                         SEQUENCE LISTING

<110>  Yale University
       Rosen, Connor
       Wang, Eric
       Ring, Aaron
       Dai, Yile
 
<120>  Rapid Extracellular Antibody Profiling (REAP) for the Discovery 
       of Antibodies in High-Throughput and Use of Said Antibodies

<130>  047162-5287-00WO

<150>  US 62/992,484
<151>  2020-03-20

<160>  6193  

<170>  PatentIn version 3.5

<210>  1
<211>  474
<212>  PRT
<213>  Homo Sapiens

<400>  1

Ala Ile Phe Tyr Glu Thr Gln Pro Ser Leu Trp Ala Glu Ser Glu Ser 
1               5                   10                  15      


Leu Leu Lys Pro Leu Ala Asn Val Thr Leu Thr Cys Gln Ala Arg Leu 
            20                  25                  30          


Glu Thr Pro Asp Phe Gln Leu Phe Lys Asn Gly Val Ala Gln Glu Pro 
        35                  40                  45              


Val His Leu Asp Ser Pro Ala Ile Lys His Gln Phe Leu Leu Thr Gly 
    50                  55                  60                  


Asp Thr Gln Gly Arg Tyr Arg Cys Arg Ser Gly Leu Ser Thr Gly Trp 
65                  70                  75                  80  


Thr Gln Leu Ser Lys Leu Leu Glu Leu Thr Gly Pro Lys Ser Leu Pro 
                85                  90                  95      


Ala Pro Trp Leu Ser Met Ala Pro Val Ser Trp Ile Thr Pro Gly Leu 
            100                 105                 110         


Lys Thr Thr Ala Val Cys Arg Gly Val Leu Arg Gly Val Thr Phe Leu 
        115                 120                 125             


Leu Arg Arg Glu Gly Asp His Glu Phe Leu Glu Val Pro Glu Ala Gln 
    130                 135                 140                 


Glu Asp Val Glu Ala Thr Phe Pro Val His Gln Pro Gly Asn Tyr Ser 
145                 150                 155                 160 


Cys Ser Tyr Arg Thr Asp Gly Glu Gly Ala Leu Ser Glu Pro Ser Ala 
                165                 170                 175     


Thr Val Thr Ile Glu Glu Leu Ala Ala Pro Pro Pro Pro Val Leu Met 
            180                 185                 190         


His His Gly Glu Ser Ser Gln Val Leu His Pro Gly Asn Lys Val Thr 
        195                 200                 205             


Leu Thr Cys Val Ala Pro Leu Ser Gly Val Asp Phe Gln Leu Arg Arg 
    210                 215                 220                 


Gly Glu Lys Glu Leu Leu Val Pro Arg Ser Ser Thr Ser Pro Asp Arg 
225                 230                 235                 240 


Ile Phe Phe His Leu Asn Ala Val Ala Leu Gly Asp Gly Gly His Tyr 
                245                 250                 255     


Thr Cys Arg Tyr Arg Leu His Asp Asn Gln Asn Gly Trp Ser Gly Asp 
            260                 265                 270         


Ser Ala Pro Val Glu Leu Ile Leu Ser Asp Glu Thr Leu Pro Ala Pro 
        275                 280                 285             


Glu Phe Ser Pro Glu Pro Glu Ser Gly Arg Ala Leu Arg Leu Arg Cys 
    290                 295                 300                 


Leu Ala Pro Leu Glu Gly Ala Arg Phe Ala Leu Val Arg Glu Asp Arg 
305                 310                 315                 320 


Gly Gly Arg Arg Val His Arg Phe Gln Ser Pro Ala Gly Thr Glu Ala 
                325                 330                 335     


Leu Phe Glu Leu His Asn Ile Ser Val Ala Asp Ser Ala Asn Tyr Ser 
            340                 345                 350         


Cys Val Tyr Val Asp Leu Lys Pro Pro Phe Gly Gly Ser Ala Pro Ser 
        355                 360                 365             


Glu Arg Leu Glu Leu His Val Asp Gly Pro Pro Pro Arg Pro Gln Leu 
    370                 375                 380                 


Arg Ala Thr Trp Ser Gly Ala Val Leu Ala Gly Arg Asp Ala Val Leu 
385                 390                 395                 400 


Arg Cys Glu Gly Pro Ile Pro Asp Val Thr Phe Glu Leu Leu Arg Glu 
                405                 410                 415     


Gly Glu Thr Lys Ala Val Lys Thr Val Arg Thr Pro Gly Ala Ala Ala 
            420                 425                 430         


Asn Leu Glu Leu Ile Phe Val Gly Pro Gln His Ala Gly Asn Tyr Arg 
        435                 440                 445             


Cys Arg Tyr Arg Ser Trp Val Pro His Thr Phe Glu Ser Glu Leu Ser 
    450                 455                 460                 


Asp Pro Val Glu Leu Leu Val Ala Glu Ser 
465                 470                 


<210>  2
<211>  1451
<212>  PRT
<213>  Homo Sapiens

<400>  2

Ser Val Ser Gly Lys Pro Gln Tyr Met Val Leu Val Pro Ser Leu Leu 
1               5                   10                  15      


His Thr Glu Thr Thr Glu Lys Gly Cys Val Leu Leu Ser Tyr Leu Asn 
            20                  25                  30          


Glu Thr Val Thr Val Ser Ala Ser Leu Glu Ser Val Arg Gly Asn Arg 
        35                  40                  45              


Ser Leu Phe Thr Asp Leu Glu Ala Glu Asn Asp Val Leu His Cys Val 
    50                  55                  60                  


Ala Phe Ala Val Pro Lys Ser Ser Ser Asn Glu Glu Val Met Phe Leu 
65                  70                  75                  80  


Thr Val Gln Val Lys Gly Pro Thr Gln Glu Phe Lys Lys Arg Thr Thr 
                85                  90                  95      


Val Met Val Lys Asn Glu Asp Ser Leu Val Phe Val Gln Thr Asp Lys 
            100                 105                 110         


Ser Ile Tyr Lys Pro Gly Gln Thr Val Lys Phe Arg Val Val Ser Met 
        115                 120                 125             


Asp Glu Asn Phe His Pro Leu Asn Glu Leu Ile Pro Leu Val Tyr Ile 
    130                 135                 140                 


Gln Asp Pro Lys Gly Asn Arg Ile Ala Gln Trp Gln Ser Phe Gln Leu 
145                 150                 155                 160 


Glu Gly Gly Leu Lys Gln Phe Ser Phe Pro Leu Ser Ser Glu Pro Phe 
                165                 170                 175     


Gln Gly Ser Tyr Lys Val Val Val Gln Lys Lys Ser Gly Gly Arg Thr 
            180                 185                 190         


Glu His Pro Phe Thr Val Glu Glu Phe Val Leu Pro Lys Phe Glu Val 
        195                 200                 205             


Gln Val Thr Val Pro Lys Ile Ile Thr Ile Leu Glu Glu Glu Met Asn 
    210                 215                 220                 


Val Ser Val Cys Gly Leu Tyr Thr Tyr Gly Lys Pro Val Pro Gly His 
225                 230                 235                 240 


Val Thr Val Ser Ile Cys Arg Lys Tyr Ser Asp Ala Ser Asp Cys His 
                245                 250                 255     


Gly Glu Asp Ser Gln Ala Phe Cys Glu Lys Phe Ser Gly Gln Leu Asn 
            260                 265                 270         


Ser His Gly Cys Phe Tyr Gln Gln Val Lys Thr Lys Val Phe Gln Leu 
        275                 280                 285             


Lys Arg Lys Glu Tyr Glu Met Lys Leu His Thr Glu Ala Gln Ile Gln 
    290                 295                 300                 


Glu Glu Gly Thr Val Val Glu Leu Thr Gly Arg Gln Ser Ser Glu Ile 
305                 310                 315                 320 


Thr Arg Thr Ile Thr Lys Leu Ser Phe Val Lys Val Asp Ser His Phe 
                325                 330                 335     


Arg Gln Gly Ile Pro Phe Phe Gly Gln Val Arg Leu Val Asp Gly Lys 
            340                 345                 350         


Gly Val Pro Ile Pro Asn Lys Val Ile Phe Ile Arg Gly Asn Glu Ala 
        355                 360                 365             


Asn Tyr Tyr Ser Asn Ala Thr Thr Asp Glu His Gly Leu Val Gln Phe 
    370                 375                 380                 


Ser Ile Asn Thr Thr Asn Val Met Gly Thr Ser Leu Thr Val Arg Val 
385                 390                 395                 400 


Asn Tyr Lys Asp Arg Ser Pro Cys Tyr Gly Tyr Gln Trp Val Ser Glu 
                405                 410                 415     


Glu His Glu Glu Ala His His Thr Ala Tyr Leu Val Phe Ser Pro Ser 
            420                 425                 430         


Lys Ser Phe Val His Leu Glu Pro Met Ser His Glu Leu Pro Cys Gly 
        435                 440                 445             


His Thr Gln Thr Val Gln Ala His Tyr Ile Leu Asn Gly Gly Thr Leu 
    450                 455                 460                 


Leu Gly Leu Lys Lys Leu Ser Phe Tyr Tyr Leu Ile Met Ala Lys Gly 
465                 470                 475                 480 


Gly Ile Val Arg Thr Gly Thr His Gly Leu Leu Val Lys Gln Glu Asp 
                485                 490                 495     


Met Lys Gly His Phe Ser Ile Ser Ile Pro Val Lys Ser Asp Ile Ala 
            500                 505                 510         


Pro Val Ala Arg Leu Leu Ile Tyr Ala Val Leu Pro Thr Gly Asp Val 
        515                 520                 525             


Ile Gly Asp Ser Ala Lys Tyr Asp Val Glu Asn Cys Leu Ala Asn Lys 
    530                 535                 540                 


Val Asp Leu Ser Phe Ser Pro Ser Gln Ser Leu Pro Ala Ser His Ala 
545                 550                 555                 560 


His Leu Arg Val Thr Ala Ala Pro Gln Ser Val Cys Ala Leu Arg Ala 
                565                 570                 575     


Val Asp Gln Ser Val Leu Leu Met Lys Pro Asp Ala Glu Leu Ser Ala 
            580                 585                 590         


Ser Ser Val Tyr Asn Leu Leu Pro Glu Lys Asp Leu Thr Gly Phe Pro 
        595                 600                 605             


Gly Pro Leu Asn Asp Gln Asp Asp Glu Asp Cys Ile Asn Arg His Asn 
    610                 615                 620                 


Val Tyr Ile Asn Gly Ile Thr Tyr Thr Pro Val Ser Ser Thr Asn Glu 
625                 630                 635                 640 


Lys Asp Met Tyr Ser Phe Leu Glu Asp Met Gly Leu Lys Ala Phe Thr 
                645                 650                 655     


Asn Ser Lys Ile Arg Lys Pro Lys Met Cys Pro Gln Leu Gln Gln Tyr 
            660                 665                 670         


Glu Met His Gly Pro Glu Gly Leu Arg Val Gly Phe Tyr Glu Ser Asp 
        675                 680                 685             


Val Met Gly Arg Gly His Ala Arg Leu Val His Val Glu Glu Pro His 
    690                 695                 700                 


Thr Glu Thr Val Arg Lys Tyr Phe Pro Glu Thr Trp Ile Trp Asp Leu 
705                 710                 715                 720 


Val Val Val Asn Ser Ala Gly Val Ala Glu Val Gly Val Thr Val Pro 
                725                 730                 735     


Asp Thr Ile Thr Glu Trp Lys Ala Gly Ala Phe Cys Leu Ser Glu Asp 
            740                 745                 750         


Ala Gly Leu Gly Ile Ser Ser Thr Ala Ser Leu Arg Ala Phe Gln Pro 
        755                 760                 765             


Phe Phe Val Glu Leu Thr Met Pro Tyr Ser Val Ile Arg Gly Glu Ala 
    770                 775                 780                 


Phe Thr Leu Lys Ala Thr Val Leu Asn Tyr Leu Pro Lys Cys Ile Arg 
785                 790                 795                 800 


Val Ser Val Gln Leu Glu Ala Ser Pro Ala Phe Leu Ala Val Pro Val 
                805                 810                 815     


Glu Lys Glu Gln Ala Pro His Cys Ile Cys Ala Asn Gly Arg Gln Thr 
            820                 825                 830         


Val Ser Trp Ala Val Thr Pro Lys Ser Leu Gly Asn Val Asn Phe Thr 
        835                 840                 845             


Val Ser Ala Glu Ala Leu Glu Ser Gln Glu Leu Cys Gly Thr Glu Val 
    850                 855                 860                 


Pro Ser Val Pro Glu His Gly Arg Lys Asp Thr Val Ile Lys Pro Leu 
865                 870                 875                 880 


Leu Val Glu Pro Glu Gly Leu Glu Lys Glu Thr Thr Phe Asn Ser Leu 
                885                 890                 895     


Leu Cys Pro Ser Gly Gly Glu Val Ser Glu Glu Leu Ser Leu Lys Leu 
            900                 905                 910         


Pro Pro Asn Val Val Glu Glu Ser Ala Arg Ala Ser Val Ser Val Leu 
        915                 920                 925             


Gly Asp Ile Leu Gly Ser Ala Met Gln Asn Thr Gln Asn Leu Leu Gln 
    930                 935                 940                 


Met Pro Tyr Gly Cys Gly Glu Gln Asn Met Val Leu Phe Ala Pro Asn 
945                 950                 955                 960 


Ile Tyr Val Leu Asp Tyr Leu Asn Glu Thr Gln Gln Leu Thr Pro Glu 
                965                 970                 975     


Val Lys Ser Lys Ala Ile Gly Tyr Leu Asn Thr Gly Tyr Gln Arg Gln 
            980                 985                 990         


Leu Asn Tyr Lys His Tyr Asp Gly  Ser Tyr Ser Thr Phe  Gly Glu Arg 
        995                 1000                 1005             


Tyr Gly  Arg Asn Gln Gly Asn  Thr Trp Leu Thr Ala  Phe Val Leu 
    1010                 1015                 1020             


Lys Thr  Phe Ala Gln Ala Arg  Ala Tyr Ile Phe Ile  Asp Glu Ala 
    1025                 1030                 1035             


His Ile  Thr Gln Ala Leu Ile  Trp Leu Ser Gln Arg  Gln Lys Asp 
    1040                 1045                 1050             


Asn Gly  Cys Phe Arg Ser Ser  Gly Ser Leu Leu Asn  Asn Ala Ile 
    1055                 1060                 1065             


Lys Gly  Gly Val Glu Asp Glu  Val Thr Leu Ser Ala  Tyr Ile Thr 
    1070                 1075                 1080             


Ile Ala  Leu Leu Glu Ile Pro  Leu Thr Val Thr His  Pro Val Val 
    1085                 1090                 1095             


Arg Asn  Ala Leu Phe Cys Leu  Glu Ser Ala Trp Lys  Thr Ala Gln 
    1100                 1105                 1110             


Glu Gly  Asp His Gly Ser His  Val Tyr Thr Lys Ala  Leu Leu Ala 
    1115                 1120                 1125             


Tyr Ala  Phe Ala Leu Ala Gly  Asn Gln Asp Lys Arg  Lys Glu Val 
    1130                 1135                 1140             


Leu Lys  Ser Leu Asn Glu Glu  Ala Val Lys Lys Asp  Asn Ser Val 
    1145                 1150                 1155             


His Trp  Glu Arg Pro Gln Lys  Pro Lys Ala Pro Val  Gly His Phe 
    1160                 1165                 1170             


Tyr Glu  Pro Gln Ala Pro Ser  Ala Glu Val Glu Met  Thr Ser Tyr 
    1175                 1180                 1185             


Val Leu  Leu Ala Tyr Leu Thr  Ala Gln Pro Ala Pro  Thr Ser Glu 
    1190                 1195                 1200             


Asp Leu  Thr Ser Ala Thr Asn  Ile Val Lys Trp Ile  Thr Lys Gln 
    1205                 1210                 1215             


Gln Asn  Ala Gln Gly Gly Phe  Ser Ser Thr Gln Asp  Thr Val Val 
    1220                 1225                 1230             


Ala Leu  His Ala Leu Ser Lys  Tyr Gly Ala Ala Thr  Phe Thr Arg 
    1235                 1240                 1245             


Thr Gly  Lys Ala Ala Gln Val  Thr Ile Gln Ser Ser  Gly Thr Phe 
    1250                 1255                 1260             


Ser Ser  Lys Phe Gln Val Asp  Asn Asn Asn Arg Leu  Leu Leu Gln 
    1265                 1270                 1275             


Gln Val  Ser Leu Pro Glu Leu  Pro Gly Glu Tyr Ser  Met Lys Val 
    1280                 1285                 1290             


Thr Gly  Glu Gly Cys Val Tyr  Leu Gln Thr Ser Leu  Lys Tyr Asn 
    1295                 1300                 1305             


Ile Leu  Pro Glu Lys Glu Glu  Phe Pro Phe Ala Leu  Gly Val Gln 
    1310                 1315                 1320             


Thr Leu  Pro Gln Thr Cys Asp  Glu Pro Lys Ala His  Thr Ser Phe 
    1325                 1330                 1335             


Gln Ile  Ser Leu Ser Val Ser  Tyr Thr Gly Ser Arg  Ser Ala Ser 
    1340                 1345                 1350             


Asn Met  Ala Ile Val Asp Val  Lys Met Val Ser Gly  Phe Ile Pro 
    1355                 1360                 1365             


Leu Lys  Pro Thr Val Lys Met  Leu Glu Arg Ser Asn  His Val Ser 
    1370                 1375                 1380             


Arg Thr  Glu Val Ser Ser Asn  His Val Leu Ile Tyr  Leu Asp Lys 
    1385                 1390                 1395             


Val Ser  Asn Gln Thr Leu Ser  Leu Phe Phe Thr Val  Leu Gln Asp 
    1400                 1405                 1410             


Val Pro  Val Arg Asp Leu Lys  Pro Ala Ile Val Lys  Val Tyr Asp 
    1415                 1420                 1425             


Tyr Tyr  Glu Thr Asp Glu Phe  Ala Ile Ala Glu Tyr  Asn Ala Pro 
    1430                 1435                 1440             


Cys Ser  Lys Asp Leu Gly Asn  Ala 
    1445                 1450     


<210>  3
<211>  1047
<212>  PRT
<213>  Homo Sapiens

<400>  3

Gln Lys Leu Pro Lys Gly Lys Arg Pro Asn Leu Lys Val His Ile Asn 
1               5                   10                  15      


Thr Thr Ser Asp Ser Ile Leu Leu Lys Phe Leu Arg Pro Ser Pro Asn 
            20                  25                  30          


Val Lys Leu Glu Gly Leu Leu Leu Gly Tyr Gly Ser Asn Val Ser Pro 
        35                  40                  45              


Asn Gln Tyr Phe Pro Leu Pro Ala Glu Gly Lys Phe Thr Glu Ala Ile 
    50                  55                  60                  


Val Asp Ala Glu Pro Lys Tyr Leu Ile Val Val Arg Pro Ala Pro Pro 
65                  70                  75                  80  


Pro Ser Gln Lys Lys Ser Cys Ser Gly Lys Thr Arg Ser Arg Lys Pro 
                85                  90                  95      


Leu Gln Leu Val Val Gly Thr Leu Thr Pro Ser Ser Val Phe Leu Ser 
            100                 105                 110         


Trp Gly Phe Leu Ile Asn Pro His His Asp Trp Thr Leu Pro Ser His 
        115                 120                 125             


Cys Pro Asn Asp Arg Phe Tyr Thr Ile Arg Tyr Arg Glu Lys Asp Lys 
    130                 135                 140                 


Glu Lys Lys Trp Ile Phe Gln Ile Cys Pro Ala Thr Glu Thr Ile Val 
145                 150                 155                 160 


Glu Asn Leu Lys Pro Asn Thr Val Tyr Glu Phe Gly Val Lys Asp Asn 
                165                 170                 175     


Val Glu Gly Gly Ile Trp Ser Lys Ile Phe Asn His Lys Thr Val Val 
            180                 185                 190         


Gly Ser Lys Lys Val Asn Gly Lys Ile Gln Ser Thr Tyr Asp Gln Asp 
        195                 200                 205             


His Thr Val Pro Ala Tyr Val Pro Arg Lys Leu Ile Pro Ile Thr Ile 
    210                 215                 220                 


Ile Lys Gln Val Ile Gln Asn Val Thr His Lys Asp Ser Ala Lys Ser 
225                 230                 235                 240 


Pro Glu Lys Ala Pro Leu Gly Gly Val Ile Leu Val His Leu Ile Ile 
                245                 250                 255     


Pro Gly Leu Asn Glu Thr Thr Val Lys Leu Pro Ala Ser Leu Met Phe 
            260                 265                 270         


Glu Ile Ser Asp Ala Leu Lys Thr Gln Leu Ala Lys Asn Glu Thr Leu 
        275                 280                 285             


Ala Leu Pro Ala Glu Ser Lys Thr Pro Glu Val Glu Lys Ile Ser Ala 
    290                 295                 300                 


Arg Pro Thr Thr Val Thr Pro Glu Thr Val Pro Arg Ser Thr Lys Pro 
305                 310                 315                 320 


Thr Thr Ser Ser Ala Leu Asp Val Ser Glu Thr Thr Leu Ala Ser Ser 
                325                 330                 335     


Glu Lys Pro Trp Ile Val Pro Thr Ala Lys Ile Ser Glu Asp Ser Lys 
            340                 345                 350         


Val Leu Gln Pro Gln Thr Ala Thr Tyr Asp Val Phe Ser Ser Pro Thr 
        355                 360                 365             


Thr Ser Asp Glu Pro Glu Ile Ser Asp Ser Tyr Thr Ala Thr Ser Asp 
    370                 375                 380                 


Arg Ile Leu Asp Ser Ile Pro Pro Lys Thr Ser Arg Thr Leu Glu Gln 
385                 390                 395                 400 


Pro Arg Ala Thr Leu Ala Pro Ser Glu Thr Pro Phe Val Pro Gln Lys 
                405                 410                 415     


Leu Glu Ile Phe Thr Ser Pro Glu Met Gln Pro Thr Thr Pro Ala Pro 
            420                 425                 430         


Gln Gln Thr Thr Ser Ile Pro Ser Thr Pro Lys Arg Arg Pro Arg Pro 
        435                 440                 445             


Lys Pro Pro Arg Thr Lys Pro Glu Arg Thr Thr Ser Ala Gly Thr Ile 
    450                 455                 460                 


Thr Pro Lys Ile Ser Lys Ser Pro Glu Pro Thr Trp Thr Thr Pro Ala 
465                 470                 475                 480 


Pro Gly Lys Thr Gln Phe Ile Ser Leu Lys Pro Lys Ile Pro Leu Ser 
                485                 490                 495     


Pro Glu Val Thr His Thr Lys Pro Ala Pro Lys Gln Thr Pro Arg Ala 
            500                 505                 510         


Pro Pro Lys Pro Lys Thr Ser Pro Arg Pro Arg Ile Pro Gln Thr Gln 
        515                 520                 525             


Pro Val Pro Lys Val Pro Gln Arg Val Thr Ala Lys Pro Lys Thr Ser 
    530                 535                 540                 


Pro Ser Pro Glu Val Ser Tyr Thr Thr Pro Ala Pro Lys Asp Val Leu 
545                 550                 555                 560 


Leu Pro His Lys Pro Tyr Pro Glu Val Ser Gln Ser Glu Pro Ala Pro 
                565                 570                 575     


Leu Glu Thr Arg Gly Ile Pro Phe Ile Pro Met Ile Ser Pro Ser Pro 
            580                 585                 590         


Ser Gln Glu Glu Leu Gln Thr Thr Leu Glu Glu Thr Asp Gln Ser Thr 
        595                 600                 605             


Gln Glu Pro Phe Thr Thr Lys Ile Pro Arg Thr Thr Glu Leu Ala Lys 
    610                 615                 620                 


Thr Thr Gln Ala Pro His Arg Phe Tyr Thr Thr Val Arg Pro Arg Thr 
625                 630                 635                 640 


Ser Asp Lys Pro His Ile Arg Pro Gly Val Lys Gln Ala Pro Arg Pro 
                645                 650                 655     


Ser Gly Ala Asp Arg Asn Val Ser Val Asp Ser Thr His Pro Thr Lys 
            660                 665                 670         


Lys Pro Gly Thr Arg Arg Pro Pro Leu Pro Pro Arg Pro Thr His Pro 
        675                 680                 685             


Arg Arg Lys Pro Leu Pro Pro Asn Asn Val Thr Gly Lys Pro Gly Ser 
    690                 695                 700                 


Ala Gly Ile Ile Ser Ser Gly Pro Ile Thr Thr Pro Pro Leu Arg Ser 
705                 710                 715                 720 


Thr Pro Arg Pro Thr Gly Thr Pro Leu Glu Arg Ile Glu Thr Asp Ile 
                725                 730                 735     


Lys Gln Pro Thr Val Pro Ala Ser Gly Glu Glu Leu Glu Asn Ile Thr 
            740                 745                 750         


Asp Phe Ser Ser Ser Pro Thr Arg Glu Thr Asp Pro Leu Gly Lys Pro 
        755                 760                 765             


Arg Phe Lys Gly Pro His Val Arg Tyr Ile Gln Lys Pro Asp Asn Ser 
    770                 775                 780                 


Pro Cys Ser Ile Thr Asp Ser Val Lys Arg Phe Pro Lys Glu Glu Ala 
785                 790                 795                 800 


Thr Glu Gly Asn Ala Thr Ser Pro Pro Gln Asn Pro Pro Thr Asn Leu 
                805                 810                 815     


Thr Val Val Thr Val Glu Gly Cys Pro Ser Phe Val Ile Leu Asp Trp 
            820                 825                 830         


Glu Lys Pro Leu Asn Asp Thr Val Thr Glu Tyr Glu Val Ile Ser Arg 
        835                 840                 845             


Glu Asn Gly Ser Phe Ser Gly Lys Asn Lys Ser Ile Gln Met Thr Asn 
    850                 855                 860                 


Gln Thr Phe Ser Thr Val Glu Asn Leu Lys Pro Asn Thr Ser Tyr Glu 
865                 870                 875                 880 


Phe Gln Val Lys Pro Lys Asn Pro Leu Gly Glu Gly Pro Val Ser Asn 
                885                 890                 895     


Thr Val Ala Phe Ser Thr Glu Ser Ala Asp Pro Arg Val Ser Glu Pro 
            900                 905                 910         


Val Ser Ala Gly Arg Asp Ala Ile Trp Thr Glu Arg Pro Phe Asn Ser 
        915                 920                 925             


Asp Ser Tyr Ser Glu Cys Lys Gly Lys Gln Tyr Val Lys Arg Thr Trp 
    930                 935                 940                 


Tyr Lys Lys Phe Val Gly Val Gln Leu Cys Asn Ser Leu Arg Tyr Lys 
945                 950                 955                 960 


Ile Tyr Leu Ser Asp Ser Leu Thr Gly Lys Phe Tyr Asn Ile Gly Asp 
                965                 970                 975     


Gln Arg Gly His Gly Glu Asp His Cys Gln Phe Val Asp Ser Phe Leu 
            980                 985                 990         


Asp Gly Arg Thr Gly Gln Gln Leu  Thr Ser Asp Gln Leu  Pro Ile Lys 
        995                 1000                 1005             


Glu Gly  Tyr Phe Arg Ala Val  Arg Gln Glu Pro Val  Gln Phe Gly 
    1010                 1015                 1020             


Glu Ile  Gly Gly His Thr Gln  Ile Asn Tyr Val Gln  Trp Tyr Glu 
    1025                 1030                 1035             


Cys Gly  Thr Thr Ile Pro Gly  Lys Trp 
    1040                 1045         


<210>  4
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  4

Pro Gln Pro Ser Pro Leu Arg Val Leu Leu Gly Thr Ser Leu Thr Ile 
1               5                   10                  15      


Pro Cys Tyr Phe Ile Asp Pro Met His Pro Val Thr Thr Ala Pro Ser 
            20                  25                  30          


Thr Ala Pro Leu Ala Pro Arg Ile Lys Trp Ser Arg Val Ser Lys Glu 
        35                  40                  45              


Lys Glu Val Val Leu Leu Val Ala Thr Glu Gly Arg Val Arg Val Asn 
    50                  55                  60                  


Ser Ala Tyr Gln Asp Lys Val Ser Leu Pro Asn Tyr Pro Ala Ile Pro 
65                  70                  75                  80  


Ser Asp Ala Thr Leu Glu Val Gln Ser Leu Arg Ser Asn Asp Ser Gly 
                85                  90                  95      


Val Tyr Arg Cys Glu Val Met His Gly Ile Glu Asp Ser Glu Ala Thr 
            100                 105                 110         


Leu Glu 
        


<210>  5
<211>  723
<212>  PRT
<213>  Homo Sapiens

<400>  5

Gln Ser Thr Ile Glu Glu Gln Ala Lys Thr Phe Leu Asp Lys Phe Asn 
1               5                   10                  15      


His Glu Ala Glu Asp Leu Phe Tyr Gln Ser Ser Leu Ala Ser Trp Asn 
            20                  25                  30          


Tyr Asn Thr Asn Ile Thr Glu Glu Asn Val Gln Asn Met Asn Asn Ala 
        35                  40                  45              


Gly Asp Lys Trp Ser Ala Phe Leu Lys Glu Gln Ser Thr Leu Ala Gln 
    50                  55                  60                  


Met Tyr Pro Leu Gln Glu Ile Gln Asn Leu Thr Val Lys Leu Gln Leu 
65                  70                  75                  80  


Gln Ala Leu Gln Gln Asn Gly Ser Ser Val Leu Ser Glu Asp Lys Ser 
                85                  90                  95      


Lys Arg Leu Asn Thr Ile Leu Asn Thr Met Ser Thr Ile Tyr Ser Thr 
            100                 105                 110         


Gly Lys Val Cys Asn Pro Asp Asn Pro Gln Glu Cys Leu Leu Leu Glu 
        115                 120                 125             


Pro Gly Leu Asn Glu Ile Met Ala Asn Ser Leu Asp Tyr Asn Glu Arg 
    130                 135                 140                 


Leu Trp Ala Trp Glu Ser Trp Arg Ser Glu Val Gly Lys Gln Leu Arg 
145                 150                 155                 160 


Pro Leu Tyr Glu Glu Tyr Val Val Leu Lys Asn Glu Met Ala Arg Ala 
                165                 170                 175     


Asn His Tyr Glu Asp Tyr Gly Asp Tyr Trp Arg Gly Asp Tyr Glu Val 
            180                 185                 190         


Asn Gly Val Asp Gly Tyr Asp Tyr Ser Arg Gly Gln Leu Ile Glu Asp 
        195                 200                 205             


Val Glu His Thr Phe Glu Glu Ile Lys Pro Leu Tyr Glu His Leu His 
    210                 215                 220                 


Ala Tyr Val Arg Ala Lys Leu Met Asn Ala Tyr Pro Ser Tyr Ile Ser 
225                 230                 235                 240 


Pro Ile Gly Cys Leu Pro Ala His Leu Leu Gly Asp Met Trp Gly Arg 
                245                 250                 255     


Phe Trp Thr Asn Leu Tyr Ser Leu Thr Val Pro Phe Gly Gln Lys Pro 
            260                 265                 270         


Asn Ile Asp Val Thr Asp Ala Met Val Asp Gln Ala Trp Asp Ala Gln 
        275                 280                 285             


Arg Ile Phe Lys Glu Ala Glu Lys Phe Phe Val Ser Val Gly Leu Pro 
    290                 295                 300                 


Asn Met Thr Gln Gly Phe Trp Glu Asn Ser Met Leu Thr Asp Pro Gly 
305                 310                 315                 320 


Asn Val Gln Lys Ala Val Cys His Pro Thr Ala Trp Asp Leu Gly Lys 
                325                 330                 335     


Gly Asp Phe Arg Ile Leu Met Cys Thr Lys Val Thr Met Asp Asp Phe 
            340                 345                 350         


Leu Thr Ala His His Glu Met Gly His Ile Gln Tyr Asp Met Ala Tyr 
        355                 360                 365             


Ala Ala Gln Pro Phe Leu Leu Arg Asn Gly Ala Asn Glu Gly Phe His 
    370                 375                 380                 


Glu Ala Val Gly Glu Ile Met Ser Leu Ser Ala Ala Thr Pro Lys His 
385                 390                 395                 400 


Leu Lys Ser Ile Gly Leu Leu Ser Pro Asp Phe Gln Glu Asp Asn Glu 
                405                 410                 415     


Thr Glu Ile Asn Phe Leu Leu Lys Gln Ala Leu Thr Ile Val Gly Thr 
            420                 425                 430         


Leu Pro Phe Thr Tyr Met Leu Glu Lys Trp Arg Trp Met Val Phe Lys 
        435                 440                 445             


Gly Glu Ile Pro Lys Asp Gln Trp Met Lys Lys Trp Trp Glu Met Lys 
    450                 455                 460                 


Arg Glu Ile Val Gly Val Val Glu Pro Val Pro His Asp Glu Thr Tyr 
465                 470                 475                 480 


Cys Asp Pro Ala Ser Leu Phe His Val Ser Asn Asp Tyr Ser Phe Ile 
                485                 490                 495     


Arg Tyr Tyr Thr Arg Thr Leu Tyr Gln Phe Gln Phe Gln Glu Ala Leu 
            500                 505                 510         


Cys Gln Ala Ala Lys His Glu Gly Pro Leu His Lys Cys Asp Ile Ser 
        515                 520                 525             


Asn Ser Thr Glu Ala Gly Gln Lys Leu Phe Asn Met Leu Arg Leu Gly 
    530                 535                 540                 


Lys Ser Glu Pro Trp Thr Leu Ala Leu Glu Asn Val Val Gly Ala Lys 
545                 550                 555                 560 


Asn Met Asn Val Arg Pro Leu Leu Asn Tyr Phe Glu Pro Leu Phe Thr 
                565                 570                 575     


Trp Leu Lys Asp Gln Asn Lys Asn Ser Phe Val Gly Trp Ser Thr Asp 
            580                 585                 590         


Trp Ser Pro Tyr Ala Asp Gln Ser Ile Lys Val Arg Ile Ser Leu Lys 
        595                 600                 605             


Ser Ala Leu Gly Asp Lys Ala Tyr Glu Trp Asn Asp Asn Glu Met Tyr 
    610                 615                 620                 


Leu Phe Arg Ser Ser Val Ala Tyr Ala Met Arg Gln Tyr Phe Leu Lys 
625                 630                 635                 640 


Val Lys Asn Gln Met Ile Leu Phe Gly Glu Glu Asp Val Arg Val Ala 
                645                 650                 655     


Asn Leu Lys Pro Arg Ile Ser Phe Asn Phe Phe Val Thr Ala Pro Lys 
            660                 665                 670         


Asn Val Ser Asp Ile Ile Pro Arg Thr Glu Val Glu Lys Ala Ile Arg 
        675                 680                 685             


Met Ser Arg Ser Arg Ile Asn Asp Ala Phe Arg Leu Asn Asp Asn Ser 
    690                 695                 700                 


Leu Glu Phe Leu Gly Ile Gln Pro Thr Leu Gly Pro Pro Asn Gln Pro 
705                 710                 715                 720 


Pro Val Ser 
            


<210>  6
<211>  509
<212>  PRT
<213>  Homo Sapiens

<400>  6

Gln Val Arg Arg Gly His Pro Thr Val His Ser Glu Thr Lys Tyr Val 
1               5                   10                  15      


Glu Leu Ile Val Ile Asn Asp His Gln Leu Phe Glu Gln Met Arg Gln 
            20                  25                  30          


Ser Val Val Leu Thr Ser Asn Phe Ala Lys Ser Val Val Asn Leu Ala 
        35                  40                  45              


Asp Val Ile Tyr Lys Glu Gln Leu Asn Thr Arg Ile Val Leu Val Ala 
    50                  55                  60                  


Met Glu Thr Trp Ala Asp Gly Asp Lys Ile Gln Val Gln Asp Asp Leu 
65                  70                  75                  80  


Leu Glu Thr Leu Ala Arg Leu Met Val Tyr Arg Arg Glu Gly Leu Pro 
                85                  90                  95      


Glu Pro Ser Asp Ala Thr His Leu Phe Ser Gly Arg Thr Phe Gln Ser 
            100                 105                 110         


Thr Ser Ser Gly Ala Ala Tyr Val Gly Gly Ile Cys Ser Leu Ser His 
        115                 120                 125             


Gly Gly Gly Val Asn Glu Tyr Gly Asn Met Gly Ala Met Ala Val Thr 
    130                 135                 140                 


Leu Ala Gln Thr Leu Gly Gln Asn Leu Gly Met Met Trp Asn Lys His 
145                 150                 155                 160 


Arg Ser Ser Ala Gly Asp Cys Lys Cys Pro Asp Ile Trp Leu Gly Cys 
                165                 170                 175     


Ile Met Glu Asp Thr Gly Phe Tyr Leu Pro Arg Lys Phe Ser Arg Cys 
            180                 185                 190         


Ser Ile Asp Glu Tyr Asn Gln Phe Leu Gln Glu Gly Gly Gly Ser Cys 
        195                 200                 205             


Leu Phe Asn Lys Pro Leu Lys Leu Leu Asp Pro Pro Glu Cys Gly Asn 
    210                 215                 220                 


Gly Phe Val Glu Ala Gly Glu Glu Cys Asp Cys Gly Ser Val Gln Glu 
225                 230                 235                 240 


Cys Ser Arg Ala Gly Gly Asn Cys Cys Lys Lys Cys Thr Leu Thr His 
                245                 250                 255     


Asp Ala Met Cys Ser Asp Gly Leu Cys Cys Arg Arg Cys Lys Tyr Glu 
            260                 265                 270         


Pro Arg Gly Val Ser Cys Arg Glu Ala Val Asn Glu Cys Asp Ile Ala 
        275                 280                 285             


Glu Thr Cys Thr Gly Asp Ser Ser Gln Cys Pro Pro Asn Leu His Lys 
    290                 295                 300                 


Leu Asp Gly Tyr Tyr Cys Asp His Glu Gln Gly Arg Cys Tyr Gly Gly 
305                 310                 315                 320 


Arg Cys Lys Thr Arg Asp Arg Gln Cys Gln Val Leu Trp Gly His Ala 
                325                 330                 335     


Ala Ala Asp Arg Phe Cys Tyr Glu Lys Leu Asn Val Glu Gly Thr Glu 
            340                 345                 350         


Arg Gly Ser Cys Gly Arg Lys Gly Ser Gly Trp Val Gln Cys Ser Lys 
        355                 360                 365             


Gln Asp Val Leu Cys Gly Phe Leu Leu Cys Val Asn Ile Ser Gly Ala 
    370                 375                 380                 


Pro Arg Leu Gly Asp Leu Val Gly Asp Ile Ser Ser Val Thr Phe Tyr 
385                 390                 395                 400 


His Gln Gly Lys Glu Leu Asp Cys Arg Gly Gly His Val Gln Leu Ala 
                405                 410                 415     


Asp Gly Ser Asp Leu Ser Tyr Val Glu Asp Gly Thr Ala Cys Gly Pro 
            420                 425                 430         


Asn Met Leu Cys Leu Asp His Arg Cys Leu Pro Ala Ser Ala Phe Asn 
        435                 440                 445             


Phe Ser Thr Cys Pro Gly Ser Gly Glu Arg Arg Ile Cys Ser His His 
    450                 455                 460                 


Gly Val Cys Ser Asn Glu Gly Lys Cys Ile Cys Gln Pro Asp Trp Thr 
465                 470                 475                 480 


Gly Lys Asp Cys Ser Ile His Asn Pro Leu Pro Thr Ser Pro Pro Thr 
                485                 490                 495     


Gly Glu Thr Glu Arg Tyr Lys Gly Pro Ser Gly Thr Asn 
            500                 505                 


<210>  7
<211>  533
<212>  PRT
<213>  Homo Sapiens

<400>  7

Glu Thr Leu Lys Ala Thr Lys Tyr Val Glu Leu Val Ile Val Ala Asp 
1               5                   10                  15      


Asn Arg Glu Phe Gln Arg Gln Gly Lys Asp Leu Glu Lys Val Lys Gln 
            20                  25                  30          


Arg Leu Ile Glu Ile Ala Asn His Val Asp Lys Phe Tyr Arg Pro Leu 
        35                  40                  45              


Asn Ile Arg Ile Val Leu Val Gly Val Glu Val Trp Asn Asp Met Asp 
    50                  55                  60                  


Lys Cys Ser Val Ser Gln Asp Pro Phe Thr Ser Leu His Glu Phe Leu 
65                  70                  75                  80  


Asp Trp Arg Lys Met Lys Leu Leu Pro Arg Lys Ser His Asp Asn Ala 
                85                  90                  95      


Gln Leu Val Ser Gly Val Tyr Phe Gln Gly Thr Thr Ile Gly Met Ala 
            100                 105                 110         


Pro Ile Met Ser Met Cys Thr Ala Asp Gln Ser Gly Gly Ile Val Met 
        115                 120                 125             


Asp His Ser Asp Asn Pro Leu Gly Ala Ala Val Thr Leu Ala His Glu 
    130                 135                 140                 


Leu Gly His Asn Phe Gly Met Asn His Asp Thr Leu Asp Arg Gly Cys 
145                 150                 155                 160 


Ser Cys Gln Met Ala Val Glu Lys Gly Gly Cys Ile Met Asn Ala Ser 
                165                 170                 175     


Thr Gly Tyr Pro Phe Pro Met Val Phe Ser Ser Cys Ser Arg Lys Asp 
            180                 185                 190         


Leu Glu Thr Ser Leu Glu Lys Gly Met Gly Val Cys Leu Phe Asn Leu 
        195                 200                 205             


Pro Glu Val Arg Glu Ser Phe Gly Gly Gln Lys Cys Gly Asn Arg Phe 
    210                 215                 220                 


Val Glu Glu Gly Glu Glu Cys Asp Cys Gly Glu Pro Glu Glu Cys Met 
225                 230                 235                 240 


Asn Arg Cys Cys Asn Ala Thr Thr Cys Thr Leu Lys Pro Asp Ala Val 
                245                 250                 255     


Cys Ala His Gly Leu Cys Cys Glu Asp Cys Gln Leu Lys Pro Ala Gly 
            260                 265                 270         


Thr Ala Cys Arg Asp Ser Ser Asn Ser Cys Asp Leu Pro Glu Phe Cys 
        275                 280                 285             


Thr Gly Ala Ser Pro His Cys Pro Ala Asn Val Tyr Leu His Asp Gly 
    290                 295                 300                 


His Ser Cys Gln Asp Val Asp Gly Tyr Cys Tyr Asn Gly Ile Cys Gln 
305                 310                 315                 320 


Thr His Glu Gln Gln Cys Val Thr Leu Trp Gly Pro Gly Ala Lys Pro 
                325                 330                 335     


Ala Pro Gly Ile Cys Phe Glu Arg Val Asn Ser Ala Gly Asp Pro Tyr 
            340                 345                 350         


Gly Asn Cys Gly Lys Val Ser Lys Ser Ser Phe Ala Lys Cys Glu Met 
        355                 360                 365             


Arg Asp Ala Lys Cys Gly Lys Ile Gln Cys Gln Gly Gly Ala Ser Arg 
    370                 375                 380                 


Pro Val Ile Gly Thr Asn Ala Val Ser Ile Glu Thr Asn Ile Pro Leu 
385                 390                 395                 400 


Gln Gln Gly Gly Arg Ile Leu Cys Arg Gly Thr His Val Tyr Leu Gly 
                405                 410                 415     


Asp Asp Met Pro Asp Pro Gly Leu Val Leu Ala Gly Thr Lys Cys Ala 
            420                 425                 430         


Asp Gly Lys Ile Cys Leu Asn Arg Gln Cys Gln Asn Ile Ser Val Phe 
        435                 440                 445             


Gly Val His Glu Cys Ala Met Gln Cys His Gly Arg Gly Val Cys Asn 
    450                 455                 460                 


Asn Arg Lys Asn Cys His Cys Glu Ala His Trp Ala Pro Pro Phe Cys 
465                 470                 475                 480 


Asp Lys Phe Gly Phe Gly Gly Ser Thr Asp Ser Gly Pro Ile Arg Gln 
                485                 490                 495     


Ala Gly Lys Glu Ala Arg Gln Glu Ala Ala Glu Ser Asn Arg Glu Arg 
            500                 505                 510         


Gly Gln Gly Gln Glu Pro Val Gly Ser Gln Glu His Ala Ser Thr Ala 
        515                 520                 525             


Ser Leu Thr Leu Ile 
    530             


<210>  8
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  8

Asp Val Val Thr Glu Thr Lys Thr Val Glu Leu Val Ile Val Ala Asp 
1               5                   10                  15      


His Ser Glu Ala Gln Lys Tyr Arg Asp Phe Gln His Leu Leu Asn Arg 
            20                  25                  30          


Thr Leu Glu Val Ala Leu Leu Leu Asp Thr Phe Phe Arg Pro Leu Asn 
        35                  40                  45              


Val Arg Val Ala Leu Val Gly Leu Glu Ala Trp Thr Gln Arg Asp Leu 
    50                  55                  60                  


Val Glu Ile Ser Pro Asn Pro Ala Val Thr Leu Glu Asn Phe Leu His 
65                  70                  75                  80  


Trp Arg Arg Ala His Leu Leu Pro Arg Leu Pro His Asp Ser Ala Gln 
                85                  90                  95      


Leu Val Thr Gly Thr Ser Phe Ser Gly Pro Thr Val Gly Met Ala Ile 
            100                 105                 110         


Gln Asn Ser Ile Cys Ser Pro Asp Phe Ser Gly Gly Val Asn Met Asp 
        115                 120                 125             


His Ser Thr Ser Ile Leu Gly Val Ala Ser Ser Ile Ala His Glu Leu 
    130                 135                 140                 


Gly His Ser Leu Gly Leu Asp His Asp Leu Pro Gly Asn Ser Cys Pro 
145                 150                 155                 160 


Cys Pro Gly Pro Ala Pro Ala Lys Thr Cys Ile Met Glu Ala Ser Thr 
                165                 170                 175     


Asp Phe Leu Pro Gly Leu Asn Phe Ser Asn Cys Ser Arg Arg Ala Leu 
            180                 185                 190         


Glu Lys Ala Leu Leu Asp Gly Met Gly Ser Cys Leu Phe Glu Arg Leu 
        195                 200                 205             


Pro Ser Leu Pro Pro Met Ala Ala Phe Cys Gly Asn Met Phe Val Glu 
    210                 215                 220                 


Pro Gly Glu Gln Cys Asp Cys Gly Phe Leu Asp Asp Cys Val Asp Pro 
225                 230                 235                 240 


Cys Cys Asp Ser Leu Thr Cys Gln Leu Arg Pro Gly Ala Gln Cys Ala 
                245                 250                 255     


Ser Asp Gly Pro Cys Cys Gln Asn Cys Gln Leu Arg Pro Ser Gly Trp 
            260                 265                 270         


Gln Cys Arg Pro Thr Arg Gly Asp Cys Asp Leu Pro Glu Phe Cys Pro 
        275                 280                 285             


Gly Asp Ser Ser Gln Cys Pro Pro Asp Val Ser Leu Gly Asp Gly Glu 
    290                 295                 300                 


Pro Cys Ala Gly Gly Gln Ala Val Cys Met His Gly Arg Cys Ala Ser 
305                 310                 315                 320 


Tyr Ala Gln Gln Cys Gln Ser Leu Trp Gly Pro Gly Ala Gln Pro Ala 
                325                 330                 335     


Ala Pro Leu Cys Leu Gln Thr Ala Asn Thr Arg Gly Asn Ala Phe Gly 
            340                 345                 350         


Ser Cys Gly Arg Asn Pro Ser Gly Ser Tyr Val Ser Cys Thr Pro Arg 
        355                 360                 365             


Asp Ala Ile Cys Gly Gln Leu Gln Cys Gln Thr Gly Arg Thr Gln Pro 
    370                 375                 380                 


Leu Leu Gly Ser Ile Arg Asp Leu Leu Trp Glu Thr Ile Asp Val Asn 
385                 390                 395                 400 


Gly Thr Glu Leu Asn Cys Ser Trp Val His Leu Asp Leu Gly Ser Asp 
                405                 410                 415     


Val Ala Gln Pro Leu Leu Thr Leu Pro Gly Thr Ala Cys Gly Pro Gly 
            420                 425                 430         


Leu Val Cys Ile Asp His Arg Cys Gln Arg Val Asp Leu Leu Gly Ala 
        435                 440                 445             


Gln Glu Cys Arg Ser Lys Cys His Gly His Gly Val Cys Asp Ser Asn 
    450                 455                 460                 


Arg His Cys Tyr Cys Glu Glu Gly Trp Ala Pro Pro Asp Cys Thr Thr 
465                 470                 475                 480 


Gln Leu Lys Ala Thr Ser Ser Leu Thr Thr 
                485                 490 


<210>  9
<211>  511
<212>  PRT
<213>  Homo Sapiens

<400>  9

Asn Leu Ser Lys Leu Leu Pro Gln Tyr Leu Glu Ile Tyr Ile Ile Val 
1               5                   10                  15      


Glu Lys Ala Leu Tyr Asp Tyr Met Gly Ser Glu Met Met Ala Val Thr 
            20                  25                  30          


Gln Lys Ile Val Gln Val Ile Gly Leu Val Asn Thr Met Phe Thr Gln 
        35                  40                  45              


Phe Lys Leu Thr Val Ile Leu Ser Ser Leu Glu Leu Trp Ser Asn Glu 
    50                  55                  60                  


Asn Gln Ile Ser Thr Ser Gly Asp Ala Asp Asp Ile Leu Gln Arg Phe 
65                  70                  75                  80  


Leu Ala Trp Lys Arg Asp Tyr Leu Ile Leu Arg Pro His Asp Ile Ala 
                85                  90                  95      


Tyr Leu Leu Val Tyr Arg Lys His Pro Lys Tyr Val Gly Ala Thr Phe 
            100                 105                 110         


Pro Gly Thr Val Cys Asn Lys Ser Tyr Asp Ala Gly Ile Ala Met Tyr 
        115                 120                 125             


Pro Asp Ala Ile Gly Leu Glu Gly Phe Ser Val Ile Ile Ala Gln Leu 
    130                 135                 140                 


Leu Gly Leu Asn Val Gly Leu Thr Tyr Asp Asp Ile Thr Gln Cys Phe 
145                 150                 155                 160 


Cys Leu Arg Ala Thr Cys Ile Met Asn His Glu Ala Val Ser Ala Ser 
                165                 170                 175     


Gly Arg Lys Ile Phe Ser Asn Cys Ser Met His Asp Tyr Arg Tyr Phe 
            180                 185                 190         


Val Ser Lys Phe Glu Thr Lys Cys Leu Gln Lys Leu Ser Asn Leu Gln 
        195                 200                 205             


Pro Leu His Gln Asn Gln Pro Val Cys Gly Asn Gly Ile Leu Glu Ser 
    210                 215                 220                 


Asn Glu Glu Cys Asp Cys Gly Asn Lys Asn Glu Cys Gln Phe Lys Lys 
225                 230                 235                 240 


Cys Cys Asp Tyr Asn Thr Cys Lys Leu Lys Gly Ser Val Lys Cys Gly 
                245                 250                 255     


Ser Gly Pro Cys Cys Thr Ser Lys Cys Glu Leu Ser Ile Ala Gly Thr 
            260                 265                 270         


Pro Cys Arg Lys Ser Ile Asp Pro Glu Cys Asp Phe Thr Glu Tyr Cys 
        275                 280                 285             


Asn Gly Thr Ser Ser Asn Cys Val Pro Asp Thr Tyr Ala Leu Asn Gly 
    290                 295                 300                 


Arg Leu Cys Lys Leu Gly Thr Ala Tyr Cys Tyr Asn Gly Gln Cys Gln 
305                 310                 315                 320 


Thr Thr Asp Asn Gln Cys Ala Lys Ile Phe Gly Lys Gly Ala Gln Gly 
                325                 330                 335     


Ala Pro Phe Ala Cys Phe Lys Glu Val Asn Ser Leu His Glu Arg Ser 
            340                 345                 350         


Glu Asn Cys Gly Phe Lys Asn Ser Gln Pro Leu Pro Cys Glu Arg Lys 
        355                 360                 365             


Asp Val Leu Cys Gly Lys Leu Ala Cys Val Gln Pro His Lys Asn Ala 
    370                 375                 380                 


Asn Lys Ser Asp Ala Gln Ser Thr Val Tyr Ser Tyr Ile Gln Asp His 
385                 390                 395                 400 


Val Cys Val Ser Ile Ala Thr Gly Ser Ser Met Arg Ser Asp Gly Thr 
                405                 410                 415     


Asp Asn Ala Tyr Val Ala Asp Gly Thr Met Cys Gly Pro Glu Met Tyr 
            420                 425                 430         


Cys Val Asn Lys Thr Cys Arg Lys Val His Leu Met Gly Tyr Asn Cys 
        435                 440                 445             


Asn Ala Thr Thr Lys Cys Lys Gly Lys Gly Ile Cys Asn Asn Phe Gly 
    450                 455                 460                 


Asn Cys Gln Cys Phe Pro Gly His Arg Pro Pro Asp Cys Lys Phe Gln 
465                 470                 475                 480 


Phe Gly Ser Pro Gly Gly Ser Ile Asp Asp Gly Asn Phe Gln Lys Ser 
                485                 490                 495     


Gly Asp Phe Tyr Thr Glu Lys Gly Tyr Asn Thr His Trp Asn Asn 
            500                 505                 510     


<210>  10
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  10

Arg Glu Asp Leu Asn Ser Met Lys Tyr Val Glu Leu Tyr Leu Val Ala 
1               5                   10                  15      


Asp Tyr Leu Glu Phe Gln Lys Asn Arg Arg Asp Gln Asp Ala Thr Lys 
            20                  25                  30          


His Lys Leu Ile Glu Ile Ala Asn Tyr Val Asp Lys Phe Tyr Arg Ser 
        35                  40                  45              


Leu Asn Ile Arg Ile Ala Leu Val Gly Leu Glu Val Trp Thr His Gly 
    50                  55                  60                  


Asn Met Cys Glu Val Ser Glu Asn Pro Tyr Ser Thr Leu Trp Ser Phe 
65                  70                  75                  80  


Leu Ser Trp Arg Arg Lys Leu Leu Ala Gln Lys Tyr His Asp Asn Ala 
                85                  90                  95      


Gln Leu Ile Thr Gly Met Ser Phe His Gly Thr Thr Ile Gly Leu Ala 
            100                 105                 110         


Pro Leu Met Ala Met Cys Ser Val Tyr Gln Ser Gly Gly Val Asn Met 
        115                 120                 125             


Asp His Ser Glu Asn Ala Ile Gly Val Ala Ala Thr Met Ala His Glu 
    130                 135                 140                 


Met Gly His Asn Phe Gly Met Thr His Asp Ser Ala Asp Cys Cys Ser 
145                 150                 155                 160 


Ala Ser Ala Ala Asp Gly Gly Cys Ile Met Ala Ala Ala Thr Gly His 
                165                 170                 175     


Pro Phe Pro Lys Val Phe Asn Gly Cys Asn Arg Arg Glu Leu Asp Arg 
            180                 185                 190         


Tyr Leu Gln Ser Gly Gly Gly Met Cys Leu Ser Asn Met Pro Asp Thr 
        195                 200                 205             


Arg Met Leu Tyr Gly Gly Arg Arg Cys Gly Asn Gly Tyr Leu Glu Asp 
    210                 215                 220                 


Gly Glu Glu Cys Asp Cys Gly Glu Glu Glu Glu Cys Asn Asn Pro Cys 
225                 230                 235                 240 


Cys Asn Ala Ser Asn Cys Thr Leu Arg Pro Gly Ala Glu Cys Ala His 
                245                 250                 255     


Gly Ser Cys Cys His Gln Cys Lys Leu Leu Ala Pro Gly Thr Leu Cys 
            260                 265                 270         


Arg Glu Gln Ala Arg Gln Cys Asp Leu Pro Glu Phe Cys Thr Gly Lys 
        275                 280                 285             


Ser Pro His Cys Pro Thr Asn Phe Tyr Gln Met Asp Gly Thr Pro Cys 
    290                 295                 300                 


Glu Gly Gly Gln Ala Tyr Cys Tyr Asn Gly Met Cys Leu Thr Tyr Gln 
305                 310                 315                 320 


Glu Gln Cys Gln Gln Leu Trp Gly Pro Gly Ala Arg Pro Ala Pro Asp 
                325                 330                 335     


Leu Cys Phe Glu Lys Val Asn Val Ala Gly Asp Thr Phe Gly Asn Cys 
            340                 345                 350         


Gly Lys Asp Met Asn Gly Glu His Arg Lys Cys Asn Met Arg Asp Ala 
        355                 360                 365             


Lys Cys Gly Lys Ile Gln Cys Gln Ser Ser Glu Ala Arg Pro Leu Glu 
    370                 375                 380                 


Ser Asn Ala Val Pro Ile Asp Thr Thr Ile Ile Met Asn Gly Arg Gln 
385                 390                 395                 400 


Ile Gln Cys Arg Gly Thr His Val Tyr Arg Gly Pro Glu Glu Glu Gly 
                405                 410                 415     


Asp Met Leu Asp Pro Gly Leu Val Met Thr Gly Thr Lys Cys Gly Tyr 
            420                 425                 430         


Asn His Ile Cys Phe Glu Gly Gln Cys Arg Asn Thr Ser Phe Phe Glu 
        435                 440                 445             


Thr Glu Gly Cys Gly Lys Lys Cys Asn Gly His Gly Val Cys Asn Asn 
    450                 455                 460                 


Asn Gln Asn Cys His Cys Leu Pro Gly Trp Ala Pro Pro Phe Cys Asn 
465                 470                 475                 480 


Thr Pro Gly His Gly Gly Ser Ile Asp Ser Gly Pro Met Pro Pro Glu 
                485                 490                 495     


Ser 
    


<210>  11
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  11

Tyr Asn His Met Gly Ser Asp Thr Thr Val Val Ala Gln Lys Val Phe 
1               5                   10                  15      


Gln Leu Ile Gly Leu Thr Asn Ala Ile Phe Val Ser Phe Asn Ile Thr 
            20                  25                  30          


Ile Ile Leu Ser Ser Leu Glu Leu Trp Ile Asp Glu Asn Lys Ile Ala 
        35                  40                  45              


Thr Thr Gly Glu Ala Asn Glu Leu Leu His Thr Phe Leu Arg Trp Lys 
    50                  55                  60                  


Thr Ser Tyr Leu Val Leu Arg Pro His Asp Val Ala Phe Leu Leu Val 
65                  70                  75                  80  


Tyr Arg Glu Lys Ser Asn Tyr Val Gly Ala Thr Phe Gln Gly Lys Met 
                85                  90                  95      


Cys Asp Ala Asn Tyr Ala Gly Gly Val Val Leu His Pro Arg Thr Ile 
            100                 105                 110         


Ser Leu Glu Ser Leu Ala Val Ile Leu Ala Gln Leu Leu Ser Leu Ser 
        115                 120                 125             


Met Gly Ile Thr Tyr Asp Asp Ile Asn Lys Cys Gln Cys Ser Gly Ala 
    130                 135                 140                 


Val Cys Ile Met Asn Pro Glu Ala Ile His Phe Ser Gly Val Lys Ile 
145                 150                 155                 160 


Phe Ser Asn Cys Ser Phe Glu Asp Phe Ala His Phe Ile Ser Lys Gln 
                165                 170                 175     


Lys Ser Gln Cys Leu His Asn Gln Pro Arg Leu Asp Pro Phe Phe Lys 
            180                 185                 190         


Gln Gln Ala Val Cys Gly Asn Ala Lys Leu Glu Ala Gly Glu Glu Cys 
        195                 200                 205             


Asp Cys Gly Thr Glu Gln Asp Cys Ala Leu Ile Gly Glu Thr Cys Cys 
    210                 215                 220                 


Asp Ile Ala Thr Cys Arg Phe Lys Ala Gly Ser Asn Cys Ala Glu Gly 
225                 230                 235                 240 


Pro Cys Cys Glu Asn Cys Leu Phe Met Ser Lys Glu Arg Met Cys Arg 
                245                 250                 255     


Pro Ser Phe Glu Glu Cys Asp Leu Pro Glu Tyr Cys Asn Gly Ser Ser 
            260                 265                 270         


Ala Ser Cys Pro Glu Asn His Tyr Val Gln Thr Gly His Pro Cys Gly 
        275                 280                 285             


Leu Asn Gln Trp Ile Cys Ile Asp Gly Val Cys Met Ser Gly Asp Lys 
    290                 295                 300                 


Gln Cys Thr Asp Thr Phe Gly Lys Glu Val Glu Phe Gly Pro Ser Glu 
305                 310                 315                 320 


Cys Tyr Ser His Leu Asn Ser Lys Thr Asp Val Ser Gly Asn Cys Gly 
                325                 330                 335     


Ile Ser Asp Ser Gly Tyr Thr Gln Cys Glu Ala Asp Asn Leu Gln Cys 
            340                 345                 350         


Gly Lys Leu Ile Cys Lys Tyr Val Gly Lys Phe Leu Leu Gln Ile Pro 
        355                 360                 365             


Arg Ala Thr Ile Ile Tyr Ala Asn Ile Ser Gly His Leu Cys Ile Ala 
    370                 375                 380                 


Val Glu Phe Ala Ser Asp His Ala Asp Ser Gln Lys Met Trp Ile Lys 
385                 390                 395                 400 


Asp Gly Thr Ser Cys Gly Ser Asn Lys Val Cys Arg Asn Gln Arg Cys 
                405                 410                 415     


Val Ser Ser Ser Tyr Leu Gly Tyr Asp Cys Thr Thr Asp Lys Cys Asn 
            420                 425                 430         


Asp Arg Gly Val Cys Asn Asn Lys Lys His Cys His Cys Ser Ala Ser 
        435                 440                 445             


Tyr Leu Pro Pro Asp Cys Ser Val Gln Ser Asp Leu Trp Pro Gly Gly 
    450                 455                 460                 


Ser Ile Asp Ser Gly Asn Phe Pro Pro Val Ala Ile Pro Ala Arg Leu 
465                 470                 475                 480 


Pro Glu Arg Arg Tyr Ile Glu Asn Ile Tyr His Ser Lys Pro Met Arg 
                485                 490                 495     


<210>  12
<211>  487
<212>  PRT
<213>  Homo Sapiens

<400>  12

Arg Phe Val Glu Leu Val Val Val Val Asp Asn Ile Arg Tyr Leu Phe 
1               5                   10                  15      


Ser Gln Ser Asn Ala Thr Thr Val Gln His Glu Val Phe Asn Val Val 
            20                  25                  30          


Asn Ile Val Asp Ser Phe Tyr His Pro Leu Glu Val Asp Val Ile Leu 
        35                  40                  45              


Thr Gly Ile Asp Ile Trp Thr Ala Ser Asn Pro Leu Pro Thr Ser Gly 
    50                  55                  60                  


Asp Leu Asp Asn Val Leu Glu Asp Phe Ser Ile Trp Lys Asn Tyr Asn 
65                  70                  75                  80  


Leu Asn Asn Arg Leu Gln His Asp Val Ala His Leu Phe Ile Lys Asp 
                85                  90                  95      


Thr Gln Gly Met Lys Leu Gly Val Ala Tyr Val Lys Gly Ile Cys Gln 
            100                 105                 110         


Asn Pro Phe Asn Thr Gly Val Asp Val Phe Glu Asp Asn Arg Leu Val 
        115                 120                 125             


Val Phe Ala Ile Thr Leu Gly His Glu Leu Gly His Asn Leu Gly Met 
    130                 135                 140                 


Gln His Asp Thr Gln Trp Cys Val Cys Glu Leu Gln Trp Cys Ile Met 
145                 150                 155                 160 


His Ala Tyr Arg Lys Val Thr Thr Lys Phe Ser Asn Cys Ser Tyr Ala 
                165                 170                 175     


Gln Tyr Trp Asp Ser Thr Ile Ser Ser Gly Leu Cys Ile Gln Pro Pro 
            180                 185                 190         


Pro Tyr Pro Gly Asn Ile Phe Arg Leu Lys Tyr Cys Gly Asn Leu Val 
        195                 200                 205             


Val Glu Glu Gly Glu Glu Cys Asp Cys Gly Thr Ile Arg Gln Cys Ala 
    210                 215                 220                 


Lys Asp Pro Cys Cys Leu Leu Asn Cys Thr Leu His Pro Gly Ala Ala 
225                 230                 235                 240 


Cys Ala Phe Gly Ile Cys Cys Lys Asp Cys Lys Phe Leu Pro Ser Gly 
                245                 250                 255     


Thr Leu Cys Arg Gln Gln Val Gly Glu Cys Asp Leu Pro Glu Trp Cys 
            260                 265                 270         


Asn Gly Thr Ser His Gln Cys Pro Asp Asp Val Tyr Val Gln Asp Gly 
        275                 280                 285             


Ile Ser Cys Asn Val Asn Ala Phe Cys Tyr Glu Lys Thr Cys Asn Asn 
    290                 295                 300                 


His Asp Ile Gln Cys Lys Glu Ile Phe Gly Gln Asp Ala Arg Ser Ala 
305                 310                 315                 320 


Ser Gln Ser Cys Tyr Gln Glu Ile Asn Thr Gln Gly Asn Arg Phe Gly 
                325                 330                 335     


His Cys Gly Ile Val Gly Thr Thr Tyr Val Lys Cys Trp Thr Pro Asp 
            340                 345                 350         


Ile Met Cys Gly Arg Val Gln Cys Glu Asn Val Gly Val Ile Pro Asn 
        355                 360                 365             


Leu Ile Glu His Ser Thr Val Gln Gln Phe His Leu Asn Asp Thr Thr 
    370                 375                 380                 


Cys Trp Gly Thr Asp Tyr His Leu Gly Met Ala Ile Pro Asp Ile Gly 
385                 390                 395                 400 


Glu Val Lys Asp Gly Thr Val Cys Gly Pro Glu Lys Ile Cys Ile Arg 
                405                 410                 415     


Lys Lys Cys Ala Ser Met Val His Leu Ser Gln Ala Cys Gln Pro Lys 
            420                 425                 430         


Thr Cys Asn Met Arg Gly Ile Cys Asn Asn Lys Gln His Cys His Cys 
        435                 440                 445             


Asn His Glu Trp Ala Pro Pro Tyr Cys Lys Asp Lys Gly Tyr Gly Gly 
    450                 455                 460                 


Ser Ala Asp Ser Gly Pro Pro Pro Lys Asn Asn Met Glu Gly Leu Asn 
465                 470                 475                 480 


Val Met Gly Lys Leu Arg Tyr 
                485         


<210>  13
<211>  467
<212>  PRT
<213>  Homo Sapiens

<400>  13

Pro Lys Ser Ala Gly Asp Trp Trp Thr His Ala Trp Phe Leu Glu Leu 
1               5                   10                  15      


Val Val Val Val Asn His Asp Phe Phe Ile Tyr Ser Gln Ser Asn Ile 
            20                  25                  30          


Ser Lys Val Gln Glu Asp Val Phe Leu Val Val Asn Ile Val Asp Ser 
        35                  40                  45              


Met Tyr Gln Gln Leu Gly Thr Tyr Ile Ile Leu Ile Gly Ile Glu Ile 
    50                  55                  60                  


Trp Asn Gln Gly Asn Val Phe Pro Met Thr Ser Ile Glu Gln Val Leu 
65                  70                  75                  80  


Asn Asp Phe Ser Gln Trp Lys Gln Ile Ser Leu Ser Gln Leu Gln His 
                85                  90                  95      


Asp Ala Ala His Met Phe Ile Lys Asn Ser Leu Ile Ser Ile Leu Gly 
            100                 105                 110         


Leu Ala Tyr Val Ala Gly Ile Cys Arg Pro Pro Ile Asp Cys Gly Val 
        115                 120                 125             


Asp Asn Phe Gln Gly Asp Thr Trp Ser Leu Phe Ala Asn Thr Val Ala 
    130                 135                 140                 


His Glu Leu Gly His Thr Leu Gly Met Gln His Asp Glu Glu Phe Cys 
145                 150                 155                 160 


Phe Cys Gly Glu Arg Gly Cys Ile Met Asn Thr Phe Arg Val Pro Ala 
                165                 170                 175     


Glu Lys Phe Thr Asn Cys Ser Tyr Ala Asp Phe Met Lys Thr Thr Leu 
            180                 185                 190         


Asn Gln Gly Ser Cys Leu His Asn Pro Pro Arg Leu Gly Glu Ile Phe 
        195                 200                 205             


Met Leu Lys Arg Cys Gly Asn Gly Val Val Glu Arg Glu Glu Gln Cys 
    210                 215                 220                 


Asp Cys Gly Ser Val Gln Gln Cys Glu Gln Asp Ala Cys Cys Leu Leu 
225                 230                 235                 240 


Asn Cys Thr Leu Arg Pro Gly Ala Ala Cys Ala Phe Gly Leu Cys Cys 
                245                 250                 255     


Lys Asp Cys Lys Phe Met Pro Ser Gly Glu Leu Cys Arg Gln Glu Val 
            260                 265                 270         


Asn Glu Cys Asp Leu Pro Glu Trp Cys Asn Gly Thr Ser His Gln Cys 
        275                 280                 285             


Pro Glu Asp Arg Tyr Val Gln Asp Gly Ile Pro Cys Ser Asp Ser Ala 
    290                 295                 300                 


Tyr Cys Tyr Gln Lys Arg Cys Asn Asn His Asp Gln His Cys Arg Glu 
305                 310                 315                 320 


Ile Phe Gly Lys Asp Ala Lys Ser Ala Ser Gln Asn Cys Tyr Lys Glu 
                325                 330                 335     


Ile Asn Ser Gln Gly Asn Arg Phe Gly His Cys Gly Ile Asn Gly Thr 
            340                 345                 350         


Thr Tyr Leu Lys Cys His Ile Ser Asp Val Phe Cys Gly Arg Val Gln 
        355                 360                 365             


Cys Glu Asn Val Arg Asp Ile Pro Leu Leu Gln Asp His Phe Thr Leu 
    370                 375                 380                 


Gln His Thr His Ile Asn Gly Val Thr Cys Trp Gly Ile Asp Tyr His 
385                 390                 395                 400 


Leu Arg Met Asn Ile Ser Asp Ile Gly Glu Val Lys Asp Gly Thr Val 
                405                 410                 415     


Cys Gly Pro Gly Lys Ile Cys Ile His Lys Lys Cys Val Ser Leu Ser 
            420                 425                 430         


Val Leu Ser His Val Cys Leu Pro Glu Thr Cys Asn Met Lys Gly Ile 
        435                 440                 445             


Cys Asn Asn Lys His His Cys His Cys Gly Tyr Gly Trp Ser Pro Pro 
    450                 455                 460                 


Tyr Cys Gln 
465         


<210>  14
<211>  514
<212>  PRT
<213>  Homo Sapiens

<400>  14

Ser Lys Arg Gln Leu Arg Arg Tyr Pro Arg Asn Val Glu Glu Glu Thr 
1               5                   10                  15      


Lys Tyr Ile Glu Leu Met Ile Val Asn Asp His Leu Met Phe Lys Lys 
            20                  25                  30          


His Arg Leu Ser Val Val His Thr Asn Thr Tyr Ala Lys Ser Val Val 
        35                  40                  45              


Asn Met Ala Asp Leu Ile Tyr Lys Asp Gln Leu Lys Thr Arg Ile Val 
    50                  55                  60                  


Leu Val Ala Met Glu Thr Trp Ala Thr Asp Asn Lys Phe Ala Ile Ser 
65                  70                  75                  80  


Glu Asn Pro Leu Ile Thr Leu Arg Glu Phe Met Lys Tyr Arg Arg Asp 
                85                  90                  95      


Phe Ile Lys Glu Lys Ser Asp Ala Val His Leu Phe Ser Gly Ser Gln 
            100                 105                 110         


Phe Glu Ser Ser Arg Ser Gly Ala Ala Tyr Ile Gly Gly Ile Cys Ser 
        115                 120                 125             


Leu Leu Lys Gly Gly Gly Val Asn Glu Phe Gly Lys Thr Asp Leu Met 
    130                 135                 140                 


Ala Val Thr Leu Ala Gln Ser Leu Ala His Asn Ile Gly Ile Ile Ser 
145                 150                 155                 160 


Asp Lys Arg Lys Leu Ala Ser Gly Glu Cys Lys Cys Glu Asp Thr Trp 
                165                 170                 175     


Ser Gly Cys Ile Met Gly Asp Thr Gly Tyr Tyr Leu Pro Lys Lys Phe 
            180                 185                 190         


Thr Gln Cys Asn Ile Glu Glu Tyr His Asp Phe Leu Asn Ser Gly Gly 
        195                 200                 205             


Gly Ala Cys Leu Phe Asn Lys Pro Ser Lys Leu Leu Asp Pro Pro Glu 
    210                 215                 220                 


Cys Gly Asn Gly Phe Ile Glu Thr Gly Glu Glu Cys Asp Cys Gly Thr 
225                 230                 235                 240 


Pro Ala Glu Cys Val Leu Glu Gly Ala Glu Cys Cys Lys Lys Cys Thr 
                245                 250                 255     


Leu Thr Gln Asp Ser Gln Cys Ser Asp Gly Leu Cys Cys Lys Lys Cys 
            260                 265                 270         


Lys Phe Gln Pro Met Gly Thr Val Cys Arg Glu Ala Val Asn Asp Cys 
        275                 280                 285             


Asp Ile Arg Glu Thr Cys Ser Gly Asn Ser Ser Gln Cys Ala Pro Asn 
    290                 295                 300                 


Ile His Lys Met Asp Gly Tyr Ser Cys Asp Gly Val Gln Gly Ile Cys 
305                 310                 315                 320 


Phe Gly Gly Arg Cys Lys Thr Arg Asp Arg Gln Cys Lys Tyr Ile Trp 
                325                 330                 335     


Gly Gln Lys Val Thr Ala Ser Asp Lys Tyr Cys Tyr Glu Lys Leu Asn 
            340                 345                 350         


Ile Glu Gly Thr Glu Lys Gly Asn Cys Gly Lys Asp Lys Asp Thr Trp 
        355                 360                 365             


Ile Gln Cys Asn Lys Arg Asp Val Leu Cys Gly Tyr Leu Leu Cys Thr 
    370                 375                 380                 


Asn Ile Gly Asn Ile Pro Arg Leu Gly Glu Leu Asp Gly Glu Ile Thr 
385                 390                 395                 400 


Ser Thr Leu Val Val Gln Gln Gly Arg Thr Leu Asn Cys Ser Gly Gly 
                405                 410                 415     


His Val Lys Leu Glu Glu Asp Val Asp Leu Gly Tyr Val Glu Asp Gly 
            420                 425                 430         


Thr Pro Cys Gly Pro Gln Met Met Cys Leu Glu His Arg Cys Leu Pro 
        435                 440                 445             


Val Ala Ser Phe Asn Phe Ser Thr Cys Leu Ser Ser Lys Glu Gly Thr 
    450                 455                 460                 


Ile Cys Ser Gly Asn Gly Val Cys Ser Asn Glu Leu Lys Cys Val Cys 
465                 470                 475                 480 


Asn Arg His Trp Ile Gly Ser Asp Cys Asn Thr Tyr Phe Pro His Asn 
                485                 490                 495     


Asp Asp Ala Lys Thr Gly Ile Thr Leu Ser Gly Asn Gly Val Ala Gly 
            500                 505                 510         


Thr Asn 
        


<210>  15
<211>  506
<212>  PRT
<213>  Homo Sapiens

<400>  15

Ala Val Asn Pro Ser Arg Gly Ile Phe Glu Glu Met Lys Tyr Leu Glu 
1               5                   10                  15      


Leu Met Ile Val Asn Asp His Lys Thr Tyr Lys Lys His Arg Ser Ser 
            20                  25                  30          


His Ala His Thr Asn Asn Phe Ala Lys Ser Val Val Asn Leu Val Asp 
        35                  40                  45              


Ser Ile Tyr Lys Glu Gln Leu Asn Thr Arg Val Val Leu Val Ala Val 
    50                  55                  60                  


Glu Thr Trp Thr Glu Lys Asp Gln Ile Asp Ile Thr Thr Asn Pro Val 
65                  70                  75                  80  


Gln Met Leu His Glu Phe Ser Lys Tyr Arg Gln Arg Ile Lys Gln His 
                85                  90                  95      


Ala Asp Ala Val His Leu Ile Ser Arg Val Thr Phe His Tyr Lys Arg 
            100                 105                 110         


Ser Ser Leu Ser Tyr Phe Gly Gly Val Cys Ser Arg Thr Arg Gly Val 
        115                 120                 125             


Gly Val Asn Glu Tyr Gly Leu Pro Met Ala Val Ala Gln Val Leu Ser 
    130                 135                 140                 


Gln Ser Leu Ala Gln Asn Leu Gly Ile Gln Trp Glu Pro Ser Ser Arg 
145                 150                 155                 160 


Lys Pro Lys Cys Asp Cys Thr Glu Ser Trp Gly Gly Cys Ile Met Glu 
                165                 170                 175     


Glu Thr Gly Val Ser His Ser Arg Lys Phe Ser Lys Cys Ser Ile Leu 
            180                 185                 190         


Glu Tyr Arg Asp Phe Leu Gln Arg Gly Gly Gly Ala Cys Leu Phe Asn 
        195                 200                 205             


Arg Pro Thr Lys Leu Phe Glu Pro Thr Glu Cys Gly Asn Gly Tyr Val 
    210                 215                 220                 


Glu Ala Gly Glu Glu Cys Asp Cys Gly Phe His Val Glu Cys Tyr Gly 
225                 230                 235                 240 


Leu Cys Cys Lys Lys Cys Ser Leu Ser Asn Gly Ala His Cys Ser Asp 
                245                 250                 255     


Gly Pro Cys Cys Asn Asn Thr Ser Cys Leu Phe Gln Pro Arg Gly Tyr 
            260                 265                 270         


Glu Cys Arg Asp Ala Val Asn Glu Cys Asp Ile Thr Glu Tyr Cys Thr 
        275                 280                 285             


Gly Asp Ser Gly Gln Cys Pro Pro Asn Leu His Lys Gln Asp Gly Tyr 
    290                 295                 300                 


Ala Cys Asn Gln Asn Gln Gly Arg Cys Tyr Asn Gly Glu Cys Lys Thr 
305                 310                 315                 320 


Arg Asp Asn Gln Cys Gln Tyr Ile Trp Gly Thr Lys Ala Ala Gly Ser 
                325                 330                 335     


Asp Lys Phe Cys Tyr Glu Lys Leu Asn Thr Glu Gly Thr Glu Lys Gly 
            340                 345                 350         


Asn Cys Gly Lys Asp Gly Asp Arg Trp Ile Gln Cys Ser Lys His Asp 
        355                 360                 365             


Val Phe Cys Gly Phe Leu Leu Cys Thr Asn Leu Thr Arg Ala Pro Arg 
    370                 375                 380                 


Ile Gly Gln Leu Gln Gly Glu Ile Ile Pro Thr Ser Phe Tyr His Gln 
385                 390                 395                 400 


Gly Arg Val Ile Asp Cys Ser Gly Ala His Val Val Leu Asp Asp Asp 
                405                 410                 415     


Thr Asp Val Gly Tyr Val Glu Asp Gly Thr Pro Cys Gly Pro Ser Met 
            420                 425                 430         


Met Cys Leu Asp Arg Lys Cys Leu Gln Ile Gln Ala Leu Asn Met Ser 
        435                 440                 445             


Ser Cys Pro Leu Asp Ser Lys Gly Lys Val Cys Ser Gly His Gly Val 
    450                 455                 460                 


Cys Ser Asn Glu Ala Thr Cys Ile Cys Asp Phe Thr Trp Ala Gly Thr 
465                 470                 475                 480 


Asp Cys Ser Ile Arg Asp Pro Val Arg Asn Leu His Pro Pro Lys Asp 
                485                 490                 495     


Glu Gly Pro Lys Gly Pro Ser Ala Thr Asn 
            500                 505     


<210>  16
<211>  467
<212>  PRT
<213>  Homo Sapiens

<400>  16

Val Gln Glu His Glu Lys Tyr Ile Glu Tyr Tyr Leu Val Leu Asp Asn 
1               5                   10                  15      


Gly Glu Phe Lys Arg Tyr Asn Glu Asn Gln Asp Glu Ile Arg Lys Arg 
            20                  25                  30          


Val Phe Glu Met Ala Asn Tyr Val Asn Met Leu Tyr Lys Lys Leu Asn 
        35                  40                  45              


Thr His Val Ala Leu Val Gly Met Glu Ile Trp Thr Asp Lys Asp Lys 
    50                  55                  60                  


Ile Lys Ile Thr Pro Asn Ala Ser Phe Thr Leu Glu Asn Phe Ser Lys 
65                  70                  75                  80  


Trp Arg Gly Ser Val Leu Ser Arg Arg Lys Arg His Asp Ile Ala Gln 
                85                  90                  95      


Leu Ile Thr Ala Thr Glu Leu Ala Gly Thr Thr Val Gly Leu Ala Phe 
            100                 105                 110         


Met Ser Thr Met Cys Ser Pro Tyr Ser Val Gly Val Val Gln Asp His 
        115                 120                 125             


Ser Asp Asn Leu Leu Arg Val Ala Gly Thr Met Ala His Glu Met Gly 
    130                 135                 140                 


His Asn Phe Gly Met Phe His Asp Asp Tyr Ser Cys Lys Cys Pro Ser 
145                 150                 155                 160 


Thr Ile Cys Val Met Asp Lys Ala Leu Ser Phe Tyr Ile Pro Thr Asp 
                165                 170                 175     


Phe Ser Ser Cys Ser Arg Leu Ser Tyr Asp Lys Phe Phe Glu Asp Lys 
            180                 185                 190         


Leu Ser Asn Cys Leu Phe Asn Ala Pro Leu Pro Thr Asp Ile Ile Ser 
        195                 200                 205             


Thr Pro Ile Cys Gly Asn Gln Leu Val Glu Met Gly Glu Asp Cys Asp 
    210                 215                 220                 


Cys Gly Thr Ser Glu Glu Cys Thr Asn Ile Cys Cys Asp Ala Lys Thr 
225                 230                 235                 240 


Cys Lys Ile Lys Ala Thr Phe Gln Cys Ala Leu Gly Glu Cys Cys Glu 
                245                 250                 255     


Lys Cys Gln Phe Lys Lys Ala Gly Met Val Cys Arg Pro Ala Lys Asp 
            260                 265                 270         


Glu Cys Asp Leu Pro Glu Met Cys Asn Gly Lys Ser Gly Asn Cys Pro 
        275                 280                 285             


Asp Asp Arg Phe Gln Val Asn Gly Phe Pro Cys His His Gly Lys Gly 
    290                 295                 300                 


His Cys Leu Met Gly Thr Cys Pro Thr Leu Gln Glu Gln Cys Thr Glu 
305                 310                 315                 320 


Leu Trp Gly Pro Gly Thr Glu Val Ala Asp Lys Ser Cys Tyr Asn Arg 
                325                 330                 335     


Asn Glu Gly Gly Ser Lys Tyr Gly Tyr Cys Arg Arg Val Asp Asp Thr 
            340                 345                 350         


Leu Ile Pro Cys Lys Ala Asn Asp Thr Met Cys Gly Lys Leu Phe Cys 
        355                 360                 365             


Gln Gly Gly Ser Asp Asn Leu Pro Trp Lys Gly Arg Ile Val Thr Phe 
    370                 375                 380                 


Leu Thr Cys Lys Thr Phe Asp Pro Glu Asp Thr Ser Gln Glu Ile Gly 
385                 390                 395                 400 


Met Val Ala Asn Gly Thr Lys Cys Gly Asp Asn Lys Val Cys Ile Asn 
                405                 410                 415     


Ala Glu Cys Val Asp Ile Glu Lys Ala Tyr Lys Ser Thr Asn Cys Ser 
            420                 425                 430         


Ser Lys Cys Lys Gly His Ala Val Cys Asp His Glu Leu Gln Cys Gln 
        435                 440                 445             


Cys Glu Glu Gly Trp Ile Pro Pro Asp Cys Asp Asp Ser Ser Val Val 
    450                 455                 460                 


Phe His Phe 
465         


<210>  17
<211>  481
<212>  PRT
<213>  Homo Sapiens

<400>  17

Trp Ile His Phe Arg Ile Val Glu Ile Val Val Val Ile Asp Asn Tyr 
1               5                   10                  15      


Leu Tyr Ile Arg Tyr Glu Arg Asn Asp Ser Lys Leu Leu Glu Asp Leu 
            20                  25                  30          


Tyr Val Ile Val Asn Ile Val Asp Ser Ile Leu Asp Val Ile Gly Val 
        35                  40                  45              


Lys Val Leu Leu Phe Gly Leu Glu Ile Trp Thr Asn Lys Asn Leu Ile 
    50                  55                  60                  


Val Val Asp Asp Val Arg Lys Ser Val His Leu Tyr Cys Lys Trp Lys 
65                  70                  75                  80  


Ser Glu Asn Ile Thr Pro Arg Met Gln His Asp Thr Ser His Leu Phe 
                85                  90                  95      


Thr Thr Leu Gly Leu Arg Gly Leu Ser Gly Ile Gly Ala Phe Arg Gly 
            100                 105                 110         


Met Cys Thr Pro His Arg Ser Cys Ala Ile Val Thr Phe Met Asn Lys 
        115                 120                 125             


Thr Leu Gly Thr Phe Ser Ile Ala Val Ala His His Leu Gly His Asn 
    130                 135                 140                 


Leu Gly Met Asn His Asp Glu Asp Thr Cys Arg Cys Ser Gln Pro Arg 
145                 150                 155                 160 


Cys Ile Met His Glu Gly Asn Pro Pro Ile Thr Lys Phe Ser Asn Cys 
                165                 170                 175     


Ser Tyr Gly Asp Phe Trp Glu Tyr Thr Val Glu Arg Thr Lys Cys Leu 
            180                 185                 190         


Leu Glu Thr Val His Thr Lys Asp Ile Phe Asn Val Lys Arg Cys Gly 
        195                 200                 205             


Asn Gly Val Val Glu Glu Gly Glu Glu Cys Asp Cys Gly Pro Leu Lys 
    210                 215                 220                 


His Cys Ala Lys Asp Pro Cys Cys Leu Ser Asn Cys Thr Leu Thr Asp 
225                 230                 235                 240 


Gly Ser Thr Cys Ala Phe Gly Leu Cys Cys Lys Asp Cys Lys Phe Leu 
                245                 250                 255     


Pro Ser Gly Lys Val Cys Arg Lys Glu Val Asn Glu Cys Asp Leu Pro 
            260                 265                 270         


Glu Trp Cys Asn Gly Thr Ser His Lys Cys Pro Asp Asp Phe Tyr Val 
        275                 280                 285             


Glu Asp Gly Ile Pro Cys Lys Glu Arg Gly Tyr Cys Tyr Glu Lys Ser 
    290                 295                 300                 


Cys His Asp Arg Asn Glu Gln Cys Arg Arg Ile Phe Gly Ala Gly Ala 
305                 310                 315                 320 


Asn Thr Ala Ser Glu Thr Cys Tyr Lys Glu Leu Asn Thr Leu Gly Asp 
                325                 330                 335     


Arg Val Gly His Cys Gly Ile Lys Asn Ala Thr Tyr Ile Lys Cys Asn 
            340                 345                 350         


Ile Ser Asp Val Gln Cys Gly Arg Ile Gln Cys Glu Asn Val Thr Glu 
        355                 360                 365             


Ile Pro Asn Met Ser Asp His Thr Thr Val His Trp Ala Arg Phe Asn 
    370                 375                 380                 


Asp Ile Met Cys Trp Ser Thr Asp Tyr His Leu Gly Met Lys Gly Pro 
385                 390                 395                 400 


Asp Ile Gly Glu Val Lys Asp Gly Thr Glu Cys Gly Ile Asp His Ile 
                405                 410                 415     


Cys Ile His Arg His Cys Val His Ile Thr Ile Leu Asn Ser Asn Cys 
            420                 425                 430         


Ser Pro Ala Phe Cys Asn Lys Arg Gly Ile Cys Asn Asn Lys His His 
        435                 440                 445             


Cys His Cys Asn Tyr Leu Trp Asp Pro Pro Asn Cys Leu Ile Lys Gly 
    450                 455                 460                 


Tyr Gly Gly Ser Val Asp Ser Gly Pro Pro Pro Lys Arg Lys Lys Lys 
465                 470                 475                 480 


Lys 
    


<210>  18
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  18

Tyr Lys His Pro Lys Tyr Leu Glu Leu Ile Leu Leu Phe Asp Gln Ser 
1               5                   10                  15      


Arg Tyr Arg Phe Val Asn Asn Asn Leu Ser Gln Val Ile His Asp Ala 
            20                  25                  30          


Ile Leu Leu Thr Gly Ile Met Asp Thr Tyr Phe Gln Asp Val Arg Met 
        35                  40                  45              


Arg Ile His Leu Lys Ala Leu Glu Val Trp Thr Asp Phe Asn Lys Ile 
    50                  55                  60                  


Arg Val Gly Tyr Pro Glu Leu Ala Glu Val Leu Gly Arg Phe Val Ile 
65                  70                  75                  80  


Tyr Lys Lys Ser Val Leu Asn Ala Arg Leu Ser Ser Asp Trp Ala His 
                85                  90                  95      


Leu Tyr Leu Gln Arg Lys Tyr Asn Asp Ala Leu Ala Trp Ser Phe Gly 
            100                 105                 110         


Lys Val Cys Ser Leu Glu Tyr Ala Gly Ser Val Ser Thr Leu Leu Asp 
        115                 120                 125             


Thr Asn Ile Leu Ala Pro Ala Thr Trp Ser Ala His Glu Leu Gly His 
    130                 135                 140                 


Ala Val Gly Met Ser His Asp Glu Gln Tyr Cys Gln Cys Arg Gly Arg 
145                 150                 155                 160 


Leu Asn Cys Ile Met Gly Ser Gly Arg Thr Gly Phe Ser Asn Cys Ser 
                165                 170                 175     


Tyr Ile Ser Phe Phe Lys His Ile Ser Ser Gly Ala Thr Cys Leu Asn 
            180                 185                 190         


Asn Ile Pro Gly Leu Gly Tyr Val Leu Lys Arg Cys Gly Asn Lys Ile 
        195                 200                 205             


Val Glu Asp Asn Glu Glu Cys Asp Cys Gly Ser Thr Glu Glu Cys Gln 
    210                 215                 220                 


Lys Asp Arg Cys Cys Gln Ser Asn Cys Lys Leu Gln Pro Gly Ala Asn 
225                 230                 235                 240 


Cys Ser Ile Gly Leu Cys Cys His Asp Cys Arg Phe Arg Pro Ser Gly 
                245                 250                 255     


Tyr Val Cys Arg Gln Glu Gly Asn Glu Cys Asp Leu Ala Glu Tyr Cys 
            260                 265                 270         


Asp Gly Asn Ser Ser Ser Cys Pro Asn Asp Val Tyr Lys Gln Asp Gly 
        275                 280                 285             


Thr Pro Cys Lys Tyr Glu Gly Arg Cys Phe Arg Lys Gly Cys Arg Ser 
    290                 295                 300                 


Arg Tyr Met Gln Cys Gln Ser Ile Phe Gly Pro Asp Ala Met Glu Ala 
305                 310                 315                 320 


Pro Ser Glu Cys Tyr Asp Ala Val Asn Leu Ile Gly Asp Gln Phe Gly 
                325                 330                 335     


Asn Cys Glu Ile Thr Gly Ile Arg Asn Phe Lys Lys Cys Glu Ser Ala 
            340                 345                 350         


Asn Ser Ile Cys Gly Arg Leu Gln Cys Ile Asn Val Glu Thr Ile Pro 
        355                 360                 365             


Asp Leu Pro Glu His Thr Thr Ile Ile Ser Thr His Leu Gln Ala Glu 
    370                 375                 380                 


Asn Leu Met Cys Trp Gly Thr Gly Tyr His Leu Ser Met Lys Pro Met 
385                 390                 395                 400 


Gly Ile Pro Asp Leu Gly Met Ile Asn Asp Gly Thr Ser Cys Gly Glu 
                405                 410                 415     


Gly Arg Val Cys Phe Lys Lys Asn Cys Val Asn Ser Ser Val Leu Gln 
            420                 425                 430         


Phe Asp Cys Leu Pro Glu Lys Cys Asn Thr Arg Gly Val Cys Asn Asn 
        435                 440                 445             


Arg Lys Asn Cys His Cys Met Tyr Gly Trp Ala Pro Pro Phe Cys Glu 
    450                 455                 460                 


Glu Val Gly Tyr Gly Gly Ser Ile Asp Ser Gly Pro Pro Gly Leu Leu 
465                 470                 475                 480 


Arg Gly Ala Ile Pro Ser Ser Ile Trp 
                485                 


<210>  19
<211>  508
<212>  PRT
<213>  Homo Sapiens

<400>  19

Lys Ser Glu Pro Ala Val Pro Asp Leu Phe Pro Leu Tyr Leu Glu Met 
1               5                   10                  15      


His Ile Val Val Asp Lys Thr Leu Tyr Asp Tyr Trp Gly Ser Asp Ser 
            20                  25                  30          


Met Ile Val Thr Asn Lys Val Ile Glu Ile Val Gly Leu Ala Asn Ser 
        35                  40                  45              


Met Phe Thr Gln Phe Lys Val Thr Ile Val Leu Ser Ser Leu Glu Leu 
    50                  55                  60                  


Trp Ser Asp Glu Asn Lys Ile Ser Thr Val Gly Glu Ala Asp Glu Leu 
65                  70                  75                  80  


Leu Gln Lys Phe Leu Glu Trp Lys Gln Ser Tyr Leu Asn Leu Arg Pro 
                85                  90                  95      


His Asp Ile Ala Tyr Leu Leu Ile Tyr Met Asp Tyr Pro Arg Tyr Leu 
            100                 105                 110         


Gly Ala Val Phe Pro Gly Thr Met Cys Ile Thr Arg Tyr Ser Ala Gly 
        115                 120                 125             


Val Ala Leu Tyr Pro Lys Glu Ile Thr Leu Glu Ala Phe Ala Val Ile 
    130                 135                 140                 


Val Thr Gln Met Leu Ala Leu Ser Leu Gly Ile Ser Tyr Asp Asp Pro 
145                 150                 155                 160 


Lys Lys Cys Gln Cys Ser Glu Ser Thr Cys Ile Met Asn Pro Glu Val 
                165                 170                 175     


Val Gln Ser Asn Gly Val Lys Thr Phe Ser Ser Cys Ser Leu Arg Ser 
            180                 185                 190         


Phe Gln Asn Phe Ile Ser Asn Val Gly Val Lys Cys Leu Gln Asn Lys 
        195                 200                 205             


Pro Gln Met Gln Lys Lys Ser Pro Lys Pro Val Cys Gly Asn Gly Arg 
    210                 215                 220                 


Leu Glu Gly Asn Glu Ile Cys Asp Cys Gly Thr Glu Ala Gln Cys Gly 
225                 230                 235                 240 


Pro Ala Ser Cys Cys Asp Phe Arg Thr Cys Val Leu Lys Asp Gly Ala 
                245                 250                 255     


Lys Cys Tyr Lys Gly Leu Cys Cys Lys Asp Cys Gln Ile Leu Gln Ser 
            260                 265                 270         


Gly Val Glu Cys Arg Pro Lys Ala His Pro Glu Cys Asp Ile Ala Glu 
        275                 280                 285             


Asn Cys Asn Gly Ser Ser Pro Glu Cys Gly Pro Asp Ile Thr Leu Ile 
    290                 295                 300                 


Asn Gly Leu Ser Cys Lys Asn Asn Lys Phe Ile Cys Tyr Asp Gly Asp 
305                 310                 315                 320 


Cys His Asp Leu Asp Ala Arg Cys Glu Ser Val Phe Gly Lys Gly Ser 
                325                 330                 335     


Arg Asn Ala Pro Phe Ala Cys Tyr Glu Glu Ile Gln Ser Gln Ser Asp 
            340                 345                 350         


Arg Phe Gly Asn Cys Gly Arg Asp Arg Asn Asn Lys Tyr Val Phe Cys 
        355                 360                 365             


Gly Trp Arg Asn Leu Ile Cys Gly Arg Leu Val Cys Thr Tyr Pro Thr 
    370                 375                 380                 


Arg Lys Pro Phe His Gln Glu Asn Gly Asp Val Ile Tyr Ala Phe Val 
385                 390                 395                 400 


Arg Asp Ser Val Cys Ile Thr Val Asp Tyr Lys Leu Pro Arg Thr Val 
                405                 410                 415     


Pro Asp Pro Leu Ala Val Lys Asn Gly Ser Gln Cys Asp Ile Gly Arg 
            420                 425                 430         


Val Cys Val Asn Arg Glu Cys Val Glu Ser Arg Ile Ile Lys Ala Ser 
        435                 440                 445             


Ala His Val Cys Ser Gln Gln Cys Ser Gly His Gly Val Cys Asp Ser 
    450                 455                 460                 


Arg Asn Lys Cys His Cys Ser Pro Gly Tyr Lys Pro Pro Asn Cys Gln 
465                 470                 475                 480 


Ile Arg Ser Lys Gly Phe Ser Ile Phe Pro Glu Glu Asp Met Gly Ser 
                485                 490                 495     


Ile Met Glu Arg Ala Ser Gly Lys Thr Glu Asn Thr 
            500                 505             


<210>  20
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  20

Glu Ala Arg Arg Thr Arg Lys Tyr Leu Glu Leu Tyr Ile Val Ala Asp 
1               5                   10                  15      


His Thr Leu Phe Leu Thr Arg His Arg Asn Leu Asn His Thr Lys Gln 
            20                  25                  30          


Arg Leu Leu Glu Val Ala Asn Tyr Val Asp Gln Leu Leu Arg Thr Leu 
        35                  40                  45              


Asp Ile Gln Val Ala Leu Thr Gly Leu Glu Val Trp Thr Glu Arg Asp 
    50                  55                  60                  


Arg Ser Arg Arg Gln Leu Arg Ala Phe Phe Arg Lys Gly Gly Gly Ala 
65                  70                  75                  80  


Cys Leu Ser Asn Ala Pro Asp Pro Gly Leu Pro Val Pro Pro Ala Leu 
                85                  90                  95      


Cys Gly Asn Gly Phe Val Glu Ala Gly Glu Glu Cys Asp Cys Gly Pro 
            100                 105                 110         


Gly Gln Glu Cys Arg Asp Leu Cys Cys Phe Ala His Asn Cys Ser Leu 
        115                 120                 125             


Arg Pro Gly Ala Gln Cys Ala His Gly Asp Cys Cys Val Arg Cys Leu 
    130                 135                 140                 


Leu Lys Pro Ala Gly Ala Leu Cys Arg Gln Ala Met Gly Asp Cys Asp 
145                 150                 155                 160 


Leu Pro Glu Phe Cys Thr Gly Thr Ser Ser His Cys Pro Pro Asp Val 
                165                 170                 175     


Tyr Leu Leu Asp Gly Ser Pro Cys Ala Arg Gly Ser Gly Tyr Cys Trp 
            180                 185                 190         


Asp Gly Ala Cys Pro Thr Leu Glu Gln Gln Cys Gln Gln Leu Trp Gly 
        195                 200                 205             


Pro Gly Ser His Pro Ala Pro Glu Ala Cys Phe Gln Val Val Asn Ser 
    210                 215                 220                 


Ala Gly Asp Ala His Gly Asn Cys Gly Gln Asp Ser Glu Gly His Phe 
225                 230                 235                 240 


Leu Pro Cys Ala Gly Arg Asp Ala Leu Cys Gly Lys Leu Gln Cys Gln 
                245                 250                 255     


Gly Gly Lys Pro Ser Leu Leu Ala Pro His Met Val Pro Val Asp Ser 
            260                 265                 270         


Thr Val His Leu Asp Gly Gln Glu Val Thr Cys Arg Gly Ala Leu Ala 
        275                 280                 285             


Leu Pro Ser Ala Gln Leu Asp Leu Leu Gly Leu Gly Leu Val Glu Pro 
    290                 295                 300                 


Gly Thr Gln Cys Gly Pro Arg Met Val Cys Gln Ser Arg Arg Cys Arg 
305                 310                 315                 320 


Lys Asn Ala Phe Gln Glu Leu Gln Arg Cys Leu Thr Ala Cys His Ser 
                325                 330                 335     


His Gly Val Cys Asn Ser Asn His Asn Cys His Cys Ala Pro Gly Trp 
            340                 345                 350         


Ala Pro Pro Phe Cys Asp Lys Pro Gly Phe Gly Gly Ser Met Asp Ser 
        355                 360                 365             


Gly Pro Val Gln Ala Glu Asn His Asp Thr Phe Leu Leu Ala Met Leu 
    370                 375                 380                 


Leu Ser Val Leu Leu Pro Leu Leu Pro Gly Ala Gly Leu Ala Trp Cys 
385                 390                 395                 400 


Cys Tyr Arg Leu Pro Gly Ala His Leu Gln Arg Cys Ser Trp Gly Cys 
                405                 410                 415     


Arg Arg Asp Pro Ala Cys Ser Gly Pro Lys Asp Gly Pro His Arg Asp 
            420                 425                 430         


His Pro Leu Gly Gly Val His Pro Met Glu Leu Gly Pro Thr Ala Thr 
        435                 440                 445             


Gly Gln Pro Trp Pro Leu Asp Pro Glu Asn Ser His Glu Pro Ser Ser 
    450                 455                 460                 


His Pro Glu Lys Pro Leu Pro Ala Val Ser Pro Asp Pro Gln Asp Gln 
465                 470                 475                 480 


Val Gln Met Pro Arg Ser Cys Leu Trp 
                485                 


<210>  21
<211>  639
<212>  PRT
<213>  Homo Sapiens

<400>  21

Ile Ala Pro Ser Arg Pro Trp Ala Leu Met Glu Gln Tyr Glu Val Val 
1               5                   10                  15      


Leu Pro Arg Arg Leu Pro Gly Pro Arg Val Arg Arg Ala Leu Pro Ser 
            20                  25                  30          


His Leu Gly Leu His Pro Glu Arg Val Ser Tyr Val Leu Gly Ala Thr 
        35                  40                  45              


Gly His Asn Phe Thr Leu His Leu Arg Lys Asn Arg Asp Leu Leu Gly 
    50                  55                  60                  


Ser Gly Tyr Thr Glu Thr Tyr Thr Ala Ala Asn Gly Ser Glu Val Thr 
65                  70                  75                  80  


Glu Gln Pro Arg Gly Gln Asp His Cys Phe Tyr Gln Gly His Val Glu 
                85                  90                  95      


Gly Tyr Pro Asp Ser Ala Ala Ser Leu Ser Thr Cys Ala Gly Leu Arg 
            100                 105                 110         


Gly Phe Phe Gln Val Gly Ser Asp Leu His Leu Ile Glu Pro Leu Asp 
        115                 120                 125             


Glu Gly Gly Glu Gly Gly Arg His Ala Val Tyr Gln Ala Glu His Leu 
    130                 135                 140                 


Leu Gln Thr Ala Gly Thr Cys Gly Val Ser Asp Asp Ser Leu Gly Ser 
145                 150                 155                 160 


Leu Leu Gly Pro Arg Thr Ala Ala Val Phe Arg Pro Arg Pro Gly Asp 
                165                 170                 175     


Ser Leu Pro Ser Arg Glu Thr Arg Tyr Val Glu Leu Tyr Val Val Val 
            180                 185                 190         


Asp Asn Ala Glu Phe Gln Met Leu Gly Ser Glu Ala Ala Val Arg His 
        195                 200                 205             


Arg Val Leu Glu Val Val Asn His Val Asp Lys Leu Tyr Gln Lys Leu 
    210                 215                 220                 


Asn Phe Arg Val Val Leu Val Gly Leu Glu Ile Trp Asn Ser Gln Asp 
225                 230                 235                 240 


Arg Phe His Val Ser Pro Asp Pro Ser Val Thr Leu Glu Asn Leu Leu 
                245                 250                 255     


Thr Trp Gln Ala Arg Gln Arg Thr Arg Arg His Leu His Asp Asn Val 
            260                 265                 270         


Gln Leu Ile Thr Gly Val Asp Phe Thr Gly Thr Thr Val Gly Phe Ala 
        275                 280                 285             


Arg Val Ser Ala Met Cys Ser His Ser Ser Gly Ala Val Asn Gln Asp 
    290                 295                 300                 


His Ser Lys Asn Pro Val Gly Val Ala Cys Thr Met Ala His Glu Met 
305                 310                 315                 320 


Gly His Asn Leu Gly Met Asp His Asp Glu Asn Val Gln Gly Cys Arg 
                325                 330                 335     


Cys Gln Glu Arg Phe Glu Ala Gly Arg Cys Ile Met Ala Gly Ser Ile 
            340                 345                 350         


Gly Ser Ser Phe Pro Arg Met Phe Ser Asp Cys Ser Gln Ala Tyr Leu 
        355                 360                 365             


Glu Ser Phe Leu Glu Arg Pro Gln Ser Val Cys Leu Ala Asn Ala Pro 
    370                 375                 380                 


Asp Leu Ser His Leu Val Gly Gly Pro Val Cys Gly Asn Leu Phe Val 
385                 390                 395                 400 


Glu Arg Gly Glu Gln Cys Asp Cys Gly Pro Pro Glu Asp Cys Arg Asn 
                405                 410                 415     


Arg Cys Cys Asn Ser Thr Thr Cys Gln Leu Ala Glu Gly Ala Gln Cys 
            420                 425                 430         


Ala His Gly Thr Cys Cys Gln Glu Cys Lys Val Lys Pro Ala Gly Glu 
        435                 440                 445             


Leu Cys Arg Pro Lys Lys Asp Met Cys Asp Leu Glu Glu Phe Cys Asp 
    450                 455                 460                 


Gly Arg His Pro Glu Cys Pro Glu Asp Ala Phe Gln Glu Asn Gly Thr 
465                 470                 475                 480 


Pro Cys Ser Gly Gly Tyr Cys Tyr Asn Gly Ala Cys Pro Thr Leu Ala 
                485                 490                 495     


Gln Gln Cys Gln Ala Phe Trp Gly Pro Gly Gly Gln Ala Ala Glu Glu 
            500                 505                 510         


Ser Cys Phe Ser Tyr Asp Ile Leu Pro Gly Cys Lys Ala Ser Arg Tyr 
        515                 520                 525             


Arg Ala Asp Met Cys Gly Val Leu Gln Cys Lys Gly Gly Gln Gln Pro 
    530                 535                 540                 


Leu Gly Arg Ala Ile Cys Ile Val Asp Val Cys His Ala Leu Thr Thr 
545                 550                 555                 560 


Glu Asp Gly Thr Ala Tyr Glu Pro Val Pro Glu Gly Thr Arg Cys Gly 
                565                 570                 575     


Pro Glu Lys Val Cys Trp Lys Gly Arg Cys Gln Asp Leu His Val Tyr 
            580                 585                 590         


Arg Ser Ser Asn Cys Ser Ala Gln Cys His Asn His Gly Val Cys Asn 
        595                 600                 605             


His Lys Gln Glu Cys His Cys His Ala Gly Trp Ala Pro Pro His Cys 
    610                 615                 620                 


Ala Lys Leu Leu Thr Glu Val His Ala Ala Ser Gly Ser Leu Pro 
625                 630                 635                 


<210>  22
<211>  296
<212>  PRT
<213>  Homo Sapiens

<400>  22

Ala Val Leu Pro Gln Thr Arg Tyr Val Glu Leu Phe Ile Val Val Asp 
1               5                   10                  15      


Lys Glu Arg Tyr Asp Met Met Gly Arg Asn Gln Thr Ala Val Arg Glu 
            20                  25                  30          


Glu Met Ile Leu Leu Ala Asn Tyr Leu Asp Ser Met Tyr Ile Met Leu 
        35                  40                  45              


Asn Ile Arg Ile Val Leu Val Gly Leu Glu Ile Trp Thr Asn Gly Asn 
    50                  55                  60                  


Leu Ile Asn Ile Val Gly Gly Ala Gly Asp Val Leu Gly Asn Phe Val 
65                  70                  75                  80  


Gln Trp Arg Glu Lys Phe Leu Ile Thr Arg Arg Arg His Asp Ser Ala 
                85                  90                  95      


Gln Leu Val Leu Lys Lys Gly Phe Gly Gly Thr Ala Gly Met Ala Phe 
            100                 105                 110         


Val Gly Thr Val Cys Ser Arg Ser His Ala Gly Gly Ile Asn Val Phe 
        115                 120                 125             


Gly Gln Ile Thr Val Glu Thr Phe Ala Ser Ile Val Ala His Glu Leu 
    130                 135                 140                 


Gly His Asn Leu Gly Met Asn His Asp Asp Gly Arg Asp Cys Ser Cys 
145                 150                 155                 160 


Gly Ala Lys Ser Cys Ile Met Asn Ser Gly Ala Ser Gly Ser Arg Asn 
                165                 170                 175     


Phe Ser Ser Cys Ser Ala Glu Asp Phe Glu Lys Leu Thr Leu Asn Lys 
            180                 185                 190         


Gly Gly Asn Cys Leu Leu Asn Ile Pro Lys Pro Asp Glu Ala Tyr Ser 
        195                 200                 205             


Ala Pro Ser Cys Gly Asn Lys Leu Val Asp Ala Gly Glu Glu Cys Asp 
    210                 215                 220                 


Cys Gly Thr Pro Lys Glu Cys Glu Leu Asp Pro Cys Cys Glu Gly Ser 
225                 230                 235                 240 


Thr Cys Lys Leu Lys Ser Phe Ala Glu Cys Ala Tyr Gly Asp Cys Cys 
                245                 250                 255     


Lys Asp Cys Arg Phe Leu Pro Gly Gly Thr Leu Cys Arg Gly Lys Thr 
            260                 265                 270         


Ser Glu Cys Asp Val Pro Glu Tyr Cys Asn Gly Ser Ser Gln Phe Cys 
        275                 280                 285             


Gln Pro Asp Val Phe Ile Gln Asn 
    290                 295     


<210>  23
<211>  1665
<212>  PRT
<213>  Homo Sapiens

<400>  23

Glu Lys Ser Pro Gly Ala Tyr Phe Leu Pro Glu Phe Ala Leu Ser Pro 
1               5                   10                  15      


Gln Gly Ser Phe Leu Glu Asp Thr Thr Gly Glu Gln Phe Leu Thr Tyr 
            20                  25                  30          


Arg Tyr Asp Asp Gln Thr Ser Arg Asn Thr Arg Ser Asp Glu Asp Lys 
        35                  40                  45              


Asp Gly Asn Trp Asp Ala Trp Gly Asp Trp Ser Asp Cys Ser Arg Thr 
    50                  55                  60                  


Cys Gly Gly Gly Ala Ser Tyr Ser Leu Arg Arg Cys Leu Thr Gly Arg 
65                  70                  75                  80  


Asn Cys Glu Gly Gln Asn Ile Arg Tyr Lys Thr Cys Ser Asn His Asp 
                85                  90                  95      


Cys Pro Pro Asp Ala Glu Asp Phe Arg Ala Gln Gln Cys Ser Ala Tyr 
            100                 105                 110         


Asn Asp Val Gln Tyr Gln Gly Arg Tyr Tyr Glu Trp Leu Pro Arg Tyr 
        115                 120                 125             


Asn Asp Pro Ala Ala Pro Cys Ala Leu Lys Cys His Ala Gln Gly Gln 
    130                 135                 140                 


Asn Leu Val Val Glu Leu Ala Pro Lys Val Leu Asp Gly Thr Arg Cys 
145                 150                 155                 160 


Asn Thr Asp Ser Leu Asp Met Cys Ile Ser Gly Ile Cys Gln Ala Val 
                165                 170                 175     


Gly Cys Asp Arg Gln Leu Gly Ser Asn Ala Lys Glu Asp Asn Cys Gly 
            180                 185                 190         


Val Cys Ala Gly Asp Gly Ser Thr Cys Arg Leu Val Arg Gly Gln Ser 
        195                 200                 205             


Lys Ser His Val Ser Pro Glu Lys Arg Glu Glu Asn Val Ile Ala Val 
    210                 215                 220                 


Pro Leu Gly Ser Arg Ser Val Arg Ile Thr Val Lys Gly Pro Ala His 
225                 230                 235                 240 


Leu Phe Ile Glu Ser Lys Thr Leu Gln Gly Ser Lys Gly Glu His Ser 
                245                 250                 255     


Phe Asn Ser Pro Gly Val Phe Val Val Glu Asn Thr Thr Val Glu Phe 
            260                 265                 270         


Gln Arg Gly Ser Glu Arg Gln Thr Phe Lys Ile Pro Gly Pro Leu Met 
        275                 280                 285             


Ala Asp Phe Ile Phe Lys Thr Arg Tyr Thr Ala Ala Lys Asp Ser Val 
    290                 295                 300                 


Val Gln Phe Phe Phe Tyr Gln Pro Ile Ser His Gln Trp Arg Gln Thr 
305                 310                 315                 320 


Asp Phe Phe Pro Cys Thr Val Thr Cys Gly Gly Gly Tyr Gln Leu Asn 
                325                 330                 335     


Ser Ala Glu Cys Val Asp Ile Arg Leu Lys Arg Val Val Pro Asp His 
            340                 345                 350         


Tyr Cys His Tyr Tyr Pro Glu Asn Val Lys Pro Lys Pro Lys Leu Lys 
        355                 360                 365             


Glu Cys Ser Met Asp Pro Cys Pro Ser Ser Asp Gly Phe Lys Glu Ile 
    370                 375                 380                 


Met Pro Tyr Asp His Phe Gln Pro Leu Pro Arg Trp Glu His Asn Pro 
385                 390                 395                 400 


Trp Thr Ala Cys Ser Val Ser Cys Gly Gly Gly Ile Gln Arg Arg Ser 
                405                 410                 415     


Phe Val Cys Val Glu Glu Ser Met His Gly Glu Ile Leu Gln Val Glu 
            420                 425                 430         


Glu Trp Lys Cys Met Tyr Ala Pro Lys Pro Lys Val Met Gln Thr Cys 
        435                 440                 445             


Asn Leu Phe Asp Cys Pro Lys Trp Ile Ala Met Glu Trp Ser Gln Cys 
    450                 455                 460                 


Thr Val Thr Cys Gly Arg Gly Leu Arg Tyr Arg Val Val Leu Cys Ile 
465                 470                 475                 480 


Asn His Arg Gly Glu His Val Gly Gly Cys Asn Pro Gln Leu Lys Leu 
                485                 490                 495     


His Ile Lys Glu Glu Cys Val Ile Pro Ile Pro Cys Tyr Lys Pro Lys 
            500                 505                 510         


Glu Lys Ser Pro Val Glu Ala Lys Leu Pro Trp Leu Lys Gln Ala Gln 
        515                 520                 525             


Glu Leu Glu Glu Thr Arg Ile Ala Thr Glu Glu Pro Thr Phe Ile Pro 
    530                 535                 540                 


Glu Pro Trp Ser Ala Cys Ser Thr Thr Cys Gly Pro Gly Val Gln Val 
545                 550                 555                 560 


Arg Glu Val Lys Cys Arg Val Leu Leu Thr Phe Thr Gln Thr Glu Thr 
                565                 570                 575     


Glu Leu Pro Glu Glu Glu Cys Glu Gly Pro Lys Leu Pro Thr Glu Arg 
            580                 585                 590         


Pro Cys Leu Leu Glu Ala Cys Asp Glu Ser Pro Ala Ser Arg Glu Leu 
        595                 600                 605             


Asp Ile Pro Leu Pro Glu Asp Ser Glu Thr Thr Tyr Asp Trp Glu Tyr 
    610                 615                 620                 


Ala Gly Phe Thr Pro Cys Thr Ala Thr Cys Leu Gly Gly His Gln Glu 
625                 630                 635                 640 


Ala Ile Ala Val Cys Leu His Ile Gln Thr Gln Gln Thr Val Asn Asp 
                645                 650                 655     


Ser Leu Cys Asp Met Val His Arg Pro Pro Ala Met Ser Gln Ala Cys 
            660                 665                 670         


Asn Thr Glu Pro Cys Pro Pro Arg Trp His Val Gly Ser Trp Gly Pro 
        675                 680                 685             


Cys Ser Ala Thr Cys Gly Val Gly Ile Gln Thr Arg Asp Val Tyr Cys 
    690                 695                 700                 


Leu His Pro Gly Glu Thr Pro Ala Pro Pro Glu Glu Cys Arg Asp Glu 
705                 710                 715                 720 


Lys Pro His Ala Leu Gln Ala Cys Asn Gln Phe Asp Cys Pro Pro Gly 
                725                 730                 735     


Trp His Ile Glu Glu Trp Gln Gln Cys Ser Arg Thr Cys Gly Gly Gly 
            740                 745                 750         


Thr Gln Asn Arg Arg Val Thr Cys Arg Gln Leu Leu Thr Asp Gly Ser 
        755                 760                 765             


Phe Leu Asn Leu Ser Asp Glu Leu Cys Gln Gly Pro Lys Ala Ser Ser 
    770                 775                 780                 


His Lys Ser Cys Ala Arg Thr Asp Cys Pro Pro His Leu Ala Val Gly 
785                 790                 795                 800 


Asp Trp Ser Lys Cys Ser Val Ser Cys Gly Val Gly Ile Gln Arg Arg 
                805                 810                 815     


Lys Gln Val Cys Gln Arg Leu Ala Ala Lys Gly Arg Arg Ile Pro Leu 
            820                 825                 830         


Ser Glu Met Met Cys Arg Asp Leu Pro Gly Leu Pro Leu Val Arg Ser 
        835                 840                 845             


Cys Gln Met Pro Glu Cys Ser Lys Ile Lys Ser Glu Met Lys Thr Lys 
    850                 855                 860                 


Leu Gly Glu Gln Gly Pro Gln Ile Leu Ser Val Gln Arg Val Tyr Ile 
865                 870                 875                 880 


Gln Thr Arg Glu Glu Lys Arg Ile Asn Leu Thr Ile Gly Ser Arg Ala 
                885                 890                 895     


Tyr Leu Leu Pro Asn Thr Ser Val Ile Ile Lys Cys Pro Val Arg Arg 
            900                 905                 910         


Phe Gln Lys Ser Leu Ile Gln Trp Glu Lys Asp Gly Arg Cys Leu Gln 
        915                 920                 925             


Asn Ser Lys Arg Leu Gly Ile Thr Lys Ser Gly Ser Leu Lys Ile His 
    930                 935                 940                 


Gly Leu Ala Ala Pro Asp Ile Gly Val Tyr Arg Cys Ile Ala Gly Phe 
945                 950                 955                 960 


Ala Gln Glu Thr Val Val Leu Lys Leu Ile Gly Thr Asp Asn Arg Leu 
                965                 970                 975     


Ile Ala Arg Pro Ala Leu Arg Glu Pro Met Arg Glu Tyr Pro Gly Met 
            980                 985                 990         


Asp His Ser Glu Ala Asn Ser Leu  Gly Val Thr Trp His  Lys Met Arg 
        995                 1000                 1005             


Gln Met  Trp Asn Asn Lys Asn  Asp Leu Tyr Leu Asp  Asp Asp His 
    1010                 1015                 1020             


Ile Ser  Asn Gln Pro Phe Leu  Arg Ala Leu Leu Gly  His Cys Ser 
    1025                 1030                 1035             


Asn Ser  Ala Gly Ser Thr Asn  Ser Trp Glu Leu Lys  Asn Lys Gln 
    1040                 1045                 1050             


Phe Glu  Ala Ala Val Lys Gln  Gly Ala Tyr Ser Met  Asp Thr Ala 
    1055                 1060                 1065             


Gln Phe  Asp Glu Leu Ile Arg  Asn Met Ser Gln Leu  Met Glu Thr 
    1070                 1075                 1080             


Gly Glu  Val Ser Asp Asp Leu  Ala Ser Gln Leu Ile  Tyr Gln Leu 
    1085                 1090                 1095             


Val Ala  Glu Leu Ala Lys Ala  Gln Pro Thr His Met  Gln Trp Arg 
    1100                 1105                 1110             


Gly Ile  Gln Glu Glu Thr Pro  Pro Ala Ala Gln Leu  Arg Gly Glu 
    1115                 1120                 1125             


Thr Gly  Ser Val Ser Gln Ser  Ser His Ala Lys Asn  Ser Gly Lys 
    1130                 1135                 1140             


Leu Thr  Phe Lys Pro Lys Gly  Pro Val Leu Met Arg  Gln Ser Gln 
    1145                 1150                 1155             


Pro Pro  Ser Ile Ser Phe Asn  Lys Thr Ile Asn Ser  Arg Ile Gly 
    1160                 1165                 1170             


Asn Thr  Val Tyr Ile Thr Lys  Arg Thr Glu Val Ile  Asn Ile Leu 
    1175                 1180                 1185             


Cys Asp  Leu Ile Thr Pro Ser  Glu Ala Thr Tyr Thr  Trp Thr Lys 
    1190                 1195                 1200             


Asp Gly  Thr Leu Leu Gln Pro  Ser Val Lys Ile Ile  Leu Asp Gly 
    1205                 1210                 1215             


Thr Gly  Lys Ile Gln Ile Gln  Asn Pro Thr Arg Lys  Glu Gln Gly 
    1220                 1225                 1230             


Ile Tyr  Glu Cys Ser Val Ala  Asn His Leu Gly Ser  Asp Val Glu 
    1235                 1240                 1245             


Ser Ser  Ser Val Leu Tyr Ala  Glu Ala Pro Val Ile  Leu Ser Val 
    1250                 1255                 1260             


Glu Arg  Asn Ile Thr Lys Pro  Glu His Asn His Leu  Ser Val Val 
    1265                 1270                 1275             


Val Gly  Gly Ile Val Glu Ala  Ala Leu Gly Ala Asn  Val Thr Ile 
    1280                 1285                 1290             


Arg Cys  Pro Val Lys Gly Val  Pro Gln Pro Asn Ile  Thr Trp Leu 
    1295                 1300                 1305             


Lys Arg  Gly Gly Ser Leu Ser  Gly Asn Val Ser Leu  Leu Phe Asn 
    1310                 1315                 1320             


Gly Ser  Leu Leu Leu Gln Asn  Val Ser Leu Glu Asn  Glu Gly Thr 
    1325                 1330                 1335             


Tyr Val  Cys Ile Ala Thr Asn  Ala Leu Gly Lys Ala  Val Ala Thr 
    1340                 1345                 1350             


Ser Val  Leu His Leu Leu Glu  Arg Arg Trp Pro Glu  Ser Arg Ile 
    1355                 1360                 1365             


Val Phe  Leu Gln Gly His Lys  Lys Tyr Ile Leu Gln  Ala Thr Asn 
    1370                 1375                 1380             


Thr Arg  Thr Asn Ser Asn Asp  Pro Thr Gly Glu Pro  Pro Pro Gln 
    1385                 1390                 1395             


Glu Pro  Phe Trp Glu Pro Gly  Asn Trp Ser His Cys  Ser Ala Thr 
    1400                 1405                 1410             


Cys Gly  His Leu Gly Ala Arg  Ile Gln Arg Pro Gln  Cys Val Met 
    1415                 1420                 1425             


Ala Asn  Gly Gln Glu Val Ser  Glu Ala Leu Cys Asp  His Leu Gln 
    1430                 1435                 1440             


Lys Pro  Leu Ala Gly Phe Glu  Pro Cys Asn Ile Arg  Asp Cys Pro 
    1445                 1450                 1455             


Ala Arg  Trp Phe Thr Ser Val  Trp Ser Gln Cys Ser  Val Ser Cys 
    1460                 1465                 1470             


Gly Glu  Gly Tyr His Ser Arg  Gln Val Thr Cys Lys  Arg Thr Lys 
    1475                 1480                 1485             


Ala Asn  Gly Thr Val Gln Val  Val Ser Pro Arg Ser  Cys Ala Pro 
    1490                 1495                 1500             


Lys Asp  Arg Pro Leu Gly Arg  Lys Pro Cys Phe Gly  His Pro Cys 
    1505                 1510                 1515             


Val Gln  Trp Glu Pro Gly Asn  Arg Cys Pro Gly Arg  Cys Met Gly 
    1520                 1525                 1530             


Arg Ala  Val Arg Met Gln Gln  Arg His Thr Ala Cys  Gln His Asn 
    1535                 1540                 1545             


Ser Ser  Asp Ser Asn Cys Asp  Asp Arg Lys Arg Pro  Thr Leu Arg 
    1550                 1555                 1560             


Arg Asn  Cys Thr Ser Gly Ala  Cys Asp Val Cys Trp  His Thr Gly 
    1565                 1570                 1575             


Pro Trp  Lys Pro Cys Thr Ala  Ala Cys Gly Arg Gly  Phe Gln Ser 
    1580                 1585                 1590             


Arg Lys  Val Asp Cys Ile His  Thr Arg Ser Cys Lys  Pro Val Ala 
    1595                 1600                 1605             


Lys Arg  His Cys Val Gln Lys  Lys Lys Pro Ile Ser  Trp Arg His 
    1610                 1615                 1620             


Cys Leu  Gly Pro Ser Cys Asp  Arg Asp Cys Thr Asp  Thr Thr His 
    1625                 1630                 1635             


Tyr Cys  Met Phe Val Lys His  Leu Asn Leu Cys Ser  Leu Asp Arg 
    1640                 1645                 1650             


Tyr Lys  Gln Arg Cys Cys Gln  Ser Cys Gln Glu Gly  
    1655                 1660                 1665 


<210>  24
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  24

Gln Asp Ser Arg Gly Cys Ala Arg Trp Cys Pro Gln Asp Ser Ser Cys 
1               5                   10                  15      


Val Asn Ala Thr Ala Cys Arg Cys Asn Pro Gly Phe Ser Ser Phe Ser 
            20                  25                  30          


Glu Ile Ile Thr Thr Pro Met Glu Thr Cys Asp Asp Ile Asn Glu Cys 
        35                  40                  45              


Ala Thr Leu Ser Lys Val Ser Cys Gly Lys Phe Ser Asp Cys Trp Asn 
    50                  55                  60                  


Thr Glu Gly Ser Tyr Asp Cys Val Cys Ser Pro Gly Tyr Glu Pro Val 
65                  70                  75                  80  


Ser Gly Ala Lys Thr Phe Lys Asn Glu Ser Glu Asn Thr Cys Gln Asp 
                85                  90                  95      


Val Asp Glu Cys Gln Gln Asn Pro Arg Leu Cys Lys Ser Tyr Gly Thr 
            100                 105                 110         


Cys Val Asn Thr Leu Gly Ser Tyr Thr Cys Gln Cys Leu Pro Gly Phe 
        115                 120                 125             


Lys Phe Ile Pro Glu Asp Pro Lys Val Cys Thr Asp Val Asn Glu Cys 
    130                 135                 140                 


Thr Ser Gly Gln Asn Pro Cys His Ser Ser Thr His Cys Leu Asn Asn 
145                 150                 155                 160 


Val Gly Ser Tyr Gln Cys Arg Cys Arg Pro Gly Trp Gln Pro Ile Pro 
                165                 170                 175     


Gly Ser Pro Asn Gly Pro Asn Asn Thr Val Cys Glu Asp Val Asp Glu 
            180                 185                 190         


Cys Ser Ser Gly Gln His Gln Cys Asp Ser Ser Thr Val Cys Phe Asn 
        195                 200                 205             


Thr Val Gly Ser Tyr Ser Cys Arg Cys Arg Pro Gly Trp Lys Pro Arg 
    210                 215                 220                 


His Gly Ile Pro Asn Asn Gln Lys Asp Thr Val Cys Glu Asp Met Thr 
225                 230                 235                 240 


Phe Ser Thr Trp Thr Pro Pro Pro Gly Val His Ser Gln Thr Leu Ser 
                245                 250                 255     


Arg Phe Phe Asp Lys Val Gln Asp Leu Gly Arg Asp Tyr Lys Pro Gly 
            260                 265                 270         


Leu Ala Asn Asn Thr Ile Gln Ser Ile Leu Gln Ala Leu Asp Glu Leu 
        275                 280                 285             


Leu Glu Val Pro Gly Asp Leu Glu Thr Leu Pro Arg Leu Gln Gln His 
    290                 295                 300                 


Cys Val Ala Ser His Leu Leu Asp Gly Leu Glu Asp Val Leu Arg Gly 
305                 310                 315                 320 


Leu Ser Lys Asn Leu Ser Asn Gly Leu Leu Asn Phe Ser Tyr Pro Ala 
                325                 330                 335     


Gly Thr Glu Leu Ser Leu Glu Val Gln Lys Gln Val Asp Arg Ser Val 
            340                 345                 350         


Thr Leu Arg Gln Asn Gln Ala Val Met Gln Leu Asp Trp Asn Gln Ala 
        355                 360                 365             


Gln Lys Ser Gly Asp Pro Gly Pro Ser Val Val Gly Leu Val Ser Ile 
    370                 375                 380                 


Pro Gly Met Gly Lys Leu Leu Ala Glu Ala Pro Leu Val Leu Glu Pro 
385                 390                 395                 400 


Glu Lys Gln Met Leu Leu His Glu Thr His Gln Gly Leu Leu Gln Asp 
                405                 410                 415     


Gly Ser Pro Ile Leu Leu Ser Asp Val Ile Ser Ala Phe Leu Ser Asn 
            420                 425                 430         


Asn Asp Thr Gln Asn Leu Ser Ser Pro Val Thr Phe Thr Phe Ser His 
        435                 440                 445             


Arg Ser Val Ile Pro Arg Gln Lys Val Leu Cys Val Phe Trp Glu His 
    450                 455                 460                 


Gly Gln Asn Gly Cys Gly His Trp Ala Thr Thr Gly Cys Ser Thr Ile 
465                 470                 475                 480 


Gly Thr Arg Asp Thr Ser Thr Ile Cys Arg Cys Thr His Leu Ser Ser 
                485                 490                 495     


Phe Ala Val Leu Met Ala His Tyr Asp Val Gln Glu Glu Asp Pro Val 
            500                 505                 510         


Leu Thr Val Ile Thr 
        515         


<210>  25
<211>  291
<212>  PRT
<213>  Homo Sapiens

<400>  25

Asp Ile Asn Glu Cys Thr Pro Pro Tyr Ser Val Tyr Cys Gly Phe Asn 
1               5                   10                  15      


Ala Val Cys Tyr Asn Val Glu Gly Ser Phe Tyr Cys Gln Cys Val Pro 
            20                  25                  30          


Gly Tyr Arg Leu His Ser Gly Asn Glu Gln Phe Ser Asn Ser Asn Glu 
        35                  40                  45              


Asn Thr Cys Gln Asp Thr Thr Ser Ser Lys Thr Thr Gln Gly Arg Lys 
    50                  55                  60                  


Glu Leu Gln Lys Ile Val Asp Lys Phe Glu Ser Leu Leu Thr Asn Gln 
65                  70                  75                  80  


Thr Leu Trp Arg Thr Glu Gly Arg Gln Glu Ile Ser Ser Thr Ala Thr 
                85                  90                  95      


Thr Ile Leu Arg Asp Val Glu Ser Lys Val Leu Glu Thr Ala Leu Lys 
            100                 105                 110         


Asp Pro Glu Gln Lys Val Leu Lys Ile Gln Asn Asp Ser Val Ala Ile 
        115                 120                 125             


Glu Thr Gln Ala Ile Thr Asp Asn Cys Ser Glu Glu Arg Lys Thr Phe 
    130                 135                 140                 


Asn Leu Asn Val Gln Met Asn Ser Met Asp Ile Arg Cys Ser Asp Ile 
145                 150                 155                 160 


Ile Gln Gly Asp Thr Gln Gly Pro Ser Ala Ile Ala Phe Ile Ser Tyr 
                165                 170                 175     


Ser Ser Leu Gly Asn Ile Ile Asn Ala Thr Phe Phe Glu Glu Met Asp 
            180                 185                 190         


Lys Lys Asp Gln Val Tyr Leu Asn Ser Gln Val Val Ser Ala Ala Ile 
        195                 200                 205             


Gly Pro Lys Arg Asn Val Ser Leu Ser Lys Ser Val Thr Leu Thr Phe 
    210                 215                 220                 


Gln His Val Lys Met Thr Pro Ser Thr Lys Lys Val Phe Cys Val Tyr 
225                 230                 235                 240 


Trp Lys Ser Thr Gly Gln Gly Ser Gln Trp Ser Arg Asp Gly Cys Phe 
                245                 250                 255     


Leu Ile His Val Asn Lys Ser His Thr Met Cys Asn Cys Ser His Leu 
            260                 265                 270         


Ser Ser Phe Ala Val Leu Met Ala Leu Thr Ser Gln Glu Glu Asp Pro 
        275                 280                 285             


Val Leu Thr 
    290     


<210>  26
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  26

Pro Pro Cys Pro Lys Tyr Ala Ser Cys His Asn Ser Thr His Cys Thr 
1               5                   10                  15      


Cys Glu Asp Gly Phe Arg Ala Arg Ser Gly Arg Thr Tyr Phe His Asp 
            20                  25                  30          


Ser Ser Glu Lys Cys Glu Asp Ile Asn Glu Cys Glu Thr Gly Leu Ala 
        35                  40                  45              


Lys Cys Lys Tyr Lys Ala Tyr Cys Arg Asn Lys Val Gly Gly Tyr Ile 
    50                  55                  60                  


Cys Ser Cys Leu Val Lys Tyr Thr Leu Phe Asn Phe Leu Ala Gly Ile 
65                  70                  75                  80  


Ile Asp Tyr Asp His Pro Asp Cys Tyr Glu Asn Asn Ser Gln Gly Thr 
                85                  90                  95      


Thr Gln Ser Asn Val Asp Ile Trp Val Ser Gly Val Lys Pro Gly Phe 
            100                 105                 110         


Gly Lys Gln Leu Pro Gly Asp Lys Arg Thr Lys His Ile Cys Val Tyr 
        115                 120                 125             


Trp Glu Gly Ser Glu Gly Gly Trp Ser Thr Glu Gly Cys Ser His Val 
    130                 135                 140                 


His Ser Asn Gly Ser Tyr Thr Lys Cys Lys Cys Phe His Leu Ser Ser 
145                 150                 155                 160 


Phe Ala Val Leu Val Ala Leu Ala Pro Lys Glu Asp Pro Val Leu Thr 
                165                 170                 175     


<210>  27
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  27

Asp Val Asp Glu Cys Ser Ser Gly Gln His Gln Cys Asp Ser Ser Thr 
1               5                   10                  15      


Val Cys Phe Asn Thr Val Gly Ser Tyr Ser Cys Arg Cys Arg Pro Gly 
            20                  25                  30          


Trp Lys Pro Arg His Gly Ile Pro Asn Asn Gln Lys Asp Thr Val Cys 
        35                  40                  45              


Glu Asp Met Thr Phe Ser Thr Trp Thr Pro Pro Pro Gly Val His Ser 
    50                  55                  60                  


Gln Thr Leu Ser Arg Phe Phe Asp Lys Val Gln Asp Leu Gly Arg Asp 
65                  70                  75                  80  


Ser Lys Thr Ser Ser Ala Glu Val Thr Ile Gln Asn Val Ile Lys Leu 
                85                  90                  95      


Val Asp Glu Leu Met Glu Ala Pro Gly Asp Val Glu Ala Leu Ala Pro 
            100                 105                 110         


Pro Val Arg His Leu Ile Ala Thr Gln Leu Leu Ser Asn Leu Glu Asp 
        115                 120                 125             


Ile Met Arg Ile Leu Ala Lys Ser Leu Pro Lys Gly Pro Phe Thr Tyr 
    130                 135                 140                 


Ile Ser Pro Ser Asn Thr Glu Leu Thr Leu Met Ile Gln Glu Arg Gly 
145                 150                 155                 160 


Asp Lys Asn Val Thr Met Gly Gln Ser Ser Ala Arg Met Lys Leu Asn 
                165                 170                 175     


Trp Ala Val Ala Ala Gly Ala Glu Asp Pro Gly Pro Ala Val Ala Gly 
            180                 185                 190         


Ile Leu Ser Ile Gln Asn Met Thr Thr Leu Leu Ala Asn Ala Ser Leu 
        195                 200                 205             


Asn Leu His Ser Lys Lys Gln Ala Glu Leu Glu Glu Ile Tyr Glu Ser 
    210                 215                 220                 


Ser Ile Arg Gly Val Gln Leu Arg Arg Leu Ser Ala Val Asn Ser Ile 
225                 230                 235                 240 


Phe Leu Ser His Asn Asn Thr Lys Glu Leu Asn Ser Pro Ile Leu Phe 
                245                 250                 255     


Ala Phe Ser His Leu Glu Ser Ser Asp Gly Glu Ala Gly Arg Asp Pro 
            260                 265                 270         


Pro Ala Lys Asp Val Met Pro Gly Pro Arg Gln Glu Leu Leu Cys Ala 
        275                 280                 285             


Phe Trp Lys Ser Asp Ser Asp Arg Gly Gly His Trp Ala Thr Glu Gly 
    290                 295                 300                 


Cys Gln Val Leu Gly Ser Lys Asn Gly Ser Thr Thr Cys Gln Cys Ser 
305                 310                 315                 320 


His Leu 
        


<210>  28
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  28

Tyr Arg Gln Ser Met Asn Asn Phe Gln Gly Leu Arg Ser Phe Gly Cys 
1               5                   10                  15      


Arg Phe Gly Thr Cys Thr Val Gln Lys Leu Ala His Gln Ile Tyr Gln 
            20                  25                  30          


Phe Thr Asp Lys Asp Lys Asp Asn Val Ala Pro Arg Ser Lys Ile Ser 
        35                  40                  45              


Pro Gln Gly Tyr 
    50          


<210>  29
<211>  47
<212>  PRT
<213>  Homo Sapiens

<400>  29

Thr Gln Ala Gln Leu Leu Arg Val Gly Cys Val Leu Gly Thr Cys Gln 
1               5                   10                  15      


Val Gln Asn Leu Ser His Arg Leu Trp Gln Leu Met Gly Pro Ala Gly 
            20                  25                  30          


Arg Gln Asp Ser Ala Pro Val Asp Pro Ser Ser Pro His Ser Tyr 
        35                  40                  45          


<210>  30
<211>  320
<212>  PRT
<213>  Homo Sapiens

<400>  30

Ala Gln Asn Ile Thr Ala Arg Ile Gly Glu Pro Leu Val Leu Lys Cys 
1               5                   10                  15      


Lys Gly Ala Pro Lys Lys Pro Pro Gln Arg Leu Glu Trp Lys Leu Asn 
            20                  25                  30          


Thr Gly Arg Thr Glu Ala Trp Lys Val Leu Ser Pro Gln Gly Gly Gly 
        35                  40                  45              


Pro Trp Asp Ser Val Ala Arg Val Leu Pro Asn Gly Ser Leu Phe Leu 
    50                  55                  60                  


Pro Ala Val Gly Ile Gln Asp Glu Gly Ile Phe Arg Cys Gln Ala Met 
65                  70                  75                  80  


Asn Arg Asn Gly Lys Glu Thr Lys Ser Asn Tyr Arg Val Arg Val Tyr 
                85                  90                  95      


Gln Ile Pro Gly Lys Pro Glu Ile Val Asp Ser Ala Ser Glu Leu Thr 
            100                 105                 110         


Ala Gly Val Pro Asn Lys Val Gly Thr Cys Val Ser Glu Gly Ser Tyr 
        115                 120                 125             


Pro Ala Gly Thr Leu Ser Trp His Leu Asp Gly Lys Pro Leu Val Pro 
    130                 135                 140                 


Asn Glu Lys Gly Val Ser Val Lys Glu Gln Thr Arg Arg His Pro Glu 
145                 150                 155                 160 


Thr Gly Leu Phe Thr Leu Gln Ser Glu Leu Met Val Thr Pro Ala Arg 
                165                 170                 175     


Gly Gly Asp Pro Arg Pro Thr Phe Ser Cys Ser Phe Ser Pro Gly Leu 
            180                 185                 190         


Pro Arg His Arg Ala Leu Arg Thr Ala Pro Ile Gln Pro Arg Val Trp 
        195                 200                 205             


Glu Pro Val Pro Leu Glu Glu Val Gln Leu Val Val Glu Pro Glu Gly 
    210                 215                 220                 


Gly Ala Val Ala Pro Gly Gly Thr Val Thr Leu Thr Cys Glu Val Pro 
225                 230                 235                 240 


Ala Gln Pro Ser Pro Gln Ile His Trp Met Lys Asp Gly Val Pro Leu 
                245                 250                 255     


Pro Leu Pro Pro Ser Pro Val Leu Ile Leu Pro Glu Ile Gly Pro Gln 
            260                 265                 270         


Asp Gln Gly Thr Tyr Ser Cys Val Ala Thr His Ser Ser His Gly Pro 
        275                 280                 285             


Gln Glu Ser Arg Ala Val Ser Ile Ser Ile Ile Glu Pro Gly Glu Glu 
    290                 295                 300                 


Gly Pro Thr Ala Gly Ser Val Gly Gly Ser Gly Leu Gly Thr Leu Ala 
305                 310                 315                 320 


<210>  31
<211>  432
<212>  PRT
<213>  Homo Sapiens

<400>  31

Cys Arg Phe Gly Ala Leu Cys Glu Ala Glu Thr Gly Arg Cys Val Cys 
1               5                   10                  15      


Pro Ser Glu Cys Val Ala Leu Ala Gln Pro Val Cys Gly Ser Asp Gly 
            20                  25                  30          


His Thr Tyr Pro Ser Glu Cys Met Leu His Val His Ala Cys Thr His 
        35                  40                  45              


Gln Ile Ser Leu His Val Ala Ser Ala Gly Pro Cys Glu Thr Cys Gly 
    50                  55                  60                  


Asp Ala Val Cys Ala Phe Gly Ala Val Cys Ser Ala Gly Gln Cys Val 
65                  70                  75                  80  


Cys Pro Arg Cys Glu His Pro Pro Pro Gly Pro Val Cys Gly Ser Asp 
                85                  90                  95      


Gly Val Thr Tyr Gly Ser Ala Cys Glu Leu Arg Glu Ala Ala Cys Leu 
            100                 105                 110         


Gln Gln Thr Gln Ile Glu Glu Ala Arg Ala Gly Pro Cys Glu Gln Ala 
        115                 120                 125             


Glu Cys Gly Ser Gly Gly Ser Gly Ser Gly Glu Asp Gly Asp Cys Glu 
    130                 135                 140                 


Gln Glu Leu Cys Arg Gln Arg Gly Gly Ile Trp Asp Glu Asp Ser Glu 
145                 150                 155                 160 


Asp Gly Pro Cys Val Cys Asp Phe Ser Cys Gln Ser Val Pro Gly Ser 
                165                 170                 175     


Pro Val Cys Gly Ser Asp Gly Val Thr Tyr Ser Thr Glu Cys Glu Leu 
            180                 185                 190         


Lys Lys Ala Arg Cys Glu Ser Gln Arg Gly Leu Tyr Val Ala Ala Gln 
        195                 200                 205             


Gly Ala Cys Arg Gly Pro Thr Phe Ala Pro Leu Pro Pro Val Ala Pro 
    210                 215                 220                 


Leu His Cys Ala Gln Thr Pro Tyr Gly Cys Cys Gln Asp Asn Ile Thr 
225                 230                 235                 240 


Ala Ala Arg Gly Val Gly Leu Ala Gly Cys Pro Ser Ala Cys Gln Cys 
                245                 250                 255     


Asn Pro His Gly Ser Tyr Gly Gly Thr Cys Asp Pro Ala Thr Gly Gln 
            260                 265                 270         


Cys Ser Cys Arg Pro Gly Val Gly Gly Leu Arg Cys Asp Arg Cys Glu 
        275                 280                 285             


Pro Gly Phe Trp Asn Phe Arg Gly Ile Val Thr Asp Gly Arg Ser Gly 
    290                 295                 300                 


Cys Thr Pro Cys Ser Cys Asp Pro Gln Gly Ala Val Arg Asp Asp Cys 
305                 310                 315                 320 


Glu Gln Met Thr Gly Leu Cys Ser Cys Lys Pro Gly Val Ala Gly Pro 
                325                 330                 335     


Lys Cys Gly Gln Cys Pro Asp Gly Arg Ala Leu Gly Pro Ala Gly Cys 
            340                 345                 350         


Glu Ala Asp Ala Ser Ala Pro Ala Thr Cys Ala Glu Met Arg Cys Glu 
        355                 360                 365             


Phe Gly Ala Arg Cys Val Glu Glu Ser Gly Ser Ala His Cys Val Cys 
    370                 375                 380                 


Pro Met Leu Thr Cys Pro Glu Ala Asn Ala Thr Lys Val Cys Gly Ser 
385                 390                 395                 400 


Asp Gly Val Thr Tyr Gly Asn Glu Cys Gln Leu Lys Thr Ile Ala Cys 
                405                 410                 415     


Arg Gln Gly Leu Gln Ile Ser Ile Gln Ser Leu Gly Pro Cys Gln Glu 
            420                 425                 430         


<210>  32
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  32

Trp Tyr Thr Val Asn Ser Ala Tyr Gly Asp Thr Ile Ile Ile Pro Cys 
1               5                   10                  15      


Arg Leu Asp Val Pro Gln Asn Leu Met Phe Gly Lys Trp Lys Tyr Glu 
            20                  25                  30          


Lys Pro Asp Gly Ser Pro Val Phe Ile Ala Phe Arg Ser Ser Thr Lys 
        35                  40                  45              


Lys Ser Val Gln Tyr Asp Asp Val Pro Glu Tyr Lys Asp Arg Leu Asn 
    50                  55                  60                  


Leu Ser Glu Asn Tyr Thr Leu Ser Ile Ser Asn Ala Arg Ile Ser Asp 
65                  70                  75                  80  


Glu Lys Arg Phe Val Cys Met Leu Val Thr Glu Asp Asn Val Phe Glu 
                85                  90                  95      


Ala Pro Thr Ile Val Lys Val Phe Lys Gln Pro Ser Lys Pro Glu Ile 
            100                 105                 110         


Val Ser Lys Ala Leu Phe Leu Glu Thr Glu Gln Leu Lys Lys Leu Gly 
        115                 120                 125             


Asp Cys Ile Ser Glu Asp Ser Tyr Pro Asp Gly Asn Ile Thr Trp Tyr 
    130                 135                 140                 


Arg Asn Gly Lys Val Leu His Pro Leu Glu Gly Ala Val Val Ile Ile 
145                 150                 155                 160 


Phe Lys Lys Glu Met Asp Pro Val Thr Gln Leu Tyr Thr Met Thr Ser 
                165                 170                 175     


Thr Leu Glu Tyr Lys Thr Thr Lys Ala Asp Ile Gln Met Pro Phe Thr 
            180                 185                 190         


Cys Ser Val Thr Tyr Tyr Gly Pro Ser Gly Gln Lys Thr Ile His Ser 
        195                 200                 205             


Glu Gln Ala Val Phe Asp Ile Tyr Tyr Pro Thr Glu Gln Val Thr Ile 
    210                 215                 220                 


Gln Val Leu Pro Pro Lys Asn Ala Ile Lys Glu Gly Asp Asn Ile Thr 
225                 230                 235                 240 


Leu Lys Cys Leu Gly Asn Gly Asn Pro Pro Pro Glu Glu Phe Leu Phe 
                245                 250                 255     


Tyr Leu Pro Gly Gln Pro Glu Gly Ile Arg Ser Ser Asn Thr Tyr Thr 
            260                 265                 270         


Leu Thr Asp Val Arg Arg Asn Ala Thr Gly Asp Tyr Lys Cys Ser Leu 
        275                 280                 285             


Ile Asp Lys Lys Ser Met Ile Ala Ser Thr Ala Ile Thr Val His Tyr 
    290                 295                 300                 


Leu Asp Leu Ser Leu Asn Pro Ser Gly Glu Val Thr Arg Gln Ile Gly 
305                 310                 315                 320 


Asp Ala Leu Pro Val Ser Cys Thr Ile Ser Ala Ser Arg Asn Ala Thr 
                325                 330                 335     


Val Val Trp Met Lys Asp Asn Ile Arg Leu Arg Ser Ser Pro Ser Phe 
            340                 345                 350         


Ser Ser Leu His Tyr Gln Asp Ala Gly Asn Tyr Val Cys Glu Thr Ala 
        355                 360                 365             


Leu Gln Glu Val Glu Gly Leu Lys Lys Arg Glu Ser Leu Thr Leu Ile 
    370                 375                 380                 


Val Glu Gly Lys Pro Gln Ile Lys Met Thr Lys Lys Thr Asp Pro Ser 
385                 390                 395                 400 


Gly Leu Ser Lys Thr Ile Ile Cys His Val Glu Gly Phe Pro Lys Pro 
                405                 410                 415     


Ala Ile Gln Trp Thr Ile Thr Gly Ser Gly Ser Val Ile Asn Gln Thr 
            420                 425                 430         


Glu Glu Ser Pro Tyr Ile Asn Gly Arg Tyr Tyr Ser Lys Ile Ile Ile 
        435                 440                 445             


Ser Pro Glu Glu Asn Val Thr Leu Thr Cys Thr Ala Glu Asn Gln Leu 
    450                 455                 460                 


Glu Arg Thr Val Asn Ser Leu Asn Val Ser Ala Ile Ser Ile Pro Glu 
465                 470                 475                 480 


His Asp Glu Ala Asp Glu Ile Ser Asp Glu Asn Arg Glu Lys Val Asn 
                485                 490                 495     


Asp Gln Ala Lys 
            500 


<210>  33
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  33

Leu Asn Asp Leu Asn Val Ser Pro Pro Glu Leu Thr Val His Val Gly 
1               5                   10                  15      


Asp Ser Ala Leu Met Gly Cys Val Phe Gln Ser Thr Glu Asp Lys Cys 
            20                  25                  30          


Ile Phe Lys Ile Asp Trp Thr Leu Ser Pro Gly Glu His Ala Lys Asp 
        35                  40                  45              


Glu Tyr Val Leu Tyr Tyr Tyr Ser Asn Leu Ser Val Pro Ile Gly Arg 
    50                  55                  60                  


Phe Gln Asn Arg Val His Leu Met Gly Asp Ile Leu Cys Asn Asp Gly 
65                  70                  75                  80  


Ser Leu Leu Leu Gln Asp Val Gln Glu Ala Asp Gln Gly Thr Tyr Ile 
                85                  90                  95      


Cys Glu Ile Arg Leu Lys Gly Glu Ser Gln Val Phe Lys Lys Ala Val 
            100                 105                 110         


Val Leu His Val Leu Pro Glu Glu Pro Lys Glu Leu Met Val His Val 
        115                 120                 125             


Gly Gly Leu Ile Gln Met Gly Cys Val Phe Gln Ser Thr Glu Val Lys 
    130                 135                 140                 


His Val Thr Lys Val Glu Trp Ile Phe Ser Gly Arg Arg Ala Lys Glu 
145                 150                 155                 160 


Glu Ile Val Phe Arg Tyr Tyr His Lys Leu Arg Met Ser Val Glu Tyr 
                165                 170                 175     


Ser Gln Ser Trp Gly His Phe Gln Asn Arg Val Asn Leu Val Gly Asp 
            180                 185                 190         


Ile Phe Arg Asn Asp Gly Ser Ile Met Leu Gln Gly Val Arg Glu Ser 
        195                 200                 205             


Asp Gly Gly Asn Tyr Thr Cys Ser Ile His Leu Gly Asn Leu Val Phe 
    210                 215                 220                 


Lys Lys Thr Ile Val Leu His Val Ser Pro Glu Glu Pro Arg Thr Leu 
225                 230                 235                 240 


Val Thr Pro Ala Ala Leu Arg Pro Leu Val Leu Gly Gly Asn Gln Leu 
                245                 250                 255     


<210>  34
<211>  345
<212>  PRT
<213>  Homo Sapiens

<400>  34

Gly Arg Ala Val Val Ser Cys Pro Ala Ala Cys Leu Cys Ala Ser Asn 
1               5                   10                  15      


Ile Leu Ser Cys Ser Lys Gln Gln Leu Pro Asn Val Pro His Ser Leu 
            20                  25                  30          


Pro Ser Tyr Thr Ala Leu Leu Asp Leu Ser His Asn Asn Leu Ser Arg 
        35                  40                  45              


Leu Arg Ala Glu Trp Thr Pro Thr Arg Leu Thr Gln Leu His Ser Leu 
    50                  55                  60                  


Leu Leu Ser His Asn His Leu Asn Phe Ile Ser Ser Glu Ala Phe Ser 
65                  70                  75                  80  


Pro Val Pro Asn Leu Arg Tyr Leu Asp Leu Ser Ser Asn Gln Leu Arg 
                85                  90                  95      


Thr Leu Asp Glu Phe Leu Phe Ser Asp Leu Gln Val Leu Glu Val Leu 
            100                 105                 110         


Leu Leu Tyr Asn Asn His Ile Met Ala Val Asp Arg Cys Ala Phe Asp 
        115                 120                 125             


Asp Met Ala Gln Leu Gln Lys Leu Tyr Leu Ser Gln Asn Gln Ile Ser 
    130                 135                 140                 


Arg Phe Pro Leu Glu Leu Val Lys Glu Gly Ala Lys Leu Pro Lys Leu 
145                 150                 155                 160 


Thr Leu Leu Asp Leu Ser Ser Asn Lys Leu Lys Asn Leu Pro Leu Pro 
                165                 170                 175     


Asp Leu Gln Lys Leu Pro Ala Trp Ile Lys Asn Gly Leu Tyr Leu His 
            180                 185                 190         


Asn Asn Pro Leu Asn Cys Asp Cys Glu Leu Tyr Gln Leu Phe Ser His 
        195                 200                 205             


Trp Gln Tyr Arg Gln Leu Ser Ser Val Met Asp Phe Gln Glu Asp Leu 
    210                 215                 220                 


Tyr Cys Met Asn Ser Lys Lys Leu His Asn Val Phe Asn Leu Ser Phe 
225                 230                 235                 240 


Leu Asn Cys Gly Glu Tyr Lys Glu Arg Ala Trp Glu Ala His Leu Gly 
                245                 250                 255     


Asp Thr Leu Ile Ile Lys Cys Asp Thr Lys Gln Gln Gly Met Thr Lys 
            260                 265                 270         


Val Trp Val Thr Pro Ser Asn Glu Arg Val Leu Asp Glu Val Thr Asn 
        275                 280                 285             


Gly Thr Val Ser Val Ser Lys Asp Gly Ser Leu Leu Phe Gln Gln Val 
    290                 295                 300                 


Gln Val Glu Asp Gly Gly Val Tyr Thr Cys Tyr Ala Met Gly Glu Thr 
305                 310                 315                 320 


Phe Asn Glu Thr Leu Ser Val Glu Leu Lys Val His Asn Phe Thr Leu 
                325                 330                 335     


His Gly His His Asp Thr Leu Asn Thr 
            340                 345 


<210>  35
<211>  359
<212>  PRT
<213>  Homo Sapiens

<400>  35

Val Cys Pro Thr Ala Cys Ile Cys Ala Thr Asp Ile Val Ser Cys Thr 
1               5                   10                  15      


Asn Lys Asn Leu Ser Lys Val Pro Gly Asn Leu Phe Arg Leu Ile Lys 
            20                  25                  30          


Arg Leu Asp Leu Ser Tyr Asn Arg Ile Gly Leu Leu Asp Ser Glu Trp 
        35                  40                  45              


Ile Pro Val Ser Phe Ala Lys Leu Asn Thr Leu Ile Leu Arg His Asn 
    50                  55                  60                  


Asn Ile Thr Ser Ile Ser Thr Gly Ser Phe Ser Thr Thr Pro Asn Leu 
65                  70                  75                  80  


Lys Cys Leu Asp Leu Ser Ser Asn Lys Leu Lys Thr Val Lys Asn Ala 
                85                  90                  95      


Val Phe Gln Glu Leu Lys Val Leu Glu Val Leu Leu Leu Tyr Asn Asn 
            100                 105                 110         


His Ile Ser Tyr Leu Asp Pro Ser Ala Phe Gly Gly Leu Ser Gln Leu 
        115                 120                 125             


Gln Lys Leu Tyr Leu Ser Gly Asn Phe Leu Thr Gln Phe Pro Met Asp 
    130                 135                 140                 


Leu Tyr Val Gly Arg Phe Lys Leu Ala Glu Leu Met Phe Leu Asp Val 
145                 150                 155                 160 


Ser Tyr Asn Arg Ile Pro Ser Met Pro Met His His Ile Asn Leu Val 
                165                 170                 175     


Pro Gly Lys Gln Leu Arg Gly Ile Tyr Leu His Gly Asn Pro Phe Val 
            180                 185                 190         


Cys Asp Cys Ser Leu Tyr Ser Leu Leu Val Phe Trp Tyr Arg Arg His 
        195                 200                 205             


Phe Ser Ser Val Met Asp Phe Lys Asn Asp Tyr Thr Cys Arg Leu Trp 
    210                 215                 220                 


Ser Asp Ser Arg His Ser Arg Gln Val Leu Leu Leu Gln Asp Ser Phe 
225                 230                 235                 240 


Met Asn Cys Ser Asp Ser Ile Ile Asn Gly Ser Phe Arg Ala Leu Gly 
                245                 250                 255     


Phe Ile His Glu Ala Gln Val Gly Glu Arg Leu Met Val His Cys Asp 
            260                 265                 270         


Ser Lys Thr Gly Asn Ala Asn Thr Asp Phe Ile Trp Val Gly Pro Asp 
        275                 280                 285             


Asn Arg Leu Leu Glu Pro Asp Lys Glu Met Glu Asn Phe Tyr Val Phe 
    290                 295                 300                 


His Asn Gly Ser Leu Val Ile Glu Ser Pro Arg Phe Glu Asp Ala Gly 
305                 310                 315                 320 


Val Tyr Ser Cys Ile Ala Met Asn Lys Gln Arg Leu Leu Asn Glu Thr 
                325                 330                 335     


Val Asp Val Thr Ile Asn Val Ser Asn Phe Thr Val Ser Arg Ser His 
            340                 345                 350         


Ala His Glu Ala Phe Asn Thr 
        355                 


<210>  36
<211>  364
<212>  PRT
<213>  Homo Sapiens

<400>  36

Thr Pro Asp Ser Glu Gly Phe Pro Pro Arg Ala Leu His Asn Cys Pro 
1               5                   10                  15      


Tyr Lys Cys Ile Cys Ala Ala Asp Leu Leu Ser Cys Thr Gly Leu Gly 
            20                  25                  30          


Leu Gln Asp Val Pro Ala Glu Leu Pro Ala Ala Thr Ala Asp Leu Asp 
        35                  40                  45              


Leu Ser His Asn Ala Leu Gln Arg Leu Arg Pro Gly Trp Leu Ala Pro 
    50                  55                  60                  


Leu Phe Gln Leu Arg Ala Leu His Leu Asp His Asn Glu Leu Asp Ala 
65                  70                  75                  80  


Leu Gly Arg Gly Val Phe Val Asn Ala Ser Gly Leu Arg Leu Leu Asp 
                85                  90                  95      


Leu Ser Ser Asn Thr Leu Arg Ala Leu Gly Arg His Asp Leu Asp Gly 
            100                 105                 110         


Leu Gly Ala Leu Glu Lys Leu Leu Leu Phe Asn Asn Arg Leu Val His 
        115                 120                 125             


Leu Asp Glu His Ala Phe His Gly Leu Arg Ala Leu Ser His Leu Tyr 
    130                 135                 140                 


Leu Gly Cys Asn Glu Leu Ala Ser Phe Ser Phe Asp His Leu His Gly 
145                 150                 155                 160 


Leu Ser Ala Thr His Leu Leu Thr Leu Asp Leu Ser Ser Asn Arg Leu 
                165                 170                 175     


Gly His Ile Ser Val Pro Glu Leu Ala Ala Leu Pro Ala Phe Leu Lys 
            180                 185                 190         


Asn Gly Leu Tyr Leu His Asn Asn Pro Leu Pro Cys Asp Cys Arg Leu 
        195                 200                 205             


Tyr His Leu Leu Gln Arg Trp His Gln Arg Gly Leu Ser Ala Val Arg 
    210                 215                 220                 


Asp Phe Ala Arg Glu Tyr Val Cys Leu Ala Phe Lys Val Pro Ala Ser 
225                 230                 235                 240 


Arg Val Arg Phe Phe Gln His Ser Arg Val Phe Glu Asn Cys Ser Ser 
                245                 250                 255     


Ala Pro Ala Leu Gly Leu Glu Arg Pro Glu Glu His Leu Tyr Ala Leu 
            260                 265                 270         


Val Gly Arg Ser Leu Arg Leu Tyr Cys Asn Thr Ser Val Pro Ala Met 
        275                 280                 285             


Arg Ile Ala Trp Val Ser Pro Gln Gln Glu Leu Leu Arg Ala Pro Gly 
    290                 295                 300                 


Ser Arg Asp Gly Ser Ile Ala Val Leu Ala Asp Gly Ser Leu Ala Ile 
305                 310                 315                 320 


Gly Asn Val Gln Glu Gln His Ala Gly Leu Phe Val Cys Leu Ala Thr 
                325                 330                 335     


Gly Pro Arg Leu His His Asn Gln Thr His Glu Tyr Asn Val Ser Val 
            340                 345                 350         


His Phe Pro Arg Pro Glu Pro Glu Ala Phe Asn Thr 
        355                 360                 


<210>  37
<211>  483
<212>  PRT
<213>  Homo Sapiens

<400>  37

His Ile Gly Cys Ser Asn Gln Arg Arg Ser Pro Glu Asn Ser Gly Arg 
1               5                   10                  15      


Arg Tyr Asn Arg Ile Gln His Gly Gln Cys Ala Tyr Thr Phe Ile Leu 
            20                  25                  30          


Pro Glu His Asp Gly Asn Cys Arg Glu Ser Thr Thr Asp Gln Tyr Asn 
        35                  40                  45              


Thr Asn Ala Leu Gln Arg Asp Ala Pro His Val Glu Pro Asp Phe Ser 
    50                  55                  60                  


Ser Gln Lys Leu Gln His Leu Glu His Val Met Glu Asn Tyr Thr Gln 
65                  70                  75                  80  


Trp Leu Gln Lys Leu Glu Asn Tyr Ile Val Glu Asn Met Lys Ser Glu 
                85                  90                  95      


Met Ala Gln Ile Gln Gln Asn Ala Val Gln Asn His Thr Ala Thr Met 
            100                 105                 110         


Leu Glu Ile Gly Thr Ser Leu Leu Ser Gln Thr Ala Glu Gln Thr Arg 
        115                 120                 125             


Lys Leu Thr Asp Val Glu Thr Gln Val Leu Asn Gln Thr Ser Arg Leu 
    130                 135                 140                 


Glu Ile Gln Leu Leu Glu Asn Ser Leu Ser Thr Tyr Lys Leu Glu Lys 
145                 150                 155                 160 


Gln Leu Leu Gln Gln Thr Asn Glu Ile Leu Lys Ile His Glu Lys Asn 
                165                 170                 175     


Ser Leu Leu Glu His Lys Ile Leu Glu Met Glu Gly Lys His Lys Glu 
            180                 185                 190         


Glu Leu Asp Thr Leu Lys Glu Glu Lys Glu Asn Leu Gln Gly Leu Val 
        195                 200                 205             


Thr Arg Gln Thr Tyr Ile Ile Gln Glu Leu Glu Lys Gln Leu Asn Arg 
    210                 215                 220                 


Ala Thr Thr Asn Asn Ser Val Leu Gln Lys Gln Gln Leu Glu Leu Met 
225                 230                 235                 240 


Asp Thr Val His Asn Leu Val Asn Leu Cys Thr Lys Glu Gly Val Leu 
                245                 250                 255     


Leu Lys Gly Gly Lys Arg Glu Glu Glu Lys Pro Phe Arg Asp Cys Ala 
            260                 265                 270         


Asp Val Tyr Gln Ala Gly Phe Asn Lys Ser Gly Ile Tyr Thr Ile Tyr 
        275                 280                 285             


Ile Asn Asn Met Pro Glu Pro Lys Lys Val Phe Cys Asn Met Asp Val 
    290                 295                 300                 


Asn Gly Gly Gly Trp Thr Val Ile Gln His Arg Glu Asp Gly Ser Leu 
305                 310                 315                 320 


Asp Phe Gln Arg Gly Trp Lys Glu Tyr Lys Met Gly Phe Gly Asn Pro 
                325                 330                 335     


Ser Gly Glu Tyr Trp Leu Gly Asn Glu Phe Ile Phe Ala Ile Thr Ser 
            340                 345                 350         


Gln Arg Gln Tyr Met Leu Arg Ile Glu Leu Met Asp Trp Glu Gly Asn 
        355                 360                 365             


Arg Ala Tyr Ser Gln Tyr Asp Arg Phe His Ile Gly Asn Glu Lys Gln 
    370                 375                 380                 


Asn Tyr Arg Leu Tyr Leu Lys Gly His Thr Gly Thr Ala Gly Lys Gln 
385                 390                 395                 400 


Ser Ser Leu Ile Leu His Gly Ala Asp Phe Ser Thr Lys Asp Ala Asp 
                405                 410                 415     


Asn Asp Asn Cys Met Cys Lys Cys Ala Leu Met Leu Thr Gly Gly Trp 
            420                 425                 430         


Trp Phe Asp Ala Cys Gly Pro Ser Asn Leu Asn Gly Met Phe Tyr Thr 
        435                 440                 445             


Ala Gly Gln Asn His Gly Lys Leu Asn Gly Ile Lys Trp His Tyr Phe 
    450                 455                 460                 


Lys Gly Pro Ser Tyr Ser Leu Arg Ser Thr Thr Met Met Ile Arg Pro 
465                 470                 475                 480 


Leu Asp Phe 
            


<210>  38
<211>  478
<212>  PRT
<213>  Homo Sapiens

<400>  38

Tyr Asn Asn Phe Arg Lys Ser Met Asp Ser Ile Gly Lys Lys Gln Tyr 
1               5                   10                  15      


Gln Val Gln His Gly Ser Cys Ser Tyr Thr Phe Leu Leu Pro Glu Met 
            20                  25                  30          


Asp Asn Cys Arg Ser Ser Ser Ser Pro Tyr Val Ser Asn Ala Val Gln 
        35                  40                  45              


Arg Asp Ala Pro Leu Glu Tyr Asp Asp Ser Val Gln Arg Leu Gln Val 
    50                  55                  60                  


Leu Glu Asn Ile Met Glu Asn Asn Thr Gln Trp Leu Met Lys Leu Glu 
65                  70                  75                  80  


Asn Tyr Ile Gln Asp Asn Met Lys Lys Glu Met Val Glu Ile Gln Gln 
                85                  90                  95      


Asn Ala Val Gln Asn Gln Thr Ala Val Met Ile Glu Ile Gly Thr Asn 
            100                 105                 110         


Leu Leu Asn Gln Thr Ala Glu Gln Thr Arg Lys Leu Thr Asp Val Glu 
        115                 120                 125             


Ala Gln Val Leu Asn Gln Thr Thr Arg Leu Glu Leu Gln Leu Leu Glu 
    130                 135                 140                 


His Ser Leu Ser Thr Asn Lys Leu Glu Lys Gln Ile Leu Asp Gln Thr 
145                 150                 155                 160 


Ser Glu Ile Asn Lys Leu Gln Asp Lys Asn Ser Phe Leu Glu Lys Lys 
                165                 170                 175     


Val Leu Ala Met Glu Asp Lys His Ile Ile Gln Leu Gln Ser Ile Lys 
            180                 185                 190         


Glu Glu Lys Asp Gln Leu Gln Val Leu Val Ser Lys Gln Asn Ser Ile 
        195                 200                 205             


Ile Glu Glu Leu Glu Lys Lys Ile Val Thr Ala Thr Val Asn Asn Ser 
    210                 215                 220                 


Val Leu Gln Lys Gln Gln His Asp Leu Met Glu Thr Val Asn Asn Leu 
225                 230                 235                 240 


Leu Thr Met Met Ser Thr Ser Asn Ser Ala Lys Asp Pro Thr Val Ala 
                245                 250                 255     


Lys Glu Glu Gln Ile Ser Phe Arg Asp Cys Ala Glu Val Phe Lys Ser 
            260                 265                 270         


Gly His Thr Thr Asn Gly Ile Tyr Thr Leu Thr Phe Pro Asn Ser Thr 
        275                 280                 285             


Glu Glu Ile Lys Ala Tyr Cys Asp Met Glu Ala Gly Gly Gly Gly Trp 
    290                 295                 300                 


Thr Ile Ile Gln Arg Arg Glu Asp Gly Ser Val Asp Phe Gln Arg Thr 
305                 310                 315                 320 


Trp Lys Glu Tyr Lys Val Gly Phe Gly Asn Pro Ser Gly Glu Tyr Trp 
                325                 330                 335     


Leu Gly Asn Glu Phe Val Ser Gln Leu Thr Asn Gln Gln Arg Tyr Val 
            340                 345                 350         


Leu Lys Ile His Leu Lys Asp Trp Glu Gly Asn Glu Ala Tyr Ser Leu 
        355                 360                 365             


Tyr Glu His Phe Tyr Leu Ser Ser Glu Glu Leu Asn Tyr Arg Ile His 
    370                 375                 380                 


Leu Lys Gly Leu Thr Gly Thr Ala Gly Lys Ile Ser Ser Ile Ser Gln 
385                 390                 395                 400 


Pro Gly Asn Asp Phe Ser Thr Lys Asp Gly Asp Asn Asp Lys Cys Ile 
                405                 410                 415     


Cys Lys Cys Ser Gln Met Leu Thr Gly Gly Trp Trp Phe Asp Ala Cys 
            420                 425                 430         


Gly Pro Ser Asn Leu Asn Gly Met Tyr Tyr Pro Gln Arg Gln Asn Thr 
        435                 440                 445             


Asn Lys Phe Asn Gly Ile Lys Trp Tyr Tyr Trp Lys Gly Ser Gly Tyr 
    450                 455                 460                 


Ser Leu Lys Ala Thr Thr Met Met Ile Arg Pro Ala Asp Phe 
465                 470                 475             


<210>  39
<211>  479
<212>  PRT
<213>  Homo Sapiens

<400>  39

Thr Arg Gln Glu Ala Asp Arg Gly Cys Glu Thr Leu Val Val Gln His 
1               5                   10                  15      


Gly His Cys Ser Tyr Thr Phe Leu Leu Pro Lys Ser Glu Pro Cys Pro 
            20                  25                  30          


Pro Gly Pro Glu Val Ser Arg Asp Ser Asn Thr Leu Gln Arg Glu Ser 
        35                  40                  45              


Leu Ala Asn Pro Leu His Leu Gly Lys Leu Pro Thr Gln Gln Val Lys 
    50                  55                  60                  


Gln Leu Glu Gln Ala Leu Gln Asn Asn Thr Gln Trp Leu Lys Lys Leu 
65                  70                  75                  80  


Glu Arg Ala Ile Lys Thr Ile Leu Arg Ser Lys Leu Glu Gln Val Gln 
                85                  90                  95      


Gln Gln Met Ala Gln Asn Gln Thr Ala Pro Met Leu Glu Leu Gly Thr 
            100                 105                 110         


Ser Leu Leu Asn Gln Thr Thr Ala Gln Ile Arg Lys Leu Thr Asp Met 
        115                 120                 125             


Glu Ala Gln Leu Leu Asn Gln Thr Ser Arg Met Asp Ala Gln Met Pro 
    130                 135                 140                 


Glu Thr Phe Leu Ser Thr Asn Lys Leu Glu Asn Gln Leu Leu Leu Gln 
145                 150                 155                 160 


Arg Gln Lys Leu Gln Gln Leu Gln Gly Gln Asn Ser Ala Leu Glu Lys 
                165                 170                 175     


Arg Leu Gln Ala Leu Glu Thr Lys Gln Gln Glu Glu Leu Ala Ser Ile 
            180                 185                 190         


Leu Ser Lys Lys Ala Lys Leu Leu Asn Thr Leu Ser Arg Gln Ser Ala 
        195                 200                 205             


Ala Leu Thr Asn Ile Glu Arg Gly Leu Arg Gly Val Arg His Asn Ser 
    210                 215                 220                 


Ser Leu Leu Gln Asp Gln Gln His Ser Leu Arg Gln Leu Leu Val Leu 
225                 230                 235                 240 


Leu Arg His Leu Val Gln Glu Arg Ala Asn Ala Ser Ala Pro Ala Phe 
                245                 250                 255     


Ile Met Ala Gly Glu Gln Val Phe Gln Asp Cys Ala Glu Ile Gln Arg 
            260                 265                 270         


Ser Gly Ala Ser Ala Ser Gly Val Tyr Thr Ile Gln Val Ser Asn Ala 
        275                 280                 285             


Thr Lys Pro Arg Lys Val Phe Cys Asp Leu Gln Ser Ser Gly Gly Arg 
    290                 295                 300                 


Trp Thr Leu Ile Gln Arg Arg Glu Asn Gly Thr Val Asn Phe Gln Arg 
305                 310                 315                 320 


Asn Trp Lys Asp Tyr Lys Gln Gly Phe Gly Asp Pro Ala Gly Glu His 
                325                 330                 335     


Trp Leu Gly Asn Glu Val Val His Gln Leu Thr Arg Arg Ala Ala Tyr 
            340                 345                 350         


Ser Leu Arg Val Glu Leu Gln Asp Trp Glu Gly His Glu Ala Tyr Ala 
        355                 360                 365             


Gln Tyr Glu His Phe His Leu Gly Ser Glu Asn Gln Leu Tyr Arg Leu 
    370                 375                 380                 


Ser Val Val Gly Tyr Ser Gly Ser Ala Gly Arg Gln Ser Ser Leu Val 
385                 390                 395                 400 


Leu Gln Asn Thr Ser Phe Ser Thr Leu Asp Ser Asp Asn Asp His Cys 
                405                 410                 415     


Leu Cys Lys Cys Ala Gln Val Met Ser Gly Gly Trp Trp Phe Asp Ala 
            420                 425                 430         


Cys Gly Leu Ser Asn Leu Asn Gly Val Tyr Tyr His Ala Pro Asp Asn 
        435                 440                 445             


Lys Tyr Lys Met Asp Gly Ile Arg Trp His Tyr Phe Lys Gly Pro Ser 
    450                 455                 460                 


Tyr Ser Leu Arg Ala Ser Arg Met Met Ile Arg Pro Leu Asp Ile 
465                 470                 475                 


<210>  40
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  40

Gln Glu Asp Gly Phe Glu Gly Thr Glu Glu Gly Ser Pro Arg Glu Phe 
1               5                   10                  15      


Ile Tyr Leu Asn Arg Tyr Lys Arg Ala Gly Glu Ser Gln Asp Lys Cys 
            20                  25                  30          


Thr Tyr Thr Phe Ile Val Pro Gln Gln Arg Val Thr Gly Ala Ile Cys 
        35                  40                  45              


Val Asn Ser Lys Glu Pro Glu Val Leu Leu Glu Asn Arg Val His Lys 
    50                  55                  60                  


Gln Glu Leu Glu Leu Leu Asn Asn Glu Leu Leu Lys Gln Lys Arg Gln 
65                  70                  75                  80  


Ile Glu Thr Leu Gln Gln Leu Val Glu Val Asp Gly Gly Ile Val Ser 
                85                  90                  95      


Glu Val Lys Leu Leu Arg Lys Glu Ser Arg Asn Met Asn Ser Arg Val 
            100                 105                 110         


Thr Gln Leu Tyr Met Gln Leu Leu His Glu Ile Ile Arg Lys Arg Asp 
        115                 120                 125             


Asn Ala Leu Glu Leu Ser Gln Leu Glu Asn Arg Ile Leu Asn Gln Thr 
    130                 135                 140                 


Ala Asp Met Leu Gln Leu Ala Ser Lys Tyr Lys Asp Leu Glu His Lys 
145                 150                 155                 160 


Tyr Gln His Leu Ala Thr Leu Ala His Asn Gln Ser Glu Ile Ile Ala 
                165                 170                 175     


Gln Leu Glu Glu His Cys Gln Arg Val Pro Ser Ala Arg Pro Val Pro 
            180                 185                 190         


Gln Pro Pro Pro Ala Ala Pro Pro Arg Val Tyr Gln Pro Pro Thr Tyr 
        195                 200                 205             


Asn Arg Ile Ile Asn Gln Ile Ser Thr Asn Glu Ile Gln Ser Asp Gln 
    210                 215                 220                 


Asn Leu Lys Val Leu Pro Pro Pro Leu Pro Thr Met Pro Thr Leu Thr 
225                 230                 235                 240 


Ser Leu Pro Ser Ser Thr Asp Lys Pro Ser Gly Pro Trp Arg Asp Cys 
                245                 250                 255     


Leu Gln Ala Leu Glu Asp Gly His Asp Thr Ser Ser Ile Tyr Leu Val 
            260                 265                 270         


Lys Pro Glu Asn Thr Asn Arg Leu Met Gln Val Trp Cys Asp Gln Arg 
        275                 280                 285             


His Asp Pro Gly Gly Trp Thr Val Ile Gln Arg Arg Leu Asp Gly Ser 
    290                 295                 300                 


Val Asn Phe Phe Arg Asn Trp Glu Thr Tyr Lys Gln Gly Phe Gly Asn 
305                 310                 315                 320 


Ile Asp Gly Glu Tyr Trp Leu Gly Leu Glu Asn Ile Tyr Trp Leu Thr 
                325                 330                 335     


Asn Gln Gly Asn Tyr Lys Leu Leu Val Thr Met Glu Asp Trp Ser Gly 
            340                 345                 350         


Arg Lys Val Phe Ala Glu Tyr Ala Ser Phe Arg Leu Glu Pro Glu Ser 
        355                 360                 365             


Glu Tyr Tyr Lys Leu Arg Leu Gly Arg Tyr His Gly Asn Ala Gly Asp 
    370                 375                 380                 


Ser Phe Thr Trp His Asn Gly Lys Gln Phe Thr Thr Leu Asp Arg Asp 
385                 390                 395                 400 


His Asp Val Tyr Thr Gly Asn Cys Ala His Tyr Gln Lys Gly Gly Trp 
                405                 410                 415     


Trp Tyr Asn Ala Cys Ala His Ser Asn Leu Asn Gly Val Trp Tyr Arg 
            420                 425                 430         


Gly Gly His Tyr Arg Ser Arg Tyr Gln Asp Gly Val Tyr Trp Ala Glu 
        435                 440                 445             


Phe Arg Gly Gly Ser Tyr Ser Leu Lys Lys Val Val Met Met Ile Arg 
    450                 455                 460                 


Pro Asn Pro Asn Thr Phe His 
465                 470     


<210>  41
<211>  444
<212>  PRT
<213>  Homo Sapiens

<400>  41

Ser Arg Ile Asp Gln Asp Asn Ser Ser Phe Asp Ser Leu Ser Pro Glu 
1               5                   10                  15      


Pro Lys Ser Arg Phe Ala Met Leu Asp Asp Val Lys Ile Leu Ala Asn 
            20                  25                  30          


Gly Leu Leu Gln Leu Gly His Gly Leu Lys Asp Phe Val His Lys Thr 
        35                  40                  45              


Lys Gly Gln Ile Asn Asp Ile Phe Gln Lys Leu Asn Ile Phe Asp Gln 
    50                  55                  60                  


Ser Phe Tyr Asp Leu Ser Leu Gln Thr Ser Glu Ile Lys Glu Glu Glu 
65                  70                  75                  80  


Lys Glu Leu Arg Arg Thr Thr Tyr Lys Leu Gln Val Lys Asn Glu Glu 
                85                  90                  95      


Val Lys Asn Met Ser Leu Glu Leu Asn Ser Lys Leu Glu Ser Leu Leu 
            100                 105                 110         


Glu Glu Lys Ile Leu Leu Gln Gln Lys Val Lys Tyr Leu Glu Glu Gln 
        115                 120                 125             


Leu Thr Asn Leu Ile Gln Asn Gln Pro Glu Thr Pro Glu His Pro Glu 
    130                 135                 140                 


Val Thr Ser Leu Lys Thr Phe Val Glu Lys Gln Asp Asn Ser Ile Lys 
145                 150                 155                 160 


Asp Leu Leu Gln Thr Val Glu Asp Gln Tyr Lys Gln Leu Asn Gln Gln 
                165                 170                 175     


His Ser Gln Ile Lys Glu Ile Glu Asn Gln Leu Arg Arg Thr Ser Ile 
            180                 185                 190         


Gln Glu Pro Thr Glu Ile Ser Leu Ser Ser Lys Pro Arg Ala Pro Arg 
        195                 200                 205             


Thr Thr Pro Phe Leu Gln Leu Asn Glu Ile Arg Asn Val Lys His Asp 
    210                 215                 220                 


Gly Ile Pro Ala Glu Cys Thr Thr Ile Tyr Asn Arg Gly Glu His Thr 
225                 230                 235                 240 


Ser Gly Met Tyr Ala Ile Arg Pro Ser Asn Ser Gln Val Phe His Val 
                245                 250                 255     


Tyr Cys Asp Val Ile Ser Gly Ser Pro Trp Thr Leu Ile Gln His Arg 
            260                 265                 270         


Ile Asp Gly Ser Gln Asn Phe Asn Glu Thr Trp Glu Asn Tyr Lys Tyr 
        275                 280                 285             


Gly Phe Gly Arg Leu Asp Gly Glu Phe Trp Leu Gly Leu Glu Lys Ile 
    290                 295                 300                 


Tyr Ser Ile Val Lys Gln Ser Asn Tyr Val Leu Arg Ile Glu Leu Glu 
305                 310                 315                 320 


Asp Trp Lys Asp Asn Lys His Tyr Ile Glu Tyr Ser Phe Tyr Leu Gly 
                325                 330                 335     


Asn His Glu Thr Asn Tyr Thr Leu His Leu Val Ala Ile Thr Gly Asn 
            340                 345                 350         


Val Pro Asn Ala Ile Pro Glu Asn Lys Asp Leu Val Phe Ser Thr Trp 
        355                 360                 365             


Asp His Lys Ala Lys Gly His Phe Asn Cys Pro Glu Gly Tyr Ser Gly 
    370                 375                 380                 


Gly Trp Trp Trp His Asp Glu Cys Gly Glu Asn Asn Leu Asn Gly Lys 
385                 390                 395                 400 


Tyr Asn Lys Pro Arg Ala Lys Ser Lys Pro Glu Arg Arg Arg Gly Leu 
                405                 410                 415     


Ser Trp Lys Ser Gln Asn Gly Arg Leu Tyr Ser Ile Lys Ser Thr Lys 
            420                 425                 430         


Met Leu Ile His Pro Thr Asp Ser Glu Ser Phe Glu 
        435                 440                 


<210>  42
<211>  381
<212>  PRT
<213>  Homo Sapiens

<400>  42

Gly Pro Val Gln Ser Lys Ser Pro Arg Phe Ala Ser Trp Asp Glu Met 
1               5                   10                  15      


Asn Val Leu Ala His Gly Leu Leu Gln Leu Gly Gln Gly Leu Arg Glu 
            20                  25                  30          


His Ala Glu Arg Thr Arg Ser Gln Leu Ser Ala Leu Glu Arg Arg Leu 
        35                  40                  45              


Ser Ala Cys Gly Ser Ala Cys Gln Gly Thr Glu Gly Ser Thr Asp Leu 
    50                  55                  60                  


Pro Leu Ala Pro Glu Ser Arg Val Asp Pro Glu Val Leu His Ser Leu 
65                  70                  75                  80  


Gln Thr Gln Leu Lys Ala Gln Asn Ser Arg Ile Gln Gln Leu Phe His 
                85                  90                  95      


Lys Val Ala Gln Gln Gln Arg His Leu Glu Lys Gln His Leu Arg Ile 
            100                 105                 110         


Gln His Leu Gln Ser Gln Phe Gly Leu Leu Asp His Lys His Leu Asp 
        115                 120                 125             


His Glu Val Ala Lys Pro Ala Arg Arg Lys Arg Leu Pro Glu Met Ala 
    130                 135                 140                 


Gln Pro Val Asp Pro Ala His Asn Val Ser Arg Leu His Arg Leu Pro 
145                 150                 155                 160 


Arg Asp Cys Gln Glu Leu Phe Gln Val Gly Glu Arg Gln Ser Gly Leu 
                165                 170                 175     


Phe Glu Ile Gln Pro Gln Gly Ser Pro Pro Phe Leu Val Asn Cys Lys 
            180                 185                 190         


Met Thr Ser Asp Gly Gly Trp Thr Val Ile Gln Arg Arg His Asp Gly 
        195                 200                 205             


Ser Val Asp Phe Asn Arg Pro Trp Glu Ala Tyr Lys Ala Gly Phe Gly 
    210                 215                 220                 


Asp Pro His Gly Glu Phe Trp Leu Gly Leu Glu Lys Val His Ser Ile 
225                 230                 235                 240 


Thr Gly Asp Arg Asn Ser Arg Leu Ala Val Gln Leu Arg Asp Trp Asp 
                245                 250                 255     


Gly Asn Ala Glu Leu Leu Gln Phe Ser Val His Leu Gly Gly Glu Asp 
            260                 265                 270         


Thr Ala Tyr Ser Leu Gln Leu Thr Ala Pro Val Ala Gly Gln Leu Gly 
        275                 280                 285             


Ala Thr Thr Val Pro Pro Ser Gly Leu Ser Val Pro Phe Ser Thr Trp 
    290                 295                 300                 


Asp Gln Asp His Asp Leu Arg Arg Asp Lys Asn Cys Ala Lys Ser Leu 
305                 310                 315                 320 


Ser Gly Gly Trp Trp Phe Gly Thr Cys Ser His Ser Asn Leu Asn Gly 
                325                 330                 335     


Gln Tyr Phe Arg Ser Ile Pro Gln Gln Arg Gln Lys Leu Lys Lys Gly 
            340                 345                 350         


Ile Phe Trp Lys Thr Trp Arg Gly Arg Tyr Tyr Pro Leu Gln Ala Thr 
        355                 360                 365             


Thr Met Leu Ile Gln Pro Met Ala Ala Glu Ala Ala Ser 
    370                 375                 380     


<210>  43
<211>  301
<212>  PRT
<213>  Homo Sapiens

<400>  43

Glu Asp Gly Gly Pro Ala Cys Tyr Gly Gly Phe Asp Leu Tyr Phe Ile 
1               5                   10                  15      


Leu Asp Lys Ser Gly Ser Val Leu His His Trp Asn Glu Ile Tyr Tyr 
            20                  25                  30          


Phe Val Glu Gln Leu Ala His Lys Phe Ile Ser Pro Gln Leu Arg Met 
        35                  40                  45              


Ser Phe Ile Val Phe Ser Thr Arg Gly Thr Thr Leu Met Lys Leu Thr 
    50                  55                  60                  


Glu Asp Arg Glu Gln Ile Arg Gln Gly Leu Glu Glu Leu Gln Lys Val 
65                  70                  75                  80  


Leu Pro Gly Gly Asp Thr Tyr Met His Glu Gly Phe Glu Arg Ala Ser 
                85                  90                  95      


Glu Gln Ile Tyr Tyr Glu Asn Arg Gln Gly Tyr Arg Thr Ala Ser Val 
            100                 105                 110         


Ile Ile Ala Leu Thr Asp Gly Glu Leu His Glu Asp Leu Phe Phe Tyr 
        115                 120                 125             


Ser Glu Arg Glu Ala Asn Arg Ser Arg Asp Leu Gly Ala Ile Val Tyr 
    130                 135                 140                 


Cys Val Gly Val Lys Asp Phe Asn Glu Thr Gln Leu Ala Arg Ile Ala 
145                 150                 155                 160 


Asp Ser Lys Asp His Val Phe Pro Val Asn Asp Gly Phe Gln Ala Leu 
                165                 170                 175     


Gln Gly Ile Ile His Ser Ile Leu Lys Lys Ser Cys Ile Glu Ile Leu 
            180                 185                 190         


Ala Ala Glu Pro Ser Thr Ile Cys Ala Gly Glu Ser Phe Gln Val Val 
        195                 200                 205             


Val Arg Gly Asn Gly Phe Arg His Ala Arg Asn Val Asp Arg Val Leu 
    210                 215                 220                 


Cys Ser Phe Lys Ile Asn Asp Ser Val Thr Leu Asn Glu Lys Pro Phe 
225                 230                 235                 240 


Ser Val Glu Asp Thr Tyr Leu Leu Cys Pro Ala Pro Ile Leu Lys Glu 
                245                 250                 255     


Val Gly Met Lys Ala Ala Leu Gln Val Ser Met Asn Asp Gly Leu Ser 
            260                 265                 270         


Phe Ile Ser Ser Ser Val Ile Ile Thr Thr Thr His Cys Ser Leu His 
        275                 280                 285             


Lys Ile Ala Ser Gly Pro Thr Thr Ala Ala Cys Met Glu 
    290                 295                 300     


<210>  44
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  44

Gln Glu Gln Pro Ser Cys Arg Arg Ala Phe Asp Leu Tyr Phe Val Leu 
1               5                   10                  15      


Asp Lys Ser Gly Ser Val Ala Asn Asn Trp Ile Glu Ile Tyr Asn Phe 
            20                  25                  30          


Val Gln Gln Leu Ala Glu Arg Phe Val Ser Pro Glu Met Arg Leu Ser 
        35                  40                  45              


Phe Ile Val Phe Ser Ser Gln Ala Thr Ile Ile Leu Pro Leu Thr Gly 
    50                  55                  60                  


Asp Arg Gly Lys Ile Ser Lys Gly Leu Glu Asp Leu Lys Arg Val Ser 
65                  70                  75                  80  


Pro Val Gly Glu Thr Tyr Ile His Glu Gly Leu Lys Leu Ala Asn Glu 
                85                  90                  95      


Gln Ile Gln Lys Ala Gly Gly Leu Lys Thr Ser Ser Ile Ile Ile Ala 
            100                 105                 110         


Leu Thr Asp Gly Lys Leu Asp Gly Leu Val Pro Ser Tyr Ala Glu Lys 
        115                 120                 125             


Glu Ala Lys Ile Ser Arg Ser Leu Gly Ala Ser Val Tyr Cys Val Gly 
    130                 135                 140                 


Val Leu Asp Phe Glu Gln Ala Gln Leu Glu Arg Ile Ala Asp Ser Lys 
145                 150                 155                 160 


Glu Gln Val Phe Pro Val Lys Gly Gly Phe Gln Ala Leu Lys Gly Ile 
                165                 170                 175     


Ile Asn Ser Ile Leu Ala Gln Ser Cys Thr Glu Ile Leu Glu Leu Gln 
            180                 185                 190         


Pro Ser Ser Val Cys Val Gly Glu Glu Phe Gln Ile Val Leu Ser Gly 
        195                 200                 205             


Arg Gly Phe Met Leu Gly Ser Arg Asn Gly Ser Val Leu Cys Thr Tyr 
    210                 215                 220                 


Thr Val Asn Glu Thr Tyr Thr Thr Ser Val Lys Pro Val Ser Val Gln 
225                 230                 235                 240 


Leu Asn Ser Met Leu Cys Pro Ala Pro Ile Leu Asn Lys Ala Gly Glu 
                245                 250                 255     


Thr Leu Asp Val Ser Val Ser Phe Asn Gly Gly Lys Ser Val Ile Ser 
            260                 265                 270         


Gly Ser Leu Ile Val Thr Ala Thr Glu Cys Ser Asn Gly 
        275                 280                 285 


<210>  45
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  45

Gly Ser Leu Arg Tyr His Gly Pro Asp Trp Arg Ile Phe His Arg Leu 
1               5                   10                  15      


Ala Leu Gly Ser Arg Arg Ala His His His His Gly Pro Gly Trp Arg 
            20                  25                  30          


Gln His Trp Arg Gln Gly Gln Ala Gly His Arg Cys Gln Gly Ser Phe 
        35                  40                  45              


Asp Leu Tyr Phe Ile Leu Asp Lys Ser Gly Ser Val Asn Asn Asn Trp 
    50                  55                  60                  


Ile Asp Leu Tyr Met Trp Val Glu Glu Thr Val Ala Arg Phe Gln Ser 
65                  70                  75                  80  


Pro Asn Ile Arg Met Cys Phe Ile Thr Tyr Ser Thr Asp Gly Gln Thr 
                85                  90                  95      


Val Leu Pro Leu Thr Ser Asp Lys Asn Arg Ile Lys Asn Gly Leu Asp 
            100                 105                 110         


Gln Leu Gln Lys Ile Val Pro Asp Gly His Thr Phe Met Gln Ala Gly 
        115                 120                 125             


Phe Arg Lys Ala Ile Gln Gln Ile Glu Ser Phe Asn Ser Gly Asn Lys 
    130                 135                 140                 


Val Pro Ser Met Ile Ile Ala Met Thr Asp Gly Glu Leu Val Ala His 
145                 150                 155                 160 


Ala Phe Gln Asp Thr Leu Arg Glu Ala Gln Lys Ala Arg Lys Leu Gly 
                165                 170                 175     


Ala Asn Val Tyr Thr Leu Gly Val Ala Asp Tyr Asn Leu Asp Gln Ile 
            180                 185                 190         


Thr Ala Ile Ala Asp Ser Pro Gly His Val Phe Ala Val Glu Asn Gly 
        195                 200                 205             


Phe Lys Ala Leu Arg Ser Thr Ile Asp Ala Leu Thr Ser Lys Val Cys 
    210                 215                 220                 


Leu Asp Val Thr Ser Val Glu Pro Ser Ser Glu Cys Val Gly Glu Pro 
225                 230                 235                 240 


Tyr His Val Val Ile His Gly Asn Gly Phe Gln Asn Leu Lys Lys Arg 
                245                 250                 255     


Asp Glu Val Ile Cys Arg Phe Ile Phe Asn Glu Ser Thr Ile Ile Asp 
            260                 265                 270         


Glu Lys Pro Thr Ser Ile Asp Asn Asn Ser Met Asn Cys Pro Gly Pro 
        275                 280                 285             


Lys Leu Glu Lys Pro Gly Glu Glu Tyr Ser Ile Glu Val Ser Leu Asn 
    290                 295                 300                 


Lys Gly Lys Thr Phe Phe Lys Ser Asn Val Ser Ile Thr Ser Thr Thr 
305                 310                 315                 320 


Cys Gly Ile Phe Arg Asn 
                325     


<210>  46
<211>  87
<212>  PRT
<213>  Homo Sapiens

<400>  46

Ser Val Arg Val Glu Gln Val Val Lys Pro Pro Gln Asn Lys Thr Glu 
1               5                   10                  15      


Ser Glu Asn Thr Ser Asp Lys Pro Lys Arg Lys Lys Lys Gly Gly Lys 
            20                  25                  30          


Asn Gly Lys Asn Arg Arg Asn Arg Lys Lys Lys Asn Pro Cys Asn Ala 
        35                  40                  45              


Glu Phe Gln Asn Phe Cys Ile His Gly Glu Cys Lys Tyr Ile Glu His 
    50                  55                  60                  


Leu Glu Ala Val Thr Cys Lys Cys Gln Gln Glu Tyr Phe Gly Glu Arg 
65                  70                  75                  80  


Cys Gly Glu Lys Ser Met Lys 
                85          


<210>  47
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  47

Thr His Thr Glu Ile Lys Arg Val Ala Glu Glu Lys Val Thr Leu Pro 
1               5                   10                  15      


Cys His His Gln Leu Gly Leu Pro Glu Lys Asp Thr Leu Asp Ile Glu 
            20                  25                  30          


Trp Leu Leu Thr Asp Asn Glu Gly Asn Gln Lys Val Val Ile Thr Tyr 
        35                  40                  45              


Ser Ser Arg His Val Tyr Asn Asn Leu Thr Glu Glu Gln Lys Gly Arg 
    50                  55                  60                  


Val Ala Phe Ala Ser Asn Phe Leu Ala Gly Asp Ala Ser Leu Gln Ile 
65                  70                  75                  80  


Glu Pro Leu Lys Pro Ser Asp Glu Gly Arg Tyr Thr Cys Lys Val Lys 
                85                  90                  95      


Asn Ser Gly Arg Tyr Val Trp Ser His Val Ile Leu Lys Val Leu Val 
            100                 105                 110         


Arg Pro Ser Lys Pro Lys Cys Glu Leu Glu Gly Glu Leu Thr Glu Gly 
        115                 120                 125             


Ser Asp Leu Thr Leu Gln Cys Glu Ser Ser Ser Gly Thr Glu Pro Ile 
    130                 135                 140                 


Val Tyr Tyr Trp Gln Arg Ile Arg Glu Lys Glu Gly Glu Asp Glu Arg 
145                 150                 155                 160 


Leu Pro Pro Lys Ser Arg Ile Asp Tyr Asn His Pro Gly Arg Val Leu 
                165                 170                 175     


Leu Gln Asn Leu Thr Met Ser Tyr Ser Gly Leu Tyr Gln Cys Thr Ala 
            180                 185                 190         


Gly Asn Glu Ala Gly Lys Glu Ser Cys Val Val Arg Val Thr Val Gln 
        195                 200                 205             


Tyr Val Gln Ser Ile Gly Met Val Ala 
    210                 215         


<210>  48
<211>  230
<212>  PRT
<213>  Homo Sapiens

<400>  48

Gln Asn Ser Gln Leu Gln Glu Glu Leu Arg Gly Leu Arg Glu Thr Phe 
1               5                   10                  15      


Ser Asn Phe Thr Ala Ser Thr Glu Ala Gln Val Lys Gly Leu Ser Thr 
            20                  25                  30          


Gln Gly Gly Asn Val Gly Arg Lys Met Lys Ser Leu Glu Ser Gln Leu 
        35                  40                  45              


Glu Lys Gln Gln Lys Asp Leu Ser Glu Asp His Ser Ser Leu Leu Leu 
    50                  55                  60                  


His Val Lys Gln Phe Val Ser Asp Leu Arg Ser Leu Ser Cys Gln Met 
65                  70                  75                  80  


Ala Ala Leu Gln Gly Asn Gly Ser Glu Arg Thr Cys Cys Pro Val Asn 
                85                  90                  95      


Trp Val Glu His Glu Arg Ser Cys Tyr Trp Phe Ser Arg Ser Gly Lys 
            100                 105                 110         


Ala Trp Ala Asp Ala Asp Asn Tyr Cys Arg Leu Glu Asp Ala His Leu 
        115                 120                 125             


Val Val Val Thr Ser Trp Glu Glu Gln Lys Phe Val Gln His His Ile 
    130                 135                 140                 


Gly Pro Val Asn Thr Trp Met Gly Leu His Asp Gln Asn Gly Pro Trp 
145                 150                 155                 160 


Lys Trp Val Asp Gly Thr Asp Tyr Glu Thr Gly Phe Lys Asn Trp Arg 
                165                 170                 175     


Pro Glu Gln Pro Asp Asp Trp Tyr Gly His Gly Leu Gly Gly Gly Glu 
            180                 185                 190         


Asp Cys Ala His Phe Thr Asp Asp Gly Arg Trp Asn Asp Asp Val Cys 
        195                 200                 205             


Gln Arg Pro Tyr Arg Trp Val Cys Glu Thr Glu Leu Asp Lys Ala Ser 
    210                 215                 220                 


Gln Glu Pro Pro Leu Leu 
225                 230 


<210>  49
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  49

Gln Ser Ala Gln Leu Gln Ala Glu Leu Arg Ser Leu Lys Glu Ala Phe 
1               5                   10                  15      


Ser Asn Phe Ser Ser Ser Thr Leu Thr Glu Val Gln Ala Ile Ser Thr 
            20                  25                  30          


His Gly Gly Ser Val Gly Asp Lys Ile Thr Ser Leu Gly Ala Lys Leu 
        35                  40                  45              


Glu Lys Gln Gln Gln Asp Leu Lys Ala Asp His Asp Ala Leu Leu Phe 
    50                  55                  60                  


His Leu Lys His Phe Pro Val Asp Leu Arg Phe Val Ala Cys Gln Met 
65                  70                  75                  80  


Glu Leu Leu His Ser Asn Gly Ser Gln Arg Thr Cys Cys Pro Val Asn 
                85                  90                  95      


Trp Val Glu His Gln Gly Ser Cys Tyr Trp Phe Ser His Ser Gly Lys 
            100                 105                 110         


Ala Trp Ala Glu Ala Glu Lys Tyr Cys Gln Leu Glu Asn Ala His Leu 
        115                 120                 125             


Val Val Ile Asn Ser Trp Glu Glu Gln Lys Phe Ile Val Gln His Thr 
    130                 135                 140                 


Asn Pro Phe Asn Thr Trp Ile Gly Leu Thr Asp Ser Asp Gly Ser Trp 
145                 150                 155                 160 


Lys Trp Val Asp Gly Thr Asp Tyr Arg His Asn Tyr Lys Asn Trp Ala 
                165                 170                 175     


Val Thr Gln Pro Asp Asn Trp His Gly His Glu Leu Gly Gly Ser Glu 
            180                 185                 190         


Asp Cys Val Glu Val Gln Pro Asp Gly Arg Trp Asn Asp Asp Phe Cys 
        195                 200                 205             


Leu Gln Val Tyr Arg Trp Val Cys Glu Lys Arg Arg Asn Ala Thr Gly 
    210                 215                 220                 


Glu Val Ala 
225         


<210>  50
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  50

Asp Met Glu Asp Thr Asp Asp Asp Asp Asp Asp Asp Asp Asp Asp Asp 
1               5                   10                  15      


Asp Asp Asp Asp Asp Asp Glu Glu Asp Asn Ser Leu Phe Pro Thr Arg 
            20                  25                  30          


Glu Pro Arg Ser His Phe Phe Pro Phe Asp Leu Phe Pro Met Cys Pro 
        35                  40                  45              


Phe Gly Cys Gln Cys Tyr Ser Arg Val Val His Cys Ser Asp Leu Gly 
    50                  55                  60                  


Leu Thr Ser Val Pro Thr Asn Ile Pro Phe Asp Thr Arg Met Leu Asp 
65                  70                  75                  80  


Leu Gln Asn Asn Lys Ile Lys Glu Ile Lys Glu Asn Asp Phe Lys Gly 
                85                  90                  95      


Leu Thr Ser Leu Tyr Gly Leu Ile Leu Asn Asn Asn Lys Leu Thr Lys 
            100                 105                 110         


Ile His Pro Lys Ala Phe Leu Thr Thr Lys Lys Leu Arg Arg Leu Tyr 
        115                 120                 125             


Leu Ser His Asn Gln Leu Ser Glu Ile Pro Leu Asn Leu Pro Lys Ser 
    130                 135                 140                 


Leu Ala Glu Leu Arg Ile His Glu Asn Lys Val Lys Lys Ile Gln Lys 
145                 150                 155                 160 


Asp Thr Phe Lys Gly Met Asn Ala Leu His Val Leu Glu Met Ser Ala 
                165                 170                 175     


Asn Pro Leu Asp Asn Asn Gly Ile Glu Pro Gly Ala Phe Glu Gly Val 
            180                 185                 190         


Thr Val Phe His Ile Arg Ile Ala Glu Ala Lys Leu Thr Ser Val Pro 
        195                 200                 205             


Lys Gly Leu Pro Pro Thr Leu Leu Glu Leu His Leu Asp Tyr Asn Lys 
    210                 215                 220                 


Ile Ser Thr Val Glu Leu Glu Asp Phe Lys Arg Tyr Lys Glu Leu Gln 
225                 230                 235                 240 


Arg Leu Gly Leu Gly Asn Asn Lys Ile Thr Asp Ile Glu Asn Gly Ser 
                245                 250                 255     


Leu Ala Asn Ile Pro Arg Val Arg Glu Ile His Leu Glu Asn Asn Lys 
            260                 265                 270         


Leu Lys Lys Ile Pro Ser Gly Leu Pro Glu Leu Lys Tyr Leu Gln Ile 
        275                 280                 285             


Ile Phe Leu His Ser Asn Ser Ile Ala Arg Val Gly Val Asn Asp Phe 
    290                 295                 300                 


Cys Pro Thr Val Pro Lys Met Lys Lys Ser Leu Tyr Ser Ala Ile Ser 
305                 310                 315                 320 


Leu Phe Asn Asn Pro Val Lys Tyr Trp Glu Met Gln Pro Ala Thr Phe 
                325                 330                 335     


Arg Cys Val Leu Ser Arg Met Ser Val Gln Leu Gly Asn Phe Gly Met 
            340                 345                 350         


<210>  51
<211>  814
<212>  PRT
<213>  Homo Sapiens

<400>  51

His Val Asn Cys Pro Leu Val Val Lys Ile Thr Leu His Val Pro Glu 
1               5                   10                  15      


His Leu Ile Ala Asp Gly Ser Arg Phe Ile Leu Leu Glu Gly Ser Gln 
            20                  25                  30          


Leu Asp Ala Ser Asp Trp Leu Asn Pro Ala Gln Val Val Leu Phe Ser 
        35                  40                  45              


Gln Gln Asn Ser Ser Gly Pro Trp Ala Met Asp Leu Cys Ala Arg Arg 
    50                  55                  60                  


Leu Leu Asp Pro Cys Glu His Gln Cys Asp Pro Glu Thr Gly Glu Cys 
65                  70                  75                  80  


Leu Cys Tyr Glu Gly Tyr Met Lys Asp Pro Val His Lys His Leu Cys 
                85                  90                  95      


Ile Arg Asn Glu Trp Gly Thr Asn Gln Gly Pro Trp Pro Tyr Thr Ile 
            100                 105                 110         


Phe Gln Arg Gly Phe Asp Leu Val Leu Gly Glu Gln Pro Ser Asp Lys 
        115                 120                 125             


Ile Phe Arg Phe Thr Tyr Thr Leu Gly Glu Gly Met Trp Leu Pro Leu 
    130                 135                 140                 


Ser Lys Ser Phe Val Ile Pro Pro Ala Glu Leu Ala Ile Asn Pro Ser 
145                 150                 155                 160 


Ala Lys Cys Lys Thr Asp Met Thr Val Met Glu Asp Ala Val Glu Val 
                165                 170                 175     


Arg Glu Glu Leu Met Thr Ser Ser Ser Phe Asp Ser Leu Glu Val Leu 
            180                 185                 190         


Leu Asp Ser Phe Gly Pro Val Arg Asp Cys Ser Lys Asp Asn Gly Gly 
        195                 200                 205             


Cys Ser Lys Asn Phe Arg Cys Ile Ser Asp Arg Lys Leu Asp Ser Thr 
    210                 215                 220                 


Gly Cys Val Cys Pro Ser Gly Leu Ser Pro Met Lys Asp Ser Ser Gly 
225                 230                 235                 240 


Cys Tyr Asp Arg His Ile Gly Val Asp Cys Ser Asp Gly Phe Asn Gly 
                245                 250                 255     


Gly Cys Glu Gln Leu Cys Leu Gln Gln Met Ala Pro Phe Pro Asp Asp 
            260                 265                 270         


Pro Thr Leu Tyr Asn Ile Leu Met Phe Cys Gly Cys Ile Glu Asp Tyr 
        275                 280                 285             


Lys Leu Gly Val Asp Gly Arg Ser Cys Gln Leu Ile Thr Glu Thr Cys 
    290                 295                 300                 


Pro Glu Gly Ser Asp Cys Gly Glu Ser Arg Glu Leu Pro Met Asn Gln 
305                 310                 315                 320 


Thr Leu Phe Gly Glu Met Phe Phe Gly Tyr Asn Asn His Ser Lys Glu 
                325                 330                 335     


Val Ala Ala Gly Gln Val Leu Lys Gly Thr Phe Arg Gln Asn Asn Phe 
            340                 345                 350         


Ala Arg Gly Leu Asp Gln Gln Leu Pro Asp Gly Leu Val Val Ala Thr 
        355                 360                 365             


Val Pro Leu Glu Asn Gln Cys Leu Glu Glu Ile Ser Glu Pro Thr Pro 
    370                 375                 380                 


Asp Pro Asp Phe Leu Thr Gly Met Val Asn Phe Ser Glu Val Ser Gly 
385                 390                 395                 400 


Tyr Pro Val Leu Gln His Trp Lys Val Arg Ser Val Met Tyr His Ile 
                405                 410                 415     


Lys Leu Asn Gln Val Ala Ile Ser Gln Ala Leu Ser Asn Ala Leu His 
            420                 425                 430         


Ser Leu Asp Gly Ala Thr Ser Arg Ala Asp Phe Val Ala Leu Leu Asp 
        435                 440                 445             


Gln Phe Gly Asn His Tyr Ile Gln Glu Ala Ile Tyr Gly Phe Glu Glu 
    450                 455                 460                 


Ser Cys Ser Ile Trp Tyr Pro Asn Lys Gln Val Gln Arg Arg Leu Trp 
465                 470                 475                 480 


Leu Glu Tyr Glu Asp Ile Ser Lys Gly Asn Ser Pro Ser Asp Glu Ser 
                485                 490                 495     


Glu Glu Arg Glu Arg Asp Pro Lys Val Leu Thr Phe Pro Glu Tyr Ile 
            500                 505                 510         


Thr Ser Leu Ser Asp Ser Gly Thr Lys Arg Met Ala Ala Gly Val Arg 
        515                 520                 525             


Met Glu Cys Gln Ser Lys Gly Arg Cys Pro Ser Ser Cys Pro Leu Cys 
    530                 535                 540                 


His Val Thr Ser Ser Pro Asp Thr Pro Ala Glu Pro Val Leu Leu Glu 
545                 550                 555                 560 


Val Thr Lys Ala Ala Pro Ile Tyr Glu Leu Val Thr Asn Asn Gln Thr 
                565                 570                 575     


Gln Arg Leu Leu Gln Glu Ala Thr Met Ser Ser Leu Trp Cys Ser Gly 
            580                 585                 590         


Thr Gly Asp Val Ile Glu Asp Trp Cys Arg Cys Asp Ser Thr Ala Phe 
        595                 600                 605             


Gly Ala Asp Gly Leu Pro Thr Cys Ala Pro Leu Pro Gln Pro Val Leu 
    610                 615                 620                 


Arg Leu Ser Thr Val His Glu Pro Ser Ser Thr Leu Val Val Leu Glu 
625                 630                 635                 640 


Trp Glu His Ser Glu Pro Pro Ile Gly Val Gln Ile Val Asp Tyr Leu 
                645                 650                 655     


Leu Arg Gln Glu Lys Val Thr Asp Arg Met Asp His Ser Lys Val Glu 
            660                 665                 670         


Thr Glu Thr Val Leu Ser Phe Val Asp Asp Ile Ile Ser Gly Ala Lys 
        675                 680                 685             


Ser Pro Cys Ala Met Pro Ser Gln Val Pro Asp Lys Gln Leu Thr Thr 
    690                 695                 700                 


Ile Ser Leu Ile Ile Arg Cys Leu Glu Pro Asp Thr Ile Tyr Met Phe 
705                 710                 715                 720 


Thr Leu Trp Gly Val Asp Asn Thr Gly Arg Arg Ser Arg Pro Ser Asp 
                725                 730                 735     


Val Ile Val Lys Thr Pro Cys Pro Val Val Asp Asp Val Lys Ala Gln 
            740                 745                 750         


Glu Ile Ala Asp Lys Ile Tyr Asn Leu Phe Asn Gly Tyr Thr Ser Gly 
        755                 760                 765             


Lys Glu Gln Gln Thr Ala Tyr Asn Thr Leu Leu Asp Leu Gly Ser Pro 
    770                 775                 780                 


Thr Leu His Arg Val Leu Tyr His Tyr Asn Gln His Tyr Glu Ser Phe 
785                 790                 795                 800 


Gly Glu Phe Thr Trp Arg Cys Glu Asp Glu Leu Gly Pro Arg 
                805                 810                 


<210>  52
<211>  157
<212>  PRT
<213>  Homo Sapiens

<400>  52

Gly Ala Thr Ala Ala Ala Ser Arg Glu Pro Asp Ser Pro Cys Arg Leu 
1               5                   10                  15      


Lys Thr Val Thr Val Ser Thr Leu Pro Ala Leu Arg Glu Ser Asp Ile 
            20                  25                  30          


Gly Trp Ser Gly Ala Arg Ala Gly Ala Gly Ala Gly Thr Gly Ala Gly 
        35                  40                  45              


Ala Ala Ala Ala Ala Ala Ser Pro Gly Ser Pro Gly Ser Ala Gly Thr 
    50                  55                  60                  


Ala Ala Glu Ser Arg Leu Leu Leu Phe Val Arg Asn Glu Leu Pro Gly 
65                  70                  75                  80  


Arg Ile Ala Val Gln Asp Asp Leu Asp Asn Thr Glu Leu Pro Phe Phe 
                85                  90                  95      


Thr Leu Glu Met Ser Gly Thr Ala Ala Asp Ile Ser Leu Val His Trp 
            100                 105                 110         


Arg Gln Gln Trp Leu Glu Asn Gly Thr Leu Tyr Phe His Val Ser Met 
        115                 120                 125             


Ser Ser Ser Gly Gln Leu Ala Gln Ala Thr Ala Pro Thr Leu Gln Glu 
    130                 135                 140                 


Pro Ser Glu Ile Val Glu Glu Gln Met His Ile Leu His 
145                 150                 155         


<210>  53
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  53

Leu Pro Glu Ile Cys Thr Gln Cys Pro Gly Ser Val Gln Asn Leu Ser 
1               5                   10                  15      


Lys Val Ala Phe Tyr Cys Lys Thr Thr Arg Glu Leu Met Leu His Ala 
            20                  25                  30          


Arg Cys Cys Leu Asn Gln Lys Gly Thr Ile Leu Gly Leu Asp Leu Gln 
        35                  40                  45              


Asn Cys Ser Leu Glu Asp Pro Gly Pro Asn Phe His Gln Ala His Thr 
    50                  55                  60                  


Thr Val Ile Ile Asp Leu Gln Ala Asn Pro Leu Lys Gly Asp Leu Ala 
65                  70                  75                  80  


Asn Thr Phe Arg Gly Phe Thr Gln Leu Gln Thr Leu Ile Leu Pro Gln 
                85                  90                  95      


His Val Asn Cys Pro Gly Gly Ile Asn Ala Trp Asn Thr Ile Thr Ser 
            100                 105                 110         


Tyr Ile Asp Asn Gln Ile Cys Gln Gly Gln Lys Asn Leu Cys Asn Asn 
        115                 120                 125             


Thr Gly Asp Pro Glu Met Cys Pro Glu Asn Gly Ser Cys Val Pro Asp 
    130                 135                 140                 


Gly Pro Gly Leu Leu Gln Cys Val Cys Ala Asp Gly Phe His Gly Tyr 
145                 150                 155                 160 


Lys Cys Met Arg Gln Gly Ser Phe Ser 
                165                 


<210>  54
<211>  1189
<212>  PRT
<213>  Homo Sapiens

<400>  54

Ala Ala Ala Ala Ala Ala Val Ser Gly Ser Ala Ala Ala Glu Ala Lys 
1               5                   10                  15      


Glu Cys Asp Arg Pro Cys Val Asn Gly Gly Arg Cys Asn Pro Gly Thr 
            20                  25                  30          


Gly Gln Cys Val Cys Pro Ala Gly Trp Val Gly Glu Gln Cys Gln His 
        35                  40                  45              


Cys Gly Gly Arg Phe Arg Leu Thr Gly Ser Ser Gly Phe Val Thr Asp 
    50                  55                  60                  


Gly Pro Gly Asn Tyr Lys Tyr Lys Thr Lys Cys Thr Trp Leu Ile Glu 
65                  70                  75                  80  


Gly Gln Pro Asn Arg Ile Met Arg Leu Arg Phe Asn His Phe Ala Thr 
                85                  90                  95      


Glu Cys Ser Trp Asp His Leu Tyr Val Tyr Asp Gly Asp Ser Ile Tyr 
            100                 105                 110         


Ala Pro Leu Val Ala Ala Phe Ser Gly Leu Ile Val Pro Glu Arg Asp 
        115                 120                 125             


Gly Asn Glu Thr Val Pro Glu Val Val Ala Thr Ser Gly Tyr Ala Leu 
    130                 135                 140                 


Leu His Phe Phe Ser Asp Ala Ala Tyr Asn Leu Thr Gly Phe Asn Ile 
145                 150                 155                 160 


Thr Tyr Ser Phe Asp Met Cys Pro Asn Asn Cys Ser Gly Arg Gly Glu 
                165                 170                 175     


Cys Lys Ile Ser Asn Ser Ser Asp Thr Val Glu Cys Glu Cys Ser Glu 
            180                 185                 190         


Asn Trp Lys Gly Glu Ala Cys Asp Ile Pro His Cys Thr Asp Asn Cys 
        195                 200                 205             


Gly Phe Pro His Arg Gly Ile Cys Asn Ser Ser Asp Val Arg Gly Cys 
    210                 215                 220                 


Ser Cys Phe Ser Asp Trp Gln Gly Pro Gly Cys Ser Val Pro Val Pro 
225                 230                 235                 240 


Ala Asn Gln Ser Phe Trp Thr Arg Glu Glu Tyr Ser Asn Leu Lys Leu 
                245                 250                 255     


Pro Arg Ala Ser His Lys Ala Val Val Asn Gly Asn Ile Met Trp Val 
            260                 265                 270         


Val Gly Gly Tyr Met Phe Asn His Ser Asp Tyr Asn Met Val Leu Ala 
        275                 280                 285             


Tyr Asp Leu Ala Ser Arg Glu Trp Leu Pro Leu Asn Arg Ser Val Asn 
    290                 295                 300                 


Asn Val Val Val Arg Tyr Gly His Ser Leu Ala Leu Tyr Lys Asp Lys 
305                 310                 315                 320 


Ile Tyr Met Tyr Gly Gly Lys Ile Asp Ser Thr Gly Asn Val Thr Asn 
                325                 330                 335     


Glu Leu Arg Val Phe His Ile His Asn Glu Ser Trp Val Leu Leu Thr 
            340                 345                 350         


Pro Lys Ala Lys Glu Gln Tyr Ala Val Val Gly His Ser Ala His Ile 
        355                 360                 365             


Val Thr Leu Lys Asn Gly Arg Val Val Met Leu Val Ile Phe Gly His 
    370                 375                 380                 


Cys Pro Leu Tyr Gly Tyr Ile Ser Asn Val Gln Glu Tyr Asp Leu Asp 
385                 390                 395                 400 


Lys Asn Thr Trp Ser Ile Leu His Thr Gln Gly Ala Leu Val Gln Gly 
                405                 410                 415     


Gly Tyr Gly His Ser Ser Val Tyr Asp His Arg Thr Arg Ala Leu Tyr 
            420                 425                 430         


Val His Gly Gly Tyr Lys Ala Phe Ser Ala Asn Lys Tyr Arg Leu Ala 
        435                 440                 445             


Asp Asp Leu Tyr Arg Tyr Asp Val Asp Thr Gln Met Trp Thr Ile Leu 
    450                 455                 460                 


Lys Asp Ser Arg Phe Phe Arg Tyr Leu His Thr Ala Val Ile Val Ser 
465                 470                 475                 480 


Gly Thr Met Leu Val Phe Gly Gly Asn Thr His Asn Asp Thr Ser Met 
                485                 490                 495     


Ser His Gly Ala Lys Cys Phe Ser Ser Asp Phe Met Ala Tyr Asp Ile 
            500                 505                 510         


Ala Cys Asp Arg Trp Ser Val Leu Pro Arg Pro Asp Leu His His Asp 
        515                 520                 525             


Val Asn Arg Phe Gly His Ser Ala Val Leu His Asn Ser Thr Met Tyr 
    530                 535                 540                 


Val Phe Gly Gly Phe Asn Ser Leu Leu Leu Ser Asp Ile Leu Val Phe 
545                 550                 555                 560 


Thr Ser Glu Gln Cys Asp Ala His Arg Ser Glu Ala Ala Cys Leu Ala 
                565                 570                 575     


Ala Gly Pro Gly Ile Arg Cys Val Trp Asn Thr Gly Ser Ser Gln Cys 
            580                 585                 590         


Ile Ser Trp Ala Leu Ala Thr Asp Glu Gln Glu Glu Lys Leu Lys Ser 
        595                 600                 605             


Glu Cys Phe Ser Lys Arg Thr Leu Asp His Asp Arg Cys Asp Gln His 
    610                 615                 620                 


Thr Asp Cys Tyr Ser Cys Thr Ala Asn Thr Asn Asp Cys His Trp Cys 
625                 630                 635                 640 


Asn Asp His Cys Val Pro Arg Asn His Ser Cys Ser Glu Gly Gln Ile 
                645                 650                 655     


Ser Ile Phe Arg Tyr Glu Asn Cys Pro Lys Asp Asn Pro Met Tyr Tyr 
            660                 665                 670         


Cys Asn Lys Lys Thr Ser Cys Arg Ser Cys Ala Leu Asp Gln Asn Cys 
        675                 680                 685             


Gln Trp Glu Pro Arg Asn Gln Glu Cys Ile Ala Leu Pro Glu Asn Ile 
    690                 695                 700                 


Cys Gly Ile Gly Trp His Leu Val Gly Asn Ser Cys Leu Lys Ile Thr 
705                 710                 715                 720 


Thr Ala Lys Glu Asn Tyr Asp Asn Ala Lys Leu Phe Cys Arg Asn His 
                725                 730                 735     


Asn Ala Leu Leu Ala Ser Leu Thr Thr Gln Lys Lys Val Glu Phe Val 
            740                 745                 750         


Leu Lys Gln Leu Arg Ile Met Gln Ser Ser Gln Ser Met Ser Lys Leu 
        755                 760                 765             


Thr Leu Thr Pro Trp Val Gly Leu Arg Lys Ile Asn Val Ser Tyr Trp 
    770                 775                 780                 


Cys Trp Glu Asp Met Ser Pro Phe Thr Asn Ser Leu Leu Gln Trp Met 
785                 790                 795                 800 


Pro Ser Glu Pro Ser Asp Ala Gly Phe Cys Gly Ile Leu Ser Glu Pro 
                805                 810                 815     


Ser Thr Arg Gly Leu Lys Ala Ala Thr Cys Ile Asn Pro Leu Asn Gly 
            820                 825                 830         


Ser Val Cys Glu Arg Pro Ala Asn His Ser Ala Lys Gln Cys Arg Thr 
        835                 840                 845             


Pro Cys Ala Leu Arg Thr Ala Cys Gly Asp Cys Thr Ser Gly Ser Ser 
    850                 855                 860                 


Glu Cys Met Trp Cys Ser Asn Met Lys Gln Cys Val Asp Ser Asn Ala 
865                 870                 875                 880 


Tyr Val Ala Ser Phe Pro Phe Gly Gln Cys Met Glu Trp Tyr Thr Met 
                885                 890                 895     


Ser Thr Cys Pro Pro Glu Asn Cys Ser Gly Tyr Cys Thr Cys Ser His 
            900                 905                 910         


Cys Leu Glu Gln Pro Gly Cys Gly Trp Cys Thr Asp Pro Ser Asn Thr 
        915                 920                 925             


Gly Lys Gly Lys Cys Ile Glu Gly Ser Tyr Lys Gly Pro Val Lys Met 
    930                 935                 940                 


Pro Ser Gln Ala Pro Thr Gly Asn Phe Tyr Pro Gln Pro Leu Leu Asn 
945                 950                 955                 960 


Ser Ser Met Cys Leu Glu Asp Ser Arg Tyr Asn Trp Ser Phe Ile His 
                965                 970                 975     


Cys Pro Ala Cys Gln Cys Asn Gly His Ser Lys Cys Ile Asn Gln Ser 
            980                 985                 990         


Ile Cys Glu Lys Cys Glu Asn Leu  Thr Thr Gly Lys His  Cys Glu Thr 
        995                 1000                 1005             


Cys Ile  Ser Gly Phe Tyr Gly  Asp Pro Thr Asn Gly  Gly Lys Cys 
    1010                 1015                 1020             


Gln Pro  Cys Lys Cys Asn Gly  His Ala Ser Leu Cys  Asn Thr Asn 
    1025                 1030                 1035             


Thr Gly  Lys Cys Phe Cys Thr  Thr Lys Gly Val Lys  Gly Asp Glu 
    1040                 1045                 1050             


Cys Gln  Leu Cys Glu Val Glu  Asn Arg Tyr Gln Gly  Asn Pro Leu 
    1055                 1060                 1065             


Arg Gly  Thr Cys Tyr Tyr Thr  Leu Leu Ile Asp Tyr  Gln Phe Thr 
    1070                 1075                 1080             


Phe Ser  Leu Ser Gln Glu Asp  Asp Arg Tyr Tyr Thr  Ala Ile Asn 
    1085                 1090                 1095             


Phe Val  Ala Thr Pro Asp Glu  Gln Asn Arg Asp Leu  Asp Met Phe 
    1100                 1105                 1110             


Ile Asn  Ala Ser Lys Asn Phe  Asn Leu Asn Ile Thr  Trp Ala Ala 
    1115                 1120                 1125             


Ser Phe  Ser Ala Gly Thr Gln  Ala Gly Glu Glu Met  Pro Val Val 
    1130                 1135                 1140             


Ser Lys  Thr Asn Ile Lys Glu  Tyr Lys Asp Ser Phe  Ser Asn Glu 
    1145                 1150                 1155             


Lys Phe  Asp Phe Arg Asn His  Pro Asn Ile Thr Phe  Phe Val Tyr 
    1160                 1165                 1170             


Val Ser  Asn Phe Thr Trp Pro  Ile Lys Ile Gln Val  Gln Thr Glu 
    1175                 1180                 1185             


Gln 
    


<210>  55
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  55

Leu Tyr Ala Gln Val Ser Gln Ser Lys Pro Cys Glu Arg Thr Gly Ser 
1               5                   10                  15      


Cys Phe Ser Gly Arg Cys Val Asn Ser Thr Cys Leu Cys Asp Pro Gly 
            20                  25                  30          


Trp Val Gly Asp Gln Cys Gln His Cys Gln Gly Arg Phe Lys Leu Thr 
        35                  40                  45              


Glu Pro Ser Gly Tyr Leu Thr Asp Gly Pro Ile Asn Tyr Lys Tyr Lys 
    50                  55                  60                  


Thr Lys Cys Thr Trp Leu Ile Glu Gly Tyr Pro Asn Ala Val Leu Arg 
65                  70                  75                  80  


Leu Arg Phe Asn His Phe Ala Thr Glu Cys Ser Trp Asp His Met Tyr 
                85                  90                  95      


Val Tyr Asp Gly Asp Ser Ile Tyr Ala Pro Leu Ile Ala Val Leu Ser 
            100                 105                 110         


Gly Leu Ile Val Pro Glu Ile Arg Gly Asn Glu Thr Val Pro Glu Val 
        115                 120                 125             


Val Thr Thr Ser Gly Tyr Ala Leu Leu His Phe Phe Ser Asp Ala Ala 
    130                 135                 140                 


Tyr Asn Leu Thr Gly Phe Asn Ile Phe Tyr Ser Ile Asn Ser Cys Pro 
145                 150                 155                 160 


Asn Asn Cys Ser Gly His Gly Lys Cys Thr Thr Ser Val Ser Val Pro 
                165                 170                 175     


Ser Gln Val Tyr Cys Glu Cys Asp Lys Tyr Trp Lys Gly Glu Ala Cys 
            180                 185                 190         


Asp Ile Pro Tyr Cys Lys Ala Asn Cys Gly Ser Pro Asp His Gly Tyr 
        195                 200                 205             


Cys Asp Leu Thr Gly Glu Lys Leu Cys Val Cys Asn Asp Ser Trp Gln 
    210                 215                 220                 


Gly Pro Asp Cys Ser Leu Asn Val Pro Ser Thr Glu Ser Tyr Trp Ile 
225                 230                 235                 240 


Leu Pro Asn Val Lys Pro Phe Ser Pro Ser Val Gly Arg Ala Ser His 
                245                 250                 255     


Lys Ala Val Leu His Gly Lys Phe Met Trp Val Ile Gly Gly Tyr Thr 
            260                 265                 270         


Phe Asn Tyr Ser Ser Phe Gln Met Val Leu Asn Tyr Asn Leu Glu Ser 
        275                 280                 285             


Ser Ile Trp Asn Val Gly Thr Pro Ser Arg Gly Pro Leu Gln Arg Tyr 
    290                 295                 300                 


Gly His Ser Leu Ala Leu Tyr Gln Glu Asn Ile Phe Met Tyr Gly Gly 
305                 310                 315                 320 


Arg Ile Glu Thr Asn Asp Gly Asn Val Thr Asp Glu Leu Trp Val Phe 
                325                 330                 335     


Asn Ile His Ser Gln Ser Trp Ser Thr Lys Thr Pro Thr Val Leu Gly 
            340                 345                 350         


His Gly Gln Gln Tyr Ala Val Glu Gly His Ser Ala His Ile Met Glu 
        355                 360                 365             


Leu Asp Ser Arg Asp Val Val Met Ile Ile Ile Phe Gly Tyr Ser Ala 
    370                 375                 380                 


Ile Tyr Gly Tyr Thr Ser Ser Ile Gln Glu Tyr His Ile Cys Glu Leu 
385                 390                 395                 400 


Leu Lys Asn Cys Asn Phe Phe Ile Asp Trp Glu Cys Phe Ser Leu 
                405                 410                 415 


<210>  56
<211>  426
<212>  PRT
<213>  Homo Sapiens

<400>  56

Ala Pro Arg Gly Thr Gln Ala Glu Glu Ser Pro Phe Val Gly Asn Pro 
1               5                   10                  15      


Gly Asn Ile Thr Gly Ala Arg Gly Leu Thr Gly Thr Leu Arg Cys Gln 
            20                  25                  30          


Leu Gln Val Gln Gly Glu Pro Pro Glu Val His Trp Leu Arg Asp Gly 
        35                  40                  45              


Gln Ile Leu Glu Leu Ala Asp Ser Thr Gln Thr Gln Val Pro Leu Gly 
    50                  55                  60                  


Glu Asp Glu Gln Asp Asp Trp Ile Val Val Ser Gln Leu Arg Ile Thr 
65                  70                  75                  80  


Ser Leu Gln Leu Ser Asp Thr Gly Gln Tyr Gln Cys Leu Val Phe Leu 
                85                  90                  95      


Gly His Gln Thr Phe Val Ser Gln Pro Gly Tyr Val Gly Leu Glu Gly 
            100                 105                 110         


Leu Pro Tyr Phe Leu Glu Glu Pro Glu Asp Arg Thr Val Ala Ala Asn 
        115                 120                 125             


Thr Pro Phe Asn Leu Ser Cys Gln Ala Gln Gly Pro Pro Glu Pro Val 
    130                 135                 140                 


Asp Leu Leu Trp Leu Gln Asp Ala Val Pro Leu Ala Thr Ala Pro Gly 
145                 150                 155                 160 


His Gly Pro Gln Arg Ser Leu His Val Pro Gly Leu Asn Lys Thr Ser 
                165                 170                 175     


Ser Phe Ser Cys Glu Ala His Asn Ala Lys Gly Val Thr Thr Ser Arg 
            180                 185                 190         


Thr Ala Thr Ile Thr Val Leu Pro Gln Gln Pro Arg Asn Leu His Leu 
        195                 200                 205             


Val Ser Arg Gln Pro Thr Glu Leu Glu Val Ala Trp Thr Pro Gly Leu 
    210                 215                 220                 


Ser Gly Ile Tyr Pro Leu Thr His Cys Thr Leu Gln Ala Val Leu Ser 
225                 230                 235                 240 


Asp Asp Gly Met Gly Ile Gln Ala Gly Glu Pro Asp Pro Pro Glu Glu 
                245                 250                 255     


Pro Leu Thr Ser Gln Ala Ser Val Pro Pro His Gln Leu Arg Leu Gly 
            260                 265                 270         


Ser Leu His Pro His Thr Pro Tyr His Ile Arg Val Ala Cys Thr Ser 
        275                 280                 285             


Ser Gln Gly Pro Ser Ser Trp Thr His Trp Leu Pro Val Glu Thr Pro 
    290                 295                 300                 


Glu Gly Val Pro Leu Gly Pro Pro Glu Asn Ile Ser Ala Thr Arg Asn 
305                 310                 315                 320 


Gly Ser Gln Ala Phe Val His Trp Gln Glu Pro Arg Ala Pro Leu Gln 
                325                 330                 335     


Gly Thr Leu Leu Gly Tyr Arg Leu Ala Tyr Gln Gly Gln Asp Thr Pro 
            340                 345                 350         


Glu Val Leu Met Asp Ile Gly Leu Arg Gln Glu Val Thr Leu Glu Leu 
        355                 360                 365             


Gln Gly Asp Gly Ser Val Ser Asn Leu Thr Val Cys Val Ala Ala Tyr 
    370                 375                 380                 


Thr Ala Ala Gly Asp Gly Pro Trp Ser Leu Pro Val Pro Leu Glu Ala 
385                 390                 395                 400 


Trp Arg Pro Gly Gln Ala Gln Pro Val His Gln Leu Val Lys Glu Pro 
                405                 410                 415     


Ser Thr Pro Ala Phe Ser Trp Pro Trp Trp 
            420                 425     


<210>  57
<211>  278
<212>  PRT
<213>  Homo Sapiens

<400>  57

Gln Glu Asn Gln Asp Gly Arg Tyr Ser Leu Thr Tyr Ile Tyr Thr Gly 
1               5                   10                  15      


Leu Ser Lys His Val Glu Asp Val Pro Ala Phe Gln Ala Leu Gly Ser 
            20                  25                  30          


Leu Asn Asp Leu Gln Phe Phe Arg Tyr Asn Ser Lys Asp Arg Lys Ser 
        35                  40                  45              


Gln Pro Met Gly Leu Trp Arg Gln Val Glu Gly Met Glu Asp Trp Lys 
    50                  55                  60                  


Gln Asp Ser Gln Leu Gln Lys Ala Arg Glu Asp Ile Phe Met Glu Thr 
65                  70                  75                  80  


Leu Lys Asp Ile Val Glu Tyr Tyr Asn Asp Ser Asn Gly Ser His Val 
                85                  90                  95      


Leu Gln Gly Arg Phe Gly Cys Glu Ile Glu Asn Asn Arg Ser Ser Gly 
            100                 105                 110         


Ala Phe Trp Lys Tyr Tyr Tyr Asp Gly Lys Asp Tyr Ile Glu Phe Asn 
        115                 120                 125             


Lys Glu Ile Pro Ala Trp Val Pro Phe Asp Pro Ala Ala Gln Ile Thr 
    130                 135                 140                 


Lys Gln Lys Trp Glu Ala Glu Pro Val Tyr Val Gln Arg Ala Lys Ala 
145                 150                 155                 160 


Tyr Leu Glu Glu Glu Cys Pro Ala Thr Leu Arg Lys Tyr Leu Lys Tyr 
                165                 170                 175     


Ser Lys Asn Ile Leu Asp Arg Gln Asp Pro Pro Ser Val Val Val Thr 
            180                 185                 190         


Ser His Gln Ala Pro Gly Glu Lys Lys Lys Leu Lys Cys Leu Ala Tyr 
        195                 200                 205             


Asp Phe Tyr Pro Gly Lys Ile Asp Val His Trp Thr Arg Ala Gly Glu 
    210                 215                 220                 


Val Gln Glu Pro Glu Leu Arg Gly Asp Val Leu His Asn Gly Asn Gly 
225                 230                 235                 240 


Thr Tyr Gln Ser Trp Val Val Val Ala Val Pro Pro Gln Asp Thr Ala 
                245                 250                 255     


Pro Tyr Ser Cys His Val Gln His Ser Ser Leu Ala Gln Pro Leu Val 
            260                 265                 270         


Val Pro Trp Glu Ala Ser 
        275             


<210>  58
<211>  99
<212>  PRT
<213>  Homo Sapiens

<400>  58

Ile Gln Arg Thr Pro Lys Ile Gln Val Tyr Ser Arg His Pro Ala Glu 
1               5                   10                  15      


Asn Gly Lys Ser Asn Phe Leu Asn Cys Tyr Val Ser Gly Phe His Pro 
            20                  25                  30          


Ser Asp Ile Glu Val Asp Leu Leu Lys Asn Gly Glu Arg Ile Glu Lys 
        35                  40                  45              


Val Glu His Ser Asp Leu Ser Phe Ser Lys Asp Trp Ser Phe Tyr Leu 
    50                  55                  60                  


Leu Tyr Tyr Thr Glu Phe Thr Pro Thr Glu Lys Asp Glu Tyr Ala Cys 
65                  70                  75                  80  


Arg Val Asn His Val Thr Leu Ser Gln Pro Lys Ile Val Lys Trp Asp 
                85                  90                  95      


Arg Asp Met 
            


<210>  59
<211>  516
<212>  PRT
<213>  Homo Sapiens

<400>  59

Glu Val Arg Leu Ser Val Pro Pro Leu Val Glu Val Met Arg Gly Lys 
1               5                   10                  15      


Ser Val Ile Leu Asp Cys Thr Pro Thr Gly Thr His Asp His Tyr Met 
            20                  25                  30          


Leu Glu Trp Phe Leu Thr Asp Arg Ser Gly Ala Arg Pro Arg Leu Ala 
        35                  40                  45              


Ser Ala Glu Met Gln Gly Ser Glu Leu Gln Val Thr Met His Asp Thr 
    50                  55                  60                  


Arg Gly Arg Ser Pro Pro Tyr Gln Leu Asp Ser Gln Gly Arg Leu Val 
65                  70                  75                  80  


Leu Ala Glu Ala Gln Val Gly Asp Glu Arg Asp Tyr Val Cys Val Val 
                85                  90                  95      


Arg Ala Gly Ala Ala Gly Thr Ala Glu Ala Thr Ala Arg Leu Asn Val 
            100                 105                 110         


Phe Ala Lys Pro Glu Ala Thr Glu Val Ser Pro Asn Lys Gly Thr Leu 
        115                 120                 125             


Ser Val Met Glu Asp Ser Ala Gln Glu Ile Ala Thr Cys Asn Ser Arg 
    130                 135                 140                 


Asn Gly Asn Pro Ala Pro Lys Ile Thr Trp Tyr Arg Asn Gly Gln Arg 
145                 150                 155                 160 


Leu Glu Val Pro Val Glu Met Asn Pro Glu Gly Tyr Met Thr Ser Arg 
                165                 170                 175     


Thr Val Arg Glu Ala Ser Gly Leu Leu Ser Leu Thr Ser Thr Leu Tyr 
            180                 185                 190         


Leu Arg Leu Arg Lys Asp Asp Arg Asp Ala Ser Phe His Cys Ala Ala 
        195                 200                 205             


His Tyr Ser Leu Pro Glu Gly Arg His Gly Arg Leu Asp Ser Pro Thr 
    210                 215                 220                 


Phe His Leu Thr Leu His Tyr Pro Thr Glu His Val Gln Phe Trp Val 
225                 230                 235                 240 


Gly Ser Pro Ser Thr Pro Ala Gly Trp Val Arg Glu Gly Asp Thr Val 
                245                 250                 255     


Gln Leu Leu Cys Arg Gly Asp Gly Ser Pro Ser Pro Glu Tyr Thr Leu 
            260                 265                 270         


Phe Arg Leu Gln Asp Glu Gln Glu Glu Val Leu Asn Val Asn Leu Glu 
        275                 280                 285             


Gly Asn Leu Thr Leu Glu Gly Val Thr Arg Gly Gln Ser Gly Thr Tyr 
    290                 295                 300                 


Gly Cys Arg Val Glu Asp Tyr Asp Ala Ala Asp Asp Val Gln Leu Ser 
305                 310                 315                 320 


Lys Thr Leu Glu Leu Arg Val Ala Tyr Leu Asp Pro Leu Glu Leu Ser 
                325                 330                 335     


Glu Gly Lys Val Leu Ser Leu Pro Leu Asn Ser Ser Ala Val Val Asn 
            340                 345                 350         


Cys Ser Val His Gly Leu Pro Thr Pro Ala Leu Arg Trp Thr Lys Asp 
        355                 360                 365             


Ser Thr Pro Leu Gly Asp Gly Pro Met Leu Ser Leu Ser Ser Ile Thr 
    370                 375                 380                 


Phe Asp Ser Asn Gly Thr Tyr Val Cys Glu Ala Ser Leu Pro Thr Val 
385                 390                 395                 400 


Pro Val Leu Ser Arg Thr Gln Asn Phe Thr Leu Leu Val Gln Gly Ser 
                405                 410                 415     


Pro Glu Leu Lys Thr Ala Glu Ile Glu Pro Lys Ala Asp Gly Ser Trp 
            420                 425                 430         


Arg Glu Gly Asp Glu Val Thr Leu Ile Cys Ser Ala Arg Gly His Pro 
        435                 440                 445             


Asp Pro Lys Leu Ser Trp Ser Gln Leu Gly Gly Ser Pro Ala Glu Pro 
    450                 455                 460                 


Ile Pro Gly Arg Gln Gly Trp Val Ser Ser Ser Leu Thr Leu Lys Val 
465                 470                 475                 480 


Thr Ser Ala Leu Ser Arg Asp Gly Ile Ser Cys Glu Ala Ser Asn Pro 
                485                 490                 495     


His Gly Asn Lys Arg His Val Phe His Phe Gly Thr Val Ser Pro Gln 
            500                 505                 510         


Thr Ser Gln Ala 
        515     


<210>  60
<211>  889
<212>  PRT
<213>  Homo Sapiens

<400>  60

Asp Val Leu Glu Gly Asp Ser Ser Glu Asp Arg Ala Phe Arg Val Arg 
1               5                   10                  15      


Ile Ala Gly Asp Ala Pro Leu Gln Gly Val Leu Gly Gly Ala Leu Thr 
            20                  25                  30          


Ile Pro Cys His Val His Tyr Leu Arg Pro Pro Pro Ser Arg Arg Ala 
        35                  40                  45              


Val Leu Gly Ser Pro Arg Val Lys Trp Thr Phe Leu Ser Arg Gly Arg 
    50                  55                  60                  


Glu Ala Glu Val Leu Val Ala Arg Gly Val Arg Val Lys Val Asn Glu 
65                  70                  75                  80  


Ala Tyr Arg Phe Arg Val Ala Leu Pro Ala Tyr Pro Ala Ser Leu Thr 
                85                  90                  95      


Asp Val Ser Leu Ala Leu Ser Glu Leu Arg Pro Asn Asp Ser Gly Ile 
            100                 105                 110         


Tyr Arg Cys Glu Val Gln His Gly Ile Asp Asp Ser Ser Asp Ala Val 
        115                 120                 125             


Glu Val Lys Val Lys Gly Val Val Phe Leu Tyr Arg Glu Gly Ser Ala 
    130                 135                 140                 


Arg Tyr Ala Phe Ser Phe Ser Gly Ala Gln Glu Ala Cys Ala Arg Ile 
145                 150                 155                 160 


Gly Ala His Ile Ala Thr Pro Glu Gln Leu Tyr Ala Ala Tyr Leu Gly 
                165                 170                 175     


Gly Tyr Glu Gln Cys Asp Ala Gly Trp Leu Ser Asp Gln Thr Val Arg 
            180                 185                 190         


Tyr Pro Ile Gln Thr Pro Arg Glu Ala Cys Tyr Gly Asp Met Asp Gly 
        195                 200                 205             


Phe Pro Gly Val Arg Asn Tyr Gly Val Val Asp Pro Asp Asp Leu Tyr 
    210                 215                 220                 


Asp Val Tyr Cys Tyr Ala Glu Asp Leu Asn Gly Glu Leu Phe Leu Gly 
225                 230                 235                 240 


Asp Pro Pro Glu Lys Leu Thr Leu Glu Glu Ala Arg Ala Tyr Cys Gln 
                245                 250                 255     


Glu Arg Gly Ala Glu Ile Ala Thr Thr Gly Gln Leu Tyr Ala Ala Trp 
            260                 265                 270         


Asp Gly Gly Leu Asp His Cys Ser Pro Gly Trp Leu Ala Asp Gly Ser 
        275                 280                 285             


Val Arg Tyr Pro Ile Val Thr Pro Ser Gln Arg Cys Gly Gly Gly Leu 
    290                 295                 300                 


Pro Gly Val Lys Thr Leu Phe Leu Phe Pro Asn Gln Thr Gly Phe Pro 
305                 310                 315                 320 


Asn Lys His Ser Arg Phe Asn Val Tyr Cys Phe Arg Asp Ser Ala Gln 
                325                 330                 335     


Pro Ser Ala Ile Pro Glu Ala Ser Asn Pro Ala Ser Asn Pro Ala Ser 
            340                 345                 350         


Asp Gly Leu Glu Ala Ile Val Thr Val Thr Glu Thr Leu Glu Glu Leu 
        355                 360                 365             


Gln Leu Pro Gln Glu Ala Thr Glu Ser Glu Ser Arg Gly Ala Ile Tyr 
    370                 375                 380                 


Ser Ile Pro Ile Met Glu Asp Gly Gly Gly Gly Ser Ser Thr Pro Glu 
385                 390                 395                 400 


Asp Pro Ala Glu Ala Pro Arg Thr Leu Leu Glu Phe Glu Thr Gln Ser 
                405                 410                 415     


Met Val Pro Pro Thr Gly Phe Ser Glu Glu Glu Gly Lys Ala Leu Glu 
            420                 425                 430         


Glu Glu Glu Lys Tyr Glu Asp Glu Glu Glu Lys Glu Glu Glu Glu Glu 
        435                 440                 445             


Glu Glu Glu Val Glu Asp Glu Ala Leu Trp Ala Trp Pro Ser Glu Leu 
    450                 455                 460                 


Ser Ser Pro Gly Pro Glu Ala Ser Leu Pro Thr Glu Pro Ala Ala Gln 
465                 470                 475                 480 


Glu Lys Ser Leu Ser Gln Ala Pro Ala Arg Ala Val Leu Gln Pro Gly 
                485                 490                 495     


Ala Ser Pro Leu Pro Asp Gly Glu Ser Glu Ala Ser Arg Pro Pro Arg 
            500                 505                 510         


Val His Gly Pro Pro Thr Glu Thr Leu Pro Thr Pro Arg Glu Arg Asn 
        515                 520                 525             


Leu Ala Ser Pro Ser Pro Ser Thr Leu Val Glu Ala Arg Glu Val Gly 
    530                 535                 540                 


Glu Ala Thr Gly Gly Pro Glu Leu Ser Gly Val Pro Arg Gly Glu Ser 
545                 550                 555                 560 


Glu Glu Thr Gly Ser Ser Glu Gly Ala Pro Ser Leu Leu Pro Ala Thr 
                565                 570                 575     


Arg Ala Pro Glu Gly Thr Arg Glu Leu Glu Ala Pro Ser Glu Asp Asn 
            580                 585                 590         


Ser Gly Arg Thr Ala Pro Ala Gly Thr Ser Val Gln Ala Gln Pro Val 
        595                 600                 605             


Leu Pro Thr Asp Ser Ala Ser Arg Gly Gly Val Ala Val Val Pro Ala 
    610                 615                 620                 


Ser Gly Asp Cys Val Pro Ser Pro Cys His Asn Gly Gly Thr Cys Leu 
625                 630                 635                 640 


Glu Glu Glu Glu Gly Val Arg Cys Leu Cys Leu Pro Gly Tyr Gly Gly 
                645                 650                 655     


Asp Leu Cys Asp Val Gly Leu Arg Phe Cys Asn Pro Gly Trp Asp Ala 
            660                 665                 670         


Phe Gln Gly Ala Cys Tyr Lys His Phe Ser Thr Arg Arg Ser Trp Glu 
        675                 680                 685             


Glu Ala Glu Thr Gln Cys Arg Met Tyr Gly Ala His Leu Ala Ser Ile 
    690                 695                 700                 


Ser Thr Pro Glu Glu Gln Asp Phe Ile Asn Asn Arg Tyr Arg Glu Tyr 
705                 710                 715                 720 


Gln Trp Ile Gly Leu Asn Asp Arg Thr Ile Glu Gly Asp Phe Leu Trp 
                725                 730                 735     


Ser Asp Gly Val Pro Leu Leu Tyr Glu Asn Trp Asn Pro Gly Gln Pro 
            740                 745                 750         


Asp Ser Tyr Phe Leu Ser Gly Glu Asn Cys Val Val Met Val Trp His 
        755                 760                 765             


Asp Gln Gly Gln Trp Ser Asp Val Pro Cys Asn Tyr His Leu Ser Tyr 
    770                 775                 780                 


Thr Cys Lys Met Gly Leu Val Ser Cys Gly Pro Pro Pro Glu Leu Pro 
785                 790                 795                 800 


Leu Ala Gln Val Phe Gly Arg Pro Arg Leu Arg Tyr Glu Val Asp Thr 
                805                 810                 815     


Val Leu Arg Tyr Arg Cys Arg Glu Gly Leu Ala Gln Arg Asn Leu Pro 
            820                 825                 830         


Leu Ile Arg Cys Gln Glu Asn Gly Arg Trp Glu Ala Pro Gln Ile Ser 
        835                 840                 845             


Cys Val Pro Arg Arg Pro Ala Arg Ala Leu His Pro Glu Glu Asp Pro 
    850                 855                 860                 


Glu Gly Arg Gln Gly Arg Leu Leu Gly Arg Trp Lys Ala Leu Leu Ile 
865                 870                 875                 880 


Pro Pro Ser Ser Pro Met Pro Gly Pro 
                885                 


<210>  61
<211>  331
<212>  PRT
<213>  Homo Sapiens

<400>  61

Asp Glu Glu Ala Ser Gly Ala Asp Thr Ser Gly Val Leu Asp Pro Asp 
1               5                   10                  15      


Ser Val Thr Pro Thr Tyr Ser Ala Met Cys Pro Phe Gly Cys His Cys 
            20                  25                  30          


His Leu Arg Val Val Gln Cys Ser Asp Leu Gly Leu Lys Ser Val Pro 
        35                  40                  45              


Lys Glu Ile Ser Pro Asp Thr Thr Leu Leu Asp Leu Gln Asn Asn Asp 
    50                  55                  60                  


Ile Ser Glu Leu Arg Lys Asp Asp Phe Lys Gly Leu Gln His Leu Tyr 
65                  70                  75                  80  


Ala Leu Val Leu Val Asn Asn Lys Ile Ser Lys Ile His Glu Lys Ala 
                85                  90                  95      


Phe Ser Pro Leu Arg Lys Leu Gln Lys Leu Tyr Ile Ser Lys Asn His 
            100                 105                 110         


Leu Val Glu Ile Pro Pro Asn Leu Pro Ser Ser Leu Val Glu Leu Arg 
        115                 120                 125             


Ile His Asp Asn Arg Ile Arg Lys Val Pro Lys Gly Val Phe Ser Gly 
    130                 135                 140                 


Leu Arg Asn Met Asn Cys Ile Glu Met Gly Gly Asn Pro Leu Glu Asn 
145                 150                 155                 160 


Ser Gly Phe Glu Pro Gly Ala Phe Asp Gly Leu Lys Leu Asn Tyr Leu 
                165                 170                 175     


Arg Ile Ser Glu Ala Lys Leu Thr Gly Ile Pro Lys Asp Leu Pro Glu 
            180                 185                 190         


Thr Leu Asn Glu Leu His Leu Asp His Asn Lys Ile Gln Ala Ile Glu 
        195                 200                 205             


Leu Glu Asp Leu Leu Arg Tyr Ser Lys Leu Tyr Arg Leu Gly Leu Gly 
    210                 215                 220                 


His Asn Gln Ile Arg Met Ile Glu Asn Gly Ser Leu Ser Phe Leu Pro 
225                 230                 235                 240 


Thr Leu Arg Glu Leu His Leu Asp Asn Asn Lys Leu Ala Arg Val Pro 
                245                 250                 255     


Ser Gly Leu Pro Asp Leu Lys Leu Leu Gln Val Val Tyr Leu His Ser 
            260                 265                 270         


Asn Asn Ile Thr Lys Val Gly Val Asn Asp Phe Cys Pro Met Gly Phe 
        275                 280                 285             


Gly Val Lys Arg Ala Tyr Tyr Asn Gly Ile Ser Leu Phe Asn Asn Pro 
    290                 295                 300                 


Val Pro Tyr Trp Glu Val Gln Pro Ala Thr Phe Arg Cys Val Thr Asp 
305                 310                 315                 320 


Arg Leu Ala Ile Gln Phe Gly Asn Tyr Lys Lys 
                325                 330     


<210>  62
<211>  866
<212>  PRT
<213>  Homo Sapiens

<400>  62

Ala Ala Thr Ser Arg Pro Glu Arg Val Trp Pro Asp Gly Val Ile Pro 
1               5                   10                  15      


Phe Val Ile Gly Gly Asn Phe Thr Gly Ser Gln Arg Ala Val Phe Arg 
            20                  25                  30          


Gln Ala Met Arg His Trp Glu Lys His Thr Cys Val Thr Phe Leu Glu 
        35                  40                  45              


Arg Thr Asp Glu Asp Ser Tyr Ile Val Phe Thr Tyr Arg Pro Cys Gly 
    50                  55                  60                  


Cys Cys Ser Tyr Val Gly Arg Arg Gly Gly Gly Pro Gln Ala Ile Ser 
65                  70                  75                  80  


Ile Gly Lys Asn Cys Asp Lys Phe Gly Ile Val Val His Glu Leu Gly 
                85                  90                  95      


His Val Val Gly Phe Trp His Glu His Thr Arg Pro Asp Arg Asp Arg 
            100                 105                 110         


His Val Ser Ile Val Arg Glu Asn Ile Gln Pro Gly Gln Glu Tyr Asn 
        115                 120                 125             


Phe Leu Lys Met Glu Pro Gln Glu Val Glu Ser Leu Gly Glu Thr Tyr 
    130                 135                 140                 


Asp Phe Asp Ser Ile Met His Tyr Ala Arg Asn Thr Phe Ser Arg Gly 
145                 150                 155                 160 


Ile Phe Leu Asp Thr Ile Val Pro Lys Tyr Glu Val Asn Gly Val Lys 
                165                 170                 175     


Pro Pro Ile Gly Gln Arg Thr Arg Leu Ser Lys Gly Asp Ile Ala Gln 
            180                 185                 190         


Ala Arg Lys Leu Tyr Lys Cys Pro Ala Cys Gly Glu Thr Leu Gln Asp 
        195                 200                 205             


Ser Thr Gly Asn Phe Ser Ser Pro Glu Tyr Pro Asn Gly Tyr Ser Ala 
    210                 215                 220                 


His Met His Cys Val Trp Arg Ile Ser Val Thr Pro Gly Glu Lys Ile 
225                 230                 235                 240 


Ile Leu Asn Phe Thr Ser Leu Asp Leu Tyr Arg Ser Arg Leu Cys Trp 
                245                 250                 255     


Tyr Asp Tyr Val Glu Val Arg Asp Gly Phe Trp Arg Lys Ala Pro Leu 
            260                 265                 270         


Arg Gly Arg Phe Cys Gly Ser Lys Leu Pro Glu Pro Ile Val Ser Thr 
        275                 280                 285             


Asp Ser Arg Leu Trp Val Glu Phe Arg Ser Ser Ser Asn Trp Val Gly 
    290                 295                 300                 


Lys Gly Phe Phe Ala Val Tyr Glu Ala Ile Cys Gly Gly Asp Val Lys 
305                 310                 315                 320 


Lys Asp Tyr Gly His Ile Gln Ser Pro Asn Tyr Pro Asp Asp Tyr Arg 
                325                 330                 335     


Pro Ser Lys Val Cys Ile Trp Arg Ile Gln Val Ser Glu Gly Phe His 
            340                 345                 350         


Val Gly Leu Thr Phe Gln Ser Phe Glu Ile Glu Arg His Asp Ser Cys 
        355                 360                 365             


Ala Tyr Asp Tyr Leu Glu Val Arg Asp Gly His Ser Glu Ser Ser Thr 
    370                 375                 380                 


Leu Ile Gly Arg Tyr Cys Gly Tyr Glu Lys Pro Asp Asp Ile Lys Ser 
385                 390                 395                 400 


Thr Ser Ser Arg Leu Trp Leu Lys Phe Val Ser Asp Gly Ser Ile Asn 
                405                 410                 415     


Lys Ala Gly Phe Ala Val Asn Phe Phe Lys Glu Val Asp Glu Cys Ser 
            420                 425                 430         


Arg Pro Asn Arg Gly Gly Cys Glu Gln Arg Cys Leu Asn Thr Leu Gly 
        435                 440                 445             


Ser Tyr Lys Cys Ser Cys Asp Pro Gly Tyr Glu Leu Ala Pro Asp Lys 
    450                 455                 460                 


Arg Arg Cys Glu Ala Ala Cys Gly Gly Phe Leu Thr Lys Leu Asn Gly 
465                 470                 475                 480 


Ser Ile Thr Ser Pro Gly Trp Pro Lys Glu Tyr Pro Pro Asn Lys Asn 
                485                 490                 495     


Cys Ile Trp Gln Leu Val Ala Pro Thr Gln Tyr Arg Ile Ser Leu Gln 
            500                 505                 510         


Phe Asp Phe Phe Glu Thr Glu Gly Asn Asp Val Cys Lys Tyr Asp Phe 
        515                 520                 525             


Val Glu Val Arg Ser Gly Leu Thr Ala Asp Ser Lys Leu His Gly Lys 
    530                 535                 540                 


Phe Cys Gly Ser Glu Lys Pro Glu Val Ile Thr Ser Gln Tyr Asn Asn 
545                 550                 555                 560 


Met Arg Val Glu Phe Lys Ser Asp Asn Thr Val Ser Lys Lys Gly Phe 
                565                 570                 575     


Lys Ala His Phe Phe Ser Asp Lys Asp Glu Cys Ser Lys Asp Asn Gly 
            580                 585                 590         


Gly Cys Gln Gln Asp Cys Ile Asn Thr Phe Gly Ser Tyr Glu Cys Gln 
        595                 600                 605             


Cys Arg Ser Gly Phe Val Leu His Asp Asn Lys His Asp Cys Lys Glu 
    610                 615                 620                 


Ala Gly Cys Asp His Lys Val Thr Ser Thr Ser Gly Thr Ile Thr Ser 
625                 630                 635                 640 


Pro Asn Trp Pro Asp Lys Tyr Pro Ser Lys Asn Glu Cys Thr Trp Ala 
                645                 650                 655     


Ile Ser Ser Thr Pro Gly His Arg Val Lys Leu Thr Phe Met Glu Met 
            660                 665                 670         


Asp Ile Glu Ser Gln Pro Glu Cys Ala Tyr Asp His Leu Glu Val Phe 
        675                 680                 685             


Asp Gly Arg Asp Ala Lys Ala Pro Val Leu Gly Arg Phe Cys Gly Ser 
    690                 695                 700                 


Lys Lys Pro Glu Pro Val Leu Ala Thr Gly Ser Arg Met Phe Leu Arg 
705                 710                 715                 720 


Phe Tyr Ser Asp Asn Ser Val Gln Arg Lys Gly Phe Gln Ala Ser His 
                725                 730                 735     


Ala Thr Glu Cys Gly Gly Gln Val Arg Ala Asp Val Lys Thr Lys Asp 
            740                 745                 750         


Leu Tyr Ser His Ala Gln Phe Gly Asp Asn Asn Tyr Pro Gly Gly Val 
        755                 760                 765             


Asp Cys Glu Trp Val Ile Val Ala Glu Glu Gly Tyr Gly Val Glu Leu 
    770                 775                 780                 


Val Phe Gln Thr Phe Glu Val Glu Glu Glu Thr Asp Cys Gly Tyr Asp 
785                 790                 795                 800 


Tyr Met Glu Leu Phe Asp Gly Tyr Asp Ser Thr Ala Pro Arg Leu Gly 
                805                 810                 815     


Arg Tyr Cys Gly Ser Gly Pro Pro Glu Glu Val Tyr Ser Ala Gly Asp 
            820                 825                 830         


Ser Val Leu Val Lys Phe His Ser Asp Asp Thr Ile Thr Lys Lys Gly 
        835                 840                 845             


Phe His Leu Arg Tyr Thr Ser Thr Lys Phe Gln Asp Thr Leu His Ser 
    850                 855                 860                 


Arg Lys 
865     


<210>  63
<211>  108
<212>  PRT
<213>  Homo Sapiens

<400>  63

Asn Ala Lys Gly Asn Tyr Cys Lys Arg Thr Pro Leu Tyr Ile Asp Phe 
1               5                   10                  15      


Lys Glu Ile Gly Trp Asp Ser Trp Ile Ile Ala Pro Pro Gly Tyr Glu 
            20                  25                  30          


Ala Tyr Glu Cys Arg Gly Val Cys Asn Tyr Pro Leu Ala Glu His Leu 
        35                  40                  45              


Thr Pro Thr Lys His Ala Ile Ile Gln Ala Leu Val His Leu Lys Asn 
    50                  55                  60                  


Ser Gln Lys Ala Ser Lys Ala Cys Cys Val Pro Thr Lys Leu Glu Pro 
65                  70                  75                  80  


Ile Ser Ile Leu Tyr Leu Asp Lys Gly Val Val Thr Tyr Lys Phe Lys 
                85                  90                  95      


Tyr Glu Gly Met Ala Val Ser Glu Cys Gly Cys Arg 
            100                 105             


<210>  64
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  64

Gln Ala Asp Gly Ile Ser Ala Glu Val Thr Ala Ser Ser Ser Lys His 
1               5                   10                  15      


Ser Gly Pro Glu Asn Asn Gln Cys Ser Leu His Pro Phe Gln Ile Ser 
            20                  25                  30          


Phe Arg Gln Leu Gly Trp Asp His Trp Ile Ile Ala Pro Pro Phe Tyr 
        35                  40                  45              


Thr Pro Asn Tyr Cys Lys Gly Thr Cys Leu Arg Val Leu Arg Asp Gly 
    50                  55                  60                  


Leu Asn Ser Pro Asn His Ala Ile Ile Gln Asn Leu Ile Asn Gln Leu 
65                  70                  75                  80  


Val Asp Gln Ser Val Pro Arg Pro Ser Cys Val Pro Tyr Lys Tyr Val 
                85                  90                  95      


Pro Ile Ser Val Leu Met Ile Glu Ala Asn Gly Ser Ile Leu Tyr Lys 
            100                 105                 110         


Glu Tyr Glu Gly Met Ile Ala Glu Ser Cys Thr Cys Arg 
        115                 120                 125 


<210>  65
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  65

Gln Ala Lys His Lys Gln Arg Lys Arg Leu Lys Ser Ser Cys Lys Arg 
1               5                   10                  15      


His Pro Leu Tyr Val Asp Phe Ser Asp Val Gly Trp Asn Asp Trp Ile 
            20                  25                  30          


Val Ala Pro Pro Gly Tyr His Ala Phe Tyr Cys His Gly Glu Cys Pro 
        35                  40                  45              


Phe Pro Leu Ala Asp His Leu Asn Ser Thr Asn His Ala Ile Val Gln 
    50                  55                  60                  


Thr Leu Val Asn Ser Val Asn Ser Lys Ile Pro Lys Ala Cys Cys Val 
65                  70                  75                  80  


Pro Thr Glu Leu Ser Ala Ile Ser Met Leu Tyr Leu Asp Glu Asn Glu 
                85                  90                  95      


Lys Val Val Leu Lys Asn Tyr Gln Asp Met Val Val Glu Gly Cys Gly 
            100                 105                 110         


Cys Arg 
        


<210>  66
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  66

Gln Trp Ile Glu Pro Arg Asn Cys Ala Arg Arg Tyr Leu Lys Val Asp 
1               5                   10                  15      


Phe Ala Asp Ile Gly Trp Ser Glu Trp Ile Ile Ser Pro Lys Ser Phe 
            20                  25                  30          


Asp Ala Tyr Tyr Cys Ser Gly Ala Cys Gln Phe Pro Met Pro Lys Ser 
        35                  40                  45              


Leu Lys Pro Ser Asn His Ala Thr Ile Gln Ser Ile Val Arg Ala Val 
    50                  55                  60                  


Gly Val Val Pro Gly Ile Pro Glu Pro Cys Cys Val Pro Glu Lys Met 
65                  70                  75                  80  


Ser Ser Leu Ser Ile Leu Phe Phe Asp Glu Asn Lys Asn Val Val Leu 
                85                  90                  95      


Lys Val Tyr Pro Asn Met Thr Val Glu Ser Cys Ala Cys Arg 
            100                 105                 110 


<210>  67
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  67

Ser Pro Lys His His Ser Gln Arg Ala Arg Lys Lys Asn Lys Asn Cys 
1               5                   10                  15      


Arg Arg His Ser Leu Tyr Val Asp Phe Ser Asp Val Gly Trp Asn Asp 
            20                  25                  30          


Trp Ile Val Ala Pro Pro Gly Tyr Gln Ala Phe Tyr Cys His Gly Asp 
        35                  40                  45              


Cys Pro Phe Pro Leu Ala Asp His Leu Asn Ser Thr Asn His Ala Ile 
    50                  55                  60                  


Val Gln Thr Leu Val Asn Ser Val Asn Ser Ser Ile Pro Lys Ala Cys 
65                  70                  75                  80  


Cys Val Pro Thr Glu Leu Ser Ala Ile Ser Met Leu Tyr Leu Asp Glu 
                85                  90                  95      


Tyr Asp Lys Val Val Leu Lys Asn Tyr Gln Glu Met Val Val Glu Gly 
            100                 105                 110         


Cys Gly Cys Arg 
        115     


<210>  68
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  68

Ala Ala Asn Lys Arg Lys Asn Gln Asn Arg Asn Lys Ser Ser Ser His 
1               5                   10                  15      


Gln Asp Ser Ser Arg Met Ser Ser Val Gly Asp Tyr Asn Thr Ser Glu 
            20                  25                  30          


Gln Lys Gln Ala Cys Lys Lys His Glu Leu Tyr Val Ser Phe Arg Asp 
        35                  40                  45              


Leu Gly Trp Gln Asp Trp Ile Ile Ala Pro Glu Gly Tyr Ala Ala Phe 
    50                  55                  60                  


Tyr Cys Asp Gly Glu Cys Ser Phe Pro Leu Asn Ala His Met Asn Ala 
65                  70                  75                  80  


Thr Asn His Ala Ile Val Gln Thr Leu Val His Leu Met Phe Pro Asp 
                85                  90                  95      


His Val Pro Lys Pro Cys Cys Ala Pro Thr Lys Leu Asn Ala Ile Ser 
            100                 105                 110         


Val Leu Tyr Phe Asp Asp Ser Ser Asn Val Ile Leu Lys Lys Tyr Arg 
        115                 120                 125             


Asn Met Val Val Arg Ser Cys Gly Cys His 
    130                 135             


<210>  69
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  69

Ser Thr Gly Ser Lys Gln Arg Ser Gln Asn Arg Ser Lys Thr Pro Lys 
1               5                   10                  15      


Asn Gln Glu Ala Leu Arg Met Ala Asn Val Ala Glu Asn Ser Ser Ser 
            20                  25                  30          


Asp Gln Arg Gln Ala Cys Lys Lys His Glu Leu Tyr Val Ser Phe Arg 
        35                  40                  45              


Asp Leu Gly Trp Gln Asp Trp Ile Ile Ala Pro Glu Gly Tyr Ala Ala 
    50                  55                  60                  


Tyr Tyr Cys Glu Gly Glu Cys Ala Phe Pro Leu Asn Ser Tyr Met Asn 
65                  70                  75                  80  


Ala Thr Asn His Ala Ile Val Gln Thr Leu Val His Phe Ile Asn Pro 
                85                  90                  95      


Glu Thr Val Pro Lys Pro Cys Cys Ala Pro Thr Gln Leu Asn Ala Ile 
            100                 105                 110         


Ser Val Leu Tyr Phe Asp Asp Ser Ser Asn Val Ile Leu Lys Lys Tyr 
        115                 120                 125             


Arg Asn Met Val Val Arg Ala Cys Gly Cys His 
    130                 135                 


<210>  70
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  70

Ala Val Arg Pro Leu Arg Arg Arg Gln Pro Lys Lys Ser Asn Glu Leu 
1               5                   10                  15      


Pro Gln Ala Asn Arg Leu Pro Gly Ile Phe Asp Asp Val Arg Gly Ser 
            20                  25                  30          


His Gly Arg Gln Val Cys Arg Arg His Glu Leu Tyr Val Ser Phe Gln 
        35                  40                  45              


Asp Leu Gly Trp Leu Asp Trp Val Ile Ala Pro Gln Gly Tyr Ser Ala 
    50                  55                  60                  


Tyr Tyr Cys Glu Gly Glu Cys Ser Phe Pro Leu Asp Ser Cys Met Asn 
65                  70                  75                  80  


Ala Thr Asn His Ala Ile Leu Gln Ser Leu Val His Leu Met Lys Pro 
                85                  90                  95      


Asn Ala Val Pro Lys Ala Cys Cys Ala Pro Thr Lys Leu Ser Ala Thr 
            100                 105                 110         


Ser Val Leu Tyr Tyr Asp Ser Ser Asn Asn Val Ile Leu Arg Lys His 
        115                 120                 125             


Arg Asn Met Val Val Lys Ala Cys Gly Cys His 
    130                 135                 


<210>  71
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  71

Ala Val Arg Pro Leu Arg Arg Arg Gln Pro Lys Lys Ser Asn Glu Leu 
1               5                   10                  15      


Pro Gln Ala Asn Arg Leu Pro Gly Ile Phe Asp Asp Val Arg Gly Ser 
            20                  25                  30          


His Gly Arg Gln Val Cys Arg Arg His Glu Leu Tyr Val Ser Phe Gln 
        35                  40                  45              


Asp Leu Gly Trp Leu Val Ile Ala Asp Ser Pro Cys Phe 
    50                  55                  60      


<210>  72
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  72

Gln Asn Leu Asp Ser Met Leu His Gly Thr Gly Met Lys Ser Asp Ser 
1               5                   10                  15      


Asp Gln Lys Lys Ser Glu Asn Gly Val Thr Leu Ala Pro Glu Asp Thr 
            20                  25                  30          


Leu Pro Phe Leu Lys Cys Tyr Cys Ser Gly His Cys Pro Asp Asp Ala 
        35                  40                  45              


Ile Asn Asn Thr Cys Ile Thr Asn Gly His Cys Phe Ala Ile Ile Glu 
    50                  55                  60                  


Glu Asp Asp Gln Gly Glu Thr Thr Leu Ala Ser Gly Cys Met Lys Tyr 
65                  70                  75                  80  


Glu Gly Ser Asp Phe Gln Cys Lys Asp Ser Pro Lys Ala Gln Leu Arg 
                85                  90                  95      


Arg Thr Ile Glu Cys Cys Arg Thr Asn Leu Cys Asn Gln Tyr Leu Gln 
            100                 105                 110         


Pro Thr Leu Pro Pro Val Val Ile Gly Pro Phe Phe Asp Gly Ser Ile 
        115                 120                 125             


Arg 
    


<210>  73
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  73

Lys Lys Glu Asp Gly Glu Ser Thr Ala Pro Thr Pro Arg Pro Lys Val 
1               5                   10                  15      


Leu Arg Cys Lys Cys His His His Cys Pro Glu Asp Ser Val Asn Asn 
            20                  25                  30          


Ile Cys Ser Thr Asp Gly Tyr Cys Phe Thr Met Ile Glu Glu Asp Asp 
        35                  40                  45              


Ser Gly Leu Pro Val Val Thr Ser Gly Cys Leu Gly Leu Glu Gly Ser 
    50                  55                  60                  


Asp Phe Gln Cys Arg Asp Thr Pro Ile Pro His Gln Arg Arg Ser Ile 
65                  70                  75                  80  


Glu Cys Cys Thr Glu Arg Asn Glu Cys Asn Lys Asp Leu His Pro Thr 
                85                  90                  95      


Leu Pro Pro Leu Lys Asn Arg Asp Phe Val Asp Gly Pro Ile His His 
            100                 105                 110         


Arg 
    


<210>  74
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  74

Ser Gln Asn Gln Glu Arg Leu Cys Ala Phe Lys Asp Pro Tyr Gln Gln 
1               5                   10                  15      


Asp Leu Gly Ile Gly Glu Ser Arg Ile Ser His Glu Asn Gly Thr Ile 
            20                  25                  30          


Leu Cys Ser Lys Gly Ser Thr Cys Tyr Gly Leu Trp Glu Lys Ser Lys 
        35                  40                  45              


Gly Asp Ile Asn Leu Val Lys Gln Gly Cys Trp Ser His Ile Gly Asp 
    50                  55                  60                  


Pro Gln Glu Cys His Tyr Glu Glu Cys Val Val Thr Thr Thr Pro Pro 
65                  70                  75                  80  


Ser Ile Gln Asn Gly Thr Tyr Arg Phe Cys Cys Cys Ser Thr Asp Leu 
                85                  90                  95      


Cys Asn Val Asn Phe Thr Glu Asn Phe Pro Pro Pro Asp Thr Thr Pro 
            100                 105                 110         


Leu Ser Pro Pro His Ser Phe Asn Arg Asp Glu Thr 
        115                 120                 


<210>  75
<211>  825
<212>  PRT
<213>  Homo Sapiens

<400>  75

Asp Leu Asn Glu Val Pro Gln Val Thr Val Gln Pro Ala Ser Thr Val 
1               5                   10                  15      


Gln Lys Pro Gly Gly Thr Val Ile Leu Gly Cys Val Val Glu Pro Pro 
            20                  25                  30          


Arg Met Asn Val Thr Trp Arg Leu Asn Gly Lys Glu Leu Asn Gly Ser 
        35                  40                  45              


Asp Asp Ala Leu Gly Val Leu Ile Thr His Gly Thr Leu Val Ile Thr 
    50                  55                  60                  


Ala Leu Asn Asn His Thr Val Gly Arg Tyr Gln Cys Val Ala Arg Met 
65                  70                  75                  80  


Pro Ala Gly Ala Val Ala Ser Val Pro Ala Thr Val Thr Leu Ala Asn 
                85                  90                  95      


Leu Gln Asp Phe Lys Leu Asp Val Gln His Val Ile Glu Val Asp Glu 
            100                 105                 110         


Gly Asn Thr Ala Val Ile Ala Cys His Leu Pro Glu Ser His Pro Lys 
        115                 120                 125             


Ala Gln Val Arg Tyr Ser Val Lys Gln Glu Trp Leu Glu Ala Ser Arg 
    130                 135                 140                 


Gly Asn Tyr Leu Ile Met Pro Ser Gly Asn Leu Gln Ile Val Asn Ala 
145                 150                 155                 160 


Ser Gln Glu Asp Glu Gly Met Tyr Lys Cys Ala Ala Tyr Asn Pro Val 
                165                 170                 175     


Thr Gln Glu Val Lys Thr Ser Gly Ser Ser Asp Arg Leu Arg Val Arg 
            180                 185                 190         


Arg Ser Thr Ala Glu Ala Ala Arg Ile Ile Tyr Pro Pro Glu Ala Gln 
        195                 200                 205             


Thr Ile Ile Val Thr Lys Gly Gln Ser Leu Ile Leu Glu Cys Val Ala 
    210                 215                 220                 


Ser Gly Ile Pro Pro Pro Arg Val Thr Trp Ala Lys Asp Gly Ser Ser 
225                 230                 235                 240 


Val Thr Gly Tyr Asn Lys Thr Arg Phe Leu Leu Ser Asn Leu Leu Ile 
                245                 250                 255     


Asp Thr Thr Ser Glu Glu Asp Ser Gly Thr Tyr Arg Cys Met Ala Asp 
            260                 265                 270         


Asn Gly Val Gly Gln Pro Gly Ala Ala Val Ile Leu Tyr Asn Val Gln 
        275                 280                 285             


Val Phe Glu Pro Pro Glu Val Thr Met Glu Leu Ser Gln Leu Val Ile 
    290                 295                 300                 


Pro Trp Gly Gln Ser Ala Lys Leu Thr Cys Glu Val Arg Gly Asn Pro 
305                 310                 315                 320 


Pro Pro Ser Val Leu Trp Leu Arg Asn Ala Val Pro Leu Ile Ser Ser 
                325                 330                 335     


Gln Arg Leu Arg Leu Ser Arg Arg Ala Leu Arg Val Leu Ser Met Gly 
            340                 345                 350         


Pro Glu Asp Glu Gly Val Tyr Gln Cys Met Ala Glu Asn Glu Val Gly 
        355                 360                 365             


Ser Ala His Ala Val Val Gln Leu Arg Thr Ser Arg Pro Ser Ile Thr 
    370                 375                 380                 


Pro Arg Leu Trp Gln Asp Ala Glu Leu Ala Thr Gly Thr Pro Pro Val 
385                 390                 395                 400 


Ser Pro Ser Lys Leu Gly Asn Pro Glu Gln Met Leu Arg Gly Gln Pro 
                405                 410                 415     


Ala Leu Pro Arg Pro Pro Thr Ser Val Gly Pro Ala Ser Pro Gln Cys 
            420                 425                 430         


Pro Gly Glu Lys Gly Gln Gly Ala Pro Ala Glu Ala Pro Ile Ile Leu 
        435                 440                 445             


Ser Ser Pro Arg Thr Ser Lys Thr Asp Ser Tyr Glu Leu Val Trp Arg 
    450                 455                 460                 


Pro Arg His Glu Gly Ser Gly Arg Ala Pro Ile Leu Tyr Tyr Val Val 
465                 470                 475                 480 


Lys His Arg Lys Val Thr Asn Ser Ser Asp Asp Trp Thr Ile Ser Gly 
                485                 490                 495     


Ile Pro Ala Asn Gln His Arg Leu Thr Leu Thr Arg Leu Asp Pro Gly 
            500                 505                 510         


Ser Leu Tyr Glu Val Glu Met Ala Ala Tyr Asn Cys Ala Gly Glu Gly 
        515                 520                 525             


Gln Thr Ala Met Val Thr Phe Arg Thr Gly Arg Arg Pro Lys Pro Glu 
    530                 535                 540                 


Ile Met Ala Ser Lys Glu Gln Gln Ile Gln Arg Asp Asp Pro Gly Ala 
545                 550                 555                 560 


Ser Pro Gln Ser Ser Ser Gln Pro Asp His Gly Arg Leu Ser Pro Pro 
                565                 570                 575     


Glu Ala Pro Asp Arg Pro Thr Ile Ser Thr Ala Ser Glu Thr Ser Val 
            580                 585                 590         


Tyr Val Thr Trp Ile Pro Arg Gly Asn Gly Gly Phe Pro Ile Gln Ser 
        595                 600                 605             


Phe Arg Val Glu Tyr Lys Lys Leu Lys Lys Val Gly Asp Trp Ile Leu 
    610                 615                 620                 


Ala Thr Ser Ala Ile Pro Pro Ser Arg Leu Ser Val Glu Ile Thr Gly 
625                 630                 635                 640 


Leu Glu Lys Gly Thr Ser Tyr Lys Phe Arg Val Arg Ala Leu Asn Met 
                645                 650                 655     


Leu Gly Glu Ser Glu Pro Ser Ala Pro Ser Arg Pro Tyr Val Val Ser 
            660                 665                 670         


Gly Tyr Ser Gly Arg Val Tyr Glu Arg Pro Val Ala Gly Pro Tyr Ile 
        675                 680                 685             


Thr Phe Thr Asp Ala Val Asn Glu Thr Thr Ile Met Leu Lys Trp Met 
    690                 695                 700                 


Tyr Ile Pro Ala Ser Asn Asn Asn Thr Pro Ile His Gly Phe Tyr Ile 
705                 710                 715                 720 


Tyr Tyr Arg Pro Thr Asp Ser Asp Asn Asp Ser Asp Tyr Lys Lys Asp 
                725                 730                 735     


Met Val Glu Gly Asp Lys Tyr Trp His Ser Ile Ser His Leu Gln Pro 
            740                 745                 750         


Glu Thr Ser Tyr Asp Ile Lys Met Gln Cys Phe Asn Glu Gly Gly Glu 
        755                 760                 765             


Ser Glu Phe Ser Asn Val Met Ile Cys Glu Thr Lys Ala Arg Lys Ser 
    770                 775                 780                 


Ser Gly Gln Pro Gly Arg Leu Pro Pro Pro Thr Leu Ala Pro Pro Gln 
785                 790                 795                 800 


Pro Pro Leu Pro Glu Thr Ile Glu Arg Pro Val Gly Thr Gly Ala Met 
                805                 810                 815     


Val Ala Arg Ser Ser Asp Leu Pro Tyr 
            820                 825 


<210>  76
<211>  186
<212>  PRT
<213>  Homo Sapiens

<400>  76

Ala Ala Gly Thr Val Phe Thr Thr Val Glu Asp Leu Gly Ser Lys Ile 
1               5                   10                  15      


Leu Leu Thr Cys Ser Leu Asn Asp Ser Ala Thr Glu Val Thr Gly His 
            20                  25                  30          


Arg Trp Leu Lys Gly Gly Val Val Leu Lys Glu Asp Ala Leu Pro Gly 
        35                  40                  45              


Gln Lys Thr Glu Phe Lys Val Asp Ser Asp Asp Gln Trp Gly Glu Tyr 
    50                  55                  60                  


Ser Cys Val Phe Leu Pro Glu Pro Met Gly Thr Ala Asn Ile Gln Leu 
65                  70                  75                  80  


His Gly Pro Pro Arg Val Lys Ala Val Lys Ser Ser Glu His Ile Asn 
                85                  90                  95      


Glu Gly Glu Thr Ala Met Leu Val Cys Lys Ser Glu Ser Val Pro Pro 
            100                 105                 110         


Val Thr Asp Trp Ala Trp Tyr Lys Ile Thr Asp Ser Glu Asp Lys Ala 
        115                 120                 125             


Leu Met Asn Gly Ser Glu Ser Arg Phe Phe Val Ser Ser Ser Gln Gly 
    130                 135                 140                 


Arg Ser Glu Leu His Ile Glu Asn Leu Asn Met Glu Ala Asp Pro Gly 
145                 150                 155                 160 


Gln Tyr Arg Cys Asn Gly Thr Ser Ser Lys Gly Ser Asp Gln Ala Ile 
                165                 170                 175     


Ile Thr Leu Arg Val Arg Ser His Leu Ala 
            180                 185     


<210>  77
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  77

Cys Ile Phe Pro Val Ile Leu Asn Glu Leu Ser Ser Thr Val Glu Thr 
1               5                   10                  15      


Ile Thr His Phe Pro Glu Val Thr Asp Gly Glu Cys Val Phe Pro Phe 
            20                  25                  30          


His Tyr Lys Asn Gly Thr Tyr Tyr Asp Cys Ile Lys Ser Lys Ala Arg 
        35                  40                  45              


His Lys Trp Cys Ser Leu Asn Lys Thr Tyr Glu Gly Tyr Trp Lys Phe 
    50                  55                  60                  


Cys Ser Ala Glu Asp Phe Ala Asn Cys Val Phe Pro Phe Trp Tyr Arg 
65                  70                  75                  80  


Arg Leu Ile Tyr Trp Glu Cys Thr Asp Asp Gly Glu Ala Phe Gly Lys 
                85                  90                  95      


Lys Trp Cys Ser Leu Thr Lys Asn Phe Asn Lys Asp Arg Ile Trp Lys 
            100                 105                 110         


Tyr Cys Glu 
        115 


<210>  78
<211>  80
<212>  PRT
<213>  Homo Sapiens

<400>  78

Asp Gly Asn Ser Thr Arg Ser Pro Glu Thr Asn Gly Leu Leu Cys Gly 
1               5                   10                  15      


Asp Pro Glu Glu Asn Cys Ala Ala Thr Thr Thr Gln Ser Lys Arg Lys 
            20                  25                  30          


Gly His Phe Ser Arg Cys Pro Lys Gln Tyr Lys His Tyr Cys Ile Lys 
        35                  40                  45              


Gly Arg Cys Arg Phe Val Val Ala Glu Gln Thr Pro Ser Cys Val Cys 
    50                  55                  60                  


Asp Glu Gly Tyr Ile Gly Ala Arg Cys Glu Arg Val Asp Leu Phe Tyr 
65                  70                  75                  80  


<210>  79
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  79

Lys Glu Ser Cys Asp Val Gln Leu Tyr Ile Lys Arg Gln Ser Glu His 
1               5                   10                  15      


Ser Ile Leu Ala Gly Asp Pro Phe Glu Leu Glu Cys Pro Val Lys Tyr 
            20                  25                  30          


Cys Ala Asn Arg Pro His Val Thr Trp Cys Lys Leu Asn Gly Thr Thr 
        35                  40                  45              


Cys Val Lys Leu Glu Asp Arg Gln Thr Ser Trp Lys Glu Glu Lys Asn 
    50                  55                  60                  


Ile Ser Phe Phe Ile Leu His Phe Glu Pro Val Leu Pro Asn Asp Asn 
65                  70                  75                  80  


Gly Ser Tyr Arg Cys Ser Ala Asn Phe Gln Ser Asn Leu Ile Glu Ser 
                85                  90                  95      


His Ser Thr Thr Leu Tyr Val Thr 
            100                 


<210>  80
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  80

Ala Pro Phe Asp Val Ile Gly Pro Pro Glu Pro Ile Leu Ala Val Val 
1               5                   10                  15      


Gly Glu Asp Ala Glu Leu Pro Cys Arg Leu Ser Pro Asn Ala Ser Ala 
            20                  25                  30          


Glu His Leu Glu Leu Arg Trp Phe Arg Lys Lys Val Ser Pro Ala Val 
        35                  40                  45              


Leu Val His Arg Asp Gly Arg Glu Gln Glu Ala Glu Gln Met Pro Glu 
    50                  55                  60                  


Tyr Arg Gly Arg Ala Thr Leu Val Gln Asp Gly Ile Ala Lys Gly Arg 
65                  70                  75                  80  


Val Ala Leu Arg Ile Arg Gly Val Arg Val Ser Asp Asp Gly Glu Tyr 
                85                  90                  95      


Thr Cys Phe Phe Arg Glu Asp Gly Ser Tyr Glu Glu Ala Leu Val His 
            100                 105                 110         


Leu Lys Val Ala Ala Leu Gly Ser Asp Pro His Ile Ser Met Gln Val 
        115                 120                 125             


Gln Glu Asn Gly Glu Ile Cys Leu Glu Cys Thr Ser Val Gly Trp Tyr 
    130                 135                 140                 


Pro Glu Pro Gln Val Gln Trp Arg Thr Ser Lys Gly Glu Lys Phe Pro 
145                 150                 155                 160 


Ser Thr Ser Glu Ser Arg Asn Pro Asp Glu Glu Gly Leu Phe Thr Val 
                165                 170                 175     


Ala Ala Ser Val Ile Ile Arg Asp Thr Ser Ala Lys Asn Val Ser Cys 
            180                 185                 190         


Tyr Ile Gln Asn Leu Leu Leu Gly Gln Glu Lys Lys Val Glu Ile Ser 
        195                 200                 205             


Ile Pro Ala Ser Ser Leu Pro Arg 
    210                 215     


<210>  81
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  81

Gln Phe Ile Val Val Gly Pro Thr Asp Pro Ile Leu Ala Thr Val Gly 
1               5                   10                  15      


Glu Asn Thr Thr Leu Arg Cys His Leu Ser Pro Glu Lys Asn Ala Glu 
            20                  25                  30          


Asp Met Glu Val Arg Trp Phe Arg Ser Gln Phe Ser Pro Ala Val Phe 
        35                  40                  45              


Val Tyr Lys Gly Gly Arg Glu Arg Thr Glu Glu Gln Met Glu Glu Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Thr Phe Val Ser Lys Asp Ile Ser Arg Gly Ser Val 
65                  70                  75                  80  


Ala Leu Val Ile His Asn Ile Thr Ala Gln Glu Asn Gly Thr Tyr Arg 
                85                  90                  95      


Cys Tyr Phe Gln Glu Gly Arg Ser Tyr Asp Glu Ala Ile Leu His Leu 
            100                 105                 110         


Val Val Ala Gly Leu Gly Ser Lys Pro Leu Ile Ser Met Arg Gly His 
        115                 120                 125             


Glu Asp Gly Gly Ile Arg Leu Glu Cys Ile Ser Arg Gly Trp Tyr Pro 
    130                 135                 140                 


Lys Pro Leu Thr Val Trp Arg Asp Pro Tyr Gly Gly Val Ala Pro Ala 
145                 150                 155                 160 


Leu Lys Glu Val Ser Met Pro Asp Ala Asp Gly Leu Phe Met Val Thr 
                165                 170                 175     


Thr Ala Val Ile Ile Arg Asp Lys Ser Val Arg Asn Met Ser Cys Ser 
            180                 185                 190         


Ile Asn Asn Thr Leu Leu Gly Gln Lys Lys Glu Ser Val Ile Phe Ile 
        195                 200                 205             


Pro Glu Ser Phe Met Pro Ser Val Ser Pro Cys Ala 
    210                 215                 220 


<210>  82
<211>  233
<212>  PRT
<213>  Homo Sapiens

<400>  82

Gln Phe Thr Val Val Gly Pro Ala Asn Pro Ile Leu Ala Met Val Gly 
1               5                   10                  15      


Glu Asn Thr Thr Leu Arg Cys His Leu Ser Pro Glu Lys Asn Ala Glu 
            20                  25                  30          


Asp Met Glu Val Arg Trp Phe Arg Ser Gln Phe Ser Pro Ala Val Phe 
        35                  40                  45              


Val Tyr Lys Gly Gly Arg Glu Arg Thr Glu Glu Gln Met Glu Glu Tyr 
    50                  55                  60                  


Arg Gly Arg Ile Thr Phe Val Ser Lys Asp Ile Asn Arg Gly Ser Val 
65                  70                  75                  80  


Ala Leu Val Ile His Asn Val Thr Ala Gln Glu Asn Gly Ile Tyr Arg 
                85                  90                  95      


Cys Tyr Phe Gln Glu Gly Arg Ser Tyr Asp Glu Ala Ile Leu Arg Leu 
            100                 105                 110         


Val Val Ala Gly Leu Gly Ser Lys Pro Leu Ile Glu Ile Lys Ala Gln 
        115                 120                 125             


Glu Asp Gly Ser Ile Trp Leu Glu Cys Ile Ser Gly Gly Trp Tyr Pro 
    130                 135                 140                 


Glu Pro Leu Thr Val Trp Arg Asp Pro Tyr Gly Glu Val Val Pro Ala 
145                 150                 155                 160 


Leu Lys Glu Val Ser Ile Ala Asp Ala Asp Gly Leu Phe Met Val Thr 
                165                 170                 175     


Thr Ala Val Ile Ile Arg Asp Lys Tyr Val Arg Asn Val Ser Cys Ser 
            180                 185                 190         


Val Asn Asn Thr Leu Leu Gly Gln Glu Lys Glu Thr Val Ile Phe Ile 
        195                 200                 205             


Pro Glu Ser Phe Met Pro Ser Ala Ser Pro Trp Met Val Ala Leu Ala 
    210                 215                 220                 


Val Ile Leu Thr Ala Ser Pro Trp Met 
225                 230             


<210>  83
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  83

Gln Val Thr Val Val Gly Pro Thr Asp Pro Ile Leu Ala Met Val Gly 
1               5                   10                  15      


Glu Asn Thr Thr Leu Arg Cys Cys Leu Ser Pro Glu Glu Asn Ala Glu 
            20                  25                  30          


Asp Met Glu Val Arg Trp Phe Gln Ser Gln Phe Ser Pro Ala Val Phe 
        35                  40                  45              


Val Tyr Lys Gly Gly Arg Glu Arg Thr Glu Glu Gln Lys Glu Glu Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Thr Phe Val Ser Lys Asp Ser Arg Gly Ser Val Ala 
65                  70                  75                  80  


Leu Ile Ile His Asn Val Thr Ala Glu Asp Asn Gly Ile Tyr Gln Cys 
                85                  90                  95      


Tyr Phe Gln Glu Gly Arg Ser Cys Asn Glu Ala Ile Leu His Leu Val 
            100                 105                 110         


<210>  84
<211>  225
<212>  PRT
<213>  Homo Sapiens

<400>  84

Gln Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly 
1               5                   10                  15      


Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala Glu 
            20                  25                  30          


Thr Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val Val Asn 
        35                  40                  45              


Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser Ala Pro Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr Ala Gly Lys Ala 
65                  70                  75                  80  


Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp Ser Gly Lys Tyr Leu 
                85                  90                  95      


Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu Lys Ala Leu Val Glu Leu 
            100                 105                 110         


Lys Val Ala Ala Leu Gly Ser Asp Leu His Val Asp Val Lys Gly Tyr 
        115                 120                 125             


Lys Asp Gly Gly Ile His Leu Glu Cys Arg Ser Thr Gly Trp Tyr Pro 
    130                 135                 140                 


Gln Pro Gln Ile Gln Trp Ser Asn Asn Lys Gly Glu Asn Ile Pro Thr 
145                 150                 155                 160 


Val Glu Ala Pro Val Val Ala Asp Gly Val Gly Leu Tyr Ala Val Ala 
                165                 170                 175     


Ala Ser Val Ile Met Arg Gly Ser Ser Gly Glu Gly Val Ser Cys Thr 
            180                 185                 190         


Ile Arg Ser Ser Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile 
        195                 200                 205             


Ala Asp Pro Phe Phe Arg Ser Ala Gln Arg Trp Ile Ala Ala Leu Ala 
    210                 215                 220                 


Gly 
225 


<210>  85
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  85

Gln Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly 
1               5                   10                  15      


Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala Glu 
            20                  25                  30          


Thr Met Glu Leu Lys Trp Val Ser Ser Ser Leu Arg Gln Val Val Asn 
        35                  40                  45              


Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser Ala Pro Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr Ala Gly Lys Ala 
65                  70                  75                  80  


Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp Ser Gly Lys Tyr Leu 
                85                  90                  95      


Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu Lys Ala Leu Val Glu Leu 
            100                 105                 110         


Lys Val Ala Ala Leu Gly Ser Asn Leu His Val Glu Val Lys Gly Tyr 
        115                 120                 125             


Glu Asp Gly Gly Ile His Leu Glu Cys Arg Ser Thr Gly Trp Tyr Pro 
    130                 135                 140                 


Gln Pro Gln Ile Gln Trp Ser Asn Ala Lys Gly Glu Asn Ile Pro Ala 
145                 150                 155                 160 


Val Glu Ala Pro Val Val Ala Asp Gly Val Gly Leu Tyr Glu Val Ala 
                165                 170                 175     


Ala Ser Val Ile Met Arg Gly Gly Ser Gly Glu Gly Val Ser Cys Ile 
            180                 185                 190         


Ile Arg Asn Ser Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile 
        195                 200                 205             


Ala Asp Pro Phe Phe Arg Ser Ala Gln Pro Trp 
    210                 215                 


<210>  86
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  86

Gln Phe Ser Val Leu Gly Pro Ser Gly Pro Ile Leu Ala Met Val Gly 
1               5                   10                  15      


Glu Asp Ala Asp Leu Pro Cys His Leu Phe Pro Thr Met Ser Ala Glu 
            20                  25                  30          


Thr Met Glu Leu Arg Trp Val Ser Ser Ser Leu Arg Gln Val Val Asn 
        35                  40                  45              


Val Tyr Ala Asp Gly Lys Glu Val Glu Asp Arg Gln Ser Ala Pro Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Ser Ile Leu Arg Asp Gly Ile Thr Ala Gly Lys Ala 
65                  70                  75                  80  


Ala Leu Arg Ile His Asn Val Thr Ala Ser Asp Ser Gly Lys Tyr Leu 
                85                  90                  95      


Cys Tyr Phe Gln Asp Gly Asp Phe Tyr Glu Lys Ala Leu Val Glu Leu 
            100                 105                 110         


Lys Val Ala Ala Leu Gly Ser Asp Leu His Ile Glu Val Lys Gly Tyr 
        115                 120                 125             


Glu Asp Gly Gly Ile His Leu Glu Cys Arg Ser Thr Gly Trp Tyr Pro 
    130                 135                 140                 


Gln Pro Gln Ile Lys Trp Ser Asp Thr Lys Gly Glu Asn Ile Pro Ala 
145                 150                 155                 160 


Val Glu Ala Pro Val Val Ala Asp Gly Val Gly Leu Tyr Ala Val Ala 
                165                 170                 175     


Ala Ser Val Ile Met Arg Gly Ser Ser Gly Gly Gly Val Ser Cys Ile 
            180                 185                 190         


Ile Arg Asn Ser Leu Leu Gly Leu Glu Lys Thr Ala Ser Ile Ser Ile 
        195                 200                 205             


Ala Asp Pro Phe Phe Arg Ser Ala Gln Pro Trp 
    210                 215                 


<210>  87
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  87

Ser Ile Trp Lys Ala Asp Phe Asp Val Thr Gly Pro His Ala Pro Ile 
1               5                   10                  15      


Leu Ala Met Ala Gly Gly His Val Glu Leu Gln Cys Gln Leu Phe Pro 
            20                  25                  30          


Asn Ile Ser Ala Glu Asp Met Glu Leu Arg Trp Tyr Arg Cys Gln Pro 
        35                  40                  45              


Ser Leu Ala Val His Met His Glu Arg Gly Met Asp Met Asp Gly Glu 
    50                  55                  60                  


Gln Lys Trp Gln Tyr Arg Gly Arg Thr Thr Phe Met Ser Asp His Val 
65                  70                  75                  80  


Ala Arg Gly Lys Ala Met Val Arg Ser His Arg Val Thr Thr Phe Asp 
                85                  90                  95      


Asn Arg Thr Tyr Cys Cys Arg Phe Lys Asp Gly Val Lys Phe Gly Glu 
            100                 105                 110         


Ala Thr Val Gln Val Gln Val Ala Gly Leu Gly Arg Glu Pro Arg Ile 
        115                 120                 125             


Gln Val Thr Asp Gln Gln Asp Gly Val Arg Ala Glu Cys Thr Ser Ala 
    130                 135                 140                 


Gly Cys Phe Pro Lys Ser Trp Val Glu Arg Arg Asp Phe Arg Gly Gln 
145                 150                 155                 160 


Ala Arg Pro Ala Val Thr Asn Leu Ser Ala Ser Ala Thr Thr Arg Leu 
                165                 170                 175     


Trp Ala Val Ala Ser Ser Leu Thr Leu Trp Asp Arg Ala Val Glu Gly 
            180                 185                 190         


Leu Ser Cys Ser Ile Ser Ser Pro Leu Leu Pro Glu Arg Arg Lys Val 
        195                 200                 205             


Ala Glu Ser His Leu Pro Ala Thr Phe Ser Arg Ser Ser Gln Phe Thr 
    210                 215                 220                 


Ala Trp Lys Ala 
225             


<210>  88
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  88

Pro Glu Lys Leu Gln Thr Glu Leu Ala Ser Leu Lys Val Asn Gly Pro 
1               5                   10                  15      


Ser Gln Pro Ile Leu Val Arg Val Gly Glu Asp Ile Gln Leu Thr Cys 
            20                  25                  30          


Tyr Leu Ser Pro Lys Ala Asn Ala Gln Ser Met Glu Val Arg Trp Asp 
        35                  40                  45              


Arg Ser His Arg Tyr Pro Ala Val His Val Tyr Met Asp Gly Asp His 
    50                  55                  60                  


Val Ala Gly Glu Gln Met Ala Glu Tyr Arg Gly Arg Thr Val Leu Val 
65                  70                  75                  80  


Ser Asp Ala Ile Asp Glu Gly Arg Leu Thr Leu Gln Ile Leu Ser Ala 
                85                  90                  95      


Arg Pro Ser Asp Asp Gly Gln Tyr Arg Cys Leu Phe Glu Lys Asp Asp 
            100                 105                 110         


Val Tyr Gln Glu Ala Ser Leu Asp Leu Lys Val Val Gly Leu Gly Ser 
        115                 120                 125             


Ser Pro Leu Ile Thr Val Glu Gly Gln Glu Asp Gly Glu Met Gln Pro 
    130                 135                 140                 


Met Cys Ser Ser Asp Gly Trp Phe Pro Gln Pro His Val Pro Trp Arg 
145                 150                 155                 160 


Asp Met Glu Gly Lys Thr Ile Pro Ser Ser Ser Gln Ala Leu Thr Gln 
                165                 170                 175     


Gly Ser His Gly Leu Phe His Val Gln Thr Leu Leu Arg Val Thr Asn 
            180                 185                 190         


Ile Ser Ala Val Asp Val Thr Cys Ser Ile Ser Ile Pro Phe Leu Gly 
        195                 200                 205             


Glu Glu Lys Ile Ala Thr Phe Ser Leu Ser Gly Trp 
    210                 215                 220 


<210>  89
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  89

Gln Trp Gln Val Thr Gly Pro Gly Lys Phe Val Gln Ala Leu Val Gly 
1               5                   10                  15      


Glu Asp Ala Val Phe Ser Cys Ser Leu Phe Pro Glu Thr Ser Ala Glu 
            20                  25                  30          


Ala Met Glu Val Arg Phe Phe Arg Asn Gln Phe His Ala Val Val His 
        35                  40                  45              


Leu Tyr Arg Asp Gly Glu Asp Trp Glu Ser Lys Gln Met Pro Gln Tyr 
    50                  55                  60                  


Arg Gly Arg Thr Glu Phe Val Lys Asp Ser Ile Ala Gly Gly Arg Val 
65                  70                  75                  80  


Ser Leu Arg Leu Lys Asn Ile Thr Pro Ser Asp Ile Gly Leu Tyr Gly 
                85                  90                  95      


Cys Trp Phe Ser Ser Gln Ile Tyr Asp Glu Glu Ala Thr Trp Glu Leu 
            100                 105                 110         


Arg Val Ala Ala Leu Gly Ser Leu Pro Leu Ile Ser Ile Val Gly Tyr 
        115                 120                 125             


Val Asp Gly Gly Ile Gln Leu Leu Cys Leu Ser Ser Gly Trp Phe Pro 
    130                 135                 140                 


Gln Pro Thr Ala Lys Trp Lys Gly Pro Gln Gly Gln Asp Leu Ser Ser 
145                 150                 155                 160 


Asp Ser Arg Ala Asn Ala Asp Gly Tyr Ser Leu Tyr Asp Val Glu Ile 
                165                 170                 175     


Ser Ile Ile Val Gln Glu Asn Ala Gly Ser Ile Leu Cys Ser Ile His 
            180                 185                 190         


Leu Ala Glu Gln Ser His Glu Val Glu Ser Lys Val Leu Ile Gly Glu 
        195                 200                 205             


Thr Phe Phe Gln Pro Ser Pro Trp Arg Leu Ala Ser 
    210                 215                 220 


<210>  90
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  90

Ala Leu Gly Ser Val Pro Leu Ile Ser Ile Ala Gly Tyr Val Asp Arg 
1               5                   10                  15      


Asp Ile Gln Leu Leu Cys Gln Ser Ser Gly Trp Phe Pro Arg Pro Thr 
            20                  25                  30          


Ala Lys Trp Lys Gly Pro Gln Gly Gln Asp Leu Ser Thr Asp Ser Arg 
        35                  40                  45              


Thr Asn Arg Asp Met His Gly Leu Phe Asp Val Glu Ile Ser Leu Thr 
    50                  55                  60                  


Val Gln Glu Asn Ala Gly Ser Ile Ser Cys Ser Met Arg His Ala His 
65                  70                  75                  80  


Leu Ser Arg Glu Val Glu Ser Arg Val Gln Ile Gly Asp Thr Phe Phe 
                85                  90                  95      


Lys Pro Ile Ser Trp His Leu Ala Thr Lys 
            100                 105     


<210>  91
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  91

Ser Ser Glu Val Lys Val Leu Gly Pro Glu Tyr Pro Ile Leu Ala Leu 
1               5                   10                  15      


Val Gly Glu Glu Val Glu Phe Pro Cys His Leu Trp Pro Gln Leu Asp 
            20                  25                  30          


Ala Gln Gln Met Glu Ile Arg Trp Phe Arg Ser Gln Thr Phe Asn Val 
        35                  40                  45              


Val His Leu Tyr Gln Glu Gln Gln Glu Leu Pro Gly Arg Gln Met Pro 
    50                  55                  60                  


Ala Phe Arg Asn Arg Thr Lys Leu Val Lys Asp Asp Ile Ala Tyr Gly 
65                  70                  75                  80  


Ser Val Val Leu Gln Leu His Ser Ile Ile Pro Ser Asp Lys Gly Thr 
                85                  90                  95      


Tyr Gly Cys Arg Phe His Ser Asp Asn Phe Ser Gly Glu Ala Leu Trp 
            100                 105                 110         


Glu Leu Glu Val Ala Gly Leu Gly Ser Asp Pro His Leu Ser Leu Glu 
        115                 120                 125             


Gly Phe Lys Glu Gly Gly Ile Gln Leu Arg Leu Arg Ser Ser Gly Trp 
    130                 135                 140                 


Tyr Pro Lys Pro Lys Val Gln Trp Arg Asp His Gln Gly Gln Cys Leu 
145                 150                 155                 160 


Pro Pro Glu Phe Glu Ala Ile Val Trp Asp Ala Gln Asp Leu Phe Ser 
                165                 170                 175     


Leu Glu Thr Ser Val Val Val Arg Ala Gly Ala Leu Ser Asn Val Ser 
            180                 185                 190         


Val Ser Ile Gln Asn Leu Leu Leu Ser Gln Lys Lys Glu Leu Val Val 
        195                 200                 205             


Gln Ile Ala Asp Val Phe Val Pro Gly Ala Ser Ala Trp Lys 
    210                 215                 220         


<210>  92
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  92

Ile Asn Ile Thr Ser Ser Ala Ser Gln Glu Gly Thr Arg Leu Asn Leu 
1               5                   10                  15      


Ile Cys Thr Val Trp His Lys Lys Glu Glu Ala Glu Gly Phe Val Val 
            20                  25                  30          


Phe Leu Cys Lys Asp Arg Ser Gly Asp Cys Ser Pro Glu Thr Ser Leu 
        35                  40                  45              


Lys Gln Leu Arg Leu Lys Arg Asp Pro Gly Ile Asp Gly Val Gly Glu 
    50                  55                  60                  


Ile Ser Ser Gln Leu Met Phe Thr Ile Ser Gln Val Thr Pro Leu His 
65                  70                  75                  80  


Ser Gly Thr Tyr Gln Cys Cys Ala Arg Ser Gln Lys Ser Gly Ile Arg 
                85                  90                  95      


Leu Gln Gly His Phe Phe Ser Ile Leu Phe Thr Glu Thr Gly Asn Tyr 
            100                 105                 110         


Thr Val Thr Gly Leu Lys Gln Arg Gln His Leu Glu Phe Ser His Asn 
        115                 120                 125             


Glu Gly Thr Leu Ser 
    130             


<210>  93
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  93

Phe Lys Val Ala Thr Pro Tyr Ser Leu Tyr Val Cys Pro Glu Gly Gln 
1               5                   10                  15      


Asn Val Thr Leu Thr Cys Arg Leu Leu Gly Pro Val Asp Lys Gly His 
            20                  25                  30          


Asp Val Thr Phe Tyr Lys Thr Trp Tyr Arg Ser Ser Arg Gly Glu Val 
        35                  40                  45              


Gln Thr Cys Ser Glu Arg Arg Pro Ile Arg Asn Leu Thr Phe Gln Asp 
    50                  55                  60                  


Leu His Leu His His Gly Gly His Gln Ala Ala Asn Thr Ser His Asp 
65                  70                  75                  80  


Leu Ala Gln Arg His Gly Leu Glu Ser Ala Ser Asp His His Gly Asn 
                85                  90                  95      


Phe Ser Ile Thr Met Arg Asn Leu Thr Leu Leu Asp Ser Gly Leu Tyr 
            100                 105                 110         


Cys Cys Leu Val Val Glu Ile Arg His His His Ser Glu His Arg Val 
        115                 120                 125             


His Gly Ala Met Glu Leu Gln Val Gln Thr Gly Lys Asp Ala Pro Ser 
    130                 135                 140                 


Asn Cys Val Val Tyr Pro Ser Ser Ser Gln Glu Ser Glu Asn Ile Thr 
145                 150                 155                 160 


Ala Ala 
        


<210>  94
<211>  325
<212>  PRT
<213>  Homo Sapiens

<400>  94

Ala Leu Leu Arg Arg Gln Thr Ser Gly Pro Leu Tyr Leu Ala Val Trp 
1               5                   10                  15      


Asp Lys Ala Asp Asp Ser Gly Gly Arg Met Thr Thr Ala Cys Ser Pro 
            20                  25                  30          


His Asn Pro Gln Cys Thr Ala Asp Leu Gly Ala Gln Tyr Ile Thr Cys 
        35                  40                  45              


Thr Pro His Tyr Ala Lys Lys His Gln Arg Phe Tyr Asp Glu Leu Leu 
    50                  55                  60                  


Ala Tyr Gly Val Leu Arg Pro Leu Ser Ser Pro Ile Glu Gly Met Val 
65                  70                  75                  80  


Met Lys Glu Gly Asp Cys Asn Phe Val Ala Pro Gln Gly Ile Ser Ser 
                85                  90                  95      


Ile Ile Lys His Tyr Leu Lys Glu Ser Gly Ala Glu Val Tyr Phe Arg 
            100                 105                 110         


His Arg Val Thr Gln Ile Asn Leu Arg Asp Asp Lys Trp Glu Val Ser 
        115                 120                 125             


Lys Gln Thr Gly Ser Pro Glu Gln Phe Asp Leu Ile Val Leu Thr Met 
    130                 135                 140                 


Pro Val Pro Glu Ile Leu Gln Leu Gln Gly Asp Ile Thr Thr Leu Ile 
145                 150                 155                 160 


Ser Glu Cys Gln Arg Gln Gln Leu Glu Ala Val Ser Tyr Ser Ser Arg 
                165                 170                 175     


Tyr Ala Leu Gly Leu Phe Tyr Glu Ala Gly Thr Lys Ile Asp Val Pro 
            180                 185                 190         


Trp Ala Gly Gln Tyr Ile Thr Ser Asn Pro Cys Ile Arg Phe Val Ser 
        195                 200                 205             


Ile Asp Asn Lys Lys Arg Asn Ile Glu Ser Ser Glu Ile Gly Pro Ser 
    210                 215                 220                 


Leu Val Ile His Thr Thr Val Pro Phe Gly Val Thr Tyr Leu Glu His 
225                 230                 235                 240 


Ser Ile Glu Asp Val Gln Glu Leu Val Phe Gln Gln Leu Glu Asn Ile 
                245                 250                 255     


Leu Pro Gly Leu Pro Gln Pro Ile Ala Thr Lys Cys Gln Lys Trp Arg 
            260                 265                 270         


His Ser Gln Val Thr Asn Ala Ala Ala Asn Cys Pro Gly Gln Met Thr 
        275                 280                 285             


Leu His His Lys Pro Phe Leu Ala Cys Gly Gly Asp Gly Phe Thr Gln 
    290                 295                 300                 


Ser Asn Phe Asp Gly Cys Ile Thr Ser Ala Leu Cys Val Leu Glu Ala 
305                 310                 315                 320 


Leu Lys Asn Tyr Ile 
                325 


<210>  95
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  95

Arg Glu Glu Glu Ile Thr Pro Val Val Ser Ile Ala Tyr Lys Val Leu 
1               5                   10                  15      


Glu Val Phe Pro Lys Gly Arg Trp Val Leu Ile Thr Cys Cys Ala Pro 
            20                  25                  30          


Gln Pro Pro Pro Pro Ile Thr Tyr Ser Leu Cys Gly Thr Lys Asn Ile 
        35                  40                  45              


Lys Val Ala Lys Lys Val Val Lys Thr His Glu Pro Ala Ser Phe Asn 
    50                  55                  60                  


Leu Asn Val Thr Leu Lys Ser Ser Pro Asp Leu Leu Thr Tyr Phe Cys 
65                  70                  75                  80  


Trp Ala Ser Ser Thr Ser Gly Ala His Val Asp Ser Ala Arg Leu Gln 
                85                  90                  95      


Met His Trp Glu Leu Trp Ser Lys Pro Val Ser Glu Leu Arg Ala Asn 
            100                 105                 110         


Phe Thr Leu Gln Asp Arg Gly Ala Gly Pro Arg Val Glu Met Ile Cys 
        115                 120                 125             


Gln Ala Ser Ser Gly Ser Pro Pro Ile Thr Asn Ser Leu Ile Gly Lys 
    130                 135                 140                 


Asp Gly Gln Val His Leu Gln Gln Arg Pro Cys His Arg Gln Pro Ala 
145                 150                 155                 160 


Asn Phe Ser Phe Leu Pro Ser Gln Thr Ser Asp Trp Phe Trp Cys Gln 
                165                 170                 175     


Ala Ala Asn Asn Ala Asn Val Gln His Ser Ala Leu Thr Val Val Pro 
            180                 185                 190         


Pro Gly Gly Asp Gln Lys Met Glu Asp Trp Gln Gly Pro Leu Glu Ser 
        195                 200                 205             


Pro Ile Leu Ala Leu Pro Leu Tyr Arg Ser Thr Arg Arg Leu Ser Glu 
    210                 215                 220                 


Glu Glu Phe Gly Gly Phe Arg Ile Gly Asn Gly Glu Val Arg Gly Arg 
225                 230                 235                 240 


Lys Ala Ala Ala Met 
                245 


<210>  96
<211>  142
<212>  PRT
<213>  Homo Sapiens

<400>  96

Val Ser Glu Pro Thr Thr Val Ala Phe Asp Val Arg Pro Gly Gly Val 
1               5                   10                  15      


Val His Ser Phe Ser His Asn Val Gly Pro Gly Asp Lys Tyr Thr Cys 
            20                  25                  30          


Met Phe Thr Tyr Ala Ser Gln Gly Gly Thr Asn Glu Gln Trp Gln Met 
        35                  40                  45              


Ser Leu Gly Thr Ser Glu Asp His Gln His Phe Thr Cys Thr Ile Trp 
    50                  55                  60                  


Arg Pro Gln Gly Lys Ser Tyr Leu Tyr Phe Thr Gln Phe Lys Ala Glu 
65                  70                  75                  80  


Val Arg Gly Ala Glu Ile Glu Tyr Ala Met Ala Tyr Ser Lys Ala Ala 
                85                  90                  95      


Phe Glu Arg Glu Ser Asp Val Pro Leu Lys Thr Glu Glu Phe Glu Val 
            100                 105                 110         


Thr Lys Thr Ala Val Ala His Arg Pro Gly Ala Phe Lys Ala Glu Leu 
        115                 120                 125             


Ser Lys Leu Val Ile Val Ala Lys Ala Ser Arg Thr Glu Leu 
    130                 135                 140         


<210>  97
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  97

Ala Ala Pro Thr Pro Pro Gly Trp Glu Pro Thr Pro Asp Ala Pro Trp 
1               5                   10                  15      


Cys Pro Tyr Lys Val Leu Pro Glu Gly Pro Glu Ala Gly Gly Gly Arg 
            20                  25                  30          


Leu Cys Phe Arg Ser Pro Ala Arg Gly Phe Arg Cys Gln Ala Pro Gly 
        35                  40                  45              


Cys Val Leu His Ala Pro Ala Gly Arg Ser Leu Arg Ala Ser Val Leu 
    50                  55                  60                  


Arg Asn Arg Ser Val Leu Leu Gln Trp Arg Leu Ala Pro Ala Ala Ala 
65                  70                  75                  80  


Arg Arg Val Arg Ala Phe Ala Leu Asn Cys Ser Trp Arg Gly Ala Tyr 
                85                  90                  95      


Thr Arg Phe Pro Cys Glu Arg Val Leu Leu Gly Ala Ser Cys Arg Asp 
            100                 105                 110         


Tyr Leu Leu Pro Asp Val His Asp Ser Val Leu Tyr Arg Leu Cys Leu 
        115                 120                 125             


Gln Pro Leu Pro Leu Arg Ala Gly Pro Ala Ala Ala Ala Pro Glu Thr 
    130                 135                 140                 


Pro Glu Pro Ala Glu Cys Val Glu Phe Thr Ala Glu Pro Ala Gly Met 
145                 150                 155                 160 


Gln Asp 
        


<210>  98
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  98

Leu Gln Val Thr Val Pro Asp Lys Lys Lys Val Ala Met Leu Phe Gln 
1               5                   10                  15      


Pro Thr Val Leu Arg Cys His Phe Ser Thr Ser Ser His Gln Pro Ala 
            20                  25                  30          


Val Val Gln Trp Lys Phe Lys Ser Tyr Cys Gln Asp Arg Met Gly Glu 
        35                  40                  45              


Ser Leu Gly Met Ser Ser Thr Arg Ala Gln Ser Leu Ser Lys Arg Asn 
    50                  55                  60                  


Leu Glu Trp Asp Pro Tyr Leu Asp Cys Leu Asp Ser Arg Arg Thr Val 
65                  70                  75                  80  


Arg Val Val Ala Ser Lys Gln Gly Ser Thr Val Thr Leu Gly Asp Phe 
                85                  90                  95      


Tyr Arg Gly Arg Glu Ile Thr Ile Val His Asp Ala Asp Leu Gln Ile 
            100                 105                 110         


Gly Lys Leu Met Trp Gly Asp Ser Gly Leu Tyr Tyr Cys Ile Ile Thr 
        115                 120                 125             


Thr Pro Asp Asp Leu Glu Gly Lys Asn Glu Asp Ser Val Glu Leu Leu 
    130                 135                 140                 


Val Leu Gly Arg Thr Gly Leu Leu Ala Asp Leu Leu Pro Ser Phe Ala 
145                 150                 155                 160 


Val Glu Ile Met Pro Glu 
                165     


<210>  99
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  99

Gly Pro Glu Gly His Tyr Glu Met Leu Gly Thr Cys Arg Met Val Cys 
1               5                   10                  15      


Asp Pro Tyr Pro Ala Arg Gly Pro Gly Ala Gly Ala Arg Thr Asp Gly 
            20                  25                  30          


Gly Asp Ala Leu Ser Glu Gln Ser Gly Ala Pro Pro Pro Ser Thr Leu 
        35                  40                  45              


Val Gln Gly Pro Gln Gly Lys Pro Gly Arg Thr Gly Lys Pro Gly Pro 
    50                  55                  60                  


Pro Gly Pro Pro Gly Asp Pro Gly Pro Pro Gly Pro Val Gly Pro Pro 
65                  70                  75                  80  


Gly Glu Lys Gly Glu Pro Gly Lys Pro Gly Pro Pro Gly Leu Pro Gly 
                85                  90                  95      


Ala Gly Gly Ser Gly Ala Ile Ser Thr Ala Thr Tyr Thr Thr Val Pro 
            100                 105                 110         


Arg Val Ala Phe Tyr Ala Gly Leu Lys Asn Pro His Glu Gly Tyr Glu 
        115                 120                 125             


Val Leu Lys Phe Asp Asp Val Val Thr Asn Leu Gly Asn Asn Tyr Asp 
    130                 135                 140                 


Ala Ala Ser Gly Lys Phe Thr Cys Asn Ile Pro Gly Thr Tyr Phe Phe 
145                 150                 155                 160 


Thr Tyr His Val Leu Met Arg Gly Gly Asp Gly Thr Ser Met Trp Ala 
                165                 170                 175     


Asp Leu Cys Lys Asn Gly Gln Val Arg Ala Ser Ala Ile Ala Gln Asp 
            180                 185                 190         


Ala Asp Gln Asn Tyr Asp Tyr Ala Ser Asn Ser Val Ile Leu His Leu 
        195                 200                 205             


Asp Ala Gly Asp Glu Val Phe Ile Lys Leu Asp Gly Gly Lys Ala His 
    210                 215                 220                 


Gly Gly Asn Ser Asn Lys Tyr Ser Thr Phe Ser Gly Phe Ile Ile Tyr 
225                 230                 235                 240 


Ser Asp 
        


<210>  100
<211>  266
<212>  PRT
<213>  Homo Sapiens

<400>  100

His Tyr Glu Met Met Gly Thr Cys Arg Met Ile Cys Asp Pro Tyr Thr 
1               5                   10                  15      


Ala Ala Pro Gly Gly Glu Pro Pro Gly Ala Lys Ala Gln Pro Pro Gly 
            20                  25                  30          


Pro Ser Thr Ala Ala Leu Glu Val Met Gln Asp Leu Ser Ala Asn Pro 
        35                  40                  45              


Pro Pro Pro Phe Ile Gln Gly Pro Lys Gly Asp Pro Gly Arg Pro Gly 
    50                  55                  60                  


Lys Pro Gly Pro Arg Gly Pro Pro Gly Glu Pro Gly Pro Pro Gly Pro 
65                  70                  75                  80  


Arg Gly Pro Pro Gly Glu Lys Gly Asp Ser Gly Arg Pro Gly Leu Pro 
                85                  90                  95      


Gly Leu Gln Leu Thr Ala Gly Thr Ala Ser Gly Val Gly Val Val Gly 
            100                 105                 110         


Gly Gly Ala Gly Val Gly Gly Asp Ser Glu Gly Glu Val Thr Ser Ala 
        115                 120                 125             


Leu Ser Ala Thr Phe Ser Gly Pro Lys Ile Ala Phe Tyr Val Gly Leu 
    130                 135                 140                 


Lys Ser Pro His Glu Gly Tyr Glu Val Leu Lys Phe Asp Asp Val Val 
145                 150                 155                 160 


Thr Asn Leu Gly Asn His Tyr Asp Pro Thr Thr Gly Lys Phe Ser Cys 
                165                 170                 175     


Gln Val Arg Gly Ile Tyr Phe Phe Thr Tyr His Ile Leu Met Arg Gly 
            180                 185                 190         


Gly Asp Gly Thr Ser Met Trp Ala Asp Leu Cys Lys Asn Gly Gln Val 
        195                 200                 205             


Arg Ala Ser Ala Ile Ala Gln Asp Ala Asp Gln Asn Tyr Asp Tyr Ala 
    210                 215                 220                 


Ser Asn Ser Val Val Leu His Leu Asp Ser Gly Asp Glu Val Tyr Val 
225                 230                 235                 240 


Lys Leu Asp Gly Gly Lys Ala His Gly Gly Asn Asn Asn Lys Tyr Ser 
                245                 250                 255     


Thr Phe Ser Gly Phe Leu Leu Tyr Pro Asp 
            260                 265     


<210>  101
<211>  557
<212>  PRT
<213>  Homo Sapiens

<400>  101

Ala Asp Thr Glu Ala Val Val Cys Val Gly Thr Ala Cys Tyr Thr Ala 
1               5                   10                  15      


His Ser Gly Lys Leu Ser Ala Ala Glu Ala Gln Asn His Cys Asn Gln 
            20                  25                  30          


Asn Gly Gly Asn Leu Ala Thr Val Lys Ser Lys Glu Glu Ala Gln His 
        35                  40                  45              


Val Gln Arg Val Leu Ala Gln Leu Leu Arg Arg Glu Ala Ala Leu Thr 
    50                  55                  60                  


Ala Arg Met Ser Lys Phe Trp Ile Gly Leu Gln Arg Glu Lys Gly Lys 
65                  70                  75                  80  


Cys Leu Asp Pro Ser Leu Pro Leu Lys Gly Phe Ser Trp Val Gly Gly 
                85                  90                  95      


Gly Glu Asp Thr Pro Tyr Ser Asn Trp His Lys Glu Leu Arg Asn Ser 
            100                 105                 110         


Cys Ile Ser Lys Arg Cys Val Ser Leu Leu Leu Asp Leu Ser Gln Pro 
        115                 120                 125             


Leu Leu Pro Ser Arg Leu Pro Lys Trp Ser Glu Gly Pro Cys Gly Ser 
    130                 135                 140                 


Pro Gly Ser Pro Gly Ser Asn Ile Glu Gly Phe Val Cys Lys Phe Ser 
145                 150                 155                 160 


Phe Lys Gly Met Cys Arg Pro Leu Ala Leu Gly Gly Pro Gly Gln Val 
                165                 170                 175     


Thr Tyr Thr Thr Pro Phe Gln Thr Thr Ser Ser Ser Leu Glu Ala Val 
            180                 185                 190         


Pro Phe Ala Ser Ala Ala Asn Val Ala Cys Gly Glu Gly Asp Lys Asp 
        195                 200                 205             


Glu Thr Gln Ser His Tyr Phe Leu Cys Lys Glu Lys Ala Pro Asp Val 
    210                 215                 220                 


Phe Asp Trp Gly Ser Ser Gly Pro Leu Cys Val Ser Pro Lys Tyr Gly 
225                 230                 235                 240 


Cys Asn Phe Asn Asn Gly Gly Cys His Gln Asp Cys Phe Glu Gly Gly 
                245                 250                 255     


Asp Gly Ser Phe Leu Cys Gly Cys Arg Pro Gly Phe Arg Leu Leu Asp 
            260                 265                 270         


Asp Leu Val Thr Cys Ala Ser Arg Asn Pro Cys Ser Ser Ser Pro Cys 
        275                 280                 285             


Arg Gly Gly Ala Thr Cys Val Leu Gly Pro His Gly Lys Asn Tyr Thr 
    290                 295                 300                 


Cys Arg Cys Pro Gln Gly Tyr Gln Leu Asp Ser Ser Gln Leu Asp Cys 
305                 310                 315                 320 


Val Asp Val Asp Glu Cys Gln Asp Ser Pro Cys Ala Gln Glu Cys Val 
                325                 330                 335     


Asn Thr Pro Gly Gly Phe Arg Cys Glu Cys Trp Val Gly Tyr Glu Pro 
            340                 345                 350         


Gly Gly Pro Gly Glu Gly Ala Cys Gln Asp Val Asp Glu Cys Ala Leu 
        355                 360                 365             


Gly Arg Ser Pro Cys Ala Gln Gly Cys Thr Asn Thr Asp Gly Ser Phe 
    370                 375                 380                 


His Cys Ser Cys Glu Glu Gly Tyr Val Leu Ala Gly Glu Asp Gly Thr 
385                 390                 395                 400 


Gln Cys Gln Asp Val Asp Glu Cys Val Gly Pro Gly Gly Pro Leu Cys 
                405                 410                 415     


Asp Ser Leu Cys Phe Asn Thr Gln Gly Ser Phe His Cys Gly Cys Leu 
            420                 425                 430         


Pro Gly Trp Val Leu Ala Pro Asn Gly Val Ser Cys Thr Met Gly Pro 
        435                 440                 445             


Val Ser Leu Gly Pro Pro Ser Gly Pro Pro Asp Glu Glu Asp Lys Gly 
    450                 455                 460                 


Glu Lys Glu Gly Ser Thr Val Pro Arg Ala Ala Thr Ala Ser Pro Thr 
465                 470                 475                 480 


Arg Gly Pro Glu Gly Thr Pro Lys Ala Thr Pro Thr Thr Ser Arg Pro 
                485                 490                 495     


Ser Leu Ser Ser Asp Ala Pro Ile Thr Ser Ala Pro Leu Lys Met Leu 
            500                 505                 510         


Ala Pro Ser Gly Ser Pro Gly Val Trp Arg Glu Pro Ser Ile His His 
        515                 520                 525             


Ala Thr Ala Ala Ser Gly Pro Gln Glu Pro Ala Gly Gly Asp Ser Ser 
    530                 535                 540                 


Val Ala Thr Gln Asn Asn Asp Gly Thr Asp Gly Gln Lys 
545                 550                 555         


<210>  102
<211>  270
<212>  PRT
<213>  Homo Sapiens

<400>  102

Asp Pro Leu Leu Gly Ala Phe Ala Arg Arg Asp Phe Arg Lys Gly Ser 
1               5                   10                  15      


Pro Gln Leu Val Cys Ser Leu Pro Gly Pro Gln Gly Pro Pro Gly Pro 
            20                  25                  30          


Pro Gly Ala Pro Gly Pro Ser Gly Met Met Gly Arg Met Gly Phe Pro 
        35                  40                  45              


Gly Lys Asp Gly Gln Asp Gly His Asp Gly Asp Arg Gly Asp Ser Gly 
    50                  55                  60                  


Glu Glu Gly Pro Pro Gly Arg Thr Gly Asn Arg Gly Lys Pro Gly Pro 
65                  70                  75                  80  


Lys Gly Lys Ala Gly Ala Ile Gly Arg Ala Gly Pro Arg Gly Pro Lys 
                85                  90                  95      


Gly Val Asn Gly Thr Pro Gly Lys His Gly Thr Pro Gly Lys Lys Gly 
            100                 105                 110         


Pro Lys Gly Lys Lys Gly Glu Pro Gly Leu Pro Gly Pro Cys Ser Cys 
        115                 120                 125             


Gly Ser Gly His Thr Lys Ser Ala Phe Ser Val Ala Val Thr Lys Ser 
    130                 135                 140                 


Tyr Pro Arg Glu Arg Leu Pro Ile Lys Phe Asp Lys Ile Leu Met Asn 
145                 150                 155                 160 


Glu Gly Gly His Tyr Asn Ala Ser Ser Gly Lys Phe Val Cys Gly Val 
                165                 170                 175     


Pro Gly Ile Tyr Tyr Phe Thr Tyr Asp Ile Thr Leu Ala Asn Lys His 
            180                 185                 190         


Leu Ala Ile Gly Leu Val His Asn Gly Gln Tyr Arg Ile Arg Thr Phe 
        195                 200                 205             


Asp Ala Asn Thr Gly Asn His Asp Val Ala Ser Gly Ser Thr Ile Leu 
    210                 215                 220                 


Ala Leu Lys Gln Gly Asp Glu Val Trp Leu Gln Ile Phe Tyr Ser Glu 
225                 230                 235                 240 


Gln Asn Gly Leu Phe Tyr Asp Pro Tyr Trp Thr Asp Ser Leu Phe Thr 
                245                 250                 255     


Gly Phe Leu Ile Tyr Ala Asp Gln Asp Asp Pro Asn Glu Val 
            260                 265                 270 


<210>  103
<211>  313
<212>  PRT
<213>  Homo Sapiens

<400>  103

Leu Gly Pro Thr Pro Gly Pro Gly Ser Ser Glu Leu Arg Ser Ala Phe 
1               5                   10                  15      


Ser Ala Ala Arg Thr Thr Pro Leu Glu Gly Thr Ser Glu Met Ala Val 
            20                  25                  30          


Thr Phe Asp Lys Val Tyr Val Asn Ile Gly Gly Asp Phe Asp Val Ala 
        35                  40                  45              


Thr Gly Gln Phe Arg Cys Arg Val Pro Gly Ala Tyr Phe Phe Ser Phe 
    50                  55                  60                  


Thr Ala Gly Lys Ala Pro His Lys Ser Leu Ser Val Met Leu Val Arg 
65                  70                  75                  80  


Asn Arg Asp Glu Val Gln Ala Leu Ala Phe Asp Glu Gln Arg Arg Pro 
                85                  90                  95      


Gly Ala Arg Arg Ala Ala Ser Gln Ser Ala Met Leu Gln Leu Asp Tyr 
            100                 105                 110         


Gly Asp Thr Val Trp Leu Arg Leu His Gly Ala Pro Gln Tyr Ala Leu 
        115                 120                 125             


Gly Ala Pro Gly Ala Thr Phe Ser Gly Tyr Leu Val Tyr Ala Asp Ala 
    130                 135                 140                 


Asp Ala Asp Ala Pro Ala Arg Gly Pro Pro Ala Pro Pro Glu Pro Arg 
145                 150                 155                 160 


Ser Ala Phe Ser Ala Ala Arg Thr Arg Ser Leu Val Gly Ser Asp Ala 
                165                 170                 175     


Gly Pro Gly Pro Arg His Gln Pro Leu Ala Phe Asp Thr Glu Phe Val 
            180                 185                 190         


Asn Ile Gly Gly Asp Phe Asp Ala Ala Ala Gly Val Phe Arg Cys Arg 
        195                 200                 205             


Leu Pro Gly Ala Tyr Phe Phe Ser Phe Thr Leu Gly Lys Leu Pro Arg 
    210                 215                 220                 


Lys Thr Leu Ser Val Lys Leu Met Lys Asn Arg Asp Glu Val Gln Ala 
225                 230                 235                 240 


Met Ile Tyr Asp Asp Gly Ala Ser Arg Arg Arg Glu Met Gln Ser Gln 
                245                 250                 255     


Ser Val Met Leu Ala Leu Arg Arg Gly Asp Ala Val Trp Leu Leu Ser 
            260                 265                 270         


His Asp His Asp Gly Tyr Gly Ala Tyr Ser Asn His Gly Lys Tyr Ile 
        275                 280                 285             


Thr Phe Ser Gly Phe Leu Val Tyr Pro Asp Leu Ala Pro Ala Ala Pro 
    290                 295                 300                 


Pro Gly Leu Gly Ala Ser Glu Leu Leu 
305                 310             


<210>  104
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  104

Ser Pro Pro Leu Asp Asp Asn Lys Ile Pro Ser Leu Cys Pro Gly His 
1               5                   10                  15      


Pro Gly Leu Pro Gly Thr Pro Gly His His Gly Ser Arg Gly Leu Pro 
            20                  25                  30          


Gly Arg Asp Gly Arg Asp Gly Arg Asp Gly Ala Pro Gly Ala Pro Gly 
        35                  40                  45              


Glu Lys Gly Glu Gly Gly Arg Pro Gly Leu Pro Gly Pro Arg Gly Asp 
    50                  55                  60                  


Pro Gly Pro Arg Gly Glu Ala Gly Pro Ala Gly Pro Thr Gly Pro Ala 
65                  70                  75                  80  


Gly Glu Cys Ser Val Pro Pro Arg Ser Ala Phe Ser Ala Lys Arg Ser 
                85                  90                  95      


Glu Ser Arg Val Pro Pro Pro Ser Asp Ala Pro Leu Pro Phe Asp Arg 
            100                 105                 110         


Val Leu Val Asn Glu Gln Gly His Tyr Asp Ala Val Thr Gly Lys Phe 
        115                 120                 125             


Thr Cys Gln Val Pro Gly Val Tyr Tyr Phe Ala Val His Ala Thr Val 
    130                 135                 140                 


Tyr Arg Ala Ser Leu Gln Phe Asp Leu Val Lys Asn Gly Glu Ser Ile 
145                 150                 155                 160 


Ala Ser Phe Phe Gln Phe Phe Gly Gly Trp Pro Lys Pro Ala Ser Leu 
                165                 170                 175     


Ser Gly Gly Ala Met Val Arg Leu Glu Pro Glu Asp Gln Val Trp Val 
            180                 185                 190         


Gln Val Gly Val Gly Asp Tyr Ile Gly Ile Tyr Ala Ser Ile Lys Thr 
        195                 200                 205             


Asp Ser Thr Phe Ser Gly Phe Leu Val Tyr Ser Asp Trp His Ser Ser 
    210                 215                 220                 


Pro Val Phe Ala 
225             


<210>  105
<211>  688
<212>  PRT
<213>  Homo Sapiens

<400>  105

Ser Ile Pro Ile Pro Gln Lys Leu Phe Gly Glu Val Thr Ser Pro Leu 
1               5                   10                  15      


Phe Pro Lys Pro Tyr Pro Asn Asn Phe Glu Thr Thr Thr Val Ile Thr 
            20                  25                  30          


Val Pro Thr Gly Tyr Arg Val Lys Leu Val Phe Gln Gln Phe Asp Leu 
        35                  40                  45              


Glu Pro Ser Glu Gly Cys Phe Tyr Asp Tyr Val Lys Ile Ser Ala Asp 
    50                  55                  60                  


Lys Lys Ser Leu Gly Arg Phe Cys Gly Gln Leu Gly Ser Pro Leu Gly 
65                  70                  75                  80  


Asn Pro Pro Gly Lys Lys Glu Phe Met Ser Gln Gly Asn Lys Met Leu 
                85                  90                  95      


Leu Thr Phe His Thr Asp Phe Ser Asn Glu Glu Asn Gly Thr Ile Met 
            100                 105                 110         


Phe Tyr Lys Gly Phe Leu Ala Tyr Tyr Gln Ala Val Asp Leu Asp Glu 
        115                 120                 125             


Cys Ala Ser Arg Ser Lys Leu Gly Glu Glu Asp Pro Gln Pro Gln Cys 
    130                 135                 140                 


Gln His Leu Cys His Asn Tyr Val Gly Gly Tyr Phe Cys Ser Cys Arg 
145                 150                 155                 160 


Pro Gly Tyr Glu Leu Gln Glu Asp Arg His Ser Cys Gln Ala Glu Cys 
                165                 170                 175     


Ser Ser Glu Leu Tyr Thr Glu Ala Ser Gly Tyr Ile Ser Ser Leu Glu 
            180                 185                 190         


Tyr Pro Arg Ser Tyr Pro Pro Asp Leu Arg Cys Asn Tyr Ser Ile Arg 
        195                 200                 205             


Val Glu Arg Gly Leu Thr Leu His Leu Lys Phe Leu Glu Pro Phe Asp 
    210                 215                 220                 


Ile Asp Asp His Gln Gln Val His Cys Pro Tyr Asp Gln Leu Gln Ile 
225                 230                 235                 240 


Tyr Ala Asn Gly Lys Asn Ile Gly Glu Phe Cys Gly Lys Gln Arg Pro 
                245                 250                 255     


Pro Asp Leu Asp Thr Ser Ser Asn Ala Val Asp Leu Leu Phe Phe Thr 
            260                 265                 270         


Asp Glu Ser Gly Asp Ser Arg Gly Trp Lys Leu Arg Tyr Thr Thr Glu 
        275                 280                 285             


Ile Ile Lys Cys Pro Gln Pro Lys Thr Leu Asp Glu Phe Thr Ile Ile 
    290                 295                 300                 


Gln Asn Leu Gln Pro Gln Tyr Gln Phe Arg Asp Tyr Phe Ile Ala Thr 
305                 310                 315                 320 


Cys Lys Gln Gly Tyr Gln Leu Ile Glu Gly Asn Gln Val Leu His Ser 
                325                 330                 335     


Phe Thr Ala Val Cys Gln Asp Asp Gly Thr Trp His Arg Ala Met Pro 
            340                 345                 350         


Arg Cys Lys Ile Lys Asp Cys Gly Gln Pro Arg Asn Leu Pro Asn Gly 
        355                 360                 365             


Asp Phe Arg Tyr Thr Thr Thr Met Gly Val Asn Thr Tyr Lys Ala Arg 
    370                 375                 380                 


Ile Gln Tyr Tyr Cys His Glu Pro Tyr Tyr Lys Met Gln Thr Arg Ala 
385                 390                 395                 400 


Gly Ser Arg Glu Ser Glu Gln Gly Val Tyr Thr Cys Thr Ala Gln Gly 
                405                 410                 415     


Ile Trp Lys Asn Glu Gln Lys Gly Glu Lys Ile Pro Arg Cys Leu Pro 
            420                 425                 430         


Val Cys Gly Lys Pro Val Asn Pro Val Glu Gln Arg Gln Arg Ile Ile 
        435                 440                 445             


Gly Gly Gln Lys Ala Lys Met Gly Asn Phe Pro Trp Gln Val Phe Thr 
    450                 455                 460                 


Asn Ile His Gly Arg Gly Gly Gly Ala Leu Leu Gly Asp Arg Trp Ile 
465                 470                 475                 480 


Leu Thr Ala Ala His Thr Leu Tyr Pro Lys Glu His Glu Ala Gln Ser 
                485                 490                 495     


Asn Ala Ser Leu Asp Val Phe Leu Gly His Thr Asn Val Glu Glu Leu 
            500                 505                 510         


Met Lys Leu Gly Asn His Pro Ile Arg Arg Val Ser Val His Pro Asp 
        515                 520                 525             


Tyr Arg Gln Asp Glu Ser Tyr Asn Phe Glu Gly Asp Ile Ala Leu Leu 
    530                 535                 540                 


Glu Leu Glu Asn Ser Val Thr Leu Gly Pro Asn Leu Leu Pro Ile Cys 
545                 550                 555                 560 


Leu Pro Asp Asn Asp Thr Phe Tyr Asp Leu Gly Leu Met Gly Tyr Val 
                565                 570                 575     


Ser Gly Phe Gly Val Met Glu Glu Lys Ile Ala His Asp Leu Arg Phe 
            580                 585                 590         


Val Arg Leu Pro Val Ala Asn Pro Gln Ala Cys Glu Asn Trp Leu Arg 
        595                 600                 605             


Gly Lys Asn Arg Met Asp Val Phe Ser Gln Asn Met Phe Cys Ala Gly 
    610                 615                 620                 


His Pro Ser Leu Lys Gln Asp Ala Cys Gln Gly Asp Ser Gly Gly Val 
625                 630                 635                 640 


Phe Ala Val Arg Asp Pro Asn Thr Asp Arg Trp Val Ala Thr Gly Ile 
                645                 650                 655     


Val Ser Trp Gly Ile Gly Cys Ser Arg Gly Tyr Gly Phe Tyr Thr Lys 
            660                 665                 670         


Val Leu Asn Tyr Val Asp Trp Ile Lys Lys Glu Met Glu Glu Glu Asp 
        675                 680                 685             


<210>  106
<211>  673
<212>  PRT
<213>  Homo Sapiens

<400>  106

Glu Pro Thr Met Tyr Gly Glu Ile Leu Ser Pro Asn Tyr Pro Gln Ala 
1               5                   10                  15      


Tyr Pro Ser Glu Val Glu Lys Ser Trp Asp Ile Glu Val Pro Glu Gly 
            20                  25                  30          


Tyr Gly Ile His Leu Tyr Phe Thr His Leu Asp Ile Glu Leu Ser Glu 
        35                  40                  45              


Asn Cys Ala Tyr Asp Ser Val Gln Ile Ile Ser Gly Asp Thr Glu Glu 
    50                  55                  60                  


Gly Arg Leu Cys Gly Gln Arg Ser Ser Asn Asn Pro His Ser Pro Ile 
65                  70                  75                  80  


Val Glu Glu Phe Gln Val Pro Tyr Asn Lys Leu Gln Val Ile Phe Lys 
                85                  90                  95      


Ser Asp Phe Ser Asn Glu Glu Arg Phe Thr Gly Phe Ala Ala Tyr Tyr 
            100                 105                 110         


Val Ala Thr Asp Ile Asn Glu Cys Thr Asp Phe Val Asp Val Pro Cys 
        115                 120                 125             


Ser His Phe Cys Asn Asn Phe Ile Gly Gly Tyr Phe Cys Ser Cys Pro 
    130                 135                 140                 


Pro Glu Tyr Phe Leu His Asp Asp Met Lys Asn Cys Gly Val Asn Cys 
145                 150                 155                 160 


Ser Gly Asp Val Phe Thr Ala Leu Ile Gly Glu Ile Ala Ser Pro Asn 
                165                 170                 175     


Tyr Pro Lys Pro Tyr Pro Glu Asn Ser Arg Cys Glu Tyr Gln Ile Arg 
            180                 185                 190         


Leu Glu Lys Gly Phe Gln Val Val Val Thr Leu Arg Arg Glu Asp Phe 
        195                 200                 205             


Asp Val Glu Ala Ala Asp Ser Ala Gly Asn Cys Leu Asp Ser Leu Val 
    210                 215                 220                 


Phe Val Ala Gly Asp Arg Gln Phe Gly Pro Tyr Cys Gly His Gly Phe 
225                 230                 235                 240 


Pro Gly Pro Leu Asn Ile Glu Thr Lys Ser Asn Ala Leu Asp Ile Ile 
                245                 250                 255     


Phe Gln Thr Asp Leu Thr Gly Gln Lys Lys Gly Trp Lys Leu Arg Tyr 
            260                 265                 270         


His Gly Asp Pro Met Pro Cys Pro Lys Glu Asp Thr Pro Asn Ser Val 
        275                 280                 285             


Trp Glu Pro Ala Lys Ala Lys Tyr Val Phe Arg Asp Val Val Gln Ile 
    290                 295                 300                 


Thr Cys Leu Asp Gly Phe Glu Val Val Glu Gly Arg Val Gly Ala Thr 
305                 310                 315                 320 


Ser Phe Tyr Ser Thr Cys Gln Ser Asn Gly Lys Trp Ser Asn Ser Lys 
                325                 330                 335     


Leu Lys Cys Gln Pro Val Asp Cys Gly Ile Pro Glu Ser Ile Glu Asn 
            340                 345                 350         


Gly Lys Val Glu Asp Pro Glu Ser Thr Leu Phe Gly Ser Val Ile Arg 
        355                 360                 365             


Tyr Thr Cys Glu Glu Pro Tyr Tyr Tyr Met Glu Asn Gly Gly Gly Gly 
    370                 375                 380                 


Glu Tyr His Cys Ala Gly Asn Gly Ser Trp Val Asn Glu Val Leu Gly 
385                 390                 395                 400 


Pro Glu Leu Pro Lys Cys Val Pro Val Cys Gly Val Pro Arg Glu Pro 
                405                 410                 415     


Phe Glu Glu Lys Gln Arg Ile Ile Gly Gly Ser Asp Ala Asp Ile Lys 
            420                 425                 430         


Asn Phe Pro Trp Gln Val Phe Phe Asp Asn Pro Trp Ala Gly Gly Ala 
        435                 440                 445             


Leu Ile Asn Glu Tyr Trp Val Leu Thr Ala Ala His Val Val Glu Gly 
    450                 455                 460                 


Asn Arg Glu Pro Thr Met Tyr Val Gly Ser Thr Ser Val Gln Thr Ser 
465                 470                 475                 480 


Arg Leu Ala Lys Ser Lys Met Leu Thr Pro Glu His Val Phe Ile His 
                485                 490                 495     


Pro Gly Trp Lys Leu Leu Glu Val Pro Glu Gly Arg Thr Asn Phe Asp 
            500                 505                 510         


Asn Asp Ile Ala Leu Val Arg Leu Lys Asp Pro Val Lys Met Gly Pro 
        515                 520                 525             


Thr Val Ser Pro Ile Cys Leu Pro Gly Thr Ser Ser Asp Tyr Asn Leu 
    530                 535                 540                 


Met Asp Gly Asp Leu Gly Leu Ile Ser Gly Trp Gly Arg Thr Glu Lys 
545                 550                 555                 560 


Arg Asp Arg Ala Val Arg Leu Lys Ala Ala Arg Leu Pro Val Ala Pro 
                565                 570                 575     


Leu Arg Lys Cys Lys Glu Val Lys Val Glu Lys Pro Thr Ala Asp Ala 
            580                 585                 590         


Glu Ala Tyr Val Phe Thr Pro Asn Met Ile Cys Ala Gly Gly Glu Lys 
        595                 600                 605             


Gly Met Asp Ser Cys Lys Gly Asp Ser Gly Gly Ala Phe Ala Val Gln 
    610                 615                 620                 


Asp Pro Asn Asp Lys Thr Lys Phe Tyr Ala Ala Gly Leu Val Ser Trp 
625                 630                 635                 640 


Gly Pro Gln Cys Gly Thr Tyr Gly Leu Tyr Thr Arg Val Lys Asn Tyr 
                645                 650                 655     


Val Asp Trp Ile Met Lys Thr Met Gln Glu Asn Ser Thr Pro Arg Glu 
            660                 665                 670         


Asp 
    


<210>  107
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  107

Ser Val Gln Leu Thr Glu Lys Arg Met Asp Lys Val Gly Lys Tyr Pro 
1               5                   10                  15      


Lys Glu Leu Arg Lys Cys Cys Glu Asp Gly Met Arg Glu Asn Pro Met 
            20                  25                  30          


Arg Phe Ser Cys Gln Arg Arg Thr Arg Phe Ile Ser Leu Gly Glu Ala 
        35                  40                  45              


Cys Lys Lys Val Phe Leu Asp Cys Cys Asn Tyr Ile Thr Glu Leu Arg 
    50                  55                  60                  


Arg Gln His Ala Arg Ala Ser His Leu Gly Leu Ala Arg 
65                  70                  75          


<210>  108
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  108

Asn Val Asn Phe Gln Lys Ala Ile Asn Glu Lys Leu Gly Gln Tyr Ala 
1               5                   10                  15      


Ser Pro Thr Ala Lys Arg Cys Cys Gln Asp Gly Val Thr Arg Leu Pro 
            20                  25                  30          


Met Met Arg Ser Cys Glu Gln Arg Ala Ala Arg Val Gln Gln Pro Asp 
        35                  40                  45              


Cys Trp Glu Pro Phe Leu Ser Cys Cys Gln Phe Ala Glu Ser Leu Arg 
    50                  55                  60                  


Lys Lys Ser Arg Asp Lys Gly Gln Ala Gly Leu Gln Arg 
65                  70                  75          


<210>  109
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  109

Thr Leu Gln Lys Lys Ile Glu Glu Ile Ala Ala Lys Tyr Lys His Ser 
1               5                   10                  15      


Val Val Lys Lys Cys Cys Tyr Asp Gly Ala Cys Val Asn Asn Asp Glu 
            20                  25                  30          


Thr Cys Glu Gln Arg Ala Ala Arg Ile Ser Leu Gly Pro Arg Cys Ile 
        35                  40                  45              


Lys Ala Phe Thr Glu Cys Cys Val Val Ala Ser Gln Leu Arg Ala Asn 
    50                  55                  60                  


Ile Ser His Lys Asp Met Gln Leu Gly Arg 
65                  70                  


<210>  110
<211>  913
<212>  PRT
<213>  Homo Sapiens

<400>  110

Cys Phe Cys Asp His Tyr Ala Trp Thr Gln Trp Thr Ser Cys Ser Lys 
1               5                   10                  15      


Thr Cys Asn Ser Gly Thr Gln Ser Arg His Arg Gln Ile Val Val Asp 
            20                  25                  30          


Lys Tyr Tyr Gln Glu Asn Phe Cys Glu Gln Ile Cys Ser Lys Gln Glu 
        35                  40                  45              


Thr Arg Glu Cys Asn Trp Gln Arg Cys Pro Ile Asn Cys Leu Leu Gly 
    50                  55                  60                  


Asp Phe Gly Pro Trp Ser Asp Cys Asp Pro Cys Ile Glu Lys Gln Ser 
65                  70                  75                  80  


Lys Val Arg Ser Val Leu Arg Pro Ser Gln Phe Gly Gly Gln Pro Cys 
                85                  90                  95      


Thr Glu Pro Leu Val Ala Phe Gln Pro Cys Ile Pro Ser Lys Leu Cys 
            100                 105                 110         


Lys Ile Glu Glu Ala Asp Cys Lys Asn Lys Phe Arg Cys Asp Ser Gly 
        115                 120                 125             


Arg Cys Ile Ala Arg Lys Leu Glu Cys Asn Gly Glu Asn Asp Cys Gly 
    130                 135                 140                 


Asp Asn Ser Asp Glu Arg Asp Cys Gly Arg Thr Lys Ala Val Cys Thr 
145                 150                 155                 160 


Arg Lys Tyr Asn Pro Ile Pro Ser Val Gln Leu Met Gly Asn Gly Phe 
                165                 170                 175     


His Phe Leu Ala Gly Glu Pro Arg Gly Glu Val Leu Asp Asn Ser Phe 
            180                 185                 190         


Thr Gly Gly Ile Cys Lys Thr Val Lys Ser Ser Arg Thr Ser Asn Pro 
        195                 200                 205             


Tyr Arg Val Pro Ala Asn Leu Glu Asn Val Gly Phe Glu Val Gln Thr 
    210                 215                 220                 


Ala Glu Asp Asp Leu Lys Thr Asp Phe Tyr Lys Asp Leu Thr Ser Leu 
225                 230                 235                 240 


Gly His Asn Glu Asn Gln Gln Gly Ser Phe Ser Ser Gln Gly Gly Ser 
                245                 250                 255     


Ser Phe Ser Val Pro Ile Phe Tyr Ser Ser Lys Arg Ser Glu Asn Ile 
            260                 265                 270         


Asn His Asn Ser Ala Phe Lys Gln Ala Ile Gln Ala Ser His Lys Lys 
        275                 280                 285             


Asp Ser Ser Phe Ile Arg Ile His Lys Val Met Lys Val Leu Asn Phe 
    290                 295                 300                 


Thr Thr Lys Ala Lys Asp Leu His Leu Ser Asp Val Phe Leu Lys Ala 
305                 310                 315                 320 


Leu Asn His Leu Pro Leu Glu Tyr Asn Ser Ala Leu Tyr Ser Arg Ile 
                325                 330                 335     


Phe Asp Asp Phe Gly Thr His Tyr Phe Thr Ser Gly Ser Leu Gly Gly 
            340                 345                 350         


Val Tyr Asp Leu Leu Tyr Gln Phe Ser Ser Glu Glu Leu Lys Asn Ser 
        355                 360                 365             


Gly Leu Thr Glu Glu Glu Ala Lys His Cys Val Arg Ile Glu Thr Lys 
    370                 375                 380                 


Lys Arg Val Leu Phe Ala Lys Lys Thr Lys Val Glu His Arg Cys Thr 
385                 390                 395                 400 


Thr Asn Lys Leu Ser Glu Lys His Glu Gly Ser Phe Ile Gln Gly Ala 
                405                 410                 415     


Glu Lys Ser Ile Ser Leu Ile Arg Gly Gly Arg Ser Glu Tyr Gly Ala 
            420                 425                 430         


Ala Leu Ala Trp Glu Lys Gly Ser Ser Gly Leu Glu Glu Lys Thr Phe 
        435                 440                 445             


Ser Glu Trp Leu Glu Ser Val Lys Glu Asn Pro Ala Val Ile Asp Phe 
    450                 455                 460                 


Glu Leu Ala Pro Ile Val Asp Leu Val Arg Asn Ile Pro Cys Ala Val 
465                 470                 475                 480 


Thr Lys Arg Asn Asn Leu Arg Lys Ala Leu Gln Glu Tyr Ala Ala Lys 
                485                 490                 495     


Phe Asp Pro Cys Gln Cys Ala Pro Cys Pro Asn Asn Gly Arg Pro Thr 
            500                 505                 510         


Leu Ser Gly Thr Glu Cys Leu Cys Val Cys Gln Ser Gly Thr Tyr Gly 
        515                 520                 525             


Glu Asn Cys Glu Lys Gln Ser Pro Asp Tyr Lys Ser Asn Ala Val Asp 
    530                 535                 540                 


Gly Gln Trp Gly Cys Trp Ser Ser Trp Ser Thr Cys Asp Ala Thr Tyr 
545                 550                 555                 560 


Lys Arg Ser Arg Thr Arg Glu Cys Asn Asn Pro Ala Pro Gln Arg Gly 
                565                 570                 575     


Gly Lys Arg Cys Glu Gly Glu Lys Arg Gln Glu Glu Asp Cys Thr Phe 
            580                 585                 590         


Ser Ile Met Glu Asn Asn Gly Gln Pro Cys Ile Asn Asp Asp Glu Glu 
        595                 600                 605             


Met Lys Glu Val Asp Leu Pro Glu Ile Glu Ala Asp Ser Gly Cys Pro 
    610                 615                 620                 


Gln Pro Val Pro Pro Glu Asn Gly Phe Ile Arg Asn Glu Lys Gln Leu 
625                 630                 635                 640 


Tyr Leu Val Gly Glu Asp Val Glu Ile Ser Cys Leu Thr Gly Phe Glu 
                645                 650                 655     


Thr Val Gly Tyr Gln Tyr Phe Arg Cys Leu Pro Asp Gly Thr Trp Arg 
            660                 665                 670         


Gln Gly Asp Val Glu Cys Gln Arg Thr Glu Cys Ile Lys Pro Val Val 
        675                 680                 685             


Gln Glu Val Leu Thr Ile Thr Pro Phe Gln Arg Leu Tyr Arg Ile Gly 
    690                 695                 700                 


Glu Ser Ile Glu Leu Thr Cys Pro Lys Gly Phe Val Val Ala Gly Pro 
705                 710                 715                 720 


Ser Arg Tyr Thr Cys Gln Gly Asn Ser Trp Thr Pro Pro Ile Ser Asn 
                725                 730                 735     


Ser Leu Thr Cys Glu Lys Asp Thr Leu Thr Lys Leu Lys Gly His Cys 
            740                 745                 750         


Gln Leu Gly Gln Lys Gln Ser Gly Ser Glu Cys Ile Cys Met Ser Pro 
        755                 760                 765             


Glu Glu Asp Cys Ser His His Ser Glu Asp Leu Cys Val Phe Asp Thr 
    770                 775                 780                 


Asp Ser Asn Asp Tyr Phe Thr Ser Pro Ala Cys Lys Phe Leu Ala Glu 
785                 790                 795                 800 


Lys Cys Leu Asn Asn Gln Gln Leu His Phe Leu His Ile Gly Ser Cys 
                805                 810                 815     


Gln Asp Gly Arg Gln Leu Glu Trp Gly Leu Glu Arg Thr Arg Leu Ser 
            820                 825                 830         


Ser Asn Ser Thr Lys Lys Glu Ser Cys Gly Tyr Asp Thr Cys Tyr Asp 
        835                 840                 845             


Trp Glu Lys Cys Ser Ala Ser Thr Ser Lys Cys Val Cys Leu Leu Pro 
    850                 855                 860                 


Pro Gln Cys Phe Lys Gly Gly Asn Gln Leu Tyr Cys Val Lys Met Gly 
865                 870                 875                 880 


Ser Ser Thr Ser Glu Lys Thr Leu Asn Ile Cys Glu Val Gly Thr Ile 
                885                 890                 895     


Arg Cys Ala Asn Arg Lys Met Glu Ile Leu His Pro Gly Lys Cys Leu 
            900                 905                 910         


Ala 
    


<210>  111
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  111

Asn Pro Gly Ala Ser Leu Asp Gly Arg Pro Gly Asp Arg Val Asn Leu 
1               5                   10                  15      


Ser Cys Gly Gly Val Ser His Pro Ile Arg Trp Val Trp Ala Pro Ser 
            20                  25                  30          


Phe Pro Ala Cys Lys Gly Leu Ser Lys Gly Arg Arg Pro Ile Leu Trp 
        35                  40                  45              


Ala Ser Ser Ser Gly Thr Pro Thr Val Pro Pro Leu Gln Pro Phe Val 
    50                  55                  60                  


Gly Arg Leu Arg Ser Leu Asp Ser Gly Ile Arg Arg Leu Glu Leu Leu 
65                  70                  75                  80  


Leu Ser Ala Gly Asp Ser Gly Thr Phe Phe Cys Lys Gly Arg His Glu 
                85                  90                  95      


Asp Glu Ser Arg Thr Val Leu His Val Leu Gly Asp Arg Thr Tyr Cys 
            100                 105                 110         


Lys Ala Pro Gly Pro Thr His Gly Ser Val Tyr Pro Gln 
        115                 120                 125 


<210>  112
<211>  821
<212>  PRT
<213>  Homo Sapiens

<400>  112

Ser Ser Pro Val Asn Cys Gln Trp Asp Phe Tyr Ala Pro Trp Ser Glu 
1               5                   10                  15      


Cys Asn Gly Cys Thr Lys Thr Gln Thr Arg Arg Arg Ser Val Ala Val 
            20                  25                  30          


Tyr Gly Gln Tyr Gly Gly Gln Pro Cys Val Gly Asn Ala Phe Glu Thr 
        35                  40                  45              


Gln Ser Cys Glu Pro Thr Arg Gly Cys Pro Thr Glu Glu Gly Cys Gly 
    50                  55                  60                  


Glu Arg Phe Arg Cys Phe Ser Gly Gln Cys Ile Ser Lys Ser Leu Val 
65                  70                  75                  80  


Cys Asn Gly Asp Ser Asp Cys Asp Glu Asp Ser Ala Asp Glu Asp Arg 
                85                  90                  95      


Cys Glu Asp Ser Glu Arg Arg Pro Ser Cys Asp Ile Asp Lys Pro Pro 
            100                 105                 110         


Pro Asn Ile Glu Leu Thr Gly Asn Gly Tyr Asn Glu Leu Thr Gly Gln 
        115                 120                 125             


Phe Arg Asn Arg Val Ile Asn Thr Lys Ser Phe Gly Gly Gln Cys Arg 
    130                 135                 140                 


Lys Val Phe Ser Gly Asp Gly Lys Asp Phe Tyr Arg Leu Ser Gly Asn 
145                 150                 155                 160 


Val Leu Ser Tyr Thr Phe Gln Val Lys Ile Asn Asn Asp Phe Asn Tyr 
                165                 170                 175     


Glu Phe Tyr Asn Ser Thr Trp Ser Tyr Val Lys His Thr Ser Thr Glu 
            180                 185                 190         


His Thr Ser Ser Ser Arg Lys Arg Ser Phe Phe Arg Ser Ser Ser Ser 
        195                 200                 205             


Ser Ser Arg Ser Tyr Thr Ser His Thr Asn Glu Ile His Lys Gly Lys 
    210                 215                 220                 


Ser Tyr Gln Leu Leu Val Val Glu Asn Thr Val Glu Val Ala Gln Phe 
225                 230                 235                 240 


Ile Asn Asn Asn Pro Glu Phe Leu Gln Leu Ala Glu Pro Phe Trp Lys 
                245                 250                 255     


Glu Leu Ser His Leu Pro Ser Leu Tyr Asp Tyr Ser Ala Tyr Arg Arg 
            260                 265                 270         


Leu Ile Asp Gln Tyr Gly Thr His Tyr Leu Gln Ser Gly Ser Leu Gly 
        275                 280                 285             


Gly Glu Tyr Arg Val Leu Phe Tyr Val Asp Ser Glu Lys Leu Lys Gln 
    290                 295                 300                 


Asn Asp Phe Asn Ser Val Glu Glu Lys Lys Cys Lys Ser Ser Gly Trp 
305                 310                 315                 320 


His Phe Val Val Lys Phe Ser Ser His Gly Cys Lys Glu Leu Glu Asn 
                325                 330                 335     


Ala Leu Lys Ala Ala Ser Gly Thr Gln Asn Asn Val Leu Arg Gly Glu 
            340                 345                 350         


Pro Phe Ile Arg Gly Gly Gly Ala Gly Phe Ile Ser Gly Leu Ser Tyr 
        355                 360                 365             


Leu Glu Leu Asp Asn Pro Ala Gly Asn Lys Arg Arg Tyr Ser Ala Trp 
    370                 375                 380                 


Ala Glu Ser Val Thr Asn Leu Pro Gln Val Ile Lys Gln Lys Leu Thr 
385                 390                 395                 400 


Pro Leu Tyr Glu Leu Val Lys Glu Val Pro Cys Ala Ser Val Lys Lys 
                405                 410                 415     


Leu Tyr Leu Lys Trp Ala Leu Glu Glu Tyr Leu Asp Glu Phe Asp Pro 
            420                 425                 430         


Cys His Cys Arg Pro Cys Gln Asn Gly Gly Leu Ala Thr Val Glu Gly 
        435                 440                 445             


Thr His Cys Leu Cys His Cys Lys Pro Tyr Thr Phe Gly Ala Ala Cys 
    450                 455                 460                 


Glu Gln Gly Val Leu Val Gly Asn Gln Ala Gly Gly Val Asp Gly Gly 
465                 470                 475                 480 


Trp Ser Cys Trp Ser Ser Trp Ser Pro Cys Val Gln Gly Lys Lys Thr 
                485                 490                 495     


Arg Ser Arg Glu Cys Asn Asn Pro Pro Pro Ser Gly Gly Gly Arg Ser 
            500                 505                 510         


Cys Val Gly Glu Thr Thr Glu Ser Thr Gln Cys Glu Asp Glu Glu Leu 
        515                 520                 525             


Glu His Leu Arg Leu Leu Glu Pro His Cys Phe Pro Leu Ser Leu Val 
    530                 535                 540                 


Pro Thr Glu Phe Cys Pro Ser Pro Pro Ala Leu Lys Asp Gly Phe Val 
545                 550                 555                 560 


Gln Asp Glu Gly Thr Met Phe Pro Val Gly Lys Asn Val Val Tyr Thr 
                565                 570                 575     


Cys Asn Glu Gly Tyr Ser Leu Ile Gly Asn Pro Val Ala Arg Cys Gly 
            580                 585                 590         


Glu Asp Leu Arg Trp Leu Val Gly Glu Met His Cys Gln Lys Ile Ala 
        595                 600                 605             


Cys Val Leu Pro Val Leu Met Asp Gly Ile Gln Ser His Pro Gln Lys 
    610                 615                 620                 


Pro Phe Tyr Thr Val Gly Glu Lys Val Thr Val Ser Cys Ser Gly Gly 
625                 630                 635                 640 


Met Ser Leu Glu Gly Pro Ser Ala Phe Leu Cys Gly Ser Ser Leu Lys 
                645                 650                 655     


Trp Ser Pro Glu Met Lys Asn Ala Arg Cys Val Gln Lys Glu Asn Pro 
            660                 665                 670         


Leu Thr Gln Ala Val Pro Lys Cys Gln Arg Trp Glu Lys Leu Gln Asn 
        675                 680                 685             


Ser Arg Cys Val Cys Lys Met Pro Tyr Glu Cys Gly Pro Ser Leu Asp 
    690                 695                 700                 


Val Cys Ala Gln Asp Glu Arg Ser Lys Arg Ile Leu Pro Leu Thr Val 
705                 710                 715                 720 


Cys Lys Met His Val Leu His Cys Gln Gly Arg Asn Tyr Thr Leu Thr 
                725                 730                 735     


Gly Arg Asp Ser Cys Thr Leu Pro Ala Ser Ala Glu Lys Ala Cys Gly 
            740                 745                 750         


Ala Cys Pro Leu Trp Gly Lys Cys Asp Ala Glu Ser Ser Lys Cys Val 
        755                 760                 765             


Cys Arg Glu Ala Ser Glu Cys Glu Glu Glu Gly Phe Ser Ile Cys Val 
    770                 775                 780                 


Glu Val Asn Gly Lys Glu Gln Thr Met Ser Glu Cys Glu Ala Gly Ala 
785                 790                 795                 800 


Leu Arg Cys Arg Gly Gln Ser Ile Ser Val Thr Ser Ile Arg Pro Cys 
                805                 810                 815     


Ala Ala Glu Thr Gln 
            820     


<210>  113
<211>  554
<212>  PRT
<213>  Homo Sapiens

<400>  113

Ala Ala Thr Pro Ala Ala Val Thr Cys Gln Leu Ser Asn Trp Ser Glu 
1               5                   10                  15      


Trp Thr Asp Cys Phe Pro Cys Gln Asp Lys Lys Tyr Arg His Arg Ser 
            20                  25                  30          


Leu Leu Gln Pro Asn Lys Phe Gly Gly Thr Ile Cys Ser Gly Asp Ile 
        35                  40                  45              


Trp Asp Gln Ala Ser Cys Ser Ser Ser Thr Thr Cys Val Arg Lys Ala 
    50                  55                  60                  


Gln Cys Gly Gln Asp Phe Gln Cys Lys Glu Thr Gly Arg Cys Leu Lys 
65                  70                  75                  80  


Arg His Leu Val Cys Asn Gly Asp Gln Asp Cys Leu Asp Gly Ser Asp 
                85                  90                  95      


Glu Asp Asp Cys Glu Asp Val Arg Ala Ile Asp Glu Asp Cys Ser Gln 
            100                 105                 110         


Tyr Glu Pro Ile Pro Gly Ser Gln Lys Ala Ala Leu Gly Tyr Asn Ile 
        115                 120                 125             


Leu Thr Gln Glu Asp Ala Gln Ser Val Tyr Asp Ala Ser Tyr Tyr Gly 
    130                 135                 140                 


Gly Gln Cys Glu Thr Val Tyr Asn Gly Glu Trp Arg Glu Leu Arg Tyr 
145                 150                 155                 160 


Asp Ser Thr Cys Glu Arg Leu Tyr Tyr Gly Asp Asp Glu Lys Tyr Phe 
                165                 170                 175     


Arg Lys Pro Tyr Asn Phe Leu Lys Tyr His Phe Glu Ala Leu Ala Asp 
            180                 185                 190         


Thr Gly Ile Ser Ser Glu Phe Tyr Asp Asn Ala Asn Asp Leu Leu Ser 
        195                 200                 205             


Lys Val Lys Lys Asp Lys Ser Asp Ser Phe Gly Val Thr Ile Gly Ile 
    210                 215                 220                 


Gly Pro Ala Gly Ser Pro Leu Leu Val Gly Val Gly Val Ser His Ser 
225                 230                 235                 240 


Gln Asp Thr Ser Phe Leu Asn Glu Leu Asn Lys Tyr Asn Glu Lys Lys 
                245                 250                 255     


Phe Ile Phe Thr Arg Ile Phe Thr Lys Val Gln Thr Ala His Phe Lys 
            260                 265                 270         


Met Arg Lys Asp Asp Ile Met Leu Asp Glu Gly Met Leu Gln Ser Leu 
        275                 280                 285             


Met Glu Leu Pro Asp Gln Tyr Asn Tyr Gly Met Tyr Ala Lys Phe Ile 
    290                 295                 300                 


Asn Asp Tyr Gly Thr His Tyr Ile Thr Ser Gly Ser Met Gly Gly Ile 
305                 310                 315                 320 


Tyr Glu Tyr Ile Leu Val Ile Asp Lys Ala Lys Met Glu Ser Leu Gly 
                325                 330                 335     


Ile Thr Ser Arg Asp Ile Thr Thr Cys Phe Gly Gly Ser Leu Gly Ile 
            340                 345                 350         


Gln Tyr Glu Asp Lys Ile Asn Val Gly Gly Gly Leu Ser Gly Asp His 
        355                 360                 365             


Cys Lys Lys Phe Gly Gly Gly Lys Thr Glu Arg Ala Arg Lys Ala Met 
    370                 375                 380                 


Ala Val Glu Asp Ile Ile Ser Arg Val Arg Gly Gly Ser Ser Gly Trp 
385                 390                 395                 400 


Ser Gly Gly Leu Ala Gln Asn Arg Ser Thr Ile Thr Tyr Arg Ser Trp 
                405                 410                 415     


Gly Arg Ser Leu Lys Tyr Asn Pro Val Val Ile Asp Phe Glu Met Gln 
            420                 425                 430         


Pro Ile His Glu Val Leu Arg His Thr Ser Leu Gly Pro Leu Glu Ala 
        435                 440                 445             


Lys Arg Gln Asn Leu Arg Arg Ala Leu Asp Gln Tyr Leu Met Glu Phe 
    450                 455                 460                 


Asn Ala Cys Arg Cys Gly Pro Cys Phe Asn Asn Gly Val Pro Ile Leu 
465                 470                 475                 480 


Glu Gly Thr Ser Cys Arg Cys Gln Cys Arg Leu Gly Ser Leu Gly Ala 
                485                 490                 495     


Ala Cys Glu Gln Thr Gln Thr Glu Gly Ala Lys Ala Asp Gly Ser Trp 
            500                 505                 510         


Ser Cys Trp Ser Ser Trp Ser Val Cys Arg Ala Gly Ile Gln Glu Arg 
        515                 520                 525             


Arg Arg Glu Cys Asp Asn Pro Ala Pro Gln Asn Gly Gly Ala Ser Cys 
    530                 535                 540                 


Pro Gly Arg Lys Val Gln Thr Gln Ala Cys 
545                 550                 


<210>  114
<211>  537
<212>  PRT
<213>  Homo Sapiens

<400>  114

Ser Val Asp Val Thr Leu Met Pro Ile Asp Cys Glu Leu Ser Ser Trp 
1               5                   10                  15      


Ser Ser Trp Thr Thr Cys Asp Pro Cys Gln Lys Lys Arg Tyr Arg Tyr 
            20                  25                  30          


Ala Tyr Leu Leu Gln Pro Ser Gln Phe His Gly Glu Pro Cys Asn Phe 
        35                  40                  45              


Ser Asp Lys Glu Val Glu Asp Cys Val Thr Asn Arg Pro Cys Arg Ser 
    50                  55                  60                  


Gln Val Arg Cys Glu Gly Phe Val Cys Ala Gln Thr Gly Arg Cys Val 
65                  70                  75                  80  


Asn Arg Arg Leu Leu Cys Asn Gly Asp Asn Asp Cys Gly Asp Gln Ser 
                85                  90                  95      


Asp Glu Ala Asn Cys Arg Arg Ile Tyr Lys Lys Cys Gln His Glu Met 
            100                 105                 110         


Asp Gln Tyr Trp Gly Ile Gly Ser Leu Ala Ser Gly Ile Asn Leu Phe 
        115                 120                 125             


Thr Asn Ser Phe Glu Gly Pro Val Leu Asp His Arg Tyr Tyr Ala Gly 
    130                 135                 140                 


Gly Cys Ser Pro His Tyr Ile Leu Asn Thr Arg Phe Arg Lys Pro Tyr 
145                 150                 155                 160 


Asn Val Glu Ser Tyr Thr Pro Gln Thr Gln Gly Lys Tyr Glu Phe Ile 
                165                 170                 175     


Leu Lys Glu Tyr Glu Ser Tyr Ser Asp Phe Glu Arg Asn Val Thr Glu 
            180                 185                 190         


Lys Met Ala Ser Lys Ser Gly Phe Ser Phe Gly Phe Lys Ile Pro Gly 
        195                 200                 205             


Ile Phe Glu Leu Gly Ile Ser Ser Gln Ser Asp Arg Gly Lys His Tyr 
    210                 215                 220                 


Ile Arg Arg Thr Lys Arg Phe Ser His Thr Lys Ser Val Phe Leu His 
225                 230                 235                 240 


Ala Arg Ser Asp Leu Glu Val Ala His Tyr Lys Leu Lys Pro Arg Ser 
                245                 250                 255     


Leu Met Leu His Tyr Glu Phe Leu Gln Arg Val Lys Arg Leu Pro Leu 
            260                 265                 270         


Glu Tyr Ser Tyr Gly Glu Tyr Arg Asp Leu Phe Arg Asp Phe Gly Thr 
        275                 280                 285             


His Tyr Ile Thr Glu Ala Val Leu Gly Gly Ile Tyr Glu Tyr Thr Leu 
    290                 295                 300                 


Val Met Asn Lys Glu Ala Met Glu Arg Gly Asp Tyr Thr Leu Asn Asn 
305                 310                 315                 320 


Val His Ala Cys Ala Lys Asn Asp Phe Lys Ile Gly Gly Ala Ile Glu 
                325                 330                 335     


Glu Val Tyr Val Ser Leu Gly Val Ser Val Gly Lys Cys Arg Gly Ile 
            340                 345                 350         


Leu Asn Glu Ile Lys Asp Arg Asn Lys Arg Asp Thr Met Val Glu Asp 
        355                 360                 365             


Leu Val Val Leu Val Arg Gly Gly Ala Ser Glu His Ile Thr Thr Leu 
    370                 375                 380                 


Ala Tyr Gln Glu Leu Pro Thr Ala Asp Leu Met Gln Glu Trp Gly Asp 
385                 390                 395                 400 


Ala Val Gln Tyr Asn Pro Ala Ile Ile Lys Val Lys Val Glu Pro Leu 
                405                 410                 415     


Tyr Glu Leu Val Thr Ala Thr Asp Phe Ala Tyr Ser Ser Thr Val Arg 
            420                 425                 430         


Gln Asn Met Lys Gln Ala Leu Glu Glu Phe Gln Lys Glu Val Ser Ser 
        435                 440                 445             


Cys His Cys Ala Pro Cys Gln Gly Asn Gly Val Pro Val Leu Lys Gly 
    450                 455                 460                 


Ser Arg Cys Asp Cys Ile Cys Pro Val Gly Ser Gln Gly Leu Ala Cys 
465                 470                 475                 480 


Glu Val Ser Tyr Arg Lys Asn Thr Pro Ile Asp Gly Lys Trp Asn Cys 
                485                 490                 495     


Trp Ser Asn Trp Ser Ser Cys Ser Gly Arg Arg Lys Thr Arg Gln Arg 
            500                 505                 510         


Gln Cys Asn Asn Pro Pro Pro Gln Asn Gly Gly Ser Pro Cys Ser Gly 
        515                 520                 525             


Pro Ala Ser Glu Thr Leu Asp Cys Ser 
    530                 535         


<210>  115
<211>  244
<212>  PRT
<213>  Homo Sapiens

<400>  115

Gln Tyr Thr Thr Ser Tyr Asp Pro Glu Leu Thr Glu Ser Ser Gly Ser 
1               5                   10                  15      


Ala Ser His Ile Asp Cys Arg Met Ser Pro Trp Ser Glu Trp Ser Gln 
            20                  25                  30          


Cys Asp Pro Cys Leu Arg Gln Met Phe Arg Ser Arg Ser Ile Glu Val 
        35                  40                  45              


Phe Gly Gln Phe Asn Gly Lys Arg Cys Thr Asp Ala Val Gly Asp Arg 
    50                  55                  60                  


Arg Gln Cys Val Pro Thr Glu Pro Cys Glu Asp Ala Glu Asp Asp Cys 
65                  70                  75                  80  


Gly Asn Asp Phe Gln Cys Ser Thr Gly Arg Cys Ile Lys Met Arg Leu 
                85                  90                  95      


Arg Cys Asn Gly Asp Asn Asp Cys Gly Asp Phe Ser Asp Glu Asp Asp 
            100                 105                 110         


Cys Glu Ser Glu Pro Arg Pro Pro Cys Arg Asp Arg Val Val Glu Glu 
        115                 120                 125             


Ser Glu Leu Ala Arg Thr Ala Gly Tyr Gly Ile Asn Ile Leu Gly Met 
    130                 135                 140                 


Asp Pro Leu Ser Thr Pro Phe Asp Asn Glu Phe Tyr Asn Gly Leu Cys 
145                 150                 155                 160 


Asn Arg Asp Arg Asp Gly Asn Thr Leu Thr Tyr Tyr Arg Arg Pro Trp 
                165                 170                 175     


Asn Val Ala Ser Leu Ile Tyr Glu Thr Lys Gly Glu Lys Asn Phe Arg 
            180                 185                 190         


Thr Glu His Tyr Glu Glu Gln Ile Glu Ala Phe Lys Ser Ile Ile Gln 
        195                 200                 205             


Glu Lys Thr Ser Asn Phe Asn Ala Ala Ile Ser Leu Lys Phe Thr Pro 
    210                 215                 220                 


Thr Glu Thr Asn Lys Ala Glu Gln Cys Cys Glu Glu Thr Ala Ser Ser 
225                 230                 235                 240 


Ile Ser Leu His 
                


<210>  116
<211>  302
<212>  PRT
<213>  Homo Sapiens

<400>  116

Gln Asn Leu Phe Thr Lys Asp Val Thr Val Ile Glu Gly Glu Val Ala 
1               5                   10                  15      


Thr Ile Ser Cys Gln Val Asn Lys Ser Asp Asp Ser Val Ile Gln Leu 
            20                  25                  30          


Leu Asn Pro Asn Arg Gln Thr Ile Tyr Phe Arg Asp Phe Arg Pro Leu 
        35                  40                  45              


Lys Asp Ser Arg Phe Gln Leu Leu Asn Phe Ser Ser Ser Glu Leu Lys 
    50                  55                  60                  


Val Ser Leu Thr Asn Val Ser Ile Ser Asp Glu Gly Arg Tyr Phe Cys 
65                  70                  75                  80  


Gln Leu Tyr Thr Asp Pro Pro Gln Glu Ser Tyr Thr Thr Ile Thr Val 
                85                  90                  95      


Leu Val Pro Pro Arg Asn Leu Met Ile Asp Ile Gln Lys Asp Thr Ala 
            100                 105                 110         


Val Glu Gly Glu Glu Ile Glu Val Asn Cys Thr Ala Met Ala Ser Lys 
        115                 120                 125             


Pro Ala Thr Thr Ile Arg Trp Phe Lys Gly Asn Thr Glu Leu Lys Gly 
    130                 135                 140                 


Lys Ser Glu Val Glu Glu Trp Ser Asp Met Tyr Thr Val Thr Ser Gln 
145                 150                 155                 160 


Leu Met Leu Lys Val His Lys Glu Asp Asp Gly Val Pro Val Ile Cys 
                165                 170                 175     


Gln Val Glu His Pro Ala Val Thr Gly Asn Leu Gln Thr Gln Arg Tyr 
            180                 185                 190         


Leu Glu Val Gln Tyr Lys Pro Gln Val His Ile Gln Met Thr Tyr Pro 
        195                 200                 205             


Leu Gln Gly Leu Thr Arg Glu Gly Asp Ala Leu Glu Leu Thr Cys Glu 
    210                 215                 220                 


Ala Ile Gly Lys Pro Gln Pro Val Met Val Thr Trp Val Arg Val Asp 
225                 230                 235                 240 


Asp Glu Met Pro Gln His Ala Val Leu Ser Gly Pro Asn Leu Phe Ile 
                245                 250                 255     


Asn Asn Leu Asn Lys Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Ser 
            260                 265                 270         


Asn Ile Val Gly Lys Ala His Ser Asp Tyr Met Leu Tyr Val Tyr Asp 
        275                 280                 285             


Ser Arg Ala Gly Glu Glu Gly Ser Ile Arg Ala Val Asp His 
    290                 295                 300         


<210>  117
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  117

Met Pro Val Lys Thr Ser Lys Ala Tyr Leu Thr Val Leu Gly Val Pro 
1               5                   10                  15      


Glu Lys Pro Gln Ile Ser Gly Phe Ser Ser Pro Val Met Glu Gly Asp 
            20                  25                  30          


Leu Met Gln Leu Thr Cys Lys Thr Ser Gly Ser Lys Pro Ala Ala Asp 
        35                  40                  45              


Ile Arg Trp Phe Lys Asn Asp Lys Glu Ile Lys Asp Val Lys Tyr Leu 
    50                  55                  60                  


Lys Glu Glu Asp Ala Asn Arg Lys Thr Phe Thr Val Ser Ser Thr Leu 
65                  70                  75                  80  


Asp Phe Arg Val Asp Arg Ser Asp Asp Gly Val Ala Val Ile Cys Arg 
                85                  90                  95      


Val Asp His Glu Ser Leu Asn Ala Thr Pro Gln Val Ala Met Gln Val 
            100                 105                 110         


Leu Glu Ile His Tyr Thr Pro Ser Val Lys Ile Ile Pro Ser Thr Pro 
        115                 120                 125             


Phe Pro Gln Glu Gly Gln Pro Leu Ile Leu Thr Cys Glu Ser Lys Gly 
    130                 135                 140                 


Lys Pro Leu Pro Glu Pro Val Leu Trp Thr Lys Asp Gly Gly Glu Leu 
145                 150                 155                 160 


Pro Asp Pro Asp Arg Met Val Val Ser Gly Arg Glu Leu Asn Ile Leu 
                165                 170                 175     


Phe Leu Asn Lys Thr Asp Asn Gly Thr Tyr Arg Cys Glu Ala Thr Asn 
            180                 185                 190         


Thr Ile Gly Gln Ser Ser Ala Glu Tyr Val Leu Ile Val His Asp Pro 
        195                 200                 205             


Asn Ala Leu Ala Gly Gln Asn Gly Pro Asp His 
    210                 215                 


<210>  118
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  118

Met Val Lys Ala Gly Thr Cys Cys Ala Thr Cys Lys Glu Phe Tyr Gln 
1               5                   10                  15      


Met Lys Gln Thr Val Leu Gln Leu Lys Gln Lys Ile Ala Leu Leu Pro 
            20                  25                  30          


Asn Asn Ala Ala Asp Leu Gly Lys Tyr Ile Thr Gly Asp Lys Val Leu 
        35                  40                  45              


Ala Ser Asn Thr Tyr Leu Pro Gly Pro Pro Gly Leu Pro Gly Gly Gln 
    50                  55                  60                  


Gly Pro Pro Gly Ser Pro Gly Pro Lys Gly Ser Pro Gly Phe Pro Gly 
65                  70                  75                  80  


Met Pro Gly Pro Pro Gly Gln Pro Gly Pro Arg Gly Ser Met Gly Pro 
                85                  90                  95      


Met Gly Pro Ser Pro Asp Leu Ser His Ile Lys Gln Gly Arg Arg Gly 
            100                 105                 110         


Pro Val Gly Pro Pro Gly Ala Pro Gly Arg Asp Gly Ser Lys Gly Glu 
        115                 120                 125             


Arg Gly Ala Pro Gly Pro Arg Gly Ser Pro Gly Pro Pro Gly Ser Phe 
    130                 135                 140                 


Asp Phe Leu Leu Leu Met Leu Ala Asp Ile Arg Asn Asp Ile Thr Glu 
145                 150                 155                 160 


Leu Gln Glu Lys Val Phe Gly His Arg Thr His Ser Ser Ala Glu Glu 
                165                 170                 175     


Phe Pro Leu Pro Gln Glu Phe Pro Ser Tyr Pro Glu Ala Met Asp Leu 
            180                 185                 190         


Gly Ser Gly Asp Asp His Pro Arg Arg Thr Glu Thr Arg Asp Leu Arg 
        195                 200                 205             


Ala Pro Arg Asp Phe Tyr Pro 
    210                 215 


<210>  119
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  119

Lys Ser Met Gln Val Pro Phe Ser Arg Cys Cys Phe Ser Phe Ala Glu 
1               5                   10                  15      


Gln Glu Ile Pro Leu Arg Ala Ile Leu Cys Tyr Arg Asn Thr Ser Ser 
            20                  25                  30          


Ile Cys Ser Asn Glu Gly Leu Ile Phe Lys Leu Lys Arg Gly Lys Glu 
        35                  40                  45              


Ala Cys Ala Leu Asp Thr Val Gly Trp Val Gln Arg His Arg Lys Met 
    50                  55                  60                  


Leu Arg His Cys Pro Ser Lys Arg Lys 
65                  70              


<210>  120
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  120

Gly Pro Ala Ser Val Pro Thr Thr Cys Cys Phe Asn Leu Ala Asn Arg 
1               5                   10                  15      


Lys Ile Pro Leu Gln Arg Leu Glu Ser Tyr Arg Arg Ile Thr Ser Gly 
            20                  25                  30          


Lys Cys Pro Gln Lys Ala Val Ile Phe Lys Thr Lys Leu Ala Lys Asp 
        35                  40                  45              


Ile Cys Ala Asp Pro Lys Lys Lys Trp Val Gln Asp Ser Met Lys Tyr 
    50                  55                  60                  


Leu Asp Gln Lys Ser Pro Thr Pro Lys Pro 
65                  70                  


<210>  121
<211>  82
<212>  PRT
<213>  Homo Sapiens

<400>  121

Phe Asn Pro Gln Gly Leu Ala Gln Pro Asp Ala Leu Asn Val Pro Ser 
1               5                   10                  15      


Thr Cys Cys Phe Thr Phe Ser Ser Lys Lys Ile Ser Leu Gln Arg Leu 
            20                  25                  30          


Lys Ser Tyr Val Ile Thr Thr Ser Arg Cys Pro Gln Lys Ala Val Ile 
        35                  40                  45              


Phe Arg Thr Lys Leu Gly Lys Glu Ile Cys Ala Asp Pro Lys Glu Lys 
    50                  55                  60                  


Trp Val Gln Asn Tyr Met Lys His Leu Gly Arg Lys Ala His Thr Leu 
65                  70                  75                  80  


Lys Thr 
        


<210>  122
<211>  66
<212>  PRT
<213>  Homo Sapiens

<400>  122

Gly Pro Tyr His Pro Ser Glu Cys Cys Phe Thr Tyr Thr Thr Tyr Lys 
1               5                   10                  15      


Ile Pro Arg Gln Arg Ile Met Asp Tyr Tyr Glu Thr Asn Ser Gln Cys 
            20                  25                  30          


Ser Lys Pro Gly Ile Val Phe Ile Thr Lys Arg Gly His Ser Val Cys 
        35                  40                  45              


Thr Asn Pro Ser Asp Lys Trp Val Gln Asp Tyr Ile Lys Asp Met Lys 
    50                  55                  60                  


Glu Asn 
65      


<210>  123
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  123

Gln Phe Thr Asn Asp Ala Glu Thr Glu Leu Met Met Ser Lys Leu Pro 
1               5                   10                  15      


Leu Glu Asn Pro Val Val Leu Asn Ser Phe His Phe Ala Ala Asp Cys 
            20                  25                  30          


Cys Thr Ser Tyr Ile Ser Gln Ser Ile Pro Cys Ser Leu Met Lys Ser 
        35                  40                  45              


Tyr Phe Glu Thr Ser Ser Glu Cys Ser Lys Pro Gly Val Ile Phe Leu 
    50                  55                  60                  


Thr Lys Lys Gly Arg Gln Val Cys Ala Lys Pro Ser Gly Pro Gly Val 
65                  70                  75                  80  


Gln Asp Cys Met Lys Lys Leu Lys Pro Tyr Ser Ile 
                85                  90          


<210>  124
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  124

Gln Pro Lys Val Pro Glu Trp Val Asn Thr Pro Ser Thr Cys Cys Leu 
1               5                   10                  15      


Lys Tyr Tyr Glu Lys Val Leu Pro Arg Arg Leu Val Val Gly Tyr Arg 
            20                  25                  30          


Lys Ala Leu Asn Cys His Leu Pro Ala Ile Ile Phe Val Thr Lys Arg 
        35                  40                  45              


Asn Arg Glu Val Cys Thr Asn Pro Asn Asp Asp Trp Val Gln Glu Tyr 
    50                  55                  60                  


Ile Lys Asp Pro Asn Leu Pro Leu Leu Pro Thr Arg Asn Leu Ser Thr 
65                  70                  75                  80  


Val Lys Ile Ile Thr Ala Lys Asn Gly Gln Pro Gln Leu Leu Asn Ser 
                85                  90                  95      


Gln 
    


<210>  125
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  125

Ala Arg Gly Thr Asn Val Gly Arg Glu Cys Cys Leu Glu Tyr Phe Lys 
1               5                   10                  15      


Gly Ala Ile Pro Leu Arg Lys Leu Lys Thr Trp Tyr Gln Thr Ser Glu 
            20                  25                  30          


Asp Cys Ser Arg Asp Ala Ile Val Phe Val Thr Val Gln Gly Arg Ala 
        35                  40                  45              


Ile Cys Ser Asp Pro Asn Asn Lys Arg Val Lys Asn Ala Val Lys Tyr 
    50                  55                  60                  


Leu Gln Ser Leu Glu Arg Ser 
65                  70      


<210>  126
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  126

Ala Gln Val Gly Thr Asn Lys Glu Leu Cys Cys Leu Val Tyr Thr Ser 
1               5                   10                  15      


Trp Gln Ile Pro Gln Lys Phe Ile Val Asp Tyr Ser Glu Thr Ser Pro 
            20                  25                  30          


Gln Cys Pro Lys Pro Gly Val Ile Leu Leu Thr Lys Arg Gly Arg Gln 
        35                  40                  45              


Ile Cys Ala Asp Pro Asn Lys Lys Trp Val Gln Lys Tyr Ile Ser Asp 
    50                  55                  60                  


Leu Lys Leu Asn Ala 
65                  


<210>  127
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  127

Gly Thr Asn Asp Ala Glu Asp Cys Cys Leu Ser Val Thr Gln Lys Pro 
1               5                   10                  15      


Ile Pro Gly Tyr Ile Val Arg Asn Phe His Tyr Leu Leu Ile Lys Asp 
            20                  25                  30          


Gly Cys Arg Val Pro Ala Val Val Phe Thr Thr Leu Arg Gly Arg Gln 
        35                  40                  45              


Leu Cys Ala Pro Pro Asp Gln Pro Trp Val Glu Arg Ile Ile Gln Arg 
    50                  55                  60                  


Leu Gln Arg Thr Ser Ala Lys Met Lys Arg Arg Ser Ser 
65                  70                  75          


<210>  128
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  128

Gln Pro Asp Ala Ile Asn Ala Pro Val Thr Cys Cys Tyr Asn Phe Thr 
1               5                   10                  15      


Asn Arg Lys Ile Ser Val Gln Arg Leu Ala Ser Tyr Arg Arg Ile Thr 
            20                  25                  30          


Ser Ser Lys Cys Pro Lys Glu Ala Val Ile Phe Lys Thr Ile Val Ala 
        35                  40                  45              


Lys Glu Ile Cys Ala Asp Pro Lys Gln Lys Trp Val Gln Asp Ser Met 
    50                  55                  60                  


Asp His Leu Asp Lys Gln Thr Gln Thr Pro Lys Thr 
65                  70                  75      


<210>  129
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  129

Ala Ser Asn Phe Asp Cys Cys Leu Gly Tyr Thr Asp Arg Ile Leu His 
1               5                   10                  15      


Pro Lys Phe Ile Val Gly Phe Thr Arg Gln Leu Ala Asn Glu Gly Cys 
            20                  25                  30          


Asp Ile Asn Ala Ile Ile Phe His Thr Lys Lys Lys Leu Ser Val Cys 
        35                  40                  45              


Ala Asn Pro Lys Gln Thr Trp Val Lys Tyr Ile Val Arg Leu Leu Ser 
    50                  55                  60                  


Lys Lys Val Lys Asn Met 
65                  70  


<210>  130
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  130

Ser Asp Gly Gly Ala Gln Asp Cys Cys Leu Lys Tyr Ser Gln Arg Lys 
1               5                   10                  15      


Ile Pro Ala Lys Val Val Arg Ser Tyr Arg Lys Gln Glu Pro Ser Leu 
            20                  25                  30          


Gly Cys Ser Ile Pro Ala Ile Leu Phe Leu Pro Arg Lys Arg Ser Gln 
        35                  40                  45              


Ala Glu Leu Cys Ala Asp Pro Lys Glu Leu Trp Val Gln Gln Leu Met 
    50                  55                  60                  


Gln His Leu Asp Lys Thr Pro Ser Pro Gln Lys Pro Ala Gln Gly Cys 
65                  70                  75                  80  


Arg Lys Asp Arg Gly Ala Ser Lys Thr Gly Lys Lys Gly Lys Gly Ser 
                85                  90                  95      


Lys Gly Cys Lys Arg Thr Glu Arg Ser Gln Thr Pro Lys Gly Pro 
            100                 105                 110     


<210>  131
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  131

Gly Pro Tyr Gly Ala Asn Met Glu Asp Ser Val Cys Cys Arg Asp Tyr 
1               5                   10                  15      


Val Arg Tyr Arg Leu Pro Leu Arg Val Val Lys His Phe Tyr Trp Thr 
            20                  25                  30          


Ser Asp Ser Cys Pro Arg Pro Gly Val Val Leu Leu Thr Phe Arg Asp 
        35                  40                  45              


Lys Glu Ile Cys Ala Asp Pro Arg Val Pro Trp Val Lys Met Ile Leu 
    50                  55                  60                  


Asn Lys Leu Ser Gln 
65                  


<210>  132
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  132

Asn Pro Val Leu Leu Asp Arg Phe His Ala Thr Ser Ala Asp Cys Cys 
1               5                   10                  15      


Ile Ser Tyr Thr Pro Arg Ser Ile Pro Cys Ser Leu Leu Glu Ser Tyr 
            20                  25                  30          


Phe Glu Thr Asn Ser Glu Cys Ser Lys Pro Gly Val Ile Phe Leu Thr 
        35                  40                  45              


Lys Lys Gly Arg Arg Phe Cys Ala Asn Pro Ser Asp Lys Gln Val Gln 
    50                  55                  60                  


Val Cys Met Arg Met Leu Lys Leu Asp Thr Arg Ile Lys Thr Arg Lys 
65                  70                  75                  80  


Asn 
    


<210>  133
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  133

Val Val Ile Pro Ser Pro Cys Cys Met Phe Phe Val Ser Lys Arg Ile 
1               5                   10                  15      


Pro Glu Asn Arg Val Val Ser Tyr Gln Leu Ser Ser Arg Ser Ile Cys 
            20                  25                  30          


Leu Lys Ala Gly Val Ile Phe Thr Thr Lys Lys Gly Gln Gln Phe Cys 
        35                  40                  45              


Gly Asp Pro Lys Gln Glu Trp Val Gln Arg Tyr Met Lys Asn Leu Asp 
    50                  55                  60                  


Ala Lys Gln Lys Lys Ala Ser Pro Arg Ala Arg Ala Val Ala Val Lys 
65                  70                  75                  80  


Gly Pro Val Gln Arg Tyr Pro Gly Asn Gln Thr Thr Cys 
                85                  90              


<210>  134
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  134

Gln Gly Val Phe Glu Asp Cys Cys Leu Ala Tyr His Tyr Pro Ile Gly 
1               5                   10                  15      


Trp Ala Val Leu Arg Arg Ala Trp Thr Tyr Arg Ile Gln Glu Val Ser 
            20                  25                  30          


Gly Ser Cys Asn Leu Pro Ala Ala Ile Phe Tyr Leu Pro Lys Arg His 
        35                  40                  45              


Arg Lys Val Cys Gly Asn Pro Lys Ser Arg Glu Val Gln Arg Ala Met 
    50                  55                  60                  


Lys Leu Leu Asp Ala Arg Asn Lys Val Phe Ala Lys Leu His His Asn 
65                  70                  75                  80  


Thr Gln Thr Phe Gln Ala Gly Pro His Ala Val Lys Lys Leu Ser Ser 
                85                  90                  95      


Gly Asn Ser Lys Leu Ser Ser Ser Lys Phe Ser Asn Pro Ile Ser Ser 
            100                 105                 110         


Ser Lys Arg Asn Val Ser Leu Leu Ile Ser Ala Asn Ser Gly Leu 
        115                 120                 125         


<210>  135
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  135

Thr Arg Gly Ser Asp Ile Ser Lys Thr Cys Cys Phe Gln Tyr Ser His 
1               5                   10                  15      


Lys Pro Leu Pro Trp Thr Trp Val Arg Ser Tyr Glu Phe Thr Ser Asn 
            20                  25                  30          


Ser Cys Ser Gln Arg Ala Val Ile Phe Thr Thr Lys Arg Gly Lys Lys 
        35                  40                  45              


Val Cys Thr His Pro Arg Lys Lys Trp Val Gln Lys Tyr Ile Ser Leu 
    50                  55                  60                  


Leu Lys Thr Pro Lys Gln Leu 
65                  70      


<210>  136
<211>  88
<212>  PRT
<213>  Homo Sapiens

<400>  136

Phe Leu Leu Pro Pro Ser Thr Ala Cys Cys Thr Gln Leu Tyr Arg Lys 
1               5                   10                  15      


Pro Leu Ser Asp Lys Leu Leu Arg Lys Val Ile Gln Val Glu Leu Gln 
            20                  25                  30          


Glu Ala Asp Gly Asp Cys His Leu Gln Ala Phe Val Leu His Leu Ala 
        35                  40                  45              


Gln Arg Ser Ile Cys Ile His Pro Gln Asn Pro Ser Leu Ser Gln Trp 
    50                  55                  60                  


Phe Glu His Gln Glu Arg Lys Leu His Gly Thr Leu Pro Lys Leu Asn 
65                  70                  75                  80  


Phe Gly Met Leu Arg Lys Met Gly 
                85              


<210>  137
<211>  108
<212>  PRT
<213>  Homo Sapiens

<400>  137

Ser Glu Ala Ile Leu Pro Ile Ala Ser Ser Cys Cys Thr Glu Val Ser 
1               5                   10                  15      


His His Ile Ser Arg Arg Leu Leu Glu Arg Val Asn Met Cys Arg Ile 
            20                  25                  30          


Gln Arg Ala Asp Gly Asp Cys Asp Leu Ala Ala Val Ile Leu His Val 
        35                  40                  45              


Lys Arg Arg Arg Ile Cys Val Ser Pro His Asn His Thr Val Lys Gln 
    50                  55                  60                  


Trp Met Lys Val Gln Ala Ala Lys Lys Asn Gly Lys Gly Asn Val Cys 
65                  70                  75                  80  


His Arg Lys Lys His His Gly Lys Arg Asn Ser Asn Arg Ala His Gln 
                85                  90                  95      


Gly Lys His Glu Thr Tyr Gly His Lys Thr Pro Tyr 
            100                 105             


<210>  138
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  138

Ser Leu Ala Ala Asp Thr Pro Thr Ala Cys Cys Phe Ser Tyr Thr Ser 
1               5                   10                  15      


Arg Gln Ile Pro Gln Asn Phe Ile Ala Asp Tyr Phe Glu Thr Ser Ser 
            20                  25                  30          


Gln Cys Ser Lys Pro Gly Val Ile Phe Leu Thr Lys Arg Ser Arg Gln 
        35                  40                  45              


Val Cys Ala Asp Pro Ser Glu Glu Trp Val Gln Lys Tyr Val Ser Asp 
    50                  55                  60                  


Leu Glu Leu Ser Ala 
65                  


<210>  139
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  139

Leu Ala Ala Asp Thr Pro Thr Ala Cys Cys Phe Ser Tyr Thr Ser Arg 
1               5                   10                  15      


Gln Ile Pro Gln Asn Phe Ile Ala Asp Tyr Phe Glu Thr Ser Ser Gln 
            20                  25                  30          


Cys Ser Lys Pro Ser Val Ile Phe Leu Thr Lys Arg Gly Arg Gln Val 
        35                  40                  45              


Cys Ala Asp Pro Ser Glu Glu Trp Val Gln Lys Tyr Val Ser Asp Leu 
    50                  55                  60                  


Glu Pro Ser Ala 
65              


<210>  140
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  140

Ala Pro Met Gly Ser Asp Pro Pro Thr Ala Cys Cys Phe Ser Tyr Thr 
1               5                   10                  15      


Ala Arg Lys Leu Pro Arg Asn Phe Val Val Asp Tyr Tyr Glu Thr Ser 
            20                  25                  30          


Ser Leu Cys Ser Gln Pro Ala Val Val Phe Gln Thr Lys Arg Ser Lys 
        35                  40                  45              


Gln Val Cys Ala Asp Pro Ser Glu Ser Trp Val Gln Glu Tyr Val Tyr 
    50                  55                  60                  


Asp Leu Glu Leu Asn 
65                  


<210>  141
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  141

Ala Pro Met Gly Ser Asp Pro Pro Thr Ala Cys Cys Phe Ser Tyr Thr 
1               5                   10                  15      


Ala Arg Lys Leu Pro His Asn Phe Val Val Asp Tyr Tyr Glu Thr Ser 
            20                  25                  30          


Ser Leu Cys Ser Gln Pro Ala Val Val Phe Gln Thr Lys Arg Gly Lys 
        35                  40                  45              


Gln Val Cys Ala Asp Pro Ser Glu Ser Trp Val Gln Glu Tyr Val Tyr 
    50                  55                  60                  


Asp Leu Glu Leu Asn 
65                  


<210>  142
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  142

Ser Pro Tyr Ser Ser Asp Thr Thr Pro Cys Cys Phe Ala Tyr Ile Ala 
1               5                   10                  15      


Arg Pro Leu Pro Arg Ala His Ile Lys Glu Tyr Phe Tyr Thr Ser Gly 
            20                  25                  30          


Lys Cys Ser Asn Pro Ala Val Val Phe Val Thr Arg Lys Asn Arg Gln 
        35                  40                  45              


Val Cys Ala Asn Pro Glu Lys Lys Trp Val Arg Glu Tyr Ile Asn Ser 
    50                  55                  60                  


Leu Glu Met Ser 
65              


<210>  143
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  143

Gln Pro Val Gly Ile Asn Thr Ser Thr Thr Cys Cys Tyr Arg Phe Ile 
1               5                   10                  15      


Asn Lys Lys Ile Pro Lys Gln Arg Leu Glu Ser Tyr Arg Arg Thr Thr 
            20                  25                  30          


Ser Ser His Cys Pro Arg Glu Ala Val Ile Phe Lys Thr Lys Leu Asp 
        35                  40                  45              


Lys Glu Ile Cys Ala Asp Pro Thr Gln Lys Trp Val Gln Asp Phe Met 
    50                  55                  60                  


Lys His Leu Asp Lys Lys Thr Gln Thr Pro Lys Leu 
65                  70                  75      


<210>  144
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  144

Gln Pro Asp Ser Val Ser Ile Pro Ile Thr Cys Cys Phe Asn Val Ile 
1               5                   10                  15      


Asn Arg Lys Ile Pro Ile Gln Arg Leu Glu Ser Tyr Thr Arg Ile Thr 
            20                  25                  30          


Asn Ile Gln Cys Pro Lys Glu Ala Val Ile Phe Lys Thr Gln Arg Gly 
        35                  40                  45              


Lys Glu Val Cys Ala Asp Pro Lys Glu Arg Trp Val Arg Asp Ser Met 
    50                  55                  60                  


Lys His Leu Asp Gln Ile Phe Gln Asn Leu Lys Pro 
65                  70                  75      


<210>  145
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  145

Thr Thr Pro Glu Pro Cys Glu Leu Asp Asp Glu Asp Phe Arg Cys Val 
1               5                   10                  15      


Cys Asn Phe Ser Glu Pro Gln Pro Asp Trp Ser Glu Ala Phe Gln Cys 
            20                  25                  30          


Val Ser Ala Val Glu Val Glu Ile His Ala Gly Gly Leu Asn Leu Glu 
        35                  40                  45              


Pro Phe Leu Lys Arg Val Asp Ala Asp Ala Asp Pro Arg Gln Tyr Ala 
    50                  55                  60                  


Asp Thr Val Lys Ala Leu Arg Val Arg Arg Leu Thr Val Gly Ala Ala 
65                  70                  75                  80  


Gln Val Pro Ala Gln Leu Leu Val Gly Ala Leu Arg Val Leu Ala Tyr 
                85                  90                  95      


Ser Arg Leu Lys Glu Leu Thr Leu Glu Asp Leu Lys Ile Thr Gly Thr 
            100                 105                 110         


Met Pro Pro Leu Pro Leu Glu Ala Thr Gly Leu Ala Leu Ser Ser Leu 
        115                 120                 125             


Arg Leu Arg Asn Val Ser Trp Ala Thr Gly Arg Ser Trp Leu Ala Glu 
    130                 135                 140                 


Leu Gln Gln Trp Leu Lys Pro Gly Leu Lys Val Leu Ser Ile Ala Gln 
145                 150                 155                 160 


Ala His Ser Pro Ala Phe Ser Cys Glu Gln Val Arg Ala Phe Pro Ala 
                165                 170                 175     


Leu Thr Ser Leu Asp Leu Ser Asp Asn Pro Gly Leu Gly Glu Arg Gly 
            180                 185                 190         


Leu Met Ala Ala Leu Cys Pro His Lys Phe Pro Ala Ile Gln Asn Leu 
        195                 200                 205             


Ala Leu Arg Asn Thr Gly Met Glu Thr Pro Thr Gly Val Cys Ala Ala 
    210                 215                 220                 


Leu Ala Ala Ala Gly Val Gln Pro His Ser Leu Asp Leu Ser His Asn 
225                 230                 235                 240 


Ser Leu Arg Ala Thr Val Asn Pro Ser Ala Pro Arg Cys Met Trp Ser 
                245                 250                 255     


Ser Ala Leu Asn Ser Leu Asn Leu Ser Phe Ala Gly Leu Glu Gln Val 
            260                 265                 270         


Pro Lys Gly Leu Pro Ala Lys Leu Arg Val Leu Asp Leu Ser Cys Asn 
        275                 280                 285             


Arg Leu Asn Arg Ala Pro Gln Pro Asp Glu Leu Pro Glu Val Asp Asn 
    290                 295                 300                 


Leu Thr Leu Asp Gly Asn Pro Phe Leu Val Pro Gly Thr Ala Leu Pro 
305                 310                 315                 320 


His Glu Gly Ser Met Asn 
                325     


<210>  146
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  146

Ala Tyr Tyr Gln Gln Leu Asn Thr Glu Leu Lys Glu Asn Leu Lys Asp 
1               5                   10                  15      


Thr Met Thr Lys Arg Tyr His Gln Pro Gly His Glu Ala Val Thr Ser 
            20                  25                  30          


Ala Val Asp Gln Leu Gln Gln Glu Phe His Cys Cys Gly Ser Asn Asn 
        35                  40                  45              


Ser Gln Asp Trp Arg Asp Ser Glu Trp Ile Arg Ser Gln Glu Ala Gly 
    50                  55                  60                  


Gly Arg Val Val Pro Asp Ser Cys Cys Lys Thr Val Val Ala Leu Cys 
65                  70                  75                  80  


Gly Gln Arg Asp His Ala Ser Asn Ile Tyr Lys Val Glu Gly Gly Cys 
                85                  90                  95      


Ile Thr Lys Leu Glu Thr Phe Ile Gln Glu His Leu Arg 
            100                 105                 


<210>  147
<211>  1009
<212>  PRT
<213>  Homo Sapiens

<400>  147

Ser Ser Leu Gly Gly Thr Asp Lys Glu Leu Arg Leu Val Asp Gly Glu 
1               5                   10                  15      


Asn Lys Cys Ser Gly Arg Val Glu Val Lys Val Gln Glu Glu Trp Gly 
            20                  25                  30          


Thr Val Cys Asn Asn Gly Trp Ser Met Glu Ala Val Ser Val Ile Cys 
        35                  40                  45              


Asn Gln Leu Gly Cys Pro Thr Ala Ile Lys Ala Pro Gly Trp Ala Asn 
    50                  55                  60                  


Ser Ser Ala Gly Ser Gly Arg Ile Trp Met Asp His Val Ser Cys Arg 
65                  70                  75                  80  


Gly Asn Glu Ser Ala Leu Trp Asp Cys Lys His Asp Gly Trp Gly Lys 
                85                  90                  95      


His Ser Asn Cys Thr His Gln Gln Asp Ala Gly Val Thr Cys Ser Asp 
            100                 105                 110         


Gly Ser Asn Leu Glu Met Arg Leu Thr Arg Gly Gly Asn Met Cys Ser 
        115                 120                 125             


Gly Arg Ile Glu Ile Lys Phe Gln Gly Arg Trp Gly Thr Val Cys Asp 
    130                 135                 140                 


Asp Asn Phe Asn Ile Asp His Ala Ser Val Ile Cys Arg Gln Leu Glu 
145                 150                 155                 160 


Cys Gly Ser Ala Val Ser Phe Ser Gly Ser Ser Asn Phe Gly Glu Gly 
                165                 170                 175     


Ser Gly Pro Ile Trp Phe Asp Asp Leu Ile Cys Asn Gly Asn Glu Ser 
            180                 185                 190         


Ala Leu Trp Asn Cys Lys His Gln Gly Trp Gly Lys His Asn Cys Asp 
        195                 200                 205             


His Ala Glu Asp Ala Gly Val Ile Cys Ser Lys Gly Ala Asp Leu Ser 
    210                 215                 220                 


Leu Arg Leu Val Asp Gly Val Thr Glu Cys Ser Gly Arg Leu Glu Val 
225                 230                 235                 240 


Arg Phe Gln Gly Glu Trp Gly Thr Ile Cys Asp Asp Gly Trp Asp Ser 
                245                 250                 255     


Tyr Asp Ala Ala Val Ala Cys Lys Gln Leu Gly Cys Pro Thr Ala Val 
            260                 265                 270         


Thr Ala Ile Gly Arg Val Asn Ala Ser Lys Gly Phe Gly His Ile Trp 
        275                 280                 285             


Leu Asp Ser Val Ser Cys Gln Gly His Glu Pro Ala Val Trp Gln Cys 
    290                 295                 300                 


Lys His His Glu Trp Gly Lys His Tyr Cys Asn His Asn Glu Asp Ala 
305                 310                 315                 320 


Gly Val Thr Cys Ser Asp Gly Ser Asp Leu Glu Leu Arg Leu Arg Gly 
                325                 330                 335     


Gly Gly Ser Arg Cys Ala Gly Thr Val Glu Val Glu Ile Gln Arg Leu 
            340                 345                 350         


Leu Gly Lys Val Cys Asp Arg Gly Trp Gly Leu Lys Glu Ala Asp Val 
        355                 360                 365             


Val Cys Arg Gln Leu Gly Cys Gly Ser Ala Leu Lys Thr Ser Tyr Gln 
    370                 375                 380                 


Val Tyr Ser Lys Ile Gln Ala Thr Asn Thr Trp Leu Phe Leu Ser Ser 
385                 390                 395                 400 


Cys Asn Gly Asn Glu Thr Ser Leu Trp Asp Cys Lys Asn Trp Gln Trp 
                405                 410                 415     


Gly Gly Leu Thr Cys Asp His Tyr Glu Glu Ala Lys Ile Thr Cys Ser 
            420                 425                 430         


Ala His Arg Glu Pro Arg Leu Val Gly Gly Asp Ile Pro Cys Ser Gly 
        435                 440                 445             


Arg Val Glu Val Lys His Gly Asp Thr Trp Gly Ser Ile Cys Asp Ser 
    450                 455                 460                 


Asp Phe Ser Leu Glu Ala Ala Ser Val Leu Cys Arg Glu Leu Gln Cys 
465                 470                 475                 480 


Gly Thr Val Val Ser Ile Leu Gly Gly Ala His Phe Gly Glu Gly Asn 
                485                 490                 495     


Gly Gln Ile Trp Ala Glu Glu Phe Gln Cys Glu Gly His Glu Ser His 
            500                 505                 510         


Leu Ser Leu Cys Pro Val Ala Pro Arg Pro Glu Gly Thr Cys Ser His 
        515                 520                 525             


Ser Arg Asp Val Gly Val Val Cys Ser Arg Tyr Thr Glu Ile Arg Leu 
    530                 535                 540                 


Val Asn Gly Lys Thr Pro Cys Glu Gly Arg Val Glu Leu Lys Thr Leu 
545                 550                 555                 560 


Gly Ala Trp Gly Ser Leu Cys Asn Ser His Trp Asp Ile Glu Asp Ala 
                565                 570                 575     


His Val Leu Cys Gln Gln Leu Lys Cys Gly Val Ala Leu Ser Thr Pro 
            580                 585                 590         


Gly Gly Ala Arg Phe Gly Lys Gly Asn Gly Gln Ile Trp Arg His Met 
        595                 600                 605             


Phe His Cys Thr Gly Thr Glu Gln His Met Gly Asp Cys Pro Val Thr 
    610                 615                 620                 


Ala Leu Gly Ala Ser Leu Cys Pro Ser Glu Gln Val Ala Ser Val Ile 
625                 630                 635                 640 


Cys Ser Gly Asn Gln Ser Gln Thr Leu Ser Ser Cys Asn Ser Ser Ser 
                645                 650                 655     


Leu Gly Pro Thr Arg Pro Thr Ile Pro Glu Glu Ser Ala Val Ala Cys 
            660                 665                 670         


Ile Glu Ser Gly Gln Leu Arg Leu Val Asn Gly Gly Gly Arg Cys Ala 
        675                 680                 685             


Gly Arg Val Glu Ile Tyr His Glu Gly Ser Trp Gly Thr Ile Cys Asp 
    690                 695                 700                 


Asp Ser Trp Asp Leu Ser Asp Ala His Val Val Cys Arg Gln Leu Gly 
705                 710                 715                 720 


Cys Gly Glu Ala Ile Asn Ala Thr Gly Ser Ala His Phe Gly Glu Gly 
                725                 730                 735     


Thr Gly Pro Ile Trp Leu Asp Glu Met Lys Cys Asn Gly Lys Glu Ser 
            740                 745                 750         


Arg Ile Trp Gln Cys His Ser His Gly Trp Gly Gln Gln Asn Cys Arg 
        755                 760                 765             


His Lys Glu Asp Ala Gly Val Ile Cys Ser Glu Phe Met Ser Leu Arg 
    770                 775                 780                 


Leu Thr Ser Glu Ala Ser Arg Glu Ala Cys Ala Gly Arg Leu Glu Val 
785                 790                 795                 800 


Phe Tyr Asn Gly Ala Trp Gly Thr Val Gly Lys Ser Ser Met Ser Glu 
                805                 810                 815     


Thr Thr Val Gly Val Val Cys Arg Gln Leu Gly Cys Ala Asp Lys Gly 
            820                 825                 830         


Lys Ile Asn Pro Ala Ser Leu Asp Lys Ala Met Ser Ile Pro Met Trp 
        835                 840                 845             


Val Asp Asn Val Gln Cys Pro Lys Gly Pro Asp Thr Leu Trp Gln Cys 
    850                 855                 860                 


Pro Ser Ser Pro Trp Glu Lys Arg Leu Ala Ser Pro Ser Glu Glu Thr 
865                 870                 875                 880 


Trp Ile Thr Cys Asp Asn Lys Ile Arg Leu Gln Glu Gly Pro Thr Ser 
                885                 890                 895     


Cys Ser Gly Arg Val Glu Ile Trp His Gly Gly Ser Trp Gly Thr Val 
            900                 905                 910         


Cys Asp Asp Ser Trp Asp Leu Asp Asp Ala Gln Val Val Cys Gln Gln 
        915                 920                 925             


Leu Gly Cys Gly Pro Ala Leu Lys Ala Phe Lys Glu Ala Glu Phe Gly 
    930                 935                 940                 


Gln Gly Thr Gly Pro Ile Trp Leu Asn Glu Val Lys Cys Lys Gly Asn 
945                 950                 955                 960 


Glu Ser Ser Leu Trp Asp Cys Pro Ala Arg Arg Trp Gly His Ser Glu 
                965                 970                 975     


Cys Gly His Lys Glu Asp Ala Ala Val Asn Cys Thr Asp Ile Ser Val 
            980                 985                 990         


Gln Lys Thr Pro Gln Lys Ala Thr  Thr Gly Arg Ser Ser  Arg Gln Ser 
        995                 1000                 1005             


Ser 
    


<210>  148
<211>  1319
<212>  PRT
<213>  Homo Sapiens

<400>  148

Phe Asn Gly Thr Asp Leu Glu Leu Arg Leu Val Asn Gly Asp Gly Pro 
1               5                   10                  15      


Cys Ser Gly Thr Val Glu Val Lys Phe Gln Gly Gln Trp Gly Thr Val 
            20                  25                  30          


Cys Asp Asp Gly Trp Asn Thr Thr Ala Ser Thr Val Val Cys Lys Gln 
        35                  40                  45              


Leu Gly Cys Pro Phe Ser Phe Ala Met Phe Arg Phe Gly Gln Ala Val 
    50                  55                  60                  


Thr Arg His Gly Lys Ile Trp Leu Asp Asp Val Ser Cys Tyr Gly Asn 
65                  70                  75                  80  


Glu Ser Ala Leu Trp Glu Cys Gln His Arg Glu Trp Gly Ser His Asn 
                85                  90                  95      


Cys Tyr His Gly Glu Asp Val Gly Val Asn Cys Tyr Gly Glu Ala Asn 
            100                 105                 110         


Leu Gly Leu Arg Leu Val Asp Gly Asn Asn Ser Cys Ser Gly Arg Val 
        115                 120                 125             


Glu Val Lys Phe Gln Glu Arg Trp Gly Thr Ile Cys Asp Asp Gly Trp 
    130                 135                 140                 


Asn Leu Asn Thr Ala Ala Val Val Cys Arg Gln Leu Gly Cys Pro Ser 
145                 150                 155                 160 


Ser Phe Ile Ser Ser Gly Val Val Asn Ser Pro Ala Val Leu Arg Pro 
                165                 170                 175     


Ile Trp Leu Asp Asp Ile Leu Cys Gln Gly Asn Glu Leu Ala Leu Trp 
            180                 185                 190         


Asn Cys Arg His Arg Gly Trp Gly Asn His Asp Cys Ser His Asn Glu 
        195                 200                 205             


Asp Val Thr Leu Thr Cys Tyr Asp Ser Ser Asp Leu Glu Leu Arg Leu 
    210                 215                 220                 


Val Gly Gly Thr Asn Arg Cys Met Gly Arg Val Glu Leu Lys Ile Gln 
225                 230                 235                 240 


Gly Arg Trp Gly Thr Val Cys His His Lys Trp Asn Asn Ala Ala Ala 
                245                 250                 255     


Asp Val Val Cys Lys Gln Leu Gly Cys Gly Thr Ala Leu His Phe Ala 
            260                 265                 270         


Gly Leu Pro His Leu Gln Ser Gly Ser Asp Val Val Trp Leu Asp Gly 
        275                 280                 285             


Val Ser Cys Ser Gly Asn Glu Ser Phe Leu Trp Asp Cys Arg His Ser 
    290                 295                 300                 


Gly Thr Val Asn Phe Asp Cys Leu His Gln Asn Asp Val Ser Val Ile 
305                 310                 315                 320 


Cys Ser Asp Gly Ala Asp Leu Glu Leu Arg Leu Ala Asp Gly Ser Asn 
                325                 330                 335     


Asn Cys Ser Gly Arg Val Glu Val Arg Ile His Glu Gln Trp Trp Thr 
            340                 345                 350         


Ile Cys Asp Gln Asn Trp Lys Asn Glu Gln Ala Leu Val Val Cys Lys 
        355                 360                 365             


Gln Leu Gly Cys Pro Phe Ser Val Phe Gly Ser Arg Arg Ala Lys Pro 
    370                 375                 380                 


Ser Asn Glu Ala Arg Asp Ile Trp Ile Asn Ser Ile Ser Cys Thr Gly 
385                 390                 395                 400 


Asn Glu Ser Ala Leu Trp Asp Cys Thr Tyr Asp Gly Lys Ala Lys Arg 
                405                 410                 415     


Thr Cys Phe Arg Arg Ser Asp Ala Gly Val Ile Cys Ser Asp Lys Ala 
            420                 425                 430         


Asp Leu Asp Leu Arg Leu Val Gly Ala His Ser Pro Cys Tyr Gly Arg 
        435                 440                 445             


Leu Glu Val Lys Tyr Gln Gly Glu Trp Gly Thr Val Cys His Asp Arg 
    450                 455                 460                 


Trp Ser Thr Arg Asn Ala Ala Val Val Cys Lys Gln Leu Gly Cys Gly 
465                 470                 475                 480 


Lys Pro Met His Val Phe Gly Met Thr Tyr Phe Lys Glu Ala Ser Gly 
                485                 490                 495     


Pro Ile Trp Leu Asp Asp Val Ser Cys Ile Gly Asn Glu Ser Asn Ile 
            500                 505                 510         


Trp Asp Cys Glu His Ser Gly Trp Gly Lys His Asn Cys Val His Arg 
        515                 520                 525             


Glu Asp Val Ile Val Thr Cys Ser Gly Asp Ala Thr Trp Gly Leu Arg 
    530                 535                 540                 


Leu Val Gly Gly Ser Asn Arg Cys Ser Gly Arg Leu Glu Val Tyr Phe 
545                 550                 555                 560 


Gln Gly Arg Trp Gly Thr Val Cys Asp Asp Gly Trp Asn Ser Lys Ala 
                565                 570                 575     


Ala Ala Val Val Cys Ser Gln Leu Asp Cys Pro Ser Ser Ile Ile Gly 
            580                 585                 590         


Met Gly Leu Gly Asn Ala Ser Thr Gly Tyr Gly Lys Ile Trp Leu Asp 
        595                 600                 605             


Asp Val Ser Cys Asp Gly Asp Glu Ser Asp Leu Trp Ser Cys Arg Asn 
    610                 615                 620                 


Ser Gly Trp Gly Asn Asn Asp Cys Ser His Ser Glu Asp Val Gly Val 
625                 630                 635                 640 


Ile Cys Ser Asp Ala Ser Asp Met Glu Leu Arg Leu Val Gly Gly Ser 
                645                 650                 655     


Ser Arg Cys Ala Gly Lys Val Glu Val Asn Val Gln Gly Ala Val Gly 
            660                 665                 670         


Ile Leu Cys Ala Asn Gly Trp Gly Met Asn Ile Ala Glu Val Val Cys 
        675                 680                 685             


Arg Gln Leu Glu Cys Gly Ser Ala Ile Arg Val Ser Arg Glu Pro His 
    690                 695                 700                 


Phe Thr Glu Arg Thr Leu His Ile Leu Met Ser Asn Ser Gly Cys Thr 
705                 710                 715                 720 


Gly Gly Glu Ala Ser Leu Trp Asp Cys Ile Arg Trp Glu Trp Lys Gln 
                725                 730                 735     


Thr Ala Cys His Leu Asn Met Glu Ala Ser Leu Ile Cys Ser Ala His 
            740                 745                 750         


Arg Gln Pro Arg Leu Val Gly Ala Asp Met Pro Cys Ser Gly Arg Val 
        755                 760                 765             


Glu Val Lys His Ala Asp Thr Trp Arg Ser Val Cys Asp Ser Asp Phe 
    770                 775                 780                 


Ser Leu His Ala Ala Asn Val Leu Cys Arg Glu Leu Asn Cys Gly Asp 
785                 790                 795                 800 


Ala Ile Ser Leu Ser Val Gly Asp His Phe Gly Lys Gly Asn Gly Leu 
                805                 810                 815     


Thr Trp Ala Glu Lys Phe Gln Cys Glu Gly Ser Glu Thr His Leu Ala 
            820                 825                 830         


Leu Cys Pro Ile Val Gln His Pro Glu Asp Thr Cys Ile His Ser Arg 
        835                 840                 845             


Glu Val Gly Val Val Cys Ser Arg Tyr Thr Asp Val Arg Leu Val Asn 
    850                 855                 860                 


Gly Lys Ser Gln Cys Asp Gly Gln Val Glu Ile Asn Val Leu Gly His 
865                 870                 875                 880 


Trp Gly Ser Leu Cys Asp Thr His Trp Asp Pro Glu Asp Ala Arg Val 
                885                 890                 895     


Leu Cys Arg Gln Leu Ser Cys Gly Thr Ala Leu Ser Thr Thr Gly Gly 
            900                 905                 910         


Lys Tyr Ile Gly Glu Arg Ser Val Arg Val Trp Gly His Arg Phe His 
        915                 920                 925             


Cys Leu Gly Asn Glu Ser Leu Leu Asp Asn Cys Gln Met Thr Val Leu 
    930                 935                 940                 


Gly Ala Pro Pro Cys Ile His Gly Asn Thr Val Ser Val Ile Cys Thr 
945                 950                 955                 960 


Gly Ser Leu Thr Gln Pro Leu Phe Pro Cys Leu Ala Asn Val Ser Asp 
                965                 970                 975     


Pro Tyr Leu Ser Ala Val Pro Glu Gly Ser Ala Leu Ile Cys Leu Glu 
            980                 985                 990         


Asp Lys Arg Leu Arg Leu Val Asp  Gly Asp Ser Arg Cys  Ala Gly Arg 
        995                 1000                 1005             


Val Glu  Ile Tyr His Asp Gly  Phe Trp Gly Thr Ile  Cys Asp Asp 
    1010                 1015                 1020             


Gly Trp  Asp Leu Ser Asp Ala  His Val Val Cys Gln  Lys Leu Gly 
    1025                 1030                 1035             


Cys Gly  Val Ala Phe Asn Ala  Thr Val Ser Ala His  Phe Gly Glu 
    1040                 1045                 1050             


Gly Ser  Gly Pro Ile Trp Leu  Asp Asp Leu Asn Cys  Thr Gly Met 
    1055                 1060                 1065             


Glu Ser  His Leu Trp Gln Cys  Pro Ser Arg Gly Trp  Gly Gln His 
    1070                 1075                 1080             


Asp Cys  Arg His Lys Glu Asp  Ala Gly Val Ile Cys  Ser Glu Phe 
    1085                 1090                 1095             


Thr Ala  Leu Arg Leu Tyr Ser  Glu Thr Glu Thr Glu  Ser Cys Ala 
    1100                 1105                 1110             


Gly Arg  Leu Glu Val Phe Tyr  Asn Gly Thr Trp Gly  Ser Val Gly 
    1115                 1120                 1125             


Arg Arg  Asn Ile Thr Thr Ala  Ile Ala Gly Ile Val  Cys Arg Gln 
    1130                 1135                 1140             


Leu Gly  Cys Gly Glu Asn Gly  Val Val Ser Leu Ala  Pro Leu Ser 
    1145                 1150                 1155             


Lys Thr  Gly Ser Gly Phe Met  Trp Val Asp Asp Ile  Gln Cys Pro 
    1160                 1165                 1170             


Lys Thr  His Ile Ser Ile Trp  Gln Cys Leu Ser Ala  Pro Trp Glu 
    1175                 1180                 1185             


Arg Arg  Ile Ser Ser Pro Ala  Glu Glu Thr Trp Ile  Thr Cys Glu 
    1190                 1195                 1200             


Asp Arg  Ile Arg Val Arg Gly  Gly Asp Thr Glu Cys  Ser Gly Arg 
    1205                 1210                 1215             


Val Glu  Ile Trp His Ala Gly  Ser Trp Gly Thr Val  Cys Asp Asp 
    1220                 1225                 1230             


Ser Trp  Asp Leu Ala Glu Ala  Glu Val Val Cys Gln  Gln Leu Gly 
    1235                 1240                 1245             


Cys Gly  Ser Ala Leu Ala Ala  Leu Arg Asp Ala Ser  Phe Gly Gln 
    1250                 1255                 1260             


Gly Thr  Gly Thr Ile Trp Leu  Asp Asp Met Arg Cys  Lys Gly Asn 
    1265                 1270                 1275             


Glu Ser  Phe Leu Trp Asp Cys  His Ala Lys Pro Trp  Gly Gln Ser 
    1280                 1285                 1290             


Asp Cys  Gly His Lys Glu Asp  Ala Gly Val Arg Cys  Ser Gly Gln 
    1295                 1300                 1305             


Ser Leu  Lys Ser Leu Asn Ala  Ser Ser Gly His 
    1310                 1315                 


<210>  149
<211>  603
<212>  PRT
<213>  Homo Sapiens

<400>  149

Trp Asp Gln Met Cys Ile Glu Lys Glu Ala Asn Lys Thr Tyr Asn Cys 
1               5                   10                  15      


Glu Asn Leu Gly Leu Ser Glu Ile Pro Asp Thr Leu Pro Asn Thr Thr 
            20                  25                  30          


Glu Phe Leu Glu Phe Ser Phe Asn Phe Leu Pro Thr Ile His Asn Arg 
        35                  40                  45              


Thr Phe Ser Arg Leu Met Asn Leu Thr Phe Leu Asp Leu Thr Arg Cys 
    50                  55                  60                  


Gln Ile Asn Trp Ile His Glu Asp Thr Phe Gln Ser His His Gln Leu 
65                  70                  75                  80  


Ser Thr Leu Val Leu Thr Gly Asn Pro Leu Ile Phe Met Ala Glu Thr 
                85                  90                  95      


Ser Leu Asn Gly Pro Lys Ser Leu Lys His Leu Phe Leu Ile Gln Thr 
            100                 105                 110         


Gly Ile Ser Asn Leu Glu Phe Ile Pro Val His Asn Leu Glu Asn Leu 
        115                 120                 125             


Glu Ser Leu Tyr Leu Gly Ser Asn His Ile Ser Ser Ile Lys Phe Pro 
    130                 135                 140                 


Lys Asp Phe Pro Ala Arg Asn Leu Lys Val Leu Asp Phe Gln Asn Asn 
145                 150                 155                 160 


Ala Ile His Tyr Ile Ser Arg Glu Asp Met Arg Ser Leu Glu Gln Ala 
                165                 170                 175     


Ile Asn Leu Ser Leu Asn Phe Asn Gly Asn Asn Val Lys Gly Ile Glu 
            180                 185                 190         


Leu Gly Ala Phe Asp Ser Thr Val Phe Gln Ser Leu Asn Phe Gly Gly 
        195                 200                 205             


Thr Pro Asn Leu Ser Val Ile Phe Asn Gly Leu Gln Asn Ser Thr Thr 
    210                 215                 220                 


Gln Ser Leu Trp Leu Gly Thr Phe Glu Asp Ile Asp Asp Glu Asp Ile 
225                 230                 235                 240 


Ser Ser Ala Met Leu Lys Gly Leu Cys Glu Met Ser Val Glu Ser Leu 
                245                 250                 255     


Asn Leu Gln Glu His Arg Phe Ser Asp Ile Ser Ser Thr Thr Phe Gln 
            260                 265                 270         


Cys Phe Thr Gln Leu Gln Glu Leu Asp Leu Thr Ala Thr His Leu Lys 
        275                 280                 285             


Gly Leu Pro Ser Gly Met Lys Gly Leu Asn Leu Leu Lys Lys Leu Val 
    290                 295                 300                 


Leu Ser Val Asn His Phe Asp Gln Leu Cys Gln Ile Ser Ala Ala Asn 
305                 310                 315                 320 


Phe Pro Ser Leu Thr His Leu Tyr Ile Arg Gly Asn Val Lys Lys Leu 
                325                 330                 335     


His Leu Gly Val Gly Cys Leu Glu Lys Leu Gly Asn Leu Gln Thr Leu 
            340                 345                 350         


Asp Leu Ser His Asn Asp Ile Glu Ala Ser Asp Cys Cys Ser Leu Gln 
        355                 360                 365             


Leu Lys Asn Leu Ser His Leu Gln Thr Leu Asn Leu Ser His Asn Glu 
    370                 375                 380                 


Pro Leu Gly Leu Gln Ser Gln Ala Phe Lys Glu Cys Pro Gln Leu Glu 
385                 390                 395                 400 


Leu Leu Asp Leu Ala Phe Thr Arg Leu His Ile Asn Ala Pro Gln Ser 
                405                 410                 415     


Pro Phe Gln Asn Leu His Phe Leu Gln Val Leu Asn Leu Thr Tyr Cys 
            420                 425                 430         


Phe Leu Asp Thr Ser Asn Gln His Leu Leu Ala Gly Leu Pro Val Leu 
        435                 440                 445             


Arg His Leu Asn Leu Lys Gly Asn His Phe Gln Asp Gly Thr Ile Thr 
    450                 455                 460                 


Lys Thr Asn Leu Leu Gln Thr Val Gly Ser Leu Glu Val Leu Ile Leu 
465                 470                 475                 480 


Ser Ser Cys Gly Leu Leu Ser Ile Asp Gln Gln Ala Phe His Ser Leu 
                485                 490                 495     


Gly Lys Met Ser His Val Asp Leu Ser His Asn Ser Leu Thr Cys Asp 
            500                 505                 510         


Ser Ile Asp Ser Leu Ser His Leu Lys Gly Ile Tyr Leu Asn Leu Ala 
        515                 520                 525             


Ala Asn Ser Ile Asn Ile Ile Ser Pro Arg Leu Leu Pro Ile Leu Ser 
    530                 535                 540                 


Gln Gln Ser Thr Ile Asn Leu Ser His Asn Pro Leu Asp Cys Thr Cys 
545                 550                 555                 560 


Ser Asn Ile His Phe Leu Thr Trp Tyr Lys Glu Asn Leu His Lys Leu 
                565                 570                 575     


Glu Gly Ser Glu Glu Thr Thr Cys Ala Asn Pro Pro Ser Leu Arg Gly 
            580                 585                 590         


Val Lys Leu Ser Asp Val Lys Leu Ser Cys Gly 
        595                 600             


<210>  150
<211>  272
<212>  PRT
<213>  Homo Sapiens

<400>  150

Pro Glu Glu Pro Leu Val Val Lys Val Glu Glu Gly Asp Asn Ala Val 
1               5                   10                  15      


Leu Gln Cys Leu Lys Gly Thr Ser Asp Gly Pro Thr Gln Gln Leu Thr 
            20                  25                  30          


Trp Ser Arg Glu Ser Pro Leu Lys Pro Phe Leu Lys Leu Ser Leu Gly 
        35                  40                  45              


Leu Pro Gly Leu Gly Ile His Met Arg Pro Leu Ala Ile Trp Leu Phe 
    50                  55                  60                  


Ile Phe Asn Val Ser Gln Gln Met Gly Gly Phe Tyr Leu Cys Gln Pro 
65                  70                  75                  80  


Gly Pro Pro Ser Glu Lys Ala Trp Gln Pro Gly Trp Thr Val Asn Val 
                85                  90                  95      


Glu Gly Ser Gly Glu Leu Phe Arg Trp Asn Val Ser Asp Leu Gly Gly 
            100                 105                 110         


Leu Gly Cys Gly Leu Lys Asn Arg Ser Ser Glu Gly Pro Ser Ser Pro 
        115                 120                 125             


Ser Gly Lys Leu Met Ser Pro Lys Leu Tyr Val Trp Ala Lys Asp Arg 
    130                 135                 140                 


Pro Glu Ile Trp Glu Gly Glu Pro Pro Cys Leu Pro Pro Arg Asp Ser 
145                 150                 155                 160 


Leu Asn Gln Ser Leu Ser Gln Asp Leu Thr Met Ala Pro Gly Ser Thr 
                165                 170                 175     


Leu Trp Leu Ser Cys Gly Val Pro Pro Asp Ser Val Ser Arg Gly Pro 
            180                 185                 190         


Leu Ser Trp Thr His Val His Pro Lys Gly Pro Lys Ser Leu Leu Ser 
        195                 200                 205             


Leu Glu Leu Lys Asp Asp Arg Pro Ala Arg Asp Met Trp Val Met Glu 
    210                 215                 220                 


Thr Gly Leu Leu Leu Pro Arg Ala Thr Ala Gln Asp Ala Gly Lys Tyr 
225                 230                 235                 240 


Tyr Cys His Arg Gly Asn Leu Thr Met Ser Phe His Leu Glu Ile Thr 
                245                 250                 255     


Ala Arg Pro Val Leu Trp His Trp Leu Leu Arg Thr Gly Gly Trp Lys 
            260                 265                 270         


<210>  151
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  151

Leu Lys Glu Pro Leu Ser Phe His Val Ile Trp Ile Ala Ser Phe Tyr 
1               5                   10                  15      


Asn His Ser Trp Lys Gln Asn Leu Val Ser Gly Trp Leu Ser Asp Leu 
            20                  25                  30          


Gln Thr His Thr Trp Asp Ser Asn Ser Ser Thr Ile Val Phe Leu Trp 
        35                  40                  45              


Pro Trp Ser Arg Gly Asn Phe Ser Asn Glu Glu Trp Lys Glu Leu Glu 
    50                  55                  60                  


Thr Leu Phe Arg Ile Arg Thr Ile Arg Ser Phe Glu Gly Ile Arg Arg 
65                  70                  75                  80  


Tyr Ala His Glu Leu Gln Phe Glu Tyr Pro Phe Glu Ile Gln Val Thr 
                85                  90                  95      


Gly Gly Cys Glu Leu His Ser Gly Lys Val Ser Gly Ser Phe Leu Gln 
            100                 105                 110         


Leu Ala Tyr Gln Gly Ser Asp Phe Val Ser Phe Gln Asn Asn Ser Trp 
        115                 120                 125             


Leu Pro Tyr Pro Val Ala Gly Asn Met Ala Lys His Phe Cys Lys Val 
    130                 135                 140                 


Leu Asn Gln Asn Gln His Glu Asn Asp Ile Thr His Asn Leu Leu Ser 
145                 150                 155                 160 


Asp Thr Cys Pro Arg Phe Ile Leu Gly Leu Leu Asp Ala Gly Lys Ala 
                165                 170                 175     


His Leu Gln Arg Gln Val Lys Pro Glu Ala Trp Leu Ser His Gly Pro 
            180                 185                 190         


Ser Pro Gly Pro Gly His Leu Gln Leu Val Cys His Val Ser Gly Phe 
        195                 200                 205             


Tyr Pro Lys Pro Val Trp Val Met Trp Met Arg Gly Glu Gln Glu Gln 
    210                 215                 220                 


Gln Gly Thr Gln Arg Gly Asp Ile Leu Pro Ser Ala Asp Gly Thr Trp 
225                 230                 235                 240 


Tyr Leu Arg Ala Thr Leu Glu Val Ala Ala Gly Glu Ala Ala Asp Leu 
                245                 250                 255     


Ser Cys Arg Val Lys His Ser Ser Leu Glu Gly Gln Asp Ile Val Leu 
            260                 265                 270         


Tyr Trp Glu His His Ser Ser Val 
        275                 280 


<210>  152
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  152

Ser Glu His Ala Phe Gln Gly Pro Thr Ser Phe His Val Ile Gln Thr 
1               5                   10                  15      


Ser Ser Phe Thr Asn Ser Thr Trp Ala Gln Thr Gln Gly Ser Gly Trp 
            20                  25                  30          


Leu Asp Asp Leu Gln Ile His Gly Trp Asp Ser Asp Ser Gly Thr Ala 
        35                  40                  45              


Ile Phe Leu Lys Pro Trp Ser Lys Gly Asn Phe Ser Asp Lys Glu Val 
    50                  55                  60                  


Ala Glu Leu Glu Glu Ile Phe Arg Val Tyr Ile Phe Gly Phe Ala Arg 
65                  70                  75                  80  


Glu Val Gln Asp Phe Ala Gly Asp Phe Gln Met Lys Tyr Pro Phe Glu 
                85                  90                  95      


Ile Gln Gly Ile Ala Gly Cys Glu Leu His Ser Gly Gly Ala Ile Val 
            100                 105                 110         


Ser Phe Leu Arg Gly Ala Leu Gly Gly Leu Asp Phe Leu Ser Val Lys 
        115                 120                 125             


Asn Ala Ser Cys Val Pro Ser Pro Glu Gly Gly Ser Arg Ala Gln Lys 
    130                 135                 140                 


Phe Cys Ala Leu Ile Ile Gln Tyr Gln Gly Ile Met Glu Thr Val Arg 
145                 150                 155                 160 


Ile Leu Leu Tyr Glu Thr Cys Pro Arg Tyr Leu Leu Gly Val Leu Asn 
                165                 170                 175     


Ala Gly Lys Ala Asp Leu Gln Arg Gln Val Lys Pro Glu Ala Trp Leu 
            180                 185                 190         


Ser Ser Gly Pro Ser Pro Gly Pro Gly Arg Leu Gln Leu Val Cys His 
        195                 200                 205             


Val Ser Gly Phe Tyr Pro Lys Pro Val Trp Val Met Trp Met Arg Gly 
    210                 215                 220                 


Glu Gln Glu Gln Gln Gly Thr Gln Leu Gly Asp Ile Leu Pro Asn Ala 
225                 230                 235                 240 


Asn Trp Thr Trp Tyr Leu Arg Ala Thr Leu Asp Val Ala Asp Gly Glu 
                245                 250                 255     


Ala Ala Gly Leu Ser Cys Arg Val Lys His Ser Ser Leu Glu Gly Gln 
            260                 265                 270         


Asp Ile Ile Leu Tyr Trp Arg Asn Pro Thr Ser Ile Gly Ser 
        275                 280                 285     


<210>  153
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  153

Asn Ala Asp Ala Ser Gln Glu His Val Ser Phe His Val Ile Gln Ile 
1               5                   10                  15      


Phe Ser Phe Val Asn Gln Ser Trp Ala Arg Gly Gln Gly Ser Gly Trp 
            20                  25                  30          


Leu Asp Glu Leu Gln Thr His Gly Trp Asp Ser Glu Ser Gly Thr Ile 
        35                  40                  45              


Ile Phe Leu His Asn Trp Ser Lys Gly Asn Phe Ser Asn Glu Glu Leu 
    50                  55                  60                  


Ser Asp Leu Glu Leu Leu Phe Arg Phe Tyr Leu Phe Gly Leu Thr Arg 
65                  70                  75                  80  


Glu Ile Gln Asp His Ala Ser Gln Asp Tyr Ser Lys Tyr Pro Phe Glu 
                85                  90                  95      


Val Gln Val Lys Ala Gly Cys Glu Leu His Ser Gly Lys Ser Pro Glu 
            100                 105                 110         


Gly Phe Phe Gln Val Ala Phe Asn Gly Leu Asp Leu Leu Ser Phe Gln 
        115                 120                 125             


Asn Thr Thr Trp Val Pro Ser Pro Gly Cys Gly Ser Leu Ala Gln Ser 
    130                 135                 140                 


Val Cys His Leu Leu Asn His Gln Tyr Glu Gly Val Thr Glu Thr Val 
145                 150                 155                 160 


Tyr Asn Leu Ile Arg Ser Thr Cys Pro Arg Phe Leu Leu Gly Leu Leu 
                165                 170                 175     


Asp Ala Gly Lys Met Tyr Val His Arg Gln Val Arg Pro Glu Ala Trp 
            180                 185                 190         


Leu Ser Ser Arg Pro Ser Leu Gly Ser Gly Gln Leu Leu Leu Val Cys 
        195                 200                 205             


His Ala Ser Gly Phe Tyr Pro Lys Pro Val Trp Val Thr Trp Met Arg 
    210                 215                 220                 


Asn Glu Gln Glu Gln Leu Gly Thr Lys His Gly Asp Ile Leu Pro Asn 
225                 230                 235                 240 


Ala Asp Gly Thr Trp Tyr Leu Gln Val Ile Leu Glu Val Ala Ser Glu 
                245                 250                 255     


Glu Pro Ala Gly Leu Ser Cys Arg Val Arg His Ser Ser Leu Gly Gly 
            260                 265                 270         


Gln Asp Ile Ile Leu Tyr Trp Gly His His Phe Ser Met 
        275                 280                 285 


<210>  154
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  154

Glu Val Pro Gln Arg Leu Phe Pro Leu Arg Cys Leu Gln Ile Ser Ser 
1               5                   10                  15      


Phe Ala Asn Ser Ser Trp Thr Arg Thr Asp Gly Leu Ala Trp Leu Gly 
            20                  25                  30          


Glu Leu Gln Thr His Ser Trp Ser Asn Asp Ser Asp Thr Val Arg Ser 
        35                  40                  45              


Leu Lys Pro Trp Ser Gln Gly Thr Phe Ser Asp Gln Gln Trp Glu Thr 
    50                  55                  60                  


Leu Gln His Ile Phe Arg Val Tyr Arg Ser Ser Phe Thr Arg Asp Val 
65                  70                  75                  80  


Lys Glu Phe Ala Lys Met Leu Arg Leu Ser Tyr Pro Leu Glu Leu Gln 
                85                  90                  95      


Val Ser Ala Gly Cys Glu Val His Pro Gly Asn Ala Ser Asn Asn Phe 
            100                 105                 110         


Phe His Val Ala Phe Gln Gly Lys Asp Ile Leu Ser Phe Gln Gly Thr 
        115                 120                 125             


Ser Trp Glu Pro Thr Gln Glu Ala Pro Leu Trp Val Asn Leu Ala Ile 
    130                 135                 140                 


Gln Val Leu Asn Gln Asp Lys Trp Thr Arg Glu Thr Val Gln Trp Leu 
145                 150                 155                 160 


Leu Asn Gly Thr Cys Pro Gln Phe Val Ser Gly Leu Leu Glu Ser Gly 
                165                 170                 175     


Lys Ser Glu Leu Lys Lys Gln Val Lys Pro Lys Ala Trp Leu Ser Arg 
            180                 185                 190         


Gly Pro Ser Pro Gly Pro Gly Arg Leu Leu Leu Val Cys His Val Ser 
        195                 200                 205             


Gly Phe Tyr Pro Lys Pro Val Trp Val Lys Trp Met Arg Gly Glu Gln 
    210                 215                 220                 


Glu Gln Gln Gly Thr Gln Pro Gly Asp Ile Leu Pro Asn Ala Asp Glu 
225                 230                 235                 240 


Thr Trp Tyr Leu Arg Ala Thr Leu Asp Val Val Ala Gly Glu Ala Ala 
                245                 250                 255     


Gly Leu Ser Cys Arg Val Lys His Ser Ser Leu Glu Gly Gln Asp Ile 
            260                 265                 270         


Val Leu Tyr Trp Gly Gly Ser Tyr Thr Ser 
        275                 280         


<210>  155
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  155

Ala Pro Gln Ala Leu Gln Ser Tyr His Leu Ala Ala Glu Glu Gln Leu 
1               5                   10                  15      


Ser Phe Arg Met Leu Gln Thr Ser Ser Phe Ala Asn His Ser Trp Ala 
            20                  25                  30          


His Ser Glu Gly Ser Gly Trp Leu Gly Asp Leu Gln Thr His Gly Trp 
        35                  40                  45              


Asp Thr Val Leu Gly Thr Ile Arg Phe Leu Lys Pro Trp Ser His Gly 
    50                  55                  60                  


Asn Phe Ser Lys Gln Glu Leu Lys Asn Leu Gln Ser Leu Phe Gln Leu 
65                  70                  75                  80  


Tyr Phe His Ser Phe Ile Gln Ile Val Gln Ala Ser Ala Gly Gln Phe 
                85                  90                  95      


Gln Leu Glu Tyr Pro Phe Glu Ile Gln Ile Leu Ala Gly Cys Arg Met 
            100                 105                 110         


Asn Ala Pro Gln Ile Phe Leu Asn Met Ala Tyr Gln Gly Ser Asp Phe 
        115                 120                 125             


Leu Ser Phe Gln Gly Ile Ser Trp Glu Pro Ser Pro Gly Ala Gly Ile 
    130                 135                 140                 


Arg Ala Gln Asn Ile Cys Lys Val Leu Asn Arg Tyr Leu Asp Ile Lys 
145                 150                 155                 160 


Glu Ile Leu Gln Ser Leu Leu Gly His Thr Cys Pro Arg Phe Leu Ala 
                165                 170                 175     


Gly Leu Met Glu Ala Gly Glu Ser Glu Leu Lys Arg Lys Val Lys Pro 
            180                 185                 190         


Glu Ala Trp Leu Ser Cys Gly Pro Ser Pro Gly Pro Gly Arg Leu Gln 
        195                 200                 205             


Leu Val Cys His Val Ser Gly Phe Tyr Pro Lys Pro Val Trp Val Met 
    210                 215                 220                 


Trp Met Arg Gly Glu Gln Glu Gln Arg Gly Thr Gln Arg Gly Asp Val 
225                 230                 235                 240 


Leu Pro Asn Ala Asp Glu Thr Trp Tyr Leu Arg Ala Thr Leu Asp Val 
                245                 250                 255     


Ala Ala Gly Glu Ala Ala Gly Leu Ser Cys Arg Val Lys His Ser Ser 
            260                 265                 270         


Leu Gly Gly His Asp Leu Ile Ile His Trp Gly Gly Tyr 
        275                 280                 285 


<210>  156
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  156

Lys Glu Ile Thr Asn Ala Leu Glu Thr Trp Gly Ala Leu Gly Gln Asp 
1               5                   10                  15      


Ile Asn Leu Asp Ile Pro Ser Phe Gln Met Ser Asp Asp Ile Asp Asp 
            20                  25                  30          


Ile Lys Trp Glu Lys Thr Ser Asp Lys Lys Lys Ile Ala Gln Phe Arg 
        35                  40                  45              


Lys Glu Lys Glu Thr Phe Lys Glu Lys Asp Thr Tyr Lys Leu Phe Lys 
    50                  55                  60                  


Asn Gly Thr Leu Lys Ile Lys His Leu Lys Thr Asp Asp Gln Asp Ile 
65                  70                  75                  80  


Tyr Lys Val Ser Ile Tyr Asp Thr Lys Gly Lys Asn Val Leu Glu Lys 
                85                  90                  95      


Ile Phe Asp Leu Lys Ile Gln Glu Arg Val Ser Lys Pro Lys Ile Ser 
            100                 105                 110         


Trp Thr Cys Ile Asn Thr Thr Leu Thr Cys Glu Val Met Asn Gly Thr 
        115                 120                 125             


Asp Pro Glu Leu Asn Leu Tyr Gln Asp Gly Lys His Leu Lys Leu Ser 
    130                 135                 140                 


Gln Arg Val Ile Thr His Lys Trp Thr Thr Ser Leu Ser Ala Lys Phe 
145                 150                 155                 160 


Lys Cys Thr Ala Gly Asn Lys Val Ser Lys Glu Ser Ser Val Glu Pro 
                165                 170                 175     


Val Ser Cys Pro Glu Lys Gly Leu Asp 
            180                 185 


<210>  157
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  157

Gln Val Gln Val Val Thr Gln Asp Glu Arg Glu Gln Leu Tyr Thr Pro 
1               5                   10                  15      


Ala Ser Leu Lys Cys Ser Leu Gln Asn Ala Gln Glu Ala Leu Ile Val 
            20                  25                  30          


Thr Trp Gln Lys Lys Lys Ala Val Ser Pro Glu Asn Met Val Thr Phe 
        35                  40                  45              


Ser Glu Asn His Gly Val Val Ile Gln Pro Ala Tyr Lys Asp Lys Ile 
    50                  55                  60                  


Asn Ile Thr Gln Leu Gly Leu Gln Asn Ser Thr Ile Thr Phe Trp Asn 
65                  70                  75                  80  


Ile Thr Leu Glu Asp Glu Gly Cys Tyr Met Cys Leu Phe Asn Thr Phe 
                85                  90                  95      


Gly Phe Gly Lys Ile Ser Gly Thr Ala Cys Leu Thr Val Tyr Val Gln 
            100                 105                 110         


Pro Ile Val Ser Leu His Tyr Lys Phe Ser Glu Asp His Leu Asn Ile 
        115                 120                 125             


Thr Cys Ser Ala Thr Ala Arg Pro Ala Pro Met Val Phe Trp Lys Val 
    130                 135                 140                 


Pro Arg Ser Gly Ile Glu Asn Ser Thr Val Thr Leu Ser His Pro Asn 
145                 150                 155                 160 


Gly Thr Thr Ser Val Thr Ser Ile Leu His Ile Lys Asp Pro Lys Asn 
                165                 170                 175     


Gln Val Gly Lys Glu Val Ile Cys Gln Val Leu His Leu Gly Thr Val 
            180                 185                 190         


Thr Asp Phe Lys Gln Thr Val Asn Lys Gly 
        195                 200         


<210>  158
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  158

Met Asp Glu Lys Gln Ile Thr Gln Asn Tyr Ser Lys Val Leu Ala Glu 
1               5                   10                  15      


Val Asn Thr Ser Trp Pro Val Lys Met Ala Thr Asn Ala Val Leu Cys 
            20                  25                  30          


Cys Pro Pro Ile Ala Leu Arg Asn Leu Ile Ile Ile Thr Trp Glu Ile 
        35                  40                  45              


Ile Leu Arg Gly Gln Pro Ser Cys Thr Lys Ala Tyr Lys Lys Glu Thr 
    50                  55                  60                  


Asn Glu Thr Lys Glu Thr Asn Cys Thr Asp Glu Arg Ile Thr Trp Val 
65                  70                  75                  80  


Ser Arg Pro Asp Gln Asn Ser Asp Leu Gln Ile Arg Thr Val Ala Ile 
                85                  90                  95      


Thr His Asp Gly Tyr Tyr Arg Cys Ile Met Val Thr Pro Asp Gly Asn 
            100                 105                 110         


Phe His Arg Gly Tyr His Leu Gln Val Leu Val Thr Pro Glu Val Thr 
        115                 120                 125             


Leu Phe Gln Asn Arg Asn Arg Thr Ala Val Cys Lys Ala Val Ala Gly 
    130                 135                 140                 


Lys Pro Ala Ala His Ile Ser Trp Ile Pro Glu Gly Asp Cys Ala Thr 
145                 150                 155                 160 


Lys Gln Glu Tyr Trp Ser Asn Gly Thr Val Thr Val Lys Ser Thr Cys 
                165                 170                 175     


His Trp Glu Val His Asn Val Ser Thr Val Thr Cys His Val Ser His 
            180                 185                 190         


Leu Thr Gly Asn Lys Ser Leu Tyr Ile Glu Leu Leu Pro Val Pro Gly 
        195                 200                 205             


Ala Lys Lys Ser Ala Lys Leu 
    210                 215 


<210>  159
<211>  87
<212>  PRT
<213>  Homo Sapiens

<400>  159

Met Asp Ile Asn Ala Val Leu Cys Cys Pro Pro Ile Ala Leu Arg Asn 
1               5                   10                  15      


Leu Ile Ile Ile Thr Trp Glu Ile Ile Leu Arg Gly Gln Pro Ser Cys 
            20                  25                  30          


Thr Lys Ala Tyr Lys Lys Glu Thr Asn Glu Thr Lys Glu Thr Asn Cys 
        35                  40                  45              


Thr Val Glu Arg Ile Thr Trp Val Ser Arg Pro Asp Gln Asn Ser Asp 
    50                  55                  60                  


Leu Gln Ile Arg Pro Val Asp Thr Thr His Asp Gly Tyr Tyr Arg Gly 
65                  70                  75                  80  


Ile Val Val Thr Pro Asp Gly 
                85          


<210>  160
<211>  264
<212>  PRT
<213>  Homo Sapiens

<400>  160

Pro Arg Phe Met Gly Thr Ile Ser Asp Val Lys Thr Asn Val Gln Leu 
1               5                   10                  15      


Leu Lys Gly Arg Val Asp Asn Ile Ser Thr Leu Asp Ser Glu Ile Lys 
            20                  25                  30          


Lys Asn Ser Asp Gly Met Glu Ala Ala Gly Val Gln Ile Gln Met Val 
        35                  40                  45              


Asn Glu Ser Leu Gly Tyr Val Arg Ser Gln Phe Leu Lys Leu Lys Thr 
    50                  55                  60                  


Ser Val Glu Lys Ala Asn Ala Gln Ile Gln Ile Leu Thr Arg Ser Trp 
65                  70                  75                  80  


Glu Glu Val Ser Thr Leu Asn Ala Gln Ile Pro Glu Leu Lys Ser Asp 
                85                  90                  95      


Leu Glu Lys Ala Ser Ala Leu Asn Thr Lys Ile Arg Ala Leu Gln Gly 
            100                 105                 110         


Ser Leu Glu Asn Met Ser Lys Leu Leu Lys Arg Gln Asn Asp Ile Leu 
        115                 120                 125             


Gln Val Val Ser Gln Gly Trp Lys Tyr Phe Lys Gly Asn Phe Tyr Tyr 
    130                 135                 140                 


Phe Ser Leu Ile Pro Lys Thr Trp Tyr Ser Ala Glu Gln Phe Cys Val 
145                 150                 155                 160 


Ser Arg Asn Ser His Leu Thr Ser Val Thr Ser Glu Ser Glu Gln Glu 
                165                 170                 175     


Phe Leu Tyr Lys Thr Ala Gly Gly Leu Ile Tyr Trp Ile Gly Leu Thr 
            180                 185                 190         


Lys Ala Gly Met Glu Gly Asp Trp Ser Trp Val Asp Asp Thr Pro Phe 
        195                 200                 205             


Asn Lys Val Gln Ser Ala Arg Phe Trp Ile Pro Gly Glu Pro Asn Asn 
    210                 215                 220                 


Ala Gly Asn Asn Glu His Cys Gly Asn Ile Lys Ala Pro Ser Leu Gln 
225                 230                 235                 240 


Ala Trp Asn Asp Ala Pro Cys Asp Lys Thr Phe Leu Phe Ile Cys Lys 
                245                 250                 255     


Arg Pro Tyr Val Pro Ser Glu Pro 
            260                 


<210>  161
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  161

Ala Val Ser Lys Val Pro Ser Ser Ile Ser Gln Glu Gln Ser Arg Gln 
1               5                   10                  15      


Asp Ala Ile Tyr Gln Asn Leu Thr Gln Leu Lys Ala Ala Val Gly Glu 
            20                  25                  30          


Leu Ser Glu Lys Ser Lys Leu Gln Glu Ile Tyr Gln Glu Leu Thr Gln 
        35                  40                  45              


Leu Lys Ala Ala Val Gly Glu Leu Pro Glu Lys Ser Lys Leu Gln Glu 
    50                  55                  60                  


Ile Tyr Gln Glu Leu Thr Arg Leu Lys Ala Ala Val Gly Glu Leu Pro 
65                  70                  75                  80  


Glu Lys Ser Lys Leu Gln Glu Ile Tyr Gln Glu Leu Thr Trp Leu Lys 
                85                  90                  95      


Ala Ala Val Gly Glu Leu Pro Glu Lys Ser Lys Met Gln Glu Ile Tyr 
            100                 105                 110         


Gln Glu Leu Thr Arg Leu Lys Ala Ala Val Gly Glu Leu Pro Glu Lys 
        115                 120                 125             


Ser Lys Gln Gln Glu Ile Tyr Gln Glu Leu Thr Arg Leu Lys Ala Ala 
    130                 135                 140                 


Val Gly Glu Leu Pro Glu Lys Ser Lys Gln Gln Glu Ile Tyr Gln Glu 
145                 150                 155                 160 


Leu Thr Arg Leu Lys Ala Ala Val Gly Glu Leu Pro Glu Lys Ser Lys 
                165                 170                 175     


Gln Gln Glu Ile Tyr Gln Glu Leu Thr Gln Leu Lys Ala Ala Val Glu 
            180                 185                 190         


Arg Leu Cys His Pro Cys Pro Trp Glu Trp Thr Phe Phe Gln Gly Asn 
        195                 200                 205             


Cys Tyr Phe Met Ser Asn Ser Gln Arg Asn Trp His Asp Ser Ile Thr 
    210                 215                 220                 


Ala Cys Lys Glu Val Gly Ala Gln Leu Val Val Ile Lys Ser Ala Glu 
225                 230                 235                 240 


Glu Gln Asn Phe Leu Gln Leu Gln Ser Ser Arg Ser Asn Arg Phe Thr 
                245                 250                 255     


Trp Met Gly Leu Ser Asp Leu Asn Gln Glu Gly Thr Trp Gln Trp Val 
            260                 265                 270         


Asp Gly Ser Pro Leu Leu Pro Ser Phe Lys Gln Tyr Trp Asn Arg Gly 
        275                 280                 285             


Glu Pro Asn Asn Val Gly Glu Glu Asp Cys Ala Glu Phe Ser Gly Asn 
    290                 295                 300                 


Gly Trp Asn Asp Asp Lys Cys Asn Leu Ala Lys Phe Trp Ile Cys Lys 
305                 310                 315                 320 


Lys Ser Ala Ala Ser Cys Ser Arg Asp Glu Glu Gln Phe Leu Ser Pro 
                325                 330                 335     


Ala Pro Ala Thr Pro Asn Pro 
            340             


<210>  162
<211>  515
<212>  PRT
<213>  Homo Sapiens

<400>  162

Met Ser Leu Trp Leu Leu Glu Gly Val Pro Met Arg Gln Ala Ala Val 
1               5                   10                  15      


Thr Ser Thr Ser Leu Thr Ile Lys Ser Val Phe Thr Arg Ser Glu Leu 
            20                  25                  30          


Lys Phe Ser Pro Gln Trp Ser His His Gly Lys Ile Val Thr Cys Gln 
        35                  40                  45              


Leu Gln Asp Ala Asp Gly Lys Phe Leu Ser Asn Asp Thr Val Gln Leu 
    50                  55                  60                  


Asn Val Lys His Thr Pro Lys Leu Glu Ile Lys Val Thr Pro Ser Asp 
65                  70                  75                  80  


Ala Ile Val Arg Glu Gly Asp Ser Val Thr Met Thr Cys Glu Val Ser 
                85                  90                  95      


Ser Ser Asn Pro Glu Tyr Thr Thr Val Ser Trp Leu Lys Asp Gly Thr 
            100                 105                 110         


Ser Leu Lys Lys Gln Asn Thr Phe Thr Leu Asn Leu Arg Glu Val Thr 
        115                 120                 125             


Lys Asp Gln Ser Gly Lys Tyr Cys Cys Gln Val Ser Asn Asp Val Gly 
    130                 135                 140                 


Pro Gly Arg Ser Glu Glu Val Phe Leu Gln Val Gln Tyr Ala Pro Glu 
145                 150                 155                 160 


Pro Ser Thr Val Gln Ile Leu His Ser Pro Ala Val Glu Gly Ser Gln 
                165                 170                 175     


Val Glu Phe Leu Cys Met Ser Leu Ala Asn Pro Leu Pro Thr Asn Tyr 
            180                 185                 190         


Thr Trp Tyr His Asn Gly Lys Glu Met Gln Gly Arg Thr Glu Glu Lys 
        195                 200                 205             


Val His Ile Pro Lys Ile Leu Pro Trp His Ala Gly Thr Tyr Ser Cys 
    210                 215                 220                 


Val Ala Glu Asn Ile Leu Gly Thr Gly Gln Arg Gly Pro Gly Ala Glu 
225                 230                 235                 240 


Leu Asp Val Gln Tyr Pro Pro Lys Lys Val Thr Thr Val Ile Gln Asn 
                245                 250                 255     


Pro Met Pro Ile Arg Glu Gly Asp Thr Val Thr Leu Ser Cys Asn Tyr 
            260                 265                 270         


Asn Ser Ser Asn Pro Ser Val Thr Arg Tyr Glu Trp Lys Pro His Gly 
        275                 280                 285             


Ala Trp Glu Glu Pro Ser Leu Gly Val Leu Lys Ile Gln Asn Val Gly 
    290                 295                 300                 


Trp Asp Asn Thr Thr Ile Ala Cys Ala Ala Cys Asn Ser Trp Cys Ser 
305                 310                 315                 320 


Trp Ala Ser Pro Val Ala Leu Asn Val Gln Tyr Ala Pro Arg Asp Val 
                325                 330                 335     


Arg Val Arg Lys Ile Lys Pro Leu Ser Glu Ile His Ser Gly Asn Ser 
            340                 345                 350         


Val Ser Leu Gln Cys Asp Phe Ser Ser Ser His Pro Lys Glu Val Gln 
        355                 360                 365             


Phe Phe Trp Glu Lys Asn Gly Arg Leu Leu Gly Lys Glu Ser Gln Leu 
    370                 375                 380                 


Asn Phe Asp Ser Ile Ser Pro Glu Asp Ala Gly Ser Tyr Ser Cys Trp 
385                 390                 395                 400 


Val Asn Asn Ser Ile Gly Gln Thr Ala Ser Lys Ala Trp Thr Leu Glu 
                405                 410                 415     


Val Leu Tyr Ala Pro Arg Arg Leu Arg Val Ser Met Ser Pro Gly Asp 
            420                 425                 430         


Gln Val Met Glu Gly Lys Ser Ala Thr Leu Thr Cys Glu Ser Asp Ala 
        435                 440                 445             


Asn Pro Pro Val Ser His Tyr Thr Trp Phe Asp Trp Asn Asn Gln Ser 
    450                 455                 460                 


Leu Pro Tyr His Ser Gln Lys Leu Arg Leu Glu Pro Val Lys Val Gln 
465                 470                 475                 480 


His Ser Gly Ala Tyr Trp Cys Gln Gly Thr Asn Ser Val Gly Lys Gly 
                485                 490                 495     


Arg Ser Pro Leu Ser Thr Leu Thr Val Tyr Tyr Ser Pro Glu Thr Ile 
            500                 505                 510         


Gly Arg Arg 
        515 


<210>  163
<211>  236
<212>  PRT
<213>  Homo Sapiens

<400>  163

Glu Glu Val Leu Trp His Thr Ser Val Pro Phe Ala Glu Asn Met Ser 
1               5                   10                  15      


Leu Glu Cys Val Tyr Pro Ser Met Gly Ile Leu Thr Gln Val Glu Trp 
            20                  25                  30          


Phe Lys Ile Gly Thr Gln Gln Asp Ser Ile Ala Ile Phe Ser Pro Thr 
        35                  40                  45              


His Gly Met Val Ile Arg Lys Pro Tyr Ala Glu Arg Val Tyr Phe Leu 
    50                  55                  60                  


Asn Ser Thr Met Ala Ser Asn Asn Met Thr Leu Phe Phe Arg Asn Ala 
65                  70                  75                  80  


Ser Glu Asp Asp Val Gly Tyr Tyr Ser Cys Ser Leu Tyr Thr Tyr Pro 
                85                  90                  95      


Gln Gly Thr Trp Gln Lys Val Ile Gln Val Val Gln Ser Asp Ser Phe 
            100                 105                 110         


Glu Ala Ala Val Pro Ser Asn Ser His Ile Val Ser Glu Pro Gly Lys 
        115                 120                 125             


Asn Val Thr Leu Thr Cys Gln Pro Gln Met Thr Trp Pro Val Gln Ala 
    130                 135                 140                 


Val Arg Trp Glu Lys Ile Gln Pro Arg Gln Ile Asp Leu Leu Thr Tyr 
145                 150                 155                 160 


Cys Asn Leu Val His Gly Arg Asn Phe Thr Ser Lys Phe Pro Arg Gln 
                165                 170                 175     


Ile Val Ser Asn Cys Ser His Gly Arg Trp Ser Val Ile Val Ile Pro 
            180                 185                 190         


Asp Val Thr Val Ser Asp Ser Gly Leu Tyr Arg Cys Tyr Leu Gln Ala 
        195                 200                 205             


Ser Ala Gly Glu Asn Glu Thr Phe Val Met Arg Leu Thr Val Ala Glu 
    210                 215                 220                 


Gly Lys Thr Asp Asn Gln Tyr Thr Leu Phe Val Ala 
225                 230                 235     


<210>  164
<211>  203
<212>  PRT
<213>  Homo Sapiens

<400>  164

Cys Gln Gly Ser Ala Asp His Val Val Ser Ile Ser Gly Val Pro Leu 
1               5                   10                  15      


Gln Leu Gln Pro Asn Ser Ile Gln Thr Lys Val Asp Ser Ile Ala Trp 
            20                  25                  30          


Lys Lys Leu Leu Pro Ser Gln Asn Gly Phe His His Ile Leu Lys Trp 
        35                  40                  45              


Glu Asn Gly Ser Leu Pro Ser Asn Thr Ser Asn Asp Arg Phe Ser Phe 
    50                  55                  60                  


Ile Val Lys Asn Leu Ser Leu Leu Ile Lys Ala Ala Gln Gln Gln Asp 
65                  70                  75                  80  


Ser Gly Leu Tyr Cys Leu Glu Val Thr Ser Ile Ser Gly Lys Val Gln 
                85                  90                  95      


Thr Ala Thr Phe Gln Val Phe Val Phe Asp Lys Val Glu Lys Pro Arg 
            100                 105                 110         


Leu Gln Gly Gln Gly Lys Ile Leu Asp Arg Gly Arg Cys Gln Val Ala 
        115                 120                 125             


Leu Ser Cys Leu Val Ser Arg Asp Gly Asn Val Ser Tyr Ala Trp Tyr 
    130                 135                 140                 


Arg Gly Ser Lys Leu Ile Gln Thr Ala Gly Asn Leu Thr Tyr Leu Asp 
145                 150                 155                 160 


Glu Glu Val Asp Ile Asn Gly Thr His Thr Tyr Thr Cys Asn Val Ser 
                165                 170                 175     


Asn Pro Val Ser Trp Glu Ser His Thr Leu Asn Leu Thr Gln Asp Cys 
            180                 185                 190         


Gln Asn Ala His Gln Glu Phe Arg Phe Trp Pro 
        195                 200             


<210>  165
<211>  670
<212>  PRT
<213>  Homo Sapiens

<400>  165

Gln Asp Pro Trp Ala Ala Glu Pro Arg Ala Ala Cys Gly Pro Ser Ser 
1               5                   10                  15      


Cys Tyr Ala Leu Phe Pro Arg Arg Arg Thr Phe Leu Glu Ala Trp Arg 
            20                  25                  30          


Ala Cys Arg Glu Leu Gly Gly Asp Leu Ala Thr Pro Arg Thr Pro Glu 
        35                  40                  45              


Glu Ala Gln Arg Val Asp Ser Leu Val Gly Ala Gly Pro Ala Ser Arg 
    50                  55                  60                  


Leu Leu Trp Ile Gly Leu Gln Arg Gln Ala Arg Gln Cys Gln Leu Gln 
65                  70                  75                  80  


Arg Pro Leu Arg Gly Phe Thr Trp Thr Thr Gly Asp Gln Asp Thr Ala 
                85                  90                  95      


Phe Thr Asn Trp Ala Gln Pro Ala Ser Gly Gly Pro Cys Pro Ala Gln 
            100                 105                 110         


Arg Cys Val Ala Leu Glu Ala Ser Gly Glu His Arg Trp Leu Glu Gly 
        115                 120                 125             


Ser Cys Thr Leu Ala Val Asp Gly Tyr Leu Cys Gln Phe Gly Phe Glu 
    130                 135                 140                 


Gly Ala Cys Pro Ala Leu Gln Asp Glu Ala Gly Gln Ala Gly Pro Ala 
145                 150                 155                 160 


Val Tyr Thr Thr Pro Phe His Leu Val Ser Thr Glu Phe Glu Trp Leu 
                165                 170                 175     


Pro Phe Gly Ser Val Ala Ala Val Gln Cys Gln Ala Gly Arg Gly Ala 
            180                 185                 190         


Ser Leu Leu Cys Val Lys Gln Pro Glu Gly Gly Val Gly Trp Ser Arg 
        195                 200                 205             


Ala Gly Pro Leu Cys Leu Gly Thr Gly Cys Ser Pro Asp Asn Gly Gly 
    210                 215                 220                 


Cys Glu His Glu Cys Val Glu Glu Val Asp Gly His Val Ser Cys Arg 
225                 230                 235                 240 


Cys Thr Glu Gly Phe Arg Leu Ala Ala Asp Gly Arg Ser Cys Glu Asp 
                245                 250                 255     


Pro Cys Ala Gln Ala Pro Cys Glu Gln Gln Cys Glu Pro Gly Gly Pro 
            260                 265                 270         


Gln Gly Tyr Ser Cys His Cys Arg Leu Gly Phe Arg Pro Ala Glu Asp 
        275                 280                 285             


Asp Pro His Arg Cys Val Asp Thr Asp Glu Cys Gln Ile Ala Gly Val 
    290                 295                 300                 


Cys Gln Gln Met Cys Val Asn Tyr Val Gly Gly Phe Glu Cys Tyr Cys 
305                 310                 315                 320 


Ser Glu Gly His Glu Leu Glu Ala Asp Gly Ile Ser Cys Ser Pro Ala 
                325                 330                 335     


Gly Ala Met Gly Ala Gln Ala Ser Gln Asp Leu Gly Asp Glu Leu Leu 
            340                 345                 350         


Asp Asp Gly Glu Asp Glu Glu Asp Glu Asp Glu Ala Trp Lys Ala Phe 
        355                 360                 365             


Asn Gly Gly Trp Thr Glu Met Pro Gly Ile Leu Trp Met Glu Pro Thr 
    370                 375                 380                 


Gln Pro Pro Asp Phe Ala Leu Ala Tyr Arg Pro Ser Phe Pro Glu Asp 
385                 390                 395                 400 


Arg Glu Pro Gln Ile Pro Tyr Pro Glu Pro Thr Trp Pro Pro Pro Leu 
                405                 410                 415     


Ser Ala Pro Arg Val Pro Tyr His Ser Ser Val Leu Ser Val Thr Arg 
            420                 425                 430         


Pro Val Val Val Ser Ala Thr His Pro Thr Leu Pro Ser Ala His Gln 
        435                 440                 445             


Pro Pro Val Ile Pro Ala Thr His Pro Ala Leu Ser Arg Asp His Gln 
    450                 455                 460                 


Ile Pro Val Ile Ala Ala Asn Tyr Pro Asp Leu Pro Ser Ala Tyr Gln 
465                 470                 475                 480 


Pro Gly Ile Leu Ser Val Ser His Ser Ala Gln Pro Pro Ala His Gln 
                485                 490                 495     


Pro Pro Met Ile Ser Thr Lys Tyr Pro Glu Leu Phe Pro Ala His Gln 
            500                 505                 510         


Ser Pro Met Phe Pro Asp Thr Arg Val Ala Gly Thr Gln Thr Thr Thr 
        515                 520                 525             


His Leu Pro Gly Ile Pro Pro Asn His Ala Pro Leu Val Thr Thr Leu 
    530                 535                 540                 


Gly Ala Gln Leu Pro Pro Gln Ala Pro Asp Ala Leu Val Leu Arg Thr 
545                 550                 555                 560 


Gln Ala Thr Gln Leu Pro Ile Ile Pro Thr Ala Gln Pro Ser Leu Thr 
                565                 570                 575     


Thr Thr Ser Arg Ser Pro Val Ser Pro Ala His Gln Ile Ser Val Pro 
            580                 585                 590         


Ala Ala Thr Gln Pro Ala Ala Leu Pro Thr Leu Leu Pro Ser Gln Ser 
        595                 600                 605             


Pro Thr Asn Gln Thr Ser Pro Ile Ser Pro Thr His Pro His Ser Lys 
    610                 615                 620                 


Ala Pro Gln Ile Pro Arg Glu Asp Gly Pro Ser Pro Lys Leu Ala Leu 
625                 630                 635                 640 


Trp Leu Pro Ser Pro Ala Pro Thr Ala Ala Pro Thr Ala Leu Gly Glu 
                645                 650                 655     


Ala Gly Leu Ala Glu His Ser Gln Arg Asp Asp Arg Trp Leu 
            660                 665                 670 


<210>  166
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  166

Phe Thr Val Thr Val Pro Lys Asp Leu Tyr Val Val Glu Tyr Gly Ser 
1               5                   10                  15      


Asn Met Thr Ile Glu Cys Lys Phe Pro Val Glu Lys Gln Leu Asp Leu 
            20                  25                  30          


Ala Ala Leu Ile Val Tyr Trp Glu Met Glu Asp Lys Asn Ile Ile Gln 
        35                  40                  45              


Phe Val His Gly Glu Glu Asp Leu Lys Val Gln His Ser Ser Tyr Arg 
    50                  55                  60                  


Gln Arg Ala Arg Leu Leu Lys Asp Gln Leu Ser Leu Gly Asn Ala Ala 
65                  70                  75                  80  


Leu Gln Ile Thr Asp Val Lys Leu Gln Asp Ala Gly Val Tyr Arg Cys 
                85                  90                  95      


Met Ile Ser Tyr Gly Gly Ala Asp Tyr Lys Arg Ile Thr Val Lys Val 
            100                 105                 110         


Asn Ala Pro Tyr Asn Lys Ile Asn Gln Arg Ile Leu Val Val Asp Pro 
        115                 120                 125             


Val Thr Ser Glu His Glu Leu Thr Cys Gln Ala Glu Gly Tyr Pro Lys 
    130                 135                 140                 


Ala Glu Val Ile Trp Thr Ser Ser Asp His Gln Val Leu Ser Gly Lys 
145                 150                 155                 160 


Thr Thr Thr Thr Asn Ser Lys Arg Glu Glu Lys Leu Phe Asn Val Thr 
                165                 170                 175     


Ser Thr Leu Arg Ile Asn Thr Thr Thr Asn Glu Ile Phe Tyr Cys Thr 
            180                 185                 190         


Phe Arg Arg Leu Asp Pro Glu Glu Asn His Thr Ala Glu Leu Val Ile 
        195                 200                 205             


Pro Glu Leu Pro Leu Ala His Pro Pro Asn Glu Arg 
    210                 215                 220 


<210>  167
<211>  428
<212>  PRT
<213>  Homo Sapiens

<400>  167

Leu Glu Val Gln Val Pro Glu Asp Pro Val Val Ala Leu Val Gly Thr 
1               5                   10                  15      


Asp Ala Thr Leu Cys Cys Ser Phe Ser Pro Glu Pro Gly Phe Ser Leu 
            20                  25                  30          


Ala Gln Leu Asn Leu Ile Trp Gln Leu Thr Asp Thr Lys Gln Leu Val 
        35                  40                  45              


His Ser Phe Ala Glu Gly Gln Asp Gln Gly Ser Ala Tyr Ala Asn Arg 
    50                  55                  60                  


Thr Ala Leu Phe Pro Asp Leu Leu Ala Gln Gly Asn Ala Ser Leu Arg 
65                  70                  75                  80  


Leu Gln Arg Val Arg Val Ala Asp Glu Gly Ser Phe Thr Cys Phe Val 
                85                  90                  95      


Ser Ile Arg Asp Phe Gly Ser Ala Ala Val Ser Leu Gln Val Ala Ala 
            100                 105                 110         


Pro Tyr Ser Lys Pro Ser Met Thr Leu Glu Pro Asn Lys Asp Leu Arg 
        115                 120                 125             


Pro Gly Asp Thr Val Thr Ile Thr Cys Ser Ser Tyr Gln Gly Tyr Pro 
    130                 135                 140                 


Glu Ala Glu Val Phe Trp Gln Asp Gly Gln Gly Val Pro Leu Thr Gly 
145                 150                 155                 160 


Asn Val Thr Thr Ser Gln Met Ala Asn Glu Gln Gly Leu Phe Asp Val 
                165                 170                 175     


His Ser Ile Leu Arg Val Val Leu Gly Ala Asn Gly Thr Tyr Ser Cys 
            180                 185                 190         


Leu Val Arg Asn Pro Val Leu Gln Gln Asp Ala His Ser Ser Val Thr 
        195                 200                 205             


Ile Thr Pro Gln Arg Ser Pro Thr Gly Ala Val Glu Val Gln Val Pro 
    210                 215                 220                 


Glu Asp Pro Val Val Ala Leu Val Gly Thr Asp Ala Thr Leu Arg Cys 
225                 230                 235                 240 


Ser Phe Ser Pro Glu Pro Gly Phe Ser Leu Ala Gln Leu Asn Leu Ile 
                245                 250                 255     


Trp Gln Leu Thr Asp Thr Lys Gln Leu Val His Ser Phe Thr Glu Gly 
            260                 265                 270         


Arg Asp Gln Gly Ser Ala Tyr Ala Asn Arg Thr Ala Leu Phe Pro Asp 
        275                 280                 285             


Leu Leu Ala Gln Gly Asn Ala Ser Leu Arg Leu Gln Arg Val Arg Val 
    290                 295                 300                 


Ala Asp Glu Gly Ser Phe Thr Cys Phe Val Ser Ile Arg Asp Phe Gly 
305                 310                 315                 320 


Ser Ala Ala Val Ser Leu Gln Val Ala Ala Pro Tyr Ser Lys Pro Ser 
                325                 330                 335     


Met Thr Leu Glu Pro Asn Lys Asp Leu Arg Pro Gly Asp Thr Val Thr 
            340                 345                 350         


Ile Thr Cys Ser Ser Tyr Arg Gly Tyr Pro Glu Ala Glu Val Phe Trp 
        355                 360                 365             


Gln Asp Gly Gln Gly Val Pro Leu Thr Gly Asn Val Thr Thr Ser Gln 
    370                 375                 380                 


Met Ala Asn Glu Gln Gly Leu Phe Asp Val His Ser Val Leu Arg Val 
385                 390                 395                 400 


Val Leu Gly Ala Asn Gly Thr Tyr Ser Cys Leu Val Arg Asn Pro Val 
                405                 410                 415     


Leu Gln Gln Asp Ala His Gly Ser Val Thr Ile Thr 
            420                 425             


<210>  168
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  168

Asn Lys Ile Leu Val Lys Gln Ser Pro Met Leu Val Ala Tyr Asp Asn 
1               5                   10                  15      


Ala Val Asn Leu Ser Cys Lys Tyr Ser Tyr Asn Leu Phe Ser Arg Glu 
            20                  25                  30          


Phe Arg Ala Ser Leu His Lys Gly Leu Asp Ser Ala Val Glu Val Cys 
        35                  40                  45              


Val Val Tyr Gly Asn Tyr Ser Gln Gln Leu Gln Val Tyr Ser Lys Thr 
    50                  55                  60                  


Gly Phe Asn Cys Asp Gly Lys Leu Gly Asn Glu Ser Val Thr Phe Tyr 
65                  70                  75                  80  


Leu Gln Asn Leu Tyr Val Asn Gln Thr Asp Ile Tyr Phe Cys Lys Ile 
                85                  90                  95      


Glu Val Met Tyr Pro Pro Pro Tyr Leu Asp Asn Glu Lys Ser Asn Gly 
            100                 105                 110         


Thr Ile Ile His Val Lys Gly Lys His Leu Cys Pro Ser Pro Leu Phe 
        115                 120                 125             


Pro Gly Pro Ser Lys Pro 
    130                 


<210>  169
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  169

Leu Ser Lys Cys Arg Thr Val Ala Gly Pro Val Gly Gly Ser Leu Ser 
1               5                   10                  15      


Val Gln Cys Pro Tyr Glu Lys Glu His Arg Thr Leu Asn Lys Tyr Trp 
            20                  25                  30          


Cys Arg Pro Pro Gln Ile Phe Leu Cys Asp Lys Ile Val Glu Thr Lys 
        35                  40                  45              


Gly Ser Ala Gly Lys Arg Asn Gly Arg Val Ser Ile Arg Asp Ser Pro 
    50                  55                  60                  


Ala Asn Leu Ser Phe Thr Val Thr Leu Glu Asn Leu Thr Glu Glu Asp 
65                  70                  75                  80  


Ala Gly Thr Tyr Trp Cys Gly Val Asp Thr Pro Trp Leu Arg Asp Phe 
                85                  90                  95      


His Asp Pro Val Val Glu Val Glu Val Ser Val Phe Pro Ala Ser Thr 
            100                 105                 110         


Ser Met Thr Pro Ala Ser Ile Thr Ala Ala Lys Thr Ser Thr Ile Thr 
        115                 120                 125             


Thr Ala Phe Pro Pro Val Ser Ser Thr Thr Leu Phe Ala Val Gly Ala 
    130                 135                 140                 


Thr His Ser Ala Ser Ile Gln Glu Glu Thr Glu Glu Val Val Asn Ser 
145                 150                 155                 160 


Gln Leu Pro 
            


<210>  170
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  170

Gly Tyr Phe Pro Leu Ser His Pro Met Thr Val Ala Gly Pro Val Gly 
1               5                   10                  15      


Gly Ser Leu Ser Val Gln Cys Arg Tyr Glu Lys Glu His Arg Thr Leu 
            20                  25                  30          


Asn Lys Phe Trp Cys Arg Pro Pro Gln Ile Leu Arg Cys Asp Lys Ile 
        35                  40                  45              


Val Glu Thr Lys Gly Ser Ala Gly Lys Arg Asn Gly Arg Val Ser Ile 
    50                  55                  60                  


Arg Asp Ser Pro Ala Asn Leu Ser Phe Thr Val Thr Leu Glu Asn Leu 
65                  70                  75                  80  


Thr Glu Glu Asp Ala Gly Thr Tyr Trp Cys Gly Val Asp Thr Pro Trp 
                85                  90                  95      


Leu Arg Asp Phe His Asp Pro Ile Val Glu Val Glu Val Ser Val Phe 
            100                 105                 110         


Pro Ala Gly Thr Thr Thr Ala Ser Ser Pro Gln Ser Ser Met Gly Thr 
        115                 120                 125             


Ser Gly Pro Pro Thr Lys Leu Pro Val His Thr Trp Pro Ser Val Thr 
    130                 135                 140                 


Arg Lys Asp Ser Pro Glu Pro Ser Pro His Pro Gly Ser Leu Phe Ser 
145                 150                 155                 160 


Asn Val Arg 
            


<210>  171
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  171

Leu Lys Gly Pro Gly Ser Val Thr Gly Thr Ala Gly Asp Ser Leu Thr 
1               5                   10                  15      


Val Trp Cys Gln Tyr Glu Ser Met Tyr Lys Gly Tyr Asn Lys Tyr Trp 
            20                  25                  30          


Cys Arg Gly Gln Tyr Asp Thr Ser Cys Glu Ser Ile Val Glu Thr Lys 
        35                  40                  45              


Gly Glu Glu Lys Val Glu Arg Asn Gly Arg Val Ser Ile Arg Asp His 
    50                  55                  60                  


Pro Glu Ala Leu Ala Phe Thr Val Thr Met Gln Asn Leu Asn Glu Asp 
65                  70                  75                  80  


Asp Ala Gly Ser Tyr Trp Cys Lys Ile Gln Thr Val Trp Val Leu Asp 
                85                  90                  95      


Ser Trp Ser Arg Asp Pro Ser Asp Leu Val Arg Val Tyr Val Ser Pro 
            100                 105                 110         


Ala Ile Thr Thr Pro Arg Arg Thr Thr His Pro Ala Thr Pro Pro Ile 
        115                 120                 125             


Phe Leu Val Val Asn Pro Gly Arg Asn Leu Ser Thr Arg Glu Val Leu 
    130                 135                 140                 


Thr Gln Asn Ser Gly Phe Arg Leu Ser Ser Pro His 
145                 150                 155     


<210>  172
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  172

Ile Gln Gly Pro Glu Ser Val Arg Ala Pro Glu Gln Gly Ser Leu Thr 
1               5                   10                  15      


Val Gln Cys His Tyr Lys Gln Gly Trp Glu Thr Tyr Ile Lys Trp Trp 
            20                  25                  30          


Cys Arg Gly Val Arg Trp Asp Thr Cys Lys Ile Leu Ile Glu Thr Arg 
        35                  40                  45              


Gly Ser Glu Gln Gly Glu Lys Ser Asp Arg Val Ser Ile Lys Asp Asn 
    50                  55                  60                  


Gln Lys Asp Arg Thr Phe Thr Val Thr Met Glu Gly Leu Arg Arg Asp 
65                  70                  75                  80  


Asp Ala Asp Val Tyr Trp Cys Gly Ile Glu Arg Arg Gly Pro Asp Leu 
                85                  90                  95      


Gly Thr Gln Val Lys Val Ile Val Asp Pro Glu Gly Ala Ala Ser Thr 
            100                 105                 110         


Thr Ala Ser Ser Pro Thr Asn Ser Asn Met Ala Val Phe Ile Gly Ser 
        115                 120                 125             


His Lys Arg Asn His Tyr 
    130                 


<210>  173
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  173

Ala Lys Ile Thr Gly Pro Thr Thr Val Asn Gly Ser Glu Gln Gly Ser 
1               5                   10                  15      


Leu Thr Val Gln Cys Ala Tyr Gly Ser Gly Trp Glu Thr Tyr Leu Lys 
            20                  25                  30          


Trp Arg Cys Gln Gly Ala Asp Trp Asn Tyr Cys Asn Ile Leu Val Lys 
        35                  40                  45              


Thr Asn Gly Ser Glu Gln Glu Val Lys Lys Asn Arg Val Ser Ile Arg 
    50                  55                  60                  


Asp Asn Gln Lys Asn His Val Phe Thr Val Thr Met Glu Asn Leu Lys 
65                  70                  75                  80  


Arg Asp Asp Ala Asp Ser Tyr Trp Cys Gly Thr Glu Arg Pro Gly Ile 
                85                  90                  95      


Asp Leu Gly Val Lys Val Gln Val Thr Ile Asn Pro Gly Thr Gln Thr 
            100                 105                 110         


Ala Val Ser Glu Trp Thr Thr Thr Thr Ala Ser Leu Ala Phe Thr Ala 
        115                 120                 125             


Ala Ala Thr Gln Lys Thr Ser Ser Pro Leu Thr Arg Ser Pro Leu Lys 
    130                 135                 140                 


Ser Thr His 
145         


<210>  174
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  174

Thr Gln Ile Thr Gly Pro Thr Thr Val Asn Gly Leu Glu Arg Gly Ser 
1               5                   10                  15      


Leu Thr Val Gln Cys Val Tyr Arg Ser Gly Trp Glu Thr Tyr Leu Lys 
            20                  25                  30          


Trp Trp Cys Arg Gly Ala Ile Trp Arg Asp Cys Lys Ile Leu Val Lys 
        35                  40                  45              


Thr Ser Gly Ser Glu Gln Glu Val Lys Arg Asp Arg Val Ser Ile Lys 
    50                  55                  60                  


Asp Asn Gln Lys Asn Arg Thr Phe Thr Val Thr Met Glu Asp Leu Met 
65                  70                  75                  80  


Lys Thr Asp Ala Asp Thr Tyr Trp Cys Gly Ile Glu Lys Thr Gly Asn 
                85                  90                  95      


Asp Leu Gly Val Thr Val Gln Val Thr Ile Asp Pro Ala Pro Val Thr 
            100                 105                 110         


Gln Glu Glu Thr Ser Ser Ser Pro Thr Leu Thr Gly His His Leu Asp 
        115                 120                 125             


Asn Ser Ser Arg Asp Val Pro Arg Ala Gly Thr Ala Ala Pro Gly Gly 
    130                 135                 140                 


Arg Pro Leu Leu Cys Arg Pro Asp Pro Ala Ala Gly Arg Asn Leu Pro 
145                 150                 155                 160 


Ala Lys Gly Tyr His Glu Ala Phe Leu Cys Pro Gly 
                165                 170         


<210>  175
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  175

Leu Glu Gly Pro Glu Glu Ile Ser Gly Phe Glu Gly Asp Thr Val Ser 
1               5                   10                  15      


Leu Gln Cys Thr Tyr Arg Glu Glu Leu Arg Asp His Arg Lys Tyr Trp 
            20                  25                  30          


Cys Arg Lys Gly Gly Ile Leu Phe Ser Arg Cys Ser Gly Thr Ile Tyr 
        35                  40                  45              


Ala Glu Glu Glu Gly Gln Glu Thr Met Lys Gly Arg Val Ser Ile Arg 
    50                  55                  60                  


Asp Ser Arg Gln Glu Leu Ser Leu Ile Val Thr Leu Trp Asn Leu Thr 
65                  70                  75                  80  


Leu Gln Asp Ala Gly Glu Tyr Trp Cys Gly Val Glu Lys Arg Gly Pro 
                85                  90                  95      


Asp Glu Ser Leu Leu Ile Ser Leu Phe Val Phe Pro Gly Pro Cys Cys 
            100                 105                 110         


Pro Pro Ser Pro Ser Pro Thr Phe Gln Pro Leu Ala Thr Thr Arg Leu 
        115                 120                 125             


Gln Pro Lys Ala Lys Ala Gln Gln Thr Gln Pro Pro Gly Leu Thr Ser 
    130                 135                 140                 


Pro Gly Leu Tyr Pro Ala Ala Thr Thr Ala Lys Gln Gly Lys Thr Gly 
145                 150                 155                 160 


Ala Glu Ala Pro Pro Leu Pro Gly Thr Ser Gln Tyr Gly His Glu Arg 
                165                 170                 175     


Thr Ser Gln Tyr Thr Gly Thr Ser Pro His Pro Ala Thr Ser Pro Pro 
            180                 185                 190         


Ala Gly Ser Ser Arg Pro Pro Met Gln Leu Asn Ser Thr Ser Ala Glu 
        195                 200                 205             


Asp Thr Ser Pro Ala Leu Ser Ser Gly Ser Ser Lys Pro Arg Val Ser 
    210                 215                 220                 


Ile Pro Met Val Arg 
225                 


<210>  176
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  176

Phe Gln Asp Ser Cys Tyr Ile Phe Leu Gln Glu Ala Ile Lys Val Glu 
1               5                   10                  15      


Ser Ile Glu Asp Val Arg Asn Gln Cys Thr Asp His Gly Ala Asp Met 
            20                  25                  30          


Ile Ser Ile His Asn Glu Glu Glu Asn Ala Phe Ile Leu Asp Thr Leu 
        35                  40                  45              


Lys Lys Gln Trp Lys Gly Pro Asp Asp Ile Leu Leu Gly Met Phe Tyr 
    50                  55                  60                  


Asp Thr Asp Asp Ala Ser Phe Lys Trp Phe Asp Asn Ser Asn Met Thr 
65                  70                  75                  80  


Phe Asp Lys Trp Thr Asp Gln Asp Asp Asp Glu Asp Leu Val Asp Thr 
                85                  90                  95      


Cys Ala Phe Leu His Ile Lys Thr Gly Glu Trp Lys Lys Gly Asn Cys 
            100                 105                 110         


Glu Val Ser Ser Val Glu Gly Thr Leu Cys Lys Thr Ala Ile Pro Tyr 
        115                 120                 125             


Lys Arg Lys Tyr Leu Ser Asp Asn His 
    130                 135         


<210>  177
<211>  194
<212>  PRT
<213>  Homo Sapiens

<400>  177

Ser Pro Leu Ser Thr Pro Thr Ser Ala Gln Ala Ala Gly Pro Ser Ser 
1               5                   10                  15      


Gly Ser Cys Pro Pro Thr Lys Phe Gln Cys Arg Thr Ser Gly Leu Cys 
            20                  25                  30          


Val Pro Leu Thr Trp Arg Cys Asp Arg Asp Leu Asp Cys Ser Asp Gly 
        35                  40                  45              


Ser Asp Glu Glu Glu Cys Arg Ile Glu Pro Cys Thr Gln Lys Gly Gln 
    50                  55                  60                  


Cys Pro Pro Pro Pro Gly Leu Pro Cys Pro Cys Thr Gly Val Ser Asp 
65                  70                  75                  80  


Cys Ser Gly Gly Thr Asp Lys Lys Leu Arg Asn Cys Ser Arg Leu Ala 
                85                  90                  95      


Cys Leu Ala Gly Glu Leu Arg Cys Thr Leu Ser Asp Asp Cys Ile Pro 
            100                 105                 110         


Leu Thr Trp Arg Cys Asp Gly His Pro Asp Cys Pro Asp Ser Ser Asp 
        115                 120                 125             


Glu Leu Gly Cys Gly Thr Asn Glu Ile Leu Pro Glu Gly Asp Ala Thr 
    130                 135                 140                 


Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val Thr Ser Leu Arg Asn 
145                 150                 155                 160 


Ala Thr Thr Met Gly Pro Pro Val Thr Leu Glu Ser Val Pro Ser Val 
                165                 170                 175     


Gly Asn Ala Thr Ser Ser Ser Ala Gly Asp Gln Ser Gly Ser Pro Thr 
            180                 185                 190         


Ala Tyr 
        


<210>  178
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  178

Asp Pro Asn Phe Trp Leu Gln Val Gln Glu Ser Val Thr Val Gln Glu 
1               5                   10                  15      


Gly Leu Cys Val Leu Val Pro Cys Thr Phe Phe His Pro Ile Pro Tyr 
            20                  25                  30          


Tyr Asp Lys Asn Ser Pro Val His Gly Tyr Trp Phe Arg Glu Gly Ala 
        35                  40                  45              


Ile Ile Ser Gly Asp Ser Pro Val Ala Thr Asn Lys Leu Asp Gln Glu 
    50                  55                  60                  


Val Gln Glu Glu Thr Gln Gly Arg Phe Arg Leu Leu Gly Asp Pro Ser 
65                  70                  75                  80  


Arg Asn Asn Cys Ser Leu Ser Ile Val Asp Ala Arg Arg Arg Asp Asn 
                85                  90                  95      


Gly Ser Tyr Phe Phe Arg Met Glu Arg Gly Ser Thr Lys Tyr Ser Tyr 
            100                 105                 110         


Lys Ser Pro Gln Leu Ser Val His Val Thr Asp Leu Thr His Arg Pro 
        115                 120                 125             


Lys Ile Leu Ile Pro Gly Thr Leu Glu Pro Gly His Ser Lys Asn Leu 
    130                 135                 140                 


Thr Cys Ser Val Ser Trp Ala Cys Glu Gln Gly Thr Pro Pro Ile Phe 
145                 150                 155                 160 


Ser Trp Leu Ser Ala Ala Pro Thr Ser Leu Gly Pro Arg Thr Thr His 
                165                 170                 175     


Ser Ser Val Leu Ile Ile Thr Pro Arg Pro Gln Asp His Gly Thr Asn 
            180                 185                 190         


Leu Thr Cys Gln Val Lys Phe Ala Gly Ala Gly Val Thr Thr Glu Arg 
        195                 200                 205             


Thr Ile Gln Leu Asn Val Thr Tyr Val Pro Gln Asn Pro Thr Thr Gly 
    210                 215                 220                 


Ile Phe Pro Gly Asp Gly Ser Gly Lys Gln Glu Thr Arg Ala Gly Val 
225                 230                 235                 240 


Val His 
        


<210>  179
<211>  259
<212>  PRT
<213>  Homo Sapiens

<400>  179

Ser Leu Asp Asn Asn Gly Thr Ala Thr Pro Glu Leu Pro Thr Gln Gly 
1               5                   10                  15      


Thr Phe Ser Asn Val Ser Thr Asn Val Ser Tyr Gln Glu Thr Thr Thr 
            20                  25                  30          


Pro Ser Thr Leu Gly Ser Thr Ser Leu His Pro Val Ser Gln His Gly 
        35                  40                  45              


Asn Glu Ala Thr Thr Asn Ile Thr Glu Thr Thr Val Lys Phe Thr Ser 
    50                  55                  60                  


Thr Ser Val Ile Thr Ser Val Tyr Gly Asn Thr Asn Ser Ser Val Gln 
65                  70                  75                  80  


Ser Gln Thr Ser Val Ile Ser Thr Val Phe Thr Thr Pro Ala Asn Val 
                85                  90                  95      


Ser Thr Pro Glu Thr Thr Leu Lys Pro Ser Leu Ser Pro Gly Asn Val 
            100                 105                 110         


Ser Asp Leu Ser Thr Thr Ser Thr Ser Leu Ala Thr Ser Pro Thr Lys 
        115                 120                 125             


Pro Tyr Thr Ser Ser Ser Pro Ile Leu Ser Asp Ile Lys Ala Glu Ile 
    130                 135                 140                 


Lys Cys Ser Gly Ile Arg Glu Val Lys Leu Thr Gln Gly Ile Cys Leu 
145                 150                 155                 160 


Glu Gln Asn Lys Thr Ser Ser Cys Ala Glu Phe Lys Lys Asp Arg Gly 
                165                 170                 175     


Glu Gly Leu Ala Arg Val Leu Cys Gly Glu Glu Gln Ala Asp Ala Asp 
            180                 185                 190         


Ala Gly Ala Gln Val Cys Ser Leu Leu Leu Ala Gln Ser Glu Val Arg 
        195                 200                 205             


Pro Gln Cys Leu Leu Leu Val Leu Ala Asn Arg Thr Glu Ile Ser Ser 
    210                 215                 220                 


Lys Leu Gln Leu Met Lys Lys His Gln Ser Asp Leu Lys Lys Leu Gly 
225                 230                 235                 240 


Ile Leu Asp Phe Thr Glu Gln Asp Val Ala Ser His Gln Ser Tyr Ser 
                245                 250                 255     


Gln Lys Thr 
            


<210>  180
<211>  405
<212>  PRT
<213>  Homo Sapiens

<400>  180

Gln Lys Thr Ile Lys Lys Gln Val Val Leu Glu Glu Gly Thr Ile Ala 
1               5                   10                  15      


Phe Lys Asn Trp Val Lys Thr Gly Thr Glu Val Tyr Arg Gln Phe Trp 
            20                  25                  30          


Ile Phe Asp Val Gln Asn Pro Gln Glu Val Met Met Asn Ser Ser Asn 
        35                  40                  45              


Ile Gln Val Lys Gln Arg Gly Pro Tyr Thr Tyr Arg Val Arg Phe Leu 
    50                  55                  60                  


Ala Lys Glu Asn Val Thr Gln Asp Ala Glu Asp Asn Thr Val Ser Phe 
65                  70                  75                  80  


Leu Gln Pro Asn Gly Ala Ile Phe Glu Pro Ser Leu Ser Val Gly Thr 
                85                  90                  95      


Glu Ala Asp Asn Phe Thr Val Leu Asn Leu Ala Val Ala Ala Ala Ser 
            100                 105                 110         


His Ile Tyr Gln Asn Gln Phe Val Gln Met Ile Leu Asn Ser Leu Ile 
        115                 120                 125             


Asn Lys Ser Lys Ser Ser Met Phe Gln Val Arg Thr Leu Arg Glu Leu 
    130                 135                 140                 


Leu Trp Gly Tyr Arg Asp Pro Phe Leu Ser Leu Val Pro Tyr Pro Val 
145                 150                 155                 160 


Thr Thr Thr Val Gly Leu Phe Tyr Pro Tyr Asn Asn Thr Ala Asp Gly 
                165                 170                 175     


Val Tyr Lys Val Phe Asn Gly Lys Asp Asn Ile Ser Lys Val Ala Ile 
            180                 185                 190         


Ile Asp Thr Tyr Lys Gly Lys Arg Asn Leu Ser Tyr Trp Glu Ser His 
        195                 200                 205             


Cys Asp Met Ile Asn Gly Thr Asp Ala Ala Ser Phe Pro Pro Phe Val 
    210                 215                 220                 


Glu Lys Ser Gln Val Leu Gln Phe Phe Ser Ser Asp Ile Cys Arg Ser 
225                 230                 235                 240 


Ile Tyr Ala Val Phe Glu Ser Asp Val Asn Leu Lys Gly Ile Pro Val 
                245                 250                 255     


Tyr Arg Phe Val Leu Pro Ser Lys Ala Phe Ala Ser Pro Val Glu Asn 
            260                 265                 270         


Pro Asp Asn Tyr Cys Phe Cys Thr Glu Lys Ile Ile Ser Lys Asn Cys 
        275                 280                 285             


Thr Ser Tyr Gly Val Leu Asp Ile Ser Lys Cys Lys Glu Gly Arg Pro 
    290                 295                 300                 


Val Tyr Ile Ser Leu Pro His Phe Leu Tyr Ala Ser Pro Asp Val Ser 
305                 310                 315                 320 


Glu Pro Ile Asp Gly Leu Asn Pro Asn Glu Glu Glu His Arg Thr Tyr 
                325                 330                 335     


Leu Asp Ile Glu Pro Ile Thr Gly Phe Thr Leu Gln Phe Ala Lys Arg 
            340                 345                 350         


Leu Gln Val Asn Leu Leu Val Lys Pro Ser Glu Lys Ile Gln Val Leu 
        355                 360                 365             


Lys Asn Leu Lys Arg Asn Tyr Ile Val Pro Ile Leu Trp Leu Asn Glu 
    370                 375                 380                 


Thr Gly Thr Ile Gly Asp Glu Lys Ala Asn Met Phe Arg Ser Gln Val 
385                 390                 395                 400 


Thr Gly Lys Ile Asn 
                405 


<210>  181
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  181

Arg Ala Gln Leu Glu Arg Ser Leu Arg Asp Val Val Glu Lys Thr Ile 
1               5                   10                  15      


Gln Lys Tyr Gly Thr Asn Pro Glu Glu Thr Ala Ala Glu Glu Ser Trp 
            20                  25                  30          


Asp Tyr Val Gln Phe Gln Leu Arg Cys Cys Gly Trp His Tyr Pro Gln 
        35                  40                  45              


Asp Trp Phe Gln Val Leu Ile Leu Arg Gly Asn Gly Ser Glu Ala His 
    50                  55                  60                  


Arg Val Pro Cys Ser Cys Tyr Asn Leu Ser Ala Thr Asn Asp Ser Thr 
65                  70                  75                  80  


Ile Leu Asp Lys Val Ile Leu Pro Gln Leu Ser Arg Leu Gly His Leu 
                85                  90                  95      


Ala Arg Ser Arg His Ser Ala Asp Ile Cys Ala Val Pro Ala Glu Ser 
            100                 105                 110         


His Ile Tyr Arg Glu Gly Cys Ala Gln Gly Leu Gln Lys Trp Leu His 
        115                 120                 125             


Asn Asn 
    130 


<210>  182
<211>  258
<212>  PRT
<213>  Homo Sapiens

<400>  182

Val Pro Arg Trp Arg Gln Gln Trp Ser Gly Pro Gly Thr Thr Lys Arg 
1               5                   10                  15      


Phe Pro Glu Thr Val Leu Ala Arg Cys Val Lys Tyr Thr Glu Ile His 
            20                  25                  30          


Pro Glu Met Arg His Val Asp Cys Gln Ser Val Trp Asp Ala Phe Lys 
        35                  40                  45              


Gly Ala Phe Ile Ser Lys His Pro Cys Asn Ile Thr Glu Glu Asp Tyr 
    50                  55                  60                  


Gln Pro Leu Met Lys Leu Gly Thr Gln Thr Val Pro Cys Asn Lys Ile 
65                  70                  75                  80  


Leu Leu Trp Ser Arg Ile Lys Asp Leu Ala His Gln Phe Thr Gln Val 
                85                  90                  95      


Gln Arg Asp Met Phe Thr Leu Glu Asp Thr Leu Leu Gly Tyr Leu Ala 
            100                 105                 110         


Asp Asp Leu Thr Trp Cys Gly Glu Phe Asn Thr Ser Lys Ile Asn Tyr 
        115                 120                 125             


Gln Ser Cys Pro Asp Trp Arg Lys Asp Cys Ser Asn Asn Pro Val Ser 
    130                 135                 140                 


Val Phe Trp Lys Thr Val Ser Arg Arg Phe Ala Glu Ala Ala Cys Asp 
145                 150                 155                 160 


Val Val His Val Met Leu Asn Gly Ser Arg Ser Lys Ile Phe Asp Lys 
                165                 170                 175     


Asn Ser Thr Phe Gly Ser Val Glu Val His Asn Leu Gln Pro Glu Lys 
            180                 185                 190         


Val Gln Thr Leu Glu Ala Trp Val Ile His Gly Gly Arg Glu Asp Ser 
        195                 200                 205             


Arg Asp Leu Cys Gln Asp Pro Thr Ile Lys Glu Leu Glu Ser Ile Ile 
    210                 215                 220                 


Ser Lys Arg Asn Ile Gln Phe Ser Cys Lys Asn Ile Tyr Arg Pro Asp 
225                 230                 235                 240 


Lys Phe Leu Gln Cys Val Lys Asn Pro Glu Asp Ser Ser Cys Thr Ser 
                245                 250                 255     


Glu Ile 
        


<210>  183
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  183

Phe Lys Ile Pro Ile Glu Glu Leu Glu Asp Arg Val Phe Val Asn Cys 
1               5                   10                  15      


Asn Thr Ser Ile Thr Trp Val Glu Gly Thr Val Gly Thr Leu Leu Ser 
            20                  25                  30          


Asp Ile Thr Arg Leu Asp Leu Gly Lys Arg Ile Leu Asp Pro Arg Gly 
        35                  40                  45              


Ile Tyr Arg Cys Asn Gly Thr Asp Ile Tyr Lys Asp Lys Glu Ser Thr 
    50                  55                  60                  


Val Gln Val His Tyr Arg Met Cys Gln Ser Cys Val Glu Leu Asp Pro 
65                  70                  75                  80  


Ala Thr Val Ala 
                


<210>  184
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  184

Asp Gly Asn Glu Glu Met Gly Gly Ile Thr Gln Thr Pro Tyr Lys Val 
1               5                   10                  15      


Ser Ile Ser Gly Thr Thr Val Ile Leu Thr Cys Pro Gln Tyr Pro Gly 
            20                  25                  30          


Ser Glu Ile Leu Trp Gln His Asn Asp Lys Asn Ile Gly Gly Asp Glu 
        35                  40                  45              


Asp Asp Lys Asn Ile Gly Ser Asp Glu Asp His Leu Ser Leu Lys Glu 
    50                  55                  60                  


Phe Ser Glu Leu Glu Gln Ser Gly Tyr Tyr Val Cys Tyr Pro Arg Gly 
65                  70                  75                  80  


Ser Lys Pro Glu Asp Ala Asn Phe Tyr Leu Tyr Leu Arg Ala Arg Val 
                85                  90                  95      


Cys Glu Asn Cys Met Glu Met Asp 
            100                 


<210>  185
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  185

Gln Ser Ile Lys Gly Asn His Leu Val Lys Val Tyr Asp Tyr Gln Glu 
1               5                   10                  15      


Asp Gly Ser Val Leu Leu Thr Cys Asp Ala Glu Ala Lys Asn Ile Thr 
            20                  25                  30          


Trp Phe Lys Asp Gly Lys Met Ile Gly Phe Leu Thr Glu Asp Lys Lys 
        35                  40                  45              


Lys Trp Asn Leu Gly Ser Asn Ala Lys Asp Pro Arg Gly Met Tyr Gln 
    50                  55                  60                  


Cys Lys Gly Ser Gln Asn Lys Ser Lys Pro Leu Gln Val Tyr Tyr Arg 
65                  70                  75                  80  


Met Cys Gln Asn Cys Ile Glu Leu Asn Ala Ala Thr Ile Ser 
                85                  90                  


<210>  186
<211>  371
<212>  PRT
<213>  Homo Sapiens

<400>  186

Lys Lys Val Val Leu Gly Lys Lys Gly Asp Thr Val Glu Leu Thr Cys 
1               5                   10                  15      


Thr Ala Ser Gln Lys Lys Ser Ile Gln Phe His Trp Lys Asn Ser Asn 
            20                  25                  30          


Gln Ile Lys Ile Leu Gly Asn Gln Gly Ser Phe Leu Thr Lys Gly Pro 
        35                  40                  45              


Ser Lys Leu Asn Asp Arg Ala Asp Ser Arg Arg Ser Leu Trp Asp Gln 
    50                  55                  60                  


Gly Asn Phe Pro Leu Ile Ile Lys Asn Leu Lys Ile Glu Asp Ser Asp 
65                  70                  75                  80  


Thr Tyr Ile Cys Glu Val Glu Asp Gln Lys Glu Glu Val Gln Leu Leu 
                85                  90                  95      


Val Phe Gly Leu Thr Ala Asn Ser Asp Thr His Leu Leu Gln Gly Gln 
            100                 105                 110         


Ser Leu Thr Leu Thr Leu Glu Ser Pro Pro Gly Ser Ser Pro Ser Val 
        115                 120                 125             


Gln Cys Arg Ser Pro Arg Gly Lys Asn Ile Gln Gly Gly Lys Thr Leu 
    130                 135                 140                 


Ser Val Ser Gln Leu Glu Leu Gln Asp Ser Gly Thr Trp Thr Cys Thr 
145                 150                 155                 160 


Val Leu Gln Asn Gln Lys Lys Val Glu Phe Lys Ile Asp Ile Val Val 
                165                 170                 175     


Leu Ala Phe Gln Lys Ala Ser Ser Ile Val Tyr Lys Lys Glu Gly Glu 
            180                 185                 190         


Gln Val Glu Phe Ser Phe Pro Leu Ala Phe Thr Val Glu Lys Leu Thr 
        195                 200                 205             


Gly Ser Gly Glu Leu Trp Trp Gln Ala Glu Arg Ala Ser Ser Ser Lys 
    210                 215                 220                 


Ser Trp Ile Thr Phe Asp Leu Lys Asn Lys Glu Val Ser Val Lys Arg 
225                 230                 235                 240 


Val Thr Gln Asp Pro Lys Leu Gln Met Gly Lys Lys Leu Pro Leu His 
                245                 250                 255     


Leu Thr Leu Pro Gln Ala Leu Pro Gln Tyr Ala Gly Ser Gly Asn Leu 
            260                 265                 270         


Thr Leu Ala Leu Glu Ala Lys Thr Gly Lys Leu His Gln Glu Val Asn 
        275                 280                 285             


Leu Val Val Met Arg Ala Thr Gln Leu Gln Lys Asn Leu Thr Cys Glu 
    290                 295                 300                 


Val Trp Gly Pro Thr Ser Pro Lys Leu Met Leu Ser Leu Lys Leu Glu 
305                 310                 315                 320 


Asn Lys Glu Ala Lys Val Ser Lys Arg Glu Lys Ala Val Trp Val Leu 
                325                 330                 335     


Asn Pro Glu Ala Gly Met Trp Gln Cys Leu Leu Ser Asp Ser Gly Gln 
            340                 345                 350         


Val Leu Leu Glu Ser Asn Ile Lys Val Leu Pro Thr Trp Ser Thr Pro 
        355                 360                 365             


Val Gln Pro 
    370     


<210>  187
<211>  149
<212>  PRT
<213>  Homo Sapiens

<400>  187

Met Gln Lys Gly Asp Gln Asn Pro Gln Ile Ala Ala His Val Ile Ser 
1               5                   10                  15      


Glu Ala Ser Ser Lys Thr Thr Ser Val Leu Gln Trp Ala Glu Lys Gly 
            20                  25                  30          


Tyr Tyr Thr Met Ser Asn Asn Leu Val Thr Leu Glu Asn Gly Lys Gln 
        35                  40                  45              


Leu Thr Val Lys Arg Gln Gly Leu Tyr Tyr Ile Tyr Ala Gln Val Thr 
    50                  55                  60                  


Phe Cys Ser Asn Arg Glu Ala Ser Ser Gln Ala Pro Phe Ile Ala Ser 
65                  70                  75                  80  


Leu Cys Leu Lys Ser Pro Gly Arg Phe Glu Arg Ile Leu Leu Arg Ala 
                85                  90                  95      


Ala Asn Thr His Ser Ser Ala Lys Pro Cys Gly Gln Gln Ser Ile His 
            100                 105                 110         


Leu Gly Gly Val Phe Glu Leu Gln Pro Gly Ala Ser Val Phe Val Asn 
        115                 120                 125             


Val Thr Asp Pro Ser Gln Val Ser His Gly Thr Gly Phe Thr Ser Phe 
    130                 135                 140                 


Gly Leu Leu Lys Leu 
145                 


<210>  188
<211>  586
<212>  PRT
<213>  Homo Sapiens

<400>  188

Gln Ile Asp Leu Asn Ile Thr Cys Arg Phe Ala Gly Val Phe His Val 
1               5                   10                  15      


Glu Lys Asn Gly Arg Tyr Ser Ile Ser Arg Thr Glu Ala Ala Asp Leu 
            20                  25                  30          


Cys Lys Ala Phe Asn Ser Thr Leu Pro Thr Met Ala Gln Met Glu Lys 
        35                  40                  45              


Ala Leu Ser Ile Gly Phe Glu Thr Cys Arg Tyr Gly Phe Ile Glu Gly 
    50                  55                  60                  


His Val Val Ile Pro Arg Ile His Pro Asn Ser Ile Cys Ala Ala Asn 
65                  70                  75                  80  


Asn Thr Gly Val Tyr Ile Leu Thr Ser Asn Thr Ser Gln Tyr Asp Thr 
                85                  90                  95      


Tyr Cys Phe Asn Ala Ser Ala Pro Pro Glu Glu Asp Cys Thr Ser Val 
            100                 105                 110         


Thr Asp Leu Pro Asn Ala Phe Asp Gly Pro Ile Thr Ile Thr Ile Val 
        115                 120                 125             


Asn Arg Asp Gly Thr Arg Tyr Val Gln Lys Gly Glu Tyr Arg Thr Asn 
    130                 135                 140                 


Pro Glu Asp Ile Tyr Pro Ser Asn Pro Thr Asp Asp Asp Val Ser Ser 
145                 150                 155                 160 


Gly Ser Ser Ser Glu Arg Ser Ser Thr Ser Gly Gly Tyr Ile Phe Tyr 
                165                 170                 175     


Thr Phe Ser Thr Val His Pro Ile Pro Asp Glu Asp Ser Pro Trp Ile 
            180                 185                 190         


Thr Asp Ser Thr Asp Arg Ile Pro Ala Thr Ser Thr Ser Ser Asn Thr 
        195                 200                 205             


Ile Ser Ala Gly Trp Glu Pro Asn Glu Glu Asn Glu Asp Glu Arg Asp 
    210                 215                 220                 


Arg His Leu Ser Phe Ser Gly Ser Gly Ile Asp Asp Asp Glu Asp Phe 
225                 230                 235                 240 


Ile Ser Ser Thr Ile Ser Thr Thr Pro Arg Ala Phe Asp His Thr Lys 
                245                 250                 255     


Gln Asn Gln Asp Trp Thr Gln Trp Asn Pro Ser His Ser Asn Pro Glu 
            260                 265                 270         


Val Leu Leu Gln Thr Thr Thr Arg Met Thr Asp Val Asp Arg Asn Gly 
        275                 280                 285             


Thr Thr Ala Tyr Glu Gly Asn Trp Asn Pro Glu Ala His Pro Pro Leu 
    290                 295                 300                 


Ile His His Glu His His Glu Glu Glu Glu Thr Pro His Ser Thr Ser 
305                 310                 315                 320 


Thr Ile Gln Ala Thr Pro Ser Ser Thr Thr Glu Glu Thr Ala Thr Gln 
                325                 330                 335     


Lys Glu Gln Trp Phe Gly Asn Arg Trp His Glu Gly Tyr Arg Gln Thr 
            340                 345                 350         


Pro Arg Glu Asp Ser His Ser Thr Thr Gly Thr Ala Ala Ala Ser Ala 
        355                 360                 365             


His Thr Ser His Pro Met Gln Gly Arg Thr Thr Pro Ser Pro Glu Asp 
    370                 375                 380                 


Ser Ser Trp Thr Asp Phe Phe Asn Pro Ile Ser His Pro Met Gly Arg 
385                 390                 395                 400 


Gly His Gln Ala Gly Arg Arg Met Asp Met Asp Ser Ser His Ser Thr 
                405                 410                 415     


Thr Leu Gln Pro Thr Ala Asn Pro Asn Thr Gly Leu Val Glu Asp Leu 
            420                 425                 430         


Asp Arg Thr Gly Pro Leu Ser Met Thr Thr Gln Gln Ser Asn Ser Gln 
        435                 440                 445             


Ser Phe Ser Thr Ser His Glu Gly Leu Glu Glu Asp Lys Asp His Pro 
    450                 455                 460                 


Thr Thr Ser Thr Leu Thr Ser Ser Asn Arg Asn Asp Val Thr Gly Gly 
465                 470                 475                 480 


Arg Arg Asp Pro Asn His Ser Glu Gly Ser Thr Thr Leu Leu Glu Gly 
                485                 490                 495     


Tyr Thr Ser His Tyr Pro His Thr Lys Glu Ser Arg Thr Phe Ile Pro 
            500                 505                 510         


Val Thr Ser Ala Lys Thr Gly Ser Phe Gly Val Thr Ala Val Thr Val 
        515                 520                 525             


Gly Asp Ser Asn Ser Asn Val Asn Arg Ser Leu Ser Gly Asp Gln Asp 
    530                 535                 540                 


Thr Phe His Pro Ser Gly Gly Ser His Thr Thr His Gly Ser Glu Ser 
545                 550                 555                 560 


Asp Gly His Ser His Gly Ser Gln Glu Gly Gly Ala Asn Thr Thr Ser 
                565                 570                 575     


Gly Pro Ile Arg Thr Pro Gln Ile Pro Glu 
            580                 585     


<210>  189
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  189

Gln Leu Leu Phe Asn Lys Thr Lys Ser Val Glu Phe Thr Phe Cys Asn 
1               5                   10                  15      


Asp Thr Val Val Ile Pro Cys Phe Val Thr Asn Met Glu Ala Gln Asn 
            20                  25                  30          


Thr Thr Glu Val Tyr Val Lys Trp Lys Phe Lys Gly Arg Asp Ile Tyr 
        35                  40                  45              


Thr Phe Asp Gly Ala Leu Asn Lys Ser Thr Val Pro Thr Asp Phe Ser 
    50                  55                  60                  


Ser Ala Lys Ile Glu Val Ser Gln Leu Leu Lys Gly Asp Ala Ser Leu 
65                  70                  75                  80  


Lys Met Asp Lys Ser Asp Ala Val Ser His Thr Gly Asn Tyr Thr Cys 
                85                  90                  95      


Glu Val Thr Glu Leu Thr Arg Glu Gly Glu Thr Ile Ile Glu Leu Lys 
            100                 105                 110         


Tyr Arg Val Val Ser Trp Phe Ser Pro Asn Glu 
        115                 120             


<210>  190
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  190

Met Cys Ser Arg Gly Trp Asp Ser Cys Leu Ala Leu Glu Leu Leu Leu 
1               5                   10                  15      


Leu Pro Leu Ser Leu Leu Val Thr Ser Ile Gln Gly His Leu Val His 
            20                  25                  30          


Met Thr Val Val Ser Gly Ser Asn Val Thr Leu Asn Ile Ser Glu Ser 
        35                  40                  45              


Leu Pro Glu Asn Tyr Lys Gln Leu Thr Trp Phe Tyr Thr Phe Asp Gln 
    50                  55                  60                  


Lys Ile Val Glu Trp Asp Ser Arg Lys Ser Lys Tyr Phe Glu Ser Lys 
65                  70                  75                  80  


Phe Lys Gly Arg Val Arg Leu Asp Pro Gln Ser Gly Ala Leu Tyr Ile 
                85                  90                  95      


Ser Lys Val Gln Lys Glu Asp Asn Ser Thr Tyr Ile Met Arg Val Leu 
            100                 105                 110         


Lys Lys Thr Gly Asn Glu Gln Glu Trp Lys Ile Lys Leu Gln Val Leu 
        115                 120                 125             


Gly Glu Ser Gly Glu Pro Lys Ser Lys Ser Pro Leu Gln Trp Pro Gln 
    130                 135                 140                 


Met Asp His Cys Arg Ala Ser Trp Glu Ala Trp Gly Thr Leu Gly Glu 
145                 150                 155                 160 


Glu Glu Arg Lys Thr Ser Gly Gln Val 
                165                 


<210>  191
<211>  348
<212>  PRT
<213>  Homo Sapiens

<400>  191

Arg Leu Ser Trp Tyr Asp Pro Asp Phe Gln Ala Arg Leu Thr Arg Ser 
1               5                   10                  15      


Asn Ser Lys Cys Gln Gly Gln Leu Glu Val Tyr Leu Lys Asp Gly Trp 
            20                  25                  30          


His Met Val Cys Ser Gln Ser Trp Gly Arg Ser Ser Lys Gln Trp Glu 
        35                  40                  45              


Asp Pro Ser Gln Ala Ser Lys Val Cys Gln Arg Leu Asn Cys Gly Val 
    50                  55                  60                  


Pro Leu Ser Leu Gly Pro Phe Leu Val Thr Tyr Thr Pro Gln Ser Ser 
65                  70                  75                  80  


Ile Ile Cys Tyr Gly Gln Leu Gly Ser Phe Ser Asn Cys Ser His Ser 
                85                  90                  95      


Arg Asn Asp Met Cys His Ser Leu Gly Leu Thr Cys Leu Glu Pro Gln 
            100                 105                 110         


Lys Thr Thr Pro Pro Thr Thr Arg Pro Pro Pro Thr Thr Thr Pro Glu 
        115                 120                 125             


Pro Thr Ala Pro Pro Arg Leu Gln Leu Val Ala Gln Ser Gly Gly Gln 
    130                 135                 140                 


His Cys Ala Gly Val Val Glu Phe Tyr Ser Gly Ser Leu Gly Gly Thr 
145                 150                 155                 160 


Ile Ser Tyr Glu Ala Gln Asp Lys Thr Gln Asp Leu Glu Asn Phe Leu 
                165                 170                 175     


Cys Asn Asn Leu Gln Cys Gly Ser Phe Leu Lys His Leu Pro Glu Thr 
            180                 185                 190         


Glu Ala Gly Arg Ala Gln Asp Pro Gly Glu Pro Arg Glu His Gln Pro 
        195                 200                 205             


Leu Pro Ile Gln Trp Lys Ile Gln Asn Ser Ser Cys Thr Ser Leu Glu 
    210                 215                 220                 


His Cys Phe Arg Lys Ile Lys Pro Gln Lys Ser Gly Arg Val Leu Ala 
225                 230                 235                 240 


Leu Leu Cys Ser Gly Phe Gln Pro Lys Val Gln Ser Arg Leu Val Gly 
                245                 250                 255     


Gly Ser Ser Ile Cys Glu Gly Thr Val Glu Val Arg Gln Gly Ala Gln 
            260                 265                 270         


Trp Ala Ala Leu Cys Asp Ser Ser Ser Ala Arg Ser Ser Leu Arg Trp 
        275                 280                 285             


Glu Glu Val Cys Arg Glu Gln Gln Cys Gly Ser Val Asn Ser Tyr Arg 
    290                 295                 300                 


Val Leu Asp Ala Gly Asp Pro Thr Ser Arg Gly Leu Phe Cys Pro His 
305                 310                 315                 320 


Gln Lys Leu Ser Gln Cys His Glu Leu Trp Glu Arg Asn Ser Tyr Cys 
                325                 330                 335     


Lys Lys Val Phe Val Thr Cys Gln Asp Pro Asn Pro 
            340                 345             


<210>  192
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  192

Glu Gln Lys Leu Asn Glu Tyr Val Ala Lys Gly Leu Thr Asp Ser Ile 
1               5                   10                  15      


His Arg Tyr His Ser Asp Asn Ser Thr Lys Ala Ala Trp Asp Ser Ile 
            20                  25                  30          


Gln Ser Phe Leu Gln Cys Cys Gly Ile Asn Gly Thr Ser Asp Trp Thr 
        35                  40                  45              


Ser Gly Pro Pro Ala Ser Cys Pro Ser Asp Arg Lys Val Glu Gly Cys 
    50                  55                  60                  


Tyr Ala Lys Ala Arg Leu Trp Phe His Ser Asn 
65                  70                  75  


<210>  193
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  193

Asp Cys Gly Leu Pro Pro Asp Val Pro Asn Ala Gln Pro Ala Leu Glu 
1               5                   10                  15      


Gly Arg Thr Ser Phe Pro Glu Asp Thr Val Ile Thr Tyr Lys Cys Glu 
            20                  25                  30          


Glu Ser Phe Val Lys Ile Pro Gly Glu Lys Asp Ser Val Ile Cys Leu 
        35                  40                  45              


Lys Gly Ser Gln Trp Ser Asp Ile Glu Glu Phe Cys Asn Arg Ser Cys 
    50                  55                  60                  


Glu Val Pro Thr Arg Leu Asn Ser Ala Ser Leu Lys Gln Pro Tyr Ile 
65                  70                  75                  80  


Thr Gln Asn Tyr Phe Pro Val Gly Thr Val Val Glu Tyr Glu Cys Arg 
                85                  90                  95      


Pro Gly Tyr Arg Arg Glu Pro Ser Leu Ser Pro Lys Leu Thr Cys Leu 
            100                 105                 110         


Gln Asn Leu Lys Trp Ser Thr Ala Val Glu Phe Cys Lys Lys Lys Ser 
        115                 120                 125             


Cys Pro Asn Pro Gly Glu Ile Arg Asn Gly Gln Ile Asp Val Pro Gly 
    130                 135                 140                 


Gly Ile Leu Phe Gly Ala Thr Ile Ser Phe Ser Cys Asn Thr Gly Tyr 
145                 150                 155                 160 


Lys Leu Phe Gly Ser Thr Ser Ser Phe Cys Leu Ile Ser Gly Ser Ser 
                165                 170                 175     


Val Gln Trp Ser Asp Pro Leu Pro Glu Cys Arg Glu Ile Tyr Cys Pro 
            180                 185                 190         


Ala Pro Pro Gln Ile Asp Asn Gly Ile Ile Gln Gly Glu Arg Asp His 
        195                 200                 205             


Tyr Gly Tyr Arg Gln Ser Val Thr Tyr Ala Cys Asn Lys Gly Phe Thr 
    210                 215                 220                 


Met Ile Gly Glu His Ser Ile Tyr Cys Thr Val Asn Asn Asp Glu Gly 
225                 230                 235                 240 


Glu Trp Ser Gly Pro Pro Pro Glu Cys Arg Gly Lys Ser Leu Thr Ser 
                245                 250                 255     


Lys Val Pro Pro Thr Val Gln Lys Pro Thr Thr Val Asn Val Pro Thr 
            260                 265                 270         


Thr Glu Val Ser Pro Thr Ser Gln Lys Thr Thr Thr Lys Thr Thr Thr 
        275                 280                 285             


Pro Asn Ala Gln Ala Thr Arg Ser Thr Pro Val Ser Arg Thr Thr Lys 
    290                 295                 300                 


His Phe His Glu Thr Thr Pro Asn Lys Gly Ser Gly Thr Thr Ser 
305                 310                 315                 


<210>  194
<211>  187
<212>  PRT
<213>  Homo Sapiens

<400>  194

Phe Ser Gln Gln Ile Tyr Gly Val Val Tyr Gly Asn Val Thr Phe His 
1               5                   10                  15      


Val Pro Ser Asn Val Pro Leu Lys Glu Val Leu Trp Lys Lys Gln Lys 
            20                  25                  30          


Asp Lys Val Ala Glu Leu Glu Asn Ser Glu Phe Arg Ala Phe Ser Ser 
        35                  40                  45              


Phe Lys Asn Arg Val Tyr Leu Asp Thr Val Ser Gly Ser Leu Thr Ile 
    50                  55                  60                  


Tyr Asn Leu Thr Ser Ser Asp Glu Asp Glu Tyr Glu Met Glu Ser Pro 
65                  70                  75                  80  


Asn Ile Thr Asp Thr Met Lys Phe Phe Leu Tyr Val Leu Glu Ser Leu 
                85                  90                  95      


Pro Ser Pro Thr Leu Thr Cys Ala Leu Thr Asn Gly Ser Ile Glu Val 
            100                 105                 110         


Gln Cys Met Ile Pro Glu His Tyr Asn Ser His Arg Gly Leu Ile Met 
        115                 120                 125             


Tyr Ser Trp Asp Cys Pro Met Glu Gln Cys Lys Arg Asn Ser Thr Ser 
    130                 135                 140                 


Ile Tyr Phe Lys Met Glu Asn Asp Leu Pro Gln Lys Ile Gln Cys Thr 
145                 150                 155                 160 


Leu Ser Asn Pro Leu Phe Asn Thr Thr Ser Ser Ile Ile Leu Thr Thr 
                165                 170                 175     


Cys Ile Pro Ser Ser Gly His Ser Arg His Arg 
            180                 185         


<210>  195
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  195

Leu Gln Cys Tyr Asn Cys Pro Asn Pro Thr Ala Asp Cys Lys Thr Ala 
1               5                   10                  15      


Val Asn Cys Ser Ser Asp Phe Asp Ala Cys Leu Ile Thr Lys Ala Gly 
            20                  25                  30          


Leu Gln Val Tyr Asn Lys Cys Trp Lys Phe Glu His Cys Asn Phe Asn 
        35                  40                  45              


Asp Val Thr Thr Arg Leu Arg Glu Asn Glu Leu Thr Tyr Tyr Cys Cys 
    50                  55                  60                  


Lys Lys Asp Leu Cys Asn Phe Asn Glu Gln Leu Glu Asn 
65                  70                  75          


<210>  196
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  196

His Pro Ser Pro Ala Pro Pro Asp Gln Leu Asn Thr Ser Ser Ala Glu 
1               5                   10                  15      


Ser Glu Leu Trp Glu Pro Gly Glu Arg Leu Pro Val Arg Leu Thr Asn 
            20                  25                  30          


Gly Ser Ser Ser Cys Ser Gly Thr Val Glu Val Arg Leu Glu Ala Ser 
        35                  40                  45              


Trp Glu Pro Ala Cys Gly Ala Leu Trp Asp Ser Arg Ala Ala Glu Ala 
    50                  55                  60                  


Val Cys Arg Ala Leu Gly Cys Gly Gly Ala Glu Ala Ala Ser Gln Leu 
65                  70                  75                  80  


Ala Pro Pro Thr Pro Glu Leu Pro Pro Pro Pro Ala Ala Gly Asn Thr 
                85                  90                  95      


Ser Val Ala Ala Asn Ala Thr Leu Ala Gly Ala Pro Ala Leu Leu Cys 
            100                 105                 110         


Ser Gly Ala Glu Trp Arg Leu Cys Glu Val Val Glu His Ala Cys Arg 
        115                 120                 125             


Ser Asp Gly Arg Arg Ala Arg Val Thr Cys Ala Glu Asn Arg Ala Leu 
    130                 135                 140                 


Arg Leu Val Asp Gly Gly Gly Ala Cys Ala Gly Arg Val Glu Met Leu 
145                 150                 155                 160 


Glu His Gly Glu Trp Gly Ser Val Cys Asp Asp Thr Trp Asp Leu Glu 
                165                 170                 175     


Asp Ala His Val Val Cys Arg Gln Leu Gly Cys Gly Trp Ala Val Gln 
            180                 185                 190         


Ala Leu Pro Gly Leu His Phe Met Pro Gly Arg Gly Pro Ile His Arg 
        195                 200                 205             


Asp Gln Val Asn Cys Ser Gly Ala Glu Ala Tyr Leu Trp Asp Cys Pro 
    210                 215                 220                 


Gly Leu Pro Gly Gln His Tyr Cys Gly His Lys Glu Asp Ala Gly Val 
225                 230                 235                 240 


Val Cys Ser Glu His Gln Ser Trp Arg Leu Thr Gly Gly Ala Asp Arg 
                245                 250                 255     


Cys Glu Gly Gln Val Glu Val His Phe Arg Gly Val Trp Asn Thr Val 
            260                 265                 270         


Cys Asp Ser Glu Trp Tyr Pro Ser Glu Ala Lys Val Leu Cys Gln Ser 
        275                 280                 285             


Leu Gly Cys Gly Thr Ala Val Glu Arg Pro Lys Gly Leu Pro His Ser 
    290                 295                 300                 


Leu Ser Gly Arg Met Tyr Tyr Ser Cys Asn Gly Glu Glu Leu Thr Leu 
305                 310                 315                 320 


Ser Asn Cys Ser Trp Arg Phe Asn Asn Ser Asn Leu Cys Ser Gln Ser 
                325                 330                 335     


Leu Ala Ala Arg Val Leu Cys Ser Ala Ser Arg Ser Leu His Asn Leu 
            340                 345                 350         


Ser Thr Pro Glu Val Pro Ala Ser Val Gln Thr Val Thr Ile Glu Ser 
        355                 360                 365             


Ser Val Thr Val Lys Ile Glu Asn Lys Glu Ser Arg Glu Leu Met Leu 
    370                 375                 380                 


Leu 
385 


<210>  197
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  197

Ala Gly Tyr Val Phe Arg Asp Lys Val Met Ser Glu Phe Asn Asn Asn 
1               5                   10                  15      


Phe Arg Gln Gln Met Glu Asn Tyr Pro Lys Asn Asn His Thr Ala Ser 
            20                  25                  30          


Ile Leu Asp Arg Met Gln Ala Asp Phe Lys Cys Cys Gly Ala Ala Asn 
        35                  40                  45              


Tyr Thr Asp Trp Glu Lys Ile Pro Ser Met Ser Lys Asn Arg Val Pro 
    50                  55                  60                  


Asp Ser Cys Cys Ile Asn Val Thr Val Gly Cys Gly Ile Asn Phe Asn 
65                  70                  75                  80  


Glu Lys Ala Ile His Lys Glu Gly Cys Val Glu Lys Ile Gly Gly Trp 
                85                  90                  95      


Leu Arg Lys Asn Val 
            100     


<210>  198
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  198

Ser Val Gly Gln Tyr Asn Cys Pro Gly Gln Tyr Thr Phe Ser Met Pro 
1               5                   10                  15      


Ser Asp Ser His Val Ser Ser Cys Ser Glu Asp Trp Val Gly Tyr Gln 
            20                  25                  30          


Arg Lys Cys Tyr Phe Ile Ser Thr Val Lys Arg Ser Trp Thr Ser Ala 
        35                  40                  45              


Gln Asn Ala Cys Ser Glu His Gly Ala Thr Leu Ala Val Ile Asp Ser 
    50                  55                  60                  


Glu Lys Asp Met Asn Phe Leu Lys Arg Tyr Ala Gly Arg Glu Glu His 
65                  70                  75                  80  


Trp Val Gly Leu Lys Lys Glu Pro Gly His Pro Trp Lys Trp Ser Asn 
                85                  90                  95      


Gly Lys Glu Phe Asn Asn Trp Phe Asn Val Thr Gly Ser Asp Lys Cys 
            100                 105                 110         


Val Phe Leu Lys Asn Thr Glu Val Ser Ser Met Glu Cys Glu Lys Asn 
        115                 120                 125             


Leu Tyr Trp Ile Cys Asn Lys Pro Tyr Lys 
    130                 135             


<210>  199
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  199

Ala Gln Glu Val Gln Gln Ser Pro His Cys Thr Thr Val Pro Val Gly 
1               5                   10                  15      


Ala Ser Val Asn Ile Thr Cys Ser Thr Ser Gly Gly Leu Arg Gly Ile 
            20                  25                  30          


Tyr Leu Arg Gln Leu Gly Pro Gln Pro Gln Asp Ile Ile Tyr Tyr Glu 
        35                  40                  45              


Asp Gly Val Val Pro Thr Thr Asp Arg Arg Phe Arg Gly Arg Ile Asp 
    50                  55                  60                  


Phe Ser Gly Ser Gln Asp Asn Leu Thr Ile Thr Met His Arg Leu Gln 
65                  70                  75                  80  


Leu Ser Asp Thr Gly Thr Tyr Thr Cys Gln Ala Ile Thr Glu Val Asn 
                85                  90                  95      


Val Tyr Gly Ser Gly Thr Leu Val Leu Val Thr Glu Glu Gln Ser Gln 
            100                 105                 110         


Gly Trp His Arg Cys Ser Asp Ala Pro Pro Arg Ala Ser Ala Leu Pro 
        115                 120                 125             


Ala Pro Pro Thr Gly Ser Ala Leu Pro Asp Pro Gln Thr Ala Ser Ala 
    130                 135                 140                 


Leu Pro Asp Pro Pro Ala Ala Ser Ala Leu Pro 
145                 150                 155 


<210>  200
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  200

Gln Arg Phe Ala Gln Ala Gln Gln Gln Leu Pro Leu Glu Ser Leu Gly 
1               5                   10                  15      


Trp Asp Val Ala Glu Leu Gln Leu Asn His Thr Gly Pro Gln Gln Asp 
            20                  25                  30          


Pro Arg Leu Tyr Trp Gln Gly Gly Pro Ala Leu Gly Arg Ser Phe Leu 
        35                  40                  45              


His Gly Pro Glu Leu Asp Lys Gly Gln Leu Arg Ile His Arg Asp Gly 
    50                  55                  60                  


Ile Tyr Met Val His Ile Gln Val Thr Leu Ala Ile Cys Ser Ser Thr 
65                  70                  75                  80  


Thr Ala Ser Arg His His Pro Thr Thr Leu Ala Val Gly Ile Cys Ser 
                85                  90                  95      


Pro Ala Ser Arg Ser Ile Ser Leu Leu Arg Leu Ser Phe His Gln Gly 
            100                 105                 110         


Cys Thr Ile Ala Ser Gln Arg Leu Thr Pro Leu Ala Arg Gly Asp Thr 
        115                 120                 125             


Leu Cys Thr Asn Leu Thr Gly Thr Leu Leu Pro Ser Arg Asn Thr Asp 
    130                 135                 140                 


Glu Thr Phe Phe Gly Val Gln Trp Val Arg Pro 
145                 150                 155 


<210>  201
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  201

Arg Tyr Leu Gln Val Ser Gln Gln Leu Gln Gln Thr Asn Arg Val Leu 
1               5                   10                  15      


Glu Val Thr Asn Ser Ser Leu Arg Gln Gln Leu Arg Leu Lys Ile Thr 
            20                  25                  30          


Gln Leu Gly Gln Ser Ala Glu Asp Leu Gln Gly Ser Arg Arg Glu Leu 
        35                  40                  45              


Ala Gln Ser Gln Glu Ala Leu Gln Val Glu Gln Arg Ala His Gln Ala 
    50                  55                  60                  


Ala Glu Gly Gln Leu Gln Ala Cys Gln Ala Asp Arg Gln Lys Thr Lys 
65                  70                  75                  80  


Glu Thr Leu Gln Ser Glu Glu Gln Gln Arg Arg Ala Leu Glu Gln Lys 
                85                  90                  95      


Leu Ser Asn Met Glu Asn Arg Leu Lys Pro Phe Phe Thr Cys Gly Ser 
            100                 105                 110         


Ala Asp Thr Cys Cys Pro Ser Gly Trp Ile Met His Gln Lys Ser Cys 
        115                 120                 125             


Phe Tyr Ile Ser Leu Thr Ser Lys Asn Trp Gln Glu Ser Gln Lys Gln 
    130                 135                 140                 


Cys Glu Thr Leu Ser Ser Lys Leu Ala Thr Phe Ser Glu Ile Tyr Pro 
145                 150                 155                 160 


Gln Ser His Ser Tyr Tyr Phe Leu Asn Ser Leu Leu Pro Asn Gly Gly 
                165                 170                 175     


Ser Gly Asn Ser Tyr Trp Thr Gly Leu Ser Ser Asn Lys Asp Trp Lys 
            180                 185                 190         


Leu Thr Asp Asp Thr Gln Arg Thr Arg Thr Tyr Ala Gln Ser Ser Lys 
        195                 200                 205             


Cys Asn Lys Val His Lys Thr Trp Ser Trp Trp Thr Leu Glu Ser Glu 
    210                 215                 220                 


Ser Cys Arg Ser Ser Leu Pro Tyr Ile Cys Glu Met Thr Ala Phe Arg 
225                 230                 235                 240 


Phe Pro Asp 
            


<210>  202
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  202

Gln Gln Gln Gly Arg Leu Asp Lys Leu Thr Val Thr Ser Gln Asn Leu 
1               5                   10                  15      


Gln Leu Glu Asn Leu Arg Met Lys Leu Pro Lys Pro Pro Lys Pro Val 
            20                  25                  30          


Ser Lys Met Arg Met Ala Thr Pro Leu Leu Met Gln Ala Leu Pro Met 
        35                  40                  45              


Gly Ala Leu Pro Gln Gly Pro Met Gln Asn Ala Thr Lys Tyr Gly Asn 
    50                  55                  60                  


Met Thr Glu Asp His Val Met His Leu Leu Gln Asn Ala Asp Pro Leu 
65                  70                  75                  80  


Lys Val Tyr Pro Pro Leu Lys Gly Ser Phe Pro Glu Asn Leu Arg His 
                85                  90                  95      


Leu Lys Asn Thr Met Glu Thr Ile Asp Trp Lys Val Phe Glu Ser Trp 
            100                 105                 110         


Met His His Trp Leu Leu Phe Glu Met Ser Arg His Ser Leu Glu Gln 
        115                 120                 125             


Lys Pro Thr Asp Ala Pro Pro Lys Glu Ser Leu Glu Leu Glu Asp Pro 
    130                 135                 140                 


Ser Ser Gly Leu Gly Val Thr Lys Gln Asp Leu Gly Pro Val Pro Met 
145                 150                 155                 160 


<210>  203
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  203

Leu Trp Met His Lys Val Pro Ala Ser Leu Met Val Ser Leu Gly Glu 
1               5                   10                  15      


Asp Ala His Phe Gln Cys Pro His Asn Ser Ser Asn Asn Ala Asn Val 
            20                  25                  30          


Thr Trp Trp Arg Val Leu His Gly Asn Tyr Thr Trp Pro Pro Glu Phe 
        35                  40                  45              


Leu Gly Pro Gly Glu Asp Pro Asn Gly Thr Leu Ile Ile Gln Asn Val 
    50                  55                  60                  


Asn Lys Ser His Gly Gly Ile Tyr Val Cys Arg Val Gln Glu Gly Asn 
65                  70                  75                  80  


Glu Ser Tyr Gln Gln Ser Cys Gly Thr Tyr Leu Arg Val Arg Gln Pro 
                85                  90                  95      


Pro Pro Arg Pro Phe Leu Asp Met Gly Glu Gly Thr Lys Asn Arg 
            100                 105                 110     


<210>  204
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  204

Ala Arg Ser Glu Asp Arg Tyr Arg Asn Pro Lys Gly Ser Ala Cys Ser 
1               5                   10                  15      


Arg Ile Trp Gln Ser Pro Arg Phe Ile Ala Arg Lys Arg Gly Phe Thr 
            20                  25                  30          


Val Lys Met His Cys Tyr Met Asn Ser Ala Ser Gly Asn Val Ser Trp 
        35                  40                  45              


Leu Trp Lys Gln Glu Met Asp Glu Asn Pro Gln Gln Leu Lys Leu Glu 
    50                  55                  60                  


Lys Gly Arg Met Glu Glu Ser Gln Asn Glu Ser Leu Ala Thr Leu Thr 
65                  70                  75                  80  


Ile Gln Gly Ile Arg Phe Glu Asp Asn Gly Ile Tyr Phe Cys Gln Gln 
                85                  90                  95      


Lys Cys Asn Asn Thr Ser Glu Val Tyr Gln Gly Cys Gly Thr Glu Leu 
            100                 105                 110         


Arg Val Met Gly Phe Ser Thr Leu Ala Gln Leu Lys Gln Arg Asn Thr 
        115                 120                 125             


Leu Lys Asp 
    130     


<210>  205
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  205

Val Ile His Val Thr Lys Glu Val Lys Glu Val Ala Thr Leu Ser Cys 
1               5                   10                  15      


Gly His Asn Val Ser Val Glu Glu Leu Ala Gln Thr Arg Ile Tyr Trp 
            20                  25                  30          


Gln Lys Glu Lys Lys Met Val Leu Thr Met Met Ser Gly Asp Met Asn 
        35                  40                  45              


Ile Trp Pro Glu Tyr Lys Asn Arg Thr Ile Phe Asp Ile Thr Asn Asn 
    50                  55                  60                  


Leu Ser Ile Val Ile Leu Ala Leu Arg Pro Ser Asp Glu Gly Thr Tyr 
65                  70                  75                  80  


Glu Cys Val Val Leu Lys Tyr Glu Lys Asp Ala Phe Lys Arg Glu His 
                85                  90                  95      


Leu Ala Glu Val Thr Leu Ser Val Lys Ala Asp Phe Pro Thr Pro Ser 
            100                 105                 110         


Ile Ser Asp Phe Glu Ile Pro Thr Ser Asn Ile Arg Arg Ile Ile Cys 
        115                 120                 125             


Ser Thr Ser Gly Gly Phe Pro Glu Pro His Leu Ser Trp Leu Glu Asn 
    130                 135                 140                 


Gly Glu Glu Leu Asn Ala Ile Asn Thr Thr Val Ser Gln Asp Pro Glu 
145                 150                 155                 160 


Thr Glu Leu Tyr Ala Val Ser Ser Lys Leu Asp Phe Asn Met Thr Thr 
                165                 170                 175     


Asn His Ser Phe Met Cys Leu Ile Lys Tyr Gly His Leu Arg Val Asn 
            180                 185                 190         


Gln Thr Phe Asn Trp Asn Thr Thr Lys Gln Glu His Phe Pro Asp Asn 
        195                 200                 205             


<210>  206
<211>  89
<212>  PRT
<213>  Homo Sapiens

<400>  206

Phe Val Asn Lys Asp Gln Ile Ala Lys Asp Val Lys Gln Phe Tyr Asp 
1               5                   10                  15      


Gln Ala Leu Gln Gln Ala Val Val Asp Asp Asp Ala Asn Asn Ala Lys 
            20                  25                  30          


Ala Val Val Lys Thr Phe His Glu Thr Leu Asp Cys Cys Gly Ser Ser 
        35                  40                  45              


Thr Leu Thr Ala Leu Thr Thr Ser Val Leu Lys Asn Asn Leu Cys Pro 
    50                  55                  60                  


Ser Gly Ser Asn Ile Ile Ser Asn Leu Phe Lys Glu Asp Cys His Gln 
65                  70                  75                  80  


Lys Ile Asp Asp Leu Phe Ser Gly Lys 
                85                  


<210>  207
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  207

Gly Lys Leu Lys Gln Glu Met Gly Gly Ile Val Thr Glu Leu Ile Arg 
1               5                   10                  15      


Asp Tyr Asn Ser Ser Arg Glu Asp Ser Leu Gln Asp Ala Trp Asp Tyr 
            20                  25                  30          


Val Gln Ala Gln Val Lys Cys Cys Gly Trp Val Ser Phe Tyr Asn Trp 
        35                  40                  45              


Thr Asp Asn Ala Glu Leu Met Asn Arg Pro Glu Val Thr Tyr Pro Cys 
    50                  55                  60                  


Ser Cys Glu Val Lys Gly Glu Glu Asp Asn Ser Leu Ser Val Arg Lys 
65                  70                  75                  80  


Gly Phe Cys Glu Ala Pro Gly Asn Arg Thr Gln Ser Gly Asn His Pro 
                85                  90                  95      


Glu Asp Trp Pro Val Tyr Gln Glu Gly Cys Met Glu Lys Val Gln Ala 
            100                 105                 110         


Trp Leu Gln Glu Asn Leu 
        115             


<210>  208
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  208

Thr Pro Glu Val Lys Val Ala Cys Ser Glu Asp Val Asp Leu Pro Cys 
1               5                   10                  15      


Thr Ala Pro Trp Asp Pro Gln Val Pro Tyr Thr Val Ser Trp Val Lys 
            20                  25                  30          


Leu Leu Glu Gly Gly Glu Glu Arg Met Glu Thr Pro Gln Glu Asp His 
        35                  40                  45              


Leu Arg Gly Gln His Tyr His Gln Lys Gly Gln Asn Gly Ser Phe Asp 
    50                  55                  60                  


Ala Pro Asn Glu Arg Pro Tyr Ser Leu Lys Ile Arg Asn Thr Thr Ser 
65                  70                  75                  80  


Cys Asn Ser Gly Thr Tyr Arg Cys Thr Leu Gln Asp Pro Asp Gly Gln 
                85                  90                  95      


Arg Asn Leu Ser Gly Lys Val Ile Leu Arg Val Thr Gly Cys Pro Ala 
            100                 105                 110         


Gln Arg Lys Glu Glu Thr Phe Lys Lys Tyr Arg Ala Glu 
        115                 120                 125 


<210>  209
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  209

Lys Asp Ser Glu Ile Phe Thr Val Asn Gly Ile Leu Gly Glu Ser Val 
1               5                   10                  15      


Thr Phe Pro Val Asn Ile Gln Glu Pro Arg Gln Val Lys Ile Ile Ala 
            20                  25                  30          


Trp Thr Ser Lys Thr Ser Val Ala Tyr Val Thr Pro Gly Asp Ser Glu 
        35                  40                  45              


Thr Ala Pro Val Val Thr Val Thr His Arg Asn Tyr Tyr Glu Arg Ile 
    50                  55                  60                  


His Ala Leu Gly Pro Asn Tyr Asn Leu Val Ile Ser Asp Leu Arg Met 
65                  70                  75                  80  


Glu Asp Ala Gly Asp Tyr Lys Ala Asp Ile Asn Thr Gln Ala Asp Pro 
                85                  90                  95      


Tyr Thr Thr Thr Lys Arg Tyr Asn Leu Gln Ile Tyr Arg Arg Leu Gly 
            100                 105                 110         


Lys Pro Lys Ile Thr Gln Ser Leu Met Ala Ser Val Asn Ser Thr Cys 
        115                 120                 125             


Asn Val Thr Leu Thr Cys Ser Val Glu Lys Glu Glu Lys Asn Val Thr 
    130                 135                 140                 


Tyr Asn Trp Ser Pro Leu Gly Glu Glu Gly Asn Val Leu Gln Ile Phe 
145                 150                 155                 160 


Gln Thr Pro Glu Asp Gln Glu Leu Thr Tyr Thr Cys Thr Ala Gln Asn 
                165                 170                 175     


Pro Val Ser Asn Asn Ser Asp Ser Ile Ser Ala Arg Gln Leu Cys Ala 
            180                 185                 190         


Asp Ile Ala Met Gly Phe Arg Thr His His Thr Gly 
        195                 200                 


<210>  210
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  210

Ala Pro Leu Lys Ile Gln Ala Tyr Phe Asn Glu Thr Ala Asp Leu Pro 
1               5                   10                  15      


Cys Gln Phe Ala Asn Ser Gln Asn Gln Ser Leu Ser Glu Leu Val Val 
            20                  25                  30          


Phe Trp Gln Asp Gln Glu Asn Leu Val Leu Asn Glu Val Tyr Leu Gly 
        35                  40                  45              


Lys Glu Lys Phe Asp Ser Val His Ser Lys Tyr Met Gly Arg Thr Ser 
    50                  55                  60                  


Phe Asp Ser Asp Ser Trp Thr Leu Arg Leu His Asn Leu Gln Ile Lys 
65                  70                  75                  80  


Asp Lys Gly Leu Tyr Gln Cys Ile Ile His His Lys Lys Pro Thr Gly 
                85                  90                  95      


Met Ile Arg Ile His Gln Met Asn Ser Glu Leu Ser Val Leu Ala Asn 
            100                 105                 110         


Phe Ser Gln Pro Glu Ile Val Pro Ile Ser Asn Ile Thr Glu Asn Val 
        115                 120                 125             


Tyr Ile Asn Leu Thr Cys Ser Ser Ile His Gly Tyr Pro Glu Pro Lys 
    130                 135                 140                 


Lys Met Ser Val Leu Leu Arg Thr Lys Asn Ser Thr Ile Glu Tyr Asp 
145                 150                 155                 160 


Gly Ile Met Gln Lys Ser Gln Asp Asn Val Thr Glu Leu Tyr Asp Val 
                165                 170                 175     


Ser Ile Ser Leu Ser Val Ser Phe Pro Asp Val Thr Ser Asn Met Thr 
            180                 185                 190         


Ile Phe Cys Ile Leu Glu Thr Asp Lys Thr Arg Leu Leu Ser Ser Pro 
        195                 200                 205             


Phe Ser Ile Glu Leu Glu Asp Pro Gln Pro Pro Pro Asp His Ile Pro 
    210                 215                 220                 


<210>  211
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  211

Ser Gln Phe Arg Val Ser Pro Leu Asp Arg Thr Trp Asn Leu Gly Glu 
1               5                   10                  15      


Thr Val Glu Leu Lys Cys Gln Val Leu Leu Ser Asn Pro Thr Ser Gly 
            20                  25                  30          


Cys Ser Trp Leu Phe Gln Pro Arg Gly Ala Ala Ala Ser Pro Thr Phe 
        35                  40                  45              


Leu Leu Tyr Leu Ser Gln Asn Lys Pro Lys Ala Ala Glu Gly Leu Asp 
    50                  55                  60                  


Thr Gln Arg Phe Ser Gly Lys Arg Leu Gly Asp Thr Phe Val Leu Thr 
65                  70                  75                  80  


Leu Ser Asp Phe Arg Arg Glu Asn Glu Gly Cys Tyr Phe Cys Ser Ala 
                85                  90                  95      


Leu Ser Asn Ser Ile Met Tyr Phe Ser His Phe Val Pro Val Phe Leu 
            100                 105                 110         


Pro Ala Lys Pro Thr Thr Thr Pro Ala Pro Arg Pro Pro Thr Pro Ala 
        115                 120                 125             


Pro Thr Ile Ala Ser Gln Pro Leu Ser Leu Arg Pro Glu Ala Cys Arg 
    130                 135                 140                 


Pro Ala Ala Gly Gly Ala Val His Thr Arg Gly Leu Asp Phe Ala Cys 
145                 150                 155                 160 


Asp 
    


<210>  212
<211>  149
<212>  PRT
<213>  Homo Sapiens

<400>  212

Leu Gln Gln Thr Pro Ala Tyr Ile Lys Val Gln Thr Asn Lys Met Val 
1               5                   10                  15      


Met Leu Ser Cys Glu Ala Lys Ile Ser Leu Ser Asn Met Arg Ile Tyr 
            20                  25                  30          


Trp Leu Arg Gln Arg Gln Ala Pro Ser Ser Asp Ser His His Glu Phe 
        35                  40                  45              


Leu Ala Leu Trp Asp Ser Ala Lys Gly Thr Ile His Gly Glu Glu Val 
    50                  55                  60                  


Glu Gln Glu Lys Ile Ala Val Phe Arg Asp Ala Ser Arg Phe Ile Leu 
65                  70                  75                  80  


Asn Leu Thr Ser Val Lys Pro Glu Asp Ser Gly Ile Tyr Phe Cys Met 
                85                  90                  95      


Ile Val Gly Ser Pro Glu Leu Thr Phe Gly Lys Gly Thr Gln Leu Ser 
            100                 105                 110         


Val Val Asp Phe Leu Pro Thr Thr Ala Gln Pro Thr Lys Lys Ser Thr 
        115                 120                 125             


Leu Lys Lys Arg Val Cys Arg Leu Pro Arg Pro Glu Thr Gln Lys Gly 
    130                 135                 140                 


Pro Leu Cys Ser Pro 
145                 


<210>  213
<211>  153
<212>  PRT
<213>  Homo Sapiens

<400>  213

Asn Ser Val Leu Gln Gln Thr Pro Ala Tyr Ile Lys Val Gln Thr Asn 
1               5                   10                  15      


Lys Met Val Met Leu Ser Cys Glu Ala Lys Ile Ser Leu Ser Asn Met 
            20                  25                  30          


Cys Ile Tyr Trp Leu Arg Gln Arg Gln Ala Pro Ser Ser Asp Ser His 
        35                  40                  45              


His Glu Phe Leu Thr Leu Trp Asp Ser Ala Lys Gly Thr Ile His Gly 
    50                  55                  60                  


Glu Glu Val Glu Gln Glu Lys Ile Ala Val Phe Arg Asp Ala Ser Arg 
65                  70                  75                  80  


Phe Ile Leu Asn Leu Thr Ser Val Lys Pro Glu Asp Ser Gly Ile Tyr 
                85                  90                  95      


Phe Cys Met Ile Val Gly Ser Pro Glu Leu Thr Phe Gly Lys Gly Thr 
            100                 105                 110         


Gln Leu Ser Val Val Val Asp Phe Leu Pro Thr Thr Ala Gln Pro Thr 
        115                 120                 125             


Lys Lys Ser Thr Leu Lys Lys Arg Val Cys Arg Leu Pro Arg Pro Glu 
    130                 135                 140                 


Thr Gln Lys Gly Pro Leu Cys Ser Pro 
145                 150             


<210>  214
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  214

Ser His Lys Asp Glu Val Ile Lys Glu Val Gln Glu Phe Tyr Lys Asp 
1               5                   10                  15      


Thr Tyr Asn Lys Leu Lys Thr Lys Asp Glu Pro Gln Arg Glu Thr Leu 
            20                  25                  30          


Lys Ala Ile His Tyr Ala Leu Asn Cys Cys Gly Leu Ala Gly Gly Val 
        35                  40                  45              


Glu Gln Phe Ile Ser Asp Ile Cys Pro Lys Lys Asp Val Leu Glu Thr 
    50                  55                  60                  


Phe Thr Val Lys Ser Cys Pro Asp Ala Ile Lys Glu Val Phe Asp Asn 
65                  70                  75                  80  


Lys Phe His Ile 
                


<210>  215
<211>  381
<212>  PRT
<213>  Homo Sapiens

<400>  215

Val Trp Glu Lys Thr Val Asn Thr Glu Glu Asn Val Tyr Ala Thr Leu 
1               5                   10                  15      


Gly Ser Asp Val Asn Leu Thr Cys Gln Thr Gln Thr Val Gly Phe Phe 
            20                  25                  30          


Val Gln Met Gln Trp Ser Lys Val Thr Asn Lys Ile Asp Leu Ile Ala 
        35                  40                  45              


Val Tyr His Pro Gln Tyr Gly Phe Tyr Cys Ala Tyr Gly Arg Pro Cys 
    50                  55                  60                  


Glu Ser Leu Val Thr Phe Thr Glu Thr Pro Glu Asn Gly Ser Lys Trp 
65                  70                  75                  80  


Thr Leu His Leu Arg Asn Met Ser Cys Ser Val Ser Gly Arg Tyr Glu 
                85                  90                  95      


Cys Met Leu Val Leu Tyr Pro Glu Gly Ile Gln Thr Lys Ile Tyr Asn 
            100                 105                 110         


Leu Leu Ile Gln Thr His Val Thr Ala Asp Glu Trp Asn Ser Asn His 
        115                 120                 125             


Thr Ile Glu Ile Glu Ile Asn Gln Thr Leu Glu Ile Pro Cys Phe Gln 
    130                 135                 140                 


Asn Ser Ser Ser Lys Ile Ser Ser Glu Phe Thr Tyr Ala Trp Ser Val 
145                 150                 155                 160 


Glu Asp Asn Gly Thr Gln Glu Thr Leu Ile Ser Gln Asn His Leu Ile 
                165                 170                 175     


Ser Asn Ser Thr Leu Leu Lys Asp Arg Val Lys Leu Gly Thr Asp Tyr 
            180                 185                 190         


Arg Leu His Leu Ser Pro Val Gln Ile Phe Asp Asp Gly Arg Lys Phe 
        195                 200                 205             


Ser Cys His Ile Arg Val Gly Pro Asn Lys Ile Leu Arg Ser Ser Thr 
    210                 215                 220                 


Thr Val Lys Val Phe Ala Lys Pro Glu Ile Pro Val Ile Val Glu Asn 
225                 230                 235                 240 


Asn Ser Thr Asp Val Leu Val Glu Arg Arg Phe Thr Cys Leu Leu Lys 
                245                 250                 255     


Asn Val Phe Pro Lys Ala Asn Ile Thr Trp Phe Ile Asp Gly Ser Phe 
            260                 265                 270         


Leu His Asp Glu Lys Glu Gly Ile Tyr Ile Thr Asn Glu Glu Arg Lys 
        275                 280                 285             


Gly Lys Asp Gly Phe Leu Glu Leu Lys Ser Val Leu Thr Arg Val His 
    290                 295                 300                 


Ser Asn Lys Pro Ala Gln Ser Asp Asn Leu Thr Ile Trp Cys Met Ala 
305                 310                 315                 320 


Leu Ser Pro Val Pro Gly Asn Lys Val Trp Asn Ile Ser Ser Glu Lys 
                325                 330                 335     


Ile Thr Phe Leu Leu Gly Ser Glu Ile Ser Ser Thr Asp Pro Pro Leu 
            340                 345                 350         


Ser Val Thr Glu Ser Thr Leu Asp Thr Gln Pro Ser Pro Ala Ser Ser 
        355                 360                 365             


Val Ser Pro Ala Ser Lys Asn Val Phe Thr Leu Ser Tyr 
    370                 375                 380     


<210>  216
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  216

Asp Gly Gly Phe Asp Leu Ser Asp Ala Leu Pro Asp Asn Glu Asn Lys 
1               5                   10                  15      


Lys Pro Thr Ala Ile Pro Lys Lys Pro Ser Ala Gly Asp Asp Phe Asp 
            20                  25                  30          


Leu Gly Asp Ala Val Val Asp Gly Glu Asn Asp Asp Pro Arg Pro Pro 
        35                  40                  45              


Asn Pro Pro Lys Pro Met Pro Asn Pro Asn Pro Asn His Pro Ser Ser 
    50                  55                  60                  


Ser Gly Ser Phe Ser Asp Ala Asp Leu Ala Asp Gly Val Ser Gly Gly 
65                  70                  75                  80  


Glu Gly Lys Gly Gly Ser Asp Gly Gly Gly Ser His Arg Lys Glu Gly 
                85                  90                  95      


Glu Glu Ala Asp 
            100 


<210>  217
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  217

Asp Trp Val Ile Pro Pro Ile Ser Cys Pro Glu Asn Glu Lys Gly Pro 
1               5                   10                  15      


Phe Pro Lys Asn Leu Val Gln Ile Lys Ser Asn Lys Asp Lys Glu Gly 
            20                  25                  30          


Lys Val Phe Tyr Ser Ile Thr Gly Gln Gly Ala Asp Thr Pro Pro Val 
        35                  40                  45              


Gly Val Phe Ile Ile Glu Arg Glu Thr Gly Trp Leu Lys Val Thr Glu 
    50                  55                  60                  


Pro Leu Asp Arg Glu Arg Ile Ala Thr Tyr Thr Leu Phe Ser His Ala 
65                  70                  75                  80  


Val Ser Ser Asn Gly Asn Ala Val Glu Asp Pro Met Glu Ile Leu Ile 
                85                  90                  95      


Thr Val Thr Asp Gln Asn Asp Asn Lys Pro Glu Phe Thr Gln Glu Val 
            100                 105                 110         


Phe Lys Gly Ser Val Met Glu Gly Ala Leu Pro Gly Thr Ser Val Met 
        115                 120                 125             


Glu Val Thr Ala Thr Asp Ala Asp Asp Asp Val Asn Thr Tyr Asn Ala 
    130                 135                 140                 


Ala Ile Ala Tyr Thr Ile Leu Ser Gln Asp Pro Glu Leu Pro Asp Lys 
145                 150                 155                 160 


Asn Met Phe Thr Ile Asn Arg Asn Thr Gly Val Ile Ser Val Val Thr 
                165                 170                 175     


Thr Gly Leu Asp Arg Glu Ser Phe Pro Ala Tyr Thr Leu Val Val Gln 
            180                 185                 190         


Ala Ala Asp Leu Gln Gly Glu Gly Leu Ser Thr Thr Ala Thr Ala Val 
        195                 200                 205             


Ile Thr Val Thr Asp Thr Asn Asp Asn Pro Pro Ile Phe Asn Pro Thr 
    210                 215                 220                 


Thr Tyr Lys Gly Gln Val Pro Glu Asn Glu Ala Asn Val Val Ile Thr 
225                 230                 235                 240 


Thr Leu Lys Val Thr Asp Ala Asp Ala Pro Asn Thr Pro Ala Trp Glu 
                245                 250                 255     


Ala Val Tyr Thr Ile Leu Asn Asp Asp Gly Gly Gln Phe Val Val Thr 
            260                 265                 270         


Thr Asn Pro Val Asn Asn Asp Gly Ile Leu Lys Thr Ala Lys Gly Leu 
        275                 280                 285             


Asp Phe Glu Ala Lys Gln Gln Tyr Ile Leu His Val Ala Val Thr Asn 
    290                 295                 300                 


Val Val Pro Phe Glu Val Ser Leu Thr Thr Ser Thr Ala Thr Val Thr 
305                 310                 315                 320 


Val Asp Val Leu Asp Val Asn Glu Ala Pro Ile Phe Val Pro Pro Glu 
                325                 330                 335     


Lys Arg Val Glu Val Ser Glu Asp Phe Gly Val Gly Gln Glu Ile Thr 
            340                 345                 350         


Ser Tyr Thr Ala Gln Glu Pro Asp Thr Phe Met Glu Gln Lys Ile Thr 
        355                 360                 365             


Tyr Arg Ile Trp Arg Asp Thr Ala Asn Trp Leu Glu Ile Asn Pro Asp 
    370                 375                 380                 


Thr Gly Ala Ile Ser Thr Arg Ala Glu Leu Asp Arg Glu Asp Phe Glu 
385                 390                 395                 400 


His Val Lys Asn Ser Thr Tyr Thr Ala Leu Ile Ile Ala Thr Asp Asn 
                405                 410                 415     


Gly Ser Pro Val Ala Thr Gly Thr Gly Thr Leu Leu Leu Ile Leu Ser 
            420                 425                 430         


Asp Val Asn Asp Asn Ala Pro 
        435                 


<210>  218
<211>  559
<212>  PRT
<213>  Homo Sapiens

<400>  218

Gly Trp Met Trp Asn Gln Phe Phe Leu Leu Glu Glu Tyr Thr Gly Ser 
1               5                   10                  15      


Asp Tyr Gln Tyr Val Gly Lys Leu His Ser Asp Gln Asp Lys Gly Asp 
            20                  25                  30          


Gly Ser Leu Lys Tyr Ile Leu Ser Gly Asp Gly Ala Gly Thr Leu Phe 
        35                  40                  45              


Ile Ile Asp Glu Lys Thr Gly Asp Ile His Ala Thr Arg Arg Ile Asp 
    50                  55                  60                  


Arg Glu Glu Lys Ala Phe Tyr Thr Leu Arg Ala Gln Ala Ile Asn Arg 
65                  70                  75                  80  


Arg Thr Leu Arg Pro Val Glu Pro Glu Ser Glu Phe Val Ile Lys Ile 
                85                  90                  95      


His Asp Ile Asn Asp Asn Glu Pro Thr Phe Pro Glu Glu Ile Tyr Thr 
            100                 105                 110         


Ala Ser Val Pro Glu Met Ser Val Val Gly Thr Ser Val Val Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Ser Tyr Gly Asn Ser Ala Arg Val 
    130                 135                 140                 


Ile Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Glu Pro Glu 
145                 150                 155                 160 


Thr Gly Ile Ile Arg Thr Ala Leu Pro Asn Met Asn Arg Glu Asn Arg 
                165                 170                 175     


Glu Gln Tyr Gln Val Val Ile Gln Ala Lys Asp Met Gly Gly Gln Met 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Thr Val Asn Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Arg Phe Pro Gln Asn Thr Ile His Leu Arg Val 
    210                 215                 220                 


Leu Glu Ser Ser Pro Val Gly Thr Ala Ile Gly Ser Val Lys Ala Thr 
225                 230                 235                 240 


Asp Ala Asp Thr Gly Lys Asn Ala Glu Val Glu Tyr Arg Ile Ile Asp 
                245                 250                 255     


Gly Asp Gly Thr Asp Met Phe Asp Ile Val Thr Glu Lys Asp Thr Gln 
            260                 265                 270         


Glu Gly Ile Ile Thr Val Lys Lys Pro Leu Asp Tyr Glu Ser Arg Arg 
        275                 280                 285             


Leu Tyr Thr Leu Lys Val Glu Ala Glu Asn Thr His Val Asp Pro Arg 
    290                 295                 300                 


Phe Tyr Tyr Leu Gly Pro Phe Lys Asp Thr Thr Ile Val Lys Ile Ser 
305                 310                 315                 320 


Ile Glu Asp Val Asp Glu Pro Pro Val Phe Ser Arg Ser Ser Tyr Leu 
                325                 330                 335     


Phe Glu Val His Glu Asp Ile Glu Val Gly Thr Ile Ile Gly Thr Val 
            340                 345                 350         


Met Ala Arg Asp Pro Asp Ser Ile Ser Ser Pro Ile Arg Phe Ser Leu 
        355                 360                 365             


Asp Arg His Thr Asp Leu Asp Arg Ile Phe Asn Ile His Ser Gly Asn 
    370                 375                 380                 


Gly Ser Leu Tyr Thr Ser Lys Pro Leu Asp Arg Glu Leu Ser Gln Trp 
385                 390                 395                 400 


His Asn Leu Thr Val Ile Ala Ala Glu Ile Asn Asn Pro Lys Glu Thr 
                405                 410                 415     


Thr Arg Val Ala Val Phe Val Arg Ile Leu Asp Val Asn Asp Asn Ala 
            420                 425                 430         


Pro Gln Phe Ala Val Phe Tyr Asp Thr Phe Val Cys Glu Asn Ala Arg 
        435                 440                 445             


Pro Gly Gln Leu Ile Gln Thr Ile Ser Ala Val Asp Lys Asp Asp Pro 
    450                 455                 460                 


Leu Gly Gly Gln Lys Phe Phe Phe Ser Leu Ala Ala Val Asn Pro Asn 
465                 470                 475                 480 


Phe Thr Val Gln Asp Asn Glu Asp Asn Thr Ala Arg Ile Leu Thr Arg 
                485                 490                 495     


Lys Asn Gly Phe Asn Arg His Glu Ile Ser Thr Tyr Leu Leu Pro Val 
            500                 505                 510         


Val Ile Ser Asp Asn Asp Tyr Pro Ile Gln Ser Ser Thr Gly Thr Leu 
        515                 520                 525             


Thr Ile Arg Val Cys Ala Cys Asp Ser Gln Gly Asn Met Gln Ser Cys 
    530                 535                 540                 


Ser Ala Glu Ala Leu Leu Leu Pro Ala Gly Leu Ser Thr Gly Ala 
545                 550                 555                 


<210>  219
<211>  564
<212>  PRT
<213>  Homo Sapiens

<400>  219

Gly Trp Val Trp Asn Gln Phe Phe Val Ile Glu Glu Tyr Thr Gly Pro 
1               5                   10                  15      


Asp Pro Val Leu Val Gly Arg Leu His Ser Asp Ile Asp Ser Gly Asp 
            20                  25                  30          


Gly Asn Ile Lys Tyr Ile Leu Ser Gly Glu Gly Ala Gly Thr Ile Phe 
        35                  40                  45              


Val Ile Asp Asp Lys Ser Gly Asn Ile His Ala Thr Lys Thr Leu Asp 
    50                  55                  60                  


Arg Glu Glu Arg Ala Gln Tyr Thr Leu Met Ala Gln Ala Val Asp Arg 
65                  70                  75                  80  


Asp Thr Asn Arg Pro Leu Glu Pro Pro Ser Glu Phe Ile Val Lys Val 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Pro Pro Glu Phe Leu His Glu Thr Tyr His 
            100                 105                 110         


Ala Asn Val Pro Glu Arg Ser Asn Val Gly Thr Ser Val Ile Gln Val 
        115                 120                 125             


Thr Ala Ser Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Lys Leu 
    130                 135                 140                 


Val Tyr Ser Ile Leu Glu Gly Gln Pro Tyr Phe Ser Val Glu Ala Gln 
145                 150                 155                 160 


Thr Gly Ile Ile Arg Thr Ala Leu Pro Asn Met Asp Arg Glu Ala Lys 
                165                 170                 175     


Glu Glu Tyr His Val Val Ile Gln Ala Lys Asp Met Gly Gly His Met 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Lys Val Met Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Lys Phe Pro Gln Ser Val Tyr Gln Met Ser Val 
    210                 215                 220                 


Ser Glu Ala Ala Val Pro Gly Glu Glu Val Gly Arg Val Lys Ala Lys 
225                 230                 235                 240 


Asp Pro Asp Ile Gly Glu Asn Gly Leu Val Thr Tyr Asn Ile Val Asp 
                245                 250                 255     


Gly Asp Gly Met Glu Ser Phe Glu Ile Thr Thr Asp Tyr Glu Thr Gln 
            260                 265                 270         


Glu Gly Val Ile Lys Leu Lys Lys Pro Val Asp Phe Glu Thr Lys Arg 
        275                 280                 285             


Ala Tyr Ser Leu Lys Val Glu Ala Ala Asn Val His Ile Asp Pro Lys 
    290                 295                 300                 


Phe Ile Ser Asn Gly Pro Phe Lys Asp Thr Val Thr Val Lys Ile Ala 
305                 310                 315                 320 


Val Glu Asp Ala Asp Glu Pro Pro Met Phe Leu Ala Pro Ser Tyr Ile 
                325                 330                 335     


His Glu Val Gln Glu Asn Ala Ala Ala Gly Thr Val Val Gly Arg Val 
            340                 345                 350         


His Ala Lys Asp Pro Asp Ala Ala Asn Ser Pro Ile Arg Tyr Ser Ile 
        355                 360                 365             


Asp Arg His Thr Asp Leu Asp Arg Phe Phe Thr Ile Asn Pro Glu Asp 
    370                 375                 380                 


Gly Phe Ile Lys Thr Thr Lys Pro Leu Asp Arg Glu Glu Thr Ala Trp 
385                 390                 395                 400 


Leu Asn Ile Thr Val Phe Ala Ala Glu Ile His Asn Arg His Gln Glu 
                405                 410                 415     


Ala Lys Val Pro Val Ala Ile Arg Val Leu Asp Val Asn Asp Asn Ala 
            420                 425                 430         


Pro Lys Phe Ala Ala Pro Tyr Glu Gly Phe Ile Cys Glu Ser Asp Gln 
        435                 440                 445             


Thr Lys Pro Leu Ser Asn Gln Pro Ile Val Thr Ile Ser Ala Asp Asp 
    450                 455                 460                 


Lys Asp Asp Thr Ala Asn Gly Pro Arg Phe Ile Phe Ser Leu Pro Pro 
465                 470                 475                 480 


Glu Ile Ile His Asn Pro Asn Phe Thr Val Arg Asp Asn Arg Asp Asn 
                485                 490                 495     


Thr Ala Gly Val Tyr Ala Arg Arg Gly Gly Phe Ser Arg Gln Lys Gln 
            500                 505                 510         


Asp Leu Tyr Leu Leu Pro Ile Val Ile Ser Asp Gly Gly Ile Pro Pro 
        515                 520                 525             


Met Ser Ser Thr Asn Thr Leu Thr Ile Lys Val Cys Gly Cys Asp Val 
    530                 535                 540                 


Asn Gly Ala Leu Leu Ser Cys Asn Ala Glu Ala Tyr Ile Leu Asn Ala 
545                 550                 555                 560 


Gly Leu Ser Thr 
                


<210>  220
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  220

Gly Trp Val Trp Asn Gln Phe Phe Val Leu Glu Glu Tyr Val Gly Ser 
1               5                   10                  15      


Glu Pro Gln Tyr Val Gly Lys Leu His Ser Asp Leu Asp Lys Gly Glu 
            20                  25                  30          


Gly Thr Val Lys Tyr Thr Leu Ser Gly Asp Gly Ala Gly Thr Val Phe 
        35                  40                  45              


Thr Ile Asp Glu Thr Thr Gly Asp Ile His Ala Ile Arg Ser Leu Asp 
    50                  55                  60                  


Arg Glu Glu Lys Pro Phe Tyr Thr Leu Arg Ala Gln Ala Val Asp Ile 
65                  70                  75                  80  


Glu Thr Arg Lys Pro Leu Glu Pro Glu Ser Glu Phe Ile Ile Lys Val 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Glu Pro Lys Phe Leu Asp Gly Pro Tyr Val 
            100                 105                 110         


Ala Thr Val Pro Glu Met Ser Pro Val Gly Ala Tyr Val Leu Gln Val 
        115                 120                 125             


Lys Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Arg Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Ile Asp Pro Lys 
145                 150                 155                 160 


Thr Gly Val Ile Arg Thr Ala Leu Pro Asn Met Asp Arg Glu Val Lys 
                165                 170                 175     


Glu Gln Tyr Gln Val Leu Ile Gln Ala Lys Asp Met Gly Gly Gln Leu 
            180                 185                 190         


Gly Gly Leu Ala Gly Thr Thr Ile Val Asn Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Arg Phe Pro Lys Ser Ile Phe His Leu Lys Val 
    210                 215                 220                 


Pro Glu Ser Ser Pro Ile Gly Ser Ala Ile Gly Arg Ile Arg Ala Val 
225                 230                 235                 240 


Asp Pro Asp Phe Gly Gln Asn Ala Glu Ile Glu Tyr Asn Ile Val Pro 
                245                 250                 255     


Gly Asp Gly Gly Asn Leu Phe Asp Ile Val Thr Asp Glu Asp Thr Gln 
            260                 265                 270         


Glu Gly Val Ile Lys Leu Lys Lys Pro Leu Asp Phe Glu Thr Lys Lys 
        275                 280                 285             


Ala Tyr Thr Phe Lys Val Glu Ala Ser Asn Leu His Leu Asp His Arg 
    290                 295                 300                 


Phe His Ser Ala Gly Pro Phe Lys Asp Thr Ala Thr Val Lys Ile Ser 
305                 310                 315                 320 


Val Leu Asp Val Asp Glu Pro Pro Val Phe Ser Lys Pro Leu Tyr Thr 
                325                 330                 335     


Met Glu Val Tyr Glu Asp Thr Pro Val Gly Thr Ile Ile Gly Ala Val 
            340                 345                 350         


Thr Ala Gln Asp Leu Asp Val Gly Ser Ser Ala Val Arg Tyr Phe Ile 
        355                 360                 365             


Asp Trp Lys Ser Asp Gly Asp Ser Tyr Phe Thr Ile Asp Gly Asn Glu 
    370                 375                 380                 


Gly Thr Ile Ala Thr Asn Glu Leu Leu Asp Arg Glu Ser Thr Ala Gln 
385                 390                 395                 400 


Tyr Asn Phe Ser Ile Ile Ala Ser Lys Val Ser Asn Pro Leu Leu Thr 
                405                 410                 415     


Ser Lys Val Asn Ile Leu Ile Asn Val Leu Asp Val Asn Glu Phe Pro 
            420                 425                 430         


Pro Glu Ile Ser Val Pro Tyr Glu Thr Ala Val Cys Glu Asn Ala Lys 
        435                 440                 445             


Pro Gly Gln Ile Ile Gln Ile Val Ser Ala Ala Asp Arg Asp Leu Ser 
    450                 455                 460                 


Pro Ala Gly Gln Gln Phe Ser Phe Arg Leu Ser Pro Glu Ala Ala Ile 
465                 470                 475                 480 


Lys Pro Asn Phe Thr Val Arg Asp Phe Arg Asn Asn Thr Ala Gly Ile 
                485                 490                 495     


Glu Thr Arg Arg Asn Gly Tyr Ser Arg Arg Gln Gln Glu Leu Tyr Phe 
            500                 505                 510         


Leu Pro Val Val Ile Glu Asp Ser Ser Tyr Pro Val Gln Ser Ser Thr 
        515                 520                 525             


Asn Thr Met Thr Ile Arg Val Cys Arg Cys Asp Ser Asp Gly Thr Ile 
    530                 535                 540                 


Leu Ser Cys Asn Val Glu Ala Ile Phe Leu Pro 
545                 550                 555 


<210>  221
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  221

Ser Ile Val Val Ser Pro Ile Leu Ile Pro Glu Asn Gln Arg Gln Pro 
1               5                   10                  15      


Phe Pro Arg Asp Val Gly Lys Val Val Asp Ser Asp Arg Pro Glu Arg 
            20                  25                  30          


Ser Lys Phe Arg Leu Thr Gly Lys Gly Val Asp Gln Glu Pro Lys Gly 
        35                  40                  45              


Ile Phe Arg Ile Asn Glu Asn Thr Gly Ser Val Ser Met Thr Arg Thr 
    50                  55                  60                  


Leu Asp Arg Glu Val Ile Ala Val Tyr Gln Leu Phe Val Glu Thr Thr 
65                  70                  75                  80  


Asp Val Asn Gly Lys Thr Leu Glu Gly Pro Val Pro Leu Glu Val Ile 
                85                  90                  95      


Val Ile Asp Gln Asn Asp Asn Arg Pro Ile Phe Arg Glu Gly Pro Tyr 
            100                 105                 110         


Ile Gly His Val Met Glu Gly Ser Pro Thr Gly Thr Thr Val Met Arg 
        115                 120                 125             


Met Thr Ala Phe Asp Ala Asp Asp Pro Ala Thr Asp Asn Ala Leu Leu 
    130                 135                 140                 


Arg Tyr Asn Ile Arg Arg Gln Thr Pro Asp Lys Pro Ser Pro Asn Met 
145                 150                 155                 160 


Phe Tyr Ile Asp Pro Glu Lys Gly Asp Ile Val Thr Val Val Ser Pro 
                165                 170                 175     


Ala Leu Leu Asp Arg Glu Thr Leu Glu Asn Pro Lys Tyr Glu Leu Ile 
            180                 185                 190         


Ile Glu Ala Gln Asp Met Ala Gly Leu Asp Val Gly Leu Thr Gly Thr 
        195                 200                 205             


Ala Thr Ala Thr Ile Met Ile Asp Asp Lys Asn Asp His Ser Pro Lys 
    210                 215                 220                 


Phe Thr Lys Lys Glu Phe Gln Ala Thr Val Glu Glu Gly Ala Val Gly 
225                 230                 235                 240 


Val Ile Val Asn Leu Thr Val Glu Asp Lys Asp Asp Pro Ala Thr Gly 
                245                 250                 255     


Ala Trp Arg Ala Ala Tyr Thr Ile Ile Asn Gly Asn Pro Gly Gln Ser 
            260                 265                 270         


Phe Glu Ile His Thr Asn Pro Gln Thr Asn Glu Gly Met Leu Ser Val 
        275                 280                 285             


Val Lys Pro Leu Asp Tyr Glu Ile Ser Ala Phe His Thr Leu Leu Ile 
    290                 295                 300                 


Lys Val Glu Asn Glu Asp Pro Leu Val Pro Asp Val Ser Tyr Gly Pro 
305                 310                 315                 320 


Ser Ser Thr Ala Thr Val His Ile Thr Val Leu Asp Val Asn Glu Gly 
                325                 330                 335     


Pro Val Phe Tyr Pro Asp Pro Met Met Val Thr Arg Gln Glu Asp Leu 
            340                 345                 350         


Ser Val Gly Ser Val Leu Leu Thr Val Asn Ala Thr Asp Pro Asp Ser 
        355                 360                 365             


Leu Gln His Gln Thr Ile Arg Tyr Ser Val Tyr Lys Asp Pro Ala Gly 
    370                 375                 380                 


Trp Leu Asn Ile Asn Pro Ile Asn Gly Thr Val Asp Thr Thr Ala Val 
385                 390                 395                 400 


Leu Asp Arg Glu Ser Thr Phe Val Asp Asn Ser Val Tyr Thr Ala Leu 
                405                 410                 415     


Phe Leu Ala Ile Asp Ser Gly Asn Pro Pro Ala Thr Gly Thr Gly Thr 
            420                 425                 430         


Leu Leu Ile Thr Leu Glu Asp Val Asn Asp Asn Ala Pro Phe Ile Tyr 
        435                 440                 445             


Pro Thr Val Ala Glu Val Cys Asp Asp Ala Lys Asn Leu Ser Val Val 
    450                 455                 460                 


Ile Leu Gly Ala Ser Asp Lys Asp Leu His Pro Asn Thr Asp Pro Phe 
465                 470                 475                 480 


Lys Phe Glu Ile His Lys Gln Ala Val Pro Asp Lys Val Trp Lys Ile 
                485                 490                 495     


Ser Lys Ile Asn Asn Thr His Ala Leu Val Ser Leu Leu Gln Asn Leu 
            500                 505                 510         


Asn Lys Ala Asn Tyr Asn Leu Pro Ile Met Val Thr Asp Ser Gly Lys 
        515                 520                 525             


Pro Pro Met Thr Asn Ile Thr Asp Leu Arg Val Gln Val Cys Ser Cys 
    530                 535                 540                 


Arg Asn Ser Lys Val Asp Cys Asn Ala Ala Gly 
545                 550                 555 


<210>  222
<211>  546
<212>  PRT
<213>  Homo Sapiens

<400>  222

Leu Pro Tyr Pro Leu Val Gln Ile Lys Ser Asp Lys Gln Gln Leu Gly 
1               5                   10                  15      


Ser Val Ile Tyr Ser Ile Gln Gly Pro Gly Val Asp Glu Glu Pro Arg 
            20                  25                  30          


Gly Val Phe Ser Ile Asp Lys Phe Thr Gly Lys Val Phe Leu Asn Ala 
        35                  40                  45              


Met Leu Asp Arg Glu Lys Thr Asp Arg Phe Arg Leu Arg Ala Phe Ala 
    50                  55                  60                  


Leu Asp Leu Gly Gly Ser Thr Leu Glu Asp Pro Thr Asp Leu Glu Ile 
65                  70                  75                  80  


Val Val Val Asp Gln Asn Asp Asn Arg Pro Ala Phe Leu Gln Glu Ala 
                85                  90                  95      


Phe Thr Gly Arg Val Leu Glu Gly Ala Val Pro Gly Thr Tyr Val Thr 
            100                 105                 110         


Arg Ala Glu Ala Thr Asp Ala Asp Asp Pro Glu Thr Asp Asn Ala Ala 
        115                 120                 125             


Leu Arg Phe Ser Ile Leu Gln Gln Gly Ser Pro Glu Leu Phe Ser Ile 
    130                 135                 140                 


Asp Glu Leu Thr Gly Glu Ile Arg Thr Val Gln Val Gly Leu Asp Arg 
145                 150                 155                 160 


Glu Val Val Ala Val Tyr Asn Leu Thr Leu Gln Val Ala Asp Met Ser 
                165                 170                 175     


Gly Asp Gly Leu Thr Ala Thr Ala Ser Ala Ile Ile Thr Leu Asp Asp 
            180                 185                 190         


Ile Asn Asp Asn Ala Pro Glu Phe Thr Arg Asp Glu Phe Phe Met Glu 
        195                 200                 205             


Ala Ile Glu Ala Val Ser Gly Val Asp Val Gly Arg Leu Glu Val Glu 
    210                 215                 220                 


Asp Arg Asp Leu Pro Gly Ser Pro Asn Trp Val Ala Arg Phe Thr Ile 
225                 230                 235                 240 


Leu Glu Gly Asp Pro Asp Gly Gln Phe Thr Ile Arg Thr Asp Pro Lys 
                245                 250                 255     


Thr Asn Glu Gly Val Leu Ser Ile Val Lys Ala Leu Asp Tyr Glu Ser 
            260                 265                 270         


Cys Glu His Tyr Glu Leu Lys Val Ser Val Gln Asn Glu Ala Pro Leu 
        275                 280                 285             


Gln Ala Ala Ala Leu Arg Ala Glu Arg Gly Gln Ala Lys Val Arg Val 
    290                 295                 300                 


His Val Gln Asp Thr Asn Glu Pro Pro Val Phe Gln Glu Asn Pro Leu 
305                 310                 315                 320 


Arg Thr Ser Leu Ala Glu Gly Ala Pro Pro Gly Thr Leu Val Ala Thr 
                325                 330                 335     


Phe Ser Ala Arg Asp Pro Asp Thr Glu Gln Leu Gln Arg Leu Ser Tyr 
            340                 345                 350         


Ser Lys Asp Tyr Asp Pro Glu Asp Trp Leu Gln Val Asp Ala Ala Thr 
        355                 360                 365             


Gly Arg Ile Gln Thr Gln His Val Leu Ser Pro Ala Ser Pro Phe Leu 
    370                 375                 380                 


Lys Gly Gly Trp Tyr Arg Ala Ile Val Leu Ala Gln Asp Asp Ala Ser 
385                 390                 395                 400 


Gln Pro Arg Thr Ala Thr Gly Thr Leu Ser Ile Glu Ile Leu Glu Val 
                405                 410                 415     


Asn Asp His Ala Pro Val Leu Ala Pro Pro Pro Pro Gly Ser Leu Cys 
            420                 425                 430         


Ser Glu Pro His Gln Gly Pro Gly Leu Leu Leu Gly Ala Thr Asp Glu 
        435                 440                 445             


Asp Leu Pro Pro His Gly Ala Pro Phe His Phe Gln Leu Ser Pro Arg 
    450                 455                 460                 


Leu Pro Glu Leu Gly Arg Asn Trp Ser Leu Ser Gln Val Asn Val Ser 
465                 470                 475                 480 


His Ala Arg Leu Arg Pro Arg His Gln Val Pro Glu Gly Leu His Arg 
                485                 490                 495     


Leu Ser Leu Leu Leu Arg Asp Ser Gly Gln Pro Pro Gln Gln Arg Glu 
            500                 505                 510         


Gln Pro Leu Asn Val Thr Val Cys Arg Cys Gly Lys Asp Gly Val Cys 
        515                 520                 525             


Leu Pro Gly Ala Ala Ala Leu Leu Ala Gly Gly Thr Gly Leu Ser Leu 
    530                 535                 540                 


Gly Ala 
545     


<210>  223
<211>  768
<212>  PRT
<213>  Homo Sapiens

<400>  223

Lys Ala Gln Pro Ala Glu Leu Ser Val Glu Val Pro Glu Asn Tyr Gly 
1               5                   10                  15      


Gly Asn Phe Pro Leu Tyr Leu Thr Lys Leu Pro Leu Pro Arg Glu Gly 
            20                  25                  30          


Ala Glu Gly Gln Ile Val Leu Ser Gly Asp Ser Gly Lys Ala Thr Glu 
        35                  40                  45              


Gly Pro Phe Ala Met Asp Pro Asp Ser Gly Phe Leu Leu Val Thr Arg 
    50                  55                  60                  


Ala Leu Asp Arg Glu Glu Gln Ala Glu Tyr Gln Leu Gln Val Thr Leu 
65                  70                  75                  80  


Glu Met Gln Asp Gly His Val Leu Trp Gly Pro Gln Pro Val Leu Val 
                85                  90                  95      


His Val Lys Asp Glu Asn Asp Gln Val Pro His Phe Ser Gln Ala Ile 
            100                 105                 110         


Tyr Arg Ala Arg Leu Ser Arg Gly Thr Arg Pro Gly Ile Pro Phe Leu 
        115                 120                 125             


Phe Leu Glu Ala Ser Asp Arg Asp Glu Pro Gly Thr Ala Asn Ser Asp 
    130                 135                 140                 


Leu Arg Phe His Ile Leu Ser Gln Ala Pro Ala Gln Pro Ser Pro Asp 
145                 150                 155                 160 


Met Phe Gln Leu Glu Pro Arg Leu Gly Ala Leu Ala Leu Ser Pro Lys 
                165                 170                 175     


Gly Ser Thr Ser Leu Asp His Ala Leu Glu Arg Thr Tyr Gln Leu Leu 
            180                 185                 190         


Val Gln Val Lys Asp Met Gly Asp Gln Ala Ser Gly His Gln Ala Thr 
        195                 200                 205             


Ala Thr Val Glu Val Ser Ile Ile Glu Ser Thr Trp Val Ser Leu Glu 
    210                 215                 220                 


Pro Ile His Leu Ala Glu Asn Leu Lys Val Leu Tyr Pro His His Met 
225                 230                 235                 240 


Ala Gln Val His Trp Ser Gly Gly Asp Val His Tyr His Leu Glu Ser 
                245                 250                 255     


His Pro Pro Gly Pro Phe Glu Val Asn Ala Glu Gly Asn Leu Tyr Val 
            260                 265                 270         


Thr Arg Glu Leu Asp Arg Glu Ala Gln Ala Glu Tyr Leu Leu Gln Val 
        275                 280                 285             


Arg Ala Gln Asn Ser His Gly Glu Asp Tyr Ala Ala Pro Leu Glu Leu 
    290                 295                 300                 


His Val Leu Val Met Asp Glu Asn Asp Asn Val Pro Ile Cys Pro Pro 
305                 310                 315                 320 


Arg Asp Pro Thr Val Ser Ile Pro Glu Leu Ser Pro Pro Gly Thr Glu 
                325                 330                 335     


Val Thr Arg Leu Ser Ala Glu Asp Ala Asp Ala Pro Gly Ser Pro Asn 
            340                 345                 350         


Ser His Val Val Tyr Gln Leu Leu Ser Pro Glu Pro Glu Asp Gly Val 
        355                 360                 365             


Glu Gly Arg Ala Phe Gln Val Asp Pro Thr Ser Gly Ser Val Thr Leu 
    370                 375                 380                 


Gly Val Leu Pro Leu Arg Ala Gly Gln Asn Ile Leu Leu Leu Val Leu 
385                 390                 395                 400 


Ala Met Asp Leu Ala Gly Ala Glu Gly Gly Phe Ser Ser Thr Cys Glu 
                405                 410                 415     


Val Glu Val Ala Val Thr Asp Ile Asn Asp His Ala Pro Glu Phe Ile 
            420                 425                 430         


Thr Ser Gln Ile Gly Pro Ile Ser Leu Pro Glu Asp Val Glu Pro Gly 
        435                 440                 445             


Thr Leu Val Ala Met Leu Thr Ala Ile Asp Ala Asp Leu Glu Pro Ala 
    450                 455                 460                 


Phe Arg Leu Met Asp Phe Ala Ile Glu Arg Gly Asp Thr Glu Gly Thr 
465                 470                 475                 480 


Phe Gly Leu Asp Trp Glu Pro Asp Ser Gly His Val Arg Leu Arg Leu 
                485                 490                 495     


Cys Lys Asn Leu Ser Tyr Glu Ala Ala Pro Ser His Glu Val Val Val 
            500                 505                 510         


Val Val Gln Ser Val Ala Lys Leu Val Gly Pro Gly Pro Gly Pro Gly 
        515                 520                 525             


Ala Thr Ala Thr Val Thr Val Leu Val Glu Arg Val Met Pro Pro Pro 
    530                 535                 540                 


Lys Leu Asp Gln Glu Ser Tyr Glu Ala Ser Val Pro Ile Ser Ala Pro 
545                 550                 555                 560 


Ala Gly Ser Phe Leu Leu Thr Ile Gln Pro Ser Asp Pro Ile Ser Arg 
                565                 570                 575     


Thr Leu Arg Phe Ser Leu Val Asn Asp Ser Glu Gly Trp Leu Cys Ile 
            580                 585                 590         


Glu Lys Phe Ser Gly Glu Val His Thr Ala Gln Ser Leu Gln Gly Ala 
        595                 600                 605             


Gln Pro Gly Asp Thr Tyr Thr Val Leu Val Glu Ala Gln Asp Thr Asp 
    610                 615                 620                 


Glu Pro Arg Leu Ser Ala Ser Ala Pro Leu Val Ile His Phe Leu Lys 
625                 630                 635                 640 


Ala Pro Pro Ala Pro Ala Leu Thr Leu Ala Pro Val Pro Ser Gln Tyr 
                645                 650                 655     


Leu Cys Thr Pro Arg Gln Asp His Gly Leu Ile Val Ser Gly Pro Ser 
            660                 665                 670         


Lys Asp Pro Asp Leu Ala Ser Gly His Gly Pro Tyr Ser Phe Thr Leu 
        675                 680                 685             


Gly Pro Asn Pro Thr Val Gln Arg Asp Trp Arg Leu Gln Thr Leu Asn 
    690                 695                 700                 


Gly Ser His Ala Tyr Leu Thr Leu Ala Leu His Trp Val Glu Pro Arg 
705                 710                 715                 720 


Glu His Ile Ile Pro Val Val Val Ser His Asn Ala Gln Met Trp Gln 
                725                 730                 735     


Leu Leu Val Arg Val Ile Val Cys Arg Cys Asn Val Glu Gly Gln Cys 
            740                 745                 750         


Met Arg Lys Val Gly Arg Met Lys Gly Met Pro Thr Lys Leu Ser Ala 
        755                 760                 765             


<210>  224
<211>  765
<212>  PRT
<213>  Homo Sapiens

<400>  224

Gln Glu Gly Lys Phe Ser Gly Pro Leu Lys Pro Met Thr Phe Ser Ile 
1               5                   10                  15      


Tyr Glu Gly Gln Glu Pro Ser Gln Ile Ile Phe Gln Phe Lys Ala Asn 
            20                  25                  30          


Pro Pro Ala Val Thr Phe Glu Leu Thr Gly Glu Thr Asp Asn Ile Phe 
        35                  40                  45              


Val Ile Glu Arg Glu Gly Leu Leu Tyr Tyr Asn Arg Ala Leu Asp Arg 
    50                  55                  60                  


Glu Thr Arg Ser Thr His Asn Leu Gln Val Ala Ala Leu Asp Ala Asn 
65                  70                  75                  80  


Gly Ile Ile Val Glu Gly Pro Val Pro Ile Thr Ile Glu Val Lys Asp 
                85                  90                  95      


Ile Asn Asp Asn Arg Pro Thr Phe Leu Gln Ser Lys Tyr Glu Gly Ser 
            100                 105                 110         


Val Arg Gln Asn Ser Arg Pro Gly Lys Pro Phe Leu Tyr Val Asn Ala 
        115                 120                 125             


Thr Asp Leu Asp Asp Pro Ala Thr Pro Asn Gly Gln Leu Tyr Tyr Gln 
    130                 135                 140                 


Ile Val Ile Gln Leu Pro Met Ile Asn Asn Val Met Tyr Phe Gln Ile 
145                 150                 155                 160 


Asn Asn Lys Thr Gly Ala Ile Ser Leu Thr Arg Glu Gly Ser Gln Glu 
                165                 170                 175     


Leu Asn Pro Ala Lys Asn Pro Ser Tyr Asn Leu Val Ile Ser Val Lys 
            180                 185                 190         


Asp Met Gly Gly Gln Ser Glu Asn Ser Phe Ser Asp Thr Thr Ser Val 
        195                 200                 205             


Asp Ile Ile Val Thr Glu Asn Ile Trp Lys Ala Pro Lys Pro Val Glu 
    210                 215                 220                 


Met Val Glu Asn Ser Thr Asp Pro His Pro Ile Lys Ile Thr Gln Val 
225                 230                 235                 240 


Arg Trp Asn Asp Pro Gly Ala Gln Tyr Ser Leu Val Asp Lys Glu Lys 
                245                 250                 255     


Leu Pro Arg Phe Pro Phe Ser Ile Asp Gln Glu Gly Asp Ile Tyr Val 
            260                 265                 270         


Thr Gln Pro Leu Asp Arg Glu Glu Lys Asp Ala Tyr Val Phe Tyr Ala 
        275                 280                 285             


Val Ala Lys Asp Glu Tyr Gly Lys Pro Leu Ser Tyr Pro Leu Glu Ile 
    290                 295                 300                 


His Val Lys Val Lys Asp Ile Asn Asp Asn Pro Pro Thr Cys Pro Ser 
305                 310                 315                 320 


Pro Val Thr Val Phe Glu Val Gln Glu Asn Glu Arg Leu Gly Asn Ser 
                325                 330                 335     


Ile Gly Thr Leu Thr Ala His Asp Arg Asp Glu Glu Asn Thr Ala Asn 
            340                 345                 350         


Ser Phe Leu Asn Tyr Arg Ile Val Glu Gln Thr Pro Lys Leu Pro Met 
        355                 360                 365             


Asp Gly Leu Phe Leu Ile Gln Thr Tyr Ala Gly Met Leu Gln Leu Ala 
    370                 375                 380                 


Lys Gln Ser Leu Lys Lys Gln Asp Thr Pro Gln Tyr Asn Leu Thr Ile 
385                 390                 395                 400 


Glu Val Ser Asp Lys Asp Phe Lys Thr Leu Cys Phe Val Gln Ile Asn 
                405                 410                 415     


Val Ile Asp Ile Asn Asp Gln Ile Pro Ile Phe Glu Lys Ser Asp Tyr 
            420                 425                 430         


Gly Asn Leu Thr Leu Ala Glu Asp Thr Asn Ile Gly Ser Thr Ile Leu 
        435                 440                 445             


Thr Ile Gln Ala Thr Asp Ala Asp Glu Pro Phe Thr Gly Ser Ser Lys 
    450                 455                 460                 


Ile Leu Tyr His Ile Ile Lys Gly Asp Ser Glu Gly Arg Leu Gly Val 
465                 470                 475                 480 


Asp Thr Asp Pro His Thr Asn Thr Gly Tyr Val Ile Ile Lys Lys Pro 
                485                 490                 495     


Leu Asp Phe Glu Thr Ala Ala Val Ser Asn Ile Val Phe Lys Ala Glu 
            500                 505                 510         


Asn Pro Glu Pro Leu Val Phe Gly Val Lys Tyr Asn Ala Ser Ser Phe 
        515                 520                 525             


Ala Lys Phe Thr Leu Ile Val Thr Asp Val Asn Glu Ala Pro Gln Phe 
    530                 535                 540                 


Ser Gln His Val Phe Gln Ala Lys Val Ser Glu Asp Val Ala Ile Gly 
545                 550                 555                 560 


Thr Lys Val Gly Asn Val Thr Ala Lys Asp Pro Glu Gly Leu Asp Ile 
                565                 570                 575     


Ser Tyr Ser Leu Arg Gly Asp Thr Arg Gly Trp Leu Lys Ile Asp His 
            580                 585                 590         


Val Thr Gly Glu Ile Phe Ser Val Ala Pro Leu Asp Arg Glu Ala Gly 
        595                 600                 605             


Ser Pro Tyr Arg Val Gln Val Val Ala Thr Glu Val Gly Gly Ser Ser 
    610                 615                 620                 


Leu Ser Ser Val Ser Glu Phe His Leu Ile Leu Met Asp Val Asn Asp 
625                 630                 635                 640 


Asn Pro Pro Arg Leu Ala Lys Asp Tyr Thr Gly Leu Phe Phe Cys His 
                645                 650                 655     


Pro Leu Ser Ala Pro Gly Ser Leu Ile Phe Glu Ala Thr Asp Asp Asp 
            660                 665                 670         


Gln His Leu Phe Arg Gly Pro His Phe Thr Phe Ser Leu Gly Ser Gly 
        675                 680                 685             


Ser Leu Gln Asn Asp Trp Glu Val Ser Lys Ile Asn Gly Thr His Ala 
    690                 695                 700                 


Arg Leu Ser Thr Arg His Thr Asp Phe Glu Glu Arg Glu Tyr Val Val 
705                 710                 715                 720 


Leu Ile Arg Ile Asn Asp Gly Gly Arg Pro Pro Leu Glu Gly Ile Val 
                725                 730                 735     


Ser Leu Pro Val Thr Phe Cys Ser Cys Val Glu Gly Ser Cys Phe Arg 
            740                 745                 750         


Pro Ala Gly His Gln Thr Gly Ile Pro Thr Val Gly Met 
        755                 760                 765 


<210>  225
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  225

Gly Trp Val Trp Asn Gln Phe Phe Val Leu Glu Glu His Met Gly Pro 
1               5                   10                  15      


Asp Pro Gln Tyr Val Gly Lys Leu His Ser Asn Ser Asp Lys Gly Asp 
            20                  25                  30          


Gly Ser Val Lys Tyr Ile Leu Thr Gly Glu Gly Ala Gly Thr Ile Phe 
        35                  40                  45              


Ile Ile Asp Asp Thr Thr Gly Asp Ile His Ser Thr Lys Ser Leu Asp 
    50                  55                  60                  


Arg Glu Gln Lys Thr His Tyr Val Leu His Ala Gln Ala Ile Asp Arg 
65                  70                  75                  80  


Arg Thr Asn Lys Pro Leu Glu Pro Glu Ser Glu Phe Ile Ile Lys Val 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Ala Pro Lys Phe Thr Asp Gly Pro Tyr Ile 
            100                 105                 110         


Val Thr Val Pro Glu Met Ser Asp Met Gly Thr Ser Val Leu Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Arg Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Asp Pro Lys 
145                 150                 155                 160 


Thr Gly Val Ile Arg Thr Ala Leu His Asn Met Asp Gly Glu Ala Arg 
                165                 170                 175     


Glu His Tyr Ser Val Val Ile Gln Ala Lys Asp Met Ala Gly Gln Val 
            180                 185                 190         


Gly Gly Leu Ser Gly Ser Thr Thr Val Asn Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Thr Pro Arg Phe Pro Gln Lys His Tyr Gln Leu Tyr Val 
    210                 215                 220                 


Pro Glu Ser Ala Gln Val Gly Ser Ala Val Gly Lys Ile Lys Ala Asn 
225                 230                 235                 240 


Asp Ala Asp Thr Gly Ser Asn Ala Asp Met Thr Tyr Ser Ile Ile Asn 
                245                 250                 255     


Gly Asp Gly Met Gly Ile Phe Ser Ile Ser Thr Asp Lys Glu Thr Arg 
            260                 265                 270         


Glu Gly Ile Leu Ser Leu Lys Lys Pro Leu Asn Tyr Glu Lys Lys Lys 
        275                 280                 285             


Ser Tyr Thr Leu Asn Ile Glu Gly Ala Asn Thr His Leu Asp Phe Arg 
    290                 295                 300                 


Phe Ser His Leu Gly Pro Phe Lys Asp Ala Thr Met Leu Lys Ile Ile 
305                 310                 315                 320 


Val Gly Asp Val Asp Glu Pro Pro Leu Phe Ser Met Pro Ser Tyr Leu 
                325                 330                 335     


Met Glu Val Tyr Glu Asn Ala Lys Ile Gly Thr Val Val Gly Thr Val 
            340                 345                 350         


Leu Ala Gln Asp Pro Asp Ser Ile Asn Ser Leu Val Arg Tyr Phe Ile 
        355                 360                 365             


Asn Tyr Asn Val Glu Asp Asp Arg Phe Phe Asn Ile Asp Ala Asn Thr 
    370                 375                 380                 


Gly Thr Ile Arg Thr Thr Lys Val Leu Asp Arg Glu Glu Thr Pro Trp 
385                 390                 395                 400 


Tyr Asn Ile Thr Val Thr Ala Ser Glu Ile Asp Asn Pro Asp Leu Leu 
                405                 410                 415     


Ser His Val Thr Val Gly Ile Arg Val Leu Asp Val Asn Asp Asn Pro 
            420                 425                 430         


Pro Glu Leu Ala Arg Glu Tyr Asp Ile Ile Val Cys Glu Asn Ser Lys 
        435                 440                 445             


Pro Gly Gln Val Ile His Thr Ile Ser Ala Thr Asp Lys Asp Asp Phe 
    450                 455                 460                 


Ala Asn Gly Pro Arg Phe Asn Phe Phe Leu Asp Glu Arg Leu Pro Val 
465                 470                 475                 480 


Asn Pro Asn Phe Thr Leu Lys Asp Asn Glu Asp Asn Thr Ala Ser Ile 
                485                 490                 495     


Leu Thr Arg Arg Arg Arg Phe Ser Arg Thr Val Gln Asp Val Tyr Tyr 
            500                 505                 510         


Leu Pro Ile Met Ile Ser Asp Gly Gly Ile Pro Ser Leu Ser Ser Ser 
        515                 520                 525             


Ser Thr Leu Thr Ile Arg Val Cys Ala Cys Glu Arg Asp Gly Arg Val 
    530                 535                 540                 


Arg Thr Cys His Ala Glu Ala Phe Leu Ser Ser 
545                 550                 555 


<210>  226
<211>  327
<212>  PRT
<213>  Homo Sapiens

<400>  226

Gly Trp Val Trp Asn Gln Phe Phe Val Pro Glu Glu Met Asn Thr Thr 
1               5                   10                  15      


Ser His His Ile Gly Gln Leu Arg Ser Asp Leu Asp Asn Gly Asn Asn 
            20                  25                  30          


Ser Phe Gln Tyr Lys Leu Leu Gly Ala Gly Ala Gly Ser Thr Phe Ile 
        35                  40                  45              


Ile Asp Glu Arg Thr Gly Asp Ile Tyr Ala Ile Gln Lys Leu Asp Arg 
    50                  55                  60                  


Glu Glu Arg Ser Leu Tyr Ile Leu Arg Ala Gln Val Ile Asp Ile Ala 
65                  70                  75                  80  


Thr Gly Arg Ala Val Glu Pro Glu Ser Glu Phe Val Ile Lys Val Ser 
                85                  90                  95      


Asp Ile Asn Asp Asn Glu Pro Lys Phe Leu Asp Glu Pro Tyr Glu Ala 
            100                 105                 110         


Ile Val Pro Glu Met Ser Pro Glu Gly Thr Leu Val Ile Gln Val Thr 
        115                 120                 125             


Ala Ser Asp Ala Asp Asp Pro Ser Ser Gly Asn Asn Ala Arg Leu Leu 
    130                 135                 140                 


Tyr Ser Leu Leu Gln Gly Gln Pro Tyr Phe Ser Val Glu Pro Thr Thr 
145                 150                 155                 160 


Gly Val Ile Arg Ile Ser Ser Lys Met Asp Arg Glu Leu Gln Asp Glu 
                165                 170                 175     


Tyr Trp Val Ile Ile Gln Ala Lys Asp Met Ile Gly Gln Pro Gly Ala 
            180                 185                 190         


Leu Ser Gly Thr Thr Ser Val Leu Ile Lys Leu Ser Asp Val Asn Asp 
        195                 200                 205             


Asn Lys Pro Ile Phe Lys Glu Ser Leu Tyr Arg Leu Thr Val Ser Glu 
    210                 215                 220                 


Ser Ala Pro Thr Gly Thr Ser Ile Gly Thr Ile Met Ala Tyr Asp Asn 
225                 230                 235                 240 


Asp Ile Gly Glu Asn Ala Glu Met Asp Tyr Ser Ile Glu Glu Asp Asp 
                245                 250                 255     


Ser Gln Thr Phe Asp Ile Ile Thr Asn His Glu Thr Gln Glu Gly Ile 
            260                 265                 270         


Val Ile Leu Lys Lys Lys Val Asp Phe Glu His Gln Asn His Tyr Gly 
        275                 280                 285             


Ile Arg Ala Lys Val Lys Asn His His Val Pro Glu Gln Leu Met Lys 
    290                 295                 300                 


Tyr His Thr Glu Ala Ser Thr Thr Phe Ile Lys Ile Gln Val Glu Asp 
305                 310                 315                 320 


Val Asp Glu Pro Pro Leu Phe 
                325         


<210>  227
<211>  565
<212>  PRT
<213>  Homo Sapiens

<400>  227

Asp Trp Val Ile Ser Pro Ile Asn Leu Pro Glu Asn Ser Arg Gly Pro 
1               5                   10                  15      


Phe Pro Gln Glu Leu Val Arg Ile Arg Ser Asp Arg Asp Lys Asn Leu 
            20                  25                  30          


Ser Leu Arg Tyr Ser Val Thr Gly Pro Gly Ala Asp Gln Pro Pro Thr 
        35                  40                  45              


Gly Ile Phe Ile Ile Asn Pro Ile Ser Gly Gln Leu Ser Val Thr Lys 
    50                  55                  60                  


Pro Leu Asp Arg Glu Gln Ile Ala Arg Phe His Leu Arg Ala His Ala 
65                  70                  75                  80  


Val Asp Ile Asn Gly Asn Gln Val Glu Asn Pro Ile Asp Ile Val Ile 
                85                  90                  95      


Asn Val Ile Asp Met Asn Asp Asn Arg Pro Glu Phe Leu His Gln Val 
            100                 105                 110         


Trp Asn Gly Thr Val Pro Glu Gly Ser Lys Pro Gly Thr Tyr Val Met 
        115                 120                 125             


Thr Val Thr Ala Ile Asp Ala Asp Asp Pro Asn Ala Leu Asn Gly Met 
    130                 135                 140                 


Leu Arg Tyr Arg Ile Val Ser Gln Ala Pro Ser Thr Pro Ser Pro Asn 
145                 150                 155                 160 


Met Phe Thr Ile Asn Asn Glu Thr Gly Asp Ile Ile Thr Val Ala Ala 
                165                 170                 175     


Gly Leu Asp Arg Glu Lys Val Gln Gln Tyr Thr Leu Ile Ile Gln Ala 
            180                 185                 190         


Thr Asp Met Glu Gly Asn Pro Thr Tyr Gly Leu Ser Asn Thr Ala Thr 
        195                 200                 205             


Ala Val Ile Thr Val Thr Asp Val Asn Asp Asn Pro Pro Glu Phe Thr 
    210                 215                 220                 


Ala Met Thr Phe Tyr Gly Glu Val Pro Glu Asn Arg Val Asp Ile Ile 
225                 230                 235                 240 


Val Ala Asn Leu Thr Val Thr Asp Lys Asp Gln Pro His Thr Pro Ala 
                245                 250                 255     


Trp Asn Ala Val Tyr Arg Ile Ser Gly Gly Asp Pro Thr Gly Arg Phe 
            260                 265                 270         


Ala Ile Gln Thr Asp Gln Asn Ser Asn Asp Gly Leu Val Thr Val Val 
        275                 280                 285             


Lys Pro Ile Asp Phe Glu Ala Asn Arg Met Phe Val Leu Thr Val Ala 
    290                 295                 300                 


Ala Glu Asn Gln Val Pro Leu Ala Lys Gly Ile Gln His Pro Pro Gln 
305                 310                 315                 320 


Ser Thr Ala Thr Met Ser Val Thr Val Ile Asp Val Asn Glu Asn Pro 
                325                 330                 335     


Tyr Phe Ala Pro Asn Pro Lys Ile Ile Arg Gln Glu Glu Gly Leu His 
            340                 345                 350         


Ala Gly Thr Met Leu Thr Thr Phe Thr Ala Gln Asp Pro Asp Arg Tyr 
        355                 360                 365             


Met Gln Gln Asn Ile Arg Tyr Thr Lys Leu Ser Asp Pro Ala Asn Trp 
    370                 375                 380                 


Leu Lys Ile Asp Pro Val Asn Gly Gln Ile Thr Thr Ile Ala Val Leu 
385                 390                 395                 400 


Asp Arg Glu Ser Pro Asn Val Lys Asn Asn Ile Tyr Asn Ala Thr Phe 
                405                 410                 415     


Leu Ala Ser Asp Asn Gly Ile Pro Pro Met Ser Gly Thr Gly Thr Leu 
            420                 425                 430         


Gln Ile Tyr Leu Leu Asp Ile Asn Asp Asn Ala Pro Gln Val Leu Pro 
        435                 440                 445             


Gln Glu Ala Glu Thr Cys Glu Thr Pro Asp Pro Asn Ser Ile Asn Ile 
    450                 455                 460                 


Thr Ala Leu Asp Tyr Gly Ile Asp Pro Asn Ala Gly Pro Phe Ala Phe 
465                 470                 475                 480 


Asp Leu Pro Leu Ser Pro Val Thr Ile Lys Arg Asn Trp Thr Ile Thr 
                485                 490                 495     


Arg Leu Asn Gly Asp Phe Ala Gln Leu Asn Leu Lys Ile Lys Phe Leu 
            500                 505                 510         


Glu Ala Gly Ile Tyr Glu Val Pro Ile Ile Ile Thr Asp Ser Gly Asn 
        515                 520                 525             


Pro Pro Lys Ser Asn Ile Ser Ile Leu Arg Val Lys Val Cys Gln Cys 
    530                 535                 540                 


Asp Ser Asn Gly Asp Cys Thr Asp Val Asp Arg Ile Val Gly Ala Gly 
545                 550                 555                 560 


Leu Gly Thr Gly Ala 
                565 


<210>  228
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  228

Ser Trp Val Trp Asn Gln Phe Phe Val Leu Glu Glu Tyr Thr Gly Thr 
1               5                   10                  15      


Asp Pro Leu Tyr Val Gly Lys Leu His Ser Asp Met Asp Arg Gly Asp 
            20                  25                  30          


Gly Ser Ile Lys Tyr Ile Leu Ser Gly Glu Gly Ala Gly Ile Val Phe 
        35                  40                  45              


Thr Ile Asp Asp Thr Thr Gly Asp Ile His Ala Ile Gln Arg Leu Asp 
    50                  55                  60                  


Arg Glu Glu Arg Ala Gln Tyr Thr Leu Arg Ala Gln Ala Leu Asp Arg 
65                  70                  75                  80  


Arg Thr Gly Arg Pro Met Glu Pro Glu Ser Glu Phe Ile Ile Lys Ile 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Glu Pro Lys Phe Leu Asp Gly Pro Tyr Val 
            100                 105                 110         


Ala Thr Val Pro Glu Met Ser Pro Val Gly Thr Ser Val Ile Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Arg Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Asp Ser Lys 
145                 150                 155                 160 


Thr Gly Val Ile Arg Thr Ala Leu Met Asn Met Asp Arg Glu Ala Lys 
                165                 170                 175     


Glu Tyr Tyr Glu Val Ile Ile Gln Ala Lys Asp Met Gly Gly Gln Leu 
            180                 185                 190         


Gly Gly Leu Ala Gly Thr Thr Thr Val Asn Ile Thr Leu Ser Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Arg Phe Pro Gln Lys His Tyr Gln Met Ser Val 
    210                 215                 220                 


Leu Glu Ser Ala Pro Ile Ser Ser Thr Val Gly Arg Val Phe Ala Lys 
225                 230                 235                 240 


Asp Leu Asp Glu Gly Ile Asn Ala Glu Met Lys Tyr Thr Ile Val Asp 
                245                 250                 255     


Gly Asp Gly Ala Asp Ala Phe Asp Ile Ser Thr Asp Pro Asn Phe Gln 
            260                 265                 270         


Val Gly Ile Ile Thr Val Lys Lys Pro Leu Ser Phe Glu Ser Lys Lys 
        275                 280                 285             


Ser Tyr Thr Leu Lys Val Glu Gly Ala Asn Pro His Leu Glu Met Arg 
    290                 295                 300                 


Phe Leu Asn Leu Gly Pro Phe Gln Asp Thr Thr Thr Val His Ile Ser 
305                 310                 315                 320 


Val Glu Asp Val Asp Glu Pro Pro Val Phe Glu Pro Gly Phe Tyr Phe 
                325                 330                 335     


Val Glu Val Pro Glu Asp Val Ala Ile Gly Thr Thr Ile Gln Ile Ile 
            340                 345                 350         


Ser Ala Lys Asp Pro Asp Val Thr Asn Asn Ser Ile Arg Tyr Ser Ile 
        355                 360                 365             


Asp Arg Ser Ser Asp Pro Gly Arg Phe Phe Tyr Val Asp Ile Thr Thr 
    370                 375                 380                 


Gly Ala Leu Met Thr Ala Arg Pro Leu Asp Arg Glu Glu Phe Ser Trp 
385                 390                 395                 400 


His Asn Ile Thr Val Leu Ala Met Glu Met Asn Asn Pro Ser Gln Val 
                405                 410                 415     


Gly Ser Val Pro Val Thr Ile Lys Val Leu Asp Val Asn Asp Asn Ala 
            420                 425                 430         


Pro Glu Phe Pro Arg Phe Tyr Glu Ala Phe Val Cys Glu Asn Ala Lys 
        435                 440                 445             


Ala Gly Gln Leu Ile Gln Thr Val Ser Ala Val Asp Gln Asp Asp Pro 
    450                 455                 460                 


Arg Asn Gly Gln His Phe Tyr Tyr Ser Leu Ala Pro Glu Ala Ala Asn 
465                 470                 475                 480 


Asn Pro Asn Phe Thr Ile Arg Asp Asn Gln Asp Asn Thr Ala Arg Ile 
                485                 490                 495     


Leu Thr Arg Arg Ser Gly Phe Arg Gln Gln Glu Gln Ser Val Phe His 
            500                 505                 510         


Leu Pro Ile Leu Ile Ala Asp Ser Gly Gln Pro Val Leu Ser Ser Thr 
        515                 520                 525             


Gly Thr Leu Thr Ile Gln Val Cys Ser Cys Asp Asp Asp Gly His Val 
    530                 535                 540                 


Met Ser Cys Ser Pro Glu Ala Tyr Met Leu Pro Val Ser Leu Ser Arg 
545                 550                 555                 560 


<210>  229
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  229

Leu Ala Thr Pro Tyr Glu Ala Ala Val Cys Glu Asp Ala Lys Pro Gly 
1               5                   10                  15      


Gln Leu Ile Gln Thr Ile Ser Val Val Asp Arg Asp Glu Pro Gln Gly 
            20                  25                  30          


Gly His Arg Phe Tyr Phe Arg Leu Val Pro Glu Ala Pro Ser Asn Pro 
        35                  40                  45              


His Phe Ser Leu Leu Asp Ile Gln Asp Asn Thr Ala Ala Val His Thr 
    50                  55                  60                  


Gln His Val Gly Phe Asn Arg Gln Glu Gln Asp Val Phe Phe Leu Pro 
65                  70                  75                  80  


Ile Leu Val Val Asp Ser Gly Pro Pro Thr Leu Ser Ser Thr Gly Thr 
                85                  90                  95      


Leu Thr Ile Arg Ile Cys Gly Cys Asp Ser Ser Gly Thr Ile Gln Ser 
            100                 105                 110         


Cys Asn Thr Thr Ala Phe Val Met Ala Ala Ser Leu Ser Pro 
        115                 120                 125     


<210>  230
<211>  972
<212>  PRT
<213>  Homo Sapiens

<400>  230

Gln Val Asn Arg Leu Pro Phe Phe Thr Asn His Phe Phe Asp Thr Tyr 
1               5                   10                  15      


Leu Leu Ile Ser Glu Asp Thr Pro Val Gly Ser Ser Val Thr Gln Leu 
            20                  25                  30          


Leu Ala Gln Asp Met Asp Asn Asp Pro Leu Val Phe Gly Val Ser Gly 
        35                  40                  45              


Glu Glu Ala Ser Arg Phe Phe Ala Val Glu Pro Asp Thr Gly Val Val 
    50                  55                  60                  


Trp Leu Arg Gln Pro Leu Asp Arg Glu Thr Lys Ser Glu Phe Thr Val 
65                  70                  75                  80  


Glu Phe Ser Val Ser Asp His Gln Gly Val Ile Thr Arg Lys Val Asn 
                85                  90                  95      


Ile Gln Val Gly Asp Val Asn Asp Asn Ala Pro Thr Phe His Asn Gln 
            100                 105                 110         


Pro Tyr Ser Val Arg Ile Pro Glu Asn Thr Pro Val Gly Thr Pro Ile 
        115                 120                 125             


Phe Ile Val Asn Ala Thr Asp Pro Asp Leu Gly Ala Gly Gly Ser Val 
    130                 135                 140                 


Leu Tyr Ser Phe Gln Pro Pro Ser Gln Phe Phe Ala Ile Asp Ser Ala 
145                 150                 155                 160 


Arg Gly Ile Val Thr Val Ile Arg Glu Leu Asp Tyr Glu Thr Thr Gln 
                165                 170                 175     


Ala Tyr Gln Leu Thr Val Asn Ala Thr Asp Gln Asp Lys Thr Arg Pro 
            180                 185                 190         


Leu Ser Thr Leu Ala Asn Leu Ala Ile Ile Ile Thr Asp Val Gln Asp 
        195                 200                 205             


Met Asp Pro Ile Phe Ile Asn Leu Pro Tyr Ser Thr Asn Ile Tyr Glu 
    210                 215                 220                 


His Ser Pro Pro Gly Thr Thr Val Arg Ile Ile Thr Ala Ile Asp Gln 
225                 230                 235                 240 


Asp Lys Gly Arg Pro Arg Gly Ile Gly Tyr Thr Ile Val Ser Gly Asn 
                245                 250                 255     


Thr Asn Ser Ile Phe Ala Leu Asp Tyr Ile Ser Gly Val Leu Thr Leu 
            260                 265                 270         


Asn Gly Leu Leu Asp Arg Glu Asn Pro Leu Tyr Ser His Gly Phe Ile 
        275                 280                 285             


Leu Thr Val Lys Gly Thr Glu Leu Asn Asp Asp Arg Thr Pro Ser Asp 
    290                 295                 300                 


Ala Thr Val Thr Thr Thr Phe Asn Ile Leu Val Ile Asp Ile Asn Asp 
305                 310                 315                 320 


Asn Ala Pro Glu Phe Asn Ser Ser Glu Tyr Ser Val Ala Ile Thr Glu 
                325                 330                 335     


Leu Ala Gln Val Gly Phe Ala Leu Pro Leu Phe Ile Gln Val Val Asp 
            340                 345                 350         


Lys Asp Glu Asn Leu Gly Leu Asn Ser Met Phe Glu Val Tyr Leu Val 
        355                 360                 365             


Gly Asn Asn Ser His His Phe Ile Ile Ser Pro Thr Ser Val Gln Gly 
    370                 375                 380                 


Lys Ala Asp Ile Arg Ile Arg Val Ala Ile Pro Leu Asp Tyr Glu Thr 
385                 390                 395                 400 


Val Asp Arg Tyr Asp Phe Asp Leu Phe Ala Asn Glu Ser Val Pro Asp 
                405                 410                 415     


His Val Gly Tyr Ala Lys Val Lys Ile Thr Leu Ile Asn Glu Asn Asp 
            420                 425                 430         


Asn Arg Pro Ile Phe Ser Gln Pro Leu Tyr Asn Ile Ser Leu Tyr Glu 
        435                 440                 445             


Asn Val Thr Val Gly Thr Ser Val Leu Thr Val Leu Ala Thr Asp Asn 
    450                 455                 460                 


Asp Ala Gly Thr Phe Gly Glu Val Ser Tyr Phe Phe Ser Asp Asp Pro 
465                 470                 475                 480 


Asp Arg Phe Ser Leu Asp Lys Asp Thr Gly Leu Ile Met Leu Ile Ala 
                485                 490                 495     


Arg Leu Asp Tyr Glu Leu Ile Gln Arg Phe Thr Leu Thr Ile Ile Ala 
            500                 505                 510         


Arg Asp Gly Gly Gly Glu Glu Thr Thr Gly Arg Val Arg Ile Asn Val 
        515                 520                 525             


Leu Asp Val Asn Asp Asn Val Pro Thr Phe Gln Lys Asp Ala Tyr Val 
    530                 535                 540                 


Gly Ala Leu Arg Glu Asn Glu Pro Ser Val Thr Gln Leu Val Arg Leu 
545                 550                 555                 560 


Arg Ala Thr Asp Glu Asp Ser Pro Pro Asn Asn Gln Ile Thr Tyr Ser 
                565                 570                 575     


Ile Val Ser Ala Ser Ala Phe Gly Ser Tyr Phe Asp Ile Ser Leu Tyr 
            580                 585                 590         


Glu Gly Tyr Gly Val Ile Ser Val Ser Arg Pro Leu Asp Tyr Glu Gln 
        595                 600                 605             


Ile Ser Asn Gly Leu Ile Tyr Leu Thr Val Met Ala Met Asp Ala Gly 
    610                 615                 620                 


Asn Pro Pro Leu Asn Ser Thr Val Pro Val Thr Ile Glu Val Phe Asp 
625                 630                 635                 640 


Glu Asn Asp Asn Pro Pro Thr Phe Ser Lys Pro Ala Tyr Phe Val Ser 
                645                 650                 655     


Val Val Glu Asn Ile Met Ala Gly Ala Thr Val Leu Phe Leu Asn Ala 
            660                 665                 670         


Thr Asp Leu Asp Arg Ser Arg Glu Tyr Gly Gln Glu Ser Ile Ile Tyr 
        675                 680                 685             


Ser Leu Glu Gly Ser Thr Gln Phe Arg Ile Asn Ala Arg Ser Gly Glu 
    690                 695                 700                 


Ile Thr Thr Thr Ser Leu Leu Asp Arg Glu Thr Lys Ser Glu Tyr Ile 
705                 710                 715                 720 


Leu Ile Val Arg Ala Val Asp Gly Gly Val Gly His Asn Gln Lys Thr 
                725                 730                 735     


Gly Ile Ala Thr Val Asn Ile Thr Leu Leu Asp Ile Asn Asp Asn His 
            740                 745                 750         


Pro Thr Trp Lys Asp Ala Pro Tyr Tyr Ile Asn Leu Val Glu Met Thr 
        755                 760                 765             


Pro Pro Asp Ser Asp Val Thr Thr Val Val Ala Val Asp Pro Asp Leu 
    770                 775                 780                 


Gly Glu Asn Gly Thr Leu Val Tyr Ser Ile Gln Pro Pro Asn Lys Phe 
785                 790                 795                 800 


Tyr Ser Leu Asn Ser Thr Thr Gly Lys Ile Arg Thr Thr His Ala Met 
                805                 810                 815     


Leu Asp Arg Glu Asn Pro Asp Pro His Glu Ala Glu Leu Met Arg Lys 
            820                 825                 830         


Ile Val Val Ser Val Thr Asp Cys Gly Arg Pro Pro Leu Lys Ala Thr 
        835                 840                 845             


Ser Ser Ala Thr Val Phe Val Asn Leu Leu Asp Leu Asn Asp Asn Asp 
    850                 855                 860                 


Pro Thr Phe Gln Asn Leu Pro Phe Val Ala Glu Val Leu Glu Gly Ile 
865                 870                 875                 880 


Pro Ala Gly Val Ser Ile Tyr Gln Val Val Ala Ile Asp Leu Asp Glu 
                885                 890                 895     


Gly Leu Asn Gly Leu Val Ser Tyr Arg Met Pro Val Gly Met Pro Arg 
            900                 905                 910         


Met Asp Phe Leu Ile Asn Ser Ser Ser Gly Val Val Val Thr Thr Thr 
        915                 920                 925             


Glu Leu Asp Arg Glu Arg Ile Ala Glu Tyr Gln Leu Arg Val Val Ala 
    930                 935                 940                 


Ser Asp Ala Gly Thr Pro Thr Lys Ser Ser Thr Ser Thr Leu Thr Ile 
945                 950                 955                 960 


His Val Leu Asp Val Asn Asp Glu Thr Pro Thr Phe 
                965                 970         


<210>  231
<211>  559
<212>  PRT
<213>  Homo Sapiens

<400>  231

Ser Trp Val Trp Asn Gln Phe Phe Val Ile Glu Glu Tyr Ala Gly Pro 
1               5                   10                  15      


Glu Pro Val Leu Ile Gly Lys Leu His Ser Asp Val Asp Arg Gly Glu 
            20                  25                  30          


Gly Arg Thr Lys Tyr Leu Leu Thr Gly Glu Gly Ala Gly Thr Val Phe 
        35                  40                  45              


Val Ile Asp Glu Ala Thr Gly Asn Ile His Val Thr Lys Ser Leu Asp 
    50                  55                  60                  


Arg Glu Glu Lys Ala Gln Tyr Val Leu Leu Ala Gln Ala Val Asp Arg 
65                  70                  75                  80  


Ala Ser Asn Arg Pro Leu Glu Pro Pro Ser Glu Phe Ile Ile Lys Val 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Pro Pro Ile Phe Pro Leu Gly Pro Tyr His 
            100                 105                 110         


Ala Thr Val Pro Glu Met Ser Asn Val Gly Thr Ser Val Ile Gln Val 
        115                 120                 125             


Thr Ala His Asp Ala Asp Asp Pro Ser Tyr Gly Asn Ser Ala Lys Leu 
    130                 135                 140                 


Val Tyr Thr Val Leu Asp Gly Leu Pro Phe Phe Ser Val Asp Pro Gln 
145                 150                 155                 160 


Thr Gly Val Val Arg Thr Ala Ile Pro Asn Met Asp Arg Glu Thr Gln 
                165                 170                 175     


Glu Glu Phe Leu Val Val Ile Gln Ala Lys Asp Met Gly Gly His Met 
            180                 185                 190         


Gly Gly Leu Ser Gly Ser Thr Thr Val Thr Val Thr Leu Ser Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Lys Phe Pro Gln Ser Leu Tyr Gln Phe Ser Val 
    210                 215                 220                 


Val Glu Thr Ala Gly Pro Gly Thr Leu Val Gly Arg Leu Arg Ala Gln 
225                 230                 235                 240 


Asp Pro Asp Leu Gly Asp Asn Ala Leu Met Ala Tyr Ser Ile Leu Asp 
                245                 250                 255     


Gly Glu Gly Ser Glu Ala Phe Ser Ile Ser Thr Asp Leu Gln Gly Arg 
            260                 265                 270         


Asp Gly Leu Leu Thr Val Arg Lys Pro Leu Asp Phe Glu Ser Gln Arg 
        275                 280                 285             


Ser Tyr Ser Phe Arg Val Glu Ala Thr Asn Thr Leu Ile Asp Pro Ala 
    290                 295                 300                 


Tyr Leu Arg Arg Gly Pro Phe Lys Asp Val Ala Ser Val Arg Val Ala 
305                 310                 315                 320 


Val Gln Asp Ala Pro Glu Pro Pro Ala Phe Thr Gln Ala Ala Tyr His 
                325                 330                 335     


Leu Thr Val Pro Glu Asn Lys Ala Pro Gly Thr Leu Val Gly Gln Ile 
            340                 345                 350         


Ser Ala Ala Asp Leu Asp Ser Pro Ala Ser Pro Ile Arg Tyr Ser Ile 
        355                 360                 365             


Leu Pro His Ser Asp Pro Glu Arg Cys Phe Ser Ile Gln Pro Glu Glu 
    370                 375                 380                 


Gly Thr Ile His Thr Ala Ala Pro Leu Asp Arg Glu Ala Arg Ala Trp 
385                 390                 395                 400 


His Asn Leu Thr Val Leu Ala Thr Glu Leu Asp Ser Ser Ala Gln Ala 
                405                 410                 415     


Ser Arg Val Gln Val Ala Ile Gln Thr Leu Asp Glu Asn Asp Asn Ala 
            420                 425                 430         


Pro Gln Leu Ala Glu Pro Tyr Asp Thr Phe Val Cys Asp Ser Ala Ala 
        435                 440                 445             


Pro Gly Gln Leu Ile Gln Val Ile Arg Ala Leu Asp Arg Asp Glu Val 
    450                 455                 460                 


Gly Asn Ser Ser His Val Ser Phe Gln Gly Pro Leu Gly Pro Asp Ala 
465                 470                 475                 480 


Asn Phe Thr Val Gln Asp Asn Arg Asp Gly Ser Ala Ser Leu Leu Leu 
                485                 490                 495     


Pro Ser Arg Pro Ala Pro Pro Arg His Ala Pro Tyr Leu Val Pro Ile 
            500                 505                 510         


Glu Leu Trp Asp Trp Gly Gln Pro Ala Leu Ser Ser Thr Ala Thr Val 
        515                 520                 525             


Thr Val Ser Val Cys Arg Cys Gln Pro Asp Gly Ser Val Ala Ser Cys 
    530                 535                 540                 


Trp Pro Glu Ala His Leu Ser Ala Ala Gly Leu Ser Thr Gly Ala 
545                 550                 555                 


<210>  232
<211>  594
<212>  PRT
<213>  Homo Sapiens

<400>  232

Ile Asp Ser Val Gln Gln Glu Thr Asp Asp Leu Thr Lys Gln Thr Lys 
1               5                   10                  15      


Cys His Tyr Lys Phe Gln Glu Lys Ile Tyr Gln Pro Leu Arg Arg Ser 
            20                  25                  30          


Lys Arg Arg Trp Val Ile Thr Thr Leu Glu Met Glu Glu Glu Asp Pro 
        35                  40                  45              


Gly Pro Phe Pro Lys Leu Ile Gly Glu Leu Phe Asn Asn Met Ser Tyr 
    50                  55                  60                  


Asn Met Ser Leu Met Tyr Leu Ile Ser Gly Pro Gly Val Asp Glu Tyr 
65                  70                  75                  80  


Pro Glu Ile Gly Leu Phe Ser Leu Glu Asp His Glu Asn Gly Arg Ile 
                85                  90                  95      


Tyr Val His Arg Pro Val Asp Arg Glu Met Thr Pro Ser Phe Thr Val 
            100                 105                 110         


Tyr Phe Asp Val Val Glu Arg Ser Thr Gly Lys Ile Val Asp Thr Ser 
        115                 120                 125             


Leu Ile Phe Asn Ile Arg Ile Ser Asp Val Asn Asp His Ala Pro Gln 
    130                 135                 140                 


Phe Pro Glu Lys Glu Phe Asn Ile Thr Val Gln Glu Asn Gln Ser Ala 
145                 150                 155                 160 


Gly Gln Pro Ile Phe Gln Met Leu Ala Val Asp Leu Asp Glu Glu Asn 
                165                 170                 175     


Thr Pro Asn Ser Gln Val Leu Tyr Phe Leu Ile Ser Gln Thr Pro Leu 
            180                 185                 190         


Leu Lys Glu Ser Gly Phe Arg Val Asp Arg Leu Ser Gly Glu Ile Arg 
        195                 200                 205             


Leu Ser Gly Cys Leu Asp Tyr Glu Thr Ala Pro Gln Phe Thr Leu Leu 
    210                 215                 220                 


Ile Arg Ala Arg Asp Cys Gly Glu Pro Ser Leu Ser Ser Thr Thr Thr 
225                 230                 235                 240 


Val His Val Asp Val Gln Glu Gly Asn Asn His Arg Pro Ala Phe Thr 
                245                 250                 255     


Gln Glu Asn Tyr Lys Val Gln Ile Pro Glu Gly Arg Ala Ser Gln Gly 
            260                 265                 270         


Val Leu Arg Leu Leu Val Gln Asp Arg Asp Ser Pro Phe Thr Ser Ala 
        275                 280                 285             


Trp Arg Ala Lys Phe Asn Ile Leu His Gly Asn Glu Glu Gly His Phe 
    290                 295                 300                 


Asp Ile Ser Thr Asp Pro Glu Thr Asn Glu Gly Ile Leu Asn Val Ile 
305                 310                 315                 320 


Lys Pro Leu Asp Tyr Glu Thr Arg Pro Ala Gln Ser Leu Ile Ile Val 
                325                 330                 335     


Val Glu Asn Glu Glu Arg Leu Val Phe Cys Glu Arg Gly Lys Leu Gln 
            340                 345                 350         


Pro Pro Arg Lys Ala Ala Ala Ser Ala Thr Val Ser Val Gln Val Thr 
        355                 360                 365             


Asp Ala Asn Asp Pro Pro Ala Phe His Pro Gln Ser Phe Ile Val Asn 
    370                 375                 380                 


Lys Glu Glu Gly Ala Arg Pro Gly Thr Leu Leu Gly Thr Phe Asn Ala 
385                 390                 395                 400 


Met Asp Pro Asp Ser Gln Ile Arg Tyr Glu Leu Val His Asp Pro Ala 
                405                 410                 415     


Asn Trp Val Ser Val Asp Lys Asn Ser Gly Val Val Ile Thr Val Glu 
            420                 425                 430         


Pro Ile Asp Arg Glu Ser Pro His Val Asn Asn Ser Phe Tyr Val Ile 
        435                 440                 445             


Ile Ile His Ala Val Asp Asp Gly Phe Pro Pro Gln Thr Ala Thr Gly 
    450                 455                 460                 


Thr Leu Met Leu Phe Leu Ser Asp Ile Asn Asp Asn Val Pro Thr Leu 
465                 470                 475                 480 


Arg Pro Arg Ser Arg Tyr Met Glu Val Cys Glu Ser Ala Val His Glu 
                485                 490                 495     


Pro Leu His Ile Glu Ala Glu Asp Pro Asp Leu Glu Pro Phe Ser Asp 
            500                 505                 510         


Pro Phe Thr Phe Glu Leu Asp Asn Thr Trp Gly Asn Ala Glu Asp Thr 
        515                 520                 525             


Trp Lys Leu Gly Arg Asn Trp Gly Gln Ser Val Glu Leu Leu Thr Leu 
    530                 535                 540                 


Arg Ser Leu Pro Arg Gly Asn Tyr Leu Val Pro Leu Phe Ile Gly Asp 
545                 550                 555                 560 


Lys Gln Gly Leu Ser Gln Lys Gln Thr Val His Val Arg Ile Cys Pro 
                565                 570                 575     


Cys Ala Ser Gly Leu Thr Cys Val Glu Leu Ala Asp Ala Glu Val Gly 
            580                 585                 590         


Leu His 
        


<210>  233
<211>  547
<212>  PRT
<213>  Homo Sapiens

<400>  233

Asp Trp Val Val Ala Pro Ile Ser Val Pro Glu Asn Gly Lys Gly Pro 
1               5                   10                  15      


Phe Pro Gln Arg Leu Asn Gln Leu Lys Ser Asn Lys Asp Arg Asp Thr 
            20                  25                  30          


Lys Ile Phe Tyr Ser Ile Thr Gly Pro Gly Ala Asp Ser Pro Pro Glu 
        35                  40                  45              


Gly Val Phe Ala Val Glu Lys Glu Thr Gly Trp Leu Leu Leu Asn Lys 
    50                  55                  60                  


Pro Leu Asp Arg Glu Glu Ile Ala Lys Tyr Glu Leu Phe Gly His Ala 
65                  70                  75                  80  


Val Ser Glu Asn Gly Ala Ser Val Glu Asp Pro Met Asn Ile Ser Ile 
                85                  90                  95      


Ile Val Thr Asp Gln Asn Asp His Lys Pro Lys Phe Thr Gln Asp Thr 
            100                 105                 110         


Phe Arg Gly Ser Val Leu Glu Gly Val Leu Pro Gly Thr Ser Val Met 
        115                 120                 125             


Gln Met Thr Ala Thr Asp Glu Asp Asp Ala Ile Tyr Thr Tyr Asn Gly 
    130                 135                 140                 


Val Val Ala Tyr Ser Ile His Ser Gln Glu Pro Lys Asp Pro His Asp 
145                 150                 155                 160 


Leu Met Phe Thr Ile His Arg Ser Thr Gly Thr Ile Ser Val Ile Ser 
                165                 170                 175     


Ser Gly Leu Asp Arg Glu Lys Val Pro Glu Tyr Thr Leu Thr Ile Gln 
            180                 185                 190         


Ala Thr Asp Met Asp Gly Asp Gly Ser Thr Thr Thr Ala Val Ala Val 
        195                 200                 205             


Val Glu Ile Leu Asp Ala Asn Asp Asn Ala Pro Met Phe Asp Pro Gln 
    210                 215                 220                 


Lys Tyr Glu Ala His Val Pro Glu Asn Ala Val Gly His Glu Val Gln 
225                 230                 235                 240 


Arg Leu Thr Val Thr Asp Leu Asp Ala Pro Asn Ser Pro Ala Trp Arg 
                245                 250                 255     


Ala Thr Tyr Leu Ile Met Gly Gly Asp Asp Gly Asp His Phe Thr Ile 
            260                 265                 270         


Thr Thr His Pro Glu Ser Asn Gln Gly Ile Leu Thr Thr Arg Lys Gly 
        275                 280                 285             


Leu Asp Phe Glu Ala Lys Asn Gln His Thr Leu Tyr Val Glu Val Thr 
    290                 295                 300                 


Asn Glu Ala Pro Phe Val Leu Lys Leu Pro Thr Ser Thr Ala Thr Ile 
305                 310                 315                 320 


Val Val His Val Glu Asp Val Asn Glu Ala Pro Val Phe Val Pro Pro 
                325                 330                 335     


Ser Lys Val Val Glu Val Gln Glu Gly Ile Pro Thr Gly Glu Pro Val 
            340                 345                 350         


Cys Val Tyr Thr Ala Glu Asp Pro Asp Lys Glu Asn Gln Lys Ile Ser 
        355                 360                 365             


Tyr Arg Ile Leu Arg Asp Pro Ala Gly Trp Leu Ala Met Asp Pro Asp 
    370                 375                 380                 


Ser Gly Gln Val Thr Ala Val Gly Thr Leu Asp Arg Glu Asp Glu Gln 
385                 390                 395                 400 


Phe Val Arg Asn Asn Ile Tyr Glu Val Met Val Leu Ala Met Asp Asn 
                405                 410                 415     


Gly Ser Pro Pro Thr Thr Gly Thr Gly Thr Leu Leu Leu Thr Leu Ile 
            420                 425                 430         


Asp Val Asn Asp His Gly Pro Val Pro Glu Pro Arg Gln Ile Thr Ile 
        435                 440                 445             


Cys Asn Gln Ser Pro Val Arg Gln Val Leu Asn Ile Thr Asp Lys Asp 
    450                 455                 460                 


Leu Ser Pro His Thr Ser Pro Phe Gln Ala Gln Leu Thr Asp Asp Ser 
465                 470                 475                 480 


Asp Ile Tyr Trp Thr Ala Glu Val Asn Glu Glu Gly Asp Thr Val Val 
                485                 490                 495     


Leu Ser Leu Lys Lys Phe Leu Lys Gln Asp Thr Tyr Asp Val His Leu 
            500                 505                 510         


Ser Leu Ser Asp His Gly Asn Lys Glu Gln Leu Thr Val Ile Arg Ala 
        515                 520                 525             


Thr Val Cys Asp Cys His Gly His Val Glu Thr Cys Pro Gly Pro Trp 
    530                 535                 540                 


Lys Gly Gly 
545         


<210>  234
<211>  565
<212>  PRT
<213>  Homo Sapiens

<400>  234

Asp Trp Val Ile Pro Pro Ile Asn Val Pro Glu Asn Ser Arg Gly Pro 
1               5                   10                  15      


Phe Pro Gln Gln Leu Val Arg Ile Arg Ser Asp Lys Asp Asn Asp Ile 
            20                  25                  30          


Pro Ile Arg Tyr Ser Ile Thr Gly Val Gly Ala Asp Gln Pro Pro Met 
        35                  40                  45              


Glu Val Phe Ser Ile Asp Ser Met Ser Gly Arg Met Tyr Val Thr Arg 
    50                  55                  60                  


Pro Met Asp Arg Glu Glu His Ala Ser Tyr His Leu Arg Ala His Ala 
65                  70                  75                  80  


Val Asp Met Asn Gly Asn Lys Val Glu Asn Pro Ile Asp Leu Tyr Ile 
                85                  90                  95      


Tyr Val Ile Asp Met Asn Asp Asn Arg Pro Glu Phe Ile Asn Gln Val 
            100                 105                 110         


Tyr Asn Gly Ser Val Asp Glu Gly Ser Lys Pro Gly Thr Tyr Val Met 
        115                 120                 125             


Thr Val Thr Ala Asn Asp Ala Asp Asp Ser Thr Thr Ala Asn Gly Met 
    130                 135                 140                 


Val Arg Tyr Arg Ile Val Thr Gln Thr Pro Gln Ser Pro Ser Gln Asn 
145                 150                 155                 160 


Met Phe Thr Ile Asn Ser Glu Thr Gly Asp Ile Val Thr Val Ala Ala 
                165                 170                 175     


Gly Leu Asp Arg Glu Lys Val Gln Gln Tyr Thr Val Ile Val Gln Ala 
            180                 185                 190         


Thr Asp Met Glu Gly Asn Leu Asn Tyr Gly Leu Ser Asn Thr Ala Thr 
        195                 200                 205             


Ala Ile Ile Thr Val Thr Asp Val Asn Asp Asn Pro Pro Glu Phe Thr 
    210                 215                 220                 


Ala Ser Thr Phe Ala Gly Glu Val Pro Glu Asn Arg Val Glu Thr Val 
225                 230                 235                 240 


Val Ala Asn Leu Thr Val Met Asp Arg Asp Gln Pro His Ser Pro Asn 
                245                 250                 255     


Trp Asn Ala Val Tyr Arg Ile Ile Ser Gly Asp Pro Ser Gly His Phe 
            260                 265                 270         


Ser Val Arg Thr Asp Pro Val Thr Asn Glu Gly Met Val Thr Val Val 
        275                 280                 285             


Lys Ala Val Asp Tyr Glu Leu Asn Arg Ala Phe Met Leu Thr Val Met 
    290                 295                 300                 


Val Ser Asn Gln Ala Pro Leu Ala Ser Gly Ile Gln Met Ser Phe Gln 
305                 310                 315                 320 


Ser Thr Ala Gly Val Thr Ile Ser Ile Met Asp Ile Asn Glu Ala Pro 
                325                 330                 335     


Tyr Phe Pro Ser Asn His Lys Leu Ile Arg Leu Glu Glu Gly Val Pro 
            340                 345                 350         


Pro Gly Thr Val Leu Thr Thr Phe Ser Ala Val Asp Pro Asp Arg Phe 
        355                 360                 365             


Met Gln Gln Ala Val Arg Tyr Ser Lys Leu Ser Asp Pro Ala Ser Trp 
    370                 375                 380                 


Leu His Ile Asn Ala Thr Asn Gly Gln Ile Thr Thr Ala Ala Val Leu 
385                 390                 395                 400 


Asp Arg Glu Ser Leu Tyr Thr Lys Asn Asn Val Tyr Glu Ala Thr Phe 
                405                 410                 415     


Leu Ala Ala Asp Asn Gly Ile Pro Pro Ala Ser Gly Thr Gly Thr Leu 
            420                 425                 430         


Gln Ile Tyr Leu Ile Asp Ile Asn Asp Asn Ala Pro Glu Leu Leu Pro 
        435                 440                 445             


Lys Glu Ala Gln Ile Cys Glu Lys Pro Asn Leu Asn Ala Ile Asn Ile 
    450                 455                 460                 


Thr Ala Ala Asp Ala Asp Val Asp Pro Asn Ile Gly Pro Tyr Val Phe 
465                 470                 475                 480 


Glu Leu Pro Phe Val Pro Ala Ala Val Arg Lys Asn Trp Thr Ile Thr 
                485                 490                 495     


Arg Leu Asn Gly Asp Tyr Ala Gln Leu Ser Leu Arg Ile Leu Tyr Leu 
            500                 505                 510         


Glu Ala Gly Met Tyr Asp Val Pro Ile Ile Val Thr Asp Ser Gly Asn 
        515                 520                 525             


Pro Pro Leu Ser Asn Thr Ser Ile Ile Lys Val Lys Val Cys Pro Cys 
    530                 535                 540                 


Asp Asp Asn Gly Asp Cys Thr Thr Ile Gly Ala Val Ala Ala Ala Gly 
545                 550                 555                 560 


Leu Gly Thr Gly Ala 
                565 


<210>  235
<211>  430
<212>  PRT
<213>  Homo Sapiens

<400>  235

Asp Trp Ile Trp Asn Gln Met His Ile Asp Glu Glu Lys Asn Thr Ser 
1               5                   10                  15      


Leu Pro His His Val Gly Lys Ile Lys Ser Ser Val Ser Arg Lys Asn 
            20                  25                  30          


Ala Lys Tyr Leu Leu Lys Gly Glu Tyr Val Gly Lys Val Phe Arg Val 
        35                  40                  45              


Asp Ala Glu Thr Gly Asp Val Phe Ala Ile Glu Arg Leu Asp Arg Glu 
    50                  55                  60                  


Asn Ile Ser Glu Tyr His Leu Thr Ala Val Ile Val Asp Lys Asp Thr 
65                  70                  75                  80  


Gly Glu Asn Leu Glu Thr Pro Ser Ser Phe Thr Ile Lys Val His Asp 
                85                  90                  95      


Val Asn Asp Asn Trp Pro Val Phe Thr His Arg Leu Phe Asn Ala Ser 
            100                 105                 110         


Val Pro Glu Ser Ser Ala Val Gly Thr Ser Val Ile Ser Val Thr Ala 
        115                 120                 125             


Val Asp Ala Asp Asp Pro Thr Val Gly Asp His Ala Ser Val Met Tyr 
    130                 135                 140                 


Gln Ile Leu Lys Gly Lys Glu Tyr Phe Ala Ile Asp Asn Ser Gly Arg 
145                 150                 155                 160 


Ile Ile Thr Ile Thr Lys Ser Leu Asp Arg Glu Lys Gln Ala Arg Tyr 
                165                 170                 175     


Glu Ile Val Val Glu Ala Arg Asp Ala Gln Gly Leu Arg Gly Asp Ser 
            180                 185                 190         


Gly Thr Ala Thr Val Leu Val Thr Leu Gln Asp Ile Asn Asp Asn Phe 
        195                 200                 205             


Pro Phe Phe Thr Gln Thr Lys Tyr Thr Phe Val Val Pro Glu Asp Thr 
    210                 215                 220                 


Arg Val Gly Thr Ser Val Gly Ser Leu Phe Val Glu Asp Pro Asp Glu 
225                 230                 235                 240 


Pro Gln Asn Arg Met Thr Lys Tyr Ser Ile Leu Arg Gly Asp Tyr Gln 
                245                 250                 255     


Asp Ala Phe Thr Ile Glu Thr Asn Pro Ala His Asn Glu Gly Ile Ile 
            260                 265                 270         


Lys Pro Met Lys Pro Leu Asp Tyr Glu Tyr Ile Gln Gln Tyr Ser Phe 
        275                 280                 285             


Ile Val Glu Ala Thr Asp Pro Thr Ile Asp Leu Arg Tyr Met Ser Pro 
    290                 295                 300                 


Pro Ala Gly Asn Arg Ala Gln Val Ile Ile Asn Ile Thr Asp Val Asp 
305                 310                 315                 320 


Glu Pro Pro Ile Phe Gln Leu Val Leu Gln Ile Ser Ala Ile Asp Lys 
                325                 330                 335     


Asp Ile Thr Pro Arg Asn Val Lys Phe Lys Phe Thr Leu Asn Thr Glu 
            340                 345                 350         


Asn Asn Phe Thr Leu Thr Asp Asn His Asp Asn Thr Ala Asn Ile Thr 
        355                 360                 365             


Val Lys Tyr Gly Gln Phe Asp Arg Glu His Thr Lys Val His Phe Leu 
    370                 375                 380                 


Pro Val Val Ile Ser Asp Asn Gly Met Pro Ser Arg Thr Gly Thr Ser 
385                 390                 395                 400 


Thr Leu Thr Val Ala Val Cys Lys Cys Asn Glu Gln Gly Glu Phe Thr 
                405                 410                 415     


Phe Cys Glu Asp Met Ala Ala Gln Val Asp Val Ser Ile Gln 
            420                 425                 430 


<210>  236
<211>  562
<212>  PRT
<213>  Homo Sapiens

<400>  236

Ser Trp Met Trp Asn Gln Phe Phe Leu Leu Glu Glu Tyr Thr Gly Ser 
1               5                   10                  15      


Asp Tyr Gln Tyr Val Gly Lys Leu His Ser Asp Gln Asp Arg Gly Asp 
            20                  25                  30          


Gly Ser Leu Lys Tyr Ile Leu Ser Gly Asp Gly Ala Gly Asp Leu Phe 
        35                  40                  45              


Ile Ile Asn Glu Asn Thr Gly Asp Ile Gln Ala Thr Lys Arg Leu Asp 
    50                  55                  60                  


Arg Glu Glu Lys Pro Val Tyr Ile Leu Arg Ala Gln Ala Ile Asn Arg 
65                  70                  75                  80  


Arg Thr Gly Arg Pro Val Glu Pro Glu Ser Glu Phe Ile Ile Lys Ile 
                85                  90                  95      


His Asp Ile Asn Asp Asn Glu Pro Ile Phe Thr Lys Glu Val Tyr Thr 
            100                 105                 110         


Ala Thr Val Pro Glu Met Ser Asp Val Gly Thr Phe Val Val Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Lys Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Glu Ser Glu 
145                 150                 155                 160 


Thr Gly Ile Ile Lys Thr Ala Leu Leu Asn Met Asp Arg Glu Asn Arg 
                165                 170                 175     


Glu Gln Tyr Gln Val Val Ile Gln Ala Lys Asp Met Gly Gly Gln Met 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Thr Val Asn Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Arg Phe Pro Gln Ser Thr Tyr Gln Phe Lys Thr 
    210                 215                 220                 


Pro Glu Ser Ser Pro Pro Gly Thr Pro Ile Gly Arg Ile Lys Ala Ser 
225                 230                 235                 240 


Asp Ala Asp Val Gly Glu Asn Ala Glu Ile Glu Tyr Ser Ile Thr Asp 
                245                 250                 255     


Gly Glu Gly Leu Asp Met Phe Asp Val Ile Thr Asp Gln Glu Thr Gln 
            260                 265                 270         


Glu Gly Ile Ile Thr Val Lys Lys Leu Leu Asp Phe Glu Lys Lys Lys 
        275                 280                 285             


Val Tyr Thr Leu Lys Val Glu Ala Ser Asn Pro Tyr Val Glu Pro Arg 
    290                 295                 300                 


Phe Leu Tyr Leu Gly Pro Phe Lys Asp Ser Ala Thr Val Arg Ile Val 
305                 310                 315                 320 


Val Glu Asp Val Asp Glu Pro Pro Val Phe Ser Lys Leu Ala Tyr Ile 
                325                 330                 335     


Leu Gln Ile Arg Glu Asp Ala Gln Ile Asn Thr Thr Ile Gly Ser Val 
            340                 345                 350         


Thr Ala Gln Asp Pro Asp Ala Ala Arg Asn Pro Val Lys Tyr Ser Val 
        355                 360                 365             


Asp Arg His Thr Asp Met Asp Arg Ile Phe Asn Ile Asp Ser Gly Asn 
    370                 375                 380                 


Gly Ser Ile Phe Thr Ser Lys Leu Leu Asp Arg Glu Thr Leu Leu Trp 
385                 390                 395                 400 


His Asn Ile Thr Val Ile Ala Thr Glu Ile Asn Asn Pro Lys Gln Ser 
                405                 410                 415     


Ser Arg Val Pro Leu Tyr Ile Lys Val Leu Asp Val Asn Asp Asn Ala 
            420                 425                 430         


Pro Glu Phe Ala Glu Phe Tyr Glu Thr Phe Val Cys Glu Lys Ala Lys 
        435                 440                 445             


Ala Asp Gln Leu Ile Gln Thr Leu His Ala Val Asp Lys Asp Asp Pro 
    450                 455                 460                 


Tyr Ser Gly His Gln Phe Ser Phe Ser Leu Ala Pro Glu Ala Ala Ser 
465                 470                 475                 480 


Gly Ser Asn Phe Thr Ile Gln Asp Asn Lys Asp Asn Thr Ala Gly Ile 
                485                 490                 495     


Leu Thr Arg Lys Asn Gly Tyr Asn Arg His Glu Met Ser Thr Tyr Leu 
            500                 505                 510         


Leu Pro Val Val Ile Ser Asp Asn Asp Tyr Pro Val Gln Ser Ser Thr 
        515                 520                 525             


Gly Thr Val Thr Val Arg Val Cys Ala Cys Asp His His Gly Asn Met 
    530                 535                 540                 


Gln Ser Cys His Ala Glu Ala Leu Ile His Pro Thr Gly Leu Ser Thr 
545                 550                 555                 560 


Gly Ala 
        


<210>  237
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  237

Ser Trp Val Trp Asn Gln Phe Phe Val Leu Glu Glu Tyr Met Gly Ser 
1               5                   10                  15      


Asp Pro Leu Tyr Val Gly Lys Leu His Ser Asp Val Asp Lys Gly Asp 
            20                  25                  30          


Gly Ser Ile Lys Tyr Ile Leu Ser Gly Glu Gly Ala Ser Ser Ile Phe 
        35                  40                  45              


Ile Ile Asp Glu Asn Thr Gly Asp Ile His Ala Thr Lys Arg Leu Asp 
    50                  55                  60                  


Arg Glu Glu Gln Ala Tyr Tyr Thr Leu Arg Ala Gln Ala Leu Asp Arg 
65                  70                  75                  80  


Leu Thr Asn Glu Pro Val Glu Pro Glu Ser Glu Phe Val Ile Lys Ile 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Glu Pro Lys Phe Leu Asp Gly Pro Tyr Thr 
            100                 105                 110         


Ala Gly Val Pro Glu Met Ser Pro Val Gly Thr Ser Val Val Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Thr Tyr Gly Asn Ser Ala Arg Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Glu Pro Lys 
145                 150                 155                 160 


Thr Gly Val Ile Lys Thr Ala Leu Pro Asn Met Asp Arg Glu Ala Lys 
                165                 170                 175     


Asp Gln Tyr Leu Leu Val Ile Gln Ala Lys Asp Met Val Gly Gln Asn 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Ser Val Thr Val Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Arg Phe Pro Arg Arg Ser Tyr Gln Tyr Asn Val 
    210                 215                 220                 


Pro Glu Ser Leu Pro Val Ala Ser Val Val Ala Arg Ile Lys Ala Ala 
225                 230                 235                 240 


Asp Ala Asp Ile Gly Ala Asn Ala Glu Met Glu Tyr Lys Ile Val Asp 
                245                 250                 255     


Gly Asp Gly Leu Gly Ile Phe Lys Ile Ser Val Asp Lys Glu Thr Gln 
            260                 265                 270         


Glu Gly Ile Ile Thr Ile Gln Lys Glu Leu Asp Phe Glu Ala Lys Thr 
        275                 280                 285             


Ser Tyr Thr Leu Arg Ile Glu Ala Ala Asn Lys Asp Ala Asp Pro Arg 
    290                 295                 300                 


Phe Leu Ser Leu Gly Pro Phe Ser Asp Thr Thr Thr Val Lys Ile Ile 
305                 310                 315                 320 


Val Glu Asp Val Asp Glu Pro Pro Val Phe Ser Ser Pro Leu Tyr Pro 
                325                 330                 335     


Met Glu Val Ser Glu Ala Thr Gln Val Gly Asn Ile Ile Gly Thr Val 
            340                 345                 350         


Ala Ala His Asp Pro Asp Ser Ser Asn Ser Pro Val Arg Tyr Ser Ile 
        355                 360                 365             


Asp Arg Asn Thr Asp Leu Glu Arg Tyr Phe Asn Ile Asp Ala Asn Ser 
    370                 375                 380                 


Gly Val Ile Thr Thr Ala Lys Ser Leu Asp Arg Glu Thr Asn Ala Ile 
385                 390                 395                 400 


His Asn Ile Thr Val Leu Ala Met Glu Ser Gln Asn Pro Ser Gln Val 
                405                 410                 415     


Gly Arg Gly Tyr Val Ala Ile Thr Ile Leu Asp Ile Asn Asp Asn Ala 
            420                 425                 430         


Pro Glu Phe Ala Met Asp Tyr Glu Thr Thr Val Cys Glu Asn Ala Gln 
        435                 440                 445             


Pro Gly Gln Val Ile Gln Lys Ile Ser Ala Val Asp Lys Asp Glu Pro 
    450                 455                 460                 


Ser Asn Gly His Gln Phe Tyr Phe Ser Leu Thr Thr Asp Ala Thr Asn 
465                 470                 475                 480 


Asn His Asn Phe Ser Leu Lys Asp Asn Lys Asp Asn Thr Ala Ser Ile 
                485                 490                 495     


Leu Thr Arg Arg Asn Gly Phe Arg Arg Gln Glu Gln Ser Val Tyr Tyr 
            500                 505                 510         


Leu Pro Ile Phe Ile Val Asp Ser Gly Ser Pro Ser Leu Ser Ser Thr 
        515                 520                 525             


Ser Thr Leu Thr Ile Arg Val Cys Asp Cys Asp Ala Asp Gly Val Ala 
    530                 535                 540                 


Gln Thr Cys Asn Ala Glu Ala Tyr Val Leu Pro Ala Gly Leu Ser Thr 
545                 550                 555                 560 


<210>  238
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  238

Gly Trp Val Trp Asn Gln Met Phe Val Leu Glu Glu Phe Ser Gly Pro 
1               5                   10                  15      


Glu Pro Ile Leu Val Gly Arg Leu His Thr Asp Leu Asp Pro Gly Ser 
            20                  25                  30          


Lys Lys Ile Lys Tyr Ile Leu Ser Gly Asp Gly Ala Gly Thr Ile Phe 
        35                  40                  45              


Gln Ile Asn Asp Val Thr Gly Asp Ile His Ala Ile Lys Arg Leu Asp 
    50                  55                  60                  


Arg Glu Glu Lys Ala Glu Tyr Thr Leu Thr Ala Gln Ala Val Asp Trp 
65                  70                  75                  80  


Glu Thr Ser Lys Pro Leu Glu Pro Pro Ser Glu Phe Ile Ile Lys Val 
                85                  90                  95      


Gln Asp Ile Asn Asp Asn Ala Pro Glu Phe Leu Asn Gly Pro Tyr His 
            100                 105                 110         


Ala Thr Val Pro Glu Met Ser Ile Leu Gly Thr Ser Val Thr Asn Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Pro Val Tyr Gly Asn Ser Ala Lys Leu 
    130                 135                 140                 


Val Tyr Ser Ile Leu Glu Gly Gln Pro Tyr Phe Ser Ile Glu Pro Glu 
145                 150                 155                 160 


Thr Ala Ile Ile Lys Thr Ala Leu Pro Asn Met Asp Arg Glu Ala Lys 
                165                 170                 175     


Glu Glu Tyr Leu Val Val Ile Gln Ala Lys Asp Met Gly Gly His Ser 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Thr Leu Thr Val Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asp Asn Pro Pro Lys Phe Ala Gln Ser Leu Tyr His Phe Ser Val 
    210                 215                 220                 


Pro Glu Asp Val Val Leu Gly Thr Ala Ile Gly Arg Val Lys Ala Asn 
225                 230                 235                 240 


Asp Gln Asp Ile Gly Glu Asn Ala Gln Ser Ser Tyr Asp Ile Ile Asp 
                245                 250                 255     


Gly Asp Gly Thr Ala Leu Phe Glu Ile Thr Ser Asp Ala Gln Ala Gln 
            260                 265                 270         


Asp Gly Ile Ile Arg Leu Arg Lys Pro Leu Asp Phe Glu Thr Lys Lys 
        275                 280                 285             


Ser Tyr Thr Leu Lys Val Glu Ala Ala Asn Val His Ile Asp Pro Arg 
    290                 295                 300                 


Phe Ser Gly Arg Gly Pro Phe Lys Asp Thr Ala Thr Val Lys Ile Val 
305                 310                 315                 320 


Val Glu Asp Ala Asp Glu Pro Pro Val Phe Ser Ser Pro Thr Tyr Leu 
                325                 330                 335     


Leu Glu Val His Glu Asn Ala Ala Leu Asn Ser Val Ile Gly Gln Val 
            340                 345                 350         


Thr Ala Arg Asp Pro Asp Ile Thr Ser Ser Pro Ile Arg Phe Ser Ile 
        355                 360                 365             


Asp Arg His Thr Asp Leu Glu Arg Gln Phe Asn Ile Asn Ala Asp Asp 
    370                 375                 380                 


Gly Lys Ile Thr Leu Ala Thr Pro Leu Asp Arg Glu Leu Ser Val Trp 
385                 390                 395                 400 


His Asn Ile Thr Ile Ile Ala Thr Glu Ile Arg Asn His Ser Gln Ile 
                405                 410                 415     


Ser Arg Val Pro Val Ala Ile Lys Val Leu Asp Val Asn Asp Asn Ala 
            420                 425                 430         


Pro Glu Phe Ala Ser Glu Tyr Glu Ala Phe Leu Cys Glu Asn Gly Lys 
        435                 440                 445             


Pro Gly Gln Val Ile Gln Thr Val Ser Ala Met Asp Lys Asp Asp Pro 
    450                 455                 460                 


Lys Asn Gly His Tyr Phe Leu Tyr Ser Leu Leu Pro Glu Met Val Asn 
465                 470                 475                 480 


Asn Pro Asn Phe Thr Ile Lys Lys Asn Glu Asp Asn Ser Leu Ser Ile 
                485                 490                 495     


Leu Ala Lys His Asn Gly Phe Asn Arg Gln Lys Gln Glu Val Tyr Leu 
            500                 505                 510         


Leu Pro Ile Ile Ile Ser Asp Ser Gly Asn Pro Pro Leu Ser Ser Thr 
        515                 520                 525             


Ser Thr Leu Thr Ile Arg Val Cys Gly Cys Ser Asn Asp Gly Val Val 
    530                 535                 540                 


Gln Ser Cys Asn Val Glu Ala Tyr Val Leu Pro Ile Gly Leu Ser Met 
545                 550                 555                 560 


<210>  239
<211>  562
<212>  PRT
<213>  Homo Sapiens

<400>  239

Gly Trp Met Trp Asn Gln Phe Phe Leu Leu Glu Glu Tyr Thr Gly Thr 
1               5                   10                  15      


Asp Thr Gln Tyr Val Gly Lys Leu His Thr Asp Gln Asp Lys Gly Asp 
            20                  25                  30          


Gly Asn Leu Lys Tyr Ile Leu Thr Gly Asp Gly Ala Gly Ser Leu Phe 
        35                  40                  45              


Val Ile Asp Glu Asn Thr Gly Asp Ile His Ala Ala Lys Lys Leu Asp 
    50                  55                  60                  


Arg Glu Glu Lys Ser Leu Tyr Ile Leu Arg Ala Lys Ala Ile Asp Arg 
65                  70                  75                  80  


Lys Thr Gly Arg Gln Val Glu Pro Glu Ser Glu Phe Ile Ile Lys Ile 
                85                  90                  95      


His Asp Ile Asn Asp Asn Glu Pro Lys Phe Thr Lys Asp Leu Tyr Thr 
            100                 105                 110         


Ala Ser Val Pro Glu Met Ser Gly Val Gly Thr Ser Val Ile Gln Val 
        115                 120                 125             


Thr Ala Thr Asp Ala Asp Asp Ala Asn Tyr Gly Asn Ser Ala Lys Val 
    130                 135                 140                 


Val Tyr Ser Ile Leu Gln Gly Gln Pro Tyr Phe Ser Val Asp Pro Glu 
145                 150                 155                 160 


Ser Gly Ile Ile Lys Thr Ala Leu Pro Asp Met Ser Arg Glu Asn Arg 
                165                 170                 175     


Glu Gln Tyr Gln Val Val Ile Gln Ala Lys Asp Met Gly Gly Gln Met 
            180                 185                 190         


Gly Gly Leu Ser Gly Thr Thr Thr Val Asn Ile Thr Leu Thr Asp Val 
        195                 200                 205             


Asn Asn Asn Pro Pro Arg Phe Pro Gln Ser Thr Tyr Gln Phe Asn Ser 
    210                 215                 220                 


Pro Glu Ser Val Pro Leu Gly Thr His Leu Gly Arg Ile Lys Ala Asn 
225                 230                 235                 240 


Asp Pro Asp Val Gly Glu Asn Ala Glu Met Glu Tyr Ser Ile Ala Glu 
                245                 250                 255     


Gly Asp Gly Ala Asp Met Phe Asp Val Ile Thr Asp Lys Asp Thr Gln 
            260                 265                 270         


Glu Gly Ile Ile Thr Val Lys Gln Asn Leu Asp Phe Glu Asn Gln Met 
        275                 280                 285             


Leu Tyr Thr Leu Arg Val Asp Ala Ser Asn Thr His Pro Asp Pro Arg 
    290                 295                 300                 


Phe Leu His Leu Gly Pro Phe Lys Asp Thr Ala Val Val Lys Ile Ser 
305                 310                 315                 320 


Val Glu Asp Ile Asp Glu Pro Pro Val Phe Thr Lys Val Ser Tyr Leu 
                325                 330                 335     


Ile Glu Val Asp Glu Asp Val Lys Glu Gly Ser Ile Ile Gly Gln Val 
            340                 345                 350         


Thr Ala Tyr Asp Pro Asp Ala Arg Asn Asn Leu Ile Lys Tyr Ser Val 
        355                 360                 365             


Asp Arg His Thr Asp Met Asp Arg Ile Phe Gly Ile His Ser Glu Asn 
    370                 375                 380                 


Gly Ser Ile Phe Thr Leu Lys Ala Leu Asp Arg Glu Ser Ser Pro Trp 
385                 390                 395                 400 


His Asn Ile Thr Val Thr Ala Thr Glu Ile Asn Asn Pro Lys Gln Ser 
                405                 410                 415     


Ser His Ile Pro Val Phe Ile Arg Ile Leu Asp Ile Asn Asp His Ala 
            420                 425                 430         


Pro Glu Phe Ala Met Tyr Tyr Glu Thr Phe Val Cys Glu Asn Ala Lys 
        435                 440                 445             


Pro Gly Gln Leu Ile Gln Thr Val Ser Val Met Asp Lys Asp Asp Pro 
    450                 455                 460                 


Pro Arg Gly His Lys Phe Phe Phe Glu Pro Val Pro Glu Phe Thr Leu 
465                 470                 475                 480 


Asn Pro Asn Phe Thr Ile Val Asp Asn Lys Asp Asn Thr Ala Gly Ile 
                485                 490                 495     


Met Thr Arg Lys Asp Gly Tyr Ser Arg Asn Lys Met Ser Thr Tyr Leu 
            500                 505                 510         


Leu Pro Ile Leu Ile Phe Asp Asn Asp Tyr Pro Ile Gln Ser Ser Thr 
        515                 520                 525             


Gly Thr Leu Thr Ile Arg Val Cys Ala Cys Asp Asn Gln Gly Asn Met 
    530                 535                 540                 


Gln Ser Cys Thr Ala Glu Ala Leu Ile Leu Ser Ala Gly Leu Ser Thr 
545                 550                 555                 560 


Gly Ala 
        


<210>  240
<211>  938
<212>  PRT
<213>  Homo Sapiens

<400>  240

Asp Leu Ala Pro Tyr Phe Thr Ser Glu Pro Leu Ser Ala Val Gln Lys 
1               5                   10                  15      


Leu Gly Gly Pro Val Val Leu His Cys Ser Ala Gln Pro Val Thr Thr 
            20                  25                  30          


Arg Ile Ser Trp Leu His Asn Gly Lys Thr Leu Asp Gly Asn Leu Glu 
        35                  40                  45              


His Ile Lys Ile His Gln Gly Thr Leu Thr Ile Leu Ser Leu Asn Ser 
    50                  55                  60                  


Ser Leu Leu Gly Tyr Tyr Gln Cys Leu Ala Asn Asn Ser Ile Gly Ala 
65                  70                  75                  80  


Ile Val Ser Gly Pro Ala Thr Val Ser Val Ala Val Leu Gly Asp Phe 
                85                  90                  95      


Gly Ser Ser Thr Lys His Val Ile Thr Ala Glu Glu Lys Ser Ala Gly 
            100                 105                 110         


Phe Ile Gly Cys Arg Val Pro Glu Ser Asn Pro Lys Ala Glu Val Arg 
        115                 120                 125             


Tyr Lys Ile Arg Gly Lys Trp Leu Glu His Ser Thr Glu Asn Tyr Leu 
    130                 135                 140                 


Ile Leu Pro Ser Gly Asn Leu Gln Ile Leu Asn Val Ser Leu Glu Asp 
145                 150                 155                 160 


Lys Gly Ser Tyr Lys Cys Ala Ala Tyr Asn Pro Val Thr His Gln Leu 
                165                 170                 175     


Lys Val Glu Pro Ile Gly Arg Lys Leu Leu Val Ser Arg Pro Ser Ser 
            180                 185                 190         


Asp Asp Val His Ile Leu His Pro Thr His Ser Gln Ala Leu Ala Val 
        195                 200                 205             


Leu Ser Arg Ser Pro Val Thr Leu Glu Cys Val Val Ser Gly Val Pro 
    210                 215                 220                 


Ala Pro Gln Val Tyr Trp Leu Lys Asp Gly Gln Asp Ile Ala Pro Glu 
225                 230                 235                 240 


Ser Asn Trp Arg Arg Leu Tyr Ser His Leu Ala Thr Asp Ser Val Asp 
                245                 250                 255     


Pro Ala Asp Ser Gly Asn Tyr Ser Cys Met Ala Gly Asn Lys Ser Gly 
            260                 265                 270         


Asp Val Lys Tyr Val Thr Tyr Met Val Asn Val Leu Glu His Ala Ser 
        275                 280                 285             


Ile Ser Lys Gly Leu Gln Asp Gln Ile Val Ser Leu Gly Ala Thr Val 
    290                 295                 300                 


His Phe Thr Cys Asp Val His Gly Asn Pro Ala Pro Asn Cys Thr Trp 
305                 310                 315                 320 


Phe His Asn Ala Gln Pro Ile His Pro Ser Ala Arg His Leu Thr Ala 
                325                 330                 335     


Gly Asn Gly Leu Lys Ile Ser Gly Val Thr Val Glu Asp Val Gly Met 
            340                 345                 350         


Tyr Gln Cys Val Ala Asp Asn Gly Ile Gly Phe Met His Ser Thr Gly 
        355                 360                 365             


Arg Leu Glu Ile Glu Asn Asp Gly Gly Phe Lys Pro Val Ile Ile Thr 
    370                 375                 380                 


Ala Pro Val Ser Ala Lys Val Ala Asp Gly Asp Phe Val Thr Leu Ser 
385                 390                 395                 400 


Cys Asn Ala Ser Gly Leu Pro Val Pro Val Ile Arg Trp Tyr Asp Ser 
                405                 410                 415     


His Gly Leu Ile Thr Ser His Pro Ser Gln Val Leu Arg Ser Lys Ser 
            420                 425                 430         


Arg Lys Ser Gln Leu Ser Arg Pro Glu Gly Leu Asn Leu Glu Pro Val 
        435                 440                 445             


Tyr Phe Val Leu Ser Gln Ala Gly Ala Ser Ser Leu His Ile Gln Ala 
    450                 455                 460                 


Val Thr Gln Glu His Ala Gly Lys Tyr Ile Cys Glu Ala Ala Asn Glu 
465                 470                 475                 480 


His Gly Thr Thr Gln Ala Glu Ala Ser Leu Met Val Val Pro Phe Glu 
                485                 490                 495     


Thr Asn Thr Lys Ala Glu Thr Val Thr Leu Pro Asp Ala Ala Gln Asn 
            500                 505                 510         


Asp Asp Arg Ser Lys Arg Asp Gly Ser Glu Thr Gly Leu Leu Ser Ser 
        515                 520                 525             


Phe Pro Val Lys Val His Pro Ser Ala Val Glu Ser Ala Pro Glu Lys 
    530                 535                 540                 


Asn Ala Ser Gly Ile Ser Val Pro Asp Ala Pro Ile Ile Leu Ser Pro 
545                 550                 555                 560 


Pro Gln Thr His Thr Pro Asp Thr Tyr Asn Leu Val Trp Arg Ala Gly 
                565                 570                 575     


Lys Asp Gly Gly Leu Pro Ile Asn Ala Tyr Phe Val Lys Tyr Arg Lys 
            580                 585                 590         


Leu Asp Asp Gly Val Gly Met Leu Gly Ser Trp His Thr Val Arg Val 
        595                 600                 605             


Pro Gly Ser Glu Asn Glu Leu His Leu Ala Glu Leu Glu Pro Ser Ser 
    610                 615                 620                 


Leu Tyr Glu Val Leu Met Val Ala Arg Ser Ala Ala Gly Glu Gly Gln 
625                 630                 635                 640 


Pro Ala Met Leu Thr Phe Arg Thr Ser Lys Glu Lys Thr Ala Ser Ser 
                645                 650                 655     


Lys Asn Thr Gln Ala Ser Ser Pro Pro Val Gly Ile Pro Lys Tyr Pro 
            660                 665                 670         


Val Val Ser Glu Ala Ala Asn Asn Asn Phe Gly Val Val Leu Thr Asp 
        675                 680                 685             


Ser Ser Arg His Ser Gly Val Pro Glu Ala Pro Asp Arg Pro Thr Ile 
    690                 695                 700                 


Ser Thr Ala Ser Glu Thr Ser Val Tyr Val Thr Trp Ile Pro Arg Ala 
705                 710                 715                 720 


Asn Gly Gly Ser Pro Ile Thr Ala Phe Lys Val Glu Tyr Lys Arg Met 
                725                 730                 735     


Arg Thr Ser Asn Trp Leu Val Ala Ala Glu Asp Ile Pro Pro Ser Lys 
            740                 745                 750         


Leu Ser Val Glu Val Arg Ser Leu Glu Pro Gly Ser Thr Tyr Lys Phe 
        755                 760                 765             


Arg Val Ile Ala Ile Asn His Tyr Gly Glu Ser Phe Arg Ser Ser Ala 
    770                 775                 780                 


Ser Arg Pro Tyr Gln Val Val Gly Phe Pro Asn Arg Phe Ser Ser Arg 
785                 790                 795                 800 


Pro Ile Thr Gly Pro His Ile Ala Tyr Thr Glu Ala Val Ser Asp Thr 
                805                 810                 815     


Gln Ile Met Leu Lys Trp Thr Tyr Ile Pro Ser Ser Asn Asn Asn Thr 
            820                 825                 830         


Pro Ile Gln Gly Phe Tyr Ile Tyr Tyr Arg Pro Thr Asp Ser Asp Asn 
        835                 840                 845             


Asp Ser Asp Tyr Lys Arg Asp Val Val Glu Gly Ser Lys Gln Trp His 
    850                 855                 860                 


Met Ile Gly His Leu Gln Pro Glu Thr Ser Tyr Asp Ile Lys Met Gln 
865                 870                 875                 880 


Cys Phe Asn Glu Gly Gly Glu Ser Glu Phe Ser Asn Val Met Ile Cys 
                885                 890                 895     


Glu Thr Lys Val Lys Arg Val Pro Gly Ala Ser Glu Tyr Pro Val Lys 
            900                 905                 910         


Asp Leu Ser Thr Pro Pro Asn Ser Leu Gly Ser Gly Gly Asn Val Gly 
        915                 920                 925             


Pro Ala Thr Ser Pro Ala Arg Ser Ser Asp 
    930                 935             


<210>  241
<211>  320
<212>  PRT
<213>  Homo Sapiens

<400>  241

Gln Lys Leu Ser Lys His Lys Thr Pro Ala Gln Pro Gln Leu Lys Ala 
1               5                   10                  15      


Ala Asn Cys Cys Glu Glu Val Lys Glu Leu Lys Ala Gln Val Ala Asn 
            20                  25                  30          


Leu Ser Ser Leu Leu Ser Glu Leu Asn Lys Lys Gln Glu Arg Asp Trp 
        35                  40                  45              


Val Ser Val Val Met Gln Val Met Glu Leu Glu Ser Asn Ser Lys Arg 
    50                  55                  60                  


Met Glu Ser Arg Leu Thr Asp Ala Glu Ser Lys Tyr Ser Glu Met Asn 
65                  70                  75                  80  


Asn Gln Ile Asp Ile Met Gln Leu Gln Ala Ala Gln Thr Val Thr Gln 
                85                  90                  95      


Thr Ser Ala Asp Ala Ile Tyr Asp Cys Ser Ser Leu Tyr Gln Lys Asn 
            100                 105                 110         


Tyr Arg Ile Ser Gly Val Tyr Lys Leu Pro Pro Asp Asp Phe Leu Gly 
        115                 120                 125             


Ser Pro Glu Leu Glu Val Phe Cys Asp Met Glu Thr Ser Gly Gly Gly 
    130                 135                 140                 


Trp Thr Ile Ile Gln Arg Arg Lys Ser Gly Leu Val Ser Phe Tyr Arg 
145                 150                 155                 160 


Asp Trp Lys Gln Tyr Lys Gln Gly Phe Gly Ser Ile Arg Gly Asp Phe 
                165                 170                 175     


Trp Leu Gly Asn Glu His Ile His Arg Leu Ser Arg Gln Pro Thr Arg 
            180                 185                 190         


Leu Arg Val Glu Met Glu Asp Trp Glu Gly Asn Leu Arg Tyr Ala Glu 
        195                 200                 205             


Tyr Ser His Phe Val Leu Gly Asn Glu Leu Asn Ser Tyr Arg Leu Phe 
    210                 215                 220                 


Leu Gly Asn Tyr Thr Gly Asn Val Gly Asn Asp Ala Leu Gln Tyr His 
225                 230                 235                 240 


Asn Asn Thr Ala Phe Ser Thr Lys Asp Lys Asp Asn Asp Asn Cys Leu 
                245                 250                 255     


Asp Lys Cys Ala Gln Leu Arg Lys Gly Gly Tyr Trp Tyr Asn Cys Cys 
            260                 265                 270         


Thr Asp Ser Asn Leu Asn Gly Val Tyr Tyr Arg Leu Gly Glu His Asn 
        275                 280                 285             


Lys His Leu Asp Gly Ile Thr Trp Tyr Gly Trp His Gly Ser Thr Tyr 
    290                 295                 300                 


Ser Leu Lys Arg Val Glu Met Lys Ile Arg Pro Glu Asp Phe Lys Pro 
305                 310                 315                 320 


<210>  242
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  242

Gln Leu Thr Thr Glu Ser Met Pro Phe Asn Val Ala Glu Gly Lys Glu 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Gln Leu Phe Gly Tyr Ser 
            20                  25                  30          


Trp Tyr Lys Gly Glu Arg Val Asp Gly Asn Arg Gln Ile Val Gly Tyr 
        35                  40                  45              


Ala Ile Gly Thr Gln Gln Ala Thr Pro Gly Pro Ala Asn Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Pro Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Gln 
65                  70                  75                  80  


Asn Asp Thr Gly Phe Tyr Thr Leu Gln Val Ile Lys Ser Asp Leu Val 
                85                  90                  95      


Asn Glu Glu Ala Thr Gly Gln Phe His Val Tyr Pro Glu Leu Pro Lys 
            100                 105                 110         


Pro Ser Ile Ser Ser Asn Asn Ser Asn Pro Val Glu Asp Lys Asp Ala 
        115                 120                 125             


Val Ala Phe Thr Cys Glu Pro Glu Thr Gln Asp Thr Thr Tyr Leu Trp 
    130                 135                 140                 


Trp Ile Asn Asn Gln Ser Leu Pro Val Ser Pro Arg Leu Gln Leu Ser 
145                 150                 155                 160 


Asn Gly Asn Arg Thr Leu Thr Leu Leu Ser Val Thr Arg Asn Asp Thr 
                165                 170                 175     


Gly Pro Tyr Glu Cys Glu Ile Gln Asn Pro Val Ser Ala Asn Arg Ser 
            180                 185                 190         


Asp Pro Val Thr Leu Asn Val Thr Tyr Gly Pro Asp Thr Pro Thr Ile 
        195                 200                 205             


Ser Pro Ser Asp Thr Tyr Tyr Arg Pro Gly Ala Asn Leu Ser Leu Ser 
    210                 215                 220                 


Cys Tyr Ala Ala Ser Asn Pro Pro Ala Gln Tyr Ser Trp Leu Ile Asn 
225                 230                 235                 240 


Gly Thr Phe Gln Gln Ser Thr Gln Glu Leu Phe Ile Pro Asn Ile Thr 
                245                 250                 255     


Val Asn Asn Ser Gly Ser Tyr Thr Cys His Ala Asn Asn Ser Val Thr 
            260                 265                 270         


Gly Cys Asn Arg Thr Thr Val Lys Thr Ile Ile Val Thr Glu Leu Ser 
        275                 280                 285             


Pro Val Val Ala Lys Pro Gln Ile Lys Ala Ser Lys Thr Thr Val Thr 
    290                 295                 300                 


Gly Asp Lys Asp Ser Val Asn Leu Thr Cys Ser Thr Asn Asp Thr Gly 
305                 310                 315                 320 


Ile Ser Ile Arg Trp Phe Phe Lys Asn Gln Ser Leu Pro Ser Ser Glu 
                325                 330                 335     


Arg Met Lys Leu Ser Gln Gly Asn Thr Thr Leu Ser Ile Asn Pro Val 
            340                 345                 350         


Lys Arg Glu Asp Ala Gly Thr Tyr Trp Cys Glu Val Phe Asn Pro Ile 
        355                 360                 365             


Ser Lys Asn Gln Ser Asp Pro Ile Met Leu Asn Val Asn Tyr Asn Ala 
    370                 375                 380                 


Leu Pro Gln Glu Asn Gly Leu Ser Pro Gly 
385                 390                 


<210>  243
<211>  405
<212>  PRT
<213>  Homo Sapiens

<400>  243

Glu Ile Ser Ile Thr Leu Glu Pro Ala Gln Pro Ser Glu Gly Asp Asn 
1               5                   10                  15      


Val Thr Leu Val Val His Gly Leu Ser Gly Glu Leu Leu Ala Tyr Ser 
            20                  25                  30          


Trp Tyr Ala Gly Pro Thr Leu Ser Val Ser Tyr Leu Val Ala Ser Tyr 
        35                  40                  45              


Ile Val Ser Thr Gly Asp Glu Thr Pro Gly Pro Ala His Thr Gly Arg 
    50                  55                  60                  


Glu Ala Val Arg Pro Asp Gly Ser Leu Asp Ile Gln Gly Ile Leu Pro 
65                  70                  75                  80  


Arg His Ser Gly Thr Tyr Ile Leu Gln Thr Phe Asn Arg Gln Leu Gln 
                85                  90                  95      


Thr Glu Val Gly Tyr Gly His Val Gln Val His Glu Ile Leu Ala Gln 
            100                 105                 110         


Pro Thr Val Leu Ala Asn Ser Thr Ala Leu Val Glu Arg Arg Asp Thr 
        115                 120                 125             


Leu Arg Leu Met Cys Ser Ser Pro Ser Pro Thr Ala Glu Val Arg Trp 
    130                 135                 140                 


Phe Phe Asn Gly Gly Ala Leu Pro Val Ala Leu Arg Leu Gly Leu Ser 
145                 150                 155                 160 


Pro Asp Gly Arg Val Leu Ala Arg His Gly Ile Arg Arg Glu Glu Ala 
                165                 170                 175     


Gly Ala Tyr Gln Cys Glu Val Trp Asn Pro Val Ser Val Ser Arg Ser 
            180                 185                 190         


Glu Pro Ile Asn Leu Thr Val Tyr Phe Gly Pro Glu Arg Val Ala Ile 
        195                 200                 205             


Leu Gln Asp Ser Thr Thr Arg Thr Gly Cys Thr Ile Lys Val Asp Phe 
    210                 215                 220                 


Asn Thr Ser Leu Thr Leu Trp Cys Val Ser Arg Ser Cys Pro Glu Pro 
225                 230                 235                 240 


Glu Tyr Val Trp Thr Phe Asn Gly Gln Ala Leu Lys Asn Gly Gln Asp 
                245                 250                 255     


His Leu Asn Ile Ser Ser Met Thr Ala Ala Gln Glu Gly Thr Tyr Thr 
            260                 265                 270         


Cys Ile Ala Lys Asn Thr Lys Thr Leu Leu Ser Gly Ser Ala Ser Val 
        275                 280                 285             


Val Val Lys Leu Ser Ala Ala Ala Val Ala Thr Met Ile Val Pro Val 
    290                 295                 300                 


Pro Thr Lys Pro Thr Glu Gly Gln Asp Val Thr Leu Thr Val Gln Gly 
305                 310                 315                 320 


Tyr Pro Lys Asp Leu Leu Val Tyr Ala Trp Tyr Arg Gly Pro Ala Ser 
                325                 330                 335     


Glu Pro Asn Arg Leu Leu Ser Gln Leu Pro Ser Gly Thr Trp Ile Ala 
            340                 345                 350         


Gly Pro Ala His Thr Gly Arg Glu Val Gly Phe Pro Asn Cys Ser Leu 
        355                 360                 365             


Leu Val Gln Lys Leu Asn Leu Thr Asp Thr Gly Arg Tyr Thr Leu Lys 
    370                 375                 380                 


Thr Val Thr Val Gln Gly Lys Thr Glu Thr Leu Glu Val Glu Leu Gln 
385                 390                 395                 400 


Val Ala Pro Leu Gly 
                405 


<210>  244
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  244

Gln Ile Phe Ile Thr Gln Thr Leu Gly Ile Lys Gly Tyr Arg Thr Val 
1               5                   10                  15      


Val Ala Leu Asp Lys Val Pro Glu Asp Val Gln Glu Tyr Ser Trp Tyr 
            20                  25                  30          


Trp Gly Ala Asn Asp Ser Ala Gly Asn Met Ile Ile Ser His Lys Pro 
        35                  40                  45              


Pro Ser Ala Gln Gln Pro Gly Pro Met Tyr Thr Gly Arg Glu Arg Val 
    50                  55                  60                  


Asn Arg Glu Gly Ser Leu Leu Ile Arg Pro Thr Ala Leu Asn Asp Thr 
65                  70                  75                  80  


Gly Asn Tyr Thr Val Arg Val Val Ala Gly Asn Glu Thr Gln Arg Ala 
                85                  90                  95      


Thr Gly Trp Leu Glu Val Leu Glu Leu Gly Ser Asn Leu Gly Ile Ser 
            100                 105                 110         


Val Asn Ala Ser Ser Leu Val Glu Asn Met Asp Ser Val Ala Ala Asp 
        115                 120                 125             


Cys Leu Thr Asn Val Thr Asn Ile Thr Trp Tyr Val Asn Asp Val Pro 
    130                 135                 140                 


Thr Ser Ser Ser Asp Arg Met Thr Ile Ser Pro Asp Gly Lys Thr Leu 
145                 150                 155                 160 


Val Ile Leu Arg Val Ser Arg Tyr Asp Arg Thr Ile Gln Cys Met Ile 
                165                 170                 175     


Glu Ser Phe Pro Glu Ile Phe Gln Arg Ser Glu Arg Ile Ser Leu Thr 
            180                 185                 190         


Val Ala Tyr Gly Pro Asp Tyr Val Leu Leu Arg Ser Asn Pro Asp Asp 
        195                 200                 205             


Phe Asn Gly Ile Val Thr Ala Glu Ile Gly Ser Gln Val Glu Met Glu 
    210                 215                 220                 


Cys Ile Cys Tyr Ser Phe Leu Asp Leu Lys Tyr His Trp Ile His Asn 
225                 230                 235                 240 


Gly Ser Leu Leu Asn Phe Ser Asp Ala Lys Met Asn Leu Ser Ser Leu 
                245                 250                 255     


Ala Trp Glu Gln Met Gly Arg Tyr Arg Cys Thr Val Glu Asn Pro Val 
            260                 265                 270         


Thr Gln Leu Ile Met Tyr Met Asp Val Arg Ile Gln Ala Pro His Glu 
        275                 280                 285             


Asp Leu Thr Cys Cys Pro Gln Arg Phe Leu His Leu Arg Ile His Gly 
    290                 295                 300                 


Asp Val Pro His His Ala Asp Ser Ala Gly Trp Arg Leu His Leu Trp 
305                 310                 315                 320 


Ser Pro Asp Pro Cys Ser Asp Gln Pro Leu Leu Asn Gln Asp Lys Ser 
                325                 330                 335     


Gly Ser Met Ser Val His Pro Arg Pro Glu Asp Lys Thr Arg Arg Ala 
            340                 345                 350         


Ser Arg 
        


<210>  245
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  245

Ala Leu Tyr Ile Gln Lys Ile Pro Glu Gln Pro Gln Lys Asn Gln Asp 
1               5                   10                  15      


Leu Leu Leu Ser Val Gln Gly Val Pro Asp Thr Phe Gln Asp Phe Asn 
            20                  25                  30          


Trp Tyr Leu Gly Glu Glu Thr Tyr Gly Gly Thr Arg Leu Phe Thr Tyr 
        35                  40                  45              


Ile Pro Gly Ile Gln Arg Pro Gln Arg Asp Gly Ser Ala Met Gly Gln 
    50                  55                  60                  


Arg Asp Ile Val Gly Phe Pro Asn Gly Ser Met Leu Leu Arg Arg Ala 
65                  70                  75                  80  


Gln Pro Thr Asp Ser Gly Thr Tyr Gln Val Ala Ile Thr Ile Asn Ser 
                85                  90                  95      


Glu Trp Thr Met Lys Ala Lys Thr Glu Val Gln Val Ala Glu Lys Asn 
            100                 105                 110         


Lys Glu Leu Pro Ser Thr His Leu Pro Thr Asn Ala Gly 
        115                 120                 125 


<210>  246
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  246

Gln Leu Thr Leu Asn Ala Asn Pro Leu Asp Ala Thr Gln Ser Glu Asp 
1               5                   10                  15      


Val Val Leu Pro Val Phe Gly Thr Pro Arg Thr Pro Gln Ile His Gly 
            20                  25                  30          


Arg Ser Arg Glu Leu Ala Lys Pro Ser Ile Ala Val Ser Pro Gly Thr 
        35                  40                  45              


Ala Ile Glu Gln Lys Asp Met Val Thr Phe Tyr Cys Thr Thr Lys Asp 
    50                  55                  60                  


Val Asn Ile Thr Ile His Trp Val Ser Asn Asn Leu Ser Ile Val Phe 
65                  70                  75                  80  


His Glu Arg Met Gln Leu Ser Lys Asp Gly Lys Ile Leu Thr Ile Leu 
                85                  90                  95      


Ile Val Gln Arg Glu Asp Ser Gly Thr Tyr Gln Cys Glu Ala Arg Asp 
            100                 105                 110         


Ala Leu Leu Ser Gln Arg Ser Asp Pro Ile Phe Leu Asp Val Lys Tyr 
        115                 120                 125             


Gly Pro Asp Pro Val Glu Ile Lys Leu Glu Ser Gly Val Ala Ser Gly 
    130                 135                 140                 


Glu Val Val Glu Val Met Glu Gly Ser Ser Met Thr Phe Leu Ala Glu 
145                 150                 155                 160 


Thr Lys Ser His Pro Pro Cys Ala Tyr Thr Trp Phe Leu Leu Asp Ser 
                165                 170                 175     


Ile Leu Ser His Thr Thr Arg Thr Phe Thr Ile His Ala Val Ser Arg 
            180                 185                 190         


Glu His Glu Gly Leu Tyr Arg Cys Leu Val Ser Asn Ser Ala Thr His 
        195                 200                 205             


Leu Ser Ser Leu Gly Thr Leu Lys Val Arg Val Leu Glu Thr Leu Thr 
    210                 215                 220                 


Met Pro Gln Val Val Pro Ser Ser Leu Asn Leu Val Glu Asn Ala Arg 
225                 230                 235                 240 


Ser Val Asp Leu Thr Cys Gln Thr Val Asn Gln Ser Val Asn Val Gln 
                245                 250                 255     


Trp Phe Leu Ser Gly Gln Pro Leu Leu Pro Ser Glu His Leu Gln Leu 
            260                 265                 270         


Ser Ala Asp Asn Arg Thr Leu Ile Ile His Gly Leu Gln Arg Asn Asp 
        275                 280                 285             


Thr Gly Pro Tyr Ala Cys Glu Val Trp Asn Trp Gly Ser Arg Ala Arg 
    290                 295                 300                 


Ser Glu Pro Leu Glu Leu Thr Ile Asn Tyr Gly Pro Asp Gln Val His 
305                 310                 315                 320 


Ile Thr Arg Glu Ser Ala Ser Glu Met Ile Ser Thr Ile Glu Ala Glu 
                325                 330                 335     


Leu Asn Ser Ser Leu Thr Leu Gln Cys Trp Ala Glu Ser Lys Pro Gly 
            340                 345                 350         


Ala Glu Tyr Arg Trp Thr Leu Glu His Ser Thr Gly Glu His Leu Gly 
        355                 360                 365             


Glu Gln Leu Ile Ile Arg Ala Leu Thr Trp Glu His Asp Gly Ile Tyr 
    370                 375                 380                 


Asn Cys Thr Ala Ser Asn Ser Leu Thr Gly Leu Ala Arg Ser Thr Ser 
385                 390                 395                 400 


Val Leu Val Lys Val Val Gly Pro Gln Ser Ser Ser Leu Ser Ser Gly 
                405                 410                 415     


Ala Ile Ala Gly 
            420 


<210>  247
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  247

Trp Leu Phe Ile Ala Ser Ala Pro Phe Glu Val Ala Glu Gly Glu Asn 
1               5                   10                  15      


Val His Leu Ser Val Val Tyr Leu Pro Glu Asn Leu Tyr Ser Tyr Gly 
            20                  25                  30          


Trp Tyr Lys Gly Lys Thr Val Glu Pro Asn Gln Leu Ile Ala Ala Tyr 
        35                  40                  45              


Val Ile Asp Thr His Val Arg Thr Pro Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ile Ser Pro Ser Gly Asp Leu His Phe Gln Asn Val Thr Leu 
65                  70                  75                  80  


Glu Asp Thr Gly Tyr Tyr Asn Leu Gln Val Thr Tyr Arg Asn Ser Gln 
                85                  90                  95      


Ile Glu Gln Ala Ser His His Leu Arg Val Tyr Glu Ser Val Ala Gln 
            100                 105                 110         


Pro Ser Ile Gln Ala Ser Ser Thr Thr Val Thr Glu Lys Gly Ser Val 
        115                 120                 125             


Val Leu Thr Cys His Thr Asn Asn Thr Gly Thr Ser Phe Gln Trp Ile 
    130                 135                 140                 


Phe Asn Asn Gln Arg Leu Gln Val Thr Lys Arg Met Lys Leu Ser Trp 
145                 150                 155                 160 


Phe Asn His Val Leu Thr Ile Asp Pro Ile Arg Gln Glu Asp Ala Gly 
                165                 170                 175     


Glu Tyr Gln Cys Glu Val Ser Asn Pro Val Ser Ser Asn Arg Ser Asp 
            180                 185                 190         


Pro Leu Lys Leu Thr Val Lys Ser Asp Asp Asn Thr Leu Gly 
        195                 200                 205     


<210>  248
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  248

Lys Leu Thr Ile Glu Ser Met Pro Leu Ser Val Ala Glu Gly Lys Glu 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln His Leu Phe Gly Tyr Ser 
            20                  25                  30          


Trp Tyr Lys Gly Glu Arg Val Asp Gly Asn Ser Leu Ile Val Gly Tyr 
        35                  40                  45              


Val Ile Gly Thr Gln Gln Ala Thr Pro Gly Ala Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Thr Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Gln 
65                  70                  75                  80  


Asn Asp Ile Gly Phe Tyr Thr Leu Gln Val Ile Lys Ser Asp Leu Val 
                85                  90                  95      


Asn Glu Glu Ala Thr Gly Gln Phe His Val Tyr Gln Glu Asn Ala Pro 
            100                 105                 110         


Gly Leu Pro Val Gly Ala Val Ala Gly 
        115                 120     


<210>  249
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  249

Phe Thr Ile Glu Ala Leu Pro Ser Ser Ala Ala Glu Gly Lys Asp Val 
1               5                   10                  15      


Leu Leu Leu Ala Cys Asn Ile Ser Glu Thr Ile Gln Ala Tyr Tyr Trp 
            20                  25                  30          


His Lys Gly Lys Thr Ala Glu Gly Ser Pro Leu Ile Ala Gly Tyr Ile 
        35                  40                  45              


Thr Asp Ile Gln Ala Asn Ile Pro Gly Ala Ala Tyr Ser Gly Arg Glu 
    50                  55                  60                  


Thr Val Tyr Pro Asn Gly Ser Leu Leu Phe Gln Asn Ile Thr Leu Glu 
65                  70                  75                  80  


Asp Ala Gly Ser Tyr Thr Leu Arg Thr Ile Asn Ala Ser Tyr Asp Ser 
                85                  90                  95      


Asp Gln Ala Thr Gly Gln Leu His Val His Gln Asn Asn Val Pro Gly 
            100                 105                 110         


Leu Pro Val Gly Ala Val Ala Gly 
        115                 120 


<210>  250
<211>  651
<212>  PRT
<213>  Homo Sapiens

<400>  250

Lys Leu Thr Ile Glu Ser Thr Pro Phe Asn Val Ala Glu Gly Lys Glu 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln His Leu Phe Gly Tyr Ser 
            20                  25                  30          


Trp Tyr Lys Gly Glu Arg Val Asp Gly Asn Arg Gln Ile Ile Gly Tyr 
        35                  40                  45              


Val Ile Gly Thr Gln Gln Ala Thr Pro Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Ile Ile Tyr Pro Asn Ala Ser Leu Leu Ile Gln Asn Ile Ile Gln 
65                  70                  75                  80  


Asn Asp Thr Gly Phe Tyr Thr Leu His Val Ile Lys Ser Asp Leu Val 
                85                  90                  95      


Asn Glu Glu Ala Thr Gly Gln Phe Arg Val Tyr Pro Glu Leu Pro Lys 
            100                 105                 110         


Pro Ser Ile Ser Ser Asn Asn Ser Lys Pro Val Glu Asp Lys Asp Ala 
        115                 120                 125             


Val Ala Phe Thr Cys Glu Pro Glu Thr Gln Asp Ala Thr Tyr Leu Trp 
    130                 135                 140                 


Trp Val Asn Asn Gln Ser Leu Pro Val Ser Pro Arg Leu Gln Leu Ser 
145                 150                 155                 160 


Asn Gly Asn Arg Thr Leu Thr Leu Phe Asn Val Thr Arg Asn Asp Ser 
                165                 170                 175     


Ala Ser Tyr Lys Cys Glu Thr Gln Asn Pro Val Ser Ala Arg Arg Ser 
            180                 185                 190         


Asp Ser Val Ile Leu Asn Val Leu Tyr Gly Pro Asp Ala Pro Thr Ile 
        195                 200                 205             


Ser Pro Leu Asn Thr Ser Tyr Arg Ser Gly Glu Asn Leu Asn Leu Ser 
    210                 215                 220                 


Cys His Ala Ala Ser Asn Pro Pro Ala Gln Tyr Ser Trp Phe Val Asn 
225                 230                 235                 240 


Gly Thr Phe Gln Gln Ser Thr Gln Glu Leu Phe Ile Pro Asn Ile Thr 
                245                 250                 255     


Val Asn Asn Ser Gly Ser Tyr Thr Cys Gln Ala His Asn Ser Asp Thr 
            260                 265                 270         


Gly Leu Asn Arg Thr Thr Val Thr Thr Ile Thr Val Tyr Ala Glu Pro 
        275                 280                 285             


Pro Lys Pro Phe Ile Thr Ser Asn Asn Ser Asn Pro Val Glu Asp Glu 
    290                 295                 300                 


Asp Ala Val Ala Leu Thr Cys Glu Pro Glu Ile Gln Asn Thr Thr Tyr 
305                 310                 315                 320 


Leu Trp Trp Val Asn Asn Gln Ser Leu Pro Val Ser Pro Arg Leu Gln 
                325                 330                 335     


Leu Ser Asn Asp Asn Arg Thr Leu Thr Leu Leu Ser Val Thr Arg Asn 
            340                 345                 350         


Asp Val Gly Pro Tyr Glu Cys Gly Ile Gln Asn Glu Leu Ser Val Asp 
        355                 360                 365             


His Ser Asp Pro Val Ile Leu Asn Val Leu Tyr Gly Pro Asp Asp Pro 
    370                 375                 380                 


Thr Ile Ser Pro Ser Tyr Thr Tyr Tyr Arg Pro Gly Val Asn Leu Ser 
385                 390                 395                 400 


Leu Ser Cys His Ala Ala Ser Asn Pro Pro Ala Gln Tyr Ser Trp Leu 
                405                 410                 415     


Ile Asp Gly Asn Ile Gln Gln His Thr Gln Glu Leu Phe Ile Ser Asn 
            420                 425                 430         


Ile Thr Glu Lys Asn Ser Gly Leu Tyr Thr Cys Gln Ala Asn Asn Ser 
        435                 440                 445             


Ala Ser Gly His Ser Arg Thr Thr Val Lys Thr Ile Thr Val Ser Ala 
    450                 455                 460                 


Glu Leu Pro Lys Pro Ser Ile Ser Ser Asn Asn Ser Lys Pro Val Glu 
465                 470                 475                 480 


Asp Lys Asp Ala Val Ala Phe Thr Cys Glu Pro Glu Ala Gln Asn Thr 
                485                 490                 495     


Thr Tyr Leu Trp Trp Val Asn Gly Gln Ser Leu Pro Val Ser Pro Arg 
            500                 505                 510         


Leu Gln Leu Ser Asn Gly Asn Arg Thr Leu Thr Leu Phe Asn Val Thr 
        515                 520                 525             


Arg Asn Asp Ala Arg Ala Tyr Val Cys Gly Ile Gln Asn Ser Val Ser 
    530                 535                 540                 


Ala Asn Arg Ser Asp Pro Val Thr Leu Asp Val Leu Tyr Gly Pro Asp 
545                 550                 555                 560 


Thr Pro Ile Ile Ser Pro Pro Asp Ser Ser Tyr Leu Ser Gly Ala Asn 
                565                 570                 575     


Leu Asn Leu Ser Cys His Ser Ala Ser Asn Pro Ser Pro Gln Tyr Ser 
            580                 585                 590         


Trp Arg Ile Asn Gly Ile Pro Gln Gln His Thr Gln Val Leu Phe Ile 
        595                 600                 605             


Ala Lys Ile Thr Pro Asn Asn Asn Gly Thr Tyr Ala Cys Phe Val Ser 
    610                 615                 620                 


Asn Leu Ala Thr Gly Arg Asn Asn Ser Ile Val Lys Ser Ile Thr Val 
625                 630                 635                 640 


Ser Ala Ser Gly Thr Ser Pro Gly Leu Ser Ala 
                645                 650     


<210>  251
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  251

Lys Leu Thr Ile Glu Ser Thr Pro Phe Asn Val Ala Glu Gly Lys Glu 
1               5                   10                  15      


Val Leu Leu Leu Ala His Asn Leu Pro Gln Asn Arg Ile Gly Tyr Ser 
            20                  25                  30          


Trp Tyr Lys Gly Glu Arg Val Asp Gly Asn Ser Leu Ile Val Gly Tyr 
        35                  40                  45              


Val Ile Gly Thr Gln Gln Ala Thr Pro Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Pro Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Gln 
65                  70                  75                  80  


Asn Asp Thr Gly Phe Tyr Thr Leu Gln Val Ile Lys Ser Asp Leu Val 
                85                  90                  95      


Asn Glu Glu Ala Thr Gly Gln Phe His Val Tyr Pro Glu Leu Pro Lys 
            100                 105                 110         


Pro Ser Ile Ser Ser Asn Asn Ser Asn Pro Val Glu Asp Lys Asp Ala 
        115                 120                 125             


Val Ala Phe Thr Cys Glu Pro Glu Val Gln Asn Thr Thr Tyr Leu Trp 
    130                 135                 140                 


Trp Val Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Leu Gln Leu Ser 
145                 150                 155                 160 


Asn Gly Asn Met Thr Leu Thr Leu Leu Ser Val Lys Arg Asn Asp Ala 
                165                 170                 175     


Gly Ser Tyr Glu Cys Glu Ile Gln Asn Pro Ala Ser Ala Asn Arg Ser 
            180                 185                 190         


Asp Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Val Pro Thr Ile 
        195                 200                 205             


Ser Pro Ser Lys Ala Asn Tyr Arg Pro Gly Glu Asn Leu Asn Leu Ser 
    210                 215                 220                 


Cys His Ala Ala Ser Asn Pro Pro Ala Gln Tyr Ser Trp Phe Ile Asn 
225                 230                 235                 240 


Gly Thr Phe Gln Gln Ser Thr Gln Glu Leu Phe Ile Pro Asn Ile Thr 
                245                 250                 255     


Val Asn Asn Ser Gly Ser Tyr Met Cys Gln Ala His Asn Ser Ala Thr 
            260                 265                 270         


Gly Leu Asn Arg Thr Thr Val Thr Met Ile Thr Val Ser Gly 
        275                 280                 285     


<210>  252
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  252

Thr Asn Ile Asp Val Val Pro Phe Asn Val Ala Glu Gly Lys Glu Val 
1               5                   10                  15      


Leu Leu Val Val His Asn Glu Ser Gln Asn Leu Tyr Gly Tyr Asn Trp 
            20                  25                  30          


Tyr Lys Gly Glu Arg Val His Ala Asn Tyr Arg Ile Ile Gly Tyr Val 
        35                  40                  45              


Lys Asn Ile Ser Gln Glu Asn Ala Pro Gly Pro Ala His Asn Gly Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Pro Asn Gly Thr Leu Leu Ile Gln Asn Val Thr His 
65                  70                  75                  80  


Asn Asp Ala Gly Ile Tyr Thr Leu His Val Ile Lys Glu Asn Leu Val 
                85                  90                  95      


Asn Glu Glu Val Thr Arg Gln Phe Tyr Val Phe Ser Glu Pro Pro Lys 
            100                 105                 110         


Pro Ser Ile Thr Ser Asn Asn Phe Asn Pro Val Glu Asn Lys Asp Ile 
        115                 120                 125             


Val Val Leu Thr Cys Gln Pro Glu Thr Gln Asn Thr Thr Tyr Leu Trp 
    130                 135                 140                 


Trp Val Asn Asn Gln Ser Leu Leu Val Ser Pro Arg Leu Leu Leu Ser 
145                 150                 155                 160 


Thr Asp Asn Arg Thr Leu Val Leu Leu Ser Ala Thr Lys Asn Asp Ile 
                165                 170                 175     


Gly Pro Tyr Glu Cys Glu Ile Gln Asn Pro Val Gly Ala Ser Arg Ser 
            180                 185                 190         


Asp Pro Val Thr Leu Asn Val Arg Tyr Glu Ser Val Gln Ala Ser 
        195                 200                 205         


<210>  253
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  253

Gln Leu Thr Ile Glu Ala Val Pro Ser Asn Ala Ala Glu Gly Lys Glu 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asp Pro Arg Gly Tyr Asn 
            20                  25                  30          


Trp Tyr Lys Gly Glu Thr Val Asp Ala Asn Arg Arg Ile Ile Gly Tyr 
        35                  40                  45              


Val Ile Ser Asn Gln Gln Ile Thr Pro Gly Pro Ala Tyr Ser Asn Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Pro Asn Ala Ser Leu Leu Met Arg Asn Val Thr Arg 
65                  70                  75                  80  


Asn Asp Thr Gly Ser Tyr Thr Leu Gln Val Ile Lys Leu Asn Leu Met 
                85                  90                  95      


Ser Glu Glu Val Thr Gly Gln Phe Ser Val His Pro Glu Thr Pro Lys 
            100                 105                 110         


Pro Ser Ile Ser Ser Asn Asn Ser Asn Pro Val Glu Asp Lys Asp Ala 
        115                 120                 125             


Val Ala Phe Thr Cys Glu Pro Glu Thr Gln Asn Thr Thr Tyr Leu Trp 
    130                 135                 140                 


Trp Val Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Leu Gln Leu Ser 
145                 150                 155                 160 


Asn Gly Asn Arg Thr Leu Thr Leu Leu Ser Val Thr Arg Asn Asp Val 
                165                 170                 175     


Gly Pro Tyr Glu Cys Glu Ile Gln Asn Pro Ala Ser Ala Asn Phe Ser 
            180                 185                 190         


Asp Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Ala Pro Thr Ile 
        195                 200                 205             


Ser Pro Ser Asp Thr Tyr Tyr His Ala Gly Val Asn Leu Asn Leu Ser 
    210                 215                 220                 


Cys His Ala Ala Ser Asn Pro Pro Ser Gln Tyr Ser Trp Ser Val Asn 
225                 230                 235                 240 


Gly Thr Phe Gln Gln Tyr Thr Gln Lys Leu Phe Ile Pro Asn Ile Thr 
                245                 250                 255     


Thr Lys Asn Ser Gly Ser Tyr Ala Cys His Thr Thr Asn Ser Ala Thr 
            260                 265                 270         


Gly Arg Asn Arg Thr Thr Val Arg Met Ile Thr Val Ser Asp 
        275                 280                 285     


<210>  254
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  254

Tyr Gln Arg Glu Lys His Asn Gly Gly Arg Glu Glu Val Thr Lys Val 
1               5                   10                  15      


Ala Thr Gln Lys His Arg Gln Ser Pro Leu Asn Trp Thr Ser Ser His 
            20                  25                  30          


Phe Gly Glu Val Thr Gly Ser Ala Glu Gly Trp Gly Pro Glu Glu Pro 
        35                  40                  45              


Leu Pro Tyr Ser Arg Ala Phe Gly Glu Gly Ala Ser Ala Arg Pro Arg 
    50                  55                  60                  


Cys Cys Arg Asn Gly Gly Thr Cys Val Leu Gly Ser Phe Cys Val Cys 
65                  70                  75                  80  


Pro Ala His Phe Thr Gly Arg Tyr Cys Glu His Asp Gln Arg Arg Ser 
                85                  90                  95      


Glu Cys Gly Ala Leu Glu His Gly Ala Trp Thr Leu Arg Ala Cys His 
            100                 105                 110         


Leu Cys Arg Cys Ile Phe Gly Ala Leu His Cys Leu Pro Leu Gln Thr 
        115                 120                 125             


Pro Asp Arg Cys Asp 
    130             


<210>  255
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  255

Tyr Gln Arg Glu Lys His Asn Gly Gly Arg Glu Glu Val Thr Lys Val 
1               5                   10                  15      


Ala Thr Gln Lys His Arg Gln Ser Pro Leu Asn Trp Thr Ser Ser His 
            20                  25                  30          


Phe Gly Glu Val Thr Gly Ser Ala Glu Gly Trp Gly Pro Glu Glu Pro 
        35                  40                  45              


Leu Pro Tyr Ser Trp Ala Phe Gly Glu Gly Ala Ser Ala Arg Pro Arg 
    50                  55                  60                  


Cys Cys Arg Asn Gly Gly Thr Cys Val Leu Gly Ser Phe Cys Val Cys 
65                  70                  75                  80  


Pro Ala His Phe Thr Gly Arg Tyr Cys Glu His Asp Gln Arg Arg Ser 
                85                  90                  95      


Glu Cys Gly Ala Leu Glu His Gly Ala Trp Thr Leu Arg Ala Cys His 
            100                 105                 110         


Leu Cys Arg Cys Ile Phe Gly Ala Leu His Cys Leu Pro Leu Gln Thr 
        115                 120                 125             


Pro Asp Arg Cys Asp Pro Lys Asp Phe Leu Ala Ser His Ala His Gly 
    130                 135                 140                 


Pro Ser Ala Gly Gly Ala Pro Ser Leu Leu Leu Leu Leu Pro Cys Ala 
145                 150                 155                 160 


Leu Leu His Arg Leu Leu Arg Pro Asp Ala Pro Ala His Pro Arg Ser 
                165                 170                 175     


Leu Val Pro Ser Val Leu Gln Arg Glu Arg Arg Pro Cys Gly Arg Pro 
            180                 185                 190         


Gly Leu Gly His Arg Leu 
        195             


<210>  256
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  256

Ile Leu Gly Gly Arg Glu Ala Glu Ala His Ala Arg Pro Tyr Met Ala 
1               5                   10                  15      


Ser Val Gln Leu Asn Gly Ala His Leu Cys Gly Gly Val Leu Val Ala 
            20                  25                  30          


Glu Gln Trp Val Leu Ser Ala Ala His Cys Leu Glu Asp Ala Ala Asp 
        35                  40                  45              


Gly Lys Val Gln Val Leu Leu Gly Ala His Ser Leu Ser Gln Pro Glu 
    50                  55                  60                  


Pro Ser Lys Arg Leu Tyr Asp Val Leu Arg Ala Val Pro His Pro Asp 
65                  70                  75                  80  


Ser Gln Pro Asp Thr Ile Asp His Asp Leu Leu Leu Leu Gln Leu Ser 
                85                  90                  95      


Glu Lys Ala Thr Leu Gly Pro Ala Val Arg Pro Leu Pro Trp Gln Arg 
            100                 105                 110         


Val Asp Arg Asp Val Ala Pro Gly Thr Leu Cys Asp Val Ala Gly Trp 
        115                 120                 125             


Gly Ile Val Asn His Ala Gly Arg Arg Pro Asp Ser Leu Gln His Val 
    130                 135                 140                 


Leu Leu Pro Val Leu Asp Arg Ala Thr Cys Asn Arg Arg Thr His His 
145                 150                 155                 160 


Asp Gly Ala Ile Thr Glu Arg Leu Met Cys Ala Glu Ser Asn Arg Arg 
                165                 170                 175     


Asp Ser Cys Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Gly Gly Val 
            180                 185                 190         


Leu Glu Gly Val Val Thr Ser Gly Ser Arg Val Cys Gly Asn Arg Lys 
        195                 200                 205             


Lys Pro Gly Ile Tyr Thr Arg Val Ala Ser Tyr Ala Ala Trp Ile Asp 
    210                 215                 220                 


Ser Val Leu Ala 
225             


<210>  257
<211>  1213
<212>  PRT
<213>  Homo Sapiens

<400>  257

Glu Asp Cys Asn Glu Leu Pro Pro Arg Arg Asn Thr Glu Ile Leu Thr 
1               5                   10                  15      


Gly Ser Trp Ser Asp Gln Thr Tyr Pro Glu Gly Thr Gln Ala Ile Tyr 
            20                  25                  30          


Lys Cys Arg Pro Gly Tyr Arg Ser Leu Gly Asn Ile Ile Met Val Cys 
        35                  40                  45              


Arg Lys Gly Glu Trp Val Ala Leu Asn Pro Leu Arg Lys Cys Gln Lys 
    50                  55                  60                  


Arg Pro Cys Gly His Pro Gly Asp Thr Pro Phe Gly Thr Phe Thr Leu 
65                  70                  75                  80  


Thr Gly Gly Asn Val Phe Glu Tyr Gly Val Lys Ala Val Tyr Thr Cys 
                85                  90                  95      


Asn Glu Gly Tyr Gln Leu Leu Gly Glu Ile Asn Tyr Arg Glu Cys Asp 
            100                 105                 110         


Thr Asp Gly Trp Thr Asn Asp Ile Pro Ile Cys Glu Val Val Lys Cys 
        115                 120                 125             


Leu Pro Val Thr Ala Pro Glu Asn Gly Lys Ile Val Ser Ser Ala Met 
    130                 135                 140                 


Glu Pro Asp Arg Glu Tyr His Phe Gly Gln Ala Val Arg Phe Val Cys 
145                 150                 155                 160 


Asn Ser Gly Tyr Lys Ile Glu Gly Asp Glu Glu Met His Cys Ser Asp 
                165                 170                 175     


Asp Gly Phe Trp Ser Lys Glu Lys Pro Lys Cys Val Glu Ile Ser Cys 
            180                 185                 190         


Lys Ser Pro Asp Val Ile Asn Gly Ser Pro Ile Ser Gln Lys Ile Ile 
        195                 200                 205             


Tyr Lys Glu Asn Glu Arg Phe Gln Tyr Lys Cys Asn Met Gly Tyr Glu 
    210                 215                 220                 


Tyr Ser Glu Arg Gly Asp Ala Val Cys Thr Glu Ser Gly Trp Arg Pro 
225                 230                 235                 240 


Leu Pro Ser Cys Glu Glu Lys Ser Cys Asp Asn Pro Tyr Ile Pro Asn 
                245                 250                 255     


Gly Asp Tyr Ser Pro Leu Arg Ile Lys His Arg Thr Gly Asp Glu Ile 
            260                 265                 270         


Thr Tyr Gln Cys Arg Asn Gly Phe Tyr Pro Ala Thr Arg Gly Asn Thr 
        275                 280                 285             


Ala Lys Cys Thr Ser Thr Gly Trp Ile Pro Ala Pro Arg Cys Thr Leu 
    290                 295                 300                 


Lys Pro Cys Asp Tyr Pro Asp Ile Lys His Gly Gly Leu Tyr His Glu 
305                 310                 315                 320 


Asn Met Arg Arg Pro Tyr Phe Pro Val Ala Val Gly Lys Tyr Tyr Ser 
                325                 330                 335     


Tyr Tyr Cys Asp Glu His Phe Glu Thr Pro Ser Gly Ser Tyr Trp Asp 
            340                 345                 350         


His Ile His Cys Thr Gln Asp Gly Trp Ser Pro Ala Val Pro Cys Leu 
        355                 360                 365             


Arg Lys Cys Tyr Phe Pro Tyr Leu Glu Asn Gly Tyr Asn Gln Asn Tyr 
    370                 375                 380                 


Gly Arg Lys Phe Val Gln Gly Lys Ser Ile Asp Val Ala Cys His Pro 
385                 390                 395                 400 


Gly Tyr Ala Leu Pro Lys Ala Gln Thr Thr Val Thr Cys Met Glu Asn 
                405                 410                 415     


Gly Trp Ser Pro Thr Pro Arg Cys Ile Arg Val Lys Thr Cys Ser Lys 
            420                 425                 430         


Ser Ser Ile Asp Ile Glu Asn Gly Phe Ile Ser Glu Ser Gln Tyr Thr 
        435                 440                 445             


Tyr Ala Leu Lys Glu Lys Ala Lys Tyr Gln Cys Lys Leu Gly Tyr Val 
    450                 455                 460                 


Thr Ala Asp Gly Glu Thr Ser Gly Ser Ile Thr Cys Gly Lys Asp Gly 
465                 470                 475                 480 


Trp Ser Ala Gln Pro Thr Cys Ile Lys Ser Cys Asp Ile Pro Val Phe 
                485                 490                 495     


Met Asn Ala Arg Thr Lys Asn Asp Phe Thr Trp Phe Lys Leu Asn Asp 
            500                 505                 510         


Thr Leu Asp Tyr Glu Cys His Asp Gly Tyr Glu Ser Asn Thr Gly Ser 
        515                 520                 525             


Thr Thr Gly Ser Ile Val Cys Gly Tyr Asn Gly Trp Ser Asp Leu Pro 
    530                 535                 540                 


Ile Cys Tyr Glu Arg Glu Cys Glu Leu Pro Lys Ile Asp Val His Leu 
545                 550                 555                 560 


Val Pro Asp Arg Lys Lys Asp Gln Tyr Lys Val Gly Glu Val Leu Lys 
                565                 570                 575     


Phe Ser Cys Lys Pro Gly Phe Thr Ile Val Gly Pro Asn Ser Val Gln 
            580                 585                 590         


Cys Tyr His Phe Gly Leu Ser Pro Asp Leu Pro Ile Cys Lys Glu Gln 
        595                 600                 605             


Val Gln Ser Cys Gly Pro Pro Pro Glu Leu Leu Asn Gly Asn Val Lys 
    610                 615                 620                 


Glu Lys Thr Lys Glu Glu Tyr Gly His Ser Glu Val Val Glu Tyr Tyr 
625                 630                 635                 640 


Cys Asn Pro Arg Phe Leu Met Lys Gly Pro Asn Lys Ile Gln Cys Val 
                645                 650                 655     


Asp Gly Glu Trp Thr Thr Leu Pro Val Cys Ile Val Glu Glu Ser Thr 
            660                 665                 670         


Cys Gly Asp Ile Pro Glu Leu Glu His Gly Trp Ala Gln Leu Ser Ser 
        675                 680                 685             


Pro Pro Tyr Tyr Tyr Gly Asp Ser Val Glu Phe Asn Cys Ser Glu Ser 
    690                 695                 700                 


Phe Thr Met Ile Gly His Arg Ser Ile Thr Cys Ile His Gly Val Trp 
705                 710                 715                 720 


Thr Gln Leu Pro Gln Cys Val Ala Ile Asp Lys Leu Lys Lys Cys Lys 
                725                 730                 735     


Ser Ser Asn Leu Ile Ile Leu Glu Glu His Leu Lys Asn Lys Lys Glu 
            740                 745                 750         


Phe Asp His Asn Ser Asn Ile Arg Tyr Arg Cys Arg Gly Lys Glu Gly 
        755                 760                 765             


Trp Ile His Thr Val Cys Ile Asn Gly Arg Trp Asp Pro Glu Val Asn 
    770                 775                 780                 


Cys Ser Met Ala Gln Ile Gln Leu Cys Pro Pro Pro Pro Gln Ile Pro 
785                 790                 795                 800 


Asn Ser His Asn Met Thr Thr Thr Leu Asn Tyr Arg Asp Gly Glu Lys 
                805                 810                 815     


Val Ser Val Leu Cys Gln Glu Asn Tyr Leu Ile Gln Glu Gly Glu Glu 
            820                 825                 830         


Ile Thr Cys Lys Asp Gly Arg Trp Gln Ser Ile Pro Leu Cys Val Glu 
        835                 840                 845             


Lys Ile Pro Cys Ser Gln Pro Pro Gln Ile Glu His Gly Thr Ile Asn 
    850                 855                 860                 


Ser Ser Arg Ser Ser Gln Glu Ser Tyr Ala His Gly Thr Lys Leu Ser 
865                 870                 875                 880 


Tyr Thr Cys Glu Gly Gly Phe Arg Ile Ser Glu Glu Asn Glu Thr Thr 
                885                 890                 895     


Cys Tyr Met Gly Lys Trp Ser Ser Pro Pro Gln Cys Glu Gly Leu Pro 
            900                 905                 910         


Cys Lys Ser Pro Pro Glu Ile Ser His Gly Val Val Ala His Met Ser 
        915                 920                 925             


Asp Ser Tyr Gln Tyr Gly Glu Glu Val Thr Tyr Lys Cys Phe Glu Gly 
    930                 935                 940                 


Phe Gly Ile Asp Gly Pro Ala Ile Ala Lys Cys Leu Gly Glu Lys Trp 
945                 950                 955                 960 


Ser His Pro Pro Ser Cys Ile Lys Thr Asp Cys Leu Ser Leu Pro Ser 
                965                 970                 975     


Phe Glu Asn Ala Ile Pro Met Gly Glu Lys Lys Asp Val Tyr Lys Ala 
            980                 985                 990         


Gly Glu Gln Val Thr Tyr Thr Cys  Ala Thr Tyr Tyr Lys  Met Asp Gly 
        995                 1000                 1005             


Ala Ser  Asn Val Thr Cys Ile  Asn Ser Arg Trp Thr  Gly Arg Pro 
    1010                 1015                 1020             


Thr Cys  Arg Asp Thr Ser Cys  Val Asn Pro Pro Thr  Val Gln Asn 
    1025                 1030                 1035             


Ala Tyr  Ile Val Ser Arg Gln  Met Ser Lys Tyr Pro  Ser Gly Glu 
    1040                 1045                 1050             


Arg Val  Arg Tyr Gln Cys Arg  Ser Pro Tyr Glu Met  Phe Gly Asp 
    1055                 1060                 1065             


Glu Glu  Val Met Cys Leu Asn  Gly Asn Trp Thr Glu  Pro Pro Gln 
    1070                 1075                 1080             


Cys Lys  Asp Ser Thr Gly Lys  Cys Gly Pro Pro Pro  Pro Ile Asp 
    1085                 1090                 1095             


Asn Gly  Asp Ile Thr Ser Phe  Pro Leu Ser Val Tyr  Ala Pro Ala 
    1100                 1105                 1110             


Ser Ser  Val Glu Tyr Gln Cys  Gln Asn Leu Tyr Gln  Leu Glu Gly 
    1115                 1120                 1125             


Asn Lys  Arg Ile Thr Cys Arg  Asn Gly Gln Trp Ser  Glu Pro Pro 
    1130                 1135                 1140             


Lys Cys  Leu His Pro Cys Val  Ile Ser Arg Glu Ile  Met Glu Asn 
    1145                 1150                 1155             


Tyr Asn  Ile Ala Leu Arg Trp  Thr Ala Lys Gln Lys  Leu Tyr Ser 
    1160                 1165                 1170             


Arg Thr  Gly Glu Ser Val Glu  Phe Val Cys Lys Arg  Gly Tyr Arg 
    1175                 1180                 1185             


Leu Ser  Ser Arg Ser His Thr  Leu Arg Thr Thr Cys  Trp Asp Gly 
    1190                 1195                 1200             


Lys Leu  Glu Tyr Pro Thr Cys  Ala Lys Arg 
    1205                 1210             


<210>  258
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  258

Glu Val Lys Pro Cys Asp Phe Pro Glu Ile Gln His Gly Gly Leu Tyr 
1               5                   10                  15      


Tyr Lys Ser Leu Arg Arg Leu Tyr Phe Pro Ala Ala Ala Gly Gln Ser 
            20                  25                  30          


Tyr Ser Tyr Tyr Cys Asp Gln Asn Phe Val Thr Pro Ser Gly Ser Tyr 
        35                  40                  45              


Trp Asp Tyr Ile His Cys Thr Gln Asp Gly Trp Leu Pro Thr Val Pro 
    50                  55                  60                  


Cys Leu Arg Thr Cys Ser Lys Ser Asp Ile Glu Ile Glu Asn Gly Phe 
65                  70                  75                  80  


Ile Ser Glu Ser Ser Ser Ile Tyr Ile Leu Asn Lys Glu Ile Gln Tyr 
                85                  90                  95      


Lys Cys Lys Pro Gly Tyr Ala Thr Ala Asp Gly Asn Ser Ser Gly Ser 
            100                 105                 110         


Ile Thr Cys Leu Gln Asn Gly Trp Ser Ala Gln Pro Ile Cys Ile Lys 
        115                 120                 125             


Phe Cys Asp Met Pro Val Phe Glu Asn Ser Arg Ala Lys Ser Asn Gly 
    130                 135                 140                 


Met Arg Phe Lys Leu His Asp Thr Leu Asp Tyr Glu Cys Tyr Asp Gly 
145                 150                 155                 160 


Tyr Glu Ile Ser Tyr Gly Asn Thr Thr Gly Ser Ile Val Cys Gly Glu 
                165                 170                 175     


Asp Gly Trp Ser His Phe Pro Thr Cys Tyr Asn Ser Ser Glu Lys Cys 
            180                 185                 190         


Gly Pro Pro Pro Pro Ile Ser Asn Gly Asp Thr Thr Ser Phe Leu Leu 
        195                 200                 205             


Lys Val Tyr Val Pro Gln Ser Arg Val Glu Tyr Gln Cys Gln Ser Tyr 
    210                 215                 220                 


Tyr Glu Leu Gln Gly Ser Asn Tyr Val Thr Cys Ser Asn Gly Glu Trp 
225                 230                 235                 240 


Ser Glu Pro Pro Arg Cys Ile His Pro Cys Ile Ile Thr Glu Glu Asn 
                245                 250                 255     


Met Asn Lys Asn Asn Ile Gln Leu Lys Gly Lys Ser Asp Ile Lys Tyr 
            260                 265                 270         


Tyr Ala Lys Thr Gly Asp Thr Ile Glu Phe Met Cys Lys Leu Gly Tyr 
        275                 280                 285             


Asn Ala Asn Thr Ser Val Leu Ser Phe Gln Ala Val Cys Arg Glu Gly 
    290                 295                 300                 


Ile Val Glu Tyr Pro Arg Cys Glu 
305                 310         


<210>  259
<211>  359
<212>  PRT
<213>  Homo Sapiens

<400>  259

Lys Val Thr Tyr Thr Ser Gln Glu Asp Leu Val Glu Lys Lys Cys Leu 
1               5                   10                  15      


Ala Lys Lys Tyr Thr His Leu Ser Cys Asp Lys Val Phe Cys Gln Pro 
            20                  25                  30          


Trp Gln Arg Cys Ile Glu Gly Thr Cys Val Cys Lys Leu Pro Tyr Gln 
        35                  40                  45              


Cys Pro Lys Asn Gly Thr Ala Val Cys Ala Thr Asn Arg Arg Ser Phe 
    50                  55                  60                  


Pro Thr Tyr Cys Gln Gln Lys Ser Leu Glu Cys Leu His Pro Gly Thr 
65                  70                  75                  80  


Lys Phe Leu Asn Asn Gly Thr Cys Thr Ala Glu Gly Lys Phe Ser Val 
                85                  90                  95      


Ser Leu Lys His Gly Asn Thr Asp Ser Glu Gly Ile Val Glu Val Lys 
            100                 105                 110         


Leu Val Asp Gln Asp Lys Thr Met Phe Ile Cys Lys Ser Ser Trp Ser 
        115                 120                 125             


Met Arg Glu Ala Asn Val Ala Cys Leu Asp Leu Gly Phe Gln Gln Gly 
    130                 135                 140                 


Ala Asp Thr Gln Arg Arg Phe Lys Leu Ser Asp Leu Ser Ile Asn Ser 
145                 150                 155                 160 


Thr Glu Cys Leu His Val His Cys Arg Gly Leu Glu Thr Ser Leu Ala 
                165                 170                 175     


Glu Cys Thr Phe Thr Lys Arg Arg Thr Met Gly Tyr Gln Asp Phe Ala 
            180                 185                 190         


Asp Val Val Cys Tyr Thr Gln Lys Ala Asp Ser Pro Met Asp Asp Phe 
        195                 200                 205             


Phe Gln Cys Val Asn Gly Lys Tyr Ile Ser Gln Met Lys Ala Cys Asp 
    210                 215                 220                 


Gly Ile Asn Asp Cys Gly Asp Gln Ser Asp Glu Leu Cys Cys Lys Ala 
225                 230                 235                 240 


Cys Gln Gly Lys Gly Phe His Cys Lys Ser Gly Val Cys Ile Pro Ser 
                245                 250                 255     


Gln Tyr Gln Cys Asn Gly Glu Val Asp Cys Ile Thr Gly Glu Asp Glu 
            260                 265                 270         


Val Gly Cys Ala Gly Phe Ala Ser Val Ala Gln Glu Glu Thr Glu Ile 
        275                 280                 285             


Leu Thr Ala Asp Met Asp Ala Glu Arg Arg Arg Ile Lys Ser Leu Leu 
    290                 295                 300                 


Pro Lys Leu Ser Cys Gly Val Lys Asn Arg Met His Ile Arg Arg Lys 
305                 310                 315                 320 


Arg Ile Val Gly Gly Lys Arg Ala Gln Leu Gly Lys Met Lys Gln Ile 
                325                 330                 335     


Ser Leu Asp Ile Phe Lys Gly Leu His Arg Val Tyr Ala Ile Leu Glu 
            340                 345                 350         


Phe Cys Cys Ile Ile Leu Lys 
        355                 


<210>  260
<211>  337
<212>  PRT
<213>  Homo Sapiens

<400>  260

Cys Pro Gln Asn Cys His Cys His Ser Asp Leu Gln His Val Ile Cys 
1               5                   10                  15      


Asp Lys Val Gly Leu Gln Lys Ile Pro Lys Val Ser Glu Lys Thr Lys 
            20                  25                  30          


Leu Leu Asn Leu Gln Arg Asn Asn Phe Pro Val Leu Ala Ala Asn Ser 
        35                  40                  45              


Phe Arg Ala Met Pro Asn Leu Val Ser Leu His Leu Gln His Cys Gln 
    50                  55                  60                  


Ile Arg Glu Val Ala Ala Gly Ala Phe Arg Gly Leu Lys Gln Leu Ile 
65                  70                  75                  80  


Tyr Leu Tyr Leu Ser His Asn Asp Ile Arg Val Leu Arg Ala Gly Ala 
                85                  90                  95      


Phe Asp Asp Leu Thr Glu Leu Thr Tyr Leu Tyr Leu Asp His Asn Lys 
            100                 105                 110         


Val Thr Glu Leu Pro Arg Gly Leu Leu Ser Pro Leu Val Asn Leu Phe 
        115                 120                 125             


Ile Leu Gln Leu Asn Asn Asn Lys Ile Arg Glu Leu Arg Ala Gly Ala 
    130                 135                 140                 


Phe Gln Gly Ala Lys Asp Leu Arg Trp Leu Tyr Leu Ser Glu Asn Ala 
145                 150                 155                 160 


Leu Ser Ser Leu Gln Pro Gly Ala Leu Asp Asp Val Glu Asn Leu Ala 
                165                 170                 175     


Lys Phe His Val Asp Arg Asn Gln Leu Ser Ser Tyr Pro Ser Ala Ala 
            180                 185                 190         


Leu Ser Lys Leu Arg Val Val Glu Glu Leu Lys Leu Ser His Asn Pro 
        195                 200                 205             


Leu Lys Ser Ile Pro Asp Asn Ala Phe Gln Ser Phe Gly Arg Tyr Leu 
    210                 215                 220                 


Glu Thr Leu Trp Leu Asp Asn Thr Asn Leu Glu Lys Phe Ser Asp Gly 
225                 230                 235                 240 


Ala Phe Leu Gly Val Thr Thr Leu Lys His Val His Leu Glu Asn Asn 
                245                 250                 255     


Arg Leu Asn Gln Leu Pro Ser Asn Phe Pro Phe Asp Ser Leu Glu Thr 
            260                 265                 270         


Leu Ala Leu Thr Asn Asn Pro Trp Lys Cys Thr Cys Gln Leu Arg Gly 
        275                 280                 285             


Leu Arg Arg Trp Leu Glu Ala Lys Ala Ser Arg Pro Asp Ala Thr Cys 
    290                 295                 300                 


Ala Ser Pro Ala Lys Phe Lys Gly Gln His Ile Arg Asp Thr Asp Ala 
305                 310                 315                 320 


Phe Arg Ser Cys Lys Phe Pro Thr Lys Arg Ser Lys Lys Ala Gly Arg 
                325                 330                 335     


His 
    


<210>  261
<211>  732
<212>  PRT
<213>  Homo Sapiens

<400>  261

Gln Arg Cys Pro Gln Ala Cys Ile Cys Asp Asn Ser Arg Arg His Val 
1               5                   10                  15      


Ala Cys Arg Tyr Gln Asn Leu Thr Glu Val Pro Asp Ala Ile Pro Glu 
            20                  25                  30          


Leu Thr Gln Arg Leu Asp Leu Gln Gly Asn Leu Leu Lys Val Ile Pro 
        35                  40                  45              


Ala Ala Ala Phe Gln Gly Val Pro His Leu Thr His Leu Asp Leu Arg 
    50                  55                  60                  


His Cys Glu Val Glu Leu Val Ala Glu Gly Ala Phe Arg Gly Leu Gly 
65                  70                  75                  80  


Arg Leu Leu Leu Leu Asn Leu Ala Ser Asn His Leu Arg Glu Leu Pro 
                85                  90                  95      


Gln Glu Ala Leu Asp Gly Leu Gly Ser Leu Arg Arg Leu Glu Leu Glu 
            100                 105                 110         


Gly Asn Ala Leu Glu Glu Leu Arg Pro Gly Thr Phe Gly Ala Leu Gly 
        115                 120                 125             


Ala Leu Ala Thr Leu Asn Leu Ala His Asn Ala Leu Val Tyr Leu Pro 
    130                 135                 140                 


Ala Met Ala Phe Gln Gly Leu Leu Arg Val Arg Trp Leu Arg Leu Ser 
145                 150                 155                 160 


His Asn Ala Leu Ser Val Leu Ala Pro Glu Ala Leu Ala Gly Leu Pro 
                165                 170                 175     


Ala Leu Arg Arg Leu Ser Leu His His Asn Glu Leu Gln Ala Leu Pro 
            180                 185                 190         


Gly Pro Val Leu Ser Gln Ala Arg Gly Leu Ala Arg Leu Glu Leu Gly 
        195                 200                 205             


His Asn Pro Leu Thr Tyr Ala Gly Glu Glu Asp Gly Leu Ala Leu Pro 
    210                 215                 220                 


Gly Leu Arg Glu Leu Leu Leu Asp Gly Gly Ala Leu Gln Ala Leu Gly 
225                 230                 235                 240 


Pro Arg Ala Phe Ala His Cys Pro Arg Leu His Thr Leu Asp Leu Arg 
                245                 250                 255     


Gly Asn Gln Leu Asp Thr Leu Pro Pro Leu Gln Gly Pro Gly Gln Leu 
            260                 265                 270         


Arg Arg Leu Arg Leu Gln Gly Asn Pro Leu Trp Cys Gly Cys Gln Ala 
        275                 280                 285             


Arg Pro Leu Leu Glu Trp Leu Ala Arg Ala Arg Val Arg Ser Asp Gly 
    290                 295                 300                 


Ala Cys Gln Gly Pro Arg Arg Leu Arg Gly Glu Ala Leu Asp Ala Leu 
305                 310                 315                 320 


Arg Pro Trp Asp Leu Arg Cys Pro Gly Asp Ala Ala Gln Glu Glu Glu 
                325                 330                 335     


Glu Leu Glu Glu Arg Ala Val Ala Gly Pro Arg Ala Pro Pro Arg Gly 
            340                 345                 350         


Pro Pro Arg Gly Pro Gly Glu Glu Arg Ala Val Ala Pro Cys Pro Arg 
        355                 360                 365             


Ala Cys Val Cys Val Pro Glu Ser Arg His Ser Ser Cys Glu Gly Cys 
    370                 375                 380                 


Gly Leu Gln Ala Val Pro Arg Gly Phe Arg Ser Asp Thr Gln Leu Leu 
385                 390                 395                 400 


Asp Leu Arg Arg Asn His Phe Pro Ser Val Pro Arg Ala Ala Phe Pro 
                405                 410                 415     


Gly Leu Gly His Leu Val Ser Leu His Leu Gln His Cys Gly Ile Ala 
            420                 425                 430         


Glu Leu Glu Ala Gly Ala Leu Ala Gly Leu Gly Arg Leu Ile Tyr Leu 
        435                 440                 445             


Tyr Leu Ser Asp Asn Gln Leu Ala Gly Leu Ser Ala Ala Ala Leu Glu 
    450                 455                 460                 


Gly Ala Pro Arg Leu Gly Tyr Leu Tyr Leu Glu Arg Asn Arg Phe Leu 
465                 470                 475                 480 


Gln Val Pro Gly Ala Ala Leu Arg Ala Leu Pro Ser Leu Phe Ser Leu 
                485                 490                 495     


His Leu His Asp Asn Ala Val Asp Arg Leu Ala Pro Gly Asp Leu Gly 
            500                 505                 510         


Arg Thr Arg Ala Leu Arg Trp Val Tyr Leu Ser Gly Asn Arg Ile Thr 
        515                 520                 525             


Glu Val Ser Leu Gly Ala Leu Gly Pro Ala Arg Glu Leu Glu Lys Leu 
    530                 535                 540                 


His Leu Asp Arg Asn Gln Leu Arg Glu Val Pro Thr Gly Ala Leu Glu 
545                 550                 555                 560 


Gly Leu Pro Ala Leu Leu Glu Leu Gln Leu Ser Gly Asn Pro Leu Arg 
                565                 570                 575     


Ala Leu Arg Asp Gly Ala Phe Gln Pro Val Gly Arg Ser Leu Gln His 
            580                 585                 590         


Leu Phe Leu Asn Ser Ser Gly Leu Glu Gln Ile Cys Pro Gly Ala Phe 
        595                 600                 605             


Ser Gly Leu Gly Pro Gly Leu Gln Ser Leu His Leu Gln Lys Asn Gln 
    610                 615                 620                 


Leu Arg Ala Leu Pro Ala Leu Pro Ser Leu Ser Gln Leu Glu Leu Ile 
625                 630                 635                 640 


Asp Leu Ser Ser Asn Pro Phe His Cys Asp Cys Gln Leu Leu Pro Leu 
                645                 650                 655     


His Arg Trp Leu Thr Gly Leu Asn Leu Arg Val Gly Ala Thr Cys Ala 
            660                 665                 670         


Thr Pro Pro Asn Ala Arg Gly Gln Arg Val Lys Ala Ala Ala Ala Val 
        675                 680                 685             


Phe Glu Asp Cys Pro Gly Trp Ala Ala Arg Lys Ala Lys Arg Thr Pro 
    690                 695                 700                 


Ala Ser Arg Pro Ser Ala Arg Arg Thr Pro Ile Lys Gly Arg Gln Cys 
705                 710                 715                 720 


Gly Ala Asp Lys Val Gly Lys Glu Lys Gly Arg Leu 
                725                 730         


<210>  262
<211>  1058
<212>  PRT
<213>  Homo Sapiens

<400>  262

Ile Glu Ile Pro Ser Ser Val Gln Gln Val Pro Thr Ile Ile Lys Gln 
1               5                   10                  15      


Ser Lys Val Gln Val Ala Phe Pro Phe Asp Glu Tyr Phe Gln Ile Glu 
            20                  25                  30          


Cys Glu Ala Lys Gly Asn Pro Glu Pro Thr Phe Ser Trp Thr Lys Asp 
        35                  40                  45              


Gly Asn Pro Phe Tyr Phe Thr Asp His Arg Ile Ile Pro Ser Asn Asn 
    50                  55                  60                  


Ser Gly Thr Phe Arg Ile Pro Asn Glu Gly His Ile Ser His Phe Gln 
65                  70                  75                  80  


Gly Lys Tyr Arg Cys Phe Ala Ser Asn Lys Leu Gly Ile Ala Met Ser 
                85                  90                  95      


Glu Glu Ile Glu Phe Ile Val Pro Ser Val Pro Lys Phe Pro Lys Glu 
            100                 105                 110         


Lys Ile Asp Pro Leu Glu Val Glu Glu Gly Asp Pro Ile Val Leu Pro 
        115                 120                 125             


Cys Asn Pro Pro Lys Gly Leu Pro Pro Leu His Ile Tyr Trp Met Asn 
    130                 135                 140                 


Ile Glu Leu Glu His Ile Glu Gln Asp Glu Arg Val Tyr Met Ser Gln 
145                 150                 155                 160 


Lys Gly Asp Leu Tyr Phe Ala Asn Val Glu Glu Lys Asp Ser Arg Asn 
                165                 170                 175     


Asp Tyr Cys Cys Phe Ala Ala Phe Pro Arg Leu Arg Thr Ile Val Gln 
            180                 185                 190         


Lys Met Pro Met Lys Leu Thr Val Asn Ser Ser Asn Ser Ile Lys Gln 
        195                 200                 205             


Arg Lys Pro Lys Leu Leu Leu Pro Pro Thr Glu Ser Gly Ser Glu Ser 
    210                 215                 220                 


Ser Ile Thr Ile Leu Lys Gly Glu Ile Leu Leu Leu Glu Cys Phe Ala 
225                 230                 235                 240 


Glu Gly Leu Pro Thr Pro Gln Val Asp Trp Asn Lys Ile Gly Gly Asp 
                245                 250                 255     


Leu Pro Lys Gly Arg Glu Ala Lys Glu Asn Tyr Gly Lys Thr Leu Lys 
            260                 265                 270         


Ile Glu Asn Val Ser Tyr Gln Asp Lys Gly Asn Tyr Arg Cys Thr Ala 
        275                 280                 285             


Ser Asn Phe Leu Gly Thr Ala Thr His Asp Phe His Val Ile Val Glu 
    290                 295                 300                 


Glu Pro Pro Arg Trp Thr Lys Lys Pro Gln Ser Ala Val Tyr Ser Thr 
305                 310                 315                 320 


Gly Ser Asn Gly Ile Leu Leu Cys Glu Ala Glu Gly Glu Pro Gln Pro 
                325                 330                 335     


Thr Ile Lys Trp Arg Val Asn Gly Ser Pro Val Asp Asn His Pro Phe 
            340                 345                 350         


Ala Gly Asp Val Val Phe Pro Arg Glu Ile Ser Phe Thr Asn Leu Gln 
        355                 360                 365             


Pro Asn His Thr Ala Val Tyr Gln Cys Glu Ala Ser Asn Val His Gly 
    370                 375                 380                 


Thr Ile Leu Ala Asn Ala Asn Ile Asp Val Val Asp Val Arg Pro Leu 
385                 390                 395                 400 


Ile Gln Thr Lys Asp Gly Glu Asn Tyr Ala Thr Val Val Gly Tyr Ser 
                405                 410                 415     


Ala Phe Leu His Cys Glu Phe Phe Ala Ser Pro Glu Ala Val Val Ser 
            420                 425                 430         


Trp Gln Lys Val Glu Glu Val Lys Pro Leu Glu Gly Arg Arg Tyr His 
        435                 440                 445             


Ile Tyr Glu Asn Gly Thr Leu Gln Ile Asn Arg Thr Thr Glu Glu Asp 
    450                 455                 460                 


Ala Gly Ser Tyr Ser Cys Trp Val Glu Asn Ala Ile Gly Lys Thr Ala 
465                 470                 475                 480 


Val Thr Ala Asn Leu Asp Ile Arg Asn Ala Thr Lys Leu Arg Val Ser 
                485                 490                 495     


Pro Lys Asn Pro Arg Ile Pro Lys Leu His Met Leu Glu Leu His Cys 
            500                 505                 510         


Glu Ser Lys Cys Asp Ser His Leu Lys His Ser Leu Lys Leu Ser Trp 
        515                 520                 525             


Ser Lys Asp Gly Glu Ala Phe Glu Ile Asn Gly Thr Glu Asp Gly Arg 
    530                 535                 540                 


Ile Ile Ile Asp Gly Ala Asn Leu Thr Ile Ser Asn Val Thr Leu Glu 
545                 550                 555                 560 


Asp Gln Gly Ile Tyr Cys Cys Ser Ala His Thr Ala Leu Asp Ser Ala 
                565                 570                 575     


Ala Asp Ile Thr Gln Val Thr Val Leu Asp Val Pro Asp Pro Pro Glu 
            580                 585                 590         


Asn Leu His Leu Ser Glu Arg Gln Asn Arg Ser Val Arg Leu Thr Trp 
        595                 600                 605             


Glu Ala Gly Ala Asp His Asn Ser Asn Ile Ser Glu Tyr Ile Val Glu 
    610                 615                 620                 


Phe Glu Gly Asn Lys Glu Glu Pro Gly Arg Trp Glu Glu Leu Thr Arg 
625                 630                 635                 640 


Val Gln Gly Lys Lys Thr Thr Val Ile Leu Pro Leu Ala Pro Phe Val 
                645                 650                 655     


Arg Tyr Gln Phe Arg Val Ile Ala Val Asn Glu Val Gly Arg Ser Gln 
            660                 665                 670         


Pro Ser Gln Pro Ser Asp His His Glu Thr Pro Pro Ala Ala Pro Asp 
        675                 680                 685             


Arg Asn Pro Gln Asn Ile Arg Val Gln Ala Ser Gln Pro Lys Glu Met 
    690                 695                 700                 


Ile Ile Lys Trp Glu Pro Leu Lys Ser Met Glu Gln Asn Gly Pro Gly 
705                 710                 715                 720 


Leu Glu Tyr Arg Val Thr Trp Lys Pro Gln Gly Ala Pro Val Glu Trp 
                725                 730                 735     


Glu Glu Glu Thr Val Thr Asn His Thr Leu Arg Val Met Thr Pro Ala 
            740                 745                 750         


Val Tyr Ala Pro Tyr Asp Val Lys Val Gln Ala Ile Asn Gln Leu Gly 
        755                 760                 765             


Ser Gly Pro Asp Pro Gln Ser Val Thr Leu Tyr Ser Gly Glu Asp Tyr 
    770                 775                 780                 


Pro Asp Thr Ala Pro Val Ile His Gly Val Asp Val Ile Asn Ser Thr 
785                 790                 795                 800 


Leu Val Lys Val Thr Trp Ser Thr Val Pro Lys Asp Arg Val His Gly 
                805                 810                 815     


Arg Leu Lys Gly Tyr Gln Ile Asn Trp Trp Lys Thr Lys Ser Leu Leu 
            820                 825                 830         


Asp Gly Arg Thr His Pro Lys Glu Val Asn Ile Leu Arg Phe Ser Gly 
        835                 840                 845             


Gln Arg Asn Ser Gly Met Val Pro Ser Leu Asp Ala Phe Ser Glu Phe 
    850                 855                 860                 


His Leu Thr Val Leu Ala Tyr Asn Ser Lys Gly Ala Gly Pro Glu Ser 
865                 870                 875                 880 


Glu Pro Tyr Ile Phe Gln Thr Pro Glu Gly Val Pro Glu Gln Pro Thr 
                885                 890                 895     


Phe Leu Lys Val Ile Lys Val Asp Lys Asp Thr Ala Thr Leu Ser Trp 
            900                 905                 910         


Gly Leu Pro Lys Lys Leu Asn Gly Asn Leu Thr Gly Tyr Leu Leu Gln 
        915                 920                 925             


Tyr Gln Ile Ile Asn Asp Thr Tyr Glu Ile Gly Glu Leu Asn Asp Ile 
    930                 935                 940                 


Asn Ile Thr Thr Pro Ser Lys Pro Ser Trp His Leu Ser Asn Leu Asn 
945                 950                 955                 960 


Ala Thr Thr Lys Tyr Lys Phe Tyr Leu Arg Ala Cys Thr Ser Gln Gly 
                965                 970                 975     


Cys Gly Lys Pro Ile Thr Glu Glu Ser Ser Thr Leu Gly Glu Gly Ser 
            980                 985                 990         


Lys Gly Ile Gly Lys Ile Ser Gly  Val Asn Leu Thr Gln  Lys Thr His 
        995                 1000                 1005             


Pro Val  Glu Val Phe Glu Pro  Gly Ala Glu His Ile  Val Arg Leu 
    1010                 1015                 1020             


Met Thr  Lys Asn Trp Gly Asp  Asn Asp Ser Ile Phe  Gln Asp Val 
    1025                 1030                 1035             


Ile Glu  Thr Arg Gly Arg Glu  Tyr Ala Gly Leu Tyr  Asp Asp Ile 
    1040                 1045                 1050             


Ser Thr  Gln Gly Trp 
    1055             


<210>  263
<211>  195
<212>  PRT
<213>  Homo Sapiens

<400>  263

Arg Arg Val Val Ser Gly Gln Lys Val Cys Phe Ala Asp Phe Lys His 
1               5                   10                  15      


Pro Cys Tyr Lys Met Ala Tyr Phe His Glu Leu Ser Ser Arg Val Ser 
            20                  25                  30          


Phe Gln Glu Ala Arg Leu Ala Cys Glu Ser Glu Gly Gly Val Leu Leu 
        35                  40                  45              


Ser Leu Glu Asn Glu Ala Glu Gln Lys Leu Ile Glu Ser Met Leu Gln 
    50                  55                  60                  


Asn Leu Thr Lys Pro Gly Thr Gly Ile Ser Asp Gly Asp Phe Trp Ile 
65                  70                  75                  80  


Gly Leu Trp Arg Asn Gly Asp Gly Gln Thr Ser Gly Ala Cys Pro Asp 
                85                  90                  95      


Leu Tyr Gln Trp Ser Asp Gly Ser Asn Ser Gln Tyr Arg Asn Trp Tyr 
            100                 105                 110         


Thr Asp Glu Pro Ser Cys Gly Ser Glu Lys Cys Val Val Met Tyr His 
        115                 120                 125             


Gln Pro Thr Ala Asn Pro Gly Leu Gly Gly Pro Tyr Leu Tyr Gln Trp 
    130                 135                 140                 


Asn Asp Asp Arg Cys Asn Met Lys His Asn Tyr Ile Cys Lys Tyr Glu 
145                 150                 155                 160 


Pro Glu Ile Asn Pro Thr Ala Pro Val Glu Lys Pro Tyr Leu Thr Asn 
                165                 170                 175     


Gln Pro Gly Asp Thr His Gln Asn Val Val Val Thr Glu Ala Gly Ile 
            180                 185                 190         


Ile Pro Asn 
        195 


<210>  264
<211>  1163
<212>  PRT
<213>  Homo Sapiens

<400>  264

Arg Gln Thr Met Leu Thr Gln Ser Val Arg Arg Val Gln Pro Gly Lys 
1               5                   10                  15      


Lys Asn Pro Ser Ile Phe Ala Lys Pro Ala Asp Thr Leu Glu Ser Pro 
            20                  25                  30          


Gly Glu Trp Thr Thr Trp Phe Asn Ile Asp Tyr Pro Gly Gly Lys Gly 
        35                  40                  45              


Asp Tyr Glu Arg Leu Asp Ala Ile Arg Phe Tyr Tyr Gly Asp Arg Val 
    50                  55                  60                  


Cys Ala Arg Pro Leu Arg Leu Glu Ala Arg Thr Thr Asp Trp Thr Pro 
65                  70                  75                  80  


Ala Gly Ser Thr Gly Gln Val Val His Gly Ser Pro Arg Glu Gly Phe 
                85                  90                  95      


Trp Cys Leu Asn Arg Glu Gln Arg Pro Gly Gln Asn Cys Ser Asn Tyr 
            100                 105                 110         


Thr Val Arg Phe Leu Cys Pro Pro Gly Ser Leu Arg Arg Asp Thr Glu 
        115                 120                 125             


Arg Ile Trp Ser Pro Trp Ser Pro Trp Ser Lys Cys Ser Ala Ala Cys 
    130                 135                 140                 


Gly Gln Thr Gly Val Gln Thr Arg Thr Arg Ile Cys Leu Ala Glu Met 
145                 150                 155                 160 


Val Ser Leu Cys Ser Glu Ala Ser Glu Glu Gly Gln His Cys Met Gly 
                165                 170                 175     


Gln Asp Cys Thr Ala Cys Asp Leu Thr Cys Pro Met Gly Gln Val Asn 
            180                 185                 190         


Ala Asp Cys Asp Ala Cys Met Cys Gln Asp Phe Met Leu His Gly Ala 
        195                 200                 205             


Val Ser Leu Pro Gly Gly Ala Pro Ala Ser Gly Ala Ala Ile Tyr Leu 
    210                 215                 220                 


Leu Thr Lys Thr Pro Lys Leu Leu Thr Gln Thr Asp Ser Asp Gly Arg 
225                 230                 235                 240 


Phe Arg Ile Pro Gly Leu Cys Pro Asp Gly Lys Ser Ile Leu Lys Ile 
                245                 250                 255     


Thr Lys Val Lys Phe Ala Pro Ile Val Leu Thr Met Pro Lys Thr Ser 
            260                 265                 270         


Leu Lys Ala Ala Thr Ile Lys Ala Glu Phe Val Arg Ala Glu Thr Pro 
        275                 280                 285             


Tyr Met Val Met Asn Pro Glu Thr Lys Ala Arg Arg Ala Gly Gln Ser 
    290                 295                 300                 


Val Ser Leu Cys Cys Lys Ala Thr Gly Lys Pro Arg Pro Asp Lys Tyr 
305                 310                 315                 320 


Phe Trp Tyr His Asn Asp Thr Leu Leu Asp Pro Ser Leu Tyr Lys His 
                325                 330                 335     


Glu Ser Lys Leu Val Leu Arg Lys Leu Gln Gln His Gln Ala Gly Glu 
            340                 345                 350         


Tyr Phe Cys Lys Ala Gln Ser Asp Ala Gly Ala Val Lys Ser Lys Val 
        355                 360                 365             


Ala Gln Leu Ile Val Ile Ala Ser Asp Glu Thr Pro Cys Asn Pro Val 
    370                 375                 380                 


Pro Glu Ser Tyr Leu Ile Arg Leu Pro His Asp Cys Phe Gln Asn Ala 
385                 390                 395                 400 


Thr Asn Ser Phe Tyr Tyr Asp Val Gly Arg Cys Pro Val Lys Thr Cys 
                405                 410                 415     


Ala Gly Gln Gln Asp Asn Gly Ile Arg Cys Arg Asp Ala Val Gln Asn 
            420                 425                 430         


Cys Cys Gly Ile Ser Lys Thr Glu Glu Arg Glu Ile Gln Cys Ser Gly 
        435                 440                 445             


Tyr Thr Leu Pro Thr Lys Val Ala Lys Glu Cys Ser Cys Gln Arg Cys 
    450                 455                 460                 


Thr Glu Thr Arg Ser Ile Val Arg Gly Arg Val Ser Ala Ala Asp Asn 
465                 470                 475                 480 


Gly Glu Pro Met Arg Phe Gly His Val Tyr Met Gly Asn Ser Arg Val 
                485                 490                 495     


Ser Met Thr Gly Tyr Lys Gly Thr Phe Thr Leu His Val Pro Gln Asp 
            500                 505                 510         


Thr Glu Arg Leu Val Leu Thr Phe Val Asp Arg Leu Gln Lys Phe Val 
        515                 520                 525             


Asn Thr Thr Lys Val Leu Pro Phe Asn Lys Lys Gly Ser Ala Val Phe 
    530                 535                 540                 


His Glu Ile Lys Met Leu Arg Arg Lys Glu Pro Ile Thr Leu Glu Ala 
545                 550                 555                 560 


Met Glu Thr Asn Ile Ile Pro Leu Gly Glu Val Val Gly Glu Asp Pro 
                565                 570                 575     


Met Ala Glu Leu Glu Ile Pro Ser Arg Ser Phe Tyr Arg Gln Asn Gly 
            580                 585                 590         


Glu Pro Tyr Ile Gly Lys Val Lys Ala Ser Val Thr Phe Leu Asp Pro 
        595                 600                 605             


Arg Asn Ile Ser Thr Ala Thr Ala Ala Gln Thr Asp Leu Asn Phe Ile 
    610                 615                 620                 


Asn Asp Glu Gly Asp Thr Phe Pro Leu Arg Thr Tyr Gly Met Phe Ser 
625                 630                 635                 640 


Val Asp Phe Arg Asp Glu Val Thr Ser Glu Pro Leu Asn Ala Gly Lys 
                645                 650                 655     


Val Lys Val His Leu Asp Ser Thr Gln Val Lys Met Pro Glu His Ile 
            660                 665                 670         


Ser Thr Val Lys Leu Trp Ser Leu Asn Pro Asp Thr Gly Leu Trp Glu 
        675                 680                 685             


Glu Glu Gly Asp Phe Lys Phe Glu Asn Gln Arg Arg Asn Lys Arg Glu 
    690                 695                 700                 


Asp Arg Thr Phe Leu Val Gly Asn Leu Glu Ile Arg Glu Arg Arg Leu 
705                 710                 715                 720 


Phe Asn Leu Asp Val Pro Glu Ser Arg Arg Cys Phe Val Lys Val Arg 
                725                 730                 735     


Ala Tyr Arg Ser Glu Arg Phe Leu Pro Ser Glu Gln Ile Gln Gly Val 
            740                 745                 750         


Val Ile Ser Val Ile Asn Leu Glu Pro Arg Thr Gly Phe Leu Ser Asn 
        755                 760                 765             


Pro Arg Ala Trp Gly Arg Phe Asp Ser Val Ile Thr Gly Pro Asn Gly 
    770                 775                 780                 


Ala Cys Val Pro Ala Phe Cys Asp Asp Gln Ser Pro Asp Ala Tyr Ser 
785                 790                 795                 800 


Ala Tyr Val Leu Ala Ser Leu Ala Gly Glu Glu Leu Gln Ala Val Glu 
                805                 810                 815     


Ser Ser Pro Lys Phe Asn Pro Asn Ala Ile Gly Val Pro Gln Pro Tyr 
            820                 825                 830         


Leu Asn Lys Leu Asn Tyr Arg Arg Thr Asp His Glu Asp Pro Arg Val 
        835                 840                 845             


Lys Lys Thr Ala Phe Gln Ile Ser Met Ala Lys Pro Arg Pro Asn Ser 
    850                 855                 860                 


Ala Glu Glu Ser Asn Gly Pro Ile Tyr Ala Phe Glu Asn Leu Arg Ala 
865                 870                 875                 880 


Cys Glu Glu Ala Pro Pro Ser Ala Ala His Phe Arg Phe Tyr Gln Ile 
                885                 890                 895     


Glu Gly Asp Arg Tyr Asp Tyr Asn Thr Val Pro Phe Asn Glu Asp Asp 
            900                 905                 910         


Pro Met Ser Trp Thr Glu Asp Tyr Leu Ala Trp Trp Pro Lys Pro Met 
        915                 920                 925             


Glu Phe Arg Ala Cys Tyr Ile Lys Val Lys Ile Val Gly Pro Leu Glu 
    930                 935                 940                 


Val Asn Val Arg Ser Arg Asn Met Gly Gly Thr His Arg Arg Thr Val 
945                 950                 955                 960 


Gly Lys Leu Tyr Gly Ile Arg Asp Val Arg Ser Thr Arg Asp Arg Asp 
                965                 970                 975     


Gln Pro Asn Val Ser Ala Ala Cys Leu Glu Phe Lys Cys Ser Gly Met 
            980                 985                 990         


Leu Tyr Asp Gln Asp Arg Val Asp  Arg Thr Leu Val Lys  Val Ile Pro 
        995                 1000                 1005             


Gln Gly  Ser Cys Arg Arg Ala  Ser Val Asn Pro Met  Leu His Glu 
    1010                 1015                 1020             


Tyr Leu  Val Asn His Leu Pro  Leu Ala Val Asn Asn  Asp Thr Ser 
    1025                 1030                 1035             


Glu Tyr  Thr Met Leu Ala Pro  Leu Asp Pro Leu Gly  His Asn Tyr 
    1040                 1045                 1050             


Gly Ile  Tyr Thr Val Thr Asp  Gln Asp Pro Arg Thr  Ala Lys Glu 
    1055                 1060                 1065             


Ile Ala  Leu Gly Arg Cys Phe  Asp Gly Thr Ser Asp  Gly Ser Ser 
    1070                 1075                 1080             


Arg Ile  Met Lys Ser Asn Val  Gly Val Ala Leu Thr  Phe Asn Cys 
    1085                 1090                 1095             


Val Glu  Arg Gln Val Gly Arg  Gln Ser Ala Phe Gln  Tyr Leu Gln 
    1100                 1105                 1110             


Ser Thr  Pro Ala Gln Ser Pro  Ala Ala Gly Thr Val  Gln Gly Arg 
    1115                 1120                 1125             


Val Pro  Ser Arg Arg Gln Gln  Arg Ala Ser Arg Gly  Gly Gln Arg 
    1130                 1135                 1140             


Gln Ser  Gly Val Val Ala Ser  Leu Arg Phe Pro Arg  Val Ala Gln 
    1145                 1150                 1155             


Gln Pro  Leu Ile Asn 
    1160             


<210>  265
<211>  447
<212>  PRT
<213>  Homo Sapiens

<400>  265

Glu Glu Arg Val Phe Leu Val Gly Asn Val Glu Ile Arg Glu Arg Arg 
1               5                   10                  15      


Leu Phe Asn Leu Asp Val Pro Glu Arg Arg Arg Cys Phe Val Lys Val 
            20                  25                  30          


Arg Ala Tyr Ala Asn Asp Lys Phe Thr Pro Ser Glu Gln Val Glu Gly 
        35                  40                  45              


Val Val Val Thr Leu Val Asn Leu Glu Pro Ala Pro Gly Phe Ser Ala 
    50                  55                  60                  


Asn Pro Arg Ala Trp Gly Arg Phe Asp Ser Ala Val Thr Gly Pro Asn 
65                  70                  75                  80  


Gly Ala Cys Leu Pro Ala Phe Cys Asp Ala Asp Arg Pro Asp Ala Tyr 
                85                  90                  95      


Thr Ala Leu Val Thr Ala Thr Leu Gly Gly Glu Glu Leu Glu Pro Ala 
            100                 105                 110         


Pro Ser Leu Pro Arg Pro Leu Pro Ala Thr Val Gly Val Thr Gln Pro 
        115                 120                 125             


Tyr Leu Asp Arg Leu Gly Tyr Arg Arg Thr Asp His Asp Asp Pro Ala 
    130                 135                 140                 


Phe Lys Arg Asn Gly Phe Arg Ile Asn Leu Ala Lys Pro Arg Pro Gly 
145                 150                 155                 160 


Asp Pro Ala Glu Ala Asn Gly Pro Val Tyr Pro Trp Arg Ser Leu Arg 
                165                 170                 175     


Glu Cys Gln Gly Ala Pro Val Thr Ala Ser His Phe Arg Phe Ala Arg 
            180                 185                 190         


Val Glu Ala Asp Lys Tyr Glu Tyr Asn Val Val Pro Phe Arg Glu Gly 
        195                 200                 205             


Thr Pro Ala Ser Trp Thr Gly Asp Leu Leu Ala Trp Trp Pro Asn Pro 
    210                 215                 220                 


Gln Glu Phe Arg Ala Cys Phe Leu Lys Val Lys Ile Gln Gly Pro Gln 
225                 230                 235                 240 


Glu Tyr Met Val Arg Ser His Asn Ala Gly Gly Ser His Pro Arg Thr 
                245                 250                 255     


Arg Gly Gln Leu Tyr Gly Leu Arg Asp Ala Arg Ser Val Arg Asp Pro 
            260                 265                 270         


Glu Arg Pro Gly Thr Ser Ala Ala Cys Val Glu Phe Lys Cys Ser Gly 
        275                 280                 285             


Met Leu Phe Asp Gln Arg Gln Val Asp Arg Thr Leu Val Thr Ile Met 
    290                 295                 300                 


Pro Gln Gly Ser Cys Arg Arg Val Ala Val Asn Gly Leu Leu Arg Asp 
305                 310                 315                 320 


Tyr Leu Thr Arg His Pro Pro Pro Val Pro Ala Glu Asp Pro Ala Ala 
                325                 330                 335     


Phe Ser Met Leu Ala Pro Leu Asp Pro Leu Gly His Asn Tyr Gly Val 
            340                 345                 350         


Tyr Thr Val Thr Asp Gln Ser Pro Arg Leu Ala Lys Glu Ile Ala Ile 
        355                 360                 365             


Gly Arg Cys Phe Asp Gly Ser Ser Asp Gly Phe Ser Arg Glu Met Lys 
    370                 375                 380                 


Ala Asp Ala Gly Thr Ala Val Thr Phe Gln Cys Arg Glu Pro Pro Ala 
385                 390                 395                 400 


Gly Arg Pro Ser Leu Phe Gln Arg Leu Leu Glu Ser Pro Ala Thr Ala 
                405                 410                 415     


Leu Gly Asp Ile Arg Arg Glu Met Ser Glu Ala Ala Gln Ala Gln Ala 
            420                 425                 430         


Arg Ala Ser Gly Pro Leu Arg Thr Arg Arg Gly Arg Val Arg Gln 
        435                 440                 445         


<210>  266
<211>  870
<212>  PRT
<213>  Homo Sapiens

<400>  266

Gly Val Gln Leu Gln Asp Asn Gly Tyr Asn Gly Leu Leu Ile Ala Ile 
1               5                   10                  15      


Asn Pro Gln Val Pro Glu Asn Gln Asn Leu Ile Ser Asn Ile Lys Glu 
            20                  25                  30          


Met Ile Thr Glu Ala Ser Phe Tyr Leu Phe Asn Ala Thr Lys Arg Arg 
        35                  40                  45              


Val Phe Phe Arg Asn Ile Lys Ile Leu Ile Pro Ala Thr Trp Lys Ala 
    50                  55                  60                  


Asn Asn Asn Ser Lys Ile Lys Gln Glu Ser Tyr Glu Lys Ala Asn Val 
65                  70                  75                  80  


Ile Val Thr Asp Trp Tyr Gly Ala His Gly Asp Asp Pro Tyr Thr Leu 
                85                  90                  95      


Gln Tyr Arg Gly Cys Gly Lys Glu Gly Lys Tyr Ile His Phe Thr Pro 
            100                 105                 110         


Asn Phe Leu Leu Asn Asp Asn Leu Thr Ala Gly Tyr Gly Ser Arg Gly 
        115                 120                 125             


Arg Val Phe Val His Glu Trp Ala His Leu Arg Trp Gly Val Phe Asp 
    130                 135                 140                 


Glu Tyr Asn Asn Asp Lys Pro Phe Tyr Ile Asn Gly Gln Asn Gln Ile 
145                 150                 155                 160 


Lys Val Thr Arg Cys Ser Ser Asp Ile Thr Gly Ile Phe Val Cys Glu 
                165                 170                 175     


Lys Gly Pro Cys Pro Gln Glu Asn Cys Ile Ile Ser Lys Leu Phe Lys 
            180                 185                 190         


Glu Gly Cys Thr Phe Ile Tyr Asn Ser Thr Gln Asn Ala Thr Ala Ser 
        195                 200                 205             


Ile Met Phe Met Gln Ser Leu Ser Ser Val Val Glu Phe Cys Asn Ala 
    210                 215                 220                 


Ser Thr His Asn Gln Glu Ala Pro Asn Leu Gln Asn Gln Met Cys Ser 
225                 230                 235                 240 


Leu Arg Ser Ala Trp Asp Val Ile Thr Asp Ser Ala Asp Phe His His 
                245                 250                 255     


Ser Phe Pro Met Asn Gly Thr Glu Leu Pro Pro Pro Pro Thr Phe Ser 
            260                 265                 270         


Leu Val Gln Ala Gly Asp Lys Val Val Cys Leu Val Leu Asp Val Ser 
        275                 280                 285             


Ser Lys Met Ala Glu Ala Asp Arg Leu Leu Gln Leu Gln Gln Ala Ala 
    290                 295                 300                 


Glu Phe Tyr Leu Met Gln Ile Val Glu Ile His Thr Phe Val Gly Ile 
305                 310                 315                 320 


Ala Ser Phe Asp Ser Lys Gly Glu Ile Arg Ala Gln Leu His Gln Ile 
                325                 330                 335     


Asn Ser Asn Asp Asp Arg Lys Leu Leu Val Ser Tyr Leu Pro Thr Thr 
            340                 345                 350         


Val Ser Ala Lys Thr Asp Ile Ser Ile Cys Ser Gly Leu Lys Lys Gly 
        355                 360                 365             


Phe Glu Val Val Glu Lys Leu Asn Gly Lys Ala Tyr Gly Ser Val Met 
    370                 375                 380                 


Ile Leu Val Thr Ser Gly Asp Asp Lys Leu Leu Gly Asn Cys Leu Pro 
385                 390                 395                 400 


Thr Val Leu Ser Ser Gly Ser Thr Ile His Ser Ile Ala Leu Gly Ser 
                405                 410                 415     


Ser Ala Ala Pro Asn Leu Glu Glu Leu Ser Arg Leu Thr Gly Gly Leu 
            420                 425                 430         


Lys Phe Phe Val Pro Asp Ile Ser Asn Ser Asn Ser Met Ile Asp Ala 
        435                 440                 445             


Phe Ser Arg Ile Ser Ser Gly Thr Gly Asp Ile Phe Gln Gln His Ile 
    450                 455                 460                 


Gln Leu Glu Ser Thr Gly Glu Asn Val Lys Pro His His Gln Leu Lys 
465                 470                 475                 480 


Asn Thr Val Thr Val Asp Asn Thr Val Gly Asn Asp Thr Met Phe Leu 
                485                 490                 495     


Val Thr Trp Gln Ala Ser Gly Pro Pro Glu Ile Ile Leu Phe Asp Pro 
            500                 505                 510         


Asp Gly Arg Lys Tyr Tyr Thr Asn Asn Phe Ile Thr Asn Leu Thr Phe 
        515                 520                 525             


Arg Thr Ala Ser Leu Trp Ile Pro Gly Thr Ala Lys Pro Gly His Trp 
    530                 535                 540                 


Thr Tyr Thr Leu Asn Asn Thr His His Ser Leu Gln Ala Leu Lys Val 
545                 550                 555                 560 


Thr Val Thr Ser Arg Ala Ser Asn Ser Ala Val Pro Pro Ala Thr Val 
                565                 570                 575     


Glu Ala Phe Val Glu Arg Asp Ser Leu His Phe Pro His Pro Val Met 
            580                 585                 590         


Ile Tyr Ala Asn Val Lys Gln Gly Phe Tyr Pro Ile Leu Asn Ala Thr 
        595                 600                 605             


Val Thr Ala Thr Val Glu Pro Glu Thr Gly Asp Pro Val Thr Leu Arg 
    610                 615                 620                 


Leu Leu Asp Asp Gly Ala Gly Ala Asp Val Ile Lys Asn Asp Gly Ile 
625                 630                 635                 640 


Tyr Ser Arg Tyr Phe Phe Ser Phe Ala Ala Asn Gly Arg Tyr Ser Leu 
                645                 650                 655     


Lys Val His Val Asn His Ser Pro Ser Ile Ser Thr Pro Ala His Ser 
            660                 665                 670         


Ile Pro Gly Ser His Ala Met Tyr Val Pro Gly Tyr Thr Ala Asn Gly 
        675                 680                 685             


Asn Ile Gln Met Asn Ala Pro Arg Lys Ser Val Gly Arg Asn Glu Glu 
    690                 695                 700                 


Glu Arg Lys Trp Gly Phe Ser Arg Val Ser Ser Gly Gly Ser Phe Ser 
705                 710                 715                 720 


Val Leu Gly Val Pro Ala Gly Pro His Pro Asp Val Phe Pro Pro Cys 
                725                 730                 735     


Lys Ile Ile Asp Leu Glu Ala Val Lys Val Glu Glu Glu Leu Thr Leu 
            740                 745                 750         


Ser Trp Thr Ala Pro Gly Glu Asp Phe Asp Gln Gly Gln Ala Thr Ser 
        755                 760                 765             


Tyr Glu Ile Arg Met Ser Lys Ser Leu Gln Asn Ile Gln Asp Asp Phe 
    770                 775                 780                 


Asn Asn Ala Ile Leu Val Asn Thr Ser Lys Arg Asn Pro Gln Gln Ala 
785                 790                 795                 800 


Gly Ile Arg Glu Ile Phe Thr Phe Ser Pro Gln Ile Ser Thr Asn Gly 
                805                 810                 815     


Pro Glu His Gln Pro Asn Gly Glu Thr His Glu Ser His Arg Ile Tyr 
            820                 825                 830         


Val Ala Ile Arg Ala Met Asp Arg Asn Ser Leu Gln Ser Ala Val Ser 
        835                 840                 845             


Asn Ile Ala Gln Ala Pro Leu Phe Ile Pro Pro Asn Ser Asp Pro Val 
    850                 855                 860                 


Pro Ala Arg Asp Tyr Leu 
865                 870 


<210>  267
<211>  871
<212>  PRT
<213>  Homo Sapiens

<400>  267

Ser Phe Ile Lys Leu Asn Asn Asn Gly Phe Glu Asp Ile Val Ile Val 
1               5                   10                  15      


Ile Asp Pro Ser Val Pro Glu Asp Glu Lys Ile Ile Glu Gln Ile Glu 
            20                  25                  30          


Asp Met Val Thr Thr Ala Ser Thr Tyr Leu Phe Glu Ala Thr Glu Lys 
        35                  40                  45              


Arg Phe Phe Phe Lys Asn Val Ser Ile Leu Ile Pro Glu Asn Trp Lys 
    50                  55                  60                  


Glu Asn Pro Gln Tyr Lys Arg Pro Lys His Glu Asn His Lys His Ala 
65                  70                  75                  80  


Asp Val Ile Val Ala Pro Pro Thr Leu Pro Gly Arg Asp Glu Pro Tyr 
                85                  90                  95      


Thr Lys Gln Phe Thr Glu Cys Gly Glu Lys Gly Glu Tyr Ile His Phe 
            100                 105                 110         


Thr Pro Asp Leu Leu Leu Gly Lys Lys Gln Asn Glu Tyr Gly Pro Pro 
        115                 120                 125             


Gly Lys Leu Phe Val His Glu Trp Ala His Leu Arg Trp Gly Val Phe 
    130                 135                 140                 


Asp Glu Tyr Asn Glu Asp Gln Pro Phe Tyr Arg Ala Lys Ser Lys Lys 
145                 150                 155                 160 


Ile Glu Ala Thr Arg Cys Ser Ala Gly Ile Ser Gly Arg Asn Arg Val 
                165                 170                 175     


Tyr Lys Cys Gln Gly Gly Ser Cys Leu Ser Arg Ala Cys Arg Ile Asp 
            180                 185                 190         


Ser Thr Thr Lys Leu Tyr Gly Lys Asp Cys Gln Phe Phe Pro Asp Lys 
        195                 200                 205             


Val Gln Thr Glu Lys Ala Ser Ile Met Phe Met Gln Ser Ile Asp Ser 
    210                 215                 220                 


Val Val Glu Phe Cys Asn Glu Lys Thr His Asn Gln Glu Ala Pro Ser 
225                 230                 235                 240 


Leu Gln Asn Ile Lys Cys Asn Phe Arg Ser Thr Trp Glu Val Ile Ser 
                245                 250                 255     


Asn Ser Glu Asp Phe Lys Asn Thr Ile Pro Met Val Thr Pro Pro Pro 
            260                 265                 270         


Pro Pro Val Phe Ser Leu Leu Lys Ile Ser Gln Arg Ile Val Cys Leu 
        275                 280                 285             


Val Leu Asp Lys Ser Gly Ser Met Gly Gly Lys Asp Arg Leu Asn Arg 
    290                 295                 300                 


Met Asn Gln Ala Ala Lys His Phe Leu Leu Gln Thr Val Glu Asn Gly 
305                 310                 315                 320 


Ser Trp Val Gly Met Val His Phe Asp Ser Thr Ala Thr Ile Val Asn 
                325                 330                 335     


Lys Leu Ile Gln Ile Lys Ser Ser Asp Glu Arg Asn Thr Leu Met Ala 
            340                 345                 350         


Gly Leu Pro Thr Tyr Pro Leu Gly Gly Thr Ser Ile Cys Ser Gly Ile 
        355                 360                 365             


Lys Tyr Ala Phe Gln Val Ile Gly Glu Leu His Ser Gln Leu Asp Gly 
    370                 375                 380                 


Ser Glu Val Leu Leu Leu Thr Asp Gly Glu Asp Asn Thr Ala Ser Ser 
385                 390                 395                 400 


Cys Ile Asp Glu Val Lys Gln Ser Gly Ala Ile Val His Phe Ile Ala 
                405                 410                 415     


Leu Gly Arg Ala Ala Asp Glu Ala Val Ile Glu Met Ser Lys Ile Thr 
            420                 425                 430         


Gly Gly Ser His Phe Tyr Val Ser Asp Glu Ala Gln Asn Asn Gly Leu 
        435                 440                 445             


Ile Asp Ala Phe Gly Ala Leu Thr Ser Gly Asn Thr Asp Leu Ser Gln 
    450                 455                 460                 


Lys Ser Leu Gln Leu Glu Ser Lys Gly Leu Thr Leu Asn Ser Asn Ala 
465                 470                 475                 480 


Trp Met Asn Asp Thr Val Ile Ile Asp Ser Thr Val Gly Lys Asp Thr 
                485                 490                 495     


Phe Phe Leu Ile Thr Trp Asn Ser Leu Pro Pro Ser Ile Ser Leu Trp 
            500                 505                 510         


Asp Pro Ser Gly Thr Ile Met Glu Asn Phe Thr Val Asp Ala Thr Ser 
        515                 520                 525             


Lys Met Ala Tyr Leu Ser Ile Pro Gly Thr Ala Lys Val Gly Thr Trp 
    530                 535                 540                 


Ala Tyr Asn Leu Gln Ala Lys Ala Asn Pro Glu Thr Leu Thr Ile Thr 
545                 550                 555                 560 


Val Thr Ser Arg Ala Ala Asn Ser Ser Val Pro Pro Ile Thr Val Asn 
                565                 570                 575     


Ala Lys Met Asn Lys Asp Val Asn Ser Phe Pro Ser Pro Met Ile Val 
            580                 585                 590         


Tyr Ala Glu Ile Leu Gln Gly Tyr Val Pro Val Leu Gly Ala Asn Val 
        595                 600                 605             


Thr Ala Phe Ile Glu Ser Gln Asn Gly His Thr Glu Val Leu Glu Leu 
    610                 615                 620                 


Leu Asp Asn Gly Ala Gly Ala Asp Ser Phe Lys Asn Asp Gly Val Tyr 
625                 630                 635                 640 


Ser Arg Tyr Phe Thr Ala Tyr Thr Glu Asn Gly Arg Tyr Ser Leu Lys 
                645                 650                 655     


Val Arg Ala His Gly Gly Ala Asn Thr Ala Arg Leu Lys Leu Arg Pro 
            660                 665                 670         


Pro Leu Asn Arg Ala Ala Tyr Ile Pro Gly Trp Val Val Asn Gly Glu 
        675                 680                 685             


Ile Glu Ala Asn Pro Pro Arg Pro Glu Ile Asp Glu Asp Thr Gln Thr 
    690                 695                 700                 


Thr Leu Glu Asp Phe Ser Arg Thr Ala Ser Gly Gly Ala Phe Val Val 
705                 710                 715                 720 


Ser Gln Val Pro Ser Leu Pro Leu Pro Asp Gln Tyr Pro Pro Ser Gln 
                725                 730                 735     


Ile Thr Asp Leu Asp Ala Thr Val His Glu Asp Lys Ile Ile Leu Thr 
            740                 745                 750         


Trp Thr Ala Pro Gly Asp Asn Phe Asp Val Gly Lys Val Gln Arg Tyr 
        755                 760                 765             


Ile Ile Arg Ile Ser Ala Ser Ile Leu Asp Leu Arg Asp Ser Phe Asp 
    770                 775                 780                 


Asp Ala Leu Gln Leu Asn Thr Thr Asp Leu Ser Pro Lys Glu Ala Asn 
785                 790                 795                 800 


Ser Lys Glu Ser Phe Ala Phe Lys Pro Glu Asn Ile Ser Glu Glu Asn 
                805                 810                 815     


Ala Thr His Ile Phe Ile Ala Ile Lys Ser Ile Asp Lys Ser Asn Leu 
            820                 825                 830         


Thr Ser Lys Val Ser Asn Ile Ala Gln Val Thr Leu Phe Ile Pro Gln 
        835                 840                 845             


Ala Asn Pro Asp Asp Ile Asp Pro Thr Pro Thr Pro Thr Pro Thr Pro 
    850                 855                 860                 


Asp Lys Ser His Asn Ser Gly 
865                 870     


<210>  268
<211>  177
<212>  PRT
<213>  Homo Sapiens

<400>  268

Cys Leu Val Thr His His Asn Phe Ser Arg Cys Lys Arg Gly Thr Gly 
1               5                   10                  15      


Val His Lys Leu Glu His His Ala Lys Leu Lys Cys Ile Lys Glu Lys 
            20                  25                  30          


Ser Glu Leu Lys Ser Ala Glu Gly Ser Thr Trp Asn Cys Cys Pro Ile 
        35                  40                  45              


Asp Trp Arg Ala Phe Gln Ser Asn Cys Tyr Phe Pro Leu Thr Asp Asn 
    50                  55                  60                  


Lys Thr Trp Ala Glu Ser Glu Arg Asn Cys Ser Gly Met Gly Ala His 
65                  70                  75                  80  


Leu Met Thr Ile Ser Thr Glu Ala Glu Gln Asn Phe Ile Ile Gln Phe 
                85                  90                  95      


Leu Asp Arg Arg Leu Ser Tyr Phe Leu Gly Leu Arg Asp Glu Asn Ala 
            100                 105                 110         


Lys Gly Gln Trp Arg Trp Val Asp Gln Thr Pro Phe Asn Pro Arg Arg 
        115                 120                 125             


Val Phe Trp His Lys Asn Glu Pro Asp Asn Ser Gln Gly Glu Asn Cys 
    130                 135                 140                 


Val Val Leu Val Tyr Asn Gln Asp Lys Trp Ala Trp Asn Asp Val Pro 
145                 150                 155                 160 


Cys Asn Phe Glu Ala Ser Arg Ile Cys Lys Ile Pro Gly Thr Thr Leu 
                165                 170                 175     


Asn 
    


<210>  269
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  269

Gln Asn Ser Lys Phe Gln Arg Asp Leu Val Thr Leu Arg Thr Asp Phe 
1               5                   10                  15      


Ser Asn Phe Thr Ser Asn Thr Val Ala Glu Ile Gln Ala Leu Thr Ser 
            20                  25                  30          


Gln Gly Ser Ser Leu Glu Glu Thr Ile Ala Ser Leu Lys Ala Glu Val 
        35                  40                  45              


Glu Gly Phe Lys Gln Glu Arg Gln Ala Gly Val Ser Glu Leu Gln Glu 
    50                  55                  60                  


His Thr Thr Gln Lys Ala His Leu Gly His Cys Pro His Cys Pro Ser 
65                  70                  75                  80  


Val Cys Val Pro Val His Ser Glu Met Leu Leu Arg Val Gln Gln Leu 
                85                  90                  95      


Val Gln Asp Leu Lys Lys Leu Thr Cys Gln Val Ala Thr Leu Asn Asn 
            100                 105                 110         


Asn Ala Ser Thr Glu Gly Thr Cys Cys Pro Val Asn Trp Val Glu His 
        115                 120                 125             


Gln Asp Ser Cys Tyr Trp Phe Ser His Ser Gly Met Ser Trp Ala Glu 
    130                 135                 140                 


Ala Glu Lys Tyr Cys Gln Leu Lys Asn Ala His Leu Val Val Ile Asn 
145                 150                 155                 160 


Ser Arg Glu Glu Gln Asn Phe Val Gln Lys Tyr Leu Gly Ser Ala Tyr 
                165                 170                 175     


Thr Trp Met Gly Leu Ser Asp Pro Glu Gly Ala Trp Lys Trp Val Asp 
            180                 185                 190         


Gly Thr Asp Tyr Ala Thr Gly Phe Gln Asn Trp Lys Pro Gly Gln Pro 
        195                 200                 205             


Asp Asp Trp Gln Gly His Gly Leu Gly Gly Gly Glu Asp Cys Ala His 
    210                 215                 220                 


Phe His Pro Asp Gly Arg Trp Asn Asp Asp Val Cys Gln Arg Pro Tyr 
225                 230                 235                 240 


His Trp Val Cys Glu Ala Gly Leu Gly Gln Thr Ser Gln Glu Ser His 
                245                 250                 255     


<210>  270
<211>  302
<212>  PRT
<213>  Homo Sapiens

<400>  270

Ala Arg Gly Ala Glu Arg Glu Trp Glu Gly Gly Trp Gly Gly Ala Gln 
1               5                   10                  15      


Glu Glu Glu Arg Glu Arg Glu Ala Leu Met Leu Lys His Leu Gln Glu 
            20                  25                  30          


Ala Leu Gly Leu Pro Ala Gly Arg Gly Asp Glu Asn Pro Ala Gly Thr 
        35                  40                  45              


Val Glu Gly Lys Glu Asp Trp Glu Met Glu Glu Asp Gln Gly Glu Glu 
    50                  55                  60                  


Glu Glu Glu Glu Ala Thr Pro Thr Pro Ser Ser Gly Pro Ser Pro Ser 
65                  70                  75                  80  


Pro Thr Pro Glu Asp Ile Val Thr Tyr Ile Leu Gly Arg Leu Ala Gly 
                85                  90                  95      


Leu Asp Ala Gly Leu His Gln Leu His Val Arg Leu His Ala Leu Asp 
            100                 105                 110         


Thr Arg Val Val Glu Leu Thr Gln Gly Leu Arg Gln Leu Arg Asn Ala 
        115                 120                 125             


Ala Gly Asp Thr Arg Asp Ala Val Gln Ala Leu Gln Glu Ala Gln Gly 
    130                 135                 140                 


Arg Ala Glu Arg Glu His Gly Arg Leu Glu Gly Cys Leu Lys Gly Leu 
145                 150                 155                 160 


Arg Leu Gly His Lys Cys Phe Leu Leu Ser Arg Asp Phe Glu Ala Gln 
                165                 170                 175     


Ala Ala Ala Gln Ala Arg Cys Thr Ala Arg Gly Gly Ser Leu Ala Gln 
            180                 185                 190         


Pro Ala Asp Arg Gln Gln Met Glu Ala Leu Thr Arg Tyr Leu Arg Ala 
        195                 200                 205             


Ala Leu Ala Pro Tyr Asn Trp Pro Val Trp Leu Gly Val His Asp Arg 
    210                 215                 220                 


Arg Ala Glu Gly Leu Tyr Leu Phe Glu Asn Gly Gln Arg Val Ser Phe 
225                 230                 235                 240 


Phe Ala Trp His Arg Ser Pro Arg Pro Glu Leu Gly Ala Gln Pro Ser 
                245                 250                 255     


Ala Ser Pro His Pro Leu Ser Pro Asp Gln Pro Asn Gly Gly Thr Leu 
            260                 265                 270         


Glu Asn Cys Val Ala Gln Ala Ser Asp Asp Gly Ser Trp Trp Asp His 
        275                 280                 285             


Asp Cys Gln Arg Arg Leu Tyr Tyr Val Cys Glu Phe Pro Phe 
    290                 295                 300         


<210>  271
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  271

His Val Thr Leu Lys Ile Glu Met Lys Lys Met Asn Lys Leu Gln Asn 
1               5                   10                  15      


Ile Ser Glu Glu Leu Gln Arg Asn Ile Ser Leu Gln Leu Met Ser Asn 
            20                  25                  30          


Met Asn Ile Ser Asn Lys Ile Arg Asn Leu Ser Thr Thr Leu Gln Thr 
        35                  40                  45              


Ile Ala Thr Lys Leu Cys Arg Glu Leu Tyr Ser Lys Glu Gln Glu His 
    50                  55                  60                  


Lys Cys Lys Pro Cys Pro Arg Arg Trp Ile Trp His Lys Asp Ser Cys 
65                  70                  75                  80  


Tyr Phe Leu Ser Asp Asp Val Gln Thr Trp Gln Glu Ser Lys Met Ala 
                85                  90                  95      


Cys Ala Ala Gln Asn Ala Ser Leu Leu Lys Ile Asn Asn Lys Asn Ala 
            100                 105                 110         


Leu Glu Phe Ile Lys Ser Gln Ser Arg Ser Tyr Asp Tyr Trp Leu Gly 
        115                 120                 125             


Leu Ser Pro Glu Glu Asp Ser Thr Arg Gly Met Arg Val Asp Asn Ile 
    130                 135                 140                 


Ile Asn Ser Ser Ala Trp Val Ile Arg Asn Ala Pro Asp Leu Asn Asn 
145                 150                 155                 160 


Met Tyr Cys Gly Tyr Ile Asn Arg Leu Tyr Val Gln Tyr Tyr His Cys 
                165                 170                 175     


Thr Tyr Lys Gln Arg Met Ile Cys Glu Lys Met Ala Asn Pro Val Gln 
            180                 185                 190         


Leu Gly Ser Thr Tyr Phe Arg Glu Ala 
        195                 200     


<210>  272
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  272

Leu Gln Ile Ser Asn Asp Ile Asn Ser Asp Ser Glu Lys Leu Ser Gln 
1               5                   10                  15      


Leu Gln Lys Thr Ile Gln Gln Gln Gln Asp Asn Leu Ser Gln Gln Leu 
            20                  25                  30          


Gly Asn Ser Asn Asn Leu Ser Met Glu Glu Glu Phe Leu Lys Ser Gln 
        35                  40                  45              


Ile Ser Ser Leu Leu Lys Arg Gln Glu Gln Met Ala Ile Lys Leu Cys 
    50                  55                  60                  


Gln Glu Leu Ile Ile His Thr Ser Asp His Arg Cys Asn Pro Cys Pro 
65                  70                  75                  80  


Lys Met Trp Gln Trp Tyr Gln Asn Ser Cys Tyr Tyr Phe Thr Thr Asn 
                85                  90                  95      


Glu Glu Lys Thr Trp Ala Asn Ser Arg Lys Asp Cys Ile Asp Lys Asn 
            100                 105                 110         


Ser Thr Leu Val Lys Ile Asp Ser Leu Glu Glu Lys Asp Phe Leu Met 
        115                 120                 125             


Ser Gln Pro Leu Leu Met Phe Ser Phe Phe Trp Leu Gly Leu Ser Trp 
    130                 135                 140                 


Asp Ser Ser Gly Arg Ser Trp Phe Trp Glu Asp Gly Ser Val Pro Ser 
145                 150                 155                 160 


Pro Ser Leu Tyr Val Ser Asn Tyr 
                165             


<210>  273
<211>  353
<212>  PRT
<213>  Homo Sapiens

<400>  273

Met Lys Arg Gln Ala Ala Glu Glu Ala Cys Ile Leu Arg Gly Gly Ala 
1               5                   10                  15      


Leu Ser Thr Val Arg Ala Gly Ala Glu Leu Arg Ala Val Leu Ala Leu 
            20                  25                  30          


Leu Arg Ala Gly Pro Gly Pro Gly Gly Gly Ser Lys Asp Leu Leu Phe 
        35                  40                  45              


Trp Val Ala Leu Glu Arg Arg Arg Ser His Cys Thr Leu Glu Asn Glu 
    50                  55                  60                  


Pro Leu Arg Gly Phe Ser Trp Leu Ser Ser Asp Pro Gly Gly Leu Glu 
65                  70                  75                  80  


Ser Asp Thr Leu Gln Trp Val Glu Glu Pro Gln Arg Ser Cys Thr Ala 
                85                  90                  95      


Arg Arg Cys Ala Val Leu Gln Ala Thr Gly Gly Val Glu Pro Ala Gly 
            100                 105                 110         


Trp Lys Glu Met Arg Cys His Leu Arg Ala Asn Gly Tyr Leu Cys Lys 
        115                 120                 125             


Tyr Gln Phe Glu Val Leu Cys Pro Ala Pro Arg Pro Gly Ala Ala Ser 
    130                 135                 140                 


Asn Leu Ser Tyr Arg Ala Pro Phe Gln Leu His Ser Ala Ala Leu Asp 
145                 150                 155                 160 


Phe Ser Pro Pro Gly Thr Glu Val Ser Ala Leu Cys Arg Gly Gln Leu 
                165                 170                 175     


Pro Ile Ser Val Thr Cys Ile Ala Asp Glu Ile Gly Ala Arg Trp Asp 
            180                 185                 190         


Lys Leu Ser Gly Asp Val Leu Cys Pro Cys Pro Gly Arg Tyr Leu Arg 
        195                 200                 205             


Ala Gly Lys Cys Ala Glu Leu Pro Asn Cys Leu Asp Asp Leu Gly Gly 
    210                 215                 220                 


Phe Ala Cys Glu Cys Ala Thr Gly Phe Glu Leu Gly Lys Asp Gly Arg 
225                 230                 235                 240 


Ser Cys Val Thr Ser Gly Glu Gly Gln Pro Thr Leu Gly Gly Thr Gly 
                245                 250                 255     


Val Pro Thr Arg Arg Pro Pro Ala Thr Ala Thr Ser Pro Val Pro Gln 
            260                 265                 270         


Arg Thr Trp Pro Ile Arg Val Asp Glu Lys Leu Gly Glu Thr Pro Leu 
        275                 280                 285             


Val Pro Glu Gln Asp Asn Ser Val Thr Ser Ile Pro Glu Ile Pro Arg 
    290                 295                 300                 


Trp Gly Ser Gln Ser Thr Met Ser Thr Leu Gln Met Ser Leu Gln Ala 
305                 310                 315                 320 


Glu Ser Lys Ala Thr Ile Thr Pro Ser Gly Ser Val Ile Ser Lys Phe 
                325                 330                 335     


Asn Ser Thr Thr Ser Ser Ala Thr Pro Gln Ala Phe Asp Ser Ser Ser 
            340                 345                 350         


Ala 
    


<210>  274
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  274

Lys Tyr Gln Glu Leu Met Glu Glu Leu Arg Met Leu Ser Phe Gln Gln 
1               5                   10                  15      


Met Thr Trp Arg Thr Asn Met Thr Gly Met Ala Gly Leu Ala Gly Leu 
            20                  25                  30          


Lys His Asp Ile Ala Arg Val Arg Ala Asp Thr Asn Gln Ser Leu Val 
        35                  40                  45              


Glu Leu Trp Gly Leu Leu Asp Cys Arg Arg Ile Thr Cys Pro Glu Gly 
    50                  55                  60                  


Trp Leu Pro Phe Glu Gly Lys Cys Tyr Tyr Phe Ser Pro Ser Thr Lys 
65                  70                  75                  80  


Ser Trp Asp Glu Ala Arg Met Phe Cys Gln Glu Asn Tyr Ser His Leu 
                85                  90                  95      


Val Ile Ile Asn Ser Phe Ala Glu His Asn Phe Val Ala Lys Ala His 
            100                 105                 110         


Gly Ser Pro Arg Val Tyr Trp Leu Gly Leu Asn Asp Arg Ala Gln Glu 
        115                 120                 125             


Gly Asp Trp Arg Trp Leu Asp Gly Ser Pro Val Thr Leu Ser Phe Trp 
    130                 135                 140                 


Glu Pro Glu Glu Pro Asn Asn Ile His Asp Glu Asp Cys Ala Thr Met 
145                 150                 155                 160 


Asn Lys Gly Gly Thr Trp Asn Asp Leu Ser Cys Tyr Lys Thr Thr Tyr 
                165                 170                 175     


Trp Ile Cys Glu Arg Lys Cys Ser Cys 
            180                 185 


<210>  275
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  275

Glu Val Trp Pro Pro Gln Leu Gln Glu Gln Ala Pro Met Ala Gly Ala 
1               5                   10                  15      


Leu Asn Arg Lys Glu Ser Phe Leu Leu Leu Ser Leu His Asn Arg Leu 
            20                  25                  30          


Arg Ser Trp Val Gln Pro Pro Ala Ala Asp Met Arg Arg Leu Asp Trp 
        35                  40                  45              


Ser Asp Ser Leu Ala Gln Leu Ala Gln Ala Arg Ala Ala Leu Cys Gly 
    50                  55                  60                  


Thr Pro Thr Pro Ser Leu Ala Ser Gly Leu Trp Arg Thr Leu Gln Val 
65                  70                  75                  80  


Gly Trp Asn Met Gln Leu Leu Pro Ala Gly Leu Val Ser Phe Val Glu 
                85                  90                  95      


Val Val Ser Leu Trp Phe Ala Glu Gly Gln Arg Tyr Ser His Ala Ala 
            100                 105                 110         


Gly Glu Cys Ala Arg Asn Ala Thr Cys Thr His Tyr Thr Gln Leu Val 
        115                 120                 125             


Trp Ala Thr Ser Ser Gln Leu Gly Cys Gly Arg His Leu Cys Ser Ala 
    130                 135                 140                 


Gly Gln Ala Ala Ile Glu Ala Phe Val Cys Ala Tyr Ser Pro Arg Gly 
145                 150                 155                 160 


Asn Trp Glu Val Asn Gly Lys Thr Ile Val Pro Tyr Lys Lys Gly Ala 
                165                 170                 175     


Trp Cys Ser Leu Cys Thr Ala Ser Val Ser Gly Cys Phe Lys Ala Trp 
            180                 185                 190         


Asp His Ala Gly Gly Leu Cys Glu Val Pro Arg Asn Pro Cys Arg Met 
        195                 200                 205             


Ser Cys Gln Asn His Gly Arg Leu Asn Ile Ser Thr Cys His Cys His 
    210                 215                 220                 


Cys Pro Pro Gly Tyr Thr Gly Arg Tyr Cys Gln Val Arg Cys Ser Leu 
225                 230                 235                 240 


Gln Cys Val His Gly Arg Leu Arg Glu Glu Glu Cys Ser Cys Val Cys 
                245                 250                 255     


Asp Ile Gly Tyr Gly Gly Ala Gln Cys Ala Thr Lys Val His Phe Pro 
            260                 265                 270         


Phe His Thr Cys Asp Leu Arg Ile Asp Gly Asp Cys Phe Met Val Ser 
        275                 280                 285             


Ser Glu Ala Asp Thr Tyr Tyr Arg Ala Arg Met Lys Cys Gln Arg Lys 
    290                 295                 300                 


Gly Gly Val Leu Ala Gln Ile Lys Ser Gln Lys Val Gln Asp Ile Leu 
305                 310                 315                 320 


Ala Phe Tyr Leu Gly Arg Leu Glu Thr Thr Asn Glu Val Ile Asp Ser 
                325                 330                 335     


Asp Phe Glu Thr Arg Asn Phe Trp Ile Gly Leu Thr Tyr Lys Thr Ala 
            340                 345                 350         


Lys Asp Ser Phe Arg Trp Ala Thr Gly Glu His Gln Ala Phe Thr Ser 
        355                 360                 365             


Phe Ala Phe Gly Gln Pro Asp Asn His Gly Phe Gly Asn Cys Val Glu 
    370                 375                 380                 


Leu Gln Ala Ser Ala Ala Phe Asn Trp Asn Asn Gln Arg Cys Lys Thr 
385                 390                 395                 400 


Arg Asn Arg Tyr Ile Cys Gln Phe Ala Gln Glu His Ile Ser Arg Trp 
                405                 410                 415     


Gly Pro Gly Ser 
            420 


<210>  276
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  276

Glu Val Trp Pro Pro Gln Leu Gln Glu Gln Ala Pro Met Ala Gly Ala 
1               5                   10                  15      


Leu Asn Arg Lys Glu Ser Phe Leu Leu Leu Ser Leu His Asn Arg Leu 
            20                  25                  30          


Arg Ser Trp Val Gln Pro Pro Ala Ala Asp Met Arg Arg Leu Asp Trp 
        35                  40                  45              


Ser Asp Ser Leu Ala Gln Leu Ala Gln Ala Arg Ala Ala Leu Cys Gly 
    50                  55                  60                  


Thr Pro Thr Pro Ser Leu Ala Ser Gly Leu Trp Arg Thr Leu Gln Val 
65                  70                  75                  80  


Gly Trp Asn Met Gln Leu Leu Pro Ala Gly Leu Ala Ser Phe Val Glu 
                85                  90                  95      


Val Val Ser Leu Trp Phe Ala Glu Gly Gln Arg Tyr Ser His Ala Ala 
            100                 105                 110         


Gly Glu Cys Ala Arg Asn Ala Thr Cys Thr His Tyr Met Gln Leu Val 
        115                 120                 125             


Trp Ala Thr Ser Ser Gln Leu Gly Cys Gly Arg His Leu Cys Ser Ala 
    130                 135                 140                 


Gly Gln Ala Ala Ile Glu Ala Phe Val Cys Ala Tyr Ser Pro Arg Gly 
145                 150                 155                 160 


Asn Trp Glu Val Asn Gly Lys Thr Ile Val Pro Tyr Lys Lys Gly Ala 
                165                 170                 175     


Trp Cys Ser Leu Cys Thr Ala Ser Val Ser Gly Cys Phe Lys Ala Trp 
            180                 185                 190         


Asp His Ala Gly Gly Leu Cys Glu Val Pro Arg Asn Pro Cys Arg Met 
        195                 200                 205             


Ser Cys Gln Asn His Gly Arg Leu Asn Ile Ser Thr Cys His Cys His 
    210                 215                 220                 


Cys Pro Pro Gly Tyr Thr Gly Arg Tyr Cys Gln Val Arg Cys Ser Leu 
225                 230                 235                 240 


Gln Cys Val His Gly Arg Phe Arg Glu Glu Glu Cys Ser Cys Val Cys 
                245                 250                 255     


Asp Ile Gly Tyr Gly Gly Ala Gln Cys Ala Thr Lys Val His Phe Pro 
            260                 265                 270         


Phe His Thr Cys Asp Leu Arg Ile Asp Gly Asp Cys Phe Met Val Ser 
        275                 280                 285             


Ser Glu Ala Asp Thr Tyr Tyr Arg Ala Arg Met Lys Cys Gln Arg Lys 
    290                 295                 300                 


Gly Gly Val Leu Ala Gln Ile Lys Arg Gln Lys Val Gln Asp Ile Leu 
305                 310                 315                 320 


Ala Phe Tyr Leu Gly Arg Leu Glu Thr Thr Asn Glu Val Ile Asp Ser 
                325                 330                 335     


Asp Phe Glu Thr Arg Asn Phe Trp Ile Gly Leu Thr Tyr Lys Thr Ala 
            340                 345                 350         


Lys Asp Ser Phe Arg Trp Ala Thr Gly Glu His Gln Ala Phe Thr Ser 
        355                 360                 365             


Phe Ala Phe Gly Gln Pro Asp Asn His Gly Phe Gly Asn Cys Val Glu 
    370                 375                 380                 


Leu Gln Ala Ser Ala Ala Phe Asn Trp Asn Asp Gln Arg Cys Lys Thr 
385                 390                 395                 400 


Arg Asn Arg Tyr Ile Cys Gln Phe Ala Gln Glu His Ile Ser Arg Trp 
                405                 410                 415     


Gly Pro Gly Ser 
            420 


<210>  277
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  277

Phe Pro Gln Thr Asp Ile Ser Ile Ser Pro Ala Leu Pro Glu Leu Pro 
1               5                   10                  15      


Leu Pro Ser Leu Cys Pro Leu Phe Trp Met Glu Phe Lys Gly His Cys 
            20                  25                  30          


Tyr Arg Phe Phe Pro Leu Asn Lys Thr Trp Ala Glu Ala Asp Leu Tyr 
        35                  40                  45              


Cys Ser Glu Phe Ser Val Gly Arg Lys Ser Ala Lys Leu Ala Ser Ile 
    50                  55                  60                  


His Ser Trp Glu Glu Asn Val Phe Val Tyr Asp Leu Val Asn Ser Cys 
65                  70                  75                  80  


Val Pro Gly Ile Pro Ala Asp Val Trp Thr Gly Leu His Asp His Arg 
                85                  90                  95      


Gln Val Arg Lys Gln Trp Pro Leu Gly Pro Leu Gly Ser Ser Ser Gln 
            100                 105                 110         


Asp Ser Ile Leu Ile 
        115         


<210>  278
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  278

Gln Tyr Tyr Gln Leu Ser Asn Thr Gly Gln Asp Thr Ile Ser Gln Met 
1               5                   10                  15      


Glu Glu Arg Leu Gly Asn Thr Ser Gln Glu Leu Gln Ser Leu Gln Val 
            20                  25                  30          


Gln Asn Ile Lys Leu Ala Gly Ser Leu Gln His Val Ala Glu Lys Leu 
        35                  40                  45              


Cys Arg Glu Leu Tyr Asn Lys Ala Gly Ala His Arg Cys Ser Pro Cys 
    50                  55                  60                  


Thr Glu Gln Trp Lys Trp His Gly Asp Asn Cys Tyr Gln Phe Tyr Lys 
65                  70                  75                  80  


Asp Ser Lys Ser Trp Glu Asp Cys Lys Tyr Phe Cys Leu Ser Glu Asn 
                85                  90                  95      


Ser Thr Met Leu Lys Ile Asn Lys Gln Glu Asp Leu Glu Phe Ala Ala 
            100                 105                 110         


Ser Gln Ser Tyr Ser Glu Phe Phe Tyr Ser Tyr Trp Thr Gly Leu Leu 
        115                 120                 125             


Arg Pro Asp Ser Gly Lys Ala Trp Leu Trp Met Asp Gly Thr Pro Phe 
    130                 135                 140                 


Thr Ser Glu Leu Phe His Ile Ile Ile Asp Val Thr Ser Pro Arg Ser 
145                 150                 155                 160 


Arg Asp Cys Val Ala Ile Leu Asn Gly Met Ile Phe Ser Lys Asp Cys 
                165                 170                 175     


Lys Glu Leu Lys Arg Cys Val Cys Glu Arg Arg Ala Gly Met Val Lys 
            180                 185                 190         


Pro Glu Ser Leu His Val Pro Pro Glu Thr Leu Gly Glu Gly Asp 
        195                 200                 205         


<210>  279
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  279

Ala Val Met Gln Arg Asn Tyr Leu Gln Asp Glu Asn Glu Asn Arg Thr 
1               5                   10                  15      


Gly Thr Leu Gln Gln Leu Ala Lys Arg Phe Cys Gln Tyr Val Val Lys 
            20                  25                  30          


Gln Ser Glu Leu Lys Gly Thr Phe Lys Gly His Lys Cys Ser Pro Cys 
        35                  40                  45              


Asp Thr Asn Trp Arg Tyr Tyr Gly Asp Ser Cys Tyr Gly Phe Phe Arg 
    50                  55                  60                  


His Asn Leu Thr Trp Glu Glu Ser Lys Gln Tyr Cys Thr Asp Met Asn 
65                  70                  75                  80  


Ala Thr Leu Leu Lys Ile Asp Asn Arg Asn Ile Val Glu Tyr Ile Lys 
                85                  90                  95      


Ala Arg Thr His Leu Ile Arg Trp Val Gly Leu Ser Arg Gln Lys Ser 
            100                 105                 110         


Asn Glu Val Trp Lys Trp Glu Asp Gly Ser Val Ile Ser Glu Asn Met 
        115                 120                 125             


Phe Glu Phe Leu Glu Asp Gly Lys Gly Asn Met Asn Cys Ala Tyr Phe 
    130                 135                 140                 


His Asn Gly Lys Met His Pro Thr Phe Cys Glu Asn Lys His Tyr Leu 
145                 150                 155                 160 


Met Cys Glu Arg Lys Ala Gly Met Thr Lys Val Asp Gln Leu Pro 
                165                 170                 175 


<210>  280
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  280

Lys Leu Thr Arg Asp Ser Gln Ser Leu Cys Pro Tyr Asp Trp Ile Gly 
1               5                   10                  15      


Phe Gln Asn Lys Cys Tyr Tyr Phe Ser Lys Glu Glu Gly Asp Trp Asn 
            20                  25                  30          


Ser Ser Lys Tyr Asn Cys Ser Thr Gln His Ala Asp Leu Thr Ile Ile 
        35                  40                  45              


Asp Asn Ile Glu Glu Thr Asn Phe Leu Arg Arg Tyr Lys Cys Ser Ser 
    50                  55                  60                  


Asp His Trp Ile Gly Leu Lys Met Ala Lys Asn Arg Thr Gly Gln Trp 
65                  70                  75                  80  


Val Asp Gly Ala Thr Phe Thr Lys Ser Phe Gly Met Arg Gly Ser Glu 
                85                  90                  95      


Gly Cys Ala Tyr Leu Ser Asp Asp Gly Ala Ala Thr Ala Arg Cys Tyr 
            100                 105                 110         


Thr Glu Arg Lys Trp Ile Cys Arg Lys Arg Ile His 
        115                 120                 


<210>  281
<211>  95
<212>  PRT
<213>  Homo Sapiens

<400>  281

Arg Ala Asn Cys His Gln Glu Pro Ser Val Cys Leu Gln Ala Ala Cys 
1               5                   10                  15      


Pro Glu Ser Trp Ile Gly Phe Gln Arg Lys Cys Phe Tyr Phe Ser Asp 
            20                  25                  30          


Asp Thr Lys Asn Trp Thr Ser Ser Gln Arg Phe Cys Asp Ser Gln Asp 
        35                  40                  45              


Ala Asp Leu Ala Gln Val Glu Ser Phe Gln Glu Leu Asn Phe Leu Leu 
    50                  55                  60                  


Arg Tyr Lys Gly Pro Ser Asp His Trp Ile Gly Leu Ser Arg Glu Gln 
65                  70                  75                  80  


Gly Gln Pro Trp Lys Trp Ile Asn Gly Thr Glu Trp Thr Arg Gln 
                85                  90                  95  


<210>  282
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  282

His Thr Ser Arg Leu Lys Ala Arg Lys His Ser Lys Arg Arg Val Arg 
1               5                   10                  15      


Asp Lys Asp Gly Asp Leu Lys Thr Gln Ile Glu Lys Leu Trp Thr Glu 
            20                  25                  30          


Val Asn Ala Leu Lys Glu Ile Gln Ala Leu Gln Thr Val Cys Leu Arg 
        35                  40                  45              


Gly Thr Lys Val His Lys Lys Cys Tyr Leu Ala Ser Glu Gly Leu Lys 
    50                  55                  60                  


His Phe His Glu Ala Asn Glu Asp Cys Ile Ser Lys Gly Gly Ile Leu 
65                  70                  75                  80  


Val Ile Pro Arg Asn Ser Asp Glu Ile Asn Ala Leu Gln Asp Tyr Gly 
                85                  90                  95      


Lys Arg Ser Leu Pro Gly Val Asn Asp Phe Trp Leu Gly Ile Asn Asp 
            100                 105                 110         


Met Val Thr Glu Gly Lys Phe Val Asp Val Asn Gly Ile Ala Ile Ser 
        115                 120                 125             


Phe Leu Asn Trp Asp Arg Ala Gln Pro Asn Gly Gly Lys Arg Glu Asn 
    130                 135                 140                 


Cys Val Leu Phe Ser Gln Ser Ala Gln Gly Lys Trp Ser Asp Glu Ala 
145                 150                 155                 160 


Cys Arg Ser Ser Lys Arg Tyr Ile Cys Glu Phe Thr Ile Pro Gln 
                165                 170                 175 


<210>  283
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  283

Gln Lys Tyr Ser Gln Leu Leu Glu Lys Lys Thr Thr Lys Glu Leu Val 
1               5                   10                  15      


His Thr Thr Leu Glu Cys Val Lys Lys Asn Met Pro Val Glu Glu Thr 
            20                  25                  30          


Ala Trp Ser Cys Cys Pro Lys Asn Trp Lys Ser Phe Ser Ser Asn Cys 
        35                  40                  45              


Tyr Phe Ile Ser Thr Glu Ser Ala Ser Trp Gln Asp Ser Glu Lys Asp 
    50                  55                  60                  


Cys Ala Arg Met Glu Ala His Leu Leu Val Ile Asn Thr Gln Glu Glu 
65                  70                  75                  80  


Gln Asp Phe Ile Phe Gln Asn Leu Gln Glu Glu Ser Ala Tyr Phe Val 
                85                  90                  95      


Gly Leu Ser Asp Pro Glu Gly Gln Arg His Trp Gln Trp Val Asp Gln 
            100                 105                 110         


Thr Pro Tyr Asn Glu Ser Ser Thr Phe Trp His Pro Arg Glu Pro Ser 
        115                 120                 125             


Asp Pro Asn Glu Arg Cys Val Val Leu Asn Phe Arg Lys Ser Pro Lys 
    130                 135                 140                 


Arg Trp Gly Trp Asn Asp Val Asn Cys Leu Gly Pro Gln Arg Ser Val 
145                 150                 155                 160 


Cys Glu Met Met Lys Ile His Leu 
                165             


<210>  284
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  284

Asn Phe Met Tyr Ser Lys Thr Val Lys Arg Leu Ser Lys Leu Arg Glu 
1               5                   10                  15      


Tyr Gln Gln Tyr His Pro Ser Leu Thr Cys Val Met Glu Gly Lys Asp 
            20                  25                  30          


Ile Glu Asp Trp Ser Cys Cys Pro Thr Pro Trp Thr Ser Phe Gln Ser 
        35                  40                  45              


Ser Cys Tyr Phe Ile Ser Thr Gly Met Gln Ser Trp Thr Lys Ser Gln 
    50                  55                  60                  


Lys Asn Cys Ser Val Met Gly Ala Asp Leu Val Val Ile Asn Thr Arg 
65                  70                  75                  80  


Glu Glu Gln Asp Phe Ile Ile Gln Asn Leu Lys Arg Asn Ser Ser Tyr 
                85                  90                  95      


Phe Leu Gly Leu Ser Asp Pro Gly Gly Arg Arg His Trp Gln Trp Val 
            100                 105                 110         


Asp Gln Thr Pro Tyr Asn Glu Asn Val Thr Phe Trp His Ser Gly Glu 
        115                 120                 125             


Pro Asn Asn Leu Asp Glu Arg Cys Ala Ile Ile Asn Phe Arg Ser Ser 
    130                 135                 140                 


Glu Glu Trp Gly Trp Asn Asp Ile His Cys His Val Pro Gln Lys Ser 
145                 150                 155                 160 


Ile Cys Lys Met Lys Lys Ile Tyr Ile 
                165                 


<210>  285
<211>  179
<212>  PRT
<213>  Homo Sapiens

<400>  285

Arg Cys Val Val Thr Phe Arg Ile Phe Gln Thr Cys Asp Glu Lys Lys 
1               5                   10                  15      


Phe Gln Leu Pro Glu Asn Phe Thr Glu Leu Ser Cys Tyr Asn Tyr Gly 
            20                  25                  30          


Ser Gly Ser Val Lys Asn Cys Cys Pro Leu Asn Trp Glu Tyr Phe Gln 
        35                  40                  45              


Ser Ser Cys Tyr Phe Phe Ser Thr Asp Thr Ile Ser Trp Ala Leu Ser 
    50                  55                  60                  


Leu Lys Asn Cys Ser Ala Met Gly Ala His Leu Val Val Ile Asn Ser 
65                  70                  75                  80  


Gln Glu Glu Gln Glu Phe Leu Ser Tyr Lys Lys Pro Lys Met Arg Glu 
                85                  90                  95      


Phe Phe Ile Gly Leu Ser Asp Gln Val Val Glu Gly Gln Trp Gln Trp 
            100                 105                 110         


Val Asp Gly Thr Pro Leu Thr Lys Ser Leu Ser Phe Trp Asp Val Gly 
        115                 120                 125             


Glu Pro Asn Asn Ile Ala Thr Leu Glu Asp Cys Ala Thr Met Arg Asp 
    130                 135                 140                 


Ser Ser Asn Pro Arg Gln Asn Trp Asn Asp Val Thr Cys Phe Leu Asn 
145                 150                 155                 160 


Tyr Phe Arg Ile Cys Glu Met Val Gly Ile Asn Pro Leu Asn Lys Gly 
                165                 170                 175     


Lys Ser Leu 
            


<210>  286
<211>  507
<212>  PRT
<213>  Homo Sapiens

<400>  286

Gln Gln Gln Thr Arg Pro Val Pro Lys Pro Val Gln Ala Val Ile Leu 
1               5                   10                  15      


Gly Asp Asn Ile Thr Gly His Leu Pro Phe Glu Pro Asn Asn His His 
            20                  25                  30          


His Phe Gly Arg Glu Ala Glu Met Arg Glu Leu Ile Gln Thr Phe Lys 
        35                  40                  45              


Gly His Met Glu Asn Ser Ser Ala Trp Val Val Glu Ile Gln Met Leu 
    50                  55                  60                  


Lys Cys Arg Val Asp Asn Val Asn Ser Gln Leu Gln Val Leu Gly Asp 
65                  70                  75                  80  


His Leu Gly Asn Thr Asn Ala Asp Ile Gln Met Val Lys Gly Val Leu 
                85                  90                  95      


Lys Asp Ala Thr Thr Leu Ser Leu Gln Thr Gln Met Leu Arg Ser Ser 
            100                 105                 110         


Leu Glu Gly Thr Asn Ala Glu Ile Gln Arg Leu Lys Glu Asp Leu Glu 
        115                 120                 125             


Lys Ala Asp Ala Leu Thr Phe Gln Thr Leu Asn Phe Leu Lys Ser Ser 
    130                 135                 140                 


Leu Glu Asn Thr Ser Ile Glu Leu His Val Leu Ser Arg Gly Leu Glu 
145                 150                 155                 160 


Asn Ala Asn Ser Glu Ile Gln Met Leu Asn Ala Ser Leu Glu Thr Ala 
                165                 170                 175     


Asn Thr Gln Ala Gln Leu Ala Asn Ser Ser Leu Lys Asn Ala Asn Ala 
            180                 185                 190         


Glu Ile Tyr Val Leu Arg Gly His Leu Asp Ser Val Asn Asp Leu Arg 
        195                 200                 205             


Thr Gln Asn Gln Val Leu Arg Asn Ser Leu Glu Gly Ala Asn Ala Glu 
    210                 215                 220                 


Ile Gln Gly Leu Lys Glu Asn Leu Gln Asn Thr Asn Ala Leu Asn Ser 
225                 230                 235                 240 


Gln Thr Gln Ala Phe Ile Lys Ser Ser Phe Asp Asn Thr Ser Ala Glu 
                245                 250                 255     


Ile Gln Phe Leu Arg Gly His Leu Glu Arg Ala Gly Asp Glu Ile His 
            260                 265                 270         


Val Leu Lys Arg Asp Leu Lys Met Val Thr Ala Gln Thr Gln Lys Ala 
        275                 280                 285             


Asn Gly Arg Leu Asp Gln Thr Asp Thr Gln Ile Gln Val Phe Lys Ser 
    290                 295                 300                 


Glu Met Glu Asn Val Asn Thr Leu Asn Ala Gln Ile Gln Val Leu Asn 
305                 310                 315                 320 


Gly His Met Lys Asn Ala Ser Arg Glu Ile Gln Thr Leu Lys Gln Gly 
                325                 330                 335     


Met Lys Asn Ala Ser Ala Leu Thr Ser Gln Thr Gln Met Leu Asp Ser 
            340                 345                 350         


Asn Leu Gln Lys Ala Ser Ala Glu Ile Gln Arg Leu Arg Gly Asp Leu 
        355                 360                 365             


Glu Asn Thr Lys Ala Leu Thr Met Glu Ile Gln Gln Glu Gln Ser Arg 
    370                 375                 380                 


Leu Lys Thr Leu His Val Val Ile Thr Ser Gln Glu Gln Leu Gln Arg 
385                 390                 395                 400 


Thr Gln Ser Gln Leu Leu Gln Met Val Leu Gln Gly Trp Lys Phe Asn 
                405                 410                 415     


Gly Gly Ser Leu Tyr Tyr Phe Ser Ser Val Lys Lys Ser Trp His Glu 
            420                 425                 430         


Ala Glu Gln Phe Cys Val Ser Gln Gly Ala His Leu Ala Ser Val Ala 
        435                 440                 445             


Ser Lys Glu Glu Gln Ala Phe Leu Val Glu Phe Thr Ser Lys Val Tyr 
    450                 455                 460                 


Tyr Trp Ile Gly Leu Thr Asp Arg Gly Thr Glu Gly Ser Trp Arg Trp 
465                 470                 475                 480 


Thr Asp Gly Thr Pro Phe Asn Ala Ala Gln Asn Lys Ala Ser His Ser 
                485                 490                 495     


Thr Arg Lys Gly Cys Cys Leu His Leu Thr Val 
            500                 505         


<210>  287
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  287

Leu Ser Lys Ala Ser Thr Glu Arg Ala Ala Leu Leu Asp Gly His Asp 
1               5                   10                  15      


Leu Leu Arg Thr Asn Ala Ser Lys Gln Thr Ala Ala Leu Gly Ala Leu 
            20                  25                  30          


Lys Glu Glu Val Gly Asp Cys His Ser Cys Cys Ser Gly Thr Gln Ala 
        35                  40                  45              


Gln Leu Gln Thr Thr Arg Ala Glu Leu Gly Glu Ala Gln Ala Lys Leu 
    50                  55                  60                  


Met Glu Gln Glu Ser Ala Leu Arg Glu Leu Arg Glu Arg Val Thr Gln 
65                  70                  75                  80  


Gly Leu Ala Glu Ala Gly Arg Gly Arg Glu Asp Val Arg Thr Glu Leu 
                85                  90                  95      


Phe Arg Ala Leu Glu Ala Val Arg Leu Gln Asn Asn Ser Cys Glu Pro 
            100                 105                 110         


Cys Pro Thr Ser Trp Leu Ser Phe Glu Gly Ser Cys Tyr Phe Phe Ser 
        115                 120                 125             


Val Pro Lys Thr Thr Trp Ala Ala Ala Gln Asp His Cys Ala Asp Ala 
    130                 135                 140                 


Ser Ala His Leu Val Ile Val Gly Gly Leu Asp Glu Gln Gly Phe Leu 
145                 150                 155                 160 


Thr Arg Asn Thr Arg Gly Arg Gly Tyr Trp Leu Gly Leu Arg Ala Val 
                165                 170                 175     


Arg His Leu Gly Lys Val Gln Gly Tyr Gln Trp Val Asp Gly Val Ser 
            180                 185                 190         


Leu Ser Phe Ser His Trp Asn Gln Gly Glu Pro Asn Asp Ala Trp Gly 
        195                 200                 205             


Arg Glu Asn Cys Val Met Met Leu His Thr Gly Leu Trp Asn Asp Ala 
    210                 215                 220                 


Pro Cys Asp Ser Glu Lys Asp Gly Trp Ile Cys Glu Lys Arg His Asn 
225                 230                 235                 240 


Cys 
    


<210>  288
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  288

Gln Val Ser Lys Val Pro Ser Ser Leu Ser Gln Glu Gln Ser Glu Gln 
1               5                   10                  15      


Asp Ala Ile Tyr Gln Asn Leu Thr Gln Leu Lys Ala Ala Val Gly Glu 
            20                  25                  30          


Leu Ser Glu Lys Ser Lys Leu Gln Glu Ile Tyr Gln Glu Leu Thr Gln 
        35                  40                  45              


Leu Lys Ala Ala Val Gly Glu Leu Pro Glu Lys Ser Lys Leu Gln Glu 
    50                  55                  60                  


Ile Tyr Gln Glu Leu Thr Arg Leu Lys Ala Ala Val Gly Glu Leu Pro 
65                  70                  75                  80  


Glu Lys Ser Lys Leu Gln Glu Ile Tyr Gln Glu Leu Thr Arg Leu Lys 
                85                  90                  95      


Ala Ala Val Gly Glu Leu Pro Glu Lys Ser Lys Leu Gln Glu Ile Tyr 
            100                 105                 110         


Gln Glu Leu Thr Arg Leu Lys Ala Ala Val Gly Glu Leu Pro Glu Lys 
        115                 120                 125             


Ser Lys Leu Gln Glu Ile Tyr Gln Glu Leu Thr Glu Leu Lys Ala Ala 
    130                 135                 140                 


Val Gly Glu Leu Pro Glu Lys Ser Lys Leu Gln Glu Ile Tyr Gln Glu 
145                 150                 155                 160 


Leu Thr Gln Leu Lys Ala Ala Val Gly Glu Leu Pro Asp Gln Ser Lys 
                165                 170                 175     


Gln Gln Gln Ile Tyr Gln Glu Leu Thr Asp Leu Lys Thr Ala Phe Glu 
            180                 185                 190         


Arg Leu Cys Arg His Cys Pro Lys Asp Trp Thr Phe Phe Gln Gly Asn 
        195                 200                 205             


Cys Tyr Phe Met Ser Asn Ser Gln Arg Asn Trp His Asp Ser Val Thr 
    210                 215                 220                 


Ala Cys Gln Glu Val Arg Ala Gln Leu Val Val Ile Lys Thr Ala Glu 
225                 230                 235                 240 


Glu Gln Asn Phe Leu Gln Leu Gln Thr Ser Arg Ser Asn Arg Phe Ser 
                245                 250                 255     


Trp Met Gly Leu Ser Asp Leu Asn Gln Glu Gly Thr Trp Gln Trp Val 
            260                 265                 270         


Asp Gly Ser Pro Leu Ser Pro Ser Phe Gln Arg Tyr Trp Asn Ser Gly 
        275                 280                 285             


Glu Pro Asn Asn Ser Gly Asn Glu Asp Cys Ala Glu Phe Ser Gly Ser 
    290                 295                 300                 


Gly Trp Asn Asp Asn Arg Cys Asp Val Asp Asn Tyr Trp Ile Cys Lys 
305                 310                 315                 320 


Lys Pro Ala Ala Cys Phe Arg Asp Glu 
                325                 


<210>  289
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  289

Pro Gln Ile Phe Asn Lys Ser Asn Asp Gly Phe Thr Thr Thr Arg Ser 
1               5                   10                  15      


Tyr Gly Thr Val Ser Gln Ile Phe Gly Ser Ser Ser Pro Ser Pro Asn 
            20                  25                  30          


Gly Phe Ile Thr Thr Arg Ser Tyr Gly Thr Val Cys Pro Lys Asp Trp 
        35                  40                  45              


Glu Phe Tyr Gln Ala Arg Cys Phe Phe Leu Ser Thr Ser Glu Ser Ser 
    50                  55                  60                  


Trp Asn Glu Ser Arg Asp Phe Cys Lys Gly Lys Gly Ser Thr Leu Ala 
65                  70                  75                  80  


Ile Val Asn Thr Pro Glu Lys Leu Lys Phe Leu Gln Asp Ile Thr Asp 
                85                  90                  95      


Ala Glu Lys Tyr Phe Ile Gly Leu Ile Tyr His Arg Glu Glu Lys Arg 
            100                 105                 110         


Trp Arg Trp Ile Asn Asn Ser Val Phe Asn Gly Asn Val Thr Asn Gln 
        115                 120                 125             


Asn Gln Asn Phe Asn Cys Ala Thr Ile Gly Leu Thr Lys Thr Phe Asp 
    130                 135                 140                 


Ala Ala Ser Cys Asp Ile Ser Tyr Arg Arg Ile Cys Glu Lys Asn Ala 
145                 150                 155                 160 


Lys 
    


<210>  290
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  290

Thr Tyr His Phe Thr Tyr Gly Glu Thr Gly Lys Arg Leu Ser Glu Leu 
1               5                   10                  15      


His Ser Tyr His Ser Ser Leu Thr Cys Phe Ser Glu Gly Thr Lys Val 
            20                  25                  30          


Pro Ala Trp Gly Cys Cys Pro Ala Ser Trp Lys Ser Phe Gly Ser Ser 
        35                  40                  45              


Cys Tyr Phe Ile Ser Ser Glu Glu Lys Val Trp Ser Lys Ser Glu Gln 
    50                  55                  60                  


Asn Cys Val Glu Met Gly Ala His Leu Val Val Phe Asn Thr Glu Ala 
65                  70                  75                  80  


Glu Gln Asn Phe Ile Val Gln Gln Leu Asn Glu Ser Phe Ser Tyr Phe 
                85                  90                  95      


Leu Gly Leu Ser Asp Pro Gln Gly Asn Asn Asn Trp Gln Trp Ile Asp 
            100                 105                 110         


Lys Thr Pro Tyr Glu Lys Asn Val Arg Phe Trp His Leu Gly Glu Pro 
        115                 120                 125             


Asn His Ser Ala Glu Gln Cys Ala Ser Ile Val Phe Trp Lys Pro Thr 
    130                 135                 140                 


Gly Trp Gly Trp Asn Asp Val Ile Cys Glu Thr Arg Arg Asn Ser Ile 
145                 150                 155                 160 


Cys Glu Met Asn Lys Ile Tyr Leu 
                165             


<210>  291
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  291

Thr Met Gly Val Leu Ser Ser Pro Cys Pro Pro Asn Trp Ile Ile Tyr 
1               5                   10                  15      


Glu Lys Ser Cys Tyr Leu Phe Ser Met Ser Leu Asn Ser Trp Asp Gly 
            20                  25                  30          


Ser Lys Arg Gln Cys Trp Gln Leu Gly Ser Asn Leu Leu Lys Ile Asp 
        35                  40                  45              


Ser Ser Asn Glu Leu Val Ser Val Asp Phe Cys Tyr Asp Tyr Leu Trp 
    50                  55                  60                  


Cys Val Ser 
65          


<210>  292
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  292

Lys Leu Leu Gln Val Ser Thr Ile Ala Met Gln Gln Gln Glu Lys Leu 
1               5                   10                  15      


Ile Gln Gln Glu Arg Ala Leu Leu Asn Phe Thr Glu Trp Lys Arg Ser 
            20                  25                  30          


Cys Ala Leu Gln Met Lys Tyr Cys Gln Ala Phe Met Gln Asn Ser Leu 
        35                  40                  45              


Ser Ser Ala His Asn Ser Ser Pro Cys Pro Asn Asn Trp Ile Gln Asn 
    50                  55                  60                  


Arg Glu Ser Cys Tyr Tyr Val Ser Glu Ile Trp Ser Ile Trp His Thr 
65                  70                  75                  80  


Ser Gln Glu Asn Cys Leu Lys Glu Gly Ser Thr Leu Leu Gln Ile Glu 
                85                  90                  95      


Ser Lys Glu Glu Met Asp Phe Ile Thr Gly Ser Leu Arg Lys Ile Lys 
            100                 105                 110         


Gly Ser Tyr Asp Tyr Trp Val Gly Leu Ser Gln Asp Gly His Ser Gly 
        115                 120                 125             


Arg Trp Leu Trp Gln Asp Gly Ser Ser Pro Ser Pro Gly Leu Leu Pro 
    130                 135                 140                 


Ala Glu Arg Ser Gln Ser Ala Asn Gln Val Cys Gly Tyr Val Lys Ser 
145                 150                 155                 160 


Asn Ser Leu Leu Ser Ser Asn Cys Ser Thr Trp Lys Tyr Phe Ile Cys 
                165                 170                 175     


Glu Lys Tyr Ala Leu Arg Ser Ser Val 
            180                 185 


<210>  293
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  293

Lys Thr Val Arg Thr Ser Pro Leu Glu Leu Ala Phe Pro Leu Gln Arg 
1               5                   10                  15      


Ser Val Ser Phe Asn Phe Ser Thr Val His Lys Ser Cys Pro Ala Lys 
            20                  25                  30          


Asp Trp Lys Val His Lys Gly Lys Cys Tyr Trp Ile Ala Glu Thr Lys 
        35                  40                  45              


Lys Ser Trp Asn Lys Ser Gln Asn Asp Cys Ala Ile Asn Asn Ser Tyr 
    50                  55                  60                  


Leu Met Val Ile Gln Asp Ile Thr Ala Met Val Arg Phe Asn Ile 
65                  70                  75                  


<210>  294
<211>  320
<212>  PRT
<213>  Homo Sapiens

<400>  294

Gln Arg His Ser Pro Gln Glu Ala Pro His Val Gln Tyr Glu Arg Leu 
1               5                   10                  15      


Gly Ser Asp Val Thr Leu Pro Cys Gly Thr Ala Asn Trp Asp Ala Ala 
            20                  25                  30          


Val Thr Trp Arg Val Asn Gly Thr Asp Leu Ala Pro Asp Leu Leu Asn 
        35                  40                  45              


Gly Ser Gln Leu Val Leu His Gly Leu Glu Leu Gly His Ser Gly Leu 
    50                  55                  60                  


Tyr Ala Cys Phe His Arg Asp Ser Trp His Leu Arg His Gln Val Leu 
65                  70                  75                  80  


Leu His Val Gly Leu Pro Pro Arg Glu Pro Val Leu Ser Cys Arg Ser 
                85                  90                  95      


Asn Thr Tyr Pro Lys Gly Phe Tyr Cys Ser Trp His Leu Pro Thr Pro 
            100                 105                 110         


Thr Tyr Ile Pro Asn Thr Phe Asn Val Thr Val Leu His Gly Ser Lys 
        115                 120                 125             


Ile Met Val Cys Glu Lys Asp Pro Ala Leu Lys Asn Arg Cys His Ile 
    130                 135                 140                 


Arg Tyr Met His Leu Phe Ser Thr Ile Lys Tyr Lys Val Ser Ile Ser 
145                 150                 155                 160 


Val Ser Asn Ala Leu Gly His Asn Ala Thr Ala Ile Thr Phe Asp Glu 
                165                 170                 175     


Phe Thr Ile Val Lys Pro Asp Pro Pro Glu Asn Val Val Ala Arg Pro 
            180                 185                 190         


Val Pro Ser Asn Pro Arg Arg Leu Glu Val Thr Trp Gln Thr Pro Ser 
        195                 200                 205             


Thr Trp Pro Asp Pro Glu Ser Phe Pro Leu Lys Phe Phe Leu Arg Tyr 
    210                 215                 220                 


Arg Pro Leu Ile Leu Asp Gln Trp Gln His Val Glu Leu Ser Asp Gly 
225                 230                 235                 240 


Thr Ala His Thr Ile Thr Asp Ala Tyr Ala Gly Lys Glu Tyr Ile Ile 
                245                 250                 255     


Gln Val Ala Ala Lys Asp Asn Glu Ile Gly Thr Trp Ser Asp Trp Ser 
            260                 265                 270         


Val Ala Ala His Ala Thr Pro Trp Thr Glu Glu Pro Arg His Leu Thr 
        275                 280                 285             


Thr Glu Ala Gln Ala Ala Glu Thr Thr Thr Ser Thr Thr Ser Ser Leu 
    290                 295                 300                 


Ala Pro Pro Pro Thr Thr Lys Ile Cys Asp Pro Gly Glu Leu Gly Ser 
305                 310                 315                 320 


<210>  295
<211>  607
<212>  PRT
<213>  Homo Sapiens

<400>  295

Glu Phe Thr Trp Tyr Arg Arg Tyr Gly His Gly Val Ser Glu Glu Asp 
1               5                   10                  15      


Lys Gly Phe Gly Pro Ile Phe Glu Glu Gln Pro Ile Asn Thr Ile Tyr 
            20                  25                  30          


Pro Glu Glu Ser Leu Glu Gly Lys Val Ser Leu Asn Cys Arg Ala Arg 
        35                  40                  45              


Ala Ser Pro Phe Pro Val Tyr Lys Trp Arg Met Asn Asn Gly Asp Val 
    50                  55                  60                  


Asp Leu Thr Ser Asp Arg Tyr Ser Met Val Gly Gly Asn Leu Val Ile 
65                  70                  75                  80  


Asn Asn Pro Asp Lys Gln Lys Asp Ala Gly Ile Tyr Tyr Cys Leu Ala 
                85                  90                  95      


Ser Asn Asn Tyr Gly Met Val Arg Ser Thr Glu Ala Thr Leu Ser Phe 
            100                 105                 110         


Gly Tyr Leu Asp Pro Phe Pro Pro Glu Glu Arg Pro Glu Val Arg Val 
        115                 120                 125             


Lys Glu Gly Lys Gly Met Val Leu Leu Cys Asp Pro Pro Tyr His Phe 
    130                 135                 140                 


Pro Asp Asp Leu Ser Tyr Arg Trp Leu Leu Asn Glu Phe Pro Val Phe 
145                 150                 155                 160 


Ile Thr Met Asp Lys Arg Arg Phe Val Ser Gln Thr Asn Gly Asn Leu 
                165                 170                 175     


Tyr Ile Ala Asn Val Glu Ala Ser Asp Lys Gly Asn Tyr Ser Cys Phe 
            180                 185                 190         


Val Ser Ser Pro Ser Ile Thr Lys Ser Val Phe Ser Lys Phe Ile Pro 
        195                 200                 205             


Leu Ile Pro Ile Pro Glu Arg Thr Thr Lys Pro Tyr Pro Ala Asp Ile 
    210                 215                 220                 


Val Val Gln Phe Lys Asp Val Tyr Ala Leu Met Gly Gln Asn Val Thr 
225                 230                 235                 240 


Leu Glu Cys Phe Ala Leu Gly Asn Pro Val Pro Asp Ile Arg Trp Arg 
                245                 250                 255     


Lys Val Leu Glu Pro Met Pro Ser Thr Ala Glu Ile Ser Thr Ser Gly 
            260                 265                 270         


Ala Val Leu Lys Ile Phe Asn Ile Gln Leu Glu Asp Glu Gly Ile Tyr 
        275                 280                 285             


Glu Cys Glu Ala Glu Asn Ile Arg Gly Lys Asp Lys His Gln Ala Arg 
    290                 295                 300                 


Ile Tyr Val Gln Ala Phe Pro Glu Trp Val Glu His Ile Asn Asp Thr 
305                 310                 315                 320 


Glu Val Asp Ile Gly Ser Asp Leu Tyr Trp Pro Cys Val Ala Thr Gly 
                325                 330                 335     


Lys Pro Ile Pro Thr Ile Arg Trp Leu Lys Asn Gly Tyr Ala Tyr His 
            340                 345                 350         


Lys Gly Glu Leu Arg Leu Tyr Asp Val Thr Phe Glu Asn Ala Gly Met 
        355                 360                 365             


Tyr Gln Cys Ile Ala Glu Asn Thr Tyr Gly Ala Ile Tyr Ala Asn Ala 
    370                 375                 380                 


Glu Leu Lys Ile Leu Ala Leu Ala Pro Thr Phe Glu Met Asn Pro Met 
385                 390                 395                 400 


Lys Lys Lys Ile Leu Ala Ala Lys Gly Gly Arg Val Ile Ile Glu Cys 
                405                 410                 415     


Lys Pro Lys Ala Ala Pro Lys Pro Lys Phe Ser Trp Ser Lys Gly Thr 
            420                 425                 430         


Glu Trp Leu Val Asn Ser Ser Arg Ile Leu Ile Trp Glu Asp Gly Ser 
        435                 440                 445             


Leu Glu Ile Asn Asn Ile Thr Arg Asn Asp Gly Gly Ile Tyr Thr Cys 
    450                 455                 460                 


Phe Ala Glu Asn Asn Arg Gly Lys Ala Asn Ser Thr Gly Thr Leu Val 
465                 470                 475                 480 


Ile Thr Asp Pro Thr Arg Ile Ile Leu Ala Pro Ile Asn Ala Asp Ile 
                485                 490                 495     


Thr Val Gly Glu Asn Ala Thr Met Gln Cys Ala Ala Ser Phe Asp Pro 
            500                 505                 510         


Ala Leu Asp Leu Thr Phe Val Trp Ser Phe Asn Gly Tyr Val Ile Asp 
        515                 520                 525             


Phe Asn Lys Glu Asn Ile His Tyr Gln Arg Asn Phe Met Leu Asp Ser 
    530                 535                 540                 


Asn Gly Glu Leu Leu Ile Arg Asn Ala Gln Leu Lys His Ala Gly Arg 
545                 550                 555                 560 


Tyr Thr Cys Thr Ala Gln Thr Ile Val Asp Asn Ser Ser Ala Ser Ala 
                565                 570                 575     


Asp Leu Val Val Arg Gly Lys Asn Arg Lys Gly Gly Glu Lys Asn Met 
            580                 585                 590         


Val Asp Ser Phe Leu Pro Val Cys Ala Ser Leu Pro Pro Thr Trp 
        595                 600                 605         


<210>  296
<211>  982
<212>  PRT
<213>  Homo Sapiens

<400>  296

Ser Gln Thr Thr Phe Gly Pro Val Phe Glu Asp Gln Pro Leu Ser Val 
1               5                   10                  15      


Leu Phe Pro Glu Glu Ser Thr Glu Glu Gln Val Leu Leu Ala Cys Arg 
            20                  25                  30          


Ala Arg Ala Ser Pro Pro Ala Thr Tyr Arg Trp Lys Met Asn Gly Thr 
        35                  40                  45              


Glu Met Lys Leu Glu Pro Gly Ser Arg His Gln Leu Val Gly Gly Asn 
    50                  55                  60                  


Leu Val Ile Met Asn Pro Thr Lys Ala Gln Asp Ala Gly Val Tyr Gln 
65                  70                  75                  80  


Cys Leu Ala Ser Asn Pro Val Gly Thr Val Val Ser Arg Glu Ala Ile 
                85                  90                  95      


Leu Arg Phe Gly Phe Leu Gln Glu Phe Ser Lys Glu Glu Arg Asp Pro 
            100                 105                 110         


Val Lys Ala His Glu Gly Trp Gly Val Met Leu Pro Cys Asn Pro Pro 
        115                 120                 125             


Ala His Tyr Pro Gly Leu Ser Tyr Arg Trp Leu Leu Asn Glu Phe Pro 
    130                 135                 140                 


Asn Phe Ile Pro Thr Asp Gly Arg His Phe Val Ser Gln Thr Thr Gly 
145                 150                 155                 160 


Asn Leu Tyr Ile Ala Arg Thr Asn Ala Ser Asp Leu Gly Asn Tyr Ser 
                165                 170                 175     


Cys Leu Ala Thr Ser His Met Asp Phe Ser Thr Lys Ser Val Phe Ser 
            180                 185                 190         


Lys Phe Ala Gln Leu Asn Leu Ala Ala Glu Asp Thr Arg Leu Phe Ala 
        195                 200                 205             


Pro Ser Ile Lys Ala Arg Phe Pro Ala Glu Thr Tyr Ala Leu Val Gly 
    210                 215                 220                 


Gln Gln Val Thr Leu Glu Cys Phe Ala Phe Gly Asn Pro Val Pro Arg 
225                 230                 235                 240 


Ile Lys Trp Arg Lys Val Asp Gly Ser Leu Ser Pro Gln Trp Thr Thr 
                245                 250                 255     


Ala Glu Pro Thr Leu Gln Ile Pro Ser Val Ser Phe Glu Asp Glu Gly 
            260                 265                 270         


Thr Tyr Glu Cys Glu Ala Glu Asn Ser Lys Gly Arg Asp Thr Val Gln 
        275                 280                 285             


Gly Arg Ile Ile Val Gln Ala Gln Pro Glu Trp Leu Lys Val Ile Ser 
    290                 295                 300                 


Asp Thr Glu Ala Asp Ile Gly Ser Asn Leu Arg Trp Gly Cys Ala Ala 
305                 310                 315                 320 


Ala Gly Lys Pro Arg Pro Thr Val Arg Trp Leu Arg Asn Gly Glu Pro 
                325                 330                 335     


Leu Ala Ser Gln Asn Arg Val Glu Val Leu Ala Gly Asp Leu Arg Phe 
            340                 345                 350         


Ser Lys Leu Ser Leu Glu Asp Ser Gly Met Tyr Gln Cys Val Ala Glu 
        355                 360                 365             


Asn Lys His Gly Thr Ile Tyr Ala Ser Ala Glu Leu Ala Val Gln Ala 
    370                 375                 380                 


Leu Ala Pro Asp Phe Arg Leu Asn Pro Val Arg Arg Leu Ile Pro Ala 
385                 390                 395                 400 


Ala Arg Gly Gly Glu Ile Leu Ile Pro Cys Gln Pro Arg Ala Ala Pro 
                405                 410                 415     


Lys Ala Val Val Leu Trp Ser Lys Gly Thr Glu Ile Leu Val Asn Ser 
            420                 425                 430         


Ser Arg Val Thr Val Thr Pro Asp Gly Thr Leu Ile Ile Arg Asn Ile 
        435                 440                 445             


Ser Arg Ser Asp Glu Gly Lys Tyr Thr Cys Phe Ala Glu Asn Phe Met 
    450                 455                 460                 


Gly Lys Ala Asn Ser Thr Gly Ile Leu Ser Val Arg Asp Ala Thr Lys 
465                 470                 475                 480 


Ile Thr Leu Ala Pro Ser Ser Ala Asp Ile Asn Leu Gly Asp Asn Leu 
                485                 490                 495     


Thr Leu Gln Cys His Ala Ser His Asp Pro Thr Met Asp Leu Thr Phe 
            500                 505                 510         


Thr Trp Thr Leu Asp Asp Phe Pro Ile Asp Phe Asp Lys Pro Gly Gly 
        515                 520                 525             


His Tyr Arg Arg Thr Asn Val Lys Glu Thr Ile Gly Asp Leu Thr Ile 
    530                 535                 540                 


Leu Asn Ala Gln Leu Arg His Gly Gly Lys Tyr Thr Cys Met Ala Gln 
545                 550                 555                 560 


Thr Val Val Asp Ser Ala Ser Lys Glu Ala Thr Val Leu Val Arg Gly 
                565                 570                 575     


Pro Pro Gly Pro Pro Gly Gly Val Val Val Arg Asp Ile Gly Asp Thr 
            580                 585                 590         


Thr Ile Gln Leu Ser Trp Ser Arg Gly Phe Asp Asn His Ser Pro Ile 
        595                 600                 605             


Ala Lys Tyr Thr Leu Gln Ala Arg Thr Pro Pro Ala Gly Lys Trp Lys 
    610                 615                 620                 


Gln Val Arg Thr Asn Pro Ala Asn Ile Glu Gly Asn Ala Glu Thr Ala 
625                 630                 635                 640 


Gln Val Leu Gly Leu Thr Pro Trp Met Asp Tyr Glu Phe Arg Val Ile 
                645                 650                 655     


Ala Ser Asn Ile Leu Gly Thr Gly Glu Pro Ser Gly Pro Ser Ser Lys 
            660                 665                 670         


Ile Arg Thr Arg Glu Ala Ala Pro Ser Val Ala Pro Ser Gly Leu Ser 
        675                 680                 685             


Gly Gly Gly Gly Ala Pro Gly Glu Leu Ile Val Asn Trp Thr Pro Met 
    690                 695                 700                 


Ser Arg Glu Tyr Gln Asn Gly Asp Gly Phe Gly Tyr Leu Leu Ser Phe 
705                 710                 715                 720 


Arg Arg Gln Gly Ser Thr His Trp Gln Thr Ala Arg Val Pro Gly Ala 
                725                 730                 735     


Asp Ala Gln Tyr Phe Val Tyr Ser Asn Glu Ser Val Arg Pro Tyr Thr 
            740                 745                 750         


Pro Phe Glu Val Lys Ile Arg Ser Tyr Asn Arg Arg Gly Asp Gly Pro 
        755                 760                 765             


Glu Ser Leu Thr Ala Leu Val Tyr Ser Ala Glu Glu Glu Pro Arg Val 
    770                 775                 780                 


Ala Pro Thr Lys Val Trp Ala Lys Gly Val Ser Ser Ser Glu Met Asn 
785                 790                 795                 800 


Val Thr Trp Glu Pro Val Gln Gln Asp Met Asn Gly Ile Leu Leu Gly 
                805                 810                 815     


Tyr Glu Ile Arg Tyr Trp Lys Ala Gly Asp Lys Glu Ala Ala Ala Asp 
            820                 825                 830         


Arg Val Arg Thr Ala Gly Leu Asp Thr Ser Ala Arg Val Ser Gly Leu 
        835                 840                 845             


His Pro Asn Thr Lys Tyr His Val Thr Val Arg Ala Tyr Asn Arg Ala 
    850                 855                 860                 


Gly Thr Gly Pro Ala Ser Pro Ser Ala Asn Ala Thr Thr Met Lys Pro 
865                 870                 875                 880 


Pro Pro Arg Arg Pro Pro Gly Asn Ile Ser Trp Thr Phe Ser Ser Ser 
                885                 890                 895     


Ser Leu Ser Ile Lys Trp Asp Pro Val Val Pro Phe Arg Asn Glu Ser 
            900                 905                 910         


Ala Val Thr Gly Tyr Lys Met Leu Tyr Gln Asn Asp Leu His Leu Thr 
        915                 920                 925             


Pro Thr Leu His Leu Thr Gly Lys Asn Trp Ile Glu Ile Pro Val Pro 
    930                 935                 940                 


Glu Asp Ile Gly His Ala Leu Val Gln Ile Arg Thr Thr Gly Pro Gly 
945                 950                 955                 960 


Gly Asp Gly Ile Pro Ala Glu Val His Ile Val Arg Asn Gly Gly Thr 
                965                 970                 975     


Ser Met Met Val Glu Asn 
            980         


<210>  297
<211>  983
<212>  PRT
<213>  Homo Sapiens

<400>  297

Glu Leu Leu Leu Gln Gly Pro Val Phe Ile Lys Glu Pro Ser Asn Ser 
1               5                   10                  15      


Ile Phe Pro Val Gly Ser Glu Asp Lys Lys Ile Thr Leu His Cys Glu 
            20                  25                  30          


Ala Arg Gly Asn Pro Ser Pro His Tyr Arg Trp Gln Leu Asn Gly Ser 
        35                  40                  45              


Asp Ile Asp Met Ser Met Glu His Arg Tyr Lys Leu Asn Gly Gly Asn 
    50                  55                  60                  


Leu Val Val Ile Asn Pro Asn Arg Asn Trp Asp Thr Gly Thr Tyr Gln 
65                  70                  75                  80  


Cys Phe Ala Thr Asn Ser Leu Gly Thr Ile Val Ser Arg Glu Ala Lys 
                85                  90                  95      


Leu Gln Phe Ala Tyr Leu Glu Asn Phe Lys Thr Lys Met Arg Ser Thr 
            100                 105                 110         


Val Ser Val Arg Glu Gly Gln Gly Val Val Leu Leu Cys Gly Pro Pro 
        115                 120                 125             


Pro His Ser Gly Glu Leu Ser Tyr Ala Trp Ile Phe Asn Glu Tyr Pro 
    130                 135                 140                 


Ser Phe Val Glu Glu Asp Ser Arg Arg Phe Val Ser Gln Glu Thr Gly 
145                 150                 155                 160 


His Leu Tyr Ile Ser Lys Val Glu Pro Ser Asp Val Gly Asn Tyr Thr 
                165                 170                 175     


Cys Val Val Thr Ser Met Val Thr Asn Ala Arg Val Leu Gly Ser Pro 
            180                 185                 190         


Thr Pro Leu Val Leu Arg Ser Asp Gly Val Met Gly Glu Tyr Glu Pro 
        195                 200                 205             


Lys Ile Glu Val Gln Phe Pro Glu Thr Leu Pro Ala Ala Lys Gly Ser 
    210                 215                 220                 


Thr Val Lys Leu Glu Cys Phe Ala Leu Gly Asn Pro Ile Pro Gln Ile 
225                 230                 235                 240 


Asn Trp Arg Arg Ser Asp Gly Leu Pro Phe Ser Ser Lys Ile Lys Leu 
                245                 250                 255     


Arg Lys Phe Ser Gly Val Leu Glu Ile Pro Asn Phe Gln Gln Glu Asp 
            260                 265                 270         


Ala Gly Ser Tyr Glu Cys Ile Ala Glu Asn Ser Arg Gly Lys Asn Val 
        275                 280                 285             


Ala Arg Gly Arg Leu Thr Tyr Tyr Ala Lys Pro His Trp Val Gln Leu 
    290                 295                 300                 


Ile Lys Asp Val Glu Ile Ala Val Glu Asp Ser Leu Tyr Trp Glu Cys 
305                 310                 315                 320 


Arg Ala Ser Gly Lys Pro Lys Pro Ser Tyr Arg Trp Leu Lys Asn Gly 
                325                 330                 335     


Ala Ala Leu Val Leu Glu Glu Arg Thr Gln Ile Glu Asn Gly Ala Leu 
            340                 345                 350         


Thr Ile Ser Asn Leu Ser Val Thr Asp Ser Gly Met Phe Gln Cys Ile 
        355                 360                 365             


Ala Glu Asn Lys His Gly Leu Val Tyr Ser Ser Ala Glu Leu Lys Val 
    370                 375                 380                 


Val Ala Ser Ala Pro Asp Phe Ser Lys Asn Pro Met Lys Lys Leu Val 
385                 390                 395                 400 


Gln Val Gln Val Gly Ser Leu Val Ser Leu Asp Cys Lys Pro Arg Ala 
                405                 410                 415     


Ser Pro Arg Ala Leu Ser Ser Trp Lys Lys Gly Asp Val Ser Val Gln 
            420                 425                 430         


Glu His Glu Arg Ile Ser Leu Leu Asn Asp Gly Gly Leu Lys Ile Ala 
        435                 440                 445             


Asn Val Thr Lys Ala Asp Ala Gly Thr Tyr Thr Cys Met Ala Glu Asn 
    450                 455                 460                 


Gln Phe Gly Lys Ala Asn Gly Thr Thr His Leu Val Val Thr Glu Pro 
465                 470                 475                 480 


Thr Arg Ile Thr Leu Ala Pro Ser Asn Met Asp Val Ser Val Gly Glu 
                485                 490                 495     


Ser Val Ile Leu Pro Cys Gln Val Gln His Asp Pro Leu Leu Asp Ile 
            500                 505                 510         


Ile Phe Thr Trp Tyr Phe Asn Gly Ala Leu Ala Asp Phe Lys Lys Asp 
        515                 520                 525             


Gly Ser His Phe Glu Lys Val Gly Gly Ser Ser Ser Gly Asp Leu Met 
    530                 535                 540                 


Ile Arg Asn Ile Gln Leu Lys His Ser Gly Lys Tyr Val Cys Met Val 
545                 550                 555                 560 


Gln Thr Gly Val Asp Ser Val Ser Ser Ala Ala Asp Leu Ile Val Arg 
                565                 570                 575     


Gly Ser Pro Gly Pro Pro Glu Asn Val Lys Val Asp Glu Ile Thr Asp 
            580                 585                 590         


Thr Thr Ala Gln Leu Ser Trp Lys Glu Gly Lys Asp Asn His Ser Pro 
        595                 600                 605             


Val Ile Ser Tyr Ser Ile Gln Ala Arg Thr Pro Phe Ser Val Gly Trp 
    610                 615                 620                 


Gln Thr Val Thr Thr Val Pro Glu Val Ile Asp Gly Lys Thr His Thr 
625                 630                 635                 640 


Ala Thr Val Val Glu Leu Asn Pro Trp Val Glu Tyr Glu Phe Arg Val 
                645                 650                 655     


Val Ala Ser Asn Lys Ile Gly Gly Gly Glu Pro Ser Leu Pro Ser Glu 
            660                 665                 670         


Lys Val Arg Thr Glu Glu Ala Val Pro Glu Val Pro Pro Ser Glu Val 
        675                 680                 685             


Ser Gly Gly Gly Gly Ser Arg Ser Glu Leu Val Ile Thr Trp Asp Pro 
    690                 695                 700                 


Val Pro Glu Glu Leu Gln Asn Gly Glu Gly Phe Gly Tyr Val Val Ala 
705                 710                 715                 720 


Phe Arg Pro Leu Gly Val Thr Thr Trp Ile Gln Thr Val Val Thr Ser 
                725                 730                 735     


Pro Asp Thr Pro Arg Tyr Val Phe Arg Asn Glu Ser Ile Val Pro Tyr 
            740                 745                 750         


Ser Pro Tyr Glu Val Lys Val Gly Val Tyr Asn Asn Lys Gly Glu Gly 
        755                 760                 765             


Pro Phe Ser Pro Val Thr Thr Val Phe Ser Ala Glu Glu Glu Pro Thr 
    770                 775                 780                 


Val Ala Pro Ser Gln Val Ser Ala Asn Ser Leu Ser Ser Ser Glu Ile 
785                 790                 795                 800 


Glu Val Ser Trp Asn Thr Ile Pro Trp Lys Leu Ser Asn Gly His Leu 
                805                 810                 815     


Leu Gly Tyr Glu Val Arg Tyr Trp Asn Gly Gly Gly Lys Glu Glu Ser 
            820                 825                 830         


Ser Ser Lys Met Lys Val Ala Gly Asn Glu Thr Ser Ala Arg Leu Arg 
        835                 840                 845             


Gly Leu Lys Ser Asn Leu Ala Tyr Tyr Thr Ala Val Arg Ala Tyr Asn 
    850                 855                 860                 


Ser Ala Gly Ala Gly Pro Phe Ser Ala Thr Val Asn Val Thr Thr Lys 
865                 870                 875                 880 


Lys Thr Pro Pro Ser Gln Pro Pro Gly Asn Val Val Trp Asn Ala Thr 
                885                 890                 895     


Asp Thr Lys Val Leu Leu Asn Trp Glu Gln Val Lys Ala Met Glu Asn 
            900                 905                 910         


Glu Ser Glu Val Thr Gly Tyr Lys Val Phe Tyr Arg Thr Ser Ser Gln 
        915                 920                 925             


Asn Asn Val Gln Val Leu Asn Thr Asn Lys Thr Ser Ala Glu Leu Val 
    930                 935                 940                 


Leu Pro Ile Lys Glu Asp Tyr Ile Ile Glu Val Lys Ala Thr Thr Asp 
945                 950                 955                 960 


Gly Gly Asp Gly Thr Ser Ser Glu Gln Ile Arg Ile Pro Arg Ile Thr 
                965                 970                 975     


Ser Met Asp Ala Arg Gly Ser 
            980             


<210>  298
<211>  671
<212>  PRT
<213>  Homo Sapiens

<400>  298

Met Glu Glu Asn Val Phe Trp Glu Cys Lys Ala Asn Gly Arg Pro Lys 
1               5                   10                  15      


Pro Thr Tyr Lys Trp Leu Lys Asn Gly Glu Pro Leu Leu Thr Arg Asp 
            20                  25                  30          


Arg Ile Gln Ile Glu Gln Gly Thr Leu Asn Ile Thr Ile Val Asn Leu 
        35                  40                  45              


Ser Asp Ala Gly Met Tyr Gln Cys Leu Ala Glu Asn Lys His Gly Val 
    50                  55                  60                  


Ile Phe Ser Asn Ala Glu Leu Ser Val Ile Ala Val Gly Pro Asp Phe 
65                  70                  75                  80  


Ser Arg Thr Leu Leu Lys Arg Val Thr Leu Val Lys Val Gly Gly Glu 
                85                  90                  95      


Val Val Ile Glu Cys Lys Pro Lys Ala Ser Pro Lys Pro Val Tyr Thr 
            100                 105                 110         


Trp Lys Lys Gly Arg Asp Ile Leu Lys Glu Asn Glu Arg Ile Thr Ile 
        115                 120                 125             


Ser Glu Asp Gly Asn Leu Arg Ile Ile Asn Val Thr Lys Ser Asp Ala 
    130                 135                 140                 


Gly Ser Tyr Thr Cys Ile Ala Thr Asn His Phe Gly Thr Ala Ser Ser 
145                 150                 155                 160 


Thr Gly Asn Leu Val Val Lys Asp Pro Thr Arg Val Met Val Pro Pro 
                165                 170                 175     


Ser Ser Met Asp Val Thr Val Gly Glu Ser Ile Val Leu Pro Cys Gln 
            180                 185                 190         


Val Thr His Asp His Ser Leu Asp Ile Val Phe Thr Trp Ser Phe Asn 
        195                 200                 205             


Gly His Leu Ile Asp Phe Asp Arg Asp Gly Asp His Phe Glu Arg Val 
    210                 215                 220                 


Gly Gly Asp Ser Ala Gly Asp Leu Met Ile Arg Asn Ile Gln Leu Lys 
225                 230                 235                 240 


His Ala Gly Lys Tyr Val Cys Met Val Gln Thr Ser Val Asp Arg Leu 
                245                 250                 255     


Ser Ala Ala Ala Asp Leu Ile Val Arg Gly Pro Pro Gly Pro Pro Glu 
            260                 265                 270         


Ala Val Thr Ile Asp Glu Ile Thr Asp Thr Thr Ala Gln Leu Ser Trp 
        275                 280                 285             


Arg Pro Gly Pro Asp Asn His Ser Pro Ile Thr Met Tyr Val Ile Gln 
    290                 295                 300                 


Ala Arg Thr Pro Phe Ser Val Gly Trp Gln Ala Val Ser Thr Val Pro 
305                 310                 315                 320 


Glu Leu Ile Asp Gly Lys Thr Phe Thr Ala Thr Val Val Gly Leu Asn 
                325                 330                 335     


Pro Trp Val Glu Tyr Glu Phe Arg Thr Val Ala Ala Asn Val Ile Gly 
            340                 345                 350         


Ile Gly Glu Pro Ser Arg Pro Ser Glu Lys Arg Arg Thr Glu Glu Ala 
        355                 360                 365             


Leu Pro Glu Val Thr Pro Ala Asn Val Ser Gly Gly Gly Gly Ser Lys 
    370                 375                 380                 


Ser Glu Leu Val Ile Thr Trp Glu Thr Val Pro Glu Glu Leu Gln Asn 
385                 390                 395                 400 


Gly Arg Gly Phe Gly Tyr Val Val Ala Phe Arg Pro Tyr Gly Lys Met 
                405                 410                 415     


Ile Trp Met Leu Thr Val Leu Ala Ser Ala Asp Ala Ser Arg Tyr Val 
            420                 425                 430         


Phe Arg Asn Glu Ser Val His Pro Phe Ser Pro Phe Glu Val Lys Val 
        435                 440                 445             


Gly Val Phe Asn Asn Lys Gly Glu Gly Pro Phe Ser Pro Thr Thr Val 
    450                 455                 460                 


Val Tyr Ser Ala Glu Glu Glu Pro Thr Lys Pro Pro Ala Ser Ile Phe 
465                 470                 475                 480 


Ala Arg Ser Leu Ser Ala Thr Asp Ile Glu Val Phe Trp Ala Ser Pro 
                485                 490                 495     


Leu Glu Lys Asn Arg Gly Arg Ile Gln Gly Tyr Glu Val Lys Tyr Trp 
            500                 505                 510         


Arg His Glu Asp Lys Glu Glu Asn Ala Arg Lys Ile Arg Thr Val Gly 
        515                 520                 525             


Asn Gln Thr Ser Thr Lys Ile Thr Asn Leu Lys Gly Ser Val Leu Tyr 
    530                 535                 540                 


His Leu Ala Val Lys Ala Tyr Asn Ser Ala Gly Thr Gly Pro Ser Ser 
545                 550                 555                 560 


Ala Thr Val Asn Val Thr Thr Arg Lys Pro Pro Pro Ser Gln Pro Pro 
                565                 570                 575     


Gly Asn Ile Ile Trp Asn Ser Ser Asp Ser Lys Ile Ile Leu Asn Trp 
            580                 585                 590         


Asp Gln Val Lys Ala Leu Asp Asn Glu Ser Glu Val Lys Gly Tyr Lys 
        595                 600                 605             


Val Leu Tyr Arg Trp Asn Arg Gln Ser Ser Thr Ser Val Ile Glu Thr 
    610                 615                 620                 


Asn Lys Thr Ser Val Glu Leu Ser Leu Pro Phe Asp Glu Asp Tyr Ile 
625                 630                 635                 640 


Ile Glu Ile Lys Pro Phe Ser Asp Gly Gly Asp Gly Ser Ser Ser Glu 
                645                 650                 655     


Gln Ile Arg Ile Pro Lys Ile Ser Asn Ala Tyr Ala Arg Gly Ser 
            660                 665                 670     


<210>  299
<211>  1054
<212>  PRT
<213>  Homo Sapiens

<400>  299

Glu Tyr Ser Lys Ser Leu Pro Gly Leu Ser Thr Ser Tyr Ala Ala Leu 
1               5                   10                  15      


Leu Arg Ile Lys Lys Ser Ser Ser Ser Ser Leu Phe Gly Ser Lys Thr 
            20                  25                  30          


Arg Pro Arg Tyr Ser Ser Pro Ser Leu Gly Thr Leu Ser Ala Ser Ser 
        35                  40                  45              


Pro Ser Trp Leu Gly Ala Ala Gln Asn Tyr Tyr Ser Pro Ile Asn Leu 
    50                  55                  60                  


Tyr His Ser Ser Asp Ala Phe Lys Gln Asp Glu Ser Val Asp Tyr Gly 
65                  70                  75                  80  


Pro Val Phe Val Gln Glu Pro Asp Asp Ile Ile Phe Pro Thr Asp Ser 
                85                  90                  95      


Asp Glu Lys Lys Val Ala Leu Asn Cys Glu Val Arg Gly Asn Pro Val 
            100                 105                 110         


Pro Ser Tyr Arg Trp Leu Arg Asn Gly Thr Glu Ile Asp Leu Glu Ser 
        115                 120                 125             


Asp Tyr Arg Tyr Ser Leu Ile Asp Gly Thr Phe Ile Ile Ser Asn Pro 
    130                 135                 140                 


Ser Glu Ala Lys Asp Ser Gly His Tyr Gln Cys Leu Ala Thr Asn Thr 
145                 150                 155                 160 


Val Gly Ser Ile Leu Ser Arg Glu Ala Thr Leu Gln Phe Ala Tyr Leu 
                165                 170                 175     


Gly Asn Phe Ser Gly Arg Thr Arg Ser Ala Val Ser Val Arg Glu Gly 
            180                 185                 190         


Gln Gly Val Val Leu Met Cys Ser Pro Pro Pro His Ser Pro Glu Ile 
        195                 200                 205             


Ile Tyr Ser Trp Val Phe Asn Glu Phe Pro Ser Phe Val Ala Glu Asp 
    210                 215                 220                 


Ser Arg Arg Phe Ile Ser Gln Glu Thr Gly Asn Leu Tyr Ile Ser Lys 
225                 230                 235                 240 


Val Gln Thr Ser Asp Val Gly Ser Tyr Ile Cys Leu Val Lys Asn Thr 
                245                 250                 255     


Val Thr Asn Ala Arg Val Leu Ser Pro Pro Thr Pro Leu Thr Leu Arg 
            260                 265                 270         


Asn Asp Gly Val Met Gly Glu Tyr Glu Pro Lys Ile Glu Val His Phe 
        275                 280                 285             


Pro Phe Thr Val Thr Ala Ala Lys Gly Thr Thr Val Lys Met Glu Cys 
    290                 295                 300                 


Phe Ala Leu Gly Asn Pro Val Pro Thr Ile Thr Trp Met Lys Val Asn 
305                 310                 315                 320 


Gly Tyr Ile Pro Ser Lys Ala Arg Leu Arg Lys Ser Gln Ala Val Leu 
                325                 330                 335     


Glu Ile Pro Asn Val Gln Leu Asp Asp Ala Gly Ile Tyr Glu Cys Arg 
            340                 345                 350         


Ala Glu Asn Ser Arg Gly Lys Asn Ser Phe Arg Gly Gln Leu Gln Val 
        355                 360                 365             


Tyr Thr Tyr Pro His Trp Val Glu Lys Leu Asn Asp Thr Gln Leu Asp 
    370                 375                 380                 


Ser Gly Ser Pro Leu Arg Trp Glu Cys Lys Ala Thr Gly Lys Pro Arg 
385                 390                 395                 400 


Pro Thr Tyr Arg Trp Leu Lys Asn Gly Val Pro Leu Ser Pro Gln Ser 
                405                 410                 415     


Arg Val Glu Met Val Asn Gly Val Leu Met Ile His Asn Val Asn Gln 
            420                 425                 430         


Ser Asp Ala Gly Met Tyr Gln Cys Leu Ala Glu Asn Lys Tyr Gly Ala 
        435                 440                 445             


Ile Tyr Ala Ser Ala Glu Leu Lys Ile Leu Ala Ser Ala Pro Thr Phe 
    450                 455                 460                 


Ala Leu Asn Gln Leu Lys Lys Thr Ile Ile Val Thr Lys Asp Gln Glu 
465                 470                 475                 480 


Val Val Ile Glu Cys Lys Pro Gln Gly Ser Pro Lys Pro Thr Ile Ser 
                485                 490                 495     


Trp Lys Lys Gly Asp Arg Ala Val Arg Glu Asn Lys Arg Ile Ala Val 
            500                 505                 510         


Leu Pro Asp Gly Ser Leu Arg Ile Leu Asn Ala Ser Lys Ser Asp Glu 
        515                 520                 525             


Gly Lys Tyr Val Cys Arg Gly Glu Asn Val Phe Gly Ser Ala Glu Ile 
    530                 535                 540                 


Ile Ala Ser Leu Ser Val Lys Glu Pro Thr Arg Ile Glu Leu Thr Pro 
545                 550                 555                 560 


Lys Arg Thr Glu Leu Thr Val Gly Glu Ser Ile Val Leu Asn Cys Lys 
                565                 570                 575     


Ala Ile His Asp Ala Ser Leu Asp Val Thr Phe Tyr Trp Thr Leu Lys 
            580                 585                 590         


Gly Gln Pro Ile Asp Phe Glu Glu Glu Gly Gly His Phe Glu Ser Ile 
        595                 600                 605             


Arg Ala Gln Ala Ser Ser Ala Asp Leu Met Ile Arg Asn Ile Leu Leu 
    610                 615                 620                 


Met His Ala Gly Arg Tyr Gly Cys Arg Val Gln Thr Thr Ala Asp Ser 
625                 630                 635                 640 


Val Ser Asp Glu Ala Glu Leu Leu Val Arg Gly Pro Pro Gly Pro Pro 
                645                 650                 655     


Gly Ile Val Ile Val Glu Glu Ile Thr Glu Ser Thr Ala Thr Leu Ser 
            660                 665                 670         


Trp Ser Pro Ala Ala Asp Asn His Ser Pro Ile Ser Ser Tyr Asn Leu 
        675                 680                 685             


Gln Ala Arg Ser Pro Phe Ser Leu Gly Trp Gln Thr Val Lys Thr Val 
    690                 695                 700                 


Pro Glu Ile Ile Thr Gly Asp Met Glu Ser Ala Met Ala Val Asp Leu 
705                 710                 715                 720 


Asn Pro Trp Val Glu Tyr Glu Phe Arg Val Val Ala Thr Asn Pro Ile 
                725                 730                 735     


Gly Thr Gly Asp Pro Ser Thr Pro Ser Arg Met Ile Arg Thr Asn Glu 
            740                 745                 750         


Ala Val Pro Lys Thr Ala Pro Thr Asn Val Ser Gly Arg Ser Gly Arg 
        755                 760                 765             


Arg His Glu Leu Val Ile Ala Trp Glu Pro Val Ser Glu Glu Phe Gln 
    770                 775                 780                 


Asn Gly Glu Gly Phe Gly Tyr Ile Val Ala Phe Arg Pro Asn Gly Thr 
785                 790                 795                 800 


Arg Gly Trp Lys Glu Lys Met Val Thr Ser Ser Glu Ala Ser Lys Phe 
                805                 810                 815     


Ile Tyr Arg Asp Glu Ser Val Pro Pro Leu Thr Pro Phe Glu Val Lys 
            820                 825                 830         


Val Gly Val Tyr Asn Asn Lys Gly Asp Gly Pro Phe Ser Gln Ile Val 
        835                 840                 845             


Val Ile Cys Ser Ala Glu Gly Glu Pro Ser Ala Ala Pro Thr Asp Val 
    850                 855                 860                 


Lys Ala Thr Ser Val Ser Val Ser Glu Ile Leu Val Ala Trp Lys His 
865                 870                 875                 880 


Ile Lys Glu Ser Leu Gly Arg Pro Gln Gly Phe Glu Val Gly Tyr Trp 
                885                 890                 895     


Lys Asp Met Glu Gln Glu Asp Thr Ala Glu Thr Val Lys Thr Arg Gly 
            900                 905                 910         


Asn Glu Ser Phe Val Ile Leu Thr Gly Leu Glu Gly Asn Thr Leu Tyr 
        915                 920                 925             


His Phe Thr Val Arg Ala Tyr Asn Gly Ala Gly Tyr Gly Pro Pro Ser 
    930                 935                 940                 


Ser Glu Val Ser Ala Thr Thr Lys Lys Ser Pro Pro Ser Gln Ala Pro 
945                 950                 955                 960 


Ser Asn Leu Arg Trp Glu Gln Gln Gly Ser Gln Val Ser Leu Gly Trp 
                965                 970                 975     


Glu Pro Val Ile Pro Leu Ala Asn Glu Ser Glu Val Val Gly Tyr Lys 
            980                 985                 990         


Val Phe Tyr Arg Gln Glu Gly His  Ser Asn Ser Gln Val  Ile Glu Thr 
        995                 1000                 1005             


Gln Lys  Leu Gln Ala Val Val  Pro Leu Pro Asp Ala  Gly Val Tyr 
    1010                 1015                 1020             


Ile Ile  Glu Val Arg Ala Tyr  Ser Glu Gly Gly Asp  Gly Thr Ala 
    1025                 1030                 1035             


Ser Ser  Gln Ile Arg Val Pro  Ser Tyr Ser Gly Gly  Lys Ile Thr 
    1040                 1045                 1050             


Ser 
    


<210>  300
<211>  980
<212>  PRT
<213>  Homo Sapiens

<400>  300

Asp Gly Leu Leu Ser Arg Pro Ile Phe Thr Gln Glu Pro His Asp Val 
1               5                   10                  15      


Ile Phe Pro Leu Asp Leu Ser Lys Ser Glu Val Ile Leu Asn Cys Ala 
            20                  25                  30          


Ala Asn Gly Tyr Pro Ser Pro His Tyr Arg Trp Lys Gln Asn Gly Thr 
        35                  40                  45              


Asp Ile Asp Phe Thr Met Ser Tyr His Tyr Arg Leu Asp Gly Gly Ser 
    50                  55                  60                  


Leu Ala Ile Asn Ser Pro His Thr Asp Gln Asp Ile Gly Met Tyr Gln 
65                  70                  75                  80  


Cys Leu Ala Thr Asn Leu Leu Gly Thr Ile Leu Ser Arg Lys Ala Lys 
                85                  90                  95      


Leu Gln Phe Ala Tyr Ile Glu Asp Phe Glu Thr Lys Thr Arg Ser Thr 
            100                 105                 110         


Val Ser Val Arg Glu Gly Gln Gly Val Val Leu Leu Cys Gly Pro Pro 
        115                 120                 125             


Pro His Phe Gly Asp Leu Ser Tyr Ala Trp Thr Phe Asn Asp Asn Pro 
    130                 135                 140                 


Leu Tyr Val Gln Glu Asp Asn Arg Arg Phe Val Ser Gln Glu Thr Gly 
145                 150                 155                 160 


Asn Leu Tyr Ile Ala Lys Val Glu Pro Ser Asp Val Gly Asn Tyr Thr 
                165                 170                 175     


Cys Phe Ile Thr Asn Lys Glu Ala Gln Arg Ser Val Gln Gly Pro Pro 
            180                 185                 190         


Thr Pro Leu Val Gln Arg Thr Asp Gly Val Met Gly Glu Tyr Glu Pro 
        195                 200                 205             


Lys Ile Glu Val Arg Phe Pro Glu Thr Ile Gln Ala Ala Lys Asp Ser 
    210                 215                 220                 


Ser Val Lys Leu Glu Cys Phe Ala Leu Gly Asn Pro Val Pro Asp Ile 
225                 230                 235                 240 


Ser Trp Arg Arg Leu Asp Gly Ser Pro Leu Pro Gly Lys Val Lys Tyr 
                245                 250                 255     


Ser Lys Ser Gln Ala Ile Leu Glu Ile Pro Asn Phe Gln Gln Glu Asp 
            260                 265                 270         


Glu Gly Phe Tyr Glu Cys Ile Ala Ser Asn Leu Arg Gly Arg Asn Leu 
        275                 280                 285             


Ala Lys Gly Gln Leu Ile Phe Tyr Ala Pro Pro Glu Trp Glu Gln Lys 
    290                 295                 300                 


Ile Gln Asn Thr His Leu Ser Ile Tyr Asp Asn Leu Leu Trp Glu Cys 
305                 310                 315                 320 


Lys Ala Ser Gly Lys Pro Asn Pro Trp Tyr Thr Trp Leu Lys Asn Gly 
                325                 330                 335     


Glu Arg Leu Asn Pro Glu Glu Arg Ile Gln Ile Glu Asn Gly Thr Leu 
            340                 345                 350         


Ile Ile Thr Met Leu Asn Val Ser Asp Ser Gly Val Tyr Gln Cys Ala 
        355                 360                 365             


Ala Glu Asn Lys Tyr Gln Ile Ile Tyr Ala Asn Ala Glu Leu Arg Val 
    370                 375                 380                 


Leu Ala Ser Ala Pro Asp Phe Ser Lys Ser Pro Val Lys Lys Lys Ser 
385                 390                 395                 400 


Phe Val Gln Val Gly Gly Asp Ile Val Ile Gly Cys Lys Pro Asn Ala 
                405                 410                 415     


Phe Pro Arg Ala Ala Ile Ser Trp Lys Arg Gly Thr Glu Thr Leu Arg 
            420                 425                 430         


Gln Ser Lys Arg Ile Phe Leu Leu Glu Asp Gly Ser Leu Lys Ile Tyr 
        435                 440                 445             


Asn Ile Thr Arg Ser Asp Ala Gly Ser Tyr Thr Cys Ile Ala Thr Asn 
    450                 455                 460                 


Gln Phe Gly Thr Ala Lys Asn Thr Gly Ser Leu Ile Val Lys Glu Arg 
465                 470                 475                 480 


Thr Val Ile Thr Val Pro Pro Ser Lys Met Asp Val Thr Val Gly Glu 
                485                 490                 495     


Ser Ile Val Leu Pro Cys Gln Val Ser His Asp Pro Ser Ile Glu Val 
            500                 505                 510         


Val Phe Val Trp Phe Phe Asn Gly Asp Val Ile Asp Leu Lys Lys Gly 
        515                 520                 525             


Val Ala His Phe Glu Arg Ile Gly Gly Glu Ser Val Gly Asp Leu Met 
    530                 535                 540                 


Ile Arg Asn Ile Gln Leu His His Ser Gly Lys Tyr Leu Cys Thr Val 
545                 550                 555                 560 


Gln Thr Thr Leu Glu Ser Leu Ser Ala Val Ala Asp Ile Ile Val Arg 
                565                 570                 575     


Gly Pro Pro Gly Pro Pro Glu Asp Val Gln Val Glu Asp Ile Ser Ser 
            580                 585                 590         


Thr Thr Ser Gln Leu Ser Trp Arg Ala Gly Pro Asp Asn Asn Ser Pro 
        595                 600                 605             


Ile Gln Ile Phe Thr Ile Gln Thr Arg Thr Pro Phe Ser Val Gly Trp 
    610                 615                 620                 


Gln Ala Val Ala Thr Val Pro Glu Ile Leu Asn Gly Lys Thr Tyr Asn 
625                 630                 635                 640 


Ala Thr Val Val Gly Leu Ser Pro Trp Val Glu Tyr Glu Phe Arg Val 
                645                 650                 655     


Val Ala Gly Asn Ser Ile Gly Ile Gly Glu Pro Ser Glu Pro Ser Glu 
            660                 665                 670         


Leu Leu Arg Thr Lys Ala Ser Val Pro Val Val Ala Pro Val Asn Ile 
        675                 680                 685             


His Gly Gly Gly Gly Ser Arg Ser Glu Leu Val Ile Thr Trp Glu Ser 
    690                 695                 700                 


Ile Pro Glu Glu Leu Gln Asn Gly Glu Gly Phe Gly Tyr Ile Ile Met 
705                 710                 715                 720 


Phe Arg Pro Val Gly Ser Thr Thr Trp Ser Lys Glu Lys Val Ser Ser 
                725                 730                 735     


Val Glu Ser Ser Arg Phe Val Tyr Arg Asn Glu Ser Ile Ile Pro Leu 
            740                 745                 750         


Ser Pro Phe Glu Val Lys Val Gly Val Tyr Asn Asn Glu Gly Glu Gly 
        755                 760                 765             


Ser Leu Ser Thr Val Thr Ile Val Tyr Ser Gly Glu Asp Glu Pro Gln 
    770                 775                 780                 


Leu Ala Pro Arg Gly Thr Ser Leu Gln Ser Phe Ser Ala Ser Glu Met 
785                 790                 795                 800 


Glu Val Ser Trp Asn Ala Ile Ala Trp Asn Arg Asn Thr Gly Arg Val 
                805                 810                 815     


Leu Gly Tyr Glu Val Leu Tyr Trp Thr Asp Asp Ser Lys Glu Ser Met 
            820                 825                 830         


Ile Gly Lys Ile Arg Val Ser Gly Asn Val Thr Thr Lys Asn Ile Thr 
        835                 840                 845             


Gly Leu Lys Ala Asn Thr Ile Tyr Phe Ala Ser Val Arg Ala Tyr Asn 
    850                 855                 860                 


Thr Ala Gly Thr Gly Pro Ser Ser Pro Pro Val Asn Val Thr Thr Lys 
865                 870                 875                 880 


Lys Ser Pro Pro Ser Gln Pro Pro Ala Asn Ile Ala Trp Lys Leu Thr 
                885                 890                 895     


Asn Ser Lys Leu Cys Leu Asn Trp Glu His Val Lys Thr Met Glu Asn 
            900                 905                 910         


Glu Ser Glu Val Leu Gly Tyr Lys Ile Leu Tyr Arg Gln Asn Arg Gln 
        915                 920                 925             


Ser Lys Thr His Ile Leu Glu Thr Asn Asn Thr Ser Ala Glu Leu Leu 
    930                 935                 940                 


Val Pro Phe Glu Glu Asp Tyr Leu Ile Glu Ile Arg Thr Val Ser Asp 
945                 950                 955                 960 


Gly Gly Asp Gly Ser Ser Ser Glu Glu Ile Arg Ile Pro Lys Met Ser 
                965                 970                 975     


Ser Leu Ser Ser 
            980 


<210>  301
<211>  558
<212>  PRT
<213>  Homo Sapiens

<400>  301

Trp Gly Tyr Tyr Gly Cys Asp Glu Glu Leu Val Gly Pro Leu Tyr Ala 
1               5                   10                  15      


Arg Ser Leu Gly Ala Ser Ser Tyr Tyr Ser Leu Leu Thr Ala Pro Arg 
            20                  25                  30          


Phe Ala Arg Leu His Gly Ile Ser Gly Trp Ser Pro Arg Ile Gly Asp 
        35                  40                  45              


Pro Asn Pro Trp Leu Gln Ile Asp Leu Met Lys Lys His Arg Ile Arg 
    50                  55                  60                  


Ala Val Ala Thr Gln Gly Ser Phe Asn Ser Trp Asp Trp Val Thr Arg 
65                  70                  75                  80  


Tyr Met Leu Leu Tyr Gly Asp Arg Val Asp Ser Trp Thr Pro Phe Tyr 
                85                  90                  95      


Gln Arg Gly His Asn Ser Thr Phe Phe Gly Asn Val Asn Glu Ser Ala 
            100                 105                 110         


Val Val Arg His Asp Leu His Phe His Phe Thr Ala Arg Tyr Ile Arg 
        115                 120                 125             


Ile Val Pro Leu Ala Trp Asn Pro Arg Gly Lys Ile Gly Leu Arg Leu 
    130                 135                 140                 


Gly Leu Tyr Gly Cys Pro Tyr Lys Ala Asp Ile Leu Tyr Phe Asp Gly 
145                 150                 155                 160 


Asp Asp Ala Ile Ser Tyr Arg Phe Pro Arg Gly Val Ser Arg Ser Leu 
                165                 170                 175     


Trp Asp Val Phe Ala Phe Ser Phe Lys Thr Glu Glu Lys Asp Gly Leu 
            180                 185                 190         


Leu Leu His Ala Glu Gly Ala Gln Gly Asp Tyr Val Thr Leu Glu Leu 
        195                 200                 205             


Glu Gly Ala His Leu Leu Leu His Met Ser Leu Gly Ser Ser Pro Ile 
    210                 215                 220                 


Gln Pro Arg Pro Gly His Thr Thr Val Ser Ala Gly Gly Val Leu Asn 
225                 230                 235                 240 


Asp Gln His Trp His Tyr Val Arg Val Asp Arg Phe Gly Arg Asp Val 
                245                 250                 255     


Asn Phe Thr Leu Asp Gly Tyr Val Gln Arg Phe Ile Leu Asn Gly Asp 
            260                 265                 270         


Phe Glu Arg Leu Asn Leu Asp Thr Glu Met Phe Ile Gly Gly Leu Val 
        275                 280                 285             


Gly Ala Ala Arg Lys Asn Leu Ala Tyr Arg His Asn Phe Arg Gly Cys 
    290                 295                 300                 


Ile Glu Asn Val Ile Phe Asn Arg Val Asn Ile Ala Asp Leu Ala Val 
305                 310                 315                 320 


Arg Arg His Ser Arg Ile Thr Phe Glu Gly Lys Val Ala Phe Arg Cys 
                325                 330                 335     


Leu Asp Pro Val Pro His Pro Ile Asn Phe Gly Gly Pro His Asn Phe 
            340                 345                 350         


Val Gln Val Pro Gly Phe Pro Arg Arg Gly Arg Leu Ala Val Ser Phe 
        355                 360                 365             


Arg Phe Arg Thr Trp Asp Leu Thr Gly Leu Leu Leu Phe Ser Arg Leu 
    370                 375                 380                 


Gly Asp Gly Leu Gly His Val Glu Leu Thr Leu Ser Glu Gly Gln Val 
385                 390                 395                 400 


Asn Val Ser Ile Ala Gln Ser Gly Arg Lys Lys Leu Gln Phe Ala Ala 
                405                 410                 415     


Gly Tyr Arg Leu Asn Asp Gly Phe Trp His Glu Val Asn Phe Val Ala 
            420                 425                 430         


Gln Glu Asn His Ala Val Ile Ser Ile Asp Asp Val Glu Gly Ala Glu 
        435                 440                 445             


Val Arg Val Ser Tyr Pro Leu Leu Ile Arg Thr Gly Thr Ser Tyr Phe 
    450                 455                 460                 


Phe Gly Gly Cys Pro Lys Pro Ala Ser Arg Trp Asp Cys His Ser Asn 
465                 470                 475                 480 


Gln Thr Ala Phe His Gly Cys Met Glu Leu Leu Lys Val Asp Gly Gln 
                485                 490                 495     


Leu Val Asn Leu Thr Leu Val Glu Gly Arg Arg Leu Gly Phe Tyr Ala 
            500                 505                 510         


Glu Val Leu Phe Asp Thr Cys Gly Ile Thr Asp Arg Cys Ser Pro Asn 
        515                 520                 525             


Met Cys Glu His Asp Gly Arg Cys Tyr Gln Ser Trp Asp Asp Phe Ile 
    530                 535                 540                 


Cys Tyr Cys Glu Leu Thr Gly Tyr Lys Gly Glu Thr Cys His 
545                 550                 555             


<210>  302
<211>  1235
<212>  PRT
<213>  Homo Sapiens

<400>  302

Ala Pro Ser Thr Ser Gln Lys Cys Asp Glu Pro Leu Val Ser Gly Leu 
1               5                   10                  15      


Pro His Val Ala Phe Ser Ser Ser Ser Ser Ile Ser Gly Ser Tyr Ser 
            20                  25                  30          


Pro Gly Tyr Ala Lys Ile Asn Lys Arg Gly Gly Ala Gly Gly Trp Ser 
        35                  40                  45              


Pro Ser Asp Ser Asp His Tyr Gln Trp Leu Gln Val Asp Phe Gly Asn 
    50                  55                  60                  


Arg Lys Gln Ile Ser Ala Ile Ala Thr Gln Gly Arg Tyr Ser Ser Ser 
65                  70                  75                  80  


Asp Trp Val Thr Gln Tyr Arg Met Leu Tyr Ser Asp Thr Gly Arg Asn 
                85                  90                  95      


Trp Lys Pro Tyr His Gln Asp Gly Asn Ile Trp Ala Phe Pro Gly Asn 
            100                 105                 110         


Ile Asn Ser Asp Gly Val Val Arg His Glu Leu Gln His Pro Ile Ile 
        115                 120                 125             


Ala Arg Tyr Val Arg Ile Val Pro Leu Asp Trp Asn Gly Glu Gly Arg 
    130                 135                 140                 


Ile Gly Leu Arg Ile Glu Val Tyr Gly Cys Ser Tyr Trp Ala Asp Val 
145                 150                 155                 160 


Ile Asn Phe Asp Gly His Val Val Leu Pro Tyr Arg Phe Arg Asn Lys 
                165                 170                 175     


Lys Met Lys Thr Leu Lys Asp Val Ile Ala Leu Asn Phe Lys Thr Ser 
            180                 185                 190         


Glu Ser Glu Gly Val Ile Leu His Gly Glu Gly Gln Gln Gly Asp Tyr 
        195                 200                 205             


Ile Thr Leu Glu Leu Lys Lys Ala Lys Leu Val Leu Ser Leu Asn Leu 
    210                 215                 220                 


Gly Ser Asn Gln Leu Gly Pro Ile Tyr Gly His Thr Ser Val Met Thr 
225                 230                 235                 240 


Gly Ser Leu Leu Asp Asp His His Trp His Ser Val Val Ile Glu Arg 
                245                 250                 255     


Gln Gly Arg Ser Ile Asn Leu Thr Leu Asp Arg Ser Met Gln His Phe 
            260                 265                 270         


Arg Thr Asn Gly Glu Phe Asp Tyr Leu Asp Leu Asp Tyr Glu Ile Thr 
        275                 280                 285             


Phe Gly Gly Ile Pro Phe Ser Gly Lys Pro Ser Ser Ser Ser Arg Lys 
    290                 295                 300                 


Asn Phe Lys Gly Cys Met Glu Ser Ile Asn Tyr Asn Gly Val Asn Ile 
305                 310                 315                 320 


Thr Asp Leu Ala Arg Arg Lys Lys Leu Glu Pro Ser Asn Val Gly Asn 
                325                 330                 335     


Leu Ser Phe Ser Cys Val Glu Pro Tyr Thr Val Pro Val Phe Phe Asn 
            340                 345                 350         


Ala Thr Ser Tyr Leu Glu Val Pro Gly Arg Leu Asn Gln Asp Leu Phe 
        355                 360                 365             


Ser Val Ser Phe Gln Phe Arg Thr Trp Asn Pro Asn Gly Leu Leu Val 
    370                 375                 380                 


Phe Ser His Phe Ala Asp Asn Leu Gly Asn Val Glu Ile Asp Leu Thr 
385                 390                 395                 400 


Glu Ser Lys Val Gly Val His Ile Asn Ile Thr Gln Thr Lys Met Ser 
                405                 410                 415     


Gln Ile Asp Ile Ser Ser Gly Ser Gly Leu Asn Asp Gly Gln Trp His 
            420                 425                 430         


Glu Val Arg Phe Leu Ala Lys Glu Asn Phe Ala Ile Leu Thr Ile Asp 
        435                 440                 445             


Gly Asp Glu Ala Ser Ala Val Arg Thr Asn Ser Pro Leu Gln Val Lys 
    450                 455                 460                 


Thr Gly Glu Lys Tyr Phe Phe Gly Gly Phe Leu Asn Gln Met Asn Asn 
465                 470                 475                 480 


Ser Ser His Ser Val Leu Gln Pro Ser Phe Gln Gly Cys Met Gln Leu 
                485                 490                 495     


Ile Gln Val Asp Asp Gln Leu Val Asn Leu Tyr Glu Val Ala Gln Arg 
            500                 505                 510         


Lys Pro Gly Ser Phe Ala Asn Val Ser Ile Asp Met Cys Ala Ile Ile 
        515                 520                 525             


Asp Arg Cys Val Pro Asn His Cys Glu His Gly Gly Lys Cys Ser Gln 
    530                 535                 540                 


Thr Trp Asp Ser Phe Lys Cys Thr Cys Asp Glu Thr Gly Tyr Ser Gly 
545                 550                 555                 560 


Ala Thr Cys His Asn Ser Ile Tyr Glu Pro Ser Cys Glu Ala Tyr Lys 
                565                 570                 575     


His Leu Gly Gln Thr Ser Asn Tyr Tyr Trp Ile Asp Pro Asp Gly Ser 
            580                 585                 590         


Gly Pro Leu Gly Pro Leu Lys Val Tyr Cys Asn Met Thr Glu Asp Lys 
        595                 600                 605             


Val Trp Thr Ile Val Ser His Asp Leu Gln Met Gln Thr Pro Val Val 
    610                 615                 620                 


Gly Tyr Asn Pro Glu Lys Tyr Ser Val Thr Gln Leu Val Tyr Ser Ala 
625                 630                 635                 640 


Ser Met Asp Gln Ile Ser Ala Ile Thr Asp Ser Ala Glu Tyr Cys Glu 
                645                 650                 655     


Gln Tyr Val Ser Tyr Phe Cys Lys Met Ser Arg Leu Leu Asn Thr Pro 
            660                 665                 670         


Asp Gly Ser Pro Tyr Thr Trp Trp Val Gly Lys Ala Asn Glu Lys His 
        675                 680                 685             


Tyr Tyr Trp Gly Gly Ser Gly Pro Gly Ile Gln Lys Cys Ala Cys Gly 
    690                 695                 700                 


Ile Glu Arg Asn Cys Thr Asp Pro Lys Tyr Tyr Cys Asn Cys Asp Ala 
705                 710                 715                 720 


Asp Tyr Lys Gln Trp Arg Lys Asp Ala Gly Phe Leu Ser Tyr Lys Asp 
                725                 730                 735     


His Leu Pro Val Ser Gln Val Val Val Gly Asp Thr Asp Arg Gln Gly 
            740                 745                 750         


Ser Glu Ala Lys Leu Ser Val Gly Pro Leu Arg Cys Gln Gly Asp Arg 
        755                 760                 765             


Asn Tyr Trp Asn Ala Ala Ser Phe Pro Asn Pro Ser Ser Tyr Leu His 
    770                 775                 780                 


Phe Ser Thr Phe Gln Gly Glu Thr Ser Ala Asp Ile Ser Phe Tyr Phe 
785                 790                 795                 800 


Lys Thr Leu Thr Pro Trp Gly Val Phe Leu Glu Asn Met Gly Lys Glu 
                805                 810                 815     


Asp Phe Ile Lys Leu Glu Leu Lys Ser Ala Thr Glu Val Ser Phe Ser 
            820                 825                 830         


Phe Asp Val Gly Asn Gly Pro Val Glu Ile Val Val Arg Ser Pro Thr 
        835                 840                 845             


Pro Leu Asn Asp Asp Gln Trp His Arg Val Thr Ala Glu Arg Asn Val 
    850                 855                 860                 


Lys Gln Ala Ser Leu Gln Val Asp Arg Leu Pro Gln Gln Ile Arg Lys 
865                 870                 875                 880 


Ala Pro Thr Glu Gly His Thr Arg Leu Glu Leu Tyr Ser Gln Leu Phe 
                885                 890                 895     


Val Gly Gly Ala Gly Gly Gln Gln Gly Phe Leu Gly Cys Ile Arg Ser 
            900                 905                 910         


Leu Arg Met Asn Gly Val Thr Leu Asp Leu Glu Glu Arg Ala Lys Val 
        915                 920                 925             


Thr Ser Gly Phe Ile Ser Gly Cys Ser Gly His Cys Thr Ser Tyr Gly 
    930                 935                 940                 


Thr Asn Cys Glu Asn Gly Gly Lys Cys Leu Glu Arg Tyr His Gly Tyr 
945                 950                 955                 960 


Ser Cys Asp Cys Ser Asn Thr Ala Tyr Asp Gly Thr Phe Cys Asn Lys 
                965                 970                 975     


Asp Val Gly Ala Phe Phe Glu Glu Gly Met Trp Leu Arg Tyr Asn Phe 
            980                 985                 990         


Gln Ala Pro Ala Thr Asn Ala Arg  Asp Ser Ser Ser Arg  Val Asp Asn 
        995                 1000                 1005             


Ala Pro  Asp Gln Gln Asn Ser  His Pro Asp Leu Ala  Gln Glu Glu 
    1010                 1015                 1020             


Ile Arg  Phe Ser Phe Ser Thr  Thr Lys Ala Pro Cys  Ile Leu Leu 
    1025                 1030                 1035             


Tyr Ile  Ser Ser Phe Thr Thr  Asp Phe Leu Ala Val  Leu Val Lys 
    1040                 1045                 1050             


Pro Thr  Gly Ser Leu Gln Ile  Arg Tyr Asn Leu Gly  Gly Thr Arg 
    1055                 1060                 1065             


Glu Pro  Tyr Asn Ile Asp Val  Asp His Arg Asn Met  Ala Asn Gly 
    1070                 1075                 1080             


Gln Pro  His Ser Val Asn Ile  Thr Arg His Glu Lys  Thr Ile Phe 
    1085                 1090                 1095             


Leu Lys  Leu Asp His Tyr Pro  Ser Val Ser Tyr His  Leu Pro Ser 
    1100                 1105                 1110             


Ser Ser  Asp Thr Leu Phe Asn  Ser Pro Lys Ser Leu  Phe Leu Gly 
    1115                 1120                 1125             


Lys Val  Ile Glu Thr Gly Lys  Ile Asp Gln Glu Ile  His Lys Tyr 
    1130                 1135                 1140             


Asn Thr  Pro Gly Phe Thr Gly  Cys Leu Ser Arg Val  Gln Phe Asn 
    1145                 1150                 1155             


Gln Ile  Ala Pro Leu Lys Ala  Ala Leu Arg Gln Thr  Asn Ala Ser 
    1160                 1165                 1170             


Ala His  Val His Ile Gln Gly  Glu Leu Val Glu Ser  Asn Cys Gly 
    1175                 1180                 1185             


Ala Ser  Pro Leu Thr Leu Ser  Pro Met Ser Ser Ala  Thr Asp Pro 
    1190                 1195                 1200             


Trp His  Leu Asp His Leu Asp  Ser Ala Ser Ala Asp  Phe Pro Tyr 
    1205                 1210                 1215             


Asn Pro  Gly Gln Gly Gln Ala  Ile Arg Asn Gly Val  Asn Arg Asn 
    1220                 1225                 1230             


Ser Ala  
    1235 


<210>  303
<211>  877
<212>  PRT
<213>  Homo Sapiens

<400>  303

Gly Asn Pro Pro Asp Cys Asp Ala Pro Leu Ala Ser Ala Leu Pro Arg 
1               5                   10                  15      


Ser Ser Phe Ser Ser Ser Ser Glu Leu Ser Ser Ser His Gly Pro Gly 
            20                  25                  30          


Phe Ser Arg Leu Asn Arg Arg Asp Gly Ala Gly Gly Trp Thr Pro Leu 
        35                  40                  45              


Val Ser Asn Lys Tyr Gln Trp Leu Gln Ile Asp Leu Gly Glu Arg Met 
    50                  55                  60                  


Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asp Trp 
65                  70                  75                  80  


Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Gly Gly Arg Asn Trp Lys 
                85                  90                  95      


Gln Tyr Arg Arg Glu Glu Ser Ile Trp Gly Phe Pro Gly Asn Thr Asn 
            100                 105                 110         


Ala Asp Ser Val Val His Tyr Arg Leu Gln Pro Pro Phe Glu Ala Arg 
        115                 120                 125             


Phe Leu Arg Phe Leu Pro Leu Ala Trp Asn Pro Arg Gly Arg Ile Gly 
    130                 135                 140                 


Met Arg Ile Glu Val Tyr Gly Cys Ala Tyr Lys Ser Glu Val Val Tyr 
145                 150                 155                 160 


Phe Asp Gly Gln Ser Ala Leu Leu Tyr Arg Leu Asp Lys Lys Pro Leu 
                165                 170                 175     


Lys Pro Ile Arg Asp Val Ile Ser Leu Lys Phe Lys Ala Met Gln Ser 
            180                 185                 190         


Asn Gly Ile Leu Leu His Arg Glu Gly Gln His Gly Asn His Ile Thr 
        195                 200                 205             


Leu Glu Leu Ile Lys Gly Lys Leu Val Phe Phe Leu Asn Ser Gly Asn 
    210                 215                 220                 


Ala Lys Leu Pro Ser Thr Ile Ala Pro Val Thr Leu Thr Leu Gly Ser 
225                 230                 235                 240 


Leu Leu Asp Asp Gln His Trp His Ser Val Leu Ile Glu Leu Leu Asp 
                245                 250                 255     


Thr Gln Val Asn Phe Thr Val Asp Lys His Thr His His Phe Gln Ala 
            260                 265                 270         


Lys Gly Asp Ser Ser Tyr Leu Asp Leu Asn Phe Glu Ile Ser Phe Gly 
        275                 280                 285             


Gly Ile Pro Thr Pro Gly Arg Ser Arg Ala Phe Arg Arg Lys Ser Phe 
    290                 295                 300                 


His Gly Cys Leu Glu Asn Leu Tyr Tyr Asn Gly Val Asp Val Thr Glu 
305                 310                 315                 320 


Leu Ala Lys Lys His Lys Pro Gln Ile Leu Met Met Gly Asn Val Ser 
                325                 330                 335     


Phe Ser Cys Pro Gln Pro Gln Thr Val Pro Val Thr Phe Leu Ser Ser 
            340                 345                 350         


Arg Ser Tyr Leu Ala Leu Pro Gly Asn Ser Gly Glu Asp Lys Val Ser 
        355                 360                 365             


Val Thr Phe Gln Phe Arg Thr Trp Asn Arg Ala Gly His Leu Leu Phe 
    370                 375                 380                 


Gly Glu Leu Arg Arg Gly Ser Gly Ser Phe Val Leu Phe Leu Lys Asp 
385                 390                 395                 400 


Gly Lys Leu Lys Leu Ser Leu Phe Gln Pro Gly Gln Ser Pro Arg Asn 
                405                 410                 415     


Val Thr Ala Gly Ala Gly Leu Asn Asp Gly Gln Trp His Ser Val Ser 
            420                 425                 430         


Phe Ser Ala Lys Trp Ser His Met Asn Val Val Val Asp Asp Asp Thr 
        435                 440                 445             


Ala Val Gln Pro Leu Val Ala Val Leu Ile Asp Ser Gly Asp Thr Tyr 
    450                 455                 460                 


Tyr Phe Gly Ala Leu Tyr Glu Gln Ser Cys Glu Ala His Lys His Arg 
465                 470                 475                 480 


Gly Asn Pro Ser Gly Leu Tyr Tyr Ile Asp Ala Asp Gly Ser Gly Pro 
                485                 490                 495     


Leu Gly Pro Phe Leu Val Tyr Cys Asn Met Thr Asp Ala Ala Trp Thr 
            500                 505                 510         


Val Val Gln His Gly Gly Pro Asp Ala Val Thr Leu Arg Gly Ala Pro 
        515                 520                 525             


Ser Gly His Pro Arg Ser Ala Val Ser Phe Ala Tyr Ala Ala Gly Ala 
    530                 535                 540                 


Gly Gln Leu Arg Ser Ala Val Asn Leu Ala Glu Arg Cys Glu Gln Arg 
545                 550                 555                 560 


Leu Ala Leu Arg Cys Gly Thr Ala Arg Arg Pro Asp Ser Arg Asp Gly 
                565                 570                 575     


Thr Pro Leu Ser Trp Trp Val Gly Arg Thr Asn Glu Thr His Thr Tyr 
            580                 585                 590         


Trp Gly Val Ser Leu Pro Asp Ala Gln Lys Cys Thr Cys Gly Leu Glu 
        595                 600                 605             


Gly Asn Cys Ile Asp Ser Gln Tyr Tyr Cys Asn Cys Asp Ala Gly Arg 
    610                 615                 620                 


Asn Glu Trp Thr Ser Asp Thr Ile Val Leu Ser Gln Lys Glu His Leu 
625                 630                 635                 640 


Pro Val Thr Gln Ile Val Met Thr Asp Ala Gly Arg Pro His Ser Glu 
                645                 650                 655     


Ala Ala Tyr Thr Leu Gly Pro Leu Leu Cys Arg Gly Asp Gln Ser Phe 
            660                 665                 670         


Trp Asn Ser Ala Ser Phe Asn Thr Glu Thr Ser Tyr Leu His Phe Pro 
        675                 680                 685             


Ala Phe His Gly Glu Leu Thr Ala Asp Val Cys Phe Phe Phe Lys Thr 
    690                 695                 700                 


Thr Val Ser Ser Gly Val Phe Met Glu Asn Leu Gly Ile Thr Asp Phe 
705                 710                 715                 720 


Ile Arg Ile Glu Leu Arg Ala Pro Thr Glu Val Thr Phe Ser Phe Asp 
                725                 730                 735     


Val Gly Asn Gly Pro Cys Glu Val Thr Val Gln Ser Pro Thr Pro Phe 
            740                 745                 750         


Asn Asp Asn Gln Trp His His Val Arg Ala Glu Arg Asn Val Lys Gly 
        755                 760                 765             


Ala Ser Leu Gln Val Asp Gln Leu Pro Gln Lys Met Gln Pro Ala Pro 
    770                 775                 780                 


Ala Asp Gly His Val Arg Leu Gln Leu Asn Ser Gln Leu Phe Ile Gly 
785                 790                 795                 800 


Gly Thr Ala Thr Arg Gln Arg Gly Phe Leu Gly Cys Ile Arg Ser Leu 
                805                 810                 815     


Gln Leu Asn Gly Val Ala Leu Asp Leu Glu Glu Arg Ala Thr Val Thr 
            820                 825                 830         


Pro Gly Val Glu Pro Gly Cys Ala Gly His Cys Ser Thr Tyr Gly His 
        835                 840                 845             


Leu Cys Arg Asn Gly Gly Arg Cys Arg Glu Lys Arg Arg Gly Val Thr 
    850                 855                 860                 


Cys Asp Cys Ala Phe Ser Ala Tyr Asp Gly Pro Phe Cys 
865                 870                 875         


<210>  304
<211>  1216
<212>  PRT
<213>  Homo Sapiens

<400>  304

Gly Asn Ser Tyr Asp Cys Asp Asp Pro Leu Val Ser Ala Leu Pro Gln 
1               5                   10                  15      


Ala Ser Phe Ser Ser Ser Ser Glu Leu Ser Ser Ser His Gly Pro Gly 
            20                  25                  30          


Phe Ala Arg Leu Asn Arg Arg Asp Gly Ala Gly Gly Trp Ser Pro Leu 
        35                  40                  45              


Val Ser Asn Lys Tyr Gln Trp Leu Gln Ile Asp Leu Gly Glu Arg Met 
    50                  55                  60                  


Glu Val Thr Ala Val Ala Thr Gln Gly Gly Tyr Gly Ser Ser Asn Trp 
65                  70                  75                  80  


Val Thr Ser Tyr Leu Leu Met Phe Ser Asp Ser Gly Trp Asn Trp Lys 
                85                  90                  95      


Gln Tyr Arg Gln Glu Asp Ser Ile Trp Gly Phe Ser Gly Asn Ala Asn 
            100                 105                 110         


Ala Asp Ser Val Val Tyr Tyr Arg Leu Gln Pro Ser Ile Lys Ala Arg 
        115                 120                 125             


Phe Leu Arg Phe Ile Pro Leu Glu Trp Asn Pro Lys Gly Arg Ile Gly 
    130                 135                 140                 


Met Arg Ile Glu Val Phe Gly Cys Ala Tyr Arg Ser Glu Val Val Asp 
145                 150                 155                 160 


Leu Asp Gly Lys Ser Ser Leu Leu Tyr Arg Phe Asp Gln Lys Ser Leu 
                165                 170                 175     


Ser Pro Ile Lys Asp Ile Ile Ser Leu Lys Phe Lys Thr Met Gln Ser 
            180                 185                 190         


Asp Gly Ile Leu Leu His Arg Glu Gly Pro Asn Gly Asp His Ile Thr 
        195                 200                 205             


Leu Gln Leu Arg Arg Ala Arg Leu Phe Leu Leu Ile Asn Ser Gly Glu 
    210                 215                 220                 


Ala Lys Leu Pro Ser Thr Ser Thr Leu Val Asn Leu Thr Leu Gly Ser 
225                 230                 235                 240 


Leu Leu Asp Asp Gln His Trp His Ser Val Leu Ile Gln Arg Leu Gly 
                245                 250                 255     


Lys Gln Val Asn Phe Thr Val Asp Glu His Arg His His Phe His Ala 
            260                 265                 270         


Arg Gly Glu Phe Asn Leu Met Asn Leu Asp Tyr Glu Ile Ser Phe Gly 
        275                 280                 285             


Gly Ile Pro Ala Pro Gly Lys Ser Val Ser Phe Pro His Arg Asn Phe 
    290                 295                 300                 


His Gly Cys Leu Glu Asn Leu Tyr Tyr Asn Gly Val Asp Ile Ile Asp 
305                 310                 315                 320 


Leu Ala Lys Gln Gln Lys Pro Gln Ile Ile Ala Met Gly Asn Val Ser 
                325                 330                 335     


Phe Ser Cys Ser Gln Pro Gln Ser Met Pro Val Thr Phe Leu Ser Ser 
            340                 345                 350         


Arg Ser Tyr Leu Ala Leu Pro Asp Phe Ser Gly Glu Glu Glu Val Ser 
        355                 360                 365             


Ala Thr Phe Gln Phe Arg Thr Trp Asn Lys Ala Gly Leu Leu Leu Phe 
    370                 375                 380                 


Ser Glu Leu Gln Leu Ile Ser Gly Gly Ile Leu Leu Phe Leu Ser Asp 
385                 390                 395                 400 


Gly Lys Leu Lys Ser Asn Leu Tyr Gln Pro Gly Lys Leu Pro Ser Asp 
                405                 410                 415     


Ile Thr Ala Gly Val Glu Leu Asn Asp Gly Gln Trp His Ser Val Ser 
            420                 425                 430         


Leu Ser Ala Lys Lys Asn His Leu Ser Val Ala Val Asp Gly Gln Met 
        435                 440                 445             


Ala Ser Ala Ala Pro Leu Leu Gly Pro Glu Gln Ile Tyr Ser Gly Gly 
    450                 455                 460                 


Thr Tyr Tyr Phe Gly Gly Cys Pro Asp Lys Ser Phe Gly Ser Lys Cys 
465                 470                 475                 480 


Lys Ser Pro Leu Gly Gly Phe Gln Gly Cys Met Arg Leu Ile Ser Ile 
                485                 490                 495     


Ser Gly Lys Val Val Asp Leu Ile Ser Val Gln Gln Gly Ser Leu Gly 
            500                 505                 510         


Asn Phe Ser Asp Leu Gln Ile Asp Ser Cys Gly Ile Ser Asp Arg Cys 
        515                 520                 525             


Leu Pro Asn Tyr Cys Glu His Gly Gly Glu Cys Ser Gln Ser Trp Ser 
    530                 535                 540                 


Thr Phe His Cys Asn Cys Thr Asn Thr Gly Tyr Arg Gly Ala Thr Cys 
545                 550                 555                 560 


His Asn Ser Ile Tyr Glu Gln Ser Cys Glu Ala Tyr Lys His Arg Gly 
                565                 570                 575     


Asn Thr Ser Gly Phe Tyr Tyr Ile Asp Ser Asp Gly Ser Gly Pro Leu 
            580                 585                 590         


Glu Pro Phe Leu Leu Tyr Cys Asn Met Thr Glu Thr Ala Trp Thr Ile 
        595                 600                 605             


Ile Gln His Asn Gly Ser Asp Leu Thr Arg Val Arg Asn Thr Asn Pro 
    610                 615                 620                 


Glu Asn Pro Tyr Ala Gly Phe Phe Glu Tyr Val Ala Ser Met Glu Gln 
625                 630                 635                 640 


Leu Gln Ala Thr Ile Asn Arg Ala Glu His Cys Glu Gln Glu Phe Thr 
                645                 650                 655     


Tyr Tyr Cys Lys Lys Ser Arg Leu Val Asn Lys Gln Asp Gly Thr Pro 
            660                 665                 670         


Leu Ser Trp Trp Val Gly Arg Thr Asn Glu Thr Gln Thr Tyr Trp Gly 
        675                 680                 685             


Gly Ser Ser Pro Asp Leu Gln Lys Cys Thr Cys Gly Leu Glu Gly Asn 
    690                 695                 700                 


Cys Ile Asp Ser Gln Tyr Tyr Cys Asn Cys Asp Ala Asp Arg Asn Glu 
705                 710                 715                 720 


Trp Thr Asn Asp Thr Gly Leu Leu Ala Tyr Lys Glu His Leu Pro Val 
                725                 730                 735     


Thr Lys Ile Val Ile Thr Asp Thr Gly Arg Leu His Ser Glu Ala Ala 
            740                 745                 750         


Tyr Lys Leu Gly Pro Leu Leu Cys Gln Gly Asp Arg Ser Phe Trp Asn 
        755                 760                 765             


Ser Ala Ser Phe Asp Thr Glu Ala Ser Tyr Leu His Phe Pro Thr Phe 
    770                 775                 780                 


His Gly Glu Leu Ser Ala Asp Val Ser Phe Phe Phe Lys Thr Thr Ala 
785                 790                 795                 800 


Ser Ser Gly Val Phe Leu Glu Asn Leu Gly Ile Ala Asp Phe Ile Arg 
                805                 810                 815     


Ile Glu Leu Arg Ser Pro Thr Val Val Thr Phe Ser Phe Asp Val Gly 
            820                 825                 830         


Asn Gly Pro Phe Glu Ile Ser Val Gln Ser Pro Thr His Phe Asn Asp 
        835                 840                 845             


Asn Gln Trp His His Val Arg Val Glu Arg Asn Met Lys Glu Ala Ser 
    850                 855                 860                 


Leu Gln Val Asp Gln Leu Thr Pro Lys Thr Gln Pro Ala Pro Ala Asp 
865                 870                 875                 880 


Gly His Val Leu Leu Gln Leu Asn Ser Gln Leu Phe Val Gly Gly Thr 
                885                 890                 895     


Ala Thr Arg Gln Arg Gly Phe Leu Gly Cys Ile Arg Ser Leu Gln Leu 
            900                 905                 910         


Asn Gly Met Thr Leu Asp Leu Glu Glu Arg Ala Gln Val Thr Pro Glu 
        915                 920                 925             


Val Gln Pro Gly Cys Arg Gly His Cys Ser Ser Tyr Gly Lys Leu Cys 
    930                 935                 940                 


Arg Asn Gly Gly Lys Cys Arg Glu Arg Pro Ile Gly Phe Phe Cys Asp 
945                 950                 955                 960 


Cys Thr Phe Ser Ala Tyr Thr Gly Pro Phe Cys Ser Asn Glu Ile Ser 
                965                 970                 975     


Ala Tyr Phe Gly Ser Gly Ser Ser Val Ile Tyr Asn Phe Gln Glu Asn 
            980                 985                 990         


Tyr Leu Leu Ser Lys Asn Ser Ser  Ser His Ala Ala Ser  Phe His Gly 
        995                 1000                 1005             


Asp Met  Lys Leu Ser Arg Glu  Met Ile Lys Phe Ser  Phe Arg Thr 
    1010                 1015                 1020             


Thr Arg  Thr Pro Ser Leu Leu  Leu Phe Val Ser Ser  Phe Tyr Lys 
    1025                 1030                 1035             


Glu Tyr  Leu Ser Val Ile Ile  Ala Lys Asn Gly Ser  Leu Gln Ile 
    1040                 1045                 1050             


Arg Tyr  Lys Leu Asn Lys Tyr  Gln Glu Pro Asp Val  Val Asn Phe 
    1055                 1060                 1065             


Asp Phe  Lys Asn Met Ala Asp  Gly Gln Leu His His  Ile Met Ile 
    1070                 1075                 1080             


Asn Arg  Glu Glu Gly Val Val  Phe Ile Glu Ile Asp  Asp Asn Arg 
    1085                 1090                 1095             


Arg Arg  Gln Val His Leu Ser  Ser Gly Thr Glu Phe  Ser Ala Val 
    1100                 1105                 1110             


Lys Ser  Leu Val Leu Gly Arg  Ile Leu Glu His Ser  Asp Val Asp 
    1115                 1120                 1125             


Gln Asp  Thr Ala Leu Ala Gly  Ala Gln Gly Phe Thr  Gly Cys Leu 
    1130                 1135                 1140             


Ser Ala  Val Gln Leu Ser His  Val Ala Pro Leu Lys  Ala Ala Leu 
    1145                 1150                 1155             


His Pro  Ser His Pro Asp Pro  Val Thr Val Thr Gly  His Val Thr 
    1160                 1165                 1170             


Glu Ser  Ser Cys Met Ala Gln  Pro Gly Thr Asp Ala  Thr Ser Arg 
    1175                 1180                 1185             


Glu Arg  Thr His Ser Phe Ala  Asp His Ser Gly Thr  Ile Asp Asp 
    1190                 1195                 1200             


Arg Glu  Pro Leu Ala Asn Ala  Ile Lys Ser Asp Ser  Ala 
    1205                 1210                 1215     


<210>  305
<211>  1213
<212>  PRT
<213>  Homo Sapiens

<400>  305

Ala Thr Asn Tyr Asn Cys Asp Asp Pro Leu Ala Ser Leu Leu Ser Pro 
1               5                   10                  15      


Met Ala Phe Ser Ser Ser Ser Asp Leu Thr Gly Thr His Ser Pro Ala 
            20                  25                  30          


Gln Leu Asn Trp Arg Val Gly Thr Gly Gly Trp Ser Pro Ala Asp Ser 
        35                  40                  45              


Asn Ala Gln Gln Trp Leu Gln Met Asp Leu Gly Asn Arg Val Glu Ile 
    50                  55                  60                  


Thr Ala Val Ala Thr Gln Gly Arg Tyr Gly Ser Ser Asp Trp Val Thr 
65                  70                  75                  80  


Ser Tyr Ser Leu Met Phe Ser Asp Thr Gly Arg Asn Trp Lys Gln Tyr 
                85                  90                  95      


Lys Gln Glu Asp Ser Ile Trp Thr Phe Ala Gly Asn Met Asn Ala Asp 
            100                 105                 110         


Ser Val Val His His Lys Leu Leu His Ser Val Arg Ala Arg Phe Val 
        115                 120                 125             


Arg Phe Val Pro Leu Glu Trp Asn Pro Ser Gly Lys Ile Gly Met Arg 
    130                 135                 140                 


Val Glu Val Tyr Gly Cys Ser Tyr Lys Ser Asp Val Ala Asp Phe Asp 
145                 150                 155                 160 


Gly Arg Ser Ser Leu Leu Tyr Arg Phe Asn Gln Lys Leu Met Ser Thr 
                165                 170                 175     


Leu Lys Asp Val Ile Ser Leu Lys Phe Lys Ser Met Gln Gly Asp Gly 
            180                 185                 190         


Val Leu Phe His Gly Glu Gly Gln Arg Gly Asp His Ile Thr Leu Glu 
        195                 200                 205             


Leu Gln Lys Gly Arg Leu Ala Leu His Leu Asn Leu Gly Asp Ser Lys 
    210                 215                 220                 


Ala Arg Leu Ser Ser Ser Leu Pro Ser Ala Thr Leu Gly Ser Leu Leu 
225                 230                 235                 240 


Asp Asp Gln His Trp His Ser Val Leu Ile Glu Arg Val Gly Lys Gln 
                245                 250                 255     


Val Asn Phe Thr Val Asp Lys His Thr Gln His Phe Arg Thr Lys Gly 
            260                 265                 270         


Glu Thr Asp Ala Leu Asp Ile Asp Tyr Glu Leu Ser Phe Gly Gly Ile 
        275                 280                 285             


Pro Val Pro Gly Lys Pro Gly Thr Phe Leu Lys Lys Asn Phe His Gly 
    290                 295                 300                 


Cys Ile Glu Asn Leu Tyr Tyr Asn Gly Val Asn Ile Ile Asp Leu Ala 
305                 310                 315                 320 


Lys Arg Arg Lys His Gln Ile Tyr Thr Gly Asn Val Thr Phe Ser Cys 
                325                 330                 335     


Ser Glu Pro Gln Ile Val Pro Ile Thr Phe Val Asn Ser Ser Gly Ser 
            340                 345                 350         


Tyr Leu Leu Leu Pro Gly Thr Pro Gln Ile Asp Gly Leu Ser Val Ser 
        355                 360                 365             


Phe Gln Phe Arg Thr Trp Asn Lys Asp Gly Leu Leu Leu Ser Thr Glu 
    370                 375                 380                 


Leu Ser Glu Gly Ser Gly Thr Leu Leu Leu Ser Leu Glu Gly Gly Ile 
385                 390                 395                 400 


Leu Arg Leu Val Ile Gln Lys Met Thr Glu Arg Val Ala Glu Ile Leu 
                405                 410                 415     


Thr Gly Ser Asn Leu Asn Asp Gly Leu Trp His Ser Val Ser Ile Asn 
            420                 425                 430         


Ala Arg Arg Asn Arg Ile Thr Leu Thr Leu Asp Asp Glu Ala Ala Pro 
        435                 440                 445             


Pro Ala Pro Asp Ser Thr Trp Val Gln Ile Tyr Ser Gly Asn Ser Tyr 
    450                 455                 460                 


Tyr Phe Gly Gly Cys Pro Asp Asn Leu Thr Asp Ser Gln Cys Leu Asn 
465                 470                 475                 480 


Pro Ile Lys Ala Phe Gln Gly Cys Met Arg Leu Ile Phe Ile Asp Asn 
                485                 490                 495     


Gln Pro Lys Asp Leu Ile Ser Val Gln Gln Gly Ser Leu Gly Asn Phe 
            500                 505                 510         


Ser Asp Leu His Ile Asp Leu Cys Ser Ile Lys Asp Arg Cys Leu Pro 
        515                 520                 525             


Asn Tyr Cys Glu His Gly Gly Ser Cys Ser Gln Ser Trp Thr Thr Phe 
    530                 535                 540                 


Tyr Cys Asn Cys Ser Asp Thr Ser Tyr Thr Gly Ala Thr Cys His Asn 
545                 550                 555                 560 


Ser Ile Tyr Glu Gln Ser Cys Glu Val Tyr Arg His Gln Gly Asn Thr 
                565                 570                 575     


Ala Gly Phe Phe Tyr Ile Asp Ser Asp Gly Ser Gly Pro Leu Gly Pro 
            580                 585                 590         


Leu Gln Val Tyr Cys Asn Ile Thr Glu Asp Lys Ile Trp Thr Ser Val 
        595                 600                 605             


Gln His Asn Asn Thr Glu Leu Thr Arg Val Arg Gly Ala Asn Pro Glu 
    610                 615                 620                 


Lys Pro Tyr Ala Met Ala Leu Asp Tyr Gly Gly Ser Met Glu Gln Leu 
625                 630                 635                 640 


Glu Ala Val Ile Asp Gly Ser Glu His Cys Glu Gln Glu Val Ala Tyr 
                645                 650                 655     


His Cys Arg Arg Ser Arg Leu Leu Asn Thr Pro Asp Gly Thr Pro Phe 
            660                 665                 670         


Thr Trp Trp Ile Gly Arg Ser Asn Glu Arg His Pro Tyr Trp Gly Gly 
        675                 680                 685             


Ser Pro Pro Gly Val Gln Gln Cys Glu Cys Gly Leu Asp Glu Ser Cys 
    690                 695                 700                 


Leu Asp Ile Gln His Phe Cys Asn Cys Asp Ala Asp Lys Asp Glu Trp 
705                 710                 715                 720 


Thr Asn Asp Thr Gly Phe Leu Ser Phe Lys Asp His Leu Pro Val Thr 
                725                 730                 735     


Gln Ile Val Ile Thr Asp Thr Asp Arg Ser Asn Ser Glu Ala Ala Trp 
            740                 745                 750         


Arg Ile Gly Pro Leu Arg Cys Tyr Gly Asp Arg Arg Phe Trp Asn Ala 
        755                 760                 765             


Val Ser Phe Tyr Thr Glu Ala Ser Tyr Leu His Phe Pro Thr Phe His 
    770                 775                 780                 


Ala Glu Phe Ser Ala Asp Ile Ser Phe Phe Phe Lys Thr Thr Ala Leu 
785                 790                 795                 800 


Ser Gly Val Phe Leu Glu Asn Leu Gly Ile Lys Asp Phe Ile Arg Leu 
                805                 810                 815     


Glu Ile Ser Ser Pro Ser Glu Ile Thr Phe Ala Ile Asp Val Gly Asn 
            820                 825                 830         


Gly Pro Val Glu Leu Val Val Gln Ser Pro Ser Leu Leu Asn Asp Asn 
        835                 840                 845             


Gln Trp His Tyr Val Arg Ala Glu Arg Asn Leu Lys Glu Thr Ser Leu 
    850                 855                 860                 


Gln Val Asp Asn Leu Pro Arg Ser Thr Arg Glu Thr Ser Glu Glu Gly 
865                 870                 875                 880 


His Phe Arg Leu Gln Leu Asn Ser Gln Leu Phe Val Gly Gly Thr Ser 
                885                 890                 895     


Ser Arg Gln Lys Gly Phe Leu Gly Cys Ile Arg Ser Leu His Leu Asn 
            900                 905                 910         


Gly Gln Lys Met Asp Leu Glu Glu Arg Ala Lys Val Thr Ser Gly Val 
        915                 920                 925             


Arg Pro Gly Cys Pro Gly His Cys Ser Ser Tyr Gly Ser Ile Cys His 
    930                 935                 940                 


Asn Gly Gly Lys Cys Val Glu Lys His Asn Gly Tyr Leu Cys Asp Cys 
945                 950                 955                 960 


Thr Asn Ser Pro Tyr Glu Gly Pro Phe Cys Lys Lys Glu Val Ser Ala 
                965                 970                 975     


Val Phe Glu Ala Gly Thr Ser Val Thr Tyr Met Phe Gln Glu Pro Tyr 
            980                 985                 990         


Pro Val Thr Lys Asn Ile Ser Leu  Ser Ser Ser Ala Ile  Tyr Thr Asp 
        995                 1000                 1005             


Ser Ala  Pro Ser Lys Glu Asn  Ile Ala Leu Ser Phe  Val Thr Thr 
    1010                 1015                 1020             


Gln Ala  Pro Ser Leu Leu Leu  Phe Ile Asn Ser Ser  Ser Gln Asp 
    1025                 1030                 1035             


Phe Val  Val Val Leu Leu Cys  Lys Asn Gly Ser Leu  Gln Val Arg 
    1040                 1045                 1050             


Tyr His  Leu Asn Lys Glu Glu  Thr His Val Phe Thr  Ile Asp Ala 
    1055                 1060                 1065             


Asp Asn  Phe Ala Asn Arg Arg  Met His His Leu Lys  Ile Asn Arg 
    1070                 1075                 1080             


Glu Gly  Arg Glu Leu Thr Ile  Gln Met Asp Gln Gln  Leu Arg Leu 
    1085                 1090                 1095             


Ser Tyr  Asn Phe Ser Pro Glu  Val Glu Phe Arg Val  Ile Arg Ser 
    1100                 1105                 1110             


Leu Thr  Leu Gly Lys Val Thr  Glu Asn Leu Gly Leu  Asp Ser Glu 
    1115                 1120                 1125             


Val Ala  Lys Ala Asn Ala Met  Gly Phe Ala Gly Cys  Met Ser Ser 
    1130                 1135                 1140             


Val Gln  Tyr Asn His Ile Ala  Pro Leu Lys Ala Ala  Leu Arg His 
    1145                 1150                 1155             


Ala Thr  Val Ala Pro Val Thr  Val His Gly Thr Leu  Thr Glu Ser 
    1160                 1165                 1170             


Ser Cys  Gly Phe Met Val Asp  Ser Asp Val Asn Ala  Val Thr Thr 
    1175                 1180                 1185             


Val His  Ser Ser Ser Asp Pro  Phe Gly Lys Thr Asp  Glu Arg Glu 
    1190                 1195                 1200             


Pro Leu  Thr Asn Ala Val Arg  Ser Asp Ser 
    1205                 1210             


<210>  306
<211>  759
<212>  PRT
<213>  Homo Sapiens

<400>  306

Met Asp Pro Gly Ala Leu Glu Met Lys Asn Phe Asn Lys Ile Ile Ser 
1               5                   10                  15      


Phe Leu Tyr Ser Thr Val Gly Ala Leu Asn Lys Ile Gly Thr Asp Gly 
            20                  25                  30          


Thr Gln Val Ala Met Val Gln Phe Thr Asp Asp Pro Arg Thr Glu Phe 
        35                  40                  45              


Lys Leu Asn Ala Tyr Lys Thr Lys Glu Thr Leu Leu Asp Ala Ile Lys 
    50                  55                  60                  


His Ile Ser Tyr Lys Gly Gly Asn Thr Lys Thr Gly Lys Ala Ile Lys 
65                  70                  75                  80  


Tyr Val Arg Asp Thr Leu Phe Thr Ala Glu Ser Gly Thr Arg Arg Gly 
                85                  90                  95      


Ile Pro Lys Val Ile Val Val Ile Thr Asp Gly Arg Ser Gln Asp Asp 
            100                 105                 110         


Val Asn Lys Ile Ser Arg Glu Met Gln Leu Asp Gly Tyr Ser Ile Phe 
        115                 120                 125             


Ala Ile Gly Val Ala Asp Ala Asp Tyr Ser Glu Leu Val Ser Ile Gly 
    130                 135                 140                 


Ser Lys Pro Ser Ala Arg His Val Phe Phe Val Asp Asp Phe Asp Ala 
145                 150                 155                 160 


Phe Lys Lys Ile Glu Asp Glu Leu Ile Thr Phe Val Cys Glu Thr Ala 
                165                 170                 175     


Ser Ala Thr Cys Pro Val Val His Lys Asp Gly Ile Asp Leu Ala Gly 
            180                 185                 190         


Phe Lys Met Met Glu Met Phe Gly Leu Val Glu Lys Asp Phe Ser Ser 
        195                 200                 205             


Val Glu Gly Val Ser Met Glu Pro Gly Thr Phe Asn Val Phe Pro Cys 
    210                 215                 220                 


Tyr Gln Leu His Lys Asp Ala Leu Val Ser Gln Pro Thr Arg Tyr Leu 
225                 230                 235                 240 


His Pro Glu Gly Leu Pro Ser Asp Tyr Thr Ile Ser Phe Leu Phe Arg 
                245                 250                 255     


Ile Leu Pro Asp Thr Pro Gln Glu Pro Phe Ala Leu Trp Glu Ile Leu 
            260                 265                 270         


Asn Lys Asn Ser Asp Pro Leu Val Gly Val Ile Leu Asp Asn Gly Gly 
        275                 280                 285             


Lys Thr Leu Thr Tyr Phe Asn Tyr Asp Gln Ser Gly Asp Phe Gln Thr 
    290                 295                 300                 


Leu Thr Phe Glu Gly Pro Glu Ile Arg Lys Ile Phe Tyr Gly Ser Phe 
305                 310                 315                 320 


His Lys Leu His Ile Val Val Ser Glu Thr Leu Val Lys Val Val Ile 
                325                 330                 335     


Asp Cys Lys Gln Val Gly Glu Lys Ala Met Asn Ala Ser Ala Asn Ile 
            340                 345                 350         


Thr Ser Asp Gly Val Glu Val Leu Gly Lys Met Val Arg Ser Arg Gly 
        355                 360                 365             


Pro Gly Gly Asn Ser Ala Pro Phe Gln Leu Gln Met Phe Asp Ile Val 
    370                 375                 380                 


Cys Ser Thr Ser Trp Ala Asn Thr Asp Lys Cys Cys Glu Leu Pro Gly 
385                 390                 395                 400 


Leu Arg Asp Asp Glu Ser Cys Pro Asp Leu Pro His Ser Cys Ser Cys 
                405                 410                 415     


Ser Glu Thr Asn Glu Val Ala Leu Gly Pro Ala Gly Pro Pro Gly Gly 
            420                 425                 430         


Pro Gly Leu Arg Gly Pro Lys Gly Gln Gln Gly Glu Pro Gly Pro Lys 
        435                 440                 445             


Gly Pro Asp Gly Pro Arg Gly Glu Ile Gly Leu Pro Gly Pro Gln Gly 
    450                 455                 460                 


Pro Pro Gly Pro Gln Gly Pro Ser Gly Leu Ser Ile Gln Gly Met Pro 
465                 470                 475                 480 


Gly Met Pro Gly Glu Lys Gly Glu Lys Gly Asp Thr Gly Leu Pro Gly 
                485                 490                 495     


Pro Gln Gly Ile Pro Gly Gly Val Gly Ser Pro Gly Arg Asp Gly Ser 
            500                 505                 510         


Pro Gly Gln Arg Gly Leu Pro Gly Lys Asp Gly Ser Ser Gly Pro Pro 
        515                 520                 525             


Gly Pro Pro Gly Pro Ile Gly Ile Pro Gly Thr Pro Gly Val Pro Gly 
    530                 535                 540                 


Ile Thr Gly Ser Met Gly Pro Gln Gly Ala Leu Gly Pro Pro Gly Val 
545                 550                 555                 560 


Pro Gly Ala Lys Gly Glu Arg Gly Glu Arg Gly Asp Leu Gln Ser Gln 
                565                 570                 575     


Ala Met Val Arg Ser Val Ala Arg Gln Val Cys Glu Gln Leu Ile Gln 
            580                 585                 590         


Ser His Met Ala Arg Tyr Thr Ala Ile Leu Asn Gln Ile Pro Ser His 
        595                 600                 605             


Ser Ser Ser Ile Arg Thr Val Gln Gly Pro Pro Gly Glu Pro Gly Arg 
    610                 615                 620                 


Pro Gly Ser Pro Gly Ala Pro Gly Glu Gln Gly Pro Pro Gly Thr Pro 
625                 630                 635                 640 


Gly Phe Pro Gly Asn Ala Gly Val Pro Gly Thr Pro Gly Glu Arg Gly 
                645                 650                 655     


Leu Thr Gly Ile Lys Gly Glu Lys Gly Asn Pro Gly Val Gly Thr Gln 
            660                 665                 670         


Gly Pro Arg Gly Pro Pro Gly Pro Ala Gly Pro Ser Gly Glu Ser Arg 
        675                 680                 685             


Pro Gly Ser Pro Gly Pro Pro Gly Ser Pro Gly Pro Arg Gly Pro Pro 
    690                 695                 700                 


Gly His Leu Gly Val Pro Gly Pro Gln Gly Pro Ser Gly Gln Pro Gly 
705                 710                 715                 720 


Tyr Cys Asp Pro Ser Ser Cys Ser Ala Tyr Gly Val Arg Ala Pro His 
                725                 730                 735     


Pro Asp Gln Pro Glu Phe Thr Pro Val Gln Asp Glu Leu Glu Ala Met 
            740                 745                 750         


Glu Leu Trp Gly Pro Gly Val 
        755                 


<210>  307
<211>  1262
<212>  PRT
<213>  Homo Sapiens

<400>  307

Arg Glu Gln Val Gln Ala Ser Gly Leu Leu Arg Leu Ala Val Leu Pro 
1               5                   10                  15      


Glu Asp Arg Leu Gln Met Lys Trp Arg Glu Ser Glu Gly Ser Gly Leu 
            20                  25                  30          


Gly Tyr Leu Val Gln Val Lys Pro Met Ala Gly Asp Ser Glu Gln Glu 
        35                  40                  45              


Val Ile Leu Thr Thr Lys Thr His Lys Ala Thr Val Gly Gly Leu Ser 
    50                  55                  60                  


Pro Ser Lys Gly Tyr Thr Leu Gln Ile Phe Glu Leu Thr Gly Ser Gly 
65                  70                  75                  80  


Arg Phe Leu Leu Ala Arg Arg Glu Phe Val Ile Glu Asp Leu Lys Ser 
                85                  90                  95      


Ser Ser Leu Asp Arg Ser Ser Gln Arg Pro Leu Gly Ser Gly Ala Pro 
            100                 105                 110         


Glu Pro Thr Pro Ser His Thr Gly Ser Pro Asp Pro Glu Gln Ala Ser 
        115                 120                 125             


Glu Pro Gln Val Ala Phe Thr Pro Ser Gln Asp Pro Arg Thr Pro Ala 
    130                 135                 140                 


Gly Pro Gln Phe Arg Cys Leu Pro Pro Val Pro Ala Asp Met Val Phe 
145                 150                 155                 160 


Leu Val Asp Gly Ser Trp Ser Ile Gly His Ser His Phe Gln Gln Val 
                165                 170                 175     


Lys Asp Phe Leu Ala Ser Val Ile Ala Pro Phe Glu Ile Gly Pro Asp 
            180                 185                 190         


Lys Val Gln Val Gly Leu Thr Gln Tyr Ser Gly Asp Ala Gln Thr Glu 
        195                 200                 205             


Trp Asp Leu Asn Ser Leu Ser Thr Lys Glu Gln Val Leu Ala Ala Val 
    210                 215                 220                 


Arg Arg Leu Arg Tyr Lys Gly Gly Asn Thr Phe Thr Gly Leu Ala Leu 
225                 230                 235                 240 


Thr His Val Leu Gly Gln Asn Leu Gln Pro Ala Ala Gly Leu Arg Pro 
                245                 250                 255     


Glu Ala Ala Lys Val Val Ile Leu Val Thr Asp Gly Lys Ser Gln Asp 
            260                 265                 270         


Asp Val His Thr Ala Ala Arg Val Leu Lys Asp Leu Gly Val Asn Val 
        275                 280                 285             


Phe Ala Val Gly Val Lys Asn Ala Asp Glu Ala Glu Leu Arg Leu Leu 
    290                 295                 300                 


Ala Ser Pro Pro Arg Asp Ile Thr Val His Ser Val Leu Asp Phe Leu 
305                 310                 315                 320 


Gln Leu Gly Ala Leu Ala Gly Leu Leu Ser Arg Leu Ile Cys Gln Arg 
                325                 330                 335     


Leu Gln Gly Gly Ser Pro Arg Gln Gly Pro Ala Ala Ala Pro Ala Leu 
            340                 345                 350         


Asp Thr Leu Pro Ala Pro Thr Ser Leu Val Leu Ser Gln Val Thr Ser 
        355                 360                 365             


Ser Ser Ile Arg Leu Ser Trp Thr Pro Ala Pro Arg His Pro Leu Lys 
    370                 375                 380                 


Tyr Leu Ile Val Trp Arg Ala Ser Arg Gly Gly Thr Pro Arg Glu Val 
385                 390                 395                 400 


Val Val Glu Gly Pro Ala Ala Ser Thr Glu Leu His Asn Leu Ala Ser 
                405                 410                 415     


Arg Thr Glu Tyr Leu Val Ser Val Phe Pro Ile Tyr Glu Gly Gly Val 
            420                 425                 430         


Gly Glu Gly Leu Arg Gly Leu Val Thr Thr Ala Pro Leu Pro Pro Pro 
        435                 440                 445             


Arg Ala Leu Thr Leu Ala Ala Val Thr Pro Arg Thr Val His Leu Thr 
    450                 455                 460                 


Trp Gln Pro Ser Ala Gly Ala Thr His Tyr Leu Val Arg Cys Ser Pro 
465                 470                 475                 480 


Ala Ser Pro Lys Gly Glu Glu Glu Glu Arg Glu Val Gln Val Gly Arg 
                485                 490                 495     


Pro Glu Val Leu Leu Asp Gly Leu Glu Pro Gly Arg Asp Tyr Glu Val 
            500                 505                 510         


Ser Val Gln Ser Leu Arg Gly Pro Glu Gly Ser Glu Ala Arg Gly Ile 
        515                 520                 525             


Arg Ala Arg Thr Pro Thr Leu Ala Pro Pro Arg His Leu Gly Phe Ser 
    530                 535                 540                 


Asp Val Ser His Asp Ala Ala Arg Val Phe Trp Glu Gly Ala Pro Arg 
545                 550                 555                 560 


Pro Val Arg Leu Val Arg Val Thr Tyr Val Ser Ser Glu Gly Gly His 
                565                 570                 575     


Ser Gly Gln Thr Glu Ala Pro Gly Asn Ala Thr Ser Ala Thr Leu Gly 
            580                 585                 590         


Pro Leu Ser Ser Ser Thr Thr Tyr Thr Val Arg Val Thr Cys Leu Tyr 
        595                 600                 605             


Pro Gly Gly Gly Ser Ser Thr Leu Thr Gly Arg Val Thr Thr Lys Lys 
    610                 615                 620                 


Ala Pro Ser Pro Ser Gln Leu Ser Met Thr Glu Leu Pro Gly Asp Ala 
625                 630                 635                 640 


Val Gln Leu Ala Trp Val Ala Ala Ala Pro Ser Gly Val Leu Val Tyr 
                645                 650                 655     


Gln Ile Thr Trp Thr Pro Leu Gly Glu Gly Lys Ala His Glu Ile Ser 
            660                 665                 670         


Val Pro Gly Asn Leu Gly Thr Ala Val Leu Pro Gly Leu Gly Arg His 
        675                 680                 685             


Thr Glu Tyr Asp Val Thr Ile Leu Ala Tyr Tyr Arg Asp Gly Ala Arg 
    690                 695                 700                 


Ser Asp Pro Val Ser Leu Arg Tyr Thr Pro Ser Thr Val Ser Arg Ser 
705                 710                 715                 720 


Pro Pro Ser Asn Leu Ala Leu Ala Ser Glu Thr Pro Asp Ser Leu Gln 
                725                 730                 735     


Val Ser Trp Thr Pro Pro Leu Gly Arg Val Leu His Tyr Trp Leu Thr 
            740                 745                 750         


Tyr Ala Pro Ala Ser Gly Leu Gly Pro Glu Lys Ser Val Ser Val Pro 
        755                 760                 765             


Gly Ala Arg Ser His Val Thr Leu Pro Asp Leu Gln Ala Ala Thr Lys 
    770                 775                 780                 


Tyr Arg Val Leu Val Ser Ala Ile Tyr Ala Ala Gly Arg Ser Glu Ala 
785                 790                 795                 800 


Val Ser Ala Thr Gly Gln Thr Ala Cys Pro Ala Leu Arg Pro Asp Gly 
                805                 810                 815     


Ser Leu Pro Gly Phe Asp Leu Met Val Ala Phe Ser Leu Val Glu Lys 
            820                 825                 830         


Ala Tyr Ala Ser Ile Arg Gly Val Ala Met Glu Pro Ser Ala Phe Gly 
        835                 840                 845             


Gly Thr Pro Thr Phe Thr Leu Phe Lys Asp Ala Gln Leu Thr Arg Arg 
    850                 855                 860                 


Val Ser Asp Val Tyr Pro Ala Pro Leu Pro Pro Glu His Thr Ile Val 
865                 870                 875                 880 


Phe Leu Val Arg Leu Leu Pro Glu Thr Pro Arg Glu Ala Phe Ala Leu 
                885                 890                 895     


Trp Gln Met Thr Ala Lys Asp Phe Gln Pro Leu Leu Gly Val Leu Leu 
            900                 905                 910         


Asp Ala Gly Lys Lys Ser Leu Thr Tyr Phe His Arg Asp Pro Arg Ala 
        915                 920                 925             


Ala Leu Gln Glu Ala Thr Phe Asp Pro Gln Glu Val Arg Lys Ile Phe 
    930                 935                 940                 


Phe Gly Ser Phe His Lys Val His Val Ala Val Gly Arg Ser Lys Val 
945                 950                 955                 960 


Arg Leu Tyr Val Asp Cys Arg Lys Val Ala Glu Arg Pro Leu Gly Glu 
                965                 970                 975     


Met Gly Ser Pro Pro Ala Ala Gly Phe Val Thr Leu Gly Arg Leu Ala 
            980                 985                 990         


Lys Ala Arg Gly Pro Arg Ser Ser  Ser Ala Ala Phe Gln  Leu Gln Met 
        995                 1000                 1005             


Leu Gln  Ile Val Cys Ser Asp  Thr Trp Ala Asp Glu  Asp Arg Cys 
    1010                 1015                 1020             


Cys Glu  Leu Pro Ala Ser Arg  Asp Gly Glu Thr Cys  Pro Ala Phe 
    1025                 1030                 1035             


Val Ser  Ala Cys Ser Cys Ser  Ser Glu Thr Pro Gly  Pro Pro Gly 
    1040                 1045                 1050             


Pro Gln  Gly Pro Pro Gly Leu  Pro Gly Arg Asn Gly  Thr Pro Gly 
    1055                 1060                 1065             


Glu Gln  Gly Phe Pro Gly Pro  Arg Gly Pro Pro Gly  Val Lys Gly 
    1070                 1075                 1080             


Glu Lys  Gly Asp His Gly Leu  Pro Gly Leu Gln Gly  His Pro Gly 
    1085                 1090                 1095             


His Gln  Gly Ile Pro Gly Arg  Val Gly Leu Gln Gly  Pro Lys Gly 
    1100                 1105                 1110             


Met Arg  Gly Leu Glu Gly Thr  Ala Gly Leu Pro Gly  Pro Pro Gly 
    1115                 1120                 1125             


Pro Arg  Gly Phe Gln Gly Met  Ala Gly Ala Arg Gly  Thr Ser Gly 
    1130                 1135                 1140             


Glu Arg  Gly Pro Pro Gly Thr  Val Gly Pro Thr Gly  Leu Pro Gly 
    1145                 1150                 1155             


Pro Lys  Gly Glu Arg Gly Glu  Lys Gly Glu Gln Gln  Ser Leu Ala 
    1160                 1165                 1170             


Thr Leu  Tyr Gln Leu Val Ser  Gln Ala Ser His Val  Ser Lys Phe 
    1175                 1180                 1185             


Asp Ser  Phe His Glu Asn Thr  Arg Pro Pro Met Pro  Ile Leu Glu 
    1190                 1195                 1200             


Gln Lys  Leu Glu Pro Gly Thr  Glu Pro Leu Gly Ser  Pro Gly Thr 
    1205                 1210                 1215             


Arg Ser  Lys Ala Leu Val Pro  Gly Glu Trp Gly Arg  Gly Gly Arg 
    1220                 1225                 1230             


His Leu  Glu Gly Arg Gly Glu  Pro Gly Ala Val Gly  Gln Met Gly 
    1235                 1240                 1245             


Ser Pro  Gly Gln Gln Gly Ala  Ser Thr Gln Gly Leu  Trp Glu 
    1250                 1255                 1260         


<210>  308
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  308

Leu Asp Ile Asp Ser Arg Pro Thr Ala Glu Val Cys Ala Thr His Thr 
1               5                   10                  15      


Ile Ser Pro Gly Pro Lys Gly Asp Asp Gly Glu Lys Gly Asp Pro Gly 
            20                  25                  30          


Glu Glu Gly Lys His Gly Lys Val Gly Arg Met Gly Pro Lys Gly Ile 
        35                  40                  45              


Lys Gly Glu Leu Gly Asp Met Gly Asp Gln Gly Asn Ile Gly Lys Thr 
    50                  55                  60                  


Gly Pro Ile Gly Lys Lys Gly Asp Lys Gly Glu Lys Gly Leu Leu Gly 
65                  70                  75                  80  


Ile Pro Gly Glu Lys Gly Lys Ala Gly Thr Val Cys Asp Cys Gly Arg 
                85                  90                  95      


Tyr Arg Lys Phe Val Gly Gln Leu Asp Ile Ser Ile Ala Arg Leu Lys 
            100                 105                 110         


Thr Ser Met Lys Phe Val Lys Asn Val Ile Ala Gly Ile Arg Glu Thr 
        115                 120                 125             


Glu Glu Lys Phe Tyr Tyr Ile Val Gln Glu Glu Lys Asn Tyr Arg Glu 
    130                 135                 140                 


Ser Leu Thr His Cys Arg Ile Arg Gly Gly Met Leu Ala Met Pro Lys 
145                 150                 155                 160 


Asp Glu Ala Ala Asn Thr Leu Ile Ala Asp Tyr Val Ala Lys Ser Gly 
                165                 170                 175     


Phe Phe Arg Val Phe Ile Gly Val Asn Asp Leu Glu Arg Glu Gly Gln 
            180                 185                 190         


Tyr Met Phe Thr Asp Asn Thr Pro Leu Gln Asn Tyr Ser Asn Trp Asn 
        195                 200                 205             


Glu Gly Glu Pro Ser Asp Pro Tyr Gly His Glu Asp Cys Val Glu Met 
    210                 215                 220                 


Leu Ser Ser Gly Arg Trp Asn Asp Thr Glu Cys His Leu Thr Met Tyr 
225                 230                 235                 240 


Phe Val Cys Glu Phe Ile Lys Lys Lys Lys 
                245                 250 


<210>  309
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  309

Gln Pro Ala Gly Asp Asp Ala Cys Ser Val Gln Ile Leu Val Pro Gly 
1               5                   10                  15      


Leu Lys Gly Asp Ala Gly Glu Lys Gly Asp Lys Gly Ala Pro Gly Arg 
            20                  25                  30          


Pro Gly Arg Val Gly Pro Thr Gly Glu Lys Gly Asp Met Gly Asp Lys 
        35                  40                  45              


Gly Gln Lys Gly Ser Val Gly Arg His Gly Lys Ile Gly Pro Ile Gly 
    50                  55                  60                  


Ser Lys Gly Glu Lys Gly Asp Ser Gly Asp Ile Gly Pro Pro Gly Pro 
65                  70                  75                  80  


Asn Gly Glu Pro Gly Leu Pro Cys Glu Cys Ser Gln Leu Arg Lys Ala 
                85                  90                  95      


Ile Gly Glu Met Asp Asn Gln Val Ser Gln Leu Thr Ser Glu Leu Lys 
            100                 105                 110         


Phe Ile Lys Asn Ala Val Ala Gly Val Arg Glu Thr Glu Ser Lys Ile 
        115                 120                 125             


Tyr Leu Leu Val Lys Glu Glu Lys Arg Tyr Ala Asp Ala Gln Leu Ser 
    130                 135                 140                 


Cys Gln Gly Arg Gly Gly Thr Leu Ser Met Pro Lys Asp Glu Ala Ala 
145                 150                 155                 160 


Asn Gly Leu Met Ala Ala Tyr Leu Ala Gln Ala Gly Leu Ala Arg Val 
                165                 170                 175     


Phe Ile Gly Ile Asn Asp Leu Glu Lys Glu Gly Ala Phe Val Tyr Ser 
            180                 185                 190         


Asp His Ser Pro Met Arg Thr Phe Asn Lys Trp Arg Ser Gly Glu Pro 
        195                 200                 205             


Asn Asn Ala Tyr Asp Glu Glu Asp Cys Val Glu Met Val Ala Ser Gly 
    210                 215                 220                 


Gly Trp Asn Asp Val Ala Cys His Thr Thr Met Tyr Phe Met Cys Glu 
225                 230                 235                 240 


Phe Asp Lys Glu Asn Met 
                245     


<210>  310
<211>  684
<212>  PRT
<213>  Homo Sapiens

<400>  310

Tyr Lys Val Val Glu Lys Met Asp Asn Val Thr Gly Gly Met Glu Thr 
1               5                   10                  15      


Ser Arg Gln Thr Tyr Asp Asp Lys Leu Thr Ala Val Glu Ser Asp Leu 
            20                  25                  30          


Glu Lys Leu Gly Asp Gln Thr Gly Lys Lys Ala Ile Ser Thr Asn Ser 
        35                  40                  45              


Glu Leu Ser Thr Phe Arg Ser Asp Ile Leu Asp Leu Arg Gln Gln Leu 
    50                  55                  60                  


Arg Glu Ile Thr Glu Lys Thr Ser Lys Asn Lys Asp Thr Leu Glu Lys 
65                  70                  75                  80  


Leu Gln Ala Ser Gly Asp Ala Leu Val Asp Arg Gln Ser Gln Leu Lys 
                85                  90                  95      


Glu Thr Leu Glu Asn Asn Ser Phe Leu Ile Thr Thr Val Asn Lys Thr 
            100                 105                 110         


Leu Gln Ala Tyr Asn Gly Tyr Val Thr Asn Leu Gln Gln Asp Thr Ser 
        115                 120                 125             


Val Leu Gln Gly Asn Leu Gln Asn Gln Met Tyr Ser His Asn Val Val 
    130                 135                 140                 


Ile Met Asn Leu Asn Asn Leu Asn Leu Thr Gln Val Gln Gln Arg Asn 
145                 150                 155                 160 


Leu Ile Thr Asn Leu Gln Arg Ser Val Asp Asp Thr Ser Gln Ala Ile 
                165                 170                 175     


Gln Arg Ile Lys Asn Asp Phe Gln Asn Leu Gln Gln Val Phe Leu Gln 
            180                 185                 190         


Ala Lys Lys Asp Thr Asp Trp Leu Lys Glu Lys Val Gln Ser Leu Gln 
        195                 200                 205             


Thr Leu Ala Ala Asn Asn Ser Ala Leu Ala Lys Ala Asn Asn Asp Thr 
    210                 215                 220                 


Leu Glu Asp Met Asn Ser Gln Leu Asn Ser Phe Thr Gly Gln Met Glu 
225                 230                 235                 240 


Asn Ile Thr Thr Ile Ser Gln Ala Asn Glu Gln Asn Leu Lys Asp Leu 
                245                 250                 255     


Gln Asp Leu His Lys Asp Ala Glu Asn Arg Thr Ala Ile Lys Phe Asn 
            260                 265                 270         


Gln Leu Glu Glu Arg Phe Gln Leu Phe Glu Thr Asp Ile Val Asn Ile 
        275                 280                 285             


Ile Ser Asn Ile Ser Tyr Thr Ala His His Leu Arg Thr Leu Thr Ser 
    290                 295                 300                 


Asn Leu Asn Glu Val Arg Thr Thr Cys Thr Asp Thr Leu Thr Lys His 
305                 310                 315                 320 


Thr Asp Asp Leu Thr Ser Leu Asn Asn Thr Leu Ala Asn Ile Arg Leu 
                325                 330                 335     


Asp Ser Val Ser Leu Arg Met Gln Gln Asp Leu Met Arg Ser Arg Leu 
            340                 345                 350         


Asp Thr Glu Val Ala Asn Leu Ser Val Ile Met Glu Glu Met Lys Leu 
        355                 360                 365             


Val Asp Ser Lys His Gly Gln Leu Ile Lys Asn Phe Thr Ile Leu Gln 
    370                 375                 380                 


Gly Pro Pro Gly Pro Arg Gly Pro Arg Gly Asp Arg Gly Ser Gln Gly 
385                 390                 395                 400 


Pro Pro Gly Pro Thr Gly Asn Lys Gly Gln Lys Gly Glu Lys Gly Glu 
                405                 410                 415     


Pro Gly Pro Pro Gly Pro Ala Gly Glu Arg Gly Pro Ile Gly Pro Ala 
            420                 425                 430         


Gly Pro Pro Gly Glu Arg Gly Gly Lys Gly Ser Lys Gly Ser Gln Gly 
        435                 440                 445             


Pro Lys Gly Ser Arg Gly Ser Pro Gly Lys Pro Gly Pro Gln Gly Pro 
    450                 455                 460                 


Ser Gly Asp Pro Gly Pro Pro Gly Pro Pro Gly Lys Glu Gly Leu Pro 
465                 470                 475                 480 


Gly Pro Gln Gly Pro Pro Gly Phe Gln Gly Leu Gln Gly Thr Val Gly 
                485                 490                 495     


Glu Pro Gly Val Pro Gly Pro Arg Gly Leu Pro Gly Leu Pro Gly Val 
            500                 505                 510         


Pro Gly Met Pro Gly Pro Lys Gly Pro Pro Gly Pro Pro Gly Pro Ser 
        515                 520                 525             


Gly Ala Val Val Pro Leu Ala Leu Gln Asn Glu Pro Thr Pro Ala Pro 
    530                 535                 540                 


Glu Asp Asn Ser Cys Pro Pro His Trp Lys Asn Phe Thr Asp Lys Cys 
545                 550                 555                 560 


Tyr Tyr Phe Ser Val Glu Lys Glu Ile Phe Glu Asp Ala Lys Leu Phe 
                565                 570                 575     


Cys Glu Asp Lys Ser Ser His Leu Val Phe Ile Asn Thr Arg Glu Glu 
            580                 585                 590         


Gln Gln Trp Ile Lys Lys Gln Met Val Gly Arg Glu Ser His Trp Ile 
        595                 600                 605             


Gly Leu Thr Asp Ser Glu Arg Glu Asn Glu Trp Lys Trp Leu Asp Gly 
    610                 615                 620                 


Thr Ser Pro Asp Tyr Lys Asn Trp Lys Ala Gly Gln Pro Asp Asn Trp 
625                 630                 635                 640 


Gly His Gly His Gly Pro Gly Glu Asp Cys Ala Gly Leu Ile Tyr Ala 
                645                 650                 655     


Gly Gln Trp Asn Asp Phe Gln Cys Glu Asp Val Asn Asn Phe Ile Cys 
            660                 665                 670         


Glu Lys Asp Arg Glu Thr Val Leu Ser Ser Ala Leu 
        675                 680                 


<210>  311
<211>  737
<212>  PRT
<213>  Homo Sapiens

<400>  311

Gln Gly Gln Ser Pro Leu Gly Ser Asp Leu Gly Pro Gln Met Leu Arg 
1               5                   10                  15      


Glu Leu Gln Glu Thr Asn Ala Ala Leu Gln Asp Val Arg Glu Leu Leu 
            20                  25                  30          


Arg Gln Gln Val Arg Glu Ile Thr Phe Leu Lys Asn Thr Val Met Glu 
        35                  40                  45              


Cys Asp Ala Cys Gly Met Gln Gln Ser Val Arg Thr Gly Leu Pro Ser 
    50                  55                  60                  


Val Arg Pro Leu Leu His Cys Ala Pro Gly Phe Cys Phe Pro Gly Val 
65                  70                  75                  80  


Ala Cys Ile Gln Thr Glu Ser Gly Ala Arg Cys Gly Pro Cys Pro Ala 
                85                  90                  95      


Gly Phe Thr Gly Asn Gly Ser His Cys Thr Asp Val Asn Glu Cys Asn 
            100                 105                 110         


Ala His Pro Cys Phe Pro Arg Val Arg Cys Ile Asn Thr Ser Pro Gly 
        115                 120                 125             


Phe Arg Cys Glu Ala Cys Pro Pro Gly Tyr Ser Gly Pro Thr His Gln 
    130                 135                 140                 


Gly Val Gly Leu Ala Phe Ala Lys Ala Asn Lys Gln Val Cys Thr Asp 
145                 150                 155                 160 


Ile Asn Glu Cys Glu Thr Gly Gln His Asn Cys Val Pro Asn Ser Val 
                165                 170                 175     


Cys Ile Asn Thr Arg Gly Ser Phe Gln Cys Gly Pro Cys Gln Pro Gly 
            180                 185                 190         


Phe Val Gly Asp Gln Ala Ser Gly Cys Gln Arg Arg Ala Gln Arg Phe 
        195                 200                 205             


Cys Pro Asp Gly Ser Pro Ser Glu Cys His Glu His Ala Asp Cys Val 
    210                 215                 220                 


Leu Glu Arg Asp Gly Ser Arg Ser Cys Val Cys Ala Val Gly Trp Ala 
225                 230                 235                 240 


Gly Asn Gly Ile Leu Cys Gly Arg Asp Thr Asp Leu Asp Gly Phe Pro 
                245                 250                 255     


Asp Glu Lys Leu Arg Cys Pro Glu Arg Gln Cys Arg Lys Asp Asn Cys 
            260                 265                 270         


Val Thr Val Pro Asn Ser Gly Gln Glu Asp Val Asp Arg Asp Gly Ile 
        275                 280                 285             


Gly Asp Ala Cys Asp Pro Asp Ala Asp Gly Asp Gly Val Pro Asn Glu 
    290                 295                 300                 


Lys Asp Asn Cys Pro Leu Val Arg Asn Pro Asp Gln Arg Asn Thr Asp 
305                 310                 315                 320 


Glu Asp Lys Trp Gly Asp Ala Cys Asp Asn Cys Arg Ser Gln Lys Asn 
                325                 330                 335     


Asp Asp Gln Lys Asp Thr Asp Gln Asp Gly Arg Gly Asp Ala Cys Asp 
            340                 345                 350         


Asp Asp Ile Asp Gly Asp Arg Ile Arg Asn Gln Ala Asp Asn Cys Pro 
        355                 360                 365             


Arg Val Pro Asn Ser Asp Gln Lys Asp Ser Asp Gly Asp Gly Ile Gly 
    370                 375                 380                 


Asp Ala Cys Asp Asn Cys Pro Gln Lys Ser Asn Pro Asp Gln Ala Asp 
385                 390                 395                 400 


Val Asp His Asp Phe Val Gly Asp Ala Cys Asp Ser Asp Gln Asp Gln 
                405                 410                 415     


Asp Gly Asp Gly His Gln Asp Ser Arg Asp Asn Cys Pro Thr Val Pro 
            420                 425                 430         


Asn Ser Ala Gln Glu Asp Ser Asp His Asp Gly Gln Gly Asp Ala Cys 
        435                 440                 445             


Asp Asp Asp Asp Asp Asn Asp Gly Val Pro Asp Ser Arg Asp Asn Cys 
    450                 455                 460                 


Arg Leu Val Pro Asn Pro Gly Gln Glu Asp Ala Asp Arg Asp Gly Val 
465                 470                 475                 480 


Gly Asp Val Cys Gln Asp Asp Phe Asp Ala Asp Lys Val Val Asp Lys 
                485                 490                 495     


Ile Asp Val Cys Pro Glu Asn Ala Glu Val Thr Leu Thr Asp Phe Arg 
            500                 505                 510         


Ala Phe Gln Thr Val Val Leu Asp Pro Glu Gly Asp Ala Gln Ile Asp 
        515                 520                 525             


Pro Asn Trp Val Val Leu Asn Gln Gly Arg Glu Ile Val Gln Thr Met 
    530                 535                 540                 


Asn Ser Asp Pro Gly Leu Ala Val Gly Tyr Thr Ala Phe Asn Gly Val 
545                 550                 555                 560 


Asp Phe Glu Gly Thr Phe His Val Asn Thr Val Thr Asp Asp Asp Tyr 
                565                 570                 575     


Ala Gly Phe Ile Phe Gly Tyr Gln Asp Ser Ser Ser Phe Tyr Val Val 
            580                 585                 590         


Met Trp Lys Gln Met Glu Gln Thr Tyr Trp Gln Ala Asn Pro Phe Arg 
        595                 600                 605             


Ala Val Ala Glu Pro Gly Ile Gln Leu Lys Ala Val Lys Ser Ser Thr 
    610                 615                 620                 


Gly Pro Gly Glu Gln Leu Arg Asn Ala Leu Trp His Thr Gly Asp Thr 
625                 630                 635                 640 


Glu Ser Gln Val Arg Leu Leu Trp Lys Asp Pro Arg Asn Val Gly Trp 
                645                 650                 655     


Lys Asp Lys Lys Ser Tyr Arg Trp Phe Leu Gln His Arg Pro Gln Val 
            660                 665                 670         


Gly Tyr Ile Arg Val Arg Phe Tyr Glu Gly Pro Glu Leu Val Ala Asp 
        675                 680                 685             


Ser Asn Val Val Leu Asp Thr Thr Met Arg Gly Gly Arg Leu Gly Val 
    690                 695                 700                 


Phe Cys Phe Ser Gln Glu Asn Ile Ile Trp Ala Asn Leu Arg Tyr Arg 
705                 710                 715                 720 


Cys Asn Asp Thr Ile Pro Glu Asp Tyr Glu Thr His Gln Leu Arg Gln 
                725                 730                 735     


Ala 
    


<210>  312
<211>  432
<212>  PRT
<213>  Homo Sapiens

<400>  312

Ala Gln Pro Gln Ala Pro Gly Tyr Leu Ile Ala Ala Pro Ser Val Phe 
1               5                   10                  15      


Arg Ala Gly Val Glu Glu Val Ile Ser Val Thr Ile Phe Asn Ser Pro 
            20                  25                  30          


Arg Glu Val Thr Val Gln Ala Gln Leu Val Ala Gln Gly Glu Pro Val 
        35                  40                  45              


Val Gln Ser Gln Gly Ala Ile Leu Asp Lys Gly Thr Ile Lys Leu Lys 
    50                  55                  60                  


Val Pro Thr Gly Leu Arg Gly Gln Ala Leu Leu Lys Val Trp Gly Arg 
65                  70                  75                  80  


Gly Trp Gln Ala Glu Glu Gly Pro Leu Phe His Asn Gln Thr Ser Val 
                85                  90                  95      


Thr Val Asp Gly Arg Gly Ala Ser Val Phe Ile Gln Thr Asp Lys Pro 
            100                 105                 110         


Val Tyr Arg Pro Gln His Arg Val Leu Ile Ser Ile Phe Thr Val Ser 
        115                 120                 125             


Pro Asn Leu Arg Pro Val Asn Glu Lys Leu Glu Ala Tyr Ile Leu Asp 
    130                 135                 140                 


Pro Arg Gly Ser Arg Met Ile Glu Trp Arg His Leu Lys Pro Phe Cys 
145                 150                 155                 160 


Cys Gly Ile Thr Asn Met Ser Phe Pro Leu Ser Asp Gln Pro Val Leu 
                165                 170                 175     


Gly Glu Trp Phe Ile Phe Val Glu Met Gln Gly His Ala Tyr Asn Lys 
            180                 185                 190         


Ser Phe Glu Val Gln Lys Tyr Val Leu Pro Lys Phe Glu Leu Leu Ile 
        195                 200                 205             


Asp Pro Pro Arg Tyr Ile Gln Asp Leu Asp Ala Cys Glu Thr Gly Thr 
    210                 215                 220                 


Val Arg Ala Arg Tyr Thr Phe Gly Lys Pro Val Ala Gly Ala Leu Thr 
225                 230                 235                 240 


Ile Asn Met Thr Val Asn Gly Val Gly Tyr Tyr Ser His Glu Val Gly 
                245                 250                 255     


Arg Pro Val Leu Arg Thr Thr Lys Ile Leu Gly Ser Gln Asp Phe Asp 
            260                 265                 270         


Ile Cys Val Arg Asp Met Ile Pro Ala Asp Val Pro Glu His Phe Arg 
        275                 280                 285             


Gly Arg Val Ser Ile Trp Ala Met Val Thr Ser Val Asp Gly Ser Gln 
    290                 295                 300                 


Gln Val Ala Phe Asp Asp Ser Thr Pro Val Gln Arg Gln Leu Val Asp 
305                 310                 315                 320 


Ile Arg Tyr Ser Lys Asp Thr Arg Lys Gln Phe Lys Pro Gly Leu Ala 
                325                 330                 335     


Tyr Val Gly Lys Val Glu Leu Ser Tyr Pro Asp Gly Ser Pro Ala Glu 
            340                 345                 350         


Gly Val Thr Val Gln Ile Lys Ala Glu Leu Thr Pro Lys Asp Asn Ile 
        355                 360                 365             


Tyr Thr Ser Glu Val Val Ser Gln Arg Gly Leu Val Gly Phe Glu Ile 
    370                 375                 380                 


Pro Ser Ile Pro Thr Ser Ala Gln His Val Trp Leu Glu Val Phe Gln 
385                 390                 395                 400 


Glu Leu Glu Asp Tyr Asp Val Ser Asp Ser Phe Gly Val Ser Arg Glu 
                405                 410                 415     


Asp Gly Pro Phe Trp Trp Ala Gly Leu Thr Ala Gln Arg Arg Arg Arg 
            420                 425                 430         


<210>  313
<211>  524
<212>  PRT
<213>  Homo Sapiens

<400>  313

Cys Pro Met Gly Cys Asp Cys Phe Val Gln Glu Val Phe Cys Ser Asp 
1               5                   10                  15      


Glu Glu Leu Ala Thr Val Pro Leu Asp Ile Pro Pro Tyr Thr Lys Asn 
            20                  25                  30          


Ile Ile Phe Val Glu Thr Ser Phe Thr Thr Leu Glu Thr Arg Ala Phe 
        35                  40                  45              


Gly Ser Asn Pro Asn Leu Thr Lys Val Val Phe Leu Asn Thr Gln Leu 
    50                  55                  60                  


Cys Gln Phe Arg Pro Asp Ala Phe Gly Gly Leu Pro Arg Leu Glu Asp 
65                  70                  75                  80  


Leu Glu Val Thr Gly Ser Ser Phe Leu Asn Leu Ser Thr Asn Ile Phe 
                85                  90                  95      


Ser Asn Leu Thr Ser Leu Gly Lys Leu Thr Leu Asn Phe Asn Met Leu 
            100                 105                 110         


Glu Ala Leu Pro Glu Gly Leu Phe Gln His Leu Ala Ala Leu Glu Ser 
        115                 120                 125             


Leu His Leu Gln Gly Asn Gln Leu Gln Ala Leu Pro Arg Arg Leu Phe 
    130                 135                 140                 


Gln Pro Leu Thr His Leu Lys Thr Leu Asn Leu Ala Gln Asn Leu Leu 
145                 150                 155                 160 


Ala Gln Leu Pro Glu Glu Leu Phe His Pro Leu Thr Ser Leu Gln Thr 
                165                 170                 175     


Leu Lys Leu Ser Asn Asn Ala Leu Ser Gly Leu Pro Gln Gly Val Phe 
            180                 185                 190         


Gly Lys Leu Gly Ser Leu Gln Glu Leu Phe Leu Asp Ser Asn Asn Ile 
        195                 200                 205             


Ser Glu Leu Pro Pro Gln Val Phe Ser Gln Leu Phe Cys Leu Glu Arg 
    210                 215                 220                 


Leu Trp Leu Gln Arg Asn Ala Ile Thr His Leu Pro Leu Ser Ile Phe 
225                 230                 235                 240 


Ala Ser Leu Gly Asn Leu Thr Phe Leu Ser Leu Gln Trp Asn Met Leu 
                245                 250                 255     


Arg Val Leu Pro Ala Gly Leu Phe Ala His Thr Pro Cys Leu Val Gly 
            260                 265                 270         


Leu Ser Leu Thr His Asn Gln Leu Glu Thr Val Ala Glu Gly Thr Phe 
        275                 280                 285             


Ala His Leu Ser Asn Leu Arg Ser Leu Met Leu Ser Tyr Asn Ala Ile 
    290                 295                 300                 


Thr His Leu Pro Ala Gly Ile Phe Arg Asp Leu Glu Glu Leu Val Lys 
305                 310                 315                 320 


Leu Tyr Leu Gly Ser Asn Asn Leu Thr Ala Leu His Pro Ala Leu Phe 
                325                 330                 335     


Gln Asn Leu Ser Lys Leu Glu Leu Leu Ser Leu Ser Lys Asn Gln Leu 
            340                 345                 350         


Thr Thr Leu Pro Glu Gly Ile Phe Asp Thr Asn Tyr Asn Leu Phe Asn 
        355                 360                 365             


Leu Ala Leu His Gly Asn Pro Trp Gln Cys Asp Cys His Leu Ala Tyr 
    370                 375                 380                 


Leu Phe Asn Trp Leu Gln Gln Tyr Thr Asp Arg Leu Leu Asn Ile Gln 
385                 390                 395                 400 


Thr Tyr Cys Ala Gly Pro Ala Tyr Leu Lys Gly Gln Val Val Pro Ala 
                405                 410                 415     


Leu Asn Glu Lys Gln Leu Val Cys Pro Val Thr Arg Asp His Leu Gly 
            420                 425                 430         


Phe Gln Val Thr Trp Pro Asp Glu Ser Lys Ala Gly Gly Ser Trp Asp 
        435                 440                 445             


Leu Ala Val Gln Glu Arg Ala Ala Arg Ser Gln Cys Thr Tyr Ser Asn 
    450                 455                 460                 


Pro Glu Gly Thr Val Val Leu Ala Cys Asp Gln Ala Gln Cys Arg Trp 
465                 470                 475                 480 


Leu Asn Val Gln Leu Ser Pro Trp Gln Gly Ser Leu Gly Leu Gln Tyr 
                485                 490                 495     


Asn Ala Ser Gln Glu Trp Asp Leu Arg Ser Ser Cys Gly Ser Leu Arg 
            500                 505                 510         


Leu Thr Val Ser Ile Glu Ala Arg Ala Ala Gly Pro 
        515                 520                 


<210>  314
<211>  1322
<212>  PRT
<213>  Homo Sapiens

<400>  314

Phe Cys Asn Lys Asn Asn Thr Arg Cys Leu Ser Asn Ser Cys Gln Asn 
1               5                   10                  15      


Asn Ser Thr Cys Lys Asp Phe Ser Lys Asp Asn Asp Cys Ser Cys Ser 
            20                  25                  30          


Asp Thr Ala Asn Asn Leu Asp Lys Asp Cys Asp Asn Met Lys Asp Pro 
        35                  40                  45              


Cys Phe Ser Asn Pro Cys Gln Gly Ser Ala Thr Cys Val Asn Thr Pro 
    50                  55                  60                  


Gly Glu Arg Ser Phe Leu Cys Lys Cys Pro Pro Gly Tyr Ser Gly Thr 
65                  70                  75                  80  


Ile Cys Glu Thr Thr Ile Gly Ser Cys Gly Lys Asn Ser Cys Gln His 
                85                  90                  95      


Gly Gly Ile Cys His Gln Asp Pro Ile Tyr Pro Val Cys Ile Cys Pro 
            100                 105                 110         


Ala Gly Tyr Ala Gly Arg Phe Cys Glu Ile Asp His Asp Glu Cys Ala 
        115                 120                 125             


Ser Ser Pro Cys Gln Asn Gly Ala Val Cys Gln Asp Gly Ile Asp Gly 
    130                 135                 140                 


Tyr Ser Cys Phe Cys Val Pro Gly Tyr Gln Gly Arg His Cys Asp Leu 
145                 150                 155                 160 


Glu Val Asp Glu Cys Ala Ser Asp Pro Cys Lys Asn Glu Ala Thr Cys 
                165                 170                 175     


Leu Asn Glu Ile Gly Arg Tyr Thr Cys Ile Cys Pro His Asn Tyr Ser 
            180                 185                 190         


Gly Val Asn Cys Glu Leu Glu Ile Asp Glu Cys Trp Ser Gln Pro Cys 
        195                 200                 205             


Leu Asn Gly Ala Thr Cys Gln Asp Ala Leu Gly Ala Tyr Phe Cys Asp 
    210                 215                 220                 


Cys Ala Pro Gly Phe Leu Gly Asp His Cys Glu Leu Asn Thr Asp Glu 
225                 230                 235                 240 


Cys Ala Ser Gln Pro Cys Leu His Gly Gly Leu Cys Val Asp Gly Glu 
                245                 250                 255     


Asn Arg Tyr Ser Cys Asn Cys Thr Gly Ser Gly Phe Thr Gly Thr His 
            260                 265                 270         


Cys Glu Thr Leu Met Pro Leu Cys Trp Ser Lys Pro Cys His Asn Asn 
        275                 280                 285             


Ala Thr Cys Glu Asp Ser Val Asp Asn Tyr Thr Cys His Cys Trp Pro 
    290                 295                 300                 


Gly Tyr Thr Gly Ala Gln Cys Glu Ile Asp Leu Asn Glu Cys Asn Ser 
305                 310                 315                 320 


Asn Pro Cys Gln Ser Asn Gly Glu Cys Val Glu Leu Ser Ser Glu Lys 
                325                 330                 335     


Gln Tyr Gly Arg Ile Thr Gly Leu Pro Ser Ser Phe Ser Tyr His Glu 
            340                 345                 350         


Ala Ser Gly Tyr Val Cys Ile Cys Gln Pro Gly Phe Thr Gly Ile His 
        355                 360                 365             


Cys Glu Glu Asp Val Asn Glu Cys Ser Ser Asn Pro Cys Gln Asn Gly 
    370                 375                 380                 


Gly Thr Cys Glu Asn Leu Pro Gly Asn Tyr Thr Cys His Cys Pro Phe 
385                 390                 395                 400 


Asp Asn Leu Ser Arg Thr Phe Tyr Gly Gly Arg Asp Cys Ser Asp Ile 
                405                 410                 415     


Leu Leu Gly Cys Thr His Gln Gln Cys Leu Asn Asn Gly Thr Cys Ile 
            420                 425                 430         


Pro His Phe Gln Asp Gly Gln His Gly Phe Ser Cys Leu Cys Pro Ser 
        435                 440                 445             


Gly Tyr Thr Gly Ser Leu Cys Glu Ile Ala Thr Thr Leu Ser Phe Glu 
    450                 455                 460                 


Gly Asp Gly Phe Leu Trp Val Lys Ser Gly Ser Val Thr Thr Lys Gly 
465                 470                 475                 480 


Ser Val Cys Asn Ile Ala Leu Arg Phe Gln Thr Val Gln Pro Met Ala 
                485                 490                 495     


Leu Leu Leu Phe Arg Ser Asn Arg Asp Val Phe Val Lys Leu Glu Leu 
            500                 505                 510         


Leu Ser Gly Tyr Ile His Leu Ser Ile Gln Val Asn Asn Gln Ser Lys 
        515                 520                 525             


Val Leu Leu Phe Ile Ser His Asn Thr Ser Asp Gly Glu Trp His Phe 
    530                 535                 540                 


Val Glu Val Ile Phe Ala Glu Ala Val Thr Leu Thr Leu Ile Asp Asp 
545                 550                 555                 560 


Ser Cys Lys Glu Lys Cys Ile Ala Lys Ala Pro Thr Pro Leu Glu Ser 
                565                 570                 575     


Asp Gln Ser Ile Cys Ala Phe Gln Asn Ser Phe Leu Gly Gly Leu Pro 
            580                 585                 590         


Val Gly Met Thr Ser Asn Gly Val Ala Leu Leu Asn Phe Tyr Asn Met 
        595                 600                 605             


Pro Ser Thr Pro Ser Phe Val Gly Cys Leu Gln Asp Ile Lys Ile Asp 
    610                 615                 620                 


Trp Asn His Ile Thr Leu Glu Asn Ile Ser Ser Gly Ser Ser Leu Asn 
625                 630                 635                 640 


Val Lys Ala Gly Cys Val Arg Lys Asp Trp Cys Glu Ser Gln Pro Cys 
                645                 650                 655     


Gln Ser Arg Gly Arg Cys Ile Asn Leu Trp Leu Ser Tyr Gln Cys Asp 
            660                 665                 670         


Cys His Arg Pro Tyr Glu Gly Pro Asn Cys Leu Arg Glu Tyr Val Ala 
        675                 680                 685             


Gly Arg Phe Gly Gln Asp Asp Ser Thr Gly Tyr Val Ile Phe Thr Leu 
    690                 695                 700                 


Asp Glu Ser Tyr Gly Asp Thr Ile Ser Leu Ser Met Phe Val Arg Thr 
705                 710                 715                 720 


Leu Gln Pro Ser Gly Leu Leu Leu Ala Leu Glu Asn Ser Thr Tyr Gln 
                725                 730                 735     


Tyr Ile Arg Val Trp Leu Glu Arg Gly Arg Leu Ala Met Leu Thr Pro 
            740                 745                 750         


Asn Ser Pro Lys Leu Val Val Lys Phe Val Leu Asn Asp Gly Asn Val 
        755                 760                 765             


His Leu Ile Ser Leu Lys Ile Lys Pro Tyr Lys Ile Glu Leu Tyr Gln 
    770                 775                 780                 


Ser Ser Gln Asn Leu Gly Phe Ile Ser Ala Ser Thr Trp Lys Ile Glu 
785                 790                 795                 800 


Lys Gly Asp Val Ile Tyr Ile Gly Gly Leu Pro Asp Lys Gln Glu Thr 
                805                 810                 815     


Glu Leu Asn Gly Gly Phe Phe Lys Gly Cys Ile Gln Asp Val Arg Leu 
            820                 825                 830         


Asn Asn Gln Asn Leu Glu Phe Phe Pro Asn Pro Thr Asn Asn Ala Ser 
        835                 840                 845             


Leu Asn Pro Val Leu Val Asn Val Thr Gln Gly Cys Ala Gly Asp Asn 
    850                 855                 860                 


Ser Cys Lys Ser Asn Pro Cys His Asn Gly Gly Val Cys His Ser Arg 
865                 870                 875                 880 


Trp Asp Asp Phe Ser Cys Ser Cys Pro Ala Leu Thr Ser Gly Lys Ala 
                885                 890                 895     


Cys Glu Glu Val Gln Trp Cys Gly Phe Ser Pro Cys Pro His Gly Ala 
            900                 905                 910         


Gln Cys Gln Pro Val Leu Gln Gly Phe Glu Cys Ile Ala Asn Ala Val 
        915                 920                 925             


Phe Asn Gly Gln Ser Gly Gln Ile Leu Phe Arg Ser Asn Gly Asn Ile 
    930                 935                 940                 


Thr Arg Glu Leu Thr Asn Ile Thr Phe Gly Phe Arg Thr Arg Asp Ala 
945                 950                 955                 960 


Asn Val Ile Ile Leu His Ala Glu Lys Glu Pro Glu Phe Leu Asn Ile 
                965                 970                 975     


Ser Ile Gln Asp Ser Arg Leu Phe Phe Gln Leu Gln Ser Gly Asn Ser 
            980                 985                 990         


Phe Tyr Met Leu Ser Leu Thr Ser  Leu Gln Ser Val Asn  Asp Gly Thr 
        995                 1000                 1005             


Trp His  Glu Val Thr Leu Ser  Met Thr Asp Pro Leu  Ser Gln Thr 
    1010                 1015                 1020             


Ser Arg  Trp Gln Met Glu Val  Asp Asn Glu Thr Pro  Phe Val Thr 
    1025                 1030                 1035             


Ser Thr  Ile Ala Thr Gly Ser  Leu Asn Phe Leu Lys  Asp Asn Thr 
    1040                 1045                 1050             


Asp Ile  Tyr Val Gly Asp Arg  Ala Ile Asp Asn Ile  Lys Gly Leu 
    1055                 1060                 1065             


Gln Gly  Cys Leu Ser Thr Ile  Glu Ile Gly Gly Ile  Tyr Leu Ser 
    1070                 1075                 1080             


Tyr Phe  Glu Asn Val His Gly  Phe Ile Asn Lys Pro  Gln Glu Glu 
    1085                 1090                 1095             


Gln Phe  Leu Lys Ile Ser Thr  Asn Ser Val Val Thr  Gly Cys Leu 
    1100                 1105                 1110             


Gln Leu  Asn Val Cys Asn Ser  Asn Pro Cys Leu His  Gly Gly Asn 
    1115                 1120                 1125             


Cys Glu  Asp Ile Tyr Ser Ser  Tyr His Cys Ser Cys  Pro Leu Gly 
    1130                 1135                 1140             


Trp Ser  Gly Lys His Cys Glu  Leu Asn Ile Asp Glu  Cys Phe Ser 
    1145                 1150                 1155             


Asn Pro  Cys Ile His Gly Asn  Cys Ser Asp Arg Val  Ala Ala Tyr 
    1160                 1165                 1170             


His Cys  Thr Cys Glu Pro Gly  Tyr Thr Gly Val Asn  Cys Glu Val 
    1175                 1180                 1185             


Asp Ile  Asp Asn Cys Gln Ser  His Gln Cys Ala Asn  Gly Ala Thr 
    1190                 1195                 1200             


Cys Ile  Ser His Thr Asn Gly  Tyr Ser Cys Leu Cys  Phe Gly Asn 
    1205                 1210                 1215             


Phe Thr  Gly Lys Phe Cys Arg  Gln Ser Arg Leu Pro  Ser Thr Val 
    1220                 1225                 1230             


Cys Gly  Asn Glu Lys Thr Asn  Leu Thr Cys Tyr Asn  Gly Gly Asn 
    1235                 1240                 1245             


Cys Thr  Glu Phe Gln Thr Glu  Leu Lys Cys Met Cys  Arg Pro Gly 
    1250                 1255                 1260             


Phe Thr  Gly Glu Trp Cys Glu  Lys Asp Ile Asp Glu  Cys Ala Ser 
    1265                 1270                 1275             


Asp Pro  Cys Val Asn Gly Gly  Leu Cys Gln Asp Leu  Leu Asn Lys 
    1280                 1285                 1290             


Phe Gln  Cys Leu Cys Asp Val  Ala Phe Ala Gly Glu  Arg Cys Glu 
    1295                 1300                 1305             


Val Asp  Leu Ala Asp Asp Leu  Ile Ser Asp Ile Phe  Thr Thr 
    1310                 1315                 1320         


<210>  315
<211>  393
<212>  PRT
<213>  Homo Sapiens

<400>  315

Gln Pro Ser Pro Pro Pro Gln Ser Ser Pro Pro Pro Gln Pro His Pro 
1               5                   10                  15      


Cys His Thr Cys Arg Gly Leu Val Asp Ser Phe Asn Lys Gly Leu Glu 
            20                  25                  30          


Arg Thr Ile Arg Asp Asn Phe Gly Gly Gly Asn Thr Ala Trp Glu Glu 
        35                  40                  45              


Glu Asn Leu Ser Lys Tyr Lys Asp Ser Glu Thr Arg Leu Val Glu Val 
    50                  55                  60                  


Leu Glu Gly Val Cys Ser Lys Ser Asp Phe Glu Cys His Arg Leu Leu 
65                  70                  75                  80  


Glu Leu Ser Glu Glu Leu Val Glu Ser Trp Trp Phe His Lys Gln Gln 
                85                  90                  95      


Glu Ala Pro Asp Leu Phe Gln Trp Leu Cys Ser Asp Ser Leu Lys Leu 
            100                 105                 110         


Cys Cys Pro Ala Gly Thr Phe Gly Pro Ser Cys Leu Pro Cys Pro Gly 
        115                 120                 125             


Gly Thr Glu Arg Pro Cys Gly Gly Tyr Gly Gln Cys Glu Gly Glu Gly 
    130                 135                 140                 


Thr Arg Gly Gly Ser Gly His Cys Asp Cys Gln Ala Gly Tyr Gly Gly 
145                 150                 155                 160 


Glu Ala Cys Gly Gln Cys Gly Leu Gly Tyr Phe Glu Ala Glu Arg Asn 
                165                 170                 175     


Ala Ser His Leu Val Cys Ser Ala Cys Phe Gly Pro Cys Ala Arg Cys 
            180                 185                 190         


Ser Gly Pro Glu Glu Ser Asn Cys Leu Gln Cys Lys Lys Gly Trp Ala 
        195                 200                 205             


Leu His His Leu Lys Cys Val Asp Ile Asp Glu Cys Gly Thr Glu Gly 
    210                 215                 220                 


Ala Asn Cys Gly Ala Asp Gln Phe Cys Val Asn Thr Glu Gly Ser Tyr 
225                 230                 235                 240 


Glu Cys Arg Asp Cys Ala Lys Ala Cys Leu Gly Cys Met Gly Ala Gly 
                245                 250                 255     


Pro Gly Arg Cys Lys Lys Cys Ser Pro Gly Tyr Gln Gln Val Gly Ser 
            260                 265                 270         


Lys Cys Leu Asp Val Asp Glu Cys Glu Thr Glu Val Cys Pro Gly Glu 
        275                 280                 285             


Asn Lys Gln Cys Glu Asn Thr Glu Gly Gly Tyr Arg Cys Ile Cys Ala 
    290                 295                 300                 


Glu Gly Tyr Lys Gln Met Glu Gly Ile Cys Val Lys Glu Gln Ile Pro 
305                 310                 315                 320 


Gly Ala Phe Pro Ile Leu Thr Asp Leu Thr Pro Glu Thr Thr Arg Arg 
                325                 330                 335     


Trp Lys Leu Gly Ser His Pro His Ser Thr Tyr Val Lys Met Lys Met 
            340                 345                 350         


Gln Arg Asp Glu Ala Thr Phe Pro Gly Leu Tyr Gly Lys Gln Val Ala 
        355                 360                 365             


Lys Leu Gly Ser Gln Ser Arg Gln Ser Asp Arg Gly Thr Arg Leu Ile 
    370                 375                 380                 


His Ser Gln Gln Ala Ser Ser Gln Arg 
385                 390             


<210>  316
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  316

Ala Lys Lys Pro Thr Pro Cys His Arg Cys Arg Gly Leu Val Asp Lys 
1               5                   10                  15      


Phe Asn Gln Gly Met Val Asp Thr Ala Lys Lys Asn Phe Gly Gly Gly 
            20                  25                  30          


Asn Thr Ala Trp Glu Glu Lys Thr Leu Ser Lys Tyr Glu Ser Ser Glu 
        35                  40                  45              


Ile Arg Leu Leu Glu Ile Leu Glu Gly Leu Cys Glu Ser Ser Asp Phe 
    50                  55                  60                  


Glu Cys Asn Gln Met Leu Glu Ala Gln Glu Glu His Leu Glu Ala Trp 
65                  70                  75                  80  


Trp Leu Gln Leu Lys Ser Glu Tyr Pro Asp Leu Phe Glu Trp Phe Cys 
                85                  90                  95      


Val Lys Thr Leu Lys Val Cys Cys Ser Pro Gly Thr Tyr Gly Pro Asp 
            100                 105                 110         


Cys Leu Ala Cys Gln Gly Gly Ser Gln Arg Pro Cys Ser Gly Asn Gly 
        115                 120                 125             


His Cys Ser Gly Asp Gly Ser Arg Gln Gly Asp Gly Ser Cys Arg Cys 
    130                 135                 140                 


His Met Gly Tyr Gln Gly Pro Leu Cys Thr Asp Cys Met Asp Gly Tyr 
145                 150                 155                 160 


Phe Ser Ser Leu Arg Asn Glu Thr His Ser Ile Cys Thr Ala Cys Asp 
                165                 170                 175     


Glu Ser Cys Lys Thr Cys Ser Gly Leu Thr Asn Arg Asp Cys Gly Glu 
            180                 185                 190         


Cys Glu Val Gly Trp Val Leu Asp Glu Gly Ala Cys Val Asp Val Asp 
        195                 200                 205             


Glu Cys Ala Ala Glu Pro Pro Pro Cys Ser Ala Ala Gln Phe Cys Lys 
    210                 215                 220                 


Asn Ala Asn Gly Ser Tyr Thr Cys Glu Glu Cys Asp Ser Ser Cys Val 
225                 230                 235                 240 


Gly Cys Thr Gly Glu Gly Pro Gly Asn Cys Lys Glu Cys Ile Ser Gly 
                245                 250                 255     


Tyr Ala Arg Glu His Gly Gln Cys Ala Asp Val Asp Glu Cys Ala Leu 
            260                 265                 270         


Ala Glu Lys Thr Cys Val Arg Lys Asn Glu Asn Cys Tyr Asn Thr Pro 
        275                 280                 285             


Gly Ser Tyr Val Cys Val Cys Pro Asp Gly Phe Glu Gly Thr Glu Asp 
    290                 295                 300                 


Ala Cys Val Pro Pro Ala Glu Ala Glu Ala Thr Glu Gly Glu Ser Pro 
305                 310                 315                 320 


Thr Gln Leu Pro Ser Arg Glu Asp Leu 
                325                 


<210>  317
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  317

Ala His Thr Ala Val Ile Ser Pro Gln Asp Pro Thr Leu Leu Ile Gly 
1               5                   10                  15      


Ser Ser Leu Leu Ala Thr Cys Ser Val His Gly Asp Pro Pro Gly Ala 
            20                  25                  30          


Thr Ala Glu Gly Leu Tyr Trp Thr Leu Asn Gly Arg Arg Leu Pro Pro 
        35                  40                  45              


Glu Leu Ser Arg Val Leu Asn Ala Ser Thr Leu Ala Leu Ala Leu Ala 
    50                  55                  60                  


Asn Leu Asn Gly Ser Arg Gln Arg Ser Gly Asp Asn Leu Val Cys His 
65                  70                  75                  80  


Ala Arg Asp Gly Ser Ile Leu Ala Gly Ser Cys Leu Tyr Val Gly Leu 
                85                  90                  95      


Pro Pro Glu Lys Pro Val Asn Ile Ser Cys Trp Ser Lys Asn Met Lys 
            100                 105                 110         


Asp Leu Thr Cys Arg Trp Thr Pro Gly Ala His Gly Glu Thr Phe Leu 
        115                 120                 125             


His Thr Asn Tyr Ser Leu Lys Tyr Lys Leu Arg Trp Tyr Gly Gln Asp 
    130                 135                 140                 


Asn Thr Cys Glu Glu Tyr His Thr Val Gly Pro His Ser Cys His Ile 
145                 150                 155                 160 


Pro Lys Asp Leu Ala Leu Phe Thr Pro Tyr Glu Ile Trp Val Glu Ala 
                165                 170                 175     


Thr Asn Arg Leu Gly Ser Ala Arg Ser Asp Val Leu Thr Leu Asp Ile 
            180                 185                 190         


Leu Asp Val Val Thr Thr Asp Pro Pro Pro Asp Val His Val Ser Arg 
        195                 200                 205             


Val Gly Gly Leu Glu Asp Gln Leu Ser Val Arg Trp Val Ser Pro Pro 
    210                 215                 220                 


Ala Leu Lys Asp Phe Leu Phe Gln Ala Lys Tyr Gln Ile Arg Tyr Arg 
225                 230                 235                 240 


Val Glu Asp Ser Val Asp Trp Lys Val Val Asp Asp Val Ser Asn Gln 
                245                 250                 255     


Thr Ser Cys Arg Leu Ala Gly Leu Lys Pro Gly Thr Val Tyr Phe Val 
            260                 265                 270         


Gln Val Arg Cys Asn Pro Phe Gly Ile Tyr Gly Ser Lys Lys Ala Gly 
        275                 280                 285             


Ile Trp Ser Glu Trp Ser His Pro Thr Ala Ala Ser Thr Pro Arg Ser 
    290                 295                 300                 


Glu Arg Pro Gly Pro Gly Gly Gly Ala Cys Glu Pro Arg Gly Gly Glu 
305                 310                 315                 320 


Pro Ser Ser Gly Pro Val Arg Arg Glu Leu Lys Gln Phe Leu Gly Trp 
                325                 330                 335     


Leu Lys Lys His Ala Tyr Cys Ser Asn Leu Ser Phe Arg Leu Tyr Asp 
            340                 345                 350         


Gln Trp Arg Ala Trp Met Gln Lys Ser His Lys Thr Arg Asn Gln Asp 
        355                 360                 365             


Glu Gly Ile Leu Pro Ser Gly Arg Arg Gly Thr Ala Arg Gly Pro Ala 
    370                 375                 380                 


Arg 
385 


<210>  318
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  318

Gln Gly Gly Ala Ala Glu Gly Val Gln Ile Gln Ile Ile Tyr Phe Asn 
1               5                   10                  15      


Leu Glu Thr Val Gln Val Thr Trp Asn Ala Ser Lys Tyr Ser Arg Thr 
            20                  25                  30          


Asn Leu Thr Phe His Tyr Arg Phe Asn Gly Asp Glu Ala Tyr Asp Gln 
        35                  40                  45              


Cys Thr Asn Tyr Leu Leu Gln Glu Gly His Thr Ser Gly Cys Leu Leu 
    50                  55                  60                  


Asp Ala Glu Gln Arg Asp Asp Ile Leu Tyr Phe Ser Ile Arg Asn Gly 
65                  70                  75                  80  


Thr His Pro Val Phe Thr Ala Ser Arg Trp Met Val Tyr Tyr Leu Lys 
                85                  90                  95      


Pro Ser Ser Pro Lys His Val Arg Phe Ser Trp His Gln Asp Ala Val 
            100                 105                 110         


Thr Val Thr Cys Ser Asp Leu Ser Tyr Gly Asp Leu Leu Tyr Glu Val 
        115                 120                 125             


Gln Tyr Arg Ser Pro Phe Asp Thr Glu Trp Gln Ser Lys Gln Glu Asn 
    130                 135                 140                 


Thr Cys Asn Val Thr Ile Glu Gly Leu Asp Ala Glu Lys Cys Tyr Ser 
145                 150                 155                 160 


Phe Trp Val Arg Val Lys Ala Met Glu Asp Val Tyr Gly Pro Asp Thr 
                165                 170                 175     


Tyr Pro Ser Asp Trp Ser Glu Val Thr Cys Trp Gln Arg Gly Glu Ile 
            180                 185                 190         


Arg Asp Ala Cys Ala Glu Thr Pro Thr Pro Pro Lys Pro Lys Leu Ser 
        195                 200                 205             


Lys 
    


<210>  319
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  319

Asp Thr Asn Glu Cys Ile Gln Phe Pro Phe Val Cys Pro Arg Asp Lys 
1               5                   10                  15      


Pro Val Cys Val Asn Thr Tyr Gly Ser Tyr Arg Cys Arg Thr Asn Lys 
            20                  25                  30          


Lys Cys Ser Arg Gly Tyr Glu Pro Asn Glu Asp Gly Thr Ala Cys Val 
        35                  40                  45              


Gly Thr Leu Gly Gln Ser Pro Gly Pro Arg Pro Thr Thr Pro Thr Ala 
    50                  55                  60                  


Ala Ala Ala Thr Ala Ala Ala Ala Ala Ala Ala Gly Ala Ala Thr Ala 
65                  70                  75                  80  


Ala Pro Val Leu Val Asp Gly Asp Leu Asn Leu Gly Ser Val Val Lys 
                85                  90                  95      


Glu Ser Cys Glu Pro Ser Cys 
            100             


<210>  320
<211>  270
<212>  PRT
<213>  Homo Sapiens

<400>  320

Ser Leu Thr Asn His Thr Glu Thr Ile Thr Val Glu Glu Gly Gln Thr 
1               5                   10                  15      


Leu Thr Leu Lys Cys Val Thr Ser Leu Arg Lys Asn Ser Ser Leu Gln 
            20                  25                  30          


Trp Leu Thr Pro Ser Gly Phe Thr Ile Phe Leu Asn Glu Tyr Pro Val 
        35                  40                  45              


Leu Lys Asn Ser Lys Tyr Gln Leu Leu His His Ser Ala Asn Gln Leu 
    50                  55                  60                  


Ser Ile Thr Val Pro Asn Val Thr Leu Gln Asp Glu Gly Val Tyr Lys 
65                  70                  75                  80  


Cys Leu His Tyr Ser Asp Ser Val Ser Thr Lys Glu Val Lys Val Ile 
                85                  90                  95      


Val Leu Ala Thr Pro Phe Lys Pro Ile Leu Glu Ala Ser Val Ile Arg 
            100                 105                 110         


Lys Gln Asn Gly Glu Glu His Val Val Leu Met Cys Ser Thr Met Arg 
        115                 120                 125             


Ser Lys Pro Pro Pro Gln Ile Thr Trp Leu Leu Gly Asn Ser Met Glu 
    130                 135                 140                 


Val Ser Gly Gly Thr Leu His Glu Phe Glu Thr Asp Gly Lys Lys Cys 
145                 150                 155                 160 


Asn Thr Thr Ser Thr Leu Ile Ile His Thr Tyr Gly Lys Asn Ser Thr 
                165                 170                 175     


Val Asp Cys Ile Ile Arg His Arg Gly Leu Gln Gly Arg Lys Leu Val 
            180                 185                 190         


Ala Pro Phe Arg Phe Glu Asp Leu Val Thr Asp Glu Glu Thr Ala Ser 
        195                 200                 205             


Asp Ala Leu Glu Arg Asn Ser Leu Ser Ser Gln Asp Pro Gln Gln Pro 
    210                 215                 220                 


Thr Ser Thr Val Ser Val Thr Glu Asp Ser Ser Thr Ser Glu Ile Asp 
225                 230                 235                 240 


Lys Glu Glu Lys Glu Gln Thr Thr Gln Asp Pro Asp Leu Thr Thr Glu 
                245                 250                 255     


Ala Asn Pro Gln Tyr Leu Gly Leu Ala Arg Lys Lys Ser Gly 
            260                 265                 270 


<210>  321
<211>  498
<212>  PRT
<213>  Homo Sapiens

<400>  321

Ile Pro Val Ile Glu Pro Ser Val Pro Glu Leu Val Val Lys Pro Gly 
1               5                   10                  15      


Ala Thr Val Thr Leu Arg Cys Val Gly Asn Gly Ser Val Glu Trp Asp 
            20                  25                  30          


Gly Pro Pro Ser Pro His Trp Thr Leu Tyr Ser Asp Gly Ser Ser Ser 
        35                  40                  45              


Ile Leu Ser Thr Asn Asn Ala Thr Phe Gln Asn Thr Gly Thr Tyr Arg 
    50                  55                  60                  


Cys Thr Glu Pro Gly Asp Pro Leu Gly Gly Ser Ala Ala Ile His Leu 
65                  70                  75                  80  


Tyr Val Lys Asp Pro Ala Arg Pro Trp Asn Val Leu Ala Gln Glu Val 
                85                  90                  95      


Val Val Phe Glu Asp Gln Asp Ala Leu Leu Pro Cys Leu Leu Thr Asp 
            100                 105                 110         


Pro Val Leu Glu Ala Gly Val Ser Leu Val Arg Val Arg Gly Arg Pro 
        115                 120                 125             


Leu Met Arg His Thr Asn Tyr Ser Phe Ser Pro Trp His Gly Phe Thr 
    130                 135                 140                 


Ile His Arg Ala Lys Phe Ile Gln Ser Gln Asp Tyr Gln Cys Ser Ala 
145                 150                 155                 160 


Leu Met Gly Gly Arg Lys Val Met Ser Ile Ser Ile Arg Leu Lys Val 
                165                 170                 175     


Gln Lys Val Ile Pro Gly Pro Pro Ala Leu Thr Leu Val Pro Ala Glu 
            180                 185                 190         


Leu Val Arg Ile Arg Gly Glu Ala Ala Gln Ile Val Cys Ser Ala Ser 
        195                 200                 205             


Ser Val Asp Val Asn Phe Asp Val Phe Leu Gln His Asn Asn Thr Lys 
    210                 215                 220                 


Leu Ala Ile His Gln Gln Ser Asp Phe His Asn Asn Arg Tyr Gln Lys 
225                 230                 235                 240 


Val Leu Thr Leu Asn Leu Asp Gln Val Asp Phe Gln His Ala Gly Asn 
                245                 250                 255     


Tyr Ser Cys Val Ala Ser Asn Val Gln Gly Lys His Ser Thr Ser Met 
            260                 265                 270         


Phe Phe Arg Val Val Glu Ser Ala Tyr Leu Asn Leu Ser Ser Glu Gln 
        275                 280                 285             


Asn Leu Ile Gln Glu Val Thr Val Gly Glu Gly Leu Asn Leu Lys Val 
    290                 295                 300                 


Met Val Glu Ala Tyr Pro Gly Leu Gln Gly Phe Asn Trp Thr Tyr Leu 
305                 310                 315                 320 


Gly Pro Phe Ser Asp His Gln Pro Glu Pro Lys Leu Ala Asn Val Thr 
                325                 330                 335     


Thr Lys Asp Thr Tyr Arg His Thr Phe Thr Leu Ser Leu Pro Arg Leu 
            340                 345                 350         


Lys Pro Ser Glu Ala Gly Arg Tyr Ser Phe Leu Ala Arg Asn Pro Gly 
        355                 360                 365             


Gly Trp Arg Ala Leu Thr Phe Glu Leu Thr Leu Arg Tyr Pro Pro Glu 
    370                 375                 380                 


Val Ser Val Ile Trp Thr Phe Ile Asn Gly Ser Gly Thr Leu Leu Cys 
385                 390                 395                 400 


Ala Ala Ser Gly Tyr Pro Gln Pro Asn Val Thr Trp Leu Gln Cys Ser 
                405                 410                 415     


Gly His Thr Asp Arg Cys Asp Glu Ala Gln Val Leu Gln Val Trp Asp 
            420                 425                 430         


Asp Pro Tyr Pro Glu Val Leu Ser Gln Glu Pro Phe His Lys Val Thr 
        435                 440                 445             


Val Gln Ser Leu Leu Thr Val Glu Thr Leu Glu His Asn Gln Thr Tyr 
    450                 455                 460                 


Glu Cys Arg Ala His Asn Ser Val Gly Ser Gly Ser Trp Ala Phe Ile 
465                 470                 475                 480 


Pro Ile Ser Ala Gly Ala His Thr His Pro Pro Asp Glu Phe Leu Phe 
                485                 490                 495     


Thr Pro 
        


<210>  322
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  322

Ala Pro Ala Arg Ser Pro Ser Pro Ser Thr Gln Pro Trp Glu His Val 
1               5                   10                  15      


Asn Ala Ile Gln Glu Ala Arg Arg Leu Leu Asn Leu Ser Arg Asp Thr 
            20                  25                  30          


Ala Ala Glu Met Asn Glu Thr Val Glu Val Ile Ser Glu Met Phe Asp 
        35                  40                  45              


Leu Gln Glu Pro Thr Cys Leu Gln Thr Arg Leu Glu Leu Tyr Lys Gln 
    50                  55                  60                  


Gly Leu Arg Gly Ser Leu Thr Lys Leu Lys Gly Pro Leu Thr Met Met 
65                  70                  75                  80  


Ala Ser His Tyr Lys Gln His Cys Pro Pro Thr Pro Glu Thr Ser Cys 
                85                  90                  95      


Ala Thr Gln Ile Ile Thr Phe Glu Ser Phe Lys Glu Asn Leu Lys Asp 
            100                 105                 110         


Phe Leu Leu Val Ile Pro Phe Asp Cys Trp Glu Pro Val Gln Glu 
        115                 120                 125         


<210>  323
<211>  298
<212>  PRT
<213>  Homo Sapiens

<400>  323

Glu Lys Ser Asp Leu Arg Thr Val Ala Pro Ala Ser Ser Leu Asn Val 
1               5                   10                  15      


Arg Phe Asp Ser Arg Thr Met Asn Leu Ser Trp Asp Cys Gln Glu Asn 
            20                  25                  30          


Thr Thr Phe Ser Lys Cys Phe Leu Thr Asp Lys Lys Asn Arg Val Val 
        35                  40                  45              


Glu Pro Arg Leu Ser Asn Asn Glu Cys Ser Cys Thr Phe Arg Glu Ile 
    50                  55                  60                  


Cys Leu His Glu Gly Val Thr Phe Glu Val His Val Asn Thr Ser Gln 
65                  70                  75                  80  


Arg Gly Phe Gln Gln Lys Leu Leu Tyr Pro Asn Ser Gly Arg Glu Gly 
                85                  90                  95      


Thr Ala Ala Gln Asn Phe Ser Cys Phe Ile Tyr Asn Ala Asp Leu Met 
            100                 105                 110         


Asn Cys Thr Trp Ala Arg Gly Pro Thr Ala Pro Arg Asp Val Gln Tyr 
        115                 120                 125             


Phe Leu Tyr Ile Arg Asn Ser Lys Arg Arg Arg Glu Ile Arg Cys Pro 
    130                 135                 140                 


Tyr Tyr Ile Gln Asp Ser Gly Thr His Val Gly Cys His Leu Asp Asn 
145                 150                 155                 160 


Leu Ser Gly Leu Thr Ser Arg Asn Tyr Phe Leu Val Asn Gly Thr Ser 
                165                 170                 175     


Arg Glu Ile Gly Ile Gln Phe Phe Asp Ser Leu Leu Asp Thr Lys Lys 
            180                 185                 190         


Ile Glu Arg Phe Asn Pro Pro Ser Asn Val Thr Val Arg Cys Asn Thr 
        195                 200                 205             


Thr His Cys Leu Val Arg Trp Lys Gln Pro Arg Thr Tyr Gln Lys Leu 
    210                 215                 220                 


Ser Tyr Leu Asp Phe Gln Tyr Gln Leu Asp Val His Arg Lys Asn Thr 
225                 230                 235                 240 


Gln Pro Gly Thr Glu Asn Leu Leu Ile Asn Val Ser Gly Asp Leu Glu 
                245                 250                 255     


Asn Arg Tyr Asn Phe Pro Ser Ser Glu Pro Arg Ala Lys His Ser Val 
            260                 265                 270         


Lys Ile Arg Ala Ala Asp Val Arg Ile Leu Asn Trp Ser Ser Trp Ser 
        275                 280                 285             


Glu Ala Ile Glu Phe Gly Ser Asp Asp Gly 
    290                 295             


<210>  324
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  324

Glu Glu Thr Ile Pro Leu Gln Thr Leu Arg Cys Tyr Asn Asp Tyr Thr 
1               5                   10                  15      


Ser His Ile Thr Cys Arg Trp Ala Asp Thr Gln Asp Ala Gln Arg Leu 
            20                  25                  30          


Val Asn Val Thr Leu Ile Arg Arg Val Asn Glu Asp Leu Leu Glu Pro 
        35                  40                  45              


Val Ser Cys Asp Leu Ser Asp Asp Met Pro Trp Ser Ala Cys Pro His 
    50                  55                  60                  


Pro Arg Cys Val Pro Arg Arg Cys Val Ile Pro Cys Gln Ser Phe Val 
65                  70                  75                  80  


Val Thr Asp Val Asp Tyr Phe Ser Phe Gln Pro Asp Arg Pro Leu Gly 
                85                  90                  95      


Thr Arg Leu Thr Val Thr Leu Thr Gln His Val Gln Pro Pro Glu Pro 
            100                 105                 110         


Arg Asp Leu Gln Ile Ser Thr Asp Gln Asp His Phe Leu Leu Thr Trp 
        115                 120                 125             


Ser Val Ala Leu Gly Ser Pro Gln Ser His Trp Leu Ser Pro Gly Asp 
    130                 135                 140                 


Leu Glu Phe Glu Val Val Tyr Lys Arg Leu Gln Asp Ser Trp Glu Asp 
145                 150                 155                 160 


Ala Ala Ile Leu Leu Ser Asn Thr Ser Gln Ala Thr Leu Gly Pro Glu 
                165                 170                 175     


His Leu Met Pro Ser Ser Thr Tyr Val Ala Arg Val Arg Thr Arg Leu 
            180                 185                 190         


Ala Pro Gly Ser Arg Leu Ser Gly Arg Pro Ser Lys Trp Ser Pro Glu 
        195                 200                 205             


Val Cys Trp Asp Ser Gln Pro Gly Asp Glu Ala Gln Pro Gln Asn Leu 
    210                 215                 220                 


Glu Cys Phe Phe Asp Gly Ala Ala Val Leu Ser Cys Ser Trp Glu Val 
225                 230                 235                 240 


Arg Lys Glu Val Ala Ser Ser Val Ser Phe Gly Leu Phe Tyr Lys Pro 
                245                 250                 255     


Ser Pro Asp Ala Gly Ser Ala Val Leu Leu Arg Glu Glu Glu Cys Ser 
            260                 265                 270         


Pro Val Leu Arg Glu Gly Leu Gly Ser Leu His Thr Arg His His Cys 
        275                 280                 285             


Gln Ile Pro Val Pro Asp Pro Ala Thr His Gly Gln Tyr Ile Val Ser 
    290                 295                 300                 


Val Gln Pro Arg Arg Ala Glu Lys His Ile Lys Ser Ser Val Asn Ile 
305                 310                 315                 320 


Gln Met Ala Pro Pro Ser Leu Asn Val Thr Lys Asp Gly Asp Ser Tyr 
                325                 330                 335     


Ser Leu Arg Trp Glu Thr Met Lys Met Arg Tyr Glu His Ile Asp His 
            340                 345                 350         


Thr Phe Glu Ile Gln Tyr Arg Lys Asp Thr Ala Thr Trp Lys Asp Ser 
        355                 360                 365             


Lys Thr Glu Thr Leu Gln Asn Ala His Ser Met Ala Leu Pro Ala Leu 
    370                 375                 380                 


Glu Pro Ser Thr Arg Tyr Trp Ala Arg Val Arg Val Arg Thr Ser Arg 
385                 390                 395                 400 


Thr Gly Tyr Asn Gly Ile Trp Ser Glu Trp Ser Glu Ala Arg Ser Trp 
                405                 410                 415     


Asp Thr Glu Ser Val Leu Pro Met Trp 
            420                 425 


<210>  325
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  325

Ala Thr Pro Leu Gly Pro Ala Ser Ser Leu Pro Gln Ser Phe Leu Leu 
1               5                   10                  15      


Lys Cys Leu Glu Gln Val Arg Lys Ile Gln Gly Asp Gly Ala Ala Leu 
            20                  25                  30          


Gln Glu Lys Leu Cys Ala Thr Tyr Lys Leu Cys His Pro Glu Glu Leu 
        35                  40                  45              


Val Leu Leu Gly His Ser Leu Gly Ile Pro Trp Ala Pro Leu Ser Ser 
    50                  55                  60                  


Cys Pro Ser Gln Ala Leu Gln Leu Ala Gly Cys Leu Ser Gln Leu His 
65                  70                  75                  80  


Ser Gly Leu Phe Leu Tyr Gln Gly Leu Leu Gln Ala Leu Glu Gly Ile 
                85                  90                  95      


Ser Pro Glu Leu Gly Pro Thr Leu Asp Thr Leu Gln Leu Asp Val Ala 
            100                 105                 110         


Asp Phe Ala Thr Thr Ile Trp Gln Gln Met Glu Glu Leu Gly Met Ala 
        115                 120                 125             


Pro Ala Leu Gln Pro Thr Gln Gly Ala Met Pro Ala Phe Ala Ser Ala 
    130                 135                 140                 


Phe Gln Arg Arg Ala Gly Gly Val Leu Val Ala Ser His Leu Gln Ser 
145                 150                 155                 160 


Phe Leu Glu Val Ser Tyr Arg Val Leu Arg His Leu Ala Gln Pro 
                165                 170                 175 


<210>  326
<211>  603
<212>  PRT
<213>  Homo Sapiens

<400>  326

Glu Cys Gly His Ile Ser Val Ser Ala Pro Ile Val His Leu Gly Asp 
1               5                   10                  15      


Pro Ile Thr Ala Ser Cys Ile Ile Lys Gln Asn Cys Ser His Leu Asp 
            20                  25                  30          


Pro Glu Pro Gln Ile Leu Trp Arg Leu Gly Ala Glu Leu Gln Pro Gly 
        35                  40                  45              


Gly Arg Gln Gln Arg Leu Ser Asp Gly Thr Gln Glu Ser Ile Ile Thr 
    50                  55                  60                  


Leu Pro His Leu Asn His Thr Gln Ala Phe Leu Ser Cys Cys Leu Asn 
65                  70                  75                  80  


Trp Gly Asn Ser Leu Gln Ile Leu Asp Gln Val Glu Leu Arg Ala Gly 
                85                  90                  95      


Tyr Pro Pro Ala Ile Pro His Asn Leu Ser Cys Leu Met Asn Leu Thr 
            100                 105                 110         


Thr Ser Ser Leu Ile Cys Gln Trp Glu Pro Gly Pro Glu Thr His Leu 
        115                 120                 125             


Pro Thr Ser Phe Thr Leu Lys Ser Phe Lys Ser Arg Gly Asn Cys Gln 
    130                 135                 140                 


Thr Gln Gly Asp Ser Ile Leu Asp Cys Val Pro Lys Asp Gly Gln Ser 
145                 150                 155                 160 


His Cys Cys Ile Pro Arg Lys His Leu Leu Leu Tyr Gln Asn Met Gly 
                165                 170                 175     


Ile Trp Val Gln Ala Glu Asn Ala Leu Gly Thr Ser Met Ser Pro Gln 
            180                 185                 190         


Leu Cys Leu Asp Pro Met Asp Val Val Lys Leu Glu Pro Pro Met Leu 
        195                 200                 205             


Arg Thr Met Asp Pro Ser Pro Glu Ala Ala Pro Pro Gln Ala Gly Cys 
    210                 215                 220                 


Leu Gln Leu Cys Trp Glu Pro Trp Gln Pro Gly Leu His Ile Asn Gln 
225                 230                 235                 240 


Lys Cys Glu Leu Arg His Lys Pro Gln Arg Gly Glu Ala Ser Trp Ala 
                245                 250                 255     


Leu Val Gly Pro Leu Pro Leu Glu Ala Leu Gln Tyr Glu Leu Cys Gly 
            260                 265                 270         


Leu Leu Pro Ala Thr Ala Tyr Thr Leu Gln Ile Arg Cys Ile Arg Trp 
        275                 280                 285             


Pro Leu Pro Gly His Trp Ser Asp Trp Ser Pro Ser Leu Glu Leu Arg 
    290                 295                 300                 


Thr Thr Glu Arg Ala Pro Thr Val Arg Leu Asp Thr Trp Trp Arg Gln 
305                 310                 315                 320 


Arg Gln Leu Asp Pro Arg Thr Val Gln Leu Phe Trp Lys Pro Val Pro 
                325                 330                 335     


Leu Glu Glu Asp Ser Gly Arg Ile Gln Gly Tyr Val Val Ser Trp Arg 
            340                 345                 350         


Pro Ser Gly Gln Ala Gly Ala Ile Leu Pro Leu Cys Asn Thr Thr Glu 
        355                 360                 365             


Leu Ser Cys Thr Phe His Leu Pro Ser Glu Ala Gln Glu Val Ala Leu 
    370                 375                 380                 


Val Ala Tyr Asn Ser Ala Gly Thr Ser Arg Pro Thr Pro Val Val Phe 
385                 390                 395                 400 


Ser Glu Ser Arg Gly Pro Ala Leu Thr Arg Leu His Ala Met Ala Arg 
                405                 410                 415     


Asp Pro His Ser Leu Trp Val Gly Trp Glu Pro Pro Asn Pro Trp Pro 
            420                 425                 430         


Gln Gly Tyr Val Ile Glu Trp Gly Leu Gly Pro Pro Ser Ala Ser Asn 
        435                 440                 445             


Ser Asn Lys Thr Trp Arg Met Glu Gln Asn Gly Arg Ala Thr Gly Phe 
    450                 455                 460                 


Leu Leu Lys Glu Asn Ile Arg Pro Phe Gln Leu Tyr Glu Ile Ile Val 
465                 470                 475                 480 


Thr Pro Leu Tyr Gln Asp Thr Met Gly Pro Ser Gln His Val Tyr Ala 
                485                 490                 495     


Tyr Ser Gln Glu Met Ala Pro Ser His Ala Pro Glu Leu His Leu Lys 
            500                 505                 510         


His Ile Gly Lys Thr Trp Ala Gln Leu Glu Trp Val Pro Glu Pro Pro 
        515                 520                 525             


Glu Leu Gly Lys Ser Pro Leu Thr His Tyr Thr Ile Phe Trp Thr Asn 
    530                 535                 540                 


Ala Gln Asn Gln Ser Phe Ser Ala Ile Leu Asn Ala Ser Ser Arg Gly 
545                 550                 555                 560 


Phe Val Leu His Gly Leu Glu Pro Ala Ser Leu Tyr His Ile His Leu 
                565                 570                 575     


Met Ala Ala Ser Gln Ala Gly Ala Thr Asn Ser Thr Val Leu Thr Leu 
            580                 585                 590         


Met Thr Leu Thr Pro Glu Gly Ser Glu Leu His 
        595                 600             


<210>  327
<211>  393
<212>  PRT
<213>  Homo Sapiens

<400>  327

Val Pro Ala Arg Glu Ala Gly Ser Ala Val Glu Ala Glu Glu Leu Val 
1               5                   10                  15      


Lys Gly Ser Pro Ala Trp Glu Pro Pro Ala Asn Asp Thr Arg Glu Glu 
            20                  25                  30          


Ala Gly Pro Pro Ala Ala Gly Glu Asp Glu Ala Ser Trp Thr Ala Pro 
        35                  40                  45              


Gly Gly Glu Leu Ala Gly Pro Glu Glu Val Leu Gln Glu Ser Ala Ala 
    50                  55                  60                  


Val Thr Gly Thr Ala Trp Leu Glu Ala Asp Ser Pro Gly Leu Gly Gly 
65                  70                  75                  80  


Val Thr Ala Glu Ala Gly Ser Gly Asp Ala Gln Ala Leu Pro Ala Thr 
                85                  90                  95      


Leu Gln Ala Pro His Glu Val Leu Gly Gln Ser Ile Met Pro Pro Ala 
            100                 105                 110         


Ile Pro Glu Ala Thr Glu Ala Ser Gly Pro Pro Ser Pro Thr Pro Gly 
        115                 120                 125             


Asp Lys Leu Ser Pro Ala Ser Glu Leu Pro Lys Glu Ser Pro Leu Glu 
    130                 135                 140                 


Val Trp Leu Asn Leu Gly Gly Ser Thr Pro Asp Pro Gln Gly Pro Glu 
145                 150                 155                 160 


Leu Thr Tyr Pro Phe Gln Gly Thr Leu Glu Pro Gln Pro Ala Ser Asp 
                165                 170                 175     


Ile Ile Asp Ile Asp Tyr Phe Glu Gly Leu Asp Gly Glu Gly Arg Gly 
            180                 185                 190         


Ala Asp Leu Gly Ser Phe Pro Gly Ser Pro Gly Thr Ser Glu Asn His 
        195                 200                 205             


Pro Asp Thr Glu Gly Glu Thr Pro Ser Trp Ser Leu Leu Asp Leu Tyr 
    210                 215                 220                 


Asp Asp Phe Thr Pro Phe Asp Glu Ser Asp Phe Tyr Pro Thr Thr Ser 
225                 230                 235                 240 


Phe Tyr Asp Asp Leu Asp Glu Glu Glu Glu Glu Glu Glu Asp Asp Lys 
                245                 250                 255     


Asp Ala Val Gly Gly Gly Asp Leu Glu Asp Glu Asn Glu Leu Leu Val 
            260                 265                 270         


Pro Thr Gly Lys Pro Gly Leu Gly Pro Gly Thr Gly Gln Pro Thr Ser 
        275                 280                 285             


Arg Trp His Ala Val Pro Pro Gln His Thr Leu Gly Ser Val Pro Gly 
    290                 295                 300                 


Ser Ser Ile Ala Leu Arg Pro Arg Pro Gly Glu Pro Gly Arg Asp Leu 
305                 310                 315                 320 


Ala Ser Ser Glu Asn Gly Thr Glu Cys Arg Ser Gly Phe Val Arg His 
                325                 330                 335     


Asn Gly Ser Cys Arg Ser Val Cys Asp Leu Phe Pro Ser Tyr Cys His 
            340                 345                 350         


Asn Gly Gly Gln Cys Tyr Leu Val Glu Asn Ile Gly Ala Phe Cys Arg 
        355                 360                 365             


Cys Asn Thr Gln Asp Tyr Ile Trp His Lys Gly Met Arg Cys Glu Ser 
    370                 375                 380                 


Ile Ile Thr Asp Phe Gln Val Met Cys 
385                 390             


<210>  328
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  328

Lys Ala Met His Val Ala Gln Pro Ala Val Val Leu Ala Ser Ser Arg 
1               5                   10                  15      


Gly Ile Ala Ser Phe Val Cys Glu Tyr Ala Ser Pro Gly Lys Ala Thr 
            20                  25                  30          


Glu Val Arg Val Thr Val Leu Arg Gln Ala Asp Ser Gln Val Thr Glu 
        35                  40                  45              


Val Cys Ala Ala Thr Tyr Met Met Gly Asn Glu Leu Thr Phe Leu Asp 
    50                  55                  60                  


Asp Ser Ile Cys Thr Gly Thr Ser Ser Gly Asn Gln Val Asn Leu Thr 
65                  70                  75                  80  


Ile Gln Gly Leu Arg Ala Met Asp Thr Gly Leu Tyr Ile Cys Lys Val 
                85                  90                  95      


Glu Leu Met Tyr Pro Pro Pro Tyr Tyr Leu Gly Ile Gly Asn Gly Thr 
            100                 105                 110         


Gln Ile Tyr Val Ile Asp Pro Glu Pro Cys Pro Asp Ser Asp 
        115                 120                 125     


<210>  329
<211>  315
<212>  PRT
<213>  Homo Sapiens

<400>  329

Gln His His Gly Val Thr Lys Cys Asn Ile Thr Cys Ser Lys Met Thr 
1               5                   10                  15      


Ser Lys Ile Pro Val Ala Leu Leu Ile His Tyr Gln Gln Asn Gln Ala 
            20                  25                  30          


Ser Cys Gly Lys Arg Ala Ile Ile Leu Glu Thr Arg Gln His Arg Leu 
        35                  40                  45              


Phe Cys Ala Asp Pro Lys Glu Gln Trp Val Lys Asp Ala Met Gln His 
    50                  55                  60                  


Leu Asp Arg Gln Ala Ala Ala Leu Thr Arg Asn Gly Gly Thr Phe Glu 
65                  70                  75                  80  


Lys Gln Ile Gly Glu Val Lys Pro Arg Thr Thr Pro Ala Ala Gly Gly 
                85                  90                  95      


Met Asp Glu Ser Val Val Leu Glu Pro Glu Ala Thr Gly Glu Ser Ser 
            100                 105                 110         


Ser Leu Glu Pro Thr Pro Ser Ser Gln Glu Ala Gln Arg Ala Leu Gly 
        115                 120                 125             


Thr Ser Pro Glu Leu Pro Thr Gly Val Thr Gly Ser Ser Gly Thr Arg 
    130                 135                 140                 


Leu Pro Pro Thr Pro Lys Ala Gln Asp Gly Gly Pro Val Gly Thr Glu 
145                 150                 155                 160 


Leu Phe Arg Val Pro Pro Val Ser Thr Ala Ala Thr Trp Gln Ser Ser 
                165                 170                 175     


Ala Pro His Gln Pro Gly Pro Ser Leu Trp Ala Glu Ala Lys Thr Ser 
            180                 185                 190         


Glu Ala Pro Ser Thr Gln Asp Pro Ser Thr Gln Ala Ser Thr Ala Ser 
        195                 200                 205             


Ser Pro Ala Pro Glu Glu Asn Ala Pro Ser Glu Gly Gln Arg Val Trp 
    210                 215                 220                 


Gly Gln Gly Gln Ser Pro Arg Pro Glu Asn Ser Leu Glu Arg Glu Glu 
225                 230                 235                 240 


Met Gly Pro Val Pro Ala His Thr Asp Ala Phe Gln Asp Trp Gly Pro 
                245                 250                 255     


Gly Ser Met Ala His Val Ser Val Val Pro Val Ser Ser Glu Gly Thr 
            260                 265                 270         


Pro Ser Arg Glu Pro Val Ala Ser Gly Ser Trp Thr Pro Lys Ala Glu 
        275                 280                 285             


Glu Pro Ile His Ala Thr Met Asp Pro Gln Arg Leu Gly Val Leu Ile 
    290                 295                 300                 


Thr Pro Val Pro Asp Ala Gln Ala Ala Thr Arg 
305                 310                 315 


<210>  330
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  330

Leu Ser Ile Thr Thr Pro Glu Glu Met Ile Glu Lys Ala Lys Gly Glu 
1               5                   10                  15      


Thr Ala Tyr Leu Pro Cys Lys Phe Thr Leu Ser Pro Glu Asp Gln Gly 
            20                  25                  30          


Pro Leu Asp Ile Glu Trp Leu Ile Ser Pro Ala Asp Asn Gln Lys Val 
        35                  40                  45              


Asp Gln Val Ile Ile Leu Tyr Ser Gly Asp Lys Ile Tyr Asp Asp Tyr 
    50                  55                  60                  


Tyr Pro Asp Leu Lys Gly Arg Val His Phe Thr Ser Asn Asp Leu Lys 
65                  70                  75                  80  


Ser Gly Asp Ala Ser Ile Asn Val Thr Asn Leu Gln Leu Ser Asp Ile 
                85                  90                  95      


Gly Thr Tyr Gln Cys Lys Val Lys Lys Ala Pro Gly Val Ala Asn Lys 
            100                 105                 110         


Lys Ile His Leu Val Val Leu Val Lys Pro Ser Gly Ala Arg Cys Tyr 
        115                 120                 125             


Val Asp Gly Ser Glu Glu Ile Gly Ser Asp Phe Lys Ile Lys Cys Glu 
    130                 135                 140                 


Pro Lys Glu Gly Ser Leu Pro Leu Gln Tyr Glu Trp Gln Lys Leu Ser 
145                 150                 155                 160 


Asp Ser Gln Lys Met Pro Thr Ser Trp Leu Ala Glu Met Thr Ser Ser 
                165                 170                 175     


Val Ile Ser Val Lys Asn Ala Ser Ser Glu Tyr Ser Gly Thr Tyr Ser 
            180                 185                 190         


Cys Thr Val Arg Asn Arg Val Gly Ser Asp Gln Cys Leu Leu Arg Leu 
        195                 200                 205             


Asn Val Val Pro Pro Ser Asn Lys Ala Gly 
    210                 215             


<210>  331
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  331

Ala Ser Val Ala Thr Glu Leu Arg Cys Gln Cys Leu Gln Thr Leu Gln 
1               5                   10                  15      


Gly Ile His Pro Lys Asn Ile Gln Ser Val Asn Val Lys Ser Pro Gly 
            20                  25                  30          


Pro His Cys Ala Gln Thr Glu Val Ile Ala Thr Leu Lys Asn Gly Arg 
        35                  40                  45              


Lys Ala Cys Leu Asn Pro Ala Ser Pro Ile Val Lys Lys Ile Ile Glu 
    50                  55                  60                  


Lys Met Leu Asn Ser Asp Lys Ser Asn 
65                  70              


<210>  332
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  332

Val Pro Leu Ser Arg Thr Val Arg Cys Thr Cys Ile Ser Ile Ser Asn 
1               5                   10                  15      


Gln Pro Val Asn Pro Arg Ser Leu Glu Lys Leu Glu Ile Ile Pro Ala 
            20                  25                  30          


Ser Gln Phe Cys Pro Arg Val Glu Ile Ile Ala Thr Met Lys Lys Lys 
        35                  40                  45              


Gly Glu Lys Arg Cys Leu Asn Pro Glu Ser Lys Ala Ile Lys Asn Leu 
    50                  55                  60                  


Leu Lys Ala Val Ser Lys Glu Arg Ser Lys Arg Ser Pro 
65                  70                  75          


<210>  333
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  333

Phe Pro Met Phe Lys Arg Gly Arg Cys Leu Cys Ile Gly Pro Gly Val 
1               5                   10                  15      


Lys Ala Val Lys Val Ala Asp Ile Glu Lys Ala Ser Ile Met Tyr Pro 
            20                  25                  30          


Ser Asn Asn Cys Asp Lys Ile Glu Val Ile Ile Thr Leu Lys Glu Asn 
        35                  40                  45              


Lys Gly Gln Arg Cys Leu Asn Pro Lys Ser Lys Gln Ala Arg Leu Ile 
    50                  55                  60                  


Ile Lys Lys Val Glu Arg Lys Asn Phe 
65                  70              


<210>  334
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  334

Lys Pro Val Ser Leu Ser Tyr Arg Cys Pro Cys Arg Phe Phe Glu Ser 
1               5                   10                  15      


His Val Ala Arg Ala Asn Val Lys His Leu Lys Ile Leu Asn Thr Pro 
            20                  25                  30          


Asn Cys Ala Leu Gln Ile Val Ala Arg Leu Lys Asn Asn Asn Arg Gln 
        35                  40                  45              


Val Cys Ile Asp Pro Lys Leu Lys Trp Ile Gln Glu Tyr Leu Glu Lys 
    50                  55                  60                  


Ala Leu Asn Lys 
65              


<210>  335
<211>  87
<212>  PRT
<213>  Homo Sapiens

<400>  335

Val Leu Glu Val Tyr Tyr Thr Ser Leu Arg Cys Arg Cys Val Gln Glu 
1               5                   10                  15      


Ser Ser Val Phe Ile Pro Arg Arg Phe Ile Asp Arg Ile Gln Ile Leu 
            20                  25                  30          


Pro Arg Gly Asn Gly Cys Pro Arg Lys Glu Ile Ile Val Trp Lys Lys 
        35                  40                  45              


Asn Lys Ser Ile Val Cys Val Asp Pro Gln Ala Glu Trp Ile Gln Arg 
    50                  55                  60                  


Met Met Glu Val Leu Arg Lys Arg Ser Ser Ser Thr Leu Pro Val Pro 
65                  70                  75                  80  


Val Phe Lys Arg Lys Ile Pro 
                85          


<210>  336
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  336

Ser Lys Cys Lys Cys Ser Arg Lys Gly Pro Lys Ile Arg Tyr Ser Asp 
1               5                   10                  15      


Val Lys Lys Leu Glu Met Lys Pro Lys Tyr Pro His Cys Glu Glu Lys 
            20                  25                  30          


Met Val Ile Ile Thr Thr Lys Ser Val Ser Arg Tyr Arg Gly Gln Glu 
        35                  40                  45              


His Cys Leu His Pro Lys Leu Gln Ser Thr Lys Arg Phe Ile Lys Trp 
    50                  55                  60                  


Tyr Asn Ala Trp Asn Glu Lys Arg Arg Val Tyr Glu Glu 
65                  70                  75          


<210>  337
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  337

Asn Glu Gly Ser Val Thr Gly Ser Cys Tyr Cys Gly Lys Arg Ile Ser 
1               5                   10                  15      


Ser Asp Ser Pro Pro Ser Val Gln Phe Met Asn Arg Leu Arg Lys His 
            20                  25                  30          


Leu Arg Ala Tyr His Arg Cys Leu Tyr Tyr Thr Arg Phe Gln Leu Leu 
        35                  40                  45              


Ser Trp Ser Val Cys Gly Gly Asn Lys Asp Pro Trp Val Gln Glu Leu 
    50                  55                  60                  


Met Ser Cys Leu Asp Leu Lys Glu Cys Gly His Ala Tyr Ser Gly Ile 
65                  70                  75                  80  


Val Ala His Gln Lys His Leu Leu Pro Thr Ser Pro Pro Ile Ser Gln 
                85                  90                  95      


Ala Ser Glu Gly Ala Ser Ser Asp Ile His Thr Pro Ala Gln Met Leu 
            100                 105                 110         


Leu Ser Thr Leu Gln Ser Thr Gln Arg Pro Thr Leu Pro Val Gly Ser 
        115                 120                 125             


Leu Ser Ser Asp Lys Glu Leu Thr Arg Pro Asn Glu Thr Thr Ile His 
    130                 135                 140                 


Thr Ala Gly His Ser Leu Ala Ala Gly Pro Glu Ala Gly Glu Asn Gln 
145                 150                 155                 160 


Lys Gln Pro Glu Lys Asn Ala Gly Pro Thr Ala Arg Thr Ser Ala Thr 
                165                 170                 175     


<210>  338
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  338

Phe Met Thr Val Ser Gly Leu Pro Lys Lys Gln Cys Pro Cys Asp His 
1               5                   10                  15      


Phe Lys Gly Asn Val Lys Lys Thr Arg His Gln Arg His His Arg Lys 
            20                  25                  30          


Pro Asn Lys His Ser Arg Ala Cys Gln Gln Phe Leu Lys Gln Cys Gln 
        35                  40                  45              


Leu Arg Ser Phe Ala Leu Pro Leu 
    50                  55      


<210>  339
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  339

Thr Glu Leu Arg Cys Gln Cys Leu Gln Thr Leu Gln Gly Ile His Leu 
1               5                   10                  15      


Lys Asn Ile Gln Ser Val Lys Val Lys Ser Pro Gly Pro His Cys Ala 
            20                  25                  30          


Gln Thr Glu Val Ile Ala Thr Leu Lys Asn Gly Gln Lys Ala Cys Leu 
        35                  40                  45              


Asn Pro Ala Ser Pro Met Val Lys Lys Ile Ile Glu Lys Met Leu Lys 
    50                  55                  60                  


Asn Gly Lys Ser Asn 
65                  


<210>  340
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  340

Ala Ser Val Val Thr Glu Leu Arg Cys Gln Cys Leu Gln Thr Leu Gln 
1               5                   10                  15      


Gly Ile His Leu Lys Asn Ile Gln Ser Val Asn Val Arg Ser Pro Gly 
            20                  25                  30          


Pro His Cys Ala Gln Thr Glu Val Ile Ala Thr Leu Lys Asn Gly Lys 
        35                  40                  45              


Lys Ala Cys Leu Asn Pro Ala Ser Pro Met Val Gln Lys Ile Ile Glu 
    50                  55                  60                  


Lys Ile Leu Asn Lys Gly Ser Thr Asn 
65                  70              


<210>  341
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  341

Leu Arg Glu Leu Arg Cys Val Cys Leu Gln Thr Thr Gln Gly Val His 
1               5                   10                  15      


Pro Lys Met Ile Ser Asn Leu Gln Val Phe Ala Ile Gly Pro Gln Cys 
            20                  25                  30          


Ser Lys Val Glu Val Val Ala Ser Leu Lys Asn Gly Lys Glu Ile Cys 
        35                  40                  45              


Leu Asp Pro Glu Ala Pro Phe Leu Lys Lys Val Ile Gln Lys Ile Leu 
    50                  55                  60                  


Asp Gly Gly Asn Lys Glu Asn 
65                  70      


<210>  342
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  342

Gly Pro Val Ser Ala Val Leu Thr Glu Leu Arg Cys Thr Cys Leu Arg 
1               5                   10                  15      


Val Thr Leu Arg Val Asn Pro Lys Thr Ile Gly Lys Leu Gln Val Phe 
            20                  25                  30          


Pro Ala Gly Pro Gln Cys Ser Lys Val Glu Val Val Ala Ser Leu Lys 
        35                  40                  45              


Asn Gly Lys Gln Val Cys Leu Asp Pro Glu Ala Pro Phe Leu Lys Lys 
    50                  55                  60                  


Val Ile Gln Lys Ile Leu Asp Ser Gly Asn Lys Lys Asn 
65                  70                  75          


<210>  343
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  343

Thr Pro Val Val Arg Lys Gly Arg Cys Ser Cys Ile Ser Thr Asn Gln 
1               5                   10                  15      


Gly Thr Ile His Leu Gln Ser Leu Lys Asp Leu Lys Gln Phe Ala Pro 
            20                  25                  30          


Ser Pro Ser Cys Glu Lys Ile Glu Ile Ile Ala Thr Leu Lys Asn Gly 
        35                  40                  45              


Val Gln Thr Cys Leu Asn Pro Asp Ser Ala Asp Val Lys Glu Leu Ile 
    50                  55                  60                  


Lys Lys Trp Glu Lys Gln Val Ser Gln Lys Lys Lys Gln Lys Asn Gly 
65                  70                  75                  80  


Lys Lys His Gln Lys Lys Lys Val Leu Lys Val Arg Lys Ser Gln Arg 
                85                  90                  95      


Ser Arg Gln Lys Lys Thr Thr 
            100             


<210>  344
<211>  624
<212>  PRT
<213>  Homo Sapiens

<400>  344

His Trp Pro Ser Glu Pro Ser Glu Ala Val Arg Asp Trp Glu Asn Gln 
1               5                   10                  15      


Leu Glu Ala Ser Met His Ser Val Leu Ser Asp Leu His Glu Ala Val 
            20                  25                  30          


Pro Thr Val Val Gly Ile Pro Asp Gly Thr Ala Val Val Gly Arg Ser 
        35                  40                  45              


Phe Arg Val Thr Ile Pro Thr Asp Leu Ile Ala Ser Ser Gly Asp Ile 
    50                  55                  60                  


Ile Lys Val Ser Ala Ala Gly Lys Glu Ala Leu Pro Ser Trp Leu His 
65                  70                  75                  80  


Trp Asp Ser Gln Ser His Thr Leu Glu Gly Leu Pro Leu Asp Thr Asp 
                85                  90                  95      


Lys Gly Val His Tyr Ile Ser Val Ser Ala Thr Arg Leu Gly Ala Asn 
            100                 105                 110         


Gly Ser His Ile Pro Gln Thr Ser Ser Val Phe Ser Ile Glu Val Tyr 
        115                 120                 125             


Pro Glu Asp His Ser Glu Leu Gln Ser Val Arg Thr Ala Ser Pro Asp 
    130                 135                 140                 


Pro Gly Glu Val Val Ser Ser Ala Cys Ala Ala Asp Glu Pro Val Thr 
145                 150                 155                 160 


Val Leu Thr Val Ile Leu Asp Ala Asp Leu Thr Lys Met Thr Pro Lys 
                165                 170                 175     


Gln Arg Ile Asp Leu Leu His Arg Met Arg Ser Phe Ser Glu Val Glu 
            180                 185                 190         


Leu His Asn Met Lys Leu Val Pro Val Val Asn Asn Arg Leu Phe Asp 
        195                 200                 205             


Met Ser Ala Phe Met Ala Gly Pro Gly Asn Ala Lys Lys Val Val Glu 
    210                 215                 220                 


Asn Gly Ala Leu Leu Ser Trp Lys Leu Gly Cys Ser Leu Asn Gln Asn 
225                 230                 235                 240 


Ser Val Pro Asp Ile His Gly Val Glu Ala Pro Ala Arg Glu Gly Ala 
                245                 250                 255     


Met Ser Ala Gln Leu Gly Tyr Pro Val Val Gly Trp His Ile Ala Asn 
            260                 265                 270         


Lys Lys Pro Pro Leu Pro Lys Arg Val Arg Arg Gln Ile His Ala Thr 
        275                 280                 285             


Pro Thr Pro Val Thr Ala Ile Gly Pro Pro Thr Thr Ala Ile Gln Glu 
    290                 295                 300                 


Pro Pro Ser Arg Ile Val Pro Thr Pro Thr Ser Pro Ala Ile Ala Pro 
305                 310                 315                 320 


Pro Thr Glu Thr Met Ala Pro Pro Val Arg Asp Pro Val Pro Gly Lys 
                325                 330                 335     


Pro Thr Val Thr Ile Arg Thr Arg Gly Ala Ile Ile Gln Thr Pro Thr 
            340                 345                 350         


Leu Gly Pro Ile Gln Pro Thr Arg Val Ser Glu Ala Gly Thr Thr Val 
        355                 360                 365             


Pro Gly Gln Ile Arg Pro Thr Met Thr Ile Pro Gly Tyr Val Glu Pro 
    370                 375                 380                 


Thr Ala Val Ala Thr Pro Pro Thr Thr Thr Thr Lys Lys Pro Arg Val 
385                 390                 395                 400 


Ser Thr Pro Lys Pro Ala Thr Pro Ser Thr Asp Ser Thr Thr Thr Thr 
                405                 410                 415     


Thr Arg Arg Pro Thr Lys Lys Pro Arg Thr Pro Arg Pro Val Pro Arg 
            420                 425                 430         


Val Thr Thr Lys Val Ser Ile Thr Arg Leu Glu Thr Ala Ser Pro Pro 
        435                 440                 445             


Thr Arg Ile Arg Thr Thr Thr Ser Gly Val Pro Arg Gly Gly Glu Pro 
    450                 455                 460                 


Asn Gln Arg Pro Glu Leu Lys Asn His Ile Asp Arg Val Asp Ala Trp 
465                 470                 475                 480 


Val Gly Thr Tyr Phe Glu Val Lys Ile Pro Ser Asp Thr Phe Tyr Asp 
                485                 490                 495     


His Glu Asp Thr Thr Thr Asp Lys Leu Lys Leu Thr Leu Lys Leu Arg 
            500                 505                 510         


Glu Gln Gln Leu Val Gly Glu Lys Ser Trp Val Gln Phe Asn Ser Asn 
        515                 520                 525             


Ser Gln Leu Met Tyr Gly Leu Pro Asp Ser Ser His Val Gly Lys His 
    530                 535                 540                 


Glu Tyr Phe Met His Ala Thr Asp Lys Gly Gly Leu Ser Ala Val Asp 
545                 550                 555                 560 


Ala Phe Glu Ile His Val His Arg Arg Pro Gln Gly Asp Arg Ala Pro 
                565                 570                 575     


Ala Arg Phe Lys Ala Lys Phe Val Gly Asp Pro Ala Leu Val Leu Asn 
            580                 585                 590         


Asp Ile His Lys Lys Ile Ala Leu Val Lys Lys Leu Ala Phe Ala Phe 
        595                 600                 605             


Gly Asp Arg Asn Cys Ser Thr Ile Thr Leu Gln Asn Ile Thr Arg Gly 
    610                 615                 620                 


<210>  345
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  345

Arg Pro Glu Pro Gln Ser Pro Arg Pro Gln Ser Trp Ala Ala Ala Asn 
1               5                   10                  15      


Gln Thr Trp Ala Leu Gly Pro Gly Ala Leu Pro Pro Leu Val Pro Ala 
            20                  25                  30          


Ser Ala Leu Gly Ser Trp Lys Ala Phe Leu Gly Leu Gln Lys Ala Arg 
        35                  40                  45              


Gln Leu Gly Met Gly Arg Leu Gln Arg Gly Gln Asp Glu Val Ala Ala 
    50                  55                  60                  


Val Thr Leu Pro Leu Asn Pro Gln Glu Val Ile Gln Gly Met Cys Lys 
65                  70                  75                  80  


Ala Val Pro Phe Val Gln Val Phe Ser Arg Pro Gly Cys Ser Ala Ile 
                85                  90                  95      


Arg Leu Arg Asn His Leu Cys Phe Gly His Cys Ser Ser Leu Tyr Ile 
            100                 105                 110         


Pro Gly Ser Asp Pro Thr Pro Leu Val Leu Cys Asn Ser Cys Met Pro 
        115                 120                 125             


Ala Arg Lys Arg Trp Ala Pro Val Val Leu Trp Cys Leu Thr Gly Ser 
    130                 135                 140                 


Ser Ala Ser Arg Arg Arg Val Lys Ile Ser Thr Met Leu Ile Glu Gly 
145                 150                 155                 160 


Cys His Cys Ser Pro Lys Ala 
                165         


<210>  346
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  346

Asp Glu Ala Ser Gly Ile Gly Pro Glu Val Pro Asp Asp Arg Asp Phe 
1               5                   10                  15      


Glu Pro Ser Leu Gly Pro Val Cys Pro Phe Arg Cys Gln Cys His Leu 
            20                  25                  30          


Arg Val Val Gln Cys Ser Asp Leu Gly Leu Asp Lys Val Pro Lys Asp 
        35                  40                  45              


Leu Pro Pro Asp Thr Thr Leu Leu Asp Leu Gln Asn Asn Lys Ile Thr 
    50                  55                  60                  


Glu Ile Lys Asp Gly Asp Phe Lys Asn Leu Lys Asn Leu His Ala Leu 
65                  70                  75                  80  


Ile Leu Val Asn Asn Lys Ile Ser Lys Val Ser Pro Gly Ala Phe Thr 
                85                  90                  95      


Pro Leu Val Lys Leu Glu Arg Leu Tyr Leu Ser Lys Asn Gln Leu Lys 
            100                 105                 110         


Glu Leu Pro Glu Lys Met Pro Lys Thr Leu Gln Glu Leu Arg Ala His 
        115                 120                 125             


Glu Asn Glu Ile Thr Lys Val Arg Lys Val Thr Phe Asn Gly Leu Asn 
    130                 135                 140                 


Gln Met Ile Val Ile Glu Leu Gly Thr Asn Pro Leu Lys Ser Ser Gly 
145                 150                 155                 160 


Ile Glu Asn Gly Ala Phe Gln Gly Met Lys Lys Leu Ser Tyr Ile Arg 
                165                 170                 175     


Ile Ala Asp Thr Asn Ile Thr Ser Ile Pro Gln Gly Leu Pro Pro Ser 
            180                 185                 190         


Leu Thr Glu Leu His Leu Asp Gly Asn Lys Ile Ser Arg Val Asp Ala 
        195                 200                 205             


Ala Ser Leu Lys Gly Leu Asn Asn Leu Ala Lys Leu Gly Leu Ser Phe 
    210                 215                 220                 


Asn Ser Ile Ser Ala Val Asp Asn Gly Ser Leu Ala Asn Thr Pro His 
225                 230                 235                 240 


Leu Arg Glu Leu His Leu Asp Asn Asn Lys Leu Thr Arg Val Pro Gly 
                245                 250                 255     


Gly Leu Ala Glu His Lys Tyr Ile Gln Val Val Tyr Leu His Asn Asn 
            260                 265                 270         


Asn Ile Ser Val Val Gly Ser Ser Asp Phe Cys Pro Pro Gly His Asn 
        275                 280                 285             


Thr Lys Lys Ala Ser Tyr Ser Gly Val Ser Leu Phe Ser Asn Pro Val 
    290                 295                 300                 


Gln Tyr Trp Glu Ile Gln Pro Ser Thr Phe Arg Cys Val Tyr Val Arg 
305                 310                 315                 320 


Ser Ala Ile Gln Leu Gly Asn Tyr Lys 
                325                 


<210>  347
<211>  236
<212>  PRT
<213>  Homo Sapiens

<400>  347

Arg His Asn Leu Asn Asn Val Ile Ala Ser Leu Gly Cys Thr Val Glu 
1               5                   10                  15      


Leu Gln Ile Asn Asn Thr Arg Ala Ala Trp Arg Ile Ser Thr Ala Pro 
            20                  25                  30          


Leu Arg Ala Met Phe Lys Asp Leu Leu Ser Ser Lys Glu Leu Leu Arg 
        35                  40                  45              


Ala Glu Thr Arg Asn Ile Ser Ala Thr Phe Glu Asp Leu Asp Ala Gln 
    50                  55                  60                  


Val Asn Ser Glu Thr Gly Tyr Thr Pro Glu Asp Thr Met Asp Ser Gly 
65                  70                  75                  80  


Glu Thr Ala Gln Gly Arg Glu Ala Arg Gln Ala Pro Ala Ser Arg Leu 
                85                  90                  95      


His Leu Ser Thr Gln Lys Met Tyr Glu Leu Lys Thr Lys Leu Arg Cys 
            100                 105                 110         


Ser Tyr Val Val Asn Gln Ala Ile Leu Ser Cys Arg Arg Trp Phe Asp 
        115                 120                 125             


Arg Lys His Glu Gln Cys Met Lys His Ile Trp Val Pro Leu Leu Thr 
    130                 135                 140                 


His Leu Leu Cys Leu Pro Met Lys Phe Lys Phe Phe Cys Gly Ile Ala 
145                 150                 155                 160 


Lys Val Met Glu Val Trp Cys Arg Asn Arg Ile Pro Val Glu Gly Asn 
                165                 170                 175     


Phe Gly Gln Thr Tyr Asp Ser Leu Asn Gln Ser Ile Arg Gly Leu Asp 
            180                 185                 190         


Gly Glu Phe Ser Ala Asn Ile Asp Phe Lys Glu Glu Lys Gln Ala Gly 
        195                 200                 205             


Val Leu Gly Leu Asn Thr Ser Trp Glu Arg Val Ser Thr Glu Val Arg 
    210                 215                 220                 


Asp Tyr Val Tyr Arg Gln Glu Ala Arg Leu Glu Trp 
225                 230                 235     


<210>  348
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  348

Lys Gly Leu Leu Asp Gly Met Thr Cys Asn Leu Arg Ala Lys Ser Phe 
1               5                   10                  15      


Ser Ile His Phe Pro Leu Leu Lys Lys Tyr Ile Glu Ala Ile Gln Trp 
            20                  25                  30          


Ile Tyr Gly Leu Ala Thr Pro Leu Ser Val Phe Asp Asp Leu Val Ser 
        35                  40                  45              


Trp Asn Gln Thr Leu Ala Val Ser Leu Phe Ser Pro Ser His Val Leu 
    50                  55                  60                  


Glu Ala Gln Leu Asn Asp Ser Lys Gly Glu Val Leu Ser Val Leu Tyr 
65                  70                  75                  80  


Gln Met Ala Thr Thr Thr Glu Val Leu Ser Ser 
                85                  90      


<210>  349
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  349

Asp Ile Pro Glu Val Val Val Ser Leu Ala Trp Asp Glu Ser Leu Ala 
1               5                   10                  15      


Pro Lys His Pro Gly Ser Arg Lys Asn Met Ala Cys Tyr Cys Arg Ile 
            20                  25                  30          


Pro Ala Cys Ile Ala Gly Glu Arg Arg Tyr Gly Thr Cys Ile Tyr Gln 
        35                  40                  45              


Gly Arg Leu Trp Ala Phe Cys Cys 
    50                  55      


<210>  350
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  350

Ser Gly Val Phe Gln Leu Gln Leu Gln Glu Phe Ile Asn Glu Arg Gly 
1               5                   10                  15      


Val Leu Ala Ser Gly Arg Pro Cys Glu Pro Gly Cys Arg Thr Phe Phe 
            20                  25                  30          


Arg Val Cys Leu Lys His Phe Gln Ala Val Val Ser Pro Gly Pro Cys 
        35                  40                  45              


Thr Phe Gly Thr Val Ser Thr Pro Val Leu Gly Thr Asn Ser Phe Ala 
    50                  55                  60                  


Val Arg Asp Asp Ser Ser Gly Gly Gly Arg Asn Pro Leu Gln Leu Pro 
65                  70                  75                  80  


Phe Asn Phe Thr Trp Pro Gly Thr Phe Ser Leu Ile Ile Glu Ala Trp 
                85                  90                  95      


His Ala Pro Gly Asp Asp Leu Arg Pro Glu Ala Leu Pro Pro Asp Ala 
            100                 105                 110         


Leu Ile Ser Lys Ile Ala Ile Gln Gly Ser Leu Ala Val Gly Gln Asn 
        115                 120                 125             


Trp Leu Leu Asp Glu Gln Thr Ser Thr Leu Thr Arg Leu Arg Tyr Ser 
    130                 135                 140                 


Tyr Arg Val Ile Cys Ser Asp Asn Tyr Tyr Gly Asp Asn Cys Ser Arg 
145                 150                 155                 160 


Leu Cys Lys Lys Arg Asn Asp His Phe Gly His Tyr Val Cys Gln Pro 
                165                 170                 175     


Asp Gly Asn Leu Ser Cys Leu Pro Gly Trp Thr Gly Glu Tyr Cys Gln 
            180                 185                 190         


Gln Pro Ile Cys Leu Ser Gly Cys His Glu Gln Asn Gly Tyr Cys Ser 
        195                 200                 205             


Lys Pro Ala Glu Cys Leu Cys Arg Pro Gly Trp Gln Gly Arg Leu Cys 
    210                 215                 220                 


Asn Glu Cys Ile Pro His Asn Gly Cys Arg His Gly Thr Cys Ser Thr 
225                 230                 235                 240 


Pro Trp Gln Cys Thr Cys Asp Glu Gly Trp Gly Gly Leu Phe Cys Asp 
                245                 250                 255     


Gln Asp Leu Asn Tyr Cys Thr His His Ser Pro Cys Lys Asn Gly Ala 
            260                 265                 270         


Thr Cys Ser Asn Ser Gly Gln Arg Ser Tyr Thr Cys Thr Cys Arg Pro 
        275                 280                 285             


Gly Tyr Thr Gly Val Asp Cys Glu Leu Glu Leu Ser Glu Cys Asp Ser 
    290                 295                 300                 


Asn Pro Cys Arg Asn Gly Gly Ser Cys Lys Asp Gln Glu Asp Gly Tyr 
305                 310                 315                 320 


His Cys Leu Cys Pro Pro Gly Tyr Tyr Gly Leu His Cys Glu His Ser 
                325                 330                 335     


Thr Leu Ser Cys Ala Asp Ser Pro Cys Phe Asn Gly Gly Ser Cys Arg 
            340                 345                 350         


Glu Arg Asn Gln Gly Ala Asn Tyr Ala Cys Glu Cys Pro Pro Asn Phe 
        355                 360                 365             


Thr Gly Ser Asn Cys Glu Lys Lys Val Asp Arg Cys Thr Ser Asn Pro 
    370                 375                 380                 


Cys Ala Asn Gly Gly Gln Cys Leu Asn Arg Gly Pro Ser Arg Met Cys 
385                 390                 395                 400 


Arg Cys Arg Pro Gly Phe Thr Gly Thr Tyr Cys Glu Leu His Val Ser 
                405                 410                 415     


Asp Cys Ala Arg Asn Pro Cys Ala His Gly Gly Thr Cys His Asp Leu 
            420                 425                 430         


Glu Asn Gly Leu Met Cys Thr Cys Pro Ala Gly Phe Ser Gly Arg Arg 
        435                 440                 445             


Cys Glu Val Arg Thr Ser Ile Asp Ala Cys Ala Ser Ser Pro Cys Phe 
    450                 455                 460                 


Asn Arg Ala Thr Cys Tyr Thr Asp Leu Ser Thr Asp Thr Phe Val Cys 
465                 470                 475                 480 


Asn Cys Pro Tyr Gly Phe Val Gly Ser Arg Cys Glu Phe Pro Val Gly 
                485                 490                 495     


Leu Pro Pro Ser 
            500 


<210>  351
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  351

Thr Glu Pro Leu Arg Pro Glu Leu Arg Cys Asn Pro Gly Gln Phe Ala 
1               5                   10                  15      


Cys Arg Ser Gly Thr Ile Gln Cys Ile Pro Leu Pro Trp Gln Cys Asp 
            20                  25                  30          


Gly Trp Ala Thr Cys Glu Asp Glu Ser Asp Glu Ala Asn Cys Pro Glu 
        35                  40                  45              


Val Thr Gly Glu Val Arg Pro His His Gly Lys Glu Ala Val Asp Pro 
    50                  55                  60                  


Arg Gln Gly Arg Ala Arg Gly Gly Asp Pro Ser His Phe His Ala Val 
65                  70                  75                  80  


Asn Val Ala Gln Pro Val Arg Phe Ser Ser Phe Leu Gly Lys Cys Pro 
                85                  90                  95      


Thr Gly Trp His His Tyr Glu Gly Thr Ala Ser Cys Tyr Arg Val Tyr 
            100                 105                 110         


Leu Ser Gly Glu Asn Tyr Trp Asp Ala Ala Gln Thr Cys Gln Arg Leu 
        115                 120                 125             


Asn Gly Ser Leu Ala Thr Phe Ser Thr Asp Gln Glu Leu Arg Phe Val 
    130                 135                 140                 


Leu Ala Gln Glu Trp Asp Gln Pro Glu Arg Ser Phe Gly Trp Lys Asp 
145                 150                 155                 160 


Gln Arg Lys Leu Trp Val Gly Tyr Gln Tyr Val Ile Thr Gly Arg Asn 
                165                 170                 175     


Arg Ser Leu Glu Gly Arg Trp Glu Val Ala Phe Lys Gly Ser Ser Glu 
            180                 185                 190         


Val Phe Leu Pro Pro Asp Pro Ile Phe Ala Ser Ala Met Ser Glu Asn 
        195                 200                 205             


Asp Asn Val Phe Cys Ala Gln Leu Gln Cys Phe His Phe Pro Thr Leu 
    210                 215                 220                 


Arg His His Asp Leu His Ser Trp His Ala Glu Ser Cys Tyr Glu Lys 
225                 230                 235                 240 


Ser Ser Phe Leu Cys Lys Arg Ser Gln Thr Cys Val Asp Ile Lys Asp 
                245                 250                 255     


Asn Val Val Asp Glu Gly Phe Tyr Phe Thr Pro Lys Gly Asp Asp Pro 
            260                 265                 270         


Cys Leu Ser Cys Thr Cys His Gly Gly Glu Pro Glu Met Cys Val Ala 
        275                 280                 285             


Ala Leu Cys Glu Arg Pro Gln Gly Cys Gln Gln Tyr Arg Lys Asp Pro 
    290                 295                 300                 


Lys Glu Cys Cys Lys Phe Met Cys Leu Asp Pro Asp Gly Asn Ser Leu 
305                 310                 315                 320 


Phe Asp Ser Met Ala Ser Gly Met Arg 
                325                 


<210>  352
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  352

Asp Leu Lys Val Glu Met Met Ala Gly Gly Thr Gln Ile Thr Pro Leu 
1               5                   10                  15      


Asn Asp Asn Val Thr Ile Phe Cys Asn Ile Phe Tyr Ser Gln Pro Leu 
            20                  25                  30          


Asn Ile Thr Ser Met Gly Ile Thr Trp Phe Trp Lys Ser Leu Thr Phe 
        35                  40                  45              


Asp Lys Glu Val Lys Val Phe Glu Phe Phe Gly Asp His Gln Glu Ala 
    50                  55                  60                  


Phe Arg Pro Gly Ala Ile Val Ser Pro Trp Arg Leu Lys Ser Gly Asp 
65                  70                  75                  80  


Ala Ser Leu Arg Leu Pro Gly Ile Gln Leu Glu Glu Ala Gly Glu Tyr 
                85                  90                  95      


Arg Cys Glu Val Val Val Thr Pro Leu Lys Ala Gln Gly Thr Val Gln 
            100                 105                 110         


Leu Glu Val Val Ala Ser Pro Ala Ser Arg Leu Leu Leu Asp Gln Val 
        115                 120                 125             


Gly Met Lys Glu Asn Glu Asp Lys Tyr Met Cys Glu Ser Ser Gly Phe 
    130                 135                 140                 


Tyr Pro Glu Ala Ile Asn Ile Thr Trp Glu Lys Gln Thr Gln Lys Phe 
145                 150                 155                 160 


Pro His Pro Ile Glu Ile Ser Glu Asp Val Ile Thr Gly Pro Thr Ile 
                165                 170                 175     


Lys Asn Met Asp Gly Thr Phe Asn Val Thr Ser Cys Leu Lys Leu Asn 
            180                 185                 190         


Ser Ser Gln Glu Asp Pro Gly Thr Val Tyr Gln Cys Val Val Arg His 
        195                 200                 205             


Ala Ser Leu His Thr Pro Leu Arg Ser Asn Phe Thr Leu Thr Ala Ala 
    210                 215                 220                 


Arg His Ser Leu Ser Glu Thr Glu Lys Thr Asp Asn Phe Ser 
225                 230                 235             


<210>  353
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  353

Ala Glu Cys Phe Pro Ala Cys Asn Pro Gln Asn Gly Phe Cys Glu Asp 
1               5                   10                  15      


Asp Asn Val Cys Arg Cys Gln Pro Gly Trp Gln Gly Pro Leu Cys Asp 
            20                  25                  30          


Gln Cys Val Thr Ser Pro Gly Cys Leu His Gly Leu Cys Gly Glu Pro 
        35                  40                  45              


Gly Gln Cys Ile Cys Thr Asp Gly Trp Asp Gly Glu Leu Cys Asp Arg 
    50                  55                  60                  


Asp Val Arg Ala Cys Ser Ser Ala Pro Cys Ala Asn Asn Gly Thr Cys 
65                  70                  75                  80  


Val Ser Leu Asp Asp Gly Leu Tyr Glu Cys Ser Cys Ala Pro Gly Tyr 
                85                  90                  95      


Ser Gly Lys Asp Cys Gln Lys Lys Asp Gly Pro Cys Val Ile Asn Gly 
            100                 105                 110         


Ser Pro Cys Gln His Gly Gly Thr Cys Val Asp Asp Glu Gly Arg Ala 
        115                 120                 125             


Ser His Ala Ser Cys Leu Cys Pro Pro Gly Phe Ser Gly Asn Phe Cys 
    130                 135                 140                 


Glu Ile Val Ala Asn Ser Cys Thr Pro Asn Pro Cys Glu Asn Asp Gly 
145                 150                 155                 160 


Val Cys Thr Asp Ile Gly Gly Asp Phe Arg Cys Arg Cys Pro Ala Gly 
                165                 170                 175     


Phe Ile Asp Lys Thr Cys Ser Arg Pro Val Thr Asn Cys Ala Ser Ser 
            180                 185                 190         


Pro Cys Gln Asn Gly Gly Thr Cys Leu Gln His Thr Gln Val Ser Tyr 
        195                 200                 205             


Glu Cys Leu Cys Lys Pro Glu Phe Thr Gly Leu Thr Cys Val Lys Lys 
    210                 215                 220                 


Arg Ala Leu Ser Pro Gln Gln Val Thr Arg Leu Pro Asn Gly Tyr Gly 
225                 230                 235                 240 


Leu Ala Tyr Arg Leu Thr Pro Gly Val His Glu Leu Pro Val Gln Gln 
                245                 250                 255     


Pro Glu His Arg Ile Leu Lys Val Ser Met Lys Glu Leu Asn Lys Lys 
            260                 265                 270         


Thr Pro Leu Leu Thr Glu Gly Gln 
        275                 280 


<210>  354
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  354

Asp Asp Cys Ser Ser His Cys Asp Leu Ala His Gly Cys Cys Ala Pro 
1               5                   10                  15      


Asp Gly Ser Cys Arg Cys Asp Pro Gly Trp Glu Gly Leu His Cys Glu 
            20                  25                  30          


Arg Cys Val Arg Met Pro Gly Cys Gln His Gly Thr Cys His Gln Pro 
        35                  40                  45              


Trp Gln Cys Ile Cys His Ser Gly Trp Ala Gly Lys Phe Cys Asp Lys 
    50                  55                  60                  


Asp Glu His Ile Cys Thr Thr Gln Ser Pro Cys Gln Asn Gly Gly Gln 
65                  70                  75                  80  


Cys Met Tyr Asp Gly Gly Gly Glu Tyr His Cys Val Cys Leu Pro Gly 
                85                  90                  95      


Phe His Gly Arg Asp Cys Glu Arg Lys Ala Gly Pro Cys Glu Gln Ala 
            100                 105                 110         


Gly Ser Pro Cys Arg Asn Gly Gly Gln Cys Gln Asp Asp Gln Gly Phe 
        115                 120                 125             


Ala Leu Asn Phe Thr Cys Arg Cys Leu Val Gly Phe Val Gly Ala Arg 
    130                 135                 140                 


Cys Glu Val Asn Val Asp Asp Cys Leu Met Arg Pro Cys Ala Asn Gly 
145                 150                 155                 160 


Ala Thr Cys Leu Asp Gly Ile Asn Arg Phe Ser Cys Leu Cys Pro Glu 
                165                 170                 175     


Gly Phe Ala Gly Arg Phe Cys Thr Ile Asn Leu Asp Asp Cys Ala Ser 
            180                 185                 190         


Arg Pro Cys Gln Arg Gly Ala Arg Cys Arg Asp Arg Val His Asp Phe 
        195                 200                 205             


Asp Cys Leu Cys Pro Ser Gly Tyr Gly Gly Lys Thr Cys Glu Leu Val 
    210                 215                 220                 


Leu Pro Val Pro Asp Pro Pro Thr Thr Val Asp Thr Pro Leu Gly Pro 
225                 230                 235                 240 


Thr Ser Ala Val Val Val Pro Ala Thr Gly Pro Ala Pro His Ser Ala 
                245                 250                 255     


Gly Ala Gly Leu Leu Arg Ile Ser Val Lys Glu Val Val Arg Arg Gln 
            260                 265                 270         


Glu Ala Gly Leu Gly Glu Pro Ser 
        275                 280 


<210>  355
<211>  528
<212>  PRT
<213>  Homo Sapiens

<400>  355

Gln Val Trp Ser Ser Gly Val Phe Glu Leu Lys Leu Gln Glu Phe Val 
1               5                   10                  15      


Asn Lys Lys Gly Leu Leu Gly Asn Arg Asn Cys Cys Arg Gly Gly Ala 
            20                  25                  30          


Gly Pro Pro Pro Cys Ala Cys Arg Thr Phe Phe Arg Val Cys Leu Lys 
        35                  40                  45              


His Tyr Gln Ala Ser Val Ser Pro Glu Pro Pro Cys Thr Tyr Gly Ser 
    50                  55                  60                  


Ala Val Thr Pro Val Leu Gly Val Asp Ser Phe Ser Leu Pro Asp Gly 
65                  70                  75                  80  


Gly Gly Ala Asp Ser Ala Phe Ser Asn Pro Ile Arg Phe Pro Phe Gly 
                85                  90                  95      


Phe Thr Trp Pro Gly Thr Phe Ser Leu Ile Ile Glu Ala Leu His Thr 
            100                 105                 110         


Asp Ser Pro Asp Asp Leu Ala Thr Glu Asn Pro Glu Arg Leu Ile Ser 
        115                 120                 125             


Arg Leu Ala Thr Gln Arg His Leu Thr Val Gly Glu Glu Trp Ser Gln 
    130                 135                 140                 


Asp Leu His Ser Ser Gly Arg Thr Asp Leu Lys Tyr Ser Tyr Arg Phe 
145                 150                 155                 160 


Val Cys Asp Glu His Tyr Tyr Gly Glu Gly Cys Ser Val Phe Cys Arg 
                165                 170                 175     


Pro Arg Asp Asp Ala Phe Gly His Phe Thr Cys Gly Glu Arg Gly Glu 
            180                 185                 190         


Lys Val Cys Asn Pro Gly Trp Lys Gly Pro Tyr Cys Thr Glu Pro Ile 
        195                 200                 205             


Cys Leu Pro Gly Cys Asp Glu Gln His Gly Phe Cys Asp Lys Pro Gly 
    210                 215                 220                 


Glu Cys Lys Cys Arg Val Gly Trp Gln Gly Arg Tyr Cys Asp Glu Cys 
225                 230                 235                 240 


Ile Arg Tyr Pro Gly Cys Leu His Gly Thr Cys Gln Gln Pro Trp Gln 
                245                 250                 255     


Cys Asn Cys Gln Glu Gly Trp Gly Gly Leu Phe Cys Asn Gln Asp Leu 
            260                 265                 270         


Asn Tyr Cys Thr His His Lys Pro Cys Lys Asn Gly Ala Thr Cys Thr 
        275                 280                 285             


Asn Thr Gly Gln Gly Ser Tyr Thr Cys Ser Cys Arg Pro Gly Tyr Thr 
    290                 295                 300                 


Gly Ala Thr Cys Glu Leu Gly Ile Asp Glu Cys Asp Pro Ser Pro Cys 
305                 310                 315                 320 


Lys Asn Gly Gly Ser Cys Thr Asp Leu Glu Asn Ser Tyr Ser Cys Thr 
                325                 330                 335     


Cys Pro Pro Gly Phe Tyr Gly Lys Ile Cys Glu Leu Ser Ala Met Thr 
            340                 345                 350         


Cys Ala Asp Gly Pro Cys Phe Asn Gly Gly Arg Cys Ser Asp Ser Pro 
        355                 360                 365             


Asp Gly Gly Tyr Ser Cys Arg Cys Pro Val Gly Tyr Ser Gly Phe Asn 
    370                 375                 380                 


Cys Glu Lys Lys Ile Asp Tyr Cys Ser Ser Ser Pro Cys Ser Asn Gly 
385                 390                 395                 400 


Ala Lys Cys Val Asp Leu Gly Asp Ala Tyr Leu Cys Arg Cys Gln Ala 
                405                 410                 415     


Gly Phe Ser Gly Arg His Cys Asp Asp Asn Val Asp Asp Cys Ala Ser 
            420                 425                 430         


Ser Pro Cys Ala Asn Gly Gly Thr Cys Arg Asp Gly Val Asn Asp Phe 
        435                 440                 445             


Ser Cys Thr Cys Pro Pro Gly Tyr Thr Gly Arg Asn Cys Ser Ala Pro 
    450                 455                 460                 


Val Ser Arg Cys Glu His Ala Pro Cys His Asn Gly Ala Thr Cys His 
465                 470                 475                 480 


Glu Arg Gly His Arg Tyr Val Cys Glu Cys Ala Arg Gly Tyr Gly Gly 
                485                 490                 495     


Pro Asn Cys Gln Phe Leu Leu Pro Glu Leu Pro Pro Gly Pro Ala Val 
            500                 505                 510         


Val Asp Leu Thr Glu Lys Leu Glu Gly Gln Gly Gly Pro Phe Pro Trp 
        515                 520                 525             


<210>  356
<211>  466
<212>  PRT
<213>  Homo Sapiens

<400>  356

Ala Gly Val Phe Glu Leu Gln Ile His Ser Phe Gly Pro Gly Pro Gly 
1               5                   10                  15      


Pro Gly Ala Pro Arg Ser Pro Cys Ser Ala Arg Leu Pro Cys Arg Leu 
            20                  25                  30          


Phe Phe Arg Val Cys Leu Lys Pro Gly Leu Ser Glu Glu Ala Ala Glu 
        35                  40                  45              


Ser Pro Cys Ala Leu Gly Ala Ala Leu Ser Ala Arg Gly Pro Val Tyr 
    50                  55                  60                  


Thr Glu Gln Pro Gly Ala Pro Ala Pro Asp Leu Pro Leu Pro Asp Gly 
65                  70                  75                  80  


Leu Leu Gln Val Pro Phe Arg Asp Ala Trp Pro Gly Thr Phe Ser Phe 
                85                  90                  95      


Ile Ile Glu Thr Trp Arg Glu Glu Leu Gly Asp Gln Ile Gly Gly Pro 
            100                 105                 110         


Ala Trp Ser Leu Leu Ala Arg Val Ala Gly Arg Arg Arg Leu Ala Ala 
        115                 120                 125             


Gly Gly Pro Trp Ala Arg Asp Ile Gln Arg Ala Gly Ala Trp Glu Leu 
    130                 135                 140                 


Arg Phe Ser Tyr Arg Ala Arg Cys Glu Pro Pro Ala Val Gly Thr Ala 
145                 150                 155                 160 


Cys Thr Arg Leu Cys Arg Pro Arg Ser Ala Pro Ser Arg Cys Gly Pro 
                165                 170                 175     


Gly Leu Arg Pro Cys Ala Pro Leu Glu Asp Glu Cys Glu Ala Pro Leu 
            180                 185                 190         


Val Cys Arg Ala Gly Cys Ser Pro Glu His Gly Phe Cys Glu Gln Pro 
        195                 200                 205             


Gly Glu Cys Arg Cys Leu Glu Gly Trp Thr Gly Pro Leu Cys Thr Val 
    210                 215                 220                 


Pro Val Ser Thr Ser Ser Cys Leu Ser Pro Arg Gly Pro Ser Ser Ala 
225                 230                 235                 240 


Thr Thr Gly Cys Leu Val Pro Gly Pro Gly Pro Cys Asp Gly Asn Pro 
                245                 250                 255     


Cys Ala Asn Gly Gly Ser Cys Ser Glu Thr Pro Arg Ser Phe Glu Cys 
            260                 265                 270         


Thr Cys Pro Arg Gly Phe Tyr Gly Leu Arg Cys Glu Val Ser Gly Val 
        275                 280                 285             


Thr Cys Ala Asp Gly Pro Cys Phe Asn Gly Gly Leu Cys Val Gly Gly 
    290                 295                 300                 


Ala Asp Pro Asp Ser Ala Tyr Ile Cys His Cys Pro Pro Gly Phe Gln 
305                 310                 315                 320 


Gly Ser Asn Cys Glu Lys Arg Val Asp Arg Cys Ser Leu Gln Pro Cys 
                325                 330                 335     


Arg Asn Gly Gly Leu Cys Leu Asp Leu Gly His Ala Leu Arg Cys Arg 
            340                 345                 350         


Cys Arg Ala Gly Phe Ala Gly Pro Arg Cys Glu His Asp Leu Asp Asp 
        355                 360                 365             


Cys Ala Gly Arg Ala Cys Ala Asn Gly Gly Thr Cys Val Glu Gly Gly 
    370                 375                 380                 


Gly Ala His Arg Cys Ser Cys Ala Leu Gly Phe Gly Gly Arg Asp Cys 
385                 390                 395                 400 


Arg Glu Arg Ala Asp Pro Cys Ala Ala Arg Pro Cys Ala His Gly Gly 
                405                 410                 415     


Arg Cys Tyr Ala His Phe Ser Gly Leu Val Cys Ala Cys Ala Pro Gly 
            420                 425                 430         


Tyr Met Gly Ala Arg Cys Glu Phe Pro Val His Pro Asp Gly Ala Ser 
        435                 440                 445             


Ala Leu Pro Ala Ala Pro Pro Gly Leu Arg Pro Gly Asp Pro Gln Arg 
    450                 455                 460                 


Tyr Leu 
465     


<210>  357
<211>  503
<212>  PRT
<213>  Homo Sapiens

<400>  357

Ser Gly Val Phe Gln Leu Gln Leu Gln Glu Phe Ile Asn Glu Arg Gly 
1               5                   10                  15      


Val Leu Ala Ser Gly Arg Pro Cys Glu Pro Gly Cys Arg Thr Phe Phe 
            20                  25                  30          


Arg Val Cys Leu Lys His Phe Gln Ala Val Val Ser Pro Gly Pro Cys 
        35                  40                  45              


Thr Phe Gly Thr Val Ser Thr Pro Val Leu Gly Thr Asn Ser Phe Ala 
    50                  55                  60                  


Val Arg Asp Asp Ser Ser Gly Gly Gly Arg Asn Pro Leu Gln Leu Pro 
65                  70                  75                  80  


Phe Asn Phe Thr Trp Pro Gly Thr Phe Ser Leu Ile Ile Glu Ala Trp 
                85                  90                  95      


His Ala Pro Gly Asp Asp Leu Arg Pro Glu Ala Leu Pro Pro Asp Ala 
            100                 105                 110         


Leu Ile Ser Lys Ile Ala Ile Gln Gly Ser Leu Ala Val Gly Gln Asn 
        115                 120                 125             


Trp Leu Leu Asp Glu Gln Thr Ser Thr Leu Thr Arg Leu Arg Tyr Ser 
    130                 135                 140                 


Tyr Arg Val Ile Cys Ser Asp Asn Tyr Tyr Gly Asp Asn Cys Ser Arg 
145                 150                 155                 160 


Leu Cys Lys Lys Arg Asn Asp His Phe Gly His Tyr Val Cys Gln Pro 
                165                 170                 175     


Asp Gly Asn Leu Ser Cys Leu Pro Gly Trp Thr Gly Glu Tyr Cys Gln 
            180                 185                 190         


Gln Pro Ile Cys Leu Ser Gly Cys His Glu Gln Asn Gly Tyr Cys Ser 
        195                 200                 205             


Lys Pro Ala Glu Cys Leu Cys Arg Pro Gly Trp Gln Gly Arg Leu Cys 
    210                 215                 220                 


Asn Glu Cys Ile Pro His Asn Gly Cys Arg His Gly Thr Cys Ser Thr 
225                 230                 235                 240 


Pro Trp Gln Cys Thr Cys Asp Glu Gly Trp Gly Gly Leu Phe Cys Asp 
                245                 250                 255     


Gln Asp Leu Asn Tyr Cys Thr His His Ser Pro Cys Lys Asn Gly Ala 
            260                 265                 270         


Thr Cys Ser Asn Ser Gly Gln Arg Ser Tyr Thr Cys Thr Cys Arg Pro 
        275                 280                 285             


Gly Tyr Thr Gly Val Asp Cys Glu Leu Glu Leu Ser Glu Cys Asp Ser 
    290                 295                 300                 


Asn Pro Cys Arg Asn Gly Gly Ser Cys Lys Asp Gln Glu Asp Gly Tyr 
305                 310                 315                 320 


His Cys Leu Cys Pro Pro Gly Tyr Tyr Gly Leu His Cys Glu His Ser 
                325                 330                 335     


Thr Leu Ser Cys Ala Asp Ser Pro Cys Phe Asn Gly Gly Ser Cys Arg 
            340                 345                 350         


Glu Arg Asn Gln Gly Ala Asn Tyr Ala Cys Glu Cys Pro Pro Asn Phe 
        355                 360                 365             


Thr Gly Ser Asn Cys Glu Lys Lys Val Asp Arg Cys Thr Ser Asn Pro 
    370                 375                 380                 


Cys Ala Asn Gly Gly Gln Cys Leu Asn Arg Gly Pro Ser Arg Met Cys 
385                 390                 395                 400 


Arg Cys Arg Pro Gly Phe Thr Gly Thr Tyr Cys Glu Leu His Val Ser 
                405                 410                 415     


Asp Cys Ala Arg Asn Pro Cys Ala His Gly Gly Thr Cys His Asp Leu 
            420                 425                 430         


Glu Asn Gly Leu Met Cys Thr Cys Pro Ala Gly Phe Ser Gly Arg Arg 
        435                 440                 445             


Cys Glu Val Arg Thr Ser Ile Asp Ala Cys Ala Ser Ser Pro Cys Phe 
    450                 455                 460                 


Asn Arg Ala Thr Cys Tyr Thr Asp Leu Ser Thr Asp Thr Phe Val Cys 
465                 470                 475                 480 


Asn Cys Pro Tyr Gly Phe Val Gly Ser Arg Cys Glu Phe Pro Val Gly 
                485                 490                 495     


Leu Pro Pro Ser Phe Pro Trp 
            500             


<210>  358
<211>  606
<212>  PRT
<213>  Homo Sapiens

<400>  358

Asn Pro Val Pro Ala Ala Pro Leu Ser Ala Pro Gly Pro Cys Ala Ala 
1               5                   10                  15      


Gln Pro Cys Arg Asn Gly Gly Val Cys Thr Ser Arg Pro Glu Pro Asp 
            20                  25                  30          


Pro Gln His Pro Ala Pro Ala Gly Glu Pro Gly Tyr Ser Cys Thr Cys 
        35                  40                  45              


Pro Ala Gly Ile Ser Gly Ala Asn Cys Gln Leu Val Ala Asp Pro Cys 
    50                  55                  60                  


Ala Ser Asn Pro Cys His His Gly Asn Cys Ser Ser Ser Ser Ser Ser 
65                  70                  75                  80  


Ser Ser Asp Gly Tyr Leu Cys Ile Cys Asn Glu Gly Tyr Glu Gly Pro 
                85                  90                  95      


Asn Cys Glu Gln Ala Leu Pro Ser Leu Pro Ala Thr Gly Trp Thr Glu 
            100                 105                 110         


Ser Met Ala Pro Arg Gln Leu Gln Pro Val Pro Ala Thr Gln Glu Pro 
        115                 120                 125             


Asp Lys Ile Leu Pro Arg Ser Gln Ala Thr Val Thr Leu Pro Thr Trp 
    130                 135                 140                 


Gln Pro Lys Thr Gly Gln Lys Val Val Glu Met Lys Trp Asp Gln Val 
145                 150                 155                 160 


Glu Val Ile Pro Asp Ile Ala Cys Gly Asn Ala Ser Ser Asn Ser Ser 
                165                 170                 175     


Ala Gly Gly Arg Leu Val Ser Phe Glu Val Pro Gln Asn Thr Ser Val 
            180                 185                 190         


Lys Ile Arg Gln Asp Ala Thr Ala Ser Leu Ile Leu Leu Trp Lys Val 
        195                 200                 205             


Thr Ala Thr Gly Phe Gln Gln Cys Ser Leu Ile Asp Gly Arg Ser Val 
    210                 215                 220                 


Thr Pro Leu Gln Ala Ser Gly Gly Leu Val Leu Leu Glu Glu Met Leu 
225                 230                 235                 240 


Ala Leu Gly Asn Asn His Phe Ile Gly Phe Val Asn Asp Ser Val Thr 
                245                 250                 255     


Lys Ser Ile Val Ala Leu Arg Leu Thr Leu Val Val Lys Val Ser Thr 
            260                 265                 270         


Cys Val Pro Gly Glu Ser His Ala Asn Asp Leu Glu Cys Ser Gly Lys 
        275                 280                 285             


Gly Lys Cys Thr Thr Lys Pro Ser Glu Ala Thr Phe Ser Cys Thr Cys 
    290                 295                 300                 


Glu Glu Gln Tyr Val Gly Thr Phe Cys Glu Glu Tyr Asp Ala Cys Gln 
305                 310                 315                 320 


Arg Lys Pro Cys Gln Asn Asn Ala Ser Cys Ile Asp Ala Asn Glu Lys 
                325                 330                 335     


Gln Asp Gly Ser Asn Phe Thr Cys Val Cys Leu Pro Gly Tyr Thr Gly 
            340                 345                 350         


Glu Leu Cys Gln Ser Lys Ile Asp Tyr Cys Ile Leu Asp Pro Cys Arg 
        355                 360                 365             


Asn Gly Ala Thr Cys Ile Ser Ser Leu Ser Gly Phe Thr Cys Gln Cys 
    370                 375                 380                 


Pro Glu Gly Tyr Phe Gly Ser Ala Cys Glu Glu Lys Val Asp Leu Cys 
385                 390                 395                 400 


Ala Ser Ser Pro Cys Gln Asn Asn Gly Thr Cys Tyr Val Asp Gly Val 
                405                 410                 415     


His Phe Thr Cys Asn Cys Ser Pro Gly Phe Thr Gly Pro Thr Cys Ala 
            420                 425                 430         


Gln Leu Ile Asp Phe Cys Ala Leu Ser Pro Cys Ala His Gly Thr Cys 
        435                 440                 445             


Arg Ser Val Gly Thr Ser Tyr Lys Cys Leu Cys Asp Pro Gly Tyr His 
    450                 455                 460                 


Gly Leu Tyr Cys Glu Glu Glu Tyr Asn Glu Cys Leu Ser Ala Pro Cys 
465                 470                 475                 480 


Leu Asn Ala Ala Thr Cys Arg Asp Leu Val Asn Gly Tyr Glu Cys Val 
                485                 490                 495     


Cys Leu Ala Glu Tyr Lys Gly Thr His Cys Glu Leu Tyr Lys Asp Pro 
            500                 505                 510         


Cys Ala Asn Val Ser Cys Leu Asn Gly Ala Thr Cys Asp Ser Asp Gly 
        515                 520                 525             


Leu Asn Gly Thr Cys Ile Cys Ala Pro Gly Phe Thr Gly Glu Glu Cys 
    530                 535                 540                 


Asp Ile Asp Ile Asn Glu Cys Asp Ser Asn Pro Cys His His Gly Gly 
545                 550                 555                 560 


Ser Cys Leu Asp Gln Pro Asn Gly Tyr Asn Cys His Cys Pro His Gly 
                565                 570                 575     


Trp Val Gly Ala Asn Cys Glu Ile His Leu Gln Trp Lys Ser Gly His 
            580                 585                 590         


Met Ala Glu Ser Leu Thr Asn Met Pro Arg His Ser Leu Tyr 
        595                 600                 605     


<210>  359
<211>  559
<212>  PRT
<213>  Homo Sapiens

<400>  359

Arg Trp Ala Pro Ile Pro Cys Ser Met Leu Glu Asn Ser Leu Gly Pro 
1               5                   10                  15      


Phe Pro Leu Phe Leu Gln Gln Val Gln Ser Asp Thr Ala Gln Asn Tyr 
            20                  25                  30          


Thr Ile Tyr Tyr Ser Ile Arg Gly Pro Gly Val Asp Gln Glu Pro Arg 
        35                  40                  45              


Asn Leu Phe Tyr Val Glu Arg Asp Thr Gly Asn Leu Tyr Cys Thr Arg 
    50                  55                  60                  


Pro Val Asp Arg Glu Gln Tyr Glu Ser Phe Glu Ile Ile Ala Phe Ala 
65                  70                  75                  80  


Thr Thr Pro Asp Gly Tyr Thr Pro Glu Leu Pro Leu Pro Leu Ile Ile 
                85                  90                  95      


Lys Ile Glu Asp Glu Asn Asp Asn Tyr Pro Ile Phe Thr Glu Glu Thr 
            100                 105                 110         


Tyr Thr Phe Thr Ile Phe Glu Asn Cys Arg Val Gly Thr Thr Val Gly 
        115                 120                 125             


Gln Val Cys Ala Thr Asp Lys Asp Glu Pro Asp Thr Met His Thr Arg 
    130                 135                 140                 


Leu Lys Tyr Ser Ile Ile Gly Gln Val Pro Pro Ser Pro Thr Leu Phe 
145                 150                 155                 160 


Ser Met His Pro Thr Thr Gly Val Ile Thr Thr Thr Ser Ser Gln Leu 
                165                 170                 175     


Asp Arg Glu Leu Ile Asp Lys Tyr Gln Leu Lys Ile Lys Val Gln Asp 
            180                 185                 190         


Met Asp Gly Gln Tyr Phe Gly Leu Gln Thr Thr Ser Thr Cys Ile Ile 
        195                 200                 205             


Asn Ile Asp Asp Val Asn Asp His Leu Pro Thr Phe Thr Arg Thr Ser 
    210                 215                 220                 


Tyr Val Thr Ser Val Glu Glu Asn Thr Val Asp Val Glu Ile Leu Arg 
225                 230                 235                 240 


Val Thr Val Glu Asp Lys Asp Leu Val Asn Thr Ala Asn Trp Arg Ala 
                245                 250                 255     


Asn Tyr Thr Ile Leu Lys Gly Asn Glu Asn Gly Asn Phe Lys Ile Val 
            260                 265                 270         


Thr Asp Ala Lys Thr Asn Glu Gly Val Leu Cys Val Val Lys Pro Leu 
        275                 280                 285             


Asn Tyr Glu Glu Lys Gln Gln Met Ile Leu Gln Ile Gly Val Val Asn 
    290                 295                 300                 


Glu Ala Pro Phe Ser Arg Glu Ala Ser Pro Arg Ser Ala Met Ser Thr 
305                 310                 315                 320 


Ala Thr Val Thr Val Asn Val Glu Asp Gln Asp Glu Gly Pro Glu Cys 
                325                 330                 335     


Asn Pro Pro Ile Gln Thr Val Arg Met Lys Glu Asn Ala Glu Val Gly 
            340                 345                 350         


Thr Thr Ser Asn Gly Tyr Lys Ala Tyr Asp Pro Glu Thr Arg Ser Ser 
        355                 360                 365             


Ser Gly Ile Arg Tyr Lys Lys Leu Thr Asp Pro Thr Gly Trp Val Thr 
    370                 375                 380                 


Ile Asp Glu Asn Thr Gly Ser Ile Lys Val Phe Arg Ser Leu Asp Arg 
385                 390                 395                 400 


Glu Ala Glu Thr Ile Lys Asn Gly Ile Tyr Asn Ile Thr Val Leu Ala 
                405                 410                 415     


Ser Asp Gln Gly Gly Arg Thr Cys Thr Gly Thr Leu Gly Ile Ile Leu 
            420                 425                 430         


Gln Asp Val Asn Asp Asn Ser Pro Phe Ile Pro Lys Lys Thr Val Ile 
        435                 440                 445             


Ile Cys Lys Pro Thr Met Ser Ser Ala Glu Ile Val Ala Val Asp Pro 
    450                 455                 460                 


Asp Glu Pro Ile His Gly Pro Pro Phe Asp Phe Ser Leu Glu Ser Ser 
465                 470                 475                 480 


Thr Ser Glu Val Gln Arg Met Trp Arg Leu Lys Ala Ile Asn Asp Thr 
                485                 490                 495     


Ala Ala Arg Leu Ser Tyr Gln Asn Asp Pro Pro Phe Gly Ser Tyr Val 
            500                 505                 510         


Val Pro Ile Thr Val Arg Asp Arg Leu Gly Met Ser Ser Val Thr Ser 
        515                 520                 525             


Leu Asp Val Thr Leu Cys Asp Cys Ile Thr Glu Asn Asp Cys Thr His 
    530                 535                 540                 


Arg Val Asp Pro Arg Ile Gly Gly Gly Gly Val Gln Leu Gly Lys 
545                 550                 555                 


<210>  360
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  360

Arg Trp Ala Pro Ile Pro Cys Ser Met Gln Glu Asn Ser Leu Gly Pro 
1               5                   10                  15      


Phe Pro Leu Phe Leu Gln Gln Val Glu Ser Asp Ala Ala Gln Asn Tyr 
            20                  25                  30          


Thr Val Phe Tyr Ser Ile Ser Gly Arg Gly Val Asp Lys Glu Pro Leu 
        35                  40                  45              


Asn Leu Phe Tyr Ile Glu Arg Asp Thr Gly Asn Leu Phe Cys Thr Arg 
    50                  55                  60                  


Pro Val Asp Arg Glu Glu Tyr Asp Val Phe Asp Leu Ile Ala Tyr Ala 
65                  70                  75                  80  


Ser Thr Ala Asp Gly Tyr Ser Ala Asp Leu Pro Leu Pro Leu Pro Ile 
                85                  90                  95      


Arg Val Glu Asp Glu Asn Asp Asn His Pro Val Phe Thr Glu Ala Ile 
            100                 105                 110         


Tyr Asn Phe Glu Val Leu Glu Ser Ser Arg Pro Gly Thr Thr Val Gly 
        115                 120                 125             


Val Val Cys Ala Thr Asp Arg Asp Glu Pro Asp Thr Met His Thr Arg 
    130                 135                 140                 


Leu Lys Tyr Ser Ile Leu Gln Gln Thr Pro Arg Ser Pro Gly Leu Phe 
145                 150                 155                 160 


Ser Val His Pro Ser Thr Gly Val Ile Thr Thr Val Ser His Tyr Leu 
                165                 170                 175     


Asp Arg Glu Val Val Asp Lys Tyr Ser Leu Ile Met Lys Val Gln Asp 
            180                 185                 190         


Met Asp Gly Gln Phe Phe Gly Leu Ile Gly Thr Ser Thr Cys Ile Ile 
        195                 200                 205             


Thr Val Thr Asp Ser Asn Asp Asn Ala Pro Thr Phe Arg Gln Asn Ala 
    210                 215                 220                 


Tyr Glu Ala Phe Val Glu Glu Asn Ala Phe Asn Val Glu Ile Leu Arg 
225                 230                 235                 240 


Ile Pro Ile Glu Asp Lys Asp Leu Ile Asn Thr Ala Asn Trp Arg Val 
                245                 250                 255     


Asn Phe Thr Ile Leu Lys Gly Asn Glu Asn Gly His Phe Lys Ile Ser 
            260                 265                 270         


Thr Asp Lys Glu Thr Asn Glu Gly Val Leu Ser Val Val Lys Pro Leu 
        275                 280                 285             


Asn Tyr Glu Glu Asn Arg Gln Val Asn Leu Glu Ile Gly Val Asn Asn 
    290                 295                 300                 


Glu Ala Pro Phe Ala Arg Asp Ile Pro Arg Val Thr Ala Leu Asn Arg 
305                 310                 315                 320 


Ala Leu Val Thr Val His Val Arg Asp Leu Asp Glu Gly Pro Glu Cys 
                325                 330                 335     


Thr Pro Ala Ala Gln Tyr Val Arg Ile Lys Glu Asn Leu Ala Val Gly 
            340                 345                 350         


Ser Lys Ile Asn Gly Tyr Lys Ala Tyr Asp Pro Glu Asn Arg Asn Gly 
        355                 360                 365             


Asn Gly Leu Arg Tyr Lys Lys Leu His Asp Pro Lys Gly Trp Ile Thr 
    370                 375                 380                 


Ile Asp Glu Ile Ser Gly Ser Ile Ile Thr Ser Lys Ile Leu Asp Arg 
385                 390                 395                 400 


Glu Val Glu Thr Pro Lys Asn Glu Leu Tyr Asn Ile Thr Val Leu Ala 
                405                 410                 415     


Ile Asp Lys Asp Asp Arg Ser Cys Thr Gly Thr Leu Ala Val Asn Ile 
            420                 425                 430         


Glu Asp Val Asn Asp Asn Pro Pro Glu Ile Leu Gln Glu Tyr Val Val 
        435                 440                 445             


Ile Cys Lys Pro Lys Met Gly Tyr Thr Asp Ile Leu Ala Val Asp Pro 
    450                 455                 460                 


Asp Glu Pro Val His Gly Ala Pro Phe Tyr Phe Ser Leu Pro Asn Thr 
465                 470                 475                 480 


Ser Pro Glu Ile Ser Arg Leu Trp Ser Leu Thr Lys Val Asn Asp Thr 
                485                 490                 495     


Ala Ala Arg Leu Ser Tyr Gln Lys Asn Ala Gly Phe Gln Glu Tyr Thr 
            500                 505                 510         


Ile Pro Ile Thr Val Lys Asp Arg Ala Gly Gln Ala Ala Thr Lys Leu 
        515                 520                 525             


Leu Arg Val Asn Leu Cys Glu Cys Thr His Pro Thr Gln Cys Arg Ala 
    530                 535                 540                 


Thr Ser Arg Ser Thr Gly Val Ile Leu Gly Lys 
545                 550                 555 


<210>  361
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  361

Ala Trp Ile Thr Ala Pro Val Ala Leu Arg Glu Gly Glu Asp Leu Ser 
1               5                   10                  15      


Lys Lys Asn Pro Ile Ala Lys Ile His Ser Asp Leu Ala Glu Glu Arg 
            20                  25                  30          


Gly Leu Lys Ile Thr Tyr Lys Tyr Thr Gly Lys Gly Ile Thr Glu Pro 
        35                  40                  45              


Pro Phe Gly Ile Phe Val Phe Asn Lys Asp Thr Gly Glu Leu Asn Val 
    50                  55                  60                  


Thr Ser Ile Leu Asp Arg Glu Glu Thr Pro Phe Phe Leu Leu Thr Gly 
65                  70                  75                  80  


Tyr Ala Leu Asp Ala Arg Gly Asn Asn Val Glu Lys Pro Leu Glu Leu 
                85                  90                  95      


Arg Ile Lys Val Leu Asp Ile Asn Asp Asn Glu Pro Val Phe Thr Gln 
            100                 105                 110         


Asp Val Phe Val Gly Ser Val Glu Glu Leu Ser Ala Ala His Thr Leu 
        115                 120                 125             


Val Met Lys Ile Asn Ala Thr Asp Ala Asp Glu Pro Asn Thr Leu Asn 
    130                 135                 140                 


Ser Lys Ile Ser Tyr Arg Ile Val Ser Leu Glu Pro Ala Tyr Pro Pro 
145                 150                 155                 160 


Val Phe Tyr Leu Asn Lys Asp Thr Gly Glu Ile Tyr Thr Thr Ser Val 
                165                 170                 175     


Thr Leu Asp Arg Glu Glu His Ser Ser Tyr Thr Leu Thr Val Glu Ala 
            180                 185                 190         


Arg Asp Gly Asn Gly Glu Val Thr Asp Lys Pro Val Lys Gln Ala Gln 
        195                 200                 205             


Val Gln Ile Arg Ile Leu Asp Val Asn Asp Asn Ile Pro Val Val Glu 
    210                 215                 220                 


Asn Lys Val Leu Glu Gly Met Val Glu Glu Asn Gln Val Asn Val Glu 
225                 230                 235                 240 


Val Thr Arg Ile Lys Val Phe Asp Ala Asp Glu Ile Gly Ser Asp Asn 
                245                 250                 255     


Trp Leu Ala Asn Phe Thr Phe Ala Ser Gly Asn Glu Gly Gly Tyr Phe 
            260                 265                 270         


His Ile Glu Thr Asp Ala Gln Thr Asn Glu Gly Ile Val Thr Leu Ile 
        275                 280                 285             


Lys Glu Val Asp Tyr Glu Glu Met Lys Asn Leu Asp Phe Ser Val Ile 
    290                 295                 300                 


Val Ala Asn Lys Ala Ala Phe His Lys Ser Ile Arg Ser Lys Tyr Lys 
305                 310                 315                 320 


Pro Thr Pro Ile Pro Ile Lys Val Lys Val Lys Asn Val Lys Glu Gly 
                325                 330                 335     


Ile His Phe Lys Ser Ser Val Ile Ser Ile Tyr Val Ser Glu Ser Met 
            340                 345                 350         


Asp Arg Ser Ser Lys Gly Gln Ile Ile Gly Asn Phe Gln Ala Phe Asp 
        355                 360                 365             


Glu Asp Thr Gly Leu Pro Ala His Ala Arg Tyr Val Lys Leu Glu Asp 
    370                 375                 380                 


Arg Asp Asn Trp Ile Ser Val Asp Ser Val Thr Ser Glu Ile Lys Leu 
385                 390                 395                 400 


Ala Lys Leu Pro Asp Phe Glu Ser Arg Tyr Val Gln Asn Gly Thr Tyr 
                405                 410                 415     


Thr Val Lys Ile Val Ala Ile Ser Glu Asp Tyr Pro Arg Lys Thr Ile 
            420                 425                 430         


Thr Gly Thr Val Leu Ile Asn Val Glu Asp Ile Asn Asp Asn Cys Pro 
        435                 440                 445             


Thr Leu Ile Glu Pro Val Gln Thr Ile Cys His Asp Ala Glu Tyr Val 
    450                 455                 460                 


Asn Val Thr Ala Glu Asp Leu Asp Gly His Pro Asn Ser Gly Pro Phe 
465                 470                 475                 480 


Ser Phe Ser Val Ile Asp Lys Pro Pro Gly Met Ala Glu Lys Trp Lys 
                485                 490                 495     


Ile Ala Arg Gln Glu Ser Thr Ser Val Leu Leu Gln Gln Ser Glu Lys 
            500                 505                 510         


Lys Leu Gly Arg Ser Glu Ile Gln Phe Leu Ile Ser Asp Asn Gln Gly 
        515                 520                 525             


Phe Ser Cys Pro Glu Lys Gln Val Leu Thr Leu Thr Val Cys Glu Cys 
    530                 535                 540                 


Leu His Gly Ser Gly Cys Arg Glu Ala Gln His Asp Ser Tyr Val Gly 
545                 550                 555                 560 


<210>  362
<211>  566
<212>  PRT
<213>  Homo Sapiens

<400>  362

Glu Trp Val Lys Phe Ala Lys Pro Cys Arg Glu Gly Glu Asp Asn Ser 
1               5                   10                  15      


Lys Arg Asn Pro Ile Ala Lys Ile Thr Ser Asp Tyr Gln Ala Thr Gln 
            20                  25                  30          


Lys Ile Thr Tyr Arg Ile Ser Gly Val Gly Ile Asp Gln Pro Pro Phe 
        35                  40                  45              


Gly Ile Phe Val Val Asp Lys Asn Thr Gly Asp Ile Asn Ile Thr Ala 
    50                  55                  60                  


Ile Val Asp Arg Glu Glu Thr Pro Ser Phe Leu Ile Thr Cys Arg Ala 
65                  70                  75                  80  


Leu Asn Ala Gln Gly Leu Asp Val Glu Lys Pro Leu Ile Leu Thr Val 
                85                  90                  95      


Lys Ile Leu Asp Ile Asn Asp Asn Pro Pro Val Phe Ser Gln Gln Ile 
            100                 105                 110         


Phe Met Gly Glu Ile Glu Glu Asn Ser Ala Ser Asn Ser Leu Val Met 
        115                 120                 125             


Ile Leu Asn Ala Thr Asp Ala Asp Glu Pro Asn His Leu Asn Ser Lys 
    130                 135                 140                 


Ile Ala Phe Lys Ile Val Ser Gln Glu Pro Ala Gly Thr Pro Met Phe 
145                 150                 155                 160 


Leu Leu Ser Arg Asn Thr Gly Glu Val Arg Thr Leu Thr Asn Ser Leu 
                165                 170                 175     


Asp Arg Glu Gln Ala Ser Ser Tyr Arg Leu Val Val Ser Gly Ala Asp 
            180                 185                 190         


Lys Asp Gly Glu Gly Leu Ser Thr Gln Cys Glu Cys Asn Ile Lys Val 
        195                 200                 205             


Lys Asp Val Asn Asp Asn Phe Pro Met Phe Arg Asp Ser Gln Tyr Ser 
    210                 215                 220                 


Ala Arg Ile Glu Glu Asn Ile Leu Ser Ser Glu Leu Leu Arg Phe Gln 
225                 230                 235                 240 


Val Thr Asp Leu Asp Glu Glu Tyr Thr Asp Asn Trp Leu Ala Val Tyr 
                245                 250                 255     


Phe Phe Thr Ser Gly Asn Glu Gly Asn Trp Phe Glu Ile Gln Thr Asp 
            260                 265                 270         


Pro Arg Thr Asn Glu Gly Ile Leu Lys Val Val Lys Ala Leu Asp Tyr 
        275                 280                 285             


Glu Gln Leu Gln Ser Val Lys Leu Ser Ile Ala Val Lys Asn Lys Ala 
    290                 295                 300                 


Glu Phe His Gln Ser Val Ile Ser Arg Tyr Arg Val Gln Ser Thr Pro 
305                 310                 315                 320 


Val Thr Ile Gln Val Ile Asn Val Arg Glu Gly Ile Ala Phe Arg Pro 
                325                 330                 335     


Ala Ser Lys Thr Phe Thr Val Gln Lys Gly Ile Ser Ser Lys Lys Leu 
            340                 345                 350         


Val Asp Tyr Ile Leu Gly Thr Tyr Gln Ala Ile Asp Glu Asp Thr Asn 
        355                 360                 365             


Lys Ala Ala Ser Asn Val Lys Tyr Val Met Gly Arg Asn Asp Gly Gly 
    370                 375                 380                 


Tyr Leu Met Ile Asp Ser Lys Thr Ala Glu Ile Lys Phe Val Lys Asn 
385                 390                 395                 400 


Met Asn Arg Asp Ser Thr Phe Ile Val Asn Lys Thr Ile Thr Ala Glu 
                405                 410                 415     


Val Leu Ala Ile Asp Glu Tyr Thr Gly Lys Thr Ser Thr Gly Thr Val 
            420                 425                 430         


Tyr Val Arg Val Pro Asp Phe Asn Asp Asn Cys Pro Thr Ala Val Leu 
        435                 440                 445             


Glu Lys Asp Ala Val Cys Ser Ser Ser Pro Ser Val Val Val Ser Ala 
    450                 455                 460                 


Arg Thr Leu Asn Asn Arg Tyr Thr Gly Pro Tyr Thr Phe Ala Leu Glu 
465                 470                 475                 480 


Asp Gln Pro Val Lys Leu Pro Ala Val Trp Ser Ile Thr Thr Leu Asn 
                485                 490                 495     


Ala Thr Ser Ala Leu Leu Arg Ala Gln Glu Gln Ile Pro Pro Gly Val 
            500                 505                 510         


Tyr His Ile Ser Leu Val Leu Thr Asp Ser Gln Asn Asn Arg Cys Glu 
        515                 520                 525             


Met Pro Arg Ser Leu Thr Leu Glu Val Cys Gln Cys Asp Asn Arg Gly 
    530                 535                 540                 


Ile Cys Gly Thr Ser Tyr Pro Thr Thr Ser Pro Gly Thr Arg Tyr Gly 
545                 550                 555                 560 


Arg Pro His Ser Gly Arg 
                565     


<210>  363
<211>  582
<212>  PRT
<213>  Homo Sapiens

<400>  363

Glu Trp Ile Lys Phe Ala Ala Ala Cys Arg Glu Gly Glu Asp Asn Ser 
1               5                   10                  15      


Lys Arg Asn Pro Ile Ala Lys Ile Arg Ser Asp Cys Glu Ser Asn Gln 
            20                  25                  30          


Lys Ile Thr Tyr Arg Ile Ser Gly Val Gly Ile Asp Arg Pro Pro Tyr 
        35                  40                  45              


Gly Val Phe Thr Ile Asn Pro Arg Thr Gly Glu Ile Asn Ile Thr Ser 
    50                  55                  60                  


Val Val Asp Arg Glu Ile Thr Pro Leu Phe Leu Ile Tyr Cys Arg Ala 
65                  70                  75                  80  


Leu Asn Ser Arg Gly Glu Asp Leu Glu Arg Pro Leu Glu Leu Arg Val 
                85                  90                  95      


Lys Val Met Asp Ile Asn Asp Asn Ala Pro Val Phe Ser Gln Ser Val 
            100                 105                 110         


Tyr Thr Ala Ser Ile Glu Glu Asn Ser Asp Ala Asn Thr Leu Val Val 
        115                 120                 125             


Lys Leu Cys Ala Thr Asp Ala Asp Glu Glu Asn His Leu Asn Ser Lys 
    130                 135                 140                 


Ile Ala Tyr Lys Ile Val Ser Gln Glu Pro Ser Gly Ala Pro Met Phe 
145                 150                 155                 160 


Ile Leu Asn Arg Tyr Thr Gly Glu Val Cys Thr Met Ser Ser Phe Leu 
                165                 170                 175     


Asp Arg Glu Gln His Ser Met Tyr Asn Leu Val Val Arg Gly Ser Asp 
            180                 185                 190         


Arg Asp Gly Ala Ala Asp Gly Leu Ser Ser Glu Cys Asp Cys Arg Ile 
        195                 200                 205             


Lys Val Leu Asp Val Asn Asp Asn Phe Pro Thr Leu Glu Lys Thr Ser 
    210                 215                 220                 


Tyr Ser Ala Ser Ile Glu Glu Asn Cys Leu Ser Ser Glu Leu Ile Arg 
225                 230                 235                 240 


Leu Gln Ala Ile Asp Leu Asp Glu Glu Gly Thr Asp Asn Trp Leu Ala 
                245                 250                 255     


Gln Tyr Leu Ile Leu Ser Gly Asn Asp Gly Asn Trp Phe Asp Ile Gln 
            260                 265                 270         


Thr Asp Pro Gln Thr Asn Glu Gly Ile Leu Lys Val Val Lys Met Leu 
        275                 280                 285             


Asp Tyr Glu Gln Ala Pro Asn Ile Gln Leu Ser Ile Gly Val Lys Asn 
    290                 295                 300                 


Gln Ala Asp Phe His Tyr Ser Val Ala Ser Gln Phe Gln Met His Pro 
305                 310                 315                 320 


Thr Pro Val Arg Ile Gln Val Val Asp Val Arg Glu Gly Pro Ala Phe 
                325                 330                 335     


His Pro Ser Thr Met Ala Phe Ser Val Arg Glu Gly Ile Lys Gly Ser 
            340                 345                 350         


Ser Leu Leu Asn Tyr Val Leu Gly Thr Tyr Thr Ala Ile Asp Leu Asp 
        355                 360                 365             


Thr Gly Asn Pro Ala Thr Asp Val Arg Tyr Ile Ile Gly His Asp Ala 
    370                 375                 380                 


Gly Ser Trp Leu Lys Ile Asp Ser Arg Thr Gly Glu Ile Gln Phe Ser 
385                 390                 395                 400 


Arg Glu Phe Asp Lys Lys Ser Lys Tyr Ile Ile Asn Gly Ile Tyr Thr 
                405                 410                 415     


Ala Glu Ile Leu Ala Ile Asp Asp Gly Ser Gly Lys Thr Ala Thr Gly 
            420                 425                 430         


Thr Ile Cys Ile Glu Val Pro Asp Ile Asn Asp Tyr Cys Pro Asn Ile 
        435                 440                 445             


Phe Pro Glu Arg Arg Thr Ile Cys Ile Asp Ser Pro Ser Val Leu Ile 
    450                 455                 460                 


Ser Val Asn Glu His Ser Tyr Gly Ser Pro Phe Thr Phe Cys Val Val 
465                 470                 475                 480 


Asp Glu Pro Pro Gly Ile Ala Asp Met Trp Asp Val Arg Ser Thr Asn 
                485                 490                 495     


Ala Thr Ser Ala Ile Leu Thr Ala Lys Gln Val Leu Ser Pro Gly Phe 
            500                 505                 510         


Tyr Glu Ile Pro Ile Leu Val Lys Asp Ser Tyr Asn Arg Ala Cys Glu 
        515                 520                 525             


Leu Ala Gln Met Val Gln Leu Tyr Ala Cys Asp Cys Asp Asp Asn His 
    530                 535                 540                 


Met Cys Leu Asp Ser Gly Ala Ala Gly Ile Tyr Thr Glu Asp Ile Thr 
545                 550                 555                 560 


Gly Asp Thr Tyr Gly Pro Val Thr Glu Asp Gln Ala Gly Val Ser Asn 
                565                 570                 575     


Val Gly Leu Gly Pro Ala 
            580         


<210>  364
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  364

Arg Lys Gly Pro Pro Ala Ala Leu Thr Leu Pro Arg Val Gln Cys Arg 
1               5                   10                  15      


Ala Ser Arg Tyr Pro Ile Ala Val Asp Cys Ser Trp Thr Leu Pro Pro 
            20                  25                  30          


Ala Pro Asn Ser Thr Ser Pro Val Ser Phe Ile Ala Thr Tyr Arg Leu 
        35                  40                  45              


Gly Met Ala Ala Arg Gly His Ser Trp Pro Cys Leu Gln Gln Thr Pro 
    50                  55                  60                  


Thr Ser Thr Ser Cys Thr Ile Thr Asp Val Gln Leu Phe Ser Met Ala 
65                  70                  75                  80  


Pro Tyr Val Leu Asn Val Thr Ala Val His Pro Trp Gly Ser Ser Ser 
                85                  90                  95      


Ser Phe Val Pro Phe Ile Thr Glu His Ile Ile Lys Pro Asp Pro Pro 
            100                 105                 110         


Glu Gly Val Arg Leu Ser Pro Leu Ala Glu Arg Gln Leu Gln Val Gln 
        115                 120                 125             


Trp Glu Pro Pro Gly Ser Trp Pro Phe Pro Glu Ile Phe Ser Leu Lys 
    130                 135                 140                 


Tyr Trp Ile Arg Tyr Lys Arg Gln Gly Ala Ala Arg Phe His Arg Val 
145                 150                 155                 160 


Gly Pro Ile Glu Ala Thr Ser Phe Ile Leu Arg Ala Val Arg Pro Arg 
                165                 170                 175     


Ala Arg Tyr Tyr Val Gln Val Ala Ala Gln Asp Leu Thr Asp Tyr Gly 
            180                 185                 190         


Glu Leu Ser Asp Trp Ser Leu Pro Ala Thr Ala Thr Met Ser Leu Gly 
        195                 200                 205             


Lys 
    


<210>  365
<211>  623
<212>  PRT
<213>  Homo Sapiens

<400>  365

Lys Asn Glu Glu Ile Pro Arg Lys Gln Arg Arg Lys Ile Tyr His Arg 
1               5                   10                  15      


Arg Leu Arg Lys Ser Ser Thr Ser His Lys His Arg Ser Asn Arg Gln 
            20                  25                  30          


Leu Gly Ile Pro Gln Thr Thr Val Phe Thr Pro Val Ala Arg Leu Pro 
        35                  40                  45              


Ile Val Asn Phe Asp Tyr Ser Met Glu Glu Lys Phe Glu Ser Phe Ser 
    50                  55                  60                  


Ser Phe Pro Gly Val Glu Ser Ser Tyr Asn Val Leu Pro Gly Lys Lys 
65                  70                  75                  80  


Gly His Cys Leu Val Lys Gly Ile Thr Met Tyr Asn Lys Ala Val Trp 
                85                  90                  95      


Ser Pro Glu Pro Cys Thr Thr Cys Leu Cys Ser Asp Gly Arg Val Leu 
            100                 105                 110         


Cys Asp Glu Thr Met Cys His Pro Gln Arg Cys Pro Gln Thr Val Ile 
        115                 120                 125             


Pro Glu Gly Glu Cys Cys Pro Val Cys Ser Ala Thr Glu Gln Arg Glu 
    130                 135                 140                 


Pro Thr Asn Leu Leu His Lys Gln Leu Pro Pro Pro Gln Val Gly Met 
145                 150                 155                 160 


Asp Arg Ile Val Arg Lys Glu Ala Leu Gln Ser Glu Glu Asp Glu Glu 
                165                 170                 175     


Val Lys Glu Glu Asp Pro Glu Gln Lys Arg Glu Thr Pro Glu Ser Arg 
            180                 185                 190         


Asn Gln Gly Gln Leu Tyr Ser Glu Gly Asp Ser Arg Gly Gly Asp Arg 
        195                 200                 205             


Lys Gln Arg Pro Gly Glu Glu Arg Arg Leu Ala His Gln Gln Gln Arg 
    210                 215                 220                 


Gln Gly Arg Glu Glu Glu Glu Asp Glu Glu Glu Glu Gly Glu Glu Gly 
225                 230                 235                 240 


Glu Glu Asp Glu Glu Asp Glu Glu Asp Pro Val Arg Gly Asp Met Phe 
                245                 250                 255     


Arg Met Pro Ser Arg Ser Pro Leu Pro Ala Pro Pro Arg Gly Thr Leu 
            260                 265                 270         


Arg Leu Pro Ser Gly Cys Ser Leu Ser Tyr Arg Thr Ile Ser Cys Ile 
        275                 280                 285             


Asn Ala Met Leu Thr Gln Ile Pro Pro Leu Thr Ala Pro Gln Ile Thr 
    290                 295                 300                 


Ser Leu Glu Leu Thr Gly Asn Ser Ile Ala Ser Ile Pro Asp Glu Ala 
305                 310                 315                 320 


Phe Asn Gly Leu Pro Asn Leu Glu Arg Leu Asp Leu Ser Lys Asn Asn 
                325                 330                 335     


Ile Thr Ser Ser Gly Ile Gly Pro Lys Ala Phe Lys Leu Leu Lys Lys 
            340                 345                 350         


Leu Met Arg Leu Asn Met Asp Gly Asn Asn Leu Ile Gln Ile Pro Ser 
        355                 360                 365             


Gln Leu Pro Ser Thr Leu Glu Glu Leu Lys Val Asn Glu Asn Asn Leu 
    370                 375                 380                 


Gln Ala Ile Asp Glu Glu Ser Leu Ser Asp Leu Asn Gln Leu Val Thr 
385                 390                 395                 400 


Leu Glu Leu Glu Gly Asn Asn Leu Ser Glu Ala Asn Val Asn Pro Leu 
                405                 410                 415     


Ala Phe Lys Pro Leu Lys Ser Leu Ala Tyr Leu Arg Leu Gly Lys Asn 
            420                 425                 430         


Lys Phe Arg Ile Ile Pro Gln Gly Leu Pro Gly Ser Ile Glu Glu Leu 
        435                 440                 445             


Tyr Leu Glu Asn Asn Gln Ile Glu Glu Ile Thr Glu Ile Cys Phe Asn 
    450                 455                 460                 


His Thr Arg Lys Ile Asn Val Ile Val Leu Arg Tyr Asn Lys Ile Glu 
465                 470                 475                 480 


Glu Asn Arg Ile Ala Pro Leu Ala Trp Ile Asn Gln Glu Asn Leu Glu 
                485                 490                 495     


Ser Ile Asp Leu Ser Tyr Asn Lys Leu Tyr His Val Pro Ser Tyr Leu 
            500                 505                 510         


Pro Lys Ser Leu Leu His Leu Val Leu Leu Gly Asn Gln Ile Glu Arg 
        515                 520                 525             


Ile Pro Gly Tyr Val Phe Gly His Met Glu Pro Gly Leu Glu Tyr Leu 
    530                 535                 540                 


Tyr Leu Ser Phe Asn Lys Leu Ala Asp Asp Gly Met Asp Arg Val Ser 
545                 550                 555                 560 


Phe Tyr Gly Ala Tyr His Ser Leu Arg Glu Leu Phe Leu Asp His Asn 
                565                 570                 575     


Asp Leu Lys Ser Ile Pro Pro Gly Ile Gln Glu Met Lys Ala Leu His 
            580                 585                 590         


Phe Leu Arg Leu Asn Asn Asn Lys Ile Arg Cys Val Ser Asp Ala Val 
        595                 600                 605             


Leu Glu Thr Val Thr Asn Arg Ser Asp Val Ala Phe Pro Leu Trp 
    610                 615                 620             


<210>  366
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  366

Ser Lys Ser Asn Glu Gly Ala Asp Gly Pro Val Lys Asn Lys Lys Lys 
1               5                   10                  15      


Gly Lys Lys Ala Gly Pro Pro Gly Pro Asn Gly Pro Pro Gly Pro Pro 
            20                  25                  30          


Gly Pro Pro Gly Pro Gln Gly Pro Pro Gly Ile Pro Gly Ile Pro Gly 
        35                  40                  45              


Ile Pro Gly Thr Thr Val Met Gly Pro Pro Gly Pro Pro Gly Pro Pro 
    50                  55                  60                  


Gly Pro Gln Gly Pro Pro Gly Leu Gln Gly Pro Ser Gly Ala Ala Asp 
65                  70                  75                  80  


Lys Ala Gly Thr Arg Glu Asn Gln Pro Ala Val Val His Leu Gln Gly 
                85                  90                  95      


Gln Gly Ser Ala Ile Gln Val Lys Asn Asp Leu Ser Gly Gly Val Leu 
            100                 105                 110         


Asn Asp Trp Ser Arg Ile Thr Met Asn Pro Lys Val Phe Lys Leu His 
        115                 120                 125             


Pro Arg Ser Gly Glu Leu Glu Val Leu Val Asp Gly Thr Tyr Phe Ile 
    130                 135                 140                 


Tyr Ser Gln Val Glu Val Tyr Tyr Ile Asn Phe Thr Asp Phe Ala Ser 
145                 150                 155                 160 


Tyr Glu Val Val Val Asp Glu Lys Pro Phe Leu Gln Cys Thr Arg Ser 
                165                 170                 175     


Ile Glu Thr Gly Lys Thr Asn Tyr Asn Thr Cys Tyr Thr Ala Gly Val 
            180                 185                 190         


Cys Leu Leu Lys Ala Arg Gln Lys Ile Ala Val Lys Met Val His Ala 
        195                 200                 205             


Asp Ile Ser Ile Asn Met Ser Lys His Thr Thr Phe Phe Gly Ala Ile 
    210                 215                 220                 


Arg Leu Gly Glu Ala Pro Ala Ser 
225                 230         


<210>  367
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  367

Met Asp Cys Gln Glu Asn Glu Tyr Trp Asp Gln Trp Gly Arg Cys Val 
1               5                   10                  15      


Thr Cys Gln Arg Cys Gly Pro Gly Gln Glu Leu Ser Lys Asp Cys Gly 
            20                  25                  30          


Tyr Gly Glu Gly Gly Asp Ala Tyr Cys Thr Ala Cys Pro Pro Arg Arg 
        35                  40                  45              


Tyr Lys Ser Ser Trp Gly His His Arg Cys Gln Ser Cys Ile Thr Cys 
    50                  55                  60                  


Ala Val Ile Asn Arg Val Gln Lys Val Asn Cys Thr Ala Thr Ser Asn 
65                  70                  75                  80  


Ala Val Cys Gly Asp Cys Leu Pro Arg Phe Tyr Arg Lys Thr Arg Ile 
                85                  90                  95      


Gly Gly Leu Gln Asp Gln Glu Cys Ile Pro Cys Thr Lys Gln Thr Pro 
            100                 105                 110         


Thr Ser Glu Val Gln Cys Ala Phe Gln Leu Ser Leu Val Glu Ala Asp 
        115                 120                 125             


Ala Pro Thr Val Pro Pro Gln Glu Ala Thr 
    130                 135             


<210>  368
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  368

Glu Tyr Ser Asn Cys Gly Glu Asn Glu Tyr Tyr Asn Gln Thr Thr Gly 
1               5                   10                  15      


Leu Cys Gln Glu Cys Pro Pro Cys Gly Pro Gly Glu Glu Pro Tyr Leu 
            20                  25                  30          


Ser Cys Gly Tyr Gly Thr Lys Asp Glu Asp Tyr Gly Cys Val Pro Cys 
        35                  40                  45              


Pro Ala Glu Lys Phe Ser Lys Gly Gly Tyr Gln Ile Cys Arg Arg His 
    50                  55                  60                  


Lys Asp Cys Glu Gly Phe Phe Arg Ala Thr Val Leu Thr Pro Gly Asp 
65                  70                  75                  80  


Val Glu Asn Asp Ala Glu Cys Gly Pro Cys Leu Pro Gly Tyr Tyr Met 
                85                  90                  95      


Leu Glu Asn Arg Pro Arg Asn Ile Tyr Gly Met Val Cys Tyr Ser Cys 
            100                 105                 110         


Leu Leu Ala Pro Pro Asn Thr Lys Glu Cys Val Gly Ala Thr Ser Gly 
        115                 120                 125             


Ala Ser Ala Asn Phe Pro Gly Thr Ser Gly Ser Ser Thr Leu Ser Pro 
    130                 135                 140                 


Phe Gln His Ala His Lys Glu Leu Ser Gly Gln Gly His Leu Ala Thr 
145                 150                 155                 160 


Ala 
    


<210>  369
<211>  457
<212>  PRT
<213>  Homo Sapiens

<400>  369

Asp Ile Cys Asp Pro Asn Pro Cys Glu Asn Gly Gly Ile Cys Leu Pro 
1               5                   10                  15      


Gly Leu Ala Asp Gly Ser Phe Ser Cys Glu Cys Pro Asp Gly Phe Thr 
            20                  25                  30          


Asp Pro Asn Cys Ser Ser Val Val Glu Val Ala Ser Asp Glu Glu Glu 
        35                  40                  45              


Pro Thr Ser Ala Gly Pro Cys Thr Pro Asn Pro Cys His Asn Gly Gly 
    50                  55                  60                  


Thr Cys Glu Ile Ser Glu Ala Tyr Arg Gly Asp Thr Phe Ile Gly Tyr 
65                  70                  75                  80  


Val Cys Lys Cys Pro Arg Gly Phe Asn Gly Ile His Cys Gln His Asn 
                85                  90                  95      


Ile Asn Glu Cys Glu Val Glu Pro Cys Lys Asn Gly Gly Ile Cys Thr 
            100                 105                 110         


Asp Leu Val Ala Asn Tyr Ser Cys Glu Cys Pro Gly Glu Phe Met Gly 
        115                 120                 125             


Arg Asn Cys Gln Tyr Lys Cys Ser Gly Pro Leu Gly Ile Glu Gly Gly 
    130                 135                 140                 


Ile Ile Ser Asn Gln Gln Ile Thr Ala Ser Ser Thr His Arg Ala Leu 
145                 150                 155                 160 


Phe Gly Leu Gln Lys Trp Tyr Pro Tyr Tyr Ala Arg Leu Asn Lys Lys 
                165                 170                 175     


Gly Leu Ile Asn Ala Trp Thr Ala Ala Glu Asn Asp Arg Trp Pro Trp 
            180                 185                 190         


Ile Gln Ile Asn Leu Gln Arg Lys Met Arg Val Thr Gly Val Ile Thr 
        195                 200                 205             


Gln Gly Ala Lys Arg Ile Gly Ser Pro Glu Tyr Ile Lys Ser Tyr Lys 
    210                 215                 220                 


Ile Ala Tyr Ser Asn Asp Gly Lys Thr Trp Ala Met Tyr Lys Val Lys 
225                 230                 235                 240 


Gly Thr Asn Glu Asp Met Val Phe Arg Gly Asn Ile Asp Asn Asn Thr 
                245                 250                 255     


Pro Tyr Ala Asn Ser Phe Thr Pro Pro Ile Lys Ala Gln Tyr Val Arg 
            260                 265                 270         


Leu Tyr Pro Gln Val Cys Arg Arg His Cys Thr Leu Arg Met Glu Leu 
        275                 280                 285             


Leu Gly Cys Glu Leu Ser Gly Cys Ser Glu Pro Leu Gly Met Lys Ser 
    290                 295                 300                 


Gly His Ile Gln Asp Tyr Gln Ile Thr Ala Ser Ser Ile Phe Arg Thr 
305                 310                 315                 320 


Leu Asn Met Asp Met Phe Thr Trp Glu Pro Arg Lys Ala Arg Leu Asp 
                325                 330                 335     


Lys Gln Gly Lys Val Asn Ala Trp Thr Ser Gly His Asn Asp Gln Ser 
            340                 345                 350         


Gln Trp Leu Gln Val Asp Leu Leu Val Pro Thr Lys Val Thr Gly Ile 
        355                 360                 365             


Ile Thr Gln Gly Ala Lys Asp Phe Gly His Val Gln Phe Val Gly Ser 
    370                 375                 380                 


Tyr Lys Leu Ala Tyr Ser Asn Asp Gly Glu His Trp Thr Val Tyr Gln 
385                 390                 395                 400 


Asp Glu Lys Gln Arg Lys Asp Lys Val Phe Gln Gly Asn Phe Asp Asn 
                405                 410                 415     


Asp Thr His Arg Lys Asn Val Ile Asp Pro Pro Ile Tyr Ala Arg His 
            420                 425                 430         


Ile Arg Ile Leu Pro Trp Ser Trp Tyr Gly Arg Ile Thr Leu Arg Ser 
        435                 440                 445             


Glu Leu Leu Gly Cys Thr Glu Glu Glu 
    450                 455         


<210>  370
<211>  476
<212>  PRT
<213>  Homo Sapiens

<400>  370

Gln Asp Thr Glu Glu Thr Ile Thr Tyr Thr Gln Cys Thr Asp Gly Tyr 
1               5                   10                  15      


Glu Trp Asp Pro Val Arg Gln Gln Cys Lys Asp Ile Asp Glu Cys Asp 
            20                  25                  30          


Ile Val Pro Asp Ala Cys Lys Gly Gly Met Lys Cys Val Asn His Tyr 
        35                  40                  45              


Gly Gly Tyr Leu Cys Leu Pro Lys Thr Ala Gln Ile Ile Val Asn Asn 
    50                  55                  60                  


Glu Gln Pro Gln Gln Glu Thr Gln Pro Ala Glu Gly Thr Ser Gly Ala 
65                  70                  75                  80  


Thr Thr Gly Val Val Ala Ala Ser Ser Met Ala Thr Ser Gly Val Leu 
                85                  90                  95      


Pro Gly Gly Gly Phe Val Ala Ser Ala Ala Ala Val Ala Gly Pro Glu 
            100                 105                 110         


Met Gln Thr Gly Arg Asn Asn Phe Val Ile Arg Arg Asn Pro Ala Asp 
        115                 120                 125             


Pro Gln Arg Ile Pro Ser Asn Pro Ser His Arg Ile Gln Cys Ala Ala 
    130                 135                 140                 


Gly Tyr Glu Gln Ser Glu His Asn Val Cys Gln Asp Ile Asp Glu Cys 
145                 150                 155                 160 


Thr Ala Gly Thr His Asn Cys Arg Ala Asp Gln Val Cys Ile Asn Leu 
                165                 170                 175     


Arg Gly Ser Phe Ala Cys Gln Cys Pro Pro Gly Tyr Gln Lys Arg Gly 
            180                 185                 190         


Glu Gln Cys Val Asp Ile Asp Glu Cys Thr Ile Pro Pro Tyr Cys His 
        195                 200                 205             


Gln Arg Cys Val Asn Thr Pro Gly Ser Phe Tyr Cys Gln Cys Ser Pro 
    210                 215                 220                 


Gly Phe Gln Leu Ala Ala Asn Asn Tyr Thr Cys Val Asp Ile Asn Glu 
225                 230                 235                 240 


Cys Asp Ala Ser Asn Gln Cys Ala Gln Gln Cys Tyr Asn Ile Leu Gly 
                245                 250                 255     


Ser Phe Ile Cys Gln Cys Asn Gln Gly Tyr Glu Leu Ser Ser Asp Arg 
            260                 265                 270         


Leu Asn Cys Glu Asp Ile Asp Glu Cys Arg Thr Ser Ser Tyr Leu Cys 
        275                 280                 285             


Gln Tyr Gln Cys Val Asn Glu Pro Gly Lys Phe Ser Cys Met Cys Pro 
    290                 295                 300                 


Gln Gly Tyr Gln Val Val Arg Ser Arg Thr Cys Gln Asp Ile Asn Glu 
305                 310                 315                 320 


Cys Glu Thr Thr Asn Glu Cys Arg Glu Asp Glu Met Cys Trp Asn Tyr 
                325                 330                 335     


His Gly Gly Phe Arg Cys Tyr Pro Arg Asn Pro Cys Gln Asp Pro Tyr 
            340                 345                 350         


Ile Leu Thr Pro Glu Asn Arg Cys Val Cys Pro Val Ser Asn Ala Met 
        355                 360                 365             


Cys Arg Glu Leu Pro Gln Ser Ile Val Tyr Lys Tyr Met Ser Ile Arg 
    370                 375                 380                 


Ser Asp Arg Ser Val Pro Ser Asp Ile Phe Gln Ile Gln Ala Thr Thr 
385                 390                 395                 400 


Ile Tyr Ala Asn Thr Ile Asn Thr Phe Arg Ile Lys Ser Gly Asn Glu 
                405                 410                 415     


Asn Gly Glu Phe Tyr Leu Arg Gln Thr Ser Pro Val Ser Ala Met Leu 
            420                 425                 430         


Val Leu Val Lys Ser Leu Ser Gly Pro Arg Glu His Ile Val Asp Leu 
        435                 440                 445             


Glu Met Leu Thr Val Ser Ser Ile Gly Thr Phe Arg Thr Ser Ser Val 
    450                 455                 460                 


Leu Arg Leu Thr Ile Ile Val Gly Pro Phe Ser Phe 
465                 470                 475     


<210>  371
<211>  418
<212>  PRT
<213>  Homo Sapiens

<400>  371

Ser Pro Gln Asp Ser Glu Glu Pro Asp Ser Tyr Thr Glu Cys Thr Asp 
1               5                   10                  15      


Gly Tyr Glu Trp Asp Pro Asp Ser Gln His Cys Arg Asp Val Asn Glu 
            20                  25                  30          


Cys Leu Thr Ile Pro Glu Ala Cys Lys Gly Glu Met Lys Cys Ile Asn 
        35                  40                  45              


His Tyr Gly Gly Tyr Leu Cys Leu Pro Arg Ser Ala Ala Val Ile Asn 
    50                  55                  60                  


Asp Leu His Gly Glu Gly Pro Pro Pro Pro Val Pro Pro Ala Gln His 
65                  70                  75                  80  


Pro Asn Pro Cys Pro Pro Gly Tyr Glu Pro Asp Asp Gln Asp Ser Cys 
                85                  90                  95      


Val Asp Val Asp Glu Cys Ala Gln Ala Leu His Asp Cys Arg Pro Ser 
            100                 105                 110         


Gln Asp Cys His Asn Leu Pro Gly Ser Tyr Gln Cys Thr Cys Pro Asp 
        115                 120                 125             


Gly Tyr Arg Lys Ile Gly Pro Glu Cys Val Asp Ile Asp Glu Cys Arg 
    130                 135                 140                 


Tyr Arg Tyr Cys Gln His Arg Cys Val Asn Leu Pro Gly Ser Phe Arg 
145                 150                 155                 160 


Cys Gln Cys Glu Pro Gly Phe Gln Leu Gly Pro Asn Asn Arg Ser Cys 
                165                 170                 175     


Val Asp Val Asn Glu Cys Asp Met Gly Ala Pro Cys Glu Gln Arg Cys 
            180                 185                 190         


Phe Asn Ser Tyr Gly Thr Phe Leu Cys Arg Cys His Gln Gly Tyr Glu 
        195                 200                 205             


Leu His Arg Asp Gly Phe Ser Cys Ser Asp Ile Asp Glu Cys Ser Tyr 
    210                 215                 220                 


Ser Ser Tyr Leu Cys Gln Tyr Arg Cys Val Asn Glu Pro Gly Arg Phe 
225                 230                 235                 240 


Ser Cys His Cys Pro Gln Gly Tyr Gln Leu Leu Ala Thr Arg Leu Cys 
                245                 250                 255     


Gln Asp Ile Asp Glu Cys Glu Ser Gly Ala His Gln Cys Ser Glu Ala 
            260                 265                 270         


Gln Thr Cys Val Asn Phe His Gly Gly Tyr Arg Cys Val Asp Thr Asn 
        275                 280                 285             


Arg Cys Val Glu Pro Tyr Ile Gln Val Ser Glu Asn Arg Cys Leu Cys 
    290                 295                 300                 


Pro Ala Ser Asn Pro Leu Cys Arg Glu Gln Pro Ser Ser Ile Val His 
305                 310                 315                 320 


Arg Tyr Met Thr Ile Thr Ser Glu Arg Ser Val Pro Ala Asp Val Phe 
                325                 330                 335     


Gln Ile Gln Ala Thr Ser Val Tyr Pro Gly Ala Tyr Asn Ala Phe Gln 
            340                 345                 350         


Ile Arg Ala Gly Asn Ser Gln Gly Asp Phe Tyr Ile Arg Gln Ile Asn 
        355                 360                 365             


Asn Val Ser Ala Met Leu Val Leu Ala Arg Pro Val Thr Gly Pro Arg 
    370                 375                 380                 


Glu Tyr Val Leu Asp Leu Glu Met Val Thr Met Asn Ser Leu Met Ser 
385                 390                 395                 400 


Tyr Arg Ala Ser Ser Val Leu Arg Leu Thr Val Phe Val Gly Ala Tyr 
                405                 410                 415     


Thr Phe 
        


<210>  372
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  372

Asp Arg His Thr Val Phe Trp Asn Ser Ser Asn Pro Lys Phe Arg Asn 
1               5                   10                  15      


Glu Asp Tyr Thr Ile His Val Gln Leu Asn Asp Tyr Val Asp Ile Ile 
            20                  25                  30          


Cys Pro His Tyr Glu Asp His Ser Val Ala Asp Ala Ala Met Glu Gln 
        35                  40                  45              


Tyr Ile Leu Tyr Leu Val Glu His Glu Glu Tyr Gln Leu Cys Gln Pro 
    50                  55                  60                  


Gln Ser Lys Asp Gln Val Arg Trp Gln Cys Asn Arg Pro Ser Ala Lys 
65                  70                  75                  80  


His Gly Pro Glu Lys Leu Ser Glu Lys Phe Gln Arg Phe Thr Pro Phe 
                85                  90                  95      


Thr Leu Gly Lys Glu Phe Lys Glu Gly His Ser Tyr Tyr Tyr Ile Ser 
            100                 105                 110         


Lys Pro Ile His Gln His Glu Asp Arg Cys Leu Arg Leu Lys Val Thr 
        115                 120                 125             


Val Ser Gly Lys Ile Thr His Ser Pro Gln Ala His Val Asn Pro Gln 
    130                 135                 140                 


Glu Lys Arg Leu Ala Ala Asp Asp Pro Glu Val Arg Val Leu His Ser 
145                 150                 155                 160 


Ile Ala His Ser 
                


<210>  373
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  373

Arg Ala Glu Asp Ala Ala Arg Ala Asn Ser Asp Arg Tyr Ala Val Tyr 
1               5                   10                  15      


Trp Asn Arg Ser Asn Pro Arg Phe His Ala Gly Ala Gly Asp Asp Gly 
            20                  25                  30          


Gly Gly Tyr Thr Val Glu Val Ser Ile Asn Asp Tyr Leu Asp Ile Tyr 
        35                  40                  45              


Cys Pro His Tyr Gly Ala Pro Leu Pro Pro Ala Glu Arg Met Glu His 
    50                  55                  60                  


Tyr Val Leu Tyr Met Val Asn Gly Glu Gly His Ala Ser Cys Asp His 
65                  70                  75                  80  


Arg Gln Arg Gly Phe Lys Arg Trp Glu Cys Asn Arg Pro Ala Ala Pro 
                85                  90                  95      


Gly Gly Pro Leu Lys Phe Ser Glu Lys Phe Gln Leu Phe Thr Pro Phe 
            100                 105                 110         


Ser Leu Gly Phe Glu Phe Arg Pro Gly His Glu Tyr Tyr Tyr Ile Ser 
        115                 120                 125             


Ala Thr Pro Pro Asn Ala Val Asp Arg Pro Cys Leu Arg Leu Lys Val 
    130                 135                 140                 


Tyr Val Arg Pro Thr Asn Glu Thr Leu Tyr Glu Ala Pro Glu Pro Ile 
145                 150                 155                 160 


Phe Thr Ser Asn 
                


<210>  374
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  374

Gln Gly Pro Gly Gly Ala Leu Gly Asn Arg His Ala Val Tyr Trp Asn 
1               5                   10                  15      


Ser Ser Asn Gln His Leu Arg Arg Glu Gly Tyr Thr Val Gln Val Asn 
            20                  25                  30          


Val Asn Asp Tyr Leu Asp Ile Tyr Cys Pro His Tyr Asn Ser Ser Gly 
        35                  40                  45              


Val Gly Pro Gly Ala Gly Pro Gly Pro Gly Gly Gly Ala Glu Gln Tyr 
    50                  55                  60                  


Val Leu Tyr Met Val Ser Arg Asn Gly Tyr Arg Thr Cys Asn Ala Ser 
65                  70                  75                  80  


Gln Gly Phe Lys Arg Trp Glu Cys Asn Arg Pro His Ala Pro His Ser 
                85                  90                  95      


Pro Ile Lys Phe Ser Glu Lys Phe Gln Arg Tyr Ser Ala Phe Ser Leu 
            100                 105                 110         


Gly Tyr Glu Phe His Ala Gly His Glu Tyr Tyr Tyr Ile Ser Thr Pro 
        115                 120                 125             


Thr His Asn Leu His Trp Lys Cys Leu Arg Met Lys Val Phe Val Cys 
    130                 135                 140                 


Cys Ala Ser Thr Ser His Ser Gly Glu Lys Pro Val Pro Thr Leu Pro 
145                 150                 155                 160 


Gln Phe Thr Met Gly Pro Asn Val Lys Ile Asn Val Leu Glu Asp Phe 
                165                 170                 175     


Glu Gly Glu Asn Pro Gln Val Pro Lys Leu Glu Lys Ser Ile Ser Gly 
            180                 185                 190         


<210>  375
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  375

Gln Asp Pro Gly Ser Lys Ala Val Ala Asp Arg Tyr Ala Val Tyr Trp 
1               5                   10                  15      


Asn Ser Ser Asn Pro Arg Phe Gln Arg Gly Asp Tyr His Ile Asp Val 
            20                  25                  30          


Cys Ile Asn Asp Tyr Leu Asp Val Phe Cys Pro His Tyr Glu Asp Ser 
        35                  40                  45              


Val Pro Glu Asp Lys Thr Glu Arg Tyr Val Leu Tyr Met Val Asn Phe 
    50                  55                  60                  


Asp Gly Tyr Ser Ala Cys Asp His Thr Ser Lys Gly Phe Lys Arg Trp 
65                  70                  75                  80  


Glu Cys Asn Arg Pro His Ser Pro Asn Gly Pro Leu Lys Phe Ser Glu 
                85                  90                  95      


Lys Phe Gln Leu Phe Thr Pro Phe Ser Leu Gly Phe Glu Phe Arg Pro 
            100                 105                 110         


Gly Arg Glu Tyr Phe Tyr Ile Ser Ser Ala Ile Pro Asp Asn Gly Arg 
        115                 120                 125             


Arg Ser Cys Leu Lys Leu Lys Val Phe Val Arg Pro Thr Asn Ser Cys 
    130                 135                 140                 


Met Lys Thr Ile Gly Val His Asp Arg Val Phe Asp Val Asn Asp Lys 
145                 150                 155                 160 


Val Glu Asn Ser Leu Glu Pro Ala Asp Asp Thr Val His Glu Ser Ala 
                165                 170                 175     


Glu Pro Ser Arg Gly Glu Asn 
            180             


<210>  376
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  376

Leu Ala Lys Asn Leu Glu Pro Val Ser Trp Ser Ser Leu Asn Pro Lys 
1               5                   10                  15      


Phe Leu Ser Gly Lys Gly Leu Val Ile Tyr Pro Lys Ile Gly Asp Lys 
            20                  25                  30          


Leu Asp Ile Ile Cys Pro Arg Ala Glu Ala Gly Arg Pro Tyr Glu Tyr 
        35                  40                  45              


Tyr Lys Leu Tyr Leu Val Arg Pro Glu Gln Ala Ala Ala Cys Ser Thr 
    50                  55                  60                  


Val Leu Asp Pro Asn Val Leu Val Thr Cys Asn Arg Pro Glu Gln Glu 
65                  70                  75                  80  


Ile Arg Phe Thr Ile Lys Phe Gln Glu Phe Ser Pro Asn Tyr Met Gly 
                85                  90                  95      


Leu Glu Phe Lys Lys His His Asp Tyr Tyr Ile Thr Ser Thr Ser Asn 
            100                 105                 110         


Gly Ser Leu Glu Gly Leu Glu Asn Arg Glu Gly Gly Val Cys Arg Thr 
        115                 120                 125             


Arg Thr Met Lys Ile Ile Met Lys Val Gly Gln Asp Pro Asn Ala Val 
    130                 135                 140                 


Thr Pro Glu Gln Leu Thr Thr Ser Arg Pro Ser Lys Glu Ala Asp Asn 
145                 150                 155                 160 


Thr Val Lys Met Ala Thr Gln Ala Pro Gly Ser Arg Gly Ser Leu Gly 
                165                 170                 175     


Asp Ser Asp Gly Lys His Glu Thr Val Asn Gln Glu Glu Lys Ser Gly 
            180                 185                 190         


Pro Gly Ala Ser Gly Gly Ser Ser Gly Asp Pro Asp Gly Phe Phe Asn 
        195                 200                 205             


Ser Lys 
    210 


<210>  377
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  377

Ile Val Leu Glu Pro Ile Tyr Trp Asn Ser Ser Asn Ser Lys Phe Leu 
1               5                   10                  15      


Pro Gly Gln Gly Leu Val Leu Tyr Pro Gln Ile Gly Asp Lys Leu Asp 
            20                  25                  30          


Ile Ile Cys Pro Lys Val Asp Ser Lys Thr Val Gly Gln Tyr Glu Tyr 
        35                  40                  45              


Tyr Lys Val Tyr Met Val Asp Lys Asp Gln Ala Asp Arg Cys Thr Ile 
    50                  55                  60                  


Lys Lys Glu Asn Thr Pro Leu Leu Asn Cys Ala Lys Pro Asp Gln Asp 
65                  70                  75                  80  


Ile Lys Phe Thr Ile Lys Phe Gln Glu Phe Ser Pro Asn Leu Trp Gly 
                85                  90                  95      


Leu Glu Phe Gln Lys Asn Lys Asp Tyr Tyr Ile Ile Ser Thr Ser Asn 
            100                 105                 110         


Gly Ser Leu Glu Gly Leu Asp Asn Gln Glu Gly Gly Val Cys Gln Thr 
        115                 120                 125             


Arg Ala Met Lys Ile Leu Met Lys Val Gly Gln Asp Ala Ser Ser Ala 
    130                 135                 140                 


Gly Ser Thr Arg Asn Lys Asp Pro Thr Arg Arg Pro Glu Leu Glu Ala 
145                 150                 155                 160 


Gly Thr Asn Gly Arg Ser Ser Thr Thr Ser Pro Phe Val Lys Pro Asn 
                165                 170                 175     


Pro Gly Ser Ser Thr Asp Gly Asn Ser Ala Gly His Ser Gly Asn Asn 
            180                 185                 190         


Ile Leu Gly Ser Glu Val Ala Leu Phe Ala 
        195                 200         


<210>  378
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  378

Leu Ser Leu Glu Pro Val Tyr Trp Asn Ser Ala Asn Lys Arg Phe Gln 
1               5                   10                  15      


Ala Glu Gly Gly Tyr Val Leu Tyr Pro Gln Ile Gly Asp Arg Leu Asp 
            20                  25                  30          


Leu Leu Cys Pro Arg Ala Arg Pro Pro Gly Pro His Ser Ser Pro Asn 
        35                  40                  45              


Tyr Glu Phe Tyr Lys Leu Tyr Leu Val Gly Gly Ala Gln Gly Arg Arg 
    50                  55                  60                  


Cys Glu Ala Pro Pro Ala Pro Asn Leu Leu Leu Thr Cys Asp Arg Pro 
65                  70                  75                  80  


Asp Leu Asp Leu Arg Phe Thr Ile Lys Phe Gln Glu Tyr Ser Pro Asn 
                85                  90                  95      


Leu Trp Gly His Glu Phe Arg Ser His His Asp Tyr Tyr Ile Ile Ala 
            100                 105                 110         


Thr Ser Asp Gly Thr Arg Glu Gly Leu Glu Ser Leu Gln Gly Gly Val 
        115                 120                 125             


Cys Leu Thr Arg Gly Met Lys Val Leu Leu Arg Val Gly Gln Ser Pro 
    130                 135                 140                 


Arg Gly Gly Ala Val Pro Arg Lys Pro Val Ser Glu Met Pro Met Glu 
145                 150                 155                 160 


Arg Asp Arg Gly Ala Ala His Ser Leu Glu Pro Gly Lys Glu Asn Leu 
                165                 170                 175     


Pro Gly Asp Pro Thr Ser Asn Ala Thr Ser Arg Gly Ala Glu Gly Pro 
            180                 185                 190         


Leu Pro Pro Pro Ser Met Pro 
        195                 


<210>  379
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  379

Asn Ser Asp Ser Glu Cys Pro Leu Ser His Asp Gly Tyr Cys Leu His 
1               5                   10                  15      


Asp Gly Val Cys Met Tyr Ile Glu Ala Leu Asp Lys Tyr Ala Cys Asn 
            20                  25                  30          


Cys Val Val Gly Tyr Ile Gly Glu Arg Cys Gln Tyr Arg Asp Leu Lys 
        35                  40                  45              


Trp Trp Glu Leu Arg 
    50              


<210>  380
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  380

His Leu Glu Cys Ser Cys His Asn Asn Ser Thr Cys Glu Pro Ala Thr 
1               5                   10                  15      


Gly Thr Cys Arg Cys Gly Pro Gly Phe Tyr Gly Gln Ala Cys Glu His 
            20                  25                  30          


Pro Cys Pro Pro Gly Phe His Gly Ala Gly Cys Gln Gly Leu Cys Trp 
        35                  40                  45              


Cys Gln His Gly Ala Pro Cys Asp Pro Ile Ser Gly Arg Cys Leu Cys 
    50                  55                  60                  


Pro Ala Gly Phe His Gly His Phe Cys Glu Arg Gly Cys Glu Pro Gly 
65                  70                  75                  80  


Ser Phe Gly Glu Gly Cys His Gln Arg Cys Asp Cys Asp Gly Gly Ala 
                85                  90                  95      


Pro Cys Asp Pro Val Thr Gly Leu Cys Leu Cys Pro Pro Gly Arg Ser 
            100                 105                 110         


Gly Ala Thr Cys Asn Leu Asp Cys Arg Arg Gly Gln Phe Gly Pro Ser 
        115                 120                 125             


Cys Thr Leu His Cys Asp Cys Gly Gly Gly Ala Asp Cys Asp Pro Val 
    130                 135                 140                 


Ser Gly Gln Cys His Cys Val Asp Gly Tyr Met Gly Pro Thr Cys Arg 
145                 150                 155                 160 


Glu Gly Gly Pro Leu Arg Leu Pro Glu Asn Pro Ser Leu Ala Gln Gly 
                165                 170                 175     


Ser Ala Gly Thr Leu Pro Ala Ser Ser Arg Pro Thr Ser Arg Ser Gly 
            180                 185                 190         


Gly Pro Ala Arg His 
        195         


<210>  381
<211>  532
<212>  PRT
<213>  Homo Sapiens

<400>  381

Asn Ala Ala Ser Ala Arg His His Gly Leu Leu Ala Ser Ala Arg Gln 
1               5                   10                  15      


Pro Gly Val Cys His Tyr Gly Thr Lys Leu Ala Cys Cys Tyr Gly Trp 
            20                  25                  30          


Arg Arg Asn Ser Lys Gly Val Cys Glu Ala Thr Cys Glu Pro Gly Cys 
        35                  40                  45              


Lys Phe Gly Glu Cys Val Gly Pro Asn Lys Cys Arg Cys Phe Pro Gly 
    50                  55                  60                  


Tyr Thr Gly Lys Thr Cys Ser Gln Asp Val Asn Glu Cys Gly Met Lys 
65                  70                  75                  80  


Pro Arg Pro Cys Gln His Arg Cys Val Asn Thr His Gly Ser Tyr Lys 
                85                  90                  95      


Cys Phe Cys Leu Ser Gly His Met Leu Met Pro Asp Ala Thr Cys Val 
            100                 105                 110         


Asn Ser Arg Thr Cys Ala Met Ile Asn Cys Gln Tyr Ser Cys Glu Asp 
        115                 120                 125             


Thr Glu Glu Gly Pro Gln Cys Leu Cys Pro Ser Ser Gly Leu Arg Leu 
    130                 135                 140                 


Ala Pro Asn Gly Arg Asp Cys Leu Asp Ile Asp Glu Cys Ala Ser Gly 
145                 150                 155                 160 


Lys Val Ile Cys Pro Tyr Asn Arg Arg Cys Val Asn Thr Phe Gly Ser 
                165                 170                 175     


Tyr Tyr Cys Lys Cys His Ile Gly Phe Glu Leu Gln Tyr Ile Ser Gly 
            180                 185                 190         


Arg Tyr Asp Cys Ile Asp Ile Asn Glu Cys Thr Met Asp Ser His Thr 
        195                 200                 205             


Cys Ser His His Ala Asn Cys Phe Asn Thr Gln Gly Ser Phe Lys Cys 
    210                 215                 220                 


Lys Cys Lys Gln Gly Tyr Lys Gly Asn Gly Leu Arg Cys Ser Ala Ile 
225                 230                 235                 240 


Pro Glu Asn Ser Val Lys Glu Val Leu Arg Ala Pro Gly Thr Ile Lys 
                245                 250                 255     


Asp Arg Ile Lys Lys Leu Leu Ala His Lys Asn Ser Met Lys Lys Lys 
            260                 265                 270         


Ala Lys Ile Lys Asn Val Thr Pro Glu Pro Thr Arg Thr Pro Thr Pro 
        275                 280                 285             


Lys Val Asn Leu Gln Pro Phe Asn Tyr Glu Glu Ile Val Ser Arg Gly 
    290                 295                 300                 


Gly Asn Ser His Gly Gly Lys Lys Gly Asn Glu Glu Lys Met Lys Glu 
305                 310                 315                 320 


Gly Leu Glu Asp Glu Lys Arg Glu Glu Lys Ala Leu Lys Asn Asp Ile 
                325                 330                 335     


Glu Glu Arg Ser Leu Arg Gly Asp Val Phe Phe Pro Lys Val Asn Glu 
            340                 345                 350         


Ala Gly Glu Phe Gly Leu Ile Leu Val Gln Arg Lys Ala Leu Thr Ser 
        355                 360                 365             


Lys Leu Glu His Lys Asp Leu Asn Ile Ser Val Asp Cys Ser Phe Asn 
    370                 375                 380                 


His Gly Ile Cys Asp Trp Lys Gln Asp Arg Glu Asp Asp Phe Asp Trp 
385                 390                 395                 400 


Asn Pro Ala Asp Arg Asp Asn Ala Ile Gly Phe Tyr Met Ala Val Pro 
                405                 410                 415     


Ala Leu Ala Gly His Lys Lys Asp Ile Gly Arg Leu Lys Leu Leu Leu 
            420                 425                 430         


Pro Asp Leu Gln Pro Gln Ser Asn Phe Cys Leu Leu Phe Asp Tyr Arg 
        435                 440                 445             


Leu Ala Gly Asp Lys Val Gly Lys Leu Arg Val Phe Val Lys Asn Ser 
    450                 455                 460                 


Asn Asn Ala Leu Ala Trp Glu Lys Thr Thr Ser Glu Asp Glu Lys Trp 
465                 470                 475                 480 


Lys Thr Gly Lys Ile Gln Leu Tyr Gln Gly Thr Asp Ala Thr Lys Ser 
                485                 490                 495     


Ile Ile Phe Glu Ala Glu Arg Gly Lys Gly Lys Thr Gly Glu Ile Ala 
            500                 505                 510         


Val Asp Gly Val Leu Leu Val Ser Gly Leu Cys Pro Asp Ser Leu Leu 
        515                 520                 525             


Ser Val Asp Asp 
    530         


<210>  382
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  382

Tyr Arg Pro Gly Arg Arg Val Cys Ala Val Arg Ala His Gly Asp Pro 
1               5                   10                  15      


Val Ser Glu Ser Phe Val Gln Arg Val Tyr Gln Pro Phe Leu Thr Thr 
            20                  25                  30          


Cys Asp Gly His Arg Ala Cys Ser Thr Tyr Arg Thr Ile Tyr Arg Thr 
        35                  40                  45              


Ala Tyr Arg Arg Ser Pro Gly Leu Ala Pro Ala Arg Pro Arg Tyr Ala 
    50                  55                  60                  


Cys Cys Pro Gly Trp Lys Arg Thr Ser Gly Leu Pro Gly Ala Cys Gly 
65                  70                  75                  80  


Ala Ala Ile Cys Gln Pro Pro Cys Arg Asn Gly Gly Ser Cys Val Gln 
                85                  90                  95      


Pro Gly Arg Cys Arg Cys Pro Ala Gly Trp Arg Gly Asp Thr Cys Gln 
            100                 105                 110         


Ser Asp Val Asp Glu Cys Ser Ala Arg Arg Gly Gly Cys Pro Gln Arg 
        115                 120                 125             


Cys Ile Asn Thr Ala Gly Ser Tyr Trp Cys Gln Cys Trp Glu Gly His 
    130                 135                 140                 


Ser Leu Ser Ala Asp Gly Thr Leu Cys Val Pro Lys Gly Gly Pro Pro 
145                 150                 155                 160 


Arg Val Ala Pro Asn Pro Thr Gly Val Asp Ser Ala Met Lys Glu Glu 
                165                 170                 175     


Val Gln Arg Leu Gln Ser Arg Val Asp Leu Leu Glu Glu Lys Leu Gln 
            180                 185                 190         


Leu Val Leu Ala Pro Leu His Ser Leu Ala Ser Gln Ala Leu Glu His 
        195                 200                 205             


Gly Leu Pro Asp Pro Gly Ser Leu Leu Val His Ser Phe Gln Gln Leu 
    210                 215                 220                 


Gly Arg Ile Asp Ser Leu Ser Glu Gln Ile Ser Phe Leu Glu Glu Gln 
225                 230                 235                 240 


Leu Gly Ser Cys Ser Cys Lys Lys Asp Ser 
                245                 250 


<210>  383
<211>  985
<212>  PRT
<213>  Homo Sapiens

<400>  383

Leu Arg Ala Ala Ile Arg Lys Pro Gly Lys Val Gly Pro Pro Leu Asp 
1               5                   10                  15      


Ile Lys Leu Gly Ala Leu Asn Cys Thr Ala Phe Ser Ile Gln Trp Lys 
            20                  25                  30          


Met Pro Arg His Pro Gly Ser Pro Ile Leu Gly Tyr Thr Val Phe Tyr 
        35                  40                  45              


Ser Glu Val Gly Ala Asp Lys Ser Leu Gln Glu Gln Leu His Ser Val 
    50                  55                  60                  


Pro Leu Ser Arg Asp Ile Pro Thr Thr Glu Glu Val Ile Gly Asp Leu 
65                  70                  75                  80  


Lys Pro Gly Thr Glu Tyr Arg Val Ser Ile Ala Ala Tyr Ser Gln Ala 
                85                  90                  95      


Gly Lys Gly Arg Leu Ser Ser Pro Arg His Val Thr Thr Leu Ser Gln 
            100                 105                 110         


Asp Ser Cys Leu Pro Pro Ala Ala Pro Gln Gln Pro His Val Ile Val 
        115                 120                 125             


Val Ser Asp Ser Glu Val Ala Leu Ser Trp Lys Pro Gly Ala Ser Glu 
    130                 135                 140                 


Gly Ser Ala Pro Ile Gln Tyr Tyr Ser Val Glu Phe Ile Arg Pro Asp 
145                 150                 155                 160 


Phe Asp Lys Lys Trp Thr Ser Ile His Glu Arg Ile Gln Met Asp Ser 
                165                 170                 175     


Met Val Ile Lys Gly Leu Asp Pro Asp Thr Asn Tyr Gln Phe Ala Val 
            180                 185                 190         


Arg Ala Met Asn Ser His Gly Pro Ser Pro Arg Ser Trp Pro Ser Asp 
        195                 200                 205             


Ile Ile Arg Thr Leu Cys Pro Glu Glu Ala Gly Ser Gly Arg Tyr Gly 
    210                 215                 220                 


Pro Arg Tyr Ile Thr Asp Met Gly Ala Gly Glu Asp Asp Glu Gly Phe 
225                 230                 235                 240 


Glu Asp Asp Leu Asp Leu Asp Ile Ser Phe Glu Glu Val Lys Pro Leu 
                245                 250                 255     


Pro Ala Thr Lys Gly Gly Asn Lys Lys Phe Leu Val Glu Ser Lys Lys 
            260                 265                 270         


Met Ser Ile Ser Asn Pro Lys Thr Ile Ser Arg Leu Ile Pro Pro Thr 
        275                 280                 285             


Ser Ala Ser Leu Pro Val Thr Thr Val Ala Pro Gln Pro Ile Pro Ile 
    290                 295                 300                 


Gln Arg Lys Gly Lys Asn Gly Val Ala Ile Met Ser Arg Leu Phe Asp 
305                 310                 315                 320 


Met Pro Cys Asp Glu Thr Leu Cys Ser Ala Asp Ser Phe Cys Val Asn 
                325                 330                 335     


Asp Tyr Thr Trp Gly Gly Ser Arg Cys Gln Cys Thr Leu Gly Lys Gly 
            340                 345                 350         


Gly Glu Ser Cys Ser Glu Asp Ile Val Ile Gln Tyr Pro Gln Phe Phe 
        355                 360                 365             


Gly His Ser Tyr Val Thr Phe Glu Pro Leu Lys Asn Ser Tyr Gln Ala 
    370                 375                 380                 


Phe Gln Ile Thr Leu Glu Phe Arg Ala Glu Ala Glu Asp Gly Leu Leu 
385                 390                 395                 400 


Leu Tyr Cys Gly Glu Asn Glu His Gly Arg Gly Asp Phe Met Ser Leu 
                405                 410                 415     


Ala Ile Ile Arg Arg Ser Leu Gln Phe Arg Phe Asn Cys Gly Thr Gly 
            420                 425                 430         


Val Ala Ile Ile Val Ser Glu Thr Lys Ile Lys Leu Gly Gly Trp His 
        435                 440                 445             


Met Val Met Leu Tyr Arg Asp Gly Leu Asn Gly Leu Leu Gln Leu Asn 
    450                 455                 460                 


Asn Gly Thr Pro Val Thr Gly Gln Ser Gln Gly Gln Tyr Ser Lys Ile 
465                 470                 475                 480 


Thr Phe Arg Thr Pro Leu Tyr Leu Gly Gly Ala Pro Ser Ala Tyr Trp 
                485                 490                 495     


Leu Val Arg Ala Thr Gly Thr Asn Arg Gly Phe Gln Gly Cys Val Gln 
            500                 505                 510         


Ser Leu Ala Val Asn Gly Arg Arg Ile Asp Met Arg Pro Trp Pro Leu 
        515                 520                 525             


Gly Lys Ala Leu Ser Gly Ala Asp Val Gly Glu Cys Ser Ser Gly Ile 
    530                 535                 540                 


Cys Asp Glu Ala Ser Cys Ile His Gly Gly Thr Cys Thr Ala Ile Lys 
545                 550                 555                 560 


Ala Asp Ser Tyr Ile Cys Leu Cys Pro Leu Gly Phe Lys Gly Arg His 
                565                 570                 575     


Cys Glu Asp Ala Phe Thr Leu Thr Ile Pro Gln Phe Arg Glu Ser Leu 
            580                 585                 590         


Arg Ser Tyr Ala Ala Thr Pro Trp Pro Leu Glu Pro Gln His Tyr Leu 
        595                 600                 605             


Ser Phe Met Glu Phe Glu Ile Thr Phe Arg Pro Asp Ser Gly Asp Gly 
    610                 615                 620                 


Val Leu Leu Tyr Ser Tyr Asp Thr Gly Ser Lys Asp Phe Leu Ser Ile 
625                 630                 635                 640 


Asn Leu Ala Gly Gly His Val Glu Phe Arg Phe Asp Cys Gly Ser Gly 
                645                 650                 655     


Thr Gly Val Leu Arg Ser Glu Asp Pro Leu Thr Leu Gly Asn Trp His 
            660                 665                 670         


Glu Leu Arg Val Ser Arg Thr Ala Lys Asn Gly Ile Leu Gln Val Asp 
        675                 680                 685             


Lys Gln Lys Ile Val Glu Gly Met Ala Glu Gly Gly Phe Thr Gln Ile 
    690                 695                 700                 


Lys Cys Asn Thr Asp Ile Phe Ile Gly Gly Val Pro Asn Tyr Asp Asp 
705                 710                 715                 720 


Val Lys Lys Asn Ser Gly Val Leu Lys Pro Phe Ser Gly Ser Ile Gln 
                725                 730                 735     


Lys Ile Ile Leu Asn Asp Arg Thr Ile His Val Lys His Asp Phe Thr 
            740                 745                 750         


Ser Gly Val Asn Val Glu Asn Ala Ala His Pro Cys Val Arg Ala Pro 
        755                 760                 765             


Cys Ala His Gly Gly Ser Cys Arg Pro Arg Lys Glu Gly Tyr Asp Cys 
    770                 775                 780                 


Asp Cys Pro Leu Gly Phe Glu Gly Leu His Cys Gln Lys Ala Ile Ile 
785                 790                 795                 800 


Glu Ala Ile Glu Ile Pro Gln Phe Ile Gly Arg Ser Tyr Leu Thr Tyr 
                805                 810                 815     


Asp Asn Pro Asp Ile Leu Lys Arg Val Ser Gly Ser Arg Ser Asn Val 
            820                 825                 830         


Phe Met Arg Phe Lys Thr Thr Ala Lys Asp Gly Leu Leu Leu Trp Arg 
        835                 840                 845             


Gly Asp Ser Pro Met Arg Pro Asn Ser Asp Phe Ile Ser Leu Gly Leu 
    850                 855                 860                 


Arg Asp Gly Ala Leu Val Phe Ser Tyr Asn Leu Gly Ser Gly Val Ala 
865                 870                 875                 880 


Ser Ile Met Val Asn Gly Ser Phe Asn Asp Gly Arg Trp His Arg Val 
                885                 890                 895     


Lys Ala Val Arg Asp Gly Gln Ser Gly Lys Ile Thr Val Asp Asp Tyr 
            900                 905                 910         


Gly Ala Arg Thr Gly Lys Ser Pro Gly Met Met Arg Gln Leu Asn Ile 
        915                 920                 925             


Asn Gly Ala Leu Tyr Val Gly Gly Met Lys Glu Ile Ala Leu His Thr 
    930                 935                 940                 


Asn Arg Gln Tyr Met Arg Gly Leu Val Gly Cys Ile Ser His Phe Thr 
945                 950                 955                 960 


Leu Ser Thr Asp Tyr His Ile Ser Leu Val Glu Asp Ala Val Asp Gly 
                965                 970                 975     


Lys Asn Ile Asn Thr Cys Gly Ala Lys 
            980                 985 


<210>  384
<211>  621
<212>  PRT
<213>  Homo Sapiens

<400>  384

Leu Glu Glu Lys Lys Val Cys Gln Gly Thr Ser Asn Lys Leu Thr Gln 
1               5                   10                  15      


Leu Gly Thr Phe Glu Asp His Phe Leu Ser Leu Gln Arg Met Phe Asn 
            20                  25                  30          


Asn Cys Glu Val Val Leu Gly Asn Leu Glu Ile Thr Tyr Val Gln Arg 
        35                  40                  45              


Asn Tyr Asp Leu Ser Phe Leu Lys Thr Ile Gln Glu Val Ala Gly Tyr 
    50                  55                  60                  


Val Leu Ile Ala Leu Asn Thr Val Glu Arg Ile Pro Leu Glu Asn Leu 
65                  70                  75                  80  


Gln Ile Ile Arg Gly Asn Met Tyr Tyr Glu Asn Ser Tyr Ala Leu Ala 
                85                  90                  95      


Val Leu Ser Asn Tyr Asp Ala Asn Lys Thr Gly Leu Lys Glu Leu Pro 
            100                 105                 110         


Met Arg Asn Leu Gln Glu Ile Leu His Gly Ala Val Arg Phe Ser Asn 
        115                 120                 125             


Asn Pro Ala Leu Cys Asn Val Glu Ser Ile Gln Trp Arg Asp Ile Val 
    130                 135                 140                 


Ser Ser Asp Phe Leu Ser Asn Met Ser Met Asp Phe Gln Asn His Leu 
145                 150                 155                 160 


Gly Ser Cys Gln Lys Cys Asp Pro Ser Cys Pro Asn Gly Ser Cys Trp 
                165                 170                 175     


Gly Ala Gly Glu Glu Asn Cys Gln Lys Leu Thr Lys Ile Ile Cys Ala 
            180                 185                 190         


Gln Gln Cys Ser Gly Arg Cys Arg Gly Lys Ser Pro Ser Asp Cys Cys 
        195                 200                 205             


His Asn Gln Cys Ala Ala Gly Cys Thr Gly Pro Arg Glu Ser Asp Cys 
    210                 215                 220                 


Leu Val Cys Arg Lys Phe Arg Asp Glu Ala Thr Cys Lys Asp Thr Cys 
225                 230                 235                 240 


Pro Pro Leu Met Leu Tyr Asn Pro Thr Thr Tyr Gln Met Asp Val Asn 
                245                 250                 255     


Pro Glu Gly Lys Tyr Ser Phe Gly Ala Thr Cys Val Lys Lys Cys Pro 
            260                 265                 270         


Arg Asn Tyr Val Val Thr Asp His Gly Ser Cys Val Arg Ala Cys Gly 
        275                 280                 285             


Ala Asp Ser Tyr Glu Met Glu Glu Asp Gly Val Arg Lys Cys Lys Lys 
    290                 295                 300                 


Cys Glu Gly Pro Cys Arg Lys Val Cys Asn Gly Ile Gly Ile Gly Glu 
305                 310                 315                 320 


Phe Lys Asp Ser Leu Ser Ile Asn Ala Thr Asn Ile Lys His Phe Lys 
                325                 330                 335     


Asn Cys Thr Ser Ile Ser Gly Asp Leu His Ile Leu Pro Val Ala Phe 
            340                 345                 350         


Arg Gly Asp Ser Phe Thr His Thr Pro Pro Leu Asp Pro Gln Glu Leu 
        355                 360                 365             


Asp Ile Leu Lys Thr Val Lys Glu Ile Thr Gly Phe Leu Leu Ile Gln 
    370                 375                 380                 


Ala Trp Pro Glu Asn Arg Thr Asp Leu His Ala Phe Glu Asn Leu Glu 
385                 390                 395                 400 


Ile Ile Arg Gly Arg Thr Lys Gln His Gly Gln Phe Ser Leu Ala Val 
                405                 410                 415     


Val Ser Leu Asn Ile Thr Ser Leu Gly Leu Arg Ser Leu Lys Glu Ile 
            420                 425                 430         


Ser Asp Gly Asp Val Ile Ile Ser Gly Asn Lys Asn Leu Cys Tyr Ala 
        435                 440                 445             


Asn Thr Ile Asn Trp Lys Lys Leu Phe Gly Thr Ser Gly Gln Lys Thr 
    450                 455                 460                 


Lys Ile Ile Ser Asn Arg Gly Glu Asn Ser Cys Lys Ala Thr Gly Gln 
465                 470                 475                 480 


Val Cys His Ala Leu Cys Ser Pro Glu Gly Cys Trp Gly Pro Glu Pro 
                485                 490                 495     


Arg Asp Cys Val Ser Cys Arg Asn Val Ser Arg Gly Arg Glu Cys Val 
            500                 505                 510         


Asp Lys Cys Asn Leu Leu Glu Gly Glu Pro Arg Glu Phe Val Glu Asn 
        515                 520                 525             


Ser Glu Cys Ile Gln Cys His Pro Glu Cys Leu Pro Gln Ala Met Asn 
    530                 535                 540                 


Ile Thr Cys Thr Gly Arg Gly Pro Asp Asn Cys Ile Gln Cys Ala His 
545                 550                 555                 560 


Tyr Ile Asp Gly Pro His Cys Val Lys Thr Cys Pro Ala Gly Val Met 
                565                 570                 575     


Gly Glu Asn Asn Thr Leu Val Trp Lys Tyr Ala Asp Ala Gly His Val 
            580                 585                 590         


Cys His Leu Cys His Pro Asn Cys Thr Tyr Gly Cys Thr Gly Pro Gly 
        595                 600                 605             


Leu Glu Gly Cys Pro Thr Asn Gly Pro Lys Ile Pro Ser 
    610                 615                 620     


<210>  385
<211>  391
<212>  PRT
<213>  Homo Sapiens

<400>  385

Asp Cys Trp Leu Ile Glu Gly Asp Lys Gly Phe Val Trp Leu Ala Ile 
1               5                   10                  15      


Cys Ser Gln Asn Gln Pro Pro Tyr Glu Ala Ile Pro Gln Gln Ile Asn 
            20                  25                  30          


Ser Thr Ile Val Asp Leu Arg Leu Asn Glu Asn Arg Ile Arg Ser Val 
        35                  40                  45              


Gln Tyr Ala Ser Leu Ser Arg Phe Gly Asn Leu Thr Tyr Leu Asn Leu 
    50                  55                  60                  


Thr Lys Asn Glu Ile Gly Tyr Ile Glu Asp Gly Ala Phe Ser Gly Gln 
65                  70                  75                  80  


Phe Asn Leu Gln Val Leu Gln Leu Gly Tyr Asn Arg Leu Arg Asn Leu 
                85                  90                  95      


Thr Glu Gly Met Leu Arg Gly Leu Gly Lys Leu Glu Tyr Leu Tyr Leu 
            100                 105                 110         


Gln Ala Asn Leu Ile Glu Val Val Met Ala Ser Ser Phe Trp Glu Cys 
        115                 120                 125             


Pro Asn Ile Val Asn Ile Asp Leu Ser Met Asn Arg Ile Gln Gln Leu 
    130                 135                 140                 


Asn Ser Gly Thr Phe Ala Gly Leu Ala Lys Leu Ser Val Cys Glu Leu 
145                 150                 155                 160 


Tyr Ser Asn Pro Phe Tyr Cys Ser Cys Glu Leu Leu Gly Phe Leu Arg 
                165                 170                 175     


Trp Leu Ala Ala Phe Thr Asn Ala Thr Gln Thr Tyr Asp Arg Met Gln 
            180                 185                 190         


Cys Glu Ser Pro Pro Val Tyr Ser Gly Tyr Tyr Leu Leu Gly Gln Gly 
        195                 200                 205             


Arg Arg Gly His Arg Ser Ile Leu Ser Lys Leu Gln Ser Val Cys Thr 
    210                 215                 220                 


Glu Asp Ser Tyr Ala Ala Glu Val Val Gly Pro Pro Arg Pro Ala Ser 
225                 230                 235                 240 


Gly Arg Ser Gln Pro Gly Arg Ser Pro Pro Pro Pro Pro Pro Pro Glu 
                245                 250                 255     


Pro Ser Asp Met Pro Cys Ala Asp Asp Glu Cys Phe Ser Gly Asp Gly 
            260                 265                 270         


Thr Thr Pro Leu Val Ala Leu Pro Thr Leu Ala Thr Gln Ala Glu Ala 
        275                 280                 285             


Arg Pro Leu Ile Lys Val Lys Gln Leu Thr Gln Asn Ser Ala Thr Ile 
    290                 295                 300                 


Thr Val Gln Leu Pro Ser Pro Phe His Arg Met Tyr Thr Leu Glu His 
305                 310                 315                 320 


Phe Asn Asn Ser Lys Ala Ser Thr Val Ser Arg Leu Thr Lys Ala Gln 
                325                 330                 335     


Glu Glu Ile Arg Leu Thr Asn Leu Phe Thr Leu Thr Asn Tyr Thr Tyr 
            340                 345                 350         


Cys Val Val Ser Thr Ser Ala Gly Leu Arg His Asn His Thr Cys Leu 
        355                 360                 365             


Thr Ile Cys Leu Pro Arg Leu Pro Ser Pro Pro Gly Pro Val Pro Ser 
    370                 375                 380                 


Pro Ser Thr Ala Thr His Tyr 
385                 390     


<210>  386
<211>  375
<212>  PRT
<213>  Homo Sapiens

<400>  386

Asp Cys Trp Leu Ile Glu Gly Asp Lys Gly Tyr Val Trp Leu Ala Ile 
1               5                   10                  15      


Cys Ser Gln Asn Gln Pro Pro Tyr Glu Thr Ile Pro Gln His Ile Asn 
            20                  25                  30          


Ser Thr Val His Asp Leu Arg Leu Asn Glu Asn Lys Leu Lys Ala Val 
        35                  40                  45              


Leu Tyr Ser Ser Leu Asn Arg Phe Gly Asn Leu Thr Asp Leu Asn Leu 
    50                  55                  60                  


Thr Lys Asn Glu Ile Ser Tyr Ile Glu Asp Gly Ala Phe Leu Gly Gln 
65                  70                  75                  80  


Ser Ser Leu Gln Val Leu Gln Leu Gly Tyr Asn Lys Leu Ser Asn Leu 
                85                  90                  95      


Thr Glu Gly Met Leu Arg Gly Met Ser Arg Leu Gln Phe Leu Phe Val 
            100                 105                 110         


Gln His Asn Leu Ile Glu Val Val Thr Pro Thr Ala Phe Ser Glu Cys 
        115                 120                 125             


Pro Ser Leu Ile Ser Ile Asp Leu Ser Ser Asn Arg Leu Ser Arg Leu 
    130                 135                 140                 


Asp Gly Ala Thr Phe Ala Ser Leu Ala Ser Leu Met Val Cys Glu Leu 
145                 150                 155                 160 


Ala Gly Asn Pro Phe Asn Cys Glu Cys Asp Leu Phe Gly Phe Leu Ala 
                165                 170                 175     


Trp Leu Val Val Phe Asn Asn Val Thr Lys Asn Tyr Asp Arg Leu Gln 
            180                 185                 190         


Cys Glu Ser Pro Arg Glu Phe Ala Gly Tyr Pro Leu Leu Val Pro Arg 
        195                 200                 205             


Pro Tyr His Ser Leu Asn Ala Ile Thr Val Leu Gln Ala Lys Cys Arg 
    210                 215                 220                 


Asn Gly Ser Leu Pro Ala Arg Pro Val Ser His Pro Thr Pro Tyr Ser 
225                 230                 235                 240 


Thr Asp Ala Gln Arg Glu Pro Asp Glu Asn Ser Gly Phe Asn Pro Asp 
                245                 250                 255     


Glu Ile Leu Ser Val Glu Pro Pro Ala Ser Ser Thr Thr Asp Ala Ser 
            260                 265                 270         


Ala Gly Pro Ala Ile Lys Leu His His Val Thr Phe Thr Ser Ala Thr 
        275                 280                 285             


Leu Val Val Ile Ile Pro His Pro Tyr Ser Lys Met Tyr Ile Leu Val 
    290                 295                 300                 


Gln Tyr Asn Asn Ser Tyr Phe Ser Asp Val Met Thr Leu Lys Asn Lys 
305                 310                 315                 320 


Lys Glu Ile Val Thr Leu Asp Lys Leu Arg Ala His Thr Glu Tyr Thr 
                325                 330                 335     


Phe Cys Val Thr Ser Leu Arg Asn Ser Arg Arg Phe Asn His Thr Cys 
            340                 345                 350         


Leu Thr Phe Thr Thr Arg Asp Pro Val Pro Gly Asp Leu Ala Pro Ser 
        355                 360                 365             


Thr Ser Thr Thr Thr His Tyr 
    370                 375 


<210>  387
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  387

Met His Glu Glu Cys Val Phe Pro Phe Thr Tyr Lys Gly Ser Val Tyr 
1               5                   10                  15      


Phe Thr Cys Thr His Ile His Ser Leu Ser Pro Trp Cys Ala Thr Arg 
            20                  25                  30          


Ala Val Tyr Asn Gly Gln Trp Lys Tyr Cys Gln Ser Glu Asp Tyr Pro 
        35                  40                  45              


Arg Cys Ile Phe Pro Phe Ile Tyr Arg Gly Lys Ala Tyr Asn Ser Cys 
    50                  55                  60                  


Ile Ser Gln Gly Ser Phe Leu Gly Ser Leu Trp Cys Ser Val Thr Ser 
65                  70                  75                  80  


Val Phe Asp Glu Lys Gln Gln Trp Lys Phe Cys Glu Thr Asn Glu Tyr 
                85                  90                  95      


Gly Gly Asn Ser Leu Arg Lys Pro Cys Ile Phe Pro Ser Ile Tyr Arg 
            100                 105                 110         


Asn Asn Val Val Ser Asp Cys Met Glu Asp Glu Ser Asn Lys Leu Trp 
        115                 120                 125             


Cys Pro Thr Thr Glu Asn Met Asp Lys Asp Gly Lys Trp Ser Phe Cys 
    130                 135                 140                 


Ala Asp Thr Arg Ile Ser Ala Leu Val Pro Gly Phe Pro Cys His Phe 
145                 150                 155                 160 


Pro Phe Asn Tyr Lys Asn Lys Asn Tyr Phe Asn Cys Thr Asn Lys Gly 
                165                 170                 175     


Ser Lys Glu Asn Leu Val Trp Cys Ala Thr Ser Tyr Asn Tyr Asp Gln 
            180                 185                 190         


Asp His Thr Trp Val Tyr Cys 
        195                 


<210>  388
<211>  413
<212>  PRT
<213>  Homo Sapiens

<400>  388

Gln Asn Cys Thr Lys Thr Pro Cys Leu Pro Asn Ala Lys Cys Glu Ile 
1               5                   10                  15      


Arg Asn Gly Ile Glu Ala Cys Tyr Cys Asn Met Gly Phe Ser Gly Asn 
            20                  25                  30          


Gly Val Thr Ile Cys Glu Asp Asp Asn Glu Cys Gly Asn Leu Thr Gln 
        35                  40                  45              


Ser Cys Gly Glu Asn Ala Asn Cys Thr Asn Thr Glu Gly Ser Tyr Tyr 
    50                  55                  60                  


Cys Met Cys Val Pro Gly Phe Arg Ser Ser Ser Asn Gln Asp Arg Phe 
65                  70                  75                  80  


Ile Thr Asn Asp Gly Thr Val Cys Ile Glu Asn Val Asn Ala Asn Cys 
                85                  90                  95      


His Leu Asp Asn Val Cys Ile Ala Ala Asn Ile Asn Lys Thr Leu Thr 
            100                 105                 110         


Lys Ile Arg Ser Ile Lys Glu Pro Val Ala Leu Leu Gln Glu Val Tyr 
        115                 120                 125             


Arg Asn Ser Val Thr Asp Leu Ser Pro Thr Asp Ile Ile Thr Tyr Ile 
    130                 135                 140                 


Glu Ile Leu Ala Glu Ser Ser Ser Leu Leu Gly Tyr Lys Asn Asn Thr 
145                 150                 155                 160 


Ile Ser Ala Lys Asp Thr Leu Ser Asn Ser Thr Leu Thr Glu Phe Val 
                165                 170                 175     


Lys Thr Val Asn Asn Phe Val Gln Arg Asp Thr Phe Val Val Trp Asp 
            180                 185                 190         


Lys Leu Ser Val Asn His Arg Arg Thr His Leu Thr Lys Leu Met His 
        195                 200                 205             


Thr Val Glu Gln Ala Thr Leu Arg Ile Ser Gln Ser Phe Gln Lys Thr 
    210                 215                 220                 


Thr Glu Phe Asp Thr Asn Ser Thr Asp Ile Ala Leu Lys Val Phe Phe 
225                 230                 235                 240 


Phe Asp Ser Tyr Asn Met Lys His Ile His Pro His Met Asn Met Asp 
                245                 250                 255     


Gly Asp Tyr Ile Asn Ile Phe Pro Lys Arg Lys Ala Ala Tyr Asp Ser 
            260                 265                 270         


Asn Gly Asn Val Ala Val Ala Phe Val Tyr Tyr Lys Ser Ile Gly Pro 
        275                 280                 285             


Leu Leu Ser Ser Ser Asp Asn Phe Leu Leu Lys Pro Gln Asn Tyr Asp 
    290                 295                 300                 


Asn Ser Glu Glu Glu Glu Arg Val Ile Ser Ser Val Ile Ser Val Ser 
305                 310                 315                 320 


Met Ser Ser Asn Pro Pro Thr Leu Tyr Glu Leu Glu Lys Ile Thr Phe 
                325                 330                 335     


Thr Leu Ser His Arg Lys Val Thr Asp Arg Tyr Arg Ser Leu Cys Ala 
            340                 345                 350         


Phe Trp Asn Tyr Ser Pro Asp Thr Met Asn Gly Ser Trp Ser Ser Glu 
        355                 360                 365             


Gly Cys Glu Leu Thr Tyr Ser Asn Glu Thr His Thr Ser Cys Arg Cys 
    370                 375                 380                 


Asn His Leu Thr His Phe Ala Ile Leu Met Ser Ser Gly Pro Ser Ile 
385                 390                 395                 400 


Gly Ile Lys Asp Tyr Asn Ile Leu Thr Arg Ile Thr Gln 
                405                 410             


<210>  389
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  389

Asp Gly Ser Ala Pro Asp Ser Pro Phe Thr Ser Pro Pro Leu Arg Glu 
1               5                   10                  15      


Glu Ile Met Ala Asn Asn Phe Ser Leu Glu Ser His Asn Ile Ser Leu 
            20                  25                  30          


Thr Glu His Ser Ser Met Pro Val Glu Lys Asn Ile Thr Leu Glu Arg 
        35                  40                  45              


Pro Ser Asn Val Asn Leu Thr Cys Gln Phe Thr Thr Ser Gly Asp Leu 
    50                  55                  60                  


Asn Ala Val Asn Val Thr Trp Lys Lys Asp Gly Glu Gln Leu Glu Asn 
65                  70                  75                  80  


Asn Tyr Leu Val Ser Ala Thr Gly Ser Thr Leu Tyr Thr Gln Tyr Arg 
                85                  90                  95      


Phe Thr Ile Ile Asn Ser Lys Gln Met Gly Ser Tyr Ser Cys Phe Phe 
            100                 105                 110         


Arg Glu Glu Lys Glu Gln Arg Gly Thr Phe Asn Phe Lys Val Pro Glu 
        115                 120                 125             


Leu His Gly Lys Asn Lys Pro Leu Ile Ser Tyr Val Gly Asp Ser Thr 
    130                 135                 140                 


Val Leu Thr Cys Lys Cys Gln Asn Cys Phe Pro Leu Asn Trp Thr Trp 
145                 150                 155                 160 


Tyr Ser Ser Asn Gly Ser Val Lys Val Pro Val Gly Val Gln Met Asn 
                165                 170                 175     


Lys Tyr Val Ile Asn Gly Thr Tyr Ala Asn Glu Thr Lys Leu Lys Ile 
            180                 185                 190         


Thr Gln Leu Leu Glu Glu Asp Gly Glu Ser Tyr Trp Cys Arg Ala Leu 
        195                 200                 205             


Phe Gln Leu Gly Glu Ser Glu Glu His Ile Glu Leu Val Val Leu Ser 
    210                 215                 220                 


Tyr Leu Val Pro 
225             


<210>  390
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  390

Asn Ser Thr Gly Val Leu Glu Ala Ala Asn Asn Ser Leu Val Val Thr 
1               5                   10                  15      


Thr Thr Lys Pro Ser Ile Thr Thr Pro Asn Thr Glu Ser Leu Gln Lys 
            20                  25                  30          


Asn Val Val Thr Pro Thr Thr Gly Thr Thr Pro Lys Gly Thr Ile Thr 
        35                  40                  45              


Asn Glu Leu Leu Lys Met Ser Leu Met Ser Thr Ala Thr Phe Leu Thr 
    50                  55                  60                  


Ser Lys Asp Glu Gly Leu Lys Ala Thr Thr Thr Asp Val Arg Lys Asn 
65                  70                  75                  80  


Asp Ser Ile Ile Ser Asn Val Thr Val Thr Ser Val Thr Leu Pro Asn 
                85                  90                  95      


Ala Val Ser Thr Leu Gln Ser Ser Lys Pro Lys Thr Glu Thr Gln Ser 
            100                 105                 110         


Ser Ile Lys Thr Thr Glu Ile Pro Gly Thr Pro Glu Asn Gly Asn Asp 
        115                 120                 125             


Gln Pro Gln Ser Asp Lys Glu Ser Val Lys Leu Leu Thr Val Lys Thr 
    130                 135                 140                 


Ile Ser His Glu Ser Gly Glu His Ser Ala Gln Gly Lys Thr Lys Asn 
145                 150                 155                 160 


<210>  391
<211>  579
<212>  PRT
<213>  Homo Sapiens

<400>  391

His Ile Arg Pro Thr Arg Lys Pro Asn Thr Lys Gly Asn Asn Cys Arg 
1               5                   10                  15      


Asp Ser Thr Leu Cys Pro Ala Tyr Ala Thr Cys Thr Asn Thr Val Asp 
            20                  25                  30          


Ser Tyr Tyr Cys Ala Cys Lys Gln Gly Phe Leu Ser Ser Asn Gly Gln 
        35                  40                  45              


Asn His Phe Lys Asp Pro Gly Val Arg Cys Lys Asp Ile Asp Glu Cys 
    50                  55                  60                  


Ser Gln Ser Pro Gln Pro Cys Gly Pro Asn Ser Ser Cys Lys Asn Leu 
65                  70                  75                  80  


Ser Gly Arg Tyr Lys Cys Ser Cys Leu Asp Gly Phe Ser Ser Pro Thr 
                85                  90                  95      


Gly Asn Asp Trp Val Pro Gly Lys Pro Gly Asn Phe Ser Cys Thr Asp 
            100                 105                 110         


Ile Asn Glu Cys Leu Thr Ser Ser Val Cys Pro Glu His Ser Asp Cys 
        115                 120                 125             


Val Asn Ser Met Gly Ser Tyr Ser Cys Ser Cys Gln Val Gly Phe Ile 
    130                 135                 140                 


Ser Arg Asn Ser Thr Cys Glu Asp Val Asp Glu Cys Ala Asp Pro Arg 
145                 150                 155                 160 


Ala Cys Pro Glu His Ala Thr Cys Asn Asn Thr Val Gly Asn Tyr Ser 
                165                 170                 175     


Cys Phe Cys Asn Pro Gly Phe Glu Ser Ser Ser Gly His Leu Ser Phe 
            180                 185                 190         


Gln Gly Leu Lys Ala Ser Cys Glu Asp Ile Asp Glu Cys Thr Glu Met 
        195                 200                 205             


Cys Pro Ile Asn Ser Thr Cys Thr Asn Thr Pro Gly Ser Tyr Phe Cys 
    210                 215                 220                 


Thr Cys His Pro Gly Phe Ala Pro Ser Asn Gly Gln Leu Asn Phe Thr 
225                 230                 235                 240 


Asp Gln Gly Val Glu Cys Arg Asp Ile Asp Glu Cys Arg Gln Asp Pro 
                245                 250                 255     


Ser Thr Cys Gly Pro Asn Ser Ile Cys Thr Asn Ala Leu Gly Ser Tyr 
            260                 265                 270         


Ser Cys Gly Cys Ile Ala Gly Phe His Pro Asn Pro Glu Gly Ser Gln 
        275                 280                 285             


Lys Asp Gly Asn Phe Ser Cys Gln Arg Val Leu Phe Lys Cys Lys Glu 
    290                 295                 300                 


Asp Val Ile Pro Asp Asn Lys Gln Ile Gln Gln Cys Gln Glu Gly Thr 
305                 310                 315                 320 


Ala Val Lys Pro Ala Tyr Val Ser Phe Cys Ala Gln Ile Asn Asn Ile 
                325                 330                 335     


Phe Ser Val Leu Asp Lys Val Cys Glu Asn Lys Thr Thr Val Val Ser 
            340                 345                 350         


Leu Lys Asn Thr Thr Glu Ser Phe Val Pro Val Leu Lys Gln Ile Ser 
        355                 360                 365             


Thr Trp Thr Lys Phe Thr Lys Glu Glu Thr Ser Ser Leu Ala Thr Val 
    370                 375                 380                 


Phe Leu Glu Ser Val Glu Ser Met Thr Leu Ala Ser Phe Trp Lys Pro 
385                 390                 395                 400 


Ser Ala Asn Ile Thr Pro Ala Val Arg Thr Glu Tyr Leu Asp Ile Glu 
                405                 410                 415     


Ser Lys Val Ile Asn Lys Glu Cys Ser Glu Glu Asn Val Thr Leu Asp 
            420                 425                 430         


Leu Val Ala Lys Gly Asp Lys Met Lys Ile Gly Cys Ser Thr Ile Glu 
        435                 440                 445             


Glu Ser Glu Ser Thr Glu Thr Thr Gly Val Ala Phe Val Ser Phe Val 
    450                 455                 460                 


Gly Met Glu Ser Val Leu Asn Glu Arg Phe Phe Lys Asp His Gln Ala 
465                 470                 475                 480 


Pro Leu Thr Thr Ser Glu Ile Lys Leu Lys Met Asn Ser Arg Val Val 
                485                 490                 495     


Gly Gly Ile Met Thr Gly Glu Lys Lys Asp Gly Phe Ser Asp Pro Ile 
            500                 505                 510         


Ile Tyr Thr Leu Glu Asn Ile Gln Pro Lys Gln Lys Phe Glu Arg Pro 
        515                 520                 525             


Ile Cys Val Ser Trp Ser Thr Asp Val Lys Gly Gly Arg Trp Thr Ser 
    530                 535                 540                 


Phe Gly Cys Val Ile Leu Glu Ala Ser Glu Thr Tyr Thr Ile Cys Ser 
545                 550                 555                 560 


Cys Asn Gln Met Ala Asn Leu Ala Val Ile Met Ala Ser Gly Glu Leu 
                565                 570                 575     


Thr Met Asp 
            


<210>  392
<211>  828
<212>  PRT
<213>  Homo Sapiens

<400>  392

Lys Pro Ser Cys Ala Lys Glu Val Lys Ser Cys Lys Gly Arg Cys Phe 
1               5                   10                  15      


Glu Arg Thr Phe Gly Asn Cys Arg Cys Asp Ala Ala Cys Val Glu Leu 
            20                  25                  30          


Gly Asn Cys Cys Leu Asp Tyr Gln Glu Thr Cys Ile Glu Pro Glu His 
        35                  40                  45              


Ile Trp Thr Cys Asn Lys Phe Arg Cys Gly Glu Lys Arg Leu Thr Arg 
    50                  55                  60                  


Ser Leu Cys Ala Cys Ser Asp Asp Cys Lys Asp Lys Gly Asp Cys Cys 
65                  70                  75                  80  


Ile Asn Tyr Ser Ser Val Cys Gln Gly Glu Lys Ser Trp Val Glu Glu 
                85                  90                  95      


Pro Cys Glu Ser Ile Asn Glu Pro Gln Cys Pro Ala Gly Phe Glu Thr 
            100                 105                 110         


Pro Pro Thr Leu Leu Phe Ser Leu Asp Gly Phe Arg Ala Glu Tyr Leu 
        115                 120                 125             


His Thr Trp Gly Gly Leu Leu Pro Val Ile Ser Lys Leu Lys Lys Cys 
    130                 135                 140                 


Gly Thr Tyr Thr Lys Asn Met Arg Pro Val Tyr Pro Thr Lys Thr Phe 
145                 150                 155                 160 


Pro Asn His Tyr Ser Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly 
                165                 170                 175     


Ile Ile Asp Asn Lys Met Tyr Asp Pro Lys Met Asn Ala Ser Phe Ser 
            180                 185                 190         


Leu Lys Ser Lys Glu Lys Phe Asn Pro Glu Trp Tyr Lys Gly Glu Pro 
        195                 200                 205             


Ile Trp Val Thr Ala Lys Tyr Gln Gly Leu Lys Ser Gly Thr Phe Phe 
    210                 215                 220                 


Trp Pro Gly Ser Asp Val Glu Ile Asn Gly Ile Phe Pro Asp Ile Tyr 
225                 230                 235                 240 


Lys Met Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Leu Ala Val 
                245                 250                 255     


Leu Gln Trp Leu Gln Leu Pro Lys Asp Glu Arg Pro His Phe Tyr Thr 
            260                 265                 270         


Leu Tyr Leu Glu Glu Pro Asp Ser Ser Gly His Ser Tyr Gly Pro Val 
        275                 280                 285             


Ser Ser Glu Val Ile Lys Ala Leu Gln Arg Val Asp Gly Met Val Gly 
    290                 295                 300                 


Met Leu Met Asp Gly Leu Lys Glu Leu Asn Leu His Arg Cys Leu Asn 
305                 310                 315                 320 


Leu Ile Leu Ile Ser Asp His Gly Met Glu Gln Gly Ser Cys Lys Lys 
                325                 330                 335     


Tyr Ile Tyr Leu Asn Lys Tyr Leu Gly Asp Val Lys Asn Ile Lys Val 
            340                 345                 350         


Ile Tyr Gly Pro Ala Ala Arg Leu Arg Pro Ser Asp Val Pro Asp Lys 
        355                 360                 365             


Tyr Tyr Ser Phe Asn Tyr Glu Gly Ile Ala Arg Asn Leu Ser Cys Arg 
    370                 375                 380                 


Glu Pro Asn Gln His Phe Lys Pro Tyr Leu Lys His Phe Leu Pro Lys 
385                 390                 395                 400 


Arg Leu His Phe Ala Lys Ser Asp Arg Ile Glu Pro Leu Thr Phe Tyr 
                405                 410                 415     


Leu Asp Pro Gln Trp Gln Leu Ala Leu Asn Pro Ser Glu Arg Lys Tyr 
            420                 425                 430         


Cys Gly Ser Gly Phe His Gly Ser Asp Asn Val Phe Ser Asn Met Gln 
        435                 440                 445             


Ala Leu Phe Val Gly Tyr Gly Pro Gly Phe Lys His Gly Ile Glu Ala 
    450                 455                 460                 


Asp Thr Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu 
465                 470                 475                 480 


Asn Leu Thr Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn His 
                485                 490                 495     


Leu Leu Lys Asn Pro Val Tyr Thr Pro Lys His Pro Lys Glu Val His 
            500                 505                 510         


Pro Leu Val Gln Cys Pro Phe Thr Arg Asn Pro Arg Asp Asn Leu Gly 
        515                 520                 525             


Cys Ser Cys Asn Pro Ser Ile Leu Pro Ile Glu Asp Phe Gln Thr Gln 
    530                 535                 540                 


Phe Asn Leu Thr Val Ala Glu Glu Lys Ile Ile Lys His Glu Thr Leu 
545                 550                 555                 560 


Pro Tyr Gly Arg Pro Arg Val Leu Gln Lys Glu Asn Thr Ile Cys Leu 
                565                 570                 575     


Leu Ser Gln His Gln Phe Met Ser Gly Tyr Ser Gln Asp Ile Leu Met 
            580                 585                 590         


Pro Leu Trp Thr Ser Tyr Thr Val Asp Arg Asn Asp Ser Phe Ser Thr 
        595                 600                 605             


Glu Asp Phe Ser Asn Cys Leu Tyr Gln Asp Phe Arg Ile Pro Leu Ser 
    610                 615                 620                 


Pro Val His Lys Cys Ser Phe Tyr Lys Asn Asn Thr Lys Val Ser Tyr 
625                 630                 635                 640 


Gly Phe Leu Ser Pro Pro Gln Leu Asn Lys Asn Ser Ser Gly Ile Tyr 
                645                 650                 655     


Ser Glu Ala Leu Leu Thr Thr Asn Ile Val Pro Met Tyr Gln Ser Phe 
            660                 665                 670         


Gln Val Ile Trp Arg Tyr Phe His Asp Thr Leu Leu Arg Lys Tyr Ala 
        675                 680                 685             


Glu Glu Arg Asn Gly Val Asn Val Val Ser Gly Pro Val Phe Asp Phe 
    690                 695                 700                 


Asp Tyr Asp Gly Arg Cys Asp Ser Leu Glu Asn Leu Arg Gln Lys Arg 
705                 710                 715                 720 


Arg Val Ile Arg Asn Gln Glu Ile Leu Ile Pro Thr His Phe Phe Ile 
                725                 730                 735     


Val Leu Thr Ser Cys Lys Asp Thr Ser Gln Thr Pro Leu His Cys Glu 
            740                 745                 750         


Asn Leu Asp Thr Leu Ala Phe Ile Leu Pro His Arg Thr Asp Asn Ser 
        755                 760                 765             


Glu Ser Cys Val His Gly Lys His Asp Ser Ser Trp Val Glu Glu Leu 
    770                 775                 780                 


Leu Met Leu His Arg Ala Arg Ile Thr Asp Val Glu His Ile Thr Gly 
785                 790                 795                 800 


Leu Ser Phe Tyr Gln Gln Arg Lys Glu Pro Val Ser Asp Ile Leu Lys 
                805                 810                 815     


Leu Lys Thr His Leu Pro Thr Phe Ser Gln Glu Asp 
            820                 825             


<210>  393
<211>  340
<212>  PRT
<213>  Homo Sapiens

<400>  393

Met Glu Ser Glu Glu Leu Ala Asp Arg Val Leu Asp Val Val Glu Arg 
1               5                   10                  15      


Ser Leu Ser Asn Tyr Pro Phe Asp Phe Gln Gly Ala Arg Ile Ile Thr 
            20                  25                  30          


Gly Gln Glu Glu Gly Ala Tyr Gly Trp Ile Thr Ile Asn Tyr Leu Leu 
        35                  40                  45              


Gly Lys Phe Ser Gln Lys Thr Arg Trp Phe Ser Ile Val Pro Tyr Glu 
    50                  55                  60                  


Thr Asn Asn Gln Glu Thr Phe Gly Ala Leu Asp Leu Gly Gly Ala Ser 
65                  70                  75                  80  


Thr Gln Val Thr Phe Val Pro Gln Asn Gln Thr Ile Glu Ser Pro Asp 
                85                  90                  95      


Asn Ala Leu Gln Phe Arg Leu Tyr Gly Lys Asp Tyr Asn Val Tyr Thr 
            100                 105                 110         


His Ser Phe Leu Cys Tyr Gly Lys Asp Gln Ala Leu Trp Gln Lys Leu 
        115                 120                 125             


Ala Lys Asp Ile Gln Val Ala Ser Asn Glu Ile Leu Arg Asp Pro Cys 
    130                 135                 140                 


Phe His Pro Gly Tyr Lys Lys Val Val Asn Val Ser Asp Leu Tyr Lys 
145                 150                 155                 160 


Thr Pro Cys Thr Lys Arg Phe Glu Met Thr Leu Pro Phe Gln Gln Phe 
                165                 170                 175     


Glu Ile Gln Gly Ile Gly Asn Tyr Gln Gln Cys His Gln Ser Ile Leu 
            180                 185                 190         


Glu Leu Phe Asn Thr Ser Tyr Cys Pro Tyr Ser Gln Cys Ala Phe Asn 
        195                 200                 205             


Gly Ile Phe Leu Pro Pro Leu Gln Gly Asp Phe Gly Ala Phe Ser Ala 
    210                 215                 220                 


Phe Tyr Phe Val Met Lys Phe Leu Asn Leu Thr Ser Glu Lys Val Ser 
225                 230                 235                 240 


Gln Glu Lys Val Thr Glu Met Met Lys Lys Phe Cys Ala Gln Pro Trp 
                245                 250                 255     


Glu Glu Ile Lys Thr Ser Tyr Ala Gly Val Lys Glu Lys Tyr Leu Ser 
            260                 265                 270         


Glu Tyr Cys Phe Ser Gly Thr Tyr Ile Leu Ser Leu Leu Leu Gln Gly 
        275                 280                 285             


Tyr His Phe Thr Ala Asp Ser Trp Glu His Ile His Phe Ile Gly Lys 
    290                 295                 300                 


Ile Gln Gly Ser Asp Ala Gly Trp Thr Leu Gly Tyr Met Leu Asn Leu 
305                 310                 315                 320 


Thr Asn Met Ile Pro Ala Glu Gln Pro Leu Ser Thr Pro Leu Ser His 
                325                 330                 335     


Ser Thr Tyr Val 
            340 


<210>  394
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  394

Gln Ile His Lys Gln Glu Val Leu Pro Pro Gly Leu Lys Tyr Gly Ile 
1               5                   10                  15      


Val Leu Asp Ala Gly Ser Ser Arg Thr Thr Val Tyr Val Tyr Gln Trp 
            20                  25                  30          


Pro Ala Glu Lys Glu Asn Asn Thr Gly Val Val Ser Gln Thr Phe Lys 
        35                  40                  45              


Cys Ser Val Lys Gly Ser Gly Ile Ser Ser Tyr Gly Asn Asn Pro Gln 
    50                  55                  60                  


Asp Val Pro Arg Ala Phe Glu Glu Cys Met Gln Lys Val Lys Gly Gln 
65                  70                  75                  80  


Val Pro Ser His Leu His Gly Ser Thr Pro Ile His Leu Gly Ala Thr 
                85                  90                  95      


Ala Gly Met Arg Leu Leu Arg Leu Gln Asn Glu Thr Ala Ala Asn Glu 
            100                 105                 110         


Val Leu Glu Ser Ile Gln Ser Tyr Phe Lys Ser Gln Pro Phe Asp Phe 
        115                 120                 125             


Arg Gly Ala Gln Ile Ile Ser Gly Gln Glu Glu Gly Val Tyr Gly Trp 
    130                 135                 140                 


Ile Thr Ala Asn Tyr Leu Met Gly Asn Phe Leu Glu Lys Asn Leu Trp 
145                 150                 155                 160 


His Met Trp Val His Pro His Gly Val Glu Thr Thr Gly Ala Leu Asp 
                165                 170                 175     


Leu Gly Gly Ala Ser Thr Gln Ile Ser Phe Val Ala Gly Glu Lys Met 
            180                 185                 190         


Asp Leu Asn Thr Ser Asp Ile Met Gln Val Ser Leu Tyr Gly Tyr Val 
        195                 200                 205             


Tyr Thr Leu Tyr Thr His Ser Phe Gln Cys Tyr Gly Arg Asn Glu Ala 
    210                 215                 220                 


Glu Lys Lys Phe Leu Ala Met Leu Leu Gln Asn Ser Pro Thr Lys Asn 
225                 230                 235                 240 


His Leu Thr Asn Pro Cys Tyr Pro Arg Asp Tyr Ser Ile Ser Phe Thr 
                245                 250                 255     


Met Gly His Val Phe Asp Ser Leu Cys Thr Val Asp Gln Arg Pro Glu 
            260                 265                 270         


Ser Tyr Asn Pro Asn Asp Val Ile Thr Phe Glu Gly Thr Gly Asp Pro 
        275                 280                 285             


Ser Leu Cys Lys Glu Lys Val Ala Ser Ile Phe Asp Phe Lys Ala Cys 
    290                 295                 300                 


His Asp Gln Glu Thr Cys Ser Phe Asp Gly Val Tyr Gln Pro Lys Ile 
305                 310                 315                 320 


Lys Gly Pro Phe Val Ala Phe Ala Gly Phe Tyr Tyr Thr Ala Ser Ala 
                325                 330                 335     


Leu Asn Leu Ser Gly Ser Phe Ser Leu Asp Thr Phe Asn Ser Ser Thr 
            340                 345                 350         


Trp Asn Phe Cys Ser Gln Asn Trp Ser Gln Leu Pro Leu Leu Leu Pro 
        355                 360                 365             


Lys Phe Asp Glu Val Tyr Ala Arg Ser Tyr Cys Phe Ser Ala Asn Tyr 
    370                 375                 380                 


Ile Tyr His Leu Phe Val Asn Gly Tyr Lys Phe Thr Glu Glu Thr Trp 
385                 390                 395                 400 


Pro Gln Ile His Phe Glu Lys Glu Glu 
                405                 


<210>  395
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  395

Ala Ala Val Thr Val Thr Pro Pro Ile Thr Ala Gln Gln Ala Asp Asn 
1               5                   10                  15      


Ile Glu Gly Pro Ile Ala Leu Lys Phe Ser His Leu Cys Leu Glu Asp 
            20                  25                  30          


His Asn Ser Tyr Cys Ile Asn Gly Ala Cys Ala Phe His His Glu Leu 
        35                  40                  45              


Glu Lys Ala Ile Cys Arg Cys Phe Thr Gly Tyr Thr Gly Glu Arg Cys 
    50                  55                  60                  


Glu His Leu Thr Leu Thr Ser Tyr Ala Val Asp Ser Tyr Glu Lys 
65                  70                  75                  


<210>  396
<211>  522
<212>  PRT
<213>  Homo Sapiens

<400>  396

Lys Glu Val Thr Leu Met Asp Thr Ser Lys Ala Gln Gly Glu Leu Gly 
1               5                   10                  15      


Trp Leu Leu Asp Pro Pro Lys Asp Gly Trp Ser Glu Gln Gln Gln Ile 
            20                  25                  30          


Leu Asn Gly Thr Pro Leu Tyr Met Tyr Gln Asp Cys Pro Met Gln Gly 
        35                  40                  45              


Arg Arg Asp Thr Asp His Trp Leu Arg Ser Asn Trp Ile Tyr Arg Gly 
    50                  55                  60                  


Glu Glu Ala Ser Arg Val His Val Glu Leu Gln Phe Thr Val Arg Asp 
65                  70                  75                  80  


Cys Lys Ser Phe Pro Gly Gly Ala Gly Pro Leu Gly Cys Lys Glu Thr 
                85                  90                  95      


Phe Asn Leu Leu Tyr Met Glu Ser Asp Gln Asp Val Gly Ile Gln Leu 
            100                 105                 110         


Arg Arg Pro Leu Phe Gln Lys Val Thr Thr Val Ala Ala Asp Gln Ser 
        115                 120                 125             


Phe Thr Ile Arg Asp Leu Ala Ser Gly Ser Val Lys Leu Asn Val Glu 
    130                 135                 140                 


Arg Cys Ser Leu Gly Arg Leu Thr Arg Arg Gly Leu Tyr Leu Ala Phe 
145                 150                 155                 160 


His Asn Pro Gly Ala Cys Val Ala Leu Val Ser Val Arg Val Phe Tyr 
                165                 170                 175     


Gln Arg Cys Pro Glu Thr Leu Asn Gly Leu Ala Gln Phe Pro Asp Thr 
            180                 185                 190         


Leu Pro Gly Pro Ala Gly Leu Val Glu Val Ala Gly Thr Cys Leu Pro 
        195                 200                 205             


His Ala Arg Ala Ser Pro Arg Pro Ser Gly Ala Pro Arg Met His Cys 
    210                 215                 220                 


Ser Pro Asp Gly Glu Trp Leu Val Pro Val Gly Arg Cys His Cys Glu 
225                 230                 235                 240 


Pro Gly Tyr Glu Glu Gly Gly Ser Gly Glu Ala Cys Val Ala Cys Pro 
                245                 250                 255     


Ser Gly Ser Tyr Arg Met Asp Met Asp Thr Pro His Cys Leu Thr Cys 
            260                 265                 270         


Pro Gln Gln Ser Thr Ala Glu Ser Glu Gly Ala Thr Ile Cys Thr Cys 
        275                 280                 285             


Glu Ser Gly His Tyr Arg Ala Pro Gly Glu Gly Pro Gln Val Ala Cys 
    290                 295                 300                 


Thr Gly Pro Pro Ser Ala Pro Arg Asn Leu Ser Phe Ser Ala Ser Gly 
305                 310                 315                 320 


Thr Gln Leu Ser Leu Arg Trp Glu Pro Pro Ala Asp Thr Gly Gly Arg 
                325                 330                 335     


Gln Asp Val Arg Tyr Ser Val Arg Cys Ser Gln Cys Gln Gly Thr Ala 
            340                 345                 350         


Gln Asp Gly Gly Pro Cys Gln Pro Cys Gly Val Gly Val His Phe Ser 
        355                 360                 365             


Pro Gly Ala Arg Gly Leu Thr Thr Pro Ala Val His Val Asn Gly Leu 
    370                 375                 380                 


Glu Pro Tyr Ala Asn Tyr Thr Phe Asn Val Glu Ala Gln Asn Gly Val 
385                 390                 395                 400 


Ser Gly Leu Gly Ser Ser Gly His Ala Ser Thr Ser Val Ser Ile Ser 
                405                 410                 415     


Met Gly His Ala Glu Ser Leu Ser Gly Leu Ser Leu Arg Leu Val Lys 
            420                 425                 430         


Lys Glu Pro Arg Gln Leu Glu Leu Thr Trp Ala Gly Ser Arg Pro Arg 
        435                 440                 445             


Ser Pro Gly Ala Asn Leu Thr Tyr Glu Leu His Val Leu Asn Gln Asp 
    450                 455                 460                 


Glu Glu Arg Tyr Gln Met Val Leu Glu Pro Arg Val Leu Leu Thr Glu 
465                 470                 475                 480 


Leu Gln Pro Asp Thr Thr Tyr Ile Val Arg Val Arg Met Leu Thr Pro 
                485                 490                 495     


Leu Gly Pro Gly Pro Phe Ser Pro Asp His Glu Phe Arg Thr Ser Pro 
            500                 505                 510         


Pro Val Ser Arg Gly Leu Thr Gly Gly Glu 
        515                 520         


<210>  397
<211>  532
<212>  PRT
<213>  Homo Sapiens

<400>  397

Glu Glu Val Ile Leu Leu Asp Ser Lys Ala Ser Gln Ala Glu Leu Gly 
1               5                   10                  15      


Trp Thr Ala Leu Pro Ser Asn Gly Trp Glu Glu Ile Ser Gly Val Asp 
            20                  25                  30          


Glu His Asp Arg Pro Ile Arg Thr Tyr Gln Val Cys Asn Val Leu Glu 
        35                  40                  45              


Pro Asn Gln Asp Asn Trp Leu Gln Thr Gly Trp Ile Ser Arg Gly Arg 
    50                  55                  60                  


Gly Gln Arg Ile Phe Val Glu Leu Gln Phe Thr Leu Arg Asp Cys Ser 
65                  70                  75                  80  


Ser Ile Pro Gly Ala Ala Gly Thr Cys Lys Glu Thr Phe Asn Val Tyr 
                85                  90                  95      


Tyr Leu Glu Thr Glu Ala Asp Leu Gly Arg Gly Arg Pro Arg Leu Gly 
            100                 105                 110         


Gly Ser Arg Pro Arg Lys Ile Asp Thr Ile Ala Ala Asp Glu Ser Phe 
        115                 120                 125             


Thr Gln Gly Asp Leu Gly Glu Arg Lys Met Lys Leu Asn Thr Glu Val 
    130                 135                 140                 


Arg Glu Ile Gly Pro Leu Ser Arg Arg Gly Phe His Leu Ala Phe Gln 
145                 150                 155                 160 


Asp Val Gly Ala Cys Val Ala Leu Val Ser Val Arg Val Tyr Tyr Lys 
                165                 170                 175     


Gln Cys Arg Ala Thr Val Arg Gly Leu Ala Thr Phe Pro Ala Thr Ala 
            180                 185                 190         


Ala Glu Ser Ala Phe Ser Thr Leu Val Glu Val Ala Gly Thr Cys Val 
        195                 200                 205             


Ala His Ser Glu Gly Glu Pro Gly Ser Pro Pro Arg Met His Cys Gly 
    210                 215                 220                 


Ala Asp Gly Glu Trp Leu Val Pro Val Gly Arg Cys Ser Cys Ser Ala 
225                 230                 235                 240 


Gly Phe Gln Glu Arg Gly Asp Phe Cys Glu Ala Cys Pro Pro Gly Phe 
                245                 250                 255     


Tyr Lys Val Ser Pro Arg Arg Pro Leu Cys Ser Pro Cys Pro Glu His 
            260                 265                 270         


Ser Arg Ala Leu Glu Asn Ala Ser Thr Phe Cys Val Cys Gln Asp Ser 
        275                 280                 285             


Tyr Ala Arg Ser Pro Thr Asp Pro Pro Ser Ala Ser Cys Thr Arg Pro 
    290                 295                 300                 


Pro Ser Ala Pro Arg Asp Leu Gln Tyr Ser Leu Ser Arg Ser Pro Leu 
305                 310                 315                 320 


Val Leu Arg Leu Arg Trp Leu Pro Pro Ala Asp Ser Gly Gly Arg Ser 
                325                 330                 335     


Asp Val Thr Tyr Ser Leu Leu Cys Leu Arg Cys Gly Arg Glu Gly Pro 
            340                 345                 350         


Ala Gly Ala Cys Glu Pro Cys Gly Pro Arg Val Ala Phe Leu Pro Arg 
        355                 360                 365             


Gln Ala Gly Leu Arg Glu Arg Ala Ala Thr Leu Leu His Leu Arg Pro 
    370                 375                 380                 


Gly Ala Arg Tyr Thr Val Arg Val Ala Ala Leu Asn Gly Val Ser Gly 
385                 390                 395                 400 


Pro Ala Ala Ala Ala Gly Thr Thr Tyr Ala Gln Val Thr Val Ser Thr 
                405                 410                 415     


Gly Pro Gly Ala Pro Trp Glu Glu Asp Glu Ile Arg Arg Asp Arg Val 
            420                 425                 430         


Glu Pro Gln Ser Val Ser Leu Ser Trp Arg Glu Pro Ile Pro Ala Gly 
        435                 440                 445             


Ala Pro Gly Ala Asn Asp Thr Glu Tyr Glu Ile Arg Tyr Tyr Glu Lys 
    450                 455                 460                 


Gly Gln Ser Glu Gln Thr Tyr Ser Met Val Lys Thr Gly Ala Pro Thr 
465                 470                 475                 480 


Val Thr Val Thr Asn Leu Lys Pro Ala Thr Arg Tyr Val Phe Gln Ile 
                485                 490                 495     


Arg Ala Ala Ser Pro Gly Pro Ser Trp Glu Ala Gln Ser Phe Asn Pro 
            500                 505                 510         


Ser Ile Glu Val Gln Thr Leu Gly Glu Ala Ala Ser Gly Ser Arg Asp 
        515                 520                 525             


Gln Ser Pro Ala 
    530         


<210>  398
<211>  514
<212>  PRT
<213>  Homo Sapiens

<400>  398

Ala Gln Gly Lys Glu Val Val Leu Leu Asp Phe Ala Ala Ala Gly Gly 
1               5                   10                  15      


Glu Leu Gly Trp Leu Thr His Pro Tyr Gly Lys Gly Trp Asp Leu Met 
            20                  25                  30          


Gln Asn Ile Met Asn Asp Met Pro Ile Tyr Met Tyr Ser Val Cys Asn 
        35                  40                  45              


Val Met Ser Gly Asp Gln Asp Asn Trp Leu Arg Thr Asn Trp Val Tyr 
    50                  55                  60                  


Arg Gly Glu Ala Glu Arg Ile Phe Ile Glu Leu Lys Phe Thr Val Arg 
65                  70                  75                  80  


Asp Cys Asn Ser Phe Pro Gly Gly Ala Ser Ser Cys Lys Glu Thr Phe 
                85                  90                  95      


Asn Leu Tyr Tyr Ala Glu Ser Asp Leu Asp Tyr Gly Thr Asn Phe Gln 
            100                 105                 110         


Lys Arg Leu Phe Thr Lys Ile Asp Thr Ile Ala Pro Asp Glu Ile Thr 
        115                 120                 125             


Val Ser Ser Asp Phe Glu Ala Arg His Val Lys Leu Asn Val Glu Glu 
    130                 135                 140                 


Arg Ser Val Gly Pro Leu Thr Arg Lys Gly Phe Tyr Leu Ala Phe Gln 
145                 150                 155                 160 


Asp Ile Gly Ala Cys Val Ala Leu Leu Ser Val Arg Val Tyr Tyr Lys 
                165                 170                 175     


Lys Cys Pro Glu Leu Leu Gln Gly Leu Ala His Phe Pro Glu Thr Ile 
            180                 185                 190         


Ala Gly Ser Asp Ala Pro Ser Leu Ala Thr Val Ala Gly Thr Cys Val 
        195                 200                 205             


Asp His Ala Val Val Pro Pro Gly Gly Glu Glu Pro Arg Met His Cys 
    210                 215                 220                 


Ala Val Asp Gly Glu Trp Leu Val Pro Ile Gly Gln Cys Leu Cys Gln 
225                 230                 235                 240 


Ala Gly Tyr Glu Lys Val Glu Asp Ala Cys Gln Ala Cys Ser Pro Gly 
                245                 250                 255     


Phe Phe Lys Phe Glu Ala Ser Glu Ser Pro Cys Leu Glu Cys Pro Glu 
            260                 265                 270         


His Thr Leu Pro Ser Pro Glu Gly Ala Thr Ser Cys Glu Cys Glu Glu 
        275                 280                 285             


Gly Phe Phe Arg Ala Pro Gln Asp Pro Ala Ser Met Pro Cys Thr Arg 
    290                 295                 300                 


Pro Pro Ser Ala Pro His Tyr Leu Thr Ala Val Gly Met Gly Ala Lys 
305                 310                 315                 320 


Val Glu Leu Arg Trp Thr Pro Pro Gln Asp Ser Gly Gly Arg Glu Asp 
                325                 330                 335     


Ile Val Tyr Ser Val Thr Cys Glu Gln Cys Trp Pro Glu Ser Gly Glu 
            340                 345                 350         


Cys Gly Pro Cys Glu Ala Ser Val Arg Tyr Ser Glu Pro Pro His Gly 
        355                 360                 365             


Leu Thr Arg Thr Ser Val Thr Val Ser Asp Leu Glu Pro His Met Asn 
    370                 375                 380                 


Tyr Thr Phe Thr Val Glu Ala Arg Asn Gly Val Ser Gly Leu Val Thr 
385                 390                 395                 400 


Ser Arg Ser Phe Arg Thr Ala Ser Val Ser Ile Asn Gln Thr Glu Pro 
                405                 410                 415     


Pro Lys Val Arg Leu Glu Gly Arg Ser Thr Thr Ser Leu Ser Val Ser 
            420                 425                 430         


Trp Ser Ile Pro Pro Pro Gln Gln Ser Arg Val Trp Lys Tyr Glu Val 
        435                 440                 445             


Thr Tyr Arg Lys Lys Gly Asp Ser Asn Ser Tyr Asn Val Arg Arg Thr 
    450                 455                 460                 


Glu Gly Phe Ser Val Thr Leu Asp Asp Leu Ala Pro Asp Thr Thr Tyr 
465                 470                 475                 480 


Leu Val Gln Val Gln Ala Leu Thr Gln Glu Gly Gln Gly Ala Gly Ser 
                485                 490                 495     


Lys Val His Glu Phe Gln Thr Leu Ser Pro Glu Gly Ser Gly Asn Leu 
            500                 505                 510         


Ala Val 
        


<210>  399
<211>  521
<212>  PRT
<213>  Homo Sapiens

<400>  399

Glu Leu Ile Pro Gln Pro Ser Asn Glu Val Asn Leu Leu Asp Ser Lys 
1               5                   10                  15      


Thr Ile Gln Gly Glu Leu Gly Trp Ile Ser Tyr Pro Ser His Gly Trp 
            20                  25                  30          


Glu Glu Ile Ser Gly Val Asp Glu His Tyr Thr Pro Ile Arg Thr Tyr 
        35                  40                  45              


Gln Val Cys Asn Val Met Asp His Ser Gln Asn Asn Trp Leu Arg Thr 
    50                  55                  60                  


Asn Trp Val Pro Arg Asn Ser Ala Gln Lys Ile Tyr Val Glu Leu Lys 
65                  70                  75                  80  


Phe Thr Leu Arg Asp Cys Asn Ser Ile Pro Leu Val Leu Gly Thr Cys 
                85                  90                  95      


Lys Glu Thr Phe Asn Leu Tyr Tyr Met Glu Ser Asp Asp Asp His Gly 
            100                 105                 110         


Val Lys Phe Arg Glu His Gln Phe Thr Lys Ile Asp Thr Ile Ala Ala 
        115                 120                 125             


Asp Glu Ser Phe Thr Gln Met Asp Leu Gly Asp Arg Ile Leu Lys Leu 
    130                 135                 140                 


Asn Thr Glu Ile Arg Glu Val Gly Pro Val Asn Lys Lys Gly Phe Tyr 
145                 150                 155                 160 


Leu Ala Phe Gln Asp Val Gly Ala Cys Val Ala Leu Val Ser Val Arg 
                165                 170                 175     


Val Tyr Phe Lys Lys Cys Pro Phe Thr Val Lys Asn Leu Ala Met Phe 
            180                 185                 190         


Pro Asp Thr Val Pro Met Asp Ser Gln Ser Leu Val Glu Val Arg Gly 
        195                 200                 205             


Ser Cys Val Asn Asn Ser Lys Glu Glu Asp Pro Pro Arg Met Tyr Cys 
    210                 215                 220                 


Ser Thr Glu Gly Glu Trp Leu Val Pro Ile Gly Lys Cys Ser Cys Asn 
225                 230                 235                 240 


Ala Gly Tyr Glu Glu Arg Gly Phe Met Cys Gln Ala Cys Arg Pro Gly 
                245                 250                 255     


Phe Tyr Lys Ala Leu Asp Gly Asn Met Lys Cys Ala Lys Cys Pro Pro 
            260                 265                 270         


His Ser Ser Thr Gln Glu Asp Gly Ser Met Asn Cys Arg Cys Glu Asn 
        275                 280                 285             


Asn Tyr Phe Arg Ala Asp Lys Asp Pro Pro Ser Met Ala Cys Thr Arg 
    290                 295                 300                 


Pro Pro Ser Ser Pro Arg Asn Val Ile Ser Asn Ile Asn Glu Thr Ser 
305                 310                 315                 320 


Val Ile Leu Asp Trp Ser Trp Pro Leu Asp Thr Gly Gly Arg Lys Asp 
                325                 330                 335     


Val Thr Phe Asn Ile Ile Cys Lys Lys Cys Gly Trp Asn Ile Lys Gln 
            340                 345                 350         


Cys Glu Pro Cys Ser Pro Asn Val Arg Phe Leu Pro Arg Gln Phe Gly 
        355                 360                 365             


Leu Thr Asn Thr Thr Val Thr Val Thr Asp Leu Leu Ala His Thr Asn 
    370                 375                 380                 


Tyr Thr Phe Glu Ile Asp Ala Val Asn Gly Val Ser Glu Leu Ser Ser 
385                 390                 395                 400 


Pro Pro Arg Gln Phe Ala Ala Val Ser Ile Thr Thr Asn Gln Ala Ala 
                405                 410                 415     


Pro Ser Pro Val Leu Thr Ile Lys Lys Asp Arg Thr Ser Arg Asn Ser 
            420                 425                 430         


Ile Ser Leu Ser Trp Gln Glu Pro Glu His Pro Asn Gly Ile Ile Leu 
        435                 440                 445             


Asp Tyr Glu Val Lys Tyr Tyr Glu Lys Gln Glu Gln Glu Thr Ser Tyr 
    450                 455                 460                 


Thr Ile Leu Arg Ala Arg Gly Thr Asn Val Thr Ile Ser Ser Leu Lys 
465                 470                 475                 480 


Pro Asp Thr Ile Tyr Val Phe Gln Ile Arg Ala Arg Thr Ala Ala Gly 
                485                 490                 495     


Tyr Gly Thr Asn Ser Arg Lys Phe Glu Phe Glu Thr Ser Pro Asp Ser 
            500                 505                 510         


Phe Ser Ile Ser Gly Glu Ser Ser Gln 
        515                 520     


<210>  400
<211>  528
<212>  PRT
<213>  Homo Sapiens

<400>  400

Val Thr Gly Ser Arg Val Tyr Pro Ala Asn Glu Val Thr Leu Leu Asp 
1               5                   10                  15      


Ser Arg Ser Val Gln Gly Glu Leu Gly Trp Ile Ala Ser Pro Leu Glu 
            20                  25                  30          


Gly Gly Trp Glu Glu Val Ser Ile Met Asp Glu Lys Asn Thr Pro Ile 
        35                  40                  45              


Arg Thr Tyr Gln Val Cys Asn Val Met Glu Pro Ser Gln Asn Asn Trp 
    50                  55                  60                  


Leu Arg Thr Asp Trp Ile Thr Arg Glu Gly Ala Gln Arg Val Tyr Ile 
65                  70                  75                  80  


Glu Ile Lys Phe Thr Leu Arg Asp Cys Asn Ser Leu Pro Gly Val Met 
                85                  90                  95      


Gly Thr Cys Lys Glu Thr Phe Asn Leu Tyr Tyr Tyr Glu Ser Asp Asn 
            100                 105                 110         


Asp Lys Glu Arg Phe Ile Arg Glu Asn Gln Phe Val Lys Ile Asp Thr 
        115                 120                 125             


Ile Ala Ala Asp Glu Ser Phe Thr Gln Val Asp Ile Gly Asp Arg Ile 
    130                 135                 140                 


Met Lys Leu Asn Thr Glu Ile Arg Asp Val Gly Pro Leu Ser Lys Lys 
145                 150                 155                 160 


Gly Phe Tyr Leu Ala Phe Gln Asp Val Gly Ala Cys Ile Ala Leu Val 
                165                 170                 175     


Ser Val Arg Val Phe Tyr Lys Lys Cys Pro Leu Thr Val Arg Asn Leu 
            180                 185                 190         


Ala Gln Phe Pro Asp Thr Ile Thr Gly Ala Asp Thr Ser Ser Leu Val 
        195                 200                 205             


Glu Val Arg Gly Ser Cys Val Asn Asn Ser Glu Glu Lys Asp Val Pro 
    210                 215                 220                 


Lys Met Tyr Cys Gly Ala Asp Gly Glu Trp Leu Val Pro Ile Gly Asn 
225                 230                 235                 240 


Cys Leu Cys Asn Ala Gly His Glu Glu Arg Ser Gly Glu Cys Gln Ala 
                245                 250                 255     


Cys Lys Ile Gly Tyr Tyr Lys Ala Leu Ser Thr Asp Ala Thr Cys Ala 
            260                 265                 270         


Lys Cys Pro Pro His Ser Tyr Ser Val Trp Glu Gly Ala Thr Ser Cys 
        275                 280                 285             


Thr Cys Asp Arg Gly Phe Phe Arg Ala Asp Asn Asp Ala Ala Ser Met 
    290                 295                 300                 


Pro Cys Thr Arg Pro Pro Ser Ala Pro Leu Asn Leu Ile Ser Asn Val 
305                 310                 315                 320 


Asn Glu Thr Ser Val Asn Leu Glu Trp Ser Ser Pro Gln Asn Thr Gly 
                325                 330                 335     


Gly Arg Gln Asp Ile Ser Tyr Asn Val Val Cys Lys Lys Cys Gly Ala 
            340                 345                 350         


Gly Asp Pro Ser Lys Cys Arg Pro Cys Gly Ser Gly Val His Tyr Thr 
        355                 360                 365             


Pro Gln Gln Asn Gly Leu Lys Thr Thr Lys Val Ser Ile Thr Asp Leu 
    370                 375                 380                 


Leu Ala His Thr Asn Tyr Thr Phe Glu Ile Trp Ala Val Asn Gly Val 
385                 390                 395                 400 


Ser Lys Tyr Asn Pro Asn Pro Asp Gln Ser Val Ser Val Thr Val Thr 
                405                 410                 415     


Thr Asn Gln Ala Ala Pro Ser Ser Ile Ala Leu Val Gln Ala Lys Glu 
            420                 425                 430         


Val Thr Arg Tyr Ser Val Ala Leu Ala Trp Leu Glu Pro Asp Arg Pro 
        435                 440                 445             


Asn Gly Val Ile Leu Glu Tyr Glu Val Lys Tyr Tyr Glu Lys Asp Gln 
    450                 455                 460                 


Asn Glu Arg Ser Tyr Arg Ile Val Arg Thr Ala Ala Arg Asn Thr Asp 
465                 470                 475                 480 


Ile Lys Gly Leu Asn Pro Leu Thr Ser Tyr Val Phe His Val Arg Ala 
                485                 490                 495     


Arg Thr Ala Ala Gly Tyr Gly Asp Phe Ser Glu Pro Leu Glu Val Thr 
            500                 505                 510         


Thr Asn Thr Val Pro Ser Arg Ile Ile Gly Asp Gly Ala Asn Ser Thr 
        515                 520                 525             


<210>  401
<211>  550
<212>  PRT
<213>  Homo Sapiens

<400>  401

Pro Ala Ser Leu Ala Gly Cys Tyr Ser Ala Pro Arg Arg Ala Pro Leu 
1               5                   10                  15      


Trp Thr Cys Leu Leu Leu Cys Ala Ala Leu Arg Thr Leu Leu Ala Ser 
            20                  25                  30          


Pro Ser Asn Glu Val Asn Leu Leu Asp Ser Arg Thr Val Met Gly Asp 
        35                  40                  45              


Leu Gly Trp Ile Ala Phe Pro Lys Asn Gly Trp Glu Glu Ile Gly Glu 
    50                  55                  60                  


Val Asp Glu Asn Tyr Ala Pro Ile His Thr Tyr Gln Val Cys Lys Val 
65                  70                  75                  80  


Met Glu Gln Asn Gln Asn Asn Trp Leu Leu Thr Ser Trp Ile Ser Asn 
                85                  90                  95      


Glu Gly Ala Ser Arg Ile Phe Ile Glu Leu Lys Phe Thr Leu Arg Asp 
            100                 105                 110         


Cys Asn Ser Leu Pro Gly Gly Leu Gly Thr Cys Lys Glu Thr Phe Asn 
        115                 120                 125             


Met Tyr Tyr Phe Glu Ser Asp Asp Gln Asn Gly Arg Asn Ile Lys Glu 
    130                 135                 140                 


Asn Gln Tyr Ile Lys Ile Asp Thr Ile Ala Ala Asp Glu Ser Phe Thr 
145                 150                 155                 160 


Glu Leu Asp Leu Gly Asp Arg Val Met Lys Leu Asn Thr Glu Val Arg 
                165                 170                 175     


Asp Val Gly Pro Leu Ser Lys Lys Gly Phe Tyr Leu Ala Phe Gln Asp 
            180                 185                 190         


Val Gly Ala Cys Ile Ala Leu Val Ser Val Arg Val Tyr Tyr Lys Lys 
        195                 200                 205             


Cys Pro Ser Val Val Arg His Leu Ala Val Phe Pro Asp Thr Ile Thr 
    210                 215                 220                 


Gly Ala Asp Ser Ser Gln Leu Leu Glu Val Ser Gly Ser Cys Val Asn 
225                 230                 235                 240 


His Ser Val Thr Asp Glu Pro Pro Lys Met His Cys Ser Ala Glu Gly 
                245                 250                 255     


Glu Trp Leu Val Pro Ile Gly Lys Cys Met Cys Lys Ala Gly Tyr Glu 
            260                 265                 270         


Glu Lys Asn Gly Thr Cys Gln Val Cys Arg Pro Gly Phe Phe Lys Ala 
        275                 280                 285             


Ser Pro His Ile Gln Ser Cys Gly Lys Cys Pro Pro His Ser Tyr Thr 
    290                 295                 300                 


His Glu Glu Ala Ser Thr Ser Cys Val Cys Glu Lys Asp Tyr Phe Arg 
305                 310                 315                 320 


Arg Glu Ser Asp Pro Pro Thr Met Ala Cys Thr Arg Pro Pro Ser Ala 
                325                 330                 335     


Pro Arg Asn Ala Ile Ser Asn Val Asn Glu Thr Ser Val Phe Leu Glu 
            340                 345                 350         


Trp Ile Pro Pro Ala Asp Thr Gly Gly Arg Lys Asp Val Ser Tyr Tyr 
        355                 360                 365             


Ile Ala Cys Lys Lys Cys Asn Ser His Ala Gly Val Cys Glu Glu Cys 
    370                 375                 380                 


Gly Gly His Val Arg Tyr Leu Pro Arg Gln Ser Gly Leu Lys Asn Thr 
385                 390                 395                 400 


Ser Val Met Met Val Asp Leu Leu Ala His Thr Asn Tyr Thr Phe Glu 
                405                 410                 415     


Ile Glu Ala Val Asn Gly Val Ser Asp Leu Ser Pro Gly Ala Arg Gln 
            420                 425                 430         


Tyr Val Ser Val Asn Val Thr Thr Asn Gln Ala Ala Pro Ser Pro Val 
        435                 440                 445             


Thr Asn Val Lys Lys Gly Lys Ile Ala Lys Asn Ser Ile Ser Leu Ser 
    450                 455                 460                 


Trp Gln Glu Pro Asp Arg Pro Asn Gly Ile Ile Leu Glu Tyr Glu Ile 
465                 470                 475                 480 


Lys Tyr Phe Glu Lys Asp Gln Glu Thr Ser Tyr Thr Ile Ile Lys Ser 
                485                 490                 495     


Lys Glu Thr Thr Ile Thr Ala Glu Gly Leu Lys Pro Ala Ser Val Tyr 
            500                 505                 510         


Val Phe Gln Ile Arg Ala Arg Thr Ala Ala Gly Tyr Gly Val Phe Ser 
        515                 520                 525             


Arg Arg Phe Glu Phe Glu Thr Thr Pro Val Ser Val Ala Ala Ser Ser 
    530                 535                 540                 


Asp Gln Ser Gln Ile Pro 
545                 550 


<210>  402
<211>  36
<212>  PRT
<213>  Homo Sapiens

<400>  402

Met Lys Asp Ser Pro Phe Gln Val Thr Lys Leu Tyr Trp Leu Asn Glu 
1               5                   10                  15      


Lys Trp Asp Phe Ile Ala Ser Ala Ser Asp Met Ala Ala Glu Gln Gly 
            20                  25                  30          


Gln Ile Leu Val 
        35      


<210>  403
<211>  528
<212>  PRT
<213>  Homo Sapiens

<400>  403

Gln Ala Ala Lys Glu Val Leu Leu Leu Asp Ser Lys Ala Gln Gln Thr 
1               5                   10                  15      


Glu Leu Glu Trp Ile Ser Ser Pro Pro Asn Gly Trp Glu Glu Ile Ser 
            20                  25                  30          


Gly Leu Asp Glu Asn Tyr Thr Pro Ile Arg Thr Tyr Gln Val Cys Gln 
        35                  40                  45              


Val Met Glu Pro Asn Gln Asn Asn Trp Leu Arg Thr Asn Trp Ile Ser 
    50                  55                  60                  


Lys Gly Asn Ala Gln Arg Ile Phe Val Glu Leu Lys Phe Thr Leu Arg 
65                  70                  75                  80  


Asp Cys Asn Ser Leu Pro Gly Val Leu Gly Thr Cys Lys Glu Thr Phe 
                85                  90                  95      


Asn Leu Tyr Tyr Tyr Glu Thr Asp Tyr Asp Thr Gly Arg Asn Ile Arg 
            100                 105                 110         


Glu Asn Leu Tyr Val Lys Ile Asp Thr Ile Ala Ala Asp Glu Ser Phe 
        115                 120                 125             


Thr Gln Gly Asp Leu Gly Glu Arg Lys Met Lys Leu Asn Thr Glu Val 
    130                 135                 140                 


Arg Glu Ile Gly Pro Leu Ser Lys Lys Gly Phe Tyr Leu Ala Phe Gln 
145                 150                 155                 160 


Asp Val Gly Ala Cys Ile Ala Leu Val Ser Val Lys Val Tyr Tyr Lys 
                165                 170                 175     


Lys Cys Trp Ser Ile Ile Glu Asn Leu Ala Ile Phe Pro Asp Thr Val 
            180                 185                 190         


Thr Gly Ser Glu Phe Ser Ser Leu Val Glu Val Arg Gly Thr Cys Val 
        195                 200                 205             


Ser Ser Ala Glu Glu Glu Ala Glu Asn Ala Pro Arg Met His Cys Ser 
    210                 215                 220                 


Ala Glu Gly Glu Trp Leu Val Pro Ile Gly Lys Cys Ile Cys Lys Ala 
225                 230                 235                 240 


Gly Tyr Gln Gln Lys Gly Asp Thr Cys Glu Pro Cys Gly Arg Gly Phe 
                245                 250                 255     


Tyr Lys Ser Ser Ser Gln Asp Leu Gln Cys Ser Arg Cys Pro Thr His 
            260                 265                 270         


Ser Phe Ser Asp Lys Glu Gly Ser Ser Arg Cys Glu Cys Glu Asp Gly 
        275                 280                 285             


Tyr Tyr Arg Ala Pro Ser Asp Pro Pro Tyr Val Ala Cys Thr Arg Pro 
    290                 295                 300                 


Pro Ser Ala Pro Gln Asn Leu Ile Phe Asn Ile Asn Gln Thr Thr Val 
305                 310                 315                 320 


Ser Leu Glu Trp Ser Pro Pro Ala Asp Asn Gly Gly Arg Asn Asp Val 
                325                 330                 335     


Thr Tyr Arg Ile Leu Cys Lys Arg Cys Ser Trp Glu Gln Gly Glu Cys 
            340                 345                 350         


Val Pro Cys Gly Ser Asn Ile Gly Tyr Met Pro Gln Gln Thr Gly Leu 
        355                 360                 365             


Glu Asp Asn Tyr Val Thr Val Met Asp Leu Leu Ala His Ala Asn Tyr 
    370                 375                 380                 


Thr Phe Glu Val Glu Ala Val Asn Gly Val Ser Asp Leu Ser Arg Ser 
385                 390                 395                 400 


Gln Arg Leu Phe Ala Ala Val Ser Ile Thr Thr Gly Gln Ala Ala Pro 
                405                 410                 415     


Ser Gln Val Ser Gly Val Met Lys Glu Arg Val Leu Gln Arg Ser Val 
            420                 425                 430         


Glu Leu Ser Trp Gln Glu Pro Glu His Pro Asn Gly Val Ile Thr Glu 
        435                 440                 445             


Tyr Glu Ile Lys Tyr Tyr Glu Lys Asp Gln Arg Glu Arg Thr Tyr Ser 
    450                 455                 460                 


Thr Val Lys Thr Lys Ser Thr Ser Ala Ser Ile Asn Asn Leu Lys Pro 
465                 470                 475                 480 


Gly Thr Val Tyr Val Phe Gln Ile Arg Ala Phe Thr Ala Ala Gly Tyr 
                485                 490                 495     


Gly Asn Tyr Ser Pro Arg Leu Asp Val Ala Thr Leu Glu Glu Ala Thr 
            500                 505                 510         


Gly Lys Met Phe Glu Ala Thr Ala Val Ser Ser Glu Gln Asn Pro Val 
        515                 520                 525             


<210>  404
<211>  515
<212>  PRT
<213>  Homo Sapiens

<400>  404

Ala Arg Gly Glu Val Asn Leu Leu Asp Thr Ser Thr Ile His Gly Asp 
1               5                   10                  15      


Trp Gly Trp Leu Thr Tyr Pro Ala His Gly Trp Asp Ser Ile Asn Glu 
            20                  25                  30          


Val Asp Glu Ser Phe Gln Pro Ile His Thr Tyr Gln Val Cys Asn Val 
        35                  40                  45              


Met Ser Pro Asn Gln Asn Asn Trp Leu Arg Thr Ser Trp Val Pro Arg 
    50                  55                  60                  


Asp Gly Ala Arg Arg Val Tyr Ala Glu Ile Lys Phe Thr Leu Arg Asp 
65                  70                  75                  80  


Cys Asn Ser Met Pro Gly Val Leu Gly Thr Cys Lys Glu Thr Phe Asn 
                85                  90                  95      


Leu Tyr Tyr Leu Glu Ser Asp Arg Asp Leu Gly Ala Ser Thr Gln Glu 
            100                 105                 110         


Ser Gln Phe Leu Lys Ile Asp Thr Ile Ala Ala Asp Glu Ser Phe Thr 
        115                 120                 125             


Gly Ala Asp Leu Gly Val Arg Arg Leu Lys Leu Asn Thr Glu Val Arg 
    130                 135                 140                 


Ser Val Gly Pro Leu Ser Lys Arg Gly Phe Tyr Leu Ala Phe Gln Asp 
145                 150                 155                 160 


Ile Gly Ala Cys Leu Ala Ile Leu Ser Leu Arg Ile Tyr Tyr Lys Lys 
                165                 170                 175     


Cys Pro Ala Met Val Arg Asn Leu Ala Ala Phe Ser Glu Ala Val Thr 
            180                 185                 190         


Gly Ala Asp Ser Ser Ser Leu Val Glu Val Arg Gly Gln Cys Val Arg 
        195                 200                 205             


His Ser Glu Glu Arg Asp Thr Pro Lys Met Tyr Cys Ser Ala Glu Gly 
    210                 215                 220                 


Glu Trp Leu Val Pro Ile Gly Lys Cys Val Cys Ser Ala Gly Tyr Glu 
225                 230                 235                 240 


Glu Arg Arg Asp Ala Cys Val Ala Cys Glu Leu Gly Phe Tyr Lys Ser 
                245                 250                 255     


Ala Pro Gly Asp Gln Leu Cys Ala Arg Cys Pro Pro His Ser His Ser 
            260                 265                 270         


Ala Ala Pro Ala Ala Gln Ala Cys His Cys Asp Leu Ser Tyr Tyr Arg 
        275                 280                 285             


Ala Ala Leu Asp Pro Pro Ser Ser Ala Cys Thr Arg Pro Pro Ser Ala 
    290                 295                 300                 


Pro Val Asn Leu Ile Ser Ser Val Asn Gly Thr Ser Val Thr Leu Glu 
305                 310                 315                 320 


Trp Ala Pro Pro Leu Asp Pro Gly Gly Arg Ser Asp Ile Thr Tyr Asn 
                325                 330                 335     


Ala Val Cys Arg Arg Cys Pro Trp Ala Leu Ser Arg Cys Glu Ala Cys 
            340                 345                 350         


Gly Ser Gly Thr Arg Phe Val Pro Gln Gln Thr Ser Leu Val Gln Ala 
        355                 360                 365             


Ser Leu Leu Val Ala Asn Leu Leu Ala His Met Asn Tyr Ser Phe Trp 
    370                 375                 380                 


Ile Glu Ala Val Asn Gly Val Ser Asp Leu Ser Pro Glu Pro Arg Arg 
385                 390                 395                 400 


Ala Ala Val Val Asn Ile Thr Thr Asn Gln Ala Ala Pro Ser Gln Val 
                405                 410                 415     


Val Val Ile Arg Gln Glu Arg Ala Gly Gln Thr Ser Val Ser Leu Leu 
            420                 425                 430         


Trp Gln Glu Pro Glu Gln Pro Asn Gly Ile Ile Leu Glu Tyr Glu Ile 
        435                 440                 445             


Lys Tyr Tyr Glu Lys Asp Lys Glu Met Gln Ser Tyr Ser Thr Leu Lys 
    450                 455                 460                 


Ala Val Thr Thr Arg Ala Thr Val Ser Gly Leu Lys Pro Gly Thr Arg 
465                 470                 475                 480 


Tyr Val Phe Gln Val Arg Ala Arg Thr Ser Ala Gly Cys Gly Arg Phe 
                485                 490                 495     


Ser Gln Ala Met Glu Val Glu Thr Gly Lys Pro Arg Pro Arg Tyr Asp 
            500                 505                 510         


Thr Arg Thr 
        515 


<210>  405
<211>  523
<212>  PRT
<213>  Homo Sapiens

<400>  405

Met Glu Glu Thr Leu Met Asp Thr Arg Thr Ala Thr Ala Glu Leu Gly 
1               5                   10                  15      


Trp Thr Ala Asn Pro Ala Ser Gly Trp Glu Glu Val Ser Gly Tyr Asp 
            20                  25                  30          


Glu Asn Leu Asn Thr Ile Arg Thr Tyr Gln Val Cys Asn Val Phe Glu 
        35                  40                  45              


Pro Asn Gln Asn Asn Trp Leu Leu Thr Thr Phe Ile Asn Arg Arg Gly 
    50                  55                  60                  


Ala His Arg Ile Tyr Thr Glu Met Arg Phe Thr Val Arg Asp Cys Ser 
65                  70                  75                  80  


Ser Leu Pro Asn Val Pro Gly Ser Cys Lys Glu Thr Phe Asn Leu Tyr 
                85                  90                  95      


Tyr Tyr Glu Thr Asp Ser Val Ile Ala Thr Lys Lys Ser Ala Phe Trp 
            100                 105                 110         


Ser Glu Ala Pro Tyr Leu Lys Val Asp Thr Ile Ala Ala Asp Glu Ser 
        115                 120                 125             


Phe Ser Gln Val Asp Phe Gly Gly Arg Leu Met Lys Val Asn Thr Glu 
    130                 135                 140                 


Val Arg Ser Phe Gly Pro Leu Thr Arg Asn Gly Phe Tyr Leu Ala Phe 
145                 150                 155                 160 


Gln Asp Tyr Gly Ala Cys Met Ser Leu Leu Ser Val Arg Val Phe Phe 
                165                 170                 175     


Lys Lys Cys Pro Ser Ile Val Gln Asn Phe Ala Val Phe Pro Glu Thr 
            180                 185                 190         


Met Thr Gly Ala Glu Ser Thr Ser Leu Val Ile Ala Arg Gly Thr Cys 
        195                 200                 205             


Ile Pro Asn Ala Glu Glu Val Asp Val Pro Ile Lys Leu Tyr Cys Asn 
    210                 215                 220                 


Gly Asp Gly Glu Trp Met Val Pro Ile Gly Arg Cys Thr Cys Lys Pro 
225                 230                 235                 240 


Gly Tyr Glu Pro Glu Asn Ser Val Ala Cys Lys Ala Cys Pro Ala Gly 
                245                 250                 255     


Thr Phe Lys Ala Ser Gln Glu Ala Glu Gly Cys Ser His Cys Pro Ser 
            260                 265                 270         


Asn Ser Arg Ser Pro Ala Glu Ala Ser Pro Ile Cys Thr Cys Arg Thr 
        275                 280                 285             


Gly Tyr Tyr Arg Ala Asp Phe Asp Pro Pro Glu Val Ala Cys Thr Ser 
    290                 295                 300                 


Val Pro Ser Gly Pro Arg Asn Val Ile Ser Ile Val Asn Glu Thr Ser 
305                 310                 315                 320 


Ile Ile Leu Glu Trp His Pro Pro Arg Glu Thr Gly Gly Arg Asp Asp 
                325                 330                 335     


Val Thr Tyr Asn Ile Ile Cys Lys Lys Cys Arg Ala Asp Arg Arg Ser 
            340                 345                 350         


Cys Ser Arg Cys Asp Asp Asn Val Glu Phe Val Pro Arg Gln Leu Gly 
        355                 360                 365             


Leu Thr Glu Cys Arg Val Ser Ile Ser Ser Leu Trp Ala His Thr Pro 
    370                 375                 380                 


Tyr Thr Phe Asp Ile Gln Ala Ile Asn Gly Val Ser Ser Lys Ser Pro 
385                 390                 395                 400 


Phe Pro Pro Gln His Val Ser Val Asn Ile Thr Thr Asn Gln Ala Ala 
                405                 410                 415     


Pro Ser Thr Val Pro Ile Met His Gln Val Ser Ala Thr Met Arg Ser 
            420                 425                 430         


Ile Thr Leu Ser Trp Pro Gln Pro Glu Gln Pro Asn Gly Ile Ile Leu 
        435                 440                 445             


Asp Tyr Glu Ile Arg Tyr Tyr Glu Lys Glu His Asn Glu Phe Asn Ser 
    450                 455                 460                 


Ser Met Ala Arg Ser Gln Thr Asn Thr Ala Arg Ile Asp Gly Leu Arg 
465                 470                 475                 480 


Pro Gly Met Val Tyr Val Val Gln Val Arg Ala Arg Thr Val Ala Gly 
                485                 490                 495     


Tyr Gly Lys Phe Ser Gly Lys Met Cys Phe Gln Thr Leu Thr Asp Asp 
            500                 505                 510         


Asp Tyr Lys Ser Glu Leu Arg Glu Gln Leu Pro 
        515                 520             


<210>  406
<211>  525
<212>  PRT
<213>  Homo Sapiens

<400>  406

Val Glu Glu Thr Leu Met Asp Ser Thr Thr Ala Thr Ala Glu Leu Gly 
1               5                   10                  15      


Trp Met Val His Pro Pro Ser Gly Trp Glu Glu Val Ser Gly Tyr Asp 
            20                  25                  30          


Glu Asn Met Asn Thr Ile Arg Thr Tyr Gln Val Cys Asn Val Phe Glu 
        35                  40                  45              


Ser Ser Gln Asn Asn Trp Leu Arg Thr Lys Phe Ile Arg Arg Arg Gly 
    50                  55                  60                  


Ala His Arg Ile His Val Glu Met Lys Phe Ser Val Arg Asp Cys Ser 
65                  70                  75                  80  


Ser Ile Pro Ser Val Pro Gly Ser Cys Lys Glu Thr Phe Asn Leu Tyr 
                85                  90                  95      


Tyr Tyr Glu Ala Asp Phe Asp Ser Ala Thr Lys Thr Phe Pro Asn Trp 
            100                 105                 110         


Met Glu Asn Pro Trp Val Lys Val Asp Thr Ile Ala Ala Asp Glu Ser 
        115                 120                 125             


Phe Ser Gln Val Asp Leu Gly Gly Arg Val Met Lys Ile Asn Thr Glu 
    130                 135                 140                 


Val Arg Ser Phe Gly Pro Val Ser Arg Ser Gly Phe Tyr Leu Ala Phe 
145                 150                 155                 160 


Gln Asp Tyr Gly Gly Cys Met Ser Leu Ile Ala Val Arg Val Phe Tyr 
                165                 170                 175     


Arg Lys Cys Pro Arg Ile Ile Gln Asn Gly Ala Ile Phe Gln Glu Thr 
            180                 185                 190         


Leu Ser Gly Ala Glu Ser Thr Ser Leu Val Ala Ala Arg Gly Ser Cys 
        195                 200                 205             


Ile Ala Asn Ala Glu Glu Val Asp Val Pro Ile Lys Leu Tyr Cys Asn 
    210                 215                 220                 


Gly Asp Gly Glu Trp Leu Val Pro Ile Gly Arg Cys Met Cys Lys Ala 
225                 230                 235                 240 


Gly Phe Glu Ala Val Glu Asn Gly Thr Val Cys Arg Gly Cys Pro Ser 
                245                 250                 255     


Gly Thr Phe Lys Ala Asn Gln Gly Asp Glu Ala Cys Thr His Cys Pro 
            260                 265                 270         


Ile Asn Ser Arg Thr Thr Ser Glu Gly Ala Thr Asn Cys Val Cys Arg 
        275                 280                 285             


Asn Gly Tyr Tyr Arg Ala Asp Leu Asp Pro Leu Asp Met Pro Cys Thr 
    290                 295                 300                 


Thr Ile Pro Ser Ala Pro Gln Ala Val Ile Ser Ser Val Asn Glu Thr 
305                 310                 315                 320 


Ser Leu Met Leu Glu Trp Thr Pro Pro Arg Asp Ser Gly Gly Arg Glu 
                325                 330                 335     


Asp Leu Val Tyr Asn Ile Ile Cys Lys Ser Cys Gly Ser Gly Arg Gly 
            340                 345                 350         


Ala Cys Thr Arg Cys Gly Asp Asn Val Gln Tyr Ala Pro Arg Gln Leu 
        355                 360                 365             


Gly Leu Thr Glu Pro Arg Ile Tyr Ile Ser Asp Leu Leu Ala His Thr 
    370                 375                 380                 


Gln Tyr Thr Phe Glu Ile Gln Ala Val Asn Gly Val Thr Asp Gln Ser 
385                 390                 395                 400 


Pro Phe Ser Pro Gln Phe Ala Ser Val Asn Ile Thr Thr Asn Gln Ala 
                405                 410                 415     


Ala Pro Ser Ala Val Ser Ile Met His Gln Val Ser Arg Thr Val Asp 
            420                 425                 430         


Ser Ile Thr Leu Ser Trp Ser Gln Pro Asp Gln Pro Asn Gly Val Ile 
        435                 440                 445             


Leu Asp Tyr Glu Leu Gln Tyr Tyr Glu Lys Glu Leu Ser Glu Tyr Asn 
    450                 455                 460                 


Ala Thr Ala Ile Lys Ser Pro Thr Asn Thr Val Thr Val Gln Gly Leu 
465                 470                 475                 480 


Lys Ala Gly Ala Ile Tyr Val Phe Gln Val Arg Ala Arg Thr Val Ala 
                485                 490                 495     


Gly Tyr Gly Arg Tyr Ser Gly Lys Met Tyr Phe Gln Thr Met Thr Glu 
            500                 505                 510         


Ala Glu Tyr Gln Thr Ser Ile Gln Glu Lys Leu Pro Leu 
        515                 520                 525 


<210>  407
<211>  526
<212>  PRT
<213>  Homo Sapiens

<400>  407

Gly Cys Arg Ala Leu Glu Glu Thr Leu Met Asp Thr Lys Trp Val Thr 
1               5                   10                  15      


Ser Glu Leu Ala Trp Thr Ser His Pro Glu Ser Gly Trp Glu Glu Val 
            20                  25                  30          


Ser Gly Tyr Asp Glu Ala Met Asn Pro Ile Arg Thr Tyr Gln Val Cys 
        35                  40                  45              


Asn Val Arg Glu Ser Ser Gln Asn Asn Trp Leu Arg Thr Gly Phe Ile 
    50                  55                  60                  


Trp Arg Arg Asp Val Gln Arg Val Tyr Val Glu Leu Lys Phe Thr Val 
65                  70                  75                  80  


Arg Asp Cys Asn Ser Ile Pro Asn Ile Pro Gly Ser Cys Lys Glu Thr 
                85                  90                  95      


Phe Asn Leu Phe Tyr Tyr Glu Ala Asp Ser Asp Val Ala Ser Ala Ser 
            100                 105                 110         


Ser Pro Phe Trp Met Glu Asn Pro Tyr Val Lys Val Asp Thr Ile Ala 
        115                 120                 125             


Pro Asp Glu Ser Phe Ser Arg Leu Asp Ala Gly Arg Val Asn Thr Lys 
    130                 135                 140                 


Val Arg Ser Phe Gly Pro Leu Ser Lys Ala Gly Phe Tyr Leu Ala Phe 
145                 150                 155                 160 


Gln Asp Gln Gly Ala Cys Met Ser Leu Ile Ser Val Arg Ala Phe Tyr 
                165                 170                 175     


Lys Lys Cys Ala Ser Thr Thr Ala Gly Phe Ala Leu Phe Pro Glu Thr 
            180                 185                 190         


Leu Thr Gly Ala Glu Pro Thr Ser Leu Val Ile Ala Pro Gly Thr Cys 
        195                 200                 205             


Ile Pro Asn Ala Val Glu Val Ser Val Pro Leu Lys Leu Tyr Cys Asn 
    210                 215                 220                 


Gly Asp Gly Glu Trp Met Val Pro Val Gly Ala Cys Thr Cys Ala Thr 
225                 230                 235                 240 


Gly His Glu Pro Ala Ala Lys Glu Ser Gln Cys Arg Pro Cys Pro Pro 
                245                 250                 255     


Gly Ser Tyr Lys Ala Lys Gln Gly Glu Gly Pro Cys Leu Pro Cys Pro 
            260                 265                 270         


Pro Asn Ser Arg Thr Thr Ser Pro Ala Ala Ser Ile Cys Thr Cys His 
        275                 280                 285             


Asn Asn Phe Tyr Arg Ala Asp Ser Asp Ser Ala Asp Ser Ala Cys Thr 
    290                 295                 300                 


Thr Val Pro Ser Pro Pro Arg Gly Val Ile Ser Asn Val Asn Glu Thr 
305                 310                 315                 320 


Ser Leu Ile Leu Glu Trp Ser Glu Pro Arg Asp Leu Gly Gly Arg Asp 
                325                 330                 335     


Asp Leu Leu Tyr Asn Val Ile Cys Lys Lys Cys His Gly Ala Gly Gly 
            340                 345                 350         


Ala Ser Ala Cys Ser Arg Cys Asp Asp Asn Val Glu Phe Val Pro Arg 
        355                 360                 365             


Gln Leu Gly Leu Thr Glu Arg Arg Val His Ile Ser His Leu Leu Ala 
    370                 375                 380                 


His Thr Arg Tyr Thr Phe Glu Val Gln Ala Val Asn Gly Val Ser Gly 
385                 390                 395                 400 


Lys Ser Pro Leu Pro Pro Arg Tyr Ala Ala Val Asn Ile Thr Thr Asn 
                405                 410                 415     


Gln Ala Ala Pro Ser Glu Val Pro Thr Leu Arg Leu His Ser Ser Ser 
            420                 425                 430         


Gly Ser Ser Leu Thr Leu Ser Trp Ala Pro Pro Glu Arg Pro Asn Gly 
        435                 440                 445             


Val Ile Leu Asp Tyr Glu Met Lys Tyr Phe Glu Lys Ser Glu Gly Ile 
    450                 455                 460                 


Ala Ser Thr Val Thr Ser Gln Met Asn Ser Val Gln Leu Asp Gly Leu 
465                 470                 475                 480 


Arg Pro Asp Ala Arg Tyr Val Val Gln Val Arg Ala Arg Thr Val Ala 
                485                 490                 495     


Gly Tyr Gly Gln Tyr Ser Arg Pro Ala Glu Phe Glu Thr Thr Ser Glu 
            500                 505                 510         


Arg Gly Ser Gly Ala Gln Gln Leu Gln Glu Gln Leu Pro Leu 
        515                 520                 525     


<210>  408
<211>  524
<212>  PRT
<213>  Homo Sapiens

<400>  408

Leu Glu Glu Thr Leu Leu Asn Thr Lys Leu Glu Thr Ala Asp Leu Lys 
1               5                   10                  15      


Trp Val Thr Phe Pro Gln Val Asp Gly Gln Trp Glu Glu Leu Ser Gly 
            20                  25                  30          


Leu Asp Glu Glu Gln His Ser Val Arg Thr Tyr Glu Val Cys Asp Val 
        35                  40                  45              


Gln Arg Ala Pro Gly Gln Ala His Trp Leu Arg Thr Gly Trp Val Pro 
    50                  55                  60                  


Arg Arg Gly Ala Val His Val Tyr Ala Thr Leu Arg Phe Thr Met Leu 
65                  70                  75                  80  


Glu Cys Leu Ser Leu Pro Arg Ala Gly Arg Ser Cys Lys Glu Thr Phe 
                85                  90                  95      


Thr Val Phe Tyr Tyr Glu Ser Asp Ala Asp Thr Ala Thr Ala Leu Thr 
            100                 105                 110         


Pro Ala Trp Met Glu Asn Pro Tyr Ile Lys Val Asp Thr Val Ala Ala 
        115                 120                 125             


Glu His Leu Thr Arg Lys Arg Pro Gly Ala Glu Ala Thr Gly Lys Val 
    130                 135                 140                 


Asn Val Arg Thr Leu Arg Leu Gly Pro Leu Ser Lys Ala Gly Phe Tyr 
145                 150                 155                 160 


Leu Ala Phe Gln Asp Gln Gly Ala Cys Met Ala Leu Leu Ser Leu His 
                165                 170                 175     


Leu Phe Tyr Lys Lys Cys Ala Gln Leu Thr Val Asn Leu Thr Arg Phe 
            180                 185                 190         


Pro Glu Thr Val Pro Arg Glu Leu Val Val Pro Val Ala Gly Ser Cys 
        195                 200                 205             


Val Val Asp Ala Val Pro Ala Pro Gly Pro Ser Pro Ser Leu Tyr Cys 
    210                 215                 220                 


Arg Glu Asp Gly Gln Trp Ala Glu Gln Pro Val Thr Gly Cys Ser Cys 
225                 230                 235                 240 


Ala Pro Gly Phe Glu Ala Ala Glu Gly Asn Thr Lys Cys Arg Ala Cys 
                245                 250                 255     


Ala Gln Gly Thr Phe Lys Pro Leu Ser Gly Glu Gly Ser Cys Gln Pro 
            260                 265                 270         


Cys Pro Ala Asn Ser His Ser Asn Thr Ile Gly Ser Ala Val Cys Gln 
        275                 280                 285             


Cys Arg Val Gly Tyr Phe Arg Ala Arg Thr Asp Pro Arg Gly Ala Pro 
    290                 295                 300                 


Cys Thr Thr Pro Pro Ser Ala Pro Arg Ser Val Val Ser Arg Leu Asn 
305                 310                 315                 320 


Gly Ser Ser Leu His Leu Glu Trp Ser Ala Pro Leu Glu Ser Gly Gly 
                325                 330                 335     


Arg Glu Asp Leu Thr Tyr Ala Leu Arg Cys Arg Glu Cys Arg Pro Gly 
            340                 345                 350         


Gly Ser Cys Ala Pro Cys Gly Gly Asp Leu Thr Phe Asp Pro Gly Pro 
        355                 360                 365             


Arg Asp Leu Val Glu Pro Trp Val Val Val Arg Gly Leu Arg Pro Asp 
    370                 375                 380                 


Phe Thr Tyr Thr Phe Glu Val Thr Ala Leu Asn Gly Val Ser Ser Leu 
385                 390                 395                 400 


Ala Thr Gly Pro Val Pro Phe Glu Pro Val Asn Val Thr Thr Asp Arg 
                405                 410                 415     


Glu Val Pro Pro Ala Val Ser Asp Ile Arg Val Thr Arg Ser Ser Pro 
            420                 425                 430         


Ser Ser Leu Ser Leu Ala Trp Ala Val Pro Arg Ala Pro Ser Gly Ala 
        435                 440                 445             


Val Leu Asp Tyr Glu Val Lys Tyr His Glu Lys Gly Ala Glu Gly Pro 
    450                 455                 460                 


Ser Ser Val Arg Phe Leu Lys Thr Ser Glu Asn Arg Ala Glu Leu Arg 
465                 470                 475                 480 


Gly Leu Lys Arg Gly Ala Ser Tyr Leu Val Gln Val Arg Ala Arg Ser 
                485                 490                 495     


Glu Ala Gly Tyr Gly Pro Phe Gly Gln Glu His His Ser Gln Thr Gln 
            500                 505                 510         


Leu Asp Glu Ser Glu Gly Trp Arg Glu Gln Leu Ala 
        515                 520                 


<210>  409
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  409

Pro Pro Ser Ala Pro Gln Glu Leu Trp Phe Glu Val Gln Gly Ser Ala 
1               5                   10                  15      


Leu Met Leu His Trp Arg Leu Pro Arg Glu Leu Gly Gly Arg Gly Asp 
            20                  25                  30          


Leu Leu Phe Asn Val Val Cys Lys Glu Cys Glu Gly Arg Gln Glu Pro 
        35                  40                  45              


Ala Ser Gly Gly Gly Gly Thr Cys His Arg Cys Arg Asp Glu Val His 
    50                  55                  60                  


Phe Asp Pro Arg Gln Arg Gly Leu Thr Glu Ser Arg Val Leu Val Gly 
65                  70                  75                  80  


Gly Leu Arg Ala His Val Pro Tyr Ile Leu Glu Val Gln Ala Val Asn 
                85                  90                  95      


Gly Val Ser Glu Leu Ser Pro Asp Pro Pro Gln Ala Ala Ala Ile Asn 
            100                 105                 110         


Val Ser Thr Ser His Glu Val Pro Ser Ala Val Pro Val Val His Gln 
        115                 120                 125             


Val Ser Arg Ala Ser Asn Ser Ile Thr Val Ser Trp Pro Gln Pro Asp 
    130                 135                 140                 


Gln Thr Asn Gly Asn Ile Leu Asp Tyr Gln Leu Arg Tyr Tyr Asp Gln 
145                 150                 155                 160 


Ala Glu Asp Glu Ser His Ser Phe Thr Leu Thr Ser Glu Thr Asn Thr 
                165                 170                 175     


Ala Thr Val Thr Gln Leu Ser Pro Gly His Ile Tyr Gly Phe Gln Val 
            180                 185                 190         


Arg Ala Arg Thr Ala Ala Gly His Gly Pro Tyr Gly Gly Lys Val Tyr 
        195                 200                 205             


Phe Gln Thr Leu Pro Gln Gly Glu Leu Ser Ser Gln Leu Pro Glu Arg 
    210                 215                 220                 


Leu Ser 
225     


<210>  410
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  410

Ala Pro Pro Arg Leu Ile Cys Asp Ser Arg Val Leu Glu Arg Tyr Leu 
1               5                   10                  15      


Leu Glu Ala Lys Glu Ala Glu Asn Ile Thr Thr Gly Cys Ala Glu His 
            20                  25                  30          


Cys Ser Leu Asn Glu Asn Ile Thr Val Pro Asp Thr Lys Val Asn Phe 
        35                  40                  45              


Tyr Ala Trp Lys Arg Met Glu Val Gly Gln Gln Ala Val Glu Val Trp 
    50                  55                  60                  


Gln Gly Leu Ala Leu Leu Ser Glu Ala Val Leu Arg Gly Gln Ala Leu 
65                  70                  75                  80  


Leu Val Asn Ser Ser Gln Pro Trp Glu Pro Leu Gln Leu His Val Asp 
                85                  90                  95      


Lys Ala Val Ser Gly Leu Arg Ser Leu Thr Thr Leu Leu Arg Ala Leu 
            100                 105                 110         


Gly Ala Gln Lys Glu Ala Ile Ser Pro Pro Asp Ala Ala Ser Ala Ala 
        115                 120                 125             


Pro Leu Arg Thr Ile Thr Ala Asp Thr Phe Arg Lys Leu Phe Arg Val 
    130                 135                 140                 


Tyr Ser Asn Phe Leu Arg Gly Lys Leu Lys Leu Tyr Thr Gly Glu Ala 
145                 150                 155                 160 


Cys Arg Thr Gly Asp Arg 
                165     


<210>  411
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  411

Ala Pro Pro Pro Asn Leu Pro Asp Pro Lys Phe Glu Ser Lys Ala Ala 
1               5                   10                  15      


Leu Leu Ala Ala Arg Gly Pro Glu Glu Leu Leu Cys Phe Thr Glu Arg 
            20                  25                  30          


Leu Glu Asp Leu Val Cys Phe Trp Glu Glu Ala Ala Ser Ala Gly Val 
        35                  40                  45              


Gly Pro Gly Asn Tyr Ser Phe Ser Tyr Gln Leu Glu Asp Glu Pro Trp 
    50                  55                  60                  


Lys Leu Cys Arg Leu His Gln Ala Pro Thr Ala Arg Gly Ala Val Arg 
65                  70                  75                  80  


Phe Trp Cys Ser Leu Pro Thr Ala Asp Thr Ser Ser Phe Val Pro Leu 
                85                  90                  95      


Glu Leu Arg Val Thr Ala Ala Ser Gly Ala Pro Arg Tyr His Arg Val 
            100                 105                 110         


Ile His Ile Asn Glu Val Val Leu Leu Asp Ala Pro Val Gly Leu Val 
        115                 120                 125             


Ala Arg Leu Ala Asp Glu Ser Gly His Val Val Leu Arg Trp Leu Pro 
    130                 135                 140                 


Pro Pro Glu Thr Pro Met Thr Ser His Ile Arg Tyr Glu Val Asp Val 
145                 150                 155                 160 


Ser Ala Gly Asn Gly Ala Gly Ser Val Gln Arg Val Glu Ile Leu Glu 
                165                 170                 175     


Gly Arg Thr Glu Cys Val Leu Ser Asn Leu Arg Gly Arg Thr Arg Tyr 
            180                 185                 190         


Thr Phe Ala Val Arg Ala Arg Met Ala Glu Pro Ser Phe Gly Gly Phe 
        195                 200                 205             


Trp Ser Ala Trp Ser Glu Pro Val Ser Leu Leu Thr Pro Ser Asp Leu 
    210                 215                 220                 


Asp Pro 
225     


<210>  412
<211>  303
<212>  PRT
<213>  Homo Sapiens

<400>  412

Ala Pro Thr Leu Glu Ser Ile Asn Tyr Asp Ser Glu Thr Tyr Asp Ala 
1               5                   10                  15      


Thr Leu Glu Asp Leu Asp Asn Leu Tyr Asn Tyr Glu Asn Ile Pro Val 
            20                  25                  30          


Gly Lys Val Glu Ile Glu Ile Ala Thr Val Met Pro Ser Gly Asn Arg 
        35                  40                  45              


Glu Leu Leu Thr Pro Pro Pro Gln Pro Glu Lys Ala Gln Glu Glu Glu 
    50                  55                  60                  


Glu Glu Glu Glu Ser Thr Pro Arg Leu Ile Asp Gly Ser Ser Pro Gln 
65                  70                  75                  80  


Glu Pro Glu Phe Thr Gly Val Leu Gly Pro His Thr Asn Glu Asp Phe 
                85                  90                  95      


Pro Thr Cys Leu Leu Cys Thr Cys Ile Ser Thr Thr Val Tyr Cys Asp 
            100                 105                 110         


Asp His Glu Leu Asp Ala Ile Pro Pro Leu Pro Lys Asn Thr Ala Tyr 
        115                 120                 125             


Phe Tyr Ser Arg Phe Asn Arg Ile Lys Lys Ile Asn Lys Asn Asp Phe 
    130                 135                 140                 


Ala Ser Leu Ser Asp Leu Lys Arg Ile Asp Leu Thr Ser Asn Leu Ile 
145                 150                 155                 160 


Ser Glu Ile Asp Glu Asp Ala Phe Arg Lys Leu Pro Gln Leu Arg Glu 
                165                 170                 175     


Leu Val Leu Arg Asp Asn Lys Ile Arg Gln Leu Pro Glu Leu Pro Thr 
            180                 185                 190         


Thr Leu Thr Phe Ile Asp Ile Ser Asn Asn Arg Leu Gly Arg Lys Gly 
        195                 200                 205             


Ile Lys Gln Glu Ala Phe Lys Asp Met Tyr Asp Leu His His Leu Tyr 
    210                 215                 220                 


Leu Thr Asp Asn Asn Leu Asp His Ile Pro Leu Pro Leu Pro Glu Asn 
225                 230                 235                 240 


Leu Arg Ala Leu His Leu Gln Asn Asn Asn Ile Leu Glu Met His Glu 
                245                 250                 255     


Asp Thr Phe Cys Asn Val Lys Asn Leu Thr Tyr Ile Arg Lys Ala Leu 
            260                 265                 270         


Glu Asp Ile Arg Leu Asp Gly Asn Pro Ile Asn Leu Ser Lys Thr Pro 
        275                 280                 285             


Gln Ala Tyr Met Cys Leu Pro Arg Leu Pro Val Gly Ser Leu Val 
    290                 295                 300             


<210>  413
<211>  630
<212>  PRT
<213>  Homo Sapiens

<400>  413

Thr Gln Val Cys Thr Gly Thr Asp Met Lys Leu Arg Leu Pro Ala Ser 
1               5                   10                  15      


Pro Glu Thr His Leu Asp Met Leu Arg His Leu Tyr Gln Gly Cys Gln 
            20                  25                  30          


Val Val Gln Gly Asn Leu Glu Leu Thr Tyr Leu Pro Thr Asn Ala Ser 
        35                  40                  45              


Leu Ser Phe Leu Gln Asp Ile Gln Glu Val Gln Gly Tyr Val Leu Ile 
    50                  55                  60                  


Ala His Asn Gln Val Arg Gln Val Pro Leu Gln Arg Leu Arg Ile Val 
65                  70                  75                  80  


Arg Gly Thr Gln Leu Phe Glu Asp Asn Tyr Ala Leu Ala Val Leu Asp 
                85                  90                  95      


Asn Gly Asp Pro Leu Asn Asn Thr Thr Pro Val Thr Gly Ala Ser Pro 
            100                 105                 110         


Gly Gly Leu Arg Glu Leu Gln Leu Arg Ser Leu Thr Glu Ile Leu Lys 
        115                 120                 125             


Gly Gly Val Leu Ile Gln Arg Asn Pro Gln Leu Cys Tyr Gln Asp Thr 
    130                 135                 140                 


Ile Leu Trp Lys Asp Ile Phe His Lys Asn Asn Gln Leu Ala Leu Thr 
145                 150                 155                 160 


Leu Ile Asp Thr Asn Arg Ser Arg Ala Cys His Pro Cys Ser Pro Met 
                165                 170                 175     


Cys Lys Gly Ser Arg Cys Trp Gly Glu Ser Ser Glu Asp Cys Gln Ser 
            180                 185                 190         


Leu Thr Arg Thr Val Cys Ala Gly Gly Cys Ala Arg Cys Lys Gly Pro 
        195                 200                 205             


Leu Pro Thr Asp Cys Cys His Glu Gln Cys Ala Ala Gly Cys Thr Gly 
    210                 215                 220                 


Pro Lys His Ser Asp Cys Leu Ala Cys Leu His Phe Asn His Ser Gly 
225                 230                 235                 240 


Ile Cys Glu Leu His Cys Pro Ala Leu Val Thr Tyr Asn Thr Asp Thr 
                245                 250                 255     


Phe Glu Ser Met Pro Asn Pro Glu Gly Arg Tyr Thr Phe Gly Ala Ser 
            260                 265                 270         


Cys Val Thr Ala Cys Pro Tyr Asn Tyr Leu Ser Thr Asp Val Gly Ser 
        275                 280                 285             


Cys Thr Leu Val Cys Pro Leu His Asn Gln Glu Val Thr Ala Glu Asp 
    290                 295                 300                 


Gly Thr Gln Arg Cys Glu Lys Cys Ser Lys Pro Cys Ala Arg Val Cys 
305                 310                 315                 320 


Tyr Gly Leu Gly Met Glu His Leu Arg Glu Val Arg Ala Val Thr Ser 
                325                 330                 335     


Ala Asn Ile Gln Glu Phe Ala Gly Cys Lys Lys Ile Phe Gly Ser Leu 
            340                 345                 350         


Ala Phe Leu Pro Glu Ser Phe Asp Gly Asp Pro Ala Ser Asn Thr Ala 
        355                 360                 365             


Pro Leu Gln Pro Glu Gln Leu Gln Val Phe Glu Thr Leu Glu Glu Ile 
    370                 375                 380                 


Thr Gly Tyr Leu Tyr Ile Ser Ala Trp Pro Asp Ser Leu Pro Asp Leu 
385                 390                 395                 400 


Ser Val Phe Gln Asn Leu Gln Val Ile Arg Gly Arg Ile Leu His Asn 
                405                 410                 415     


Gly Ala Tyr Ser Leu Thr Leu Gln Gly Leu Gly Ile Ser Trp Leu Gly 
            420                 425                 430         


Leu Arg Ser Leu Arg Glu Leu Gly Ser Gly Leu Ala Leu Ile His His 
        435                 440                 445             


Asn Thr His Leu Cys Phe Val His Thr Val Pro Trp Asp Gln Leu Phe 
    450                 455                 460                 


Arg Asn Pro His Gln Ala Leu Leu His Thr Ala Asn Arg Pro Glu Asp 
465                 470                 475                 480 


Glu Cys Val Gly Glu Gly Leu Ala Cys His Gln Leu Cys Ala Arg Gly 
                485                 490                 495     


His Cys Trp Gly Pro Gly Pro Thr Gln Cys Val Asn Cys Ser Gln Phe 
            500                 505                 510         


Leu Arg Gly Gln Glu Cys Val Glu Glu Cys Arg Val Leu Gln Gly Leu 
        515                 520                 525             


Pro Arg Glu Tyr Val Asn Ala Arg His Cys Leu Pro Cys His Pro Glu 
    530                 535                 540                 


Cys Gln Pro Gln Asn Gly Ser Val Thr Cys Phe Gly Pro Glu Ala Asp 
545                 550                 555                 560 


Gln Cys Val Ala Cys Ala His Tyr Lys Asp Pro Pro Phe Cys Val Ala 
                565                 570                 575     


Arg Cys Pro Ser Gly Val Lys Pro Asp Leu Ser Tyr Met Pro Ile Trp 
            580                 585                 590         


Lys Phe Pro Asp Glu Glu Gly Ala Cys Gln Pro Cys Pro Ile Asn Cys 
        595                 600                 605             


Thr His Ser Cys Val Asp Leu Asp Asp Lys Gly Cys Pro Ala Glu Gln 
    610                 615                 620                 


Arg Ala Ser Pro Leu Thr 
625                 630 


<210>  414
<211>  624
<212>  PRT
<213>  Homo Sapiens

<400>  414

Ser Glu Val Gly Asn Ser Gln Ala Val Cys Pro Gly Thr Leu Asn Gly 
1               5                   10                  15      


Leu Ser Val Thr Gly Asp Ala Glu Asn Gln Tyr Gln Thr Leu Tyr Lys 
            20                  25                  30          


Leu Tyr Glu Arg Cys Glu Val Val Met Gly Asn Leu Glu Ile Val Leu 
        35                  40                  45              


Thr Gly His Asn Ala Asp Leu Ser Phe Leu Gln Trp Ile Arg Glu Val 
    50                  55                  60                  


Thr Gly Tyr Val Leu Val Ala Met Asn Glu Phe Ser Thr Leu Pro Leu 
65                  70                  75                  80  


Pro Asn Leu Arg Val Val Arg Gly Thr Gln Val Tyr Asp Gly Lys Phe 
                85                  90                  95      


Ala Ile Phe Val Met Leu Asn Tyr Asn Thr Asn Ser Ser His Ala Leu 
            100                 105                 110         


Arg Gln Leu Arg Leu Thr Gln Leu Thr Glu Ile Leu Ser Gly Gly Val 
        115                 120                 125             


Tyr Ile Glu Lys Asn Asp Lys Leu Cys His Met Asp Thr Ile Asp Trp 
    130                 135                 140                 


Arg Asp Ile Val Arg Asp Arg Asp Ala Glu Ile Val Val Lys Asp Asn 
145                 150                 155                 160 


Gly Arg Ser Cys Pro Pro Cys His Glu Val Cys Lys Gly Arg Cys Trp 
                165                 170                 175     


Gly Pro Gly Ser Glu Asp Cys Gln Thr Leu Thr Lys Thr Ile Cys Ala 
            180                 185                 190         


Pro Gln Cys Asn Gly His Cys Phe Gly Pro Asn Pro Asn Gln Cys Cys 
        195                 200                 205             


His Asp Glu Cys Ala Gly Gly Cys Ser Gly Pro Gln Asp Thr Asp Cys 
    210                 215                 220                 


Phe Ala Cys Arg His Phe Asn Asp Ser Gly Ala Cys Val Pro Arg Cys 
225                 230                 235                 240 


Pro Gln Pro Leu Val Tyr Asn Lys Leu Thr Phe Gln Leu Glu Pro Asn 
                245                 250                 255     


Pro His Thr Lys Tyr Gln Tyr Gly Gly Val Cys Val Ala Ser Cys Pro 
            260                 265                 270         


His Asn Phe Val Val Asp Gln Thr Ser Cys Val Arg Ala Cys Pro Pro 
        275                 280                 285             


Asp Lys Met Glu Val Asp Lys Asn Gly Leu Lys Met Cys Glu Pro Cys 
    290                 295                 300                 


Gly Gly Leu Cys Pro Lys Ala Cys Glu Gly Thr Gly Ser Gly Ser Arg 
305                 310                 315                 320 


Phe Gln Thr Val Asp Ser Ser Asn Ile Asp Gly Phe Val Asn Cys Thr 
                325                 330                 335     


Lys Ile Leu Gly Asn Leu Asp Phe Leu Ile Thr Gly Leu Asn Gly Asp 
            340                 345                 350         


Pro Trp His Lys Ile Pro Ala Leu Asp Pro Glu Lys Leu Asn Val Phe 
        355                 360                 365             


Arg Thr Val Arg Glu Ile Thr Gly Tyr Leu Asn Ile Gln Ser Trp Pro 
    370                 375                 380                 


Pro His Met His Asn Phe Ser Val Phe Ser Asn Leu Thr Thr Ile Gly 
385                 390                 395                 400 


Gly Arg Ser Leu Tyr Asn Arg Gly Phe Ser Leu Leu Ile Met Lys Asn 
                405                 410                 415     


Leu Asn Val Thr Ser Leu Gly Phe Arg Ser Leu Lys Glu Ile Ser Ala 
            420                 425                 430         


Gly Arg Ile Tyr Ile Ser Ala Asn Arg Gln Leu Cys Tyr His His Ser 
        435                 440                 445             


Leu Asn Trp Thr Lys Val Leu Arg Gly Pro Thr Glu Glu Arg Leu Asp 
    450                 455                 460                 


Ile Lys His Asn Arg Pro Arg Arg Asp Cys Val Ala Glu Gly Lys Val 
465                 470                 475                 480 


Cys Asp Pro Leu Cys Ser Ser Gly Gly Cys Trp Gly Pro Gly Pro Gly 
                485                 490                 495     


Gln Cys Leu Ser Cys Arg Asn Tyr Ser Arg Gly Gly Val Cys Val Thr 
            500                 505                 510         


His Cys Asn Phe Leu Asn Gly Glu Pro Arg Glu Phe Ala His Glu Ala 
        515                 520                 525             


Glu Cys Phe Ser Cys His Pro Glu Cys Gln Pro Met Glu Gly Thr Ala 
    530                 535                 540                 


Thr Cys Asn Gly Ser Gly Ser Asp Thr Cys Ala Gln Cys Ala His Phe 
545                 550                 555                 560 


Arg Asp Gly Pro His Cys Val Ser Ser Cys Pro His Gly Val Leu Gly 
                565                 570                 575     


Ala Lys Gly Pro Ile Tyr Lys Tyr Pro Asp Val Gln Asn Glu Cys Arg 
            580                 585                 590         


Pro Cys His Glu Asn Cys Thr Gln Gly Cys Lys Gly Pro Glu Leu Gln 
        595                 600                 605             


Asp Cys Leu Gly Gln Thr Leu Val Leu Ile Gly Lys Thr His Leu Thr 
    610                 615                 620                 


<210>  415
<211>  626
<212>  PRT
<213>  Homo Sapiens

<400>  415

Gln Ser Val Cys Ala Gly Thr Glu Asn Lys Leu Ser Ser Leu Ser Asp 
1               5                   10                  15      


Leu Glu Gln Gln Tyr Arg Ala Leu Arg Lys Tyr Tyr Glu Asn Cys Glu 
            20                  25                  30          


Val Val Met Gly Asn Leu Glu Ile Thr Ser Ile Glu His Asn Arg Asp 
        35                  40                  45              


Leu Ser Phe Leu Arg Ser Val Arg Glu Val Thr Gly Tyr Val Leu Val 
    50                  55                  60                  


Ala Leu Asn Gln Phe Arg Tyr Leu Pro Leu Glu Asn Leu Arg Ile Ile 
65                  70                  75                  80  


Arg Gly Thr Lys Leu Tyr Glu Asp Arg Tyr Ala Leu Ala Ile Phe Leu 
                85                  90                  95      


Asn Tyr Arg Lys Asp Gly Asn Phe Gly Leu Gln Glu Leu Gly Leu Lys 
            100                 105                 110         


Asn Leu Thr Glu Ile Leu Asn Gly Gly Val Tyr Val Asp Gln Asn Lys 
        115                 120                 125             


Phe Leu Cys Tyr Ala Asp Thr Ile His Trp Gln Asp Ile Val Arg Asn 
    130                 135                 140                 


Pro Trp Pro Ser Asn Leu Thr Leu Val Ser Thr Asn Gly Ser Ser Gly 
145                 150                 155                 160 


Cys Gly Arg Cys His Lys Ser Cys Thr Gly Arg Cys Trp Gly Pro Thr 
                165                 170                 175     


Glu Asn His Cys Gln Thr Leu Thr Arg Thr Val Cys Ala Glu Gln Cys 
            180                 185                 190         


Asp Gly Arg Cys Tyr Gly Pro Tyr Val Ser Asp Cys Cys His Arg Glu 
        195                 200                 205             


Cys Ala Gly Gly Cys Ser Gly Pro Lys Asp Thr Asp Cys Phe Ala Cys 
    210                 215                 220                 


Met Asn Phe Asn Asp Ser Gly Ala Cys Val Thr Gln Cys Pro Gln Thr 
225                 230                 235                 240 


Phe Val Tyr Asn Pro Thr Thr Phe Gln Leu Glu His Asn Phe Asn Ala 
                245                 250                 255     


Lys Tyr Thr Tyr Gly Ala Phe Cys Val Lys Lys Cys Pro His Asn Phe 
            260                 265                 270         


Val Val Asp Ser Ser Ser Cys Val Arg Ala Cys Pro Ser Ser Lys Met 
        275                 280                 285             


Glu Val Glu Glu Asn Gly Ile Lys Met Cys Lys Pro Cys Thr Asp Ile 
    290                 295                 300                 


Cys Pro Lys Ala Cys Asp Gly Ile Gly Thr Gly Ser Leu Met Ser Ala 
305                 310                 315                 320 


Gln Thr Val Asp Ser Ser Asn Ile Asp Lys Phe Ile Asn Cys Thr Lys 
                325                 330                 335     


Ile Asn Gly Asn Leu Ile Phe Leu Val Thr Gly Ile His Gly Asp Pro 
            340                 345                 350         


Tyr Asn Ala Ile Glu Ala Ile Asp Pro Glu Lys Leu Asn Val Phe Arg 
        355                 360                 365             


Thr Val Arg Glu Ile Thr Gly Phe Leu Asn Ile Gln Ser Trp Pro Pro 
    370                 375                 380                 


Asn Met Thr Asp Phe Ser Val Phe Ser Asn Leu Val Thr Ile Gly Gly 
385                 390                 395                 400 


Arg Val Leu Tyr Ser Gly Leu Ser Leu Leu Ile Leu Lys Gln Gln Gly 
                405                 410                 415     


Ile Thr Ser Leu Gln Phe Gln Ser Leu Lys Glu Ile Ser Ala Gly Asn 
            420                 425                 430         


Ile Tyr Ile Thr Asp Asn Ser Asn Leu Cys Tyr Tyr His Thr Ile Asn 
        435                 440                 445             


Trp Thr Thr Leu Phe Ser Thr Ile Asn Gln Arg Ile Val Ile Arg Asp 
    450                 455                 460                 


Asn Arg Lys Ala Glu Asn Cys Thr Ala Glu Gly Met Val Cys Asn His 
465                 470                 475                 480 


Leu Cys Ser Ser Asp Gly Cys Trp Gly Pro Gly Pro Asp Gln Cys Leu 
                485                 490                 495     


Ser Cys Arg Arg Phe Ser Arg Gly Arg Ile Cys Ile Glu Ser Cys Asn 
            500                 505                 510         


Leu Tyr Asp Gly Glu Phe Arg Glu Phe Glu Asn Gly Ser Ile Cys Val 
        515                 520                 525             


Glu Cys Asp Pro Gln Cys Glu Lys Met Glu Asp Gly Leu Leu Thr Cys 
    530                 535                 540                 


His Gly Pro Gly Pro Asp Asn Cys Thr Lys Cys Ser His Phe Lys Asp 
545                 550                 555                 560 


Gly Pro Asn Cys Val Glu Lys Cys Pro Asp Gly Leu Gln Gly Ala Asn 
                565                 570                 575     


Ser Phe Ile Phe Lys Tyr Ala Asp Pro Asp Arg Glu Cys His Pro Cys 
            580                 585                 590         


His Pro Asn Cys Thr Gln Gly Cys Asn Gly Pro Thr Ser His Asp Cys 
        595                 600                 605             


Ile Tyr Tyr Pro Trp Thr Gly His Ser Thr Leu Pro Gln His Ala Arg 
    610                 615                 620                 


Thr Pro 
625     


<210>  416
<211>  46
<212>  PRT
<213>  Homo Sapiens

<400>  416

Val Ser Ile Thr Lys Cys Ser Ser Asp Met Asn Gly Tyr Cys Leu His 
1               5                   10                  15      


Gly Gln Cys Ile Tyr Leu Val Asp Met Ser Gln Asn Tyr Cys Arg Cys 
            20                  25                  30          


Glu Val Gly Tyr Thr Gly Val Arg Cys Glu His Phe Phe Leu 
        35                  40                  45      


<210>  417
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  417

His Ala Gly Asp Ala Gly Lys Phe His Val Ala Leu Leu Gly Gly Thr 
1               5                   10                  15      


Ala Glu Leu Leu Cys Pro Leu Ser Leu Trp Pro Gly Thr Val Pro Lys 
            20                  25                  30          


Glu Val Arg Trp Leu Arg Ser Pro Phe Pro Gln Arg Ser Gln Ala Val 
        35                  40                  45              


His Ile Phe Arg Asp Gly Lys Asp Gln Asp Glu Asp Leu Met Pro Glu 
    50                  55                  60                  


Tyr Lys Gly Arg Thr Val Leu Val Arg Asp Ala Gln Glu Gly Ser Val 
65                  70                  75                  80  


Thr Leu Gln Ile Leu Asp Val Arg Leu Glu Asp Gln Gly Ser Tyr Arg 
                85                  90                  95      


Cys Leu Ile Gln Val Gly Asn Leu Ser Lys Glu Asp Thr Val Ile Leu 
            100                 105                 110         


Gln Val Ala Ala Pro Ser Val Gly Ser Leu Ser Pro Ser Ala 
        115                 120                 125     


<210>  418
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  418

Gln Leu Gln Leu His Leu Pro Ala Asn Arg Leu Gln Ala Val Glu Gly 
1               5                   10                  15      


Gly Glu Val Val Leu Pro Ala Trp Tyr Thr Leu His Gly Glu Val Ser 
            20                  25                  30          


Ser Ser Gln Pro Trp Glu Val Pro Phe Val Met Trp Phe Phe Lys Gln 
        35                  40                  45              


Lys Glu Lys Glu Asp Gln Val Leu Ser Tyr Ile Asn Gly Val Thr Thr 
    50                  55                  60                  


Ser Lys Pro Gly Val Ser Leu Val Tyr Ser Met Pro Ser Arg Asn Leu 
65                  70                  75                  80  


Ser Leu Arg Leu Glu Gly Leu Gln Glu Lys Asp Ser Gly Pro Tyr Ser 
                85                  90                  95      


Cys Ser Val Asn Val Gln Asp Lys Gln Gly Lys Ser Arg Gly His Ser 
            100                 105                 110         


Ile Lys Thr Leu Glu Leu Asn Val Leu Val Pro Pro Ala Pro Pro Ser 
        115                 120                 125             


Cys Arg Leu Gln Gly Val Pro His Val Gly Ala Asn Val Thr Leu Ser 
    130                 135                 140                 


Cys Gln Ser Pro Arg Ser Lys Pro Ala Val Gln Tyr Gln Trp Asp Arg 
145                 150                 155                 160 


Gln Leu Pro Ser Phe Gln Thr Phe Phe Ala Pro Ala Leu Asp Val Ile 
                165                 170                 175     


Arg Gly Ser Leu Ser Leu Thr Asn Leu Ser Ser Ser Met Ala Gly Val 
            180                 185                 190         


Tyr Val Cys Lys Ala His Asn Glu Val Gly Thr Ala Gln Cys Asn Val 
        195                 200                 205             


Thr Leu Glu Val Ser Thr Gly Pro Gly Ala Ala 
    210                 215                 


<210>  419
<211>  573
<212>  PRT
<213>  Homo Sapiens

<400>  419

Lys Thr Cys Arg Arg Gln Leu Val Glu Glu Trp His Pro Gln Pro Ser 
1               5                   10                  15      


Ser Tyr Val Val Asn Trp Thr Leu Thr Glu Asn Ile Cys Leu Asp Phe 
            20                  25                  30          


Tyr Arg Asp Cys Trp Phe Leu Gly Val Asn Thr Lys Ile Asp Thr Ser 
        35                  40                  45              


Gly Asn Gln Ala Val Pro Gln Ile Cys Pro Leu Gln Ile Gln Leu Gly 
    50                  55                  60                  


Asp Ile Leu Val Ile Ser Ser Glu Pro Ser Leu Gln Phe Pro Glu Ile 
65                  70                  75                  80  


Asn Leu Met Asn Val Ser Glu Thr Ser Phe Val Gly Cys Val Gln Asn 
                85                  90                  95      


Thr Thr Met Glu Asp Gln Leu Leu Phe Gly Cys Arg Leu Lys Gly Met 
            100                 105                 110         


His Thr Val Asn Ser Lys Trp Leu Ser Val Gly Thr His Tyr Phe Ile 
        115                 120                 125             


Thr Val Met Ala Ser Gly Pro Ser Pro Cys Pro Leu Gly Leu Arg Leu 
    130                 135                 140                 


Asn Val Thr Val Lys Gln Gln Phe Cys Gln Glu Ser Leu Ser Ser Glu 
145                 150                 155                 160 


Phe Cys Ser Gly His Gly Lys Cys Leu Ser Glu Ala Trp Ser Lys Thr 
                165                 170                 175     


Tyr Ser Cys His Cys Gln Pro Pro Phe Ser Gly Lys Tyr Cys Gln Glu 
            180                 185                 190         


Leu Asp Ala Cys Ser Phe Lys Pro Cys Lys Asn Asn Gly Ser Cys Ile 
        195                 200                 205             


Asn Lys Arg Glu Asn Trp Asp Glu Gln Ala Tyr Glu Cys Val Cys His 
    210                 215                 220                 


Pro Pro Phe Thr Gly Lys Asn Cys Ser Glu Ile Ile Gly Gln Cys Gln 
225                 230                 235                 240 


Pro His Val Cys Phe His Gly Asn Cys Ser Asn Ile Thr Ser Asn Ser 
                245                 250                 255     


Phe Ile Cys Glu Cys Asp Glu Gln Phe Ser Gly Pro Phe Cys Glu Val 
            260                 265                 270         


Ser Ala Lys Pro Cys Val Ser Leu Leu Phe Trp Lys Arg Gly Ile Cys 
        275                 280                 285             


Pro Asn Ser Ser Ser Ala Tyr Thr Tyr Glu Cys Pro Lys Gly Ser Ser 
    290                 295                 300                 


Ser Gln Asn Gly Glu Thr Asp Val Ser Glu Phe Ser Leu Val Pro Cys 
305                 310                 315                 320 


Gln Asn Gly Thr Asp Cys Ile Lys Ile Ser Asn Asp Val Met Cys Ile 
                325                 330                 335     


Cys Ser Pro Ile Phe Thr Asp Leu Leu Cys Lys Ser Ile Gln Thr Ser 
            340                 345                 350         


Cys Glu Ser Phe Pro Leu Arg Asn Asn Ala Thr Cys Lys Lys Cys Glu 
        355                 360                 365             


Lys Asp Tyr Pro Cys Ser Cys Ile Ser Gly Phe Thr Glu Lys Asn Cys 
    370                 375                 380                 


Glu Lys Ala Ile Asp His Cys Lys Leu Leu Ser Ile Asn Cys Leu Asn 
385                 390                 395                 400 


Glu Glu Trp Cys Phe Asn Ile Ile Gly Arg Phe Lys Tyr Val Cys Ile 
                405                 410                 415     


Pro Gly Cys Thr Lys Asn Pro Cys Trp Phe Leu Lys Asn Val Tyr Leu 
            420                 425                 430         


Ile His Gln His Leu Cys Tyr Cys Gly Val Thr Phe His Gly Ile Cys 
        435                 440                 445             


Gln Asp Lys Gly Pro Ala Gln Phe Glu Tyr Val Trp Gln Leu Gly Phe 
    450                 455                 460                 


Ala Gly Ser Glu Gly Glu Lys Cys Gln Gly Val Ile Asp Ala Tyr Phe 
465                 470                 475                 480 


Phe Leu Ala Ala Asn Cys Thr Glu Asp Ala Thr Tyr Val Asn Asp Pro 
                485                 490                 495     


Glu Asp Asn Asn Ser Ser Cys Trp Phe Pro His Glu Gly Thr Lys Glu 
            500                 505                 510         


Ile Cys Ala Asn Gly Cys Ser Cys Leu Ser Glu Glu Asp Ser Gln Glu 
        515                 520                 525             


Tyr Arg Tyr Leu Cys Phe Leu Arg Trp Ala Gly Asn Met Tyr Leu Glu 
    530                 535                 540                 


Asn Thr Thr Asp Asp Gln Glu Asn Glu Cys Gln His Glu Ala Val Cys 
545                 550                 555                 560 


Lys Asp Glu Ile Asn Arg Pro Arg Tyr Leu Cys Ile Ile 
                565                 570             


<210>  420
<211>  1464
<212>  PRT
<213>  Homo Sapiens

<400>  420

Ala Thr Gly Gly Gly Gly Cys Gly Cys Cys Cys Ala Cys Thr Gly Cys 
1               5                   10                  15      


Ala Cys Cys Thr Cys Gly Thr Cys Cys Thr Gly Cys Thr Cys Ala Gly 
            20                  25                  30          


Thr Gly Cys Cys Thr Cys Cys Cys Thr Gly Gly Cys Thr Gly Gly Cys 
        35                  40                  45              


Cys Thr Cys Cys Thr Gly Cys Thr Gly Cys Thr Cys Gly Gly Gly Gly 
    50                  55                  60                  


Ala Ala Ala Gly Thr Cys Thr Gly Thr Thr Cys Ala Thr Cys Cys Gly 
65                  70                  75                  80  


Cys Ala Gly Gly Gly Ala Gly Cys Ala Gly Gly Cys Cys Ala Ala Cys 
                85                  90                  95      


Ala Ala Cys Ala Thr Cys Cys Thr Gly Gly Cys Gly Ala Gly Gly Gly 
            100                 105                 110         


Thr Cys Ala Cys Gly Ala Gly Gly Gly Cys Cys Ala Ala Thr Thr Cys 
        115                 120                 125             


Cys Thr Thr Thr Cys Thr Thr Gly Ala Ala Gly Ala Gly Ala Thr Gly 
    130                 135                 140                 


Ala Ala Gly Ala Ala Ala Gly Gly Ala Cys Ala Cys Cys Thr Cys Gly 
145                 150                 155                 160 


Ala Ala Ala Gly Ala Gly Ala Gly Thr Gly Cys Ala Thr Gly Gly Ala 
                165                 170                 175     


Ala Gly Ala Gly Ala Cys Cys Thr Gly Cys Thr Cys Ala Thr Ala Cys 
            180                 185                 190         


Gly Ala Ala Gly Ala Gly Gly Cys Cys Cys Gly Cys Gly Ala Gly Gly 
        195                 200                 205             


Thr Cys Thr Thr Thr Gly Ala Gly Gly Ala Cys Ala Gly Cys Gly Ala 
    210                 215                 220                 


Cys Ala Ala Gly Ala Cys Gly Ala Ala Thr Gly Ala Ala Thr Thr Cys 
225                 230                 235                 240 


Thr Gly Gly Ala Ala Thr Ala Ala Ala Thr Ala Cys Ala Ala Ala Gly 
                245                 250                 255     


Ala Thr Gly Gly Cys Gly Ala Cys Cys Ala Gly Thr Gly Thr Gly Ala 
            260                 265                 270         


Gly Ala Cys Cys Ala Gly Thr Cys Cys Thr Thr Gly Cys Cys Ala Gly 
        275                 280                 285             


Ala Ala Cys Cys Ala Gly Gly Gly Cys Ala Ala Ala Thr Gly Thr Ala 
    290                 295                 300                 


Ala Ala Gly Ala Cys Gly Gly Cys Cys Thr Cys Gly Gly Gly Gly Ala 
305                 310                 315                 320 


Ala Thr Ala Cys Ala Cys Cys Thr Gly Cys Ala Cys Cys Thr Gly Thr 
                325                 330                 335     


Thr Thr Ala Gly Ala Ala Gly Gly Ala Thr Thr Cys Gly Ala Ala Gly 
            340                 345                 350         


Gly Cys Ala Ala Ala Ala Ala Cys Thr Gly Thr Gly Ala Ala Thr Thr 
        355                 360                 365             


Ala Thr Thr Cys Ala Cys Ala Cys Gly Gly Ala Ala Gly Cys Thr Cys 
    370                 375                 380                 


Thr Gly Cys Ala Gly Cys Cys Thr Gly Gly Ala Cys Ala Ala Cys Gly 
385                 390                 395                 400 


Gly Gly Gly Ala Cys Thr Gly Thr Gly Ala Cys Cys Ala Gly Thr Thr 
                405                 410                 415     


Cys Thr Gly Cys Cys Ala Cys Gly Ala Gly Gly Ala Ala Cys Ala Gly 
            420                 425                 430         


Ala Ala Cys Thr Cys Thr Gly Thr Gly Gly Thr Gly Thr Gly Cys Thr 
        435                 440                 445             


Cys Cys Thr Gly Cys Gly Cys Cys Cys Gly Cys Gly Gly Gly Thr Ala 
    450                 455                 460                 


Cys Ala Cys Cys Cys Thr Gly Gly Cys Thr Gly Ala Cys Ala Ala Cys 
465                 470                 475                 480 


Gly Gly Cys Ala Ala Gly Gly Cys Cys Thr Gly Cys Ala Thr Thr Cys 
                485                 490                 495     


Cys Cys Ala Cys Ala Gly Gly Gly Cys Cys Cys Thr Ala Cys Cys Cys 
            500                 505                 510         


Cys Thr Gly Thr Gly Gly Gly Ala Ala Ala Cys Ala Gly Ala Cys Cys 
        515                 520                 525             


Cys Thr Gly Gly Ala Ala Cys Gly Cys Ala Gly Gly Ala Ala Gly Ala 
    530                 535                 540                 


Gly Gly Thr Cys Ala Gly Thr Gly Gly Cys Cys Cys Ala Gly Gly Cys 
545                 550                 555                 560 


Cys Ala Cys Cys Ala Gly Cys Ala Gly Cys Ala Gly Cys Gly Gly Gly 
                565                 570                 575     


Gly Ala Gly Gly Cys Cys Cys Cys Thr Gly Ala Cys Ala Gly Cys Ala 
            580                 585                 590         


Thr Cys Ala Cys Ala Thr Gly Gly Ala Ala Gly Cys Cys Ala Thr Ala 
        595                 600                 605             


Thr Gly Ala Thr Gly Cys Ala Gly Cys Cys Gly Ala Cys Cys Thr Gly 
    610                 615                 620                 


Gly Ala Cys Cys Cys Cys Ala Cys Cys Gly Ala Gly Ala Ala Cys Cys 
625                 630                 635                 640 


Cys Cys Thr Thr Cys Gly Ala Cys Cys Thr Gly Cys Thr Thr Gly Ala 
                645                 650                 655     


Cys Thr Thr Cys Ala Ala Cys Cys Ala Gly Ala Cys Gly Cys Ala Gly 
            660                 665                 670         


Cys Cys Thr Gly Ala Gly Ala Gly Gly Gly Gly Cys Gly Ala Cys Ala 
        675                 680                 685             


Ala Cys Ala Ala Cys Cys Thr Cys Ala Cys Cys Ala Gly Gly Ala Thr 
    690                 695                 700                 


Cys Gly Thr Gly Gly Gly Ala Gly Gly Cys Cys Ala Gly Gly Ala Ala 
705                 710                 715                 720 


Thr Gly Cys Ala Ala Gly Gly Ala Cys Gly Gly Gly Gly Ala Gly Thr 
                725                 730                 735     


Gly Thr Cys Cys Cys Thr Gly Gly Cys Ala Gly Gly Cys Cys Cys Thr 
            740                 745                 750         


Gly Cys Thr Cys Ala Thr Cys Ala Ala Thr Gly Ala Gly Gly Ala Ala 
        755                 760                 765             


Ala Ala Cys Gly Ala Gly Gly Gly Thr Thr Thr Cys Thr Gly Thr Gly 
    770                 775                 780                 


Gly Thr Gly Gly Ala Ala Cys Thr Ala Thr Thr Cys Thr Gly Ala Gly 
785                 790                 795                 800 


Cys Gly Ala Gly Thr Thr Cys Thr Ala Cys Ala Thr Cys Cys Thr Ala 
                805                 810                 815     


Ala Cys Gly Gly Cys Ala Gly Cys Cys Cys Ala Cys Thr Gly Thr Cys 
            820                 825                 830         


Thr Cys Thr Ala Cys Cys Ala Ala Gly Cys Cys Ala Ala Gly Ala Gly 
        835                 840                 845             


Ala Thr Thr Cys Ala Ala Gly Gly Thr Gly Ala Gly Gly Gly Thr Ala 
    850                 855                 860                 


Gly Gly Gly Gly Ala Cys Cys Gly Gly Ala Ala Cys Ala Cys Gly Gly 
865                 870                 875                 880 


Ala Gly Cys Ala Gly Gly Ala Gly Gly Ala Gly Gly Gly Cys Gly Gly 
                885                 890                 895     


Thr Gly Ala Gly Gly Cys Gly Gly Thr Gly Cys Ala Cys Gly Ala Gly 
            900                 905                 910         


Gly Thr Gly Gly Ala Gly Gly Thr Gly Gly Thr Cys Ala Thr Cys Ala 
        915                 920                 925             


Ala Gly Cys Ala Cys Ala Ala Cys Cys Gly Gly Thr Thr Cys Ala Cys 
    930                 935                 940                 


Ala Ala Ala Gly Gly Ala Gly Ala Cys Cys Thr Ala Thr Gly Ala Cys 
945                 950                 955                 960 


Thr Thr Cys Gly Ala Cys Ala Thr Cys Gly Cys Cys Gly Thr Gly Cys 
                965                 970                 975     


Thr Cys Cys Gly Gly Cys Thr Cys Ala Ala Gly Ala Cys Cys Cys Cys 
            980                 985                 990         


Cys Ala Thr Cys Ala Cys Cys Thr  Thr Cys Cys Gly Cys  Ala Thr Gly 
        995                 1000                 1005             


Ala Ala  Cys Gly Thr Gly Gly  Cys Gly Cys Cys Thr  Gly Cys Cys 
    1010                 1015                 1020             


Thr Gly  Cys Cys Thr Cys Cys  Cys Cys Gly Ala Gly  Cys Gly Thr 
    1025                 1030                 1035             


Gly Ala  Cys Thr Gly Gly Gly  Cys Cys Gly Ala Gly  Thr Cys Cys 
    1040                 1045                 1050             


Ala Cys  Gly Cys Thr Gly Ala  Thr Gly Ala Cys Gly  Cys Ala Gly 
    1055                 1060                 1065             


Ala Ala  Gly Ala Cys Gly Gly  Gly Gly Ala Thr Thr  Gly Thr Gly 
    1070                 1075                 1080             


Ala Gly  Cys Gly Gly Cys Thr  Thr Cys Gly Gly Gly  Cys Gly Cys 
    1085                 1090                 1095             


Ala Cys  Cys Cys Ala Cys Gly  Ala Gly Ala Ala Gly  Gly Gly Cys 
    1100                 1105                 1110             


Cys Gly  Gly Cys Ala Gly Thr  Cys Cys Ala Cys Cys  Ala Gly Gly 
    1115                 1120                 1125             


Cys Thr  Cys Ala Ala Gly Ala  Thr Gly Cys Thr Gly  Gly Ala Gly 
    1130                 1135                 1140             


Gly Thr  Gly Cys Cys Cys Thr  Ala Cys Gly Thr Gly  Gly Ala Cys 
    1145                 1150                 1155             


Cys Gly  Cys Ala Ala Cys Ala  Gly Cys Thr Gly Cys  Ala Ala Gly 
    1160                 1165                 1170             


Cys Thr  Gly Thr Cys Cys Ala  Gly Cys Ala Gly Cys  Thr Thr Cys 
    1175                 1180                 1185             


Ala Thr  Cys Ala Thr Cys Ala  Cys Cys Cys Ala Gly  Ala Ala Cys 
    1190                 1195                 1200             


Ala Thr  Gly Thr Thr Cys Thr  Gly Thr Gly Cys Cys  Gly Gly Cys 
    1205                 1210                 1215             


Thr Ala  Cys Gly Ala Cys Ala  Cys Cys Ala Ala Gly  Cys Ala Gly 
    1220                 1225                 1230             


Gly Ala  Gly Gly Ala Thr Gly  Cys Cys Thr Gly Cys  Cys Ala Gly 
    1235                 1240                 1245             


Gly Gly  Gly Gly Ala Cys Ala  Gly Cys Gly Gly Gly  Gly Gly Cys 
    1250                 1255                 1260             


Cys Cys  Gly Cys Ala Cys Gly  Thr Cys Ala Cys Cys  Cys Gly Cys 
    1265                 1270                 1275             


Thr Thr  Cys Ala Ala Gly Gly  Ala Cys Ala Cys Cys  Thr Ala Cys 
    1280                 1285                 1290             


Thr Thr  Cys Gly Thr Gly Ala  Cys Ala Gly Gly Cys  Ala Thr Cys 
    1295                 1300                 1305             


Gly Thr  Cys Ala Gly Cys Thr  Gly Gly Gly Gly Ala  Gly Ala Gly 
    1310                 1315                 1320             


Gly Gly  Cys Thr Gly Thr Gly  Cys Cys Cys Gly Thr  Ala Ala Gly 
    1325                 1330                 1335             


Gly Gly  Gly Ala Ala Gly Thr  Ala Cys Gly Gly Gly  Ala Thr Cys 
    1340                 1345                 1350             


Thr Ala  Cys Ala Cys Cys Ala  Ala Gly Gly Thr Cys  Ala Cys Cys 
    1355                 1360                 1365             


Gly Cys  Cys Thr Thr Cys Cys  Thr Cys Ala Ala Gly  Thr Gly Gly 
    1370                 1375                 1380             


Ala Thr  Cys Gly Ala Cys Ala  Gly Gly Thr Cys Cys  Ala Thr Gly 
    1385                 1390                 1395             


Ala Ala  Ala Ala Cys Cys Ala  Gly Gly Gly Gly Cys  Thr Thr Gly 
    1400                 1405                 1410             


Cys Cys  Cys Ala Ala Gly Gly  Cys Cys Ala Ala Gly  Ala Gly Cys 
    1415                 1420                 1425             


Cys Ala  Thr Gly Cys Cys Cys  Cys Gly Gly Ala Gly  Gly Thr Cys 
    1430                 1435                 1440             


Ala Thr  Ala Ala Cys Gly Thr  Cys Cys Thr Cys Thr  Cys Cys Ala 
    1445                 1450                 1455             


Thr Thr  Ala Ala Ala Gly 
    1460                 


<210>  421
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  421

Ser Val Thr Val His Ser Ser Glu Pro Glu Val Arg Ile Pro Glu Asn 
1               5                   10                  15      


Asn Pro Val Lys Leu Ser Cys Ala Tyr Ser Gly Phe Ser Ser Pro Arg 
            20                  25                  30          


Val Glu Trp Lys Phe Asp Gln Gly Asp Thr Thr Arg Leu Val Cys Tyr 
        35                  40                  45              


Asn Asn Lys Ile Thr Ala Ser Tyr Glu Asp Arg Val Thr Phe Leu Pro 
    50                  55                  60                  


Thr Gly Ile Thr Phe Lys Ser Val Thr Arg Glu Asp Thr Gly Thr Tyr 
65                  70                  75                  80  


Thr Cys Met Val Ser Glu Glu Gly Gly Asn Ser Tyr Gly Glu Val Lys 
                85                  90                  95      


Val Lys Leu Ile Val Leu Val Pro Pro Ser Lys Pro Thr Val Asn Ile 
            100                 105                 110         


Pro Ser Ser Ala Thr Ile Gly Asn Arg Ala Val Leu Thr Cys Ser Glu 
        115                 120                 125             


Gln Asp Gly Ser Pro Pro Ser Glu Tyr Thr Trp Phe Lys Asp Gly Ile 
    130                 135                 140                 


Val Met Pro Thr Asn Pro Lys Ser Thr Arg Ala Phe Ser Asn Ser Ser 
145                 150                 155                 160 


Tyr Val Leu Asn Pro Thr Thr Gly Glu Leu Val Phe Asp Pro Leu Ser 
                165                 170                 175     


Ala Ser Asp Thr Gly Glu Tyr Ser Cys Glu Ala Arg Asn Gly Tyr Gly 
            180                 185                 190         


Thr Pro Met Thr Ser Asn Ala Val Arg Met Glu Ala Val Glu Arg Asn 
        195                 200                 205             


Val Gly Val 
    210     


<210>  422
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  422

Val Val Gly Gly Leu Val Ala Leu Arg Gly Ala His Pro Tyr Ile Ala 
1               5                   10                  15      


Ala Leu Tyr Trp Gly His Ser Phe Cys Ala Gly Ser Leu Ile Ala Pro 
            20                  25                  30          


Cys Trp Val Leu Thr Ala Ala His Cys Leu Gln Asp Arg Pro Ala Pro 
        35                  40                  45              


Glu Asp Leu Thr Val Val Leu Gly Gln Glu Arg Arg Asn His Ser Cys 
    50                  55                  60                  


Glu Pro Cys Gln Thr Leu Ala Val Arg Ser Tyr Arg Leu His Glu Ala 
65                  70                  75                  80  


Phe Ser Pro Val Ser Tyr Gln His Asp Leu Ala Leu Leu Arg Leu Gln 
                85                  90                  95      


Glu Asp Ala Asp Gly Ser Cys Ala Leu Leu Ser Pro Tyr Val Gln Pro 
            100                 105                 110         


Val Cys Leu Pro Ser Gly Ala Ala Arg Pro Ser Glu Thr Thr Leu Cys 
        115                 120                 125             


Gln Val Ala Gly Trp Gly His Gln Phe Glu Gly Ala Glu Glu Tyr Ala 
    130                 135                 140                 


Ser Phe Leu Gln Glu Ala Gln Val Pro Phe Leu Ser Leu Glu Arg Cys 
145                 150                 155                 160 


Ser Ala Pro Asp Val His Gly Ser Ser Ile Leu Pro Gly Met Leu Cys 
                165                 170                 175     


Ala Gly Phe Leu Glu Gly Gly Thr Asp Ala Cys Gln Gly Asp Ser Gly 
            180                 185                 190         


Gly Pro Leu Val Cys Glu Asp Gln Ala Ala Glu Arg Arg Leu Thr Leu 
        195                 200                 205             


Gln Gly Ile Ile Ser Trp Gly Ser Gly Cys Gly Asp Arg Asn Lys Pro 
    210                 215                 220                 


Gly Val Tyr Thr Asp Val Ala Tyr Tyr Leu Ala Trp Ile Arg Glu His 
225                 230                 235                 240 


Thr Val Ser 
            


<210>  423
<211>  694
<212>  PRT
<213>  Homo Sapiens

<400>  423

Gly Val Asn Leu Gln Glu Phe Leu Asn Val Thr Ser Val His Leu Phe 
1               5                   10                  15      


Lys Glu Arg Trp Asp Thr Asn Lys Val Asp His His Thr Asp Lys Tyr 
            20                  25                  30          


Glu Asn Asn Lys Leu Ile Val Arg Arg Gly Gln Ser Phe Tyr Val Gln 
        35                  40                  45              


Ile Asp Phe Ser Arg Pro Tyr Asp Pro Arg Arg Asp Leu Phe Arg Val 
    50                  55                  60                  


Glu Tyr Val Ile Gly Arg Tyr Pro Gln Glu Asn Lys Gly Thr Tyr Ile 
65                  70                  75                  80  


Pro Val Pro Ile Val Ser Glu Leu Gln Ser Gly Lys Trp Gly Ala Lys 
                85                  90                  95      


Ile Val Met Arg Glu Asp Arg Ser Val Arg Leu Ser Ile Gln Ser Ser 
            100                 105                 110         


Pro Lys Cys Ile Val Gly Lys Phe Arg Met Tyr Val Ala Val Trp Thr 
        115                 120                 125             


Pro Tyr Gly Val Leu Arg Thr Ser Arg Asn Pro Glu Thr Asp Thr Tyr 
    130                 135                 140                 


Ile Leu Phe Asn Pro Trp Cys Glu Asp Asp Ala Val Tyr Leu Asp Asn 
145                 150                 155                 160 


Glu Lys Glu Arg Glu Glu Tyr Val Leu Asn Asp Ile Gly Val Ile Phe 
                165                 170                 175     


Tyr Gly Glu Val Asn Asp Ile Lys Thr Arg Ser Trp Ser Tyr Gly Gln 
            180                 185                 190         


Phe Glu Asp Gly Ile Leu Asp Thr Cys Leu Tyr Val Met Asp Arg Ala 
        195                 200                 205             


Gln Met Asp Leu Ser Gly Arg Gly Asn Pro Ile Lys Val Ser Arg Val 
    210                 215                 220                 


Gly Ser Ala Met Val Asn Ala Lys Asp Asp Glu Gly Val Leu Val Gly 
225                 230                 235                 240 


Ser Trp Asp Asn Ile Tyr Ala Tyr Gly Val Pro Pro Ser Ala Trp Thr 
                245                 250                 255     


Gly Ser Val Asp Ile Leu Leu Glu Tyr Arg Ser Ser Glu Asn Pro Val 
            260                 265                 270         


Arg Tyr Gly Gln Cys Trp Val Phe Ala Gly Val Phe Asn Thr Phe Leu 
        275                 280                 285             


Arg Cys Leu Gly Ile Pro Ala Arg Ile Val Thr Asn Tyr Phe Ser Ala 
    290                 295                 300                 


His Asp Asn Asp Ala Asn Leu Gln Met Asp Ile Phe Leu Glu Glu Asp 
305                 310                 315                 320 


Gly Asn Val Asn Ser Lys Leu Thr Lys Asp Ser Val Trp Asn Tyr His 
                325                 330                 335     


Cys Trp Asn Glu Ala Trp Met Thr Arg Pro Asp Leu Pro Val Gly Phe 
            340                 345                 350         


Gly Gly Trp Gln Ala Val Asp Ser Thr Pro Gln Glu Asn Ser Asp Gly 
        355                 360                 365             


Met Tyr Arg Cys Gly Pro Ala Ser Val Gln Ala Ile Lys His Gly His 
    370                 375                 380                 


Val Cys Phe Gln Phe Asp Ala Pro Phe Val Phe Ala Glu Val Asn Ser 
385                 390                 395                 400 


Asp Leu Ile Tyr Ile Thr Ala Lys Lys Asp Gly Thr His Val Val Glu 
                405                 410                 415     


Asn Val Asp Ala Thr His Ile Gly Lys Leu Ile Val Thr Lys Gln Ile 
            420                 425                 430         


Gly Gly Asp Gly Met Met Asp Ile Thr Asp Thr Tyr Lys Phe Gln Glu 
        435                 440                 445             


Gly Gln Glu Glu Glu Arg Leu Ala Leu Glu Thr Ala Leu Met Tyr Gly 
    450                 455                 460                 


Ala Lys Lys Pro Leu Asn Thr Glu Gly Val Met Lys Ser Arg Ser Asn 
465                 470                 475                 480 


Val Asp Met Asp Phe Glu Val Glu Asn Ala Val Leu Gly Lys Asp Phe 
                485                 490                 495     


Lys Leu Ser Ile Thr Phe Arg Asn Asn Ser His Asn Arg Tyr Thr Ile 
            500                 505                 510         


Thr Ala Tyr Leu Ser Ala Asn Ile Thr Phe Tyr Thr Gly Val Pro Lys 
        515                 520                 525             


Ala Glu Phe Lys Lys Glu Thr Phe Asp Val Thr Leu Glu Pro Leu Ser 
    530                 535                 540                 


Phe Lys Lys Glu Ala Val Leu Ile Gln Ala Gly Glu Tyr Met Gly Gln 
545                 550                 555                 560 


Leu Leu Glu Gln Ala Ser Leu His Phe Phe Val Thr Ala Arg Ile Asn 
                565                 570                 575     


Glu Thr Arg Asp Val Leu Ala Lys Gln Lys Ser Thr Val Leu Thr Ile 
            580                 585                 590         


Pro Glu Ile Ile Ile Lys Val Arg Gly Thr Gln Val Val Gly Ser Asp 
        595                 600                 605             


Met Thr Val Ile Val Glu Phe Thr Asn Pro Leu Lys Glu Thr Leu Arg 
    610                 615                 620                 


Asn Val Trp Val His Leu Asp Gly Pro Gly Val Thr Arg Pro Met Lys 
625                 630                 635                 640 


Lys Met Phe Arg Glu Ile Arg Pro Asn Ser Thr Val Gln Trp Glu Glu 
                645                 650                 655     


Val Cys Arg Pro Trp Val Ser Gly His Arg Lys Leu Ile Ala Ser Met 
            660                 665                 670         


Ser Ser Asp Ser Leu Arg His Val Tyr Gly Glu Leu Asp Val Gln Ile 
        675                 680                 685             


Gln Arg Arg Pro Ser Met 
    690                 


<210>  424
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  424

Ser Gly Thr Thr Asn Thr Val Ala Ala Tyr Asn Leu Thr Trp Lys Ser 
1               5                   10                  15      


Thr Asn Phe Lys Thr Ile Leu Glu Trp Glu Pro Lys Pro Val Asn Gln 
            20                  25                  30          


Val Tyr Thr Val Gln Ile Ser Thr Lys Ser Gly Asp Trp Lys Ser Lys 
        35                  40                  45              


Cys Phe Tyr Thr Thr Asp Thr Glu Cys Asp Leu Thr Asp Glu Ile Val 
    50                  55                  60                  


Lys Asp Val Lys Gln Thr Tyr Leu Ala Arg Val Phe Ser Tyr Pro Ala 
65                  70                  75                  80  


Gly Asn Val Glu Ser Thr Gly Ser Ala Gly Glu Pro Leu Tyr Glu Asn 
                85                  90                  95      


Ser Pro Glu Phe Thr Pro Tyr Leu Glu Thr Asn Leu Gly Gln Pro Thr 
            100                 105                 110         


Ile Gln Ser Phe Glu Gln Val Gly Thr Lys Val Asn Val Thr Val Glu 
        115                 120                 125             


Asp Glu Arg Thr Leu Val Arg Arg Asn Asn Thr Phe Leu Ser Leu Arg 
    130                 135                 140                 


Asp Val Phe Gly Lys Asp Leu Ile Tyr Thr Leu Tyr Tyr Trp Lys Ser 
145                 150                 155                 160 


Ser Ser Ser Gly Lys Lys Thr Ala Lys Thr Asn Thr Asn Glu Phe Leu 
                165                 170                 175     


Ile Asp Val Asp Lys Gly Glu Asn Tyr Cys Phe Ser Val Gln Ala Val 
            180                 185                 190         


Ile Pro Ser Arg Thr Val Asn Arg Lys Ser Thr Asp Ser Pro Val Glu 
        195                 200                 205             


Cys Met Gly Gln Glu Lys Gly Glu Phe Arg Glu 
    210                 215                 


<210>  425
<211>  406
<212>  PRT
<213>  Homo Sapiens

<400>  425

Ala Asn Ala Phe Leu Glu Glu Leu Arg Pro Gly Ser Leu Glu Arg Glu 
1               5                   10                  15      


Cys Lys Glu Glu Gln Cys Ser Phe Glu Glu Ala Arg Glu Ile Phe Lys 
            20                  25                  30          


Asp Ala Glu Arg Thr Lys Leu Phe Trp Ile Ser Tyr Ser Asp Gly Asp 
        35                  40                  45              


Gln Cys Ala Ser Ser Pro Cys Gln Asn Gly Gly Ser Cys Lys Asp Gln 
    50                  55                  60                  


Leu Gln Ser Tyr Ile Cys Phe Cys Leu Pro Ala Phe Glu Gly Arg Asn 
65                  70                  75                  80  


Cys Glu Thr His Lys Asp Asp Gln Leu Ile Cys Val Asn Glu Asn Gly 
                85                  90                  95      


Gly Cys Glu Gln Tyr Cys Ser Asp His Thr Gly Thr Lys Arg Ser Cys 
            100                 105                 110         


Arg Cys His Glu Gly Tyr Ser Leu Leu Ala Asp Gly Val Ser Cys Thr 
        115                 120                 125             


Pro Thr Val Glu Tyr Pro Cys Gly Lys Ile Pro Ile Leu Glu Lys Arg 
    130                 135                 140                 


Asn Ala Ser Lys Pro Gln Gly Arg Ile Val Gly Gly Lys Val Cys Pro 
145                 150                 155                 160 


Lys Gly Glu Cys Pro Trp Gln Val Leu Leu Leu Val Asn Gly Ala Gln 
                165                 170                 175     


Leu Cys Gly Gly Thr Leu Ile Asn Thr Ile Trp Val Val Ser Ala Ala 
            180                 185                 190         


His Cys Phe Asp Lys Ile Lys Asn Trp Arg Asn Leu Ile Ala Val Leu 
        195                 200                 205             


Gly Glu His Asp Leu Ser Glu His Asp Gly Asp Glu Gln Ser Arg Arg 
    210                 215                 220                 


Val Ala Gln Val Ile Ile Pro Ser Thr Tyr Val Pro Gly Thr Thr Asn 
225                 230                 235                 240 


His Asp Ile Ala Leu Leu Arg Leu His Gln Pro Val Val Leu Thr Asp 
                245                 250                 255     


His Val Val Pro Leu Cys Leu Pro Glu Arg Thr Phe Ser Glu Arg Thr 
            260                 265                 270         


Leu Ala Phe Val Arg Phe Ser Leu Val Ser Gly Trp Gly Gln Leu Leu 
        275                 280                 285             


Asp Arg Gly Ala Thr Ala Leu Glu Leu Met Val Leu Asn Val Pro Arg 
    290                 295                 300                 


Leu Met Thr Gln Asp Cys Leu Gln Gln Ser Arg Lys Val Gly Asp Ser 
305                 310                 315                 320 


Pro Asn Ile Thr Glu Tyr Met Phe Cys Ala Gly Tyr Ser Asp Gly Ser 
                325                 330                 335     


Lys Asp Ser Cys Lys Gly Asp Ser Gly Gly Pro His Ala Thr His Tyr 
            340                 345                 350         


Arg Gly Thr Trp Tyr Leu Thr Gly Ile Val Ser Trp Gly Gln Gly Cys 
        355                 360                 365             


Ala Thr Val Gly His Phe Gly Val Tyr Thr Arg Val Ser Gln Tyr Ile 
    370                 375                 380                 


Glu Trp Leu Gln Lys Leu Met Arg Ser Glu Pro Arg Pro Gly Val Leu 
385                 390                 395                 400 


Leu Arg Ala Pro Phe Pro 
                405     


<210>  426
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  426

Tyr Asn Ser Gly Lys Leu Glu Glu Phe Val Gln Gly Asn Leu Glu Arg 
1               5                   10                  15      


Glu Cys Met Glu Glu Lys Cys Ser Phe Glu Glu Ala Arg Glu Val Phe 
            20                  25                  30          


Glu Asn Thr Glu Arg Thr Thr Glu Phe Trp Lys Gln Tyr Val Asp Gly 
        35                  40                  45              


Asp Gln Cys Glu Ser Asn Pro Cys Leu Asn Gly Gly Ser Cys Lys Asp 
    50                  55                  60                  


Asp Ile Asn Ser Tyr Glu Cys Trp Cys Pro Phe Gly Phe Glu Gly Lys 
65                  70                  75                  80  


Asn Cys Glu Leu Asp Val Thr Cys Asn Ile Lys Asn Gly Arg Cys Glu 
                85                  90                  95      


Gln Phe Cys Lys Asn Ser Ala Asp Asn Lys Val Val Cys Ser Cys Thr 
            100                 105                 110         


Glu Gly Tyr Arg Leu Ala Glu Asn Gln Lys Ser Cys Glu Pro Ala Val 
        115                 120                 125             


Pro Phe Pro Cys Gly Arg Val Ser Val Ser Gln Thr Ser Lys Leu Thr 
    130                 135                 140                 


Arg Ala Glu Thr Val Phe Pro Asp Val Asp Tyr Val Asn Ser Thr Glu 
145                 150                 155                 160 


Ala Glu Thr Ile Leu Asp Asn Ile Thr Gln Ser Thr Gln Ser Phe Asn 
                165                 170                 175     


Asp Phe Thr Arg Val Val Gly Gly Glu Asp Ala Lys Pro Gly Gln Phe 
            180                 185                 190         


Pro Trp Gln Val Val Leu Asn Gly Lys Val Asp Ala Phe Cys Gly Gly 
        195                 200                 205             


Ser Ile Val Asn Glu Lys Trp Ile Val Thr Ala Ala His Cys Val Glu 
    210                 215                 220                 


Thr Gly Val Lys Ile Thr Val Val Ala Gly Glu His Asn Ile Glu Glu 
225                 230                 235                 240 


Thr Glu His Thr Glu Gln Lys Arg Asn Val Ile Arg Ile Ile Pro His 
                245                 250                 255     


His Asn Tyr Asn Ala Ala Ile Asn Lys Tyr Asn His Asp Ile Ala Leu 
            260                 265                 270         


Leu Glu Leu Asp Glu Pro Leu Val Leu Asn Ser Tyr Val Thr Pro Ile 
        275                 280                 285             


Cys Ile Ala Asp Lys Glu Tyr Thr Asn Ile Phe Leu Lys Phe Gly Ser 
    290                 295                 300                 


Gly Tyr Val Ser Gly Trp Gly Arg Val Phe His Lys Gly Arg Ser Ala 
305                 310                 315                 320 


Leu Val Leu Gln Tyr Leu Arg Val Pro Leu Val Asp Arg Ala Thr Cys 
                325                 330                 335     


Leu Arg Ser Thr Lys Phe Thr Ile Tyr Asn Asn Met Phe Cys Ala Gly 
            340                 345                 350         


Phe His Glu Gly Gly Arg Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro 
        355                 360                 365             


His Val Thr Glu Val Glu Gly Thr Ser Phe Leu Thr Gly Ile Ile Ser 
    370                 375                 380                 


Trp Gly Glu Glu Cys Ala Met Lys Gly Lys Tyr Gly Ile Tyr Thr Lys 
385                 390                 395                 400 


Val Ser Arg Tyr Val Asn Trp Ile Lys Glu Lys Thr Lys Leu Thr 
                405                 410                 415 


<210>  427
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  427

Ser Pro Glu Pro Gly Ala Pro Ser Arg Ser Arg Ala Arg Arg Glu Pro 
1               5                   10                  15      


Pro Pro Gly Asn Glu Leu Pro Arg Gly Pro Gly Glu Ser Arg Ala Gly 
            20                  25                  30          


Pro Ala Ala Arg Pro Pro Glu Pro Thr Ala Glu Arg Ala His Ser Val 
        35                  40                  45              


Asp Pro Arg Asp Ala Trp Met Leu Phe Val Arg Gln Ser Asp Lys Gly 
    50                  55                  60                  


Val Asn Gly Lys Lys Arg Ser Arg Gly Lys Ala Lys Lys Leu Lys Phe 
65                  70                  75                  80  


Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly Pro Gln Gly Pro Pro Gly 
                85                  90                  95      


Pro Ile Ile Pro Pro Glu Ala Leu Leu Lys Glu Phe Gln Leu Leu Leu 
            100                 105                 110         


Lys Gly Ala Val Arg Gln Arg Glu Arg Ala Glu Pro Glu Pro Cys Thr 
        115                 120                 125             


Cys Gly Pro Ala Gly Pro Val Ala Ala Ser Leu Ala Pro Val Ser Ala 
    130                 135                 140                 


Thr Ala Gly Glu Asp Asp Asp Asp Val Val Gly Asp Val Leu Ala Leu 
145                 150                 155                 160 


Leu Ala Ala Pro Leu Ala Pro Gly Pro Arg Ala Pro Arg Val Glu Ala 
                165                 170                 175     


Ala Phe Leu Cys Arg Leu Arg Arg Asp Ala Leu Val Glu Arg Arg Ala 
            180                 185                 190         


Leu His Glu Leu Gly Val Tyr Tyr Leu Pro Asp Ala Glu Gly Ala Phe 
        195                 200                 205             


Arg Arg Gly Pro Gly Leu Asn Leu Thr Ser Gly Gln Tyr Arg Ala Pro 
    210                 215                 220                 


Val Ala Gly Phe Tyr Ala Leu Ala Ala Thr Leu His Val Ala Leu Gly 
225                 230                 235                 240 


Glu Pro Pro Arg Arg Gly Pro Pro Arg Pro Arg Asp His Leu Arg Leu 
                245                 250                 255     


Leu Ile Cys Ile Gln Ser Arg Cys Gln Arg Asn Ala Ser Leu Glu Ala 
            260                 265                 270         


Ile Met Gly Leu Glu Ser Ser Ser Glu Leu Phe Thr Ile Ser Val Asn 
        275                 280                 285             


Gly Val Leu Tyr Leu Gln Met Gly Gln Trp Thr Ser Val Phe Leu Asp 
    290                 295                 300                 


Asn Ala Ser Gly Cys Ser Leu Thr Val Arg Ser Gly Ser His Phe Ser 
305                 310                 315                 320 


Ala Val Leu Leu Gly Val 
                325     


<210>  428
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  428

Lys Thr Leu Arg Glu Pro Gly Ala Gly Ala Gln Glu Val Thr Leu Lys 
1               5                   10                  15      


Val His Ile Ser Asp Ala Ser Thr His Gln Pro Val Ala Asp Ala Leu 
            20                  25                  30          


Ile Glu Ile Phe Thr Asn Gln Ala Ser Ile Ala Ser Gly Thr Ser Gly 
        35                  40                  45              


Thr Asp Gly Val Ala Phe Ile Lys Phe Gln Tyr Lys Leu Gly Ser Gln 
    50                  55                  60                  


Leu Ile Val Thr Ala Ser Lys His Ala Tyr Val Pro Asn Ser Ala Pro 
65                  70                  75                  80  


Trp Lys Pro Ile Arg Leu Pro Val Phe Ser Ser Leu Ser Leu Gly Leu 
                85                  90                  95      


Leu Pro Glu Arg Ser Ala Thr Leu Met Val Tyr Glu Asp Val Val Gln 
            100                 105                 110         


Ile Val Ser Gly Phe Gln Gly Ala Arg Pro Gln Pro Arg Val His Phe 
        115                 120                 125             


Gln Arg Arg Ala Leu Arg Leu Pro Glu Asn Thr Ser Tyr Ser Asp Leu 
    130                 135                 140                 


Thr Ala Phe Leu Thr Ala Ala Ser Ser Pro Ser Glu Val Asp Ser Phe 
145                 150                 155                 160 


Pro Tyr Leu Arg Gly Leu Asp Gly Asn Gly Thr Gly Asn Ser Thr Arg 
                165                 170                 175     


His Asp Leu Thr Pro Val Thr Ala Val Ser Val His Leu Leu Ser Ser 
            180                 185                 190         


Asn Gly Thr Pro Val Leu Val Asp Gly Pro Ile Tyr Val Thr Val Pro 
        195                 200                 205             


Leu Ala Thr Gln Ser Ser Leu Arg His Asn Ala Tyr Val Ala Ala Trp 
    210                 215                 220                 


Arg Phe Asp Gln Lys Leu Gly Thr Trp Leu Lys Ser Gly Leu Gly Leu 
225                 230                 235                 240 


Val His Gln Glu Gly Ser Gln Leu Thr Trp Thr Tyr Ile Ala Pro Gln 
                245                 250                 255     


Leu Gly Tyr Trp Val Ala Ala Met Ser Pro Pro Ile Pro Gly Pro Val 
            260                 265                 270         


Val Thr Gln Asp Ile Thr Thr Tyr His Thr 
        275                 280         


<210>  429
<211>  359
<212>  PRT
<213>  Homo Sapiens

<400>  429

Phe Glu Ile Val Glu Lys Glu Asn Ile Phe Gln Arg Thr Pro Cys Pro 
1               5                   10                  15      


Ala Phe Leu Met Phe Glu Asn Ala Ala Tyr Leu Ala Asp Met Ser Phe 
            20                  25                  30          


Glu Leu Pro Cys His Cys Lys Pro Glu Glu Val Pro Ala Val Val Trp 
        35                  40                  45              


Phe Tyr Gln Lys His Leu Gly Ser Ser His Thr Lys Val Leu Thr Asp 
    50                  55                  60                  


Phe Asp Gly Arg Val Leu Thr Glu Ala Ala Gln Val Arg Val Gly Ser 
65                  70                  75                  80  


Asp Met Leu Thr Arg Phe Ser Ile Arg Met Phe Ser Leu Leu Val Phe 
                85                  90                  95      


Arg Ala Gln Ser Glu Asp Ser Gly Leu Tyr Phe Cys Gly Thr Arg Lys 
            100                 105                 110         


Gly Asp Tyr Phe Tyr Ala Tyr Asp Val Asp Ile Gln Asn Ser Glu Gly 
        115                 120                 125             


Met Val Ala Thr Phe Gln Asp Lys Gly Gln Glu Pro Phe Ala Asp Glu 
    130                 135                 140                 


Tyr Tyr Gly His Leu His Val Phe Thr Thr Phe Trp Glu Trp Thr Pro 
145                 150                 155                 160 


Cys Asp Arg Cys Gly Val Arg Gly Glu Gln Trp Arg Ile Gly Leu Cys 
                165                 170                 175     


Tyr Leu Gln Ser Pro Asp Leu Ser Pro Arg Tyr Leu Lys Ala Val Pro 
            180                 185                 190         


Asp Val Val Ser Cys Gly Ser Arg Ala Val Pro Arg Lys Leu Arg Thr 
        195                 200                 205             


Lys Ala Arg Asp His Thr Pro Glu Val Leu Val Arg Ser Cys Leu Val 
    210                 215                 220                 


Pro Cys Glu Lys Thr Lys Thr Ile Arg Glu Gly Val Leu Ala Ile Ile 
225                 230                 235                 240 


Asn Tyr Val Ser Lys Val Gly Ser Arg Pro Trp Val Pro Gln Val Pro 
                245                 250                 255     


Ile Gln Phe His Gln Gln Arg Leu Gly His Gly Leu Ile Ile Ser Cys 
            260                 265                 270         


Pro Gly Ala Arg Pro Glu His Ala Val Ala Trp Asp Lys Asp Arg Gln 
        275                 280                 285             


His Leu Tyr Arg Thr Gln Tyr Leu Lys Gly Val Asn Arg Ser Met Arg 
    290                 295                 300                 


Val Phe Ile Asp His Gly Asn Gln Leu His Ile Arg Phe Thr Gln Leu 
305                 310                 315                 320 


Asp Asp Arg Gly Ile Tyr Tyr Cys Trp Arg Gln Gly Val Leu Val Ala 
                325                 330                 335     


Gly Phe Arg Leu Gly Val Thr Ser His Gly His Tyr Pro Ala Ser Phe 
            340                 345                 350         


Ser Asp Pro Glu Thr Arg Ser 
        355                 


<210>  430
<211>  318
<212>  PRT
<213>  Homo Sapiens

<400>  430

Phe Tyr Phe Ser Ile Ser Cys Pro Ser Gly Lys Gln Cys Gln Gln Ala 
1               5                   10                  15      


Leu Leu Ser Gly Asn Asp Ile Leu Leu Tyr Cys Asn Ser Ser Gly Ala 
            20                  25                  30          


His Trp Tyr Tyr Leu Phe Thr Gln Gly Lys Lys Gly Arg Leu Thr Ser 
        35                  40                  45              


Leu Thr Asn Ile Ser Asn Met Glu Ile Met Pro Glu Gly Ser Leu Leu 
    50                  55                  60                  


Ile Lys Asp Pro Leu Pro Ser Gln Thr Gly Leu Tyr His Cys Trp Asn 
65                  70                  75                  80  


Lys Asn Gly Arg Gln Val Val Gln Tyr Glu Ile Asp Phe Gln Asp Val 
                85                  90                  95      


Thr Thr Leu His Ile Thr His Lys Asp Leu Gly Gln Arg Pro Leu Gln 
            100                 105                 110         


Asn Glu Thr Leu His Leu Gly Ser Lys Gln Leu Ile Phe Thr Trp Trp 
        115                 120                 125             


Glu Pro Trp Gln Asp Cys Asn Arg Cys Glu Glu Pro Gly Glu Arg Lys 
    130                 135                 140                 


Arg Leu Gly Tyr Arg Tyr Ile Glu Glu Pro Leu Glu Glu Ala Met Pro 
145                 150                 155                 160 


Cys Trp Leu Tyr Leu Gly Glu Val Leu Val Trp Ser Ser Arg Leu Arg 
                165                 170                 175     


Pro Glu Leu Gln Val Glu Ala Cys His Val Gln Cys Thr Asn Asn Thr 
            180                 185                 190         


Gln Leu Arg Val Asp Tyr Val Ile Phe Asp Asn Phe Arg Leu Asp Glu 
        195                 200                 205             


Lys Thr Glu Phe Val Trp Leu Asp Cys Pro Leu Gly Ser Met Tyr Arg 
    210                 215                 220                 


Pro Val Asn Trp Arg Ala Asn Asp Thr Pro Leu Thr Trp Glu Ser Gln 
225                 230                 235                 240 


Leu Ser Gly Gln Asp Phe Thr Thr Phe Leu Asp Pro Ser Thr Gly Gly 
                245                 250                 255     


Arg Gln Leu Gln Val Phe Gln Pro Ala Val Tyr Lys Cys Phe Val Gln 
            260                 265                 270         


Gln Glu Leu Val Ala Gln Phe Lys Pro Ala Ala Ser Leu Glu Thr Leu 
        275                 280                 285             


Glu Ala Gln Trp Arg Glu Asn Asp Ala Gln Trp Arg Glu Ala Arg Lys 
    290                 295                 300                 


Ala Leu Arg Gly Arg Ala Asp Ser Val Leu Lys Gly Leu Lys 
305                 310                 315             


<210>  431
<211>  492
<212>  PRT
<213>  Homo Sapiens

<400>  431

Asp Phe Ser Ser Asp Pro Ser Ser Asn Leu Ser Ser His Ser Leu Glu 
1               5                   10                  15      


Lys Leu Pro Pro Ala Ala Glu Pro Ala Glu Arg Ala Leu Arg Gly Arg 
            20                  25                  30          


Asp Pro Gly Ala Leu Arg Pro His Asp Pro Ala His Arg Pro Leu Leu 
        35                  40                  45              


Arg Asp Pro Gly Pro Arg Arg Ser Glu Ser Pro Pro Gly Pro Gly Gly 
    50                  55                  60                  


Asp Ala Ser Leu Leu Ala Arg Leu Phe Glu His Pro Leu Tyr Arg Val 
65                  70                  75                  80  


Ala Val Pro Pro Leu Thr Glu Glu Asp Val Leu Phe Asn Val Asn Ser 
                85                  90                  95      


Asp Thr Arg Leu Ser Pro Lys Ala Ala Glu Asn Pro Asp Trp Pro His 
            100                 105                 110         


Ala Gly Ala Glu Gly Ala Glu Phe Leu Ser Pro Gly Glu Ala Ala Val 
        115                 120                 125             


Asp Ser Tyr Pro Asn Trp Leu Lys Phe His Ile Gly Ile Asn Arg Tyr 
    130                 135                 140                 


Glu Leu Tyr Ser Arg His Asn Pro Ala Ile Glu Ala Leu Leu His Asp 
145                 150                 155                 160 


Leu Ser Ser Gln Arg Ile Thr Ser Val Ala Met Lys Ser Gly Gly Thr 
                165                 170                 175     


Gln Leu Lys Leu Ile Met Thr Phe Gln Asn Tyr Gly Gln Ala Leu Phe 
            180                 185                 190         


Lys Pro Met Lys Gln Thr Arg Glu Gln Glu Thr Pro Pro Asp Phe Phe 
        195                 200                 205             


Tyr Phe Ser Asp Tyr Glu Arg His Asn Ala Glu Ile Ala Ala Phe His 
    210                 215                 220                 


Leu Asp Arg Ile Leu Asp Phe Arg Arg Val Pro Pro Val Ala Gly Arg 
225                 230                 235                 240 


Met Val Asn Met Thr Lys Glu Ile Arg Asp Val Thr Arg Asp Lys Lys 
                245                 250                 255     


Leu Trp Arg Thr Phe Phe Ile Ser Pro Ala Asn Asn Ile Cys Phe Tyr 
            260                 265                 270         


Gly Glu Cys Ser Tyr Tyr Cys Ser Thr Glu His Ala Leu Cys Gly Lys 
        275                 280                 285             


Pro Asp Gln Ile Glu Gly Ser Leu Ala Ala Phe Leu Pro Asp Leu Ser 
    290                 295                 300                 


Leu Ala Lys Arg Lys Thr Trp Arg Asn Pro Trp Arg Arg Ser Tyr His 
305                 310                 315                 320 


Lys Arg Lys Lys Ala Glu Trp Glu Val Asp Pro Asp Tyr Cys Glu Glu 
                325                 330                 335     


Val Lys Gln Thr Pro Pro Tyr Asp Ser Ser His Arg Ile Leu Asp Val 
            340                 345                 350         


Met Asp Met Thr Ile Phe Asp Phe Leu Met Gly Asn Met Asp Arg His 
        355                 360                 365             


His Tyr Glu Thr Phe Glu Lys Phe Gly Asn Glu Thr Phe Ile Ile His 
    370                 375                 380                 


Leu Asp Asn Gly Arg Gly Phe Gly Lys Tyr Ser His Asp Glu Leu Ser 
385                 390                 395                 400 


Ile Leu Val Pro Leu Gln Gln Cys Cys Arg Ile Arg Lys Ser Thr Tyr 
                405                 410                 415     


Leu Arg Leu Gln Leu Leu Ala Lys Glu Glu Tyr Lys Leu Ser Leu Leu 
            420                 425                 430         


Met Ala Glu Ser Leu Arg Gly Asp Gln Val Ala Pro Val Leu Tyr Gln 
        435                 440                 445             


Pro His Leu Glu Ala Leu Asp Arg Arg Leu Arg Val Val Leu Lys Ala 
    450                 455                 460                 


Val Arg Asp Cys Val Glu Arg Asn Gly Leu His Ser Val Val Asp Asp 
465                 470                 475                 480 


Asp Leu Asp Thr Glu His Arg Ala Ala Ser Ala Arg 
                485                 490         


<210>  432
<211>  276
<212>  PRT
<213>  Homo Sapiens

<400>  432

Gly Thr Ala Thr Arg Phe Ser Gly Gln Ser Tyr Val Arg Tyr Arg Ala 
1               5                   10                  15      


Pro Ala Ala Arg Asn Trp His Ile His Phe Tyr Leu Lys Thr Leu Gln 
            20                  25                  30          


Pro Gln Ala Ile Leu Leu Phe Thr Asn Glu Thr Ala Ser Val Ser Leu 
        35                  40                  45              


Lys Leu Ala Ser Gly Val Pro Gln Leu Glu Tyr His Cys Leu Gly Gly 
    50                  55                  60                  


Phe Tyr Gly Asn Leu Ser Ser Gln Arg His Val Asn Asp His Glu Trp 
65                  70                  75                  80  


His Ser Ile Leu Val Glu Glu Met Asp Ala Ser Ile Arg Leu Met Val 
                85                  90                  95      


Asp Ser Met Gly Asn Thr Ser Leu Val Val Pro Glu Asn Cys Arg Gly 
            100                 105                 110         


Leu Arg Pro Glu Arg His Leu Leu Leu Gly Gly Leu Ile Leu Leu His 
        115                 120                 125             


Ser Ser Ser Asn Val Ser Gln Gly Phe Glu Gly Cys Leu Asp Ala Val 
    130                 135                 140                 


Val Val Asn Glu Glu Ala Leu Asp Leu Leu Ala Pro Gly Lys Thr Val 
145                 150                 155                 160 


Ala Gly Leu Leu Glu Thr Gln Ala Leu Thr Gln Cys Cys Leu His Ser 
                165                 170                 175     


Asp Tyr Cys Ser Gln Asn Thr Cys Leu Asn Gly Gly Lys Cys Ser Trp 
            180                 185                 190         


Thr His Gly Ala Gly Tyr Val Cys Lys Cys Pro Pro Gln Phe Ser Gly 
        195                 200                 205             


Lys His Cys Glu Gln Gly Arg Glu Asn Cys Thr Phe Ala Pro Cys Leu 
    210                 215                 220                 


Glu Gly Gly Thr Cys Ile Leu Ser Pro Lys Gly Ala Ser Cys Asn Cys 
225                 230                 235                 240 


Pro His Pro Tyr Thr Gly Asp Arg Cys Glu Met Glu Ala Arg Gly Cys 
                245                 250                 255     


Ser Glu Gly His Cys Leu Val Thr Pro Glu Ile Gln Arg Gly Asp Trp 
            260                 265                 270         


Gly Gln Gln Glu 
        275     


<210>  433
<211>  654
<212>  PRT
<213>  Homo Sapiens

<400>  433

Asp Val Leu Leu Glu Ala Cys Cys Ala Asp Gly His Arg Met Ala Thr 
1               5                   10                  15      


His Gln Lys Asp Cys Ser Leu Pro Tyr Ala Thr Glu Ser Lys Glu Cys 
            20                  25                  30          


Arg Met Val Gln Glu Gln Cys Cys His Ser Gln Leu Glu Glu Leu His 
        35                  40                  45              


Cys Ala Thr Gly Ile Ser Leu Ala Asn Glu Gln Asp Arg Cys Ala Thr 
    50                  55                  60                  


Pro His Gly Asp Asn Ala Ser Leu Glu Ala Thr Phe Val Lys Arg Cys 
65                  70                  75                  80  


Cys His Cys Cys Leu Leu Gly Arg Ala Ala Gln Ala Gln Gly Gln Ser 
                85                  90                  95      


Cys Glu Tyr Ser Leu Met Val Gly Tyr Gln Cys Gly Gln Val Phe Arg 
            100                 105                 110         


Ala Cys Cys Val Lys Ser Gln Glu Thr Gly Asp Leu Asp Val Gly Gly 
        115                 120                 125             


Leu Gln Glu Thr Asp Lys Ile Ile Glu Val Glu Glu Glu Gln Glu Asp 
    130                 135                 140                 


Pro Tyr Leu Asn Asp Arg Cys Arg Gly Gly Gly Pro Cys Lys Gln Gln 
145                 150                 155                 160 


Cys Arg Asp Thr Gly Asp Glu Val Val Cys Ser Cys Phe Val Gly Tyr 
                165                 170                 175     


Gln Leu Leu Ser Asp Gly Val Ser Cys Glu Asp Val Asn Glu Cys Ile 
            180                 185                 190         


Thr Gly Ser His Ser Cys Arg Leu Gly Glu Ser Cys Ile Asn Thr Val 
        195                 200                 205             


Gly Ser Phe Arg Cys Gln Arg Asp Ser Ser Cys Gly Thr Gly Tyr Glu 
    210                 215                 220                 


Leu Thr Glu Asp Asn Ser Cys Lys Asp Ile Asp Glu Cys Glu Ser Gly 
225                 230                 235                 240 


Ile His Asn Cys Leu Pro Asp Phe Ile Cys Gln Asn Thr Leu Gly Ser 
                245                 250                 255     


Phe Arg Cys Arg Pro Lys Leu Gln Cys Lys Ser Gly Phe Ile Gln Asp 
            260                 265                 270         


Ala Leu Gly Asn Cys Ile Asp Ile Asn Glu Cys Leu Ser Ile Ser Ala 
        275                 280                 285             


Pro Cys Pro Ile Gly His Thr Cys Ile Asn Thr Glu Gly Ser Tyr Thr 
    290                 295                 300                 


Cys Gln Lys Asn Val Pro Asn Cys Gly Arg Gly Tyr His Leu Asn Glu 
305                 310                 315                 320 


Glu Gly Thr Arg Cys Val Asp Val Asp Glu Cys Ala Pro Pro Ala Glu 
                325                 330                 335     


Pro Cys Gly Lys Gly His Arg Cys Val Asn Ser Pro Gly Ser Phe Arg 
            340                 345                 350         


Cys Glu Cys Lys Thr Gly Tyr Tyr Phe Asp Gly Ile Ser Arg Met Cys 
        355                 360                 365             


Val Asp Val Asn Glu Cys Gln Arg Tyr Pro Gly Arg Leu Cys Gly His 
    370                 375                 380                 


Lys Cys Glu Asn Thr Leu Gly Ser Tyr Leu Cys Ser Cys Ser Val Gly 
385                 390                 395                 400 


Phe Arg Leu Ser Val Asp Gly Arg Ser Cys Glu Asp Ile Asn Glu Cys 
                405                 410                 415     


Ser Ser Ser Pro Cys Ser Gln Glu Cys Ala Asn Val Tyr Gly Ser Tyr 
            420                 425                 430         


Gln Cys Tyr Cys Arg Arg Gly Tyr Gln Leu Ser Asp Val Asp Gly Val 
        435                 440                 445             


Thr Cys Glu Asp Ile Asp Glu Cys Ala Leu Pro Thr Gly Gly His Ile 
    450                 455                 460                 


Cys Ser Tyr Arg Cys Ile Asn Ile Pro Gly Ser Phe Gln Cys Ser Cys 
465                 470                 475                 480 


Pro Ser Ser Gly Tyr Arg Leu Ala Pro Asn Gly Ser Asn Cys Gln Asp 
                485                 490                 495     


Ile Asp Glu Cys Val Thr Gly Ile His Asn Cys Ser Ile Asn Glu Thr 
            500                 505                 510         


Cys Phe Asn Ile Gln Gly Gly Phe Arg Cys Leu Ala Phe Glu Cys Pro 
        515                 520                 525             


Glu Asn Tyr Arg Arg Ser Ala Ala Thr Arg Cys Glu Arg Leu Pro Cys 
    530                 535                 540                 


His Glu Asn Arg Glu Cys Ser Lys Leu Pro Leu Arg Ile Thr Tyr Tyr 
545                 550                 555                 560 


His Leu Ser Phe Pro Thr Asn Ile Gln Ala Pro Ala Val Val Phe Arg 
                565                 570                 575     


Met Gly Pro Ser Ser Ala Val Pro Gly Asp Ser Met Gln Leu Ala Ile 
            580                 585                 590         


Thr Gly Gly Asn Glu Glu Gly Phe Phe Thr Thr Arg Lys Val Ser Pro 
        595                 600                 605             


His Ser Gly Val Val Ala Leu Thr Lys Pro Val Pro Glu Pro Arg Asp 
    610                 615                 620                 


Leu Leu Leu Thr Val Lys Met Asp Leu Ser Arg His Gly Thr Val Ser 
625                 630                 635                 640 


Ser Phe Val Ala Lys Leu Phe Ile Phe Val Ser Ala Glu Leu 
                645                 650                 


<210>  434
<211>  1157
<212>  PRT
<213>  Homo Sapiens

<400>  434

Ala Pro Arg Gln Asp Cys Thr Gly Val Glu Cys Pro Pro Leu Glu Asn 
1               5                   10                  15      


Cys Ile Glu Glu Ala Leu Glu Pro Gly Ala Cys Cys Ala Thr Cys Val 
            20                  25                  30          


Gln Gln Gly Cys Ala Cys Glu Gly Tyr Gln Tyr Tyr Asp Cys Leu Gln 
        35                  40                  45              


Gly Gly Phe Val Arg Gly Arg Val Pro Ala Gly Gln Ser Tyr Phe Val 
    50                  55                  60                  


Asp Phe Gly Ser Thr Glu Cys Ser Cys Pro Pro Gly Gly Gly Lys Ile 
65                  70                  75                  80  


Ser Cys Gln Phe Met Leu Cys Pro Glu Leu Pro Pro Asn Cys Ile Glu 
                85                  90                  95      


Ala Val Val Val Ala Asp Ser Cys Pro Gln Cys Gly Gln Val Gly Cys 
            100                 105                 110         


Val His Ala Gly His Lys Tyr Ala Ala Gly His Thr Val His Leu Pro 
        115                 120                 125             


Pro Cys Arg Ala Cys His Cys Pro Asp Ala Gly Gly Glu Leu Ile Cys 
    130                 135                 140                 


Tyr Gln Leu Pro Gly Cys His Gly Asn Phe Ser Asp Ala Glu Glu Gly 
145                 150                 155                 160 


Asp Pro Glu Arg His Tyr Glu Asp Pro Tyr Ser Tyr Asp Gln Glu Val 
                165                 170                 175     


Ala Glu Val Glu Ala Ala Thr Ala Leu Gly Gly Glu Val Gln Ala Gly 
            180                 185                 190         


Ala Val Gln Ala Gly Ala Gly Gly Pro Pro Ala Ala Leu Gly Gly Gly 
        195                 200                 205             


Ser Gln Pro Leu Ser Thr Ile Gln Ala Pro Pro Trp Pro Ala Val Leu 
    210                 215                 220                 


Pro Arg Pro Thr Ala Ala Ala Ala Leu Gly Pro Pro Ala Pro Val Gln 
225                 230                 235                 240 


Ala Lys Ala Arg Arg Val Thr Glu Asp Ser Glu Glu Glu Glu Glu Glu 
                245                 250                 255     


Glu Glu Glu Arg Glu Glu Met Ala Val Thr Glu Gln Leu Ala Ala Gly 
            260                 265                 270         


Gly His Arg Gly Leu Asp Gly Leu Pro Thr Thr Ala Pro Ala Gly Pro 
        275                 280                 285             


Ser Leu Pro Ile Gln Glu Glu Arg Ala Glu Ala Gly Ala Arg Ala Glu 
    290                 295                 300                 


Ala Gly Ala Arg Pro Glu Glu Asn Leu Ile Leu Asp Ala Gln Ala Thr 
305                 310                 315                 320 


Ser Arg Ser Thr Gly Pro Glu Gly Val Thr His Ala Pro Ser Leu Gly 
                325                 330                 335     


Lys Ala Ala Leu Val Pro Thr Gln Ala Val Pro Gly Ser Pro Arg Asp 
            340                 345                 350         


Pro Val Lys Pro Ser Pro His Asn Ile Leu Ser Thr Ser Leu Pro Asp 
        355                 360                 365             


Ala Ala Trp Ile Pro Pro Thr Arg Glu Val Pro Arg Lys Pro Gln Val 
    370                 375                 380                 


Leu Pro His Ser His Val Glu Glu Asp Thr Asp Pro Asn Ser Val His 
385                 390                 395                 400 


Ser Ile Pro Arg Ser Ser Pro Glu Gly Ser Thr Lys Asp Leu Ile Glu 
                405                 410                 415     


Thr Cys Cys Ala Ala Gly Gln Gln Trp Ala Ile Asp Asn Asp Glu Cys 
            420                 425                 430         


Leu Glu Ile Pro Glu Ser Gly Thr Glu Asp Asn Val Cys Arg Thr Ala 
        435                 440                 445             


Gln Arg His Cys Cys Val Ser Tyr Leu Gln Glu Lys Ser Cys Met Ala 
    450                 455                 460                 


Gly Val Leu Gly Ala Lys Glu Gly Glu Thr Cys Gly Ala Glu Asp Asn 
465                 470                 475                 480 


Asp Ser Cys Gly Ile Ser Leu Tyr Lys Gln Cys Cys Asp Cys Cys Gly 
                485                 490                 495     


Leu Gly Leu Arg Val Arg Ala Glu Gly Gln Ser Cys Glu Ser Asn Pro 
            500                 505                 510         


Asn Leu Gly Tyr Pro Cys Asn His Val Met Leu Ser Cys Cys Glu Gly 
        515                 520                 525             


Glu Glu Pro Leu Ile Val Pro Glu Val Arg Arg Pro Pro Glu Pro Ala 
    530                 535                 540                 


Ala Ala Pro Arg Arg Val Ser Glu Ala Glu Met Ala Gly Arg Glu Ala 
545                 550                 555                 560 


Leu Ser Leu Gly Thr Glu Ala Glu Leu Pro Asn Ser Leu Pro Gly Asp 
                565                 570                 575     


Asp Gln Asp Glu Cys Leu Leu Leu Pro Gly Glu Leu Cys Gln His Leu 
            580                 585                 590         


Cys Ile Asn Thr Val Gly Ser Tyr His Cys Ala Cys Phe Pro Gly Phe 
        595                 600                 605             


Ser Leu Gln Asp Asp Gly Arg Thr Cys Arg Pro Glu Gly His Pro Pro 
    610                 615                 620                 


Gln Pro Glu Ala Pro Gln Glu Pro Ala Leu Lys Ser Glu Phe Ser Gln 
625                 630                 635                 640 


Val Ala Ser Asn Thr Ile Pro Leu Pro Leu Pro Gln Pro Asn Thr Cys 
                645                 650                 655     


Lys Asp Asn Gly Pro Cys Lys Gln Val Cys Ser Thr Val Gly Gly Ser 
            660                 665                 670         


Ala Ile Cys Ser Cys Phe Pro Gly Tyr Ala Ile Met Ala Asp Gly Val 
        675                 680                 685             


Ser Cys Glu Asp Ile Asn Glu Cys Val Thr Asp Leu His Thr Cys Ser 
    690                 695                 700                 


Arg Gly Glu His Cys Val Asn Thr Leu Gly Ser Phe His Cys Tyr Lys 
705                 710                 715                 720 


Ala Leu Thr Cys Glu Pro Gly Tyr Ala Leu Lys Asp Gly Glu Cys Glu 
                725                 730                 735     


Asp Val Asp Glu Cys Ala Met Gly Thr His Thr Cys Gln Pro Gly Phe 
            740                 745                 750         


Leu Cys Gln Asn Thr Lys Gly Ser Phe Tyr Cys Gln Ala Arg Gln Arg 
        755                 760                 765             


Cys Met Asp Gly Phe Leu Gln Asp Pro Glu Gly Asn Cys Val Asp Ile 
    770                 775                 780                 


Asn Glu Cys Thr Ser Leu Ser Glu Pro Cys Arg Pro Gly Phe Ser Cys 
785                 790                 795                 800 


Ile Asn Thr Val Gly Ser Tyr Thr Cys Gln Arg Asn Pro Leu Ile Cys 
                805                 810                 815     


Ala Arg Gly Tyr His Ala Ser Asp Asp Gly Ala Lys Cys Val Asp Val 
            820                 825                 830         


Asn Glu Cys Glu Thr Gly Val His Arg Cys Gly Glu Gly Gln Val Cys 
        835                 840                 845             


His Asn Leu Pro Gly Ser Tyr Arg Cys Asp Cys Lys Ala Gly Phe Gln 
    850                 855                 860                 


Arg Asp Ala Phe Gly Arg Gly Cys Ile Asp Val Asn Glu Cys Trp Ala 
865                 870                 875                 880 


Ser Pro Gly Arg Leu Cys Gln His Thr Cys Glu Asn Thr Leu Gly Ser 
                885                 890                 895     


Tyr Arg Cys Ser Cys Ala Ser Gly Phe Leu Leu Ala Ala Asp Gly Lys 
            900                 905                 910         


Arg Cys Glu Asp Val Asn Glu Cys Glu Ala Gln Arg Cys Ser Gln Glu 
        915                 920                 925             


Cys Ala Asn Ile Tyr Gly Ser Tyr Gln Cys Tyr Cys Arg Gln Gly Tyr 
    930                 935                 940                 


Gln Leu Ala Glu Asp Gly His Thr Cys Thr Asp Ile Asp Glu Cys Ala 
945                 950                 955                 960 


Gln Gly Ala Gly Ile Leu Cys Thr Phe Arg Cys Leu Asn Val Pro Gly 
                965                 970                 975     


Ser Tyr Gln Cys Ala Cys Pro Glu Gln Gly Tyr Thr Met Thr Ala Asn 
            980                 985                 990         


Gly Arg Ser Cys Lys Asp Val Asp  Glu Cys Ala Leu Gly  Thr His Asn 
        995                 1000                 1005             


Cys Ser  Glu Ala Glu Thr Cys  His Asn Ile Gln Gly  Ser Phe Arg 
    1010                 1015                 1020             


Cys Leu  Arg Leu Glu Cys Pro  Pro Asn Tyr Val Gln  Val Ser Lys 
    1025                 1030                 1035             


Thr Lys  Cys Glu Arg Thr Thr  Cys His Asp Phe Leu  Glu Cys Gln 
    1040                 1045                 1050             


Asn Ser  Pro Ala Arg Ile Thr  His Tyr Gln Leu Asn  Phe Gln Thr 
    1055                 1060                 1065             


Gly Leu  Leu Val Pro Ala His  Ile Phe Arg Ile Gly  Pro Ala Pro 
    1070                 1075                 1080             


Ala Phe  Thr Gly Asp Thr Ile  Ala Leu Asn Ile Ile  Lys Gly Asn 
    1085                 1090                 1095             


Glu Glu  Gly Tyr Phe Gly Thr  Arg Arg Leu Asn Ala  Tyr Thr Gly 
    1100                 1105                 1110             


Val Val  Tyr Leu Gln Arg Ala  Val Leu Glu Pro Arg  Asp Phe Ala 
    1115                 1120                 1125             


Leu Asp  Val Glu Met Lys Leu  Trp Arg Gln Gly Ser  Val Thr Thr 
    1130                 1135                 1140             


Phe Leu  Ala Lys Met His Ile  Phe Phe Thr Thr Phe  Ala Leu 
    1145                 1150                 1155         


<210>  435
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  435

Gln Ala Gln Cys Thr Asn Gly Phe Asp Leu Asp Arg Gln Ser Gly Gln 
1               5                   10                  15      


Cys Leu Asp Ile Asp Glu Cys Arg Thr Ile Pro Glu Ala Cys Arg Gly 
            20                  25                  30          


Asp Met Met Cys Val Asn Gln Asn Gly Gly Tyr Leu Cys Ile Pro Arg 
        35                  40                  45              


Thr Asn Pro Val Tyr Arg Gly Pro Tyr Ser Asn Pro Tyr Ser Thr Pro 
    50                  55                  60                  


Tyr Ser Gly Pro Tyr Pro Ala Ala Ala Pro Pro Leu Ser Ala Pro Asn 
65                  70                  75                  80  


Tyr Pro Thr Ile Ser Arg Pro Leu Ile Cys Arg Phe Gly Tyr Gln Met 
                85                  90                  95      


Asp Glu Ser Asn Gln Cys Val Asp Val Asp Glu Cys Ala Thr Asp Ser 
            100                 105                 110         


His Gln Cys Asn Pro Thr Gln Ile Cys Ile Asn Thr Glu Gly Gly Tyr 
        115                 120                 125             


Thr Cys Ser Cys Thr Asp Gly Tyr Trp Leu Leu Glu Gly Gln Cys Leu 
    130                 135                 140                 


Asp Ile Asp Glu Cys Arg Tyr Gly Tyr Cys Gln Gln Leu Cys Ala Asn 
145                 150                 155                 160 


Val Pro Gly Ser Tyr Ser Cys Thr Cys Asn Pro Gly Phe Thr Leu Asn 
                165                 170                 175     


Glu Asp Gly Arg Ser Cys Gln Asp Val Asn Glu Cys Ala Thr Glu Asn 
            180                 185                 190         


Pro Cys Val Gln Thr Cys Val Asn Thr Tyr Gly Ser Phe Ile Cys Arg 
        195                 200                 205             


Cys Asp Pro Gly Tyr Glu Leu Glu Glu Asp Gly Val His Cys Ser Asp 
    210                 215                 220                 


Met Asp Glu Cys Ser Phe Ser Glu Phe Leu Cys Gln His Glu Cys Val 
225                 230                 235                 240 


Asn Gln Pro Gly Thr Tyr Phe Cys Ser Cys Pro Pro Gly Tyr Ile Leu 
                245                 250                 255     


Leu Asp Asp Asn Arg Ser Cys Gln Asp Ile Asn Glu Cys Glu His Arg 
            260                 265                 270         


Asn His Thr Cys Asn Leu Gln Gln Thr Cys Tyr Asn Leu Gln Gly Gly 
        275                 280                 285             


Phe Lys Cys Ile Asp Pro Ile Arg Cys Glu Glu Pro Tyr Leu Arg Ile 
    290                 295                 300                 


Ser Asp Asn Arg Cys Met Cys Pro Ala Glu Asn Pro Gly Cys Arg Asp 
305                 310                 315                 320 


Gln Pro Phe Thr Ile Leu Tyr Arg Asp Met Asp Val Val Ser Gly Arg 
                325                 330                 335     


Ser Val Pro Ala Asp Ile Phe Gln Met Gln Ala Thr Thr Arg Tyr Pro 
            340                 345                 350         


Gly Ala Tyr Tyr Ile Phe Gln Ile Lys Ser Gly Asn Glu Gly Arg Glu 
        355                 360                 365             


Phe Tyr Met Arg Gln Thr Gly Pro Ile Ser Ala Thr Leu Val Met Thr 
    370                 375                 380                 


Arg Pro Ile Lys Gly Pro Arg Glu Ile Gln Leu Asp Leu Glu Met Ile 
385                 390                 395                 400 


Thr Val Asn Thr Val Ile Asn Phe Arg Gly Ser Ser Val Ile Arg Leu 
                405                 410                 415     


Arg Ile Tyr Val Ser Gln Tyr Pro Phe 
            420                 425 


<210>  436
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  436

Gln Asn Cys Leu Ser Lys Gln Gln Leu Leu Ser Ala Ile Arg Gln Leu 
1               5                   10                  15      


Gln Gln Leu Leu Lys Gly Gln Glu Thr Arg Phe Ala Glu Gly Ile Arg 
            20                  25                  30          


His Met Lys Ser Arg Leu Ala Ala Leu Gln Asn Ser Val Gly Arg Val 
        35                  40                  45              


Gly Pro Asp Ala Leu Pro Val Ser Cys Pro Ala Leu Asn Thr Pro Ala 
    50                  55                  60                  


Asp Gly Arg Lys Phe Gly Ser Lys Tyr Leu Val Asp His Glu Val His 
65                  70                  75                  80  


Phe Thr Cys Asn Pro Gly Phe Arg Leu Val Gly Pro Ser Ser Val Val 
                85                  90                  95      


Cys Leu Pro Asn Gly Thr Trp Thr Gly Glu Gln Pro His Cys Arg Gly 
            100                 105                 110         


Ile Ser Glu Cys Ser Ser Gln Pro Cys Gln Asn Gly Gly Thr Cys Val 
        115                 120                 125             


Glu Gly Val Asn Gln Tyr Arg Cys Ile Cys Pro Pro Gly Arg Thr Gly 
    130                 135                 140                 


Asn Arg Cys Gln His Gln Ala Gln Thr Ala Ala Pro Glu Gly Ser Val 
145                 150                 155                 160 


Ala Gly Asp Ser Ala Phe Ser Arg Ala Pro Arg Cys Ala Gln Val Glu 
                165                 170                 175     


Arg Ala Gln His Cys Ser Cys Glu Ala Gly Phe His Leu Ser Gly Ala 
            180                 185                 190         


Ala Gly Asp Ser Val Cys Gln Asp Val Asn Glu Cys Glu Leu Tyr Gly 
        195                 200                 205             


Gln Glu Gly Arg Pro Arg Leu Cys Met His Ala Cys Val Asn Thr Pro 
    210                 215                 220                 


Gly Ser Tyr Arg Cys Thr Cys Pro Gly Gly Tyr Arg Thr Leu Ala Asp 
225                 230                 235                 240 


Gly Lys Ser Cys Glu Asp Val Asp Glu Cys Val Gly Leu Gln Pro Val 
                245                 250                 255     


Cys Pro Gln Gly Thr Thr Cys Ile Asn Thr Gly Gly Ser Phe Gln Cys 
            260                 265                 270         


Val Ser Pro Glu Cys Pro Glu Gly Ser Gly Asn Val Ser Tyr Val Lys 
        275                 280                 285             


Thr Ser Pro Phe Gln Cys Glu Arg Asn Pro Cys Pro Met Asp Ser Arg 
    290                 295                 300                 


Pro Cys Arg His Leu Pro Lys Thr Ile Ser Phe His Tyr Leu Ser Leu 
305                 310                 315                 320 


Pro Ser Asn Leu Lys Thr Pro Ile Thr Leu Phe Arg Met Ala Thr Ala 
                325                 330                 335     


Ser Ala Pro Gly Arg Ala Gly Pro Asn Ser Leu Arg Phe Gly Ile Val 
            340                 345                 350         


Gly Gly Asn Ser Arg Gly His Phe Val Met Gln Arg Ser Asp Arg Gln 
        355                 360                 365             


Thr Gly Asp Leu Ile Leu Val Gln Asn Leu Glu Gly Pro Gln Thr Leu 
    370                 375                 380                 


Glu Val Asp Val Asp Met Ser Glu Tyr Leu Asp Arg Ser Phe Gln Ala 
385                 390                 395                 400 


Asn His Val Ser Lys Val Thr Ile Phe Val Ser Pro Tyr Asp Phe 
                405                 410                 415 


<210>  437
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  437

Gly Gln Gln Asp Val Leu Arg Gly Pro Asn Val Cys Gly Ser Arg Phe 
1               5                   10                  15      


His Ser Tyr Cys Cys Pro Gly Trp Lys Thr Leu Pro Gly Gly Asn Gln 
            20                  25                  30          


Cys Ile Val Pro Ile Cys Arg Asn Ser Cys Gly Asp Gly Phe Cys Ser 
        35                  40                  45              


Arg Pro Asn Met Cys Thr Cys Ser Ser Gly Gln Ile Ser Ser Thr Cys 
    50                  55                  60                  


Gly Ser Lys Ser Ile Gln Gln Cys Ser Val Arg Cys Met Asn Gly Gly 
65                  70                  75                  80  


Thr Cys Ala Asp Asp His Cys Gln Cys Gln Lys Gly Tyr Ile Gly Thr 
                85                  90                  95      


Tyr Cys Gly Gln Pro Val Cys Glu Asn Gly Cys Gln Asn Gly Gly Arg 
            100                 105                 110         


Cys Ile Gly Pro Asn Arg Cys Ala Cys Val Tyr Gly Phe Thr Gly Pro 
        115                 120                 125             


Gln Cys Glu Arg Asp Tyr Arg Thr Gly Pro Cys Phe Thr Gln Val Asn 
    130                 135                 140                 


Asn Gln Met Cys Gln Gly Gln Leu Thr Gly Ile Val Cys Thr Lys Thr 
145                 150                 155                 160 


Leu Cys Cys Ala Thr Ile Gly Arg Ala Trp Gly His Pro Cys Glu Met 
                165                 170                 175     


Cys Pro Ala Gln Pro Gln Pro Cys Arg Arg Gly Phe Ile Pro Asn Ile 
            180                 185                 190         


Arg Thr Gly Ala Cys Gln Asp Val Asp Glu Cys Gln Ala Ile Pro Gly 
        195                 200                 205             


Ile Cys Gln Gly Gly Asn Cys Ile Asn Thr Val Gly Ser Phe Glu Cys 
    210                 215                 220                 


Arg Cys Pro Ala Gly His Lys Gln Ser Glu Thr Thr Gln Lys Cys Glu 
225                 230                 235                 240 


Asp Ile Asp Glu Cys Ser Ile Ile Pro Gly Ile Cys Glu Thr Gly Glu 
                245                 250                 255     


Cys Ser Asn Thr Val Gly Ser Tyr Phe Cys Val Cys Pro Arg Gly Tyr 
            260                 265                 270         


Val Thr Ser Thr Asp Gly Ser Arg Cys Ile 
        275                 280         


<210>  438
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  438

Ser Ala His Arg Asp His Gln Val Asn Leu Ala Thr Leu Asp Ser Glu 
1               5                   10                  15      


Ala Leu Leu Thr Leu Gly Leu Asn Leu Ser His Leu Gly Arg Ala Glu 
            20                  25                  30          


Arg Ile Leu Glu Leu Arg Pro Ala Leu Glu Gly Leu Glu Gly Arg Ile 
        35                  40                  45              


Arg Tyr Val Ile Val Arg Gly Asn Glu Gln Gly Phe Phe Arg Met His 
    50                  55                  60                  


His Leu Arg Gly Val Ser Ser Leu Gln Leu Gly Arg Arg Arg Pro Gly 
65                  70                  75                  80  


Pro Gly Thr Tyr Arg Leu Glu Val Val Ser His Met Ala Gly Pro Trp 
                85                  90                  95      


Gly Val Gln Pro Glu Gly Gln Pro Gly Pro Trp Gly Gln Ala Leu Arg 
            100                 105                 110         


Leu Lys Val Gln Leu Gln Leu Leu 
        115                 120 


<210>  439
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  439

Leu Pro Gln Lys Arg Pro His Pro Arg Trp Leu Trp Glu Gly Ser Leu 
1               5                   10                  15      


Pro Ser Arg Thr His Leu Arg Ala Met Gly Thr Leu Arg Pro Ser Ser 
            20                  25                  30          


Pro Leu Cys Trp Arg Glu Glu Ser Ser Phe Ala Ala Pro Asn Ser Leu 
        35                  40                  45              


Lys Gly Ser Arg Leu Val Ser Gly Glu Pro Gly Gly Ala Val Thr Ile 
    50                  55                  60                  


Gln Cys His Tyr Ala Pro Ser Ser Val Asn Arg His Gln Arg Lys Tyr 
65                  70                  75                  80  


Trp Cys Arg Leu Gly Pro Pro Arg Trp Ile Cys Gln Thr Ile Val Ser 
                85                  90                  95      


Thr Asn Gln Tyr Thr His His Arg Tyr Arg Asp Arg Val Ala Leu Thr 
            100                 105                 110         


Asp Phe Pro Gln Arg Gly Leu Phe Val Val Arg Leu Ser Gln Leu Ser 
        115                 120                 125             


Pro Asp Asp Ile Gly Cys Tyr Leu Cys Gly Ile Gly Ser Glu Asn Asn 
    130                 135                 140                 


Met Leu Phe Leu Ser Met Asn Leu Thr Ile Ser Ala Gly Pro Ala Ser 
145                 150                 155                 160 


Thr Leu Pro Thr Ala Thr Pro Ala Ala Gly Glu Leu Thr Met Arg Ser 
                165                 170                 175     


Tyr Gly Thr Ala Ser Pro Val Ala Asn Arg Trp Thr Pro Gly Thr Thr 
            180                 185                 190         


Gln Thr Leu Gly Gln Gly Thr Ala Trp Asp Thr Val Ala Ser Thr Pro 
        195                 200                 205             


Gly Thr Ser Lys Thr Thr Ala Ser Ala Glu Gly Arg Arg Thr Pro Gly 
    210                 215                 220                 


Ala Thr Arg Pro Ala Ala Pro Gly Thr Gly Ser Trp Ala Glu Gly Ser 
225                 230                 235                 240 


Val Lys Ala Pro Ala Pro Ile Pro Glu Ser Pro Pro Ser Lys Ser Arg 
                245                 250                 255     


Ser Met Ser Asn Thr Thr Glu Gly Val Trp Glu Gly Thr Arg Ser Ser 
            260                 265                 270         


Val Thr Asn Arg Ala Arg Ala Ser Lys Asp Arg Arg Glu Met Thr Thr 
        275                 280                 285             


Thr Lys Ala Asp Arg Pro Arg Glu Asp Ile Glu Gly Val Arg Ile Ala 
    290                 295                 300                 


Leu Asp Ala Ala Lys Lys Val Leu Gly Thr Ile Gly Pro Pro Ala Leu 
305                 310                 315                 320 


Val Ser Glu Thr Leu Ala Trp Glu Ile Leu Pro Gln Ala Thr Pro Val 
                325                 330                 335     


Ser Lys Gln Gln Ser Gln Gly Ser Ile Gly Glu Thr Thr Pro Ala Ala 
            340                 345                 350         


Gly Met Trp Thr Leu Gly Thr Pro Ala Ala Asp Val Trp Ile Leu Gly 
        355                 360                 365             


Thr Pro Ala Ala Asp Val Trp Thr Ser Met Glu Ala Ala Ser Gly Glu 
    370                 375                 380                 


Gly Ser Ala Ala Gly Asp Leu Asp Ala Ala Thr Gly Asp Arg Gly Pro 
385                 390                 395                 400 


Gln Ala Thr Leu Ser Gln Thr Pro Ala Val Gly Pro Trp Gly Pro Pro 
                405                 410                 415     


Gly Lys Glu Ser Ser Val Lys Arg Thr Phe Pro Glu Asp Glu Ser Ser 
            420                 425                 430         


Ser Arg 
        


<210>  440
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  440

Gln Glu Gly Asp Phe Pro Met Pro Phe Ile Ser Ala Lys Ser Ser Pro 
1               5                   10                  15      


Val Ile Pro Leu Asp Gly Ser Val Lys Ile Gln Cys Gln Ala Ile Arg 
            20                  25                  30          


Glu Ala Tyr Leu Thr Gln Leu Met Ile Ile Lys Asn Ser Thr Tyr Arg 
        35                  40                  45              


Glu Ile Gly Arg Arg Leu Lys Phe Trp Asn Glu Thr Asp Pro Glu Phe 
    50                  55                  60                  


Val Ile Asp His Met Asp Ala Asn Lys Ala Gly Arg Tyr Gln Cys Gln 
65                  70                  75                  80  


Tyr Arg Ile Gly His Tyr Arg Phe Arg Tyr Ser Asp Thr Leu Glu Leu 
                85                  90                  95      


Val Val Thr Gly Leu Tyr Gly Lys Pro Phe Leu Ser Ala Asp Arg Gly 
            100                 105                 110         


Leu Val Leu Met Pro Gly Glu Asn Ile Ser Leu Thr Cys Ser Ser Ala 
        115                 120                 125             


His Ile Pro Phe Asp Arg Phe Ser Leu Ala Lys Glu Gly Glu Leu Ser 
    130                 135                 140                 


Leu Pro Gln His Gln Ser Gly Glu His Pro Ala Asn Phe Ser Leu Gly 
145                 150                 155                 160 


Pro Val Asp Leu Asn Val Ser Gly Ile Tyr Arg Cys Tyr Gly Trp Tyr 
                165                 170                 175     


Asn Arg Ser Pro Tyr Leu Trp Ser Phe Pro Ser Asn Ala Leu Glu Leu 
            180                 185                 190         


Val Val Thr Asp Ser Ile His Gln Asp Tyr Thr Thr Gln Asn 
        195                 200                 205     


<210>  441
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  441

Val Pro Gln Lys Pro Lys Val Ser Leu Asn Pro Pro Trp Asn Arg Ile 
1               5                   10                  15      


Phe Lys Gly Glu Asn Val Thr Leu Thr Cys Asn Gly Asn Asn Phe Phe 
            20                  25                  30          


Glu Val Ser Ser Thr Lys Trp Phe His Asn Gly Ser Leu Ser Glu Glu 
        35                  40                  45              


Thr Asn Ser Ser Leu Asn Ile Val Asn Ala Lys Phe Glu Asp Ser Gly 
    50                  55                  60                  


Glu Tyr Lys Cys Gln His Gln Gln Val Asn Glu Ser Glu Pro Val Tyr 
65                  70                  75                  80  


Leu Glu Val Phe Ser Asp Trp Leu Leu Leu Gln Ala Ser Ala Glu Val 
                85                  90                  95      


Val Met Glu Gly Gln Pro Leu Phe Leu Arg Cys His Gly Trp Arg Asn 
            100                 105                 110         


Trp Asp Val Tyr Lys Val Ile Tyr Tyr Lys Asp Gly Glu Ala Leu Lys 
        115                 120                 125             


Tyr Trp Tyr Glu Asn His Asn Ile Ser Ile Thr Asn Ala Thr Val Glu 
    130                 135                 140                 


Asp Ser Gly Thr Tyr Tyr Cys Thr Gly Lys Val Trp Gln Leu Asp Tyr 
145                 150                 155                 160 


Glu Ser Glu Pro Leu Asn Ile Thr Val Ile Lys Ala Pro Arg Glu Lys 
                165                 170                 175     


Tyr Trp Leu Gln 
            180 


<210>  442
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  442

Met Glu Leu Gln Val Ser Ser Gly Phe Val Cys Asn Thr Cys Pro Glu 
1               5                   10                  15      


Lys Trp Ile Asn Phe Gln Arg Lys Cys Tyr Tyr Phe Gly Lys Gly Thr 
            20                  25                  30          


Lys Gln Trp Val His Ala Arg Tyr Ala Cys Asp Asp Met Glu Gly Gln 
        35                  40                  45              


Leu Val Ser Ile His Ser Pro Glu Glu Gln Asp Phe Leu Thr Lys His 
    50                  55                  60                  


Ala Ser His Thr Gly Ser Trp Ile Gly Leu Arg Asn Leu Asp Leu Lys 
65                  70                  75                  80  


Gly Glu Phe Ile Trp Val Asp Gly Ser His Val Asp Tyr Ser Asn Trp 
                85                  90                  95      


Ala Pro Gly Glu Pro Thr Ser Arg Ser Gln Gly Glu Asp Cys Val Met 
            100                 105                 110         


Met Arg Gly Ser Gly Arg Trp Asn Asp Ala Phe Cys Asp Arg Lys Leu 
        115                 120                 125             


Gly Ala Trp Val Cys Asp Arg Leu Ala Thr Cys Thr Pro Pro Ala Ser 
    130                 135                 140                 


Glu Gly Ser Ala Glu Ser Met Gly Pro Asp Ser Arg Pro Asp Pro Asp 
145                 150                 155                 160 


Gly Arg Leu Pro Thr Pro Ser Ala Pro Leu His Ser 
                165                 170         


<210>  443
<211>  277
<212>  PRT
<213>  Homo Sapiens

<400>  443

Gln Val Asp Thr Thr Lys Ala Val Ile Thr Leu Gln Pro Pro Trp Val 
1               5                   10                  15      


Ser Val Phe Gln Glu Glu Thr Val Thr Leu His Cys Glu Val Leu His 
            20                  25                  30          


Leu Pro Gly Ser Ser Ser Thr Gln Trp Phe Leu Asn Gly Thr Ala Thr 
        35                  40                  45              


Gln Thr Ser Thr Pro Ser Tyr Arg Ile Thr Ser Ala Ser Val Asn Asp 
    50                  55                  60                  


Ser Gly Glu Tyr Arg Cys Gln Arg Gly Leu Ser Gly Arg Ser Asp Pro 
65                  70                  75                  80  


Ile Gln Leu Glu Ile His Arg Gly Trp Leu Leu Leu Gln Val Ser Ser 
                85                  90                  95      


Arg Val Phe Thr Glu Gly Glu Pro Leu Ala Leu Arg Cys His Ala Trp 
            100                 105                 110         


Lys Asp Lys Leu Val Tyr Asn Val Leu Tyr Tyr Arg Asn Gly Lys Ala 
        115                 120                 125             


Phe Lys Phe Phe His Trp Asn Ser Asn Leu Thr Ile Leu Lys Thr Asn 
    130                 135                 140                 


Ile Ser His Asn Gly Thr Tyr His Cys Ser Gly Met Gly Lys His Arg 
145                 150                 155                 160 


Tyr Thr Ser Ala Gly Ile Ser Val Thr Val Lys Glu Leu Phe Pro Ala 
                165                 170                 175     


Pro Val Leu Asn Ala Ser Val Thr Ser Pro Leu Leu Glu Gly Asn Leu 
            180                 185                 190         


Val Thr Leu Ser Cys Glu Thr Lys Leu Leu Leu Gln Arg Pro Gly Leu 
        195                 200                 205             


Gln Leu Tyr Phe Ser Phe Tyr Met Gly Ser Lys Thr Leu Arg Gly Arg 
    210                 215                 220                 


Asn Thr Ser Ser Glu Tyr Gln Ile Leu Thr Ala Arg Arg Glu Asp Ser 
225                 230                 235                 240 


Gly Leu Tyr Trp Cys Glu Ala Ala Thr Glu Asp Gly Asn Val Leu Lys 
                245                 250                 255     


Arg Ser Pro Glu Leu Glu Leu Gln Val Leu Gly Leu Gln Leu Pro Thr 
            260                 265                 270         


Pro Val Trp Phe His 
        275         


<210>  444
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  444

Gln Val Asp Thr Thr Lys Ala Val Ile Thr Leu Gln Pro Pro Trp Val 
1               5                   10                  15      


Ser Val Phe Gln Glu Glu Thr Val Thr Leu His Cys Glu Val Leu His 
            20                  25                  30          


Leu Pro Gly Ser Ser Ser Thr Gln Trp Phe Leu Asn Gly Thr Ala Thr 
        35                  40                  45              


Gln Thr Ser Thr Pro Ser Tyr Arg Ile Thr Ser Ala Ser Val Asn Asp 
    50                  55                  60                  


Ser Gly Glu Tyr Arg Cys Gln Arg Gly Leu Ser Gly Arg Ser Asp Pro 
65                  70                  75                  80  


Ile Gln Leu Glu Ile His Arg Gly Trp Leu Leu Leu Gln Val Ser Ser 
                85                  90                  95      


Arg Val Phe Met Glu Gly Glu Pro Leu Ala Leu Arg Cys His Ala Trp 
            100                 105                 110         


Lys Asp Lys Leu Val Tyr Asn Val Leu Tyr Tyr Arg Asn Gly Lys Ala 
        115                 120                 125             


Phe Lys Phe Phe His Trp Asn Ser Asn Leu Thr Ile Leu Lys Thr Asn 
    130                 135                 140                 


Ile Ser His Asn Gly Thr Tyr His Cys Ser Gly Met Gly Lys His Arg 
145                 150                 155                 160 


Tyr Thr Ser Ala Gly Ile Ser Gln Tyr Thr Val Lys Gly Leu Gln Leu 
                165                 170                 175     


Pro Thr Pro Val Trp Phe His 
            180             


<210>  445
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  445

Gln Ala Ala Pro Pro Lys Ala Val Leu Lys Leu Glu Pro Pro Trp Ile 
1               5                   10                  15      


Asn Val Leu Gln Glu Asp Ser Val Thr Leu Thr Cys Gln Gly Ala Arg 
            20                  25                  30          


Ser Pro Glu Ser Asp Ser Ile Gln Trp Phe His Asn Gly Asn Leu Ile 
        35                  40                  45              


Pro Thr His Thr Gln Pro Ser Tyr Arg Phe Lys Ala Asn Asn Asn Asp 
    50                  55                  60                  


Ser Gly Glu Tyr Thr Cys Gln Thr Gly Gln Thr Ser Leu Ser Asp Pro 
65                  70                  75                  80  


Val His Leu Thr Val Leu Ser Glu Trp Leu Val Leu Gln Thr Pro His 
                85                  90                  95      


Leu Glu Phe Gln Glu Gly Glu Thr Ile Met Leu Arg Cys His Ser Trp 
            100                 105                 110         


Lys Asp Lys Pro Leu Val Lys Val Thr Phe Phe Gln Asn Gly Lys Ser 
        115                 120                 125             


Gln Lys Phe Ser His Leu Asp Pro Thr Phe Ser Ile Pro Gln Ala Asn 
    130                 135                 140                 


His Ser His Ser Gly Asp Tyr His Cys Thr Gly Asn Ile Gly Tyr Thr 
145                 150                 155                 160 


Leu Phe Ser Ser Lys Pro Val Thr Ile Thr Val Gln Val Pro Ser Met 
                165                 170                 175     


Gly Ser Ser Ser Pro Met Gly 
            180             


<210>  446
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  446

Thr Pro Ala Ala Pro Pro Lys Ala Val Leu Lys Leu Glu Pro Gln Trp 
1               5                   10                  15      


Ile Asn Val Leu Gln Glu Asp Ser Val Thr Leu Thr Cys Arg Gly Thr 
            20                  25                  30          


His Ser Pro Glu Ser Asp Ser Ile Gln Trp Phe His Asn Gly Asn Leu 
        35                  40                  45              


Ile Pro Thr His Thr Gln Pro Ser Tyr Arg Phe Lys Ala Asn Asn Asn 
    50                  55                  60                  


Asp Ser Gly Glu Tyr Thr Cys Gln Thr Gly Gln Thr Ser Leu Ser Asp 
65                  70                  75                  80  


Pro Val His Leu Thr Val Leu Ser Glu Trp Leu Val Leu Gln Thr Pro 
                85                  90                  95      


His Leu Glu Phe Gln Glu Gly Glu Thr Ile Val Leu Arg Cys His Ser 
            100                 105                 110         


Trp Lys Asp Lys Pro Leu Val Lys Val Thr Phe Phe Gln Asn Gly Lys 
        115                 120                 125             


Ser Lys Lys Phe Ser Arg Ser Asp Pro Asn Phe Ser Ile Pro Gln Ala 
    130                 135                 140                 


Asn His Ser His Ser Gly Asp Tyr His Cys Thr Gly Asn Ile Gly Tyr 
145                 150                 155                 160 


Thr Leu Tyr Ser Ser Lys Pro Val Thr Ile Thr Val Gln Ala Pro 
                165                 170                 175 


<210>  447
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  447

Thr Pro Ala Ala Pro Pro Lys Ala Val Leu Lys Leu Glu Pro Gln Trp 
1               5                   10                  15      


Ile Asn Val Leu Gln Glu Asp Ser Val Thr Leu Thr Cys Arg Gly Thr 
            20                  25                  30          


His Ser Pro Glu Ser Asp Ser Ile Gln Trp Phe His Asn Gly Asn Leu 
        35                  40                  45              


Ile Pro Thr His Thr Gln Pro Ser Tyr Arg Phe Lys Ala Asn Asn Asn 
    50                  55                  60                  


Asp Ser Gly Glu Tyr Thr Cys Gln Thr Gly Gln Thr Ser Leu Ser Asp 
65                  70                  75                  80  


Pro Val His Leu Thr Val Leu Ser Glu Trp Leu Val Leu Gln Thr Pro 
                85                  90                  95      


His Leu Glu Phe Gln Glu Gly Glu Thr Ile Val Leu Arg Cys His Ser 
            100                 105                 110         


Trp Lys Asp Lys Pro Leu Val Lys Val Thr Phe Phe Gln Asn Gly Lys 
        115                 120                 125             


Ser Lys Lys Phe Ser Arg Ser Asp Pro Asn Phe Ser Ile Pro Gln Ala 
    130                 135                 140                 


Asn His Ser His Ser Gly Asp Tyr His Cys Thr Gly Asn Ile Gly Tyr 
145                 150                 155                 160 


Thr Leu Tyr Ser Ser Lys Pro Val Thr Ile Thr Val Gln Ala Pro 
                165                 170                 175 


<210>  448
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  448

Thr Pro Ala Ala Pro Pro Lys Ala Val Leu Lys Leu Glu Pro Gln Trp 
1               5                   10                  15      


Ile Asn Val Leu Gln Glu Asp Ser Val Thr Leu Thr Cys Arg Gly Thr 
            20                  25                  30          


His Ser Pro Glu Ser Asp Ser Ile Gln Trp Phe His Asn Gly Asn Leu 
        35                  40                  45              


Ile Pro Thr His Thr Gln Pro Ser Tyr Arg Phe Lys Ala Asn Asn Asn 
    50                  55                  60                  


Asp Ser Gly Glu Tyr Thr Cys Gln Thr Gly Gln Thr Ser Leu Ser Asp 
65                  70                  75                  80  


Pro Val His Leu Thr Val Leu Ser Glu Trp Leu Val Leu Gln Thr Pro 
                85                  90                  95      


His Leu Glu Phe Gln Glu Gly Glu Thr Ile Val Leu Arg Cys His Ser 
            100                 105                 110         


Trp Lys Asp Lys Pro Leu Val Lys Val Thr Phe Phe Gln Asn Gly Lys 
        115                 120                 125             


Ser Lys Lys Phe Ser Arg Ser Asp Pro Asn Phe Ser Ile Pro Gln Ala 
    130                 135                 140                 


Asn His Ser His Ser Gly Asp Tyr His Cys Thr Gly Asn Ile Gly Tyr 
145                 150                 155                 160 


Thr Leu Tyr Ser Ser Lys Pro Val Thr Ile Thr Val Gln Ala Pro Ser 
                165                 170                 175     


Ser Ser Pro Met Gly 
            180     


<210>  449
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  449

Gly Met Arg Thr Glu Asp Leu Pro Lys Ala Val Val Phe Leu Glu Pro 
1               5                   10                  15      


Gln Trp Tyr Arg Val Leu Glu Lys Asp Ser Val Thr Leu Lys Cys Gln 
            20                  25                  30          


Gly Ala Tyr Ser Pro Glu Asp Asn Ser Thr Gln Trp Phe His Asn Glu 
        35                  40                  45              


Ser Leu Ile Ser Ser Gln Ala Ser Ser Tyr Phe Ile Asp Ala Ala Thr 
    50                  55                  60                  


Val Asp Asp Ser Gly Glu Tyr Arg Cys Gln Thr Asn Leu Ser Thr Leu 
65                  70                  75                  80  


Ser Asp Pro Val Gln Leu Glu Val His Ile Gly Trp Leu Leu Leu Gln 
                85                  90                  95      


Ala Pro Arg Trp Val Phe Lys Glu Glu Asp Pro Ile His Leu Arg Cys 
            100                 105                 110         


His Ser Trp Lys Asn Thr Ala Leu His Lys Val Thr Tyr Leu Gln Asn 
        115                 120                 125             


Gly Lys Gly Arg Lys Tyr Phe His His Asn Ser Asp Phe Tyr Ile Pro 
    130                 135                 140                 


Lys Ala Thr Leu Lys Asp Ser Gly Ser Tyr Phe Cys Arg Gly Leu Val 
145                 150                 155                 160 


Gly Ser Lys Asn Val Ser Ser Glu Thr Val Asn Ile Thr Ile Thr Gln 
                165                 170                 175     


Gly Leu Ala Val Ser Thr Ile Ser Ser Phe Phe Pro Pro Gly Tyr Gln 
            180                 185                 190         


<210>  450
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  450

Gly Met Arg Thr Glu Asp Leu Pro Lys Ala Val Val Phe Leu Glu Pro 
1               5                   10                  15      


Gln Trp Tyr Arg Val Leu Glu Lys Asp Ser Val Thr Leu Lys Cys Gln 
            20                  25                  30          


Gly Ala Tyr Ser Pro Glu Asp Asn Ser Thr Gln Trp Phe His Asn Glu 
        35                  40                  45              


Ser Leu Ile Ser Ser Gln Ala Ser Ser Tyr Phe Ile Asp Ala Ala Thr 
    50                  55                  60                  


Val Asp Asp Ser Gly Glu Tyr Arg Cys Gln Thr Asn Leu Ser Thr Leu 
65                  70                  75                  80  


Ser Asp Pro Val Gln Leu Glu Val His Ile Gly Trp Leu Leu Leu Gln 
                85                  90                  95      


Ala Pro Arg Trp Val Phe Lys Glu Glu Asp Pro Ile His Leu Arg Cys 
            100                 105                 110         


His Ser Trp Lys Asn Thr Ala Leu His Lys Val Thr Tyr Leu Gln Asn 
        115                 120                 125             


Gly Lys Gly Arg Lys Tyr Phe His His Asn Ser Asp Phe Tyr Ile Pro 
    130                 135                 140                 


Lys Ala Thr Leu Lys Asp Ser Gly Ser Tyr Phe Cys Arg Gly Leu Val 
145                 150                 155                 160 


Gly Ser Lys Asn Val Ser Ser Glu Thr Val Asn Ile Thr Ile Thr Gln 
                165                 170                 175     


Gly Leu Ser Val Ser Thr Ile Ser Ser Phe Phe Pro Pro Gly Tyr Gln 
            180                 185                 190         


<210>  451
<211>  274
<212>  PRT
<213>  Homo Sapiens

<400>  451

Ala Glu Ser His Leu Ser Leu Leu Tyr His Leu Thr Ala Val Ser Ser 
1               5                   10                  15      


Pro Ala Pro Gly Thr Pro Ala Phe Trp Val Ser Gly Trp Leu Gly Pro 
            20                  25                  30          


Gln Gln Tyr Leu Ser Tyr Asn Ser Leu Arg Gly Glu Ala Glu Pro Cys 
        35                  40                  45              


Gly Ala Trp Val Trp Glu Asn Gln Val Ser Trp Tyr Trp Glu Lys Glu 
    50                  55                  60                  


Thr Thr Asp Leu Arg Ile Lys Glu Lys Leu Phe Leu Glu Ala Phe Lys 
65                  70                  75                  80  


Ala Leu Gly Gly Lys Gly Pro Tyr Thr Leu Gln Gly Leu Leu Gly Cys 
                85                  90                  95      


Glu Leu Gly Pro Asp Asn Thr Ser Val Pro Thr Ala Lys Phe Ala Leu 
            100                 105                 110         


Asn Gly Glu Glu Phe Met Asn Phe Asp Leu Lys Gln Gly Thr Trp Gly 
        115                 120                 125             


Gly Asp Trp Pro Glu Ala Leu Ala Ile Ser Gln Arg Trp Gln Gln Gln 
    130                 135                 140                 


Asp Lys Ala Ala Asn Lys Glu Leu Thr Phe Leu Leu Phe Ser Cys Pro 
145                 150                 155                 160 


His Arg Leu Arg Glu His Leu Glu Arg Gly Arg Gly Asn Leu Glu Trp 
                165                 170                 175     


Lys Glu Pro Pro Ser Met Arg Leu Lys Ala Arg Pro Ser Ser Pro Gly 
            180                 185                 190         


Phe Ser Val Leu Thr Cys Ser Ala Phe Ser Phe Tyr Pro Pro Glu Leu 
        195                 200                 205             


Gln Leu Arg Phe Leu Arg Asn Gly Leu Ala Ala Gly Thr Gly Gln Gly 
    210                 215                 220                 


Asp Phe Gly Pro Asn Ser Asp Gly Ser Phe His Ala Ser Ser Ser Leu 
225                 230                 235                 240 


Thr Val Lys Ser Gly Asp Glu His His Tyr Cys Cys Ile Val Gln His 
                245                 250                 255     


Ala Gly Leu Ala Gln Pro Leu Arg Val Glu Leu Glu Ser Pro Ala Lys 
            260                 265                 270         


Ser Ser 
        


<210>  452
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  452

Arg Ile Leu Pro Glu Val Lys Val Glu Gly Glu Leu Gly Gly Ser Val 
1               5                   10                  15      


Thr Ile Lys Cys Pro Leu Pro Glu Met His Val Arg Ile Tyr Leu Cys 
            20                  25                  30          


Arg Glu Met Ala Gly Ser Gly Thr Cys Gly Thr Val Val Ser Thr Thr 
        35                  40                  45              


Asn Phe Ile Lys Ala Glu Tyr Lys Gly Arg Val Thr Leu Lys Gln Tyr 
    50                  55                  60                  


Pro Arg Lys Asn Leu Phe Leu Val Glu Val Thr Gln Leu Thr Glu Ser 
65                  70                  75                  80  


Asp Ser Gly Val Tyr Ala Cys Gly Ala Gly Met Asn Thr Asp Arg Gly 
                85                  90                  95      


Lys Thr Gln Lys Val Thr Leu Asn Val His Ser Glu Tyr Glu Pro Ser 
            100                 105                 110         


Trp Glu Glu Gln Pro Met Pro Glu Thr Pro Lys Trp Phe His Leu Pro 
        115                 120                 125             


Tyr Leu Phe Gln Met Pro Ala Tyr Ala Ser Ser Ser Lys Phe Val Thr 
    130                 135                 140                 


Arg Val Thr Thr Pro Ala Gln Arg Gly Lys Val Pro Pro Val His His 
145                 150                 155                 160 


Ser Ser Pro Thr Thr Gln Ile Thr His Arg Pro Arg Val Ser Arg Ala 
                165                 170                 175     


Ser Ser Val Ala Gly Asp Lys Pro Arg Thr Phe Leu Pro Ser Thr Thr 
            180                 185                 190         


Ala Ser Lys Ile Ser Ala Leu Glu Gly Leu Leu Lys Pro Gln Thr Pro 
        195                 200                 205             


Ser Tyr Asn His His Thr Arg Leu His Arg Gln Arg Ala Leu Asp Tyr 
    210                 215                 220                 


Gly Ser Gln Ser Gly Arg Glu Gly Gln Gly 
225                 230                 


<210>  453
<211>  291
<212>  PRT
<213>  Homo Sapiens

<400>  453

Ala Glu Leu Phe Leu Ile Ala Ser Pro Ser His Pro Thr Glu Gly Ser 
1               5                   10                  15      


Pro Val Thr Leu Thr Cys Lys Met Pro Phe Leu Gln Ser Ser Asp Ala 
            20                  25                  30          


Gln Phe Gln Phe Cys Phe Phe Arg Asp Thr Arg Ala Leu Gly Pro Gly 
        35                  40                  45              


Trp Ser Ser Ser Pro Lys Leu Gln Ile Ala Ala Met Trp Lys Glu Asp 
    50                  55                  60                  


Thr Gly Ser Tyr Trp Cys Glu Ala Gln Thr Met Ala Ser Lys Val Leu 
65                  70                  75                  80  


Arg Ser Arg Arg Ser Gln Ile Asn Val His Arg Val Pro Val Ala Asp 
                85                  90                  95      


Val Ser Leu Glu Thr Gln Pro Pro Gly Gly Gln Val Met Glu Gly Asp 
            100                 105                 110         


Arg Leu Val Leu Ile Cys Ser Val Ala Met Gly Thr Gly Asp Ile Thr 
        115                 120                 125             


Phe Leu Trp Tyr Lys Gly Ala Val Gly Leu Asn Leu Gln Ser Lys Thr 
    130                 135                 140                 


Gln Arg Ser Leu Thr Ala Glu Tyr Glu Ile Pro Ser Val Arg Glu Ser 
145                 150                 155                 160 


Asp Ala Glu Gln Tyr Tyr Cys Val Ala Glu Asn Gly Tyr Gly Pro Ser 
                165                 170                 175     


Pro Ser Gly Leu Val Ser Ile Thr Val Arg Ile Pro Val Ser Arg Pro 
            180                 185                 190         


Ile Leu Met Leu Arg Ala Pro Arg Ala Gln Ala Ala Val Glu Asp Val 
        195                 200                 205             


Leu Glu Leu His Cys Glu Ala Leu Arg Gly Ser Pro Pro Ile Leu Tyr 
    210                 215                 220                 


Trp Phe Tyr His Glu Asp Ile Thr Leu Gly Ser Arg Ser Ala Pro Ser 
225                 230                 235                 240 


Gly Gly Gly Ala Ser Phe Asn Leu Ser Leu Thr Glu Glu His Ser Gly 
                245                 250                 255     


Asn Tyr Ser Cys Glu Ala Asn Asn Gly Leu Gly Ala Gln Arg Ser Glu 
            260                 265                 270         


Ala Val Thr Leu Asn Phe Thr Val Pro Thr Gly Ala Arg Ser Asn His 
        275                 280                 285             


Leu Thr Ser 
    290     


<210>  454
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  454

Leu Thr Leu Val Ala Pro Ser Ser Val Phe Glu Gly Asp Ser Ile Val 
1               5                   10                  15      


Leu Lys Cys Gln Gly Glu Gln Asn Trp Lys Ile Gln Lys Met Ala Tyr 
            20                  25                  30          


His Lys Asp Asn Lys Glu Leu Ser Val Phe Lys Lys Phe Ser Asp Phe 
        35                  40                  45              


Leu Ile Gln Ser Ala Val Leu Ser Asp Ser Gly Asn Tyr Phe Cys Ser 
    50                  55                  60                  


Thr Lys Gly Gln Leu Phe Leu Trp Asp Lys Thr Ser Asn Ile Val Lys 
65                  70                  75                  80  


Ile Lys Val Gln Gly Pro Asp Gly Tyr Arg Arg Asp Leu Met Thr Ala 
                85                  90                  95      


Gly Val 
        


<210>  455
<211>  556
<212>  PRT
<213>  Homo Sapiens

<400>  455

Gly Val Ala Pro Lys Ala Val Leu Leu Leu Asn Pro Pro Trp Ser Thr 
1               5                   10                  15      


Ala Phe Lys Gly Glu Lys Val Ala Leu Ile Cys Ser Ser Ile Ser His 
            20                  25                  30          


Ser Leu Ala Gln Gly Asp Thr Tyr Trp Tyr His Asp Glu Lys Leu Leu 
        35                  40                  45              


Lys Ile Lys His Asp Lys Ile Gln Ile Thr Glu Pro Gly Asn Tyr Gln 
    50                  55                  60                  


Cys Lys Thr Arg Gly Ser Ser Leu Ser Asp Ala Val His Val Glu Phe 
65                  70                  75                  80  


Ser Pro Asp Trp Leu Ile Leu Gln Ala Leu His Pro Val Phe Glu Gly 
                85                  90                  95      


Asp Asn Val Ile Leu Arg Cys Gln Gly Lys Asp Asn Lys Asn Thr His 
            100                 105                 110         


Gln Lys Val Tyr Tyr Lys Asp Gly Lys Gln Leu Pro Asn Ser Tyr Asn 
        115                 120                 125             


Leu Glu Lys Ile Thr Val Asn Ser Val Ser Arg Asp Asn Ser Lys Tyr 
    130                 135                 140                 


His Cys Thr Ala Tyr Arg Lys Phe Tyr Ile Leu Asp Ile Glu Val Thr 
145                 150                 155                 160 


Ser Lys Pro Leu Asn Ile Gln Val Gln Glu Leu Phe Leu His Pro Val 
                165                 170                 175     


Leu Arg Ala Ser Ser Ser Thr Pro Ile Glu Gly Ser Pro Met Thr Leu 
            180                 185                 190         


Thr Cys Glu Thr Gln Leu Ser Pro Gln Arg Pro Asp Val Gln Leu Gln 
        195                 200                 205             


Phe Ser Leu Phe Arg Asp Ser Gln Thr Leu Gly Leu Gly Trp Ser Arg 
    210                 215                 220                 


Ser Pro Arg Leu Gln Ile Pro Ala Met Trp Thr Glu Asp Ser Gly Ser 
225                 230                 235                 240 


Tyr Trp Cys Glu Val Glu Thr Val Thr His Ser Ile Lys Lys Arg Ser 
                245                 250                 255     


Leu Arg Ser Gln Ile Arg Val Gln Arg Val Pro Val Ser Asn Val Asn 
            260                 265                 270         


Leu Glu Ile Arg Pro Thr Gly Gly Gln Leu Ile Glu Gly Glu Asn Met 
        275                 280                 285             


Val Leu Ile Cys Ser Val Ala Gln Gly Ser Gly Thr Val Thr Phe Ser 
    290                 295                 300                 


Trp His Lys Glu Gly Arg Val Arg Ser Leu Gly Arg Lys Thr Gln Arg 
305                 310                 315                 320 


Ser Leu Leu Ala Glu Leu His Val Leu Thr Val Lys Glu Ser Asp Ala 
                325                 330                 335     


Gly Arg Tyr Tyr Cys Ala Ala Asp Asn Val His Ser Pro Ile Leu Ser 
            340                 345                 350         


Thr Trp Ile Arg Val Thr Val Arg Ile Pro Val Ser His Pro Val Leu 
        355                 360                 365             


Thr Phe Arg Ala Pro Arg Ala His Thr Val Val Gly Asp Leu Leu Glu 
    370                 375                 380                 


Leu His Cys Glu Ser Leu Arg Gly Ser Pro Pro Ile Leu Tyr Arg Phe 
385                 390                 395                 400 


Tyr His Glu Asp Val Thr Leu Gly Asn Ser Ser Ala Pro Ser Gly Gly 
                405                 410                 415     


Gly Ala Ser Phe Asn Leu Ser Leu Thr Ala Glu His Ser Gly Asn Tyr 
            420                 425                 430         


Ser Cys Asp Ala Asp Asn Gly Leu Gly Ala Gln His Ser His Gly Val 
        435                 440                 445             


Ser Leu Arg Val Thr Val Pro Val Ser Arg Pro Val Leu Thr Leu Arg 
    450                 455                 460                 


Ala Pro Gly Ala Gln Ala Val Val Gly Asp Leu Leu Glu Leu His Cys 
465                 470                 475                 480 


Glu Ser Leu Arg Gly Ser Phe Pro Ile Leu Tyr Trp Phe Tyr His Glu 
                485                 490                 495     


Asp Asp Thr Leu Gly Asn Ile Ser Ala His Ser Gly Gly Gly Ala Ser 
            500                 505                 510         


Phe Asn Leu Ser Leu Thr Thr Glu His Ser Gly Asn Tyr Ser Cys Glu 
        515                 520                 525             


Ala Asp Asn Gly Leu Gly Ala Gln His Ser Lys Val Val Thr Leu Asn 
    530                 535                 540                 


Val Thr Gly Thr Ser Arg Asn Arg Thr Gly Leu Thr 
545                 550                 555     


<210>  456
<211>  368
<212>  PRT
<213>  Homo Sapiens

<400>  456

Ala His Lys Pro Val Ile Ser Val His Pro Pro Trp Thr Thr Phe Phe 
1               5                   10                  15      


Lys Gly Glu Arg Val Thr Leu Thr Cys Asn Gly Phe Gln Phe Tyr Ala 
            20                  25                  30          


Thr Glu Lys Thr Thr Trp Tyr His Arg His Tyr Trp Gly Glu Lys Leu 
        35                  40                  45              


Thr Leu Thr Pro Gly Asn Thr Leu Glu Val Arg Glu Ser Gly Leu Tyr 
    50                  55                  60                  


Arg Cys Gln Ala Arg Gly Ser Pro Arg Ser Asn Pro Val Arg Leu Leu 
65                  70                  75                  80  


Phe Ser Ser Asp Ser Leu Ile Leu Gln Ala Pro Tyr Ser Val Phe Glu 
                85                  90                  95      


Gly Asp Thr Leu Val Leu Arg Cys His Arg Arg Arg Lys Glu Lys Leu 
            100                 105                 110         


Thr Ala Val Lys Tyr Thr Trp Asn Gly Asn Ile Leu Ser Ile Ser Asn 
        115                 120                 125             


Lys Ser Trp Asp Leu Leu Ile Pro Gln Ala Ser Ser Asn Asn Asn Gly 
    130                 135                 140                 


Asn Tyr Arg Cys Ile Gly Tyr Gly Asp Glu Asn Asp Val Phe Arg Ser 
145                 150                 155                 160 


Asn Phe Lys Ile Ile Lys Ile Gln Glu Leu Phe Pro His Pro Glu Leu 
                165                 170                 175     


Lys Ala Thr Asp Ser Gln Pro Thr Glu Gly Asn Ser Val Asn Leu Ser 
            180                 185                 190         


Cys Glu Thr Gln Leu Pro Pro Glu Arg Ser Asp Thr Pro Leu His Phe 
        195                 200                 205             


Asn Phe Phe Arg Asp Gly Glu Val Ile Leu Ser Asp Trp Ser Thr Tyr 
    210                 215                 220                 


Pro Glu Leu Gln Leu Pro Thr Val Trp Arg Glu Asn Ser Gly Ser Tyr 
225                 230                 235                 240 


Trp Cys Gly Ala Glu Thr Val Arg Gly Asn Ile His Lys His Ser Pro 
                245                 250                 255     


Ser Leu Gln Ile His Val Gln Arg Ile Pro Val Ser Gly Val Leu Leu 
            260                 265                 270         


Glu Thr Gln Pro Ser Gly Gly Gln Ala Val Glu Gly Glu Met Leu Val 
        275                 280                 285             


Leu Val Cys Ser Val Ala Glu Gly Thr Gly Asp Thr Thr Phe Ser Trp 
    290                 295                 300                 


His Arg Glu Asp Met Gln Glu Ser Leu Gly Arg Lys Thr Gln Arg Ser 
305                 310                 315                 320 


Leu Arg Ala Glu Leu Glu Leu Pro Ala Ile Arg Gln Ser His Ala Gly 
                325                 330                 335     


Gly Tyr Tyr Cys Thr Ala Asp Asn Ser Tyr Gly Pro Val Gln Ser Met 
            340                 345                 350         


Val Leu Asn Val Thr Val Arg Glu Thr Pro Gly Asn Arg Asp Gly Leu 
        355                 360                 365             


<210>  457
<211>  836
<212>  PRT
<213>  Homo Sapiens

<400>  457

Gln Phe Ala Arg Thr Pro Arg Pro Ile Ile Phe Leu Gln Pro Pro Trp 
1               5                   10                  15      


Thr Thr Val Phe Gln Gly Glu Arg Val Thr Leu Thr Cys Lys Gly Phe 
            20                  25                  30          


Arg Phe Tyr Ser Pro Gln Lys Thr Lys Trp Tyr His Arg Tyr Leu Gly 
        35                  40                  45              


Lys Glu Ile Leu Arg Glu Thr Pro Asp Asn Ile Leu Glu Val Gln Glu 
    50                  55                  60                  


Ser Gly Glu Tyr Arg Cys Gln Ala Gln Gly Ser Pro Leu Ser Ser Pro 
65                  70                  75                  80  


Val His Leu Asp Phe Ser Ser Ala Ser Leu Ile Leu Gln Ala Pro Leu 
                85                  90                  95      


Ser Val Phe Glu Gly Asp Ser Val Val Leu Arg Cys Arg Ala Lys Ala 
            100                 105                 110         


Glu Val Thr Leu Asn Asn Thr Ile Tyr Lys Asn Asp Asn Val Leu Ala 
        115                 120                 125             


Phe Leu Asn Lys Arg Thr Asp Phe His Ile Pro His Ala Cys Leu Lys 
    130                 135                 140                 


Asp Asn Gly Ala Tyr Arg Cys Thr Gly Tyr Lys Glu Ser Cys Cys Pro 
145                 150                 155                 160 


Val Ser Ser Asn Thr Val Lys Ile Gln Val Gln Glu Pro Phe Thr Arg 
                165                 170                 175     


Pro Val Leu Arg Ala Ser Ser Phe Gln Pro Ile Ser Gly Asn Pro Val 
            180                 185                 190         


Thr Leu Thr Cys Glu Thr Gln Leu Ser Leu Glu Arg Ser Asp Val Pro 
        195                 200                 205             


Leu Arg Phe Arg Phe Phe Arg Asp Asp Gln Thr Leu Gly Leu Gly Trp 
    210                 215                 220                 


Ser Leu Ser Pro Asn Phe Gln Ile Thr Ala Met Trp Ser Lys Asp Ser 
225                 230                 235                 240 


Gly Phe Tyr Trp Cys Lys Ala Ala Thr Met Pro His Ser Ile Ile Ser 
                245                 250                 255     


Asp Ser Pro Arg Ser Trp Ile Gln Val Gln Ile Pro Ala Ser His Pro 
            260                 265                 270         


Val Leu Thr Leu Ser Pro Glu Lys Ala Leu Asn Phe Glu Gly Thr Lys 
        275                 280                 285             


Val Thr Leu His Cys Glu Thr Gln Glu Asp Ser Leu Arg Thr Leu Tyr 
    290                 295                 300                 


Arg Phe Tyr His Glu Gly Val Pro Leu Arg His Lys Ser Val Arg Cys 
305                 310                 315                 320 


Glu Arg Gly Ala Ser Ile Ser Phe Ser Leu Thr Thr Glu Asn Ser Gly 
                325                 330                 335     


Asn Tyr Tyr Cys Thr Ala Asp Asn Gly Leu Gly Ala Lys Pro Ser Lys 
            340                 345                 350         


Ala Val Ser Leu Ser Val Thr Val Pro Val Ser His Pro Val Leu Asn 
        355                 360                 365             


Leu Ser Ser Pro Glu Asp Leu Ile Phe Glu Gly Ala Lys Val Thr Leu 
    370                 375                 380                 


His Cys Glu Ala Gln Arg Gly Ser Leu Pro Ile Leu Tyr Gln Phe His 
385                 390                 395                 400 


His Glu Asp Ala Ala Leu Glu Arg Arg Ser Ala Asn Ser Ala Gly Gly 
                405                 410                 415     


Val Ala Ile Ser Phe Ser Leu Thr Ala Glu His Ser Gly Asn Tyr Tyr 
            420                 425                 430         


Cys Thr Ala Asp Asn Gly Phe Gly Pro Gln Arg Ser Lys Ala Val Ser 
        435                 440                 445             


Leu Ser Ile Thr Val Pro Val Ser His Pro Val Leu Thr Leu Ser Ser 
    450                 455                 460                 


Ala Glu Ala Leu Thr Phe Glu Gly Ala Thr Val Thr Leu His Cys Glu 
465                 470                 475                 480 


Val Gln Arg Gly Ser Pro Gln Ile Leu Tyr Gln Phe Tyr His Glu Asp 
                485                 490                 495     


Met Pro Leu Trp Ser Ser Ser Thr Pro Ser Val Gly Arg Val Ser Phe 
            500                 505                 510         


Ser Phe Ser Leu Thr Glu Gly His Ser Gly Asn Tyr Tyr Cys Thr Ala 
        515                 520                 525             


Asp Asn Gly Phe Gly Pro Gln Arg Ser Glu Val Val Ser Leu Phe Val 
    530                 535                 540                 


Thr Val Pro Val Ser Arg Pro Ile Leu Thr Leu Arg Val Pro Arg Ala 
545                 550                 555                 560 


Gln Ala Val Val Gly Asp Leu Leu Glu Leu His Cys Glu Ala Pro Arg 
                565                 570                 575     


Gly Ser Pro Pro Ile Leu Tyr Trp Phe Tyr His Glu Asp Val Thr Leu 
            580                 585                 590         


Gly Ser Ser Ser Ala Pro Ser Gly Gly Glu Ala Ser Phe Asn Leu Ser 
        595                 600                 605             


Leu Thr Ala Glu His Ser Gly Asn Tyr Ser Cys Glu Ala Asn Asn Gly 
    610                 615                 620                 


Leu Val Ala Gln His Ser Asp Thr Ile Ser Leu Ser Val Ile Val Pro 
625                 630                 635                 640 


Val Ser Arg Pro Ile Leu Thr Phe Arg Ala Pro Arg Ala Gln Ala Val 
                645                 650                 655     


Val Gly Asp Leu Leu Glu Leu His Cys Glu Ala Leu Arg Gly Ser Ser 
            660                 665                 670         


Pro Ile Leu Tyr Trp Phe Tyr His Glu Asp Val Thr Leu Gly Lys Ile 
        675                 680                 685             


Ser Ala Pro Ser Gly Gly Gly Ala Ser Phe Asn Leu Ser Leu Thr Thr 
    690                 695                 700                 


Glu His Ser Gly Ile Tyr Ser Cys Glu Ala Asp Asn Gly Leu Glu Ala 
705                 710                 715                 720 


Gln Arg Ser Glu Met Val Thr Leu Lys Val Ala Val Pro Val Ser Arg 
                725                 730                 735     


Pro Val Leu Thr Leu Arg Ala Pro Gly Thr His Ala Ala Val Gly Asp 
            740                 745                 750         


Leu Leu Glu Leu His Cys Glu Ala Leu Arg Gly Ser Pro Leu Ile Leu 
        755                 760                 765             


Tyr Arg Phe Phe His Glu Asp Val Thr Leu Gly Asn Arg Ser Ser Pro 
    770                 775                 780                 


Ser Gly Gly Ala Ser Leu Asn Leu Ser Leu Thr Ala Glu His Ser Gly 
785                 790                 795                 800 


Asn Tyr Ser Cys Glu Ala Asp Asn Gly Leu Gly Ala Gln Arg Ser Glu 
                805                 810                 815     


Thr Val Thr Leu Tyr Ile Thr Gly Leu Thr Ala Asn Arg Ser Gly Pro 
            820                 825                 830         


Phe Ala Thr Gly 
        835     


<210>  458
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  458

Leu Tyr Leu Gln Ala Trp Pro Asn Pro Val Phe Glu Gly Asp Ala Leu 
1               5                   10                  15      


Thr Leu Arg Cys Gln Gly Trp Lys Asn Thr Pro Leu Ser Gln Val Lys 
            20                  25                  30          


Phe Tyr Arg Asp Gly Lys Phe Leu His Phe Ser Lys Glu Asn Gln Thr 
        35                  40                  45              


Leu Ser Met Gly Ala Ala Thr Val Gln Ser Arg Gly Gln Tyr Ser Cys 
    50                  55                  60                  


Ser Gly Gln Val Met Tyr Ile Pro Gln Thr Phe Thr Gln Thr Ser Glu 
65                  70                  75                  80  


Thr Ala Met Val Gln Val Gln Glu Leu Phe Pro Pro Pro Val Leu Ser 
                85                  90                  95      


Ala Ile Pro Ser Pro Glu Pro Arg Glu Gly Ser Leu Val Thr Leu Arg 
            100                 105                 110         


Cys Gln Thr Lys Leu His Pro Leu Arg Ser Ala Leu Arg Leu Leu Phe 
        115                 120                 125             


Ser Phe His Lys Asp Gly His Thr Leu Gln Asp Arg Gly Pro His Pro 
    130                 135                 140                 


Glu Leu Cys Ile Pro Gly Ala Lys Glu Gly Asp Ser Gly Leu Tyr Trp 
145                 150                 155                 160 


Cys Glu Val Ala Pro Glu Gly Gly Gln Val Gln Lys Gln Ser Pro Gln 
                165                 170                 175     


Leu Glu Val Arg Val Gln Ala Pro Val Ser Arg Pro Val Leu Thr Leu 
            180                 185                 190         


His His Gly Pro Ala Asp Pro Ala Val Gly Asp Met Val Gln Leu Leu 
        195                 200                 205             


Cys Glu Ala Gln Arg Gly Ser Pro Pro Ile Leu Tyr Ser Phe Tyr Leu 
    210                 215                 220                 


Asp Glu Lys Ile Val Gly Asn His Ser Ala Pro Cys Gly Gly Thr Thr 
225                 230                 235                 240 


Ser Leu Leu Phe Pro Val Lys Ser Glu Gln Asp Ala Gly Asn Tyr Ser 
                245                 250                 255     


Cys Glu Ala Glu Asn Ser Val Ser Arg Glu Arg Ser Glu Pro Lys Lys 
            260                 265                 270         


Leu Ser Leu Lys Gly Ser Gln Val Leu Phe Thr Pro Ala Ser Asn Trp 
        275                 280                 285             


<210>  459
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  459

Ala Thr Leu Glu Lys Pro Ile Leu Ser Leu His Pro Pro Trp Thr Thr 
1               5                   10                  15      


Ile Phe Lys Gly Glu Arg Val Thr Leu Lys Cys Asp Gly Tyr His Pro 
            20                  25                  30          


Leu Leu Leu Glu Leu Gln Pro Ile Ser Thr Leu Trp Tyr Leu Gly His 
        35                  40                  45              


Leu Leu Leu Pro Ser His Lys Lys Ser Ile Glu Val Gln Thr Pro Gly 
    50                  55                  60                  


Val Tyr Arg Cys Gln Thr Arg Gly Ala Pro Val Ser Asp Pro Ile His 
65                  70                  75                  80  


Leu Ser Val Ser Asn Asp Trp Leu Ile Leu Gln Val Pro Tyr Ala Pro 
                85                  90                  95      


Val Phe Glu Gly Glu Pro Leu Val Leu Arg Cys Arg Gly Trp Tyr Asp 
            100                 105                 110         


Lys Val Val Tyr Lys Leu His Tyr Tyr His Asp Gly Gln Ala Val Arg 
        115                 120                 125             


Tyr Phe His Ser Ser Ala Asn Tyr Thr Val Leu Gln Ala Arg Ala Ser 
    130                 135                 140                 


Asp Ser Gly Arg Tyr Gln Cys Ser Gly Thr Met Arg Ile Pro Val Glu 
145                 150                 155                 160 


Ser Ala Pro Met Phe Ser Ala Lys Val Ala Val Thr Val Gln Glu Leu 
                165                 170                 175     


Phe Arg Ala Pro Val Leu Arg Val Met Gly Pro Arg Glu Ala Arg Gly 
            180                 185                 190         


Ala Ala Leu Gly Gly Val Val Leu Arg Cys Asp Thr Arg Leu His Pro 
        195                 200                 205             


Gln Lys Arg Asp Thr Pro Leu Gln Phe Ala Phe Tyr Lys Tyr Ser Arg 
    210                 215                 220                 


Ala Val Arg Arg Phe Asp Trp Gly Ala Glu Tyr Thr Val Pro Glu Pro 
225                 230                 235                 240 


Glu Val Glu Glu Leu Glu Ser Tyr Trp Cys Glu Ala Ala Thr Ala Thr 
                245                 250                 255     


Arg Ser Val Arg Lys Arg Ser Pro Trp Leu Gln Leu Pro Gly Pro Gly 
            260                 265                 270         


Ser Pro Leu Asp Pro Ala Ser Thr Thr Ala Pro Ala Pro Trp Ala Ala 
        275                 280                 285             


Ala Leu Ala Pro Gly Asn Arg Pro Leu Ser Phe Arg Lys Pro Pro Val 
    290                 295                 300                 


Ser Arg Ser Val Pro Leu Val Thr Ser Val Arg Asn Thr Thr Ser Thr 
305                 310                 315                 320 


Gly Leu Gln Phe Pro Ala Ser Gly Ala Pro Thr Ala Gly Pro Pro Ala 
                325                 330                 335     


Cys Ala Pro Pro Thr Pro Leu Glu Gln Ser Ala Gly Ala Leu Lys Pro 
            340                 345                 350         


Asp Val Asp Leu Leu Leu Arg Glu Met Gln Leu Leu Lys Gly Leu Leu 
        355                 360                 365             


Ser Arg Val Val Leu Glu Leu Lys Glu Pro Gln Ala Leu Arg Glu Leu 
    370                 375                 380                 


Arg Gly Thr Pro Glu Thr Pro Thr Ser His Phe Ala Val Ser Pro Gly 
385                 390                 395                 400 


Thr Pro Glu Thr Thr Pro Val Glu Ser 
                405                 


<210>  460
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  460

Ala Ser Phe Glu Thr Leu Gln Cys Glu Gly Pro Val Cys Thr Glu Glu 
1               5                   10                  15      


Ser Ser Cys His Thr Glu Asp Asp Leu Thr Asp Ala Arg Glu Ala Gly 
            20                  25                  30          


Phe Gln Val Lys Ala Tyr Thr Phe Ser Glu Pro Phe His Leu Ile Val 
        35                  40                  45              


Ser Tyr Asp Trp Leu Ile Leu Gln Gly Pro Ala Lys Pro Val Phe Glu 
    50                  55                  60                  


Gly Asp Leu Leu Val Leu Arg Cys Gln Ala Trp Gln Asp Trp Pro Leu 
65                  70                  75                  80  


Thr Gln Val Thr Phe Tyr Arg Asp Gly Ser Ala Leu Gly Pro Pro Gly 
                85                  90                  95      


Pro Asn Arg Glu Phe Ser Ile Thr Val Val Gln Lys Ala Asp Ser Gly 
            100                 105                 110         


His Tyr His Cys Ser Gly Ile Phe Gln Ser Pro Gly Pro Gly Ile Pro 
        115                 120                 125             


Glu Thr Ala Ser Val Val Ala Ile Thr Val Gln Glu Leu Phe Pro Ala 
    130                 135                 140                 


Pro Ile Leu Arg Ala Val Pro Ser Ala Glu Pro Gln Ala Gly Ser Pro 
145                 150                 155                 160 


Met Thr Leu Ser Cys Gln Thr Lys Leu Pro Leu Gln Arg Ser Ala Ala 
                165                 170                 175     


Arg Leu Leu Phe Ser Phe Tyr Lys Asp Gly Arg Ile Val Gln Ser Arg 
            180                 185                 190         


Gly Leu Ser Ser Glu Phe Gln Ile Pro Thr Ala Ser Glu Asp His Ser 
        195                 200                 205             


Gly Ser Tyr Trp Cys Glu Ala Ala Thr Glu Asp Asn Gln Val Trp Lys 
    210                 215                 220                 


Gln Ser Pro Gln Leu Glu Ile Arg Val Gln Gly Ala Ser Ser Ser Ala 
225                 230                 235                 240 


Ala Pro Pro Thr Leu Asn Pro Ala Pro Gln Lys Ser Ala Ala Pro Gly 
                245                 250                 255     


Thr Ala Pro Glu Glu Ala Pro Gly Pro Leu Pro Pro Pro Pro Thr Pro 
            260                 265                 270         


Ser Ser Glu Asp Pro Gly Phe Ser Ser Pro Leu Gly Met Pro Asp Pro 
        275                 280                 285             


His Leu Tyr His Gln Met Gly Leu Leu Leu Lys His Met Gln Asp Val 
    290                 295                 300                 


Arg Val Leu Leu Gly His Leu Leu Met Glu Leu Arg Glu Leu Ser Gly 
305                 310                 315                 320 


His Gln Lys Pro Gly Thr Thr Lys Ala Thr Ala Glu 
                325                 330         


<210>  461
<211>  140
<212>  PRT
<213>  Homo Sapiens

<400>  461

Phe Asn Leu Pro Pro Gly Asn Tyr Lys Lys Pro Lys Leu Leu Tyr Cys 
1               5                   10                  15      


Ser Asn Gly Gly His Phe Leu Arg Ile Leu Pro Asp Gly Thr Val Asp 
            20                  25                  30          


Gly Thr Arg Asp Arg Ser Asp Gln His Ile Gln Leu Gln Leu Ser Ala 
        35                  40                  45              


Glu Ser Val Gly Glu Val Tyr Ile Lys Ser Thr Glu Thr Gly Gln Tyr 
    50                  55                  60                  


Leu Ala Met Asp Thr Asp Gly Leu Leu Tyr Gly Ser Gln Thr Pro Asn 
65                  70                  75                  80  


Glu Glu Cys Leu Phe Leu Glu Arg Leu Glu Glu Asn His Tyr Asn Thr 
                85                  90                  95      


Tyr Ile Ser Lys Lys His Ala Glu Lys Asn Trp Phe Val Gly Leu Lys 
            100                 105                 110         


Lys Asn Gly Ser Cys Lys Arg Gly Pro Arg Thr His Tyr Gly Gln Lys 
        115                 120                 125             


Ala Ile Leu Phe Leu Pro Leu Pro Val Ser Ser Asp 
    130                 135                 140 


<210>  462
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  462

Gln Ala Leu Gly Gln Asp Met Val Ser Pro Glu Ala Thr Asn Ser Ser 
1               5                   10                  15      


Ser Ser Ser Phe Ser Ser Pro Ser Ser Ala Gly Arg His Val Arg Ser 
            20                  25                  30          


Tyr Asn His Leu Gln Gly Asp Val Arg Trp Arg Lys Leu Phe Ser Phe 
        35                  40                  45              


Thr Lys Tyr Phe Leu Lys Ile Glu Lys Asn Gly Lys Val Ser Gly Thr 
    50                  55                  60                  


Lys Lys Glu Asn Cys Pro Tyr Ser Ile Leu Glu Ile Thr Ser Val Glu 
65                  70                  75                  80  


Ile Gly Val Val Ala Val Lys Ala Ile Asn Ser Asn Tyr Tyr Leu Ala 
                85                  90                  95      


Met Asn Lys Lys Gly Lys Leu Tyr Gly Ser Lys Glu Phe Asn Asn Asp 
            100                 105                 110         


Cys Lys Leu Lys Glu Arg Ile Glu Glu Asn Gly Tyr Asn Thr Tyr Ala 
        115                 120                 125             


Ser Phe Asn Trp Gln His Asn Gly Arg Gln Met Tyr Val Ala Leu Asn 
    130                 135                 140                 


Gly Lys Gly Ala Pro Arg Arg Gly Gln Lys Thr Arg Arg Lys Asn Thr 
145                 150                 155                 160 


Ser Ala His Phe Leu Pro Met Val Val His Ser 
                165                 170     


<210>  463
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  463

Met Ala Glu Val Gly Gly Val Phe Ala Ser Leu Asp Trp Asp Leu His 
1               5                   10                  15      


Gly Phe Ser Ser Ser Leu Gly Asn Val Pro Leu Ala Asp Ser Pro Gly 
            20                  25                  30          


Phe Leu Asn Glu Arg Leu Gly Gln Ile Glu Gly Lys Leu Gln Arg Gly 
        35                  40                  45              


Ser Pro Thr Asp Phe Ala His Leu Lys Gly Ile Leu Arg Arg Arg Gln 
    50                  55                  60                  


Leu Tyr Cys Arg Thr Gly Phe His Leu Glu Ile Phe Pro Asn Gly Thr 
65                  70                  75                  80  


Val His Gly Thr Arg His Asp His Ser Arg Phe Gly Ile Leu Glu Phe 
                85                  90                  95      


Ile Ser Leu Ala Val Gly Leu Ile Ser Ile Arg Gly Val Asp Ser Gly 
            100                 105                 110         


Leu Tyr Leu Gly Met Asn Glu Arg Gly Glu Leu Tyr Gly Ser Lys Lys 
        115                 120                 125             


Leu Thr Arg Glu Cys Val Phe Arg Glu Gln Phe Glu Glu Asn Trp Tyr 
    130                 135                 140                 


Asn Thr Tyr Ala Ser Thr Leu Tyr Lys His Ser Asp Ser Glu Arg Gln 
145                 150                 155                 160 


Tyr Tyr Val Ala Leu Asn Lys Asp Gly Ser Pro Arg Glu Gly Tyr Arg 
                165                 170                 175     


Thr Lys Arg His Gln Lys Phe Thr His Phe Leu Pro Arg Pro Val Asp 
            180                 185                 190         


Pro Ser Lys Leu Pro Ser Met Ser Arg Asp Leu Phe His Tyr Arg 
        195                 200                 205         


<210>  464
<211>  194
<212>  PRT
<213>  Homo Sapiens

<400>  464

Thr Gln Gly Glu Asn His Pro Ser Pro Asn Phe Asn Gln Tyr Val Arg 
1               5                   10                  15      


Asp Gln Gly Ala Met Thr Asp Gln Leu Ser Arg Arg Gln Ile Arg Glu 
            20                  25                  30          


Tyr Gln Leu Tyr Ser Arg Thr Ser Gly Lys His Val Gln Val Thr Gly 
        35                  40                  45              


Arg Arg Ile Ser Ala Thr Ala Glu Asp Gly Asn Lys Phe Ala Lys Leu 
    50                  55                  60                  


Ile Val Glu Thr Asp Thr Phe Gly Ser Arg Val Arg Ile Lys Gly Ala 
65                  70                  75                  80  


Glu Ser Glu Lys Tyr Ile Cys Met Asn Lys Arg Gly Lys Leu Ile Gly 
                85                  90                  95      


Lys Pro Ser Gly Lys Ser Lys Asp Cys Val Phe Thr Glu Ile Val Leu 
            100                 105                 110         


Glu Asn Asn Tyr Thr Ala Phe Gln Asn Ala Arg His Glu Gly Trp Phe 
        115                 120                 125             


Met Ala Phe Thr Arg Gln Gly Arg Pro Arg Gln Ala Ser Arg Ser Arg 
    130                 135                 140                 


Gln Asn Gln Arg Glu Ala His Phe Ile Lys Arg Leu Tyr Gln Gly Gln 
145                 150                 155                 160 


Leu Pro Phe Pro Asn His Ala Glu Lys Gln Lys Gln Phe Glu Phe Val 
                165                 170                 175     


Gly Ser Ala Pro Thr Arg Arg Thr Lys Arg Thr Arg Arg Pro Gln Pro 
            180                 185                 190         


Leu Thr 
        


<210>  465
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  465

Glu Glu Asn Val Asp Phe Arg Ile His Val Glu Asn Gln Thr Arg Ala 
1               5                   10                  15      


Arg Asp Asp Val Ser Arg Lys Gln Leu Arg Leu Tyr Gln Leu Tyr Ser 
            20                  25                  30          


Arg Thr Ser Gly Lys His Ile Gln Val Leu Gly Arg Arg Ile Ser Ala 
        35                  40                  45              


Arg Gly Glu Asp Gly Asp Lys Tyr Ala Gln Leu Leu Val Glu Thr Asp 
    50                  55                  60                  


Thr Phe Gly Ser Gln Val Arg Ile Lys Gly Lys Glu Thr Glu Phe Tyr 
65                  70                  75                  80  


Leu Cys Met Asn Arg Lys Gly Lys Leu Val Gly Lys Pro Asp Gly Thr 
                85                  90                  95      


Ser Lys Glu Cys Val Phe Ile Glu Lys Val Leu Glu Asn Asn Tyr Thr 
            100                 105                 110         


Ala Leu Met Ser Ala Lys Tyr Ser Gly Trp Tyr Val Gly Phe Thr Lys 
        115                 120                 125             


Lys Gly Arg Pro Arg Lys Gly Pro Lys Thr Arg Glu Asn Gln Gln Asp 
    130                 135                 140                 


Val His Phe Met Lys Arg Tyr Pro Lys Gly Gln Pro Glu Leu Gln Lys 
145                 150                 155                 160 


Pro Phe Lys Tyr Thr Thr Val Thr Lys Arg Ser Arg Arg Ile Arg Pro 
                165                 170                 175     


Thr His Pro Ala 
            180 


<210>  466
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  466

Leu Ala Phe Ser Asp Ala Gly Pro His Val His Tyr Gly Trp Gly Asp 
1               5                   10                  15      


Pro Ile Arg Leu Arg His Leu Tyr Thr Ser Gly Pro His Gly Leu Ser 
            20                  25                  30          


Ser Cys Phe Leu Arg Ile Arg Ala Asp Gly Val Val Asp Cys Ala Arg 
        35                  40                  45              


Gly Gln Ser Ala His Ser Leu Leu Glu Ile Lys Ala Val Ala Leu Arg 
    50                  55                  60                  


Thr Val Ala Ile Lys Gly Val His Ser Val Arg Tyr Leu Cys Met Gly 
65                  70                  75                  80  


Ala Asp Gly Lys Met Gln Gly Leu Leu Gln Tyr Ser Glu Glu Asp Cys 
                85                  90                  95      


Ala Phe Glu Glu Glu Ile Arg Pro Asp Gly Tyr Asn Val Tyr Arg Ser 
            100                 105                 110         


Glu Lys His Arg Leu Pro Val Ser Leu Ser Ser Ala Lys Gln Arg Gln 
        115                 120                 125             


Leu Tyr Lys Asn Arg Gly Phe Leu Pro Leu Ser His Phe Leu Pro Met 
    130                 135                 140                 


Leu Pro Met Val Pro Glu Glu Pro Glu Asp Leu Arg Gly His Leu Glu 
145                 150                 155                 160 


Ser Asp Met Phe Ser Ser Pro Leu Glu Thr Asp Ser Met Asp Pro Phe 
                165                 170                 175     


Gly Leu Val Thr Gly Leu Glu Ala Val Arg Ser Pro Ser Phe Glu Lys 
            180                 185                 190         


<210>  467
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  467

Met Ala Pro Leu Ala Glu Val Gly Gly Phe Leu Gly Gly Leu Glu Gly 
1               5                   10                  15      


Leu Gly Gln Gln Val Gly Ser His Phe Leu Leu Pro Pro Ala Gly Glu 
            20                  25                  30          


Arg Pro Pro Leu Leu Gly Glu Arg Arg Ser Ala Ala Glu Arg Ser Ala 
        35                  40                  45              


Arg Gly Gly Pro Gly Ala Ala Gln Leu Ala His Leu His Gly Ile Leu 
    50                  55                  60                  


Arg Arg Arg Gln Leu Tyr Cys Arg Thr Gly Phe His Leu Gln Ile Leu 
65                  70                  75                  80  


Pro Asp Gly Ser Val Gln Gly Thr Arg Gln Asp His Ser Leu Phe Gly 
                85                  90                  95      


Ile Leu Glu Phe Ile Ser Val Ala Val Gly Leu Val Ser Ile Arg Gly 
            100                 105                 110         


Val Asp Ser Gly Leu Tyr Leu Gly Met Asn Asp Lys Gly Glu Leu Tyr 
        115                 120                 125             


Gly Ser Glu Lys Leu Thr Ser Glu Cys Ile Phe Arg Glu Gln Phe Glu 
    130                 135                 140                 


Glu Asn Trp Tyr Asn Thr Tyr Ser Ser Asn Ile Tyr Lys His Gly Asp 
145                 150                 155                 160 


Thr Gly Arg Arg Tyr Phe Val Ala Leu Asn Lys Asp Gly Thr Pro Arg 
                165                 170                 175     


Asp Gly Ala Arg Ser Lys Arg His Gln Lys Phe Thr His Phe Leu Pro 
            180                 185                 190         


Arg Pro Val Asp Pro Glu Arg Val Pro Glu Leu Tyr Lys Asp Leu Leu 
        195                 200                 205             


Met Tyr Thr 
    210     


<210>  468
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  468

His Pro Ile Pro Asp Ser Ser Pro Leu Leu Gln Phe Gly Gly Gln Val 
1               5                   10                  15      


Arg Gln Arg Tyr Leu Tyr Thr Asp Asp Ala Gln Gln Thr Glu Ala His 
            20                  25                  30          


Leu Glu Ile Arg Glu Asp Gly Thr Val Gly Gly Ala Ala Asp Gln Ser 
        35                  40                  45              


Pro Glu Ser Leu Leu Gln Leu Lys Ala Leu Lys Pro Gly Val Ile Gln 
    50                  55                  60                  


Ile Leu Gly Val Lys Thr Ser Arg Phe Leu Cys Gln Arg Pro Asp Gly 
65                  70                  75                  80  


Ala Leu Tyr Gly Ser Leu His Phe Asp Pro Glu Ala Cys Ser Phe Arg 
                85                  90                  95      


Glu Leu Leu Leu Glu Asp Gly Tyr Asn Val Tyr Gln Ser Glu Ala His 
            100                 105                 110         


Gly Leu Pro Leu His Leu Pro Gly Asn Lys Ser Pro His Arg Asp Pro 
        115                 120                 125             


Ala Pro Arg Gly Pro Ala Arg Phe Leu Pro Leu Pro Gly Leu Pro Pro 
    130                 135                 140                 


Ala Pro Pro Glu Pro Pro Gly Ile Leu Ala Pro Gln Pro Pro Asp Val 
145                 150                 155                 160 


Gly Ser Ser Asp Pro Leu Ser Met Val Gly Pro Ser Gln Gly Arg Ser 
                165                 170                 175     


Pro Ser Tyr Ala Ser 
            180     


<210>  469
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  469

Tyr Pro Asn Ala Ser Pro Leu Leu Gly Ser Ser Trp Gly Gly Leu Ile 
1               5                   10                  15      


His Leu Tyr Thr Ala Thr Ala Arg Asn Ser Tyr His Leu Gln Ile His 
            20                  25                  30          


Lys Asn Gly His Val Asp Gly Ala Pro His Gln Thr Ile Tyr Ser Ala 
        35                  40                  45              


Leu Met Ile Arg Ser Glu Asp Ala Gly Phe Val Val Ile Thr Gly Val 
    50                  55                  60                  


Met Ser Arg Arg Tyr Leu Cys Met Asp Phe Arg Gly Asn Ile Phe Gly 
65                  70                  75                  80  


Ser His Tyr Phe Asp Pro Glu Asn Cys Arg Phe Gln His Gln Thr Leu 
                85                  90                  95      


Glu Asn Gly Tyr Asp Val Tyr His Ser Pro Gln Tyr His Phe Leu Val 
            100                 105                 110         


Ser Leu Gly Arg Ala Lys Arg Ala Phe Leu Pro Gly Met Asn Pro Pro 
        115                 120                 125             


Pro Tyr Ser Gln Phe Leu Ser Arg Arg Asn Glu Ile Pro Leu Ile His 
    130                 135                 140                 


Phe Asn Thr Pro Ile Pro Arg Arg His Thr Arg Ser Ala Glu Asp Asp 
145                 150                 155                 160 


Ser Glu Arg Asp Pro Leu Asn Val Leu Lys Pro Arg Ala Arg Met Thr 
                165                 170                 175     


Pro Ala Pro Ala Ser Cys Ser Gln Glu Leu Pro Ser Ala Glu Asp Asn 
            180                 185                 190         


Ser Pro Met Ala Ser Asp Pro Leu Gly Val Val Arg Gly Gly Arg Val 
        195                 200                 205             


Asn Thr His Ala Gly Gly Thr Gly Pro Glu Gly Cys Arg Pro Phe Ala 
    210                 215                 220                 


Lys Phe Ile 
225         


<210>  470
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  470

Ala Ala Gly Pro Gly Ala Arg Leu Arg Arg Asp Ala Gly Gly Arg Gly 
1               5                   10                  15      


Gly Val Tyr Glu His Leu Gly Gly Ala Pro Arg Arg Arg Lys Leu Tyr 
            20                  25                  30          


Cys Ala Thr Lys Tyr His Leu Gln Leu His Pro Ser Gly Arg Val Asn 
        35                  40                  45              


Gly Ser Leu Glu Asn Ser Ala Tyr Ser Ile Leu Glu Ile Thr Ala Val 
    50                  55                  60                  


Glu Val Gly Ile Val Ala Ile Arg Gly Leu Phe Ser Gly Arg Tyr Leu 
65                  70                  75                  80  


Ala Met Asn Lys Arg Gly Arg Leu Tyr Ala Ser Glu His Tyr Ser Ala 
                85                  90                  95      


Glu Cys Glu Phe Val Glu Arg Ile His Glu Leu Gly Tyr Asn Thr Tyr 
            100                 105                 110         


Ala Ser Arg Leu Tyr Arg Thr Val Ser Ser Thr Pro Gly Ala Arg Arg 
        115                 120                 125             


Gln Pro Ser Ala Glu Arg Leu Trp Tyr Val Ser Val Asn Gly Lys Gly 
    130                 135                 140                 


Arg Pro Arg Arg Gly Phe Lys Thr Arg Arg Thr Gln Lys Ser Ser Leu 
145                 150                 155                 160 


Phe Leu Pro Arg Val Leu Asp His Arg Asp His Glu Met Val Arg Gln 
                165                 170                 175     


Leu Gln Ser Gly Leu Pro Arg Pro Pro Gly Lys Gly Val Gln Pro Arg 
            180                 185                 190         


Arg Arg Arg Gln Lys Gln Ser Pro Asp Asn Leu Glu Pro Ser His Val 
        195                 200                 205             


Gln Ala Ser Arg Leu Gly Ser Gln Leu Glu Ala Ser Ala His 
    210                 215                 220         


<210>  471
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  471

His Gly Glu Lys Arg Leu Ala Pro Lys Gly Gln Pro Gly Pro Ala Ala 
1               5                   10                  15      


Thr Asp Arg Asn Pro Arg Gly Ser Ser Ser Arg Gln Ser Ser Ser Ser 
            20                  25                  30          


Ala Met Ser Ser Ser Ser Ala Ser Ser Ser Pro Ala Ala Ser Leu Gly 
        35                  40                  45              


Ser Gln Gly Ser Gly Leu Glu Gln Ser Ser Phe Gln Trp Ser Pro Ser 
    50                  55                  60                  


Gly Arg Arg Thr Gly Ser Leu Tyr Cys Arg Val Gly Ile Gly Phe His 
65                  70                  75                  80  


Leu Gln Ile Tyr Pro Asp Gly Lys Val Asn Gly Ser His Glu Ala Asn 
                85                  90                  95      


Met Leu Ser Val Leu Glu Ile Phe Ala Val Ser Gln Gly Ile Val Gly 
            100                 105                 110         


Ile Arg Gly Val Phe Ser Asn Lys Phe Leu Ala Met Ser Lys Lys Gly 
        115                 120                 125             


Lys Leu His Ala Ser Ala Lys Phe Thr Asp Asp Cys Lys Phe Arg Glu 
    130                 135                 140                 


Arg Phe Gln Glu Asn Ser Tyr Asn Thr Tyr Ala Ser Ala Ile His Arg 
145                 150                 155                 160 


Thr Glu Lys Thr Gly Arg Glu Trp Tyr Val Ala Leu Asn Lys Arg Gly 
                165                 170                 175     


Lys Ala Lys Arg Gly Cys Ser Pro Arg Val Lys Pro Gln His Ile Ser 
            180                 185                 190         


Thr His Phe Leu Pro Arg Phe Lys Gln Ser Glu Gln Pro Glu Leu Ser 
        195                 200                 205             


Phe Thr Val Thr Val Pro Glu Lys Lys Lys Pro Pro Ser Pro Ile Lys 
    210                 215                 220                 


Pro Lys Ile Pro Leu Ser Ala Pro Arg Lys Asn Thr Asn Ser Val Lys 
225                 230                 235                 240 


Tyr Arg Leu Lys Phe Arg Phe Gly 
                245             


<210>  472
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  472

Ser Pro Ala Gly Thr Arg Ala Asn Asn Thr Leu Leu Asp Ser Arg Gly 
1               5                   10                  15      


Trp Gly Thr Leu Leu Ser Arg Ser Arg Ala Gly Leu Ala Gly Glu Ile 
            20                  25                  30          


Ala Gly Val Asn Trp Glu Ser Gly Tyr Leu Val Gly Ile Lys Arg Gln 
        35                  40                  45              


Arg Arg Leu Tyr Cys Asn Val Gly Ile Gly Phe His Leu Gln Val Leu 
    50                  55                  60                  


Pro Asp Gly Arg Ile Ser Gly Thr His Glu Glu Asn Pro Tyr Ser Leu 
65                  70                  75                  80  


Leu Glu Ile Ser Thr Val Glu Arg Gly Val Val Ser Leu Phe Gly Val 
                85                  90                  95      


Arg Ser Ala Leu Phe Val Ala Met Asn Ser Lys Gly Arg Leu Tyr Ala 
            100                 105                 110         


Thr Pro Ser Phe Gln Glu Glu Cys Lys Phe Arg Glu Thr Leu Leu Pro 
        115                 120                 125             


Asn Asn Tyr Asn Ala Tyr Glu Ser Asp Leu Tyr Gln Gly Thr Tyr Ile 
    130                 135                 140                 


Ala Leu Ser Lys Tyr Gly Arg Val Lys Arg Gly Ser Lys Val Ser Pro 
145                 150                 155                 160 


Ile Met Thr Val Thr His Phe Leu Pro Arg Ile 
                165                 170     


<210>  473
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  473

Cys Asn Asp Met Thr Pro Glu Gln Met Ala Thr Asn Val Asn Cys Ser 
1               5                   10                  15      


Ser Pro Glu Arg His Thr Arg Ser Tyr Asp Tyr Met Glu Gly Gly Asp 
            20                  25                  30          


Ile Arg Val Arg Arg Leu Phe Cys Arg Thr Gln Trp Tyr Leu Arg Ile 
        35                  40                  45              


Asp Lys Arg Gly Lys Val Lys Gly Thr Gln Glu Met Lys Asn Asn Tyr 
    50                  55                  60                  


Asn Ile Met Glu Ile Arg Thr Val Ala Val Gly Ile Val Ala Ile Lys 
65                  70                  75                  80  


Gly Val Glu Ser Glu Phe Tyr Leu Ala Met Asn Lys Glu Gly Lys Leu 
                85                  90                  95      


Tyr Ala Lys Lys Glu Cys Asn Glu Asp Cys Asn Phe Lys Glu Leu Ile 
            100                 105                 110         


Leu Glu Asn His Tyr Asn Thr Tyr Ala Ser Ala Lys Trp Thr His Asn 
        115                 120                 125             


Gly Gly Glu Met Phe Val Ala Leu Asn Gln Lys Gly Ile Pro Val Arg 
    130                 135                 140                 


Gly Lys Lys Thr Lys Lys Glu Gln Lys Thr Ala His Phe Leu Pro Met 
145                 150                 155                 160 


Ala Ile Thr 
            


<210>  474
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  474

Leu Gly Glu Val Gly Asn Tyr Phe Gly Val Gln Asp Ala Val Pro Phe 
1               5                   10                  15      


Gly Asn Val Pro Val Leu Pro Val Asp Ser Pro Val Leu Leu Ser Asp 
            20                  25                  30          


His Leu Gly Gln Ser Glu Ala Gly Gly Leu Pro Arg Gly Pro Ala Val 
        35                  40                  45              


Thr Asp Leu Asp His Leu Lys Gly Ile Leu Arg Arg Arg Gln Leu Tyr 
    50                  55                  60                  


Cys Arg Thr Gly Phe His Leu Glu Ile Phe Pro Asn Gly Thr Ile Gln 
65                  70                  75                  80  


Gly Thr Arg Lys Asp His Ser Arg Phe Gly Ile Leu Glu Phe Ile Ser 
                85                  90                  95      


Ile Ala Val Gly Leu Val Ser Ile Arg Gly Val Asp Ser Gly Leu Tyr 
            100                 105                 110         


Leu Gly Met Asn Glu Lys Gly Glu Leu Tyr Gly Ser Glu Lys Leu Thr 
        115                 120                 125             


Gln Glu Cys Val Phe Arg Glu Gln Phe Glu Glu Asn Trp Tyr Asn Thr 
    130                 135                 140                 


Tyr Ser Ser Asn Leu Tyr Lys His Val Asp Thr Gly Arg Arg Tyr Tyr 
145                 150                 155                 160 


Val Ala Leu Asn Lys Asp Gly Thr Pro Arg Glu Gly Thr Arg Thr Lys 
                165                 170                 175     


Arg His Gln Lys Phe Thr His Phe Leu Pro Arg Pro Val Asp Pro Asp 
            180                 185                 190         


Lys Val Pro Glu Leu Tyr Lys Asp Ile Leu Ser Gln Ser 
        195                 200                 205 


<210>  475
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  475

Lys Lys Lys Val Lys Asn Gly Leu His Ser Lys Val Val Ser Glu Gln 
1               5                   10                  15      


Lys Asp Thr Leu Gly Asn Thr Gln Ile Lys Gln Lys Ser Arg Pro Gly 
            20                  25                  30          


Asn Lys Gly Lys Phe Val Thr Lys Asp Gln Ala Asn Cys Arg Trp Ala 
        35                  40                  45              


Ala Thr Glu Gln Glu Glu Gly Ile Ser Leu Lys Val Glu Cys Thr Gln 
    50                  55                  60                  


Leu Asp His Glu Phe Ser Cys Val Phe Ala Gly Asn Pro Thr Ser Cys 
65                  70                  75                  80  


Leu Lys Leu Lys Asp Glu Arg Val Tyr Trp Lys Gln Val Ala Arg Asn 
                85                  90                  95      


Leu Arg Ser Gln Lys Asp Ile Cys Arg Tyr Ser Lys Thr Ala Val Lys 
            100                 105                 110         


Thr Arg Val Cys Arg Lys Asp Phe Pro Glu Ser Ser Leu Lys Leu Val 
        115                 120                 125             


Ser Ser Thr Leu Phe Gly Asn Thr Lys Pro Arg Lys Glu Lys Thr Glu 
    130                 135                 140                 


Met Ser Pro Arg Glu His Ile Lys Gly Lys Glu Thr Thr Pro Ser Ser 
145                 150                 155                 160 


Leu Ala Val Thr Gln Thr Met Ala Thr Lys Ala Pro Glu Cys Val Glu 
                165                 170                 175     


Asp Pro Asp Met Ala Asn Gln Arg Lys Thr Ala Leu Glu Phe Cys Gly 
            180                 185                 190         


Glu Thr Trp Ser Ser Leu Cys Thr Phe Phe Leu Ser Ile Val Gln Asp 
        195                 200                 205             


Thr Ser Cys 
    210     


<210>  476
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  476

Arg Arg Glu Lys Gly Ala Ala Ser Asn Val Ala Glu Pro Val Pro Gly 
1               5                   10                  15      


Pro Thr Gly Gly Ser Ser Gly Arg Phe Leu Ser Pro Glu Gln His Ala 
            20                  25                  30          


Cys Ser Trp Gln Leu Leu Leu Pro Ala Pro Glu Ala Ala Ala Gly Ser 
        35                  40                  45              


Glu Leu Ala Leu Arg Cys Gln Ser Pro Asp Gly Ala Arg His Gln Cys 
    50                  55                  60                  


Ala Tyr Arg Gly His Pro Glu Arg Cys Ala Ala Tyr Ala Ala Arg Arg 
65                  70                  75                  80  


Ala His Phe Trp Lys Gln Val Leu Gly Gly Leu Arg Lys Lys Arg Arg 
                85                  90                  95      


Pro Cys His Asp Pro Ala Pro Leu Gln Ala Arg Leu Cys Ala Gly Lys 
            100                 105                 110         


Lys Gly His Gly Ala Glu Leu Arg Leu Val Pro Arg Ala Ser Pro Pro 
        115                 120                 125             


Ala Arg Pro Thr Val Ala Gly Phe Ala Gly Glu Ser Lys Pro Arg Ala 
    130                 135                 140                 


Arg Asn Arg Gly Arg Thr Arg Glu Arg Ala Ser Gly Pro Ala Ala Gly 
145                 150                 155                 160 


Thr Pro Pro Pro Gln Ser Ala Pro Pro Lys Glu Asn Pro Ser Glu Arg 
                165                 170                 175     


Lys Thr Asn Glu Gly Lys Arg Lys Ala Ala Leu Val Pro Asn Glu Glu 
            180                 185                 190         


Arg Pro Met Gly Thr Gly Pro Asp Pro Asp Gly Leu Asp Gly Asn Ala 
        195                 200                 205             


Glu Leu Thr Glu Thr Tyr Cys Ala Glu Lys Trp His Ser Leu Cys Asn 
    210                 215                 220                 


Phe Phe Val Asn Phe Trp Asn Gly 
225                 230         


<210>  477
<211>  353
<212>  PRT
<213>  Homo Sapiens

<400>  477

Arg Pro Ser Pro Thr Leu Pro Glu Gln Ala Gln Pro Trp Gly Ala Pro 
1               5                   10                  15      


Val Glu Val Glu Ser Phe Leu Val His Pro Gly Asp Leu Leu Gln Leu 
            20                  25                  30          


Arg Cys Arg Leu Arg Asp Asp Val Gln Ser Ile Asn Trp Leu Arg Asp 
        35                  40                  45              


Gly Val Gln Leu Ala Glu Ser Asn Arg Thr Arg Ile Thr Gly Glu Glu 
    50                  55                  60                  


Val Glu Val Gln Asp Ser Val Pro Ala Asp Ser Gly Leu Tyr Ala Cys 
65                  70                  75                  80  


Val Thr Ser Ser Pro Ser Gly Ser Asp Thr Thr Tyr Phe Ser Val Asn 
                85                  90                  95      


Val Ser Asp Ala Leu Pro Ser Ser Glu Asp Asp Asp Asp Asp Asp Asp 
            100                 105                 110         


Ser Ser Ser Glu Glu Lys Glu Thr Asp Asn Thr Lys Pro Asn Pro Val 
        115                 120                 125             


Ala Pro Tyr Trp Thr Ser Pro Glu Lys Met Glu Lys Lys Leu His Ala 
    130                 135                 140                 


Val Pro Ala Ala Lys Thr Val Lys Phe Lys Cys Pro Ser Ser Gly Thr 
145                 150                 155                 160 


Pro Asn Pro Thr Leu Arg Trp Leu Lys Asn Gly Lys Glu Phe Lys Pro 
                165                 170                 175     


Asp His Arg Ile Gly Gly Tyr Lys Val Arg Tyr Ala Thr Gly Ser Ile 
            180                 185                 190         


Ile Met Asp Ser Val Val Pro Ser Asp Lys Gly Asn Tyr Thr Cys Ile 
        195                 200                 205             


Val Glu Asn Glu Tyr Gly Ser Ile Asn His Thr Tyr Gln Leu Asp Val 
    210                 215                 220                 


Val Glu Arg Ser Pro His Arg Pro Ile Leu Gln Ala Gly Leu Pro Ala 
225                 230                 235                 240 


Asn Lys Thr Val Ala Leu Gly Ser Asn Val Glu Phe Met Cys Lys Val 
                245                 250                 255     


Tyr Ser Asp Pro Gln Pro His Ile Gln Trp Leu Lys His Ile Glu Val 
            260                 265                 270         


Asn Gly Ser Lys Ile Gly Pro Asp Asn Leu Pro Tyr Val Gln Ile Leu 
        275                 280                 285             


Lys Thr Ala Gly Val Asn Thr Thr Asp Lys Glu Met Glu Val Leu His 
    290                 295                 300                 


Leu Arg Asn Val Ser Phe Glu Asp Ala Gly Glu Tyr Thr Cys Leu Ala 
305                 310                 315                 320 


Gly Asn Ser Ile Gly Leu Ser His His Ser Ala Trp Leu Thr Val Leu 
                325                 330                 335     


Glu Ala Leu Glu Glu Arg Pro Ala Val Met Thr Ser Pro Leu Tyr Leu 
            340                 345                 350         


Glu 
    


<210>  478
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  478

Arg Pro Ser Phe Ser Leu Val Glu Asp Thr Thr Leu Glu Pro Glu Gly 
1               5                   10                  15      


Ala Pro Tyr Trp Thr Asn Thr Glu Lys Met Glu Lys Arg Leu His Ala 
            20                  25                  30          


Val Pro Ala Ala Asn Thr Val Lys Phe Arg Cys Pro Ala Gly Gly Asn 
        35                  40                  45              


Pro Met Pro Thr Met Arg Trp Leu Lys Asn Gly Lys Glu Phe Lys Gln 
    50                  55                  60                  


Glu His Arg Ile Gly Gly Tyr Lys Val Arg Asn Gln His Trp Ser Leu 
65                  70                  75                  80  


Ile Met Glu Ser Val Val Pro Ser Asp Lys Gly Asn Tyr Thr Cys Val 
                85                  90                  95      


Val Glu Asn Glu Tyr Gly Ser Ile Asn His Thr Tyr His Leu Asp Val 
            100                 105                 110         


Val Glu Arg Ser Pro His Arg Pro Ile Leu Gln Ala Gly Leu Pro Ala 
        115                 120                 125             


Asn Ala Ser Thr Val Val Gly Gly Asp Val Glu Phe Val Cys Lys Val 
    130                 135                 140                 


Tyr Ser Asp Ala Gln Pro His Ile Gln Trp Ile Lys His Val Glu Lys 
145                 150                 155                 160 


Asn Gly Ser Lys Tyr Gly Pro Asp Gly Leu Pro Tyr Leu Lys Val Leu 
                165                 170                 175     


Lys Ala Ala Gly Val Asn Thr Thr Asp Lys Glu Ile Glu Val Leu Tyr 
            180                 185                 190         


Ile Arg Asn Val Thr Phe Glu Asp Ala Gly Glu Tyr Thr Cys Leu Ala 
        195                 200                 205             


Gly Asn Ser Ile Gly Ile Ser Phe His Ser Ala Trp Leu Thr Val Leu 
    210                 215                 220                 


Pro Ala Pro Gly Arg Glu Lys Glu Ile Thr Ala Ser Pro Asp Tyr Leu 
225                 230                 235                 240 


Glu 
    


<210>  479
<211>  353
<212>  PRT
<213>  Homo Sapiens

<400>  479

Glu Ser Leu Gly Thr Glu Gln Arg Val Val Gly Arg Ala Ala Glu Val 
1               5                   10                  15      


Pro Gly Pro Glu Pro Gly Gln Gln Glu Gln Leu Val Phe Gly Ser Gly 
            20                  25                  30          


Asp Ala Val Glu Leu Ser Cys Pro Pro Pro Gly Gly Gly Pro Met Gly 
        35                  40                  45              


Pro Thr Val Trp Val Lys Asp Gly Thr Gly Leu Val Pro Ser Glu Arg 
    50                  55                  60                  


Val Leu Val Gly Pro Gln Arg Leu Gln Val Leu Asn Ala Ser His Glu 
65                  70                  75                  80  


Asp Ser Gly Ala Tyr Ser Cys Arg Gln Arg Leu Thr Gln Arg Val Leu 
                85                  90                  95      


Cys His Phe Ser Val Arg Val Thr Asp Ala Pro Ser Ser Gly Asp Asp 
            100                 105                 110         


Glu Asp Gly Glu Asp Glu Ala Glu Asp Thr Gly Val Asp Thr Gly Ala 
        115                 120                 125             


Pro Tyr Trp Thr Arg Pro Glu Arg Met Asp Lys Lys Leu Leu Ala Val 
    130                 135                 140                 


Pro Ala Ala Asn Thr Val Arg Phe Arg Cys Pro Ala Ala Gly Asn Pro 
145                 150                 155                 160 


Thr Pro Ser Ile Ser Trp Leu Lys Asn Gly Arg Glu Phe Arg Gly Glu 
                165                 170                 175     


His Arg Ile Gly Gly Ile Lys Leu Arg His Gln Gln Trp Ser Leu Val 
            180                 185                 190         


Met Glu Ser Val Val Pro Ser Asp Arg Gly Asn Tyr Thr Cys Val Val 
        195                 200                 205             


Glu Asn Lys Phe Gly Ser Ile Arg Gln Thr Tyr Thr Leu Asp Val Leu 
    210                 215                 220                 


Glu Arg Ser Pro His Arg Pro Ile Leu Gln Ala Gly Leu Pro Ala Asn 
225                 230                 235                 240 


Gln Thr Ala Val Leu Gly Ser Asp Val Glu Phe His Cys Lys Val Tyr 
                245                 250                 255     


Ser Asp Ala Gln Pro His Ile Gln Trp Leu Lys His Val Glu Val Asn 
            260                 265                 270         


Gly Ser Lys Val Gly Pro Asp Gly Thr Pro Tyr Val Thr Val Leu Lys 
        275                 280                 285             


Thr Ala Gly Ala Asn Thr Thr Asp Lys Glu Leu Glu Val Leu Ser Leu 
    290                 295                 300                 


His Asn Val Thr Phe Glu Asp Ala Gly Glu Tyr Thr Cys Leu Ala Gly 
305                 310                 315                 320 


Asn Ser Ile Gly Phe Ser His His Ser Ala Trp Leu Val Val Leu Pro 
                325                 330                 335     


Ala Glu Glu Glu Leu Val Glu Ala Asp Glu Ala Gly Ser Val Tyr Ala 
            340                 345                 350         


Gly 
    


<210>  480
<211>  348
<212>  PRT
<213>  Homo Sapiens

<400>  480

Leu Glu Ala Ser Glu Glu Val Glu Leu Glu Pro Cys Leu Ala Pro Ser 
1               5                   10                  15      


Leu Glu Gln Gln Glu Gln Glu Leu Thr Val Ala Leu Gly Gln Pro Val 
            20                  25                  30          


Arg Leu Cys Cys Gly Arg Ala Glu Arg Gly Gly His Trp Tyr Lys Glu 
        35                  40                  45              


Gly Ser Arg Leu Ala Pro Ala Gly Arg Val Arg Gly Trp Arg Gly Arg 
    50                  55                  60                  


Leu Glu Ile Ala Ser Phe Leu Pro Glu Asp Ala Gly Arg Tyr Leu Cys 
65                  70                  75                  80  


Leu Ala Arg Gly Ser Met Ile Val Leu Gln Asn Leu Thr Leu Ile Thr 
                85                  90                  95      


Gly Asp Ser Leu Thr Ser Ser Asn Asp Asp Glu Asp Pro Lys Ser His 
            100                 105                 110         


Arg Asp Pro Ser Asn Arg His Ser Tyr Pro Gln Gln Ala Pro Tyr Trp 
        115                 120                 125             


Thr His Pro Gln Arg Met Glu Lys Lys Leu His Ala Val Pro Ala Gly 
    130                 135                 140                 


Asn Thr Val Lys Phe Arg Cys Pro Ala Ala Gly Asn Pro Thr Pro Thr 
145                 150                 155                 160 


Ile Arg Trp Leu Lys Asp Gly Gln Ala Phe His Gly Glu Asn Arg Ile 
                165                 170                 175     


Gly Gly Ile Arg Leu Arg His Gln His Trp Ser Leu Val Met Glu Ser 
            180                 185                 190         


Val Val Pro Ser Asp Arg Gly Thr Tyr Thr Cys Leu Val Glu Asn Ala 
        195                 200                 205             


Val Gly Ser Ile Arg Tyr Asn Tyr Leu Leu Asp Val Leu Glu Arg Ser 
    210                 215                 220                 


Pro His Arg Pro Ile Leu Gln Ala Gly Leu Pro Ala Asn Thr Thr Ala 
225                 230                 235                 240 


Val Val Gly Ser Asp Val Glu Leu Leu Cys Lys Val Tyr Ser Asp Ala 
                245                 250                 255     


Gln Pro His Ile Gln Trp Leu Lys His Ile Val Ile Asn Gly Ser Ser 
            260                 265                 270         


Phe Gly Ala Asp Gly Phe Pro Tyr Val Gln Val Leu Lys Thr Ala Asp 
        275                 280                 285             


Ile Asn Ser Ser Glu Val Glu Val Leu Tyr Leu Arg Asn Val Ser Ala 
    290                 295                 300                 


Glu Asp Ala Gly Glu Tyr Thr Cys Leu Ala Gly Asn Ser Ile Gly Leu 
305                 310                 315                 320 


Ser Tyr Gln Ser Ala Trp Leu Thr Val Leu Pro Glu Glu Asp Pro Thr 
                325                 330                 335     


Trp Thr Ala Ala Ala Pro Glu Ala Arg Tyr Thr Asp 
            340                 345             


<210>  481
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  481

Ala Arg Gly Pro Pro Lys Met Ala Asp Lys Val Val Pro Arg Gln Val 
1               5                   10                  15      


Ala Arg Leu Gly Arg Thr Val Arg Leu Gln Cys Pro Val Glu Gly Asp 
            20                  25                  30          


Pro Pro Pro Leu Thr Met Trp Thr Lys Asp Gly Arg Thr Ile His Ser 
        35                  40                  45              


Gly Trp Ser Arg Phe Arg Val Leu Pro Gln Gly Leu Lys Val Lys Gln 
    50                  55                  60                  


Val Glu Arg Glu Asp Ala Gly Val Tyr Val Cys Lys Ala Thr Asn Gly 
65                  70                  75                  80  


Phe Gly Ser Leu Ser Val Asn Tyr Thr Leu Val Val Leu Asp Asp Ile 
                85                  90                  95      


Ser Pro Gly Lys Glu Ser Leu Gly Pro Asp Ser Ser Ser Gly Gly Gln 
            100                 105                 110         


Glu Asp Pro Ala Ser Gln Gln Trp Ala Arg Pro Arg Phe Thr Gln Pro 
        115                 120                 125             


Ser Lys Met Arg Arg Arg Val Ile Ala Arg Pro Val Gly Ser Ser Val 
    130                 135                 140                 


Arg Leu Lys Cys Val Ala Ser Gly His Pro Arg Pro Asp Ile Thr Trp 
145                 150                 155                 160 


Met Lys Asp Asp Gln Ala Leu Thr Arg Pro Glu Ala Ala Glu Pro Arg 
                165                 170                 175     


Lys Lys Lys Trp Thr Leu Ser Leu Lys Asn Leu Arg Pro Glu Asp Ser 
            180                 185                 190         


Gly Lys Tyr Thr Cys Arg Val Ser Asn Arg Ala Gly Ala Ile Asn Ala 
        195                 200                 205             


Thr Tyr Lys Val Asp Val Ile Gln Arg Thr Arg Ser Lys Pro Val Leu 
    210                 215                 220                 


Thr Gly Thr His Pro Val Asn Thr Thr Val Asp Phe Gly Gly Thr Thr 
225                 230                 235                 240 


Ser Phe Gln Cys Lys Val Arg Ser Asp Val Lys Pro Val Ile Gln Trp 
                245                 250                 255     


Leu Lys Arg Val Glu Tyr Gly Ala Glu Gly Arg His Asn Ser Thr Ile 
            260                 265                 270         


Asp Val Gly Gly Gln Lys Phe Val Val Leu Pro Thr Gly Asp Val Trp 
        275                 280                 285             


Ser Arg Pro Asp Gly Ser Tyr Leu Asn Lys Leu Leu Ile Thr Arg Ala 
    290                 295                 300                 


Arg Gln Asp Asp Ala Gly Met Tyr Ile Cys Leu Gly Ala Asn Thr Met 
305                 310                 315                 320 


Gly Tyr Ser Phe Arg Ser Ala Phe Leu Thr Val Leu Pro Asp Pro Lys 
                325                 330                 335     


Pro Pro Gly Pro Pro Val Ala Ser Ser Ser Ser Ala Thr Ser Leu Pro 
            340                 345                 350         


Trp Pro 
        


<210>  482
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  482

Phe Ala Ala Thr Phe Tyr Asp Ile Glu Thr Leu Lys Val Ile Asp Glu 
1               5                   10                  15      


Glu Trp Gln Arg Thr Gln Cys Ser Pro Arg Glu Thr Cys Val Glu Val 
            20                  25                  30          


Ala Ser Glu Leu Gly Lys Ser Thr Asn Thr Phe Phe Lys Pro Pro Cys 
        35                  40                  45              


Val Asn Val Phe Arg Cys Gly Gly Cys Cys Asn Glu Glu Ser Leu Ile 
    50                  55                  60                  


Cys Met Asn Thr Ser Thr Ser Tyr Ile Ser Lys Gln Leu Phe Glu Ile 
65                  70                  75                  80  


Ser Val Pro Leu Thr Ser Val Pro Glu Leu Val Pro Val Lys Val Ala 
                85                  90                  95      


Asn His Thr Gly Cys Lys Cys Leu Pro Thr Ala Pro Arg His Pro Tyr 
            100                 105                 110         


Ser Ile Ile Arg Arg 
        115         


<210>  483
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  483

Thr Leu Gln Val Thr Gln Asp Lys Ile Ile Cys Leu Pro Asn His Glu 
1               5                   10                  15      


Leu Gln Glu Asn Leu Ser Glu Ala Pro Cys Gln Gln Leu Leu Pro Arg 
            20                  25                  30          


Gly Ile Pro Glu Gln Ile Gly Ala Leu Gln Glu Val Lys Gly Leu Lys 
        35                  40                  45              


Asn Asn Leu Asp Leu Gln Gln Tyr Ser Phe Ile Asn Gln Leu Cys Tyr 
    50                  55                  60                  


Glu Thr Ala Leu His Trp Tyr Ala Lys 
65                  70              


<210>  484
<211>  504
<212>  PRT
<213>  Homo Sapiens

<400>  484

Ile Asp Ser Thr Thr Cys Pro Ser Val Cys Arg Cys Asp Asn Gly Phe 
1               5                   10                  15      


Ile Tyr Cys Asn Asp Arg Gly Leu Thr Ser Ile Pro Ala Asp Ile Pro 
            20                  25                  30          


Asp Asp Ala Thr Thr Leu Tyr Leu Gln Asn Asn Gln Ile Asn Asn Ala 
        35                  40                  45              


Gly Ile Pro Gln Asp Leu Lys Thr Lys Val Asn Val Gln Val Ile Tyr 
    50                  55                  60                  


Leu Tyr Glu Asn Asp Leu Asp Glu Phe Pro Ile Asn Leu Pro Arg Ser 
65                  70                  75                  80  


Leu Arg Glu Leu His Leu Gln Asp Asn Asn Val Arg Thr Ile Ala Arg 
                85                  90                  95      


Asp Ser Leu Ala Arg Ile Pro Leu Leu Glu Lys Leu His Leu Asp Asp 
            100                 105                 110         


Asn Ser Val Ser Thr Val Ser Ile Glu Glu Asp Ala Phe Ala Asp Ser 
        115                 120                 125             


Lys Gln Leu Lys Leu Leu Phe Leu Ser Arg Asn His Leu Ser Ser Ile 
    130                 135                 140                 


Pro Ser Gly Leu Pro His Thr Leu Glu Glu Leu Arg Leu Asp Asp Asn 
145                 150                 155                 160 


Arg Ile Ser Thr Ile Pro Leu His Ala Phe Lys Gly Leu Asn Ser Leu 
                165                 170                 175     


Arg Arg Leu Val Leu Asp Gly Asn Leu Leu Ala Asn Gln Arg Ile Ala 
            180                 185                 190         


Asp Asp Thr Phe Ser Arg Leu Gln Asn Leu Thr Glu Leu Ser Leu Val 
        195                 200                 205             


Arg Asn Ser Leu Ala Ala Pro Pro Leu Asn Leu Pro Ser Ala His Leu 
    210                 215                 220                 


Gln Lys Leu Tyr Leu Gln Asp Asn Ala Ile Ser His Ile Pro Tyr Asn 
225                 230                 235                 240 


Thr Leu Ala Lys Met Arg Glu Leu Glu Arg Leu Asp Leu Ser Asn Asn 
                245                 250                 255     


Asn Leu Thr Thr Leu Pro Arg Gly Leu Phe Asp Asp Leu Gly Asn Leu 
            260                 265                 270         


Ala Gln Leu Leu Leu Arg Asn Asn Pro Trp Phe Cys Gly Cys Asn Leu 
        275                 280                 285             


Met Trp Leu Arg Asp Trp Val Lys Ala Arg Ala Ala Val Val Asn Val 
    290                 295                 300                 


Arg Gly Leu Met Cys Gln Gly Pro Glu Lys Val Arg Gly Met Ala Ile 
305                 310                 315                 320 


Lys Asp Ile Thr Ser Glu Met Asp Glu Cys Phe Glu Thr Gly Pro Gln 
                325                 330                 335     


Gly Gly Val Ala Asn Ala Ala Ala Lys Thr Thr Ala Ser Asn His Ala 
            340                 345                 350         


Ser Ala Thr Thr Pro Gln Gly Ser Leu Phe Thr Leu Lys Ala Lys Arg 
        355                 360                 365             


Pro Gly Leu Arg Leu Pro Asp Ser Asn Ile Asp Tyr Pro Met Ala Thr 
    370                 375                 380                 


Gly Asp Gly Ala Lys Thr Leu Ala Ile His Val Lys Ala Leu Thr Ala 
385                 390                 395                 400 


Asp Ser Ile Arg Ile Thr Trp Lys Ala Thr Leu Pro Ala Ser Ser Phe 
                405                 410                 415     


Arg Leu Ser Trp Leu Arg Leu Gly His Ser Pro Ala Val Gly Ser Ile 
            420                 425                 430         


Thr Glu Thr Leu Val Gln Gly Asp Lys Thr Glu Tyr Leu Leu Thr Ala 
        435                 440                 445             


Leu Glu Pro Lys Ser Thr Tyr Ile Ile Cys Met Val Thr Met Glu Thr 
    450                 455                 460                 


Ser Asn Ala Tyr Val Ala Asp Glu Thr Pro Val Cys Ala Lys Ala Glu 
465                 470                 475                 480 


Thr Ala Asp Ser Tyr Gly Pro Thr Thr Thr Leu Asn Gln Glu Gln Asn 
                485                 490                 495     


Ala Gly Pro Met Ala Ser Leu Pro 
            500                 


<210>  485
<211>  506
<212>  PRT
<213>  Homo Sapiens

<400>  485

Cys Pro Ser Val Cys Arg Cys Asp Arg Asn Phe Val Tyr Cys Asn Glu 
1               5                   10                  15      


Arg Ser Leu Thr Ser Val Pro Leu Gly Ile Pro Glu Gly Val Thr Val 
            20                  25                  30          


Leu Tyr Leu His Asn Asn Gln Ile Asn Asn Ala Gly Phe Pro Ala Glu 
        35                  40                  45              


Leu His Asn Val Gln Ser Val His Thr Val Tyr Leu Tyr Gly Asn Gln 
    50                  55                  60                  


Leu Asp Glu Phe Pro Met Asn Leu Pro Lys Asn Val Arg Val Leu His 
65                  70                  75                  80  


Leu Gln Glu Asn Asn Ile Gln Thr Ile Ser Arg Ala Ala Leu Ala Gln 
                85                  90                  95      


Leu Leu Lys Leu Glu Glu Leu His Leu Asp Asp Asn Ser Ile Ser Thr 
            100                 105                 110         


Val Gly Val Glu Asp Gly Ala Phe Arg Glu Ala Ile Ser Leu Lys Leu 
        115                 120                 125             


Leu Phe Leu Ser Lys Asn His Leu Ser Ser Val Pro Val Gly Leu Pro 
    130                 135                 140                 


Val Asp Leu Gln Glu Leu Arg Val Asp Glu Asn Arg Ile Ala Val Ile 
145                 150                 155                 160 


Ser Asp Met Ala Phe Gln Asn Leu Thr Ser Leu Glu Arg Leu Ile Val 
                165                 170                 175     


Asp Gly Asn Leu Leu Thr Asn Lys Gly Ile Ala Glu Gly Thr Phe Ser 
            180                 185                 190         


His Leu Thr Lys Leu Lys Glu Phe Ser Ile Val Arg Asn Ser Leu Ser 
        195                 200                 205             


His Pro Pro Pro Asp Leu Pro Gly Thr His Leu Ile Arg Leu Tyr Leu 
    210                 215                 220                 


Gln Asp Asn Gln Ile Asn His Ile Pro Leu Thr Ala Phe Ser Asn Leu 
225                 230                 235                 240 


Arg Lys Leu Glu Arg Leu Asp Ile Ser Asn Asn Gln Leu Arg Met Leu 
                245                 250                 255     


Thr Gln Gly Val Phe Asp Asn Leu Ser Asn Leu Lys Gln Leu Thr Ala 
            260                 265                 270         


Arg Asn Asn Pro Trp Phe Cys Asp Cys Ser Ile Lys Trp Val Thr Glu 
        275                 280                 285             


Trp Leu Lys Tyr Ile Pro Ser Ser Leu Asn Val Arg Gly Phe Met Cys 
    290                 295                 300                 


Gln Gly Pro Glu Gln Val Arg Gly Met Ala Val Arg Glu Leu Asn Met 
305                 310                 315                 320 


Asn Leu Leu Ser Cys Pro Thr Thr Thr Pro Gly Leu Pro Leu Phe Thr 
                325                 330                 335     


Pro Ala Pro Ser Thr Ala Ser Pro Thr Thr Gln Pro Pro Thr Leu Ser 
            340                 345                 350         


Ile Pro Asn Pro Ser Arg Ser Tyr Thr Pro Pro Thr Pro Thr Thr Ser 
        355                 360                 365             


Lys Leu Pro Thr Ile Pro Asp Trp Asp Gly Arg Glu Arg Val Thr Pro 
    370                 375                 380                 


Pro Ile Ser Glu Arg Ile Gln Leu Ser Ile His Phe Val Asn Asp Thr 
385                 390                 395                 400 


Ser Ile Gln Val Ser Trp Leu Ser Leu Phe Thr Val Met Ala Tyr Lys 
                405                 410                 415     


Leu Thr Trp Val Lys Met Gly His Ser Leu Val Gly Gly Ile Val Gln 
            420                 425                 430         


Glu Arg Ile Val Ser Gly Glu Lys Gln His Leu Ser Leu Val Asn Leu 
        435                 440                 445             


Glu Pro Arg Ser Thr Tyr Arg Ile Cys Leu Val Pro Leu Asp Ala Phe 
    450                 455                 460                 


Asn Tyr Arg Ala Val Glu Asp Thr Ile Cys Ser Glu Ala Thr Thr His 
465                 470                 475                 480 


Ala Ser Tyr Leu Asn Asn Gly Ser Asn Thr Ala Ser Ser His Glu Gln 
                485                 490                 495     


Thr Thr Ser His Ser Met Gly Ser Pro Phe 
            500                 505     


<210>  486
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  486

Lys Ser Cys Pro Ser Val Cys Arg Cys Asp Ala Gly Phe Ile Tyr Cys 
1               5                   10                  15      


Asn Asp Arg Phe Leu Thr Ser Ile Pro Thr Gly Ile Pro Glu Asp Ala 
            20                  25                  30          


Thr Thr Leu Tyr Leu Gln Asn Asn Gln Ile Asn Asn Ala Gly Ile Pro 
        35                  40                  45              


Ser Asp Leu Lys Asn Leu Leu Lys Val Glu Arg Ile Tyr Leu Tyr His 
    50                  55                  60                  


Asn Ser Leu Asp Glu Phe Pro Thr Asn Leu Pro Lys Tyr Val Lys Glu 
65                  70                  75                  80  


Leu His Leu Gln Glu Asn Asn Ile Arg Thr Ile Thr Tyr Asp Ser Leu 
                85                  90                  95      


Ser Lys Ile Pro Tyr Leu Glu Glu Leu His Leu Asp Asp Asn Ser Val 
            100                 105                 110         


Ser Ala Val Ser Ile Glu Glu Gly Ala Phe Arg Asp Ser Asn Tyr Leu 
        115                 120                 125             


Arg Leu Leu Phe Leu Ser Arg Asn His Leu Ser Thr Ile Pro Trp Gly 
    130                 135                 140                 


Leu Pro Arg Thr Ile Glu Glu Leu Arg Leu Asp Asp Asn Arg Ile Ser 
145                 150                 155                 160 


Thr Ile Ser Ser Pro Ser Leu Gln Gly Leu Thr Ser Leu Lys Arg Leu 
                165                 170                 175     


Val Leu Asp Gly Asn Leu Leu Asn Asn His Gly Leu Gly Asp Lys Val 
            180                 185                 190         


Phe Phe Asn Leu Val Asn Leu Thr Glu Leu Ser Leu Val Arg Asn Ser 
        195                 200                 205             


Leu Thr Ala Ala Pro Val Asn Leu Pro Gly Thr Asn Leu Arg Lys Leu 
    210                 215                 220                 


Tyr Leu Gln Asp Asn His Ile Asn Arg Val Pro Pro Asn Ala Phe Ser 
225                 230                 235                 240 


Tyr Leu Arg Gln Leu Tyr Arg Leu Asp Met Ser Asn Asn Asn Leu Ser 
                245                 250                 255     


Asn Leu Pro Gln Gly Ile Phe Asp Asp Leu Asp Asn Ile Thr Gln Leu 
            260                 265                 270         


Ile Leu Arg Asn Asn Pro Trp Tyr Cys Gly Cys Lys Met Lys Trp Val 
        275                 280                 285             


Arg Asp Trp Leu Gln Ser Leu Pro Val Lys Val Asn Val Arg Gly Leu 
    290                 295                 300                 


Met Cys Gln Ala Pro Glu Lys Val Arg Gly Met Ala Ile Lys Asp Leu 
305                 310                 315                 320 


Asn Ala Glu Leu Phe Asp Cys Lys Asp Ser Gly Ile Val Ser Thr Ile 
                325                 330                 335     


Gln Ile Thr Thr Ala Ile Pro Asn Thr Val Tyr Pro Ala Gln Gly Gln 
            340                 345                 350         


Trp Pro Ala Pro Val Thr Lys Gln Pro Asp Ile Lys Asn Pro Lys Leu 
        355                 360                 365             


Thr Lys Asp His Gln Thr Thr Gly Ser Pro Ser Arg Lys Thr Ile Thr 
    370                 375                 380                 


Ile Thr Val Lys Ser Val Thr Ser Asp Thr Ile His Ile Ser Trp Lys 
385                 390                 395                 400 


Leu Ala Leu Pro Met Thr Ala Leu Arg Leu Ser Trp Leu Lys Leu Gly 
                405                 410                 415     


His Ser Pro Ala Phe Gly Ser Ile Thr Glu Thr Ile Val Thr Gly Glu 
            420                 425                 430         


Arg Ser Glu Tyr Leu Val Thr Ala Leu Glu Pro Asp Ser Pro Tyr Lys 
        435                 440                 445             


Val Cys Met Val Pro Met Glu Thr Ser Asn Leu Tyr Leu Phe Asp Glu 
    450                 455                 460                 


Thr Pro Val Cys Ile Glu Thr Glu Thr Ala Pro Leu Arg Met Tyr Asn 
465                 470                 475                 480 


Pro Thr Thr Thr Leu Asn Arg Glu Gln Glu Lys Glu Pro Tyr Lys Asn 
                485                 490                 495     


Pro Asn Leu Pro 
            500 


<210>  487
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  487

Ser Lys Leu Lys Asp Pro Glu Leu Ser Leu Lys Gly Thr Gln His Ile 
1               5                   10                  15      


Met Gln Ala Gly Gln Thr Leu His Leu Gln Cys Arg Gly Glu Ala Ala 
            20                  25                  30          


His Lys Trp Ser Leu Pro Glu Met Val Ser Lys Glu Ser Glu Arg Leu 
        35                  40                  45              


Ser Ile Thr Lys Ser Ala Cys Gly Arg Asn Gly Lys Gln Phe Cys Ser 
    50                  55                  60                  


Thr Leu Thr Leu Asn Thr Ala Gln Ala Asn His Thr Gly Phe Tyr Ser 
65                  70                  75                  80  


Cys Lys Tyr Leu Ala Val Pro Thr Ser Lys Lys Lys Glu Thr Glu Ser 
                85                  90                  95      


Ala Ile Tyr Ile Phe Ile Ser Asp Thr Gly Arg Pro Phe Val Glu Met 
            100                 105                 110         


Tyr Ser Glu Ile Pro Glu Ile Ile His Met Thr Glu Gly Arg Glu Leu 
        115                 120                 125             


Val Ile Pro Cys Arg Val Thr Ser Pro Asn Ile Thr Val Thr Leu Lys 
    130                 135                 140                 


Lys Phe Pro Leu Asp Thr Leu Ile Pro Asp Gly Lys Arg Ile Ile Trp 
145                 150                 155                 160 


Asp Ser Arg Lys Gly Phe Ile Ile Ser Asn Ala Thr Tyr Lys Glu Ile 
                165                 170                 175     


Gly Leu Leu Thr Cys Glu Ala Thr Val Asn Gly His Leu Tyr Lys Thr 
            180                 185                 190         


Asn Tyr Leu Thr His Arg Gln Thr Asn Thr Ile Ile Asp Val Gln Ile 
        195                 200                 205             


Ser Thr Pro Arg Pro Val Lys Leu Leu Arg Gly His Thr Leu Val Leu 
    210                 215                 220                 


Asn Cys Thr Ala Thr Thr Pro Leu Asn Thr Arg Val Gln Met Thr Trp 
225                 230                 235                 240 


Ser Tyr Pro Asp Glu Lys Asn Lys Arg Ala Ser Val Arg Arg Arg Ile 
                245                 250                 255     


Asp Gln Ser Asn Ser His Ala Asn Ile Phe Tyr Ser Val Leu Thr Ile 
            260                 265                 270         


Asp Lys Met Gln Asn Lys Asp Lys Gly Leu Tyr Thr Cys Arg Val Arg 
        275                 280                 285             


Ser Gly Pro Ser Phe Lys Ser Val Asn Thr Ser Val His Ile Tyr Asp 
    290                 295                 300                 


Lys Ala Phe Ile Thr Val Lys His Arg Lys Gln Gln Val Leu Glu Thr 
305                 310                 315                 320 


Val Ala Gly Lys Arg Ser Tyr Arg Leu Ser Met Lys Val Lys Ala Phe 
                325                 330                 335     


Pro Ser Pro Glu Val Val Trp Leu Lys Asp Gly Leu Pro Ala Thr Glu 
            340                 345                 350         


Lys Ser Ala Arg Tyr Leu Thr Arg Gly Tyr Ser Leu Ile Ile Lys Asp 
        355                 360                 365             


Val Thr Glu Glu Asp Ala Gly Asn Tyr Thr Ile Leu Leu Ser Ile Lys 
    370                 375                 380                 


Gln Ser Asn Val Phe Lys Asn Leu Thr Ala Thr Leu Ile Val Asn Val 
385                 390                 395                 400 


Lys Pro Gln Ile Tyr Glu Lys Ala Val Ser Ser Phe Pro Asp Pro Ala 
                405                 410                 415     


Leu Tyr Pro Leu Gly Ser Arg Gln Ile Leu Thr Cys Thr Ala Tyr Gly 
            420                 425                 430         


Ile Pro Gln Pro Thr Ile Lys Trp Phe Trp His Pro Cys Asn His Asn 
        435                 440                 445             


His Ser Glu Ala Arg Cys Asp Phe Cys Ser Asn Asn Glu Glu Ser Phe 
    450                 455                 460                 


Ile Leu Asp Ala Asp Ser Asn Met Gly Asn Arg Ile Glu Ser Ile Thr 
465                 470                 475                 480 


Gln Arg Met Ala Ile Ile Glu Gly Lys Asn Lys Met Ala Ser Thr Leu 
                485                 490                 495     


Val Val Ala Asp Ser Arg Ile Ser Gly Ile Tyr Ile Cys Ile Ala Ser 
            500                 505                 510         


Asn Lys Val Gly Thr Val Gly Arg Asn Ile Ser Phe Tyr Ile Thr Asp 
        515                 520                 525             


Val Pro Asn Gly Phe His Val Asn Leu Glu Lys Met Pro Thr Glu Gly 
    530                 535                 540                 


Glu Asp Leu Lys Leu Ser Cys Thr Val Asn Lys Phe Leu Tyr Arg Asp 
545                 550                 555                 560 


Val Thr Trp Ile Leu Leu Arg Thr Val Asn Asn Arg Thr Met His Tyr 
                565                 570                 575     


Ser Ile Ser Lys Gln Lys Met Ala Ile Thr Lys Glu His Ser Ile Thr 
            580                 585                 590         


Leu Asn Leu Thr Ile Met Asn Val Ser Leu Gln Asp Ser Gly Thr Tyr 
        595                 600                 605             


Ala Cys Arg Ala Arg Asn Val Tyr Thr Gly Glu Glu Ile Leu Gln Lys 
    610                 615                 620                 


Lys Glu Ile Thr Ile Arg Gly Glu His Cys Asn Lys Lys Ala Val Phe 
625                 630                 635                 640 


Ser Arg Ile Ser Lys Phe Lys Ser Thr Arg Asn Asp Cys Thr Thr Gln 
                645                 650                 655     


Ser Asn Val Lys His 
            660     


<210>  488
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  488

Asn Gln Asp Leu Pro Val Ile Lys Cys Val Leu Ile Asn His Lys Asn 
1               5                   10                  15      


Asn Asp Ser Ser Val Gly Lys Ser Ser Ser Tyr Pro Met Val Ser Glu 
            20                  25                  30          


Ser Pro Glu Asp Leu Gly Cys Ala Leu Arg Pro Gln Ser Ser Gly Thr 
        35                  40                  45              


Val Tyr Glu Ala Ala Ala Val Glu Val Asp Val Ser Ala Ser Ile Thr 
    50                  55                  60                  


Leu Gln Val Leu Val Asp Ala Pro Gly Asn Ile Ser Cys Leu Trp Val 
65                  70                  75                  80  


Phe Lys His Ser Ser Leu Asn Cys Gln Pro His Phe Asp Leu Gln Asn 
                85                  90                  95      


Arg Gly Val Val Ser Met Val Ile Leu Lys Met Thr Glu Thr Gln Ala 
            100                 105                 110         


Gly Glu Tyr Leu Leu Phe Ile Gln Ser Glu Ala Thr Asn Tyr Thr Ile 
        115                 120                 125             


Leu Phe Thr Val Ser Ile Arg Asn Thr Leu Leu Tyr Thr Leu Arg Arg 
    130                 135                 140                 


Pro Tyr Phe Arg Lys Met Glu Asn Gln Asp Ala Leu Val Cys Ile Ser 
145                 150                 155                 160 


Glu Ser Val Pro Glu Pro Ile Val Glu Trp Val Leu Cys Asp Ser Gln 
                165                 170                 175     


Gly Glu Ser Cys Lys Glu Glu Ser Pro Ala Val Val Lys Lys Glu Glu 
            180                 185                 190         


Lys Val Leu His Glu Leu Phe Gly Met Asp Ile Arg Cys Cys Ala Arg 
        195                 200                 205             


Asn Glu Leu Gly Arg Glu Cys Thr Arg Leu Phe Thr Ile Asp Leu Asn 
    210                 215                 220                 


Gln Thr Pro Gln Thr Thr Leu Pro Gln Leu Phe Leu Lys Val Gly Glu 
225                 230                 235                 240 


Pro Leu Trp Ile Arg Cys Lys Ala Val His Val Asn His Gly Phe Gly 
                245                 250                 255     


Leu Thr Trp Glu Leu Glu Asn Lys Ala Leu Glu Glu Gly Asn Tyr Phe 
            260                 265                 270         


Glu Met Ser Thr Tyr Ser Thr Asn Arg Thr Met Ile Arg Ile Leu Phe 
        275                 280                 285             


Ala Phe Val Ser Ser Val Ala Arg Asn Asp Thr Gly Tyr Tyr Thr Cys 
    290                 295                 300                 


Ser Ser Ser Lys His Pro Ser Gln Ser Ala Leu Val Thr Ile Val Glu 
305                 310                 315                 320 


Lys Gly Phe Ile Asn Ala Thr Asn Ser Ser Glu Asp Tyr Glu Ile Asp 
                325                 330                 335     


Gln Tyr Glu Glu Phe Cys Phe Ser Val Arg Phe Lys Ala Tyr Pro Gln 
            340                 345                 350         


Ile Arg Cys Thr Trp Thr Phe Ser Arg Lys Ser Phe Pro Cys Glu Gln 
        355                 360                 365             


Lys Gly Leu Asp Asn Gly Tyr Ser Ile Ser Lys Phe Cys Asn His Lys 
    370                 375                 380                 


His Gln Pro Gly Glu Tyr Ile Phe His Ala Glu Asn Asp Asp Ala Gln 
385                 390                 395                 400 


Phe Thr Lys Met Phe Thr Leu Asn Ile Arg Arg Lys Pro Gln Val Leu 
                405                 410                 415     


Ala Glu Ala Ser Ala Ser Gln Ala Ser Cys Phe Ser Asp Gly Tyr Pro 
            420                 425                 430         


Leu Pro Ser Trp Thr Trp Lys Lys Cys Ser Asp Lys Ser Pro Asn Cys 
        435                 440                 445             


Thr Glu Glu Ile Thr Glu Gly Val Trp Asn Arg Lys Ala Asn Arg Lys 
    450                 455                 460                 


Val Phe Gly Gln Trp Val Ser Ser Ser Thr Leu Asn Met Ser Glu Ala 
465                 470                 475                 480 


Ile Lys Gly Phe Leu Val Lys Cys Cys Ala Tyr Asn Ser Leu Gly Thr 
                485                 490                 495     


Ser Cys Glu Thr Ile Leu Leu Asn Ser Pro Gly Pro Phe Pro Phe Ile 
            500                 505                 510         


Gln Asp Asn Ile Ser 
        515         


<210>  489
<211>  358
<212>  PRT
<213>  Homo Sapiens

<400>  489

Gln Tyr Glu Asp Asp Pro His Trp Trp Phe His Tyr Leu Arg Ser Gln 
1               5                   10                  15      


Gln Ser Thr Tyr Tyr Asp Pro Tyr Asp Pro Tyr Pro Tyr Glu Thr Tyr 
            20                  25                  30          


Glu Pro Tyr Pro Tyr Gly Val Asp Glu Gly Pro Ala Tyr Thr Tyr Gly 
        35                  40                  45              


Ser Pro Ser Pro Pro Asp Pro Arg Asp Cys Pro Gln Glu Cys Asp Cys 
    50                  55                  60                  


Pro Pro Asn Phe Pro Thr Ala Met Tyr Cys Asp Asn Arg Asn Leu Lys 
65                  70                  75                  80  


Tyr Leu Pro Phe Val Pro Ser Arg Met Lys Tyr Val Tyr Phe Gln Asn 
                85                  90                  95      


Asn Gln Ile Thr Ser Ile Gln Glu Gly Val Phe Asp Asn Ala Thr Gly 
            100                 105                 110         


Leu Leu Trp Ile Ala Leu His Gly Asn Gln Ile Thr Ser Asp Lys Val 
        115                 120                 125             


Gly Arg Lys Val Phe Ser Lys Leu Arg His Leu Glu Arg Leu Tyr Leu 
    130                 135                 140                 


Asp His Asn Asn Leu Thr Arg Met Pro Gly Pro Leu Pro Arg Ser Leu 
145                 150                 155                 160 


Arg Glu Leu His Leu Asp His Asn Gln Ile Ser Arg Val Pro Asn Asn 
                165                 170                 175     


Ala Leu Glu Gly Leu Glu Asn Leu Thr Ala Leu Tyr Leu Gln His Asn 
            180                 185                 190         


Glu Ile Gln Glu Val Gly Ser Ser Met Arg Gly Leu Arg Ser Leu Ile 
        195                 200                 205             


Leu Leu Asp Leu Ser Tyr Asn His Leu Arg Lys Val Pro Asp Gly Leu 
    210                 215                 220                 


Pro Ser Ala Leu Glu Gln Leu Tyr Met Glu His Asn Asn Val Tyr Thr 
225                 230                 235                 240 


Val Pro Asp Ser Tyr Phe Arg Gly Ala Pro Lys Leu Leu Tyr Val Arg 
                245                 250                 255     


Leu Ser His Asn Ser Leu Thr Asn Asn Gly Leu Ala Ser Asn Thr Phe 
            260                 265                 270         


Asn Ser Ser Ser Leu Leu Glu Leu Asp Leu Ser Tyr Asn Gln Leu Gln 
        275                 280                 285             


Lys Ile Pro Pro Val Asn Thr Asn Leu Glu Asn Leu Tyr Leu Gln Gly 
    290                 295                 300                 


Asn Arg Ile Asn Glu Phe Ser Ile Ser Ser Phe Cys Thr Val Val Asp 
305                 310                 315                 320 


Val Val Asn Phe Ser Lys Leu Gln Val Leu Arg Leu Asp Gly Asn Glu 
                325                 330                 335     


Ile Lys Arg Ser Ala Met Pro Ala Asp Ala Pro Leu Cys Leu Arg Leu 
            340                 345                 350         


Ala Ser Leu Ile Glu Ile 
        355             


<210>  490
<211>  2145
<212>  PRT
<213>  Homo Sapiens

<400>  490

Gln Ala Gln Gln Met Val Gln Pro Gln Ser Pro Val Ala Val Ser Gln 
1               5                   10                  15      


Ser Lys Pro Gly Cys Tyr Asp Asn Gly Lys His Tyr Gln Ile Asn Gln 
            20                  25                  30          


Gln Trp Glu Arg Thr Tyr Leu Gly Asn Ala Leu Val Cys Thr Cys Tyr 
        35                  40                  45              


Gly Gly Ser Arg Gly Phe Asn Cys Glu Ser Lys Pro Glu Ala Glu Glu 
    50                  55                  60                  


Thr Cys Phe Asp Lys Tyr Thr Gly Asn Thr Tyr Arg Val Gly Asp Thr 
65                  70                  75                  80  


Tyr Glu Arg Pro Lys Asp Ser Met Ile Trp Asp Cys Thr Cys Ile Gly 
                85                  90                  95      


Ala Gly Arg Gly Arg Ile Ser Cys Thr Ile Ala Asn Arg Cys His Glu 
            100                 105                 110         


Gly Gly Gln Ser Tyr Lys Ile Gly Asp Thr Trp Arg Arg Pro His Glu 
        115                 120                 125             


Thr Gly Gly Tyr Met Leu Glu Cys Val Cys Leu Gly Asn Gly Lys Gly 
    130                 135                 140                 


Glu Trp Thr Cys Lys Pro Ile Ala Glu Lys Cys Phe Asp His Ala Ala 
145                 150                 155                 160 


Gly Thr Ser Tyr Val Val Gly Glu Thr Trp Glu Lys Pro Tyr Gln Gly 
                165                 170                 175     


Trp Met Met Val Asp Cys Thr Cys Leu Gly Glu Gly Ser Gly Arg Ile 
            180                 185                 190         


Thr Cys Thr Ser Arg Asn Arg Cys Asn Asp Gln Asp Thr Arg Thr Ser 
        195                 200                 205             


Tyr Arg Ile Gly Asp Thr Trp Ser Lys Lys Asp Asn Arg Gly Asn Leu 
    210                 215                 220                 


Leu Gln Cys Ile Cys Thr Gly Asn Gly Arg Gly Glu Trp Lys Cys Glu 
225                 230                 235                 240 


Arg His Thr Ser Val Gln Thr Thr Ser Ser Gly Ser Gly Pro Phe Thr 
                245                 250                 255     


Asp Val Arg Ala Ala Val Tyr Gln Pro Gln Pro His Pro Gln Pro Pro 
            260                 265                 270         


Pro Tyr Gly His Cys Val Thr Asp Ser Gly Val Val Tyr Ser Val Gly 
        275                 280                 285             


Met Gln Trp Leu Lys Thr Gln Gly Asn Lys Gln Met Leu Cys Thr Cys 
    290                 295                 300                 


Leu Gly Asn Gly Val Ser Cys Gln Glu Thr Ala Val Thr Gln Thr Tyr 
305                 310                 315                 320 


Gly Gly Asn Ser Asn Gly Glu Pro Cys Val Leu Pro Phe Thr Tyr Asn 
                325                 330                 335     


Gly Arg Thr Phe Tyr Ser Cys Thr Thr Glu Gly Arg Gln Asp Gly His 
            340                 345                 350         


Leu Trp Cys Ser Thr Thr Ser Asn Tyr Glu Gln Asp Gln Lys Tyr Ser 
        355                 360                 365             


Phe Cys Thr Asp His Thr Val Leu Val Gln Thr Arg Gly Gly Asn Ser 
    370                 375                 380                 


Asn Gly Ala Leu Cys His Phe Pro Phe Leu Tyr Asn Asn His Asn Tyr 
385                 390                 395                 400 


Thr Asp Cys Thr Ser Glu Gly Arg Arg Asp Asn Met Lys Trp Cys Gly 
                405                 410                 415     


Thr Thr Gln Asn Tyr Asp Ala Asp Gln Lys Phe Gly Phe Cys Pro Met 
            420                 425                 430         


Ala Ala His Glu Glu Ile Cys Thr Thr Asn Glu Gly Val Met Tyr Arg 
        435                 440                 445             


Ile Gly Asp Gln Trp Asp Lys Gln His Asp Met Gly His Met Met Arg 
    450                 455                 460                 


Cys Thr Cys Val Gly Asn Gly Arg Gly Glu Trp Thr Cys Ile Ala Tyr 
465                 470                 475                 480 


Ser Gln Leu Arg Asp Gln Cys Ile Val Asp Asp Ile Thr Tyr Asn Val 
                485                 490                 495     


Asn Asp Thr Phe His Lys Arg His Glu Glu Gly His Met Leu Asn Cys 
            500                 505                 510         


Thr Cys Phe Gly Gln Gly Arg Gly Arg Trp Lys Cys Asp Pro Val Asp 
        515                 520                 525             


Gln Cys Gln Asp Ser Glu Thr Gly Thr Phe Tyr Gln Ile Gly Asp Ser 
    530                 535                 540                 


Trp Glu Lys Tyr Val His Gly Val Arg Tyr Gln Cys Tyr Cys Tyr Gly 
545                 550                 555                 560 


Arg Gly Ile Gly Glu Trp His Cys Gln Pro Leu Gln Thr Tyr Pro Ser 
                565                 570                 575     


Ser Ser Gly Pro Val Glu Val Phe Ile Thr Glu Thr Pro Ser Gln Pro 
            580                 585                 590         


Asn Ser His Pro Ile Gln Trp Asn Ala Pro Gln Pro Ser His Ile Ser 
        595                 600                 605             


Lys Tyr Ile Leu Arg Trp Arg Pro Lys Asn Ser Val Gly Arg Trp Lys 
    610                 615                 620                 


Glu Ala Thr Ile Pro Gly His Leu Asn Ser Tyr Thr Ile Lys Gly Leu 
625                 630                 635                 640 


Lys Pro Gly Val Val Tyr Glu Gly Gln Leu Ile Ser Ile Gln Gln Tyr 
                645                 650                 655     


Gly His Gln Glu Val Thr Arg Phe Asp Phe Thr Thr Thr Ser Thr Ser 
            660                 665                 670         


Thr Pro Val Thr Ser Asn Thr Val Thr Gly Glu Thr Thr Pro Phe Ser 
        675                 680                 685             


Pro Leu Val Ala Thr Ser Glu Ser Val Thr Glu Ile Thr Ala Ser Ser 
    690                 695                 700                 


Phe Val Val Ser Trp Val Ser Ala Ser Asp Thr Val Ser Gly Phe Arg 
705                 710                 715                 720 


Val Glu Tyr Glu Leu Ser Glu Glu Gly Asp Glu Pro Gln Tyr Leu Asp 
                725                 730                 735     


Leu Pro Ser Thr Ala Thr Ser Val Asn Ile Pro Asp Leu Leu Pro Gly 
            740                 745                 750         


Arg Lys Tyr Ile Val Asn Val Tyr Gln Ile Ser Glu Asp Gly Glu Gln 
        755                 760                 765             


Ser Leu Ile Leu Ser Thr Ser Gln Thr Thr Ala Pro Asp Ala Pro Pro 
    770                 775                 780                 


Asp Pro Thr Val Asp Gln Val Asp Asp Thr Ser Ile Val Val Arg Trp 
785                 790                 795                 800 


Ser Arg Pro Gln Ala Pro Ile Thr Gly Tyr Arg Ile Val Tyr Ser Pro 
                805                 810                 815     


Ser Val Glu Gly Ser Ser Thr Glu Leu Asn Leu Pro Glu Thr Ala Asn 
            820                 825                 830         


Ser Val Thr Leu Ser Asp Leu Gln Pro Gly Val Gln Tyr Asn Ile Thr 
        835                 840                 845             


Ile Tyr Ala Val Glu Glu Asn Gln Glu Ser Thr Pro Val Val Ile Gln 
    850                 855                 860                 


Gln Glu Thr Thr Gly Thr Pro Arg Ser Asp Thr Val Pro Ser Pro Arg 
865                 870                 875                 880 


Asp Leu Gln Phe Val Glu Val Thr Asp Val Lys Val Thr Ile Met Trp 
                885                 890                 895     


Thr Pro Pro Glu Ser Ala Val Thr Gly Tyr Arg Val Asp Val Ile Pro 
            900                 905                 910         


Val Asn Leu Pro Gly Glu His Gly Gln Arg Leu Pro Ile Ser Arg Asn 
        915                 920                 925             


Thr Phe Ala Glu Val Thr Gly Leu Ser Pro Gly Val Thr Tyr Tyr Phe 
    930                 935                 940                 


Lys Val Phe Ala Val Ser His Gly Arg Glu Ser Lys Pro Leu Thr Ala 
945                 950                 955                 960 


Gln Gln Thr Thr Lys Leu Asp Ala Pro Thr Asn Leu Gln Phe Val Asn 
                965                 970                 975     


Glu Thr Asp Ser Thr Val Leu Val Arg Trp Thr Pro Pro Arg Ala Gln 
            980                 985                 990         


Ile Thr Gly Tyr Arg Leu Thr Val  Gly Leu Thr Arg Arg  Gly Gln Pro 
        995                 1000                 1005             


Arg Gln  Tyr Asn Val Gly Pro  Ser Val Ser Lys Tyr  Pro Leu Arg 
    1010                 1015                 1020             


Asn Leu  Gln Pro Ala Ser Glu  Tyr Thr Val Ser Leu  Val Ala Ile 
    1025                 1030                 1035             


Lys Gly  Asn Gln Glu Ser Pro  Lys Ala Thr Gly Val  Phe Thr Thr 
    1040                 1045                 1050             


Leu Gln  Pro Gly Ser Ser Ile  Pro Pro Tyr Asn Thr  Glu Val Thr 
    1055                 1060                 1065             


Glu Thr  Thr Ile Val Ile Thr  Trp Thr Pro Ala Pro  Arg Ile Gly 
    1070                 1075                 1080             


Phe Lys  Leu Gly Val Arg Pro  Ser Gln Gly Gly Glu  Ala Pro Arg 
    1085                 1090                 1095             


Glu Val  Thr Ser Asp Ser Gly  Ser Ile Val Val Ser  Gly Leu Thr 
    1100                 1105                 1110             


Pro Gly  Val Glu Tyr Val Tyr  Thr Ile Gln Val Leu  Arg Asp Gly 
    1115                 1120                 1125             


Gln Glu  Arg Asp Ala Pro Ile  Val Asn Lys Val Val  Thr Pro Leu 
    1130                 1135                 1140             


Ser Pro  Pro Thr Asn Leu His  Leu Glu Ala Asn Pro  Asp Thr Gly 
    1145                 1150                 1155             


Val Leu  Thr Val Ser Trp Glu  Arg Ser Thr Thr Pro  Asp Ile Thr 
    1160                 1165                 1170             


Gly Tyr  Arg Ile Thr Thr Thr  Pro Thr Asn Gly Gln  Gln Gly Asn 
    1175                 1180                 1185             


Ser Leu  Glu Glu Val Val His  Ala Asp Gln Ser Ser  Cys Thr Phe 
    1190                 1195                 1200             


Asp Asn  Leu Ser Pro Gly Leu  Glu Tyr Asn Val Ser  Val Tyr Thr 
    1205                 1210                 1215             


Val Lys  Asp Asp Lys Glu Ser  Val Pro Ile Ser Asp  Thr Ile Ile 
    1220                 1225                 1230             


Pro Ala  Val Pro Pro Pro Thr  Asp Leu Arg Phe Thr  Asn Ile Gly 
    1235                 1240                 1245             


Pro Asp  Thr Met Arg Val Thr  Trp Ala Pro Pro Pro  Ser Ile Asp 
    1250                 1255                 1260             


Leu Thr  Asn Phe Leu Val Arg  Tyr Ser Pro Val Lys  Asn Glu Glu 
    1265                 1270                 1275             


Asp Val  Ala Glu Leu Ser Ile  Ser Pro Ser Asp Asn  Ala Val Val 
    1280                 1285                 1290             


Leu Thr  Asn Leu Leu Pro Gly  Thr Glu Tyr Val Val  Ser Val Ser 
    1295                 1300                 1305             


Ser Val  Tyr Glu Gln His Glu  Ser Thr Pro Leu Arg  Gly Arg Gln 
    1310                 1315                 1320             


Lys Thr  Gly Leu Asp Ser Pro  Thr Gly Ile Asp Phe  Ser Asp Ile 
    1325                 1330                 1335             


Thr Ala  Asn Ser Phe Thr Val  His Trp Ile Ala Pro  Arg Ala Thr 
    1340                 1345                 1350             


Ile Thr  Gly Tyr Arg Ile Arg  His His Pro Glu His  Phe Ser Gly 
    1355                 1360                 1365             


Arg Pro  Arg Glu Asp Arg Val  Pro His Ser Arg Asn  Ser Ile Thr 
    1370                 1375                 1380             


Leu Thr  Asn Leu Thr Pro Gly  Thr Glu Tyr Val Val  Ser Ile Val 
    1385                 1390                 1395             


Ala Leu  Asn Gly Arg Glu Glu  Ser Pro Leu Leu Ile  Gly Gln Gln 
    1400                 1405                 1410             


Ser Thr  Val Ser Asp Val Pro  Arg Asp Leu Glu Val  Val Ala Ala 
    1415                 1420                 1425             


Thr Pro  Thr Ser Leu Leu Ile  Ser Trp Asp Ala Pro  Ala Val Thr 
    1430                 1435                 1440             


Val Arg  Tyr Tyr Arg Ile Thr  Tyr Gly Glu Thr Gly  Gly Asn Ser 
    1445                 1450                 1455             


Pro Val  Gln Glu Phe Thr Val  Pro Gly Ser Lys Ser  Thr Ala Thr 
    1460                 1465                 1470             


Ile Ser  Gly Leu Lys Pro Gly  Val Asp Tyr Thr Ile  Thr Val Tyr 
    1475                 1480                 1485             


Ala Val  Thr Gly Arg Gly Asp  Ser Pro Ala Ser Ser  Lys Pro Ile 
    1490                 1495                 1500             


Ser Ile  Asn Tyr Arg Thr Glu  Ile Asp Lys Pro Ser  Gln Met Gln 
    1505                 1510                 1515             


Val Thr  Asp Val Gln Asp Asn  Ser Ile Ser Val Lys  Trp Leu Pro 
    1520                 1525                 1530             


Ser Ser  Ser Pro Val Thr Gly  Tyr Arg Val Thr Thr  Thr Pro Lys 
    1535                 1540                 1545             


Asn Gly  Pro Gly Pro Thr Lys  Thr Lys Thr Ala Gly  Pro Asp Gln 
    1550                 1555                 1560             


Thr Glu  Met Thr Ile Glu Gly  Leu Gln Pro Thr Val  Glu Tyr Val 
    1565                 1570                 1575             


Val Ser  Val Tyr Ala Gln Asn  Pro Ser Gly Glu Ser  Gln Pro Leu 
    1580                 1585                 1590             


Val Gln  Thr Ala Val Thr Thr  Ile Pro Ala Pro Thr  Asp Leu Lys 
    1595                 1600                 1605             


Phe Thr  Gln Val Thr Pro Thr  Ser Leu Ser Ala Gln  Trp Thr Pro 
    1610                 1615                 1620             


Pro Asn  Val Gln Leu Thr Gly  Tyr Arg Val Arg Val  Thr Pro Lys 
    1625                 1630                 1635             


Glu Lys  Thr Gly Pro Met Lys  Glu Ile Asn Leu Ala  Pro Asp Ser 
    1640                 1645                 1650             


Ser Ser  Val Val Val Ser Gly  Leu Met Val Ala Thr  Lys Tyr Glu 
    1655                 1660                 1665             


Val Ser  Val Tyr Ala Leu Lys  Asp Thr Leu Thr Ser  Arg Pro Ala 
    1670                 1675                 1680             


Gln Gly  Val Val Thr Thr Leu  Glu Asn Val Ser Pro  Pro Arg Arg 
    1685                 1690                 1695             


Ala Arg  Val Thr Asp Ala Thr  Glu Thr Thr Ile Thr  Ile Ser Trp 
    1700                 1705                 1710             


Arg Thr  Lys Thr Glu Thr Ile  Thr Gly Phe Gln Val  Asp Ala Val 
    1715                 1720                 1725             


Pro Ala  Asn Gly Gln Thr Pro  Ile Gln Arg Thr Ile  Lys Pro Asp 
    1730                 1735                 1740             


Val Arg  Ser Tyr Thr Ile Thr  Gly Leu Gln Pro Gly  Thr Asp Tyr 
    1745                 1750                 1755             


Lys Ile  Tyr Leu Tyr Thr Leu  Asn Asp Asn Ala Arg  Ser Ser Pro 
    1760                 1765                 1770             


Val Val  Ile Asp Ala Ser Thr  Ala Ile Asp Ala Pro  Ser Asn Leu 
    1775                 1780                 1785             


Arg Phe  Leu Ala Thr Thr Pro  Asn Ser Leu Leu Val  Ser Trp Gln 
    1790                 1795                 1800             


Pro Pro  Arg Ala Arg Ile Thr  Gly Tyr Ile Ile Lys  Tyr Glu Lys 
    1805                 1810                 1815             


Pro Gly  Ser Pro Pro Arg Glu  Val Val Pro Arg Pro  Arg Pro Gly 
    1820                 1825                 1830             


Val Thr  Glu Ala Thr Ile Thr  Gly Leu Glu Pro Gly  Thr Glu Tyr 
    1835                 1840                 1845             


Thr Ile  Tyr Val Ile Ala Leu  Lys Asn Asn Gln Lys  Ser Glu Pro 
    1850                 1855                 1860             


Leu Ile  Gly Arg Lys Lys Thr  Gly Gln Glu Ala Leu  Ser Gln Thr 
    1865                 1870                 1875             


Thr Ile  Ser Trp Ala Pro Phe  Gln Asp Thr Ser Glu  Tyr Ile Ile 
    1880                 1885                 1890             


Ser Cys  His Pro Val Gly Thr  Asp Glu Glu Pro Leu  Gln Phe Arg 
    1895                 1900                 1905             


Val Pro  Gly Thr Ser Thr Ser  Ala Thr Leu Thr Gly  Leu Thr Arg 
    1910                 1915                 1920             


Gly Ala  Thr Tyr Asn Ile Ile  Val Glu Ala Leu Lys  Asp Gln Gln 
    1925                 1930                 1935             


Arg His  Lys Val Arg Glu Glu  Val Val Thr Val Gly  Asn Ser Val 
    1940                 1945                 1950             


Asn Glu  Gly Leu Asn Gln Pro  Thr Asp Asp Ser Cys  Phe Asp Pro 
    1955                 1960                 1965             


Tyr Thr  Val Ser His Tyr Ala  Val Gly Asp Glu Trp  Glu Arg Met 
    1970                 1975                 1980             


Ser Glu  Ser Gly Phe Lys Leu  Leu Cys Gln Cys Leu  Gly Phe Gly 
    1985                 1990                 1995             


Ser Gly  His Phe Arg Cys Asp  Ser Ser Arg Trp Cys  His Asp Asn 
    2000                 2005                 2010             


Gly Val  Asn Tyr Lys Ile Gly  Glu Lys Trp Asp Arg  Gln Gly Glu 
    2015                 2020                 2025             


Asn Gly  Gln Met Met Ser Cys  Thr Cys Leu Gly Asn  Gly Lys Gly 
    2030                 2035                 2040             


Glu Phe  Lys Cys Asp Pro His  Glu Ala Thr Cys Tyr  Asp Asp Gly 
    2045                 2050                 2055             


Lys Thr  Tyr His Val Gly Glu  Gln Trp Gln Lys Glu  Tyr Leu Gly 
    2060                 2065                 2070             


Ala Ile  Cys Ser Cys Thr Cys  Phe Gly Gly Gln Arg  Gly Trp Arg 
    2075                 2080                 2085             


Cys Asp  Asn Cys Arg Arg Pro  Gly Gly Glu Pro Ser  Pro Glu Gly 
    2090                 2095                 2100             


Thr Thr  Gly Gln Ser Tyr Asn  Gln Tyr Ser Gln Arg  Tyr His Gln 
    2105                 2110                 2115             


Arg Thr  Asn Thr Asn Val Asn  Cys Pro Ile Glu Cys  Phe Met Pro 
    2120                 2125                 2130             


Leu Asp  Val Gln Ala Asp Arg  Glu Asp Ser Arg Glu  
    2135                 2140                 2145 


<210>  491
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  491

Asp Arg Pro Pro Ser Pro Val Asn Val Thr Val Thr His Leu Arg Ala 
1               5                   10                  15      


Asn Ser Ala Thr Val Ser Trp Asp Val Pro Glu Gly Asn Ile Val Ile 
            20                  25                  30          


Gly Tyr Ser Ile Ser Gln Gln Arg Gln Asn Gly Pro Gly Gln Arg Val 
        35                  40                  45              


Ile Arg Glu Val Asn Thr Thr Thr Arg Ala Cys Ala Leu Trp Gly Leu 
    50                  55                  60                  


Ala Glu Asp Ser Asp Tyr Thr Val Gln Val Arg Ser Ile Gly Leu Arg 
65                  70                  75                  80  


Gly Glu Ser Pro Pro Gly Pro Arg Val His Phe Arg Thr Leu Lys Gly 
                85                  90                  95      


Ser Asp Arg Leu Pro Ser Asn Ser Ser Ser Pro Gly Asp Ile Thr Val 
            100                 105                 110         


Glu Gly Leu Asp Gly Glu Arg Pro Leu Gln Thr 
        115                 120             


<210>  492
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  492

Ala Pro Val Asn Val Thr Val Arg His Leu Lys Ala Asn Ser Ala Val 
1               5                   10                  15      


Val Ser Trp Asp Val Leu Glu Asp Glu Val Val Ile Gly Phe Ala Ile 
            20                  25                  30          


Ser Gln Gln Lys Lys Asp Val Arg Met Leu Arg Phe Ile Gln Glu Val 
        35                  40                  45              


Asn Thr Thr Thr Arg Ser Cys Ala Leu Trp Asp Leu Glu Glu Asp Thr 
    50                  55                  60                  


Glu Tyr Ile Val His Val Gln Ala Ile Ser Ile Gln Gly Gln Ser Pro 
65                  70                  75                  80  


Ala Ser Glu Pro Val Leu Phe Lys Thr Pro Arg Glu Ala Glu Lys Met 
                85                  90                  95      


Ala Ser Lys Asn Lys Asp Glu Val Thr Met Lys Glu Met Gly Arg Asn 
            100                 105                 110         


Gln Gln Leu Arg Thr 
        115         


<210>  493
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  493

Ala Pro Gly Arg Val Thr Ile Gln Glu Asp Pro Pro Gly His Leu Ser 
1               5                   10                  15      


Val Ala Trp Ser Ser Val Asp Leu Gly Asp Tyr Tyr Val Val Phe Val 
            20                  25                  30          


Lys Ser Asp Asp Gly Leu Glu Val His Cys Asn Thr Ser Leu Thr Gln 
        35                  40                  45              


Cys Asn Phe Leu Ser Glu Cys Gly Phe Thr Tyr Phe Ile Ser Val Phe 
    50                  55                  60                  


Val Tyr Asn Lys Ala Gly Gln Ser Pro Leu Gly Asp Ile Phe Asn Tyr 
65                  70                  75                  80  


Thr Thr Ala Pro Cys Cys Pro Ser Asp Ile Asn Pro Val Leu Val Ser 
                85                  90                  95      


Ser Asp Arg Val Glu Ile Val Trp Ser Pro Val Arg Gly Ala Glu Leu 
            100                 105                 110         


Tyr Glu Thr Lys Ala Val Asp Gly Tyr Asn Met Val Glu Cys Asn Asp 
        115                 120                 125             


Thr Thr Pro Ala Cys Thr Leu Ser Ala Leu Glu Cys Asp Thr Lys Tyr 
    130                 135                 140                 


Asn Ile Thr Val Tyr Ser Phe Asn Glu Val Arg Gly Ser Asn Met Ser 
145                 150                 155                 160 


Cys Thr Pro Gln Phe Ile Thr Thr Ala Pro Cys Ser Pro Glu Ile Lys 
                165                 170                 175     


Asn Val Ser Arg Asp Ala Phe Ser Met Ile Asn Val His Trp Arg Ser 
            180                 185                 190         


Thr Asn Asp Asp Ala Thr Tyr Thr Val Thr Ala Gln Gly Glu Lys Gly 
        195                 200                 205             


Leu Tyr Gln Cys Ser Ser Thr Gly Glu Ser Cys Thr Met Arg Gly Leu 
    210                 215                 220                 


Pro Cys Gly Ser Val Phe Ser Val Thr Ala Val Ala Glu Thr Gln Ala 
225                 230                 235                 240 


Gly Arg Ser Leu Pro Ser Tyr Ser Val Pro Leu Glu Thr Val Pro Cys 
                245                 250                 255     


Cys Pro Thr Gly Leu Thr Val Thr Gln Ile Thr Gln Ser Val Ile Asn 
            260                 265                 270         


Val Ser Trp Thr Ile Gly Arg Val Ala Gln Thr His Val Ala Val Leu 
        275                 280                 285             


Glu Ser His Thr Gly Gln Ser Lys Cys His Thr His Gln Asn His Cys 
    290                 295                 300                 


Leu Leu Gly Cys Ile Thr Cys Gly Ile Asn Tyr Thr Val Thr Leu Lys 
305                 310                 315                 320 


Ala Ile Ser Ala Thr Gly Leu Thr Ala Asp Cys Ser Tyr Gln Ser Tyr 
                325                 330                 335     


Phe Ser Gly Ala Cys Cys Pro Leu Gly Val Lys Leu Tyr Arg Leu Gly 
            340                 345                 350         


Pro Asn Gly Ile Arg Ile Tyr Trp Gln Ala Ser Arg Gly Ser Ala Asn 
        355                 360                 365             


Tyr Ser Thr Asp Leu Tyr Gly Ser Lys Gly Ile Phe Thr Cys Thr Pro 
    370                 375                 380                 


Ser Ala Gly Leu Ser Phe Cys Asp Val Thr Glu Ile Pro Cys Gly Asp 
385                 390                 395                 400 


Val Tyr Thr Val Met Val Ser Pro Val Ala Lys Thr Gly Leu Lys Leu 
                405                 410                 415     


Thr Phe Cys Pro Lys Lys Ile Tyr Ser Val Thr Cys Ser Gly Ser Thr 
            420                 425                 430         


Leu Gly Met Val Ile Tyr Arg Gly Lys Arg Asn Glu Glu 
        435                 440                 445 


<210>  494
<211>  715
<212>  PRT
<213>  Homo Sapiens

<400>  494

Met Val Thr Gln Glu Ser Met Leu Lys Ala Ala Leu Pro Leu Phe Thr 
1               5                   10                  15      


Arg Phe Ile Ile Ser Asn Gly Leu Arg Thr Glu His Gly Val Phe Glu 
            20                  25                  30          


Ile Thr Leu Glu Thr Val Asp Arg Ala Leu Pro Val Val Thr Arg Asn 
        35                  40                  45              


Lys Gly Leu Arg Leu Ala Gln Gly Ala Val Gly Leu Leu Ser Pro Asp 
    50                  55                  60                  


Leu Leu Gln Leu Thr Asp Pro Asp Thr Pro Ala Glu Asn Leu Thr Phe 
65                  70                  75                  80  


Leu Leu Val Gln Leu Pro Gln His Gly Gln Leu Tyr Leu Trp Gly Thr 
                85                  90                  95      


Gly Leu Leu Gln His Asn Phe Thr Gln Gln Asp Val Asp Ser Lys Asn 
            100                 105                 110         


Val Ala Tyr Arg His Ser Gly Gly Asp Ser Gln Thr Asp Cys Phe Thr 
        115                 120                 125             


Phe Met Ala Thr Asp Gly Thr Asn Gln Gly Phe Ile Val Asn Gly Arg 
    130                 135                 140                 


Val Trp Glu Glu Pro Val Leu Phe Thr Ile Gln Val Asp Gln Leu Asp 
145                 150                 155                 160 


Lys Thr Ala Pro Arg Ile Thr Leu Leu His Ser Pro Ser Gln Val Gly 
                165                 170                 175     


Leu Leu Lys Asn Gly Cys Tyr Gly Ile Tyr Ile Thr Ser Arg Val Leu 
            180                 185                 190         


Lys Ala Ser Asp Pro Asp Thr Glu Asp Asp Gln Ile Ile Phe Lys Ile 
        195                 200                 205             


Leu Gln Gly Pro Lys His Gly His Leu Glu Asn Thr Thr Thr Gly Glu 
    210                 215                 220                 


Phe Ile His Glu Lys Phe Ser Gln Lys Asp Leu Asn Ser Lys Thr Ile 
225                 230                 235                 240 


Leu Tyr Ile Ile Asn Pro Ser Leu Glu Val Asn Ser Asp Thr Val Glu 
                245                 250                 255     


Phe Gln Ile Met Asp Pro Thr Gly Asn Ser Ala Thr Pro Gln Asn Leu 
            260                 265                 270         


Glu Leu Lys Trp Ser His Ile Glu Trp Ser Gln Thr Glu Tyr Glu Val 
        275                 280                 285             


Cys Glu Asn Val Gly Leu Leu Pro Leu Glu Ile Ile Arg Arg Gly Tyr 
    290                 295                 300                 


Ser Met Asp Ser Ala Phe Val Gly Ile Lys Val Asn Gln Val Ser Ala 
305                 310                 315                 320 


Ala Val Gly Lys Asp Phe Thr Val Ile Pro Ser Lys Leu Ile Gln Phe 
                325                 330                 335     


Asp Pro Gly Met Ser Thr Lys Met Trp Asn Ile Ala Ile Thr Tyr Asp 
            340                 345                 350         


Gly Leu Glu Glu Asp Asp Glu Val Phe Glu Val Ile Leu Asn Ser Pro 
        355                 360                 365             


Val Asn Ala Val Leu Gly Thr Lys Thr Lys Ala Ala Val Lys Ile Leu 
    370                 375                 380                 


Asp Ser Lys Gly Gly Gln Cys His Pro Ser Tyr Ser Ser Asn Gln Ser 
385                 390                 395                 400 


Lys His Ser Thr Trp Glu Lys Gly Ile Trp His Leu Leu Pro Pro Gly 
                405                 410                 415     


Ser Ser Ser Ser Thr Thr Ser Gly Ser Phe His Leu Glu Arg Arg Pro 
            420                 425                 430         


Leu Pro Ser Ser Met Gln Leu Ala Val Ile Arg Gly Asp Thr Leu Arg 
        435                 440                 445             


Gly Phe Asp Ser Thr Asp Leu Ser Gln Arg Lys Leu Arg Thr Arg Gly 
    450                 455                 460                 


Asn Gly Lys Thr Val Arg Pro Ser Ser Val Tyr Arg Asn Gly Thr Asp 
465                 470                 475                 480 


Ile Ile Tyr Asn Tyr His Gly Ile Val Ser Leu Lys Leu Glu Asp Asp 
                485                 490                 495     


Ser Phe Pro Thr His Lys Arg Lys Ala Lys Val Ser Ile Ile Ser Gln 
            500                 505                 510         


Pro Gln Lys Thr Ile Lys Val Ala Glu Leu Pro Gln Ala Asp Lys Val 
        515                 520                 525             


Glu Ser Thr Thr Asp Ser His Phe Pro Arg Gln Asp Gln Leu Pro Ser 
    530                 535                 540                 


Phe Pro Lys Asn Cys Thr Leu Glu Leu Lys Gly Leu Phe His Phe Glu 
545                 550                 555                 560 


Glu Gly Ile Gln Lys Leu Tyr Gln Cys Asn Gly Ile Ala Trp Lys Ala 
                565                 570                 575     


Trp Ser Pro Gln Thr Lys Asp Val Glu Asp Lys Ser Cys Pro Ala Gly 
            580                 585                 590         


Trp His Gln His Ser Gly Tyr Cys His Ile Leu Ile Thr Glu Gln Lys 
        595                 600                 605             


Gly Thr Trp Asn Ala Ala Ala Gln Ala Cys Arg Glu Gln Tyr Leu Gly 
    610                 615                 620                 


Asn Leu Val Thr Val Phe Ser Arg Gln His Met Arg Trp Leu Trp Asp 
625                 630                 635                 640 


Ile Gly Gly Arg Lys Ser Phe Trp Ile Gly Leu Asn Asp Gln Val His 
                645                 650                 655     


Ala Gly His Trp Glu Trp Ile Gly Gly Glu Pro Val Ala Phe Thr Asn 
            660                 665                 670         


Gly Arg Arg Gly Pro Ser Pro Arg Ser Lys Leu Gly Lys Ser Cys Val 
        675                 680                 685             


Leu Val Gln Arg Gln Gly Lys Trp Gln Thr Lys Asp Cys Arg Arg Ala 
    690                 695                 700                 


Lys Pro His Asn Tyr Gly Cys Ser Arg Lys Leu 
705                 710                 715 


<210>  495
<211>  349
<212>  PRT
<213>  Homo Sapiens

<400>  495

Cys His His Arg Ile Cys His Cys Ser Asn Arg Val Phe Leu Cys Gln 
1               5                   10                  15      


Glu Ser Lys Val Thr Glu Ile Pro Ser Asp Leu Pro Arg Asn Ala Ile 
            20                  25                  30          


Glu Leu Arg Phe Val Leu Thr Lys Leu Arg Val Ile Gln Lys Gly Ala 
        35                  40                  45              


Phe Ser Gly Phe Gly Asp Leu Glu Lys Ile Glu Ile Ser Gln Asn Asp 
    50                  55                  60                  


Val Leu Glu Val Ile Glu Ala Asp Val Phe Ser Asn Leu Pro Lys Leu 
65                  70                  75                  80  


His Glu Ile Arg Ile Glu Lys Ala Asn Asn Leu Leu Tyr Ile Asn Pro 
                85                  90                  95      


Glu Ala Phe Gln Asn Leu Pro Asn Leu Gln Tyr Leu Leu Ile Ser Asn 
            100                 105                 110         


Thr Gly Ile Lys His Leu Pro Asp Val His Lys Ile His Ser Leu Gln 
        115                 120                 125             


Lys Val Leu Leu Asp Ile Gln Asp Asn Ile Asn Ile His Thr Ile Glu 
    130                 135                 140                 


Arg Asn Ser Phe Val Gly Leu Ser Phe Glu Ser Val Ile Leu Trp Leu 
145                 150                 155                 160 


Asn Lys Asn Gly Ile Gln Glu Ile His Asn Cys Ala Phe Asn Gly Thr 
                165                 170                 175     


Gln Leu Asp Glu Leu Asn Leu Ser Asp Asn Asn Asn Leu Glu Glu Leu 
            180                 185                 190         


Pro Asn Asp Val Phe His Gly Ala Ser Gly Pro Val Ile Leu Asp Ile 
        195                 200                 205             


Ser Arg Thr Arg Ile His Ser Leu Pro Ser Tyr Gly Leu Glu Asn Leu 
    210                 215                 220                 


Lys Lys Leu Arg Ala Arg Ser Thr Tyr Asn Leu Lys Lys Leu Pro Thr 
225                 230                 235                 240 


Leu Glu Lys Leu Val Ala Leu Met Glu Ala Ser Leu Thr Tyr Pro Ser 
                245                 250                 255     


His Cys Cys Ala Phe Ala Asn Trp Arg Arg Gln Ile Ser Glu Leu His 
            260                 265                 270         


Pro Ile Cys Asn Lys Ser Ile Leu Arg Gln Glu Val Asp Tyr Met Thr 
        275                 280                 285             


Gln Thr Arg Gly Gln Arg Ser Ser Leu Ala Glu Asp Asn Glu Ser Ser 
    290                 295                 300                 


Tyr Ser Arg Gly Phe Asp Met Thr Tyr Thr Glu Phe Asp Tyr Asp Leu 
305                 310                 315                 320 


Cys Asn Glu Val Val Asp Val Thr Cys Ser Pro Lys Pro Asp Ala Phe 
                325                 330                 335     


Asn Pro Cys Glu Asp Ile Met Gly Tyr Asn Ile Leu Arg 
            340                 345                 


<210>  496
<211>  583
<212>  PRT
<213>  Homo Sapiens

<400>  496

Trp Met Asp Pro Gly Thr Ser Arg Gly Pro Asp Val Gly Val Gly Glu 
1               5                   10                  15      


Ser Gln Ala Glu Glu Pro Arg Ser Phe Glu Val Thr Arg Arg Glu Gly 
            20                  25                  30          


Leu Ser Ser His Asn Glu Leu Leu Ala Ser Cys Gly Lys Lys Phe Cys 
        35                  40                  45              


Ser Arg Gly Ser Arg Cys Val Leu Ser Arg Lys Thr Gly Glu Pro Glu 
    50                  55                  60                  


Cys Gln Cys Leu Glu Ala Cys Arg Pro Ser Tyr Val Pro Val Cys Gly 
65                  70                  75                  80  


Ser Asp Gly Arg Phe Tyr Glu Asn His Cys Lys Leu His Arg Ala Ala 
                85                  90                  95      


Cys Leu Leu Gly Lys Arg Ile Thr Val Ile His Ser Lys Asp Cys Phe 
            100                 105                 110         


Leu Lys Gly Asp Thr Cys Thr Met Ala Gly Tyr Ala Arg Leu Lys Asn 
        115                 120                 125             


Val Leu Leu Ala Leu Gln Thr Arg Leu Gln Pro Leu Gln Glu Gly Asp 
    130                 135                 140                 


Ser Arg Gln Asp Pro Ala Ser Gln Lys Arg Leu Leu Val Glu Ser Leu 
145                 150                 155                 160 


Phe Arg Asp Leu Asp Ala Asp Gly Asn Gly His Leu Ser Ser Ser Glu 
                165                 170                 175     


Leu Ala Gln His Val Leu Lys Lys Gln Asp Leu Asp Glu Asp Leu Leu 
            180                 185                 190         


Gly Cys Ser Pro Gly Asp Leu Leu Arg Phe Asp Asp Tyr Asn Ser Asp 
        195                 200                 205             


Ser Ser Leu Thr Leu Arg Glu Phe Tyr Ile Ala Phe Gln Val Val Gln 
    210                 215                 220                 


Leu Ser Leu Ala Pro Glu Asp Arg Val Ser Val Thr Thr Val Thr Val 
225                 230                 235                 240 


Gly Leu Ser Thr Val Leu Thr Cys Ala Val His Gly Asp Leu Arg Pro 
                245                 250                 255     


Pro Ile Ile Trp Lys Arg Asn Gly Leu Thr Leu Asn Phe Leu Asp Leu 
            260                 265                 270         


Glu Asp Ile Asn Asp Phe Gly Glu Asp Asp Ser Leu Tyr Ile Thr Lys 
        275                 280                 285             


Val Thr Thr Ile His Met Gly Asn Tyr Thr Cys His Ala Ser Gly His 
    290                 295                 300                 


Glu Gln Leu Phe Gln Thr His Val Leu Gln Val Asn Val Pro Pro Val 
305                 310                 315                 320 


Ile Arg Val Tyr Pro Glu Ser Gln Ala Gln Glu Pro Gly Val Ala Ala 
                325                 330                 335     


Ser Leu Arg Cys His Ala Glu Gly Ile Pro Met Pro Arg Ile Thr Trp 
            340                 345                 350         


Leu Lys Asn Gly Val Asp Val Ser Thr Gln Met Ser Lys Gln Leu Ser 
        355                 360                 365             


Leu Leu Ala Asn Gly Ser Glu Leu His Ile Ser Ser Val Arg Tyr Glu 
    370                 375                 380                 


Asp Thr Gly Ala Tyr Thr Cys Ile Ala Lys Asn Glu Val Gly Val Asp 
385                 390                 395                 400 


Glu Asp Ile Ser Ser Leu Phe Ile Glu Asp Ser Ala Arg Lys Thr Leu 
                405                 410                 415     


Ala Asn Ile Leu Trp Arg Glu Glu Gly Leu Ser Val Gly Asn Met Phe 
            420                 425                 430         


Tyr Val Phe Ser Asp Asp Gly Ile Ile Val Ile His Pro Val Asp Cys 
        435                 440                 445             


Glu Ile Gln Arg His Leu Lys Pro Thr Glu Lys Ile Phe Met Ser Tyr 
    450                 455                 460                 


Glu Glu Ile Cys Pro Gln Arg Glu Lys Asn Ala Thr Gln Pro Cys Gln 
465                 470                 475                 480 


Trp Val Ser Ala Val Asn Val Arg Asn Arg Tyr Ile Tyr Val Ala Gln 
                485                 490                 495     


Pro Ala Leu Ser Arg Val Leu Val Val Asp Ile Gln Ala Gln Lys Val 
            500                 505                 510         


Leu Gln Ser Ile Gly Val Asp Pro Leu Pro Ala Lys Leu Ser Tyr Asp 
        515                 520                 525             


Lys Ser His Asp Gln Val Trp Val Leu Ser Trp Gly Asp Val His Lys 
    530                 535                 540                 


Ser Arg Pro Ser Leu Gln Val Ile Thr Glu Ala Ser Thr Gly Gln Ser 
545                 550                 555                 560 


Gln His Leu Ile Arg Thr Pro Phe Ala Gly Val Asp Asp Phe Phe Ile 
                565                 570                 575     


Pro Pro Ile Asn Leu Glu Gln 
            580             


<210>  497
<211>  827
<212>  PRT
<213>  Homo Sapiens

<400>  497

Arg Pro Thr Lys Glu Gly Gly Tyr Gly Leu Lys Ser Tyr Gln Pro Leu 
1               5                   10                  15      


Met Arg Leu Arg His Lys Gln Glu Lys Asn Gln Glu Ser Ser Arg Val 
            20                  25                  30          


Lys Gly Phe Met Ile Gln Asp Gly Pro Phe Gly Ser Cys Glu Asn Lys 
        35                  40                  45              


Tyr Cys Gly Leu Gly Arg His Cys Val Thr Ser Arg Glu Thr Gly Gln 
    50                  55                  60                  


Ala Glu Cys Ala Cys Met Asp Leu Cys Lys Arg His Tyr Lys Pro Val 
65                  70                  75                  80  


Cys Gly Ser Asp Gly Glu Phe Tyr Glu Asn His Cys Glu Val His Arg 
                85                  90                  95      


Ala Ala Cys Leu Lys Lys Gln Lys Ile Thr Ile Val His Asn Glu Asp 
            100                 105                 110         


Cys Phe Phe Lys Gly Asp Lys Cys Lys Thr Thr Glu Tyr Ser Lys Met 
        115                 120                 125             


Lys Asn Met Leu Leu Asp Leu Gln Asn Gln Lys Tyr Ile Met Gln Glu 
    130                 135                 140                 


Asn Glu Asn Pro Asn Gly Asp Asp Ile Ser Arg Lys Lys Leu Leu Val 
145                 150                 155                 160 


Asp Gln Met Phe Lys Tyr Phe Asp Ala Asp Ser Asn Gly Leu Val Asp 
                165                 170                 175     


Ile Asn Glu Leu Thr Gln Val Ile Lys Gln Glu Glu Leu Gly Lys Asp 
            180                 185                 190         


Leu Phe Asp Cys Thr Leu Tyr Val Leu Leu Lys Tyr Asp Asp Phe Asn 
        195                 200                 205             


Ala Asp Lys His Leu Ala Leu Glu Glu Phe Tyr Arg Ala Phe Gln Val 
    210                 215                 220                 


Ile Gln Leu Ser Leu Pro Glu Asp Gln Lys Leu Ser Ile Thr Ala Ala 
225                 230                 235                 240 


Thr Val Gly Gln Ser Ala Val Leu Ser Cys Ala Ile Gln Gly Thr Leu 
                245                 250                 255     


Arg Pro Pro Ile Ile Trp Lys Arg Asn Asn Ile Ile Leu Asn Asn Leu 
            260                 265                 270         


Asp Leu Glu Asp Ile Asn Asp Phe Gly Asp Asp Gly Ser Leu Tyr Ile 
        275                 280                 285             


Thr Lys Val Thr Thr Thr His Val Gly Asn Tyr Thr Cys Tyr Ala Asp 
    290                 295                 300                 


Gly Tyr Glu Gln Val Tyr Gln Thr His Ile Phe Gln Val Asn Val Pro 
305                 310                 315                 320 


Pro Val Ile Arg Val Tyr Pro Glu Ser Gln Ala Arg Glu Pro Gly Val 
                325                 330                 335     


Thr Ala Ser Leu Arg Cys His Ala Glu Gly Ile Pro Lys Pro Gln Leu 
            340                 345                 350         


Gly Trp Leu Lys Asn Gly Ile Asp Ile Thr Pro Lys Leu Ser Lys Gln 
        355                 360                 365             


Leu Thr Leu Gln Ala Asn Gly Ser Glu Val His Ile Ser Asn Val Arg 
    370                 375                 380                 


Tyr Glu Asp Thr Gly Ala Tyr Thr Cys Ile Ala Lys Asn Glu Ala Gly 
385                 390                 395                 400 


Val Asp Glu Asp Ile Ser Ser Leu Phe Val Glu Asp Ser Ala Arg Lys 
                405                 410                 415     


Thr Leu Ala Asn Ile Leu Trp Arg Glu Glu Gly Leu Gly Ile Gly Asn 
            420                 425                 430         


Met Phe Tyr Val Phe Tyr Glu Asp Gly Ile Lys Val Ile Gln Pro Ile 
        435                 440                 445             


Glu Cys Glu Phe Gln Arg His Ile Lys Pro Ser Glu Lys Leu Leu Gly 
    450                 455                 460                 


Phe Gln Asp Glu Val Cys Pro Lys Ala Glu Gly Asp Glu Val Gln Arg 
465                 470                 475                 480 


Cys Val Trp Ala Ser Ala Val Asn Val Lys Asp Lys Phe Ile Tyr Val 
                485                 490                 495     


Ala Gln Pro Thr Leu Asp Arg Val Leu Ile Val Asp Val Gln Ser Gln 
            500                 505                 510         


Lys Val Val Gln Ala Val Ser Thr Asp Pro Val Pro Val Lys Leu His 
        515                 520                 525             


Tyr Asp Lys Ser His Asp Gln Val Trp Val Leu Ser Trp Gly Thr Leu 
    530                 535                 540                 


Glu Lys Ser Ser Pro Thr Leu Gln Val Ile Thr Leu Ala Ser Gly Asn 
545                 550                 555                 560 


Val Pro His His Thr Ile His Thr Gln Pro Val Gly Lys Gln Phe Asp 
                565                 570                 575     


Arg Val Asp Asp Phe Phe Ile Pro Thr Thr Thr Leu Ile Ile Thr His 
            580                 585                 590         


Met Arg Phe Gly Phe Ile Leu His Lys Asp Glu Ala Ala Leu Gln Lys 
        595                 600                 605             


Ile Asp Ile Glu Thr Met Ser Tyr Ile Lys Thr Ile Asn Leu Lys Asp 
    610                 615                 620                 


Tyr Lys Cys Val Pro Gln Ser Leu Ala Tyr Thr His Leu Gly Gly Tyr 
625                 630                 635                 640 


Tyr Phe Ile Gly Cys Lys Pro Asp Ser Thr Gly Ala Val Ser Pro Gln 
                645                 650                 655     


Val Met Val Asp Gly Val Thr Asp Ser Val Ile Gly Phe Asn Ser Asp 
            660                 665                 670         


Val Thr Gly Thr Pro Tyr Val Ser Pro Asp Gly His Tyr Leu Val Ser 
        675                 680                 685             


Ile Asn Asp Val Lys Gly Leu Val Arg Val Gln Tyr Ile Thr Ile Arg 
    690                 695                 700                 


Gly Glu Ile Gln Glu Ala Phe Asp Ile Tyr Thr Asn Leu His Ile Ser 
705                 710                 715                 720 


Asp Leu Ala Phe Gln Pro Ser Phe Thr Glu Ala His Gln Tyr Asn Ile 
                725                 730                 735     


Tyr Gly Ser Ser Ser Thr Gln Thr Asp Val Leu Phe Val Glu Leu Ser 
            740                 745                 750         


Ser Gly Lys Val Lys Met Ile Lys Ser Leu Lys Glu Pro Leu Lys Ala 
        755                 760                 765             


Glu Glu Trp Pro Trp Asn Arg Lys Asn Arg Gln Ile Gln Asp Ser Gly 
    770                 775                 780                 


Leu Phe Gly Gln Tyr Leu Met Thr Pro Ser Lys Asp Ser Leu Phe Ile 
785                 790                 795                 800 


Leu Asp Gly Arg Leu Asn Lys Leu Asn Cys Glu Ile Thr Glu Val Glu 
                805                 810                 815     


Lys Gly Asn Thr Val Ile Trp Val Gly Asp Ala 
            820                 825         


<210>  498
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  498

Gly Trp Asp Leu Thr Val Lys Met Leu Ala Gly Asn Glu Phe Gln Val 
1               5                   10                  15      


Ser Leu Ser Ser Ser Met Ser Val Ser Glu Leu Lys Ala Gln Ile Thr 
            20                  25                  30          


Gln Lys Ile Gly Val His Ala Phe Gln Gln Arg Leu Ala Val His Pro 
        35                  40                  45              


Ser Gly Val Ala Leu Gln Asp Arg Val Pro Leu Ala Ser Gln Gly Leu 
    50                  55                  60                  


Gly Pro Gly Ser Thr Val Leu Leu Val Val Asp Lys Cys Asp Glu Pro 
65                  70                  75                  80  


Leu Ser Ile Leu Val Arg Asn Asn Lys Gly Arg Ser Ser Thr Tyr Glu 
                85                  90                  95      


Val Arg Leu Thr Gln Thr Val Ala His Leu Lys Gln Gln Val Ser Gly 
            100                 105                 110         


Leu Glu Gly Val Gln Asp Asp Leu Phe Trp Leu Thr Phe Glu Gly Lys 
        115                 120                 125             


Pro Leu Glu Asp Gln Leu Pro Leu Gly Glu Tyr Gly Leu Lys Pro Leu 
    130                 135                 140                 


Ser Thr Val Phe Met Asn Leu Arg Leu Arg Gly Gly 
145                 150                 155     


<210>  499
<211>  648
<212>  PRT
<213>  Homo Sapiens

<400>  499

Ala Leu Leu Pro Ala Arg Glu Ala Thr Gln Phe Leu Arg Pro Arg Gln 
1               5                   10                  15      


Arg Arg Ala Phe Gln Val Phe Glu Glu Ala Lys Gln Gly His Leu Glu 
            20                  25                  30          


Arg Glu Cys Val Glu Glu Leu Cys Ser Arg Glu Glu Ala Arg Glu Val 
        35                  40                  45              


Phe Glu Asn Asp Pro Glu Thr Asp Tyr Phe Tyr Pro Arg Tyr Leu Asp 
    50                  55                  60                  


Cys Ile Asn Lys Tyr Gly Ser Pro Tyr Thr Lys Asn Ser Gly Phe Ala 
65                  70                  75                  80  


Thr Cys Val Gln Asn Leu Pro Asp Gln Cys Thr Pro Asn Pro Cys Asp 
                85                  90                  95      


Arg Lys Gly Thr Gln Ala Cys Gln Asp Leu Met Gly Asn Phe Phe Cys 
            100                 105                 110         


Leu Cys Lys Ala Gly Trp Gly Gly Arg Leu Cys Asp Lys Asp Val Asn 
        115                 120                 125             


Glu Cys Ser Gln Glu Asn Gly Gly Cys Leu Gln Ile Cys His Asn Lys 
    130                 135                 140                 


Pro Gly Ser Phe His Cys Ser Cys His Ser Gly Phe Glu Leu Ser Ser 
145                 150                 155                 160 


Asp Gly Arg Thr Cys Gln Asp Ile Asp Glu Cys Ala Asp Ser Glu Ala 
                165                 170                 175     


Cys Gly Glu Ala Arg Cys Lys Asn Leu Pro Gly Ser Tyr Ser Cys Leu 
            180                 185                 190         


Cys Asp Glu Gly Phe Ala Tyr Ser Ser Gln Glu Lys Ala Cys Arg Asp 
        195                 200                 205             


Val Asp Glu Cys Leu Gln Gly Arg Cys Glu Gln Val Cys Val Asn Ser 
    210                 215                 220                 


Pro Gly Ser Tyr Thr Cys His Cys Asp Gly Arg Gly Gly Leu Lys Leu 
225                 230                 235                 240 


Ser Gln Asp Met Asp Thr Cys Glu Asp Ile Leu Pro Cys Val Pro Phe 
                245                 250                 255     


Ser Val Ala Lys Ser Val Lys Ser Leu Tyr Leu Gly Arg Met Phe Ser 
            260                 265                 270         


Gly Thr Pro Val Ile Arg Leu Arg Phe Lys Arg Leu Gln Pro Thr Arg 
        275                 280                 285             


Leu Val Ala Glu Phe Asp Phe Arg Thr Phe Asp Pro Glu Gly Ile Leu 
    290                 295                 300                 


Leu Phe Ala Gly Gly His Gln Asp Ser Thr Trp Ile Val Leu Ala Leu 
305                 310                 315                 320 


Arg Ala Gly Arg Leu Glu Leu Gln Leu Arg Tyr Asn Gly Val Gly Arg 
                325                 330                 335     


Val Thr Ser Ser Gly Pro Val Ile Asn His Gly Met Trp Gln Thr Ile 
            340                 345                 350         


Ser Val Glu Glu Leu Ala Arg Asn Leu Val Ile Lys Val Asn Arg Asp 
        355                 360                 365             


Ala Val Met Lys Ile Ala Val Ala Gly Asp Leu Phe Gln Pro Glu Arg 
    370                 375                 380                 


Gly Leu Tyr His Leu Asn Leu Thr Val Gly Gly Ile Pro Phe His Glu 
385                 390                 395                 400 


Lys Asp Leu Val Gln Pro Ile Asn Pro Arg Leu Asp Gly Cys Met Arg 
                405                 410                 415     


Ser Trp Asn Trp Leu Asn Gly Glu Asp Thr Thr Ile Gln Glu Thr Val 
            420                 425                 430         


Lys Val Asn Thr Arg Met Gln Cys Phe Ser Val Thr Glu Arg Gly Ser 
        435                 440                 445             


Phe Tyr Pro Gly Ser Gly Phe Ala Phe Tyr Ser Leu Asp Tyr Met Arg 
    450                 455                 460                 


Thr Pro Leu Asp Val Gly Thr Glu Ser Thr Trp Glu Val Glu Val Val 
465                 470                 475                 480 


Ala His Ile Arg Pro Ala Ala Asp Thr Gly Val Leu Phe Ala Leu Trp 
                485                 490                 495     


Ala Pro Asp Leu Arg Ala Val Pro Leu Ser Val Ala Leu Val Asp Tyr 
            500                 505                 510         


His Ser Thr Lys Lys Leu Lys Lys Gln Leu Val Val Leu Ala Val Glu 
        515                 520                 525             


His Thr Ala Leu Ala Leu Met Glu Ile Lys Val Cys Asp Gly Gln Glu 
    530                 535                 540                 


His Val Val Thr Val Ser Leu Arg Asp Gly Glu Ala Thr Leu Glu Val 
545                 550                 555                 560 


Asp Gly Thr Arg Gly Gln Ser Glu Val Ser Ala Ala Gln Leu Gln Glu 
                565                 570                 575     


Arg Leu Ala Val Leu Glu Arg His Leu Arg Ser Pro Val Leu Thr Phe 
            580                 585                 590         


Ala Gly Gly Leu Pro Asp Val Pro Val Thr Ser Ala Pro Val Thr Ala 
        595                 600                 605             


Phe Tyr Arg Gly Cys Met Thr Leu Glu Val Asn Arg Arg Leu Leu Asp 
    610                 615                 620                 


Leu Asp Glu Ala Ala Tyr Lys His Ser Asp Ile Thr Ala His Ser Cys 
625                 630                 635                 640 


Pro Pro Val Glu Pro Ala Ala Ala 
                645             


<210>  500
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  500

Gln Trp Asp Glu Pro Arg Val Cys Ser Arg Arg Tyr Leu Lys Val Asp 
1               5                   10                  15      


Phe Ala Asp Ile Gly Trp Asn Glu Trp Ile Ile Ser Pro Lys Ser Phe 
            20                  25                  30          


Asp Ala Tyr Tyr Cys Ala Gly Ala Cys Glu Phe Pro Met Pro Lys Ile 
        35                  40                  45              


Val Arg Pro Ser Asn His Ala Thr Ile Gln Ser Ile Val Arg Ala Val 
    50                  55                  60                  


Gly Ile Ile Pro Gly Ile Pro Glu Pro Cys Cys Val Pro Asp Lys Met 
65                  70                  75                  80  


Asn Ser Leu Gly Val Leu Phe Leu Asp Glu Asn Arg Asn Val Val Leu 
                85                  90                  95      


Lys Val Tyr Pro Asn Met Ser Val Asp Thr Cys Ala Cys Arg 
            100                 105                 110 


<210>  501
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  501

Asn Leu Gly Leu Asp Cys Asp Glu His Ser Ser Glu Ser Arg Cys Cys 
1               5                   10                  15      


Arg Tyr Pro Leu Thr Val Asp Phe Glu Ala Phe Gly Trp Asp Trp Ile 
            20                  25                  30          


Ile Ala Pro Lys Arg Tyr Lys Ala Asn Tyr Cys Ser Gly Gln Cys Glu 
        35                  40                  45              


Tyr Met Phe Met Gln Lys Tyr Pro His Thr His Leu Val Gln Gln Ala 
    50                  55                  60                  


Asn Pro Arg Gly Ser Ala Gly Pro Cys Cys Thr Pro Thr Lys Met Ser 
65                  70                  75                  80  


Pro Ile Asn Met Leu Tyr Phe Asn Asp Lys Gln Gln Ile Ile Tyr Gly 
                85                  90                  95      


Lys Ile Pro Gly Met Val Val Asp Arg Cys Gly Cys Ser 
            100                 105                 


<210>  502
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  502

Ala Arg Ala Arg Asn Gly Asp His Cys Pro Leu Gly Pro Gly Arg Cys 
1               5                   10                  15      


Cys Arg Leu His Thr Val Arg Ala Ser Leu Glu Asp Leu Gly Trp Ala 
            20                  25                  30          


Asp Trp Val Leu Ser Pro Arg Glu Val Gln Val Thr Met Cys Ile Gly 
        35                  40                  45              


Ala Cys Pro Ser Gln Phe Arg Ala Ala Asn Met His Ala Gln Ile Lys 
    50                  55                  60                  


Thr Ser Leu His Arg Leu Lys Pro Asp Thr Val Pro Ala Pro Cys Cys 
65                  70                  75                  80  


Val Pro Ala Ser Tyr Asn Pro Met Val Leu Ile Gln Lys Thr Asp Thr 
                85                  90                  95      


Gly Val Ser Leu Gln Thr Tyr Asp Asp Leu Leu Ala Lys Asp Cys His 
            100                 105                 110         


Cys Ile 
        


<210>  503
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  503

Ser Ala Gly Ala Gly Ser His Cys Gln Lys Thr Ser Leu Arg Val Asn 
1               5                   10                  15      


Phe Glu Asp Ile Gly Trp Asp Ser Trp Ile Ile Ala Pro Lys Glu Tyr 
            20                  25                  30          


Glu Ala Tyr Glu Cys Lys Gly Gly Cys Phe Phe Pro Leu Ala Asp Asp 
        35                  40                  45              


Val Thr Pro Thr Lys His Ala Ile Val Gln Thr Leu Val His Leu Lys 
    50                  55                  60                  


Phe Pro Thr Lys Val Gly Lys Ala Cys Cys Val Pro Thr Lys Leu Ser 
65                  70                  75                  80  


Pro Ile Ser Val Leu Tyr Lys Asp Asp Met Gly Val Pro Thr Leu Lys 
                85                  90                  95      


Tyr His Tyr Glu Gly Met Ser Val Ala Glu Cys Gly Cys Arg 
            100                 105                 110 


<210>  504
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  504

Ala Ala Ile Pro Val Pro Lys Leu Ser Cys Lys Asn Leu Cys His Arg 
1               5                   10                  15      


His Gln Leu Phe Ile Asn Phe Arg Asp Leu Gly Trp His Lys Trp Ile 
            20                  25                  30          


Ile Ala Pro Lys Gly Phe Met Ala Asn Tyr Cys His Gly Glu Cys Pro 
        35                  40                  45              


Phe Ser Leu Thr Ile Ser Leu Asn Ser Ser Asn Tyr Ala Phe Met Gln 
    50                  55                  60                  


Ala Leu Met His Ala Val Asp Pro Glu Ile Pro Gln Ala Val Cys Ile 
65                  70                  75                  80  


Pro Thr Lys Leu Ser Pro Ile Ser Met Leu Tyr Gln Asp Asn Asn Asp 
                85                  90                  95      


Asn Val Ile Leu Arg His Tyr Glu Asp Met Val Val Asp Glu Cys Gly 
            100                 105                 110         


Cys Gly 
        


<210>  505
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  505

Ala Pro Leu Ala Thr Arg Gln Gly Lys Arg Pro Ser Lys Asn Leu Lys 
1               5                   10                  15      


Ala Arg Cys Ser Arg Lys Ala Leu His Val Asn Phe Lys Asp Met Gly 
            20                  25                  30          


Trp Asp Asp Trp Ile Ile Ala Pro Leu Glu Tyr Glu Ala Phe His Cys 
        35                  40                  45              


Glu Gly Leu Cys Glu Phe Pro Leu Arg Ser His Leu Glu Pro Thr Asn 
    50                  55                  60                  


His Ala Val Ile Gln Thr Leu Met Asn Ser Met Asp Pro Glu Ser Thr 
65                  70                  75                  80  


Pro Pro Thr Cys Cys Val Pro Thr Arg Leu Ser Pro Ile Ser Ile Leu 
                85                  90                  95      


Phe Ile Asp Ser Ala Asn Asn Val Val Tyr Lys Gln Tyr Glu Asp Met 
            100                 105                 110         


Val Val Glu Ser Cys Gly Cys Arg 
        115                 120 


<210>  506
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  506

Thr Ala Phe Ala Ser Arg His Gly Lys Arg His Gly Lys Lys Ser Arg 
1               5                   10                  15      


Leu Arg Cys Ser Lys Lys Pro Leu His Val Asn Phe Lys Glu Leu Gly 
            20                  25                  30          


Trp Asp Asp Trp Ile Ile Ala Pro Leu Glu Tyr Glu Ala Tyr His Cys 
        35                  40                  45              


Glu Gly Val Cys Asp Phe Pro Leu Arg Ser His Leu Glu Pro Thr Asn 
    50                  55                  60                  


His Ala Ile Ile Gln Thr Leu Met Asn Ser Met Asp Pro Gly Ser Thr 
65                  70                  75                  80  


Pro Pro Ser Cys Cys Val Pro Thr Lys Leu Thr Pro Ile Ser Ile Leu 
                85                  90                  95      


Tyr Ile Asp Ala Gly Asn Asn Val Val Tyr Lys Gln Tyr Glu Asp Met 
            100                 105                 110         


Val Val Glu Ser Cys Gly Cys Arg 
        115                 120 


<210>  507
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  507

Asp Phe Gly Leu Asp Cys Asp Glu His Ser Thr Glu Ser Arg Cys Cys 
1               5                   10                  15      


Arg Tyr Pro Leu Thr Val Asp Phe Glu Ala Phe Gly Trp Asp Trp Ile 
            20                  25                  30          


Ile Ala Pro Lys Arg Tyr Lys Ala Asn Tyr Cys Ser Gly Glu Cys Glu 
        35                  40                  45              


Phe Val Phe Leu Gln Lys Tyr Pro His Thr His Leu Val His Gln Ala 
    50                  55                  60                  


Asn Pro Arg Gly Ser Ala Gly Pro Cys Cys Thr Pro Thr Lys Met Ser 
65                  70                  75                  80  


Pro Ile Asn Met Leu Tyr Phe Asn Gly Lys Glu Gln Ile Ile Tyr Gly 
                85                  90                  95      


Lys Ile Pro Ala Met Val Val Asp Arg Cys Gly Cys Ser 
            100                 105                 


<210>  508
<211>  135
<212>  PRT
<213>  Homo Sapiens

<400>  508

Gly Gln Glu Thr Val Ser Ser Glu Leu Lys Lys Pro Leu Gly Pro Ala 
1               5                   10                  15      


Ser Phe Asn Leu Ser Glu Tyr Phe Arg Gln Phe Leu Leu Pro Gln Asn 
            20                  25                  30          


Glu Cys Glu Leu His Asp Phe Arg Leu Ser Phe Ser Gln Leu Lys Trp 
        35                  40                  45              


Asp Asn Trp Ile Val Ala Pro His Arg Tyr Asn Pro Arg Tyr Cys Lys 
    50                  55                  60                  


Gly Asp Cys Pro Arg Ala Val Gly His Arg Tyr Gly Ser Pro Val His 
65                  70                  75                  80  


Thr Met Val Gln Asn Ile Ile Tyr Glu Lys Leu Asp Ser Ser Val Pro 
                85                  90                  95      


Arg Pro Ser Cys Val Pro Ala Lys Tyr Ser Pro Leu Ser Val Leu Thr 
            100                 105                 110         


Ile Glu Pro Asp Gly Ser Ile Ala Tyr Lys Glu Tyr Glu Asp Met Ile 
        115                 120                 125             


Ala Thr Lys Cys Thr Cys Arg 
    130                 135 


<210>  509
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  509

Ser Pro Asp Lys Gln Met Ala Val Leu Pro Arg Arg Glu Arg Asn Arg 
1               5                   10                  15      


Gln Ala Ala Ala Ala Asn Pro Glu Asn Ser Arg Gly Lys Gly Arg Arg 
            20                  25                  30          


Gly Gln Arg Gly Lys Asn Arg Gly Cys Val Leu Thr Ala Ile His Leu 
        35                  40                  45              


Asn Val Thr Asp Leu Gly Leu Gly Tyr Glu Thr Lys Glu Glu Leu Ile 
    50                  55                  60                  


Phe Arg Tyr Cys Ser Gly Ser Cys Asp Ala Ala Glu Thr Thr Tyr Asp 
65                  70                  75                  80  


Lys Ile Leu Lys Asn Leu Ser Arg Asn Arg Arg Leu Val Ser Asp Lys 
                85                  90                  95      


Val Gly Gln Ala Cys Cys Arg Pro Ile Ala Phe Asp Asp Asp Leu Ser 
            100                 105                 110         


Phe Leu Asp Asp Asn Leu Val Tyr His Ile Leu Arg Lys His Ser Ala 
        115                 120                 125             


Lys Arg Cys Gly Cys Ile 
    130                 


<210>  510
<211>  400
<212>  PRT
<213>  Homo Sapiens

<400>  510

Asp Arg Leu Asp Cys Val Lys Ala Ser Asp Gln Cys Leu Lys Glu Gln 
1               5                   10                  15      


Ser Cys Ser Thr Lys Tyr Arg Thr Leu Arg Gln Cys Val Ala Gly Lys 
            20                  25                  30          


Glu Thr Asn Phe Ser Leu Ala Ser Gly Leu Glu Ala Lys Asp Glu Cys 
        35                  40                  45              


Arg Ser Ala Met Glu Ala Leu Lys Gln Lys Ser Leu Tyr Asn Cys Arg 
    50                  55                  60                  


Cys Lys Arg Gly Met Lys Lys Glu Lys Asn Cys Leu Arg Ile Tyr Trp 
65                  70                  75                  80  


Ser Met Tyr Gln Ser Leu Gln Gly Asn Asp Leu Leu Glu Asp Ser Pro 
                85                  90                  95      


Tyr Glu Pro Val Asn Ser Arg Leu Ser Asp Ile Phe Arg Val Val Pro 
            100                 105                 110         


Phe Ile Ser Val Glu His Ile Pro Lys Gly Asn Asn Cys Leu Asp Ala 
        115                 120                 125             


Ala Lys Ala Cys Asn Leu Asp Asp Ile Cys Lys Lys Tyr Arg Ser Ala 
    130                 135                 140                 


Tyr Ile Thr Pro Cys Thr Thr Ser Val Ser Asn Asp Val Cys Asn Arg 
145                 150                 155                 160 


Arg Lys Cys His Lys Ala Leu Arg Gln Phe Phe Asp Lys Val Pro Ala 
                165                 170                 175     


Lys His Ser Tyr Gly Met Leu Phe Cys Ser Cys Arg Asp Ile Ala Cys 
            180                 185                 190         


Thr Glu Arg Arg Arg Gln Thr Ile Val Pro Val Cys Ser Tyr Glu Glu 
        195                 200                 205             


Arg Glu Lys Pro Asn Cys Leu Asn Leu Gln Asp Ser Cys Lys Thr Asn 
    210                 215                 220                 


Tyr Ile Cys Arg Ser Arg Leu Ala Asp Phe Phe Thr Asn Cys Gln Pro 
225                 230                 235                 240 


Glu Ser Arg Ser Val Ser Ser Cys Leu Lys Glu Asn Tyr Ala Asp Cys 
                245                 250                 255     


Leu Leu Ala Tyr Ser Gly Leu Ile Gly Thr Val Met Thr Pro Asn Tyr 
            260                 265                 270         


Ile Asp Ser Ser Ser Leu Ser Val Ala Pro Trp Cys Asp Cys Ser Asn 
        275                 280                 285             


Ser Gly Asn Asp Leu Glu Glu Cys Leu Lys Phe Leu Asn Phe Phe Lys 
    290                 295                 300                 


Asp Asn Thr Cys Leu Lys Asn Ala Ile Gln Ala Phe Gly Asn Gly Ser 
305                 310                 315                 320 


Asp Val Thr Val Trp Gln Pro Ala Phe Pro Val Gln Thr Thr Thr Ala 
                325                 330                 335     


Thr Thr Thr Thr Ala Leu Arg Val Lys Asn Lys Pro Leu Gly Pro Ala 
            340                 345                 350         


Gly Ser Glu Asn Glu Ile Pro Thr His Val Leu Pro Pro Cys Ala Asn 
        355                 360                 365             


Leu Gln Ala Gln Lys Leu Lys Ser Asn Val Ser Gly Asn Thr His Leu 
    370                 375                 380                 


Cys Ile Ser Asn Gly Asn Tyr Glu Lys Glu Gly Leu Gly Ala Ser Ser 
385                 390                 395                 400 


<210>  511
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  511

Ser Pro Ser Ser Leu Gln Gly Pro Glu Leu His Gly Trp Arg Pro Pro 
1               5                   10                  15      


Val Asp Cys Val Arg Ala Asn Glu Leu Cys Ala Ala Glu Ser Asn Cys 
            20                  25                  30          


Ser Ser Arg Tyr Arg Thr Leu Arg Gln Cys Leu Ala Gly Arg Asp Arg 
        35                  40                  45              


Asn Thr Met Leu Ala Asn Lys Glu Cys Gln Ala Ala Leu Glu Val Leu 
    50                  55                  60                  


Gln Glu Ser Pro Leu Tyr Asp Cys Arg Cys Lys Arg Gly Met Lys Lys 
65                  70                  75                  80  


Glu Leu Gln Cys Leu Gln Ile Tyr Trp Ser Ile His Leu Gly Leu Thr 
                85                  90                  95      


Glu Gly Glu Glu Phe Tyr Glu Ala Ser Pro Tyr Glu Pro Val Thr Ser 
            100                 105                 110         


Arg Leu Ser Asp Ile Phe Arg Leu Ala Ser Ile Phe Ser Gly Thr Gly 
        115                 120                 125             


Ala Asp Pro Val Val Ser Ala Lys Ser Asn His Cys Leu Asp Ala Ala 
    130                 135                 140                 


Lys Ala Cys Asn Leu Asn Asp Asn Cys Lys Lys Leu Arg Ser Ser Tyr 
145                 150                 155                 160 


Ile Ser Ile Cys Asn Arg Glu Ile Ser Pro Thr Glu Arg Cys Asn Arg 
                165                 170                 175     


Arg Lys Cys His Lys Ala Leu Arg Gln Phe Phe Asp Arg Val Pro Ser 
            180                 185                 190         


Glu Tyr Thr Tyr Arg Met Leu Phe Cys Ser Cys Gln Asp Gln Ala Cys 
        195                 200                 205             


Ala Glu Arg Arg Arg Gln Thr Ile Leu Pro Ser Cys Ser Tyr Glu Asp 
    210                 215                 220                 


Lys Glu Lys Pro Asn Cys Leu Asp Leu Arg Gly Val Cys Arg Thr Asp 
225                 230                 235                 240 


His Leu Cys Arg Ser Arg Leu Ala Asp Phe His Ala Asn Cys Arg Ala 
                245                 250                 255     


Ser Tyr Gln Thr Val Thr Ser Cys Pro Ala Asp Asn Tyr Gln Ala Cys 
            260                 265                 270         


Leu Gly Ser Tyr Ala Gly Met Ile Gly Phe Asp Met Thr Pro Asn Tyr 
        275                 280                 285             


Val Asp Ser Ser Pro Thr Gly Ile Val Val Ser Pro Trp Cys Ser Cys 
    290                 295                 300                 


Arg Gly Ser Gly Asn Met Glu Glu Glu Cys Glu Lys Phe Leu Arg Asp 
305                 310                 315                 320 


Phe Thr Glu Asn Pro Cys Leu Arg Asn Ala Ile Gln Ala Phe Gly Asn 
                325                 330                 335     


Gly Thr Asp Val Asn Val Ser Pro Lys Gly Pro Ser Phe Gln Ala Thr 
            340                 345                 350         


Gln Ala Pro Arg Val Glu Lys Thr Pro Ser Leu Pro Asp Asp Leu Ser 
        355                 360                 365             


Asp Ser Thr Ser Leu Gly Thr Ser Val Ile Thr Thr Cys Thr Ser Val 
    370                 375                 380                 


Gln Glu Gln Gly Leu Lys Ala Asn Asn Ser Lys Glu Leu Ser Met Cys 
385                 390                 395                 400 


Phe Thr Glu Leu Thr Thr Asn Ile Ile Pro Gly Ser Asn Lys Val Ile 
                405                 410                 415     


Lys Pro Asn Ser Gly Pro Ser 
            420             


<210>  512
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  512

Asp Pro Leu Pro Thr Glu Ser Arg Leu Met Asn Ser Cys Leu Gln Ala 
1               5                   10                  15      


Arg Arg Lys Cys Gln Ala Asp Pro Thr Cys Ser Ala Ala Tyr His His 
            20                  25                  30          


Leu Asp Ser Cys Thr Ser Ser Ile Ser Thr Pro Leu Pro Ser Glu Glu 
        35                  40                  45              


Pro Ser Val Pro Ala Asp Cys Leu Glu Ala Ala Gln Gln Leu Arg Asn 
    50                  55                  60                  


Ser Ser Leu Ile Gly Cys Met Cys His Arg Arg Met Lys Asn Gln Val 
65                  70                  75                  80  


Ala Cys Leu Asp Ile Tyr Trp Thr Val His Arg Ala Arg Ser Leu Gly 
                85                  90                  95      


Asn Tyr Glu Leu Asp Val Ser Pro Tyr Glu Asp Thr Val Thr Ser Lys 
            100                 105                 110         


Pro Trp Lys Met Asn Leu Ser Lys Leu Asn Met Leu Lys Pro Asp Ser 
        115                 120                 125             


Asp Leu Cys Leu Lys Phe Ala Met Leu Cys Thr Leu Asn Asp Lys Cys 
    130                 135                 140                 


Asp Arg Leu Arg Lys Ala Tyr Gly Glu Ala Cys Ser Gly Pro His Cys 
145                 150                 155                 160 


Gln Arg His Val Cys Leu Arg Gln Leu Leu Thr Phe Phe Glu Lys Ala 
                165                 170                 175     


Ala Glu Pro His Ala Gln Gly Leu Leu Leu Cys Pro Cys Ala Pro Asn 
            180                 185                 190         


Asp Arg Gly Cys Gly Glu Arg Arg Arg Asn Thr Ile Ala Pro Asn Cys 
        195                 200                 205             


Ala Leu Pro Pro Val Ala Pro Asn Cys Leu Glu Leu Arg Arg Leu Cys 
    210                 215                 220                 


Phe Ser Asp Pro Leu Cys Arg Ser Arg Leu Val Asp Phe Gln Thr His 
225                 230                 235                 240 


Cys His Pro Met Asp Ile Leu Gly Thr Cys Ala Thr Glu Gln Ser Arg 
                245                 250                 255     


Cys Leu Arg Ala Tyr Leu Gly Leu Ile Gly Thr Ala Met Thr Pro Asn 
            260                 265                 270         


Phe Val Ser Asn Val Asn Thr Ser Val Ala Leu Ser Cys Thr Cys Arg 
        275                 280                 285             


Gly Ser Gly Asn Leu Gln Glu Glu Cys Glu Met Leu Glu Gly Phe Phe 
    290                 295                 300                 


Ser His Asn Pro Cys Leu Thr Glu Ala Ile Ala Ala Lys Met Arg Phe 
305                 310                 315                 320 


His Ser Gln Leu Phe Ser Gln Asp Trp Pro His Pro Thr Phe Ala Val 
                325                 330                 335     


Met Ala His Gln Asn Glu Asn 
            340             


<210>  513
<211>  258
<212>  PRT
<213>  Homo Sapiens

<400>  513

Val Gly Gly Asn Arg Cys Val Asp Ala Ala Glu Ala Cys Thr Ala Asp 
1               5                   10                  15      


Ala Arg Cys Gln Arg Leu Arg Ser Glu Tyr Val Ala Gln Cys Leu Gly 
            20                  25                  30          


Arg Ala Ala Gln Gly Gly Cys Pro Arg Ala Arg Cys Arg Arg Ala Leu 
        35                  40                  45              


Arg Arg Phe Phe Ala Arg Gly Pro Pro Ala Leu Thr His Ala Leu Leu 
    50                  55                  60                  


Phe Cys Pro Cys Ala Gly Pro Ala Cys Ala Glu Arg Arg Arg Gln Thr 
65                  70                  75                  80  


Phe Val Pro Ser Cys Ala Phe Ser Gly Pro Gly Pro Ala Pro Pro Ser 
                85                  90                  95      


Cys Leu Glu Pro Leu Asn Phe Cys Glu Arg Ser Arg Val Cys Arg Cys 
            100                 105                 110         


Ala Arg Ala Ala Ala Gly Pro Trp Arg Gly Trp Gly Arg Gly Leu Ser 
        115                 120                 125             


Pro Ala His Arg Pro Pro Ala Ala Gln Ala Ser Pro Pro Gly Leu Ser 
    130                 135                 140                 


Gly Leu Val His Pro Ser Ala Gln Arg Pro Arg Arg Leu Pro Ala Gly 
145                 150                 155                 160 


Pro Gly Arg Pro Leu Pro Ala Arg Leu Arg Gly Pro Arg Gly Val Pro 
                165                 170                 175     


Ala Gly Thr Ala Val Thr Pro Asn Tyr Val Asp Asn Val Ser Ala Arg 
            180                 185                 190         


Val Ala Pro Trp Cys Asp Cys Gly Ala Ser Gly Asn Arg Arg Glu Asp 
        195                 200                 205             


Cys Glu Ala Phe Arg Gly Leu Phe Thr Arg Asn Arg Cys Leu Asp Gly 
    210                 215                 220                 


Ala Ile Gln Ala Phe Ala Ser Gly Trp Pro Pro Val Leu Leu Asp Gln 
225                 230                 235                 240 


Leu Asn Pro Gln Gly Asp Pro Glu His Ser Leu Leu Gln Val Ser Ser 
                245                 250                 255     


Thr Gly 
        


<210>  514
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  514

Phe Ser Gly Ser Glu Ala Thr Ala Ala Ile Leu Ser Arg Ala Pro Trp 
1               5                   10                  15      


Ser Leu Gln Ser Val Asn Pro Gly Leu Lys Thr Asn Ser Ser Lys Glu 
            20                  25                  30          


Pro Lys Phe Thr Lys Cys Arg Ser Pro Glu Arg Glu Thr Phe Ser Cys 
        35                  40                  45              


His Trp Thr Asp Glu Val His His Gly Thr Lys Asn Leu Gly Pro Ile 
    50                  55                  60                  


Gln Leu Phe Tyr Thr Arg Arg Asn Thr Gln Glu Trp Thr Gln Glu Trp 
65                  70                  75                  80  


Lys Glu Cys Pro Asp Tyr Val Ser Ala Gly Glu Asn Ser Cys Tyr Phe 
                85                  90                  95      


Asn Ser Ser Phe Thr Ser Ile Trp Ile Pro Tyr Cys Ile Lys Leu Thr 
            100                 105                 110         


Ser Asn Gly Gly Thr Val Asp Glu Lys Cys Phe Ser Val Asp Glu Ile 
        115                 120                 125             


Val Gln Pro Asp Pro Pro Ile Ala Leu Asn Trp Thr Leu Leu Asn Val 
    130                 135                 140                 


Ser Leu Thr Gly Ile His Ala Asp Ile Gln Val Arg Trp Glu Ala Pro 
145                 150                 155                 160 


Arg Asn Ala Asp Ile Gln Lys Gly Trp Met Val Leu Glu Tyr Glu Leu 
                165                 170                 175     


Gln Tyr Lys Glu Val Asn Glu Thr Lys Trp Lys Met Met Asp Pro Ile 
            180                 185                 190         


Leu Thr Thr Ser Val Pro Val Tyr Ser Leu Lys Val Asp Lys Glu Tyr 
        195                 200                 205             


Glu Val Arg Val Arg Ser Lys Gln Arg Asn Ser Gly Asn Tyr Gly Glu 
    210                 215                 220                 


Phe Ser Glu Val Leu Tyr Val Thr Leu Pro Gln Met Ser Gln Phe Thr 
225                 230                 235                 240 


Cys Glu Glu Asp Phe Tyr 
                245     


<210>  515
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  515

Gln Arg Pro Thr Gly Gly Pro Gly Cys Gly Pro Gly Arg Leu Leu Leu 
1               5                   10                  15      


Gly Thr Gly Thr Asp Ala Arg Cys Cys Arg Val His Thr Thr Arg Cys 
            20                  25                  30          


Cys Arg Asp Tyr Pro Gly Glu Glu Cys Cys Ser Glu Trp Asp Cys Met 
        35                  40                  45              


Cys Val Gln Pro Glu Phe His Cys Gly Asp Pro Cys Cys Thr Thr Cys 
    50                  55                  60                  


Arg His His Pro Cys Pro Pro Gly Gln Gly Val Gln Ser Gln Gly Lys 
65                  70                  75                  80  


Phe Ser Phe Gly Phe Gln Cys Ile Asp Cys Ala Ser Gly Thr Phe Ser 
                85                  90                  95      


Gly Gly His Glu Gly His Cys Lys Pro Trp Thr Asp Cys Thr Gln Phe 
            100                 105                 110         


Gly Phe Leu Thr Val Phe Pro Gly Asn Lys Thr His Asn Ala Val Cys 
        115                 120                 125             


Val Pro Gly Ser Pro Pro Ala Glu Pro 
    130                 135         


<210>  516
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  516

Ser Ala Thr Met Arg Ala Gln Trp Thr Tyr Ser Leu Arg Cys His Asp 
1               5                   10                  15      


Cys Ala Val Ile Asn Asp Phe Asn Cys Pro Asn Ile Arg Val Cys Pro 
            20                  25                  30          


Tyr His Ile Arg Arg Cys Met Thr Ile Ser Ile Arg Ile Asn Ser Arg 
        35                  40                  45              


Glu Leu Leu Val Tyr Lys Asn Cys Thr Asn Asn Cys Thr Phe Val Tyr 
    50                  55                  60                  


Ala Ala Glu Gln Pro Pro Glu Ala Pro Gly Lys Ile Phe Lys Thr Asn 
65                  70                  75                  80  


Ser Phe Tyr Trp Val Cys Cys Cys Asn Ser Met Val Cys Asn Ala Gly 
                85                  90                  95      


Gly Pro Thr Asn Leu Glu Arg Asp Met Leu Pro Asp Glu Val Thr Glu 
            100                 105                 110         


Glu Glu Leu Pro 
        115     


<210>  517
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  517

Arg Leu Ser Pro Glu Tyr Tyr Asp Leu Ala Arg Ala His Leu Arg Asp 
1               5                   10                  15      


Glu Glu Lys Ser Cys Pro Cys Leu Ala Gln Glu Gly Pro Gln Gly Asp 
            20                  25                  30          


Leu Leu Thr Lys Thr Gln Glu Leu Gly Arg Asp Tyr Arg Thr Cys Leu 
        35                  40                  45              


Thr Ile Val Gln Lys Leu Lys Lys Met Val Asp Lys Pro Thr Gln Arg 
    50                  55                  60                  


Ser Val Ser Asn Ala Ala Thr Arg Val Cys Arg Thr Gly Arg Ser Arg 
65                  70                  75                  80  


Trp Arg Asp Val Cys Arg Asn Phe Met Arg Arg Tyr Gln Ser Arg Val 
                85                  90                  95      


Thr Gln Gly Leu Val Ala Gly Glu Thr Ala Gln Gln Ile Cys Glu Asp 
            100                 105                 110         


Leu Arg Leu Cys Ile Pro Ser Thr Gly Pro Leu 
        115                 120             


<210>  518
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  518

His Pro Ile Cys Glu Val Ser Lys Val Ala Ser His Leu Glu Val Asn 
1               5                   10                  15      


Cys Asp Lys Arg Asn Leu Thr Ala Leu Pro Pro Asp Leu Pro Lys Asp 
            20                  25                  30          


Thr Thr Ile Leu His Leu Ser Glu Asn Leu Leu Tyr Thr Phe Ser Leu 
        35                  40                  45              


Ala Thr Leu Met Pro Tyr Thr Arg Leu Thr Gln Leu Asn Leu Asp Arg 
    50                  55                  60                  


Cys Glu Leu Thr Lys Leu Gln Val Asp Gly Thr Leu Pro Val Leu Gly 
65                  70                  75                  80  


Thr Leu Asp Leu Ser His Asn Gln Leu Gln Ser Leu Pro Leu Leu Gly 
                85                  90                  95      


Gln Thr Leu Pro Ala Leu Thr Val Leu Asp Val Ser Phe Asn Arg Leu 
            100                 105                 110         


Thr Ser Leu Pro Leu Gly Ala Leu Arg Gly Leu Gly Glu Leu Gln Glu 
        115                 120                 125             


Leu Tyr Leu Lys Gly Asn Glu Leu Lys Thr Leu Pro Pro Gly Leu Leu 
    130                 135                 140                 


Thr Pro Thr Pro Lys Leu Glu Lys Leu Ser Leu Ala Asn Asn Asn Leu 
145                 150                 155                 160 


Thr Glu Leu Pro Ala Gly Leu Leu Asn Gly Leu Glu Asn Leu Asp Thr 
                165                 170                 175     


Leu Leu Leu Gln Glu Asn Ser Leu Tyr Thr Ile Pro Lys Gly Phe Phe 
            180                 185                 190         


Gly Ser His Leu Leu Pro Phe Ala Phe Leu His Gly Asn Pro Trp Leu 
        195                 200                 205             


Cys Asn Cys Glu Ile Leu Tyr Phe Arg Arg Trp Leu Gln Asp Asn Ala 
    210                 215                 220                 


Glu Asn Val Tyr Val Trp Lys Gln Gly Val Asp Val Lys Ala Met Thr 
225                 230                 235                 240 


Ser Asn Val Ala Ser Val Gln Cys Asp Asn Ser Asp Lys Phe Pro Val 
                245                 250                 255     


Tyr Lys Tyr Pro Gly Lys Gly Cys Pro Thr Leu Gly Asp Glu Gly Asp 
            260                 265                 270         


Thr Asp Leu Tyr Asp Tyr Tyr Pro Glu Glu Asp Thr Glu Gly Asp Lys 
        275                 280                 285             


Val Arg Ala Thr Arg Thr Val Val Lys Phe Pro Thr Lys Ala His Thr 
    290                 295                 300                 


Thr Pro Trp Gly Leu Phe Tyr Ser Trp Ser Thr Ala Ser Leu Asp Ser 
305                 310                 315                 320 


Gln Met Pro Ser Ser Leu His Pro Thr Gln Glu Ser Thr Lys Glu Gln 
                325                 330                 335     


Thr Thr Phe Pro Pro Arg Trp Thr Pro Asn Phe Thr Leu His Met Glu 
            340                 345                 350         


Ser Ile Thr Phe Ser Lys Thr Pro Lys Ser Thr Thr Glu Pro Thr Pro 
        355                 360                 365             


Ser Pro Thr Thr Ser Glu Pro Val Pro Glu Pro Ala Pro Asn Met Thr 
    370                 375                 380                 


Thr Leu Glu Pro Thr Pro Ser Pro Thr Thr Pro Glu Pro Thr Ser Glu 
385                 390                 395                 400 


Pro Ala Pro Ser Pro Thr Thr Pro Glu Pro Thr Pro Ile Pro Thr Ile 
                405                 410                 415     


Ala Thr Ser Pro Thr Ile Leu Val Ser Ala Thr Ser Leu Ile Thr Pro 
            420                 425                 430         


Lys Ser Thr Phe Leu Thr Thr Thr Lys Pro Val Ser Leu Leu Glu Ser 
        435                 440                 445             


Thr Lys Lys Thr Ile Pro Glu Leu Asp Gln Pro Pro Lys Leu Arg Gly 
    450                 455                 460                 


Val Leu Gln Gly His Leu Glu Ser Ser Arg Asn Asp Pro Phe Leu His 
465                 470                 475                 480 


Pro Asp Phe Cys Cys Leu Leu Pro Leu 
                485                 


<210>  519
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  519

Pro Ala Pro Cys Ser Cys Ala Gly Thr Leu Val Asp Cys Gly Arg Arg 
1               5                   10                  15      


Gly Leu Thr Trp Ala Ser Leu Pro Thr Ala Phe Pro Val Asp Thr Thr 
            20                  25                  30          


Glu Leu Val Leu Thr Gly Asn Asn Leu Thr Ala Leu Pro Pro Gly Leu 
        35                  40                  45              


Leu Asp Ala Leu Pro Ala Leu Arg Thr Ala His Leu Gly Ala Asn Pro 
    50                  55                  60                  


Trp Arg Cys Asp Cys Arg Leu Val Pro Leu Arg Ala Trp Leu Ala Gly 
65                  70                  75                  80  


Arg Pro Glu Arg Ala Pro Tyr Arg Asp Leu Arg Cys Val Ala Pro Pro 
                85                  90                  95      


Ala Leu Arg Gly Arg Leu Leu Pro Tyr Leu Ala Glu Asp Glu Leu Arg 
            100                 105                 110         


Ala Ala Cys Ala Pro Gly Pro Leu Cys 
        115                 120     


<210>  520
<211>  327
<212>  PRT
<213>  Homo Sapiens

<400>  520

Val Glu Asp Lys Cys Glu Lys Ala Cys Arg Pro Glu Glu Glu Cys Leu 
1               5                   10                  15      


Ala Leu Asn Ser Thr Trp Gly Cys Phe Cys Arg Gln Asp Leu Asn Ser 
            20                  25                  30          


Ser Asp Val His Ser Leu Gln Pro Gln Leu Asp Cys Gly Pro Arg Glu 
        35                  40                  45              


Ile Lys Val Lys Val Asp Lys Cys Leu Leu Gly Gly Leu Gly Leu Gly 
    50                  55                  60                  


Glu Glu Val Ile Ala Tyr Leu Arg Asp Pro Asn Cys Ser Ser Ile Leu 
65                  70                  75                  80  


Gln Thr Glu Glu Arg Asn Trp Val Ser Val Thr Ser Pro Val Gln Ala 
                85                  90                  95      


Ser Ala Cys Arg Asn Ile Leu Glu Arg Asn Gln Thr His Ala Ile Tyr 
            100                 105                 110         


Lys Asn Thr Leu Ser Leu Val Asn Asp Phe Ile Ile Arg Asp Thr Ile 
        115                 120                 125             


Leu Asn Ile Asn Phe Gln Cys Ala Tyr Pro Leu Asp Met Lys Val Ser 
    130                 135                 140                 


Leu Gln Ala Ala Leu Gln Pro Ile Val Ser Ser Leu Asn Val Ser Val 
145                 150                 155                 160 


Asp Gly Asn Gly Glu Phe Ile Val Arg Met Ala Leu Phe Gln Asp Gln 
                165                 170                 175     


Asn Tyr Thr Asn Pro Tyr Gln Gly Asp Ala Val Glu Leu Ser Val Glu 
            180                 185                 190         


Ser Val Leu Tyr Val Gly Ala Ile Leu Glu Gln Gly Asp Thr Ser Arg 
        195                 200                 205             


Phe Asn Leu Val Leu Arg Asn Cys Tyr Ala Thr Pro Thr Glu Asp Lys 
    210                 215                 220                 


Ala Asp Leu Val Lys Tyr Phe Ile Ile Arg Asn Ser Cys Ser Asn Gln 
225                 230                 235                 240 


Arg Asp Ser Thr Ile His Val Glu Glu Asn Gly Gln Ser Ser Glu Ser 
                245                 250                 255     


Arg Phe Ser Val Gln Met Phe Met Phe Ala Gly His Tyr Asp Leu Val 
            260                 265                 270         


Phe Leu His Cys Glu Ile His Leu Cys Asp Ser Leu Asn Glu Gln Cys 
        275                 280                 285             


Gln Pro Ser Cys Ser Arg Ser Gln Val Arg Ser Glu Val Pro Ala Ile 
    290                 295                 300                 


Asp Leu Ala Arg Val Leu Asp Leu Gly Pro Ile Thr Arg Arg Gly Ala 
305                 310                 315                 320 


Gln Ser Pro Gly Val Met Asn 
                325         


<210>  521
<211>  507
<212>  PRT
<213>  Homo Sapiens

<400>  521

Gln Pro Phe Pro Cys Pro Pro Ala Cys Lys Cys Val Phe Arg Asp Ala 
1               5                   10                  15      


Ala Gln Cys Ser Gly Gly Asp Val Ala Arg Ile Ser Ala Leu Gly Leu 
            20                  25                  30          


Pro Thr Asn Leu Thr His Ile Leu Leu Phe Gly Met Gly Arg Gly Val 
        35                  40                  45              


Leu Gln Ser Gln Ser Phe Ser Gly Met Thr Val Leu Gln Arg Leu Met 
    50                  55                  60                  


Ile Ser Asp Ser His Ile Ser Ala Val Ala Pro Gly Thr Phe Ser Asp 
65                  70                  75                  80  


Leu Ile Lys Leu Lys Thr Leu Arg Leu Ser Arg Asn Lys Ile Thr His 
                85                  90                  95      


Leu Pro Gly Ala Leu Leu Asp Lys Met Val Leu Leu Glu Gln Leu Phe 
            100                 105                 110         


Leu Asp His Asn Ala Leu Arg Gly Ile Asp Gln Asn Met Phe Gln Lys 
        115                 120                 125             


Leu Val Asn Leu Gln Glu Leu Ala Leu Asn Gln Asn Gln Leu Asp Phe 
    130                 135                 140                 


Leu Pro Ala Ser Leu Phe Thr Asn Leu Glu Asn Leu Lys Leu Leu Asp 
145                 150                 155                 160 


Leu Ser Gly Asn Asn Leu Thr His Leu Pro Lys Gly Leu Leu Gly Ala 
                165                 170                 175     


Gln Ala Lys Leu Glu Arg Leu Leu Leu His Ser Asn Arg Leu Val Ser 
            180                 185                 190         


Leu Asp Ser Gly Leu Leu Asn Ser Leu Gly Ala Leu Thr Glu Leu Gln 
        195                 200                 205             


Phe His Arg Asn His Ile Arg Ser Ile Ala Pro Gly Ala Phe Asp Arg 
    210                 215                 220                 


Leu Pro Asn Leu Ser Ser Leu Thr Leu Ser Arg Asn His Leu Ala Phe 
225                 230                 235                 240 


Leu Pro Ser Ala Leu Phe Leu His Ser His Asn Leu Thr Leu Leu Thr 
                245                 250                 255     


Leu Phe Glu Asn Pro Leu Ala Glu Leu Pro Gly Val Leu Phe Gly Glu 
            260                 265                 270         


Met Gly Gly Leu Gln Glu Leu Trp Leu Asn Arg Thr Gln Leu Arg Thr 
        275                 280                 285             


Leu Pro Ala Ala Ala Phe Arg Asn Leu Ser Arg Leu Arg Tyr Leu Gly 
    290                 295                 300                 


Val Thr Leu Ser Pro Arg Leu Ser Ala Leu Pro Gln Gly Ala Phe Gln 
305                 310                 315                 320 


Gly Leu Gly Glu Leu Gln Val Leu Ala Leu His Ser Asn Gly Leu Thr 
                325                 330                 335     


Ala Leu Pro Asp Gly Leu Leu Arg Gly Leu Gly Lys Leu Arg Gln Val 
            340                 345                 350         


Ser Leu Arg Arg Asn Arg Leu Arg Ala Leu Pro Arg Ala Leu Phe Arg 
        355                 360                 365             


Asn Leu Ser Ser Leu Glu Ser Val Gln Leu Asp His Asn Gln Leu Glu 
    370                 375                 380                 


Thr Leu Pro Gly Asp Val Phe Gly Ala Leu Pro Arg Leu Thr Glu Val 
385                 390                 395                 400 


Leu Leu Gly His Asn Ser Trp Arg Cys Asp Cys Gly Leu Gly Pro Phe 
                405                 410                 415     


Leu Gly Trp Leu Arg Gln His Leu Gly Leu Val Gly Gly Glu Glu Pro 
            420                 425                 430         


Pro Arg Cys Ala Gly Pro Gly Ala His Ala Gly Leu Pro Leu Trp Ala 
        435                 440                 445             


Leu Pro Gly Gly Asp Ala Glu Cys Pro Gly Pro Arg Gly Pro Pro Pro 
    450                 455                 460                 


Arg Pro Ala Ala Asp Ser Ser Ser Glu Ala Pro Val His Pro Ala Leu 
465                 470                 475                 480 


Ala Pro Asn Ser Ser Glu Pro Trp Val Trp Ala Gln Pro Val Thr Thr 
                485                 490                 495     


Gly Lys Gly Gln Asp His Ser Pro Phe Trp Gly 
            500                 505         


<210>  522
<211>  247
<212>  PRT
<213>  Homo Sapiens

<400>  522

Gln Ser Gly Pro Leu Pro Lys Pro Ser Leu Gln Ala Leu Pro Ser Ser 
1               5                   10                  15      


Leu Val Pro Leu Glu Lys Pro Val Thr Leu Arg Cys Gln Gly Pro Pro 
            20                  25                  30          


Gly Val Asp Leu Tyr Arg Leu Glu Lys Leu Ser Ser Ser Arg Tyr Gln 
        35                  40                  45              


Asp Gln Ala Val Leu Phe Ile Pro Ala Met Lys Arg Ser Leu Ala Gly 
    50                  55                  60                  


Arg Tyr Arg Cys Ser Tyr Gln Asn Gly Ser Leu Trp Ser Leu Pro Ser 
65                  70                  75                  80  


Asp Gln Leu Glu Leu Val Ala Thr Gly Val Phe Ala Lys Pro Ser Leu 
                85                  90                  95      


Ser Ala Gln Pro Gly Pro Ala Val Ser Ser Gly Gly Asp Val Thr Leu 
            100                 105                 110         


Gln Cys Gln Thr Arg Tyr Gly Phe Asp Gln Phe Ala Leu Tyr Lys Glu 
        115                 120                 125             


Gly Asp Pro Ala Pro Tyr Lys Asn Pro Glu Arg Trp Tyr Arg Ala Ser 
    130                 135                 140                 


Phe Pro Ile Ile Thr Val Thr Ala Ala His Ser Gly Thr Tyr Arg Cys 
145                 150                 155                 160 


Tyr Ser Phe Ser Ser Arg Asp Pro Tyr Leu Trp Ser Ala Pro Ser Asp 
                165                 170                 175     


Pro Leu Glu Leu Val Val Thr Gly Thr Ser Val Thr Pro Ser Arg Leu 
            180                 185                 190         


Pro Thr Glu Pro Pro Ser Ser Val Ala Glu Phe Ser Glu Ala Thr Ala 
        195                 200                 205             


Glu Leu Thr Val Ser Phe Thr Asn Lys Val Phe Thr Thr Glu Thr Ser 
    210                 215                 220                 


Arg Ser Ile Thr Thr Ser Pro Lys Glu Ser Asp Ser Pro Ala Gly Pro 
225                 230                 235                 240 


Ala Arg Gln Tyr Tyr Thr Lys 
                245         


<210>  523
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  523

Thr Lys Asp Cys Pro Ser Pro Cys Thr Cys Arg Ala Leu Glu Thr Met 
1               5                   10                  15      


Gly Leu Trp Val Asp Cys Arg Gly His Gly Leu Thr Ala Leu Pro Ala 
            20                  25                  30          


Leu Pro Ala Arg Thr Arg His Leu Leu Leu Ala Asn Asn Ser Leu Gln 
        35                  40                  45              


Ser Val Pro Pro Gly Ala Phe Asp His Leu Pro Gln Leu Gln Thr Leu 
    50                  55                  60                  


Asp Val Thr Gln Asn Pro Trp His Cys Asp Cys Ser Leu Thr Tyr Leu 
65                  70                  75                  80  


Arg Leu Trp Leu Glu Asp Arg Thr Pro Glu Ala Leu Leu Gln Val Arg 
                85                  90                  95      


Cys Ala Ser Pro Ser Leu Ala Ala His Gly Pro Leu Gly Arg Leu Thr 
            100                 105                 110         


Gly Tyr Gln Leu Gly Ser Cys Gly Trp Gln Leu Gln Ala Ser Trp Val 
        115                 120                 125             


Arg Pro Gly 
    130     


<210>  524
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  524

Ile Ser Val Glu Thr Pro Gln Asp Val Leu Arg Ala Ser Gln Gly Lys 
1               5                   10                  15      


Ser Val Thr Leu Pro Cys Thr Tyr His Thr Ser Thr Ser Ser Arg Glu 
            20                  25                  30          


Gly Leu Ile Gln Trp Asp Lys Leu Leu Leu Thr His Thr Glu Arg Val 
        35                  40                  45              


Val Ile Trp Pro Phe Ser Asn Lys Asn Tyr Ile His Gly Glu Leu Tyr 
    50                  55                  60                  


Lys Asn Arg Val Ser Ile Ser Asn Asn Ala Glu Gln Ser Asp Ala Ser 
65                  70                  75                  80  


Ile Thr Ile Asp Gln Leu Thr Met Ala Asp Asn Gly Thr Tyr Glu Cys 
                85                  90                  95      


Ser Val Ser Leu Met Ser Asp Leu Glu Gly Asn Thr Lys Ser Arg Val 
            100                 105                 110         


Arg Leu Leu Val Leu Val Pro Pro Ser Lys Pro Glu Cys Gly Ile Glu 
        115                 120                 125             


Gly Glu Thr Ile Ile Gly Asn Asn Ile Gln Leu Thr Cys Gln Ser Lys 
    130                 135                 140                 


Glu Gly Ser Pro Thr Pro Gln Tyr Ser Trp Lys Arg Tyr Asn Ile Leu 
145                 150                 155                 160 


Asn Gln Glu Gln Pro Leu Ala Gln Pro Ala Ser Gly Gln Pro Val Ser 
                165                 170                 175     


Leu Lys Asn Ile Ser Thr Asp Thr Ser Gly Tyr Tyr Ile Cys Thr Ser 
            180                 185                 190         


Ser Asn Glu Glu Gly Thr Gln Phe Cys Asn Ile Thr Val Ala Val Arg 
        195                 200                 205             


Ser Pro Ser Met Asn Val 
    210                 


<210>  525
<211>  557
<212>  PRT
<213>  Homo Sapiens

<400>  525

Ala Ala Leu Thr Arg Asp Pro Gln Phe Gln Lys Leu Gln Gln Trp Tyr 
1               5                   10                  15      


Arg Glu His Arg Ser Glu Leu Asn Leu Arg Arg Leu Phe Asp Ala Asn 
            20                  25                  30          


Lys Asp Arg Phe Asn His Phe Ser Leu Thr Leu Asn Thr Asn His Gly 
        35                  40                  45              


His Ile Leu Val Asp Tyr Ser Lys Asn Leu Val Thr Glu Asp Val Met 
    50                  55                  60                  


Arg Met Leu Val Asp Leu Ala Lys Ser Arg Gly Val Glu Ala Ala Arg 
65                  70                  75                  80  


Glu Arg Met Phe Asn Gly Glu Lys Ile Asn Tyr Thr Glu Gly Arg Ala 
                85                  90                  95      


Val Leu His Val Ala Leu Arg Asn Arg Ser Asn Thr Pro Ile Leu Val 
            100                 105                 110         


Asp Gly Lys Asp Val Met Pro Glu Val Asn Lys Val Leu Asp Lys Met 
        115                 120                 125             


Lys Ser Phe Cys Gln Arg Val Arg Ser Gly Asp Trp Lys Gly Tyr Thr 
    130                 135                 140                 


Gly Lys Thr Ile Thr Asp Val Ile Asn Ile Gly Ile Gly Gly Ser Asp 
145                 150                 155                 160 


Leu Gly Pro Leu Met Val Thr Glu Ala Leu Lys Pro Tyr Ser Ser Gly 
                165                 170                 175     


Gly Pro Arg Val Trp Tyr Val Ser Asn Ile Asp Gly Thr His Ile Ala 
            180                 185                 190         


Lys Thr Leu Ala Gln Leu Asn Pro Glu Ser Ser Leu Phe Ile Ile Ala 
        195                 200                 205             


Ser Lys Thr Phe Thr Thr Gln Glu Thr Ile Thr Asn Ala Glu Thr Ala 
    210                 215                 220                 


Lys Glu Trp Phe Leu Gln Ala Ala Lys Asp Pro Ser Ala Val Ala Lys 
225                 230                 235                 240 


His Phe Val Ala Leu Ser Thr Asn Thr Thr Lys Val Lys Glu Phe Gly 
                245                 250                 255     


Ile Asp Pro Gln Asn Met Phe Glu Phe Trp Asp Trp Val Gly Gly Arg 
            260                 265                 270         


Tyr Ser Leu Trp Ser Ala Ile Gly Leu Ser Ile Ala Leu His Val Gly 
        275                 280                 285             


Phe Asp Asn Phe Glu Gln Leu Leu Ser Gly Ala His Trp Met Asp Gln 
    290                 295                 300                 


His Phe Arg Thr Thr Pro Leu Glu Lys Asn Ala Pro Val Leu Leu Ala 
305                 310                 315                 320 


Leu Leu Gly Ile Trp Tyr Ile Asn Cys Phe Gly Cys Glu Thr His Ala 
                325                 330                 335     


Met Leu Pro Tyr Asp Gln Tyr Leu His Arg Phe Ala Ala Tyr Phe Gln 
            340                 345                 350         


Gln Gly Asp Met Glu Ser Asn Gly Lys Tyr Ile Thr Lys Ser Gly Thr 
        355                 360                 365             


Arg Val Asp His Gln Thr Gly Pro Ile Val Trp Gly Glu Pro Gly Thr 
    370                 375                 380                 


Asn Gly Gln His Ala Phe Tyr Gln Leu Ile His Gln Gly Thr Lys Met 
385                 390                 395                 400 


Ile Pro Cys Asp Phe Leu Ile Pro Val Gln Thr Gln His Pro Ile Arg 
                405                 410                 415     


Lys Gly Leu His His Lys Ile Leu Leu Ala Asn Phe Leu Ala Gln Thr 
            420                 425                 430         


Glu Ala Leu Met Arg Gly Lys Ser Thr Glu Glu Ala Arg Lys Glu Leu 
        435                 440                 445             


Gln Ala Ala Gly Lys Ser Pro Glu Asp Leu Glu Arg Leu Leu Pro His 
    450                 455                 460                 


Lys Val Phe Glu Gly Asn Arg Pro Thr Asn Ser Ile Val Phe Thr Lys 
465                 470                 475                 480 


Leu Thr Pro Phe Met Leu Gly Ala Leu Val Ala Met Tyr Glu His Lys 
                485                 490                 495     


Ile Phe Val Gln Gly Ile Ile Trp Asp Ile Asn Ser Phe Asp Gln Trp 
            500                 505                 510         


Gly Val Glu Leu Gly Lys Gln Leu Ala Lys Lys Ile Glu Pro Glu Leu 
        515                 520                 525             


Asp Gly Ser Ala Gln Val Thr Ser His Asp Ala Ser Thr Asn Gly Leu 
    530                 535                 540                 


Ile Asn Phe Ile Lys Gln Gln Arg Glu Ala Arg Val Gln 
545                 550                 555         


<210>  526
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  526

Gln Thr Gln Gln Glu Glu Glu Glu Glu Asp Glu Asp His Gly Pro Asp 
1               5                   10                  15      


Asp Tyr Asp Glu Glu Asp Glu Asp Glu Val Glu Glu Glu Glu Thr Asn 
            20                  25                  30          


Arg Leu Pro Gly Gly Arg Ser Arg Val Leu Leu Arg Cys Tyr Thr Cys 
        35                  40                  45              


Lys Ser Leu Pro Arg Asp Glu Arg Cys Asn Leu Thr Gln Asn Cys Ser 
    50                  55                  60                  


His Gly Gln Thr Cys Thr Thr Leu Ile Ala His Gly Asn Thr Glu Ser 
65                  70                  75                  80  


Gly Leu Leu Thr Thr His Ser Thr Trp Cys Thr Asp Ser Cys Gln Pro 
                85                  90                  95      


Ile Thr Lys Thr Val Glu Gly Thr Gln Val Thr Met Thr Cys Cys Gln 
            100                 105                 110         


Ser Ser Leu Cys Asn Val Pro Pro Trp Gln Ser Ser Arg Val Gln Asp 
        115                 120                 125             


Pro Thr Gly 
    130     


<210>  527
<211>  465
<212>  PRT
<213>  Homo Sapiens

<400>  527

Ala Lys Arg Phe His Asp Val Leu Gly Asn Glu Arg Pro Ser Ala Tyr 
1               5                   10                  15      


Met Arg Glu His Asn Gln Leu Asn Gly Trp Ser Ser Asp Glu Asn Asp 
            20                  25                  30          


Trp Asn Glu Lys Leu Tyr Pro Val Trp Lys Arg Gly Asp Met Arg Trp 
        35                  40                  45              


Lys Asn Ser Trp Lys Gly Gly Arg Val Gln Ala Val Leu Thr Ser Asp 
    50                  55                  60                  


Ser Pro Ala Leu Val Gly Ser Asn Ile Thr Phe Ala Val Asn Leu Ile 
65                  70                  75                  80  


Phe Pro Arg Cys Gln Lys Glu Asp Ala Asn Gly Asn Ile Val Tyr Glu 
                85                  90                  95      


Lys Asn Cys Arg Asn Glu Ala Gly Leu Ser Ala Asp Pro Tyr Val Tyr 
            100                 105                 110         


Asn Trp Thr Ala Trp Ser Glu Asp Ser Asp Gly Glu Asn Gly Thr Gly 
        115                 120                 125             


Gln Ser His His Asn Val Phe Pro Asp Gly Lys Pro Phe Pro His His 
    130                 135                 140                 


Pro Gly Trp Arg Arg Trp Asn Phe Ile Tyr Val Phe His Thr Leu Gly 
145                 150                 155                 160 


Gln Tyr Phe Gln Lys Leu Gly Arg Cys Ser Val Arg Val Ser Val Asn 
                165                 170                 175     


Thr Ala Asn Val Thr Leu Gly Pro Gln Leu Met Glu Val Thr Val Tyr 
            180                 185                 190         


Arg Arg His Gly Arg Ala Tyr Val Pro Ile Ala Gln Val Lys Asp Val 
        195                 200                 205             


Tyr Val Val Thr Asp Gln Ile Pro Val Phe Val Thr Met Phe Gln Lys 
    210                 215                 220                 


Asn Asp Arg Asn Ser Ser Asp Glu Thr Phe Leu Lys Asp Leu Pro Ile 
225                 230                 235                 240 


Met Phe Asp Val Leu Ile His Asp Pro Ser His Phe Leu Asn Tyr Ser 
                245                 250                 255     


Thr Ile Asn Tyr Lys Trp Ser Phe Gly Asp Asn Thr Gly Leu Phe Val 
            260                 265                 270         


Ser Thr Asn His Thr Val Asn His Thr Tyr Val Leu Asn Gly Thr Phe 
        275                 280                 285             


Ser Leu Asn Leu Thr Val Lys Ala Ala Ala Pro Gly Pro Cys Pro Pro 
    290                 295                 300                 


Pro Pro Pro Pro Pro Arg Pro Ser Lys Pro Thr Pro Ser Leu Ala Thr 
305                 310                 315                 320 


Thr Leu Lys Ser Tyr Asp Ser Asn Thr Pro Gly Pro Ala Gly Asp Asn 
                325                 330                 335     


Pro Leu Glu Leu Ser Arg Ile Pro Asp Glu Asn Cys Gln Ile Asn Arg 
            340                 345                 350         


Tyr Gly His Phe Gln Ala Thr Ile Thr Ile Val Glu Gly Ile Leu Glu 
        355                 360                 365             


Val Asn Ile Ile Gln Met Thr Asp Val Leu Met Pro Val Pro Trp Pro 
    370                 375                 380                 


Glu Ser Ser Leu Ile Asp Phe Val Val Thr Cys Gln Gly Ser Ile Pro 
385                 390                 395                 400 


Thr Glu Val Cys Thr Ile Ile Ser Asp Pro Thr Cys Glu Ile Thr Gln 
                405                 410                 415     


Asn Thr Val Cys Ser Pro Val Asp Val Asp Glu Met Cys Leu Leu Thr 
            420                 425                 430         


Val Arg Arg Thr Phe Asn Gly Ser Gly Thr Tyr Cys Val Asn Leu Thr 
        435                 440                 445             


Leu Gly Asp Asp Thr Ser Leu Ala Leu Thr Ser Thr Leu Ile Ser Val 
    450                 455                 460                 


Pro 
465 


<210>  528
<211>  629
<212>  PRT
<213>  Homo Sapiens

<400>  528

Leu Gln Gly Gly Met Leu Tyr Pro Gln Glu Ser Pro Ser Arg Glu Cys 
1               5                   10                  15      


Lys Glu Leu Asp Gly Leu Trp Ser Phe Arg Ala Asp Phe Ser Asp Asn 
            20                  25                  30          


Arg Arg Arg Gly Phe Glu Glu Gln Trp Tyr Arg Arg Pro Leu Trp Glu 
        35                  40                  45              


Ser Gly Pro Thr Val Asp Met Pro Val Pro Ser Ser Phe Asn Asp Ile 
    50                  55                  60                  


Ser Gln Asp Trp Arg Leu Arg His Phe Val Gly Trp Val Trp Tyr Glu 
65                  70                  75                  80  


Arg Glu Val Ile Leu Pro Glu Arg Trp Thr Gln Asp Leu Arg Thr Arg 
                85                  90                  95      


Val Val Leu Arg Ile Gly Ser Ala His Ser Tyr Ala Ile Val Trp Val 
            100                 105                 110         


Asn Gly Val Asp Thr Leu Glu His Glu Gly Gly Tyr Leu Pro Phe Glu 
        115                 120                 125             


Ala Asp Ile Ser Asn Leu Val Gln Val Gly Pro Leu Pro Ser Arg Leu 
    130                 135                 140                 


Arg Ile Thr Ile Ala Ile Asn Asn Thr Leu Thr Pro Thr Thr Leu Pro 
145                 150                 155                 160 


Pro Gly Thr Ile Gln Tyr Leu Thr Asp Thr Ser Lys Tyr Pro Lys Gly 
                165                 170                 175     


Tyr Phe Val Gln Asn Thr Tyr Phe Asp Phe Phe Asn Tyr Ala Gly Leu 
            180                 185                 190         


Gln Arg Ser Val Leu Leu Tyr Thr Thr Pro Thr Thr Tyr Ile Asp Asp 
        195                 200                 205             


Ile Thr Val Thr Thr Ser Val Glu Gln Asp Ser Gly Leu Val Asn Tyr 
    210                 215                 220                 


Gln Ile Ser Val Lys Gly Ser Asn Leu Phe Lys Leu Glu Val Arg Leu 
225                 230                 235                 240 


Leu Asp Ala Glu Asn Lys Val Val Ala Asn Gly Thr Gly Thr Gln Gly 
                245                 250                 255     


Gln Leu Lys Val Pro Gly Val Ser Leu Trp Trp Pro Tyr Leu Met His 
            260                 265                 270         


Glu Arg Pro Ala Tyr Leu Tyr Ser Leu Glu Val Gln Leu Thr Ala Gln 
        275                 280                 285             


Thr Ser Leu Gly Pro Val Ser Asp Phe Tyr Thr Leu Pro Val Gly Ile 
    290                 295                 300                 


Arg Thr Val Ala Val Thr Lys Ser Gln Phe Leu Ile Asn Gly Lys Pro 
305                 310                 315                 320 


Phe Tyr Phe His Gly Val Asn Lys His Glu Asp Ala Asp Ile Arg Gly 
                325                 330                 335     


Lys Gly Phe Asp Trp Pro Leu Leu Val Lys Asp Phe Asn Leu Leu Arg 
            340                 345                 350         


Trp Leu Gly Ala Asn Ala Phe Arg Thr Ser His Tyr Pro Tyr Ala Glu 
        355                 360                 365             


Glu Val Met Gln Met Cys Asp Arg Tyr Gly Ile Val Val Ile Asp Glu 
    370                 375                 380                 


Cys Pro Gly Val Gly Leu Ala Leu Pro Gln Phe Phe Asn Asn Val Ser 
385                 390                 395                 400 


Leu His His His Met Gln Val Met Glu Glu Val Val Arg Arg Asp Lys 
                405                 410                 415     


Asn His Pro Ala Val Val Met Trp Ser Val Ala Asn Glu Pro Ala Ser 
            420                 425                 430         


His Leu Glu Ser Ala Gly Tyr Tyr Leu Lys Met Val Ile Ala His Thr 
        435                 440                 445             


Lys Ser Leu Asp Pro Ser Arg Pro Val Thr Phe Val Ser Asn Ser Asn 
    450                 455                 460                 


Tyr Ala Ala Asp Lys Gly Ala Pro Tyr Val Asp Val Ile Cys Leu Asn 
465                 470                 475                 480 


Ser Tyr Tyr Ser Trp Tyr His Asp Tyr Gly His Leu Glu Leu Ile Gln 
                485                 490                 495     


Leu Gln Leu Ala Thr Gln Phe Glu Asn Trp Tyr Lys Lys Tyr Gln Lys 
            500                 505                 510         


Pro Ile Ile Gln Ser Glu Tyr Gly Ala Glu Thr Ile Ala Gly Phe His 
        515                 520                 525             


Gln Asp Pro Pro Leu Met Phe Thr Glu Glu Tyr Gln Lys Ser Leu Leu 
    530                 535                 540                 


Glu Gln Tyr His Leu Gly Leu Asp Gln Lys Arg Arg Lys Tyr Val Val 
545                 550                 555                 560 


Gly Glu Leu Ile Trp Asn Phe Ala Asp Phe Met Thr Glu Gln Ser Pro 
                565                 570                 575     


Thr Arg Val Leu Gly Asn Lys Lys Gly Ile Phe Thr Arg Gln Arg Gln 
            580                 585                 590         


Pro Lys Ser Ala Ala Phe Leu Leu Arg Glu Arg Tyr Trp Lys Ile Ala 
        595                 600                 605             


Asn Glu Thr Arg Tyr Pro His Ser Val Ala Lys Ser Gln Cys Leu Glu 
    610                 615                 620                 


Asn Ser Leu Phe Thr 
625                 


<210>  529
<211>  537
<212>  PRT
<213>  Homo Sapiens

<400>  529

Phe Ser Leu Met Ser Leu Leu Glu Ser Leu Asp Pro Asp Trp Thr Pro 
1               5                   10                  15      


Asp Gln Tyr Asp Tyr Ser Tyr Glu Asp Tyr Asn Gln Glu Glu Asn Thr 
            20                  25                  30          


Ser Ser Thr Leu Thr His Ala Glu Asn Pro Asp Trp Tyr Tyr Thr Glu 
        35                  40                  45              


Asp Gln Ala Asp Pro Cys Gln Pro Asn Pro Cys Glu His Gly Gly Asp 
    50                  55                  60                  


Cys Leu Val His Gly Ser Thr Phe Thr Cys Ser Cys Leu Ala Pro Phe 
65                  70                  75                  80  


Ser Gly Asn Lys Cys Gln Lys Val Gln Asn Thr Cys Lys Asp Asn Pro 
                85                  90                  95      


Cys Gly Arg Gly Gln Cys Leu Ile Thr Gln Ser Pro Pro Tyr Tyr Arg 
            100                 105                 110         


Cys Val Cys Lys His Pro Tyr Thr Gly Pro Ser Cys Ser Gln Val Val 
        115                 120                 125             


Pro Val Cys Arg Pro Asn Pro Cys Gln Asn Gly Ala Thr Cys Ser Arg 
    130                 135                 140                 


His Lys Arg Arg Ser Lys Phe Thr Cys Ala Cys Pro Asp Gln Phe Lys 
145                 150                 155                 160 


Gly Lys Phe Cys Glu Ile Gly Ser Asp Asp Cys Tyr Val Gly Asp Gly 
                165                 170                 175     


Tyr Ser Tyr Arg Gly Lys Met Asn Arg Thr Val Asn Gln His Ala Cys 
            180                 185                 190         


Leu Tyr Trp Asn Ser His Leu Leu Leu Gln Glu Asn Tyr Asn Met Phe 
        195                 200                 205             


Met Glu Asp Ala Glu Thr His Gly Ile Gly Glu His Asn Phe Cys Arg 
    210                 215                 220                 


Asn Pro Asp Ala Asp Glu Lys Pro Trp Cys Phe Ile Lys Val Thr Asn 
225                 230                 235                 240 


Asp Lys Val Lys Trp Glu Tyr Cys Asp Val Ser Ala Cys Ser Ala Gln 
                245                 250                 255     


Asp Val Ala Tyr Pro Glu Glu Ser Pro Thr Glu Pro Ser Thr Lys Leu 
            260                 265                 270         


Pro Gly Phe Asp Ser Cys Gly Lys Thr Glu Ile Ala Glu Arg Lys Ile 
        275                 280                 285             


Lys Arg Ile Tyr Gly Gly Phe Lys Ser Thr Ala Gly Lys His Pro Trp 
    290                 295                 300                 


Gln Ala Ser Leu Gln Ser Ser Leu Pro Leu Thr Ile Ser Met Pro Gln 
305                 310                 315                 320 


Gly His Phe Cys Gly Gly Ala Leu Ile His Pro Cys Trp Val Leu Thr 
                325                 330                 335     


Ala Ala His Cys Thr Asp Ile Lys Thr Arg His Leu Lys Val Val Leu 
            340                 345                 350         


Gly Asp Gln Asp Leu Lys Lys Glu Glu Phe His Glu Gln Ser Phe Arg 
        355                 360                 365             


Val Glu Lys Ile Phe Lys Tyr Ser His Tyr Asn Glu Arg Asp Glu Ile 
    370                 375                 380                 


Pro His Asn Asp Ile Ala Leu Leu Lys Leu Lys Pro Val Asp Gly His 
385                 390                 395                 400 


Cys Ala Leu Glu Ser Lys Tyr Val Lys Thr Val Cys Leu Pro Asp Gly 
                405                 410                 415     


Ser Phe Pro Ser Gly Ser Glu Cys His Ile Ser Gly Trp Gly Val Thr 
            420                 425                 430         


Glu Thr Gly Lys Gly Ser Arg Gln Leu Leu Asp Ala Lys Val Lys Leu 
        435                 440                 445             


Ile Ala Asn Thr Leu Cys Asn Ser Arg Gln Leu Tyr Asp His Met Ile 
    450                 455                 460                 


Asp Asp Ser Met Ile Cys Ala Gly Asn Leu Gln Lys Pro Gly Gln Asp 
465                 470                 475                 480 


Thr Cys Gln Gly Asp Ser Gly Gly Pro Leu Thr Cys Glu Lys Asp Gly 
                485                 490                 495     


Thr Tyr Tyr Val Tyr Gly Ile Val Ser Trp Gly Leu Glu Cys Gly Lys 
            500                 505                 510         


Arg Pro Gly Val Tyr Thr Gln Val Thr Lys Phe Leu Asn Trp Ile Lys 
        515                 520                 525             


Ala Thr Ile Lys Ser Glu Ser Gly Phe 
    530                 535         


<210>  530
<211>  25
<212>  PRT
<213>  Homo Sapiens

<400>  530

Asp Thr His Phe Pro Ile Cys Ile Phe Cys Cys Gly Cys Cys His Arg 
1               5                   10                  15      


Ser Lys Cys Gly Met Cys Cys Lys Thr 
            20                  25  


<210>  531
<211>  339
<212>  PRT
<213>  Homo Sapiens

<400>  531

Asp His Leu Ser Asp Asn Tyr Thr Leu Asp His Asp Arg Ala Ile His 
1               5                   10                  15      


Ile Gln Ala Glu Asn Gly Pro His Leu Leu Val Glu Ala Glu Gln Ala 
            20                  25                  30          


Lys Val Phe Ser His Arg Gly Gly Asn Val Thr Leu Pro Cys Lys Phe 
        35                  40                  45              


Tyr Arg Asp Pro Thr Ala Phe Gly Ser Gly Ile His Lys Ile Arg Ile 
    50                  55                  60                  


Lys Trp Thr Lys Leu Thr Ser Asp Tyr Leu Lys Glu Val Asp Val Phe 
65                  70                  75                  80  


Val Ser Met Gly Tyr His Lys Lys Thr Tyr Gly Gly Tyr Gln Gly Arg 
                85                  90                  95      


Val Phe Leu Lys Gly Gly Ser Asp Ser Asp Ala Ser Leu Val Ile Thr 
            100                 105                 110         


Asp Leu Thr Leu Glu Asp Tyr Gly Arg Tyr Lys Cys Glu Val Ile Glu 
        115                 120                 125             


Gly Leu Glu Asp Asp Thr Val Val Val Ala Leu Asp Leu Gln Gly Val 
    130                 135                 140                 


Val Phe Pro Tyr Phe Pro Arg Leu Gly Arg Tyr Asn Leu Asn Phe His 
145                 150                 155                 160 


Glu Ala Gln Gln Ala Cys Leu Asp Gln Asp Ala Val Ile Ala Ser Phe 
                165                 170                 175     


Asp Gln Leu Tyr Asp Ala Trp Arg Gly Gly Leu Asp Trp Cys Asn Ala 
            180                 185                 190         


Gly Trp Leu Ser Asp Gly Ser Val Gln Tyr Pro Ile Thr Lys Pro Arg 
        195                 200                 205             


Glu Pro Cys Gly Gly Gln Asn Thr Val Pro Gly Val Arg Asn Tyr Gly 
    210                 215                 220                 


Phe Trp Asp Lys Asp Lys Ser Arg Tyr Asp Val Phe Cys Phe Thr Ser 
225                 230                 235                 240 


Asn Phe Asn Gly Arg Phe Tyr Tyr Leu Ile His Pro Thr Lys Leu Thr 
                245                 250                 255     


Tyr Asp Val Ala Val Gln Ala Cys Leu Asn Asp Gly Ala Gln Ile Ala 
            260                 265                 270         


Lys Val Gly Gln Ile Phe Ala Ala Trp Lys Ile Leu Gly Tyr Asp Arg 
        275                 280                 285             


Cys Asp Ala Gly Trp Leu Ala Asp Gly Ser Val Arg Tyr Pro Ile Ser 
    290                 295                 300                 


Arg Pro Arg Arg Arg Cys Ser Pro Thr Glu Ala Ala Val Arg Phe Val 
305                 310                 315                 320 


Gly Phe Pro Asp Lys Lys His Lys Leu Tyr Gly Val Tyr Cys Phe Arg 
                325                 330                 335     


Ala Tyr Asn 
            


<210>  532
<211>  314
<212>  PRT
<213>  Homo Sapiens

<400>  532

Asp Pro Ala Ser His Pro Gly Pro His Tyr Leu Leu Pro Pro Ile His 
1               5                   10                  15      


Glu Val Ile His Ser His Arg Gly Ala Thr Ala Thr Leu Pro Cys Val 
            20                  25                  30          


Leu Gly Thr Thr Pro Pro Ser Tyr Lys Val Arg Trp Ser Lys Val Glu 
        35                  40                  45              


Pro Gly Glu Leu Arg Glu Thr Leu Ile Leu Ile Thr Asn Gly Leu His 
    50                  55                  60                  


Ala Arg Gly Tyr Gly Pro Leu Gly Gly Arg Ala Arg Met Arg Arg Gly 
65                  70                  75                  80  


His Arg Leu Asp Ala Ser Leu Val Ile Ala Gly Val Arg Leu Glu Asp 
                85                  90                  95      


Glu Gly Arg Tyr Arg Cys Glu Leu Ile Asn Gly Ile Glu Asp Glu Ser 
            100                 105                 110         


Val Ala Leu Thr Leu Ser Leu Glu Gly Val Val Phe Pro Tyr Gln Pro 
        115                 120                 125             


Ser Arg Gly Arg Tyr Gln Phe Asn Tyr Tyr Glu Ala Lys Gln Ala Cys 
    130                 135                 140                 


Glu Glu Gln Asp Gly Arg Leu Ala Thr Tyr Ser Gln Leu Tyr Gln Ala 
145                 150                 155                 160 


Trp Thr Glu Gly Leu Asp Trp Cys Asn Ala Gly Trp Leu Leu Glu Gly 
                165                 170                 175     


Ser Val Arg Tyr Pro Val Leu Thr Ala Arg Ala Pro Cys Gly Gly Arg 
            180                 185                 190         


Gly Arg Pro Gly Ile Arg Ser Tyr Gly Pro Arg Asp Arg Met Arg Asp 
        195                 200                 205             


Arg Tyr Asp Ala Phe Cys Phe Thr Ser Ala Leu Ala Gly Gln Val Phe 
    210                 215                 220                 


Phe Val Pro Gly Arg Leu Thr Leu Ser Glu Ala His Ala Ala Cys Arg 
225                 230                 235                 240 


Arg Arg Gly Ala Val Val Ala Lys Val Gly His Leu Tyr Ala Ala Trp 
                245                 250                 255     


Lys Phe Ser Gly Leu Asp Gln Cys Asp Gly Gly Trp Leu Ala Asp Gly 
            260                 265                 270         


Ser Val Arg Phe Pro Ile Thr Thr Pro Arg Pro Arg Cys Gly Gly Leu 
        275                 280                 285             


Pro Asp Pro Gly Val Arg Ser Phe Gly Phe Pro Arg Pro Gln Gln Ala 
    290                 295                 300                 


Ala Tyr Gly Thr Tyr Cys Tyr Ala Glu Asn 
305                 310                 


<210>  533
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  533

Leu Pro Phe Tyr Asn Gly Phe Tyr Tyr Ser Asn Ser Ala Asn Asp Gln 
1               5                   10                  15      


Asn Leu Gly Asn Gly His Gly Lys Asp Leu Leu Asn Gly Val Lys Leu 
            20                  25                  30          


Val Val Glu Thr Pro Glu Glu Thr Leu Phe Thr Tyr Gln Gly Ala Ser 
        35                  40                  45              


Val Ile Leu Pro Cys Arg Tyr Arg Tyr Glu Pro Ala Leu Val Ser Pro 
    50                  55                  60                  


Arg Arg Val Arg Val Lys Trp Trp Lys Leu Ser Glu Asn Gly Ala Pro 
65                  70                  75                  80  


Glu Lys Asp Val Leu Val Ala Ile Gly Leu Arg His Arg Ser Phe Gly 
                85                  90                  95      


Asp Tyr Gln Gly Arg Val His Leu Arg Gln Asp Lys Glu His Asp Val 
            100                 105                 110         


Ser Leu Glu Ile Gln Asp Leu Arg Leu Glu Asp Tyr Gly Arg Tyr Arg 
        115                 120                 125             


Cys Glu Val Ile Asp Gly Leu Glu Asp Glu Ser Gly Leu Val Glu Leu 
    130                 135                 140                 


Glu Leu Arg Gly Val Val Phe Pro Tyr Gln Ser Pro Asn Gly Arg Tyr 
145                 150                 155                 160 


Gln Phe Asn Phe His Glu Gly Gln Gln Val Cys Ala Glu Gln Ala Ala 
                165                 170                 175     


Val Val Ala Ser Phe Glu Gln Leu Phe Arg Ala Trp Glu Glu Gly Leu 
            180                 185                 190         


Asp Trp Cys Asn Ala Gly Trp Leu Gln Asp Ala Thr Val Gln Tyr Pro 
        195                 200                 205             


Ile Met Leu Pro Arg Gln Pro Cys Gly Gly Pro Gly Leu Ala Pro Gly 
    210                 215                 220                 


Val Arg Ser Tyr Gly Pro Arg His Arg Arg Leu His Arg Tyr Asp Val 
225                 230                 235                 240 


Phe Cys Phe Ala Thr Ala Leu Lys Gly Arg Val Tyr Tyr Leu Glu His 
                245                 250                 255     


Pro Glu Lys Leu Thr Leu Thr Glu Ala Arg Glu Ala Cys Gln Glu Asp 
            260                 265                 270         


Asp Ala Thr Ile Ala Lys Val Gly Gln Leu Phe Ala Ala Trp Lys Phe 
        275                 280                 285             


His Gly Leu Asp Arg Cys Asp Ala Gly Trp Leu Ala Asp Gly Ser Val 
    290                 295                 300                 


Arg Tyr Pro Val Val His Pro His Pro Asn Cys Gly Pro Pro Glu Pro 
305                 310                 315                 320 


Gly Val Arg Ser Phe Gly Phe Pro Asp Pro Gln Ser Arg Leu Tyr Gly 
                325                 330                 335     


Val Tyr Cys Tyr Arg Gln His 
            340             


<210>  534
<211>  373
<212>  PRT
<213>  Homo Sapiens

<400>  534

Gln Arg Gly Arg Lys Lys Val Val His Val Leu Glu Gly Glu Ser Gly 
1               5                   10                  15      


Ser Val Val Val Gln Thr Ala Pro Gly Gln Val Val Ser His Arg Gly 
            20                  25                  30          


Gly Thr Ile Val Leu Pro Cys Arg Tyr His Tyr Glu Ala Ala Ala His 
        35                  40                  45              


Gly His Asp Gly Val Arg Leu Lys Trp Thr Lys Val Val Asp Pro Leu 
    50                  55                  60                  


Ala Phe Thr Asp Val Phe Val Ala Leu Gly Pro Gln His Arg Ala Phe 
65                  70                  75                  80  


Gly Ser Tyr Arg Gly Arg Ala Glu Leu Gln Gly Asp Gly Pro Gly Asp 
                85                  90                  95      


Ala Ser Leu Val Leu Arg Asn Val Thr Leu Gln Asp Tyr Gly Arg Tyr 
            100                 105                 110         


Glu Cys Glu Val Thr Asn Glu Leu Glu Asp Asp Ala Gly Met Val Lys 
        115                 120                 125             


Leu Asp Leu Glu Gly Val Val Phe Pro Tyr His Pro Arg Gly Gly Arg 
    130                 135                 140                 


Tyr Lys Leu Thr Phe Ala Glu Ala Gln Arg Ala Cys Ala Glu Gln Asp 
145                 150                 155                 160 


Gly Ile Leu Ala Ser Ala Glu Gln Leu His Ala Ala Trp Arg Asp Gly 
                165                 170                 175     


Leu Asp Trp Cys Asn Ala Gly Trp Leu Arg Asp Gly Ser Val Gln Tyr 
            180                 185                 190         


Pro Val Asn Arg Pro Arg Glu Pro Cys Gly Gly Leu Gly Gly Thr Gly 
        195                 200                 205             


Ser Ala Gly Gly Gly Gly Asp Ala Asn Gly Gly Leu Arg Asn Tyr Gly 
    210                 215                 220                 


Tyr Arg His Asn Ala Glu Glu Arg Tyr Asp Ala Phe Cys Phe Thr Ser 
225                 230                 235                 240 


Asn Leu Pro Gly Arg Val Phe Phe Leu Lys Pro Leu Arg Pro Val Pro 
                245                 250                 255     


Phe Ser Gly Ala Ala Arg Ala Cys Ala Ala Arg Gly Ala Ala Val Ala 
            260                 265                 270         


Lys Val Gly Gln Leu Phe Ala Ala Trp Lys Leu Gln Leu Leu Asp Arg 
        275                 280                 285             


Cys Thr Ala Gly Trp Leu Ala Asp Gly Ser Ala Arg Tyr Pro Ile Val 
    290                 295                 300                 


Asn Pro Arg Ala Arg Cys Gly Gly Arg Arg Pro Gly Val Arg Ser Leu 
305                 310                 315                 320 


Gly Phe Pro Asp Ala Thr Arg Arg Leu Phe Gly Val Tyr Cys Tyr Arg 
                325                 330                 335     


Ala Pro Gly Ala Pro Asp Pro Ala Pro Gly Gly Trp Gly Trp Gly Trp 
            340                 345                 350         


Ala Gly Gly Gly Gly Trp Ala Gly Gly Ala Arg Asp Pro Ala Ala Trp 
        355                 360                 365             


Thr Pro Leu His Val 
    370             


<210>  535
<211>  275
<212>  PRT
<213>  Homo Sapiens

<400>  535

Ser Val Lys Val Gly Gly Glu Ala Gly Pro Ser Val Thr Leu Pro Cys 
1               5                   10                  15      


His Tyr Ser Gly Ala Val Thr Ser Met Cys Trp Asn Arg Gly Ser Cys 
            20                  25                  30          


Ser Leu Phe Thr Cys Gln Asn Gly Ile Val Trp Thr Asn Gly Thr His 
        35                  40                  45              


Val Thr Tyr Arg Lys Asp Thr Arg Tyr Lys Leu Leu Gly Asp Leu Ser 
    50                  55                  60                  


Arg Arg Asp Val Ser Leu Thr Ile Glu Asn Thr Ala Val Ser Asp Ser 
65                  70                  75                  80  


Gly Val Tyr Cys Cys Arg Val Glu His Arg Gly Trp Phe Asn Asp Met 
                85                  90                  95      


Lys Ile Thr Val Ser Leu Glu Ile Val Pro Pro Lys Val Thr Thr Thr 
            100                 105                 110         


Pro Ile Val Thr Thr Val Pro Thr Val Thr Thr Val Arg Thr Ser Thr 
        115                 120                 125             


Thr Val Pro Thr Thr Thr Thr Val Pro Met Thr Thr Val Pro Thr Thr 
    130                 135                 140                 


Thr Val Pro Thr Thr Met Ser Ile Pro Thr Thr Thr Thr Val Leu Thr 
145                 150                 155                 160 


Thr Met Thr Val Ser Thr Thr Thr Ser Val Pro Thr Thr Thr Ser Ile 
                165                 170                 175     


Pro Thr Thr Thr Ser Val Pro Val Thr Thr Thr Val Ser Thr Phe Val 
            180                 185                 190         


Pro Pro Met Pro Leu Pro Arg Gln Asn His Glu Pro Val Ala Thr Ser 
        195                 200                 205             


Pro Ser Ser Pro Gln Pro Ala Glu Thr His Pro Thr Thr Leu Gln Gly 
    210                 215                 220                 


Ala Ile Arg Arg Glu Pro Thr Ser Ser Pro Leu Tyr Ser Tyr Thr Thr 
225                 230                 235                 240 


Asp Gly Asn Asp Thr Val Thr Glu Ser Ser Asp Gly Leu Trp Asn Asn 
                245                 250                 255     


Asn Gln Thr Gln Leu Phe Leu Glu His Ser Leu Leu Thr Ala Asn Thr 
            260                 265                 270         


Thr Lys Gly 
        275 


<210>  536
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  536

Ser Glu Val Glu Tyr Arg Ala Glu Val Gly Gln Asn Ala Tyr Leu Pro 
1               5                   10                  15      


Cys Phe Tyr Thr Pro Ala Ala Pro Gly Asn Leu Val Pro Val Cys Trp 
            20                  25                  30          


Gly Lys Gly Ala Cys Pro Val Phe Glu Cys Gly Asn Val Val Leu Arg 
        35                  40                  45              


Thr Asp Glu Arg Asp Val Asn Tyr Trp Thr Ser Arg Tyr Trp Leu Asn 
    50                  55                  60                  


Gly Asp Phe Arg Lys Gly Asp Val Ser Leu Thr Ile Glu Asn Val Thr 
65                  70                  75                  80  


Leu Ala Asp Ser Gly Ile Tyr Cys Cys Arg Ile Gln Ile Pro Gly Ile 
                85                  90                  95      


Met Asn Asp Glu Lys Phe Asn Leu Lys Leu Val Ile Lys Pro Ala Lys 
            100                 105                 110         


Val Thr Pro Ala Pro Thr Leu Gln Arg Asp Phe Thr Ala Ala Phe Pro 
        115                 120                 125             


Arg Met Leu Thr Thr Arg Gly His Gly Pro Ala Glu Thr Gln Thr Leu 
    130                 135                 140                 


Gly Ser Leu Pro Asp Ile Asn Leu Thr Gln Ile Ser Thr Leu Ala Asn 
145                 150                 155                 160 


Glu Leu Arg Asp Ser Arg Leu Ala Asn Asp Leu Arg Asp Ser Gly Ala 
                165                 170                 175     


Thr Ile Arg Ile Gly 
            180     


<210>  537
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  537

Asp Leu Gln Glu Ala Asp Leu Asp Leu Leu Arg Val Thr Leu Ser Ser 
1               5                   10                  15      


Lys Pro Gln Ala Leu Ala Thr Pro Asn Lys Glu Glu His Gly Lys Arg 
            20                  25                  30          


Lys Lys Lys Gly Lys Gly Leu Gly Lys Lys Arg Asp Pro Cys Leu Arg 
        35                  40                  45              


Lys Tyr Lys Asp Phe Cys Ile His Gly Glu Cys Lys Tyr Val Lys Glu 
    50                  55                  60                  


Leu Arg Ala Pro Ser Cys Ile Cys His Pro Gly Tyr His Gly Glu Arg 
65                  70                  75                  80  


Cys His Gly Leu Ser Leu 
                85      


<210>  538
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  538

Val Asn Ile Thr Ser Pro Val Arg Leu Ile His Gly Thr Val Gly Lys 
1               5                   10                  15      


Ser Ala Leu Leu Ser Val Gln Tyr Ser Ser Thr Ser Ser Asp Arg Pro 
            20                  25                  30          


Val Val Lys Trp Gln Leu Lys Arg Asp Lys Pro Val Thr Val Val Gln 
        35                  40                  45              


Ser Ile Gly Thr Glu Val Ile Gly Thr Leu Arg Pro Asp Tyr Arg Asp 
    50                  55                  60                  


Arg Ile Arg Leu Phe Glu Asn Gly Ser Leu Leu Leu Ser Asp Leu Gln 
65                  70                  75                  80  


Leu Ala Asp Glu Gly Thr Tyr Glu Val Glu Ile Ser Ile Thr Asp Asp 
                85                  90                  95      


Thr Phe Thr Gly Glu Lys Thr Ile Asn Leu Thr Val Asp Val Pro Ile 
            100                 105                 110         


Ser Arg Pro Gln Val Leu Val Ala Ser Thr Thr Val Leu Glu Leu Ser 
        115                 120                 125             


Glu Ala Phe Thr Leu Asn Cys Ser His Glu Asn Gly Thr Lys Pro Ser 
    130                 135                 140                 


Tyr Thr Trp Leu Lys Asp Gly Lys Pro Leu Leu Asn Asp Ser Arg Met 
145                 150                 155                 160 


Leu Leu Ser Pro Asp Gln Lys Val Leu Thr Ile Thr Arg Val Leu Met 
                165                 170                 175     


Glu Asp Asp Asp Leu Tyr Ser Cys Met Val Glu Asn Pro Ile Ser Gln 
            180                 185                 190         


Gly Arg Ser Leu Pro Val Lys Ile Thr Val Tyr Arg Arg Ser Ser 
        195                 200                 205         


<210>  539
<211>  320
<212>  PRT
<213>  Homo Sapiens

<400>  539

Leu Lys Val Thr Val Pro Ser His Thr Val His Gly Val Arg Gly Gln 
1               5                   10                  15      


Ala Leu Tyr Leu Pro Val His Tyr Gly Phe His Thr Pro Ala Ser Asp 
            20                  25                  30          


Ile Gln Ile Ile Trp Leu Phe Glu Arg Pro His Thr Met Pro Lys Tyr 
        35                  40                  45              


Leu Leu Gly Ser Val Asn Lys Ser Val Val Pro Asp Leu Glu Tyr Gln 
    50                  55                  60                  


His Lys Phe Thr Met Met Pro Pro Asn Ala Ser Leu Leu Ile Asn Pro 
65                  70                  75                  80  


Leu Gln Phe Pro Asp Glu Gly Asn Tyr Ile Val Lys Val Asn Ile Gln 
                85                  90                  95      


Gly Asn Gly Thr Leu Ser Ala Ser Gln Lys Ile Gln Val Thr Val Asp 
            100                 105                 110         


Asp Pro Val Thr Lys Pro Val Val Gln Ile His Pro Pro Ser Gly Ala 
        115                 120                 125             


Val Glu Tyr Val Gly Asn Met Thr Leu Thr Cys His Val Glu Gly Gly 
    130                 135                 140                 


Thr Arg Leu Ala Tyr Gln Trp Leu Lys Asn Gly Arg Pro Val His Thr 
145                 150                 155                 160 


Ser Ser Thr Tyr Ser Phe Ser Pro Gln Asn Asn Thr Leu His Ile Ala 
                165                 170                 175     


Pro Val Thr Lys Glu Asp Ile Gly Asn Tyr Ser Cys Leu Val Arg Asn 
            180                 185                 190         


Pro Val Ser Glu Met Glu Ser Asp Ile Ile Met Pro Ile Ile Tyr Tyr 
        195                 200                 205             


Gly Pro Tyr Gly Leu Gln Val Asn Ser Asp Lys Gly Leu Lys Val Gly 
    210                 215                 220                 


Glu Val Phe Thr Val Asp Leu Gly Glu Ala Ile Leu Phe Asp Cys Ser 
225                 230                 235                 240 


Ala Asp Ser His Pro Pro Asn Thr Tyr Ser Trp Ile Arg Arg Thr Asp 
                245                 250                 255     


Asn Thr Thr Tyr Ile Ile Lys His Gly Pro Arg Leu Glu Val Ala Ser 
            260                 265                 270         


Glu Lys Val Ala Gln Lys Thr Met Asp Tyr Val Cys Cys Ala Tyr Asn 
        275                 280                 285             


Asn Ile Thr Gly Arg Gln Asp Glu Thr His Phe Thr Val Ile Ile Thr 
    290                 295                 300                 


Ser Val Gly Leu Glu Lys Leu Ala Gln Lys Gly Lys Ser Leu Ser Pro 
305                 310                 315                 320 


<210>  540
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  540

Arg Leu Leu Arg Ser His Ser Leu His Tyr Leu Phe Met Gly Ala Ser 
1               5                   10                  15      


Glu Gln Asp Leu Gly Leu Ser Leu Phe Glu Ala Leu Gly Tyr Val Asp 
            20                  25                  30          


Asp Gln Leu Phe Val Phe Tyr Asp His Glu Ser Arg Arg Val Glu Pro 
        35                  40                  45              


Arg Thr Pro Trp Val Ser Ser Arg Ile Ser Ser Gln Met Trp Leu Gln 
    50                  55                  60                  


Leu Ser Gln Ser Leu Lys Gly Trp Asp His Met Phe Thr Val Asp Phe 
65                  70                  75                  80  


Trp Thr Ile Met Glu Asn His Asn His Ser Lys Glu Ser His Thr Leu 
                85                  90                  95      


Gln Val Ile Leu Gly Cys Glu Met Gln Glu Asp Asn Ser Thr Glu Gly 
            100                 105                 110         


Tyr Trp Lys Tyr Gly Tyr Asp Gly Gln Asp His Leu Glu Phe Cys Pro 
        115                 120                 125             


Asp Thr Leu Asp Trp Arg Ala Ala Glu Pro Arg Ala Trp Pro Thr Lys 
    130                 135                 140                 


Leu Glu Trp Glu Arg His Lys Ile Arg Ala Arg Gln Asn Arg Ala Tyr 
145                 150                 155                 160 


Leu Glu Arg Asp Cys Pro Ala Gln Leu Gln Gln Leu Leu Glu Leu Gly 
                165                 170                 175     


Arg Gly Val Leu Asp Gln Gln Val Pro Pro Leu Val Lys Val Thr His 
            180                 185                 190         


His Val Thr Ser Ser Val Thr Thr Leu Arg Cys Arg Ala Leu Asn Tyr 
        195                 200                 205             


Tyr Pro Gln Asn Ile Thr Met Lys Trp Leu Lys Asp Lys Gln Pro Met 
    210                 215                 220                 


Asp Ala Lys Glu Phe Glu Pro Lys Asp Val Leu Pro Asn Gly Asp Gly 
225                 230                 235                 240 


Thr Tyr Gln Gly Trp Ile Thr Leu Ala Val Pro Pro Gly Glu Glu Gln 
                245                 250                 255     


Arg Tyr Thr Cys Gln Val Glu His Pro Gly Leu Asp Gln Pro Leu Ile 
            260                 265                 270         


Val Ile Trp Glu Pro Ser Pro Ser Gly Thr Leu Val 
        275                 280                 


<210>  541
<211>  697
<212>  PRT
<213>  Homo Sapiens

<400>  541

Gln Arg Lys Arg Arg Asn Thr Ile His Glu Phe Lys Lys Ser Ala Lys 
1               5                   10                  15      


Thr Thr Leu Ile Lys Ile Asp Pro Ala Leu Lys Ile Lys Thr Lys Lys 
            20                  25                  30          


Val Asn Thr Ala Asp Gln Cys Ala Asn Arg Cys Thr Arg Asn Lys Gly 
        35                  40                  45              


Leu Pro Phe Thr Cys Lys Ala Phe Val Phe Asp Lys Ala Arg Lys Gln 
    50                  55                  60                  


Cys Leu Trp Phe Pro Phe Asn Ser Met Ser Ser Gly Val Lys Lys Glu 
65                  70                  75                  80  


Phe Gly His Glu Phe Asp Leu Tyr Glu Asn Lys Asp Tyr Ile Arg Asn 
                85                  90                  95      


Cys Ile Ile Gly Lys Gly Arg Ser Tyr Lys Gly Thr Val Ser Ile Thr 
            100                 105                 110         


Lys Ser Gly Ile Lys Cys Gln Pro Trp Ser Ser Met Ile Pro His Glu 
        115                 120                 125             


His Ser Phe Leu Pro Ser Ser Tyr Arg Gly Lys Asp Leu Gln Glu Asn 
    130                 135                 140                 


Tyr Cys Arg Asn Pro Arg Gly Glu Glu Gly Gly Pro Trp Cys Phe Thr 
145                 150                 155                 160 


Ser Asn Pro Glu Val Arg Tyr Glu Val Cys Asp Ile Pro Gln Cys Ser 
                165                 170                 175     


Glu Val Glu Cys Met Thr Cys Asn Gly Glu Ser Tyr Arg Gly Leu Met 
            180                 185                 190         


Asp His Thr Glu Ser Gly Lys Ile Cys Gln Arg Trp Asp His Gln Thr 
        195                 200                 205             


Pro His Arg His Lys Phe Leu Pro Glu Arg Tyr Pro Asp Lys Gly Phe 
    210                 215                 220                 


Asp Asp Asn Tyr Cys Arg Asn Pro Asp Gly Gln Pro Arg Pro Trp Cys 
225                 230                 235                 240 


Tyr Thr Leu Asp Pro His Thr Arg Trp Glu Tyr Cys Ala Ile Lys Thr 
                245                 250                 255     


Cys Ala Asp Asn Thr Met Asn Asp Thr Asp Val Pro Leu Glu Thr Thr 
            260                 265                 270         


Glu Cys Ile Gln Gly Gln Gly Glu Gly Tyr Arg Gly Thr Val Asn Thr 
        275                 280                 285             


Ile Trp Asn Gly Ile Pro Cys Gln Arg Trp Asp Ser Gln Tyr Pro His 
    290                 295                 300                 


Glu His Asp Met Thr Pro Glu Asn Phe Lys Cys Lys Asp Leu Arg Glu 
305                 310                 315                 320 


Asn Tyr Cys Arg Asn Pro Asp Gly Ser Glu Ser Pro Trp Cys Phe Thr 
                325                 330                 335     


Thr Asp Pro Asn Ile Arg Val Gly Tyr Cys Ser Gln Ile Pro Asn Cys 
            340                 345                 350         


Asp Met Ser His Gly Gln Asp Cys Tyr Arg Gly Asn Gly Lys Asn Tyr 
        355                 360                 365             


Met Gly Asn Leu Ser Gln Thr Arg Ser Gly Leu Thr Cys Ser Met Trp 
    370                 375                 380                 


Asp Lys Asn Met Glu Asp Leu His Arg His Ile Phe Trp Glu Pro Asp 
385                 390                 395                 400 


Ala Ser Lys Leu Asn Glu Asn Tyr Cys Arg Asn Pro Asp Asp Asp Ala 
                405                 410                 415     


His Gly Pro Trp Cys Tyr Thr Gly Asn Pro Leu Ile Pro Trp Asp Tyr 
            420                 425                 430         


Cys Pro Ile Ser Arg Cys Glu Gly Asp Thr Thr Pro Thr Ile Val Asn 
        435                 440                 445             


Leu Asp His Pro Val Ile Ser Cys Ala Lys Thr Lys Gln Leu Arg Val 
    450                 455                 460                 


Val Asn Gly Ile Pro Thr Arg Thr Asn Ile Gly Trp Met Val Ser Leu 
465                 470                 475                 480 


Arg Tyr Arg Asn Lys His Ile Cys Gly Gly Ser Leu Ile Lys Glu Ser 
                485                 490                 495     


Trp Val Leu Thr Ala Arg Gln Cys Phe Pro Ser Arg Asp Leu Lys Asp 
            500                 505                 510         


Tyr Glu Ala Trp Leu Gly Ile His Asp Val His Gly Arg Gly Asp Glu 
        515                 520                 525             


Lys Cys Lys Gln Val Leu Asn Val Ser Gln Leu Val Tyr Gly Pro Glu 
    530                 535                 540                 


Gly Ser Asp Leu Val Leu Met Lys Leu Ala Arg Pro Ala Val Leu Asp 
545                 550                 555                 560 


Asp Phe Val Ser Thr Ile Asp Leu Pro Asn Tyr Gly Cys Thr Ile Pro 
                565                 570                 575     


Glu Lys Thr Ser Cys Ser Val Tyr Gly Trp Gly Tyr Thr Gly Leu Ile 
            580                 585                 590         


Asn Tyr Asp Gly Leu Leu Arg Val Ala His Leu Tyr Ile Met Gly Asn 
        595                 600                 605             


Glu Lys Cys Ser Gln His His Arg Gly Lys Val Thr Leu Asn Glu Ser 
    610                 615                 620                 


Glu Ile Cys Ala Gly Ala Glu Lys Ile Gly Ser Gly Pro Cys Glu Gly 
625                 630                 635                 640 


Asp Tyr Gly Gly Pro Leu Val Cys Glu Gln His Lys Met Arg Met Val 
                645                 650                 655     


Leu Gly Val Ile Val Pro Gly Arg Gly Cys Ala Ile Pro Asn Arg Pro 
            660                 665                 670         


Gly Ile Phe Val Arg Val Ala Tyr Tyr Ala Lys Trp Ile His Lys Ile 
        675                 680                 685             


Ile Leu Thr Tyr Lys Val Pro Gln Ser 
    690                 695         


<210>  542
<211>  283
<212>  PRT
<213>  Homo Sapiens

<400>  542

Val Gln Leu Ser Pro Asp Leu Leu Ala Thr Leu Pro Glu Pro Ala Ser 
1               5                   10                  15      


Pro Gly Arg Gln Ala Cys Gly Arg Arg His Lys Lys Arg Thr Phe Leu 
            20                  25                  30          


Arg Pro Arg Ile Ile Gly Gly Ser Ser Ser Leu Pro Gly Ser His Pro 
        35                  40                  45              


Trp Leu Ala Ala Ile Tyr Ile Gly Asp Ser Phe Cys Ala Gly Ser Leu 
    50                  55                  60                  


Val His Thr Cys Trp Val Val Ser Ala Ala His Cys Phe Ser His Ser 
65                  70                  75                  80  


Pro Pro Arg Asp Ser Val Ser Val Val Leu Gly Gln His Phe Phe Asn 
                85                  90                  95      


Arg Thr Thr Asp Val Thr Gln Thr Phe Gly Ile Glu Lys Tyr Ile Pro 
            100                 105                 110         


Tyr Thr Leu Tyr Ser Val Phe Asn Pro Ser Asp His Asp Leu Val Leu 
        115                 120                 125             


Ile Arg Leu Lys Lys Lys Gly Asp Arg Cys Ala Thr Arg Ser Gln Phe 
    130                 135                 140                 


Val Gln Pro Ile Cys Leu Pro Glu Pro Gly Ser Thr Phe Pro Ala Gly 
145                 150                 155                 160 


His Lys Cys Gln Ile Ala Gly Trp Gly His Leu Asp Glu Asn Val Ser 
                165                 170                 175     


Gly Tyr Ser Ser Ser Leu Arg Glu Ala Leu Val Pro Leu Val Ala Asp 
            180                 185                 190         


His Lys Cys Ser Ser Pro Glu Val Tyr Gly Ala Asp Ile Ser Pro Asn 
        195                 200                 205             


Met Leu Cys Ala Gly Tyr Phe Asp Cys Lys Ser Asp Ala Cys Gln Gly 
    210                 215                 220                 


Asp Ser Gly Gly Pro Leu Ala Cys Glu Lys Asn Gly Val Ala Tyr Leu 
225                 230                 235                 240 


Tyr Gly Ile Ile Ser Trp Gly Asp Gly Cys Gly Arg Leu His Lys Pro 
                245                 250                 255     


Gly Val Tyr Thr Arg Val Ala Asn Tyr Val Asp Trp Ile Asn Asp Arg 
            260                 265                 270         


Ile Arg Pro Pro Arg Arg Leu Val Ala Pro Ser 
        275                 280             


<210>  543
<211>  683
<212>  PRT
<213>  Homo Sapiens

<400>  543

Phe Phe Glu Gly Asp Ala Lys Phe Gly Glu Arg Asn Glu Gly Ser Gly 
1               5                   10                  15      


Ala Arg Arg Arg Arg Cys Leu Asn Gly Asn Pro Pro Lys Arg Leu Lys 
            20                  25                  30          


Arg Arg Asp Arg Arg Met Met Ser Gln Leu Glu Leu Leu Ser Gly Gly 
        35                  40                  45              


Glu Met Leu Cys Gly Gly Phe Tyr Pro Arg Leu Ser Cys Cys Leu Arg 
    50                  55                  60                  


Ser Asp Ser Pro Gly Leu Gly Arg Leu Glu Asn Lys Ile Phe Ser Val 
65                  70                  75                  80  


Thr Asn Asn Thr Glu Cys Gly Lys Leu Leu Glu Glu Ile Lys Cys Ala 
                85                  90                  95      


Leu Cys Ser Pro His Ser Gln Ser Leu Phe His Ser Pro Glu Arg Glu 
            100                 105                 110         


Val Leu Glu Arg Asp Leu Val Leu Pro Leu Leu Cys Lys Asp Tyr Cys 
        115                 120                 125             


Lys Glu Phe Phe Tyr Thr Cys Arg Gly His Ile Pro Gly Phe Leu Gln 
    130                 135                 140                 


Thr Thr Ala Asp Glu Phe Cys Phe Tyr Tyr Ala Arg Lys Asp Gly Gly 
145                 150                 155                 160 


Leu Cys Phe Pro Asp Phe Pro Arg Lys Gln Val Arg Gly Pro Ala Ser 
                165                 170                 175     


Asn Tyr Leu Asp Gln Met Glu Glu Tyr Asp Lys Val Glu Glu Ile Ser 
            180                 185                 190         


Arg Lys His Lys His Asn Cys Phe Cys Ile Gln Glu Val Val Ser Gly 
        195                 200                 205             


Leu Arg Gln Pro Val Gly Ala Leu His Ser Gly Asp Gly Ser Gln Arg 
    210                 215                 220                 


Leu Phe Ile Leu Glu Lys Glu Gly Tyr Val Lys Ile Leu Thr Pro Glu 
225                 230                 235                 240 


Gly Glu Ile Phe Lys Glu Pro Tyr Leu Asp Ile His Lys Leu Val Gln 
                245                 250                 255     


Ser Gly Ile Lys Gly Gly Asp Glu Arg Gly Leu Leu Ser Leu Ala Phe 
            260                 265                 270         


His Pro Asn Tyr Lys Lys Asn Gly Lys Leu Tyr Val Ser Tyr Thr Thr 
        275                 280                 285             


Asn Gln Glu Arg Trp Ala Ile Gly Pro His Asp His Ile Leu Arg Val 
    290                 295                 300                 


Val Glu Tyr Thr Val Ser Arg Lys Asn Pro His Gln Val Asp Leu Arg 
305                 310                 315                 320 


Thr Ala Arg Val Phe Leu Glu Val Ala Glu Leu His Arg Lys His Leu 
                325                 330                 335     


Gly Gly Gln Leu Leu Phe Gly Pro Asp Gly Phe Leu Tyr Ile Ile Leu 
            340                 345                 350         


Gly Asp Gly Met Ile Thr Leu Asp Asp Met Glu Glu Met Asp Gly Leu 
        355                 360                 365             


Ser Asp Phe Thr Gly Ser Val Leu Arg Leu Asp Val Asp Thr Asp Met 
    370                 375                 380                 


Cys Asn Val Pro Tyr Ser Ile Pro Arg Ser Asn Pro His Phe Asn Ser 
385                 390                 395                 400 


Thr Asn Gln Pro Pro Glu Val Phe Ala His Gly Leu His Asp Pro Gly 
                405                 410                 415     


Arg Cys Ala Val Asp Arg His Pro Thr Asp Ile Asn Ile Asn Leu Thr 
            420                 425                 430         


Ile Leu Cys Ser Asp Ser Asn Gly Lys Asn Arg Ser Ser Ala Arg Ile 
        435                 440                 445             


Leu Gln Ile Ile Lys Gly Lys Asp Tyr Glu Ser Glu Pro Ser Leu Leu 
    450                 455                 460                 


Glu Phe Lys Pro Phe Ser Asn Gly Pro Leu Val Gly Gly Phe Val Tyr 
465                 470                 475                 480 


Arg Gly Cys Gln Ser Glu Arg Leu Tyr Gly Ser Tyr Val Phe Gly Asp 
                485                 490                 495     


Arg Asn Gly Asn Phe Leu Thr Leu Gln Gln Ser Pro Val Thr Lys Gln 
            500                 505                 510         


Trp Gln Glu Lys Pro Leu Cys Leu Gly Thr Ser Gly Ser Cys Arg Gly 
        515                 520                 525             


Tyr Phe Ser Gly His Ile Leu Gly Phe Gly Glu Asp Glu Leu Gly Glu 
    530                 535                 540                 


Val Tyr Ile Leu Ser Ser Ser Lys Ser Met Thr Gln Thr His Asn Gly 
545                 550                 555                 560 


Lys Leu Tyr Lys Ile Val Asp Pro Lys Arg Pro Leu Met Pro Glu Glu 
                565                 570                 575     


Cys Arg Ala Thr Val Gln Pro Ala Gln Thr Leu Thr Ser Glu Cys Ser 
            580                 585                 590         


Arg Leu Cys Arg Asn Gly Tyr Cys Thr Pro Thr Gly Lys Cys Cys Cys 
        595                 600                 605             


Ser Pro Gly Trp Glu Gly Asp Phe Cys Arg Thr Ala Lys Cys Glu Pro 
    610                 615                 620                 


Ala Cys Arg His Gly Gly Val Cys Val Arg Pro Asn Lys Cys Leu Cys 
625                 630                 635                 640 


Lys Lys Gly Tyr Leu Gly Pro Gln Cys Glu Gln Val Asp Arg Asn Ile 
                645                 650                 655     


Arg Arg Val Thr Arg Ala Gly Ile Leu Asp Gln Ile Ile Asp Met Thr 
            660                 665                 670         


Ser Tyr Leu Leu Asp Leu Thr Ser Tyr Ile Val 
        675                 680             


<210>  544
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  544

Ile Phe Pro Leu Ala Phe Phe Ile Tyr Val Pro Met Asn Glu Gln Ile 
1               5                   10                  15      


Val Ile Gly Arg Leu Asp Glu Asp Ile Ile Leu Pro Ser Ser Phe Glu 
            20                  25                  30          


Arg Gly Ser Glu Val Val Ile His Trp Lys Tyr Gln Asp Ser Tyr Lys 
        35                  40                  45              


Val His Ser Tyr Tyr Lys Gly Ser Asp His Leu Glu Ser Gln Asp Pro 
    50                  55                  60                  


Arg Tyr Ala Asn Arg Thr Ser Leu Phe Tyr Asn Glu Ile Gln Asn Gly 
65                  70                  75                  80  


Asn Ala Ser Leu Phe Phe Arg Arg Val Ser Leu Leu Asp Glu Gly Ile 
                85                  90                  95      


Tyr Thr Cys Tyr Val Gly Thr Ala Ile Gln Val Ile Thr Asn Lys Val 
            100                 105                 110         


Val Leu Lys Val Gly Val Phe Leu Thr Pro Val Met Lys Tyr Glu Lys 
        115                 120                 125             


Arg Asn Thr Asn Ser Phe Leu Ile Cys Ser Val Leu Ser Val Tyr Pro 
    130                 135                 140                 


Arg Pro Ile Ile Thr Trp Lys Met Asp Asn Thr Pro Ile Ser Glu Asn 
145                 150                 155                 160 


Asn Met Glu Glu Thr Gly Ser Leu Asp Ser Phe Ser Ile Asn Ser Pro 
                165                 170                 175     


Leu Asn Ile Thr Gly Ser Asn Ser Ser Tyr Glu Cys Thr Ile Glu Asn 
            180                 185                 190         


Ser Leu Leu Lys Gln Thr Trp Thr Gly Arg Trp Thr Met Lys Asp Gly 
        195                 200                 205             


Leu His Lys Met Gln Ser Glu His Val Ser Leu Ser Cys Gln Pro Val 
    210                 215                 220                 


Asn Asp Tyr Phe Ser Pro Asn Gln Asp Phe Lys Val Thr Trp Ser Arg 
225                 230                 235                 240 


Met Lys Ser Gly Thr Phe Ser Val Leu Ala Tyr Tyr Leu Ser Ser Ser 
                245                 250                 255     


Gln Asn Thr Ile Ile Asn Glu Ser Arg Phe Ser Trp Asn Lys Glu Leu 
            260                 265                 270         


Ile Asn Gln Ser Asp Phe Ser Met Asn Leu Met Asp Leu Asn Leu Ser 
        275                 280                 285             


Asp Ser Gly Glu Tyr Leu Cys Asn Ile Ser Ser Asp Glu Tyr Thr Leu 
    290                 295                 300                 


Leu Thr Ile His Thr Val His Val Glu Pro Ser Gln Glu Thr Ala Ser 
305                 310                 315                 320 


His Asn 
        


<210>  545
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  545

Arg Ser His Ser Met Arg Tyr Phe Tyr Thr Thr Met Ser Arg Pro Gly 
1               5                   10                  15      


Ala Gly Glu Pro Arg Phe Ile Ser Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Asp Ala Ser Pro Arg Glu Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Met Glu Arg Glu Gly Pro Lys Tyr Trp Asp Arg Asn Thr 
    50                  55                  60                  


Gln Ile Cys Lys Ala Gln Ala Gln Thr Glu Arg Glu Asn Leu Arg Ile 
65                  70                  75                  80  


Ala Leu Arg Tyr Tyr Asn Gln Ser Glu Gly Gly Ser His Thr Met Gln 
                85                  90                  95      


Val Met Tyr Gly Cys Asp Val Gly Pro Asp Gly Pro Phe Leu Arg Gly 
            100                 105                 110         


Tyr Glu Gln His Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Met Ala Ala Gln Ile Thr Lys 
    130                 135                 140                 


Arg Lys Trp Glu Ala Ala Arg Arg Ala Glu Gln Arg Arg Val Tyr Leu 
145                 150                 155                 160 


Glu Gly Glu Phe Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Asp Pro Pro Lys Thr His Met Thr His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Glu Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Pro Thr Val Pro Ile 
        275                 280                 


<210>  546
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  546

Gly Ser His Ser Met Arg Tyr Phe Tyr Thr Ala Met Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ser Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Pro Arg Glu Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Arg Asn Thr 
    50                  55                  60                  


Gln Ile Cys Lys Thr Asn Thr Gln Thr Tyr Arg Glu Ser Leu Arg Asn 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Leu Gln 
                85                  90                  95      


Arg Met Tyr Gly Cys Asp Val Gly Pro Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


His Asp Gln Tyr Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Ser Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Lys Trp Glu Ala Ala Arg Glu Ala Glu Gln Leu Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Leu Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Asp Pro Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Arg Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Ser Thr Ile Pro Ile Val 
        275                 280                 285 


<210>  547
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  547

Gly Ser His Ser Met Arg Tyr Phe Tyr Thr Ser Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Gln Arg Met Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Arg Asn Thr 
    50                  55                  60                  


Arg Asn Val Lys Ala His Ser Gln Thr Asp Arg Glu Ser Leu Arg Ile 
65                  70                  75                  80  


Ala Leu Arg Tyr Tyr Asn Gln Ser Glu Asp Gly Ser His Thr Ile Gln 
                85                  90                  95      


Arg Met Tyr Gly Cys Asp Val Gly Pro Asp Gly Arg Phe Leu Arg Gly 
            100                 105                 110         


Tyr Gln Gln Asp Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Met Ala Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Lys Trp Glu Thr Ala His Glu Ala Glu Gln Trp Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Arg Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Thr Asp Ala Pro Lys Thr His Met Thr His His 
            180                 185                 190         


Ala Val Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Ser Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ser Val Val Val Pro Ser Gly Gln Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  548
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  548

Gly Ser His Ser Met Arg Tyr Phe Phe Thr Ser Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Gln Arg Met Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Gly Glu Thr 
    50                  55                  60                  


Arg Lys Val Lys Ala His Ser Gln Thr His Arg Val Asp Leu Gly Thr 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Val Gln 
                85                  90                  95      


Arg Met Tyr Gly Cys Asp Val Gly Ser Asp Trp Arg Phe Leu Arg Gly 
            100                 105                 110         


Tyr His Gln Tyr Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Lys Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Met Ala Ala Gln Thr Thr Lys 
    130                 135                 140                 


His Lys Trp Glu Ala Ala His Val Ala Glu Gln Leu Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Thr Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Thr Asp Ala Pro Lys Thr His Met Thr His His 
            180                 185                 190         


Ala Val Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Ser Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Gln Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  549
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  549

Gly Ser His Ser Met Arg Tyr Phe Tyr Thr Ala Met Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Pro Arg Thr Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Arg Asn Thr 
    50                  55                  60                  


Gln Ile Phe Lys Thr Asn Thr Gln Thr Tyr Arg Glu Ser Leu Arg Asn 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Ile Ile Gln 
                85                  90                  95      


Arg Met Tyr Gly Cys Asp Leu Gly Pro Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


His Asp Gln Ser Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Ser Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Lys Trp Glu Ala Ala Arg Val Ala Glu Gln Leu Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Leu Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Asp Pro Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Pro Val Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Arg Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Ser Thr Ile Pro Ile 
        275                 280                 


<210>  550
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  550

Gly Ser His Ser Met Arg Tyr Phe Phe Thr Ser Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Gln Lys Met Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Gln Glu Thr 
    50                  55                  60                  


Arg Asn Met Lys Ala His Ser Gln Thr Asp Arg Ala Asn Leu Gly Thr 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Asp Gly Ser His Thr Ile Gln 
                85                  90                  95      


Ile Met Tyr Gly Cys Asp Val Gly Pro Asp Gly Arg Phe Leu Arg Gly 
            100                 105                 110         


Tyr Arg Gln Asp Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Met Ala Ala Gln Ile Thr Lys 
    130                 135                 140                 


Arg Lys Trp Glu Ala Val His Ala Ala Glu Gln Arg Arg Val Tyr Leu 
145                 150                 155                 160 


Glu Gly Arg Cys Val Asp Gly Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Thr Asp Pro Pro Lys Thr His Met Thr His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Leu Ser Ser Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  551
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  551

Gly Ser His Ser Met Arg Tyr Phe Tyr Thr Ala Met Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ser Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Pro Arg Glu Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Ile Glu Gln Glu Gly Pro Glu Tyr Trp Asp Arg Asn Thr 
    50                  55                  60                  


Gln Ile Cys Lys Thr Asn Thr Gln Thr Tyr Arg Glu Ser Leu Arg Asn 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Leu Gln 
                85                  90                  95      


Arg Met Tyr Gly Cys Asp Val Gly Pro Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


His Asp Gln Tyr Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Ser Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Lys Trp Glu Ala Ala Arg Glu Ala Glu Gln Leu Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Leu Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Asp Pro Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Arg Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Lys Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Ser Thr Ile Pro Ile Val 
        275                 280                 285 


<210>  552
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  552

Cys Ser His Ser Met Arg Tyr Phe Tyr Thr Ala Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ala Ala Ser Pro Arg Gly Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Val Glu Gln Glu Gly Pro Glu Tyr Trp Asp Arg Glu Thr 
    50                  55                  60                  


Gln Lys Tyr Lys Arg Gln Ala Gln Thr Asp Arg Val Ser Leu Arg Asn 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Leu Gln 
                85                  90                  95      


Trp Met Tyr Gly Cys Asp Leu Gly Pro Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


Tyr Asp Gln Ser Ala Tyr Asp Gly Lys Asp Tyr Ile Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Lys Trp Glu Ala Ala Arg Ala Ala Glu Gln Gln Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Thr Cys Val Glu Trp Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Glu His Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Leu Val Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Glu Pro Leu Thr Leu 
            260                 265                 270         


Arg Trp Glu Pro Ser Ser Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  553
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  553

Val Pro Glu Ala Pro Thr Pro Met Trp Pro Asp Asp Leu Gln Asn His 
1               5                   10                  15      


Thr Phe Leu His Thr Val Tyr Cys Gln Asp Gly Ser Pro Ser Val Gly 
            20                  25                  30          


Leu Ser Glu Ala Tyr Asp Glu Asp Gln Leu Phe Phe Phe Asp Phe Ser 
        35                  40                  45              


Gln Asn Thr Arg Val Pro Arg Leu Pro Glu Phe Ala Asp Trp Ala Gln 
    50                  55                  60                  


Glu Gln Gly Asp Ala Pro Ala Ile Leu Phe Asp Lys Glu Phe Cys Glu 
65                  70                  75                  80  


Trp Met Ile Gln Gln Ile Gly Pro Lys Leu Asp Gly Lys Ile Pro Val 
                85                  90                  95      


Ser Arg Gly Phe Pro Ile Ala Glu Val Phe Thr Leu Lys Pro Leu Glu 
            100                 105                 110         


Phe Gly Lys Pro Asn Thr Leu Val Cys Phe Val Ser Asn Leu Phe Pro 
        115                 120                 125             


Pro Met Leu Thr Val Asn Trp Gln His His Ser Val Pro Val Glu Gly 
    130                 135                 140                 


Phe Gly Pro Thr Phe Val Ser Ala Val Asp Gly Leu Ser Phe Gln Ala 
145                 150                 155                 160 


Phe Ser Tyr Leu Asn Phe Thr Pro Glu Pro Ser Asp Ile Phe Ser Cys 
                165                 170                 175     


Ile Val Thr His Glu Ile Asp Arg Tyr Thr Ala Ile Ala Tyr Trp Val 
            180                 185                 190         


Pro Arg Asn Ala Leu Pro Ser Asp Leu Leu Glu Asn Val Leu Cys 
        195                 200                 205         


<210>  554
<211>  200
<212>  PRT
<213>  Homo Sapiens

<400>  554

Gly Gly Phe Val Ala His Val Glu Ser Thr Cys Leu Leu Asp Asp Ala 
1               5                   10                  15      


Gly Thr Pro Lys Asp Phe Thr Tyr Cys Ile Ser Phe Asn Lys Asp Leu 
            20                  25                  30          


Leu Thr Cys Trp Asp Pro Glu Glu Asn Lys Met Ala Pro Cys Glu Phe 
        35                  40                  45              


Gly Val Leu Asn Ser Leu Ala Asn Val Leu Ser Gln His Leu Asn Gln 
    50                  55                  60                  


Lys Asp Thr Leu Met Gln Arg Leu Arg Asn Gly Leu Gln Asn Cys Ala 
65                  70                  75                  80  


Thr His Thr Gln Pro Phe Trp Gly Ser Leu Thr Asn Arg Thr Arg Pro 
                85                  90                  95      


Pro Ser Val Gln Val Ala Lys Thr Thr Pro Phe Asn Thr Arg Glu Pro 
            100                 105                 110         


Val Met Leu Ala Cys Tyr Val Trp Gly Phe Tyr Pro Ala Glu Val Thr 
        115                 120                 125             


Ile Thr Trp Arg Lys Asn Gly Lys Leu Val Met Pro His Ser Ser Ala 
    130                 135                 140                 


His Lys Thr Ala Gln Pro Asn Gly Asp Trp Thr Tyr Gln Thr Leu Ser 
145                 150                 155                 160 


His Leu Ala Leu Thr Pro Ser Tyr Gly Asp Thr Tyr Thr Cys Val Val 
                165                 170                 175     


Glu His Ile Gly Ala Pro Glu Pro Ile Leu Arg Asp Trp Thr Pro Gly 
            180                 185                 190         


Leu Ser Pro Met Gln Thr Leu Lys 
        195                 200 


<210>  555
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  555

Thr Lys Ala Asp His Met Gly Ser Tyr Gly Pro Ala Phe Tyr Gln Ser 
1               5                   10                  15      


Tyr Gly Ala Ser Gly Gln Phe Thr His Glu Phe Asp Glu Glu Gln Leu 
            20                  25                  30          


Phe Ser Val Asp Leu Lys Lys Ser Glu Ala Val Trp Arg Leu Pro Glu 
        35                  40                  45              


Phe Gly Asp Phe Ala Arg Phe Asp Pro Gln Gly Gly Leu Ala Gly Ile 
    50                  55                  60                  


Ala Ala Ile Lys Ala His Leu Asp Ile Leu Val Glu Arg Ser Asn Arg 
65                  70                  75                  80  


Ser Arg Ala Ile Asn Val Pro Pro Arg Val Thr Val Leu Pro Lys Ser 
                85                  90                  95      


Arg Val Glu Leu Gly Gln Pro Asn Ile Leu Ile Cys Ile Val Asp Asn 
            100                 105                 110         


Ile Phe Pro Pro Val Ile Asn Ile Thr Trp Leu Arg Asn Gly Gln Thr 
        115                 120                 125             


Val Thr Glu Gly Val Ala Gln Thr Ser Phe Tyr Ser Gln Pro Asp His 
    130                 135                 140                 


Leu Phe Arg Lys Phe His Tyr Leu Pro Phe Val Pro Ser Ala Glu Asp 
145                 150                 155                 160 


Val Tyr Asp Cys Gln Val Glu His Trp Gly Leu Asp Ala Pro Leu Leu 
                165                 170                 175     


Arg His Trp Glu Leu Gln Val Pro Ile Pro Pro Pro Asp Ala Met Glu 
            180                 185                 190         


<210>  556
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  556

Thr Asp Ser Pro Glu Asp Phe Val Ile Gln Ala Lys Ala Asp Cys Tyr 
1               5                   10                  15      


Phe Thr Asn Gly Thr Glu Lys Val Gln Phe Val Val Arg Phe Ile Phe 
            20                  25                  30          


Asn Leu Glu Glu Tyr Val Arg Phe Asp Ser Asp Val Gly Met Phe Val 
        35                  40                  45              


Ala Leu Thr Lys Leu Gly Gln Pro Asp Ala Glu Gln Trp Asn Ser Arg 
    50                  55                  60                  


Leu Asp Leu Leu Glu Arg Ser Arg Gln Ala Val Asp Gly Val Cys Arg 
65                  70                  75                  80  


His Asn Tyr Arg Leu Gly Ala Pro Phe Thr Val Gly Arg Lys Val Gln 
                85                  90                  95      


Pro Glu Val Thr Val Tyr Pro Glu Arg Thr Pro Leu Leu His Gln His 
            100                 105                 110         


Asn Leu Leu His Cys Ser Val Thr Gly Phe Tyr Pro Gly Asp Ile Lys 
        115                 120                 125             


Ile Lys Trp Phe Leu Asn Gly Gln Glu Glu Arg Ala Gly Val Met Ser 
    130                 135                 140                 


Thr Gly Pro Ile Arg Asn Gly Asp Trp Thr Phe Gln Thr Val Val Met 
145                 150                 155                 160 


Leu Glu Met Thr Pro Glu Leu Gly His Val Tyr Thr Cys Leu Val Asp 
                165                 170                 175     


His Ser Ser Leu Leu Ser Pro Val Ser Val Glu Trp Arg Ala Gln Ser 
            180                 185                 190         


Glu Tyr Ser Trp Arg Lys 
        195             


<210>  557
<211>  194
<212>  PRT
<213>  Homo Sapiens

<400>  557

Ala Gly Ala Ile Lys Ala Asp His Val Ser Thr Tyr Ala Ala Phe Val 
1               5                   10                  15      


Gln Thr His Arg Pro Thr Gly Glu Phe Met Phe Glu Phe Asp Glu Asp 
            20                  25                  30          


Glu Gln Phe Tyr Val Asp Leu Asp Lys Lys Glu Thr Val Trp His Leu 
        35                  40                  45              


Glu Glu Phe Gly Arg Ala Phe Ser Phe Glu Ala Gln Gly Gly Leu Ala 
    50                  55                  60                  


Asn Ile Ala Ile Leu Asn Asn Asn Leu Asn Thr Leu Ile Gln Arg Ser 
65                  70                  75                  80  


Asn His Thr Gln Ala Ala Asn Asp Pro Pro Glu Val Thr Val Phe Pro 
                85                  90                  95      


Lys Glu Pro Val Glu Leu Gly Gln Pro Asn Thr Leu Ile Cys His Ile 
            100                 105                 110         


Asp Arg Phe Phe Pro Pro Val Leu Asn Val Thr Trp Leu Cys Asn Gly 
        115                 120                 125             


Glu Pro Val Thr Glu Gly Val Ala Glu Ser Leu Phe Leu Pro Arg Thr 
    130                 135                 140                 


Asp Tyr Ser Phe His Lys Phe His Tyr Leu Thr Phe Val Pro Ser Ala 
145                 150                 155                 160 


Glu Asp Val Tyr Asp Cys Arg Val Glu His Trp Gly Leu Asp Gln Pro 
                165                 170                 175     


Leu Leu Lys His Trp Glu Ala Gln Glu Pro Ile Gln Met Pro Glu Thr 
            180                 185                 190         


Thr Glu 
        


<210>  558
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  558

Arg Ala Thr Pro Glu Asn Tyr Leu Phe Gln Gly Arg Gln Glu Cys Tyr 
1               5                   10                  15      


Ala Phe Asn Gly Thr Gln Arg Phe Leu Glu Arg Tyr Ile Tyr Asn Arg 
            20                  25                  30          


Glu Glu Phe Val Arg Phe Asp Ser Asp Val Gly Glu Phe Arg Ala Val 
        35                  40                  45              


Thr Glu Leu Gly Arg Pro Ala Ala Glu Tyr Trp Asn Ser Gln Lys Asp 
    50                  55                  60                  


Ile Leu Glu Glu Lys Arg Ala Val Pro Asp Arg Met Cys Arg His Asn 
65                  70                  75                  80  


Tyr Glu Leu Gly Gly Pro Met Thr Leu Gln Arg Arg Val Gln Pro Arg 
                85                  90                  95      


Val Asn Val Ser Pro Ser Lys Lys Gly Pro Leu Gln His His Asn Leu 
            100                 105                 110         


Leu Val Cys His Val Thr Asp Phe Tyr Pro Gly Ser Ile Gln Val Arg 
        115                 120                 125             


Trp Phe Leu Asn Gly Gln Glu Glu Thr Ala Gly Val Val Ser Thr Asn 
    130                 135                 140                 


Leu Ile Arg Asn Gly Asp Trp Thr Phe Gln Ile Leu Val Met Leu Glu 
145                 150                 155                 160 


Met Thr Pro Gln Gln Gly Asp Val Tyr Thr Cys Gln Val Glu His Thr 
                165                 170                 175     


Ser Leu Asp Ser Pro Val Thr Val Glu Trp Lys Ala Gln Ser Asp Ser 
            180                 185                 190         


Ala Arg Ser Lys 
        195     


<210>  559
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  559

Glu Asp Ile Val Ala Asp His Val Ala Ser Tyr Gly Val Asn Leu Tyr 
1               5                   10                  15      


Gln Ser Tyr Gly Pro Ser Gly Gln Tyr Thr His Glu Phe Asp Gly Asp 
            20                  25                  30          


Glu Gln Phe Tyr Val Asp Leu Gly Arg Lys Glu Thr Val Trp Cys Leu 
        35                  40                  45              


Pro Val Leu Arg Gln Phe Arg Phe Asp Pro Gln Phe Ala Leu Thr Asn 
    50                  55                  60                  


Ile Ala Val Leu Lys His Asn Leu Asn Ile Leu Ile Lys Arg Ser Asn 
65                  70                  75                  80  


Ser Thr Ala Ala Thr Asn Glu Val Pro Glu Val Thr Val Phe Ser Lys 
                85                  90                  95      


Ser Pro Val Thr Leu Gly Gln Pro Asn Thr Leu Ile Cys Leu Val Asp 
            100                 105                 110         


Asn Ile Phe Pro Pro Val Val Asn Ile Thr Trp Leu Ser Asn Gly His 
        115                 120                 125             


Ser Val Thr Glu Gly Val Ser Glu Thr Ser Phe Leu Ser Lys Ser Asp 
    130                 135                 140                 


His Ser Phe Phe Lys Ile Ser Tyr Leu Thr Phe Leu Pro Ser Ala Asp 
145                 150                 155                 160 


Glu Ile Tyr Asp Cys Lys Val Glu His Trp Gly Leu Asp Glu Pro Leu 
                165                 170                 175     


Leu Lys His Trp Glu Pro Glu Ile Pro Ala Pro Met Ser Glu Leu Thr 
            180                 185                 190         


Glu 
    


<210>  560
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  560

Arg Asp Ser Pro Glu Asp Phe Val Tyr Gln Phe Lys Gly Met Cys Tyr 
1               5                   10                  15      


Phe Thr Asn Gly Thr Glu Arg Val Arg Leu Val Thr Arg Tyr Ile Tyr 
            20                  25                  30          


Asn Arg Glu Glu Tyr Ala Arg Phe Asp Ser Asp Val Gly Val Tyr Arg 
        35                  40                  45              


Ala Val Thr Pro Leu Gly Pro Pro Ala Ala Glu Tyr Trp Asn Ser Gln 
    50                  55                  60                  


Lys Glu Val Leu Glu Arg Thr Arg Ala Glu Leu Asp Thr Val Cys Arg 
65                  70                  75                  80  


His Asn Tyr Gln Leu Glu Leu Arg Thr Thr Leu Gln Arg Arg Val Glu 
                85                  90                  95      


Pro Thr Val Thr Ile Ser Pro Ser Arg Thr Glu Ala Leu Asn His His 
            100                 105                 110         


Asn Leu Leu Val Cys Ser Val Thr Asp Phe Tyr Pro Ala Gln Ile Lys 
        115                 120                 125             


Val Arg Trp Phe Arg Asn Asp Gln Glu Glu Thr Thr Gly Val Val Ser 
    130                 135                 140                 


Thr Pro Leu Ile Arg Asn Gly Asp Trp Thr Phe Gln Ile Leu Val Met 
145                 150                 155                 160 


Leu Glu Met Thr Pro Gln Arg Gly Asp Val Tyr Thr Cys His Val Glu 
                165                 170                 175     


His Pro Ser Leu Gln Asn Pro Ile Ile Val Glu Trp Arg Ala Gln Ser 
            180                 185                 190         


Glu Ser Ala Gln Ser Lys 
        195             


<210>  561
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  561

Ile Lys Glu Glu His Val Ile Ile Gln Ala Glu Phe Tyr Leu Asn Pro 
1               5                   10                  15      


Asp Gln Ser Gly Glu Phe Met Phe Asp Phe Asp Gly Asp Glu Ile Phe 
            20                  25                  30          


His Val Asp Met Ala Lys Lys Glu Thr Val Trp Arg Leu Glu Glu Phe 
        35                  40                  45              


Gly Arg Phe Ala Ser Phe Glu Ala Gln Gly Ala Leu Ala Asn Ile Ala 
    50                  55                  60                  


Val Asp Lys Ala Asn Leu Glu Ile Met Thr Lys Arg Ser Asn Tyr Thr 
65                  70                  75                  80  


Pro Ile Thr Asn Val Pro Pro Glu Val Thr Val Leu Thr Asn Ser Pro 
                85                  90                  95      


Val Glu Leu Arg Glu Pro Asn Val Leu Ile Cys Phe Ile Asp Lys Phe 
            100                 105                 110         


Thr Pro Pro Val Val Asn Val Thr Trp Leu Arg Asn Gly Lys Pro Val 
        115                 120                 125             


Thr Thr Gly Val Ser Glu Thr Val Phe Leu Pro Arg Glu Asp His Leu 
    130                 135                 140                 


Phe Arg Lys Phe His Tyr Leu Pro Phe Leu Pro Ser Thr Glu Asp Val 
145                 150                 155                 160 


Tyr Asp Cys Arg Val Glu His Trp Gly Leu Asp Glu Pro Leu Leu Lys 
                165                 170                 175     


His Trp Glu Phe Asp Ala Pro Ser Pro Leu Pro Glu Thr Thr Glu 
            180                 185                 190     


<210>  562
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  562

Gly Asp Thr Arg Pro Arg Phe Leu Trp Gln Pro Lys Arg Glu Cys His 
1               5                   10                  15      


Phe Phe Asn Gly Thr Glu Arg Val Arg Phe Leu Asp Arg Tyr Phe Tyr 
            20                  25                  30          


Asn Gln Glu Glu Ser Val Arg Phe Asp Ser Asp Val Gly Glu Phe Arg 
        35                  40                  45              


Ala Val Thr Glu Leu Gly Arg Pro Asp Ala Glu Tyr Trp Asn Ser Gln 
    50                  55                  60                  


Lys Asp Ile Leu Glu Gln Ala Arg Ala Ala Val Asp Thr Tyr Cys Arg 
65                  70                  75                  80  


His Asn Tyr Gly Val Gly Glu Ser Phe Ala Val Gln Arg Arg Val Gln 
                85                  90                  95      


Pro Lys Val Thr Val Tyr Pro Ser Lys Thr Gln Pro Leu Gln His His 
            100                 105                 110         


Asn Leu Leu Val Cys Ser Val Ser Gly Phe Tyr Pro Gly Ser Ile Glu 
        115                 120                 125             


Val Arg Trp Phe Leu Asn Gly Gln Glu Glu Lys Ala Gly Met Val Ser 
    130                 135                 140                 


Thr Gly Leu Ile Gln Asn Gly Asp Trp Thr Phe Gln Thr Leu Val Met 
145                 150                 155                 160 


Leu Glu Thr Val Pro Arg Ser Gly Glu Val Tyr Thr Cys Gln Val Glu 
                165                 170                 175     


His Pro Ser Val Thr Ser Pro Leu Thr Val Glu Trp Arg Ala Arg Ser 
            180                 185                 190         


Glu Ser Ala Gln Ser Lys 
        195             


<210>  563
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  563

Gly Ser His Ser Leu Lys Tyr Phe His Thr Ser Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ser Val Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Asn Asp Ala Ala Ser Pro Arg Met Val Pro Arg 
        35                  40                  45              


Ala Pro Trp Met Glu Gln Glu Gly Ser Glu Tyr Trp Asp Arg Glu Thr 
    50                  55                  60                  


Arg Ser Ala Arg Asp Thr Ala Gln Ile Phe Arg Val Asn Leu Arg Thr 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Leu Gln 
                85                  90                  95      


Trp Met His Gly Cys Glu Leu Gly Pro Asp Arg Arg Phe Leu Arg Gly 
            100                 105                 110         


Tyr Glu Gln Phe Ala Tyr Asp Gly Lys Asp Tyr Leu Thr Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Val Asp Thr Ala Ala Gln Ile Ser Glu 
    130                 135                 140                 


Gln Lys Ser Asn Asp Ala Ser Glu Ala Glu His Gln Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Asp Thr Cys Val Glu Trp Leu His Lys Tyr Leu Glu Lys Gly Lys 
                165                 170                 175     


Glu Thr Leu Leu His Leu Glu Pro Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Gln Asp Gly Glu Gly His 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Glu Pro Val Thr Leu 
            260                 265                 270         


Arg Trp Lys Pro Ala Ser Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  564
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  564

Gly Ser His Ser Leu Arg Tyr Phe Ser Thr Ala Val Ser Arg Pro Gly 
1               5                   10                  15      


Arg Gly Glu Pro Arg Tyr Ile Ala Val Glu Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Leu Arg Phe Asp Ser Asp Ala Ala Ile Pro Arg Met Glu Pro Arg 
        35                  40                  45              


Glu Pro Trp Val Glu Gln Glu Gly Pro Gln Tyr Trp Glu Trp Thr Thr 
    50                  55                  60                  


Gly Tyr Ala Lys Ala Asn Ala Gln Thr Asp Arg Val Ala Leu Arg Asn 
65                  70                  75                  80  


Leu Leu Arg Arg Tyr Asn Gln Ser Glu Ala Gly Ser His Thr Leu Gln 
                85                  90                  95      


Gly Met Asn Gly Cys Asp Met Gly Pro Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


Tyr His Gln His Ala Tyr Asp Gly Lys Asp Tyr Ile Ser Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Thr Val Ala Gln Ile Thr Gln 
    130                 135                 140                 


Arg Phe Tyr Glu Ala Glu Glu Tyr Ala Glu Glu Phe Arg Thr Tyr Leu 
145                 150                 155                 160 


Glu Gly Glu Cys Leu Glu Leu Leu Arg Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Thr Leu Gln Arg Ala Asp Pro Pro Lys Ala His Val Ala His His 
            180                 185                 190         


Pro Ile Ser Asp His Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Thr Leu Thr Trp Gln Arg Asp Gly Glu Glu Gln 
    210                 215                 220                 


Thr Gln Asp Thr Glu Leu Val Glu Thr Arg Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Gln Pro Leu Ile Leu 
            260                 265                 270         


Arg Trp Glu Gln Ser Pro Gln Pro Thr Ile Pro Ile 
        275                 280                 


<210>  565
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  565

Gly Ser His Ser Met Arg Tyr Phe Ser Ala Ala Val Ser Arg Pro Ser 
1               5                   10                  15      


Arg Gly Glu Pro Arg Phe Ile Ala Met Gly Tyr Val Asp Asp Thr Gln 
            20                  25                  30          


Phe Val Arg Phe Asp Ser Asp Ser Ala Cys Pro Arg Met Glu Pro Arg 
        35                  40                  45              


Ala Pro Trp Val Glu Arg Glu Gly Pro Glu Tyr Trp Glu Glu Glu Thr 
    50                  55                  60                  


Arg Asn Thr Lys Ala His Ala Gln Thr Asp Arg Met Asn Leu Gln Thr 
65                  70                  75                  80  


Leu Arg Gly Tyr Tyr Asn Gln Ser Glu Ala Ser Ser His Thr Leu Gln 
                85                  90                  95      


Trp Met Ile Gly Cys Asp Leu Gly Ser Asp Gly Arg Leu Leu Arg Gly 
            100                 105                 110         


Tyr Glu Gln Tyr Ala Tyr Asp Gly Lys Asp Tyr Leu Ala Leu Asn Glu 
        115                 120                 125             


Asp Leu Arg Ser Trp Thr Ala Ala Asp Thr Ala Ala Gln Ile Ser Lys 
    130                 135                 140                 


Arg Lys Cys Glu Ala Ala Asn Val Ala Glu Gln Arg Arg Ala Tyr Leu 
145                 150                 155                 160 


Glu Gly Thr Cys Val Glu Trp Leu His Arg Tyr Leu Glu Asn Gly Lys 
                165                 170                 175     


Glu Met Leu Gln Arg Ala Asp Pro Pro Lys Thr His Val Thr His His 
            180                 185                 190         


Pro Val Phe Asp Tyr Glu Ala Thr Leu Arg Cys Trp Ala Leu Gly Phe 
        195                 200                 205             


Tyr Pro Ala Glu Ile Ile Leu Thr Trp Gln Arg Asp Gly Glu Asp Gln 
    210                 215                 220                 


Thr Gln Asp Val Glu Leu Val Glu Thr Lys Pro Ala Gly Asp Gly Thr 
225                 230                 235                 240 


Phe Gln Lys Trp Ala Ala Val Val Val Pro Ser Gly Glu Glu Gln Arg 
                245                 250                 255     


Tyr Thr Cys His Val Gln His Glu Gly Leu Pro Glu Pro Leu Met Leu 
            260                 265                 270         


Arg Trp Lys Gln Ser Ser Leu Pro Thr Ile Pro Ile 
        275                 280                 


<210>  566
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  566

Gly Lys Gly Asp Pro Lys Lys Pro Arg Gly Lys Met Ser Ser Tyr Ala 
1               5                   10                  15      


Phe Phe Val Gln Thr Cys Arg Glu Glu His Lys Lys Lys His Pro Asp 
            20                  25                  30          


Ala Ser Val Asn Phe Ser Glu Phe Ser Lys Lys Cys Ser Glu Arg Trp 
        35                  40                  45              


Lys Thr Met Ser Ala Lys Glu Lys Gly Lys Phe Glu Asp Met Ala Lys 
    50                  55                  60                  


Ala Asp Lys Ala Arg Tyr Glu Arg Glu Met Lys Thr Tyr Ile Pro Pro 
65                  70                  75                  80  


Lys Gly Glu Thr Lys Lys Lys Phe Lys Asp Pro Asn Ala Pro Lys Arg 
                85                  90                  95      


Pro Pro Ser Ala Phe Phe Leu Phe Cys Ser Glu Tyr Arg Pro Lys Ile 
            100                 105                 110         


Lys Gly Glu His Pro Gly Leu Ser Ile Gly Asp Val Ala Lys Lys Leu 
        115                 120                 125             


Gly Glu Met Trp Asn Asn Thr Ala Ala Asp Asp Lys Gln Pro Tyr Glu 
    130                 135                 140                 


Lys Lys Ala Ala Lys Leu Lys Glu Lys Tyr Glu Lys Asp Ile Ala Ala 
145                 150                 155                 160 


Tyr Arg Ala Lys Gly Lys Pro Asp Ala Ala Lys Lys Gly Val Val Lys 
                165                 170                 175     


Ala Glu Lys Ser Lys Lys Lys Lys Glu Glu Glu Glu Asp Glu Glu Asp 
            180                 185                 190         


Glu Glu Asp Glu Glu Glu Glu Glu Asp Glu Glu Asp Glu Asp Glu Glu 
        195                 200                 205             


Glu Asp Asp Asp Asp Glu 
    210                 


<210>  567
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  567

Gly Lys Gly Asp Pro Asn Lys Pro Arg Gly Lys Met Ser Ser Tyr Ala 
1               5                   10                  15      


Phe Phe Val Gln Thr Cys Arg Glu Glu His Lys Lys Lys His Pro Asp 
            20                  25                  30          


Ser Ser Val Asn Phe Ala Glu Phe Ser Lys Lys Cys Ser Glu Arg Trp 
        35                  40                  45              


Lys Thr Met Ser Ala Lys Glu Lys Ser Lys Phe Glu Asp Met Ala Lys 
    50                  55                  60                  


Ser Asp Lys Ala Arg Tyr Asp Arg Glu Met Lys Asn Tyr Val Pro Pro 
65                  70                  75                  80  


Lys Gly Asp Lys Lys Gly Lys Lys Lys Asp Pro Asn Ala Pro Lys Arg 
                85                  90                  95      


Pro Pro Ser Ala Phe Phe Leu Phe Cys Ser Glu His Arg Pro Lys Ile 
            100                 105                 110         


Lys Ser Glu His Pro Gly Leu Ser Ile Gly Asp Thr Ala Lys Lys Leu 
        115                 120                 125             


Gly Glu Met Trp Ser Glu Gln Ser Ala Lys Asp Lys Gln Pro Tyr Glu 
    130                 135                 140                 


Gln Lys Ala Ala Lys Leu Lys Glu Lys Tyr Glu Lys Asp Ile Ala Ala 
145                 150                 155                 160 


Tyr Arg Ala Lys Gly Lys Ser Glu Ala Gly Lys Lys Gly Pro Gly Arg 
                165                 170                 175     


Pro Thr Gly Ser Lys Lys Lys Asn Glu Pro Glu Asp Glu Glu Glu Glu 
            180                 185                 190         


Glu Glu Glu Glu Asp Glu Asp Glu Glu Glu Glu Asp Glu Asp Glu Glu 
        195                 200                 205             


<210>  568
<211>  414
<212>  PRT
<213>  Homo Sapiens

<400>  568

Phe Arg Gly Pro Leu Leu Pro Asn Arg Pro Phe Thr Thr Val Trp Asn 
1               5                   10                  15      


Ala Asn Thr Gln Trp Cys Leu Glu Arg His Gly Val Asp Val Asp Val 
            20                  25                  30          


Ser Val Phe Asp Val Val Ala Asn Pro Gly Gln Thr Phe Arg Gly Pro 
        35                  40                  45              


Asp Met Thr Ile Phe Tyr Ser Ser Gln Leu Gly Thr Tyr Pro Tyr Tyr 
    50                  55                  60                  


Thr Pro Thr Gly Glu Pro Val Phe Gly Gly Leu Pro Gln Asn Ala Ser 
65                  70                  75                  80  


Leu Ile Ala His Leu Ala Arg Thr Phe Gln Asp Ile Leu Ala Ala Ile 
                85                  90                  95      


Pro Ala Pro Asp Phe Ser Gly Leu Ala Val Ile Asp Trp Glu Ala Trp 
            100                 105                 110         


Arg Pro Arg Trp Ala Phe Asn Trp Asp Thr Lys Asp Ile Tyr Arg Gln 
        115                 120                 125             


Arg Ser Arg Ala Leu Val Gln Ala Gln His Pro Asp Trp Pro Ala Pro 
    130                 135                 140                 


Gln Val Glu Ala Val Ala Gln Asp Gln Phe Gln Gly Ala Ala Arg Ala 
145                 150                 155                 160 


Trp Met Ala Gly Thr Leu Gln Leu Gly Arg Ala Leu Arg Pro Arg Gly 
                165                 170                 175     


Leu Trp Gly Phe Tyr Gly Phe Pro Asp Cys Tyr Asn Tyr Asp Phe Leu 
            180                 185                 190         


Ser Pro Asn Tyr Thr Gly Gln Cys Pro Ser Gly Ile Arg Ala Gln Asn 
        195                 200                 205             


Asp Gln Leu Gly Trp Leu Trp Gly Gln Ser Arg Ala Leu Tyr Pro Ser 
    210                 215                 220                 


Ile Tyr Met Pro Ala Val Leu Glu Gly Thr Gly Lys Ser Gln Met Tyr 
225                 230                 235                 240 


Val Gln His Arg Val Ala Glu Ala Phe Arg Val Ala Val Ala Ala Gly 
                245                 250                 255     


Asp Pro Asn Leu Pro Val Leu Pro Tyr Val Gln Ile Phe Tyr Asp Thr 
            260                 265                 270         


Thr Asn His Phe Leu Pro Leu Asp Glu Leu Glu His Ser Leu Gly Glu 
        275                 280                 285             


Ser Ala Ala Gln Gly Ala Ala Gly Val Val Leu Trp Val Ser Trp Glu 
    290                 295                 300                 


Asn Thr Arg Thr Lys Glu Ser Cys Gln Ala Ile Lys Glu Tyr Met Asp 
305                 310                 315                 320 


Thr Thr Leu Gly Pro Phe Ile Leu Asn Val Thr Ser Gly Ala Leu Leu 
                325                 330                 335     


Cys Ser Gln Ala Leu Cys Ser Gly His Gly Arg Cys Val Arg Arg Thr 
            340                 345                 350         


Ser His Pro Lys Ala Leu Leu Leu Leu Asn Pro Ala Ser Phe Ser Ile 
        355                 360                 365             


Gln Leu Thr Pro Gly Gly Gly Pro Leu Ser Leu Arg Gly Ala Leu Ser 
    370                 375                 380                 


Leu Glu Asp Gln Ala Gln Met Ala Val Glu Phe Lys Cys Arg Cys Tyr 
385                 390                 395                 400 


Pro Gly Trp Gln Ala Pro Trp Cys Glu Arg Lys Ser Met Trp 
                405                 410                 


<210>  569
<211>  428
<212>  PRT
<213>  Homo Sapiens

<400>  569

Met Glu Leu Lys Pro Thr Ala Pro Pro Ile Phe Thr Gly Arg Pro Phe 
1               5                   10                  15      


Val Val Ala Trp Asp Val Pro Thr Gln Asp Cys Gly Pro Arg Leu Lys 
            20                  25                  30          


Val Pro Leu Asp Leu Asn Ala Phe Asp Val Gln Ala Ser Pro Asn Glu 
        35                  40                  45              


Gly Phe Val Asn Gln Asn Ile Thr Ile Phe Tyr Arg Asp Arg Leu Gly 
    50                  55                  60                  


Leu Tyr Pro Arg Phe Asp Ser Ala Gly Arg Ser Val His Gly Gly Val 
65                  70                  75                  80  


Pro Gln Asn Val Ser Leu Trp Ala His Arg Lys Met Leu Gln Lys Arg 
                85                  90                  95      


Val Glu His Tyr Ile Arg Thr Gln Glu Ser Ala Gly Leu Ala Val Ile 
            100                 105                 110         


Asp Trp Glu Asp Trp Arg Pro Val Trp Val Arg Asn Trp Gln Asp Lys 
        115                 120                 125             


Asp Val Tyr Arg Arg Leu Ser Arg Gln Leu Val Ala Ser Arg His Pro 
    130                 135                 140                 


Asp Trp Pro Pro Asp Arg Ile Val Lys Gln Ala Gln Tyr Glu Phe Glu 
145                 150                 155                 160 


Phe Ala Ala Gln Gln Phe Met Leu Glu Thr Leu Arg Tyr Val Lys Ala 
                165                 170                 175     


Val Arg Pro Arg His Leu Trp Gly Phe Tyr Leu Phe Pro Asp Cys Tyr 
            180                 185                 190         


Asn His Asp Tyr Val Gln Asn Trp Glu Ser Tyr Thr Gly Arg Cys Pro 
        195                 200                 205             


Asp Val Glu Val Ala Arg Asn Asp Gln Leu Ala Trp Leu Trp Ala Glu 
    210                 215                 220                 


Ser Thr Ala Leu Phe Pro Ser Val Tyr Leu Asp Glu Thr Leu Ala Ser 
225                 230                 235                 240 


Ser Arg His Gly Arg Asn Phe Val Ser Phe Arg Val Gln Glu Ala Leu 
                245                 250                 255     


Arg Val Ala Arg Thr His His Ala Asn His Ala Leu Pro Val Tyr Val 
            260                 265                 270         


Phe Thr Arg Pro Thr Tyr Ser Arg Arg Leu Thr Gly Leu Ser Glu Met 
        275                 280                 285             


Asp Leu Ile Ser Thr Ile Gly Glu Ser Ala Ala Leu Gly Ala Ala Gly 
    290                 295                 300                 


Val Ile Leu Trp Gly Asp Ala Gly Tyr Thr Thr Ser Thr Glu Thr Cys 
305                 310                 315                 320 


Gln Tyr Leu Lys Asp Tyr Leu Thr Arg Leu Leu Val Pro Tyr Val Val 
                325                 330                 335     


Asn Val Ser Trp Ala Thr Gln Tyr Cys Ser Arg Ala Gln Cys His Gly 
            340                 345                 350         


His Gly Arg Cys Val Arg Arg Asn Pro Ser Ala Ser Thr Phe Leu His 
        355                 360                 365             


Leu Ser Thr Asn Ser Phe Arg Leu Val Pro Gly His Ala Pro Gly Glu 
    370                 375                 380                 


Pro Gln Leu Arg Pro Val Gly Glu Leu Ser Trp Ala Asp Ile Asp His 
385                 390                 395                 400 


Leu Gln Thr His Phe Arg Cys Gln Cys Tyr Leu Gly Trp Ser Gly Glu 
                405                 410                 415     


Gln Cys Gln Trp Asp His Arg Gln Ala Ala Gly Gly 
            420                 425             


<210>  570
<211>  397
<212>  PRT
<213>  Homo Sapiens

<400>  570

Gln Pro Leu Pro Gln Val Pro Glu Arg Pro Phe Ser Val Leu Trp Asn 
1               5                   10                  15      


Val Pro Ser Ala His Cys Glu Ala Arg Phe Gly Val His Leu Pro Leu 
            20                  25                  30          


Asn Ser Leu Gly Ile Ile Ala Asn Arg Gly Gln His Phe His Gly Gln 
        35                  40                  45              


Asn Met Thr Ile Phe Tyr Lys Asn Gln Leu Gly Leu Tyr Pro Tyr Phe 
    50                  55                  60                  


Gly Pro Arg Gly Thr Ala His Asn Gly Gly Ile Pro Gln Ala Leu Pro 
65                  70                  75                  80  


Leu Asp Arg His Leu Ala Leu Ala Ala Tyr Gln Ile His His Ser Leu 
                85                  90                  95      


Arg Pro Gly Phe Ala Gly Pro Ala Val Leu Asp Trp Glu Glu Trp Cys 
            100                 105                 110         


Pro Leu Trp Ala Gly Asn Trp Gly Arg Arg Arg Ala Tyr Gln Ala Ala 
        115                 120                 125             


Ser Trp Ala Trp Ala Gln Gln Val Phe Pro Asp Leu Asp Pro Gln Glu 
    130                 135                 140                 


Gln Leu Tyr Lys Ala Tyr Thr Gly Phe Glu Gln Ala Ala Arg Ala Leu 
145                 150                 155                 160 


Met Glu Asp Thr Leu Arg Val Ala Gln Ala Leu Arg Pro His Gly Leu 
                165                 170                 175     


Trp Gly Phe Tyr His Tyr Pro Ala Cys Gly Asn Gly Trp His Ser Met 
            180                 185                 190         


Ala Ser Asn Tyr Thr Gly Arg Cys His Ala Ala Thr Leu Ala Arg Asn 
        195                 200                 205             


Thr Gln Leu His Trp Leu Trp Ala Ala Ser Ser Ala Leu Phe Pro Ser 
    210                 215                 220                 


Ile Tyr Leu Pro Pro Arg Leu Pro Pro Ala His His Gln Ala Phe Val 
225                 230                 235                 240 


Arg His Arg Leu Glu Glu Ala Phe Arg Val Ala Leu Val Gly His Arg 
                245                 250                 255     


His Pro Leu Pro Val Leu Ala Tyr Val Arg Leu Thr His Arg Arg Ser 
            260                 265                 270         


Gly Arg Phe Leu Ser Gln Asp Asp Leu Val Gln Ser Ile Gly Val Ser 
        275                 280                 285             


Ala Ala Leu Gly Ala Ala Gly Val Val Leu Trp Gly Asp Leu Ser Leu 
    290                 295                 300                 


Ser Ser Ser Glu Glu Glu Cys Trp His Leu His Asp Tyr Leu Val Asp 
305                 310                 315                 320 


Thr Leu Gly Pro Tyr Val Ile Asn Val Thr Arg Ala Ala Met Ala Cys 
                325                 330                 335     


Ser His Gln Arg Cys His Gly His Gly Arg Cys Ala Arg Arg Asp Pro 
            340                 345                 350         


Gly Gln Met Glu Ala Phe Leu His Leu Trp Pro Asp Gly Ser Leu Gly 
        355                 360                 365             


Asp Trp Lys Ser Phe Ser Cys His Cys Tyr Trp Gly Trp Ala Gly Pro 
    370                 375                 380                 


Thr Cys Gln Glu Pro Arg Pro Gly Pro Lys Glu Ala Val 
385                 390                 395         


<210>  571
<211>  453
<212>  PRT
<213>  Homo Sapiens

<400>  571

Gln Thr Ser Val Ser Pro Ser Lys Val Ile Leu Pro Arg Gly Gly Ser 
1               5                   10                  15      


Val Leu Val Thr Cys Ser Thr Ser Cys Asp Gln Pro Lys Leu Leu Gly 
            20                  25                  30          


Ile Glu Thr Pro Leu Pro Lys Lys Glu Leu Leu Leu Pro Gly Asn Asn 
        35                  40                  45              


Arg Lys Val Tyr Glu Leu Ser Asn Val Gln Glu Asp Ser Gln Pro Met 
    50                  55                  60                  


Cys Tyr Ser Asn Cys Pro Asp Gly Gln Ser Thr Ala Lys Thr Phe Leu 
65                  70                  75                  80  


Thr Val Tyr Trp Thr Pro Glu Arg Val Glu Leu Ala Pro Leu Pro Ser 
                85                  90                  95      


Trp Gln Pro Val Gly Lys Asn Leu Thr Leu Arg Cys Gln Val Glu Gly 
            100                 105                 110         


Gly Ala Pro Arg Ala Asn Leu Thr Val Val Leu Leu Arg Gly Glu Lys 
        115                 120                 125             


Glu Leu Lys Arg Glu Pro Ala Val Gly Glu Pro Ala Glu Val Thr Thr 
    130                 135                 140                 


Thr Val Leu Val Arg Arg Asp His His Gly Ala Asn Phe Ser Cys Arg 
145                 150                 155                 160 


Thr Glu Leu Asp Leu Arg Pro Gln Gly Leu Glu Leu Phe Glu Asn Thr 
                165                 170                 175     


Ser Ala Pro Tyr Gln Leu Gln Thr Phe Val Leu Pro Ala Thr Pro Pro 
            180                 185                 190         


Gln Leu Val Ser Pro Arg Val Leu Glu Val Asp Thr Gln Gly Thr Val 
        195                 200                 205             


Val Cys Ser Leu Asp Gly Leu Phe Pro Val Ser Glu Ala Gln Val His 
    210                 215                 220                 


Leu Ala Leu Gly Asp Gln Arg Leu Asn Pro Thr Val Thr Tyr Gly Asn 
225                 230                 235                 240 


Asp Ser Phe Ser Ala Lys Ala Ser Val Ser Val Thr Ala Glu Asp Glu 
                245                 250                 255     


Gly Thr Gln Arg Leu Thr Cys Ala Val Ile Leu Gly Asn Gln Ser Gln 
            260                 265                 270         


Glu Thr Leu Gln Thr Val Thr Ile Tyr Ser Phe Pro Ala Pro Asn Val 
        275                 280                 285             


Ile Leu Thr Lys Pro Glu Val Ser Glu Gly Thr Glu Val Thr Val Lys 
    290                 295                 300                 


Cys Glu Ala His Pro Arg Ala Lys Val Thr Leu Asn Gly Val Pro Ala 
305                 310                 315                 320 


Gln Pro Leu Gly Pro Arg Ala Gln Leu Leu Leu Lys Ala Thr Pro Glu 
                325                 330                 335     


Asp Asn Gly Arg Ser Phe Ser Cys Ser Ala Thr Leu Glu Val Ala Gly 
            340                 345                 350         


Gln Leu Ile His Lys Asn Gln Thr Arg Glu Leu Arg Val Leu Tyr Gly 
        355                 360                 365             


Pro Arg Leu Asp Glu Arg Asp Cys Pro Gly Asn Trp Thr Trp Pro Glu 
    370                 375                 380                 


Asn Ser Gln Gln Thr Pro Met Cys Gln Ala Trp Gly Asn Pro Leu Pro 
385                 390                 395                 400 


Glu Leu Lys Cys Leu Lys Asp Gly Thr Phe Pro Leu Pro Ile Gly Glu 
                405                 410                 415     


Ser Val Thr Val Thr Arg Asp Leu Glu Gly Thr Tyr Leu Cys Arg Ala 
            420                 425                 430         


Arg Ser Thr Gln Gly Glu Val Thr Arg Lys Val Thr Val Asn Val Leu 
        435                 440                 445             


Ser Pro Arg Tyr Glu 
    450             


<210>  572
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  572

Lys Val Phe Glu Val His Val Arg Pro Lys Lys Leu Ala Val Glu Pro 
1               5                   10                  15      


Lys Gly Ser Leu Glu Val Asn Cys Ser Thr Thr Cys Asn Gln Pro Glu 
            20                  25                  30          


Val Gly Gly Leu Glu Thr Ser Leu Asp Lys Ile Leu Leu Asp Glu Gln 
        35                  40                  45              


Ala Gln Trp Lys His Tyr Leu Val Ser Asn Ile Ser His Asp Thr Val 
    50                  55                  60                  


Leu Gln Cys His Phe Thr Cys Ser Gly Lys Gln Glu Ser Met Asn Ser 
65                  70                  75                  80  


Asn Val Ser Val Tyr Gln Pro Pro Arg Gln Val Ile Leu Thr Leu Gln 
                85                  90                  95      


Pro Thr Leu Val Ala Val Gly Lys Ser Phe Thr Ile Glu Cys Arg Val 
            100                 105                 110         


Pro Thr Val Glu Pro Leu Asp Ser Leu Thr Leu Phe Leu Phe Arg Gly 
        115                 120                 125             


Asn Glu Thr Leu His Tyr Glu Thr Phe Gly Lys Ala Ala Pro Ala Pro 
    130                 135                 140                 


Gln Glu Ala Thr Ala Thr Phe Asn Ser Thr Ala Asp Arg Glu Asp Gly 
145                 150                 155                 160 


His Arg Asn Phe Ser Cys Leu Ala Val Leu Asp Leu Met Ser Arg Gly 
                165                 170                 175     


Gly Asn Ile Phe His Lys His Ser Ala Pro Lys Met Leu Glu Ile Tyr 
            180                 185                 190         


Glu Pro Val Ser Asp Ser Gln 
        195                 


<210>  573
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  573

Gln Glu Phe Leu Leu Arg Val Glu Pro Gln Asn Pro Val Leu Ser Ala 
1               5                   10                  15      


Gly Gly Ser Leu Phe Val Asn Cys Ser Thr Asp Cys Pro Ser Ser Glu 
            20                  25                  30          


Lys Ile Ala Leu Glu Thr Ser Leu Ser Lys Glu Leu Val Ala Ser Gly 
        35                  40                  45              


Met Gly Trp Ala Ala Phe Asn Leu Ser Asn Val Thr Gly Asn Ser Arg 
    50                  55                  60                  


Ile Leu Cys Ser Val Tyr Cys Asn Gly Ser Gln Ile Thr Gly Ser Ser 
65                  70                  75                  80  


Asn Ile Thr Val Tyr Arg Leu Pro Glu Arg Val Glu Leu Ala Pro Leu 
                85                  90                  95      


Pro Pro Trp Gln Pro Val Gly Gln Asn Phe Thr Leu Arg Cys Gln Val 
            100                 105                 110         


Glu Asp Gly Ser Pro Arg Thr Ser Leu Thr Val Val Leu Leu Arg Trp 
        115                 120                 125             


Glu Glu Glu Leu Ser Arg Gln Pro Ala Val Glu Glu Pro Ala Glu Val 
    130                 135                 140                 


Thr Ala Thr Val Leu Ala Ser Arg Asp Asp His Gly Ala Pro Phe Ser 
145                 150                 155                 160 


Cys Arg Thr Glu Leu Asp Met Gln Pro Gln Gly Leu Gly Leu Phe Val 
                165                 170                 175     


Asn Thr Ser Ala Pro Arg Gln Leu Arg Thr Phe Val Leu Pro Val Thr 
            180                 185                 190         


Pro Pro Arg Leu Val Ala Pro Arg Phe Leu Glu Val Glu Thr Ser Trp 
        195                 200                 205             


Pro Val Asp Cys Thr Leu Asp Gly Leu Phe Pro Ala Ser Glu Ala Gln 
    210                 215                 220                 


Val Tyr Leu Ala Leu Gly Asp Gln Met Leu Asn Ala Thr Val Met Asn 
225                 230                 235                 240 


His Gly Asp Thr Leu Thr Ala Thr Ala Thr Ala Thr Ala Arg Ala Asp 
                245                 250                 255     


Gln Glu Gly Ala Arg Glu Ile Val Cys Asn Val Thr Leu Gly Gly Glu 
            260                 265                 270         


Arg Arg Glu Ala Arg Glu Asn Leu Thr Val Phe Ser Phe Leu Gly Pro 
        275                 280                 285             


Ile Val Asn Leu Ser Glu Pro Thr Ala His Glu Gly Ser Thr Val Thr 
    290                 295                 300                 


Val Ser Cys Met Ala Gly Ala Arg Val Gln Val Thr Leu Asp Gly Val 
305                 310                 315                 320 


Pro Ala Ala Ala Pro Gly Gln Pro Ala Gln Leu Gln Leu Asn Ala Thr 
                325                 330                 335     


Glu Ser Asp Asp Gly Arg Ser Phe Phe Cys Ser Ala Thr Leu Glu Val 
            340                 345                 350         


Asp Gly Glu Phe Leu His Arg Asn Ser Ser Val Gln Leu Arg Val Leu 
        355                 360                 365             


Tyr Gly Pro Lys Ile Asp Arg Ala Thr Cys Pro Gln His Leu Lys Trp 
    370                 375                 380                 


Lys Asp Lys Thr Arg His Val Leu Gln Cys Gln Ala Arg Gly Asn Pro 
385                 390                 395                 400 


Tyr Pro Glu Leu Arg Cys Leu Lys Glu Gly Ser Ser Arg Glu Val Pro 
                405                 410                 415     


Val Gly Ile Pro Phe Phe Val Asn Val Thr His Asn Gly Thr Tyr Gln 
            420                 425                 430         


Cys Gln Ala Ser Ser Ser Arg Gly Lys Tyr Thr Leu Val Val Val Met 
        435                 440                 445             


Asp Ile Glu Ala Gly Ser Ser His 
    450                 455     


<210>  574
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  574

Ala Leu Gly Arg Arg Thr Lys Arg Ala Gln Ser Pro Lys Gly Ser Pro 
1               5                   10                  15      


Leu Ala Pro Ser Gly Thr Ser Val Pro Phe Trp Val Arg Met Ser Pro 
            20                  25                  30          


Glu Phe Val Ala Val Gln Pro Gly Lys Ser Val Gln Leu Asn Cys Ser 
        35                  40                  45              


Asn Ser Cys Pro Gln Pro Gln Asn Ser Ser Leu Arg Thr Pro Leu Arg 
    50                  55                  60                  


Gln Gly Lys Thr Leu Arg Gly Pro Gly Trp Val Ser Tyr Gln Leu Leu 
65                  70                  75                  80  


Asp Val Arg Ala Trp Ser Ser Leu Ala His Cys Leu Val Thr Cys Ala 
                85                  90                  95      


Gly Lys Thr Arg Trp Ala Thr Ser Arg Ile Thr Ala Tyr Ser Val Pro 
            100                 105                 110         


Gly Gly Leu Leu Gly Gly Asp Pro Glu Ala Trp Lys Pro Gly His Leu 
        115                 120                 125             


Phe Arg Lys Pro Gly Ala Leu His Arg Pro Gly Ser Gly Gln Arg Asp 
    130                 135                 140                 


Leu Asp Leu Arg Val Cys Cys Trp Thr Pro Arg Leu Leu Ala Ala Arg 
145                 150                 155                 160 


Asp Leu Pro Arg Ala Pro Gln Ser Arg Arg Pro Gly Gly Pro Gln Gln 
                165                 170                 175     


Leu Gly Thr His Tyr Thr Asp Ala Arg Leu Glu Pro Arg Ala His Ser 
            180                 185                 190         


Phe Gly Leu Arg Phe His Arg Cys Pro Cys Arg Asp Pro Pro His Cys 
        195                 200                 205             


Gly Arg Cys Val Pro Met Gln Val Pro Ser Tyr Glu Val Pro Gly Val 
    210                 215                 220                 


Lys Gly Asp Val Leu Cys Arg Leu Ser Glu Lys Lys Arg Asn Met Lys 
225                 230                 235                 240 


Gln Ser Gly Glu Met Ala Ile His Gly Gly 
                245                 250 


<210>  575
<211>  804
<212>  PRT
<213>  Homo Sapiens

<400>  575

Glu Pro Phe Trp Ala Asp Leu Gln Pro Arg Val Ala Phe Val Glu Arg 
1               5                   10                  15      


Gly Gly Ser Leu Trp Leu Asn Cys Ser Thr Asn Cys Pro Arg Pro Glu 
            20                  25                  30          


Arg Gly Gly Leu Glu Thr Ser Leu Arg Arg Asn Gly Thr Gln Arg Gly 
        35                  40                  45              


Leu Arg Trp Leu Ala Arg Gln Leu Val Asp Ile Arg Glu Pro Glu Thr 
    50                  55                  60                  


Gln Pro Val Cys Phe Phe Arg Cys Ala Arg Arg Thr Leu Gln Ala Arg 
65                  70                  75                  80  


Gly Leu Ile Arg Thr Phe Gln Arg Pro Asp Arg Val Glu Leu Met Pro 
                85                  90                  95      


Leu Pro Pro Trp Gln Pro Val Gly Glu Asn Phe Thr Leu Ser Cys Arg 
            100                 105                 110         


Val Pro Gly Ala Gly Pro Arg Ala Ser Leu Thr Leu Thr Leu Leu Arg 
        115                 120                 125             


Gly Ala Gln Glu Leu Ile Arg Arg Ser Phe Ala Gly Glu Pro Pro Arg 
    130                 135                 140                 


Ala Arg Gly Ala Val Leu Thr Ala Thr Val Leu Ala Arg Arg Glu Asp 
145                 150                 155                 160 


His Gly Ala Asn Phe Ser Cys Arg Ala Glu Leu Asp Leu Arg Pro His 
                165                 170                 175     


Gly Leu Gly Leu Phe Glu Asn Ser Ser Ala Pro Arg Glu Leu Arg Thr 
            180                 185                 190         


Phe Ser Leu Ser Pro Asp Ala Pro Arg Leu Ala Ala Pro Arg Leu Leu 
        195                 200                 205             


Glu Val Gly Ser Glu Arg Pro Val Ser Cys Thr Leu Asp Gly Leu Phe 
    210                 215                 220                 


Pro Ala Ser Glu Ala Arg Val Tyr Leu Ala Leu Gly Asp Gln Asn Leu 
225                 230                 235                 240 


Ser Pro Asp Val Thr Leu Glu Gly Asp Ala Phe Val Ala Thr Ala Thr 
                245                 250                 255     


Ala Thr Ala Ser Ala Glu Gln Glu Gly Ala Arg Gln Leu Ile Cys Asn 
            260                 265                 270         


Val Thr Leu Gly Gly Glu Asn Arg Glu Thr Arg Glu Asn Val Thr Ile 
        275                 280                 285             


Tyr Ser Phe Pro Ala Pro Leu Leu Thr Leu Ser Glu Pro Ser Val Ser 
    290                 295                 300                 


Glu Gly Gln Met Val Thr Val Thr Cys Ala Ala Gly Thr Gln Ala Leu 
305                 310                 315                 320 


Val Thr Leu Glu Gly Val Pro Ala Ala Val Pro Gly Gln Pro Ala Gln 
                325                 330                 335     


Leu Gln Leu Asn Ala Thr Glu Asn Asp Asp Arg Arg Ser Phe Phe Cys 
            340                 345                 350         


Asp Ala Thr Leu Asp Val Asp Gly Glu Thr Leu Ile Lys Asn Arg Ser 
        355                 360                 365             


Ala Glu Leu Arg Val Leu Tyr Ala Pro Arg Leu Asp Asp Ser Asp Cys 
    370                 375                 380                 


Pro Arg Ser Trp Thr Trp Pro Glu Gly Pro Glu Gln Thr Leu Arg Cys 
385                 390                 395                 400 


Glu Ala Arg Gly Asn Pro Glu Pro Ser Val His Cys Ala Arg Ser Asp 
                405                 410                 415     


Gly Gly Ala Val Leu Ala Leu Gly Leu Leu Gly Pro Val Thr Arg Ala 
            420                 425                 430         


Leu Ser Gly Thr Tyr Arg Cys Lys Ala Ala Asn Asp Gln Gly Glu Ala 
        435                 440                 445             


Val Lys Asp Val Thr Leu Thr Val Glu Tyr Ala Pro Ala Leu Asp Ser 
    450                 455                 460                 


Val Gly Cys Pro Glu Arg Ile Thr Trp Leu Glu Gly Thr Glu Ala Ser 
465                 470                 475                 480 


Leu Ser Cys Val Ala His Gly Val Pro Pro Pro Asp Val Ile Cys Val 
                485                 490                 495     


Arg Ser Gly Glu Leu Gly Ala Val Ile Glu Gly Leu Leu Arg Val Ala 
            500                 505                 510         


Arg Glu His Ala Gly Thr Tyr Arg Cys Glu Ala Thr Asn Pro Arg Gly 
        515                 520                 525             


Ser Ala Ala Lys Asn Val Ala Val Thr Val Glu Tyr Gly Pro Arg Phe 
    530                 535                 540                 


Glu Glu Pro Ser Cys Pro Ser Asn Trp Thr Trp Val Glu Gly Ser Gly 
545                 550                 555                 560 


Arg Leu Phe Ser Cys Glu Val Asp Gly Lys Pro Gln Pro Ser Val Lys 
                565                 570                 575     


Cys Val Gly Ser Gly Gly Ala Thr Glu Gly Val Leu Leu Pro Leu Ala 
            580                 585                 590         


Pro Pro Asp Pro Ser Pro Arg Ala Pro Arg Ile Pro Arg Val Leu Ala 
        595                 600                 605             


Pro Gly Ile Tyr Val Cys Asn Ala Thr Asn Arg His Gly Ser Val Ala 
    610                 615                 620                 


Lys Thr Val Val Val Ser Ala Glu Ser Pro Pro Glu Met Asp Glu Ser 
625                 630                 635                 640 


Thr Cys Pro Ser His Gln Thr Trp Leu Glu Gly Ala Glu Ala Ser Ala 
                645                 650                 655     


Leu Ala Cys Ala Ala Arg Gly Arg Pro Ser Pro Gly Val Arg Cys Ser 
            660                 665                 670         


Arg Glu Gly Ile Pro Trp Pro Glu Gln Gln Arg Val Ser Arg Glu Asp 
        675                 680                 685             


Ala Gly Thr Tyr His Cys Val Ala Thr Asn Ala His Gly Thr Asp Ser 
    690                 695                 700                 


Arg Thr Val Thr Val Gly Val Glu Tyr Arg Pro Val Val Ala Glu Leu 
705                 710                 715                 720 


Ala Ala Ser Pro Pro Gly Gly Val Arg Pro Gly Gly Asn Phe Thr Leu 
                725                 730                 735     


Thr Cys Arg Ala Glu Ala Trp Pro Pro Ala Gln Ile Ser Trp Arg Ala 
            740                 745                 750         


Pro Pro Gly Ala Leu Asn Ile Gly Leu Ser Ser Asn Asn Ser Thr Leu 
        755                 760                 765             


Ser Val Ala Gly Ala Met Gly Ser His Gly Gly Glu Tyr Glu Cys Ala 
    770                 775                 780                 


Ala Thr Asn Ala His Gly Arg His Ala Arg Arg Ile Thr Val Arg Val 
785                 790                 795                 800 


Ala Gly Pro Trp 
                


<210>  576
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  576

Glu Ile Asn Gly Ser Ala Asn Tyr Glu Met Phe Ile Phe His Asn Gly 
1               5                   10                  15      


Gly Val Gln Ile Leu Cys Lys Tyr Pro Asp Ile Val Gln Gln Phe Lys 
            20                  25                  30          


Met Gln Leu Leu Lys Gly Gly Gln Ile Leu Cys Asp Leu Thr Lys Thr 
        35                  40                  45              


Lys Gly Ser Gly Asn Thr Val Ser Ile Lys Ser Leu Lys Phe Cys His 
    50                  55                  60                  


Ser Gln Leu Ser Asn Asn Ser Val Ser Phe Phe Leu Tyr Asn Leu Asp 
65                  70                  75                  80  


His Ser His Ala Asn Tyr Tyr Phe Cys Asn Leu Ser Ile Phe Asp Pro 
                85                  90                  95      


Pro Pro Phe Lys Val Thr Leu Thr Gly Gly Tyr Leu His Ile Tyr Glu 
            100                 105                 110         


Ser Gln Leu Cys Cys Gln Leu Lys 
        115                 120 


<210>  577
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  577

Asp Thr Gln Glu Lys Glu Val Arg Ala Met Val Gly Ser Asp Val Glu 
1               5                   10                  15      


Leu Ser Cys Ala Cys Pro Glu Gly Ser Arg Phe Asp Leu Asn Asp Val 
            20                  25                  30          


Tyr Val Tyr Trp Gln Thr Ser Glu Ser Lys Thr Val Val Thr Tyr His 
        35                  40                  45              


Ile Pro Gln Asn Ser Ser Leu Glu Asn Val Asp Ser Arg Tyr Arg Asn 
    50                  55                  60                  


Arg Ala Leu Met Ser Pro Ala Gly Met Leu Arg Gly Asp Phe Ser Leu 
65                  70                  75                  80  


Arg Leu Phe Asn Val Thr Pro Gln Asp Glu Gln Lys Phe His Cys Leu 
                85                  90                  95      


Val Leu Ser Gln Ser Leu Gly Phe Gln Glu Val Leu Ser Val Glu Val 
            100                 105                 110         


Thr Leu His Val Ala Ala Asn Phe Ser Val Pro Val Val Ser Ala Pro 
        115                 120                 125             


His Ser Pro Ser Gln Asp Glu Leu Thr Phe Thr Cys Thr Ser Ile Asn 
    130                 135                 140                 


Gly Tyr Pro Arg Pro Asn Val Tyr Trp Ile Asn Lys Thr Asp Asn Ser 
145                 150                 155                 160 


Leu Leu Asp Gln Ala Leu Gln Asn Asp Thr Val Phe Leu Asn Met Arg 
                165                 170                 175     


Gly Leu Tyr Asp Val Val Ser Val Leu Arg Ile Ala Arg Thr Pro Ser 
            180                 185                 190         


Val Asn Ile Gly Cys Cys Ile Glu Asn Val Leu Leu Gln Gln Asn Leu 
        195                 200                 205             


Thr Val Gly Ser Gln Thr Gly Asn Asp Ile Gly Glu Arg Asp Lys Ile 
    210                 215                 220                 


Thr Glu Asn Pro Val Ser Thr Gly Glu Lys Asn Ala Ala Thr 
225                 230                 235             


<210>  578
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  578

Met Arg Glu Gly Lys Arg Gly Pro Pro Cys Ile Leu Ser Phe Arg Gly 
1               5                   10                  15      


Thr Leu Glu Arg Val Glu Ala Gln Trp Glu Leu Glu Ala Gln Gly Pro 
            20                  25                  30          


Gly Gln Cys Pro Ala Pro Leu Gly Asp Pro Ala Ser Thr Thr Asp Gly 
        35                  40                  45              


Ala Gln Glu Ala Arg Val Pro Leu Asp Gly Ala Phe Trp Ile Pro Arg 
    50                  55                  60                  


Pro Pro Ala Gly Ser Pro Lys Gly Cys Phe Ala Cys Val Ser Lys Pro 
65                  70                  75                  80  


Pro Ala Leu Gln Ala Pro Ala Ala Pro Ala Pro Glu Pro Ser Ala Ser 
                85                  90                  95      


Pro Pro Met Ala Pro Thr Leu Phe Pro Met Glu Ser Lys Ser Ser Lys 
            100                 105                 110         


Thr Asp Ser Val Arg Ala Ala Gly Ala Pro Pro Ala Cys Lys His Leu 
        115                 120                 125             


Ala Glu Lys Lys Thr Met Thr Asn Pro Thr Thr Val Ile Glu Val Tyr 
    130                 135                 140                 


Pro Asp Thr Thr Glu Val Asn Asp Tyr Tyr 
145                 150                 


<210>  579
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  579

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Gly Gln Met Gly Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Arg Ile Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Glu Asp Ser Ser Ala Ala Trp Glu Gln Ser 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Ser Thr Glu Leu Tyr Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Val Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Ile Glu Arg Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Asp 
                165     


<210>  580
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  580

Cys Asp Leu Pro Glu Thr His Ser Leu Asp Asn Arg Arg Thr Leu Met 
1               5                   10                  15      


Leu Leu Ala Gln Met Ser Arg Ile Ser Pro Ser Ser Cys Leu Met Asp 
            20                  25                  30          


Arg His Asp Phe Gly Phe Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Pro Ala Ile Ser Val Leu His Glu Leu Ile Gln Gln Ile 
    50                  55                  60                  


Phe Asn Leu Phe Thr Thr Lys Asp Ser Ser Ala Ala Trp Asp Glu Asp 
65                  70                  75                  80  


Leu Leu Asp Lys Phe Cys Thr Glu Leu Tyr Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Met Gln Glu Glu Arg Val Gly Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Ala Asp Ser Ile Leu Ala Val Lys Lys Tyr Phe Arg Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Leu Ser Thr Asn Leu Gln Glu 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Glu 
                165     


<210>  581
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  581

Cys Asn Leu Ser Gln Thr His Ser Leu Asn Asn Arg Arg Thr Leu Met 
1               5                   10                  15      


Leu Met Ala Gln Met Arg Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Glu Phe Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Met Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Lys Asn Ser Ser Ala Ala Trp Asp Glu Thr 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Tyr Ile Glu Leu Phe Gln Gln Met Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Val Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Lys Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Met Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Asp 
                165     


<210>  582
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  582

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Gly Arg Ile Ser His Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg Tyr Asp Phe Gly Phe Pro Gln Glu Val Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Ala Phe His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Lys Asp Ser Ser Ala Ala Trp Asp Glu Thr 
65                  70                  75                  80  


Leu Leu Asp Lys Phe Tyr Ile Glu Leu Phe Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Thr Gln Glu Val Gly Val Glu Glu Ile Ala Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Met Gly Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Phe Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Gly Leu Arg Arg Lys Asp 
                165     


<210>  583
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  583

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Gly Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Leu Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Thr Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Glu Asp Ser Ser Ala Ala Trp Glu Gln Ser 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Ser Thr Glu Leu Tyr Gln Gln Leu Asn Asn Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Met Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Ile Leu Arg Arg Lys Asp 
                165     


<210>  584
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  584

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Gly Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Leu Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Thr Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Glu Asp Ser Ser Ala Ala Trp Glu Gln Ser 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Ser Thr Glu Leu Tyr Gln Gln Leu Asn Asn Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Met Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Ile Leu Arg Arg Lys Asp 
                165     


<210>  585
<211>  165
<212>  PRT
<213>  Homo Sapiens

<400>  585

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Ser Arg Arg Thr Leu Met 
1               5                   10                  15      


Leu Leu Ala Gln Met Arg Arg Ile Ser Leu Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Phe Pro Gln Glu Glu Phe Gly Asn Gln Phe Gln 
        35                  40                  45              


Lys Ala Glu Thr Ile Pro Val Leu His Glu Met Ile Gln Gln Ile Phe 
    50                  55                  60                  


Asn Leu Phe Ser Thr Lys Asp Ser Ser Ala Ala Trp Asp Glu Thr Leu 
65                  70                  75                  80  


Leu Asp Lys Phe Tyr Thr Glu Leu Tyr Gln Gln Leu Asn Asp Leu Glu 
                85                  90                  95      


Ala Cys Val Ile Gln Gly Val Gly Val Thr Glu Thr Pro Leu Met Lys 
            100                 105                 110         


Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr Leu 
        115                 120                 125             


Tyr Leu Lys Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val Arg 
    130                 135                 140                 


Ala Glu Ile Met Arg Ser Phe Ser Leu Ser Thr Asn Leu Gln Glu Ser 
145                 150                 155                 160 


Leu Arg Ser Lys Glu 
                165 


<210>  586
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  586

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Gly Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Phe Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Lys Asp Ser Ser Ala Thr Trp Glu Gln Ser 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Ser Thr Glu Leu Asn Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Val Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Val Asp Ser Ile Leu Ala Val Lys Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Phe Ser Leu Ser Lys Ile Phe Gln Glu 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Glu 
                165     


<210>  587
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  587

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Gly Arg Ile Ser His Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Phe Pro Glu Glu Glu Phe Asp Gly His Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Glu Asp Ser Ser Ala Ala Trp Glu Gln Ser 
65                  70                  75                  80  


Leu Leu Glu Lys Phe Ser Thr Glu Leu Tyr Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Val Ile Gln Glu Val Gly Val Glu Glu Thr Pro Leu Met 
            100                 105                 110         


Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Leu Ser Phe Ser Thr Asn Leu Gln Lys 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Asp 
                165     


<210>  588
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  588

Cys Asp Leu Pro Gln Thr His Ser Leu Ser Asn Arg Arg Thr Leu Met 
1               5                   10                  15      


Ile Met Ala Gln Met Gly Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Gly Phe Pro Gln Glu Glu Phe Asp Gly Asn Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Lys Asp Ser Ser Ala Thr Trp Asp Glu Thr 
65                  70                  75                  80  


Leu Leu Asp Lys Phe Tyr Thr Glu Leu Tyr Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ala Cys Met Met Gln Glu Val Gly Val Glu Asp Thr Pro Leu Met 
            100                 105                 110         


Asn Val Asp Ser Ile Leu Thr Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Phe Ser Leu Ser Ala Asn Leu Gln Glu 
145                 150                 155                 160 


Arg Leu Arg Arg Lys Glu 
                165     


<210>  589
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  589

Ser Leu Asp Cys Asp Leu Pro Gln Thr His Ser Leu Gly His Arg Arg 
1               5                   10                  15      


Thr Met Met Leu Leu Ala Gln Met Arg Arg Ile Ser Leu Phe Ser Cys 
            20                  25                  30          


Leu Lys Asp Arg His Asp Phe Arg Phe Pro Gln Glu Glu Phe Asp Gly 
        35                  40                  45              


Asn Gln Phe Gln Lys Ala Glu Ala Ile Ser Val Leu His Glu Val Ile 
    50                  55                  60                  


Gln Gln Thr Phe Asn Leu Phe Ser Thr Lys Asp Ser Ser Val Ala Trp 
65                  70                  75                  80  


Asp Glu Arg Leu Leu Asp Lys Leu Tyr Thr Glu Leu Tyr Gln Gln Leu 
                85                  90                  95      


Asn Asp Leu Glu Ala Cys Val Met Gln Glu Val Trp Val Gly Gly Thr 
            100                 105                 110         


Pro Leu Met Asn Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln 
        115                 120                 125             


Arg Ile Thr Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Pro Cys Ala Trp 
    130                 135                 140                 


Glu Val Val Arg Ala Glu Ile Met Arg Ser Phe Ser Ser Ser Arg Asn 
145                 150                 155                 160 


Leu Gln Glu Arg Leu Arg Arg Lys Glu 
                165                 


<210>  590
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  590

Cys Asp Leu Pro Gln Thr His Ser Leu Gly Asn Arg Arg Ala Leu Ile 
1               5                   10                  15      


Leu Leu Ala Gln Met Arg Arg Ile Ser Pro Phe Ser Cys Leu Lys Asp 
            20                  25                  30          


Arg His Asp Phe Glu Phe Pro Gln Glu Glu Phe Asp Asp Lys Gln Phe 
        35                  40                  45              


Gln Lys Ala Gln Ala Ile Ser Val Leu His Glu Met Ile Gln Gln Thr 
    50                  55                  60                  


Phe Asn Leu Phe Ser Thr Lys Asp Ser Ser Ala Ala Leu Asp Glu Thr 
65                  70                  75                  80  


Leu Leu Asp Glu Phe Tyr Ile Glu Leu Asp Gln Gln Leu Asn Asp Leu 
                85                  90                  95      


Glu Ser Cys Val Met Gln Glu Val Gly Val Ile Glu Ser Pro Leu Met 
            100                 105                 110         


Tyr Glu Asp Ser Ile Leu Ala Val Arg Lys Tyr Phe Gln Arg Ile Thr 
        115                 120                 125             


Leu Tyr Leu Thr Glu Lys Lys Tyr Ser Ser Cys Ala Trp Glu Val Val 
    130                 135                 140                 


Arg Ala Glu Ile Met Arg Ser Phe Ser Leu Ser Ile Asn Leu Gln Lys 
145                 150                 155                 160 


Arg Leu Lys Ser Lys Glu 
                165     


<210>  591
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  591

Lys Asn Leu Lys Ser Pro Gln Lys Val Glu Val Asp Ile Ile Asp Asp 
1               5                   10                  15      


Asn Phe Ile Leu Arg Trp Asn Arg Ser Asp Glu Ser Val Gly Asn Val 
            20                  25                  30          


Thr Phe Ser Phe Asp Tyr Gln Lys Thr Gly Met Asp Asn Trp Ile Lys 
        35                  40                  45              


Leu Ser Gly Cys Gln Asn Ile Thr Ser Thr Lys Cys Asn Phe Ser Ser 
    50                  55                  60                  


Leu Lys Leu Asn Val Tyr Glu Glu Ile Lys Leu Arg Ile Arg Ala Glu 
65                  70                  75                  80  


Lys Glu Asn Thr Ser Ser Trp Tyr Glu Val Asp Ser Phe Thr Pro Phe 
                85                  90                  95      


Arg Lys Ala Gln Ile Gly Pro Pro Glu Val His Leu Glu Ala Glu Asp 
            100                 105                 110         


Lys Ala Ile Val Ile His Ile Ser Pro Gly Thr Lys Asp Ser Val Met 
        115                 120                 125             


Trp Ala Leu Asp Gly Leu Ser Phe Thr Tyr Ser Leu Val Ile Trp Lys 
    130                 135                 140                 


Asn Ser Ser Gly Val Glu Glu Arg Ile Glu Asn Ile Tyr Ser Arg His 
145                 150                 155                 160 


Lys Ile Tyr Lys Leu Ser Pro Glu Thr Thr Tyr Cys Leu Lys Val Lys 
                165                 170                 175     


Ala Ala Leu Leu Thr Ser Trp Lys Ile Gly Val Tyr Ser Pro Val His 
            180                 185                 190         


Cys Ile Lys Thr Thr Val Glu Asn Glu Leu Pro Pro Pro Glu Asn Ile 
        195                 200                 205             


Glu Val Ser Val Gln Asn Gln Asn Tyr Val Leu Lys Trp Asp Tyr Thr 
    210                 215                 220                 


Tyr Ala Asn Met Thr Phe Gln Val Gln Trp Leu His Ala Phe Leu Lys 
225                 230                 235                 240 


Arg Asn Pro Gly Asn His Leu Tyr Lys Trp Lys Gln Ile Pro Asp Cys 
                245                 250                 255     


Glu Asn Val Lys Thr Thr Gln Cys Val Phe Pro Gln Asn Val Phe Gln 
            260                 265                 270         


Lys Gly Ile Tyr Leu Leu Arg Val Gln Ala Ser Asp Gly Asn Asn Thr 
        275                 280                 285             


Ser Phe Trp Ser Glu Glu Ile Lys Phe Asp Thr Glu Ile Gln Ala Phe 
    290                 295                 300                 


Leu Leu Pro Pro Val Phe Asn Ile Arg Ser Leu Ser Asp Ser Phe His 
305                 310                 315                 320 


Ile Tyr Ile Gly Ala Pro Lys Gln Ser Gly Asn Thr Pro Val Ile Gln 
                325                 330                 335     


Asp Tyr Pro Leu Ile Tyr Glu Ile Ile Phe Trp Glu Asn Thr Ser Asn 
            340                 345                 350         


Ala Glu Arg Lys Ile Ile Glu Lys Lys Thr Asp Val Thr Val Pro Asn 
        355                 360                 365             


Leu Lys Pro Leu Thr Val Tyr Cys Val Lys Ala Arg Ala His Thr Met 
    370                 375                 380                 


Asp Glu Lys Leu Asn Lys Ser Ser Val Phe Ser Asp Ala Val Cys Glu 
385                 390                 395                 400 


Lys Thr Lys Pro Gly Asn Thr Ser Lys 
                405                 


<210>  592
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  592

Ile Ser Tyr Asp Ser Pro Asp Tyr Thr Asp Glu Ser Cys Thr Phe Lys 
1               5                   10                  15      


Ile Ser Leu Arg Asn Phe Arg Ser Ile Leu Ser Trp Glu Leu Lys Asn 
            20                  25                  30          


His Ser Ile Val Pro Thr His Tyr Thr Leu Leu Tyr Thr Ile Met Ser 
        35                  40                  45              


Lys Pro Glu Asp Leu Lys Val Val Lys Asn Cys Ala Asn Thr Thr Arg 
    50                  55                  60                  


Ser Phe Cys Asp Leu Thr Asp Glu Trp Arg Ser Thr His Glu Ala Tyr 
65                  70                  75                  80  


Val Thr Val Leu Glu Gly Phe Ser Gly Asn Thr Thr Leu Phe Ser Cys 
                85                  90                  95      


Ser His Asn Phe Trp Leu Ala Ile Asp Met Ser Phe Glu Pro Pro Glu 
            100                 105                 110         


Phe Glu Ile Val Gly Phe Thr Asn His Ile Asn Val Met Val Lys Phe 
        115                 120                 125             


Pro Ser Ile Val Glu Glu Glu Leu Gln Phe Asp Leu Ser Leu Val Ile 
    130                 135                 140                 


Glu Glu Gln Ser Glu Gly Ile Val Lys Lys His Lys Pro Glu Ile Lys 
145                 150                 155                 160 


Gly Asn Met Ser Gly Asn Phe Thr Tyr Ile Ile Asp Lys Leu Ile Pro 
                165                 170                 175     


Asn Thr Asn Tyr Cys Val Ser Val Tyr Leu Glu His Ser Asp Glu Gln 
            180                 185                 190         


Ala Val Ile Lys Ser Pro Leu Lys Cys Thr Leu Leu Pro Pro Gly Gln 
        195                 200                 205             


Glu Ser Glu Ser Ala Glu Ser Ala Lys 
    210                 215         


<210>  593
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  593

Met Ser Tyr Asn Leu Leu Gly Phe Leu Gln Arg Ser Ser Asn Phe Gln 
1               5                   10                  15      


Cys Gln Lys Leu Leu Trp Gln Leu Asn Gly Arg Leu Glu Tyr Cys Leu 
            20                  25                  30          


Lys Asp Arg Met Asn Phe Asp Ile Pro Glu Glu Ile Lys Gln Leu Gln 
        35                  40                  45              


Gln Phe Gln Lys Glu Asp Ala Ala Leu Thr Ile Tyr Glu Met Leu Gln 
    50                  55                  60                  


Asn Ile Phe Ala Ile Phe Arg Gln Asp Ser Ser Ser Thr Gly Trp Asn 
65                  70                  75                  80  


Glu Thr Ile Val Glu Asn Leu Leu Ala Asn Val Tyr His Gln Ile Asn 
                85                  90                  95      


His Leu Lys Thr Val Leu Glu Glu Lys Leu Glu Lys Glu Asp Phe Thr 
            100                 105                 110         


Arg Gly Lys Leu Met Ser Ser Leu His Leu Lys Arg Tyr Tyr Gly Arg 
        115                 120                 125             


Ile Leu His Tyr Leu Lys Ala Lys Glu Tyr Ser His Cys Ala Trp Thr 
    130                 135                 140                 


Ile Val Arg Val Glu Ile Leu Arg Asn Phe Tyr Phe Ile Asn Arg Leu 
145                 150                 155                 160 


Thr Gly Tyr Leu Arg Asn 
                165     


<210>  594
<211>  187
<212>  PRT
<213>  Homo Sapiens

<400>  594

Leu Asp Leu Lys Leu Ile Ile Phe Gln Gln Arg Gln Val Asn Gln Glu 
1               5                   10                  15      


Ser Leu Lys Leu Leu Asn Lys Leu Gln Thr Leu Ser Ile Gln Gln Cys 
            20                  25                  30          


Leu Pro His Arg Lys Asn Phe Leu Leu Pro Gln Lys Ser Leu Ser Pro 
        35                  40                  45              


Gln Gln Tyr Gln Lys Gly His Thr Leu Ala Ile Leu His Glu Met Leu 
    50                  55                  60                  


Gln Gln Ile Phe Ser Leu Phe Arg Ala Asn Ile Ser Leu Asp Gly Trp 
65                  70                  75                  80  


Glu Glu Asn His Thr Glu Lys Phe Leu Ile Gln Leu His Gln Gln Leu 
                85                  90                  95      


Glu Tyr Leu Glu Ala Leu Met Gly Leu Glu Ala Glu Lys Leu Ser Gly 
            100                 105                 110         


Thr Leu Gly Ser Asp Asn Leu Arg Leu Gln Val Lys Met Tyr Phe Arg 
        115                 120                 125             


Arg Ile His Asp Tyr Leu Glu Asn Gln Asp Tyr Ser Thr Cys Ala Trp 
    130                 135                 140                 


Ala Ile Val Gln Val Glu Ile Ser Arg Cys Leu Phe Phe Val Phe Ser 
145                 150                 155                 160 


Leu Thr Glu Lys Leu Ser Lys Gln Gly Arg Pro Leu Asn Asp Met Lys 
                165                 170                 175     


Gln Glu Leu Thr Thr Glu Phe Arg Ser Pro Arg 
            180                 185         


<210>  595
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  595

Gln Asp Pro Tyr Val Lys Glu Ala Glu Asn Leu Lys Lys Tyr Phe Asn 
1               5                   10                  15      


Ala Gly His Ser Asp Val Ala Asp Asn Gly Thr Leu Phe Leu Gly Ile 
            20                  25                  30          


Leu Lys Asn Trp Lys Glu Glu Ser Asp Arg Lys Ile Met Gln Ser Gln 
        35                  40                  45              


Ile Val Ser Phe Tyr Phe Lys Leu Phe Lys Asn Phe Lys Asp Asp Gln 
    50                  55                  60                  


Ser Ile Gln Lys Ser Val Glu Thr Ile Lys Glu Asp Met Asn Val Lys 
65                  70                  75                  80  


Phe Phe Asn Ser Asn Lys Lys Lys Arg Asp Asp Phe Glu Lys Leu Thr 
                85                  90                  95      


Asn Tyr Ser Val Thr Asp Leu Asn Val Gln Arg Lys Ala Ile His Glu 
            100                 105                 110         


Leu Ile Gln Val Met Ala Glu Leu Ser Pro Ala Ala Lys Thr Gly Lys 
        115                 120                 125             


Arg Lys Arg Ser Gln Met Leu Phe Arg Gly 
    130                 135             


<210>  596
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  596

Glu Met Gly Thr Ala Asp Leu Gly Pro Ser Ser Val Pro Thr Pro Thr 
1               5                   10                  15      


Asn Val Thr Ile Glu Ser Tyr Asn Met Asn Pro Ile Val Tyr Trp Glu 
            20                  25                  30          


Tyr Gln Ile Met Pro Gln Val Pro Val Phe Thr Val Glu Val Lys Asn 
        35                  40                  45              


Tyr Gly Val Lys Asn Ser Glu Trp Ile Asp Ala Cys Ile Asn Ile Ser 
    50                  55                  60                  


His His Tyr Cys Asn Ile Ser Asp His Val Gly Asp Pro Ser Asn Ser 
65                  70                  75                  80  


Leu Trp Val Arg Val Lys Ala Arg Val Gly Gln Lys Glu Ser Ala Tyr 
                85                  90                  95      


Ala Lys Ser Glu Glu Phe Ala Val Cys Arg Asp Gly Lys Ile Gly Pro 
            100                 105                 110         


Pro Lys Leu Asp Ile Arg Lys Glu Glu Lys Gln Ile Met Ile Asp Ile 
        115                 120                 125             


Phe His Pro Ser Val Phe Val Asn Gly Asp Glu Gln Glu Val Asp Tyr 
    130                 135                 140                 


Asp Pro Glu Thr Thr Cys Tyr Ile Arg Val Tyr Asn Val Tyr Val Arg 
145                 150                 155                 160 


Met Asn Gly Ser Glu Ile Gln Tyr Lys Ile Leu Thr Gln Lys Glu Asp 
                165                 170                 175     


Asp Cys Asp Glu Ile Gln Cys Gln Leu Ala Ile Pro Val Ser Ser Leu 
            180                 185                 190         


Asn Ser Gln Tyr Cys Val Ser Ala Glu Gly Val Leu His Val Trp Gly 
        195                 200                 205             


Val Thr Thr Glu Lys Ser Lys Glu Val Cys Ile Thr Ile Phe Asn Ser 
    210                 215                 220                 


Ser Ile Lys Gly 
225             


<210>  597
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  597

Ser Gln Leu Pro Ala Pro Gln His Pro Lys Ile Arg Leu Tyr Asn Ala 
1               5                   10                  15      


Glu Gln Val Leu Ser Trp Glu Pro Val Ala Leu Ser Asn Ser Thr Arg 
            20                  25                  30          


Pro Val Val Tyr Gln Val Gln Phe Lys Tyr Thr Asp Ser Lys Trp Phe 
        35                  40                  45              


Thr Ala Asp Ile Met Ser Ile Gly Val Asn Cys Thr Gln Ile Thr Ala 
    50                  55                  60                  


Thr Glu Cys Asp Phe Thr Ala Ala Ser Pro Ser Ala Gly Phe Pro Met 
65                  70                  75                  80  


Asp Phe Asn Val Thr Leu Arg Leu Arg Ala Glu Leu Gly Ala Leu His 
                85                  90                  95      


Ser Ala Trp Val Thr Met Pro Trp Phe Gln His Tyr Arg Asn Val Thr 
            100                 105                 110         


Val Gly Pro Pro Glu Asn Ile Glu Val Thr Pro Gly Glu Gly Ser Leu 
        115                 120                 125             


Ile Ile Arg Phe Ser Ser Pro Phe Asp Ile Ala Asp Thr Ser Thr Ala 
    130                 135                 140                 


Phe Phe Cys Tyr Tyr Val His Tyr Trp Glu Lys Gly Gly Ile Gln Gln 
145                 150                 155                 160 


Val Lys Gly Pro Phe Arg Ser Asn Ser Ile Ser Leu Asp Asn Leu Lys 
                165                 170                 175     


Pro Ser Arg Val Tyr Cys Leu Gln Val Gln Ala Gln Leu Leu Trp Asn 
            180                 185                 190         


Lys Ser Asn Ile Phe Arg Val Gly His Leu Ser Asn Ile Ser Cys Tyr 
        195                 200                 205             


Glu Thr Met Ala Asp Ala Ser Thr Glu Leu Gln Gln 
    210                 215                 220 


<210>  598
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  598

Leu Asp Cys Asn Leu Leu Asn Val His Leu Arg Arg Val Thr Trp Gln 
1               5                   10                  15      


Asn Leu Arg His Leu Ser Ser Met Ser Asn Ser Phe Pro Val Glu Cys 
            20                  25                  30          


Leu Arg Glu Asn Ile Ala Phe Glu Leu Pro Gln Glu Phe Leu Gln Tyr 
        35                  40                  45              


Thr Gln Pro Met Lys Arg Asp Ile Lys Lys Ala Phe Tyr Glu Met Ser 
    50                  55                  60                  


Leu Gln Ala Phe Asn Ile Phe Ser Gln His Thr Phe Lys Tyr Trp Lys 
65                  70                  75                  80  


Glu Arg His Leu Lys Gln Ile Gln Ile Gly Leu Asp Gln Gln Ala Glu 
                85                  90                  95      


Tyr Leu Asn Gln Cys Leu Glu Glu Asp Lys Asn Glu Asn Glu Asp Met 
            100                 105                 110         


Lys Glu Met Lys Glu Asn Glu Met Lys Pro Ser Glu Ala Arg Val Pro 
        115                 120                 125             


Gln Leu Ser Ser Leu Glu Leu Arg Arg Tyr Phe His Arg Ile Asp Asn 
    130                 135                 140                 


Phe Leu Lys Glu Lys Lys Tyr Ser Asp Cys Ala Trp Glu Ile Val Arg 
145                 150                 155                 160 


Val Glu Ile Arg Arg Cys Leu Tyr Tyr Phe Tyr Lys Phe Thr Ala Leu 
                165                 170                 175     


Phe Arg Arg Lys 
            180 


<210>  599
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  599

Val Pro Val Ala Arg Leu His Gly Ala Leu Pro Asp Ala Arg Gly Cys 
1               5                   10                  15      


His Ile Ala Gln Phe Lys Ser Leu Ser Pro Gln Glu Leu Gln Ala Phe 
            20                  25                  30          


Lys Arg Ala Lys Asp Ala Leu Glu Glu Ser Leu Leu Leu Lys Asp Cys 
        35                  40                  45              


Arg Cys His Ser Arg Leu Phe Pro Arg Thr Trp Asp Leu Arg Gln Leu 
    50                  55                  60                  


Gln Val Arg Glu Arg Pro Met Ala Leu Glu Ala Glu Leu Ala Leu Thr 
65                  70                  75                  80  


Leu Lys Val Leu Glu Ala Thr Ala Asp Thr Asp Pro Ala Leu Val Asp 
                85                  90                  95      


Val Leu Asp Gln Pro Leu His Thr Leu His His Ile Leu Ser Gln Phe 
            100                 105                 110         


Arg Ala Cys Ile Gln Pro Gln Pro Thr Ala Gly Pro Arg Thr Arg Gly 
        115                 120                 125             


Arg Leu His His Trp Leu Tyr Arg Leu Gln Glu Ala Pro Lys Lys Glu 
    130                 135                 140                 


Ser Pro Gly Cys Leu Glu Ala Ser Val Thr Phe Asn Leu Phe Arg Leu 
145                 150                 155                 160 


Leu Thr Arg Asp Leu Asn Cys Val Ala Ser Gly Asp Leu Cys Val 
                165                 170                 175 


<210>  600
<211>  174
<212>  PRT
<213>  Homo Sapiens

<400>  600

Leu Gly Cys Asp Leu Pro Gln Asn His Gly Leu Leu Ser Arg Asn Thr 
1               5                   10                  15      


Leu Val Leu Leu His Gln Met Arg Arg Ile Ser Pro Phe Leu Cys Leu 
            20                  25                  30          


Lys Asp Arg Arg Asp Phe Arg Phe Pro Gln Glu Met Val Lys Gly Ser 
        35                  40                  45              


Gln Leu Gln Lys Ala His Val Met Ser Val Leu His Glu Met Leu Gln 
    50                  55                  60                  


Gln Ile Phe Ser Leu Phe His Thr Glu Arg Ser Ser Ala Ala Trp Asn 
65                  70                  75                  80  


Met Thr Leu Leu Asp Gln Leu His Thr Gly Leu His Gln Gln Leu Gln 
                85                  90                  95      


His Leu Glu Thr Cys Leu Leu Gln Val Val Gly Glu Gly Glu Ser Ala 
            100                 105                 110         


Gly Ala Ile Ser Ser Pro Ala Leu Thr Leu Arg Arg Tyr Phe Gln Gly 
        115                 120                 125             


Ile Arg Val Tyr Leu Lys Glu Lys Lys Tyr Ser Asp Cys Ala Trp Glu 
    130                 135                 140                 


Val Val Arg Met Glu Ile Met Lys Ser Leu Phe Leu Ser Thr Asn Met 
145                 150                 155                 160 


Gln Glu Arg Leu Arg Ser Lys Asp Arg Asp Leu Gly Ser Ser 
                165                 170                 


<210>  601
<211>  605
<212>  PRT
<213>  Homo Sapiens

<400>  601

Leu Gly His Ser Ala Glu Leu Ala Phe Ala Val Glu Pro Ser Asp Asp 
1               5                   10                  15      


Val Ala Val Pro Gly Gln Pro Ile Val Leu Asp Cys Arg Val Glu Gly 
            20                  25                  30          


Thr Pro Pro Val Arg Ile Thr Trp Arg Lys Asn Gly Val Glu Leu Pro 
        35                  40                  45              


Glu Ser Thr His Ser Thr Leu Leu Ala Asn Gly Ser Leu Met Ile Arg 
    50                  55                  60                  


His Phe Arg Leu Glu Pro Gly Gly Ser Pro Ser Asp Glu Gly Asp Tyr 
65                  70                  75                  80  


Glu Cys Val Ala Gln Asn Arg Phe Gly Leu Val Val Ser Arg Lys Ala 
                85                  90                  95      


Arg Ile Gln Ala Ala Thr Met Ser Asp Phe His Val His Pro Gln Ala 
            100                 105                 110         


Thr Val Gly Glu Glu Gly Gly Val Ala Arg Phe Gln Cys Gln Ile His 
        115                 120                 125             


Gly Leu Pro Lys Pro Leu Ile Thr Trp Glu Lys Asn Arg Val Pro Ile 
    130                 135                 140                 


Asp Thr Asp Asn Glu Arg Tyr Thr Leu Leu Pro Lys Gly Val Leu Gln 
145                 150                 155                 160 


Ile Thr Gly Leu Arg Ala Glu Asp Gly Gly Ile Phe His Cys Val Ala 
                165                 170                 175     


Ser Asn Ile Ala Ser Ile Arg Ile Ser His Gly Ala Arg Leu Thr Val 
            180                 185                 190         


Ser Gly Ser Gly Ser Gly Ala Tyr Lys Glu Pro Ala Ile Leu Val Gly 
        195                 200                 205             


Pro Glu Asn Leu Thr Leu Thr Val His Gln Thr Ala Val Leu Glu Cys 
    210                 215                 220                 


Val Ala Thr Gly Asn Pro Arg Pro Ile Val Ser Trp Ser Arg Leu Asp 
225                 230                 235                 240 


Gly Arg Pro Ile Gly Val Glu Gly Ile Gln Val Leu Gly Thr Gly Asn 
                245                 250                 255     


Leu Ile Ile Ser Asp Val Thr Val Gln His Ser Gly Val Tyr Val Cys 
            260                 265                 270         


Ala Ala Asn Arg Pro Gly Thr Arg Val Arg Arg Thr Ala Gln Gly Arg 
        275                 280                 285             


Leu Val Val Gln Ala Pro Ala Glu Phe Val Gln His Pro Gln Ser Ile 
    290                 295                 300                 


Ser Arg Pro Ala Gly Thr Thr Ala Met Phe Thr Cys Gln Ala Gln Gly 
305                 310                 315                 320 


Glu Pro Pro Pro His Val Thr Trp Leu Lys Asn Gly Gln Val Leu Gly 
                325                 330                 335     


Pro Gly Gly His Val Arg Leu Lys Asn Asn Asn Ser Thr Leu Thr Ile 
            340                 345                 350         


Ser Gly Ile Gly Pro Glu Asp Glu Ala Ile Tyr Gln Cys Val Ala Glu 
        355                 360                 365             


Asn Ser Ala Gly Ser Ser Gln Ala Ser Ala Arg Leu Thr Val Leu Trp 
    370                 375                 380                 


Ala Glu Gly Leu Pro Gly Pro Pro Arg Asn Val Arg Ala Val Ser Val 
385                 390                 395                 400 


Ser Ser Thr Glu Val Arg Val Ser Trp Ser Glu Pro Leu Ala Asn Thr 
                405                 410                 415     


Lys Glu Ile Ile Gly Tyr Val Leu His Ile Arg Lys Ala Ala Asp Pro 
            420                 425                 430         


Pro Glu Leu Glu Tyr Gln Glu Ala Val Ser Lys Ser Thr Phe Gln His 
        435                 440                 445             


Leu Val Ser Asp Leu Glu Pro Ser Thr Ala Tyr Ser Phe Tyr Ile Lys 
    450                 455                 460                 


Ala Tyr Thr Pro Arg Gly Ala Ser Ser Ala Ser Val Pro Thr Leu Ala 
465                 470                 475                 480 


Ser Thr Leu Gly Glu Ala Pro Ala Pro Pro Pro Leu Ser Val Arg Val 
                485                 490                 495     


Leu Gly Ser Ser Ser Leu Gln Leu Leu Trp Glu Pro Trp Pro Arg Leu 
            500                 505                 510         


Ala Gln His Glu Gly Gly Phe Lys Leu Phe Tyr Arg Pro Ala Ser Lys 
        515                 520                 525             


Thr Ser Phe Thr Gly Pro Ile Leu Leu Pro Gly Thr Val Ser Ser Tyr 
    530                 535                 540                 


Asn Leu Ser Gln Leu Asp Pro Thr Ala Val Tyr Glu Val Lys Leu Leu 
545                 550                 555                 560 


Ala Tyr Asn Gln His Gly Asp Gly Asn Ala Thr Val Arg Phe Val Ser 
                565                 570                 575     


Leu Arg Gly Ala Ser Glu Arg Thr Ala Leu Ser Pro Pro Cys Asp Cys 
            580                 585                 590         


Arg Lys Glu Glu Ala Ala Asn Gln Thr Ser Thr Thr Gly 
        595                 600                 605 


<210>  602
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  602

Ala Tyr Arg Pro Ser Glu Thr Leu Cys Gly Gly Glu Leu Val Asp Thr 
1               5                   10                  15      


Leu Gln Phe Val Cys Gly Asp Arg Gly Phe Tyr Phe Ser Arg Pro Ala 
            20                  25                  30          


Ser Arg Val Ser Arg Arg Ser Arg Gly Ile Val Glu Glu Cys Cys Phe 
        35                  40                  45              


Arg Ser Cys Asp Leu Ala Leu Leu Glu Thr Tyr Cys Ala Thr Pro Ala 
    50                  55                  60                  


Lys Ser Glu 
65          


<210>  603
<211>  920
<212>  PRT
<213>  Homo Sapiens

<400>  603

Ser Arg Tyr Ser Asp Asn Trp Glu Ala Ile Thr Gly Thr Gly Asp Pro 
1               5                   10                  15      


Glu His Tyr Leu Ile Asn Val Cys Lys Ser Leu Ala Pro Gln Ala Gly 
            20                  25                  30          


Thr Glu Pro Cys Pro Pro Glu Ala Ala Ala Cys Leu Leu Gly Gly Ser 
        35                  40                  45              


Lys Pro Val Asn Leu Gly Arg Val Arg Asp Gly Pro Gln Trp Arg Asp 
    50                  55                  60                  


Gly Ile Ile Val Leu Lys Tyr Val Asp Gly Asp Leu Cys Pro Asp Gly 
65                  70                  75                  80  


Ile Arg Lys Lys Ser Thr Thr Ile Arg Phe Thr Cys Ser Glu Ser Gln 
                85                  90                  95      


Val Asn Ser Arg Pro Met Phe Ile Ser Ala Val Glu Asp Cys Glu Tyr 
            100                 105                 110         


Thr Phe Ala Trp Pro Thr Ala Thr Ala Cys Pro Met Lys Ser Asn Glu 
        115                 120                 125             


His Asp Asp Cys Gln Val Thr Asn Pro Ser Thr Gly His Leu Phe Asp 
    130                 135                 140                 


Leu Ser Ser Leu Ser Gly Arg Ala Gly Phe Thr Ala Ala Tyr Ser Glu 
145                 150                 155                 160 


Lys Gly Leu Val Tyr Met Ser Ile Cys Gly Glu Asn Glu Asn Cys Pro 
                165                 170                 175     


Pro Gly Val Gly Ala Cys Phe Gly Gln Thr Arg Ile Ser Val Gly Lys 
            180                 185                 190         


Ala Asn Lys Arg Leu Arg Tyr Val Asp Gln Val Leu Gln Leu Val Tyr 
        195                 200                 205             


Lys Asp Gly Ser Pro Cys Pro Ser Lys Ser Gly Leu Ser Tyr Lys Ser 
    210                 215                 220                 


Val Ile Ser Phe Val Cys Arg Pro Glu Ala Gly Pro Thr Asn Arg Pro 
225                 230                 235                 240 


Met Leu Ile Ser Leu Asp Lys Gln Thr Cys Thr Leu Phe Phe Ser Trp 
                245                 250                 255     


His Thr Pro Leu Ala Cys Glu Gln Ala Thr Glu Cys Ser Val Arg Asn 
            260                 265                 270         


Gly Ser Ser Ile Val Asp Leu Ser Pro Leu Ile His Arg Thr Gly Gly 
        275                 280                 285             


Tyr Glu Ala Tyr Asp Glu Ser Glu Asp Asp Ala Ser Asp Thr Asn Pro 
    290                 295                 300                 


Asp Phe Tyr Ile Asn Ile Cys Gln Pro Leu Asn Pro Met His Gly Val 
305                 310                 315                 320 


Pro Cys Pro Ala Gly Ala Ala Val Cys Lys Val Pro Ile Asp Gly Pro 
                325                 330                 335     


Pro Ile Asp Ile Gly Arg Val Ala Gly Pro Pro Ile Leu Asn Pro Ile 
            340                 345                 350         


Ala Asn Glu Ile Tyr Leu Asn Phe Glu Ser Ser Thr Pro Cys Leu Ala 
        355                 360                 365             


Asp Lys His Phe Asn Tyr Thr Ser Leu Ile Ala Phe His Cys Lys Arg 
    370                 375                 380                 


Gly Val Ser Met Gly Thr Pro Lys Leu Leu Arg Thr Ser Glu Cys Asp 
385                 390                 395                 400 


Phe Val Phe Glu Trp Glu Thr Pro Val Val Cys Pro Asp Glu Val Arg 
                405                 410                 415     


Met Asp Gly Cys Thr Leu Thr Asp Glu Gln Leu Leu Tyr Ser Phe Asn 
            420                 425                 430         


Leu Ser Ser Leu Ser Thr Ser Thr Phe Lys Val Thr Arg Asp Ser Arg 
        435                 440                 445             


Thr Tyr Ser Val Gly Val Cys Thr Phe Ala Val Gly Pro Glu Gln Gly 
    450                 455                 460                 


Gly Cys Lys Asp Gly Gly Val Cys Leu Leu Ser Gly Thr Lys Gly Ala 
465                 470                 475                 480 


Ser Phe Gly Arg Leu Gln Ser Met Lys Leu Asp Tyr Arg His Gln Asp 
                485                 490                 495     


Glu Ala Val Val Leu Ser Tyr Val Asn Gly Asp Arg Cys Pro Pro Glu 
            500                 505                 510         


Thr Asp Asp Gly Val Pro Cys Val Phe Pro Phe Ile Phe Asn Gly Lys 
        515                 520                 525             


Ser Tyr Glu Glu Cys Ile Ile Glu Ser Arg Ala Lys Leu Trp Cys Ser 
    530                 535                 540                 


Thr Thr Ala Asp Tyr Asp Arg Asp His Glu Trp Gly Phe Cys Arg His 
545                 550                 555                 560 


Ser Asn Ser Tyr Arg Thr Ser Ser Ile Ile Phe Lys Cys Asp Glu Asp 
                565                 570                 575     


Glu Asp Ile Gly Arg Pro Gln Val Phe Ser Glu Val Arg Gly Cys Asp 
            580                 585                 590         


Val Thr Phe Glu Trp Lys Thr Lys Val Val Cys Pro Pro Lys Lys Leu 
        595                 600                 605             


Glu Cys Lys Phe Val Gln Lys His Lys Thr Tyr Asp Leu Arg Leu Leu 
    610                 615                 620                 


Ser Ser Leu Thr Gly Ser Trp Ser Leu Val His Asn Gly Val Ser Tyr 
625                 630                 635                 640 


Tyr Ile Asn Leu Cys Gln Lys Ile Tyr Lys Gly Pro Leu Gly Cys Ser 
                645                 650                 655     


Glu Arg Ala Ser Ile Cys Arg Arg Thr Thr Thr Gly Asp Val Gln Val 
            660                 665                 670         


Leu Gly Leu Val His Thr Gln Lys Leu Gly Val Ile Gly Asp Lys Val 
        675                 680                 685             


Val Val Thr Tyr Ser Lys Gly Tyr Pro Cys Gly Gly Asn Lys Thr Ala 
    690                 695                 700                 


Ser Ser Val Ile Glu Leu Thr Cys Thr Lys Thr Val Gly Arg Pro Ala 
705                 710                 715                 720 


Phe Lys Arg Phe Asp Ile Asp Ser Cys Thr Tyr Tyr Phe Ser Trp Asp 
                725                 730                 735     


Ser Arg Ala Ala Cys Ala Val Lys Pro Gln Glu Val Gln Met Val Asn 
            740                 745                 750         


Gly Thr Ile Thr Asn Pro Ile Asn Gly Lys Ser Phe Ser Leu Gly Asp 
        755                 760                 765             


Ile Tyr Phe Lys Leu Phe Arg Ala Ser Gly Asp Met Arg Thr Asn Gly 
    770                 775                 780                 


Asp Asn Tyr Leu Tyr Glu Ile Gln Leu Ser Ser Ile Thr Ser Ser Arg 
785                 790                 795                 800 


Asn Pro Ala Cys Ser Gly Ala Asn Ile Cys Gln Val Lys Pro Asn Asp 
                805                 810                 815     


Gln His Phe Ser Arg Lys Val Gly Thr Ser Asp Lys Thr Lys Tyr Tyr 
            820                 825                 830         


Leu Gln Asp Gly Asp Leu Asp Val Val Phe Ala Ser Ser Ser Lys Cys 
        835                 840                 845             


Gly Lys Asp Lys Thr Lys Ser Val Ser Ser Thr Ile Phe Phe His Cys 
    850                 855                 860                 


Asp Pro Leu Val Glu Asp Gly Ile Pro Glu Phe Ser His Glu Thr Ala 
865                 870                 875                 880 


Asp Cys Gln Tyr Leu Phe Ser Trp Tyr Thr Ser Ala Val Cys Pro Leu 
                885                 890                 895     


Gly Val Gly Phe Asp Ser Glu Asn Pro Gly Asp Asp Gly Gln Met His 
            900                 905                 910         


Lys Gly Leu Ser Glu Arg Ser Gln 
        915                 920 


<210>  604
<211>  578
<212>  PRT
<213>  Homo Sapiens

<400>  604

Ala Asp Pro Gly Thr Pro Gly Glu Ala Glu Gly Pro Ala Cys Pro Ala 
1               5                   10                  15      


Ala Cys Val Cys Ser Tyr Asp Asp Asp Ala Asp Glu Leu Ser Val Phe 
            20                  25                  30          


Cys Ser Ser Arg Asn Leu Thr Arg Leu Pro Asp Gly Val Pro Gly Gly 
        35                  40                  45              


Thr Gln Ala Leu Trp Leu Asp Gly Asn Asn Leu Ser Ser Val Pro Pro 
    50                  55                  60                  


Ala Ala Phe Gln Asn Leu Ser Ser Leu Gly Phe Leu Asn Leu Gln Gly 
65                  70                  75                  80  


Gly Gln Leu Gly Ser Leu Glu Pro Gln Ala Leu Leu Gly Leu Glu Asn 
                85                  90                  95      


Leu Cys His Leu His Leu Glu Arg Asn Gln Leu Arg Ser Leu Ala Leu 
            100                 105                 110         


Gly Thr Phe Ala His Thr Pro Ala Leu Ala Ser Leu Gly Leu Ser Asn 
        115                 120                 125             


Asn Arg Leu Ser Arg Leu Glu Asp Gly Leu Phe Glu Gly Leu Gly Ser 
    130                 135                 140                 


Leu Trp Asp Leu Asn Leu Gly Trp Asn Ser Leu Ala Val Leu Pro Asp 
145                 150                 155                 160 


Ala Ala Phe Arg Gly Leu Gly Ser Leu Arg Glu Leu Val Leu Ala Gly 
                165                 170                 175     


Asn Arg Leu Ala Tyr Leu Gln Pro Ala Leu Phe Ser Gly Leu Ala Glu 
            180                 185                 190         


Leu Arg Glu Leu Asp Leu Ser Arg Asn Ala Leu Arg Ala Ile Lys Ala 
        195                 200                 205             


Asn Val Phe Val Gln Leu Pro Arg Leu Gln Lys Leu Tyr Leu Asp Arg 
    210                 215                 220                 


Asn Leu Ile Ala Ala Val Ala Pro Gly Ala Phe Leu Gly Leu Lys Ala 
225                 230                 235                 240 


Leu Arg Trp Leu Asp Leu Ser His Asn Arg Val Ala Gly Leu Leu Glu 
                245                 250                 255     


Asp Thr Phe Pro Gly Leu Leu Gly Leu Arg Val Leu Arg Leu Ser His 
            260                 265                 270         


Asn Ala Ile Ala Ser Leu Arg Pro Arg Thr Phe Lys Asp Leu His Phe 
        275                 280                 285             


Leu Glu Glu Leu Gln Leu Gly His Asn Arg Ile Arg Gln Leu Ala Glu 
    290                 295                 300                 


Arg Ser Phe Glu Gly Leu Gly Gln Leu Glu Val Leu Thr Leu Asp His 
305                 310                 315                 320 


Asn Gln Leu Gln Glu Val Lys Ala Gly Ala Phe Leu Gly Leu Thr Asn 
                325                 330                 335     


Met Ala Val Met Asn Leu Ser Gly Asn Cys Leu Arg Asn Leu Pro Glu 
            340                 345                 350         


Gln Val Phe Arg Gly Leu Gly Lys Leu His Ser Leu His Leu Glu Gly 
        355                 360                 365             


Ser Cys Leu Gly Arg Ile Arg Pro His Thr Phe Thr Gly Leu Ser Gly 
    370                 375                 380                 


Leu Arg Arg Leu Phe Leu Lys Asp Asn Gly Leu Val Gly Ile Glu Glu 
385                 390                 395                 400 


Gln Ser Leu Trp Gly Leu Ala Glu Leu Leu Glu Leu Asp Leu Thr Ser 
                405                 410                 415     


Asn Gln Leu Thr His Leu Pro His Arg Leu Phe Gln Gly Leu Gly Lys 
            420                 425                 430         


Leu Glu Tyr Leu Leu Leu Ser Arg Asn Arg Leu Ala Glu Leu Pro Ala 
        435                 440                 445             


Asp Ala Leu Gly Pro Leu Gln Arg Ala Phe Trp Leu Asp Val Ser His 
    450                 455                 460                 


Asn Arg Leu Glu Ala Leu Pro Asn Ser Leu Leu Ala Pro Leu Gly Arg 
465                 470                 475                 480 


Leu Arg Tyr Leu Ser Leu Arg Asn Asn Ser Leu Arg Thr Phe Thr Pro 
                485                 490                 495     


Gln Pro Pro Gly Leu Glu Arg Leu Trp Leu Glu Gly Asn Pro Trp Asp 
            500                 505                 510         


Cys Gly Cys Pro Leu Lys Ala Leu Arg Asp Phe Ala Leu Gln Asn Pro 
        515                 520                 525             


Ser Ala Val Pro Arg Phe Val Gln Ala Ile Cys Glu Gly Asp Asp Cys 
    530                 535                 540                 


Gln Pro Pro Ala Tyr Thr Tyr Asn Asn Ile Thr Cys Ala Ser Pro Pro 
545                 550                 555                 560 


Glu Val Val Gly Leu Asp Leu Arg Asp Leu Ser Glu Ala His Phe Ala 
                565                 570                 575     


Pro Cys 
        


<210>  605
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  605

Ser Ser Ser Asp Thr Cys Gly Pro Cys Glu Pro Ala Ser Cys Pro Pro 
1               5                   10                  15      


Leu Pro Pro Leu Gly Cys Leu Leu Gly Glu Thr Arg Asp Ala Cys Gly 
            20                  25                  30          


Cys Cys Pro Met Cys Ala Arg Gly Glu Gly Glu Pro Cys Gly Gly Gly 
        35                  40                  45              


Gly Ala Gly Arg Gly Tyr Cys Ala Pro Gly Met Glu Cys Val Lys Ser 
    50                  55                  60                  


Arg Lys Arg Arg Lys Gly Lys Ala Gly Ala Ala Ala Gly Gly Pro Gly 
65                  70                  75                  80  


Val Ser Gly Val Cys Val Cys Lys Ser Arg Tyr Pro Val Cys Gly Ser 
                85                  90                  95      


Asp Gly Thr Thr Tyr Pro Ser Gly Cys Gln Leu Arg Ala Ala Ser Gln 
            100                 105                 110         


Arg Ala Glu Ser Arg Gly Glu Lys Ala Ile Thr Gln Val Ser Lys Gly 
        115                 120                 125             


Thr Cys Glu Gln Gly Pro Ser Ile Val Thr Pro Pro Lys Asp Ile Trp 
    130                 135                 140                 


Asn Val Thr Gly Ala Gln Val Tyr Leu Ser Cys Glu Val Ile Gly Ile 
145                 150                 155                 160 


Pro Thr Pro Val Leu Ile Trp Asn Lys Val Lys Arg Gly His Tyr Gly 
                165                 170                 175     


Val Gln Arg Thr Glu Leu Leu Pro Gly Asp Arg Asp Asn Leu Ala Ile 
            180                 185                 190         


Gln Thr Arg Gly Gly Pro Glu Lys His Glu Val Thr Gly Trp Val Leu 
        195                 200                 205             


Val Ser Pro Leu Ser Lys Glu Asp Ala Gly Glu Tyr Glu Cys His Ala 
    210                 215                 220                 


Ser Asn Ser Gln Gly Gln Ala Ser Ala Ser Ala Lys Ile Thr Val Val 
225                 230                 235                 240 


Asp Ala Leu His Glu Ile Pro Val Lys Lys Gly Glu Gly Ala Glu Leu 
                245                 250                 255     


<210>  606
<211>  253
<212>  PRT
<213>  Homo Sapiens

<400>  606

Leu Gly Ile Arg Asp Val Gly Gly Arg Arg Pro Lys Cys Gly Pro Cys 
1               5                   10                  15      


Arg Pro Glu Gly Cys Pro Ala Pro Ala Pro Cys Pro Ala Pro Gly Ile 
            20                  25                  30          


Ser Ala Leu Asp Glu Cys Gly Cys Cys Ala Arg Cys Leu Gly Ala Glu 
        35                  40                  45              


Gly Ala Ser Cys Gly Gly Arg Ala Gly Gly Arg Cys Gly Pro Gly Leu 
    50                  55                  60                  


Val Cys Ala Ser Gln Ala Ala Gly Ala Ala Pro Glu Gly Thr Gly Leu 
65                  70                  75                  80  


Cys Val Cys Ala Gln Arg Gly Thr Val Cys Gly Ser Asp Gly Arg Ser 
                85                  90                  95      


Tyr Pro Ser Val Cys Ala Leu Arg Leu Arg Ala Arg His Thr Pro Arg 
            100                 105                 110         


Ala His Pro Gly His Leu His Lys Ala Arg Asp Gly Pro Cys Glu Phe 
        115                 120                 125             


Ala Pro Val Val Val Val Pro Pro Arg Ser Val His Asn Val Thr Gly 
    130                 135                 140                 


Ala Gln Val Gly Leu Ser Cys Glu Val Arg Ala Val Pro Thr Pro Val 
145                 150                 155                 160 


Ile Thr Trp Arg Lys Val Thr Lys Ser Pro Glu Gly Thr Gln Ala Leu 
                165                 170                 175     


Glu Glu Leu Pro Gly Asp His Val Asn Ile Ala Val Gln Val Arg Gly 
            180                 185                 190         


Gly Pro Ser Asp His Glu Ala Thr Ala Trp Ile Leu Ile Asn Pro Leu 
        195                 200                 205             


Arg Lys Glu Asp Glu Gly Val Tyr Gln Cys His Ala Ala Asn Met Val 
    210                 215                 220                 


Gly Glu Ala Glu Ser His Ser Thr Val Thr Val Leu Asp Leu Ser Lys 
225                 230                 235                 240 


Tyr Arg Ser Phe His Phe Pro Ala Pro Asp Asp Arg Met 
                245                 250             


<210>  607
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  607

Ala Pro Val Ala Pro Met Thr Pro Tyr Leu Met Leu Cys Gln Pro His 
1               5                   10                  15      


Lys Arg Cys Gly Asp Lys Phe Tyr Asp Pro Leu Gln His Cys Cys Tyr 
            20                  25                  30          


Asp Asp Ala Val Val Pro Leu Ala Arg Thr Gln Thr Cys Gly Asn Cys 
        35                  40                  45              


Thr Phe Arg Val Cys Phe Glu Gln Cys Cys Pro Trp Thr Phe Met Val 
    50                  55                  60                  


Lys Leu Ile Asn Gln Asn Cys Asp Ser Ala Arg Thr Ser Asp Asp Arg 
65                  70                  75                  80  


Leu Cys Arg Ser Val Ser 
                85      


<210>  608
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  608

Pro Ala Gly Ser Glu Pro Trp Leu Cys Gln Pro Ala Pro Arg Cys Gly 
1               5                   10                  15      


Asp Lys Ile Tyr Asn Pro Leu Glu Gln Cys Cys Tyr Asn Asp Ala Ile 
            20                  25                  30          


Val Ser Leu Ser Glu Thr Arg Gln Cys Gly Pro Pro Cys Thr Phe Trp 
        35                  40                  45              


Pro Cys Phe Glu Leu Cys Cys Leu Asp Ser Phe Gly Leu Thr Asn Asp 
    50                  55                  60                  


Phe Val Val Lys Leu Lys Val Gln Gly Val Asn Ser Gln Cys His Ser 
65                  70                  75                  80  


Ser Pro Ile Ser Ser Lys Cys Glu Ser Arg Arg Arg Phe Pro 
                85                  90                  


<210>  609
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  609

Thr Thr Asp Ala Pro Val Gly Ser Gly Leu Trp Leu Cys Gln Pro Thr 
1               5                   10                  15      


Pro Arg Cys Gly Asn Lys Ile Tyr Asn Pro Ser Glu Gln Cys Cys Tyr 
            20                  25                  30          


Asp Asp Ala Ile Leu Ser Leu Lys Glu Thr Arg Arg Cys Gly Ser Thr 
        35                  40                  45              


Cys Thr Phe Trp Pro Cys Phe Glu Leu Cys Cys Pro Glu Ser Phe Gly 
    50                  55                  60                  


Pro Gln Gln Lys Phe Leu Val Lys Leu Arg Val Leu Gly Met Lys Ser 
65                  70                  75                  80  


Gln Cys His Leu Ser Pro Ile Ser Arg Ser Cys Thr Arg Asn Arg Arg 
                85                  90                  95      


His Val Leu Tyr Pro 
            100     


<210>  610
<211>  23
<212>  PRT
<213>  Homo Sapiens

<400>  610

Lys Ser Pro Cys Gly Asn Gln Ala Asn Val Leu Cys Ile Ser Arg Leu 
1               5                   10                  15      


Glu Phe Val Gln Tyr Gln Ser 
            20              


<210>  611
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  611

Leu Leu Arg Pro Thr Ala Ala Ser Gln Ser Arg Ala Leu Gly Pro Gly 
1               5                   10                  15      


Ala Pro Gly Gly Ser Ser Arg Ser Ser Leu Arg Ser Arg Trp Gly Arg 
            20                  25                  30          


Phe Leu Leu Gln Arg Gly Ser Trp Thr Gly Pro Arg Cys Trp Pro Arg 
        35                  40                  45              


Gly Phe Gln Ser Lys His Asn Ser Val Thr His Val Phe Gly Ser Gly 
    50                  55                  60                  


Thr Gln Leu Thr Val Leu Ser Gln Pro Lys Ala Thr Pro Ser Val Thr 
65                  70                  75                  80  


Leu Phe Pro Pro Ser Ser Glu Glu Leu Gln Ala Asn Lys Ala Thr Leu 
                85                  90                  95      


Val Cys Leu Met Asn Asp Phe Tyr Pro Gly Ile Leu Thr Val Thr Trp 
            100                 105                 110         


Lys Ala Asp Gly Thr Pro Ile Thr Gln Gly Val Glu Met Thr Thr Pro 
        115                 120                 125             


Ser Lys Gln Ser Asn Asn Lys Tyr Ala Ala Ser Ser Tyr Leu Ser Leu 
    130                 135                 140                 


Thr Pro Glu Gln Trp Arg Ser Arg Arg Ser Tyr Ser Cys Gln Val Met 
145                 150                 155                 160 


His Glu Gly Ser Thr Val Glu Lys Thr Val Ala Pro Ala Glu Cys Ser 
                165                 170                 175     


<210>  612
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  612

Val Leu Ala Gln Pro Pro Ser Val Ser Gly Ala Pro Gly Gln Thr Val 
1               5                   10                  15      


Thr Ile Ser Cys Thr Gly Ser Ser Thr Asn Ile Gly Ala Gly Tyr Ala 
            20                  25                  30          


Val His Trp Tyr Gln Gln Phe Pro Gly Ala Ala Pro Lys Val Leu Ile 
        35                  40                  45              


Tyr Gly Asn Tyr Asn Arg Pro Ser Gly Val Pro Asp Arg Phe Ser Gly 
    50                  55                  60                  


Ser Lys Ser Gly Thr Ser Ala Ser Leu Ala Ile Thr Gly Leu Gln Ala 
65                  70                  75                  80  


Glu Asp Glu Ala Asp Tyr Tyr Cys Gln Ser Tyr Asp Gly Ser Leu Ser 
                85                  90                  95      


Gly Ser Val Phe Gly Ala Gly Thr Lys Val Thr Val Leu Gly Gln Pro 
            100                 105                 110         


Lys Ala Asn Pro Thr Val Thr Leu Phe Pro Pro Ser Ser Glu Glu Leu 
        115                 120                 125             


Gln Ala Asn Lys Ala Thr Leu Val Cys Leu Ile Ser Asp Phe Tyr Pro 
    130                 135                 140                 


Gly Ala Val Thr Val Ala Trp Lys Ala Asp Gly Ser Pro Val Lys Ala 
145                 150                 155                 160 


Gly Val Glu Thr Thr Lys Pro Ser Lys Gln Ser Asn Asn Lys Tyr Ala 
                165                 170                 175     


Ala Ser Ser Tyr Leu Ser Leu Thr Pro Glu Gln Trp Lys Ser His Arg 
            180                 185                 190         


Ser Tyr Ser Cys Gln Val Thr His Glu Gly Ser Thr Val Glu Lys Thr 
        195                 200                 205             


Val Ala Pro Thr Glu Cys Ser 
    210                 215 


<210>  613
<211>  306
<212>  PRT
<213>  Homo Sapiens

<400>  613

Gln Ser Leu Glu Phe Asn Ser Pro Ala Asp Asn Tyr Thr Val Cys Glu 
1               5                   10                  15      


Gly Asp Asn Ala Thr Leu Ser Cys Phe Ile Asp Glu His Val Thr Arg 
            20                  25                  30          


Val Ala Trp Leu Asn Arg Ser Asn Ile Leu Tyr Ala Gly Asn Asp Arg 
        35                  40                  45              


Trp Thr Ser Asp Pro Arg Val Arg Leu Leu Ile Asn Thr Pro Glu Glu 
    50                  55                  60                  


Phe Ser Ile Leu Ile Thr Glu Val Gly Leu Gly Asp Glu Gly Leu Tyr 
65                  70                  75                  80  


Thr Cys Ser Phe Gln Thr Arg His Gln Pro Tyr Thr Thr Gln Val Tyr 
                85                  90                  95      


Leu Ile Val His Val Pro Ala Arg Ile Val Asn Ile Ser Ser Pro Val 
            100                 105                 110         


Thr Val Asn Glu Gly Gly Asn Val Asn Leu Leu Cys Leu Ala Val Gly 
        115                 120                 125             


Arg Pro Glu Pro Thr Val Thr Trp Arg Gln Leu Arg Asp Gly Phe Thr 
    130                 135                 140                 


Ser Glu Gly Glu Ile Leu Glu Ile Ser Asp Ile Gln Arg Gly Gln Ala 
145                 150                 155                 160 


Gly Glu Tyr Glu Cys Val Thr His Asn Gly Val Asn Ser Ala Pro Asp 
                165                 170                 175     


Ser Arg Arg Val Leu Val Thr Val Asn Tyr Pro Pro Thr Ile Thr Asp 
            180                 185                 190         


Val Thr Ser Ala Arg Thr Ala Leu Gly Arg Ala Ala Leu Leu Arg Cys 
        195                 200                 205             


Glu Ala Met Ala Val Pro Pro Ala Asp Phe Gln Trp Tyr Lys Asp Asp 
    210                 215                 220                 


Arg Leu Leu Ser Ser Gly Thr Ala Glu Gly Leu Lys Val Gln Thr Glu 
225                 230                 235                 240 


Arg Thr Arg Ser Met Leu Leu Phe Ala Asn Val Ser Ala Arg His Tyr 
                245                 250                 255     


Gly Asn Tyr Thr Cys Arg Ala Ala Asn Arg Leu Gly Ala Ser Ser Ala 
            260                 265                 270         


Ser Met Arg Leu Leu Arg Pro Gly Ser Leu Glu Asn Ser Ala Pro Arg 
        275                 280                 285             


Pro Pro Gly Leu Leu Ala Leu Leu Ser Ala Leu Gly Trp Leu Trp Trp 
    290                 295                 300                 


Arg Met 
305     


<210>  614
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  614

Met Thr Ser Ile Val Met Asp Pro Gln Pro Glu Leu Trp Ile Glu Ser 
1               5                   10                  15      


Asn Tyr Pro Gln Ala Pro Trp Glu Asn Ile Thr Leu Trp Cys Arg Ser 
            20                  25                  30          


Pro Ser Arg Ile Ser Ser Lys Phe Leu Leu Leu Lys Asp Lys Thr Gln 
        35                  40                  45              


Met Thr Trp Ile Arg Pro Ser His Lys Thr Phe Gln Val Ser Phe Leu 
    50                  55                  60                  


Ile Gly Ala Leu Thr Glu Ser Asn Ala Gly Leu Tyr Arg Cys Cys Tyr 
65                  70                  75                  80  


Trp Lys Glu Thr Gly Trp Ser Lys Pro Ser Lys Val Leu Glu Leu Glu 
                85                  90                  95      


Ala Pro Gly Gln Leu Pro Lys Pro Ile Phe Trp Ile Gln Ala Glu Thr 
            100                 105                 110         


Pro Ala Leu Pro Gly Cys Asn Val Asn Ile Leu Cys His Gly Trp Leu 
        115                 120                 125             


Gln Asp Leu Val Phe Met Leu Phe Lys Glu Gly Tyr Ala Glu Pro Val 
    130                 135                 140                 


Asp Tyr Gln Val Pro Thr Gly Thr Met Ala Ile Phe Ser Ile Asp Asn 
145                 150                 155                 160 


Leu Thr Pro Glu Asp Glu Gly Val Tyr Ile Cys Arg Thr His Ile Gln 
                165                 170                 175     


Met Leu Pro Thr Leu Trp Ser Glu Pro Ser Asn Pro Leu Lys Leu Val 
            180                 185                 190         


Val Ala Gly Leu Tyr Pro Lys Pro Thr Leu Thr Ala His Pro Gly Pro 
        195                 200                 205             


Ile Met Ala Pro Gly Glu Ser Leu Asn Leu Arg Cys Gln Gly Pro Ile 
    210                 215                 220                 


Tyr Gly Met Thr Phe Ala Leu Met Arg Val Glu Asp Leu Glu Lys Ser 
225                 230                 235                 240 


Phe Tyr His Lys Lys Thr Ile Lys Asn Glu Ala Asn Phe Phe Phe Gln 
                245                 250                 255     


Ser Leu Lys Ile Gln Asp Thr Gly His Tyr Leu Cys Phe Tyr Tyr Asp 
            260                 265                 270         


Ala Ser Tyr Arg Gly Ser Leu Leu Ser Asp Val Leu Lys Ile Trp Val 
        275                 280                 285             


Thr Asp Thr Phe Pro Lys Thr Trp Leu Leu Ala Arg Pro Ser Ala Val 
    290                 295                 300                 


Val Gln Met Gly Gln Asn Val Ser Leu Arg Cys Arg Gly Pro Val Asp 
305                 310                 315                 320 


Gly Val Gly Leu Ala Leu Tyr Lys Lys Gly Glu Asp Lys Pro Leu Gln 
                325                 330                 335     


Phe Leu Asp Ala Thr Ser Ile Asp Asp Asn Thr Ser Phe Phe Leu Asn 
            340                 345                 350         


Asn Val Thr Tyr Ser Asp Thr Gly Ile Tyr Ser Cys His Tyr Leu Leu 
        355                 360                 365             


Thr Trp Lys Thr Ser Ile Arg Met Pro Ser His Asn Thr Val Glu Leu 
    370                 375                 380                 


Met Val Val Asp Lys Pro Pro Lys Pro Ser Leu Ser Ala Trp Pro Ser 
385                 390                 395                 400 


Thr Val Phe Lys Leu Gly Lys Ala Ile Thr Leu Gln Cys Arg Val Ser 
                405                 410                 415     


His Pro Val Leu Glu Phe Ser Leu Glu Trp Glu Glu Arg Glu Thr Phe 
            420                 425                 430         


Gln Lys Phe Ser Val Asn Gly Asp Phe Ile Ile Ser Asn Val Asp Gly 
        435                 440                 445             


Lys Gly Thr Gly Thr Tyr Ser Cys Ser Tyr Arg Val Glu Thr His Pro 
    450                 455                 460                 


Asn Ile Trp Ser His Arg Ser Glu Pro Leu Lys Leu Met Gly Pro Ala 
465                 470                 475                 480 


Gly Tyr Leu Thr Trp Asn Tyr Val Leu Asn 
                485                 490 


<210>  615
<211>  390
<212>  PRT
<213>  Homo Sapiens

<400>  615

Pro Pro Leu Ile Asn Gly Leu Tyr Thr Asn Arg Thr Val Ile Lys Ala 
1               5                   10                  15      


Thr Ala Val Arg His Ser Lys Lys His Phe Asp Cys Arg Ala Glu Gly 
            20                  25                  30          


Thr Pro Ser Pro Glu Val Met Trp Ile Met Pro Asp Asn Ile Phe Leu 
        35                  40                  45              


Thr Ala Pro Tyr Tyr Gly Ser Arg Ile Thr Val His Lys Asn Gly Thr 
    50                  55                  60                  


Leu Glu Ile Arg Asn Val Arg Leu Ser Asp Ser Ala Asp Phe Ile Cys 
65                  70                  75                  80  


Val Ala Arg Asn Glu Gly Gly Glu Ser Val Leu Val Val Gln Leu Glu 
                85                  90                  95      


Val Leu Glu Met Leu Arg Arg Pro Thr Phe Arg Asn Pro Phe Asn Glu 
            100                 105                 110         


Lys Ile Val Ala Gln Leu Gly Lys Ser Thr Ala Leu Asn Cys Ser Val 
        115                 120                 125             


Asp Gly Asn Pro Pro Pro Glu Ile Ile Trp Ile Leu Pro Asn Gly Thr 
    130                 135                 140                 


Arg Phe Ser Asn Gly Pro Gln Ser Tyr Gln Tyr Leu Ile Ala Ser Asn 
145                 150                 155                 160 


Gly Ser Phe Ile Ile Ser Lys Thr Thr Arg Glu Asp Ala Gly Lys Tyr 
                165                 170                 175     


Arg Cys Ala Ala Arg Asn Lys Val Gly Tyr Ile Glu Lys Leu Val Ile 
            180                 185                 190         


Leu Glu Ile Gly Gln Lys Pro Val Ile Leu Thr Tyr Ala Pro Gly Thr 
        195                 200                 205             


Val Lys Gly Ile Ser Gly Glu Ser Leu Ser Leu His Cys Val Ser Asp 
    210                 215                 220                 


Gly Ile Pro Lys Pro Asn Ile Lys Trp Thr Met Pro Ser Gly Tyr Val 
225                 230                 235                 240 


Val Asp Arg Pro Gln Ile Asn Gly Lys Tyr Ile Leu His Asp Asn Gly 
                245                 250                 255     


Thr Leu Val Ile Lys Glu Ala Thr Ala Tyr Asp Arg Gly Asn Tyr Ile 
            260                 265                 270         


Cys Lys Ala Gln Asn Ser Val Gly His Thr Leu Ile Thr Val Pro Val 
        275                 280                 285             


Met Ile Val Ala Tyr Pro Pro Arg Ile Thr Asn Arg Pro Pro Arg Ser 
    290                 295                 300                 


Ile Val Thr Arg Thr Gly Ala Ala Phe Gln Leu His Cys Val Ala Leu 
305                 310                 315                 320 


Gly Val Pro Lys Pro Glu Ile Thr Trp Glu Met Pro Asp His Ser Leu 
                325                 330                 335     


Leu Ser Thr Ala Ser Lys Glu Arg Thr His Gly Ser Glu Gln Leu His 
            340                 345                 350         


Leu Gln Gly Thr Leu Val Ile Gln Asn Pro Gln Thr Ser Asp Ser Gly 
        355                 360                 365             


Ile Tyr Lys Cys Thr Ala Lys Asn Pro Leu Gly Ser Asp Tyr Ala Ala 
    370                 375                 380                 


Thr Tyr Ile Gln Val Ile 
385                 390 


<210>  616
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  616

Leu Glu Val Ser Glu Ser Pro Gly Ser Ile Gln Val Ala Arg Gly Gln 
1               5                   10                  15      


Thr Ala Val Leu Pro Cys Thr Phe Thr Thr Ser Ala Ala Leu Ile Asn 
            20                  25                  30          


Leu Asn Val Ile Trp Met Val Thr Pro Leu Ser Asn Ala Asn Gln Pro 
        35                  40                  45              


Glu Gln Val Ile Leu Tyr Gln Gly Gly Gln Met Phe Asp Gly Ala Pro 
    50                  55                  60                  


Arg Phe His Gly Arg Val Gly Phe Thr Gly Thr Met Pro Ala Thr Asn 
65                  70                  75                  80  


Val Ser Ile Phe Ile Asn Asn Thr Gln Leu Ser Asp Thr Gly Thr Tyr 
                85                  90                  95      


Gln Cys Leu Val Asn Asn Leu Pro Asp Ile Gly Gly Arg Asn Ile Gly 
            100                 105                 110         


Val Thr Gly Leu Thr Val Leu Val Pro Pro Ser Ala Pro His Cys Gln 
        115                 120                 125             


Ile Gln Gly Ser Gln Asp Ile Gly Ser Asp Val Ile Leu Leu Cys Ser 
    130                 135                 140                 


Ser Glu Glu Gly Ile Pro Arg Pro Thr Tyr Leu Trp Glu Lys Leu Asp 
145                 150                 155                 160 


Asn Thr Leu Lys Leu Pro Pro Thr Ala Thr Gln Asp Gln Val Gln Gly 
                165                 170                 175     


Thr Val Thr Ile Arg Asn Ile Ser Ala Leu Ser Ser Gly Leu Tyr Gln 
            180                 185                 190         


Cys Val Ala Ser Asn Ala Ile Gly Thr Ser Thr Cys Leu Leu Asp Leu 
        195                 200                 205             


Gln Val Ile Ser Pro Gln Pro Arg Asn Ile Gly 
    210                 215                 


<210>  617
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  617

Tyr Leu Thr Val Asn Ile Glu Pro Leu Pro Pro Val Val Ala Gly Asp 
1               5                   10                  15      


Ala Val Thr Leu Lys Cys Asn Phe Lys Thr Asp Gly Arg Met Arg Glu 
            20                  25                  30          


Ile Val Trp Tyr Arg Val Thr Asp Gly Gly Thr Ile Lys Gln Lys Ile 
        35                  40                  45              


Phe Thr Phe Asp Ala Met Phe Ser Thr Asn Tyr Ser His Met Glu Asn 
    50                  55                  60                  


Tyr Arg Lys Arg Glu Asp Leu Val Tyr Gln Ser Thr Val Arg Leu Pro 
65                  70                  75                  80  


Glu Val Arg Ile Ser Asp Asn Gly Pro Tyr Glu Cys His Val Gly Ile 
                85                  90                  95      


Tyr Asp Arg Ala Thr Arg Glu Lys Val Val Leu Ala Ser Gly Asn Ile 
            100                 105                 110         


Phe Leu Asn Val Met Ala Pro Pro Thr Ser Ile Glu Val Val Ala Ala 
        115                 120                 125             


Asp Thr Pro Ala Pro Phe Ser Arg Tyr Gln Ala Gln Asn Phe Thr Leu 
    130                 135                 140                 


Val Cys Ile Val Ser Gly Gly Lys Pro Ala Pro Met Val Tyr Phe Lys 
145                 150                 155                 160 


Arg Asp Gly Glu Pro Ile Asp Ala Val Pro Leu Ser Glu Pro Pro Ala 
                165                 170                 175     


Ala Ser Ser Gly Pro Leu Gln Asp Ser Arg Pro Phe Arg Ser Leu Leu 
            180                 185                 190         


His Arg Asp Leu Asp Asp Thr Lys Met Gln Lys Ser Leu Ser Leu Leu 
        195                 200                 205             


Asp Ala Glu Asn Arg Gly Gly Arg Pro Tyr Thr Glu Arg Pro Ser Arg 
    210                 215                 220                 


Gly Leu Thr Pro Asp Pro Asn Ile Leu Leu Gln Pro Thr Thr Glu Asn 
225                 230                 235                 240 


Ile Pro Glu Thr Val Val Ser Arg Glu Phe Pro Arg Trp Val His Ser 
                245                 250                 255     


Ala Glu Pro Thr Tyr Phe Leu Arg His Ser Arg Thr Pro Ser Ser Asp 
            260                 265                 270         


Gly Thr Val Glu Val Arg Ala Leu Leu Thr Trp Thr Leu Asn Pro Gln 
        275                 280                 285             


Ile Asp Asn Glu Ala Leu Phe Ser Cys Glu Val Lys His Pro Ala Leu 
    290                 295                 300                 


Ser Met Pro Met Gln Ala Glu Val Thr Leu Val Ala Pro Lys Gly Pro 
305                 310                 315                 320 


Lys Ile Val Met Thr Pro Ser Arg Ala Arg Val Gly Asp Thr Val Arg 
                325                 330                 335     


Ile Leu Val His Gly Phe Gln Asn Glu Val Phe Pro Glu Pro Met Phe 
            340                 345                 350         


Thr Trp Thr Arg Val Gly Ser Arg Leu Leu Asp Gly Ser Ala Glu Phe 
        355                 360                 365             


Asp Gly Lys Glu Leu Val Leu Glu Arg Val Pro Ala Glu Leu Asn Gly 
    370                 375                 380                 


Ser Met Tyr Arg Cys Thr Ala Gln Asn Pro Leu Gly Ser Thr Asp Thr 
385                 390                 395                 400 


His Thr Arg Leu Ile Val Phe Glu Asn Pro Asn Ile Pro Arg Gly Thr 
                405                 410                 415     


Glu Asp Ser Asn 
            420 


<210>  618
<211>  1106
<212>  PRT
<213>  Homo Sapiens

<400>  618

Gln Arg Gln Val Thr Val Gln Glu Gly Pro Leu Tyr Arg Thr Glu Gly 
1               5                   10                  15      


Ser His Ile Thr Ile Trp Cys Asn Val Ser Gly Tyr Gln Gly Pro Ser 
            20                  25                  30          


Glu Gln Asn Phe Gln Trp Ser Ile Tyr Leu Pro Ser Ser Pro Glu Arg 
        35                  40                  45              


Glu Val Gln Ile Val Ser Thr Met Asp Ser Ser Phe Pro Tyr Ala Ile 
    50                  55                  60                  


Tyr Thr Gln Arg Val Arg Gly Gly Lys Ile Phe Ile Glu Arg Val Gln 
65                  70                  75                  80  


Gly Asn Ser Thr Leu Leu His Ile Thr Asp Leu Gln Ala Arg Asp Ala 
                85                  90                  95      


Gly Glu Tyr Glu Cys His Thr Pro Ser Thr Asp Lys Gln Tyr Phe Gly 
            100                 105                 110         


Ser Tyr Ser Ala Lys Met Asn Leu Val Val Ile Pro Asp Ser Leu Gln 
        115                 120                 125             


Thr Thr Ala Met Pro Gln Thr Leu His Arg Val Glu Gln Asp Pro Leu 
    130                 135                 140                 


Glu Leu Thr Cys Glu Val Ala Ser Glu Thr Ile Gln His Ser His Leu 
145                 150                 155                 160 


Ser Val Ala Trp Leu Arg Gln Lys Val Gly Glu Lys Pro Val Glu Val 
                165                 170                 175     


Ile Ser Leu Ser Arg Asp Phe Met Leu His Ser Ser Ser Glu Tyr Ala 
            180                 185                 190         


Gln Arg Gln Ser Leu Gly Glu Val Arg Leu Asp Lys Leu Gly Arg Thr 
        195                 200                 205             


Thr Phe Arg Leu Thr Ile Phe His Leu Gln Pro Ser Asp Gln Gly Glu 
    210                 215                 220                 


Phe Tyr Cys Glu Ala Ala Glu Trp Ile Gln Asp Pro Asp Gly Ser Trp 
225                 230                 235                 240 


Tyr Ala Met Thr Arg Lys Arg Ser Glu Gly Ala Val Val Asn Val Gln 
                245                 250                 255     


Pro Thr Asp Lys Glu Phe Thr Val Arg Leu Glu Thr Glu Lys Arg Leu 
            260                 265                 270         


His Thr Val Gly Glu Pro Val Glu Phe Arg Cys Ile Leu Glu Ala Gln 
        275                 280                 285             


Asn Val Pro Asp Arg Tyr Phe Ala Val Ser Trp Ala Phe Asn Ser Ser 
    290                 295                 300                 


Leu Ile Ala Thr Met Gly Pro Asn Ala Val Pro Val Leu Asn Ser Glu 
305                 310                 315                 320 


Phe Ala His Arg Glu Ala Arg Gly Gln Leu Lys Val Ala Lys Glu Ser 
                325                 330                 335     


Asp Ser Val Phe Val Leu Lys Ile Tyr His Leu Arg Gln Glu Asp Ser 
            340                 345                 350         


Gly Lys Tyr Asn Cys Arg Val Thr Glu Arg Glu Lys Thr Val Thr Gly 
        355                 360                 365             


Glu Phe Ile Asp Lys Glu Ser Lys Arg Pro Lys Asn Ile Pro Ile Ile 
    370                 375                 380                 


Val Leu Pro Leu Lys Ser Ser Ile Ser Val Glu Val Ala Ser Asn Ala 
385                 390                 395                 400 


Ser Val Ile Leu Glu Gly Glu Asp Leu Arg Phe Ser Cys Ser Val Arg 
                405                 410                 415     


Thr Ala Gly Arg Pro Gln Gly Arg Phe Ser Val Ile Trp Gln Leu Val 
            420                 425                 430         


Asp Arg Gln Asn Arg Arg Ser Asn Ile Met Trp Leu Asp Arg Asp Gly 
        435                 440                 445             


Thr Val Gln Pro Gly Ser Ser Tyr Trp Glu Arg Ser Ser Phe Gly Gly 
    450                 455                 460                 


Val Gln Met Glu Gln Val Gln Pro Asn Ser Phe Ser Leu Gly Ile Phe 
465                 470                 475                 480 


Asn Ser Arg Lys Glu Asp Glu Gly Gln Tyr Glu Cys His Val Thr Glu 
                485                 490                 495     


Trp Val Arg Ala Val Asp Gly Glu Trp Gln Ile Val Gly Glu Arg Arg 
            500                 505                 510         


Ala Ser Thr Pro Ile Ser Ile Thr Ala Leu Glu Met Gly Phe Ala Val 
        515                 520                 525             


Thr Ala Ile Ser Arg Thr Pro Gly Val Thr Tyr Ser Asp Ser Phe Asp 
    530                 535                 540                 


Leu Gln Cys Ile Ile Lys Pro His Tyr Pro Ala Trp Val Pro Val Ser 
545                 550                 555                 560 


Val Thr Trp Arg Phe Gln Pro Val Gly Thr Val Glu Phe His Asp Leu 
                565                 570                 575     


Val Thr Phe Thr Arg Asp Gly Gly Val Gln Trp Gly Asp Arg Ser Ser 
            580                 585                 590         


Ser Phe Arg Thr Arg Thr Ala Ile Glu Lys Ala Glu Ser Gly Asn Asn 
        595                 600                 605             


Val Arg Leu Ser Ile Ser Arg Ala Ser Asp Thr Glu Ala Gly Lys Tyr 
    610                 615                 620                 


Gln Cys Val Ala Glu Leu Trp Arg Lys Asn Tyr Asn Asn Thr Trp Thr 
625                 630                 635                 640 


Arg Leu Ala Glu Arg Thr Ser Asn Leu Leu Glu Ile Arg Val Leu Gln 
                645                 650                 655     


Pro Val Thr Lys Leu Gln Val Ser Lys Ser Lys Arg Thr Leu Thr Leu 
            660                 665                 670         


Val Glu Asn Lys Pro Ile Gln Leu Asn Cys Ser Val Lys Ser Gln Thr 
        675                 680                 685             


Ser Gln Asn Ser His Phe Ala Val Leu Trp Tyr Val His Lys Pro Ser 
    690                 695                 700                 


Asp Ala Asp Gly Lys Leu Ile Leu Lys Thr Thr His Asn Ser Ala Phe 
705                 710                 715                 720 


Glu Tyr Gly Thr Tyr Ala Glu Glu Glu Gly Leu Arg Ala Arg Leu Gln 
                725                 730                 735     


Phe Glu Arg His Val Ser Gly Gly Leu Phe Ser Leu Thr Val Gln Arg 
            740                 745                 750         


Ala Glu Val Ser Asp Ser Gly Ser Tyr Tyr Cys His Val Glu Glu Trp 
        755                 760                 765             


Leu Leu Ser Pro Asn Tyr Ala Trp Tyr Lys Leu Ala Glu Glu Val Ser 
    770                 775                 780                 


Gly Arg Thr Glu Val Thr Val Lys Gln Pro Asp Ser Arg Leu Arg Leu 
785                 790                 795                 800 


Ser Gln Ala Gln Gly Asn Leu Ser Val Leu Glu Thr Arg Gln Val Gln 
                805                 810                 815     


Leu Glu Cys Val Val Leu Asn Arg Thr Ser Ile Thr Ser Gln Leu Met 
            820                 825                 830         


Val Glu Trp Phe Val Trp Lys Pro Asn His Pro Glu Arg Glu Thr Val 
        835                 840                 845             


Ala Arg Leu Ser Arg Asp Ala Thr Phe His Tyr Gly Glu Gln Ala Ala 
    850                 855                 860                 


Lys Asn Asn Leu Lys Gly Arg Leu His Leu Glu Ser Pro Ser Pro Gly 
865                 870                 875                 880 


Val Tyr Arg Leu Phe Ile Gln Asn Val Ala Val Gln Asp Ser Gly Thr 
                885                 890                 895     


Tyr Ser Cys His Val Glu Glu Trp Leu Pro Ser Pro Ser Gly Met Trp 
            900                 905                 910         


Tyr Lys Arg Ala Glu Asp Thr Ala Gly Gln Thr Ala Leu Thr Val Met 
        915                 920                 925             


Arg Pro Asp Ala Ser Leu Gln Val Asp Thr Val Val Pro Asn Ala Thr 
    930                 935                 940                 


Val Ser Glu Lys Ala Ala Phe Gln Leu Asp Cys Ser Ile Val Ser Arg 
945                 950                 955                 960 


Ser Ser Gln Asp Ser Arg Phe Ala Val Ala Trp Tyr Ser Leu Arg Thr 
                965                 970                 975     


Lys Ala Gly Gly Lys Arg Ser Ser Pro Gly Leu Glu Glu Gln Glu Glu 
            980                 985                 990         


Glu Arg Glu Glu Glu Glu Glu Glu  Glu Glu Asp Asp Asp  Asp Asp Asp 
        995                 1000                 1005             


Pro Thr  Glu Arg Thr Ala Leu  Leu Ser Val Gly Pro  Asp Ala Val 
    1010                 1015                 1020             


Phe Gly  Pro Glu Gly Ser Pro  Trp Glu Gly Arg Leu  Arg Phe Gln 
    1025                 1030                 1035             


Arg Leu  Ser Pro Val Leu Tyr  Arg Leu Thr Val Leu  Gln Ala Ser 
    1040                 1045                 1050             


Pro Gln  Asp Thr Gly Asn Tyr  Ser Cys His Val Glu  Glu Trp Leu 
    1055                 1060                 1065             


Pro Ser  Pro Gln Lys Glu Trp  Tyr Arg Leu Thr Glu  Glu Glu Ser 
    1070                 1075                 1080             


Ala Pro  Ile Gly Ile Arg Val  Leu Asp Thr Ser Pro  Thr Leu Gln 
    1085                 1090                 1095             


Ser Ile  Ile Cys Ser Asn Asp  Ala 
    1100                 1105     


<210>  619
<211>  306
<212>  PRT
<213>  Homo Sapiens

<400>  619

Asn Leu Ser Gln Asp Asp Ser Gln Pro Trp Thr Ser Asp Glu Thr Val 
1               5                   10                  15      


Val Ala Gly Gly Thr Val Val Leu Lys Cys Gln Val Lys Asp His Glu 
            20                  25                  30          


Asp Ser Ser Leu Gln Trp Ser Asn Pro Ala Gln Gln Thr Leu Tyr Phe 
        35                  40                  45              


Gly Glu Lys Arg Ala Leu Arg Asp Asn Arg Ile Gln Leu Val Thr Ser 
    50                  55                  60                  


Thr Pro His Glu Leu Ser Ile Ser Ile Ser Asn Val Ala Leu Ala Asp 
65                  70                  75                  80  


Glu Gly Glu Tyr Thr Cys Ser Ile Phe Thr Met Pro Val Arg Thr Ala 
                85                  90                  95      


Lys Ser Leu Val Thr Val Leu Gly Ile Pro Gln Lys Pro Ile Ile Thr 
            100                 105                 110         


Gly Tyr Lys Ser Ser Leu Arg Glu Lys Asp Thr Ala Thr Leu Asn Cys 
        115                 120                 125             


Gln Ser Ser Gly Ser Lys Pro Ala Ala Arg Leu Thr Trp Arg Lys Gly 
    130                 135                 140                 


Asp Gln Glu Leu His Gly Glu Pro Thr Arg Ile Gln Glu Asp Pro Asn 
145                 150                 155                 160 


Gly Lys Thr Phe Thr Val Ser Ser Ser Val Thr Phe Gln Val Thr Arg 
                165                 170                 175     


Glu Asp Asp Gly Ala Ser Ile Val Cys Ser Val Asn His Glu Ser Leu 
            180                 185                 190         


Lys Gly Ala Asp Arg Ser Thr Ser Gln Arg Ile Glu Val Leu Tyr Thr 
        195                 200                 205             


Pro Thr Ala Met Ile Arg Pro Asp Pro Pro His Pro Arg Glu Gly Gln 
    210                 215                 220                 


Lys Leu Leu Leu His Cys Glu Gly Arg Gly Asn Pro Val Pro Gln Gln 
225                 230                 235                 240 


Tyr Leu Trp Glu Lys Glu Gly Ser Val Pro Pro Leu Lys Met Thr Gln 
                245                 250                 255     


Glu Ser Ala Leu Ile Phe Pro Phe Leu Asn Lys Ser Asp Ser Gly Thr 
            260                 265                 270         


Tyr Gly Cys Thr Ala Thr Ser Asn Met Gly Ser Tyr Lys Ala Tyr Tyr 
        275                 280                 285             


Thr Leu Asn Val Asn Asp Pro Ser Pro Val Pro Ser Ser Ser Ser Thr 
    290                 295                 300                 


Tyr His 
305     


<210>  620
<211>  304
<212>  PRT
<213>  Homo Sapiens

<400>  620

Pro Gly Ala Gly Gln Glu Val Gln Thr Glu Asn Val Thr Val Ala Glu 
1               5                   10                  15      


Gly Gly Val Ala Glu Ile Thr Cys Arg Leu His Gln Tyr Asp Gly Ser 
            20                  25                  30          


Ile Val Val Ile Gln Asn Pro Ala Arg Gln Thr Leu Phe Phe Asn Gly 
        35                  40                  45              


Thr Arg Ala Leu Lys Asp Glu Arg Phe Gln Leu Glu Glu Phe Ser Pro 
    50                  55                  60                  


Arg Arg Val Arg Ile Arg Leu Ser Asp Ala Arg Leu Glu Asp Glu Gly 
65                  70                  75                  80  


Gly Tyr Phe Cys Gln Leu Tyr Thr Glu Asp Thr His His Gln Ile Ala 
                85                  90                  95      


Thr Leu Thr Val Leu Val Ala Pro Glu Asn Pro Val Val Glu Val Arg 
            100                 105                 110         


Glu Gln Ala Val Glu Gly Gly Glu Val Glu Leu Ser Cys Leu Val Pro 
        115                 120                 125             


Arg Ser Arg Pro Ala Ala Thr Leu Arg Trp Tyr Arg Asp Arg Lys Glu 
    130                 135                 140                 


Leu Lys Gly Val Ser Ser Ser Gln Glu Asn Gly Lys Val Trp Ser Val 
145                 150                 155                 160 


Ala Ser Thr Val Arg Phe Arg Val Asp Arg Lys Asp Asp Gly Gly Ile 
                165                 170                 175     


Ile Ile Cys Glu Ala Gln Asn Gln Ala Leu Pro Ser Gly His Ser Lys 
            180                 185                 190         


Gln Thr Gln Tyr Val Leu Asp Val Gln Tyr Ser Pro Thr Ala Arg Ile 
        195                 200                 205             


His Ala Ser Gln Ala Val Val Arg Glu Gly Asp Thr Leu Val Leu Thr 
    210                 215                 220                 


Cys Ala Val Thr Gly Asn Pro Arg Pro Asn Gln Ile Arg Trp Asn Arg 
225                 230                 235                 240 


Gly Asn Glu Ser Leu Pro Glu Arg Ala Glu Ala Val Gly Glu Thr Leu 
                245                 250                 255     


Thr Leu Pro Gly Leu Val Ser Ala Asp Asn Gly Thr Tyr Thr Cys Glu 
            260                 265                 270         


Ala Ser Asn Lys His Gly His Ala Arg Ala Leu Tyr Val Leu Val Val 
        275                 280                 285             


Tyr Asp Pro Gly Ala Val Val Glu Ala Gln Thr Ser Val Pro Tyr Ala 
    290                 295                 300                 


<210>  621
<211>  266
<212>  PRT
<213>  Homo Sapiens

<400>  621

Met Gly Gln Lys Glu Arg Ser Thr Ala Asp Thr Leu Pro Asp Leu Glu 
1               5                   10                  15      


Glu Trp Lys Ser Ala Ala Gly Leu Arg Trp Trp Gln Thr Ala Val Val 
            20                  25                  30          


Asp Gly Ser Gly Ser Gly Asn Glu Val Ile Glu Gly Pro Gln Asn Ala 
        35                  40                  45              


Arg Val Leu Lys Gly Ser Gln Ala Arg Phe Asn Cys Thr Val Ser Gln 
    50                  55                  60                  


Gly Trp Lys Leu Ile Met Trp Ala Leu Ser Asp Met Val Val Leu Ser 
65                  70                  75                  80  


Val Arg Pro Met Glu Pro Ile Ile Thr Asn Asp Arg Phe Thr Ser Gln 
                85                  90                  95      


Arg Tyr Asp Gln Gly Gly Asn Phe Thr Ser Glu Met Ile Ile His Asn 
            100                 105                 110         


Val Glu Pro Ser Asp Ser Gly Asn Ile Arg Cys Ser Leu Gln Asn Ser 
        115                 120                 125             


Arg Leu His Gly Ser Ala Tyr Leu Thr Val Gln Val Met Gly Glu Leu 
    130                 135                 140                 


Phe Ile Pro Ser Val Asn Leu Val Val Ala Glu Asn Glu Pro Cys Glu 
145                 150                 155                 160 


Val Thr Cys Leu Pro Ser His Trp Thr Arg Leu Pro Asp Ile Ser Trp 
                165                 170                 175     


Glu Leu Gly Leu Leu Val Ser His Ser Ser Tyr Tyr Phe Val Pro Glu 
            180                 185                 190         


Pro Ser Asp Leu Gln Ser Ala Val Ser Ile Leu Ala Leu Thr Pro Gln 
        195                 200                 205             


Ser Asn Gly Thr Leu Thr Cys Val Ala Thr Trp Lys Ser Leu Lys Ala 
    210                 215                 220                 


Arg Lys Ser Ala Thr Val Asn Leu Thr Val Ile Arg Cys Pro Gln Asp 
225                 230                 235                 240 


Thr Gly Gly Gly Ile Asn Ile Pro Gly Val Leu Ser Ser Leu Pro Ser 
                245                 250                 255     


Leu Gly Phe Ser Leu Pro Thr Trp Gly Lys 
            260                 265     


<210>  622
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  622

Cys Thr Leu Ser Val Thr Gln Pro Trp Tyr Leu Glu Val Asp Tyr Thr 
1               5                   10                  15      


His Glu Ala Val Thr Ile Lys Cys Thr Phe Ser Ala Thr Gly Cys Pro 
            20                  25                  30          


Ser Glu Gln Pro Thr Cys Leu Trp Phe Arg Tyr Gly Ala His Arg Pro 
        35                  40                  45              


Glu Asn Leu Cys Leu Asp Gly Cys Lys Ser Glu Ala Asp Lys Phe Thr 
    50                  55                  60                  


Val Arg Glu Ala Leu Lys Glu Asn Gln Val Ser Leu Thr Val Asn Arg 
65                  70                  75                  80  


Val Thr Ser Asn Asp Ser Ala Ile Tyr Ile Cys Gly Ile Ala Phe Pro 
                85                  90                  95      


Ser Val Pro Glu Ala Arg Ala Lys Gln Thr Gly Gly Gly Thr Thr Leu 
            100                 105                 110         


Val Val Arg Glu Ile Lys Leu Leu Ser Lys Glu Leu Arg Ser 
        115                 120                 125     


<210>  623
<211>  552
<212>  PRT
<213>  Homo Sapiens

<400>  623

Arg Glu Val Leu Val Pro Glu Gly Pro Leu Tyr Arg Val Ala Gly Thr 
1               5                   10                  15      


Ala Val Ser Ile Ser Cys Asn Val Thr Gly Tyr Glu Gly Pro Ala Gln 
            20                  25                  30          


Gln Asn Phe Glu Trp Phe Leu Tyr Arg Pro Glu Ala Pro Asp Thr Ala 
        35                  40                  45              


Leu Gly Ile Val Ser Thr Lys Asp Thr Gln Phe Ser Tyr Ala Val Phe 
    50                  55                  60                  


Lys Ser Arg Val Val Ala Gly Glu Val Gln Val Gln Arg Leu Gln Gly 
65                  70                  75                  80  


Asp Ala Val Val Leu Lys Ile Ala Arg Leu Gln Ala Gln Asp Ala Gly 
                85                  90                  95      


Ile Tyr Glu Cys His Thr Pro Ser Thr Asp Thr Arg Tyr Leu Gly Ser 
            100                 105                 110         


Tyr Ser Gly Lys Val Glu Leu Arg Val Leu Pro Asp Val Leu Gln Val 
        115                 120                 125             


Ser Ala Ala Pro Pro Gly Pro Arg Gly Arg Gln Ala Pro Thr Ser Pro 
    130                 135                 140                 


Pro Arg Met Thr Val His Glu Gly Gln Glu Leu Ala Leu Gly Cys Leu 
145                 150                 155                 160 


Ala Arg Thr Ser Thr Gln Lys His Thr His Leu Ala Val Ser Phe Gly 
                165                 170                 175     


Arg Ser Val Pro Glu Ala Pro Val Gly Arg Ser Thr Leu Gln Glu Val 
            180                 185                 190         


Val Gly Ile Arg Ser Asp Leu Ala Val Glu Ala Gly Ala Pro Tyr Ala 
        195                 200                 205             


Glu Arg Leu Ala Ala Gly Glu Leu Arg Leu Gly Lys Glu Gly Thr Asp 
    210                 215                 220                 


Arg Tyr Arg Met Val Val Gly Gly Ala Gln Ala Gly Asp Ala Gly Thr 
225                 230                 235                 240 


Tyr His Cys Thr Ala Ala Glu Trp Ile Gln Asp Pro Asp Gly Ser Trp 
                245                 250                 255     


Ala Gln Ile Ala Glu Lys Arg Ala Val Leu Ala His Val Asp Val Gln 
            260                 265                 270         


Thr Leu Ser Ser Gln Leu Ala Val Thr Val Gly Pro Gly Glu Arg Arg 
        275                 280                 285             


Ile Gly Pro Gly Glu Pro Leu Glu Leu Leu Cys Asn Val Ser Gly Ala 
    290                 295                 300                 


Leu Pro Pro Ala Gly Arg His Ala Ala Tyr Ser Val Gly Trp Glu Met 
305                 310                 315                 320 


Ala Pro Ala Gly Ala Pro Gly Pro Gly Arg Leu Val Ala Gln Leu Asp 
                325                 330                 335     


Thr Glu Gly Val Gly Ser Leu Gly Pro Gly Tyr Glu Gly Arg His Ile 
            340                 345                 350         


Ala Met Glu Lys Val Ala Ser Arg Thr Tyr Arg Leu Arg Leu Glu Ala 
        355                 360                 365             


Ala Arg Pro Gly Asp Ala Gly Thr Tyr Arg Cys Leu Ala Lys Ala Tyr 
    370                 375                 380                 


Val Arg Gly Ser Gly Thr Arg Leu Arg Glu Ala Ala Ser Ala Arg Ser 
385                 390                 395                 400 


Arg Pro Leu Pro Val His Val Arg Glu Glu Gly Val Val Leu Glu Ala 
                405                 410                 415     


Val Ala Trp Leu Ala Gly Gly Thr Val Tyr Arg Gly Glu Thr Ala Ser 
            420                 425                 430         


Leu Leu Cys Asn Ile Ser Val Arg Gly Gly Pro Pro Gly Leu Arg Leu 
        435                 440                 445             


Ala Ala Ser Trp Trp Val Glu Arg Pro Glu Asp Gly Glu Leu Ser Ser 
    450                 455                 460                 


Val Pro Ala Gln Leu Val Gly Gly Val Gly Gln Asp Gly Val Ala Glu 
465                 470                 475                 480 


Leu Gly Val Arg Pro Gly Gly Gly Pro Val Ser Val Glu Leu Val Gly 
                485                 490                 495     


Pro Arg Ser His Arg Leu Arg Leu His Ser Leu Gly Pro Glu Asp Glu 
            500                 505                 510         


Gly Val Tyr His Cys Ala Pro Ser Ala Trp Val Gln His Ala Asp Tyr 
        515                 520                 525             


Ser Trp Tyr Gln Ala Gly Ser Ala Arg Ser Gly Pro Val Thr Val Tyr 
    530                 535                 540                 


Pro Tyr Met His Ala Leu Asp Thr 
545                 550         


<210>  624
<211>  698
<212>  PRT
<213>  Homo Sapiens

<400>  624

Arg Gly Lys Pro Glu Val Val Ser Val Val Gly Arg Ala Glu Glu Ser 
1               5                   10                  15      


Val Val Leu Gly Cys Asp Leu Leu Pro Pro Ala Gly Arg Pro Pro Leu 
            20                  25                  30          


His Val Ile Glu Trp Leu Arg Phe Gly Phe Leu Leu Pro Ile Phe Ile 
        35                  40                  45              


Gln Phe Gly Leu Tyr Ser Pro Arg Ile Asp Pro Asp Tyr Val Gly Arg 
    50                  55                  60                  


Val Arg Leu Gln Lys Gly Ala Ser Leu Gln Ile Glu Gly Leu Arg Val 
65                  70                  75                  80  


Glu Asp Gln Gly Trp Tyr Glu Cys Arg Val Phe Phe Leu Asp Gln His 
                85                  90                  95      


Ile Pro Glu Asp Asp Phe Ala Asn Gly Ser Trp Val His Leu Thr Val 
            100                 105                 110         


Asn Ser Pro Pro Gln Phe Gln Glu Thr Pro Pro Ala Val Leu Glu Val 
        115                 120                 125             


Gln Glu Leu Glu Pro Val Thr Leu Arg Cys Val Ala Arg Gly Ser Pro 
    130                 135                 140                 


Leu Pro His Val Thr Trp Lys Leu Arg Gly Lys Asp Leu Gly Gln Gly 
145                 150                 155                 160 


Gln Gly Gln Val Gln Val Gln Asn Gly Thr Leu Arg Ile Arg Arg Val 
                165                 170                 175     


Glu Arg Gly Ser Ser Gly Val Tyr Thr Cys Gln Ala Ser Ser Thr Glu 
            180                 185                 190         


Gly Ser Ala Thr His Ala Thr Gln Leu Leu Val Leu Gly Pro Pro Val 
        195                 200                 205             


Ile Val Val Pro Pro Lys Asn Ser Thr Val Asn Ala Ser Gln Asp Val 
    210                 215                 220                 


Ser Leu Ala Cys His Ala Glu Ala Tyr Pro Ala Asn Leu Thr Tyr Ser 
225                 230                 235                 240 


Trp Phe Gln Asp Asn Ile Asn Val Phe His Ile Ser Arg Leu Gln Pro 
                245                 250                 255     


Arg Val Gln Ile Leu Val Asp Gly Ser Leu Arg Leu Leu Ala Thr Gln 
            260                 265                 270         


Pro Asp Asp Ala Gly Cys Tyr Thr Cys Val Pro Ser Asn Gly Leu Leu 
        275                 280                 285             


His Pro Pro Ser Ala Ser Ala Tyr Leu Thr Val Leu Cys Met Pro Gly 
    290                 295                 300                 


Val Ile Arg Cys Pro Val Arg Ala Asn Pro Pro Leu Leu Phe Val Ser 
305                 310                 315                 320 


Trp Thr Lys Asp Gly Lys Ala Leu Gln Leu Asp Lys Phe Pro Gly Trp 
                325                 330                 335     


Ser Gln Gly Thr Glu Gly Ser Leu Ile Ile Ala Leu Gly Asn Glu Asp 
            340                 345                 350         


Ala Leu Gly Glu Tyr Ser Cys Thr Pro Tyr Asn Ser Leu Gly Thr Ala 
        355                 360                 365             


Gly Pro Ser Pro Val Thr Arg Val Leu Leu Lys Ala Pro Pro Ala Phe 
    370                 375                 380                 


Ile Glu Arg Pro Lys Glu Glu Tyr Phe Gln Glu Val Gly Arg Glu Leu 
385                 390                 395                 400 


Leu Ile Pro Cys Ser Ala Gln Gly Asp Pro Pro Pro Val Val Ser Trp 
                405                 410                 415     


Thr Lys Val Gly Arg Gly Leu Gln Gly Gln Ala Gln Val Asp Ser Asn 
            420                 425                 430         


Ser Ser Leu Ile Leu Arg Pro Leu Thr Lys Glu Ala His Gly His Trp 
        435                 440                 445             


Glu Cys Ser Ala Ser Asn Ala Val Ala Arg Val Ala Thr Ser Thr Asn 
    450                 455                 460                 


Val Tyr Val Leu Gly Thr Ser Pro His Val Val Thr Asn Val Ser Val 
465                 470                 475                 480 


Val Ala Leu Pro Lys Gly Ala Asn Val Ser Trp Glu Pro Gly Phe Asp 
                485                 490                 495     


Gly Gly Tyr Leu Gln Arg Phe Ser Val Trp Tyr Thr Pro Leu Ala Lys 
            500                 505                 510         


Arg Pro Asp Arg Met His His Asp Trp Val Ser Leu Ala Val Pro Val 
        515                 520                 525             


Gly Ala Ala His Leu Leu Val Pro Gly Leu Gln Pro His Thr Gln Tyr 
    530                 535                 540                 


Gln Phe Ser Val Leu Ala Gln Asn Lys Leu Gly Ser Gly Pro Phe Ser 
545                 550                 555                 560 


Glu Ile Val Leu Ser Ala Pro Glu Gly Leu Pro Thr Thr Pro Ala Ala 
                565                 570                 575     


Pro Gly Leu Pro Pro Thr Glu Ile Pro Pro Pro Leu Ser Pro Pro Arg 
            580                 585                 590         


Gly Leu Val Ala Val Arg Thr Pro Arg Gly Val Leu Leu His Trp Asp 
        595                 600                 605             


Pro Pro Glu Leu Val Pro Lys Arg Leu Asp Gly Tyr Val Leu Glu Gly 
    610                 615                 620                 


Arg Gln Gly Ser Gln Gly Trp Glu Val Leu Asp Pro Ala Val Ala Gly 
625                 630                 635                 640 


Thr Glu Thr Glu Leu Leu Val Pro Gly Leu Ile Lys Asp Val Leu Tyr 
                645                 650                 655     


Glu Phe Arg Leu Val Ala Phe Ala Gly Ser Phe Val Ser Asp Pro Ser 
            660                 665                 670         


Asn Thr Ala Asn Val Ser Thr Ser Gly Leu Glu Val Tyr Pro Ser Arg 
        675                 680                 685             


Thr Gln Leu Pro Gly Leu Leu Pro Gln Pro 
    690                 695             


<210>  625
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  625

Ser Pro Gly Gln Gly Thr Gln Ser Glu Asn Ser Cys Thr His Phe Pro 
1               5                   10                  15      


Gly Asn Leu Pro Asn Met Leu Arg Asp Leu Arg Asp Ala Phe Ser Arg 
            20                  25                  30          


Val Lys Thr Phe Phe Gln Met Lys Asp Gln Leu Asp Asn Leu Leu Leu 
        35                  40                  45              


Lys Glu Ser Leu Leu Glu Asp Phe Lys Gly Tyr Leu Gly Cys Gln Ala 
    50                  55                  60                  


Leu Ser Glu Met Ile Gln Phe Tyr Leu Glu Glu Val Met Pro Gln Ala 
65                  70                  75                  80  


Glu Asn Gln Asp Pro Asp Ile Lys Ala His Val Asn Ser Leu Gly Glu 
                85                  90                  95      


Asn Leu Lys Thr Leu Arg Leu Arg Leu Arg Arg Cys His Arg Phe Leu 
            100                 105                 110         


Pro Cys Glu Asn Lys Ser Lys Ala Val Glu Gln Val Lys Asn Ala Phe 
        115                 120                 125             


Asn Lys Leu Gln Glu Lys Gly Ile Tyr Lys Ala Met Ser Glu Phe Asp 
    130                 135                 140                 


Ile Phe Ile Asn Tyr Ile Glu Ala Tyr Met Thr Met Lys Ile Arg Asn 
145                 150                 155                 160 


<210>  626
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  626

His Gly Thr Glu Leu Pro Ser Pro Pro Ser Val Trp Phe Glu Ala Glu 
1               5                   10                  15      


Phe Phe His His Ile Leu His Trp Thr Pro Ile Pro Asn Gln Ser Glu 
            20                  25                  30          


Ser Thr Cys Tyr Glu Val Ala Leu Leu Arg Tyr Gly Ile Glu Ser Trp 
        35                  40                  45              


Asn Ser Ile Ser Asn Cys Ser Gln Thr Leu Ser Tyr Asp Leu Thr Ala 
    50                  55                  60                  


Val Thr Leu Asp Leu Tyr His Ser Asn Gly Tyr Arg Ala Arg Val Arg 
65                  70                  75                  80  


Ala Val Asp Gly Ser Arg His Ser Asn Trp Thr Val Thr Asn Thr Arg 
                85                  90                  95      


Phe Ser Val Asp Glu Val Thr Leu Thr Val Gly Ser Val Asn Leu Glu 
            100                 105                 110         


Ile His Asn Gly Phe Ile Leu Gly Lys Ile Gln Leu Pro Arg Pro Lys 
        115                 120                 125             


Met Ala Pro Ala Asn Asp Thr Tyr Glu Ser Ile Phe Ser His Phe Arg 
    130                 135                 140                 


Glu Tyr Glu Ile Ala Ile Arg Lys Val Pro Gly Asn Phe Thr Phe Thr 
145                 150                 155                 160 


His Lys Lys Val Lys His Glu Asn Phe Ser Leu Leu Thr Ser Gly Glu 
                165                 170                 175     


Val Gly Glu Phe Cys Val Gln Val Lys Pro Ser Val Ala Ser Arg Ser 
            180                 185                 190         


Asn Lys Gly Met Trp Ser Lys Glu Glu Cys Ile Ser Leu Thr Arg Gln 
        195                 200                 205             


Tyr Phe Thr Val Thr Asn 
    210                 


<210>  627
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  627

Met Val Pro Pro Pro Glu Asn Val Arg Met Asn Ser Val Asn Phe Lys 
1               5                   10                  15      


Asn Ile Leu Gln Trp Glu Ser Pro Ala Phe Ala Lys Gly Asn Leu Thr 
            20                  25                  30          


Phe Thr Ala Gln Tyr Leu Ser Tyr Arg Ile Phe Gln Asp Lys Cys Met 
        35                  40                  45              


Asn Thr Thr Leu Thr Glu Cys Asp Phe Ser Ser Leu Ser Lys Tyr Gly 
    50                  55                  60                  


Asp His Thr Leu Arg Val Arg Ala Glu Phe Ala Asp Glu His Ser Asp 
65                  70                  75                  80  


Trp Val Asn Ile Thr Phe Cys Pro Val Asp Asp Thr Ile Ile Gly Pro 
                85                  90                  95      


Pro Gly Met Gln Val Glu Val Leu Ala Asp Ser Leu His Met Arg Phe 
            100                 105                 110         


Leu Ala Pro Lys Ile Glu Asn Glu Tyr Glu Thr Trp Thr Met Lys Asn 
        115                 120                 125             


Val Tyr Asn Ser Trp Thr Tyr Asn Val Gln Tyr Trp Lys Asn Gly Thr 
    130                 135                 140                 


Asp Glu Lys Phe Gln Ile Thr Pro Gln Tyr Asp Phe Glu Val Leu Arg 
145                 150                 155                 160 


Asn Leu Glu Pro Trp Thr Thr Tyr Cys Val Gln Val Arg Gly Phe Leu 
                165                 170                 175     


Pro Asp Arg Asn Lys Ala Gly Glu Trp Ser Glu Pro Val Cys Glu Gln 
            180                 185                 190         


Thr Thr His Asp Glu Thr Val Pro Ser 
        195                 200     


<210>  628
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  628

Pro Gly Pro Pro Pro Gly Pro Pro Arg Val Ser Pro Asp Pro Arg Ala 
1               5                   10                  15      


Glu Leu Asp Ser Thr Val Leu Leu Thr Arg Ser Leu Leu Ala Asp Thr 
            20                  25                  30          


Arg Gln Leu Ala Ala Gln Leu Arg Asp Lys Phe Pro Ala Asp Gly Asp 
        35                  40                  45              


His Asn Leu Asp Ser Leu Pro Thr Leu Ala Met Ser Ala Gly Ala Leu 
    50                  55                  60                  


Gly Ala Leu Gln Leu Pro Gly Val Leu Thr Arg Leu Arg Ala Asp Leu 
65                  70                  75                  80  


Leu Ser Tyr Leu Arg His Val Gln Trp Leu Arg Arg Ala Gly Gly Ser 
                85                  90                  95      


Ser Leu Lys Thr Leu Glu Pro Glu Leu Gly Thr Leu Gln Ala Arg Leu 
            100                 105                 110         


Asp Arg Leu Leu Arg Arg Leu Gln Leu Leu Met Ser Arg Leu Ala Leu 
        115                 120                 125             


Pro Gln Pro Pro Pro Asp Pro Pro Ala Pro Pro Leu Ala Pro Pro Ser 
    130                 135                 140                 


Ser Ala Trp Gly Gly Ile Arg Ala Ala His Ala Ile Leu Gly Gly Leu 
145                 150                 155                 160 


His Leu Thr Leu Asp Trp Ala Val Arg Gly Leu Leu Leu Leu Lys Thr 
                165                 170                 175     


Arg Leu 
        


<210>  629
<211>  347
<212>  PRT
<213>  Homo Sapiens

<400>  629

Ser Pro Cys Pro Gln Ala Trp Gly Pro Pro Gly Val Gln Tyr Gly Gln 
1               5                   10                  15      


Pro Gly Arg Ser Val Lys Leu Cys Cys Pro Gly Val Thr Ala Gly Asp 
            20                  25                  30          


Pro Val Ser Trp Phe Arg Asp Gly Glu Pro Lys Leu Leu Gln Gly Pro 
        35                  40                  45              


Asp Ser Gly Leu Gly His Glu Leu Val Leu Ala Gln Ala Asp Ser Thr 
    50                  55                  60                  


Asp Glu Gly Thr Tyr Ile Cys Gln Thr Leu Asp Gly Ala Leu Gly Gly 
65                  70                  75                  80  


Thr Val Thr Leu Gln Leu Gly Tyr Pro Pro Ala Arg Pro Val Val Ser 
                85                  90                  95      


Cys Gln Ala Ala Asp Tyr Glu Asn Phe Ser Cys Thr Trp Ser Pro Ser 
            100                 105                 110         


Gln Ile Ser Gly Leu Pro Thr Arg Tyr Leu Thr Ser Tyr Arg Lys Lys 
        115                 120                 125             


Thr Val Leu Gly Ala Asp Ser Gln Arg Arg Ser Pro Ser Thr Gly Pro 
    130                 135                 140                 


Trp Pro Cys Pro Gln Asp Pro Leu Gly Ala Ala Arg Cys Val Val His 
145                 150                 155                 160 


Gly Ala Glu Phe Trp Ser Gln Tyr Arg Ile Asn Val Thr Glu Val Asn 
                165                 170                 175     


Pro Leu Gly Ala Ser Thr Arg Leu Leu Asp Val Ser Leu Gln Ser Ile 
            180                 185                 190         


Leu Arg Pro Asp Pro Pro Gln Gly Leu Arg Val Glu Ser Val Pro Gly 
        195                 200                 205             


Tyr Pro Arg Arg Leu Arg Ala Ser Trp Thr Tyr Pro Ala Ser Trp Pro 
    210                 215                 220                 


Cys Gln Pro His Phe Leu Leu Lys Phe Arg Leu Gln Tyr Arg Pro Ala 
225                 230                 235                 240 


Gln His Pro Ala Trp Ser Thr Val Glu Pro Ala Gly Leu Glu Glu Val 
                245                 250                 255     


Ile Thr Asp Ala Val Ala Gly Leu Pro His Ala Val Arg Val Ser Ala 
            260                 265                 270         


Arg Asp Phe Leu Asp Ala Gly Thr Trp Ser Thr Trp Ser Pro Glu Ala 
        275                 280                 285             


Trp Gly Thr Pro Ser Thr Gly Thr Ile Pro Lys Glu Ile Pro Ala Trp 
    290                 295                 300                 


Gly Gln Leu His Thr Gln Pro Glu Val Glu Pro Gln Val Asp Ser Pro 
305                 310                 315                 320 


Ala Pro Pro Arg Pro Ser Leu Gln Pro His Pro Arg Leu Leu Asp His 
                325                 330                 335     


Arg Asp Ser Val Glu Gln Val Ala Val Leu Ala 
            340                 345         


<210>  630
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  630

Arg Asn Leu Pro Val Ala Thr Pro Asp Pro Gly Met Phe Pro Cys Leu 
1               5                   10                  15      


His His Ser Gln Asn Leu Leu Arg Ala Val Ser Asn Met Leu Gln Lys 
            20                  25                  30          


Ala Arg Gln Thr Leu Glu Phe Tyr Pro Cys Thr Ser Glu Glu Ile Asp 
        35                  40                  45              


His Glu Asp Ile Thr Lys Asp Lys Thr Ser Thr Val Glu Ala Cys Leu 
    50                  55                  60                  


Pro Leu Glu Leu Thr Lys Asn Glu Ser Cys Leu Asn Ser Arg Glu Thr 
65                  70                  75                  80  


Ser Phe Ile Thr Asn Gly Ser Cys Leu Ala Ser Arg Lys Thr Ser Phe 
                85                  90                  95      


Met Met Ala Leu Cys Leu Ser Ser Ile Tyr Glu Asp Leu Lys Met Tyr 
            100                 105                 110         


Gln Val Glu Phe Lys Thr Met Asn Ala Lys Leu Leu Met Asp Pro Lys 
        115                 120                 125             


Arg Gln Ile Phe Leu Asp Gln Asn Met Leu Ala Val Ile Asp Glu Leu 
    130                 135                 140                 


Met Gln Ala Leu Asn Phe Asn Ser Glu Thr Val Pro Gln Lys Ser Ser 
145                 150                 155                 160 


Leu Glu Glu Pro Asp Phe Tyr Lys Thr Lys Ile Lys Leu Cys Ile Leu 
                165                 170                 175     


Leu His Ala Phe Arg Ile Arg Ala Val Thr Ile Asp Arg Val Met Ser 
            180                 185                 190         


Tyr Leu Asn Ala Ser 
        195         


<210>  631
<211>  306
<212>  PRT
<213>  Homo Sapiens

<400>  631

Ile Trp Glu Leu Lys Lys Asp Val Tyr Val Val Glu Leu Asp Trp Tyr 
1               5                   10                  15      


Pro Asp Ala Pro Gly Glu Met Val Val Leu Thr Cys Asp Thr Pro Glu 
            20                  25                  30          


Glu Asp Gly Ile Thr Trp Thr Leu Asp Gln Ser Ser Glu Val Leu Gly 
        35                  40                  45              


Ser Gly Lys Thr Leu Thr Ile Gln Val Lys Glu Phe Gly Asp Ala Gly 
    50                  55                  60                  


Gln Tyr Thr Cys His Lys Gly Gly Glu Val Leu Ser His Ser Leu Leu 
65                  70                  75                  80  


Leu Leu His Lys Lys Glu Asp Gly Ile Trp Ser Thr Asp Ile Leu Lys 
                85                  90                  95      


Asp Gln Lys Glu Pro Lys Asn Lys Thr Phe Leu Arg Cys Glu Ala Lys 
            100                 105                 110         


Asn Tyr Ser Gly Arg Phe Thr Cys Trp Trp Leu Thr Thr Ile Ser Thr 
        115                 120                 125             


Asp Leu Thr Phe Ser Val Lys Ser Ser Arg Gly Ser Ser Asp Pro Gln 
    130                 135                 140                 


Gly Val Thr Cys Gly Ala Ala Thr Leu Ser Val Glu Arg Val Arg Gly 
145                 150                 155                 160 


Asp Asn Lys Glu Tyr Glu Tyr Ser Val Glu Cys Gln Glu Asp Ser Ala 
                165                 170                 175     


Cys Pro Ala Ala Glu Glu Ser Leu Pro Ile Glu Val Met Val Asp Ala 
            180                 185                 190         


Val His Lys Leu Lys Tyr Glu Asn Tyr Thr Ser Ser Phe Phe Ile Arg 
        195                 200                 205             


Asp Ile Ile Lys Pro Asp Pro Pro Lys Asn Leu Gln Leu Lys Pro Leu 
    210                 215                 220                 


Lys Asn Ser Arg Gln Val Glu Val Ser Trp Glu Tyr Pro Asp Thr Trp 
225                 230                 235                 240 


Ser Thr Pro His Ser Tyr Phe Ser Leu Thr Phe Cys Val Gln Val Gln 
                245                 250                 255     


Gly Lys Ser Lys Arg Glu Lys Lys Asp Arg Val Phe Thr Asp Lys Thr 
            260                 265                 270         


Ser Ala Thr Val Ile Cys Arg Lys Asn Ala Ser Ile Ser Val Arg Ala 
        275                 280                 285             


Gln Asp Arg Tyr Tyr Ser Ser Ser Trp Ser Glu Trp Ala Ser Val Pro 
    290                 295                 300                 


Cys Ser 
305     


<210>  632
<211>  522
<212>  PRT
<213>  Homo Sapiens

<400>  632

Cys Arg Thr Ser Glu Cys Cys Phe Gln Asp Pro Pro Tyr Pro Asp Ala 
1               5                   10                  15      


Asp Ser Gly Ser Ala Ser Gly Pro Arg Asp Leu Arg Cys Tyr Arg Ile 
            20                  25                  30          


Ser Ser Asp Arg Tyr Glu Cys Ser Trp Gln Tyr Glu Gly Pro Thr Ala 
        35                  40                  45              


Gly Val Ser His Phe Leu Arg Cys Cys Leu Ser Ser Gly Arg Cys Cys 
    50                  55                  60                  


Tyr Phe Ala Ala Gly Ser Ala Thr Arg Leu Gln Phe Ser Asp Gln Ala 
65                  70                  75                  80  


Gly Val Ser Val Leu Tyr Thr Val Thr Leu Trp Val Glu Ser Trp Ala 
                85                  90                  95      


Arg Asn Gln Thr Glu Lys Ser Pro Glu Val Thr Leu Gln Leu Tyr Asn 
            100                 105                 110         


Ser Val Lys Tyr Glu Pro Pro Leu Gly Asp Ile Lys Val Ser Lys Leu 
        115                 120                 125             


Ala Gly Gln Leu Arg Met Glu Trp Glu Thr Pro Asp Asn Gln Val Gly 
    130                 135                 140                 


Ala Glu Val Gln Phe Arg His Arg Thr Pro Ser Ser Pro Trp Lys Leu 
145                 150                 155                 160 


Gly Asp Cys Gly Pro Gln Asp Asp Asp Thr Glu Ser Cys Leu Cys Pro 
                165                 170                 175     


Leu Glu Met Asn Val Ala Gln Glu Phe Gln Leu Arg Arg Arg Gln Leu 
            180                 185                 190         


Gly Ser Gln Gly Ser Ser Trp Ser Lys Trp Ser Ser Pro Val Cys Val 
        195                 200                 205             


Pro Pro Glu Asn Pro Pro Gln Pro Gln Val Arg Phe Ser Val Glu Gln 
    210                 215                 220                 


Leu Gly Gln Asp Gly Arg Arg Arg Leu Thr Leu Lys Glu Gln Pro Thr 
225                 230                 235                 240 


Gln Leu Glu Leu Pro Glu Gly Cys Gln Gly Leu Ala Pro Gly Thr Glu 
                245                 250                 255     


Val Thr Tyr Arg Leu Gln Leu His Met Leu Ser Cys Pro Cys Lys Ala 
            260                 265                 270         


Lys Ala Thr Gly Thr Leu His Leu Gly Lys Met Pro Tyr Leu Ser Gly 
        275                 280                 285             


Ala Ala Tyr Asn Val Ala Val Ile Ser Ser Asn Gln Phe Gly Pro Gly 
    290                 295                 300                 


Leu Asn Gln Thr Trp His Ile Pro Ala Asp Thr His Thr Glu Pro Val 
305                 310                 315                 320 


Ala Leu Asn Ile Ser Val Gly Thr Asn Gly Thr Thr Met Tyr Trp Pro 
                325                 330                 335     


Ala Arg Ala Gln Ser Met Thr Tyr Cys Ile Glu Trp Gln Pro Val Gly 
            340                 345                 350         


Gln Asp Gly Gly Leu Ala Thr Cys Ser Leu Thr Ala Pro Gln Asp Pro 
        355                 360                 365             


Asp Pro Ala Gly Met Ala Thr Tyr Ser Trp Ser Arg Gly Ser Gly Ala 
    370                 375                 380                 


Met Gly Gln Glu Lys Cys Tyr Tyr Ile Thr Ile Phe Ala Ser Ala His 
385                 390                 395                 400 


Pro Glu Lys Leu Thr Leu Trp Ser Thr Val Leu Ser Thr Tyr His Phe 
                405                 410                 415     


Gly Gly Asn Ala Ser Ala Ala Gly Thr Pro His His Val Ser Val Lys 
            420                 425                 430         


Asn His Ser Leu Asp Ser Val Ser Val Asp Trp Ala Pro Ser Leu Leu 
        435                 440                 445             


Ser Thr Cys Pro Gly Val Leu Lys Glu Tyr Val Val Arg Cys Arg Asp 
    450                 455                 460                 


Glu Asp Ser Lys Gln Val Ser Glu His Pro Val Gln Pro Thr Glu Thr 
465                 470                 475                 480 


Gln Val Thr Leu Ser Gly Leu Arg Ala Gly Val Ala Tyr Thr Val Gln 
                485                 490                 495     


Val Arg Ala Asp Thr Ala Trp Leu Arg Gly Val Trp Ser Gln Pro Gln 
            500                 505                 510         


Arg Phe Ser Ile Glu Val Gln Val Ser Asp 
        515                 520         


<210>  633
<211>  599
<212>  PRT
<213>  Homo Sapiens

<400>  633

Lys Ile Asp Ala Cys Lys Arg Gly Asp Val Thr Val Lys Pro Ser His 
1               5                   10                  15      


Val Ile Leu Leu Gly Ser Thr Val Asn Ile Thr Cys Ser Leu Lys Pro 
            20                  25                  30          


Arg Gln Gly Cys Phe His Tyr Ser Arg Arg Asn Lys Leu Ile Leu Tyr 
        35                  40                  45              


Lys Phe Asp Arg Arg Ile Asn Phe His His Gly His Ser Leu Asn Ser 
    50                  55                  60                  


Gln Val Thr Gly Leu Pro Leu Gly Thr Thr Leu Phe Val Cys Lys Leu 
65                  70                  75                  80  


Ala Cys Ile Asn Ser Asp Glu Ile Gln Ile Cys Gly Ala Glu Ile Phe 
                85                  90                  95      


Val Gly Val Ala Pro Glu Gln Pro Gln Asn Leu Ser Cys Ile Gln Lys 
            100                 105                 110         


Gly Glu Gln Gly Thr Val Ala Cys Thr Trp Glu Arg Gly Arg Asp Thr 
        115                 120                 125             


His Leu Tyr Thr Glu Tyr Thr Leu Gln Leu Ser Gly Pro Lys Asn Leu 
    130                 135                 140                 


Thr Trp Gln Lys Gln Cys Lys Asp Ile Tyr Cys Asp Tyr Leu Asp Phe 
145                 150                 155                 160 


Gly Ile Asn Leu Thr Pro Glu Ser Pro Glu Ser Asn Phe Thr Ala Lys 
                165                 170                 175     


Val Thr Ala Val Asn Ser Leu Gly Ser Ser Ser Ser Leu Pro Ser Thr 
            180                 185                 190         


Phe Thr Phe Leu Asp Ile Val Arg Pro Leu Pro Pro Trp Asp Ile Arg 
        195                 200                 205             


Ile Lys Phe Gln Lys Ala Ser Val Ser Arg Cys Thr Leu Tyr Trp Arg 
    210                 215                 220                 


Asp Glu Gly Leu Val Leu Leu Asn Arg Leu Arg Tyr Arg Pro Ser Asn 
225                 230                 235                 240 


Ser Arg Leu Trp Asn Met Val Asn Val Thr Lys Ala Lys Gly Arg His 
                245                 250                 255     


Asp Leu Leu Asp Leu Lys Pro Phe Thr Glu Tyr Glu Phe Gln Ile Ser 
            260                 265                 270         


Ser Lys Leu His Leu Tyr Lys Gly Ser Trp Ser Asp Trp Ser Glu Ser 
        275                 280                 285             


Leu Arg Ala Gln Thr Pro Glu Glu Glu Pro Thr Gly Met Leu Asp Val 
    290                 295                 300                 


Trp Tyr Met Lys Arg His Ile Asp Tyr Ser Arg Gln Gln Ile Ser Leu 
305                 310                 315                 320 


Phe Trp Lys Asn Leu Ser Val Ser Glu Ala Arg Gly Lys Ile Leu His 
                325                 330                 335     


Tyr Gln Val Thr Leu Gln Glu Leu Thr Gly Gly Lys Ala Met Thr Gln 
            340                 345                 350         


Asn Ile Thr Gly His Thr Ser Trp Thr Thr Val Ile Pro Arg Thr Gly 
        355                 360                 365             


Asn Trp Ala Val Ala Val Ser Ala Ala Asn Ser Lys Gly Ser Ser Leu 
    370                 375                 380                 


Pro Thr Arg Ile Asn Ile Met Asn Leu Cys Glu Ala Gly Leu Leu Ala 
385                 390                 395                 400 


Pro Arg His Val Ser Ala Asn Ser Glu Gly Met Asp Asn Ile Leu Val 
                405                 410                 415     


Thr Trp Gln Pro Pro Arg Lys Asp Pro Ser Ala Val Gln Glu Tyr Val 
            420                 425                 430         


Val Glu Trp Arg Glu Leu His Pro Gly Gly Asp Thr Gln Val Pro Leu 
        435                 440                 445             


Asn Trp Leu Arg Ser Arg Pro Tyr Asn Val Ser Ala Leu Ile Ser Glu 
    450                 455                 460                 


Asn Ile Lys Ser Tyr Ile Cys Tyr Glu Ile Arg Val Tyr Ala Leu Ser 
465                 470                 475                 480 


Gly Asp Gln Gly Gly Cys Ser Ser Ile Leu Gly Asn Ser Lys His Lys 
                485                 490                 495     


Ala Pro Leu Ser Gly Pro His Ile Asn Ala Ile Thr Glu Glu Lys Gly 
            500                 505                 510         


Ser Ile Leu Ile Ser Trp Asn Ser Ile Pro Val Gln Glu Gln Met Gly 
        515                 520                 525             


Cys Leu Leu His Tyr Arg Ile Tyr Trp Lys Glu Arg Asp Ser Asn Ser 
    530                 535                 540                 


Gln Pro Gln Leu Cys Glu Ile Pro Tyr Arg Val Ser Gln Asn Ser His 
545                 550                 555                 560 


Pro Ile Asn Ser Leu Gln Pro Arg Val Thr Tyr Val Leu Trp Met Thr 
                565                 570                 575     


Ala Leu Thr Ala Ala Gly Glu Ser Ser His Gly Asn Glu Arg Glu Phe 
            580                 585                 590         


Cys Leu Gln Gly Lys Ala Asn 
        595                 


<210>  634
<211>  122
<212>  PRT
<213>  Homo Sapiens

<400>  634

Leu Thr Cys Leu Gly Gly Phe Ala Ser Pro Gly Pro Val Pro Pro Ser 
1               5                   10                  15      


Thr Ala Leu Arg Glu Leu Ile Glu Glu Leu Val Asn Ile Thr Gln Asn 
            20                  25                  30          


Gln Lys Ala Pro Leu Cys Asn Gly Ser Met Val Trp Ser Ile Asn Leu 
        35                  40                  45              


Thr Ala Gly Met Tyr Cys Ala Ala Leu Glu Ser Leu Ile Asn Val Ser 
    50                  55                  60                  


Gly Cys Ser Ala Ile Glu Lys Thr Gln Arg Met Leu Ser Gly Phe Cys 
65                  70                  75                  80  


Pro His Lys Val Ser Ala Gly Gln Phe Ser Ser Leu His Val Arg Asp 
                85                  90                  95      


Thr Lys Ile Glu Val Ala Gln Phe Val Lys Asp Leu Leu Leu His Leu 
            100                 105                 110         


Lys Lys Leu Phe Arg Glu Gly Gln Phe Asn 
        115                 120         


<210>  635
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  635

Gly Gly Gly Gly Ala Ala Pro Thr Glu Thr Gln Pro Pro Val Thr Asn 
1               5                   10                  15      


Leu Ser Val Ser Val Glu Asn Leu Cys Thr Val Ile Trp Thr Trp Asn 
            20                  25                  30          


Pro Pro Glu Gly Ala Ser Ser Asn Cys Ser Leu Trp Tyr Phe Ser His 
        35                  40                  45              


Phe Gly Asp Lys Gln Asp Lys Lys Ile Ala Pro Glu Thr Arg Arg Ser 
    50                  55                  60                  


Ile Glu Val Pro Leu Asn Glu Arg Ile Cys Leu Gln Val Gly Ser Gln 
65                  70                  75                  80  


Cys Ser Thr Asn Glu Ser Glu Lys Pro Ser Ile Leu Val Glu Lys Cys 
                85                  90                  95      


Ile Ser Pro Pro Glu Gly Asp Pro Glu Ser Ala Val Thr Glu Leu Gln 
            100                 105                 110         


Cys Ile Trp His Asn Leu Ser Tyr Met Lys Cys Ser Trp Leu Pro Gly 
        115                 120                 125             


Arg Asn Thr Ser Pro Asp Thr Asn Tyr Thr Leu Tyr Tyr Trp His Arg 
    130                 135                 140                 


Ser Leu Glu Lys Ile His Gln Cys Glu Asn Ile Phe Arg Glu Gly Gln 
145                 150                 155                 160 


Tyr Phe Gly Cys Ser Phe Asp Leu Thr Lys Val Lys Asp Ser Ser Phe 
                165                 170                 175     


Glu Gln His Ser Val Gln Ile Met Val Lys Asp Asn Ala Gly Lys Ile 
            180                 185                 190         


Lys Pro Ser Phe Asn Ile Val Pro Leu Thr Ser Arg Val Lys Pro Asp 
        195                 200                 205             


Pro Pro His Ile Lys Asn Leu Ser Phe His Asn Asp Asp Leu Tyr Val 
    210                 215                 220                 


Gln Trp Glu Asn Pro Gln Asn Phe Ile Ser Arg Cys Leu Phe Tyr Glu 
225                 230                 235                 240 


Val Glu Val Asn Asn Ser Gln Thr Glu Thr His Asn Val Phe Tyr Val 
                245                 250                 255     


Gln Glu Ala Lys Cys Glu Asn Pro Glu Phe Glu Arg Asn Val Glu Asn 
            260                 265                 270         


Thr Ser Cys Phe Met Val Pro Gly Val Leu Pro Asp Thr Leu Asn Thr 
        275                 280                 285             


Val Arg Ile Arg Val Lys Thr Asn Lys Leu Cys Tyr Glu Asp Asp Lys 
    290                 295                 300                 


Leu Trp Ser Asn Trp Ser Gln Glu Met Ser Ile Gly Lys Lys Arg Asn 
305                 310                 315                 320 


Ser Thr 
        


<210>  636
<211>  317
<212>  PRT
<213>  Homo Sapiens

<400>  636

Asp Thr Glu Ile Lys Val Asn Pro Pro Gln Asp Phe Glu Ile Val Asp 
1               5                   10                  15      


Pro Gly Tyr Leu Gly Tyr Leu Tyr Leu Gln Trp Gln Pro Pro Leu Ser 
            20                  25                  30          


Leu Asp His Phe Lys Glu Cys Thr Val Glu Tyr Glu Leu Lys Tyr Arg 
        35                  40                  45              


Asn Ile Gly Ser Glu Thr Trp Lys Thr Ile Ile Thr Lys Asn Leu His 
    50                  55                  60                  


Tyr Lys Asp Gly Phe Asp Leu Asn Lys Gly Ile Glu Ala Lys Ile His 
65                  70                  75                  80  


Thr Leu Leu Pro Trp Gln Cys Thr Asn Gly Ser Glu Val Gln Ser Ser 
                85                  90                  95      


Trp Ala Glu Thr Thr Tyr Trp Ile Ser Pro Gln Gly Ile Pro Glu Thr 
            100                 105                 110         


Lys Val Gln Asp Met Asp Cys Val Tyr Tyr Asn Trp Gln Tyr Leu Leu 
        115                 120                 125             


Cys Ser Trp Lys Pro Gly Ile Gly Val Leu Leu Asp Thr Asn Tyr Asn 
    130                 135                 140                 


Leu Phe Tyr Trp Tyr Glu Gly Leu Asp His Ala Leu Gln Cys Val Asp 
145                 150                 155                 160 


Tyr Ile Lys Ala Asp Gly Gln Asn Ile Gly Cys Arg Phe Pro Tyr Leu 
                165                 170                 175     


Glu Ala Ser Asp Tyr Lys Asp Phe Tyr Ile Cys Val Asn Gly Ser Ser 
            180                 185                 190         


Glu Asn Lys Pro Ile Arg Ser Ser Tyr Phe Thr Phe Gln Leu Gln Asn 
        195                 200                 205             


Ile Val Lys Pro Leu Pro Pro Val Tyr Leu Thr Phe Thr Arg Glu Ser 
    210                 215                 220                 


Ser Cys Glu Ile Lys Leu Lys Trp Ser Ile Pro Leu Gly Pro Ile Pro 
225                 230                 235                 240 


Ala Arg Cys Phe Asp Tyr Glu Ile Glu Ile Arg Glu Asp Asp Thr Thr 
                245                 250                 255     


Leu Val Thr Ala Thr Val Glu Asn Glu Thr Tyr Thr Leu Lys Thr Thr 
            260                 265                 270         


Asn Glu Thr Arg Gln Leu Cys Phe Val Val Arg Ser Lys Val Asn Ile 
        275                 280                 285             


Tyr Cys Ser Asp Asp Gly Ile Trp Ser Glu Trp Ser Asp Lys Gln Cys 
    290                 295                 300                 


Trp Glu Gly Glu Asp Leu Ser Lys Lys Thr Leu Leu Arg 
305                 310                 315         


<210>  637
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  637

Asn Trp Val Asn Val Ile Ser Asp Leu Lys Lys Ile Glu Asp Leu Ile 
1               5                   10                  15      


Gln Ser Met His Ile Asp Ala Thr Leu Tyr Thr Glu Ser Asp Val His 
            20                  25                  30          


Pro Ser Cys Lys Val Thr Ala Met Lys Cys Phe Leu Leu Glu Leu Gln 
        35                  40                  45              


Val Ile Ser Leu Glu Ser Gly Asp Ala Ser Ile His Asp Thr Val Glu 
    50                  55                  60                  


Asn Leu Ile Ile Leu Ala Asn Asn Ser Leu Ser Ser Asn Gly Asn Val 
65                  70                  75                  80  


Thr Glu Ser Gly Cys Lys Glu Cys Glu Glu Leu Glu Glu Lys Asn Ile 
                85                  90                  95      


Lys Glu Phe Leu Gln Ser Phe Val His Ile Val Gln Met Phe Ile Asn 
            100                 105                 110         


Thr Ser 
        


<210>  638
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  638

Ile Thr Cys Pro Pro Pro Met Ser Val Glu His Ala Asp Ile Trp Val 
1               5                   10                  15      


Lys Ser Tyr Ser Leu Tyr Ser Arg Glu Arg Tyr Ile Cys Asn Ser Gly 
            20                  25                  30          


Phe Lys Arg Lys Ala Gly Thr Ser Ser Leu Thr Glu Cys Val Leu Asn 
        35                  40                  45              


Lys Ala Thr Asn Val Ala His Trp Thr Thr Pro Ser Leu Lys Cys Ile 
    50                  55                  60                  


Arg Asp Pro Ala Leu Val His Gln Arg Pro Ala Pro Pro Ser Thr Val 
65                  70                  75                  80  


Thr Thr Ala Gly Val Thr Pro Gln Pro Glu Ser Leu Ser Pro Ser Gly 
                85                  90                  95      


Lys Glu Pro Ala Ala Ser Ser Pro Ser Ser Asn Asn Thr Ala Ala Thr 
            100                 105                 110         


Thr Ala Ala Ile Val Pro Gly Ser Gln Leu Met Pro Ser Lys Ser Pro 
        115                 120                 125             


Ser Thr Gly Thr Thr Glu Ile Ser Ser His Glu Ser Ser His Gly Thr 
    130                 135                 140                 


Pro Ser Gln Thr Thr Ala Lys Thr Trp Glu Leu Thr Ala Ser Ala Ser 
145                 150                 155                 160 


His Gln Pro Pro Gly Val Tyr Pro Gln Gly His Ser Asp Thr Thr 
                165                 170                 175 


<210>  639
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  639

Ser Ala Ala Ser Ala Ser Ala Ala Ser Asp Val Ser Val Glu Ser Thr 
1               5                   10                  15      


Glu Ala Thr Val Cys Thr Val Thr Leu Glu Lys Met Ser Ala Gly Leu 
            20                  25                  30          


Gly Phe Ser Leu Glu Gly Gly Lys Gly Ser Leu His Gly Asp Lys Pro 
        35                  40                  45              


Leu Thr Ile Asn Arg Ile Phe Lys Gly Ala Ala Ser Glu Gln Ser Glu 
    50                  55                  60                  


Thr Val Gln Pro Gly Asp Glu Ile Leu Gln Leu Gly Gly Thr Ala Met 
65                  70                  75                  80  


Gln Gly Leu Thr Arg Phe Glu Ala Trp Asn Ile Ile Lys Ala Leu Pro 
                85                  90                  95      


Asp Gly Pro Val Thr Ile Val Ile Arg Arg Lys Ser Leu Gln Ser Lys 
            100                 105                 110         


Glu Thr Thr Ala Ala Gly Asp Ser 
        115                 120 


<210>  640
<211>  132
<212>  PRT
<213>  Homo Sapiens

<400>  640

Gly Ile Thr Ile Pro Arg Asn Pro Gly Cys Pro Asn Ser Glu Asp Lys 
1               5                   10                  15      


Asn Phe Pro Arg Thr Val Met Val Asn Leu Asn Ile His Asn Arg Asn 
            20                  25                  30          


Thr Asn Thr Asn Pro Lys Arg Ser Ser Asp Tyr Tyr Asn Arg Ser Thr 
        35                  40                  45              


Ser Pro Trp Asn Leu His Arg Asn Glu Asp Pro Glu Arg Tyr Pro Ser 
    50                  55                  60                  


Val Ile Trp Glu Ala Lys Cys Arg His Leu Gly Cys Ile Asn Ala Asp 
65                  70                  75                  80  


Gly Asn Val Asp Tyr His Met Asn Ser Val Pro Ile Gln Gln Glu Ile 
                85                  90                  95      


Leu Val Leu Arg Arg Glu Pro Pro His Cys Pro Asn Ser Phe Arg Leu 
            100                 105                 110         


Glu Lys Ile Leu Val Ser Val Gly Cys Thr Cys Val Thr Pro Ile Val 
        115                 120                 125             


His His Val Ala 
    130         


<210>  641
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  641

Gln Pro Arg Ser Pro Lys Ser Lys Arg Lys Gly Gln Gly Arg Pro Gly 
1               5                   10                  15      


Pro Leu Ala Pro Gly Pro His Gln Val Pro Leu Asp Leu Val Ser Arg 
            20                  25                  30          


Met Lys Pro Tyr Ala Arg Met Glu Glu Tyr Glu Arg Asn Ile Glu Glu 
        35                  40                  45              


Met Val Ala Gln Leu Arg Asn Ser Ser Glu Leu Ala Gln Arg Lys Cys 
    50                  55                  60                  


Glu Val Asn Leu Gln Leu Trp Met Ser Asn Lys Arg Ser Leu Ser Pro 
65                  70                  75                  80  


Trp Gly Tyr Ser Ile Asn His Asp Pro Ser Arg Ile Pro Val Asp Leu 
                85                  90                  95      


Pro Glu Ala Arg Cys Leu Cys Leu Gly Cys Val Asn Pro Phe Thr Met 
            100                 105                 110         


Gln Glu Asp Arg Ser Met Val Ser Val Pro Val Phe Ser Gln Val Pro 
        115                 120                 125             


Val Arg Arg Arg Leu Cys Pro Pro Pro Pro Arg Thr Gly Pro Cys Arg 
    130                 135                 140                 


Gln Arg Ala Val Met Glu Thr Ile Ala Val Gly Cys Thr Cys Ile Phe 
145                 150                 155                 160 


<210>  642
<211>  275
<212>  PRT
<213>  Homo Sapiens

<400>  642

Arg Glu Pro Thr Val Gln Cys Gly Ser Glu Thr Gly Pro Ser Pro Glu 
1               5                   10                  15      


Trp Met Leu Gln His Asp Leu Ile Pro Gly Asp Leu Arg Asp Leu Arg 
            20                  25                  30          


Val Glu Pro Val Thr Thr Ser Val Ala Thr Gly Asp Tyr Ser Ile Leu 
        35                  40                  45              


Met Asn Val Ser Trp Val Leu Arg Ala Asp Ala Ser Ile Arg Leu Leu 
    50                  55                  60                  


Lys Ala Thr Lys Ile Cys Val Thr Gly Lys Ser Asn Phe Gln Ser Tyr 
65                  70                  75                  80  


Ser Cys Val Arg Cys Asn Tyr Thr Glu Ala Phe Gln Thr Gln Thr Arg 
                85                  90                  95      


Pro Ser Gly Gly Lys Trp Thr Phe Ser Tyr Ile Gly Phe Pro Val Glu 
            100                 105                 110         


Leu Asn Thr Val Tyr Phe Ile Gly Ala His Asn Ile Pro Asn Ala Asn 
        115                 120                 125             


Met Asn Glu Asp Gly Pro Ser Met Ser Val Asn Phe Thr Ser Pro Gly 
    130                 135                 140                 


Cys Leu Asp His Ile Met Lys Tyr Lys Lys Lys Cys Val Lys Ala Gly 
145                 150                 155                 160 


Ser Leu Trp Asp Pro Asn Ile Thr Ala Cys Lys Lys Asn Glu Glu Thr 
                165                 170                 175     


Val Glu Val Asn Phe Thr Thr Thr Pro Leu Gly Asn Arg Tyr Met Ala 
            180                 185                 190         


Leu Ile Gln His Ser Thr Ile Ile Gly Phe Ser Gln Val Phe Glu Pro 
        195                 200                 205             


His Gln Lys Lys Gln Thr Arg Ala Ser Val Val Ile Pro Val Thr Gly 
    210                 215                 220                 


Asp Ser Glu Gly Ala Thr Val Gln Leu Thr Pro Tyr Phe Pro Thr Cys 
225                 230                 235                 240 


Gly Ser Asp Cys Ile Arg His Lys Gly Thr Val Val Leu Cys Pro Gln 
                245                 250                 255     


Thr Gly Val Pro Phe Pro Leu Asp Asn Asn Lys Ser Lys Pro Gly Gly 
            260                 265                 270         


Trp Leu Pro 
        275 


<210>  643
<211>  179
<212>  PRT
<213>  Homo Sapiens

<400>  643

His His Asp Pro Ser Leu Arg Gly His Pro His Ser His Gly Thr Pro 
1               5                   10                  15      


His Cys Tyr Ser Ala Glu Glu Leu Pro Leu Gly Gln Ala Pro Pro His 
            20                  25                  30          


Leu Leu Ala Arg Gly Ala Lys Trp Gly Gln Ala Leu Pro Val Ala Leu 
        35                  40                  45              


Val Ser Ser Leu Glu Ala Ala Ser His Arg Gly Arg His Glu Arg Pro 
    50                  55                  60                  


Ser Ala Thr Thr Gln Cys Pro Val Leu Arg Pro Glu Glu Val Leu Glu 
65                  70                  75                  80  


Ala Asp Thr His Gln Arg Ser Ile Ser Pro Trp Arg Tyr Arg Val Asp 
                85                  90                  95      


Thr Asp Glu Asp Arg Tyr Pro Gln Lys Leu Ala Phe Ala Glu Cys Leu 
            100                 105                 110         


Cys Arg Gly Cys Ile Asp Ala Arg Thr Gly Arg Glu Thr Ala Ala Leu 
        115                 120                 125             


Asn Ser Val Arg Leu Leu Gln Ser Leu Leu Val Leu Arg Arg Arg Pro 
    130                 135                 140                 


Cys Ser Arg Asp Gly Ser Gly Leu Pro Thr Pro Gly Ala Phe Ala Phe 
145                 150                 155                 160 


His Thr Glu Phe Ile His Val Pro Val Gly Cys Thr Cys Val Leu Pro 
                165                 170                 175     


Arg Ser Val 
            


<210>  644
<211>  187
<212>  PRT
<213>  Homo Sapiens

<400>  644

Ala Gly Ala Pro Arg Ala Gly Arg Arg Pro Ala Arg Pro Arg Gly Cys 
1               5                   10                  15      


Ala Asp Arg Pro Glu Glu Leu Leu Glu Gln Leu Tyr Gly Arg Leu Ala 
            20                  25                  30          


Ala Gly Val Leu Ser Ala Phe His His Thr Leu Gln Leu Gly Pro Arg 
        35                  40                  45              


Glu Gln Ala Arg Asn Ala Ser Cys Pro Ala Gly Gly Arg Pro Ala Asp 
    50                  55                  60                  


Arg Arg Phe Arg Pro Pro Thr Asn Leu Arg Ser Val Ser Pro Trp Ala 
65                  70                  75                  80  


Tyr Arg Ile Ser Tyr Asp Pro Ala Arg Tyr Pro Arg Tyr Leu Pro Glu 
                85                  90                  95      


Ala Tyr Cys Leu Cys Arg Gly Cys Leu Thr Gly Leu Phe Gly Glu Glu 
            100                 105                 110         


Asp Val Arg Phe Arg Ser Ala Pro Val Tyr Met Pro Thr Val Val Leu 
        115                 120                 125             


Arg Arg Thr Pro Ala Cys Ala Gly Gly Arg Ser Val Tyr Thr Glu Ala 
    130                 135                 140                 


Tyr Val Thr Ile Pro Val Gly Cys Thr Cys Val Pro Glu Pro Glu Lys 
145                 150                 155                 160 


Asp Ala Asp Ser Ile Asn Ser Ser Ile Asp Lys Gln Gly Ala Lys Leu 
                165                 170                 175     


Leu Leu Gly Pro Asn Asp Ala Pro Ala Gly Pro 
            180                 185         


<210>  645
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  645

Arg Lys Ile Pro Lys Val Gly His Thr Phe Phe Gln Lys Pro Glu Ser 
1               5                   10                  15      


Cys Pro Pro Val Pro Gly Gly Ser Met Lys Leu Asp Ile Gly Ile Ile 
            20                  25                  30          


Asn Glu Asn Gln Arg Val Ser Met Ser Arg Asn Ile Glu Ser Arg Ser 
        35                  40                  45              


Thr Ser Pro Trp Asn Tyr Thr Val Thr Trp Asp Pro Asn Arg Tyr Pro 
    50                  55                  60                  


Ser Glu Val Val Gln Ala Gln Cys Arg Asn Leu Gly Cys Ile Asn Ala 
65                  70                  75                  80  


Gln Gly Lys Glu Asp Ile Ser Met Asn Ser Val Pro Ile Gln Gln Glu 
                85                  90                  95      


Thr Leu Val Val Arg Arg Lys His Gln Gly Cys Ser Val Ser Phe Gln 
            100                 105                 110         


Leu Glu Lys Val Leu Val Thr Val Gly Cys Thr Cys Val Thr Pro Val 
        115                 120                 125             


Ile His Arg Val Gln 
    130             


<210>  646
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  646

Leu Arg Leu Leu Asp His Arg Ala Leu Val Cys Ser Gln Pro Gly Leu 
1               5                   10                  15      


Asn Cys Thr Val Lys Asn Ser Thr Cys Leu Asp Asp Ser Trp Ile His 
            20                  25                  30          


Pro Arg Asn Leu Thr Pro Ser Ser Pro Lys Asp Leu Gln Ile Gln Leu 
        35                  40                  45              


His Phe Ala His Thr Gln Gln Gly Asp Leu Phe Pro Val Ala His Ile 
    50                  55                  60                  


Glu Trp Thr Leu Gln Thr Asp Ala Ser Ile Leu Tyr Leu Glu Gly Ala 
65                  70                  75                  80  


Glu Leu Ser Val Leu Gln Leu Asn Thr Asn Glu Arg Leu Cys Val Arg 
                85                  90                  95      


Phe Glu Phe Leu Ser Lys Leu Arg His His His Arg Arg Trp Arg Phe 
            100                 105                 110         


Thr Phe Ser His Phe Val Val Asp Pro Asp Gln Glu Tyr Glu Val Thr 
        115                 120                 125             


Val His His Leu Pro Lys Pro Ile Pro Asp Gly Asp Pro Asn His Gln 
    130                 135                 140                 


Ser Lys Asn Phe Leu Val Pro Asp Cys Glu His Ala Arg Met Lys Val 
145                 150                 155                 160 


Thr Thr Pro Cys Met Ser Ser Gly Ser Leu Trp Asp Pro Asn Ile Thr 
                165                 170                 175     


Val Glu Thr Leu Glu Ala His Gln Leu Arg Val Ser Phe Thr Leu Trp 
            180                 185                 190         


Asn Glu Ser Thr His Tyr Gln Ile Leu Leu Thr Ser Phe Pro His Met 
        195                 200                 205             


Glu Asn His Ser Cys Phe Glu His Met His His Ile Pro Ala Pro Arg 
    210                 215                 220                 


Pro Glu Glu Phe His Gln Arg Ser Asn Val Thr Leu Thr Leu Arg Asn 
225                 230                 235                 240 


Leu Lys Gly Cys Cys Arg His Gln Val Gln Ile Gln Pro Phe Phe Ser 
                245                 250                 255     


Ser Cys Leu Asn Asp Cys Leu Arg His Ser Ala Thr Val Ser Cys Pro 
            260                 265                 270         


Glu Met Pro Asp Thr Pro Glu Pro Ile Pro Asp Tyr Met Pro Leu Trp 
        275                 280                 285             


<210>  647
<211>  432
<212>  PRT
<213>  Homo Sapiens

<400>  647

Leu Glu Arg Leu Val Gly Pro Gln Asp Ala Thr His Cys Ser Pro Gly 
1               5                   10                  15      


Leu Ser Cys Arg Leu Trp Asp Ser Asp Ile Leu Cys Leu Pro Gly Asp 
            20                  25                  30          


Ile Val Pro Ala Pro Gly Pro Val Leu Ala Pro Thr His Leu Gln Thr 
        35                  40                  45              


Glu Leu Val Leu Arg Cys Gln Lys Glu Thr Asp Cys Asp Leu Cys Leu 
    50                  55                  60                  


Arg Val Ala Val His Leu Ala Val His Gly His Trp Glu Glu Pro Glu 
65                  70                  75                  80  


Asp Glu Glu Lys Phe Gly Gly Ala Ala Asp Ser Gly Val Glu Glu Pro 
                85                  90                  95      


Arg Asn Ala Ser Leu Gln Ala Gln Val Val Leu Ser Phe Gln Ala Tyr 
            100                 105                 110         


Pro Thr Ala Arg Cys Val Leu Leu Glu Val Gln Val Pro Ala Ala Leu 
        115                 120                 125             


Val Gln Phe Gly Gln Ser Val Gly Ser Val Val Tyr Asp Cys Phe Glu 
    130                 135                 140                 


Ala Ala Leu Gly Ser Glu Val Arg Ile Trp Ser Tyr Thr Gln Pro Arg 
145                 150                 155                 160 


Tyr Glu Lys Glu Leu Asn His Thr Gln Gln Leu Pro Ala Leu Pro Trp 
                165                 170                 175     


Leu Asn Val Ser Ala Asp Gly Asp Asn Val His Leu Val Leu Asn Val 
            180                 185                 190         


Ser Glu Glu Gln His Phe Gly Leu Ser Leu Tyr Trp Asn Gln Val Gln 
        195                 200                 205             


Gly Pro Pro Lys Pro Arg Trp His Lys Asn Leu Thr Gly Pro Gln Ile 
    210                 215                 220                 


Ile Thr Leu Asn His Thr Asp Leu Val Pro Cys Leu Cys Ile Gln Val 
225                 230                 235                 240 


Trp Pro Leu Glu Pro Asp Ser Val Arg Thr Asn Ile Cys Pro Phe Arg 
                245                 250                 255     


Glu Asp Pro Arg Ala His Gln Asn Leu Trp Gln Ala Ala Arg Leu Arg 
            260                 265                 270         


Leu Leu Thr Leu Gln Ser Trp Leu Leu Asp Ala Pro Cys Ser Leu Pro 
        275                 280                 285             


Ala Glu Ala Ala Leu Cys Trp Arg Ala Pro Gly Gly Asp Pro Cys Gln 
    290                 295                 300                 


Pro Leu Val Pro Pro Leu Ser Trp Glu Asn Val Thr Val Asp Lys Val 
305                 310                 315                 320 


Leu Glu Phe Pro Leu Leu Lys Gly His Pro Asn Leu Cys Val Gln Val 
                325                 330                 335     


Asn Ser Ser Glu Lys Leu Gln Leu Gln Glu Cys Leu Trp Ala Asp Ser 
            340                 345                 350         


Leu Gly Pro Leu Lys Asp Asp Val Leu Leu Leu Glu Thr Arg Gly Pro 
        355                 360                 365             


Gln Asp Asn Arg Ser Leu Cys Ala Leu Glu Pro Ser Gly Cys Thr Ser 
    370                 375                 380                 


Leu Pro Ser Lys Ala Ser Thr Arg Ala Ala Arg Leu Gly Glu Tyr Leu 
385                 390                 395                 400 


Leu Gln Asp Leu Gln Ser Gly Gln Cys Leu Gln Leu Trp Asp Asp Asp 
                405                 410                 415     


Leu Gly Ala Leu Trp Ala Cys Pro Met Asp Lys Tyr Ile His Lys Arg 
            420                 425                 430         


<210>  648
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  648

Met Glu Ser Gln Pro Phe Leu Asn Met Lys Phe Glu Thr Asp Tyr Phe 
1               5                   10                  15      


Val Lys Val Val Pro Phe Pro Ser Ile Lys Asn Glu Ser Asn Tyr His 
            20                  25                  30          


Pro Phe Phe Phe Arg Thr Arg Ala Cys Asp Leu Leu Leu Gln Pro Asp 
        35                  40                  45              


Asn Leu Ala Cys Lys Pro Phe Trp Lys Pro Arg Asn Leu Asn Ile Ser 
    50                  55                  60                  


Gln His Gly Ser Asp Met Gln Val Ser Phe Asp His Ala Pro His Asn 
65                  70                  75                  80  


Phe Gly Phe Arg Phe Phe Tyr Leu His Tyr Lys Leu Lys His Glu Gly 
                85                  90                  95      


Pro Phe Lys Arg Lys Thr Cys Lys Gln Glu Gln Thr Thr Glu Thr Thr 
            100                 105                 110         


Ser Cys Leu Leu Gln Asn Val Ser Pro Gly Asp Tyr Ile Ile Glu Leu 
        115                 120                 125             


Val Asp Asp Thr Asn Thr Thr Arg Lys Val Met His Tyr Ala Leu Lys 
    130                 135                 140                 


Pro Val His Ser Pro Trp Ala Gly Pro Ile Arg 
145                 150                 155 


<210>  649
<211>  431
<212>  PRT
<213>  Homo Sapiens

<400>  649

Ala Gly Ile Gly Phe Arg His Leu Pro His Trp Asn Thr Arg Cys Pro 
1               5                   10                  15      


Leu Ala Ser His Thr Asp Asp Ser Phe Thr Gly Ser Ser Ala Tyr Ile 
            20                  25                  30          


Pro Cys Arg Thr Trp Trp Ala Leu Phe Ser Thr Lys Pro Trp Cys Val 
        35                  40                  45              


Arg Val Trp His Cys Ser Arg Cys Leu Cys Gln His Leu Leu Ser Gly 
    50                  55                  60                  


Gly Ser Gly Leu Gln Arg Gly Leu Phe His Leu Leu Val Gln Lys Ser 
65                  70                  75                  80  


Lys Lys Ser Ser Thr Phe Lys Phe Tyr Arg Arg His Lys Met Pro Ala 
                85                  90                  95      


Pro Ala Gln Arg Lys Leu Leu Pro Arg Arg His Leu Ser Glu Lys Ser 
            100                 105                 110         


His His Ile Ser Ile Pro Ser Pro Asp Ile Ser His Lys Gly Leu Arg 
        115                 120                 125             


Ser Lys Arg Thr Gln Pro Ser Asp Pro Glu Thr Trp Glu Ser Leu Pro 
    130                 135                 140                 


Arg Leu Asp Ser Gln Arg His Gly Gly Pro Glu Phe Ser Phe Asp Leu 
145                 150                 155                 160 


Leu Pro Glu Ala Arg Ala Ile Arg Val Thr Ile Ser Ser Gly Pro Glu 
                165                 170                 175     


Val Ser Val Arg Leu Cys His Gln Trp Ala Leu Glu Cys Glu Glu Leu 
            180                 185                 190         


Ser Ser Pro Tyr Asp Val Gln Lys Ile Val Ser Gly Gly His Thr Val 
        195                 200                 205             


Glu Leu Pro Tyr Glu Phe Leu Leu Pro Cys Leu Cys Ile Glu Ala Ser 
    210                 215                 220                 


Tyr Leu Gln Glu Asp Thr Val Arg Arg Lys Lys Cys Pro Phe Gln Ser 
225                 230                 235                 240 


Trp Pro Glu Ala Tyr Gly Ser Asp Phe Trp Lys Ser Val His Phe Thr 
                245                 250                 255     


Asp Tyr Ser Gln His Thr Gln Met Val Met Ala Leu Thr Leu Arg Cys 
            260                 265                 270         


Pro Leu Lys Leu Glu Ala Ala Leu Cys Gln Arg His Asp Trp His Thr 
        275                 280                 285             


Leu Cys Lys Asp Leu Pro Asn Ala Thr Ala Arg Glu Ser Asp Gly Trp 
    290                 295                 300                 


Tyr Val Leu Glu Lys Val Asp Leu His Pro Gln Leu Cys Phe Lys Phe 
305                 310                 315                 320 


Ser Phe Gly Asn Ser Ser His Val Glu Cys Pro His Gln Thr Gly Ser 
                325                 330                 335     


Leu Thr Ser Trp Asn Val Ser Met Asp Thr Gln Ala Gln Gln Leu Ile 
            340                 345                 350         


Leu His Phe Ser Ser Arg Met His Ala Thr Phe Ser Ala Ala Trp Ser 
        355                 360                 365             


Leu Pro Gly Leu Gly Gln Asp Thr Leu Val Pro Pro Val Tyr Thr Val 
    370                 375                 380                 


Ser Gln Ala Arg Gly Ser Ser Pro Val Ser Leu Asp Leu Ile Ile Pro 
385                 390                 395                 400 


Phe Leu Arg Pro Gly Cys Cys Val Leu Val Trp Arg Ser Asp Val Gln 
                405                 410                 415     


Phe Ala Trp Lys His Leu Leu Cys Pro Asp Val Ser Tyr Arg His 
            420                 425                 430     


<210>  650
<211>  157
<212>  PRT
<213>  Homo Sapiens

<400>  650

Tyr Phe Gly Lys Leu Glu Ser Lys Leu Ser Val Ile Arg Asn Leu Asn 
1               5                   10                  15      


Asp Gln Val Leu Phe Ile Asp Gln Gly Asn Arg Pro Leu Phe Glu Asp 
            20                  25                  30          


Met Thr Asp Ser Asp Cys Arg Asp Asn Ala Pro Arg Thr Ile Phe Ile 
        35                  40                  45              


Ile Ser Met Tyr Lys Asp Ser Gln Pro Arg Gly Met Ala Val Thr Ile 
    50                  55                  60                  


Ser Val Lys Cys Glu Lys Ile Ser Thr Leu Ser Cys Glu Asn Lys Ile 
65                  70                  75                  80  


Ile Ser Phe Lys Glu Met Asn Pro Pro Asp Asn Ile Lys Asp Thr Lys 
                85                  90                  95      


Ser Asp Ile Ile Phe Phe Gln Arg Ser Val Pro Gly His Asp Asn Lys 
            100                 105                 110         


Met Gln Phe Glu Ser Ser Ser Tyr Glu Gly Tyr Phe Leu Ala Cys Glu 
        115                 120                 125             


Lys Glu Arg Asp Leu Phe Lys Leu Ile Leu Lys Lys Glu Asp Glu Leu 
    130                 135                 140                 


Gly Asp Arg Ser Ile Met Phe Thr Val Gln Asn Glu Asp 
145                 150                 155         


<210>  651
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  651

Thr Pro Val Ser Gln Thr Thr Thr Ala Ala Thr Ala Ser Val Arg Ser 
1               5                   10                  15      


Thr Lys Asp Pro Cys Pro Ser Gln Pro Pro Val Phe Pro Ala Ala Lys 
            20                  25                  30          


Gln Cys Pro Ala Leu Glu Val Thr Trp Pro Glu Val Glu Val Pro Leu 
        35                  40                  45              


Asn Gly Thr Leu Ser Leu Ser Cys Val Ala Cys Ser Arg Phe Pro Asn 
    50                  55                  60                  


Phe Ser Ile Leu Tyr Trp Leu Gly Asn Gly Ser Phe Ile Glu His Leu 
65                  70                  75                  80  


Pro Gly Arg Leu Trp Glu Gly Ser Thr Ser Arg Glu Arg Gly Ser Thr 
                85                  90                  95      


Gly Thr Gln Leu Cys Lys Ala Leu Val Leu Glu Gln Leu Thr Pro Ala 
            100                 105                 110         


Leu His Ser Thr Asn Phe Ser Cys Val Leu Val Asp Pro Glu Gln Val 
        115                 120                 125             


Val Gln Arg His Val Val Leu Ala Gln Leu Trp Ala Gly Leu Arg Ala 
    130                 135                 140                 


Thr Leu Pro Pro Thr Gln Glu Ala Leu Pro Ser Ser His Ser Ser Pro 
145                 150                 155                 160 


Gln Gln Gln Gly 
                


<210>  652
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  652

Cys Thr Ser Arg Pro His Ile Thr Val Val Glu Gly Glu Pro Phe Tyr 
1               5                   10                  15      


Leu Lys His Cys Ser Cys Ser Leu Ala His Glu Ile Glu Thr Thr Thr 
            20                  25                  30          


Lys Ser Trp Tyr Lys Ser Ser Gly Ser Gln Glu His Val Glu Leu Asn 
        35                  40                  45              


Pro Arg Ser Ser Ser Arg Ile Ala Leu His Asp Cys Val Leu Glu Phe 
    50                  55                  60                  


Trp Pro Val Glu Leu Asn Asp Thr Gly Ser Tyr Phe Phe Gln Met Lys 
65                  70                  75                  80  


Asn Tyr Thr Gln Lys Trp Lys Leu Asn Val Ile Arg Arg Asn Lys His 
                85                  90                  95      


Ser Cys Phe Thr Glu Arg Gln Val Thr Ser Lys Ile Val Glu Val Lys 
            100                 105                 110         


Lys Phe Phe Gln Ile Thr Cys Glu Asn Ser Tyr Tyr Gln Thr Leu Val 
        115                 120                 125             


Asn Ser Thr Ser Leu Tyr Lys Asn Cys Lys Lys Leu Leu Leu Glu Asn 
    130                 135                 140                 


Asn Lys Asn Pro Thr Ile Lys Lys Asn Ala Glu Phe Glu Asp Gln Gly 
145                 150                 155                 160 


Tyr Tyr Ser Cys Val His Phe Leu His His Asn Gly Lys Leu Phe Asn 
                165                 170                 175     


Ile Thr Lys Thr Phe Asn Ile Thr Ile Val Glu Asp Arg Ser Asn Ile 
            180                 185                 190         


Val Pro Val Leu Leu Gly Pro Lys Leu Asn His Val Ala Val Glu Leu 
        195                 200                 205             


Gly Lys Asn Val Arg Leu Asn Cys Ser Ala Leu Leu Asn Glu Glu Asp 
    210                 215                 220                 


Val Ile Tyr Trp Met Phe Gly Glu Glu Asn Gly Ser Asp Pro Asn Ile 
225                 230                 235                 240 


His Glu Glu Lys Glu Met Arg Ile Met Thr Pro Glu Gly Lys Trp His 
                245                 250                 255     


Ala Ser Lys Val Leu Arg Ile Glu Asn Ile Gly Glu Ser Asn Leu Asn 
            260                 265                 270         


Val Leu Tyr Asn Cys Thr Val Ala Ser Thr Gly Gly Thr Asp Thr Lys 
        275                 280                 285             


Ser Phe Ile Leu Val Arg Lys Ala Asp Met Ala Asp Ile Pro Gly His 
    290                 295                 300                 


Val Phe Thr Arg 
305             


<210>  653
<211>  337
<212>  PRT
<213>  Homo Sapiens

<400>  653

Phe Asn Ile Ser Gly Cys Ser Thr Lys Lys Leu Leu Trp Thr Tyr Ser 
1               5                   10                  15      


Thr Arg Ser Glu Glu Glu Phe Val Leu Phe Cys Asp Leu Pro Glu Pro 
            20                  25                  30          


Gln Lys Ser His Phe Cys His Arg Asn Arg Leu Ser Pro Lys Gln Val 
        35                  40                  45              


Pro Glu His Leu Pro Phe Met Gly Ser Asn Asp Leu Ser Asp Val Gln 
    50                  55                  60                  


Trp Tyr Gln Gln Pro Ser Asn Gly Asp Pro Leu Glu Asp Ile Arg Lys 
65                  70                  75                  80  


Ser Tyr Pro His Ile Ile Gln Asp Lys Cys Thr Leu His Phe Leu Thr 
                85                  90                  95      


Pro Gly Val Asn Asn Ser Gly Ser Tyr Ile Cys Arg Pro Lys Met Ile 
            100                 105                 110         


Lys Ser Pro Tyr Asp Val Ala Cys Cys Val Lys Met Ile Leu Glu Val 
        115                 120                 125             


Lys Pro Gln Thr Asn Ala Ser Cys Glu Tyr Ser Ala Ser His Lys Gln 
    130                 135                 140                 


Asp Leu Leu Leu Gly Ser Thr Gly Ser Ile Ser Cys Pro Ser Leu Ser 
145                 150                 155                 160 


Cys Gln Ser Asp Ala Gln Ser Pro Ala Val Thr Trp Tyr Lys Asn Gly 
                165                 170                 175     


Lys Leu Leu Ser Val Glu Arg Ser Asn Arg Ile Val Val Asp Glu Val 
            180                 185                 190         


Tyr Asp Tyr His Gln Gly Thr Tyr Val Cys Asp Tyr Thr Gln Ser Asp 
        195                 200                 205             


Thr Val Ser Ser Trp Thr Val Arg Ala Val Val Gln Val Arg Thr Ile 
    210                 215                 220                 


Val Gly Asp Thr Lys Leu Lys Pro Asp Ile Leu Asp Pro Val Glu Asp 
225                 230                 235                 240 


Thr Leu Glu Val Glu Leu Gly Lys Pro Leu Thr Ile Ser Cys Lys Ala 
                245                 250                 255     


Arg Phe Gly Phe Glu Arg Val Phe Asn Pro Val Ile Lys Trp Tyr Ile 
            260                 265                 270         


Lys Asp Ser Asp Leu Glu Trp Glu Val Ser Val Pro Glu Ala Lys Ser 
        275                 280                 285             


Ile Lys Ser Thr Leu Lys Asp Glu Ile Ile Glu Arg Asn Ile Ile Leu 
    290                 295                 300                 


Glu Lys Val Thr Gln Arg Asp Leu Arg Arg Lys Phe Val Cys Phe Val 
305                 310                 315                 320 


Gln Asn Ser Ile Gly Asn Thr Thr Gln Ser Val Gln Leu Lys Glu Lys 
                325                 330                 335     


Arg 
    


<210>  654
<211>  153
<212>  PRT
<213>  Homo Sapiens

<400>  654

Leu Arg Arg Cys Leu Ile Ser Thr Asp Met His His Ile Glu Glu Ser 
1               5                   10                  15      


Phe Gln Glu Ile Lys Arg Ala Ile Gln Ala Lys Asp Thr Phe Pro Asn 
            20                  25                  30          


Val Thr Ile Leu Ser Thr Leu Glu Thr Leu Gln Ile Ile Lys Pro Leu 
        35                  40                  45              


Asp Val Cys Cys Val Thr Lys Asn Leu Leu Ala Phe Tyr Val Asp Arg 
    50                  55                  60                  


Val Phe Lys Asp His Gln Glu Pro Asn Pro Lys Ile Leu Arg Lys Ile 
65                  70                  75                  80  


Ser Ser Ile Ala Asn Ser Phe Leu Tyr Met Gln Lys Thr Leu Arg Gln 
                85                  90                  95      


Cys Gln Glu Gln Arg Gln Cys His Cys Arg Gln Glu Ala Thr Asn Ala 
            100                 105                 110         


Thr Arg Val Ile His Asp Asn Tyr Asp Gln Leu Glu Val His Ala Ala 
        115                 120                 125             


Ala Ile Lys Ser Leu Gly Glu Leu Asp Val Phe Leu Ala Trp Ile Asn 
    130                 135                 140                 


Lys Asn His Glu Val Met Phe Ser Ala 
145                 150             


<210>  655
<211>  159
<212>  PRT
<213>  Homo Sapiens

<400>  655

Ser Ala Pro Phe Ser Phe Leu Ser Asn Val Lys Tyr Asn Phe Met Arg 
1               5                   10                  15      


Ile Ile Lys Tyr Glu Phe Ile Leu Asn Asp Ala Leu Asn Gln Ser Ile 
            20                  25                  30          


Ile Arg Ala Asn Asp Gln Tyr Leu Thr Ala Ala Ala Leu His Asn Leu 
        35                  40                  45              


Asp Glu Ala Val Lys Phe Asp Met Gly Ala Tyr Lys Ser Ser Lys Asp 
    50                  55                  60                  


Asp Ala Lys Ile Thr Val Ile Leu Arg Ile Ser Lys Thr Gln Leu Tyr 
65                  70                  75                  80  


Val Thr Ala Gln Asp Glu Asp Gln Pro Val Leu Leu Lys Glu Met Pro 
                85                  90                  95      


Glu Ile Pro Lys Thr Ile Thr Gly Ser Glu Thr Asn Leu Leu Phe Phe 
            100                 105                 110         


Trp Glu Thr His Gly Thr Lys Asn Tyr Phe Thr Ser Val Ala His Pro 
        115                 120                 125             


Asn Leu Phe Ile Ala Thr Lys Gln Asp Tyr Trp Val Cys Leu Ala Gly 
    130                 135                 140                 


Gly Pro Pro Ser Ile Thr Asp Phe Gln Ile Leu Glu Asn Gln Ala 
145                 150                 155                 


<210>  656
<211>  153
<212>  PRT
<213>  Homo Sapiens

<400>  656

Ala Pro Val Arg Ser Leu Asn Cys Thr Leu Arg Asp Ser Gln Gln Lys 
1               5                   10                  15      


Ser Leu Val Met Ser Gly Pro Tyr Glu Leu Lys Ala Leu His Leu Gln 
            20                  25                  30          


Gly Gln Asp Met Glu Gln Gln Val Val Phe Ser Met Ser Phe Val Gln 
        35                  40                  45              


Gly Glu Glu Ser Asn Asp Lys Ile Pro Val Ala Leu Gly Leu Lys Glu 
    50                  55                  60                  


Lys Asn Leu Tyr Leu Ser Cys Val Leu Lys Asp Asp Lys Pro Thr Leu 
65                  70                  75                  80  


Gln Leu Glu Ser Val Asp Pro Lys Asn Tyr Pro Lys Lys Lys Met Glu 
                85                  90                  95      


Lys Arg Phe Val Phe Asn Lys Ile Glu Ile Asn Asn Lys Leu Glu Phe 
            100                 105                 110         


Glu Ser Ala Gln Phe Pro Asn Trp Tyr Ile Ser Thr Ser Gln Ala Glu 
        115                 120                 125             


Asn Met Pro Val Phe Leu Gly Gly Thr Lys Gly Gly Gln Asp Ile Thr 
    130                 135                 140                 


Asp Phe Thr Met Gln Phe Val Ser Ser 
145                 150             


<210>  657
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  657

Met Cys Ser Leu Pro Met Ala Arg Tyr Tyr Ile Ile Lys Tyr Ala Asp 
1               5                   10                  15      


Gln Lys Ala Leu Tyr Thr Arg Asp Gly Gln Leu Leu Val Gly Asp Pro 
            20                  25                  30          


Val Ala Asp Asn Cys Cys Ala Glu Lys Ile Cys Thr Leu Pro Asn Arg 
        35                  40                  45              


Gly Leu Asp Arg Thr Lys Val Pro Ile Phe Leu Gly Ile Gln Gly Gly 
    50                  55                  60                  


Ser Arg Cys Leu Ala Cys Val Glu Thr Glu Glu Gly Pro Ser Leu Gln 
65                  70                  75                  80  


Leu Glu Asp Val Asn Ile Glu Glu Leu Tyr Lys Gly Gly Glu Glu Ala 
                85                  90                  95      


Thr Arg Phe Thr Phe Phe Gln Ser Ser Ser Gly Ser Ala Phe Arg Leu 
            100                 105                 110         


Glu Ala Ala Ala Trp Pro Gly Trp Phe Leu Cys Gly Pro Ala Glu Pro 
        115                 120                 125             


Gln Gln Pro Val Gln Leu Thr Lys Glu Ser Glu Pro Ser Ala Arg Thr 
    130                 135                 140                 


Lys Phe Tyr Phe Glu Gln Ser Trp 
145                 150         


<210>  658
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  658

Val Leu Ser Gly Ala Leu Cys Phe Arg Met Lys Asp Ser Ala Leu Lys 
1               5                   10                  15      


Val Leu Tyr Leu His Asn Asn Gln Leu Leu Ala Gly Gly Leu His Ala 
            20                  25                  30          


Gly Lys Val Ile Lys Gly Glu Glu Ile Ser Val Val Pro Asn Arg Trp 
        35                  40                  45              


Leu Asp Ala Ser Leu Ser Pro Val Ile Leu Gly Val Gln Gly Gly Ser 
    50                  55                  60                  


Gln Cys Leu Ser Cys Gly Val Gly Gln Glu Pro Thr Leu Thr Leu Glu 
65                  70                  75                  80  


Pro Val Asn Ile Met Glu Leu Tyr Leu Gly Ala Lys Glu Ser Lys Ser 
                85                  90                  95      


Phe Thr Phe Tyr Arg Arg Asp Met Gly Leu Thr Ser Ser Phe Glu Ser 
            100                 105                 110         


Ala Ala Tyr Pro Gly Trp Phe Leu Cys Thr Val Pro Glu Ala Asp Gln 
        115                 120                 125             


Pro Val Arg Leu Thr Gln Leu Pro Glu Asn Gly Gly Trp Asn Ala Pro 
    130                 135                 140                 


Ile Thr Asp Phe Tyr Phe Gln Gln Cys Asp 
145                 150                 


<210>  659
<211>  153
<212>  PRT
<213>  Homo Sapiens

<400>  659

Lys Ile Asp Thr Pro Gln Gln Gly Ser Ile Gln Asp Ile Asn His Arg 
1               5                   10                  15      


Val Trp Val Leu Gln Asp Gln Thr Leu Ile Ala Val Pro Arg Lys Asp 
            20                  25                  30          


Arg Met Ser Pro Val Thr Ile Ala Leu Ile Ser Cys Arg His Val Glu 
        35                  40                  45              


Thr Leu Glu Lys Asp Arg Gly Asn Pro Ile Tyr Leu Gly Leu Asn Gly 
    50                  55                  60                  


Leu Asn Leu Cys Leu Met Cys Ala Lys Val Gly Asp Gln Pro Thr Leu 
65                  70                  75                  80  


Gln Leu Lys Glu Lys Asp Ile Met Asp Leu Tyr Asn Gln Pro Glu Pro 
                85                  90                  95      


Val Lys Ser Phe Leu Phe Tyr His Ser Gln Ser Gly Arg Asn Ser Thr 
            100                 105                 110         


Phe Glu Ser Val Ala Phe Pro Gly Trp Phe Ile Ala Val Ser Ser Glu 
        115                 120                 125             


Gly Gly Cys Pro Leu Ile Leu Thr Gln Glu Leu Gly Lys Ala Asn Thr 
    130                 135                 140                 


Thr Asp Phe Gly Leu Thr Met Leu Phe 
145                 150             


<210>  660
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  660

Val His Thr Ser Pro Lys Val Lys Asn Leu Asn Pro Lys Lys Phe Ser 
1               5                   10                  15      


Ile His Asp Gln Asp His Lys Val Leu Val Leu Asp Ser Gly Asn Leu 
            20                  25                  30          


Ile Ala Val Pro Asp Lys Asn Tyr Ile Arg Pro Glu Ile Phe Phe Ala 
        35                  40                  45              


Leu Ala Ser Ser Leu Ser Ser Ala Ser Ala Glu Lys Gly Ser Pro Ile 
    50                  55                  60                  


Leu Leu Gly Val Ser Lys Gly Glu Phe Cys Leu Tyr Cys Asp Lys Asp 
65                  70                  75                  80  


Lys Gly Gln Ser His Pro Ser Leu Gln Leu Lys Lys Glu Lys Leu Met 
                85                  90                  95      


Lys Leu Ala Ala Gln Lys Glu Ser Ala Arg Arg Pro Phe Ile Phe Tyr 
            100                 105                 110         


Arg Ala Gln Val Gly Ser Trp Asn Met Leu Glu Ser Ala Ala His Pro 
        115                 120                 125             


Gly Trp Phe Ile Cys Thr Ser Cys Asn Cys Asn Glu Pro Val Gly Val 
    130                 135                 140                 


Thr Asp Lys Phe Glu Asn Arg Lys His Ile Glu Phe Ser Phe Gln Pro 
145                 150                 155                 160 


Val Cys Lys Ala Glu Met Ser Pro Ser Glu Val Ser Asp 
                165                 170             


<210>  661
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  661

Ser Met Cys Lys Pro Ile Thr Gly Thr Ile Asn Asp Leu Asn Gln Gln 
1               5                   10                  15      


Val Trp Thr Leu Gln Gly Gln Asn Leu Val Ala Val Pro Arg Ser Asp 
            20                  25                  30          


Ser Val Thr Pro Val Thr Val Ala Val Ile Thr Cys Lys Tyr Pro Glu 
        35                  40                  45              


Ala Leu Glu Gln Gly Arg Gly Asp Pro Ile Tyr Leu Gly Ile Gln Asn 
    50                  55                  60                  


Pro Glu Met Cys Leu Tyr Cys Glu Lys Val Gly Glu Gln Pro Thr Leu 
65                  70                  75                  80  


Gln Leu Lys Glu Gln Lys Ile Met Asp Leu Tyr Gly Gln Pro Glu Pro 
                85                  90                  95      


Val Lys Pro Phe Leu Phe Tyr Arg Ala Lys Thr Gly Arg Thr Ser Thr 
            100                 105                 110         


Leu Glu Ser Val Ala Phe Pro Asp Trp Phe Ile Ala Ser Ser Lys Arg 
        115                 120                 125             


Asp Gln Pro Ile Ile Leu Thr Ser Glu Leu Gly Lys Ser Tyr Asn Thr 
    130                 135                 140                 


Ala Phe Glu Leu Asn Ile Asn Asp 
145                 150         


<210>  662
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  662

Leu Glu Ala Asp Lys Cys Lys Glu Arg Glu Glu Lys Ile Ile Leu Val 
1               5                   10                  15      


Ser Ser Ala Asn Glu Ile Asp Val Arg Pro Cys Pro Leu Asn Pro Asn 
            20                  25                  30          


Glu His Lys Gly Thr Ile Thr Trp Tyr Lys Asp Asp Ser Lys Thr Pro 
        35                  40                  45              


Val Ser Thr Glu Gln Ala Ser Arg Ile His Gln His Lys Glu Lys Leu 
    50                  55                  60                  


Trp Phe Val Pro Ala Lys Val Glu Asp Ser Gly His Tyr Tyr Cys Val 
65                  70                  75                  80  


Val Arg Asn Ser Ser Tyr Cys Leu Arg Ile Lys Ile Ser Ala Lys Phe 
                85                  90                  95      


Val Glu Asn Glu Pro Asn Leu Cys Tyr Asn Ala Gln Ala Ile Phe Lys 
            100                 105                 110         


Gln Lys Leu Pro Val Ala Gly Asp Gly Gly Leu Val Cys Pro Tyr Met 
        115                 120                 125             


Glu Phe Phe Lys Asn Glu Asn Asn Glu Leu Pro Lys Leu Gln Trp Tyr 
    130                 135                 140                 


Lys Asp Cys Lys Pro Leu Leu Leu Asp Asn Ile His Phe Ser Gly Val 
145                 150                 155                 160 


Lys Asp Arg Leu Ile Val Met Asn Val Ala Glu Lys His Arg Gly Asn 
                165                 170                 175     


Tyr Thr Cys His Ala Ser Tyr Thr Tyr Leu Gly Lys Gln Tyr Pro Ile 
            180                 185                 190         


Thr Arg Val Ile Glu Phe Ile Thr Leu Glu Glu Asn Lys Pro Thr Arg 
        195                 200                 205             


Pro Val Ile Val Ser Pro Ala Asn Glu Thr Met Glu Val Asp Leu Gly 
    210                 215                 220                 


Ser Gln Ile Gln Leu Ile Cys Asn Val Thr Gly Gln Leu Ser Asp Ile 
225                 230                 235                 240 


Ala Tyr Trp Lys Trp Asn Gly Ser Val Ile Asp Glu Asp Asp Pro Val 
                245                 250                 255     


Leu Gly Glu Asp Tyr Tyr Ser Val Glu Asn Pro Ala Asn Lys Arg Arg 
            260                 265                 270         


Ser Thr Leu Ile Thr Val Leu Asn Ile Ser Glu Ile Glu Ser Arg Phe 
        275                 280                 285             


Tyr Lys His Pro Phe Thr Cys Phe Ala Lys Asn Thr His Gly Ile Asp 
    290                 295                 300                 


Ala Ala Tyr Ile Gln Leu Ile Tyr Pro Val Thr Asn Phe Gln Lys 
305                 310                 315                 


<210>  663
<211>  330
<212>  PRT
<213>  Homo Sapiens

<400>  663

Phe Thr Leu Gln Pro Ala Ala His Thr Gly Ala Ala Arg Ser Cys Arg 
1               5                   10                  15      


Phe Arg Gly Arg His Tyr Lys Arg Glu Phe Arg Leu Glu Gly Glu Pro 
            20                  25                  30          


Val Ala Leu Arg Cys Pro Gln Val Pro Tyr Trp Leu Trp Ala Ser Val 
        35                  40                  45              


Ser Pro Arg Ile Asn Leu Thr Trp His Lys Asn Asp Ser Ala Arg Thr 
    50                  55                  60                  


Val Pro Gly Glu Glu Glu Thr Arg Met Trp Ala Gln Asp Gly Ala Leu 
65                  70                  75                  80  


Trp Leu Leu Pro Ala Leu Gln Glu Asp Ser Gly Thr Tyr Val Cys Thr 
                85                  90                  95      


Thr Arg Asn Ala Ser Tyr Cys Asp Lys Met Ser Ile Glu Leu Arg Val 
            100                 105                 110         


Phe Glu Asn Thr Asp Ala Phe Leu Pro Phe Ile Ser Tyr Pro Gln Ile 
        115                 120                 125             


Leu Thr Leu Ser Thr Ser Gly Val Leu Val Cys Pro Asp Leu Ser Glu 
    130                 135                 140                 


Phe Thr Arg Asp Lys Thr Asp Val Lys Ile Gln Trp Tyr Lys Asp Ser 
145                 150                 155                 160 


Leu Leu Leu Asp Lys Asp Asn Glu Lys Phe Leu Ser Val Arg Gly Thr 
                165                 170                 175     


Thr His Leu Leu Val His Asp Val Ala Leu Glu Asp Ala Gly Tyr Tyr 
            180                 185                 190         


Arg Cys Val Leu Thr Phe Ala His Glu Gly Gln Gln Tyr Asn Ile Thr 
        195                 200                 205             


Arg Ser Ile Glu Leu Arg Ile Lys Lys Lys Lys Glu Glu Thr Ile Pro 
    210                 215                 220                 


Val Ile Ile Ser Pro Leu Lys Thr Ile Ser Ala Ser Leu Gly Ser Arg 
225                 230                 235                 240 


Leu Thr Ile Pro Cys Lys Val Phe Leu Gly Thr Gly Thr Pro Leu Thr 
                245                 250                 255     


Thr Met Leu Trp Trp Thr Ala Asn Asp Thr His Ile Glu Ser Ala Tyr 
            260                 265                 270         


Pro Gly Gly Arg Val Thr Glu Gly Pro Arg Gln Glu Tyr Ser Glu Asn 
        275                 280                 285             


Asn Glu Asn Tyr Ile Glu Val Pro Leu Ile Phe Asp Pro Val Thr Arg 
    290                 295                 300                 


Glu Asp Leu His Met Asp Phe Lys Cys Val Val His Asn Thr Leu Ser 
305                 310                 315                 320 


Phe Gln Thr Leu Arg Thr Thr Val Lys Glu 
                325                 330 


<210>  664
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  664

Ser Glu Arg Cys Asp Asp Trp Gly Leu Asp Thr Met Arg Gln Ile Gln 
1               5                   10                  15      


Val Phe Glu Asp Glu Pro Ala Arg Ile Lys Cys Pro Leu Phe Glu His 
            20                  25                  30          


Phe Leu Lys Phe Asn Tyr Ser Thr Ala His Ser Ala Gly Leu Thr Leu 
        35                  40                  45              


Ile Trp Tyr Trp Thr Arg Gln Asp Arg Asp Leu Glu Glu Pro Ile Asn 
    50                  55                  60                  


Phe Arg Leu Pro Glu Asn Arg Ile Ser Lys Glu Lys Asp Val Leu Trp 
65                  70                  75                  80  


Phe Arg Pro Thr Leu Leu Asn Asp Thr Gly Asn Tyr Thr Cys Met Leu 
                85                  90                  95      


Arg Asn Thr Thr Tyr Cys Ser Lys Val Ala Phe Pro Leu Glu Val Val 
            100                 105                 110         


Gln Lys Asp Ser Cys Phe Asn Ser Pro Met Lys Leu Pro Val His Lys 
        115                 120                 125             


Leu Tyr Ile Glu Tyr Gly Ile Gln Arg Ile Thr Cys Pro Asn Val Asp 
    130                 135                 140                 


Gly Tyr Phe Pro Ser Ser Val Lys Pro Thr Ile Thr Trp Tyr Met Gly 
145                 150                 155                 160 


Cys Tyr Lys Ile Gln Asn Phe Asn Asn Val Ile Pro Glu Gly Met Asn 
                165                 170                 175     


Leu Ser Phe Leu Ile Ala Leu Ile Ser Asn Asn Gly Asn Tyr Thr Cys 
            180                 185                 190         


Val Val Thr Tyr Pro Glu Asn Gly Arg Thr Phe His Leu Thr Arg Thr 
        195                 200                 205             


Leu Thr Val Lys Val Val Gly Ser Pro Lys Asn Ala Val Pro Pro Val 
    210                 215                 220                 


Ile His Ser Pro Asn Asp His Val Val Tyr Glu Lys Glu Pro Gly Glu 
225                 230                 235                 240 


Glu Leu Leu Ile Pro Cys Thr Val Tyr Phe Ser Phe Leu Met Asp Ser 
                245                 250                 255     


Arg Asn Glu Val Trp Trp Thr Ile Asp Gly Lys Lys Pro Asp Asp Ile 
            260                 265                 270         


Thr Ile Asp Val Thr Ile Asn Glu Ser Ile Ser His Ser Arg Thr Glu 
        275                 280                 285             


Asp Glu Thr Arg Thr Gln Ile Leu Ser Ile Lys Lys Val Thr Ser Glu 
    290                 295                 300                 


Asp Leu Lys Arg Ser Tyr Val Cys His Ala Arg Ser Ala Lys Gly Glu 
305                 310                 315                 320 


Val Ala Lys Ala Ala Lys Val Lys Gln Lys Gly Asn Arg Cys Gly Gln 
                325                 330                 335     


<210>  665
<211>  339
<212>  PRT
<213>  Homo Sapiens

<400>  665

Leu Lys Val Val Thr Lys Arg Gly Ser Ala Asp Gly Cys Thr Asp Trp 
1               5                   10                  15      


Ser Ile Asp Ile Lys Lys Tyr Gln Val Leu Val Gly Glu Pro Val Arg 
            20                  25                  30          


Ile Lys Cys Ala Leu Phe Tyr Gly Tyr Ile Arg Thr Asn Tyr Ser Leu 
        35                  40                  45              


Ala Gln Ser Ala Gly Leu Ser Leu Met Trp Tyr Lys Ser Ser Gly Pro 
    50                  55                  60                  


Gly Asp Phe Glu Glu Pro Ile Ala Phe Asp Gly Ser Arg Met Ser Lys 
65                  70                  75                  80  


Glu Glu Asp Ser Ile Trp Phe Arg Pro Thr Leu Leu Gln Asp Ser Gly 
                85                  90                  95      


Leu Tyr Ala Cys Val Ile Arg Asn Ser Thr Tyr Cys Met Lys Val Ser 
            100                 105                 110         


Ile Ser Leu Thr Val Gly Glu Asn Asp Thr Gly Leu Cys Tyr Asn Ser 
        115                 120                 125             


Lys Met Lys Tyr Phe Glu Lys Ala Glu Leu Ser Lys Ser Lys Glu Ile 
    130                 135                 140                 


Ser Cys Arg Asp Ile Glu Asp Phe Leu Leu Pro Thr Arg Glu Pro Glu 
145                 150                 155                 160 


Ile Leu Trp Tyr Lys Glu Cys Arg Thr Lys Thr Trp Arg Pro Ser Ile 
                165                 170                 175     


Val Phe Lys Arg Asp Thr Leu Leu Ile Arg Glu Val Arg Glu Asp Asp 
            180                 185                 190         


Ile Gly Asn Tyr Thr Cys Glu Leu Lys Tyr Gly Gly Phe Val Val Arg 
        195                 200                 205             


Arg Thr Thr Glu Leu Thr Val Thr Ala Pro Leu Thr Asp Lys Pro Pro 
    210                 215                 220                 


Lys Leu Leu Tyr Pro Met Glu Ser Lys Leu Thr Ile Gln Glu Thr Gln 
225                 230                 235                 240 


Leu Gly Asp Ser Ala Asn Leu Thr Cys Arg Ala Phe Phe Gly Tyr Ser 
                245                 250                 255     


Gly Asp Val Ser Pro Leu Ile Tyr Trp Met Lys Gly Glu Lys Phe Ile 
            260                 265                 270         


Glu Asp Leu Asp Glu Asn Arg Val Trp Glu Ser Asp Ile Arg Ile Leu 
        275                 280                 285             


Lys Glu His Leu Gly Glu Gln Glu Val Ser Ile Ser Leu Ile Val Asp 
    290                 295                 300                 


Ser Val Glu Glu Gly Asp Leu Gly Asn Tyr Ser Cys Tyr Val Glu Asn 
305                 310                 315                 320 


Gly Asn Gly Arg Arg His Ala Ser Val Leu Leu His Lys Arg Glu Leu 
                325                 330                 335     


Met Tyr Thr 
            


<210>  666
<211>  338
<212>  PRT
<213>  Homo Sapiens

<400>  666

Thr Asn Leu Lys Met Val Ser Lys Arg Asn Ser Val Asp Gly Cys Ile 
1               5                   10                  15      


Asp Trp Ser Val Asp Leu Lys Thr Tyr Met Ala Leu Ala Gly Glu Pro 
            20                  25                  30          


Val Arg Val Lys Cys Ala Leu Phe Tyr Ser Tyr Ile Arg Thr Asn Tyr 
        35                  40                  45              


Ser Thr Ala Gln Ser Thr Gly Leu Arg Leu Met Trp Tyr Lys Asn Lys 
    50                  55                  60                  


Gly Asp Leu Glu Glu Pro Ile Ile Phe Ser Glu Val Arg Met Ser Lys 
65                  70                  75                  80  


Glu Glu Asp Ser Ile Trp Phe His Ser Ala Glu Ala Gln Asp Ser Gly 
                85                  90                  95      


Phe Tyr Thr Cys Val Leu Arg Asn Ser Thr Tyr Cys Met Lys Val Ser 
            100                 105                 110         


Met Ser Leu Thr Val Ala Glu Asn Glu Ser Gly Leu Cys Tyr Asn Ser 
        115                 120                 125             


Arg Ile Arg Tyr Leu Glu Lys Ser Glu Val Thr Lys Arg Lys Glu Ile 
    130                 135                 140                 


Ser Cys Pro Asp Met Asp Asp Phe Lys Lys Ser Asp Gln Glu Pro Asp 
145                 150                 155                 160 


Val Val Trp Tyr Lys Glu Cys Lys Pro Lys Met Trp Arg Ser Ile Ile 
                165                 170                 175     


Ile Gln Lys Gly Asn Ala Leu Leu Ile Gln Glu Val Gln Glu Glu Asp 
            180                 185                 190         


Gly Gly Asn Tyr Thr Cys Glu Leu Lys Tyr Glu Gly Lys Leu Val Arg 
        195                 200                 205             


Arg Thr Thr Glu Leu Lys Val Thr Ala Leu Leu Thr Asp Lys Pro Pro 
    210                 215                 220                 


Lys Pro Leu Phe Pro Met Glu Asn Gln Pro Ser Val Ile Asp Val Gln 
225                 230                 235                 240 


Leu Gly Lys Pro Leu Asn Ile Pro Cys Lys Ala Phe Phe Gly Phe Ser 
                245                 250                 255     


Gly Glu Ser Gly Pro Met Ile Tyr Trp Met Lys Gly Glu Lys Phe Ile 
            260                 265                 270         


Glu Glu Leu Ala Gly His Ile Arg Glu Gly Glu Ile Arg Leu Leu Lys 
        275                 280                 285             


Glu His Leu Gly Glu Lys Glu Val Glu Leu Ala Leu Ile Phe Asp Ser 
    290                 295                 300                 


Val Val Glu Ala Asp Leu Ala Asn Tyr Thr Cys His Val Glu Asn Arg 
305                 310                 315                 320 


Asn Gly Arg Lys His Ala Ser Val Leu Leu Arg Lys Lys Asp Leu Ile 
                325                 330                 335     


Tyr Lys 
        


<210>  667
<211>  310
<212>  PRT
<213>  Homo Sapiens

<400>  667

Lys Phe Ser Lys Gln Ser Trp Gly Leu Glu Asn Glu Ala Leu Ile Val 
1               5                   10                  15      


Arg Cys Pro Arg Gln Gly Lys Pro Ser Tyr Thr Val Asp Trp Tyr Tyr 
            20                  25                  30          


Ser Gln Thr Asn Lys Ser Ile Pro Thr Gln Glu Arg Asn Arg Val Phe 
        35                  40                  45              


Ala Ser Gly Gln Leu Leu Lys Phe Leu Pro Ala Ala Val Ala Asp Ser 
    50                  55                  60                  


Gly Ile Tyr Thr Cys Ile Val Arg Ser Pro Thr Phe Asn Arg Thr Gly 
65                  70                  75                  80  


Tyr Ala Asn Val Thr Ile Tyr Lys Lys Gln Ser Asp Cys Asn Val Pro 
                85                  90                  95      


Asp Tyr Leu Met Tyr Ser Thr Val Ser Gly Ser Glu Lys Asn Ser Lys 
            100                 105                 110         


Ile Tyr Cys Pro Thr Ile Asp Leu Tyr Asn Trp Thr Ala Pro Leu Glu 
        115                 120                 125             


Trp Phe Lys Asn Cys Gln Ala Leu Gln Gly Ser Arg Tyr Arg Ala His 
    130                 135                 140                 


Lys Ser Phe Leu Val Ile Asp Asn Val Met Thr Glu Asp Ala Gly Asp 
145                 150                 155                 160 


Tyr Thr Cys Lys Phe Ile His Asn Glu Asn Gly Ala Asn Tyr Ser Val 
                165                 170                 175     


Thr Ala Thr Arg Ser Phe Thr Val Lys Asp Glu Gln Gly Phe Ser Leu 
            180                 185                 190         


Phe Pro Val Ile Gly Ala Pro Ala Gln Asn Glu Ile Lys Glu Val Glu 
        195                 200                 205             


Ile Gly Lys Asn Ala Asn Leu Thr Cys Ser Ala Cys Phe Gly Lys Gly 
    210                 215                 220                 


Thr Gln Phe Leu Ala Ala Val Leu Trp Gln Leu Asn Gly Thr Lys Ile 
225                 230                 235                 240 


Thr Asp Phe Gly Glu Pro Arg Ile Gln Gln Glu Glu Gly Gln Asn Gln 
                245                 250                 255     


Ser Phe Ser Asn Gly Leu Ala Cys Leu Asp Met Val Leu Arg Ile Ala 
            260                 265                 270         


Asp Val Lys Glu Glu Asp Leu Leu Leu Gln Tyr Asp Cys Leu Ala Leu 
        275                 280                 285             


Asn Leu His Gly Leu Arg Arg His Thr Val Arg Leu Ser Arg Lys Asn 
    290                 295                 300                 


Pro Ser Lys Glu Cys Phe 
305                 310 


<210>  668
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  668

Met Thr Gly Leu Val Ser Leu Ser Tyr Phe Pro Leu Ser Thr Arg Ser 
1               5                   10                  15      


Cys Ala Leu Gln Ser Cys Ser Pro Val Trp Gly Cys Gly Pro Cys Cys 
            20                  25                  30          


Ser Ala Gly Cys Pro Ser Pro Phe His Cys Leu Ser Gln Gln Asp Cys 
        35                  40                  45              


Asn Glu Ile Lys Gly Glu Arg Phe Thr Val Leu Glu Thr Arg Leu Leu 
    50                  55                  60                  


Val Ser Asn Val Ser Ala Glu Asp Arg Gly Asn Tyr Ala Cys Gln Ala 
65                  70                  75                  80  


Ile Leu Thr His Ser Gly Lys Gln Tyr Glu Val Leu Asn Gly Ile Thr 
                85                  90                  95      


Val Ser Ile Lys Arg Ala Gly Tyr Gly Gly Ser Val Pro Lys Ile Ile 
            100                 105                 110         


Tyr Pro Lys Asn His Ser Ile Glu Val Gln Leu Gly Thr Thr Leu Ile 
        115                 120                 125             


Val Asp Cys Asn Val Thr Asp Thr Lys Asp Asn Thr Asn Leu Arg Cys 
    130                 135                 140                 


Trp Arg Val Asn Asn Thr Leu Val Asp Asp Tyr Tyr Asp Glu Ser Lys 
145                 150                 155                 160 


Arg Ile Arg Glu Gly Val Glu Thr His Val Ser Phe Arg Glu His Asn 
                165                 170                 175     


Leu Tyr Thr Val Asn Ile Thr Phe Leu Glu Val Lys Met Glu Asp Tyr 
            180                 185                 190         


Gly Leu Pro Phe Met Cys His Ala Gly Val Ser Thr Ala Tyr Ile Ile 
        195                 200                 205             


Leu Gln Leu Pro Ala Pro Asp Phe Arg 
    210                 215         


<210>  669
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  669

Arg Pro Ser Gly Arg Lys Ser Ser Lys Met Gln Ala Phe Arg Ile Trp 
1               5                   10                  15      


Asp Val Asn Gln Lys Thr Phe Tyr Leu Arg Asn Asn Gln Leu Val Ala 
            20                  25                  30          


Gly Tyr Leu Gln Gly Pro Asn Val Asn Leu Glu Glu Lys Ile Asp Val 
        35                  40                  45              


Val Pro Ile Glu Pro His Ala Leu Phe Leu Gly Ile His Gly Gly Lys 
    50                  55                  60                  


Met Cys Leu Ser Cys Val Lys Ser Gly Asp Glu Thr Arg Leu Gln Leu 
65                  70                  75                  80  


Glu Ala Val Asn Ile Thr Asp Leu Ser Glu Asn Arg Lys Gln Asp Lys 
                85                  90                  95      


Arg Phe Ala Phe Ile Arg Ser Asp Ser Gly Pro Thr Thr Ser Phe Glu 
            100                 105                 110         


Ser Ala Ala Cys Pro Gly Trp Phe Leu Cys Thr Ala Met Glu Ala Asp 
        115                 120                 125             


Gln Pro Val Ser Leu Thr Asn Met Pro Asp Glu Gly Val Met Val Thr 
    130                 135                 140                 


Lys Phe Tyr Phe Gln Glu Asp Glu 
145                 150         


<210>  670
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  670

Ala Pro Thr Ser Ser Ser Thr Lys Lys Thr Gln Leu Gln Leu Glu His 
1               5                   10                  15      


Leu Leu Leu Asp Leu Gln Met Ile Leu Asn Gly Ile Asn Asn Tyr Lys 
            20                  25                  30          


Asn Pro Lys Leu Thr Arg Met Leu Thr Phe Lys Phe Tyr Met Pro Lys 
        35                  40                  45              


Lys Ala Thr Glu Leu Lys His Leu Gln Cys Leu Glu Glu Glu Leu Lys 
    50                  55                  60                  


Pro Leu Glu Glu Val Leu Asn Leu Ala Gln Ser Lys Asn Phe His Leu 
65                  70                  75                  80  


Arg Pro Arg Asp Leu Ile Ser Asn Ile Asn Val Ile Val Leu Glu Leu 
                85                  90                  95      


Lys Gly Ser Glu Thr Thr Phe Met Cys Glu Tyr Ala Asp Glu Thr Ala 
            100                 105                 110         


Thr Ile Val Glu Phe Leu Asn Arg Trp Ile Thr Phe Cys Gln Ser Ile 
        115                 120                 125             


Ile Ser Thr Leu Thr 
    130             


<210>  671
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  671

Leu Lys Thr Leu Asn Leu Gly Ser Cys Val Ile Ala Thr Asn Leu Gln 
1               5                   10                  15      


Glu Ile Arg Asn Gly Phe Ser Glu Ile Arg Gly Ser Val Gln Ala Lys 
            20                  25                  30          


Asp Gly Asn Ile Asp Ile Arg Ile Leu Arg Arg Thr Glu Ser Leu Gln 
        35                  40                  45              


Asp Thr Lys Pro Ala Asn Arg Cys Cys Leu Leu Arg His Leu Leu Arg 
    50                  55                  60                  


Leu Tyr Leu Asp Arg Val Phe Lys Asn Tyr Gln Thr Pro Asp His Tyr 
65                  70                  75                  80  


Thr Leu Arg Lys Ile Ser Ser Leu Ala Asn Ser Phe Leu Thr Ile Lys 
                85                  90                  95      


Lys Asp Leu Arg Leu Cys His Ala His Met Thr Cys His Cys Gly Glu 
            100                 105                 110         


Glu Ala Met Lys Lys Tyr Ser Gln Ile Leu Ser His Phe Glu Lys Leu 
        115                 120                 125             


Glu Pro Gln Ala Ala Val Val Lys Ala Leu Gly Glu Leu Asp Ile Leu 
    130                 135                 140                 


Leu Gln Trp Met Glu Glu Thr Glu 
145                 150         


<210>  672
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  672

Val Pro Cys Val Ser Gly Gly Leu Pro Lys Pro Ala Asn Ile Thr Phe 
1               5                   10                  15      


Leu Ser Ile Asn Met Lys Asn Val Leu Gln Trp Thr Pro Pro Glu Gly 
            20                  25                  30          


Leu Gln Gly Val Lys Val Thr Tyr Thr Val Gln Tyr Phe Ile Tyr Gly 
        35                  40                  45              


Gln Lys Lys Trp Leu Asn Lys Ser Glu Cys Arg Asn Ile Asn Arg Thr 
    50                  55                  60                  


Tyr Cys Asp Leu Ser Ala Glu Thr Ser Asp Tyr Glu His Gln Tyr Tyr 
65                  70                  75                  80  


Ala Lys Val Lys Ala Ile Trp Gly Thr Lys Cys Ser Lys Trp Ala Glu 
                85                  90                  95      


Ser Gly Arg Phe Tyr Pro Phe Leu Glu Thr Gln Ile Gly Pro Pro Glu 
            100                 105                 110         


Val Ala Leu Thr Thr Asp Glu Lys Ser Ile Ser Val Val Leu Thr Ala 
        115                 120                 125             


Pro Glu Lys Trp Lys Arg Asn Pro Glu Asp Leu Pro Val Ser Met Gln 
    130                 135                 140                 


Gln Ile Tyr Ser Asn Leu Lys Tyr Asn Val Ser Val Leu Asn Thr Lys 
145                 150                 155                 160 


Ser Asn Arg Thr Trp Ser Gln Cys Val Thr Asn His Thr Leu Val Leu 
                165                 170                 175     


Thr Trp Leu Glu Pro Asn Thr Leu Tyr Cys Val His Val Glu Ser Phe 
            180                 185                 190         


Val Pro Gly Pro Pro Arg Arg Ala Gln Pro Ser Glu Lys Gln Cys Ala 
        195                 200                 205             


Arg Thr Leu Lys Asp Gln Ser Ser Glu Phe Lys Ala Lys 
    210                 215                 220     


<210>  673
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  673

Asp Glu Val Ala Ile Leu Pro Ala Pro Gln Asn Leu Ser Val Leu Ser 
1               5                   10                  15      


Thr Asn Met Lys His Leu Leu Met Trp Ser Pro Val Ile Ala Pro Gly 
            20                  25                  30          


Glu Thr Val Tyr Tyr Ser Val Glu Tyr Gln Gly Glu Tyr Glu Ser Leu 
        35                  40                  45              


Tyr Thr Ser His Ile Trp Ile Pro Ser Ser Trp Cys Ser Leu Thr Glu 
    50                  55                  60                  


Gly Pro Glu Cys Asp Val Thr Asp Asp Ile Thr Ala Thr Val Pro Tyr 
65                  70                  75                  80  


Asn Leu Arg Val Arg Ala Thr Leu Gly Ser Gln Thr Ser Ala Trp Ser 
                85                  90                  95      


Ile Leu Lys His Pro Phe Asn Arg Asn Ser Thr Ile Leu Thr Arg Pro 
            100                 105                 110         


Gly Met Glu Ile Thr Lys Asp Gly Phe His Leu Val Ile Glu Leu Glu 
        115                 120                 125             


Asp Leu Gly Pro Gln Phe Glu Phe Leu Val Ala Tyr Trp Arg Arg Glu 
    130                 135                 140                 


Pro Gly Ala Glu Glu His Val Lys Met Val Arg Ser Gly Gly Ile Pro 
145                 150                 155                 160 


Val His Leu Glu Thr Met Glu Pro Gly Ala Ala Tyr Cys Val Lys Ala 
                165                 170                 175     


Gln Thr Phe Val Lys Ala Ile Gly Arg Tyr Ser Ala Phe Ser Gln Thr 
            180                 185                 190         


Glu Cys Val Glu Val Gln Gly Glu Ala Ile Pro Leu 
        195                 200                 


<210>  674
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  674

Gln Gly Gln Asp Arg His Met Ile Arg Met Arg Gln Leu Ile Asp Ile 
1               5                   10                  15      


Val Asp Gln Leu Lys Asn Tyr Val Asn Asp Leu Val Pro Glu Phe Leu 
            20                  25                  30          


Pro Ala Pro Glu Asp Val Glu Thr Asn Cys Glu Trp Ser Ala Phe Ser 
        35                  40                  45              


Cys Phe Gln Lys Ala Gln Leu Lys Ser Ala Asn Thr Gly Asn Asn Glu 
    50                  55                  60                  


Arg Ile Ile Asn Val Ser Ile Lys Lys Leu Lys Arg Lys Pro Pro Ser 
65                  70                  75                  80  


Thr Asn Ala Gly Arg Arg Gln Lys His Arg Leu Thr Cys Pro Ser Cys 
                85                  90                  95      


Asp Ser Tyr Glu Lys Lys Pro Pro Lys Glu Phe Leu Glu Arg Phe Lys 
            100                 105                 110         


Ser Leu Leu Gln Lys Met Ile His Gln His Leu Ser Ser Arg Thr His 
        115                 120                 125             


Gly Ser Glu Asp Ser 
    130             


<210>  675
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  675

Cys Pro Asp Leu Val Cys Tyr Thr Asp Tyr Leu Gln Thr Val Ile Cys 
1               5                   10                  15      


Ile Leu Glu Met Trp Asn Leu His Pro Ser Thr Leu Thr Leu Thr Trp 
            20                  25                  30          


Gln Asp Gln Tyr Glu Glu Leu Lys Asp Glu Ala Thr Ser Cys Ser Leu 
        35                  40                  45              


His Arg Ser Ala His Asn Ala Thr His Ala Thr Tyr Thr Cys His Met 
    50                  55                  60                  


Asp Val Phe His Phe Met Ala Asp Asp Ile Phe Ser Val Asn Ile Thr 
65                  70                  75                  80  


Asp Gln Ser Gly Asn Tyr Ser Gln Glu Cys Gly Ser Phe Leu Leu Ala 
                85                  90                  95      


Glu Ser Ile Lys Pro Ala Pro Pro Phe Asn Val Thr Val Thr Phe Ser 
            100                 105                 110         


Gly Gln Tyr Asn Ile Ser Trp Arg Ser Asp Tyr Glu Asp Pro Ala Phe 
        115                 120                 125             


Tyr Met Leu Lys Gly Lys Leu Gln Tyr Glu Leu Gln Tyr Arg Asn Arg 
    130                 135                 140                 


Gly Asp Pro Trp Ala Val Ser Pro Arg Arg Lys Leu Ile Ser Val Asp 
145                 150                 155                 160 


Ser Arg Ser Val Ser Leu Leu Pro Leu Glu Phe Arg Lys Asp Ser Ser 
                165                 170                 175     


Tyr Glu Leu Gln Val Arg Ala Gly Pro Met Pro Gly Ser Ser Tyr Gln 
            180                 185                 190         


Gly Thr Trp Ser Glu Trp Ser Asp Pro Val Ile Phe Gln Thr Gln Ser 
        195                 200                 205             


Glu Glu Leu Lys Glu 
    210             


<210>  676
<211>  146
<212>  PRT
<213>  Homo Sapiens

<400>  676

Ala Pro Ile Ser Ser His Cys Arg Leu Asp Lys Ser Asn Phe Gln Gln 
1               5                   10                  15      


Pro Tyr Ile Thr Asn Arg Thr Phe Met Leu Ala Lys Glu Ala Ser Leu 
            20                  25                  30          


Ala Asp Asn Asn Thr Asp Val Arg Leu Ile Gly Glu Lys Leu Phe His 
        35                  40                  45              


Gly Val Ser Met Ser Glu Arg Cys Tyr Leu Met Lys Gln Val Leu Asn 
    50                  55                  60                  


Phe Thr Leu Glu Glu Val Leu Phe Pro Gln Ser Asp Arg Phe Gln Pro 
65                  70                  75                  80  


Tyr Met Gln Glu Val Val Pro Phe Leu Ala Arg Leu Ser Asn Arg Leu 
                85                  90                  95      


Ser Thr Cys His Ile Glu Gly Asp Asp Leu His Ile Gln Arg Asn Val 
            100                 105                 110         


Gln Lys Leu Lys Asp Thr Val Lys Lys Leu Gly Glu Ser Gly Glu Ile 
        115                 120                 125             


Lys Ala Ile Gly Glu Leu Asp Leu Leu Phe Met Ser Leu Arg Asn Ala 
    130                 135                 140                 


Cys Ile 
145     


<210>  677
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  677

His Ala Pro Glu Asp Pro Ser Asp Leu Leu Gln His Val Lys Phe Gln 
1               5                   10                  15      


Ser Ser Asn Phe Glu Asn Ile Leu Thr Trp Asp Ser Gly Pro Glu Gly 
            20                  25                  30          


Thr Pro Asp Thr Val Tyr Ser Ile Glu Tyr Lys Thr Tyr Gly Glu Arg 
        35                  40                  45              


Asp Trp Val Ala Lys Lys Gly Cys Gln Arg Ile Thr Arg Lys Ser Cys 
    50                  55                  60                  


Asn Leu Thr Val Glu Thr Gly Asn Leu Thr Glu Leu Tyr Tyr Ala Arg 
65                  70                  75                  80  


Val Thr Ala Val Ser Ala Gly Gly Arg Ser Ala Thr Lys Met Thr Asp 
                85                  90                  95      


Arg Phe Ser Ser Leu Gln His Thr Thr Leu Lys Pro Pro Asp Val Thr 
            100                 105                 110         


Cys Ile Ser Lys Val Arg Ser Ile Gln Met Ile Val His Pro Thr Pro 
        115                 120                 125             


Thr Pro Ile Arg Ala Gly Asp Gly His Arg Leu Thr Leu Glu Asp Ile 
    130                 135                 140                 


Phe His Asp Leu Phe Tyr His Leu Glu Leu Gln Val Asn Arg Thr Tyr 
145                 150                 155                 160 


Gln Met His Leu Gly Gly Lys Gln Arg Glu Tyr Glu Phe Phe Gly Leu 
                165                 170                 175     


Thr Pro Asp Thr Glu Phe Leu Gly Thr Ile Met Ile Cys Val Pro Thr 
            180                 185                 190         


Trp Ala Lys Glu Ser Ala Pro Tyr Met Cys Arg Val Lys Thr Leu Pro 
        195                 200                 205             


Asp Arg Thr Trp Thr 
    210             


<210>  678
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  678

Thr Gln Ser Thr His Glu Ser Leu Lys Pro Gln Arg Val Gln Phe Gln 
1               5                   10                  15      


Ser Arg Asn Phe His Asn Ile Leu Gln Trp Gln Pro Gly Arg Ala Leu 
            20                  25                  30          


Thr Gly Asn Ser Ser Val Tyr Phe Val Gln Tyr Lys Ile Tyr Gly Gln 
        35                  40                  45              


Arg Gln Trp Lys Asn Lys Glu Asp Cys Trp Gly Thr Gln Glu Leu Ser 
    50                  55                  60                  


Cys Asp Leu Thr Ser Glu Thr Ser Asp Ile Gln Glu Pro Tyr Tyr Gly 
65                  70                  75                  80  


Arg Val Arg Ala Ala Ser Ala Gly Ser Tyr Ser Glu Trp Ser Met Thr 
                85                  90                  95      


Pro Arg Phe Thr Pro Trp Trp Glu Thr Lys Ile Asp Pro Pro Val Met 
            100                 105                 110         


Asn Ile Thr Gln Val Asn Gly Ser Leu Leu Val Ile Leu His Ala Pro 
        115                 120                 125             


Asn Leu Pro Tyr Arg Tyr Gln Lys Glu Lys Asn Val Ser Ile Glu Asp 
    130                 135                 140                 


Tyr Tyr Glu Leu Leu Tyr Arg Val Phe Ile Ile Asn Asn Ser Leu Glu 
145                 150                 155                 160 


Lys Glu Gln Lys Val Tyr Glu Gly Ala His Arg Ala Val Glu Ile Glu 
                165                 170                 175     


Ala Leu Thr Pro His Ser Ser Tyr Cys Val Val Ala Glu Ile Tyr Gln 
            180                 185                 190         


Pro Met Leu Asp Arg Arg Ser Gln Arg Ser Glu Glu Arg Cys Val Glu 
        195                 200                 205             


Ile Pro 
    210 


<210>  679
<211>  170
<212>  PRT
<213>  Homo Sapiens

<400>  679

Arg Ala Val Pro Gly Gly Ser Ser Pro Ala Trp Thr Gln Cys Gln Gln 
1               5                   10                  15      


Leu Ser Gln Lys Leu Cys Thr Leu Ala Trp Ser Ala His Pro Leu Val 
            20                  25                  30          


Gly His Met Asp Leu Arg Glu Glu Gly Asp Glu Glu Thr Thr Asn Asp 
        35                  40                  45              


Val Pro His Ile Gln Cys Gly Asp Gly Cys Asp Pro Gln Gly Leu Arg 
    50                  55                  60                  


Asp Asn Ser Gln Phe Cys Leu Gln Arg Ile His Gln Gly Leu Ile Phe 
65                  70                  75                  80  


Tyr Glu Lys Leu Leu Gly Ser Asp Ile Phe Thr Gly Glu Pro Ser Leu 
                85                  90                  95      


Leu Pro Asp Ser Pro Val Gly Gln Leu His Ala Ser Leu Leu Gly Leu 
            100                 105                 110         


Ser Gln Leu Leu Gln Pro Glu Gly His His Trp Glu Thr Gln Gln Ile 
        115                 120                 125             


Pro Ser Leu Ser Pro Ser Gln Pro Trp Gln Arg Leu Leu Leu Arg Phe 
    130                 135                 140                 


Lys Ile Leu Arg Ser Leu Gln Ala Phe Val Ala Val Ala Ala Arg Val 
145                 150                 155                 160 


Phe Ala His Gly Ala Ala Thr Leu Ser Pro 
                165                 170 


<210>  680
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  680

Gly Ile Thr Asn Ile Asn Cys Ser Gly His Ile Trp Val Glu Pro Ala 
1               5                   10                  15      


Thr Ile Phe Lys Met Gly Met Asn Ile Ser Ile Tyr Cys Gln Ala Ala 
            20                  25                  30          


Ile Lys Asn Cys Gln Pro Arg Lys Leu His Phe Tyr Lys Asn Gly Ile 
        35                  40                  45              


Lys Glu Arg Phe Gln Ile Thr Arg Ile Asn Lys Thr Thr Ala Arg Leu 
    50                  55                  60                  


Trp Tyr Lys Asn Phe Leu Glu Pro His Ala Ser Met Tyr Cys Thr Ala 
65                  70                  75                  80  


Glu Cys Pro Lys His Phe Gln Glu Thr Leu Ile Cys Gly Lys Asp Ile 
                85                  90                  95      


Ser Ser Gly Tyr Pro Pro Asp Ile Pro Asp Glu Val Thr Cys Val Ile 
            100                 105                 110         


Tyr Glu Tyr Ser Gly Asn Met Thr Cys Thr Trp Asn Ala Gly Lys Leu 
        115                 120                 125             


Thr Tyr Ile Asp Thr Lys Tyr Val Val His Val Lys Ser Leu Glu Thr 
    130                 135                 140                 


Glu Glu Glu Gln Gln Tyr Leu Thr Ser Ser Tyr Ile Asn Ile Ser Thr 
145                 150                 155                 160 


Asp Ser Leu Gln Gly Gly Lys Lys Tyr Leu Val Trp Val Gln Ala Ala 
                165                 170                 175     


Asn Ala Leu Gly Met Glu Glu Ser Lys Gln Leu Gln Ile His Leu Asp 
            180                 185                 190         


Asp Ile Val Ile Pro Ser Ala Ala Val Ile Ser Arg Ala Glu Thr Ile 
        195                 200                 205             


Asn Ala Thr Val Pro Lys Thr Ile Ile Tyr Trp Asp Ser Gln Thr Thr 
    210                 215                 220                 


Ile Glu Lys Val Ser Cys Glu Met Arg Tyr Lys Ala Thr Thr Asn Gln 
225                 230                 235                 240 


Thr Trp Asn Val Lys Glu Phe Asp Thr Asn Phe Thr Tyr Val Gln Gln 
                245                 250                 255     


Ser Glu Phe Tyr Leu Glu Pro Asn Ile Lys Tyr Val Phe Gln Val Arg 
            260                 265                 270         


Cys Gln Glu Thr Gly Lys Arg Tyr Trp Gln Pro Trp Ser Ser Leu Phe 
        275                 280                 285             


Phe His Lys Thr Pro Glu Thr Val Pro Gln Val Thr Ser Lys Ala Phe 
    290                 295                 300                 


Gln His Asp Thr Trp Asn Ser Gly Leu Thr Val Ala Ser Ile Ser Thr 
305                 310                 315                 320 


Gly His Leu Thr Ser Asp Asn Arg Gly Asp Ile Gly 
                325                 330         


<210>  681
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  681

Gln Glu Phe His Phe Gly Pro Cys Gln Val Lys Gly Val Val Pro Gln 
1               5                   10                  15      


Lys Leu Trp Glu Ala Phe Trp Ala Val Lys Asp Thr Met Gln Ala Gln 
            20                  25                  30          


Asp Asn Ile Thr Ser Ala Arg Leu Leu Gln Gln Glu Val Leu Gln Asn 
        35                  40                  45              


Val Ser Asp Ala Glu Ser Cys Tyr Leu Val His Thr Leu Leu Glu Phe 
    50                  55                  60                  


Tyr Leu Lys Thr Val Phe Lys Asn Tyr His Asn Arg Thr Val Glu Val 
65                  70                  75                  80  


Arg Thr Leu Lys Ser Phe Ser Thr Leu Ala Asn Asn Phe Val Leu Ile 
                85                  90                  95      


Val Ser Gln Leu Gln Pro Ser Gln Glu Asn Glu Met Phe Ser Ile Arg 
            100                 105                 110         


Asp Ser Ala His Arg Arg Phe Leu Leu Phe Arg Arg Ala Phe Lys Gln 
        115                 120                 125             


Leu Asp Val Glu Ala Ala Leu Thr Lys Ala Leu Gly Glu Val Asp Ile 
    130                 135                 140                 


Leu Leu Thr Trp Met Gln Lys Phe Tyr Lys Leu 
145                 150                 155 


<210>  682
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  682

Tyr Ser His Trp Pro Ser Cys Cys Pro Ser Lys Gly Gln Asp Thr Ser 
1               5                   10                  15      


Glu Glu Leu Leu Arg Trp Ser Thr Val Pro Val Pro Pro Leu Glu Pro 
            20                  25                  30          


Ala Arg Pro Asn Arg His Pro Glu Ser Cys Arg Ala Ser Glu Asp Gly 
        35                  40                  45              


Pro Leu Asn Ser Arg Ala Ile Ser Pro Trp Arg Tyr Glu Leu Asp Arg 
    50                  55                  60                  


Asp Leu Asn Arg Leu Pro Gln Asp Leu Tyr His Ala Arg Cys Leu Cys 
65                  70                  75                  80  


Pro His Cys Val Ser Leu Gln Thr Gly Ser His Met Asp Pro Arg Gly 
                85                  90                  95      


Asn Ser Glu Leu Leu Tyr His Asn Gln Thr Val Phe Tyr Arg Arg Pro 
            100                 105                 110         


Cys His Gly Glu Lys Gly Thr His Lys Gly Tyr Cys Leu Glu Arg Arg 
        115                 120                 125             


Leu Tyr Arg Val Ser Leu Ala Cys Val Cys Val Arg Pro Arg Val Met 
    130                 135                 140                 


Gly 
145 


<210>  683
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  683

Lys His Lys Gln Ser Ser Phe Thr Lys Ser Cys Tyr Pro Arg Gly Thr 
1               5                   10                  15      


Leu Ser Gln Ala Val Asp Ala Leu Tyr Ile Lys Ala Ala Trp Leu Lys 
            20                  25                  30          


Ala Thr Ile Pro Glu Asp Arg Ile Lys Asn Ile Arg Leu Leu Lys Lys 
        35                  40                  45              


Lys Thr Lys Lys Gln Phe Met Lys Asn Cys Gln Phe Gln Glu Gln Leu 
    50                  55                  60                  


Leu Ser Phe Phe Met Glu Asp Val Phe Gly Gln Leu Gln Leu Gln Gly 
65                  70                  75                  80  


Cys Lys Lys Ile Arg Phe Val Glu Asp Phe His Ser Leu Arg Gln Lys 
                85                  90                  95      


Leu Ser His Cys Ile Ser Cys Ala Ser Ser Ala Arg Glu Met Lys Ser 
            100                 105                 110         


Ile Thr Arg Met Lys Arg Ile Phe Tyr Arg Ile Gly Asn Lys Gly Ile 
        115                 120                 125             


Tyr Lys Ala Ile Ser Glu Leu Asp Ile Leu Leu Ser Trp Ile Lys Lys 
    130                 135                 140                 


Leu Leu Glu Ser Ser Gln 
145                 150 


<210>  684
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  684

Phe Pro Arg Pro Pro Gly Arg Pro Gln Leu Ser Leu Gln Glu Leu Arg 
1               5                   10                  15      


Arg Glu Phe Thr Val Ser Leu His Leu Ala Arg Lys Leu Leu Ala Glu 
            20                  25                  30          


Val Arg Gly Gln Ala His Arg Phe Ala Glu Ser His Leu Pro Gly Val 
        35                  40                  45              


Asn Leu Tyr Leu Leu Pro Leu Gly Glu Gln Leu Pro Asp Val Ser Leu 
    50                  55                  60                  


Thr Phe Gln Ala Trp Arg Arg Leu Ser Asp Pro Glu Arg Leu Cys Phe 
65                  70                  75                  80  


Ile Ser Thr Thr Leu Gln Pro Phe His Ala Leu Leu Gly Gly Leu Gly 
                85                  90                  95      


Thr Gln Gly Arg Trp Thr Asn Met Glu Arg Met Gln Leu Trp Ala Met 
            100                 105                 110         


Arg Leu Asp Leu Arg Asp Leu Gln Arg His Leu Arg Phe Gln Val Leu 
        115                 120                 125             


Ala Ala Gly Phe Asn Leu Pro Glu Glu Glu Glu Glu Glu Glu Glu Glu 
    130                 135                 140                 


Glu Glu Glu Glu Arg Lys Gly Leu Leu Pro Gly Ala Leu Gly Ser Ala 
145                 150                 155                 160 


Leu Gln Gly Pro Ala Gln Val Ser Trp Pro Gln Leu Leu Ser Thr Tyr 
                165                 170                 175     


Arg Leu Leu His Ser Leu Glu Leu Val Leu Ser Arg Ala Val Arg Glu 
            180                 185                 190         


Leu Leu Leu Leu Ser Lys Ala Gly His Ser Val Trp Pro Leu Gly Phe 
        195                 200                 205             


Pro Thr Leu Ser Pro Gln Pro 
    210                 215 


<210>  685
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  685

Gln Gly Ser Ala Gly Pro Leu Gln Cys Tyr Gly Val Gly Pro Leu Gly 
1               5                   10                  15      


Asp Leu Asn Cys Ser Trp Glu Pro Leu Gly Asp Leu Gly Ala Pro Ser 
            20                  25                  30          


Glu Leu His Leu Gln Ser Gln Lys Tyr Arg Ser Asn Lys Thr Gln Thr 
        35                  40                  45              


Val Ala Val Ala Ala Gly Arg Ser Trp Val Ala Ile Pro Arg Glu Gln 
    50                  55                  60                  


Leu Thr Met Ser Asp Lys Leu Leu Val Trp Gly Thr Lys Ala Gly Gln 
65                  70                  75                  80  


Pro Leu Trp Pro Pro Val Phe Val Asn Leu Glu Thr Gln Met Lys Pro 
                85                  90                  95      


Asn Ala Pro Arg Leu Gly Pro Asp Val Asp Phe Ser Glu Asp Asp Pro 
            100                 105                 110         


Leu Glu Ala Thr Val His Trp Ala Pro Pro Thr Trp Pro Ser His Lys 
        115                 120                 125             


Val Leu Ile Cys Gln Phe His Tyr Arg Arg Cys Gln Glu Ala Ala Trp 
    130                 135                 140                 


Thr Leu Leu Glu Pro Glu Leu Lys Thr Ile Pro Leu Thr Pro Val Glu 
145                 150                 155                 160 


Ile Gln Asp Leu Glu Leu Ala Thr Gly Tyr Lys Val Tyr Gly Arg Cys 
                165                 170                 175     


Arg Met Glu Lys Glu Glu Asp Leu Trp Gly Glu Trp Ser Pro Ile Leu 
            180                 185                 190         


Ser Phe Gln Thr Pro Pro Ser Ala Pro Lys Asp Val Trp Val Ser Gly 
        195                 200                 205             


Asn Leu Cys Gly Thr Pro Gly Gly Glu Glu Pro Leu Leu Leu Trp Lys 
    210                 215                 220                 


Ala Pro Gly Pro Cys Val Gln Val Ser Tyr Lys Val Trp Phe Trp Val 
225                 230                 235                 240 


Gly Gly Arg Glu Leu Ser Pro Glu Gly Ile Thr Cys Cys Cys Ser Leu 
                245                 250                 255     


Ile Pro Ser Gly Ala Glu Trp Ala Arg Val Ser Ala Val Asn Ala Thr 
            260                 265                 270         


Ser Trp Glu Pro Leu Thr Asn Leu Ser Leu Val Cys Leu Asp Ser Ala 
        275                 280                 285             


Ser Ala Pro Arg Ser Val Ala Val Ser Ser Ile Ala Gly Ser Thr Glu 
    290                 295                 300                 


Leu Leu Val Thr Trp Gln Pro Gly Pro Gly Glu Pro Leu Glu His Val 
305                 310                 315                 320 


Val Asp Trp Ala Arg Asp Gly Asp Pro Leu Glu Lys Leu Asn Trp Val 
                325                 330                 335     


Arg Leu Pro Pro Gly Asn Leu Ser Ala Leu Leu Pro Gly Asn Phe Thr 
            340                 345                 350         


Val Gly Val Pro Tyr Arg Ile Thr Val Thr Ala Val Ser Ala Ser Gly 
        355                 360                 365             


Leu Ala Ser Ala Ser Ser Val Trp Gly Phe Arg Glu Glu Leu Ala Pro 
    370                 375                 380                 


Leu Val Gly Pro Thr Leu Trp Arg Leu Gln Asp Ala Pro Pro Gly Thr 
385                 390                 395                 400 


Pro Ala Ile Ala Trp Gly Glu Val Pro Arg His Gln Leu Arg Gly His 
                405                 410                 415     


Leu Thr His Tyr Thr Leu Cys Ala Gln Ser Gly Thr Ser Pro Ser Val 
            420                 425                 430         


Cys Met Asn Val Ser Gly Asn Thr Gln Ser Val Thr Leu Pro Asp Leu 
        435                 440                 445             


Pro Trp Gly Pro Cys Glu Leu Trp Val Thr Ala Ser Thr Ile Ala Gly 
    450                 455                 460                 


Gln Gly Pro Pro Gly Pro Ile Leu Arg Leu His Leu Pro Asp Asn Thr 
465                 470                 475                 480 


Leu Arg Trp Lys 
                


<210>  686
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  686

Val Pro Val Ala Arg Leu Arg Gly Ala Leu Pro Asp Ala Arg Gly Cys 
1               5                   10                  15      


His Ile Ala Gln Phe Lys Ser Leu Ser Pro Gln Glu Leu Gln Ala Phe 
            20                  25                  30          


Lys Arg Ala Lys Asp Ala Leu Glu Glu Ser Leu Leu Leu Lys Asp Cys 
        35                  40                  45              


Lys Cys Arg Ser Arg Leu Phe Pro Arg Thr Trp Asp Leu Arg Gln Leu 
    50                  55                  60                  


Gln Val Arg Glu Arg Pro Val Ala Leu Glu Ala Glu Leu Ala Leu Thr 
65                  70                  75                  80  


Leu Lys Val Leu Glu Ala Thr Ala Asp Thr Asp Pro Ala Leu Gly Asp 
                85                  90                  95      


Val Leu Asp Gln Pro Leu His Thr Leu His His Ile Leu Ser Gln Leu 
            100                 105                 110         


Arg Ala Cys Ile Gln Pro Gln Pro Thr Ala Gly Pro Arg Thr Arg Gly 
        115                 120                 125             


Arg Leu His His Trp Leu His Arg Leu Gln Glu Ala Pro Lys Lys Glu 
    130                 135                 140                 


Ser Pro Gly Cys Leu Glu Ala Ser Val Thr Phe Asn Leu Phe Arg Leu 
145                 150                 155                 160 


Leu Thr Arg Asp Leu Asn Cys Val Ala Ser Gly Asp Leu Cys Val 
                165                 170                 175 


<210>  687
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  687

Arg Pro Arg Leu Ala Pro Pro Gln Asn Val Thr Leu Leu Ser Gln Asn 
1               5                   10                  15      


Phe Ser Val Tyr Leu Thr Trp Leu Pro Gly Leu Gly Asn Pro Gln Asp 
            20                  25                  30          


Val Thr Tyr Phe Val Ala Tyr Gln Ser Ser Pro Thr Arg Arg Arg Trp 
        35                  40                  45              


Arg Glu Val Glu Glu Cys Ala Gly Thr Lys Glu Leu Leu Cys Ser Met 
    50                  55                  60                  


Met Cys Leu Lys Lys Gln Asp Leu Tyr Asn Lys Phe Lys Gly Arg Val 
65                  70                  75                  80  


Arg Thr Val Ser Pro Ser Ser Lys Ser Pro Trp Val Glu Ser Glu Tyr 
                85                  90                  95      


Leu Asp Tyr Leu Phe Glu Val Glu Pro Ala Pro Pro Val Leu Val Leu 
            100                 105                 110         


Thr Gln Thr Glu Glu Ile Leu Ser Ala Asn Ala Thr Tyr Gln Leu Pro 
        115                 120                 125             


Pro Cys Met Pro Pro Leu Asp Leu Lys Tyr Glu Val Ala Phe Trp Lys 
    130                 135                 140                 


Glu Gly Ala Gly Asn Lys Thr Leu Phe Pro Val Thr Pro His Gly Gln 
145                 150                 155                 160 


Pro Val Gln Ile Thr Leu Gln Pro Ala Ala Ser Glu His His Cys Leu 
                165                 170                 175     


Ser Ala Arg Thr Ile Tyr Thr Phe Ser Val Pro Lys Tyr Ser Lys Phe 
            180                 185                 190         


Ser Lys Pro Thr Cys Phe Leu Leu Glu Val Pro Glu Ala Asn Trp Ala 
        195                 200                 205             


<210>  688
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  688

Gly Pro Val Pro Thr Ser Lys Pro Thr Thr Thr Gly Lys Gly Cys His 
1               5                   10                  15      


Ile Gly Arg Phe Lys Ser Leu Ser Pro Gln Glu Leu Ala Ser Phe Lys 
            20                  25                  30          


Lys Ala Arg Asp Ala Leu Glu Glu Ser Leu Lys Leu Lys Asn Trp Ser 
        35                  40                  45              


Cys Ser Ser Pro Val Phe Pro Gly Asn Trp Asp Leu Arg Leu Leu Gln 
    50                  55                  60                  


Val Arg Glu Arg Pro Val Ala Leu Glu Ala Glu Leu Ala Leu Thr Leu 
65                  70                  75                  80  


Lys Val Leu Glu Ala Ala Ala Gly Pro Ala Leu Glu Asp Val Leu Asp 
                85                  90                  95      


Gln Pro Leu His Thr Leu His His Ile Leu Ser Gln Leu Gln Ala Cys 
            100                 105                 110         


Ile Gln Pro Gln Pro Thr Ala Gly Pro Arg Pro Arg Gly Arg Leu His 
        115                 120                 125             


His Trp Leu His Arg Leu Gln Glu Ala Pro Lys Lys Glu Ser Ala Gly 
    130                 135                 140                 


Cys Leu Glu Ala Ser Val Thr Phe Asn Leu Phe Arg Leu Leu Thr Arg 
145                 150                 155                 160 


Asp Leu Lys Tyr Val Ala Asp Gly Asn Leu Cys Leu Arg Thr Ser Thr 
                165                 170                 175     


His Pro Glu Ser Thr 
            180     


<210>  689
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  689

Glu Leu Cys Asp Asp Asp Pro Pro Glu Ile Pro His Ala Thr Phe Lys 
1               5                   10                  15      


Ala Met Ala Tyr Lys Glu Gly Thr Met Leu Asn Cys Glu Cys Lys Arg 
            20                  25                  30          


Gly Phe Arg Arg Ile Lys Ser Gly Ser Leu Tyr Met Leu Cys Thr Gly 
        35                  40                  45              


Asn Ser Ser His Ser Ser Trp Asp Asn Gln Cys Gln Cys Thr Ser Ser 
    50                  55                  60                  


Ala Thr Arg Asn Thr Thr Lys Gln Val Thr Pro Gln Pro Glu Glu Gln 
65                  70                  75                  80  


Lys Glu Arg Lys Thr Thr Glu Met Gln Ser Pro Met Gln Pro Val Asp 
                85                  90                  95      


Gln Ala Ser Leu Pro Gly His Cys Arg Glu Pro Pro Pro Trp Glu Asn 
            100                 105                 110         


Glu Ala Thr Glu Arg Ile Tyr His Phe Val Val Gly Gln Met Val Tyr 
        115                 120                 125             


Tyr Gln Cys Val Gln Gly Tyr Arg Ala Leu His Arg Gly Pro Ala Glu 
    130                 135                 140                 


Ser Val Cys Lys Met Thr His Gly Lys Thr Arg Trp Thr Gln Pro Gln 
145                 150                 155                 160 


Leu Ile Cys Thr Gly Glu Met Glu Thr Ser Gln Phe Pro Gly Glu Glu 
                165                 170                 175     


Lys Pro Gln Ala Ser Pro Glu Gly Arg Pro Glu Ser Glu Thr Ser Cys 
            180                 185                 190         


Leu Val Thr Thr Thr Asp Phe Gln Ile Gln Thr Glu Met Ala Ala Thr 
        195                 200                 205             


Met Glu Thr Ser Ile Phe Thr Thr Glu Tyr Gln 
    210                 215                 


<210>  690
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  690

Ala Val Asn Gly Thr Ser Gln Phe Thr Cys Phe Tyr Asn Ser Arg Ala 
1               5                   10                  15      


Asn Ile Ser Cys Val Trp Ser Gln Asp Gly Ala Leu Gln Asp Thr Ser 
            20                  25                  30          


Cys Gln Val His Ala Trp Pro Asp Arg Arg Arg Trp Asn Gln Thr Cys 
        35                  40                  45              


Glu Leu Leu Pro Val Ser Gln Ala Ser Trp Ala Cys Asn Leu Ile Leu 
    50                  55                  60                  


Gly Ala Pro Asp Ser Gln Lys Leu Thr Thr Val Asp Ile Val Thr Leu 
65                  70                  75                  80  


Arg Val Leu Cys Arg Glu Gly Val Arg Trp Arg Val Met Ala Ile Gln 
                85                  90                  95      


Asp Phe Lys Pro Phe Glu Asn Leu Arg Leu Met Ala Pro Ile Ser Leu 
            100                 105                 110         


Gln Val Val His Val Glu Thr His Arg Cys Asn Ile Ser Trp Glu Ile 
        115                 120                 125             


Ser Gln Ala Ser His Tyr Phe Glu Arg His Leu Glu Phe Glu Ala Arg 
    130                 135                 140                 


Thr Leu Ser Pro Gly His Thr Trp Glu Glu Ala Pro Leu Leu Thr Leu 
145                 150                 155                 160 


Lys Gln Lys Gln Glu Trp Ile Cys Leu Glu Thr Leu Thr Pro Asp Thr 
                165                 170                 175     


Gln Tyr Glu Phe Gln Val Arg Val Lys Pro Leu Gln Gly Glu Phe Thr 
            180                 185                 190         


Thr Trp Ser Pro Trp Ser Gln Pro Leu Ala Phe Arg Thr Lys Pro Ala 
        195                 200                 205             


Ala Leu Gly Lys Asp Thr 
    210                 


<210>  691
<211>  240
<212>  PRT
<213>  Homo Sapiens

<400>  691

Leu Asn Thr Thr Ile Leu Thr Pro Asn Gly Asn Glu Asp Thr Thr Ala 
1               5                   10                  15      


Asp Phe Phe Leu Thr Thr Met Pro Thr Asp Ser Leu Ser Val Ser Thr 
            20                  25                  30          


Leu Pro Leu Pro Glu Val Gln Cys Phe Val Phe Asn Val Glu Tyr Met 
        35                  40                  45              


Asn Cys Thr Trp Asn Ser Ser Ser Glu Pro Gln Pro Thr Asn Leu Thr 
    50                  55                  60                  


Leu His Tyr Trp Tyr Lys Asn Ser Asp Asn Asp Lys Val Gln Lys Cys 
65                  70                  75                  80  


Ser His Tyr Leu Phe Ser Glu Glu Ile Thr Ser Gly Cys Gln Leu Gln 
                85                  90                  95      


Lys Lys Glu Ile His Leu Tyr Gln Thr Phe Val Val Gln Leu Gln Asp 
            100                 105                 110         


Pro Arg Glu Pro Arg Arg Gln Ala Thr Gln Met Leu Lys Leu Gln Asn 
        115                 120                 125             


Leu Val Ile Pro Trp Ala Pro Glu Asn Leu Thr Leu His Lys Leu Ser 
    130                 135                 140                 


Glu Ser Gln Leu Glu Leu Asn Trp Asn Asn Arg Phe Leu Asn His Cys 
145                 150                 155                 160 


Leu Glu His Leu Val Gln Tyr Arg Thr Asp Trp Asp His Ser Trp Thr 
                165                 170                 175     


Glu Gln Ser Val Asp Tyr Arg His Lys Phe Ser Leu Pro Ser Val Asp 
            180                 185                 190         


Gly Gln Lys Arg Tyr Thr Phe Arg Val Arg Ser Arg Phe Asn Pro Leu 
        195                 200                 205             


Cys Gly Ser Ala Gln His Trp Ser Glu Trp Ser His Pro Ile His Trp 
    210                 215                 220                 


Gly Ser Asn Thr Ser Lys Glu Asn Pro Phe Leu Phe Ala Leu Glu Ala 
225                 230                 235                 240 


<210>  692
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  692

Ala Pro Met Thr Gln Thr Thr Pro Leu Lys Thr Ser Trp Val Asn Cys 
1               5                   10                  15      


Ser Asn Met Ile Asp Glu Ile Ile Thr His Leu Lys Gln Pro Pro Leu 
            20                  25                  30          


Pro Leu Leu Asp Phe Asn Asn Leu Asn Gly Glu Asp Gln Asp Ile Leu 
        35                  40                  45              


Met Glu Asn Asn Leu Arg Arg Pro Asn Leu Glu Ala Phe Asn Arg Ala 
    50                  55                  60                  


Val Lys Ser Leu Gln Asn Ala Ser Ala Ile Glu Ser Ile Leu Lys Asn 
65                  70                  75                  80  


Leu Leu Pro Cys Leu Pro Leu Ala Thr Ala Ala Pro Thr Arg His Pro 
                85                  90                  95      


Ile His Ile Lys Asp Gly Asp Trp Asn Glu Phe Arg Arg Lys Leu Thr 
            100                 105                 110         


Phe Tyr Leu Lys Thr Leu Glu Asn Ala Gln Ala Gln Gln Thr Thr Leu 
        115                 120                 125             


Ser Leu Ala Ile Phe 
    130             


<210>  693
<211>  141
<212>  PRT
<213>  Homo Sapiens

<400>  693

Ser His Thr Leu Pro Val Arg Leu Leu Arg Pro Ser Asp Asp Val Gln 
1               5                   10                  15      


Lys Ile Val Glu Glu Leu Gln Ser Leu Ser Lys Met Leu Leu Lys Asp 
            20                  25                  30          


Val Glu Glu Glu Lys Gly Val Leu Val Ser Gln Asn Tyr Thr Leu Pro 
        35                  40                  45              


Cys Leu Ser Pro Asp Ala Gln Pro Pro Asn Asn Ile His Ser Pro Ala 
    50                  55                  60                  


Ile Arg Ala Tyr Leu Lys Thr Ile Arg Gln Leu Asp Asn Lys Ser Val 
65                  70                  75                  80  


Ile Asp Glu Ile Ile Glu His Leu Asp Lys Leu Ile Phe Gln Asp Ala 
                85                  90                  95      


Pro Glu Thr Asn Ile Ser Val Pro Thr Asp Thr His Glu Cys Lys Arg 
            100                 105                 110         


Phe Ile Leu Thr Ile Ser Gln Gln Phe Ser Glu Cys Met Asp Leu Ala 
        115                 120                 125             


Leu Lys Ser Leu Thr Ser Gly Ala Gln Gln Ala Thr Thr 
    130                 135                 140     


<210>  694
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  694

Ser Leu Pro Ala Lys Pro Glu Asn Ile Ser Cys Val Tyr Tyr Tyr Arg 
1               5                   10                  15      


Lys Asn Leu Thr Cys Thr Trp Ser Pro Gly Lys Glu Thr Ser Tyr Thr 
            20                  25                  30          


Gln Tyr Thr Val Lys Arg Thr Tyr Ala Phe Gly Glu Lys His Asp Asn 
        35                  40                  45              


Cys Thr Thr Asn Ser Ser Thr Ser Glu Asn Arg Ala Ser Cys Ser Phe 
    50                  55                  60                  


Phe Leu Pro Arg Ile Thr Ile Pro Asp Asn Tyr Thr Ile Glu Val Glu 
65                  70                  75                  80  


Ala Glu Asn Gly Asp Gly Val Ile Lys Ser His Met Thr Tyr Trp Arg 
                85                  90                  95      


Leu Glu Asn Ile Ala Lys Thr Glu Pro Pro Lys Ile Phe Arg Val Lys 
            100                 105                 110         


Pro Val Leu Gly Ile Lys Arg Met Ile Gln Ile Glu Trp Ile Lys Pro 
        115                 120                 125             


Glu Leu Ala Pro Val Ser Ser Asp Leu Lys Tyr Thr Leu Arg Phe Arg 
    130                 135                 140                 


Thr Val Asn Ser Thr Ser Trp Met Glu Val Asn Phe Ala Lys Asn Arg 
145                 150                 155                 160 


Lys Asp Lys Asn Gln Thr Tyr Asn Leu Thr Gly Leu Gln Pro Phe Thr 
                165                 170                 175     


Glu Tyr Val Ile Ala Leu Arg Cys Ala Val Lys Glu Ser Lys Phe Trp 
            180                 185                 190         


Ser Asp Trp Ser Gln Glu Lys Met Gly Met Thr Glu Glu Glu Ala Pro 
        195                 200                 205             


Cys Gly Leu Glu Leu Trp Arg Val Leu Lys Pro Ala Glu Ala Asp Gly 
    210                 215                 220                 


Arg Arg Pro Val Arg Leu Leu Trp Lys Lys Ala Arg Gly Ala Pro Val 
225                 230                 235                 240 


Leu Glu Lys Thr Leu Gly Tyr Asn Ile Trp Tyr Tyr Pro Glu Ser Asn 
                245                 250                 255     


Thr Asn Leu Thr Glu Thr Met Asn Thr Thr Asn Gln Gln Leu Glu Leu 
            260                 265                 270         


His Leu Gly Gly Glu Ser Phe Trp Val Ser Met Ile Ser Tyr Asn Ser 
        275                 280                 285             


Leu Gly Lys Ser Pro Val Ala Thr Leu Arg Ile Pro Ala Ile Gln Glu 
    290                 295                 300                 


Lys Ser Phe Gln Cys Ile Glu Val Met Gln Ala Cys Val Ala Glu Asp 
305                 310                 315                 320 


Gln Leu Val Val Lys Trp Gln Ser Ser Ala Leu Asp Val Asn Thr Trp 
                325                 330                 335     


Met Ile Glu Trp Phe Pro Asp Val Asp Ser Glu Pro Thr Thr Leu Ser 
            340                 345                 350         


Trp Glu Ser Val Ser Gln Ala Thr Asn Trp Thr Ile Gln Gln Asp Lys 
        355                 360                 365             


Leu Lys Pro Phe Trp Cys Tyr Asn Ile Ser Val Tyr Pro Met Leu His 
    370                 375                 380                 


Asp Lys Val Gly Glu Pro Tyr Ser Ile Gln Ala Tyr Ala Lys Glu Gly 
385                 390                 395                 400 


Val Pro Ser Glu Gly Pro Glu Thr Lys Val Glu Asn Ile Gly Val Lys 
                405                 410                 415     


Thr Val Thr Ile Thr Trp Lys Glu Ile Pro Lys Ser Glu Arg Lys Gly 
            420                 425                 430         


Ile Ile Cys Asn Tyr Thr Ile Phe Tyr Gln Ala Glu Gly Gly Lys Gly 
        435                 440                 445             


Phe Ser Lys Thr Val Asn Ser Ser Ile Leu Gln Tyr Gly Leu Glu Ser 
    450                 455                 460                 


Leu Lys Arg Lys Thr Ser Tyr Ile Val Gln Val Met Ala Ser Thr Ser 
465                 470                 475                 480 


Ala Gly Gly Thr Asn Gly Thr Ser Ile Asn Phe Lys Thr Leu Ser Phe 
                485                 490                 495     


Ser Val Phe Glu 
            500 


<210>  695
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  695

Ala Trp Val Ser Ala Cys Asp Thr Glu Asp Thr Val Gly His Leu Gly 
1               5                   10                  15      


Pro Trp Arg Asp Lys Asp Pro Ala Leu Trp Cys Gln Leu Cys Leu Ser 
            20                  25                  30          


Ser Gln His Gln Ala Ile Glu Arg Phe Tyr Asp Lys Met Gln Asn Ala 
        35                  40                  45              


Glu Ser Gly Arg Gly Gln Val Met Ser Ser Leu Ala Glu Leu Glu Asp 
    50                  55                  60                  


Asp Phe Lys Glu Gly Tyr Leu Glu Thr Val Ala Ala Tyr Tyr Glu Glu 
65                  70                  75                  80  


Gln His Pro Glu Leu Thr Pro Leu Leu Glu Lys Glu Arg Asp Gly Leu 
                85                  90                  95      


Arg Cys Arg Gly Asn Arg Ser Pro Val Pro Asp Val Glu Asp Pro Ala 
            100                 105                 110         


Thr Glu Glu Pro Gly Glu Ser Phe Cys Asp Lys Val Met Arg Trp Phe 
        115                 120                 125             


Gln Ala Met Leu Gln Arg Leu Gln Thr Trp Trp His Gly Val Leu Ala 
    130                 135                 140                 


Trp Val Lys Glu Lys Val Val Ala Leu Val His Ala Val Gln Ala Leu 
145                 150                 155                 160 


Trp Lys Gln Phe Gln Ser Phe Cys Cys Ser Leu Ser Glu Leu Phe Met 
                165                 170                 175     


Ser Ser Phe Gln Ser Tyr Gly Ala Pro Arg Gly Asp Lys Glu Glu Leu 
            180                 185                 190         


Thr Pro Gln Lys Cys Ser Glu Pro Gln Ser Ser Lys 
        195                 200                 


<210>  696
<211>  270
<212>  PRT
<213>  Homo Sapiens

<400>  696

Met Lys Pro Lys Met Lys Tyr Ser Thr Asn Lys Ile Ser Thr Ala Lys 
1               5                   10                  15      


Trp Lys Asn Thr Ala Ser Lys Ala Leu Cys Phe Lys Leu Gly Lys Ser 
            20                  25                  30          


Gln Gln Lys Ala Lys Glu Val Cys Pro Met Tyr Phe Met Lys Leu Arg 
        35                  40                  45              


Ser Gly Leu Met Ile Lys Lys Glu Ala Cys Tyr Phe Arg Arg Glu Thr 
    50                  55                  60                  


Thr Lys Arg Pro Ser Leu Lys Thr Gly Arg Lys His Lys Arg His Leu 
65                  70                  75                  80  


Val Leu Ala Ala Cys Gln Gln Gln Ser Thr Val Glu Cys Phe Ala Phe 
                85                  90                  95      


Gly Ile Ser Gly Val Gln Lys Tyr Thr Arg Ala Leu His Asp Ser Ser 
            100                 105                 110         


Ile Thr Gly Ile Ser Pro Ile Thr Glu Tyr Leu Ala Ser Leu Ser Thr 
        115                 120                 125             


Tyr Asn Asp Gln Ser Ile Thr Phe Ala Leu Glu Asp Glu Ser Tyr Glu 
    130                 135                 140                 


Ile Tyr Val Glu Asp Leu Lys Lys Asp Glu Lys Lys Asp Lys Val Leu 
145                 150                 155                 160 


Leu Ser Tyr Tyr Glu Ser Gln His Pro Ser Asn Glu Ser Gly Asp Gly 
                165                 170                 175     


Val Asp Gly Lys Met Leu Met Val Thr Leu Ser Pro Thr Lys Asp Phe 
            180                 185                 190         


Trp Leu His Ala Asn Asn Lys Glu His Ser Val Glu Leu His Lys Cys 
        195                 200                 205             


Glu Lys Pro Leu Pro Asp Gln Ala Phe Phe Val Leu His Asn Met His 
    210                 215                 220                 


Ser Asn Cys Val Ser Phe Glu Cys Lys Thr Asp Pro Gly Val Phe Ile 
225                 230                 235                 240 


Gly Val Lys Asp Asn His Leu Ala Leu Ile Lys Val Asp Ser Ser Glu 
                245                 250                 255     


Asn Leu Cys Thr Glu Asn Ile Leu Phe Lys Leu Ser Glu Thr 
            260                 265                 270 


<210>  697
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  697

Asn Glu Pro Leu Glu Met Trp Pro Leu Thr Gln Asn Glu Glu Cys Thr 
1               5                   10                  15      


Val Thr Gly Phe Leu Arg Asp Lys Leu Gln Tyr Arg Ser Arg Leu Gln 
            20                  25                  30          


Tyr Met Lys His Tyr Phe Pro Ile Asn Tyr Lys Ile Ser Val Pro Tyr 
        35                  40                  45              


Glu Gly Val Phe Arg Ile Ala Asn Val Thr Arg Leu Gln Arg Ala Gln 
    50                  55                  60                  


Val Ser Glu Arg Glu Leu Arg Tyr Leu Trp Val Leu Val Ser Leu Ser 
65                  70                  75                  80  


Ala Thr Glu Ser Val Gln Asp Val Leu Leu Glu Gly His Pro Ser Trp 
                85                  90                  95      


Lys Tyr Leu Gln Glu Val Gln Thr Leu Leu Leu Asn Val Gln Gln Gly 
            100                 105                 110         


Leu Thr Asp Val Glu Val Ser Pro Lys Val Glu Ser Val Leu Ser Leu 
        115                 120                 125             


Leu Asn Ala Pro Gly Pro Asn Leu Lys Leu Val Arg Pro Lys Ala Leu 
    130                 135                 140                 


Leu Asp Asn Cys Phe Arg Val Met Glu Leu Leu Tyr Cys Ser Cys Cys 
145                 150                 155                 160 


Lys Gln Ser Ser Val Leu Asn Trp Gln Asp Cys Glu Val Pro Ser Pro 
                165                 170                 175     


Gln Ser Cys Ser Pro Glu Pro Ser Leu Gln Tyr Ala Ala Thr Gln Leu 
            180                 185                 190         


Tyr Pro Pro Pro Pro Trp Ser Pro Ser Ser Pro Pro His Ser Thr Gly 
        195                 200                 205             


Ser Val Arg Pro Val Arg Ala Gln Gly Glu Gly Leu Leu Pro 
    210                 215                 220         


<210>  698
<211>  153
<212>  PRT
<213>  Homo Sapiens

<400>  698

Arg Glu Ala Ala Pro Lys Ser Tyr Ala Ile Arg Asp Ser Arg Gln Met 
1               5                   10                  15      


Val Trp Val Leu Ser Gly Asn Ser Leu Ile Ala Ala Pro Leu Ser Arg 
            20                  25                  30          


Ser Ile Lys Pro Val Thr Leu His Leu Ile Ala Cys Arg Asp Thr Glu 
        35                  40                  45              


Phe Ser Asp Lys Glu Lys Gly Asn Met Val Tyr Leu Gly Ile Lys Gly 
    50                  55                  60                  


Lys Asp Leu Cys Leu Phe Cys Ala Glu Ile Gln Gly Lys Pro Thr Leu 
65                  70                  75                  80  


Gln Leu Lys Glu Lys Asn Ile Met Asp Leu Tyr Val Glu Lys Lys Ala 
                85                  90                  95      


Gln Lys Pro Phe Leu Phe Phe His Asn Lys Glu Gly Ser Thr Ser Val 
            100                 105                 110         


Phe Gln Ser Val Ser Tyr Pro Gly Trp Phe Ile Ala Thr Ser Thr Thr 
        115                 120                 125             


Ser Gly Gln Pro Ile Phe Leu Thr Lys Glu Arg Gly Ile Thr Asn Asn 
    130                 135                 140                 


Thr Asn Phe Tyr Leu Asp Ser Val Glu 
145                 150             


<210>  699
<211>  287
<212>  PRT
<213>  Homo Sapiens

<400>  699

Thr Lys Glu Asp Pro Asn Pro Pro Ile Thr Asn Leu Arg Met Lys Ala 
1               5                   10                  15      


Lys Ala Gln Gln Leu Thr Trp Asp Leu Asn Arg Asn Val Thr Asp Ile 
            20                  25                  30          


Glu Cys Val Lys Asp Ala Asp Tyr Ser Met Pro Ala Val Asn Asn Ser 
        35                  40                  45              


Tyr Cys Gln Phe Gly Ala Ile Ser Leu Cys Glu Val Thr Asn Tyr Thr 
    50                  55                  60                  


Val Arg Val Ala Asn Pro Pro Phe Ser Thr Trp Ile Leu Phe Pro Glu 
65                  70                  75                  80  


Asn Ser Gly Lys Pro Trp Ala Gly Ala Glu Asn Leu Thr Cys Trp Ile 
                85                  90                  95      


His Asp Val Asp Phe Leu Ser Cys Ser Trp Ala Val Gly Pro Gly Ala 
            100                 105                 110         


Pro Ala Asp Val Gln Tyr Asp Leu Tyr Leu Asn Val Ala Asn Arg Arg 
        115                 120                 125             


Gln Gln Tyr Glu Cys Leu His Tyr Lys Thr Asp Ala Gln Gly Thr Arg 
    130                 135                 140                 


Ile Gly Cys Arg Phe Asp Asp Ile Ser Arg Leu Ser Ser Gly Ser Gln 
145                 150                 155                 160 


Ser Ser His Ile Leu Val Arg Gly Arg Ser Ala Ala Phe Gly Ile Pro 
                165                 170                 175     


Cys Thr Asp Lys Phe Val Val Phe Ser Gln Ile Glu Ile Leu Thr Pro 
            180                 185                 190         


Pro Asn Met Thr Ala Lys Cys Asn Lys Thr His Ser Phe Met His Trp 
        195                 200                 205             


Lys Met Arg Ser His Phe Asn Arg Lys Phe Arg Tyr Glu Leu Gln Ile 
    210                 215                 220                 


Gln Lys Arg Met Gln Pro Val Ile Thr Glu Gln Val Arg Asp Arg Thr 
225                 230                 235                 240 


Ser Phe Gln Leu Leu Asn Pro Gly Thr Tyr Thr Val Gln Ile Arg Ala 
                245                 250                 255     


Arg Glu Arg Val Tyr Glu Phe Leu Ser Ala Trp Ser Thr Pro Gln Arg 
            260                 265                 270         


Phe Glu Cys Asp Gln Glu Glu Gly Ala Asn Thr Arg Ala Trp Arg 
        275                 280                 285         


<210>  700
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  700

His Lys Cys Asp Ile Thr Leu Gln Glu Ile Ile Lys Thr Leu Asn Ser 
1               5                   10                  15      


Leu Thr Glu Gln Lys Thr Leu Cys Thr Glu Leu Thr Val Thr Asp Ile 
            20                  25                  30          


Phe Ala Ala Ser Lys Asn Thr Thr Glu Lys Glu Thr Phe Cys Arg Ala 
        35                  40                  45              


Ala Thr Val Leu Arg Gln Phe Tyr Ser His His Glu Lys Asp Thr Arg 
    50                  55                  60                  


Cys Leu Gly Ala Thr Ala Gln Gln Phe His Arg His Lys Gln Leu Ile 
65                  70                  75                  80  


Arg Phe Leu Lys Arg Leu Asp Arg Asn Leu Trp Gly Leu Ala Gly Leu 
                85                  90                  95      


Asn Ser Cys Pro Val Lys Glu Ala Asn Gln Ser Thr Leu Glu Asn Phe 
            100                 105                 110         


Leu Glu Arg Leu Lys Thr Ile Met Arg Glu Lys Tyr Ser Lys Cys Ser 
        115                 120                 125             


Ser 
    


<210>  701
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  701

Met Lys Val Leu Gln Glu Pro Thr Cys Val Ser Asp Tyr Met Ser Ile 
1               5                   10                  15      


Ser Thr Cys Glu Trp Lys Met Asn Gly Pro Thr Asn Cys Ser Thr Glu 
            20                  25                  30          


Leu Arg Leu Leu Tyr Gln Leu Val Phe Leu Leu Ser Glu Ala His Thr 
        35                  40                  45              


Cys Val Pro Glu Asn Asn Gly Gly Ala Gly Cys Val Cys His Leu Leu 
    50                  55                  60                  


Met Asp Asp Val Val Ser Ala Asp Asn Tyr Thr Leu Asp Leu Trp Ala 
65                  70                  75                  80  


Gly Gln Gln Leu Leu Trp Lys Gly Ser Phe Lys Pro Ser Glu His Val 
                85                  90                  95      


Lys Pro Arg Ala Pro Gly Asn Leu Thr Val His Thr Asn Val Ser Asp 
            100                 105                 110         


Thr Leu Leu Leu Thr Trp Ser Asn Pro Tyr Pro Pro Asp Asn Tyr Leu 
        115                 120                 125             


Tyr Asn His Leu Thr Tyr Ala Val Asn Ile Trp Ser Glu Asn Asp Pro 
    130                 135                 140                 


Ala Asp Phe Arg Ile Tyr Asn Val Thr Tyr Leu Glu Pro Ser Leu Arg 
145                 150                 155                 160 


Ile Ala Ala Ser Thr Leu Lys Ser Gly Ile Ser Tyr Arg Ala Arg Val 
                165                 170                 175     


Arg Ala Trp Ala Gln Cys Tyr Asn Thr Thr Trp Ser Glu Trp Ser Pro 
            180                 185                 190         


Ser Thr Lys Trp His Asn Ser Tyr Arg Glu Pro Phe Glu Gln His 
        195                 200                 205         


<210>  702
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  702

Ile Pro Thr Glu Ile Pro Thr Ser Ala Leu Val Lys Glu Thr Leu Ala 
1               5                   10                  15      


Leu Leu Ser Thr His Arg Thr Leu Leu Ile Ala Asn Glu Thr Leu Arg 
            20                  25                  30          


Ile Pro Val Pro Val His Lys Asn His Gln Leu Cys Thr Glu Glu Ile 
        35                  40                  45              


Phe Gln Gly Ile Gly Thr Leu Glu Ser Gln Thr Val Gln Gly Gly Thr 
    50                  55                  60                  


Val Glu Arg Leu Phe Lys Asn Leu Ser Leu Ile Lys Lys Tyr Ile Asp 
65                  70                  75                  80  


Gly Gln Lys Lys Lys Cys Gly Glu Glu Arg Arg Arg Val Asn Gln Phe 
                85                  90                  95      


Leu Asp Tyr Leu Gln Glu Phe Leu Gly Val Met Asn Thr Glu Trp Ile 
            100                 105                 110         


Ile Glu Ser 
        115 


<210>  703
<211>  315
<212>  PRT
<213>  Homo Sapiens

<400>  703

Asp Leu Leu Pro Asp Glu Lys Ile Ser Leu Leu Pro Pro Val Asn Phe 
1               5                   10                  15      


Thr Ile Lys Val Thr Gly Leu Ala Gln Val Leu Leu Gln Trp Lys Pro 
            20                  25                  30          


Asn Pro Asp Gln Glu Gln Arg Asn Val Asn Leu Glu Tyr Gln Val Lys 
        35                  40                  45              


Ile Asn Ala Pro Lys Glu Asp Asp Tyr Glu Thr Arg Ile Thr Glu Ser 
    50                  55                  60                  


Lys Cys Val Thr Ile Leu His Lys Gly Phe Ser Ala Ser Val Arg Thr 
65                  70                  75                  80  


Ile Leu Gln Asn Asp His Ser Leu Leu Ala Ser Ser Trp Ala Ser Ala 
                85                  90                  95      


Glu Leu His Ala Pro Pro Gly Ser Pro Gly Thr Ser Ile Val Asn Leu 
            100                 105                 110         


Thr Cys Thr Thr Asn Thr Thr Glu Asp Asn Tyr Ser Arg Leu Arg Ser 
        115                 120                 125             


Tyr Gln Val Ser Leu His Cys Thr Trp Leu Val Gly Thr Asp Ala Pro 
    130                 135                 140                 


Glu Asp Thr Gln Tyr Phe Leu Tyr Tyr Arg Tyr Gly Ser Trp Thr Glu 
145                 150                 155                 160 


Glu Cys Gln Glu Tyr Ser Lys Asp Thr Leu Gly Arg Asn Ile Ala Cys 
                165                 170                 175     


Trp Phe Pro Arg Thr Phe Ile Leu Ser Lys Gly Arg Asp Trp Leu Ala 
            180                 185                 190         


Val Leu Val Asp Gly Ser Ser Lys His Ser Ala Ile Arg Pro Phe Asp 
        195                 200                 205             


Gln Leu Phe Ala Leu His Ala Ile Asp Gln Ile Asn Pro Pro Leu Asn 
    210                 215                 220                 


Val Thr Ala Glu Ile Glu Gly Thr Arg Leu Ser Ile Gln Trp Glu Lys 
225                 230                 235                 240 


Pro Val Ser Ala Phe Pro Ile His Cys Phe Asp Tyr Glu Val Lys Ile 
                245                 250                 255     


His Asn Thr Arg Asn Gly Tyr Leu Gln Ile Glu Lys Leu Met Thr Asn 
            260                 265                 270         


Ala Phe Ile Ser Ile Ile Asp Asp Leu Ser Lys Tyr Asp Val Gln Val 
        275                 280                 285             


Arg Ala Ala Val Ser Ser Met Cys Arg Glu Ala Gly Leu Trp Ser Glu 
    290                 295                 300                 


Trp Ser Gln Pro Ile Tyr Val Gly Phe Ser Arg 
305                 310                 315 


<210>  704
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  704

Val Pro Pro Gly Glu Asp Ser Lys Asp Val Ala Ala Pro His Arg Gln 
1               5                   10                  15      


Pro Leu Thr Ser Ser Glu Arg Ile Asp Lys Gln Ile Arg Tyr Ile Leu 
            20                  25                  30          


Asp Gly Ile Ser Ala Leu Arg Lys Glu Thr Cys Asn Lys Ser Asn Met 
        35                  40                  45              


Cys Glu Ser Ser Lys Glu Ala Leu Ala Glu Asn Asn Leu Asn Leu Pro 
    50                  55                  60                  


Lys Met Ala Glu Lys Asp Gly Cys Phe Gln Ser Gly Phe Asn Glu Glu 
65                  70                  75                  80  


Thr Cys Leu Val Lys Ile Ile Thr Gly Leu Leu Glu Phe Glu Val Tyr 
                85                  90                  95      


Leu Glu Tyr Leu Gln Asn Arg Phe Glu Ser Ser Glu Glu Gln Ala Arg 
            100                 105                 110         


Ala Val Gln Met Ser Thr Lys Val Leu Ile Gln Phe Leu Gln Lys Lys 
        115                 120                 125             


Ala Lys Asn Leu Asp Ala Ile Thr Thr Pro Asp Pro Thr Thr Asn Ala 
    130                 135                 140                 


Ser Leu Leu Thr Lys Leu Gln Ala Gln Asn Gln Trp Leu Gln Asp Met 
145                 150                 155                 160 


Thr Thr His Leu Ile Leu Arg Ser Phe Lys Glu Phe Leu Gln Ser Ser 
                165                 170                 175     


Leu Arg Ala Leu Arg Gln Met 
            180             


<210>  705
<211>  346
<212>  PRT
<213>  Homo Sapiens

<400>  705

Leu Ala Pro Arg Arg Cys Pro Ala Gln Glu Val Ala Arg Gly Val Leu 
1               5                   10                  15      


Thr Ser Leu Pro Gly Asp Ser Val Thr Leu Thr Cys Pro Gly Val Glu 
            20                  25                  30          


Pro Glu Asp Asn Ala Thr Val His Trp Val Leu Arg Lys Pro Ala Ala 
        35                  40                  45              


Gly Ser His Pro Ser Arg Trp Ala Gly Met Gly Arg Arg Leu Leu Leu 
    50                  55                  60                  


Arg Ser Val Gln Leu His Asp Ser Gly Asn Tyr Ser Cys Tyr Arg Ala 
65                  70                  75                  80  


Gly Arg Pro Ala Gly Thr Val His Leu Leu Val Asp Val Pro Pro Glu 
                85                  90                  95      


Glu Pro Gln Leu Ser Cys Phe Arg Lys Ser Pro Leu Ser Asn Val Val 
            100                 105                 110         


Cys Glu Trp Gly Pro Arg Ser Thr Pro Ser Leu Thr Thr Lys Ala Val 
        115                 120                 125             


Leu Leu Val Arg Lys Phe Gln Asn Ser Pro Ala Glu Asp Phe Gln Glu 
    130                 135                 140                 


Pro Cys Gln Tyr Ser Gln Glu Ser Gln Lys Phe Ser Cys Gln Leu Ala 
145                 150                 155                 160 


Val Pro Glu Gly Asp Ser Ser Phe Tyr Ile Val Ser Met Cys Val Ala 
                165                 170                 175     


Ser Ser Val Gly Ser Lys Phe Ser Lys Thr Gln Thr Phe Gln Gly Cys 
            180                 185                 190         


Gly Ile Leu Gln Pro Asp Pro Pro Ala Asn Ile Thr Val Thr Ala Val 
        195                 200                 205             


Ala Arg Asn Pro Arg Trp Leu Ser Val Thr Trp Gln Asp Pro His Ser 
    210                 215                 220                 


Trp Asn Ser Ser Phe Tyr Arg Leu Arg Phe Glu Leu Arg Tyr Arg Ala 
225                 230                 235                 240 


Glu Arg Ser Lys Thr Phe Thr Thr Trp Met Val Lys Asp Leu Gln His 
                245                 250                 255     


His Cys Val Ile His Asp Ala Trp Ser Gly Leu Arg His Val Val Gln 
            260                 265                 270         


Leu Arg Ala Gln Glu Glu Phe Gly Gln Gly Glu Trp Ser Glu Trp Ser 
        275                 280                 285             


Pro Glu Ala Met Gly Thr Pro Trp Thr Glu Ser Arg Ser Pro Pro Ala 
    290                 295                 300                 


Glu Asn Glu Val Ser Thr Pro Met Gln Ala Leu Thr Thr Asn Lys Asp 
305                 310                 315                 320 


Asp Asp Asn Ile Leu Phe Arg Asp Ser Ala Asn Ala Thr Ser Leu Pro 
                325                 330                 335     


Val Gln Asp Ser Ser Ser Val Pro Leu Pro 
            340                 345     


<210>  706
<211>  597
<212>  PRT
<213>  Homo Sapiens

<400>  706

Glu Leu Leu Asp Pro Cys Gly Tyr Ile Ser Pro Glu Ser Pro Val Val 
1               5                   10                  15      


Gln Leu His Ser Asn Phe Thr Ala Val Cys Val Leu Lys Glu Lys Cys 
            20                  25                  30          


Met Asp Tyr Phe His Val Asn Ala Asn Tyr Ile Val Trp Lys Thr Asn 
        35                  40                  45              


His Phe Thr Ile Pro Lys Glu Gln Tyr Thr Ile Ile Asn Arg Thr Ala 
    50                  55                  60                  


Ser Ser Val Thr Phe Thr Asp Ile Ala Ser Leu Asn Ile Gln Leu Thr 
65                  70                  75                  80  


Cys Asn Ile Leu Thr Phe Gly Gln Leu Glu Gln Asn Val Tyr Gly Ile 
                85                  90                  95      


Thr Ile Ile Ser Gly Leu Pro Pro Glu Lys Pro Lys Asn Leu Ser Cys 
            100                 105                 110         


Ile Val Asn Glu Gly Lys Lys Met Arg Cys Glu Trp Asp Arg Gly Arg 
        115                 120                 125             


Glu Thr His Leu Glu Thr Asn Phe Thr Leu Lys Ser Glu Trp Ala Thr 
    130                 135                 140                 


His Lys Phe Ala Asp Cys Lys Ala Lys Arg Asp Thr Pro Thr Ser Cys 
145                 150                 155                 160 


Thr Val Asp Tyr Ser Thr Val Tyr Phe Val Asn Ile Glu Val Trp Val 
                165                 170                 175     


Glu Ala Glu Asn Ala Leu Gly Lys Val Thr Ser Asp His Ile Asn Phe 
            180                 185                 190         


Asp Pro Val Tyr Lys Val Lys Pro Asn Pro Pro His Asn Leu Ser Val 
        195                 200                 205             


Ile Asn Ser Glu Glu Leu Ser Ser Ile Leu Lys Leu Thr Trp Thr Asn 
    210                 215                 220                 


Pro Ser Ile Lys Ser Val Ile Ile Leu Lys Tyr Asn Ile Gln Tyr Arg 
225                 230                 235                 240 


Thr Lys Asp Ala Ser Thr Trp Ser Gln Ile Pro Pro Glu Asp Thr Ala 
                245                 250                 255     


Ser Thr Arg Ser Ser Phe Thr Val Gln Asp Leu Lys Pro Phe Thr Glu 
            260                 265                 270         


Tyr Val Phe Arg Ile Arg Cys Met Lys Glu Asp Gly Lys Gly Tyr Trp 
        275                 280                 285             


Ser Asp Trp Ser Glu Glu Ala Ser Gly Ile Thr Tyr Glu Asp Arg Pro 
    290                 295                 300                 


Ser Lys Ala Pro Ser Phe Trp Tyr Lys Ile Asp Pro Ser His Thr Gln 
305                 310                 315                 320 


Gly Tyr Arg Thr Val Gln Leu Val Trp Lys Thr Leu Pro Pro Phe Glu 
                325                 330                 335     


Ala Asn Gly Lys Ile Leu Asp Tyr Glu Val Thr Leu Thr Arg Trp Lys 
            340                 345                 350         


Ser His Leu Gln Asn Tyr Thr Val Asn Ala Thr Lys Leu Thr Val Asn 
        355                 360                 365             


Leu Thr Asn Asp Arg Tyr Val Ala Thr Leu Thr Val Arg Asn Leu Val 
    370                 375                 380                 


Gly Lys Ser Asp Ala Ala Val Leu Thr Ile Pro Ala Cys Asp Phe Gln 
385                 390                 395                 400 


Ala Thr His Pro Val Met Asp Leu Lys Ala Phe Pro Lys Asp Asn Met 
                405                 410                 415     


Leu Trp Val Glu Trp Thr Thr Pro Arg Glu Ser Val Lys Lys Tyr Ile 
            420                 425                 430         


Leu Glu Trp Cys Val Leu Ser Asp Lys Ala Pro Cys Ile Thr Asp Trp 
        435                 440                 445             


Gln Gln Glu Asp Gly Thr Val His Arg Thr Tyr Leu Arg Gly Asn Leu 
    450                 455                 460                 


Ala Glu Ser Lys Cys Tyr Leu Ile Thr Val Thr Pro Val Tyr Ala Asp 
465                 470                 475                 480 


Gly Pro Gly Ser Pro Glu Ser Ile Lys Ala Tyr Leu Lys Gln Ala Pro 
                485                 490                 495     


Pro Ser Lys Gly Pro Thr Val Arg Thr Lys Lys Val Gly Lys Asn Glu 
            500                 505                 510         


Ala Val Leu Glu Trp Asp Gln Leu Pro Val Asp Val Gln Asn Gly Phe 
        515                 520                 525             


Ile Arg Asn Tyr Thr Ile Phe Tyr Arg Thr Ile Ile Gly Asn Glu Thr 
    530                 535                 540                 


Ala Val Asn Val Asp Ser Ser His Thr Glu Tyr Thr Leu Ser Ser Leu 
545                 550                 555                 560 


Thr Ser Asp Thr Leu Tyr Met Val Arg Met Ala Ala Tyr Thr Asp Glu 
                565                 570                 575     


Gly Gly Lys Asp Gly Pro Glu Phe Thr Phe Thr Thr Pro Lys Phe Ala 
            580                 585                 590         


Gln Gly Glu Ile Glu 
        595         


<210>  707
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  707

Asp Cys Asp Ile Glu Gly Lys Asp Gly Lys Gln Tyr Glu Ser Val Leu 
1               5                   10                  15      


Met Val Ser Ile Asp Gln Leu Leu Asp Ser Met Lys Glu Ile Gly Ser 
            20                  25                  30          


Asn Cys Leu Asn Asn Glu Phe Asn Phe Phe Lys Arg His Ile Cys Asp 
        35                  40                  45              


Ala Asn Lys Glu Gly Met Phe Leu Phe Arg Ala Ala Arg Lys Leu Arg 
    50                  55                  60                  


Gln Phe Leu Lys Met Asn Ser Thr Gly Asp Phe Asp Leu His Leu Leu 
65                  70                  75                  80  


Lys Val Ser Glu Gly Thr Thr Ile Leu Leu Asn Cys Thr Gly Gln Val 
                85                  90                  95      


Lys Gly Arg Lys Pro Ala Ala Leu Gly Glu Ala Gln Pro Thr Lys Ser 
            100                 105                 110         


Leu Glu Glu Asn Lys Ser Leu Lys Glu Gln Lys Lys Leu Asn Asp Leu 
        115                 120                 125             


Cys Phe Leu Lys Arg Leu Leu Gln Glu Ile Lys Thr Cys Trp Asn Lys 
    130                 135                 140                 


Ile Leu Met Gly Thr Lys Glu His 
145                 150         


<210>  708
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  708

Glu Ser Gly Tyr Ala Gln Asn Gly Asp Leu Glu Asp Ala Glu Leu Asp 
1               5                   10                  15      


Asp Tyr Ser Phe Ser Cys Tyr Ser Gln Leu Glu Val Asn Gly Ser Gln 
            20                  25                  30          


His Ser Leu Thr Cys Ala Phe Glu Asp Pro Asp Val Asn Ile Thr Asn 
        35                  40                  45              


Leu Glu Phe Glu Ile Cys Gly Ala Leu Val Glu Val Lys Cys Leu Asn 
    50                  55                  60                  


Phe Arg Lys Leu Gln Glu Ile Tyr Phe Ile Glu Thr Lys Lys Phe Leu 
65                  70                  75                  80  


Leu Ile Gly Lys Ser Asn Ile Cys Val Lys Val Gly Glu Lys Ser Leu 
                85                  90                  95      


Thr Cys Lys Lys Ile Asp Leu Thr Thr Ile Val Lys Pro Glu Ala Pro 
            100                 105                 110         


Phe Asp Leu Ser Val Val Tyr Arg Glu Gly Ala Asn Asp Phe Val Val 
        115                 120                 125             


Thr Phe Asn Thr Ser His Leu Gln Lys Lys Tyr Val Lys Val Leu Met 
    130                 135                 140                 


His Asp Val Ala Tyr Arg Gln Glu Lys Asp Glu Asn Lys Trp Thr His 
145                 150                 155                 160 


Val Asn Leu Ser Ser Thr Lys Leu Thr Leu Leu Gln Arg Lys Leu Gln 
                165                 170                 175     


Pro Ala Ala Met Tyr Glu Ile Lys Val Arg Ser Ile Pro Asp His Tyr 
            180                 185                 190         


Phe Lys Gly Phe Trp Ser Glu Trp Ser Pro Ser Tyr Tyr Phe Arg Thr 
        195                 200                 205             


Pro Glu Ile Asn Asn Ser Ser Gly Glu Met Asp 
    210                 215                 


<210>  709
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  709

Ala Val Leu Pro Arg Ser Ala Lys Glu Leu Arg Cys Gln Cys Ile Lys 
1               5                   10                  15      


Thr Tyr Ser Lys Pro Phe His Pro Lys Phe Ile Lys Glu Leu Arg Val 
            20                  25                  30          


Ile Glu Ser Gly Pro His Cys Ala Asn Thr Glu Ile Ile Val Lys Leu 
        35                  40                  45              


Ser Asp Gly Arg Glu Leu Cys Leu Asp Pro Lys Glu Asn Trp Val Gln 
    50                  55                  60                  


Arg Val Val Glu Lys Phe Leu Lys Arg Ala Glu Asn Ser 
65                  70                  75          


<210>  710
<211>  48
<212>  PRT
<213>  Homo Sapiens

<400>  710

Met Glu Asp Phe Asn Met Glu Ser Asp Ser Phe Glu Asp Phe Trp Lys 
1               5                   10                  15      


Gly Glu Asp Leu Ser Asn Tyr Ser Tyr Ser Ser Thr Leu Pro Pro Phe 
            20                  25                  30          


Leu Leu Asp Ala Ala Pro Cys Glu Pro Glu Ser Leu Glu Ile Asn Lys 
        35                  40                  45              


<210>  711
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  711

Gln Gly Cys Pro Thr Leu Ala Gly Ile Leu Asp Ile Asn Phe Leu Ile 
1               5                   10                  15      


Asn Lys Met Gln Glu Asp Pro Ala Ser Lys Cys His Cys Ser Ala Asn 
            20                  25                  30          


Val Thr Ser Cys Leu Cys Leu Gly Ile Pro Ser Asp Asn Cys Thr Arg 
        35                  40                  45              


Pro Cys Phe Ser Glu Arg Leu Ser Gln Met Thr Asn Thr Thr Met Gln 
    50                  55                  60                  


Thr Arg Tyr Pro Leu Ile Phe Ser Arg Val Lys Lys Ser Val Glu Val 
65                  70                  75                  80  


Leu Lys Asn Asn Lys Cys Pro Tyr Phe Ser Cys Glu Gln Pro Cys Asn 
                85                  90                  95      


Gln Thr Thr Ala Gly Asn Ala Leu Thr Phe Leu Lys Ser Leu Leu Glu 
            100                 105                 110         


Ile Phe Gln Lys Glu Lys Met Arg Gly Met Arg Gly Lys Ile 
        115                 120                 125     


<210>  712
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  712

Ser Val Thr Gly Glu Gly Gln Gly Pro Arg Ser Arg Thr Phe Thr Cys 
1               5                   10                  15      


Leu Thr Asn Asn Ile Leu Arg Ile Asp Cys His Trp Ser Ala Pro Glu 
            20                  25                  30          


Leu Gly Gln Gly Ser Ser Pro Trp Leu Leu Phe Thr Arg Leu Leu Ala 
        35                  40                  45              


Ala His Ile Ser Ala Ser Cys Gly Ala Val Ser Ala Pro Ser Cys Cys 
    50                  55                  60                  


His Leu Arg Gln Cys Ser Cys His Leu Thr Ile Ser Pro Ser Leu Ser 
65                  70                  75                  80  


Thr Thr Ala Cys Leu Gly Gly Ser Arg Ser Ala Trp Trp Thr Arg Ser 
                85                  90                  95      


Thr Cys Pro Gly Asp Thr Ser Asn Ile Ser Ser Gly His Cys Ile Leu 
            100                 105                 110         


Thr Trp Ser Ile Ser Pro Ala Leu Glu Pro Met Thr Thr Leu Leu Ser 
        115                 120                 125             


Tyr Glu Leu Ala Phe Lys Lys Gln Glu Glu Ala Trp Glu Gln Ala Gln 
    130                 135                 140                 


His Arg Asp His Ile Val Gly Val Thr Trp Leu Ile Leu Glu Ala Phe 
145                 150                 155                 160 


Glu Leu Asp Pro Gly Phe Ile His Glu Ala Arg Leu Arg Val Gln Met 
                165                 170                 175     


Ala Thr Leu Glu Asp Asp Val Val Glu Glu Glu Arg Tyr Thr Gly Gln 
            180                 185                 190         


Trp Ser Glu Trp Ser Gln Pro Val Cys Phe Gln Ala Pro Gln Arg Gln 
        195                 200                 205             


Gly Pro Leu Ile Pro Pro Trp Gly Trp Pro 
    210                 215             


<210>  713
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  713

Leu Leu Val Thr Val Gln His Thr Glu Arg Tyr Val Thr Leu Phe Ala 
1               5                   10                  15      


Ser Ile Ile Leu Lys Cys Asp Tyr Thr Thr Ser Ala Gln Leu Gln Asp 
            20                  25                  30          


Val Val Val Thr Trp Arg Phe Lys Ser Phe Cys Lys Asp Pro Ile Phe 
        35                  40                  45              


Asp Tyr Tyr Ser Ala Ser Tyr Gln Ala Ala Leu Ser Leu Gly Gln Asp 
    50                  55                  60                  


Pro Ser Asn Asp Cys Asn Asp Asn Gln Arg Glu Val Arg Ile Val Ala 
65                  70                  75                  80  


Gln Arg Arg Gly Gln Asn Glu Pro Val Leu Gly Val Asp Tyr Arg Gln 
                85                  90                  95      


Arg Lys Ile Thr Ile Gln Asn Arg Ala Asp Leu Val Ile Asn Glu Val 
            100                 105                 110         


Met Trp Trp Asp His Gly Val Tyr Tyr Cys Thr Ile Glu Ala Pro Gly 
        115                 120                 125             


Asp Thr Ser Gly Asp Pro Asp Lys Glu Val Lys Leu Ile Val Leu His 
    130                 135                 140                 


<210>  714
<211>  861
<212>  PRT
<213>  Homo Sapiens

<400>  714

Gly Glu Gln Ile Ala Glu Phe Ser Ile His Leu Leu Gly Lys Gln Tyr 
1               5                   10                  15      


Arg Glu Glu Leu Gln Asp Ser Ser Ser Phe His His Gln His Leu Glu 
            20                  25                  30          


Glu Glu Phe Ile Ser Glu Val Glu Asn Ala Phe Thr Gly Leu Pro Gly 
        35                  40                  45              


Tyr Lys Glu Ile Arg Val Leu Glu Phe Arg Ser Pro Lys Glu Asn Asp 
    50                  55                  60                  


Ser Gly Val Asp Val Tyr Tyr Ala Val Thr Phe Asn Gly Glu Ala Ile 
65                  70                  75                  80  


Ser Asn Thr Thr Trp Asp Leu Ile Ser Leu His Ser Asn Lys Val Glu 
                85                  90                  95      


Asn His Gly Leu Val Glu Leu Asp Asp Lys Pro Thr Val Val Tyr Thr 
            100                 105                 110         


Ile Ser Asn Phe Arg Asp Tyr Ile Ala Glu Thr Leu Gln Gln Asn Phe 
        115                 120                 125             


Leu Leu Gly Asn Ser Ser Leu Asn Pro Asp Pro Asp Ser Leu Gln Leu 
    130                 135                 140                 


Ile Asn Val Arg Gly Val Leu Arg His Gln Thr Glu Asp Leu Val Trp 
145                 150                 155                 160 


Asn Thr Gln Ser Ser Ser Leu Gln Ala Thr Pro Ser Ser Ile Leu Asp 
                165                 170                 175     


Asn Thr Phe Gln Ala Ala Trp Pro Ser Ala Asp Glu Ser Ile Thr Ser 
            180                 185                 190         


Ser Ile Pro Pro Leu Asp Phe Ser Ser Gly Pro Pro Ser Ala Thr Gly 
        195                 200                 205             


Arg Glu Leu Trp Ser Glu Ser Pro Leu Gly Asp Leu Val Ser Thr His 
    210                 215                 220                 


Lys Leu Ala Phe Pro Ser Lys Met Gly Leu Ser Ser Ser Pro Glu Val 
225                 230                 235                 240 


Leu Glu Val Ser Ser Leu Thr Leu His Ser Val Thr Pro Ala Val Leu 
                245                 250                 255     


Gln Thr Gly Leu Pro Val Ala Ser Glu Glu Arg Thr Ser Gly Ser His 
            260                 265                 270         


Leu Val Glu Asp Gly Leu Ala Asn Val Glu Glu Ser Glu Asp Phe Leu 
        275                 280                 285             


Ser Ile Asp Ser Leu Pro Ser Ser Ser Phe Thr Gln Pro Val Pro Lys 
    290                 295                 300                 


Glu Thr Ile Pro Ser Met Glu Asp Ser Asp Val Ser Leu Thr Ser Ser 
305                 310                 315                 320 


Pro Tyr Leu Thr Ser Ser Ile Pro Phe Gly Leu Asp Ser Leu Thr Ser 
                325                 330                 335     


Lys Val Lys Asp Gln Leu Lys Val Ser Pro Phe Leu Pro Asp Ala Ser 
            340                 345                 350         


Met Glu Lys Glu Leu Ile Phe Asp Gly Gly Leu Gly Ser Gly Ser Gly 
        355                 360                 365             


Gln Lys Val Asp Leu Ile Thr Trp Pro Arg Ser Glu Thr Ser Ser Glu 
    370                 375                 380                 


Lys Ser Ala Glu Pro Leu Ser Lys Pro Trp Leu Glu Asp Asp Asp Ser 
385                 390                 395                 400 


Leu Leu Pro Ala Glu Ile Glu Asp Lys Lys Leu Val Leu Val Asp Lys 
                405                 410                 415     


Met Asp Ser Thr Asp Gln Ile Ser Lys His Ser Lys Tyr Glu His Asp 
            420                 425                 430         


Asp Arg Ser Ile His Phe Pro Glu Glu Glu Pro Leu Ser Gly Pro Ala 
        435                 440                 445             


Val Pro Ile Phe Ala Asp Thr Ala Ala Glu Ser Ala Ser Leu Thr Leu 
    450                 455                 460                 


Pro Lys His Ile Ser Glu Val Pro Gly Val Asp Asp Tyr Ser Val Thr 
465                 470                 475                 480 


Lys Ala Pro Leu Ile Leu Thr Ser Val Ala Ile Ser Ala Ser Thr Asp 
                485                 490                 495     


Lys Ser Asp Gln Ala Asp Ala Ile Leu Arg Glu Asp Met Glu Gln Ile 
            500                 505                 510         


Thr Glu Ser Ser Asn Tyr Glu Trp Phe Asp Ser Glu Val Ser Met Val 
        515                 520                 525             


Lys Pro Asp Met Gln Thr Leu Trp Thr Ile Leu Pro Glu Ser Glu Arg 
    530                 535                 540                 


Val Trp Thr Arg Thr Ser Ser Leu Glu Lys Leu Ser Arg Asp Ile Leu 
545                 550                 555                 560 


Ala Ser Thr Pro Gln Ser Ala Asp Arg Leu Trp Leu Ser Val Thr Gln 
                565                 570                 575     


Ser Thr Lys Leu Pro Pro Thr Thr Ile Ser Thr Leu Leu Glu Asp Glu 
            580                 585                 590         


Val Ile Met Gly Val Gln Asp Ile Ser Leu Glu Leu Asp Arg Ile Gly 
        595                 600                 605             


Thr Asp Tyr Tyr Gln Pro Glu Gln Val Gln Glu Gln Asn Gly Lys Val 
    610                 615                 620                 


Gly Ser Tyr Val Glu Met Ser Thr Ser Val His Ser Thr Glu Met Val 
625                 630                 635                 640 


Ser Val Ala Trp Pro Thr Glu Gly Gly Asp Asp Leu Ser Tyr Thr Gln 
                645                 650                 655     


Thr Ser Gly Ala Leu Val Val Phe Phe Ser Leu Arg Val Thr Asn Met 
            660                 665                 670         


Met Phe Ser Glu Asp Leu Phe Asn Lys Asn Ser Leu Glu Tyr Lys Ala 
        675                 680                 685             


Leu Glu Gln Arg Phe Leu Glu Leu Leu Val Pro Tyr Leu Gln Ser Asn 
    690                 695                 700                 


Leu Thr Gly Phe Gln Asn Leu Glu Ile Leu Asn Phe Arg Asn Gly Ser 
705                 710                 715                 720 


Ile Val Val Asn Ser Arg Met Lys Phe Ala Asn Ser Val Pro Pro Asn 
                725                 730                 735     


Val Asn Asn Ala Val Tyr Met Ile Leu Glu Asp Phe Cys Thr Thr Ala 
            740                 745                 750         


Tyr Asn Thr Met Asn Leu Ala Ile Asp Lys Tyr Ser Leu Asp Val Glu 
        755                 760                 765             


Ser Gly Asp Glu Ala Asn Pro Cys Lys Phe Gln Ala Cys Asn Glu Phe 
    770                 775                 780                 


Ser Glu Cys Leu Val Asn Pro Trp Ser Gly Glu Ala Lys Cys Arg Cys 
785                 790                 795                 800 


Phe Pro Gly Tyr Leu Ser Val Glu Glu Arg Pro Cys Gln Ser Leu Cys 
                805                 810                 815     


Asp Leu Gln Pro Asp Phe Cys Leu Asn Asp Gly Lys Cys Asp Ile Met 
            820                 825                 830         


Pro Gly His Gly Ala Ile Cys Arg Cys Arg Val Gly Glu Asn Trp Trp 
        835                 840                 845             


Tyr Arg Gly Lys His Cys Glu Glu Phe Val Ser Glu Pro 
    850                 855                 860     


<210>  715
<211>  158
<212>  PRT
<213>  Homo Sapiens

<400>  715

Ala Ala Pro Arg Arg Cys Leu Leu Ser His Tyr Arg Ser Leu Glu Pro 
1               5                   10                  15      


Arg Thr Leu Ala Ala Ala Lys Ala Leu Arg Asp Arg Tyr Glu Glu Glu 
            20                  25                  30          


Ala Leu Ser Trp Gly Gln Arg Asn Cys Ser Phe Arg Pro Arg Arg Asp 
        35                  40                  45              


Pro Pro Arg Pro Ser Ser Cys Ala Arg Leu Arg His Val Ala Arg Gly 
    50                  55                  60                  


Ile Ala Asp Ala Gln Ala Val Leu Ser Gly Leu His Arg Ser Glu Leu 
65                  70                  75                  80  


Leu Pro Gly Ala Gly Pro Ile Leu Glu Leu Leu Ala Ala Ala Gly Arg 
                85                  90                  95      


Asp Val Ala Ala Cys Leu Glu Leu Ala Arg Pro Gly Ser Ser Arg Lys 
            100                 105                 110         


Val Pro Gly Ala Gln Lys Arg Arg His Lys Pro Arg Arg Ala Asp Ser 
        115                 120                 125             


Pro Arg Cys Arg Lys Ala Ser Val Val Phe Asn Leu Leu Arg Leu Leu 
    130                 135                 140                 


Thr Trp Glu Leu Arg Leu Ala Ala His Ser Gly Pro Cys Leu 
145                 150                 155             


<210>  716
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  716

Phe Val Asn Gln His Leu Cys Gly Ser His Leu Val Glu Ala Leu Tyr 
1               5                   10                  15      


Leu Val Cys Gly Glu Arg Gly Phe Phe Tyr Thr Pro Lys Thr Arg Arg 
            20                  25                  30          


Glu Ala Glu Asp Leu Gln Val Gly Gln Val Glu Leu Gly Gly Gly Pro 
        35                  40                  45              


Gly Ala Gly Ser Leu Gln Pro Leu Ala Leu Glu Gly Ser Leu Gln Lys 
    50                  55                  60                  


Arg Gly Ile Val Glu Gln Cys Cys Thr Ser Ile Cys Ser Leu Tyr Gln 
65                  70                  75                  80  


Leu Glu Asn Tyr Cys Asn 
                85      


<210>  717
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  717

Leu Gly Pro Ala Pro Thr Pro Glu Met Arg Glu Lys Leu Cys Gly His 
1               5                   10                  15      


His Phe Val Arg Ala Leu Val Arg Val Cys Gly Gly Pro Arg Trp Ser 
            20                  25                  30          


Thr Glu Ala Arg Arg Pro Ala Ala Gly Gly Asp Arg Glu Leu Leu Gln 
        35                  40                  45              


Trp Leu Glu Arg Arg His Leu Leu His Gly Leu Val Ala Asp Ser Asn 
    50                  55                  60                  


Leu Thr Leu Gly Pro Gly Leu Gln Pro Leu Pro Gln Thr Ser His His 
65                  70                  75                  80  


His Arg His His Arg Ala Ala Ala Thr Asn Pro Ala Arg Tyr Cys Cys 
                85                  90                  95      


Leu Ser Gly Cys Thr Gln Gln Asp Leu Leu Thr Leu Cys Pro Tyr 
            100                 105                 110     


<210>  718
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  718

Lys Glu Ser Val Arg Leu Cys Gly Leu Glu Tyr Ile Arg Thr Val Ile 
1               5                   10                  15      


Tyr Ile Cys Ala Ser Ser Arg Trp Arg Arg His Leu Glu Gly Ile Pro 
            20                  25                  30          


Gln Ala Gln Gln Ala Glu Thr Gly Asn Ser Phe Gln Leu Pro His Lys 
        35                  40                  45              


Arg Glu Phe Ser Glu Glu Asn Pro Ala Gln Asn Leu Pro Lys Val Asp 
    50                  55                  60                  


Ala Ser Gly Glu Asp Arg Leu Trp Gly Gly Gln Met Pro Thr Glu Glu 
65                  70                  75                  80  


Leu Trp Lys Ser Lys Lys His Ser Val Met Ser Arg Gln Asp Leu Gln 
                85                  90                  95      


Thr Leu Cys Cys Thr Asp Gly Cys Ser Met Thr Asp Leu Ser Ala Leu 
            100                 105                 110         


Cys 
    


<210>  719
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  719

Arg Glu Leu Ser Asp Ile Ser Ser Ala Arg Lys Leu Cys Gly Arg Tyr 
1               5                   10                  15      


Leu Val Lys Glu Ile Glu Lys Leu Cys Gly His Ala Asn Trp Ser Gln 
            20                  25                  30          


Phe Arg Phe Glu Glu Glu Thr Pro Phe Ser Arg Leu Ile Ala Gln Ala 
        35                  40                  45              


Ser Glu Lys Val Glu Ala Tyr Ser Pro Tyr Gln Phe Glu Ser Pro Gln 
    50                  55                  60                  


Thr Ala Ser Pro Ala Arg Gly Arg Gly Thr Asn Pro Val Ser Thr Ser 
65                  70                  75                  80  


Trp Glu Glu Ala Val Asn Ser Trp Glu Met Gln Ser Leu Pro Glu Tyr 
                85                  90                  95      


Lys Asp Lys Lys Gly Tyr Ser Pro Leu Gly Lys Thr Arg Glu Phe Ser 
            100                 105                 110         


Ser Ser His Asn Ile Asn Val Tyr Ile His Glu Asn Ala Lys Phe Gln 
        115                 120                 125             


Lys Lys Arg Arg Asn Lys Ile Lys Thr Leu Ser Asn Leu Phe Trp Gly 
    130                 135                 140                 


His His Pro Gln Arg Lys Arg Arg Gly Tyr Ser Glu Lys Cys Cys Leu 
145                 150                 155                 160 


Thr Gly Cys Thr Lys Glu Glu Leu Ser Ile Ala Cys Leu Pro Tyr Ile 
                165                 170                 175     


Asp Phe 
        


<210>  720
<211>  719
<212>  PRT
<213>  Homo Sapiens

<400>  720

His Leu Tyr Pro Gly Glu Val Cys Pro Gly Met Asp Ile Arg Asn Asn 
1               5                   10                  15      


Leu Thr Arg Leu His Glu Leu Glu Asn Cys Ser Val Ile Glu Gly His 
            20                  25                  30          


Leu Gln Ile Leu Leu Met Phe Lys Thr Arg Pro Glu Asp Phe Arg Asp 
        35                  40                  45              


Leu Ser Phe Pro Lys Leu Ile Met Ile Thr Asp Tyr Leu Leu Leu Phe 
    50                  55                  60                  


Arg Val Tyr Gly Leu Glu Ser Leu Lys Asp Leu Phe Pro Asn Leu Thr 
65                  70                  75                  80  


Val Ile Arg Gly Ser Arg Leu Phe Phe Asn Tyr Ala Leu Val Ile Phe 
                85                  90                  95      


Glu Met Val His Leu Lys Glu Leu Gly Leu Tyr Asn Leu Met Asn Ile 
            100                 105                 110         


Thr Arg Gly Ser Val Arg Ile Glu Lys Asn Asn Glu Leu Cys Tyr Leu 
        115                 120                 125             


Ala Thr Ile Asp Trp Ser Arg Ile Leu Asp Ser Val Glu Asp Asn Tyr 
    130                 135                 140                 


Ile Val Leu Asn Lys Asp Asp Asn Glu Glu Cys Gly Asp Ile Cys Pro 
145                 150                 155                 160 


Gly Thr Ala Lys Gly Lys Thr Asn Cys Pro Ala Thr Val Ile Asn Gly 
                165                 170                 175     


Gln Phe Val Glu Arg Cys Trp Thr His Ser His Cys Gln Lys Val Cys 
            180                 185                 190         


Pro Thr Ile Cys Lys Ser His Gly Cys Thr Ala Glu Gly Leu Cys Cys 
        195                 200                 205             


His Ser Glu Cys Leu Gly Asn Cys Ser Gln Pro Asp Asp Pro Thr Lys 
    210                 215                 220                 


Cys Val Ala Cys Arg Asn Phe Tyr Leu Asp Gly Arg Cys Val Glu Thr 
225                 230                 235                 240 


Cys Pro Pro Pro Tyr Tyr His Phe Gln Asp Trp Arg Cys Val Asn Phe 
                245                 250                 255     


Ser Phe Cys Gln Asp Leu His His Lys Cys Lys Asn Ser Arg Arg Gln 
            260                 265                 270         


Gly Cys His Gln Tyr Val Ile His Asn Asn Lys Cys Ile Pro Glu Cys 
        275                 280                 285             


Pro Ser Gly Tyr Thr Met Asn Ser Ser Asn Leu Leu Cys Thr Pro Cys 
    290                 295                 300                 


Leu Gly Pro Cys Pro Lys Val Cys His Leu Leu Glu Gly Glu Lys Thr 
305                 310                 315                 320 


Ile Asp Ser Val Thr Ser Ala Gln Glu Leu Arg Gly Cys Thr Val Ile 
                325                 330                 335     


Asn Gly Ser Leu Ile Ile Asn Ile Arg Gly Gly Asn Asn Leu Ala Ala 
            340                 345                 350         


Glu Leu Glu Ala Asn Leu Gly Leu Ile Glu Glu Ile Ser Gly Tyr Leu 
        355                 360                 365             


Lys Ile Arg Arg Ser Tyr Ala Leu Val Ser Leu Ser Phe Phe Arg Lys 
    370                 375                 380                 


Leu Arg Leu Ile Arg Gly Glu Thr Leu Glu Ile Gly Asn Tyr Ser Phe 
385                 390                 395                 400 


Tyr Ala Leu Asp Asn Gln Asn Leu Arg Gln Leu Trp Asp Trp Ser Lys 
                405                 410                 415     


His Asn Leu Thr Ile Thr Gln Gly Lys Leu Phe Phe His Tyr Asn Pro 
            420                 425                 430         


Lys Leu Cys Leu Ser Glu Ile His Lys Met Glu Glu Val Ser Gly Thr 
        435                 440                 445             


Lys Gly Arg Gln Glu Arg Asn Asp Ile Ala Leu Lys Thr Asn Gly Asp 
    450                 455                 460                 


Gln Ala Ser Cys Glu Asn Glu Leu Leu Lys Phe Ser Tyr Ile Arg Thr 
465                 470                 475                 480 


Ser Phe Asp Lys Ile Leu Leu Arg Trp Glu Pro Tyr Trp Pro Pro Asp 
                485                 490                 495     


Phe Arg Asp Leu Leu Gly Phe Met Leu Phe Tyr Lys Glu Ala Pro Tyr 
            500                 505                 510         


Gln Asn Val Thr Glu Phe Asp Gly Gln Asp Ala Cys Gly Ser Asn Ser 
        515                 520                 525             


Trp Thr Val Val Asp Ile Asp Pro Pro Leu Arg Ser Asn Asp Pro Lys 
    530                 535                 540                 


Ser Gln Asn His Pro Gly Trp Leu Met Arg Gly Leu Lys Pro Trp Thr 
545                 550                 555                 560 


Gln Tyr Ala Ile Phe Val Lys Thr Leu Val Thr Phe Ser Asp Glu Arg 
                565                 570                 575     


Arg Thr Tyr Gly Ala Lys Ser Asp Ile Ile Tyr Val Gln Thr Asp Ala 
            580                 585                 590         


Thr Asn Pro Ser Val Pro Leu Asp Pro Ile Ser Val Ser Asn Ser Ser 
        595                 600                 605             


Ser Gln Ile Ile Leu Lys Trp Lys Pro Pro Ser Asp Pro Asn Gly Asn 
    610                 615                 620                 


Ile Thr His Tyr Leu Val Phe Trp Glu Arg Gln Ala Glu Asp Ser Glu 
625                 630                 635                 640 


Leu Phe Glu Leu Asp Tyr Cys Leu Lys Gly Leu Lys Leu Pro Ser Arg 
                645                 650                 655     


Thr Trp Ser Pro Pro Phe Glu Ser Glu Asp Ser Gln Lys His Asn Gln 
            660                 665                 670         


Ser Glu Tyr Glu Asp Ser Ala Gly Glu Cys Cys Ser Cys Pro Lys Thr 
        675                 680                 685             


Asp Ser Gln Ile Leu Lys Glu Leu Glu Glu Ser Ser Phe Arg Lys Thr 
    690                 695                 700                 


Phe Glu Asp Tyr Leu His Asn Val Val Phe Val Pro Arg Pro Ser 
705                 710                 715                 


<210>  721
<211>  410
<212>  PRT
<213>  Homo Sapiens

<400>  721

Cys Pro Glu Pro Cys Asp Cys Gly Glu Lys Tyr Gly Phe Gln Ile Ala 
1               5                   10                  15      


Asp Cys Ala Tyr Arg Asp Leu Glu Ser Val Pro Pro Gly Phe Pro Ala 
            20                  25                  30          


Asn Val Thr Thr Leu Ser Leu Ser Ala Asn Arg Leu Pro Gly Leu Pro 
        35                  40                  45              


Glu Gly Ala Phe Arg Glu Val Pro Leu Leu Gln Ser Leu Trp Leu Ala 
    50                  55                  60                  


His Asn Glu Ile Arg Thr Val Ala Ala Gly Ala Leu Ala Ser Leu Ser 
65                  70                  75                  80  


His Leu Lys Ser Leu Asp Leu Ser His Asn Leu Ile Ser Asp Phe Ala 
                85                  90                  95      


Trp Ser Asp Leu His Asn Leu Ser Ala Leu Gln Leu Leu Lys Met Asp 
            100                 105                 110         


Ser Asn Glu Leu Thr Phe Ile Pro Arg Asp Ala Phe Arg Ser Leu Arg 
        115                 120                 125             


Ala Leu Arg Ser Leu Gln Leu Asn His Asn Arg Leu His Thr Leu Ala 
    130                 135                 140                 


Glu Gly Thr Phe Thr Pro Leu Thr Ala Leu Ser His Leu Gln Ile Asn 
145                 150                 155                 160 


Glu Asn Pro Phe Asp Cys Thr Cys Gly Ile Val Trp Leu Lys Thr Trp 
                165                 170                 175     


Ala Leu Thr Thr Ala Val Ser Ile Pro Glu Gln Asp Asn Ile Ala Cys 
            180                 185                 190         


Thr Ser Pro His Val Leu Lys Gly Thr Pro Leu Ser Arg Leu Pro Pro 
        195                 200                 205             


Leu Pro Cys Ser Ala Pro Ser Val Gln Leu Ser Tyr Gln Pro Ser Gln 
    210                 215                 220                 


Asp Gly Ala Glu Leu Arg Pro Gly Phe Val Leu Ala Leu His Cys Asp 
225                 230                 235                 240 


Val Asp Gly Gln Pro Ala Pro Gln Leu His Trp His Ile Gln Ile Pro 
                245                 250                 255     


Ser Gly Ile Val Glu Ile Thr Ser Pro Asn Val Gly Thr Asp Gly Arg 
            260                 265                 270         


Ala Leu Pro Gly Thr Pro Val Ala Ser Ser Gln Pro Arg Phe Gln Ala 
        275                 280                 285             


Phe Ala Asn Gly Ser Leu Leu Ile Pro Asp Phe Gly Lys Leu Glu Glu 
    290                 295                 300                 


Gly Thr Tyr Ser Cys Leu Ala Thr Asn Glu Leu Gly Ser Ala Glu Ser 
305                 310                 315                 320 


Ser Val Asp Val Ala Leu Ala Thr Pro Gly Glu Gly Gly Glu Asp Thr 
                325                 330                 335     


Leu Gly Arg Arg Phe His Gly Lys Ala Val Glu Gly Lys Gly Cys Tyr 
            340                 345                 350         


Thr Val Asp Asn Glu Val Gln Pro Ser Gly Pro Glu Asp Asn Val Val 
        355                 360                 365             


Ile Ile Tyr Leu Ser Arg Ala Gly Asn Pro Glu Ala Ala Val Ala Glu 
    370                 375                 380                 


Gly Val Pro Gly Gln Leu Pro Pro Gly Leu Leu Leu Leu Gly Gln Ser 
385                 390                 395                 400 


Leu Leu Leu Phe Phe Phe Leu Thr Ser Phe 
                405                 410 


<210>  722
<211>  571
<212>  PRT
<213>  Homo Sapiens

<400>  722

Ser Cys Pro Glu Pro Cys Ala Cys Val Asp Lys Tyr Ala His Gln Phe 
1               5                   10                  15      


Ala Asp Cys Ala Tyr Lys Glu Leu Arg Glu Val Pro Glu Gly Leu Pro 
            20                  25                  30          


Ala Asn Val Thr Thr Leu Ser Leu Ser Ala Asn Lys Ile Thr Val Leu 
        35                  40                  45              


Arg Arg Gly Ala Phe Ala Asp Val Thr Gln Val Thr Ser Leu Trp Leu 
    50                  55                  60                  


Ala His Asn Glu Val Arg Thr Val Glu Pro Gly Ala Leu Ala Val Leu 
65                  70                  75                  80  


Ser Gln Leu Lys Asn Leu Asp Leu Ser His Asn Phe Ile Ser Ser Phe 
                85                  90                  95      


Pro Trp Ser Asp Leu Arg Asn Leu Ser Ala Leu Gln Leu Leu Lys Met 
            100                 105                 110         


Asn His Asn Arg Leu Gly Ser Leu Pro Arg Asp Ala Leu Gly Ala Leu 
        115                 120                 125             


Pro Asp Leu Arg Ser Leu Arg Ile Asn Asn Asn Arg Leu Arg Thr Leu 
    130                 135                 140                 


Ala Pro Gly Thr Phe Asp Ala Leu Ser Ala Leu Ser His Leu Gln Leu 
145                 150                 155                 160 


Tyr His Asn Pro Phe His Cys Gly Cys Gly Leu Val Trp Leu Gln Ala 
                165                 170                 175     


Trp Ala Ala Ser Thr Arg Val Ser Leu Pro Glu Pro Asp Ser Ile Ala 
            180                 185                 190         


Cys Ala Ser Pro Pro Ala Leu Gln Gly Val Pro Val Tyr Arg Leu Pro 
        195                 200                 205             


Ala Leu Pro Cys Ala Pro Pro Ser Val His Leu Ser Ala Glu Pro Pro 
    210                 215                 220                 


Leu Glu Ala Pro Gly Thr Pro Leu Arg Ala Gly Leu Ala Phe Val Leu 
225                 230                 235                 240 


His Cys Ile Ala Asp Gly His Pro Thr Pro Arg Leu Gln Trp Gln Leu 
                245                 250                 255     


Gln Ile Pro Gly Gly Thr Val Val Leu Glu Pro Pro Val Leu Ser Gly 
            260                 265                 270         


Glu Asp Asp Gly Val Gly Ala Glu Glu Gly Glu Gly Glu Gly Asp Gly 
        275                 280                 285             


Asp Leu Leu Thr Gln Thr Gln Ala Gln Thr Pro Thr Pro Ala Pro Ala 
    290                 295                 300                 


Trp Pro Ala Pro Pro Ala Thr Pro Arg Phe Leu Ala Leu Ala Asn Gly 
305                 310                 315                 320 


Ser Leu Leu Val Pro Leu Leu Ser Ala Lys Glu Ala Gly Val Tyr Thr 
                325                 330                 335     


Cys Arg Ala His Asn Glu Leu Gly Ala Asn Ser Thr Ser Ile Arg Val 
            340                 345                 350         


Ala Val Ala Ala Thr Gly Pro Pro Lys His Ala Pro Gly Ala Gly Gly 
        355                 360                 365             


Glu Pro Asp Gly Gln Ala Pro Thr Ser Glu Arg Lys Ser Thr Ala Lys 
    370                 375                 380                 


Gly Arg Gly Asn Ser Val Leu Pro Ser Lys Pro Glu Gly Lys Ile Lys 
385                 390                 395                 400 


Gly Gln Gly Leu Ala Lys Val Ser Ile Leu Gly Glu Thr Glu Thr Glu 
                405                 410                 415     


Pro Glu Glu Asp Thr Ser Glu Gly Glu Glu Ala Glu Asp Gln Ile Leu 
            420                 425                 430         


Ala Asp Pro Ala Glu Glu Gln Arg Cys Gly Asn Gly Asp Pro Ser Arg 
        435                 440                 445             


Tyr Val Ser Asn His Ala Phe Asn Gln Ser Ala Glu Leu Lys Pro His 
    450                 455                 460                 


Val Phe Glu Leu Gly Val Ile Ala Leu Asp Val Ala Glu Arg Glu Ala 
465                 470                 475                 480 


Arg Val Gln Leu Thr Pro Leu Ala Ala Arg Trp Gly Pro Gly Pro Gly 
                485                 490                 495     


Gly Ala Gly Gly Ala Pro Arg Pro Gly Arg Arg Pro Leu Arg Leu Leu 
            500                 505                 510         


Tyr Leu Cys Pro Ala Gly Gly Gly Ala Ala Val Gln Trp Ser Arg Val 
        515                 520                 525             


Glu Glu Gly Val Asn Ala Tyr Trp Phe Arg Gly Leu Arg Pro Gly Thr 
    530                 535                 540                 


Asn Tyr Ser Val Cys Leu Ala Leu Ala Gly Glu Ala Cys His Val Gln 
545                 550                 555                 560 


Val Val Phe Ser Thr Lys Lys Glu Leu Pro Ser 
                565                 570     


<210>  723
<211>  1113
<212>  PRT
<213>  Homo Sapiens

<400>  723

Phe Asn Val Asp Val Lys Asn Ser Met Thr Phe Ser Gly Pro Val Glu 
1               5                   10                  15      


Asp Met Phe Gly Tyr Thr Val Gln Gln Tyr Glu Asn Glu Glu Gly Lys 
            20                  25                  30          


Trp Val Leu Ile Gly Ser Pro Leu Val Gly Gln Pro Lys Asn Arg Thr 
        35                  40                  45              


Gly Asp Val Tyr Lys Cys Pro Val Gly Arg Gly Glu Ser Leu Pro Cys 
    50                  55                  60                  


Val Lys Leu Asp Leu Pro Val Asn Thr Ser Ile Pro Asn Val Thr Glu 
65                  70                  75                  80  


Val Lys Glu Asn Met Thr Phe Gly Ser Thr Leu Val Thr Asn Pro Asn 
                85                  90                  95      


Gly Gly Phe Leu Ala Cys Gly Pro Leu Tyr Ala Tyr Arg Cys Gly His 
            100                 105                 110         


Leu His Tyr Thr Thr Gly Ile Cys Ser Asp Val Ser Pro Thr Phe Gln 
        115                 120                 125             


Val Val Asn Ser Ile Ala Pro Val Gln Glu Cys Ser Thr Gln Leu Asp 
    130                 135                 140                 


Ile Val Ile Val Leu Asp Gly Ser Asn Ser Ile Tyr Pro Trp Asp Ser 
145                 150                 155                 160 


Val Thr Ala Phe Leu Asn Asp Leu Leu Glu Arg Met Asp Ile Gly Pro 
                165                 170                 175     


Lys Gln Thr Gln Val Gly Ile Val Gln Tyr Gly Glu Asn Val Thr His 
            180                 185                 190         


Glu Phe Asn Leu Asn Lys Tyr Ser Ser Thr Glu Glu Val Leu Val Ala 
        195                 200                 205             


Ala Lys Lys Ile Val Gln Arg Gly Gly Arg Gln Thr Met Thr Ala Leu 
    210                 215                 220                 


Gly Ile Asp Thr Ala Arg Lys Glu Ala Phe Thr Glu Ala Arg Gly Ala 
225                 230                 235                 240 


Arg Arg Gly Val Lys Lys Val Met Val Ile Val Thr Asp Gly Glu Ser 
                245                 250                 255     


His Asp Asn His Arg Leu Lys Lys Val Ile Gln Asp Cys Glu Asp Glu 
            260                 265                 270         


Asn Ile Gln Arg Phe Ser Ile Ala Ile Leu Gly Ser Tyr Asn Arg Gly 
        275                 280                 285             


Asn Leu Ser Thr Glu Lys Phe Val Glu Glu Ile Lys Ser Ile Ala Ser 
    290                 295                 300                 


Glu Pro Thr Glu Lys His Phe Phe Asn Val Ser Asp Glu Leu Ala Leu 
305                 310                 315                 320 


Val Thr Ile Val Lys Thr Leu Gly Glu Arg Ile Phe Ala Leu Glu Ala 
                325                 330                 335     


Thr Ala Asp Gln Ser Ala Ala Ser Phe Glu Met Glu Met Ser Gln Thr 
            340                 345                 350         


Gly Phe Ser Ala His Tyr Ser Gln Asp Trp Val Met Leu Gly Ala Val 
        355                 360                 365             


Gly Ala Tyr Asp Trp Asn Gly Thr Val Val Met Gln Lys Ala Ser Gln 
    370                 375                 380                 


Ile Ile Ile Pro Arg Asn Thr Thr Phe Asn Val Glu Ser Thr Lys Lys 
385                 390                 395                 400 


Asn Glu Pro Leu Ala Ser Tyr Leu Gly Tyr Thr Val Asn Ser Ala Thr 
                405                 410                 415     


Ala Ser Ser Gly Asp Val Leu Tyr Ile Ala Gly Gln Pro Arg Tyr Asn 
            420                 425                 430         


His Thr Gly Gln Val Ile Ile Tyr Arg Met Glu Asp Gly Asn Ile Lys 
        435                 440                 445             


Ile Leu Gln Thr Leu Ser Gly Glu Gln Ile Gly Ser Tyr Phe Gly Ser 
    450                 455                 460                 


Ile Leu Thr Thr Thr Asp Ile Asp Lys Asp Ser Asn Thr Asp Ile Leu 
465                 470                 475                 480 


Leu Val Gly Ala Pro Met Tyr Met Gly Thr Glu Lys Glu Glu Gln Gly 
                485                 490                 495     


Lys Val Tyr Val Tyr Ala Leu Asn Gln Thr Arg Phe Glu Tyr Gln Met 
            500                 505                 510         


Ser Leu Glu Pro Ile Lys Gln Thr Cys Cys Ser Ser Arg Gln His Asn 
        515                 520                 525             


Ser Cys Thr Thr Glu Asn Lys Asn Glu Pro Cys Gly Ala Arg Phe Gly 
    530                 535                 540                 


Thr Ala Ile Ala Ala Val Lys Asp Leu Asn Leu Asp Gly Phe Asn Asp 
545                 550                 555                 560 


Ile Val Ile Gly Ala Pro Leu Glu Asp Asp His Gly Gly Ala Val Tyr 
                565                 570                 575     


Ile Tyr His Gly Ser Gly Lys Thr Ile Arg Lys Glu Tyr Ala Gln Arg 
            580                 585                 590         


Ile Pro Ser Gly Gly Asp Gly Lys Thr Leu Lys Phe Phe Gly Gln Ser 
        595                 600                 605             


Ile His Gly Glu Met Asp Leu Asn Gly Asp Gly Leu Thr Asp Val Thr 
    610                 615                 620                 


Ile Gly Gly Leu Gly Gly Ala Ala Leu Phe Trp Ser Arg Asp Val Ala 
625                 630                 635                 640 


Val Val Lys Val Thr Met Asn Phe Glu Pro Asn Lys Val Asn Ile Gln 
                645                 650                 655     


Lys Lys Asn Cys His Met Glu Gly Lys Glu Thr Val Cys Ile Asn Ala 
            660                 665                 670         


Thr Val Cys Phe Asp Val Lys Leu Lys Ser Lys Glu Asp Thr Ile Tyr 
        675                 680                 685             


Glu Ala Asp Leu Gln Tyr Arg Val Thr Leu Asp Ser Leu Arg Gln Ile 
    690                 695                 700                 


Ser Arg Ser Phe Phe Ser Gly Thr Gln Glu Arg Lys Val Gln Arg Asn 
705                 710                 715                 720 


Ile Thr Val Arg Lys Ser Glu Cys Thr Lys His Ser Phe Tyr Met Leu 
                725                 730                 735     


Asp Lys His Asp Phe Gln Asp Ser Val Arg Ile Thr Leu Asp Phe Asn 
            740                 745                 750         


Leu Thr Asp Pro Glu Asn Gly Pro Val Leu Asp Asp Ser Leu Pro Asn 
        755                 760                 765             


Ser Val His Glu Tyr Ile Pro Phe Ala Lys Asp Cys Gly Asn Lys Glu 
    770                 775                 780                 


Lys Cys Ile Ser Asp Leu Ser Leu His Val Ala Thr Thr Glu Lys Asp 
785                 790                 795                 800 


Leu Leu Ile Val Arg Ser Gln Asn Asp Lys Phe Asn Val Ser Leu Thr 
                805                 810                 815     


Val Lys Asn Thr Lys Asp Ser Ala Tyr Asn Thr Arg Thr Ile Val His 
            820                 825                 830         


Tyr Ser Pro Asn Leu Val Phe Ser Gly Ile Glu Ala Ile Gln Lys Asp 
        835                 840                 845             


Ser Cys Glu Ser Asn His Asn Ile Thr Cys Lys Val Gly Tyr Pro Phe 
    850                 855                 860                 


Leu Arg Arg Gly Glu Met Val Thr Phe Lys Ile Leu Phe Gln Phe Asn 
865                 870                 875                 880 


Thr Ser Tyr Leu Met Glu Asn Val Thr Ile Tyr Leu Ser Ala Thr Ser 
                885                 890                 895     


Asp Ser Glu Glu Pro Pro Glu Thr Leu Ser Asp Asn Val Val Asn Ile 
            900                 905                 910         


Ser Ile Pro Val Lys Tyr Glu Val Gly Leu Gln Phe Tyr Ser Ser Ala 
        915                 920                 925             


Ser Glu Tyr His Ile Ser Ile Ala Ala Asn Glu Thr Val Pro Glu Val 
    930                 935                 940                 


Ile Asn Ser Thr Glu Asp Ile Gly Asn Glu Ile Asn Ile Phe Tyr Leu 
945                 950                 955                 960 


Ile Arg Lys Ser Gly Ser Phe Pro Met Pro Glu Leu Lys Leu Ser Ile 
                965                 970                 975     


Ser Phe Pro Asn Met Thr Ser Asn Gly Tyr Pro Val Leu Tyr Pro Thr 
            980                 985                 990         


Gly Leu Ser Ser Ser Glu Asn Ala  Asn Cys Arg Pro His  Ile Phe Glu 
        995                 1000                 1005             


Asp Pro  Phe Ser Ile Asn Ser  Gly Lys Lys Met Thr  Thr Ser Thr 
    1010                 1015                 1020             


Asp His  Leu Lys Arg Gly Thr  Ile Leu Asp Cys Asn  Thr Cys Lys 
    1025                 1030                 1035             


Phe Ala  Thr Ile Thr Cys Asn  Leu Thr Ser Ser Asp  Ile Ser Gln 
    1040                 1045                 1050             


Val Asn  Val Ser Leu Ile Leu  Trp Lys Pro Thr Phe  Ile Lys Ser 
    1055                 1060                 1065             


Tyr Phe  Ser Ser Leu Asn Leu  Thr Ile Arg Gly Glu  Leu Arg Ser 
    1070                 1075                 1080             


Glu Asn  Ala Ser Leu Val Leu  Ser Ser Ser Asn Gln  Lys Arg Glu 
    1085                 1090                 1095             


Leu Ala  Ile Gln Ile Ser Lys  Asp Gly Leu Pro Gly  Arg Val Pro 
    1100                 1105                 1110             


<210>  724
<211>  1103
<212>  PRT
<213>  Homo Sapiens

<400>  724

Tyr Asn Val Gly Leu Pro Glu Ala Lys Ile Phe Ser Gly Pro Ser Ser 
1               5                   10                  15      


Glu Gln Phe Gly Tyr Ala Val Gln Gln Phe Ile Asn Pro Lys Gly Asn 
            20                  25                  30          


Trp Leu Leu Val Gly Ser Pro Trp Ser Gly Phe Pro Glu Asn Arg Met 
        35                  40                  45              


Gly Asp Val Tyr Lys Cys Pro Val Asp Leu Ser Thr Ala Thr Cys Glu 
    50                  55                  60                  


Lys Leu Asn Leu Gln Thr Ser Thr Ser Ile Pro Asn Val Thr Glu Met 
65                  70                  75                  80  


Lys Thr Asn Met Ser Leu Gly Leu Ile Leu Thr Arg Asn Met Gly Thr 
                85                  90                  95      


Gly Gly Phe Leu Thr Cys Gly Pro Leu Trp Ala Gln Gln Cys Gly Asn 
            100                 105                 110         


Gln Tyr Tyr Thr Thr Gly Val Cys Ser Asp Ile Ser Pro Asp Phe Gln 
        115                 120                 125             


Leu Ser Ala Ser Phe Ser Pro Ala Thr Gln Pro Cys Pro Ser Leu Ile 
    130                 135                 140                 


Asp Val Val Val Val Cys Asp Glu Ser Asn Ser Ile Tyr Pro Trp Asp 
145                 150                 155                 160 


Ala Val Lys Asn Phe Leu Glu Lys Phe Val Gln Gly Leu Asp Ile Gly 
                165                 170                 175     


Pro Thr Lys Thr Gln Val Gly Leu Ile Gln Tyr Ala Asn Asn Pro Arg 
            180                 185                 190         


Val Val Phe Asn Leu Asn Thr Tyr Lys Thr Lys Glu Glu Met Ile Val 
        195                 200                 205             


Ala Thr Ser Gln Thr Ser Gln Tyr Gly Gly Asp Leu Thr Asn Thr Phe 
    210                 215                 220                 


Gly Ala Ile Gln Tyr Ala Arg Lys Tyr Ala Tyr Ser Ala Ala Ser Gly 
225                 230                 235                 240 


Gly Arg Arg Ser Ala Thr Lys Val Met Val Val Val Thr Asp Gly Glu 
                245                 250                 255     


Ser His Asp Gly Ser Met Leu Lys Ala Val Ile Asp Gln Cys Asn His 
            260                 265                 270         


Asp Asn Ile Leu Arg Phe Gly Ile Ala Val Leu Gly Tyr Leu Asn Arg 
        275                 280                 285             


Asn Ala Leu Asp Thr Lys Asn Leu Ile Lys Glu Ile Lys Ala Ile Ala 
    290                 295                 300                 


Ser Ile Pro Thr Glu Arg Tyr Phe Phe Asn Val Ser Asp Glu Ala Ala 
305                 310                 315                 320 


Leu Leu Glu Lys Ala Gly Thr Leu Gly Glu Gln Ile Phe Ser Ile Glu 
                325                 330                 335     


Gly Thr Val Gln Gly Gly Asp Asn Phe Gln Met Glu Met Ser Gln Val 
            340                 345                 350         


Gly Phe Ser Ala Asp Tyr Ser Ser Gln Asn Asp Ile Leu Met Leu Gly 
        355                 360                 365             


Ala Val Gly Ala Phe Gly Trp Ser Gly Thr Ile Val Gln Lys Thr Ser 
    370                 375                 380                 


His Gly His Leu Ile Phe Pro Lys Gln Ala Phe Asp Gln Ile Leu Gln 
385                 390                 395                 400 


Asp Arg Asn His Ser Ser Tyr Leu Gly Tyr Ser Val Ala Ala Ile Ser 
                405                 410                 415     


Thr Gly Glu Ser Thr His Phe Val Ala Gly Ala Pro Arg Ala Asn Tyr 
            420                 425                 430         


Thr Gly Gln Ile Val Leu Tyr Ser Val Asn Glu Asn Gly Asn Ile Thr 
        435                 440                 445             


Val Ile Gln Ala His Arg Gly Asp Gln Ile Gly Ser Tyr Phe Gly Ser 
    450                 455                 460                 


Val Leu Cys Ser Val Asp Val Asp Lys Asp Thr Ile Thr Asp Val Leu 
465                 470                 475                 480 


Leu Val Gly Ala Pro Met Tyr Met Ser Asp Leu Lys Lys Glu Glu Gly 
                485                 490                 495     


Arg Val Tyr Leu Phe Thr Ile Lys Glu Gly Ile Leu Gly Gln His Gln 
            500                 505                 510         


Phe Leu Glu Gly Pro Glu Gly Ile Glu Asn Thr Arg Phe Gly Ser Ala 
        515                 520                 525             


Ile Ala Ala Leu Ser Asp Ile Asn Met Asp Gly Phe Asn Asp Val Ile 
    530                 535                 540                 


Val Gly Ser Pro Leu Glu Asn Gln Asn Ser Gly Ala Val Tyr Ile Tyr 
545                 550                 555                 560 


Asn Gly His Gln Gly Thr Ile Arg Thr Lys Tyr Ser Gln Lys Ile Leu 
                565                 570                 575     


Gly Ser Asp Gly Ala Phe Arg Ser His Leu Gln Tyr Phe Gly Arg Ser 
            580                 585                 590         


Leu Asp Gly Tyr Gly Asp Leu Asn Gly Asp Ser Ile Thr Asp Val Ser 
        595                 600                 605             


Ile Gly Ala Phe Gly Gln Val Val Gln Leu Trp Ser Gln Ser Ile Ala 
    610                 615                 620                 


Asp Val Ala Ile Glu Ala Ser Phe Thr Pro Glu Lys Ile Thr Leu Val 
625                 630                 635                 640 


Asn Lys Asn Ala Gln Ile Ile Leu Lys Leu Cys Phe Ser Ala Lys Phe 
                645                 650                 655     


Arg Pro Thr Lys Gln Asn Asn Gln Val Ala Ile Val Tyr Asn Ile Thr 
            660                 665                 670         


Leu Asp Ala Asp Gly Phe Ser Ser Arg Val Thr Ser Arg Gly Leu Phe 
        675                 680                 685             


Lys Glu Asn Asn Glu Arg Cys Leu Gln Lys Asn Met Val Val Asn Gln 
    690                 695                 700                 


Ala Gln Ser Cys Pro Glu His Ile Ile Tyr Ile Gln Glu Pro Ser Asp 
705                 710                 715                 720 


Val Val Asn Ser Leu Asp Leu Arg Val Asp Ile Ser Leu Glu Asn Pro 
                725                 730                 735     


Gly Thr Ser Pro Ala Leu Glu Ala Tyr Ser Glu Thr Ala Lys Val Phe 
            740                 745                 750         


Ser Ile Pro Phe His Lys Asp Cys Gly Glu Asp Gly Leu Cys Ile Ser 
        755                 760                 765             


Asp Leu Val Leu Asp Val Arg Gln Ile Pro Ala Ala Gln Glu Gln Pro 
    770                 775                 780                 


Phe Ile Val Ser Asn Gln Asn Lys Arg Leu Thr Phe Ser Val Thr Leu 
785                 790                 795                 800 


Lys Asn Lys Arg Glu Ser Ala Tyr Asn Thr Gly Ile Val Val Asp Phe 
                805                 810                 815     


Ser Glu Asn Leu Phe Phe Ala Ser Phe Ser Leu Pro Val Asp Gly Thr 
            820                 825                 830         


Glu Val Thr Cys Gln Val Ala Ala Ser Gln Lys Ser Val Ala Cys Asp 
        835                 840                 845             


Val Gly Tyr Pro Ala Leu Lys Arg Glu Gln Gln Val Thr Phe Thr Ile 
    850                 855                 860                 


Asn Phe Asp Phe Asn Leu Gln Asn Leu Gln Asn Gln Ala Ser Leu Ser 
865                 870                 875                 880 


Phe Gln Ala Leu Ser Glu Ser Gln Glu Glu Asn Lys Ala Asp Asn Leu 
                885                 890                 895     


Val Asn Leu Lys Ile Pro Leu Leu Tyr Asp Ala Glu Ile His Leu Thr 
            900                 905                 910         


Arg Ser Thr Asn Ile Asn Phe Tyr Glu Ile Ser Ser Asp Gly Asn Val 
        915                 920                 925             


Pro Ser Ile Val His Ser Phe Glu Asp Val Gly Pro Lys Phe Ile Phe 
    930                 935                 940                 


Ser Leu Lys Val Thr Thr Gly Ser Val Pro Val Ser Met Ala Thr Val 
945                 950                 955                 960 


Ile Ile His Ile Pro Gln Tyr Thr Lys Glu Lys Asn Pro Leu Met Tyr 
                965                 970                 975     


Leu Thr Gly Val Gln Thr Asp Lys Ala Gly Asp Ile Ser Cys Asn Ala 
            980                 985                 990         


Asp Ile Asn Pro Leu Lys Ile Gly  Gln Thr Ser Ser Ser  Val Ser Phe 
        995                 1000                 1005             


Lys Ser  Glu Asn Phe Arg His  Thr Lys Glu Leu Asn  Cys Arg Thr 
    1010                 1015                 1020             


Ala Ser  Cys Ser Asn Val Thr  Cys Trp Leu Lys Asp  Val His Met 
    1025                 1030                 1035             


Lys Gly  Glu Tyr Phe Val Asn  Val Thr Thr Arg Ile  Trp Asn Gly 
    1040                 1045                 1050             


Thr Phe  Ala Ser Ser Thr Phe  Gln Thr Val Gln Leu  Thr Ala Ala 
    1055                 1060                 1065             


Ala Glu  Ile Asn Thr Tyr Asn  Pro Glu Ile Tyr Val  Ile Glu Asp 
    1070                 1075                 1080             


Asn Thr  Val Thr Ile Pro Leu  Met Ile Met Lys Pro  Asp Glu Lys 
    1085                 1090                 1095             


Ala Glu  Val Pro Thr 
    1100             


<210>  725
<211>  962
<212>  PRT
<213>  Homo Sapiens

<400>  725

Leu Asn Leu Asp Pro Val Gln Leu Thr Phe Tyr Ala Gly Pro Asn Gly 
1               5                   10                  15      


Ser Gln Phe Gly Phe Ser Leu Asp Phe His Lys Asp Ser His Gly Arg 
            20                  25                  30          


Val Ala Ile Val Val Gly Ala Pro Arg Thr Leu Gly Pro Ser Gln Glu 
        35                  40                  45              


Glu Thr Gly Gly Val Phe Leu Cys Pro Trp Arg Ala Glu Gly Gly Gln 
    50                  55                  60                  


Cys Pro Ser Leu Leu Phe Asp Leu Arg Asp Glu Thr Arg Asn Val Gly 
65                  70                  75                  80  


Ser Gln Thr Leu Gln Thr Phe Lys Ala Arg Gln Gly Leu Gly Ala Ser 
                85                  90                  95      


Val Val Ser Trp Ser Asp Val Ile Val Ala Cys Ala Pro Trp Gln His 
            100                 105                 110         


Trp Asn Val Leu Glu Lys Thr Glu Glu Ala Glu Lys Thr Pro Val Gly 
        115                 120                 125             


Ser Cys Phe Leu Ala Gln Pro Glu Ser Gly Arg Arg Ala Glu Tyr Ser 
    130                 135                 140                 


Pro Cys Arg Gly Asn Thr Leu Ser Arg Ile Tyr Val Glu Asn Asp Phe 
145                 150                 155                 160 


Ser Trp Asp Lys Arg Tyr Cys Glu Ala Gly Phe Ser Ser Val Val Thr 
                165                 170                 175     


Gln Ala Gly Glu Leu Val Leu Gly Ala Pro Gly Gly Tyr Tyr Phe Leu 
            180                 185                 190         


Gly Leu Leu Ala Gln Ala Pro Val Ala Asp Ile Phe Ser Ser Tyr Arg 
        195                 200                 205             


Pro Gly Ile Leu Leu Trp His Val Ser Ser Gln Ser Leu Ser Phe Asp 
    210                 215                 220                 


Ser Ser Asn Pro Glu Tyr Phe Asp Gly Tyr Trp Gly Tyr Ser Val Ala 
225                 230                 235                 240 


Val Gly Glu Phe Asp Gly Asp Leu Asn Thr Thr Glu Tyr Val Val Gly 
                245                 250                 255     


Ala Pro Thr Trp Ser Trp Thr Leu Gly Ala Val Glu Ile Leu Asp Ser 
            260                 265                 270         


Tyr Tyr Gln Arg Leu His Arg Leu Arg Gly Glu Gln Met Ala Ser Tyr 
        275                 280                 285             


Phe Gly His Ser Val Ala Val Thr Asp Val Asn Gly Asp Gly Arg His 
    290                 295                 300                 


Asp Leu Leu Val Gly Ala Pro Leu Tyr Met Glu Ser Arg Ala Asp Arg 
305                 310                 315                 320 


Lys Leu Ala Glu Val Gly Arg Val Tyr Leu Phe Leu Gln Pro Arg Gly 
                325                 330                 335     


Pro His Ala Leu Gly Ala Pro Ser Leu Leu Leu Thr Gly Thr Gln Leu 
            340                 345                 350         


Tyr Gly Arg Phe Gly Ser Ala Ile Ala Pro Leu Gly Asp Leu Asp Arg 
        355                 360                 365             


Asp Gly Tyr Asn Asp Ile Ala Val Ala Ala Pro Tyr Gly Gly Pro Ser 
    370                 375                 380                 


Gly Arg Gly Gln Val Leu Val Phe Leu Gly Gln Ser Glu Gly Leu Arg 
385                 390                 395                 400 


Ser Arg Pro Ser Gln Val Leu Asp Ser Pro Phe Pro Thr Gly Ser Ala 
                405                 410                 415     


Phe Gly Phe Ser Leu Arg Gly Ala Val Asp Ile Asp Asp Asn Gly Tyr 
            420                 425                 430         


Pro Asp Leu Ile Val Gly Ala Tyr Gly Ala Asn Gln Val Ala Val Tyr 
        435                 440                 445             


Arg Ala Gln Pro Val Val Lys Ala Ser Val Gln Leu Leu Val Gln Asp 
    450                 455                 460                 


Ser Leu Asn Pro Ala Val Lys Ser Cys Val Leu Pro Gln Thr Lys Thr 
465                 470                 475                 480 


Pro Val Ser Cys Phe Asn Ile Gln Met Cys Val Gly Ala Thr Gly His 
                485                 490                 495     


Asn Ile Pro Gln Lys Leu Ser Leu Asn Ala Glu Leu Gln Leu Asp Arg 
            500                 505                 510         


Gln Lys Pro Arg Gln Gly Arg Arg Val Leu Leu Leu Gly Ser Gln Gln 
        515                 520                 525             


Ala Gly Thr Thr Leu Asn Leu Asp Leu Gly Gly Lys His Ser Pro Ile 
    530                 535                 540                 


Cys His Thr Thr Met Ala Phe Leu Arg Asp Glu Ala Asp Phe Arg Asp 
545                 550                 555                 560 


Lys Leu Ser Pro Ile Val Leu Ser Leu Asn Val Ser Leu Pro Pro Thr 
                565                 570                 575     


Glu Ala Gly Met Ala Pro Ala Val Val Leu His Gly Asp Thr His Val 
            580                 585                 590         


Gln Glu Gln Thr Arg Ile Val Leu Asp Cys Gly Glu Asp Asp Val Cys 
        595                 600                 605             


Val Pro Gln Leu Gln Leu Thr Ala Ser Val Thr Gly Ser Pro Leu Leu 
    610                 615                 620                 


Val Gly Ala Asp Asn Val Leu Glu Leu Gln Met Asp Ala Ala Asn Glu 
625                 630                 635                 640 


Gly Glu Gly Ala Tyr Glu Ala Glu Leu Ala Val His Leu Pro Gln Gly 
                645                 650                 655     


Ala His Tyr Met Arg Ala Leu Ser Asn Val Glu Gly Phe Glu Arg Leu 
            660                 665                 670         


Ile Cys Asn Gln Lys Lys Glu Asn Glu Thr Arg Val Val Leu Cys Glu 
        675                 680                 685             


Leu Gly Asn Pro Met Lys Lys Asn Ala Gln Ile Gly Ile Ala Met Leu 
    690                 695                 700                 


Val Ser Val Gly Asn Leu Glu Glu Ala Gly Glu Ser Val Ser Phe Gln 
705                 710                 715                 720 


Leu Gln Ile Arg Ser Lys Asn Ser Gln Asn Pro Asn Ser Lys Ile Val 
                725                 730                 735     


Leu Leu Asp Val Pro Val Arg Ala Glu Ala Gln Val Glu Leu Arg Gly 
            740                 745                 750         


Asn Ser Phe Pro Ala Ser Leu Val Val Ala Ala Glu Glu Gly Glu Arg 
        755                 760                 765             


Glu Gln Asn Ser Leu Asp Ser Trp Gly Pro Lys Val Glu His Thr Tyr 
    770                 775                 780                 


Glu Leu His Asn Asn Gly Pro Gly Thr Val Asn Gly Leu His Leu Ser 
785                 790                 795                 800 


Ile His Leu Pro Gly Gln Ser Gln Pro Ser Asp Leu Leu Tyr Ile Leu 
                805                 810                 815     


Asp Ile Gln Pro Gln Gly Gly Leu Gln Cys Phe Pro Gln Pro Pro Val 
            820                 825                 830         


Asn Pro Leu Lys Val Asp Trp Gly Leu Pro Ile Pro Ser Pro Ser Pro 
        835                 840                 845             


Ile His Pro Ala His His Lys Arg Asp Arg Arg Gln Ile Phe Leu Pro 
    850                 855                 860                 


Glu Pro Glu Gln Pro Ser Arg Leu Gln Asp Pro Val Leu Val Ser Cys 
865                 870                 875                 880 


Asp Ser Ala Pro Cys Thr Val Val Gln Cys Asp Leu Gln Glu Met Ala 
                885                 890                 895     


Arg Gly Gln Arg Ala Met Val Thr Val Leu Ala Phe Leu Trp Leu Pro 
            900                 905                 910         


Ser Leu Tyr Gln Arg Pro Leu Asp Gln Phe Val Leu Gln Ser His Ala 
        915                 920                 925             


Trp Phe Asn Val Ser Ser Leu Pro Tyr Ala Val Pro Pro Leu Ser Leu 
    930                 935                 940                 


Pro Arg Gly Glu Ala Gln Val Trp Thr Gln Leu Leu Arg Ala Leu Glu 
945                 950                 955                 960 


Glu Arg 
        


<210>  726
<211>  959
<212>  PRT
<213>  Homo Sapiens

<400>  726

Phe Asn Leu Asp Thr Arg Phe Leu Val Val Lys Glu Ala Gly Asn Pro 
1               5                   10                  15      


Gly Ser Leu Phe Gly Tyr Ser Val Ala Leu His Arg Gln Thr Glu Arg 
            20                  25                  30          


Gln Gln Arg Tyr Leu Leu Leu Ala Gly Ala Pro Arg Glu Leu Ala Val 
        35                  40                  45              


Pro Asp Gly Tyr Thr Asn Arg Thr Gly Ala Val Tyr Leu Cys Pro Leu 
    50                  55                  60                  


Thr Ala His Lys Asp Asp Cys Glu Arg Met Asn Ile Thr Val Lys Asn 
65                  70                  75                  80  


Asp Pro Gly His His Ile Ile Glu Asp Met Trp Leu Gly Val Thr Val 
                85                  90                  95      


Ala Ser Gln Gly Pro Ala Gly Arg Val Leu Val Cys Ala His Arg Tyr 
            100                 105                 110         


Thr Gln Val Leu Trp Ser Gly Ser Glu Asp Gln Arg Arg Met Val Gly 
        115                 120                 125             


Lys Cys Tyr Val Arg Gly Asn Asp Leu Glu Leu Asp Ser Ser Asp Asp 
    130                 135                 140                 


Trp Gln Thr Tyr His Asn Glu Met Cys Asn Ser Asn Thr Asp Tyr Leu 
145                 150                 155                 160 


Glu Thr Gly Met Cys Gln Leu Gly Thr Ser Gly Gly Phe Thr Gln Asn 
                165                 170                 175     


Thr Val Tyr Phe Gly Ala Pro Gly Ala Tyr Asn Trp Lys Gly Asn Ser 
            180                 185                 190         


Tyr Met Ile Gln Arg Lys Glu Trp Asp Leu Ser Glu Tyr Ser Tyr Lys 
        195                 200                 205             


Asp Pro Glu Asp Gln Gly Asn Leu Tyr Ile Gly Tyr Thr Met Gln Val 
    210                 215                 220                 


Gly Ser Phe Ile Leu His Pro Lys Asn Ile Thr Ile Val Thr Gly Ala 
225                 230                 235                 240 


Pro Arg His Arg His Met Gly Ala Val Phe Leu Leu Ser Gln Glu Ala 
                245                 250                 255     


Gly Gly Asp Leu Arg Arg Arg Gln Val Leu Glu Gly Ser Gln Val Gly 
            260                 265                 270         


Ala Tyr Phe Gly Ser Ala Ile Ala Leu Ala Asp Leu Asn Asn Asp Gly 
        275                 280                 285             


Trp Gln Asp Leu Leu Val Gly Ala Pro Tyr Tyr Phe Glu Arg Lys Glu 
    290                 295                 300                 


Glu Val Gly Gly Ala Ile Tyr Val Phe Met Asn Gln Ala Gly Thr Ser 
305                 310                 315                 320 


Phe Pro Ala His Pro Ser Leu Leu Leu His Gly Pro Ser Gly Ser Ala 
                325                 330                 335     


Phe Gly Leu Ser Val Ala Ser Ile Gly Asp Ile Asn Gln Asp Gly Phe 
            340                 345                 350         


Gln Asp Ile Ala Val Gly Ala Pro Phe Glu Gly Leu Gly Lys Val Tyr 
        355                 360                 365             


Ile Tyr His Ser Ser Ser Lys Gly Leu Leu Arg Gln Pro Gln Gln Val 
    370                 375                 380                 


Ile His Gly Glu Lys Leu Gly Leu Pro Gly Leu Ala Thr Phe Gly Tyr 
385                 390                 395                 400 


Ser Leu Ser Gly Gln Met Asp Val Asp Glu Asn Phe Tyr Pro Asp Leu 
                405                 410                 415     


Leu Val Gly Ser Leu Ser Asp His Ile Val Leu Leu Arg Ala Arg Pro 
            420                 425                 430         


Val Ile Asn Ile Val His Lys Thr Leu Val Pro Arg Pro Ala Val Leu 
        435                 440                 445             


Asp Pro Ala Leu Cys Thr Ala Thr Ser Cys Val Gln Val Glu Leu Cys 
    450                 455                 460                 


Phe Ala Tyr Asn Gln Ser Ala Gly Asn Pro Asn Tyr Arg Arg Asn Ile 
465                 470                 475                 480 


Thr Leu Ala Tyr Thr Leu Glu Ala Asp Arg Asp Arg Arg Pro Pro Arg 
                485                 490                 495     


Phe Arg Phe Ala Gly Ser Glu Ser Ala Val Phe His Gly Phe Phe Ser 
            500                 505                 510         


Met Pro Glu Met Arg Cys Gln Lys Leu Glu Leu Leu Leu Met Asp Asn 
        515                 520                 525             


Leu Arg Asp Lys Leu Arg Pro Ile Ile Ile Ser Met Asn Tyr Ser Leu 
    530                 535                 540                 


Pro Leu Arg Met Pro Asp Arg Pro Arg Leu Gly Leu Arg Ser Leu Asp 
545                 550                 555                 560 


Ala Tyr Pro Ile Leu Asn Gln Ala Gln Ala Leu Glu Asn His Thr Glu 
                565                 570                 575     


Val Gln Phe Gln Lys Glu Cys Gly Pro Asp Asn Lys Cys Glu Ser Asn 
            580                 585                 590         


Leu Gln Met Arg Ala Ala Phe Val Ser Glu Gln Gln Gln Lys Leu Ser 
        595                 600                 605             


Arg Leu Gln Tyr Ser Arg Asp Val Arg Lys Leu Leu Leu Ser Ile Asn 
    610                 615                 620                 


Val Thr Asn Thr Arg Thr Ser Glu Arg Ser Gly Glu Asp Ala His Glu 
625                 630                 635                 640 


Ala Leu Leu Thr Leu Val Val Pro Pro Ala Leu Leu Leu Ser Ser Val 
                645                 650                 655     


Arg Pro Pro Gly Ala Cys Gln Ala Asn Glu Thr Ile Phe Cys Glu Leu 
            660                 665                 670         


Gly Asn Pro Phe Lys Arg Asn Gln Arg Met Glu Leu Leu Ile Ala Phe 
        675                 680                 685             


Glu Val Ile Gly Val Thr Leu His Thr Arg Asp Leu Gln Val Gln Leu 
    690                 695                 700                 


Gln Leu Ser Thr Ser Ser His Gln Asp Asn Leu Trp Pro Met Ile Leu 
705                 710                 715                 720 


Thr Leu Leu Val Asp Tyr Thr Leu Gln Thr Ser Leu Ser Met Val Asn 
                725                 730                 735     


His Arg Leu Gln Ser Phe Phe Gly Gly Thr Val Met Gly Glu Ser Gly 
            740                 745                 750         


Met Lys Thr Val Glu Asp Val Gly Ser Pro Leu Lys Tyr Glu Phe Gln 
        755                 760                 765             


Val Gly Pro Met Gly Glu Gly Leu Val Gly Leu Gly Thr Leu Val Leu 
    770                 775                 780                 


Gly Leu Glu Trp Pro Tyr Glu Val Ser Asn Gly Lys Trp Leu Leu Tyr 
785                 790                 795                 800 


Pro Thr Glu Ile Thr Val His Gly Asn Gly Ser Trp Pro Cys Arg Pro 
                805                 810                 815     


Pro Gly Asp Leu Ile Asn Pro Leu Asn Leu Thr Leu Ser Asp Pro Gly 
            820                 825                 830         


Asp Arg Pro Ser Ser Pro Gln Arg Arg Arg Arg Gln Leu Asp Pro Gly 
        835                 840                 845             


Gly Gly Gln Gly Pro Pro Pro Val Thr Leu Ala Ala Ala Lys Lys Ala 
    850                 855                 860                 


Lys Ser Glu Thr Val Leu Thr Cys Ala Thr Gly Arg Ala His Cys Val 
865                 870                 875                 880 


Trp Leu Glu Cys Pro Ile Pro Asp Ala Pro Val Val Thr Asn Val Thr 
                885                 890                 895     


Val Lys Ala Arg Val Trp Asn Ser Thr Phe Ile Glu Asp Tyr Arg Asp 
            900                 905                 910         


Phe Asp Arg Val Arg Val Asn Gly Trp Ala Thr Leu Phe Leu Arg Thr 
        915                 920                 925             


Ser Ile Pro Thr Ile Asn Met Glu Asn Lys Thr Thr Trp Phe Ser Val 
    930                 935                 940                 


Asp Ile Asp Ser Glu Leu Val Glu Glu Leu Pro Ala Glu Ile Glu 
945                 950                 955                 


<210>  727
<211>  943
<212>  PRT
<213>  Homo Sapiens

<400>  727

Asn Val Asp Thr Glu Ser Ala Leu Leu Tyr Gln Gly Pro His Asn Thr 
1               5                   10                  15      


Leu Phe Gly Tyr Ser Val Val Leu His Ser His Gly Ala Asn Arg Trp 
            20                  25                  30          


Leu Leu Val Gly Ala Pro Thr Ala Asn Trp Leu Ala Asn Ala Ser Val 
        35                  40                  45              


Ile Asn Pro Gly Ala Ile Tyr Arg Cys Arg Ile Gly Lys Asn Pro Gly 
    50                  55                  60                  


Gln Thr Cys Glu Gln Leu Gln Leu Gly Ser Pro Asn Gly Glu Pro Cys 
65                  70                  75                  80  


Gly Lys Thr Cys Leu Glu Glu Arg Asp Asn Gln Trp Leu Gly Val Thr 
                85                  90                  95      


Leu Ser Arg Gln Pro Gly Glu Asn Gly Ser Ile Val Thr Cys Gly His 
            100                 105                 110         


Arg Trp Lys Asn Ile Phe Tyr Ile Lys Asn Glu Asn Lys Leu Pro Thr 
        115                 120                 125             


Gly Gly Cys Tyr Gly Val Pro Pro Asp Leu Arg Thr Glu Leu Ser Lys 
    130                 135                 140                 


Arg Ile Ala Pro Cys Tyr Gln Asp Tyr Val Lys Lys Phe Gly Glu Asn 
145                 150                 155                 160 


Phe Ala Ser Cys Gln Ala Gly Ile Ser Ser Phe Tyr Thr Lys Asp Leu 
                165                 170                 175     


Ile Val Met Gly Ala Pro Gly Ser Ser Tyr Trp Thr Gly Ser Leu Phe 
            180                 185                 190         


Val Tyr Asn Ile Thr Thr Asn Lys Tyr Lys Ala Phe Leu Asp Lys Gln 
        195                 200                 205             


Asn Gln Val Lys Phe Gly Ser Tyr Leu Gly Tyr Ser Val Gly Ala Gly 
    210                 215                 220                 


His Phe Arg Ser Gln His Thr Thr Glu Val Val Gly Gly Ala Pro Gln 
225                 230                 235                 240 


His Glu Gln Ile Gly Lys Ala Tyr Ile Phe Ser Ile Asp Glu Lys Glu 
                245                 250                 255     


Leu Asn Ile Leu His Glu Met Lys Gly Lys Lys Leu Gly Ser Tyr Phe 
            260                 265                 270         


Gly Ala Ser Val Cys Ala Val Asp Leu Asn Ala Asp Gly Phe Ser Asp 
        275                 280                 285             


Leu Leu Val Gly Ala Pro Met Gln Ser Thr Ile Arg Glu Glu Gly Arg 
    290                 295                 300                 


Val Phe Val Tyr Ile Asn Ser Gly Ser Gly Ala Val Met Asn Ala Met 
305                 310                 315                 320 


Glu Thr Asn Leu Val Gly Ser Asp Lys Tyr Ala Ala Arg Phe Gly Glu 
                325                 330                 335     


Ser Ile Val Asn Leu Gly Asp Ile Asp Asn Asp Gly Phe Glu Asp Val 
            340                 345                 350         


Ala Ile Gly Ala Pro Gln Glu Asp Asp Leu Gln Gly Ala Ile Tyr Ile 
        355                 360                 365             


Tyr Asn Gly Arg Ala Asp Gly Ile Ser Ser Thr Phe Ser Gln Arg Ile 
    370                 375                 380                 


Glu Gly Leu Gln Ile Ser Lys Ser Leu Ser Met Phe Gly Gln Ser Ile 
385                 390                 395                 400 


Ser Gly Gln Ile Asp Ala Asp Asn Asn Gly Tyr Val Asp Val Ala Val 
                405                 410                 415     


Gly Ala Phe Arg Ser Asp Ser Ala Val Leu Leu Arg Thr Arg Pro Val 
            420                 425                 430         


Val Ile Val Asp Ala Ser Leu Ser His Pro Glu Ser Val Asn Arg Thr 
        435                 440                 445             


Lys Phe Asp Cys Val Glu Asn Gly Trp Pro Ser Val Cys Ile Asp Leu 
    450                 455                 460                 


Thr Leu Cys Phe Ser Tyr Lys Gly Lys Glu Val Pro Gly Tyr Ile Val 
465                 470                 475                 480 


Leu Phe Tyr Asn Met Ser Leu Asp Val Asn Arg Lys Ala Glu Ser Pro 
                485                 490                 495     


Pro Arg Phe Tyr Phe Ser Ser Asn Gly Thr Ser Asp Val Ile Thr Gly 
            500                 505                 510         


Ser Ile Gln Val Ser Ser Arg Glu Ala Asn Cys Arg Thr His Gln Ala 
        515                 520                 525             


Phe Met Arg Lys Asp Val Arg Asp Ile Leu Thr Pro Ile Gln Ile Glu 
    530                 535                 540                 


Ala Ala Tyr His Leu Gly Pro His Val Ile Ser Lys Arg Ser Thr Glu 
545                 550                 555                 560 


Glu Phe Pro Pro Leu Gln Pro Ile Leu Gln Gln Lys Lys Glu Lys Asp 
                565                 570                 575     


Ile Met Lys Lys Thr Ile Asn Phe Ala Arg Phe Cys Ala His Glu Asn 
            580                 585                 590         


Cys Ser Ala Asp Leu Gln Val Ser Ala Lys Ile Gly Phe Leu Lys Pro 
        595                 600                 605             


His Glu Asn Lys Thr Tyr Leu Ala Val Gly Ser Met Lys Thr Leu Met 
    610                 615                 620                 


Leu Asn Val Ser Leu Phe Asn Ala Gly Asp Asp Ala Tyr Glu Thr Thr 
625                 630                 635                 640 


Leu His Val Lys Leu Pro Val Gly Leu Tyr Phe Ile Lys Ile Leu Glu 
                645                 650                 655     


Leu Glu Glu Lys Gln Ile Asn Cys Glu Val Thr Asp Asn Ser Gly Val 
            660                 665                 670         


Val Gln Leu Asp Cys Ser Ile Gly Tyr Ile Tyr Val Asp His Leu Ser 
        675                 680                 685             


Arg Ile Asp Ile Ser Phe Leu Leu Asp Val Ser Ser Leu Ser Arg Ala 
    690                 695                 700                 


Glu Glu Asp Leu Ser Ile Thr Val His Ala Thr Cys Glu Asn Glu Glu 
705                 710                 715                 720 


Glu Met Asp Asn Leu Lys His Ser Arg Val Thr Val Ala Ile Pro Leu 
                725                 730                 735     


Lys Tyr Glu Val Lys Leu Thr Val His Gly Phe Val Asn Pro Thr Ser 
            740                 745                 750         


Phe Val Tyr Gly Ser Asn Asp Glu Asn Glu Pro Glu Thr Cys Met Val 
        755                 760                 765             


Glu Lys Met Asn Leu Thr Phe His Val Ile Asn Thr Gly Asn Ser Met 
    770                 775                 780                 


Ala Pro Asn Val Ser Val Glu Ile Met Val Pro Asn Ser Phe Ser Pro 
785                 790                 795                 800 


Gln Thr Asp Lys Leu Phe Asn Ile Leu Asp Val Gln Thr Thr Thr Gly 
                805                 810                 815     


Glu Cys His Phe Glu Asn Tyr Gln Arg Val Cys Ala Leu Glu Gln Gln 
            820                 825                 830         


Lys Ser Ala Met Gln Thr Leu Lys Gly Ile Val Arg Phe Leu Ser Lys 
        835                 840                 845             


Thr Asp Lys Arg Leu Leu Tyr Cys Ile Lys Ala Asp Pro His Cys Leu 
    850                 855                 860                 


Asn Phe Leu Cys Asn Phe Gly Lys Met Glu Ser Gly Lys Glu Ala Ser 
865                 870                 875                 880 


Val His Ile Gln Leu Glu Gly Arg Pro Ser Ile Leu Glu Met Asp Glu 
                885                 890                 895     


Thr Ser Ala Leu Lys Phe Glu Ile Arg Ala Thr Gly Phe Pro Glu Pro 
            900                 905                 910         


Asn Pro Arg Val Ile Glu Leu Asn Lys Asp Glu Asn Val Ala His Val 
        915                 920                 925             


Leu Leu Glu Gly Leu His His Gln Arg Pro Lys Arg Tyr Phe Thr 
    930                 935                 940             


<210>  728
<211>  954
<212>  PRT
<213>  Homo Sapiens

<400>  728

Phe Asn Leu Asp Ala Glu Ala Pro Ala Val Leu Ser Gly Pro Pro Gly 
1               5                   10                  15      


Ser Phe Phe Gly Phe Ser Val Glu Phe Tyr Arg Pro Gly Thr Asp Gly 
            20                  25                  30          


Val Ser Val Leu Val Gly Ala Pro Lys Ala Asn Thr Ser Gln Pro Gly 
        35                  40                  45              


Val Leu Gln Gly Gly Ala Val Tyr Leu Cys Pro Trp Gly Ala Ser Pro 
    50                  55                  60                  


Thr Gln Cys Thr Pro Ile Glu Phe Asp Ser Lys Gly Ser Arg Leu Leu 
65                  70                  75                  80  


Glu Ser Ser Leu Ser Ser Ser Glu Gly Glu Glu Pro Val Glu Tyr Lys 
                85                  90                  95      


Ser Leu Gln Trp Phe Gly Ala Thr Val Arg Ala His Gly Ser Ser Ile 
            100                 105                 110         


Leu Ala Cys Ala Pro Leu Tyr Ser Trp Arg Thr Glu Lys Glu Pro Leu 
        115                 120                 125             


Ser Asp Pro Val Gly Thr Cys Tyr Leu Ser Thr Asp Asn Phe Thr Arg 
    130                 135                 140                 


Ile Leu Glu Tyr Ala Pro Cys Arg Ser Asp Phe Ser Trp Ala Ala Gly 
145                 150                 155                 160 


Gln Gly Tyr Cys Gln Gly Gly Phe Ser Ala Glu Phe Thr Lys Thr Gly 
                165                 170                 175     


Arg Val Val Leu Gly Gly Pro Gly Ser Tyr Phe Trp Gln Gly Gln Ile 
            180                 185                 190         


Leu Ser Ala Thr Gln Glu Gln Ile Ala Glu Ser Tyr Tyr Pro Glu Tyr 
        195                 200                 205             


Leu Ile Asn Leu Val Gln Gly Gln Leu Gln Thr Arg Gln Ala Ser Ser 
    210                 215                 220                 


Ile Tyr Asp Asp Ser Tyr Leu Gly Tyr Ser Val Ala Val Gly Glu Phe 
225                 230                 235                 240 


Ser Gly Asp Asp Thr Glu Asp Phe Val Ala Gly Val Pro Lys Gly Asn 
                245                 250                 255     


Leu Thr Tyr Gly Tyr Val Thr Ile Leu Asn Gly Ser Asp Ile Arg Ser 
            260                 265                 270         


Leu Tyr Asn Phe Ser Gly Glu Gln Met Ala Ser Tyr Phe Gly Tyr Ala 
        275                 280                 285             


Val Ala Ala Thr Asp Val Asn Gly Asp Gly Leu Asp Asp Leu Leu Val 
    290                 295                 300                 


Gly Ala Pro Leu Leu Met Asp Arg Thr Pro Asp Gly Arg Pro Gln Glu 
305                 310                 315                 320 


Val Gly Arg Val Tyr Val Tyr Leu Gln His Pro Ala Gly Ile Glu Pro 
                325                 330                 335     


Thr Pro Thr Leu Thr Leu Thr Gly His Asp Glu Phe Gly Arg Phe Gly 
            340                 345                 350         


Ser Ser Leu Thr Pro Leu Gly Asp Leu Asp Gln Asp Gly Tyr Asn Asp 
        355                 360                 365             


Val Ala Ile Gly Ala Pro Phe Gly Gly Glu Thr Gln Gln Gly Val Val 
    370                 375                 380                 


Phe Val Phe Pro Gly Gly Pro Gly Gly Leu Gly Ser Lys Pro Ser Gln 
385                 390                 395                 400 


Val Leu Gln Pro Leu Trp Ala Ala Ser His Thr Pro Asp Phe Phe Gly 
                405                 410                 415     


Ser Ala Leu Arg Gly Gly Arg Asp Leu Asp Gly Asn Gly Tyr Pro Asp 
            420                 425                 430         


Leu Ile Val Gly Ser Phe Gly Val Asp Lys Ala Val Val Tyr Arg Gly 
        435                 440                 445             


Arg Pro Ile Val Ser Ala Ser Ala Ser Leu Thr Ile Phe Pro Ala Met 
    450                 455                 460                 


Phe Asn Pro Glu Glu Arg Ser Cys Ser Leu Glu Gly Asn Pro Val Ala 
465                 470                 475                 480 


Cys Ile Asn Leu Ser Phe Cys Leu Asn Ala Ser Gly Lys His Val Ala 
                485                 490                 495     


Asp Ser Ile Gly Phe Thr Val Glu Leu Gln Leu Asp Trp Gln Lys Gln 
            500                 505                 510         


Lys Gly Gly Val Arg Arg Ala Leu Phe Leu Ala Ser Arg Gln Ala Thr 
        515                 520                 525             


Leu Thr Gln Thr Leu Leu Ile Gln Asn Gly Ala Arg Glu Asp Cys Arg 
    530                 535                 540                 


Glu Met Lys Ile Tyr Leu Arg Asn Glu Ser Glu Phe Arg Asp Lys Leu 
545                 550                 555                 560 


Ser Pro Ile His Ile Ala Leu Asn Phe Ser Leu Asp Pro Gln Ala Pro 
                565                 570                 575     


Val Asp Ser His Gly Leu Arg Pro Ala Leu His Tyr Gln Ser Lys Ser 
            580                 585                 590         


Arg Ile Glu Asp Lys Ala Gln Ile Leu Leu Asp Cys Gly Glu Asp Asn 
        595                 600                 605             


Ile Cys Val Pro Asp Leu Gln Leu Glu Val Phe Gly Glu Gln Asn His 
    610                 615                 620                 


Val Tyr Leu Gly Asp Lys Asn Ala Leu Asn Leu Thr Phe His Ala Gln 
625                 630                 635                 640 


Asn Val Gly Glu Gly Gly Ala Tyr Glu Ala Glu Leu Arg Val Thr Ala 
                645                 650                 655     


Pro Pro Glu Ala Glu Tyr Ser Gly Leu Val Arg His Pro Gly Asn Phe 
            660                 665                 670         


Ser Ser Leu Ser Cys Asp Tyr Phe Ala Val Asn Gln Ser Arg Leu Leu 
        675                 680                 685             


Val Cys Asp Leu Gly Asn Pro Met Lys Ala Gly Ala Ser Leu Trp Gly 
    690                 695                 700                 


Gly Leu Arg Phe Thr Val Pro His Leu Arg Asp Thr Lys Lys Thr Ile 
705                 710                 715                 720 


Gln Phe Asp Phe Gln Ile Leu Ser Lys Asn Leu Asn Asn Ser Gln Ser 
                725                 730                 735     


Asp Val Val Ser Phe Arg Leu Ser Val Glu Ala Gln Ala Gln Val Thr 
            740                 745                 750         


Leu Asn Gly Val Ser Lys Pro Glu Ala Val Leu Phe Pro Val Ser Asp 
        755                 760                 765             


Trp His Pro Arg Asp Gln Pro Gln Lys Glu Glu Asp Leu Gly Pro Ala 
    770                 775                 780                 


Val His His Val Tyr Glu Leu Ile Asn Gln Gly Pro Ser Ser Ile Ser 
785                 790                 795                 800 


Gln Gly Val Leu Glu Leu Ser Cys Pro Gln Ala Leu Glu Gly Gln Gln 
                805                 810                 815     


Leu Leu Tyr Val Thr Arg Val Thr Gly Leu Asn Cys Thr Thr Asn His 
            820                 825                 830         


Pro Ile Asn Pro Lys Gly Leu Glu Leu Asp Pro Glu Gly Ser Leu His 
        835                 840                 845             


His Gln Gln Lys Arg Glu Ala Pro Ser Arg Ser Ser Ala Ser Ser Gly 
    850                 855                 860                 


Pro Gln Ile Leu Lys Cys Pro Glu Ala Glu Cys Phe Arg Leu Arg Cys 
865                 870                 875                 880 


Glu Leu Gly Pro Leu His Gln Gln Glu Ser Gln Ser Leu Gln Leu His 
                885                 890                 895     


Phe Arg Val Trp Ala Lys Thr Phe Leu Gln Arg Glu His Gln Pro Phe 
            900                 905                 910         


Ser Leu Gln Cys Glu Ala Val Tyr Lys Ala Leu Lys Met Pro Tyr Arg 
        915                 920                 925             


Ile Leu Pro Arg Gln Leu Pro Gln Lys Glu Arg Gln Val Ala Thr Ala 
    930                 935                 940                 


Val Gln Trp Thr Lys Ala Glu Gly Ser Tyr 
945                 950                 


<210>  729
<211>  988
<212>  PRT
<213>  Homo Sapiens

<400>  729

Phe Asn Leu Asp Thr Arg Glu Asp Asn Val Ile Arg Lys Tyr Gly Asp 
1               5                   10                  15      


Pro Gly Ser Leu Phe Gly Phe Ser Leu Ala Met His Trp Gln Leu Gln 
            20                  25                  30          


Pro Glu Asp Lys Arg Leu Leu Leu Val Gly Ala Pro Arg Ala Glu Ala 
        35                  40                  45              


Leu Pro Leu Gln Arg Ala Asn Arg Thr Gly Gly Leu Tyr Ser Cys Asp 
    50                  55                  60                  


Ile Thr Ala Arg Gly Pro Cys Thr Arg Ile Glu Phe Asp Asn Asp Ala 
65                  70                  75                  80  


Asp Pro Thr Ser Glu Ser Lys Glu Asp Gln Trp Met Gly Val Thr Val 
                85                  90                  95      


Gln Ser Gln Gly Pro Gly Gly Lys Val Val Thr Cys Ala His Arg Tyr 
            100                 105                 110         


Glu Lys Arg Gln His Val Asn Thr Lys Gln Glu Ser Arg Asp Ile Phe 
        115                 120                 125             


Gly Arg Cys Tyr Val Leu Ser Gln Asn Leu Arg Ile Glu Asp Asp Met 
    130                 135                 140                 


Asp Gly Gly Asp Trp Ser Phe Cys Asp Gly Arg Leu Arg Gly His Glu 
145                 150                 155                 160 


Lys Phe Gly Ser Cys Gln Gln Gly Val Ala Ala Thr Phe Thr Lys Asp 
                165                 170                 175     


Phe His Tyr Ile Val Phe Gly Ala Pro Gly Thr Tyr Asn Trp Lys Gly 
            180                 185                 190         


Ile Val Arg Val Glu Gln Lys Asn Asn Thr Phe Phe Asp Met Asn Ile 
        195                 200                 205             


Phe Glu Asp Gly Pro Tyr Glu Val Gly Gly Glu Thr Glu His Asp Glu 
    210                 215                 220                 


Ser Leu Val Pro Val Pro Ala Asn Ser Tyr Leu Gly Phe Ser Leu Asp 
225                 230                 235                 240 


Ser Gly Lys Gly Ile Val Ser Lys Asp Glu Ile Thr Phe Val Ser Gly 
                245                 250                 255     


Ala Pro Arg Ala Asn His Ser Gly Ala Val Val Leu Leu Lys Arg Asp 
            260                 265                 270         


Met Lys Ser Ala His Leu Leu Pro Glu His Ile Phe Asp Gly Glu Gly 
        275                 280                 285             


Leu Ala Ser Ser Phe Gly Tyr Asp Val Ala Val Val Asp Leu Asn Lys 
    290                 295                 300                 


Asp Gly Trp Gln Asp Ile Val Ile Gly Ala Pro Gln Tyr Phe Asp Arg 
305                 310                 315                 320 


Asp Gly Glu Val Gly Gly Ala Val Tyr Val Tyr Met Asn Gln Gln Gly 
                325                 330                 335     


Arg Trp Asn Asn Val Lys Pro Ile Arg Leu Asn Gly Thr Lys Asp Ser 
            340                 345                 350         


Met Phe Gly Ile Thr Val Lys Asn Ile Gly Asp Ile Asn Gln Asp Gly 
        355                 360                 365             


Tyr Pro Asp Ile Ala Val Gly Ala Pro Tyr Asp Asp Leu Gly Lys Val 
    370                 375                 380                 


Phe Ile Tyr His Gly Ser Ala Asn Gly Ile Asn Thr Lys Pro Thr Gln 
385                 390                 395                 400 


Val Leu Lys Gly Ile Ser Pro Tyr Phe Gly Tyr Ser Ile Ala Gly Asn 
                405                 410                 415     


Met Asp Leu Asp Arg Asn Ser Tyr Pro Asp Val Ala Val Gly Ser Leu 
            420                 425                 430         


Ser Asp Ser Val Thr Ile Phe Arg Ser Arg Pro Val Ile Asn Ile Gln 
        435                 440                 445             


Lys Thr Ile Thr Val Thr Pro Asn Arg Ile Asp Leu Arg Gln Lys Thr 
    450                 455                 460                 


Ala Cys Gly Ala Pro Ser Gly Ile Cys Leu Gln Val Lys Ser Cys Phe 
465                 470                 475                 480 


Glu Tyr Thr Ala Asn Pro Ala Gly Tyr Asn Pro Ser Ile Ser Ile Val 
                485                 490                 495     


Gly Thr Leu Glu Ala Glu Lys Glu Arg Arg Lys Ser Gly Leu Ser Ser 
            500                 505                 510         


Arg Val Gln Phe Arg Asn Gln Gly Ser Glu Pro Lys Tyr Thr Gln Glu 
        515                 520                 525             


Leu Thr Leu Lys Arg Gln Lys Gln Lys Val Cys Met Glu Glu Thr Leu 
    530                 535                 540                 


Trp Leu Gln Asp Asn Ile Arg Asp Lys Leu Arg Pro Ile Pro Ile Thr 
545                 550                 555                 560 


Ala Ser Val Glu Ile Gln Glu Pro Ser Ser Arg Arg Arg Val Asn Ser 
                565                 570                 575     


Leu Pro Glu Val Leu Pro Ile Leu Asn Ser Asp Glu Pro Lys Thr Ala 
            580                 585                 590         


His Ile Asp Val His Phe Leu Lys Glu Gly Cys Gly Asp Asp Asn Val 
        595                 600                 605             


Cys Asn Ser Asn Leu Lys Leu Glu Tyr Lys Phe Cys Thr Arg Glu Gly 
    610                 615                 620                 


Asn Gln Asp Lys Phe Ser Tyr Leu Pro Ile Gln Lys Gly Val Pro Glu 
625                 630                 635                 640 


Leu Val Leu Lys Asp Gln Lys Asp Ile Ala Leu Glu Ile Thr Val Thr 
                645                 650                 655     


Asn Ser Pro Ser Asn Pro Arg Asn Pro Thr Lys Asp Gly Asp Asp Ala 
            660                 665                 670         


His Glu Ala Lys Leu Ile Ala Thr Phe Pro Asp Thr Leu Thr Tyr Ser 
        675                 680                 685             


Ala Tyr Arg Glu Leu Arg Ala Phe Pro Glu Lys Gln Leu Ser Cys Val 
    690                 695                 700                 


Ala Asn Gln Asn Gly Ser Gln Ala Asp Cys Glu Leu Gly Asn Pro Phe 
705                 710                 715                 720 


Lys Arg Asn Ser Asn Val Thr Phe Tyr Leu Val Leu Ser Thr Thr Glu 
                725                 730                 735     


Val Thr Phe Asp Thr Pro Asp Leu Asp Ile Asn Leu Lys Leu Glu Thr 
            740                 745                 750         


Thr Ser Asn Gln Asp Asn Leu Ala Pro Ile Thr Ala Lys Ala Lys Val 
        755                 760                 765             


Val Ile Glu Leu Leu Leu Ser Val Ser Gly Val Ala Lys Pro Ser Gln 
    770                 775                 780                 


Val Tyr Phe Gly Gly Thr Val Val Gly Glu Gln Ala Met Lys Ser Glu 
785                 790                 795                 800 


Asp Glu Val Gly Ser Leu Ile Glu Tyr Glu Phe Arg Val Ile Asn Leu 
                805                 810                 815     


Gly Lys Pro Leu Thr Asn Leu Gly Thr Ala Thr Leu Asn Ile Gln Trp 
            820                 825                 830         


Pro Lys Glu Ile Ser Asn Gly Lys Trp Leu Leu Tyr Leu Val Lys Val 
        835                 840                 845             


Glu Ser Lys Gly Leu Glu Lys Val Thr Cys Glu Pro Gln Lys Glu Ile 
    850                 855                 860                 


Asn Ser Leu Asn Leu Thr Glu Ser His Asn Ser Arg Lys Lys Arg Glu 
865                 870                 875                 880 


Ile Thr Glu Lys Gln Ile Asp Asp Asn Arg Lys Phe Ser Leu Phe Ala 
                885                 890                 895     


Glu Arg Lys Tyr Gln Thr Leu Asn Cys Ser Val Asn Val Asn Cys Val 
            900                 905                 910         


Asn Ile Arg Cys Pro Leu Arg Gly Leu Asp Ser Lys Ala Ser Leu Ile 
        915                 920                 925             


Leu Arg Ser Arg Leu Trp Asn Ser Thr Phe Leu Glu Glu Tyr Ser Lys 
    930                 935                 940                 


Leu Asn Tyr Leu Asp Ile Leu Met Arg Ala Phe Ile Asp Val Thr Ala 
945                 950                 955                 960 


Ala Ala Glu Asn Ile Arg Leu Pro Asn Ala Gly Thr Gln Val Arg Val 
                965                 970                 975     


Thr Val Phe Pro Ser Lys Thr Val Ala Gln Tyr Ser 
            980                 985             


<210>  730
<211>  1005
<212>  PRT
<213>  Homo Sapiens

<400>  730

Phe Asn Leu Asp Val Met Gly Ala Leu Arg Lys Glu Gly Glu Pro Gly 
1               5                   10                  15      


Ser Leu Phe Gly Phe Ser Val Ala Leu His Arg Gln Leu Gln Pro Arg 
            20                  25                  30          


Pro Gln Ser Trp Leu Leu Val Gly Ala Pro Gln Ala Leu Ala Leu Pro 
        35                  40                  45              


Gly Gln Gln Ala Asn Arg Thr Gly Gly Leu Phe Ala Cys Pro Leu Ser 
    50                  55                  60                  


Leu Glu Glu Thr Asp Cys Tyr Arg Val Asp Ile Asp Gln Gly Ala Asp 
65                  70                  75                  80  


Met Gln Lys Glu Ser Lys Glu Asn Gln Trp Leu Gly Val Ser Val Arg 
                85                  90                  95      


Ser Gln Gly Pro Gly Gly Lys Ile Val Thr Cys Ala His Arg Tyr Glu 
            100                 105                 110         


Ala Arg Gln Arg Val Asp Gln Ile Leu Glu Thr Arg Asp Met Ile Gly 
        115                 120                 125             


Arg Cys Phe Val Leu Ser Gln Asp Leu Ala Ile Arg Asp Glu Leu Asp 
    130                 135                 140                 


Gly Gly Glu Trp Lys Phe Cys Glu Gly Arg Pro Gln Gly His Glu Gln 
145                 150                 155                 160 


Phe Gly Phe Cys Gln Gln Gly Thr Ala Ala Ala Phe Ser Pro Asp Ser 
                165                 170                 175     


His Tyr Leu Leu Phe Gly Ala Pro Gly Thr Tyr Asn Trp Lys Gly Leu 
            180                 185                 190         


Leu Phe Val Thr Asn Ile Asp Ser Ser Asp Pro Asp Gln Leu Val Tyr 
        195                 200                 205             


Lys Thr Leu Asp Pro Ala Asp Arg Leu Pro Gly Pro Ala Gly Asp Leu 
    210                 215                 220                 


Ala Leu Asn Ser Tyr Leu Gly Phe Ser Ile Asp Ser Gly Lys Gly Leu 
225                 230                 235                 240 


Val Arg Ala Glu Glu Leu Ser Phe Val Ala Gly Ala Pro Arg Ala Asn 
                245                 250                 255     


His Lys Gly Ala Val Val Ile Leu Arg Lys Asp Ser Ala Ser Arg Leu 
            260                 265                 270         


Val Pro Glu Val Met Leu Ser Gly Glu Arg Leu Thr Ser Gly Phe Gly 
        275                 280                 285             


Tyr Ser Leu Ala Val Ala Asp Leu Asn Ser Asp Gly Trp Pro Asp Leu 
    290                 295                 300                 


Ile Val Gly Ala Pro Tyr Phe Phe Glu Arg Gln Glu Glu Leu Gly Gly 
305                 310                 315                 320 


Ala Val Tyr Val Tyr Leu Asn Gln Gly Gly His Trp Ala Gly Ile Ser 
                325                 330                 335     


Pro Leu Arg Leu Cys Gly Ser Pro Asp Ser Met Phe Gly Ile Ser Leu 
            340                 345                 350         


Ala Val Leu Gly Asp Leu Asn Gln Asp Gly Phe Pro Asp Ile Ala Val 
        355                 360                 365             


Gly Ala Pro Phe Asp Gly Asp Gly Lys Val Phe Val Tyr His Gly Ser 
    370                 375                 380                 


Ser Leu Gly Val Val Ala Lys Pro Ser Gln Val Leu Glu Gly Glu Ala 
385                 390                 395                 400 


Val Gly Ile Lys Ser Phe Gly Tyr Ser Leu Ser Gly Ser Leu Asp Met 
                405                 410                 415     


Asp Gly Asn Gln Tyr Pro Asp Leu Leu Val Gly Ser Met Ala Asp Thr 
            420                 425                 430         


Ala Val Leu Phe Arg Ala Arg Pro Ile Leu His Val Ser His Glu Val 
        435                 440                 445             


Ser Ile Ala Pro Arg Ser Ile Asp Leu Glu Gln Pro Asn Cys Ala Gly 
    450                 455                 460                 


Gly His Ser Val Cys Val Asp Leu Arg Val Cys Phe Ser Tyr Ile Ala 
465                 470                 475                 480 


Val Pro Ser Ser Tyr Ser Pro Thr Val Ala Leu Asp Tyr Val Leu Asp 
                485                 490                 495     


Ala Asp Thr Asp Arg Arg Leu Arg Gly Gln Val Pro His Val Thr Phe 
            500                 505                 510         


Leu Ser Arg Asn Leu Glu Glu Pro Lys His Gln Ala Ser Gly Thr Val 
        515                 520                 525             


Trp Leu Lys His Gln His Asp Arg Val Cys Gly Asp Ala Met Phe Gln 
    530                 535                 540                 


Leu Gln Glu Asn Val Lys Asp Lys Leu Arg Ala Ile Val Val Thr Leu 
545                 550                 555                 560 


Ser Tyr Ser Leu Gln Thr Pro Arg Leu Arg Arg Gln Ala Pro Gly Gln 
                565                 570                 575     


Gly Leu Pro Pro Val Ala Pro Ile Leu Asn Ala His Gln Pro Ser Thr 
            580                 585                 590         


Gln Arg Ala Glu Ile His Phe Leu Lys Gln Gly Cys Gly Glu Asp Lys 
        595                 600                 605             


Ile Cys Gln Ser Asn Leu Gln Leu Val His Val Arg Phe Cys Thr Arg 
    610                 615                 620                 


Val Ser Asp Thr Glu Phe Gln Pro Leu Pro Met Asp Val Asp Gly Thr 
625                 630                 635                 640 


Thr Ala Leu Phe Ala Leu Ser Gly Gln Pro Val Ile Gly Leu Glu Leu 
                645                 650                 655     


Met Val Thr Asn Leu Pro Ser Asp Pro Ala Gln Pro Gln Ala Asp Gly 
            660                 665                 670         


Asp Asp Ala His Glu Ala Gln Leu Leu Val Met Leu Pro Asp Ser Leu 
        675                 680                 685             


His Tyr Ser Gly Val Arg Ala Leu Asp Pro Ala Glu Lys Pro Leu Cys 
    690                 695                 700                 


Leu Ser Asn Glu Asn Ala Ser His Val Glu Cys Glu Leu Gly Asn Pro 
705                 710                 715                 720 


Met Lys Arg Gly Ala Gln Val Thr Phe Tyr Leu Ile Leu Ser Thr Ser 
                725                 730                 735     


Gly Ile Ser Ile Glu Thr Thr Glu Leu Glu Val Glu Leu Leu Leu Ala 
            740                 745                 750         


Thr Ile Ser Glu Gln Glu Leu His Pro Val Ser Ala Arg Ala Arg Val 
        755                 760                 765             


Phe Ile Glu Leu Pro Leu Ser Ile Ala Gly Met Ala Ile Pro Gln Gln 
    770                 775                 780                 


Leu Phe Phe Ser Gly Val Val Arg Gly Glu Arg Ala Met Gln Ser Glu 
785                 790                 795                 800 


Arg Asp Val Gly Ser Lys Val Lys Tyr Glu Val Thr Val Ser Asn Gln 
                805                 810                 815     


Gly Gln Ser Leu Arg Thr Leu Gly Ser Ala Phe Leu Asn Ile Met Trp 
            820                 825                 830         


Pro His Glu Ile Ala Asn Gly Lys Trp Leu Leu Tyr Pro Met Gln Val 
        835                 840                 845             


Glu Leu Glu Gly Gly Gln Gly Pro Gly Gln Lys Gly Leu Cys Ser Pro 
    850                 855                 860                 


Arg Pro Asn Ile Leu His Leu Asp Val Asp Ser Arg Asp Arg Arg Arg 
865                 870                 875                 880 


Arg Glu Leu Glu Pro Pro Glu Gln Gln Glu Pro Gly Glu Arg Gln Glu 
                885                 890                 895     


Pro Ser Met Ser Trp Trp Pro Val Ser Ser Ala Glu Lys Lys Lys Asn 
            900                 905                 910         


Ile Thr Leu Asp Cys Ala Arg Gly Thr Ala Asn Cys Val Val Phe Ser 
        915                 920                 925             


Cys Pro Leu Tyr Ser Phe Asp His Ala Ala Val Leu His Val Trp Gly 
    930                 935                 940                 


Arg Leu Trp Asn Ser Thr Phe Leu Glu Glu Tyr Ser Ala Val Lys Ser 
945                 950                 955                 960 


Leu Glu Val Ile Val Arg Ala Asn Ile Thr Val Lys Ser Ser Ile Lys 
                965                 970                 975     


Asn Leu Met Leu Arg Asp Ala Ser Thr Val Ile Pro Val Met Val Tyr 
            980                 985                 990         


Leu Asp Pro Met Ala Val Val Ala  Glu Gly Val Pro Trp  
        995                 1000                 1005 


<210>  731
<211>  974
<212>  PRT
<213>  Homo Sapiens

<400>  731

Phe Asn Leu Asp Val Glu Lys Leu Thr Val Tyr Ser Gly Pro Lys Gly 
1               5                   10                  15      


Ser Tyr Phe Gly Tyr Ala Val Asp Phe His Ile Pro Asp Ala Arg Thr 
            20                  25                  30          


Ala Ser Val Leu Val Gly Ala Pro Lys Ala Asn Thr Ser Gln Pro Asp 
        35                  40                  45              


Ile Val Glu Gly Gly Ala Val Tyr Tyr Cys Pro Trp Pro Ala Glu Gly 
    50                  55                  60                  


Ser Ala Gln Cys Arg Gln Ile Pro Phe Asp Thr Thr Asn Asn Arg Lys 
65                  70                  75                  80  


Ile Arg Val Asn Gly Thr Lys Glu Pro Ile Glu Phe Lys Ser Asn Gln 
                85                  90                  95      


Trp Phe Gly Ala Thr Val Lys Ala His Lys Gly Lys Val Val Ala Cys 
            100                 105                 110         


Ala Pro Leu Tyr His Trp Arg Thr Leu Lys Pro Thr Pro Glu Lys Asp 
        115                 120                 125             


Pro Val Gly Thr Cys Tyr Val Ala Ile Gln Asn Phe Ser Ala Tyr Ala 
    130                 135                 140                 


Glu Phe Ser Pro Cys Arg Asn Ser Asn Ala Asp Pro Glu Gly Gln Gly 
145                 150                 155                 160 


Tyr Cys Gln Ala Gly Phe Ser Leu Asp Phe Tyr Lys Asn Gly Asp Leu 
                165                 170                 175     


Ile Val Gly Gly Pro Gly Ser Phe Tyr Trp Gln Gly Gln Val Ile Thr 
            180                 185                 190         


Ala Ser Val Ala Asp Ile Ile Ala Asn Tyr Ser Phe Lys Asp Ile Leu 
        195                 200                 205             


Arg Lys Leu Ala Gly Glu Lys Gln Thr Glu Val Ala Pro Ala Ser Tyr 
    210                 215                 220                 


Asp Asp Ser Tyr Leu Gly Tyr Ser Val Ala Ala Gly Glu Phe Thr Gly 
225                 230                 235                 240 


Asp Ser Gln Gln Glu Leu Val Ala Gly Ile Pro Arg Gly Ala Gln Asn 
                245                 250                 255     


Phe Gly Tyr Val Ser Ile Ile Asn Ser Thr Asp Met Thr Phe Ile Gln 
            260                 265                 270         


Asn Phe Thr Gly Glu Gln Met Ala Ser Tyr Phe Gly Tyr Thr Val Val 
        275                 280                 285             


Val Ser Asp Val Asn Ser Asp Gly Leu Asp Asp Val Leu Val Gly Ala 
    290                 295                 300                 


Pro Leu Phe Met Glu Arg Glu Phe Glu Ser Asn Pro Arg Glu Val Gly 
305                 310                 315                 320 


Gln Ile Tyr Leu Tyr Leu Gln Val Ser Ser Leu Leu Phe Arg Asp Pro 
                325                 330                 335     


Gln Ile Leu Thr Gly Thr Glu Thr Phe Gly Arg Phe Gly Ser Ala Met 
            340                 345                 350         


Ala His Leu Gly Asp Leu Asn Gln Asp Gly Tyr Asn Asp Ile Ala Ile 
        355                 360                 365             


Gly Val Pro Phe Ala Gly Lys Asp Gln Arg Gly Lys Val Leu Ile Tyr 
    370                 375                 380                 


Asn Gly Asn Lys Asp Gly Leu Asn Thr Lys Pro Ser Gln Val Leu Gln 
385                 390                 395                 400 


Gly Val Trp Ala Ser His Ala Val Pro Ser Gly Phe Gly Phe Thr Leu 
                405                 410                 415     


Arg Gly Asp Ser Asp Ile Asp Lys Asn Asp Tyr Pro Asp Leu Ile Val 
            420                 425                 430         


Gly Ala Phe Gly Thr Gly Lys Val Ala Val Tyr Arg Ala Arg Pro Val 
        435                 440                 445             


Val Thr Val Asp Ala Gln Leu Leu Leu His Pro Met Ile Ile Asn Leu 
    450                 455                 460                 


Glu Asn Lys Thr Cys Gln Val Pro Asp Ser Met Thr Ser Ala Ala Cys 
465                 470                 475                 480 


Phe Ser Leu Arg Val Cys Ala Ser Val Thr Gly Gln Ser Ile Ala Asn 
                485                 490                 495     


Thr Ile Val Leu Met Ala Glu Val Gln Leu Asp Ser Leu Lys Gln Lys 
            500                 505                 510         


Gly Ala Ile Lys Arg Thr Leu Phe Leu Asp Asn His Gln Ala His Arg 
        515                 520                 525             


Val Phe Pro Leu Val Ile Lys Arg Gln Lys Ser His Gln Cys Gln Asp 
    530                 535                 540                 


Phe Ile Val Tyr Leu Arg Asp Glu Thr Glu Phe Arg Asp Lys Leu Ser 
545                 550                 555                 560 


Pro Ile Asn Ile Ser Leu Asn Tyr Ser Leu Asp Glu Ser Thr Phe Lys 
                565                 570                 575     


Glu Gly Leu Glu Val Lys Pro Ile Leu Asn Tyr Tyr Arg Glu Asn Ile 
            580                 585                 590         


Val Ser Glu Gln Ala His Ile Leu Val Asp Cys Gly Glu Asp Asn Leu 
        595                 600                 605             


Cys Val Pro Asp Leu Lys Leu Ser Ala Arg Pro Asp Lys His Gln Val 
    610                 615                 620                 


Ile Ile Gly Asp Glu Asn His Leu Met Leu Ile Ile Asn Ala Arg Asn 
625                 630                 635                 640 


Glu Gly Glu Gly Ala Tyr Glu Ala Glu Leu Phe Val Met Ile Pro Glu 
                645                 650                 655     


Glu Ala Asp Tyr Val Gly Ile Glu Arg Asn Asn Lys Gly Phe Arg Pro 
            660                 665                 670         


Leu Ser Cys Glu Tyr Lys Met Glu Asn Val Thr Arg Met Val Val Cys 
        675                 680                 685             


Asp Leu Gly Asn Pro Met Val Ser Gly Thr Asn Tyr Ser Leu Gly Leu 
    690                 695                 700                 


Arg Phe Ala Val Pro Arg Leu Glu Lys Thr Asn Met Ser Ile Asn Phe 
705                 710                 715                 720 


Asp Leu Gln Ile Arg Ser Ser Asn Lys Asp Asn Pro Asp Ser Asn Phe 
                725                 730                 735     


Val Ser Leu Gln Ile Asn Ile Thr Ala Val Ala Gln Val Glu Ile Arg 
            740                 745                 750         


Gly Val Ser His Pro Pro Gln Ile Val Leu Pro Ile His Asn Trp Glu 
        755                 760                 765             


Pro Glu Glu Glu Pro His Lys Glu Glu Glu Val Gly Pro Leu Val Glu 
    770                 775                 780                 


His Ile Tyr Glu Leu His Asn Ile Gly Pro Ser Thr Ile Ser Asp Thr 
785                 790                 795                 800 


Ile Leu Glu Val Gly Trp Pro Phe Ser Ala Arg Asp Glu Phe Leu Leu 
                805                 810                 815     


Tyr Ile Phe His Ile Gln Thr Leu Gly Pro Leu Gln Cys Gln Pro Asn 
            820                 825                 830         


Pro Asn Ile Asn Pro Gln Asp Ile Lys Pro Ala Ala Ser Pro Glu Asp 
        835                 840                 845             


Thr Pro Glu Leu Ser Ala Phe Leu Arg Asn Ser Thr Ile Pro His Leu 
    850                 855                 860                 


Val Arg Lys Arg Asp Val His Val Val Glu Phe His Arg Gln Ser Pro 
865                 870                 875                 880 


Ala Lys Ile Leu Asn Cys Thr Asn Ile Glu Cys Leu Gln Ile Ser Cys 
                885                 890                 895     


Ala Val Gly Arg Leu Glu Gly Gly Glu Ser Ala Val Leu Lys Val Arg 
            900                 905                 910         


Ser Arg Leu Trp Ala His Thr Phe Leu Gln Arg Lys Asn Asp Pro Tyr 
        915                 920                 925             


Ala Leu Ala Ser Leu Val Ser Phe Glu Val Lys Lys Met Pro Tyr Thr 
    930                 935                 940                 


Asp Gln Pro Ala Lys Leu Pro Glu Gly Ser Ile Ala Ile Lys Thr Ser 
945                 950                 955                 960 


Val Ile Trp Ala Thr Pro Asn Val Ser Phe Ser Ile Pro Leu 
                965                 970                 


<210>  732
<211>  536
<212>  PRT
<213>  Homo Sapiens

<400>  732

Tyr Asn Leu Asp Pro Gln Arg Pro Val His Phe Gln Gly Pro Ala Asp 
1               5                   10                  15      


Ser Phe Phe Gly Tyr Ala Val Leu Glu His Phe His Asp Asn Thr Arg 
            20                  25                  30          


Trp Val Leu Val Gly Ala Pro Lys Ala Asp Ser Lys Tyr Ser Pro Ser 
        35                  40                  45              


Val Lys Ser Pro Gly Ala Val Phe Lys Cys Arg Val His Thr Asn Pro 
    50                  55                  60                  


Asp Arg Arg Cys Thr Glu Leu Asp Met Ala Arg Gly Lys Asn Arg Gly 
65                  70                  75                  80  


Thr Ser Cys Gly Lys Thr Cys Arg Glu Asp Arg Asp Asp Glu Trp Met 
                85                  90                  95      


Gly Val Ser Leu Ala Arg Gln Pro Lys Ala Asp Gly Arg Val Leu Ala 
            100                 105                 110         


Cys Ala His Arg Trp Lys Asn Ile Tyr Tyr Glu Ala Asp His Ile Leu 
        115                 120                 125             


Pro His Gly Phe Cys Tyr Ile Ile Pro Ser Asn Leu Gln Ala Lys Gly 
    130                 135                 140                 


Arg Thr Leu Ile Pro Cys Tyr Glu Glu Tyr Lys Lys Lys Tyr Gly Glu 
145                 150                 155                 160 


Glu His Gly Ser Cys Gln Ala Gly Ile Ala Gly Phe Phe Thr Glu Glu 
                165                 170                 175     


Leu Val Val Met Gly Ala Pro Gly Ser Phe Tyr Trp Ala Gly Thr Ile 
            180                 185                 190         


Lys Val Leu Asn Leu Thr Asp Asn Thr Tyr Leu Lys Leu Asn Asp Glu 
        195                 200                 205             


Val Ile Met Asn Arg Arg Tyr Thr Tyr Leu Gly Tyr Ala Val Thr Ala 
    210                 215                 220                 


Gly His Phe Ser His Pro Ser Thr Ile Asp Val Val Gly Gly Ala Pro 
225                 230                 235                 240 


Gln Asp Lys Gly Ile Gly Lys Val Tyr Ile Phe Arg Ala Asp Arg Arg 
                245                 250                 255     


Ser Gly Thr Leu Ile Lys Ile Phe Gln Ala Ser Gly Lys Lys Met Gly 
            260                 265                 270         


Ser Tyr Phe Gly Ser Ser Leu Cys Ala Val Asp Leu Asn Gly Asp Gly 
        275                 280                 285             


Leu Ser Asp Leu Leu Val Gly Ala Pro Met Phe Ser Glu Ile Arg Asp 
    290                 295                 300                 


Glu Gly Gln Val Thr Val Tyr Ile Asn Arg Gly Asn Gly Ala Leu Glu 
305                 310                 315                 320 


Glu Gln Leu Ala Leu Thr Gly Asp Gly Ala Tyr Asn Ala His Phe Gly 
                325                 330                 335     


Glu Ser Ile Ala Ser Leu Asp Asp Leu Asp Asn Asp Gly Phe Pro Asp 
            340                 345                 350         


Val Ala Ile Gly Ala Pro Lys Glu Asp Asp Phe Ala Gly Ala Val Tyr 
        355                 360                 365             


Ile Tyr His Gly Asp Ala Gly Gly Ile Val Pro Gln Tyr Ser Met Lys 
    370                 375                 380                 


Leu Ser Gly Gln Lys Ile Asn Pro Val Leu Arg Met Phe Gly Gln Ser 
385                 390                 395                 400 


Ile Ser Gly Gly Ile Asp Met Asp Gly Asn Gly Tyr Pro Asp Val Thr 
                405                 410                 415     


Val Gly Ala Phe Met Ser Asp Ser Val Val Leu Leu Arg Ala Arg Pro 
            420                 425                 430         


Val Ile Thr Val Asp Val Ser Ile Phe Leu Pro Gly Ser Ile Asn Ile 
        435                 440                 445             


Thr Ala Pro Gln Cys His Asp Gly Gln Gln Pro Val Asn Cys Leu Asn 
    450                 455                 460                 


Val Thr Thr Cys Phe Ser Phe His Gly Lys His Val Pro Glu Glu Ile 
465                 470                 475                 480 


Gly Leu Asn Tyr Val Leu Met Ala Asp Val Ala Lys Lys Glu Lys Gly 
                485                 490                 495     


Gln Met Pro Arg Val Tyr Phe Val Leu Leu Gly Glu Thr Met Gly Gln 
            500                 505                 510         


Val Thr Glu Lys Leu Gln Leu Thr Tyr Met Glu Glu Thr Cys Arg His 
        515                 520                 525             


Tyr Val Ala His Val Lys Arg Arg 
    530                 535     


<210>  733
<211>  1106
<212>  PRT
<213>  Homo Sapiens

<400>  733

Phe Asn Val Asp Val Ala Arg Pro Trp Leu Thr Pro Lys Gly Gly Ala 
1               5                   10                  15      


Pro Phe Val Leu Ser Ser Leu Leu His Gln Asp Pro Ser Thr Asn Gln 
            20                  25                  30          


Thr Trp Leu Leu Val Thr Ser Pro Arg Thr Lys Arg Thr Pro Gly Pro 
        35                  40                  45              


Leu His Arg Cys Ser Leu Val Gln Asp Glu Ile Leu Cys His Pro Val 
    50                  55                  60                  


Glu His Val Pro Ile Pro Lys Gly Arg His Arg Gly Val Thr Val Val 
65                  70                  75                  80  


Arg Ser His His Gly Val Leu Ile Cys Ile Gln Val Leu Val Arg Arg 
                85                  90                  95      


Pro His Ser Leu Ser Ser Glu Leu Thr Gly Thr Cys Ser Leu Leu Gly 
            100                 105                 110         


Pro Asp Leu Arg Pro Gln Ala Gln Ala Asn Phe Phe Asp Leu Glu Asn 
        115                 120                 125             


Leu Leu Asp Pro Asp Ala Arg Val Asp Thr Gly Asp Cys Tyr Ser Asn 
    130                 135                 140                 


Lys Glu Gly Gly Gly Glu Asp Asp Val Asn Thr Ala Arg Gln Arg Arg 
145                 150                 155                 160 


Ala Leu Glu Lys Glu Glu Glu Glu Asp Lys Glu Glu Glu Glu Asp Glu 
                165                 170                 175     


Glu Glu Glu Glu Ala Gly Thr Glu Ile Ala Ile Ile Leu Asp Gly Ser 
            180                 185                 190         


Gly Ser Ile Asp Pro Pro Asp Phe Gln Arg Ala Lys Asp Phe Ile Ser 
        195                 200                 205             


Asn Met Met Arg Asn Phe Tyr Glu Lys Cys Phe Glu Cys Asn Phe Ala 
    210                 215                 220                 


Leu Val Gln Tyr Gly Gly Val Ile Gln Thr Glu Phe Asp Leu Arg Asp 
225                 230                 235                 240 


Ser Gln Asp Val Met Ala Ser Leu Ala Arg Val Gln Asn Ile Thr Gln 
                245                 250                 255     


Val Gly Ser Val Thr Lys Thr Ala Ser Ala Met Gln His Val Leu Asp 
            260                 265                 270         


Ser Ile Phe Thr Ser Ser His Gly Ser Arg Arg Lys Ala Ser Lys Val 
        275                 280                 285             


Met Val Val Leu Thr Asp Gly Gly Ile Phe Glu Asp Pro Leu Asn Leu 
    290                 295                 300                 


Thr Thr Val Ile Asn Ser Pro Lys Met Gln Gly Val Glu Arg Phe Ala 
305                 310                 315                 320 


Ile Gly Val Gly Glu Glu Phe Lys Ser Ala Arg Thr Ala Arg Glu Leu 
                325                 330                 335     


Asn Leu Ile Ala Ser Asp Pro Asp Glu Thr His Ala Phe Lys Val Thr 
            340                 345                 350         


Asn Tyr Met Ala Leu Asp Gly Leu Leu Ser Lys Leu Arg Tyr Asn Ile 
        355                 360                 365             


Ile Ser Met Glu Gly Thr Val Gly Asp Ala Leu His Tyr Gln Leu Ala 
    370                 375                 380                 


Gln Ile Gly Phe Ser Ala Gln Ile Leu Asp Glu Arg Gln Val Leu Leu 
385                 390                 395                 400 


Gly Ala Val Gly Ala Phe Asp Trp Ser Gly Gly Ala Leu Leu Tyr Asp 
                405                 410                 415     


Thr Arg Ser Arg Arg Gly Arg Phe Leu Asn Gln Thr Ala Ala Ala Ala 
            420                 425                 430         


Ala Asp Ala Glu Ala Ala Gln Tyr Ser Tyr Leu Gly Tyr Ala Val Ala 
        435                 440                 445             


Val Leu His Lys Thr Cys Ser Leu Ser Tyr Val Ala Gly Ala Pro Gln 
    450                 455                 460                 


Tyr Lys His His Gly Ala Val Phe Glu Leu Gln Lys Glu Gly Arg Glu 
465                 470                 475                 480 


Ala Ser Phe Leu Pro Val Leu Glu Gly Glu Gln Met Gly Ser Tyr Phe 
                485                 490                 495     


Gly Ser Glu Leu Cys Pro Val Asp Ile Asp Met Asp Gly Ser Thr Asp 
            500                 505                 510         


Phe Leu Leu Val Ala Ala Pro Phe Tyr His Val His Gly Glu Glu Gly 
        515                 520                 525             


Arg Val Tyr Val Tyr Arg Leu Ser Glu Gln Asp Gly Ser Phe Ser Leu 
    530                 535                 540                 


Ala Arg Ile Leu Ser Gly His Pro Gly Phe Thr Asn Ala Arg Phe Gly 
545                 550                 555                 560 


Phe Ala Met Ala Ala Met Gly Asp Leu Ser Gln Asp Lys Leu Thr Asp 
                565                 570                 575     


Val Ala Ile Gly Ala Pro Leu Glu Gly Phe Gly Ala Asp Asp Gly Ala 
            580                 585                 590         


Ser Phe Gly Ser Val Tyr Ile Tyr Asn Gly His Trp Asp Gly Leu Ser 
        595                 600                 605             


Ala Ser Pro Ser Gln Arg Ile Arg Ala Ser Thr Val Ala Pro Gly Leu 
    610                 615                 620                 


Gln Tyr Phe Gly Met Ser Met Ala Gly Gly Phe Asp Ile Ser Gly Asp 
625                 630                 635                 640 


Gly Leu Ala Asp Ile Thr Val Gly Thr Leu Gly Gln Ala Val Val Phe 
                645                 650                 655     


Arg Ser Arg Pro Val Val Arg Leu Lys Val Ser Met Ala Phe Thr Pro 
            660                 665                 670         


Ser Ala Leu Pro Ile Gly Phe Asn Gly Val Val Asn Val Arg Leu Cys 
        675                 680                 685             


Phe Glu Ile Ser Ser Val Thr Thr Ala Ser Glu Ser Gly Leu Arg Glu 
    690                 695                 700                 


Ala Leu Leu Asn Phe Thr Leu Asp Val Asp Val Gly Lys Gln Arg Arg 
705                 710                 715                 720 


Arg Leu Gln Cys Ser Asp Val Arg Ser Cys Leu Gly Cys Leu Arg Glu 
                725                 730                 735     


Trp Ser Ser Gly Ser Gln Leu Cys Glu Asp Leu Leu Leu Met Pro Thr 
            740                 745                 750         


Glu Gly Glu Leu Cys Glu Glu Asp Cys Phe Ser Asn Ala Ser Val Lys 
        755                 760                 765             


Val Ser Tyr Gln Leu Gln Thr Pro Glu Gly Gln Thr Asp His Pro Gln 
    770                 775                 780                 


Pro Ile Leu Asp Arg Tyr Thr Glu Pro Phe Ala Ile Phe Gln Leu Pro 
785                 790                 795                 800 


Tyr Glu Lys Ala Cys Lys Asn Lys Leu Phe Cys Val Ala Glu Leu Gln 
                805                 810                 815     


Leu Ala Thr Thr Val Ser Gln Gln Glu Leu Val Val Gly Leu Thr Lys 
            820                 825                 830         


Glu Leu Thr Leu Asn Ile Asn Leu Thr Asn Ser Gly Glu Asp Ser Tyr 
        835                 840                 845             


Met Thr Ser Met Ala Leu Asn Tyr Pro Arg Asn Leu Gln Leu Lys Arg 
    850                 855                 860                 


Met Gln Lys Pro Pro Ser Pro Asn Ile Gln Cys Asp Asp Pro Gln Pro 
865                 870                 875                 880 


Val Ala Ser Val Leu Ile Met Asn Cys Arg Ile Gly His Pro Val Leu 
                885                 890                 895     


Lys Arg Ser Ser Ala His Val Ser Val Val Trp Gln Leu Glu Glu Asn 
            900                 905                 910         


Ala Phe Pro Asn Arg Thr Ala Asp Ile Thr Val Thr Val Thr Asn Ser 
        915                 920                 925             


Asn Glu Arg Arg Ser Leu Ala Asn Glu Thr His Thr Leu Gln Phe Arg 
    930                 935                 940                 


His Gly Phe Val Ala Val Leu Ser Lys Pro Ser Ile Met Tyr Val Asn 
945                 950                 955                 960 


Thr Gly Gln Gly Leu Ser His His Lys Glu Phe Leu Phe His Val His 
                965                 970                 975     


Gly Glu Asn Leu Phe Gly Ala Glu Tyr Gln Leu Gln Ile Cys Val Pro 
            980                 985                 990         


Thr Lys Leu Arg Gly Leu Gln Val  Ala Ala Val Lys Lys  Leu Thr Arg 
        995                 1000                 1005             


Thr Gln  Ala Ser Thr Val Cys  Thr Trp Ser Gln Glu  Arg Ala Cys 
    1010                 1015                 1020             


Ala Tyr  Ser Ser Val Gln His  Val Glu Glu Trp His  Ser Val Ser 
    1025                 1030                 1035             


Cys Val  Ile Ala Ser Asp Lys  Glu Asn Val Thr Val  Ala Ala Glu 
    1040                 1045                 1050             


Ile Ser  Trp Asp His Ser Glu  Glu Leu Leu Lys Asp  Val Thr Glu 
    1055                 1060                 1065             


Leu Gln  Ile Leu Gly Glu Ile  Ser Phe Asn Lys Ser  Leu Tyr Glu 
    1070                 1075                 1080             


Gly Leu  Asn Ala Glu Asn His  Arg Thr Lys Ile Thr  Val Val Phe 
    1085                 1090                 1095             


Leu Lys  Asp Glu Lys Tyr His  Ser 
    1100                 1105     


<210>  734
<211>  981
<212>  PRT
<213>  Homo Sapiens

<400>  734

Tyr Asn Leu Asp Val Arg Gly Ala Arg Ser Phe Ser Pro Pro Arg Ala 
1               5                   10                  15      


Gly Arg His Phe Gly Tyr Arg Val Leu Gln Val Gly Asn Gly Val Ile 
            20                  25                  30          


Val Gly Ala Pro Gly Glu Gly Asn Ser Thr Gly Ser Leu Tyr Gln Cys 
        35                  40                  45              


Gln Ser Gly Thr Gly His Cys Leu Pro Val Thr Leu Arg Gly Ser Asn 
    50                  55                  60                  


Tyr Thr Ser Lys Tyr Leu Gly Met Thr Leu Ala Thr Asp Pro Thr Asp 
65                  70                  75                  80  


Gly Ser Ile Leu Phe Ala Ala Val Gln Phe Ser Thr Ser Tyr Lys Thr 
                85                  90                  95      


Glu Phe Asp Phe Ser Asp Tyr Val Lys Arg Lys Asp Pro Asp Ala Leu 
            100                 105                 110         


Leu Lys His Val Lys His Met Leu Leu Leu Thr Asn Thr Phe Gly Ala 
        115                 120                 125             


Ile Asn Tyr Val Ala Thr Glu Val Phe Arg Glu Glu Leu Gly Ala Arg 
    130                 135                 140                 


Pro Asp Ala Thr Lys Val Leu Ile Ile Ile Thr Asp Gly Glu Ala Thr 
145                 150                 155                 160 


Asp Ser Gly Asn Ile Asp Ala Ala Lys Asp Ile Ile Arg Tyr Ile Ile 
                165                 170                 175     


Gly Ile Gly Lys His Phe Gln Thr Lys Glu Ser Gln Glu Thr Leu His 
            180                 185                 190         


Lys Phe Ala Ser Lys Pro Ala Ser Glu Phe Val Lys Ile Leu Asp Thr 
        195                 200                 205             


Phe Glu Lys Leu Lys Asp Leu Phe Thr Glu Leu Gln Lys Lys Ile Tyr 
    210                 215                 220                 


Val Ile Glu Gly Thr Ser Lys Gln Asp Leu Thr Ser Phe Asn Met Glu 
225                 230                 235                 240 


Leu Ser Ser Ser Gly Ile Ser Ala Asp Leu Ser Arg Gly His Ala Val 
                245                 250                 255     


Val Gly Ala Val Gly Ala Lys Asp Trp Ala Gly Gly Phe Leu Asp Leu 
            260                 265                 270         


Lys Ala Asp Leu Gln Asp Asp Thr Phe Ile Gly Asn Glu Pro Leu Thr 
        275                 280                 285             


Pro Glu Val Arg Ala Gly Tyr Leu Gly Tyr Thr Val Thr Trp Leu Pro 
    290                 295                 300                 


Ser Arg Gln Lys Thr Ser Leu Leu Ala Ser Gly Ala Pro Arg Tyr Gln 
305                 310                 315                 320 


His Met Gly Arg Val Leu Leu Phe Gln Glu Pro Gln Gly Gly Gly His 
                325                 330                 335     


Trp Ser Gln Val Gln Thr Ile His Gly Thr Gln Ile Gly Ser Tyr Phe 
            340                 345                 350         


Gly Gly Glu Leu Cys Gly Val Asp Val Asp Gln Asp Gly Glu Thr Glu 
        355                 360                 365             


Leu Leu Leu Ile Gly Ala Pro Leu Phe Tyr Gly Glu Gln Arg Gly Gly 
    370                 375                 380                 


Arg Val Phe Ile Tyr Gln Arg Arg Gln Leu Gly Phe Glu Glu Val Ser 
385                 390                 395                 400 


Glu Leu Gln Gly Asp Pro Gly Tyr Pro Leu Gly Arg Phe Gly Glu Ala 
                405                 410                 415     


Ile Thr Ala Leu Thr Asp Ile Asn Gly Asp Gly Leu Val Asp Val Ala 
            420                 425                 430         


Val Gly Ala Pro Leu Glu Glu Gln Gly Ala Val Tyr Ile Phe Asn Gly 
        435                 440                 445             


Arg His Gly Gly Leu Ser Pro Gln Pro Ser Gln Arg Ile Glu Gly Thr 
    450                 455                 460                 


Gln Val Leu Ser Gly Ile Gln Trp Phe Gly Arg Ser Ile His Gly Val 
465                 470                 475                 480 


Lys Asp Leu Glu Gly Asp Gly Leu Ala Asp Val Ala Val Gly Ala Glu 
                485                 490                 495     


Ser Gln Met Ile Val Leu Ser Ser Arg Pro Val Val Asp Met Val Thr 
            500                 505                 510         


Leu Met Ser Phe Ser Pro Ala Glu Ile Pro Val His Glu Val Glu Cys 
        515                 520                 525             


Ser Tyr Ser Thr Ser Asn Lys Met Lys Glu Gly Val Asn Ile Thr Ile 
    530                 535                 540                 


Cys Phe Gln Ile Lys Ser Leu Ile Pro Gln Phe Gln Gly Arg Leu Val 
545                 550                 555                 560 


Ala Asn Leu Thr Tyr Thr Leu Gln Leu Asp Gly His Arg Thr Arg Arg 
                565                 570                 575     


Arg Gly Leu Phe Pro Gly Gly Arg His Glu Leu Arg Arg Asn Ile Ala 
            580                 585                 590         


Val Thr Thr Ser Met Ser Cys Thr Asp Phe Ser Phe His Phe Pro Val 
        595                 600                 605             


Cys Val Gln Asp Leu Ile Ser Pro Ile Asn Val Ser Leu Asn Phe Ser 
    610                 615                 620                 


Leu Trp Glu Glu Glu Gly Thr Pro Arg Asp Gln Arg Ala Gly Lys Asp 
625                 630                 635                 640 


Ile Pro Pro Ile Leu Arg Pro Ser Leu His Ser Glu Thr Trp Glu Ile 
                645                 650                 655     


Pro Phe Glu Lys Asn Cys Gly Glu Asp Lys Lys Cys Glu Ala Asn Leu 
            660                 665                 670         


Arg Val Ser Phe Ser Pro Ala Arg Ser Arg Ala Leu Arg Leu Thr Ala 
        675                 680                 685             


Phe Ala Ser Leu Ser Val Glu Leu Ser Leu Ser Asn Leu Glu Glu Asp 
    690                 695                 700                 


Ala Tyr Trp Val Gln Leu Asp Leu His Phe Pro Pro Gly Leu Ser Phe 
705                 710                 715                 720 


Arg Lys Val Glu Met Leu Lys Pro His Ser Gln Ile Pro Val Ser Cys 
                725                 730                 735     


Glu Glu Leu Pro Glu Glu Ser Arg Leu Leu Ser Arg Ala Leu Ser Cys 
            740                 745                 750         


Asn Val Ser Ser Pro Ile Phe Lys Ala Gly His Ser Val Ala Leu Gln 
        755                 760                 765             


Met Met Phe Asn Thr Leu Val Asn Ser Ser Trp Gly Asp Ser Val Glu 
    770                 775                 780                 


Leu His Ala Asn Val Thr Cys Asn Asn Glu Asp Ser Asp Leu Leu Glu 
785                 790                 795                 800 


Asp Asn Ser Ala Thr Thr Ile Ile Pro Ile Leu Tyr Pro Ile Asn Ile 
                805                 810                 815     


Leu Ile Gln Asp Gln Glu Asp Ser Thr Leu Tyr Val Ser Phe Thr Pro 
            820                 825                 830         


Lys Gly Pro Lys Ile His Gln Val Lys His Met Tyr Gln Val Arg Ile 
        835                 840                 845             


Gln Pro Ser Ile His Asp His Asn Ile Pro Thr Leu Glu Ala Val Val 
    850                 855                 860                 


Gly Val Pro Gln Pro Pro Ser Glu Gly Pro Ile Thr His Gln Trp Ser 
865                 870                 875                 880 


Val Gln Met Glu Pro Pro Val Pro Cys His Tyr Glu Asp Leu Glu Arg 
                885                 890                 895     


Leu Pro Asp Ala Ala Glu Pro Cys Leu Pro Gly Ala Leu Phe Arg Cys 
            900                 905                 910         


Pro Val Val Phe Arg Gln Glu Ile Leu Val Gln Val Ile Gly Thr Leu 
        915                 920                 925             


Glu Leu Val Gly Glu Ile Glu Ala Ser Ser Met Phe Ser Leu Cys Ser 
    930                 935                 940                 


Ser Leu Ser Ile Ser Phe Asn Ser Ser Lys His Phe His Leu Tyr Gly 
945                 950                 955                 960 


Ser Asn Ala Ser Leu Ala Gln Val Val Met Lys Val Asp Val Val Tyr 
                965                 970                 975     


Glu Lys Gln Met Leu 
            980     


<210>  735
<211>  1088
<212>  PRT
<213>  Homo Sapiens

<400>  735

Phe Asn Leu Asp Thr Glu Asn Ala Met Thr Phe Gln Glu Asn Ala Arg 
1               5                   10                  15      


Gly Phe Gly Gln Ser Val Val Gln Leu Gln Gly Ser Arg Val Val Val 
            20                  25                  30          


Gly Ala Pro Gln Glu Ile Val Ala Ala Asn Gln Arg Gly Ser Leu Tyr 
        35                  40                  45              


Gln Cys Asp Tyr Ser Thr Gly Ser Cys Glu Pro Ile His Leu Gln Val 
    50                  55                  60                  


Pro Val Glu Ala Val Asn Met Ser Leu Gly Leu Ser Leu Ala Ala Thr 
65                  70                  75                  80  


Thr Ser Pro Pro Gln Leu Leu Ala Cys Gly Pro Thr Val His Gln Thr 
                85                  90                  95      


Cys Ser Glu Asn Thr Tyr Val Lys Gly Leu Cys Phe Leu Phe Gly Ser 
            100                 105                 110         


Asn Leu Arg Gln Gln Pro Gln Lys Phe Pro Glu Ala Leu Arg Gly Cys 
        115                 120                 125             


Pro Gln Glu Asp Ser Asp Ile Ala Phe Leu Ile Asp Gly Ser Gly Ser 
    130                 135                 140                 


Ile Ile Pro His Asp Phe Arg Arg Met Lys Glu Phe Val Ser Thr Val 
145                 150                 155                 160 


Met Glu Gln Leu Lys Lys Ser Lys Thr Leu Phe Ser Leu Met Gln Tyr 
                165                 170                 175     


Ser Glu Glu Phe Arg Ile His Phe Thr Phe Lys Glu Phe Gln Asn Asn 
            180                 185                 190         


Pro Asn Pro Arg Ser Leu Val Lys Pro Ile Thr Gln Leu Leu Gly Arg 
        195                 200                 205             


Thr His Thr Ala Thr Gly Ile Arg Lys Val Val Arg Glu Leu Phe Asn 
    210                 215                 220                 


Ile Thr Asn Gly Ala Arg Lys Asn Ala Phe Lys Ile Leu Val Val Ile 
225                 230                 235                 240 


Thr Asp Gly Glu Lys Phe Gly Asp Pro Leu Gly Tyr Glu Asp Val Ile 
                245                 250                 255     


Pro Glu Ala Asp Arg Glu Gly Val Ile Arg Tyr Val Ile Gly Val Gly 
            260                 265                 270         


Asp Ala Phe Arg Ser Glu Lys Ser Arg Gln Glu Leu Asn Thr Ile Ala 
        275                 280                 285             


Ser Lys Pro Pro Arg Asp His Val Phe Gln Val Asn Asn Phe Glu Ala 
    290                 295                 300                 


Leu Lys Thr Ile Gln Asn Gln Leu Arg Glu Lys Ile Phe Ala Ile Glu 
305                 310                 315                 320 


Gly Thr Gln Thr Gly Ser Ser Ser Ser Phe Glu His Glu Met Ser Gln 
                325                 330                 335     


Glu Gly Phe Ser Ala Ala Ile Thr Ser Asn Gly Pro Leu Leu Ser Thr 
            340                 345                 350         


Val Gly Ser Tyr Asp Trp Ala Gly Gly Val Phe Leu Tyr Thr Ser Lys 
        355                 360                 365             


Glu Lys Ser Thr Phe Ile Asn Met Thr Arg Val Asp Ser Asp Met Asn 
    370                 375                 380                 


Asp Ala Tyr Leu Gly Tyr Ala Ala Ala Ile Ile Leu Arg Asn Arg Val 
385                 390                 395                 400 


Gln Ser Leu Val Leu Gly Ala Pro Arg Tyr Gln His Ile Gly Leu Val 
                405                 410                 415     


Ala Met Phe Arg Gln Asn Thr Gly Met Trp Glu Ser Asn Ala Asn Val 
            420                 425                 430         


Lys Gly Thr Gln Ile Gly Ala Tyr Phe Gly Ala Ser Leu Cys Ser Val 
        435                 440                 445             


Asp Val Asp Ser Asn Gly Ser Thr Asp Leu Val Leu Ile Gly Ala Pro 
    450                 455                 460                 


His Tyr Tyr Glu Gln Thr Arg Gly Gly Gln Val Ser Val Cys Pro Leu 
465                 470                 475                 480 


Pro Arg Gly Arg Ala Arg Trp Gln Cys Asp Ala Val Leu Tyr Gly Glu 
                485                 490                 495     


Gln Gly Gln Pro Trp Gly Arg Phe Gly Ala Ala Leu Thr Val Leu Gly 
            500                 505                 510         


Asp Val Asn Gly Asp Lys Leu Thr Asp Val Ala Ile Gly Ala Pro Gly 
        515                 520                 525             


Glu Glu Asp Asn Arg Gly Ala Val Tyr Leu Phe His Gly Thr Ser Gly 
    530                 535                 540                 


Ser Gly Ile Ser Pro Ser His Ser Gln Arg Ile Ala Gly Ser Lys Leu 
545                 550                 555                 560 


Ser Pro Arg Leu Gln Tyr Phe Gly Gln Ser Leu Ser Gly Gly Gln Asp 
                565                 570                 575     


Leu Thr Met Asp Gly Leu Val Asp Leu Thr Val Gly Ala Gln Gly His 
            580                 585                 590         


Val Leu Leu Leu Arg Ser Gln Pro Val Leu Arg Val Lys Ala Ile Met 
        595                 600                 605             


Glu Phe Asn Pro Arg Glu Val Ala Arg Asn Val Phe Glu Cys Asn Asp 
    610                 615                 620                 


Gln Val Val Lys Gly Lys Glu Ala Gly Glu Val Arg Val Cys Leu His 
625                 630                 635                 640 


Val Gln Lys Ser Thr Arg Asp Arg Leu Arg Glu Gly Gln Ile Gln Ser 
                645                 650                 655     


Val Val Thr Tyr Asp Leu Ala Leu Asp Ser Gly Arg Pro His Ser Arg 
            660                 665                 670         


Ala Val Phe Asn Glu Thr Lys Asn Ser Thr Arg Arg Gln Thr Gln Val 
        675                 680                 685             


Leu Gly Leu Thr Gln Thr Cys Glu Thr Leu Lys Leu Gln Leu Pro Asn 
    690                 695                 700                 


Cys Ile Glu Asp Pro Val Ser Pro Ile Val Leu Arg Leu Asn Phe Ser 
705                 710                 715                 720 


Leu Val Gly Thr Pro Leu Ser Ala Phe Gly Asn Leu Arg Pro Val Leu 
                725                 730                 735     


Ala Glu Asp Ala Gln Arg Leu Phe Thr Ala Leu Phe Pro Phe Glu Lys 
            740                 745                 750         


Asn Cys Gly Asn Asp Asn Ile Cys Gln Asp Asp Leu Ser Ile Thr Phe 
        755                 760                 765             


Ser Phe Met Ser Leu Asp Cys Leu Val Val Gly Gly Pro Arg Glu Phe 
    770                 775                 780                 


Asn Val Thr Val Thr Val Arg Asn Asp Gly Glu Asp Ser Tyr Arg Thr 
785                 790                 795                 800 


Gln Val Thr Phe Phe Phe Pro Leu Asp Leu Ser Tyr Arg Lys Val Ser 
                805                 810                 815     


Thr Leu Gln Asn Gln Arg Ser Gln Arg Ser Trp Arg Leu Ala Cys Glu 
            820                 825                 830         


Ser Ala Ser Ser Thr Glu Val Ser Gly Val Leu Lys Ser Thr Ser Cys 
        835                 840                 845             


Ser Ile Asn His Pro Ile Phe Pro Glu Asn Ser Glu Val Thr Phe Asn 
    850                 855                 860                 


Ile Thr Phe Asp Val Asp Ser Lys Ala Ser Leu Gly Asn Lys Leu Leu 
865                 870                 875                 880 


Leu Lys Ala Asn Val Thr Ser Glu Asn Asn Met Pro Arg Thr Asn Lys 
                885                 890                 895     


Thr Glu Phe Gln Leu Glu Leu Pro Val Lys Tyr Ala Val Tyr Met Val 
            900                 905                 910         


Val Thr Ser His Gly Val Ser Thr Lys Tyr Leu Asn Phe Thr Ala Ser 
        915                 920                 925             


Glu Asn Thr Ser Arg Val Met Gln His Gln Tyr Gln Val Ser Asn Leu 
    930                 935                 940                 


Gly Gln Arg Ser Leu Pro Ile Ser Leu Val Phe Leu Val Pro Val Arg 
945                 950                 955                 960 


Leu Asn Gln Thr Val Ile Trp Asp Arg Pro Gln Val Thr Phe Ser Glu 
                965                 970                 975     


Asn Leu Ser Ser Thr Cys His Thr Lys Glu Arg Leu Pro Ser His Ser 
            980                 985                 990         


Asp Phe Leu Ala Glu Leu Arg Lys  Ala Pro Val Val Asn  Cys Ser Ile 
        995                 1000                 1005             


Ala Val  Cys Gln Arg Ile Gln  Cys Asp Ile Pro Phe  Phe Gly Ile 
    1010                 1015                 1020             


Gln Glu  Glu Phe Asn Ala Thr  Leu Lys Gly Asn Leu  Ser Phe Asp 
    1025                 1030                 1035             


Trp Tyr  Ile Lys Thr Ser His  Asn His Leu Leu Ile  Val Ser Thr 
    1040                 1045                 1050             


Ala Glu  Ile Leu Phe Asn Asp  Ser Val Phe Thr Leu  Leu Pro Gly 
    1055                 1060                 1065             


Gln Gly  Ala Phe Val Arg Ser  Gln Thr Glu Thr Lys  Val Glu Pro 
    1070                 1075                 1080             


Phe Glu  Val Pro Asn 
    1085             


<210>  736
<211>  962
<212>  PRT
<213>  Homo Sapiens

<400>  736

Phe Asn Leu Asp Val Asp Ser Pro Ala Glu Tyr Ser Gly Pro Glu Gly 
1               5                   10                  15      


Ser Tyr Phe Gly Phe Ala Val Asp Phe Phe Val Pro Ser Ala Ser Ser 
            20                  25                  30          


Arg Met Phe Leu Leu Val Gly Ala Pro Lys Ala Asn Thr Thr Gln Pro 
        35                  40                  45              


Gly Ile Val Glu Gly Gly Gln Val Leu Lys Cys Asp Trp Ser Ser Thr 
    50                  55                  60                  


Arg Arg Cys Gln Pro Ile Glu Phe Asp Ala Thr Gly Asn Arg Asp Tyr 
65                  70                  75                  80  


Ala Lys Asp Asp Pro Leu Glu Phe Lys Ser His Gln Trp Phe Gly Ala 
                85                  90                  95      


Ser Val Arg Ser Lys Gln Asp Lys Ile Leu Ala Cys Ala Pro Leu Tyr 
            100                 105                 110         


His Trp Arg Thr Glu Met Lys Gln Glu Arg Glu Pro Val Gly Thr Cys 
        115                 120                 125             


Phe Leu Gln Asp Gly Thr Lys Thr Val Glu Tyr Ala Pro Cys Arg Ser 
    130                 135                 140                 


Gln Asp Ile Asp Ala Asp Gly Gln Gly Phe Cys Gln Gly Gly Phe Ser 
145                 150                 155                 160 


Ile Asp Phe Thr Lys Ala Asp Arg Val Leu Leu Gly Gly Pro Gly Ser 
                165                 170                 175     


Phe Tyr Trp Gln Gly Gln Leu Ile Ser Asp Gln Val Ala Glu Ile Val 
            180                 185                 190         


Ser Lys Tyr Asp Pro Asn Val Tyr Ser Ile Lys Tyr Asn Asn Gln Leu 
        195                 200                 205             


Ala Thr Arg Thr Ala Gln Ala Ile Phe Asp Asp Ser Tyr Leu Gly Tyr 
    210                 215                 220                 


Ser Val Ala Val Gly Asp Phe Asn Gly Asp Gly Ile Asp Asp Phe Val 
225                 230                 235                 240 


Ser Gly Val Pro Arg Ala Ala Arg Thr Leu Gly Met Val Tyr Ile Tyr 
                245                 250                 255     


Asp Gly Lys Asn Met Ser Ser Leu Tyr Asn Phe Thr Gly Glu Gln Met 
            260                 265                 270         


Ala Ala Tyr Phe Gly Phe Ser Val Ala Ala Thr Asp Ile Asn Gly Asp 
        275                 280                 285             


Asp Tyr Ala Asp Val Phe Ile Gly Ala Pro Leu Phe Met Asp Arg Gly 
    290                 295                 300                 


Ser Asp Gly Lys Leu Gln Glu Val Gly Gln Val Ser Val Ser Leu Gln 
305                 310                 315                 320 


Arg Ala Ser Gly Asp Phe Gln Thr Thr Lys Leu Asn Gly Phe Glu Val 
                325                 330                 335     


Phe Ala Arg Phe Gly Ser Ala Ile Ala Pro Leu Gly Asp Leu Asp Gln 
            340                 345                 350         


Asp Gly Phe Asn Asp Ile Ala Ile Ala Ala Pro Tyr Gly Gly Glu Asp 
        355                 360                 365             


Lys Lys Gly Ile Val Tyr Ile Phe Asn Gly Arg Ser Thr Gly Leu Asn 
    370                 375                 380                 


Ala Val Pro Ser Gln Ile Leu Glu Gly Gln Trp Ala Ala Arg Ser Met 
385                 390                 395                 400 


Pro Pro Ser Phe Gly Tyr Ser Met Lys Gly Ala Thr Asp Ile Asp Lys 
                405                 410                 415     


Asn Gly Tyr Pro Asp Leu Ile Val Gly Ala Phe Gly Val Asp Arg Ala 
            420                 425                 430         


Ile Leu Tyr Arg Ala Arg Pro Val Ile Thr Val Asn Ala Gly Leu Glu 
        435                 440                 445             


Val Tyr Pro Ser Ile Leu Asn Gln Asp Asn Lys Thr Cys Ser Leu Pro 
    450                 455                 460                 


Gly Thr Ala Leu Lys Val Ser Cys Phe Asn Val Arg Phe Cys Leu Lys 
465                 470                 475                 480 


Ala Asp Gly Lys Gly Val Leu Pro Arg Lys Leu Asn Phe Gln Val Glu 
                485                 490                 495     


Leu Leu Leu Asp Lys Leu Lys Gln Lys Gly Ala Ile Arg Arg Ala Leu 
            500                 505                 510         


Phe Leu Tyr Ser Arg Ser Pro Ser His Ser Lys Asn Met Thr Ile Ser 
        515                 520                 525             


Arg Gly Gly Leu Met Gln Cys Glu Glu Leu Ile Ala Tyr Leu Arg Asp 
    530                 535                 540                 


Glu Ser Glu Phe Arg Asp Lys Leu Thr Pro Ile Thr Ile Phe Met Glu 
545                 550                 555                 560 


Tyr Arg Leu Asp Tyr Arg Thr Ala Ala Asp Thr Thr Gly Leu Gln Pro 
                565                 570                 575     


Ile Leu Asn Gln Phe Thr Pro Ala Asn Ile Ser Arg Gln Ala His Ile 
            580                 585                 590         


Leu Leu Asp Cys Gly Glu Asp Asn Val Cys Lys Pro Lys Leu Glu Val 
        595                 600                 605             


Ser Val Asp Ser Asp Gln Lys Lys Ile Tyr Ile Gly Asp Asp Asn Pro 
    610                 615                 620                 


Leu Thr Leu Ile Val Lys Ala Gln Asn Gln Gly Glu Gly Ala Tyr Glu 
625                 630                 635                 640 


Ala Glu Leu Ile Val Ser Ile Pro Leu Gln Ala Asp Phe Ile Gly Val 
                645                 650                 655     


Val Arg Asn Asn Glu Ala Leu Ala Arg Leu Ser Cys Ala Phe Lys Thr 
            660                 665                 670         


Glu Asn Gln Thr Arg Gln Val Val Cys Asp Leu Gly Asn Pro Met Lys 
        675                 680                 685             


Ala Gly Thr Gln Leu Leu Ala Gly Leu Arg Phe Ser Val His Gln Gln 
    690                 695                 700                 


Ser Glu Met Asp Thr Ser Val Lys Phe Asp Leu Gln Ile Gln Ser Ser 
705                 710                 715                 720 


Asn Leu Phe Asp Lys Val Ser Pro Val Val Ser His Lys Val Asp Leu 
                725                 730                 735     


Ala Val Leu Ala Ala Val Glu Ile Arg Gly Val Ser Ser Pro Asp His 
            740                 745                 750         


Ile Phe Leu Pro Ile Pro Asn Trp Glu His Lys Glu Asn Pro Glu Thr 
        755                 760                 765             


Glu Glu Asp Val Gly Pro Val Val Gln His Ile Tyr Glu Leu Arg Asn 
    770                 775                 780                 


Asn Gly Pro Ser Ser Phe Ser Lys Ala Met Leu His Leu Gln Trp Pro 
785                 790                 795                 800 


Tyr Lys Tyr Asn Asn Asn Thr Leu Leu Tyr Ile Leu His Tyr Asp Ile 
                805                 810                 815     


Asp Gly Pro Met Asn Cys Thr Ser Asp Met Glu Ile Asn Pro Leu Arg 
            820                 825                 830         


Ile Lys Ile Ser Ser Leu Gln Thr Thr Glu Lys Asn Asp Thr Val Ala 
        835                 840                 845             


Gly Gln Gly Glu Arg Asp His Leu Ile Thr Lys Arg Asp Leu Ala Leu 
    850                 855                 860                 


Ser Glu Gly Asp Ile His Thr Leu Gly Cys Gly Val Ala Gln Cys Leu 
865                 870                 875                 880 


Lys Ile Val Cys Gln Val Gly Arg Leu Asp Arg Gly Lys Ser Ala Ile 
                885                 890                 895     


Leu Tyr Val Lys Ser Leu Leu Trp Thr Glu Thr Phe Met Asn Lys Glu 
            900                 905                 910         


Asn Gln Asn His Ser Tyr Ser Leu Lys Ser Ser Ala Ser Phe Asn Val 
        915                 920                 925             


Ile Glu Phe Pro Tyr Lys Asn Leu Pro Ile Glu Asp Ile Thr Asn Ser 
    930                 935                 940                 


Thr Leu Val Thr Thr Asn Val Thr Trp Gly Ile Gln Pro Ala Pro Met 
945                 950                 955                 960 


Pro Val 
        


<210>  737
<211>  1088
<212>  PRT
<213>  Homo Sapiens

<400>  737

Phe Asn Leu Asp Thr Glu Glu Leu Thr Ala Phe Arg Val Asp Ser Ala 
1               5                   10                  15      


Gly Phe Gly Asp Ser Val Val Gln Tyr Ala Asn Ser Trp Val Val Val 
            20                  25                  30          


Gly Ala Pro Gln Lys Ile Thr Ala Ala Asn Gln Thr Gly Gly Leu Tyr 
        35                  40                  45              


Gln Cys Gly Tyr Ser Thr Gly Ala Cys Glu Pro Ile Gly Leu Gln Val 
    50                  55                  60                  


Pro Pro Glu Ala Val Asn Met Ser Leu Gly Leu Ser Leu Ala Ser Thr 
65                  70                  75                  80  


Thr Ser Pro Ser Gln Leu Leu Ala Cys Gly Pro Thr Val His His Glu 
                85                  90                  95      


Cys Gly Arg Asn Met Tyr Leu Thr Gly Leu Cys Phe Leu Leu Gly Pro 
            100                 105                 110         


Thr Gln Leu Thr Gln Arg Leu Pro Val Ser Arg Gln Glu Cys Pro Arg 
        115                 120                 125             


Gln Glu Gln Asp Ile Val Phe Leu Ile Asp Gly Ser Gly Ser Ile Ser 
    130                 135                 140                 


Ser Arg Asn Phe Ala Thr Met Met Asn Phe Val Arg Ala Val Ile Ser 
145                 150                 155                 160 


Gln Phe Gln Arg Pro Ser Thr Gln Phe Ser Leu Met Gln Phe Ser Asn 
                165                 170                 175     


Lys Phe Gln Thr His Phe Thr Phe Glu Glu Phe Arg Arg Ser Ser Asn 
            180                 185                 190         


Pro Leu Ser Leu Leu Ala Ser Val His Gln Leu Gln Gly Phe Thr Tyr 
        195                 200                 205             


Thr Ala Thr Ala Ile Gln Asn Val Val His Arg Leu Phe His Ala Ser 
    210                 215                 220                 


Tyr Gly Ala Arg Arg Asp Ala Ala Lys Ile Leu Ile Val Ile Thr Asp 
225                 230                 235                 240 


Gly Lys Lys Glu Gly Asp Ser Leu Asp Tyr Lys Asp Val Ile Pro Met 
                245                 250                 255     


Ala Asp Ala Ala Gly Ile Ile Arg Tyr Ala Ile Gly Val Gly Leu Ala 
            260                 265                 270         


Phe Gln Asn Arg Asn Ser Trp Lys Glu Leu Asn Asp Ile Ala Ser Lys 
        275                 280                 285             


Pro Ser Gln Glu His Ile Phe Lys Val Glu Asp Phe Asp Ala Leu Lys 
    290                 295                 300                 


Asp Ile Gln Asn Gln Leu Lys Glu Lys Ile Phe Ala Ile Glu Gly Thr 
305                 310                 315                 320 


Glu Thr Thr Ser Ser Ser Ser Phe Glu Leu Glu Met Ala Gln Glu Gly 
                325                 330                 335     


Phe Ser Ala Val Phe Thr Pro Asp Gly Pro Val Leu Gly Ala Val Gly 
            340                 345                 350         


Ser Phe Thr Trp Ser Gly Gly Ala Phe Leu Tyr Pro Pro Asn Met Ser 
        355                 360                 365             


Pro Thr Phe Ile Asn Met Ser Gln Glu Asn Val Asp Met Arg Asp Ser 
    370                 375                 380                 


Tyr Leu Gly Tyr Ser Thr Glu Leu Ala Leu Trp Lys Gly Val Gln Ser 
385                 390                 395                 400 


Leu Val Leu Gly Ala Pro Arg Tyr Gln His Thr Gly Lys Ala Val Ile 
                405                 410                 415     


Phe Thr Gln Val Ser Arg Gln Trp Arg Met Lys Ala Glu Val Thr Gly 
            420                 425                 430         


Thr Gln Ile Gly Ser Tyr Phe Gly Ala Ser Leu Cys Ser Val Asp Val 
        435                 440                 445             


Asp Ser Asp Gly Ser Thr Asp Leu Val Leu Ile Gly Ala Pro His Tyr 
    450                 455                 460                 


Tyr Glu Gln Thr Arg Gly Gly Gln Val Ser Val Cys Pro Leu Pro Arg 
465                 470                 475                 480 


Gly Trp Arg Arg Trp Trp Cys Asp Ala Val Leu Tyr Gly Glu Gln Gly 
                485                 490                 495     


His Pro Trp Gly Arg Phe Gly Ala Ala Leu Thr Val Leu Gly Asp Val 
            500                 505                 510         


Asn Gly Asp Lys Leu Thr Asp Val Val Ile Gly Ala Pro Gly Glu Lys 
        515                 520                 525             


Glu Asn Arg Gly Ala Val Tyr Leu Phe His Gly Val Leu Gly Pro Ser 
    530                 535                 540                 


Ile Ser Pro Ser His Ser Gln Arg Ile Ala Gly Ser Gln Leu Ser Ser 
545                 550                 555                 560 


Arg Leu Gln Tyr Phe Gly Gln Ala Leu Ser Gly Gly Gln Asp Leu Thr 
                565                 570                 575     


Gln Asp Gly Leu Val Asp Leu Ala Val Gly Ala Arg Gly Gln Val Leu 
            580                 585                 590         


Leu Leu Arg Thr Arg Pro Val Leu Trp Val Gly Val Ser Met Gln Phe 
        595                 600                 605             


Ile Pro Ala Glu Ile Pro Arg Ser Ala Phe Glu Cys Arg Glu Gln Val 
    610                 615                 620                 


Val Ser Glu Gln Thr Leu Val Gln Ser Asn Ile Cys Leu Tyr Ile Asp 
625                 630                 635                 640 


Lys Arg Ser Lys Asn Leu Leu Gly Ser Arg Asp Leu Gln Ser Ser Val 
                645                 650                 655     


Thr Leu Asp Leu Ala Leu Asp Pro Gly Arg Leu Ser Pro Arg Ala Thr 
            660                 665                 670         


Phe Gln Glu Thr Lys Asn Arg Ser Leu Ser Arg Val Arg Val Leu Gly 
        675                 680                 685             


Leu Lys Ala His Cys Glu Asn Phe Asn Leu Leu Leu Pro Ser Cys Val 
    690                 695                 700                 


Glu Asp Ser Val Thr Pro Ile Thr Leu Arg Leu Asn Phe Thr Leu Val 
705                 710                 715                 720 


Gly Lys Pro Leu Leu Ala Phe Arg Asn Leu Arg Pro Met Leu Ala Ala 
                725                 730                 735     


Asp Ala Gln Arg Tyr Phe Thr Ala Ser Leu Pro Phe Glu Lys Asn Cys 
            740                 745                 750         


Gly Ala Asp His Ile Cys Gln Asp Asn Leu Gly Ile Ser Phe Ser Phe 
        755                 760                 765             


Pro Gly Leu Lys Ser Leu Leu Val Gly Ser Asn Leu Glu Leu Asn Ala 
    770                 775                 780                 


Glu Val Met Val Trp Asn Asp Gly Glu Asp Ser Tyr Gly Thr Thr Val 
785                 790                 795                 800 


Thr Phe Ser His Pro Ala Gly Leu Ser Tyr Arg Tyr Val Ala Glu Gly 
                805                 810                 815     


Gln Lys Gln Gly Gln Leu Arg Ser Leu His Leu Thr Cys Asp Ser Ala 
            820                 825                 830         


Pro Val Gly Ser Gln Gly Thr Trp Ser Thr Ser Cys Arg Ile Asn His 
        835                 840                 845             


Leu Ile Phe Arg Gly Gly Ala Gln Ile Thr Phe Leu Ala Thr Phe Asp 
    850                 855                 860                 


Val Ser Pro Lys Ala Val Leu Gly Asp Arg Leu Leu Leu Thr Ala Asn 
865                 870                 875                 880 


Val Ser Ser Glu Asn Asn Thr Pro Arg Thr Ser Lys Thr Thr Phe Gln 
                885                 890                 895     


Leu Glu Leu Pro Val Lys Tyr Ala Val Tyr Thr Val Val Ser Ser His 
            900                 905                 910         


Glu Gln Phe Thr Lys Tyr Leu Asn Phe Ser Glu Ser Glu Glu Lys Glu 
        915                 920                 925             


Ser His Val Ala Met His Arg Tyr Gln Val Asn Asn Leu Gly Gln Arg 
    930                 935                 940                 


Asp Leu Pro Val Ser Ile Asn Phe Trp Val Pro Val Glu Leu Asn Gln 
945                 950                 955                 960 


Glu Ala Val Trp Met Asp Val Glu Val Ser His Pro Gln Asn Pro Ser 
                965                 970                 975     


Leu Arg Cys Ser Ser Glu Lys Ile Ala Pro Pro Ala Ser Asp Phe Leu 
            980                 985                 990         


Ala His Ile Gln Lys Asn Pro Val  Leu Asp Cys Ser Ile  Ala Gly Cys 
        995                 1000                 1005             


Leu Arg  Phe Arg Cys Asp Val  Pro Ser Phe Ser Val  Gln Glu Glu 
    1010                 1015                 1020             


Leu Asp  Phe Thr Leu Lys Gly  Asn Leu Ser Phe Gly  Trp Val Arg 
    1025                 1030                 1035             


Gln Ile  Leu Gln Lys Lys Val  Ser Val Val Ser Val  Ala Glu Ile 
    1040                 1045                 1050             


Thr Phe  Asp Thr Ser Val Tyr  Ser Gln Leu Pro Gly  Gln Glu Ala 
    1055                 1060                 1065             


Phe Met  Arg Ala Gln Thr Thr  Thr Val Leu Glu Lys  Tyr Lys Val 
    1070                 1075                 1080             


His Asn  Pro Thr Pro 
    1085             


<210>  738
<211>  708
<212>  PRT
<213>  Homo Sapiens

<400>  738

Gln Thr Asp Glu Asn Arg Cys Leu Lys Ala Asn Ala Lys Ser Cys Gly 
1               5                   10                  15      


Glu Cys Ile Gln Ala Gly Pro Asn Cys Gly Trp Cys Thr Asn Ser Thr 
            20                  25                  30          


Phe Leu Gln Glu Gly Met Pro Thr Ser Ala Arg Cys Asp Asp Leu Glu 
        35                  40                  45              


Ala Leu Lys Lys Lys Gly Cys Pro Pro Asp Asp Ile Glu Asn Pro Arg 
    50                  55                  60                  


Gly Ser Lys Asp Ile Lys Lys Asn Lys Asn Val Thr Asn Arg Ser Lys 
65                  70                  75                  80  


Gly Thr Ala Glu Lys Leu Lys Pro Glu Asp Ile Thr Gln Ile Gln Pro 
                85                  90                  95      


Gln Gln Leu Val Leu Arg Leu Arg Ser Gly Glu Pro Gln Thr Phe Thr 
            100                 105                 110         


Leu Lys Phe Lys Arg Ala Glu Asp Tyr Pro Ile Asp Leu Tyr Tyr Leu 
        115                 120                 125             


Met Asp Leu Ser Tyr Ser Met Lys Asp Asp Leu Glu Asn Val Lys Ser 
    130                 135                 140                 


Leu Gly Thr Asp Leu Met Asn Glu Met Arg Arg Ile Thr Ser Asp Phe 
145                 150                 155                 160 


Arg Ile Gly Phe Gly Ser Phe Val Glu Lys Thr Val Met Pro Tyr Ile 
                165                 170                 175     


Ser Thr Thr Pro Ala Lys Leu Arg Asn Pro Cys Thr Ser Glu Gln Asn 
            180                 185                 190         


Cys Thr Ser Pro Phe Ser Tyr Lys Asn Val Leu Ser Leu Thr Asn Lys 
        195                 200                 205             


Gly Glu Val Phe Asn Glu Leu Val Gly Lys Gln Arg Ile Ser Gly Asn 
    210                 215                 220                 


Leu Asp Ser Pro Glu Gly Gly Phe Asp Ala Ile Met Gln Val Ala Val 
225                 230                 235                 240 


Cys Gly Ser Leu Ile Gly Trp Arg Asn Val Thr Arg Leu Leu Val Phe 
                245                 250                 255     


Ser Thr Asp Ala Gly Phe His Phe Ala Gly Asp Gly Lys Leu Gly Gly 
            260                 265                 270         


Ile Val Leu Pro Asn Asp Gly Gln Cys His Leu Glu Asn Asn Met Tyr 
        275                 280                 285             


Thr Met Ser His Tyr Tyr Asp Tyr Pro Ser Ile Ala His Leu Val Gln 
    290                 295                 300                 


Lys Leu Ser Glu Asn Asn Ile Gln Thr Ile Phe Ala Val Thr Glu Glu 
305                 310                 315                 320 


Phe Gln Pro Val Tyr Lys Glu Leu Lys Asn Leu Ile Pro Lys Ser Ala 
                325                 330                 335     


Val Gly Thr Leu Ser Ala Asn Ser Ser Asn Val Ile Gln Leu Ile Ile 
            340                 345                 350         


Asp Ala Tyr Asn Ser Leu Ser Ser Glu Val Ile Leu Glu Asn Gly Lys 
        355                 360                 365             


Leu Ser Glu Gly Val Thr Ile Ser Tyr Lys Ser Tyr Cys Lys Asn Gly 
    370                 375                 380                 


Val Asn Gly Thr Gly Glu Asn Gly Arg Lys Cys Ser Asn Ile Ser Ile 
385                 390                 395                 400 


Gly Asp Glu Val Gln Phe Glu Ile Ser Ile Thr Ser Asn Lys Cys Pro 
                405                 410                 415     


Lys Lys Asp Ser Asp Ser Phe Lys Ile Arg Pro Leu Gly Phe Thr Glu 
            420                 425                 430         


Glu Val Glu Val Ile Leu Gln Tyr Ile Cys Glu Cys Glu Cys Gln Ser 
        435                 440                 445             


Glu Gly Ile Pro Glu Ser Pro Lys Cys His Glu Gly Asn Gly Thr Phe 
    450                 455                 460                 


Glu Cys Gly Ala Cys Arg Cys Asn Glu Gly Arg Val Gly Arg His Cys 
465                 470                 475                 480 


Glu Cys Ser Thr Asp Glu Val Asn Ser Glu Asp Met Asp Ala Tyr Cys 
                485                 490                 495     


Arg Lys Glu Asn Ser Ser Glu Ile Cys Ser Asn Asn Gly Glu Cys Val 
            500                 505                 510         


Cys Gly Gln Cys Val Cys Arg Lys Arg Asp Asn Thr Asn Glu Ile Tyr 
        515                 520                 525             


Ser Gly Lys Phe Cys Glu Cys Asp Asn Phe Asn Cys Asp Arg Ser Asn 
    530                 535                 540                 


Gly Leu Ile Cys Gly Gly Asn Gly Val Cys Lys Cys Arg Val Cys Glu 
545                 550                 555                 560 


Cys Asn Pro Asn Tyr Thr Gly Ser Ala Cys Asp Cys Ser Leu Asp Thr 
                565                 570                 575     


Ser Thr Cys Glu Ala Ser Asn Gly Gln Ile Cys Asn Gly Arg Gly Ile 
            580                 585                 590         


Cys Glu Cys Gly Val Cys Lys Cys Thr Asp Pro Lys Phe Gln Gly Gln 
        595                 600                 605             


Thr Cys Glu Met Cys Gln Thr Cys Leu Gly Val Cys Ala Glu His Lys 
    610                 615                 620                 


Glu Cys Val Gln Cys Arg Ala Phe Asn Lys Gly Glu Lys Lys Asp Thr 
625                 630                 635                 640 


Cys Thr Gln Glu Cys Ser Tyr Phe Asn Ile Thr Lys Val Glu Ser Arg 
                645                 650                 655     


Asp Lys Leu Pro Gln Pro Val Gln Pro Asp Pro Val Ser His Cys Lys 
            660                 665                 670         


Glu Lys Asp Val Asp Asp Cys Trp Phe Tyr Phe Thr Tyr Ser Val Asn 
        675                 680                 685             


Gly Asn Asn Glu Val Met Val His Val Val Glu Asn Pro Glu Cys Pro 
    690                 695                 700                 


Thr Gly Pro Asp 
705             


<210>  739
<211>  678
<212>  PRT
<213>  Homo Sapiens

<400>  739

Gln Glu Cys Thr Lys Phe Lys Val Ser Ser Cys Arg Glu Cys Ile Glu 
1               5                   10                  15      


Ser Gly Pro Gly Cys Thr Trp Cys Gln Lys Leu Asn Phe Thr Gly Pro 
            20                  25                  30          


Gly Asp Pro Asp Ser Ile Arg Cys Asp Thr Arg Pro Gln Leu Leu Met 
        35                  40                  45              


Arg Gly Cys Ala Ala Asp Asp Ile Met Asp Pro Thr Ser Leu Ala Glu 
    50                  55                  60                  


Thr Gln Glu Asp His Asn Gly Gly Gln Lys Gln Leu Ser Pro Gln Lys 
65                  70                  75                  80  


Val Thr Leu Tyr Leu Arg Pro Gly Gln Ala Ala Ala Phe Asn Val Thr 
                85                  90                  95      


Phe Arg Arg Ala Lys Gly Tyr Pro Ile Asp Leu Tyr Tyr Leu Met Asp 
            100                 105                 110         


Leu Ser Tyr Ser Met Leu Asp Asp Leu Arg Asn Val Lys Lys Leu Gly 
        115                 120                 125             


Gly Asp Leu Leu Arg Ala Leu Asn Glu Ile Thr Glu Ser Gly Arg Ile 
    130                 135                 140                 


Gly Phe Gly Ser Phe Val Asp Lys Thr Val Leu Pro Phe Val Asn Thr 
145                 150                 155                 160 


His Pro Asp Lys Leu Arg Asn Pro Cys Pro Asn Lys Glu Lys Glu Cys 
                165                 170                 175     


Gln Pro Pro Phe Ala Phe Arg His Val Leu Lys Leu Thr Asn Asn Ser 
            180                 185                 190         


Asn Gln Phe Gln Thr Glu Val Gly Lys Gln Leu Ile Ser Gly Asn Leu 
        195                 200                 205             


Asp Ala Pro Glu Gly Gly Leu Asp Ala Met Met Gln Val Ala Ala Cys 
    210                 215                 220                 


Pro Glu Glu Ile Gly Trp Arg Asn Val Thr Arg Leu Leu Val Phe Ala 
225                 230                 235                 240 


Thr Asp Asp Gly Phe His Phe Ala Gly Asp Gly Lys Leu Gly Ala Ile 
                245                 250                 255     


Leu Thr Pro Asn Asp Gly Arg Cys His Leu Glu Asp Asn Leu Tyr Lys 
            260                 265                 270         


Arg Ser Asn Glu Phe Asp Tyr Pro Ser Val Gly Gln Leu Ala His Lys 
        275                 280                 285             


Leu Ala Glu Asn Asn Ile Gln Pro Ile Phe Ala Val Thr Ser Arg Met 
    290                 295                 300                 


Val Lys Thr Tyr Glu Lys Leu Thr Glu Ile Ile Pro Lys Ser Ala Val 
305                 310                 315                 320 


Gly Glu Leu Ser Glu Asp Ser Ser Asn Val Val His Leu Ile Lys Asn 
                325                 330                 335     


Ala Tyr Asn Lys Leu Ser Ser Arg Val Phe Leu Asp His Asn Ala Leu 
            340                 345                 350         


Pro Asp Thr Leu Lys Val Thr Tyr Asp Ser Phe Cys Ser Asn Gly Val 
        355                 360                 365             


Thr His Arg Asn Gln Pro Arg Gly Asp Cys Asp Gly Val Gln Ile Asn 
    370                 375                 380                 


Val Pro Ile Thr Phe Gln Val Lys Val Thr Ala Thr Glu Cys Ile Gln 
385                 390                 395                 400 


Glu Gln Ser Phe Val Ile Arg Ala Leu Gly Phe Thr Asp Ile Val Thr 
                405                 410                 415     


Val Gln Val Leu Pro Gln Cys Glu Cys Arg Cys Arg Asp Gln Ser Arg 
            420                 425                 430         


Asp Arg Ser Leu Cys His Gly Lys Gly Phe Leu Glu Cys Gly Ile Cys 
        435                 440                 445             


Arg Cys Asp Thr Gly Tyr Ile Gly Lys Asn Cys Glu Cys Gln Thr Gln 
    450                 455                 460                 


Gly Arg Ser Ser Gln Glu Leu Glu Gly Ser Cys Arg Lys Asp Asn Asn 
465                 470                 475                 480 


Ser Ile Ile Cys Ser Gly Leu Gly Asp Cys Val Cys Gly Gln Cys Leu 
                485                 490                 495     


Cys His Thr Ser Asp Val Pro Gly Lys Leu Ile Tyr Gly Gln Tyr Cys 
            500                 505                 510         


Glu Cys Asp Thr Ile Asn Cys Glu Arg Tyr Asn Gly Gln Val Cys Gly 
        515                 520                 525             


Gly Pro Gly Arg Gly Leu Cys Phe Cys Gly Lys Cys Arg Cys His Pro 
    530                 535                 540                 


Gly Phe Glu Gly Ser Ala Cys Gln Cys Glu Arg Thr Thr Glu Gly Cys 
545                 550                 555                 560 


Leu Asn Pro Arg Arg Val Glu Cys Ser Gly Arg Gly Arg Cys Arg Cys 
                565                 570                 575     


Asn Val Cys Glu Cys His Ser Gly Tyr Gln Leu Pro Leu Cys Gln Glu 
            580                 585                 590         


Cys Pro Gly Cys Pro Ser Pro Cys Gly Lys Tyr Ile Ser Cys Ala Glu 
        595                 600                 605             


Cys Leu Lys Phe Glu Lys Gly Pro Phe Gly Lys Asn Cys Ser Ala Ala 
    610                 615                 620                 


Cys Pro Gly Leu Gln Leu Ser Asn Asn Pro Val Lys Gly Arg Thr Cys 
625                 630                 635                 640 


Lys Glu Arg Asp Ser Glu Gly Cys Trp Val Ala Tyr Thr Leu Glu Gln 
                645                 650                 655     


Gln Asp Gly Met Asp Arg Tyr Leu Ile Tyr Val Asp Glu Ser Arg Glu 
            660                 665                 670         


Cys Val Ala Gly Pro Asn 
        675             


<210>  740
<211>  692
<212>  PRT
<213>  Homo Sapiens

<400>  740

Gly Pro Asn Ile Cys Thr Thr Arg Gly Val Ser Ser Cys Gln Gln Cys 
1               5                   10                  15      


Leu Ala Val Ser Pro Met Cys Ala Trp Cys Ser Asp Glu Ala Leu Pro 
            20                  25                  30          


Leu Gly Ser Pro Arg Cys Asp Leu Lys Glu Asn Leu Leu Lys Asp Asn 
        35                  40                  45              


Cys Ala Pro Glu Ser Ile Glu Phe Pro Val Ser Glu Ala Arg Val Leu 
    50                  55                  60                  


Glu Asp Arg Pro Leu Ser Asp Lys Gly Ser Gly Asp Ser Ser Gln Val 
65                  70                  75                  80  


Thr Gln Val Ser Pro Gln Arg Ile Ala Leu Arg Leu Arg Pro Asp Asp 
                85                  90                  95      


Ser Lys Asn Phe Ser Ile Gln Val Arg Gln Val Glu Asp Tyr Pro Val 
            100                 105                 110         


Asp Ile Tyr Tyr Leu Met Asp Leu Ser Tyr Ser Met Lys Asp Asp Leu 
        115                 120                 125             


Trp Ser Ile Gln Asn Leu Gly Thr Lys Leu Ala Thr Gln Met Arg Lys 
    130                 135                 140                 


Leu Thr Ser Asn Leu Arg Ile Gly Phe Gly Ala Phe Val Asp Lys Pro 
145                 150                 155                 160 


Val Ser Pro Tyr Met Tyr Ile Ser Pro Pro Glu Ala Leu Glu Asn Pro 
                165                 170                 175     


Cys Tyr Asp Met Lys Thr Thr Cys Leu Pro Met Phe Gly Tyr Lys His 
            180                 185                 190         


Val Leu Thr Leu Thr Asp Gln Val Thr Arg Phe Asn Glu Glu Val Lys 
        195                 200                 205             


Lys Gln Ser Val Ser Arg Asn Arg Asp Ala Pro Glu Gly Gly Phe Asp 
    210                 215                 220                 


Ala Ile Met Gln Ala Thr Val Cys Asp Glu Lys Ile Gly Trp Arg Asn 
225                 230                 235                 240 


Asp Ala Ser His Leu Leu Val Phe Thr Thr Asp Ala Lys Thr His Ile 
                245                 250                 255     


Ala Leu Asp Gly Arg Leu Ala Gly Ile Val Gln Pro Asn Asp Gly Gln 
            260                 265                 270         


Cys His Val Gly Ser Asp Asn His Tyr Ser Ala Ser Thr Thr Met Asp 
        275                 280                 285             


Tyr Pro Ser Leu Gly Leu Met Thr Glu Lys Leu Ser Gln Lys Asn Ile 
    290                 295                 300                 


Asn Leu Ile Phe Ala Val Thr Glu Asn Val Val Asn Leu Tyr Gln Asn 
305                 310                 315                 320 


Tyr Ser Glu Leu Ile Pro Gly Thr Thr Val Gly Val Leu Ser Met Asp 
                325                 330                 335     


Ser Ser Asn Val Leu Gln Leu Ile Val Asp Ala Tyr Gly Lys Ile Arg 
            340                 345                 350         


Ser Lys Val Glu Leu Glu Val Arg Asp Leu Pro Glu Glu Leu Ser Leu 
        355                 360                 365             


Ser Phe Asn Ala Thr Cys Leu Asn Asn Glu Val Ile Pro Gly Leu Lys 
    370                 375                 380                 


Ser Cys Met Gly Leu Lys Ile Gly Asp Thr Val Ser Phe Ser Ile Glu 
385                 390                 395                 400 


Ala Lys Val Arg Gly Cys Pro Gln Glu Lys Glu Lys Ser Phe Thr Ile 
                405                 410                 415     


Lys Pro Val Gly Phe Lys Asp Ser Leu Ile Val Gln Val Thr Phe Asp 
            420                 425                 430         


Cys Asp Cys Ala Cys Gln Ala Gln Ala Glu Pro Asn Ser His Arg Cys 
        435                 440                 445             


Asn Asn Gly Asn Gly Thr Phe Glu Cys Gly Val Cys Arg Cys Gly Pro 
    450                 455                 460                 


Gly Trp Leu Gly Ser Gln Cys Glu Cys Ser Glu Glu Asp Tyr Arg Pro 
465                 470                 475                 480 


Ser Gln Gln Asp Glu Cys Ser Pro Arg Glu Gly Gln Pro Val Cys Ser 
                485                 490                 495     


Gln Arg Gly Glu Cys Leu Cys Gly Gln Cys Val Cys His Ser Ser Asp 
            500                 505                 510         


Phe Gly Lys Ile Thr Gly Lys Tyr Cys Glu Cys Asp Asp Phe Ser Cys 
        515                 520                 525             


Val Arg Tyr Lys Gly Glu Met Cys Ser Gly His Gly Gln Cys Ser Cys 
    530                 535                 540                 


Gly Asp Cys Leu Cys Asp Ser Asp Trp Thr Gly Tyr Tyr Cys Asn Cys 
545                 550                 555                 560 


Thr Thr Arg Thr Asp Thr Cys Met Ser Ser Asn Gly Leu Leu Cys Ser 
                565                 570                 575     


Gly Arg Gly Lys Cys Glu Cys Gly Ser Cys Val Cys Ile Gln Pro Gly 
            580                 585                 590         


Ser Tyr Gly Asp Thr Cys Glu Lys Cys Pro Thr Cys Pro Asp Ala Cys 
        595                 600                 605             


Thr Phe Lys Lys Glu Cys Val Glu Cys Lys Lys Phe Asp Arg Gly Ala 
    610                 615                 620                 


Leu His Asp Glu Asn Thr Cys Asn Arg Tyr Cys Arg Asp Glu Ile Glu 
625                 630                 635                 640 


Ser Val Lys Glu Leu Lys Asp Thr Gly Lys Asp Ala Val Asn Cys Thr 
                645                 650                 655     


Tyr Lys Asn Glu Asp Asp Cys Val Val Arg Phe Gln Tyr Tyr Glu Asp 
            660                 665                 670         


Ser Ser Gly Lys Ser Ile Leu Tyr Val Val Glu Glu Pro Glu Cys Pro 
        675                 680                 685             


Lys Gly Pro Asp 
    690         


<210>  741
<211>  696
<212>  PRT
<213>  Homo Sapiens

<400>  741

Gly Leu Asn Ile Cys Thr Ser Gly Ser Ala Thr Ser Cys Glu Glu Cys 
1               5                   10                  15      


Leu Leu Ile His Pro Lys Cys Ala Trp Cys Ser Lys Glu Asp Phe Gly 
            20                  25                  30          


Ser Pro Arg Ser Ile Thr Ser Arg Cys Asp Leu Arg Ala Asn Leu Val 
        35                  40                  45              


Lys Asn Gly Cys Gly Gly Glu Ile Glu Ser Pro Ala Ser Ser Phe His 
    50                  55                  60                  


Val Leu Arg Ser Leu Pro Leu Ser Ser Lys Gly Ser Gly Ser Ala Gly 
65                  70                  75                  80  


Trp Asp Val Ile Gln Met Thr Pro Gln Glu Ile Ala Val Asn Leu Arg 
                85                  90                  95      


Pro Gly Asp Lys Thr Thr Phe Gln Leu Gln Val Arg Gln Val Glu Asp 
            100                 105                 110         


Tyr Pro Val Asp Leu Tyr Tyr Leu Met Asp Leu Ser Leu Ser Met Lys 
        115                 120                 125             


Asp Asp Leu Asp Asn Ile Arg Ser Leu Gly Thr Lys Leu Ala Glu Glu 
    130                 135                 140                 


Met Arg Lys Leu Thr Ser Asn Phe Arg Leu Gly Phe Gly Ser Phe Val 
145                 150                 155                 160 


Asp Lys Asp Ile Ser Pro Phe Ser Tyr Thr Ala Pro Arg Tyr Gln Thr 
                165                 170                 175     


Asn Pro Cys Ile Gly Tyr Lys Leu Phe Pro Asn Cys Val Pro Ser Phe 
            180                 185                 190         


Gly Phe Arg His Leu Leu Pro Leu Thr Asp Arg Val Asp Ser Phe Asn 
        195                 200                 205             


Glu Glu Val Arg Lys Gln Arg Val Ser Arg Asn Arg Asp Ala Pro Glu 
    210                 215                 220                 


Gly Gly Phe Asp Ala Val Leu Gln Ala Ala Val Cys Lys Glu Lys Ile 
225                 230                 235                 240 


Gly Trp Arg Lys Asp Ala Leu His Leu Leu Val Phe Thr Thr Asp Asp 
                245                 250                 255     


Val Pro His Ile Ala Leu Asp Gly Lys Leu Gly Gly Leu Val Gln Pro 
            260                 265                 270         


His Asp Gly Gln Cys His Leu Asn Glu Ala Asn Glu Tyr Thr Ala Ser 
        275                 280                 285             


Asn Gln Met Asp Tyr Pro Ser Leu Ala Leu Leu Gly Glu Lys Leu Ala 
    290                 295                 300                 


Glu Asn Asn Ile Asn Leu Ile Phe Ala Val Thr Lys Asn His Tyr Met 
305                 310                 315                 320 


Leu Tyr Lys Asn Phe Thr Ala Leu Ile Pro Gly Thr Thr Val Glu Ile 
                325                 330                 335     


Leu Asp Gly Asp Ser Lys Asn Ile Ile Gln Leu Ile Ile Asn Ala Tyr 
            340                 345                 350         


Asn Ser Ile Arg Ser Lys Val Glu Leu Ser Val Trp Asp Gln Pro Glu 
        355                 360                 365             


Asp Leu Asn Leu Phe Phe Thr Ala Thr Cys Gln Asp Gly Val Ser Tyr 
    370                 375                 380                 


Pro Gly Gln Arg Lys Cys Glu Gly Leu Lys Ile Gly Asp Thr Ala Ser 
385                 390                 395                 400 


Phe Glu Val Ser Leu Glu Ala Arg Ser Cys Pro Ser Arg His Thr Glu 
                405                 410                 415     


His Val Phe Ala Leu Arg Pro Val Gly Phe Arg Asp Ser Leu Glu Val 
            420                 425                 430         


Gly Val Thr Tyr Asn Cys Thr Cys Gly Cys Ser Val Gly Leu Glu Pro 
        435                 440                 445             


Asn Ser Ala Arg Cys Asn Gly Ser Gly Thr Tyr Val Cys Gly Leu Cys 
    450                 455                 460                 


Glu Cys Ser Pro Gly Tyr Leu Gly Thr Arg Cys Glu Cys Gln Asp Gly 
465                 470                 475                 480 


Glu Asn Gln Ser Val Tyr Gln Asn Leu Cys Arg Glu Ala Glu Gly Lys 
                485                 490                 495     


Pro Leu Cys Ser Gly Arg Gly Asp Cys Ser Cys Asn Gln Cys Ser Cys 
            500                 505                 510         


Phe Glu Ser Glu Phe Gly Lys Ile Tyr Gly Pro Phe Cys Glu Cys Asp 
        515                 520                 525             


Asn Phe Ser Cys Ala Arg Asn Lys Gly Val Leu Cys Ser Gly His Gly 
    530                 535                 540                 


Glu Cys His Cys Gly Glu Cys Lys Cys His Ala Gly Tyr Ile Gly Asp 
545                 550                 555                 560 


Asn Cys Asn Cys Ser Thr Asp Ile Ser Thr Cys Arg Gly Arg Asp Gly 
                565                 570                 575     


Gln Ile Cys Ser Glu Arg Gly His Cys Leu Cys Gly Gln Cys Gln Cys 
            580                 585                 590         


Thr Glu Pro Gly Ala Phe Gly Glu Met Cys Glu Lys Cys Pro Thr Cys 
        595                 600                 605             


Pro Asp Ala Cys Ser Thr Lys Arg Asp Cys Val Glu Cys Leu Leu Leu 
    610                 615                 620                 


His Ser Gly Lys Pro Asp Asn Gln Thr Cys His Ser Leu Cys Arg Asp 
625                 630                 635                 640 


Glu Val Ile Thr Trp Val Asp Thr Ile Val Lys Asp Asp Gln Glu Ala 
                645                 650                 655     


Val Leu Cys Phe Tyr Lys Thr Ala Lys Asp Cys Val Met Met Phe Thr 
            660                 665                 670         


Tyr Val Glu Leu Pro Ser Gly Lys Ser Asn Leu Thr Val Leu Arg Glu 
        675                 680                 685             


Pro Glu Cys Gly Asn Thr Pro Asn 
    690                 695     


<210>  742
<211>  688
<212>  PRT
<213>  Homo Sapiens

<400>  742

Gly Cys Ala Leu Gly Gly Ala Glu Thr Cys Glu Asp Cys Leu Leu Ile 
1               5                   10                  15      


Gly Pro Gln Cys Ala Trp Cys Ala Gln Glu Asn Phe Thr His Pro Ser 
            20                  25                  30          


Gly Val Gly Glu Arg Cys Asp Thr Pro Ala Asn Leu Leu Ala Lys Gly 
        35                  40                  45              


Cys Gln Leu Asn Phe Ile Glu Asn Pro Val Ser Gln Val Glu Ile Leu 
    50                  55                  60                  


Lys Asn Lys Pro Leu Ser Val Gly Arg Gln Lys Asn Ser Ser Asp Ile 
65                  70                  75                  80  


Val Gln Ile Ala Pro Gln Ser Leu Ile Leu Lys Leu Arg Pro Gly Gly 
                85                  90                  95      


Ala Gln Thr Leu Gln Val His Val Arg Gln Thr Glu Asp Tyr Pro Val 
            100                 105                 110         


Asp Leu Tyr Tyr Leu Met Asp Leu Ser Ala Ser Met Asp Asp Asp Leu 
        115                 120                 125             


Asn Thr Ile Lys Glu Leu Gly Ser Arg Leu Ser Lys Glu Met Ser Lys 
    130                 135                 140                 


Leu Thr Ser Asn Phe Arg Leu Gly Phe Gly Ser Phe Val Glu Lys Pro 
145                 150                 155                 160 


Val Ser Pro Phe Val Lys Thr Thr Pro Glu Glu Ile Ala Asn Pro Cys 
                165                 170                 175     


Ser Ser Ile Pro Tyr Phe Cys Leu Pro Thr Phe Gly Phe Lys His Ile 
            180                 185                 190         


Leu Pro Leu Thr Asn Asp Ala Glu Arg Phe Asn Glu Ile Val Lys Asn 
        195                 200                 205             


Gln Lys Ile Ser Ala Asn Ile Asp Thr Pro Glu Gly Gly Phe Asp Ala 
    210                 215                 220                 


Ile Met Gln Ala Ala Val Cys Lys Glu Lys Ile Gly Trp Arg Asn Asp 
225                 230                 235                 240 


Ser Leu His Leu Leu Val Phe Val Ser Asp Ala Asp Ser His Phe Gly 
                245                 250                 255     


Met Asp Ser Lys Leu Ala Gly Ile Val Ile Pro Asn Asp Gly Leu Cys 
            260                 265                 270         


His Leu Asp Ser Lys Asn Glu Tyr Ser Met Ser Thr Val Leu Glu Tyr 
        275                 280                 285             


Pro Thr Ile Gly Gln Leu Ile Asp Lys Leu Val Gln Asn Asn Val Leu 
    290                 295                 300                 


Leu Ile Phe Ala Val Thr Gln Glu Gln Val His Leu Tyr Glu Asn Tyr 
305                 310                 315                 320 


Ala Lys Leu Ile Pro Gly Ala Thr Val Gly Leu Leu Gln Lys Asp Ser 
                325                 330                 335     


Gly Asn Ile Leu Gln Leu Ile Ile Ser Ala Tyr Glu Glu Leu Arg Ser 
            340                 345                 350         


Glu Val Glu Leu Glu Val Leu Gly Asp Thr Glu Gly Leu Asn Leu Ser 
        355                 360                 365             


Phe Thr Ala Ile Cys Asn Asn Gly Thr Leu Phe Gln His Gln Lys Lys 
    370                 375                 380                 


Cys Ser His Met Lys Val Gly Asp Thr Ala Ser Phe Ser Val Thr Val 
385                 390                 395                 400 


Asn Ile Pro His Cys Glu Arg Arg Ser Arg His Ile Ile Ile Lys Pro 
                405                 410                 415     


Val Gly Leu Gly Asp Ala Leu Glu Leu Leu Val Ser Pro Glu Cys Asn 
            420                 425                 430         


Cys Asp Cys Gln Lys Glu Val Glu Val Asn Ser Pro Lys Cys His His 
        435                 440                 445             


Gly Asn Gly Ser Phe Gln Cys Gly Ala Cys Ala Cys His Pro Gly His 
    450                 455                 460                 


Met Gly Pro Arg Cys Glu Cys Gly Glu Asp Met Leu Ser Thr Asp Ser 
465                 470                 475                 480 


Cys Lys Glu Ala Pro Asp His Pro Ser Cys Ser Gly Arg Gly Asp Cys 
                485                 490                 495     


Tyr Cys Gly Gln Cys Ile Cys His Leu Ser Pro Tyr Gly Asn Ile Tyr 
            500                 505                 510         


Gly Pro Tyr Cys Gln Cys Asp Asn Phe Ser Cys Val Arg His Lys Gly 
        515                 520                 525             


Leu Leu Cys Gly Gly Asn Gly Asp Cys Asp Cys Gly Glu Cys Val Cys 
    530                 535                 540                 


Arg Ser Gly Trp Thr Gly Glu Tyr Cys Asn Cys Thr Thr Ser Thr Asp 
545                 550                 555                 560 


Ser Cys Val Ser Glu Asp Gly Val Leu Cys Ser Gly Arg Gly Asp Cys 
                565                 570                 575     


Val Cys Gly Lys Cys Val Cys Thr Asn Pro Gly Ala Ser Gly Pro Thr 
            580                 585                 590         


Cys Glu Arg Cys Pro Thr Cys Gly Asp Pro Cys Asn Ser Lys Arg Ser 
        595                 600                 605             


Cys Ile Glu Cys His Leu Ser Ala Ala Gly Gln Ala Arg Glu Glu Cys 
    610                 615                 620                 


Val Asp Lys Cys Lys Leu Ala Gly Ala Thr Ile Ser Glu Glu Glu Asp 
625                 630                 635                 640 


Phe Ser Lys Asp Gly Ser Val Ser Cys Ser Leu Gln Gly Glu Asn Glu 
                645                 650                 655     


Cys Leu Ile Thr Phe Leu Ile Thr Thr Asp Asn Glu Gly Lys Thr Ile 
            660                 665                 670         


Ile His Ser Ile Asn Glu Lys Asp Cys Pro Lys Pro Pro Asn Ile Pro 
        675                 680                 685             


<210>  743
<211>  704
<212>  PRT
<213>  Homo Sapiens

<400>  743

Glu Leu Asp Ala Lys Ile Pro Ser Thr Gly Asp Ala Thr Glu Trp Arg 
1               5                   10                  15      


Asn Pro His Leu Ser Met Leu Gly Ser Cys Gln Pro Ala Pro Ser Cys 
            20                  25                  30          


Gln Lys Cys Ile Leu Ser His Pro Ser Cys Ala Trp Cys Lys Gln Leu 
        35                  40                  45              


Asn Phe Thr Ala Ser Gly Glu Ala Glu Ala Arg Arg Cys Ala Arg Arg 
    50                  55                  60                  


Glu Glu Leu Leu Ala Arg Gly Cys Pro Leu Glu Glu Leu Glu Glu Pro 
65                  70                  75                  80  


Arg Gly Gln Gln Glu Val Leu Gln Asp Gln Pro Leu Ser Gln Gly Ala 
                85                  90                  95      


Arg Gly Glu Gly Ala Thr Gln Leu Ala Pro Gln Arg Val Arg Val Thr 
            100                 105                 110         


Leu Arg Pro Gly Glu Pro Gln Gln Leu Gln Val Arg Phe Leu Arg Ala 
        115                 120                 125             


Glu Gly Tyr Pro Val Asp Leu Tyr Tyr Leu Met Asp Leu Ser Tyr Ser 
    130                 135                 140                 


Met Lys Asp Asp Leu Glu Arg Val Arg Gln Leu Gly His Ala Leu Leu 
145                 150                 155                 160 


Val Arg Leu Gln Glu Val Thr His Ser Val Arg Ile Gly Phe Gly Ser 
                165                 170                 175     


Phe Val Asp Lys Thr Val Leu Pro Phe Val Ser Thr Val Pro Ser Lys 
            180                 185                 190         


Leu Arg His Pro Cys Pro Thr Arg Leu Glu Arg Cys Gln Ser Pro Phe 
        195                 200                 205             


Ser Phe His His Val Leu Ser Leu Thr Gly Asp Ala Gln Ala Phe Glu 
    210                 215                 220                 


Arg Glu Val Gly Arg Gln Ser Val Ser Gly Asn Leu Asp Ser Pro Glu 
225                 230                 235                 240 


Gly Gly Phe Asp Ala Ile Leu Gln Ala Ala Leu Cys Gln Glu Gln Ile 
                245                 250                 255     


Gly Trp Arg Asn Val Ser Arg Leu Leu Val Phe Thr Ser Asp Asp Thr 
            260                 265                 270         


Phe His Thr Ala Gly Asp Gly Lys Leu Gly Gly Ile Phe Met Pro Ser 
        275                 280                 285             


Asp Gly His Cys His Leu Asp Ser Asn Gly Leu Tyr Ser Arg Ser Thr 
    290                 295                 300                 


Glu Phe Asp Tyr Pro Ser Val Gly Gln Val Ala Gln Ala Leu Ser Ala 
305                 310                 315                 320 


Ala Asn Ile Gln Pro Ile Phe Ala Val Thr Ser Ala Ala Leu Pro Val 
                325                 330                 335     


Tyr Gln Glu Leu Ser Lys Leu Ile Pro Lys Ser Ala Val Gly Glu Leu 
            340                 345                 350         


Ser Glu Asp Ser Ser Asn Val Val Gln Leu Ile Met Asp Ala Tyr Asn 
        355                 360                 365             


Ser Leu Ser Ser Thr Val Thr Leu Glu His Ser Ser Leu Pro Pro Gly 
    370                 375                 380                 


Val His Ile Ser Tyr Glu Ser Gln Cys Glu Gly Pro Glu Lys Arg Glu 
385                 390                 395                 400 


Gly Lys Ala Glu Asp Arg Gly Gln Cys Asn His Val Arg Ile Asn Gln 
                405                 410                 415     


Thr Val Thr Phe Trp Val Ser Leu Gln Ala Thr His Cys Leu Pro Glu 
            420                 425                 430         


Pro His Leu Leu Arg Leu Arg Ala Leu Gly Phe Ser Glu Glu Leu Ile 
        435                 440                 445             


Val Glu Leu His Thr Leu Cys Asp Cys Asn Cys Ser Asp Thr Gln Pro 
    450                 455                 460                 


Gln Ala Pro His Cys Ser Asp Gly Gln Gly His Leu Gln Cys Gly Val 
465                 470                 475                 480 


Cys Ser Cys Ala Pro Gly Arg Leu Gly Arg Leu Cys Glu Cys Ser Val 
                485                 490                 495     


Ala Glu Leu Ser Ser Pro Asp Leu Glu Ser Gly Cys Arg Ala Pro Asn 
            500                 505                 510         


Gly Thr Gly Pro Leu Cys Ser Gly Lys Gly His Cys Gln Cys Gly Arg 
        515                 520                 525             


Cys Ser Cys Ser Gly Gln Ser Ser Gly His Leu Cys Glu Cys Asp Asp 
    530                 535                 540                 


Ala Ser Cys Glu Arg His Glu Gly Ile Leu Cys Gly Gly Phe Gly Arg 
545                 550                 555                 560 


Cys Gln Cys Gly Val Cys His Cys His Ala Asn Arg Thr Gly Arg Ala 
                565                 570                 575     


Cys Glu Cys Ser Gly Asp Met Asp Ser Cys Ile Ser Pro Glu Gly Gly 
            580                 585                 590         


Leu Cys Ser Gly His Gly Arg Cys Lys Cys Asn Arg Cys Gln Cys Leu 
        595                 600                 605             


Asp Gly Tyr Tyr Gly Ala Leu Cys Asp Gln Cys Pro Gly Cys Lys Thr 
    610                 615                 620                 


Pro Cys Glu Arg His Arg Asp Cys Ala Glu Cys Gly Ala Phe Arg Thr 
625                 630                 635                 640 


Gly Pro Leu Ala Thr Asn Cys Ser Thr Ala Cys Ala His Thr Asn Val 
                645                 650                 655     


Thr Leu Ala Leu Ala Pro Ile Leu Asp Asp Gly Trp Cys Lys Glu Arg 
            660                 665                 670         


Thr Leu Asp Asn Gln Leu Phe Phe Phe Leu Val Glu Asp Asp Ala Arg 
        675                 680                 685             


Gly Thr Val Val Leu Arg Val Arg Pro Gln Glu Lys Gly Ala Asp His 
    690                 695                 700                 


<210>  744
<211>  397
<212>  PRT
<213>  Homo Sapiens

<400>  744

Glu Asp Asn Arg Cys Ala Ser Ser Asn Ala Ala Ser Cys Ala Arg Cys 
1               5                   10                  15      


Leu Ala Leu Gly Pro Glu Cys Gly Trp Cys Val Gln Glu Asp Phe Ile 
            20                  25                  30          


Ser Gly Gly Ser Arg Ser Glu Arg Cys Asp Ile Val Ser Asn Leu Ile 
        35                  40                  45              


Ser Lys Gly Cys Ser Val Asp Ser Ile Glu Tyr Pro Ser Val His Val 
    50                  55                  60                  


Ile Ile Pro Thr Glu Asn Glu Ile Asn Thr Gln Val Thr Pro Gly Glu 
65                  70                  75                  80  


Val Ser Ile Gln Leu Arg Pro Gly Ala Glu Ala Asn Phe Met Leu Lys 
                85                  90                  95      


Val His Pro Leu Lys Lys Tyr Pro Val Asp Leu Tyr Tyr Leu Val Asp 
            100                 105                 110         


Val Ser Ala Ser Met His Asn Asn Ile Glu Lys Leu Asn Ser Val Gly 
        115                 120                 125             


Asn Asp Leu Ser Arg Lys Met Ala Phe Phe Ser Arg Asp Phe Arg Leu 
    130                 135                 140                 


Gly Phe Gly Ser Tyr Val Asp Lys Thr Val Ser Pro Tyr Ile Ser Ile 
145                 150                 155                 160 


His Pro Glu Arg Ile His Asn Gln Cys Ser Asp Tyr Asn Leu Asp Cys 
                165                 170                 175     


Met Pro Pro His Gly Tyr Ile His Val Leu Ser Leu Thr Glu Asn Ile 
            180                 185                 190         


Thr Glu Phe Glu Lys Ala Val His Arg Gln Lys Ile Ser Gly Asn Ile 
        195                 200                 205             


Asp Thr Pro Glu Gly Gly Phe Asp Ala Met Leu Gln Ala Ala Val Cys 
    210                 215                 220                 


Glu Ser His Ile Gly Trp Arg Lys Glu Ala Lys Arg Leu Leu Leu Val 
225                 230                 235                 240 


Met Thr Asp Gln Thr Ser His Leu Ala Leu Asp Ser Lys Leu Ala Gly 
                245                 250                 255     


Ile Val Val Pro Asn Asp Gly Asn Cys His Leu Lys Asn Asn Val Tyr 
            260                 265                 270         


Val Lys Ser Thr Thr Met Glu His Pro Ser Leu Gly Gln Leu Ser Glu 
        275                 280                 285             


Lys Leu Ile Asp Asn Asn Ile Asn Val Ile Phe Ala Val Gln Gly Lys 
    290                 295                 300                 


Gln Phe His Trp Tyr Lys Asp Leu Leu Pro Leu Leu Pro Gly Thr Ile 
305                 310                 315                 320 


Ala Gly Glu Ile Glu Ser Lys Ala Ala Asn Leu Asn Asn Leu Val Val 
                325                 330                 335     


Glu Ala Tyr Gln Lys Leu Ile Ser Glu Val Lys Val Gln Val Glu Asn 
            340                 345                 350         


Gln Val Gln Gly Ile Tyr Phe Asn Ile Thr Ala Ile Cys Pro Asp Gly 
        355                 360                 365             


Ser Arg Lys Pro Gly Met Glu Gly Cys Arg Asn Val Thr Ser Asn Asp 
    370                 375                 380                 


Glu Val Cys Gly Cys Ala Phe Phe Pro Phe Lys Ile Asn 
385                 390                 395         


<210>  745
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  745

Val Pro Gln Ser Phe Ser Pro Ser Leu Arg Ser Trp Pro Gly Ala Ala 
1               5                   10                  15      


Cys Arg Leu Ser Arg Ala Glu Ser Glu Arg Arg Cys Arg Ala Pro Gly 
            20                  25                  30          


Gln Pro Pro Gly Ala Ala Leu Cys His Gly Arg Gly Arg Cys Asp Cys 
        35                  40                  45              


Gly Val Cys Ile Cys His Val Thr Glu Pro Gly Met Phe Phe Gly Pro 
    50                  55                  60                  


Leu Cys Glu Cys His Glu Trp Val Cys Glu Thr Tyr Asp Gly Ser Thr 
65                  70                  75                  80  


Cys Ala Gly His Gly Lys Cys Asp Cys Gly Lys Cys Lys Cys Asp Gln 
                85                  90                  95      


Gly Trp Tyr Gly Asp Ala Cys Gln Tyr Pro Thr Asn Cys Asp Leu Thr 
            100                 105                 110         


Lys Lys Lys Ser Asn Gln Met Cys Lys Asn Ser Gln Asp Ile Ile Cys 
        115                 120                 125             


Ser Asn Ala Gly Thr Cys His Cys Gly Arg Cys Lys Cys Asp Asn Ser 
    130                 135                 140                 


Asp Gly Ser Gly Leu Val Tyr Gly Lys Phe Cys Glu Cys Asp Asp Arg 
145                 150                 155                 160 


Glu Cys Ile Asp Asp Glu Thr Glu Glu Ile Cys Gly Gly His Gly Lys 
                165                 170                 175     


Cys Tyr Cys Gly Asn Cys Tyr Cys Lys Ala Gly Trp His Gly Asp Lys 
            180                 185                 190         


Cys Glu Phe Gln Cys Asp Ile Thr Pro Trp Glu Ser Lys Arg Arg Cys 
        195                 200                 205             


Thr Ser Pro Asp Gly Lys Ile Cys Ser Asn Arg Gly Thr Cys Val Cys 
    210                 215                 220                 


Gly Glu Cys Thr Cys His Asp Val Asp Pro Thr Gly Asp Trp Gly Asp 
225                 230                 235                 240 


Ile His Gly Asp Thr Cys Glu Cys Asp Glu Arg Asp Cys Arg Ala Val 
                245                 250                 255     


Tyr Asp Arg Tyr Ser Asp Asp Phe Cys Ser Gly His Gly Gln Cys Asn 
            260                 265                 270         


Cys Gly Arg Cys Asp Cys Lys Ala Gly Trp Tyr Gly Lys Lys Cys Glu 
        275                 280                 285             


His Pro Gln Ser Cys Thr Leu Ser Ala Glu Glu Ser Ile Arg Lys Cys 
    290                 295                 300                 


Gln Gly Ser Ser Asp Leu Pro Cys Ser Gly Arg Gly Lys Cys Glu Cys 
305                 310                 315                 320 


Gly Lys Cys Thr Cys Tyr Pro Pro Gly Asp Arg Arg Val Tyr Gly Lys 
                325                 330                 335     


Thr Cys Glu Cys Asp Asp Arg Arg Cys Glu Asp Leu Asp Gly Val Val 
            340                 345                 350         


Cys Gly Gly His Gly Thr Cys Ser Cys Gly Arg Cys Val Cys Glu Arg 
        355                 360                 365             


Gly Trp Phe Gly Lys Leu Cys Gln His Pro Arg Lys Cys Asn Met Thr 
    370                 375                 380                 


Glu Glu Gln Ser Lys Asn Leu Cys Glu Ser Ala Asp Gly Ile Leu Cys 
385                 390                 395                 400 


Ser Gly Lys Gly Ser Cys His Cys Gly Lys Cys Ile Cys Ser Ala Glu 
                405                 410                 415     


Glu Trp Tyr Ile Ser Gly Glu Phe Cys Asp Cys Asp Asp Arg Asp Cys 
            420                 425                 430         


Asp Lys His Asp Gly Leu Ile Cys Thr Gly Asn Gly Ile Cys Ser Cys 
        435                 440                 445             


Gly Asn Cys Glu Cys Trp Asp Gly Trp Asn Gly Asn Ala Cys Glu Ile 
    450                 455                 460                 


Trp Leu Gly Ser Glu Tyr Pro 
465                 470     


<210>  746
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  746

Cys Val Ile Cys Asp Pro Ser Val Val Leu Ala Leu Lys Ser Leu Glu 
1               5                   10                  15      


Lys Asp Tyr Leu Pro Gly His Leu Asp Ala Lys His His Lys Ala Met 
            20                  25                  30          


Met Glu Arg Val Glu Asn Ala Val Lys Asp Phe Gln Glu Leu Ser Leu 
        35                  40                  45              


Asn Glu Asp Ala Tyr Met Gly Val Val Asp Glu Ala Thr Leu Gln Lys 
    50                  55                  60                  


Gly Ser Trp Ser Leu Leu Lys Asp Leu Lys Arg Ile Thr Asp Ser Asp 
65                  70                  75                  80  


Val Lys Gly Asp Leu Phe Val Lys Glu Leu Phe Trp Met Leu His Leu 
                85                  90                  95      


Gln Lys Glu Thr Phe Ala Thr Tyr Val Ala Arg Phe Gln Lys Glu Ala 
            100                 105                 110         


Tyr Cys Pro Asn Lys Cys Gly Val Met Leu Gln Thr Leu Ile Trp Cys 
        115                 120                 125             


Lys Asn Cys Lys Lys Glu Val His Ala Cys Arg Lys Ser Tyr Asp Cys 
    130                 135                 140                 


Gly Glu Arg Asn Val Glu Val Pro Gln Met Glu Asp Met Ile Leu Asp 
145                 150                 155                 160 


Cys Glu Leu Asn Trp His Gln Ala Ser Glu Gly Leu Thr Asp Tyr Ser 
                165                 170                 175     


Phe Tyr Arg Val Trp Gly Asn Asn Thr Glu Thr Leu Val Ser Lys Gly 
            180                 185                 190         


Lys Glu Ala Thr Leu Thr Lys Pro Met Val Gly Pro Glu Asp Ala Gly 
        195                 200                 205             


Ser Tyr Arg Cys Glu Leu Gly Ser Val Asn Ser Ser Pro Ala Thr Ile 
    210                 215                 220                 


Ile Asn Phe His Val Thr Val Leu Pro Lys Met Ile Lys Glu Glu Lys 
225                 230                 235                 240 


Pro Ser Pro Asn Ile Val Thr Pro Gly Glu Ala Thr Thr Glu Ser Ser 
                245                 250                 255     


Ile Ser Leu Gln Pro Leu Gln Pro Glu Lys Met Leu Ala Ser Arg 
            260                 265                 270     


<210>  747
<211>  1034
<212>  PRT
<213>  Homo Sapiens

<400>  747

Gln Phe Glu Leu Glu Ile Leu Ser Met Gln Asn Val Asn Gly Glu Leu 
1               5                   10                  15      


Gln Asn Gly Asn Cys Cys Gly Gly Ala Arg Asn Pro Gly Asp Arg Lys 
            20                  25                  30          


Cys Thr Arg Asp Glu Cys Asp Thr Tyr Phe Lys Val Cys Leu Lys Glu 
        35                  40                  45              


Tyr Gln Ser Arg Val Thr Ala Gly Gly Pro Cys Ser Phe Gly Ser Gly 
    50                  55                  60                  


Ser Thr Pro Val Ile Gly Gly Asn Thr Phe Asn Leu Lys Ala Ser Arg 
65                  70                  75                  80  


Gly Asn Asp Arg Asn Arg Ile Val Leu Pro Phe Ser Phe Ala Trp Pro 
                85                  90                  95      


Arg Ser Tyr Thr Leu Leu Val Glu Ala Trp Asp Ser Ser Asn Asp Thr 
            100                 105                 110         


Val Gln Pro Asp Ser Ile Ile Glu Lys Ala Ser His Ser Gly Met Ile 
        115                 120                 125             


Asn Pro Ser Arg Gln Trp Gln Thr Leu Lys Gln Asn Thr Gly Val Ala 
    130                 135                 140                 


His Phe Glu Tyr Gln Ile Arg Val Thr Cys Asp Asp Tyr Tyr Tyr Gly 
145                 150                 155                 160 


Phe Gly Cys Asn Lys Phe Cys Arg Pro Arg Asp Asp Phe Phe Gly His 
                165                 170                 175     


Tyr Ala Cys Asp Gln Asn Gly Asn Lys Thr Cys Met Glu Gly Trp Met 
            180                 185                 190         


Gly Pro Glu Cys Asn Arg Ala Ile Cys Arg Gln Gly Cys Ser Pro Lys 
        195                 200                 205             


His Gly Ser Cys Lys Leu Pro Gly Asp Cys Arg Cys Gln Tyr Gly Trp 
    210                 215                 220                 


Gln Gly Leu Tyr Cys Asp Lys Cys Ile Pro His Pro Gly Cys Val His 
225                 230                 235                 240 


Gly Ile Cys Asn Glu Pro Trp Gln Cys Leu Cys Glu Thr Asn Trp Gly 
                245                 250                 255     


Gly Gln Leu Cys Asp Lys Asp Leu Asn Tyr Cys Gly Thr His Gln Pro 
            260                 265                 270         


Cys Leu Asn Gly Gly Thr Cys Ser Asn Thr Gly Pro Asp Lys Tyr Gln 
        275                 280                 285             


Cys Ser Cys Pro Glu Gly Tyr Ser Gly Pro Asn Cys Glu Ile Ala Glu 
    290                 295                 300                 


His Ala Cys Leu Ser Asp Pro Cys His Asn Arg Gly Ser Cys Lys Glu 
305                 310                 315                 320 


Thr Ser Leu Gly Phe Glu Cys Glu Cys Ser Pro Gly Trp Thr Gly Pro 
                325                 330                 335     


Thr Cys Ser Thr Asn Ile Asp Asp Cys Ser Pro Asn Asn Cys Ser His 
            340                 345                 350         


Gly Gly Thr Cys Gln Asp Leu Val Asn Gly Phe Lys Cys Val Cys Pro 
        355                 360                 365             


Pro Gln Trp Thr Gly Lys Thr Cys Gln Leu Asp Ala Asn Glu Cys Glu 
    370                 375                 380                 


Ala Lys Pro Cys Val Asn Ala Lys Ser Cys Lys Asn Leu Ile Ala Ser 
385                 390                 395                 400 


Tyr Tyr Cys Asp Cys Leu Pro Gly Trp Met Gly Gln Asn Cys Asp Ile 
                405                 410                 415     


Asn Ile Asn Asp Cys Leu Gly Gln Cys Gln Asn Asp Ala Ser Cys Arg 
            420                 425                 430         


Asp Leu Val Asn Gly Tyr Arg Cys Ile Cys Pro Pro Gly Tyr Ala Gly 
        435                 440                 445             


Asp His Cys Glu Arg Asp Ile Asp Glu Cys Ala Ser Asn Pro Cys Leu 
    450                 455                 460                 


Asn Gly Gly His Cys Gln Asn Glu Ile Asn Arg Phe Gln Cys Leu Cys 
465                 470                 475                 480 


Pro Thr Gly Phe Ser Gly Asn Leu Cys Gln Leu Asp Ile Asp Tyr Cys 
                485                 490                 495     


Glu Pro Asn Pro Cys Gln Asn Gly Ala Gln Cys Tyr Asn Arg Ala Ser 
            500                 505                 510         


Asp Tyr Phe Cys Lys Cys Pro Glu Asp Tyr Glu Gly Lys Asn Cys Ser 
        515                 520                 525             


His Leu Lys Asp His Cys Arg Thr Thr Pro Cys Glu Val Ile Asp Ser 
    530                 535                 540                 


Cys Thr Val Ala Met Ala Ser Asn Asp Thr Pro Glu Gly Val Arg Tyr 
545                 550                 555                 560 


Ile Ser Ser Asn Val Cys Gly Pro His Gly Lys Cys Lys Ser Gln Ser 
                565                 570                 575     


Gly Gly Lys Phe Thr Cys Asp Cys Asn Lys Gly Phe Thr Gly Thr Tyr 
            580                 585                 590         


Cys His Glu Asn Ile Asn Asp Cys Glu Ser Asn Pro Cys Arg Asn Gly 
        595                 600                 605             


Gly Thr Cys Ile Asp Gly Val Asn Ser Tyr Lys Cys Ile Cys Ser Asp 
    610                 615                 620                 


Gly Trp Glu Gly Ala Tyr Cys Glu Thr Asn Ile Asn Asp Cys Ser Gln 
625                 630                 635                 640 


Asn Pro Cys His Asn Gly Gly Thr Cys Arg Asp Leu Val Asn Asp Phe 
                645                 650                 655     


Tyr Cys Asp Cys Lys Asn Gly Trp Lys Gly Lys Thr Cys His Ser Arg 
            660                 665                 670         


Asp Ser Gln Cys Asp Glu Ala Thr Cys Asn Asn Gly Gly Thr Cys Tyr 
        675                 680                 685             


Asp Glu Gly Asp Ala Phe Lys Cys Met Cys Pro Gly Gly Trp Glu Gly 
    690                 695                 700                 


Thr Thr Cys Asn Ile Ala Arg Asn Ser Ser Cys Leu Pro Asn Pro Cys 
705                 710                 715                 720 


His Asn Gly Gly Thr Cys Val Val Asn Gly Glu Ser Phe Thr Cys Val 
                725                 730                 735     


Cys Lys Glu Gly Trp Glu Gly Pro Ile Cys Ala Gln Asn Thr Asn Asp 
            740                 745                 750         


Cys Ser Pro His Pro Cys Tyr Asn Ser Gly Thr Cys Val Asp Gly Asp 
        755                 760                 765             


Asn Trp Tyr Arg Cys Glu Cys Ala Pro Gly Phe Ala Gly Pro Asp Cys 
    770                 775                 780                 


Arg Ile Asn Ile Asn Glu Cys Gln Ser Ser Pro Cys Ala Phe Gly Ala 
785                 790                 795                 800 


Thr Cys Val Asp Glu Ile Asn Gly Tyr Arg Cys Val Cys Pro Pro Gly 
                805                 810                 815     


His Ser Gly Ala Lys Cys Gln Glu Val Ser Gly Arg Pro Cys Ile Thr 
            820                 825                 830         


Met Gly Ser Val Ile Pro Asp Gly Ala Lys Trp Asp Asp Asp Cys Asn 
        835                 840                 845             


Thr Cys Gln Cys Leu Asn Gly Arg Ile Ala Cys Ser Lys Val Trp Cys 
    850                 855                 860                 


Gly Pro Arg Pro Cys Leu Leu His Lys Gly His Ser Glu Cys Pro Ser 
865                 870                 875                 880 


Gly Gln Ser Cys Ile Pro Ile Leu Asp Asp Gln Cys Phe Val His Pro 
                885                 890                 895     


Cys Thr Gly Val Gly Glu Cys Arg Ser Ser Ser Leu Gln Pro Val Lys 
            900                 905                 910         


Thr Lys Cys Thr Ser Asp Ser Tyr Tyr Gln Asp Asn Cys Ala Asn Ile 
        915                 920                 925             


Thr Phe Thr Phe Asn Lys Glu Met Met Ser Pro Gly Leu Thr Thr Glu 
    930                 935                 940                 


His Ile Cys Ser Glu Leu Arg Asn Leu Asn Ile Leu Lys Asn Val Ser 
945                 950                 955                 960 


Ala Glu Tyr Ser Ile Tyr Ile Ala Cys Glu Pro Ser Pro Ser Ala Asn 
                965                 970                 975     


Asn Glu Ile His Val Ala Ile Ser Ala Glu Asp Ile Arg Asp Asp Gly 
            980                 985                 990         


Asn Pro Ile Lys Glu Ile Thr Asp  Lys Ile Ile Asp Leu  Val Ser Lys 
        995                 1000                 1005             


Arg Asp  Gly Asn Ser Ser Leu  Ile Ala Ala Val Ala  Glu Val Arg 
    1010                 1015                 1020             


Val Gln  Arg Arg Pro Leu Lys  Asn Arg Thr Asp 
    1025                 1030                 


<210>  748
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  748

Met Gly Tyr Phe Glu Leu Gln Leu Ser Ala Leu Arg Asn Val Asn Gly 
1               5                   10                  15      


Glu Leu Leu Ser Gly Ala Cys Cys Asp Gly Asp Gly Arg Thr Thr Arg 
            20                  25                  30          


Ala Gly Gly Cys Gly His Asp Glu Cys Asp Thr Tyr Val Arg Val Cys 
        35                  40                  45              


Leu Lys Glu Tyr Gln Ala Lys Val Thr Pro Thr Gly Pro Cys Ser Tyr 
    50                  55                  60                  


Gly His Gly Ala Thr Pro Val Leu Gly Gly Asn Ser Phe Tyr Leu Pro 
65                  70                  75                  80  


Pro Ala Gly Ala Ala Gly Asp Arg Ala Arg Ala Arg Ala Arg Ala Gly 
                85                  90                  95      


Gly Asp Gln Asp Pro Gly Leu Val Val Ile Pro Phe Gln Phe Ala Trp 
            100                 105                 110         


Pro Arg Ser Phe Thr Leu Ile Val Glu Ala Trp Asp Trp Asp Asn Asp 
        115                 120                 125             


Thr Thr Pro Asn Glu Glu Leu Leu Ile Glu Arg Val Ser His Ala Gly 
    130                 135                 140                 


Met Ile Asn Pro Glu Asp Arg Trp Lys Ser Leu His Phe Ser Gly His 
145                 150                 155                 160 


Val Ala His Leu Glu Leu Gln Ile Arg Val Arg Cys Asp Glu Asn Tyr 
                165                 170                 175     


Tyr Ser Ala Thr Cys Asn Lys Phe Cys Arg Pro Arg Asn Asp Phe Phe 
            180                 185                 190         


Gly His Tyr Thr Cys Asp Gln Tyr Gly Asn Lys Ala Cys Met Asp Gly 
        195                 200                 205             


Trp Met Gly Lys Glu Cys Lys Glu Ala Val Cys Lys Gln Gly Cys Asn 
    210                 215                 220                 


Leu Leu His Gly Gly Cys Thr Val Pro Gly Glu Cys Arg Cys Ser Tyr 
225                 230                 235                 240 


Gly Trp Gln Gly Arg Phe Cys Asp Glu Cys Val Pro Tyr Pro Gly Cys 
                245                 250                 255     


Val His Gly Ser Cys Val Glu Pro Trp Gln Cys Asn Cys Glu Thr Asn 
            260                 265                 270         


Trp Gly Gly Leu Leu Cys Asp Lys Asp Leu Asn Tyr Cys Gly Ser His 
        275                 280                 285             


His Pro Cys Thr Asn Gly Gly Thr Cys Ile Asn Ala Glu Pro Asp Gln 
    290                 295                 300                 


Tyr Arg Cys Thr Cys Pro Asp Gly Tyr Ser Gly Arg Asn Cys Glu 
305                 310                 315                 


<210>  749
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  749

Phe Ser Ala Pro Lys Asp Gln Gln Val Val Thr Ala Val Glu Tyr Gln 
1               5                   10                  15      


Glu Ala Ile Leu Ala Cys Lys Thr Pro Lys Lys Thr Val Ser Ser Arg 
            20                  25                  30          


Leu Glu Trp Lys Lys Leu Gly Arg Ser Val Ser Phe Val Tyr Tyr Gln 
        35                  40                  45              


Gln Thr Leu Gln Gly Asp Phe Lys Asn Arg Ala Glu Met Ile Asp Phe 
    50                  55                  60                  


Asn Ile Arg Ile Lys Asn Val Thr Arg Ser Asp Ala Gly Lys Tyr Arg 
65                  70                  75                  80  


Cys Glu Val Ser Ala Pro Ser Glu Gln Gly Gln Asn Leu Glu Glu Asp 
                85                  90                  95      


Thr Val Thr Leu Glu Val Leu Val Ala Pro Ala Val Pro Ser Cys Glu 
            100                 105                 110         


Val Pro Ser Ser Ala Leu Ser Gly Thr Val Val Glu Leu Arg Cys Gln 
        115                 120                 125             


Asp Lys Glu Gly Asn Pro Ala Pro Glu Tyr Thr Trp Phe Lys Asp Gly 
    130                 135                 140                 


Ile Arg Leu Leu Glu Asn Pro Arg Leu Gly Ser Gln Ser Thr Asn Ser 
145                 150                 155                 160 


Ser Tyr Thr Met Asn Thr Lys Thr Gly Thr Leu Gln Phe Asn Thr Val 
                165                 170                 175     


Ser Lys Leu Asp Thr Gly Glu Tyr Ser Cys Glu Ala Arg Asn Ser Val 
            180                 185                 190         


Gly Tyr Arg Arg Cys Pro Gly Lys Arg Met Gln Val Asp Asp Leu Asn 
        195                 200                 205             


Ile Ser 
    210 


<210>  750
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  750

Val Asn Leu Lys Ser Ser Asn Arg Thr Pro Val Val Gln Glu Phe Glu 
1               5                   10                  15      


Ser Val Glu Leu Ser Cys Ile Ile Thr Asp Ser Gln Thr Ser Asp Pro 
            20                  25                  30          


Arg Ile Glu Trp Lys Lys Ile Gln Asp Glu Gln Thr Thr Tyr Val Phe 
        35                  40                  45              


Phe Asp Asn Lys Ile Gln Gly Asp Leu Ala Gly Arg Ala Glu Ile Leu 
    50                  55                  60                  


Gly Lys Thr Ser Leu Lys Ile Trp Asn Val Thr Arg Arg Asp Ser Ala 
65                  70                  75                  80  


Leu Tyr Arg Cys Glu Val Val Ala Arg Asn Asp Arg Lys Glu Ile Asp 
                85                  90                  95      


Glu Ile Val Ile Glu Leu Thr Val Gln Val Lys Pro Val Thr Pro Val 
            100                 105                 110         


Cys Arg Val Pro Lys Ala Val Pro Val Gly Lys Met Ala Thr Leu His 
        115                 120                 125             


Cys Gln Glu Ser Glu Gly His Pro Arg Pro His Tyr Ser Trp Tyr Arg 
    130                 135                 140                 


Asn Asp Val Pro Leu Pro Thr Asp Ser Arg Ala Asn Pro Arg Phe Arg 
145                 150                 155                 160 


Asn Ser Ser Phe His Leu Asn Ser Glu Thr Gly Thr Leu Val Phe Thr 
                165                 170                 175     


Ala Val His Lys Asp Asp Ser Gly Gln Tyr Tyr Cys Ile Ala Ser Asn 
            180                 185                 190         


Asp Ala Gly Ser Ala Arg Cys Glu Glu Gln Glu Met Glu Val Tyr Asp 
        195                 200                 205             


Leu Asn 
    210 


<210>  751
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  751

Gln Glu Asp Glu Arg Ile Val Leu Val Asp Asn Lys Cys Lys Cys Ala 
1               5                   10                  15      


Arg Ile Thr Ser Arg Ile Ile Arg Ser Ser Glu Asp Pro Asn Glu Asp 
            20                  25                  30          


Ile Val Glu Arg Asn Ile Arg Ile Ile Val Pro Leu Asn Asn Arg Glu 
        35                  40                  45              


Asn Ile Ser Asp Pro Thr Ser Pro Leu Arg Thr Arg Phe Val Tyr His 
    50                  55                  60                  


Leu Ser Asp Leu Cys Lys Lys Cys Asp Pro Thr Glu Val Glu Leu Asp 
65                  70                  75                  80  


Asn Gln Ile Val Thr Ala Thr Gln Ser Asn Ile Cys Asp Glu Asp Ser 
                85                  90                  95      


Ala Thr Glu Thr Cys Tyr Thr Tyr Asp Arg Asn Lys Cys Tyr Thr Ala 
            100                 105                 110         


Val Val Pro Leu Val Tyr Gly Gly Glu Thr Lys Met Val Glu Thr Ala 
        115                 120                 125             


Leu Thr Pro Asp Ala Cys Tyr Pro Asp 
    130                 135         


<210>  752
<211>  656
<212>  PRT
<213>  Homo Sapiens

<400>  752

Ala Gly Pro Gly Ala Ala Ala Ala Arg Arg Leu Asp Glu Ser Leu Ser 
1               5                   10                  15      


Ala Gly Ser Val Gln Arg Ala Arg Cys Ala Ser Arg Cys Leu Ser Leu 
            20                  25                  30          


Gln Ile Thr Arg Ile Ser Ala Phe Phe Gln His Phe Gln Asn Asn Gly 
        35                  40                  45              


Ser Leu Val Trp Cys Gln Asn His Lys Gln Cys Ser Lys Cys Leu Glu 
    50                  55                  60                  


Pro Cys Lys Glu Ser Gly Asp Leu Arg Lys His Gln Cys Gln Ser Phe 
65                  70                  75                  80  


Cys Glu Pro Leu Phe Pro Lys Lys Ser Tyr Glu Cys Leu Thr Ser Cys 
                85                  90                  95      


Glu Phe Leu Lys Tyr Ile Leu Leu Val Lys Gln Gly Asp Cys Pro Ala 
            100                 105                 110         


Pro Glu Lys Ala Ser Gly Phe Ala Ala Ala Cys Val Glu Ser Cys Glu 
        115                 120                 125             


Val Asp Asn Glu Cys Ser Gly Val Lys Lys Cys Cys Ser Asn Gly Cys 
    130                 135                 140                 


Gly His Thr Cys Gln Val Pro Lys Thr Leu Tyr Lys Gly Val Pro Leu 
145                 150                 155                 160 


Lys Pro Arg Lys Glu Leu Arg Phe Thr Glu Leu Gln Ser Gly Gln Leu 
                165                 170                 175     


Glu Val Lys Trp Ser Ser Lys Phe Asn Ile Ser Ile Glu Pro Val Ile 
            180                 185                 190         


Tyr Val Val Gln Arg Arg Trp Asn Tyr Gly Ile His Pro Ser Glu Asp 
        195                 200                 205             


Asp Ala Thr His Trp Gln Thr Val Ala Gln Thr Thr Asp Glu Arg Val 
    210                 215                 220                 


Gln Leu Thr Asp Ile Arg Pro Ser Arg Trp Tyr Gln Phe Arg Val Ala 
225                 230                 235                 240 


Ala Val Asn Val His Gly Thr Arg Gly Phe Thr Ala Pro Ser Lys His 
                245                 250                 255     


Phe Arg Ser Ser Lys Asp Pro Ser Ala Pro Pro Ala Pro Ala Asn Leu 
            260                 265                 270         


Arg Leu Ala Asn Ser Thr Val Asn Ser Asp Gly Ser Val Thr Val Thr 
        275                 280                 285             


Ile Val Trp Asp Leu Pro Glu Glu Pro Asp Ile Pro Val His His Tyr 
    290                 295                 300                 


Lys Val Phe Trp Ser Trp Met Val Ser Ser Lys Ser Leu Val Pro Thr 
305                 310                 315                 320 


Lys Lys Lys Arg Arg Lys Thr Thr Asp Gly Phe Gln Asn Ser Val Ile 
                325                 330                 335     


Leu Glu Lys Leu Gln Pro Asp Cys Asp Tyr Val Val Glu Leu Gln Ala 
            340                 345                 350         


Ile Thr Tyr Trp Gly Gln Thr Arg Leu Lys Ser Ala Lys Val Ser Leu 
        355                 360                 365             


His Phe Thr Ser Thr His Ala Thr Asn Asn Lys Glu Gln Leu Val Lys 
    370                 375                 380                 


Thr Arg Lys Gly Gly Ile Gln Thr Gln Leu Pro Phe Gln Arg Arg Arg 
385                 390                 395                 400 


Pro Thr Arg Pro Leu Glu Val Gly Ala Pro Phe Tyr Gln Asp Gly Gln 
                405                 410                 415     


Leu Gln Val Lys Val Tyr Trp Lys Lys Thr Glu Asp Pro Thr Val Asn 
            420                 425                 430         


Arg Tyr His Val Arg Trp Phe Pro Glu Ala Cys Ala His Asn Arg Thr 
        435                 440                 445             


Thr Gly Ser Glu Ala Ser Ser Gly Met Thr His Glu Asn Tyr Ile Ile 
    450                 455                 460                 


Leu Gln Asp Leu Ser Phe Ser Cys Lys Tyr Lys Val Thr Val Gln Pro 
465                 470                 475                 480 


Ile Arg Pro Lys Ser His Ser Lys Ala Glu Ala Val Phe Phe Thr Thr 
                485                 490                 495     


Pro Pro Cys Ser Ala Leu Lys Gly Lys Ser His Lys Pro Ile Gly Cys 
            500                 505                 510         


Leu Gly Glu Ala Gly His Val Leu Ser Lys Val Leu Ala Lys Pro Glu 
        515                 520                 525             


Asn Leu Ser Ala Ser Phe Ile Val Gln Asp Val Asn Ile Thr Gly His 
    530                 535                 540                 


Phe Ser Trp Lys Met Ala Lys Ala Asn Leu Tyr Gln Pro Met Thr Gly 
545                 550                 555                 560 


Phe Gln Val Thr Trp Ala Glu Val Thr Thr Glu Ser Arg Gln Asn Ser 
                565                 570                 575     


Leu Pro Asn Ser Ile Ile Ser Gln Ser Gln Ile Leu Pro Ser Asp His 
            580                 585                 590         


Tyr Val Leu Thr Val Pro Asn Leu Arg Pro Ser Thr Leu Tyr Arg Leu 
        595                 600                 605             


Glu Val Gln Val Leu Thr Pro Gly Gly Glu Gly Pro Ala Thr Ile Lys 
    610                 615                 620                 


Thr Phe Arg Thr Pro Glu Leu Pro Pro Ser Ser Ala His Arg Ser His 
625                 630                 635                 640 


Leu Lys His Arg His Pro His His Tyr Lys Pro Ser Pro Glu Arg Tyr 
                645                 650                 655     


<210>  753
<211>  274
<212>  PRT
<213>  Homo Sapiens

<400>  753

Arg Pro Ser Pro Gly Pro Asp Tyr Leu Arg Arg Gly Trp Met Arg Leu 
1               5                   10                  15      


Leu Ala Glu Gly Glu Gly Cys Ala Pro Cys Arg Pro Glu Glu Cys Ala 
            20                  25                  30          


Ala Pro Arg Gly Cys Leu Ala Gly Arg Val Arg Asp Ala Cys Gly Cys 
        35                  40                  45              


Cys Trp Glu Cys Ala Asn Leu Glu Gly Gln Leu Cys Asp Leu Asp Pro 
    50                  55                  60                  


Ser Ala His Phe Tyr Gly His Cys Gly Glu Gln Leu Glu Cys Arg Leu 
65                  70                  75                  80  


Asp Thr Gly Gly Asp Leu Ser Arg Gly Glu Val Pro Glu Pro Leu Cys 
                85                  90                  95      


Ala Cys Arg Ser Gln Ser Pro Leu Cys Gly Ser Asp Gly His Thr Tyr 
            100                 105                 110         


Ser Gln Ile Cys Arg Leu Gln Glu Ala Ala Arg Ala Arg Pro Asp Ala 
        115                 120                 125             


Asn Leu Thr Val Ala His Pro Gly Pro Cys Glu Ser Gly Pro Gln Ile 
    130                 135                 140                 


Val Ser His Pro Tyr Asp Thr Trp Asn Val Thr Gly Gln Asp Val Ile 
145                 150                 155                 160 


Phe Gly Cys Glu Val Phe Ala Tyr Pro Met Ala Ser Ile Glu Trp Arg 
                165                 170                 175     


Lys Asp Gly Leu Asp Ile Gln Leu Pro Gly Asp Asp Pro His Ile Ser 
            180                 185                 190         


Val Gln Phe Arg Gly Gly Pro Gln Arg Phe Glu Val Thr Gly Trp Leu 
        195                 200                 205             


Gln Ile Gln Ala Val Arg Pro Ser Asp Glu Gly Thr Tyr Arg Cys Leu 
    210                 215                 220                 


Gly Arg Asn Ala Leu Gly Gln Val Glu Ala Pro Ala Ser Leu Thr Val 
225                 230                 235                 240 


Leu Thr Pro Asp Gln Leu Asn Ser Thr Gly Ile Pro Gln Leu Arg Ser 
                245                 250                 255     


Leu Asn Leu Val Pro Glu Glu Glu Ala Glu Ser Glu Glu Asn Asp Asp 
            260                 265                 270         


Tyr Tyr 
        


<210>  754
<211>  483
<212>  PRT
<213>  Homo Sapiens

<400>  754

Glu Thr Gly Gly Glu Arg Gln Leu Ser Pro Glu Lys Ser Glu Ile Trp 
1               5                   10                  15      


Gly Pro Gly Leu Lys Ala Asp Val Val Leu Pro Ala Arg Tyr Phe Tyr 
            20                  25                  30          


Ile Gln Ala Val Asp Thr Ser Gly Asn Lys Phe Thr Ser Ser Pro Gly 
        35                  40                  45              


Glu Lys Val Phe Gln Val Lys Val Ser Ala Pro Glu Glu Gln Phe Thr 
    50                  55                  60                  


Arg Val Gly Val Gln Val Leu Asp Arg Lys Asp Gly Ser Phe Ile Val 
65                  70                  75                  80  


Arg Tyr Arg Met Tyr Ala Ser Tyr Lys Asn Leu Lys Val Glu Val Lys 
                85                  90                  95      


Phe Gln Gly Gln His Val Ala Lys Ser Pro Tyr Ile Leu Lys Gly Pro 
            100                 105                 110         


Val Tyr His Glu Asn Cys Asp Cys Pro Leu Gln Asp Ser Ala Ala Trp 
        115                 120                 125             


Leu Arg Glu Met Asn Cys Pro Glu Thr Ile Ala Gln Ile Gln Arg Asp 
    130                 135                 140                 


Leu Ala His Phe Pro Ala Val Asp Pro Glu Lys Ile Ala Val Glu Ile 
145                 150                 155                 160 


Pro Lys Arg Phe Gly Gln Arg Gln Ser Leu Cys His Tyr Thr Leu Lys 
                165                 170                 175     


Asp Asn Lys Val Tyr Ile Lys Thr His Gly Glu His Val Gly Phe Arg 
            180                 185                 190         


Ile Phe Met Asp Ala Ile Leu Leu Ser Leu Thr Arg Lys Val Lys Met 
        195                 200                 205             


Pro Asp Val Glu Leu Phe Val Asn Leu Gly Asp Trp Pro Leu Glu Lys 
    210                 215                 220                 


Lys Lys Ser Asn Ser Asn Ile His Pro Ile Phe Ser Trp Cys Gly Ser 
225                 230                 235                 240 


Thr Asp Ser Lys Asp Ile Val Met Pro Thr Tyr Asp Leu Thr Asp Ser 
                245                 250                 255     


Val Leu Glu Thr Met Gly Arg Val Ser Leu Asp Met Met Ser Val Gln 
            260                 265                 270         


Ala Asn Thr Gly Pro Pro Trp Glu Ser Lys Asn Ser Thr Ala Val Trp 
        275                 280                 285             


Arg Gly Arg Asp Ser Arg Lys Glu Arg Leu Glu Leu Val Lys Leu Ser 
    290                 295                 300                 


Arg Lys His Pro Glu Leu Ile Asp Ala Ala Phe Thr Asn Phe Phe Phe 
305                 310                 315                 320 


Phe Lys His Asp Glu Asn Leu Tyr Gly Pro Ile Val Lys His Ile Ser 
                325                 330                 335     


Phe Phe Asp Phe Phe Lys His Lys Tyr Gln Ile Asn Ile Asp Gly Thr 
            340                 345                 350         


Val Ala Ala Tyr Arg Leu Pro Tyr Leu Leu Val Gly Asp Ser Val Val 
        355                 360                 365             


Leu Lys Gln Asp Ser Ile Tyr Tyr Glu His Phe Tyr Asn Glu Leu Gln 
    370                 375                 380                 


Pro Trp Lys His Tyr Ile Pro Val Lys Ser Asn Leu Ser Asp Leu Leu 
385                 390                 395                 400 


Glu Lys Leu Lys Trp Ala Lys Asp His Asp Glu Glu Ala Lys Lys Ile 
                405                 410                 415     


Ala Lys Ala Gly Gln Glu Phe Ala Arg Asn Asn Leu Met Gly Asp Asp 
            420                 425                 430         


Ile Phe Cys Tyr Tyr Phe Lys Leu Phe Gln Glu Tyr Ala Asn Leu Gln 
        435                 440                 445             


Val Ser Glu Pro Gln Ile Arg Glu Gly Met Lys Arg Val Glu Pro Gln 
    450                 455                 460                 


Thr Glu Asp Asp Leu Phe Pro Cys Thr Cys His Arg Lys Lys Thr Lys 
465                 470                 475                 480 


Asp Glu Leu 
            


<210>  755
<211>  487
<212>  PRT
<213>  Homo Sapiens

<400>  755

Gly Ala Pro Glu Val Leu Val Ser Ala Pro Arg Ser Leu Val Trp Gly 
1               5                   10                  15      


Pro Gly Leu Gln Ala Ala Val Val Leu Pro Val Arg Tyr Phe Tyr Leu 
            20                  25                  30          


Gln Ala Val Asn Ser Glu Gly Gln Asn Leu Thr Arg Ser Pro Ala Gly 
        35                  40                  45              


Glu Thr Pro Phe Lys Val Val Val Lys Ser Leu Ser Pro Lys Glu Leu 
    50                  55                  60                  


Val Arg Ile His Val Pro Lys Pro Leu Asp Arg Asn Asp Gly Thr Phe 
65                  70                  75                  80  


Leu Met Arg Tyr Arg Met Tyr Glu Thr Val Asp Glu Gly Leu Lys Ile 
                85                  90                  95      


Glu Val Leu Tyr Gly Asp Glu His Val Ala Gln Ser Pro Tyr Ile Leu 
            100                 105                 110         


Lys Gly Pro Val Tyr His Glu Tyr Cys Glu Cys Pro Glu Asp Pro Gln 
        115                 120                 125             


Ala Trp Gln Lys Thr Leu Ser Cys Pro Thr Lys Glu Pro Gln Ile Ala 
    130                 135                 140                 


Lys Asp Phe Ala Ser Phe Pro Ser Ile Asn Leu Gln Gln Met Leu Lys 
145                 150                 155                 160 


Glu Val Pro Lys Arg Phe Gly Asp Glu Arg Gly Ala Ile Val His Tyr 
                165                 170                 175     


Thr Ile Leu Asn Asn His Val Tyr Arg Arg Ser Leu Gly Lys Tyr Thr 
            180                 185                 190         


Asp Phe Lys Met Phe Ser Asp Glu Ile Leu Leu Ser Leu Thr Arg Lys 
        195                 200                 205             


Val Leu Leu Pro Asp Leu Glu Phe Tyr Val Asn Leu Gly Asp Trp Pro 
    210                 215                 220                 


Leu Glu His Arg Lys Val Asn Gly Thr Pro Ser Pro Ile Pro Ile Ile 
225                 230                 235                 240 


Ser Trp Cys Gly Ser Leu Asp Ser Arg Asp Val Val Leu Pro Thr Tyr 
                245                 250                 255     


Asp Ile Thr His Ser Met Leu Glu Ala Met Arg Gly Val Thr Asn Asp 
            260                 265                 270         


Leu Leu Ser Ile Gln Gly Asn Thr Gly Pro Ser Trp Ile Asn Lys Thr 
        275                 280                 285             


Glu Arg Ala Phe Phe Arg Gly Arg Asp Ser Leu Glu Glu Arg Leu Gln 
    290                 295                 300                 


Leu Val Gln Leu Ser Lys Glu Asn Pro Gln Leu Leu Asp Ala Gly Ile 
305                 310                 315                 320 


Thr Gly Tyr Phe Phe Phe Gln Glu Lys Glu Lys Glu Leu Gly Lys Ala 
                325                 330                 335     


Lys Leu Met Gly Phe Phe Asp Phe Phe Lys Tyr Lys Tyr Gln Val Asn 
            340                 345                 350         


Val Asp Gly Thr Val Ala Ala Tyr Arg Tyr Pro Tyr Leu Met Leu Gly 
        355                 360                 365             


Asp Ser Leu Val Leu Lys Gln Asp Ser Pro Tyr Tyr Glu His Phe Tyr 
    370                 375                 380                 


Met Ala Leu Glu Pro Trp Lys His Tyr Val Pro Ile Lys Arg Asn Leu 
385                 390                 395                 400 


Ser Asp Leu Leu Glu Lys Val Lys Trp Ala Lys Glu Asn Asp Glu Glu 
                405                 410                 415     


Ala Lys Lys Ile Ala Lys Glu Gly Gln Leu Met Ala Arg Asp Leu Leu 
            420                 425                 430         


Gln Pro His Arg Leu Tyr Cys Tyr Tyr Tyr Gln Val Leu Gln Lys Tyr 
        435                 440                 445             


Ala Glu Arg Gln Ser Ser Lys Pro Glu Val Arg Asp Gly Met Glu Leu 
    450                 455                 460                 


Val Pro Gln Pro Glu Asp Ser Thr Ala Ile Cys Gln Cys His Arg Lys 
465                 470                 475                 480 


Lys Pro Ser Arg Glu Glu Leu 
                485         


<210>  756
<211>  745
<212>  PRT
<213>  Homo Sapiens

<400>  756

Ala Ser Val Gly Leu Pro Ser Val Ser Leu Asp Leu Pro Arg Leu Ser 
1               5                   10                  15      


Ile Gln Lys Asp Ile Leu Thr Ile Lys Ala Asn Thr Thr Leu Gln Ile 
            20                  25                  30          


Thr Cys Arg Gly Gln Arg Asp Leu Asp Trp Leu Trp Pro Asn Asn Gln 
        35                  40                  45              


Ser Gly Ser Glu Gln Arg Val Glu Val Thr Glu Cys Ser Asp Gly Leu 
    50                  55                  60                  


Phe Cys Lys Thr Leu Thr Ile Pro Lys Val Ile Gly Asn Asp Thr Gly 
65                  70                  75                  80  


Ala Tyr Lys Cys Phe Tyr Arg Glu Thr Asp Leu Ala Ser Val Ile Tyr 
                85                  90                  95      


Val Tyr Val Gln Asp Tyr Arg Ser Pro Phe Ile Ala Ser Val Ser Asp 
            100                 105                 110         


Gln His Gly Val Val Tyr Ile Thr Glu Asn Lys Asn Lys Thr Val Val 
        115                 120                 125             


Ile Pro Cys Leu Gly Ser Ile Ser Asn Leu Asn Val Ser Leu Cys Ala 
    130                 135                 140                 


Arg Tyr Pro Glu Lys Arg Phe Val Pro Asp Gly Asn Arg Ile Ser Trp 
145                 150                 155                 160 


Asp Ser Lys Lys Gly Phe Thr Ile Pro Ser Tyr Met Ile Ser Tyr Ala 
                165                 170                 175     


Gly Met Val Phe Cys Glu Ala Lys Ile Asn Asp Glu Ser Tyr Gln Ser 
            180                 185                 190         


Ile Met Tyr Ile Val Val Val Val Gly Tyr Arg Ile Tyr Asp Val Val 
        195                 200                 205             


Leu Ser Pro Ser His Gly Ile Glu Leu Ser Val Gly Glu Lys Leu Val 
    210                 215                 220                 


Leu Asn Cys Thr Ala Arg Thr Glu Leu Asn Val Gly Ile Asp Phe Asn 
225                 230                 235                 240 


Trp Glu Tyr Pro Ser Ser Lys His Gln His Lys Lys Leu Val Asn Arg 
                245                 250                 255     


Asp Leu Lys Thr Gln Ser Gly Ser Glu Met Lys Lys Phe Leu Ser Thr 
            260                 265                 270         


Leu Thr Ile Asp Gly Ile Thr Arg Ser Asp Gln Gly Leu Tyr Thr Cys 
        275                 280                 285             


Ala Ala Ser Ser Gly Leu Met Thr Lys Lys Asn Ser Thr Phe Val Arg 
    290                 295                 300                 


Val His Glu Lys Pro Phe Val Ala Phe Gly Ser Gly Met Glu Ser Leu 
305                 310                 315                 320 


Val Glu Ala Thr Val Gly Glu Arg Val Arg Ile Pro Ala Lys Tyr Leu 
                325                 330                 335     


Gly Tyr Pro Pro Pro Glu Ile Lys Trp Tyr Lys Asn Gly Ile Pro Leu 
            340                 345                 350         


Glu Ser Asn His Thr Ile Lys Ala Gly His Val Leu Thr Ile Met Glu 
        355                 360                 365             


Val Ser Glu Arg Asp Thr Gly Asn Tyr Thr Val Ile Leu Thr Asn Pro 
    370                 375                 380                 


Ile Ser Lys Glu Lys Gln Ser His Val Val Ser Leu Val Val Tyr Val 
385                 390                 395                 400 


Pro Pro Gln Ile Gly Glu Lys Ser Leu Ile Ser Pro Val Asp Ser Tyr 
                405                 410                 415     


Gln Tyr Gly Thr Thr Gln Thr Leu Thr Cys Thr Val Tyr Ala Ile Pro 
            420                 425                 430         


Pro Pro His His Ile His Trp Tyr Trp Gln Leu Glu Glu Glu Cys Ala 
        435                 440                 445             


Asn Glu Pro Ser His Ala Val Ser Val Thr Asn Pro Tyr Pro Cys Glu 
    450                 455                 460                 


Glu Trp Arg Ser Val Glu Asp Phe Gln Gly Gly Asn Lys Ile Glu Val 
465                 470                 475                 480 


Asn Lys Asn Gln Phe Ala Leu Ile Glu Gly Lys Asn Lys Thr Val Ser 
                485                 490                 495     


Thr Leu Val Ile Gln Ala Ala Asn Val Ser Ala Leu Tyr Lys Cys Glu 
            500                 505                 510         


Ala Val Asn Lys Val Gly Arg Gly Glu Arg Val Ile Ser Phe His Val 
        515                 520                 525             


Thr Arg Gly Pro Glu Ile Thr Leu Gln Pro Asp Met Gln Pro Thr Glu 
    530                 535                 540                 


Gln Glu Ser Val Ser Leu Trp Cys Thr Ala Asp Arg Ser Thr Phe Glu 
545                 550                 555                 560 


Asn Leu Thr Trp Tyr Lys Leu Gly Pro Gln Pro Leu Pro Ile His Val 
                565                 570                 575     


Gly Glu Leu Pro Thr Pro Val Cys Lys Asn Leu Asp Thr Leu Trp Lys 
            580                 585                 590         


Leu Asn Ala Thr Met Phe Ser Asn Ser Thr Asn Asp Ile Leu Ile Met 
        595                 600                 605             


Glu Leu Lys Asn Ala Ser Leu Gln Asp Gln Gly Asp Tyr Val Cys Leu 
    610                 615                 620                 


Ala Gln Asp Arg Lys Thr Lys Lys Arg His Cys Val Val Arg Gln Leu 
625                 630                 635                 640 


Thr Val Leu Glu Arg Val Ala Pro Thr Ile Thr Gly Asn Leu Glu Asn 
                645                 650                 655     


Gln Thr Thr Ser Ile Gly Glu Ser Ile Glu Val Ser Cys Thr Ala Ser 
            660                 665                 670         


Gly Asn Pro Pro Pro Gln Ile Met Trp Phe Lys Asp Asn Glu Thr Leu 
        675                 680                 685             


Val Glu Asp Ser Gly Ile Val Leu Lys Asp Gly Asn Arg Asn Leu Thr 
    690                 695                 700                 


Ile Arg Arg Val Arg Lys Glu Asp Glu Gly Leu Tyr Thr Cys Gln Ala 
705                 710                 715                 720 


Cys Ser Val Leu Gly Cys Ala Lys Val Glu Ala Phe Phe Ile Ile Glu 
                725                 730                 735     


Gly Ala Gln Glu Lys Thr Asn Leu Glu 
            740                 745 


<210>  757
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  757

Arg Ser Val Arg Gln Val Tyr Glu Val His Asp Ser Asp Asp Trp Thr 
1               5                   10                  15      


Ile His Asp Phe Glu Cys Pro Met Glu Cys Phe Cys Pro Pro Ser Phe 
            20                  25                  30          


Pro Thr Ala Leu Tyr Cys Glu Asn Arg Gly Leu Lys Glu Ile Pro Ala 
        35                  40                  45              


Ile Pro Ser Arg Ile Trp Tyr Leu Tyr Leu Gln Asn Asn Leu Ile Glu 
    50                  55                  60                  


Thr Ile Pro Glu Lys Pro Phe Glu Asn Ala Thr Gln Leu Arg Trp Ile 
65                  70                  75                  80  


Asn Leu Asn Lys Asn Lys Ile Thr Asn Tyr Gly Ile Glu Lys Gly Ala 
                85                  90                  95      


Leu Ser Gln Leu Lys Lys Leu Leu Phe Leu Phe Leu Glu Asp Asn Glu 
            100                 105                 110         


Leu Glu Glu Val Pro Ser Pro Leu Pro Arg Ser Leu Glu Gln Leu Gln 
        115                 120                 125             


Leu Ala Arg Asn Lys Val Ser Arg Ile Pro Gln Gly Thr Phe Ser Asn 
    130                 135                 140                 


Leu Glu Asn Leu Thr Leu Leu Asp Leu Gln Asn Asn Lys Leu Val Asp 
145                 150                 155                 160 


Asn Ala Phe Gln Arg Asp Thr Phe Lys Gly Leu Lys Asn Leu Met Gln 
                165                 170                 175     


Leu Asn Met Ala Lys Asn Ala Leu Arg Asn Met Pro Pro Arg Leu Pro 
            180                 185                 190         


Ala Asn Thr Met Gln Leu Phe Leu Asp Asn Asn Ser Ile Glu Gly Ile 
        195                 200                 205             


Pro Glu Asn Tyr Phe Asn Val Ile Pro Lys Val Ala Phe Leu Arg Leu 
    210                 215                 220                 


Asn His Asn Lys Leu Ser Asp Glu Gly Leu Pro Ser Arg Gly Phe Asp 
225                 230                 235                 240 


Val Ser Ser Ile Leu Asp Leu Gln Leu Ser His Asn Gln Leu Thr Lys 
                245                 250                 255     


Val Pro Arg Ile Ser Ala His Leu Gln His Leu His Leu Asp His Asn 
            260                 265                 270         


Lys Ile Lys Ser Val Asn Val Ser Val Ile Cys Pro Ser Pro Ser Met 
        275                 280                 285             


Leu Pro Ala Glu Arg Asp Ser Phe Ser Tyr Gly Pro His Leu Arg Tyr 
    290                 295                 300                 


Leu Arg Leu Asp Gly Asn Glu Ile Lys Pro Pro Ile Pro Met Ala Leu 
305                 310                 315                 320 


Met Thr Cys Phe Arg Leu Leu Gln Ala Val Ile Ile 
                325                 330         


<210>  758
<211>  935
<212>  PRT
<213>  Homo Sapiens

<400>  758

Ala Arg Lys Gln Cys Ser Glu Gly Arg Thr Tyr Ser Asn Ala Val Ile 
1               5                   10                  15      


Ser Pro Asn Leu Glu Thr Thr Arg Ile Met Arg Val Ser His Thr Phe 
            20                  25                  30          


Pro Val Val Asp Cys Thr Ala Ala Cys Cys Asp Leu Ser Ser Cys Asp 
        35                  40                  45              


Leu Ala Trp Trp Phe Glu Gly Arg Cys Tyr Leu Val Ser Cys Pro His 
    50                  55                  60                  


Lys Glu Asn Cys Glu Pro Lys Lys Met Gly Pro Ile Arg Ser Tyr Leu 
65                  70                  75                  80  


Thr Phe Val Leu Arg Pro Val Gln Arg Pro Ala Gln Leu Leu Asp Tyr 
                85                  90                  95      


Gly Asp Met Met Leu Asn Arg Gly Ser Pro Ser Gly Ile Trp Gly Asp 
            100                 105                 110         


Ser Pro Glu Asp Ile Arg Lys Asp Leu Pro Phe Leu Gly Lys Asp Trp 
        115                 120                 125             


Gly Leu Glu Glu Met Ser Glu Tyr Ser Asp Asp Tyr Arg Glu Leu Glu 
    130                 135                 140                 


Lys Asp Leu Leu Gln Pro Ser Gly Lys Gln Glu Pro Arg Gly Ser Ala 
145                 150                 155                 160 


Glu Tyr Thr Asp Trp Gly Leu Leu Pro Gly Ser Glu Gly Ala Phe Asn 
                165                 170                 175     


Ser Ser Val Gly Asp Ser Pro Ala Val Pro Ala Glu Thr Gln Gln Asp 
            180                 185                 190         


Pro Glu Leu His Tyr Leu Asn Glu Ser Ala Ser Thr Pro Ala Pro Lys 
        195                 200                 205             


Leu Pro Glu Arg Ser Val Leu Leu Pro Leu Pro Thr Thr Pro Ser Ser 
    210                 215                 220                 


Gly Glu Val Leu Glu Lys Glu Lys Ala Ser Gln Leu Gln Glu Gln Ser 
225                 230                 235                 240 


Ser Asn Ser Ser Gly Lys Glu Val Leu Met Pro Ser His Ser Leu Pro 
                245                 250                 255     


Pro Ala Ser Leu Glu Leu Ser Ser Val Thr Val Glu Lys Ser Pro Val 
            260                 265                 270         


Leu Thr Val Thr Pro Gly Ser Thr Glu His Ser Ile Pro Thr Pro Pro 
        275                 280                 285             


Thr Ser Ala Ala Pro Ser Glu Ser Thr Pro Ser Glu Leu Pro Ile Ser 
    290                 295                 300                 


Pro Thr Thr Ala Pro Arg Thr Val Lys Glu Leu Thr Val Ser Ala Gly 
305                 310                 315                 320 


Asp Asn Leu Ile Ile Thr Leu Pro Asp Asn Glu Val Glu Leu Lys Ala 
                325                 330                 335     


Phe Val Ala Pro Ala Pro Pro Val Glu Thr Thr Tyr Asn Tyr Glu Trp 
            340                 345                 350         


Asn Leu Ile Ser His Pro Thr Asp Tyr Gln Gly Glu Ile Lys Gln Gly 
        355                 360                 365             


His Lys Gln Thr Leu Asn Leu Ser Gln Leu Ser Val Gly Leu Tyr Val 
    370                 375                 380                 


Phe Lys Val Thr Val Ser Ser Glu Asn Ala Phe Gly Glu Gly Phe Val 
385                 390                 395                 400 


Asn Val Thr Val Lys Pro Ala Arg Arg Val Asn Leu Pro Pro Val Ala 
                405                 410                 415     


Val Val Ser Pro Gln Leu Gln Glu Leu Thr Leu Pro Leu Thr Ser Ala 
            420                 425                 430         


Leu Ile Asp Gly Ser Gln Ser Thr Asp Asp Thr Glu Ile Val Ser Tyr 
        435                 440                 445             


His Trp Glu Glu Ile Asn Gly Pro Phe Ile Glu Glu Lys Thr Ser Val 
    450                 455                 460                 


Asp Ser Pro Val Leu Arg Leu Ser Asn Leu Asp Pro Gly Asn Tyr Ser 
465                 470                 475                 480 


Phe Arg Leu Thr Val Thr Asp Ser Asp Gly Ala Thr Asn Ser Thr Thr 
                485                 490                 495     


Ala Ala Leu Ile Val Asn Asn Ala Val Asp Tyr Pro Pro Val Ala Asn 
            500                 505                 510         


Ala Gly Pro Asn His Thr Ile Thr Leu Pro Gln Asn Ser Ile Thr Leu 
        515                 520                 525             


Asn Gly Asn Gln Ser Ser Asp Asp His Gln Ile Val Leu Tyr Glu Trp 
    530                 535                 540                 


Ser Leu Gly Pro Gly Ser Glu Gly Lys His Val Val Met Gln Gly Val 
545                 550                 555                 560 


Gln Thr Pro Tyr Leu His Leu Ser Ala Met Gln Glu Gly Asp Tyr Thr 
                565                 570                 575     


Phe Gln Leu Lys Val Thr Asp Ser Ser Arg Gln Gln Ser Thr Ala Val 
            580                 585                 590         


Val Thr Val Ile Val Gln Pro Glu Asn Asn Arg Pro Pro Val Ala Val 
        595                 600                 605             


Ala Gly Pro Asp Lys Glu Leu Ile Phe Pro Val Glu Ser Ala Thr Leu 
    610                 615                 620                 


Asp Gly Ser Ser Ser Ser Asp Asp His Gly Ile Val Phe Tyr His Trp 
625                 630                 635                 640 


Glu His Val Arg Gly Pro Ser Ala Val Glu Met Glu Asn Ile Asp Lys 
                645                 650                 655     


Ala Ile Ala Thr Val Thr Gly Leu Gln Val Gly Thr Tyr His Phe Arg 
            660                 665                 670         


Leu Thr Val Lys Asp Gln Gln Gly Leu Ser Ser Thr Ser Thr Leu Thr 
        675                 680                 685             


Val Ala Val Lys Lys Glu Asn Asn Ser Pro Pro Arg Ala Arg Ala Gly 
    690                 695                 700                 


Gly Arg His Val Leu Val Leu Pro Asn Asn Ser Ile Thr Leu Asp Gly 
705                 710                 715                 720 


Ser Arg Ser Thr Asp Asp Gln Arg Ile Val Ser Tyr Leu Trp Ile Arg 
                725                 730                 735     


Asp Gly Gln Ser Pro Ala Ala Gly Asp Val Ile Asp Gly Ser Asp His 
            740                 745                 750         


Ser Val Ala Leu Gln Leu Thr Asn Leu Val Glu Gly Val Tyr Thr Phe 
        755                 760                 765             


His Leu Arg Val Thr Asp Ser Gln Gly Ala Ser Asp Thr Asp Thr Ala 
    770                 775                 780                 


Thr Val Glu Val Gln Pro Asp Pro Arg Lys Ser Gly Leu Val Glu Leu 
785                 790                 795                 800 


Thr Leu Gln Val Gly Val Gly Gln Leu Thr Glu Gln Arg Lys Asp Thr 
                805                 810                 815     


Leu Val Arg Gln Leu Ala Val Leu Leu Asn Val Leu Asp Ser Asp Ile 
            820                 825                 830         


Lys Val Gln Lys Ile Arg Ala His Ser Asp Leu Ser Thr Val Ile Val 
        835                 840                 845             


Phe Tyr Val Gln Ser Arg Pro Pro Phe Lys Val Leu Lys Ala Ala Glu 
    850                 855                 860                 


Val Ala Arg Asn Leu His Met Arg Leu Ser Lys Glu Lys Ala Asp Phe 
865                 870                 875                 880 


Leu Leu Phe Lys Val Leu Arg Val Asp Thr Ala Gly Cys Leu Leu Lys 
                885                 890                 895     


Cys Ser Gly His Gly His Cys Asp Pro Leu Thr Lys Arg Cys Ile Cys 
            900                 905                 910         


Ser His Leu Trp Met Glu Asn Leu Ile Gln Arg Tyr Ile Trp Asp Gly 
        915                 920                 925             


Glu Ser Asn Cys Glu Trp Ser 
    930                 935 


<210>  759
<211>  882
<212>  PRT
<213>  Homo Sapiens

<400>  759

Glu Ser Arg Cys Gln Gln Gly Lys Thr Gln Phe Gly Val Gly Leu Arg 
1               5                   10                  15      


Ser Gly Gly Glu Asn His Leu Trp Leu Leu Glu Gly Thr Pro Ser Leu 
            20                  25                  30          


Gln Ser Cys Leu Ala Ala Cys Cys Gln Asp Ser Ala Cys His Val Phe 
        35                  40                  45              


Trp Trp Leu Glu Gly Met Cys Ile Gln Ala Asp Cys Ser Arg Pro Gln 
    50                  55                  60                  


Ser Cys Arg Ala Phe Arg Thr His Ser Ser Asn Ser Met Leu Val Phe 
65                  70                  75                  80  


Leu Lys Lys Phe Gln Thr Ala Asp Asp Leu Gly Phe Leu Pro Glu Asp 
                85                  90                  95      


Asp Val Pro His Leu Leu Gly Leu Gly Trp Asn Trp Ala Ser Trp Arg 
            100                 105                 110         


Gln Ser Pro Pro Arg Ala Ala Leu Arg Pro Ala Val Ser Ser Ser Asp 
        115                 120                 125             


Gln Gln Ser Leu Ile Arg Lys Leu Gln Lys Arg Gly Ser Pro Ser Asp 
    130                 135                 140                 


Val Val Thr Pro Ile Val Thr Gln His Ser Lys Val Asn Asp Ser Asn 
145                 150                 155                 160 


Glu Leu Gly Gly Leu Thr Thr Ser Gly Ser Ala Glu Val His Lys Ala 
                165                 170                 175     


Ile Thr Ile Ser Ser Pro Leu Thr Thr Asp Leu Thr Ala Glu Leu Ser 
            180                 185                 190         


Gly Gly Pro Lys Asn Val Ser Val Gln Pro Glu Ile Ser Glu Gly Leu 
        195                 200                 205             


Ala Thr Thr Pro Ser Thr Gln Gln Val Lys Ser Ser Glu Lys Thr Gln 
    210                 215                 220                 


Ile Ala Val Pro Gln Pro Val Ala Pro Ser Tyr Ser Tyr Ala Thr Pro 
225                 230                 235                 240 


Thr Pro Gln Ala Ser Phe Gln Ser Thr Ser Ala Pro Tyr Pro Val Ile 
                245                 250                 255     


Lys Glu Leu Val Val Ser Ala Gly Glu Ser Val Gln Ile Thr Leu Pro 
            260                 265                 270         


Lys Asn Glu Val Gln Leu Asn Ala Tyr Val Leu Gln Glu Pro Pro Lys 
        275                 280                 285             


Gly Glu Thr Tyr Thr Tyr Asp Trp Gln Leu Ile Thr His Pro Arg Asp 
    290                 295                 300                 


Tyr Ser Gly Glu Met Glu Gly Lys His Ser Gln Ile Leu Lys Leu Ser 
305                 310                 315                 320 


Lys Leu Thr Pro Gly Leu Tyr Glu Phe Lys Val Ile Val Glu Gly Gln 
                325                 330                 335     


Asn Ala His Gly Glu Gly Tyr Val Asn Val Thr Val Lys Pro Glu Pro 
            340                 345                 350         


Arg Lys Asn Arg Pro Pro Ile Ala Ile Val Ser Pro Gln Phe Gln Glu 
        355                 360                 365             


Ile Ser Leu Pro Thr Thr Ser Thr Val Ile Asp Gly Ser Gln Ser Thr 
    370                 375                 380                 


Asp Asp Asp Lys Ile Val Gln Tyr His Trp Glu Glu Leu Lys Gly Pro 
385                 390                 395                 400 


Leu Arg Glu Glu Lys Ile Ser Glu Asp Thr Ala Ile Leu Lys Leu Ser 
                405                 410                 415     


Lys Leu Val Pro Gly Asn Tyr Thr Phe Ser Leu Thr Val Val Asp Ser 
            420                 425                 430         


Asp Gly Ala Thr Asn Ser Thr Thr Ala Asn Leu Thr Val Asn Lys Ala 
        435                 440                 445             


Val Asp Tyr Pro Pro Val Ala Asn Ala Gly Pro Asn Gln Val Ile Thr 
    450                 455                 460                 


Leu Pro Gln Asn Ser Ile Thr Leu Phe Gly Asn Gln Ser Thr Asp Asp 
465                 470                 475                 480 


His Gly Ile Thr Ser Tyr Glu Trp Ser Leu Ser Pro Ser Ser Lys Gly 
                485                 490                 495     


Lys Val Val Glu Met Gln Gly Val Arg Thr Pro Thr Leu Gln Leu Ser 
            500                 505                 510         


Ala Met Gln Glu Gly Asp Tyr Thr Tyr Gln Leu Thr Val Thr Asp Thr 
        515                 520                 525             


Ile Gly Gln Gln Ala Thr Ala Gln Val Thr Val Ile Val Gln Pro Glu 
    530                 535                 540                 


Asn Asn Lys Pro Pro Gln Ala Asp Ala Gly Pro Asp Lys Glu Leu Thr 
545                 550                 555                 560 


Leu Pro Val Asp Ser Thr Thr Leu Asp Gly Ser Lys Ser Ser Asp Asp 
                565                 570                 575     


Gln Lys Ile Ile Ser Tyr Leu Trp Glu Lys Thr Gln Gly Pro Asp Gly 
            580                 585                 590         


Val Gln Leu Glu Asn Ala Asn Ser Ser Val Ala Thr Val Thr Gly Leu 
        595                 600                 605             


Gln Val Gly Thr Tyr Val Phe Thr Leu Thr Val Lys Asp Glu Arg Asn 
    610                 615                 620                 


Leu Gln Ser Gln Ser Ser Val Asn Val Ile Val Lys Glu Glu Ile Asn 
625                 630                 635                 640 


Lys Pro Pro Ile Ala Lys Ile Thr Gly Asn Val Val Ile Thr Leu Pro 
                645                 650                 655     


Thr Ser Thr Ala Glu Leu Asp Gly Ser Lys Ser Ser Asp Asp Lys Gly 
            660                 665                 670         


Ile Val Ser Tyr Leu Trp Thr Arg Asp Glu Gly Ser Pro Ala Ala Gly 
        675                 680                 685             


Glu Val Leu Asn His Ser Asp His His Pro Ile Leu Phe Leu Ser Asn 
    690                 695                 700                 


Leu Val Glu Gly Thr Tyr Thr Phe His Leu Lys Val Thr Asp Ala Lys 
705                 710                 715                 720 


Gly Glu Ser Asp Thr Asp Arg Thr Thr Val Glu Val Lys Pro Asp Pro 
                725                 730                 735     


Arg Lys Asn Asn Leu Val Glu Ile Ile Leu Asp Ile Asn Val Ser Gln 
            740                 745                 750         


Leu Thr Glu Arg Leu Lys Gly Met Phe Ile Arg Gln Ile Gly Val Leu 
        755                 760                 765             


Leu Gly Val Leu Asp Ser Asp Ile Ile Val Gln Lys Ile Gln Pro Tyr 
    770                 775                 780                 


Thr Glu Gln Ser Thr Lys Met Val Phe Phe Val Gln Asn Glu Pro Pro 
785                 790                 795                 800 


His Gln Ile Phe Lys Gly His Glu Val Ala Ala Met Leu Lys Ser Glu 
                805                 810                 815     


Leu Arg Lys Gln Lys Ala Asp Phe Leu Ile Phe Arg Ala Leu Glu Val 
            820                 825                 830         


Asn Thr Val Thr Cys Gln Leu Asn Cys Ser Asp His Gly His Cys Asp 
        835                 840                 845             


Ser Phe Thr Lys Arg Cys Ile Cys Asp Pro Phe Trp Met Glu Asn Phe 
    850                 855                 860                 


Ile Lys Val Gln Leu Arg Asp Gly Asp Ser Asn Cys Glu Trp Ser Val 
865                 870                 875                 880 


Leu Tyr 
        


<210>  760
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  760

His Glu Gly Val His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Arg 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Arg Phe Glu His Phe Leu Leu His Arg Glu Gly Lys Phe Lys Asp Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Thr His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Cys Arg Phe Ser Ala Gly Pro Lys Val Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Lys Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  761
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  761

His Glu Gly Val His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Arg Phe Gln His Phe Leu Leu His Arg Glu Gly Lys Phe Lys Asp Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Thr His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Phe Ser Ala Gly Pro Lys Val Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Leu 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Glu Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  762
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  762

His Glu Gly Val His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Arg Phe Gln His Phe Leu Leu His Arg Glu Gly Lys Phe Lys Asp Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Thr His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Phe Ser Ala Gly Pro Lys Val Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Leu 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Glu Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  763
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  763

Trp Ala His Val Gly Gly Gln Asp Lys Pro Phe Cys Ser Ala Trp Pro 
1               5                   10                  15      


Ser Ala Val Val Pro Gln Gly Gly His Val Thr Leu Arg Cys His Tyr 
            20                  25                  30          


Arg Arg Gly Phe Asn Ile Phe Thr Leu Tyr Lys Lys Asp Gly Val Pro 
        35                  40                  45              


Val Pro Glu Leu Tyr Asn Arg Ile Phe Trp Asn Ser Phe Leu Ile Ser 
    50                  55                  60                  


Pro Val Thr Pro Ala His Ala Gly Thr Tyr Arg Cys Arg Gly Phe His 
65                  70                  75                  80  


Pro His Ser Pro Thr Glu Trp Ser Ala Pro Ser Asn Pro Leu Val Ile 
                85                  90                  95      


Met Val Thr Gly Leu Tyr Glu Lys Pro Ser Leu Thr Ala Arg Pro Gly 
            100                 105                 110         


Pro Thr Val Arg Thr Gly Glu Asn Val Thr Leu Ser Cys Ser Ser Gln 
        115                 120                 125             


Ser Ser Phe Asp Ile Tyr His Leu Ser Arg Glu Gly Glu Ala His Glu 
    130                 135                 140                 


Leu Arg Leu Pro Ala Val Pro Ser Ile Asn Gly Thr Phe Gln Ala Asp 
145                 150                 155                 160 


Phe Pro Leu Gly Pro Ala Thr His Gly Glu Thr Tyr Arg Cys Phe Gly 
                165                 170                 175     


Ser Phe His Gly Ser Pro Tyr Glu Trp Ser Asp Ala Ser Asp Pro Leu 
            180                 185                 190         


Pro Val Ser Val Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser Pro Thr 
        195                 200                 205             


Glu Pro Ser Phe Lys Thr Gly Ile Ala Arg His Leu His 
    210                 215                 220     


<210>  764
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  764

His Glu Gly Gly Gln Asp Lys Pro Leu Leu Ser Ala Trp Pro Ser Ala 
1               5                   10                  15      


Val Val Pro Arg Gly Gly His Val Thr Leu Leu Cys Arg Ser Arg Leu 
            20                  25                  30          


Gly Phe Thr Ile Phe Ser Leu Tyr Lys Glu Asp Gly Val Pro Val Pro 
        35                  40                  45              


Glu Leu Tyr Asn Lys Ile Phe Trp Lys Ser Ile Leu Met Gly Pro Val 
    50                  55                  60                  


Thr Pro Ala His Ala Gly Thr Tyr Arg Cys Arg Gly Ser His Pro Arg 
65                  70                  75                  80  


Ser Pro Ile Glu Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Val Val 
                85                  90                  95      


Thr Gly Leu Phe Gly Lys Pro Ser Leu Ser Ala Gln Pro Gly Pro Thr 
            100                 105                 110         


Val Arg Thr Gly Glu Asn Val Ala Leu Ser Cys Ser Ser Arg Ser Ser 
        115                 120                 125             


Phe Asp Met Tyr His Leu Ser Arg Glu Gly Arg Ala His Glu Pro Arg 
    130                 135                 140                 


Leu Pro Ala Val Pro Ser Val Asp Gly Thr Phe Gln Ala Asp Phe Pro 
145                 150                 155                 160 


Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Thr Cys Phe Ser Ser Leu 
                165                 170                 175     


His Asp Ser Pro Tyr Glu Trp Ser Asp Pro Ser Asp Pro Leu Leu Val 
            180                 185                 190         


Ser Val Thr Gly Asn Ser Ser Ser Ser Ser Ser Ser Pro Thr Glu Pro 
        195                 200                 205             


Ser Ser Lys Thr Gly Ile Arg Arg His 
    210                 215         


<210>  765
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  765

His Glu Gly Gly Gln Asp Lys Pro Leu Leu Ser Ala Trp Pro Ser Ala 
1               5                   10                  15      


Val Val Pro Arg Gly Gly His Val Thr Leu Leu Cys Arg Ser Arg Leu 
            20                  25                  30          


Gly Phe Thr Ile Phe Ser Leu Tyr Lys Glu Asp Gly Val Pro Val Pro 
        35                  40                  45              


Glu Leu Tyr Asn Lys Ile Phe Trp Lys Ser Ile Leu Met Gly Pro Val 
    50                  55                  60                  


Thr Pro Ala His Ala Gly Thr Tyr Arg Cys Arg Gly Ser His Pro Arg 
65                  70                  75                  80  


Ser Pro Ile Glu Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Val Val 
                85                  90                  95      


Thr Gly Leu Phe Gly Lys Pro Ser Leu Ser Ala Gln Pro Gly Pro Thr 
            100                 105                 110         


Val Arg Thr Gly Glu Asn Val Ala Leu Ser Cys Ser Ser Arg Ser Ser 
        115                 120                 125             


Phe Asp Met Tyr His Leu Ser Arg Glu Gly Arg Ala His Glu Pro Arg 
    130                 135                 140                 


Leu Pro Ala Val Pro Ser Val Asp Gly Thr Phe Gln Ala Asp Phe Pro 
145                 150                 155                 160 


Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Thr Cys Phe Ser Ser Leu 
                165                 170                 175     


His Asp Ser Pro Tyr Glu Trp Ser Asp Pro Ser Asp Pro Leu Leu Val 
            180                 185                 190         


Ser Val Thr Gly Asn Ser Ser Ser Ser Ser Ser Ser Pro Thr Glu Pro 
        195                 200                 205             


Ser Ser Lys Thr Gly Ile Arg Arg His 
    210                 215         


<210>  766
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  766

His Glu Gly Val His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Arg Phe Glu His Phe Leu Leu His Arg Glu Gly Lys Tyr Lys Asp Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Thr His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Phe Ser Ala Gly Pro Lys Val Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Lys Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  767
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  767

His Glu Gly Phe Arg Arg Lys Pro Ser Leu Leu Ala His Pro Gly Arg 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Met Phe Glu His Phe Leu Leu His Arg Glu Gly Thr Phe Asn Asp Thr 
        35                  40                  45              


Leu Arg Leu Ile Gly Glu His Ile Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Arg Met Arg Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Pro His Ser Pro Tyr Gln Phe Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Trp Ser Ser Tyr Asp Met Tyr His Leu Ser Thr Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Phe Ser Ala Gly Pro Lys Val Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr Gln Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe His Asp Ser Pro Tyr Glu Trp Ser Lys Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Lys Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  768
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  768

Gln Glu Gly Val His Arg Lys Pro Ser Phe Leu Ala Leu Pro Gly His 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Met Phe Glu His Phe Leu Leu His Arg Glu Gly Lys Phe Asn Asn Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Pro Val Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Met Val Ile Ile Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Leu Pro Ala Val Arg Ser Ile Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ala Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Lys Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  769
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  769

Gln Glu Gly Val His Arg Lys Pro Ser Phe Leu Ala Leu Pro Gly His 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Met Phe Glu His Phe Leu Leu His Arg Glu Gly Lys Phe Asn Asn Thr 
        35                  40                  45              


Leu His Leu Ile Gly Glu His His Asp Gly Val Ser Lys Ala Asn Phe 
    50                  55                  60                  


Ser Ile Gly Pro Met Met Pro Val Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Met Val Ile Ile Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Leu Pro Ala Val Arg Ser Ile Asn Gly Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ala Pro Tyr Glu Trp Ser Asn Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Lys Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  770
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  770

His Glu Gly Phe Arg Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro 
1               5                   10                  15      


Leu Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val 
            20                  25                  30          


Met Phe Glu His Phe Leu Leu His Arg Glu Gly Thr Phe Asn His Thr 
        35                  40                  45              


Leu Arg Leu Ile Gly Glu His Ile Asp Gly Val Ser Lys Gly Asn Phe 
    50                  55                  60                  


Ser Ile Gly Arg Met Thr Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr 
65                  70                  75                  80  


Gly Ser Val Thr His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro 
                85                  90                  95      


Leu Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Pro Ala 
            100                 105                 110         


Gln Pro Gly Pro Thr Val Leu Ala Gly Glu Ser Val Thr Leu Ser Cys 
        115                 120                 125             


Ser Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Glu 
    130                 135                 140                 


Ala His Glu Arg Arg Leu Pro Ala Gly Pro Lys Val Asn Arg Thr Phe 
145                 150                 155                 160 


Gln Ala Asp Ser Pro Leu Asp Pro Ala Thr His Gly Gly Ala Tyr Arg 
                165                 170                 175     


Cys Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Lys Ser Ser 
            180                 185                 190         


Asp Pro Leu Leu Val Ser Val Thr Gly Asn Ser Ser Asn Ser Trp Pro 
        195                 200                 205             


Ser Pro Thr Glu Pro Ser Ser Glu Thr Gly Asn Pro Arg His Leu His 
    210                 215                 220                 


<210>  771
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  771

His Met Gly Gly Gln Asp Lys Pro Phe Leu Ser Ala Trp Pro Ser Ala 
1               5                   10                  15      


Val Val Pro Arg Gly Gly His Val Thr Leu Arg Cys His Tyr Arg His 
            20                  25                  30          


Arg Phe Asn Asn Phe Met Leu Tyr Lys Glu Asp Arg Ile His Val Pro 
        35                  40                  45              


Ile Phe His Gly Arg Ile Phe Gln Glu Gly Phe Asn Met Ser Pro Val 
    50                  55                  60                  


Thr Thr Ala His Ala Gly Asn Tyr Thr Cys Arg Gly Ser His Pro His 
65                  70                  75                  80  


Ser Pro Thr Gly Trp Ser Ala Pro Ser Asn Pro Met Val Ile Met Val 
                85                  90                  95      


Thr Gly Asn His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu 
            100                 105                 110         


Val Lys Ser Gly Glu Arg Val Ile Leu Gln Cys Trp Ser Asp Ile Met 
        115                 120                 125             


Phe Glu His Phe Phe Leu His Lys Glu Gly Ile Ser Lys Asp Pro Ser 
    130                 135                 140                 


Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe Ser 
145                 150                 155                 160 


Ile Gly Pro Met Met Leu Ala Leu Ala Gly Thr Tyr Arg Cys Tyr Gly 
                165                 170                 175     


Ser Val Thr His Thr Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro Leu 
            180                 185                 190         


Asp Ile Val Val Thr Gly Pro Tyr Glu Lys Pro Ser Leu Ser Ala Gln 
        195                 200                 205             


Pro Gly Pro Lys Val Gln Ala Gly Glu Ser Val Thr Leu Ser Cys Ser 
    210                 215                 220                 


Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Gly Ala 
225                 230                 235                 240 


His Glu Arg Arg Leu Pro Ala Val Arg Lys Val Asn Arg Thr Phe Gln 
                245                 250                 255     


Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg Cys 
            260                 265                 270         


Phe Gly Ser Phe Arg His Ser Pro Tyr Glu Trp Ser Asp Pro Ser Asp 
        275                 280                 285             


Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser 
    290                 295                 300                 


Pro Thr Glu Pro Ser Ser Lys Ser Gly Asn Pro Arg His Leu His 
305                 310                 315                 


<210>  772
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  772

Leu Met Gly Gly Gln Asp Lys Pro Phe Leu Ser Ala Arg Pro Ser Thr 
1               5                   10                  15      


Val Val Pro Arg Gly Gly His Val Ala Leu Gln Cys His Tyr Arg Arg 
            20                  25                  30          


Gly Phe Asn Asn Phe Met Leu Tyr Lys Glu Asp Arg Ser His Val Pro 
        35                  40                  45              


Ile Phe His Gly Arg Ile Phe Gln Glu Ser Phe Ile Met Gly Pro Val 
    50                  55                  60                  


Thr Pro Ala His Ala Gly Thr Tyr Arg Cys Arg Gly Ser Arg Pro His 
65                  70                  75                  80  


Ser Leu Thr Gly Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Met Val 
                85                  90                  95      


Thr Gly Asn His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu 
            100                 105                 110         


Leu Lys Ser Gly Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met 
        115                 120                 125             


Phe Glu His Phe Phe Leu His Arg Glu Gly Ile Ser Glu Asp Pro Ser 
    130                 135                 140                 


Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe Ser 
145                 150                 155                 160 


Ile Gly Pro Leu Met Pro Val Leu Ala Gly Thr Tyr Arg Cys Tyr Gly 
                165                 170                 175     


Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro Leu 
            180                 185                 190         


Asp Ile Val Ile Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala Gln 
        195                 200                 205             


Pro Gly Pro Thr Val Gln Ala Gly Glu Asn Val Thr Leu Ser Cys Ser 
    210                 215                 220                 


Ser Trp Ser Ser Tyr Asp Ile Tyr His Leu Ser Arg Glu Gly Glu Ala 
225                 230                 235                 240 


His Glu Arg Arg Leu Arg Ala Val Pro Lys Val Asn Arg Thr Phe Gln 
                245                 250                 255     


Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg Cys 
            260                 265                 270         


Phe Gly Ser Phe Arg Ala Leu Pro Cys Val Trp Ser Asn Ser Ser Asp 
        275                 280                 285             


Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser 
    290                 295                 300                 


Pro Thr Glu Pro Ser Ser Lys Ser Gly Ile Cys Arg His Leu His 
305                 310                 315                 


<210>  773
<211>  297
<212>  PRT
<213>  Homo Sapiens

<400>  773

Gln Asp Lys Pro Phe Leu Ser Ala Trp Pro Gly Thr Val Val Ser Glu 
1               5                   10                  15      


Gly Gln His Val Thr Leu Gln Cys Arg Ser His Leu Gly Phe Asn Glu 
            20                  25                  30          


Phe Ser Leu Ser Lys Glu Asp Gly Met Pro Val Pro Glu Leu Tyr Asn 
        35                  40                  45              


Arg Ile Phe Arg Asn Ser Phe Leu Met Gly Pro Val Thr Pro Ala His 
    50                  55                  60                  


Ala Gly Thr Tyr Arg Cys Cys Ser Ser His Pro His Ser Pro Thr Gly 
65                  70                  75                  80  


Trp Ser Ala Pro Ser Asn Pro Val Val Ile Met Val Thr Gly Val His 
                85                  90                  95      


Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu Val Lys Ser Gly 
            100                 105                 110         


Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Arg Phe Glu Arg Phe 
        115                 120                 125             


Leu Leu His Arg Glu Gly Ile Thr Glu Asp Pro Leu Arg Leu Val Gly 
    130                 135                 140                 


Gln Leu His Asp Ala Gly Ser Gln Val Asn Tyr Ser Met Gly Pro Met 
145                 150                 155                 160 


Thr Pro Ala Leu Ala Gly Thr Tyr Arg Cys Phe Gly Ser Val Thr His 
                165                 170                 175     


Leu Pro Tyr Glu Leu Ser Ala Pro Ser Asp Pro Leu Asp Ile Val Val 
            180                 185                 190         


Val Gly Leu Tyr Gly Lys Pro Ser Leu Ser Ala Gln Pro Gly Pro Thr 
        195                 200                 205             


Val Gln Ala Gly Glu Asn Val Thr Leu Ser Cys Ser Ser Arg Ser Leu 
    210                 215                 220                 


Phe Asp Ile Tyr His Leu Ser Arg Glu Ala Glu Ala Gly Glu Leu Arg 
225                 230                 235                 240 


Leu Thr Ala Val Leu Arg Val Asn Gly Thr Phe Gln Ala Asn Phe Pro 
                245                 250                 255     


Leu Gly Pro Val Thr His Gly Gly Asn Tyr Arg Cys Phe Gly Ser Phe 
            260                 265                 270         


Arg Ala Leu Pro His Ala Trp Ser Asp Pro Ser Asp Pro Leu Pro Val 
        275                 280                 285             


Ser Val Thr Gly Asn Ser Arg Tyr Leu 
    290                 295         


<210>  774
<211>  307
<212>  PRT
<213>  Homo Sapiens

<400>  774

His Glu Gly Gly Gln Asp Lys Pro Phe Leu Ser Ala Trp Pro Ser Pro 
1               5                   10                  15      


Val Val Ser Glu Gly Glu His Val Ala Leu Gln Cys Arg Ser Arg Leu 
            20                  25                  30          


Gly Phe Asn Glu Phe Ser Leu Ser Lys Glu Asp Gly Met Pro Val Pro 
        35                  40                  45              


Glu Leu Tyr Asn Arg Val Phe Arg Asn Thr Val Phe Ile Gly Pro Val 
    50                  55                  60                  


Thr Pro Ala His Ala Gly Thr Tyr Arg Cys Arg Gly Ser His Pro His 
65                  70                  75                  80  


Phe Leu Thr Gly Trp Ser Ala Pro Ser Asn Pro Leu Val Ile Met Val 
                85                  90                  95      


Thr Gly Val His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu 
            100                 105                 110         


Val Lys Ser Glu Glu Thr Val Ile Leu Gln Cys Trp Ser Asp Val Met 
        115                 120                 125             


Phe Glu His Phe Leu Leu His Arg Glu Gly Lys Phe Asn Asp Thr Leu 
    130                 135                 140                 


Arg Leu Thr Gly Glu Leu His Asp Gly Val Ser Lys Ala Asn Phe Ser 
145                 150                 155                 160 


Ile Gly Arg Met Thr Gln Asp Leu Ala Gly Thr Tyr Arg Cys Tyr Gly 
                165                 170                 175     


Ser Val Pro His Ser Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro Leu 
            180                 185                 190         


Asp Ile Val Ile Thr Gly Leu Cys Gly Lys Pro Ser Leu Ser Ala Gln 
        195                 200                 205             


Pro Arg Pro Met Val Lys Ala Gly Glu Ser Val Thr Leu Ser Cys Ser 
    210                 215                 220                 


Ser Arg Ser Ser Tyr Asp Ile Tyr His Leu Ser Arg Glu Gly Glu Ala 
225                 230                 235                 240 


His Glu Leu Arg Phe Pro Ala Val Pro Lys Val Asn Gly Thr Phe Gln 
                245                 250                 255     


Ala Asn Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg Cys 
            260                 265                 270         


Phe Gly Ser Phe Arg Asp Ser Pro Tyr Glu Trp Ser Asp Leu Ser Asp 
        275                 280                 285             


Pro Leu Leu Val Ser Val Thr Asp Ser Met Lys Glu Lys Gly Lys Asp 
    290                 295                 300                 


Val Ile Leu 
305         


<210>  775
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  775

His Met Gly Gly Gln Asp Lys Pro Phe Leu Ser Ala Trp Pro Ser Ala 
1               5                   10                  15      


Val Val Pro Arg Gly Gly His Val Thr Leu Arg Cys His Tyr Arg His 
            20                  25                  30          


Arg Phe Asn Asn Phe Met Leu Tyr Lys Glu Asp Arg Ile His Val Pro 
        35                  40                  45              


Ile Phe His Gly Arg Ile Phe Gln Glu Gly Phe Asn Met Ser Pro Val 
    50                  55                  60                  


Thr Thr Ala His Ala Gly Asn Tyr Thr Cys Arg Gly Ser His Pro His 
65                  70                  75                  80  


Ser Pro Thr Gly Trp Ser Ala Pro Ser Asn Pro Met Val Ile Met Val 
                85                  90                  95      


Thr Gly Asn His Arg Lys Pro Ser Leu Leu Ala His Pro Gly Pro Leu 
            100                 105                 110         


Val Lys Ser Gly Glu Arg Val Ile Leu Gln Cys Trp Ser Asp Ile Met 
        115                 120                 125             


Phe Glu His Phe Phe Leu His Lys Glu Trp Ile Ser Lys Asp Pro Ser 
    130                 135                 140                 


Arg Leu Val Gly Gln Ile His Asp Gly Val Ser Lys Ala Asn Phe Ser 
145                 150                 155                 160 


Ile Gly Ser Met Met Arg Ala Leu Ala Gly Thr Tyr Arg Cys Tyr Gly 
                165                 170                 175     


Ser Val Thr His Thr Pro Tyr Gln Leu Ser Ala Pro Ser Asp Pro Leu 
            180                 185                 190         


Asp Ile Val Val Thr Gly Leu Tyr Glu Lys Pro Ser Leu Ser Ala Gln 
        195                 200                 205             


Pro Gly Pro Lys Val Gln Ala Gly Glu Ser Val Thr Leu Ser Cys Ser 
    210                 215                 220                 


Ser Arg Ser Ser Tyr Asp Met Tyr His Leu Ser Arg Glu Gly Gly Ala 
225                 230                 235                 240 


His Glu Arg Arg Leu Pro Ala Val Arg Lys Val Asn Arg Thr Phe Gln 
                245                 250                 255     


Ala Asp Phe Pro Leu Gly Pro Ala Thr His Gly Gly Thr Tyr Arg Cys 
            260                 265                 270         


Phe Gly Ser Phe Arg His Ser Pro Tyr Glu Trp Ser Asp Pro Ser Asp 
        275                 280                 285             


Pro Leu Leu Val Ser Val Thr Gly Asn Pro Ser Ser Ser Trp Pro Ser 
    290                 295                 300                 


Pro Thr Glu Pro Ser Ser Lys Ser Gly Asn Leu Arg His Leu His 
305                 310                 315                 


<210>  776
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  776

Gln Lys Ile Cys Pro His Ala Gly Ala Gln Asp Lys Phe Ser Leu Ser 
1               5                   10                  15      


Ala Trp Pro Ser Pro Val Val Pro Leu Gly Gly Arg Val Thr Leu Ser 
            20                  25                  30          


Cys His Ser His Leu Arg Phe Val Ile Trp Thr Ile Phe Gln Thr Thr 
        35                  40                  45              


Gly Thr Arg Ser His Glu Leu His Thr Gly Leu Ser Asn Asn Ile Thr 
    50                  55                  60                  


Ile Ser Pro Val Thr Pro Glu His Ala Gly Thr Tyr Arg Cys Val Gly 
65                  70                  75                  80  


Ile Tyr Lys His Ala Ser Lys Trp Ser Ala Glu Ser Asn Ser Leu Lys 
                85                  90                  95      


Ile Ile Val Thr Gly Leu Phe Thr Lys Pro Ser Ile Ser Ala His Pro 
            100                 105                 110         


Ser Ser Leu Val His Ala Gly Ala Arg Val Ser Leu Arg Cys His Ser 
        115                 120                 125             


Glu Leu Ala Phe Asp Glu Phe Ile Leu Tyr Lys Glu Gly His Ile Gln 
    130                 135                 140                 


His Ser Gln Gln Leu Asp Gln Gly Met Glu Ala Gly Ile His Tyr Val 
145                 150                 155                 160 


Glu Ala Val Phe Ser Met Gly Pro Val Thr Pro Ala His Ala Gly Ala 
                165                 170                 175     


Tyr Arg Cys Cys Gly Cys Phe Ser His Ser Arg Tyr Glu Trp Ser Ala 
            180                 185                 190         


Pro Ser Asp Pro Leu Asp Ile Val Ile Thr Gly Lys Tyr Lys Lys Pro 
        195                 200                 205             


Ser Leu Ser Thr Gln Val Asp Pro Met Met Arg Leu Gly Glu Lys Leu 
    210                 215                 220                 


Thr Leu Phe Cys Ser Ser Glu Ile Ser Phe Asp Gln Tyr His Leu Phe 
225                 230                 235                 240 


Arg His Gly Val Ala His Gly Gln Trp Leu Ser Gly Gly Gln Arg His 
                245                 250                 255     


Arg Glu Ala Phe Gln Ala Asn Phe Ser Val Gly Arg Ala Thr Pro Val 
            260                 265                 270         


Pro Gly Gly Thr Tyr Arg Cys Tyr Gly Ser Phe Asn Asp Ser Pro Tyr 
        275                 280                 285             


Lys Pro Pro Val Thr Arg Cys Asn Phe Thr Pro Gln Glu Thr Leu Arg 
    290                 295                 300                 


Val Leu Leu Cys His Ser Gln Asn Pro Pro Leu Asn Leu Thr His Leu 
305                 310                 315                 320 


Ala Leu Lys Asp Ser Pro Ala Thr Cys Ile Cys Ser Leu Asp Ser Gln 
                325                 330                 335     


<210>  777
<211>  483
<212>  PRT
<213>  Homo Sapiens

<400>  777

Gln Gly Thr Gln Thr Arg Phe Ser Gln Glu Pro Ala Asp Gln Thr Val 
1               5                   10                  15      


Val Ala Gly Gln Arg Ala Val Leu Pro Cys Val Leu Leu Asn Tyr Ser 
            20                  25                  30          


Gly Ile Val Gln Trp Thr Lys Asp Gly Leu Ala Leu Gly Met Gly Gln 
        35                  40                  45              


Gly Leu Lys Ala Trp Pro Arg Tyr Arg Val Val Gly Ser Ala Asp Ala 
    50                  55                  60                  


Gly Gln Tyr Asn Leu Glu Ile Thr Asp Ala Glu Leu Ser Asp Asp Ala 
65                  70                  75                  80  


Ser Tyr Glu Cys Gln Ala Thr Glu Ala Ala Leu Arg Ser Arg Arg Ala 
                85                  90                  95      


Lys Leu Thr Val Leu Ile Pro Pro Glu Asp Thr Arg Ile Asp Gly Gly 
            100                 105                 110         


Pro Val Ile Leu Leu Gln Ala Gly Thr Pro His Asn Leu Thr Cys Arg 
        115                 120                 125             


Ala Phe Asn Ala Lys Pro Ala Ala Thr Ile Ile Trp Phe Arg Asp Gly 
    130                 135                 140                 


Thr Gln Gln Glu Gly Ala Val Ala Ser Thr Glu Leu Leu Lys Asp Gly 
145                 150                 155                 160 


Lys Arg Glu Thr Thr Val Ser Gln Leu Leu Ile Asn Pro Thr Asp Leu 
                165                 170                 175     


Asp Ile Gly Arg Val Phe Thr Cys Arg Ser Met Asn Glu Ala Ile Pro 
            180                 185                 190         


Ser Gly Lys Glu Thr Ser Ile Glu Leu Asp Val His His Pro Pro Thr 
        195                 200                 205             


Val Thr Leu Ser Ile Glu Pro Gln Thr Val Gln Glu Gly Glu Arg Val 
    210                 215                 220                 


Val Phe Thr Cys Gln Ala Thr Ala Asn Pro Glu Ile Leu Gly Tyr Arg 
225                 230                 235                 240 


Trp Ala Lys Gly Gly Phe Leu Ile Glu Asp Ala His Glu Ser Arg Tyr 
                245                 250                 255     


Glu Thr Asn Val Asp Tyr Ser Phe Phe Thr Glu Pro Val Ser Cys Glu 
            260                 265                 270         


Val His Asn Lys Val Gly Ser Thr Asn Val Ser Thr Leu Val Asn Val 
        275                 280                 285             


His Phe Ala Pro Arg Ile Val Val Asp Pro Lys Pro Thr Thr Thr Asp 
    290                 295                 300                 


Ile Gly Ser Asp Val Thr Leu Thr Cys Val Trp Val Gly Asn Pro Pro 
305                 310                 315                 320 


Leu Thr Leu Thr Trp Thr Lys Lys Asp Ser Asn Met Val Leu Ser Asn 
                325                 330                 335     


Ser Asn Gln Leu Leu Leu Lys Ser Val Thr Gln Ala Asp Ala Gly Thr 
            340                 345                 350         


Tyr Thr Cys Arg Ala Ile Val Pro Arg Ile Gly Val Ala Glu Arg Glu 
        355                 360                 365             


Val Pro Leu Tyr Val Asn Gly Pro Pro Ile Ile Ser Ser Glu Ala Val 
    370                 375                 380                 


Gln Tyr Ala Val Arg Gly Asp Gly Gly Lys Val Glu Cys Phe Ile Gly 
385                 390                 395                 400 


Ser Thr Pro Pro Pro Asp Arg Ile Ala Trp Ala Trp Lys Glu Asn Phe 
                405                 410                 415     


Leu Glu Val Gly Thr Leu Glu Arg Tyr Thr Val Glu Arg Thr Asn Ser 
            420                 425                 430         


Gly Ser Gly Val Leu Ser Thr Leu Thr Ile Asn Asn Val Met Glu Ala 
        435                 440                 445             


Asp Phe Gln Thr His Tyr Asn Cys Thr Ala Trp Asn Ser Phe Gly Pro 
    450                 455                 460                 


Gly Thr Ala Ile Ile Gln Leu Glu Glu Arg Glu Val Leu Pro Val Gly 
465                 470                 475                 480 


Ile Ile Ala 
            


<210>  778
<211>  470
<212>  PRT
<213>  Homo Sapiens

<400>  778

Gly Pro Ser Pro His Phe Leu Gln Gln Pro Glu Asp Leu Val Val Leu 
1               5                   10                  15      


Leu Gly Glu Glu Ala Arg Leu Pro Cys Ala Leu Gly Ala Tyr Trp Gly 
            20                  25                  30          


Leu Val Gln Trp Thr Lys Ser Gly Leu Ala Leu Gly Gly Gln Arg Asp 
        35                  40                  45              


Leu Pro Gly Trp Ser Arg Tyr Trp Ile Ser Gly Asn Ala Ala Asn Gly 
    50                  55                  60                  


Gln His Asp Leu His Ile Arg Pro Val Glu Leu Glu Asp Glu Ala Ser 
65                  70                  75                  80  


Tyr Glu Cys Gln Ala Thr Gln Ala Gly Leu Arg Ser Arg Pro Ala Gln 
                85                  90                  95      


Leu His Val Leu Val Pro Pro Glu Ala Pro Gln Val Leu Gly Gly Pro 
            100                 105                 110         


Ser Val Ser Leu Val Ala Gly Val Pro Ala Asn Leu Thr Cys Arg Ser 
        115                 120                 125             


Arg Gly Asp Ala Arg Pro Thr Pro Glu Leu Leu Trp Phe Arg Asp Gly 
    130                 135                 140                 


Val Leu Leu Asp Gly Ala Thr Phe His Gln Thr Leu Leu Lys Glu Gly 
145                 150                 155                 160 


Thr Pro Gly Ser Val Glu Ser Thr Leu Thr Leu Pro Thr Gly Arg Asp 
                165                 170                 175     


Thr Ala Ile Thr Leu Ser Leu Gln Tyr Pro Pro Glu Val Thr Leu Ser 
            180                 185                 190         


Ala Ser Pro His Thr Val Gln Glu Gly Glu Lys Val Ile Phe Leu Cys 
        195                 200                 205             


Gln Ala Thr Ala Gln Pro Pro Val Thr Gly Tyr Arg Trp Ala Lys Gly 
    210                 215                 220                 


Gly Ser Pro Val Leu Gly Ala Arg Gly Pro Arg Leu Glu Val Val Ala 
225                 230                 235                 240 


Asp Ala Ser Phe Leu Thr Glu Pro Val Ser Cys Glu Val Ser Asn Ala 
                245                 250                 255     


Val Gly Ser Ala Asn Arg Ser Thr Ala Leu Asp Val Leu Phe Gly Pro 
            260                 265                 270         


Ile Leu Gln Ala Lys Pro Glu Pro Val Ser Val Asp Val Gly Glu Asp 
        275                 280                 285             


Ala Ser Phe Ser Cys Ala Trp Arg Gly Asn Pro Leu Pro Arg Val Thr 
    290                 295                 300                 


Trp Thr Arg Arg Gly Gly Ala Gln Val Leu Gly Ser Gly Ala Thr Leu 
305                 310                 315                 320 


Arg Leu Pro Ser Val Gly Pro Glu Asp Ala Gly Asp Tyr Val Cys Arg 
                325                 330                 335     


Ala Glu Ala Gly Leu Ser Gly Leu Arg Gly Gly Ala Ala Glu Ala Arg 
            340                 345                 350         


Leu Thr Val Asn Ala Pro Pro Val Val Thr Ala Leu His Ser Ala Pro 
        355                 360                 365             


Ala Phe Leu Arg Gly Pro Ala Arg Leu Gln Cys Leu Val Phe Ala Ser 
    370                 375                 380                 


Pro Ala Pro Asp Ala Val Val Trp Ser Trp Asp Glu Gly Phe Leu Glu 
385                 390                 395                 400 


Ala Gly Ser Gln Gly Arg Phe Leu Val Glu Thr Phe Pro Ala Pro Glu 
                405                 410                 415     


Ser Arg Gly Gly Leu Gly Pro Gly Leu Ile Ser Val Leu His Ile Ser 
            420                 425                 430         


Gly Thr Gln Glu Ser Asp Phe Ser Arg Ser Phe Asn Cys Ser Ala Arg 
        435                 440                 445             


Asn Arg Leu Gly Glu Gly Gly Ala Gln Ala Ser Leu Gly Arg Arg Asp 
    450                 455                 460                 


Leu Leu Pro Thr Val Arg 
465                 470 


<210>  779
<211>  514
<212>  PRT
<213>  Homo Sapiens

<400>  779

Leu Gln Lys Arg Gly Cys Cys Leu Val Leu Gly Tyr Met Ala Lys Asp 
1               5                   10                  15      


Lys Phe Arg Arg Met Asn Glu Gly Gln Val Tyr Ser Phe Ser Gln Gln 
            20                  25                  30          


Pro Gln Asp Gln Val Val Val Ser Gly Gln Pro Val Thr Leu Leu Cys 
        35                  40                  45              


Ala Ile Pro Glu Tyr Asp Gly Phe Val Leu Trp Ile Lys Asp Gly Leu 
    50                  55                  60                  


Ala Leu Gly Val Gly Arg Asp Leu Ser Ser Tyr Pro Gln Tyr Leu Val 
65                  70                  75                  80  


Val Gly Asn His Leu Ser Gly Glu His His Leu Lys Ile Leu Arg Ala 
                85                  90                  95      


Glu Leu Gln Asp Asp Ala Val Tyr Glu Cys Gln Ala Ile Gln Ala Ala 
            100                 105                 110         


Ile Arg Ser Arg Pro Ala Arg Leu Thr Val Leu Val Pro Pro Asp Asp 
        115                 120                 125             


Pro Val Ile Leu Gly Gly Pro Val Ile Ser Leu Arg Ala Gly Asp Pro 
    130                 135                 140                 


Leu Asn Leu Thr Cys His Ala Asp Asn Ala Lys Pro Ala Ala Ser Ile 
145                 150                 155                 160 


Ile Trp Leu Arg Lys Gly Glu Val Ile Asn Gly Ala Thr Tyr Ser Lys 
                165                 170                 175     


Thr Leu Leu Arg Asp Gly Lys Arg Glu Ser Ile Val Ser Thr Leu Phe 
            180                 185                 190         


Ile Ser Pro Gly Asp Val Glu Asn Gly Gln Ser Ile Val Cys Arg Ala 
        195                 200                 205             


Thr Asn Lys Ala Ile Pro Gly Gly Lys Glu Thr Ser Val Thr Ile Asp 
    210                 215                 220                 


Ile Gln His Pro Pro Leu Val Asn Leu Ser Val Glu Pro Gln Pro Val 
225                 230                 235                 240 


Leu Glu Asp Asn Val Val Thr Phe His Cys Ser Ala Lys Ala Asn Pro 
                245                 250                 255     


Ala Val Thr Gln Tyr Arg Trp Ala Lys Arg Gly Gln Ile Ile Lys Glu 
            260                 265                 270         


Ala Ser Gly Glu Val Tyr Arg Thr Thr Val Asp Tyr Thr Tyr Phe Ser 
        275                 280                 285             


Glu Pro Val Ser Cys Glu Val Thr Asn Ala Leu Gly Ser Thr Asn Leu 
    290                 295                 300                 


Ser Arg Thr Val Asp Val Tyr Phe Gly Pro Arg Met Thr Thr Glu Pro 
305                 310                 315                 320 


Gln Ser Leu Leu Val Asp Leu Gly Ser Asp Ala Ile Phe Ser Cys Ala 
                325                 330                 335     


Trp Thr Gly Asn Pro Ser Leu Thr Ile Val Trp Met Lys Arg Gly Ser 
            340                 345                 350         


Gly Val Val Leu Ser Asn Glu Lys Thr Leu Thr Leu Lys Ser Val Arg 
        355                 360                 365             


Gln Glu Asp Ala Gly Lys Tyr Val Cys Arg Ala Val Val Pro Arg Val 
    370                 375                 380                 


Gly Ala Gly Glu Arg Glu Val Thr Leu Thr Val Asn Gly Pro Pro Ile 
385                 390                 395                 400 


Ile Ser Ser Thr Gln Thr Gln His Ala Leu His Gly Glu Lys Gly Gln 
                405                 410                 415     


Ile Lys Cys Phe Ile Arg Ser Thr Pro Pro Pro Asp Arg Ile Ala Trp 
            420                 425                 430         


Ser Trp Lys Glu Asn Val Leu Glu Ser Gly Thr Ser Gly Arg Tyr Thr 
        435                 440                 445             


Val Glu Thr Ile Ser Thr Glu Glu Gly Val Ile Ser Thr Leu Thr Ile 
    450                 455                 460                 


Ser Asn Ile Val Arg Ala Asp Phe Gln Thr Ile Tyr Asn Cys Thr Ala 
465                 470                 475                 480 


Trp Asn Ser Phe Gly Ser Asp Thr Glu Ile Ile Arg Leu Lys Glu Gln 
                485                 490                 495     


Gly Ser Glu Met Lys Ser Gly Ala Gly Leu Glu Ala Glu Ser Val Pro 
            500                 505                 510         


Met Ala 
        


<210>  780
<211>  499
<212>  PRT
<213>  Homo Sapiens

<400>  780

Gln Pro Ser Val Ser Pro Gly Glu Pro Ser Pro Pro Ser Ile His Pro 
1               5                   10                  15      


Gly Lys Ser Asp Leu Ile Val Arg Val Gly Asp Glu Ile Arg Leu Leu 
            20                  25                  30          


Cys Thr Asp Pro Gly Phe Val Lys Trp Thr Phe Glu Ile Leu Asp Glu 
        35                  40                  45              


Thr Asn Glu Asn Lys Gln Asn Glu Trp Ile Thr Glu Lys Ala Glu Ala 
    50                  55                  60                  


Thr Asn Thr Gly Lys Tyr Thr Cys Thr Asn Lys His Gly Leu Ser Asn 
65                  70                  75                  80  


Ser Ile Tyr Val Phe Val Arg Asp Pro Ala Lys Leu Phe Leu Val Asp 
                85                  90                  95      


Arg Ser Leu Tyr Gly Lys Glu Asp Asn Asp Thr Leu Val Arg Cys Pro 
            100                 105                 110         


Leu Thr Asp Pro Glu Val Thr Asn Tyr Ser Leu Lys Gly Cys Gln Gly 
        115                 120                 125             


Lys Pro Leu Pro Lys Asp Leu Arg Phe Ile Pro Asp Pro Lys Ala Gly 
    130                 135                 140                 


Ile Met Ile Lys Ser Val Lys Arg Ala Tyr His Arg Leu Cys Leu His 
145                 150                 155                 160 


Cys Ser Val Asp Gln Glu Gly Lys Ser Val Leu Ser Glu Lys Phe Ile 
                165                 170                 175     


Leu Lys Val Arg Pro Ala Phe Lys Ala Val Pro Val Val Ser Val Ser 
            180                 185                 190         


Lys Ala Ser Tyr Leu Leu Arg Glu Gly Glu Glu Phe Thr Val Thr Cys 
        195                 200                 205             


Thr Ile Lys Asp Val Ser Ser Ser Val Tyr Ser Thr Trp Lys Arg Glu 
    210                 215                 220                 


Asn Ser Gln Thr Lys Leu Gln Glu Lys Tyr Asn Ser Trp His His Gly 
225                 230                 235                 240 


Asp Phe Asn Tyr Glu Arg Gln Ala Thr Leu Thr Ile Ser Ser Ala Arg 
                245                 250                 255     


Val Asn Asp Ser Gly Val Phe Met Cys Tyr Ala Asn Asn Thr Phe Gly 
            260                 265                 270         


Ser Ala Asn Val Thr Thr Thr Leu Glu Val Val Asp Lys Gly Phe Ile 
        275                 280                 285             


Asn Ile Phe Pro Met Ile Asn Thr Thr Val Phe Val Asn Asp Gly Glu 
    290                 295                 300                 


Asn Val Asp Leu Ile Val Glu Tyr Glu Ala Phe Pro Lys Pro Glu His 
305                 310                 315                 320 


Gln Gln Trp Ile Tyr Met Asn Arg Thr Phe Thr Asp Lys Trp Glu Asp 
                325                 330                 335     


Tyr Pro Lys Ser Glu Asn Glu Ser Asn Ile Arg Tyr Val Ser Glu Leu 
            340                 345                 350         


His Leu Thr Arg Leu Lys Gly Thr Glu Gly Gly Thr Tyr Thr Phe Leu 
        355                 360                 365             


Val Ser Asn Ser Asp Val Asn Ala Ala Ile Ala Phe Asn Val Tyr Val 
    370                 375                 380                 


Asn Thr Lys Pro Glu Ile Leu Thr Tyr Asp Arg Leu Val Asn Gly Met 
385                 390                 395                 400 


Leu Gln Cys Val Ala Ala Gly Phe Pro Glu Pro Thr Ile Asp Trp Tyr 
                405                 410                 415     


Phe Cys Pro Gly Thr Glu Gln Arg Cys Ser Ala Ser Val Leu Pro Val 
            420                 425                 430         


Asp Val Gln Thr Leu Asn Ser Ser Gly Pro Pro Phe Gly Lys Leu Val 
        435                 440                 445             


Val Gln Ser Ser Ile Asp Ser Ser Ala Phe Lys His Asn Gly Thr Val 
    450                 455                 460                 


Glu Cys Lys Ala Tyr Asn Asp Val Gly Lys Thr Ser Ala Tyr Phe Asn 
465                 470                 475                 480 


Phe Ala Phe Lys Gly Asn Asn Lys Glu Gln Ile His Pro His Thr Leu 
                485                 490                 495     


Phe Thr Pro 
            


<210>  781
<211>  165
<212>  PRT
<213>  Homo Sapiens

<400>  781

Glu Gly Ile Cys Arg Asn Arg Val Thr Asn Asn Val Lys Asp Val Thr 
1               5                   10                  15      


Lys Leu Val Ala Asn Leu Pro Lys Asp Tyr Met Ile Thr Leu Lys Tyr 
            20                  25                  30          


Val Pro Gly Met Asp Val Leu Pro Ser His Cys Trp Ile Ser Glu Met 
        35                  40                  45              


Val Val Gln Leu Ser Asp Ser Leu Thr Asp Leu Leu Asp Lys Phe Ser 
    50                  55                  60                  


Asn Ile Ser Glu Gly Leu Ser Asn Tyr Ser Ile Ile Asp Lys Leu Val 
65                  70                  75                  80  


Asn Ile Val Asp Asp Leu Val Glu Cys Val Lys Glu Asn Ser Ser Lys 
                85                  90                  95      


Asp Leu Lys Lys Ser Phe Lys Ser Pro Glu Pro Arg Leu Phe Thr Pro 
            100                 105                 110         


Glu Glu Phe Phe Arg Ile Phe Asn Arg Ser Ile Asp Ala Phe Lys Asp 
        115                 120                 125             


Phe Val Val Ala Ser Glu Thr Ser Asp Cys Val Val Ser Ser Thr Leu 
    130                 135                 140                 


Ser Pro Glu Lys Asp Ser Arg Val Ser Val Thr Lys Pro Phe Met Leu 
145                 150                 155                 160 


Pro Pro Val Ala Ala 
                165 


<210>  782
<211>  159
<212>  PRT
<213>  Homo Sapiens

<400>  782

Gln Lys Ser Ser Ile Glu Lys Cys Ser Val Asp Ile Gln Gln Ser Arg 
1               5                   10                  15      


Asn Lys Thr Thr Glu Arg Pro Gly Leu Leu Asn Cys Pro Ile Tyr Trp 
            20                  25                  30          


Gln Gln Leu Arg Glu Lys Cys Leu Leu Phe Ser His Thr Val Asn Pro 
        35                  40                  45              


Trp Asn Asn Ser Leu Ala Asp Cys Ser Thr Lys Glu Ser Ser Leu Leu 
    50                  55                  60                  


Leu Ile Arg Asp Lys Asp Glu Leu Ile His Thr Gln Asn Leu Ile Arg 
65                  70                  75                  80  


Asp Lys Ala Ile Leu Phe Trp Ile Gly Leu Asn Phe Ser Leu Ser Glu 
                85                  90                  95      


Lys Asn Trp Lys Trp Ile Asn Gly Ser Phe Leu Asn Ser Asn Asp Leu 
            100                 105                 110         


Glu Ile Arg Gly Asp Ala Lys Glu Asn Ser Cys Ile Ser Ile Ser Gln 
        115                 120                 125             


Thr Ser Val Tyr Ser Glu Tyr Cys Ser Thr Glu Ile Arg Trp Ile Cys 
    130                 135                 140                 


Gln Lys Glu Leu Thr Pro Val Arg Asn Lys Val Tyr Pro Asp Ser 
145                 150                 155                 


<210>  783
<211>  140
<212>  PRT
<213>  Homo Sapiens

<400>  783

Pro Ser Thr Leu Ile Gln Arg His Asn Asn Ser Ser Leu Asn Thr Arg 
1               5                   10                  15      


Thr Gln Lys Ala Arg His Cys Gly His Cys Pro Glu Glu Trp Ile Thr 
            20                  25                  30          


Tyr Ser Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg Arg Thr Trp Glu 
        35                  40                  45              


Glu Ser Leu Leu Ala Cys Thr Ser Lys Asn Ser Ser Leu Leu Ser Ile 
    50                  55                  60                  


Asp Asn Glu Glu Glu Met Lys Phe Leu Ser Ile Ile Ser Pro Ser Ser 
65                  70                  75                  80  


Trp Ile Gly Val Phe Arg Asn Ser Ser His His Pro Trp Val Thr Met 
                85                  90                  95      


Asn Gly Leu Ala Phe Lys His Glu Ile Lys Asp Ser Asp Asn Ala Glu 
            100                 105                 110         


Leu Asn Cys Ala Val Leu Gln Val Asn Arg Leu Lys Ser Ala Gln Cys 
        115                 120                 125             


Gly Ser Ser Ile Ile Tyr His Cys Lys His Lys Leu 
    130                 135                 140 


<210>  784
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  784

Ile Pro Phe Leu Glu Gln Asn Asn Ser Ser Pro Asn Thr Arg Thr Gln 
1               5                   10                  15      


Lys Ala Arg His Cys Gly His Cys Pro Glu Glu Trp Ile Thr Tyr Ser 
            20                  25                  30          


Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg Arg Thr Trp Glu Glu Ser 
        35                  40                  45              


Leu Leu Ala Cys Thr Ser Lys Asn Ser Ser Leu Leu Ser Ile Asp Asn 
    50                  55                  60                  


Glu Glu Glu Met Lys Phe Leu Ala Ser Ile Leu Pro Ser Ser Trp Ile 
65                  70                  75                  80  


Gly Val Phe Arg Asn Ser Ser His His Pro Trp Val Thr Ile Asn Gly 
                85                  90                  95      


Leu Ala Phe Lys His Lys Ile Lys Asp Ser Asp Asn Ala Glu Leu Asn 
            100                 105                 110         


Cys Ala Val Leu Gln Val Asn Arg Leu Lys Ser Ala Gln Cys Gly Ser 
        115                 120                 125             


Ser Met Ile Tyr His Cys Lys His Lys Leu 
    130                 135             


<210>  785
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  785

Ile Pro Phe Leu Glu Gln Asn Asn Ser Ser Pro Asn Ala Arg Thr Gln 
1               5                   10                  15      


Lys Ala Arg His Cys Gly His Cys Pro Glu Glu Trp Ile Thr Tyr Ser 
            20                  25                  30          


Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg Arg Thr Trp Glu Glu Ser 
        35                  40                  45              


Leu Gln Ala Cys Ala Ser Lys Asn Ser Ser Ser Leu Leu Cys Ile Asp 
    50                  55                  60                  


Asn Glu Glu Glu Met Lys Phe Leu Ala Ser Ile Leu Pro Ser Ser Trp 
65                  70                  75                  80  


Ile Gly Val Phe Arg Asn Ser Ser His His Pro Trp Val Thr Ile Asn 
                85                  90                  95      


Gly Leu Ala Phe Lys His Glu Ile Lys Asp Ser Asp His Ala Glu Arg 
            100                 105                 110         


Asn Cys Ala Met Leu His Val Arg Gly Leu Ile Ser Asp Gln Cys Gly 
        115                 120                 125             


Ser Ser Arg Ile Ile Arg Arg Gly Phe Ile Met Leu Thr Arg Leu Val 
    130                 135                 140                 


Leu Asn Ser 
145         


<210>  786
<211>  148
<212>  PRT
<213>  Homo Sapiens

<400>  786

Lys Asn Ser Phe Thr Lys Leu Ser Ile Glu Pro Ala Phe Thr Pro Gly 
1               5                   10                  15      


Pro Asn Ile Glu Leu Gln Lys Asp Ser Asp Cys Cys Ser Cys Gln Glu 
            20                  25                  30          


Lys Trp Val Gly Tyr Arg Cys Asn Cys Tyr Phe Ile Ser Ser Glu Gln 
        35                  40                  45              


Lys Thr Trp Asn Glu Ser Arg His Leu Cys Ala Ser Gln Lys Ser Ser 
    50                  55                  60                  


Leu Leu Gln Leu Gln Asn Thr Asp Glu Leu Asp Phe Met Ser Ser Ser 
65                  70                  75                  80  


Gln Gln Phe Tyr Trp Ile Gly Leu Ser Tyr Ser Glu Glu His Thr Ala 
                85                  90                  95      


Trp Leu Trp Glu Asn Gly Ser Ala Leu Ser Gln Tyr Leu Phe Pro Ser 
            100                 105                 110         


Phe Glu Thr Phe Asn Thr Lys Asn Cys Ile Ala Tyr Asn Pro Asn Gly 
        115                 120                 125             


Asn Ala Leu Asp Glu Ser Cys Glu Asp Lys Asn Arg Tyr Ile Cys Lys 
    130                 135                 140                 


Gln Gln Leu Ile 
145             


<210>  787
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  787

Leu Leu Val Ser Gln Gly Val Leu Leu Lys Cys Gln Lys Gly Ser Cys 
1               5                   10                  15      


Ser Asn Ala Thr Gln Tyr Glu Asp Thr Gly Asp Leu Lys Val Asn Asn 
            20                  25                  30          


Gly Thr Arg Arg Asn Ile Ser Asn Lys Asp Leu Cys Ala Ser Arg Ser 
        35                  40                  45              


Ala Asp Gln Thr Val Leu Cys Gln Ser Glu Trp Leu Lys Tyr Gln Gly 
    50                  55                  60                  


Lys Cys Cys Tyr Trp Phe Ser Asn Glu Met Lys Ser Trp Ser Asp Ser 
65                  70                  75                  80  


Tyr Val Tyr Cys Leu Glu Arg Lys Ser His Leu Leu Ile Ile His Asp 
                85                  90                  95      


Gln Leu Glu Met Ala Phe Ile Gln Lys Asn Leu Arg Gln Leu Asn Tyr 
            100                 105                 110         


Val Trp Ile Gly Leu Asn Phe Thr Ser Leu Lys Met Thr Trp Thr Trp 
        115                 120                 125             


Val Asp Gly Ser Pro Ile Asp Ser Lys Ile Phe Phe Ile Lys Gly Pro 
    130                 135                 140                 


Ala Lys Glu Asn Ser Cys Ala Ala Ile Lys Glu Ser Lys Ile Phe Ser 
145                 150                 155                 160 


Glu Thr Cys Ser Ser Val Phe Lys Trp Ile Cys Gln Tyr 
                165                 170             


<210>  788
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  788

Asp Leu Lys Phe Trp His Lys Lys Met Asp Phe Ser Gln Asn Val Asn 
1               5                   10                  15      


Val Ser Ser Leu Ser Gly His Asn Tyr Leu Cys Pro Asn Asp Trp Leu 
            20                  25                  30          


Leu Asn Glu Gly Lys Cys Tyr Trp Phe Ser Thr Ser Phe Lys Thr Trp 
        35                  40                  45              


Lys Glu Ser Gln Arg Asp Cys Thr Gln Leu Gln Ala His Leu Leu Val 
    50                  55                  60                  


Ile Gln Asn Leu Asp Glu Leu Glu Phe Ile Gln Asn Ser Leu Lys Pro 
65                  70                  75                  80  


Gly His Phe Gly Trp Ile Gly Leu Tyr Val Thr Phe Gln Gly Asn Leu 
                85                  90                  95      


Trp Met Trp Ile Asp Glu His Phe Leu Val Pro Glu Leu Phe Ser Val 
            100                 105                 110         


Ile Gly Pro Thr Asp Asp Arg Ser Cys Ala Val Ile Thr Gly Asn Trp 
        115                 120                 125             


Val Tyr Ser Glu Asp Cys Ser Ser Thr Phe Lys Gly Ile Cys Gln Arg 
    130                 135                 140                 


Asp Ala Ile Leu Thr His Asn Gly Thr Ser Gly Val 
145                 150                 155     


<210>  789
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  789

Leu Cys Gln Gly Ser Asn Tyr Ser Thr Cys Ala Ser Cys Pro Ser Cys 
1               5                   10                  15      


Pro Asp Arg Trp Met Lys Tyr Gly Asn His Cys Tyr Tyr Phe Ser Val 
            20                  25                  30          


Glu Glu Lys Asp Trp Asn Ser Ser Leu Glu Phe Cys Leu Ala Arg Asp 
        35                  40                  45              


Ser His Leu Leu Val Ile Thr Asp Asn Gln Glu Met Ser Leu Leu Gln 
    50                  55                  60                  


Val Phe Leu Ser Glu Ala Phe Cys Trp Ile Gly Leu Arg Asn Asn Ser 
65                  70                  75                  80  


Gly Trp Arg Trp Glu Asp Gly Ser Pro Leu Asn Phe Ser Arg Ile Ser 
                85                  90                  95      


Ser Asn Ser Phe Val Gln Thr Cys Gly Ala Ile Asn Lys Asn Gly Leu 
            100                 105                 110         


Gln Ala Ser Ser Cys Glu Val Pro Leu His Trp Val Cys Lys Lys Cys 
        115                 120                 125             


Pro Phe Ala Asp Gln Ala Leu Phe 
    130                 135     


<210>  790
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  790

Ile Trp Ser Ala Val Phe Leu Asn Ser Leu Phe Asn Gln Glu Val Gln 
1               5                   10                  15      


Ile Pro Leu Thr Glu Ser Tyr Cys Gly Pro Cys Pro Lys Asn Trp Ile 
            20                  25                  30          


Cys Tyr Lys Asn Asn Cys Tyr Gln Phe Phe Asp Glu Ser Lys Asn Trp 
        35                  40                  45              


Tyr Glu Ser Gln Ala Ser Cys Met Ser Gln Asn Ala Ser Leu Leu Lys 
    50                  55                  60                  


Val Tyr Ser Lys Glu Asp Gln Asp Leu Leu Lys Leu Val Lys Ser Tyr 
65                  70                  75                  80  


His Trp Met Gly Leu Val His Ile Pro Thr Asn Gly Ser Trp Gln Trp 
                85                  90                  95      


Glu Asp Gly Ser Ile Leu Ser Pro Asn Leu Leu Thr Ile Ile Glu Met 
            100                 105                 110         


Gln Lys Gly Asp Cys Ala Leu Tyr Ala Ser Ser Phe Lys Gly Tyr Ile 
        115                 120                 125             


Glu Asn Cys Ser Thr Pro Asn Thr Tyr Ile Cys Met Gln Arg Thr Val 
    130                 135                 140                 


<210>  791
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  791

Gln Ala Pro Arg Gln Lys Gln Gly Ser Thr Gly Glu Glu Phe His Phe 
1               5                   10                  15      


Gln Thr Gly Gly Arg Asp Ser Cys Thr Met Arg Pro Ser Ser Leu Gly 
            20                  25                  30          


Gln Gly Ala Gly Glu Val Trp Leu Arg Val Asp Cys Arg Asn Thr Asp 
        35                  40                  45              


Gln Thr Tyr Trp Cys Glu Tyr Arg Gly Gln Pro Ser Met Cys Gln Ala 
    50                  55                  60                  


Phe Ala Ala Asp Pro Lys Pro Tyr Trp Asn Gln Ala Leu Gln Glu Leu 
65                  70                  75                  80  


Arg Arg Leu His His Ala Cys Gln Gly Ala Pro Val Leu Arg Pro Ser 
                85                  90                  95      


Val Cys Arg Glu Ala Gly Pro Gln Ala His Met Gln Gln Val Thr Ser 
            100                 105                 110         


Ser Leu Lys Gly Ser Pro Glu Pro Asn Gln Gln Pro Glu Ala Gly Thr 
        115                 120                 125             


Pro Ser Leu Arg Pro Lys Ala Thr Val Lys Leu Thr Glu Ala Thr Gln 
    130                 135                 140                 


Leu Gly Lys Asp Ser Met Glu Glu Leu Gly Lys Ala Lys Pro Thr Thr 
145                 150                 155                 160 


Arg Pro Thr Ala Lys Pro Thr Gln Pro Gly Pro Arg Pro Gly Gly Asn 
                165                 170                 175     


Glu Glu Ala Lys Lys Lys Ala Trp Glu His Cys Trp Lys Pro Phe Gln 
            180                 185                 190         


Ala Leu Cys Ala Phe Leu Ile Ser Phe Phe Arg Gly 
        195                 200                 


<210>  792
<211>  1101
<212>  PRT
<213>  Homo Sapiens

<400>  792

Ile Gln Ile Pro Glu Glu Tyr Glu Gly His His Val Met Glu Pro Pro 
1               5                   10                  15      


Val Ile Thr Glu Gln Ser Pro Arg Arg Leu Val Val Phe Pro Thr Asp 
            20                  25                  30          


Asp Ile Ser Leu Lys Cys Glu Ala Ser Gly Lys Pro Glu Val Gln Phe 
        35                  40                  45              


Arg Trp Thr Arg Asp Gly Val His Phe Lys Pro Lys Glu Glu Leu Gly 
    50                  55                  60                  


Val Thr Val Tyr Gln Ser Pro His Ser Gly Ser Phe Thr Ile Thr Gly 
65                  70                  75                  80  


Asn Asn Ser Asn Phe Ala Gln Arg Phe Gln Gly Ile Tyr Arg Cys Phe 
                85                  90                  95      


Ala Ser Asn Lys Leu Gly Thr Ala Met Ser His Glu Ile Arg Leu Met 
            100                 105                 110         


Ala Glu Gly Ala Pro Lys Trp Pro Lys Glu Thr Val Lys Pro Val Glu 
        115                 120                 125             


Val Glu Glu Gly Glu Ser Val Val Leu Pro Cys Asn Pro Pro Pro Ser 
    130                 135                 140                 


Ala Glu Pro Leu Arg Ile Tyr Trp Met Asn Ser Lys Ile Leu His Ile 
145                 150                 155                 160 


Lys Gln Asp Glu Arg Val Thr Met Gly Gln Asn Gly Asn Leu Tyr Phe 
                165                 170                 175     


Ala Asn Val Leu Thr Ser Asp Asn His Ser Asp Tyr Ile Cys His Ala 
            180                 185                 190         


His Phe Pro Gly Thr Arg Thr Ile Ile Gln Lys Glu Pro Ile Asp Leu 
        195                 200                 205             


Arg Val Lys Ala Thr Asn Ser Met Ile Asp Arg Lys Pro Arg Leu Leu 
    210                 215                 220                 


Phe Pro Thr Asn Ser Ser Ser His Leu Val Ala Leu Gln Gly Gln Pro 
225                 230                 235                 240 


Leu Val Leu Glu Cys Ile Ala Glu Gly Phe Pro Thr Pro Thr Ile Lys 
                245                 250                 255     


Trp Leu Arg Pro Ser Gly Pro Met Pro Ala Asp Arg Val Thr Tyr Gln 
            260                 265                 270         


Asn His Asn Lys Thr Leu Gln Leu Leu Lys Val Gly Glu Glu Asp Asp 
        275                 280                 285             


Gly Glu Tyr Arg Cys Leu Ala Glu Asn Ser Leu Gly Ser Ala Arg His 
    290                 295                 300                 


Ala Tyr Tyr Val Thr Val Glu Ala Ala Pro Tyr Trp Leu His Lys Pro 
305                 310                 315                 320 


Gln Ser His Leu Tyr Gly Pro Gly Glu Thr Ala Arg Leu Asp Cys Gln 
                325                 330                 335     


Val Gln Gly Arg Pro Gln Pro Glu Val Thr Trp Arg Ile Asn Gly Ile 
            340                 345                 350         


Pro Val Glu Glu Leu Ala Lys Asp Gln Lys Tyr Arg Ile Gln Arg Gly 
        355                 360                 365             


Ala Leu Ile Leu Ser Asn Val Gln Pro Ser Asp Thr Met Val Thr Gln 
    370                 375                 380                 


Cys Glu Ala Arg Asn Arg His Gly Leu Leu Leu Ala Asn Ala Tyr Ile 
385                 390                 395                 400 


Tyr Val Val Gln Leu Pro Ala Lys Ile Leu Thr Ala Asp Asn Gln Thr 
                405                 410                 415     


Tyr Met Ala Val Gln Gly Ser Thr Ala Tyr Leu Leu Cys Lys Ala Phe 
            420                 425                 430         


Gly Ala Pro Val Pro Ser Val Gln Trp Leu Asp Glu Asp Gly Thr Thr 
        435                 440                 445             


Val Leu Gln Asp Glu Arg Phe Phe Pro Tyr Ala Asn Gly Thr Leu Gly 
    450                 455                 460                 


Ile Arg Asp Leu Gln Ala Asn Asp Thr Gly Arg Tyr Phe Cys Leu Ala 
465                 470                 475                 480 


Ala Asn Asp Gln Asn Asn Val Thr Ile Met Ala Asn Leu Lys Val Lys 
                485                 490                 495     


Asp Ala Thr Gln Ile Thr Gln Gly Pro Arg Ser Thr Ile Glu Lys Lys 
            500                 505                 510         


Gly Ser Arg Val Thr Phe Thr Cys Gln Ala Ser Phe Asp Pro Ser Leu 
        515                 520                 525             


Gln Pro Ser Ile Thr Trp Arg Gly Asp Gly Arg Asp Leu Gln Glu Leu 
    530                 535                 540                 


Gly Asp Ser Asp Lys Tyr Phe Ile Glu Asp Gly Arg Leu Val Ile His 
545                 550                 555                 560 


Ser Leu Asp Tyr Ser Asp Gln Gly Asn Tyr Ser Cys Val Ala Ser Thr 
                565                 570                 575     


Glu Leu Asp Val Val Glu Ser Arg Ala Gln Leu Leu Val Val Gly Ser 
            580                 585                 590         


Pro Gly Pro Val Pro Arg Leu Val Leu Ser Asp Leu His Leu Leu Thr 
        595                 600                 605             


Gln Ser Gln Val Arg Val Ser Trp Ser Pro Ala Glu Asp His Asn Ala 
    610                 615                 620                 


Pro Ile Glu Lys Tyr Asp Ile Glu Phe Glu Asp Lys Glu Met Ala Pro 
625                 630                 635                 640 


Glu Lys Trp Tyr Ser Leu Gly Lys Val Pro Gly Asn Gln Thr Ser Thr 
                645                 650                 655     


Thr Leu Lys Leu Ser Pro Tyr Val His Tyr Thr Phe Arg Val Thr Ala 
            660                 665                 670         


Ile Asn Lys Tyr Gly Pro Gly Glu Pro Ser Pro Val Ser Glu Thr Val 
        675                 680                 685             


Val Thr Pro Glu Ala Ala Pro Glu Lys Asn Pro Val Asp Val Lys Gly 
    690                 695                 700                 


Glu Gly Asn Glu Thr Thr Asn Met Val Ile Thr Trp Lys Pro Leu Arg 
705                 710                 715                 720 


Trp Met Asp Trp Asn Ala Pro Gln Val Gln Tyr Arg Val Gln Trp Arg 
                725                 730                 735     


Pro Gln Gly Thr Arg Gly Pro Trp Gln Glu Gln Ile Val Ser Asp Pro 
            740                 745                 750         


Phe Leu Val Val Ser Asn Thr Ser Thr Phe Val Pro Tyr Glu Ile Lys 
        755                 760                 765             


Val Gln Ala Val Asn Ser Gln Gly Lys Gly Pro Glu Pro Gln Val Thr 
    770                 775                 780                 


Ile Gly Tyr Ser Gly Glu Asp Tyr Pro Gln Ala Ile Pro Glu Leu Glu 
785                 790                 795                 800 


Gly Ile Glu Ile Leu Asn Ser Ser Ala Val Leu Val Lys Trp Arg Pro 
                805                 810                 815     


Val Asp Leu Ala Gln Val Lys Gly His Leu Arg Gly Tyr Asn Val Thr 
            820                 825                 830         


Tyr Trp Arg Glu Gly Ser Gln Arg Lys His Ser Lys Arg His Ile His 
        835                 840                 845             


Lys Asp His Val Val Val Pro Ala Asn Thr Thr Ser Val Ile Leu Ser 
    850                 855                 860                 


Gly Leu Arg Pro Tyr Ser Ser Tyr His Leu Glu Val Gln Ala Phe Asn 
865                 870                 875                 880 


Gly Arg Gly Ser Gly Pro Ala Ser Glu Phe Thr Phe Ser Thr Pro Glu 
                885                 890                 895     


Gly Val Pro Gly His Pro Glu Ala Leu His Leu Glu Cys Gln Ser Asn 
            900                 905                 910         


Thr Ser Leu Leu Leu Arg Trp Gln Pro Pro Leu Ser His Asn Gly Val 
        915                 920                 925             


Leu Thr Gly Tyr Val Leu Ser Tyr His Pro Leu Asp Glu Gly Gly Lys 
    930                 935                 940                 


Gly Gln Leu Ser Phe Asn Leu Arg Asp Pro Glu Leu Arg Thr His Asn 
945                 950                 955                 960 


Leu Thr Asp Leu Ser Pro His Leu Arg Tyr Arg Phe Gln Leu Gln Ala 
                965                 970                 975     


Thr Thr Lys Glu Gly Pro Gly Glu Ala Ile Val Arg Glu Gly Gly Thr 
            980                 985                 990         


Met Ala Leu Ser Gly Ile Ser Asp  Phe Gly Asn Ile Ser  Ala Thr Ala 
        995                 1000                 1005             


Gly Glu  Asn Tyr Ser Val Val  Ser Trp Val Pro Lys  Glu Gly Gln 
    1010                 1015                 1020             


Cys Asn  Phe Arg Phe His Ile  Leu Phe Lys Ala Leu  Gly Glu Glu 
    1025                 1030                 1035             


Lys Gly  Gly Ala Ser Leu Ser  Pro Gln Tyr Val Ser  Tyr Asn Gln 
    1040                 1045                 1050             


Ser Ser  Tyr Thr Gln Trp Asp  Leu Gln Pro Asp Thr  Asp Tyr Glu 
    1055                 1060                 1065             


Ile His  Leu Phe Lys Glu Arg  Met Phe Arg His Gln  Met Ala Val 
    1070                 1075                 1080             


Lys Thr  Asn Gly Thr Gly Arg  Val Arg Leu Pro Pro  Ala Gly Phe 
    1085                 1090                 1095             


Ala Thr  Glu 
    1100     


<210>  793
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  793

Val Pro Val Val Trp Ala Gln Glu Gly Ala Pro Ala Gln Leu Pro Cys 
1               5                   10                  15      


Ser Pro Thr Ile Pro Leu Gln Asp Leu Ser Leu Leu Arg Arg Ala Gly 
            20                  25                  30          


Val Thr Trp Gln His Gln Pro Asp Ser Gly Pro Pro Ala Ala Ala Pro 
        35                  40                  45              


Gly His Pro Leu Ala Pro Gly Pro His Pro Ala Ala Pro Ser Ser Trp 
    50                  55                  60                  


Gly Pro Arg Pro Arg Arg Tyr Thr Val Leu Ser Val Gly Pro Gly Gly 
65                  70                  75                  80  


Leu Arg Ser Gly Arg Leu Pro Leu Gln Pro Arg Val Gln Leu Asp Glu 
                85                  90                  95      


Arg Gly Arg Gln Arg Gly Asp Phe Ser Leu Trp Leu Arg Pro Ala Arg 
            100                 105                 110         


Arg Ala Asp Ala Gly Glu Tyr Arg Ala Ala Val His Leu Arg Asp Arg 
        115                 120                 125             


Ala Leu Ser Cys Arg Leu Arg Leu Arg Leu Gly Gln Ala Ser Met Thr 
    130                 135                 140                 


Ala Ser Pro Pro Gly Ser Leu Arg Ala Ser Asp Trp Val Ile Leu Asn 
145                 150                 155                 160 


Cys Ser Phe Ser Arg Pro Asp Arg Pro Ala Ser Val His Trp Phe Arg 
                165                 170                 175     


Asn Arg Gly Gln Gly Arg Val Pro Val Arg Glu Ser Pro His His His 
            180                 185                 190         


Leu Ala Glu Ser Phe Leu Phe Leu Pro Gln Val Ser Pro Met Asp Ser 
        195                 200                 205             


Gly Pro Trp Gly Cys Ile Leu Thr Tyr Arg Asp Gly Phe Asn Val Ser 
    210                 215                 220                 


Ile Met Tyr Asn Leu Thr Val Leu Gly Leu Glu Pro Pro Thr Pro Leu 
225                 230                 235                 240 


Thr Val Tyr Ala Gly Ala Gly Ser Arg Val Gly Leu Pro Cys Arg Leu 
                245                 250                 255     


Pro Ala Gly Val Gly Thr Arg Ser Phe Leu Thr Ala Lys Trp Thr Pro 
            260                 265                 270         


Pro Gly Gly Gly Pro Asp Leu Leu Val Thr Gly Asp Asn Gly Asp Phe 
        275                 280                 285             


Thr Leu Arg Leu Glu Asp Val Ser Gln Ala Gln Ala Gly Thr Tyr Thr 
    290                 295                 300                 


Cys His Ile His Leu Gln Glu Gln Gln Leu Asn Ala Thr Val Thr Leu 
305                 310                 315                 320 


Ala Ile Ile Thr Gly Gln Pro Gln Val Gly Lys Glu 
                325                 330         


<210>  794
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  794

Gln Glu Glu Asp Leu Pro Arg Pro Ser Ile Ser Ala Glu Pro Gly Thr 
1               5                   10                  15      


Val Ile Pro Leu Gly Ser His Val Thr Phe Val Cys Arg Gly Pro Val 
            20                  25                  30          


Gly Val Gln Thr Phe Arg Leu Glu Arg Glu Ser Arg Ser Thr Tyr Asn 
        35                  40                  45              


Asp Thr Glu Asp Val Ser Gln Ala Ser Pro Ser Glu Ser Glu Ala Arg 
    50                  55                  60                  


Phe Arg Ile Asp Ser Val Ser Glu Gly Asn Ala Gly Pro Tyr Arg Cys 
65                  70                  75                  80  


Ile Tyr Tyr Lys Pro Pro Lys Trp Ser Glu Gln Ser Asp Tyr Leu Glu 
                85                  90                  95      


Leu Leu Val Lys Glu Thr Ser Gly Gly Pro Asp Ser Pro Asp Thr Glu 
            100                 105                 110         


Pro Gly Ser Ser Ala Gly Pro Thr Gln Arg Pro Ser Asp Asn Ser His 
        115                 120                 125             


Asn Glu His Ala Pro Ala Ser Gln Gly Leu Lys Ala Glu His Leu Tyr 
    130                 135                 140                 


<210>  795
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  795

Gln Glu Gly Ala Leu Pro Arg Pro Ser Ile Ser Ala Glu Pro Gly Thr 
1               5                   10                  15      


Val Ile Ser Pro Gly Ser His Val Thr Phe Met Cys Arg Gly Pro Val 
            20                  25                  30          


Gly Val Gln Thr Phe Arg Leu Glu Arg Glu Asp Arg Ala Lys Tyr Lys 
        35                  40                  45              


Asp Ser Tyr Asn Val Phe Arg Leu Gly Pro Ser Glu Ser Glu Ala Arg 
    50                  55                  60                  


Phe His Ile Asp Ser Val Ser Glu Gly Asn Ala Gly Leu Tyr Arg Cys 
65                  70                  75                  80  


Leu Tyr Tyr Lys Pro Pro Gly Trp Ser Glu His Ser Asp Phe Leu Glu 
                85                  90                  95      


Leu Leu Val Lys Glu Ser Ser Gly Gly Pro Asp Ser Pro Asp Thr Glu 
            100                 105                 110         


Pro Gly Ser Ser Ala Gly Thr Val Pro Gly Thr Glu Ala Ser Gly Phe 
        115                 120                 125             


Asp Ala Pro 
    130     


<210>  796
<211>  2573
<212>  PRT
<213>  Homo Sapiens

<400>  796

Cys Phe Cys Phe Gly Val Ser Asp Val Cys Ser Ser Leu Ser Trp Pro 
1               5                   10                  15      


Val Gly Gln Val Asn Ser Met Ser Gly Trp Leu Val Thr Asp Leu Ile 
            20                  25                  30          


Ser Pro Arg Lys Ile Pro Ser Gln Gln Asp Ala Leu Gly Gly Arg His 
        35                  40                  45              


Gln Val Ser Ile Asn Asn Thr Ala Val Met Gln Arg Leu Ala Pro Lys 
    50                  55                  60                  


Tyr Tyr Trp Ala Ala Pro Glu Ala Tyr Leu Gly Asn Lys Leu Thr Ala 
65                  70                  75                  80  


Phe Gly Gly Phe Leu Lys Tyr Thr Val Ser Tyr Asp Ile Pro Val Glu 
                85                  90                  95      


Thr Val Asp Ser Asn Leu Met Ser His Ala Asp Val Ile Ile Lys Gly 
            100                 105                 110         


Asn Gly Leu Thr Leu Ser Thr Gln Ala Glu Gly Leu Ser Leu Gln Pro 
        115                 120                 125             


Tyr Glu Glu Tyr Leu Asn Val Val Arg Leu Val Pro Glu Asn Phe Gln 
    130                 135                 140                 


Asp Phe His Ser Lys Arg Gln Ile Asp Arg Asp Gln Leu Met Thr Val 
145                 150                 155                 160 


Ile Ala Asn Val Thr His Leu Leu Ile Arg Ala Asn Tyr Asn Ser Ala 
                165                 170                 175     


Lys Met Ala Leu Tyr Arg Leu Glu Ser Val Ser Leu Asp Ile Ala Ser 
            180                 185                 190         


Ser Asn Ala Ile Asp Leu Val Val Ala Ala Asp Val Glu His Cys Glu 
        195                 200                 205             


Cys Pro Gln Gly Tyr Thr Gly Thr Ser Cys Glu Ser Cys Leu Ser Gly 
    210                 215                 220                 


Tyr Tyr Arg Val Asp Gly Ile Leu Phe Gly Gly Ile Cys Gln Pro Cys 
225                 230                 235                 240 


Glu Cys His Gly His Ala Ala Glu Cys Asn Val His Gly Val Cys Ile 
                245                 250                 255     


Ala Cys Ala His Asn Thr Thr Gly Val His Cys Glu Gln Cys Leu Pro 
            260                 265                 270         


Gly Phe Tyr Gly Glu Pro Ser Arg Gly Thr Pro Gly Asp Cys Gln Pro 
        275                 280                 285             


Cys Ala Cys Pro Leu Thr Ile Ala Ser Asn Asn Phe Ser Pro Thr Cys 
    290                 295                 300                 


His Leu Asn Asp Gly Asp Glu Val Val Cys Asp Trp Cys Ala Pro Gly 
305                 310                 315                 320 


Tyr Ser Gly Ala Trp Cys Glu Arg Cys Ala Asp Gly Tyr Tyr Gly Asn 
                325                 330                 335     


Pro Thr Val Pro Gly Glu Ser Cys Val Pro Cys Asp Cys Ser Gly Asn 
            340                 345                 350         


Val Asp Pro Ser Glu Ala Gly His Cys Asp Ser Val Thr Gly Glu Cys 
        355                 360                 365             


Leu Lys Cys Leu Gly Asn Thr Asp Gly Ala His Cys Glu Arg Cys Ala 
    370                 375                 380                 


Asp Gly Phe Tyr Gly Asp Ala Val Thr Ala Lys Asn Cys Arg Ala Cys 
385                 390                 395                 400 


Glu Cys His Val Lys Gly Ser His Ser Ala Val Cys His Leu Glu Thr 
                405                 410                 415     


Gly Leu Cys Asp Cys Lys Pro Asn Val Thr Gly Gln Gln Cys Asp Gln 
            420                 425                 430         


Cys Leu His Gly Tyr Tyr Gly Leu Asp Ser Gly His Gly Cys Arg Pro 
        435                 440                 445             


Cys Asn Cys Ser Val Ala Gly Ser Val Ser Asp Gly Cys Thr Asp Glu 
    450                 455                 460                 


Gly Gln Cys His Cys Val Pro Gly Val Ala Gly Lys Arg Cys Asp Arg 
465                 470                 475                 480 


Cys Ala His Gly Phe Tyr Ala Tyr Gln Asp Gly Ser Cys Thr Pro Cys 
                485                 490                 495     


Asp Cys Pro His Thr Gln Asn Thr Cys Asp Pro Glu Thr Gly Glu Cys 
            500                 505                 510         


Val Cys Pro Pro His Thr Gln Gly Val Lys Cys Glu Glu Cys Glu Asp 
        515                 520                 525             


Gly His Trp Gly Tyr Asp Ala Glu Val Gly Cys Gln Ala Cys Asn Cys 
    530                 535                 540                 


Ser Leu Val Gly Ser Thr His His Arg Cys Asp Val Val Thr Gly His 
545                 550                 555                 560 


Cys Gln Cys Lys Ser Lys Phe Gly Gly Arg Ala Cys Asp Gln Cys Ser 
                565                 570                 575     


Leu Gly Tyr Arg Asp Phe Pro Asp Cys Val Pro Cys Asp Cys Asp Leu 
            580                 585                 590         


Arg Gly Thr Ser Gly Asp Ala Cys Asn Leu Glu Gln Gly Leu Cys Gly 
        595                 600                 605             


Cys Val Glu Glu Thr Gly Ala Cys Pro Cys Lys Glu Asn Val Phe Gly 
    610                 615                 620                 


Pro Gln Cys Asn Glu Cys Arg Glu Gly Thr Phe Ala Leu Arg Ala Asp 
625                 630                 635                 640 


Asn Pro Leu Gly Cys Ser Pro Cys Phe Cys Ser Gly Leu Ser His Leu 
                645                 650                 655     


Cys Ser Glu Leu Glu Asp Tyr Val Arg Thr Pro Val Thr Leu Gly Ser 
            660                 665                 670         


Asp Gln Pro Leu Leu Arg Val Val Ser Gln Ser Asn Leu Arg Gly Thr 
        675                 680                 685             


Thr Glu Gly Val Tyr Tyr Gln Ala Pro Asp Phe Leu Leu Asp Ala Ala 
    690                 695                 700                 


Thr Val Arg Gln His Ile Arg Ala Glu Pro Phe Tyr Trp Arg Leu Pro 
705                 710                 715                 720 


Gln Gln Phe Gln Gly Asp Gln Leu Met Ala Tyr Gly Gly Lys Leu Lys 
                725                 730                 735     


Tyr Ser Val Ala Phe Tyr Ser Leu Asp Gly Val Gly Thr Ser Asn Phe 
            740                 745                 750         


Glu Pro Gln Val Leu Ile Lys Gly Gly Arg Ile Arg Lys Gln Val Ile 
        755                 760                 765             


Tyr Met Asp Ala Pro Ala Pro Glu Asn Gly Val Arg Gln Glu Gln Glu 
    770                 775                 780                 


Val Ala Met Arg Glu Asn Phe Trp Lys Tyr Phe Asn Ser Val Ser Glu 
785                 790                 795                 800 


Lys Pro Val Thr Arg Glu Asp Phe Met Ser Val Leu Ser Asp Ile Glu 
                805                 810                 815     


Tyr Ile Leu Ile Lys Ala Ser Tyr Gly Gln Gly Leu Gln Gln Ser Arg 
            820                 825                 830         


Ile Ser Asp Ile Ser Met Glu Val Gly Arg Lys Ala Glu Lys Leu His 
        835                 840                 845             


Pro Glu Glu Glu Val Ala Ser Leu Leu Glu Asn Cys Val Cys Pro Pro 
    850                 855                 860                 


Gly Thr Val Gly Phe Ser Cys Gln Asp Cys Ala Pro Gly Tyr His Arg 
865                 870                 875                 880 


Gly Lys Leu Pro Ala Gly Ser Asp Arg Gly Pro Arg Pro Leu Val Ala 
                885                 890                 895     


Pro Cys Val Pro Cys Ser Cys Asn Asn His Ser Asp Thr Cys Asp Pro 
            900                 905                 910         


Asn Thr Gly Lys Cys Leu Asn Cys Gly Asp Asn Thr Ala Gly Asp His 
        915                 920                 925             


Cys Asp Val Cys Thr Ser Gly Tyr Tyr Gly Lys Val Thr Gly Ser Ala 
    930                 935                 940                 


Ser Asp Cys Ala Leu Cys Ala Cys Pro His Ser Pro Pro Ala Ser Phe 
945                 950                 955                 960 


Ser Pro Thr Cys Val Leu Glu Gly Asp His Asp Phe Arg Cys Asp Ala 
                965                 970                 975     


Cys Leu Leu Gly Tyr Glu Gly Lys His Cys Glu Arg Cys Ser Ser Ser 
            980                 985                 990         


Tyr Tyr Gly Asn Pro Gln Thr Pro  Gly Gly Ser Cys Gln  Lys Cys Asp 
        995                 1000                 1005             


Cys Asn  Pro His Gly Ser Val  His Gly Asp Cys Asp  Arg Thr Ser 
    1010                 1015                 1020             


Gly Gln  Cys Val Cys Arg Leu  Gly Ala Ser Gly Leu  Arg Cys Asp 
    1025                 1030                 1035             


Glu Cys  Glu Pro Arg His Ile  Leu Met Glu Thr Asp  Cys Val Ser 
    1040                 1045                 1050             


Cys Asp  Asp Glu Cys Val Gly  Val Leu Leu Asn Asp  Leu Asp Glu 
    1055                 1060                 1065             


Ile Gly  Asp Ala Val Leu Ser  Leu Asn Leu Ala Gly  Ile Ile Pro 
    1070                 1075                 1080             


Val Pro  Tyr Gly Ile Leu Ser  Asn Leu Glu Asn Thr  Thr Lys Tyr 
    1085                 1090                 1095             


Leu Gln  Glu Ser Leu Leu Lys  Glu Asn Met Gln Lys  Asp Leu Gly 
    1100                 1105                 1110             


Lys Ile  Lys Leu Glu Gly Val  Ala Glu Glu Thr Asp  Asn Leu Gln 
    1115                 1120                 1125             


Lys Lys  Leu Thr Arg Met Leu  Ala Ser Thr Gln Lys  Val Asn Arg 
    1130                 1135                 1140             


Ala Thr  Glu Arg Ile Phe Lys  Glu Ser Gln Asp Leu  Ala Ile Ala 
    1145                 1150                 1155             


Ile Glu  Arg Leu Gln Met Ser  Ile Thr Glu Ile Met  Glu Lys Thr 
    1160                 1165                 1170             


Thr Leu  Asn Gln Thr Leu Asp  Glu Asp Phe Leu Leu  Pro Asn Ser 
    1175                 1180                 1185             


Thr Leu  Gln Asn Met Gln Gln  Asn Gly Thr Ser Leu  Leu Glu Ile 
    1190                 1195                 1200             


Met Gln  Ile Arg Asp Phe Thr  Gln Leu His Gln Asn  Ala Thr Leu 
    1205                 1210                 1215             


Glu Leu  Lys Ala Ala Glu Asp  Leu Leu Ser Gln Ile  Gln Glu Asn 
    1220                 1225                 1230             


Tyr Gln  Lys Pro Leu Glu Glu  Leu Glu Val Leu Lys  Glu Ala Ala 
    1235                 1240                 1245             


Ser His  Val Leu Ser Lys His  Asn Asn Glu Leu Lys  Ala Ala Glu 
    1250                 1255                 1260             


Ala Leu  Val Arg Glu Ala Glu  Ala Lys Met Gln Glu  Ser Asn His 
    1265                 1270                 1275             


Leu Leu  Leu Met Val Asn Ala  Asn Leu Arg Glu Phe  Ser Asp Lys 
    1280                 1285                 1290             


Lys Leu  His Val Gln Glu Glu  Gln Asn Leu Thr Ser  Glu Leu Ile 
    1295                 1300                 1305             


Val Gln  Gly Arg Gly Leu Ile  Asp Ala Ala Ala Ala  Gln Thr Asp 
    1310                 1315                 1320             


Ala Val  Gln Asp Ala Leu Glu  His Leu Glu Asp His  Gln Asp Lys 
    1325                 1330                 1335             


Leu Leu  Leu Trp Ser Ala Lys  Ile Arg His His Ile  Asp Asp Leu 
    1340                 1345                 1350             


Val Met  His Met Ser Gln Arg  Asn Ala Val Asp Leu  Val Tyr Arg 
    1355                 1360                 1365             


Ala Glu  Asp His Ala Ala Glu  Phe Gln Arg Leu Ala  Asp Val Leu 
    1370                 1375                 1380             


Tyr Ser  Gly Leu Glu Asn Ile  Arg Asn Val Ser Leu  Asn Ala Thr 
    1385                 1390                 1395             


Ser Ala  Ala Tyr Val His Tyr  Asn Ile Gln Ser Leu  Ile Glu Glu 
    1400                 1405                 1410             


Ser Glu  Glu Leu Ala Arg Asp  Ala His Arg Thr Val  Thr Glu Thr 
    1415                 1420                 1425             


Ser Leu  Leu Ser Glu Ser Leu  Val Ser Asn Gly Lys  Ala Ala Val 
    1430                 1435                 1440             


Gln Arg  Ser Ser Arg Phe Leu  Lys Glu Gly Asn Asn  Leu Ser Arg 
    1445                 1450                 1455             


Lys Leu  Pro Gly Ile Ala Leu  Glu Leu Ser Glu Leu  Arg Asn Lys 
    1460                 1465                 1470             


Thr Asn  Arg Phe Gln Glu Asn  Ala Val Glu Ile Thr  Arg Gln Thr 
    1475                 1480                 1485             


Asn Glu  Ser Leu Leu Ile Leu  Arg Ala Ile Pro Lys  Gly Ile Arg 
    1490                 1495                 1500             


Asp Lys  Gly Ala Lys Thr Lys  Glu Leu Ala Thr Ser  Ala Ser Gln 
    1505                 1510                 1515             


Ser Ala  Val Ser Thr Leu Arg  Asp Val Ala Gly Leu  Ser Gln Glu 
    1520                 1525                 1530             


Leu Leu  Asn Thr Ser Ala Ser  Leu Ser Arg Val Asn  Thr Thr Leu 
    1535                 1540                 1545             


Arg Glu  Thr His Gln Leu Leu  Gln Asp Ser Thr Met  Ala Thr Leu 
    1550                 1555                 1560             


Leu Ala  Gly Arg Lys Val Lys  Asp Val Glu Thr Gln  Ala Asn Leu 
    1565                 1570                 1575             


Leu Phe  Asp Arg Leu Lys Pro  Leu Lys Met Leu Glu  Glu Asn Leu 
    1580                 1585                 1590             


Ser Arg  Asn Leu Ser Glu Ile  Lys Leu Leu Ile Ser  Gln Ala Arg 
    1595                 1600                 1605             


Lys Gln  Ala Ala Ser Ile Lys  Val Ala Val Ser Ala  Asp Arg Asp 
    1610                 1615                 1620             


Cys Ile  Arg Ala Tyr Gln Pro  Gln Ile Ser Ser Thr  Asn Tyr Asn 
    1625                 1630                 1635             


Thr Leu  Thr Leu Asn Val Lys  Thr Gln Glu Pro Asp  Asn Leu Leu 
    1640                 1645                 1650             


Phe Tyr  Leu Gly Ser Ser Thr  Ala Ser Asp Phe Leu  Ala Val Glu 
    1655                 1660                 1665             


Met Arg  Arg Gly Arg Val Ala  Phe Leu Trp Asp Leu  Gly Ser Gly 
    1670                 1675                 1680             


Ser Thr  Arg Leu Glu Phe Pro  Asp Phe Pro Ile Asp  Asp Asn Arg 
    1685                 1690                 1695             


Trp His  Ser Ile His Val Ala  Arg Phe Gly Asn Ile  Gly Ser Leu 
    1700                 1705                 1710             


Ser Val  Lys Glu Met Ser Ser  Asn Gln Lys Ser Pro  Thr Lys Thr 
    1715                 1720                 1725             


Ser Lys  Ser Pro Gly Thr Ala  Asn Val Leu Asp Val  Asn Asn Ser 
    1730                 1735                 1740             


Thr Leu  Met Phe Val Gly Gly  Leu Gly Gly Gln Ile  Lys Lys Ser 
    1745                 1750                 1755             


Pro Ala  Val Lys Val Thr His  Phe Lys Gly Cys Leu  Gly Glu Ala 
    1760                 1765                 1770             


Phe Leu  Asn Gly Lys Ser Ile  Gly Leu Trp Asn Tyr  Ile Glu Arg 
    1775                 1780                 1785             


Glu Gly  Lys Cys Arg Gly Cys  Phe Gly Ser Ser Gln  Asn Glu Asp 
    1790                 1795                 1800             


Pro Ser  Phe His Phe Asp Gly  Ser Gly Tyr Ser Val  Val Glu Lys 
    1805                 1810                 1815             


Ser Leu  Pro Ala Thr Val Thr  Gln Ile Ile Met Leu  Phe Asn Thr 
    1820                 1825                 1830             


Phe Ser  Pro Asn Gly Leu Leu  Leu Tyr Leu Gly Ser  Tyr Gly Thr 
    1835                 1840                 1845             


Lys Asp  Phe Leu Ser Ile Glu  Leu Phe Arg Gly Arg  Val Lys Val 
    1850                 1855                 1860             


Met Thr  Asp Leu Gly Ser Gly  Pro Ile Thr Leu Leu  Thr Asp Arg 
    1865                 1870                 1875             


Arg Tyr  Asn Asn Gly Thr Trp  Tyr Lys Ile Ala Phe  Gln Arg Asn 
    1880                 1885                 1890             


Arg Lys  Gln Gly Val Leu Ala  Val Ile Asp Ala Tyr  Asn Thr Ser 
    1895                 1900                 1905             


Asn Lys  Glu Thr Lys Gln Gly  Glu Thr Pro Gly Ala  Ser Ser Asp 
    1910                 1915                 1920             


Leu Asn  Arg Leu Asp Lys Asp  Pro Ile Tyr Val Gly  Gly Leu Pro 
    1925                 1930                 1935             


Arg Ser  Arg Val Val Arg Arg  Gly Val Thr Thr Lys  Ser Phe Val 
    1940                 1945                 1950             


Gly Cys  Ile Lys Asn Leu Glu  Ile Ser Arg Ser Thr  Phe Asp Leu 
    1955                 1960                 1965             


Leu Arg  Asn Ser Tyr Gly Val  Arg Lys Gly Cys Leu  Leu Glu Pro 
    1970                 1975                 1980             


Ile Arg  Ser Val Ser Phe Leu  Lys Gly Gly Tyr Ile  Glu Leu Pro 
    1985                 1990                 1995             


Pro Lys  Ser Leu Ser Pro Glu  Ser Glu Trp Leu Val  Thr Phe Ala 
    2000                 2005                 2010             


Thr Thr  Asn Ser Ser Gly Ile  Ile Leu Ala Ala Leu  Gly Gly Asp 
    2015                 2020                 2025             


Val Glu  Lys Arg Gly Asp Arg  Glu Glu Ala His Val  Pro Phe Phe 
    2030                 2035                 2040             


Ser Val  Met Leu Ile Gly Gly  Asn Ile Glu Val His  Val Asn Pro 
    2045                 2050                 2055             


Gly Asp  Gly Thr Gly Leu Arg  Lys Ala Leu Leu His  Ala Pro Thr 
    2060                 2065                 2070             


Gly Thr  Cys Ser Asp Gly Gln  Ala His Ser Ile Ser  Leu Val Arg 
    2075                 2080                 2085             


Asn Arg  Arg Ile Ile Thr Val  Gln Leu Asp Glu Asn  Asn Pro Val 
    2090                 2095                 2100             


Glu Met  Lys Leu Gly Thr Leu  Val Glu Ser Arg Thr  Ile Asn Val 
    2105                 2110                 2115             


Ser Asn  Leu Tyr Val Gly Gly  Ile Pro Glu Gly Glu  Gly Thr Ser 
    2120                 2125                 2130             


Leu Leu  Thr Met Arg Arg Ser  Phe His Gly Cys Ile  Lys Asn Leu 
    2135                 2140                 2145             


Ile Phe  Asn Leu Glu Leu Leu  Asp Phe Asn Ser Ala  Val Gly His 
    2150                 2155                 2160             


Glu Gln  Val Asp Leu Asp Thr  Cys Trp Leu Ser Glu  Arg Pro Lys 
    2165                 2170                 2175             


Leu Ala  Pro Asp Ala Glu Asp  Ser Lys Leu Leu Pro  Glu Pro Arg 
    2180                 2185                 2190             


Ala Phe  Pro Glu Gln Cys Val  Val Asp Ala Ala Leu  Glu Tyr Val 
    2195                 2200                 2205             


Pro Gly  Ala His Gln Phe Gly  Leu Thr Gln Asn Ser  His Phe Ile 
    2210                 2215                 2220             


Leu Pro  Phe Asn Gln Ser Ala  Val Arg Lys Lys Leu  Ser Val Glu 
    2225                 2230                 2235             


Leu Ser  Ile Arg Thr Phe Ala  Ser Ser Gly Leu Ile  Tyr Tyr Met 
    2240                 2245                 2250             


Ala His  Gln Asn Gln Ala Asp  Tyr Ala Val Leu Gln  Leu His Gly 
    2255                 2260                 2265             


Gly Arg  Leu His Phe Met Phe  Asp Leu Gly Lys Gly  Arg Thr Lys 
    2270                 2275                 2280             


Val Ser  His Pro Ala Leu Leu  Ser Asp Gly Lys Trp  His Thr Val 
    2285                 2290                 2295             


Lys Thr  Asp Tyr Val Lys Arg  Lys Gly Phe Ile Thr  Val Asp Gly 
    2300                 2305                 2310             


Arg Glu  Ser Pro Met Val Thr  Val Val Gly Asp Gly  Thr Met Leu 
    2315                 2320                 2325             


Asp Val  Glu Gly Leu Phe Tyr  Leu Gly Gly Leu Pro  Ser Gln Tyr 
    2330                 2335                 2340             


Gln Ala  Arg Lys Ile Gly Asn  Ile Thr His Ser Ile  Pro Ala Cys 
    2345                 2350                 2355             


Ile Gly  Asp Val Thr Val Asn  Ser Lys Gln Leu Asp  Lys Asp Ser 
    2360                 2365                 2370             


Pro Val  Ser Ala Phe Thr Val  Asn Arg Cys Tyr Ala  Val Ala Gln 
    2375                 2380                 2385             


Glu Gly  Thr Tyr Phe Asp Gly  Ser Gly Tyr Ala Ala  Leu Val Lys 
    2390                 2395                 2400             


Glu Gly  Tyr Lys Val Gln Ser  Asp Val Asn Ile Thr  Leu Glu Phe 
    2405                 2410                 2415             


Arg Thr  Ser Ser Gln Asn Gly  Val Leu Leu Gly Ile  Ser Thr Ala 
    2420                 2425                 2430             


Lys Val  Asp Ala Ile Gly Leu  Glu Leu Val Asp Gly  Lys Val Leu 
    2435                 2440                 2445             


Phe His  Val Asn Asn Gly Ala  Gly Arg Ile Thr Ala  Ala Tyr Glu 
    2450                 2455                 2460             


Pro Lys  Thr Ala Thr Val Leu  Cys Asp Gly Lys Trp  His Thr Leu 
    2465                 2470                 2475             


Gln Ala  Asn Lys Ser Lys His  Arg Ile Thr Leu Ile  Val Asp Gly 
    2480                 2485                 2490             


Asn Ala  Val Gly Ala Glu Ser  Pro His Thr Gln Ser  Thr Ser Val 
    2495                 2500                 2505             


Asp Thr  Asn Asn Pro Ile Tyr  Val Gly Gly Tyr Pro  Ala Gly Val 
    2510                 2515                 2520             


Lys Gln  Lys Cys Leu Arg Ser  Gln Thr Ser Phe Arg  Gly Cys Leu 
    2525                 2530                 2535             


Arg Lys  Leu Ala Leu Ile Lys  Ser Pro Gln Val Gln  Ser Phe Asp 
    2540                 2545                 2550             


Phe Ser  Arg Ala Phe Glu Leu  His Gly Val Phe Leu  His Ser Cys 
    2555                 2560                 2565             


Pro Gly  Thr Glu Ser 
    2570             


<210>  797
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  797

Cys Val Cys Asn Gly His Ala Glu Val Cys Asn Ile Asn Asn Pro Glu 
1               5                   10                  15      


Lys Leu Phe Arg Cys Glu Cys Gln His His Thr Cys Gly Glu Thr Cys 
            20                  25                  30          


Asp Arg Cys Cys Thr Gly Tyr Asn Gln Arg Arg Trp Arg Pro Ala Ala 
        35                  40                  45              


Trp Glu Gln Ser His Glu Cys Glu Ala Cys Asn Cys His Gly His Ala 
    50                  55                  60                  


Ser Asn Cys Tyr Tyr Asp Pro Asp Val Glu Arg Gln Gln Ala Ser Leu 
65                  70                  75                  80  


Asn Thr Gln Gly Ile Tyr Ala Gly Gly Gly Val Cys Ile Asn Cys Gln 
                85                  90                  95      


His Asn Thr Ala Gly Val Asn Cys Glu Gln Cys Ala Lys Gly Tyr Tyr 
            100                 105                 110         


Arg Pro Tyr Gly Val Pro Val Asp Ala Pro Asp Gly Cys Ile Pro Cys 
        115                 120                 125             


Ser Cys Asp Pro Glu His Ala Asp Gly Cys Glu Gln Gly Ser Gly Arg 
    130                 135                 140                 


Cys His Cys Lys Pro Asn Phe His Gly Asp Asn Cys Glu Lys Cys Ala 
145                 150                 155                 160 


Ile Gly Tyr Tyr Asn Phe Pro Phe Cys Leu Arg 
                165                 170     


<210>  798
<211>  1765
<212>  PRT
<213>  Homo Sapiens

<400>  798

Gln Glu Pro Glu Phe Ser Tyr Gly Cys Ala Glu Gly Ser Cys Tyr Pro 
1               5                   10                  15      


Ala Thr Gly Asp Leu Leu Ile Gly Arg Ala Gln Lys Leu Ser Val Thr 
            20                  25                  30          


Ser Thr Cys Gly Leu His Lys Pro Glu Pro Tyr Cys Ile Val Ser His 
        35                  40                  45              


Leu Gln Glu Asp Lys Lys Cys Phe Ile Cys Asn Ser Gln Asp Pro Tyr 
    50                  55                  60                  


His Glu Thr Leu Asn Pro Asp Ser His Leu Ile Glu Asn Val Val Thr 
65                  70                  75                  80  


Thr Phe Ala Pro Asn Arg Leu Lys Ile Trp Trp Gln Ser Glu Asn Gly 
                85                  90                  95      


Val Glu Asn Val Thr Ile Gln Leu Asp Leu Glu Ala Glu Phe His Phe 
            100                 105                 110         


Thr His Leu Ile Met Thr Phe Lys Thr Phe Arg Pro Ala Ala Met Leu 
        115                 120                 125             


Ile Glu Arg Ser Ser Asp Phe Gly Lys Thr Trp Gly Val Tyr Arg Tyr 
    130                 135                 140                 


Phe Ala Tyr Asp Cys Glu Ala Ser Phe Pro Gly Ile Ser Thr Gly Pro 
145                 150                 155                 160 


Met Lys Lys Val Asp Asp Ile Ile Cys Asp Ser Arg Tyr Ser Asp Ile 
                165                 170                 175     


Glu Pro Ser Thr Glu Gly Glu Val Ile Phe Arg Ala Leu Asp Pro Ala 
            180                 185                 190         


Phe Lys Ile Glu Asp Pro Tyr Ser Pro Arg Ile Gln Asn Leu Leu Lys 
        195                 200                 205             


Ile Thr Asn Leu Arg Ile Lys Phe Val Lys Leu His Thr Leu Gly Asp 
    210                 215                 220                 


Asn Leu Leu Asp Ser Arg Met Glu Ile Arg Glu Lys Tyr Tyr Tyr Ala 
225                 230                 235                 240 


Val Tyr Asp Met Val Val Arg Gly Asn Cys Phe Cys Tyr Gly His Ala 
                245                 250                 255     


Ser Glu Cys Ala Pro Val Asp Gly Phe Asn Glu Glu Val Glu Gly Met 
            260                 265                 270         


Val His Gly His Cys Met Cys Arg His Asn Thr Lys Gly Leu Asn Cys 
        275                 280                 285             


Glu Leu Cys Met Asp Phe Tyr His Asp Leu Pro Trp Arg Pro Ala Glu 
    290                 295                 300                 


Gly Arg Asn Ser Asn Ala Cys Lys Lys Cys Asn Cys Asn Glu His Ser 
305                 310                 315                 320 


Ile Ser Cys His Phe Asp Met Ala Val Tyr Leu Ala Thr Gly Asn Val 
                325                 330                 335     


Ser Gly Gly Val Cys Asp Asp Cys Gln His Asn Thr Met Gly Arg Asn 
            340                 345                 350         


Cys Glu Gln Cys Lys Pro Phe Tyr Tyr Gln His Pro Glu Arg Asp Ile 
        355                 360                 365             


Arg Asp Pro Asn Phe Cys Glu Arg Cys Thr Cys Asp Pro Ala Gly Ser 
    370                 375                 380                 


Gln Asn Glu Gly Ile Cys Asp Ser Tyr Thr Asp Phe Ser Thr Gly Leu 
385                 390                 395                 400 


Ile Ala Gly Gln Cys Arg Cys Lys Leu Asn Val Glu Gly Glu His Cys 
                405                 410                 415     


Asp Val Cys Lys Glu Gly Phe Tyr Asp Leu Ser Ser Glu Asp Pro Phe 
            420                 425                 430         


Gly Cys Lys Ser Cys Ala Cys Asn Pro Leu Gly Thr Ile Pro Gly Gly 
        435                 440                 445             


Asn Pro Cys Asp Ser Glu Thr Gly His Cys Tyr Cys Lys Arg Leu Val 
    450                 455                 460                 


Thr Gly Gln His Cys Asp Gln Cys Leu Pro Glu His Trp Gly Leu Ser 
465                 470                 475                 480 


Asn Asp Leu Asp Gly Cys Arg Pro Cys Asp Cys Asp Leu Gly Gly Ala 
                485                 490                 495     


Leu Asn Asn Ser Cys Phe Ala Glu Ser Gly Gln Cys Ser Cys Arg Pro 
            500                 505                 510         


His Met Ile Gly Arg Gln Cys Asn Glu Val Glu Pro Gly Tyr Tyr Phe 
        515                 520                 525             


Ala Thr Leu Asp His Tyr Leu Tyr Glu Ala Glu Glu Ala Asn Leu Gly 
    530                 535                 540                 


Pro Gly Val Ser Ile Val Glu Arg Gln Tyr Ile Gln Asp Arg Ile Pro 
545                 550                 555                 560 


Ser Trp Thr Gly Ala Gly Phe Val Arg Val Pro Glu Gly Ala Tyr Leu 
                565                 570                 575     


Glu Phe Phe Ile Asp Asn Ile Pro Tyr Ser Met Glu Tyr Asp Ile Leu 
            580                 585                 590         


Ile Arg Tyr Glu Pro Gln Leu Pro Asp His Trp Glu Lys Ala Val Ile 
        595                 600                 605             


Thr Val Gln Arg Pro Gly Arg Ile Pro Thr Ser Ser Arg Cys Gly Asn 
    610                 615                 620                 


Thr Ile Pro Asp Asp Asp Asn Gln Val Val Ser Leu Ser Pro Gly Ser 
625                 630                 635                 640 


Arg Tyr Val Val Leu Pro Arg Pro Val Cys Phe Glu Lys Gly Thr Asn 
                645                 650                 655     


Tyr Thr Val Arg Leu Glu Leu Pro Gln Tyr Thr Ser Ser Asp Ser Asp 
            660                 665                 670         


Val Glu Ser Pro Tyr Thr Leu Ile Asp Ser Leu Val Leu Met Pro Tyr 
        675                 680                 685             


Cys Lys Ser Leu Asp Ile Phe Thr Val Gly Gly Ser Gly Asp Gly Val 
    690                 695                 700                 


Val Thr Asn Ser Ala Trp Glu Thr Phe Gln Arg Tyr Arg Cys Leu Glu 
705                 710                 715                 720 


Asn Ser Arg Ser Val Val Lys Thr Pro Met Thr Asp Val Cys Arg Asn 
                725                 730                 735     


Ile Ile Phe Ser Ile Ser Ala Leu Leu His Gln Thr Gly Leu Ala Cys 
            740                 745                 750         


Glu Cys Asp Pro Gln Gly Ser Leu Ser Ser Val Cys Asp Pro Asn Gly 
        755                 760                 765             


Gly Gln Cys Gln Cys Arg Pro Asn Val Val Gly Arg Thr Cys Asn Arg 
    770                 775                 780                 


Cys Ala Pro Gly Thr Phe Gly Phe Gly Pro Ser Gly Cys Lys Pro Cys 
785                 790                 795                 800 


Glu Cys His Leu Gln Gly Ser Val Asn Ala Phe Cys Asn Pro Val Thr 
                805                 810                 815     


Gly Gln Cys His Cys Phe Gln Gly Val Tyr Ala Arg Gln Cys Asp Arg 
            820                 825                 830         


Cys Leu Pro Gly His Trp Gly Phe Pro Ser Cys Gln Pro Cys Gln Cys 
        835                 840                 845             


Asn Gly His Ala Asp Asp Cys Asp Pro Val Thr Gly Glu Cys Leu Asn 
    850                 855                 860                 


Cys Gln Asp Tyr Thr Met Gly His Asn Cys Glu Arg Cys Leu Ala Gly 
865                 870                 875                 880 


Tyr Tyr Gly Asp Pro Ile Ile Gly Ser Gly Asp His Cys Arg Pro Cys 
                885                 890                 895     


Pro Cys Pro Asp Gly Pro Asp Ser Gly Arg Gln Phe Ala Arg Ser Cys 
            900                 905                 910         


Tyr Gln Asp Pro Val Thr Leu Gln Leu Ala Cys Val Cys Asp Pro Gly 
        915                 920                 925             


Tyr Ile Gly Ser Arg Cys Asp Asp Cys Ala Ser Gly Tyr Phe Gly Asn 
    930                 935                 940                 


Pro Ser Glu Val Gly Gly Ser Cys Gln Pro Cys Gln Cys His Asn Asn 
945                 950                 955                 960 


Ile Asp Thr Thr Asp Pro Glu Ala Cys Asp Lys Glu Thr Gly Arg Cys 
                965                 970                 975     


Leu Lys Cys Leu Tyr His Thr Glu Gly Glu His Cys Gln Phe Cys Arg 
            980                 985                 990         


Phe Gly Tyr Tyr Gly Asp Ala Leu  Gln Gln Asp Cys Arg  Lys Cys Val 
        995                 1000                 1005             


Cys Asn  Tyr Leu Gly Thr Val  Gln Glu His Cys Asn  Gly Ser Asp 
    1010                 1015                 1020             


Cys Gln  Cys Asp Lys Ala Thr  Gly Gln Cys Leu Cys  Leu Pro Asn 
    1025                 1030                 1035             


Val Ile  Gly Gln Asn Cys Asp  Arg Cys Ala Pro Asn  Thr Trp Gln 
    1040                 1045                 1050             


Leu Ala  Ser Gly Thr Gly Cys  Asp Pro Cys Asn Cys  Asn Ala Ala 
    1055                 1060                 1065             


His Ser  Phe Gly Pro Ser Cys  Asn Glu Phe Thr Gly  Gln Cys Gln 
    1070                 1075                 1080             


Cys Met  Pro Gly Phe Gly Gly  Arg Thr Cys Ser Glu  Cys Gln Glu 
    1085                 1090                 1095             


Leu Phe  Trp Gly Asp Pro Asp  Val Glu Cys Arg Ala  Cys Asp Cys 
    1100                 1105                 1110             


Asp Pro  Arg Gly Ile Glu Thr  Pro Gln Cys Asp Gln  Ser Thr Gly 
    1115                 1120                 1125             


Gln Cys  Val Cys Val Glu Gly  Val Glu Gly Pro Arg  Cys Asp Lys 
    1130                 1135                 1140             


Cys Thr  Arg Gly Tyr Ser Gly  Val Phe Pro Asp Cys  Thr Pro Cys 
    1145                 1150                 1155             


His Gln  Cys Phe Ala Leu Trp  Asp Val Ile Ile Ala  Glu Leu Thr 
    1160                 1165                 1170             


Asn Arg  Thr His Arg Phe Leu  Glu Lys Ala Lys Ala  Leu Lys Ile 
    1175                 1180                 1185             


Ser Gly  Val Ile Gly Pro Tyr  Arg Glu Thr Val Asp  Ser Val Glu 
    1190                 1195                 1200             


Arg Lys  Val Ser Glu Ile Lys  Asp Ile Leu Ala Gln  Ser Pro Ala 
    1205                 1210                 1215             


Ala Glu  Pro Leu Lys Asn Ile  Gly Asn Leu Phe Glu  Glu Ala Glu 
    1220                 1225                 1230             


Lys Leu  Ile Lys Asp Val Thr  Glu Met Met Ala Gln  Val Glu Val 
    1235                 1240                 1245             


Lys Leu  Ser Asp Thr Thr Ser  Gln Ser Asn Ser Thr  Ala Lys Glu 
    1250                 1255                 1260             


Leu Asp  Ser Leu Gln Thr Glu  Ala Glu Ser Leu Asp  Asn Thr Val 
    1265                 1270                 1275             


Lys Glu  Leu Ala Glu Gln Leu  Glu Phe Ile Lys Asn  Ser Asp Ile 
    1280                 1285                 1290             


Arg Gly  Ala Leu Asp Ser Ile  Thr Lys Tyr Phe Gln  Met Ser Leu 
    1295                 1300                 1305             


Glu Ala  Glu Glu Arg Val Asn  Ala Ser Thr Thr Glu  Pro Asn Ser 
    1310                 1315                 1320             


Thr Val  Glu Gln Ser Ala Leu  Met Arg Asp Arg Val  Glu Asp Val 
    1325                 1330                 1335             


Met Met  Glu Arg Glu Ser Gln  Phe Lys Glu Lys Gln  Glu Glu Gln 
    1340                 1345                 1350             


Ala Arg  Leu Leu Asp Glu Leu  Ala Gly Lys Leu Gln  Ser Leu Asp 
    1355                 1360                 1365             


Leu Ser  Ala Ala Ala Glu Met  Thr Cys Gly Thr Pro  Pro Gly Ala 
    1370                 1375                 1380             


Ser Cys  Ser Glu Thr Glu Cys  Gly Gly Pro Asn Cys  Arg Thr Asp 
    1385                 1390                 1395             


Glu Gly  Glu Arg Lys Cys Gly  Gly Pro Gly Cys Gly  Gly Leu Val 
    1400                 1405                 1410             


Thr Val  Ala His Asn Ala Trp  Gln Lys Ala Met Asp  Leu Asp Gln 
    1415                 1420                 1425             


Asp Val  Leu Ser Ala Leu Ala  Glu Val Glu Gln Leu  Ser Lys Met 
    1430                 1435                 1440             


Val Ser  Glu Ala Lys Leu Arg  Ala Asp Glu Ala Lys  Gln Ser Ala 
    1445                 1450                 1455             


Glu Asp  Ile Leu Leu Lys Thr  Asn Ala Thr Lys Glu  Lys Met Asp 
    1460                 1465                 1470             


Lys Ser  Asn Glu Glu Leu Arg  Asn Leu Ile Lys Gln  Ile Arg Asn 
    1475                 1480                 1485             


Phe Leu  Thr Gln Asp Ser Ala  Asp Leu Asp Ser Ile  Glu Ala Val 
    1490                 1495                 1500             


Ala Asn  Glu Val Leu Lys Met  Glu Met Pro Ser Thr  Pro Gln Gln 
    1505                 1510                 1515             


Leu Gln  Asn Leu Thr Glu Asp  Ile Arg Glu Arg Val  Glu Ser Leu 
    1520                 1525                 1530             


Ser Gln  Val Glu Val Ile Leu  Gln His Ser Ala Ala  Asp Ile Ala 
    1535                 1540                 1545             


Arg Ala  Glu Met Leu Leu Glu  Glu Ala Lys Arg Ala  Ser Lys Ser 
    1550                 1555                 1560             


Ala Thr  Asp Val Lys Val Thr  Ala Asp Met Val Lys  Glu Ala Leu 
    1565                 1570                 1575             


Glu Glu  Ala Glu Lys Ala Gln  Val Ala Ala Glu Lys  Ala Ile Lys 
    1580                 1585                 1590             


Gln Ala  Asp Glu Asp Ile Gln  Gly Thr Gln Asn Leu  Leu Thr Ser 
    1595                 1600                 1605             


Ile Glu  Ser Glu Thr Ala Ala  Ser Glu Glu Thr Leu  Phe Asn Ala 
    1610                 1615                 1620             


Ser Gln  Arg Ile Ser Glu Leu  Glu Arg Asn Val Glu  Glu Leu Lys 
    1625                 1630                 1635             


Arg Lys  Ala Ala Gln Asn Ser  Gly Glu Ala Glu Tyr  Ile Glu Lys 
    1640                 1645                 1650             


Val Val  Tyr Thr Val Lys Gln  Ser Ala Glu Asp Val  Lys Lys Thr 
    1655                 1660                 1665             


Leu Asp  Gly Glu Leu Asp Glu  Lys Tyr Lys Lys Val  Glu Asn Leu 
    1670                 1675                 1680             


Ile Ala  Lys Lys Thr Glu Glu  Ser Ala Asp Ala Arg  Arg Lys Ala 
    1685                 1690                 1695             


Glu Met  Leu Gln Asn Glu Ala  Lys Thr Leu Leu Ala  Gln Ala Asn 
    1700                 1705                 1710             


Ser Lys  Leu Gln Leu Leu Lys  Asp Leu Glu Arg Lys  Tyr Glu Asp 
    1715                 1720                 1725             


Asn Gln  Arg Tyr Leu Glu Asp  Lys Ala Gln Glu Leu  Ala Arg Leu 
    1730                 1735                 1740             


Glu Gly  Glu Val Arg Ser Leu  Leu Lys Asp Ile Ser  Gln Lys Val 
    1745                 1750                 1755             


Ala Val  Tyr Ser Thr Cys Leu  
    1760                 1765 


<210>  799
<211>  1155
<212>  PRT
<213>  Homo Sapiens

<400>  799

Gln Gln Ala Cys Ser Arg Gly Ala Cys Tyr Pro Pro Val Gly Asp Leu 
1               5                   10                  15      


Leu Val Gly Arg Thr Arg Phe Leu Arg Ala Ser Ser Thr Cys Gly Leu 
            20                  25                  30          


Thr Lys Pro Glu Thr Tyr Cys Thr Gln Tyr Gly Glu Trp Gln Met Lys 
        35                  40                  45              


Cys Cys Lys Cys Asp Ser Arg Gln Pro His Asn Tyr Tyr Ser His Arg 
    50                  55                  60                  


Val Glu Asn Val Ala Ser Ser Ser Gly Pro Met Arg Trp Trp Gln Ser 
65                  70                  75                  80  


Gln Asn Asp Val Asn Pro Val Ser Leu Gln Leu Asp Leu Asp Arg Arg 
                85                  90                  95      


Phe Gln Leu Gln Glu Val Met Met Glu Phe Gln Gly Pro Met Pro Ala 
            100                 105                 110         


Gly Met Leu Ile Glu Arg Ser Ser Asp Phe Gly Lys Thr Trp Arg Val 
        115                 120                 125             


Tyr Gln Tyr Leu Ala Ala Asp Cys Thr Ser Thr Phe Pro Arg Val Arg 
    130                 135                 140                 


Gln Gly Arg Pro Gln Ser Trp Gln Asp Val Arg Cys Gln Ser Leu Pro 
145                 150                 155                 160 


Gln Arg Pro Asn Ala Arg Leu Asn Gly Gly Lys Val Gln Leu Asn Leu 
                165                 170                 175     


Met Asp Leu Val Ser Gly Ile Pro Ala Thr Gln Ser Gln Lys Ile Gln 
            180                 185                 190         


Glu Val Gly Glu Ile Thr Asn Leu Arg Val Asn Phe Thr Arg Leu Ala 
        195                 200                 205             


Pro Val Pro Gln Arg Gly Tyr His Pro Pro Ser Ala Tyr Tyr Ala Val 
    210                 215                 220                 


Ser Gln Leu Arg Leu Gln Gly Ser Cys Phe Cys His Gly His Ala Asp 
225                 230                 235                 240 


Arg Cys Ala Pro Lys Pro Gly Ala Ser Ala Gly Pro Ser Thr Ala Val 
                245                 250                 255     


Gln Val His Asp Val Cys Val Cys Gln His Asn Thr Ala Gly Pro Asn 
            260                 265                 270         


Cys Glu Arg Cys Ala Pro Phe Tyr Asn Asn Arg Pro Trp Arg Pro Ala 
        275                 280                 285             


Glu Gly Gln Asp Ala His Glu Cys Gln Arg Cys Asp Cys Asn Gly His 
    290                 295                 300                 


Ser Glu Thr Cys His Phe Asp Pro Ala Val Phe Ala Ala Ser Gln Gly 
305                 310                 315                 320 


Ala Tyr Gly Gly Val Cys Asp Asn Cys Arg Asp His Thr Glu Gly Lys 
                325                 330                 335     


Asn Cys Glu Arg Cys Gln Leu His Tyr Phe Arg Asn Arg Arg Pro Gly 
            340                 345                 350         


Ala Ser Ile Gln Glu Thr Cys Ile Ser Cys Glu Cys Asp Pro Asp Gly 
        355                 360                 365             


Ala Val Pro Gly Ala Pro Cys Asp Pro Val Thr Gly Gln Cys Val Cys 
    370                 375                 380                 


Lys Glu His Val Gln Gly Glu Arg Cys Asp Leu Cys Lys Pro Gly Phe 
385                 390                 395                 400 


Thr Gly Leu Thr Tyr Ala Asn Pro Gln Gly Cys His Arg Cys Asp Cys 
                405                 410                 415     


Asn Ile Leu Gly Ser Arg Arg Asp Met Pro Cys Asp Glu Glu Ser Gly 
            420                 425                 430         


Arg Cys Leu Cys Leu Pro Asn Val Val Gly Pro Lys Cys Asp Gln Cys 
        435                 440                 445             


Ala Pro Tyr His Trp Lys Leu Ala Ser Gly Gln Gly Cys Glu Pro Cys 
    450                 455                 460                 


Ala Cys Asp Pro His Asn Ser Leu Ser Pro Gln Cys Asn Gln Phe Thr 
465                 470                 475                 480 


Gly Gln Cys Pro Cys Arg Glu Gly Phe Gly Gly Leu Met Cys Ser Ala 
                485                 490                 495     


Ala Ala Ile Arg Gln Cys Pro Asp Arg Thr Tyr Gly Asp Val Ala Thr 
            500                 505                 510         


Gly Cys Arg Ala Cys Asp Cys Asp Phe Arg Gly Thr Glu Gly Pro Gly 
        515                 520                 525             


Cys Asp Lys Ala Ser Gly Arg Cys Leu Cys Arg Pro Gly Leu Thr Gly 
    530                 535                 540                 


Pro Arg Cys Asp Gln Cys Gln Arg Gly Tyr Cys Asn Arg Tyr Pro Val 
545                 550                 555                 560 


Cys Val Ala Cys His Pro Cys Phe Gln Thr Tyr Asp Ala Asp Leu Arg 
                565                 570                 575     


Glu Gln Ala Leu Arg Phe Gly Arg Leu Arg Asn Ala Thr Ala Ser Leu 
            580                 585                 590         


Trp Ser Gly Pro Gly Leu Glu Asp Arg Gly Leu Ala Ser Arg Ile Leu 
        595                 600                 605             


Asp Ala Lys Ser Lys Ile Glu Gln Ile Arg Ala Val Leu Ser Ser Pro 
    610                 615                 620                 


Ala Val Thr Glu Gln Glu Val Ala Gln Val Ala Ser Ala Ile Leu Ser 
625                 630                 635                 640 


Leu Arg Arg Thr Leu Gln Gly Leu Gln Leu Asp Leu Pro Leu Glu Glu 
                645                 650                 655     


Glu Thr Leu Ser Leu Pro Arg Asp Leu Glu Ser Leu Asp Arg Ser Phe 
            660                 665                 670         


Asn Gly Leu Leu Thr Met Tyr Gln Arg Lys Arg Glu Gln Phe Glu Lys 
        675                 680                 685             


Ile Ser Ser Ala Asp Pro Ser Gly Ala Phe Arg Met Leu Ser Thr Ala 
    690                 695                 700                 


Tyr Glu Gln Ser Ala Gln Ala Ala Gln Gln Val Ser Asp Ser Ser Arg 
705                 710                 715                 720 


Leu Leu Asp Gln Leu Arg Asp Ser Arg Arg Glu Ala Glu Arg Leu Val 
                725                 730                 735     


Arg Gln Ala Gly Gly Gly Gly Gly Thr Gly Ser Pro Lys Leu Val Ala 
            740                 745                 750         


Leu Arg Leu Glu Met Ser Ser Leu Pro Asp Leu Thr Pro Thr Phe Asn 
        755                 760                 765             


Lys Leu Cys Gly Asn Ser Arg Gln Met Ala Cys Thr Pro Ile Ser Cys 
    770                 775                 780                 


Pro Gly Glu Leu Cys Pro Gln Asp Asn Gly Thr Ala Cys Gly Ser Arg 
785                 790                 795                 800 


Cys Arg Gly Val Leu Pro Arg Ala Gly Gly Ala Phe Leu Met Ala Gly 
                805                 810                 815     


Gln Val Ala Glu Gln Leu Arg Gly Phe Asn Ala Gln Leu Gln Arg Thr 
            820                 825                 830         


Arg Gln Met Ile Arg Ala Ala Glu Glu Ser Ala Ser Gln Ile Gln Ser 
        835                 840                 845             


Ser Ala Gln Arg Leu Glu Thr Gln Val Ser Ala Ser Arg Ser Gln Met 
    850                 855                 860                 


Glu Glu Asp Val Arg Arg Thr Arg Leu Leu Ile Gln Gln Val Arg Asp 
865                 870                 875                 880 


Phe Leu Thr Asp Pro Asp Thr Asp Ala Ala Thr Ile Gln Glu Val Ser 
                885                 890                 895     


Glu Ala Val Leu Ala Leu Trp Leu Pro Thr Asp Ser Ala Thr Val Leu 
            900                 905                 910         


Gln Lys Met Asn Glu Ile Gln Ala Ile Ala Ala Arg Leu Pro Asn Val 
        915                 920                 925             


Asp Leu Val Leu Ser Gln Thr Lys Gln Asp Ile Ala Arg Ala Arg Arg 
    930                 935                 940                 


Leu Gln Ala Glu Ala Glu Glu Ala Arg Ser Arg Ala His Ala Val Glu 
945                 950                 955                 960 


Gly Gln Val Glu Asp Val Val Gly Asn Leu Arg Gln Gly Thr Val Ala 
                965                 970                 975     


Leu Gln Glu Ala Gln Asp Thr Met Gln Gly Thr Ser Arg Ser Leu Arg 
            980                 985                 990         


Leu Ile Gln Asp Arg Val Ala Glu  Val Gln Gln Val Leu  Arg Pro Ala 
        995                 1000                 1005             


Glu Lys  Leu Val Thr Ser Met  Thr Lys Gln Leu Gly  Asp Phe Trp 
    1010                 1015                 1020             


Thr Arg  Met Glu Glu Leu Arg  His Gln Ala Arg Gln  Gln Gly Ala 
    1025                 1030                 1035             


Glu Ala  Val Gln Ala Gln Gln  Leu Ala Glu Gly Ala  Ser Glu Gln 
    1040                 1045                 1050             


Ala Leu  Ser Ala Gln Glu Gly  Phe Glu Arg Ile Lys  Gln Lys Tyr 
    1055                 1060                 1065             


Ala Glu  Leu Lys Asp Arg Leu  Gly Gln Ser Ser Met  Leu Gly Glu 
    1070                 1075                 1080             


Gln Gly  Ala Arg Ile Gln Ser  Val Lys Thr Glu Ala  Glu Glu Leu 
    1085                 1090                 1095             


Phe Gly  Glu Thr Met Glu Met  Met Asp Arg Met Lys  Asp Met Glu 
    1100                 1105                 1110             


Leu Glu  Leu Leu Arg Gly Ser  Gln Ala Ile Met Leu  Arg Ser Ala 
    1115                 1120                 1125             


Asp Leu  Thr Gly Leu Glu Lys  Arg Val Glu Gln Ile  Arg Asp His 
    1130                 1135                 1140             


Ile Asn  Gly Arg Val Leu Tyr  Tyr Ala Thr Cys Lys  
    1145                 1150                 1155 


<210>  800
<211>  1742
<212>  PRT
<213>  Homo Sapiens

<400>  800

Gln Asp Asp Cys Asn Arg Gly Ala Cys His Pro Thr Thr Gly Asp Leu 
1               5                   10                  15      


Leu Val Gly Arg Asn Thr Gln Leu Met Ala Ser Ser Thr Cys Gly Leu 
            20                  25                  30          


Ser Arg Ala Gln Lys Tyr Cys Ile Leu Ser Tyr Leu Glu Gly Glu Gln 
        35                  40                  45              


Lys Cys Phe Ile Cys Asp Ser Arg Phe Pro Tyr Asp Pro Tyr Asp Gln 
    50                  55                  60                  


Pro Asn Ser His Thr Ile Glu Asn Val Ile Val Ser Phe Glu Pro Asp 
65                  70                  75                  80  


Arg Glu Lys Lys Trp Trp Gln Ser Glu Asn Gly Leu Asp His Val Ser 
                85                  90                  95      


Ile Arg Leu Asp Leu Glu Ala Leu Phe Arg Phe Ser His Leu Ile Leu 
            100                 105                 110         


Thr Phe Lys Thr Phe Arg Pro Ala Ala Met Leu Val Glu Arg Ser Thr 
        115                 120                 125             


Asp Tyr Gly His Asn Trp Lys Val Phe Lys Tyr Phe Ala Lys Asp Cys 
    130                 135                 140                 


Ala Thr Ser Phe Pro Asn Ile Thr Ser Gly Gln Ala Gln Gly Val Gly 
145                 150                 155                 160 


Asp Ile Val Cys Asp Ser Lys Tyr Ser Asp Ile Glu Pro Ser Thr Gly 
                165                 170                 175     


Gly Glu Val Val Leu Lys Val Leu Asp Pro Ser Phe Glu Ile Glu Asn 
            180                 185                 190         


Pro Tyr Ser Pro Tyr Ile Gln Asp Leu Val Thr Leu Thr Asn Leu Arg 
        195                 200                 205             


Ile Asn Phe Thr Lys Leu His Thr Leu Gly Asp Ala Leu Leu Gly Arg 
    210                 215                 220                 


Arg Gln Asn Asp Ser Leu Asp Lys Tyr Tyr Tyr Ala Leu Tyr Glu Met 
225                 230                 235                 240 


Ile Val Arg Gly Ser Cys Phe Cys Asn Gly His Ala Ser Glu Cys Arg 
                245                 250                 255     


Pro Met Gln Lys Met Arg Gly Asp Val Phe Ser Pro Pro Gly Met Val 
            260                 265                 270         


His Gly Gln Cys Val Cys Gln His Asn Thr Asp Gly Pro Asn Cys Glu 
        275                 280                 285             


Arg Cys Lys Asp Phe Phe Gln Asp Ala Pro Trp Arg Pro Ala Ala Asp 
    290                 295                 300                 


Leu Gln Asp Asn Ala Cys Arg Ser Cys Ser Cys Asn Ser His Ser Ser 
305                 310                 315                 320 


Arg Cys His Phe Asp Met Thr Thr Tyr Leu Ala Ser Gly Gly Leu Ser 
                325                 330                 335     


Gly Gly Val Cys Glu Asp Cys Gln His Asn Thr Glu Gly Gln His Cys 
            340                 345                 350         


Asp Arg Cys Arg Pro Leu Phe Tyr Arg Asp Pro Leu Lys Thr Ile Ser 
        355                 360                 365             


Asp Pro Tyr Ala Cys Ile Pro Cys Glu Cys Asp Pro Asp Gly Thr Ile 
    370                 375                 380                 


Ser Gly Gly Ile Cys Val Ser His Ser Asp Pro Ala Leu Gly Ser Val 
385                 390                 395                 400 


Ala Gly Gln Cys Leu Cys Lys Glu Asn Val Glu Gly Ala Lys Cys Asp 
                405                 410                 415     


Gln Cys Lys Pro Asn His Tyr Gly Leu Ser Ala Thr Asp Pro Leu Gly 
            420                 425                 430         


Cys Gln Pro Cys Asp Cys Asn Pro Leu Gly Ser Leu Pro Phe Leu Thr 
        435                 440                 445             


Cys Asp Val Asp Thr Gly Gln Cys Leu Cys Leu Ser Tyr Val Thr Gly 
    450                 455                 460                 


Ala His Cys Glu Glu Cys Thr Val Gly Tyr Trp Gly Leu Gly Asn His 
465                 470                 475                 480 


Leu His Gly Cys Ser Pro Cys Asp Cys Asp Ile Gly Gly Ala Tyr Ser 
                485                 490                 495     


Asn Val Cys Ser Pro Lys Asn Gly Gln Cys Glu Cys Arg Pro His Val 
            500                 505                 510         


Thr Gly Arg Ser Cys Ser Glu Pro Ala Pro Gly Tyr Phe Phe Ala Pro 
        515                 520                 525             


Leu Asn Phe Tyr Leu Tyr Glu Ala Glu Glu Ala Thr Thr Leu Gln Gly 
    530                 535                 540                 


Leu Ala Pro Leu Gly Ser Glu Thr Phe Gly Gln Ser Pro Ala Val His 
545                 550                 555                 560 


Val Val Leu Gly Glu Pro Val Pro Gly Asn Pro Val Thr Trp Thr Gly 
                565                 570                 575     


Pro Gly Phe Ala Arg Val Leu Pro Gly Ala Gly Leu Arg Phe Ala Val 
            580                 585                 590         


Asn Asn Ile Pro Phe Pro Val Asp Phe Thr Ile Ala Ile His Tyr Glu 
        595                 600                 605             


Thr Gln Ser Ala Ala Asp Trp Thr Val Gln Ile Val Val Asn Pro Pro 
    610                 615                 620                 


Gly Gly Ser Glu His Cys Ile Pro Lys Thr Leu Gln Ser Lys Pro Gln 
625                 630                 635                 640 


Ser Phe Ala Leu Pro Ala Ala Thr Arg Ile Met Leu Leu Pro Thr Pro 
                645                 650                 655     


Ile Cys Leu Glu Pro Asp Val Gln Tyr Ser Ile Asp Val Tyr Phe Ser 
            660                 665                 670         


Gln Pro Leu Gln Gly Glu Ser His Ala His Ser His Val Leu Val Asp 
        675                 680                 685             


Ser Leu Gly Leu Ile Pro Gln Ile Asn Ser Leu Glu Asn Phe Cys Ser 
    690                 695                 700                 


Lys Gln Asp Leu Asp Glu Tyr Gln Leu His Asn Cys Val Glu Ile Ala 
705                 710                 715                 720 


Ser Ala Met Gly Pro Gln Val Leu Pro Gly Ala Cys Glu Arg Leu Ile 
                725                 730                 735     


Ile Ser Met Ser Ala Lys Leu His Asp Gly Ala Val Ala Cys Lys Cys 
            740                 745                 750         


His Pro Gln Gly Ser Val Gly Ser Ser Cys Ser Arg Leu Gly Gly Gln 
        755                 760                 765             


Cys Gln Cys Lys Pro Leu Val Val Gly Arg Cys Cys Asp Arg Cys Ser 
    770                 775                 780                 


Thr Gly Ser Tyr Asp Leu Gly His His Gly Cys His Pro Cys His Cys 
785                 790                 795                 800 


His Pro Gln Gly Ser Lys Asp Thr Val Cys Asp Gln Val Thr Gly Gln 
                805                 810                 815     


Cys Pro Cys His Gly Glu Val Ser Gly Arg Arg Cys Asp Arg Cys Leu 
            820                 825                 830         


Ala Gly Tyr Phe Gly Phe Pro Ser Cys His Pro Cys Pro Cys Asn Arg 
        835                 840                 845             


Phe Ala Glu Leu Cys Asp Pro Glu Thr Gly Ser Cys Phe Asn Cys Gly 
    850                 855                 860                 


Gly Phe Thr Thr Gly Arg Asn Cys Glu Arg Cys Ile Asp Gly Tyr Tyr 
865                 870                 875                 880 


Gly Asn Pro Ser Ser Gly Gln Pro Cys Arg Pro Cys Leu Cys Pro Asp 
                885                 890                 895     


Asp Pro Ser Ser Asn Gln Tyr Phe Ala His Ser Cys Tyr Gln Asn Leu 
            900                 905                 910         


Trp Ser Ser Asp Val Ile Cys Asn Cys Leu Gln Gly Tyr Thr Gly Thr 
        915                 920                 925             


Gln Cys Gly Glu Cys Ser Thr Gly Phe Tyr Gly Asn Pro Arg Ile Ser 
    930                 935                 940                 


Gly Ala Pro Cys Gln Pro Cys Ala Cys Asn Asn Asn Ile Asp Val Thr 
945                 950                 955                 960 


Asp Pro Glu Ser Cys Ser Arg Val Thr Gly Glu Cys Leu Arg Cys Leu 
                965                 970                 975     


His Asn Thr Gln Gly Ala Asn Cys Gln Leu Cys Lys Pro Gly His Tyr 
            980                 985                 990         


Gly Ser Ala Leu Asn Gln Thr Cys  Arg Arg Cys Ser Cys  His Ala Ser 
        995                 1000                 1005             


Gly Val  Ser Pro Met Glu Cys  Pro Pro Gly Gly Gly  Ala Cys Leu 
    1010                 1015                 1020             


Cys Asp  Pro Val Thr Gly Ala  Cys Pro Cys Leu Pro  Asn Val Thr 
    1025                 1030                 1035             


Gly Leu  Ala Cys Asp Arg Cys  Ala Asp Gly Tyr Trp  Asn Leu Val 
    1040                 1045                 1050             


Pro Gly  Arg Gly Cys Gln Ser  Cys Asp Cys Asp Pro  Arg Thr Ser 
    1055                 1060                 1065             


Gln Ser  Ser His Cys Asp Gln  Leu Thr Gly Gln Cys  Pro Cys Lys 
    1070                 1075                 1080             


Leu Gly  Tyr Gly Gly Lys Arg  Cys Ser Glu Cys Gln  Glu Asn Tyr 
    1085                 1090                 1095             


Tyr Gly  Asp Pro Pro Gly Arg  Cys Ile Pro Cys Asp  Cys Asn Arg 
    1100                 1105                 1110             


Ala Gly  Thr Gln Lys Pro Ile  Cys Asp Pro Asp Thr  Gly Met Cys 
    1115                 1120                 1125             


Arg Cys  Arg Glu Gly Val Ser  Gly Gln Arg Cys Asp  Arg Cys Ala 
    1130                 1135                 1140             


Arg Gly  His Ser Gln Glu Phe  Pro Thr Cys Leu Gln  Cys His Leu 
    1145                 1150                 1155             


Cys Phe  Asp Gln Trp Asp His  Thr Ile Ser Ser Leu  Ser Lys Ala 
    1160                 1165                 1170             


Val Gln  Gly Leu Met Arg Leu  Ala Ala Asn Met Glu  Asp Lys Arg 
    1175                 1180                 1185             


Glu Thr  Leu Pro Val Cys Glu  Ala Asp Phe Lys Asp  Leu Arg Gly 
    1190                 1195                 1200             


Asn Val  Ser Glu Ile Glu Arg  Ile Leu Lys His Pro  Val Phe Pro 
    1205                 1210                 1215             


Ser Gly  Lys Phe Leu Lys Val  Lys Asp Tyr His Asp  Ser Val Arg 
    1220                 1225                 1230             


Arg Gln  Ile Met Gln Leu Asn  Glu Gln Leu Lys Ala  Val Tyr Glu 
    1235                 1240                 1245             


Phe Gln  Asp Leu Lys Asp Thr  Ile Glu Arg Ala Lys  Asn Glu Ala 
    1250                 1255                 1260             


Asp Leu  Leu Leu Glu Asp Leu  Gln Glu Glu Ile Asp  Leu Gln Ser 
    1265                 1270                 1275             


Ser Val  Leu Asn Ala Ser Ile  Ala Asp Ser Ser Glu  Asn Ile Lys 
    1280                 1285                 1290             


Lys Tyr  Tyr His Ile Ser Ser  Ser Ala Glu Lys Lys  Ile Asn Glu 
    1295                 1300                 1305             


Thr Ser  Ser Thr Ile Asn Thr  Ser Ala Asn Thr Arg  Asn Asp Leu 
    1310                 1315                 1320             


Leu Thr  Ile Leu Asp Thr Leu  Thr Ser Lys Gly Asn  Leu Ser Leu 
    1325                 1330                 1335             


Glu Arg  Leu Lys Gln Ile Lys  Ile Pro Asp Ile Gln  Ile Leu Asn 
    1340                 1345                 1350             


Glu Lys  Val Cys Gly Asp Pro  Gly Asn Val Pro Cys  Val Pro Leu 
    1355                 1360                 1365             


Pro Cys  Gly Gly Ala Leu Cys  Thr Gly Arg Lys Gly  His Arg Lys 
    1370                 1375                 1380             


Cys Arg  Gly Pro Gly Cys His  Gly Ser Leu Thr Leu  Ser Thr Asn 
    1385                 1390                 1395             


Ala Leu  Gln Lys Ala Gln Glu  Ala Lys Ser Ile Ile  Arg Asn Leu 
    1400                 1405                 1410             


Asp Lys  Gln Val Arg Gly Leu  Lys Asn Gln Ile Glu  Ser Ile Ser 
    1415                 1420                 1425             


Glu Gln  Ala Glu Val Ser Lys  Asn Asn Ala Leu Gln  Leu Arg Glu 
    1430                 1435                 1440             


Lys Leu  Gly Asn Ile Arg Asn  Gln Ser Asp Ser Glu  Glu Glu Asn 
    1445                 1450                 1455             


Ile Asn  Leu Phe Ile Lys Lys  Val Lys Asn Phe Leu  Leu Glu Glu 
    1460                 1465                 1470             


Asn Val  Pro Pro Glu Asp Ile  Glu Lys Val Ala Asn  Gly Val Leu 
    1475                 1480                 1485             


Asp Ile  His Leu Pro Ile Pro  Ser Gln Asn Leu Thr  Asp Glu Leu 
    1490                 1495                 1500             


Val Lys  Ile Gln Lys His Met  Gln Leu Cys Glu Asp  Tyr Arg Thr 
    1505                 1510                 1515             


Asp Glu  Asn Arg Leu Asn Glu  Glu Ala Asp Gly Ala  Gln Lys Leu 
    1520                 1525                 1530             


Leu Val  Lys Ala Lys Ala Ala  Glu Lys Ala Ala Asn  Ile Leu Leu 
    1535                 1540                 1545             


Asn Leu  Asp Lys Thr Leu Asn  Gln Leu Gln Gln Ala  Gln Ile Thr 
    1550                 1555                 1560             


Gln Gly  Arg Ala Asn Ser Thr  Ile Thr Gln Leu Thr  Ala Asn Ile 
    1565                 1570                 1575             


Thr Lys  Ile Lys Lys Asn Val  Leu Gln Ala Glu Asn  Gln Thr Arg 
    1580                 1585                 1590             


Glu Met  Lys Ser Glu Leu Glu  Leu Ala Lys Gln Arg  Ser Gly Leu 
    1595                 1600                 1605             


Glu Asp  Gly Leu Ser Leu Leu  Gln Thr Lys Leu Gln  Arg His Gln 
    1610                 1615                 1620             


Asp His  Ala Val Asn Ala Lys  Val Gln Ala Glu Ser  Ala Gln His 
    1625                 1630                 1635             


Gln Ala  Gly Ser Leu Glu Lys  Glu Phe Val Glu Leu  Lys Lys Gln 
    1640                 1645                 1650             


Tyr Ala  Ile Leu Gln Arg Lys  Thr Ser Thr Thr Gly  Leu Thr Lys 
    1655                 1660                 1665             


Glu Thr  Leu Gly Lys Val Lys  Gln Leu Lys Asp Ala  Ala Glu Lys 
    1670                 1675                 1680             


Leu Ala  Gly Asp Thr Glu Ala  Lys Ile Arg Arg Ile  Thr Asp Leu 
    1685                 1690                 1695             


Glu Arg  Lys Ile Gln Asp Leu  Asn Leu Ser Arg Gln  Ala Lys Ala 
    1700                 1705                 1710             


Asp Gln  Leu Arg Ile Leu Glu  Asp Gln Val Val Ala  Ile Lys Asn 
    1715                 1720                 1725             


Glu Ile  Val Glu Gln Glu Lys  Lys Tyr Ala Arg Cys  Tyr Ser 
    1730                 1735                 1740         


<210>  801
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  801

Gln Ala Ala Met Asp Glu Cys Thr Asp Glu Gly Gly Arg Pro Gln Arg 
1               5                   10                  15      


Cys Met Pro Glu Phe Val Asn Ala Ala Phe Asn Val Thr Val Val Ala 
            20                  25                  30          


Thr Asn Thr Cys Gly Thr Pro Pro Glu Glu Tyr Cys Val Gln Thr Gly 
        35                  40                  45              


Val Thr Gly Val Thr Lys Ser Cys His Leu Cys Asp Ala Gly Gln Pro 
    50                  55                  60                  


His Leu Gln His Gly Ala Ala Phe Leu Thr Asp Tyr Asn Asn Gln Ala 
65                  70                  75                  80  


Asp Thr Thr Trp Trp Gln Ser Gln Thr Met Leu Ala Gly Val Gln Tyr 
                85                  90                  95      


Pro Ser Ser Ile Asn Leu Thr Leu His Leu Gly Lys Ala Phe Asp Ile 
            100                 105                 110         


Thr Tyr Val Arg Leu Lys Phe His Thr Ser Arg Pro Glu Ser Phe Ala 
        115                 120                 125             


Ile Tyr Lys Arg Thr Arg Glu Asp Gly Pro Trp Ile Pro Tyr Gln Tyr 
    130                 135                 140                 


Tyr Ser Gly Ser Cys Glu Asn Thr Tyr Ser Lys Ala Asn Arg Gly Phe 
145                 150                 155                 160 


Ile Arg Thr Gly Gly Asp Glu Gln Gln Ala Leu Cys Thr Asp Glu Phe 
                165                 170                 175     


Ser Asp Ile Ser Pro Leu Thr Gly Gly Asn Val Ala Phe Ser Thr Leu 
            180                 185                 190         


Glu Gly Arg Pro Ser Ala Tyr Asn Phe Asp Asn Ser Pro Val Leu Gln 
        195                 200                 205             


Val Asn Ser His Arg Leu Ala 
    210                 215 


<210>  802
<211>  1090
<212>  PRT
<213>  Homo Sapiens

<400>  802

Thr Ser Arg Arg Glu Val Cys Asp Cys Asn Gly Lys Ser Arg Gln Cys 
1               5                   10                  15      


Ile Phe Asp Arg Glu Leu His Arg Gln Thr Gly Asn Gly Phe Arg Cys 
            20                  25                  30          


Leu Asn Cys Asn Asp Asn Thr Asp Gly Ile His Cys Glu Lys Cys Lys 
        35                  40                  45              


Asn Gly Phe Tyr Arg His Arg Glu Arg Asp Arg Cys Leu Pro Cys Asn 
    50                  55                  60                  


Cys Asn Ser Lys Gly Ser Leu Ser Ala Arg Cys Asp Asn Ser Gly Arg 
65                  70                  75                  80  


Cys Ser Cys Lys Pro Gly Val Thr Gly Ala Arg Cys Asp Arg Cys Leu 
                85                  90                  95      


Pro Gly Phe His Met Leu Thr Asp Ala Gly Cys Thr Gln Asp Gln Arg 
            100                 105                 110         


Leu Leu Asp Ser Lys Cys Asp Cys Asp Pro Ala Gly Ile Ala Gly Pro 
        115                 120                 125             


Cys Asp Ala Gly Arg Cys Val Cys Lys Pro Ala Val Thr Gly Glu Arg 
    130                 135                 140                 


Cys Asp Arg Cys Arg Ser Gly Tyr Tyr Asn Leu Asp Gly Gly Asn Pro 
145                 150                 155                 160 


Glu Gly Cys Thr Gln Cys Phe Cys Tyr Gly His Ser Ala Ser Cys Arg 
                165                 170                 175     


Ser Ser Ala Glu Tyr Ser Val His Lys Ile Thr Ser Thr Phe His Gln 
            180                 185                 190         


Asp Val Asp Gly Trp Lys Ala Val Gln Arg Asn Gly Ser Pro Ala Lys 
        195                 200                 205             


Leu Gln Trp Ser Gln Arg His Gln Asp Val Phe Ser Ser Ala Gln Arg 
    210                 215                 220                 


Leu Asp Pro Val Tyr Phe Val Ala Pro Ala Lys Phe Leu Gly Asn Gln 
225                 230                 235                 240 


Gln Val Ser Tyr Gly Gln Ser Leu Ser Phe Asp Tyr Arg Val Asp Arg 
                245                 250                 255     


Gly Gly Arg His Pro Ser Ala His Asp Val Ile Leu Glu Gly Ala Gly 
            260                 265                 270         


Leu Arg Ile Thr Ala Pro Leu Met Pro Leu Gly Lys Thr Leu Pro Cys 
        275                 280                 285             


Gly Leu Thr Lys Thr Tyr Thr Phe Arg Leu Asn Glu His Pro Ser Asn 
    290                 295                 300                 


Asn Trp Ser Pro Gln Leu Ser Tyr Phe Glu Tyr Arg Arg Leu Leu Arg 
305                 310                 315                 320 


Asn Leu Thr Ala Leu Arg Ile Arg Ala Thr Tyr Gly Glu Tyr Ser Thr 
                325                 330                 335     


Gly Tyr Ile Asp Asn Val Thr Leu Ile Ser Ala Arg Pro Val Ser Gly 
            340                 345                 350         


Ala Pro Ala Pro Trp Val Glu Gln Cys Ile Cys Pro Val Gly Tyr Lys 
        355                 360                 365             


Gly Gln Phe Cys Gln Asp Cys Ala Ser Gly Tyr Lys Arg Asp Ser Ala 
    370                 375                 380                 


Arg Leu Gly Pro Phe Gly Thr Cys Ile Pro Cys Asn Cys Gln Gly Gly 
385                 390                 395                 400 


Gly Ala Cys Asp Pro Asp Thr Gly Asp Cys Tyr Ser Gly Asp Glu Asn 
                405                 410                 415     


Pro Asp Ile Glu Cys Ala Asp Cys Pro Ile Gly Phe Tyr Asn Asp Pro 
            420                 425                 430         


His Asp Pro Arg Ser Cys Lys Pro Cys Pro Cys His Asn Gly Phe Ser 
        435                 440                 445             


Cys Ser Val Met Pro Glu Thr Glu Glu Val Val Cys Asn Asn Cys Pro 
    450                 455                 460                 


Pro Gly Val Thr Gly Ala Arg Cys Glu Leu Cys Ala Asp Gly Tyr Phe 
465                 470                 475                 480 


Gly Asp Pro Phe Gly Glu His Gly Pro Val Arg Pro Cys Gln Pro Cys 
                485                 490                 495     


Gln Cys Asn Asn Asn Val Asp Pro Ser Ala Ser Gly Asn Cys Asp Arg 
            500                 505                 510         


Leu Thr Gly Arg Cys Leu Lys Cys Ile His Asn Thr Ala Gly Ile Tyr 
        515                 520                 525             


Cys Asp Gln Cys Lys Ala Gly Tyr Phe Gly Asp Pro Leu Ala Pro Asn 
    530                 535                 540                 


Pro Ala Asp Lys Cys Arg Ala Cys Asn Cys Asn Pro Met Gly Ser Glu 
545                 550                 555                 560 


Pro Val Gly Cys Arg Ser Asp Gly Thr Cys Val Cys Lys Pro Gly Phe 
                565                 570                 575     


Gly Gly Pro Asn Cys Glu His Gly Ala Phe Ser Cys Pro Ala Cys Tyr 
            580                 585                 590         


Asn Gln Val Lys Ile Gln Met Asp Gln Phe Met Gln Gln Leu Gln Arg 
        595                 600                 605             


Met Glu Ala Leu Ile Ser Lys Ala Gln Gly Gly Asp Gly Val Val Pro 
    610                 615                 620                 


Asp Thr Glu Leu Glu Gly Arg Met Gln Gln Ala Glu Gln Ala Leu Gln 
625                 630                 635                 640 


Asp Ile Leu Arg Asp Ala Gln Ile Ser Glu Gly Ala Ser Arg Ser Leu 
                645                 650                 655     


Gly Leu Gln Leu Ala Lys Val Arg Ser Gln Glu Asn Ser Tyr Gln Ser 
            660                 665                 670         


Arg Leu Asp Asp Leu Lys Met Thr Val Glu Arg Val Arg Ala Leu Gly 
        675                 680                 685             


Ser Gln Tyr Gln Asn Arg Val Arg Asp Thr His Arg Leu Ile Thr Gln 
    690                 695                 700                 


Met Gln Leu Ser Leu Ala Glu Ser Glu Ala Ser Leu Gly Asn Thr Asn 
705                 710                 715                 720 


Ile Pro Ala Ser Asp His Tyr Val Gly Pro Asn Gly Phe Lys Ser Leu 
                725                 730                 735     


Ala Gln Glu Ala Thr Arg Leu Ala Glu Ser His Val Glu Ser Ala Ser 
            740                 745                 750         


Asn Met Glu Gln Leu Thr Arg Glu Thr Glu Asp Tyr Ser Lys Gln Ala 
        755                 760                 765             


Leu Ser Leu Val Arg Lys Ala Leu His Glu Gly Val Gly Ser Gly Ser 
    770                 775                 780                 


Gly Ser Pro Asp Gly Ala Val Val Gln Gly Leu Val Glu Lys Leu Glu 
785                 790                 795                 800 


Lys Thr Lys Ser Leu Ala Gln Gln Leu Thr Arg Glu Ala Thr Gln Ala 
                805                 810                 815     


Glu Ile Glu Ala Asp Arg Ser Tyr Gln His Ser Leu Arg Leu Leu Asp 
            820                 825                 830         


Ser Val Ser Arg Leu Gln Gly Val Ser Asp Gln Ser Phe Gln Val Glu 
        835                 840                 845             


Glu Ala Lys Arg Ile Lys Gln Lys Ala Asp Ser Leu Ser Ser Leu Val 
    850                 855                 860                 


Thr Arg His Met Asp Glu Phe Lys Arg Thr Gln Lys Asn Leu Gly Asn 
865                 870                 875                 880 


Trp Lys Glu Glu Ala Gln Gln Leu Leu Gln Asn Gly Lys Ser Gly Arg 
                885                 890                 895     


Glu Lys Ser Asp Gln Leu Leu Ser Arg Ala Asn Leu Ala Lys Ser Arg 
            900                 905                 910         


Ala Gln Glu Ala Leu Ser Met Gly Asn Ala Thr Phe Tyr Glu Val Glu 
        915                 920                 925             


Ser Ile Leu Lys Asn Leu Arg Glu Phe Asp Leu Gln Val Asp Asn Arg 
    930                 935                 940                 


Lys Ala Glu Ala Glu Glu Ala Met Lys Arg Leu Ser Tyr Ile Ser Gln 
945                 950                 955                 960 


Lys Val Ser Asp Ala Ser Asp Lys Thr Gln Gln Ala Glu Arg Ala Leu 
                965                 970                 975     


Gly Ser Ala Ala Ala Asp Ala Gln Arg Ala Lys Asn Gly Ala Gly Glu 
            980                 985                 990         


Ala Leu Glu Ile Ser Ser Glu Ile  Glu Gln Glu Ile Gly  Ser Leu Asn 
        995                 1000                 1005             


Leu Glu  Ala Asn Val Thr Ala  Asp Gly Ala Leu Ala  Met Glu Lys 
    1010                 1015                 1020             


Gly Leu  Ala Ser Leu Lys Ser  Glu Met Arg Glu Val  Glu Gly Glu 
    1025                 1030                 1035             


Leu Glu  Arg Lys Glu Leu Glu  Phe Asp Thr Asn Met  Asp Ala Val 
    1040                 1045                 1050             


Gln Met  Val Ile Thr Glu Ala  Gln Lys Val Asp Thr  Arg Ala Lys 
    1055                 1060                 1065             


Asn Ala  Gly Val Thr Ile Gln  Asp Thr Leu Asn Thr  Leu Asp Gly 
    1070                 1075                 1080             


Leu Leu  His Leu Met Gly Met  
    1085                 1090 


<210>  803
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  803

Ala Thr Gly Arg Leu Leu Ser Gly Gln Pro Val Cys Arg Gly Gly Thr 
1               5                   10                  15      


Gln Arg Pro Cys Tyr Lys Val Ile Tyr Phe His Asp Thr Ser Arg Arg 
            20                  25                  30          


Leu Asn Phe Glu Glu Ala Lys Glu Ala Cys Arg Arg Asp Gly Gly Gln 
        35                  40                  45              


Leu Val Ser Ile Glu Ser Glu Asp Glu Gln Lys Leu Ile Glu Lys Phe 
    50                  55                  60                  


Ile Glu Asn Leu Leu Pro Ser Asp Gly Asp Phe Trp Ile Gly Leu Arg 
65                  70                  75                  80  


Arg Arg Glu Glu Lys Gln Ser Asn Ser Thr Ala Cys Gln Asp Leu Tyr 
                85                  90                  95      


Ala Trp Thr Asp Gly Ser Ile Ser Gln Phe Arg Asn Trp Tyr Val Asp 
            100                 105                 110         


Glu Pro Ser Cys Gly Ser Glu Val Cys Val Val Met Tyr His Gln Pro 
        115                 120                 125             


Ser Ala Pro Ala Gly Ile Gly Gly Pro Tyr Met Phe Gln Trp Asn Asp 
    130                 135                 140                 


Asp Arg Cys Asn Met Lys Asn Asn Phe Ile Cys Lys Tyr Ser Asp Glu 
145                 150                 155                 160 


Lys Pro Ala Val Pro Ser Arg Glu Ala Glu Gly Glu Glu Thr Glu Leu 
                165                 170                 175     


Thr Thr Pro Val Leu Pro Glu Glu Thr Gln Glu Glu Asp Ala Lys Lys 
            180                 185                 190         


Thr Phe Lys Glu Ser Arg Glu Ala Ala Leu Asn Leu Ala Tyr 
        195                 200                 205     


<210>  804
<211>  767
<212>  PRT
<213>  Homo Sapiens

<400>  804

Ala Val Gly Asp Arg Cys Glu Arg Asn Glu Phe Gln Cys Gln Asp Gly 
1               5                   10                  15      


Lys Cys Ile Ser Tyr Lys Trp Val Cys Asp Gly Ser Ala Glu Cys Gln 
            20                  25                  30          


Asp Gly Ser Asp Glu Ser Gln Glu Thr Cys Leu Ser Val Thr Cys Lys 
        35                  40                  45              


Ser Gly Asp Phe Ser Cys Gly Gly Arg Val Asn Arg Cys Ile Pro Gln 
    50                  55                  60                  


Phe Trp Arg Cys Asp Gly Gln Val Asp Cys Asp Asn Gly Ser Asp Glu 
65                  70                  75                  80  


Gln Gly Cys Pro Pro Lys Thr Cys Ser Gln Asp Glu Phe Arg Cys His 
                85                  90                  95      


Asp Gly Lys Cys Ile Ser Arg Gln Phe Val Cys Asp Ser Asp Arg Asp 
            100                 105                 110         


Cys Leu Asp Gly Ser Asp Glu Ala Ser Cys Pro Val Leu Thr Cys Gly 
        115                 120                 125             


Pro Ala Ser Phe Gln Cys Asn Ser Ser Thr Cys Ile Pro Gln Leu Trp 
    130                 135                 140                 


Ala Cys Asp Asn Asp Pro Asp Cys Glu Asp Gly Ser Asp Glu Trp Pro 
145                 150                 155                 160 


Gln Arg Cys Arg Gly Leu Tyr Val Phe Gln Gly Asp Ser Ser Pro Cys 
                165                 170                 175     


Ser Ala Phe Glu Phe His Cys Leu Ser Gly Glu Cys Ile His Ser Ser 
            180                 185                 190         


Trp Arg Cys Asp Gly Gly Pro Asp Cys Lys Asp Lys Ser Asp Glu Glu 
        195                 200                 205             


Asn Cys Ala Val Ala Thr Cys Arg Pro Asp Glu Phe Gln Cys Ser Asp 
    210                 215                 220                 


Gly Asn Cys Ile His Gly Ser Arg Gln Cys Asp Arg Glu Tyr Asp Cys 
225                 230                 235                 240 


Lys Asp Met Ser Asp Glu Val Gly Cys Val Asn Val Thr Leu Cys Glu 
                245                 250                 255     


Gly Pro Asn Lys Phe Lys Cys His Ser Gly Glu Cys Ile Thr Leu Asp 
            260                 265                 270         


Lys Val Cys Asn Met Ala Arg Asp Cys Arg Asp Trp Ser Asp Glu Pro 
        275                 280                 285             


Ile Lys Glu Cys Gly Thr Asn Glu Cys Leu Asp Asn Asn Gly Gly Cys 
    290                 295                 300                 


Ser His Val Cys Asn Asp Leu Lys Ile Gly Tyr Glu Cys Leu Cys Pro 
305                 310                 315                 320 


Asp Gly Phe Gln Leu Val Ala Gln Arg Arg Cys Glu Asp Ile Asp Glu 
                325                 330                 335     


Cys Gln Asp Pro Asp Thr Cys Ser Gln Leu Cys Val Asn Leu Glu Gly 
            340                 345                 350         


Gly Tyr Lys Cys Gln Cys Glu Glu Gly Phe Gln Leu Asp Pro His Thr 
        355                 360                 365             


Lys Ala Cys Lys Ala Val Gly Ser Ile Ala Tyr Leu Phe Phe Thr Asn 
    370                 375                 380                 


Arg His Glu Val Arg Lys Met Thr Leu Asp Arg Ser Glu Tyr Thr Ser 
385                 390                 395                 400 


Leu Ile Pro Asn Leu Arg Asn Val Val Ala Leu Asp Thr Glu Val Ala 
                405                 410                 415     


Ser Asn Arg Ile Tyr Trp Ser Asp Leu Ser Gln Arg Met Ile Cys Ser 
            420                 425                 430         


Thr Gln Leu Asp Arg Ala His Gly Val Ser Ser Tyr Asp Thr Val Ile 
        435                 440                 445             


Ser Arg Asp Ile Gln Ala Pro Asp Gly Leu Ala Val Asp Trp Ile His 
    450                 455                 460                 


Ser Asn Ile Tyr Trp Thr Asp Ser Val Leu Gly Thr Val Ser Val Ala 
465                 470                 475                 480 


Asp Thr Lys Gly Val Lys Arg Lys Thr Leu Phe Arg Glu Asn Gly Ser 
                485                 490                 495     


Lys Pro Arg Ala Ile Val Val Asp Pro Val His Gly Phe Met Tyr Trp 
            500                 505                 510         


Thr Asp Trp Gly Thr Pro Ala Lys Ile Lys Lys Gly Gly Leu Asn Gly 
        515                 520                 525             


Val Asp Ile Tyr Ser Leu Val Thr Glu Asn Ile Gln Trp Pro Asn Gly 
    530                 535                 540                 


Ile Thr Leu Asp Leu Leu Ser Gly Arg Leu Tyr Trp Val Asp Ser Lys 
545                 550                 555                 560 


Leu His Ser Ile Ser Ser Ile Asp Val Asn Gly Gly Asn Arg Lys Thr 
                565                 570                 575     


Ile Leu Glu Asp Glu Lys Arg Leu Ala His Pro Phe Ser Leu Ala Val 
            580                 585                 590         


Phe Glu Asp Lys Val Phe Trp Thr Asp Ile Ile Asn Glu Ala Ile Phe 
        595                 600                 605             


Ser Ala Asn Arg Leu Thr Gly Ser Asp Val Asn Leu Leu Ala Glu Asn 
    610                 615                 620                 


Leu Leu Ser Pro Glu Asp Met Val Leu Phe His Asn Leu Thr Gln Pro 
625                 630                 635                 640 


Arg Gly Val Asn Trp Cys Glu Arg Thr Thr Leu Ser Asn Gly Gly Cys 
                645                 650                 655     


Gln Tyr Leu Cys Leu Pro Ala Pro Gln Ile Asn Pro His Ser Pro Lys 
            660                 665                 670         


Phe Thr Cys Ala Cys Pro Asp Gly Met Leu Leu Ala Arg Asp Met Arg 
        675                 680                 685             


Ser Cys Leu Thr Glu Ala Glu Ala Ala Val Ala Thr Gln Glu Thr Ser 
    690                 695                 700                 


Thr Val Arg Leu Lys Val Ser Ser Thr Ala Val Arg Thr Gln His Thr 
705                 710                 715                 720 


Thr Thr Arg Pro Val Pro Asp Thr Ser Arg Leu Pro Gly Ala Thr Pro 
                725                 730                 735     


Gly Leu Thr Thr Val Glu Ile Val Thr Met Ser His Gln Ala Leu Gly 
            740                 745                 750         


Asp Val Ala Gly Arg Gly Asn Glu Lys Lys Pro Ser Ser Val Arg 
        755                 760                 765         


<210>  805
<211>  613
<212>  PRT
<213>  Homo Sapiens

<400>  805

Phe Asn Leu Ser Tyr Pro Ile Thr Pro Trp Arg Phe Lys Leu Ser Cys 
1               5                   10                  15      


Met Pro Pro Asn Ser Thr Tyr Asp Tyr Phe Leu Leu Pro Ala Gly Leu 
            20                  25                  30          


Ser Lys Asn Thr Ser Asn Ser Asn Gly His Tyr Glu Thr Ala Val Glu 
        35                  40                  45              


Pro Lys Phe Asn Ser Ser Gly Thr His Phe Ser Asn Leu Ser Lys Thr 
    50                  55                  60                  


Thr Phe His Cys Cys Phe Arg Ser Glu Gln Asp Arg Asn Cys Ser Leu 
65                  70                  75                  80  


Cys Ala Asp Asn Ile Glu Gly Lys Thr Phe Val Ser Thr Val Asn Ser 
                85                  90                  95      


Leu Val Phe Gln Gln Ile Asp Ala Asn Trp Asn Ile Gln Cys Trp Leu 
            100                 105                 110         


Lys Gly Asp Leu Lys Leu Phe Ile Cys Tyr Val Glu Ser Leu Phe Lys 
        115                 120                 125             


Asn Leu Phe Arg Asn Tyr Asn Tyr Lys Val His Leu Leu Tyr Val Leu 
    130                 135                 140                 


Pro Glu Val Leu Glu Asp Ser Pro Leu Val Pro Gln Lys Gly Ser Phe 
145                 150                 155                 160 


Gln Met Val His Cys Asn Cys Ser Val His Glu Cys Cys Glu Cys Leu 
                165                 170                 175     


Val Pro Val Pro Thr Ala Lys Leu Asn Asp Thr Leu Leu Met Cys Leu 
            180                 185                 190         


Lys Ile Thr Ser Gly Gly Val Ile Phe Gln Ser Pro Leu Met Ser Val 
        195                 200                 205             


Gln Pro Ile Asn Met Val Lys Pro Asp Pro Pro Leu Gly Leu His Met 
    210                 215                 220                 


Glu Ile Thr Asp Asp Gly Asn Leu Lys Ile Ser Trp Ser Ser Pro Pro 
225                 230                 235                 240 


Leu Val Pro Phe Pro Leu Gln Tyr Gln Val Lys Tyr Ser Glu Asn Ser 
                245                 250                 255     


Thr Thr Val Ile Arg Glu Ala Asp Lys Ile Val Ser Ala Thr Ser Leu 
            260                 265                 270         


Leu Val Asp Ser Ile Leu Pro Gly Ser Ser Tyr Glu Val Gln Val Arg 
        275                 280                 285             


Gly Lys Arg Leu Asp Gly Pro Gly Ile Trp Ser Asp Trp Ser Thr Pro 
    290                 295                 300                 


Arg Val Phe Thr Thr Gln Asp Val Ile Tyr Phe Pro Pro Lys Ile Leu 
305                 310                 315                 320 


Thr Ser Val Gly Ser Asn Val Ser Phe His Cys Ile Tyr Lys Lys Glu 
                325                 330                 335     


Asn Lys Ile Val Pro Ser Lys Glu Ile Val Trp Trp Met Asn Leu Ala 
            340                 345                 350         


Glu Lys Ile Pro Gln Ser Gln Tyr Asp Val Val Ser Asp Asn Val Ser 
        355                 360                 365             


Lys Val Thr Phe Phe Asn Leu Asn Glu Thr Lys Pro Arg Gly Lys Phe 
    370                 375                 380                 


Thr Tyr Asp Ala Val Tyr Cys Cys Asn Glu His Glu Cys His His Arg 
385                 390                 395                 400 


Tyr Ala Glu Leu Tyr Val Ile Asp Val Asn Ile Asn Ile Ser Cys Glu 
                405                 410                 415     


Thr Asp Gly Tyr Leu Thr Lys Met Thr Cys Arg Trp Ser Thr Ser Thr 
            420                 425                 430         


Ile Gln Ser Leu Ala Glu Ser Thr Leu Gln Leu Arg Tyr His Arg Ser 
        435                 440                 445             


Ser Leu Tyr Cys Ser Asp Ile Pro Ser Ile His Pro Ile Ser Glu Pro 
    450                 455                 460                 


Lys Asp Cys Tyr Leu Gln Ser Asp Gly Phe Tyr Glu Cys Ile Phe Gln 
465                 470                 475                 480 


Pro Ile Phe Leu Leu Ser Gly Tyr Thr Met Trp Ile Arg Ile Asn His 
                485                 490                 495     


Ser Leu Gly Ser Leu Asp Ser Pro Pro Thr Cys Val Leu Pro Asp Ser 
            500                 505                 510         


Val Val Lys Pro Leu Pro Pro Ser Ser Val Lys Ala Glu Ile Thr Ile 
        515                 520                 525             


Asn Ile Gly Leu Leu Lys Ile Ser Trp Glu Lys Pro Val Phe Pro Glu 
    530                 535                 540                 


Asn Asn Leu Gln Phe Gln Ile Arg Tyr Gly Leu Ser Gly Lys Glu Val 
545                 550                 555                 560 


Gln Trp Lys Met Tyr Glu Val Tyr Asp Ala Lys Ser Lys Ser Val Ser 
                565                 570                 575     


Leu Pro Val Pro Asp Leu Cys Ala Val Tyr Ala Val Gln Val Arg Cys 
            580                 585                 590         


Lys Arg Leu Asp Gly Leu Gly Tyr Trp Ser Asn Trp Ser Asn Pro Ala 
        595                 600                 605             


Tyr Thr Val Val Met 
    610             


<210>  806
<211>  523
<212>  PRT
<213>  Homo Sapiens

<400>  806

Lys Lys Pro Ala Lys Pro Lys Cys Pro Ala Val Cys Thr Cys Thr Lys 
1               5                   10                  15      


Asp Asn Ala Leu Cys Glu Asn Ala Arg Ser Ile Pro Arg Thr Val Pro 
            20                  25                  30          


Pro Asp Val Ile Ser Leu Ser Phe Val Arg Ser Gly Phe Thr Glu Ile 
        35                  40                  45              


Ser Glu Gly Ser Phe Leu Phe Thr Pro Ser Leu Gln Leu Leu Leu Phe 
    50                  55                  60                  


Thr Ser Asn Ser Phe Asp Val Ile Ser Asp Asp Ala Phe Ile Gly Leu 
65                  70                  75                  80  


Pro His Leu Glu Tyr Leu Phe Ile Glu Asn Asn Asn Ile Lys Ser Ile 
                85                  90                  95      


Ser Arg His Thr Phe Arg Gly Leu Lys Ser Leu Ile His Leu Ser Leu 
            100                 105                 110         


Ala Asn Asn Asn Leu Gln Thr Leu Pro Lys Asp Ile Phe Lys Gly Leu 
        115                 120                 125             


Asp Ser Leu Thr Asn Val Asp Leu Arg Gly Asn Ser Phe Asn Cys Asp 
    130                 135                 140                 


Cys Lys Leu Lys Trp Leu Val Glu Trp Leu Gly His Thr Asn Ala Thr 
145                 150                 155                 160 


Val Glu Asp Ile Tyr Cys Glu Gly Pro Pro Glu Tyr Lys Lys Arg Lys 
                165                 170                 175     


Ile Asn Ser Leu Ser Ser Lys Asp Phe Asp Cys Ile Ile Thr Glu Phe 
            180                 185                 190         


Ala Lys Ser Gln Asp Leu Pro Tyr Gln Ser Leu Ser Ile Asp Thr Phe 
        195                 200                 205             


Ser Tyr Leu Asn Asp Glu Tyr Val Val Ile Ala Gln Pro Phe Thr Gly 
    210                 215                 220                 


Lys Cys Ile Phe Leu Glu Trp Asp His Val Glu Lys Thr Phe Arg Asn 
225                 230                 235                 240 


Tyr Asp Asn Ile Thr Gly Thr Ser Thr Val Val Cys Lys Pro Ile Val 
                245                 250                 255     


Ile Glu Thr Gln Leu Tyr Val Ile Val Ala Gln Leu Phe Gly Gly Ser 
            260                 265                 270         


His Ile Tyr Lys Arg Asp Ser Phe Ala Asn Lys Phe Ile Lys Ile Gln 
        275                 280                 285             


Asp Ile Glu Ile Leu Lys Ile Arg Lys Pro Asn Asp Ile Glu Thr Phe 
    290                 295                 300                 


Lys Ile Glu Asn Asn Trp Tyr Phe Val Val Ala Asp Ser Ser Lys Ala 
305                 310                 315                 320 


Gly Phe Thr Thr Ile Tyr Lys Trp Asn Gly Asn Gly Phe Tyr Ser His 
                325                 330                 335     


Gln Ser Leu His Ala Trp Tyr Arg Asp Thr Asp Val Glu Tyr Leu Glu 
            340                 345                 350         


Ile Val Arg Thr Pro Gln Thr Leu Arg Thr Pro His Leu Ile Leu Ser 
        355                 360                 365             


Ser Ser Ser Gln Arg Pro Val Ile Tyr Gln Trp Asn Lys Ala Thr Gln 
    370                 375                 380                 


Leu Phe Thr Asn Gln Thr Asp Ile Pro Asn Met Glu Asp Val Tyr Ala 
385                 390                 395                 400 


Val Lys His Phe Ser Val Lys Gly Asp Val Tyr Ile Cys Leu Thr Arg 
                405                 410                 415     


Phe Ile Gly Asp Ser Lys Val Met Lys Trp Gly Gly Ser Ser Phe Gln 
            420                 425                 430         


Asp Ile Gln Arg Met Pro Ser Arg Gly Ser Met Val Phe Gln Pro Leu 
        435                 440                 445             


Gln Ile Asn Asn Tyr Gln Tyr Ala Ile Leu Gly Ser Asp Tyr Ser Phe 
    450                 455                 460                 


Thr Gln Val Tyr Asn Trp Asp Ala Glu Lys Ala Lys Phe Val Lys Phe 
465                 470                 475                 480 


Gln Glu Leu Asn Val Gln Ala Pro Arg Ser Phe Thr His Val Ser Ile 
                485                 490                 495     


Asn Lys Arg Asn Phe Leu Phe Ala Ser Ser Phe Lys Gly Asn Thr Gln 
            500                 505                 510         


Ile Tyr Lys His Val Ile Val Asp Leu Ser Ala 
        515                 520             


<210>  807
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  807

Gln Val Arg Arg Leu Ala Arg Cys Pro Ala Thr Cys Ser Cys Thr Lys 
1               5                   10                  15      


Glu Ser Ile Ile Cys Val Gly Ser Ser Trp Val Pro Arg Ile Val Pro 
            20                  25                  30          


Gly Asp Ile Ser Ser Leu Ser Leu Val Asn Gly Thr Phe Ser Glu Ile 
        35                  40                  45              


Lys Asp Arg Met Phe Ser His Leu Pro Ser Leu Gln Leu Leu Leu Leu 
    50                  55                  60                  


Asn Ser Asn Ser Phe Thr Ile Ile Arg Asp Asp Ala Phe Ala Gly Leu 
65                  70                  75                  80  


Phe His Leu Glu Tyr Leu Phe Ile Glu Gly Asn Lys Ile Glu Thr Ile 
                85                  90                  95      


Ser Arg Asn Ala Phe Arg Gly Leu Arg Asp Leu Thr His Leu Ser Leu 
            100                 105                 110         


Ala Asn Asn His Ile Lys Ala Leu Pro Arg Asp Val Phe Ser Asp Leu 
        115                 120                 125             


Asp Ser Leu Ile Glu Leu Asp Leu Arg Gly Asn Lys Phe Glu Cys Asp 
    130                 135                 140                 


Cys Lys Ala Lys Trp Leu Tyr Leu Trp Leu Lys Met Thr Asn Ser Thr 
145                 150                 155                 160 


Val Ser Asp Val Leu Cys Ile Gly Pro Pro Glu Tyr Gln Glu Lys Lys 
                165                 170                 175     


Leu Asn Asp Val Thr Ser Phe Asp Tyr Glu Cys Thr Thr Thr Asp Phe 
            180                 185                 190         


Val Val His Gln Thr Leu Pro Tyr Gln Ser Val Ser Val Asp Thr Phe 
        195                 200                 205             


Asn Ser Lys Asn Asp Val Tyr Val Ala Ile Ala Gln Pro Ser Met Glu 
    210                 215                 220                 


Asn Cys Met Val Leu Glu Trp Asp His Ile Glu Met Asn Phe Arg Ser 
225                 230                 235                 240 


Tyr Asp Asn Ile Thr Gly Gln Ser Ile Val Gly Cys Lys Ala Ile Leu 
                245                 250                 255     


Ile Asp Asp Gln Val Phe Val Val Val Ala Gln Leu Phe Gly Gly Ser 
            260                 265                 270         


His Ile Tyr Lys Tyr Asp Glu Ser Trp Thr Lys Phe Val Lys Phe Gln 
        275                 280                 285             


Asp Ile Glu Val Ser Arg Ile Ser Lys Pro Asn Asp Ile Glu Leu Phe 
    290                 295                 300                 


Gln Ile Asp Asp Glu Thr Phe Phe Val Ile Ala Asp Ser Ser Lys Ala 
305                 310                 315                 320 


Gly Leu Ser Thr Val Tyr Lys Trp Asn Ser Lys Gly Phe Tyr Ser Tyr 
                325                 330                 335     


Gln Ser Leu His Glu Trp Phe Arg Asp Thr Asp Ala Glu Phe Val Asp 
            340                 345                 350         


Ile Asp Gly Lys Ser His Leu Ile Leu Ser Ser Arg Ser Gln Val Pro 
        355                 360                 365             


Ile Ile Leu Gln Trp Asn Lys Ser Ser Lys Lys Phe Val Pro His Gly 
    370                 375                 380                 


Asp Ile Pro Asn Met Glu Asp Val Leu Ala Val Lys Ser Phe Arg Met 
385                 390                 395                 400 


Gln Asn Thr Leu Tyr Leu Ser Leu Thr Arg Phe Ile Gly Asp Ser Arg 
                405                 410                 415     


Val Met Arg Trp Asn Ser Lys Gln Phe Val Glu Ile Gln Ala Leu Pro 
            420                 425                 430         


Ser Arg Gly Ala Met Thr Leu Gln Pro Phe Ser Phe Lys Asp Asn His 
        435                 440                 445             


Tyr Leu Ala Leu Gly Ser Asp Tyr Thr Phe Ser Gln Ile Tyr Gln Trp 
    450                 455                 460                 


Asp Lys Glu Lys Gln Leu Phe Lys Lys Phe Lys Glu Ile Tyr Val Gln 
465                 470                 475                 480 


Ala Pro Arg Ser Phe Thr Ala Val Ser Thr Asp Arg Arg Asp Phe Phe 
                485                 490                 495     


Phe Ala Ser Ser Phe Lys Gly Lys Thr Lys Ile Phe Glu His Ile Ile 
            500                 505                 510         


Val Asp Leu Ser Leu 
        515         


<210>  808
<211>  518
<212>  PRT
<213>  Homo Sapiens

<400>  808

Lys Arg Pro Pro Lys Thr Pro Pro Cys Pro Pro Ser Cys Ser Cys Thr 
1               5                   10                  15      


Arg Asp Thr Ala Phe Cys Val Asp Ser Lys Ala Val Pro Arg Asn Leu 
            20                  25                  30          


Pro Ser Glu Val Ile Ser Leu Thr Leu Val Asn Ala Ala Phe Ser Glu 
        35                  40                  45              


Ile Gln Asp Gly Ala Phe Ser His Leu Pro Leu Leu Gln Phe Leu Leu 
    50                  55                  60                  


Leu Asn Ser Asn Lys Phe Thr Leu Ile Gly Asp Asn Ala Phe Thr Gly 
65                  70                  75                  80  


Leu Ser His Leu Gln Tyr Leu Phe Ile Glu Asn Asn Asp Ile Trp Ala 
                85                  90                  95      


Leu Ser Lys Phe Thr Phe Arg Gly Leu Lys Ser Leu Thr His Leu Ser 
            100                 105                 110         


Leu Ala Asn Asn Asn Leu Gln Thr Leu Pro Arg Asp Ile Phe Arg Pro 
        115                 120                 125             


Leu Asp Ile Leu Asn Asp Leu Asp Leu Arg Gly Asn Ser Leu Asn Cys 
    130                 135                 140                 


Asp Cys Lys Val Lys Trp Leu Val Glu Trp Leu Ala His Thr Asn Thr 
145                 150                 155                 160 


Thr Val Ala Pro Ile Tyr Cys Ala Ser Pro Pro Arg Phe Gln Glu His 
                165                 170                 175     


Lys Val Gln Asp Leu Pro Leu Arg Glu Phe Asp Cys Ile Thr Thr Asp 
            180                 185                 190         


Phe Val Leu Tyr Gln Thr Leu Ala Phe Pro Ala Val Ser Ala Glu Pro 
        195                 200                 205             


Phe Leu Tyr Ser Ser Asp Leu Tyr Leu Ala Leu Ala Gln Pro Gly Val 
    210                 215                 220                 


Ser Ala Cys Thr Ile Leu Lys Trp Asp Tyr Val Glu Arg Gln Leu Arg 
225                 230                 235                 240 


Asp Tyr Asp Arg Ile Pro Ala Pro Ser Ala Val His Cys Lys Pro Met 
                245                 250                 255     


Val Val Asp Ser Gln Leu Tyr Val Val Val Ala Gln Leu Phe Gly Gly 
            260                 265                 270         


Ser Tyr Ile Tyr His Trp Asp Pro Asn Thr Thr Arg Phe Thr Arg Leu 
        275                 280                 285             


Gln Asp Ile Asp Pro Gln Arg Val Arg Lys Pro Asn Asp Leu Glu Ala 
    290                 295                 300                 


Phe Arg Ile Asp Gly Asp Trp Tyr Phe Ala Val Ala Asp Ser Ser Lys 
305                 310                 315                 320 


Ala Gly Ala Thr Ser Leu Tyr Arg Trp His Gln Asn Gly Phe Tyr Ser 
                325                 330                 335     


His Gln Ala Leu His Pro Trp His Arg Asp Thr Asp Leu Glu Phe Val 
            340                 345                 350         


Asp Gly Glu Gly Lys Pro Arg Leu Ile Val Ser Ser Ser Ser Gln Ala 
        355                 360                 365             


Pro Val Ile Tyr Gln Trp Ser Arg Thr Gln Lys Gln Phe Val Ala Gln 
    370                 375                 380                 


Gly Glu Val Thr Gln Val Pro Asp Ala Gln Ala Val Lys His Phe Arg 
385                 390                 395                 400 


Ala Gly Arg Asp Ser Tyr Leu Cys Leu Ser Arg Tyr Ile Gly Asp Ser 
                405                 410                 415     


Lys Ile Leu Arg Trp Glu Gly Thr Arg Phe Ser Glu Val Gln Ala Leu 
            420                 425                 430         


Pro Ser Arg Gly Ser Leu Ala Leu Gln Pro Phe Leu Val Gly Gly Arg 
        435                 440                 445             


Arg Tyr Leu Ala Leu Gly Ser Asp Phe Ser Phe Thr Gln Ile Tyr Gln 
    450                 455                 460                 


Trp Asp Glu Gly Arg Gln Lys Phe Val Arg Phe Gln Glu Leu Ala Val 
465                 470                 475                 480 


Gln Ala Pro Arg Ala Phe Cys Tyr Met Pro Ala Gly Asp Ala Gln Leu 
                485                 490                 495     


Leu Leu Ala Pro Ser Phe Lys Gly Gln Thr Leu Val Tyr Arg His Ile 
            500                 505                 510         


Val Val Asp Leu Ser Ala 
        515             


<210>  809
<211>  518
<212>  PRT
<213>  Homo Sapiens

<400>  809

Trp Arg Pro Pro Lys Gly Lys Cys Pro Leu Arg Cys Ser Cys Ser Lys 
1               5                   10                  15      


Asp Ser Ala Leu Cys Glu Gly Ser Pro Asp Leu Pro Val Ser Phe Ser 
            20                  25                  30          


Pro Thr Leu Leu Ser Leu Ser Leu Val Arg Thr Gly Val Thr Gln Leu 
        35                  40                  45              


Lys Ala Gly Ser Phe Leu Arg Ile Pro Ser Leu His Leu Leu Leu Phe 
    50                  55                  60                  


Thr Ser Asn Ser Phe Ser Val Ile Glu Asp Asp Ala Phe Ala Gly Leu 
65                  70                  75                  80  


Ser His Leu Gln Tyr Leu Phe Ile Glu Asp Asn Glu Ile Gly Ser Ile 
                85                  90                  95      


Ser Lys Asn Ala Leu Arg Gly Leu Arg Ser Leu Thr His Leu Ser Leu 
            100                 105                 110         


Ala Asn Asn His Leu Glu Thr Leu Pro Arg Phe Leu Phe Arg Gly Leu 
        115                 120                 125             


Asp Thr Leu Thr His Val Asp Leu Arg Gly Asn Pro Phe Gln Cys Asp 
    130                 135                 140                 


Cys Arg Val Leu Trp Leu Leu Gln Trp Met Pro Thr Val Asn Ala Ser 
145                 150                 155                 160 


Val Gly Thr Gly Ala Cys Ala Gly Pro Ala Ser Leu Ser His Met Gln 
                165                 170                 175     


Leu His His Leu Asp Pro Lys Thr Phe Lys Cys Arg Ala Ile Glu Leu 
            180                 185                 190         


Ser Trp Phe Gln Thr Val Gly Glu Ser Ala Leu Ser Val Glu Pro Phe 
        195                 200                 205             


Ser Tyr Gln Gly Glu Pro His Ile Val Leu Ala Gln Pro Phe Ala Gly 
    210                 215                 220                 


Arg Cys Leu Ile Leu Ser Trp Asp Tyr Ser Leu Gln Arg Phe Arg Pro 
225                 230                 235                 240 


Glu Glu Glu Leu Pro Ala Ala Ser Val Val Ser Cys Lys Pro Leu Val 
                245                 250                 255     


Leu Gly Pro Ser Leu Phe Val Leu Ala Ala Arg Leu Trp Gly Gly Ser 
            260                 265                 270         


Gln Leu Trp Ala Arg Pro Ser Pro Gly Leu Arg Leu Ala Pro Thr Gln 
        275                 280                 285             


Thr Leu Ala Pro Arg Arg Leu Leu Arg Pro Asn Asp Ala Glu Leu Leu 
    290                 295                 300                 


Trp Leu Glu Gly Gln Pro Cys Phe Val Val Ala Asp Ala Ser Lys Ala 
305                 310                 315                 320 


Gly Ser Thr Thr Leu Leu Cys Arg Asp Gly Pro Gly Phe Tyr Pro His 
                325                 330                 335     


Gln Ser Leu His Ala Trp His Arg Asp Thr Asp Ala Glu Ala Leu Glu 
            340                 345                 350         


Leu Asp Gly Arg Pro His Leu Leu Leu Ala Ser Ala Ser Gln Arg Pro 
        355                 360                 365             


Val Leu Phe His Trp Thr Gly Gly Arg Phe Glu Arg Arg Thr Asp Ile 
    370                 375                 380                 


Pro Glu Ala Glu Asp Val Tyr Ala Thr Arg His Phe Gln Ala Gly Gly 
385                 390                 395                 400 


Asp Val Phe Leu Cys Leu Thr Arg Tyr Ile Gly Asp Ser Met Val Met 
                405                 410                 415     


Arg Trp Asp Gly Ser Met Phe Arg Leu Leu Gln Gln Leu Pro Ser Arg 
            420                 425                 430         


Gly Ala His Val Phe Gln Pro Leu Leu Ile Ala Arg Asp Gln Leu Ala 
        435                 440                 445             


Ile Leu Gly Ser Asp Phe Ala Phe Ser Gln Val Leu Arg Leu Glu Pro 
    450                 455                 460                 


Asp Lys Gly Leu Leu Glu Pro Leu Gln Glu Leu Gly Pro Pro Ala Leu 
465                 470                 475                 480 


Val Ala Pro Arg Ala Phe Ala His Ile Thr Met Ala Gly Arg Arg Phe 
                485                 490                 495     


Leu Phe Ala Ala Cys Phe Lys Gly Pro Thr Gln Ile Tyr Gln His His 
            500                 505                 510         


Glu Ile Asp Leu Ser Ala 
        515             


<210>  810
<211>  520
<212>  PRT
<213>  Homo Sapiens

<400>  810

Ala Pro Pro Leu Cys Ala Ala Pro Cys Ser Cys Asp Gly Asp Arg Arg 
1               5                   10                  15      


Val Asp Cys Ser Gly Lys Gly Leu Thr Ala Val Pro Glu Gly Leu Ser 
            20                  25                  30          


Ala Phe Thr Gln Ala Leu Asp Ile Ser Met Asn Asn Ile Thr Gln Leu 
        35                  40                  45              


Pro Glu Asp Ala Phe Lys Asn Phe Pro Phe Leu Glu Glu Leu Gln Leu 
    50                  55                  60                  


Ala Gly Asn Asp Leu Ser Phe Ile His Pro Lys Ala Leu Ser Gly Leu 
65                  70                  75                  80  


Lys Glu Leu Lys Val Leu Thr Leu Gln Asn Asn Gln Leu Lys Thr Val 
                85                  90                  95      


Pro Ser Glu Ala Ile Arg Gly Leu Ser Ala Leu Gln Ser Leu Arg Leu 
            100                 105                 110         


Asp Ala Asn His Ile Thr Ser Val Pro Glu Asp Ser Phe Glu Gly Leu 
        115                 120                 125             


Val Gln Leu Arg His Leu Trp Leu Asp Asp Asn Ser Leu Thr Glu Val 
    130                 135                 140                 


Pro Val His Pro Leu Ser Asn Leu Pro Thr Leu Gln Ala Leu Thr Leu 
145                 150                 155                 160 


Ala Leu Asn Lys Ile Ser Ser Ile Pro Asp Phe Ala Phe Thr Asn Leu 
                165                 170                 175     


Ser Ser Leu Val Val Leu His Leu His Asn Asn Lys Ile Arg Gly Leu 
            180                 185                 190         


Ser Gln His Cys Phe Asp Gly Leu Asp Asn Leu Glu Thr Leu Asp Leu 
        195                 200                 205             


Ser Tyr Asn Asn Leu Gly Glu Phe Pro Gln Ala Ile Lys Ala Arg Pro 
    210                 215                 220                 


Ser Leu Lys Glu Leu Gly Phe His Ser Asn Ser Ile Ser Val Ile Pro 
225                 230                 235                 240 


Asp Gly Ala Phe Asp Gly Asn Pro Leu Leu Arg Thr Ile His Leu Tyr 
                245                 250                 255     


Asp Asn Pro Leu Ser Phe Val Gly Asn Ser Ala Ser His Asn Leu Ser 
            260                 265                 270         


Asp Leu His Ser Leu Val Ile Arg Gly Ala Ser Met Val Gln Gln Phe 
        275                 280                 285             


Pro Asn Leu Thr Gly Thr Val His Leu Glu Ser Leu Thr Leu Thr Gly 
    290                 295                 300                 


Thr Lys Ile Ser Ser Ile Pro Asn Asn Leu Cys Gln Glu Gln Lys Met 
305                 310                 315                 320 


Leu Arg Thr Leu Asp Leu Ser Tyr Asn Asn Ile Arg Asp Leu Pro Ser 
                325                 330                 335     


Phe Asn Gly Cys His Ala Leu Glu Glu Ile Ser Leu Gln Arg Asn Gln 
            340                 345                 350         


Ile Tyr Gln Ile Lys Glu Gly Thr Phe Gln Gly Leu Ile Ser Leu Arg 
        355                 360                 365             


Ile Leu Asp Leu Ser Arg Asn Leu Ile His Glu Ile His Ser Arg Ala 
    370                 375                 380                 


Phe Ala Thr Leu Gly Pro Ile Thr Asn Leu Asp Val Ser Phe Asn Glu 
385                 390                 395                 400 


Leu Thr Ser Phe Pro Thr Glu Gly Pro Asn Gly Leu Asn Gln Leu Lys 
                405                 410                 415     


Leu Val Gly Asn Phe Lys Leu Lys Glu Ala Leu Ala Ala Lys Asp Phe 
            420                 425                 430         


Val Asn Leu Arg Ser Leu Ser Val Pro Tyr Ala Tyr Gln Cys Cys Ala 
        435                 440                 445             


Phe Trp Gly Cys Asp Ser Tyr Ala Asn Leu Asn Thr Glu Asp Asn Ser 
    450                 455                 460                 


Leu Gln Asp His Ser Val Ala Gln Glu Lys Gly Thr Ala Asp Ala Ala 
465                 470                 475                 480 


Asn Val Thr Ser Thr Leu Glu Asn Glu Glu His Ser Gln Ile Ile Ile 
                485                 490                 495     


His Cys Thr Pro Ser Thr Gly Ala Phe Lys Pro Cys Glu Tyr Leu Leu 
            500                 505                 510         


Gly Ser Trp Met Ile Arg Leu Thr 
        515                 520 


<210>  811
<211>  540
<212>  PRT
<213>  Homo Sapiens

<400>  811

Gly Ser Ser Pro Arg Ser Gly Val Leu Leu Arg Gly Cys Pro Thr His 
1               5                   10                  15      


Cys His Cys Glu Pro Asp Gly Arg Met Leu Leu Arg Val Asp Cys Ser 
            20                  25                  30          


Asp Leu Gly Leu Ser Glu Leu Pro Ser Asn Leu Ser Val Phe Thr Ser 
        35                  40                  45              


Tyr Leu Asp Leu Ser Met Asn Asn Ile Ser Gln Leu Leu Pro Asn Pro 
    50                  55                  60                  


Leu Pro Ser Leu Arg Phe Leu Glu Glu Leu Arg Leu Ala Gly Asn Ala 
65                  70                  75                  80  


Leu Thr Tyr Ile Pro Lys Gly Ala Phe Thr Gly Leu Tyr Ser Leu Lys 
                85                  90                  95      


Val Leu Met Leu Gln Asn Asn Gln Leu Arg His Val Pro Thr Glu Ala 
            100                 105                 110         


Leu Gln Asn Leu Arg Ser Leu Gln Ser Leu Arg Leu Asp Ala Asn His 
        115                 120                 125             


Ile Ser Tyr Val Pro Pro Ser Cys Phe Ser Gly Leu His Ser Leu Arg 
    130                 135                 140                 


His Leu Trp Leu Asp Asp Asn Ala Leu Thr Glu Ile Pro Val Gln Ala 
145                 150                 155                 160 


Phe Arg Ser Leu Ser Ala Leu Gln Ala Met Thr Leu Ala Leu Asn Lys 
                165                 170                 175     


Ile His His Ile Pro Asp Tyr Ala Phe Gly Asn Leu Ser Ser Leu Val 
            180                 185                 190         


Val Leu His Leu His Asn Asn Arg Ile His Ser Leu Gly Lys Lys Cys 
        195                 200                 205             


Phe Asp Gly Leu His Ser Leu Glu Thr Leu Asp Leu Asn Tyr Asn Asn 
    210                 215                 220                 


Leu Asp Glu Phe Pro Thr Ala Ile Arg Thr Leu Ser Asn Leu Lys Glu 
225                 230                 235                 240 


Leu Gly Phe His Ser Asn Asn Ile Arg Ser Ile Pro Glu Lys Ala Phe 
                245                 250                 255     


Val Gly Asn Pro Ser Leu Ile Thr Ile His Phe Tyr Asp Asn Pro Ile 
            260                 265                 270         


Gln Phe Val Gly Arg Ser Ala Phe Gln His Leu Pro Glu Leu Arg Thr 
        275                 280                 285             


Leu Thr Leu Asn Gly Ala Ser Gln Ile Thr Glu Phe Pro Asp Leu Thr 
    290                 295                 300                 


Gly Thr Ala Asn Leu Glu Ser Leu Thr Leu Thr Gly Ala Gln Ile Ser 
305                 310                 315                 320 


Ser Leu Pro Gln Thr Val Cys Asn Gln Leu Pro Asn Leu Gln Val Leu 
                325                 330                 335     


Asp Leu Ser Tyr Asn Leu Leu Glu Asp Leu Pro Ser Phe Ser Val Cys 
            340                 345                 350         


Gln Lys Leu Gln Lys Ile Asp Leu Arg His Asn Glu Ile Tyr Glu Ile 
        355                 360                 365             


Lys Val Asp Thr Phe Gln Gln Leu Leu Ser Leu Arg Ser Leu Asn Leu 
    370                 375                 380                 


Ala Trp Asn Lys Ile Ala Ile Ile His Pro Asn Ala Phe Ser Thr Leu 
385                 390                 395                 400 


Pro Ser Leu Ile Lys Leu Asp Leu Ser Ser Asn Leu Leu Ser Ser Phe 
                405                 410                 415     


Pro Ile Thr Gly Leu His Gly Leu Thr His Leu Lys Leu Thr Gly Asn 
            420                 425                 430         


His Ala Leu Gln Ser Leu Ile Ser Ser Glu Asn Phe Pro Glu Leu Lys 
        435                 440                 445             


Val Ile Glu Met Pro Tyr Ala Tyr Gln Cys Cys Ala Phe Gly Val Cys 
    450                 455                 460                 


Glu Asn Ala Tyr Lys Ile Ser Asn Gln Trp Asn Lys Gly Asp Asn Ser 
465                 470                 475                 480 


Ser Met Asp Asp Leu His Lys Lys Asp Ala Gly Met Phe Gln Ala Gln 
                485                 490                 495     


Asp Glu Arg Asp Leu Glu Asp Phe Leu Leu Asp Phe Glu Glu Asp Leu 
            500                 505                 510         


Lys Ala Leu His Ser Val Gln Cys Ser Pro Ser Pro Gly Pro Phe Lys 
        515                 520                 525             


Pro Cys Glu His Leu Leu Asp Gly Trp Leu Ile Arg 
    530                 535                 540 


<210>  812
<211>  543
<212>  PRT
<213>  Homo Sapiens

<400>  812

Ala Pro Gln Pro Gly Pro Gly Pro Thr Ala Cys Pro Ala Pro Cys His 
1               5                   10                  15      


Cys Gln Glu Asp Gly Ile Met Leu Ser Ala Asp Cys Ser Glu Leu Gly 
            20                  25                  30          


Leu Ser Ala Val Pro Gly Asp Leu Asp Pro Leu Thr Ala Tyr Leu Asp 
        35                  40                  45              


Leu Ser Met Asn Asn Leu Thr Glu Leu Gln Pro Gly Leu Phe His His 
    50                  55                  60                  


Leu Arg Phe Leu Glu Glu Leu Arg Leu Ser Gly Asn His Leu Ser His 
65                  70                  75                  80  


Ile Pro Gly Gln Ala Phe Ser Gly Leu Tyr Ser Leu Lys Ile Leu Met 
                85                  90                  95      


Leu Gln Asn Asn Gln Leu Gly Gly Ile Pro Ala Glu Ala Leu Trp Glu 
            100                 105                 110         


Leu Pro Ser Leu Gln Ser Leu Arg Leu Asp Ala Asn Leu Ile Ser Leu 
        115                 120                 125             


Val Pro Glu Arg Ser Phe Glu Gly Leu Ser Ser Leu Arg His Leu Trp 
    130                 135                 140                 


Leu Asp Asp Asn Ala Leu Thr Glu Ile Pro Val Arg Ala Leu Asn Asn 
145                 150                 155                 160 


Leu Pro Ala Leu Gln Ala Met Thr Leu Ala Leu Asn Arg Ile Ser His 
                165                 170                 175     


Ile Pro Asp Tyr Ala Phe Gln Asn Leu Thr Ser Leu Val Val Leu His 
            180                 185                 190         


Leu His Asn Asn Arg Ile Gln His Leu Gly Thr His Ser Phe Glu Gly 
        195                 200                 205             


Leu His Asn Leu Glu Thr Leu Asp Leu Asn Tyr Asn Lys Leu Gln Glu 
    210                 215                 220                 


Phe Pro Val Ala Ile Arg Thr Leu Gly Arg Leu Gln Glu Leu Gly Phe 
225                 230                 235                 240 


His Asn Asn Asn Ile Lys Ala Ile Pro Glu Lys Ala Phe Met Gly Asn 
                245                 250                 255     


Pro Leu Leu Gln Thr Ile His Phe Tyr Asp Asn Pro Ile Gln Phe Val 
            260                 265                 270         


Gly Arg Ser Ala Phe Gln Tyr Leu Pro Lys Leu His Thr Leu Ser Leu 
        275                 280                 285             


Asn Gly Ala Met Asp Ile Gln Glu Phe Pro Asp Leu Lys Gly Thr Thr 
    290                 295                 300                 


Ser Leu Glu Ile Leu Thr Leu Thr Arg Ala Gly Ile Arg Leu Leu Pro 
305                 310                 315                 320 


Ser Gly Met Cys Gln Gln Leu Pro Arg Leu Arg Val Leu Glu Leu Ser 
                325                 330                 335     


His Asn Gln Ile Glu Glu Leu Pro Ser Leu His Arg Cys Gln Lys Leu 
            340                 345                 350         


Glu Glu Ile Gly Leu Gln His Asn Arg Ile Trp Glu Ile Gly Ala Asp 
        355                 360                 365             


Thr Phe Ser Gln Leu Ser Ser Leu Gln Ala Leu Asp Leu Ser Trp Asn 
    370                 375                 380                 


Ala Ile Arg Ser Ile His Pro Glu Ala Phe Ser Thr Leu His Ser Leu 
385                 390                 395                 400 


Val Lys Leu Asp Leu Thr Asp Asn Gln Leu Thr Thr Leu Pro Leu Ala 
                405                 410                 415     


Gly Leu Gly Gly Leu Met His Leu Lys Leu Lys Gly Asn Leu Ala Leu 
            420                 425                 430         


Ser Gln Ala Phe Ser Lys Asp Ser Phe Pro Lys Leu Arg Ile Leu Glu 
        435                 440                 445             


Val Pro Tyr Ala Tyr Gln Cys Cys Pro Tyr Gly Met Cys Ala Ser Phe 
    450                 455                 460                 


Phe Lys Ala Ser Gly Gln Trp Glu Ala Glu Asp Leu His Leu Asp Asp 
465                 470                 475                 480 


Glu Glu Ser Ser Lys Arg Pro Leu Gly Leu Leu Ala Arg Gln Ala Glu 
                485                 490                 495     


Asn His Tyr Asp Gln Asp Leu Asp Glu Leu Gln Leu Glu Met Glu Asp 
            500                 505                 510         


Ser Lys Pro His Pro Ser Val Gln Cys Ser Pro Thr Pro Gly Pro Phe 
        515                 520                 525             


Lys Pro Cys Glu Tyr Leu Phe Glu Ser Trp Gly Ile Arg Leu Ala 
    530                 535                 540             


<210>  813
<211>  416
<212>  PRT
<213>  Homo Sapiens

<400>  813

Met Ile Val Phe Leu Val Phe Lys His Leu Phe Ser Leu Arg Leu Ile 
1               5                   10                  15      


Thr Met Phe Phe Leu Leu His Phe Ile Val Leu Ile Asn Val Lys Asp 
            20                  25                  30          


Phe Ala Leu Thr Gln Gly Ser Met Ile Thr Pro Ser Cys Gln Lys Gly 
        35                  40                  45              


Tyr Phe Pro Cys Gly Asn Leu Thr Lys Cys Leu Pro Arg Ala Phe His 
    50                  55                  60                  


Cys Asp Gly Lys Asp Asp Cys Gly Asn Gly Ala Asp Glu Glu Asn Cys 
65                  70                  75                  80  


Gly Asp Thr Ser Gly Trp Ala Thr Ile Phe Gly Thr Val His Gly Asn 
                85                  90                  95      


Ala Asn Ser Val Ala Leu Thr Gln Glu Cys Phe Leu Lys Gln Tyr Pro 
            100                 105                 110         


Gln Cys Cys Asp Cys Lys Glu Thr Glu Leu Glu Cys Val Asn Gly Asp 
        115                 120                 125             


Leu Lys Ser Val Pro Met Ile Ser Asn Asn Val Thr Leu Leu Ser Leu 
    130                 135                 140                 


Lys Lys Asn Lys Ile His Ser Leu Pro Asp Lys Val Phe Ile Lys Tyr 
145                 150                 155                 160 


Thr Lys Leu Lys Lys Ile Phe Leu Gln His Asn Cys Ile Arg His Ile 
                165                 170                 175     


Ser Arg Lys Ala Phe Phe Gly Leu Cys Asn Leu Gln Ile Leu Tyr Leu 
            180                 185                 190         


Asn His Asn Cys Ile Thr Thr Leu Arg Pro Gly Ile Phe Lys Asp Leu 
        195                 200                 205             


His Gln Leu Thr Trp Leu Ile Leu Asp Asp Asn Pro Ile Thr Arg Ile 
    210                 215                 220                 


Ser Gln Arg Leu Phe Thr Gly Leu Asn Ser Leu Phe Phe Leu Ser Met 
225                 230                 235                 240 


Val Asn Asn Tyr Leu Glu Ala Leu Pro Lys Gln Met Cys Ala Gln Met 
                245                 250                 255     


Pro Gln Leu Asn Trp Val Asp Leu Glu Gly Asn Arg Ile Lys Tyr Leu 
            260                 265                 270         


Thr Asn Ser Thr Phe Leu Ser Cys Asp Ser Leu Thr Val Leu Phe Leu 
        275                 280                 285             


Pro Arg Asn Gln Ile Gly Phe Val Pro Glu Lys Thr Phe Ser Ser Leu 
    290                 295                 300                 


Lys Asn Leu Gly Glu Leu Asp Leu Ser Ser Asn Thr Ile Thr Glu Leu 
305                 310                 315                 320 


Ser Pro His Leu Phe Lys Asp Leu Lys Leu Leu Gln Lys Leu Asn Leu 
                325                 330                 335     


Ser Ser Asn Pro Leu Met Tyr Leu His Lys Asn Gln Phe Glu Ser Leu 
            340                 345                 350         


Lys Gln Leu Gln Ser Leu Asp Leu Glu Arg Ile Glu Ile Pro Asn Ile 
        355                 360                 365             


Asn Thr Arg Met Phe Gln Pro Met Lys Asn Leu Ser His Ile Tyr Phe 
    370                 375                 380                 


Lys Asn Phe Arg Tyr Cys Ser Tyr Ala Pro His Val Arg Ile Cys Met 
385                 390                 395                 400 


Pro Leu Thr Asp Gly Ile Ser Ser Phe Glu Asp Leu Leu Ala Asn Asn 
                405                 410                 415     


<210>  814
<211>  337
<212>  PRT
<213>  Homo Sapiens

<400>  814

Glu Ala Leu Cys Pro Glu Pro Cys Asn Cys Val Pro Asp Gly Ala Leu 
1               5                   10                  15      


Arg Cys Pro Gly Pro Thr Ala Gly Leu Thr Arg Leu Ser Leu Ala Tyr 
            20                  25                  30          


Leu Pro Val Lys Val Ile Pro Ser Gln Ala Phe Arg Gly Leu Asn Glu 
        35                  40                  45              


Val Ile Lys Ile Glu Ile Ser Gln Ile Asp Ser Leu Glu Arg Ile Glu 
    50                  55                  60                  


Ala Asn Ala Phe Asp Asn Leu Leu Asn Leu Ser Glu Ile Leu Ile Gln 
65                  70                  75                  80  


Asn Thr Lys Asn Leu Arg Tyr Ile Glu Pro Gly Ala Phe Ile Asn Leu 
                85                  90                  95      


Pro Arg Leu Lys Tyr Leu Ser Ile Cys Asn Thr Gly Ile Arg Lys Phe 
            100                 105                 110         


Pro Asp Val Thr Lys Val Phe Ser Ser Glu Ser Asn Phe Ile Leu Glu 
        115                 120                 125             


Ile Cys Asp Asn Leu His Ile Thr Thr Ile Pro Gly Asn Ala Phe Gln 
    130                 135                 140                 


Gly Met Asn Asn Glu Ser Val Thr Leu Lys Leu Tyr Gly Asn Gly Phe 
145                 150                 155                 160 


Glu Glu Val Gln Ser His Ala Phe Asn Gly Thr Thr Leu Thr Ser Leu 
                165                 170                 175     


Glu Leu Lys Glu Asn Val His Leu Glu Lys Met His Asn Gly Ala Phe 
            180                 185                 190         


Arg Gly Ala Thr Gly Pro Lys Thr Leu Asp Ile Ser Ser Thr Lys Leu 
        195                 200                 205             


Gln Ala Leu Pro Ser Tyr Gly Leu Glu Ser Ile Gln Arg Leu Ile Ala 
    210                 215                 220                 


Thr Ser Ser Tyr Ser Leu Lys Lys Leu Pro Ser Arg Glu Thr Phe Val 
225                 230                 235                 240 


Asn Leu Leu Glu Ala Thr Leu Thr Tyr Pro Ser His Cys Cys Ala Phe 
                245                 250                 255     


Arg Asn Leu Pro Thr Lys Glu Gln Asn Phe Ser His Ser Ile Ser Glu 
            260                 265                 270         


Asn Phe Ser Lys Gln Cys Glu Ser Thr Val Arg Lys Val Asn Asn Lys 
        275                 280                 285             


Thr Leu Tyr Ser Ser Met Leu Ala Glu Ser Glu Leu Ser Gly Trp Asp 
    290                 295                 300                 


Tyr Glu Tyr Gly Phe Cys Leu Pro Lys Thr Pro Arg Cys Ala Pro Glu 
305                 310                 315                 320 


Pro Asp Ala Phe Asn Pro Cys Glu Asp Ile Met Gly Tyr Asp Phe Leu 
                325                 330                 335     


Arg 
    


<210>  815
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  815

Ser Pro Leu Pro Ile Thr Pro Val Asn Ala Thr Cys Ala Ile Arg His 
1               5                   10                  15      


Pro Cys His Asn Asn Leu Met Asn Gln Ile Arg Ser Gln Leu Ala Gln 
            20                  25                  30          


Leu Asn Gly Ser Ala Asn Ala Leu Phe Ile Leu Tyr Tyr Thr Ala Gln 
        35                  40                  45              


Gly Glu Pro Phe Pro Asn Asn Leu Asp Lys Leu Cys Gly Pro Asn Val 
    50                  55                  60                  


Thr Asp Phe Pro Pro Phe His Ala Asn Gly Thr Glu Lys Ala Lys Leu 
65                  70                  75                  80  


Val Glu Leu Tyr Arg Ile Val Val Tyr Leu Gly Thr Ser Leu Gly Asn 
                85                  90                  95      


Ile Thr Arg Asp Gln Lys Ile Leu Asn Pro Ser Ala Leu Ser Leu His 
            100                 105                 110         


Ser Lys Leu Asn Ala Thr Ala Asp Ile Leu Arg Gly Leu Leu Ser Asn 
        115                 120                 125             


Val Leu Cys Arg Leu Cys Ser Lys Tyr His Val Gly His Val Asp Val 
    130                 135                 140                 


Thr Tyr Gly Pro Asp Thr Ser Gly Lys Asp Val Phe Gln Lys Lys Lys 
145                 150                 155                 160 


Leu Gly Cys Gln Leu Leu Gly Lys Tyr Lys Gln Ile Ile Ala Val Leu 
                165                 170                 175     


Ala Gln Ala Phe 
            180 


<210>  816
<211>  789
<212>  PRT
<213>  Homo Sapiens

<400>  816

Gln Lys Lys Gly Ala Pro His Asp Leu Lys Cys Val Thr Asn Asn Leu 
1               5                   10                  15      


Gln Val Trp Asn Cys Ser Trp Lys Ala Pro Ser Gly Thr Gly Arg Gly 
            20                  25                  30          


Thr Asp Tyr Glu Val Cys Ile Glu Asn Arg Ser Arg Ser Cys Tyr Gln 
        35                  40                  45              


Leu Glu Lys Thr Ser Ile Lys Ile Pro Ala Leu Ser His Gly Asp Tyr 
    50                  55                  60                  


Glu Ile Thr Ile Asn Ser Leu His Asp Phe Gly Ser Ser Thr Ser Lys 
65                  70                  75                  80  


Phe Thr Leu Asn Glu Gln Asn Val Ser Leu Ile Pro Asp Thr Pro Glu 
                85                  90                  95      


Ile Leu Asn Leu Ser Ala Asp Phe Ser Thr Ser Thr Leu Tyr Leu Lys 
            100                 105                 110         


Trp Asn Asp Arg Gly Ser Val Phe Pro His Arg Ser Asn Val Ile Trp 
        115                 120                 125             


Glu Ile Lys Val Leu Arg Lys Glu Ser Met Glu Leu Val Lys Leu Val 
    130                 135                 140                 


Thr His Asn Thr Thr Leu Asn Gly Lys Asp Thr Leu His His Trp Ser 
145                 150                 155                 160 


Trp Ala Ser Asp Met Pro Leu Glu Cys Ala Ile His Phe Val Glu Ile 
                165                 170                 175     


Arg Cys Tyr Ile Asp Asn Leu His Phe Ser Gly Leu Glu Glu Trp Ser 
            180                 185                 190         


Asp Trp Ser Pro Val Lys Asn Ile Ser Trp Ile Pro Asp Ser Gln Thr 
        195                 200                 205             


Lys Val Phe Pro Gln Asp Lys Val Ile Leu Val Gly Ser Asp Ile Thr 
    210                 215                 220                 


Phe Cys Cys Val Ser Gln Glu Lys Val Leu Ser Ala Leu Ile Gly His 
225                 230                 235                 240 


Thr Asn Cys Pro Leu Ile His Leu Asp Gly Glu Asn Val Ala Ile Lys 
                245                 250                 255     


Ile Arg Asn Ile Ser Val Ser Ala Ser Ser Gly Thr Asn Val Val Phe 
            260                 265                 270         


Thr Thr Glu Asp Asn Ile Phe Gly Thr Val Ile Phe Ala Gly Tyr Pro 
        275                 280                 285             


Pro Asp Thr Pro Gln Gln Leu Asn Cys Glu Thr His Asp Leu Lys Glu 
    290                 295                 300                 


Ile Ile Cys Ser Trp Asn Pro Gly Arg Val Thr Ala Leu Val Gly Pro 
305                 310                 315                 320 


Arg Ala Thr Ser Tyr Thr Leu Val Glu Ser Phe Ser Gly Lys Tyr Val 
                325                 330                 335     


Arg Leu Lys Arg Ala Glu Ala Pro Thr Asn Glu Ser Tyr Gln Leu Leu 
            340                 345                 350         


Phe Gln Met Leu Pro Asn Gln Glu Ile Tyr Asn Phe Thr Leu Asn Ala 
        355                 360                 365             


His Asn Pro Leu Gly Arg Ser Gln Ser Thr Ile Leu Val Asn Ile Thr 
    370                 375                 380                 


Glu Lys Val Tyr Pro His Thr Pro Thr Ser Phe Lys Val Lys Asp Ile 
385                 390                 395                 400 


Asn Ser Thr Ala Val Lys Leu Ser Trp His Leu Pro Gly Asn Phe Ala 
                405                 410                 415     


Lys Ile Asn Phe Leu Cys Glu Ile Glu Ile Lys Lys Ser Asn Ser Val 
            420                 425                 430         


Gln Glu Gln Arg Asn Val Thr Ile Lys Gly Val Glu Asn Ser Ser Tyr 
        435                 440                 445             


Leu Val Ala Leu Asp Lys Leu Asn Pro Tyr Thr Leu Tyr Thr Phe Arg 
    450                 455                 460                 


Ile Arg Cys Ser Thr Glu Thr Phe Trp Lys Trp Ser Lys Trp Ser Asn 
465                 470                 475                 480 


Lys Lys Gln His Leu Thr Thr Glu Ala Ser Pro Ser Lys Gly Pro Asp 
                485                 490                 495     


Thr Trp Arg Glu Trp Ser Ser Asp Gly Lys Asn Leu Ile Ile Tyr Trp 
            500                 505                 510         


Lys Pro Leu Pro Ile Asn Glu Ala Asn Gly Lys Ile Leu Ser Tyr Asn 
        515                 520                 525             


Val Ser Cys Ser Ser Asp Glu Glu Thr Gln Ser Leu Ser Glu Ile Pro 
    530                 535                 540                 


Asp Pro Gln His Lys Ala Glu Ile Arg Leu Asp Lys Asn Asp Tyr Ile 
545                 550                 555                 560 


Ile Ser Val Val Ala Lys Asn Ser Val Gly Ser Ser Pro Pro Ser Lys 
                565                 570                 575     


Ile Ala Ser Met Glu Ile Pro Asn Asp Asp Leu Lys Ile Glu Gln Val 
            580                 585                 590         


Val Gly Met Gly Lys Gly Ile Leu Leu Thr Trp His Tyr Asp Pro Asn 
        595                 600                 605             


Met Thr Cys Asp Tyr Val Ile Lys Trp Cys Asn Ser Ser Arg Ser Glu 
    610                 615                 620                 


Pro Cys Leu Met Asp Trp Arg Lys Val Pro Ser Asn Ser Thr Glu Thr 
625                 630                 635                 640 


Val Ile Glu Ser Asp Glu Phe Arg Pro Gly Ile Arg Tyr Asn Phe Phe 
                645                 650                 655     


Leu Tyr Gly Cys Arg Asn Gln Gly Tyr Gln Leu Leu Arg Ser Met Ile 
            660                 665                 670         


Gly Tyr Ile Glu Glu Leu Ala Pro Ile Val Ala Pro Asn Phe Thr Val 
        675                 680                 685             


Glu Asp Thr Ser Ala Asp Ser Ile Leu Val Lys Trp Glu Asp Ile Pro 
    690                 695                 700                 


Val Glu Glu Leu Arg Gly Phe Leu Arg Gly Tyr Leu Phe Tyr Phe Gly 
705                 710                 715                 720 


Lys Gly Glu Arg Asp Thr Ser Lys Met Arg Val Leu Glu Ser Gly Arg 
                725                 730                 735     


Ser Asp Ile Lys Val Lys Asn Ile Thr Asp Ile Ser Gln Lys Thr Leu 
            740                 745                 750         


Arg Ile Ala Asp Leu Gln Gly Lys Thr Ser Tyr His Leu Val Leu Arg 
        755                 760                 765             


Ala Tyr Thr Asp Gly Gly Val Gly Pro Glu Lys Ser Met Tyr Val Val 
    770                 775                 780                 


Thr Lys Glu Asn Ser 
785                 


<210>  817
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  817

Pro Arg Thr His Val Gln Ala Gly Thr Leu Pro Lys Pro Thr Leu Trp 
1               5                   10                  15      


Ala Glu Pro Gly Ser Val Ile Thr Gln Gly Ser Pro Val Thr Leu Trp 
            20                  25                  30          


Cys Gln Gly Ile Leu Glu Thr Gln Glu Tyr Arg Leu Tyr Arg Glu Lys 
        35                  40                  45              


Lys Thr Ala Pro Trp Ile Thr Arg Ile Pro Gln Glu Ile Val Lys Lys 
    50                  55                  60                  


Gly Gln Phe Pro Ile Pro Ser Ile Thr Trp Glu His Thr Gly Arg Tyr 
65                  70                  75                  80  


Arg Cys Phe Tyr Gly Ser His Thr Ala Gly Trp Ser Glu Pro Ser Asp 
                85                  90                  95      


Pro Leu Glu Leu Val Val Thr Gly Ala Tyr Ile Lys Pro Thr Leu Ser 
            100                 105                 110         


Ala Leu Pro Ser Pro Val Val Thr Ser Gly Gly Asn Val Thr Leu His 
        115                 120                 125             


Cys Val Ser Gln Val Ala Phe Gly Ser Phe Ile Leu Cys Lys Glu Gly 
    130                 135                 140                 


Glu Asp Glu His Pro Gln Cys Leu Asn Ser Gln Pro Arg Thr His Gly 
145                 150                 155                 160 


Trp Ser Arg Ala Ile Phe Ser Val Gly Pro Val Ser Pro Ser Arg Arg 
                165                 170                 175     


Trp Ser Tyr Arg Cys Tyr Ala Tyr Asp Ser Asn Ser Pro His Val Trp 
            180                 185                 190         


Ser Leu Pro Ser Asp Leu Leu Glu Leu Leu Val Leu Gly Val Ser Lys 
        195                 200                 205             


Lys Pro Ser Leu Ser Val Gln Pro Gly Pro Ile Val Ala Pro Gly Glu 
    210                 215                 220                 


Ser Leu Thr Leu Gln Cys Val Ser Asp Val Ser Tyr Asp Arg Phe Val 
225                 230                 235                 240 


Leu Tyr Lys Glu Gly Glu Arg Asp Phe Leu Gln Leu Pro Gly Pro Gln 
                245                 250                 255     


Pro Gln Ala Gly Leu Ser Gln Ala Asn Phe Thr Leu Gly Pro Val Ser 
            260                 265                 270         


Arg Ser Tyr Gly Gly Gln Tyr Arg Cys Ser Gly Ala Tyr Asn Leu Ser 
        275                 280                 285             


Ser Glu Trp Ser Ala Pro Ser Asp Pro Leu Asp Ile Leu Ile Ala Gly 
    290                 295                 300                 


Gln Phe Arg Gly Arg Pro Phe Ile Ser Val His Pro Gly Pro Thr Val 
305                 310                 315                 320 


Ala Ser Gly Glu Asn Val Thr Leu Leu Cys Gln Ser Trp Gly Pro Phe 
                325                 330                 335     


His Thr Phe Leu Leu Thr Lys Ala Gly Ala Ala Asp Ala Pro Leu Arg 
            340                 345                 350         


Leu Arg Ser Ile His Glu Tyr Pro Lys Tyr Gln Ala Glu Phe Pro Met 
        355                 360                 365             


Ser Pro Val Thr Ser Ala His Ser Gly Thr Tyr Arg Cys Tyr Gly Ser 
    370                 375                 380                 


Leu Ser Ser Asn Pro Tyr Leu Leu Ser His Pro Ser Asp Ser Leu Glu 
385                 390                 395                 400 


Leu Met Val Ser Gly Ala Ala Glu Thr Leu Ser Pro Pro Gln Asn Lys 
                405                 410                 415     


Ser Asp Ser Lys Ala Gly Ala Ala Asn Thr Leu Ser Pro Ser Gln Asn 
            420                 425                 430         


Lys Thr Ala Ser His Pro Gln Asp Tyr Thr Val Glu Asn 
        435                 440                 445 


<210>  818
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  818

Gly His Leu Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Ile Gln Gly Ser Pro Val Thr Leu Arg Cys Gln Gly Ser Leu Gln Ala 
            20                  25                  30          


Glu Glu Tyr His Leu Tyr Arg Glu Asn Lys Ser Ala Ser Trp Val Arg 
        35                  40                  45              


Arg Ile Gln Glu Pro Gly Lys Asn Gly Gln Phe Pro Ile Pro Ser Ile 
    50                  55                  60                  


Thr Trp Glu His Ala Gly Arg Tyr His Cys Gln Tyr Tyr Ser His Asn 
65                  70                  75                  80  


His Ser Ser Glu Tyr Ser Asp Pro Leu Glu Leu Val Val Thr Gly Ala 
                85                  90                  95      


Tyr Ser Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val Thr Leu 
            100                 105                 110         


Gly Gly Asn Val Thr Leu Gln Cys Val Ser Gln Val Ala Phe Asp Gly 
        115                 120                 125             


Phe Ile Leu Cys Lys Glu Gly Glu Asp Glu His Pro Gln Arg Leu Asn 
    130                 135                 140                 


Ser His Ser His Ala Arg Gly Trp Ser Trp Ala Ile Phe Ser Val Gly 
145                 150                 155                 160 


Pro Val Ser Pro Ser Arg Arg Trp Ser Tyr Arg Cys Tyr Ala Tyr Asp 
                165                 170                 175     


Ser Asn Ser Pro Tyr Val Trp Ser Leu Pro Ser Asp Leu Leu Glu Leu 
            180                 185                 190         


Leu Val Pro Gly Val Ser Lys Lys Pro Ser Leu Ser Val Gln Pro Gly 
        195                 200                 205             


Pro Met Val Ala Pro Gly Glu Ser Leu Thr Leu Gln Cys Val Ser Asp 
    210                 215                 220                 


Val Gly Tyr Asp Arg Phe Val Leu Tyr Lys Glu Gly Glu Arg Asp Phe 
225                 230                 235                 240 


Leu Gln Arg Pro Gly Trp Gln Pro Gln Ala Gly Leu Ser Gln Ala Asn 
                245                 250                 255     


Phe Thr Leu Gly Pro Val Ser Pro Ser His Gly Gly Gln Tyr Arg Cys 
            260                 265                 270         


Tyr Ser Ala His Asn Leu Ser Ser Glu Trp Ser Ala Pro Ser Asp Pro 
        275                 280                 285             


Leu Asp Ile Leu Ile Thr Gly Gln Phe Tyr Asp Arg Pro Ser Leu Ser 
    290                 295                 300                 


Val Gln Pro Val Pro Thr Val Ala Pro Gly Lys Asn Val Thr Leu Leu 
305                 310                 315                 320 


Cys Gln Ser Arg Gly Gln Phe His Thr Phe Leu Leu Thr Lys Glu Gly 
                325                 330                 335     


Ala Gly His Pro Pro Leu His Leu Arg Ser Glu His Gln Ala Gln Gln 
            340                 345                 350         


Asn Gln Ala Glu Phe Arg Met Gly Pro Val Thr Ser Ala His Val Gly 
        355                 360                 365             


Thr Tyr Arg Cys Tyr Ser Ser Leu Ser Ser Asn Pro Tyr Leu Leu Ser 
    370                 375                 380                 


Leu Pro Ser Asp Pro Leu Glu Leu Val Val Ser Ala Ser Leu Gly Gln 
385                 390                 395                 400 


His Pro Gln Asp Tyr Thr Val Glu Asn 
                405                 


<210>  819
<211>  416
<212>  PRT
<213>  Homo Sapiens

<400>  819

Gly Pro Leu Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Thr Gln Gly Ser Pro Val Thr Leu Arg Cys Gln Gly Ser Leu Glu Thr 
            20                  25                  30          


Gln Glu Tyr His Leu Tyr Arg Glu Lys Lys Thr Ala Leu Trp Ile Thr 
        35                  40                  45              


Arg Ile Pro Gln Glu Leu Val Lys Lys Gly Gln Phe Pro Ile Leu Ser 
    50                  55                  60                  


Ile Thr Trp Glu His Ala Gly Arg Tyr Cys Cys Ile Tyr Gly Ser His 
65                  70                  75                  80  


Thr Val Gly Leu Ser Glu Ser Ser Asp Pro Leu Glu Leu Val Val Thr 
                85                  90                  95      


Gly Ala Tyr Ser Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val 
            100                 105                 110         


Thr Ser Gly Gly Asn Val Thr Ile Gln Cys Asp Ser Gln Val Ala Phe 
        115                 120                 125             


Asp Gly Phe Ile Leu Cys Lys Glu Gly Glu Asp Glu His Pro Gln Cys 
    130                 135                 140                 


Leu Asn Ser His Ser His Ala Arg Gly Ser Ser Arg Ala Ile Phe Ser 
145                 150                 155                 160 


Val Gly Pro Val Ser Pro Ser Arg Arg Trp Ser Tyr Arg Cys Tyr Gly 
                165                 170                 175     


Tyr Asp Ser Arg Ala Pro Tyr Val Trp Ser Leu Pro Ser Asp Leu Leu 
            180                 185                 190         


Gly Leu Leu Val Pro Gly Val Ser Lys Lys Pro Ser Leu Ser Val Gln 
        195                 200                 205             


Pro Gly Pro Val Val Ala Pro Gly Glu Lys Leu Thr Phe Gln Cys Gly 
    210                 215                 220                 


Ser Asp Ala Gly Tyr Asp Arg Phe Val Leu Tyr Lys Glu Trp Gly Arg 
225                 230                 235                 240 


Asp Phe Leu Gln Arg Pro Gly Arg Gln Pro Gln Ala Gly Leu Ser Gln 
                245                 250                 255     


Ala Asn Phe Thr Leu Gly Pro Val Ser Arg Ser Tyr Gly Gly Gln Tyr 
            260                 265                 270         


Thr Cys Ser Gly Ala Tyr Asn Leu Ser Ser Glu Trp Ser Ala Pro Ser 
        275                 280                 285             


Asp Pro Leu Asp Ile Leu Ile Thr Gly Gln Ile Arg Ala Arg Pro Phe 
    290                 295                 300                 


Leu Ser Val Arg Pro Gly Pro Thr Val Ala Ser Gly Glu Asn Val Thr 
305                 310                 315                 320 


Leu Leu Cys Gln Ser Gln Gly Gly Met His Thr Phe Leu Leu Thr Lys 
                325                 330                 335     


Glu Gly Ala Ala Asp Ser Pro Leu Arg Leu Lys Ser Lys Arg Gln Ser 
            340                 345                 350         


His Lys Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala His 
        355                 360                 365             


Ala Gly Thr Tyr Arg Cys Tyr Gly Ser Leu Ser Ser Asn Pro Tyr Leu 
    370                 375                 380                 


Leu Thr His Pro Ser Asp Pro Leu Glu Leu Val Val Ser Gly Ala Ala 
385                 390                 395                 400 


Glu Thr Leu Ser Pro Pro Gln Asn Lys Ser Asp Ser Lys Ala Gly Glu 
                405                 410                 415     


<210>  820
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  820

Glu Asn Leu Pro Lys Pro Ile Leu Trp Ala Glu Pro Gly Pro Val Ile 
1               5                   10                  15      


Thr Trp His Asn Pro Val Thr Ile Trp Cys Gln Gly Thr Leu Glu Ala 
            20                  25                  30          


Gln Gly Tyr Arg Leu Asp Lys Glu Gly Asn Ser Met Ser Arg His Ile 
        35                  40                  45              


Leu Lys Thr Leu Glu Ser Glu Asn Lys Val Lys Leu Ser Ile Pro Ser 
    50                  55                  60                  


Met Met Trp Glu His Ala Gly Arg Tyr His Cys Tyr Tyr Gln Ser Pro 
65                  70                  75                  80  


Ala Gly Trp Ser Glu Pro Ser Asp Pro Leu Glu Leu Val Val Thr Ala 
                85                  90                  95      


Tyr Ser Arg Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val Thr Ser 
            100                 105                 110         


Gly Val Asn Val Thr Leu Arg Cys Ala Ser Arg Leu Gly Leu Gly Arg 
        115                 120                 125             


Phe Thr Leu Ile Glu Glu Gly Asp His Arg Leu Ser Trp Thr Leu Asn 
    130                 135                 140                 


Ser His Gln His Asn His Gly Lys Phe Gln Ala Leu Phe Pro Met Gly 
145                 150                 155                 160 


Pro Leu Thr Phe Ser Asn Arg Gly Thr Phe Arg Cys Tyr Gly Tyr Glu 
                165                 170                 175     


Asn Asn Thr Pro Tyr Val Trp Ser Glu Pro Ser Asp Pro Leu Gln Leu 
            180                 185                 190         


Leu Val Ser Gly Val Ser Arg Lys Pro Ser Leu Leu Thr Leu Gln Gly 
        195                 200                 205             


Pro Val Val Thr Pro Gly Glu Asn Leu Thr Leu Gln Cys Gly Ser Asp 
    210                 215                 220                 


Val Gly Tyr Ile Arg Tyr Thr Leu Tyr Lys Glu Gly Ala Asp Gly Leu 
225                 230                 235                 240 


Pro Gln Arg Pro Gly Arg Gln Pro Gln Ala Gly Leu Ser Gln Ala Asn 
                245                 250                 255     


Phe Thr Leu Ser Pro Val Ser Arg Ser Tyr Gly Gly Gln Tyr Arg Cys 
            260                 265                 270         


Tyr Gly Ala His Asn Val Ser Ser Glu Trp Ser Ala Pro Ser Asp Pro 
        275                 280                 285             


Leu Asp Ile Leu Ile Ala Gly Gln Ile Ser Asp Arg Pro Ser Leu Ser 
    290                 295                 300                 


Val Gln Pro Gly Pro Thr Val Thr Ser Gly Glu Lys Val Thr Leu Leu 
305                 310                 315                 320 


Cys Gln Ser Trp Asp Pro Met Phe Thr Phe Leu Leu Thr Lys Glu Gly 
                325                 330                 335     


Ala Ala His Pro Pro Leu Arg Leu Arg Ser Met Tyr Gly Ala His Lys 
            340                 345                 350         


Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala His Ala Gly 
        355                 360                 365             


Thr Tyr Arg Cys Tyr Gly Ser Arg Ser Ser Asn Pro Tyr Leu Leu Ser 
    370                 375                 380                 


His Pro Ser Glu Pro Leu Glu Leu Val Val Ser Gly Ala Thr Glu Thr 
385                 390                 395                 400 


Leu Asn Pro Ala Gln Lys Lys Ser Asp Ser Lys Thr Ala Pro His Leu 
                405                 410                 415     


Gln Asp Tyr Thr Val Glu Asn 
            420             


<210>  821
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  821

Gly Asn Leu Ser Lys Ala Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Ser Arg Gly Asn Ser Val Thr Ile Arg Cys Gln Gly Thr Leu Glu Ala 
            20                  25                  30          


Gln Glu Tyr Arg Leu Val Lys Glu Gly Ser Pro Glu Pro Trp Asp Thr 
        35                  40                  45              


Gln Asn Pro Leu Glu Pro Lys Asn Lys Ala Arg Phe Ser Ile Pro Ser 
    50                  55                  60                  


Met Thr Glu His His Ala Gly Arg Tyr Arg Cys Tyr Tyr Tyr Ser Pro 
65                  70                  75                  80  


Ala Gly Trp Ser Glu Pro Ser Asp Pro Leu Glu Leu Val Val Thr Gly 
                85                  90                  95      


Phe Tyr Asn Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val Thr 
            100                 105                 110         


Ser Gly Glu Asn Val Thr Leu Gln Cys Gly Ser Arg Leu Arg Phe Asp 
        115                 120                 125             


Arg Phe Ile Leu Thr Glu Glu Gly Asp His Lys Leu Ser Trp Thr Leu 
    130                 135                 140                 


Asp Ser Gln Leu Thr Pro Ser Gly Gln Phe Gln Ala Leu Phe Pro Val 
145                 150                 155                 160 


Gly Pro Val Thr Pro Ser His Arg Trp Met Leu Arg Cys Tyr Gly Ser 
                165                 170                 175     


Arg Arg His Ile Leu Gln Val Trp Ser Glu Pro Ser Asp Leu Leu Glu 
            180                 185                 190         


Ile Pro Val Ser Gly Ala Ala Asp Asn Leu Ser Pro Ser Gln Asn Lys 
        195                 200                 205             


Ser Asp Ser Gly Thr Ala Ser His Leu Gln Asp Tyr Ala Val Glu Asn 
    210                 215                 220                 


Leu Ile Arg 
225         


<210>  822
<211>  438
<212>  PRT
<213>  Homo Sapiens

<400>  822

Gly His Leu Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Thr Gln Gly Ser Pro Val Thr Leu Arg Cys Gln Gly Gly Gln Glu Thr 
            20                  25                  30          


Gln Glu Tyr Arg Leu Tyr Arg Glu Lys Lys Thr Ala Pro Trp Ile Thr 
        35                  40                  45              


Arg Ile Pro Gln Glu Leu Val Lys Lys Gly Gln Phe Pro Ile Pro Ser 
    50                  55                  60                  


Ile Thr Trp Glu His Ala Gly Arg Tyr Arg Cys Tyr Tyr Gly Ser Asp 
65                  70                  75                  80  


Thr Ala Gly Arg Ser Glu Ser Ser Asp Pro Leu Glu Leu Val Val Thr 
                85                  90                  95      


Gly Ala Tyr Ile Lys Pro Thr Leu Ser Ala Gln Pro Ser Pro Val Val 
            100                 105                 110         


Asn Ser Gly Gly Asn Val Thr Leu Gln Cys Asp Ser Gln Val Ala Phe 
        115                 120                 125             


Asp Gly Phe Ile Leu Cys Lys Glu Gly Glu Asp Glu His Pro Gln Cys 
    130                 135                 140                 


Leu Asn Ser Gln Pro His Ala Arg Gly Ser Ser Arg Ala Ile Phe Ser 
145                 150                 155                 160 


Val Gly Pro Val Ser Pro Ser Arg Arg Trp Trp Tyr Arg Cys Tyr Ala 
                165                 170                 175     


Tyr Asp Ser Asn Ser Pro Tyr Glu Trp Ser Leu Pro Ser Asp Leu Leu 
            180                 185                 190         


Glu Leu Leu Val Leu Gly Val Ser Lys Lys Pro Ser Leu Ser Val Gln 
        195                 200                 205             


Pro Gly Pro Ile Val Ala Pro Glu Glu Thr Leu Thr Leu Gln Cys Gly 
    210                 215                 220                 


Ser Asp Ala Gly Tyr Asn Arg Phe Val Leu Tyr Lys Asp Gly Glu Arg 
225                 230                 235                 240 


Asp Phe Leu Gln Leu Ala Gly Ala Gln Pro Gln Ala Gly Leu Ser Gln 
                245                 250                 255     


Ala Asn Phe Thr Leu Gly Pro Val Ser Arg Ser Tyr Gly Gly Gln Tyr 
            260                 265                 270         


Arg Cys Tyr Gly Ala His Asn Leu Ser Ser Glu Trp Ser Ala Pro Ser 
        275                 280                 285             


Asp Pro Leu Asp Ile Leu Ile Ala Gly Gln Phe Tyr Asp Arg Val Ser 
    290                 295                 300                 


Leu Ser Val Gln Pro Gly Pro Thr Val Ala Ser Gly Glu Asn Val Thr 
305                 310                 315                 320 


Leu Leu Cys Gln Ser Gln Gly Trp Met Gln Thr Phe Leu Leu Thr Lys 
                325                 330                 335     


Glu Gly Ala Ala Asp Asp Pro Trp Arg Leu Arg Ser Thr Tyr Gln Ser 
            340                 345                 350         


Gln Lys Tyr Gln Ala Glu Phe Pro Met Gly Pro Val Thr Ser Ala His 
        355                 360                 365             


Ala Gly Thr Tyr Arg Cys Tyr Gly Ser Gln Ser Ser Lys Pro Tyr Leu 
    370                 375                 380                 


Leu Thr His Pro Ser Asp Pro Leu Glu Leu Val Val Ser Gly Pro Ser 
385                 390                 395                 400 


Gly Gly Pro Ser Ser Pro Thr Thr Gly Pro Thr Ser Thr Ser Gly Pro 
                405                 410                 415     


Glu Asp Gln Pro Leu Thr Pro Thr Gly Ser Asp Pro Gln Ser Gly Leu 
            420                 425                 430         


Gly Arg His Leu Gly Val 
        435             


<210>  823
<211>  440
<212>  PRT
<213>  Homo Sapiens

<400>  823

Gln Thr Gly Thr Ile Pro Lys Pro Thr Leu Trp Ala Glu Pro Asp Ser 
1               5                   10                  15      


Val Ile Thr Gln Gly Ser Pro Val Thr Leu Ser Cys Gln Gly Ser Leu 
            20                  25                  30          


Glu Ala Gln Glu Tyr Arg Leu Tyr Arg Glu Lys Lys Ser Ala Ser Trp 
        35                  40                  45              


Ile Thr Arg Ile Arg Pro Glu Leu Val Lys Asn Gly Gln Phe His Ile 
    50                  55                  60                  


Pro Ser Ile Thr Trp Glu His Thr Gly Arg Tyr Gly Cys Gln Tyr Tyr 
65                  70                  75                  80  


Ser Arg Ala Arg Trp Ser Glu Leu Ser Asp Pro Leu Val Leu Val Met 
                85                  90                  95      


Thr Gly Ala Tyr Pro Lys Pro Thr Leu Ser Ala Gln Pro Ser Pro Val 
            100                 105                 110         


Val Thr Ser Gly Gly Arg Val Thr Leu Gln Cys Glu Ser Gln Val Ala 
        115                 120                 125             


Phe Gly Gly Phe Ile Leu Cys Lys Glu Gly Glu Asp Glu His Pro Gln 
    130                 135                 140                 


Cys Leu Asn Ser Gln Pro His Ala Arg Gly Ser Ser Arg Ala Ile Phe 
145                 150                 155                 160 


Ser Val Gly Pro Val Ser Pro Asn Arg Arg Trp Ser His Arg Cys Tyr 
                165                 170                 175     


Gly Tyr Asp Leu Asn Ser Pro Tyr Val Trp Ser Ser Pro Ser Asp Leu 
            180                 185                 190         


Leu Glu Leu Leu Val Pro Gly Val Ser Lys Lys Pro Ser Leu Ser Val 
        195                 200                 205             


Gln Pro Gly Pro Val Val Ala Pro Gly Glu Ser Leu Thr Leu Gln Cys 
    210                 215                 220                 


Val Ser Asp Val Gly Tyr Asp Arg Phe Val Leu Tyr Lys Glu Gly Glu 
225                 230                 235                 240 


Arg Asp Leu Arg Gln Leu Pro Gly Arg Gln Pro Gln Ala Gly Leu Ser 
                245                 250                 255     


Gln Ala Asn Phe Thr Leu Gly Pro Val Ser Arg Ser Tyr Gly Gly Gln 
            260                 265                 270         


Tyr Arg Cys Tyr Gly Ala Tyr Asn Leu Ser Ser Glu Trp Ser Ala Pro 
        275                 280                 285             


Ser Asp Pro Leu Asp Ile Leu Ile Thr Gly Gln Ile His Gly Thr Pro 
    290                 295                 300                 


Phe Ile Ser Val Gln Pro Gly Pro Thr Val Ala Ser Gly Glu Asn Val 
305                 310                 315                 320 


Thr Leu Leu Cys Gln Ser Trp Arg Gln Phe His Thr Phe Leu Leu Thr 
                325                 330                 335     


Lys Ala Gly Ala Ala Asp Ala Pro Leu Arg Leu Arg Ser Ile His Glu 
            340                 345                 350         


Tyr Pro Lys Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala 
        355                 360                 365             


His Ala Gly Thr Tyr Arg Cys Tyr Gly Ser Leu Asn Ser Asp Pro Tyr 
    370                 375                 380                 


Leu Leu Ser His Pro Ser Glu Pro Leu Glu Leu Val Val Ser Gly Pro 
385                 390                 395                 400 


Ser Met Gly Ser Ser Pro Pro Pro Thr Gly Pro Ile Ser Thr Pro Ala 
                405                 410                 415     


Gly Pro Glu Asp Gln Pro Leu Thr Pro Thr Gly Ser Asp Pro Gln Ser 
            420                 425                 430         


Gly Leu Gly Arg His Leu Gly Val 
        435                 440 


<210>  824
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  824

Gly Pro Phe Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Ser Trp Gly Ser Pro Val Thr Ile Trp Cys Gln Gly Ser Gln Glu Ala 
            20                  25                  30          


Gln Glu Tyr Arg Leu His Lys Glu Gly Ser Pro Glu Pro Leu Asp Arg 
        35                  40                  45              


Asn Asn Pro Leu Glu Pro Lys Asn Lys Ala Arg Phe Ser Ile Pro Ser 
    50                  55                  60                  


Met Thr Glu His His Ala Gly Arg Tyr Arg Cys His Tyr Tyr Ser Ser 
65                  70                  75                  80  


Ala Gly Trp Ser Glu Pro Ser Asp Pro Leu Glu Met Val Met Thr Gly 
                85                  90                  95      


Ala Tyr Ser Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val Ala 
            100                 105                 110         


Ser Gly Gly Asn Met Thr Leu Arg Cys Gly Ser Gln Lys Gly Tyr His 
        115                 120                 125             


His Phe Val Leu Met Lys Glu Gly Glu His Gln Leu Pro Arg Thr Leu 
    130                 135                 140                 


Asp Ser Gln Gln Leu His Ser Arg Gly Phe Gln Ala Leu Phe Pro Val 
145                 150                 155                 160 


Gly Pro Val Thr Pro Ser His Arg Trp Arg Phe Thr Cys Tyr Tyr Tyr 
                165                 170                 175     


Tyr Thr Asn Thr Pro Trp Val Trp Ser His Pro Ser Asp Pro Leu Glu 
            180                 185                 190         


Ile Leu Pro Ser Gly Val Ser Arg Lys Pro Ser Leu Leu Thr Leu Gln 
        195                 200                 205             


Gly Pro Val Leu Ala Pro Gly Gln Ser Leu Thr Leu Gln Cys Gly Ser 
    210                 215                 220                 


Asp Val Gly Tyr Asn Arg Phe Val Leu Tyr Lys Glu Gly Glu Arg Asp 
225                 230                 235                 240 


Phe Leu Gln Arg Pro Gly Gln Gln Pro Gln Ala Gly Leu Ser Gln Ala 
                245                 250                 255     


Asn Phe Thr Leu Gly Pro Val Ser Pro Ser Asn Gly Gly Gln Tyr Arg 
            260                 265                 270         


Cys Tyr Gly Ala His Asn Leu Ser Ser Glu Trp Ser Ala Pro Ser Asp 
        275                 280                 285             


Pro Leu Asn Ile Leu Met Ala Gly Gln Ile Tyr Asp Thr Val Ser Leu 
    290                 295                 300                 


Ser Ala Gln Pro Gly Pro Thr Val Ala Ser Gly Glu Asn Val Thr Leu 
305                 310                 315                 320 


Leu Cys Gln Ser Trp Trp Gln Phe Asp Thr Phe Leu Leu Thr Lys Glu 
                325                 330                 335     


Gly Ala Ala His Pro Pro Leu Arg Leu Arg Ser Met Tyr Gly Ala His 
            340                 345                 350         


Lys Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala His Ala 
        355                 360                 365             


Gly Thr Tyr Arg Cys Tyr Gly Ser Tyr Ser Ser Asn Pro His Leu Leu 
    370                 375                 380                 


Ser His Pro Ser Glu Pro Leu Glu Leu Val Val Ser Gly His Ser Gly 
385                 390                 395                 400 


Gly Ser Ser Leu Pro Pro Thr Gly Pro Pro Ser Thr Pro Gly Leu Gly 
                405                 410                 415     


Arg Tyr Leu Glu 
            420 


<210>  825
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  825

Gln Ala Gly Pro Leu Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser 
1               5                   10                  15      


Val Ile Ser Trp Gly Asn Ser Val Thr Ile Trp Cys Gln Gly Thr Leu 
            20                  25                  30          


Glu Ala Arg Glu Tyr Arg Leu Asp Lys Glu Glu Ser Pro Ala Pro Trp 
        35                  40                  45              


Asp Arg Gln Asn Pro Leu Glu Pro Lys Asn Lys Ala Arg Phe Ser Ile 
    50                  55                  60                  


Pro Ser Met Thr Glu Asp Tyr Ala Gly Arg Tyr Arg Cys Tyr Tyr Arg 
65                  70                  75                  80  


Ser Pro Val Gly Trp Ser Gln Pro Ser Asp Pro Leu Glu Leu Val Met 
                85                  90                  95      


Thr Gly Ala Tyr Ser Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Leu 
            100                 105                 110         


Val Thr Ser Gly Lys Ser Val Thr Leu Leu Cys Gln Ser Arg Ser Pro 
        115                 120                 125             


Met Asp Thr Phe Leu Leu Ile Lys Glu Arg Ala Ala His Pro Leu Leu 
    130                 135                 140                 


His Leu Arg Ser Glu His Gly Ala Gln Gln His Gln Ala Glu Phe Pro 
145                 150                 155                 160 


Met Ser Pro Val Thr Ser Val His Gly Gly Thr Tyr Arg Cys Phe Ser 
                165                 170                 175     


Ser His Gly Phe Ser His Tyr Leu Leu Ser His Pro Ser Asp Pro Leu 
            180                 185                 190         


Glu Leu Ile Val Ser Gly Ser Leu Glu Gly Pro Arg Pro Ser Pro Thr 
        195                 200                 205             


Arg Ser Val Ser Thr Ala Ala Gly Pro Glu Asp Gln Pro Leu Met Pro 
    210                 215                 220                 


Thr Gly Ser Val Pro His Ser Gly Leu Arg Arg His Trp Glu 
225                 230                 235             


<210>  826
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  826

Gly Thr Leu Pro Lys Pro Thr Leu Trp Ala Glu Pro Ala Ser Val Ile 
1               5                   10                  15      


Ala Arg Gly Lys Pro Val Thr Leu Trp Cys Gln Gly Pro Leu Glu Thr 
            20                  25                  30          


Glu Glu Tyr Arg Leu Asp Lys Glu Gly Leu Pro Trp Ala Arg Lys Arg 
        35                  40                  45              


Gln Asn Pro Leu Glu Pro Gly Ala Lys Ala Lys Phe His Ile Pro Ser 
    50                  55                  60                  


Thr Val Tyr Asp Ser Ala Gly Arg Tyr Arg Cys Tyr Tyr Glu Thr Pro 
65                  70                  75                  80  


Ala Gly Trp Ser Glu Pro Ser Asp Pro Leu Glu Leu Val Ala Thr Gly 
                85                  90                  95      


Phe Tyr Ala Glu Pro Thr Leu Leu Ala Leu Pro Ser Pro Val Val Ala 
            100                 105                 110         


Ser Gly Gly Asn Val Thr Leu Gln Cys Asp Thr Leu Asp Gly Leu Leu 
        115                 120                 125             


Thr Phe Val Leu Val Glu Glu Glu Gln Lys Leu Pro Arg Thr Leu Tyr 
    130                 135                 140                 


Ser Gln Lys Leu Pro Lys Gly Pro Ser Gln Ala Leu Phe Pro Val Gly 
145                 150                 155                 160 


Pro Val Thr Pro Ser Cys Arg Trp Arg Phe Arg Cys Tyr Tyr Tyr Tyr 
                165                 170                 175     


Arg Lys Asn Pro Gln Val Trp Ser Asn Pro Ser Asp Leu Leu Glu Ile 
            180                 185                 190         


Leu Val Pro Gly Val Ser Arg Lys Pro Ser Leu Leu Ile Pro Gln Gly 
        195                 200                 205             


Ser Val Val Ala Arg Gly Gly Ser Leu Thr Leu Gln Cys Arg Ser Asp 
    210                 215                 220                 


Val Gly Tyr Asp Ile Phe Val Leu Tyr Lys Glu Gly Glu His Asp Leu 
225                 230                 235                 240 


Val Gln Gly Ser Gly Gln Gln Pro Gln Ala Gly Leu Ser Gln Ala Asn 
                245                 250                 255     


Phe Thr Leu Gly Pro Val Ser Arg Ser His Gly Gly Gln Tyr Arg Cys 
            260                 265                 270         


Tyr Gly Ala His Asn Leu Ser Pro Arg Trp Ser Ala Pro Ser Asp Pro 
        275                 280                 285             


Leu Asp Ile Leu Ile Ala Gly Leu Ile Pro Asp Ile Pro Ala Leu Ser 
    290                 295                 300                 


Val Gln Pro Gly Pro Lys Val Ala Ser Gly Glu Asn Val Thr Leu Leu 
305                 310                 315                 320 


Cys Gln Ser Trp His Gln Ile Asp Thr Phe Phe Leu Thr Lys Glu Gly 
                325                 330                 335     


Ala Ala His Pro Pro Leu Cys Leu Lys Ser Lys Tyr Gln Ser Tyr Arg 
            340                 345                 350         


His Gln Ala Glu Phe Ser Met Ser Pro Val Thr Ser Ala Gln Gly Gly 
        355                 360                 365             


Thr Tyr Arg Cys Tyr Ser Ala Ile Arg Ser Tyr Pro Tyr Leu Leu Ser 
    370                 375                 380                 


Ser Pro Ser Tyr Pro Gln Glu Leu Val Val Ser Gly Pro Ser Gly Asp 
385                 390                 395                 400 


Pro Ser Leu Ser Pro Thr Gly Ser Thr Pro Thr Pro Gly Pro Glu Asp 
                405                 410                 415     


Gln Pro Leu Thr Pro Thr Gly Leu Asp Pro Gln Ser Gly Leu Gly Arg 
            420                 425                 430         


His Leu Gly 
        435 


<210>  827
<211>  424
<212>  PRT
<213>  Homo Sapiens

<400>  827

Gly Pro Phe Pro Lys Pro Thr Leu Trp Ala Glu Pro Gly Ser Val Ile 
1               5                   10                  15      


Ser Trp Gly Ser Pro Val Thr Ile Trp Cys Gln Gly Ser Leu Glu Ala 
            20                  25                  30          


Gln Glu Tyr Gln Leu Asp Lys Glu Gly Ser Pro Glu Pro Leu Asp Arg 
        35                  40                  45              


Asn Asn Pro Leu Glu Pro Lys Asn Lys Ala Arg Phe Ser Ile Pro Ser 
    50                  55                  60                  


Met Thr Gln His His Ala Gly Arg Tyr Arg Cys His Tyr Tyr Ser Ser 
65                  70                  75                  80  


Ala Gly Trp Ser Glu Pro Ser Asp Pro Leu Glu Leu Val Met Thr Gly 
                85                  90                  95      


Phe Tyr Asn Lys Pro Thr Leu Ser Ala Leu Pro Ser Pro Val Val Ala 
            100                 105                 110         


Ser Gly Gly Asn Met Thr Leu Arg Cys Gly Ser Gln Lys Gly Tyr His 
        115                 120                 125             


His Phe Val Leu Met Lys Glu Gly Glu His Gln Leu Pro Arg Thr Leu 
    130                 135                 140                 


Asp Ser Gln Gln Leu His Ser Gly Gly Phe Gln Ala Leu Phe Pro Val 
145                 150                 155                 160 


Gly Pro Val Thr Pro Ser His Arg Trp Arg Phe Thr Cys Tyr Tyr Tyr 
                165                 170                 175     


Tyr Thr Asn Thr Pro Arg Val Trp Ser His Pro Ser Asp Pro Leu Glu 
            180                 185                 190         


Ile Leu Pro Ser Gly Val Ser Arg Lys Pro Ser Leu Leu Thr Leu Gln 
        195                 200                 205             


Gly Pro Val Leu Ala Pro Gly Gln Ser Leu Thr Leu Gln Cys Gly Ser 
    210                 215                 220                 


Asp Val Gly Tyr Asp Arg Phe Val Leu Tyr Lys Glu Gly Glu Arg Asp 
225                 230                 235                 240 


Phe Leu Gln Arg Pro Gly Gln Gln Pro Gln Ala Gly Leu Ser Gln Ala 
                245                 250                 255     


Asn Phe Thr Leu Gly Pro Val Ser Pro Ser His Gly Gly Gln Tyr Arg 
            260                 265                 270         


Cys Tyr Gly Ala His Asn Leu Ser Ser Glu Trp Ser Ala Pro Ser Asp 
        275                 280                 285             


Pro Leu Asn Ile Leu Met Ala Gly Gln Ile Tyr Asp Thr Val Ser Leu 
    290                 295                 300                 


Ser Ala Gln Pro Gly Pro Thr Val Ala Ser Gly Glu Asn Val Thr Leu 
305                 310                 315                 320 


Leu Cys Gln Ser Arg Gly Tyr Phe Asp Thr Phe Leu Leu Thr Lys Glu 
                325                 330                 335     


Gly Ala Ala His Pro Pro Leu Arg Leu Arg Ser Met Tyr Gly Ala His 
            340                 345                 350         


Lys Tyr Gln Ala Glu Phe Pro Met Ser Pro Val Thr Ser Ala His Ala 
        355                 360                 365             


Gly Thr Tyr Arg Cys Tyr Gly Ser Tyr Ser Ser Asn Pro His Leu Leu 
    370                 375                 380                 


Ser Phe Pro Ser Glu Pro Leu Glu Leu Met Val Ser Gly His Ser Gly 
385                 390                 395                 400 


Gly Ser Ser Leu Pro Pro Thr Gly Pro Pro Ser Thr Pro Ala Ser His 
                405                 410                 415     


Ala Lys Asp Tyr Thr Val Glu Asn 
            420                 


<210>  828
<211>  520
<212>  PRT
<213>  Homo Sapiens

<400>  828

Cys Pro Pro Arg Cys Glu Cys Ser Ala Gln Asp Arg Ala Val Leu Cys 
1               5                   10                  15      


His Arg Lys Arg Phe Val Ala Val Pro Glu Gly Ile Pro Thr Glu Thr 
            20                  25                  30          


Arg Leu Leu Asp Leu Gly Lys Asn Arg Ile Lys Thr Leu Asn Gln Asp 
        35                  40                  45              


Glu Phe Ala Ser Phe Pro His Leu Glu Glu Leu Glu Leu Asn Glu Asn 
    50                  55                  60                  


Ile Val Ser Ala Val Glu Pro Gly Ala Phe Asn Asn Leu Phe Asn Leu 
65                  70                  75                  80  


Arg Thr Leu Gly Leu Arg Ser Asn Arg Leu Lys Leu Ile Pro Leu Gly 
                85                  90                  95      


Val Phe Thr Gly Leu Ser Asn Leu Thr Lys Leu Asp Ile Ser Glu Asn 
            100                 105                 110         


Lys Ile Val Ile Leu Leu Asp Tyr Met Phe Gln Asp Leu Tyr Asn Leu 
        115                 120                 125             


Lys Ser Leu Glu Val Gly Asp Asn Asp Leu Val Tyr Ile Ser His Arg 
    130                 135                 140                 


Ala Phe Ser Gly Leu Asn Ser Leu Glu Gln Leu Thr Leu Glu Lys Cys 
145                 150                 155                 160 


Asn Leu Thr Ser Ile Pro Thr Glu Ala Leu Ser His Leu His Gly Leu 
                165                 170                 175     


Ile Val Leu Arg Leu Arg His Leu Asn Ile Asn Ala Ile Arg Asp Tyr 
            180                 185                 190         


Ser Phe Lys Arg Leu Tyr Arg Leu Lys Val Leu Glu Ile Ser His Trp 
        195                 200                 205             


Pro Tyr Leu Asp Thr Met Thr Pro Asn Cys Leu Tyr Gly Leu Asn Leu 
    210                 215                 220                 


Thr Ser Leu Ser Ile Thr His Cys Asn Leu Thr Ala Val Pro Tyr Leu 
225                 230                 235                 240 


Ala Val Arg His Leu Val Tyr Leu Arg Phe Leu Asn Leu Ser Tyr Asn 
                245                 250                 255     


Pro Ile Ser Thr Ile Glu Gly Ser Met Leu His Glu Leu Leu Arg Leu 
            260                 265                 270         


Gln Glu Ile Gln Leu Val Gly Gly Gln Leu Ala Val Val Glu Pro Tyr 
        275                 280                 285             


Ala Phe Arg Gly Leu Asn Tyr Leu Arg Val Leu Asn Val Ser Gly Asn 
    290                 295                 300                 


Gln Leu Thr Thr Leu Glu Glu Ser Val Phe His Ser Val Gly Asn Leu 
305                 310                 315                 320 


Glu Thr Leu Ile Leu Asp Ser Asn Pro Leu Ala Cys Asp Cys Arg Leu 
                325                 330                 335     


Leu Trp Val Phe Arg Arg Arg Trp Arg Leu Asn Phe Asn Arg Gln Gln 
            340                 345                 350         


Pro Thr Cys Ala Thr Pro Glu Phe Val Gln Gly Lys Glu Phe Lys Asp 
        355                 360                 365             


Phe Pro Asp Val Leu Leu Pro Asn Tyr Phe Thr Cys Arg Arg Ala Arg 
    370                 375                 380                 


Ile Arg Asp Arg Lys Ala Gln Gln Val Phe Val Asp Glu Gly His Thr 
385                 390                 395                 400 


Val Gln Phe Val Cys Arg Ala Asp Gly Asp Pro Pro Pro Ala Ile Leu 
                405                 410                 415     


Trp Leu Ser Pro Arg Lys His Leu Val Ser Ala Lys Ser Asn Gly Arg 
            420                 425                 430         


Leu Thr Val Phe Pro Asp Gly Thr Leu Glu Val Arg Tyr Ala Gln Val 
        435                 440                 445             


Gln Asp Asn Gly Thr Tyr Leu Cys Ile Ala Ala Asn Ala Gly Gly Asn 
    450                 455                 460                 


Asp Ser Met Pro Ala His Leu His Val Arg Ser Tyr Ser Pro Asp Trp 
465                 470                 475                 480 


Pro His Gln Pro Asn Lys Thr Phe Ala Phe Ile Ser Asn Gln Pro Gly 
                485                 490                 495     


Glu Gly Glu Ala Asn Ser Thr Arg Ala Thr Val Pro Phe Pro Phe Asp 
            500                 505                 510         


Ile Lys Thr Leu Ile Ile Ala Thr 
        515                 520 


<210>  829
<211>  518
<212>  PRT
<213>  Homo Sapiens

<400>  829

Cys Pro Ala Arg Cys Glu Cys Ser Ala Gln Asn Lys Ser Val Ser Cys 
1               5                   10                  15      


His Arg Arg Arg Leu Ile Ala Ile Pro Glu Gly Ile Pro Ile Glu Thr 
            20                  25                  30          


Lys Ile Leu Asp Leu Ser Lys Asn Arg Leu Lys Ser Val Asn Pro Glu 
        35                  40                  45              


Glu Phe Ile Ser Tyr Pro Leu Leu Glu Glu Ile Asp Leu Ser Asp Asn 
    50                  55                  60                  


Ile Ile Ala Asn Val Glu Pro Gly Ala Phe Asn Asn Leu Phe Asn Leu 
65                  70                  75                  80  


Arg Ser Leu Arg Leu Lys Gly Asn Arg Leu Lys Leu Val Pro Leu Gly 
                85                  90                  95      


Val Phe Thr Gly Leu Ser Asn Leu Thr Lys Leu Asp Ile Ser Glu Asn 
            100                 105                 110         


Lys Ile Val Ile Leu Leu Asp Tyr Met Phe Gln Asp Leu His Asn Leu 
        115                 120                 125             


Lys Ser Leu Glu Val Gly Asp Asn Asp Leu Val Tyr Ile Ser His Arg 
    130                 135                 140                 


Ala Phe Ser Gly Leu Leu Ser Leu Glu Gln Leu Thr Leu Glu Lys Cys 
145                 150                 155                 160 


Asn Leu Thr Ala Val Pro Thr Glu Ala Leu Ser His Leu Arg Ser Leu 
                165                 170                 175     


Ile Ser Leu His Leu Lys His Leu Asn Ile Asn Asn Met Pro Val Tyr 
            180                 185                 190         


Ala Phe Lys Arg Leu Phe His Leu Lys His Leu Glu Ile Asp Tyr Trp 
        195                 200                 205             


Pro Leu Leu Asp Met Met Pro Ala Asn Ser Leu Tyr Gly Leu Asn Leu 
    210                 215                 220                 


Thr Ser Leu Ser Val Thr Asn Thr Asn Leu Ser Thr Val Pro Phe Leu 
225                 230                 235                 240 


Ala Phe Lys His Leu Val Tyr Leu Thr His Leu Asn Leu Ser Tyr Asn 
                245                 250                 255     


Pro Ile Ser Thr Ile Glu Ala Gly Met Phe Ser Asp Leu Ile Arg Leu 
            260                 265                 270         


Gln Glu Leu His Ile Val Gly Ala Gln Leu Arg Thr Ile Glu Pro His 
        275                 280                 285             


Ser Phe Gln Gly Leu Arg Phe Leu Arg Val Leu Asn Val Ser Gln Asn 
    290                 295                 300                 


Leu Leu Glu Thr Leu Glu Glu Asn Val Phe Ser Ser Pro Arg Ala Leu 
305                 310                 315                 320 


Glu Val Leu Ser Ile Asn Asn Asn Pro Leu Ala Cys Asp Cys Arg Leu 
                325                 330                 335     


Leu Trp Ile Leu Gln Arg Gln Pro Thr Leu Gln Phe Gly Gly Gln Gln 
            340                 345                 350         


Pro Met Cys Ala Gly Pro Asp Thr Ile Arg Glu Arg Ser Phe Lys Asp 
        355                 360                 365             


Phe His Ser Thr Ala Leu Ser Phe Tyr Phe Thr Cys Lys Lys Pro Lys 
    370                 375                 380                 


Ile Arg Glu Lys Lys Leu Gln His Leu Leu Val Asp Glu Gly Gln Thr 
385                 390                 395                 400 


Val Gln Leu Glu Cys Ser Ala Asp Gly Asp Pro Gln Pro Val Ile Ser 
                405                 410                 415     


Trp Val Thr Pro Arg Arg Arg Phe Ile Thr Thr Lys Ser Asn Gly Arg 
            420                 425                 430         


Ala Thr Val Leu Gly Asp Gly Thr Leu Glu Ile Arg Phe Ala Gln Asp 
        435                 440                 445             


Gln Asp Ser Gly Met Tyr Val Cys Ile Ala Ser Asn Ala Ala Gly Asn 
    450                 455                 460                 


Asp Thr Phe Thr Ala Ser Leu Thr Val Lys Gly Phe Ala Ser Asp Arg 
465                 470                 475                 480 


Phe Leu Tyr Ala Asn Arg Thr Pro Met Tyr Met Thr Asp Ser Asn Asp 
                485                 490                 495     


Thr Ile Ser Asn Gly Thr Asn Ala Asn Thr Phe Ser Leu Asp Leu Lys 
            500                 505                 510         


Thr Ile Leu Val Ser Thr 
        515             


<210>  830
<211>  507
<212>  PRT
<213>  Homo Sapiens

<400>  830

Cys Pro Ala Arg Cys Glu Cys Thr Val Gln Thr Arg Ala Val Ala Cys 
1               5                   10                  15      


Thr Arg Arg Arg Leu Thr Ala Val Pro Asp Gly Ile Pro Ala Glu Thr 
            20                  25                  30          


Arg Leu Leu Glu Leu Ser Arg Asn Arg Ile Arg Cys Leu Asn Pro Gly 
        35                  40                  45              


Asp Leu Ala Ala Leu Pro Ala Leu Glu Glu Leu Asp Leu Ser Glu Asn 
    50                  55                  60                  


Ala Ile Ala His Val Glu Pro Gly Ala Phe Ala Asn Leu Pro Arg Leu 
65                  70                  75                  80  


Arg Val Leu Arg Leu Arg Gly Asn Gln Leu Lys Leu Ile Pro Pro Gly 
                85                  90                  95      


Val Phe Thr Arg Leu Asp Asn Leu Thr Leu Leu Asp Leu Ser Glu Asn 
            100                 105                 110         


Lys Leu Val Ile Leu Leu Asp Tyr Thr Phe Gln Asp Leu His Ser Leu 
        115                 120                 125             


Arg Arg Leu Glu Val Gly Asp Asn Asp Leu Val Phe Val Ser Arg Arg 
    130                 135                 140                 


Ala Phe Ala Gly Leu Leu Ala Leu Glu Glu Leu Thr Leu Glu Arg Cys 
145                 150                 155                 160 


Asn Leu Thr Ala Leu Ser Gly Glu Ser Leu Gly His Leu Arg Ser Leu 
                165                 170                 175     


Gly Ala Leu Arg Leu Arg His Leu Ala Ile Ala Ser Leu Glu Asp Gln 
            180                 185                 190         


Asn Phe Arg Arg Leu Pro Gly Leu Leu His Leu Glu Ile Asp Asn Trp 
        195                 200                 205             


Pro Leu Leu Glu Glu Val Ala Ala Gly Ser Leu Arg Gly Leu Asn Leu 
    210                 215                 220                 


Thr Ser Leu Ser Val Thr His Thr Asn Ile Thr Ala Val Pro Ala Ala 
225                 230                 235                 240 


Ala Leu Arg His Gln Ala His Leu Thr Cys Leu Asn Leu Ser His Asn 
                245                 250                 255     


Pro Ile Ser Thr Val Pro Arg Gly Ser Phe Arg Asp Leu Val Arg Leu 
            260                 265                 270         


Arg Glu Leu His Leu Ala Gly Ala Leu Leu Ala Val Val Glu Pro Gln 
        275                 280                 285             


Ala Phe Leu Gly Leu Arg Gln Ile Arg Leu Leu Asn Leu Ser Asn Asn 
    290                 295                 300                 


Leu Leu Ser Thr Leu Glu Glu Ser Thr Phe His Ser Val Asn Thr Leu 
305                 310                 315                 320 


Glu Thr Leu Arg Val Asp Gly Asn Pro Leu Ala Cys Asp Cys Arg Leu 
                325                 330                 335     


Leu Trp Ile Val Gln Arg Arg Lys Thr Leu Asn Phe Asp Gly Arg Leu 
            340                 345                 350         


Pro Ala Cys Ala Thr Pro Ala Glu Val Arg Gly Asp Ala Leu Arg Asn 
        355                 360                 365             


Leu Pro Asp Ser Val Leu Phe Glu Tyr Phe Val Cys Arg Lys Pro Lys 
    370                 375                 380                 


Ile Arg Glu Arg Arg Leu Gln Arg Val Thr Ala Thr Ala Gly Glu Asp 
385                 390                 395                 400 


Val Arg Phe Leu Cys Arg Ala Glu Gly Glu Pro Ala Pro Thr Val Ala 
                405                 410                 415     


Trp Val Thr Pro Gln His Arg Pro Val Thr Ala Thr Ser Ala Gly Arg 
            420                 425                 430         


Ala Arg Val Leu Pro Gly Gly Thr Leu Glu Ile Gln Asp Ala Arg Pro 
        435                 440                 445             


Gln Asp Ser Gly Thr Tyr Thr Cys Val Ala Ser Asn Ala Gly Gly Asn 
    450                 455                 460                 


Asp Thr Tyr Phe Ala Thr Leu Thr Val Arg Pro Glu Pro Ala Ala Asn 
465                 470                 475                 480 


Arg Thr Pro Gly Glu Ala His Asn Glu Thr Leu Ala Ala Leu Arg Ala 
                485                 490                 495     


Pro Leu Asp Leu Thr Thr Ile Leu Val Ser Thr 
            500                 505         


<210>  831
<211>  505
<212>  PRT
<213>  Homo Sapiens

<400>  831

Gly Ser Cys Pro Ala Val Cys Asp Cys Thr Ser Gln Pro Gln Ala Val 
1               5                   10                  15      


Leu Cys Gly His Arg Gln Leu Glu Ala Val Pro Gly Gly Leu Pro Leu 
            20                  25                  30          


Asp Thr Glu Leu Leu Asp Leu Ser Gly Asn Arg Leu Trp Gly Leu Gln 
        35                  40                  45              


Gln Gly Met Leu Ser Arg Leu Ser Leu Leu Gln Glu Leu Asp Leu Ser 
    50                  55                  60                  


Tyr Asn Gln Leu Ser Thr Leu Glu Pro Gly Ala Phe His Gly Leu Gln 
65                  70                  75                  80  


Ser Leu Leu Thr Leu Arg Leu Gln Gly Asn Arg Leu Arg Ile Met Gly 
                85                  90                  95      


Pro Gly Val Phe Ser Gly Leu Ser Ala Leu Thr Leu Leu Asp Leu Arg 
            100                 105                 110         


Leu Asn Gln Ile Val Leu Phe Leu Asp Gly Ala Phe Gly Glu Leu Gly 
        115                 120                 125             


Ser Leu Gln Lys Leu Glu Val Gly Asp Asn His Leu Val Phe Val Ala 
    130                 135                 140                 


Pro Gly Ala Phe Ala Gly Leu Ala Lys Leu Ser Thr Leu Thr Leu Glu 
145                 150                 155                 160 


Arg Cys Asn Leu Ser Thr Val Pro Gly Leu Ala Leu Ala Arg Leu Pro 
                165                 170                 175     


Ala Leu Val Ala Leu Arg Leu Arg Glu Leu Asp Ile Gly Arg Leu Pro 
            180                 185                 190         


Ala Gly Ala Leu Arg Gly Leu Gly Gln Leu Lys Glu Leu Glu Ile His 
        195                 200                 205             


Leu Trp Pro Ser Leu Glu Ala Leu Asp Pro Gly Ser Leu Val Gly Leu 
    210                 215                 220                 


Asn Leu Ser Ser Leu Ala Ile Thr Arg Cys Asn Leu Ser Ser Val Pro 
225                 230                 235                 240 


Phe Gln Ala Leu Tyr His Leu Ser Phe Leu Arg Val Leu Asp Leu Ser 
                245                 250                 255     


Gln Asn Pro Ile Ser Ala Ile Pro Ala Arg Arg Leu Ser Pro Leu Val 
            260                 265                 270         


Arg Leu Gln Glu Leu Arg Leu Ser Gly Ala Cys Leu Thr Ser Ile Ala 
        275                 280                 285             


Ala His Ala Phe His Gly Leu Thr Ala Phe His Leu Leu Asp Val Ala 
    290                 295                 300                 


Asp Asn Ala Leu Gln Thr Leu Glu Glu Thr Ala Phe Pro Ser Pro Asp 
305                 310                 315                 320 


Lys Leu Val Thr Leu Arg Leu Ser Gly Asn Pro Leu Thr Cys Asp Cys 
                325                 330                 335     


Arg Leu Leu Trp Leu Leu Arg Leu Arg Arg His Leu Asp Phe Gly Met 
            340                 345                 350         


Ser Pro Pro Ala Cys Ala Gly Pro His His Val Gln Gly Lys Ser Leu 
        355                 360                 365             


Lys Glu Phe Ser Asp Ile Leu Pro Pro Gly His Phe Thr Cys Lys Pro 
    370                 375                 380                 


Ala Leu Ile Arg Lys Ser Gly Pro Arg Trp Val Ile Ala Glu Glu Gly 
385                 390                 395                 400 


Gly His Ala Val Phe Ser Cys Ser Gly Asp Gly Asp Pro Ala Pro Thr 
                405                 410                 415     


Val Ser Trp Met Arg Pro His Gly Ala Trp Leu Gly Arg Ala Gly Arg 
            420                 425                 430         


Val Arg Val Leu Glu Asp Gly Thr Leu Glu Ile Arg Ser Val Gln Leu 
        435                 440                 445             


Arg Asp Arg Gly Ala Tyr Val Cys Val Val Ser Asn Val Ala Gly Asn 
    450                 455                 460                 


Asp Ser Leu Arg Thr Trp Leu Glu Val Ile Gln Val Glu Pro Pro Asn 
465                 470                 475                 480 


Gly Thr Leu Ser Asp Pro Asn Ile Thr Val Pro Gly Ile Pro Gly Pro 
                485                 490                 495     


Phe Phe Leu Asp Ser Arg Gly Val Ala 
            500                 505 


<210>  832
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  832

Glu Val Trp Pro Pro Gln Leu Gln Glu Gln Ala Pro Met Ala Gly Ala 
1               5                   10                  15      


Leu Asn Arg Lys Glu Ser Phe Leu Leu Leu Ser Leu His Asn Arg Leu 
            20                  25                  30          


Arg Ser Trp Val Gln Pro Pro Ala Ala Asp Met Arg Arg Leu Asp Trp 
        35                  40                  45              


Ser Asp Ser Leu Ala Gln Leu Ala Gln Ala Arg Ala Ala Leu Cys Gly 
    50                  55                  60                  


Thr Pro Thr Pro Ser Leu Ala Ser Gly Leu Trp Arg Thr Leu Gln Val 
65                  70                  75                  80  


Gly Trp Asn Met Gln Leu Leu Pro Ala Gly Leu Val Ser Phe Val Glu 
                85                  90                  95      


Val Val Ser Leu Trp Phe Ala Glu Gly Gln Arg Tyr Ser His Ala Ala 
            100                 105                 110         


Gly Glu Cys Ala Arg Asn Ala Thr Cys Thr His Tyr Thr Gln Leu Val 
        115                 120                 125             


Trp Ala Thr Ser Ser Gln Leu Gly Cys Gly Arg His Leu Cys Ser Ala 
    130                 135                 140                 


Gly Gln Ala Ala Ile Glu Ala Phe Val Cys Ala Tyr Ser Pro Arg Gly 
145                 150                 155                 160 


Asn Trp Glu Val Asn Gly Lys Thr Ile Val Pro Tyr Lys Lys Gly Ala 
                165                 170                 175     


Trp Cys Ser Leu Cys Thr Ala Ser Val Ser Gly Cys Phe Lys Ala Trp 
            180                 185                 190         


Asp His Ala Gly Gly Leu Cys Glu Val Pro Arg Asn Pro Cys Arg Met 
        195                 200                 205             


Ser Cys Gln Asn His Gly Arg Leu Asn Ile Ser Thr Cys His Cys His 
    210                 215                 220                 


Cys Pro Pro Gly Tyr Thr Gly Arg Tyr Cys Gln Val Arg Cys Ser Leu 
225                 230                 235                 240 


Gln Cys Val His Gly Arg Leu Arg Glu Glu Glu Cys Ser Cys Val Cys 
                245                 250                 255     


Asp Ile Gly Tyr Gly Gly Ala Gln Cys Ala Thr Lys Val His Phe Pro 
            260                 265                 270         


Phe His Thr Cys Asp Leu Arg Ile Asp Gly Asp Cys Phe Met Val Ser 
        275                 280                 285             


Ser Glu Ala Asp Thr Tyr Tyr Arg Ala Arg Met Lys Cys Gln Arg Lys 
    290                 295                 300                 


Gly Gly Val Leu Ala Gln Ile Lys Ser Gln Lys Val Gln Asp Ile Leu 
305                 310                 315                 320 


Ala Phe Tyr Leu Gly Arg Leu Glu Thr Thr Asn Glu Val Ile Asp Ser 
                325                 330                 335     


Asp Phe Glu Thr Arg Asn Phe Trp Ile Gly Leu Thr Tyr Lys Thr Ala 
            340                 345                 350         


Lys Asp Ser Phe Arg Trp Ala Thr Gly Glu His Gln Ala Phe Thr Ser 
        355                 360                 365             


Phe Ala Phe Gly Gln Pro Asp Asn His Gly Phe Gly Asn Cys Val Glu 
    370                 375                 380                 


Leu Gln Ala Ser Ala Ala Phe Asn Trp Asn Asn Gln Arg Cys Lys Thr 
385                 390                 395                 400 


Arg Asn Arg Tyr Ile Cys Gln Phe Ala Gln Glu His Ile Ser Arg Trp 
                405                 410                 415     


Gly Pro Gly Ser 
            420 


<210>  833
<211>  249
<212>  PRT
<213>  Homo Sapiens

<400>  833

Asp Asp Pro Tyr Asn Pro Tyr Lys Tyr Ser Asp Asp Asn Pro Tyr Tyr 
1               5                   10                  15      


Asn Tyr Tyr Asp Thr Tyr Glu Arg Pro Arg Pro Gly Gly Arg Tyr Arg 
            20                  25                  30          


Pro Gly Tyr Gly Thr Gly Tyr Phe Gln Tyr Gly Leu Pro Asp Leu Val 
        35                  40                  45              


Ala Asp Pro Tyr Tyr Ile Gln Ala Ser Thr Tyr Val Gln Lys Met Ser 
    50                  55                  60                  


Met Tyr Asn Leu Arg Cys Ala Ala Glu Glu Asn Cys Leu Ala Ser Thr 
65                  70                  75                  80  


Ala Tyr Arg Ala Asp Val Arg Asp Tyr Asp His Arg Val Leu Leu Arg 
                85                  90                  95      


Phe Pro Gln Arg Val Lys Asn Gln Gly Thr Ser Asp Phe Leu Pro Ser 
            100                 105                 110         


Arg Pro Arg Tyr Ser Trp Glu Trp His Ser Cys His Gln His Tyr His 
        115                 120                 125             


Ser Met Asp Glu Phe Ser His Tyr Asp Leu Leu Asp Ala Asn Thr Gln 
    130                 135                 140                 


Arg Arg Val Ala Glu Gly His Lys Ala Ser Phe Cys Leu Glu Asp Thr 
145                 150                 155                 160 


Ser Cys Asp Tyr Gly Tyr His Arg Arg Phe Ala Cys Thr Ala His Thr 
                165                 170                 175     


Gln Gly Leu Ser Pro Gly Cys Tyr Asp Thr Tyr Gly Ala Asp Ile Asp 
            180                 185                 190         


Cys Gln Trp Ile Asp Ile Thr Asp Val Lys Pro Gly Asn Tyr Ile Leu 
        195                 200                 205             


Lys Val Ser Val Asn Pro Ser Tyr Leu Val Pro Glu Ser Asp Tyr Thr 
    210                 215                 220                 


Asn Asn Val Val Arg Cys Asp Ile Arg Tyr Thr Gly His His Ala Tyr 
225                 230                 235                 240 


Ala Ser Gly Cys Thr Ile Ser Pro Tyr 
                245                 


<210>  834
<211>  480
<212>  PRT
<213>  Homo Sapiens

<400>  834

Arg Gln Ala Pro Ser Leu Pro Leu Pro Gly Arg Val Gly Ser Asp Thr 
1               5                   10                  15      


Val Arg Gly Gln Ala Arg His Pro Phe Gly Phe Gly Gln Val Pro Asp 
            20                  25                  30          


Asn Trp Arg Glu Val Ala Val Gly Asp Ser Thr Gly Met Ala Arg Ala 
        35                  40                  45              


Arg Thr Ser Val Ser Gln Gln Arg His Gly Asp Ser Ala Ser Ser Val 
    50                  55                  60                  


Ser Ala Ser Ala Phe Ala Ser Thr Tyr Arg Gln Gln Pro Ser Tyr Pro 
65                  70                  75                  80  


Gln Gln Phe Pro Tyr Pro Gln Ala Pro Phe Val Ser Gln Tyr Glu Asn 
                85                  90                  95      


Tyr Asp Pro Ala Ser Arg Thr Tyr Asp Gln Gly Phe Val Tyr Tyr Arg 
            100                 105                 110         


Pro Ala Gly Gly Gly Val Gly Ala Gly Ala Ala Ala Val Ala Ser Ala 
        115                 120                 125             


Gly Val Ile Tyr Pro Tyr Gln Pro Arg Ala Arg Tyr Glu Glu Tyr Gly 
    130                 135                 140                 


Gly Gly Glu Glu Leu Pro Glu Tyr Pro Pro Gln Gly Phe Tyr Pro Ala 
145                 150                 155                 160 


Pro Glu Arg Pro Tyr Val Pro Pro Pro Pro Pro Pro Pro Asp Gly Leu 
                165                 170                 175     


Asp Arg Arg Tyr Ser His Ser Leu Tyr Ser Glu Gly Thr Pro Gly Phe 
            180                 185                 190         


Glu Gln Ala Tyr Pro Asp Pro Gly Pro Glu Ala Ala Gln Ala His Gly 
        195                 200                 205             


Gly Asp Pro Arg Leu Gly Trp Tyr Pro Pro Tyr Ala Asn Pro Pro Pro 
    210                 215                 220                 


Glu Ala Tyr Gly Pro Pro Arg Ala Leu Glu Pro Pro Tyr Leu Pro Val 
225                 230                 235                 240 


Arg Ser Ser Asp Thr Pro Pro Pro Gly Gly Glu Arg Asn Gly Ala Gln 
                245                 250                 255     


Gln Gly Arg Leu Ser Val Gly Ser Val Tyr Arg Pro Asn Gln Asn Gly 
            260                 265                 270         


Arg Gly Leu Pro Asp Leu Val Pro Asp Pro Asn Tyr Val Gln Ala Ser 
        275                 280                 285             


Thr Tyr Val Gln Arg Ala His Leu Tyr Ser Leu Arg Cys Ala Ala Glu 
    290                 295                 300                 


Glu Lys Cys Leu Ala Ser Thr Ala Tyr Ala Pro Glu Ala Thr Asp Tyr 
305                 310                 315                 320 


Asp Val Arg Val Leu Leu Arg Phe Pro Gln Arg Val Lys Asn Gln Gly 
                325                 330                 335     


Thr Ala Asp Phe Leu Pro Asn Arg Pro Arg His Thr Trp Glu Trp His 
            340                 345                 350         


Ser Cys His Gln His Tyr His Ser Met Asp Glu Phe Ser His Tyr Asp 
        355                 360                 365             


Leu Leu Asp Ala Ala Thr Gly Lys Lys Val Ala Glu Gly His Lys Ala 
    370                 375                 380                 


Ser Phe Cys Leu Glu Asp Ser Thr Cys Asp Phe Gly Asn Leu Lys Arg 
385                 390                 395                 400 


Tyr Ala Cys Thr Ser His Thr Gln Gly Leu Ser Pro Gly Cys Tyr Asp 
                405                 410                 415     


Thr Tyr Asn Ala Asp Ile Asp Cys Gln Trp Ile Asp Ile Thr Asp Val 
            420                 425                 430         


Gln Pro Gly Asn Tyr Ile Leu Lys Val His Val Asn Pro Lys Tyr Ile 
        435                 440                 445             


Val Leu Glu Ser Asp Phe Thr Asn Asn Val Val Arg Cys Asn Ile His 
    450                 455                 460                 


Tyr Thr Gly Arg Tyr Val Ser Ala Thr Asn Cys Lys Ile Val Gln Ser 
465                 470                 475                 480 


<210>  835
<211>  629
<212>  PRT
<213>  Homo Sapiens

<400>  835

Gly Asn Leu Pro Gly Val His Cys Gly Pro Ser Ser Gly Ala Gly Pro 
1               5                   10                  15      


Gly Phe Gly Pro Gly Ser Trp Ser Arg Ser Leu Asp Arg Ala Leu Glu 
            20                  25                  30          


Glu Ala Ala Val Thr Gly Val Leu Ser Leu Ser Gly Arg Lys Leu Arg 
        35                  40                  45              


Glu Phe Pro Arg Gly Ala Ala Asn His Asp Leu Thr Asp Thr Thr Arg 
    50                  55                  60                  


Ala Asp Leu Ser Arg Asn Arg Leu Ser Glu Ile Pro Ile Glu Ala Cys 
65                  70                  75                  80  


His Phe Val Ser Leu Glu Asn Leu Asn Leu Tyr Gln Asn Cys Ile Arg 
                85                  90                  95      


Tyr Ile Pro Glu Ala Ile Leu Asn Leu Gln Ala Leu Thr Phe Leu Asn 
            100                 105                 110         


Ile Ser Arg Asn Gln Leu Ser Thr Leu Pro Val His Leu Cys Asn Leu 
        115                 120                 125             


Pro Leu Lys Val Leu Ile Ala Ser Asn Asn Lys Leu Val Ser Leu Pro 
    130                 135                 140                 


Glu Glu Ile Gly His Leu Arg His Leu Met Glu Leu Asp Val Ser Cys 
145                 150                 155                 160 


Asn Glu Ile Gln Thr Ile Pro Ser Gln Ile Gly Asn Leu Glu Ala Leu 
                165                 170                 175     


Arg Asp Leu Asn Val Arg Arg Asn His Leu Val His Leu Pro Glu Glu 
            180                 185                 190         


Leu Ala Glu Leu Pro Leu Ile Arg Leu Asp Phe Ser Cys Asn Lys Ile 
        195                 200                 205             


Thr Thr Ile Pro Val Cys Tyr Arg Asn Leu Arg His Leu Gln Thr Ile 
    210                 215                 220                 


Thr Leu Asp Asn Asn Pro Leu Gln Ser Pro Pro Ala Gln Ile Cys Ile 
225                 230                 235                 240 


Lys Gly Lys Val His Ile Phe Lys Tyr Leu Asn Ile Gln Ala Cys Lys 
                245                 250                 255     


Ile Ala Pro Asp Leu Pro Asp Tyr Asp Arg Arg Pro Leu Gly Phe Gly 
            260                 265                 270         


Ser Cys His Glu Glu Leu Tyr Ser Ser Arg Pro Tyr Gly Ala Leu Asp 
        275                 280                 285             


Ser Gly Phe Asn Ser Val Asp Ser Gly Asp Lys Arg Trp Ser Gly Asn 
    290                 295                 300                 


Glu Pro Thr Asp Glu Phe Ser Asp Leu Pro Leu Arg Val Ala Glu Ile 
305                 310                 315                 320 


Thr Lys Glu Gln Arg Leu Arg Arg Glu Ser Gln Tyr Gln Glu Asn Arg 
                325                 330                 335     


Gly Ser Leu Val Val Thr Asn Gly Gly Val Glu His Asp Leu Asp Gln 
            340                 345                 350         


Ile Asp Tyr Ile Asp Ser Cys Thr Ala Glu Glu Glu Glu Ala Glu Val 
        355                 360                 365             


Arg Gln Pro Lys Gly Pro Asp Pro Asp Ser Leu Ser Ser Gln Phe Met 
    370                 375                 380                 


Ala Tyr Ile Glu Gln Arg Arg Ile Ser His Glu Gly Ser Pro Val Lys 
385                 390                 395                 400 


Pro Val Ala Ile Arg Glu Phe Gln Lys Thr Glu Asp Met Arg Arg Tyr 
                405                 410                 415     


Leu His Gln Asn Arg Val Pro Ala Glu Pro Ser Ser Leu Leu Ser Leu 
            420                 425                 430         


Ser Ala Ser His Asn Gln Leu Ser His Thr Asp Leu Glu Leu His Gln 
        435                 440                 445             


Arg Arg Glu Gln Leu Val Glu Arg Thr Arg Arg Glu Ala Gln Leu Ala 
    450                 455                 460                 


Ala Leu Gln Tyr Glu Glu Glu Lys Ile Arg Thr Lys Gln Ile Gln Arg 
465                 470                 475                 480 


Asp Ala Val Leu Asp Phe Val Lys Gln Lys Ala Ser Gln Ser Pro Gln 
                485                 490                 495     


Lys Gln His Pro Leu Leu Asp Gly Val Asp Gly Glu Cys Pro Phe Pro 
            500                 505                 510         


Ser Arg Arg Ser Gln His Thr Asp Asp Ser Ala Leu Cys Met Ser Leu 
        515                 520                 525             


Ser Gly Leu Asn Gln Val Gly Cys Ala Ala Thr Leu Pro His Ser Ser 
    530                 535                 540                 


Ala Phe Thr Pro Leu Lys Ser Asp Asp Arg Pro Asn Ala Leu Leu Ser 
545                 550                 555                 560 


Ser Pro Ala Thr Glu Thr Val His His Ser Pro Ala Tyr Ser Phe Pro 
                565                 570                 575     


Ala Ala Ile Gln Arg Asn Gln Pro Gln Arg Pro Glu Ser Phe Leu Phe 
            580                 585                 590         


Arg Ala Gly Val Arg Ala Glu Thr Asn Lys Gly His Ala Ser Pro Leu 
        595                 600                 605             


Pro Pro Ser Ala Ala Pro Thr Thr Asp Ser Thr Asp Ser Ile Thr Gly 
    610                 615                 620                 


Gln Asn Ser Arg Gln 
625                 


<210>  836
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  836

Pro Leu Ile Thr Arg Gln Ala Gly Gly Arg Ala Leu Val Val Glu Gly 
1               5                   10                  15      


Gln Ala Val Ser Leu Arg Cys Arg Ala Val Gly Asp Pro Glu Pro Val 
            20                  25                  30          


Val His Trp Val Ala Pro Asp Gly Arg Leu Leu Gly Asn Ser Ser Arg 
        35                  40                  45              


Thr Arg Val Arg Gly Asp Gly Thr Leu Asp Val Thr Ile Thr Thr Leu 
    50                  55                  60                  


Arg Asp Ser Gly Thr Phe Thr Cys Ile Ala Ser Asn Ala Ala Gly Glu 
65                  70                  75                  80  


Ala Thr Ala Pro Val Glu Val Cys Val Val Pro Leu Pro Leu Met Ala 
                85                  90                  95      


Pro Pro Pro Ala Ala Pro Pro Pro Leu Thr Glu Pro Gly Ser Ser Asp 
            100                 105                 110         


Ile Ala Thr Pro Gly Arg Pro Gly Ala Asn Asp Ser Ala Ala Glu Arg 
        115                 120                 125             


Arg Leu Val Ala Ala Glu Leu Thr Ser Asn Ser Val Leu Ile Arg Trp 
    130                 135                 140                 


Pro Ala Gln Arg Pro Val Pro Gly Ile Arg Met Tyr Gln Val Gln Tyr 
145                 150                 155                 160 


Asn Ser Ser Val Asp Asp Ser Leu Val Tyr Arg Met Ile Pro Ser Thr 
                165                 170                 175     


Ser Gln Thr Phe Leu Val Asn Asp Leu Ala Ala Gly Arg Ala Tyr Asp 
            180                 185                 190         


Leu Cys Val Leu Ala Val Tyr Asp Asp Gly Ala Thr Ala Leu Pro Ala 
        195                 200                 205             


Thr Arg Val Val Gly Cys Val Gln Phe Thr Thr Ala Gly Asp Pro Ala 
    210                 215                 220                 


Pro Cys Arg Pro Leu Arg Ala His Phe Leu Gly Gly Thr Met 
225                 230                 235             


<210>  837
<211>  514
<212>  PRT
<213>  Homo Sapiens

<400>  837

Cys Pro Lys Tyr Cys Val Cys Gln Asn Leu Ser Glu Ser Leu Gly Thr 
1               5                   10                  15      


Leu Cys Pro Ser Lys Gly Leu Leu Phe Val Pro Pro Asp Ile Asp Arg 
            20                  25                  30          


Arg Thr Val Glu Leu Arg Leu Gly Gly Asn Phe Ile Ile His Ile Ser 
        35                  40                  45              


Arg Gln Asp Phe Ala Asn Met Thr Gly Leu Val Asp Leu Thr Leu Ser 
    50                  55                  60                  


Arg Asn Thr Ile Ser His Ile Gln Pro Phe Ser Phe Leu Asp Leu Glu 
65                  70                  75                  80  


Ser Leu Arg Ser Leu His Leu Asp Ser Asn Arg Leu Pro Ser Leu Gly 
                85                  90                  95      


Glu Asp Thr Leu Arg Gly Leu Val Asn Leu Gln His Leu Ile Val Asn 
            100                 105                 110         


Asn Asn Gln Leu Gly Gly Ile Ala Asp Glu Ala Phe Glu Asp Phe Leu 
        115                 120                 125             


Leu Thr Leu Glu Asp Leu Asp Leu Ser Tyr Asn Asn Leu His Gly Leu 
    130                 135                 140                 


Pro Trp Asp Ser Val Arg Arg Met Val Asn Leu His Gln Leu Ser Leu 
145                 150                 155                 160 


Asp His Asn Leu Leu Asp His Ile Ala Glu Gly Thr Phe Ala Asp Leu 
                165                 170                 175     


Gln Lys Leu Ala Arg Leu Asp Leu Thr Ser Asn Arg Leu Gln Lys Leu 
            180                 185                 190         


Pro Pro Asp Pro Ile Phe Ala Arg Ser Gln Ala Ser Ala Leu Thr Ala 
        195                 200                 205             


Thr Pro Phe Ala Pro Pro Leu Ser Phe Ser Phe Gly Gly Asn Pro Leu 
    210                 215                 220                 


His Cys Asn Cys Glu Leu Leu Trp Leu Arg Arg Leu Glu Arg Asp Asp 
225                 230                 235                 240 


Asp Leu Glu Thr Cys Gly Ser Pro Gly Gly Leu Lys Gly Arg Tyr Phe 
                245                 250                 255     


Trp His Val Arg Glu Glu Glu Phe Val Cys Glu Pro Pro Leu Ile Thr 
            260                 265                 270         


Gln His Thr His Lys Leu Leu Val Leu Glu Gly Gln Ala Ala Thr Leu 
        275                 280                 285             


Lys Cys Lys Ala Ile Gly Asp Pro Ser Pro Leu Ile His Trp Val Ala 
    290                 295                 300                 


Pro Asp Asp Arg Leu Val Gly Asn Ser Ser Arg Thr Ala Val Tyr Asp 
305                 310                 315                 320 


Asn Gly Thr Leu Asp Ile Phe Ile Thr Thr Ser Gln Asp Ser Gly Ala 
                325                 330                 335     


Phe Thr Cys Ile Ala Ala Asn Ala Ala Gly Glu Ala Thr Ala Met Val 
            340                 345                 350         


Glu Val Ser Ile Val Gln Leu Pro His Leu Ser Asn Ser Thr Ser Arg 
        355                 360                 365             


Thr Ala Pro Pro Lys Ser Arg Leu Ser Asp Ile Thr Gly Ser Ser Lys 
    370                 375                 380                 


Thr Ser Arg Gly Gly Gly Gly Ser Gly Gly Gly Glu Pro Pro Lys Ser 
385                 390                 395                 400 


Pro Pro Glu Arg Ala Val Leu Val Ser Glu Val Thr Thr Thr Ser Ala 
                405                 410                 415     


Leu Val Lys Trp Ser Val Ser Lys Ser Ala Pro Arg Val Lys Met Tyr 
            420                 425                 430         


Gln Leu Gln Tyr Asn Cys Ser Asp Asp Glu Val Leu Ile Tyr Arg Met 
        435                 440                 445             


Ile Pro Ala Ser Asn Lys Ala Phe Val Val Asn Asn Leu Val Ser Gly 
    450                 455                 460                 


Thr Gly Tyr Asp Leu Cys Val Leu Ala Met Trp Asp Asp Thr Ala Thr 
465                 470                 475                 480 


Thr Leu Thr Ala Thr Asn Ile Val Gly Cys Ala Gln Phe Phe Thr Lys 
                485                 490                 495     


Ala Asp Tyr Pro Gln Cys Gln Ser Met His Ser Gln Ile Leu Gly Gly 
            500                 505                 510         


Thr Met 
        


<210>  838
<211>  523
<212>  PRT
<213>  Homo Sapiens

<400>  838

Ser Ser Pro Pro Gln Ser Ala Thr Pro Ser Pro Cys Pro Arg Arg Cys 
1               5                   10                  15      


Arg Cys Gln Thr Gln Ser Leu Pro Leu Ser Val Leu Cys Pro Gly Ala 
            20                  25                  30          


Gly Leu Leu Phe Val Pro Pro Ser Leu Asp Arg Arg Ala Ala Glu Leu 
        35                  40                  45              


Arg Leu Ala Asp Asn Phe Ile Ala Ser Val Arg Arg Arg Asp Leu Ala 
    50                  55                  60                  


Asn Met Thr Gly Leu Leu His Leu Ser Leu Ser Arg Asn Thr Ile Arg 
65                  70                  75                  80  


His Val Ala Ala Gly Ala Phe Ala Asp Leu Arg Ala Leu Arg Ala Leu 
                85                  90                  95      


His Leu Asp Gly Asn Arg Leu Thr Ser Leu Gly Glu Gly Gln Leu Arg 
            100                 105                 110         


Gly Leu Val Asn Leu Arg His Leu Ile Leu Ser Asn Asn Gln Leu Ala 
        115                 120                 125             


Ala Leu Ala Ala Gly Ala Leu Asp Asp Cys Ala Glu Thr Leu Glu Asp 
    130                 135                 140                 


Leu Asp Leu Ser Tyr Asn Asn Leu Glu Gln Leu Pro Trp Glu Ala Leu 
145                 150                 155                 160 


Gly Arg Leu Gly Asn Val Asn Thr Leu Gly Leu Asp His Asn Leu Leu 
                165                 170                 175     


Ala Ser Val Pro Ala Gly Ala Phe Ser Arg Leu His Lys Leu Ala Arg 
            180                 185                 190         


Leu Asp Met Thr Ser Asn Arg Leu Thr Thr Ile Pro Pro Asp Pro Leu 
        195                 200                 205             


Phe Ser Arg Leu Pro Leu Leu Ala Arg Pro Arg Gly Ser Pro Ala Ser 
    210                 215                 220                 


Ala Leu Val Leu Ala Phe Gly Gly Asn Pro Leu His Cys Asn Cys Glu 
225                 230                 235                 240 


Leu Val Trp Leu Arg Arg Leu Ala Arg Glu Asp Asp Leu Glu Ala Cys 
                245                 250                 255     


Ala Ser Pro Pro Ala Leu Gly Gly Arg Tyr Phe Trp Ala Val Gly Glu 
            260                 265                 270         


Glu Glu Phe Val Cys Glu Pro Pro Val Val Thr His Arg Ser Pro Pro 
        275                 280                 285             


Leu Ala Val Pro Ala Gly Arg Pro Ala Ala Leu Arg Cys Arg Ala Val 
    290                 295                 300                 


Gly Asp Pro Glu Pro Arg Val Arg Trp Val Ser Pro Gln Gly Arg Leu 
305                 310                 315                 320 


Leu Gly Asn Ser Ser Arg Ala Arg Ala Phe Pro Asn Gly Thr Leu Glu 
                325                 330                 335     


Leu Leu Val Thr Glu Pro Gly Asp Gly Gly Ile Phe Thr Cys Ile Ala 
            340                 345                 350         


Ala Asn Ala Ala Gly Glu Ala Thr Ala Ala Val Glu Leu Thr Val Gly 
        355                 360                 365             


Pro Pro Pro Pro Pro Gln Leu Ala Asn Ser Thr Ser Cys Asp Pro Pro 
    370                 375                 380                 


Arg Asp Gly Asp Pro Asp Ala Leu Thr Pro Pro Ser Ala Ala Ser Ala 
385                 390                 395                 400 


Ser Ala Lys Val Ala Asp Thr Gly Pro Pro Thr Asp Arg Gly Val Gln 
                405                 410                 415     


Val Thr Glu His Gly Ala Thr Ala Ala Leu Val Gln Trp Pro Asp Gln 
            420                 425                 430         


Arg Pro Ile Pro Gly Ile Arg Met Tyr Gln Ile Gln Tyr Asn Ser Ser 
        435                 440                 445             


Ala Asp Asp Ile Leu Val Tyr Arg Met Ile Pro Ala Glu Ser Arg Ser 
    450                 455                 460                 


Phe Leu Leu Thr Asp Leu Ala Ser Gly Arg Thr Tyr Asp Leu Cys Val 
465                 470                 475                 480 


Leu Ala Val Tyr Glu Asp Ser Ala Thr Gly Leu Thr Ala Thr Arg Pro 
                485                 490                 495     


Val Gly Cys Ala Arg Phe Ser Thr Glu Pro Ala Leu Arg Pro Cys Gly 
            500                 505                 510         


Ala Pro His Ala Pro Phe Leu Gly Gly Thr Met 
        515                 520             


<210>  839
<211>  502
<212>  PRT
<213>  Homo Sapiens

<400>  839

Cys Pro Leu Pro Cys Val Cys Gln Asn Leu Ser Glu Ser Leu Ser Thr 
1               5                   10                  15      


Leu Cys Ala His Arg Gly Leu Leu Phe Val Pro Pro Asn Val Asp Arg 
            20                  25                  30          


Arg Thr Val Glu Leu Arg Leu Ala Asp Asn Phe Ile Gln Ala Leu Gly 
        35                  40                  45              


Pro Pro Asp Phe Arg Asn Met Thr Gly Leu Val Asp Leu Thr Leu Ser 
    50                  55                  60                  


Arg Asn Ala Ile Thr Arg Ile Gly Ala Arg Ala Phe Gly Asp Leu Glu 
65                  70                  75                  80  


Ser Leu Arg Ser Leu His Leu Asp Gly Asn Arg Leu Val Glu Leu Gly 
                85                  90                  95      


Thr Gly Ser Leu Arg Gly Pro Val Asn Leu Gln His Leu Ile Leu Ser 
            100                 105                 110         


Gly Asn Gln Leu Gly Arg Ile Ala Pro Gly Ala Phe Asp Asp Phe Leu 
        115                 120                 125             


Glu Ser Leu Glu Asp Leu Asp Leu Ser Tyr Asn Asn Leu Arg Gln Val 
    130                 135                 140                 


Pro Trp Ala Gly Ile Gly Ala Met Pro Ala Leu His Thr Leu Asn Leu 
145                 150                 155                 160 


Asp His Asn Leu Ile Asp Ala Leu Pro Pro Gly Ala Phe Ala Gln Leu 
                165                 170                 175     


Gly Gln Leu Ser Arg Leu Asp Leu Thr Ser Asn Arg Leu Ala Thr Leu 
            180                 185                 190         


Ala Pro Asp Pro Leu Phe Ser Arg Gly Arg Asp Ala Glu Ala Ser Pro 
        195                 200                 205             


Ala Pro Leu Val Leu Ser Phe Ser Gly Asn Pro Leu His Cys Asn Cys 
    210                 215                 220                 


Glu Leu Leu Trp Leu Arg Arg Leu Ala Arg Pro Asp Asp Leu Glu Thr 
225                 230                 235                 240 


Cys Ala Ser Pro Pro Gly Leu Ala Gly Arg Tyr Phe Trp Ala Val Pro 
                245                 250                 255     


Glu Gly Glu Phe Ser Cys Glu Pro Pro Leu Ile Ala Arg His Thr Gln 
            260                 265                 270         


Arg Leu Trp Val Leu Glu Gly Gln Arg Ala Thr Leu Arg Cys Arg Ala 
        275                 280                 285             


Leu Gly Asp Pro Ala Pro Thr Met His Trp Val Gly Pro Asp Asp Arg 
    290                 295                 300                 


Leu Val Gly Asn Ser Ser Arg Ala Arg Ala Phe Pro Asn Gly Thr Leu 
305                 310                 315                 320 


Glu Ile Gly Val Thr Gly Ala Gly Asp Ala Gly Gly Tyr Thr Cys Ile 
                325                 330                 335     


Ala Thr Asn Pro Ala Gly Glu Ala Thr Ala Arg Val Glu Leu Arg Val 
            340                 345                 350         


Leu Ala Leu Pro His Gly Gly Asn Ser Ser Ala Glu Gly Gly Arg Pro 
        355                 360                 365             


Gly Pro Ser Asp Ile Ala Ala Ser Ala Arg Thr Ala Ala Glu Gly Glu 
    370                 375                 380                 


Gly Thr Leu Glu Ser Glu Pro Ala Val Gln Val Thr Glu Val Thr Ala 
385                 390                 395                 400 


Thr Ser Gly Leu Val Ser Trp Gly Pro Gly Arg Pro Ala Asp Pro Val 
                405                 410                 415     


Trp Met Phe Gln Ile Gln Tyr Asn Ser Ser Glu Asp Glu Thr Leu Ile 
            420                 425                 430         


Tyr Arg Ile Val Pro Ala Ser Ser His His Phe Leu Leu Lys His Leu 
        435                 440                 445             


Val Pro Gly Ala Asp Tyr Asp Leu Cys Leu Leu Ala Leu Ser Pro Ala 
    450                 455                 460                 


Ala Gly Pro Ser Asp Leu Thr Ala Thr Arg Leu Leu Gly Cys Ala His 
465                 470                 475                 480 


Phe Ser Thr Leu Pro Ala Ser Pro Leu Cys His Ala Leu Gln Ala His 
                485                 490                 495     


Val Leu Gly Gly Thr Leu 
            500         


<210>  840
<211>  512
<212>  PRT
<213>  Homo Sapiens

<400>  840

Gln Ile Cys Pro Lys Arg Cys Val Cys Gln Ile Leu Ser Pro Asn Leu 
1               5                   10                  15      


Ala Thr Leu Cys Ala Lys Lys Gly Leu Leu Phe Val Pro Pro Asn Ile 
            20                  25                  30          


Asp Arg Arg Thr Val Glu Leu Arg Leu Ala Asp Asn Phe Val Thr Asn 
        35                  40                  45              


Ile Lys Arg Lys Asp Phe Ala Asn Met Thr Ser Leu Val Asp Leu Thr 
    50                  55                  60                  


Leu Ser Arg Asn Thr Ile Ser Phe Ile Thr Pro His Ala Phe Ala Asp 
65                  70                  75                  80  


Leu Arg Asn Leu Arg Ala Leu His Leu Asn Ser Asn Arg Leu Thr Lys 
                85                  90                  95      


Ile Thr Asn Asp Met Phe Ser Gly Leu Ser Asn Leu His His Leu Ile 
            100                 105                 110         


Leu Asn Asn Asn Gln Leu Thr Leu Ile Ser Ser Thr Ala Phe Asp Asp 
        115                 120                 125             


Val Phe Ala Leu Glu Glu Leu Asp Leu Ser Tyr Asn Asn Leu Glu Thr 
    130                 135                 140                 


Ile Pro Trp Asp Ala Val Glu Lys Met Val Ser Leu His Thr Leu Ser 
145                 150                 155                 160 


Leu Asp His Asn Met Ile Asp Asn Ile Pro Lys Gly Thr Phe Ser His 
                165                 170                 175     


Leu His Lys Met Thr Arg Leu Asp Val Thr Ser Asn Lys Leu Gln Lys 
            180                 185                 190         


Leu Pro Pro Asp Pro Leu Phe Gln Arg Ala Gln Val Leu Ala Thr Ser 
        195                 200                 205             


Gly Ile Ile Ser Pro Ser Thr Phe Ala Leu Ser Phe Gly Gly Asn Pro 
    210                 215                 220                 


Leu His Cys Asn Cys Glu Leu Leu Trp Leu Arg Arg Leu Ser Arg Glu 
225                 230                 235                 240 


Asp Asp Leu Glu Thr Cys Ala Ser Pro Pro Leu Leu Thr Gly Arg Tyr 
                245                 250                 255     


Phe Trp Ser Ile Pro Glu Glu Glu Phe Leu Cys Glu Pro Pro Leu Ile 
            260                 265                 270         


Thr Arg His Thr His Glu Met Arg Val Leu Glu Gly Gln Arg Ala Thr 
        275                 280                 285             


Leu Arg Cys Lys Ala Arg Gly Asp Pro Glu Pro Ala Ile His Trp Ile 
    290                 295                 300                 


Ser Pro Glu Gly Lys Leu Ile Ser Asn Ala Thr Arg Ser Leu Val Tyr 
305                 310                 315                 320 


Asp Asn Gly Thr Leu Asp Ile Leu Ile Thr Thr Val Lys Asp Thr Gly 
                325                 330                 335     


Ala Phe Thr Cys Ile Ala Ser Asn Pro Ala Gly Glu Ala Thr Gln Ile 
            340                 345                 350         


Val Asp Leu His Ile Ile Lys Leu Pro His Leu Leu Asn Ser Thr Asn 
        355                 360                 365             


His Ile His Glu Pro Asp Pro Gly Ser Ser Asp Ile Ser Thr Ser Thr 
    370                 375                 380                 


Lys Ser Gly Ser Asn Thr Ser Ser Ser Asn Gly Asp Thr Lys Leu Ser 
385                 390                 395                 400 


Gln Asp Lys Ile Val Val Ala Glu Ala Thr Ser Ser Thr Ala Leu Leu 
                405                 410                 415     


Lys Phe Asn Phe Gln Arg Asn Ile Pro Gly Ile Arg Met Phe Gln Ile 
            420                 425                 430         


Gln Tyr Asn Gly Thr Tyr Asp Asp Thr Leu Val Tyr Arg Met Ile Pro 
        435                 440                 445             


Pro Thr Ser Lys Thr Phe Leu Val Asn Asn Leu Ala Ala Gly Thr Met 
    450                 455                 460                 


Tyr Asp Leu Cys Val Leu Ala Ile Tyr Asp Asp Gly Ile Thr Ser Leu 
465                 470                 475                 480 


Thr Ala Thr Arg Val Val Gly Cys Ile Gln Phe Thr Thr Glu Gln Asp 
                485                 490                 495     


Tyr Val Arg Cys His Phe Met Gln Ser Gln Phe Leu Gly Gly Thr Met 
            500                 505                 510         


<210>  841
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  841

Val Thr Leu Ser Pro Lys Asp Cys Gln Val Phe Arg Ser Asp His Gly 
1               5                   10                  15      


Ser Ser Ile Ser Cys Gln Pro Pro Ala Glu Ile Pro Gly Tyr Leu Pro 
            20                  25                  30          


Ala Asp Thr Val His Leu Ala Val Glu Phe Phe Asn Leu Thr His Leu 
        35                  40                  45              


Pro Ala Asn Leu Leu Gln Gly Ala Ser Lys Leu Gln Glu Leu His Leu 
    50                  55                  60                  


Ser Ser Asn Gly Leu Glu Ser Leu Ser Pro Glu Phe Leu Arg Pro Val 
65                  70                  75                  80  


Pro Gln Leu Arg Val Leu Asp Leu Thr Arg Asn Ala Leu Thr Gly Leu 
                85                  90                  95      


Pro Ser Gly Leu Phe Gln Ala Ser Ala Thr Leu Asp Thr Leu Val Leu 
            100                 105                 110         


Lys Glu Asn Gln Leu Glu Val Leu Glu Val Ser Trp Leu His Gly Leu 
        115                 120                 125             


Lys Ala Leu Gly His Leu Asp Leu Ser Gly Asn Arg Leu Arg Lys Leu 
    130                 135                 140                 


Pro Pro Gly Leu Leu Ala Asn Phe Thr Leu Leu Arg Thr Leu Asp Leu 
145                 150                 155                 160 


Gly Glu Asn Gln Leu Glu Thr Leu Pro Pro Asp Leu Leu Arg Gly Pro 
                165                 170                 175     


Leu Gln Leu Glu Arg Leu His Leu Glu Gly Asn Lys Leu Gln Val Leu 
            180                 185                 190         


Gly Lys Asp Leu Leu Leu Pro Gln Pro Asp Leu Arg Tyr Leu Phe Leu 
        195                 200                 205             


Asn Gly Asn Lys Leu Ala Arg Val Ala Ala Gly Ala Phe Gln Gly Leu 
    210                 215                 220                 


Arg Gln Leu Asp Met Leu Asp Leu Ser Asn Asn Ser Leu Ala Ser Val 
225                 230                 235                 240 


Pro Glu Gly Leu Trp Ala Ser Leu Gly Gln Pro Asn Trp Asp Met Arg 
                245                 250                 255     


Asp Gly Phe Asp Ile Ser Gly Asn Pro Trp Ile Cys Asp Gln Asn Leu 
            260                 265                 270         


Ser Asp Leu Tyr Arg Trp Leu Gln Ala Gln Lys Asp Lys Met Phe Ser 
        275                 280                 285             


Gln Asn Asp Thr Arg Cys Ala Gly Pro Glu Ala Val Lys Gly Gln Thr 
    290                 295                 300                 


Leu Leu Ala Val Ala Lys Ser Gln 
305                 310         


<210>  842
<211>  737
<212>  PRT
<213>  Homo Sapiens

<400>  842

Ala Gly Pro Arg Ala Pro Cys Ala Ala Ala Cys Thr Cys Ala Gly Asp 
1               5                   10                  15      


Ser Leu Asp Cys Gly Gly Arg Gly Leu Ala Ala Leu Pro Gly Asp Leu 
            20                  25                  30          


Pro Ser Trp Thr Arg Ser Leu Asn Leu Ser Tyr Asn Lys Phe Ser Glu 
        35                  40                  45              


Ile Asp Pro Ala Gly Phe Glu Asp Leu Pro Asn Leu Gln Glu Val Tyr 
    50                  55                  60                  


Leu Asn Asn Asn Glu Leu Thr Ala Val Pro Ser Leu Gly Ala Ala Ser 
65                  70                  75                  80  


Ser His Val Val Ser Leu Phe Leu Gln His Asn Lys Ile Arg Ser Val 
                85                  90                  95      


Glu Gly Ser Gln Leu Lys Ala Tyr Leu Ser Leu Glu Val Leu Asp Leu 
            100                 105                 110         


Ser Leu Asn Asn Ile Thr Glu Val Arg Asn Thr Cys Phe Pro His Gly 
        115                 120                 125             


Pro Pro Ile Lys Glu Leu Asn Leu Ala Gly Asn Arg Ile Gly Thr Leu 
    130                 135                 140                 


Glu Leu Gly Ala Phe Asp Gly Leu Ser Arg Ser Leu Leu Thr Leu Arg 
145                 150                 155                 160 


Leu Ser Lys Asn Arg Ile Thr Gln Leu Pro Val Arg Ala Phe Lys Leu 
                165                 170                 175     


Pro Arg Leu Thr Gln Leu Asp Leu Asn Arg Asn Arg Ile Arg Leu Ile 
            180                 185                 190         


Glu Gly Leu Thr Phe Gln Gly Leu Asn Ser Leu Glu Val Leu Lys Leu 
        195                 200                 205             


Gln Arg Asn Asn Ile Ser Lys Leu Thr Asp Gly Ala Phe Trp Gly Leu 
    210                 215                 220                 


Ser Lys Met His Val Leu His Leu Glu Tyr Asn Ser Leu Val Glu Val 
225                 230                 235                 240 


Asn Ser Gly Ser Leu Tyr Gly Leu Thr Ala Leu His Gln Leu His Leu 
                245                 250                 255     


Ser Asn Asn Ser Ile Ala Arg Ile His Arg Lys Gly Trp Ser Phe Cys 
            260                 265                 270         


Gln Lys Leu His Glu Leu Val Leu Ser Phe Asn Asn Leu Thr Arg Leu 
        275                 280                 285             


Asp Glu Glu Ser Leu Ala Glu Leu Ser Ser Leu Ser Val Leu Arg Leu 
    290                 295                 300                 


Ser His Asn Ser Ile Ser His Ile Ala Glu Gly Ala Phe Lys Gly Leu 
305                 310                 315                 320 


Arg Ser Leu Arg Val Leu Asp Leu Asp His Asn Glu Ile Ser Gly Thr 
                325                 330                 335     


Ile Glu Asp Thr Ser Gly Ala Phe Ser Gly Leu Asp Ser Leu Ser Lys 
            340                 345                 350         


Leu Leu Leu Leu Glu Pro Ser Gln Ser Ala Gly Cys Ser Ser Pro Ser 
        355                 360                 365             


Gln Pro His Met Ser Ala Gly Gly Arg Thr Leu Phe Gly Asn Lys Ile 
    370                 375                 380                 


Lys Ser Val Ala Lys Arg Ala Phe Ser Gly Leu Glu Gly Leu Glu His 
385                 390                 395                 400 


Leu Asn Leu Gly Gly Asn Ala Ile Arg Ser Val Gln Phe Asp Ala Phe 
                405                 410                 415     


Val Lys Met Lys Asn Leu Lys Glu Leu His Ile Ser Ser Asp Ser Phe 
            420                 425                 430         


Leu Cys Asp Cys Gln Leu Lys Trp Leu Pro Pro Trp Leu Ile Gly Arg 
        435                 440                 445             


Met Leu Gln Ala Phe Val Thr Ala Thr Cys Ala His Pro Glu Ser Leu 
    450                 455                 460                 


Lys Gly Gln Ser Ile Phe Ser Val Pro Pro Glu Ser Phe Val Cys Asp 
465                 470                 475                 480 


Asp Phe Leu Lys Pro Gln Ile Ile Thr Gln Pro Glu Thr Thr Met Ala 
                485                 490                 495     


Met Val Gly Lys Asp Ile Arg Phe Thr Cys Ser Ala Ala Ser Ser Ser 
            500                 505                 510         


Ser Ser Pro Met Thr Phe Ala Trp Lys Lys Asp Asn Glu Val Leu Thr 
        515                 520                 525             


Asn Ala Asp Met Glu Asn Phe Val His Val His Ala Gln Asp Gly Glu 
    530                 535                 540                 


Val Met Glu Tyr Thr Thr Ile Leu His Leu Arg Gln Val Thr Phe Gly 
545                 550                 555                 560 


His Glu Gly Arg Tyr Gln Cys Val Ile Thr Asn His Phe Gly Ser Thr 
                565                 570                 575     


Tyr Ser His Lys Ala Arg Leu Thr Val Asn Val Leu Pro Ser Phe Thr 
            580                 585                 590         


Lys Thr Pro His Asp Ile Thr Ile Arg Thr Thr Thr Met Ala Arg Leu 
        595                 600                 605             


Glu Cys Ala Ala Thr Gly His Pro Asn Pro Gln Ile Ala Trp Gln Lys 
    610                 615                 620                 


Asp Gly Gly Thr Asp Phe Pro Ala Ala Gln Thr Pro Ser Leu Val Val 
625                 630                 635                 640 


Pro Leu Glu Asp Arg Val Val Ser Val Gly Glu Thr Val Ala Leu Gln 
                645                 650                 655     


Cys Lys Ala Thr Gly Asn Pro Pro Pro Arg Ile Thr Trp Phe Lys Gly 
            660                 665                 670         


Asp Arg Pro Leu Ser Leu Thr Glu Arg His His Leu Thr Pro Asp Asn 
        675                 680                 685             


Gln Leu Leu Val Val Gln Asn Val Val Ala Glu Asp Ala Gly Arg Tyr 
    690                 695                 700                 


Thr Cys Glu Met Ser Asn Thr Leu Gly Thr Glu Arg Ala His Ser Gln 
705                 710                 715                 720 


Leu Ser Val Leu Pro Ala Ala Gly Cys Arg Lys Asp Gly Thr Thr Val 
                725                 730                 735     


Gly 
    


<210>  843
<211>  767
<212>  PRT
<213>  Homo Sapiens

<400>  843

Gly Leu Cys Pro Ala Pro Cys Ser Cys Arg Ile Pro Leu Leu Asp Cys 
1               5                   10                  15      


Ser Arg Arg Lys Leu Pro Ala Pro Ser Trp Arg Ala Leu Ser Gly Leu 
            20                  25                  30          


Leu Pro Pro Asp Thr Ala Ile Leu Asp Phe Ser His Asn Arg Leu Ser 
        35                  40                  45              


Asn Trp Asn Ile Ser Leu Glu Ser Gln Thr Leu Gln Glu Val Lys Met 
    50                  55                  60                  


Asn Tyr Asn Glu Leu Thr Glu Ile Pro Tyr Phe Gly Glu Pro Thr Ser 
65                  70                  75                  80  


Asn Ile Thr Leu Leu Ser Leu Val His Asn Ile Ile Pro Glu Ile Asn 
                85                  90                  95      


Ala Gln Ala Leu Gln Phe Tyr Pro Ala Leu Glu Ser Leu Asp Leu Ser 
            100                 105                 110         


Ser Asn Ile Ile Ser Glu Ile Lys Thr Ser Ser Phe Pro Arg Met Gln 
        115                 120                 125             


Leu Lys Tyr Leu Asn Leu Ser Asn Asn Arg Ile Thr Thr Leu Glu Ala 
    130                 135                 140                 


Gly Cys Phe Asp Asn Leu Ser Ser Ser Leu Leu Val Val Lys Leu Asn 
145                 150                 155                 160 


Arg Asn Arg Met Ser Met Ile Pro Pro Lys Ile Phe Lys Leu Pro His 
                165                 170                 175     


Leu Gln Phe Leu Glu Leu Lys Arg Asn Arg Ile Lys Ile Val Glu Gly 
            180                 185                 190         


Leu Thr Phe Gln Gly Leu Asp Ser Leu Arg Ser Leu Lys Met Gln Arg 
        195                 200                 205             


Asn Gly Ile Ser Lys Leu Lys Asp Gly Ala Phe Phe Gly Leu Asn Asn 
    210                 215                 220                 


Met Glu Glu Leu Glu Leu Glu His Asn Asn Leu Thr Arg Val Asn Lys 
225                 230                 235                 240 


Gly Trp Leu Tyr Gly Leu Arg Met Leu Gln Gln Leu Tyr Val Ser Gln 
                245                 250                 255     


Asn Ala Ile Glu Arg Ile Ser Pro Asp Ala Trp Glu Phe Cys Gln Arg 
            260                 265                 270         


Leu Ser Glu Leu Asp Leu Ser Tyr Asn Gln Leu Thr Arg Leu Asp Glu 
        275                 280                 285             


Ser Ala Phe Val Gly Leu Ser Leu Leu Glu Arg Leu Asn Leu Gly Asp 
    290                 295                 300                 


Asn Arg Val Thr His Ile Ala Asp Gly Val Phe Arg Phe Leu Ser Asn 
305                 310                 315                 320 


Leu Gln Thr Leu Asp Leu Arg Asn Asn Glu Ile Ser Trp Ala Ile Glu 
                325                 330                 335     


Asp Ala Ser Glu Ala Phe Ala Gly Leu Thr Ser Leu Thr Lys Leu Ile 
            340                 345                 350         


Leu Gln Gly Asn Gln Ile Lys Ser Ile Thr Lys Lys Ala Phe Ile Gly 
        355                 360                 365             


Leu Glu Ser Leu Glu His Leu Asp Leu Asn Asn Asn Ala Ile Met Ser 
    370                 375                 380                 


Ile Gln Glu Asn Ala Phe Ser Gln Thr His Leu Lys Glu Leu Ile Leu 
385                 390                 395                 400 


Asn Thr Ser Ser Leu Leu Cys Asp Cys His Leu Lys Trp Leu Leu Gln 
                405                 410                 415     


Trp Leu Val Asp Asn Asn Phe Gln His Ser Val Asn Val Ser Cys Ala 
            420                 425                 430         


His Pro Glu Trp Leu Ala Gly Gln Ser Ile Leu Asn Val Asp Leu Lys 
        435                 440                 445             


Asp Phe Val Cys Asp Asp Phe Leu Lys Pro Gln Ile Arg Thr His Pro 
    450                 455                 460                 


Glu Thr Ile Ile Ala Leu Arg Gly Met Asn Val Thr Leu Thr Cys Thr 
465                 470                 475                 480 


Ala Val Ser Ser Ser Asp Ser Pro Met Ser Thr Val Trp Arg Lys Asp 
                485                 490                 495     


Ser Glu Ile Leu Tyr Asp Val Asp Thr Glu Asn Phe Val Arg Tyr Trp 
            500                 505                 510         


Gln Gln Ala Gly Glu Ala Leu Glu Tyr Thr Ser Ile Leu His Leu Phe 
        515                 520                 525             


Asn Val Asn Phe Thr Asp Glu Gly Lys Tyr Gln Cys Ile Val Thr Asn 
    530                 535                 540                 


His Phe Gly Ser Asn Tyr Ser Gln Lys Ala Lys Leu Thr Val Asn Glu 
545                 550                 555                 560 


Met Pro Ser Phe Leu Lys Thr Pro Met Asp Leu Thr Ile Arg Thr Gly 
                565                 570                 575     


Ala Met Ala Arg Leu Glu Cys Ala Ala Glu Gly His Pro Ala Pro Gln 
            580                 585                 590         


Ile Ser Trp Gln Lys Asp Gly Gly Thr Asp Phe Pro Ala Ala Arg Glu 
        595                 600                 605             


Arg Arg Met His Val Met Pro Glu Asp Asp Val Phe Phe Ile Ala Asn 
    610                 615                 620                 


Val Lys Ile Glu Asp Met Gly Ile Tyr Ser Cys Met Ala Gln Asn Thr 
625                 630                 635                 640 


Ala Gly Gly Leu Ser Ala Asn Ala Ser Leu Thr Val Leu Glu Thr Pro 
                645                 650                 655     


Ser Phe Ile Arg Pro Leu Glu Asp Lys Thr Val Thr Arg Gly Glu Thr 
            660                 665                 670         


Ala Val Leu Gln Cys Ile Ala Gly Gly Ser Pro Ala Pro Arg Leu Asn 
        675                 680                 685             


Trp Thr Lys Asp Asp Gly Pro Leu Leu Val Thr Glu Arg His Phe Phe 
    690                 695                 700                 


Ala Ala Ala Asn Gln Leu Leu Ile Ile Val Asp Ala Gly Leu Glu Asp 
705                 710                 715                 720 


Ala Gly Lys Tyr Thr Cys Ile Met Ser Asn Thr Leu Gly Thr Glu Arg 
                725                 730                 735     


Gly His Ile Tyr Leu Asn Val Ile Ser Ser Pro Asn Cys Asp Ser Ser 
            740                 745                 750         


Gln Ser Ser Ile Gly His Glu Asp Asp Gly Trp Thr Thr Val Gly 
        755                 760                 765         


<210>  844
<211>  785
<212>  PRT
<213>  Homo Sapiens

<400>  844

Gly Arg Ser Asp Ser Gly Gly Arg Gly Glu Leu Gly Gln Pro Ser Gly 
1               5                   10                  15      


Val Ala Ala Glu Arg Pro Cys Pro Thr Thr Cys Arg Cys Leu Gly Asp 
            20                  25                  30          


Leu Leu Asp Cys Ser Arg Lys Arg Leu Ala Arg Leu Pro Glu Pro Leu 
        35                  40                  45              


Pro Ser Trp Val Ala Arg Leu Asp Leu Ser His Asn Arg Leu Ser Phe 
    50                  55                  60                  


Ile Lys Ala Ser Ser Met Ser His Leu Gln Ser Leu Arg Glu Val Lys 
65                  70                  75                  80  


Leu Asn Asn Asn Glu Leu Glu Thr Ile Pro Asn Leu Gly Pro Val Ser 
                85                  90                  95      


Ala Asn Ile Thr Leu Leu Ser Leu Ala Gly Asn Arg Ile Val Glu Ile 
            100                 105                 110         


Leu Pro Glu His Leu Lys Glu Phe Gln Ser Leu Glu Thr Leu Asp Leu 
        115                 120                 125             


Ser Ser Asn Asn Ile Ser Glu Leu Gln Thr Ala Phe Pro Ala Leu Gln 
    130                 135                 140                 


Leu Lys Tyr Leu Tyr Leu Asn Ser Asn Arg Val Thr Ser Met Glu Pro 
145                 150                 155                 160 


Gly Tyr Phe Asp Asn Leu Ala Asn Thr Leu Leu Val Leu Lys Leu Asn 
                165                 170                 175     


Arg Asn Arg Ile Ser Ala Ile Pro Pro Lys Met Phe Lys Leu Pro Gln 
            180                 185                 190         


Leu Gln His Leu Glu Leu Asn Arg Asn Lys Ile Lys Asn Val Asp Gly 
        195                 200                 205             


Leu Thr Phe Gln Gly Leu Gly Ala Leu Lys Ser Leu Lys Met Gln Arg 
    210                 215                 220                 


Asn Gly Val Thr Lys Leu Met Asp Gly Ala Phe Trp Gly Leu Ser Asn 
225                 230                 235                 240 


Met Glu Ile Leu Gln Leu Asp His Asn Asn Leu Thr Glu Ile Thr Lys 
                245                 250                 255     


Gly Trp Leu Tyr Gly Leu Leu Met Leu Gln Glu Leu His Leu Ser Gln 
            260                 265                 270         


Asn Ala Ile Asn Arg Ile Ser Pro Asp Ala Trp Glu Phe Cys Gln Lys 
        275                 280                 285             


Leu Ser Glu Leu Asp Leu Thr Phe Asn His Leu Ser Arg Leu Asp Asp 
    290                 295                 300                 


Ser Ser Phe Leu Gly Leu Ser Leu Leu Asn Thr Leu His Ile Gly Asn 
305                 310                 315                 320 


Asn Arg Val Ser Tyr Ile Ala Asp Cys Ala Phe Arg Gly Leu Ser Ser 
                325                 330                 335     


Leu Lys Thr Leu Asp Leu Lys Asn Asn Glu Ile Ser Trp Thr Ile Glu 
            340                 345                 350         


Asp Met Asn Gly Ala Phe Ser Gly Leu Asp Lys Leu Arg Arg Leu Ile 
        355                 360                 365             


Leu Gln Gly Asn Arg Ile Arg Ser Ile Thr Lys Lys Ala Phe Thr Gly 
    370                 375                 380                 


Leu Asp Ala Leu Glu His Leu Asp Leu Ser Asp Asn Ala Ile Met Ser 
385                 390                 395                 400 


Leu Gln Gly Asn Ala Phe Ser Gln Met Lys Lys Leu Gln Gln Leu His 
                405                 410                 415     


Leu Asn Thr Ser Ser Leu Leu Cys Asp Cys Gln Leu Lys Trp Leu Pro 
            420                 425                 430         


Gln Trp Val Ala Glu Asn Asn Phe Gln Ser Phe Val Asn Ala Ser Cys 
        435                 440                 445             


Ala His Pro Gln Leu Leu Lys Gly Arg Ser Ile Phe Ala Val Ser Pro 
    450                 455                 460                 


Asp Gly Phe Val Cys Asp Asp Phe Pro Lys Pro Gln Ile Thr Val Gln 
465                 470                 475                 480 


Pro Glu Thr Gln Ser Ala Ile Lys Gly Ser Asn Leu Ser Phe Ile Cys 
                485                 490                 495     


Ser Ala Ala Ser Ser Ser Asp Ser Pro Met Thr Phe Ala Trp Lys Lys 
            500                 505                 510         


Asp Asn Glu Leu Leu His Asp Ala Glu Met Glu Asn Tyr Ala His Leu 
        515                 520                 525             


Arg Ala Gln Gly Gly Glu Val Met Glu Tyr Thr Thr Ile Leu Arg Leu 
    530                 535                 540                 


Arg Glu Val Glu Phe Ala Ser Glu Gly Lys Tyr Gln Cys Val Ile Ser 
545                 550                 555                 560 


Asn His Phe Gly Ser Ser Tyr Ser Val Lys Ala Lys Leu Thr Val Asn 
                565                 570                 575     


Met Leu Pro Ser Phe Thr Lys Thr Pro Met Asp Leu Thr Ile Arg Ala 
            580                 585                 590         


Gly Ala Met Ala Arg Leu Glu Cys Ala Ala Val Gly His Pro Ala Pro 
        595                 600                 605             


Gln Ile Ala Trp Gln Lys Asp Gly Gly Thr Asp Phe Pro Ala Ala Arg 
    610                 615                 620                 


Glu Arg Arg Met His Val Met Pro Glu Asp Asp Val Phe Phe Ile Val 
625                 630                 635                 640 


Asp Val Lys Ile Glu Asp Ile Gly Val Tyr Ser Cys Thr Ala Gln Asn 
                645                 650                 655     


Ser Ala Gly Ser Ile Ser Ala Asn Ala Thr Leu Thr Val Leu Glu Thr 
            660                 665                 670         


Pro Ser Phe Leu Arg Pro Leu Leu Asp Arg Thr Val Thr Lys Gly Glu 
        675                 680                 685             


Thr Ala Val Leu Gln Cys Ile Ala Gly Gly Ser Pro Pro Pro Lys Leu 
    690                 695                 700                 


Asn Trp Thr Lys Asp Asp Ser Pro Leu Val Val Thr Glu Arg His Phe 
705                 710                 715                 720 


Phe Ala Ala Gly Asn Gln Leu Leu Ile Ile Val Asp Ser Asp Val Ser 
                725                 730                 735     


Asp Ala Gly Lys Tyr Thr Cys Glu Met Ser Asn Thr Leu Gly Thr Glu 
            740                 745                 750         


Arg Gly Asn Val Arg Leu Ser Val Ile Pro Thr Pro Thr Cys Asp Ser 
        755                 760                 765             


Pro Gln Met Thr Ala Pro Ser Leu Asp Asp Asp Gly Trp Ala Thr Val 
    770                 775                 780                 


Gly 
785 


<210>  845
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  845

Ala Gln Pro Phe Cys Leu Pro Gly Cys Thr Cys Ser Glu Glu Ser Phe 
1               5                   10                  15      


Gly Arg Thr Leu Gln Cys Thr Ser Val Ser Leu Gly Lys Ile Pro Gly 
            20                  25                  30          


Asn Leu Ser Glu Glu Phe Lys Gln Val Arg Ile Glu Asn Ser Pro Leu 
        35                  40                  45              


Phe Glu Met Pro Gln Gly Ser Phe Ile Asn Met Ser Thr Leu Glu Tyr 
    50                  55                  60                  


Leu Trp Leu Asn Phe Asn Asn Ile Ser Val Ile His Leu Gly Ala Leu 
65                  70                  75                  80  


Glu His Leu Pro Glu Leu Arg Glu Leu Arg Leu Glu Gly Asn Lys Leu 
                85                  90                  95      


Cys Ser Val Pro Trp Thr Ala Phe Arg Ala Thr Pro Leu Leu Arg Val 
            100                 105                 110         


Leu Asp Leu Lys Arg Asn Lys Ile Asp Ala Leu Pro Glu Leu Ala Leu 
        115                 120                 125             


Gln Phe Leu Val Ser Leu Thr Tyr Leu Asp Leu Ser Ser Asn Arg Leu 
    130                 135                 140                 


Thr Val Val Ser Lys Ser Val Phe Leu Asn Trp Pro Ala Tyr Gln Lys 
145                 150                 155                 160 


Cys Arg Gln Pro Asp Cys Gly Ala Glu Ile Leu Ser Ser Leu Val Val 
                165                 170                 175     


Ala Leu His Asp Asn Pro Trp Val Cys Asp Cys Arg Leu Arg Gly Leu 
            180                 185                 190         


Val Gln Phe Val Lys Ser Ile Thr Leu Pro Val Ile Leu Val Asn Ser 
        195                 200                 205             


Tyr Leu Ile Cys Gln Gly Pro Leu Ser Lys Ala Gly Gln Leu Phe His 
    210                 215                 220                 


Glu Thr Glu Leu Ser Ala Cys Met Lys Pro Gln Ile Ser Thr Pro Ser 
225                 230                 235                 240 


Ala Asn Ile Thr Ile Arg Ala Gly Gln Asn Val Thr Leu Arg Cys Leu 
                245                 250                 255     


Ala Gln Ala Ser Pro Ser Pro Ser Ile Ala Trp Thr Tyr Pro Leu Ser 
            260                 265                 270         


Met Trp Arg Glu Phe Asp Gly Leu Leu Gly Gly Lys His Leu Thr Pro 
        275                 280                 285             


Val Leu Thr Ser Ser Thr Gly Glu Asp Thr Ala Leu Ser Glu Leu Ala 
    290                 295                 300                 


Ile Pro Ala Ala His Leu Val Asp Ser Gly Asn Tyr Thr Cys Met Ala 
305                 310                 315                 320 


Ser Asn Ser Ile Gly Lys Ser Asn Leu Val Ile Ser Leu His Val Gln 
                325                 330                 335     


Pro Ala Gln Ala Leu His Ala Pro Asp Ser Leu Ser Ile Pro Ser Glu 
            340                 345                 350         


Gly Asn Ala Tyr Ile Asp Leu Arg Val Val Lys Gln Thr Val His Gly 
        355                 360                 365             


Ile Leu Leu Glu Trp Leu Ala Val Ala Asp Thr Ser Lys Glu Glu Trp 
    370                 375                 380                 


Phe Thr Leu Tyr Ile Ala Ser Asp Glu Ala Phe Arg Lys Glu Val Val 
385                 390                 395                 400 


His Ile Gly Pro Gly Ile Asn Thr Tyr Ala Val Asp Asp Leu Leu Pro 
                405                 410                 415     


Gly Thr Lys Tyr Glu Ala Cys Leu Ser Leu Glu Gly Gln Pro Pro His 
            420                 425                 430         


Gln Gly Gln Cys Val Ala Phe Val Thr Gly Arg Asp Ala Gly Gly Leu 
        435                 440                 445             


Glu Ala Arg Glu His Leu Leu His 
    450                 455     


<210>  846
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  846

Pro Ser Val Met Thr Ser Ala Thr Lys Ile Met Ser Ala Leu Gly Ser 
1               5                   10                  15      


Asn Val Leu Leu Arg Cys Asp Ala Thr Gly Phe Pro Thr Pro Gln Ile 
            20                  25                  30          


Thr Trp Thr Arg Ser Asp Ser Ser Pro Val Asn Tyr Thr Val Ile Gln 
        35                  40                  45              


Glu Ser Pro Glu Glu Gly Val Arg Trp Ser Ile Met Ser Leu Thr Gly 
    50                  55                  60                  


Ile Ser Ser Lys Asp Ala Gly Asp Tyr Lys Cys Lys Ala Lys Asn Leu 
65                  70                  75                  80  


Ala Gly Met Ser Glu Ala Val Val Thr Val Thr Val Leu Gly Ile Thr 
                85                  90                  95      


Thr Thr Pro Ile Pro Pro Asp Thr Ser Glu Arg Thr Gly Asp His Pro 
            100                 105                 110         


Glu Trp Asp Val Gln Pro Gly Ser Gly Arg Ser Thr Ser Val Ser Ser 
        115                 120                 125             


Ala Ser Ser Tyr Leu Trp Ser Ser Ser Phe Ser Pro Thr Ser Ser Phe 
    130                 135                 140                 


Ser Ala Ser Thr Leu Ser Pro Pro Ser Thr Ala Ser Phe Ser Leu Ser 
145                 150                 155                 160 


Pro Phe Ser Ser Ser Thr Val Ser Ser Thr Thr Thr Leu Ser Thr Ser 
                165                 170                 175     


Ile Ser Ala Ser Thr Thr Met Ala Asn Lys Arg Ser Phe Gln Leu His 
            180                 185                 190         


Gln Gly Gly Lys Arg Asn Leu Lys Val Ala Lys Asn Gly Ser Lys Leu 
        195                 200                 205             


Pro Pro Ala Ser Thr Ser Lys Lys Glu Glu Leu Ala Leu Leu Asp Gln 
    210                 215                 220                 


Thr Met Leu Thr Glu Thr Asn Ala Thr Ile Glu Asn Leu Arg Val Val 
225                 230                 235                 240 


Ser Glu Thr Lys Glu Ser Val Thr Leu Met Trp Asn Met Ile Asn Thr 
                245                 250                 255     


Thr His Asn Ser Ala Val Thr Val Leu Tyr Ser Lys Tyr Gly Gly Lys 
            260                 265                 270         


Asp Leu Leu Leu Leu Asn Ala Asp Ser Ser Lys Asn Gln Val Thr Ile 
        275                 280                 285             


Asp Gly Leu Glu Pro Gly Gly Gln Tyr Met Ala Cys Val Cys Pro Lys 
    290                 295                 300                 


Gly Val Pro Pro Gln Lys Asp Gln Cys Ile Thr Phe Ser Thr Glu Arg 
305                 310                 315                 320 


Val Glu Gly Asp Asp Ser Gln Trp Ser 
                325                 


<210>  847
<211>  413
<212>  PRT
<213>  Homo Sapiens

<400>  847

Ala Leu Pro Pro Ala Ala Pro Leu Ser Glu Leu His Ala Gln Leu Ser 
1               5                   10                  15      


Gly Val Glu Gln Leu Leu Glu Glu Phe Arg Arg Gln Leu Gln Gln Glu 
            20                  25                  30          


Arg Pro Gln Glu Glu Leu Glu Leu Glu Leu Arg Ala Gly Gly Gly Pro 
        35                  40                  45              


Gln Glu Asp Cys Pro Gly Arg Gly Ser Gly Gly Tyr Ser Ala Met Pro 
    50                  55                  60                  


Asp Ala Ile Ile Arg Thr Lys Asp Ser Leu Ala Ala Gly Ala Ser Phe 
65                  70                  75                  80  


Leu Arg Ala Pro Ala Ala Val Arg Gly Trp Arg Gln Cys Val Ala Ala 
                85                  90                  95      


Cys Cys Ser Glu Pro Arg Cys Ser Val Ala Val Val Glu Leu Pro Arg 
            100                 105                 110         


Arg Pro Ala Pro Pro Ala Ala Val Leu Gly Cys Tyr Leu Phe Asn Cys 
        115                 120                 125             


Thr Ala Arg Gly Arg Asn Val Cys Lys Phe Ala Leu His Ser Gly Tyr 
    130                 135                 140                 


Ser Ser Tyr Ser Leu Ser Arg Ala Pro Asp Gly Ala Ala Leu Ala Thr 
145                 150                 155                 160 


Ala Arg Ala Ser Pro Arg Gln Glu Lys Asp Ala Pro Pro Leu Ser Lys 
                165                 170                 175     


Ala Gly Gln Asp Val Val Leu His Leu Pro Thr Asp Gly Val Val Leu 
            180                 185                 190         


Asp Gly Arg Glu Ser Thr Asp Asp His Ala Ile Val Gln Tyr Glu Trp 
        195                 200                 205             


Ala Leu Leu Gln Gly Asp Pro Ser Val Asp Met Lys Val Pro Gln Ser 
    210                 215                 220                 


Gly Thr Leu Lys Leu Ser His Leu Gln Glu Gly Thr Tyr Thr Phe Gln 
225                 230                 235                 240 


Leu Thr Val Thr Asp Thr Ala Gly Gln Arg Ser Ser Asp Asn Val Ser 
                245                 250                 255     


Val Thr Val Leu Arg Ala Ala Tyr Ser Thr Gly Gly Cys Leu His Thr 
            260                 265                 270         


Cys Ser Arg Tyr His Phe Phe Cys Asp Asp Gly Cys Cys Ile Asp Ile 
        275                 280                 285             


Thr Leu Ala Cys Asp Gly Val Gln Gln Cys Pro Asp Gly Ser Asp Glu 
    290                 295                 300                 


Asp Phe Cys Gln Asn Leu Gly Leu Asp His Lys Met Val Thr His Thr 
305                 310                 315                 320 


Ala Ala Ser Pro Ala Leu Pro Arg Thr Thr Gly Pro Ser Glu Asp Ala 
                325                 330                 335     


Gly Gly Asp Ser Leu Val Glu Lys Ser Gln Lys Ala Thr Ala Pro Asn 
            340                 345                 350         


Lys Pro Pro Ala Leu Ser Asn Thr Glu Lys Arg Asn His Ser Ala Phe 
        355                 360                 365             


Trp Gly Pro Glu Ser Gln Ile Ile Pro Val Met Pro Asp Ser Ser Ser 
    370                 375                 380                 


Ser Gly Lys Asn Arg Lys Glu Glu Ser Tyr Ile Phe Glu Ser Lys Gly 
385                 390                 395                 400 


Asp Gly Gly Gly Gly Glu His Pro Ala Pro Glu Thr Gly 
                405                 410             


<210>  848
<211>  1705
<212>  PRT
<213>  Homo Sapiens

<400>  848

Ser Ser Pro Glu Cys Ala Cys Gly Arg Ser His Phe Thr Cys Ala Val 
1               5                   10                  15      


Ser Ala Leu Gly Glu Cys Thr Cys Ile Pro Ala Gln Trp Gln Cys Asp 
            20                  25                  30          


Gly Asp Asn Asp Cys Gly Asp His Ser Asp Glu Asp Gly Cys Ile Leu 
        35                  40                  45              


Pro Thr Cys Ser Pro Leu Asp Phe His Cys Asp Asn Gly Lys Cys Ile 
    50                  55                  60                  


Arg Arg Ser Trp Val Cys Asp Gly Asp Asn Asp Cys Glu Asp Asp Ser 
65                  70                  75                  80  


Asp Glu Gln Asp Cys Pro Pro Arg Glu Cys Glu Glu Asp Glu Phe Pro 
                85                  90                  95      


Cys Gln Asn Gly Tyr Cys Ile Arg Ser Leu Trp His Cys Asp Gly Asp 
            100                 105                 110         


Asn Asp Cys Gly Asp Asn Ser Asp Glu Gln Cys Asp Met Arg Lys Cys 
        115                 120                 125             


Ser Asp Lys Glu Phe Arg Cys Ser Asp Gly Ser Cys Ile Ala Glu His 
    130                 135                 140                 


Trp Tyr Cys Asp Gly Asp Thr Asp Cys Lys Asp Gly Ser Asp Glu Glu 
145                 150                 155                 160 


Asn Cys Pro Ser Ala Val Pro Ala Pro Pro Cys Asn Leu Glu Glu Phe 
                165                 170                 175     


Gln Cys Ala Tyr Gly Arg Cys Ile Leu Asp Ile Tyr His Cys Asp Gly 
            180                 185                 190         


Asp Asp Asp Cys Gly Asp Trp Ser Asp Glu Ser Asp Cys Ser Ser His 
        195                 200                 205             


Gln Pro Cys Arg Ser Gly Glu Phe Met Cys Asp Ser Gly Leu Cys Ile 
    210                 215                 220                 


Asn Ala Gly Trp Arg Cys Asp Gly Asp Ala Asp Cys Asp Asp Gln Ser 
225                 230                 235                 240 


Asp Glu Arg Asn Cys Thr Thr Ser Met Cys Thr Ala Glu Gln Phe Arg 
                245                 250                 255     


Cys His Ser Gly Arg Cys Val Arg Leu Ser Trp Arg Cys Asp Gly Glu 
            260                 265                 270         


Asp Asp Cys Ala Asp Asn Ser Asp Glu Glu Asn Cys Glu Asn Thr Gly 
        275                 280                 285             


Ser Pro Gln Cys Ala Leu Asp Gln Phe Leu Cys Trp Asn Gly Arg Cys 
    290                 295                 300                 


Ile Gly Gln Arg Lys Leu Cys Asn Gly Val Asn Asp Cys Gly Asp Asn 
305                 310                 315                 320 


Ser Asp Glu Ser Pro Gln Gln Asn Cys Arg Pro Arg Thr Gly Glu Glu 
                325                 330                 335     


Asn Cys Asn Val Asn Asn Gly Gly Cys Ala Gln Lys Cys Gln Met Val 
            340                 345                 350         


Arg Gly Ala Val Gln Cys Thr Cys His Thr Gly Tyr Arg Leu Thr Glu 
        355                 360                 365             


Asp Gly His Thr Cys Gln Asp Val Asn Glu Cys Ala Glu Glu Gly Tyr 
    370                 375                 380                 


Cys Ser Gln Gly Cys Thr Asn Ser Glu Gly Ala Phe Gln Cys Trp Cys 
385                 390                 395                 400 


Glu Thr Gly Tyr Glu Leu Arg Pro Asp Arg Arg Ser Cys Lys Ala Leu 
                405                 410                 415     


Gly Pro Glu Pro Val Leu Leu Phe Ala Asn Arg Ile Asp Ile Arg Gln 
            420                 425                 430         


Val Leu Pro His Arg Ser Glu Tyr Thr Leu Leu Leu Asn Asn Leu Glu 
        435                 440                 445             


Asn Ala Ile Ala Leu Asp Phe His His Arg Arg Glu Leu Val Phe Trp 
    450                 455                 460                 


Ser Asp Val Thr Leu Asp Arg Ile Leu Arg Ala Asn Leu Asn Gly Ser 
465                 470                 475                 480 


Asn Val Glu Glu Val Val Ser Thr Gly Leu Glu Ser Pro Gly Gly Leu 
                485                 490                 495     


Ala Val Asp Trp Val His Asp Lys Leu Tyr Trp Thr Asp Ser Gly Thr 
            500                 505                 510         


Ser Arg Ile Glu Val Ala Asn Leu Asp Gly Ala His Arg Lys Val Leu 
        515                 520                 525             


Leu Trp Gln Asn Leu Glu Lys Pro Arg Ala Ile Ala Leu His Pro Met 
    530                 535                 540                 


Glu Gly Thr Ile Tyr Trp Thr Asp Trp Gly Asn Thr Pro Arg Ile Glu 
545                 550                 555                 560 


Ala Ser Ser Met Asp Gly Ser Gly Arg Arg Ile Ile Ala Asp Thr His 
                565                 570                 575     


Leu Phe Trp Pro Asn Gly Leu Thr Ile Asp Tyr Ala Gly Arg Arg Met 
            580                 585                 590         


Tyr Trp Val Asp Ala Lys His His Val Ile Glu Arg Ala Asn Leu Asp 
        595                 600                 605             


Gly Ser His Arg Lys Ala Val Ile Ser Gln Gly Leu Pro His Pro Phe 
    610                 615                 620                 


Ala Ile Thr Val Phe Glu Asp Ser Leu Tyr Trp Thr Asp Trp His Thr 
625                 630                 635                 640 


Lys Ser Ile Asn Ser Ala Asn Lys Phe Thr Gly Lys Asn Gln Glu Ile 
                645                 650                 655     


Ile Arg Asn Lys Leu His Phe Pro Met Asp Ile His Thr Leu His Pro 
            660                 665                 670         


Gln Arg Gln Pro Ala Gly Lys Asn Arg Cys Gly Asp Asn Asn Gly Gly 
        675                 680                 685             


Cys Thr His Leu Cys Leu Pro Ser Gly Gln Asn Tyr Thr Cys Ala Cys 
    690                 695                 700                 


Pro Thr Gly Phe Arg Lys Ile Ser Ser His Ala Cys Ala Gln Ser Leu 
705                 710                 715                 720 


Asp Lys Phe Leu Leu Phe Ala Arg Arg Met Asp Ile Arg Arg Ile Ser 
                725                 730                 735     


Phe Asp Thr Glu Asp Leu Ser Asp Asp Val Ile Pro Leu Ala Asp Val 
            740                 745                 750         


Arg Ser Ala Val Ala Leu Asp Trp Asp Ser Arg Asp Asp His Val Tyr 
        755                 760                 765             


Trp Thr Asp Val Ser Thr Asp Thr Ile Ser Arg Ala Lys Trp Asp Gly 
    770                 775                 780                 


Thr Gly Gln Glu Val Val Val Asp Thr Ser Leu Glu Ser Pro Ala Gly 
785                 790                 795                 800 


Leu Ala Ile Asp Trp Val Thr Asn Lys Leu Tyr Trp Thr Asp Ala Gly 
                805                 810                 815     


Thr Asp Arg Ile Glu Val Ala Asn Thr Asp Gly Ser Met Arg Thr Val 
            820                 825                 830         


Leu Ile Trp Glu Asn Leu Asp Arg Pro Arg Asp Ile Val Val Glu Pro 
        835                 840                 845             


Met Gly Gly Tyr Met Tyr Trp Thr Asp Trp Gly Ala Ser Pro Lys Ile 
    850                 855                 860                 


Glu Arg Ala Gly Met Asp Ala Ser Gly Arg Gln Val Ile Ile Ser Ser 
865                 870                 875                 880 


Asn Leu Thr Trp Pro Asn Gly Leu Ala Ile Asp Tyr Gly Ser Gln Arg 
                885                 890                 895     


Leu Tyr Trp Ala Asp Ala Gly Met Lys Thr Ile Glu Phe Ala Gly Leu 
            900                 905                 910         


Asp Gly Ser Lys Arg Lys Val Leu Ile Gly Ser Gln Leu Pro His Pro 
        915                 920                 925             


Phe Gly Leu Thr Leu Tyr Gly Glu Arg Ile Tyr Trp Thr Asp Trp Gln 
    930                 935                 940                 


Thr Lys Ser Ile Gln Ser Ala Asp Arg Leu Thr Gly Leu Asp Arg Glu 
945                 950                 955                 960 


Thr Leu Gln Glu Asn Leu Glu Asn Leu Met Asp Ile His Val Phe His 
                965                 970                 975     


Arg Arg Arg Pro Pro Val Ser Thr Pro Cys Ala Met Glu Asn Gly Gly 
            980                 985                 990         


Cys Ser His Leu Cys Leu Arg Ser  Pro Asn Pro Ser Gly  Phe Ser Cys 
        995                 1000                 1005             


Thr Cys  Pro Thr Gly Ile Asn  Leu Leu Ser Asp Gly  Lys Thr Cys 
    1010                 1015                 1020             


Ser Pro  Gly Met Asn Ser Phe  Leu Ile Phe Ala Arg  Arg Ile Asp 
    1025                 1030                 1035             


Ile Arg  Met Val Ser Leu Asp  Ile Pro Tyr Phe Ala  Asp Val Val 
    1040                 1045                 1050             


Val Pro  Ile Asn Ile Thr Met  Lys Asn Thr Ile Ala  Val Gly Val 
    1055                 1060                 1065             


Asp Pro  Gln Glu Gly Lys Val  Tyr Trp Ser Asp Ser  Thr Leu His 
    1070                 1075                 1080             


Arg Ile  Ser Arg Ala Asn Leu  Asp Gly Ser Gln His  Glu Asp Ile 
    1085                 1090                 1095             


Ile Thr  Thr Gly Leu Gln Thr  Thr Asp Gly Leu Ala  Val Asp Ala 
    1100                 1105                 1110             


Ile Gly  Arg Lys Val Tyr Trp  Thr Asp Thr Gly Thr  Asn Arg Ile 
    1115                 1120                 1125             


Glu Val  Gly Asn Leu Asp Gly  Ser Met Arg Lys Val  Leu Val Trp 
    1130                 1135                 1140             


Gln Asn  Leu Asp Ser Pro Arg  Ala Ile Val Leu Tyr  His Glu Met 
    1145                 1150                 1155             


Gly Phe  Met Tyr Trp Thr Asp  Trp Gly Glu Asn Ala  Lys Leu Glu 
    1160                 1165                 1170             


Arg Ser  Gly Met Asp Gly Ser  Asp Arg Ala Val Leu  Ile Asn Asn 
    1175                 1180                 1185             


Asn Leu  Gly Trp Pro Asn Gly  Leu Thr Val Asp Lys  Ala Ser Ser 
    1190                 1195                 1200             


Gln Leu  Leu Trp Ala Asp Ala  His Thr Glu Arg Ile  Glu Ala Ala 
    1205                 1210                 1215             


Asp Leu  Asn Gly Ala Asn Arg  His Thr Leu Val Ser  Pro Val Gln 
    1220                 1225                 1230             


His Pro  Tyr Gly Leu Thr Leu  Leu Asp Ser Tyr Ile  Tyr Trp Thr 
    1235                 1240                 1245             


Asp Trp  Gln Thr Arg Ser Ile  His Arg Ala Asp Lys  Gly Thr Gly 
    1250                 1255                 1260             


Ser Asn  Val Ile Leu Val Arg  Ser Asn Leu Pro Gly  Leu Met Asp 
    1265                 1270                 1275             


Met Gln  Ala Val Asp Arg Ala  Gln Pro Leu Gly Phe  Asn Lys Cys 
    1280                 1285                 1290             


Gly Ser  Arg Asn Gly Gly Cys  Ser His Leu Cys Leu  Pro Arg Pro 
    1295                 1300                 1305             


Ser Gly  Phe Ser Cys Ala Cys  Pro Thr Gly Ile Gln  Leu Lys Gly 
    1310                 1315                 1320             


Asp Gly  Lys Thr Cys Asp Pro  Ser Pro Glu Thr Tyr  Leu Leu Phe 
    1325                 1330                 1335             


Ser Ser  Arg Gly Ser Ile Arg  Arg Ile Ser Leu Asp  Thr Ser Asp 
    1340                 1345                 1350             


His Thr  Asp Val His Val Pro  Val Pro Glu Leu Asn  Asn Val Ile 
    1355                 1360                 1365             


Ser Leu  Asp Tyr Asp Ser Val  Asp Gly Lys Val Tyr  Tyr Thr Asp 
    1370                 1375                 1380             


Val Phe  Leu Asp Val Ile Arg  Arg Ala Asp Leu Asn  Gly Ser Asn 
    1385                 1390                 1395             


Met Glu  Thr Val Ile Gly Arg  Gly Leu Lys Thr Thr  Asp Gly Leu 
    1400                 1405                 1410             


Ala Val  Asp Trp Val Ala Arg  Asn Leu Tyr Trp Thr  Asp Thr Gly 
    1415                 1420                 1425             


Arg Asn  Thr Ile Glu Ala Ser  Arg Leu Asp Gly Ser  Cys Arg Lys 
    1430                 1435                 1440             


Val Leu  Ile Asn Asn Ser Leu  Asp Glu Pro Arg Ala  Ile Ala Val 
    1445                 1450                 1455             


Phe Pro  Arg Lys Gly Tyr Leu  Phe Trp Thr Asp Trp  Gly His Ile 
    1460                 1465                 1470             


Ala Lys  Ile Glu Arg Ala Asn  Leu Asp Gly Ser Glu  Arg Lys Val 
    1475                 1480                 1485             


Leu Ile  Asn Thr Asp Leu Gly  Trp Pro Asn Gly Leu  Thr Leu Asp 
    1490                 1495                 1500             


Tyr Asp  Thr Arg Arg Ile Tyr  Trp Val Asp Ala His  Leu Asp Arg 
    1505                 1510                 1515             


Ile Glu  Ser Ala Asp Leu Asn  Gly Lys Leu Arg Gln  Val Leu Val 
    1520                 1525                 1530             


Gly His  Val Ser His Pro Phe  Ala Leu Thr Gln Gln  Asp Arg Trp 
    1535                 1540                 1545             


Ile Tyr  Trp Thr Asp Trp Gln  Thr Lys Ser Ile Gln  Arg Val Asp 
    1550                 1555                 1560             


Lys Tyr  Ser Gly Arg Asn Lys  Glu Thr Val Leu Ala  Asn Val Glu 
    1565                 1570                 1575             


Gly Leu  Met Asp Ile Ile Val  Val Ser Pro Gln Arg  Gln Thr Gly 
    1580                 1585                 1590             


Thr Asn  Ala Cys Gly Val Asn  Asn Gly Gly Cys Thr  His Leu Cys 
    1595                 1600                 1605             


Phe Ala  Arg Ala Ser Asp Phe  Val Cys Ala Cys Pro  Asp Glu Pro 
    1610                 1615                 1620             


Asp Ser  Gln Pro Cys Ser Leu  Val Pro Gly Leu Val  Pro Pro Ala 
    1625                 1630                 1635             


Pro Arg  Ala Thr Gly Met Ser  Glu Lys Ser Pro Val  Leu Pro Asn 
    1640                 1645                 1650             


Thr Pro  Pro Thr Thr Leu Tyr  Ser Ser Thr Thr Arg  Thr Arg Thr 
    1655                 1660                 1665             


Ser Leu  Glu Glu Val Glu Gly  Arg Cys Ser Glu Arg  Asp Ala Arg 
    1670                 1675                 1680             


Leu Gly  Leu Cys Ala Arg Ser  Asn Asp Ala Val Pro  Ala Ala Pro 
    1685                 1690                 1695             


Gly Glu  Gly Leu His Ile Ser  
    1700                 1705 


<210>  849
<211>  741
<212>  PRT
<213>  Homo Sapiens

<400>  849

Glu Ala Phe Leu Val Phe Thr Ser Arg Ala Ala Ile His Arg Ile Ser 
1               5                   10                  15      


Leu Glu Thr Asn Asn Asn Asp Val Ala Ile Pro Leu Thr Gly Val Lys 
            20                  25                  30          


Glu Ala Ser Ala Leu Asp Phe Asp Val Ser Asn Asn His Ile Tyr Trp 
        35                  40                  45              


Thr Asp Val Ser Leu Lys Thr Ile Ser Arg Ala Phe Met Asn Gly Ser 
    50                  55                  60                  


Ser Val Glu His Val Val Glu Phe Gly Leu Asp Tyr Pro Glu Gly Met 
65                  70                  75                  80  


Ala Val Asp Trp Met Gly Lys Asn Leu Tyr Trp Ala Asp Thr Gly Thr 
                85                  90                  95      


Asn Arg Ile Glu Val Ala Arg Leu Asp Gly Gln Phe Arg Gln Val Leu 
            100                 105                 110         


Val Trp Arg Asp Leu Asp Asn Pro Arg Ser Leu Ala Leu Asp Pro Thr 
        115                 120                 125             


Lys Gly Tyr Ile Tyr Trp Thr Glu Trp Gly Gly Lys Pro Arg Ile Val 
    130                 135                 140                 


Arg Ala Phe Met Asp Gly Thr Asn Cys Met Thr Leu Val Asp Lys Val 
145                 150                 155                 160 


Gly Arg Ala Asn Asp Leu Thr Ile Asp Tyr Ala Asp Gln Arg Leu Tyr 
                165                 170                 175     


Trp Thr Asp Leu Asp Thr Asn Met Ile Glu Ser Ser Asn Met Leu Gly 
            180                 185                 190         


Gln Glu Arg Val Val Ile Ala Asp Asp Leu Pro His Pro Phe Gly Leu 
        195                 200                 205             


Thr Gln Tyr Ser Asp Tyr Ile Tyr Trp Thr Asp Trp Asn Leu His Ser 
    210                 215                 220                 


Ile Glu Arg Ala Asp Lys Thr Ser Gly Arg Asn Arg Thr Leu Ile Gln 
225                 230                 235                 240 


Gly His Leu Asp Phe Val Met Asp Ile Leu Val Phe His Ser Ser Arg 
                245                 250                 255     


Gln Asp Gly Leu Asn Asp Cys Met His Asn Asn Gly Gln Cys Gly Gln 
            260                 265                 270         


Leu Cys Leu Ala Ile Pro Gly Gly His Arg Cys Gly Cys Ala Ser His 
        275                 280                 285             


Tyr Thr Leu Asp Pro Ser Ser Arg Asn Cys Ser Pro Pro Thr Thr Phe 
    290                 295                 300                 


Leu Leu Phe Ser Gln Lys Ser Ala Ile Ser Arg Met Ile Pro Asp Asp 
305                 310                 315                 320 


Gln His Ser Pro Asp Leu Ile Leu Pro Leu His Gly Leu Arg Asn Val 
                325                 330                 335     


Lys Ala Ile Asp Tyr Asp Pro Leu Asp Lys Phe Ile Tyr Trp Val Asp 
            340                 345                 350         


Gly Arg Gln Asn Ile Lys Arg Ala Lys Asp Asp Gly Thr Gln Pro Phe 
        355                 360                 365             


Val Leu Thr Ser Leu Ser Gln Gly Gln Asn Pro Asp Arg Gln Pro His 
    370                 375                 380                 


Asp Leu Ser Ile Asp Ile Tyr Ser Arg Thr Leu Phe Trp Thr Cys Glu 
385                 390                 395                 400 


Ala Thr Asn Thr Ile Asn Val His Arg Leu Ser Gly Glu Ala Met Gly 
                405                 410                 415     


Val Val Leu Arg Gly Asp Arg Asp Lys Pro Arg Ala Ile Val Val Asn 
            420                 425                 430         


Ala Glu Arg Gly Tyr Leu Tyr Phe Thr Asn Met Gln Asp Arg Ala Ala 
        435                 440                 445             


Lys Ile Glu Arg Ala Ala Leu Asp Gly Thr Glu Arg Glu Val Leu Phe 
    450                 455                 460                 


Thr Thr Gly Leu Ile Arg Pro Val Ala Leu Val Val Asp Asn Thr Leu 
465                 470                 475                 480 


Gly Lys Leu Phe Trp Val Asp Ala Asp Leu Lys Arg Ile Glu Ser Cys 
                485                 490                 495     


Asp Leu Ser Gly Ala Asn Arg Leu Thr Leu Glu Asp Ala Asn Ile Val 
            500                 505                 510         


Gln Pro Leu Gly Leu Thr Ile Leu Gly Lys His Leu Tyr Trp Ile Asp 
        515                 520                 525             


Arg Gln Gln Gln Met Ile Glu Arg Val Glu Lys Thr Thr Gly Asp Lys 
    530                 535                 540                 


Arg Thr Arg Ile Gln Gly Arg Val Ala His Leu Thr Gly Ile His Ala 
545                 550                 555                 560 


Val Glu Glu Val Ser Leu Glu Glu Phe Ser Ala His Pro Cys Ala Arg 
                565                 570                 575     


Asp Asn Gly Gly Cys Ser His Ile Cys Ile Ala Lys Gly Asp Gly Thr 
            580                 585                 590         


Pro Arg Cys Ser Cys Pro Val His Leu Val Leu Leu Gln Asn Leu Leu 
        595                 600                 605             


Thr Cys Gly Glu Pro Pro Thr Cys Ser Pro Asp Gln Phe Ala Cys Ala 
    610                 615                 620                 


Thr Gly Glu Ile Asp Cys Ile Pro Gly Ala Trp Arg Cys Asp Gly Phe 
625                 630                 635                 640 


Pro Glu Cys Asp Asp Gln Ser Asp Glu Glu Gly Cys Pro Val Cys Ser 
                645                 650                 655     


Ala Ala Gln Phe Pro Cys Ala Arg Gly Gln Cys Val Asp Leu Arg Leu 
            660                 665                 670         


Arg Cys Asp Gly Glu Ala Asp Cys Gln Asp Arg Ser Asp Glu Ala Asp 
        675                 680                 685             


Cys Asp Ala Ile Cys Leu Pro Asn Gln Phe Arg Cys Ala Ser Gly Gln 
    690                 695                 700                 


Cys Val Leu Ile Lys Gln Gln Cys Asp Ser Phe Pro Asp Cys Ile Asp 
705                 710                 715                 720 


Gly Ser Asp Glu Leu Met Cys Glu Ile Thr Lys Pro Pro Ser Asp Asp 
                725                 730                 735     


Ser Pro Ala His Ser 
            740     


<210>  850
<211>  1351
<212>  PRT
<213>  Homo Sapiens

<400>  850

Ala Pro Leu Leu Leu Tyr Ala Asn Arg Arg Asp Leu Arg Leu Val Asp 
1               5                   10                  15      


Ala Thr Asn Gly Lys Glu Asn Ala Thr Ile Val Val Gly Gly Leu Glu 
            20                  25                  30          


Asp Ala Ala Ala Val Asp Phe Val Phe Ser His Gly Leu Ile Tyr Trp 
        35                  40                  45              


Ser Asp Val Ser Glu Glu Ala Ile Lys Arg Thr Glu Phe Asn Lys Thr 
    50                  55                  60                  


Glu Ser Val Gln Asn Val Val Val Ser Gly Leu Leu Ser Pro Asp Gly 
65                  70                  75                  80  


Leu Ala Cys Asp Trp Leu Gly Glu Lys Leu Tyr Trp Thr Asp Ser Glu 
                85                  90                  95      


Thr Asn Arg Ile Glu Val Ser Asn Leu Asp Gly Ser Leu Arg Lys Val 
            100                 105                 110         


Leu Phe Trp Gln Glu Leu Asp Gln Pro Arg Ala Ile Ala Leu Asp Pro 
        115                 120                 125             


Ser Ser Gly Phe Met Tyr Trp Thr Asp Trp Gly Glu Val Pro Lys Ile 
    130                 135                 140                 


Glu Arg Ala Gly Met Asp Gly Ser Ser Arg Phe Ile Ile Ile Asn Ser 
145                 150                 155                 160 


Glu Ile Tyr Trp Pro Asn Gly Leu Thr Leu Asp Tyr Glu Glu Gln Lys 
                165                 170                 175     


Leu Tyr Trp Ala Asp Ala Lys Leu Asn Phe Ile His Lys Ser Asn Leu 
            180                 185                 190         


Asp Gly Thr Asn Arg Gln Ala Val Val Lys Gly Ser Leu Pro His Pro 
        195                 200                 205             


Phe Ala Leu Thr Leu Phe Glu Asp Ile Leu Tyr Trp Thr Asp Trp Ser 
    210                 215                 220                 


Thr His Ser Ile Leu Ala Cys Asn Lys Tyr Thr Gly Glu Gly Leu Arg 
225                 230                 235                 240 


Glu Ile His Ser Asp Ile Phe Ser Pro Met Asp Ile His Ala Phe Ser 
                245                 250                 255     


Gln Gln Arg Gln Pro Asn Ala Thr Asn Pro Cys Gly Ile Asp Asn Gly 
            260                 265                 270         


Gly Cys Ser His Leu Cys Leu Met Ser Pro Val Lys Pro Phe Tyr Gln 
        275                 280                 285             


Cys Ala Cys Pro Thr Gly Val Lys Leu Leu Glu Asn Gly Lys Thr Cys 
    290                 295                 300                 


Lys Asp Gly Ala Thr Glu Leu Leu Leu Leu Ala Arg Arg Thr Asp Leu 
305                 310                 315                 320 


Arg Arg Ile Ser Leu Asp Thr Pro Asp Phe Thr Asp Ile Val Leu Gln 
                325                 330                 335     


Leu Glu Asp Ile Arg His Ala Ile Ala Ile Asp Tyr Asp Pro Val Glu 
            340                 345                 350         


Gly Tyr Ile Tyr Trp Thr Asp Asp Glu Val Arg Ala Ile Arg Arg Ser 
        355                 360                 365             


Phe Ile Asp Gly Ser Gly Ser Gln Phe Val Val Thr Ala Gln Ile Ala 
    370                 375                 380                 


His Pro Asp Gly Ile Ala Val Asp Trp Val Ala Arg Asn Leu Tyr Trp 
385                 390                 395                 400 


Thr Asp Thr Gly Thr Asp Arg Ile Glu Val Thr Arg Leu Asn Gly Thr 
                405                 410                 415     


Met Arg Lys Ile Leu Ile Ser Glu Asp Leu Glu Glu Pro Arg Ala Ile 
            420                 425                 430         


Val Leu Asp Pro Met Val Gly Tyr Met Tyr Trp Thr Asp Trp Gly Glu 
        435                 440                 445             


Ile Pro Lys Ile Glu Arg Ala Ala Leu Asp Gly Ser Asp Arg Val Val 
    450                 455                 460                 


Leu Val Asn Thr Ser Leu Gly Trp Pro Asn Gly Leu Ala Leu Asp Tyr 
465                 470                 475                 480 


Asp Glu Gly Lys Ile Tyr Trp Gly Asp Ala Lys Thr Asp Lys Ile Glu 
                485                 490                 495     


Val Met Asn Thr Asp Gly Thr Gly Arg Arg Val Leu Val Glu Asp Lys 
            500                 505                 510         


Ile Pro His Ile Phe Gly Phe Thr Leu Leu Gly Asp Tyr Val Tyr Trp 
        515                 520                 525             


Thr Asp Trp Gln Arg Arg Ser Ile Glu Arg Val His Lys Arg Ser Ala 
    530                 535                 540                 


Glu Arg Glu Val Ile Ile Asp Gln Leu Pro Asp Leu Met Gly Leu Lys 
545                 550                 555                 560 


Ala Thr Asn Val His Arg Val Ile Gly Ser Asn Pro Cys Ala Glu Glu 
                565                 570                 575     


Asn Gly Gly Cys Ser His Leu Cys Leu Tyr Arg Pro Gln Gly Leu Arg 
            580                 585                 590         


Cys Ala Cys Pro Ile Gly Phe Glu Leu Ile Ser Asp Met Lys Thr Cys 
        595                 600                 605             


Ile Val Pro Glu Ala Phe Leu Leu Phe Ser Arg Arg Ala Asp Ile Arg 
    610                 615                 620                 


Arg Ile Ser Leu Glu Thr Asn Asn Asn Asn Val Ala Ile Pro Leu Thr 
625                 630                 635                 640 


Gly Val Lys Glu Ala Ser Ala Leu Asp Phe Asp Val Thr Asp Asn Arg 
                645                 650                 655     


Ile Tyr Trp Thr Asp Ile Ser Leu Lys Thr Ile Ser Arg Ala Phe Met 
            660                 665                 670         


Asn Gly Ser Ala Leu Glu His Val Val Glu Phe Gly Leu Asp Tyr Pro 
        675                 680                 685             


Glu Gly Met Ala Val Asp Trp Leu Gly Lys Asn Leu Tyr Trp Ala Asp 
    690                 695                 700                 


Thr Gly Thr Asn Arg Ile Glu Val Ser Lys Leu Asp Gly Gln His Arg 
705                 710                 715                 720 


Gln Val Leu Val Trp Lys Asp Leu Asp Ser Pro Arg Ala Leu Ala Leu 
                725                 730                 735     


Asp Pro Ala Glu Gly Phe Met Tyr Trp Thr Glu Trp Gly Gly Lys Pro 
            740                 745                 750         


Lys Ile Asp Arg Ala Ala Met Asp Gly Ser Glu Arg Thr Thr Leu Val 
        755                 760                 765             


Pro Asn Val Gly Arg Ala Asn Gly Leu Thr Ile Asp Tyr Ala Lys Arg 
    770                 775                 780                 


Arg Leu Tyr Trp Thr Asp Leu Asp Thr Asn Leu Ile Glu Ser Ser Asn 
785                 790                 795                 800 


Met Leu Gly Leu Asn Arg Glu Val Ile Ala Asp Asp Leu Pro His Pro 
                805                 810                 815     


Phe Gly Leu Thr Gln Tyr Gln Asp Tyr Ile Tyr Trp Thr Asp Trp Ser 
            820                 825                 830         


Arg Arg Ser Ile Glu Arg Ala Asn Lys Thr Ser Gly Gln Asn Arg Thr 
        835                 840                 845             


Ile Ile Gln Gly His Leu Asp Tyr Val Met Asp Ile Leu Val Phe His 
    850                 855                 860                 


Ser Ser Arg Gln Ser Gly Trp Asn Glu Cys Ala Ser Ser Asn Gly His 
865                 870                 875                 880 


Cys Ser His Leu Cys Leu Ala Val Pro Val Gly Gly Phe Val Cys Gly 
                885                 890                 895     


Cys Pro Ala His Tyr Ser Leu Asn Ala Asp Asn Arg Thr Cys Ser Ala 
            900                 905                 910         


Pro Thr Thr Phe Leu Leu Phe Ser Gln Lys Ser Ala Ile Asn Arg Met 
        915                 920                 925             


Val Ile Asp Glu Gln Gln Ser Pro Asp Ile Ile Leu Pro Ile His Ser 
    930                 935                 940                 


Leu Arg Asn Val Arg Ala Ile Asp Tyr Asp Pro Leu Asp Lys Gln Leu 
945                 950                 955                 960 


Tyr Trp Ile Asp Ser Arg Gln Asn Met Ile Arg Lys Ala Gln Glu Asp 
                965                 970                 975     


Gly Ser Gln Gly Phe Thr Val Val Val Ser Ser Val Pro Ser Gln Asn 
            980                 985                 990         


Leu Glu Ile Gln Pro Tyr Asp Leu  Ser Ile Asp Ile Tyr  Ser Arg Tyr 
        995                 1000                 1005             


Ile Tyr  Trp Thr Cys Glu Ala  Thr Asn Val Ile Asn  Val Thr Arg 
    1010                 1015                 1020             


Leu Asp  Gly Arg Ser Val Gly  Val Val Leu Lys Gly  Glu Gln Asp 
    1025                 1030                 1035             


Arg Pro  Arg Ala Val Val Val  Asn Pro Glu Lys Gly  Tyr Met Tyr 
    1040                 1045                 1050             


Phe Thr  Asn Leu Gln Glu Arg  Ser Pro Lys Ile Glu  Arg Ala Ala 
    1055                 1060                 1065             


Leu Asp  Gly Thr Glu Arg Glu  Val Leu Phe Phe Ser  Gly Leu Ser 
    1070                 1075                 1080             


Lys Pro  Ile Ala Leu Ala Leu  Asp Ser Arg Leu Gly  Lys Leu Phe 
    1085                 1090                 1095             


Trp Ala  Asp Ser Asp Leu Arg  Arg Ile Glu Ser Ser  Asp Leu Ser 
    1100                 1105                 1110             


Gly Ala  Asn Arg Ile Val Leu  Glu Asp Ser Asn Ile  Leu Gln Pro 
    1115                 1120                 1125             


Val Gly  Leu Thr Val Phe Glu  Asn Trp Leu Tyr Trp  Ile Asp Lys 
    1130                 1135                 1140             


Gln Gln  Gln Met Ile Glu Lys  Ile Asp Met Thr Gly  Arg Glu Gly 
    1145                 1150                 1155             


Arg Thr  Lys Val Gln Ala Arg  Ile Ala Gln Leu Ser  Asp Ile His 
    1160                 1165                 1170             


Ala Val  Lys Glu Leu Asn Leu  Gln Glu Tyr Arg Gln  His Pro Cys 
    1175                 1180                 1185             


Ala Gln  Asp Asn Gly Gly Cys  Ser His Ile Cys Leu  Val Lys Gly 
    1190                 1195                 1200             


Asp Gly  Thr Thr Arg Cys Ser  Cys Pro Met His Leu  Val Leu Leu 
    1205                 1210                 1215             


Gln Asp  Glu Leu Ser Cys Gly  Glu Pro Pro Thr Cys  Ser Pro Gln 
    1220                 1225                 1230             


Gln Phe  Thr Cys Phe Thr Gly  Glu Ile Asp Cys Ile  Pro Val Ala 
    1235                 1240                 1245             


Trp Arg  Cys Asp Gly Phe Thr  Glu Cys Glu Asp His  Ser Asp Glu 
    1250                 1255                 1260             


Leu Asn  Cys Pro Val Cys Ser  Glu Ser Gln Phe Gln  Cys Ala Ser 
    1265                 1270                 1275             


Gly Gln  Cys Ile Asp Gly Ala  Leu Arg Cys Asn Gly  Asp Ala Asn 
    1280                 1285                 1290             


Cys Gln  Asp Lys Ser Asp Glu  Lys Asn Cys Glu Val  Leu Cys Leu 
    1295                 1300                 1305             


Ile Asp  Gln Phe Arg Cys Ala  Asn Gly Gln Cys Ile  Gly Lys His 
    1310                 1315                 1320             


Lys Lys  Cys Asp His Asn Val  Asp Cys Ser Asp Lys  Ser Asp Glu 
    1325                 1330                 1335             


Leu Asp  Cys Tyr Pro Thr Glu  Glu Pro Ala Pro Gln  Ala 
    1340                 1345                 1350     


<210>  851
<211>  785
<212>  PRT
<213>  Homo Sapiens

<400>  851

Gly Pro Ala Lys Glu Cys Glu Lys Asp Gln Phe Gln Cys Arg Asn Glu 
1               5                   10                  15      


Arg Cys Ile Pro Ser Val Trp Arg Cys Asp Glu Asp Asp Asp Cys Leu 
            20                  25                  30          


Asp His Ser Asp Glu Asp Asp Cys Pro Lys Lys Thr Cys Ala Asp Ser 
        35                  40                  45              


Asp Phe Thr Cys Asp Asn Gly His Cys Ile His Glu Arg Trp Lys Cys 
    50                  55                  60                  


Asp Gly Glu Glu Glu Cys Pro Asp Gly Ser Asp Glu Ser Glu Ala Thr 
65                  70                  75                  80  


Cys Thr Lys Gln Val Cys Pro Ala Glu Lys Leu Ser Cys Gly Pro Thr 
                85                  90                  95      


Ser His Lys Cys Val Pro Ala Ser Trp Arg Cys Asp Gly Glu Lys Asp 
            100                 105                 110         


Cys Glu Gly Gly Ala Asp Glu Ala Gly Cys Ala Thr Leu Cys Ala Pro 
        115                 120                 125             


His Glu Phe Gln Cys Gly Asn Arg Ser Cys Leu Ala Ala Val Phe Val 
    130                 135                 140                 


Cys Asp Gly Asp Asp Asp Cys Gly Asp Gly Ser Asp Glu Arg Gly Cys 
145                 150                 155                 160 


Ala Asp Pro Ala Cys Gly Pro Arg Glu Phe Arg Cys Gly Gly Asp Gly 
                165                 170                 175     


Gly Gly Ala Cys Ile Pro Glu Arg Trp Val Cys Asp Arg Gln Phe Asp 
            180                 185                 190         


Cys Glu Asp Arg Ser Asp Glu Ala Ala Glu Leu Cys Gly Arg Pro Gly 
        195                 200                 205             


Pro Gly Ala Thr Ser Ala Pro Ala Ala Cys Ala Thr Ala Ser Gln Phe 
    210                 215                 220                 


Ala Cys Arg Ser Gly Glu Cys Val His Leu Gly Trp Arg Cys Asp Gly 
225                 230                 235                 240 


Asp Arg Asp Cys Lys Asp Lys Ser Asp Glu Ala Asp Cys Pro Leu Gly 
                245                 250                 255     


Thr Cys Arg Gly Asp Glu Phe Gln Cys Gly Asp Gly Thr Cys Val Leu 
            260                 265                 270         


Ala Ile Lys His Cys Asn Gln Glu Gln Asp Cys Pro Asp Gly Ser Asp 
        275                 280                 285             


Glu Ala Gly Cys Leu Gln Gly Leu Asn Glu Cys Leu His Asn Asn Gly 
    290                 295                 300                 


Gly Cys Ser His Ile Cys Thr Asp Leu Lys Ile Gly Phe Glu Cys Thr 
305                 310                 315                 320 


Cys Pro Ala Gly Phe Gln Leu Leu Asp Gln Lys Thr Cys Gly Asp Ile 
                325                 330                 335     


Asp Glu Cys Lys Asp Pro Asp Ala Cys Ser Gln Ile Cys Val Asn Tyr 
            340                 345                 350         


Lys Gly Tyr Phe Lys Cys Glu Cys Tyr Pro Gly Tyr Glu Met Asp Leu 
        355                 360                 365             


Leu Thr Lys Asn Cys Lys Ala Ala Ala Gly Lys Ser Pro Ser Leu Ile 
    370                 375                 380                 


Phe Thr Asn Arg His Glu Val Arg Arg Ile Asp Leu Val Lys Arg Asn 
385                 390                 395                 400 


Tyr Ser Arg Leu Ile Pro Met Leu Lys Asn Val Val Ala Leu Asp Val 
                405                 410                 415     


Glu Val Ala Thr Asn Arg Ile Tyr Trp Cys Asp Leu Ser Tyr Arg Lys 
            420                 425                 430         


Ile Tyr Ser Ala Tyr Met Asp Lys Ala Ser Asp Pro Lys Glu Gln Glu 
        435                 440                 445             


Val Leu Ile Asp Glu Gln Leu His Ser Pro Glu Gly Leu Ala Val Asp 
    450                 455                 460                 


Trp Val His Lys His Ile Tyr Trp Thr Asp Ser Gly Asn Lys Thr Ile 
465                 470                 475                 480 


Ser Val Ala Thr Val Asp Gly Gly Arg Arg Arg Thr Leu Phe Ser Arg 
                485                 490                 495     


Asn Leu Ser Glu Pro Arg Ala Ile Ala Val Asp Pro Leu Arg Gly Phe 
            500                 505                 510         


Met Tyr Trp Ser Asp Trp Gly Asp Gln Ala Lys Ile Glu Lys Ser Gly 
        515                 520                 525             


Leu Asn Gly Val Asp Arg Gln Thr Leu Val Ser Asp Asn Ile Glu Trp 
    530                 535                 540                 


Pro Asn Gly Ile Thr Leu Asp Leu Leu Ser Gln Arg Leu Tyr Trp Val 
545                 550                 555                 560 


Asp Ser Lys Leu His Gln Leu Ser Ser Ile Asp Phe Ser Gly Gly Asn 
                565                 570                 575     


Arg Lys Thr Leu Ile Ser Ser Thr Asp Phe Leu Ser His Pro Phe Gly 
            580                 585                 590         


Ile Ala Val Phe Glu Asp Lys Val Phe Trp Thr Asp Leu Glu Asn Glu 
        595                 600                 605             


Ala Ile Phe Ser Ala Asn Arg Leu Asn Gly Leu Glu Ile Ser Ile Leu 
    610                 615                 620                 


Ala Glu Asn Leu Asn Asn Pro His Asp Ile Val Ile Phe His Glu Leu 
625                 630                 635                 640 


Lys Gln Pro Arg Ala Pro Asp Ala Cys Glu Leu Ser Val Gln Pro Asn 
                645                 650                 655     


Gly Gly Cys Glu Tyr Leu Cys Leu Pro Ala Pro Gln Ile Ser Ser His 
            660                 665                 670         


Ser Pro Lys Tyr Thr Cys Ala Cys Pro Asp Thr Met Trp Leu Gly Pro 
        675                 680                 685             


Asp Met Lys Arg Cys Tyr Arg Ala Pro Gln Ser Thr Ser Thr Thr Thr 
    690                 695                 700                 


Leu Ala Ser Thr Met Thr Arg Thr Val Pro Ala Thr Thr Arg Ala Pro 
705                 710                 715                 720 


Gly Thr Thr Val His Arg Ser Thr Tyr Gln Asn His Ser Thr Glu Thr 
                725                 730                 735     


Pro Ser Leu Thr Ala Ala Val Pro Ser Ser Val Ser Val Pro Arg Ala 
            740                 745                 750         


Pro Ser Ile Ser Pro Ser Thr Leu Ser Pro Ala Thr Ser Asn His Ser 
        755                 760                 765             


Gln His Tyr Ala Asn Glu Asp Ser Lys Met Gly Ser Thr Val Thr Ala 
    770                 775                 780                 


Ala 
785 


<210>  852
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  852

Tyr His Gly Cys Pro Ser Glu Cys Thr Cys Ser Arg Ala Ser Gln Val 
1               5                   10                  15      


Glu Cys Thr Gly Ala Arg Ile Val Ala Val Pro Thr Pro Leu Pro Trp 
            20                  25                  30          


Asn Ala Met Ser Leu Gln Ile Leu Asn Thr His Ile Thr Glu Leu Asn 
        35                  40                  45              


Glu Ser Pro Phe Leu Asn Ile Ser Ala Leu Ile Ala Leu Arg Ile Glu 
    50                  55                  60                  


Lys Asn Glu Leu Ser Arg Ile Thr Pro Gly Ala Phe Arg Asn Leu Gly 
65                  70                  75                  80  


Ser Leu Arg Tyr Leu Ser Leu Ala Asn Asn Lys Leu Gln Val Leu Pro 
                85                  90                  95      


Ile Gly Leu Phe Gln Gly Leu Asp Ser Leu Glu Ser Leu Leu Leu Ser 
            100                 105                 110         


Ser Asn Gln Leu Leu Gln Ile Gln Pro Ala His Phe Ser Gln Cys Ser 
        115                 120                 125             


Asn Leu Lys Glu Leu Gln Leu His Gly Asn His Leu Glu Tyr Ile Pro 
    130                 135                 140                 


Asp Gly Ala Phe Asp His Leu Val Gly Leu Thr Lys Leu Asn Leu Gly 
145                 150                 155                 160 


Lys Asn Ser Leu Thr His Ile Ser Pro Arg Val Phe Gln His Leu Gly 
                165                 170                 175     


Asn Leu Gln Val Leu Arg Leu Tyr Glu Asn Arg Leu Thr Asp Ile Pro 
            180                 185                 190         


Met Gly Thr Phe Asp Gly Leu Val Asn Leu Gln Glu Leu Ala Leu Gln 
        195                 200                 205             


Gln Asn Gln Ile Gly Leu Leu Ser Pro Gly Leu Phe His Asn Asn His 
    210                 215                 220                 


Asn Leu Gln Arg Leu Tyr Leu Ser Asn Asn His Ile Ser Gln Leu Pro 
225                 230                 235                 240 


Pro Ser Val Phe Met Gln Leu Pro Gln Leu Asn Arg Leu Thr Leu Phe 
                245                 250                 255     


Gly Asn Ser Leu Lys Glu Leu Ser Pro Gly Ile Phe Gly Pro Met Pro 
            260                 265                 270         


Asn Leu Arg Glu Leu Trp Leu Tyr Asp Asn His Ile Ser Ser Leu Pro 
        275                 280                 285             


Asp Asn Val Phe Ser Asn Leu Arg Gln Leu Gln Val Leu Ile Leu Ser 
    290                 295                 300                 


Arg Asn Gln Ile Ser Phe Ile Ser Pro Gly Ala Phe Asn Gly Leu Thr 
305                 310                 315                 320 


Glu Leu Arg Glu Leu Ser Leu His Thr Asn Ala Leu Gln Asp Leu Asp 
                325                 330                 335     


Gly Asn Val Phe Arg Met Leu Ala Asn Leu Gln Asn Ile Ser Leu Gln 
            340                 345                 350         


Asn Asn Arg Leu Arg Gln Leu Pro Gly Asn Ile Phe Ala Asn Val Asn 
        355                 360                 365             


Gly Leu Met Ala Ile Gln Leu Gln Asn Asn Gln Leu Glu Asn Leu Pro 
    370                 375                 380                 


Leu Gly Ile Phe Asp His Leu Gly Lys Leu Cys Glu Leu Arg Leu Tyr 
385                 390                 395                 400 


Asp Asn Pro Trp Arg Cys Asp Ser Asp Ile Leu Pro Leu Arg Asn Trp 
                405                 410                 415     


Leu Leu Leu Asn Gln Pro Arg Leu Gly Thr Asp Thr Val Pro Val Cys 
            420                 425                 430         


Phe Ser Pro Ala Asn Val Arg Gly Gln Ser Leu Ile Ile Ile Asn Val 
        435                 440                 445             


Asn Val Ala Val Pro Ser Val His Val Pro Glu Val Pro Ser Tyr Pro 
    450                 455                 460                 


Glu Thr Pro Trp Tyr Pro Asp Thr Pro Ser Tyr Pro Asp Thr Thr Ser 
465                 470                 475                 480 


Val Ser Ser Thr Thr Glu Leu Thr Ser Pro Val Glu Asp Tyr Thr Asp 
                485                 490                 495     


Leu Thr Thr Ile Gln Val Thr Asp Asp Arg Ser Val Trp Gly Met Thr 
            500                 505                 510         


Gln Ala Gln Ser Gly 
        515         


<210>  853
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  853

Arg Lys Ala Ser Pro Gly Ser Val Arg Ser Arg Val Asn His Gly Arg 
1               5                   10                  15      


Ala Gly Gly Gly Arg Arg Gly Ser Asn Pro Val Lys Arg Tyr Ala Pro 
            20                  25                  30          


Gly Leu Pro Cys Asp Val Tyr Thr Tyr Leu His Glu Lys Tyr Leu Asp 
        35                  40                  45              


Cys Gln Glu Arg Lys Leu Val Tyr Val Leu Pro Gly Trp Pro Gln Asp 
    50                  55                  60                  


Leu Leu His Met Leu Leu Ala Arg Asn Lys Ile Arg Thr Leu Lys Asn 
65                  70                  75                  80  


Asn Met Phe Ser Lys Phe Lys Lys Leu Lys Ser Leu Asp Leu Gln Gln 
                85                  90                  95      


Asn Glu Ile Ser Lys Ile Glu Ser Glu Ala Phe Phe Gly Leu Asn Lys 
            100                 105                 110         


Leu Thr Thr Leu Leu Leu Gln His Asn Gln Ile Lys Val Leu Thr Glu 
        115                 120                 125             


Glu Val Phe Ile Tyr Thr Pro Leu Leu Ser Tyr Leu Arg Leu Tyr Asp 
    130                 135                 140                 


Asn Pro Trp His Cys Thr Cys Glu Ile Glu Thr Leu Ile Ser Met Leu 
145                 150                 155                 160 


Gln Ile Pro Arg Asn Arg Asn Leu Gly Asn Tyr Ala Lys Cys Glu Ser 
                165                 170                 175     


Pro Gln Glu Gln Lys Asn Lys Lys Leu Arg Gln Ile Lys Ser Glu Gln 
            180                 185                 190         


Leu Cys Asn Glu Glu Glu Lys Glu Gln Leu Asp Pro Lys Pro Gln Val 
        195                 200                 205             


Ser Gly Arg Pro Pro Val Ile Lys Pro Glu Val Asp Ser Thr Phe Cys 
    210                 215                 220                 


His Asn Tyr Val Phe Pro Ile Gln Thr Leu Asp Cys Lys Arg Lys Glu 
225                 230                 235                 240 


Leu Lys Lys Val Pro Asn Asn Ile Pro Pro Asp Ile Val Lys Leu Asp 
                245                 250                 255     


Leu Ser Tyr Asn Lys Ile Asn Gln Leu Arg Pro Lys Glu Phe Glu Asp 
            260                 265                 270         


Val His Glu Leu Lys Lys Leu Asn Leu Ser Ser Asn Gly Ile Glu Phe 
        275                 280                 285             


Ile Asp Pro Ala Ala Phe Leu Gly Leu Thr His Leu Glu Glu Leu Asp 
    290                 295                 300                 


Leu Ser Asn Asn Ser Leu Gln Asn Phe Asp Tyr Gly Val Leu Glu Asp 
305                 310                 315                 320 


Leu Tyr Phe Leu Lys Leu Leu Trp Leu Arg Asp Asn Pro Trp Arg Cys 
                325                 330                 335     


Asp Tyr Asn Ile His Tyr Leu Tyr Tyr Trp Leu Lys His His Tyr Asn 
            340                 345                 350         


Val His Phe Asn Gly Leu Glu Cys Lys Thr Pro Glu Glu Tyr Lys Gly 
        355                 360                 365             


Trp Ser Val Gly Lys Tyr Ile Arg Ser Tyr Tyr Glu Glu Cys Pro Lys 
    370                 375                 380                 


Asp Lys Leu Pro Ala Tyr Pro Glu Ser Phe Asp Gln Asp Thr Glu Asp 
385                 390                 395                 400 


Asp Glu Trp Glu Lys Lys His Arg Asp His Thr Ala Lys Lys Gln Ser 
                405                 410                 415     


Val Ile Ile Thr Ile Val Gly 
            420             


<210>  854
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  854

Ser Lys Arg Glu Val Gln Cys Asn Phe Thr Glu Lys Asn Tyr Thr Leu 
1               5                   10                  15      


Ile Pro Ala Asp Ile Lys Lys Asp Val Thr Ile Leu Asp Leu Ser Tyr 
            20                  25                  30          


Asn Gln Ile Thr Leu Asn Gly Thr Asp Thr Arg Val Leu Gln Thr Tyr 
        35                  40                  45              


Phe Leu Leu Thr Glu Leu Tyr Leu Ile Glu Asn Lys Val Thr Ile Leu 
    50                  55                  60                  


His Asn Asn Gly Phe Gly Asn Leu Ser Ser Leu Glu Ile Leu Asn Ile 
65                  70                  75                  80  


Cys Arg Asn Ser Ile Tyr Val Ile Gln Gln Gly Ala Phe Leu Gly Leu 
                85                  90                  95      


Asn Lys Leu Lys Gln Leu Tyr Leu Cys Gln Asn Lys Ile Glu Gln Leu 
            100                 105                 110         


Asn Ala Asp Val Phe Val Pro Leu Arg Ser Leu Lys Leu Leu Asn Leu 
        115                 120                 125             


Gln Gly Asn Leu Ile Ser Tyr Leu Asp Val Pro Pro Leu Phe His Leu 
    130                 135                 140                 


Glu Leu Ile Thr Leu Tyr Gly Asn Leu Trp Asn Cys Ser Cys Ser Leu 
145                 150                 155                 160 


Phe Asn Leu Gln Asn Trp Leu Asn Thr Ser Asn Val Thr Leu Glu Asn 
                165                 170                 175     


Glu Asn Ile Thr Met Cys Ser Tyr Pro Asn Ser Leu Gln Ser Tyr Asn 
            180                 185                 190         


Ile Lys Thr Val Pro His Lys Ala Glu Cys His Ser Lys Phe Pro Ser 
        195                 200                 205             


Ser Val Thr Glu Asp Leu Tyr Ile His Phe Gln Pro Ile Ser Asn Ser 
    210                 215                 220                 


Ile Phe Asn Ser Ser Ser Asn Asn Leu Thr Arg Asn Ser Glu His Glu 
225                 230                 235                 240 


Pro Leu Gly Lys Ser Trp 
                245     


<210>  855
<211>  505
<212>  PRT
<213>  Homo Sapiens

<400>  855

Phe Cys Pro Ser Gln Cys Ser Cys Ser Leu His Ile Met Gly Asp Gly 
1               5                   10                  15      


Ser Lys Ala Arg Thr Val Val Cys Asn Asp Pro Asp Met Thr Leu Pro 
            20                  25                  30          


Pro Ala Ser Ile Pro Pro Asp Thr Ser Arg Leu Arg Leu Glu Arg Thr 
        35                  40                  45              


Ala Ile Arg Arg Val Pro Gly Glu Ala Phe Arg Pro Leu Gly Arg Leu 
    50                  55                  60                  


Glu Gln Leu Trp Leu Pro Tyr Asn Ala Leu Ser Glu Leu Asn Ala Leu 
65                  70                  75                  80  


Met Leu Arg Gly Leu Arg Arg Leu Arg Glu Leu Arg Leu Pro Gly Asn 
                85                  90                  95      


Arg Leu Ala Ala Phe Pro Trp Ala Ala Leu Arg Asp Ala Pro Lys Leu 
            100                 105                 110         


Arg Leu Leu Asp Leu Gln Ala Asn Arg Leu Ser Ala Val Pro Ala Glu 
        115                 120                 125             


Ala Ala Arg Phe Leu Glu Asn Leu Thr Phe Leu Asp Leu Ser Ser Asn 
    130                 135                 140                 


Gln Leu Met Arg Leu Pro Gln Glu Leu Ile Val Ser Trp Ala His Leu 
145                 150                 155                 160 


Glu Thr Gly Ile Phe Pro Pro Gly His His Pro Arg Arg Val Leu Gly 
                165                 170                 175     


Leu Gln Asp Asn Pro Trp Ala Cys Asp Cys Arg Leu Tyr Asp Leu Val 
            180                 185                 190         


His Leu Leu Asp Gly Trp Ala Pro Asn Leu Ala Phe Ile Glu Thr Glu 
        195                 200                 205             


Leu Arg Cys Ala Ser Pro Arg Ser Leu Ala Gly Val Ala Phe Ser Gln 
    210                 215                 220                 


Leu Glu Leu Arg Lys Cys Gln Gly Pro Glu Leu His Pro Gly Val Ala 
225                 230                 235                 240 


Ser Ile Arg Ser Leu Leu Gly Gly Thr Ala Leu Leu Arg Cys Gly Ala 
                245                 250                 255     


Thr Gly Val Pro Gly Pro Glu Met Ser Trp Arg Arg Ala Asn Gly Arg 
            260                 265                 270         


Pro Leu Asn Gly Thr Val His Gln Glu Val Ser Ser Asp Gly Thr Ser 
        275                 280                 285             


Trp Thr Leu Leu Gly Leu Pro Ala Val Ser His Leu Asp Ser Gly Asp 
    290                 295                 300                 


Tyr Ile Cys Gln Ala Lys Asn Phe Leu Gly Ala Ser Glu Thr Val Ile 
305                 310                 315                 320 


Ser Leu Ile Val Thr Glu Pro Pro Thr Ser Thr Glu His Ser Gly Ser 
                325                 330                 335     


Pro Gly Ala Leu Trp Ala Arg Thr Gly Gly Gly Gly Glu Ala Ala Ala 
            340                 345                 350         


Tyr Asn Asn Lys Leu Val Ala Arg His Val Pro Gln Ile Pro Lys Pro 
        355                 360                 365             


Ala Val Leu Ala Thr Gly Pro Ser Val Pro Ser Thr Lys Glu Glu Leu 
    370                 375                 380                 


Thr Leu Glu His Phe Gln Met Asp Ala Leu Gly Glu Leu Ser Asp Gly 
385                 390                 395                 400 


Arg Ala Gly Pro Ser Glu Ala Arg Met Val Arg Ser Val Lys Val Val 
                405                 410                 415     


Gly Asp Thr Tyr His Ser Val Ser Leu Val Trp Lys Ala Pro Gln Ala 
            420                 425                 430         


Lys Asn Thr Thr Ala Phe Ser Val Leu Tyr Ala Val Phe Gly Gln His 
        435                 440                 445             


Ser Met Arg Arg Val Ile Val Gln Pro Gly Lys Thr Arg Val Thr Ile 
    450                 455                 460                 


Thr Gly Leu Leu Pro Lys Thr Lys Tyr Val Ala Cys Val Cys Val Gln 
465                 470                 475                 480 


Gly Leu Val Pro Arg Lys Glu Gln Cys Val Ile Phe Ser Thr Asn Glu 
                485                 490                 495     


Val Val Asp Ala Glu Asn Thr Gln Gln 
            500                 505 


<210>  856
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  856

Ala Gly Cys Pro Ala Ala Cys Arg Cys Tyr Ser Ala Thr Val Glu Cys 
1               5                   10                  15      


Gly Ala Leu Arg Leu Arg Val Val Pro Leu Gly Ile Pro Pro Gly Thr 
            20                  25                  30          


Gln Thr Leu Phe Leu Gln Asp Asn Asn Ile Ala Arg Leu Glu Pro Gly 
        35                  40                  45              


Ala Leu Ala Pro Leu Ala Ala Leu Arg Arg Leu Tyr Leu His Asn Asn 
    50                  55                  60                  


Ser Leu Arg Ala Leu Glu Ala Gly Ala Phe Arg Ala Gln Pro Arg Leu 
65                  70                  75                  80  


Leu Glu Leu Ala Leu Thr Ser Asn Arg Leu Arg Gly Leu Arg Ser Gly 
                85                  90                  95      


Ala Phe Val Gly Leu Ala Gln Leu Arg Val Leu Tyr Leu Ala Gly Asn 
            100                 105                 110         


Gln Leu Ala Arg Leu Leu Asp Phe Thr Phe Leu His Leu Pro Arg Leu 
        115                 120                 125             


Gln Glu Leu His Leu Gln Glu Asn Ser Ile Glu Leu Leu Glu Asp Gln 
    130                 135                 140                 


Ala Leu Ala Gly Leu Ser Ser Leu Ala Leu Leu Asp Leu Ser Arg Asn 
145                 150                 155                 160 


Gln Leu Gly Thr Ile Ser Arg Glu Ala Leu Gln Pro Leu Ala Ser Leu 
                165                 170                 175     


Gln Val Leu Arg Leu Thr Glu Asn Pro Trp Arg Cys Asp Cys Ala Leu 
            180                 185                 190         


His Trp Leu Gly Ala Trp Ile Lys Glu Gly Gly Gln Arg Leu Leu Thr 
        195                 200                 205             


Ser Arg Asp Arg Lys Ile Met Cys Ala Glu Pro Pro Arg Leu Ala Leu 
    210                 215                 220                 


Gln Ser Leu Leu Asp Val Ser His Ser Ser Leu Ile Cys Ile Pro Pro 
225                 230                 235                 240 


Ser Val His Val Gln Pro Leu Glu Leu Thr Ala Asn Leu Gly Glu Asp 
                245                 250                 255     


Leu Arg Val Ala Cys Gln Ala Ser Gly Tyr Pro Gln Pro Leu Val Thr 
            260                 265                 270         


Trp Arg Lys Val Pro Gln Pro Arg Glu Gly Arg Pro Arg Ala Gln Ala 
        275                 280                 285             


Gln Leu Glu Gly Gly Leu Leu Gly Leu Gly Gly His Ser Ala Ser Asp 
    290                 295                 300                 


Thr Gly Ser Gly Met Leu Phe Leu Ser Asn Ile Thr Leu Ala His Ala 
305                 310                 315                 320 


Gly Lys Tyr Glu Cys Glu Ala Ser Asn Ala Gly Gly Ala Ala Arg Val 
                325                 330                 335     


Pro Phe Arg Leu Leu Val Asn Ala Ser Arg Gln Gln Pro Gln Gln Pro 
            340                 345                 350         


Ala Gln Pro Pro Pro Pro Ala Ala Arg Pro Ala Gly Ser Glu Pro Arg 
        355                 360                 365             


Pro Glu Ala Gly Ser Met Ala Phe Arg Ala Leu Gly Val Ala Thr Gln 
    370                 375                 380                 


Thr 
385 


<210>  857
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  857

Leu Glu Pro Ser Cys Thr Val Ser Ser Ala Asp Val Asp Trp Asn Ala 
1               5                   10                  15      


Glu Phe Ser Ala Thr Cys Leu Asn Phe Ser Gly Leu Ser Leu Ser Leu 
            20                  25                  30          


Pro His Asn Gln Ser Leu Arg Ala Ser Asn Val Ile Leu Leu Asp Leu 
        35                  40                  45              


Ser Gly Asn Gly Leu Arg Glu Leu Pro Val Thr Phe Phe Ala His Leu 
    50                  55                  60                  


Gln Lys Leu Glu Val Leu Asn Val Leu Arg Asn Pro Leu Ser Arg Val 
65                  70                  75                  80  


Asp Gly Ala Leu Ala Ala Arg Cys Asp Leu Asp Leu Gln Ala Asp Cys 
                85                  90                  95      


Asn Cys Ala Leu Glu Ser Trp His Asp Ile Arg Arg Asp Asn Cys Ser 
            100                 105                 110         


Gly Gln Lys Pro Leu Leu Cys Trp Asp Thr Thr Ser Ser Gln His Asn 
        115                 120                 125             


Leu Ser Ala Phe Leu Glu Val Ser Cys Ala Pro Gly Leu Ala Ser Ala 
    130                 135                 140                 


Thr 
145 


<210>  858
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  858

Gln Val Ser Ala Thr Ala Ser Pro Ser Gly Ser Leu Gly Ala Pro Asp 
1               5                   10                  15      


Cys Pro Glu Val Cys Thr Cys Val Pro Gly Gly Leu Ala Ser Cys Ser 
            20                  25                  30          


Ala Leu Ser Leu Pro Ala Val Pro Pro Gly Leu Ser Leu Arg Leu Arg 
        35                  40                  45              


Ala Leu Leu Leu Asp His Asn Arg Val Arg Ala Leu Pro Pro Gly Ala 
    50                  55                  60                  


Phe Ala Gly Ala Gly Ala Leu Gln Arg Leu Asp Leu Arg Glu Asn Gly 
65                  70                  75                  80  


Leu His Ser Val His Val Arg Ala Phe Trp Gly Leu Gly Ala Leu Gln 
                85                  90                  95      


Leu Leu Asp Leu Ser Ala Asn Gln Leu Glu Ala Leu Ala Pro Gly Thr 
            100                 105                 110         


Phe Ala Pro Leu Arg Ala Leu Arg Asn Leu Ser Leu Ala Gly Asn Arg 
        115                 120                 125             


Leu Ala Arg Leu Glu Pro Ala Ala Leu Gly Ala Leu Pro Leu Leu Arg 
    130                 135                 140                 


Ser Leu Ser Leu Gln Asp Asn Glu Leu Ala Ala Leu Ala Pro Gly Leu 
145                 150                 155                 160 


Leu Gly Arg Leu Pro Ala Leu Asp Ala Leu His Leu Arg Gly Asn Pro 
                165                 170                 175     


Trp Gly Cys Gly Cys Ala Leu Arg Pro Leu Cys Ala Trp Leu Arg Arg 
            180                 185                 190         


His Pro Leu Pro Ala Ser Glu Ala Glu Thr Val Leu Cys Val Trp Pro 
        195                 200                 205             


Gly Arg Leu Thr Leu Ser Pro Leu Thr Ala Phe Ser Asp Ala Ala Phe 
    210                 215                 220                 


Ser His Cys Ala Gln Pro Leu Ala Leu Arg Asp 
225                 230                 235 


<210>  859
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  859

Cys Pro Gln Pro Cys Arg Cys Pro Asp His Ala Gly Ala Val Ala Val 
1               5                   10                  15      


Phe Cys Ser Leu Arg Gly Leu Gln Glu Val Pro Glu Asp Ile Pro Ala 
            20                  25                  30          


Asn Thr Val Leu Leu Lys Leu Asp Ala Asn Lys Ile Ser His Leu Pro 
        35                  40                  45              


Asp Gly Ala Phe Gln His Leu His Arg Leu Arg Glu Leu Asp Leu Ser 
    50                  55                  60                  


His Asn Ala Ile Glu Ala Ile Gly Ser Ala Thr Phe Ala Gly Leu Ala 
65                  70                  75                  80  


Gly Gly Leu Arg Leu Leu Asp Leu Ser Tyr Asn Arg Ile Gln Arg Ile 
                85                  90                  95      


Pro Lys Asp Ala Leu Gly Lys Leu Ser Ala Lys Ile Arg Leu Ser His 
            100                 105                 110         


Asn Pro Leu His Cys Glu Cys Ala Leu Gln Glu Ala Leu Trp Glu Leu 
        115                 120                 125             


Lys Leu Asp Pro Asp Ser Val Asp Glu Ile Ala Cys His Thr Ser Val 
    130                 135                 140                 


Gln Glu Glu Phe Val Gly Lys Pro Leu Val Gln Ala Leu Asp Ala Gly 
145                 150                 155                 160 


Ala Ser Leu Cys Ser Val Pro His Arg Thr Thr Asp 
                165                 170         


<210>  860
<211>  608
<212>  PRT
<213>  Homo Sapiens

<400>  860

His Gln Asp Lys Val Pro Cys Lys Met Val Asp Lys Lys Val Ser Cys 
1               5                   10                  15      


Gln Val Leu Gly Leu Leu Gln Val Pro Ser Val Leu Pro Pro Asp Thr 
            20                  25                  30          


Glu Thr Leu Asp Leu Ser Gly Asn Gln Leu Arg Ser Ile Leu Ala Ser 
        35                  40                  45              


Pro Leu Gly Phe Tyr Thr Ala Leu Arg His Leu Asp Leu Ser Thr Asn 
    50                  55                  60                  


Glu Ile Ser Phe Leu Gln Pro Gly Ala Phe Gln Ala Leu Thr His Leu 
65                  70                  75                  80  


Glu His Leu Ser Leu Ala His Asn Arg Leu Ala Met Ala Thr Ala Leu 
                85                  90                  95      


Ser Ala Gly Gly Leu Gly Pro Leu Pro Arg Val Thr Ser Leu Asp Leu 
            100                 105                 110         


Ser Gly Asn Ser Leu Tyr Ser Gly Leu Leu Glu Arg Leu Leu Gly Glu 
        115                 120                 125             


Ala Pro Ser Leu His Thr Leu Ser Leu Ala Glu Asn Ser Leu Thr Arg 
    130                 135                 140                 


Leu Thr Arg His Thr Phe Arg Asp Met Pro Ala Leu Glu Gln Leu Asp 
145                 150                 155                 160 


Leu His Ser Asn Val Leu Met Asp Ile Glu Asp Gly Ala Phe Glu Gly 
                165                 170                 175     


Leu Pro Arg Leu Thr His Leu Asn Leu Ser Arg Asn Ser Leu Thr Cys 
            180                 185                 190         


Ile Ser Asp Phe Ser Leu Gln Gln Leu Arg Val Leu Asp Leu Ser Cys 
        195                 200                 205             


Asn Ser Ile Glu Ala Phe Gln Thr Ala Ser Gln Pro Gln Ala Glu Phe 
    210                 215                 220                 


Gln Leu Thr Trp Leu Asp Leu Arg Glu Asn Lys Leu Leu His Phe Pro 
225                 230                 235                 240 


Asp Leu Ala Ala Leu Pro Arg Leu Ile Tyr Leu Asn Leu Ser Asn Asn 
                245                 250                 255     


Leu Ile Arg Leu Pro Thr Gly Pro Pro Gln Asp Ser Lys Gly Ile His 
            260                 265                 270         


Ala Pro Ser Glu Gly Trp Ser Ala Leu Pro Leu Ser Ala Pro Ser Gly 
        275                 280                 285             


Asn Ala Ser Gly Arg Pro Leu Ser Gln Leu Leu Asn Leu Asp Leu Ser 
    290                 295                 300                 


Tyr Asn Glu Ile Glu Leu Ile Pro Asp Ser Phe Leu Glu His Leu Thr 
305                 310                 315                 320 


Ser Leu Cys Phe Leu Asn Leu Ser Arg Asn Cys Leu Arg Thr Phe Glu 
                325                 330                 335     


Ala Arg Arg Leu Gly Ser Leu Pro Cys Leu Met Leu Leu Asp Leu Ser 
            340                 345                 350         


His Asn Ala Leu Glu Thr Leu Glu Leu Gly Ala Arg Ala Leu Gly Ser 
        355                 360                 365             


Leu Arg Thr Leu Leu Leu Gln Gly Asn Ala Leu Arg Asp Leu Pro Pro 
    370                 375                 380                 


Tyr Thr Phe Ala Asn Leu Ala Ser Leu Gln Arg Leu Asn Leu Gln Gly 
385                 390                 395                 400 


Asn Arg Val Ser Pro Cys Gly Gly Pro Asp Glu Pro Gly Pro Ser Gly 
                405                 410                 415     


Cys Val Ala Phe Ser Gly Ile Thr Ser Leu Arg Ser Leu Ser Leu Val 
            420                 425                 430         


Asp Asn Glu Ile Glu Leu Leu Arg Ala Gly Ala Phe Leu His Thr Pro 
        435                 440                 445             


Leu Thr Glu Leu Asp Leu Ser Ser Asn Pro Gly Leu Glu Val Ala Thr 
    450                 455                 460                 


Gly Ala Leu Gly Gly Leu Glu Ala Ser Leu Glu Val Leu Ala Leu Gln 
465                 470                 475                 480 


Gly Asn Gly Leu Met Val Leu Gln Val Asp Leu Pro Cys Phe Ile Cys 
                485                 490                 495     


Leu Lys Arg Leu Asn Leu Ala Glu Asn Arg Leu Ser His Leu Pro Ala 
            500                 505                 510         


Trp Thr Gln Ala Val Ser Leu Glu Val Leu Asp Leu Arg Asn Asn Ser 
        515                 520                 525             


Phe Ser Leu Leu Pro Gly Ser Ala Met Gly Gly Leu Glu Thr Ser Leu 
    530                 535                 540                 


Arg Arg Leu Tyr Leu Gln Gly Asn Pro Leu Ser Cys Cys Gly Asn Gly 
545                 550                 555                 560 


Trp Leu Ala Ala Gln Leu His Gln Gly Arg Val Asp Val Asp Ala Thr 
                565                 570                 575     


Gln Asp Leu Ile Cys Arg Phe Ser Ser Gln Glu Glu Val Ser Leu Ser 
            580                 585                 590         


His Val Arg Pro Glu Asp Cys Glu Lys Gly Gly Leu Lys Asn Ile Asn 
        595                 600                 605             


<210>  861
<211>  1547
<212>  PRT
<213>  Homo Sapiens

<400>  861

Glu Ala Gln Pro Leu Glu Trp Val Lys Asp Pro Leu Gln Leu Thr Ser 
1               5                   10                  15      


Asn Pro Leu Gly Pro Pro Asp Ser Trp Ser Ser His Ser Ser His Phe 
            20                  25                  30          


Pro Arg Glu Ser Pro His Ala Pro Thr Leu Pro Ala Asp Pro Trp Asp 
        35                  40                  45              


Phe Asp His Leu Gly Pro Ser Ala Ser Ser Glu Met Pro Ala Pro Pro 
    50                  55                  60                  


Gln Glu Ser Thr Glu Asn Leu Val Pro Phe Leu Asp Thr Trp Asp Ser 
65                  70                  75                  80  


Ala Gly Glu Gln Pro Leu Glu Pro Glu Gln Phe Leu Ala Ser Gln Gln 
                85                  90                  95      


Asp Leu Lys Asp Lys Leu Ser Pro Gln Glu Arg Leu Pro Val Ser Pro 
            100                 105                 110         


Lys Lys Leu Lys Lys Asp Pro Ala Gln Arg Trp Ser Leu Ala Glu Ile 
        115                 120                 125             


Ile Gly Ile Thr Arg Gln Leu Ser Thr Pro Gln Ser Gln Lys Gln Thr 
    130                 135                 140                 


Leu Gln Asn Glu Tyr Ser Ser Thr Asp Thr Pro Tyr Pro Gly Ser Leu 
145                 150                 155                 160 


Pro Pro Glu Leu Arg Val Lys Ser Asp Glu Pro Pro Gly Pro Ser Glu 
                165                 170                 175     


Gln Val Gly Pro Ser Gln Phe His Leu Glu Pro Glu Thr Gln Asn Pro 
            180                 185                 190         


Glu Thr Leu Glu Asp Ile Gln Ser Ser Ser Leu Gln Gln Glu Ala Pro 
        195                 200                 205             


Ala Gln Leu Pro Gln Leu Leu Glu Glu Glu Pro Ser Ser Met Gln Gln 
    210                 215                 220                 


Glu Ala Pro Ala Leu Pro Pro Glu Ser Ser Met Glu Ser Leu Thr Leu 
225                 230                 235                 240 


Pro Asn His Glu Val Ser Val Gln Pro Pro Gly Glu Asp Gln Ala Tyr 
                245                 250                 255     


Tyr His Leu Pro Asn Ile Thr Val Lys Pro Ala Asp Val Glu Val Thr 
            260                 265                 270         


Ile Thr Ser Glu Pro Thr Asn Glu Thr Glu Ser Ser Gln Ala Gln Gln 
        275                 280                 285             


Glu Thr Pro Ile Gln Phe Pro Glu Glu Val Glu Pro Ser Ala Thr Gln 
    290                 295                 300                 


Gln Glu Ala Pro Ile Glu Pro Pro Val Ser Pro Met Glu His Glu Leu 
305                 310                 315                 320 


Ser Ile Ser Glu Gln Gln Gln Pro Val Gln Pro Ser Glu Ser Ser Arg 
                325                 330                 335     


Glu Val Glu Ser Ser Leu Thr Gln Gln Glu Thr Pro Gly Gln Pro Pro 
            340                 345                 350         


Glu His His Glu Val Thr Val Ser Pro Pro Gly His His Gln Thr His 
        355                 360                 365             


His Leu Asp Ser Pro Ser Val Ser Val Lys Pro Pro Asp Val Gln Leu 
    370                 375                 380                 


Thr Ile Ala Ala Glu Pro Ser Ala Glu Val Gly Thr Ser Leu Val His 
385                 390                 395                 400 


Gln Glu Ala Thr Ala Arg Leu Ser Gly Ser Gly Asn Asp Val Glu Pro 
                405                 410                 415     


Pro Ala Ile Gln His Gly Gly Pro Pro Leu Leu Pro Glu Ser Ser Glu 
            420                 425                 430         


Glu Ala Gly Pro Leu Ala Val Gln Gln Glu Thr Ser Phe Gln Ser Pro 
        435                 440                 445             


Glu Pro Ile Asn Asn Glu Asn Pro Ser Pro Thr Gln Gln Glu Ala Ala 
    450                 455                 460                 


Ala Glu His Pro Gln Thr Ala Glu Glu Gly Glu Ser Ser Leu Thr His 
465                 470                 475                 480 


Gln Glu Ala Pro Ala Gln Thr Pro Glu Phe Pro Asn Val Val Val Ala 
                485                 490                 495     


Gln Pro Pro Glu His Ser His Leu Thr Gln Ala Thr Val Gln Pro Leu 
            500                 505                 510         


Asp Leu Gly Phe Thr Ile Thr Pro Glu Ser Met Thr Glu Val Glu Leu 
        515                 520                 525             


Ser Pro Thr Met Lys Glu Thr Pro Thr Gln Pro Pro Lys Lys Val Val 
    530                 535                 540                 


Pro Gln Leu Arg Val Tyr Gln Gly Val Thr Asn Pro Thr Pro Gly Gln 
545                 550                 555                 560 


Asp Gln Ala Gln His Pro Val Ser Pro Ser Val Thr Val Gln Leu Leu 
                565                 570                 575     


Asp Leu Gly Leu Thr Ile Thr Pro Glu Pro Thr Thr Glu Val Gly His 
            580                 585                 590         


Ser Thr Ala Pro Lys Arg Thr Ile Val Ser Pro Lys His Pro Glu Val 
        595                 600                 605             


Thr Leu Pro His Pro Asp Gln Val Gln Thr Gln His Ser His Leu Thr 
    610                 615                 620                 


Arg Ala Thr Val Gln Pro Leu Asp Leu Gly Phe Thr Ile Thr Pro Lys 
625                 630                 635                 640 


Ser Met Thr Glu Val Glu Pro Ser Thr Ala Leu Met Thr Thr Ala Pro 
                645                 650                 655     


Pro Pro Gly His Pro Glu Val Thr Leu Pro Pro Ser Asp Lys Gly Gln 
            660                 665                 670         


Ala Gln His Ser His Leu Thr Gln Ala Thr Val Gln Pro Leu Asp Leu 
        675                 680                 685             


Glu Leu Thr Ile Thr Thr Lys Pro Thr Thr Glu Val Lys Pro Ser Pro 
    690                 695                 700                 


Thr Thr Glu Glu Thr Ser Thr Gln Pro Pro Asp Leu Gly Leu Ala Ile 
705                 710                 715                 720 


Ile Pro Glu Pro Thr Thr Glu Thr Gly His Ser Thr Ala Leu Glu Lys 
                725                 730                 735     


Thr Thr Ala Pro His Pro Asp Arg Val Gln Thr Leu His Gln Ser Leu 
            740                 745                 750         


Thr Glu Val Thr Gly Pro Pro Thr Glu Leu Glu Pro Ala Gln Asp Ser 
        755                 760                 765             


Leu Val Gln Ser Glu Ser Tyr Thr Gln Asn Lys Ala Leu Thr Ala Pro 
    770                 775                 780                 


Glu Glu His Lys Ala Ser Thr Ser Thr Asn Ile Cys Glu Leu Cys Thr 
785                 790                 795                 800 


Cys Gly Asp Glu Met Leu Ser Cys Ile Asp Leu Asn Pro Glu Gln Arg 
                805                 810                 815     


Leu Arg Gln Val Pro Val Pro Glu Pro Asn Thr His Asn Gly Thr Phe 
            820                 825                 830         


Thr Ile Leu Asn Phe Gln Gly Asn Tyr Ile Ser Tyr Ile Asp Gly Asn 
        835                 840                 845             


Val Trp Lys Ala Tyr Ser Trp Thr Glu Lys Leu Ile Leu Arg Glu Asn 
    850                 855                 860                 


Asn Leu Thr Glu Leu His Lys Asp Ser Phe Glu Gly Leu Leu Ser Leu 
865                 870                 875                 880 


Gln Tyr Leu Asp Leu Ser Cys Asn Lys Ile Gln Ser Ile Glu Arg His 
                885                 890                 895     


Thr Phe Glu Pro Leu Pro Phe Leu Lys Phe Ile Asn Leu Ser Cys Asn 
            900                 905                 910         


Val Ile Thr Glu Leu Ser Phe Gly Thr Phe Gln Ala Trp His Gly Met 
        915                 920                 925             


Gln Phe Leu His Lys Leu Ile Leu Asn His Asn Pro Leu Thr Thr Val 
    930                 935                 940                 


Glu Asp Pro Tyr Leu Phe Lys Leu Pro Ala Leu Lys Tyr Leu Asp Met 
945                 950                 955                 960 


Gly Thr Thr Leu Val Pro Leu Thr Thr Leu Lys Asn Ile Leu Met Met 
                965                 970                 975     


Thr Val Glu Leu Glu Lys Leu Ile Leu Pro Ser His Met Ala Cys Cys 
            980                 985                 990         


Leu Cys Gln Phe Lys Asn Ser Ile  Glu Ala Val Cys Lys  Thr Val Lys 
        995                 1000                 1005             


Leu His  Cys Asn Ser Ala Cys  Leu Thr Asn Thr Thr  His Cys Pro 
    1010                 1015                 1020             


Glu Glu  Ala Ser Val Gly Asn  Pro Glu Gly Ala Phe  Met Lys Val 
    1025                 1030                 1035             


Leu Gln  Ala Arg Lys Asn Tyr  Thr Ser Thr Glu Leu  Ile Val Glu 
    1040                 1045                 1050             


Pro Glu  Glu Pro Ser Asp Ser  Ser Gly Ile Asn Leu  Ser Gly Phe 
    1055                 1060                 1065             


Gly Ser  Glu Gln Leu Asp Thr  Asn Asp Glu Ser Asp  Phe Ile Ser 
    1070                 1075                 1080             


Thr Leu  Ser Tyr Ile Leu Pro  Tyr Phe Ser Ala Val  Asn Leu Asp 
    1085                 1090                 1095             


Val Lys  Ser Leu Leu Leu Pro  Phe Ile Lys Leu Pro  Thr Thr Gly 
    1100                 1105                 1110             


Asn Ser  Leu Ala Lys Ile Gln  Thr Val Gly Gln Asn  Arg Gln Arg 
    1115                 1120                 1125             


Val Lys  Arg Val Leu Met Gly  Pro Arg Ser Ile Gln  Lys Arg His 
    1130                 1135                 1140             


Phe Lys  Glu Val Gly Arg Gln  Ser Ile Arg Arg Glu  Gln Gly Ala 
    1145                 1150                 1155             


Gln Ala  Ser Val Glu Asn Ala  Ala Glu Glu Lys Arg  Leu Thr Ser 
    1160                 1165                 1170             


Pro Ala  Pro Arg Glu Val Glu  Gln Pro His Thr Gln  Gln Gly Pro 
    1175                 1180                 1185             


Glu Lys  Leu Ala Gly Asn Ala  Val Tyr Thr Lys Pro  Ser Phe Thr 
    1190                 1195                 1200             


Gln Glu  His Lys Ala Ala Val  Ser Val Leu Lys Pro  Phe Ser Lys 
    1205                 1210                 1215             


Gly Ala  Pro Ser Thr Ser Ser  Pro Ala Lys Ala Leu  Pro Gln Val 
    1220                 1225                 1230             


Arg Asp  Arg Ser Lys Asp Leu  Thr His Ala Ile Ser  Ile Leu Glu 
    1235                 1240                 1245             


Ser Ala  Lys Ala Arg Val Thr  Asn Thr Lys Thr Ser  Lys Pro Ile 
    1250                 1255                 1260             


Val His  Ala Arg Lys Lys Tyr  Arg Phe His Lys Thr  Arg Ser His 
    1265                 1270                 1275             


Val Thr  His Arg Thr Thr Lys  Val Lys Lys Ser Pro  Lys Val Arg 
    1280                 1285                 1290             


Lys Lys  Ser Tyr Leu Ser Arg  Leu Met Leu Ala Asn  Arg Leu Pro 
    1295                 1300                 1305             


Phe Ser  Ala Ala Lys Ser Leu  Ile Asn Ser Pro Ser  Gln Gly Ala 
    1310                 1315                 1320             


Phe Ser  Ser Leu Gly Asp Leu  Ser Pro Gln Glu Asn  Pro Phe Leu 
    1325                 1330                 1335             


Glu Val  Ser Ala Leu Ser Glu  His Phe Ile Gly Lys  Asn Asn Thr 
    1340                 1345                 1350             


Lys His  Thr Thr Ala Arg Asn  Ala Phe Glu Glu Asn  Asp Phe Met 
    1355                 1360                 1365             


Glu Asn  Thr Asn Met Pro Glu  Gly Thr Ile Ser Glu  Asn Thr Asn 
    1370                 1375                 1380             


Tyr Asn  His Pro Pro Glu Ala  Asp Ser Ala Gly Thr  Ala Phe Asn 
    1385                 1390                 1395             


Leu Gly  Pro Thr Val Lys Gln  Thr Glu Thr Lys Trp  Glu Tyr Asn 
    1400                 1405                 1410             


Asn Val  Gly Thr Asp Leu Ser  Pro Glu Pro Lys Ser  Phe Asn Tyr 
    1415                 1420                 1425             


Pro Leu  Leu Ser Ser Pro Gly  Asp Gln Phe Glu Ile  Gln Leu Thr 
    1430                 1435                 1440             


Gln Gln  Leu Gln Ser Leu Ile  Pro Asn Asn Asn Val  Arg Arg Leu 
    1445                 1450                 1455             


Ile Ala  His Val Ile Arg Thr  Leu Lys Met Asp Cys  Ser Gly Ala 
    1460                 1465                 1470             


His Val  Gln Val Thr Cys Ala  Lys Leu Ile Ser Arg  Thr Gly His 
    1475                 1480                 1485             


Leu Met  Lys Leu Leu Ser Gly  Gln Gln Glu Val Lys  Ala Ser Lys 
    1490                 1495                 1500             


Ile Glu  Trp Asp Thr Asp Gln  Trp Lys Ile Glu Asn  Tyr Ile Asn 
    1505                 1510                 1515             


Glu Ser  Thr Glu Ala Gln Ser  Glu Gln Lys Glu Lys  Ser Leu Glu 
    1520                 1525                 1530             


Leu Lys  Lys Glu Val Pro Gly  Tyr Gly Tyr Thr Asp  Lys Leu 
    1535                 1540                 1545         


<210>  862
<211>  1546
<212>  PRT
<213>  Homo Sapiens

<400>  862

Glu Ala Gln Pro Leu Glu Trp Val Lys Asp Pro Leu Gln Leu Thr Pro 
1               5                   10                  15      


Asn Pro Leu Gly Pro Pro Glu Pro Trp Ser Ser His Ser Ser His Phe 
            20                  25                  30          


Pro Arg Glu Ser Pro His Ala Pro Thr Leu Pro Ala Asp Pro Trp Asp 
        35                  40                  45              


Phe Asp His Leu Gly Pro Ser Ala Ser Ser Glu Met Pro Ala Pro Pro 
    50                  55                  60                  


Gln Glu Ser Thr Glu Asn Leu Val Pro Phe Leu Asp Thr Trp Asp Ser 
65                  70                  75                  80  


Ala Gly Glu Leu Pro Leu Glu Pro Glu Gln Phe Leu Ala Ser Gln Gln 
                85                  90                  95      


Asp Leu Lys Asp Lys Leu Ser Pro Gln Glu Arg Leu Pro Val Ser Pro 
            100                 105                 110         


Lys Lys Leu Lys Lys Asp Pro Ala Gln Arg Trp Ser Leu Ala Glu Ile 
        115                 120                 125             


Ile Gly Ile Ile His Gln Leu Ser Thr Pro Gln Ser Gln Lys Gln Thr 
    130                 135                 140                 


Leu Gln Asn Glu Tyr Ser Ser Thr Asp Thr Pro Tyr Pro Gly Ser Leu 
145                 150                 155                 160 


Pro Pro Glu Leu Arg Val Lys Ser Asp Glu Pro Pro Gly Pro Ser Glu 
                165                 170                 175     


Gln Val Gly Pro Ser Gln Phe His Leu Glu Pro Glu Thr Gln Asn Pro 
            180                 185                 190         


Glu Thr Leu Glu Asp Ile Gln Ser Ser Ser Leu Gln Gln Glu Ala Pro 
        195                 200                 205             


Ala Gln Leu Pro Gln Leu Leu Glu Glu Glu Pro Ser Ser Met Gln Gln 
    210                 215                 220                 


Glu Ala Pro Ala Leu Pro Pro Glu Ser Ser Met Glu Ser Leu Thr Leu 
225                 230                 235                 240 


Pro Asn His Glu Val Ser Val Gln Pro Pro Gly Glu Asp Gln Ala Tyr 
                245                 250                 255     


Tyr His Leu Pro Asn Ile Thr Val Lys Pro Ala Asp Val Glu Val Thr 
            260                 265                 270         


Ile Thr Ser Glu Pro Thr Asn Glu Thr Glu Ser Ser Gln Ala Gln Gln 
        275                 280                 285             


Glu Thr Pro Ile Gln Phe Pro Glu Glu Val Glu Pro Ser Ala Thr Gln 
    290                 295                 300                 


Gln Glu Ala Pro Ile Glu Pro Pro Val Pro Pro Met Glu His Glu Leu 
305                 310                 315                 320 


Ser Ile Ser Glu Gln Gln Gln Pro Val Gln Pro Ser Glu Ser Ser Arg 
                325                 330                 335     


Glu Val Glu Ser Ser Pro Thr Gln Gln Glu Thr Pro Gly Gln Pro Pro 
            340                 345                 350         


Glu His His Glu Val Thr Val Ser Pro Pro Gly His His Gln Thr His 
        355                 360                 365             


His Leu Ala Ser Pro Ser Val Ser Val Lys Pro Pro Asp Val Gln Leu 
    370                 375                 380                 


Thr Ile Ala Ala Glu Pro Ser Ala Glu Val Gly Thr Ser Leu Val His 
385                 390                 395                 400 


Gln Glu Ala Thr Thr Arg Leu Ser Gly Ser Gly Asn Asp Val Glu Pro 
                405                 410                 415     


Pro Ala Ile Gln His Gly Gly Pro Pro Leu Leu Pro Glu Ser Ser Glu 
            420                 425                 430         


Glu Ala Gly Pro Leu Ala Val Gln Gln Glu Thr Ser Phe Gln Ser Pro 
        435                 440                 445             


Glu Pro Ile Asn Asn Glu Asn Pro Ser Pro Thr Gln Gln Glu Ala Ala 
    450                 455                 460                 


Ala Glu His Pro Gln Thr Ala Glu Glu Gly Glu Ser Ser Leu Thr His 
465                 470                 475                 480 


Gln Glu Ala Pro Ala Gln Thr Pro Glu Phe Pro Asn Val Val Val Ala 
                485                 490                 495     


Gln Pro Pro Glu His Ser His Leu Thr Gln Ala Thr Val Gln Pro Leu 
            500                 505                 510         


Asp Leu Gly Phe Thr Ile Thr Pro Glu Ser Met Thr Glu Val Glu Leu 
        515                 520                 525             


Ser Pro Thr Met Lys Glu Thr Pro Thr Gln Pro Pro Lys Lys Val Val 
    530                 535                 540                 


Pro Gln Leu Arg Val Tyr Gln Gly Val Thr Asn Pro Thr Pro Gly Gln 
545                 550                 555                 560 


Asp Gln Ala Gln His Pro Val Ser Pro Ser Val Thr Val Gln Leu Leu 
                565                 570                 575     


Asp Leu Gly Leu Thr Ile Thr Pro Glu Pro Thr Thr Glu Val Gly His 
            580                 585                 590         


Ser Thr Pro Pro Lys Arg Thr Ile Val Ser Pro Lys His Pro Glu Val 
        595                 600                 605             


Thr Leu Pro His Pro Asp Gln Val Gln Thr Gln His Ser His Leu Thr 
    610                 615                 620                 


Arg Ala Thr Val Gln Pro Leu Asp Leu Gly Phe Thr Ile Thr Pro Lys 
625                 630                 635                 640 


Ser Met Thr Glu Val Glu Pro Ser Thr Ala Leu Met Thr Thr Ala Pro 
                645                 650                 655     


Pro Pro Gly His Pro Glu Val Thr Leu Pro Pro Ser Asp Lys Gly Gln 
            660                 665                 670         


Ala Gln His Ser His Leu Thr Gln Ala Thr Val Gln Pro Leu Asp Leu 
        675                 680                 685             


Glu Leu Thr Ile Thr Thr Lys Pro Thr Thr Glu Val Lys Pro Ser Pro 
    690                 695                 700                 


Thr Thr Glu Glu Thr Ser Thr Gln Leu Pro Asp Leu Gly Leu Ala Ile 
705                 710                 715                 720 


Ile Pro Glu Pro Thr Thr Glu Thr Gly His Ser Thr Ala Leu Glu Lys 
                725                 730                 735     


Thr Thr Ala Pro Arg Pro Asp Arg Val Gln Thr Leu His Arg Ser Leu 
            740                 745                 750         


Thr Glu Val Thr Gly Pro Pro Thr Glu Leu Glu Pro Ala Gln Asp Ser 
        755                 760                 765             


Leu Val Gln Ser Glu Ser Tyr Thr Gln Asn Lys Ala Leu Thr Ala Pro 
    770                 775                 780                 


Glu Glu His Lys Ala Ser Thr Ser Thr Asn Ile Cys Glu Leu Cys Thr 
785                 790                 795                 800 


Cys Gly Asp Glu Met Leu Ser Cys Ile Asp Leu Asn Pro Glu Gln Arg 
                805                 810                 815     


Leu Arg Gln Val Pro Val Pro Glu Pro Asn Thr His Asn Gly Thr Phe 
            820                 825                 830         


Thr Ile Leu Asn Phe Gln Gly Asn Tyr Ile Ser Tyr Ile Asp Gly Asn 
        835                 840                 845             


Val Trp Lys Ala Tyr Ser Trp Thr Glu Lys Leu Ile Leu Arg Glu Asn 
    850                 855                 860                 


Asn Leu Thr Glu Leu His Lys Asp Ser Phe Glu Gly Leu Leu Ser Leu 
865                 870                 875                 880 


Gln Tyr Leu Asp Leu Ser Cys Asn Lys Ile Gln Ser Ile Glu Arg His 
                885                 890                 895     


Thr Phe Glu Pro Leu Pro Phe Leu Lys Phe Ile Asn Leu Ser Cys Asn 
            900                 905                 910         


Val Ile Thr Glu Leu Ser Phe Gly Thr Phe Gln Ala Trp His Gly Met 
        915                 920                 925             


Gln Phe Leu His Lys Leu Ile Leu Asn His Asn Pro Leu Thr Thr Val 
    930                 935                 940                 


Glu Asp Pro Tyr Leu Phe Lys Leu Pro Ala Leu Lys Tyr Leu Asp Met 
945                 950                 955                 960 


Gly Thr Thr Leu Val Pro Leu Thr Thr Leu Lys Asn Ile Leu Met Met 
                965                 970                 975     


Thr Val Glu Leu Glu Lys Leu Ile Val Pro Ser His Met Ala Cys Cys 
            980                 985                 990         


Leu Cys Gln Phe Lys Asn Ser Ile  Glu Ala Val Cys Lys  Thr Val Lys 
        995                 1000                 1005             


Leu His  Cys Asn Ser Ala Cys  Leu Thr Asn Thr Thr  His Cys Pro 
    1010                 1015                 1020             


Glu Glu  Ala Ser Val Gly Asn  Pro Glu Gly Ala Phe  Met Lys Val 
    1025                 1030                 1035             


Leu Gln  Ala Arg Lys Asn Tyr  Thr Ser Thr Glu Leu  Thr Ile Glu 
    1040                 1045                 1050             


Pro Glu  Glu Pro Ser Asp Ser  Ser Gly Ile Asn Leu  Ser Gly Phe 
    1055                 1060                 1065             


Gly Ser  Glu Gln Leu Asp Thr  Asn Asp Glu Ser Asp  Val Thr Ser 
    1070                 1075                 1080             


Thr Leu  Ser Tyr Ile Leu Pro  Tyr Phe Ser Ala Val  Asn Leu Asp 
    1085                 1090                 1095             


Val Lys  Ser Leu Leu Leu Pro  Phe Ile Lys Leu Pro  Thr Thr Gly 
    1100                 1105                 1110             


Asn Ser  Leu Ala Lys Ile Gln  Thr Val Gly Lys Asn  Arg Gln Arg 
    1115                 1120                 1125             


Leu Asn  Arg Val Leu Met Gly  Pro Arg Ser Ile Gln  Lys Arg His 
    1130                 1135                 1140             


Phe Lys  Glu Val Gly Arg Gln  Ser Ile Arg Arg Glu  Gln Gly Ala 
    1145                 1150                 1155             


Gln Ala  Ser Val Glu Asn Thr  Ala Glu Glu Lys Arg  Leu Gly Ser 
    1160                 1165                 1170             


Pro Ala  Pro Arg Glu Leu Lys  Gln Pro His Thr Gln  Gln Gly Pro 
    1175                 1180                 1185             


Glu Lys  Leu Ala Gly Asn Ala  Val Tyr Thr Lys Pro  Ser Phe Thr 
    1190                 1195                 1200             


Gln Glu  His Lys Ala Ala Val  Ser Val Leu Lys Pro  Phe Ser Lys 
    1205                 1210                 1215             


Gly Ala  Pro Ser Thr Ser Ser  Pro Ala Lys Ala Leu  Pro Gln Val 
    1220                 1225                 1230             


Arg Asp  Arg Trp Lys Asp Leu  Thr His Ala Ile Ser  Ile Leu Glu 
    1235                 1240                 1245             


Ser Ala  Lys Ala Arg Val Thr  Asn Met Lys Thr Ser  Lys Pro Ile 
    1250                 1255                 1260             


Val His  Ser Arg Lys Lys Tyr  Arg Phe His Lys Thr  Arg Ser Arg 
    1265                 1270                 1275             


Met Thr  His Arg Thr Pro Lys  Val Lys Lys Ser Pro  Lys Val Arg 
    1280                 1285                 1290             


Lys Lys  Ser Tyr Leu Ser Arg  Leu Met Leu Ser Asn  Arg Leu Pro 
    1295                 1300                 1305             


Phe Ser  Ala Ala Lys Ser Leu  Ile Asn Ser Pro Ser  Gln Gly Ala 
    1310                 1315                 1320             


Phe Ser  Ser Leu Arg Asp Leu  Ser Pro Gln Glu Asn  Pro Phe Leu 
    1325                 1330                 1335             


Glu Val  Ser Ala Pro Ser Glu  His Phe Ile Glu Asn  Asn Asn Thr 
    1340                 1345                 1350             


Lys Asp  Thr Thr Ala Arg Asn  Ala Phe Glu Glu Asn  Val Phe Met 
    1355                 1360                 1365             


Glu Asn  Thr Asn Met Pro Glu  Gly Thr Ile Ser Glu  Asn Ala Asn 
    1370                 1375                 1380             


Tyr Asn  His Pro Pro Glu Ala  Asp Ser Ala Gly Thr  Ala Phe Asn 
    1385                 1390                 1395             


Leu Gly  Pro Thr Val Lys Gln  Thr Glu Thr Lys Trp  Glu Tyr Asn 
    1400                 1405                 1410             


Asn Val  Gly Thr Asp Leu Ser  Pro Glu Pro Lys Ser  Phe Asn Tyr 
    1415                 1420                 1425             


Pro Leu  Leu Ser Ser Pro Gly  Asp Gln Phe Glu Ile  Gln Leu Thr 
    1430                 1435                 1440             


Gln Gln  Leu Gln Ser Val Ile  Pro Asn Asn Asn Val  Arg Arg Leu 
    1445                 1450                 1455             


Ile Ala  His Val Ile Arg Thr  Leu Lys Met Asp Cys  Ser Gly Ala 
    1460                 1465                 1470             


His Val  Gln Val Thr Cys Ala  Lys Leu Val Ser Arg  Thr Gly His 
    1475                 1480                 1485             


Leu Met  Lys Leu Leu Ser Gly  Gln Gln Glu Val Lys  Ala Ser Lys 
    1490                 1495                 1500             


Ile Glu  Trp Asp Thr Asp Gln  Trp Lys Thr Glu Asn  Tyr Ile Asn 
    1505                 1510                 1515             


Glu Ser  Thr Glu Ala Gln Ser  Glu Gln Lys Glu Lys  Ser Leu Glu 
    1520                 1525                 1530             


Phe Thr  Lys Glu Leu Pro Gly  Tyr Gly Tyr Thr Lys  Lys 
    1535                 1540                 1545     


<210>  863
<211>  827
<212>  PRT
<213>  Homo Sapiens

<400>  863

Leu Val Trp Val Lys Asp Pro Leu Gln Leu Thr Ser Asn Pro Leu Gly 
1               5                   10                  15      


Pro Pro Glu Pro Trp Ser Ser Arg Ser Ser His Leu Pro Trp Glu Ser 
            20                  25                  30          


Pro His Ala Pro Ala Pro Pro Ala Ala Pro Gly Asp Phe Asp Tyr Leu 
        35                  40                  45              


Gly Pro Ser Ala Ser Ser Gln Met Ser Ala Leu Pro Gln Glu Pro Thr 
    50                  55                  60                  


Glu Asn Leu Ala Pro Phe Leu Lys Glu Leu Asp Ser Ala Gly Glu Leu 
65                  70                  75                  80  


Pro Leu Gly Pro Glu Pro Phe Leu Ala Ala His Gln Asp Leu Asn Asp 
                85                  90                  95      


Lys Arg Thr Pro Glu Glu Arg Leu Pro Glu Val Val Pro Leu Leu Asn 
            100                 105                 110         


Arg Asp Gln Asn Gln Ala Leu Val Gln Leu Pro Arg Leu Lys Trp Val 
        115                 120                 125             


Gln Thr Thr Asp Leu Asp Arg Ala Ala Gly His Gln Ala Asp Glu Ile 
    130                 135                 140                 


Leu Val Pro Leu Asp Ser Lys Val Ser Arg Pro Thr Lys Phe Val Val 
145                 150                 155                 160 


Ser Pro Lys Asn Leu Lys Lys Asp Leu Ala Glu Arg Trp Ser Leu Pro 
                165                 170                 175     


Glu Ile Val Gly Ile Pro His Gln Leu Ser Lys Pro Gln Arg Gln Lys 
            180                 185                 190         


Gln Thr Leu Pro Asp Asp Tyr Leu Ser Met Asp Thr Leu Tyr Pro Gly 
        195                 200                 205             


Ser Leu Pro Pro Glu Leu Arg Val Asn Ala Asp Glu Pro Pro Gly Pro 
    210                 215                 220                 


Pro Glu Gln Val Gly Leu Ser Gln Phe His Leu Glu Pro Lys Ser Gln 
225                 230                 235                 240 


Asn Pro Glu Thr Leu Glu Asp Ile Gln Ser Ser Ser Leu Gln Glu Glu 
                245                 250                 255     


Ala Pro Ala Gln Leu Leu Gln Leu Pro Gln Glu Val Glu Pro Ser Thr 
            260                 265                 270         


Gln Gln Glu Ala Pro Ala Leu Pro Pro Glu Ser Ser Met Glu Ser Leu 
        275                 280                 285             


Ala Gln Thr Pro Leu Asn His Glu Val Thr Val Gln Pro Pro Gly Glu 
    290                 295                 300                 


Asp Gln Ala His Tyr Asn Leu Pro Lys Phe Thr Val Lys Pro Ala Asp 
305                 310                 315                 320 


Val Glu Val Thr Met Thr Ser Glu Pro Lys Asn Glu Thr Glu Ser Thr 
                325                 330                 335     


Gln Ala Gln Gln Glu Ala Pro Ile Gln Pro Pro Glu Glu Ala Glu Pro 
            340                 345                 350         


Ser Ser Thr Ala Leu Arg Thr Thr Asp Pro Pro Pro Glu His Pro Glu 
        355                 360                 365             


Val Thr Leu Pro Pro Ser Asp Lys Gly Gln Ala Gln His Ser His Leu 
    370                 375                 380                 


Thr Glu Ala Thr Val Gln Pro Leu Asp Leu Glu Leu Ser Ile Thr Thr 
385                 390                 395                 400 


Glu Pro Thr Thr Glu Val Lys Pro Ser Pro Thr Thr Glu Glu Thr Ser 
                405                 410                 415     


Ala Gln Pro Pro Asp Pro Gly Leu Ala Ile Thr Pro Glu Pro Thr Thr 
            420                 425                 430         


Glu Ile Gly His Ser Thr Ala Leu Glu Lys Thr Arg Ala Pro His Pro 
        435                 440                 445             


Asp Gln Val Gln Thr Leu His Arg Ser Leu Thr Glu Val Thr Gly Pro 
    450                 455                 460                 


Pro Thr Lys Leu Glu Ser Ser Gln Asp Ser Leu Val Gln Ser Glu Thr 
465                 470                 475                 480 


Ala Pro Glu Glu Gln Lys Ala Ser Thr Ser Thr Asn Ile Cys Glu Leu 
                485                 490                 495     


Cys Thr Cys Gly Asp Glu Thr Leu Ser Cys Val Gly Leu Ser Pro Lys 
            500                 505                 510         


Gln Arg Leu Arg Gln Val Pro Val Pro Glu Pro Asp Thr Tyr Asn Gly 
        515                 520                 525             


Ile Phe Thr Thr Leu Asn Phe Gln Gly Asn Tyr Ile Ser Tyr Leu Asp 
    530                 535                 540                 


Gly Asn Val Trp Lys Ala Tyr Ser Trp Thr Glu Lys Leu Ile Leu Ser 
545                 550                 555                 560 


Glu Asn Tyr Leu Thr Glu Leu Pro Lys Asp Ser Phe Glu Gly Leu Leu 
                565                 570                 575     


Tyr Leu Gln Tyr Leu Ile Leu Asn Arg Asn Pro Leu Thr Thr Val Glu 
            580                 585                 590         


Asp Pro Tyr Leu Phe Glu Leu Pro Ala Leu Lys Tyr Leu Asp Met Gly 
        595                 600                 605             


Thr Thr His Ile Thr Leu Thr Thr Leu Lys Asn Ile Leu Thr Met Thr 
    610                 615                 620                 


Val Glu Leu Glu Lys Leu Ile Leu Pro Ser His Met Ala Cys Cys Leu 
625                 630                 635                 640 


Cys Gln Phe Lys Asn Ser Ile Glu Ala Val Cys Lys Thr Val Lys Leu 
                645                 650                 655     


His Cys Asn Thr Ala Cys Leu Thr Asn Ser Ile His Cys Pro Glu Glu 
            660                 665                 670         


Ala Ser Val Gly Asn Pro Glu Gly Ala Phe Met Lys Met Leu Gln Ala 
        675                 680                 685             


Arg Lys Gln His Met Ser Thr Gln Leu Thr Ile Glu Ser Glu Ala Pro 
    690                 695                 700                 


Ser Asp Ser Ser Gly Ile Asn Leu Ser Gly Phe Gly Gly Asp Gln Leu 
705                 710                 715                 720 


Glu Ile Gln Leu Thr Glu Gln Leu Arg Ser Leu Ile Pro Asn Glu Asp 
                725                 730                 735     


Val Arg Lys Phe Met Ser His Val Ile Arg Thr Leu Lys Met Glu Cys 
            740                 745                 750         


Ser Glu Thr His Val Gln Gly Ser Cys Ala Lys Leu Met Leu Arg Thr 
        755                 760                 765             


Gly Leu Leu Met Lys Leu Leu Ser Glu Gln Gln Glu Ala Lys Ala Leu 
    770                 775                 780                 


Asn Val Glu Trp Asp Thr Asp Gln Gln Lys Thr Asn Tyr Ile Asn Glu 
785                 790                 795                 800 


Asn Met Glu Gln Asn Glu Gln Lys Glu Gln Lys Ser Ser Glu Leu Met 
                805                 810                 815     


Lys Glu Val Pro Gly Asp Asp Tyr Lys Asn Lys 
            820                 825         


<210>  864
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  864

Cys Pro Ala Gly Cys Ala Cys Thr Asp Pro His Thr Val Asp Cys Arg 
1               5                   10                  15      


Asp Arg Gly Leu Pro Ser Val Pro Asp Pro Phe Pro Leu Asp Val Arg 
            20                  25                  30          


Lys Leu Leu Val Ala Gly Asn Arg Ile Gln Arg Ile Pro Glu Asp Phe 
        35                  40                  45              


Phe Ile Phe Tyr Gly Asp Leu Val Tyr Leu Asp Phe Arg Asn Asn Ser 
    50                  55                  60                  


Leu Arg Ser Leu Glu Glu Gly Thr Phe Ser Gly Ser Ala Lys Leu Val 
65                  70                  75                  80  


Phe Leu Asp Leu Ser Tyr Asn Asn Leu Thr Gln Leu Gly Ala Gly Ala 
                85                  90                  95      


Phe Arg Ser Ala Gly Arg Leu Val Lys Leu Ser Leu Ala Asn Asn Asn 
            100                 105                 110         


Leu Val Gly Val His Glu Asp Ala Phe Glu Thr Leu Glu Ser Leu Gln 
        115                 120                 125             


Val Leu Glu Leu Asn Asp Asn Asn Leu Arg Ser Leu Ser Val Ala Ala 
    130                 135                 140                 


Leu Ala Ala Leu Pro Ala Leu Arg Ser Leu Arg Leu Asp Gly Asn Pro 
145                 150                 155                 160 


Trp Leu Cys Asp Cys Asp Phe Ala His Leu Phe Ser Trp Ile Gln Glu 
                165                 170                 175     


Asn Ala Ser Lys Leu Pro Lys Gly Leu Asp Glu Ile Gln Cys Ser Leu 
            180                 185                 190         


Pro Met Glu Ser Arg Arg Ile Ser Leu Arg Glu Leu Ser Glu Ala Ser 
        195                 200                 205             


Phe Ser Glu Cys Arg Phe Ser Leu Ser Leu Thr Asp Leu Cys 
    210                 215                 220         


<210>  865
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  865

Cys Pro Lys Gly Cys Leu Cys Ser Ser Ser Gly Gly Leu Asn Val Thr 
1               5                   10                  15      


Cys Ser Asn Ala Asn Leu Lys Glu Ile Pro Arg Asp Leu Pro Pro Glu 
            20                  25                  30          


Thr Val Leu Leu Tyr Leu Asp Ser Asn Gln Ile Thr Ser Ile Pro Asn 
        35                  40                  45              


Glu Ile Phe Lys Asp Leu His Gln Leu Arg Val Leu Asn Leu Ser Lys 
    50                  55                  60                  


Asn Gly Ile Glu Phe Ile Asp Glu His Ala Phe Lys Gly Val Ala Glu 
65                  70                  75                  80  


Thr Leu Gln Thr Leu Asp Leu Ser Asp Asn Arg Ile Gln Ser Val His 
                85                  90                  95      


Lys Asn Ala Phe Asn Asn Leu Lys Ala Arg Ala Arg Ile Ala Asn Asn 
            100                 105                 110         


Pro Trp His Cys Asp Cys Thr Leu Gln Gln Val Leu Arg Ser Met Ala 
        115                 120                 125             


Ser Asn His Glu Thr Ala His Asn Val Ile Cys Lys Thr Ser Val Leu 
    130                 135                 140                 


Asp Glu His Ala Gly Arg Pro Phe Leu Asn Ala Ala Asn Asp Ala Asp 
145                 150                 155                 160 


Leu Cys Asn Leu Pro Lys Lys Thr Thr Asp Tyr 
                165                 170     


<210>  866
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  866

Val Pro Ser Pro Gln Val Pro Pro Arg Gly Cys Tyr Val Ala Lys Glu 
1               5                   10                  15      


Ala Gly Glu Arg Thr Phe Arg Cys Ser Gln Ala Gly Leu Ser Ala Val 
            20                  25                  30          


Pro Ser Gly Ile Pro Asn Asp Thr Arg Lys Leu Tyr Leu Asp Ala Asn 
        35                  40                  45              


Gln Leu Ala Ser Val Pro Ala Gly Ala Phe Gln His Leu Pro Val Leu 
    50                  55                  60                  


Glu Glu Leu Asp Leu Ser His Asn Ala Leu Ala His Leu Ser Gly Ala 
65                  70                  75                  80  


Ala Phe Gln Gly Leu Glu Gly Thr Leu Arg His Leu Asp Leu Ser Ala 
                85                  90                  95      


Asn Gln Leu Ala Ser Val Pro Val Glu Ala Phe Val Gly Leu Gln Ile 
            100                 105                 110         


Gln Val Asn Leu Ser Ala Asn Pro Trp His Cys Asp Cys Ala Leu Gln 
        115                 120                 125             


Glu Val Leu Arg Gln Val Arg Leu Val Pro Gly Thr Gly Thr Gly Ile 
    130                 135                 140                 


Val Cys Gly Ser Gly Ala Arg Pro Asp Leu Val Gly Gln Glu Phe Leu 
145                 150                 155                 160 


Leu Leu Ala Gly Glu Glu Glu Leu Cys Gly Ser Gly Trp Gly Gly Ala 
                165                 170                 175     


Arg Arg Ser Thr Asp Val Ala 
            180             


<210>  867
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  867

Ala Ser Ala Gly Pro Gln Asn Cys Pro Ser Val Cys Ser Cys Ser Asn 
1               5                   10                  15      


Gln Phe Ser Lys Val Val Cys Thr Arg Arg Gly Leu Ser Glu Val Pro 
            20                  25                  30          


Gln Gly Ile Pro Ser Asn Thr Arg Tyr Leu Asn Leu Met Glu Asn Asn 
        35                  40                  45              


Ile Gln Met Ile Gln Ala Asp Thr Phe Arg His Leu His His Leu Glu 
    50                  55                  60                  


Val Leu Gln Leu Gly Arg Asn Ser Ile Arg Gln Ile Glu Val Gly Ala 
65                  70                  75                  80  


Phe Asn Gly Leu Ala Ser Leu Asn Thr Leu Glu Leu Phe Asp Asn Trp 
                85                  90                  95      


Leu Thr Val Ile Pro Ser Gly Ala Phe Glu Tyr Leu Ser Lys Leu Arg 
            100                 105                 110         


Glu Leu Trp Leu Arg Asn Asn Pro Ile Glu Ser Ile Pro Ser Tyr Ala 
        115                 120                 125             


Phe Asn Arg Val Pro Ser Leu Met Arg Leu Asp Leu Gly Glu Leu Lys 
    130                 135                 140                 


Lys Leu Glu Tyr Ile Ser Glu Gly Ala Phe Glu Gly Leu Phe Asn Leu 
145                 150                 155                 160 


Lys Tyr Leu Asn Leu Gly Met Cys Asn Ile Lys Asp Met Pro Asn Leu 
                165                 170                 175     


Thr Pro Leu Val Gly Leu Glu Glu Leu Glu Met Ser Gly Asn His Phe 
            180                 185                 190         


Pro Glu Ile Arg Pro Gly Ser Phe His Gly Leu Ser Ser Leu Lys Lys 
        195                 200                 205             


Leu Trp Val Met Asn Ser Gln Val Ser Leu Ile Glu Arg Asn Ala Phe 
    210                 215                 220                 


Asp Gly Leu Ala Ser Leu Val Glu Leu Asn Leu Ala His Asn Asn Leu 
225                 230                 235                 240 


Ser Ser Leu Pro His Asp Leu Phe Thr Pro Leu Arg Tyr Leu Val Glu 
                245                 250                 255     


Leu His Leu His His Asn Pro Trp Asn Cys Asp Cys Asp Ile Leu Trp 
            260                 265                 270         


Leu Ala Trp Trp Leu Arg Glu Tyr Ile Pro Thr Asn Ser Thr Cys Cys 
        275                 280                 285             


Gly Arg Cys His Ala Pro Met His Met Arg Gly Arg Tyr Leu Val Glu 
    290                 295                 300                 


Val Asp Gln Ala Ser Phe Gln Cys Ser Ala Pro Phe Ile Met Asp Ala 
305                 310                 315                 320 


Pro Arg Asp Leu Asn Ile Ser Glu Gly Arg Met Ala Glu Leu Lys Cys 
                325                 330                 335     


Arg Thr Pro Pro Met Ser Ser Val Lys Trp Leu Leu Pro Asn Gly Thr 
            340                 345                 350         


Val Leu Ser His Ala Ser Arg His Pro Arg Ile Ser Val Leu Asn Asp 
        355                 360                 365             


Gly Thr Leu Asn Phe Ser His Val Leu Leu Ser Asp Thr Gly Val Tyr 
    370                 375                 380                 


Thr Cys Met Val Thr Asn Val Ala Gly Asn Ser Asn Ala Ser Ala Tyr 
385                 390                 395                 400 


Leu Asn Val Ser Thr Ala Glu Leu Asn Thr Ser Asn Tyr Ser Phe Phe 
                405                 410                 415     


Thr Thr Val Thr Val Glu Thr Thr Glu Ile Ser Pro Glu Asp Thr Thr 
            420                 425                 430         


Arg Lys Tyr Lys Pro Val Pro Thr Thr Ser Thr Gly Tyr Gln Pro Ala 
        435                 440                 445             


Tyr Thr Thr Ser Thr Thr Val Leu Ile Gln Thr Thr Arg Val Pro Lys 
    450                 455                 460                 


Gln Val Ala Val Pro Ala Thr Asp Thr Thr Asp Lys Met Gln Thr Ser 
465                 470                 475                 480 


Leu Asp Glu Val Met Lys Thr Thr Lys 
                485                 


<210>  868
<211>  541
<212>  PRT
<213>  Homo Sapiens

<400>  868

Ala Gly Gly Gly Gly Val Ala Val Thr Ser Ala Ala Gly Gly Gly Ser 
1               5                   10                  15      


Pro Pro Ala Thr Ser Cys Pro Val Ala Cys Ser Cys Ser Asn Gln Ala 
            20                  25                  30          


Ser Arg Val Ile Cys Thr Arg Arg Asp Leu Ala Glu Val Pro Ala Ser 
        35                  40                  45              


Ile Pro Val Asn Thr Arg Tyr Leu Asn Leu Gln Glu Asn Gly Ile Gln 
    50                  55                  60                  


Val Ile Arg Thr Asp Thr Phe Lys His Leu Arg His Leu Glu Ile Leu 
65                  70                  75                  80  


Gln Leu Ser Lys Asn Leu Val Arg Lys Ile Glu Val Gly Ala Phe Asn 
                85                  90                  95      


Gly Leu Pro Ser Leu Asn Thr Leu Glu Leu Phe Asp Asn Arg Leu Thr 
            100                 105                 110         


Thr Val Pro Thr Gln Ala Phe Glu Tyr Leu Ser Lys Leu Arg Glu Leu 
        115                 120                 125             


Trp Leu Arg Asn Asn Pro Ile Glu Ser Ile Pro Ser Tyr Ala Phe Asn 
    130                 135                 140                 


Arg Val Pro Ser Leu Arg Arg Leu Asp Leu Gly Glu Leu Lys Arg Leu 
145                 150                 155                 160 


Glu Tyr Ile Ser Glu Ala Ala Phe Glu Gly Leu Val Asn Leu Arg Tyr 
                165                 170                 175     


Leu Asn Leu Gly Met Cys Asn Leu Lys Asp Ile Pro Asn Leu Thr Ala 
            180                 185                 190         


Leu Val Arg Leu Glu Glu Leu Glu Leu Ser Gly Asn Arg Leu Asp Leu 
        195                 200                 205             


Ile Arg Pro Gly Ser Phe Gln Gly Leu Thr Ser Leu Arg Lys Leu Trp 
    210                 215                 220                 


Leu Met His Ala Gln Val Ala Thr Ile Glu Arg Asn Ala Phe Asp Asp 
225                 230                 235                 240 


Leu Lys Ser Leu Glu Glu Leu Asn Leu Ser His Asn Asn Leu Met Ser 
                245                 250                 255     


Leu Pro His Asp Leu Phe Thr Pro Leu His Arg Leu Glu Arg Val His 
            260                 265                 270         


Leu Asn His Asn Pro Trp His Cys Asn Cys Asp Val Leu Trp Leu Ser 
        275                 280                 285             


Trp Trp Leu Lys Glu Thr Val Pro Ser Asn Thr Thr Cys Cys Ala Arg 
    290                 295                 300                 


Cys His Ala Pro Ala Gly Leu Lys Gly Arg Tyr Ile Gly Glu Leu Asp 
305                 310                 315                 320 


Gln Ser His Phe Thr Cys Tyr Ala Pro Val Ile Val Glu Pro Pro Thr 
                325                 330                 335     


Asp Leu Asn Val Thr Glu Gly Met Ala Ala Glu Leu Lys Cys Arg Thr 
            340                 345                 350         


Gly Thr Ser Met Thr Ser Val Asn Trp Leu Thr Pro Asn Gly Thr Leu 
        355                 360                 365             


Met Thr His Gly Ser Tyr Arg Val Arg Ile Ser Val Leu His Asp Gly 
    370                 375                 380                 


Thr Leu Asn Phe Thr Asn Val Thr Val Gln Asp Thr Gly Gln Tyr Thr 
385                 390                 395                 400 


Cys Met Val Thr Asn Ser Ala Gly Asn Thr Thr Ala Ser Ala Thr Leu 
                405                 410                 415     


Asn Val Ser Ala Val Asp Pro Val Ala Ala Gly Gly Thr Gly Ser Gly 
            420                 425                 430         


Gly Gly Gly Pro Gly Gly Ser Gly Gly Val Gly Gly Gly Ser Gly Gly 
        435                 440                 445             


Tyr Thr Tyr Phe Thr Thr Val Thr Val Glu Thr Leu Glu Thr Gln Pro 
    450                 455                 460                 


Gly Glu Glu Ala Leu Gln Pro Arg Gly Thr Glu Lys Glu Pro Pro Gly 
465                 470                 475                 480 


Pro Thr Thr Asp Gly Val Trp Gly Gly Gly Arg Pro Gly Asp Ala Ala 
                485                 490                 495     


Gly Pro Ala Ser Ser Ser Thr Thr Ala Pro Ala Pro Arg Ser Ser Arg 
            500                 505                 510         


Pro Thr Glu Lys Ala Phe Thr Val Pro Ile Thr Asp Val Thr Glu Asn 
        515                 520                 525             


Ala Leu Lys Asp Leu Asp Asp Val Met Lys Thr Thr Lys 
    530                 535                 540     


<210>  869
<211>  483
<212>  PRT
<213>  Homo Sapiens

<400>  869

Gln Thr Cys Pro Ser Val Cys Ser Cys Ser Asn Gln Phe Ser Lys Val 
1               5                   10                  15      


Ile Cys Val Arg Lys Asn Leu Arg Glu Val Pro Asp Gly Ile Ser Thr 
            20                  25                  30          


Asn Thr Arg Leu Leu Asn Leu His Glu Asn Gln Ile Gln Ile Ile Lys 
        35                  40                  45              


Val Asn Ser Phe Lys His Leu Arg His Leu Glu Ile Leu Gln Leu Ser 
    50                  55                  60                  


Arg Asn His Ile Arg Thr Ile Glu Ile Gly Ala Phe Asn Gly Leu Ala 
65                  70                  75                  80  


Asn Leu Asn Thr Leu Glu Leu Phe Asp Asn Arg Leu Thr Thr Ile Pro 
                85                  90                  95      


Asn Gly Ala Phe Val Tyr Leu Ser Lys Leu Lys Glu Leu Trp Leu Arg 
            100                 105                 110         


Asn Asn Pro Ile Glu Ser Ile Pro Ser Tyr Ala Phe Asn Arg Ile Pro 
        115                 120                 125             


Ser Leu Arg Arg Leu Asp Leu Gly Glu Leu Lys Arg Leu Ser Tyr Ile 
    130                 135                 140                 


Ser Glu Gly Ala Phe Glu Gly Leu Ser Asn Leu Arg Tyr Leu Asn Leu 
145                 150                 155                 160 


Ala Met Cys Asn Leu Arg Glu Ile Pro Asn Leu Thr Pro Leu Ile Lys 
                165                 170                 175     


Leu Asp Glu Leu Asp Leu Ser Gly Asn His Leu Ser Ala Ile Arg Pro 
            180                 185                 190         


Gly Ser Phe Gln Gly Leu Met His Leu Gln Lys Leu Trp Met Ile Gln 
        195                 200                 205             


Ser Gln Ile Gln Val Ile Glu Arg Asn Ala Phe Asp Asn Leu Gln Ser 
    210                 215                 220                 


Leu Val Glu Ile Asn Leu Ala His Asn Asn Leu Thr Leu Leu Pro His 
225                 230                 235                 240 


Asp Leu Phe Thr Pro Leu His His Leu Glu Arg Ile His Leu His His 
                245                 250                 255     


Asn Pro Trp Asn Cys Asn Cys Asp Ile Leu Trp Leu Ser Trp Trp Ile 
            260                 265                 270         


Lys Asp Met Ala Pro Ser Asn Thr Ala Cys Cys Ala Arg Cys Asn Thr 
        275                 280                 285             


Pro Pro Asn Leu Lys Gly Arg Tyr Ile Gly Glu Leu Asp Gln Asn Tyr 
    290                 295                 300                 


Phe Thr Cys Tyr Ala Pro Val Ile Val Glu Pro Pro Ala Asp Leu Asn 
305                 310                 315                 320 


Val Thr Glu Gly Met Ala Ala Glu Leu Lys Cys Arg Ala Ser Thr Ser 
                325                 330                 335     


Leu Thr Ser Val Ser Trp Ile Thr Pro Asn Gly Thr Val Met Thr His 
            340                 345                 350         


Gly Ala Tyr Lys Val Arg Ile Ala Val Leu Ser Asp Gly Thr Leu Asn 
        355                 360                 365             


Phe Thr Asn Val Thr Val Gln Asp Thr Gly Met Tyr Thr Cys Met Val 
    370                 375                 380                 


Ser Asn Ser Val Gly Asn Thr Thr Ala Ser Ala Thr Leu Asn Val Thr 
385                 390                 395                 400 


Ala Ala Thr Thr Thr Pro Phe Ser Tyr Phe Ser Thr Val Thr Val Glu 
                405                 410                 415     


Thr Met Glu Pro Ser Gln Asp Glu Ala Arg Thr Thr Asp Asn Asn Val 
            420                 425                 430         


Gly Pro Thr Pro Val Val Asp Trp Glu Thr Thr Asn Val Thr Thr Ser 
        435                 440                 445             


Leu Thr Pro Gln Ser Thr Arg Ser Thr Glu Lys Thr Phe Thr Ile Pro 
    450                 455                 460                 


Val Thr Asp Ile Asn Ser Gly Ile Pro Gly Ile Asp Glu Val Met Lys 
465                 470                 475                 480 


Thr Thr Lys 
            


<210>  870
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  870

Ser Lys Cys Pro Asn Asn Cys Leu Cys Gln Ala Gln Glu Val Ile Cys 
1               5                   10                  15      


Thr Gly Lys Gln Leu Thr Glu Tyr Pro Leu Asp Ile Pro Leu Asn Thr 
            20                  25                  30          


Arg Arg Leu Phe Leu Asn Glu Asn Arg Ile Thr Ser Leu Pro Ala Met 
        35                  40                  45              


His Leu Gly Leu Leu Ser Asp Leu Val Tyr Leu Asp Cys Gln Asn Asn 
    50                  55                  60                  


Arg Ile Arg Glu Val Met Asp Tyr Thr Phe Ile Gly Val Phe Lys Leu 
65                  70                  75                  80  


Ile Tyr Leu Asp Leu Ser Ser Asn Asn Leu Thr Ser Ile Ser Pro Phe 
                85                  90                  95      


Thr Phe Ser Val Leu Ser Asn Leu Val Gln Leu Asn Ile Ala Asn Asn 
            100                 105                 110         


Pro His Leu Leu Ser Leu His Lys Phe Thr Phe Ala Asn Thr Thr Ser 
        115                 120                 125             


Leu Arg Tyr Leu Asp Leu Arg Asn Thr Gly Leu Gln Thr Leu Asp Ser 
    130                 135                 140                 


Ala Ala Leu Tyr His Leu Thr Thr Leu Glu Thr Leu Phe Leu Ser Gly 
145                 150                 155                 160 


Asn Pro Trp Lys Cys Asn Cys Ser Phe Leu Asp Phe Ala Ile Phe Leu 
                165                 170                 175     


Ile Val Phe His Met Asp Pro Ser Asp Asp Leu Asn Ala Thr Cys Val 
            180                 185                 190         


Glu Pro Thr Glu Leu Thr Gly Trp Pro Ile Thr Arg Val Gly Asn Pro 
        195                 200                 205             


Leu Arg Tyr Met Cys Ile Thr His Leu Asp His Lys Asp 
    210                 215                 220     


<210>  871
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  871

Gly Thr Ser Cys Pro Val Leu Cys Thr Cys Arg Asn Gln Val Val Asp 
1               5                   10                  15      


Cys Ser Ser Gln Arg Leu Phe Ser Val Pro Pro Asp Leu Pro Met Asp 
            20                  25                  30          


Thr Arg Asn Leu Ser Leu Ala His Asn Arg Ile Thr Ala Val Pro Pro 
        35                  40                  45              


Gly Tyr Leu Thr Cys Tyr Met Glu Leu Gln Val Leu Asp Leu His Asn 
    50                  55                  60                  


Asn Ser Leu Met Glu Leu Pro Arg Gly Leu Phe Leu His Ala Lys Arg 
65                  70                  75                  80  


Leu Ala His Leu Asp Leu Ser Tyr Asn Asn Phe Ser His Val Pro Ala 
                85                  90                  95      


Asp Met Phe Gln Glu Ala His Gly Leu Val His Ile Asp Leu Ser His 
            100                 105                 110         


Asn Pro Trp Leu Arg Arg Val His Pro Gln Ala Phe Gln Gly Leu Met 
        115                 120                 125             


Gln Leu Arg Asp Leu Asp Leu Ser Tyr Gly Gly Leu Ala Phe Leu Ser 
    130                 135                 140                 


Leu Glu Ala Leu Glu Gly Leu Pro Gly Leu Val Thr Leu Gln Ile Gly 
145                 150                 155                 160 


Gly Asn Pro Trp Val Cys Gly Cys Thr Met Glu Pro Leu Leu Lys Trp 
                165                 170                 175     


Leu Arg Asn Arg Ile Gln Arg Cys Thr Ala Asp Ser Gln Leu Ala Glu 
            180                 185                 190         


Cys Arg Gly Pro Pro Glu Val Glu Gly Ala Pro Leu Phe Ser Leu Thr 
        195                 200                 205             


Glu Glu Ser Phe Lys Ala Cys His Leu Thr Leu Thr Leu Asp Asp Tyr 
    210                 215                 220                 


<210>  872
<211>  442
<212>  PRT
<213>  Homo Sapiens

<400>  872

Ser Leu Val Ala Leu Tyr Leu Asp Asn Ser Asn Ile Leu Tyr Val Tyr 
1               5                   10                  15      


Pro Lys Ala Phe Val Gln Leu Arg His Leu Tyr Phe Leu Phe Leu Asn 
            20                  25                  30          


Asn Asn Phe Ile Lys Arg Leu Asp Pro Gly Ile Phe Lys Gly Leu Leu 
        35                  40                  45              


Asn Leu Arg Asn Leu Tyr Leu Gln Tyr Asn Gln Val Ser Phe Val Pro 
    50                  55                  60                  


Arg Gly Val Phe Asn Asp Leu Val Ser Val Gln Tyr Leu Asn Leu Gln 
65                  70                  75                  80  


Arg Asn Arg Leu Thr Val Leu Gly Ser Gly Thr Phe Val Gly Met Val 
                85                  90                  95      


Ala Leu Arg Ile Leu Asp Leu Ser Asn Asn Asn Ile Leu Arg Ile Ser 
            100                 105                 110         


Glu Ser Gly Phe Gln His Leu Glu Asn Leu Ala Cys Leu Tyr Leu Gly 
        115                 120                 125             


Ser Asn Asn Leu Thr Lys Val Pro Ser Asn Ala Phe Glu Val Leu Lys 
    130                 135                 140                 


Ser Leu Arg Arg Leu Ser Leu Ser His Asn Pro Ile Glu Ala Ile Gln 
145                 150                 155                 160 


Pro Phe Ala Phe Lys Gly Leu Ala Asn Leu Glu Tyr Leu Leu Leu Lys 
                165                 170                 175     


Asn Ser Arg Ile Arg Asn Val Thr Arg Asp Gly Phe Ser Gly Ile Asn 
            180                 185                 190         


Asn Leu Lys His Leu Ile Leu Ser His Asn Asp Leu Glu Asn Leu Asn 
        195                 200                 205             


Ser Asp Thr Phe Ser Leu Leu Lys Asn Leu Ile Tyr Leu Lys Leu Asp 
    210                 215                 220                 


Arg Asn Arg Ile Ile Ser Ile Asp Asn Asp Thr Phe Glu Asn Met Gly 
225                 230                 235                 240 


Ala Ser Leu Lys Ile Leu Asn Leu Ser Phe Asn Asn Leu Thr Ala Leu 
                245                 250                 255     


His Pro Arg Val Leu Lys Pro Leu Ser Ser Leu Ile His Leu Gln Ala 
            260                 265                 270         


Asn Ser Asn Pro Trp Glu Cys Asn Cys Lys Leu Leu Gly Leu Arg Asp 
        275                 280                 285             


Trp Leu Ala Ser Ser Ala Ile Thr Leu Asn Ile Tyr Cys Gln Asn Pro 
    290                 295                 300                 


Pro Ser Met Arg Gly Arg Ala Leu Arg Tyr Ile Asn Ile Thr Asn Cys 
305                 310                 315                 320 


Val Thr Ser Ser Ile Asn Val Ser Arg Ala Trp Ala Val Val Lys Ser 
                325                 330                 335     


Pro His Ile His His Lys Thr Thr Ala Leu Met Met Ala Trp His Lys 
            340                 345                 350         


Val Thr Thr Asn Gly Ser Pro Leu Glu Asn Thr Glu Thr Glu Asn Ile 
        355                 360                 365             


Thr Phe Trp Glu Arg Ile Pro Thr Ser Pro Ala Gly Arg Phe Phe Gln 
    370                 375                 380                 


Glu Asn Ala Phe Gly Asn Pro Leu Glu Thr Thr Ala Val Leu Pro Val 
385                 390                 395                 400 


Gln Ile Gln Leu Thr Thr Ser Val Thr Leu Asn Leu Glu Lys Asn Ser 
                405                 410                 415     


Ala Leu Pro Asn Asp Ala Ala Ser Met Ser Gly Lys Thr Ser Leu Ile 
            420                 425                 430         


Cys Thr Gln Glu Val Glu Lys Leu Asn Glu 
        435                 440         


<210>  873
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  873

Gln Val Thr Gln Asp Lys Met Ile Cys Leu Pro Cys Lys Trp Val Thr 
1               5                   10                  15      


Lys Asp Ser Cys Asn Asp Ser Phe Arg Gly Trp Ala Ala Pro Gly Pro 
            20                  25                  30          


Glu Pro Thr Tyr Pro Asn Ser Thr Ile Leu Pro Thr Pro Asp Thr Gly 
        35                  40                  45              


Pro Thr Gly Ile Lys Tyr Asp Leu Asp Arg His Gln Tyr Asn Tyr Val 
    50                  55                  60                  


Asp Ala Val Cys Tyr Glu Asn Arg Leu His Trp Phe Ala Lys 
65                  70                  75              


<210>  874
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  874

Leu Thr Gln Ser Arg Val Leu Cys Cys Leu Pro Cys Lys Val Glu Phe 
1               5                   10                  15      


Asp Asn His Cys Ala Val Pro Trp Asp Ile Leu Lys Ala Ser Met Asn 
            20                  25                  30          


Thr Ser Ser Asn Pro Gly Thr Pro Leu Pro Leu Pro Leu Arg Ile Gln 
        35                  40                  45              


Asn Asp Leu His Arg Gln Gln Tyr Ser Tyr Ile Asp Ala Val Cys Tyr 
    50                  55                  60                  


Glu Lys Gln Leu His Trp Phe Ala Lys 
65                  70              


<210>  875
<211>  82
<212>  PRT
<213>  Homo Sapiens

<400>  875

Thr Leu Gln Val Met Gln Asp Lys Ile Ile Cys Leu Pro Lys Arg Val 
1               5                   10                  15      


Gln Pro Ala Gln Asn His Ser Ser Leu Ser Asn Val Ser Gln Ala Val 
            20                  25                  30          


Ala Ser Thr Thr Pro Leu Pro Pro Pro Lys Pro Ser Pro Ala Asn Pro 
        35                  40                  45              


Ile Thr Val Glu Met Lys Gly Leu Lys Thr Asp Leu Asp Leu Gln Gln 
    50                  55                  60                  


Tyr Ser Phe Ile Asn Gln Met Cys Tyr Glu Arg Ala Leu His Trp Tyr 
65                  70                  75                  80  


Ala Lys 
        


<210>  876
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  876

Thr Met Gln Leu Thr Lys Asp Gln Val Val Cys Leu Pro Val Leu Pro 
1               5                   10                  15      


Ser Pro Val Asn Ser Lys Ala His Thr Pro Pro Gly Asn Ala Glu Val 
            20                  25                  30          


Thr Thr Asn Ile Pro Lys Met Glu Ala Ala Thr Asn Gln Asp Gln Asp 
        35                  40                  45              


Gly Arg Thr Thr Asn Asp Ile Ser Phe Gly Thr Ser Ala Val Thr Pro 
    50                  55                  60                  


Asp Ile Pro Leu Arg Ala Thr Tyr Pro Arg Thr Asp Phe Ala Leu Pro 
65                  70                  75                  80  


Asn Gln Glu Ala Lys Lys Glu Lys Lys Asp Pro Thr Gly Arg Lys Thr 
                85                  90                  95      


Asn Leu Asp Phe Gln Gln Tyr Val Phe Ile Asn Gln Met Cys Tyr His 
            100                 105                 110         


Leu Ala Leu Pro Trp Tyr Ser Lys 
        115                 120 


<210>  877
<211>  606
<212>  PRT
<213>  Homo Sapiens

<400>  877

Ser Ile Gln Asn Ser Glu Cys Pro Gln Leu Cys Val Cys Glu Ile Arg 
1               5                   10                  15      


Pro Trp Phe Thr Pro Gln Ser Thr Tyr Arg Glu Ala Thr Thr Val Asp 
            20                  25                  30          


Cys Asn Asp Leu Arg Leu Thr Arg Ile Pro Ser Asn Leu Ser Ser Asp 
        35                  40                  45              


Thr Gln Val Leu Leu Leu Gln Ser Asn Asn Ile Ala Lys Thr Val Asp 
    50                  55                  60                  


Glu Leu Gln Gln Leu Phe Asn Leu Thr Glu Leu Asp Phe Ser Gln Asn 
65                  70                  75                  80  


Asn Phe Thr Asn Ile Lys Glu Val Gly Leu Ala Asn Leu Thr Gln Leu 
                85                  90                  95      


Thr Thr Leu His Leu Glu Glu Asn Gln Ile Thr Glu Met Thr Asp Tyr 
            100                 105                 110         


Cys Leu Gln Asp Leu Ser Asn Leu Gln Glu Leu Tyr Ile Asn His Asn 
        115                 120                 125             


Gln Ile Ser Thr Ile Ser Ala His Ala Phe Ala Gly Leu Lys Asn Leu 
    130                 135                 140                 


Leu Arg Leu His Leu Asn Ser Asn Lys Leu Lys Val Ile Asp Ser Arg 
145                 150                 155                 160 


Trp Phe Asp Ser Thr Pro Asn Leu Glu Ile Leu Met Ile Gly Glu Asn 
                165                 170                 175     


Pro Val Ile Gly Ile Leu Asp Met Asn Phe Lys Pro Leu Ala Asn Leu 
            180                 185                 190         


Arg Ser Leu Val Leu Ala Gly Met Tyr Leu Thr Asp Ile Pro Gly Asn 
        195                 200                 205             


Ala Leu Val Gly Leu Asp Ser Leu Glu Ser Leu Ser Phe Tyr Asp Asn 
    210                 215                 220                 


Lys Leu Val Lys Val Pro Gln Leu Ala Leu Gln Lys Val Pro Ser Leu 
225                 230                 235                 240 


Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile His Lys Ile Gln Glu Gly 
                245                 250                 255     


Asp Phe Lys Asn Met Leu Arg Leu Lys Glu Leu Gly Ile Asn Asn Met 
            260                 265                 270         


Gly Glu Leu Val Ser Val Asp Arg Tyr Ala Leu Asp Asn Leu Pro Glu 
        275                 280                 285             


Leu Thr Lys Leu Glu Ala Thr Asn Asn Pro Lys Leu Ser Tyr Ile His 
    290                 295                 300                 


Arg Leu Ala Phe Arg Ser Val Pro Ala Leu Glu Ser Leu Met Leu Asn 
305                 310                 315                 320 


Asn Asn Ala Leu Asn Ala Ile Tyr Gln Lys Thr Val Glu Ser Leu Pro 
                325                 330                 335     


Asn Leu Arg Glu Ile Ser Ile His Ser Asn Pro Leu Arg Cys Asp Cys 
            340                 345                 350         


Val Ile His Trp Ile Asn Ser Asn Lys Thr Asn Ile Arg Phe Met Glu 
        355                 360                 365             


Pro Leu Ser Met Phe Cys Ala Met Pro Pro Glu Tyr Lys Gly His Gln 
    370                 375                 380                 


Val Lys Glu Val Leu Ile Gln Asp Ser Ser Glu Gln Cys Leu Pro Met 
385                 390                 395                 400 


Ile Ser His Asp Ser Phe Pro Asn Arg Leu Asn Val Asp Ile Gly Thr 
                405                 410                 415     


Thr Val Phe Leu Asp Cys Arg Ala Met Ala Glu Pro Glu Pro Glu Ile 
            420                 425                 430         


Tyr Trp Val Thr Pro Ile Gly Asn Lys Ile Thr Val Glu Thr Leu Ser 
        435                 440                 445             


Asp Lys Tyr Lys Leu Ser Ser Glu Gly Thr Leu Glu Ile Ser Asn Ile 
    450                 455                 460                 


Gln Ile Glu Asp Ser Gly Arg Tyr Thr Cys Val Ala Gln Asn Val Gln 
465                 470                 475                 480 


Gly Ala Asp Thr Arg Val Ala Thr Ile Lys Val Asn Gly Thr Leu Leu 
                485                 490                 495     


Asp Gly Thr Gln Val Leu Lys Ile Tyr Val Lys Gln Thr Glu Ser His 
            500                 505                 510         


Ser Ile Leu Val Ser Trp Lys Val Asn Ser Asn Val Met Thr Ser Asn 
        515                 520                 525             


Leu Lys Trp Ser Ser Ala Thr Met Lys Ile Asp Asn Pro His Ile Thr 
    530                 535                 540                 


Tyr Thr Ala Arg Val Pro Val Asp Val His Glu Tyr Asn Leu Thr His 
545                 550                 555                 560 


Leu Gln Pro Ser Thr Asp Tyr Glu Val Cys Leu Thr Val Ser Asn Ile 
                565                 570                 575     


His Gln Gln Thr Gln Lys Ser Cys Val Asn Val Thr Thr Lys Asn Ala 
            580                 585                 590         


Ala Phe Ala Val Asp Ile Ser Asp Gln Glu Thr Ser Thr Ala 
        595                 600                 605     


<210>  878
<211>  606
<212>  PRT
<213>  Homo Sapiens

<400>  878

Val Asp Lys Lys Val Asp Cys Pro Arg Leu Cys Thr Cys Glu Ile Arg 
1               5                   10                  15      


Pro Trp Phe Thr Pro Arg Ser Ile Tyr Met Glu Ala Ser Thr Val Asp 
            20                  25                  30          


Cys Asn Asp Leu Gly Leu Leu Thr Phe Pro Ala Arg Leu Pro Ala Asn 
        35                  40                  45              


Thr Gln Ile Leu Leu Leu Gln Thr Asn Asn Ile Ala Lys Ile Glu Tyr 
    50                  55                  60                  


Ser Thr Asp Phe Pro Val Asn Leu Thr Ser Leu Asp Leu Ser Gln Asn 
65                  70                  75                  80  


Asn Leu Ser Ser Val Thr Asn Ile Asn Val Lys Lys Met Pro Gln Leu 
                85                  90                  95      


Leu Ser Val Tyr Leu Glu Glu Asn Lys Leu Thr Glu Leu Pro Glu Lys 
            100                 105                 110         


Cys Leu Ser Glu Leu Ser Asn Leu Gln Glu Leu Tyr Ile Asn His Asn 
        115                 120                 125             


Leu Leu Ser Thr Ile Ser Pro Gly Ala Phe Ile Gly Leu His Asn Leu 
    130                 135                 140                 


Leu Arg Leu His Leu Asn Ser Asn Arg Leu Gln Met Ile Asn Ser Lys 
145                 150                 155                 160 


Trp Phe Asp Ala Leu Pro Asn Leu Glu Ile Leu Met Ile Gly Glu Asn 
                165                 170                 175     


Pro Ile Ile Arg Ile Lys Asp Met Asn Phe Lys Pro Leu Ile Asn Leu 
            180                 185                 190         


Arg Ser Leu Val Ile Ala Gly Ile Asn Leu Thr Glu Ile Pro Asp Asn 
        195                 200                 205             


Ala Leu Val Gly Leu Glu Asn Leu Glu Ser Ile Ser Phe Tyr Asp Asn 
    210                 215                 220                 


Arg Leu Ile Lys Val Pro His Val Ala Leu Gln Lys Val Val Asn Leu 
225                 230                 235                 240 


Lys Phe Leu Asp Leu Asn Lys Asn Pro Ile Asn Arg Ile Arg Arg Gly 
                245                 250                 255     


Asp Phe Ser Asn Met Leu His Leu Lys Glu Leu Gly Ile Asn Asn Met 
            260                 265                 270         


Pro Glu Leu Ile Ser Ile Asp Ser Leu Ala Val Asp Asn Leu Pro Asp 
        275                 280                 285             


Leu Arg Lys Ile Glu Ala Thr Asn Asn Pro Arg Leu Ser Tyr Ile His 
    290                 295                 300                 


Pro Asn Ala Phe Phe Arg Leu Pro Lys Leu Glu Ser Leu Met Leu Asn 
305                 310                 315                 320 


Ser Asn Ala Leu Ser Ala Leu Tyr His Gly Thr Ile Glu Ser Leu Pro 
                325                 330                 335     


Asn Leu Lys Glu Ile Ser Ile His Ser Asn Pro Ile Arg Cys Asp Cys 
            340                 345                 350         


Val Ile Arg Trp Met Asn Met Asn Lys Thr Asn Ile Arg Phe Met Glu 
        355                 360                 365             


Pro Asp Ser Leu Phe Cys Val Asp Pro Pro Glu Phe Gln Gly Gln Asn 
    370                 375                 380                 


Val Arg Gln Val His Phe Arg Asp Met Met Glu Ile Cys Leu Pro Leu 
385                 390                 395                 400 


Ile Ala Pro Glu Ser Phe Pro Ser Asn Leu Asn Val Glu Ala Gly Ser 
                405                 410                 415     


Tyr Val Ser Phe His Cys Arg Ala Thr Ala Glu Pro Gln Pro Glu Ile 
            420                 425                 430         


Tyr Trp Ile Thr Pro Ser Gly Gln Lys Leu Leu Pro Asn Thr Leu Thr 
        435                 440                 445             


Asp Lys Phe Tyr Val His Ser Glu Gly Thr Leu Asp Ile Asn Gly Val 
    450                 455                 460                 


Thr Pro Lys Glu Gly Gly Leu Tyr Thr Cys Ile Ala Thr Asn Leu Val 
465                 470                 475                 480 


Gly Ala Asp Leu Lys Ser Val Met Ile Lys Val Asp Gly Ser Phe Pro 
                485                 490                 495     


Gln Asp Asn Asn Gly Ser Leu Asn Ile Lys Ile Arg Asp Ile His Ala 
            500                 505                 510         


Asn Ser Val Leu Val Ser Trp Lys Ala Ser Ser Lys Ile Leu Lys Ser 
        515                 520                 525             


Ser Val Lys Trp Thr Ala Phe Val Lys Thr Glu Asn Ser His Ala Ala 
    530                 535                 540                 


Gln Ser Ala Arg Ile Pro Ser Asp Val Lys Val Tyr Asn Leu Thr His 
545                 550                 555                 560 


Leu Asn Pro Ser Thr Glu Tyr Lys Ile Cys Ile Asp Ile Pro Thr Ile 
                565                 570                 575     


Tyr Gln Lys Asn Arg Lys Lys Cys Val Asn Val Thr Thr Lys Gly Leu 
            580                 585                 590         


His Pro Asp Gln Lys Glu Tyr Glu Lys Asn Asn Thr Thr Thr 
        595                 600                 605     


<210>  879
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  879

Asp Pro Pro Gln Glu Lys Val Pro Leu Phe Arg Val Thr Gln Gln Gly 
1               5                   10                  15      


Pro Trp Gly Ser Ser Gly Ser Asn Ala Thr Asp Ser Pro Cys Glu Gly 
            20                  25                  30          


Leu Pro Ala Ala Asp Ala Thr Ala Leu Thr Leu Ala Asn Arg Asn Leu 
        35                  40                  45              


Glu Arg Leu Pro Gly Cys Leu Pro Arg Thr Leu Arg Ser Leu Asp Ala 
    50                  55                  60                  


Ser His Asn Leu Leu Arg Ala Leu Ser Thr Ser Glu Leu Gly His Leu 
65                  70                  75                  80  


Glu Gln Leu Gln Val Leu Thr Leu Arg His Asn Arg Ile Ala Ala Leu 
                85                  90                  95      


Arg Trp Gly Pro Gly Gly Pro Ala Gly Leu His Thr Leu Asp Leu Ser 
            100                 105                 110         


Tyr Asn Gln Leu Ala Ala Leu Leu Pro Cys Thr Gly Pro Ala Leu Ser 
        115                 120                 125             


Ser Leu Arg Ala Leu Ala Leu Ala Gly Asn Pro Leu Arg Ala Leu Gln 
    130                 135                 140                 


Pro Arg Ala Phe Ala Cys Phe Pro Ala Leu Gln Leu Leu Asn Leu Ser 
145                 150                 155                 160 


Cys Thr Ala Leu Gly Arg Gly Ala Gln Gly Gly Ile Ala Glu Ala Ala 
                165                 170                 175     


Phe Ala Gly Glu Asp Gly Ala Pro Leu Val Thr Leu Glu Val Leu Asp 
            180                 185                 190         


Leu Ser Gly Thr Phe Leu Glu Arg Val Glu Ser Gly Trp Ile Arg Asp 
        195                 200                 205             


Leu Pro Lys Leu Thr Ser Leu Tyr Leu Arg Lys Met Pro Arg Leu Thr 
    210                 215                 220                 


Thr Leu Glu Gly Asp Ile Phe Lys Met Thr Pro Asn Leu Gln Gln Leu 
225                 230                 235                 240 


Asp Cys Gln Asp Ser Pro Ala Leu Ala Ser Val Ala Thr His Ile Phe 
                245                 250                 255     


Gln Asp Thr Pro His Leu Gln Val Leu Leu Phe Gln Asn Cys Asn Leu 
            260                 265                 270         


Ser Ser Phe Pro Pro Trp Thr Leu Asp Ser Ser Gln Val Leu Ser Ile 
        275                 280                 285             


Asn Leu Phe Gly Asn Pro Leu Thr Cys Ser Cys Asp Leu Ser Trp Leu 
    290                 295                 300                 


Leu Thr Asp Ala Lys Arg Thr Val Leu Ser Arg Ala Ala Asp Thr Met 
305                 310                 315                 320 


Cys Ala Pro Ala Ala Gly Ser Ser Gly Pro Phe Ser Ala Ser Leu Ser 
                325                 330                 335     


Leu Ser Gln Leu Pro Gly Val Cys Gln Ser Asp Gln Ser Thr Thr Leu 
            340                 345                 350         


Gly Ala Ser His Pro Pro Cys Phe Asn Arg Ser Thr Tyr Ala Gln Gly 
        355                 360                 365             


Thr Thr Val Ala Pro Ser Ala Ala Pro Ala Thr Arg Pro Ala Gly Asp 
    370                 375                 380                 


Gln Gln Ser Val Ser Lys Ala Pro Asn Val Gly Ser Arg Thr Ile Ala 
385                 390                 395                 400 


Ala Trp Pro His Ser Asp Ala Arg Glu Gly Thr Ala Pro Ser Thr Thr 
                405                 410                 415     


Asn Ser Val Ala Gly His Ser Asn Ser Ser Val Phe Pro Arg Ala Ala 
            420                 425                 430         


Ser Thr Thr Arg Thr Gln His Arg Gly Glu His Ala Pro Glu Leu Val 
        435                 440                 445             


Leu Glu Pro Asp Ile Ser Ala Ala Ser Thr Pro Leu Ala Ser Lys Leu 
    450                 455                 460                 


Leu Gly Pro Phe Pro Thr Ser Trp Asp Arg Ser Ile Ser Ser Pro Gln 
465                 470                 475                 480 


Pro Gly Gln Arg Thr His Ala Thr Pro Gln Ala Pro Asn Pro Ser Leu 
                485                 490                 495     


Ser Glu Gly Glu Ile Pro Val Leu Leu Leu Asp Asp Tyr Ser Glu Glu 
            500                 505                 510         


Glu Glu Gly Arg Lys Glu Glu Val Gly Thr Pro His Gln Asp Val Pro 
        515                 520                 525             


Cys Asp Tyr His Pro Cys Lys His Leu Gln Thr Pro Cys Ala Glu Leu 
    530                 535                 540                 


Gln Arg Arg Trp Arg Cys Arg Cys Pro Gly Leu Ser Gly Glu Asp Thr 
545                 550                 555                 560 


Ile Pro Asp Pro Pro Arg Leu Gln Gly Val Thr Glu Thr Thr Asp Thr 
                565                 570                 575     


Ser Ala Leu Val His Trp Cys Ala Pro Asn Ser Val Val His Gly Tyr 
            580                 585                 590         


Gln Ile Arg Tyr Ser Ala Glu Gly Trp Ala Gly Asn Gln Ser Val Val 
        595                 600                 605             


Gly Val Ile Tyr Ala Thr Ala Arg Gln His Pro Leu Tyr Gly Leu Ser 
    610                 615                 620                 


Pro Gly Thr Thr Tyr Arg Val Cys Val Leu Ala Ala Asn Arg Ala Gly 
625                 630                 635                 640 


Leu Ser Gln Pro Arg Ser Ser Gly Trp Arg Ser Pro Cys Ala Ala Phe 
                645                 650                 655     


Thr Thr Lys Pro Ser 
            660     


<210>  880
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  880

Leu Ala Pro Gln Asp Phe Glu Glu Glu Glu Ala Asp Glu Thr Glu Thr 
1               5                   10                  15      


Ala Trp Pro Pro Leu Pro Ala Val Pro Cys Asp Tyr Asp His Cys Arg 
            20                  25                  30          


His Leu Gln Val Pro Cys Lys Glu Leu Gln Arg Val Gly Pro Ala Ala 
        35                  40                  45              


Cys Leu Cys Pro Gly Leu Ser Ser Pro Ala Gln Pro Pro Asp Pro Pro 
    50                  55                  60                  


Arg Met Gly Glu Val Arg Ile Ala Ala Glu Glu Gly Arg Ala Val Val 
65                  70                  75                  80  


His Trp Cys Ala Pro Phe Ser Pro Val Leu His Tyr Trp Leu Leu Leu 
                85                  90                  95      


Trp Asp Gly Ser Glu Ala Ala Gln Lys Gly Pro Pro Leu Asn Ala Thr 
            100                 105                 110         


Val Arg Arg Ala Glu Leu Lys Gly Leu Lys Pro Gly Gly Ile Tyr Val 
        115                 120                 125             


Val Cys Val Val Ala Ala Asn Glu Ala Gly Ala Ser Arg Val Pro Gln 
    130                 135                 140                 


Ala Gly Gly Glu Gly Leu Glu Gly Ala Asp Ile Pro Ala Phe Gly Pro 
145                 150                 155                 160 


Cys Ser Arg Leu Ala Val Pro Pro Asn Pro Arg Thr 
                165                 170         


<210>  881
<211>  612
<212>  PRT
<213>  Homo Sapiens

<400>  881

Ala Val Pro Val Val Pro Trp His Val Pro Cys Pro Pro Gln Cys Ala 
1               5                   10                  15      


Cys Gln Ile Arg Pro Trp Tyr Thr Pro Arg Ser Ser Tyr Arg Glu Ala 
            20                  25                  30          


Thr Thr Val Asp Cys Asn Asp Leu Phe Leu Thr Ala Val Pro Pro Ala 
        35                  40                  45              


Leu Pro Ala Gly Thr Gln Thr Leu Leu Leu Gln Ser Asn Ser Ile Val 
    50                  55                  60                  


Arg Val Asp Gln Ser Glu Leu Gly Tyr Leu Ala Asn Leu Thr Glu Leu 
65                  70                  75                  80  


Asp Leu Ser Gln Asn Ser Phe Ser Asp Ala Arg Asp Cys Asp Phe His 
                85                  90                  95      


Ala Leu Pro Gln Leu Leu Ser Leu His Leu Glu Glu Asn Gln Leu Thr 
            100                 105                 110         


Arg Leu Glu Asp His Ser Phe Ala Gly Leu Ala Ser Leu Gln Glu Leu 
        115                 120                 125             


Tyr Leu Asn His Asn Gln Leu Tyr Arg Ile Ala Pro Arg Ala Phe Ser 
    130                 135                 140                 


Gly Leu Ser Asn Leu Leu Arg Leu His Leu Asn Ser Asn Leu Leu Arg 
145                 150                 155                 160 


Ala Ile Asp Ser Arg Trp Phe Glu Met Leu Pro Asn Leu Glu Ile Leu 
                165                 170                 175     


Met Ile Gly Gly Asn Lys Val Asp Ala Ile Leu Asp Met Asn Phe Arg 
            180                 185                 190         


Pro Leu Ala Asn Leu Arg Ser Leu Val Leu Ala Gly Met Asn Leu Arg 
        195                 200                 205             


Glu Ile Ser Asp Tyr Ala Leu Glu Gly Leu Gln Ser Leu Glu Ser Leu 
    210                 215                 220                 


Ser Phe Tyr Asp Asn Gln Leu Ala Arg Val Pro Arg Arg Ala Leu Glu 
225                 230                 235                 240 


Gln Val Pro Gly Leu Lys Phe Leu Asp Leu Asn Lys Asn Pro Leu Gln 
                245                 250                 255     


Arg Val Gly Pro Gly Asp Phe Ala Asn Met Leu His Leu Lys Glu Leu 
            260                 265                 270         


Gly Leu Asn Asn Met Glu Glu Leu Val Ser Ile Asp Lys Phe Ala Leu 
        275                 280                 285             


Val Asn Leu Pro Glu Leu Thr Lys Leu Asp Ile Thr Asn Asn Pro Arg 
    290                 295                 300                 


Leu Ser Phe Ile His Pro Arg Ala Phe His His Leu Pro Gln Met Glu 
305                 310                 315                 320 


Thr Leu Met Leu Asn Asn Asn Ala Leu Ser Ala Leu His Gln Gln Thr 
                325                 330                 335     


Ala Glu Ser Leu Pro Asn Leu Gln Glu Val Gly Leu His Gly Asn Pro 
            340                 345                 350         


Ile Arg Cys Asp Cys Val Ile Arg Trp Ala Asn Ala Thr Gly Thr Arg 
        355                 360                 365             


Val Arg Phe Ile Glu Pro Gln Ser Thr Leu Cys Ala Glu Pro Pro Asp 
    370                 375                 380                 


Leu Gln Arg Leu Pro Val Arg Glu Val Pro Phe Arg Glu Met Thr Asp 
385                 390                 395                 400 


His Cys Leu Pro Leu Ile Ser Pro Arg Ser Phe Pro Pro Ser Leu Gln 
                405                 410                 415     


Val Ala Ser Gly Glu Ser Met Val Leu His Cys Arg Ala Leu Ala Glu 
            420                 425                 430         


Pro Glu Pro Glu Ile Tyr Trp Val Thr Pro Ala Gly Leu Arg Leu Thr 
        435                 440                 445             


Pro Ala His Ala Gly Arg Arg Tyr Arg Val Tyr Pro Glu Gly Thr Leu 
    450                 455                 460                 


Glu Leu Arg Arg Val Thr Ala Glu Glu Ala Gly Leu Tyr Thr Cys Val 
465                 470                 475                 480 


Ala Gln Asn Leu Val Gly Ala Asp Thr Lys Thr Val Ser Val Val Val 
                485                 490                 495     


Gly Arg Ala Leu Leu Gln Pro Gly Arg Asp Glu Gly Gln Gly Leu Glu 
            500                 505                 510         


Leu Arg Val Gln Glu Thr His Pro Tyr His Ile Leu Leu Ser Trp Val 
        515                 520                 525             


Thr Pro Pro Asn Thr Val Ser Thr Asn Leu Thr Trp Ser Ser Ala Ser 
    530                 535                 540                 


Ser Leu Arg Gly Gln Gly Ala Thr Ala Leu Ala Arg Leu Pro Arg Gly 
545                 550                 555                 560 


Thr His Ser Tyr Asn Ile Thr Arg Leu Leu Gln Ala Thr Glu Tyr Trp 
                565                 570                 575     


Ala Cys Leu Gln Val Ala Phe Ala Asp Ala His Thr Gln Leu Ala Cys 
            580                 585                 590         


Val Trp Ala Arg Thr Lys Glu Ala Thr Ser Cys His Arg Ala Leu Gly 
        595                 600                 605             


Asp Arg Pro Gly 
    610         


<210>  882
<211>  393
<212>  PRT
<213>  Homo Sapiens

<400>  882

Ala Pro Ser Gly Cys Pro Gln Leu Cys Arg Cys Glu Gly Arg Leu Leu 
1               5                   10                  15      


Tyr Cys Glu Ala Leu Asn Leu Thr Glu Ala Pro His Asn Leu Ser Gly 
            20                  25                  30          


Leu Leu Gly Leu Ser Leu Arg Tyr Asn Ser Leu Ser Glu Leu Arg Ala 
        35                  40                  45              


Gly Gln Phe Thr Gly Leu Met Gln Leu Thr Trp Leu Tyr Leu Asp His 
    50                  55                  60                  


Asn His Ile Cys Ser Val Gln Gly Asp Ala Phe Gln Lys Leu Arg Arg 
65                  70                  75                  80  


Val Lys Glu Leu Thr Leu Ser Ser Asn Gln Ile Thr Gln Leu Pro Asn 
                85                  90                  95      


Thr Thr Phe Arg Pro Met Pro Asn Leu Arg Ser Val Asp Leu Ser Tyr 
            100                 105                 110         


Asn Lys Leu Gln Ala Leu Ala Pro Asp Leu Phe His Gly Leu Arg Lys 
        115                 120                 125             


Leu Thr Thr Leu His Met Arg Ala Asn Ala Ile Gln Phe Val Pro Val 
    130                 135                 140                 


Arg Ile Phe Gln Asp Cys Arg Ser Leu Lys Phe Leu Asp Ile Gly Tyr 
145                 150                 155                 160 


Asn Gln Leu Lys Ser Leu Ala Arg Asn Ser Phe Ala Gly Leu Phe Lys 
                165                 170                 175     


Leu Thr Glu Leu His Leu Glu His Asn Asp Leu Val Lys Val Asn Phe 
            180                 185                 190         


Ala His Phe Pro Arg Leu Ile Ser Leu His Ser Leu Cys Leu Arg Arg 
        195                 200                 205             


Asn Lys Val Ala Ile Val Val Ser Ser Leu Asp Trp Val Trp Asn Leu 
    210                 215                 220                 


Glu Lys Met Asp Leu Ser Gly Asn Glu Ile Glu Tyr Met Glu Pro His 
225                 230                 235                 240 


Val Phe Glu Thr Val Pro His Leu Gln Ser Leu Gln Leu Asp Ser Asn 
                245                 250                 255     


Arg Leu Thr Tyr Ile Glu Pro Arg Ile Leu Asn Ser Trp Lys Ser Leu 
            260                 265                 270         


Thr Ser Ile Thr Leu Ala Gly Asn Leu Trp Asp Cys Gly Arg Asn Val 
        275                 280                 285             


Cys Ala Leu Ala Ser Trp Leu Ser Asn Phe Gln Gly Arg Tyr Asp Gly 
    290                 295                 300                 


Asn Leu Gln Cys Ala Ser Pro Glu Tyr Ala Gln Gly Glu Asp Val Leu 
305                 310                 315                 320 


Asp Ala Val Tyr Ala Phe His Leu Cys Glu Asp Gly Ala Glu Pro Thr 
                325                 330                 335     


Ser Gly His Leu Leu Ser Ala Val Thr Asn Arg Ser Asp Leu Gly Pro 
            340                 345                 350         


Pro Ala Ser Ser Ala Thr Thr Leu Ala Asp Gly Gly Glu Gly Gln His 
        355                 360                 365             


Asp Gly Thr Phe Glu Pro Ala Thr Val Ala Leu Pro Gly Gly Glu His 
    370                 375                 380                 


Ala Glu Asn Ala Val Gln Ile His Lys 
385                 390             


<210>  883
<211>  389
<212>  PRT
<213>  Homo Sapiens

<400>  883

Cys Pro Pro Lys Cys Arg Cys Glu Lys Leu Leu Phe Tyr Cys Asp Ser 
1               5                   10                  15      


Gln Gly Phe His Ser Val Pro Asn Ala Thr Asp Lys Gly Ser Leu Gly 
            20                  25                  30          


Leu Ser Leu Arg His Asn His Ile Thr Glu Leu Glu Arg Asp Gln Phe 
        35                  40                  45              


Ala Ser Phe Ser Gln Leu Thr Trp Leu His Leu Asp His Asn Gln Ile 
    50                  55                  60                  


Ser Thr Val Lys Glu Asp Ala Phe Gln Gly Leu Tyr Lys Leu Lys Glu 
65                  70                  75                  80  


Leu Ile Leu Ser Ser Asn Lys Ile Phe Tyr Leu Pro Asn Thr Thr Phe 
                85                  90                  95      


Thr Gln Leu Ile Asn Leu Gln Asn Leu Asp Leu Ser Phe Asn Gln Leu 
            100                 105                 110         


Ser Ser Leu His Pro Glu Leu Phe Tyr Gly Leu Arg Lys Leu Gln Thr 
        115                 120                 125             


Leu His Leu Arg Ser Asn Ser Leu Arg Thr Ile Pro Val Arg Leu Phe 
    130                 135                 140                 


Trp Asp Cys Arg Ser Leu Glu Phe Leu Asp Leu Ser Thr Asn Arg Leu 
145                 150                 155                 160 


Arg Ser Leu Ala Arg Asn Gly Phe Ala Gly Leu Ile Lys Leu Arg Glu 
                165                 170                 175     


Leu His Leu Glu His Asn Gln Leu Thr Lys Ile Asn Phe Ala His Phe 
            180                 185                 190         


Leu Arg Leu Ser Ser Leu His Thr Leu Phe Leu Gln Trp Asn Lys Ile 
        195                 200                 205             


Ser Asn Leu Thr Cys Gly Met Glu Trp Thr Trp Gly Thr Leu Glu Lys 
    210                 215                 220                 


Leu Asp Leu Thr Gly Asn Glu Ile Lys Ala Ile Asp Leu Thr Val Phe 
225                 230                 235                 240 


Glu Thr Met Pro Asn Leu Lys Ile Leu Leu Met Asp Asn Asn Lys Leu 
                245                 250                 255     


Asn Ser Leu Asp Ser Lys Ile Leu Asn Ser Leu Arg Ser Leu Thr Thr 
            260                 265                 270         


Val Gly Leu Ser Gly Asn Leu Trp Glu Cys Ser Ala Arg Ile Cys Ala 
        275                 280                 285             


Leu Ala Ser Trp Leu Gly Ser Phe Gln Gly Arg Trp Glu His Ser Ile 
    290                 295                 300                 


Leu Cys His Ser Pro Asp His Thr Gln Gly Glu Asp Ile Leu Asp Ala 
305                 310                 315                 320 


Val His Gly Phe Gln Leu Cys Trp Asn Leu Ser Thr Thr Val Thr Val 
                325                 330                 335     


Met Ala Thr Thr Tyr Arg Asp Pro Thr Thr Glu Tyr Thr Lys Arg Ile 
            340                 345                 350         


Ser Ser Ser Ser Tyr His Val Gly Asp Lys Glu Ile Pro Thr Thr Ala 
        355                 360                 365             


Gly Ile Ala Val Thr Thr Glu Glu His Phe Pro Glu Pro Asp Asn Ala 
    370                 375                 380                 


Ile Phe Thr Gln Arg 
385                 


<210>  884
<211>  389
<212>  PRT
<213>  Homo Sapiens

<400>  884

Glu Arg Gly Cys Pro Lys Gly Cys Arg Cys Glu Gly Lys Met Val Tyr 
1               5                   10                  15      


Cys Glu Ser Gln Lys Leu Gln Glu Ile Pro Ser Ser Ile Ser Ala Gly 
            20                  25                  30          


Cys Leu Gly Leu Ser Leu Arg Tyr Asn Ser Leu Gln Lys Leu Lys Tyr 
        35                  40                  45              


Asn Gln Phe Lys Gly Leu Asn Gln Leu Thr Trp Leu Tyr Leu Asp His 
    50                  55                  60                  


Asn His Ile Ser Asn Ile Asp Glu Asn Ala Phe Asn Gly Ile Arg Arg 
65                  70                  75                  80  


Leu Lys Glu Leu Ile Leu Ser Ser Asn Arg Ile Ser Tyr Phe Leu Asn 
                85                  90                  95      


Asn Thr Phe Arg Pro Val Thr Asn Leu Arg Asn Leu Asp Leu Ser Tyr 
            100                 105                 110         


Asn Gln Leu His Ser Leu Gly Ser Glu Gln Phe Arg Gly Leu Arg Lys 
        115                 120                 125             


Leu Leu Ser Leu His Leu Arg Ser Asn Ser Leu Arg Thr Ile Pro Val 
    130                 135                 140                 


Arg Ile Phe Gln Asp Cys Arg Asn Leu Glu Leu Leu Asp Leu Gly Tyr 
145                 150                 155                 160 


Asn Arg Ile Arg Ser Leu Ala Arg Asn Val Phe Ala Gly Met Ile Arg 
                165                 170                 175     


Leu Lys Glu Leu His Leu Glu His Asn Gln Phe Ser Lys Leu Asn Leu 
            180                 185                 190         


Ala Leu Phe Pro Arg Leu Val Ser Leu Gln Asn Leu Tyr Leu Gln Trp 
        195                 200                 205             


Asn Lys Ile Ser Val Ile Gly Gln Thr Met Ser Trp Thr Trp Ser Ser 
    210                 215                 220                 


Leu Gln Arg Leu Asp Leu Ser Gly Asn Glu Ile Glu Ala Phe Ser Gly 
225                 230                 235                 240 


Pro Ser Val Phe Gln Cys Val Pro Asn Leu Gln Arg Leu Asn Leu Asp 
                245                 250                 255     


Ser Asn Lys Leu Thr Phe Ile Gly Gln Glu Ile Leu Asp Ser Trp Ile 
            260                 265                 270         


Ser Leu Asn Asp Ile Ser Leu Ala Gly Asn Ile Trp Glu Cys Ser Arg 
        275                 280                 285             


Asn Ile Cys Ser Leu Val Asn Trp Leu Lys Ser Phe Lys Gly Leu Arg 
    290                 295                 300                 


Glu Asn Thr Ile Ile Cys Ala Ser Pro Lys Glu Leu Gln Gly Val Asn 
305                 310                 315                 320 


Val Ile Asp Ala Val Lys Asn Tyr Ser Ile Cys Gly Lys Ser Thr Thr 
                325                 330                 335     


Glu Arg Phe Asp Leu Ala Arg Ala Leu Pro Lys Pro Thr Phe Lys Pro 
            340                 345                 350         


Lys Leu Pro Arg Pro Lys His Glu Ser Lys Pro Pro Leu Pro Pro Thr 
        355                 360                 365             


Val Gly Ala Thr Glu Pro Gly Pro Glu Thr Asp Ala Asp Ala Glu His 
    370                 375                 380                 


Ile Ser Phe His Lys 
385                 


<210>  885
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  885

Gln Arg Ala Cys Pro Lys Asn Cys Arg Cys Asp Gly Lys Ile Val Tyr 
1               5                   10                  15      


Cys Glu Ser His Ala Phe Ala Asp Ile Pro Glu Asn Ile Ser Gly Gly 
            20                  25                  30          


Ser Gln Gly Leu Ser Leu Arg Phe Asn Ser Ile Gln Lys Leu Lys Ser 
        35                  40                  45              


Asn Gln Phe Ala Gly Leu Asn Gln Leu Ile Trp Leu Tyr Leu Asp His 
    50                  55                  60                  


Asn Tyr Ile Ser Ser Val Asp Glu Asp Ala Phe Gln Gly Ile Arg Arg 
65                  70                  75                  80  


Leu Lys Glu Leu Ile Leu Ser Ser Asn Lys Ile Thr Tyr Leu His Asn 
                85                  90                  95      


Lys Thr Phe His Pro Val Pro Asn Leu Arg Asn Leu Asp Leu Ser Tyr 
            100                 105                 110         


Asn Lys Leu Gln Thr Leu Gln Ser Glu Gln Phe Lys Gly Leu Arg Lys 
        115                 120                 125             


Leu Ile Ile Leu His Leu Arg Ser Asn Ser Leu Lys Thr Val Pro Ile 
    130                 135                 140                 


Arg Val Phe Gln Asp Cys Arg Asn Leu Asp Phe Leu Asp Leu Gly Tyr 
145                 150                 155                 160 


Asn Arg Leu Arg Ser Leu Ser Arg Asn Ala Phe Ala Gly Leu Leu Lys 
                165                 170                 175     


Leu Lys Glu Leu His Leu Glu His Asn Gln Phe Ser Lys Ile Asn Phe 
            180                 185                 190         


Ala His Phe Pro Arg Leu Phe Asn Leu Arg Ser Ile Tyr Leu Gln Trp 
        195                 200                 205             


Asn Arg Ile Arg Ser Ile Ser Gln Gly Leu Thr Trp Thr Trp Ser Ser 
    210                 215                 220                 


Leu His Asn Leu Asp Leu Ser Gly Asn Asp Ile Gln Gly Ile Glu Pro 
225                 230                 235                 240 


Gly Thr Phe Lys Cys Leu Pro Asn Leu Gln Lys Leu Asn Leu Asp Ser 
                245                 250                 255     


Asn Lys Leu Thr Asn Ile Ser Gln Glu Thr Val Asn Ala Trp Ile Ser 
            260                 265                 270         


Leu Ile Ser Ile Thr Leu Ser Gly Asn Met Trp Glu Cys Ser Arg Ser 
        275                 280                 285             


Ile Cys Pro Leu Phe Tyr Trp Leu Lys Asn Phe Lys Gly Asn Lys Glu 
    290                 295                 300                 


Ser Thr Met Ile Cys Ala Gly Pro Lys His Ile Gln Gly Glu Lys Val 
305                 310                 315                 320 


Ser Asp Ala Val Glu Thr Tyr Asn Ile Cys Ser Glu Val Gln Val Val 
                325                 330                 335     


Asn Thr Glu Arg Ser His Leu Val Pro Gln Thr Pro Gln Lys Pro Leu 
            340                 345                 350         


Ile Ile Pro Arg Pro Thr Ile Phe Lys Pro Asp Val Thr Gln Ser Thr 
        355                 360                 365             


Phe Glu Thr Pro Ser Pro Ser Pro Gly Phe Gln Ile Pro Gly Ala Glu 
    370                 375                 380                 


Gln Glu Tyr Glu His Val Ser Phe His Lys 
385                 390                 


<210>  886
<211>  261
<212>  PRT
<213>  Homo Sapiens

<400>  886

Gln Ser Ser Thr Asn Phe Val Asp Cys Ser Gln Gln Gly Leu Ala Glu 
1               5                   10                  15      


Ile Pro Ser His Leu Pro Pro Gln Thr Arg Thr Leu His Leu Gln Asp 
            20                  25                  30          


Asn Gln Ile His His Leu Pro Ala Phe Ala Phe Arg Ser Val Pro Trp 
        35                  40                  45              


Leu Met Thr Leu Asn Leu Ser Asn Asn Ser Leu Ser Asn Leu Ala Pro 
    50                  55                  60                  


Gly Ala Phe His Gly Leu Gln His Leu Gln Val Leu Asn Leu Thr Gln 
65                  70                  75                  80  


Asn Ser Leu Leu Ser Leu Glu Ser Arg Leu Phe His Ser Leu Pro Gln 
                85                  90                  95      


Leu Arg Glu Leu Asp Leu Ser Ser Asn Asn Ile Ser His Leu Pro Thr 
            100                 105                 110         


Ser Leu Gly Glu Thr Trp Glu Asn Leu Thr Ile Leu Ala Val Gln Gln 
        115                 120                 125             


Asn Gln Leu Gln Gln Leu Asp Arg Ala Leu Leu Glu Ser Met Pro Ser 
    130                 135                 140                 


Val Arg Leu Leu Leu Leu Lys Asp Asn Leu Trp Lys Cys Asn Cys His 
145                 150                 155                 160 


Leu Leu Gly Leu Lys Leu Trp Leu Glu Lys Phe Val Tyr Lys Gly Gly 
                165                 170                 175     


Leu Thr Asp Gly Ile Ile Cys Glu Ser Pro Asp Thr Trp Lys Gly Lys 
            180                 185                 190         


Asp Leu Leu Arg Ile Pro His Glu Leu Tyr Gln Pro Cys Pro Leu Pro 
        195                 200                 205             


Ala Pro Asp Pro Val Ser Ser Gln Ala Gln Trp Pro Gly Ser Ala His 
    210                 215                 220                 


Gly Val Val Leu Arg Pro Pro Glu Asn His Asn Ala Gly Glu Arg Glu 
225                 230                 235                 240 


Leu Leu Glu Cys Glu Leu Lys Pro Lys Pro Arg Pro Ala Asn Leu Arg 
                245                 250                 255     


His Ala Ile Ala Thr 
            260     


<210>  887
<211>  275
<212>  PRT
<213>  Homo Sapiens

<400>  887

Leu Pro Thr Cys Pro Phe Ser Cys Lys Cys Asp Ser Arg Ser Leu Glu 
1               5                   10                  15      


Val Asp Cys Ser Gly Leu Gly Leu Thr Thr Val Pro Pro Asp Val Pro 
            20                  25                  30          


Ala Ala Thr Arg Thr Leu Leu Leu Leu Asn Asn Lys Leu Ser Ala Leu 
        35                  40                  45              


Pro Ser Trp Ala Phe Ala Asn Leu Ser Ser Leu Gln Arg Leu Asp Leu 
    50                  55                  60                  


Ser Asn Asn Phe Leu Asp Arg Leu Pro Arg Ser Ile Phe Gly Asp Leu 
65                  70                  75                  80  


Thr Asn Leu Thr Glu Leu Gln Leu Arg Asn Asn Ser Ile Arg Thr Leu 
                85                  90                  95      


Asp Arg Asp Leu Leu Arg His Ser Pro Leu Leu Arg His Leu Asp Leu 
            100                 105                 110         


Ser Ile Asn Gly Leu Ala Gln Leu Pro Pro Gly Leu Phe Asp Gly Leu 
        115                 120                 125             


Leu Ala Leu Arg Ser Leu Ser Leu Arg Ser Asn Arg Leu Gln Asn Leu 
    130                 135                 140                 


Asp Arg Leu Thr Phe Glu Pro Leu Ala Asn Leu Gln Leu Leu Gln Val 
145                 150                 155                 160 


Gly Asp Asn Pro Trp Glu Cys Asp Cys Asn Leu Arg Glu Phe Lys His 
                165                 170                 175     


Trp Met Glu Trp Phe Ser Tyr Arg Gly Gly Arg Leu Asp Gln Leu Ala 
            180                 185                 190         


Cys Thr Leu Pro Lys Glu Leu Arg Gly Lys Asp Met Arg Met Val Pro 
        195                 200                 205             


Met Glu Met Phe Asn Tyr Cys Ser Gln Leu Glu Asp Glu Asn Ser Ser 
    210                 215                 220                 


Ala Gly Leu Asp Ile Pro Gly Pro Pro Cys Thr Lys Ala Ser Pro Glu 
225                 230                 235                 240 


Pro Ala Lys Pro Lys Pro Gly Ala Glu Pro Glu Pro Glu Pro Ser Thr 
                245                 250                 255     


Ala Cys Pro Gln Lys Gln Arg His Arg Pro Ala Ser Val Arg Arg Ala 
            260                 265                 270         


Met Gly Thr 
        275 


<210>  888
<211>  287
<212>  PRT
<213>  Homo Sapiens

<400>  888

Val Arg Ser Val Asp Phe Asn Arg Gly Thr Asp Asn Ile Thr Val Arg 
1               5                   10                  15      


Gln Gly Asp Thr Ala Ile Leu Arg Cys Val Val Glu Asp Lys Asn Ser 
            20                  25                  30          


Lys Val Ala Trp Leu Asn Arg Ser Gly Ile Ile Phe Ala Gly His Asp 
        35                  40                  45              


Lys Trp Ser Leu Asp Pro Arg Val Glu Leu Glu Lys Arg His Ser Leu 
    50                  55                  60                  


Glu Tyr Ser Leu Arg Ile Gln Lys Val Asp Val Tyr Asp Glu Gly Ser 
65                  70                  75                  80  


Tyr Thr Cys Ser Val Gln Thr Gln His Glu Pro Lys Thr Ser Gln Val 
                85                  90                  95      


Tyr Leu Ile Val Gln Val Pro Pro Lys Ile Ser Asn Ile Ser Ser Asp 
            100                 105                 110         


Val Thr Val Asn Glu Gly Ser Asn Val Thr Leu Val Cys Met Ala Asn 
        115                 120                 125             


Gly Arg Pro Glu Pro Val Ile Thr Trp Arg His Leu Thr Pro Thr Gly 
    130                 135                 140                 


Arg Glu Phe Glu Gly Glu Glu Glu Tyr Leu Glu Ile Leu Gly Ile Thr 
145                 150                 155                 160 


Arg Glu Gln Ser Gly Lys Tyr Glu Cys Lys Ala Ala Asn Glu Val Ser 
                165                 170                 175     


Ser Ala Asp Val Lys Gln Val Lys Val Thr Val Asn Tyr Pro Pro Thr 
            180                 185                 190         


Ile Thr Glu Ser Lys Ser Asn Glu Ala Thr Thr Gly Arg Gln Ala Ser 
        195                 200                 205             


Leu Lys Cys Glu Ala Ser Ala Val Pro Ala Pro Asp Phe Glu Trp Tyr 
    210                 215                 220                 


Arg Asp Asp Thr Arg Ile Asn Ser Ala Asn Gly Leu Glu Ile Lys Ser 
225                 230                 235                 240 


Thr Glu Gly Gln Ser Ser Leu Thr Val Thr Asn Val Thr Glu Glu His 
                245                 250                 255     


Tyr Gly Asn Tyr Thr Cys Val Ala Ala Asn Lys Leu Gly Val Thr Asn 
            260                 265                 270         


Ala Ser Leu Val Leu Phe Arg Pro Gly Ser Val Arg Gly Ile Asn 
        275                 280                 285         


<210>  889
<211>  259
<212>  PRT
<213>  Homo Sapiens

<400>  889

Met Gln Gln Asp Gly Leu Gly Val Gly Thr Arg Asn Gly Ser Gly Lys 
1               5                   10                  15      


Gly Arg Ser Val His Pro Ser Trp Pro Trp Cys Ala Pro Arg Pro Leu 
            20                  25                  30          


Arg Tyr Phe Gly Arg Asp Ala Arg Ala Arg Arg Ala Gln Thr Ala Ala 
        35                  40                  45              


Met Ala Leu Leu Ala Gly Gly Leu Ser Arg Gly Leu Gly Ser His Pro 
    50                  55                  60                  


Ala Ala Ala Gly Arg Asp Ala Val Val Phe Val Trp Leu Leu Leu Ser 
65                  70                  75                  80  


Thr Trp Cys Thr Ala Pro Ala Arg Ala Ile Gln Val Thr Val Ser Asn 
                85                  90                  95      


Pro Tyr His Val Val Ile Leu Phe Gln Pro Val Thr Leu Pro Cys Thr 
            100                 105                 110         


Tyr Gln Met Thr Ser Thr Pro Thr Gln Pro Ile Val Ile Trp Lys Tyr 
        115                 120                 125             


Lys Ser Phe Cys Arg Asp Arg Ile Ala Asp Ala Phe Ser Pro Ala Ser 
    130                 135                 140                 


Val Asp Asn Gln Leu Asn Ala Gln Leu Ala Ala Gly Asn Pro Gly Tyr 
145                 150                 155                 160 


Asn Pro Tyr Val Glu Cys Gln Asp Ser Val Arg Thr Val Arg Val Val 
                165                 170                 175     


Ala Thr Lys Gln Gly Asn Ala Val Thr Leu Gly Asp Tyr Tyr Gln Gly 
            180                 185                 190         


Arg Arg Ile Thr Ile Thr Gly Asn Ala Asp Leu Thr Phe Asp Gln Thr 
        195                 200                 205             


Ala Trp Gly Asp Ser Gly Val Tyr Tyr Cys Ser Val Val Ser Ala Gln 
    210                 215                 220                 


Asp Leu Gln Gly Asn Asn Glu Ala Tyr Ala Glu Leu Ile Val Leu Gly 
225                 230                 235                 240 


Arg Thr Ser Gly Val Ala Glu Leu Leu Pro Gly Phe Gln Ala Gly Pro 
                245                 250                 255     


Ile Glu Asp 
            


<210>  890
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  890

Leu Pro Gly Val Gly Leu Thr Pro Ser Ala Ala Gln Thr Ala Arg Gln 
1               5                   10                  15      


His Pro Lys Met His Leu Ala His Ser Thr Leu Lys Pro Ala Ala His 
            20                  25                  30          


Leu Ile Gly Asp Pro Ser Lys Gln Asn Ser Leu Leu Trp Arg Ala Asn 
        35                  40                  45              


Thr Asp Arg Ala Phe Leu Gln Asp Gly Phe Ser Leu Ser Asn Asn Ser 
    50                  55                  60                  


Leu Leu Val Pro Thr Ser Gly Ile Tyr Phe Val Tyr Ser Gln Val Val 
65                  70                  75                  80  


Phe Ser Gly Lys Ala Tyr Ser Pro Lys Ala Thr Ser Ser Pro Leu Tyr 
                85                  90                  95      


Leu Ala His Glu Val Gln Leu Phe Ser Ser Gln Tyr Pro Phe His Val 
            100                 105                 110         


Pro Leu Leu Ser Ser Gln Lys Met Val Tyr Pro Gly Leu Gln Glu Pro 
        115                 120                 125             


Trp Leu His Ser Met Tyr His Gly Ala Ala Phe Gln Leu Thr Gln Gly 
    130                 135                 140                 


Asp Gln Leu Ser Thr His Thr Asp Gly Ile Pro His Leu Val Leu Ser 
145                 150                 155                 160 


Pro Ser Thr Val Phe Phe Gly Ala Phe Ala Leu 
                165                 170     


<210>  891
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  891

Gln Asp Gln Gly Gly Leu Val Thr Glu Thr Ala Asp Pro Gly Ala Gln 
1               5                   10                  15      


Ala Gln Gln Gly Leu Gly Phe Gln Lys Leu Pro Glu Glu Glu Pro Glu 
            20                  25                  30          


Thr Asp Leu Ser Pro Gly Leu Pro Ala Ala His Leu Ile Gly Ala Pro 
        35                  40                  45              


Leu Lys Gly Gln Gly Leu Gly Trp Glu Thr Thr Lys Glu Gln Ala Phe 
    50                  55                  60                  


Leu Thr Ser Gly Thr Gln Phe Ser Asp Ala Glu Gly Leu Ala Leu Pro 
65                  70                  75                  80  


Gln Asp Gly Leu Tyr Tyr Leu Tyr Cys Leu Val Gly Tyr Arg Gly Arg 
                85                  90                  95      


Ala Pro Pro Gly Gly Gly Asp Pro Gln Gly Arg Ser Val Thr Leu Arg 
            100                 105                 110         


Ser Ser Leu Tyr Arg Ala Gly Gly Ala Tyr Gly Pro Gly Thr Pro Glu 
        115                 120                 125             


Leu Leu Leu Glu Gly Ala Glu Thr Val Thr Pro Val Leu Asp Pro Ala 
    130                 135                 140                 


Arg Arg Gln Gly Tyr Gly Pro Leu Trp Tyr Thr Ser Val Gly Phe Gly 
145                 150                 155                 160 


Gly Leu Val Gln Leu Arg Arg Gly Glu Arg Val Tyr Val Asn Ile Ser 
                165                 170                 175     


His Pro Asp Met Val Asp Phe Ala Arg Gly Lys Thr Phe Phe Gly Ala 
            180                 185                 190         


Val Met Val Gly 
        195     


<210>  892
<211>  1375
<212>  PRT
<213>  Homo Sapiens

<400>  892

Asn His Thr Gly Arg Ile Lys Val Val Phe Thr Pro Ser Ile Cys Lys 
1               5                   10                  15      


Val Thr Cys Thr Lys Gly Ser Cys Gln Asn Ser Cys Glu Lys Gly Asn 
            20                  25                  30          


Thr Thr Thr Leu Ile Ser Glu Asn Gly His Ala Ala Asp Thr Leu Thr 
        35                  40                  45              


Ala Thr Asn Phe Arg Val Val Ile Cys His Leu Pro Cys Met Asn Gly 
    50                  55                  60                  


Gly Gln Cys Ser Ser Arg Asp Lys Cys Gln Cys Pro Pro Asn Phe Thr 
65                  70                  75                  80  


Gly Lys Leu Cys Gln Ile Pro Val His Gly Ala Ser Val Pro Lys Leu 
                85                  90                  95      


Tyr Gln His Ser Gln Gln Pro Gly Lys Ala Leu Gly Thr His Val Ile 
            100                 105                 110         


His Ser Thr His Thr Leu Pro Leu Thr Val Thr Ser Gln Gln Gly Val 
        115                 120                 125             


Lys Val Lys Phe Pro Pro Asn Ile Val Asn Ile His Val Lys His Pro 
    130                 135                 140                 


Pro Glu Ala Ser Val Gln Ile His Gln Val Ser Arg Ile Asp Gly Pro 
145                 150                 155                 160 


Thr Gly Gln Lys Thr Lys Glu Ala Gln Pro Gly Gln Ser Gln Val Ser 
                165                 170                 175     


Tyr Gln Gly Leu Pro Val Gln Lys Thr Gln Thr Ile His Ser Thr Tyr 
            180                 185                 190         


Ser His Gln Gln Val Ile Pro His Val Tyr Pro Val Ala Ala Lys Thr 
        195                 200                 205             


Gln Leu Gly Arg Cys Phe Gln Glu Thr Ile Gly Ser Gln Cys Gly Lys 
    210                 215                 220                 


Ala Leu Pro Gly Leu Ser Lys Gln Glu Asp Cys Cys Gly Thr Val Gly 
225                 230                 235                 240 


Thr Ser Trp Gly Phe Asn Lys Cys Gln Lys Cys Pro Lys Lys Pro Ser 
                245                 250                 255     


Tyr His Gly Tyr Asn Gln Met Met Glu Cys Leu Pro Gly Tyr Lys Arg 
            260                 265                 270         


Val Asn Asn Thr Phe Cys Gln Asp Ile Asn Glu Cys Gln Leu Gln Gly 
        275                 280                 285             


Val Cys Pro Asn Gly Glu Cys Leu Asn Thr Met Gly Ser Tyr Arg Cys 
    290                 295                 300                 


Thr Cys Lys Ile Gly Phe Gly Pro Asp Pro Thr Phe Ser Ser Cys Val 
305                 310                 315                 320 


Pro Asp Pro Pro Val Ile Ser Glu Glu Lys Gly Pro Cys Tyr Arg Leu 
                325                 330                 335     


Val Ser Ser Gly Arg Gln Cys Met His Pro Leu Ser Val His Leu Thr 
            340                 345                 350         


Lys Gln Leu Cys Cys Cys Ser Val Gly Lys Ala Trp Gly Pro His Cys 
        355                 360                 365             


Glu Lys Cys Pro Leu Pro Gly Thr Ala Ala Phe Lys Glu Ile Cys Pro 
    370                 375                 380                 


Gly Gly Met Gly Tyr Thr Val Ser Gly Val His Arg Arg Arg Pro Ile 
385                 390                 395                 400 


His His His Val Gly Lys Gly Pro Val Phe Val Lys Pro Lys Asn Thr 
                405                 410                 415     


Gln Pro Val Ala Lys Ser Thr His Pro Pro Pro Leu Pro Ala Lys Glu 
            420                 425                 430         


Glu Pro Val Glu Ala Leu Thr Phe Ser Arg Glu His Gly Pro Gly Val 
        435                 440                 445             


Ala Glu Pro Glu Val Ala Thr Ala Pro Pro Glu Lys Glu Ile Pro Ser 
    450                 455                 460                 


Leu Asp Gln Glu Lys Thr Lys Leu Glu Pro Gly Gln Pro Gln Leu Ser 
465                 470                 475                 480 


Pro Gly Ile Ser Thr Ile His Leu His Pro Gln Phe Pro Val Val Ile 
                485                 490                 495     


Glu Lys Thr Ser Pro Pro Val Pro Val Glu Val Ala Pro Glu Ala Ser 
            500                 505                 510         


Thr Ser Ser Ala Ser Gln Val Ile Ala Pro Thr Gln Val Thr Glu Ile 
        515                 520                 525             


Asn Glu Cys Thr Val Asn Pro Asp Ile Cys Gly Ala Gly His Cys Ile 
    530                 535                 540                 


Asn Leu Pro Val Arg Tyr Thr Cys Ile Cys Tyr Glu Gly Tyr Arg Phe 
545                 550                 555                 560 


Ser Glu Gln Gln Arg Lys Cys Val Asp Ile Asp Glu Cys Thr Gln Val 
                565                 570                 575     


Gln His Leu Cys Ser Gln Gly Arg Cys Glu Asn Thr Glu Gly Ser Phe 
            580                 585                 590         


Leu Cys Ile Cys Pro Ala Gly Phe Met Ala Ser Glu Glu Gly Thr Asn 
        595                 600                 605             


Cys Ile Asp Val Asp Glu Cys Leu Arg Pro Asp Val Cys Gly Glu Gly 
    610                 615                 620                 


His Cys Val Asn Thr Val Gly Ala Phe Arg Cys Glu Tyr Cys Asp Ser 
625                 630                 635                 640 


Gly Tyr Arg Met Thr Gln Arg Gly Arg Cys Glu Asp Ile Asp Glu Cys 
                645                 650                 655     


Leu Asn Pro Ser Thr Cys Pro Asp Glu Gln Cys Val Asn Ser Pro Gly 
            660                 665                 670         


Ser Tyr Gln Cys Val Pro Cys Thr Glu Gly Phe Arg Gly Trp Asn Gly 
        675                 680                 685             


Gln Cys Leu Asp Val Asp Glu Cys Leu Glu Pro Asn Val Cys Ala Asn 
    690                 695                 700                 


Gly Asp Cys Ser Asn Leu Glu Gly Ser Tyr Met Cys Ser Cys His Lys 
705                 710                 715                 720 


Gly Tyr Thr Arg Thr Pro Asp His Lys His Cys Arg Asp Ile Asp Glu 
                725                 730                 735     


Cys Gln Gln Gly Asn Leu Cys Val Asn Gly Gln Cys Lys Asn Thr Glu 
            740                 745                 750         


Gly Ser Phe Arg Cys Thr Cys Gly Gln Gly Tyr Gln Leu Ser Ala Ala 
        755                 760                 765             


Lys Asp Gln Cys Glu Asp Ile Asp Glu Cys Gln His Arg His Leu Cys 
    770                 775                 780                 


Ala His Gly Gln Cys Arg Asn Thr Glu Gly Ser Phe Gln Cys Val Cys 
785                 790                 795                 800 


Asp Gln Gly Tyr Arg Ala Ser Gly Leu Gly Asp His Cys Glu Asp Ile 
                805                 810                 815     


Asn Glu Cys Leu Glu Asp Lys Ser Val Cys Gln Arg Gly Asp Cys Ile 
            820                 825                 830         


Asn Thr Ala Gly Ser Tyr Asp Cys Thr Cys Pro Asp Gly Phe Gln Leu 
        835                 840                 845             


Asp Asp Asn Lys Thr Cys Gln Asp Ile Asn Glu Cys Glu His Pro Gly 
    850                 855                 860                 


Leu Cys Gly Pro Gln Gly Glu Cys Leu Asn Thr Glu Gly Ser Phe His 
865                 870                 875                 880 


Cys Val Cys Gln Gln Gly Phe Ser Ile Ser Ala Asp Gly Arg Thr Cys 
                885                 890                 895     


Glu Asp Ile Asp Glu Cys Val Asn Asn Thr Val Cys Asp Ser His Gly 
            900                 905                 910         


Phe Cys Asp Asn Thr Ala Gly Ser Phe Arg Cys Leu Cys Tyr Gln Gly 
        915                 920                 925             


Phe Gln Ala Pro Gln Asp Gly Gln Gly Cys Val Asp Val Asn Glu Cys 
    930                 935                 940                 


Glu Leu Leu Ser Gly Val Cys Gly Glu Ala Phe Cys Glu Asn Val Glu 
945                 950                 955                 960 


Gly Ser Phe Leu Cys Val Cys Ala Asp Glu Asn Gln Glu Tyr Ser Pro 
                965                 970                 975     


Met Thr Gly Gln Cys Arg Ser Arg Thr Ser Thr Asp Leu Asp Val Asp 
            980                 985                 990         


Val Asp Gln Pro Lys Glu Glu Lys  Lys Glu Cys Tyr Tyr  Asn Leu Asn 
        995                 1000                 1005             


Asp Ala  Ser Leu Cys Asp Asn  Val Leu Ala Pro Asn  Val Thr Lys 
    1010                 1015                 1020             


Gln Glu  Cys Cys Cys Thr Ser  Gly Ala Gly Trp Gly  Asp Asn Cys 
    1025                 1030                 1035             


Glu Ile  Phe Pro Cys Pro Val  Leu Gly Thr Ala Glu  Phe Thr Glu 
    1040                 1045                 1050             


Met Cys  Pro Lys Gly Lys Gly  Phe Val Pro Ala Gly  Glu Ser Ser 
    1055                 1060                 1065             


Ser Glu  Ala Gly Gly Glu Asn  Tyr Lys Asp Ala Asp  Glu Cys Leu 
    1070                 1075                 1080             


Leu Phe  Gly Gln Glu Ile Cys  Lys Asn Gly Phe Cys  Leu Asn Thr 
    1085                 1090                 1095             


Arg Pro  Gly Tyr Glu Cys Tyr  Cys Lys Gln Gly Thr  Tyr Tyr Asp 
    1100                 1105                 1110             


Pro Val  Lys Leu Gln Cys Phe  Asp Met Asp Glu Cys  Gln Asp Pro 
    1115                 1120                 1125             


Ser Ser  Cys Ile Asp Gly Gln  Cys Val Asn Thr Glu  Gly Ser Tyr 
    1130                 1135                 1140             


Asn Cys  Phe Cys Thr His Pro  Met Val Leu Asp Ala  Ser Glu Lys 
    1145                 1150                 1155             


Arg Cys  Ile Arg Pro Ala Glu  Ser Asn Glu Gln Ile  Glu Glu Thr 
    1160                 1165                 1170             


Asp Val  Tyr Gln Asp Leu Cys  Trp Glu His Leu Ser  Asp Glu Tyr 
    1175                 1180                 1185             


Val Cys  Ser Arg Pro Leu Val  Gly Lys Gln Thr Thr  Tyr Thr Glu 
    1190                 1195                 1200             


Cys Cys  Cys Leu Tyr Gly Glu  Ala Trp Gly Met Gln  Cys Ala Leu 
    1205                 1210                 1215             


Cys Pro  Leu Lys Asp Ser Asp  Asp Tyr Ala Gln Leu  Cys Asn Ile 
    1220                 1225                 1230             


Pro Val  Thr Gly Arg Arg Gln  Pro Tyr Gly Arg Asp  Ala Leu Val 
    1235                 1240                 1245             


Asp Phe  Ser Glu Gln Tyr Thr  Pro Glu Ala Asp Pro  Tyr Phe Ile 
    1250                 1255                 1260             


Gln Asp  Arg Phe Leu Asn Ser  Phe Glu Glu Leu Gln  Ala Glu Glu 
    1265                 1270                 1275             


Cys Gly  Ile Leu Asn Gly Cys  Glu Asn Gly Arg Cys  Val Arg Val 
    1280                 1285                 1290             


Gln Glu  Gly Tyr Thr Cys Asp  Cys Phe Asp Gly Tyr  His Leu Asp 
    1295                 1300                 1305             


Thr Ala  Lys Met Thr Cys Val  Asp Val Asn Glu Cys  Asp Glu Leu 
    1310                 1315                 1320             


Asn Asn  Arg Met Ser Leu Cys  Lys Asn Ala Lys Cys  Ile Asn Thr 
    1325                 1330                 1335             


Asp Gly  Ser Tyr Lys Cys Leu  Cys Leu Pro Gly Tyr  Val Pro Ser 
    1340                 1345                 1350             


Asp Lys  Pro Asn Tyr Cys Thr  Pro Leu Asn Thr Ala  Leu Asn Leu 
    1355                 1360                 1365             


Glu Lys  Asp Ser Asp Leu Glu  
    1370                 1375 


<210>  893
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  893

Gln Ala Val Pro Pro Tyr Ala Ser Glu Asn Gln Thr Cys Arg Asp Gln 
1               5                   10                  15      


Glu Lys Glu Tyr Tyr Glu Pro Gln His Arg Ile Cys Cys Ser Arg Cys 
            20                  25                  30          


Pro Pro Gly Thr Tyr Val Ser Ala Lys Cys Ser Arg Ile Arg Asp Thr 
        35                  40                  45              


Val Cys Ala Thr Cys Ala Glu Asn Ser Tyr Asn Glu His Trp Asn Tyr 
    50                  55                  60                  


Leu Thr Ile Cys Gln Leu Cys Arg Pro Cys Asp Pro Val Met Gly Leu 
65                  70                  75                  80  


Glu Glu Ile Ala Pro Cys Thr Ser Lys Arg Lys Thr Gln Cys Arg Cys 
                85                  90                  95      


Gln Pro Gly Met Phe Cys Ala Ala Trp Ala Leu Glu Cys Thr His Cys 
            100                 105                 110         


Glu Leu Leu Ser Asp Cys Pro Pro Gly Thr Glu Ala Glu Leu Lys Asp 
        115                 120                 125             


Glu Val Gly Lys Gly Asn Asn His Cys Val Pro Cys Lys Ala Gly His 
    130                 135                 140                 


Phe Gln Asn Thr Ser Ser Pro Ser Ala Arg Cys Gln Pro His Thr Arg 
145                 150                 155                 160 


Cys Glu Asn Gln Gly Leu Val Glu Ala Ala Pro Gly Thr Ala Gln Ser 
                165                 170                 175     


Asp Thr Thr Cys Lys Asn Pro Leu Glu Pro Leu Pro Pro Glu Met Ser 
            180                 185                 190         


Gly Thr Met Leu Met 
        195         


<210>  894
<211>  692
<212>  PRT
<213>  Homo Sapiens

<400>  894

Gly Arg Arg Arg Arg Ser Val Gln Trp Cys Ala Val Ser Gln Pro Glu 
1               5                   10                  15      


Ala Thr Lys Cys Phe Gln Trp Gln Arg Asn Met Arg Lys Val Arg Gly 
            20                  25                  30          


Pro Pro Val Ser Cys Ile Lys Arg Asp Ser Pro Ile Gln Cys Ile Gln 
        35                  40                  45              


Ala Ile Ala Glu Asn Arg Ala Asp Ala Val Thr Leu Asp Gly Gly Phe 
    50                  55                  60                  


Ile Tyr Glu Ala Gly Leu Ala Pro Tyr Lys Leu Arg Pro Val Ala Ala 
65                  70                  75                  80  


Glu Val Tyr Gly Thr Glu Arg Gln Pro Arg Thr His Tyr Tyr Ala Val 
                85                  90                  95      


Ala Val Val Lys Lys Gly Gly Ser Phe Gln Leu Asn Glu Leu Gln Gly 
            100                 105                 110         


Leu Lys Ser Cys His Thr Gly Leu Arg Arg Thr Ala Gly Trp Asn Val 
        115                 120                 125             


Pro Ile Gly Thr Leu Arg Pro Phe Leu Asn Trp Thr Gly Pro Pro Glu 
    130                 135                 140                 


Pro Ile Glu Ala Ala Val Ala Arg Phe Phe Ser Ala Ser Cys Val Pro 
145                 150                 155                 160 


Gly Ala Asp Lys Gly Gln Phe Pro Asn Leu Cys Arg Leu Cys Ala Gly 
                165                 170                 175     


Thr Gly Glu Asn Lys Cys Ala Phe Ser Ser Gln Glu Pro Tyr Phe Ser 
            180                 185                 190         


Tyr Ser Gly Ala Phe Lys Cys Leu Arg Asp Gly Ala Gly Asp Val Ala 
        195                 200                 205             


Phe Ile Arg Glu Ser Thr Val Phe Glu Asp Leu Ser Asp Glu Ala Glu 
    210                 215                 220                 


Arg Asp Glu Tyr Glu Leu Leu Cys Pro Asp Asn Thr Arg Lys Pro Val 
225                 230                 235                 240 


Asp Lys Phe Lys Asp Cys His Leu Ala Arg Val Pro Ser His Ala Val 
                245                 250                 255     


Val Ala Arg Ser Val Asn Gly Lys Glu Asp Ala Ile Trp Asn Leu Leu 
            260                 265                 270         


Arg Gln Ala Gln Glu Lys Phe Gly Lys Asp Lys Ser Pro Lys Phe Gln 
        275                 280                 285             


Leu Phe Gly Ser Pro Ser Gly Gln Lys Asp Leu Leu Phe Lys Asp Ser 
    290                 295                 300                 


Ala Ile Gly Phe Ser Arg Val Pro Pro Arg Ile Asp Ser Gly Leu Tyr 
305                 310                 315                 320 


Leu Gly Ser Gly Tyr Phe Thr Ala Ile Gln Asn Leu Arg Lys Ser Glu 
                325                 330                 335     


Glu Glu Val Ala Ala Arg Arg Ala Arg Val Val Trp Cys Ala Val Gly 
            340                 345                 350         


Glu Gln Glu Leu Arg Lys Cys Asn Gln Trp Ser Gly Leu Ser Glu Gly 
        355                 360                 365             


Ser Val Thr Cys Ser Ser Ala Ser Thr Thr Glu Asp Cys Ile Ala Leu 
    370                 375                 380                 


Val Leu Lys Gly Glu Ala Asp Ala Met Ser Leu Asp Gly Gly Tyr Val 
385                 390                 395                 400 


Tyr Thr Ala Gly Lys Cys Gly Leu Val Pro Val Leu Ala Glu Asn Tyr 
                405                 410                 415     


Lys Ser Gln Gln Ser Ser Asp Pro Asp Pro Asn Cys Val Asp Arg Pro 
            420                 425                 430         


Val Glu Gly Tyr Leu Ala Val Ala Val Val Arg Arg Ser Asp Thr Ser 
        435                 440                 445             


Leu Thr Trp Asn Ser Val Lys Gly Lys Lys Ser Cys His Thr Ala Val 
    450                 455                 460                 


Asp Arg Thr Ala Gly Trp Asn Ile Pro Met Gly Leu Leu Phe Asn Gln 
465                 470                 475                 480 


Thr Gly Ser Cys Lys Phe Asp Glu Tyr Phe Ser Gln Ser Cys Ala Pro 
                485                 490                 495     


Gly Ser Asp Pro Arg Ser Asn Leu Cys Ala Leu Cys Ile Gly Asp Glu 
            500                 505                 510         


Gln Gly Glu Asn Lys Cys Glu Pro Asn Ser Asn Glu Arg Tyr Tyr Gly 
        515                 520                 525             


Tyr Thr Gly Ala Phe Arg Cys Leu Ala Glu Asn Ala Gly Asp Val Ala 
    530                 535                 540                 


Phe Val Lys Asp Val Thr Val Leu Gln Asn Thr Asp Gly Asn Asn Asn 
545                 550                 555                 560 


Glu Ala Trp Ala Lys Asp Leu Lys Leu Ala Asp Phe Ala Leu Leu Cys 
                565                 570                 575     


Leu Asp Gly Lys Arg Lys Pro Val Thr Glu Ala Arg Ser Cys His Leu 
            580                 585                 590         


Ala Met Ala Pro Asn His Ala Val Val Ser Arg Met Asp Lys Val Glu 
        595                 600                 605             


Arg Leu Lys Gln Val Leu Leu His Gln Gln Ala Lys Phe Gly Arg Asn 
    610                 615                 620                 


Gly Ser Asp Cys Pro Asp Lys Phe Cys Leu Phe Gln Ser Glu Thr Lys 
625                 630                 635                 640 


Asn Leu Leu Phe Asn Asp Asn Thr Glu Cys Leu Ala Arg Leu His Gly 
                645                 650                 655     


Lys Thr Thr Tyr Glu Lys Tyr Leu Gly Pro Gln Tyr Val Ala Gly Ile 
            660                 665                 670         


Thr Asn Leu Lys Lys Cys Ser Thr Ser Pro Leu Leu Glu Ala Cys Glu 
        675                 680                 685             


Phe Leu Arg Lys 
    690         


<210>  895
<211>  408
<212>  PRT
<213>  Homo Sapiens

<400>  895

Ile Leu Cys Ser Ser Pro Gly Ser Gln Glu Thr Phe Leu Arg Ser Ser 
1               5                   10                  15      


Pro Leu Pro Leu Ala Ser Pro Ser Pro Arg Asp Pro Lys Val Ser Ala 
            20                  25                  30          


Pro Pro Ser Ile Leu Glu Pro Ala Ser Pro Leu Asn Ser Pro Gly Thr 
        35                  40                  45              


Glu Gly Ser Trp Leu Phe Ser Thr Cys Gly Ala Ser Gly Arg His Gly 
    50                  55                  60                  


Pro Thr Gln Thr Gln Cys Asp Gly Ala Tyr Ala Gly Thr Ser Val Val 
65                  70                  75                  80  


Val Thr Val Gly Ala Ala Gly Gln Leu Arg Gly Val Gln Leu Trp Arg 
                85                  90                  95      


Val Pro Gly Pro Gly Gln Tyr Leu Ile Ser Ala Tyr Gly Ala Ala Gly 
            100                 105                 110         


Gly Lys Gly Ala Lys Asn His Leu Ser Arg Ala His Gly Val Phe Val 
        115                 120                 125             


Ser Ala Ile Phe Ser Leu Gly Leu Gly Glu Ser Leu Tyr Ile Leu Val 
    130                 135                 140                 


Gly Gln Gln Gly Glu Asp Ala Cys Pro Gly Gly Ser Pro Glu Ser Gln 
145                 150                 155                 160 


Leu Val Cys Leu Gly Glu Ser Arg Ala Val Glu Glu His Ala Ala Met 
                165                 170                 175     


Asp Gly Ser Glu Gly Val Pro Gly Ser Arg Arg Trp Ala Gly Gly Gly 
            180                 185                 190         


Gly Gly Gly Gly Gly Ala Thr Tyr Val Phe Arg Val Arg Ala Gly Glu 
        195                 200                 205             


Leu Glu Pro Leu Leu Val Ala Ala Gly Gly Gly Gly Arg Ala Tyr Leu 
    210                 215                 220                 


Arg Pro Arg Asp Arg Gly Arg Thr Gln Ala Ser Pro Glu Lys Leu Glu 
225                 230                 235                 240 


Asn Arg Ser Glu Ala Pro Gly Ser Gly Gly Arg Gly Gly Ala Ala Gly 
                245                 250                 255     


Gly Gly Gly Gly Trp Thr Ser Arg Ala Pro Ser Pro Gln Ala Gly Arg 
            260                 265                 270         


Ser Leu Gln Glu Gly Ala Glu Gly Gly Gln Gly Cys Ser Glu Ala Trp 
        275                 280                 285             


Ala Thr Leu Gly Trp Ala Ala Ala Gly Gly Phe Gly Gly Gly Gly Gly 
    290                 295                 300                 


Ala Cys Thr Ala Gly Gly Gly Gly Gly Gly Tyr Arg Gly Gly Asp Ala 
305                 310                 315                 320 


Ser Glu Thr Asp Asn Leu Trp Ala Asp Gly Glu Asp Gly Val Ser Phe 
                325                 330                 335     


Ile His Pro Ser Ser Glu Leu Phe Leu Gln Pro Leu Ala Val Thr Glu 
            340                 345                 350         


Asn His Gly Glu Val Glu Ile Arg Arg His Leu Asn Cys Ser His Cys 
        355                 360                 365             


Pro Leu Arg Asp Cys Gln Trp Gln Ala Glu Leu Gln Leu Ala Glu Cys 
    370                 375                 380                 


Leu Cys Pro Glu Gly Met Glu Leu Ala Val Asp Asn Val Thr Cys Met 
385                 390                 395                 400 


Asp Leu Arg Lys Pro Pro Gly Pro 
                405             


<210>  896
<211>  320
<212>  PRT
<213>  Homo Sapiens

<400>  896

Gln Tyr Tyr Asp Tyr Asp Phe Pro Leu Ser Ile Tyr Gly Gln Ser Ser 
1               5                   10                  15      


Pro Asn Cys Ala Pro Glu Cys Asn Cys Pro Glu Ser Tyr Pro Ser Ala 
            20                  25                  30          


Met Tyr Cys Asp Glu Leu Lys Leu Lys Ser Val Pro Met Val Pro Pro 
        35                  40                  45              


Gly Ile Lys Tyr Leu Tyr Leu Arg Asn Asn Gln Ile Asp His Ile Asp 
    50                  55                  60                  


Glu Lys Ala Phe Glu Asn Val Thr Asp Leu Gln Trp Leu Ile Leu Asp 
65                  70                  75                  80  


His Asn Leu Leu Glu Asn Ser Lys Ile Lys Gly Arg Val Phe Ser Lys 
                85                  90                  95      


Leu Lys Gln Leu Lys Lys Leu His Ile Asn His Asn Asn Leu Thr Glu 
            100                 105                 110         


Ser Val Gly Pro Leu Pro Lys Ser Leu Glu Asp Leu Gln Leu Thr His 
        115                 120                 125             


Asn Lys Ile Thr Lys Leu Gly Ser Phe Glu Gly Leu Val Asn Leu Thr 
    130                 135                 140                 


Phe Ile His Leu Gln His Asn Arg Leu Lys Glu Asp Ala Val Ser Ala 
145                 150                 155                 160 


Ala Phe Lys Gly Leu Lys Ser Leu Glu Tyr Leu Asp Leu Ser Phe Asn 
                165                 170                 175     


Gln Ile Ala Arg Leu Pro Ser Gly Leu Pro Val Ser Leu Leu Thr Leu 
            180                 185                 190         


Tyr Leu Asp Asn Asn Lys Ile Ser Asn Ile Pro Asp Glu Tyr Phe Lys 
        195                 200                 205             


Arg Phe Asn Ala Leu Gln Tyr Leu Arg Leu Ser His Asn Glu Leu Ala 
    210                 215                 220                 


Asp Ser Gly Ile Pro Gly Asn Ser Phe Asn Val Ser Ser Leu Val Glu 
225                 230                 235                 240 


Leu Asp Leu Ser Tyr Asn Lys Leu Lys Asn Ile Pro Thr Val Asn Glu 
                245                 250                 255     


Asn Leu Glu Asn Tyr Tyr Leu Glu Val Asn Gln Leu Glu Lys Phe Asp 
            260                 265                 270         


Ile Lys Ser Phe Cys Lys Ile Leu Gly Pro Leu Ser Tyr Ser Lys Ile 
        275                 280                 285             


Lys His Leu Arg Leu Asp Gly Asn Arg Ile Ser Glu Thr Ser Leu Pro 
    290                 295                 300                 


Pro Asp Met Tyr Glu Cys Leu Arg Val Ala Asn Glu Val Thr Leu Asn 
305                 310                 315                 320 


<210>  897
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  897

Leu Arg Cys His Val Cys Thr Ser Ser Ser Asn Cys Lys His Ser Val 
1               5                   10                  15      


Val Cys Pro Ala Ser Ser Arg Phe Cys Lys Thr Thr Asn Thr Val Glu 
            20                  25                  30          


Pro Leu Arg Gly Asn Leu Val Lys Lys Asp Cys Ala Glu Ser Cys Thr 
        35                  40                  45              


Pro Ser Tyr Thr Leu Gln Gly Gln Val Ser Ser Gly Thr Ser Ser Thr 
    50                  55                  60                  


Gln Cys Cys Gln Glu Asp Leu Cys Asn Glu Lys Leu His Asn 
65                  70                  75              


<210>  898
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  898

Leu Met Cys Phe Ser Cys Leu Asn Gln Lys Ser Asn Leu Tyr Cys Leu 
1               5                   10                  15      


Lys Pro Thr Ile Cys Ser Asp Gln Asp Asn Tyr Cys Val Thr Val Ser 
            20                  25                  30          


Ala Ser Ala Gly Ile Gly Asn Leu Val Thr Phe Gly His Ser Leu Ser 
        35                  40                  45              


Lys Thr Cys Ser Pro Ala Cys Pro Ile Pro Glu Gly Val Asn Val Gly 
    50                  55                  60                  


Val Ala Ser Met Gly Ile Ser Cys Cys Gln Ser Phe Leu Cys Asn Phe 
65                  70                  75                  80  


Ser 
    


<210>  899
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  899

Lys Val Pro Val Pro Asp Ile Arg Thr Cys His Phe Cys Leu Val Glu 
1               5                   10                  15      


Asp Pro Ser Val Gly Cys Ile Ser Gly Ser Glu Lys Cys Thr Ile Ser 
            20                  25                  30          


Ser Ser Ser Leu Cys Met Val Ile Thr Ile Tyr Tyr Asp Val Lys Val 
        35                  40                  45              


Arg Phe Ile Val Arg Gly Cys Gly Gln Tyr Ile Ser Tyr Arg Cys Gln 
    50                  55                  60                  


Glu Lys Arg Asn Thr Tyr Phe Ala Glu Tyr Trp Tyr Gln Ala Gln Cys 
65                  70                  75                  80  


Cys Gln Tyr Asp Tyr Cys Asn Ser Trp Ser Ser Pro Gln Leu Gln Ser 
                85                  90                  95      


Ser Leu Pro Glu Pro His Asp Arg Pro Leu Ala Leu Pro Leu Ser Asp 
            100                 105                 110         


Ser Gln Ile Gln Trp Phe Tyr Gln Ala Leu Asn Leu Ser Leu Pro Leu 
        115                 120                 125             


Pro Asn Phe His Ala Gly Thr Glu Pro Asp Gly Leu Asp Pro Met Val 
    130                 135                 140                 


Thr Leu Ser Leu Asn Leu Gly Leu Ser Phe Ala Glu Leu Arg Arg Met 
145                 150                 155                 160 


Tyr Leu Phe Leu Asn Ser Ser Gly Leu Leu Val Leu Pro Gln Ala Gly 
                165                 170                 175     


Leu Leu Thr Pro His Pro Ser 
            180             


<210>  900
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  900

Lys Phe Val Pro Val Asn Trp Glu Pro Pro Gln Pro Leu Pro Phe Pro 
1               5                   10                  15      


Lys Tyr Leu Arg Cys Tyr Arg Cys Leu Leu Glu Thr Lys Glu Leu Gly 
            20                  25                  30          


Cys Leu Leu Gly Ser Asp Ile Cys Leu Thr Pro Ala Gly Ser Ser Cys 
        35                  40                  45              


Ile Thr Leu His Lys Lys Asn Ser Ser Gly Ser Asp Val Met Val Ser 
    50                  55                  60                  


Asp Cys Arg Ser Lys Glu Gln Met Ser Asp Cys Ser Asn Thr Arg Thr 
65                  70                  75                  80  


Ser Pro Val Ser Gly Phe Trp Ile Phe Ser Gln Tyr Cys Phe Leu Asp 
                85                  90                  95      


Phe Cys Asn Asp Pro Gln Asn Arg Gly Leu Tyr Thr Pro 
            100                 105                 


<210>  901
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  901

Asp Ile Arg Cys His Ser Cys Tyr Lys Val Pro Val Leu Gly Cys Val 
1               5                   10                  15      


Asp Arg Gln Ser Cys Arg Leu Glu Pro Gly Gln Gln Cys Leu Thr Thr 
            20                  25                  30          


His Ala Tyr Leu Gly Lys Met Trp Val Phe Ser Asn Leu Arg Cys Gly 
        35                  40                  45              


Thr Pro Glu Glu Pro Cys Gln Glu Ala Phe Asn Gln Thr Asn Arg Lys 
    50                  55                  60                  


Leu Gly Leu Thr Tyr Asn Thr Thr Cys Cys Asn Lys Asp Asn Cys Asn 
65                  70                  75                  80  


Ser 
    


<210>  902
<211>  85
<212>  PRT
<213>  Homo Sapiens

<400>  902

Asn Arg Met Arg Cys Tyr Asn Cys Gly Gly Ser Pro Ser Ser Ser Cys 
1               5                   10                  15      


Lys Glu Ala Val Thr Thr Cys Gly Glu Gly Arg Pro Gln Pro Gly Leu 
            20                  25                  30          


Glu Gln Ile Lys Leu Pro Gly Asn Pro Pro Val Thr Leu Ile His Gln 
        35                  40                  45              


His Pro Ala Cys Val Ala Ala His His Cys Asn Gln Val Glu Thr Glu 
    50                  55                  60                  


Ser Val Gly Asp Val Thr Tyr Pro Ala His Arg Asp Cys Tyr Leu Gly 
65                  70                  75                  80  


Asp Leu Cys Asn Ser 
                85  


<210>  903
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  903

Ala Asp Asn Met Gln Ala Ile Tyr Val Ala Leu Gly Glu Ala Val Glu 
1               5                   10                  15      


Leu Pro Cys Pro Ser Pro Pro Thr Leu His Gly Asp Glu His Leu Ser 
            20                  25                  30          


Trp Phe Cys Ser Pro Ala Ala Gly Ser Phe Thr Thr Leu Val Ala Gln 
        35                  40                  45              


Val Gln Val Gly Arg Pro Ala Pro Asp Pro Gly Lys Pro Gly Arg Glu 
    50                  55                  60                  


Ser Arg Leu Arg Leu Leu Gly Asn Tyr Ser Leu Trp Leu Glu Gly Ser 
65                  70                  75                  80  


Lys Glu Glu Asp Ala Gly Arg Tyr Trp Cys Ala Val Leu Gly Gln His 
                85                  90                  95      


His Asn Tyr Gln Asn Trp Arg Val Tyr Asp Val Leu Val Leu Lys Gly 
            100                 105                 110         


Ser Gln Leu Ser Ala Arg Ala Ala Asp Gly Ser Pro Cys Asn Val Leu 
        115                 120                 125             


Leu Cys Ser Val Val Pro Ser Arg Arg Met Asp Ser Val Thr Trp Gln 
    130                 135                 140                 


Glu Gly Lys Gly Pro Val Arg Gly Arg Val Gln Ser Phe Trp Gly Ser 
145                 150                 155                 160 


Glu Ala Ala Leu Leu Leu Val Cys Pro Gly Glu Gly Leu Ser Glu Pro 
                165                 170                 175     


Arg Ser Arg Arg Pro Arg Ile Ile Arg Cys Leu Met Thr His Asn Lys 
            180                 185                 190         


Gly Val Ser Phe Ser Leu Ala Ala Ser Ile Asp Ala Ser Pro Ala Leu 
        195                 200                 205             


Cys Ala Pro Ser Thr Gly Trp Asp Met Pro Trp 
    210                 215                 


<210>  904
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  904

Leu Trp Cys Gln Asp Cys Thr Leu Thr Thr Asn Ser Ser His Cys Thr 
1               5                   10                  15      


Pro Lys Gln Cys Gln Pro Ser Asp Thr Val Cys Ala Ser Val Arg Ile 
            20                  25                  30          


Thr Asp Pro Ser Ser Ser Arg Lys Asp His Ser Val Asn Lys Met Cys 
        35                  40                  45              


Ala Ser Ser Cys Asp Phe Val Lys Arg His Phe Phe Ser Asp Tyr Leu 
    50                  55                  60                  


Met Gly Phe Ile Asn Ser Gly Ile Leu Lys Val Asp Val Asp Cys Cys 
65                  70                  75                  80  


Glu Lys Asp Leu Cys Asn Gly Ala Ala Gly 
                85                  90  


<210>  905
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  905

Asp Ala Asn Leu Thr Ala Arg Gln Arg Asp Pro Glu Asp Ser Gln Arg 
1               5                   10                  15      


Thr Asp Glu Gly Asp Asn Arg Val Trp Cys His Val Cys Glu Arg Glu 
            20                  25                  30          


Asn Thr Phe Glu Cys Gln Asn Pro Arg Arg Cys Lys Trp Thr Glu Pro 
        35                  40                  45              


Tyr Cys Val Ile Ala Ala Val Lys Ile Phe Pro Arg Phe Phe Met Val 
    50                  55                  60                  


Ala Lys Gln Cys Ser Ala Gly Cys Ala Ala Met Glu Arg Pro Lys Pro 
65                  70                  75                  80  


Glu Glu Lys Arg Phe Leu Leu Glu Glu Pro Met Pro Phe Phe Tyr Leu 
                85                  90                  95      


Lys Cys Cys Lys Ile Arg Tyr Cys Asn Leu Glu Gly Pro Pro Ile Asn 
            100                 105                 110         


Ser Ser Val Phe Lys Glu Tyr Ala Gly 
        115                 120     


<210>  906
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  906

Ser Ala Gly Cys Ala Thr Thr Pro Ala Arg Asn Leu Ser Cys Tyr Gln 
1               5                   10                  15      


Cys Phe Lys Val Ser Ser Trp Thr Glu Cys Pro Pro Thr Trp Cys Ser 
            20                  25                  30          


Pro Leu Asp Gln Val Cys Ile Ser Asn Glu Val Val Val Ser Phe Lys 
        35                  40                  45              


Trp Ser Val Arg Val Leu Leu Ser Lys Arg Cys Ala Pro Arg Cys Pro 
    50                  55                  60                  


Asn Asp Asn Met Lys Phe Glu Trp Ser Pro Ala Pro Met Val Gln Gly 
65                  70                  75                  80  


Val Ile Thr Arg Arg Cys Cys Ser Trp Ala Leu Cys Asn Arg Ala Leu 
                85                  90                  95      


Thr Pro Gln Glu Gly 
            100     


<210>  907
<211>  266
<212>  PRT
<213>  Homo Sapiens

<400>  907

Tyr Glu Asp Gly Ile Tyr Ser Val Ile Gln Lys Lys Val Thr Trp Tyr 
1               5                   10                  15      


Glu Ala Leu Asn Met Cys Ser Gln Ser Gly Gly His Leu Ala Ser Val 
            20                  25                  30          


His Asn Gln Asn Gly Gln Leu Phe Leu Glu Asp Ile Val Lys Arg Asp 
        35                  40                  45              


Gly Phe Pro Leu Trp Val Gly Leu Ser Ser His Asp Gly Ser Glu Ser 
    50                  55                  60                  


Ser Phe Glu Trp Ser Asp Gly Ser Thr Phe Asp Tyr Ile Pro Trp Lys 
65                  70                  75                  80  


Gly Gln Thr Ser Pro Gly Asn Cys Val Leu Leu Asp Pro Lys Gly Thr 
                85                  90                  95      


Trp Lys His Glu Lys Cys Asn Ser Val Lys Asp Gly Ala Ile Cys Tyr 
            100                 105                 110         


Lys Pro Thr Lys Ser Lys Lys Leu Ser Arg Leu Thr Tyr Ser Ser Arg 
        115                 120                 125             


Cys Pro Ala Ala Lys Glu Asn Gly Ser Arg Trp Ile Gln Tyr Lys Gly 
    130                 135                 140                 


His Cys Tyr Lys Ser Asp Gln Ala Leu His Ser Phe Ser Glu Ala Lys 
145                 150                 155                 160 


Lys Leu Cys Ser Lys His Asp His Ser Ala Thr Ile Val Ser Ile Lys 
                165                 170                 175     


Asp Glu Asp Glu Asn Lys Phe Val Ser Arg Leu Met Arg Glu Asn Asn 
            180                 185                 190         


Asn Ile Thr Met Arg Val Trp Leu Gly Leu Ser Gln His Ser Val Asp 
        195                 200                 205             


Gln Ser Trp Ser Trp Leu Asp Gly Ser Glu Val Thr Phe Val Lys Trp 
    210                 215                 220                 


Glu Asn Lys Ser Lys Ser Gly Val Gly Arg Cys Ser Met Leu Ile Ala 
225                 230                 235                 240 


Ser Asn Glu Thr Trp Lys Lys Val Glu Cys Glu His Gly Phe Gly Arg 
                245                 250                 255     


Val Val Cys Lys Val Pro Leu Gly Pro Asp 
            260                 265     


<210>  908
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  908

Val Thr Met Lys Ser Val Lys Val Ser Glu Asn Phe Ser Cys Asn Ile 
1               5                   10                  15      


Thr Leu Met Cys Ser Val Lys Gly Ala Glu Lys Ser Val Leu Tyr Ser 
            20                  25                  30          


Trp Thr Pro Arg Glu Pro His Ala Ser Glu Ser Asn Gly Gly Ser Ile 
        35                  40                  45              


Leu Thr Val Ser Arg Thr Pro Cys Asp Pro Asp Leu Pro Tyr Ile Cys 
    50                  55                  60                  


Thr Ala Gln Asn Pro Val Ser Gln Arg Ser Ser Leu Pro Val His Val 
65                  70                  75                  80  


Gly Gln Phe Cys Thr Asp Pro Gly Ala Ser Arg Gly Gly Thr Thr Gly 
                85                  90                  95      


Glu Thr Val Val Gly Val Leu Gly Glu Pro Val Thr Leu Pro Leu Ala 
            100                 105                 110         


Leu Pro Ala Cys Arg Asp Thr Glu Lys Val Val Trp Leu Phe Asn Thr 
        115                 120                 125             


Ser Ile Ile Ser Lys Glu Arg Glu Glu Ala Ala Thr Ala Asp Pro Leu 
    130                 135                 140                 


Ile Lys Ser Arg Asp Pro Tyr Lys Asn Arg Val Trp Val Ser Ser Gln 
145                 150                 155                 160 


Asp Cys Ser Leu Lys Ile Ser Gln Leu Lys Ile Glu Asp Ala Gly Pro 
                165                 170                 175     


Tyr His Ala Tyr Val Cys Ser Glu Ala Ser Ser Val Thr Ser Met Thr 
            180                 185                 190         


His Val Thr Leu Leu Ile Tyr Arg Pro Glu Arg Asn Thr Lys 
        195                 200                 205     


<210>  909
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  909

Leu Asp Cys His Val Cys Ala Tyr Asn Gly Asp Asn Cys Phe Asn Pro 
1               5                   10                  15      


Met Arg Cys Pro Ala Met Val Ala Tyr Cys Met Thr Thr Arg Thr Ser 
            20                  25                  30          


Ala Ala Glu Ala Ile Trp Cys His Gln Cys Thr Gly Phe Gly Gly Cys 
        35                  40                  45              


Ser His Gly Ser Arg Cys Leu Arg Asp Ser Thr His Cys Val Thr Thr 
    50                  55                  60                  


Ala Thr Arg Val Leu Ser Asn Thr Glu Asp Leu Pro Leu Val Thr Lys 
65                  70                  75                  80  


Met Cys His Ile Gly Cys Pro Asp Ile Pro Ser Leu Gly Leu Gly Pro 
                85                  90                  95      


Tyr Val Ser Ile Ala Cys Cys Gln Thr Ser Leu Cys Asn His Asp 
            100                 105                 110     


<210>  910
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  910

Leu Gln Ile Gln Cys Tyr Gln Cys Glu Glu Phe Gln Leu Asn Asn Asp 
1               5                   10                  15      


Cys Ser Ser Pro Glu Phe Ile Val Asn Cys Thr Val Asn Val Gln Asp 
            20                  25                  30          


Met Cys Gln Lys Glu Val Met Glu Gln Ser Ala Gly Ile Met Tyr Arg 
        35                  40                  45              


Lys Ser Cys Ala Ser Ser Ala Ala Cys Leu Ile Ala Ser Ala Gly Tyr 
    50                  55                  60                  


Gln Ser Phe Cys Ser Pro Gly Lys Leu Asn Ser Val Cys Ile Ser Cys 
65                  70                  75                  80  


Cys Asn Thr Pro Leu Cys Asn Gly Pro Arg Pro Lys Lys Arg Gly Ser 
                85                  90                  95      


Ser 
    


<210>  911
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  911

Leu Arg Cys Tyr Val Cys Pro Glu Pro Thr Gly Val Ser Asp Cys Val 
1               5                   10                  15      


Thr Ile Ala Thr Cys Thr Thr Asn Glu Thr Met Cys Lys Thr Thr Leu 
            20                  25                  30          


Tyr Ser Arg Glu Ile Val Tyr Pro Phe Gln Gly Asp Ser Thr Val Thr 
        35                  40                  45              


Lys Ser Cys Ala Ser Lys Cys Lys Pro Ser Asp Val Asp Gly Ile Gly 
    50                  55                  60                  


Gln Thr Leu Pro Val Ser Cys Cys Asn Thr Glu Leu Cys Asn Val Asp 
65                  70                  75                  80  


Gly 
    


<210>  912
<211>  296
<212>  PRT
<213>  Homo Sapiens

<400>  912

Leu Glu Cys Tyr Ser Cys Val Gln Lys Ala Asp Asp Gly Cys Ser Pro 
1               5                   10                  15      


Asn Lys Met Lys Thr Val Lys Cys Ala Pro Gly Val Asp Val Cys Thr 
            20                  25                  30          


Glu Ala Val Gly Ala Val Glu Thr Ile His Gly Gln Phe Ser Leu Ala 
        35                  40                  45              


Val Arg Gly Cys Gly Ser Gly Leu Pro Gly Lys Asn Asp Arg Gly Leu 
    50                  55                  60                  


Asp Leu His Gly Leu Leu Ala Phe Ile Gln Leu Gln Gln Cys Ala Gln 
65                  70                  75                  80  


Asp Arg Cys Asn Ala Lys Leu Asn Leu Thr Ser Arg Ala Leu Asp Pro 
                85                  90                  95      


Ala Gly Asn Glu Ser Ala Tyr Pro Pro Asn Gly Val Glu Cys Tyr Ser 
            100                 105                 110         


Cys Val Gly Leu Ser Arg Glu Ala Cys Gln Gly Thr Ser Pro Pro Val 
        115                 120                 125             


Val Ser Cys Tyr Asn Ala Ser Asp His Val Tyr Lys Gly Cys Phe Asp 
    130                 135                 140                 


Gly Asn Val Thr Leu Thr Ala Ala Asn Val Thr Val Ser Leu Pro Val 
145                 150                 155                 160 


Arg Gly Cys Val Gln Asp Glu Phe Cys Thr Arg Asp Gly Val Thr Gly 
                165                 170                 175     


Pro Gly Phe Thr Leu Ser Gly Ser Cys Cys Gln Gly Ser Arg Cys Asn 
            180                 185                 190         


Ser Asp Leu Arg Asn Lys Thr Tyr Phe Ser Pro Arg Ile Pro Pro Leu 
        195                 200                 205             


Val Arg Leu Pro Pro Pro Glu Pro Thr Thr Val Ala Ser Thr Thr Ser 
    210                 215                 220                 


Val Thr Thr Ser Thr Ser Ala Pro Val Arg Pro Thr Ser Thr Thr Lys 
225                 230                 235                 240 


Pro Met Pro Ala Pro Thr Ser Gln Thr Pro Arg Gln Gly Val Glu His 
                245                 250                 255     


Glu Ala Ser Arg Asp Glu Glu Pro Arg Leu Thr Gly Gly Ala Ala Gly 
            260                 265                 270         


His Gln Asp Arg Ser Asn Ser Gly Gln Tyr Pro Ala Lys Gly Gly Pro 
        275                 280                 285             


Gln Gln Pro His Asn Lys Gly Cys 
    290                 295     


<210>  913
<211>  170
<212>  PRT
<213>  Homo Sapiens

<400>  913

Leu Pro Arg Met Ser Cys Gly Ala Gly Cys Tyr Lys Thr Gln Lys Gly 
1               5                   10                  15      


Thr Ala Arg Gly Val Val Gly Phe Lys Gly Cys Ser Ser Ser Ser Ser 
            20                  25                  30          


Tyr Pro Ala Gln Ile Ser Tyr Leu Val Ser Pro Pro Gly Val Ser Ile 
        35                  40                  45              


Ala Ser Tyr Ser Arg Val Cys Arg Ser Tyr Leu Cys Asn Asn Leu Thr 
    50                  55                  60                  


Asn Leu Glu Pro Phe Val Lys Leu Lys Ala Ser Thr Pro Lys Ser Ile 
65                  70                  75                  80  


Thr Ser Ala Ser Cys Ser Cys Pro Thr Cys Val Gly Glu His Met Lys 
                85                  90                  95      


Asp Cys Leu Pro Asn Phe Val Thr Thr Asn Ser Cys Pro Leu Ala Ala 
            100                 105                 110         


Ser Thr Cys Tyr Ser Ser Thr Leu Lys Phe Gln Ala Gly Phe Leu Asn 
        115                 120                 125             


Thr Thr Phe Leu Leu Met Gly Cys Ala Arg Glu His Asn Gln Leu Leu 
    130                 135                 140                 


Ala Asp Phe His His Ile Gly Ser Ile Lys Val Thr Glu Val Leu Asn 
145                 150                 155                 160 


Ile Leu Glu Lys Ser Gln Ile Val Gly Ala 
                165                 170 


<210>  914
<211>  200
<212>  PRT
<213>  Homo Sapiens

<400>  914

Leu Gln Cys Tyr Ser Phe Glu His Thr Tyr Phe Gly Pro Phe Asp Leu 
1               5                   10                  15      


Arg Ala Met Lys Leu Pro Ser Ile Ser Cys Pro His Glu Cys Phe Glu 
            20                  25                  30          


Ala Ile Leu Ser Leu Asp Thr Gly Tyr Arg Ala Pro Val Thr Leu Val 
        35                  40                  45              


Arg Lys Gly Cys Trp Thr Gly Pro Pro Ala Gly Gln Thr Gln Ser Asn 
    50                  55                  60                  


Ala Asp Ala Leu Pro Pro Asp Tyr Ser Val Val Arg Gly Cys Thr Thr 
65                  70                  75                  80  


Asp Lys Cys Asn Ala His Leu Met Thr His Asp Ala Leu Pro Asn Leu 
                85                  90                  95      


Ser Gln Ala Pro Asp Pro Pro Thr Leu Ser Gly Ala Glu Cys Tyr Ala 
            100                 105                 110         


Cys Ile Gly Val His Gln Asp Asp Cys Ala Ile Gly Arg Ser Arg Arg 
        115                 120                 125             


Val Gln Cys His Gln Asp Gln Thr Ala Cys Phe Gln Gly Asn Gly Arg 
    130                 135                 140                 


Met Thr Val Gly Asn Phe Ser Val Pro Val Tyr Ile Arg Thr Cys His 
145                 150                 155                 160 


Arg Pro Ser Cys Thr Thr Glu Gly Ser Thr Ser Pro Trp Thr Ala Ile 
                165                 170                 175     


Asp Leu Gln Gly Ser Cys Cys Glu Gly Tyr Leu Cys Asn Arg Lys Ser 
            180                 185                 190         


Met Thr Gln Pro Phe Thr Ser Ala 
        195                 200 


<210>  915
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  915

Ala Gln Ser Arg Asp Phe Thr Val Lys Asp Ile Ile Tyr Leu His Pro 
1               5                   10                  15      


Ser Thr Thr Pro Tyr Pro Gly Gly Phe Lys Cys Phe Thr Cys Glu Lys 
            20                  25                  30          


Ala Ala Asp Asn Tyr Glu Cys Asn Arg Trp Ala Pro Asp Ile Tyr Cys 
        35                  40                  45              


Pro Arg Glu Thr Arg Tyr Cys Tyr Thr Gln His Thr Met Glu Val Thr 
    50                  55                  60                  


Gly Asn Ser Ile Ser Val Thr Lys Arg Cys Val Pro Leu Glu Glu Cys 
65                  70                  75                  80  


Leu Ser Thr Gly Cys Arg Asp Ser Glu His Glu Gly His Lys Val Cys 
                85                  90                  95      


Thr Ser Cys Cys Glu Gly Asn Ile Cys Asn Leu Pro Leu Pro Arg Asn 
            100                 105                 110         


Glu Thr Asp Ala Thr Phe Ala Thr Thr Ser Pro Ile Asn Gln Thr Asn 
        115                 120                 125             


<210>  916
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  916

Lys Asn Ile Asn Phe Tyr Asn Val Arg Pro Pro Leu Asp Pro Thr Pro 
1               5                   10                  15      


Phe Pro Asn Ser Phe Lys Cys Phe Thr Cys Glu Asn Ala Gly Asp Asn 
            20                  25                  30          


Tyr Asn Cys Asn Arg Trp Ala Glu Asp Lys Trp Cys Pro Gln Asn Thr 
        35                  40                  45              


Gln Tyr Cys Leu Thr Val His His Phe Thr Ser His Gly Arg Ser Thr 
    50                  55                  60                  


Ser Ile Thr Lys Lys Cys Ala Ser Arg Ser Glu Cys His Phe Val Gly 
65                  70                  75                  80  


Cys His His Ser Arg Asp Ser Glu His Thr Glu Cys Arg Ser Cys Cys 
                85                  90                  95      


Glu Gly Met Ile Cys Asn Val Glu Leu Pro Thr Asn His Thr Asn Ala 
            100                 105                 110         


Val Phe Ala Val Met His Ala Gln Arg Thr Ser Gly Ser 
        115                 120                 125 


<210>  917
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  917

Leu Ser Cys Val Gln Cys Asn Ser Trp Glu Lys Ser Cys Val Asn Ser 
1               5                   10                  15      


Ile Ala Ser Glu Cys Pro Ser His Ala Asn Thr Ser Cys Ile Ser Ser 
            20                  25                  30          


Ser Ala Ser Ser Ser Leu Glu Thr Pro Val Arg Leu Tyr Gln Asn Met 
        35                  40                  45              


Phe Cys Ser Ala Glu Asn Cys Ser Glu Glu Thr His Ile Thr Ala Phe 
    50                  55                  60                  


Thr Val His Val Ser Ala Glu Glu His Phe His Phe Val Ser Gln Cys 
65                  70                  75                  80  


Cys Gln Gly Lys Glu Cys Ser Asn Thr Ser Asp Ala Leu Asp Pro Pro 
                85                  90                  95      


Leu Lys Asn Val Ser Ser Asn Ala Glu Cys Pro Ala Cys Tyr Glu Ser 
            100                 105                 110         


Asn Gly Thr Ser Cys His Gly Lys Pro Trp Lys Cys Tyr Glu Glu Glu 
        115                 120                 125             


Gln Cys Val Phe Leu Val Ala Glu Leu Lys Asn Asp Ile Glu Ser Lys 
    130                 135                 140                 


Ser Leu Val Leu Lys Gly Cys Ser Asn Val Ser Asn Ala Thr Cys Gln 
145                 150                 155                 160 


Phe Leu Ser Gly Glu Asn Lys Thr Leu Gly Gly Val Ile Phe Arg Lys 
                165                 170                 175     


Phe Glu Cys Ala Asn Val Asn Ser Leu Thr Pro Thr Ser Ala Pro Thr 
            180                 185                 190         


Thr Ser His Asn 
        195     


<210>  918
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  918

Gln Ser Leu Gln Val Lys Pro Leu Gln Val Glu Pro Pro Glu Pro Val 
1               5                   10                  15      


Val Ala Val Ala Leu Gly Ala Ser Arg Gln Leu Thr Cys Arg Leu Ala 
            20                  25                  30          


Cys Ala Asp Arg Gly Ala Ser Val Gln Trp Arg Gly Leu Asp Thr Ser 
        35                  40                  45              


Leu Gly Ala Val Gln Ser Asp Thr Gly Arg Ser Val Leu Thr Val Arg 
    50                  55                  60                  


Asn Ala Ser Leu Ser Ala Ala Gly Thr Arg Val Cys Val Gly Ser Cys 
65                  70                  75                  80  


Gly Gly Arg Thr Phe Gln His Thr Val Gln Leu Leu Val Tyr Ala Phe 
                85                  90                  95      


Pro Asp Gln Leu Thr Val Ser Pro Ala Ala Leu Val Pro Gly Asp Pro 
            100                 105                 110         


Glu Val Ala Cys Thr Ala His Lys Val Thr Pro Val Asp Pro Asn Ala 
        115                 120                 125             


Leu Ser Phe Ser Leu Leu Val Gly Gly Gln Glu Leu Glu Gly Ala Gln 
    130                 135                 140                 


Ala Leu Gly Pro Glu Val Gln Glu Glu Glu Glu Glu Pro Gln Gly Asp 
145                 150                 155                 160 


Glu Asp Val Leu Phe Arg Val Thr Glu Arg Trp Arg Leu Pro Pro Leu 
                165                 170                 175     


Gly Thr Pro Val Pro Pro Ala Leu Tyr Cys Gln Ala Thr Met Arg Leu 
            180                 185                 190         


Pro Gly Leu Glu Leu Ser His Arg Gln Ala Ile Pro Val Leu His Ser 
        195                 200                 205             


Pro Thr Ser Pro Glu Pro Pro Asp Thr Thr Ser Pro Glu Pro Pro Asn 
    210                 215                 220                 


Thr Thr Ser Pro Glu Ser Pro Asp Thr Thr Ser Pro Glu Ser Pro Asp 
225                 230                 235                 240 


Thr Thr Ser Gln Glu Pro Pro Asp Thr Thr Ser Gln Glu Pro Pro Asp 
                245                 250                 255     


Thr Thr Ser Gln Glu Pro Pro Asp Thr Thr Ser Pro Glu Pro Pro Asp 
            260                 265                 270         


Lys Thr Ser Pro Glu Pro Ala Pro Gln Gln Gly Ser Thr His Thr Pro 
        275                 280                 285             


Arg Ser Pro Gly Ser Thr Arg Thr Arg Arg Pro Glu Ile Ser Gln Ala 
    290                 295                 300                 


Gly Pro Thr Gln Gly Glu Val Ile Pro Thr Gly Ser Ser Lys Pro Ala 
305                 310                 315                 320 


Gly Asp Gln 
            


<210>  919
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  919

Gly His Trp Gly Ala Trp Met Pro Ser Ser Ile Ser Ala Phe Glu Gly 
1               5                   10                  15      


Thr Cys Val Ser Ile Pro Cys Arg Phe Asp Phe Pro Asp Glu Leu Arg 
            20                  25                  30          


Pro Ala Val Val His Gly Val Trp Tyr Phe Asn Ser Pro Tyr Pro Lys 
        35                  40                  45              


Asn Tyr Pro Pro Val Val Phe Lys Ser Arg Thr Gln Val Val His Glu 
    50                  55                  60                  


Ser Phe Gln Gly Arg Ser Arg Leu Leu Gly Asp Leu Gly Leu Arg Asn 
65                  70                  75                  80  


Cys Thr Leu Leu Leu Ser Asn Val Ser Pro Glu Leu Gly Gly Lys Tyr 
                85                  90                  95      


Tyr Phe Arg Gly Asp Leu Gly Gly Tyr Asn Gln Tyr Thr Phe Ser Glu 
            100                 105                 110         


His Ser Val Leu Asp Ile Val Asn Thr Pro Asn Ile Val Val Pro Pro 
        115                 120                 125             


Glu Val Val Ala Gly Thr Glu Val Glu Val Ser Cys Met Val Pro Asp 
    130                 135                 140                 


Asn Cys Pro Glu Leu Arg Pro Glu Leu Ser Trp Leu Gly His Glu Gly 
145                 150                 155                 160 


Leu Gly Glu Pro Ala Val Leu Gly Arg Leu Arg Glu Asp Glu Gly Thr 
                165                 170                 175     


Trp Val Gln Val Ser Leu Leu His Phe Val Pro Thr Arg Glu Ala Asn 
            180                 185                 190         


Gly His Arg Leu Gly Cys Gln Ala Ser Phe Pro Asn Thr Thr Leu Gln 
        195                 200                 205             


Phe Glu Gly Tyr Ala Ser Met Asp Val Lys Tyr Pro Pro Val Ile Val 
    210                 215                 220                 


Glu Met Asn Ser Ser Val Glu Ala Ile Glu Gly Ser His Val Ser Leu 
225                 230                 235                 240 


Leu Cys Gly Ala Asp Ser Asn Pro Pro Pro Leu Leu Thr Trp Met Arg 
                245                 250                 255     


Asp Gly Thr Val Leu Arg Glu Ala Val Ala Glu Ser Leu Leu Leu Glu 
            260                 265                 270         


Leu Glu Glu Val Thr Pro Ala Glu Asp Gly Val Tyr Ala Cys Leu Ala 
        275                 280                 285             


Glu Asn Ala Tyr Gly Gln Asp Asn Arg Thr Val Gly Leu Ser Val Met 
    290                 295                 300                 


Tyr Ala Pro Trp Lys Pro Thr Val Asn Gly Thr Met Val Ala Val Glu 
305                 310                 315                 320 


Gly Glu Thr Val Ser Ile Leu Cys Ser Thr Gln Ser Asn Pro Asp Pro 
                325                 330                 335     


Ile Leu Thr Ile Phe Lys Glu Lys Gln Ile Leu Ser Thr Val Ile Tyr 
            340                 345                 350         


Glu Ser Glu Leu Gln Leu Glu Leu Pro Ala Val Ser Pro Glu Asp Asp 
        355                 360                 365             


Gly Glu Tyr Trp Cys Val Ala Glu Asn Gln Tyr Gly Gln Arg Ala Thr 
    370                 375                 380                 


Ala Phe Asn Leu Ser Val Glu Phe Ala Pro Val Leu Leu Leu Glu Ser 
385                 390                 395                 400 


His Cys Ala Ala Ala Arg Asp Thr Val Gln Cys Leu Cys Val Val Lys 
                405                 410                 415     


Ser Asn Pro Glu Pro Ser Val Ala Phe Glu Leu Pro Ser Arg Asn Val 
            420                 425                 430         


Thr Val Asn Glu Ser Glu Arg Glu Phe Val Tyr Ser Glu Arg Ser Gly 
        435                 440                 445             


Leu Val Leu Thr Ser Ile Leu Thr Leu Arg Gly Gln Ala Gln Ala Pro 
    450                 455                 460                 


Pro Arg Val Ile Cys Thr Ala Arg Asn Leu Tyr Gly Ala Lys Ser Leu 
465                 470                 475                 480 


Glu Leu Pro Phe Gln Gly Ala His Arg Leu Met Trp Ala Lys Ile Gly 
                485                 490                 495     


Pro 
    


<210>  920
<211>  862
<212>  PRT
<213>  Homo Sapiens

<400>  920

Ala Ala Glu Leu Ser Tyr Ser Leu Arg Gly Asn Trp Ser Ile Cys Asn 
1               5                   10                  15      


Gly Asn Gly Ser Leu Glu Leu Pro Gly Ala Val Pro Gly Cys Val His 
            20                  25                  30          


Ser Ala Leu Phe Gln Gln Gly Leu Ile Gln Asp Ser Tyr Tyr Arg Phe 
        35                  40                  45              


Asn Asp Leu Asn Tyr Arg Trp Val Ser Leu Asp Asn Trp Thr Tyr Ser 
    50                  55                  60                  


Lys Glu Phe Lys Ile Pro Phe Glu Ile Ser Lys Trp Gln Lys Val Asn 
65                  70                  75                  80  


Leu Ile Leu Glu Gly Val Asp Thr Val Ser Lys Ile Leu Phe Asn Glu 
                85                  90                  95      


Val Thr Ile Gly Glu Thr Asp Asn Met Phe Asn Arg Tyr Ser Phe Asp 
            100                 105                 110         


Ile Thr Asn Val Val Arg Asp Val Asn Ser Ile Glu Leu Arg Phe Gln 
        115                 120                 125             


Ser Ala Val Leu Tyr Ala Ala Gln Gln Ser Lys Ala His Thr Arg Tyr 
    130                 135                 140                 


Gln Val Pro Pro Asp Cys Pro Pro Leu Val Gln Lys Gly Glu Cys His 
145                 150                 155                 160 


Val Asn Phe Val Arg Lys Glu Gln Cys Ser Phe Ser Trp Asp Trp Gly 
                165                 170                 175     


Pro Ser Phe Pro Thr Gln Gly Ile Trp Lys Asp Val Arg Ile Glu Ala 
            180                 185                 190         


Tyr Asn Ile Cys His Leu Asn Tyr Phe Thr Phe Ser Pro Ile Tyr Asp 
        195                 200                 205             


Lys Ser Ala Gln Glu Trp Asn Leu Glu Ile Glu Ser Thr Phe Asp Val 
    210                 215                 220                 


Val Ser Ser Lys Pro Val Gly Gly Gln Val Ile Val Ala Ile Pro Lys 
225                 230                 235                 240 


Leu Gln Thr Gln Gln Thr Tyr Ser Ile Glu Leu Gln Pro Gly Lys Arg 
                245                 250                 255     


Ile Val Glu Leu Phe Val Asn Ile Ser Lys Asn Ile Thr Val Glu Thr 
            260                 265                 270         


Trp Trp Pro His Gly His Gly Asn Gln Thr Gly Tyr Asn Met Thr Val 
        275                 280                 285             


Leu Phe Glu Leu Asp Gly Gly Leu Asn Ile Glu Lys Ser Ala Lys Val 
    290                 295                 300                 


Tyr Phe Arg Thr Val Glu Leu Ile Glu Glu Pro Ile Lys Gly Ser Pro 
305                 310                 315                 320 


Gly Leu Ser Phe Tyr Phe Lys Ile Asn Gly Phe Pro Ile Phe Leu Lys 
                325                 330                 335     


Gly Ser Asn Trp Ile Pro Ala Asp Ser Phe Gln Asp Arg Val Thr Ser 
            340                 345                 350         


Glu Leu Leu Arg Leu Leu Leu Gln Ser Val Val Asp Ala Asn Met Asn 
        355                 360                 365             


Thr Leu Arg Val Trp Gly Gly Gly Ile Tyr Glu Gln Asp Glu Phe Tyr 
    370                 375                 380                 


Glu Leu Cys Asp Glu Leu Gly Ile Met Val Trp Gln Asp Phe Met Phe 
385                 390                 395                 400 


Ala Cys Ala Leu Tyr Pro Thr Asp Gln Gly Phe Leu Asp Ser Val Thr 
                405                 410                 415     


Ala Glu Val Ala Tyr Gln Ile Lys Arg Leu Lys Ser His Pro Ser Ile 
            420                 425                 430         


Ile Ile Trp Ser Gly Asn Asn Glu Asn Glu Glu Ala Leu Met Met Asn 
        435                 440                 445             


Trp Tyr His Ile Ser Phe Thr Asp Arg Pro Ile Tyr Ile Lys Asp Tyr 
    450                 455                 460                 


Val Thr Leu Tyr Val Lys Asn Ile Arg Glu Leu Val Leu Ala Gly Asp 
465                 470                 475                 480 


Lys Ser Arg Pro Phe Ile Thr Ser Ser Pro Thr Asn Gly Ala Glu Thr 
                485                 490                 495     


Val Ala Glu Ala Trp Val Ser Gln Asn Pro Asn Ser Asn Tyr Phe Gly 
            500                 505                 510         


Asp Val His Phe Tyr Asp Tyr Ile Ser Asp Cys Trp Asn Trp Lys Val 
        515                 520                 525             


Phe Pro Lys Ala Arg Phe Ala Ser Glu Tyr Gly Tyr Gln Ser Trp Pro 
    530                 535                 540                 


Ser Phe Ser Thr Leu Glu Lys Val Ser Ser Thr Glu Asp Trp Ser Phe 
545                 550                 555                 560 


Asn Ser Lys Phe Ser Leu His Arg Gln His His Glu Gly Gly Asn Lys 
                565                 570                 575     


Gln Met Leu Tyr Gln Ala Gly Leu His Phe Lys Leu Pro Gln Ser Thr 
            580                 585                 590         


Asp Pro Leu Arg Thr Phe Lys Asp Thr Ile Tyr Leu Thr Gln Val Met 
        595                 600                 605             


Gln Ala Gln Cys Val Lys Thr Glu Thr Glu Phe Tyr Arg Arg Ser Arg 
    610                 615                 620                 


Ser Glu Ile Val Asp Gln Gln Gly His Thr Met Gly Ala Leu Tyr Trp 
625                 630                 635                 640 


Gln Leu Asn Asp Ile Trp Gln Ala Pro Ser Trp Ala Ser Leu Glu Tyr 
                645                 650                 655     


Gly Gly Lys Trp Lys Met Leu His Tyr Phe Ala Gln Asn Phe Phe Ala 
            660                 665                 670         


Pro Leu Leu Pro Val Gly Phe Glu Asn Glu Asn Met Phe Tyr Ile Tyr 
        675                 680                 685             


Gly Val Ser Asp Leu His Ser Asp Tyr Ser Met Thr Leu Ser Val Arg 
    690                 695                 700                 


Val His Thr Trp Ser Ser Leu Glu Pro Val Cys Ser Arg Val Thr Glu 
705                 710                 715                 720 


Arg Phe Val Met Lys Gly Gly Glu Ala Val Cys Leu Tyr Glu Glu Pro 
                725                 730                 735     


Val Ser Glu Leu Leu Arg Arg Cys Gly Asn Cys Thr Arg Glu Ser Cys 
            740                 745                 750         


Val Val Ser Phe Tyr Leu Ser Ala Asp His Glu Leu Leu Ser Pro Thr 
        755                 760                 765             


Asn Tyr His Phe Leu Ser Ser Pro Lys Glu Ala Val Gly Leu Cys Lys 
    770                 775                 780                 


Ala Gln Ile Thr Ala Ile Ile Ser Gln Gln Gly Asp Ile Phe Val Phe 
785                 790                 795                 800 


Asp Leu Glu Thr Ser Ala Val Ala Pro Phe Val Trp Leu Asp Val Gly 
                805                 810                 815     


Ser Ile Pro Gly Arg Phe Ser Asp Asn Gly Phe Leu Met Thr Glu Lys 
            820                 825                 830         


Thr Arg Thr Ile Leu Phe Tyr Pro Trp Glu Pro Thr Ser Lys Asn Glu 
        835                 840                 845             


Leu Glu Gln Ser Phe His Val Thr Ser Leu Thr Asp Ile Tyr 
    850                 855                 860         


<210>  921
<211>  709
<212>  PRT
<213>  Homo Sapiens

<400>  921

His Thr Val Glu Leu Asn Asn Met Phe Gly Gln Ile Gln Ser Pro Gly 
1               5                   10                  15      


Tyr Pro Asp Ser Tyr Pro Ser Asp Ser Glu Val Thr Trp Asn Ile Thr 
            20                  25                  30          


Val Pro Asp Gly Phe Arg Ile Lys Leu Tyr Phe Met His Phe Asn Leu 
        35                  40                  45              


Glu Ser Ser Tyr Leu Cys Glu Tyr Asp Tyr Val Lys Val Glu Thr Glu 
    50                  55                  60                  


Asp Gln Val Leu Ala Thr Phe Cys Gly Arg Glu Thr Thr Asp Thr Glu 
65                  70                  75                  80  


Gln Thr Pro Gly Gln Glu Val Val Leu Ser Pro Gly Ser Phe Met Ser 
                85                  90                  95      


Ile Thr Phe Arg Ser Asp Phe Ser Asn Glu Glu Arg Phe Thr Gly Phe 
            100                 105                 110         


Asp Ala His Tyr Met Ala Val Asp Val Asp Glu Cys Lys Glu Arg Glu 
        115                 120                 125             


Asp Glu Glu Leu Ser Cys Asp His Tyr Cys His Asn Tyr Ile Gly Gly 
    130                 135                 140                 


Tyr Tyr Cys Ser Cys Arg Phe Gly Tyr Ile Leu His Thr Asp Asn Arg 
145                 150                 155                 160 


Thr Cys Arg Val Glu Cys Ser Asp Asn Leu Phe Thr Gln Arg Thr Gly 
                165                 170                 175     


Val Ile Thr Ser Pro Asp Phe Pro Asn Pro Tyr Pro Lys Ser Ser Glu 
            180                 185                 190         


Cys Leu Tyr Thr Ile Glu Leu Glu Glu Gly Phe Met Val Asn Leu Gln 
        195                 200                 205             


Phe Glu Asp Ile Phe Asp Ile Glu Asp His Pro Glu Val Pro Cys Pro 
    210                 215                 220                 


Tyr Asp Tyr Ile Lys Ile Lys Val Gly Pro Lys Val Leu Gly Pro Phe 
225                 230                 235                 240 


Cys Gly Glu Lys Ala Pro Glu Pro Ile Ser Thr Gln Ser His Ser Val 
                245                 250                 255     


Leu Ile Leu Phe His Ser Asp Asn Ser Gly Glu Asn Arg Gly Trp Arg 
            260                 265                 270         


Leu Ser Tyr Arg Ala Ala Gly Asn Glu Cys Pro Glu Leu Gln Pro Pro 
        275                 280                 285             


Val His Gly Lys Ile Glu Pro Ser Gln Ala Lys Tyr Phe Phe Lys Asp 
    290                 295                 300                 


Gln Val Leu Val Ser Cys Asp Thr Gly Tyr Lys Val Leu Lys Asp Asn 
305                 310                 315                 320 


Val Glu Met Asp Thr Phe Gln Ile Glu Cys Leu Lys Asp Gly Thr Trp 
                325                 330                 335     


Ser Asn Lys Ile Pro Thr Cys Lys Ile Val Asp Cys Arg Ala Pro Gly 
            340                 345                 350         


Glu Leu Glu His Gly Leu Ile Thr Phe Ser Thr Arg Asn Asn Leu Thr 
        355                 360                 365             


Thr Tyr Lys Ser Glu Ile Lys Tyr Ser Cys Gln Glu Pro Tyr Tyr Lys 
    370                 375                 380                 


Met Leu Asn Asn Asn Thr Gly Ile Tyr Thr Cys Ser Ala Gln Gly Val 
385                 390                 395                 400 


Trp Met Asn Lys Val Leu Gly Arg Ser Leu Pro Thr Cys Leu Pro Glu 
                405                 410                 415     


Cys Gly Gln Pro Ser Arg Ser Leu Pro Ser Leu Val Lys Arg Ile Ile 
            420                 425                 430         


Gly Gly Arg Asn Ala Glu Pro Gly Leu Phe Pro Trp Gln Ala Leu Ile 
        435                 440                 445             


Val Val Glu Asp Thr Ser Arg Val Pro Asn Asp Lys Trp Phe Gly Ser 
    450                 455                 460                 


Gly Ala Leu Leu Ser Ala Ser Trp Ile Leu Thr Ala Ala His Val Leu 
465                 470                 475                 480 


Arg Ser Gln Arg Arg Asp Thr Thr Val Ile Pro Val Ser Lys Glu His 
                485                 490                 495     


Val Thr Val Tyr Leu Gly Leu His Asp Val Arg Asp Lys Ser Gly Ala 
            500                 505                 510         


Val Asn Ser Ser Ala Ala Arg Val Val Leu His Pro Asp Phe Asn Ile 
        515                 520                 525             


Gln Asn Tyr Asn His Asp Ile Ala Leu Val Gln Leu Gln Glu Pro Val 
    530                 535                 540                 


Pro Leu Gly Pro His Val Met Pro Val Cys Leu Pro Arg Leu Glu Pro 
545                 550                 555                 560 


Glu Gly Pro Ala Pro His Met Leu Gly Leu Val Ala Gly Trp Gly Ile 
                565                 570                 575     


Ser Asn Pro Asn Val Thr Val Asp Glu Ile Ile Ser Ser Gly Thr Arg 
            580                 585                 590         


Thr Leu Ser Asp Val Leu Gln Tyr Val Lys Leu Pro Val Val Pro His 
        595                 600                 605             


Ala Glu Cys Lys Thr Ser Tyr Glu Ser Arg Ser Gly Asn Tyr Ser Val 
    610                 615                 620                 


Thr Glu Asn Met Phe Cys Ala Gly Tyr Tyr Glu Gly Gly Lys Asp Thr 
625                 630                 635                 640 


Cys Leu Gly Asp Ser Gly Gly Ala Phe Val Ile Phe Asp Asp Leu Ser 
                645                 650                 655     


Gln Arg Trp Val Val Gln Gly Leu Val Ser Trp Gly Gly Pro Glu Glu 
            660                 665                 670         


Cys Gly Ser Lys Gln Val Tyr Gly Val Tyr Thr Lys Val Ser Asn Tyr 
        675                 680                 685             


Val Asp Trp Val Trp Glu Gln Met Gly Leu Pro Gln Ser Val Val Glu 
    690                 695                 700                 


Pro Gln Val Glu Arg 
705                 


<210>  922
<211>  474
<212>  PRT
<213>  Homo Sapiens

<400>  922

Ser Pro Gly Leu Ala Pro Gln Ser Arg Gly His Leu Cys Arg Thr Arg 
1               5                   10                  15      


Pro Thr Asp Leu Val Phe Val Val Asp Ser Ser Arg Ser Val Arg Pro 
            20                  25                  30          


Val Glu Phe Glu Lys Val Lys Val Phe Leu Ser Gln Val Ile Glu Ser 
        35                  40                  45              


Leu Asp Val Gly Pro Asn Ala Thr Arg Val Gly Met Val Asn Tyr Ala 
    50                  55                  60                  


Ser Thr Val Lys Gln Glu Phe Ser Leu Arg Ala His Val Ser Lys Ala 
65                  70                  75                  80  


Ala Leu Leu Gln Ala Val Arg Arg Ile Gln Pro Leu Ser Thr Gly Thr 
                85                  90                  95      


Met Thr Gly Leu Ala Ile Gln Phe Ala Ile Thr Lys Ala Phe Gly Asp 
            100                 105                 110         


Ala Glu Gly Gly Arg Ser Arg Ser Pro Asp Ile Ser Lys Val Val Ile 
        115                 120                 125             


Val Val Thr Asp Gly Arg Pro Gln Asp Ser Val Gln Asp Val Ser Ala 
    130                 135                 140                 


Arg Ala Arg Ala Ser Gly Val Glu Leu Phe Ala Ile Gly Val Gly Ser 
145                 150                 155                 160 


Val Asp Lys Ala Thr Leu Arg Gln Ile Ala Ser Glu Pro Gln Asp Glu 
                165                 170                 175     


His Val Asp Tyr Val Glu Ser Tyr Ser Val Ile Glu Lys Leu Ser Arg 
            180                 185                 190         


Lys Phe Gln Glu Ala Phe Cys Val Val Ser Asp Leu Cys Ala Thr Gly 
        195                 200                 205             


Asp His Asp Cys Glu Gln Val Cys Ile Ser Ser Pro Gly Ser Tyr Thr 
    210                 215                 220                 


Cys Ala Cys His Glu Gly Phe Thr Leu Asn Ser Asp Gly Lys Thr Cys 
225                 230                 235                 240 


Asn Val Cys Ser Gly Gly Gly Gly Ser Ser Ala Thr Asp Leu Val Phe 
                245                 250                 255     


Leu Ile Asp Gly Ser Lys Ser Val Arg Pro Glu Asn Phe Glu Leu Val 
            260                 265                 270         


Lys Lys Phe Ile Ser Gln Ile Val Asp Thr Leu Asp Val Ser Asp Lys 
        275                 280                 285             


Leu Ala Gln Val Gly Leu Val Gln Tyr Ser Ser Ser Val Arg Gln Glu 
    290                 295                 300                 


Phe Pro Leu Gly Arg Phe His Thr Lys Lys Asp Ile Lys Ala Ala Val 
305                 310                 315                 320 


Arg Asn Met Ser Tyr Met Glu Lys Gly Thr Met Thr Gly Ala Ala Leu 
                325                 330                 335     


Lys Tyr Leu Ile Asp Asn Ser Phe Thr Val Ser Ser Gly Ala Arg Pro 
            340                 345                 350         


Gly Ala Gln Lys Val Gly Ile Val Phe Thr Asp Gly Arg Ser Gln Asp 
        355                 360                 365             


Tyr Ile Asn Asp Ala Ala Lys Lys Ala Lys Asp Leu Gly Phe Lys Met 
    370                 375                 380                 


Phe Ala Val Gly Val Gly Asn Ala Val Glu Asp Glu Leu Arg Glu Ile 
385                 390                 395                 400 


Ala Ser Glu Pro Val Ala Glu His Tyr Phe Tyr Thr Ala Asp Phe Lys 
                405                 410                 415     


Thr Ile Asn Gln Ile Gly Lys Lys Leu Gln Lys Lys Ile Cys Val Glu 
            420                 425                 430         


Glu Asp Pro Cys Ala Cys Glu Ser Leu Val Lys Phe Gln Ala Lys Val 
        435                 440                 445             


Glu Gly Leu Leu Gln Ala Leu Thr Arg Lys Leu Glu Ala Val Ser Lys 
    450                 455                 460                 


Arg Leu Ala Ile Leu Glu Asn Thr Val Val 
465                 470                 


<210>  923
<211>  914
<212>  PRT
<213>  Homo Sapiens

<400>  923

Arg Glu Arg Ser Arg Gly Arg Ser Ile Ser Arg Gly Arg His Ala Arg 
1               5                   10                  15      


Thr His Pro Gln Thr Ala Leu Leu Glu Ser Ser Cys Glu Asn Lys Arg 
            20                  25                  30          


Ala Asp Leu Val Phe Ile Ile Asp Ser Ser Arg Ser Val Asn Thr His 
        35                  40                  45              


Asp Tyr Ala Lys Val Lys Glu Phe Ile Val Asp Ile Leu Gln Phe Leu 
    50                  55                  60                  


Asp Ile Gly Pro Asp Val Thr Arg Val Gly Leu Leu Gln Tyr Gly Ser 
65                  70                  75                  80  


Thr Val Lys Asn Glu Phe Ser Leu Lys Thr Phe Lys Arg Lys Ser Glu 
                85                  90                  95      


Val Glu Arg Ala Val Lys Arg Met Arg His Leu Ser Thr Gly Thr Met 
            100                 105                 110         


Thr Gly Leu Ala Ile Gln Tyr Ala Leu Asn Ile Ala Phe Ser Glu Ala 
        115                 120                 125             


Glu Gly Ala Arg Pro Leu Arg Glu Asn Val Pro Arg Val Ile Met Ile 
    130                 135                 140                 


Val Thr Asp Gly Arg Pro Gln Asp Ser Val Ala Glu Val Ala Ala Lys 
145                 150                 155                 160 


Ala Arg Asp Thr Gly Ile Leu Ile Phe Ala Ile Gly Val Gly Gln Val 
                165                 170                 175     


Asp Phe Asn Thr Leu Lys Ser Ile Gly Ser Glu Pro His Glu Asp His 
            180                 185                 190         


Val Phe Leu Val Ala Asn Phe Ser Gln Ile Glu Thr Leu Thr Ser Val 
        195                 200                 205             


Phe Gln Lys Lys Leu Cys Thr Ala His Met Cys Ser Thr Leu Glu His 
    210                 215                 220                 


Asn Cys Ala His Phe Cys Ile Asn Ile Pro Gly Ser Tyr Val Cys Arg 
225                 230                 235                 240 


Cys Lys Gln Gly Tyr Ile Leu Asn Ser Asp Gln Thr Thr Cys Arg Ile 
                245                 250                 255     


Gln Asp Leu Cys Ala Met Glu Asp His Asn Cys Glu Gln Leu Cys Val 
            260                 265                 270         


Asn Val Pro Gly Ser Phe Val Cys Gln Cys Tyr Ser Gly Tyr Ala Leu 
        275                 280                 285             


Ala Glu Asp Gly Lys Arg Cys Val Ala Val Asp Tyr Cys Ala Ser Glu 
    290                 295                 300                 


Asn His Gly Cys Glu His Glu Cys Val Asn Ala Asp Gly Ser Tyr Leu 
305                 310                 315                 320 


Cys Gln Cys His Glu Gly Phe Ala Leu Asn Pro Asp Glu Lys Thr Cys 
                325                 330                 335     


Thr Lys Ile Asp Tyr Cys Ala Ser Ser Asn His Gly Cys Gln His Glu 
            340                 345                 350         


Cys Val Asn Thr Asp Asp Ser Tyr Ser Cys His Cys Leu Lys Gly Phe 
        355                 360                 365             


Thr Leu Asn Pro Asp Lys Lys Thr Cys Arg Arg Ile Asn Tyr Cys Ala 
    370                 375                 380                 


Leu Asn Lys Pro Gly Cys Glu His Glu Cys Val Asn Met Glu Glu Ser 
385                 390                 395                 400 


Tyr Tyr Cys Arg Cys His Arg Gly Tyr Thr Leu Asp Pro Asn Gly Lys 
                405                 410                 415     


Thr Cys Ser Arg Val Asp His Cys Ala Gln Gln Asp His Gly Cys Glu 
            420                 425                 430         


Gln Leu Cys Leu Asn Thr Glu Asp Ser Phe Val Cys Gln Cys Ser Glu 
        435                 440                 445             


Gly Phe Leu Ile Asn Glu Asp Leu Lys Thr Cys Ser Arg Val Asp Tyr 
    450                 455                 460                 


Cys Leu Leu Ser Asp His Gly Cys Glu Tyr Ser Cys Val Asn Met Asp 
465                 470                 475                 480 


Arg Ser Phe Ala Cys Gln Cys Pro Glu Gly His Val Leu Arg Ser Asp 
                485                 490                 495     


Gly Lys Thr Cys Ala Lys Leu Asp Ser Cys Ala Leu Gly Asp His Gly 
            500                 505                 510         


Cys Glu His Ser Cys Val Ser Ser Glu Asp Ser Phe Val Cys Gln Cys 
        515                 520                 525             


Phe Glu Gly Tyr Ile Leu Arg Glu Asp Gly Lys Thr Cys Arg Arg Lys 
    530                 535                 540                 


Asp Val Cys Gln Ala Ile Asp His Gly Cys Glu His Ile Cys Val Asn 
545                 550                 555                 560 


Ser Asp Asp Ser Tyr Thr Cys Glu Cys Leu Glu Gly Phe Arg Leu Ala 
                565                 570                 575     


Glu Asp Gly Lys Arg Cys Arg Arg Lys Asp Val Cys Lys Ser Thr His 
            580                 585                 590         


His Gly Cys Glu His Ile Cys Val Asn Asn Gly Asn Ser Tyr Ile Cys 
        595                 600                 605             


Lys Cys Ser Glu Gly Phe Val Leu Ala Glu Asp Gly Arg Arg Cys Lys 
    610                 615                 620                 


Lys Cys Thr Glu Gly Pro Ile Asp Leu Val Phe Val Ile Asp Gly Ser 
625                 630                 635                 640 


Lys Ser Leu Gly Glu Glu Asn Phe Glu Val Val Lys Gln Phe Val Thr 
                645                 650                 655     


Gly Ile Ile Asp Ser Leu Thr Ile Ser Pro Lys Ala Ala Arg Val Gly 
            660                 665                 670         


Leu Leu Gln Tyr Ser Thr Gln Val His Thr Glu Phe Thr Leu Arg Asn 
        675                 680                 685             


Phe Asn Ser Ala Lys Asp Met Lys Lys Ala Val Ala His Met Lys Tyr 
    690                 695                 700                 


Met Gly Lys Gly Ser Met Thr Gly Leu Ala Leu Lys His Met Phe Glu 
705                 710                 715                 720 


Arg Ser Phe Thr Gln Gly Glu Gly Ala Arg Pro Leu Ser Thr Arg Val 
                725                 730                 735     


Pro Arg Ala Ala Ile Val Phe Thr Asp Gly Arg Ala Gln Asp Asp Val 
            740                 745                 750         


Ser Glu Trp Ala Ser Lys Ala Lys Ala Asn Gly Ile Thr Met Tyr Ala 
        755                 760                 765             


Val Gly Val Gly Lys Ala Ile Glu Glu Glu Leu Gln Glu Ile Ala Ser 
    770                 775                 780                 


Glu Pro Thr Asn Lys His Leu Phe Tyr Ala Glu Asp Phe Ser Thr Met 
785                 790                 795                 800 


Asp Glu Ile Ser Glu Lys Leu Lys Lys Gly Ile Cys Glu Ala Leu Glu 
                805                 810                 815     


Asp Ser Asp Gly Arg Gln Asp Ser Pro Ala Gly Glu Leu Pro Lys Thr 
            820                 825                 830         


Val Gln Gln Pro Thr Val Gln His Arg Tyr Leu Phe Glu Glu Asp Asn 
        835                 840                 845             


Leu Leu Arg Ser Thr Gln Lys Leu Ser His Ser Thr Lys Pro Ser Gly 
    850                 855                 860                 


Ser Pro Leu Glu Glu Lys His Asp Gln Cys Lys Cys Glu Asn Leu Ile 
865                 870                 875                 880 


Met Phe Gln Asn Leu Ala Asn Glu Glu Val Arg Lys Leu Thr Gln Arg 
                885                 890                 895     


Leu Glu Glu Met Thr Gln Arg Met Glu Ala Leu Glu Asn Arg Leu Arg 
            900                 905                 910         


Tyr Arg 
        


<210>  924
<211>  458
<212>  PRT
<213>  Homo Sapiens

<400>  924

Asp Pro Val Ala Arg Pro Gly Phe Arg Arg Leu Glu Thr Arg Gly Pro 
1               5                   10                  15      


Gly Gly Ser Pro Gly Arg Arg Pro Ser Pro Ala Ala Pro Asp Gly Ala 
            20                  25                  30          


Pro Ala Ser Gly Thr Ser Glu Pro Gly Arg Ala Arg Gly Ala Gly Val 
        35                  40                  45              


Cys Lys Ser Arg Pro Leu Asp Leu Val Phe Ile Ile Asp Ser Ser Arg 
    50                  55                  60                  


Ser Val Arg Pro Leu Glu Phe Thr Lys Val Lys Thr Phe Val Ser Arg 
65                  70                  75                  80  


Ile Ile Asp Thr Leu Asp Ile Gly Pro Ala Asp Thr Arg Val Ala Val 
                85                  90                  95      


Val Asn Tyr Ala Ser Thr Val Lys Ile Glu Phe Gln Leu Gln Ala Tyr 
            100                 105                 110         


Thr Asp Lys Gln Ser Leu Lys Gln Ala Val Gly Arg Ile Thr Pro Leu 
        115                 120                 125             


Ser Thr Gly Thr Met Ser Gly Leu Ala Ile Gln Thr Ala Met Asp Glu 
    130                 135                 140                 


Ala Phe Thr Val Glu Ala Gly Ala Arg Glu Pro Ser Ser Asn Ile Pro 
145                 150                 155                 160 


Lys Val Ala Ile Ile Val Thr Asp Gly Arg Pro Gln Asp Gln Val Asn 
                165                 170                 175     


Glu Val Ala Ala Arg Ala Gln Ala Ser Gly Ile Glu Leu Tyr Ala Val 
            180                 185                 190         


Gly Val Asp Arg Ala Asp Met Ala Ser Leu Lys Met Met Ala Ser Glu 
        195                 200                 205             


Pro Leu Glu Glu His Val Phe Tyr Val Glu Thr Tyr Gly Val Ile Glu 
    210                 215                 220                 


Lys Leu Ser Ser Arg Phe Gln Glu Thr Phe Cys Ala Leu Asp Pro Cys 
225                 230                 235                 240 


Val Leu Gly Thr His Gln Cys Gln His Val Cys Ile Ser Asp Gly Glu 
                245                 250                 255     


Gly Lys His His Cys Glu Cys Ser Gln Gly Tyr Thr Leu Asn Ala Asp 
            260                 265                 270         


Lys Lys Thr Cys Ser Ala Leu Asp Arg Cys Ala Leu Asn Thr His Gly 
        275                 280                 285             


Cys Glu His Ile Cys Val Asn Asp Arg Ser Gly Ser Tyr His Cys Glu 
    290                 295                 300                 


Cys Tyr Glu Gly Tyr Thr Leu Asn Glu Asp Arg Lys Thr Cys Ser Ala 
305                 310                 315                 320 


Gln Asp Lys Cys Ala Leu Gly Thr His Gly Cys Gln His Ile Cys Val 
                325                 330                 335     


Asn Asp Arg Thr Gly Ser His His Cys Glu Cys Tyr Glu Gly Tyr Thr 
            340                 345                 350         


Leu Asn Ala Asp Lys Lys Thr Cys Ser Val Arg Asp Lys Cys Ala Leu 
        355                 360                 365             


Gly Ser His Gly Cys Gln His Ile Cys Val Ser Asp Gly Ala Ala Ser 
    370                 375                 380                 


Tyr His Cys Asp Cys Tyr Pro Gly Tyr Thr Leu Asn Glu Asp Lys Lys 
385                 390                 395                 400 


Thr Cys Ser Ala Thr Glu Glu Ala Arg Arg Leu Val Ser Thr Glu Asp 
                405                 410                 415     


Ala Cys Gly Cys Glu Ala Thr Leu Ala Phe Gln Asp Lys Val Ser Ser 
            420                 425                 430         


Tyr Leu Gln Arg Leu Asn Thr Lys Leu Asp Asp Ile Leu Glu Lys Leu 
        435                 440                 445             


Lys Ile Asn Glu Tyr Gly Gln Ile His Arg 
    450                 455             


<210>  925
<211>  563
<212>  PRT
<213>  Homo Sapiens

<400>  925

Thr Gln Leu Gln Leu Thr Gly Pro Arg Cys His Thr Gly Pro Leu Asp 
1               5                   10                  15      


Leu Val Phe Val Ile Asp Ser Ser Arg Ser Val Arg Pro Phe Glu Phe 
            20                  25                  30          


Glu Thr Met Arg Gln Phe Leu Met Gly Leu Leu Arg Gly Leu Asn Val 
        35                  40                  45              


Gly Pro Asn Ala Thr Arg Val Gly Val Ile Gln Tyr Ser Ser Gln Val 
    50                  55                  60                  


Gln Ser Val Phe Pro Leu Arg Ala Phe Ser Arg Arg Glu Asp Met Glu 
65                  70                  75                  80  


Arg Ala Ile Arg Asp Leu Val Pro Leu Ala Gln Gly Thr Met Thr Gly 
                85                  90                  95      


Leu Ala Ile Gln Tyr Ala Met Asn Val Ala Phe Ser Val Ala Glu Gly 
            100                 105                 110         


Ala Arg Pro Pro Glu Glu Arg Val Pro Arg Val Ala Val Ile Val Thr 
        115                 120                 125             


Asp Gly Arg Pro Gln Asp Arg Val Ala Glu Val Ala Ala Gln Ala Arg 
    130                 135                 140                 


Ala Ser Gly Ile Glu Ile Tyr Ala Val Gly Val Gln Arg Ala Asp Val 
145                 150                 155                 160 


Gly Ser Leu Arg Ala Met Ala Ser Pro Pro Leu Asp Glu His Val Phe 
                165                 170                 175     


Leu Val Glu Ser Phe Asp Leu Ile Gln Glu Phe Gly Leu Gln Phe Gln 
            180                 185                 190         


Ser Arg Leu Cys Ala Ile Asp Leu Cys Ala Glu Gly Thr His Gly Cys 
        195                 200                 205             


Glu His His Cys Val Asn Ser Pro Gly Ser Tyr Phe Cys His Cys Gln 
    210                 215                 220                 


Val Gly Phe Val Leu Gln Gln Asp Gln Arg Ser Cys Arg Ala Ile Asp 
225                 230                 235                 240 


Tyr Cys Ser Phe Gly Asn His Ser Cys Gln His Glu Cys Val Ser Thr 
                245                 250                 255     


Pro Gly Gly Pro Arg Cys His Cys Arg Glu Gly His Asp Leu Gln Pro 
            260                 265                 270         


Asp Gly Arg Ser Cys Gln Val Arg Asp Leu Cys Asn Gly Val Asp His 
        275                 280                 285             


Gly Cys Glu Phe Gln Cys Val Ser Glu Gly Leu Ser Tyr Arg Cys Leu 
    290                 295                 300                 


Cys Pro Glu Gly Arg Gln Leu Gln Ala Asp Gly Lys Ser Cys Asn Arg 
305                 310                 315                 320 


Cys Arg Glu Gly His Val Asp Leu Val Leu Leu Val Asp Gly Ser Lys 
                325                 330                 335     


Ser Val Arg Pro Gln Asn Phe Glu Leu Val Lys Arg Phe Val Asn Gln 
            340                 345                 350         


Ile Val Asp Phe Leu Asp Val Ser Pro Glu Gly Thr Arg Val Gly Leu 
        355                 360                 365             


Val Gln Phe Ser Ser Arg Val Arg Thr Glu Phe Pro Leu Gly Arg Tyr 
    370                 375                 380                 


Gly Thr Ala Ala Glu Val Lys Gln Ala Val Leu Ala Val Glu Tyr Met 
385                 390                 395                 400 


Glu Arg Gly Thr Met Thr Gly Leu Ala Leu Arg His Met Val Glu His 
                405                 410                 415     


Ser Phe Ser Glu Ala Gln Gly Ala Arg Pro Arg Ala Leu Asn Val Pro 
            420                 425                 430         


Arg Val Gly Leu Val Phe Thr Asp Gly Arg Ser Gln Asp Asp Ile Ser 
        435                 440                 445             


Val Trp Ala Ala Arg Ala Lys Glu Glu Gly Ile Val Met Tyr Ala Val 
    450                 455                 460                 


Gly Val Gly Lys Ala Val Glu Ala Glu Leu Arg Glu Ile Ala Ser Glu 
465                 470                 475                 480 


Pro Ala Glu Leu His Val Ser Tyr Ala Pro Asp Phe Gly Thr Met Thr 
                485                 490                 495     


His Leu Leu Glu Asn Leu Arg Gly Ser Ile Cys Pro Glu Glu Gly Ile 
            500                 505                 510         


Ser Ala Gly Thr Glu Leu Arg Ser Pro Cys Glu Cys Glu Ser Leu Val 
        515                 520                 525             


Glu Phe Gln Gly Arg Thr Leu Gly Ala Leu Glu Ser Leu Thr Leu Asn 
    530                 535                 540                 


Leu Ala Gln Leu Thr Ala Arg Leu Glu Asp Leu Glu Asn Gln Leu Ala 
545                 550                 555                 560 


Asn Gln Lys 
            


<210>  926
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  926

Glu Thr Val Thr Cys Glu Asp Ala Gln Lys Thr Cys Pro Ala Val Ile 
1               5                   10                  15      


Ala Cys Ser Ser Pro Gly Ile Asn Gly Phe Pro Gly Lys Asp Gly Arg 
            20                  25                  30          


Asp Gly Thr Lys Gly Glu Lys Gly Glu Pro Gly Gln Gly Leu Arg Gly 
        35                  40                  45              


Leu Gln Gly Pro Pro Gly Lys Leu Gly Pro Pro Gly Asn Pro Gly Pro 
    50                  55                  60                  


Ser Gly Ser Pro Gly Pro Lys Gly Gln Lys Gly Asp Pro Gly Lys Ser 
65                  70                  75                  80  


Pro Asp Gly Asp Ser Ser Leu Ala Ala Ser Glu Arg Lys Ala Leu Gln 
                85                  90                  95      


Thr Glu Met Ala Arg Ile Lys Lys Trp Leu Thr Phe Ser Leu Gly Lys 
            100                 105                 110         


Gln Val Gly Asn Lys Phe Phe Leu Thr Asn Gly Glu Ile Met Thr Phe 
        115                 120                 125             


Glu Lys Val Lys Ala Leu Cys Val Lys Phe Gln Ala Ser Val Ala Thr 
    130                 135                 140                 


Pro Arg Asn Ala Ala Glu Asn Gly Ala Ile Gln Asn Leu Ile Lys Glu 
145                 150                 155                 160 


Glu Ala Phe Leu Gly Ile Thr Asp Glu Lys Thr Glu Gly Gln Phe Val 
                165                 170                 175     


Asp Leu Thr Gly Asn Arg Leu Thr Tyr Thr Asn Trp Asn Glu Gly Glu 
            180                 185                 190         


Pro Asn Asn Ala Gly Ser Asp Glu Asp Cys Val Leu Leu Leu Lys Asn 
        195                 200                 205             


Gly Gln Trp Asn Asp Val Pro Cys Ser Thr Ser His Leu Ala Val Cys 
    210                 215                 220                 


Glu Phe Pro Ile 
225             


<210>  927
<211>  536
<212>  PRT
<213>  Homo Sapiens

<400>  927

Val Pro Gly Glu Ala Glu Gln Pro Ala Pro Glu Leu Val Glu Val Glu 
1               5                   10                  15      


Val Gly Ser Thr Ala Leu Leu Lys Cys Gly Leu Ser Gln Ser Gln Gly 
            20                  25                  30          


Asn Leu Ser His Val Asp Trp Phe Ser Val His Lys Glu Lys Arg Thr 
        35                  40                  45              


Leu Ile Phe Arg Val Arg Gln Gly Gln Gly Gln Ser Glu Pro Gly Glu 
    50                  55                  60                  


Tyr Glu Gln Arg Leu Ser Leu Gln Asp Arg Gly Ala Thr Leu Ala Leu 
65                  70                  75                  80  


Thr Gln Val Thr Pro Gln Asp Glu Arg Ile Phe Leu Cys Gln Gly Lys 
                85                  90                  95      


Arg Pro Arg Ser Gln Glu Tyr Arg Ile Gln Leu Arg Val Tyr Lys Ala 
            100                 105                 110         


Pro Glu Glu Pro Asn Ile Gln Val Asn Pro Leu Gly Ile Pro Val Asn 
        115                 120                 125             


Ser Lys Glu Pro Glu Glu Val Ala Thr Cys Val Gly Arg Asn Gly Tyr 
    130                 135                 140                 


Pro Ile Pro Gln Val Ile Trp Tyr Lys Asn Gly Arg Pro Leu Lys Glu 
145                 150                 155                 160 


Glu Lys Asn Arg Val His Ile Gln Ser Ser Gln Thr Val Glu Ser Ser 
                165                 170                 175     


Gly Leu Tyr Thr Leu Gln Ser Ile Leu Lys Ala Gln Leu Val Lys Glu 
            180                 185                 190         


Asp Lys Asp Ala Gln Phe Tyr Cys Glu Leu Asn Tyr Arg Leu Pro Ser 
        195                 200                 205             


Gly Asn His Met Lys Glu Ser Arg Glu Val Thr Val Pro Val Phe Tyr 
    210                 215                 220                 


Pro Thr Glu Lys Val Trp Leu Glu Val Glu Pro Val Gly Met Leu Lys 
225                 230                 235                 240 


Glu Gly Asp Arg Val Glu Ile Arg Cys Leu Ala Asp Gly Asn Pro Pro 
                245                 250                 255     


Pro His Phe Ser Ile Ser Lys Gln Asn Pro Ser Thr Arg Glu Ala Glu 
            260                 265                 270         


Glu Glu Thr Thr Asn Asp Asn Gly Val Leu Val Leu Glu Pro Ala Arg 
        275                 280                 285             


Lys Glu His Ser Gly Arg Tyr Glu Cys Gln Gly Leu Asp Leu Asp Thr 
    290                 295                 300                 


Met Ile Ser Leu Leu Ser Glu Pro Gln Glu Leu Leu Val Asn Tyr Val 
305                 310                 315                 320 


Ser Asp Val Arg Val Ser Pro Ala Ala Pro Glu Arg Gln Glu Gly Ser 
                325                 330                 335     


Ser Leu Thr Leu Thr Cys Glu Ala Glu Ser Ser Gln Asp Leu Glu Phe 
            340                 345                 350         


Gln Trp Leu Arg Glu Glu Thr Gly Gln Val Leu Glu Arg Gly Pro Val 
        355                 360                 365             


Leu Gln Leu His Asp Leu Lys Arg Glu Ala Gly Gly Gly Tyr Arg Cys 
    370                 375                 380                 


Val Ala Ser Val Pro Ser Ile Pro Gly Leu Asn Arg Thr Gln Leu Val 
385                 390                 395                 400 


Asn Val Ala Ile Phe Gly Pro Pro Trp Met Ala Phe Lys Glu Arg Lys 
                405                 410                 415     


Val Trp Val Lys Glu Asn Met Val Leu Asn Leu Ser Cys Glu Ala Ser 
            420                 425                 430         


Gly His Pro Arg Pro Thr Ile Ser Trp Asn Val Asn Gly Thr Ala Ser 
        435                 440                 445             


Glu Gln Asp Gln Asp Pro Gln Arg Val Leu Ser Thr Leu Asn Val Leu 
    450                 455                 460                 


Val Thr Pro Glu Leu Leu Glu Thr Gly Val Glu Cys Thr Ala Ser Asn 
465                 470                 475                 480 


Asp Leu Gly Lys Asn Thr Ser Ile Leu Phe Leu Glu Leu Val Asn Leu 
                485                 490                 495     


Thr Thr Leu Thr Pro Asp Ser Asn Thr Thr Thr Gly Leu Ser Thr Ser 
            500                 505                 510         


Thr Ala Ser Pro His Thr Arg Ala Asn Ser Thr Ser Thr Glu Arg Lys 
        515                 520                 525             


Leu Pro Glu Pro Glu Ser Arg Gly 
    530                 535     


<210>  928
<211>  294
<212>  PRT
<213>  Homo Sapiens

<400>  928

Cys Glu Glu Pro Pro Thr Phe Glu Ala Met Glu Leu Ile Gly Lys Pro 
1               5                   10                  15      


Lys Pro Tyr Tyr Glu Ile Gly Glu Arg Val Asp Tyr Lys Cys Lys Lys 
            20                  25                  30          


Gly Tyr Phe Tyr Ile Pro Pro Leu Ala Thr His Thr Ile Cys Asp Arg 
        35                  40                  45              


Asn His Thr Trp Leu Pro Val Ser Asp Asp Ala Cys Tyr Arg Glu Thr 
    50                  55                  60                  


Cys Pro Tyr Ile Arg Asp Pro Leu Asn Gly Gln Ala Val Pro Ala Asn 
65                  70                  75                  80  


Gly Thr Tyr Glu Phe Gly Tyr Gln Met His Phe Ile Cys Asn Glu Gly 
                85                  90                  95      


Tyr Tyr Leu Ile Gly Glu Glu Ile Leu Tyr Cys Glu Leu Lys Gly Ser 
            100                 105                 110         


Val Ala Ile Trp Ser Gly Lys Pro Pro Ile Cys Glu Lys Val Leu Cys 
        115                 120                 125             


Thr Pro Pro Pro Lys Ile Lys Asn Gly Lys His Thr Phe Ser Glu Val 
    130                 135                 140                 


Glu Val Phe Glu Tyr Leu Asp Ala Val Thr Tyr Ser Cys Asp Pro Ala 
145                 150                 155                 160 


Pro Gly Pro Asp Pro Phe Ser Leu Ile Gly Glu Ser Thr Ile Tyr Cys 
                165                 170                 175     


Gly Asp Asn Ser Val Trp Ser Arg Ala Ala Pro Glu Cys Lys Val Val 
            180                 185                 190         


Lys Cys Arg Phe Pro Val Val Glu Asn Gly Lys Gln Ile Ser Gly Phe 
        195                 200                 205             


Gly Lys Lys Phe Tyr Tyr Lys Ala Thr Val Met Phe Glu Cys Asp Lys 
    210                 215                 220                 


Gly Phe Tyr Leu Asp Gly Ser Asp Thr Ile Val Cys Asp Ser Asn Ser 
225                 230                 235                 240 


Thr Trp Asp Pro Pro Val Pro Lys Cys Leu Lys Val Ser Thr Ser Ser 
                245                 250                 255     


Thr Thr Lys Ser Pro Ala Ser Ser Ala Ser Gly Pro Arg Pro Thr Tyr 
            260                 265                 270         


Lys Pro Pro Val Ser Asn Tyr Pro Gly Tyr Pro Lys Pro Glu Glu Gly 
        275                 280                 285             


Ile Leu Asp Ser Leu Asp 
    290                 


<210>  929
<211>  914
<212>  PRT
<213>  Homo Sapiens

<400>  929

Gln Gly Val Tyr Ala Pro Ala Gln Ala Gln Ile Val His Ala Gly Gln 
1               5                   10                  15      


Ala Cys Val Val Lys Glu Asp Asn Ile Ser Glu Arg Val Tyr Thr Ile 
            20                  25                  30          


Arg Glu Gly Asp Thr Leu Met Leu Gln Cys Leu Val Thr Gly His Pro 
        35                  40                  45              


Arg Pro Gln Val Arg Trp Thr Lys Thr Ala Gly Ser Ala Ser Asp Lys 
    50                  55                  60                  


Phe Gln Glu Thr Ser Val Phe Asn Glu Thr Leu Arg Ile Glu Arg Ile 
65                  70                  75                  80  


Ala Arg Thr Gln Gly Gly Arg Tyr Tyr Cys Lys Ala Glu Asn Gly Val 
                85                  90                  95      


Gly Val Pro Ala Ile Lys Ser Ile Arg Val Asp Val Gln Tyr Leu Asp 
            100                 105                 110         


Glu Pro Met Leu Thr Val His Gln Thr Val Ser Asp Val Arg Gly Asn 
        115                 120                 125             


Phe Tyr Gln Glu Lys Thr Val Phe Leu Arg Cys Thr Val Asn Ser Asn 
    130                 135                 140                 


Pro Pro Ala Arg Phe Ile Trp Lys Arg Gly Ser Asp Thr Leu Ser His 
145                 150                 155                 160 


Ser Gln Asp Asn Gly Val Asp Ile Tyr Glu Pro Leu Tyr Thr Gln Gly 
                165                 170                 175     


Glu Thr Lys Val Leu Lys Leu Lys Asn Leu Arg Pro Gln Asp Tyr Ala 
            180                 185                 190         


Ser Tyr Thr Cys Gln Val Ser Val Arg Asn Val Cys Gly Ile Pro Asp 
        195                 200                 205             


Lys Ala Ile Thr Phe Arg Leu Thr Asn Thr Thr Ala Pro Pro Ala Leu 
    210                 215                 220                 


Lys Leu Ser Val Asn Glu Thr Leu Val Val Asn Pro Gly Glu Asn Val 
225                 230                 235                 240 


Thr Val Gln Cys Leu Leu Thr Gly Gly Asp Pro Leu Pro Gln Leu Gln 
                245                 250                 255     


Trp Ser His Gly Pro Gly Pro Leu Pro Leu Gly Ala Leu Ala Gln Gly 
            260                 265                 270         


Gly Thr Leu Ser Ile Pro Ser Val Gln Ala Arg Asp Ser Gly Tyr Tyr 
        275                 280                 285             


Asn Cys Thr Ala Thr Asn Asn Val Gly Asn Pro Ala Lys Lys Thr Val 
    290                 295                 300                 


Asn Leu Leu Val Arg Ser Met Lys Asn Ala Thr Phe Gln Ile Thr Pro 
305                 310                 315                 320 


Asp Val Ile Lys Glu Ser Glu Asn Ile Gln Leu Gly Gln Asp Leu Lys 
                325                 330                 335     


Leu Ser Cys His Val Asp Ala Val Pro Gln Glu Lys Val Thr Tyr Gln 
            340                 345                 350         


Trp Phe Lys Asn Gly Lys Pro Ala Arg Met Ser Lys Arg Leu Leu Val 
        355                 360                 365             


Thr Arg Asn Asp Pro Glu Leu Pro Ala Val Thr Ser Ser Leu Glu Leu 
    370                 375                 380                 


Ile Asp Leu His Phe Ser Asp Tyr Gly Thr Tyr Leu Cys Met Ala Ser 
385                 390                 395                 400 


Phe Pro Gly Ala Pro Val Pro Asp Leu Ser Val Glu Val Asn Ile Ser 
                405                 410                 415     


Ser Glu Thr Val Pro Pro Thr Ile Ser Val Pro Lys Gly Arg Ala Val 
            420                 425                 430         


Val Thr Val Arg Glu Gly Ser Pro Ala Glu Leu Gln Cys Glu Val Arg 
        435                 440                 445             


Gly Lys Pro Arg Pro Pro Val Leu Trp Ser Arg Val Asp Lys Glu Ala 
    450                 455                 460                 


Ala Leu Leu Pro Ser Gly Leu Pro Leu Glu Glu Thr Pro Asp Gly Lys 
465                 470                 475                 480 


Leu Arg Leu Glu Arg Val Ser Arg Asp Met Ser Gly Thr Tyr Arg Cys 
                485                 490                 495     


Gln Thr Ala Arg Tyr Asn Gly Phe Asn Val Arg Pro Arg Glu Ala Gln 
            500                 505                 510         


Val Gln Leu Asn Val Gln Phe Pro Pro Glu Val Glu Pro Ser Ser Gln 
        515                 520                 525             


Asp Val Arg Gln Ala Leu Gly Arg Pro Val Leu Leu Arg Cys Ser Leu 
    530                 535                 540                 


Leu Arg Gly Ser Pro Gln Arg Ile Ala Ser Ala Val Trp Arg Phe Lys 
545                 550                 555                 560 


Gly Gln Leu Leu Pro Pro Pro Pro Val Val Pro Ala Ala Ala Glu Ala 
                565                 570                 575     


Pro Asp His Ala Glu Leu Arg Leu Asp Ala Val Thr Arg Asp Ser Ser 
            580                 585                 590         


Gly Ser Tyr Glu Cys Ser Val Ser Asn Asp Val Gly Ser Ala Ala Cys 
        595                 600                 605             


Leu Phe Gln Val Ser Ala Lys Ala Tyr Ser Pro Glu Phe Tyr Phe Asp 
    610                 615                 620                 


Thr Pro Asn Pro Thr Arg Ser His Lys Leu Ser Lys Asn Tyr Ser Tyr 
625                 630                 635                 640 


Val Leu Gln Trp Thr Gln Arg Glu Pro Asp Ala Val Asp Pro Val Leu 
                645                 650                 655     


Asn Tyr Arg Leu Ser Ile Arg Gln Leu Asn Gln His Asn Ala Val Val 
            660                 665                 670         


Lys Ala Ile Pro Val Arg Arg Val Glu Lys Gly Gln Leu Leu Glu Tyr 
        675                 680                 685             


Ile Leu Thr Asp Leu Arg Val Pro His Ser Tyr Glu Val Arg Leu Thr 
    690                 695                 700                 


Pro Tyr Thr Thr Phe Gly Ala Gly Asp Met Ala Ser Arg Ile Ile His 
705                 710                 715                 720 


Tyr Thr Glu Pro Ile Asn Ser Pro Asn Leu Ser Asp Asn Thr Cys His 
                725                 730                 735     


Phe Glu Asp Glu Lys Ile Cys Gly Tyr Thr Gln Asp Leu Thr Asp Asn 
            740                 745                 750         


Phe Asp Trp Thr Arg Gln Asn Ala Leu Thr Gln Asn Pro Lys Arg Ser 
        755                 760                 765             


Pro Asn Thr Gly Pro Pro Thr Asp Ile Ser Gly Thr Pro Glu Gly Tyr 
    770                 775                 780                 


Tyr Met Phe Ile Glu Thr Ser Arg Pro Arg Glu Leu Gly Asp Arg Ala 
785                 790                 795                 800 


Arg Leu Val Ser Pro Leu Tyr Asn Ala Ser Ala Lys Phe Tyr Cys Val 
                805                 810                 815     


Ser Phe Phe Tyr His Met Tyr Gly Lys His Ile Gly Ser Leu Asn Leu 
            820                 825                 830         


Leu Val Arg Ser Arg Asn Lys Gly Ala Leu Asp Thr His Ala Trp Ser 
        835                 840                 845             


Leu Ser Gly Asn Lys Gly Asn Val Trp Gln Gln Ala His Val Pro Ile 
    850                 855                 860                 


Ser Pro Ser Gly Pro Phe Gln Ile Ile Phe Glu Gly Val Arg Gly Pro 
865                 870                 875                 880 


Gly Tyr Leu Gly Asp Ile Ala Ile Asp Asp Val Thr Leu Lys Lys Gly 
                885                 890                 895     


Glu Cys Pro Arg Lys Gln Thr Asp Pro Asn Lys Val Val Val Met Pro 
            900                 905                 910         


Gly Ser 
        


<210>  930
<211>  303
<212>  PRT
<213>  Homo Sapiens

<400>  930

Pro Val Val Thr Val His Gln Ser Ile Gly Glu Ala Lys Glu Gln Phe 
1               5                   10                  15      


Tyr Tyr Glu Arg Thr Val Phe Leu Arg Cys Val Ala Asn Ser Asn Pro 
            20                  25                  30          


Pro Val Arg Tyr Ser Trp Arg Arg Gly Gln Glu Val Leu Leu Gln Gly 
        35                  40                  45              


Ser Asp Lys Gly Val Glu Ile Tyr Glu Pro Phe Phe Thr Gln Gly Glu 
    50                  55                  60                  


Thr Lys Ile Leu Lys Leu Lys Asn Leu Arg Pro Gln Asp Tyr Ala Asn 
65                  70                  75                  80  


Tyr Ser Cys Ile Ala Ser Val Arg Asn Val Cys Asn Ile Pro Asp Lys 
                85                  90                  95      


Met Val Ser Phe Arg Leu Ser Asn Lys Thr Ala Ser Pro Ser Ile Lys 
            100                 105                 110         


Leu Leu Val Asp Asp Pro Ile Val Val Asn Pro Gly Glu Ala Ile Thr 
        115                 120                 125             


Leu Val Cys Val Thr Thr Gly Gly Glu Pro Ala Pro Ser Leu Thr Trp 
    130                 135                 140                 


Val Arg Ser Phe Gly Thr Leu Pro Glu Lys Thr Val Leu Asn Gly Gly 
145                 150                 155                 160 


Thr Leu Thr Ile Pro Ala Ile Thr Ser Asp Asp Ala Gly Thr Tyr Ser 
                165                 170                 175     


Cys Ile Ala Asn Asn Asn Val Gly Asn Pro Ala Lys Lys Ser Thr Asn 
            180                 185                 190         


Ile Ile Val Arg Ala Leu Lys Lys Gly Arg Phe Trp Ile Thr Pro Asp 
        195                 200                 205             


Pro Tyr His Lys Asp Asp Asn Ile Gln Ile Gly Arg Glu Val Lys Ile 
    210                 215                 220                 


Ser Cys Gln Val Glu Ala Val Pro Ser Glu Glu Leu Thr Phe Ser Trp 
225                 230                 235                 240 


Phe Lys Asn Gly Arg Pro Leu Arg Ser Ser Glu Arg Met Val Ile Thr 
                245                 250                 255     


Gln Thr Asp Pro Asp Val Ser Pro Gly Thr Thr Asn Leu Asp Ile Ile 
            260                 265                 270         


Asp Leu Lys Phe Thr Asp Phe Gly Thr Tyr Thr Cys Val Ala Ser Leu 
        275                 280                 285             


Lys Gly Gly Gly Ile Ser Asp Ile Ser Ile Asp Val Asn Ile Ser 
    290                 295                 300             


<210>  931
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  931

Leu Asn Leu Glu Asp Pro Asn Val Cys Ser His Trp Glu Ser Tyr Ser 
1               5                   10                  15      


Val Thr Val Gln Glu Ser Tyr Pro His Pro Phe Asp Gln Ile Tyr Tyr 
            20                  25                  30          


Thr Ser Cys Thr Asp Ile Leu Asn Trp Phe Lys Cys Thr Arg His Arg 
        35                  40                  45              


Val Ser Tyr Arg Thr Ala Tyr Arg His Gly Glu Lys Thr Met Tyr Arg 
    50                  55                  60                  


Arg Lys Ser Gln Cys Cys Pro Gly Phe Tyr Glu Ser Gly Glu Met Cys 
65                  70                  75                  80  


Val Pro His Cys Ala Asp Lys Cys Val His Gly Arg Cys Ile Ala Pro 
                85                  90                  95      


Asn Thr Cys Gln Cys Glu Pro Gly Trp Gly Gly Thr Asn Cys Ser Ser 
            100                 105                 110         


Ala Cys Asp Gly Asp His Trp Gly Pro His Cys Thr Ser Arg Cys Gln 
        115                 120                 125             


Cys Lys Asn Gly Ala Leu Cys Asn Pro Ile Thr Gly Ala Cys His Cys 
    130                 135                 140                 


Ala Ala Gly Phe Arg Gly Trp Arg Cys Glu Asp Arg Cys Glu Gln Gly 
145                 150                 155                 160 


Thr Tyr Gly Asn Asp Cys His Gln Arg Cys Gln Cys Gln Asn Gly Ala 
                165                 170                 175     


Thr Cys Asp His Val Thr Gly Glu Cys Arg Cys Pro Pro Gly Tyr Thr 
            180                 185                 190         


Gly Ala Phe Cys Glu Asp Leu Cys Pro Pro Gly Lys His Gly Pro Gln 
        195                 200                 205             


Cys Glu Gln Arg Cys Pro Cys Gln Asn Gly Gly Val Cys His His Val 
    210                 215                 220                 


Thr Gly Glu Cys Ser Cys Pro Ser Gly Trp Met Gly Thr Val Cys Gly 
225                 230                 235                 240 


Gln Pro Cys Pro Glu Gly Arg Phe Gly Lys Asn Cys Ser Gln Glu Cys 
                245                 250                 255     


Gln Cys His Asn Gly Gly Thr Cys Asp Ala Ala Thr Gly Gln Cys His 
            260                 265                 270         


Cys Ser Pro Gly Tyr Thr Gly Glu Arg Cys Gln Asp Glu Cys Pro Val 
        275                 280                 285             


Gly Thr Tyr Gly Val Leu Cys Ala Glu Thr Cys Gln Cys Val Asn Gly 
    290                 295                 300                 


Gly Lys Cys Tyr His Val Ser Gly Ala Cys Leu Cys Glu Ala Gly Phe 
305                 310                 315                 320 


Ala Gly Glu Arg Cys Glu Ala Arg Leu Cys Pro Glu Gly Leu Tyr Gly 
                325                 330                 335     


Ile Lys Cys Asp Lys Arg Cys Pro Cys His Leu Glu Asn Thr His Ser 
            340                 345                 350         


Cys His Pro Met Ser Gly Glu Cys Ala Cys Lys Pro Gly Trp Ser Gly 
        355                 360                 365             


Leu Tyr Cys Asn Glu Thr Cys Ser Pro Gly Phe Tyr Gly Glu Ala Cys 
    370                 375                 380                 


Gln Gln Ile Cys Ser Cys Gln Asn Gly Ala Asp Cys Asp Ser Val Thr 
385                 390                 395                 400 


Gly Lys Cys Thr Cys Ala Pro Gly Phe Lys Gly Ile Asp Cys Ser Thr 
                405                 410                 415     


Pro Cys Pro Leu Gly Thr Tyr Gly Ile Asn Cys Ser Ser Arg Cys Gly 
            420                 425                 430         


Cys Lys Asn Asp Ala Val Cys Ser Pro Val Asp Gly Ser Cys Thr Cys 
        435                 440                 445             


Lys Ala Gly Trp His Gly Val Asp Cys Ser Ile Arg Cys Pro Ser Gly 
    450                 455                 460                 


Thr Trp Gly Phe Gly Cys Asn Leu Thr Cys Gln Cys Leu Asn Gly Gly 
465                 470                 475                 480 


Ala Cys Asn Thr Leu Asp Gly Thr Cys Thr Cys Ala Pro Gly Trp Arg 
                485                 490                 495     


Gly Glu Lys Cys Glu Leu Pro Cys Gln Asp Gly Thr Tyr Gly Leu Asn 
            500                 505                 510         


Cys Ala Glu Arg Cys Asp Cys Ser His Ala Asp Gly Cys His Pro Thr 
        515                 520                 525             


Thr Gly His Cys Arg Cys Leu Pro Gly Trp Ser Gly Leu Phe 
    530                 535                 540         


<210>  932
<211>  829
<212>  PRT
<213>  Homo Sapiens

<400>  932

Leu Asn Pro Glu Asp Pro Asn Val Cys Ser His Trp Glu Ser Tyr Ala 
1               5                   10                  15      


Val Thr Val Gln Glu Ser Tyr Ala His Pro Phe Asp Gln Ile Tyr Tyr 
            20                  25                  30          


Thr Arg Cys Thr Asp Ile Leu Asn Trp Phe Lys Cys Thr Arg His Arg 
        35                  40                  45              


Ile Ser Tyr Lys Thr Ala Tyr Arg Arg Gly Leu Arg Thr Met Tyr Arg 
    50                  55                  60                  


Arg Arg Ser Gln Cys Cys Pro Gly Tyr Tyr Glu Asn Gly Asp Phe Cys 
65                  70                  75                  80  


Ile Pro Leu Cys Thr Glu Glu Cys Val His Gly Arg Cys Val Ser Pro 
                85                  90                  95      


Asp Thr Cys His Cys Glu Pro Gly Trp Gly Gly Pro Asp Cys Ser Ser 
            100                 105                 110         


Gly Cys Asp Ser Asp His Trp Gly Pro His Cys Ser Asn Arg Cys Gln 
        115                 120                 125             


Cys Gln Asn Gly Ala Leu Cys Asn Pro Ile Thr Gly Ala Cys Val Cys 
    130                 135                 140                 


Ala Ala Gly Phe Arg Gly Trp Arg Cys Glu Glu Leu Cys Ala Pro Gly 
145                 150                 155                 160 


Thr His Gly Lys Gly Cys Gln Leu Pro Cys Gln Cys Arg His Gly Ala 
                165                 170                 175     


Ser Cys Asp Pro Arg Ala Gly Glu Cys Leu Cys Ala Pro Gly Tyr Thr 
            180                 185                 190         


Gly Val Tyr Cys Glu Glu Leu Cys Pro Pro Gly Ser His Gly Ala His 
        195                 200                 205             


Cys Glu Leu Arg Cys Pro Cys Gln Asn Gly Gly Thr Cys His His Ile 
    210                 215                 220                 


Thr Gly Glu Cys Ala Cys Pro Pro Gly Trp Thr Gly Ala Val Cys Ala 
225                 230                 235                 240 


Gln Pro Cys Pro Pro Gly Thr Phe Gly Gln Asn Cys Ser Gln Asp Cys 
                245                 250                 255     


Pro Cys His His Gly Gly Gln Cys Asp His Val Thr Gly Gln Cys His 
            260                 265                 270         


Cys Thr Ala Gly Tyr Met Gly Asp Arg Cys Gln Glu Glu Cys Pro Phe 
        275                 280                 285             


Gly Ser Phe Gly Phe Gln Cys Ser Gln Arg Cys Asp Cys His Asn Gly 
    290                 295                 300                 


Gly Gln Cys Ser Pro Thr Thr Gly Ala Cys Glu Cys Glu Pro Gly Tyr 
305                 310                 315                 320 


Lys Gly Pro Arg Cys Gln Glu Arg Leu Cys Pro Glu Gly Leu His Gly 
                325                 330                 335     


Pro Gly Cys Thr Leu Pro Cys Pro Cys Asp Ala Asp Asn Thr Ile Ser 
            340                 345                 350         


Cys His Pro Val Thr Gly Ala Cys Thr Cys Gln Pro Gly Trp Ser Gly 
        355                 360                 365             


His His Cys Asn Glu Ser Cys Pro Val Gly Tyr Tyr Gly Asp Gly Cys 
    370                 375                 380                 


Gln Leu Pro Cys Thr Cys Gln Asn Gly Ala Asp Cys His Ser Ile Thr 
385                 390                 395                 400 


Gly Gly Cys Thr Cys Ala Pro Gly Phe Met Gly Glu Val Cys Ala Val 
                405                 410                 415     


Ser Cys Ala Ala Gly Thr Tyr Gly Pro Asn Cys Ser Ser Ile Cys Ser 
            420                 425                 430         


Cys Asn Asn Gly Gly Thr Cys Ser Pro Val Asp Gly Ser Cys Thr Cys 
        435                 440                 445             


Lys Glu Gly Trp Gln Gly Leu Asp Cys Thr Leu Pro Cys Pro Ser Gly 
    450                 455                 460                 


Thr Trp Gly Leu Asn Cys Asn Glu Ser Cys Thr Cys Ala Asn Gly Ala 
465                 470                 475                 480 


Ala Cys Ser Pro Ile Asp Gly Ser Cys Ser Cys Thr Pro Gly Trp Leu 
                485                 490                 495     


Gly Asp Thr Cys Glu Leu Pro Cys Pro Asp Gly Thr Phe Gly Leu Asn 
            500                 505                 510         


Cys Ser Glu His Cys Asp Cys Ser His Ala Asp Gly Cys Asp Pro Val 
        515                 520                 525             


Thr Gly His Cys Cys Cys Leu Ala Gly Trp Thr Gly Ile Arg Cys Asp 
    530                 535                 540                 


Ser Thr Cys Pro Pro Gly Arg Trp Gly Pro Asn Cys Ser Val Ser Cys 
545                 550                 555                 560 


Ser Cys Glu Asn Gly Gly Ser Cys Ser Pro Glu Asp Gly Ser Cys Glu 
                565                 570                 575     


Cys Ala Pro Gly Phe Arg Gly Pro Leu Cys Gln Arg Ile Cys Pro Pro 
            580                 585                 590         


Gly Phe Tyr Gly His Gly Cys Ala Gln Pro Cys Pro Leu Cys Val His 
        595                 600                 605             


Ser Ser Arg Pro Cys His His Ile Ser Gly Ile Cys Glu Cys Leu Pro 
    610                 615                 620                 


Gly Phe Ser Gly Ala Leu Cys Asn Gln Val Cys Ala Gly Gly Tyr Phe 
625                 630                 635                 640 


Gly Gln Asp Cys Ala Gln Leu Cys Ser Cys Ala Asn Asn Gly Thr Cys 
                645                 650                 655     


Ser Pro Ile Asp Gly Ser Cys Gln Cys Phe Pro Gly Trp Ile Gly Lys 
            660                 665                 670         


Asp Cys Ser Gln Ala Cys Pro Pro Gly Phe Trp Gly Pro Ala Cys Phe 
        675                 680                 685             


His Ala Cys Ser Cys His Asn Gly Ala Ser Cys Ser Ala Glu Asp Gly 
    690                 695                 700                 


Ala Cys His Cys Thr Pro Gly Trp Thr Gly Leu Phe Cys Thr Gln Arg 
705                 710                 715                 720 


Cys Pro Ala Ala Phe Phe Gly Lys Asp Cys Gly Arg Val Cys Gln Cys 
                725                 730                 735     


Gln Asn Gly Ala Ser Cys Asp His Ile Ser Gly Lys Cys Thr Cys Arg 
            740                 745                 750         


Thr Gly Phe Thr Gly Gln His Cys Glu Gln Arg Cys Ala Pro Gly Thr 
        755                 760                 765             


Phe Gly Tyr Gly Cys Gln Gln Leu Cys Glu Cys Met Asn Asn Ser Thr 
    770                 775                 780                 


Cys Asp His Val Thr Gly Thr Cys Tyr Cys Ser Pro Gly Phe Lys Gly 
785                 790                 795                 800 


Ile Arg Cys Asp Gln Ala Ala Leu Met Met Glu Glu Leu Asn Pro Tyr 
                805                 810                 815     


Thr Lys Ile Ser Pro Ala Leu Gly Ala Glu Arg His Ser 
            820                 825                 


<210>  933
<211>  529
<212>  PRT
<213>  Homo Sapiens

<400>  933

Ala Val Ala Ser Ala Ala Ser Ala Gly Asn Val Thr Gly Gly Gly Gly 
1               5                   10                  15      


Ala Ala Gly Gln Val Asp Ala Ser Pro Gly Pro Gly Leu Arg Gly Glu 
            20                  25                  30          


Pro Ser His Pro Phe Pro Arg Ala Thr Ala Pro Thr Ala Gln Ala Pro 
        35                  40                  45              


Arg Thr Gly Pro Pro Arg Ala Thr Val His Arg Pro Leu Ala Ala Thr 
    50                  55                  60                  


Ser Pro Ala Gln Ser Pro Glu Thr Thr Pro Leu Trp Ala Thr Ala Gly 
65                  70                  75                  80  


Pro Ser Ser Thr Thr Phe Gln Ala Pro Leu Gly Pro Ser Pro Thr Thr 
                85                  90                  95      


Pro Pro Ala Ala Glu Arg Thr Ser Thr Thr Ser Gln Ala Pro Thr Arg 
            100                 105                 110         


Pro Ala Pro Thr Thr Leu Ser Thr Thr Thr Gly Pro Ala Pro Thr Thr 
        115                 120                 125             


Pro Val Ala Thr Thr Val Pro Ala Pro Thr Thr Pro Arg Thr Pro Thr 
    130                 135                 140                 


Pro Asp Leu Pro Ser Ser Ser Asn Ser Ser Val Leu Pro Thr Pro Pro 
145                 150                 155                 160 


Ala Thr Glu Ala Pro Ser Ser Pro Pro Pro Gly His Gln Trp Pro Val 
                165                 170                 175     


Ala Lys Met Pro Gln Lys Tyr Leu Gly Lys Tyr Ala Cys Glu Ser Asn 
            180                 185                 190         


Leu Lys Ser Lys Tyr Leu Pro Leu Thr Gln Pro Val Met Asn Leu Arg 
        195                 200                 205             


Val Ser Glu Ala Val Lys Thr Glu Tyr Val Cys Asn Cys Ser Val Val 
    210                 215                 220                 


Gly Ser Leu Asn Val Asn Arg Cys Asn Gln Thr Thr Gly Gln Cys Glu 
225                 230                 235                 240 


Cys Arg Pro Gly Tyr Gln Gly Leu His Cys Glu Thr Cys Lys Glu Gly 
                245                 250                 255     


Phe Tyr Leu Asn Tyr Thr Ser Gly Leu Cys Gln Pro Cys Asp Cys Ser 
            260                 265                 270         


Pro His Gly Ala Leu Ser Ile Pro Cys Asn Ser Ser Gly Lys Cys Gln 
        275                 280                 285             


Cys Lys Val Gly Val Ile Gly Ser Ile Cys Asp Arg Cys Gln Asp Gly 
    290                 295                 300                 


Tyr Tyr Gly Phe Ser Lys Asn Gly Cys Leu Pro Cys Gln Cys Asn Asn 
305                 310                 315                 320 


Arg Ser Ala Ser Cys Asp Ala Leu Thr Gly Ala Cys Leu Asn Cys Gln 
                325                 330                 335     


Glu Asn Ser Lys Gly Asn His Cys Glu Glu Cys Lys Glu Gly Phe Tyr 
            340                 345                 350         


Gln Ser Pro Asp Ala Thr Lys Glu Cys Leu Arg Cys Pro Cys Ser Ala 
        355                 360                 365             


Val Thr Ser Thr Gly Ser Cys Ser Ile Lys Ser Ser Glu Leu Glu Pro 
    370                 375                 380                 


Glu Cys Asp Gln Cys Lys Asp Gly Tyr Ile Gly Pro Asn Cys Asn Lys 
385                 390                 395                 400 


Cys Glu Asn Gly Tyr Tyr Asn Phe Asp Ser Ile Cys Arg Lys Cys Gln 
                405                 410                 415     


Cys His Gly His Val Asp Pro Val Lys Thr Pro Lys Ile Cys Lys Pro 
            420                 425                 430         


Glu Ser Gly Glu Cys Ile Asn Cys Leu His Asn Thr Thr Gly Phe Trp 
        435                 440                 445             


Cys Glu Asn Cys Leu Glu Gly Tyr Val His Asp Leu Glu Gly Asn Cys 
    450                 455                 460                 


Ile Lys Lys Glu Val Ile Leu Pro Thr Pro Glu Gly Ser Thr Ile Leu 
465                 470                 475                 480 


Val Ser Asn Ala Ser Leu Thr Thr Ser Val Pro Thr Pro Val Ile Asn 
                485                 490                 495     


Ser Thr Phe Thr Pro Thr Thr Leu Gln Thr Ile Phe Ser Val Ser Thr 
            500                 505                 510         


Ser Glu Asn Ser Thr Ser Ala Leu Ala Asp Val Ser Trp Thr Gln Phe 
        515                 520                 525             


Asn 
    


<210>  934
<211>  647
<212>  PRT
<213>  Homo Sapiens

<400>  934

Asn Gly Leu Arg Asp Pro Asn Thr Arg Trp Thr Phe Pro Ile Pro Tyr 
1               5                   10                  15      


Ile Leu Ala Asp Asn Leu Gly Leu Asn Ala Lys Gly Ala Ile Leu Tyr 
            20                  25                  30          


Ala Phe Glu Met Phe Arg Leu Lys Ser Cys Val Asp Phe Lys Pro Tyr 
        35                  40                  45              


Glu Gly Glu Ser Ser Tyr Ile Ile Phe Gln Gln Phe Asp Gly Cys Trp 
    50                  55                  60                  


Ser Glu Val Gly Asp Gln His Val Gly Gln Asn Ile Ser Ile Gly Gln 
65                  70                  75                  80  


Gly Cys Ala Tyr Lys Ala Ile Ile Glu His Glu Ile Leu His Ala Leu 
                85                  90                  95      


Gly Phe Tyr His Glu Gln Ser Arg Thr Asp Arg Asp Asp Tyr Val Asn 
            100                 105                 110         


Ile Trp Trp Asp Gln Ile Leu Ser Gly Tyr Gln His Asn Phe Asp Thr 
        115                 120                 125             


Tyr Asp Asp Ser Leu Ile Thr Asp Leu Asn Thr Pro Tyr Asp Tyr Glu 
    130                 135                 140                 


Ser Leu Met His Tyr Gln Pro Phe Ser Phe Asn Lys Asn Ala Ser Val 
145                 150                 155                 160 


Pro Thr Ile Thr Ala Lys Ile Pro Glu Phe Asn Ser Ile Ile Gly Gln 
                165                 170                 175     


Arg Leu Asp Phe Ser Ala Ile Asp Leu Glu Arg Leu Asn Arg Met Tyr 
            180                 185                 190         


Asn Cys Thr Thr Thr His Thr Leu Leu Asp His Cys Thr Phe Glu Lys 
        195                 200                 205             


Ala Asn Ile Cys Gly Met Ile Gln Gly Thr Arg Asp Asp Thr Asp Trp 
    210                 215                 220                 


Ala His Gln Asp Ser Ala Gln Ala Gly Glu Val Asp His Thr Leu Leu 
225                 230                 235                 240 


Gly Gln Cys Thr Gly Ala Gly Tyr Phe Met Gln Phe Ser Thr Ser Ser 
                245                 250                 255     


Gly Ser Ala Glu Glu Ala Ala Leu Leu Glu Ser Arg Ile Leu Tyr Pro 
            260                 265                 270         


Lys Arg Lys Gln Gln Cys Leu Gln Phe Phe Tyr Lys Met Thr Gly Ser 
        275                 280                 285             


Pro Ser Asp Arg Leu Val Val Trp Val Arg Arg Asp Asp Ser Thr Gly 
    290                 295                 300                 


Asn Val Arg Lys Leu Val Lys Val Gln Thr Phe Gln Gly Asp Asp Asp 
305                 310                 315                 320 


His Asn Trp Lys Ile Ala His Val Val Leu Lys Glu Glu Gln Lys Phe 
                325                 330                 335     


Arg Tyr Leu Phe Gln Gly Thr Lys Gly Asp Pro Gln Asn Ser Thr Gly 
            340                 345                 350         


Gly Ile Tyr Leu Asp Asp Ile Thr Leu Thr Glu Thr Pro Cys Pro Thr 
        355                 360                 365             


Gly Val Trp Thr Val Arg Asn Phe Ser Gln Val Leu Glu Asn Thr Ser 
    370                 375                 380                 


Lys Gly Asp Lys Leu Gln Ser Pro Arg Phe Tyr Asn Ser Glu Gly Tyr 
385                 390                 395                 400 


Gly Phe Gly Leu Thr Leu Tyr Pro Asn Ser Gly Glu Ser Ser Gly Tyr 
                405                 410                 415     


Leu Arg Leu Ala Phe His Val Cys Ser Gly Glu Asn Asp Ala Ile Leu 
            420                 425                 430         


Glu Trp Pro Val Glu Asn Arg Gln Val Ile Ile Thr Ile Leu Asp Gln 
        435                 440                 445             


Glu Pro Asp Val Arg Asn Arg Met Ser Ser Ser Met Val Phe Thr Thr 
    450                 455                 460                 


Ser Lys Ser His Thr Ser Pro Ala Ile Asn Asp Thr Val Ile Trp Asp 
465                 470                 475                 480 


Arg Pro Ser Arg Val Gly Thr Tyr His Thr Asp Cys Asn Cys Phe Arg 
                485                 490                 495     


Ser Ile Asp Leu Gly Trp Ser Gly Phe Ile Ser His Gln Met Leu Lys 
            500                 505                 510         


Arg Arg Ser Phe Leu Lys Asn Asp Asp Leu Ile Ile Phe Val Asp Phe 
        515                 520                 525             


Glu Asp Ile Thr His Leu Ser Gln Thr Glu Val Pro Thr Lys Gly Lys 
    530                 535                 540                 


Arg Leu Ser Pro Gln Gly Leu Ile Leu Gln Gly Gln Glu Gln Gln Val 
545                 550                 555                 560 


Ser Glu Glu Gly Ser Gly Lys Ala Met Leu Glu Glu Ala Leu Pro Val 
                565                 570                 575     


Ser Leu Ser Gln Gly Gln Pro Ser Arg Gln Lys Arg Ser Val Glu Asn 
            580                 585                 590         


Thr Gly Pro Leu Glu Asp His Asn Trp Pro Gln Tyr Phe Arg Asp Pro 
        595                 600                 605             


Cys Asp Pro Asn Pro Cys Gln Asn Asp Gly Ile Cys Val Asn Val Lys 
    610                 615                 620                 


Gly Met Ala Ser Cys Arg Cys Ile Ser Gly His Ala Phe Phe Tyr Thr 
625                 630                 635                 640 


Gly Glu Arg Cys Gln Ala Val 
                645         


<210>  935
<211>  591
<212>  PRT
<213>  Homo Sapiens

<400>  935

Asn Ser Ile Ile Gly Glu Lys Tyr Arg Trp Pro His Thr Ile Pro Tyr 
1               5                   10                  15      


Val Leu Glu Asp Ser Leu Glu Met Asn Ala Lys Gly Val Ile Leu Asn 
            20                  25                  30          


Ala Phe Glu Arg Tyr Arg Leu Lys Thr Cys Ile Asp Phe Lys Pro Trp 
        35                  40                  45              


Ala Gly Glu Thr Asn Tyr Ile Ser Val Phe Lys Gly Ser Gly Cys Trp 
    50                  55                  60                  


Ser Ser Val Gly Asn Arg Arg Val Gly Lys Gln Glu Leu Ser Ile Gly 
65                  70                  75                  80  


Ala Asn Cys Asp Arg Ile Ala Thr Val Gln His Glu Phe Leu His Ala 
                85                  90                  95      


Leu Gly Phe Trp His Glu Gln Ser Arg Ser Asp Arg Asp Asp Tyr Val 
            100                 105                 110         


Arg Ile Met Trp Asp Arg Ile Leu Ser Gly Arg Glu His Asn Phe Asn 
        115                 120                 125             


Thr Tyr Ser Asp Asp Ile Ser Asp Ser Leu Asn Val Pro Tyr Asp Tyr 
    130                 135                 140                 


Thr Ser Val Met His Tyr Ser Lys Thr Ala Phe Gln Asn Gly Thr Glu 
145                 150                 155                 160 


Pro Thr Ile Val Thr Arg Ile Ser Asp Phe Glu Asp Val Ile Gly Gln 
                165                 170                 175     


Arg Met Asp Phe Ser Asp Ser Asp Leu Leu Lys Leu Asn Gln Leu Tyr 
            180                 185                 190         


Asn Cys Ser Ser Ser Leu Ser Phe Met Asp Ser Cys Ser Phe Glu Leu 
        195                 200                 205             


Glu Asn Val Cys Gly Met Ile Gln Ser Ser Gly Asp Asn Ala Asp Trp 
    210                 215                 220                 


Gln Arg Val Ser Gln Val Pro Arg Gly Pro Glu Ser Asp His Ser Asn 
225                 230                 235                 240 


Met Gly Gln Cys Gln Gly Ser Gly Phe Phe Met His Phe Asp Ser Ser 
                245                 250                 255     


Ser Val Asn Val Gly Ala Thr Ala Val Leu Glu Ser Arg Thr Leu Tyr 
            260                 265                 270         


Pro Lys Arg Gly Phe Gln Cys Leu Gln Phe Tyr Leu Tyr Asn Ser Gly 
        275                 280                 285             


Ser Glu Ser Asp Gln Leu Asn Ile Tyr Ile Arg Glu Tyr Ser Ala Asp 
    290                 295                 300                 


Asn Val Asp Gly Asn Leu Thr Leu Val Glu Glu Ile Lys Glu Ile Pro 
305                 310                 315                 320 


Thr Gly Ser Trp Gln Leu Tyr His Val Thr Leu Lys Val Thr Lys Lys 
                325                 330                 335     


Phe Arg Val Val Phe Glu Gly Arg Lys Gly Ser Gly Ala Ser Leu Gly 
            340                 345                 350         


Gly Leu Ser Ile Asp Asp Ile Asn Leu Ser Glu Thr Arg Cys Pro His 
        355                 360                 365             


His Ile Trp His Ile Arg Asn Phe Thr Gln Phe Ile Gly Ser Pro Asn 
    370                 375                 380                 


Gly Thr Leu Tyr Ser Pro Pro Phe Tyr Ser Ser Lys Gly Tyr Ala Phe 
385                 390                 395                 400 


Gln Ile Tyr Leu Asn Leu Ala His Val Thr Asn Ala Gly Ile Tyr Phe 
                405                 410                 415     


His Leu Ile Ser Gly Ala Asn Asp Asp Gln Leu Gln Trp Pro Cys Pro 
            420                 425                 430         


Trp Gln Gln Ala Thr Met Thr Leu Leu Asp Gln Asn Pro Asp Ile Arg 
        435                 440                 445             


Gln Arg Met Ser Asn Gln Arg Ser Ile Thr Thr Asp Pro Phe Met Thr 
    450                 455                 460                 


Thr Asp Asn Gly Asn Tyr Phe Trp Asp Arg Pro Ser Lys Val Gly Thr 
465                 470                 475                 480 


Val Ala Leu Phe Pro Asn Gly Thr Gln Phe Arg Arg Gly Gly Gly Tyr 
                485                 490                 495     


Gly Thr Ser Ala Phe Ile Thr His Glu Arg Leu Lys Ser Arg Asp Phe 
            500                 505                 510         


Ile Lys Gly Asp Asp Val Tyr Ile Leu Leu Thr Val Glu Asp Ile Ser 
        515                 520                 525             


His Leu Asn Ser Thr Gln Ile Gln Leu Thr Pro Ala Pro Ser Val Gln 
    530                 535                 540                 


Asp Leu Cys Ser Lys Thr Thr Cys Lys Asn Asp Gly Val Cys Thr Val 
545                 550                 555                 560 


Arg Asp Gly Lys Ala Glu Cys Arg Cys Gln Ser Gly Glu Asp Trp Trp 
                565                 570                 575     


Tyr Met Gly Glu Arg Cys Glu Lys Arg Gly Ser Thr Arg Asp Thr 
            580                 585                 590     


<210>  936
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  936

Pro His Phe Thr Lys Gln Pro Glu Ser Met Asn Val Thr Arg Asn Thr 
1               5                   10                  15      


Ala Phe Asn Leu Thr Cys Gln Ala Val Gly Pro Pro Glu Pro Val Asn 
            20                  25                  30          


Ile Phe Trp Val Gln Asn Ser Ser Arg Val Asn Glu Gln Pro Glu Lys 
        35                  40                  45              


Ser Pro Ser Val Leu Thr Val Pro Gly Leu Thr Glu Met Ala Val Phe 
    50                  55                  60                  


Ser Cys Glu Ala His Asn Asp Lys Gly Leu Thr Val Ser Lys Gly Val 
65                  70                  75                  80  


Gln Ile Asn Ile Lys Ala Ile Pro Ser Pro Pro Thr Glu Val Ser Ile 
                85                  90                  95      


Arg Asn Ser Thr Ala His Ser Ile Leu Ile Ser Trp Val Pro Gly Phe 
            100                 105                 110         


Asp Gly Tyr Ser Pro Phe Arg Asn Cys Ser Ile Gln Val Lys Glu Ala 
        115                 120                 125             


Asp Pro Leu Ser Asn Gly Ser Val Met Ile Phe Asn Thr Ser Ala Leu 
    130                 135                 140                 


Pro His Leu Tyr Gln Ile Lys Gln Leu Gln Ala Leu Ala Asn Tyr Ser 
145                 150                 155                 160 


Ile Gly Val Ser Cys Met Asn Glu Ile Gly Trp Ser Ala Val Ser Pro 
                165                 170                 175     


Trp Ile Leu Ala Ser Thr Thr Glu Gly Ala Pro Ser Val Ala Pro Leu 
            180                 185                 190         


Asn Val Thr Val Phe Leu Asn Glu Ser Ser Asp Asn Val Asp Ile Arg 
        195                 200                 205             


Trp Met Lys Pro Pro Thr Lys Gln Gln Asp Gly Glu Leu Val Gly Tyr 
    210                 215                 220                 


Arg Ile Ser His Val Trp Gln Ser Ala Gly Ile Ser Lys Glu Leu Leu 
225                 230                 235                 240 


Glu Glu Val Gly Gln Asn Gly Ser Arg Ala Arg Ile Ser Val Gln Val 
                245                 250                 255     


His Asn Ala Thr Cys Thr Val Arg Ile Ala Ala Val Thr Lys Gly Gly 
            260                 265                 270         


Val Gly Pro Phe Ser Asp Pro Val Lys Ile Phe Ile Pro Ala His Gly 
        275                 280                 285             


Trp Val Asp Tyr Ala Pro Ser Ser Thr Pro Ala Pro Gly Asn Ala Asp 
    290                 295                 300                 


Pro Val Leu Ile Ile 
305                 


<210>  937
<211>  908
<212>  PRT
<213>  Homo Sapiens

<400>  937

Glu Cys Lys Glu Ala Leu Ala Lys Ser Glu Met Asn Val Asn Met Lys 
1               5                   10                  15      


Tyr Gln Leu Pro Asn Phe Thr Ala Glu Thr Pro Ile Gln Asn Val Ile 
            20                  25                  30          


Leu His Glu His His Ile Phe Leu Gly Ala Thr Asn Tyr Ile Tyr Val 
        35                  40                  45              


Leu Asn Glu Glu Asp Leu Gln Lys Val Ala Glu Tyr Lys Thr Gly Pro 
    50                  55                  60                  


Val Leu Glu His Pro Asp Cys Phe Pro Cys Gln Asp Cys Ser Ser Lys 
65                  70                  75                  80  


Ala Asn Leu Ser Gly Gly Val Trp Lys Asp Asn Ile Asn Met Ala Leu 
                85                  90                  95      


Val Val Asp Thr Tyr Tyr Asp Asp Gln Leu Ile Ser Cys Gly Ser Val 
            100                 105                 110         


Asn Arg Gly Thr Cys Gln Arg His Val Phe Pro His Asn His Thr Ala 
        115                 120                 125             


Asp Ile Gln Ser Glu Val His Cys Ile Phe Ser Pro Gln Ile Glu Glu 
    130                 135                 140                 


Pro Ser Gln Cys Pro Asp Cys Val Val Ser Ala Leu Gly Ala Lys Val 
145                 150                 155                 160 


Leu Ser Ser Val Lys Asp Arg Phe Ile Asn Phe Phe Val Gly Asn Thr 
                165                 170                 175     


Ile Asn Ser Ser Tyr Phe Pro Asp His Pro Leu His Ser Ile Ser Val 
            180                 185                 190         


Arg Arg Leu Lys Glu Thr Lys Asp Gly Phe Met Phe Leu Thr Asp Gln 
        195                 200                 205             


Ser Tyr Ile Asp Val Leu Pro Glu Phe Arg Asp Ser Tyr Pro Ile Lys 
    210                 215                 220                 


Tyr Val His Ala Phe Glu Ser Asn Asn Phe Ile Tyr Phe Leu Thr Val 
225                 230                 235                 240 


Gln Arg Glu Thr Leu Asp Ala Gln Thr Phe His Thr Arg Ile Ile Arg 
                245                 250                 255     


Phe Cys Ser Ile Asn Ser Gly Leu His Ser Tyr Met Glu Met Pro Leu 
            260                 265                 270         


Glu Cys Ile Leu Thr Glu Lys Arg Lys Lys Arg Ser Thr Lys Lys Glu 
        275                 280                 285             


Val Phe Asn Ile Leu Gln Ala Ala Tyr Val Ser Lys Pro Gly Ala Gln 
    290                 295                 300                 


Leu Ala Arg Gln Ile Gly Ala Ser Leu Asn Asp Asp Ile Leu Phe Gly 
305                 310                 315                 320 


Val Phe Ala Gln Ser Lys Pro Asp Ser Ala Glu Pro Met Asp Arg Ser 
                325                 330                 335     


Ala Met Cys Ala Phe Pro Ile Lys Tyr Val Asn Asp Phe Phe Asn Lys 
            340                 345                 350         


Ile Val Asn Lys Asn Asn Val Arg Cys Leu Gln His Phe Tyr Gly Pro 
        355                 360                 365             


Asn His Glu His Cys Phe Asn Arg Thr Leu Leu Arg Asn Ser Ser Gly 
    370                 375                 380                 


Cys Glu Ala Arg Arg Asp Glu Tyr Arg Thr Glu Phe Thr Thr Ala Leu 
385                 390                 395                 400 


Gln Arg Val Asp Leu Phe Met Gly Gln Phe Ser Glu Val Leu Leu Thr 
                405                 410                 415     


Ser Ile Ser Thr Phe Ile Lys Gly Asp Leu Thr Ile Ala Asn Leu Gly 
            420                 425                 430         


Thr Ser Glu Gly Arg Phe Met Gln Val Val Val Ser Arg Ser Gly Pro 
        435                 440                 445             


Ser Thr Pro His Val Asn Phe Leu Leu Asp Ser His Pro Val Ser Pro 
    450                 455                 460                 


Glu Val Ile Val Glu His Thr Leu Asn Gln Asn Gly Tyr Thr Leu Val 
465                 470                 475                 480 


Ile Thr Gly Lys Lys Ile Thr Lys Ile Pro Leu Asn Gly Leu Gly Cys 
                485                 490                 495     


Arg His Phe Gln Ser Cys Ser Gln Cys Leu Ser Ala Pro Pro Phe Val 
            500                 505                 510         


Gln Cys Gly Trp Cys His Asp Lys Cys Val Arg Ser Glu Glu Cys Leu 
        515                 520                 525             


Ser Gly Thr Trp Thr Gln Gln Ile Cys Leu Pro Ala Ile Tyr Lys Val 
    530                 535                 540                 


Phe Pro Asn Ser Ala Pro Leu Glu Gly Gly Thr Arg Leu Thr Ile Cys 
545                 550                 555                 560 


Gly Trp Asp Phe Gly Phe Arg Arg Asn Asn Lys Phe Asp Leu Lys Lys 
                565                 570                 575     


Thr Arg Val Leu Leu Gly Asn Glu Ser Cys Thr Leu Thr Leu Ser Glu 
            580                 585                 590         


Ser Thr Met Asn Thr Leu Lys Cys Thr Val Gly Pro Ala Met Asn Lys 
        595                 600                 605             


His Phe Asn Met Ser Ile Ile Ile Ser Asn Gly His Gly Thr Thr Gln 
    610                 615                 620                 


Tyr Ser Thr Phe Ser Tyr Val Asp Pro Val Ile Thr Ser Ile Ser Pro 
625                 630                 635                 640 


Lys Tyr Gly Pro Met Ala Gly Gly Thr Leu Leu Thr Leu Thr Gly Asn 
                645                 650                 655     


Tyr Leu Asn Ser Gly Asn Ser Arg His Ile Ser Ile Gly Gly Lys Thr 
            660                 665                 670         


Cys Thr Leu Lys Ser Val Ser Asn Ser Ile Leu Glu Cys Tyr Thr Pro 
        675                 680                 685             


Ala Gln Thr Ile Ser Thr Glu Phe Ala Val Lys Leu Lys Ile Asp Leu 
    690                 695                 700                 


Ala Asn Arg Glu Thr Ser Ile Phe Ser Tyr Arg Glu Asp Pro Ile Val 
705                 710                 715                 720 


Tyr Glu Ile His Pro Thr Lys Ser Phe Ile Ser Gly Gly Ser Thr Ile 
                725                 730                 735     


Thr Gly Val Gly Lys Asn Leu Asn Ser Val Ser Val Pro Arg Met Val 
            740                 745                 750         


Ile Asn Val His Glu Ala Gly Arg Asn Phe Thr Val Ala Cys Gln His 
        755                 760                 765             


Arg Ser Asn Ser Glu Ile Ile Cys Cys Thr Thr Pro Ser Leu Gln Gln 
    770                 775                 780                 


Leu Asn Leu Gln Leu Pro Leu Lys Thr Lys Ala Phe Phe Met Leu Asp 
785                 790                 795                 800 


Gly Ile Leu Ser Lys Tyr Phe Asp Leu Ile Tyr Val His Asn Pro Val 
                805                 810                 815     


Phe Lys Pro Phe Glu Lys Pro Val Met Ile Ser Met Gly Asn Glu Asn 
            820                 825                 830         


Val Leu Glu Ile Lys Gly Asn Asp Ile Asp Pro Glu Ala Val Lys Gly 
        835                 840                 845             


Glu Val Leu Lys Val Gly Asn Lys Ser Cys Glu Asn Ile His Leu His 
    850                 855                 860                 


Ser Glu Ala Val Leu Cys Thr Val Pro Asn Asp Leu Leu Lys Leu Asn 
865                 870                 875                 880 


Ser Glu Leu Asn Ile Glu Trp Lys Gln Ala Ile Ser Ser Thr Val Leu 
                885                 890                 895     


Gly Lys Val Ile Val Gln Pro Asp Gln Asn Phe Thr 
            900                 905             


<210>  938
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  938

Ala Phe Val Leu Glu Asp Val Asp Phe Asp Gln Met Val Ser Leu Glu 
1               5                   10                  15      


Ala Asn Arg Ser Ser Tyr Asn Ala Ser Phe Pro Ser Ser Phe Glu Leu 
            20                  25                  30          


Ser Ala Ser Ser His Ser Asp Asp Asp Val Ile Ile Ala Lys Glu Gly 
        35                  40                  45              


Thr Ser Val Ser Ile Glu Cys Leu Leu Thr Ala Ser His Tyr Glu Asp 
    50                  55                  60                  


Val His Trp His Asn Ser Lys Gly Gln Gln Leu Asp Gly Arg Ser Arg 
65                  70                  75                  80  


Gly Gly Lys Trp Leu Val Ser Asp Asn Phe Leu Asn Ile Thr Asn Val 
                85                  90                  95      


Ala Phe Asp Asp Arg Gly Leu Tyr Thr Cys Phe Val Thr Ser Pro Ile 
            100                 105                 110         


Arg Ala Ser Tyr Ser Val Thr Leu Arg Val Ile Phe Thr Ser Gly Asp 
        115                 120                 125             


Met 
    


<210>  939
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  939

Lys Ser Val Thr Asn Ser Thr Leu Asn Gly Thr Asn Val Val Leu Gly 
1               5                   10                  15      


Ser Val Pro Val Ile Ile Ala Arg Thr Asp His Ile Ile Val Lys Glu 
            20                  25                  30          


Gly Asn Ser Ala Leu Ile Asn Cys Ser Val Tyr Gly Ile Pro Asp Pro 
        35                  40                  45              


Gln Phe Lys Trp Tyr Asn Ser Ile Gly Lys Leu Leu Lys Glu Glu Glu 
    50                  55                  60                  


Asp Glu Lys Glu Arg Gly Gly Gly Lys Trp Gln Met His Asp Ser Gly 
65                  70                  75                  80  


Leu Leu Asn Ile Thr Lys Val Ser Phe Ser Asp Arg Gly Lys Tyr Thr 
                85                  90                  95      


Cys Val Ala Ser Asn Ile Tyr Gly Thr Val Asn Asn Thr Val Thr Leu 
            100                 105                 110         


Arg Val Ile Phe Thr Ser Gly Asp Met 
        115                 120     


<210>  940
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  940

Leu Asp Ile Cys Ser Lys Asn Pro Cys His Asn Gly Gly Leu Cys Glu 
1               5                   10                  15      


Glu Ile Ser Gln Glu Val Arg Gly Asp Val Phe Pro Ser Tyr Thr Cys 
            20                  25                  30          


Thr Cys Leu Lys Gly Tyr Ala Gly Asn His Cys Glu Thr Lys Cys Val 
        35                  40                  45              


Glu Pro Leu Gly Met Glu Asn Gly Asn Ile Ala Asn Ser Gln Ile Ala 
    50                  55                  60                  


Ala Ser Ser Val Arg Val Thr Phe Leu Gly Leu Gln His Trp Val Pro 
65                  70                  75                  80  


Glu Leu Ala Arg Leu Asn Arg Ala Gly Met Val Asn Ala Trp Thr Pro 
                85                  90                  95      


Ser Ser Asn Asp Asp Asn Pro Trp Ile Gln Val Asn Leu Leu Arg Arg 
            100                 105                 110         


Met Trp Val Thr Gly Val Val Thr Gln Gly Ala Ser Arg Leu Ala Ser 
        115                 120                 125             


His Glu Tyr Leu Lys Ala Phe Lys Val Ala Tyr Ser Leu Asn Gly His 
    130                 135                 140                 


Glu Phe Asp Phe Ile His Asp Val Asn Lys Lys His Lys Glu Phe Val 
145                 150                 155                 160 


Gly Asn Trp Asn Lys Asn Ala Val His Val Asn Leu Phe Glu Thr Pro 
                165                 170                 175     


Val Glu Ala Gln Tyr Val Arg Leu Tyr Pro Thr Ser Cys His Thr Ala 
            180                 185                 190         


Cys Thr Leu Arg Phe Glu Leu Leu Gly Cys Glu Leu Asn Gly Cys Ala 
        195                 200                 205             


Asn Pro Leu Gly Leu Lys Asn Asn Ser Ile Pro Asp Lys Gln Ile Thr 
    210                 215                 220                 


Ala Ser Ser Ser Tyr Lys Thr Trp Gly Leu His Leu Phe Ser Trp Asn 
225                 230                 235                 240 


Pro Ser Tyr Ala Arg Leu Asp Lys Gln Gly Asn Phe Asn Ala Trp Val 
                245                 250                 255     


Ala Gly Ser Tyr Gly Asn Asp Gln Trp Leu Gln Ile Phe Pro Gly Asn 
            260                 265                 270         


Trp Asp Asn His Ser His Lys Lys Asn Leu Phe Glu Thr Pro Ile Leu 
        275                 280                 285             


Ala Arg Tyr Val Arg Ile Leu Pro Val Ala Trp His Asn Arg Ile Ala 
    290                 295                 300                 


Leu Arg Leu Glu Leu Leu Gly Cys 
305                 310         


<210>  941
<211>  690
<212>  PRT
<213>  Homo Sapiens

<400>  941

Gly Met Glu Val Arg Trp Cys Ala Thr Ser Asp Pro Glu Gln His Lys 
1               5                   10                  15      


Cys Gly Asn Met Ser Glu Ala Phe Arg Glu Ala Gly Ile Gln Pro Ser 
            20                  25                  30          


Leu Leu Cys Val Arg Gly Thr Ser Ala Asp His Cys Val Gln Leu Ile 
        35                  40                  45              


Ala Ala Gln Glu Ala Asp Ala Ile Thr Leu Asp Gly Gly Ala Ile Tyr 
    50                  55                  60                  


Glu Ala Gly Lys Glu His Gly Leu Lys Pro Val Val Gly Glu Val Tyr 
65                  70                  75                  80  


Asp Gln Glu Val Gly Thr Ser Tyr Tyr Ala Val Ala Val Val Arg Arg 
                85                  90                  95      


Ser Ser His Val Thr Ile Asp Thr Leu Lys Gly Val Lys Ser Cys His 
            100                 105                 110         


Thr Gly Ile Asn Arg Thr Val Gly Trp Asn Val Pro Val Gly Tyr Leu 
        115                 120                 125             


Val Glu Ser Gly Arg Leu Ser Val Met Gly Cys Asp Val Leu Lys Ala 
    130                 135                 140                 


Val Ser Asp Tyr Phe Gly Gly Ser Cys Val Pro Gly Ala Gly Glu Thr 
145                 150                 155                 160 


Ser Tyr Ser Glu Ser Leu Cys Arg Leu Cys Arg Gly Asp Ser Ser Gly 
                165                 170                 175     


Glu Gly Val Cys Asp Lys Ser Pro Leu Glu Arg Tyr Tyr Asp Tyr Ser 
            180                 185                 190         


Gly Ala Phe Arg Cys Leu Ala Glu Gly Ala Gly Asp Val Ala Phe Val 
        195                 200                 205             


Lys His Ser Thr Val Leu Glu Asn Thr Asp Gly Lys Thr Leu Pro Ser 
    210                 215                 220                 


Trp Gly Gln Ala Leu Leu Ser Gln Asp Phe Glu Leu Leu Cys Arg Asp 
225                 230                 235                 240 


Gly Ser Arg Ala Asp Val Thr Glu Trp Arg Gln Cys His Leu Ala Arg 
                245                 250                 255     


Val Pro Ala His Ala Val Val Val Arg Ala Asp Thr Asp Gly Gly Leu 
            260                 265                 270         


Ile Phe Arg Leu Leu Asn Glu Gly Gln Arg Leu Phe Ser His Glu Gly 
        275                 280                 285             


Ser Ser Phe Gln Met Phe Ser Ser Glu Ala Tyr Gly Gln Lys Asp Leu 
    290                 295                 300                 


Leu Phe Lys Asp Ser Thr Ser Glu Leu Val Pro Ile Ala Thr Gln Thr 
305                 310                 315                 320 


Tyr Glu Ala Trp Leu Gly His Glu Tyr Leu His Ala Met Lys Gly Leu 
                325                 330                 335     


Leu Cys Asp Pro Asn Arg Leu Pro Pro Tyr Leu Arg Trp Cys Val Leu 
            340                 345                 350         


Ser Thr Pro Glu Ile Gln Lys Cys Gly Asp Met Ala Val Ala Phe Arg 
        355                 360                 365             


Arg Gln Arg Leu Lys Pro Glu Ile Gln Cys Val Ser Ala Lys Ser Pro 
    370                 375                 380                 


Gln His Cys Met Glu Arg Ile Gln Ala Glu Gln Val Asp Ala Val Thr 
385                 390                 395                 400 


Leu Ser Gly Glu Asp Ile Tyr Thr Ala Gly Lys Thr Tyr Gly Leu Val 
                405                 410                 415     


Pro Ala Ala Gly Glu His Tyr Ala Pro Glu Asp Ser Ser Asn Ser Tyr 
            420                 425                 430         


Tyr Val Val Ala Val Val Arg Arg Asp Ser Ser His Ala Phe Thr Leu 
        435                 440                 445             


Asp Glu Leu Arg Gly Lys Arg Ser Cys His Ala Gly Phe Gly Ser Pro 
    450                 455                 460                 


Ala Gly Trp Asp Val Pro Val Gly Ala Leu Ile Gln Arg Gly Phe Ile 
465                 470                 475                 480 


Arg Pro Lys Asp Cys Asp Val Leu Thr Ala Val Ser Glu Phe Phe Asn 
                485                 490                 495     


Ala Ser Cys Val Pro Val Asn Asn Pro Lys Asn Tyr Pro Ser Ser Leu 
            500                 505                 510         


Cys Ala Leu Cys Val Gly Asp Glu Gln Gly Arg Asn Lys Cys Val Gly 
        515                 520                 525             


Asn Ser Gln Glu Arg Tyr Tyr Gly Tyr Arg Gly Ala Phe Arg Cys Leu 
    530                 535                 540                 


Val Glu Asn Ala Gly Asp Val Ala Phe Val Arg His Thr Thr Val Phe 
545                 550                 555                 560 


Asp Asn Thr Asn Gly His Asn Ser Glu Pro Trp Ala Ala Glu Leu Arg 
                565                 570                 575     


Ser Glu Asp Tyr Glu Leu Leu Cys Pro Asn Gly Ala Arg Ala Glu Val 
            580                 585                 590         


Ser Gln Phe Ala Ala Cys Asn Leu Ala Gln Ile Pro Pro His Ala Val 
        595                 600                 605             


Met Val Arg Pro Asp Thr Asn Ile Phe Thr Val Tyr Gly Leu Leu Asp 
    610                 615                 620                 


Lys Ala Gln Asp Leu Phe Gly Asp Asp His Asn Lys Asn Gly Phe Lys 
625                 630                 635                 640 


Met Phe Asp Ser Ser Asn Tyr His Gly Gln Asp Leu Leu Phe Lys Asp 
                645                 650                 655     


Ala Thr Val Arg Ala Val Pro Val Gly Glu Lys Thr Thr Tyr Arg Gly 
            660                 665                 670         


Trp Leu Gly Leu Asp Tyr Val Ala Ala Leu Glu Gly Met Ser Ser Gln 
        675                 680                 685             


Gln Cys 
    690 


<210>  942
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  942

Glu Pro His Ser Leu Arg Tyr Asn Leu Thr Val Leu Ser Trp Asp Gly 
1               5                   10                  15      


Ser Val Gln Ser Gly Phe Leu Thr Glu Val His Leu Asp Gly Gln Pro 
            20                  25                  30          


Phe Leu Arg Cys Asp Arg Gln Lys Cys Arg Ala Lys Pro Gln Gly Gln 
        35                  40                  45              


Trp Ala Glu Asp Val Leu Gly Asn Lys Thr Trp Asp Arg Glu Thr Arg 
    50                  55                  60                  


Asp Leu Thr Gly Asn Gly Lys Asp Leu Arg Met Thr Leu Ala His Ile 
65                  70                  75                  80  


Lys Asp Gln Lys Glu Gly Leu His Ser Leu Gln Glu Ile Arg Val Cys 
                85                  90                  95      


Glu Ile His Glu Asp Asn Ser Thr Arg Ser Ser Gln His Phe Tyr Tyr 
            100                 105                 110         


Asp Gly Glu Leu Phe Leu Ser Gln Asn Leu Glu Thr Glu Glu Trp Thr 
        115                 120                 125             


Met Pro Gln Ser Ser Arg Ala Gln Thr Leu Ala Met Asn Val Arg Asn 
    130                 135                 140                 


Phe Leu Lys Glu Asp Ala Met Lys Thr Lys Thr His Tyr His Ala Met 
145                 150                 155                 160 


His Ala Asp Cys Leu Gln Glu Leu Arg Arg Tyr Leu Lys Ser Gly Val 
                165                 170                 175     


Val Leu Arg Arg Thr Val Pro Pro Met Val Asn Val Thr Arg Ser Glu 
            180                 185                 190         


Ala Ser Glu Gly Asn Ile Thr Val Thr Cys Arg Ala Ser Gly Phe Tyr 
        195                 200                 205             


Pro Trp Asn Ile Thr Leu Ser Trp Arg Gln Asp Gly Val Ser Leu Ser 
    210                 215                 220                 


His Asp Thr Gln Gln Trp Gly Asp Val Leu Pro Asp Gly Asn Gly Thr 
225                 230                 235                 240 


Tyr Gln Thr Trp Val Ala Thr Arg Ile Cys Gln Gly Glu Glu Gln Arg 
                245                 250                 255     


Phe Thr Cys Tyr Met Glu His Ser Gly Asn His Ser Thr His Pro Val 
            260                 265                 270         


Pro Ser Gly Lys Val Leu Val Leu Gln Ser His Trp 
        275                 280                 


<210>  943
<211>  244
<212>  PRT
<213>  Homo Sapiens

<400>  943

Ala Glu Pro His Ser Leu Arg Tyr Asn Leu Met Val Leu Ser Gln Asp 
1               5                   10                  15      


Gly Ser Val Gln Ser Gly Phe Leu Ala Glu Gly His Leu Asp Gly Gln 
            20                  25                  30          


Pro Phe Leu Arg Tyr Asp Arg Gln Lys Arg Arg Ala Lys Pro Gln Gly 
        35                  40                  45              


Gln Trp Ala Glu Asp Val Leu Gly Ala Glu Thr Trp Asp Thr Glu Thr 
    50                  55                  60                  


Glu Asp Leu Thr Glu Asn Gly Gln Asp Leu Arg Arg Thr Leu Thr His 
65                  70                  75                  80  


Ile Lys Asp Gln Lys Gly Val Pro Gln Ser Ser Arg Ala Gln Thr Leu 
                85                  90                  95      


Ala Met Asn Val Thr Asn Phe Trp Lys Glu Asp Ala Met Lys Thr Lys 
            100                 105                 110         


Thr His Tyr Arg Ala Met Gln Ala Asp Cys Leu Gln Lys Leu Gln Arg 
        115                 120                 125             


Tyr Leu Lys Ser Gly Val Ala Ile Arg Arg Thr Val Pro Pro Met Val 
    130                 135                 140                 


Asn Val Thr Cys Ser Glu Val Ser Glu Gly Asn Ile Thr Val Thr Cys 
145                 150                 155                 160 


Arg Ala Ser Ser Phe Tyr Pro Arg Asn Ile Thr Leu Thr Trp Arg Gln 
                165                 170                 175     


Asp Gly Val Ser Leu Ser His Asn Thr Gln Gln Trp Gly Asp Val Leu 
            180                 185                 190         


Pro Asp Gly Asn Gly Thr Tyr Gln Thr Trp Val Ala Thr Arg Ile Arg 
        195                 200                 205             


Gln Gly Glu Glu Gln Arg Phe Thr Cys Tyr Met Glu His Ser Gly Asn 
    210                 215                 220                 


His Gly Thr His Pro Val Pro Ser Gly Lys Ala Leu Val Leu Gln Ser 
225                 230                 235                 240 


Gln Arg Thr Asp 
                


<210>  944
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  944

Pro Met Phe Ile Val Asn Thr Asn Val Pro Arg Ala Ser Val Pro Asp 
1               5                   10                  15      


Gly Phe Leu Ser Glu Leu Thr Gln Gln Leu Ala Gln Ala Thr Gly Lys 
            20                  25                  30          


Pro Pro Gln Tyr Ile Ala Val His Val Val Pro Asp Gln Leu Met Ala 
        35                  40                  45              


Phe Gly Gly Ser Ser Glu Pro Cys Ala Leu Cys Ser Leu His Ser Ile 
    50                  55                  60                  


Gly Lys Ile Gly Gly Ala Gln Asn Arg Ser Tyr Ser Lys Leu Leu Cys 
65                  70                  75                  80  


Gly Leu Leu Ala Glu Arg Leu Arg Ile Ser Pro Asp Arg Val Tyr Ile 
                85                  90                  95      


Asn Tyr Tyr Asp Met Asn Ala Ala Asn Val Gly Trp Asn Asn Ser Thr 
            100                 105                 110         


Phe Ala 
        


<210>  945
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  945

Arg Lys Ala Val Leu Asp Cys Glu Ala Met Lys Thr Asn Glu Phe Pro 
1               5                   10                  15      


Ser Pro Cys Leu Asp Ser Lys Thr Lys Val Val Met Lys Gly Gln Asn 
            20                  25                  30          


Val Ser Met Phe Cys Ser His Lys Asn Lys Ser Leu Gln Ile Thr Tyr 
        35                  40                  45              


Ser Leu Phe Arg Arg Lys Thr His Leu Gly Thr Gln Asp Gly Lys Gly 
    50                  55                  60                  


Glu Pro Ala Ile Phe Asn Leu Ser Ile Thr Glu Ala His Glu Ser Gly 
65                  70                  75                  80  


Pro Tyr Lys Cys Lys Ala Gln Val Thr Ser Cys Ser Lys Tyr Ser Arg 
                85                  90                  95      


Asp Phe Ser Phe Thr Ile Val Asp Pro Val Thr Ser Pro Val Leu Asn 
            100                 105                 110         


Ile Met Val Ile Gln Thr Glu Thr Asp Arg His Ile Thr Leu His Cys 
        115                 120                 125             


Leu Ser Val Asn Gly Ser Leu Pro Ile Asn Tyr Thr Phe Phe Glu Asn 
    130                 135                 140                 


His Val Ala Ile Ser Pro Ala Ile Ser Lys Tyr Asp Arg Glu Pro Ala 
145                 150                 155                 160 


Glu Phe Asn Leu Thr Lys Lys Asn Pro Gly Glu Glu Glu Glu Tyr Arg 
                165                 170                 175     


Cys Glu Ala Lys Asn Arg Leu Pro Asn Tyr Ala Thr Tyr Ser His Pro 
            180                 185                 190         


Val Thr Met Pro Ser Thr Gly Gly Asp Ser Cys Pro Phe Cys Leu Lys 
        195                 200                 205             


<210>  946
<211>  494
<212>  PRT
<213>  Homo Sapiens

<400>  946

Tyr Ala Leu Thr Gly Arg Lys Trp Asn Asn His His Leu Thr Phe Ser 
1               5                   10                  15      


Ile Gln Asn Tyr Thr Glu Lys Leu Gly Trp Tyr His Ser Met Glu Ala 
            20                  25                  30          


Val Arg Arg Ala Phe Arg Val Trp Glu Gln Ala Thr Pro Leu Val Phe 
        35                  40                  45              


Gln Glu Val Pro Tyr Glu Asp Ile Arg Leu Arg Arg Gln Lys Glu Ala 
    50                  55                  60                  


Asp Ile Met Val Leu Phe Ala Ser Gly Phe His Gly Asp Ser Ser Pro 
65                  70                  75                  80  


Phe Asp Gly Thr Gly Gly Phe Leu Ala His Ala Tyr Phe Pro Gly Pro 
                85                  90                  95      


Gly Leu Gly Gly Asp Thr His Phe Asp Ala Asp Glu Pro Trp Thr Phe 
            100                 105                 110         


Ser Ser Thr Asp Leu His Gly Asn Asn Leu Phe Leu Val Ala Val His 
        115                 120                 125             


Glu Leu Gly His Ala Leu Gly Leu Glu His Ser Ser Asn Pro Asn Ala 
    130                 135                 140                 


Ile Met Ala Pro Phe Tyr Gln Trp Lys Asp Val Asp Asn Phe Lys Leu 
145                 150                 155                 160 


Pro Glu Asp Asp Leu Arg Gly Ile Gln Gln Leu Tyr Gly Thr Pro Asp 
                165                 170                 175     


Gly Gln Pro Gln Pro Thr Gln Pro Leu Pro Thr Val Thr Pro Arg Arg 
            180                 185                 190         


Pro Gly Arg Pro Asp His Arg Pro Pro Arg Pro Pro Gln Pro Pro Pro 
        195                 200                 205             


Pro Gly Gly Lys Pro Glu Arg Pro Pro Lys Pro Gly Pro Pro Val Gln 
    210                 215                 220                 


Pro Arg Ala Thr Glu Arg Pro Asp Gln Tyr Gly Pro Asn Ile Cys Asp 
225                 230                 235                 240 


Gly Asp Phe Asp Thr Val Ala Met Leu Arg Gly Glu Met Phe Val Phe 
                245                 250                 255     


Lys Gly Arg Trp Phe Trp Arg Val Arg His Asn Arg Val Leu Asp Asn 
            260                 265                 270         


Tyr Pro Met Pro Ile Gly His Phe Trp Arg Gly Leu Pro Gly Asp Ile 
        275                 280                 285             


Ser Ala Ala Tyr Glu Arg Gln Asp Gly Arg Phe Val Phe Phe Lys Gly 
    290                 295                 300                 


Asp Arg Tyr Trp Leu Phe Arg Glu Ala Asn Leu Glu Pro Gly Tyr Pro 
305                 310                 315                 320 


Gln Pro Leu Thr Ser Tyr Gly Leu Gly Ile Pro Tyr Asp Arg Ile Asp 
                325                 330                 335     


Thr Ala Ile Trp Trp Glu Pro Thr Gly His Thr Phe Phe Phe Gln Glu 
            340                 345                 350         


Asp Arg Tyr Trp Arg Phe Asn Glu Glu Thr Gln Arg Gly Asp Pro Gly 
        355                 360                 365             


Tyr Pro Lys Pro Ile Ser Val Trp Gln Gly Ile Pro Ala Ser Pro Lys 
    370                 375                 380                 


Gly Ala Phe Leu Ser Asn Asp Ala Ala Tyr Thr Tyr Phe Tyr Lys Gly 
385                 390                 395                 400 


Thr Lys Tyr Trp Lys Phe Asp Asn Glu Arg Leu Arg Met Glu Pro Gly 
                405                 410                 415     


Tyr Pro Lys Ser Ile Leu Arg Asp Phe Met Gly Cys Gln Glu His Val 
            420                 425                 430         


Glu Pro Gly Pro Arg Trp Pro Asp Val Ala Arg Pro Pro Phe Asn Pro 
        435                 440                 445             


His Gly Gly Ala Glu Pro Gly Ala Asp Ser Ala Glu Gly Asp Val Gly 
    450                 455                 460                 


Asp Gly Asp Gly Asp Phe Gly Ala Gly Val Asn Lys Asp Gly Gly Ser 
465                 470                 475                 480 


Arg Val Val Val Gln Met Glu Glu Val Ala Arg Thr Val Asn 
                485                 490                 


<210>  947
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  947

Tyr Ala Leu Thr Gly Gln Lys Trp Gln His Lys His Ile Thr Tyr Ser 
1               5                   10                  15      


Ile Lys Asn Val Thr Pro Lys Val Gly Asp Pro Glu Thr Arg Lys Ala 
            20                  25                  30          


Ile Arg Arg Ala Phe Asp Val Trp Gln Asn Val Thr Pro Leu Thr Phe 
        35                  40                  45              


Glu Glu Val Pro Tyr Ser Glu Leu Glu Asn Gly Lys Arg Asp Val Asp 
    50                  55                  60                  


Ile Thr Ile Ile Phe Ala Ser Gly Phe His Gly Asp Ser Ser Pro Phe 
65                  70                  75                  80  


Asp Gly Glu Gly Gly Phe Leu Ala His Ala Tyr Phe Pro Gly Pro Gly 
                85                  90                  95      


Ile Gly Gly Asp Thr His Phe Asp Ser Asp Glu Pro Trp Thr Leu Gly 
            100                 105                 110         


Asn Pro Asn His Asp Gly Asn Asp Leu Phe Leu Val Ala Val His Glu 
        115                 120                 125             


Leu Gly His Ala Leu Gly Leu Glu His Ser Asn Asp Pro Thr Ala Ile 
    130                 135                 140                 


Met Ala Pro Phe Tyr Gln Tyr Met Glu Thr Asp Asn Phe Lys Leu Pro 
145                 150                 155                 160 


Asn Asp Asp Leu Gln Gly Ile Gln Lys Ile Tyr Gly Pro Pro Asp Lys 
                165                 170                 175     


Ile Pro Pro Pro Thr Arg Pro Leu Pro Thr Val Pro Pro His Arg Ser 
            180                 185                 190         


Ile Pro Pro Ala Asp Pro Arg Lys Asn Asp Arg Pro Lys Pro Pro Arg 
        195                 200                 205             


Pro Pro Thr Gly Arg Pro Ser Tyr Pro Gly Ala Lys Pro Asn Ile Cys 
    210                 215                 220                 


Asp Gly Asn Phe Asn Thr Leu Ala Ile Leu Arg Arg Glu Met Phe Val 
225                 230                 235                 240 


Phe Lys Asp Gln Trp Phe Trp Arg Val Arg Asn Asn Arg Val Met Asp 
                245                 250                 255     


Gly Tyr Pro Met Gln Ile Thr Tyr Phe Trp Arg Gly Leu Pro Pro Ser 
            260                 265                 270         


Ile Asp Ala Val Tyr Glu Asn Ser Asp Gly Asn Phe Val Phe Phe Lys 
        275                 280                 285             


Gly Asn Lys Tyr Trp Val Phe Lys Asp Thr Thr Leu Gln Pro Gly Tyr 
    290                 295                 300                 


Pro His Asp Leu Ile Thr Leu Gly Ser Gly Ile Pro Pro His Gly Ile 
305                 310                 315                 320 


Asp Ser Ala Ile Trp Trp Glu Asp Val Gly Lys Thr Tyr Phe Phe Lys 
                325                 330                 335     


Gly Asp Arg Tyr Trp Arg Tyr Ser Glu Glu Met Lys Thr Met Asp Pro 
            340                 345                 350         


Gly Tyr Pro Lys Pro Ile Thr Val Trp Lys Gly Ile Pro Glu Ser Pro 
        355                 360                 365             


Gln Gly Ala Phe Val His Lys Glu Asn Gly Phe Thr Tyr Phe Tyr Lys 
    370                 375                 380                 


Gly Lys Glu Tyr Trp Lys Phe Asn Asn Gln Ile Leu Lys Val Glu Pro 
385                 390                 395                 400 


Gly Tyr Pro Arg Ser Ile Leu Lys Asp Phe Met Gly Cys Asp Gly Pro 
                405                 410                 415     


Thr Asp Arg Val Lys Glu Gly His Ser Pro Pro Asp Asp Val Asp Ile 
            420                 425                 430         


Val Ile Lys Leu Asp Asn Thr Ala Ser Thr Val Lys Ala 
        435                 440                 445 


<210>  948
<211>  440
<212>  PRT
<213>  Homo Sapiens

<400>  948

Gln Ala Pro Ala Pro Thr Lys Trp Asn Lys Arg Asn Leu Ser Trp Arg 
1               5                   10                  15      


Val Arg Thr Phe Pro Arg Asp Ser Pro Leu Gly His Asp Thr Val Arg 
            20                  25                  30          


Ala Leu Met Tyr Tyr Ala Leu Lys Val Trp Ser Asp Ile Ala Pro Leu 
        35                  40                  45              


Asn Phe His Glu Val Ala Gly Ser Thr Ala Asp Ile Gln Ile Asp Phe 
    50                  55                  60                  


Ser Lys Ala Asn His Asn Asp Gly Tyr Pro Phe Asp Gly Pro Gly Gly 
65                  70                  75                  80  


Thr Val Ala His Ala Phe Phe Pro Gly His His Asn Thr Ala Gly Asp 
                85                  90                  95      


Thr His Phe Asp Asp Asp Glu Ala Trp Thr Phe Arg Ser Ser Asp Ala 
            100                 105                 110         


His Gly Met Asp Leu Phe Ala Val Ala Val His Glu Phe Gly His Ala 
        115                 120                 125             


Ile Gly Leu Ser His Val Ala Ala Ala His Ser Ile Met Arg Pro Tyr 
    130                 135                 140                 


Tyr Gln Gly Pro Val Gly Asp Pro Leu Arg Tyr Gly Leu Pro Tyr Glu 
145                 150                 155                 160 


Asp Lys Val Arg Val Trp Gln Leu Tyr Gly Val Arg Glu Ser Val Ser 
                165                 170                 175     


Pro Thr Ala Gln Pro Glu Glu Pro Pro Leu Leu Pro Glu Pro Pro Asp 
            180                 185                 190         


Asn Arg Ser Ser Ala Pro Pro Arg Lys Asp Val Pro His Arg Cys Ser 
        195                 200                 205             


Thr His Phe Asp Ala Val Ala Gln Ile Arg Gly Glu Ala Phe Phe Phe 
    210                 215                 220                 


Lys Gly Lys Tyr Phe Trp Arg Leu Thr Arg Asp Arg His Leu Val Ser 
225                 230                 235                 240 


Leu Gln Pro Ala Gln Met His Arg Phe Trp Arg Gly Leu Pro Leu His 
                245                 250                 255     


Leu Asp Ser Val Asp Ala Val Tyr Glu Arg Thr Ser Asp His Lys Ile 
            260                 265                 270         


Val Phe Phe Lys Gly Asp Arg Tyr Trp Val Phe Lys Asp Asn Asn Val 
        275                 280                 285             


Glu Glu Gly Tyr Pro Arg Pro Val Ser Asp Phe Ser Leu Pro Pro Gly 
    290                 295                 300                 


Gly Ile Asp Ala Ala Phe Ser Trp Ala His Asn Asp Arg Thr Tyr Phe 
305                 310                 315                 320 


Phe Lys Asp Gln Leu Tyr Trp Arg Tyr Asp Asp His Thr Arg His Met 
                325                 330                 335     


Asp Pro Gly Tyr Pro Ala Gln Ser Pro Leu Trp Arg Gly Val Pro Ser 
            340                 345                 350         


Thr Leu Asp Asp Ala Met Arg Trp Ser Asp Gly Ala Tyr Tyr Phe Phe 
        355                 360                 365             


Arg Gly Gln Glu Tyr Trp Lys Val Leu Asp Gly Glu Leu Glu Val Ala 
    370                 375                 380                 


Pro Gly Tyr Pro Gln Ser Thr Ala Arg Asp Trp Leu Val Cys Gly Asp 
385                 390                 395                 400 


Ser Gln Ala Asp Gly Ser Val Ala Ala Gly Val Asp Ala Ala Glu Gly 
                405                 410                 415     


Pro Arg Ala Pro Pro Gly Gln His Asp Gln Ser Arg Ser Glu Asp Gly 
            420                 425                 430         


Tyr Glu Val Cys Ser Cys Thr Ser 
        435                 440 


<210>  949
<211>  551
<212>  PRT
<213>  Homo Sapiens

<400>  949

Tyr Asn Phe Phe Pro Arg Lys Pro Lys Trp Asp Lys Asn Gln Ile Thr 
1               5                   10                  15      


Tyr Arg Ile Ile Gly Tyr Thr Pro Asp Leu Asp Pro Glu Thr Val Asp 
            20                  25                  30          


Asp Ala Phe Ala Arg Ala Phe Gln Val Trp Ser Asp Val Thr Pro Leu 
        35                  40                  45              


Arg Phe Ser Arg Ile His Asp Gly Glu Ala Asp Ile Met Ile Asn Phe 
    50                  55                  60                  


Gly Arg Trp Glu His Gly Asp Gly Tyr Pro Phe Asp Gly Lys Asp Gly 
65                  70                  75                  80  


Leu Leu Ala His Ala Phe Ala Pro Gly Thr Gly Val Gly Gly Asp Ser 
                85                  90                  95      


His Phe Asp Asp Asp Glu Leu Trp Thr Leu Gly Glu Gly Gln Val Val 
            100                 105                 110         


Arg Val Lys Tyr Gly Asn Ala Asp Gly Glu Tyr Cys Lys Phe Pro Phe 
        115                 120                 125             


Leu Phe Asn Gly Lys Glu Tyr Asn Ser Cys Thr Asp Thr Gly Arg Ser 
    130                 135                 140                 


Asp Gly Phe Leu Trp Cys Ser Thr Thr Tyr Asn Phe Glu Lys Asp Gly 
145                 150                 155                 160 


Lys Tyr Gly Phe Cys Pro His Glu Ala Leu Phe Thr Met Gly Gly Asn 
                165                 170                 175     


Ala Glu Gly Gln Pro Cys Lys Phe Pro Phe Arg Phe Gln Gly Thr Ser 
            180                 185                 190         


Tyr Asp Ser Cys Thr Thr Glu Gly Arg Thr Asp Gly Tyr Arg Trp Cys 
        195                 200                 205             


Gly Thr Thr Glu Asp Tyr Asp Arg Asp Lys Lys Tyr Gly Phe Cys Pro 
    210                 215                 220                 


Glu Thr Ala Met Ser Thr Val Gly Gly Asn Ser Glu Gly Ala Pro Cys 
225                 230                 235                 240 


Val Phe Pro Phe Thr Phe Leu Gly Asn Lys Tyr Glu Ser Cys Thr Ser 
                245                 250                 255     


Ala Gly Arg Ser Asp Gly Lys Met Trp Cys Ala Thr Thr Ala Asn Tyr 
            260                 265                 270         


Asp Asp Asp Arg Lys Trp Gly Phe Cys Pro Asp Gln Gly Tyr Ser Leu 
        275                 280                 285             


Phe Leu Val Ala Ala His Glu Phe Gly His Ala Met Gly Leu Glu His 
    290                 295                 300                 


Ser Gln Asp Pro Gly Ala Leu Met Ala Pro Ile Tyr Thr Tyr Thr Lys 
305                 310                 315                 320 


Asn Phe Arg Leu Ser Gln Asp Asp Ile Lys Gly Ile Gln Glu Leu Tyr 
                325                 330                 335     


Gly Ala Ser Pro Asp Ile Asp Leu Gly Thr Gly Pro Thr Pro Thr Leu 
            340                 345                 350         


Gly Pro Val Thr Pro Glu Ile Cys Lys Gln Asp Ile Val Phe Asp Gly 
        355                 360                 365             


Ile Ala Gln Ile Arg Gly Glu Ile Phe Phe Phe Lys Asp Arg Phe Ile 
    370                 375                 380                 


Trp Arg Thr Val Thr Pro Arg Asp Lys Pro Met Gly Pro Leu Leu Val 
385                 390                 395                 400 


Ala Thr Phe Trp Pro Glu Leu Pro Glu Lys Ile Asp Ala Val Tyr Glu 
                405                 410                 415     


Ala Pro Gln Glu Glu Lys Ala Val Phe Phe Ala Gly Asn Glu Tyr Trp 
            420                 425                 430         


Ile Tyr Ser Ala Ser Thr Leu Glu Arg Gly Tyr Pro Lys Pro Leu Thr 
        435                 440                 445             


Ser Leu Gly Leu Pro Pro Asp Val Gln Arg Val Asp Ala Ala Phe Asn 
    450                 455                 460                 


Trp Ser Lys Asn Lys Lys Thr Tyr Ile Phe Ala Gly Asp Lys Phe Trp 
465                 470                 475                 480 


Arg Tyr Asn Glu Val Lys Lys Lys Met Asp Pro Gly Phe Pro Lys Leu 
                485                 490                 495     


Ile Ala Asp Ala Trp Asn Ala Ile Pro Asp Asn Leu Asp Ala Val Val 
            500                 505                 510         


Asp Leu Gln Gly Gly Gly His Ser Tyr Phe Phe Lys Gly Ala Tyr Tyr 
        515                 520                 525             


Leu Lys Leu Glu Asn Gln Ser Leu Lys Ser Val Lys Phe Gly Ser Ile 
    530                 535                 540                 


Lys Ser Asp Trp Leu Gly Cys 
545                 550     


<210>  950
<211>  426
<212>  PRT
<213>  Homo Sapiens

<400>  950

Tyr Ala Leu Thr Gly Gln Lys Trp Arg Gln Lys His Ile Thr Tyr Ser 
1               5                   10                  15      


Ile His Asn Tyr Thr Pro Lys Val Gly Glu Leu Asp Thr Arg Lys Ala 
            20                  25                  30          


Ile Arg Gln Ala Phe Asp Val Trp Gln Lys Val Thr Pro Leu Thr Phe 
        35                  40                  45              


Glu Glu Val Pro Tyr His Glu Ile Lys Ser Asp Arg Lys Glu Ala Asp 
    50                  55                  60                  


Ile Met Ile Phe Phe Ala Ser Gly Phe His Gly Asp Ser Ser Pro Phe 
65                  70                  75                  80  


Asp Gly Glu Gly Gly Phe Leu Ala His Ala Tyr Phe Pro Gly Pro Gly 
                85                  90                  95      


Ile Gly Gly Asp Thr His Phe Asp Ser Asp Glu Pro Trp Thr Leu Gly 
            100                 105                 110         


Asn Ala Asn His Asp Gly Asn Asp Leu Phe Leu Val Ala Val His Glu 
        115                 120                 125             


Leu Gly His Ala Leu Gly Leu Glu His Ser Ser Asp Pro Ser Ala Ile 
    130                 135                 140                 


Met Ala Pro Phe Tyr Gln Tyr Met Glu Thr His Asn Phe Lys Leu Pro 
145                 150                 155                 160 


Gln Asp Asp Leu Gln Gly Ile Gln Lys Ile Tyr Gly Pro Pro Ala Glu 
                165                 170                 175     


Pro Leu Glu Pro Thr Arg Pro Leu Pro Thr Leu Pro Val Arg Arg Ile 
            180                 185                 190         


His Ser Pro Ser Glu Arg Lys His Glu Arg Gln Pro Arg Pro Pro Arg 
        195                 200                 205             


Pro Pro Leu Gly Asp Arg Pro Ser Thr Pro Gly Thr Lys Pro Asn Ile 
    210                 215                 220                 


Cys Asp Gly Asn Phe Asn Thr Val Ala Leu Phe Arg Gly Glu Met Phe 
225                 230                 235                 240 


Val Phe Lys Asp Arg Trp Phe Trp Arg Leu Arg Asn Asn Arg Val Gln 
                245                 250                 255     


Glu Gly Tyr Pro Met Gln Ile Glu Gln Phe Trp Lys Gly Leu Pro Ala 
            260                 265                 270         


Arg Ile Asp Ala Ala Tyr Glu Arg Ala Asp Gly Arg Phe Val Phe Phe 
        275                 280                 285             


Lys Gly Asp Lys Tyr Trp Val Phe Lys Glu Val Thr Val Glu Pro Gly 
    290                 295                 300                 


Tyr Pro His Ser Leu Gly Glu Leu Gly Ser Cys Leu Pro Arg Glu Gly 
305                 310                 315                 320 


Ile Asp Thr Ala Leu Arg Trp Glu Pro Val Gly Lys Thr Tyr Phe Phe 
                325                 330                 335     


Lys Gly Glu Arg Tyr Trp Arg Tyr Ser Glu Glu Arg Arg Ala Thr Asp 
            340                 345                 350         


Pro Gly Tyr Pro Lys Pro Ile Thr Val Trp Lys Gly Ile Pro Gln Ala 
        355                 360                 365             


Pro Gln Gly Ala Phe Ile Ser Lys Glu Gly Tyr Tyr Thr Tyr Phe Tyr 
    370                 375                 380                 


Lys Gly Arg Asp Tyr Trp Lys Phe Asp Asn Gln Lys Leu Ser Val Glu 
385                 390                 395                 400 


Pro Gly Tyr Pro Arg Asn Ile Leu Arg Asp Trp Met Gly Cys Asn Gln 
                405                 410                 415     


Lys Glu Val Glu Arg Arg Lys Glu Arg Arg 
            420                 425     


<210>  951
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  951

Phe Ala Lys Gln Gly Asn Lys Trp Tyr Lys Gln His Leu Ser Tyr Arg 
1               5                   10                  15      


Leu Val Asn Trp Pro Glu His Leu Pro Glu Pro Ala Val Arg Gly Ala 
            20                  25                  30          


Val Arg Ala Ala Phe Gln Leu Trp Ser Asn Val Ser Ala Leu Glu Phe 
        35                  40                  45              


Trp Glu Ala Pro Ala Thr Gly Pro Ala Asp Ile Arg Leu Thr Phe Phe 
    50                  55                  60                  


Gln Gly Asp His Asn Asp Gly Leu Gly Asn Ala Phe Asp Gly Pro Gly 
65                  70                  75                  80  


Gly Ala Leu Ala His Ala Phe Leu Pro Arg Arg Gly Glu Ala His Phe 
                85                  90                  95      


Asp Gln Asp Glu Arg Trp Ser Leu Ser Arg Arg Arg Gly Arg Asn Leu 
            100                 105                 110         


Phe Val Val Leu Ala His Glu Ile Gly His Thr Leu Gly Leu Thr His 
        115                 120                 125             


Ser Pro Ala Pro Arg Ala Leu Met Ala Pro Tyr Tyr Lys Arg Leu Gly 
    130                 135                 140                 


Arg Asp Ala Leu Leu Ser Trp Asp Asp Val Leu Ala Val Gln Ser Leu 
145                 150                 155                 160 


Tyr Gly Lys Pro Leu Gly Gly Ser Val Ala Val Gln Leu Pro Gly Lys 
                165                 170                 175     


Leu Phe Thr Asp Phe Glu Thr Trp Asp Ser Tyr Ser Pro Gln Gly Arg 
            180                 185                 190         


Arg Pro Glu Thr Gln Gly Pro Lys Tyr Cys His Ser Ser Phe Asp Ala 
        195                 200                 205             


Ile Thr Val Asp Arg Gln Gln Gln Leu Tyr Ile Phe Lys Gly Ser His 
    210                 215                 220                 


Phe Trp Glu Val Ala Ala Asp Gly Asn Val Ser Glu Pro Arg Pro Leu 
225                 230                 235                 240 


Gln Glu Arg Trp Val Gly Leu Pro Pro Asn Ile Glu Ala Ala Ala Val 
                245                 250                 255     


Ser Leu Asn Asp Gly Asp Phe Tyr Phe Phe Lys Val Gln Ser Val 
            260                 265                 270     


<210>  952
<211>  601
<212>  PRT
<213>  Homo Sapiens

<400>  952

Phe Gln Thr Phe Glu Gly Asp Leu Lys Trp His His His Asn Ile Thr 
1               5                   10                  15      


Tyr Trp Ile Gln Asn Tyr Ser Glu Asp Leu Pro Arg Ala Val Ile Asp 
            20                  25                  30          


Asp Ala Phe Ala Arg Ala Phe Ala Leu Trp Ser Ala Val Thr Pro Leu 
        35                  40                  45              


Thr Phe Thr Arg Val Tyr Ser Arg Asp Ala Asp Ile Val Ile Gln Phe 
    50                  55                  60                  


Gly Val Ala Glu His Gly Asp Gly Tyr Pro Phe Asp Gly Lys Asp Gly 
65                  70                  75                  80  


Leu Leu Ala His Ala Phe Pro Pro Gly Pro Gly Ile Gln Gly Asp Ala 
                85                  90                  95      


His Phe Asp Asp Asp Glu Leu Trp Ser Leu Gly Lys Gly Val Val Val 
            100                 105                 110         


Pro Thr Arg Phe Gly Asn Ala Asp Gly Ala Ala Cys His Phe Pro Phe 
        115                 120                 125             


Ile Phe Glu Gly Arg Ser Tyr Ser Ala Cys Thr Thr Asp Gly Arg Ser 
    130                 135                 140                 


Asp Gly Leu Pro Trp Cys Ser Thr Thr Ala Asn Tyr Asp Thr Asp Asp 
145                 150                 155                 160 


Arg Phe Gly Phe Cys Pro Ser Glu Arg Leu Tyr Thr Arg Asp Gly Asn 
                165                 170                 175     


Ala Asp Gly Lys Pro Cys Gln Phe Pro Phe Ile Phe Gln Gly Gln Ser 
            180                 185                 190         


Tyr Ser Ala Cys Thr Thr Asp Gly Arg Ser Asp Gly Tyr Arg Trp Cys 
        195                 200                 205             


Ala Thr Thr Ala Asn Tyr Asp Arg Asp Lys Leu Phe Gly Phe Cys Pro 
    210                 215                 220                 


Thr Arg Ala Asp Ser Thr Val Met Gly Gly Asn Ser Ala Gly Glu Leu 
225                 230                 235                 240 


Cys Val Phe Pro Phe Thr Phe Leu Gly Lys Glu Tyr Ser Thr Cys Thr 
                245                 250                 255     


Ser Glu Gly Arg Gly Asp Gly Arg Leu Trp Cys Ala Thr Thr Ser Asn 
            260                 265                 270         


Phe Asp Ser Asp Lys Lys Trp Gly Phe Cys Pro Asp Gln Gly Tyr Ser 
        275                 280                 285             


Leu Phe Leu Val Ala Ala His Glu Phe Gly His Ala Leu Gly Leu Asp 
    290                 295                 300                 


His Ser Ser Val Pro Glu Ala Leu Met Tyr Pro Met Tyr Arg Phe Thr 
305                 310                 315                 320 


Glu Gly Pro Pro Leu His Lys Asp Asp Val Asn Gly Ile Arg His Leu 
                325                 330                 335     


Tyr Gly Pro Arg Pro Glu Pro Glu Pro Arg Pro Pro Thr Thr Thr Thr 
            340                 345                 350         


Pro Gln Pro Thr Ala Pro Pro Thr Val Cys Pro Thr Gly Pro Pro Thr 
        355                 360                 365             


Val His Pro Ser Glu Arg Pro Thr Ala Gly Pro Thr Gly Pro Pro Ser 
    370                 375                 380                 


Ala Gly Pro Thr Gly Pro Pro Thr Ala Gly Pro Ser Thr Ala Thr Thr 
385                 390                 395                 400 


Val Pro Leu Ser Pro Val Asp Asp Ala Cys Asn Val Asn Ile Phe Asp 
                405                 410                 415     


Ala Ile Ala Glu Ile Gly Asn Gln Leu Tyr Leu Phe Lys Asp Gly Lys 
            420                 425                 430         


Tyr Trp Arg Phe Ser Glu Gly Arg Gly Ser Arg Pro Gln Gly Pro Phe 
        435                 440                 445             


Leu Ile Ala Asp Lys Trp Pro Ala Leu Pro Arg Lys Leu Asp Ser Val 
    450                 455                 460                 


Phe Glu Glu Pro Leu Ser Lys Lys Leu Phe Phe Phe Ser Gly Arg Gln 
465                 470                 475                 480 


Val Trp Val Tyr Thr Gly Ala Ser Val Leu Gly Pro Arg Arg Leu Asp 
                485                 490                 495     


Lys Leu Gly Leu Gly Ala Asp Val Ala Gln Val Thr Gly Ala Leu Arg 
            500                 505                 510         


Ser Gly Arg Gly Lys Met Leu Leu Phe Ser Gly Arg Arg Leu Trp Arg 
        515                 520                 525             


Phe Asp Val Lys Ala Gln Met Val Asp Pro Arg Ser Ala Ser Glu Val 
    530                 535                 540                 


Asp Arg Met Phe Pro Gly Val Pro Leu Asp Thr His Asp Val Phe Gln 
545                 550                 555                 560 


Tyr Arg Glu Lys Ala Tyr Phe Cys Gln Asp Arg Phe Tyr Trp Arg Val 
                565                 570                 575     


Ser Ser Arg Ser Glu Leu Asn Gln Val Asp Gln Val Gly Tyr Val Thr 
            580                 585                 590         


Tyr Asp Ile Leu Gln Cys Pro Glu Asp 
        595                 600     


<210>  953
<211>  1209
<212>  PRT
<213>  Homo Sapiens

<400>  953

Leu Asn Asn Ser Lys His Ser Trp Thr Ile Pro Glu Asp Gly Asn Ser 
1               5                   10                  15      


Gln Lys Thr Met Pro Ser Ala Ser Val Pro Pro Asn Lys Ile Gln Ser 
            20                  25                  30          


Leu Gln Ile Leu Pro Thr Thr Arg Val Met Ser Ala Glu Ile Ala Thr 
        35                  40                  45              


Thr Pro Glu Ala Arg Thr Ser Glu Asp Ser Leu Leu Lys Ser Thr Leu 
    50                  55                  60                  


Pro Pro Ser Glu Thr Ser Ala Pro Ala Glu Gly Val Arg Asn Gln Thr 
65                  70                  75                  80  


Leu Thr Ser Thr Glu Lys Ala Glu Gly Val Val Lys Leu Gln Asn Leu 
                85                  90                  95      


Thr Leu Pro Thr Asn Ala Ser Ile Lys Phe Asn Pro Gly Ala Glu Ser 
            100                 105                 110         


Val Val Leu Ser Asn Ser Thr Leu Lys Phe Leu Gln Ser Phe Ala Arg 
        115                 120                 125             


Lys Ser Asn Glu Gln Ala Thr Ser Leu Asn Thr Val Gly Gly Thr Gly 
    130                 135                 140                 


Gly Ile Gly Gly Val Gly Gly Thr Gly Gly Val Gly Asn Arg Ala Pro 
145                 150                 155                 160 


Arg Glu Thr Tyr Leu Ser Arg Gly Asp Ser Ser Ser Ser Gln Arg Thr 
                165                 170                 175     


Asp Tyr Gln Lys Ser Asn Phe Glu Thr Thr Arg Gly Lys Asn Trp Cys 
            180                 185                 190         


Ala Tyr Val His Thr Arg Leu Ser Pro Thr Val Ile Leu Asp Asn Gln 
        195                 200                 205             


Val Thr Tyr Val Pro Gly Gly Lys Gly Pro Cys Gly Trp Thr Gly Gly 
    210                 215                 220                 


Ser Cys Pro Gln Arg Ser Gln Lys Ile Ser Asn Pro Val Tyr Arg Met 
225                 230                 235                 240 


Gln His Lys Ile Val Thr Ser Leu Asp Trp Arg Cys Cys Pro Gly Tyr 
                245                 250                 255     


Ser Gly Pro Lys Cys Gln Leu Arg Ala Gln Glu Gln Gln Ser Leu Ile 
            260                 265                 270         


His Thr Asn Gln Ala Glu Ser His Thr Ala Val Gly Arg Gly Val Ala 
        275                 280                 285             


Glu Gln Gln Gln Gln Gln Gly Cys Gly Asp Pro Glu Val Met Gln Lys 
    290                 295                 300                 


Met Thr Asp Gln Val Asn Tyr Gln Ala Met Lys Leu Thr Leu Leu Gln 
305                 310                 315                 320 


Lys Lys Ile Asp Asn Ile Ser Leu Thr Val Asn Asp Val Arg Asn Thr 
                325                 330                 335     


Tyr Ser Ser Leu Glu Gly Lys Val Ser Glu Asp Lys Ser Arg Glu Phe 
            340                 345                 350         


Gln Ser Leu Leu Lys Gly Leu Lys Ser Lys Ser Ile Asn Val Leu Ile 
        355                 360                 365             


Arg Asp Ile Val Arg Glu Gln Phe Lys Ile Phe Gln Asn Asp Met Gln 
    370                 375                 380                 


Glu Thr Val Ala Gln Leu Phe Lys Thr Val Ser Ser Leu Ser Glu Asp 
385                 390                 395                 400 


Leu Glu Ser Thr Arg Gln Ile Ile Gln Lys Val Asn Glu Ser Val Val 
                405                 410                 415     


Ser Ile Ala Ala Gln Gln Lys Phe Val Leu Val Gln Glu Asn Arg Pro 
            420                 425                 430         


Thr Leu Thr Asp Ile Val Glu Leu Arg Asn His Ile Val Asn Val Arg 
        435                 440                 445             


Gln Glu Met Thr Leu Thr Cys Glu Lys Pro Ile Lys Glu Leu Glu Val 
    450                 455                 460                 


Lys Gln Thr His Leu Glu Gly Ala Leu Glu Gln Glu His Ser Arg Ser 
465                 470                 475                 480 


Ile Leu Tyr Tyr Glu Ser Leu Asn Lys Thr Leu Ser Lys Leu Lys Glu 
                485                 490                 495     


Val His Glu Gln Leu Leu Ser Thr Glu Gln Val Ser Asp Gln Lys Asn 
            500                 505                 510         


Ala Pro Ala Ala Glu Ser Val Ser Asn Asn Val Thr Glu Tyr Met Ser 
        515                 520                 525             


Thr Leu His Glu Asn Ile Lys Lys Gln Ser Leu Met Met Leu Gln Met 
    530                 535                 540                 


Phe Glu Asp Leu His Ile Gln Glu Ser Lys Ile Asn Asn Leu Thr Val 
545                 550                 555                 560 


Ser Leu Glu Met Glu Lys Glu Ser Leu Arg Gly Glu Cys Glu Asp Met 
                565                 570                 575     


Leu Ser Lys Cys Arg Asn Asp Phe Lys Phe Gln Leu Lys Asp Thr Glu 
            580                 585                 590         


Glu Asn Leu His Val Leu Asn Gln Thr Leu Ala Glu Val Leu Phe Pro 
        595                 600                 605             


Met Asp Asn Lys Met Asp Lys Met Ser Glu Gln Leu Asn Asp Leu Thr 
    610                 615                 620                 


Tyr Asp Met Glu Ile Leu Gln Pro Leu Leu Glu Gln Gly Ala Ser Leu 
625                 630                 635                 640 


Arg Gln Thr Met Thr Tyr Glu Gln Pro Lys Glu Ala Ile Val Ile Arg 
                645                 650                 655     


Lys Lys Ile Glu Asn Leu Thr Ser Ala Val Asn Ser Leu Asn Phe Ile 
            660                 665                 670         


Ile Lys Glu Leu Thr Lys Arg His Asn Leu Leu Arg Asn Glu Val Gln 
        675                 680                 685             


Gly Arg Asp Asp Ala Leu Glu Arg Arg Ile Asn Glu Tyr Ala Leu Glu 
    690                 695                 700                 


Met Glu Asp Gly Leu Asn Lys Thr Met Thr Ile Ile Asn Asn Ala Ile 
705                 710                 715                 720 


Asp Phe Ile Gln Asp Asn Tyr Ala Leu Lys Glu Thr Leu Ser Thr Ile 
                725                 730                 735     


Lys Asp Asn Ser Glu Ile His His Lys Cys Thr Ser Asp Met Glu Thr 
            740                 745                 750         


Ile Leu Thr Phe Ile Pro Gln Phe His Arg Leu Asn Asp Ser Ile Gln 
        755                 760                 765             


Thr Leu Val Asn Asp Asn Gln Arg Tyr Asn Phe Val Leu Gln Val Ala 
    770                 775                 780                 


Lys Thr Leu Ala Gly Ile Pro Arg Asp Glu Lys Leu Asn Gln Ser Asn 
785                 790                 795                 800 


Phe Gln Lys Met Tyr Gln Met Phe Asn Glu Thr Thr Ser Gln Val Arg 
                805                 810                 815     


Lys Tyr Gln Gln Asn Met Ser His Leu Glu Glu Lys Leu Leu Leu Thr 
            820                 825                 830         


Thr Lys Ile Ser Lys Asn Phe Glu Thr Arg Leu Gln Asp Ile Glu Ser 
        835                 840                 845             


Lys Val Thr Gln Thr Leu Ile Pro Tyr Tyr Ile Ser Val Lys Lys Gly 
    850                 855                 860                 


Ser Val Val Thr Asn Glu Arg Asp Gln Ala Leu Gln Leu Gln Val Leu 
865                 870                 875                 880 


Asn Ser Arg Phe Lys Ala Leu Glu Ala Lys Ser Ile His Leu Ser Ile 
                885                 890                 895     


Asn Phe Phe Ser Leu Asn Lys Thr Leu His Glu Val Leu Thr Met Cys 
            900                 905                 910         


His Asn Ala Ser Thr Ser Val Ser Glu Leu Asn Ala Thr Ile Pro Lys 
        915                 920                 925             


Trp Ile Lys His Ser Leu Pro Asp Ile Gln Leu Leu Gln Lys Gly Leu 
    930                 935                 940                 


Arg Glu Phe Val Glu Pro Ile Ile Gln Ile Lys Thr Gln Ala Ala Leu 
945                 950                 955                 960 


Ser Asn Leu Thr Cys Cys Ile Asp Arg Ser Leu Pro Gly Ser Leu Ala 
                965                 970                 975     


Asn Val Val Lys Ser Gln Lys Gln Val Lys Ser Leu Pro Lys Lys Ile 
            980                 985                 990         


Asn Ala Leu Lys Lys Pro Thr Val  Asn Leu Thr Thr Val  Leu Ile Gly 
        995                 1000                 1005             


Arg Thr  Gln Arg Asn Thr Asp  Asn Ile Ile Tyr Pro  Glu Glu Tyr 
    1010                 1015                 1020             


Ser Ser  Cys Ser Arg His Pro  Cys Gln Asn Gly Gly  Thr Cys Ile 
    1025                 1030                 1035             


Asn Gly  Arg Thr Ser Phe Thr  Cys Ala Cys Arg His  Pro Phe Thr 
    1040                 1045                 1050             


Gly Asp  Asn Cys Thr Ile Lys  Leu Val Glu Glu Asn  Ala Leu Ala 
    1055                 1060                 1065             


Pro Asp  Phe Ser Lys Gly Ser  Tyr Arg Tyr Ala Pro  Met Val Ala 
    1070                 1075                 1080             


Phe Phe  Ala Ser His Thr Tyr  Gly Met Thr Ile Pro  Gly Pro Ile 
    1085                 1090                 1095             


Leu Phe  Asn Asn Leu Asp Val  Asn Tyr Gly Ala Ser  Tyr Thr Pro 
    1100                 1105                 1110             


Arg Thr  Gly Lys Phe Arg Ile  Pro Tyr Leu Gly Val  Tyr Val Phe 
    1115                 1120                 1125             


Lys Tyr  Thr Ile Glu Ser Phe  Ser Ala His Ile Ser  Gly Phe Leu 
    1130                 1135                 1140             


Val Val  Asp Gly Ile Asp Lys  Leu Ala Phe Glu Ser  Glu Asn Ile 
    1145                 1150                 1155             


Asn Ser  Glu Ile His Cys Asp  Arg Val Leu Thr Gly  Asp Ala Leu 
    1160                 1165                 1170             


Leu Glu  Leu Asn Tyr Gly Gln  Glu Val Trp Leu Arg  Leu Ala Lys 
    1175                 1180                 1185             


Gly Thr  Ile Pro Ala Lys Phe  Pro Pro Val Thr Thr  Phe Ser Gly 
    1190                 1195                 1200             


Tyr Leu  Leu Tyr Arg Thr 
    1205                 


<210>  954
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  954

Gly Gln Phe Arg Val Ile Gly Pro Arg His Pro Ile Arg Ala Leu Val 
1               5                   10                  15      


Gly Asp Glu Val Glu Leu Pro Cys Arg Ile Ser Pro Gly Lys Asn Ala 
            20                  25                  30          


Thr Gly Met Glu Val Gly Trp Tyr Arg Pro Pro Phe Ser Arg Val Val 
        35                  40                  45              


His Leu Tyr Arg Asn Gly Lys Asp Gln Asp Gly Asp Gln Ala Pro Glu 
    50                  55                  60                  


Tyr Arg Gly Arg Thr Glu Leu Leu Lys Asp Ala Ile Gly Glu Gly Lys 
65                  70                  75                  80  


Val Thr Leu Arg Ile Arg Asn Val Arg Phe Ser Asp Glu Gly Gly Phe 
                85                  90                  95      


Thr Cys Phe Phe Arg Asp His Ser Tyr Gln Glu Glu Ala Ala Met Glu 
            100                 105                 110         


Leu Lys Val Glu Asp Pro Phe Tyr Trp Val Ser Pro Gly 
        115                 120                 125 


<210>  955
<211>  466
<212>  PRT
<213>  Homo Sapiens

<400>  955

Gln Asp Val Ser Leu Leu Ala Ser Asp Ser Glu Pro Leu Lys Cys Phe 
1               5                   10                  15      


Ser Arg Thr Phe Glu Asp Leu Thr Cys Phe Trp Asp Glu Glu Glu Ala 
            20                  25                  30          


Ala Pro Ser Gly Thr Tyr Gln Leu Leu Tyr Ala Tyr Pro Arg Glu Lys 
        35                  40                  45              


Pro Arg Ala Cys Pro Leu Ser Ser Gln Ser Met Pro His Phe Gly Thr 
    50                  55                  60                  


Arg Tyr Val Cys Gln Phe Pro Asp Gln Glu Glu Val Arg Leu Phe Phe 
65                  70                  75                  80  


Pro Leu His Leu Trp Val Lys Asn Val Phe Leu Asn Gln Thr Arg Thr 
                85                  90                  95      


Gln Arg Val Leu Phe Val Asp Ser Val Gly Leu Pro Ala Pro Pro Ser 
            100                 105                 110         


Ile Ile Lys Ala Met Gly Gly Ser Gln Pro Gly Glu Leu Gln Ile Ser 
        115                 120                 125             


Trp Glu Glu Pro Ala Pro Glu Ile Ser Asp Phe Leu Arg Tyr Glu Leu 
    130                 135                 140                 


Arg Tyr Gly Pro Arg Asp Pro Lys Asn Ser Thr Gly Pro Thr Val Ile 
145                 150                 155                 160 


Gln Leu Ile Ala Thr Glu Thr Cys Cys Pro Ala Leu Gln Arg Pro His 
                165                 170                 175     


Ser Ala Ser Ala Leu Asp Gln Ser Pro Cys Ala Gln Pro Thr Met Pro 
            180                 185                 190         


Trp Gln Asp Gly Pro Lys Gln Thr Ser Pro Ser Arg Glu Ala Ser Ala 
        195                 200                 205             


Leu Thr Ala Glu Gly Gly Ser Cys Leu Ile Ser Gly Leu Gln Pro Gly 
    210                 215                 220                 


Asn Ser Tyr Trp Leu Gln Leu Arg Ser Glu Pro Asp Gly Ile Ser Leu 
225                 230                 235                 240 


Gly Gly Ser Trp Gly Ser Trp Ser Leu Pro Val Thr Val Asp Leu Pro 
                245                 250                 255     


Gly Asp Ala Val Ala Leu Gly Leu Gln Cys Phe Thr Leu Asp Leu Lys 
            260                 265                 270         


Asn Val Thr Cys Gln Trp Gln Gln Gln Asp His Ala Ser Ser Gln Gly 
        275                 280                 285             


Phe Phe Tyr His Ser Arg Ala Arg Cys Cys Pro Arg Asp Arg Tyr Pro 
    290                 295                 300                 


Ile Trp Glu Asn Cys Glu Glu Glu Glu Lys Thr Asn Pro Gly Leu Gln 
305                 310                 315                 320 


Thr Pro Gln Phe Ser Arg Cys His Phe Lys Ser Arg Asn Asp Ser Ile 
                325                 330                 335     


Ile His Ile Leu Val Glu Val Thr Thr Ala Pro Gly Thr Val His Ser 
            340                 345                 350         


Tyr Leu Gly Ser Pro Phe Trp Ile His Gln Ala Val Arg Leu Pro Thr 
        355                 360                 365             


Pro Asn Leu His Trp Arg Glu Ile Ser Ser Gly His Leu Glu Leu Glu 
    370                 375                 380                 


Trp Gln His Pro Ser Ser Trp Ala Ala Gln Glu Thr Cys Tyr Gln Leu 
385                 390                 395                 400 


Arg Tyr Thr Gly Glu Gly His Gln Asp Trp Lys Val Leu Glu Pro Pro 
                405                 410                 415     


Leu Gly Ala Arg Gly Gly Thr Leu Glu Leu Arg Pro Arg Ser Arg Tyr 
            420                 425                 430         


Arg Leu Gln Leu Arg Ala Arg Leu Asn Gly Pro Thr Tyr Gln Gly Pro 
        435                 440                 445             


Trp Ser Ser Trp Ser Asp Pro Thr Arg Val Glu Thr Ala Thr Glu Thr 
    450                 455                 460                 


Ala Trp 
465     


<210>  956
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  956

Ile Val Val Tyr Thr Asp Arg Glu Val His Gly Ala Val Gly Ser Arg 
1               5                   10                  15      


Val Thr Leu His Cys Ser Phe Trp Ser Ser Glu Trp Val Ser Asp Asp 
            20                  25                  30          


Ile Ser Phe Thr Trp Arg Tyr Gln Pro Glu Gly Gly Arg Asp Ala Ile 
        35                  40                  45              


Ser Ile Phe His Tyr Ala Lys Gly Gln Pro Tyr Ile Asp Glu Val Gly 
    50                  55                  60                  


Thr Phe Lys Glu Arg Ile Gln Trp Val Gly Asp Pro Arg Trp Lys Asp 
65                  70                  75                  80  


Gly Ser Ile Val Ile His Asn Leu Asp Tyr Ser Asp Asn Gly Thr Phe 
                85                  90                  95      


Thr Cys Asp Val Lys Asn Pro Pro Asp Ile Val Gly Lys Thr Ser Gln 
            100                 105                 110         


Val Thr Leu Tyr Val Phe Glu Lys Val Pro Thr Arg 
        115                 120                 


<210>  957
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  957

Ser Ala Leu Glu Val Tyr Thr Pro Lys Glu Ile Phe Val Ala Asn Gly 
1               5                   10                  15      


Thr Gln Gly Lys Leu Thr Cys Lys Phe Lys Ser Thr Ser Thr Thr Gly 
            20                  25                  30          


Gly Leu Thr Ser Val Ser Trp Ser Phe Gln Pro Glu Gly Ala Asp Thr 
        35                  40                  45              


Thr Val Ser Phe Phe His Tyr Ser Gln Gly Gln Val Tyr Leu Gly Asn 
    50                  55                  60                  


Tyr Pro Pro Phe Lys Asp Arg Ile Ser Trp Ala Gly Asp Leu Asp Lys 
65                  70                  75                  80  


Lys Asp Ala Ser Ile Asn Ile Glu Asn Met Gln Phe Ile His Asn Gly 
                85                  90                  95      


Thr Tyr Ile Cys Asp Val Lys Asn Pro Pro Asp Ile Val Val Gln Pro 
            100                 105                 110         


Gly His Ile Arg Leu Tyr Val Val Glu Lys Glu Asn Leu Pro Val 
        115                 120                 125         


<210>  958
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  958

Val Glu Ile Tyr Thr Ser Arg Val Leu Glu Ala Val Asn Gly Thr Asp 
1               5                   10                  15      


Ala Arg Leu Lys Cys Thr Phe Ser Ser Phe Ala Pro Val Gly Asp Ala 
            20                  25                  30          


Leu Thr Val Thr Trp Asn Phe Arg Pro Leu Asp Gly Gly Pro Glu Gln 
        35                  40                  45              


Phe Val Phe Tyr Tyr His Ile Asp Pro Phe Gln Pro Met Ser Gly Arg 
    50                  55                  60                  


Phe Lys Asp Arg Val Ser Trp Asp Gly Asn Pro Glu Arg Tyr Asp Ala 
65                  70                  75                  80  


Ser Ile Leu Leu Trp Lys Leu Gln Phe Asp Asp Asn Gly Thr Tyr Thr 
                85                  90                  95      


Cys Gln Val Lys Asn Pro Pro Asp Val Asp Gly Val Ile Gly Glu Ile 
            100                 105                 110         


Arg Leu Ser Val Val His Thr Val Arg Phe Ser Glu Ile His Phe Leu 
        115                 120                 125             


<210>  959
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  959

Leu Glu Ile Arg Ala Asp Ala His Val Arg Gly Tyr Val Gly Glu Lys 
1               5                   10                  15      


Ile Lys Leu Lys Cys Thr Phe Lys Ser Thr Ser Asp Val Thr Asp Lys 
            20                  25                  30          


Leu Thr Ile Asp Trp Thr Tyr Arg Pro Pro Ser Ser Ser His Thr Val 
        35                  40                  45              


Ser Ile Phe His Tyr Gln Ser Phe Gln Tyr Pro Thr Thr Ala Gly Thr 
    50                  55                  60                  


Phe Arg Asp Arg Ile Ser Trp Val Gly Asn Val Tyr Lys Gly Asp Ala 
65                  70                  75                  80  


Ser Ile Ser Ile Ser Asn Pro Thr Ile Lys Asp Asn Gly Thr Phe Ser 
                85                  90                  95      


Cys Ala Val Lys Asn Pro Pro Asp Val His His Asn Ile Pro Met Thr 
            100                 105                 110         


Glu Leu Thr Val Thr Glu Arg Gly Phe Gly Thr Met Leu Ser Ser 
        115                 120                 125         


<210>  960
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  960

Arg Thr His Ser Leu Arg Tyr Phe Arg Leu Gly Val Ser Asp Pro Ile 
1               5                   10                  15      


His Gly Val Pro Glu Phe Ile Ser Val Gly Tyr Val Asp Ser His Pro 
            20                  25                  30          


Ile Thr Thr Tyr Asp Ser Val Thr Arg Gln Lys Glu Pro Arg Ala Pro 
        35                  40                  45              


Trp Met Ala Glu Asn Leu Ala Pro Asp His Trp Glu Arg Tyr Thr Gln 
    50                  55                  60                  


Leu Leu Arg Gly Trp Gln Gln Met Phe Lys Val Glu Leu Lys Arg Leu 
65                  70                  75                  80  


Gln Arg His Tyr Asn His Ser Asp Asn Val Ala His Thr Ile Lys Gln 
                85                  90                  95      


Ala Trp Glu Ala Asn Gln His Glu Leu Leu Tyr Gln Lys Asn Trp Leu 
            100                 105                 110         


Glu Glu Glu Cys Ile Ala Trp Leu Lys Arg Phe Leu Glu Tyr Gly Lys 
        115                 120                 125             


Asp Thr Leu Gln Arg Thr Glu Pro Pro Leu Val Arg Val Asn Arg Lys 
    130                 135                 140                 


Glu Thr Phe Pro Gly Val Thr Ala Leu Phe Cys Lys Ala His Gly Phe 
145                 150                 155                 160 


Tyr Pro Pro Glu Ile Tyr Met Thr Trp Met Lys Asn Gly Glu Glu Ile 
                165                 170                 175     


Val Gln Glu Ile Asp Tyr Gly Asp Ile Leu Pro Ser Gly Asp Gly Thr 
            180                 185                 190         


Tyr Gln Ala Trp Ala Ser Ile Glu Leu Asp Pro Gln Ser Ser Asn Leu 
        195                 200                 205             


Tyr Ser Cys His Val Glu His Cys Gly Val His Met Val Leu Gln Val 
    210                 215                 220                 


Pro Gln Glu Ser Glu Thr Ile Pro Leu Val Met 
225                 230                 235 


<210>  961
<211>  480
<212>  PRT
<213>  Homo Sapiens

<400>  961

Leu Leu Asp Thr Arg Gln Phe Leu Ile Tyr Asn Glu Asp His Lys Arg 
1               5                   10                  15      


Cys Val Asp Ala Val Ser Pro Ser Ala Val Gln Thr Ala Ala Cys Asn 
            20                  25                  30          


Gln Asp Ala Glu Ser Gln Lys Phe Arg Trp Val Ser Glu Ser Gln Ile 
        35                  40                  45              


Met Ser Val Ala Phe Lys Leu Cys Leu Gly Val Pro Ser Lys Thr Asp 
    50                  55                  60                  


Trp Val Ala Ile Thr Leu Tyr Ala Cys Asp Ser Lys Ser Glu Phe Gln 
65                  70                  75                  80  


Lys Trp Glu Cys Lys Asn Asp Thr Leu Leu Gly Ile Lys Gly Glu Asp 
                85                  90                  95      


Leu Phe Phe Asn Tyr Gly Asn Arg Gln Glu Lys Asn Ile Met Leu Tyr 
            100                 105                 110         


Lys Gly Ser Gly Leu Trp Ser Arg Trp Lys Ile Tyr Gly Thr Thr Asp 
        115                 120                 125             


Asn Leu Cys Ser Arg Gly Tyr Glu Ala Met Tyr Thr Leu Leu Gly Asn 
    130                 135                 140                 


Ala Asn Gly Ala Thr Cys Ala Phe Pro Phe Lys Phe Glu Asn Lys Trp 
145                 150                 155                 160 


Tyr Ala Asp Cys Thr Ser Ala Gly Arg Ser Asp Gly Trp Leu Trp Cys 
                165                 170                 175     


Gly Thr Thr Thr Asp Tyr Asp Thr Asp Lys Leu Phe Gly Tyr Cys Pro 
            180                 185                 190         


Leu Lys Phe Glu Gly Ser Glu Ser Leu Trp Asn Lys Asp Pro Leu Thr 
        195                 200                 205             


Ser Val Ser Tyr Gln Ile Asn Ser Lys Ser Ala Leu Thr Trp His Gln 
    210                 215                 220                 


Ala Arg Lys Ser Cys Gln Gln Gln Asn Ala Glu Leu Leu Ser Ile Thr 
225                 230                 235                 240 


Glu Ile His Glu Gln Thr Tyr Leu Thr Gly Leu Thr Ser Ser Leu Thr 
                245                 250                 255     


Ser Gly Leu Trp Ile Gly Leu Asn Ser Leu Ser Phe Asn Ser Gly Trp 
            260                 265                 270         


Gln Trp Ser Asp Arg Ser Pro Phe Arg Tyr Leu Asn Trp Leu Pro Gly 
        275                 280                 285             


Ser Pro Ser Ala Glu Pro Gly Lys Ser Cys Val Ser Leu Asn Pro Gly 
    290                 295                 300                 


Lys Asn Ala Lys Trp Glu Asn Leu Glu Cys Val Gln Lys Leu Gly Tyr 
305                 310                 315                 320 


Ile Cys Lys Lys Gly Asn Thr Thr Leu Asn Ser Phe Val Ile Pro Ser 
                325                 330                 335     


Glu Ser Asp Val Pro Thr His Cys Pro Ser Gln Trp Trp Pro Tyr Ala 
            340                 345                 350         


Gly His Cys Tyr Lys Ile His Arg Asp Glu Lys Lys Ile Gln Arg Asp 
        355                 360                 365             


Ala Leu Thr Thr Cys Arg Lys Glu Gly Ser Asp Leu Ala Ser Ile His 
    370                 375                 380                 


Thr Ile Glu Glu Phe Asp Phe Ile Ile Ser Gln Leu Gly Tyr Glu Pro 
385                 390                 395                 400 


Asn Asp Glu Leu Trp Ile Gly Leu Asn Asp Ile Lys Ile Gln Met Tyr 
                405                 410                 415     


Phe Glu Trp Ser Asp Gly Thr Pro Val Thr Phe Thr Lys Trp Leu Arg 
            420                 425                 430         


Gly Glu Pro Ser His Glu Asn Asn Arg Gln Glu Asp Cys Val Val Met 
        435                 440                 445             


Lys Gly Lys Ala Gly Val Gln Trp His Asn Leu Gly Ser Met Gln Pro 
    450                 455                 460                 


Leu Pro Arg Glu Phe Lys Arg Phe Ser Cys Leu Ser Leu Pro Ser Ser 
465                 470                 475                 480 


<210>  962
<211>  1384
<212>  PRT
<213>  Homo Sapiens

<400>  962

Gly Ala Pro Gly Asp Ala Ala Leu Pro Glu Pro Asn Val Phe Leu Ile 
1               5                   10                  15      


Phe Ser His Gly Leu Gln Gly Cys Leu Glu Ala Gln Gly Gly Gln Val 
            20                  25                  30          


Arg Val Thr Pro Ala Cys Asn Thr Ser Leu Pro Ala Gln Arg Trp Lys 
        35                  40                  45              


Trp Val Ser Arg Asn Arg Leu Phe Asn Leu Gly Thr Met Gln Cys Leu 
    50                  55                  60                  


Gly Thr Gly Trp Pro Gly Thr Asn Thr Thr Ala Ser Leu Gly Met Tyr 
65                  70                  75                  80  


Glu Cys Asp Arg Glu Ala Leu Asn Leu Arg Trp His Cys Arg Thr Leu 
                85                  90                  95      


Gly Asp Gln Leu Ser Leu Leu Leu Gly Ala Arg Thr Ser Asn Ile Ser 
            100                 105                 110         


Lys Pro Gly Thr Leu Glu Arg Gly Asp Gln Thr Arg Ser Gly Gln Trp 
        115                 120                 125             


Arg Ile Tyr Gly Ser Glu Glu Asp Leu Cys Ala Leu Pro Tyr His Glu 
    130                 135                 140                 


Val Tyr Thr Ile Gln Gly Asn Ser His Gly Lys Pro Cys Thr Ile Pro 
145                 150                 155                 160 


Phe Lys Tyr Asp Asn Gln Trp Phe His Gly Cys Thr Ser Thr Gly Arg 
                165                 170                 175     


Glu Asp Gly His Leu Trp Cys Ala Thr Thr Gln Asp Tyr Gly Lys Asp 
            180                 185                 190         


Glu Arg Trp Gly Phe Cys Pro Ile Lys Ser Asn Asp Cys Glu Thr Phe 
        195                 200                 205             


Trp Asp Lys Asp Gln Leu Thr Asp Ser Cys Tyr Gln Phe Asn Phe Gln 
    210                 215                 220                 


Ser Thr Leu Ser Trp Arg Glu Ala Trp Ala Ser Cys Glu Gln Gln Gly 
225                 230                 235                 240 


Ala Asp Leu Leu Ser Ile Thr Glu Ile His Glu Gln Thr Tyr Ile Asn 
                245                 250                 255     


Gly Leu Leu Thr Gly Tyr Ser Ser Thr Leu Trp Ile Gly Leu Asn Asp 
            260                 265                 270         


Leu Asp Thr Ser Gly Gly Trp Gln Trp Ser Asp Asn Ser Pro Leu Lys 
        275                 280                 285             


Tyr Leu Asn Trp Glu Ser Asp Gln Pro Asp Asn Pro Ser Glu Glu Asn 
    290                 295                 300                 


Cys Gly Val Ile Arg Thr Glu Ser Ser Gly Gly Trp Gln Asn Arg Asp 
305                 310                 315                 320 


Cys Ser Ile Ala Leu Pro Tyr Val Cys Lys Lys Lys Pro Asn Ala Thr 
                325                 330                 335     


Ala Glu Pro Thr Pro Pro Asp Arg Trp Ala Asn Val Lys Val Glu Cys 
            340                 345                 350         


Glu Pro Ser Trp Gln Pro Phe Gln Gly His Cys Tyr Arg Leu Gln Ala 
        355                 360                 365             


Glu Lys Arg Ser Trp Gln Glu Ser Lys Lys Ala Cys Leu Arg Gly Gly 
    370                 375                 380                 


Gly Asp Leu Val Ser Ile His Ser Met Ala Glu Leu Glu Phe Ile Thr 
385                 390                 395                 400 


Lys Gln Ile Lys Gln Glu Val Glu Glu Leu Trp Ile Gly Leu Asn Asp 
                405                 410                 415     


Leu Lys Leu Gln Met Asn Phe Glu Trp Ser Asp Gly Ser Leu Val Ser 
            420                 425                 430         


Phe Thr His Trp His Pro Phe Glu Pro Asn Asn Phe Arg Asp Ser Leu 
        435                 440                 445             


Glu Asp Cys Val Thr Ile Trp Gly Pro Glu Gly Arg Trp Asn Asp Ser 
    450                 455                 460                 


Pro Cys Asn Gln Ser Leu Pro Ser Ile Cys Lys Lys Ala Gly Gln Leu 
465                 470                 475                 480 


Ser Gln Gly Ala Ala Glu Glu Asp His Gly Cys Arg Lys Gly Trp Thr 
                485                 490                 495     


Trp His Ser Pro Ser Cys Tyr Trp Leu Gly Glu Asp Gln Val Thr Tyr 
            500                 505                 510         


Ser Glu Ala Arg Arg Leu Cys Thr Asp His Gly Ser Gln Leu Val Thr 
        515                 520                 525             


Ile Thr Asn Arg Phe Glu Gln Ala Phe Val Ser Ser Leu Ile Tyr Asn 
    530                 535                 540                 


Trp Glu Gly Glu Tyr Phe Trp Thr Ala Leu Gln Asp Leu Asn Ser Thr 
545                 550                 555                 560 


Gly Ser Phe Phe Trp Leu Ser Gly Asp Glu Val Met Tyr Thr His Trp 
                565                 570                 575     


Asn Arg Asp Gln Pro Gly Tyr Ser Arg Gly Gly Cys Val Ala Leu Ala 
            580                 585                 590         


Thr Gly Ser Ala Met Gly Leu Trp Glu Val Lys Asn Cys Thr Ser Phe 
        595                 600                 605             


Arg Ala Arg Tyr Ile Cys Arg Gln Ser Leu Gly Thr Pro Val Thr Pro 
    610                 615                 620                 


Glu Leu Pro Gly Pro Asp Pro Thr Pro Ser Leu Thr Gly Ser Cys Pro 
625                 630                 635                 640 


Gln Gly Trp Ala Ser Asp Thr Lys Leu Arg Tyr Cys Tyr Lys Val Phe 
                645                 650                 655     


Ser Ser Glu Arg Leu Gln Asp Lys Lys Ser Trp Val Gln Ala Gln Gly 
            660                 665                 670         


Ala Cys Gln Glu Leu Gly Ala Gln Leu Leu Ser Leu Ala Ser Tyr Glu 
        675                 680                 685             


Glu Glu His Phe Val Ala Asn Met Leu Asn Lys Ile Phe Gly Glu Ser 
    690                 695                 700                 


Glu Pro Glu Ile His Glu Gln His Trp Phe Trp Ile Gly Leu Asn Arg 
705                 710                 715                 720 


Arg Asp Pro Arg Gly Gly Gln Ser Trp Arg Trp Ser Asp Gly Val Gly 
                725                 730                 735     


Phe Ser Tyr His Asn Phe Asp Arg Ser Arg His Asp Asp Asp Asp Ile 
            740                 745                 750         


Arg Gly Cys Ala Val Leu Asp Leu Ala Ser Leu Gln Trp Val Ala Met 
        755                 760                 765             


Gln Cys Asp Thr Gln Leu Asp Trp Ile Cys Lys Ile Pro Arg Gly Thr 
    770                 775                 780                 


Asp Val Arg Glu Pro Asp Asp Ser Pro Gln Gly Arg Arg Glu Trp Leu 
785                 790                 795                 800 


Arg Phe Gln Glu Ala Glu Tyr Lys Phe Phe Glu His His Ser Thr Trp 
                805                 810                 815     


Ala Gln Ala Gln Arg Ile Cys Thr Trp Phe Gln Ala Glu Leu Thr Ser 
            820                 825                 830         


Val His Ser Gln Ala Glu Leu Asp Phe Leu Ser His Asn Leu Gln Lys 
        835                 840                 845             


Phe Ser Arg Ala Gln Glu Gln His Trp Trp Ile Gly Leu His Thr Ser 
    850                 855                 860                 


Glu Ser Asp Gly Arg Phe Arg Trp Thr Asp Gly Ser Ile Ile Asn Phe 
865                 870                 875                 880 


Ile Ser Trp Ala Pro Gly Lys Pro Arg Pro Val Gly Lys Asp Lys Lys 
                885                 890                 895     


Cys Val Tyr Met Thr Ala Ser Arg Glu Asp Trp Gly Asp Gln Arg Cys 
            900                 905                 910         


Leu Thr Ala Leu Pro Tyr Ile Cys Lys Arg Ser Asn Val Thr Lys Glu 
        915                 920                 925             


Thr Gln Pro Pro Asp Leu Pro Thr Thr Ala Leu Gly Gly Cys Pro Ser 
    930                 935                 940                 


Asp Trp Ile Gln Phe Leu Asn Lys Cys Phe Gln Val Gln Gly Gln Glu 
945                 950                 955                 960 


Pro Gln Ser Arg Val Lys Trp Ser Glu Ala Gln Phe Ser Cys Glu Gln 
                965                 970                 975     


Gln Glu Ala Gln Leu Val Thr Ile Thr Asn Pro Leu Glu Gln Ala Phe 
            980                 985                 990         


Ile Thr Ala Ser Leu Pro Asn Val  Thr Phe Asp Leu Trp  Ile Gly Leu 
        995                 1000                 1005             


His Ala  Ser Gln Arg Asp Phe  Gln Trp Val Glu Gln  Glu Pro Leu 
    1010                 1015                 1020             


Met Tyr  Ala Asn Trp Ala Pro  Gly Glu Pro Ser Gly  Pro Ser Pro 
    1025                 1030                 1035             


Ala Pro  Ser Gly Asn Lys Pro  Thr Ser Cys Ala Val  Val Leu His 
    1040                 1045                 1050             


Ser Pro  Ser Ala His Phe Thr  Gly Arg Trp Asp Asp  Arg Ser Cys 
    1055                 1060                 1065             


Thr Glu  Glu Thr His Gly Phe  Ile Cys Gln Lys Gly  Thr Asp Pro 
    1070                 1075                 1080             


Ser Leu  Ser Pro Ser Pro Ala  Ala Leu Pro Pro Ala  Pro Gly Thr 
    1085                 1090                 1095             


Glu Leu  Ser Tyr Leu Asn Gly  Thr Phe Arg Leu Leu  Gln Lys Pro 
    1100                 1105                 1110             


Leu Arg  Trp His Asp Ala Leu  Leu Leu Cys Glu Ser  His Asn Ala 
    1115                 1120                 1125             


Ser Leu  Ala Tyr Val Pro Asp  Pro Tyr Thr Gln Ala  Phe Leu Thr 
    1130                 1135                 1140             


Gln Ala  Ala Arg Gly Leu Arg  Thr Pro Leu Trp Ile  Gly Leu Ala 
    1145                 1150                 1155             


Gly Glu  Glu Gly Ser Arg Arg  Tyr Ser Trp Val Ser  Glu Glu Pro 
    1160                 1165                 1170             


Leu Asn  Tyr Val Gly Trp Gln  Asp Gly Glu Pro Gln  Gln Pro Gly 
    1175                 1180                 1185             


Gly Cys  Thr Tyr Val Asp Val  Asp Gly Ala Trp Arg  Thr Thr Ser 
    1190                 1195                 1200             


Cys Asp  Thr Lys Leu Gln Gly  Ala Val Cys Gly Val  Ser Ser Gly 
    1205                 1210                 1215             


Pro Pro  Pro Pro Arg Arg Ile  Ser Tyr His Gly Ser  Cys Pro Gln 
    1220                 1225                 1230             


Gly Leu  Ala Asp Ser Ala Trp  Ile Pro Phe Arg Glu  His Cys Tyr 
    1235                 1240                 1245             


Ser Phe  His Met Glu Leu Leu  Leu Gly His Lys Glu  Ala Arg Gln 
    1250                 1255                 1260             


Arg Cys  Gln Arg Ala Gly Gly  Ala Val Leu Ser Ile  Leu Asp Glu 
    1265                 1270                 1275             


Met Glu  Asn Val Phe Val Trp  Glu His Leu Gln Ser  Tyr Glu Gly 
    1280                 1285                 1290             


Gln Ser  Arg Gly Ala Trp Leu  Gly Met Asn Phe Asn  Pro Lys Gly 
    1295                 1300                 1305             


Gly Thr  Leu Val Trp Gln Asp  Asn Thr Ala Val Asn  Tyr Ser Asn 
    1310                 1315                 1320             


Trp Gly  Pro Pro Gly Leu Gly  Pro Ser Met Leu Ser  His Asn Ser 
    1325                 1330                 1335             


Cys Tyr  Trp Ile Gln Ser Asn  Ser Gly Leu Trp Arg  Pro Gly Ala 
    1340                 1345                 1350             


Cys Thr  Asn Ile Thr Met Gly  Val Val Cys Lys Leu  Pro Arg Ala 
    1355                 1360                 1365             


Glu Gln  Ser Ser Phe Ser Pro  Ser Ala Leu Pro Glu  Asn Pro Ala 
    1370                 1375                 1380             


Ala 
    


<210>  963
<211>  375
<212>  PRT
<213>  Homo Sapiens

<400>  963

Lys Trp Glu Thr Lys Asn Cys Ser Val Ser Ser Thr Asn Ala Asn Asp 
1               5                   10                  15      


Ile Thr Gln Ser Leu Thr Gly Lys Gly Asn Asp Ser Glu Glu Glu Met 
            20                  25                  30          


Arg Phe Gln Glu Val Phe Met Glu His Met Ser Asn Met Glu Lys Arg 
        35                  40                  45              


Ile Gln His Ile Leu Asp Met Glu Ala Asn Leu Met Asp Thr Glu His 
    50                  55                  60                  


Phe Gln Asn Phe Ser Met Thr Thr Asp Gln Arg Phe Asn Asp Ile Leu 
65                  70                  75                  80  


Leu Gln Leu Ser Thr Leu Phe Ser Ser Val Gln Gly His Gly Asn Ala 
                85                  90                  95      


Ile Asp Glu Ile Ser Lys Ser Leu Ile Ser Leu Asn Thr Thr Leu Leu 
            100                 105                 110         


Asp Leu Gln Leu Asn Ile Glu Asn Leu Asn Gly Lys Ile Gln Glu Asn 
        115                 120                 125             


Thr Phe Lys Gln Gln Glu Glu Ile Ser Lys Leu Glu Glu Arg Val Tyr 
    130                 135                 140                 


Asn Val Ser Ala Glu Ile Met Ala Met Lys Glu Glu Gln Val His Leu 
145                 150                 155                 160 


Glu Gln Glu Ile Lys Gly Glu Val Lys Val Leu Asn Asn Ile Thr Asn 
                165                 170                 175     


Asp Leu Arg Leu Lys Asp Trp Glu His Ser Gln Thr Leu Arg Asn Ile 
            180                 185                 190         


Thr Leu Ile Gln Gly Pro Pro Gly Pro Pro Gly Glu Lys Gly Asp Arg 
        195                 200                 205             


Gly Pro Thr Gly Glu Ser Gly Pro Arg Gly Phe Pro Gly Pro Ile Gly 
    210                 215                 220                 


Pro Pro Gly Leu Lys Gly Asp Arg Gly Ala Ile Gly Phe Pro Gly Ser 
225                 230                 235                 240 


Arg Gly Leu Pro Gly Tyr Ala Gly Arg Pro Gly Asn Ser Gly Pro Lys 
                245                 250                 255     


Gly Gln Lys Gly Glu Lys Gly Ser Gly Asn Thr Leu Thr Pro Phe Thr 
            260                 265                 270         


Lys Val Arg Leu Val Gly Gly Ser Gly Pro His Glu Gly Arg Val Glu 
        275                 280                 285             


Ile Leu His Ser Gly Gln Trp Gly Thr Ile Cys Asp Asp Arg Trp Glu 
    290                 295                 300                 


Val Arg Val Gly Gln Val Val Cys Arg Ser Leu Gly Tyr Pro Gly Val 
305                 310                 315                 320 


Gln Ala Val His Lys Ala Ala His Phe Gly Gln Gly Thr Gly Pro Ile 
                325                 330                 335     


Trp Leu Asn Glu Val Phe Cys Phe Gly Arg Glu Ser Ser Ile Glu Glu 
            340                 345                 350         


Cys Lys Ile Arg Gln Trp Gly Thr Arg Ala Cys Ser His Ser Glu Asp 
        355                 360                 365             


Ala Gly Val Thr Cys Thr Leu 
    370                 375 


<210>  964
<211>  693
<212>  PRT
<213>  Homo Sapiens

<400>  964

Gln Arg Ser Pro Leu Asn Asp Phe Gln Val Leu Arg Gly Thr Glu Leu 
1               5                   10                  15      


Gln His Leu Leu His Ala Val Val Pro Gly Pro Trp Gln Glu Asp Val 
            20                  25                  30          


Ala Asp Ala Glu Glu Cys Ala Gly Arg Cys Gly Pro Leu Met Asp Cys 
        35                  40                  45              


Arg Ala Phe His Tyr Asn Val Ser Ser His Gly Cys Gln Leu Leu Pro 
    50                  55                  60                  


Trp Thr Gln His Ser Pro His Thr Arg Leu Arg Arg Ser Gly Arg Cys 
65                  70                  75                  80  


Asp Leu Phe Gln Lys Lys Asp Tyr Val Arg Thr Cys Ile Met Asn Asn 
                85                  90                  95      


Gly Val Gly Tyr Arg Gly Thr Met Ala Thr Thr Val Gly Gly Leu Pro 
            100                 105                 110         


Cys Gln Ala Trp Ser His Lys Phe Pro Asn Asp His Lys Tyr Thr Pro 
        115                 120                 125             


Thr Leu Arg Asn Gly Leu Glu Glu Asn Phe Cys Arg Asn Pro Asp Gly 
    130                 135                 140                 


Asp Pro Gly Gly Pro Trp Cys Tyr Thr Thr Asp Pro Ala Val Arg Phe 
145                 150                 155                 160 


Gln Ser Cys Gly Ile Lys Ser Cys Arg Glu Ala Ala Cys Val Trp Cys 
                165                 170                 175     


Asn Gly Glu Glu Tyr Arg Gly Ala Val Asp Arg Thr Glu Ser Gly Arg 
            180                 185                 190         


Glu Cys Gln Arg Trp Asp Leu Gln His Pro His Gln His Pro Phe Glu 
        195                 200                 205             


Pro Gly Lys Phe Leu Asp Gln Gly Leu Asp Asp Asn Tyr Cys Arg Asn 
    210                 215                 220                 


Pro Asp Gly Ser Glu Arg Pro Trp Cys Tyr Thr Thr Asp Pro Gln Ile 
225                 230                 235                 240 


Glu Arg Glu Phe Cys Asp Leu Pro Arg Cys Gly Ser Glu Ala Gln Pro 
                245                 250                 255     


Arg Gln Glu Ala Thr Thr Val Ser Cys Phe Arg Gly Lys Gly Glu Gly 
            260                 265                 270         


Tyr Arg Gly Thr Ala Asn Thr Thr Thr Ala Gly Val Pro Cys Gln Arg 
        275                 280                 285             


Trp Asp Ala Gln Ile Pro His Gln His Arg Phe Thr Pro Glu Lys Tyr 
    290                 295                 300                 


Ala Cys Lys Asp Leu Arg Glu Asn Phe Cys Arg Asn Pro Asp Gly Ser 
305                 310                 315                 320 


Glu Ala Pro Trp Cys Phe Thr Leu Arg Pro Gly Met Arg Ala Ala Phe 
                325                 330                 335     


Cys Tyr Gln Ile Arg Arg Cys Thr Asp Asp Val Arg Pro Gln Asp Cys 
            340                 345                 350         


Tyr His Gly Ala Gly Glu Gln Tyr Arg Gly Thr Val Ser Lys Thr Arg 
        355                 360                 365             


Lys Gly Val Gln Cys Gln Arg Trp Ser Ala Glu Thr Pro His Lys Pro 
    370                 375                 380                 


Gln Phe Thr Phe Thr Ser Glu Pro His Ala Gln Leu Glu Glu Asn Phe 
385                 390                 395                 400 


Cys Arg Asn Pro Asp Gly Asp Ser His Gly Pro Trp Cys Tyr Thr Met 
                405                 410                 415     


Asp Pro Arg Thr Pro Phe Asp Tyr Cys Ala Leu Arg Arg Cys Ala Asp 
            420                 425                 430         


Asp Gln Pro Pro Ser Ile Leu Asp Pro Pro Asp Gln Val Gln Phe Glu 
        435                 440                 445             


Lys Cys Gly Lys Arg Val Asp Arg Leu Asp Gln Arg Arg Ser Lys Leu 
    450                 455                 460                 


Arg Val Val Gly Gly His Pro Gly Asn Ser Pro Trp Thr Val Ser Leu 
465                 470                 475                 480 


Arg Asn Arg Gln Gly Gln His Phe Cys Gly Gly Ser Leu Val Lys Glu 
                485                 490                 495     


Gln Trp Ile Leu Thr Ala Arg Gln Cys Phe Ser Ser Cys His Met Pro 
            500                 505                 510         


Leu Thr Gly Tyr Glu Val Trp Leu Gly Thr Leu Phe Gln Asn Pro Gln 
        515                 520                 525             


His Gly Glu Pro Ser Leu Gln Arg Val Pro Val Ala Lys Met Val Cys 
    530                 535                 540                 


Gly Pro Ser Gly Ser Gln Leu Val Leu Leu Lys Leu Glu Arg Ser Val 
545                 550                 555                 560 


Thr Leu Asn Gln Arg Val Ala Leu Ile Cys Leu Pro Pro Glu Trp Tyr 
                565                 570                 575     


Val Val Pro Pro Gly Thr Lys Cys Glu Ile Ala Gly Trp Gly Glu Thr 
            580                 585                 590         


Lys Gly Thr Gly Asn Asp Thr Val Leu Asn Val Ala Leu Leu Asn Val 
        595                 600                 605             


Ile Ser Asn Gln Glu Cys Asn Ile Lys His Arg Gly Arg Val Arg Glu 
    610                 615                 620                 


Ser Glu Met Cys Thr Glu Gly Leu Leu Ala Pro Val Gly Ala Cys Glu 
625                 630                 635                 640 


Gly Asp Tyr Gly Gly Pro Leu Ala Cys Phe Thr His Asn Cys Trp Val 
                645                 650                 655     


Leu Glu Gly Ile Ile Ile Pro Asn Arg Val Cys Ala Arg Ser Arg Trp 
            660                 665                 670         


Pro Ala Val Phe Thr Arg Val Ser Val Phe Val Asp Trp Ile His Lys 
        675                 680                 685             


Val Met Arg Leu Gly 
    690             


<210>  965
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  965

Pro Lys Pro Ala Thr Val Val Thr Gly Ser Gly His Ala Ser Ser Thr 
1               5                   10                  15      


Pro Gly Gly Glu Lys Glu Thr Ser Ala Thr Gln Arg Ser Ser Val Pro 
            20                  25                  30          


Ser Ser Thr Glu Lys Asn Ala Phe Asn Ser Ser Leu Glu Asp Pro Ser 
        35                  40                  45              


Thr Asp Tyr Tyr Gln Glu Leu Gln Arg Asp Ile Ser Glu Met Phe Leu 
    50                  55                  60                  


Gln Ile Tyr Lys Gln Gly Gly Phe Leu Gly Leu Ser Asn Ile Lys Phe 
65                  70                  75                  80  


Arg Pro Gly Ser Val Val Val Gln Leu Thr Leu Ala Phe Arg Glu Gly 
                85                  90                  95      


Thr Ile Asn Val His Asp Val Glu Thr Gln Phe Asn Gln Tyr Lys Thr 
            100                 105                 110         


Glu Ala Ala Ser Arg Tyr Asn Leu Thr Ile Ser Asp Val Ser Val Ser 
        115                 120                 125             


Asp Val Pro Phe Pro Phe Ser Ala Gln Ser Gly Ala Gly Val Pro Gly 
    130                 135                 140                 


<210>  966
<211>  403
<212>  PRT
<213>  Homo Sapiens

<400>  966

Thr Asn Gln Gly Asn Ser Ala Asp Ala Val Thr Thr Thr Glu Thr Ala 
1               5                   10                  15      


Thr Ser Gly Pro Thr Val Ala Ala Ala Asp Thr Thr Glu Thr Asn Phe 
            20                  25                  30          


Pro Glu Thr Ala Ser Thr Thr Ala Asn Thr Pro Ser Phe Pro Thr Ala 
        35                  40                  45              


Thr Ser Pro Ala Pro Pro Ile Ile Ser Thr His Ser Ser Ser Thr Ile 
    50                  55                  60                  


Pro Thr Pro Ala Pro Pro Ile Ile Ser Thr His Ser Ser Ser Thr Ile 
65                  70                  75                  80  


Pro Ile Pro Thr Ala Ala Asp Ser Glu Ser Thr Thr Asn Val Asn Ser 
                85                  90                  95      


Leu Ala Thr Ser Asp Ile Ile Thr Ala Ser Ser Pro Asn Asp Gly Leu 
            100                 105                 110         


Ile Thr Met Val Pro Ser Glu Thr Gln Ser Asn Asn Glu Met Ser Pro 
        115                 120                 125             


Thr Thr Glu Asp Asn Gln Ser Ser Gly Pro Pro Thr Gly Thr Ala Leu 
    130                 135                 140                 


Leu Glu Thr Ser Thr Leu Asn Ser Thr Gly Pro Ser Asn Pro Cys Gln 
145                 150                 155                 160 


Asp Asp Pro Cys Ala Asp Asn Ser Leu Cys Val Lys Leu His Asn Thr 
                165                 170                 175     


Ser Phe Cys Leu Cys Leu Glu Gly Tyr Tyr Tyr Asn Ser Ser Thr Cys 
            180                 185                 190         


Lys Lys Gly Lys Val Phe Pro Gly Lys Ile Ser Val Thr Val Ser Glu 
        195                 200                 205             


Thr Phe Asp Pro Glu Glu Lys His Ser Met Ala Tyr Gln Asp Leu His 
    210                 215                 220                 


Ser Glu Ile Thr Ser Leu Phe Lys Asp Val Phe Gly Thr Ser Val Tyr 
225                 230                 235                 240 


Gly Gln Thr Val Ile Leu Thr Val Ser Thr Ser Leu Ser Pro Arg Ser 
                245                 250                 255     


Glu Met Arg Ala Asp Asp Lys Phe Val Asn Val Thr Ile Val Thr Ile 
            260                 265                 270         


Leu Ala Glu Thr Thr Ser Asp Asn Glu Lys Thr Val Thr Glu Lys Ile 
        275                 280                 285             


Asn Lys Ala Ile Arg Ser Ser Ser Ser Asn Phe Leu Asn Tyr Asp Leu 
    290                 295                 300                 


Thr Leu Arg Cys Asp Tyr Tyr Gly Cys Asn Gln Thr Ala Asp Asp Cys 
305                 310                 315                 320 


Leu Asn Gly Leu Ala Cys Asp Cys Lys Ser Asp Leu Gln Arg Pro Asn 
                325                 330                 335     


Pro Gln Ser Pro Phe Cys Val Ala Ser Ser Leu Lys Cys Pro Asp Ala 
            340                 345                 350         


Cys Asn Ala Gln His Lys Gln Cys Leu Ile Lys Lys Ser Gly Gly Ala 
        355                 360                 365             


Pro Glu Cys Ala Cys Val Pro Gly Tyr Gln Glu Asp Ala Asn Gly Asn 
    370                 375                 380                 


Cys Gln Lys Cys Ala Phe Gly Tyr Ser Gly Leu Asp Cys Lys Asp Lys 
385                 390                 395                 400 


Phe Gln Leu 
            


<210>  967
<211>  731
<212>  PRT
<213>  Homo Sapiens

<400>  967

Ser Thr Pro Val Ile Thr Ser Thr Gln Val Ser Ser Ser Pro Val Thr 
1               5                   10                  15      


Pro Glu Gly Thr Thr Met Pro Ile Trp Thr Pro Ser Glu Gly Ser Thr 
            20                  25                  30          


Pro Leu Thr Thr Met Pro Val Ser Thr Thr Arg Val Thr Ser Ser Glu 
        35                  40                  45              


Gly Ser Thr Leu Ser Thr Pro Ser Val Val Thr Ser Thr Pro Val Thr 
    50                  55                  60                  


Thr Ser Thr Glu Ala Ile Ser Ser Ser Ala Thr Leu Asp Ser Thr Thr 
65                  70                  75                  80  


Met Ser Val Ser Met Pro Met Glu Ile Ser Thr Leu Gly Thr Thr Ile 
                85                  90                  95      


Leu Val Ser Thr Thr Pro Val Thr Arg Phe Pro Glu Ser Ser Thr Pro 
            100                 105                 110         


Ser Ile Pro Ser Val Tyr Thr Ser Met Ser Met Thr Thr Ala Ser Glu 
        115                 120                 125             


Gly Ser Ser Ser Pro Thr Thr Leu Glu Gly Thr Thr Thr Met Pro Met 
    130                 135                 140                 


Ser Thr Thr Ser Glu Arg Ser Thr Leu Leu Thr Thr Val Leu Ile Ser 
145                 150                 155                 160 


Pro Ile Ser Val Met Ser Pro Ser Glu Ala Ser Thr Leu Ser Thr Pro 
                165                 170                 175     


Pro Gly Asp Thr Ser Thr Pro Leu Leu Thr Ser Thr Lys Ala Gly Ser 
            180                 185                 190         


Phe Ser Ile Pro Ala Glu Val Thr Thr Ile Arg Ile Ser Ile Thr Ser 
        195                 200                 205             


Glu Arg Ser Thr Pro Leu Thr Thr Leu Leu Val Ser Thr Thr Leu Pro 
    210                 215                 220                 


Thr Ser Phe Pro Gly Ala Ser Ile Ala Ser Thr Pro Pro Leu Asp Thr 
225                 230                 235                 240 


Ser Thr Thr Phe Thr Pro Ser Thr Asp Thr Ala Ser Thr Pro Thr Ile 
                245                 250                 255     


Pro Val Ala Thr Thr Ile Ser Val Ser Val Ile Thr Glu Gly Ser Thr 
            260                 265                 270         


Pro Gly Thr Thr Ile Phe Ile Pro Ser Thr Pro Val Thr Ser Ser Thr 
        275                 280                 285             


Ala Asp Val Phe Pro Ala Thr Thr Gly Ala Val Ser Thr Pro Val Ile 
    290                 295                 300                 


Thr Ser Thr Glu Leu Asn Thr Pro Ser Thr Ser Ser Ser Ser Thr Thr 
305                 310                 315                 320 


Thr Ser Phe Ser Thr Thr Lys Glu Phe Thr Thr Pro Ala Met Thr Thr 
                325                 330                 335     


Ala Ala Pro Leu Thr Tyr Val Thr Met Ser Thr Ala Pro Ser Thr Pro 
            340                 345                 350         


Arg Thr Thr Ser Arg Gly Cys Thr Thr Ser Ala Ser Thr Leu Ser Ala 
        355                 360                 365             


Thr Ser Thr Pro His Thr Ser Thr Ser Val Thr Thr Arg Pro Val Thr 
    370                 375                 380                 


Pro Ser Ser Glu Ser Ser Arg Pro Ser Thr Ile Thr Ser His Thr Ile 
385                 390                 395                 400 


Pro Pro Thr Phe Pro Pro Ala His Ser Ser Thr Pro Pro Thr Thr Ser 
                405                 410                 415     


Ala Ser Ser Thr Thr Val Asn Pro Glu Ala Val Thr Thr Met Thr Thr 
            420                 425                 430         


Arg Thr Lys Pro Ser Thr Arg Thr Thr Ser Phe Pro Thr Val Thr Thr 
        435                 440                 445             


Thr Ala Val Pro Thr Asn Thr Thr Ile Lys Ser Asn Pro Thr Ser Thr 
    450                 455                 460                 


Pro Thr Val Pro Arg Thr Thr Thr Cys Phe Gly Asp Gly Cys Gln Asn 
465                 470                 475                 480 


Thr Ala Ser Arg Cys Lys Asn Gly Gly Thr Trp Asp Gly Leu Lys Cys 
                485                 490                 495     


Gln Cys Pro Asn Leu Tyr Tyr Gly Glu Leu Cys Glu Glu Val Val Ser 
            500                 505                 510         


Ser Ile Asp Ile Gly Pro Pro Glu Thr Ile Ser Ala Gln Met Glu Leu 
        515                 520                 525             


Thr Val Thr Val Thr Ser Val Lys Phe Thr Glu Glu Leu Lys Asn His 
    530                 535                 540                 


Ser Ser Gln Glu Phe Gln Glu Phe Lys Gln Thr Phe Thr Glu Gln Met 
545                 550                 555                 560 


Asn Ile Val Tyr Ser Gly Ile Pro Glu Tyr Val Gly Val Asn Ile Thr 
                565                 570                 575     


Lys Leu Arg Leu Gly Ser Val Val Val Glu His Asp Val Leu Leu Arg 
            580                 585                 590         


Thr Lys Tyr Thr Pro Glu Tyr Lys Thr Val Leu Asp Asn Ala Thr Glu 
        595                 600                 605             


Val Val Lys Glu Lys Ile Thr Lys Val Thr Thr Gln Gln Ile Met Ile 
    610                 615                 620                 


Asn Asp Ile Cys Ser Asp Met Met Cys Phe Asn Thr Thr Gly Thr Gln 
625                 630                 635                 640 


Val Gln Asn Ile Thr Val Thr Gln Tyr Asp Pro Glu Glu Asp Cys Arg 
                645                 650                 655     


Lys Met Ala Lys Glu Tyr Gly Asp Tyr Phe Val Val Glu Tyr Arg Asp 
            660                 665                 670         


Gln Lys Pro Tyr Cys Ile Ser Pro Cys Glu Pro Gly Phe Ser Val Ser 
        675                 680                 685             


Lys Asn Cys Asn Leu Gly Lys Cys Gln Met Ser Leu Ser Gly Pro Gln 
    690                 695                 700                 


Cys Leu Cys Val Thr Thr Glu Thr His Trp Tyr Ser Gly Glu Thr Cys 
705                 710                 715                 720 


Asn Gln Gly Thr Gln Lys Ser Leu Val Tyr Gly 
                725                 730     


<210>  968
<211>  530
<212>  PRT
<213>  Homo Sapiens

<400>  968

Gly Pro Ser Thr Arg Arg Ala Asp Thr Ala Met Thr Thr Asp Asp Thr 
1               5                   10                  15      


Glu Val Pro Ala Met Thr Leu Ala Pro Gly His Ala Ala Leu Glu Thr 
            20                  25                  30          


Gln Thr Leu Ser Ala Glu Thr Ser Ser Arg Ala Ser Thr Pro Ala Gly 
        35                  40                  45              


Pro Val Pro Glu Ala Glu Thr Arg Gly Ala Lys Arg Ile Ser Pro Ala 
    50                  55                  60                  


Arg Glu Thr Arg Ser Phe Thr Lys Thr Ser Pro Asn Phe Met Val Leu 
65                  70                  75                  80  


Ile Ala Thr Ser Val Glu Thr Ser Ala Ala Ser Gly Ser Pro Glu Gly 
                85                  90                  95      


Ala Gly Met Thr Thr Val Gln Thr Ile Thr Gly Ser Asp Pro Glu Glu 
            100                 105                 110         


Ala Ile Phe Asp Thr Leu Cys Thr Asp Asp Ser Ser Glu Glu Ala Lys 
        115                 120                 125             


Thr Leu Thr Met Asp Ile Leu Thr Leu Ala His Thr Ser Thr Glu Ala 
    130                 135                 140                 


Lys Gly Leu Ser Ser Glu Ser Ser Ala Ser Ser Asp Gly Pro His Pro 
145                 150                 155                 160 


Val Ile Thr Pro Ser Arg Ala Ser Glu Ser Ser Ala Ser Ser Asp Gly 
                165                 170                 175     


Pro His Pro Val Ile Thr Pro Ser Arg Ala Ser Glu Ser Ser Ala Ser 
            180                 185                 190         


Ser Asp Gly Pro His Pro Val Ile Thr Pro Ser Arg Ala Ser Glu Ser 
        195                 200                 205             


Ser Ala Ser Ser Asp Gly Pro His Pro Val Ile Thr Pro Ser Trp Ser 
    210                 215                 220                 


Pro Gly Ser Asp Val Thr Leu Leu Ala Glu Ala Leu Val Thr Val Thr 
225                 230                 235                 240 


Asn Ile Glu Val Ile Asn Cys Ser Ile Thr Glu Ile Glu Thr Thr Thr 
                245                 250                 255     


Ser Ser Ile Pro Gly Ala Ser Asp Thr Asp Pro Ile Pro Thr Glu Gly 
            260                 265                 270         


Val Lys Ala Ser Ser Thr Ser Asp Pro Pro Ala Leu Pro Asp Ser Thr 
        275                 280                 285             


Glu Ala Lys Pro His Ile Thr Glu Val Thr Ala Ser Ala Glu Thr Leu 
    290                 295                 300                 


Ser Thr Ala Gly Thr Thr Glu Ser Ala Ala Pro Asp Ala Thr Ile Gly 
305                 310                 315                 320 


Thr Pro Leu Pro Thr Asn Ser Thr Ile Glu Arg Glu Val Thr Ala Pro 
                325                 330                 335     


Gly Ala Thr Thr Leu Ser Gly Ala Leu Ala Thr Gly Asn Pro Leu Glu 
            340                 345                 350         


Glu Thr Ser Ala Leu Ser Val Glu Thr Pro Ser Tyr Val Lys Val Ser 
        355                 360                 365             


Gly Ala Ala Pro Val Ser Ile Glu Ala Gly Ser Ala Val Gly Lys Thr 
    370                 375                 380                 


Thr Ser Phe Ala Gly Ser Ser Ala Ser Ser Tyr Ser Pro Ser Glu Ala 
385                 390                 395                 400 


Ala Leu Lys Asn Phe Thr Pro Ser Glu Thr Leu Thr Thr Asp Ile Ala 
                405                 410                 415     


Thr Lys Gly Pro Phe Pro Thr Ser Arg Asp Pro Leu Pro Ser Val Pro 
            420                 425                 430         


Pro Thr Thr Thr Asn Ser Ser Arg Gly Thr Asn Ser Thr Leu Ala Lys 
        435                 440                 445             


Ile Thr Thr Ser Ala Lys Thr Thr Met Lys Pro Pro Thr Ala Thr Pro 
    450                 455                 460                 


Thr Thr Ala Arg Thr Arg Pro Thr Thr Asp Met Ser Ala Gly Glu Asn 
465                 470                 475                 480 


Gly Gly Phe Leu Leu Leu Arg Leu Ser Val Ala Ser Pro Glu Asp Leu 
                485                 490                 495     


Thr Asp Pro Arg Val Ala Glu Arg Leu Met Gln Gln Leu His Arg Glu 
            500                 505                 510         


Leu His Ala His Ala Pro His Phe Gln Val Ser Leu Leu Arg Val Arg 
        515                 520                 525             


Arg Gly 
    530 


<210>  969
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  969

Asn Glu Thr Ser Thr Ser Ala Asn Thr Gly Ser Ser Val Ile Ser Ser 
1               5                   10                  15      


Gly Ala Ser Thr Ala Thr Asn Ser Gly Ser Ser Val Thr Ser Ser Gly 
            20                  25                  30          


Val Ser Thr Ala Thr Ile Ser Gly Ser Ser Val Thr Ser Asn Gly Val 
        35                  40                  45              


Ser Ile Val Thr Asn Ser Glu Phe His Thr Thr Ser Ser Gly Ile Ser 
    50                  55                  60                  


Thr Ala Thr Asn Ser Glu Phe Ser Thr Ala Ser Ser Gly Ile Ser Ile 
65                  70                  75                  80  


Ala Thr Asn Ser Glu Ser Ser Thr Thr Ser Ser Gly Ala Ser Thr Ala 
                85                  90                  95      


Thr Asn Ser Glu Ser Ser Thr Pro Ser Ser Gly Ala Ser Thr Ala Thr 
            100                 105                 110         


Asn Ser Asp Ser Ser Thr Thr Ser Ser Gly Ala Ser Thr Ala Thr Asn 
        115                 120                 125             


Ser Asp Ser Ser Thr Thr Ser Ser Glu Ala Ser Thr Ala Thr Asn Ser 
    130                 135                 140                 


Glu Ser Ser Thr Thr Ser Ser Gly Ala Ser Thr Ala Thr Asn Ser Glu 
145                 150                 155                 160 


Ser Ser Thr Thr Ser Ser Gly Ala Ser Thr Ala Thr Asn Ser Glu Ser 
                165                 170                 175     


Ser Thr Thr Ser Ser Gly Ala Ser Thr Ala Thr Asn Ser Gly Ser Ser 
            180                 185                 190         


Thr Thr Ser Ser Gly Thr Ser Thr Ala Thr Asn Ser Glu Ser Ser Thr 
        195                 200                 205             


Val Ser Ser Gly Ala Ser Thr Ala Thr Thr Ser Glu Ser Ser Thr Thr 
    210                 215                 220                 


Ser Ser Gly Ala Ser Thr Ala Thr Asn Ser Glu Ser Ser Thr Val Ser 
225                 230                 235                 240 


Ser Gly Ala Ser Thr Ala Thr Asn Ser Glu Ser Ser Thr Thr Ser Ser 
                245                 250                 255     


Gly Ala Asn Thr Ala Thr Asn Ser Gly Ser Ser Val Thr Ser Ala Gly 
            260                 265                 270         


Ser Gly Thr Ala Ala Leu Thr Gly Met His Thr Thr Ser His Ser Ala 
        275                 280                 285             


Ser Thr Ala Val Ser Glu Ala Lys Pro Gly Gly Ser Leu Val Pro Trp 
    290                 295                 300                 


Glu 
305 


<210>  970
<211>  379
<212>  PRT
<213>  Homo Sapiens

<400>  970

Pro Arg Cys Leu Gly Pro His Gly Glu Pro Val Lys Val Gly His Thr 
1               5                   10                  15      


Val Gly Met Asp Cys Gln Glu Cys Thr Cys Glu Ala Ala Thr Trp Thr 
            20                  25                  30          


Leu Thr Cys Arg Pro Lys Leu Cys Pro Leu Pro Pro Ala Cys Pro Leu 
        35                  40                  45              


Pro Gly Phe Val Pro Val Pro Ala Ala Pro Gln Ala Gly Gln Cys Cys 
    50                  55                  60                  


Pro Gln Tyr Ser Cys Ala Cys Asn Thr Ser Arg Cys Pro Ala Pro Val 
65                  70                  75                  80  


Gly Cys Pro Glu Gly Ala Arg Ala Ile Pro Thr Tyr Gln Glu Gly Ala 
                85                  90                  95      


Cys Cys Pro Val Gln Asn Cys Ser Trp Thr Val Cys Ser Ile Asn Gly 
            100                 105                 110         


Thr Leu Tyr Gln Pro Gly Ala Val Val Ser Ser Ser Leu Cys Glu Thr 
        115                 120                 125             


Cys Arg Cys Glu Leu Pro Gly Gly Pro Pro Ser Asp Ala Phe Val Val 
    130                 135                 140                 


Ser Cys Glu Thr Gln Ile Cys Asn Thr His Cys Pro Val Gly Phe Glu 
145                 150                 155                 160 


Tyr Gln Glu Gln Ser Gly Gln Cys Cys Gly Thr Cys Val Gln Val Ala 
                165                 170                 175     


Cys Val Thr Asn Thr Ser Lys Ser Pro Ala His Leu Phe Tyr Pro Gly 
            180                 185                 190         


Glu Thr Trp Ser Asp Ala Gly Asn His Cys Val Thr His Gln Cys Glu 
        195                 200                 205             


Lys His Gln Asp Gly Leu Val Val Val Thr Thr Lys Lys Ala Cys Pro 
    210                 215                 220                 


Pro Leu Ser Cys Ser Leu Asp Glu Ala Arg Met Ser Lys Asp Gly Cys 
225                 230                 235                 240 


Cys Arg Phe Cys Pro Pro Pro Pro Pro Pro Tyr Gln Asn Gln Ser Thr 
                245                 250                 255     


Cys Ala Val Tyr His Arg Ser Leu Ile Ile Gln Gln Gln Gly Cys Ser 
            260                 265                 270         


Ser Ser Glu Pro Val Arg Leu Ala Tyr Cys Arg Gly Asn Cys Gly Asp 
        275                 280                 285             


Ser Ser Ser Met Tyr Ser Leu Glu Gly Asn Thr Val Glu His Arg Cys 
    290                 295                 300                 


Gln Cys Cys Gln Glu Leu Arg Thr Ser Leu Arg Asn Val Thr Leu His 
305                 310                 315                 320 


Cys Thr Asp Gly Ser Ser Arg Ala Phe Ser Tyr Thr Glu Val Glu Glu 
                325                 330                 335     


Cys Gly Cys Met Gly Arg Arg Cys Pro Ala Pro Gly Asp Thr Gln His 
            340                 345                 350         


Ser Glu Glu Ala Glu Pro Glu Pro Ser Gln Glu Ala Glu Ser Gly Ser 
        355                 360                 365             


Trp Glu Arg Gly Val Pro Val Ser Pro Met His 
    370                 375                 


<210>  971
<211>  386
<212>  PRT
<213>  Homo Sapiens

<400>  971

Leu Pro Lys Ala Pro Val Ile Thr Thr Pro Leu Glu Thr Val Asp Ala 
1               5                   10                  15      


Leu Val Glu Glu Val Ala Thr Phe Met Cys Ala Val Glu Ser Tyr Pro 
            20                  25                  30          


Gln Pro Glu Ile Ser Trp Thr Arg Asn Lys Ile Leu Ile Lys Leu Phe 
        35                  40                  45              


Asp Thr Arg Tyr Ser Ile Arg Glu Asn Gly Gln Leu Leu Thr Ile Leu 
    50                  55                  60                  


Ser Val Glu Asp Ser Asp Asp Gly Ile Tyr Cys Cys Thr Ala Asn Asn 
65                  70                  75                  80  


Gly Val Gly Gly Ala Val Glu Ser Cys Gly Ala Leu Gln Val Lys Met 
                85                  90                  95      


Lys Pro Lys Ile Thr Arg Pro Pro Ile Asn Val Lys Ile Ile Glu Gly 
            100                 105                 110         


Leu Lys Ala Val Leu Pro Cys Thr Thr Met Gly Asn Pro Lys Pro Ser 
        115                 120                 125             


Val Ser Trp Ile Lys Gly Asp Ser Pro Leu Arg Glu Asn Ser Arg Ile 
    130                 135                 140                 


Ala Val Leu Glu Ser Gly Ser Leu Arg Ile His Asn Val Gln Lys Glu 
145                 150                 155                 160 


Asp Ala Gly Gln Tyr Arg Cys Val Ala Lys Asn Ser Leu Gly Thr Ala 
                165                 170                 175     


Tyr Ser Lys Val Val Lys Leu Glu Val Glu Glu Glu Ser Glu Pro Glu 
            180                 185                 190         


Gln Asp Thr Lys Val Phe Ala Arg Ile Leu Arg Ala Pro Glu Ser His 
        195                 200                 205             


Asn Val Thr Phe Gly Ser Phe Val Thr Leu His Cys Thr Ala Thr Gly 
    210                 215                 220                 


Ile Pro Val Pro Thr Ile Thr Trp Ile Glu Asn Gly Asn Ala Val Ser 
225                 230                 235                 240 


Ser Gly Ser Ile Gln Glu Ser Val Lys Asp Arg Val Ile Asp Ser Arg 
                245                 250                 255     


Leu Gln Leu Phe Ile Thr Lys Pro Gly Leu Tyr Thr Cys Ile Ala Thr 
            260                 265                 270         


Asn Lys His Gly Glu Lys Phe Ser Thr Ala Lys Ala Ala Ala Thr Ile 
        275                 280                 285             


Ser Ile Ala Glu Trp Arg Glu Tyr Cys Leu Ala Val Lys Glu Leu Phe 
    290                 295                 300                 


Cys Ala Lys Glu Trp Leu Val Met Glu Glu Lys Thr His Arg Gly Leu 
305                 310                 315                 320 


Tyr Arg Ser Glu Met His Leu Leu Ser Val Pro Glu Cys Ser Lys Leu 
                325                 330                 335     


Pro Ser Met His Trp Asp Pro Thr Ala Cys Ala Arg Leu Pro His Leu 
            340                 345                 350         


Ala Phe Pro Pro Met Thr Ser Ser Lys Pro Ser Val Asp Ile Pro Asn 
        355                 360                 365             


Leu Pro Ser Ser Ser Ser Ser Ser Phe Ser Val Ser Pro Thr Tyr Ser 
    370                 375                 380                 


Met Thr 
385     


<210>  972
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  972

Val Leu Leu His Ser Gly Ser Ser Val Pro Ala Ala Ala Gly Ser Ser 
1               5                   10                  15      


Val Val Ser Glu Ser Ala Val Ser Trp Glu Ala Gly Ala Arg Ala Val 
            20                  25                  30          


Leu Arg Cys Gln Ser Pro Arg Met Val Trp Thr Gln Asp Arg Leu His 
        35                  40                  45              


Asp Arg Gln Arg Val Leu His Trp Asp Leu Arg Gly Pro Gly Gly Gly 
    50                  55                  60                  


Pro Ala Arg Arg Leu Leu Asp Leu Tyr Ser Ala Gly Glu Gln Arg Val 
65                  70                  75                  80  


Tyr Glu Ala Arg Asp Arg Gly Arg Leu Glu Leu Ser Ala Ser Ala Phe 
                85                  90                  95      


Asp Asp Gly Asn Phe Ser Leu Leu Ile Arg Ala Val Glu Glu Thr Asp 
            100                 105                 110         


Ala Gly Leu Tyr Thr Cys Asn Leu His His His Tyr Cys His Leu Tyr 
        115                 120                 125             


Glu Ser Leu Ala Val Arg Leu Glu Val Thr Asp Gly Pro Pro Ala Thr 
    130                 135                 140                 


Pro Ala Tyr Trp Asp Gly Glu Lys Glu Val Leu Ala Val Ala Arg Gly 
145                 150                 155                 160 


Ala Pro Ala Leu Leu Thr Cys Val Asn Arg Gly His Val Trp Thr Asp 
                165                 170                 175     


Arg His Val Glu Glu Ala Gln Gln Val Val His Trp Asp Arg Gln Pro 
            180                 185                 190         


Pro Gly Val Pro His Asp Arg Ala Asp Arg Leu Leu Asp Leu Tyr Ala 
        195                 200                 205             


Ser Gly Glu Arg Arg Ala Tyr Gly Pro Leu Phe Leu Arg Asp Arg Val 
    210                 215                 220                 


Ala Val Gly Ala Asp Ala Phe Glu Arg Gly Asp Phe Ser Leu Arg Ile 
225                 230                 235                 240 


Glu Pro Leu Glu Val Ala Asp Glu Gly Thr Tyr Ser Cys His Leu His 
                245                 250                 255     


His His Tyr Cys Gly Leu His Glu Arg Arg Val Phe His Leu Thr Val 
            260                 265                 270         


Ala Glu Pro His Ala Glu Pro Pro Pro Arg Gly Ser Pro Gly Asn Gly 
        275                 280                 285             


Ser Ser His Ser Gly Ala Pro Gly Pro Asp Pro Thr Leu Ala Arg Gly 
    290                 295                 300                 


His Asn Val Ile Asn Val Ile Val Pro Glu Ser Arg Ala His Phe Phe 
305                 310                 315                 320 


Gln Gln 
        


<210>  973
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  973

Met Ala Thr Ser Thr Gly Arg Trp Leu Leu Leu Arg Leu Ala Leu Phe 
1               5                   10                  15      


Gly Phe Leu Trp Glu Ala Ser Gly Gly Leu Asp Ser Gly Ala Ser Arg 
            20                  25                  30          


Asp Asp Asp Leu Leu Leu Pro Tyr Pro Arg Ala Arg Ala Arg Leu Pro 
        35                  40                  45              


Arg Asp Cys Thr Arg Val Arg Ala Gly Asn Arg Glu His Glu Ser Trp 
    50                  55                  60                  


Pro Pro Pro Pro Ala Thr Pro Gly Ala Gly Gly Leu Ala Val Arg Thr 
65                  70                  75                  80  


Phe Val Ser His Phe Arg Asp Arg Ala Val Ala Gly His Leu Thr Arg 
                85                  90                  95      


Ala Val Glu Pro Leu Arg Thr Phe Ser Val Leu Glu Pro Gly Gly Pro 
            100                 105                 110         


Gly Gly Cys Ala Ala Arg Arg Arg Ala Thr Val Glu Glu Thr Ala Arg 
        115                 120                 125             


Ala Ala Asp Cys Arg Val Ala Gln Asn Gly Gly Phe Phe Arg Met Asn 
    130                 135                 140                 


Ser Gly Glu Cys Leu Gly Asn Val Val Ser Asp Glu Arg Arg Val Ser 
145                 150                 155                 160 


Ser Ser Gly Gly Leu Gln Asn Ala Gln Phe Gly Ile Arg Arg Asp Gly 
                165                 170                 175     


Thr Leu Val Thr Gly Tyr Leu Ser Glu Glu Glu Val Leu Asp Thr Glu 
            180                 185                 190         


Asn Pro Phe Val Gln Leu Leu Ser Gly Val Val Trp Leu Ile Arg Asn 
        195                 200                 205             


Gly Ser Ile Tyr Ile Asn Glu Ser Gln Ala Thr Glu Cys Asp Glu Thr 
    210                 215                 220                 


Gln Glu Thr Gly Ser Phe Ser Lys Phe Val Asn Val Ile Ser Ala Arg 
225                 230                 235                 240 


Thr Ala Ile Gly His Asp Arg Lys Gly Gln Leu Val Leu Phe His Ala 
                245                 250                 255     


Asp Gly Gln Thr Glu Gln Arg Gly Ile Asn Leu Trp Glu Met Ala Glu 
            260                 265                 270         


Phe Leu Leu Lys Gln Asp Val Val Asn Ala Ile Asn Leu Asp Gly Gly 
        275                 280                 285             


Gly Ser Ala Thr Phe Val Leu Asn Gly Thr Leu Ala Ser Tyr Pro Ser 
    290                 295                 300                 


Asp His Trp Gln Ala 
305                 


<210>  974
<211>  699
<212>  PRT
<213>  Homo Sapiens

<400>  974

Leu Gln Val Asp Ile Val Pro Ser Gln Gly Glu Ile Ser Val Gly Glu 
1               5                   10                  15      


Ser Lys Phe Phe Leu Cys Gln Val Ala Gly Asp Ala Lys Asp Lys Asp 
            20                  25                  30          


Ile Ser Trp Phe Ser Pro Asn Gly Glu Lys Leu Thr Pro Asn Gln Gln 
        35                  40                  45              


Arg Ile Ser Val Val Trp Asn Asp Asp Ser Ser Ser Thr Leu Thr Ile 
    50                  55                  60                  


Tyr Asn Ala Asn Ile Asp Asp Ala Gly Ile Tyr Lys Cys Val Val Thr 
65                  70                  75                  80  


Gly Glu Asp Gly Ser Glu Ser Glu Ala Thr Val Asn Val Lys Ile Phe 
                85                  90                  95      


Gln Lys Leu Met Phe Lys Asn Ala Pro Thr Pro Gln Glu Phe Arg Glu 
            100                 105                 110         


Gly Glu Asp Ala Val Ile Val Cys Asp Val Val Ser Ser Leu Pro Pro 
        115                 120                 125             


Thr Ile Ile Trp Lys His Lys Gly Arg Asp Val Ile Leu Lys Lys Asp 
    130                 135                 140                 


Val Arg Phe Ile Val Leu Ser Asn Asn Tyr Leu Gln Ile Arg Gly Ile 
145                 150                 155                 160 


Lys Lys Thr Asp Glu Gly Thr Tyr Arg Cys Glu Gly Arg Ile Leu Ala 
                165                 170                 175     


Arg Gly Glu Ile Asn Phe Lys Asp Ile Gln Val Ile Val Asn Val Pro 
            180                 185                 190         


Pro Thr Ile Gln Ala Arg Gln Asn Ile Val Asn Ala Thr Ala Asn Leu 
        195                 200                 205             


Gly Gln Ser Val Thr Leu Val Cys Asp Ala Glu Gly Phe Pro Glu Pro 
    210                 215                 220                 


Thr Met Ser Trp Thr Lys Asp Gly Glu Gln Ile Glu Gln Glu Glu Asp 
225                 230                 235                 240 


Asp Glu Lys Tyr Ile Phe Ser Asp Asp Ser Ser Gln Leu Thr Ile Lys 
                245                 250                 255     


Lys Val Asp Lys Asn Asp Glu Ala Glu Tyr Ile Cys Ile Ala Glu Asn 
            260                 265                 270         


Lys Ala Gly Glu Gln Asp Ala Thr Ile His Leu Lys Val Phe Ala Lys 
        275                 280                 285             


Pro Lys Ile Thr Tyr Val Glu Asn Gln Thr Ala Met Glu Leu Glu Glu 
    290                 295                 300                 


Gln Val Thr Leu Thr Cys Glu Ala Ser Gly Asp Pro Ile Pro Ser Ile 
305                 310                 315                 320 


Thr Trp Arg Thr Ser Thr Arg Asn Ile Ser Ser Glu Glu Lys Ala Ser 
                325                 330                 335     


Trp Thr Arg Pro Glu Lys Gln Glu Thr Leu Asp Gly His Met Val Val 
            340                 345                 350         


Arg Ser His Ala Arg Val Ser Ser Leu Thr Leu Lys Ser Ile Gln Tyr 
        355                 360                 365             


Thr Asp Ala Gly Glu Tyr Ile Cys Thr Ala Ser Asn Thr Ile Gly Gln 
    370                 375                 380                 


Asp Ser Gln Ser Met Tyr Leu Glu Val Gln Tyr Ala Pro Lys Leu Gln 
385                 390                 395                 400 


Gly Pro Val Ala Val Tyr Thr Trp Glu Gly Asn Gln Val Asn Ile Thr 
                405                 410                 415     


Cys Glu Val Phe Ala Tyr Pro Ser Ala Thr Ile Ser Trp Phe Arg Asp 
            420                 425                 430         


Gly Gln Leu Leu Pro Ser Ser Asn Tyr Ser Asn Ile Lys Ile Tyr Asn 
        435                 440                 445             


Thr Pro Ser Ala Ser Tyr Leu Glu Val Thr Pro Asp Ser Glu Asn Asp 
    450                 455                 460                 


Phe Gly Asn Tyr Asn Cys Thr Ala Val Asn Arg Ile Gly Gln Glu Ser 
465                 470                 475                 480 


Leu Glu Phe Ile Leu Val Gln Ala Asp Thr Pro Ser Ser Pro Ser Ile 
                485                 490                 495     


Asp Gln Val Glu Pro Tyr Ser Ser Thr Ala Gln Val Gln Phe Asp Glu 
            500                 505                 510         


Pro Glu Ala Thr Gly Gly Val Pro Ile Leu Lys Tyr Lys Ala Glu Trp 
        515                 520                 525             


Arg Ala Val Gly Glu Glu Val Trp His Ser Lys Trp Tyr Asp Ala Lys 
    530                 535                 540                 


Glu Ala Ser Met Glu Gly Ile Val Thr Ile Val Gly Leu Lys Pro Glu 
545                 550                 555                 560 


Thr Thr Tyr Ala Val Arg Leu Ala Ala Leu Asn Gly Lys Gly Leu Gly 
                565                 570                 575     


Glu Ile Ser Ala Ala Ser Glu Phe Lys Thr Gln Pro Val Gln Gly Glu 
            580                 585                 590         


Pro Ser Ala Pro Lys Leu Glu Gly Gln Met Gly Glu Asp Gly Asn Ser 
        595                 600                 605             


Ile Lys Val Asn Leu Ile Lys Gln Asp Asp Gly Gly Ser Pro Ile Arg 
    610                 615                 620                 


His Tyr Leu Val Arg Tyr Arg Ala Leu Ser Ser Glu Trp Lys Pro Glu 
625                 630                 635                 640 


Ile Arg Leu Pro Ser Gly Ser Asp His Val Met Leu Lys Ser Leu Asp 
                645                 650                 655     


Trp Asn Ala Glu Tyr Glu Val Tyr Val Val Ala Glu Asn Gln Gln Gly 
            660                 665                 670         


Lys Ser Lys Ala Ala His Phe Val Phe Arg Thr Ser Ala Gln Pro Thr 
        675                 680                 685             


Ala Ile Pro Ala Asn Gly Ser Pro Thr Ser Gly 
    690                 695                 


<210>  975
<211>  678
<212>  PRT
<213>  Homo Sapiens

<400>  975

Leu Leu Gln Val Thr Ile Ser Leu Ser Lys Val Glu Leu Ser Val Gly 
1               5                   10                  15      


Glu Ser Lys Phe Phe Thr Cys Thr Ala Ile Gly Glu Pro Glu Ser Ile 
            20                  25                  30          


Asp Trp Tyr Asn Pro Gln Gly Glu Lys Ile Ile Ser Thr Gln Arg Val 
        35                  40                  45              


Val Val Gln Lys Glu Gly Val Arg Ser Arg Leu Thr Ile Tyr Asn Ala 
    50                  55                  60                  


Asn Ile Glu Asp Ala Gly Ile Tyr Arg Cys Gln Ala Thr Asp Ala Lys 
65                  70                  75                  80  


Gly Gln Thr Gln Glu Ala Thr Val Val Leu Glu Ile Tyr Gln Lys Leu 
                85                  90                  95      


Thr Phe Arg Glu Val Val Ser Pro Gln Glu Phe Lys Gln Gly Glu Asp 
            100                 105                 110         


Ala Glu Val Val Cys Arg Val Ser Ser Ser Pro Ala Pro Ala Val Ser 
        115                 120                 125             


Trp Leu Tyr His Asn Glu Glu Val Thr Thr Ile Ser Asp Asn Arg Phe 
    130                 135                 140                 


Ala Met Leu Ala Asn Asn Asn Leu Gln Ile Leu Asn Ile Asn Lys Ser 
145                 150                 155                 160 


Asp Glu Gly Ile Tyr Arg Cys Glu Gly Arg Val Glu Ala Arg Gly Glu 
                165                 170                 175     


Ile Asp Phe Arg Asp Ile Ile Val Ile Val Asn Val Pro Pro Ala Ile 
            180                 185                 190         


Ser Met Pro Gln Lys Ser Phe Asn Ala Thr Ala Glu Arg Gly Glu Glu 
        195                 200                 205             


Met Thr Phe Ser Cys Arg Ala Ser Gly Ser Pro Glu Pro Ala Ile Ser 
    210                 215                 220                 


Trp Phe Arg Asn Gly Lys Leu Ile Glu Glu Asn Glu Lys Tyr Ile Leu 
225                 230                 235                 240 


Lys Gly Ser Asn Thr Glu Leu Thr Val Arg Asn Ile Ile Asn Ser Asp 
                245                 250                 255     


Gly Gly Pro Tyr Val Cys Arg Ala Thr Asn Lys Ala Gly Glu Asp Glu 
            260                 265                 270         


Lys Gln Ala Phe Leu Gln Val Phe Val Gln Pro His Ile Ile Gln Leu 
        275                 280                 285             


Lys Asn Glu Thr Thr Tyr Glu Asn Gly Gln Val Thr Leu Val Cys Asp 
    290                 295                 300                 


Ala Glu Gly Glu Pro Ile Pro Glu Ile Thr Trp Lys Arg Ala Val Asp 
305                 310                 315                 320 


Gly Phe Thr Phe Thr Glu Gly Asp Lys Ser Leu Asp Gly Arg Ile Glu 
                325                 330                 335     


Val Lys Gly Gln His Gly Ser Ser Ser Leu His Ile Lys Asp Val Lys 
            340                 345                 350         


Leu Ser Asp Ser Gly Arg Tyr Asp Cys Glu Ala Ala Ser Arg Ile Gly 
        355                 360                 365             


Gly His Gln Lys Ser Met Tyr Leu Asp Ile Glu Tyr Ala Pro Lys Phe 
    370                 375                 380                 


Ile Ser Asn Gln Thr Ile Tyr Tyr Ser Trp Glu Gly Asn Pro Ile Asn 
385                 390                 395                 400 


Ile Ser Cys Asp Val Lys Ser Asn Pro Pro Ala Ser Ile His Trp Arg 
                405                 410                 415     


Arg Asp Lys Leu Val Leu Pro Ala Lys Asn Thr Thr Asn Leu Lys Thr 
            420                 425                 430         


Tyr Ser Thr Gly Arg Lys Met Ile Leu Glu Ile Ala Pro Thr Ser Asp 
        435                 440                 445             


Asn Asp Phe Gly Arg Tyr Asn Cys Thr Ala Thr Asn His Ile Gly Thr 
    450                 455                 460                 


Arg Phe Gln Glu Tyr Ile Leu Ala Leu Ala Asp Val Pro Ser Ser Pro 
465                 470                 475                 480 


Tyr Gly Val Lys Ile Ile Glu Leu Ser Gln Thr Thr Ala Lys Val Ser 
                485                 490                 495     


Phe Asn Lys Pro Asp Ser His Gly Gly Val Pro Ile His His Tyr Gln 
            500                 505                 510         


Val Asp Val Lys Glu Val Ala Ser Glu Ile Trp Lys Ile Val Arg Ser 
        515                 520                 525             


His Gly Val Gln Thr Met Val Val Leu Asn Asn Leu Glu Pro Asn Thr 
    530                 535                 540                 


Thr Tyr Glu Ile Arg Val Ala Ala Val Asn Gly Lys Gly Gln Gly Asp 
545                 550                 555                 560 


Tyr Ser Lys Ile Glu Ile Phe Gln Thr Leu Pro Val Arg Glu Pro Ser 
                565                 570                 575     


Pro Pro Ser Ile His Gly Gln Pro Ser Ser Gly Lys Ser Phe Lys Leu 
            580                 585                 590         


Ser Ile Thr Lys Gln Asp Asp Gly Gly Ala Pro Ile Leu Glu Tyr Ile 
        595                 600                 605             


Val Lys Tyr Arg Ser Lys Asp Lys Glu Asp Gln Trp Leu Glu Lys Lys 
    610                 615                 620                 


Val Gln Gly Asn Lys Asp His Ile Ile Leu Glu His Leu Gln Trp Thr 
625                 630                 635                 640 


Met Gly Tyr Glu Val Gln Ile Thr Ala Ala Asn Arg Leu Gly Tyr Ser 
                645                 650                 655     


Glu Pro Thr Val Tyr Glu Phe Ser Met Pro Pro Lys Pro Asn Ile Ile 
            660                 665                 670         


Lys Asp Thr Leu Phe Asn 
        675             


<210>  976
<211>  1299
<212>  PRT
<213>  Homo Sapiens

<400>  976

Glu Gln Gly Thr Gln Asp Ile Thr Asp Ala Ser Glu Arg Gly Leu His 
1               5                   10                  15      


Met Gln Lys Leu Gly Ser Gly Ser Val Gln Ala Ala Leu Ala Glu Leu 
            20                  25                  30          


Val Ala Leu Pro Cys Leu Phe Thr Leu Gln Pro Arg Pro Ser Ala Ala 
        35                  40                  45              


Arg Asp Ala Pro Arg Ile Lys Trp Thr Lys Val Arg Thr Ala Ser Gly 
    50                  55                  60                  


Gln Arg Gln Asp Leu Pro Ile Leu Val Ala Lys Asp Asn Val Val Arg 
65                  70                  75                  80  


Val Ala Lys Ser Trp Gln Gly Arg Val Ser Leu Pro Ser Tyr Pro Arg 
                85                  90                  95      


Arg Arg Ala Asn Ala Thr Leu Leu Leu Gly Pro Leu Arg Ala Ser Asp 
            100                 105                 110         


Ser Gly Leu Tyr Arg Cys Gln Val Val Arg Gly Ile Glu Asp Glu Gln 
        115                 120                 125             


Asp Leu Val Pro Leu Glu Val Thr Gly Val Val Phe His Tyr Arg Ser 
    130                 135                 140                 


Ala Arg Asp Arg Tyr Ala Leu Thr Phe Ala Glu Ala Gln Glu Ala Cys 
145                 150                 155                 160 


Arg Leu Ser Ser Ala Ile Ile Ala Ala Pro Arg His Leu Gln Ala Ala 
                165                 170                 175     


Phe Glu Asp Gly Phe Asp Asn Cys Asp Ala Gly Trp Leu Ser Asp Arg 
            180                 185                 190         


Thr Val Arg Tyr Pro Ile Thr Gln Ser Arg Pro Gly Cys Tyr Gly Asp 
        195                 200                 205             


Arg Ser Ser Leu Pro Gly Val Arg Ser Tyr Gly Arg Arg Asn Pro Gln 
    210                 215                 220                 


Glu Leu Tyr Asp Val Tyr Cys Phe Ala Arg Glu Leu Gly Gly Glu Val 
225                 230                 235                 240 


Phe Tyr Val Gly Pro Ala Arg Arg Leu Thr Leu Ala Gly Ala Arg Ala 
                245                 250                 255     


Gln Cys Arg Arg Gln Gly Ala Ala Leu Ala Ser Val Gly Gln Leu His 
            260                 265                 270         


Leu Ala Trp His Glu Gly Leu Asp Gln Cys Asp Pro Gly Trp Leu Ala 
        275                 280                 285             


Asp Gly Ser Val Arg Tyr Pro Ile Gln Thr Pro Arg Arg Arg Cys Gly 
    290                 295                 300                 


Gly Pro Ala Pro Gly Val Arg Thr Val Tyr Arg Phe Ala Asn Arg Thr 
305                 310                 315                 320 


Gly Phe Pro Ser Pro Ala Glu Arg Phe Asp Ala Tyr Cys Phe Arg Ala 
                325                 330                 335     


His His Pro Thr Ser Gln His Gly Asp Leu Glu Thr Pro Ser Ser Gly 
            340                 345                 350         


Asp Glu Gly Glu Ile Leu Ser Ala Glu Gly Pro Pro Val Arg Glu Leu 
        355                 360                 365             


Glu Pro Thr Leu Glu Glu Glu Glu Val Val Thr Pro Asp Phe Gln Glu 
    370                 375                 380                 


Pro Leu Val Ser Ser Gly Glu Glu Glu Thr Leu Ile Leu Glu Glu Lys 
385                 390                 395                 400 


Gln Glu Ser Gln Gln Thr Leu Ser Pro Thr Pro Gly Asp Pro Met Leu 
                405                 410                 415     


Ala Ser Trp Pro Thr Gly Glu Val Trp Leu Ser Thr Val Ala Pro Ser 
            420                 425                 430         


Pro Ser Asp Met Gly Ala Gly Thr Ala Ala Ser Ser His Thr Glu Val 
        435                 440                 445             


Ala Pro Thr Asp Pro Met Pro Arg Arg Arg Gly Arg Phe Lys Gly Leu 
    450                 455                 460                 


Asn Gly Arg Tyr Phe Gln Gln Gln Glu Pro Glu Pro Gly Leu Gln Gly 
465                 470                 475                 480 


Gly Met Glu Ala Ser Ala Gln Pro Pro Thr Ser Glu Ala Ala Val Asn 
                485                 490                 495     


Gln Met Glu Pro Pro Leu Ala Met Ala Val Thr Glu Met Leu Gly Ser 
            500                 505                 510         


Gly Gln Ser Arg Ser Pro Trp Ala Asp Leu Thr Asn Glu Val Asp Met 
        515                 520                 525             


Pro Gly Ala Gly Ser Ala Gly Gly Lys Ser Ser Pro Glu Pro Trp Leu 
    530                 535                 540                 


Trp Pro Pro Thr Met Val Pro Pro Ser Ile Ser Gly His Ser Arg Ala 
545                 550                 555                 560 


Pro Val Leu Glu Leu Glu Lys Ala Glu Gly Pro Ser Ala Arg Pro Ala 
                565                 570                 575     


Thr Pro Asp Leu Phe Trp Ser Pro Leu Glu Ala Thr Val Ser Ala Pro 
            580                 585                 590         


Ser Pro Ala Pro Trp Glu Ala Phe Pro Val Ala Thr Ser Pro Asp Leu 
        595                 600                 605             


Pro Met Met Ala Met Leu Arg Gly Pro Lys Glu Trp Met Leu Pro His 
    610                 615                 620                 


Pro Thr Pro Ile Ser Thr Glu Ala Asn Arg Val Glu Ala His Gly Glu 
625                 630                 635                 640 


Ala Thr Ala Thr Ala Pro Pro Ser Pro Ala Ala Glu Thr Lys Val Tyr 
                645                 650                 655     


Ser Leu Pro Leu Ser Leu Thr Pro Thr Gly Gln Gly Gly Glu Ala Met 
            660                 665                 670         


Pro Thr Thr Pro Glu Ser Pro Arg Ala Asp Phe Arg Glu Thr Gly Glu 
        675                 680                 685             


Thr Ser Pro Ala Gln Val Asn Lys Ala Glu His Ser Ser Ser Ser Pro 
    690                 695                 700                 


Trp Pro Ser Val Asn Arg Asn Val Ala Val Gly Phe Val Pro Thr Glu 
705                 710                 715                 720 


Thr Ala Thr Glu Pro Thr Gly Leu Arg Gly Ile Pro Gly Ser Glu Ser 
                725                 730                 735     


Gly Val Phe Asp Thr Ala Glu Ser Pro Thr Ser Gly Leu Gln Ala Thr 
            740                 745                 750         


Val Asp Glu Val Gln Asp Pro Trp Pro Ser Val Tyr Ser Lys Gly Leu 
        755                 760                 765             


Asp Ala Ser Ser Pro Ser Ala Pro Leu Gly Ser Pro Gly Val Phe Leu 
    770                 775                 780                 


Val Pro Lys Val Thr Pro Asn Leu Glu Pro Trp Val Ala Thr Asp Glu 
785                 790                 795                 800 


Gly Pro Thr Val Asn Pro Met Asp Ser Thr Val Thr Pro Ala Pro Ser 
                805                 810                 815     


Asp Ala Ser Gly Ile Trp Glu Pro Gly Ser Gln Val Phe Glu Glu Ala 
            820                 825                 830         


Glu Ser Thr Thr Leu Ser Pro Gln Val Ala Leu Asp Thr Ser Ile Val 
        835                 840                 845             


Thr Pro Leu Thr Thr Leu Glu Gln Gly Asp Lys Val Gly Val Pro Ala 
    850                 855                 860                 


Met Ser Thr Leu Gly Ser Ser Ser Ser Gln Pro His Pro Glu Pro Glu 
865                 870                 875                 880 


Asp Gln Val Glu Thr Gln Gly Thr Ser Gly Ala Ser Val Pro Pro His 
                885                 890                 895     


Gln Ser Ser Pro Leu Gly Lys Pro Ala Val Pro Pro Gly Thr Pro Thr 
            900                 905                 910         


Ala Ala Ser Val Gly Glu Ser Ala Ser Val Ser Ser Gly Glu Pro Thr 
        915                 920                 925             


Val Pro Trp Asp Pro Ser Ser Thr Leu Leu Pro Val Thr Leu Gly Ile 
    930                 935                 940                 


Glu Asp Phe Glu Leu Glu Val Leu Ala Gly Ser Pro Gly Val Glu Ser 
945                 950                 955                 960 


Phe Trp Glu Glu Val Ala Ser Gly Glu Glu Pro Ala Leu Pro Gly Thr 
                965                 970                 975     


Pro Met Asn Ala Gly Ala Glu Glu Val His Ser Asp Pro Cys Glu Asn 
            980                 985                 990         


Asn Pro Cys Leu His Gly Gly Thr  Cys Asn Ala Asn Gly  Thr Met Tyr 
        995                 1000                 1005             


Gly Cys  Ser Cys Asp Gln Gly  Phe Ala Gly Glu Asn  Cys Glu Ile 
    1010                 1015                 1020             


Asp Ile  Asp Asp Cys Leu Cys  Ser Pro Cys Glu Asn  Gly Gly Thr 
    1025                 1030                 1035             


Cys Ile  Asp Glu Val Asn Gly  Phe Val Cys Leu Cys  Leu Pro Ser 
    1040                 1045                 1050             


Tyr Gly  Gly Ser Phe Cys Glu  Lys Asp Thr Glu Gly  Cys Asp Arg 
    1055                 1060                 1065             


Gly Trp  His Lys Phe Gln Gly  His Cys Tyr Arg Tyr  Phe Ala His 
    1070                 1075                 1080             


Arg Arg  Ala Trp Glu Asp Ala  Glu Lys Asp Cys Arg  Arg Arg Ser 
    1085                 1090                 1095             


Gly His  Leu Thr Ser Val His  Ser Pro Glu Glu His  Ser Phe Ile 
    1100                 1105                 1110             


Asn Ser  Phe Gly His Glu Asn  Thr Trp Ile Gly Leu  Asn Asp Arg 
    1115                 1120                 1125             


Ile Val  Glu Arg Asp Phe Gln  Trp Thr Asp Asn Thr  Gly Leu Gln 
    1130                 1135                 1140             


Phe Glu  Asn Trp Arg Glu Asn  Gln Pro Asp Asn Phe  Phe Ala Gly 
    1145                 1150                 1155             


Gly Glu  Asp Cys Val Val Met  Val Ala His Glu Ser  Gly Arg Trp 
    1160                 1165                 1170             


Asn Asp  Val Pro Cys Asn Tyr  Asn Leu Pro Tyr Val  Cys Lys Lys 
    1175                 1180                 1185             


Gly Thr  Val Leu Cys Gly Pro  Pro Pro Ala Val Glu  Asn Ala Ser 
    1190                 1195                 1200             


Leu Ile  Gly Ala Arg Lys Ala  Lys Tyr Asn Val His  Ala Thr Val 
    1205                 1210                 1215             


Arg Tyr  Gln Cys Asn Glu Gly  Phe Ala Gln His His  Val Ala Thr 
    1220                 1225                 1230             


Ile Arg  Cys Arg Ser Asn Gly  Lys Trp Asp Arg Pro  Gln Ile Val 
    1235                 1240                 1245             


Cys Thr  Lys Pro Arg Arg Ser  His Arg Met Arg Arg  His His His 
    1250                 1255                 1260             


His His  Gln His His His Gln  His His His His Lys  Ser Arg Lys 
    1265                 1270                 1275             


Glu Arg  Arg Lys His Lys Lys  His Pro Thr Glu Asp  Trp Glu Lys 
    1280                 1285                 1290             


Asp Glu  Gly Asn Phe Cys 
    1295                 


<210>  977
<211>  236
<212>  PRT
<213>  Homo Sapiens

<400>  977

Gln Gln Gln Thr Leu Pro Lys Pro Phe Ile Trp Ala Glu Pro His Phe 
1               5                   10                  15      


Met Val Pro Lys Glu Lys Gln Val Thr Ile Cys Cys Gln Gly Asn Tyr 
            20                  25                  30          


Gly Ala Val Glu Tyr Gln Leu His Phe Glu Gly Ser Leu Phe Ala Val 
        35                  40                  45              


Asp Arg Pro Lys Pro Pro Glu Arg Ile Asn Lys Val Lys Phe Tyr Ile 
    50                  55                  60                  


Pro Asp Met Asn Ser Arg Met Ala Gly Gln Tyr Ser Cys Ile Tyr Arg 
65                  70                  75                  80  


Val Gly Glu Leu Trp Ser Glu Pro Ser Asn Leu Leu Asp Leu Val Val 
                85                  90                  95      


Thr Glu Met Tyr Asp Thr Pro Thr Leu Ser Val His Pro Gly Pro Glu 
            100                 105                 110         


Val Ile Ser Gly Glu Lys Val Thr Phe Tyr Cys Arg Leu Asp Thr Ala 
        115                 120                 125             


Thr Ser Met Phe Leu Leu Leu Lys Glu Gly Arg Ser Ser His Val Gln 
    130                 135                 140                 


Arg Gly Tyr Gly Lys Val Gln Ala Glu Phe Pro Leu Gly Pro Val Thr 
145                 150                 155                 160 


Thr Ala His Arg Gly Thr Tyr Arg Cys Phe Gly Ser Tyr Asn Asn His 
                165                 170                 175     


Ala Trp Ser Phe Pro Ser Glu Pro Val Lys Leu Leu Val Thr Gly Asp 
            180                 185                 190         


Ile Glu Asn Thr Ser Leu Ala Pro Glu Asp Pro Thr Phe Pro Asp Thr 
        195                 200                 205             


Trp Gly Thr Tyr Leu Leu Thr Thr Glu Thr Gly Leu Gln Lys Asp His 
    210                 215                 220                 


Ala Leu Trp Asp His Thr Ala Gln Asn Leu Leu Arg 
225                 230                 235     


<210>  978
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  978

Gln Ser Lys Ala Gln Val Leu Gln Ser Val Ala Gly Gln Thr Leu Thr 
1               5                   10                  15      


Val Arg Cys Gln Tyr Pro Pro Thr Gly Ser Leu Tyr Glu Lys Lys Gly 
            20                  25                  30          


Trp Cys Lys Glu Ala Ser Ala Leu Val Cys Ile Arg Leu Val Thr Ser 
        35                  40                  45              


Ser Lys Pro Arg Thr Met Ala Trp Thr Ser Arg Phe Thr Ile Trp Asp 
    50                  55                  60                  


Asp Pro Asp Ala Gly Phe Phe Thr Val Thr Met Thr Asp Leu Arg Glu 
65                  70                  75                  80  


Glu Asp Ser Gly His Tyr Trp Cys Arg Ile Tyr Arg Pro Ser Asp Asn 
                85                  90                  95      


Ser Val Ser Lys Ser Val Arg Phe Tyr Leu Val Val Ser Pro Ala Ser 
            100                 105                 110         


Ala Ser Thr Gln Thr Ser Trp Thr Pro Arg Asp Leu Val Ser Ser Gln 
        115                 120                 125             


Thr Gln Thr Gln Ser Cys Val Pro Pro Thr Ala Gly Ala Arg Gln Ala 
    130                 135                 140                 


Pro Glu Ser Pro Ser Thr Ile Pro Val Pro Ser Gln Pro Gln Asn Ser 
145                 150                 155                 160 


Thr Leu Arg Pro Gly Pro Ala Ala Pro Ile Ala 
                165                 170     


<210>  979
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  979

Leu Trp Val Ser Gln Pro Pro Glu Ile Arg Thr Leu Glu Gly Ser Ser 
1               5                   10                  15      


Ala Phe Leu Pro Cys Ser Phe Asn Ala Ser Gln Gly Arg Leu Ala Ile 
            20                  25                  30          


Gly Ser Val Thr Trp Phe Arg Asp Glu Val Val Pro Gly Lys Glu Val 
        35                  40                  45              


Arg Asn Gly Thr Pro Glu Phe Arg Gly Arg Leu Ala Pro Leu Ala Ser 
    50                  55                  60                  


Ser Arg Phe Leu His Asp His Gln Ala Glu Leu His Ile Arg Asp Val 
65                  70                  75                  80  


Arg Gly His Asp Ala Ser Ile Tyr Val Cys Arg Val Glu Val Leu Gly 
                85                  90                  95      


Leu Gly Val Gly Thr Gly Asn Gly Thr Arg Leu Val Val Glu Lys Glu 
            100                 105                 110         


His Pro Gln Leu Gly 
        115         


<210>  980
<211>  549
<212>  PRT
<213>  Homo Sapiens

<400>  980

Gln Lys Leu Pro Thr Arg Asp Glu Glu Leu Phe Gln Met Gln Ile Arg 
1               5                   10                  15      


Asp Lys Ala Phe Phe His Asp Ser Ser Val Ile Pro Asp Gly Ala Glu 
            20                  25                  30          


Ile Ser Ser Tyr Leu Phe Arg Asp Thr Pro Lys Arg Tyr Phe Phe Val 
        35                  40                  45              


Val Glu Glu Asp Asn Thr Pro Leu Ser Val Thr Val Thr Pro Cys Asp 
    50                  55                  60                  


Ala Pro Leu Glu Trp Lys Leu Ser Leu Gln Glu Leu Pro Glu Asp Arg 
65                  70                  75                  80  


Ser Gly Glu Gly Ser Gly Asp Leu Glu Pro Leu Glu Gln Gln Lys Gln 
                85                  90                  95      


Gln Ile Ile Asn Glu Glu Gly Thr Glu Leu Phe Ser Tyr Lys Gly Asn 
            100                 105                 110         


Asp Val Glu Tyr Phe Ile Ser Ser Ser Ser Pro Ser Gly Leu Tyr Gln 
        115                 120                 125             


Leu Asp Leu Leu Ser Thr Glu Lys Asp Thr His Phe Lys Val Tyr Ala 
    130                 135                 140                 


Thr Thr Thr Pro Glu Ser Asp Gln Pro Tyr Pro Glu Leu Pro Tyr Asp 
145                 150                 155                 160 


Pro Arg Val Asp Val Thr Ser Leu Gly Arg Thr Thr Val Thr Leu Ala 
                165                 170                 175     


Trp Lys Pro Ser Pro Thr Ala Ser Leu Leu Lys Gln Pro Ile Gln Tyr 
            180                 185                 190         


Cys Val Val Ile Asn Lys Glu His Asn Phe Lys Ser Leu Cys Ala Val 
        195                 200                 205             


Glu Ala Lys Leu Ser Ala Asp Asp Ala Phe Met Met Ala Pro Lys Pro 
    210                 215                 220                 


Gly Leu Asp Phe Ser Pro Phe Asp Phe Ala His Phe Gly Phe Pro Ser 
225                 230                 235                 240 


Asp Asn Ser Gly Lys Glu Arg Ser Phe Gln Ala Lys Pro Ser Pro Lys 
                245                 250                 255     


Leu Gly Arg His Val Tyr Ser Arg Pro Lys Val Asp Ile Gln Lys Ile 
            260                 265                 270         


Cys Ile Gly Asn Lys Asn Ile Phe Thr Val Ser Asp Leu Lys Pro Asp 
        275                 280                 285             


Thr Gln Tyr Tyr Phe Asp Val Phe Val Val Asn Ile Asn Ser Asn Met 
    290                 295                 300                 


Ser Thr Ala Tyr Val Gly Thr Phe Ala Arg Thr Lys Glu Glu Ala Lys 
305                 310                 315                 320 


Gln Lys Thr Val Glu Leu Lys Asp Gly Lys Ile Thr Asp Val Phe Val 
                325                 330                 335     


Lys Arg Lys Gly Ala Lys Phe Leu Arg Phe Ala Pro Val Ser Ser His 
            340                 345                 350         


Gln Lys Val Thr Phe Phe Ile His Ser Cys Leu Asp Ala Val Gln Ile 
        355                 360                 365             


Gln Val Arg Arg Asp Gly Lys Leu Leu Leu Ser Gln Asn Val Glu Gly 
    370                 375                 380                 


Ile Gln Gln Phe Gln Leu Arg Gly Lys Pro Lys Ala Lys Tyr Leu Val 
385                 390                 395                 400 


Arg Leu Lys Gly Asn Lys Lys Gly Ala Ser Met Leu Lys Ile Leu Ala 
                405                 410                 415     


Thr Thr Arg Pro Thr Lys Gln Ser Phe Pro Ser Leu Pro Glu Asp Thr 
            420                 425                 430         


Arg Ile Lys Ala Phe Asp Lys Leu Arg Thr Cys Ser Ser Ala Thr Val 
        435                 440                 445             


Ala Trp Leu Gly Thr Gln Glu Arg Asn Lys Phe Cys Ile Tyr Lys Lys 
    450                 455                 460                 


Glu Val Asp Asp Asn Tyr Asn Glu Asp Gln Lys Lys Arg Glu Gln Asn 
465                 470                 475                 480 


Gln Cys Leu Gly Pro Asp Ile Arg Lys Lys Ser Glu Lys Val Leu Cys 
                485                 490                 495     


Lys Tyr Phe His Ser Gln Asn Leu Gln Lys Ala Val Thr Thr Glu Thr 
            500                 505                 510         


Ile Lys Gly Leu Gln Pro Gly Lys Ser Tyr Leu Leu Asp Val Tyr Val 
        515                 520                 525             


Ile Gly His Gly Gly His Ser Val Lys Tyr Gln Ser Lys Val Val Lys 
    530                 535                 540                 


Thr Arg Lys Phe Cys 
545                 


<210>  981
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  981

Met Gln Val His Leu Thr Val Gln Val Pro Pro Lys Ile Tyr Asp Ile 
1               5                   10                  15      


Ser Asn Asp Met Thr Val Asn Glu Gly Thr Asn Val Thr Leu Thr Cys 
            20                  25                  30          


Leu Ala Thr Gly Lys Pro Glu Pro Ser Ile Ser Trp Arg His Ile Ser 
        35                  40                  45              


Pro Ser Ala Lys Pro Phe Glu Asn Gly Gln Tyr Leu Asp Ile Tyr Gly 
    50                  55                  60                  


Ile Thr Arg Asp Gln Ala Gly Glu Tyr Glu Cys Ser Ala Glu Asn Asp 
65                  70                  75                  80  


Val Ser Phe Pro Asp Val Arg Lys Val Lys Val Val Val Asn Phe Ala 
                85                  90                  95      


Pro Thr Ile Gln Glu Ile Lys Ser Gly Thr Val Thr Pro Gly Arg Ser 
            100                 105                 110         


Gly Leu Ile Arg Cys Glu Gly Ala Gly Val Pro Pro Pro Ala Phe Glu 
        115                 120                 125             


Trp Tyr Lys Gly Glu Lys Lys Leu Phe Asn Gly Gln Gln Gly Ile Ile 
    130                 135                 140                 


Ile Gln Asn Phe Ser Thr Arg Ser Ile Leu Thr Val Thr Asn Val Thr 
145                 150                 155                 160 


Gln Glu His Phe Gly Asn Tyr Thr Cys Val Ala Ala Asn Lys Leu Gly 
                165                 170                 175     


Thr Thr Asn Ala Ser Leu Pro Leu Asn Pro Pro Ser Thr Ala Gln Tyr 
            180                 185                 190         


Gly Ile Thr Gly 
        195     


<210>  982
<211>  789
<212>  PRT
<213>  Homo Sapiens

<400>  982

Phe Gly Met Asp Pro Asp Leu Gln Met Asp Ile Val Thr Glu Leu Asp 
1               5                   10                  15      


Leu Val Asn Thr Thr Leu Gly Val Ala Gln Val Ser Gly Met His Asn 
            20                  25                  30          


Ala Ser Lys Ala Phe Leu Phe Gln Asp Ile Glu Arg Glu Ile His Ala 
        35                  40                  45              


Ala Pro His Val Ser Glu Lys Leu Ile Gln Leu Phe Gln Asn Lys Ser 
    50                  55                  60                  


Glu Phe Thr Ile Leu Ala Thr Val Gln Gln Lys Pro Ser Thr Ser Gly 
65                  70                  75                  80  


Val Ile Leu Ser Ile Arg Glu Leu Glu His Ser Tyr Phe Glu Leu Glu 
                85                  90                  95      


Ser Ser Gly Leu Arg Asp Glu Ile Arg Tyr His Tyr Ile His Asn Gly 
            100                 105                 110         


Lys Pro Arg Thr Glu Ala Leu Pro Tyr Arg Met Ala Asp Gly Gln Trp 
        115                 120                 125             


His Lys Val Ala Leu Ser Val Ser Ala Ser His Leu Leu Leu His Val 
    130                 135                 140                 


Asp Cys Asn Arg Ile Tyr Glu Arg Val Ile Asp Pro Pro Asp Thr Asn 
145                 150                 155                 160 


Leu Pro Pro Gly Ile Asn Leu Trp Leu Gly Gln Arg Asn Gln Lys His 
                165                 170                 175     


Gly Leu Phe Lys Gly Ile Ile Gln Asp Gly Lys Ile Ile Phe Met Pro 
            180                 185                 190         


Asn Gly Tyr Ile Thr Gln Cys Pro Asn Leu Asn His Thr Cys Pro Thr 
        195                 200                 205             


Cys Ser Asp Phe Leu Ser Leu Val Gln Gly Ile Met Asp Leu Gln Glu 
    210                 215                 220                 


Leu Leu Ala Lys Met Thr Ala Lys Leu Asn Tyr Ala Glu Thr Arg Leu 
225                 230                 235                 240 


Ser Gln Leu Glu Asn Cys His Cys Glu Lys Thr Cys Gln Val Ser Gly 
                245                 250                 255     


Leu Leu Tyr Arg Asp Gln Asp Ser Trp Val Asp Gly Asp His Cys Arg 
            260                 265                 270         


Asn Cys Thr Cys Lys Ser Gly Ala Val Glu Cys Arg Arg Met Ser Cys 
        275                 280                 285             


Pro Pro Leu Asn Cys Ser Pro Asp Ser Leu Pro Val His Ile Ala Gly 
    290                 295                 300                 


Gln Cys Cys Lys Val Cys Arg Pro Lys Cys Ile Tyr Gly Gly Lys Val 
305                 310                 315                 320 


Leu Ala Glu Gly Gln Arg Ile Leu Thr Lys Ser Cys Arg Glu Cys Arg 
                325                 330                 335     


Gly Gly Val Leu Val Lys Ile Thr Glu Met Cys Pro Pro Leu Asn Cys 
            340                 345                 350         


Ser Glu Lys Asp His Ile Leu Pro Glu Asn Gln Cys Cys Arg Val Cys 
        355                 360                 365             


Arg Gly His Asn Phe Cys Ala Glu Gly Pro Lys Cys Gly Glu Asn Ser 
    370                 375                 380                 


Glu Cys Lys Asn Trp Asn Thr Lys Ala Thr Cys Glu Cys Lys Ser Gly 
385                 390                 395                 400 


Tyr Ile Ser Val Gln Gly Asp Ser Ala Tyr Cys Glu Asp Ile Asp Glu 
                405                 410                 415     


Cys Ala Ala Lys Met His Tyr Cys His Ala Asn Thr Val Cys Val Asn 
            420                 425                 430         


Leu Pro Gly Leu Tyr Arg Cys Asp Cys Val Pro Gly Tyr Ile Arg Val 
        435                 440                 445             


Asp Asp Phe Ser Cys Thr Glu His Asp Glu Cys Gly Ser Gly Gln His 
    450                 455                 460                 


Asn Cys Asp Glu Asn Ala Ile Cys Thr Asn Thr Val Gln Gly His Ser 
465                 470                 475                 480 


Cys Thr Cys Lys Pro Gly Tyr Val Gly Asn Gly Thr Ile Cys Arg Ala 
                485                 490                 495     


Phe Cys Glu Glu Gly Cys Arg Tyr Gly Gly Thr Cys Val Ala Pro Asn 
            500                 505                 510         


Lys Cys Val Cys Pro Ser Gly Phe Thr Gly Ser His Cys Glu Lys Asp 
        515                 520                 525             


Ile Asp Glu Cys Ser Glu Gly Ile Ile Glu Cys His Asn His Ser Arg 
    530                 535                 540                 


Cys Val Asn Leu Pro Gly Trp Tyr His Cys Glu Cys Arg Ser Gly Phe 
545                 550                 555                 560 


His Asp Asp Gly Thr Tyr Ser Leu Ser Gly Glu Ser Cys Ile Asp Ile 
                565                 570                 575     


Asp Glu Cys Ala Leu Arg Thr His Thr Cys Trp Asn Asp Ser Ala Cys 
            580                 585                 590         


Ile Asn Leu Ala Gly Gly Phe Asp Cys Leu Cys Pro Ser Gly Pro Ser 
        595                 600                 605             


Cys Ser Gly Asp Cys Pro His Glu Gly Gly Leu Lys His Asn Gly Gln 
    610                 615                 620                 


Val Trp Thr Leu Lys Glu Asp Arg Cys Ser Val Cys Ser Cys Lys Asp 
625                 630                 635                 640 


Gly Lys Ile Phe Cys Arg Arg Thr Ala Cys Asp Cys Gln Asn Pro Ser 
                645                 650                 655     


Ala Asp Leu Phe Cys Cys Pro Glu Cys Asp Thr Arg Val Thr Ser Gln 
            660                 665                 670         


Cys Leu Asp Gln Asn Gly His Lys Leu Tyr Arg Ser Gly Asp Asn Trp 
        675                 680                 685             


Thr His Ser Cys Gln Gln Cys Arg Cys Leu Glu Gly Glu Val Asp Cys 
    690                 695                 700                 


Trp Pro Leu Thr Cys Pro Asn Leu Ser Cys Glu Tyr Thr Ala Ile Leu 
705                 710                 715                 720 


Glu Gly Glu Cys Cys Pro Arg Cys Val Ser Asp Pro Cys Leu Ala Asp 
                725                 730                 735     


Asn Ile Thr Tyr Asp Ile Arg Lys Thr Cys Leu Asp Ser Tyr Gly Val 
            740                 745                 750         


Ser Arg Leu Ser Gly Ser Val Trp Thr Met Ala Gly Ser Pro Cys Thr 
        755                 760                 765             


Thr Cys Lys Cys Lys Asn Gly Arg Val Cys Cys Ser Val Asp Phe Glu 
    770                 775                 780                 


Cys Leu Gln Asn Asn 
785                 


<210>  983
<211>  795
<212>  PRT
<213>  Homo Sapiens

<400>  983

Leu Gly Val Asp Pro Ser Leu Gln Ile Asp Val Leu Thr Glu Leu Glu 
1               5                   10                  15      


Leu Gly Glu Ser Thr Thr Gly Val Arg Gln Val Pro Gly Leu His Asn 
            20                  25                  30          


Gly Thr Lys Ala Phe Leu Phe Gln Asp Thr Pro Arg Ser Ile Lys Ala 
        35                  40                  45              


Ser Thr Ala Thr Ala Glu Gln Phe Phe Gln Lys Leu Arg Asn Lys His 
    50                  55                  60                  


Glu Phe Thr Ile Leu Val Thr Leu Lys Gln Thr His Leu Asn Ser Gly 
65                  70                  75                  80  


Val Ile Leu Ser Ile His His Leu Asp His Arg Tyr Leu Glu Leu Glu 
                85                  90                  95      


Ser Ser Gly His Arg Asn Glu Val Arg Leu His Tyr Arg Ser Gly Ser 
            100                 105                 110         


His Arg Pro His Thr Glu Val Phe Pro Tyr Ile Leu Ala Asp Asp Lys 
        115                 120                 125             


Trp His Lys Leu Ser Leu Ala Ile Ser Ala Ser His Leu Ile Leu His 
    130                 135                 140                 


Ile Asp Cys Asn Lys Ile Tyr Glu Arg Val Val Glu Lys Pro Ser Thr 
145                 150                 155                 160 


Asp Leu Pro Leu Gly Thr Thr Phe Trp Leu Gly Gln Arg Asn Asn Ala 
                165                 170                 175     


His Gly Tyr Phe Lys Gly Ile Met Gln Asp Val Gln Leu Leu Val Met 
            180                 185                 190         


Pro Gln Gly Phe Ile Ala Gln Cys Pro Asp Leu Asn Arg Thr Cys Pro 
        195                 200                 205             


Thr Cys Asn Asp Phe His Gly Leu Val Gln Lys Ile Met Glu Leu Gln 
    210                 215                 220                 


Asp Ile Leu Ala Lys Thr Ser Ala Lys Leu Ser Arg Ala Glu Gln Arg 
225                 230                 235                 240 


Met Asn Arg Leu Asp Gln Cys Tyr Cys Glu Arg Thr Cys Thr Met Lys 
                245                 250                 255     


Gly Thr Thr Tyr Arg Glu Phe Glu Ser Trp Ile Asp Gly Cys Lys Asn 
            260                 265                 270         


Cys Thr Cys Leu Asn Gly Thr Ile Gln Cys Glu Thr Leu Ile Cys Pro 
        275                 280                 285             


Asn Pro Asp Cys Pro Leu Lys Ser Ala Leu Ala Tyr Val Asp Gly Lys 
    290                 295                 300                 


Cys Cys Lys Glu Cys Lys Ser Ile Cys Gln Phe Gln Gly Arg Thr Tyr 
305                 310                 315                 320 


Phe Glu Gly Glu Arg Asn Thr Val Tyr Ser Ser Ser Gly Val Cys Val 
                325                 330                 335     


Leu Tyr Glu Cys Lys Asp Gln Thr Met Lys Leu Val Glu Ser Ser Gly 
            340                 345                 350         


Cys Pro Ala Leu Asp Cys Pro Glu Ser His Gln Ile Thr Leu Ser His 
        355                 360                 365             


Ser Cys Cys Lys Val Cys Lys Gly Tyr Asp Phe Cys Ser Glu Arg His 
    370                 375                 380                 


Asn Cys Met Glu Asn Ser Ile Cys Arg Asn Leu Asn Asp Arg Ala Val 
385                 390                 395                 400 


Cys Ser Cys Arg Asp Gly Phe Arg Ala Leu Arg Glu Asp Asn Ala Tyr 
                405                 410                 415     


Cys Glu Asp Ile Asp Glu Cys Ala Glu Gly Arg His Tyr Cys Arg Glu 
            420                 425                 430         


Asn Thr Met Cys Val Asn Thr Pro Gly Ser Phe Met Cys Ile Cys Lys 
        435                 440                 445             


Thr Gly Tyr Ile Arg Ile Asp Asp Tyr Ser Cys Thr Glu His Asp Glu 
    450                 455                 460                 


Cys Ile Thr Asn Gln His Asn Cys Asp Glu Asn Ala Leu Cys Phe Asn 
465                 470                 475                 480 


Thr Val Gly Gly His Asn Cys Val Cys Lys Pro Gly Tyr Thr Gly Asn 
                485                 490                 495     


Gly Thr Thr Cys Lys Ala Phe Cys Lys Asp Gly Cys Arg Asn Gly Gly 
            500                 505                 510         


Ala Cys Ile Ala Ala Asn Val Cys Ala Cys Pro Gln Gly Phe Thr Gly 
        515                 520                 525             


Pro Ser Cys Glu Thr Asp Ile Asp Glu Cys Ser Asp Gly Phe Val Gln 
    530                 535                 540                 


Cys Asp Ser Arg Ala Asn Cys Ile Asn Leu Pro Gly Trp Tyr His Cys 
545                 550                 555                 560 


Glu Cys Arg Asp Gly Tyr His Asp Asn Gly Met Phe Ser Pro Ser Gly 
                565                 570                 575     


Glu Ser Cys Glu Asp Ile Asp Glu Cys Gly Thr Gly Arg His Ser Cys 
            580                 585                 590         


Ala Asn Asp Thr Ile Cys Phe Asn Leu Asp Gly Gly Tyr Asp Cys Arg 
        595                 600                 605             


Cys Pro His Gly Lys Asn Cys Thr Gly Asp Cys Ile His Asp Gly Lys 
    610                 615                 620                 


Val Lys His Asn Gly Gln Ile Trp Val Leu Glu Asn Asp Arg Cys Ser 
625                 630                 635                 640 


Val Cys Ser Cys Gln Asn Gly Phe Val Met Cys Arg Arg Met Val Cys 
                645                 650                 655     


Asp Cys Glu Asn Pro Thr Val Asp Leu Phe Cys Cys Pro Glu Cys Asp 
            660                 665                 670         


Pro Arg Leu Ser Ser Gln Cys Leu His Gln Asn Gly Glu Thr Leu Tyr 
        675                 680                 685             


Asn Ser Gly Asp Thr Trp Val Gln Asn Cys Gln Gln Cys Arg Cys Leu 
    690                 695                 700                 


Gln Gly Glu Val Asp Cys Trp Pro Leu Pro Cys Pro Asp Val Glu Cys 
705                 710                 715                 720 


Glu Phe Ser Ile Leu Pro Glu Asn Glu Cys Cys Pro Arg Cys Val Thr 
                725                 730                 735     


Asp Pro Cys Gln Ala Asp Thr Ile Arg Asn Asp Ile Thr Lys Thr Cys 
            740                 745                 750         


Leu Asp Glu Met Asn Val Val Arg Phe Thr Gly Ser Ser Trp Ile Lys 
        755                 760                 765             


His Gly Thr Glu Cys Thr Leu Cys Gln Cys Lys Asn Gly His Ile Cys 
    770                 775                 780                 


Cys Ser Val Asp Pro Gln Cys Leu Gln Glu Leu 
785                 790                 795 


<210>  984
<211>  1072
<212>  PRT
<213>  Homo Sapiens

<400>  984

Ala Arg Ser Gly Ser Ala Pro Gln Ser Pro Gly Ala Ser Ile Arg Thr 
1               5                   10                  15      


Phe Thr Pro Phe Tyr Phe Leu Val Glu Pro Val Asp Thr Leu Ser Val 
            20                  25                  30          


Arg Gly Ser Ser Val Ile Leu Asn Cys Ser Ala Tyr Ser Glu Pro Ser 
        35                  40                  45              


Pro Lys Ile Glu Trp Lys Lys Asp Gly Thr Phe Leu Asn Leu Val Ser 
    50                  55                  60                  


Asp Asp Arg Arg Gln Leu Leu Pro Asp Gly Ser Leu Phe Ile Ser Asn 
65                  70                  75                  80  


Val Val His Ser Lys His Asn Lys Pro Asp Glu Gly Tyr Tyr Gln Cys 
                85                  90                  95      


Val Ala Thr Val Glu Ser Leu Gly Thr Ile Ile Ser Arg Thr Ala Lys 
            100                 105                 110         


Leu Ile Val Ala Gly Leu Pro Arg Phe Thr Ser Gln Pro Glu Pro Ser 
        115                 120                 125             


Ser Val Tyr Ala Gly Asn Asn Ala Ile Leu Asn Cys Glu Val Asn Ala 
    130                 135                 140                 


Asp Leu Val Pro Phe Val Arg Trp Glu Gln Asn Arg Gln Pro Leu Leu 
145                 150                 155                 160 


Leu Asp Asp Arg Val Ile Lys Leu Pro Ser Gly Met Leu Val Ile Ser 
                165                 170                 175     


Asn Ala Thr Glu Gly Asp Gly Gly Leu Tyr Arg Cys Val Val Glu Ser 
            180                 185                 190         


Gly Gly Pro Pro Lys Tyr Ser Asp Glu Val Glu Leu Lys Val Leu Pro 
        195                 200                 205             


Asp Pro Glu Val Ile Ser Asp Leu Val Phe Leu Lys Gln Pro Ser Pro 
    210                 215                 220                 


Leu Val Arg Val Ile Gly Gln Asp Val Val Leu Pro Cys Val Ala Ser 
225                 230                 235                 240 


Gly Leu Pro Thr Pro Thr Ile Lys Trp Met Lys Asn Glu Glu Ala Leu 
                245                 250                 255     


Asp Thr Glu Ser Ser Glu Arg Leu Val Leu Leu Ala Gly Gly Ser Leu 
            260                 265                 270         


Glu Ile Ser Asp Val Thr Glu Asp Asp Ala Gly Thr Tyr Phe Cys Ile 
        275                 280                 285             


Ala Asp Asn Gly Asn Glu Thr Ile Glu Ala Gln Ala Glu Leu Thr Val 
    290                 295                 300                 


Gln Ala Gln Pro Glu Phe Leu Lys Gln Pro Thr Asn Ile Tyr Ala His 
305                 310                 315                 320 


Glu Ser Met Asp Ile Val Phe Glu Cys Glu Val Thr Gly Lys Pro Thr 
                325                 330                 335     


Pro Thr Val Lys Trp Val Lys Asn Gly Asp Met Val Ile Pro Ser Asp 
            340                 345                 350         


Tyr Phe Lys Ile Val Lys Glu His Asn Leu Gln Val Leu Gly Leu Val 
        355                 360                 365             


Lys Ser Asp Glu Gly Phe Tyr Gln Cys Ile Ala Glu Asn Asp Val Gly 
    370                 375                 380                 


Asn Ala Gln Ala Gly Ala Gln Leu Ile Ile Leu Glu His Ala Pro Ala 
385                 390                 395                 400 


Thr Thr Gly Pro Leu Pro Ser Ala Pro Arg Asp Val Val Ala Ser Leu 
                405                 410                 415     


Val Ser Thr Arg Phe Ile Lys Leu Thr Trp Arg Thr Pro Ala Ser Asp 
            420                 425                 430         


Pro His Gly Asp Asn Leu Thr Tyr Ser Val Phe Tyr Thr Lys Glu Gly 
        435                 440                 445             


Ile Ala Arg Glu Arg Val Glu Asn Thr Ser His Pro Gly Glu Met Gln 
    450                 455                 460                 


Val Thr Ile Gln Asn Leu Met Pro Ala Thr Val Tyr Ile Phe Arg Val 
465                 470                 475                 480 


Met Ala Gln Asn Lys His Gly Ser Gly Glu Ser Ser Ala Pro Leu Arg 
                485                 490                 495     


Val Glu Thr Gln Pro Glu Val Gln Leu Pro Gly Pro Ala Pro Asn Leu 
            500                 505                 510         


Arg Ala Tyr Ala Ala Ser Pro Thr Ser Ile Thr Val Thr Trp Glu Thr 
        515                 520                 525             


Pro Val Ser Gly Asn Gly Glu Ile Gln Asn Tyr Lys Leu Tyr Tyr Met 
    530                 535                 540                 


Glu Lys Gly Thr Asp Lys Glu Gln Asp Val Asp Val Ser Ser His Ser 
545                 550                 555                 560 


Tyr Thr Ile Asn Gly Leu Lys Lys Tyr Thr Glu Tyr Ser Phe Arg Val 
                565                 570                 575     


Val Ala Tyr Asn Lys His Gly Pro Gly Val Ser Thr Pro Asp Val Ala 
            580                 585                 590         


Val Arg Thr Leu Ser Asp Val Pro Ser Ala Ala Pro Gln Asn Leu Ser 
        595                 600                 605             


Leu Glu Val Arg Asn Ser Lys Ser Ile Met Ile His Trp Gln Pro Pro 
    610                 615                 620                 


Ala Pro Ala Thr Gln Asn Gly Gln Ile Thr Gly Tyr Lys Ile Arg Tyr 
625                 630                 635                 640 


Arg Lys Ala Ser Arg Lys Ser Asp Val Thr Glu Thr Leu Val Ser Gly 
                645                 650                 655     


Thr Gln Leu Ser Gln Leu Ile Glu Gly Leu Asp Arg Gly Thr Glu Tyr 
            660                 665                 670         


Asn Phe Arg Val Ala Ala Leu Thr Ile Asn Gly Thr Gly Pro Ala Thr 
        675                 680                 685             


Asp Trp Leu Ser Ala Glu Thr Phe Glu Ser Asp Leu Asp Glu Thr Arg 
    690                 695                 700                 


Val Pro Glu Val Pro Ser Ser Leu His Val Arg Pro Leu Val Thr Ser 
705                 710                 715                 720 


Ile Val Val Ser Trp Thr Pro Pro Glu Asn Gln Asn Ile Val Val Arg 
                725                 730                 735     


Gly Tyr Ala Ile Gly Tyr Gly Ile Gly Ser Pro His Ala Gln Thr Ile 
            740                 745                 750         


Lys Val Asp Tyr Lys Gln Arg Tyr Tyr Thr Ile Glu Asn Leu Asp Pro 
        755                 760                 765             


Ser Ser His Tyr Val Ile Thr Leu Lys Ala Phe Asn Asn Val Gly Glu 
    770                 775                 780                 


Gly Ile Pro Leu Tyr Glu Ser Ala Val Thr Arg Pro His Thr Asp Thr 
785                 790                 795                 800 


Ser Glu Val Asp Leu Phe Val Ile Asn Ala Pro Tyr Thr Pro Val Pro 
                805                 810                 815     


Asp Pro Thr Pro Met Met Pro Pro Val Gly Val Gln Ala Ser Ile Leu 
            820                 825                 830         


Ser His Asp Thr Ile Arg Ile Thr Trp Ala Asp Asn Ser Leu Pro Lys 
        835                 840                 845             


His Gln Lys Ile Thr Asp Ser Arg Tyr Tyr Thr Val Arg Trp Lys Thr 
    850                 855                 860                 


Asn Ile Pro Ala Asn Thr Lys Tyr Lys Asn Ala Asn Ala Thr Thr Leu 
865                 870                 875                 880 


Ser Tyr Leu Val Thr Gly Leu Lys Pro Asn Thr Leu Tyr Glu Phe Ser 
                885                 890                 895     


Val Met Val Thr Lys Gly Arg Arg Ser Ser Thr Trp Ser Met Thr Ala 
            900                 905                 910         


His Gly Thr Thr Phe Glu Leu Val Pro Thr Ser Pro Pro Lys Asp Val 
        915                 920                 925             


Thr Val Val Ser Lys Glu Gly Lys Pro Lys Thr Ile Ile Val Asn Trp 
    930                 935                 940                 


Gln Pro Pro Ser Glu Ala Asn Gly Lys Ile Thr Gly Tyr Ile Ile Tyr 
945                 950                 955                 960 


Tyr Ser Thr Asp Val Asn Ala Glu Ile His Asp Trp Val Ile Glu Pro 
                965                 970                 975     


Val Val Gly Asn Arg Leu Thr His Gln Ile Gln Glu Leu Thr Leu Asp 
            980                 985                 990         


Thr Pro Tyr Tyr Phe Lys Ile Gln  Ala Arg Asn Ser Lys  Gly Met Gly 
        995                 1000                 1005             


Pro Met  Ser Glu Ala Val Gln  Phe Arg Thr Pro Lys  Ala Asp Ser 
    1010                 1015                 1020             


Ser Asp  Lys Met Pro Asn Asp  Gln Ala Ser Gly Ser  Gly Gly Lys 
    1025                 1030                 1035             


Gly Ser  Arg Leu Pro Asp Leu  Gly Ser Asp Tyr Lys  Pro Pro Met 
    1040                 1045                 1050             


Ser Gly  Ser Asn Ser Pro His  Gly Ser Pro Thr Ser  Pro Leu Asp 
    1055                 1060                 1065             


Ser Asn  Met Leu 
    1070         


<210>  985
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  985

Gln Ser Val Thr His Thr Gly Leu Pro Ile Met Ala Ser Leu Ala Asn 
1               5                   10                  15      


Thr Ala Ile Ser Phe Ser Cys Arg Ile Thr Tyr Pro Tyr Thr Pro Gln 
            20                  25                  30          


Phe Lys Val Phe Thr Val Ser Tyr Phe His Glu Asp Leu Gln Gly Gln 
        35                  40                  45              


Arg Ser Pro Lys Lys Pro Thr Asn Cys His Pro Gly Leu Gly Thr Glu 
    50                  55                  60                  


Asn Gln Ser His Thr Leu Asp Cys Gln Val Thr Leu Val Leu Pro Gly 
65                  70                  75                  80  


Ala Ser Ala Thr Gly Thr Tyr Tyr Cys Ser Val His Trp Pro His Ser 
                85                  90                  95      


Thr Val Arg Gly Ser Gly Thr Phe Ile Leu Val Arg Asp Ala Gly Tyr 
            100                 105                 110         


Arg Glu Pro Pro Gln Ser Pro Gln Lys 
        115                 120     


<210>  986
<211>  1086
<212>  PRT
<213>  Homo Sapiens

<400>  986

Ile Glu Ile Pro Met Asp Pro Ser Ile Gln Asn Glu Leu Thr Gln Pro 
1               5                   10                  15      


Pro Thr Ile Thr Lys Gln Ser Ala Lys Asp His Ile Val Asp Pro Arg 
            20                  25                  30          


Asp Asn Ile Leu Ile Glu Cys Glu Ala Lys Gly Asn Pro Ala Pro Ser 
        35                  40                  45              


Phe His Trp Thr Arg Asn Ser Arg Phe Phe Asn Ile Ala Lys Asp Pro 
    50                  55                  60                  


Arg Val Ser Met Arg Arg Arg Ser Gly Thr Leu Val Ile Asp Phe Arg 
65                  70                  75                  80  


Ser Gly Gly Arg Pro Glu Glu Tyr Glu Gly Glu Tyr Gln Cys Phe Ala 
                85                  90                  95      


Arg Asn Lys Phe Gly Thr Ala Leu Ser Asn Arg Ile Arg Leu Gln Val 
            100                 105                 110         


Ser Lys Ser Pro Leu Trp Pro Lys Glu Asn Leu Asp Pro Val Val Val 
        115                 120                 125             


Gln Glu Gly Ala Pro Leu Thr Leu Gln Cys Asn Pro Pro Pro Gly Leu 
    130                 135                 140                 


Pro Ser Pro Val Ile Phe Trp Met Ser Ser Ser Met Glu Pro Ile Thr 
145                 150                 155                 160 


Gln Asp Lys Arg Val Ser Gln Gly His Asn Gly Asp Leu Tyr Phe Ser 
                165                 170                 175     


Asn Val Met Leu Gln Asp Met Gln Thr Asp Tyr Ser Cys Asn Ala Arg 
            180                 185                 190         


Phe His Phe Thr His Thr Ile Gln Gln Lys Asn Pro Phe Thr Leu Lys 
        195                 200                 205             


Val Leu Thr Thr Arg Gly Val Ala Glu Arg Thr Pro Ser Phe Met Tyr 
    210                 215                 220                 


Pro Gln Gly Thr Ala Ser Ser Gln Met Val Leu Arg Gly Met Asp Leu 
225                 230                 235                 240 


Leu Leu Glu Cys Ile Ala Ser Gly Val Pro Thr Pro Asp Ile Ala Trp 
                245                 250                 255     


Tyr Lys Lys Gly Gly Asp Leu Pro Ser Asp Lys Ala Lys Phe Glu Asn 
            260                 265                 270         


Phe Asn Lys Ala Leu Arg Ile Thr Asn Val Ser Glu Glu Asp Ser Gly 
        275                 280                 285             


Glu Tyr Phe Cys Leu Ala Ser Asn Lys Met Gly Ser Ile Arg His Thr 
    290                 295                 300                 


Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp Leu Asp Glu Pro Lys 
305                 310                 315                 320 


Asn Leu Ile Leu Ala Pro Gly Glu Asp Gly Arg Leu Val Cys Arg Ala 
                325                 330                 335     


Asn Gly Asn Pro Lys Pro Thr Val Gln Trp Met Val Asn Gly Glu Pro 
            340                 345                 350         


Leu Gln Ser Ala Pro Pro Asn Pro Asn Arg Glu Val Ala Gly Asp Thr 
        355                 360                 365             


Ile Ile Phe Arg Asp Thr Gln Ile Ser Ser Arg Ala Val Tyr Gln Cys 
    370                 375                 380                 


Asn Thr Ser Asn Glu His Gly Tyr Leu Leu Ala Asn Ala Phe Val Ser 
385                 390                 395                 400 


Val Leu Asp Val Pro Pro Arg Met Leu Ser Pro Arg Asn Gln Leu Ile 
                405                 410                 415     


Arg Val Ile Leu Tyr Asn Arg Thr Arg Leu Asp Cys Pro Phe Phe Gly 
            420                 425                 430         


Ser Pro Ile Pro Thr Leu Arg Trp Phe Lys Asn Gly Gln Gly Ser Asn 
        435                 440                 445             


Leu Asp Gly Gly Asn Tyr His Val Tyr Glu Asn Gly Ser Leu Glu Ile 
    450                 455                 460                 


Lys Met Ile Arg Lys Glu Asp Gln Gly Ile Tyr Thr Cys Val Ala Thr 
465                 470                 475                 480 


Asn Ile Leu Gly Lys Ala Glu Asn Gln Val Arg Leu Glu Val Lys Asp 
                485                 490                 495     


Pro Thr Arg Ile Tyr Arg Met Pro Glu Asp Gln Val Ala Arg Arg Gly 
            500                 505                 510         


Thr Thr Val Gln Leu Glu Cys Arg Val Lys His Asp Pro Ser Leu Lys 
        515                 520                 525             


Leu Thr Val Ser Trp Leu Lys Asp Asp Glu Pro Leu Tyr Ile Gly Asn 
    530                 535                 540                 


Arg Met Lys Lys Glu Asp Asp Ser Leu Thr Ile Phe Gly Val Ala Glu 
545                 550                 555                 560 


Arg Asp Gln Gly Ser Tyr Thr Cys Val Ala Ser Thr Glu Leu Asp Gln 
                565                 570                 575     


Asp Leu Ala Lys Ala Tyr Leu Thr Val Leu Ala Asp Gln Ala Thr Pro 
            580                 585                 590         


Thr Asn Arg Leu Ala Ala Leu Pro Lys Gly Arg Pro Asp Arg Pro Arg 
        595                 600                 605             


Asp Leu Glu Leu Thr Asp Leu Ala Glu Arg Ser Val Arg Leu Thr Trp 
    610                 615                 620                 


Ile Pro Gly Asp Ala Asn Asn Ser Pro Ile Thr Asp Tyr Val Val Gln 
625                 630                 635                 640 


Phe Glu Glu Asp Gln Phe Gln Pro Gly Val Trp His Asp His Ser Lys 
                645                 650                 655     


Tyr Pro Gly Ser Val Asn Ser Ala Val Leu Arg Leu Ser Pro Tyr Val 
            660                 665                 670         


Asn Tyr Gln Phe Arg Val Ile Ala Ile Asn Glu Val Gly Ser Ser His 
        675                 680                 685             


Pro Ser Leu Pro Ser Glu Arg Tyr Arg Thr Ser Gly Ala Pro Pro Glu 
    690                 695                 700                 


Ser Asn Pro Gly Asp Val Lys Gly Glu Gly Thr Arg Lys Asn Asn Met 
705                 710                 715                 720 


Glu Ile Thr Trp Thr Pro Met Asn Ala Thr Ser Ala Phe Gly Pro Asn 
                725                 730                 735     


Leu Arg Tyr Ile Val Lys Trp Arg Arg Arg Glu Thr Arg Glu Ala Trp 
            740                 745                 750         


Asn Asn Val Thr Val Trp Gly Ser Arg Tyr Val Val Gly Gln Thr Pro 
        755                 760                 765             


Val Tyr Val Pro Tyr Glu Ile Arg Val Gln Ala Glu Asn Asp Phe Gly 
    770                 775                 780                 


Lys Gly Pro Glu Pro Glu Ser Val Ile Gly Tyr Ser Gly Glu Asp Leu 
785                 790                 795                 800 


Pro Ser Ala Pro Arg Arg Phe Arg Val Arg Gln Pro Asn Leu Glu Thr 
                805                 810                 815     


Ile Asn Leu Glu Trp Asp His Pro Glu His Pro Asn Gly Ile Met Ile 
            820                 825                 830         


Gly Tyr Thr Leu Lys Tyr Val Ala Phe Asn Gly Thr Lys Val Gly Lys 
        835                 840                 845             


Gln Ile Val Glu Asn Phe Ser Pro Asn Gln Thr Lys Phe Thr Val Gln 
    850                 855                 860                 


Arg Thr Asp Pro Val Ser Arg Tyr Arg Phe Thr Leu Ser Ala Arg Thr 
865                 870                 875                 880 


Gln Val Gly Ser Gly Glu Ala Val Thr Glu Glu Ser Pro Ala Pro Pro 
                885                 890                 895     


Asn Glu Ala Thr Pro Thr Ala Ala Pro Pro Thr Leu Pro Pro Thr Thr 
            900                 905                 910         


Val Gly Ala Thr Gly Ala Val Ser Ser Thr Asp Ala Thr Ala Ile Ala 
        915                 920                 925             


Ala Thr Thr Glu Ala Thr Thr Val Pro Ile Ile Pro Thr Val Ala Pro 
    930                 935                 940                 


Thr Thr Ile Ala Thr Thr Thr Thr Val Ala Thr Thr Thr Thr Thr Thr 
945                 950                 955                 960 


Ala Ala Ala Thr Thr Thr Thr Glu Ser Pro Pro Thr Thr Thr Ser Gly 
                965                 970                 975     


Thr Lys Ile His Glu Ser Ala Pro Asp Glu Gln Ser Ile Trp Asn Val 
            980                 985                 990         


Thr Val Leu Pro Asn Ser Lys Trp  Ala Asn Ile Thr Trp  Lys His Asn 
        995                 1000                 1005             


Phe Gly  Pro Gly Thr Asp Phe  Val Val Glu Tyr Ile  Asp Ser Asn 
    1010                 1015                 1020             


His Thr  Lys Lys Thr Val Pro  Val Lys Ala Gln Ala  Gln Pro Ile 
    1025                 1030                 1035             


Gln Leu  Thr Asp Leu Tyr Pro  Gly Met Thr Tyr Thr  Leu Arg Val 
    1040                 1045                 1050             


Tyr Ser  Arg Asp Asn Glu Gly  Ile Ser Ser Thr Val  Ile Thr Phe 
    1055                 1060                 1065             


Met Thr  Ser Thr Ala Tyr Thr  Asn Asn Gln Ala Asp  Ile Ala Thr 
    1070                 1075                 1080             


Gln Gly  Trp 
    1085     


<210>  987
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  987

Ser Ser Ser His Pro Ile Phe His Arg Gly Glu Phe Ser Val Cys Asp 
1               5                   10                  15      


Ser Val Ser Val Trp Val Gly Asp Lys Thr Thr Ala Thr Asp Ile Lys 
            20                  25                  30          


Gly Lys Glu Val Met Val Leu Gly Glu Val Asn Ile Asn Asn Ser Val 
        35                  40                  45              


Phe Lys Gln Tyr Phe Phe Glu Thr Lys Cys Arg Asp Pro Asn Pro Val 
    50                  55                  60                  


Asp Ser Gly Cys Arg Gly Ile Asp Ser Lys His Trp Asn Ser Tyr Cys 
65                  70                  75                  80  


Thr Thr Thr His Thr Phe Val Lys Ala Leu Thr Met Asp Gly Lys Gln 
                85                  90                  95      


Ala Ala Trp Arg Phe Ile Arg Ile Asp Thr Ala Cys Val Cys Val Leu 
            100                 105                 110         


Ser Arg Lys Ala Val Arg Arg Ala 
        115                 120 


<210>  988
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  988

Lys Glu Ala Cys Pro Thr Gly Leu Tyr Thr His Ser Gly Glu Cys Cys 
1               5                   10                  15      


Lys Ala Cys Asn Leu Gly Glu Gly Val Ala Gln Pro Cys Gly Ala Asn 
            20                  25                  30          


Gln Thr Val Cys Glu Pro Cys Leu Asp Ser Val Thr Phe Ser Asp Val 
        35                  40                  45              


Val Ser Ala Thr Glu Pro Cys Lys Pro Cys Thr Glu Cys Val Gly Leu 
    50                  55                  60                  


Gln Ser Met Ser Ala Pro Cys Val Glu Ala Asp Asp Ala Val Cys Arg 
65                  70                  75                  80  


Cys Ala Tyr Gly Tyr Tyr Gln Asp Glu Thr Thr Gly Arg Cys Glu Ala 
                85                  90                  95      


Cys Arg Val Cys Glu Ala Gly Ser Gly Leu Val Phe Ser Cys Gln Asp 
            100                 105                 110         


Lys Gln Asn Thr Val Cys Glu Glu Cys Pro Asp Gly Thr Tyr Ser Asp 
        115                 120                 125             


Glu Ala Asn His Val Asp Pro Cys Leu Pro Cys Thr Val Cys Glu Asp 
    130                 135                 140                 


Thr Glu Arg Gln Leu Arg Glu Cys Thr Arg Trp Ala Asp Ala Glu Cys 
145                 150                 155                 160 


Glu Glu Ile Pro Gly Arg Trp Ile Thr Arg Ser Thr Pro Pro Glu Gly 
                165                 170                 175     


Ser Asp Ser Thr Ala Pro Ser Thr Gln Glu Pro Glu Ala Pro Pro Glu 
            180                 185                 190         


Gln Asp Leu Ile Ala Ser Thr Val Ala Gly Val Val Thr Thr Val Met 
        195                 200                 205             


Gly Ser Ser Gln Pro Val Val Thr Arg Gly Thr Thr Asp Asn 
    210                 215                 220         


<210>  989
<211>  729
<212>  PRT
<213>  Homo Sapiens

<400>  989

Ser Arg Gln Thr Cys Ala Asn Asn Arg His Gln Cys Ser Val His Ala 
1               5                   10                  15      


Glu Cys Arg Asp Tyr Ala Thr Gly Phe Cys Cys Ser Cys Val Ala Gly 
            20                  25                  30          


Tyr Thr Gly Asn Gly Arg Gln Cys Val Ala Glu Gly Ser Pro Gln Arg 
        35                  40                  45              


Val Asn Gly Lys Val Lys Gly Arg Ile Phe Val Gly Ser Ser Gln Val 
    50                  55                  60                  


Pro Ile Val Phe Glu Asn Thr Asp Leu His Ser Tyr Val Val Met Asn 
65                  70                  75                  80  


His Gly Arg Ser Tyr Thr Ala Ile Ser Thr Ile Pro Glu Thr Val Gly 
                85                  90                  95      


Tyr Ser Leu Leu Pro Leu Ala Pro Val Gly Gly Ile Ile Gly Trp Met 
            100                 105                 110         


Phe Ala Val Glu Gln Asp Gly Phe Lys Asn Gly Phe Ser Ile Thr Gly 
        115                 120                 125             


Gly Glu Phe Thr Arg Gln Ala Glu Val Thr Phe Val Gly His Pro Gly 
    130                 135                 140                 


Asn Leu Val Ile Lys Gln Arg Phe Ser Gly Ile Asp Glu His Gly His 
145                 150                 155                 160 


Leu Thr Ile Asp Thr Glu Leu Glu Gly Arg Val Pro Gln Ile Pro Phe 
                165                 170                 175     


Gly Ser Ser Val His Ile Glu Pro Tyr Thr Glu Leu Tyr His Tyr Ser 
            180                 185                 190         


Thr Ser Val Ile Thr Ser Ser Ser Thr Arg Glu Tyr Thr Val Thr Glu 
        195                 200                 205             


Pro Glu Arg Asp Gly Ala Ser Pro Ser Arg Ile Tyr Thr Tyr Gln Trp 
    210                 215                 220                 


Arg Gln Thr Ile Thr Phe Gln Glu Cys Val His Asp Asp Ser Arg Pro 
225                 230                 235                 240 


Ala Leu Pro Ser Thr Gln Gln Leu Ser Val Asp Ser Val Phe Val Leu 
                245                 250                 255     


Tyr Asn Gln Glu Glu Lys Ile Leu Arg Tyr Ala Leu Ser Asn Ser Ile 
            260                 265                 270         


Gly Pro Val Arg Glu Gly Ser Pro Asp Ala Leu Gln Asn Pro Cys Tyr 
        275                 280                 285             


Ile Gly Thr His Gly Cys Asp Thr Asn Ala Ala Cys Arg Pro Gly Pro 
    290                 295                 300                 


Arg Thr Gln Phe Thr Cys Glu Cys Ser Ile Gly Phe Arg Gly Asp Gly 
305                 310                 315                 320 


Arg Thr Cys Tyr Glu Val Glu Lys Thr Arg Cys Gln His Glu Arg Glu 
                325                 330                 335     


His Ile Leu Gly Ala Ala Gly Ala Thr Asp Pro Gln Arg Pro Ile Pro 
            340                 345                 350         


Pro Gly Leu Phe Val Pro Glu Cys Asp Ala His Gly His Tyr Ala Pro 
        355                 360                 365             


Thr Gln Cys His Gly Ser Thr Gly Tyr Cys Trp Cys Val Asp Arg Asp 
    370                 375                 380                 


Gly Arg Glu Val Glu Gly Thr Arg Thr Arg Pro Gly Met Thr Pro Pro 
385                 390                 395                 400 


Cys Leu Ser Thr Val Ala Pro Pro Ile His Gln Gly Pro Ala Val Pro 
                405                 410                 415     


Thr Ala Val Ile Pro Leu Pro Pro Gly Thr His Leu Leu Phe Ala Gln 
            420                 425                 430         


Thr Gly Lys Ile Glu Arg Leu Pro Leu Glu Gly Asn Thr Met Arg Lys 
        435                 440                 445             


Thr Glu Ala Lys Ala Phe Leu His Val Pro Ala Lys Val Ile Ile Gly 
    450                 455                 460                 


Leu Ala Phe Asp Cys Val Asp Lys Met Val Tyr Trp Thr Asp Ile Thr 
465                 470                 475                 480 


Glu Pro Ser Ile Gly Arg Ala Ser Leu His Gly Gly Glu Pro Thr Thr 
                485                 490                 495     


Ile Ile Arg Gln Asp Leu Gly Ser Pro Glu Gly Ile Ala Val Asp His 
            500                 505                 510         


Leu Gly Arg Asn Ile Phe Trp Thr Asp Ser Asn Leu Asp Arg Ile Glu 
        515                 520                 525             


Val Ala Lys Leu Asp Gly Thr Gln Arg Arg Val Leu Phe Glu Thr Asp 
    530                 535                 540                 


Leu Val Asn Pro Arg Gly Ile Val Thr Asp Ser Val Arg Gly Asn Leu 
545                 550                 555                 560 


Tyr Trp Thr Asp Trp Asn Arg Asp Asn Pro Lys Ile Glu Thr Ser Tyr 
                565                 570                 575     


Met Asp Gly Thr Asn Arg Arg Ile Leu Val Gln Asp Asp Leu Gly Leu 
            580                 585                 590         


Pro Asn Gly Leu Thr Phe Asp Ala Phe Ser Ser Gln Leu Cys Trp Val 
        595                 600                 605             


Asp Ala Gly Thr Asn Arg Ala Glu Cys Leu Asn Pro Ser Gln Pro Ser 
    610                 615                 620                 


Arg Arg Lys Ala Leu Glu Gly Leu Gln Tyr Pro Phe Ala Val Thr Ser 
625                 630                 635                 640 


Tyr Gly Lys Asn Leu Tyr Phe Thr Asp Trp Lys Met Asn Ser Val Val 
                645                 650                 655     


Ala Leu Asp Leu Ala Ile Ser Lys Glu Thr Asp Ala Phe Gln Pro His 
            660                 665                 670         


Lys Gln Thr Arg Leu Tyr Gly Ile Thr Thr Ala Leu Ser Gln Cys Pro 
        675                 680                 685             


Gln Gly His Asn Tyr Cys Ser Val Asn Asn Gly Gly Cys Thr His Leu 
    690                 695                 700                 


Cys Leu Ala Thr Pro Gly Ser Arg Thr Cys Arg Cys Pro Asp Asn Thr 
705                 710                 715                 720 


Leu Gly Val Asp Cys Ile Glu Gln Lys 
                725                 


<210>  990
<211>  939
<212>  PRT
<213>  Homo Sapiens

<400>  990

Leu His Pro Asp Glu Leu Phe Pro His Gly Glu Ser Trp Gly Asp Gln 
1               5                   10                  15      


Leu Leu Gln Glu Gly Asp Asp Glu Ser Ser Ala Val Val Lys Leu Ala 
            20                  25                  30          


Asn Pro Leu His Phe Tyr Glu Ala Arg Phe Ser Asn Leu Tyr Val Gly 
        35                  40                  45              


Thr Asn Gly Ile Ile Ser Thr Gln Asp Phe Pro Arg Glu Thr Gln Tyr 
    50                  55                  60                  


Val Asp Tyr Asp Phe Pro Thr Asp Phe Pro Ala Ile Ala Pro Phe Leu 
65                  70                  75                  80  


Ala Asp Ile Asp Thr Ser His Gly Arg Gly Arg Val Leu Tyr Arg Val 
                85                  90                  95      


Asn Gly Lys Val Ser Gly His Leu His Val Gly His Thr Pro Val His 
            100                 105                 110         


Phe Thr Asp Val Asp Leu His Ala Tyr Ile Val Gly Asn Asp Gly Arg 
        115                 120                 125             


Ala Tyr Thr Ala Ile Ser His Ile Pro Gln Pro Ala Ala Gln Ala Leu 
    130                 135                 140                 


Leu Pro Leu Thr Pro Ile Gly Gly Leu Phe Gly Trp Leu Phe Ala Leu 
145                 150                 155                 160 


Glu Lys Pro Gly Ser Glu Asn Gly Phe Ser Leu Ala Gly Ala Ala Phe 
                165                 170                 175     


Thr His Asp Met Glu Val Thr Phe Tyr Pro Gly Glu Glu Thr Val Arg 
            180                 185                 190         


Ile Thr Gln Thr Ala Glu Gly Leu Asp Pro Glu Asn Tyr Leu Ser Ile 
        195                 200                 205             


Lys Thr Asn Ile Gln Gly Gln Val Pro Tyr Val Pro Ala Asn Phe Thr 
    210                 215                 220                 


Ala His Ile Ser Pro Tyr Lys Glu Leu Tyr His Tyr Ser Asp Ser Thr 
225                 230                 235                 240 


Val Thr Ser Thr Ser Ser Arg Asp Tyr Ser Leu Thr Phe Gly Ala Ile 
                245                 250                 255     


Asn Gln Thr Trp Ser Tyr Arg Ile His Gln Asn Ile Thr Tyr Gln Val 
            260                 265                 270         


Cys Arg His Ala Pro Arg His Pro Ser Phe Pro Thr Thr Gln Gln Leu 
        275                 280                 285             


Asn Val Asp Arg Val Phe Ala Leu Tyr Asn Asp Glu Glu Arg Val Leu 
    290                 295                 300                 


Arg Phe Ala Val Thr Asn Gln Ile Gly Pro Val Lys Glu Asp Ser Asp 
305                 310                 315                 320 


Pro Thr Pro Val Asn Pro Cys Tyr Asp Gly Ser His Met Cys Asp Thr 
                325                 330                 335     


Thr Ala Arg Cys His Pro Gly Thr Gly Val Asp Tyr Thr Cys Glu Cys 
            340                 345                 350         


Ala Ser Gly Tyr Gln Gly Asp Gly Arg Asn Cys Val Asp Glu Asn Glu 
        355                 360                 365             


Cys Ala Thr Gly Phe His Arg Cys Gly Pro Asn Ser Val Cys Ile Asn 
    370                 375                 380                 


Leu Pro Gly Ser Tyr Arg Cys Glu Cys Arg Ser Ala Tyr Glu Phe Ala 
385                 390                 395                 400 


Asp Asp Arg His Thr Cys Ile Leu Ile Thr Pro Pro Ala Asn Pro Cys 
                405                 410                 415     


Glu Asp Gly Ser His Thr Cys Ala Pro Ala Gly Gln Ala Arg Cys Val 
            420                 425                 430         


His His Gly Gly Ser Thr Phe Ser Cys Ala Cys Leu Pro Gly Tyr Ala 
        435                 440                 445             


Gly Asp Gly His Gln Cys Thr Asp Val Asp Glu Cys Ser Glu Asn Arg 
    450                 455                 460                 


Cys His Pro Ala Ala Thr Cys Tyr Asn Thr Pro Gly Ser Phe Ser Cys 
465                 470                 475                 480 


Arg Cys Gln Pro Gly Tyr Tyr Gly Asp Gly Phe Gln Cys Ile Pro Asp 
                485                 490                 495     


Ser Thr Ser Ser Leu Thr Pro Cys Glu Gln Gln Gln Arg His Ala Gln 
            500                 505                 510         


Ala Gln Tyr Ala Tyr Pro Gly Ala Arg Phe His Ile Pro Gln Cys Asp 
        515                 520                 525             


Glu Gln Gly Asn Phe Leu Pro Leu Gln Cys His Gly Ser Thr Gly Phe 
    530                 535                 540                 


Cys Trp Cys Val Asp Pro Asp Gly His Glu Val Pro Gly Thr Gln Thr 
545                 550                 555                 560 


Pro Pro Gly Ser Thr Pro Pro His Cys Gly Pro Ser Pro Glu Pro Thr 
                565                 570                 575     


Gln Arg Pro Pro Thr Ile Cys Glu Arg Trp Arg Glu Asn Leu Leu Glu 
            580                 585                 590         


His Tyr Gly Gly Thr Pro Arg Asp Asp Gln Tyr Val Pro Gln Cys Asp 
        595                 600                 605             


Asp Leu Gly His Phe Ile Pro Leu Gln Cys His Gly Lys Ser Asp Phe 
    610                 615                 620                 


Cys Trp Cys Val Asp Lys Asp Gly Arg Glu Val Gln Gly Thr Arg Ser 
625                 630                 635                 640 


Gln Pro Gly Thr Thr Pro Ala Cys Ile Pro Thr Val Ala Pro Pro Met 
                645                 650                 655     


Val Arg Pro Thr Pro Arg Pro Asp Val Thr Pro Pro Ser Val Gly Thr 
            660                 665                 670         


Phe Leu Leu Tyr Thr Gln Gly Gln Gln Ile Gly Tyr Leu Pro Leu Asn 
        675                 680                 685             


Gly Thr Arg Leu Gln Lys Asp Ala Ala Lys Thr Leu Leu Ser Leu His 
    690                 695                 700                 


Gly Ser Ile Ile Val Gly Ile Asp Tyr Asp Cys Arg Glu Arg Met Val 
705                 710                 715                 720 


Tyr Trp Thr Asp Val Ala Gly Arg Thr Ile Ser Arg Ala Gly Leu Glu 
                725                 730                 735     


Leu Gly Ala Glu Pro Glu Thr Ile Val Asn Ser Gly Leu Ile Ser Pro 
            740                 745                 750         


Glu Gly Leu Ala Ile Asp His Ile Arg Arg Thr Met Tyr Trp Thr Asp 
        755                 760                 765             


Ser Val Leu Asp Lys Ile Glu Ser Ala Leu Leu Asp Gly Ser Glu Arg 
    770                 775                 780                 


Lys Val Leu Phe Tyr Thr Asp Leu Val Asn Pro Arg Ala Ile Ala Val 
785                 790                 795                 800 


Asp Pro Ile Arg Gly Asn Leu Tyr Trp Thr Asp Trp Asn Arg Glu Ala 
                805                 810                 815     


Pro Lys Ile Glu Thr Ser Ser Leu Asp Gly Glu Asn Arg Arg Ile Leu 
            820                 825                 830         


Ile Asn Thr Asp Ile Gly Leu Pro Asn Gly Leu Thr Phe Asp Pro Phe 
        835                 840                 845             


Ser Lys Leu Leu Cys Trp Ala Asp Ala Gly Thr Lys Lys Leu Glu Cys 
    850                 855                 860                 


Thr Leu Pro Asp Gly Thr Gly Arg Arg Val Ile Gln Asn Asn Leu Lys 
865                 870                 875                 880 


Tyr Pro Phe Ser Ile Val Ser Tyr Ala Asp His Phe Tyr His Thr Asp 
                885                 890                 895     


Trp Arg Arg Asp Gly Val Val Ser Val Asn Lys His Ser Gly Gln Phe 
            900                 905                 910         


Thr Asp Glu Tyr Leu Pro Glu Gln Arg Ser His Leu Tyr Gly Ile Thr 
        915                 920                 925             


Ala Val Tyr Pro Tyr Cys Pro Thr Gly Arg Lys 
    930                 935                 


<210>  991
<211>  633
<212>  PRT
<213>  Homo Sapiens

<400>  991

Gln Tyr Pro Val Val Asn Thr Asn Tyr Gly Lys Ile Gln Gly Leu Arg 
1               5                   10                  15      


Thr Pro Leu Pro Ser Glu Ile Leu Gly Pro Val Glu Gln Tyr Leu Gly 
            20                  25                  30          


Val Pro Tyr Ala Ser Pro Pro Thr Gly Glu Arg Arg Phe Gln Pro Pro 
        35                  40                  45              


Glu Ser Pro Ser Ser Trp Thr Gly Ile Arg Asn Ala Thr Gln Phe Ser 
    50                  55                  60                  


Ala Val Cys Pro Gln His Leu Asp Glu Arg Phe Leu Leu His Asp Met 
65                  70                  75                  80  


Leu Pro Ile Trp Phe Thr Thr Ser Leu Asp Thr Leu Met Thr Tyr Val 
                85                  90                  95      


Gln Asp Gln Asn Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Val Pro Met 
            100                 105                 110         


Glu Asp Asp Ile His Glu Gln Asn Ser Lys Lys Pro Val Met Val Tyr 
        115                 120                 125             


Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly Asn Met Ile Asp Gly 
    130                 135                 140                 


Ser Ile Leu Ala Ser Tyr Gly Asn Val Ile Val Ile Thr Ile Asn Tyr 
145                 150                 155                 160 


Arg Leu Gly Ile Leu Gly Phe Leu Ser Thr Gly Asp Gln Ala Ala Lys 
                165                 170                 175     


Gly Asn Tyr Gly Leu Leu Asp Gln Ile Gln Ala Leu Arg Trp Ile Glu 
            180                 185                 190         


Glu Asn Val Gly Ala Phe Gly Gly Asp Pro Lys Arg Val Thr Ile Phe 
        195                 200                 205             


Gly Ser Gly Ala Gly Ala Ser Cys Val Ser Leu Leu Thr Leu Ser His 
    210                 215                 220                 


Tyr Ser Glu Gly Leu Phe Gln Lys Ala Ile Ile Gln Ser Gly Thr Ala 
225                 230                 235                 240 


Leu Ser Ser Trp Ala Val Asn Tyr Gln Pro Ala Lys Tyr Thr Arg Ile 
                245                 250                 255     


Leu Ala Asp Lys Val Gly Cys Asn Met Leu Asp Thr Thr Asp Met Val 
            260                 265                 270         


Glu Cys Leu Lys Asn Lys Asn Tyr Lys Glu Leu Ile Gln Gln Thr Ile 
        275                 280                 285             


Thr Pro Ala Thr Tyr His Ile Ala Phe Gly Pro Val Ile Asp Gly Asp 
    290                 295                 300                 


Val Ile Pro Asp Asp Pro Gln Ile Leu Met Glu Gln Gly Glu Phe Leu 
305                 310                 315                 320 


Asn Tyr Asp Ile Met Leu Gly Val Asn Gln Gly Glu Gly Leu Lys Phe 
                325                 330                 335     


Val Asp Gly Ile Val Asp Asn Glu Asp Gly Val Thr Pro Asn Asp Phe 
            340                 345                 350         


Asp Phe Ser Val Ser Asn Phe Val Asp Asn Leu Tyr Gly Tyr Pro Glu 
        355                 360                 365             


Gly Lys Asp Thr Leu Arg Glu Thr Ile Lys Phe Met Tyr Thr Asp Trp 
    370                 375                 380                 


Ala Asp Lys Glu Asn Pro Glu Thr Arg Arg Lys Thr Leu Val Ala Leu 
385                 390                 395                 400 


Phe Thr Asp His Gln Trp Val Ala Pro Ala Val Ala Thr Ala Asp Leu 
                405                 410                 415     


His Ala Gln Tyr Gly Ser Pro Thr Tyr Phe Tyr Ala Phe Tyr His His 
            420                 425                 430         


Cys Gln Ser Glu Met Lys Pro Ser Trp Ala Asp Ser Ala His Gly Asp 
        435                 440                 445             


Glu Val Pro Tyr Val Phe Gly Ile Pro Met Ile Gly Pro Thr Glu Leu 
    450                 455                 460                 


Phe Ser Cys Asn Phe Ser Lys Asn Asp Val Met Leu Ser Ala Val Val 
465                 470                 475                 480 


Met Thr Tyr Trp Thr Asn Phe Ala Lys Thr Gly Asp Pro Asn Gln Pro 
                485                 490                 495     


Val Pro Gln Asp Thr Lys Phe Ile His Thr Lys Pro Asn Arg Phe Glu 
            500                 505                 510         


Glu Val Ala Trp Ser Lys Tyr Asn Pro Lys Asp Gln Leu Tyr Leu His 
        515                 520                 525             


Ile Gly Leu Lys Pro Arg Val Arg Asp His Tyr Arg Ala Thr Lys Val 
    530                 535                 540                 


Ala Phe Trp Leu Glu Leu Val Pro His Leu His Asn Leu Asn Glu Ile 
545                 550                 555                 560 


Phe Gln Tyr Val Ser Thr Thr Thr Lys Val Pro Pro Pro Asp Met Thr 
                565                 570                 575     


Ser Phe Pro Tyr Gly Thr Arg Arg Ser Pro Ala Lys Ile Trp Pro Thr 
            580                 585                 590         


Thr Lys Arg Pro Ala Ile Thr Pro Ala Asn Asn Pro Lys His Ser Lys 
        595                 600                 605             


Asp Pro His Lys Thr Gly Pro Glu Asp Thr Thr Val Leu Ile Glu Thr 
    610                 615                 620                 


Lys Arg Asp Tyr Ser Thr Glu Leu Ser 
625                 630             


<210>  992
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  992

Gln Tyr Pro Val Val Asn Thr Asn Tyr Gly Lys Ile Gln Gly Leu Arg 
1               5                   10                  15      


Thr Pro Leu Pro Ser Glu Ile Leu Gly Pro Val Glu Gln Tyr Leu Gly 
            20                  25                  30          


Val Pro Tyr Ala Ser Pro Pro Thr Gly Glu Arg Arg Phe Gln Pro Pro 
        35                  40                  45              


Glu Ser Pro Ser Ser Trp Thr Gly Ile Arg Asn Ala Thr Gln Phe Ser 
    50                  55                  60                  


Ala Val Cys Pro Gln His Leu Asp Glu Arg Phe Leu Leu His Asp Met 
65                  70                  75                  80  


Leu Pro Ile Trp Phe Thr Thr Ser Leu Asp Thr Leu Met Thr Tyr Val 
                85                  90                  95      


Gln Asp Gln Asn Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Val Pro Met 
            100                 105                 110         


Glu Asp Gly Thr Asn Ile Lys Arg Asn Ala Asp Asp Ile Thr Ser Asn 
        115                 120                 125             


Asp His Gly Glu Asp Lys Asp Ile His Glu Gln Asn Ser Lys Lys Pro 
    130                 135                 140                 


Val Met Val Tyr Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly Asn 
145                 150                 155                 160 


Met Ile Asp Gly Ser Ile Leu Ala Ser Tyr Gly Asn Val Ile Val Ile 
                165                 170                 175     


Thr Ile Asn Tyr Arg Leu Gly Ile Leu Gly Met Gln Glu Ala Arg Leu 
            180                 185                 190         


Cys Gly Ser Ser Lys Met Phe Asn Tyr Phe Lys Ser Pro Phe Thr Asn 
        195                 200                 205             


Leu Ile Asn Phe Phe 
    210             


<210>  993
<211>  979
<212>  PRT
<213>  Homo Sapiens

<400>  993

Met Lys Met Ala Ser Thr Arg Cys Lys Leu Ala Arg Tyr Leu Glu Asp 
1               5                   10                  15      


Leu Glu Asp Val Asp Leu Lys Lys Phe Lys Met His Leu Glu Asp Tyr 
            20                  25                  30          


Pro Pro Gln Lys Gly Cys Ile Pro Leu Pro Arg Gly Gln Thr Glu Lys 
        35                  40                  45              


Ala Asp His Val Asp Leu Ala Thr Leu Met Ile Asp Phe Asn Gly Glu 
    50                  55                  60                  


Glu Lys Ala Trp Ala Met Ala Val Trp Ile Phe Ala Ala Ile Asn Arg 
65                  70                  75                  80  


Arg Asp Leu Tyr Glu Lys Ala Lys Arg Asp Glu Pro Lys Trp Gly Ser 
                85                  90                  95      


Asp Asn Ala Arg Val Ser Asn Pro Thr Val Ile Cys Gln Glu Asp Ser 
            100                 105                 110         


Ile Glu Glu Glu Trp Met Gly Leu Leu Glu Tyr Leu Ser Arg Ile Ser 
        115                 120                 125             


Ile Cys Lys Met Lys Lys Asp Tyr Arg Lys Lys Tyr Arg Lys Tyr Val 
    130                 135                 140                 


Arg Ser Arg Phe Gln Cys Ile Glu Asp Arg Asn Ala Arg Leu Gly Glu 
145                 150                 155                 160 


Ser Val Ser Leu Asn Lys Arg Tyr Thr Arg Leu Arg Leu Ile Lys Glu 
                165                 170                 175     


His Arg Ser Gln Gln Glu Arg Glu Gln Glu Leu Leu Ala Ile Gly Lys 
            180                 185                 190         


Thr Lys Thr Cys Glu Ser Pro Val Ser Pro Ile Lys Met Glu Leu Leu 
        195                 200                 205             


Phe Asp Pro Asp Asp Glu His Ser Glu Pro Val His Thr Val Val Phe 
    210                 215                 220                 


Gln Gly Ala Ala Gly Ile Gly Lys Thr Ile Leu Ala Arg Lys Met Met 
225                 230                 235                 240 


Leu Asp Trp Ala Ser Gly Thr Leu Tyr Gln Asp Arg Phe Asp Tyr Leu 
                245                 250                 255     


Phe Tyr Ile His Cys Arg Glu Val Ser Leu Val Thr Gln Arg Ser Leu 
            260                 265                 270         


Gly Asp Leu Ile Met Ser Cys Cys Pro Asp Pro Asn Pro Pro Ile His 
        275                 280                 285             


Lys Ile Val Arg Lys Pro Ser Arg Ile Leu Phe Leu Met Asp Gly Phe 
    290                 295                 300                 


Asp Glu Leu Gln Gly Ala Phe Asp Glu His Ile Gly Pro Leu Cys Thr 
305                 310                 315                 320 


Asp Trp Gln Lys Ala Glu Arg Gly Asp Ile Leu Leu Ser Ser Leu Ile 
                325                 330                 335     


Arg Lys Lys Leu Leu Pro Glu Ala Ser Leu Leu Ile Thr Thr Arg Pro 
            340                 345                 350         


Val Ala Leu Glu Lys Leu Gln His Leu Leu Asp His Pro Arg His Val 
        355                 360                 365             


Glu Ile Leu Gly Phe Ser Glu Ala Lys Arg Lys Glu Tyr Phe Phe Lys 
    370                 375                 380                 


Tyr Phe Ser Asp Glu Ala Gln Ala Arg Ala Ala Phe Ser Leu Ile Gln 
385                 390                 395                 400 


Glu Asn Glu Val Leu Phe Thr Met Cys Phe Ile Pro Leu Val Cys Trp 
                405                 410                 415     


Ile Val Cys Thr Gly Leu Lys Gln Gln Met Glu Ser Gly Lys Ser Leu 
            420                 425                 430         


Ala Gln Thr Ser Lys Thr Thr Thr Ala Val Tyr Val Phe Phe Leu Ser 
        435                 440                 445             


Ser Leu Leu Gln Pro Arg Gly Gly Ser Gln Glu His Gly Leu Cys Ala 
    450                 455                 460                 


His Leu Trp Gly Leu Cys Ser Leu Ala Ala Asp Gly Ile Trp Asn Gln 
465                 470                 475                 480 


Lys Ile Leu Phe Glu Glu Ser Asp Leu Arg Asn His Gly Leu Gln Lys 
                485                 490                 495     


Ala Asp Val Ser Ala Phe Leu Arg Met Asn Leu Phe Gln Lys Glu Val 
            500                 505                 510         


Asp Cys Glu Lys Phe Tyr Ser Phe Ile His Met Thr Phe Gln Glu Phe 
        515                 520                 525             


Phe Ala Ala Met Tyr Tyr Leu Leu Glu Glu Glu Lys Glu Gly Arg Thr 
    530                 535                 540                 


Asn Val Pro Gly Ser Arg Leu Lys Leu Pro Ser Arg Asp Val Thr Val 
545                 550                 555                 560 


Leu Leu Glu Asn Tyr Gly Lys Phe Glu Lys Gly Tyr Leu Ile Phe Val 
                565                 570                 575     


Val Arg Phe Leu Phe Gly Leu Val Asn Gln Glu Arg Thr Ser Tyr Leu 
            580                 585                 590         


Glu Lys Lys Leu Ser Cys Lys Ile Ser Gln Gln Ile Arg Leu Glu Leu 
        595                 600                 605             


Leu Lys Trp Ile Glu Val Lys Ala Lys Ala Lys Lys Leu Gln Ile Gln 
    610                 615                 620                 


Pro Ser Gln Leu Glu Leu Phe Tyr Cys Leu Tyr Glu Met Gln Glu Glu 
625                 630                 635                 640 


Asp Phe Val Gln Arg Ala Met Asp Tyr Phe Pro Lys Ile Glu Ile Asn 
                645                 650                 655     


Leu Ser Thr Arg Met Asp His Met Val Ser Ser Phe Cys Ile Glu Asn 
            660                 665                 670         


Cys His Arg Val Glu Ser Leu Ser Leu Gly Phe Leu His Asn Met Pro 
        675                 680                 685             


Lys Glu Glu Glu Glu Glu Glu Lys Glu Gly Arg His Leu Asp Met Val 
    690                 695                 700                 


Gln Cys Val Leu Pro Ser Ser Ser His Ala Ala Cys Ser His Gly Leu 
705                 710                 715                 720 


Gly Arg Cys Gly Leu Ser His Glu Cys Cys Phe Asp Ile Ser Leu Val 
                725                 730                 735     


Leu Ser Ser Asn Gln Lys Leu Val Glu Leu Asp Leu Ser Asp Asn Ala 
            740                 745                 750         


Leu Gly Asp Phe Gly Ile Arg Leu Leu Cys Val Gly Leu Lys His Leu 
        755                 760                 765             


Leu Cys Asn Leu Lys Lys Leu Trp Leu Val Ser Cys Cys Leu Thr Ser 
    770                 775                 780                 


Ala Cys Cys Gln Asp Leu Ala Ser Val Leu Ser Thr Ser His Ser Leu 
785                 790                 795                 800 


Thr Arg Leu Tyr Val Gly Glu Asn Ala Leu Gly Asp Ser Gly Val Ala 
                805                 810                 815     


Ile Leu Cys Glu Lys Ala Lys Asn Pro Gln Cys Asn Leu Gln Lys Leu 
            820                 825                 830         


Gly Leu Val Asn Ser Gly Leu Thr Ser Val Cys Cys Ser Ala Leu Ser 
        835                 840                 845             


Ser Val Leu Ser Thr Asn Gln Asn Leu Thr His Leu Tyr Leu Arg Gly 
    850                 855                 860                 


Asn Thr Leu Gly Asp Lys Gly Ile Lys Leu Leu Cys Glu Gly Leu Leu 
865                 870                 875                 880 


His Pro Asp Cys Lys Leu Gln Val Leu Glu Leu Asp Asn Cys Asn Leu 
                885                 890                 895     


Thr Ser His Cys Cys Trp Asp Leu Ser Thr Leu Leu Thr Ser Ser Gln 
            900                 905                 910         


Ser Leu Arg Lys Leu Ser Leu Gly Asn Asn Asp Leu Gly Asp Leu Gly 
        915                 920                 925             


Val Met Met Phe Cys Glu Val Leu Lys Gln Gln Ser Cys Leu Leu Gln 
    930                 935                 940                 


Asn Leu Gly Leu Ser Glu Met Tyr Phe Asn Tyr Glu Thr Lys Ser Ala 
945                 950                 955                 960 


Leu Glu Thr Leu Gln Glu Glu Lys Pro Glu Leu Thr Val Val Phe Glu 
                965                 970                 975     


Pro Ser Trp 
            


<210>  994
<211>  933
<212>  PRT
<213>  Homo Sapiens

<400>  994

Glu Leu Leu Leu Pro Gln Glu Thr Thr Val Glu Leu Ser Cys Gly Val 
1               5                   10                  15      


Gly Pro Leu Gln Val Ile Leu Gly Pro Glu Gln Ala Ala Val Leu Asn 
            20                  25                  30          


Cys Ser Leu Gly Ala Ala Ala Ala Gly Pro Pro Thr Arg Val Thr Trp 
        35                  40                  45              


Ser Lys Asp Gly Asp Thr Leu Leu Glu His Asp His Leu His Leu Leu 
    50                  55                  60                  


Pro Asn Gly Ser Leu Trp Leu Ser Gln Pro Leu Ala Pro Asn Gly Ser 
65                  70                  75                  80  


Asp Glu Ser Val Pro Glu Ala Val Gly Val Ile Glu Gly Asn Tyr Ser 
                85                  90                  95      


Cys Leu Ala His Gly Pro Leu Gly Val Leu Ala Ser Gln Thr Ala Val 
            100                 105                 110         


Val Lys Leu Ala Thr Leu Ala Asp Phe Ser Leu His Pro Glu Ser Gln 
        115                 120                 125             


Thr Val Glu Glu Asn Gly Thr Ala Arg Phe Glu Cys His Ile Glu Gly 
    130                 135                 140                 


Leu Pro Ala Pro Ile Ile Thr Trp Glu Lys Asp Gln Val Thr Leu Pro 
145                 150                 155                 160 


Glu Glu Pro Arg Leu Ile Val Leu Pro Asn Gly Val Leu Gln Ile Leu 
                165                 170                 175     


Asp Val Gln Glu Ser Asp Ala Gly Pro Tyr Arg Cys Val Ala Thr Asn 
            180                 185                 190         


Ser Ala Arg Gln His Phe Ser Gln Glu Ala Leu Leu Ser Val Ala His 
        195                 200                 205             


Arg Gly Ser Leu Ala Ser Thr Arg Gly Gln Asp Val Val Ile Val Ala 
    210                 215                 220                 


Ala Pro Glu Asn Thr Thr Val Val Ser Gly Gln Ser Val Val Met Glu 
225                 230                 235                 240 


Cys Val Ala Ser Ala Asp Pro Thr Pro Phe Val Ser Trp Val Arg Gln 
                245                 250                 255     


Asp Gly Lys Pro Ile Ser Thr Asp Val Ile Val Leu Gly Arg Thr Asn 
            260                 265                 270         


Leu Leu Ile Ala Asn Ala Gln Pro Trp His Ser Gly Val Tyr Val Cys 
        275                 280                 285             


Arg Ala Asn Lys Pro Arg Thr Arg Asp Phe Ala Thr Ala Ala Ala Glu 
    290                 295                 300                 


Leu Arg Val Leu Ala Ala Pro Ala Ile Thr Gln Ala Pro Glu Ala Leu 
305                 310                 315                 320 


Ser Arg Thr Arg Ala Ser Thr Ala Arg Phe Val Cys Arg Ala Ser Gly 
                325                 330                 335     


Glu Pro Arg Pro Ala Leu Arg Trp Leu His Asn Gly Ala Pro Leu Arg 
            340                 345                 350         


Pro Asn Gly Arg Val Lys Val Gln Gly Gly Gly Gly Ser Leu Val Ile 
        355                 360                 365             


Thr Gln Ile Gly Leu Gln Asp Ala Gly Tyr Tyr Gln Cys Val Ala Glu 
    370                 375                 380                 


Asn Ser Ala Gly Met Ala Cys Ala Ala Ala Ser Leu Ala Val Val Val 
385                 390                 395                 400 


Arg Glu Gly Leu Pro Ser Ala Pro Thr Arg Val Thr Ala Thr Pro Leu 
                405                 410                 415     


Ser Ser Ser Ala Val Leu Val Ala Trp Glu Arg Pro Glu Met His Ser 
            420                 425                 430         


Glu Gln Ile Ile Gly Phe Ser Leu His Tyr Gln Lys Ala Arg Gly Met 
        435                 440                 445             


Asp Asn Val Glu Tyr Gln Phe Ala Val Asn Asn Asp Thr Thr Glu Leu 
    450                 455                 460                 


Gln Val Arg Asp Leu Glu Pro Asn Thr Asp Tyr Glu Phe Tyr Val Val 
465                 470                 475                 480 


Ala Tyr Ser Gln Leu Gly Ala Ser Arg Thr Ser Thr Pro Ala Leu Val 
                485                 490                 495     


His Thr Leu Asp Asp Val Pro Ser Ala Ala Pro Gln Leu Ser Leu Ser 
            500                 505                 510         


Ser Pro Asn Pro Ser Asp Ile Arg Val Ala Trp Leu Pro Leu Pro Pro 
        515                 520                 525             


Ser Leu Ser Asn Gly Gln Val Val Lys Tyr Lys Ile Glu Tyr Gly Leu 
    530                 535                 540                 


Gly Lys Glu Asp Gln Ile Phe Ser Thr Glu Val Arg Gly Asn Glu Thr 
545                 550                 555                 560 


Gln Leu Met Leu Asn Ser Leu Gln Pro Asn Lys Val Tyr Arg Val Arg 
                565                 570                 575     


Ile Ser Ala Gly Thr Ala Ala Gly Phe Gly Ala Pro Ser Gln Trp Met 
            580                 585                 590         


His His Arg Thr Pro Ser Met His Asn Gln Ser His Val Pro Phe Ala 
        595                 600                 605             


Pro Ala Glu Leu Lys Val Gln Ala Lys Met Glu Ser Leu Val Val Ser 
    610                 615                 620                 


Trp Gln Pro Pro Pro His Pro Thr Gln Ile Ser Gly Tyr Lys Leu Tyr 
625                 630                 635                 640 


Trp Arg Glu Val Gly Ala Glu Glu Glu Ala Asn Gly Asp Arg Leu Pro 
                645                 650                 655     


Gly Gly Arg Gly Asp Gln Ala Trp Asp Val Gly Pro Val Arg Leu Lys 
            660                 665                 670         


Lys Lys Val Lys Gln Tyr Glu Leu Thr Gln Leu Val Pro Gly Arg Leu 
        675                 680                 685             


Tyr Glu Val Lys Leu Val Ala Phe Asn Lys His Glu Asp Gly Tyr Ala 
    690                 695                 700                 


Ala Val Trp Lys Gly Lys Thr Glu Lys Ala Pro Ala Pro Asp Met Pro 
705                 710                 715                 720 


Ile Gln Arg Gly Pro Pro Leu Pro Pro Ala His Val His Ala Glu Ser 
                725                 730                 735     


Asn Ser Ser Thr Ser Ile Trp Leu Arg Trp Lys Lys Pro Asp Phe Thr 
            740                 745                 750         


Thr Val Lys Ile Val Asn Tyr Thr Val Arg Phe Ser Pro Trp Gly Leu 
        755                 760                 765             


Arg Asn Ala Ser Leu Val Thr Tyr Tyr Thr Ser Ser Gly Glu Asp Ile 
    770                 775                 780                 


Leu Ile Gly Gly Leu Lys Pro Phe Thr Lys Tyr Glu Phe Ala Val Gln 
785                 790                 795                 800 


Ser His Gly Val Asp Met Asp Gly Pro Phe Gly Ser Val Val Glu Arg 
                805                 810                 815     


Ser Thr Leu Pro Asp Arg Pro Ser Thr Pro Pro Ser Asp Leu Arg Leu 
            820                 825                 830         


Ser Pro Leu Thr Pro Ser Thr Val Arg Leu His Trp Cys Pro Pro Thr 
        835                 840                 845             


Glu Pro Asn Gly Glu Ile Val Glu Tyr Leu Ile Leu Tyr Ser Ser Asn 
    850                 855                 860                 


His Thr Gln Pro Glu His Gln Trp Thr Leu Leu Thr Thr Gln Gly Asn 
865                 870                 875                 880 


Ile Phe Ser Ala Glu Val His Gly Leu Glu Ser Asp Thr Arg Tyr Phe 
                885                 890                 895     


Phe Lys Met Gly Ala Arg Thr Glu Val Gly Pro Gly Pro Phe Ser Arg 
            900                 905                 910         


Leu Gln Asp Val Ile Thr Leu Gln Glu Lys Leu Ser Asp Ser Leu Asp 
        915                 920                 925             


Met His Ser Val Thr 
    930             


<210>  995
<211>  1210
<212>  PRT
<213>  Homo Sapiens

<400>  995

Leu Gln Cys Arg Asp Gly Tyr Glu Pro Cys Val Asn Glu Gly Met Cys 
1               5                   10                  15      


Val Thr Tyr His Asn Gly Thr Gly Tyr Cys Lys Cys Pro Glu Gly Phe 
            20                  25                  30          


Leu Gly Glu Tyr Cys Gln His Arg Asp Pro Cys Glu Lys Asn Arg Cys 
        35                  40                  45              


Gln Asn Gly Gly Thr Cys Val Ala Gln Ala Met Leu Gly Lys Ala Thr 
    50                  55                  60                  


Cys Arg Cys Ala Ser Gly Phe Thr Gly Glu Asp Cys Gln Tyr Ser Thr 
65                  70                  75                  80  


Ser His Pro Cys Phe Val Ser Arg Pro Cys Leu Asn Gly Gly Thr Cys 
                85                  90                  95      


His Met Leu Ser Arg Asp Thr Tyr Glu Cys Thr Cys Gln Val Gly Phe 
            100                 105                 110         


Thr Gly Lys Glu Cys Gln Trp Thr Asp Ala Cys Leu Ser His Pro Cys 
        115                 120                 125             


Ala Asn Gly Ser Thr Cys Thr Thr Val Ala Asn Gln Phe Ser Cys Lys 
    130                 135                 140                 


Cys Leu Thr Gly Phe Thr Gly Gln Lys Cys Glu Thr Asp Val Asn Glu 
145                 150                 155                 160 


Cys Asp Ile Pro Gly His Cys Gln His Gly Gly Thr Cys Leu Asn Leu 
                165                 170                 175     


Pro Gly Ser Tyr Gln Cys Gln Cys Pro Gln Gly Phe Thr Gly Gln Tyr 
            180                 185                 190         


Cys Asp Ser Leu Tyr Val Pro Cys Ala Pro Ser Pro Cys Val Asn Gly 
        195                 200                 205             


Gly Thr Cys Arg Gln Thr Gly Asp Phe Thr Phe Glu Cys Asn Cys Leu 
    210                 215                 220                 


Pro Gly Phe Glu Gly Ser Thr Cys Glu Arg Asn Ile Asp Asp Cys Pro 
225                 230                 235                 240 


Asn His Arg Cys Gln Asn Gly Gly Val Cys Val Asp Gly Val Asn Thr 
                245                 250                 255     


Tyr Asn Cys Arg Cys Pro Pro Gln Trp Thr Gly Gln Phe Cys Thr Glu 
            260                 265                 270         


Asp Val Asp Glu Cys Leu Leu Gln Pro Asn Ala Cys Gln Asn Gly Gly 
        275                 280                 285             


Thr Cys Ala Asn Arg Asn Gly Gly Tyr Gly Cys Val Cys Val Asn Gly 
    290                 295                 300                 


Trp Ser Gly Asp Asp Cys Ser Glu Asn Ile Asp Asp Cys Ala Phe Ala 
305                 310                 315                 320 


Ser Cys Thr Pro Gly Ser Thr Cys Ile Asp Arg Val Ala Ser Phe Ser 
                325                 330                 335     


Cys Met Cys Pro Glu Gly Lys Ala Gly Leu Leu Cys His Leu Asp Asp 
            340                 345                 350         


Ala Cys Ile Ser Asn Pro Cys His Lys Gly Ala Leu Cys Asp Thr Asn 
        355                 360                 365             


Pro Leu Asn Gly Gln Tyr Ile Cys Thr Cys Pro Gln Gly Tyr Lys Gly 
    370                 375                 380                 


Ala Asp Cys Thr Glu Asp Val Asp Glu Cys Ala Met Ala Asn Ser Asn 
385                 390                 395                 400 


Pro Cys Glu His Ala Gly Lys Cys Val Asn Thr Asp Gly Ala Phe His 
                405                 410                 415     


Cys Glu Cys Leu Lys Gly Tyr Ala Gly Pro Arg Cys Glu Met Asp Ile 
            420                 425                 430         


Asn Glu Cys His Ser Asp Pro Cys Gln Asn Asp Ala Thr Cys Leu Asp 
        435                 440                 445             


Lys Ile Gly Gly Phe Thr Cys Leu Cys Met Pro Gly Phe Lys Gly Val 
    450                 455                 460                 


His Cys Glu Leu Glu Ile Asn Glu Cys Gln Ser Asn Pro Cys Val Asn 
465                 470                 475                 480 


Asn Gly Gln Cys Val Asp Lys Val Asn Arg Phe Gln Cys Leu Cys Pro 
                485                 490                 495     


Pro Gly Phe Thr Gly Pro Val Cys Gln Ile Asp Ile Asp Asp Cys Ser 
            500                 505                 510         


Ser Thr Pro Cys Leu Asn Gly Ala Lys Cys Ile Asp His Pro Asn Gly 
        515                 520                 525             


Tyr Glu Cys Gln Cys Ala Thr Gly Phe Thr Gly Val Leu Cys Glu Glu 
    530                 535                 540                 


Asn Ile Asp Asn Cys Asp Pro Asp Pro Cys His His Gly Gln Cys Gln 
545                 550                 555                 560 


Asp Gly Ile Asp Ser Tyr Thr Cys Ile Cys Asn Pro Gly Tyr Met Gly 
                565                 570                 575     


Ala Ile Cys Ser Asp Gln Ile Asp Glu Cys Tyr Ser Ser Pro Cys Leu 
            580                 585                 590         


Asn Asp Gly Arg Cys Ile Asp Leu Val Asn Gly Tyr Gln Cys Asn Cys 
        595                 600                 605             


Gln Pro Gly Thr Ser Gly Val Asn Cys Glu Ile Asn Phe Asp Asp Cys 
    610                 615                 620                 


Ala Ser Asn Pro Cys Ile His Gly Ile Cys Met Asp Gly Ile Asn Arg 
625                 630                 635                 640 


Tyr Ser Cys Val Cys Ser Pro Gly Phe Thr Gly Gln Arg Cys Asn Ile 
                645                 650                 655     


Asp Ile Asp Glu Cys Ala Ser Asn Pro Cys Arg Lys Gly Ala Thr Cys 
            660                 665                 670         


Ile Asn Gly Val Asn Gly Phe Arg Cys Ile Cys Pro Glu Gly Pro His 
        675                 680                 685             


His Pro Ser Cys Tyr Ser Gln Val Asn Glu Cys Leu Ser Asn Pro Cys 
    690                 695                 700                 


Ile His Gly Asn Cys Thr Gly Gly Leu Ser Gly Tyr Lys Cys Leu Cys 
705                 710                 715                 720 


Asp Ala Gly Trp Val Gly Ile Asn Cys Glu Val Asp Lys Asn Glu Cys 
                725                 730                 735     


Leu Ser Asn Pro Cys Gln Asn Gly Gly Thr Cys Asp Asn Leu Val Asn 
            740                 745                 750         


Gly Tyr Arg Cys Thr Cys Lys Lys Gly Phe Lys Gly Tyr Asn Cys Gln 
        755                 760                 765             


Val Asn Ile Asp Glu Cys Ala Ser Asn Pro Cys Leu Asn Gln Gly Thr 
    770                 775                 780                 


Cys Phe Asp Asp Ile Ser Gly Tyr Thr Cys His Cys Val Leu Pro Tyr 
785                 790                 795                 800 


Thr Gly Lys Asn Cys Gln Thr Val Leu Ala Pro Cys Ser Pro Asn Pro 
                805                 810                 815     


Cys Glu Asn Ala Ala Val Cys Lys Glu Ser Pro Asn Phe Glu Ser Tyr 
            820                 825                 830         


Thr Cys Leu Cys Ala Pro Gly Trp Gln Gly Gln Arg Cys Thr Ile Asp 
        835                 840                 845             


Ile Asp Glu Cys Ile Ser Lys Pro Cys Met Asn His Gly Leu Cys His 
    850                 855                 860                 


Asn Thr Gln Gly Ser Tyr Met Cys Glu Cys Pro Pro Gly Phe Ser Gly 
865                 870                 875                 880 


Met Asp Cys Glu Glu Asp Ile Asp Asp Cys Leu Ala Asn Pro Cys Gln 
                885                 890                 895     


Asn Gly Gly Ser Cys Met Asp Gly Val Asn Thr Phe Ser Cys Leu Cys 
            900                 905                 910         


Leu Pro Gly Phe Thr Gly Asp Lys Tyr Gln Thr Asp Met Asn Glu Cys 
        915                 920                 925             


Leu Ser Glu Pro Cys Lys Asn Gly Gly Thr Cys Ser Asp Tyr Val Asn 
    930                 935                 940                 


Ser Tyr Thr Cys Lys Cys Gln Ala Gly Phe Asp Gly Val His Cys Glu 
945                 950                 955                 960 


Asn Asn Ile Asn Glu Cys Thr Glu Ser Ser Cys Phe Asn Gly Gly Thr 
                965                 970                 975     


Cys Val Asp Gly Ile Asn Ser Phe Ser Cys Leu Cys Pro Val Gly Phe 
            980                 985                 990         


Thr Gly Ser Phe Cys Leu His Glu  Ile Asn Glu Cys Ser  Ser His Pro 
        995                 1000                 1005             


Cys Leu  Asn Glu Gly Thr Cys  Val Asp Gly Leu Gly  Thr Tyr Arg 
    1010                 1015                 1020             


Cys Ser  Cys Pro Leu Gly Tyr  Thr Gly Lys Asn Cys  Gln Thr Leu 
    1025                 1030                 1035             


Val Asn  Leu Cys Ser Arg Ser  Pro Cys Lys Asn Lys  Gly Thr Cys 
    1040                 1045                 1050             


Val Gln  Lys Lys Ala Glu Ser  Gln Cys Leu Cys Pro  Ser Gly Trp 
    1055                 1060                 1065             


Ala Gly  Ala Tyr Cys Asp Val  Pro Asn Val Ser Cys  Asp Ile Ala 
    1070                 1075                 1080             


Ala Ser  Arg Arg Gly Val Leu  Val Glu His Leu Cys  Gln His Ser 
    1085                 1090                 1095             


Gly Val  Cys Ile Asn Ala Gly  Asn Thr His Tyr Cys  Gln Cys Pro 
    1100                 1105                 1110             


Leu Gly  Tyr Thr Gly Ser Tyr  Cys Glu Glu Gln Leu  Asp Glu Cys 
    1115                 1120                 1125             


Ala Ser  Asn Pro Cys Gln His  Gly Ala Thr Cys Ser  Asp Phe Ile 
    1130                 1135                 1140             


Gly Gly  Tyr Arg Cys Glu Cys  Val Pro Gly Tyr Gln  Gly Val Asn 
    1145                 1150                 1155             


Cys Glu  Tyr Glu Val Asp Glu  Cys Gln Asn Gln Pro  Cys Gln Asn 
    1160                 1165                 1170             


Gly Gly  Thr Cys Ile Asp Leu  Val Asn His Phe Lys  Cys Ser Cys 
    1175                 1180                 1185             


Pro Pro  Gly Thr Arg Gly Met  Lys Ser Ser Leu Ser  Ile Phe His 
    1190                 1195                 1200             


Pro Gly  His Cys Leu Lys Leu  
    1205                 1210 


<210>  996
<211>  236
<212>  PRT
<213>  Homo Sapiens

<400>  996

Met Cys Val Thr Tyr His Asn Gly Thr Gly Tyr Cys Lys Cys Pro Glu 
1               5                   10                  15      


Gly Phe Leu Gly Glu Tyr Cys Gln His Arg Asp Pro Cys Glu Lys Asn 
            20                  25                  30          


Arg Cys Gln Asn Gly Gly Thr Cys Val Ala Gln Ala Met Leu Gly Lys 
        35                  40                  45              


Ala Thr Cys Arg Cys Ala Ser Gly Phe Thr Gly Glu Asp Cys Gln Tyr 
    50                  55                  60                  


Ser Thr Ser His Pro Cys Phe Val Ser Arg Pro Cys Leu Asn Gly Gly 
65                  70                  75                  80  


Thr Cys His Met Leu Ser Arg Asp Thr Tyr Glu Cys Thr Cys Gln Val 
                85                  90                  95      


Gly Phe Thr Gly Lys Glu Cys Gln Trp Thr Asp Ala Cys Leu Ser His 
            100                 105                 110         


Pro Cys Ala Asn Gly Ser Thr Cys Thr Thr Val Ala Asn Gln Phe Ser 
        115                 120                 125             


Cys Lys Cys Leu Thr Gly Phe Thr Gly Gln Lys Cys Glu Thr Asp Val 
    130                 135                 140                 


Asn Glu Cys Asp Ile Pro Gly His Cys Gln His Gly Gly Thr Cys Leu 
145                 150                 155                 160 


Asn Leu Pro Gly Ser Tyr Gln Cys Gln Cys Leu Gln Gly Phe Thr Gly 
                165                 170                 175     


Gln Tyr Cys Asp Ser Leu Tyr Val Pro Cys Ala Pro Ser Pro Cys Val 
            180                 185                 190         


Asn Gly Gly Thr Cys Arg Gln Thr Gly Asp Phe Thr Phe Glu Cys Asn 
        195                 200                 205             


Cys Leu Pro Glu Thr Val Arg Arg Gly Thr Glu Leu Trp Glu Arg Asp 
    210                 215                 220                 


Arg Glu Val Trp Asn Gly Lys Glu His Asp Glu Asn 
225                 230                 235     


<210>  997
<211>  1424
<212>  PRT
<213>  Homo Sapiens

<400>  997

Arg Gly Leu Leu Cys Gly Ser Phe Pro Glu Pro Cys Ala Asn Gly Gly 
1               5                   10                  15      


Thr Cys Leu Ser Leu Ser Leu Gly Gln Gly Thr Cys Gln Cys Ala Pro 
            20                  25                  30          


Gly Phe Leu Gly Glu Thr Cys Gln Phe Pro Asp Pro Cys Gln Asn Ala 
        35                  40                  45              


Gln Leu Cys Gln Asn Gly Gly Ser Cys Gln Ala Leu Leu Pro Ala Pro 
    50                  55                  60                  


Leu Gly Leu Pro Ser Ser Pro Ser Pro Leu Thr Pro Ser Phe Leu Cys 
65                  70                  75                  80  


Thr Cys Leu Pro Gly Phe Thr Gly Glu Arg Cys Gln Ala Lys Leu Glu 
                85                  90                  95      


Asp Pro Cys Pro Pro Ser Phe Cys Ser Lys Arg Gly Arg Cys His Ile 
            100                 105                 110         


Gln Ala Ser Gly Arg Pro Gln Cys Ser Cys Met Pro Gly Trp Thr Gly 
        115                 120                 125             


Glu Gln Cys Gln Leu Arg Asp Phe Cys Ser Ala Asn Pro Cys Val Asn 
    130                 135                 140                 


Gly Gly Val Cys Leu Ala Thr Tyr Pro Gln Ile Gln Cys His Cys Pro 
145                 150                 155                 160 


Pro Gly Phe Glu Gly His Ala Cys Glu Arg Asp Val Asn Glu Cys Phe 
                165                 170                 175     


Gln Asp Pro Gly Pro Cys Pro Lys Gly Thr Ser Cys His Asn Thr Leu 
            180                 185                 190         


Gly Ser Phe Gln Cys Leu Cys Pro Val Gly Gln Glu Gly Pro Arg Cys 
        195                 200                 205             


Glu Leu Arg Ala Gly Pro Cys Pro Pro Arg Gly Cys Ser Asn Gly Gly 
    210                 215                 220                 


Thr Cys Gln Leu Met Pro Glu Lys Asp Ser Thr Phe His Leu Cys Leu 
225                 230                 235                 240 


Cys Pro Pro Gly Phe Ile Gly Pro Asp Cys Glu Val Asn Pro Asp Asn 
                245                 250                 255     


Cys Val Ser His Gln Cys Gln Asn Gly Gly Thr Cys Gln Asp Gly Leu 
            260                 265                 270         


Asp Thr Tyr Thr Cys Leu Cys Pro Glu Thr Trp Thr Gly Trp Asp Cys 
        275                 280                 285             


Ser Glu Asp Val Asp Glu Cys Glu Thr Gln Gly Pro Pro His Cys Arg 
    290                 295                 300                 


Asn Gly Gly Thr Cys Gln Asn Ser Ala Gly Ser Phe His Cys Val Cys 
305                 310                 315                 320 


Val Ser Gly Trp Gly Gly Thr Ser Cys Glu Glu Asn Leu Asp Asp Cys 
                325                 330                 335     


Ile Ala Ala Thr Cys Ala Pro Gly Ser Thr Cys Ile Asp Arg Val Gly 
            340                 345                 350         


Ser Phe Ser Cys Leu Cys Pro Pro Gly Arg Thr Gly Leu Leu Cys His 
        355                 360                 365             


Leu Glu Asp Met Cys Leu Ser Gln Pro Cys His Gly Asp Ala Gln Cys 
    370                 375                 380                 


Ser Thr Asn Pro Leu Thr Gly Ser Thr Leu Cys Leu Cys Gln Pro Gly 
385                 390                 395                 400 


Tyr Ser Gly Pro Thr Cys His Gln Asp Leu Asp Glu Cys Leu Met Ala 
                405                 410                 415     


Gln Gln Gly Pro Ser Pro Cys Glu His Gly Gly Ser Cys Leu Asn Thr 
            420                 425                 430         


Pro Gly Ser Phe Asn Cys Leu Cys Pro Pro Gly Tyr Thr Gly Ser Arg 
        435                 440                 445             


Cys Glu Ala Asp His Asn Glu Cys Leu Ser Gln Pro Cys His Pro Gly 
    450                 455                 460                 


Ser Thr Cys Leu Asp Leu Leu Ala Thr Phe His Cys Leu Cys Pro Pro 
465                 470                 475                 480 


Gly Leu Glu Gly Gln Leu Cys Glu Val Glu Thr Asn Glu Cys Ala Ser 
                485                 490                 495     


Ala Pro Cys Leu Asn His Ala Asp Cys His Asp Leu Leu Asn Gly Phe 
            500                 505                 510         


Gln Cys Ile Cys Leu Pro Gly Phe Ser Gly Thr Arg Cys Glu Glu Asp 
        515                 520                 525             


Ile Asp Glu Cys Arg Ser Ser Pro Cys Ala Asn Gly Gly Gln Cys Gln 
    530                 535                 540                 


Asp Gln Pro Gly Ala Phe His Cys Lys Cys Leu Pro Gly Phe Glu Gly 
545                 550                 555                 560 


Pro Arg Cys Gln Thr Glu Val Asp Glu Cys Leu Ser Asp Pro Cys Pro 
                565                 570                 575     


Val Gly Ala Ser Cys Leu Asp Leu Pro Gly Ala Phe Phe Cys Leu Cys 
            580                 585                 590         


Pro Ser Gly Phe Thr Gly Gln Leu Cys Glu Val Pro Leu Cys Ala Pro 
        595                 600                 605             


Asn Leu Cys Gln Pro Lys Gln Ile Cys Lys Asp Gln Lys Asp Lys Ala 
    610                 615                 620                 


Asn Cys Leu Cys Pro Asp Gly Ser Pro Gly Cys Ala Pro Pro Glu Asp 
625                 630                 635                 640 


Asn Cys Thr Cys His His Gly His Cys Gln Arg Ser Ser Cys Val Cys 
                645                 650                 655     


Asp Val Gly Trp Thr Gly Pro Glu Cys Glu Ala Glu Leu Gly Gly Cys 
            660                 665                 670         


Ile Ser Ala Pro Cys Ala His Gly Gly Thr Cys Tyr Pro Gln Pro Ser 
        675                 680                 685             


Gly Tyr Asn Cys Thr Cys Pro Thr Gly Tyr Thr Gly Pro Thr Cys Ser 
    690                 695                 700                 


Glu Glu Met Thr Ala Cys His Ser Gly Pro Cys Leu Asn Gly Gly Ser 
705                 710                 715                 720 


Cys Asn Pro Ser Pro Gly Gly Tyr Tyr Cys Thr Cys Pro Pro Ser His 
                725                 730                 735     


Thr Gly Pro Gln Cys Gln Thr Ser Thr Asp Tyr Cys Val Ser Ala Pro 
            740                 745                 750         


Cys Phe Asn Gly Gly Thr Cys Val Asn Arg Pro Gly Thr Phe Ser Cys 
        755                 760                 765             


Leu Cys Ala Met Gly Phe Gln Gly Pro Arg Cys Glu Gly Lys Leu Arg 
    770                 775                 780                 


Pro Ser Cys Ala Asp Ser Pro Cys Arg Asn Arg Ala Thr Cys Gln Asp 
785                 790                 795                 800 


Ser Pro Gln Gly Pro Arg Cys Leu Cys Pro Thr Gly Tyr Thr Gly Gly 
                805                 810                 815     


Ser Cys Gln Thr Leu Met Asp Leu Cys Ala Gln Lys Pro Cys Pro Arg 
            820                 825                 830         


Asn Ser His Cys Leu Gln Thr Gly Pro Ser Phe His Cys Leu Cys Leu 
        835                 840                 845             


Gln Gly Trp Thr Gly Pro Leu Cys Asn Leu Pro Leu Ser Ser Cys Gln 
    850                 855                 860                 


Lys Ala Ala Leu Ser Gln Gly Ile Asp Val Ser Ser Leu Cys His Asn 
865                 870                 875                 880 


Gly Gly Leu Cys Val Asp Ser Gly Pro Ser Tyr Phe Cys His Cys Pro 
                885                 890                 895     


Pro Gly Phe Gln Gly Ser Leu Cys Gln Asp His Val Asn Pro Cys Glu 
            900                 905                 910         


Ser Arg Pro Cys Gln Asn Gly Ala Thr Cys Met Ala Gln Pro Ser Gly 
        915                 920                 925             


Tyr Leu Cys Gln Cys Ala Pro Gly Tyr Asp Gly Gln Asn Cys Ser Lys 
    930                 935                 940                 


Glu Leu Asp Ala Cys Gln Ser Gln Pro Cys His Asn His Gly Thr Cys 
945                 950                 955                 960 


Thr Pro Lys Pro Gly Gly Phe His Cys Ala Cys Pro Pro Gly Phe Val 
                965                 970                 975     


Gly Leu Arg Cys Glu Gly Asp Val Asp Glu Cys Leu Asp Gln Pro Cys 
            980                 985                 990         


His Pro Thr Gly Thr Ala Ala Cys  His Ser Leu Ala Asn  Ala Phe Tyr 
        995                 1000                 1005             


Cys Gln  Cys Leu Pro Gly His  Thr Gly Gln Trp Cys  Glu Val Glu 
    1010                 1015                 1020             


Ile Asp  Pro Cys His Ser Gln  Pro Cys Phe His Gly  Gly Thr Cys 
    1025                 1030                 1035             


Glu Ala  Thr Ala Gly Ser Pro  Leu Gly Phe Ile Cys  His Cys Pro 
    1040                 1045                 1050             


Lys Gly  Phe Glu Gly Pro Thr  Cys Ser His Arg Ala  Pro Ser Cys 
    1055                 1060                 1065             


Gly Phe  His His Cys His His  Gly Gly Leu Cys Leu  Pro Ser Pro 
    1070                 1075                 1080             


Lys Pro  Gly Phe Pro Pro Arg  Cys Ala Cys Leu Ser  Gly Tyr Gly 
    1085                 1090                 1095             


Gly Pro  Asp Cys Leu Thr Pro  Pro Ala Pro Lys Gly  Cys Gly Pro 
    1100                 1105                 1110             


Pro Ser  Pro Cys Leu Tyr Asn  Gly Ser Cys Ser Glu  Thr Thr Gly 
    1115                 1120                 1125             


Leu Gly  Gly Pro Gly Phe Arg  Cys Ser Cys Pro His  Ser Ser Pro 
    1130                 1135                 1140             


Gly Pro  Arg Cys Gln Lys Pro  Gly Ala Lys Gly Cys  Glu Gly Arg 
    1145                 1150                 1155             


Ser Gly  Asp Gly Ala Cys Asp  Ala Gly Cys Ser Gly  Pro Gly Gly 
    1160                 1165                 1170             


Asn Trp  Asp Gly Gly Asp Cys  Ser Leu Gly Val Pro  Asp Pro Trp 
    1175                 1180                 1185             


Lys Gly  Cys Pro Ser His Ser  Arg Cys Trp Leu Leu  Phe Arg Asp 
    1190                 1195                 1200             


Gly Gln  Cys His Pro Gln Cys  Asp Ser Glu Glu Cys  Leu Phe Asp 
    1205                 1210                 1215             


Gly Tyr  Asp Cys Glu Thr Pro  Pro Ala Cys Thr Pro  Ala Tyr Asp 
    1220                 1225                 1230             


Gln Tyr  Cys His Asp His Phe  His Asn Gly His Cys  Glu Lys Gly 
    1235                 1240                 1245             


Cys Asn  Thr Ala Glu Cys Gly  Trp Asp Gly Gly Asp  Cys Arg Pro 
    1250                 1255                 1260             


Glu Asp  Gly Asp Pro Glu Trp  Gly Pro Ser Leu Ala  Leu Leu Val 
    1265                 1270                 1275             


Val Leu  Ser Pro Pro Ala Leu  Asp Gln Gln Leu Phe  Ala Leu Ala 
    1280                 1285                 1290             


Arg Val  Leu Ser Leu Thr Leu  Arg Val Gly Leu Trp  Val Arg Lys 
    1295                 1300                 1305             


Asp Arg  Asp Gly Arg Asp Met  Val Tyr Pro Tyr Pro  Gly Ala Arg 
    1310                 1315                 1320             


Ala Glu  Glu Lys Leu Gly Gly  Thr Arg Asp Pro Thr  Tyr Gln Glu 
    1325                 1330                 1335             


Arg Ala  Ala Pro Gln Thr Gln  Pro Leu Gly Lys Glu  Thr Asp Ser 
    1340                 1345                 1350             


Leu Ser  Ala Gly Phe Val Val  Val Met Gly Val Asp  Leu Ser Arg 
    1355                 1360                 1365             


Cys Gly  Pro Asp His Pro Ala  Ser Arg Cys Pro Trp  Asp Pro Gly 
    1370                 1375                 1380             


Leu Leu  Leu Arg Phe Leu Ala  Ala Met Ala Ala Val  Gly Ala Leu 
    1385                 1390                 1395             


Glu Pro  Leu Leu Pro Gly Pro  Leu Leu Ala Val His  Pro His Ala 
    1400                 1405                 1410             


Gly Thr  Ala Pro Pro Ala Asn  Gln Leu Pro Trp 
    1415                 1420                 


<210>  998
<211>  1033
<212>  PRT
<213>  Homo Sapiens

<400>  998

Gln Leu Ala Ile Pro Ala Ser Val Pro Arg Gly Phe Trp Ala Leu Pro 
1               5                   10                  15      


Glu Asn Leu Thr Val Val Glu Gly Ala Ser Val Glu Leu Arg Cys Gly 
            20                  25                  30          


Val Ser Thr Pro Gly Ser Ala Val Gln Trp Ala Lys Asp Gly Leu Leu 
        35                  40                  45              


Leu Gly Pro Asp Pro Arg Ile Pro Gly Phe Pro Arg Tyr Arg Leu Glu 
    50                  55                  60                  


Gly Asp Pro Ala Arg Gly Glu Phe His Leu His Ile Glu Ala Cys Asp 
65                  70                  75                  80  


Leu Ser Asp Asp Ala Glu Tyr Glu Cys Gln Val Gly Arg Ser Glu Met 
                85                  90                  95      


Gly Pro Glu Leu Val Ser Pro Arg Val Ile Leu Ser Ile Leu Val Pro 
            100                 105                 110         


Pro Lys Leu Leu Leu Leu Thr Pro Glu Ala Gly Thr Met Val Thr Trp 
        115                 120                 125             


Val Ala Gly Gln Glu Tyr Val Val Asn Cys Val Ser Gly Asp Ala Lys 
    130                 135                 140                 


Pro Ala Pro Asp Ile Thr Ile Leu Leu Ser Gly Gln Thr Ile Ser Asp 
145                 150                 155                 160 


Ile Ser Ala Asn Val Asn Glu Gly Ser Gln Gln Lys Leu Phe Thr Val 
                165                 170                 175     


Glu Ala Thr Ala Arg Val Thr Pro Arg Ser Ser Asp Asn Arg Gln Leu 
            180                 185                 190         


Leu Val Cys Glu Ala Ser Ser Pro Ala Leu Glu Ala Pro Ile Lys Ala 
        195                 200                 205             


Ser Phe Thr Val Asn Val Leu Phe Pro Pro Gly Pro Pro Val Ile Glu 
    210                 215                 220                 


Trp Pro Gly Leu Asp Glu Gly His Val Arg Ala Gly Gln Ser Leu Glu 
225                 230                 235                 240 


Leu Pro Cys Val Ala Arg Gly Gly Asn Pro Leu Ala Thr Leu Gln Trp 
                245                 250                 255     


Leu Lys Asn Gly Gln Pro Val Ser Thr Ala Trp Gly Thr Glu His Thr 
            260                 265                 270         


Gln Ala Val Ala Arg Ser Val Leu Val Met Thr Val Arg Pro Glu Asp 
        275                 280                 285             


His Gly Ala Gln Leu Ser Cys Glu Ala His Asn Ser Val Ser Ala Gly 
    290                 295                 300                 


Thr Gln Glu His Gly Ile Thr Leu Gln Val Thr Phe Pro Pro Ser Ala 
305                 310                 315                 320 


Ile Ile Ile Leu Gly Ser Ala Ser Gln Thr Glu Asn Lys Asn Val Thr 
                325                 330                 335     


Leu Ser Cys Val Ser Lys Ser Ser Arg Pro Arg Val Leu Leu Arg Trp 
            340                 345                 350         


Trp Leu Gly Trp Arg Gln Leu Leu Pro Met Glu Glu Thr Val Met Asp 
        355                 360                 365             


Gly Leu His Gly Gly His Ile Ser Met Ser Asn Leu Thr Phe Leu Ala 
    370                 375                 380                 


Arg Arg Glu Asp Asn Gly Leu Thr Leu Thr Cys Glu Ala Phe Ser Glu 
385                 390                 395                 400 


Ala Phe Thr Lys Glu Thr Phe Lys Lys Ser Leu Ile Leu Asn Val Lys 
                405                 410                 415     


Tyr Pro Ala Gln Lys Leu Trp Ile Glu Gly Pro Pro Glu Gly Gln Lys 
            420                 425                 430         


Leu Arg Ala Gly Thr Arg Val Arg Leu Val Cys Leu Ala Ile Gly Gly 
        435                 440                 445             


Asn Pro Glu Pro Ser Leu Met Trp Tyr Lys Asp Ser Arg Thr Val Thr 
    450                 455                 460                 


Glu Ser Arg Leu Pro Gln Glu Ser Arg Arg Val His Leu Gly Ser Val 
465                 470                 475                 480 


Glu Lys Ser Gly Ser Thr Phe Ser Arg Glu Leu Val Leu Val Thr Gly 
                485                 490                 495     


Pro Ser Asp Asn Gln Ala Lys Phe Thr Cys Lys Ala Gly Gln Leu Ser 
            500                 505                 510         


Ala Ser Thr Gln Leu Ala Val Gln Phe Pro Pro Thr Asn Val Thr Ile 
        515                 520                 525             


Leu Ala Asn Ala Ser Ala Leu Arg Pro Gly Asp Ala Leu Asn Leu Thr 
    530                 535                 540                 


Cys Val Ser Val Ser Ser Asn Pro Pro Val Asn Leu Ser Trp Asp Lys 
545                 550                 555                 560 


Glu Gly Glu Arg Leu Glu Gly Val Ala Ala Pro Pro Arg Arg Ala Pro 
                565                 570                 575     


Phe Lys Gly Ser Ala Ala Ala Arg Ser Val Leu Leu Gln Val Ser Ser 
            580                 585                 590         


Arg Asp His Gly Gln Arg Val Thr Cys Arg Ala His Ser Ala Glu Leu 
        595                 600                 605             


Arg Glu Thr Val Ser Ser Phe Tyr Arg Leu Asn Val Leu Tyr Arg Pro 
    610                 615                 620                 


Glu Phe Leu Gly Glu Gln Val Leu Val Val Thr Ala Val Glu Gln Gly 
625                 630                 635                 640 


Glu Ala Leu Leu Pro Val Ser Val Ser Ala Asn Pro Ala Pro Glu Ala 
                645                 650                 655     


Phe Asn Trp Thr Phe Arg Gly Tyr Arg Leu Ser Pro Ala Gly Gly Pro 
            660                 665                 670         


Arg His Arg Ile Leu Ser Ser Gly Ala Leu His Leu Trp Asn Val Thr 
        675                 680                 685             


Arg Ala Asp Asp Gly Leu Tyr Gln Leu His Cys Gln Asn Ser Glu Gly 
    690                 695                 700                 


Thr Ala Glu Ala Arg Leu Arg Leu Asp Val His Tyr Ala Pro Thr Ile 
705                 710                 715                 720 


Arg Ala Leu Gln Asp Pro Thr Glu Val Asn Val Gly Gly Ser Val Asp 
                725                 730                 735     


Ile Val Cys Thr Val Asp Ala Asn Pro Ile Leu Pro Gly Met Phe Asn 
            740                 745                 750         


Trp Glu Arg Leu Gly Glu Asp Glu Glu Asp Gln Ser Leu Asp Asp Met 
        755                 760                 765             


Glu Lys Ile Ser Arg Gly Pro Thr Gly Arg Leu Arg Ile His His Ala 
    770                 775                 780                 


Lys Leu Ala Gln Ala Gly Ala Tyr Gln Cys Ile Val Asp Asn Gly Val 
785                 790                 795                 800 


Ala Pro Pro Ala Arg Arg Leu Leu Arg Leu Val Val Arg Phe Ala Pro 
                805                 810                 815     


Gln Val Glu His Pro Thr Pro Leu Thr Lys Val Ala Ala Ala Gly Asp 
            820                 825                 830         


Ser Thr Ser Ser Ala Thr Leu His Cys Arg Ala Arg Gly Val Pro Asn 
        835                 840                 845             


Ile Val Phe Thr Trp Thr Lys Asn Gly Val Pro Leu Asp Leu Gln Asp 
    850                 855                 860                 


Pro Arg Tyr Thr Glu His Thr Tyr His Gln Gly Gly Val His Ser Ser 
865                 870                 875                 880 


Leu Leu Thr Ile Ala Asn Val Ser Ala Ala Gln Asp Tyr Ala Leu Phe 
                885                 890                 895     


Thr Cys Thr Ala Thr Asn Ala Leu Gly Ser Asp Gln Thr Asn Ile Gln 
            900                 905                 910         


Leu Val Ser Ile Ser Arg Pro Asp Pro Pro Ser Gly Leu Lys Val Val 
        915                 920                 925             


Ser Leu Thr Pro His Ser Val Gly Leu Glu Trp Lys Pro Gly Phe Asp 
    930                 935                 940                 


Gly Gly Leu Pro Gln Arg Phe Cys Ile Arg Tyr Glu Ala Leu Gly Thr 
945                 950                 955                 960 


Pro Gly Phe His Tyr Val Asp Val Val Pro Pro Gln Ala Thr Thr Phe 
                965                 970                 975     


Thr Leu Thr Gly Leu Gln Pro Ser Thr Arg Tyr Arg Val Trp Leu Leu 
            980                 985                 990         


Ala Ser Asn Ala Leu Gly Asp Ser  Gly Leu Ala Asp Lys  Gly Thr Gln 
        995                 1000                 1005             


Leu Pro  Ile Thr Thr Pro Gly  Leu His Gln Pro Ser  Gly Glu Pro 
    1010                 1015                 1020             


Glu Asp  Gln Leu Pro Thr Glu  Pro Pro Ser 
    1025                 1030             


<210>  999
<211>  546
<212>  PRT
<213>  Homo Sapiens

<400>  999

Glu Phe Asp Gly Arg Trp Pro Arg Gln Ile Val Ser Ser Ile Gly Leu 
1               5                   10                  15      


Cys Arg Tyr Gly Gly Arg Ile Asp Cys Cys Trp Gly Trp Ala Arg Gln 
            20                  25                  30          


Ser Trp Gly Gln Cys Gln Pro Val Cys Gln Pro Arg Cys Lys His Gly 
        35                  40                  45              


Glu Cys Ile Gly Pro Asn Lys Cys Lys Cys His Pro Gly Tyr Ala Gly 
    50                  55                  60                  


Lys Thr Cys Asn Gln Asp Leu Asn Glu Cys Gly Leu Lys Pro Arg Pro 
65                  70                  75                  80  


Cys Lys His Arg Cys Met Asn Thr Tyr Gly Ser Tyr Lys Cys Tyr Cys 
                85                  90                  95      


Leu Asn Gly Tyr Met Leu Met Pro Asp Gly Ser Cys Ser Ser Ala Leu 
            100                 105                 110         


Thr Cys Ser Met Ala Asn Cys Gln Tyr Gly Cys Asp Val Val Lys Gly 
        115                 120                 125             


Gln Ile Arg Cys Gln Cys Pro Ser Pro Gly Leu Gln Leu Ala Pro Asp 
    130                 135                 140                 


Gly Arg Thr Cys Val Asp Val Asp Glu Cys Ala Thr Gly Arg Ala Ser 
145                 150                 155                 160 


Cys Pro Arg Phe Arg Gln Cys Val Asn Thr Phe Gly Ser Tyr Ile Cys 
                165                 170                 175     


Lys Cys His Lys Gly Phe Asp Leu Met Tyr Ile Gly Gly Lys Tyr Gln 
            180                 185                 190         


Cys His Asp Ile Asp Glu Cys Ser Leu Gly Gln Tyr Gln Cys Ser Ser 
        195                 200                 205             


Phe Ala Arg Cys Tyr Asn Ile Arg Gly Ser Tyr Lys Cys Lys Cys Lys 
    210                 215                 220                 


Glu Gly Tyr Gln Gly Asp Gly Leu Thr Cys Val Tyr Ile Pro Lys Val 
225                 230                 235                 240 


Met Ile Glu Pro Ser Gly Pro Ile His Val Pro Lys Gly Asn Gly Thr 
                245                 250                 255     


Ile Leu Lys Gly Asp Thr Gly Asn Asn Asn Trp Ile Pro Asp Val Gly 
            260                 265                 270         


Ser Thr Trp Trp Pro Pro Lys Thr Pro Tyr Ile Pro Pro Ile Ile Thr 
        275                 280                 285             


Asn Arg Pro Thr Ser Lys Pro Thr Thr Arg Pro Thr Pro Lys Pro Thr 
    290                 295                 300                 


Pro Ile Pro Thr Pro Pro Pro Pro Pro Pro Leu Pro Thr Glu Leu Arg 
305                 310                 315                 320 


Thr Pro Leu Pro Pro Thr Thr Pro Glu Arg Pro Thr Thr Gly Leu Thr 
                325                 330                 335     


Thr Ile Ala Pro Ala Ala Ser Thr Pro Pro Gly Gly Ile Thr Val Asp 
            340                 345                 350         


Asn Arg Val Gln Thr Asp Pro Gln Lys Pro Arg Gly Asp Val Phe Ile 
        355                 360                 365             


Pro Arg Gln Pro Ser Asn Asp Leu Phe Glu Ile Phe Glu Ile Glu Arg 
    370                 375                 380                 


Gly Val Ser Ala Asp Asp Glu Ala Lys Asp Asp Pro Gly Val Leu Val 
385                 390                 395                 400 


His Ser Cys Asn Phe Asp His Gly Leu Cys Gly Trp Ile Arg Glu Lys 
                405                 410                 415     


Asp Asn Asp Leu His Trp Glu Pro Ile Arg Asp Pro Ala Gly Gly Gln 
            420                 425                 430         


Tyr Leu Thr Val Ser Ala Ala Lys Ala Pro Gly Gly Lys Ala Ala Arg 
        435                 440                 445             


Leu Val Leu Pro Leu Gly Arg Leu Met His Ser Gly Asp Leu Cys Leu 
    450                 455                 460                 


Ser Phe Arg His Lys Val Thr Gly Leu His Ser Gly Thr Leu Gln Val 
465                 470                 475                 480 


Phe Val Arg Lys His Gly Ala His Gly Ala Ala Leu Trp Gly Arg Asn 
                485                 490                 495     


Gly Gly His Gly Trp Arg Gln Thr Gln Ile Thr Leu Arg Gly Ala Asp 
            500                 505                 510         


Ile Lys Ser Val Val Phe Lys Gly Glu Lys Arg Arg Gly His Thr Gly 
        515                 520                 525             


Glu Ile Gly Leu Asp Asp Val Ser Leu Lys Lys Gly His Cys Ser Glu 
    530                 535                 540                 


Glu Arg 
545     


<210>  1000
<211>  195
<212>  PRT
<213>  Homo Sapiens

<400>  1000

Gln Asn Glu Pro Arg Ile Val Thr Ser Glu Glu Val Ile Ile Arg Asp 
1               5                   10                  15      


Ser Pro Val Leu Pro Val Thr Leu Gln Cys Asn Leu Thr Ser Ser Ser 
            20                  25                  30          


His Thr Leu Thr Tyr Ser Tyr Trp Thr Lys Asn Gly Val Glu Leu Ser 
        35                  40                  45              


Ala Thr Arg Lys Asn Ala Ser Asn Met Glu Tyr Arg Ile Asn Lys Pro 
    50                  55                  60                  


Arg Ala Glu Asp Ser Gly Glu Tyr His Cys Val Tyr His Phe Val Ser 
65                  70                  75                  80  


Ala Pro Lys Ala Asn Ala Thr Ile Glu Val Lys Ala Ala Pro Asp Ile 
                85                  90                  95      


Thr Gly His Lys Arg Ser Glu Asn Lys Asn Glu Gly Gln Asp Ala Thr 
            100                 105                 110         


Met Tyr Cys Lys Ser Val Gly Tyr Pro His Pro Asp Trp Ile Trp Arg 
        115                 120                 125             


Lys Lys Glu Asn Gly Met Pro Met Asp Ile Val Asn Thr Ser Gly Arg 
    130                 135                 140                 


Phe Phe Ile Ile Asn Lys Glu Asn Tyr Thr Glu Leu Asn Ile Val Asn 
145                 150                 155                 160 


Leu Gln Ile Thr Glu Asp Pro Gly Glu Tyr Glu Cys Asn Ala Thr Asn 
                165                 170                 175     


Ala Ile Gly Ser Ala Ser Val Val Thr Val Leu Arg Val Arg Ser His 
            180                 185                 190         


Leu Ala Pro 
        195 


<210>  1001
<211>  1031
<212>  PRT
<213>  Homo Sapiens

<400>  1001

Gln Met Ile Ser Ala Leu Glu Val Pro Leu Asp Pro Lys Leu Leu Glu 
1               5                   10                  15      


Asp Leu Val Gln Pro Pro Thr Ile Thr Gln Gln Ser Pro Lys Asp Tyr 
            20                  25                  30          


Ile Ile Asp Pro Arg Glu Asn Ile Val Ile Gln Cys Glu Ala Lys Gly 
        35                  40                  45              


Lys Pro Pro Pro Ser Phe Ser Trp Thr Arg Asn Gly Thr His Phe Asp 
    50                  55                  60                  


Ile Asp Lys Asp Pro Leu Val Thr Met Lys Pro Gly Thr Gly Thr Leu 
65                  70                  75                  80  


Ile Ile Asn Ile Met Ser Glu Gly Lys Ala Glu Thr Tyr Glu Gly Val 
                85                  90                  95      


Tyr Gln Cys Thr Ala Arg Asn Glu Arg Gly Ala Ala Val Ser Asn Asn 
            100                 105                 110         


Ile Val Val Arg Pro Ser Arg Ser Pro Leu Trp Thr Lys Glu Lys Leu 
        115                 120                 125             


Glu Pro Ile Thr Leu Gln Ser Gly Gln Ser Leu Val Leu Pro Cys Arg 
    130                 135                 140                 


Pro Pro Ile Gly Leu Pro Pro Pro Ile Ile Phe Trp Met Asp Asn Ser 
145                 150                 155                 160 


Phe Gln Arg Leu Pro Gln Ser Glu Arg Val Ser Gln Gly Leu Asn Gly 
                165                 170                 175     


Asp Leu Tyr Phe Ser Asn Val Leu Pro Glu Asp Thr Arg Glu Asp Tyr 
            180                 185                 190         


Ile Cys Tyr Ala Arg Phe Asn His Thr Gln Thr Ile Gln Gln Lys Gln 
        195                 200                 205             


Pro Ile Ser Val Lys Val Ile Ser Ala Lys Ser Ser Arg Glu Arg Pro 
    210                 215                 220                 


Pro Thr Phe Leu Thr Pro Glu Gly Asn Ala Ser Asn Lys Glu Glu Leu 
225                 230                 235                 240 


Arg Gly Asn Val Leu Ser Leu Glu Cys Ile Ala Glu Gly Leu Pro Thr 
                245                 250                 255     


Pro Ile Ile Tyr Trp Ala Lys Glu Asp Gly Met Leu Pro Lys Asn Arg 
            260                 265                 270         


Thr Val Tyr Lys Asn Phe Glu Lys Thr Leu Gln Ile Ile His Val Ser 
        275                 280                 285             


Glu Ala Asp Ser Gly Asn Tyr Gln Cys Ile Ala Lys Asn Ala Leu Gly 
    290                 295                 300                 


Ala Ile His His Thr Ile Ser Val Arg Val Lys Ala Ala Pro Tyr Trp 
305                 310                 315                 320 


Ile Thr Ala Pro Gln Asn Leu Val Leu Ser Pro Gly Glu Asp Gly Thr 
                325                 330                 335     


Leu Ile Cys Arg Ala Asn Gly Asn Pro Lys Pro Arg Ile Ser Trp Leu 
            340                 345                 350         


Thr Asn Gly Val Pro Ile Glu Ile Ala Pro Asp Asp Pro Ser Arg Lys 
        355                 360                 365             


Ile Asp Gly Asp Thr Ile Ile Phe Ser Asn Val Gln Glu Arg Ser Ser 
    370                 375                 380                 


Ala Val Tyr Gln Cys Asn Ala Ser Asn Glu Tyr Gly Tyr Leu Leu Ala 
385                 390                 395                 400 


Asn Ala Phe Val Asn Val Leu Ala Glu Pro Pro Arg Ile Leu Thr Pro 
                405                 410                 415     


Ala Asn Thr Leu Tyr Gln Val Ile Ala Asn Arg Pro Ala Leu Leu Asp 
            420                 425                 430         


Cys Ala Phe Phe Gly Ser Pro Leu Pro Thr Ile Glu Trp Phe Lys Gly 
        435                 440                 445             


Ala Lys Gly Ser Ala Leu His Glu Asp Ile Tyr Val Leu His Glu Asn 
    450                 455                 460                 


Gly Thr Leu Glu Ile Pro Val Ala Gln Lys Asp Ser Thr Gly Thr Tyr 
465                 470                 475                 480 


Thr Cys Val Ala Arg Asn Lys Leu Gly Met Ala Lys Asn Glu Val His 
                485                 490                 495     


Leu Glu Ile Lys Asp Ala Thr Trp Ile Val Lys Gln Pro Glu Tyr Ala 
            500                 505                 510         


Val Val Gln Arg Gly Ser Met Val Ser Phe Glu Cys Lys Val Lys His 
        515                 520                 525             


Asp His Thr Leu Ser Leu Thr Val Leu Trp Leu Lys Asp Asn Arg Glu 
    530                 535                 540                 


Leu Pro Ser Asp Glu Arg Phe Thr Val Asp Lys Asp His Leu Val Val 
545                 550                 555                 560 


Ala Asp Val Ser Asp Asp Asp Ser Gly Thr Tyr Thr Cys Val Ala Asn 
                565                 570                 575     


Thr Thr Leu Asp Ser Val Ser Ala Ser Ala Val Leu Ser Val Val Ala 
            580                 585                 590         


Pro Thr Pro Thr Pro Ala Pro Val Tyr Asp Val Pro Asn Pro Pro Phe 
        595                 600                 605             


Asp Leu Glu Leu Thr Asp Gln Leu Asp Lys Ser Val Gln Leu Ser Trp 
    610                 615                 620                 


Thr Pro Gly Asp Asp Asn Asn Ser Pro Ile Thr Lys Phe Ile Ile Glu 
625                 630                 635                 640 


Tyr Glu Asp Ala Met His Lys Pro Gly Leu Trp His His Gln Thr Glu 
                645                 650                 655     


Val Ser Gly Thr Gln Thr Thr Ala Gln Leu Lys Leu Ser Pro Tyr Val 
            660                 665                 670         


Asn Tyr Ser Phe Arg Val Met Ala Val Asn Ser Ile Gly Lys Ser Leu 
        675                 680                 685             


Pro Ser Glu Ala Ser Glu Gln Tyr Leu Thr Lys Ala Ser Glu Pro Asp 
    690                 695                 700                 


Lys Asn Pro Thr Ala Val Glu Gly Leu Gly Ser Glu Pro Asp Asn Leu 
705                 710                 715                 720 


Val Ile Thr Trp Lys Pro Leu Asn Gly Phe Glu Ser Asn Gly Pro Gly 
                725                 730                 735     


Leu Gln Tyr Lys Val Ser Trp Arg Gln Lys Asp Gly Asp Asp Glu Trp 
            740                 745                 750         


Thr Ser Val Val Val Ala Asn Val Ser Lys Tyr Ile Val Ser Gly Thr 
        755                 760                 765             


Pro Thr Phe Val Pro Tyr Leu Ile Lys Val Gln Ala Leu Asn Asp Met 
    770                 775                 780                 


Gly Phe Ala Pro Glu Pro Ala Val Val Met Gly His Ser Gly Glu Asp 
785                 790                 795                 800 


Leu Pro Met Val Ala Pro Gly Asn Val Arg Val Asn Val Val Asn Ser 
                805                 810                 815     


Thr Leu Ala Glu Val His Trp Asp Pro Val Pro Leu Lys Ser Ile Arg 
            820                 825                 830         


Gly His Leu Gln Gly Tyr Arg Ile Tyr Tyr Trp Lys Thr Gln Ser Ser 
        835                 840                 845             


Ser Lys Arg Asn Arg Arg His Ile Glu Lys Lys Ile Leu Thr Phe Gln 
    850                 855                 860                 


Gly Ser Lys Thr His Gly Met Leu Pro Gly Leu Glu Pro Phe Ser His 
865                 870                 875                 880 


Tyr Thr Leu Asn Val Arg Val Val Asn Gly Lys Gly Glu Gly Pro Ala 
                885                 890                 895     


Ser Pro Asp Arg Val Phe Asn Thr Pro Glu Gly Val Pro Ser Ala Pro 
            900                 905                 910         


Ser Ser Leu Lys Ile Val Asn Pro Thr Leu Asp Ser Leu Thr Leu Glu 
        915                 920                 925             


Trp Asp Pro Pro Ser His Pro Asn Gly Ile Leu Thr Glu Tyr Thr Leu 
    930                 935                 940                 


Lys Tyr Gln Pro Ile Asn Ser Thr His Glu Leu Gly Pro Leu Val Asp 
945                 950                 955                 960 


Leu Lys Ile Pro Ala Asn Lys Thr Arg Trp Thr Leu Lys Asn Leu Asn 
                965                 970                 975     


Phe Ser Thr Arg Tyr Lys Phe Tyr Phe Tyr Ala Gln Thr Ser Ala Gly 
            980                 985                 990         


Ser Gly Ser Gln Ile Thr Glu Glu  Ala Val Thr Thr Val  Asp Glu Ala 
        995                 1000                 1005             


Gly Ile  Leu Pro Pro Asp Val  Gly Ala Gly Lys Ala  Met Ala Ser 
    1010                 1015                 1020             


Arg Gln  Val Asp Ile Ala Thr  Gln 
    1025                 1030     


<210>  1002
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  1002

Ser Gly Lys Lys Pro Glu Ser Ala Ala Gly Ser Gln Ser Pro Ala Leu 
1               5                   10                  15      


Pro Pro Gln Leu Lys Glu Met Lys Ser Gln Glu Ser Ala Ala Gly Ser 
            20                  25                  30          


Lys Leu Val Leu Arg Cys Glu Thr Ser Ser Glu Tyr Ser Ser Leu Arg 
        35                  40                  45              


Phe Lys Trp Phe Lys Asn Gly Asn Glu Leu Asn Arg Lys Asn Lys Pro 
    50                  55                  60                  


Gln Asn Ile Lys Ile Gln Lys Lys Pro Gly Lys Ser Glu Leu Arg Ile 
65                  70                  75                  80  


Asn Lys Ala Ser Leu Ala Asp Ser Gly Glu Tyr Met Cys Lys Val Ile 
                85                  90                  95      


Ser Lys Leu Gly Asn Asp Ser Ala Ser Ala Asn Ile Thr Ile Val Glu 
            100                 105                 110         


Ser Asn Glu Ile Ile Thr Gly Met Pro Ala Ser Thr Glu Gly Ala Tyr 
        115                 120                 125             


Val Ser Ser Glu Ser Pro Ile Arg Ile Ser Val Ser Thr Glu Gly Ala 
    130                 135                 140                 


Asn Thr Ser Ser Ser Thr Ser Thr Ser Thr Thr Gly Thr Ser His Leu 
145                 150                 155                 160 


Val Lys Cys Ala Glu Lys Glu Lys Thr Phe Cys Val Asn Gly Gly Glu 
                165                 170                 175     


Cys Phe Met Val Lys Asp Leu Ser Asn Pro Ser Arg Tyr Leu Cys Lys 
            180                 185                 190         


Cys Gln Pro Gly Phe Thr Gly Ala Arg Cys Thr Glu Asn Val Pro Met 
        195                 200                 205             


Lys Val Gln Asn Gln Glu Lys Ala Glu Glu Leu Tyr Gln Lys Arg 
    210                 215                 220             


<210>  1003
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  1003

Asp Lys Ile Phe Glu Tyr Asp Ser Pro Thr His Leu Asp Pro Gly Gly 
1               5                   10                  15      


Leu Gly Gln Asp Pro Ile Ile Ser Leu Asp Ala Thr Ala Ala Ser Ala 
            20                  25                  30          


Leu Trp Val Ser Ser Glu Ala Tyr Thr Ser Pro Val Ser Arg Ala Gln 
        35                  40                  45              


Ser Glu Ser Glu Val Gln Val Thr Val Gln Gly Asp Lys Ala Val Val 
    50                  55                  60                  


Ser Phe Glu Pro Ser Ala Ala Pro Thr Pro Lys Asn Arg Ile Phe Ala 
65                  70                  75                  80  


Phe Ser Phe Leu Pro Ser Thr Ala Pro Ser Phe Pro Ser Pro Thr Arg 
                85                  90                  95      


Asn Pro Glu Val Arg Thr Pro Lys Ser Ala Thr Gln Pro Gln Thr Thr 
            100                 105                 110         


Glu Thr Asn Leu Gln Thr Ala Pro Lys Leu Ser Thr Ser Thr Ser Thr 
        115                 120                 125             


Thr Gly Thr Ser His Leu Val Lys Cys Ala Glu Lys Glu Lys Thr Phe 
    130                 135                 140                 


Cys Val Asn Gly Gly Glu Cys Phe Met Val Lys Asp Leu Ser Asn Pro 
145                 150                 155                 160 


Ser Arg Tyr Leu Cys Lys Cys Pro Asn Glu Phe Thr Gly Asp Arg Cys 
                165                 170                 175     


Gln Asn Tyr Val Met Ala Ser Phe Tyr Ser Thr Ser Thr Pro Phe Leu 
            180                 185                 190         


Ser Leu Pro Glu 
        195     


<210>  1004
<211>  294
<212>  PRT
<213>  Homo Sapiens

<400>  1004

Cys Tyr Ser Pro Ser Leu Lys Ser Val Gln Asp Gln Ala Tyr Lys Ala 
1               5                   10                  15      


Pro Val Val Val Glu Gly Lys Val Gln Gly Leu Val Pro Ala Gly Gly 
            20                  25                  30          


Ser Ser Ser Asn Ser Thr Arg Glu Pro Pro Ala Ser Gly Arg Val Ala 
        35                  40                  45              


Leu Val Lys Val Leu Asp Lys Trp Pro Leu Arg Ser Gly Gly Leu Gln 
    50                  55                  60                  


Arg Glu Gln Val Ile Ser Val Gly Ser Cys Val Pro Leu Glu Arg Asn 
65                  70                  75                  80  


Gln Arg Tyr Ile Phe Phe Leu Glu Pro Thr Glu Gln Pro Leu Val Phe 
                85                  90                  95      


Lys Thr Ala Phe Ala Pro Leu Asp Thr Asn Gly Lys Asn Leu Lys Lys 
            100                 105                 110         


Glu Val Gly Lys Ile Leu Cys Thr Asp Cys Ala Thr Arg Pro Lys Leu 
        115                 120                 125             


Lys Lys Met Lys Ser Gln Thr Gly Gln Val Gly Glu Lys Gln Ser Leu 
    130                 135                 140                 


Lys Cys Glu Ala Ala Ala Gly Asn Pro Gln Pro Ser Tyr Arg Trp Phe 
145                 150                 155                 160 


Lys Asp Gly Lys Glu Leu Asn Arg Ser Arg Asp Ile Arg Ile Lys Tyr 
                165                 170                 175     


Gly Asn Gly Arg Lys Asn Ser Arg Leu Gln Phe Asn Lys Val Lys Val 
            180                 185                 190         


Glu Asp Ala Gly Glu Tyr Val Cys Glu Ala Glu Asn Ile Leu Gly Lys 
        195                 200                 205             


Asp Thr Val Arg Gly Arg Leu Tyr Val Asn Ser Val Ser Thr Thr Leu 
    210                 215                 220                 


Ser Ser Trp Ser Gly His Ala Arg Lys Cys Asn Glu Thr Ala Lys Ser 
225                 230                 235                 240 


Tyr Cys Val Asn Gly Gly Val Cys Tyr Tyr Ile Glu Gly Ile Asn Gln 
                245                 250                 255     


Leu Ser Cys Lys Cys Pro Asn Gly Phe Phe Gly Gln Arg Cys Leu Glu 
            260                 265                 270         


Lys Leu Pro Leu Arg Leu Tyr Met Pro Asp Pro Lys Gln Lys Ala Glu 
        275                 280                 285             


Glu Leu Tyr Gln Lys Arg 
    290                 


<210>  1005
<211>  359
<212>  PRT
<213>  Homo Sapiens

<400>  1005

Met Ser Glu Gly Ala Ala Ala Ala Ser Pro Pro Gly Ala Ala Ser Ala 
1               5                   10                  15      


Ala Ala Ala Ser Ala Glu Glu Gly Thr Ala Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Ala Gly Gly Gly Pro Asp Gly Gly Gly Glu Gly Ala Ala Glu Pro 
        35                  40                  45              


Pro Arg Glu Leu Arg Cys Ser Asp Cys Ile Val Trp Asn Arg Gln Gln 
    50                  55                  60                  


Thr Trp Leu Cys Val Val Pro Leu Phe Ile Gly Phe Ile Gly Leu Gly 
65                  70                  75                  80  


Leu Ser Leu Met Leu Leu Lys Trp Ile Val Val Gly Ser Val Lys Glu 
                85                  90                  95      


Tyr Val Pro Thr Asp Leu Val Asp Ser Lys Gly Met Gly Gln Asp Pro 
            100                 105                 110         


Phe Phe Leu Ser Lys Pro Ser Ser Phe Pro Lys Ala Met Glu Thr Thr 
        115                 120                 125             


Thr Thr Thr Thr Ser Thr Thr Ser Pro Ala Thr Pro Ser Ala Gly Gly 
    130                 135                 140                 


Ala Ala Ser Ser Arg Thr Pro Asn Arg Ile Ser Thr Arg Leu Thr Thr 
145                 150                 155                 160 


Ile Thr Arg Ala Pro Thr Arg Phe Pro Gly His Arg Val Pro Ile Arg 
                165                 170                 175     


Ala Ser Pro Arg Ser Thr Thr Ala Arg Asn Thr Ala Ala Pro Ala Thr 
            180                 185                 190         


Val Pro Ser Thr Thr Ala Pro Phe Phe Ser Ser Ser Thr Leu Gly Ser 
        195                 200                 205             


Arg Pro Pro Val Pro Gly Thr Pro Ser Thr Gln Ala Met Pro Ser Trp 
    210                 215                 220                 


Pro Thr Ala Ala Tyr Ala Thr Ser Ser Tyr Leu His Asp Ser Thr Pro 
225                 230                 235                 240 


Ser Trp Thr Leu Ser Pro Phe Gln Asp Ala Ala Ser Ser Ser Ser Ser 
                245                 250                 255     


Ser Ser Ser Ser Ala Thr Thr Thr Thr Pro Glu Thr Ser Thr Ser Pro 
            260                 265                 270         


Lys Phe His Thr Thr Thr Tyr Ser Thr Glu Arg Ser Glu His Phe Lys 
        275                 280                 285             


Pro Cys Arg Asp Lys Asp Leu Ala Tyr Cys Leu Asn Asp Gly Glu Cys 
    290                 295                 300                 


Phe Val Ile Glu Thr Leu Thr Gly Ser His Lys His Cys Arg Cys Lys 
305                 310                 315                 320 


Glu Gly Tyr Gln Gly Val Arg Cys Asp Gln Phe Leu Pro Lys Thr Asp 
                325                 330                 335     


Ser Ile Leu Ser Asp Pro Asn His Leu Gly Ile Glu Phe Met Glu Ser 
            340                 345                 350         


Glu Glu Val Tyr Gln Arg Gln 
        355                 


<210>  1006
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  1006

Met Pro Thr Asp His Glu Glu Pro Cys Gly Pro Ser His Lys Ser Phe 
1               5                   10                  15      


Cys Leu Asn Gly Gly Leu Cys Tyr Val Ile Pro Thr Ile Pro Ser Pro 
            20                  25                  30          


Phe Cys Arg Cys Val Glu Asn Tyr Thr Gly Ala Arg Cys Glu Glu Val 
        35                  40                  45              


Phe Leu Pro Gly Ser Ser Ile Gln Thr Lys Ser Asn Leu 
    50                  55                  60      


<210>  1007
<211>  835
<212>  PRT
<213>  Homo Sapiens

<400>  1007

Phe Arg Asn Asp Lys Cys Gly Asp Thr Ile Lys Ile Glu Ser Pro Gly 
1               5                   10                  15      


Tyr Leu Thr Ser Pro Gly Tyr Pro His Ser Tyr His Pro Ser Glu Lys 
            20                  25                  30          


Cys Glu Trp Leu Ile Gln Ala Pro Asp Pro Tyr Gln Arg Ile Met Ile 
        35                  40                  45              


Asn Phe Asn Pro His Phe Asp Leu Glu Asp Arg Asp Cys Lys Tyr Asp 
    50                  55                  60                  


Tyr Val Glu Val Phe Asp Gly Glu Asn Glu Asn Gly His Phe Arg Gly 
65                  70                  75                  80  


Lys Phe Cys Gly Lys Ile Ala Pro Pro Pro Val Val Ser Ser Gly Pro 
                85                  90                  95      


Phe Leu Phe Ile Lys Phe Val Ser Asp Tyr Glu Thr His Gly Ala Gly 
            100                 105                 110         


Phe Ser Ile Arg Tyr Glu Ile Phe Lys Arg Gly Pro Glu Cys Ser Gln 
        115                 120                 125             


Asn Tyr Thr Thr Pro Ser Gly Val Ile Lys Ser Pro Gly Phe Pro Glu 
    130                 135                 140                 


Lys Tyr Pro Asn Ser Leu Glu Cys Thr Tyr Ile Val Phe Ala Pro Lys 
145                 150                 155                 160 


Met Ser Glu Ile Ile Leu Glu Phe Glu Ser Phe Asp Leu Glu Pro Asp 
                165                 170                 175     


Ser Asn Pro Pro Gly Gly Met Phe Cys Arg Tyr Asp Arg Leu Glu Ile 
            180                 185                 190         


Trp Asp Gly Phe Pro Gly Val Gly Pro His Ile Gly Arg Tyr Cys Gly 
        195                 200                 205             


Gln Lys Thr Pro Gly Arg Ile Arg Ser Ser Ser Gly Ile Leu Ser Met 
    210                 215                 220                 


Val Phe Tyr Thr Asp Ser Ala Ile Ala Lys Glu Gly Phe Ser Ala Asn 
225                 230                 235                 240 


Tyr Ser Val Leu Gln Ser Ser Val Ser Glu Asp Phe Lys Cys Met Glu 
                245                 250                 255     


Ala Leu Gly Met Glu Ser Gly Glu Ile His Ser Asp Gln Ile Thr Ala 
            260                 265                 270         


Ser Ser Gln Tyr Ser Thr Asn Trp Ser Ala Glu Arg Ser Arg Leu Asn 
        275                 280                 285             


Tyr Pro Glu Asn Gly Trp Thr Pro Gly Glu Asp Ser Tyr Arg Glu Trp 
    290                 295                 300                 


Ile Gln Val Asp Leu Gly Leu Leu Arg Phe Val Thr Ala Val Gly Thr 
305                 310                 315                 320 


Gln Gly Ala Ile Ser Lys Glu Thr Lys Lys Lys Tyr Tyr Val Lys Thr 
                325                 330                 335     


Tyr Lys Ile Asp Val Ser Ser Asn Gly Glu Asp Trp Ile Thr Ile Lys 
            340                 345                 350         


Glu Gly Asn Lys Pro Val Leu Phe Gln Gly Asn Thr Asn Pro Thr Asp 
        355                 360                 365             


Val Val Val Ala Val Phe Pro Lys Pro Leu Ile Thr Arg Phe Val Arg 
    370                 375                 380                 


Ile Lys Pro Ala Thr Trp Glu Thr Gly Ile Ser Met Arg Phe Glu Val 
385                 390                 395                 400 


Tyr Gly Cys Lys Ile Thr Asp Tyr Pro Cys Ser Gly Met Leu Gly Met 
                405                 410                 415     


Val Ser Gly Leu Ile Ser Asp Ser Gln Ile Thr Ser Ser Asn Gln Gly 
            420                 425                 430         


Asp Arg Asn Trp Met Pro Glu Asn Ile Arg Leu Val Thr Ser Arg Ser 
        435                 440                 445             


Gly Trp Ala Leu Pro Pro Ala Pro His Ser Tyr Ile Asn Glu Trp Leu 
    450                 455                 460                 


Gln Ile Asp Leu Gly Glu Glu Lys Ile Val Arg Gly Ile Ile Ile Gln 
465                 470                 475                 480 


Gly Gly Lys His Arg Glu Asn Lys Val Phe Met Arg Lys Phe Lys Ile 
                485                 490                 495     


Gly Tyr Ser Asn Asn Gly Ser Asp Trp Lys Met Ile Met Asp Asp Ser 
            500                 505                 510         


Lys Arg Lys Ala Lys Ser Phe Glu Gly Asn Asn Asn Tyr Asp Thr Pro 
        515                 520                 525             


Glu Leu Arg Thr Phe Pro Ala Leu Ser Thr Arg Phe Ile Arg Ile Tyr 
    530                 535                 540                 


Pro Glu Arg Ala Thr His Gly Gly Leu Gly Leu Arg Met Glu Leu Leu 
545                 550                 555                 560 


Gly Cys Glu Val Glu Ala Pro Thr Ala Gly Pro Thr Thr Pro Asn Gly 
                565                 570                 575     


Asn Leu Val Asp Glu Cys Asp Asp Asp Gln Ala Asn Cys His Ser Gly 
            580                 585                 590         


Thr Gly Asp Asp Phe Gln Leu Thr Gly Gly Thr Thr Val Pro Ala Thr 
        595                 600                 605             


Glu Lys Pro Thr Val Ile Asp Ser Thr Ile Gln Ser Glu Phe Pro Thr 
    610                 615                 620                 


Tyr Gly Phe Asn Cys Glu Phe Gly Trp Gly Ser His Lys Thr Phe Cys 
625                 630                 635                 640 


His Trp Glu His Asp Asn His Val Gln Leu Lys Trp Ser Val Leu Thr 
                645                 650                 655     


Ser Lys Thr Gly Pro Ile Gln Asp His Thr Gly Asp Gly Asn Phe Ile 
            660                 665                 670         


Tyr Ser Gln Ala Asp Glu Asn Gln Lys Gly Lys Val Ala Arg Leu Val 
        675                 680                 685             


Ser Pro Val Val Tyr Ser Gln Asn Ser Ala His Cys Met Thr Phe Trp 
    690                 695                 700                 


Tyr His Met Ser Gly Ser His Val Gly Thr Leu Arg Val Lys Leu Arg 
705                 710                 715                 720 


Tyr Gln Lys Pro Glu Glu Tyr Asp Gln Leu Val Trp Met Ala Ile Gly 
                725                 730                 735     


His Gln Gly Asp His Trp Lys Glu Gly Arg Val Leu Leu His Lys Ser 
            740                 745                 750         


Leu Lys Leu Tyr Gln Val Ile Phe Glu Gly Glu Ile Gly Lys Gly Asn 
        755                 760                 765             


Leu Gly Gly Ile Ala Val Asp Asp Ile Ser Ile Asn Asn His Ile Ser 
    770                 775                 780                 


Gln Glu Asp Cys Ala Lys Pro Ala Asp Leu Asp Lys Lys Asn Pro Glu 
785                 790                 795                 800 


Ile Lys Ile Asp Glu Thr Gly Ser Thr Pro Gly Tyr Glu Gly Glu Gly 
                805                 810                 815     


Glu Gly Asp Lys Asn Ile Ser Arg Lys Pro Gly Asn Val Leu Lys Thr 
            820                 825                 830         


Leu Asp Pro 
        835 


<210>  1008
<211>  839
<212>  PRT
<213>  Homo Sapiens

<400>  1008

Arg Gly Gln Pro Asp Pro Pro Cys Gly Gly Arg Leu Asn Ser Lys Asp 
1               5                   10                  15      


Ala Gly Tyr Ile Thr Ser Pro Gly Tyr Pro Gln Asp Tyr Pro Ser His 
            20                  25                  30          


Gln Asn Cys Glu Trp Ile Val Tyr Ala Pro Glu Pro Asn Gln Lys Ile 
        35                  40                  45              


Val Leu Asn Phe Asn Pro His Phe Glu Ile Glu Lys His Asp Cys Lys 
    50                  55                  60                  


Tyr Asp Phe Ile Glu Ile Arg Asp Gly Asp Ser Glu Ser Ala Asp Leu 
65                  70                  75                  80  


Leu Gly Lys His Cys Gly Asn Ile Ala Pro Pro Thr Ile Ile Ser Ser 
                85                  90                  95      


Gly Ser Met Leu Tyr Ile Lys Phe Thr Ser Asp Tyr Ala Arg Gln Gly 
            100                 105                 110         


Ala Gly Phe Ser Leu Arg Tyr Glu Ile Phe Lys Thr Gly Ser Glu Asp 
        115                 120                 125             


Cys Ser Lys Asn Phe Thr Ser Pro Asn Gly Thr Ile Glu Ser Pro Gly 
    130                 135                 140                 


Phe Pro Glu Lys Tyr Pro His Asn Leu Asp Cys Thr Phe Thr Ile Leu 
145                 150                 155                 160 


Ala Lys Pro Lys Met Glu Ile Ile Leu Gln Phe Leu Ile Phe Asp Leu 
                165                 170                 175     


Glu His Asp Pro Leu Gln Val Gly Glu Gly Asp Cys Lys Tyr Asp Trp 
            180                 185                 190         


Leu Asp Ile Trp Asp Gly Ile Pro His Val Gly Pro Leu Ile Gly Lys 
        195                 200                 205             


Tyr Cys Gly Thr Lys Thr Pro Ser Glu Leu Arg Ser Ser Thr Gly Ile 
    210                 215                 220                 


Leu Ser Leu Thr Phe His Thr Asp Met Ala Val Ala Lys Asp Gly Phe 
225                 230                 235                 240 


Ser Ala Arg Tyr Tyr Leu Val His Gln Glu Pro Leu Glu Asn Phe Gln 
                245                 250                 255     


Cys Asn Val Pro Leu Gly Met Glu Ser Gly Arg Ile Ala Asn Glu Gln 
            260                 265                 270         


Ile Ser Ala Ser Ser Thr Tyr Ser Asp Gly Arg Trp Thr Pro Gln Gln 
        275                 280                 285             


Ser Arg Leu His Gly Asp Asp Asn Gly Trp Thr Pro Asn Leu Asp Ser 
    290                 295                 300                 


Asn Lys Glu Tyr Leu Gln Val Asp Leu Arg Phe Leu Thr Met Leu Thr 
305                 310                 315                 320 


Ala Ile Ala Thr Gln Gly Ala Ile Ser Arg Glu Thr Gln Asn Gly Tyr 
                325                 330                 335     


Tyr Val Lys Ser Tyr Lys Leu Glu Val Ser Thr Asn Gly Glu Asp Trp 
            340                 345                 350         


Met Val Tyr Arg His Gly Lys Asn His Lys Val Phe Gln Ala Asn Asn 
        355                 360                 365             


Asp Ala Thr Glu Val Val Leu Asn Lys Leu His Ala Pro Leu Leu Thr 
    370                 375                 380                 


Arg Phe Val Arg Ile Arg Pro Gln Thr Trp His Ser Gly Ile Ala Leu 
385                 390                 395                 400 


Arg Leu Glu Leu Phe Gly Cys Arg Val Thr Asp Ala Pro Cys Ser Asn 
                405                 410                 415     


Met Leu Gly Met Leu Ser Gly Leu Ile Ala Asp Ser Gln Ile Ser Ala 
            420                 425                 430         


Ser Ser Thr Gln Glu Tyr Leu Trp Ser Pro Ser Ala Ala Arg Leu Val 
        435                 440                 445             


Ser Ser Arg Ser Gly Trp Phe Pro Arg Ile Pro Gln Ala Gln Pro Gly 
    450                 455                 460                 


Glu Glu Trp Leu Gln Val Asp Leu Gly Thr Pro Lys Thr Val Lys Gly 
465                 470                 475                 480 


Val Ile Ile Gln Gly Ala Arg Gly Gly Asp Ser Ile Thr Ala Val Glu 
                485                 490                 495     


Ala Arg Ala Phe Val Arg Lys Phe Lys Val Ser Tyr Ser Leu Asn Gly 
            500                 505                 510         


Lys Asp Trp Glu Tyr Ile Gln Asp Pro Arg Thr Gln Gln Pro Lys Leu 
        515                 520                 525             


Phe Glu Gly Asn Met His Tyr Asp Thr Pro Asp Ile Arg Arg Phe Asp 
    530                 535                 540                 


Pro Ile Pro Ala Gln Tyr Val Arg Val Tyr Pro Glu Arg Trp Ser Pro 
545                 550                 555                 560 


Ala Gly Ile Gly Met Arg Leu Glu Val Leu Gly Cys Asp Trp Thr Asp 
                565                 570                 575     


Ser Lys Pro Thr Val Glu Thr Leu Gly Pro Thr Val Lys Ser Glu Glu 
            580                 585                 590         


Thr Thr Thr Pro Tyr Pro Thr Glu Glu Glu Ala Thr Glu Cys Gly Glu 
        595                 600                 605             


Asn Cys Ser Phe Glu Asp Asp Lys Asp Leu Gln Leu Pro Ser Gly Phe 
    610                 615                 620                 


Asn Cys Asn Phe Asp Phe Leu Glu Glu Pro Cys Gly Trp Met Tyr Asp 
625                 630                 635                 640 


His Ala Lys Trp Leu Arg Thr Thr Trp Ala Ser Ser Ser Ser Pro Asn 
                645                 650                 655     


Asp Arg Thr Phe Pro Asp Asp Arg Asn Phe Leu Arg Leu Gln Ser Asp 
            660                 665                 670         


Ser Gln Arg Glu Gly Gln Tyr Ala Arg Leu Ile Ser Pro Pro Val His 
        675                 680                 685             


Leu Pro Arg Ser Pro Val Cys Met Glu Phe Gln Tyr Gln Ala Thr Gly 
    690                 695                 700                 


Gly Arg Gly Val Ala Leu Gln Val Val Arg Glu Ala Ser Gln Glu Ser 
705                 710                 715                 720 


Lys Leu Leu Trp Val Ile Arg Glu Asp Gln Gly Gly Glu Trp Lys His 
                725                 730                 735     


Gly Arg Ile Ile Leu Pro Ser Tyr Asp Met Glu Tyr Gln Ile Val Phe 
            740                 745                 750         


Glu Gly Val Ile Gly Lys Gly Arg Ser Gly Glu Ile Ala Ile Asp Asp 
        755                 760                 765             


Ile Arg Ile Ser Thr Asp Val Pro Leu Glu Asn Cys Met Glu Pro Ile 
    770                 775                 780                 


Ser Ala Phe Ala Val Asp Ile Pro Glu Ile His Glu Arg Glu Gly Tyr 
785                 790                 795                 800 


Glu Asp Glu Ile Asp Asp Glu Tyr Glu Val Asp Trp Ser Asn Ser Ser 
                805                 810                 815     


Ser Ala Thr Ser Gly Ser Gly Ala Pro Ser Thr Asp Lys Glu Lys Ser 
            820                 825                 830         


Trp Leu Tyr Thr Leu Asp Pro 
        835                 


<210>  1009
<211>  632
<212>  PRT
<213>  Homo Sapiens

<400>  1009

Trp Arg Asn Arg Ser Gly Thr Ala Thr Ala Ala Ser Gln Gly Val Cys 
1               5                   10                  15      


Lys Leu Val Gly Gly Ala Ala Asp Cys Arg Gly Gln Ser Leu Ala Ser 
            20                  25                  30          


Val Pro Ser Ser Leu Pro Pro His Ala Arg Met Leu Thr Leu Asp Ala 
        35                  40                  45              


Asn Pro Leu Lys Thr Leu Trp Asn His Ser Leu Gln Pro Tyr Pro Leu 
    50                  55                  60                  


Leu Glu Ser Leu Ser Leu His Ser Cys His Leu Glu Arg Ile Ser Arg 
65                  70                  75                  80  


Gly Ala Phe Gln Glu Gln Gly His Leu Arg Ser Leu Val Leu Gly Asp 
                85                  90                  95      


Asn Cys Leu Ser Glu Asn Tyr Glu Glu Thr Ala Ala Ala Leu His Ala 
            100                 105                 110         


Leu Pro Gly Leu Arg Arg Leu Asp Leu Ser Gly Asn Ala Leu Thr Glu 
        115                 120                 125             


Asp Met Ala Ala Leu Met Leu Gln Asn Leu Ser Ser Leu Arg Ser Val 
    130                 135                 140                 


Ser Leu Ala Gly Asn Thr Ile Met Arg Leu Asp Asp Ser Val Phe Glu 
145                 150                 155                 160 


Gly Leu Glu Arg Leu Arg Glu Leu Asp Leu Gln Arg Asn Tyr Ile Phe 
                165                 170                 175     


Glu Ile Glu Gly Gly Ala Phe Asp Gly Leu Ala Glu Leu Arg His Leu 
            180                 185                 190         


Asn Leu Ala Phe Asn Asn Leu Pro Cys Ile Val Asp Phe Gly Leu Thr 
        195                 200                 205             


Arg Leu Arg Val Leu Asn Val Ser Tyr Asn Val Leu Glu Trp Phe Leu 
    210                 215                 220                 


Ala Thr Gly Gly Glu Ala Ala Phe Glu Leu Glu Thr Leu Asp Leu Ser 
225                 230                 235                 240 


His Asn Gln Leu Leu Phe Phe Pro Leu Leu Pro Gln Tyr Ser Lys Leu 
                245                 250                 255     


Arg Thr Leu Leu Leu Arg Asp Asn Asn Met Gly Phe Tyr Arg Asp Leu 
            260                 265                 270         


Tyr Asn Thr Ser Ser Pro Arg Glu Met Val Ala Gln Phe Leu Leu Val 
        275                 280                 285             


Asp Gly Asn Val Thr Asn Ile Thr Thr Val Ser Leu Trp Glu Glu Phe 
    290                 295                 300                 


Ser Ser Ser Asp Leu Ala Asp Leu Arg Phe Leu Asp Met Ser Gln Asn 
305                 310                 315                 320 


Gln Phe Gln Tyr Leu Pro Asp Gly Phe Leu Arg Lys Met Pro Ser Leu 
                325                 330                 335     


Ser His Leu Asn Leu His Gln Asn Cys Leu Met Thr Leu His Ile Arg 
            340                 345                 350         


Glu His Glu Pro Pro Gly Ala Leu Thr Glu Leu Asp Leu Ser His Asn 
        355                 360                 365             


Gln Leu Ser Glu Leu His Leu Ala Pro Gly Leu Ala Ser Cys Leu Gly 
    370                 375                 380                 


Ser Leu Arg Leu Phe Asn Leu Ser Ser Asn Gln Leu Leu Gly Val Pro 
385                 390                 395                 400 


Pro Gly Leu Phe Ala Asn Ala Arg Asn Ile Thr Thr Leu Asp Met Ser 
                405                 410                 415     


His Asn Gln Ile Ser Leu Cys Pro Leu Pro Ala Ala Ser Asp Arg Val 
            420                 425                 430         


Gly Pro Pro Ser Cys Val Asp Phe Arg Asn Met Ala Ser Leu Arg Ser 
        435                 440                 445             


Leu Ser Leu Glu Gly Cys Gly Leu Gly Ala Leu Pro Asp Cys Pro Phe 
    450                 455                 460                 


Gln Gly Thr Ser Leu Thr Tyr Leu Asp Leu Ser Ser Asn Trp Gly Val 
465                 470                 475                 480 


Leu Asn Gly Ser Leu Ala Pro Leu Gln Asp Val Ala Pro Met Leu Gln 
                485                 490                 495     


Val Leu Ser Leu Arg Asn Met Gly Leu His Ser Ser Phe Met Ala Leu 
            500                 505                 510         


Asp Phe Ser Gly Phe Gly Asn Leu Arg Asp Leu Asp Leu Ser Gly Asn 
        515                 520                 525             


Cys Leu Thr Thr Phe Pro Arg Phe Gly Gly Ser Leu Ala Leu Glu Thr 
    530                 535                 540                 


Leu Asp Leu Arg Arg Asn Ser Leu Thr Ala Leu Pro Gln Lys Ala Val 
545                 550                 555                 560 


Ser Glu Gln Leu Ser Arg Gly Leu Arg Thr Ile Tyr Leu Ser Gln Asn 
                565                 570                 575     


Pro Tyr Asp Cys Cys Gly Val Asp Gly Trp Gly Ala Leu Gln His Gly 
            580                 585                 590         


Gln Thr Val Ala Asp Trp Ala Met Val Thr Cys Asn Leu Ser Ser Lys 
        595                 600                 605             


Ile Ile Arg Val Thr Glu Leu Pro Gly Gly Val Pro Arg Asp Cys Lys 
    610                 615                 620                 


Trp Glu Arg Leu Asp Leu Gly Leu 
625                 630         


<210>  1010
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  1010

Leu Glu Phe Pro Gly Ala Glu Gly Gln Trp Thr Arg Phe Pro Lys Trp 
1               5                   10                  15      


Asn Ala Cys Cys Glu Ser Glu Met Ser Phe Gln Leu Lys Thr Arg Ser 
            20                  25                  30          


Ala Arg Gly Leu Val Leu Tyr Phe Asp Asp Glu Gly Phe Cys Asp Phe 
        35                  40                  45              


Leu Glu Leu Ile Leu Thr Arg Gly Gly Arg Leu Gln Leu Ser Phe Ser 
    50                  55                  60                  


Val Phe Cys Ala Glu Pro Ala Thr Leu Leu Ala Asp Thr Pro Val Asn 
65                  70                  75                  80  


Asp Gly Ala Trp His Ser Val Arg Ile Arg Arg Gln Phe Arg Asn Thr 
                85                  90                  95      


Thr Leu Phe Ile Asp Gln Val Glu Ala Lys Trp Val Glu Val Lys Ser 
            100                 105                 110         


Lys Arg Arg Asp Met Thr Val Phe Ser Gly Leu Phe Val Gly Gly Leu 
        115                 120                 125             


Pro Pro Glu Leu Arg Ala Ala Ala Leu Lys Leu Thr Leu Ala Ser Val 
    130                 135                 140                 


Arg Glu Arg Glu Pro Phe Lys Gly Trp Ile Arg Asp Val Gly Val Asn 
145                 150                 155                 160 


Ser Ser Gln Val Leu Pro Val Asp Ser Gly Glu Val Lys Leu Asp Asp 
                165                 170                 175     


Glu Pro Pro Asn Ser Gly Gly Gly Ser Pro Cys Glu Ala Gly Glu Glu 
            180                 185                 190         


Gly Glu Gly Gly Val Cys Leu Asn Gly Gly Val Cys Ser Val Val Asp 
        195                 200                 205             


Asp Gln Ala Val Cys Asp Cys Ser Arg Thr Gly Phe Arg Gly Lys Asp 
    210                 215                 220                 


Cys Ser Gln Glu Asp Asn Asn Val Glu Gly Leu Ala His Leu Met Met 
225                 230                 235                 240 


Gly Asp Gln Gly Lys Ser Lys Asp 
                245             


<210>  1011
<211>  349
<212>  PRT
<213>  Homo Sapiens

<400>  1011

Ser Ser Asn Val Ala Ser Ser Ser Ser Thr Ser Ser Ser Pro Gly Ser 
1               5                   10                  15      


His Ser Gln His Glu His His Phe His Gly Ser Lys His His Ser Val 
            20                  25                  30          


Pro Ile Ser Ile Tyr Arg Ser Pro Val Ser Leu Arg Gly Gly His Ala 
        35                  40                  45              


Gly Ala Thr Tyr Ile Phe Gly Lys Ser Gly Gly Leu Ile Leu Tyr Thr 
    50                  55                  60                  


Trp Pro Ala Asn Asp Arg Pro Ser Thr Arg Ser Asp Arg Leu Ala Val 
65                  70                  75                  80  


Gly Phe Ser Thr Thr Val Lys Asp Gly Ile Leu Val Arg Ile Asp Ser 
                85                  90                  95      


Ala Pro Gly Leu Gly Asp Phe Leu Gln Leu His Ile Glu Gln Gly Lys 
            100                 105                 110         


Ile Gly Val Val Phe Asn Ile Gly Thr Val Asp Ile Ser Ile Lys Glu 
        115                 120                 125             


Glu Arg Thr Pro Val Asn Asp Gly Lys Tyr His Val Val Arg Phe Thr 
    130                 135                 140                 


Arg Asn Gly Gly Asn Ala Thr Leu Gln Val Asp Asn Trp Pro Val Asn 
145                 150                 155                 160 


Glu His Tyr Pro Thr Gly Asn Thr Asp Asn Glu Arg Phe Gln Met Val 
                165                 170                 175     


Lys Gln Lys Ile Pro Phe Lys Tyr Asn Arg Pro Val Glu Glu Trp Leu 
            180                 185                 190         


Gln Glu Lys Gly Arg Gln Leu Thr Ile Phe Asn Thr Gln Ala Gln Ile 
        195                 200                 205             


Ala Ile Gly Gly Lys Asp Lys Gly Arg Leu Phe Gln Gly Gln Leu Ser 
    210                 215                 220                 


Gly Leu Tyr Tyr Asp Gly Leu Lys Val Leu Asn Met Ala Ala Glu Asn 
225                 230                 235                 240 


Asn Pro Asn Ile Lys Ile Asn Gly Ser Val Arg Leu Val Gly Glu Val 
                245                 250                 255     


Pro Ser Ile Leu Gly Thr Thr Gln Thr Thr Ser Met Pro Pro Glu Met 
            260                 265                 270         


Ser Thr Thr Val Met Glu Thr Thr Thr Thr Met Ala Thr Thr Thr Thr 
        275                 280                 285             


Arg Lys Asn Arg Ser Thr Ala Ser Ile Gln Pro Thr Ser Asp Asp Leu 
    290                 295                 300                 


Val Ser Ser Ala Glu Cys Ser Ser Asp Asp Glu Asp Phe Val Glu Cys 
305                 310                 315                 320 


Glu Pro Ser Thr Ala Asn Pro Thr Glu Pro Gly Ile Arg Arg Val Pro 
                325                 330                 335     


Gly Ala Ser Glu Val Ile Arg Glu Ser Ser Ser Thr Thr 
            340                 345                 


<210>  1012
<211>  523
<212>  PRT
<213>  Homo Sapiens

<400>  1012

Trp Glu Leu Thr Ile Leu His Thr Asn Asp Val His Ser Arg Leu Glu 
1               5                   10                  15      


Gln Thr Ser Glu Asp Ser Ser Lys Cys Val Asn Ala Ser Arg Cys Met 
            20                  25                  30          


Gly Gly Val Ala Arg Leu Phe Thr Lys Val Gln Gln Ile Arg Arg Ala 
        35                  40                  45              


Glu Pro Asn Val Leu Leu Leu Asp Ala Gly Asp Gln Tyr Gln Gly Thr 
    50                  55                  60                  


Ile Trp Phe Thr Val Tyr Lys Gly Ala Glu Val Ala His Phe Met Asn 
65                  70                  75                  80  


Ala Leu Arg Tyr Asp Ala Met Ala Leu Gly Asn His Glu Phe Asp Asn 
                85                  90                  95      


Gly Val Glu Gly Leu Ile Glu Pro Leu Leu Lys Glu Ala Lys Phe Pro 
            100                 105                 110         


Ile Leu Ser Ala Asn Ile Lys Ala Lys Gly Pro Leu Ala Ser Gln Ile 
        115                 120                 125             


Ser Gly Leu Tyr Leu Pro Tyr Lys Val Leu Pro Val Gly Asp Glu Val 
    130                 135                 140                 


Val Gly Ile Val Gly Tyr Thr Ser Lys Glu Thr Pro Phe Leu Ser Asn 
145                 150                 155                 160 


Pro Gly Thr Asn Leu Val Phe Glu Asp Glu Ile Thr Ala Leu Gln Pro 
                165                 170                 175     


Glu Val Asp Lys Leu Lys Thr Leu Asn Val Asn Lys Ile Ile Ala Leu 
            180                 185                 190         


Gly His Ser Gly Phe Glu Met Asp Lys Leu Ile Ala Gln Lys Val Arg 
        195                 200                 205             


Gly Val Asp Val Val Val Gly Gly His Ser Asn Thr Phe Leu Tyr Thr 
    210                 215                 220                 


Gly Asn Pro Pro Ser Lys Glu Val Pro Ala Gly Lys Tyr Pro Phe Ile 
225                 230                 235                 240 


Val Thr Ser Asp Asp Gly Arg Lys Val Pro Val Val Gln Ala Tyr Ala 
                245                 250                 255     


Phe Gly Lys Tyr Leu Gly Tyr Leu Lys Ile Glu Phe Asp Glu Arg Gly 
            260                 265                 270         


Asn Val Ile Ser Ser His Gly Asn Pro Ile Leu Leu Asn Ser Ser Ile 
        275                 280                 285             


Pro Glu Asp Pro Ser Ile Lys Ala Asp Ile Asn Lys Trp Arg Ile Lys 
    290                 295                 300                 


Leu Asp Asn Tyr Ser Thr Gln Glu Leu Gly Lys Thr Ile Val Tyr Leu 
305                 310                 315                 320 


Asp Gly Ser Ser Gln Ser Cys Arg Phe Arg Glu Cys Asn Met Gly Asn 
                325                 330                 335     


Leu Ile Cys Asp Ala Met Ile Asn Asn Asn Leu Arg His Ala Asp Glu 
            340                 345                 350         


Thr Phe Trp Asn His Val Ser Met Cys Ile Leu Asn Gly Gly Gly Ile 
        355                 360                 365             


Arg Ser Pro Ile Asp Glu Arg Asn Asn Gly Thr Ile Thr Trp Glu Asn 
    370                 375                 380                 


Leu Ala Ala Val Leu Pro Phe Gly Gly Thr Phe Asp Leu Val Gln Leu 
385                 390                 395                 400 


Lys Gly Ser Thr Leu Lys Lys Ala Phe Glu His Ser Val His Arg Tyr 
                405                 410                 415     


Gly Gln Ser Thr Gly Glu Phe Leu Gln Val Gly Gly Ile His Val Val 
            420                 425                 430         


Tyr Asp Leu Ser Arg Lys Pro Gly Asp Arg Val Val Lys Leu Asp Val 
        435                 440                 445             


Leu Cys Thr Lys Cys Arg Val Pro Ser Tyr Asp Pro Leu Lys Met Asp 
    450                 455                 460                 


Glu Val Tyr Lys Val Ile Leu Pro Asn Phe Leu Ala Asn Gly Gly Asp 
465                 470                 475                 480 


Gly Phe Gln Met Ile Lys Asp Glu Leu Leu Arg His Asp Ser Gly Asp 
                485                 490                 495     


Gln Asp Ile Asn Val Val Ser Thr Tyr Ile Ser Lys Met Lys Val Ile 
            500                 505                 510         


Tyr Pro Ala Val Glu Gly Arg Ile Lys Phe Ser 
        515                 520             


<210>  1013
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1013

Tyr Ala Glu His Lys Ser His Arg Gly Glu Tyr Ser Val Cys Asp Ser 
1               5                   10                  15      


Glu Ser Leu Trp Val Thr Asp Lys Ser Ser Ala Ile Asp Ile Arg Gly 
            20                  25                  30          


His Gln Val Thr Val Leu Gly Glu Ile Lys Thr Gly Asn Ser Pro Val 
        35                  40                  45              


Lys Gln Tyr Phe Tyr Glu Thr Arg Cys Lys Glu Ala Arg Pro Val Lys 
    50                  55                  60                  


Asn Gly Cys Arg Gly Ile Asp Asp Lys His Trp Asn Ser Gln Cys Lys 
65                  70                  75                  80  


Thr Ser Gln Thr Tyr Val Arg Ala Leu Thr Ser Glu Asn Asn Lys Leu 
                85                  90                  95      


Val Gly Trp Arg Trp Ile Arg Ile Asp Thr Ser Cys Val Cys Ala Leu 
            100                 105                 110         


Ser Arg Lys Ile Gly Arg Thr 
        115                 


<210>  1014
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  1014

Gly Val Ser Glu Thr Ala Pro Ala Ser Arg Arg Gly Glu Leu Ala Val 
1               5                   10                  15      


Cys Asp Ala Val Ser Gly Trp Val Thr Asp Arg Arg Thr Ala Val Asp 
            20                  25                  30          


Leu Arg Gly Arg Glu Val Glu Val Leu Gly Glu Val Pro Ala Ala Gly 
        35                  40                  45              


Gly Ser Pro Leu Arg Gln Tyr Phe Phe Glu Thr Arg Cys Lys Ala Asp 
    50                  55                  60                  


Asn Ala Glu Glu Gly Gly Pro Gly Ala Gly Gly Gly Gly Cys Arg Gly 
65                  70                  75                  80  


Val Asp Arg Arg His Trp Val Ser Glu Cys Lys Ala Lys Gln Ser Tyr 
                85                  90                  95      


Val Arg Ala Leu Thr Ala Asp Ala Gln Gly Arg Val Gly Trp Arg Trp 
            100                 105                 110         


Ile Arg Ile Asp Thr Ala Cys Val Cys Thr Leu Leu Ser Arg Thr Gly 
        115                 120                 125             


Arg Ala 
    130 


<210>  1015
<211>  283
<212>  PRT
<213>  Homo Sapiens

<400>  1015

Gly Asp Ala Thr Phe Pro Lys Ala Met Asp Asn Val Thr Val Arg Gln 
1               5                   10                  15      


Gly Glu Ser Ala Thr Leu Arg Cys Thr Ile Asp Asn Arg Val Thr Arg 
            20                  25                  30          


Val Ala Trp Leu Asn Arg Ser Thr Ile Leu Tyr Ala Gly Asn Asp Lys 
        35                  40                  45              


Trp Cys Leu Asp Pro Arg Val Val Leu Leu Ser Asn Thr Gln Thr Gln 
    50                  55                  60                  


Tyr Ser Ile Glu Ile Gln Asn Val Asp Val Tyr Asp Glu Gly Pro Tyr 
65                  70                  75                  80  


Thr Cys Ser Val Gln Thr Asp Asn His Pro Lys Thr Ser Arg Val His 
                85                  90                  95      


Leu Ile Val Gln Val Ser Pro Lys Ile Val Glu Ile Ser Ser Asp Ile 
            100                 105                 110         


Ser Ile Asn Glu Gly Asn Asn Ile Ser Leu Thr Cys Ile Ala Thr Gly 
        115                 120                 125             


Arg Pro Glu Pro Thr Val Thr Trp Arg His Ile Ser Pro Lys Ala Val 
    130                 135                 140                 


Gly Phe Val Ser Glu Asp Glu Tyr Leu Glu Ile Gln Gly Ile Thr Arg 
145                 150                 155                 160 


Glu Gln Ser Gly Asp Tyr Glu Cys Ser Ala Ser Asn Asp Val Ala Ala 
                165                 170                 175     


Pro Val Val Arg Arg Val Lys Val Thr Val Asn Tyr Pro Pro Tyr Ile 
            180                 185                 190         


Ser Glu Ala Lys Gly Thr Gly Val Pro Val Gly Gln Lys Gly Thr Leu 
        195                 200                 205             


Gln Cys Glu Ala Ser Ala Val Pro Ser Ala Glu Phe Gln Trp Tyr Lys 
    210                 215                 220                 


Asp Asp Lys Arg Leu Ile Glu Gly Lys Lys Gly Val Lys Val Glu Asn 
225                 230                 235                 240 


Arg Pro Phe Leu Ser Lys Leu Ile Phe Phe Asn Val Ser Glu His Asp 
                245                 250                 255     


Tyr Gly Asn Tyr Thr Cys Val Ala Ser Asn Lys Leu Gly His Thr Asn 
            260                 265                 270         


Ala Ser Ile Met Leu Phe Gly Glu Thr Val Leu 
        275                 280             


<210>  1016
<211>  580
<212>  PRT
<213>  Homo Sapiens

<400>  1016

Gly Pro Gly Leu Ser Met Phe Ala Gly Gln Ala Ala Gln Pro Asp Pro 
1               5                   10                  15      


Cys Ser Asp Glu Asn Gly His Pro Arg Arg Cys Ile Pro Asp Phe Val 
            20                  25                  30          


Asn Ala Ala Phe Gly Lys Asp Val Arg Val Ser Ser Thr Cys Gly Arg 
        35                  40                  45              


Pro Pro Ala Arg Tyr Cys Val Val Ser Glu Arg Gly Glu Glu Arg Leu 
    50                  55                  60                  


Arg Ser Cys His Leu Cys Asn Ala Ser Asp Pro Lys Lys Ala His Pro 
65                  70                  75                  80  


Pro Ala Phe Leu Thr Asp Leu Asn Asn Pro His Asn Leu Thr Cys Trp 
                85                  90                  95      


Gln Ser Glu Asn Tyr Leu Gln Phe Pro His Asn Val Thr Leu Thr Leu 
            100                 105                 110         


Ser Leu Gly Lys Lys Phe Glu Val Thr Tyr Val Ser Leu Gln Phe Cys 
        115                 120                 125             


Ser Pro Arg Pro Glu Ser Met Ala Ile Tyr Lys Ser Met Asp Tyr Gly 
    130                 135                 140                 


Arg Thr Trp Val Pro Phe Gln Phe Tyr Ser Thr Gln Cys Arg Lys Met 
145                 150                 155                 160 


Tyr Asn Arg Pro His Arg Ala Pro Ile Thr Lys Gln Asn Glu Gln Glu 
                165                 170                 175     


Ala Val Cys Thr Asp Ser His Thr Asp Met Arg Pro Leu Ser Gly Gly 
            180                 185                 190         


Leu Ile Ala Phe Ser Thr Leu Asp Gly Arg Pro Ser Ala His Asp Phe 
        195                 200                 205             


Asp Asn Ser Pro Val Leu Gln Asp Trp Val Thr Ala Thr Asp Ile Arg 
    210                 215                 220                 


Val Ala Phe Ser Arg Leu His Thr Phe Gly Asp Glu Asn Glu Asp Asp 
225                 230                 235                 240 


Ser Glu Leu Ala Arg Asp Ser Tyr Phe Tyr Ala Val Ser Asp Leu Gln 
                245                 250                 255     


Val Gly Gly Arg Cys Lys Cys Asn Gly His Ala Ala Arg Cys Val Arg 
            260                 265                 270         


Asp Arg Asp Asp Ser Leu Val Cys Asp Cys Arg His Asn Thr Ala Gly 
        275                 280                 285             


Pro Glu Cys Asp Arg Cys Lys Pro Phe His Tyr Asp Arg Pro Trp Gln 
    290                 295                 300                 


Arg Ala Thr Ala Arg Glu Ala Asn Glu Cys Val Ala Cys Asn Cys Asn 
305                 310                 315                 320 


Leu His Ala Arg Arg Cys Arg Phe Asn Met Glu Leu Tyr Lys Leu Ser 
                325                 330                 335     


Gly Arg Lys Ser Gly Gly Val Cys Leu Asn Cys Arg His Asn Thr Ala 
            340                 345                 350         


Gly Arg His Cys His Tyr Cys Lys Glu Gly Tyr Tyr Arg Asp Met Gly 
        355                 360                 365             


Lys Pro Ile Thr His Arg Lys Ala Cys Lys Ala Cys Asp Cys His Pro 
    370                 375                 380                 


Val Gly Ala Ala Gly Lys Thr Cys Asn Gln Thr Thr Gly Gln Cys Pro 
385                 390                 395                 400 


Cys Lys Asp Gly Val Thr Gly Ile Thr Cys Asn Arg Cys Ala Lys Gly 
                405                 410                 415     


Tyr Gln Gln Ser Arg Ser Pro Ile Ala Pro Cys Ile Lys Ile Pro Val 
            420                 425                 430         


Ala Pro Pro Thr Thr Ala Ala Ser Ser Val Glu Glu Pro Glu Asp Cys 
        435                 440                 445             


Asp Ser Tyr Cys Lys Ala Ser Lys Gly Lys Leu Lys Ile Asn Met Lys 
    450                 455                 460                 


Lys Tyr Cys Lys Lys Asp Tyr Ala Val Gln Ile His Ile Leu Lys Ala 
465                 470                 475                 480 


Asp Lys Ala Gly Asp Trp Trp Lys Phe Thr Val Asn Ile Ile Ser Val 
                485                 490                 495     


Tyr Lys Gln Gly Thr Ser Arg Ile Arg Arg Gly Asp Gln Ser Leu Trp 
            500                 505                 510         


Ile Arg Ser Arg Asp Ile Ala Cys Lys Cys Pro Lys Ile Lys Pro Leu 
        515                 520                 525             


Lys Lys Tyr Leu Leu Leu Gly Asn Ala Glu Asp Ser Pro Asp Gln Ser 
    530                 535                 540                 


Gly Ile Val Ala Asp Lys Ser Ser Leu Val Ile Gln Trp Arg Asp Thr 
545                 550                 555                 560 


Trp Ala Arg Arg Leu Arg Lys Phe Gln Gln Arg Glu Lys Lys Gly Lys 
                565                 570                 575     


Cys Lys Lys Ala 
            580 


<210>  1017
<211>  553
<212>  PRT
<213>  Homo Sapiens

<400>  1017

Asp Pro Cys His Asp Glu Gly Gly Ala Pro Arg Gly Cys Val Pro Gly 
1               5                   10                  15      


Leu Val Asn Ala Ala Leu Gly Arg Glu Val Leu Ala Ser Ser Thr Cys 
            20                  25                  30          


Gly Arg Pro Ala Thr Arg Ala Cys Asp Ala Ser Asp Pro Arg Arg Ala 
        35                  40                  45              


His Ser Pro Ala Leu Leu Thr Ser Pro Gly Gly Thr Ala Ser Pro Leu 
    50                  55                  60                  


Cys Trp Arg Ser Glu Ser Leu Pro Arg Ala Pro Leu Asn Val Thr Leu 
65                  70                  75                  80  


Thr Val Pro Leu Gly Lys Ala Phe Glu Leu Val Phe Val Ser Leu Arg 
                85                  90                  95      


Phe Cys Ser Ala Pro Pro Ala Ser Val Ala Leu Leu Lys Ser Gln Asp 
            100                 105                 110         


His Gly Arg Ser Trp Ala Pro Leu Gly Phe Phe Ser Ser His Cys Asp 
        115                 120                 125             


Leu Asp Tyr Gly Arg Leu Pro Ala Pro Ala Asn Gly Pro Ala Gly Pro 
    130                 135                 140                 


Gly Pro Glu Ala Leu Cys Phe Pro Ala Pro Leu Ala Gln Pro Asp Gly 
145                 150                 155                 160 


Ser Gly Leu Leu Ala Phe Ser Met Gln Asp Ser Ser Pro Pro Gly Leu 
                165                 170                 175     


Asp Leu Asp Ser Ser Pro Val Leu Gln Asp Trp Val Thr Ala Thr Asp 
            180                 185                 190         


Val Arg Val Val Leu Thr Arg Pro Ser Thr Ala Gly Asp Pro Arg Asp 
        195                 200                 205             


Met Glu Ala Val Val Pro Tyr Ser Tyr Ala Ala Thr Asp Leu Gln Val 
    210                 215                 220                 


Gly Gly Arg Cys Lys Cys Asn Gly His Ala Ser Arg Cys Leu Leu Asp 
225                 230                 235                 240 


Thr Gln Gly His Leu Ile Cys Asp Cys Arg His Gly Thr Glu Gly Pro 
                245                 250                 255     


Asp Cys Gly Arg Cys Lys Pro Phe Tyr Cys Asp Arg Pro Trp Gln Arg 
            260                 265                 270         


Ala Thr Ala Arg Glu Ser His Ala Cys Leu Ala Cys Ser Cys Asn Gly 
        275                 280                 285             


His Ala Arg Arg Cys Arg Phe Asn Met Glu Leu Tyr Arg Leu Ser Gly 
    290                 295                 300                 


Arg Arg Ser Gly Gly Val Cys Leu Asn Cys Arg His Asn Thr Ala Gly 
305                 310                 315                 320 


Arg His Cys His Tyr Cys Arg Glu Gly Phe Tyr Arg Asp Pro Gly Arg 
                325                 330                 335     


Ala Leu Ser Asp Arg Arg Ala Cys Arg Ala Cys Asp Cys His Pro Val 
            340                 345                 350         


Gly Ala Ala Gly Lys Thr Cys Asn Gln Thr Thr Gly Gln Cys Pro Cys 
        355                 360                 365             


Lys Asp Gly Val Thr Gly Leu Thr Cys Asn Arg Cys Ala Pro Gly Phe 
    370                 375                 380                 


Gln Gln Ser Arg Ser Pro Val Ala Pro Cys Val Lys Thr Pro Ile Pro 
385                 390                 395                 400 


Gly Pro Thr Glu Asp Ser Ser Pro Val Gln Pro Gln Asp Cys Asp Ser 
                405                 410                 415     


His Cys Lys Pro Ala Arg Gly Ser Tyr Arg Ile Ser Leu Lys Lys Phe 
            420                 425                 430         


Cys Lys Lys Asp Tyr Ala Val Gln Val Ala Val Gly Ala Arg Gly Glu 
        435                 440                 445             


Ala Arg Gly Ala Trp Thr Arg Phe Pro Val Ala Val Leu Ala Val Phe 
    450                 455                 460                 


Arg Ser Gly Glu Glu Arg Ala Arg Arg Gly Ser Ser Ala Leu Trp Val 
465                 470                 475                 480 


Pro Ala Gly Asp Ala Ala Cys Gly Cys Pro Arg Leu Leu Pro Gly Arg 
                485                 490                 495     


Arg Tyr Leu Leu Leu Gly Gly Gly Pro Gly Ala Ala Ala Gly Gly Ala 
            500                 505                 510         


Gly Gly Arg Gly Pro Gly Leu Ile Ala Ala Arg Gly Ser Leu Val Leu 
        515                 520                 525             


Pro Trp Arg Asp Ala Trp Thr Arg Arg Leu Arg Arg Leu Gln Arg Arg 
    530                 535                 540                 


Glu Arg Arg Gly Arg Cys Ser Ala Ala 
545                 550             


<210>  1018
<211>  610
<212>  PRT
<213>  Homo Sapiens

<400>  1018

Gly Leu Ser Gly Val Ala Gly Val Ser Ser Arg Cys Glu Lys Ala Cys 
1               5                   10                  15      


Asn Pro Arg Met Gly Asn Leu Ala Leu Gly Arg Lys Leu Trp Ala Asp 
            20                  25                  30          


Thr Thr Cys Gly Gln Asn Ala Thr Glu Leu Tyr Cys Phe Tyr Ser Glu 
        35                  40                  45              


Asn Thr Asp Leu Thr Cys Arg Gln Pro Lys Cys Asp Lys Cys Asn Ala 
    50                  55                  60                  


Ala Tyr Pro His Leu Ala His Leu Pro Ser Ala Met Ala Asp Ser Ser 
65                  70                  75                  80  


Phe Arg Phe Pro Arg Thr Trp Trp Gln Ser Ala Glu Asp Val His Arg 
                85                  90                  95      


Glu Lys Ile Gln Leu Asp Leu Glu Ala Glu Phe Tyr Phe Thr His Leu 
            100                 105                 110         


Ile Val Met Phe Lys Ser Pro Arg Pro Ala Ala Met Val Leu Asp Arg 
        115                 120                 125             


Ser Gln Asp Phe Gly Lys Thr Trp Lys Pro Tyr Lys Tyr Phe Ala Thr 
    130                 135                 140                 


Asn Cys Ser Ala Thr Phe Gly Leu Glu Asp Asp Val Val Lys Lys Gly 
145                 150                 155                 160 


Ala Ile Cys Thr Ser Lys Tyr Ser Ser Pro Phe Pro Cys Thr Gly Gly 
                165                 170                 175     


Glu Val Ile Phe Lys Ala Leu Ser Pro Pro Tyr Asp Thr Glu Asn Pro 
            180                 185                 190         


Tyr Ser Ala Lys Val Gln Glu Gln Leu Lys Ile Thr Asn Leu Arg Val 
        195                 200                 205             


Gln Leu Leu Lys Arg Gln Ser Cys Pro Cys Gln Arg Asn Asp Leu Asn 
    210                 215                 220                 


Glu Glu Pro Gln His Phe Thr His Tyr Ala Ile Tyr Asp Phe Ile Val 
225                 230                 235                 240 


Lys Gly Ser Cys Phe Cys Asn Gly His Ala Asp Gln Cys Ile Pro Val 
                245                 250                 255     


His Gly Phe Arg Pro Val Lys Ala Pro Gly Thr Phe His Met Val His 
            260                 265                 270         


Gly Lys Cys Met Cys Lys His Asn Thr Ala Gly Ser His Cys Gln His 
        275                 280                 285             


Cys Ala Pro Leu Tyr Asn Asp Arg Pro Trp Glu Ala Ala Asp Gly Lys 
    290                 295                 300                 


Thr Gly Ala Pro Asn Glu Cys Arg Thr Cys Lys Cys Asn Gly His Ala 
305                 310                 315                 320 


Asp Thr Cys His Phe Asp Val Asn Val Trp Glu Ala Ser Gly Asn Arg 
                325                 330                 335     


Ser Gly Gly Val Cys Asp Asp Cys Gln His Asn Thr Glu Gly Gln Tyr 
            340                 345                 350         


Cys Gln Arg Cys Lys Pro Gly Phe Tyr Arg Asp Leu Arg Arg Pro Phe 
        355                 360                 365             


Ser Ala Pro Asp Ala Cys Lys Pro Cys Ser Cys His Pro Val Gly Ser 
    370                 375                 380                 


Ala Val Leu Pro Ala Asn Ser Val Thr Phe Cys Asp Pro Ser Asn Gly 
385                 390                 395                 400 


Asp Cys Pro Cys Lys Pro Gly Val Ala Gly Arg Arg Cys Asp Arg Cys 
                405                 410                 415     


Met Val Gly Tyr Trp Gly Phe Gly Asp Tyr Gly Cys Arg Pro Cys Asp 
            420                 425                 430         


Cys Ala Gly Ser Cys Asp Pro Ile Thr Gly Asp Cys Ile Ser Ser His 
        435                 440                 445             


Thr Asp Ile Asp Trp Tyr His Glu Val Pro Asp Phe Arg Pro Val His 
    450                 455                 460                 


Asn Lys Ser Glu Pro Ala Trp Glu Trp Glu Asp Ala Gln Gly Phe Ser 
465                 470                 475                 480 


Ala Leu Leu His Ser Gly Lys Cys Glu Cys Lys Glu Gln Thr Leu Gly 
                485                 490                 495     


Asn Ala Lys Ala Phe Cys Gly Met Lys Tyr Ser Tyr Val Leu Lys Ile 
            500                 505                 510         


Lys Ile Leu Ser Ala His Asp Lys Gly Thr His Val Glu Val Asn Val 
        515                 520                 525             


Lys Ile Lys Lys Val Leu Lys Ser Thr Lys Leu Lys Ile Phe Arg Gly 
    530                 535                 540                 


Lys Arg Thr Leu Tyr Pro Glu Ser Trp Thr Asp Arg Gly Cys Thr Cys 
545                 550                 555                 560 


Pro Ile Leu Asn Pro Gly Leu Glu Tyr Leu Val Ala Gly His Glu Asp 
                565                 570                 575     


Ile Arg Thr Gly Lys Leu Ile Val Asn Met Lys Ser Phe Val Gln His 
            580                 585                 590         


Trp Lys Pro Ser Leu Gly Arg Lys Val Met Asp Ile Leu Lys Arg Glu 
        595                 600                 605             


Cys Lys 
    610 


<210>  1019
<211>  473
<212>  PRT
<213>  Homo Sapiens

<400>  1019

Asp Pro Cys Tyr Asp Pro Gln Gly Arg Pro Gln Phe Cys Leu Pro Pro 
1               5                   10                  15      


Val Thr Gln Leu Ala Ala Val Ala Ala Ser Cys Pro Gln Ala Cys Ala 
            20                  25                  30          


Leu Ser Pro Gly Asn His Leu Gly Ala Arg Glu Thr Cys Asn Gly Ser 
        35                  40                  45              


Leu Thr Leu Ala Leu Gly Gly Pro Phe Leu Leu Thr Ser Val Ser Leu 
    50                  55                  60                  


Arg Phe Cys Thr Pro Gly Pro Pro Ala Leu Ile Leu Ser Ala Ala Trp 
65                  70                  75                  80  


Ala Ser Gly Gly Pro Trp Arg Leu Leu Trp His Arg Pro Ala Trp Pro 
                85                  90                  95      


Gly Ala Leu Gly Gly Pro Glu Arg Val Thr Phe His Ser Thr Pro Gly 
            100                 105                 110         


Pro Lys Ala Thr Val Ala Ala Ser His Leu Arg Val Glu Phe Gly Gly 
        115                 120                 125             


Gln Ala Gly Leu Ala Ala Ala Gly Leu Arg Gly Arg Cys Gln Cys His 
    130                 135                 140                 


Gly His Ala Ala Arg Cys Ala Ala Arg Ala Arg Pro Pro Arg Cys His 
145                 150                 155                 160 


Cys Arg His His Thr Thr Gly Pro Gly Cys Glu Ser Cys Arg Pro Ser 
                165                 170                 175     


His Arg Asp Trp Pro Trp Arg Pro Ala Thr Pro Arg His Pro His Pro 
            180                 185                 190         


Cys Leu Pro Cys Ser Cys Asn Gln His Ala Arg Arg Cys Arg Phe Asn 
        195                 200                 205             


Ser Glu Leu Phe Arg Leu Ser Gly Gly Arg Ser Gly Gly Val Cys Glu 
    210                 215                 220                 


Arg Cys Arg His His Thr Ala Gly Arg His Cys His Tyr Cys Gln Pro 
225                 230                 235                 240 


Gly Phe Trp Arg Asp Pro Ser Gln Pro Ile Phe Ser Arg Arg Ala Cys 
                245                 250                 255     


Arg Ala Cys Gln Cys His Pro Ile Gly Ala Thr Gly Gly Thr Cys Asn 
            260                 265                 270         


Gln Thr Ser Gly Gln Cys Thr Cys Lys Leu Gly Val Thr Gly Leu Thr 
        275                 280                 285             


Cys Asn Arg Cys Gly Pro Gly Tyr Gln Gln Ser Arg Ser Pro Arg Met 
    290                 295                 300                 


Pro Cys Gln Arg Ile Pro Glu Ala Thr Thr Thr Leu Ala Thr Thr Pro 
305                 310                 315                 320 


Gly Ala Tyr Ser Ser Asp Pro Gln Cys Gln Asn Tyr Cys Asn Met Ser 
                325                 330                 335     


Asp Thr Arg Val His Met Ser Leu Arg Arg Tyr Cys Gln Gln Asp His 
            340                 345                 350         


Val Leu Arg Ala Gln Val Leu Ala Ser Glu Ala Ala Gly Pro Ala Trp 
        355                 360                 365             


Gln Arg Leu Ala Val Arg Val Leu Ala Val Tyr Lys Gln Arg Ala Gln 
    370                 375                 380                 


Pro Val Arg Arg Gly Asp Gln Asp Ala Trp Val Pro Arg Ala Asp Leu 
385                 390                 395                 400 


Thr Cys Gly Cys Leu Arg Leu Gln Pro Gly Thr Asp Tyr Leu Leu Leu 
                405                 410                 415     


Gly Ser Ala Val Gly Asp Pro Asp Pro Thr Arg Leu Ile Leu Asp Arg 
            420                 425                 430         


His Gly Leu Ala Leu Pro Trp Arg Pro Arg Trp Ala Arg Pro Leu Lys 
        435                 440                 445             


Arg Leu Gln Gln Glu Glu Arg Ala Gly Gly Cys Arg Gly Val Arg Ala 
    450                 455                 460                 


Pro Thr Pro Ser Pro Arg Pro Glu His 
465                 470             


<210>  1020
<211>  381
<212>  PRT
<213>  Homo Sapiens

<400>  1020

His Tyr Asp Leu Cys Lys Thr Gln Ile Tyr Thr Glu Glu Gly Lys Val 
1               5                   10                  15      


Trp Asp Tyr Met Ala Cys Gln Pro Glu Ser Thr Asp Met Thr Lys Tyr 
            20                  25                  30          


Leu Lys Val Lys Leu Asp Pro Pro Asp Ile Thr Cys Gly Asp Pro Pro 
        35                  40                  45              


Glu Thr Phe Cys Ala Met Gly Asn Pro Tyr Met Cys Asn Asn Glu Cys 
    50                  55                  60                  


Asp Ala Ser Thr Pro Glu Leu Ala His Pro Pro Glu Leu Met Phe Asp 
65                  70                  75                  80  


Phe Glu Gly Arg His Pro Ser Thr Phe Trp Gln Ser Ala Thr Trp Lys 
                85                  90                  95      


Glu Tyr Pro Lys Pro Leu Gln Val Asn Ile Thr Leu Ser Trp Ser Lys 
            100                 105                 110         


Thr Ile Glu Leu Thr Asp Asn Ile Val Ile Thr Phe Glu Ser Gly Arg 
        115                 120                 125             


Pro Asp Gln Met Ile Leu Glu Lys Ser Leu Asp Tyr Gly Arg Thr Trp 
    130                 135                 140                 


Gln Pro Tyr Gln Tyr Tyr Ala Thr Asp Cys Leu Asp Ala Phe His Met 
145                 150                 155                 160 


Asp Pro Lys Ser Val Lys Asp Leu Ser Gln His Thr Val Leu Glu Ile 
                165                 170                 175     


Ile Cys Thr Glu Glu Tyr Ser Thr Gly Tyr Thr Thr Asn Ser Lys Ile 
            180                 185                 190         


Ile His Phe Glu Ile Lys Asp Arg Phe Ala Phe Phe Ala Gly Pro Arg 
        195                 200                 205             


Leu Arg Asn Met Ala Ser Leu Tyr Gly Gln Leu Asp Thr Thr Lys Lys 
    210                 215                 220                 


Leu Arg Asp Phe Phe Thr Val Thr Asp Leu Arg Ile Arg Leu Leu Arg 
225                 230                 235                 240 


Pro Ala Val Gly Glu Ile Phe Val Asp Glu Leu His Leu Ala Arg Tyr 
                245                 250                 255     


Phe Tyr Ala Ile Ser Asp Ile Lys Val Arg Gly Arg Cys Lys Cys Asn 
            260                 265                 270         


Leu His Ala Thr Val Cys Val Tyr Asp Asn Ser Lys Leu Thr Cys Glu 
        275                 280                 285             


Cys Glu His Asn Thr Thr Gly Pro Asp Cys Gly Lys Cys Lys Lys Asn 
    290                 295                 300                 


Tyr Gln Gly Arg Pro Trp Ser Pro Gly Ser Tyr Leu Pro Ile Pro Lys 
305                 310                 315                 320 


Gly Thr Ala Asn Thr Cys Ile Pro Ser Ile Ser Ser Ile Gly Thr Asn 
                325                 330                 335     


Val Cys Asp Asn Glu Leu Leu His Cys Gln Asn Gly Gly Thr Cys His 
            340                 345                 350         


Asn Asn Val Arg Cys Leu Cys Pro Ala Ala Tyr Thr Gly Ile Leu Cys 
        355                 360                 365             


Glu Lys Leu Arg Cys Glu Glu Ala Gly Ser Cys Gly Ser 
    370                 375                 380     


<210>  1021
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  1021

Asp Tyr Asp Ile Cys Lys Ser Trp Val Thr Thr Asp Glu Gly Pro Thr 
1               5                   10                  15      


Trp Glu Phe Tyr Ala Cys Gln Pro Lys Val Met Arg Leu Lys Asp Tyr 
            20                  25                  30          


Val Lys Val Lys Val Glu Pro Ser Gly Ile Thr Cys Gly Asp Pro Pro 
        35                  40                  45              


Glu Arg Phe Cys Ser His Glu Asn Pro Tyr Leu Cys Ser Asn Glu Cys 
    50                  55                  60                  


Asp Ala Ser Asn Pro Asp Leu Ala His Pro Pro Arg Leu Met Phe Asp 
65                  70                  75                  80  


Lys Glu Glu Glu Gly Leu Ala Thr Tyr Trp Gln Ser Ile Thr Trp Ser 
                85                  90                  95      


Arg Tyr Pro Ser Pro Leu Glu Ala Asn Ile Thr Leu Ser Trp Asn Lys 
            100                 105                 110         


Thr Val Glu Leu Thr Asp Asp Val Val Met Thr Phe Glu Tyr Gly Arg 
        115                 120                 125             


Pro Thr Val Met Val Leu Glu Lys Ser Leu Asp Asn Gly Arg Thr Trp 
    130                 135                 140                 


Gln Pro Tyr Gln Phe Tyr Ala Glu Asp Cys Met Glu Ala Phe Gly Met 
145                 150                 155                 160 


Ser Ala Arg Arg Ala Arg Asp Met Ser Ser Ser Ser Ala His Arg Val 
                165                 170                 175     


Leu Cys Thr Glu Glu Tyr Ser Arg Trp Ala Gly Ser Lys Lys Glu Lys 
            180                 185                 190         


His Val Arg Phe Glu Val Arg Asp Arg Phe Ala Ile Phe Ala Gly Pro 
        195                 200                 205             


Asp Leu Arg Asn Met Asp Asn Leu Tyr Thr Arg Leu Glu Ser Ala Lys 
    210                 215                 220                 


Gly Leu Lys Glu Phe Phe Thr Leu Thr Asp Leu Arg Met Arg Leu Leu 
225                 230                 235                 240 


Arg Pro Ala Leu Gly Gly Thr Tyr Val Gln Arg Glu Asn Leu Tyr Lys 
                245                 250                 255     


Tyr Phe Tyr Ala Ile Ser Asn Ile Glu Val Ile Gly Arg Cys Lys Cys 
            260                 265                 270         


Asn Leu His Ala Asn Leu Cys Ser Met Arg Glu Gly Ser Leu Gln Cys 
        275                 280                 285             


Glu Cys Glu His Asn Thr Thr Gly Pro Asp Cys Gly Lys Cys Lys Lys 
    290                 295                 300                 


Asn Phe Arg Thr Arg Ser Trp Arg Ala Gly Ser Tyr Leu Pro Leu Pro 
305                 310                 315                 320 


His Gly Ser Pro Asn Ala Cys Ala Ala Ala Gly Ser Phe Gly Asn Cys 
                325                 330                 335     


Glu Cys Tyr Gly His Ser Asn Arg Cys Ser Tyr Ile Asp Phe Leu Asn 
            340                 345                 350         


Val Val Thr Cys Val Ser Cys Lys His Asn Thr Arg Gly Gln His Cys 
        355                 360                 365             


Gln His Cys Arg Leu Gly Tyr Tyr Arg Asn Gly Ser Ala Glu Leu Asp 
    370                 375                 380                 


Asp Glu Asn Val Cys Ile Glu Cys Asn Cys Asn Gln Ile Gly Ser Val 
385                 390                 395                 400 


His Asp Arg Cys Asn Glu Thr Gly Phe Cys Glu Cys Arg Glu Gly Ala 
                405                 410                 415     


Ala Gly Pro Lys Cys Asp Asp Cys Leu Pro Thr His Tyr Trp Arg Gln 
            420                 425                 430         


Gly Cys Tyr Pro Asn Val Cys Asp Asp Asp Gln Leu Leu Cys Gln Asn 
        435                 440                 445             


Gly Gly Thr Cys Leu Gln Asn Gln Arg Cys Ala Cys Pro Arg Gly Tyr 
    450                 455                 460                 


Thr Gly Val Arg Cys Glu Gln Pro Arg Cys Asp Pro Ala Asp Asp Asp 
465                 470                 475                 480 


Gly Gly Leu Asp Cys Asp Arg Ala Pro Gly 
                485                 490 


<210>  1022
<211>  391
<212>  PRT
<213>  Homo Sapiens

<400>  1022

Ala Ala Pro Cys Pro Asp Ala Cys Cys Pro His Gly Ser Ser Gly Leu 
1               5                   10                  15      


Arg Cys Thr Arg Asp Gly Ala Leu Asp Ser Leu His His Leu Pro Gly 
            20                  25                  30          


Ala Glu Asn Leu Thr Glu Leu Tyr Ile Glu Asn Gln Gln His Leu Gln 
        35                  40                  45              


His Leu Glu Leu Arg Asp Leu Arg Gly Leu Gly Glu Leu Arg Asn Leu 
    50                  55                  60                  


Thr Ile Val Lys Ser Gly Leu Arg Phe Val Ala Pro Asp Ala Phe His 
65                  70                  75                  80  


Phe Thr Pro Arg Leu Ser Arg Leu Asn Leu Ser Phe Asn Ala Leu Glu 
                85                  90                  95      


Ser Leu Ser Trp Lys Thr Val Gln Gly Leu Ser Leu Gln Glu Leu Val 
            100                 105                 110         


Leu Ser Gly Asn Pro Leu His Cys Ser Cys Ala Leu Arg Trp Leu Gln 
        115                 120                 125             


Arg Trp Glu Glu Glu Gly Leu Gly Gly Val Pro Glu Gln Lys Leu Gln 
    130                 135                 140                 


Cys His Gly Gln Gly Pro Leu Ala His Met Pro Asn Ala Ser Cys Gly 
145                 150                 155                 160 


Val Pro Thr Leu Lys Val Gln Val Pro Asn Ala Ser Val Asp Val Gly 
                165                 170                 175     


Asp Asp Val Leu Leu Arg Cys Gln Val Glu Gly Arg Gly Leu Glu Gln 
            180                 185                 190         


Ala Gly Trp Ile Leu Thr Glu Leu Glu Gln Ser Ala Thr Val Met Lys 
        195                 200                 205             


Ser Gly Gly Leu Pro Ser Leu Gly Leu Thr Leu Ala Asn Val Thr Ser 
    210                 215                 220                 


Asp Leu Asn Arg Lys Asn Val Thr Cys Trp Ala Glu Asn Asp Val Gly 
225                 230                 235                 240 


Arg Ala Glu Val Ser Val Gln Val Asn Val Ser Phe Pro Ala Ser Val 
                245                 250                 255     


Gln Leu His Thr Ala Val Glu Met His His Trp Cys Ile Pro Phe Ser 
            260                 265                 270         


Val Asp Gly Gln Pro Ala Pro Ser Leu Arg Trp Leu Phe Asn Gly Ser 
        275                 280                 285             


Val Leu Asn Glu Thr Ser Phe Ile Phe Thr Glu Phe Leu Glu Pro Ala 
    290                 295                 300                 


Ala Asn Glu Thr Val Arg His Gly Cys Leu Arg Leu Asn Gln Pro Thr 
305                 310                 315                 320 


His Val Asn Asn Gly Asn Tyr Thr Leu Leu Ala Ala Asn Pro Phe Gly 
                325                 330                 335     


Gln Ala Ser Ala Ser Ile Met Ala Ala Phe Met Asp Asn Pro Phe Glu 
            340                 345                 350         


Phe Asn Pro Glu Asp Pro Ile Pro Val Ser Phe Ser Pro Val Asp Thr 
        355                 360                 365             


Asn Ser Thr Ser Gly Asp Pro Val Glu Lys Lys Asp Glu Thr Pro Phe 
    370                 375                 380                 


Gly Val Ser Val Ala Val Gly 
385                 390     


<210>  1023
<211>  399
<212>  PRT
<213>  Homo Sapiens

<400>  1023

Cys Pro Thr Ser Cys Lys Cys Ser Ala Ser Arg Ile Trp Cys Ser Asp 
1               5                   10                  15      


Pro Ser Pro Gly Ile Val Ala Phe Pro Arg Leu Glu Pro Asn Ser Val 
            20                  25                  30          


Asp Pro Glu Asn Ile Thr Glu Ile Phe Ile Ala Asn Gln Lys Arg Leu 
        35                  40                  45              


Glu Ile Ile Asn Glu Asp Asp Val Glu Ala Tyr Val Gly Leu Arg Asn 
    50                  55                  60                  


Leu Thr Ile Val Asp Ser Gly Leu Lys Phe Val Ala His Lys Ala Phe 
65                  70                  75                  80  


Leu Lys Asn Ser Asn Leu Gln His Ile Asn Phe Thr Arg Asn Lys Leu 
                85                  90                  95      


Thr Ser Leu Ser Arg Lys His Phe Arg His Leu Asp Leu Ser Glu Leu 
            100                 105                 110         


Ile Leu Val Gly Asn Pro Phe Thr Cys Ser Cys Asp Ile Met Trp Ile 
        115                 120                 125             


Lys Thr Leu Gln Glu Ala Lys Ser Ser Pro Asp Thr Gln Asp Leu Tyr 
    130                 135                 140                 


Cys Leu Asn Glu Ser Ser Lys Asn Ile Pro Leu Ala Asn Leu Gln Ile 
145                 150                 155                 160 


Pro Asn Cys Gly Leu Pro Ser Ala Asn Leu Ala Ala Pro Asn Leu Thr 
                165                 170                 175     


Val Glu Glu Gly Lys Ser Ile Thr Leu Ser Cys Ser Val Ala Gly Asp 
            180                 185                 190         


Pro Val Pro Asn Met Tyr Trp Asp Val Gly Asn Leu Val Ser Lys His 
        195                 200                 205             


Met Asn Glu Thr Ser His Thr Gln Gly Ser Leu Arg Ile Thr Asn Ile 
    210                 215                 220                 


Ser Ser Asp Asp Ser Gly Lys Gln Ile Ser Cys Val Ala Glu Asn Leu 
225                 230                 235                 240 


Val Gly Glu Asp Gln Asp Ser Val Asn Leu Thr Val His Phe Ala Pro 
                245                 250                 255     


Thr Ile Thr Phe Leu Glu Ser Pro Thr Ser Asp His His Trp Cys Ile 
            260                 265                 270         


Pro Phe Thr Val Lys Gly Asn Pro Lys Pro Ala Leu Gln Trp Phe Tyr 
        275                 280                 285             


Asn Gly Ala Ile Leu Asn Glu Ser Lys Tyr Ile Cys Thr Lys Ile His 
    290                 295                 300                 


Val Thr Asn His Thr Glu Tyr His Gly Cys Leu Gln Leu Asp Asn Pro 
305                 310                 315                 320 


Thr His Met Asn Asn Gly Asp Tyr Thr Leu Ile Ala Lys Asn Glu Tyr 
                325                 330                 335     


Gly Lys Asp Glu Lys Gln Ile Ser Ala His Phe Met Gly Trp Pro Gly 
            340                 345                 350         


Ile Asp Asp Gly Ala Asn Pro Asn Tyr Pro Asp Val Ile Tyr Glu Asp 
        355                 360                 365             


Tyr Gly Thr Ala Ala Asn Asp Ile Gly Asp Thr Thr Asn Arg Ser Asn 
    370                 375                 380                 


Glu Ile Pro Ser Thr Asp Val Thr Asp Lys Thr Gly Arg Glu His 
385                 390                 395                 


<210>  1024
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  1024

Cys Pro Ala Asn Cys Val Cys Ser Lys Thr Glu Ile Asn Cys Arg Arg 
1               5                   10                  15      


Pro Asp Asp Gly Asn Leu Phe Pro Leu Leu Glu Gly Gln Asp Ser Gly 
            20                  25                  30          


Asn Ser Asn Gly Asn Ala Ser Ile Asn Ile Thr Asp Ile Ser Arg Asn 
        35                  40                  45              


Ile Thr Ser Ile His Ile Glu Asn Trp Arg Ser Leu His Thr Leu Asn 
    50                  55                  60                  


Ala Val Asp Met Glu Leu Tyr Thr Gly Leu Gln Lys Leu Thr Ile Lys 
65                  70                  75                  80  


Asn Ser Gly Leu Arg Ser Ile Gln Pro Arg Ala Phe Ala Lys Asn Pro 
                85                  90                  95      


His Leu Arg Tyr Ile Asn Leu Ser Ser Asn Arg Leu Thr Thr Leu Ser 
            100                 105                 110         


Trp Gln Leu Phe Gln Thr Leu Ser Leu Arg Glu Leu Gln Leu Glu Gln 
        115                 120                 125             


Asn Phe Phe Asn Cys Ser Cys Asp Ile Arg Trp Met Gln Leu Trp Gln 
    130                 135                 140                 


Glu Gln Gly Glu Ala Lys Leu Asn Ser Gln Asn Leu Tyr Cys Ile Asn 
145                 150                 155                 160 


Ala Asp Gly Ser Gln Leu Pro Leu Phe Arg Met Asn Ile Ser Gln Cys 
                165                 170                 175     


Asp Leu Pro Glu Ile Ser Val Ser His Val Asn Leu Thr Val Arg Glu 
            180                 185                 190         


Gly Asp Asn Ala Val Ile Thr Cys Asn Gly Ser Gly Ser Pro Leu Pro 
        195                 200                 205             


Asp Val Asp Trp Ile Val Thr Gly Leu Gln Ser Ile Asn Thr His Gln 
    210                 215                 220                 


Thr Asn Leu Asn Trp Thr Asn Val His Ala Ile Asn Leu Thr Leu Val 
225                 230                 235                 240 


Asn Val Thr Ser Glu Asp Asn Gly Phe Thr Leu Thr Cys Ile Ala Glu 
                245                 250                 255     


Asn Val Val Gly Met Ser Asn Ala Ser Val Ala Leu Thr Val Tyr Tyr 
            260                 265                 270         


Pro Pro Arg Val Val Ser Leu Glu Glu Pro Glu Leu Arg Leu Glu His 
        275                 280                 285             


Cys Ile Glu Phe Val Val Arg Gly Asn Pro Pro Pro Thr Leu His Trp 
    290                 295                 300                 


Leu His Asn Gly Gln Pro Leu Arg Glu Ser Lys Ile Ile His Val Glu 
305                 310                 315                 320 


Tyr Tyr Gln Glu Gly Glu Ile Ser Glu Gly Cys Leu Leu Phe Asn Lys 
                325                 330                 335     


Pro Thr His Tyr Asn Asn Gly Asn Tyr Thr Leu Ile Ala Lys Asn Pro 
            340                 345                 350         


Leu Gly Thr Ala Asn Gln Thr Ile Asn Gly His Phe Leu Lys Glu Pro 
        355                 360                 365             


Phe Pro Glu Ser Thr Asp Asn Phe Ile Leu Phe Asp Glu Val Ser Pro 
    370                 375                 380                 


Thr Pro Pro Ile Thr Val Thr His Lys Pro Glu Glu Asp Thr 
385                 390                 395             


<210>  1025
<211>  405
<212>  PRT
<213>  Homo Sapiens

<400>  1025

Met Ser Ser Pro Ala Leu Thr Ala Gly Ala Ser Gly Lys Val Met Asp 
1               5                   10                  15      


Phe Asn Asn Gly Thr Tyr Leu Val Ser Phe Thr Leu Phe Trp Glu Gly 
            20                  25                  30          


Gln Val Ser Leu Ser Leu Leu Leu Ile His Pro Ser Glu Gly Ala Ser 
        35                  40                  45              


Ala Leu Trp Arg Ala Arg Asn Gln Gly Tyr Asp Lys Ile Ile Phe Lys 
    50                  55                  60                  


Gly Lys Phe Val Asn Gly Thr Ser His Val Phe Thr Glu Cys Gly Leu 
65                  70                  75                  80  


Thr Leu Asn Ser Asn Ala Glu Leu Cys Glu Tyr Leu Asp Asp Arg Asp 
                85                  90                  95      


Gln Glu Ala Phe Tyr Cys Met Lys Pro Gln His Met Pro Cys Glu Ala 
            100                 105                 110         


Leu Thr Tyr Met Thr Thr Arg Asn Arg Glu Val Ser Tyr Leu Thr Asp 
        115                 120                 125             


Lys Glu Asn Ser Leu Phe His Arg Ser Lys Val Gly Val Glu Met Met 
    130                 135                 140                 


Lys Asp Arg Lys His Ile Asp Val Thr Asn Cys Asn Lys Arg Glu Lys 
145                 150                 155                 160 


Ile Glu Glu Thr Cys Gln Val Gly Met Lys Pro Pro Val Pro Gly Gly 
                165                 170                 175     


Tyr Thr Leu Gln Gly Lys Trp Ile Thr Thr Phe Cys Asn Gln Val Gln 
            180                 185                 190         


Leu Asp Thr Ile Lys Ile Asn Gly Cys Leu Lys Gly Lys Leu Ile Tyr 
        195                 200                 205             


Leu Leu Gly Asp Ser Thr Leu Arg Gln Trp Ile Tyr Tyr Phe Pro Lys 
    210                 215                 220                 


Val Val Lys Thr Leu Lys Phe Phe Asp Leu His Glu Thr Gly Ile Phe 
225                 230                 235                 240 


Lys Lys His Leu Leu Leu Asp Ala Glu Arg His Thr Gln Ile Gln Trp 
                245                 250                 255     


Lys Lys His Ser Tyr Pro Phe Val Thr Phe Gln Leu Tyr Ser Leu Ile 
            260                 265                 270         


Asp His Asp Tyr Ile Pro Arg Glu Ile Asp Arg Leu Ser Gly Asp Lys 
        275                 280                 285             


Asn Thr Ala Ile Val Ile Thr Phe Gly Gln His Phe Arg Pro Phe Pro 
    290                 295                 300                 


Ile Asp Ile Phe Ile Arg Arg Ala Ile Gly Val Gln Lys Ala Ile Glu 
305                 310                 315                 320 


Arg Leu Phe Leu Arg Ser Pro Ala Thr Lys Val Ile Ile Lys Thr Glu 
                325                 330                 335     


Asn Ile Arg Glu Met His Ile Glu Thr Glu Arg Phe Val Asp Phe His 
            340                 345                 350         


Gly Tyr Ile His Tyr Leu Ile Met Lys Asp Ile Phe Lys Asp Leu Asn 
        355                 360                 365             


Val Gly Ile Ile Asp Ala Trp Asp Met Thr Ile Ala Tyr Gly Thr Asp 
    370                 375                 380                 


Thr Ile His Pro Pro Asp His Val Ile Gly Asn Gln Ile Asn Met Phe 
385                 390                 395                 400 


Leu Asn Tyr Ile Cys 
                405 


<210>  1026
<211>  529
<212>  PRT
<213>  Homo Sapiens

<400>  1026

Glu Tyr Leu Asp His Glu Thr Val Ser Ala Thr Phe Ile Asp Ser Ser 
1               5                   10                  15      


Gly Gln Phe Val Ser Ser Gln Val Thr Gly Ile Ser Arg Asn Pro Tyr 
            20                  25                  30          


Cys Gly Tyr Asp Gln Gln Thr Leu Ser Ser Gln Glu Arg Met Glu Glu 
        35                  40                  45              


Asp Ser Leu Leu Ala Ala Leu His Arg Gln Val Pro Asp Val Gly Pro 
    50                  55                  60                  


Val Pro Phe Val Lys Ser Thr Asp Pro Ser Ser Ser Tyr Phe Val Ile 
65                  70                  75                  80  


Leu Asn Ser Ala Ala Phe Phe Lys Val Gly Ser Gln Leu Glu Val Leu 
                85                  90                  95      


Val His Val Gln Asp Phe Gln Arg Lys Pro Lys Lys Tyr Gly Gly Asp 
            100                 105                 110         


Tyr Leu Gln Ala Arg Ile His Ser Leu Lys Leu Gln Ala Gly Ala Val 
        115                 120                 125             


Gly Arg Val Val Asp Tyr Gln Asn Gly Phe Tyr Lys Val Phe Phe Thr 
    130                 135                 140                 


Leu Leu Trp Pro Gly Lys Val Lys Val Ser Val Ser Leu Val His Pro 
145                 150                 155                 160 


Ser Glu Gly Ile Arg Val Leu Gln Arg Leu Gln Glu Asp Lys Pro Asp 
                165                 170                 175     


Arg Val Tyr Phe Lys Ser Leu Phe Arg Ser Gly Arg Ile Ser Glu Thr 
            180                 185                 190         


Thr Glu Cys Asn Val Cys Leu Pro Gly Asn Leu Pro Leu Cys Asn Phe 
        195                 200                 205             


Thr Asp Leu Tyr Thr Gly Glu Pro Trp Phe Cys Phe Lys Pro Lys Lys 
    210                 215                 220                 


Leu Pro Cys Ser Ser Arg Ile Thr His Phe Lys Gly Gly Tyr Leu Lys 
225                 230                 235                 240 


Gly Leu Leu Thr Ala Ala Glu Ser Ala Phe Phe Gln Ser Gly Val Asn 
                245                 250                 255     


Ile Lys Met Pro Val Asn Ser Ser Gly Pro Asp Trp Val Thr Val Ile 
            260                 265                 270         


Pro Arg Arg Ile Lys Glu Thr Asn Ser Leu Glu Leu Ser Gln Gly Ser 
        275                 280                 285             


Gly Thr Phe Pro Ser Gly Tyr Tyr Tyr Lys Asp Gln Trp Arg Pro Arg 
    290                 295                 300                 


Lys Phe Lys Met Arg Gln Phe Asn Asp Pro Asp Asn Ile Thr Glu Cys 
305                 310                 315                 320 


Leu Gln Arg Lys Val Val His Leu Phe Gly Asp Ser Thr Ile Arg Gln 
                325                 330                 335     


Trp Phe Glu Tyr Leu Thr Thr Phe Val Pro Asp Leu Val Glu Phe Asn 
            340                 345                 350         


Leu Gly Ser Pro Lys Asn Val Gly Pro Phe Leu Ala Val Asp Gln Lys 
        355                 360                 365             


His Asn Ile Leu Leu Lys Tyr Arg Cys His Gly Pro Pro Ile Arg Phe 
    370                 375                 380                 


Thr Thr Val Phe Ser Asn Glu Leu His Tyr Val Ala Asn Glu Leu Asn 
385                 390                 395                 400 


Gly Ile Val Gly Gly Lys Asn Thr Val Val Ala Ile Ala Val Trp Ser 
                405                 410                 415     


His Phe Ser Thr Phe Pro Leu Glu Val Tyr Ile Arg Arg Leu Arg Asn 
            420                 425                 430         


Ile Arg Arg Ala Val Val Arg Leu Leu Asp Arg Ser Pro Lys Thr Val 
        435                 440                 445             


Val Val Ile Arg Thr Ala Asn Ala Gln Glu Leu Gly Pro Glu Val Ser 
    450                 455                 460                 


Leu Phe Asn Ser Asp Trp Tyr Asn Phe Gln Leu Asp Thr Ile Leu Arg 
465                 470                 475                 480 


Arg Met Phe Ser Gly Val Gly Val Tyr Leu Val Asp Ala Trp Glu Met 
                485                 490                 495     


Thr Leu Ala His Tyr Leu Pro His Lys Leu His Pro Asp Glu Val Ile 
            500                 505                 510         


Val Lys Asn Gln Leu Asp Met Phe Leu Ser Phe Val Cys Pro Leu Glu 
        515                 520                 525             


Thr 
    


<210>  1027
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  1027

Gln Asn Ser Thr Lys Val Trp Ser Ala Leu Asn Leu Ser Ile Ser Leu 
1               5                   10                  15      


His Tyr Trp Asn Asn Ser Thr Lys Ser Leu Phe Pro Lys Thr Pro Leu 
            20                  25                  30          


Ile Ser Leu Lys Pro Leu Thr Glu Thr Glu Leu Arg Ile Lys Glu Ile 
        35                  40                  45              


Ile Glu Lys Leu Asp Gln Gln Ile Pro Pro Arg Pro Phe Thr His Val 
    50                  55                  60                  


Asn Thr Thr Thr Ser Ala Thr His Ser Thr Ala Thr Ile Leu Asn Pro 
65                  70                  75                  80  


Arg Asp Thr Tyr Cys Arg Gly Asp Gln Leu His Ile Leu Leu Glu Val 
                85                  90                  95      


Arg Asp His Leu Gly Arg Arg Lys Gln Tyr Gly Gly Asp Phe Leu Arg 
            100                 105                 110         


Ala Arg Met Ser Ser Pro Ala Leu Met Ala Gly Ala Ser Gly Lys Val 
        115                 120                 125             


Thr Asp Phe Asn Asn Gly Thr Tyr Leu Val Ser Phe Thr Leu Phe Trp 
    130                 135                 140                 


Glu Gly Gln Val Ser Leu Ser Leu Leu Leu Ile His Pro Ser Glu Gly 
145                 150                 155                 160 


Val Ser Ala Leu Trp Ser Ala Arg Asn Gln Gly Tyr Asp Arg Val Ile 
                165                 170                 175     


Phe Thr Gly Gln Phe Val Asn Gly Thr Ser Gln Val His Ser Glu Cys 
            180                 185                 190         


Gly Leu Ile Leu Asn Thr Asn Ala Glu Leu Cys Gln Tyr Leu Asp Asn 
        195                 200                 205             


Arg Asp Gln Glu Gly Phe Tyr Cys Val Arg Pro Gln His Met Pro Cys 
    210                 215                 220                 


Ala Ala Leu Thr His Met Tyr Ser Lys Asn Lys Lys Val Ser Tyr Leu 
225                 230                 235                 240 


Ser Lys Gln Glu Lys Ser Leu Phe Glu Arg Ser Asn Val Gly Val Glu 
                245                 250                 255     


Ile Met Glu Lys Phe Asn Thr Ile Ser Val Ser Lys Cys Asn Lys Glu 
            260                 265                 270         


Thr Val Ala Met Lys Glu Lys Cys Lys Phe Gly Met Thr Ser Thr Ile 
        275                 280                 285             


Pro Ser Gly His Val Trp Arg Asn Thr Trp Asn Pro Val Ser Cys Ser 
    290                 295                 300                 


Leu Ala Thr Val Lys Met Lys Glu Cys Leu Arg Gly Lys Leu Ile Tyr 
305                 310                 315                 320 


Leu Met Gly Asp Ser Thr Ile Arg Gln Trp Met Glu Tyr Phe Lys Ala 
                325                 330                 335     


Ser Ile Asn Thr Leu Lys Ser Val Asp Leu His Glu Ser Gly Lys Leu 
            340                 345                 350         


Gln His Gln Leu Ala Val Asp Leu Asp Arg Asn Ile Asn Ile Gln Trp 
        355                 360                 365             


Gln Lys Tyr Cys Tyr Pro Leu Ile Gly Ser Met Thr Tyr Ser Val Lys 
    370                 375                 380                 


Glu Met Glu Tyr Leu Thr Arg Ala Ile Asp Arg Thr Gly Gly Glu Lys 
385                 390                 395                 400 


Asn Thr Val Ile Val Ile Ser Leu Gly Gln His Phe Arg Pro Phe Pro 
                405                 410                 415     


Ile Asp Val Phe Ile Arg Arg Ala Leu Asn Val His Lys Ala Ile Gln 
            420                 425                 430         


His Leu Leu Leu Arg Ser Pro Asp Thr Met Val Ile Ile Lys Thr Glu 
        435                 440                 445             


Asn Ile Arg Glu Met Tyr Asn Asp Ala Glu Arg Phe Ser Asp Phe His 
    450                 455                 460                 


Gly Tyr Ile Gln Tyr Leu Ile Ile Lys Asp Ile Phe Gln Asp Leu Ser 
465                 470                 475                 480 


Val Ser Ile Ile Asp Ala Trp Asp Ile Thr Ile Ala Tyr Gly Thr Asn 
                485                 490                 495     


Asn Val His Pro Pro Gln His Val Val Gly Asn Gln Ile Asn Ile Leu 
            500                 505                 510         


Leu Asn Tyr Ile Cys 
        515         


<210>  1028
<211>  458
<212>  PRT
<213>  Homo Sapiens

<400>  1028

Val Gly Ala Cys Ala Arg Ala Cys Pro Ala Ala Cys Ala Cys Ser Thr 
1               5                   10                  15      


Val Glu Arg Gly Cys Ser Val Arg Cys Asp Arg Ala Gly Leu Leu Arg 
            20                  25                  30          


Val Pro Ala Glu Leu Pro Cys Glu Ala Val Ser Ile Asp Leu Asp Arg 
        35                  40                  45              


Asn Gly Leu Arg Phe Leu Gly Glu Arg Ala Phe Gly Thr Leu Pro Ser 
    50                  55                  60                  


Leu Arg Arg Leu Ser Leu Arg His Asn Asn Leu Ser Phe Ile Thr Pro 
65                  70                  75                  80  


Gly Ala Phe Lys Gly Leu Pro Arg Leu Ala Glu Leu Arg Leu Ala His 
                85                  90                  95      


Asn Gly Asp Leu Arg Tyr Leu His Ala Arg Thr Phe Ala Ala Leu Ser 
            100                 105                 110         


Arg Leu Arg Arg Leu Asp Leu Ala Ala Cys Arg Leu Phe Ser Val Pro 
        115                 120                 125             


Glu Arg Leu Leu Ala Glu Leu Pro Ala Leu Arg Glu Leu Ala Ala Phe 
    130                 135                 140                 


Asp Asn Leu Phe Arg Arg Val Pro Gly Ala Leu Arg Gly Leu Ala Asn 
145                 150                 155                 160 


Leu Thr His Ala His Leu Glu Arg Gly Arg Ile Glu Ala Val Ala Ser 
                165                 170                 175     


Ser Ser Leu Gln Gly Leu Arg Arg Leu Arg Ser Leu Ser Leu Gln Ala 
            180                 185                 190         


Asn Arg Val Arg Ala Val His Ala Gly Ala Phe Gly Asp Cys Gly Val 
        195                 200                 205             


Leu Glu His Leu Leu Leu Asn Asp Asn Leu Leu Ala Glu Leu Pro Ala 
    210                 215                 220                 


Asp Ala Phe Arg Gly Leu Arg Arg Leu Arg Thr Leu Asn Leu Gly Gly 
225                 230                 235                 240 


Asn Ala Leu Asp Arg Val Ala Arg Ala Trp Phe Ala Asp Leu Ala Glu 
                245                 250                 255     


Leu Glu Leu Leu Tyr Leu Asp Arg Asn Ser Ile Ala Phe Val Glu Glu 
            260                 265                 270         


Gly Ala Phe Gln Asn Leu Ser Gly Leu Leu Ala Leu His Leu Asn Gly 
        275                 280                 285             


Asn Arg Leu Thr Val Leu Ala Trp Val Ala Phe Gln Pro Gly Phe Phe 
    290                 295                 300                 


Leu Gly Arg Leu Phe Leu Phe Arg Asn Pro Trp Cys Cys Asp Cys Arg 
305                 310                 315                 320 


Leu Glu Trp Leu Arg Asp Trp Met Glu Gly Ser Gly Arg Val Thr Asp 
                325                 330                 335     


Val Pro Cys Ala Ser Pro Gly Ser Val Ala Gly Leu Asp Leu Ser Gln 
            340                 345                 350         


Val Thr Phe Gly Arg Ser Ser Asp Gly Leu Cys Val Asp Pro Glu Glu 
        355                 360                 365             


Leu Asn Leu Thr Thr Ser Ser Pro Gly Pro Ser Pro Glu Pro Ala Ala 
    370                 375                 380                 


Thr Thr Val Ser Arg Phe Ser Ser Leu Leu Ser Lys Leu Leu Ala Pro 
385                 390                 395                 400 


Arg Val Pro Val Glu Glu Ala Ala Asn Thr Thr Gly Gly Leu Ala Asn 
                405                 410                 415     


Ala Ser Leu Ser Asp Ser Leu Ser Ser Arg Gly Val Gly Gly Ala Gly 
            420                 425                 430         


Arg Gln Pro Trp Phe Leu Leu Ala Ser Cys Leu Leu Pro Ser Val Ala 
        435                 440                 445             


Gln His Val Val Phe Gly Leu Gln Met Asp 
    450                 455             


<210>  1029
<211>  278
<212>  PRT
<213>  Homo Sapiens

<400>  1029

Pro Pro Thr Gln Gln Asp Ser Arg Ile Ile Tyr Asp Tyr Gly Thr Asp 
1               5                   10                  15      


Asn Phe Glu Glu Ser Ile Phe Ser Gln Asp Tyr Glu Asp Lys Tyr Leu 
            20                  25                  30          


Asp Gly Lys Asn Ile Lys Glu Lys Glu Thr Val Ile Ile Pro Asn Glu 
        35                  40                  45              


Lys Ser Leu Gln Leu Gln Lys Asp Glu Ala Ile Thr Pro Leu Pro Pro 
    50                  55                  60                  


Lys Lys Glu Asn Asp Glu Met Pro Thr Cys Leu Leu Cys Val Cys Leu 
65                  70                  75                  80  


Ser Gly Ser Val Tyr Cys Glu Glu Val Asp Ile Asp Ala Val Pro Pro 
                85                  90                  95      


Leu Pro Lys Glu Ser Ala Tyr Leu Tyr Ala Arg Phe Asn Lys Ile Lys 
            100                 105                 110         


Lys Leu Thr Ala Lys Asp Phe Ala Asp Ile Pro Asn Leu Arg Arg Leu 
        115                 120                 125             


Asp Phe Thr Gly Asn Leu Ile Glu Asp Ile Glu Asp Gly Thr Phe Ser 
    130                 135                 140                 


Lys Leu Ser Leu Leu Glu Glu Leu Ser Leu Ala Glu Asn Gln Leu Leu 
145                 150                 155                 160 


Lys Leu Pro Val Leu Pro Pro Lys Leu Thr Leu Phe Asn Ala Lys Tyr 
                165                 170                 175     


Asn Lys Ile Lys Ser Arg Gly Ile Lys Ala Asn Ala Phe Lys Lys Leu 
            180                 185                 190         


Asn Asn Leu Thr Phe Leu Tyr Leu Asp His Asn Ala Leu Glu Ser Val 
        195                 200                 205             


Pro Leu Asn Leu Pro Glu Ser Leu Arg Val Ile His Leu Gln Phe Asn 
    210                 215                 220                 


Asn Ile Ala Ser Ile Thr Asp Asp Thr Phe Cys Lys Ala Asn Asp Thr 
225                 230                 235                 240 


Ser Tyr Ile Arg Asp Arg Ile Glu Glu Ile Arg Leu Glu Gly Asn Pro 
                245                 250                 255     


Ile Val Leu Gly Lys His Pro Asn Ser Phe Ile Cys Leu Lys Arg Leu 
            260                 265                 270         


Pro Ile Gly Ser Tyr Phe 
        275             


<210>  1030
<211>  523
<212>  PRT
<213>  Homo Sapiens

<400>  1030

Asp Pro Cys Ser Ala Tyr Ile Ser Leu Asn Glu Pro Trp Arg Asn Thr 
1               5                   10                  15      


Asp His Gln Leu Asp Glu Ser Gln Gly Pro Pro Leu Cys Asp Asn His 
            20                  25                  30          


Val Asn Gly Glu Trp Tyr His Phe Thr Gly Met Ala Gly Asp Ala Met 
        35                  40                  45              


Pro Thr Phe Cys Ile Pro Glu Asn His Cys Gly Thr His Ala Pro Val 
    50                  55                  60                  


Trp Leu Asn Gly Ser His Pro Leu Glu Gly Asp Gly Ile Val Gln Arg 
65                  70                  75                  80  


Gln Ala Cys Ala Ser Phe Asn Gly Asn Cys Cys Leu Trp Asn Thr Thr 
                85                  90                  95      


Val Glu Val Lys Ala Cys Pro Gly Gly Tyr Tyr Val Tyr Arg Leu Thr 
            100                 105                 110         


Lys Pro Ser Val Cys Phe His Val Tyr Cys Gly His Phe Tyr Asp Ile 
        115                 120                 125             


Cys Asp Glu Asp Cys His Gly Ser Cys Ser Asp Thr Ser Glu Cys Thr 
    130                 135                 140                 


Cys Ala Pro Gly Thr Val Leu Gly Pro Asp Arg Gln Thr Cys Phe Asp 
145                 150                 155                 160 


Glu Asn Glu Cys Glu Gln Asn Asn Gly Gly Cys Ser Glu Ile Cys Val 
                165                 170                 175     


Asn Leu Lys Asn Ser Tyr Arg Cys Glu Cys Gly Val Gly Arg Val Leu 
            180                 185                 190         


Arg Ser Asp Gly Lys Thr Cys Glu Asp Val Glu Gly Cys His Asn Asn 
        195                 200                 205             


Asn Gly Gly Cys Ser His Ser Cys Leu Gly Ser Glu Lys Gly Tyr Gln 
    210                 215                 220                 


Cys Glu Cys Pro Arg Gly Leu Val Leu Ser Glu Asp Asn His Thr Cys 
225                 230                 235                 240 


Gln Val Pro Val Leu Cys Lys Ser Asn Ala Ile Glu Val Asn Ile Pro 
                245                 250                 255     


Arg Glu Leu Val Gly Gly Leu Glu Leu Phe Leu Thr Asn Thr Ser Cys 
            260                 265                 270         


Arg Gly Val Ser Asn Gly Thr His Val Asn Ile Leu Phe Ser Leu Lys 
        275                 280                 285             


Thr Cys Gly Thr Val Val Asp Val Val Asn Asp Lys Ile Val Ala Ser 
    290                 295                 300                 


Asn Leu Val Thr Gly Leu Pro Lys Gln Thr Pro Gly Ser Ser Gly Asp 
305                 310                 315                 320 


Phe Ile Ile Arg Thr Ser Lys Leu Leu Ile Pro Val Thr Cys Glu Phe 
                325                 330                 335     


Pro Arg Leu Tyr Thr Ile Ser Glu Gly Tyr Val Pro Asn Leu Arg Asn 
            340                 345                 350         


Ser Pro Leu Glu Ile Met Ser Arg Asn His Gly Ile Phe Pro Phe Thr 
        355                 360                 365             


Leu Glu Ile Phe Lys Asp Asn Glu Phe Glu Glu Pro Tyr Arg Glu Ala 
    370                 375                 380                 


Leu Pro Thr Leu Lys Leu Arg Asp Ser Leu Tyr Phe Gly Ile Glu Pro 
385                 390                 395                 400 


Val Val His Val Ser Gly Leu Glu Ser Leu Val Glu Ser Cys Phe Ala 
                405                 410                 415     


Thr Pro Thr Ser Lys Ile Asp Glu Val Leu Lys Tyr Tyr Leu Ile Arg 
            420                 425                 430         


Asp Gly Cys Val Ser Asp Asp Ser Val Lys Gln Tyr Thr Ser Arg Asp 
        435                 440                 445             


His Leu Ala Lys His Phe Gln Val Pro Val Phe Lys Phe Val Gly Lys 
    450                 455                 460                 


Asp His Lys Glu Val Phe Leu His Cys Arg Val Leu Val Cys Gly Val 
465                 470                 475                 480 


Leu Asp Glu Arg Ser Arg Cys Ala Gln Gly Cys His Arg Arg Met Arg 
                485                 490                 495     


Arg Gly Ala Gly Gly Glu Asp Ser Ala Gly Leu Gln Gly Gln Thr Leu 
            500                 505                 510         


Thr Gly Gly Pro Ile Arg Ile Asp Trp Glu Asp 
        515                 520             


<210>  1031
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  1031

Met Gln Leu Ser Gln Val Ser Asp Leu Leu Thr Gln Glu Gln Ala Asn 
1               5                   10                  15      


Leu Thr His Gln Lys Lys Lys Leu Glu Gly Gln Ile Ser Ala Arg Gln 
            20                  25                  30          


Gln Ala Glu Glu Ala Ser Gln Glu Ser Glu Asn Glu Leu Lys Glu Met 
        35                  40                  45              


Ile Glu Thr Leu Ala Arg Lys Leu Asn Glu Lys Ser Lys Glu Gln Met 
    50                  55                  60                  


Glu Leu His His Gln Asn Leu Asn Leu Gln Glu Thr Leu Lys Arg Val 
65                  70                  75                  80  


Ala Asn Cys Ser Ala Pro Cys Pro Gln Asp Trp Ile Trp His Gly Glu 
                85                  90                  95      


Asn Cys Tyr Leu Phe Ser Ser Gly Ser Phe Asn Trp Glu Lys Ser Gln 
            100                 105                 110         


Glu Lys Cys Leu Ser Leu Asp Ala Lys Leu Leu Lys Ile Asn Ser Thr 
        115                 120                 125             


Ala Asp Leu Asp Phe Ile Gln Gln Ala Ile Ser Tyr Ser Ser Phe Pro 
    130                 135                 140                 


Phe Trp Met Gly Leu Ser Arg Arg Asn Pro Ser Tyr Pro Trp Leu Trp 
145                 150                 155                 160 


Glu Asp Gly Ser Pro Leu Met Pro His Leu Phe Arg Val Arg Gly Ala 
                165                 170                 175     


Val Ser Gln Thr Tyr Pro Ser Gly Thr Cys Ala Tyr Ile Gln Arg Gly 
            180                 185                 190         


Ala Val Tyr Ala Glu Asn Cys Ile Leu Ala Ala Phe Ser Ile Cys Gln 
        195                 200                 205             


Lys Lys Ala Asn Leu Arg Ala Gln 
    210                 215     


<210>  1032
<211>  401
<212>  PRT
<213>  Homo Sapiens

<400>  1032

Gln Tyr Glu Thr Tyr Gln Trp Asp Glu Asp Tyr Asp Gln Glu Pro Asp 
1               5                   10                  15      


Asp Asp Tyr Gln Thr Gly Phe Pro Phe Arg Gln Asn Val Asp Tyr Gly 
            20                  25                  30          


Val Pro Phe His Gln Tyr Thr Leu Gly Cys Val Ser Glu Cys Phe Cys 
        35                  40                  45              


Pro Thr Asn Phe Pro Ser Ser Met Tyr Cys Asp Asn Arg Lys Leu Lys 
    50                  55                  60                  


Thr Ile Pro Asn Ile Pro Met His Ile Gln Gln Leu Tyr Leu Gln Phe 
65                  70                  75                  80  


Asn Glu Ile Glu Ala Val Thr Ala Asn Ser Phe Ile Asn Ala Thr His 
                85                  90                  95      


Leu Lys Glu Ile Asn Leu Ser His Asn Lys Ile Lys Ser Gln Lys Ile 
            100                 105                 110         


Asp Tyr Gly Val Phe Ala Lys Leu Pro Asn Leu Leu Gln Leu His Leu 
        115                 120                 125             


Glu His Asn Asn Leu Glu Glu Phe Pro Phe Pro Leu Pro Lys Ser Leu 
    130                 135                 140                 


Glu Arg Leu Leu Leu Gly Tyr Asn Glu Ile Ser Lys Leu Gln Thr Asn 
145                 150                 155                 160 


Ala Met Asp Gly Leu Val Asn Leu Thr Met Leu Asp Leu Cys Tyr Asn 
                165                 170                 175     


Tyr Leu His Asp Ser Leu Leu Lys Asp Lys Ile Phe Ala Lys Met Glu 
            180                 185                 190         


Lys Leu Met Gln Leu Asn Leu Cys Ser Asn Arg Leu Glu Ser Met Pro 
        195                 200                 205             


Pro Gly Leu Pro Ser Ser Leu Met Tyr Leu Ser Leu Glu Asn Asn Ser 
    210                 215                 220                 


Ile Ser Ser Ile Pro Glu Lys Tyr Phe Asp Lys Leu Pro Lys Leu His 
225                 230                 235                 240 


Thr Leu Arg Met Ser His Asn Lys Leu Gln Asp Ile Pro Tyr Asn Ile 
                245                 250                 255     


Phe Asn Leu Pro Asn Ile Val Glu Leu Ser Val Gly His Asn Lys Leu 
            260                 265                 270         


Lys Gln Ala Phe Tyr Ile Pro Arg Asn Leu Glu His Leu Tyr Leu Gln 
        275                 280                 285             


Asn Asn Glu Ile Glu Lys Met Asn Leu Thr Val Met Cys Pro Ser Ile 
    290                 295                 300                 


Asp Pro Leu His Tyr His His Leu Thr Tyr Ile Arg Val Asp Gln Asn 
305                 310                 315                 320 


Lys Leu Lys Glu Pro Ile Ser Ser Tyr Ile Phe Phe Cys Phe Pro His 
                325                 330                 335     


Ile His Thr Ile Tyr Tyr Gly Glu Gln Arg Ser Thr Asn Gly Gln Thr 
            340                 345                 350         


Ile Gln Leu Lys Thr Gln Val Phe Arg Arg Phe Pro Asp Asp Asp Asp 
        355                 360                 365             


Glu Ser Glu Asp His Asp Asp Pro Asp Asn Ala His Glu Ser Pro Glu 
    370                 375                 380                 


Gln Glu Gly Ala Glu Gly His Phe Asp Leu His Tyr Tyr Glu Asn Gln 
385                 390                 395                 400 


Glu 
    


<210>  1033
<211>  393
<212>  PRT
<213>  Homo Sapiens

<400>  1033

Ile Cys Pro Leu Gln Cys Ile Cys Thr Glu Arg His Arg His Val Asp 
1               5                   10                  15      


Cys Ser Gly Arg Asn Leu Ser Thr Leu Pro Ser Gly Leu Gln Glu Asn 
            20                  25                  30          


Ile Ile His Leu Asn Leu Ser Tyr Asn His Phe Thr Asp Leu His Asn 
        35                  40                  45              


Gln Leu Thr Gln Tyr Thr Asn Leu Arg Thr Leu Asp Ile Ser Asn Asn 
    50                  55                  60                  


Arg Leu Glu Ser Leu Pro Ala His Leu Pro Arg Ser Leu Trp Asn Met 
65                  70                  75                  80  


Ser Ala Ala Asn Asn Asn Ile Lys Leu Leu Asp Lys Ser Asp Thr Ala 
                85                  90                  95      


Tyr Gln Trp Asn Leu Lys Tyr Leu Asp Val Ser Lys Asn Met Leu Glu 
            100                 105                 110         


Lys Val Val Leu Ile Lys Asn Thr Leu Arg Ser Leu Glu Val Leu Asn 
        115                 120                 125             


Leu Ser Ser Asn Lys Leu Trp Thr Val Pro Thr Asn Met Pro Ser Lys 
    130                 135                 140                 


Leu His Ile Val Asp Leu Ser Asn Asn Ser Leu Thr Gln Ile Leu Pro 
145                 150                 155                 160 


Gly Thr Leu Ile Asn Leu Thr Asn Leu Thr His Leu Tyr Leu His Asn 
                165                 170                 175     


Asn Lys Phe Thr Phe Ile Pro Asp Gln Ser Phe Asp Gln Leu Phe Gln 
            180                 185                 190         


Leu Gln Glu Ile Thr Leu Tyr Asn Asn Arg Trp Ser Cys Asp His Lys 
        195                 200                 205             


Gln Asn Ile Thr Tyr Leu Leu Lys Trp Met Met Glu Thr Lys Ala His 
    210                 215                 220                 


Val Ile Gly Thr Pro Cys Ser Thr Gln Ile Ser Ser Leu Lys Glu His 
225                 230                 235                 240 


Asn Met Tyr Pro Thr Pro Ser Gly Phe Thr Ser Ser Leu Phe Thr Val 
                245                 250                 255     


Ser Gly Met Gln Thr Val Asp Thr Ile Asn Ser Leu Ser Val Val Thr 
            260                 265                 270         


Gln Pro Lys Val Thr Lys Ile Pro Lys Gln Tyr Arg Thr Lys Glu Thr 
        275                 280                 285             


Thr Phe Gly Ala Thr Leu Ser Lys Asp Thr Thr Phe Thr Ser Thr Asp 
    290                 295                 300                 


Lys Ala Phe Val Pro Tyr Pro Glu Asp Thr Ser Thr Glu Thr Ile Asn 
305                 310                 315                 320 


Ser His Glu Ala Ala Ala Ala Thr Leu Thr Ile His Leu Gln Asp Gly 
                325                 330                 335     


Met Val Thr Asn Thr Ser Leu Thr Ser Ser Thr Lys Ser Ser Pro Thr 
            340                 345                 350         


Pro Met Thr Leu Ser Ile Thr Ser Gly Met Pro Asn Asn Phe Ser Glu 
        355                 360                 365             


Met Pro Gln Gln Ser Thr Thr Leu Asn Leu Trp Arg Glu Glu Thr Thr 
    370                 375                 380                 


Thr Asn Val Lys Thr Pro Leu Pro Ser 
385                 390             


<210>  1034
<211>  295
<212>  PRT
<213>  Homo Sapiens

<400>  1034

Gly Val Pro Val Arg Ser Gly Asp Ala Thr Phe Pro Lys Ala Met Asp 
1               5                   10                  15      


Asn Val Thr Val Arg Gln Gly Glu Ser Ala Thr Leu Arg Cys Thr Ile 
            20                  25                  30          


Asp Asp Arg Val Thr Arg Val Ala Trp Leu Asn Arg Ser Thr Ile Leu 
        35                  40                  45              


Tyr Ala Gly Asn Asp Lys Trp Ser Ile Asp Pro Arg Val Ile Ile Leu 
    50                  55                  60                  


Val Asn Thr Pro Thr Gln Tyr Ser Ile Met Ile Gln Asn Val Asp Val 
65                  70                  75                  80  


Tyr Asp Glu Gly Pro Tyr Thr Cys Ser Val Gln Thr Asp Asn His Pro 
                85                  90                  95      


Lys Thr Ser Arg Val His Leu Ile Val Gln Val Pro Pro Gln Ile Met 
            100                 105                 110         


Asn Ile Ser Ser Asp Ile Thr Val Asn Glu Gly Ser Ser Val Thr Leu 
        115                 120                 125             


Leu Cys Leu Ala Ile Gly Arg Pro Glu Pro Thr Val Thr Trp Arg His 
    130                 135                 140                 


Leu Ser Val Lys Glu Gly Gln Gly Phe Val Ser Glu Asp Glu Tyr Leu 
145                 150                 155                 160 


Glu Ile Ser Asp Ile Lys Arg Asp Gln Ser Gly Glu Tyr Glu Cys Ser 
                165                 170                 175     


Ala Leu Asn Asp Val Ala Ala Pro Asp Val Arg Lys Val Lys Ile Thr 
            180                 185                 190         


Val Asn Tyr Pro Pro Tyr Ile Ser Lys Ala Lys Asn Thr Gly Val Ser 
        195                 200                 205             


Val Gly Gln Lys Gly Ile Leu Ser Cys Glu Ala Ser Ala Val Pro Met 
    210                 215                 220                 


Ala Glu Phe Gln Trp Phe Lys Glu Glu Thr Arg Leu Ala Thr Gly Leu 
225                 230                 235                 240 


Asp Gly Met Arg Ile Glu Asn Lys Gly Arg Met Ser Thr Leu Thr Phe 
                245                 250                 255     


Phe Asn Val Ser Glu Lys Asp Tyr Gly Asn Tyr Thr Cys Val Ala Thr 
            260                 265                 270         


Asn Lys Leu Gly Asn Thr Asn Ala Ser Ile Thr Leu Tyr Gly Pro Gly 
        275                 280                 285             


Ala Val Ile Asp Gly Val Asn 
    290                 295 


<210>  1035
<211>  313
<212>  PRT
<213>  Homo Sapiens

<400>  1035

Ala Ser Leu Pro Arg Lys Glu Arg Lys Arg Arg Glu Glu Gln Met Pro 
1               5                   10                  15      


Arg Glu Gly Asp Ser Phe Glu Val Leu Pro Leu Arg Asn Asp Val Leu 
            20                  25                  30          


Asn Pro Asp Asn Tyr Gly Glu Val Ile Asp Leu Ser Asn Tyr Glu Glu 
        35                  40                  45              


Leu Thr Asp Tyr Gly Asp Gln Leu Pro Glu Val Lys Val Thr Ser Leu 
    50                  55                  60                  


Ala Pro Ala Thr Ser Ile Ser Pro Ala Lys Ser Thr Thr Ala Pro Gly 
65                  70                  75                  80  


Thr Pro Ser Ser Asn Pro Thr Met Thr Arg Pro Thr Thr Ala Gly Leu 
                85                  90                  95      


Leu Leu Ser Ser Gln Pro Asn His Gly Leu Pro Thr Cys Leu Val Cys 
            100                 105                 110         


Val Cys Leu Gly Ser Ser Val Tyr Cys Asp Asp Ile Asp Leu Glu Asp 
        115                 120                 125             


Ile Pro Pro Leu Pro Arg Arg Thr Ala Tyr Leu Tyr Ala Arg Phe Asn 
    130                 135                 140                 


Arg Ile Ser Arg Ile Arg Ala Glu Asp Phe Lys Gly Leu Thr Lys Leu 
145                 150                 155                 160 


Lys Arg Ile Asp Leu Ser Asn Asn Leu Ile Ser Ser Ile Asp Asn Asp 
                165                 170                 175     


Ala Phe Arg Leu Leu His Ala Leu Gln Asp Leu Ile Leu Pro Glu Asn 
            180                 185                 190         


Gln Leu Glu Ala Leu Pro Val Leu Pro Ser Gly Ile Glu Phe Leu Asp 
        195                 200                 205             


Val Arg Leu Asn Arg Leu Gln Ser Ser Gly Ile Gln Pro Ala Ala Phe 
    210                 215                 220                 


Arg Ala Met Glu Lys Leu Gln Phe Leu Tyr Leu Ser Asp Asn Leu Leu 
225                 230                 235                 240 


Asp Ser Ile Pro Gly Pro Leu Pro Leu Ser Leu Arg Ser Val His Leu 
                245                 250                 255     


Gln Asn Asn Leu Ile Glu Thr Met Gln Arg Asp Val Phe Cys Asp Pro 
            260                 265                 270         


Glu Glu His Lys His Thr Arg Arg Gln Leu Glu Asp Ile Arg Leu Asp 
        275                 280                 285             


Gly Asn Pro Ile Asn Leu Ser Leu Phe Pro Ser Ala Tyr Phe Cys Leu 
    290                 295                 300                 


Pro Arg Leu Pro Ile Gly Arg Phe Thr 
305                 310             


<210>  1036
<211>  264
<212>  PRT
<213>  Homo Sapiens

<400>  1036

Asp Ile Thr Pro Ser Val Pro Pro Ala Ser Tyr His Pro Lys Pro Trp 
1               5                   10                  15      


Leu Gly Ala Gln Pro Ala Thr Val Val Thr Pro Gly Val Asn Val Thr 
            20                  25                  30          


Leu Arg Cys Arg Ala Pro Gln Pro Ala Trp Arg Phe Gly Leu Phe Lys 
        35                  40                  45              


Pro Gly Glu Ile Ala Pro Leu Leu Phe Arg Asp Val Ser Ser Glu Leu 
    50                  55                  60                  


Ala Glu Phe Phe Leu Glu Glu Val Thr Pro Ala Gln Gly Gly Ser Tyr 
65                  70                  75                  80  


Arg Cys Cys Tyr Arg Arg Pro Asp Trp Gly Pro Gly Val Trp Ser Gln 
                85                  90                  95      


Pro Ser Asp Val Leu Glu Leu Leu Val Thr Glu Glu Leu Pro Arg Pro 
            100                 105                 110         


Ser Leu Val Ala Leu Pro Gly Pro Val Val Gly Pro Gly Ala Asn Val 
        115                 120                 125             


Ser Leu Arg Cys Ala Gly Arg Leu Arg Asn Met Ser Phe Val Leu Tyr 
    130                 135                 140                 


Arg Glu Gly Val Ala Ala Pro Leu Gln Tyr Arg His Ser Ala Gln Pro 
145                 150                 155                 160 


Trp Ala Asp Phe Thr Leu Leu Gly Ala Arg Ala Pro Gly Thr Tyr Ser 
                165                 170                 175     


Cys Tyr Tyr His Thr Pro Ser Ala Pro Tyr Val Leu Ser Gln Arg Ser 
            180                 185                 190         


Glu Val Leu Val Ile Ser Trp Glu Gly Glu Gly Pro Glu Ala Arg Pro 
        195                 200                 205             


Ala Ser Ser Ala Pro Gly Met Gln Ala Pro Gly Pro Pro Pro Ser Asp 
    210                 215                 220                 


Pro Gly Ala Gln Ala Pro Ser Leu Ser Ser Phe Arg Pro Arg Gly Leu 
225                 230                 235                 240 


Val Leu Gln Pro Leu Leu Pro Gln Thr Gln Asp Ser Trp Asp Pro Ala 
                245                 250                 255     


Pro Pro Pro Ser Asp Pro Gly Val 
            260                 


<210>  1037
<211>  713
<212>  PRT
<213>  Homo Sapiens

<400>  1037

Glu Arg Leu Pro Leu Thr Pro Val Ser Leu Lys Val Ser Thr Asn Ser 
1               5                   10                  15      


Thr Arg Gln Ser Leu His Leu Gln Trp Thr Val His Asn Leu Pro Tyr 
            20                  25                  30          


His Gln Glu Leu Lys Met Val Phe Gln Ile Gln Ile Ser Arg Ile Glu 
        35                  40                  45              


Thr Ser Asn Val Ile Trp Val Gly Asn Tyr Ser Thr Thr Val Lys Trp 
    50                  55                  60                  


Asn Gln Val Leu His Trp Ser Trp Glu Ser Glu Leu Pro Leu Glu Cys 
65                  70                  75                  80  


Ala Thr His Phe Val Arg Ile Lys Ser Leu Val Asp Asp Ala Lys Phe 
                85                  90                  95      


Pro Glu Pro Asn Phe Trp Ser Asn Trp Ser Ser Trp Glu Glu Val Ser 
            100                 105                 110         


Val Gln Asp Ser Thr Gly Gln Asp Ile Leu Phe Val Phe Pro Lys Asp 
        115                 120                 125             


Lys Leu Val Glu Glu Gly Thr Asn Val Thr Ile Cys Tyr Val Ser Arg 
    130                 135                 140                 


Asn Ile Gln Asn Asn Val Ser Cys Tyr Leu Glu Gly Lys Gln Ile His 
145                 150                 155                 160 


Gly Glu Gln Leu Asp Pro His Val Thr Ala Phe Asn Leu Asn Ser Val 
                165                 170                 175     


Pro Phe Ile Arg Asn Lys Gly Thr Asn Ile Tyr Cys Glu Ala Ser Gln 
            180                 185                 190         


Gly Asn Val Ser Glu Gly Met Lys Gly Ile Val Leu Phe Val Ser Lys 
        195                 200                 205             


Val Leu Glu Glu Pro Lys Asp Phe Ser Cys Glu Thr Glu Asp Phe Lys 
    210                 215                 220                 


Thr Leu His Cys Thr Trp Asp Pro Gly Thr Asp Thr Ala Leu Gly Trp 
225                 230                 235                 240 


Ser Lys Gln Pro Ser Gln Ser Tyr Thr Leu Phe Glu Ser Phe Ser Gly 
                245                 250                 255     


Glu Lys Lys Leu Cys Thr His Lys Asn Trp Cys Asn Trp Gln Ile Thr 
            260                 265                 270         


Gln Asp Ser Gln Glu Thr Tyr Asn Phe Thr Leu Ile Ala Glu Asn Tyr 
        275                 280                 285             


Leu Arg Lys Arg Ser Val Asn Ile Leu Phe Asn Leu Thr His Arg Val 
    290                 295                 300                 


Tyr Leu Met Asn Pro Phe Ser Val Asn Phe Glu Asn Val Asn Ala Thr 
305                 310                 315                 320 


Asn Ala Ile Met Thr Trp Lys Val His Ser Ile Arg Asn Asn Phe Thr 
                325                 330                 335     


Tyr Leu Cys Gln Ile Glu Leu His Gly Glu Gly Lys Met Met Gln Tyr 
            340                 345                 350         


Asn Val Ser Ile Lys Val Asn Gly Glu Tyr Phe Leu Ser Glu Leu Glu 
        355                 360                 365             


Pro Ala Thr Glu Tyr Met Ala Arg Val Arg Cys Ala Asp Ala Ser His 
    370                 375                 380                 


Phe Trp Lys Trp Ser Glu Trp Ser Gly Gln Asn Phe Thr Thr Leu Glu 
385                 390                 395                 400 


Ala Ala Pro Ser Glu Ala Pro Asp Val Trp Arg Ile Val Ser Leu Glu 
                405                 410                 415     


Pro Gly Asn His Thr Val Thr Leu Phe Trp Lys Pro Leu Ser Lys Leu 
            420                 425                 430         


His Ala Asn Gly Lys Ile Leu Phe Tyr Asn Val Val Val Glu Asn Leu 
        435                 440                 445             


Asp Lys Pro Ser Ser Ser Glu Leu His Ser Ile Pro Ala Pro Ala Asn 
    450                 455                 460                 


Ser Thr Lys Leu Ile Leu Asp Arg Cys Ser Tyr Gln Ile Cys Val Ile 
465                 470                 475                 480 


Ala Asn Asn Ser Val Gly Ala Ser Pro Ala Ser Val Ile Val Ile Ser 
                485                 490                 495     


Ala Asp Pro Glu Asn Lys Glu Val Glu Glu Glu Arg Ile Ala Gly Thr 
            500                 505                 510         


Glu Gly Gly Phe Ser Leu Ser Trp Lys Pro Gln Pro Gly Asp Val Ile 
        515                 520                 525             


Gly Tyr Val Val Asp Trp Cys Asp His Thr Gln Asp Val Leu Gly Asp 
    530                 535                 540                 


Phe Gln Trp Lys Asn Val Gly Pro Asn Thr Thr Ser Thr Val Ile Ser 
545                 550                 555                 560 


Thr Asp Ala Phe Arg Pro Gly Val Arg Tyr Asp Phe Arg Ile Tyr Gly 
                565                 570                 575     


Leu Ser Thr Lys Arg Ile Ala Cys Leu Leu Glu Lys Lys Thr Gly Tyr 
            580                 585                 590         


Ser Gln Glu Leu Ala Pro Ser Asp Asn Pro His Val Leu Val Asp Thr 
        595                 600                 605             


Leu Thr Ser His Ser Phe Thr Leu Ser Trp Lys Asp Tyr Ser Thr Glu 
    610                 615                 620                 


Ser Gln Pro Gly Phe Ile Gln Gly Tyr His Val Tyr Leu Lys Ser Lys 
625                 630                 635                 640 


Ala Arg Gln Cys His Pro Arg Phe Glu Lys Ala Val Leu Ser Asp Gly 
                645                 650                 655     


Ser Glu Cys Cys Lys Tyr Lys Ile Asp Asn Pro Glu Glu Lys Ala Leu 
            660                 665                 670         


Ile Val Asp Asn Leu Lys Pro Glu Ser Phe Tyr Glu Phe Phe Ile Thr 
        675                 680                 685             


Pro Phe Thr Ser Ala Gly Glu Gly Pro Ser Ala Thr Phe Thr Lys Val 
    690                 695                 700                 


Thr Thr Pro Asp Glu His Ser Ser Met 
705                 710             


<210>  1038
<211>  716
<212>  PRT
<213>  Homo Sapiens

<400>  1038

Leu Pro Arg Glu Tyr Thr Val Ile Asn Glu Ala Cys Pro Gly Ala Glu 
1               5                   10                  15      


Trp Asn Ile Met Cys Arg Glu Cys Cys Glu Tyr Asp Gln Ile Glu Cys 
            20                  25                  30          


Val Cys Pro Gly Lys Arg Glu Val Val Gly Tyr Thr Ile Pro Cys Cys 
        35                  40                  45              


Arg Asn Glu Glu Asn Glu Cys Asp Ser Cys Leu Ile His Pro Gly Cys 
    50                  55                  60                  


Thr Ile Phe Glu Asn Cys Lys Ser Cys Arg Asn Gly Ser Trp Gly Gly 
65                  70                  75                  80  


Thr Leu Asp Asp Phe Tyr Val Lys Gly Phe Tyr Cys Ala Glu Cys Arg 
                85                  90                  95      


Ala Gly Trp Tyr Gly Gly Asp Cys Met Arg Cys Gly Gln Val Leu Arg 
            100                 105                 110         


Ala Pro Lys Gly Gln Ile Leu Leu Glu Ser Tyr Pro Leu Asn Ala His 
        115                 120                 125             


Cys Glu Trp Thr Ile His Ala Lys Pro Gly Phe Val Ile Gln Leu Arg 
    130                 135                 140                 


Phe Val Met Leu Ser Leu Glu Phe Asp Tyr Met Cys Gln Tyr Asp Tyr 
145                 150                 155                 160 


Val Glu Val Arg Asp Gly Asp Asn Arg Asp Gly Gln Ile Ile Lys Arg 
                165                 170                 175     


Val Cys Gly Asn Glu Arg Pro Ala Pro Ile Gln Ser Ile Gly Ser Ser 
            180                 185                 190         


Leu His Val Leu Phe His Ser Asp Gly Ser Lys Asn Phe Asp Gly Phe 
        195                 200                 205             


His Ala Ile Tyr Glu Glu Ile Thr Ala Cys Ser Ser Ser Pro Cys Phe 
    210                 215                 220                 


His Asp Gly Thr Cys Val Leu Asp Lys Ala Gly Ser Tyr Lys Cys Ala 
225                 230                 235                 240 


Cys Leu Ala Gly Tyr Thr Gly Gln Arg Cys Glu Asn Leu Leu Glu Ala 
                245                 250                 255     


Gly Lys Ser Lys Ile Lys Ala Ser Glu Asp Ser Leu Ser Val Leu Glu 
            260                 265                 270         


Glu Arg Asn Cys Ser Asp Pro Gly Gly Pro Val Asn Gly Tyr Gln Lys 
        275                 280                 285             


Ile Thr Gly Gly Pro Gly Leu Ile Asn Gly Arg His Ala Lys Ile Gly 
    290                 295                 300                 


Thr Val Val Ser Phe Phe Cys Asn Asn Ser Tyr Val Leu Ser Gly Asn 
305                 310                 315                 320 


Glu Lys Arg Thr Cys Gln Gln Asn Gly Glu Trp Ser Gly Lys Gln Pro 
                325                 330                 335     


Ile Cys Ile Lys Ala Cys Arg Glu Pro Lys Ile Ser Asp Leu Val Arg 
            340                 345                 350         


Arg Arg Val Leu Pro Met Gln Val Gln Ser Arg Glu Thr Pro Leu His 
        355                 360                 365             


Gln Leu Tyr Ser Ala Ala Phe Ser Lys Gln Lys Leu Gln Ser Ala Pro 
    370                 375                 380                 


Thr Lys Lys Pro Ala Leu Pro Phe Gly Asp Leu Pro Met Gly Tyr Gln 
385                 390                 395                 400 


His Leu His Thr Gln Leu Gln Tyr Glu Cys Ile Ser Pro Phe Tyr Arg 
                405                 410                 415     


Arg Leu Gly Ser Ser Arg Arg Thr Cys Leu Arg Thr Gly Lys Trp Ser 
            420                 425                 430         


Gly Arg Ala Pro Ser Cys Ile Pro Ile Cys Gly Lys Ile Glu Asn Ile 
        435                 440                 445             


Thr Ala Pro Lys Thr Gln Gly Leu Arg Trp Pro Trp Gln Ala Ala Ile 
    450                 455                 460                 


Tyr Arg Arg Thr Ser Gly Val His Asp Gly Ser Leu His Lys Gly Ala 
465                 470                 475                 480 


Trp Phe Leu Val Cys Ser Gly Ala Leu Val Asn Glu Arg Thr Val Val 
                485                 490                 495     


Val Ala Ala His Cys Val Thr Asp Leu Gly Lys Val Thr Met Ile Lys 
            500                 505                 510         


Thr Ala Asp Leu Lys Val Val Leu Gly Lys Phe Tyr Arg Asp Asp Asp 
        515                 520                 525             


Arg Asp Glu Lys Thr Ile Gln Ser Leu Gln Ile Ser Ala Ile Ile Leu 
    530                 535                 540                 


His Pro Asn Tyr Asp Pro Ile Leu Leu Asp Ala Asp Ile Ala Ile Leu 
545                 550                 555                 560 


Lys Leu Leu Asp Lys Ala Arg Ile Ser Thr Arg Val Gln Pro Ile Cys 
                565                 570                 575     


Leu Ala Ala Ser Arg Asp Leu Ser Thr Ser Phe Gln Glu Ser His Ile 
            580                 585                 590         


Thr Val Ala Gly Trp Asn Val Leu Ala Asp Val Arg Ser Pro Gly Phe 
        595                 600                 605             


Lys Asn Asp Thr Leu Arg Ser Gly Val Val Ser Val Val Asp Ser Leu 
    610                 615                 620                 


Leu Cys Glu Glu Gln His Glu Asp His Gly Ile Pro Val Ser Val Thr 
625                 630                 635                 640 


Asp Asn Met Phe Cys Ala Ser Trp Glu Pro Thr Ala Pro Ser Asp Ile 
                645                 650                 655     


Cys Thr Ala Glu Thr Gly Gly Ile Ala Ala Val Ser Phe Pro Gly Arg 
            660                 665                 670         


Ala Ser Pro Glu Pro Arg Trp His Leu Met Gly Leu Val Ser Trp Ser 
        675                 680                 685             


Tyr Asp Lys Thr Cys Ser His Arg Leu Ser Thr Ala Phe Thr Lys Val 
    690                 695                 700                 


Leu Pro Phe Lys Asp Trp Ile Glu Arg Asn Met Lys 
705                 710                 715     


<210>  1039
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  1039

Ile Arg Cys Pro Lys Gly Ser Lys Ala Tyr Gly Ser His Cys Tyr Ala 
1               5                   10                  15      


Leu Phe Leu Ser Pro Lys Ser Trp Thr Asp Ala Asp Leu Ala Cys Gln 
            20                  25                  30          


Lys Arg Pro Ser Gly Asn Leu Val Ser Val Leu Ser Gly Ala Glu Gly 
        35                  40                  45              


Ser Phe Val Ser Ser Leu Val Lys Ser Ile Gly Asn Ser Tyr Ser Tyr 
    50                  55                  60                  


Val Trp Ile Gly Leu His Asp Pro Thr Gln Gly Thr Glu Pro Asn Gly 
65                  70                  75                  80  


Glu Gly Trp Glu Trp Ser Ser Ser Asp Val Met Asn Tyr Phe Ala Trp 
                85                  90                  95      


Glu Arg Asn Pro Ser Thr Ile Ser Ser Pro Gly His Cys Ala Ser Leu 
            100                 105                 110         


Ser Arg Ser Thr Ala Phe Leu Arg Trp Lys Asp Tyr Asn Cys Asn Val 
        115                 120                 125             


Arg Leu Pro Tyr Val Cys Lys Phe Thr Asp 
    130                 135             


<210>  1040
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  1040

Ala Pro Lys Val Arg Arg Gln Ser Asp Thr Trp Gly Pro Trp Ser Gln 
1               5                   10                  15      


Trp Ser Pro Cys Ser Arg Thr Cys Gly Gly Gly Val Ser Phe Arg Glu 
            20                  25                  30          


Arg Pro Cys Tyr Ser Gln Arg Arg Asp Gly Gly Ser Ser Cys Val Gly 
        35                  40                  45              


Pro Ala Arg Ser His Arg Ser Cys Arg Thr Glu Ser Cys Pro Asp Gly 
    50                  55                  60                  


Ala Arg Asp Phe Arg Ala Glu Gln Cys Ala Glu Phe Asp Gly Ala Glu 
65                  70                  75                  80  


Phe Gln Gly Arg Arg Tyr Arg Trp Leu Pro Tyr Tyr Ser Ala Pro Asn 
                85                  90                  95      


Lys Cys Glu Leu Asn Cys Ile Pro Lys Val Leu Gly Leu Gln Ala 
            100                 105                 110     


<210>  1041
<211>  1547
<212>  PRT
<213>  Homo Sapiens

<400>  1041

Arg Glu Ala Arg Gly Ala Thr Glu Glu Pro Ser Pro Pro Ser Arg Ala 
1               5                   10                  15      


Leu Tyr Phe Ser Gly Arg Gly Glu Gln Leu Arg Leu Arg Ala Asp Leu 
            20                  25                  30          


Glu Leu Pro Arg Asp Ala Phe Thr Leu Gln Val Trp Leu Arg Ala Glu 
        35                  40                  45              


Gly Gly Gln Arg Ser Pro Ala Val Ile Thr Gly Leu Tyr Asp Lys Cys 
    50                  55                  60                  


Ser Tyr Ile Ser Arg Asp Arg Gly Trp Val Val Gly Ile His Thr Ile 
65                  70                  75                  80  


Ser Asp Gln Asp Asn Lys Asp Pro Arg Tyr Phe Phe Ser Leu Lys Thr 
                85                  90                  95      


Asp Arg Ala Arg Gln Val Thr Thr Ile Asn Ala His Arg Ser Tyr Leu 
            100                 105                 110         


Pro Gly Gln Trp Val Tyr Leu Ala Ala Thr Tyr Asp Gly Gln Phe Met 
        115                 120                 125             


Lys Leu Tyr Val Asn Gly Ala Gln Val Ala Thr Ser Gly Glu Gln Val 
    130                 135                 140                 


Gly Gly Ile Phe Ser Pro Leu Thr Gln Lys Cys Lys Val Leu Met Leu 
145                 150                 155                 160 


Gly Gly Ser Ala Leu Asn His Asn Tyr Arg Gly Tyr Ile Glu His Phe 
                165                 170                 175     


Ser Leu Trp Lys Val Ala Arg Thr Gln Arg Glu Ile Leu Ser Asp Met 
            180                 185                 190         


Glu Thr His Gly Ala His Thr Ala Leu Pro Gln Leu Leu Leu Gln Glu 
        195                 200                 205             


Asn Trp Asp Asn Val Lys His Ala Trp Ser Pro Met Lys Asp Gly Ser 
    210                 215                 220                 


Ser Pro Lys Val Glu Phe Ser Asn Ala His Gly Phe Leu Leu Asp Thr 
225                 230                 235                 240 


Ser Leu Glu Pro Pro Leu Cys Gly Gln Thr Leu Cys Asp Asn Thr Glu 
                245                 250                 255     


Val Ile Ala Ser Tyr Asn Gln Leu Ser Ser Phe Arg Gln Pro Lys Val 
            260                 265                 270         


Val Arg Tyr Arg Val Val Asn Leu Tyr Glu Asp Asp His Lys Asn Pro 
        275                 280                 285             


Thr Val Thr Arg Glu Gln Val Asp Phe Gln His His Gln Leu Ala Glu 
    290                 295                 300                 


Ala Phe Lys Gln Tyr Asn Ile Ser Trp Glu Leu Asp Val Leu Glu Val 
305                 310                 315                 320 


Ser Asn Ser Ser Leu Arg Arg Arg Leu Ile Leu Ala Asn Cys Asp Ile 
                325                 330                 335     


Ser Lys Ile Gly Asp Glu Asn Cys Asp Pro Glu Cys Asn His Thr Leu 
            340                 345                 350         


Thr Gly His Asp Gly Gly Asp Cys Arg His Leu Arg His Pro Ala Phe 
        355                 360                 365             


Val Lys Lys Gln His Asn Gly Val Cys Asp Met Asp Cys Asn Tyr Glu 
    370                 375                 380                 


Arg Phe Asn Phe Asp Gly Gly Glu Cys Cys Asp Pro Glu Ile Thr Asn 
385                 390                 395                 400 


Val Thr Gln Thr Cys Phe Asp Pro Asp Ser Pro His Arg Ala Tyr Leu 
                405                 410                 415     


Asp Val Asn Glu Leu Lys Asn Ile Leu Lys Leu Asp Gly Ser Thr His 
            420                 425                 430         


Leu Asn Ile Phe Phe Ala Lys Ser Ser Glu Glu Glu Leu Ala Gly Val 
        435                 440                 445             


Ala Thr Trp Pro Trp Asp Lys Glu Ala Leu Met His Leu Gly Gly Ile 
    450                 455                 460                 


Val Leu Asn Pro Ser Phe Tyr Gly Met Pro Gly His Thr His Thr Met 
465                 470                 475                 480 


Ile His Glu Ile Gly His Ser Leu Gly Leu Tyr His Val Phe Arg Gly 
                485                 490                 495     


Ile Ser Glu Ile Gln Ser Cys Ser Asp Pro Cys Met Glu Thr Glu Pro 
            500                 505                 510         


Ser Phe Glu Thr Gly Asp Leu Cys Asn Asp Thr Asn Pro Ala Pro Lys 
        515                 520                 525             


His Lys Ser Cys Gly Asp Pro Gly Pro Gly Asn Asp Thr Cys Gly Phe 
    530                 535                 540                 


His Ser Phe Phe Asn Thr Pro Tyr Asn Asn Phe Met Ser Tyr Ala Asp 
545                 550                 555                 560 


Asp Asp Cys Thr Asp Ser Phe Thr Pro Asn Gln Val Ala Arg Met His 
                565                 570                 575     


Cys Tyr Leu Asp Leu Val Tyr Gln Gly Trp Gln Pro Ser Arg Lys Pro 
            580                 585                 590         


Ala Pro Val Ala Leu Ala Pro Gln Val Leu Gly His Thr Thr Asp Ser 
        595                 600                 605             


Val Thr Leu Glu Trp Phe Pro Pro Ile Asp Gly His Phe Phe Glu Arg 
    610                 615                 620                 


Glu Leu Gly Ser Ala Cys His Leu Cys Leu Glu Gly Arg Ile Leu Val 
625                 630                 635                 640 


Gln Tyr Ala Ser Asn Ala Ser Ser Pro Met Pro Cys Ser Pro Ser Gly 
                645                 650                 655     


His Trp Ser Pro Arg Glu Ala Glu Gly His Pro Asp Val Glu Gln Pro 
            660                 665                 670         


Cys Lys Ser Ser Val Arg Thr Trp Ser Pro Asn Ser Ala Val Asn Pro 
        675                 680                 685             


His Thr Val Pro Pro Ala Cys Pro Glu Pro Gln Gly Cys Tyr Leu Glu 
    690                 695                 700                 


Leu Glu Phe Leu Tyr Pro Leu Val Pro Glu Ser Leu Thr Ile Trp Val 
705                 710                 715                 720 


Thr Phe Val Ser Thr Asp Trp Asp Ser Ser Gly Ala Val Asn Asp Ile 
                725                 730                 735     


Lys Leu Leu Ala Val Ser Gly Lys Asn Ile Ser Leu Gly Pro Gln Asn 
            740                 745                 750         


Val Phe Cys Asp Val Pro Leu Thr Ile Arg Leu Trp Asp Val Gly Glu 
        755                 760                 765             


Glu Val Tyr Gly Ile Gln Ile Tyr Thr Leu Asp Glu His Leu Glu Ile 
    770                 775                 780                 


Asp Ala Ala Met Leu Thr Ser Thr Ala Asp Thr Pro Leu Cys Leu Gln 
785                 790                 795                 800 


Cys Lys Pro Leu Lys Tyr Lys Val Val Arg Asp Pro Pro Leu Gln Met 
                805                 810                 815     


Asp Val Ala Ser Ile Leu His Leu Asn Arg Lys Phe Val Asp Met Asp 
            820                 825                 830         


Leu Asn Leu Gly Ser Val Tyr Gln Tyr Trp Val Ile Thr Ile Ser Gly 
        835                 840                 845             


Thr Glu Glu Ser Glu Pro Ser Pro Ala Val Thr Tyr Ile His Gly Ser 
    850                 855                 860                 


Gly Tyr Cys Gly Asp Gly Ile Ile Gln Lys Asp Gln Gly Glu Gln Cys 
865                 870                 875                 880 


Asp Asp Met Asn Lys Ile Asn Gly Asp Gly Cys Ser Leu Phe Cys Arg 
                885                 890                 895     


Gln Glu Val Ser Phe Asn Cys Ile Asp Glu Pro Ser Arg Cys Tyr Phe 
            900                 905                 910         


His Asp Gly Asp Gly Val Cys Glu Glu Phe Glu Gln Lys Thr Ser Ile 
        915                 920                 925             


Lys Asp Cys Gly Val Tyr Thr Pro Gln Gly Phe Leu Asp Gln Trp Ala 
    930                 935                 940                 


Ser Asn Ala Ser Val Ser His Gln Asp Gln Gln Cys Pro Gly Trp Val 
945                 950                 955                 960 


Ile Ile Gly Gln Pro Ala Ala Ser Gln Val Cys Arg Thr Lys Val Ile 
                965                 970                 975     


Asp Leu Ser Glu Gly Ile Ser Gln His Ala Trp Tyr Pro Cys Thr Ile 
            980                 985                 990         


Ser Tyr Pro Tyr Ser Gln Leu Ala  Gln Thr Thr Phe Trp  Leu Arg Ala 
        995                 1000                 1005             


Tyr Phe  Ser Gln Pro Met Val  Ala Ala Ala Val Ile  Val His Leu 
    1010                 1015                 1020             


Val Thr  Asp Gly Thr Tyr Tyr  Gly Asp Gln Lys Gln  Glu Thr Ile 
    1025                 1030                 1035             


Ser Val  Gln Leu Leu Asp Thr  Lys Asp Gln Ser His  Asp Leu Gly 
    1040                 1045                 1050             


Leu His  Val Leu Ser Cys Arg  Asn Asn Pro Leu Ile  Ile Pro Val 
    1055                 1060                 1065             


Val His  Asp Leu Ser Gln Pro  Phe Tyr His Ser Gln  Ala Val Arg 
    1070                 1075                 1080             


Val Ser  Phe Ser Ser Pro Leu  Val Ala Ile Ser Gly  Val Ala Leu 
    1085                 1090                 1095             


Arg Ser  Phe Asp Asn Phe Asp  Pro Val Thr Leu Ser  Ser Cys Gln 
    1100                 1105                 1110             


Arg Gly  Glu Thr Tyr Ser Pro  Ala Glu Gln Ser Cys  Val His Phe 
    1115                 1120                 1125             


Ala Cys  Glu Lys Thr Asp Cys  Pro Glu Leu Ala Val  Glu Asn Ala 
    1130                 1135                 1140             


Tyr Leu  Asn Cys Ser Ser Ser  Asp Arg Tyr His Gly  Ala Gln Cys 
    1145                 1150                 1155             


Thr Val  Ser Cys Arg Thr Gly  Tyr Val Leu Gln Ile  Arg Arg Asp 
    1160                 1165                 1170             


Asp Glu  Leu Ile Lys Ser Gln  Thr Gly Pro Ser Val  Thr Val Thr 
    1175                 1180                 1185             


Cys Thr  Glu Gly Lys Trp Asn  Lys Gln Val Ala Cys  Glu Pro Val 
    1190                 1195                 1200             


Asp Cys  Ser Ile Pro Asp His  His Gln Val Tyr Ala  Ala Ser Phe 
    1205                 1210                 1215             


Ser Cys  Pro Glu Gly Thr Thr  Phe Gly Ser Gln Cys  Ser Phe Gln 
    1220                 1225                 1230             


Cys Arg  His Pro Ala Gln Leu  Lys Gly Asn Asn Ser  Leu Leu Thr 
    1235                 1240                 1245             


Cys Met  Glu Asp Gly Leu Trp  Ser Phe Pro Glu Ala  Leu Cys Glu 
    1250                 1255                 1260             


Leu Met  Cys Leu Ala Pro Pro  Pro Val Pro Asn Ala  Asp Leu Gln 
    1265                 1270                 1275             


Thr Ala  Arg Cys Arg Glu Asn  Lys His Lys Val Gly  Ser Phe Cys 
    1280                 1285                 1290             


Lys Tyr  Lys Cys Lys Pro Gly  Tyr His Val Pro Gly  Ser Ser Arg 
    1295                 1300                 1305             


Lys Ser  Lys Lys Arg Ala Phe  Lys Thr Gln Cys Thr  Gln Asp Gly 
    1310                 1315                 1320             


Ser Trp  Gln Glu Gly Ala Cys  Val Pro Val Thr Cys  Asp Pro Pro 
    1325                 1330                 1335             


Pro Pro  Lys Phe His Gly Leu  Tyr Gln Cys Thr Asn  Gly Phe Gln 
    1340                 1345                 1350             


Phe Asn  Ser Glu Cys Arg Ile  Lys Cys Glu Asp Ser  Asp Ala Ser 
    1355                 1360                 1365             


Gln Gly  Leu Gly Ser Asn Val  Ile His Cys Arg Lys  Asp Gly Thr 
    1370                 1375                 1380             


Trp Asn  Gly Ser Phe His Val  Cys Gln Glu Met Gln  Gly Gln Cys 
    1385                 1390                 1395             


Ser Val  Pro Asn Glu Leu Asn  Ser Asn Leu Lys Leu  Gln Cys Pro 
    1400                 1405                 1410             


Asp Gly  Tyr Ala Ile Gly Ser  Glu Cys Ala Thr Ser  Cys Leu Asp 
    1415                 1420                 1425             


His Asn  Ser Glu Ser Ile Ile  Leu Pro Met Asn Val  Thr Val Arg 
    1430                 1435                 1440             


Asp Ile  Pro His Trp Leu Asn  Pro Thr Arg Val Glu  Arg Val Val 
    1445                 1450                 1455             


Cys Thr  Ala Gly Leu Lys Trp  Tyr Pro His Pro Ala  Leu Ile His 
    1460                 1465                 1470             


Cys Val  Lys Gly Cys Glu Pro  Phe Met Gly Asp Asn  Tyr Cys Asp 
    1475                 1480                 1485             


Ala Ile  Asn Asn Arg Ala Phe  Cys Asn Tyr Asp Gly  Gly Asp Cys 
    1490                 1495                 1500             


Cys Thr  Ser Thr Val Lys Thr  Lys Lys Val Thr Pro  Phe Pro Met 
    1505                 1510                 1515             


Ser Cys  Asp Leu Gln Gly Asp  Cys Ala Cys Arg Asp  Pro Gln Ala 
    1520                 1525                 1530             


Gln Glu  His Ser Arg Lys Asp  Leu Gln Gly Tyr Ser  His Gly 
    1535                 1540                 1545         


<210>  1042
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  1042

Ser Leu Ser Met Arg Asn Asp Ala Val Asn Glu Ile Val Ala Val Lys 
1               5                   10                  15      


Asn Asn Phe Pro Val Ile Glu Ile Val Gln Cys Arg Met Cys His Leu 
            20                  25                  30          


Gln Phe Pro Gly Glu Lys Cys Ser Arg Gly Arg Gly Ile Cys Thr Ala 
        35                  40                  45              


Thr Thr Glu Glu Ala Cys Met Val Gly Arg Met Phe Lys Arg Asp Gly 
    50                  55                  60                  


Asn Pro Trp Leu Thr Phe Met Gly Cys Leu Lys Asn Cys Ala Asp Val 
65                  70                  75                  80  


Lys Gly Ile Arg Trp Ser Val Tyr Leu Val Asn Phe Arg Cys Cys Arg 
                85                  90                  95      


Ser His Asp Leu Cys Asn Glu Asp Leu 
            100                 105 


<210>  1043
<211>  87
<212>  PRT
<213>  Homo Sapiens

<400>  1043

Thr Glu Ile Met Cys Tyr Glu Cys Lys Lys Tyr His Leu Gly Leu Cys 
1               5                   10                  15      


Tyr Gly Val Met Thr Ser Cys Ser Leu Lys His Lys Gln Ser Cys Ala 
            20                  25                  30          


Val Glu Asn Phe Tyr Ile Leu Thr Arg Lys Gly Gln Ser Met Tyr His 
        35                  40                  45              


Tyr Ser Lys Leu Ser Cys Met Thr Ser Cys Glu Asp Ile Asn Phe Leu 
    50                  55                  60                  


Gly Phe Thr Lys Arg Val Glu Leu Ile Cys Cys Asp His Ser Asn Tyr 
65                  70                  75                  80  


Cys Asn Leu Pro Glu Gly Val 
                85          


<210>  1044
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  1044

Leu Gln Cys Ile Thr Cys His Leu Arg Thr Arg Thr Asp Arg Cys Arg 
1               5                   10                  15      


Arg Gly Phe Gly Val Cys Thr Ala Gln Lys Gly Glu Ala Cys Met Leu 
            20                  25                  30          


Leu Arg Ile Tyr Gln Arg Asn Thr Leu Gln Ile Ser Tyr Met Val Cys 
        35                  40                  45              


Gln Lys Phe Cys Arg Asp Met Thr Phe Asp Leu Arg Asn Arg Thr Tyr 
    50                  55                  60                  


Val His Thr Cys Cys Asn Tyr Asn Tyr Cys Asn Phe Lys Leu 
65                  70                  75              


<210>  1045
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  1045

Leu Lys Cys Asn Thr Cys Ile Tyr Thr Glu Gly Trp Lys Cys Met Ala 
1               5                   10                  15      


Gly Arg Gly Thr Cys Ile Ala Lys Glu Asn Glu Leu Cys Ser Thr Thr 
            20                  25                  30          


Ala Tyr Phe Arg Gly Asp Lys His Met Tyr Ser Thr His Met Cys Lys 
        35                  40                  45              


Tyr Lys Cys Arg Glu Glu Glu Ser Ser Lys Arg Gly Leu Leu Arg Val 
    50                  55                  60                  


Thr Leu Cys Cys Asp Arg Asn Phe Cys Asn Val Phe 
65                  70                  75      


<210>  1046
<211>  697
<212>  PRT
<213>  Homo Sapiens

<400>  1046

Gln Leu His Tyr Thr Val Gln Glu Glu Gln Glu His Gly Thr Phe Val 
1               5                   10                  15      


Gly Asn Ile Ala Glu Asp Leu Gly Leu Asp Ile Thr Lys Leu Ser Ala 
            20                  25                  30          


Arg Gly Phe Gln Thr Val Pro Asn Ser Arg Thr Pro Tyr Leu Asp Leu 
        35                  40                  45              


Asn Leu Glu Thr Gly Val Leu Tyr Val Asn Glu Lys Ile Asp Arg Glu 
    50                  55                  60                  


Gln Ile Cys Lys Gln Ser Pro Ser Cys Val Leu His Leu Glu Val Phe 
65                  70                  75                  80  


Leu Glu Asn Pro Leu Glu Leu Phe Gln Val Glu Ile Glu Val Leu Asp 
                85                  90                  95      


Ile Asn Asp Asn Pro Pro Ser Phe Pro Glu Pro Asp Leu Thr Val Glu 
            100                 105                 110         


Ile Ser Glu Ser Ala Thr Pro Gly Thr Arg Phe Pro Leu Glu Ser Ala 
        115                 120                 125             


Phe Asp Pro Asp Val Gly Thr Asn Ser Leu Arg Asp Tyr Glu Ile Thr 
    130                 135                 140                 


Pro Asn Ser Tyr Phe Ser Leu Asp Val Gln Thr Gln Gly Asp Gly Asn 
145                 150                 155                 160 


Arg Phe Ala Glu Leu Val Leu Glu Lys Pro Leu Asp Arg Glu Gln Gln 
                165                 170                 175     


Ala Val His Arg Tyr Val Leu Thr Ala Val Asp Gly Gly Gly Gly Gly 
            180                 185                 190         


Gly Val Gly Glu Gly Gly Gly Gly Gly Gly Gly Ala Gly Leu Pro Pro 
        195                 200                 205             


Gln Gln Gln Arg Thr Gly Thr Ala Leu Leu Thr Ile Arg Val Leu Asp 
    210                 215                 220                 


Ser Asn Asp Asn Val Pro Ala Phe Asp Gln Pro Val Tyr Thr Val Ser 
225                 230                 235                 240 


Leu Pro Glu Asn Ser Pro Pro Gly Thr Leu Val Ile Gln Leu Asn Ala 
                245                 250                 255     


Thr Asp Pro Asp Glu Gly Gln Asn Gly Glu Val Val Tyr Ser Phe Ser 
            260                 265                 270         


Ser His Ile Ser Pro Arg Ala Arg Glu Leu Phe Gly Leu Ser Pro Arg 
        275                 280                 285             


Thr Gly Arg Leu Glu Val Ser Gly Glu Leu Asp Tyr Glu Glu Ser Pro 
    290                 295                 300                 


Val Tyr Gln Val Tyr Val Gln Ala Lys Asp Leu Gly Pro Asn Ala Val 
305                 310                 315                 320 


Pro Ala His Cys Lys Val Leu Val Arg Val Leu Asp Ala Asn Asp Asn 
                325                 330                 335     


Ala Pro Glu Ile Ser Phe Ser Thr Val Lys Glu Ala Val Ser Glu Gly 
            340                 345                 350         


Ala Ala Pro Gly Thr Val Val Ala Leu Phe Ser Val Thr Asp Arg Asp 
        355                 360                 365             


Ser Glu Glu Asn Gly Gln Val Gln Cys Glu Leu Leu Gly Asp Val Pro 
    370                 375                 380                 


Phe Arg Pro Lys Ser Ser Phe Lys Asn Tyr Tyr Thr Ile Val Thr Glu 
385                 390                 395                 400 


Ala Pro Leu Asp Arg Glu Ala Gly Asp Ser Tyr Thr Leu Thr Val Val 
                405                 410                 415     


Ala Arg Asp Arg Gly Glu Pro Ala Leu Ser Thr Ser Lys Ser Ile Gln 
            420                 425                 430         


Val Gln Val Ser Asp Val Asn Asp Asn Ala Pro Arg Phe Ser Gln Pro 
        435                 440                 445             


Val Tyr Asp Val Tyr Val Thr Glu Asn Asn Val Pro Gly Ala Tyr Ile 
    450                 455                 460                 


Tyr Ala Val Ser Ala Thr Asp Arg Asp Glu Gly Ala Asn Ala Gln Leu 
465                 470                 475                 480 


Ala Tyr Ser Ile Leu Glu Cys Gln Ile Gln Gly Met Ser Val Phe Thr 
                485                 490                 495     


Tyr Val Ser Ile Asn Ser Glu Asn Gly Tyr Leu Tyr Ala Leu Arg Ser 
            500                 505                 510         


Phe Asp Tyr Glu Gln Leu Lys Asp Phe Ser Phe Gln Val Glu Ala Arg 
        515                 520                 525             


Asp Ala Gly Ser Pro Gln Ala Leu Ala Gly Asn Ala Thr Val Asn Ile 
    530                 535                 540                 


Leu Ile Val Asp Gln Asn Asp Asn Ala Pro Ala Ile Val Ala Pro Leu 
545                 550                 555                 560 


Pro Gly Arg Asn Gly Thr Pro Ala Arg Glu Val Leu Pro Arg Ser Ala 
                565                 570                 575     


Glu Pro Gly Tyr Leu Leu Thr Arg Val Ala Ala Val Asp Ala Asp Asp 
            580                 585                 590         


Gly Glu Asn Ala Arg Leu Thr Tyr Ser Ile Val Arg Gly Asn Glu Met 
        595                 600                 605             


Asn Leu Phe Arg Met Asp Trp Arg Thr Gly Glu Leu Arg Thr Ala Arg 
    610                 615                 620                 


Arg Val Pro Ala Lys Arg Asp Pro Gln Arg Pro Tyr Glu Leu Val Ile 
625                 630                 635                 640 


Glu Val Arg Asp His Gly Gln Pro Pro Leu Ser Ser Thr Ala Thr Leu 
                645                 650                 655     


Val Val Gln Leu Val Asp Gly Ala Val Glu Pro Gln Gly Gly Gly Gly 
            660                 665                 670         


Ser Gly Gly Gly Gly Ser Gly Glu His Gln Arg Pro Ser Arg Ser Gly 
        675                 680                 685             


Gly Gly Glu Thr Ser Leu Asp Leu Thr 
    690                 695         


<210>  1047
<211>  694
<212>  PRT
<213>  Homo Sapiens

<400>  1047

Gln Glu Val Thr Thr Leu Thr Val Lys Tyr Gln Val Ser Glu Glu Val 
1               5                   10                  15      


Pro Ser Gly Thr Val Ile Gly Lys Leu Ser Gln Glu Leu Gly Arg Glu 
            20                  25                  30          


Glu Arg Arg Arg Gln Ala Gly Ala Ala Phe Gln Val Leu Gln Leu Pro 
        35                  40                  45              


Gln Ala Leu Pro Ile Gln Val Asp Ser Glu Glu Gly Leu Leu Ser Thr 
    50                  55                  60                  


Gly Arg Arg Leu Asp Arg Glu Gln Leu Cys Arg Gln Trp Asp Pro Cys 
65                  70                  75                  80  


Leu Val Ser Phe Asp Val Leu Ala Thr Gly Asp Leu Ala Leu Ile His 
                85                  90                  95      


Val Glu Ile Gln Val Leu Asp Ile Asn Asp His Gln Pro Arg Phe Pro 
            100                 105                 110         


Lys Gly Glu Gln Glu Leu Glu Ile Ser Glu Ser Ala Ser Leu Arg Thr 
        115                 120                 125             


Arg Ile Pro Leu Asp Arg Ala Leu Asp Pro Asp Thr Gly Pro Asn Thr 
    130                 135                 140                 


Leu His Thr Tyr Thr Leu Ser Pro Ser Glu His Phe Ala Leu Asp Val 
145                 150                 155                 160 


Ile Val Gly Pro Asp Glu Thr Lys His Ala Glu Leu Ile Val Val Lys 
                165                 170                 175     


Glu Leu Asp Arg Glu Ile His Ser Phe Phe Asp Leu Val Leu Thr Ala 
            180                 185                 190         


Tyr Asp Asn Gly Asn Pro Pro Lys Ser Gly Thr Ser Leu Val Lys Val 
        195                 200                 205             


Asn Val Leu Asp Ser Asn Asp Asn Ser Pro Ala Phe Ala Glu Ser Ser 
    210                 215                 220                 


Leu Ala Leu Glu Ile Gln Glu Asp Ala Ala Pro Gly Thr Leu Leu Ile 
225                 230                 235                 240 


Lys Leu Thr Ala Thr Asp Pro Asp Gln Gly Pro Asn Gly Glu Val Glu 
                245                 250                 255     


Phe Phe Leu Ser Lys His Met Pro Pro Glu Val Leu Asp Thr Phe Ser 
            260                 265                 270         


Ile Asp Ala Lys Thr Gly Gln Val Ile Leu Arg Arg Pro Leu Asp Tyr 
        275                 280                 285             


Glu Lys Asn Pro Ala Tyr Glu Val Asp Val Gln Ala Arg Asp Leu Gly 
    290                 295                 300                 


Pro Asn Pro Ile Pro Ala His Cys Lys Val Leu Ile Lys Val Leu Asp 
305                 310                 315                 320 


Val Asn Asp Asn Ile Pro Ser Ile His Val Thr Trp Ala Ser Gln Pro 
                325                 330                 335     


Ser Leu Val Ser Glu Ala Leu Pro Lys Asp Ser Phe Ile Ala Leu Val 
            340                 345                 350         


Met Ala Asp Asp Leu Asp Ser Gly Asn Asn Gly Leu Val His Cys Trp 
        355                 360                 365             


Leu Ser Gln Glu Leu Gly His Phe Arg Leu Lys Arg Thr Asn Gly Asn 
    370                 375                 380                 


Thr Tyr Met Leu Leu Thr Asn Ala Thr Leu Asp Arg Glu Gln Trp Pro 
385                 390                 395                 400 


Lys Tyr Thr Leu Thr Leu Leu Ala Gln Asp Gln Gly Leu Gln Pro Leu 
                405                 410                 415     


Ser Ala Lys Lys Gln Leu Ser Ile Gln Ile Ser Asp Ile Asn Asp Asn 
            420                 425                 430         


Ala Pro Val Phe Glu Lys Ser Arg Tyr Glu Val Ser Thr Arg Glu Asn 
        435                 440                 445             


Asn Leu Pro Ser Leu His Leu Ile Thr Ile Lys Ala His Asp Ala Asp 
    450                 455                 460                 


Leu Gly Ile Asn Gly Lys Val Ser Tyr Arg Ile Gln Asp Ser Pro Val 
465                 470                 475                 480 


Ala His Leu Val Ala Ile Asp Ser Asn Thr Gly Glu Val Thr Ala Gln 
                485                 490                 495     


Arg Ser Leu Asn Tyr Glu Glu Met Ala Gly Phe Glu Phe Gln Val Ile 
            500                 505                 510         


Ala Glu Asp Ser Gly Gln Pro Met Leu Ala Ser Ser Val Ser Val Trp 
        515                 520                 525             


Val Ser Leu Leu Asp Ala Asn Asp Asn Ala Pro Glu Val Val Gln Pro 
    530                 535                 540                 


Val Leu Ser Asp Gly Lys Ala Ser Leu Ser Val Leu Val Asn Ala Ser 
545                 550                 555                 560 


Thr Gly His Leu Leu Val Pro Ile Glu Thr Pro Asn Gly Leu Gly Pro 
                565                 570                 575     


Ala Gly Thr Asp Thr Pro Pro Leu Ala Thr His Ser Ser Arg Pro Phe 
            580                 585                 590         


Leu Leu Thr Thr Ile Val Ala Arg Asp Ala Asp Ser Gly Ala Asn Gly 
        595                 600                 605             


Glu Pro Leu Tyr Ser Ile Arg Ser Gly Asn Glu Ala His Leu Phe Ile 
    610                 615                 620                 


Leu Asn Pro His Thr Gly Gln Leu Phe Val Asn Val Thr Asn Ala Ser 
625                 630                 635                 640 


Ser Leu Ile Gly Ser Glu Trp Glu Leu Glu Ile Val Val Glu Asp Gln 
                645                 650                 655     


Gly Ser Pro Pro Leu Gln Thr Arg Ala Leu Leu Arg Val Met Phe Val 
            660                 665                 670         


Thr Ser Val Asp His Leu Arg Asp Ser Ala Arg Lys Pro Gly Ala Leu 
        675                 680                 685             


Ser Met Ser Met Leu Thr 
    690                 


<210>  1048
<211>  830
<212>  PRT
<213>  Homo Sapiens

<400>  1048

Ser Tyr Ser Arg Ala Thr Glu Leu Leu Tyr Ser Leu Asn Glu Gly Leu 
1               5                   10                  15      


Pro Ala Gly Val Leu Ile Gly Ser Leu Ala Glu Asp Leu Arg Leu Leu 
            20                  25                  30          


Pro Arg Ser Ala Gly Arg Pro Asp Pro Gln Ser Gln Leu Pro Glu Arg 
        35                  40                  45              


Thr Gly Ala Glu Trp Asn Pro Pro Leu Ser Phe Ser Leu Ala Ser Arg 
    50                  55                  60                  


Gly Leu Ser Gly Gln Tyr Val Thr Leu Asp Asn Arg Ser Gly Glu Leu 
65                  70                  75                  80  


His Thr Ser Ala Gln Glu Ile Asp Arg Glu Ala Leu Cys Val Glu Gly 
                85                  90                  95      


Gly Gly Gly Thr Ala Trp Ser Gly Ser Val Ser Ile Ser Ser Ser Pro 
            100                 105                 110         


Ser Asp Ser Cys Leu Leu Leu Leu Asp Val Leu Val Leu Pro Gln Glu 
        115                 120                 125             


Tyr Phe Arg Phe Val Lys Val Lys Ile Ala Ile Arg Asp Ile Asn Asp 
    130                 135                 140                 


Asn Ala Pro Gln Phe Pro Val Ser Gln Ile Ser Val Trp Val Pro Glu 
145                 150                 155                 160 


Asn Ala Pro Val Asn Thr Arg Leu Ala Ile Glu His Pro Ala Val Asp 
                165                 170                 175     


Pro Asp Val Gly Ile Asn Gly Val Gln Thr Tyr Arg Leu Leu Asp Tyr 
            180                 185                 190         


His Gly Met Phe Thr Leu Asp Val Glu Glu Asn Glu Asn Gly Glu Arg 
        195                 200                 205             


Thr Pro Tyr Leu Ile Val Met Gly Ala Leu Asp Arg Glu Thr Gln Asp 
    210                 215                 220                 


Gln Tyr Val Ser Ile Ile Ile Ala Glu Asp Gly Gly Ser Pro Pro Leu 
225                 230                 235                 240 


Leu Gly Ser Ala Thr Leu Thr Ile Gly Ile Ser Asp Ile Asn Asp Asn 
                245                 250                 255     


Cys Pro Leu Phe Thr Asp Ser Gln Ile Asn Val Thr Val Tyr Gly Asn 
            260                 265                 270         


Ala Thr Val Gly Thr Pro Ile Ala Ala Val Gln Ala Val Asp Lys Asp 
        275                 280                 285             


Leu Gly Thr Asn Ala Gln Ile Thr Tyr Ser Tyr Ser Gln Lys Val Pro 
    290                 295                 300                 


Gln Ala Ser Lys Asp Leu Phe His Leu Asp Glu Asn Thr Gly Val Ile 
305                 310                 315                 320 


Lys Leu Phe Ser Lys Ile Gly Gly Ser Val Leu Glu Ser His Lys Leu 
                325                 330                 335     


Thr Ile Leu Ala Asn Gly Pro Gly Cys Ile Pro Ala Val Ile Thr Ala 
            340                 345                 350         


Leu Val Ser Ile Ile Lys Val Ile Phe Arg Pro Pro Glu Ile Val Pro 
        355                 360                 365             


Arg Tyr Ile Ala Asn Glu Ile Asp Gly Val Val Tyr Leu Lys Glu Leu 
    370                 375                 380                 


Glu Pro Val Asn Thr Pro Ile Ala Phe Phe Thr Ile Arg Asp Pro Glu 
385                 390                 395                 400 


Gly Lys Tyr Lys Val Asn Cys Tyr Leu Asp Gly Glu Gly Pro Phe Arg 
                405                 410                 415     


Leu Ser Pro Tyr Lys Pro Tyr Asn Asn Glu Tyr Leu Leu Glu Thr Thr 
            420                 425                 430         


Lys Pro Met Asp Tyr Glu Leu Gln Gln Phe Tyr Glu Val Ala Val Val 
        435                 440                 445             


Ala Trp Asn Ser Glu Gly Phe His Val Lys Arg Val Ile Lys Val Gln 
    450                 455                 460                 


Leu Leu Asp Asp Asn Asp Asn Ala Pro Ile Phe Leu Gln Pro Leu Ile 
465                 470                 475                 480 


Glu Leu Thr Ile Glu Glu Asn Asn Ser Pro Asn Ala Phe Leu Thr Lys 
                485                 490                 495     


Leu Tyr Ala Thr Asp Ala Asp Ser Glu Glu Arg Gly Gln Val Ser Tyr 
            500                 505                 510         


Phe Leu Gly Pro Asp Ala Pro Ser Tyr Phe Ser Leu Asp Ser Val Thr 
        515                 520                 525             


Gly Ile Leu Thr Val Ser Thr Gln Leu Asp Arg Glu Glu Lys Glu Lys 
    530                 535                 540                 


Tyr Arg Tyr Thr Val Arg Ala Val Asp Cys Gly Lys Pro Pro Arg Glu 
545                 550                 555                 560 


Ser Val Ala Thr Val Ala Leu Thr Val Leu Asp Lys Asn Asp Asn Ser 
                565                 570                 575     


Pro Arg Phe Ile Asn Lys Asp Phe Ser Phe Phe Val Pro Glu Asn Phe 
            580                 585                 590         


Pro Gly Tyr Gly Glu Ile Gly Val Ile Ser Val Thr Asp Ala Asp Ala 
        595                 600                 605             


Gly Arg Asn Gly Trp Val Ala Leu Ser Val Val Asn Gln Ser Asp Ile 
    610                 615                 620                 


Phe Val Ile Asp Thr Gly Lys Gly Met Leu Arg Ala Lys Val Ser Leu 
625                 630                 635                 640 


Asp Arg Glu Gln Gln Ser Ser Tyr Thr Leu Trp Val Glu Ala Val Asp 
                645                 650                 655     


Gly Gly Glu Pro Ala Leu Ser Ser Thr Ala Lys Ile Thr Ile Leu Leu 
            660                 665                 670         


Leu Asp Ile Asn Asp Asn Pro Pro Leu Val Leu Phe Pro Gln Ser Asn 
        675                 680                 685             


Met Ser Tyr Leu Leu Val Leu Pro Ser Thr Leu Pro Gly Ser Pro Val 
    690                 695                 700                 


Thr Glu Val Tyr Ala Val Asp Lys Asp Thr Gly Met Asn Ala Val Ile 
705                 710                 715                 720 


Ala Tyr Ser Ile Ile Gly Arg Arg Gly Pro Arg Pro Glu Ser Phe Arg 
                725                 730                 735     


Ile Asp Pro Lys Thr Gly Asn Ile Thr Leu Glu Glu Ala Leu Leu Gln 
            740                 745                 750         


Thr Asp Tyr Gly Leu His Arg Leu Leu Val Lys Val Ser Asp His Gly 
        755                 760                 765             


Tyr Pro Glu Pro Leu His Ser Thr Val Met Val Asn Leu Phe Val Asn 
    770                 775                 780                 


Asp Thr Val Ser Asn Glu Ser Tyr Ile Glu Ser Leu Leu Arg Lys Glu 
785                 790                 795                 800 


Pro Glu Ile Asn Ile Glu Glu Lys Glu Pro Gln Ile Ser Ile Glu Pro 
                805                 810                 815     


Thr His Arg Lys Val Glu Ser Val Ser Cys Met Pro Thr Leu 
            820                 825                 830 


<210>  1049
<211>  791
<212>  PRT
<213>  Homo Sapiens

<400>  1049

Gln Glu Leu Ile Tyr Thr Ile Arg Glu Glu Leu Pro Glu Asn Val Pro 
1               5                   10                  15      


Ile Gly Asn Ile Pro Lys Asp Leu Asn Ile Ser His Ile Asn Ala Ala 
            20                  25                  30          


Thr Gly Thr Ser Ala Ser Leu Val Tyr Arg Leu Val Ser Lys Ala Gly 
        35                  40                  45              


Asp Ala Pro Leu Val Lys Val Ser Ser Ser Thr Gly Glu Ile Phe Thr 
    50                  55                  60                  


Thr Ser Asn Arg Ile Asp Arg Glu Lys Leu Cys Ala Gly Ala Ser Tyr 
65                  70                  75                  80  


Ala Glu Glu Asn Glu Cys Phe Phe Glu Leu Glu Val Val Ile Leu Pro 
                85                  90                  95      


Asn Asp Phe Phe Arg Leu Ile Lys Ile Lys Ile Ile Val Lys Asp Thr 
            100                 105                 110         


Asn Asp Asn Ala Pro Met Phe Pro Ser Pro Val Ile Asn Ile Ser Ile 
        115                 120                 125             


Pro Glu Asn Thr Leu Ile Asn Ser Arg Phe Pro Ile Pro Ser Ala Thr 
    130                 135                 140                 


Asp Pro Asp Thr Gly Phe Asn Gly Val Gln His Tyr Glu Leu Leu Asn 
145                 150                 155                 160 


Gly Gln Ser Val Phe Gly Leu Asp Ile Val Glu Thr Pro Glu Gly Glu 
                165                 170                 175     


Lys Trp Pro Gln Leu Ile Val Gln Gln Asn Leu Asp Arg Glu Gln Lys 
            180                 185                 190         


Asp Thr Tyr Val Met Lys Ile Lys Val Glu Asp Gly Gly Thr Pro Gln 
        195                 200                 205             


Lys Ser Ser Thr Ala Ile Leu Gln Val Thr Val Ser Asp Val Asn Asp 
    210                 215                 220                 


Asn Arg Pro Val Phe Lys Glu Gly Gln Val Glu Val His Ile Pro Glu 
225                 230                 235                 240 


Asn Ala Pro Val Gly Thr Ser Val Ile Gln Leu His Ala Thr Asp Ala 
                245                 250                 255     


Asp Ile Gly Ser Asn Ala Glu Ile Arg Tyr Ile Phe Gly Ala Gln Val 
            260                 265                 270         


Ala Pro Ala Thr Lys Arg Leu Phe Ala Leu Asn Asn Thr Thr Gly Leu 
        275                 280                 285             


Ile Thr Val Gln Arg Ser Leu Asp Arg Glu Glu Thr Ala Ile His Lys 
    290                 295                 300                 


Val Thr Val Leu Ala Ser Asp Gly Ser Ser Thr Pro Ala Arg Ala Thr 
305                 310                 315                 320 


Val Thr Ile Asn Val Thr Asp Val Asn Asp Asn Pro Pro Asn Ile Asp 
                325                 330                 335     


Leu Arg Tyr Ile Ile Ser Pro Ile Asn Gly Thr Val Tyr Leu Ser Glu 
            340                 345                 350         


Lys Asp Pro Val Asn Thr Lys Ile Ala Leu Ile Thr Val Ser Asp Lys 
        355                 360                 365             


Asp Thr Asp Val Asn Gly Lys Val Ile Cys Phe Ile Glu Arg Glu Val 
    370                 375                 380                 


Pro Phe His Leu Lys Ala Val Tyr Asp Asn Gln Tyr Leu Leu Glu Thr 
385                 390                 395                 400 


Ser Ser Leu Leu Asp Tyr Glu Gly Thr Lys Glu Phe Ser Phe Lys Ile 
                405                 410                 415     


Val Ala Ser Asp Ser Gly Lys Pro Ser Leu Asn Gln Thr Ala Leu Val 
            420                 425                 430         


Arg Val Lys Leu Glu Asp Glu Asn Asp Asn Pro Pro Ile Phe Asn Gln 
        435                 440                 445             


Pro Val Ile Glu Leu Ser Val Ser Glu Asn Asn Arg Arg Gly Leu Tyr 
    450                 455                 460                 


Leu Thr Thr Ile Ser Ala Thr Asp Glu Asp Ser Gly Lys Asn Ala Asp 
465                 470                 475                 480 


Ile Val Tyr Gln Leu Gly Pro Asn Ala Ser Phe Phe Asp Leu Asp Arg 
                485                 490                 495     


Lys Thr Gly Val Leu Thr Ala Ser Arg Val Phe Asp Arg Glu Glu Gln 
            500                 505                 510         


Glu Arg Phe Ile Phe Thr Val Thr Ala Arg Asp Asn Gly Thr Pro Pro 
        515                 520                 525             


Leu Gln Ser Gln Ala Ala Val Ile Val Thr Val Leu Asp Glu Asn Asp 
    530                 535                 540                 


Asn Ser Pro Lys Phe Thr His Asn His Phe Gln Phe Phe Val Ser Glu 
545                 550                 555                 560 


Asn Leu Pro Lys Tyr Ser Thr Val Gly Val Ile Thr Val Thr Asp Ala 
                565                 570                 575     


Asp Ala Gly Glu Asn Lys Ala Val Thr Leu Ser Ile Leu Asn Asp Asn 
            580                 585                 590         


Asp Asn Phe Val Leu Asp Pro Tyr Ser Gly Val Ile Lys Ser Asn Val 
        595                 600                 605             


Ser Phe Asp Arg Glu Gln Gln Ser Ser Tyr Thr Phe Asp Val Lys Ala 
    610                 615                 620                 


Thr Asp Gly Gly Gln Pro Pro Arg Ser Ser Thr Ala Lys Val Thr Ile 
625                 630                 635                 640 


Asn Val Met Asp Val Asn Asp Asn Ser Pro Val Val Ile Ser Pro Pro 
                645                 650                 655     


Ser Asn Thr Ser Phe Lys Leu Val Pro Leu Ser Ala Ile Pro Gly Ser 
            660                 665                 670         


Val Val Ala Glu Val Phe Ala Val Asp Val Asp Thr Gly Met Asn Ala 
        675                 680                 685             


Glu Leu Lys Tyr Thr Ile Val Ser Gly Asn Asn Lys Gly Leu Phe Arg 
    690                 695                 700                 


Ile Asp Pro Val Thr Gly Asn Ile Thr Leu Glu Glu Lys Pro Ala Pro 
705                 710                 715                 720 


Thr Asp Val Gly Leu His Arg Leu Val Val Asn Ile Ser Asp Leu Gly 
                725                 730                 735     


Tyr Pro Lys Ser Leu His Thr Leu Val Leu Val Phe Leu Tyr Val Asn 
            740                 745                 750         


Asp Thr Ala Gly Asn Ala Ser Tyr Ile Tyr Asp Leu Ile Arg Arg Thr 
        755                 760                 765             


Met Glu Thr Pro Leu Asp Arg Asn Ile Gly Asp Ser Ser Gln Pro Tyr 
    770                 775                 780                 


Gln Asn Glu Asp Tyr Leu Thr 
785                 790     


<210>  1050
<211>  668
<212>  PRT
<213>  Homo Sapiens

<400>  1050

Gln Leu His Tyr Ser Val Pro Glu Glu Ala Glu His Gly Thr Phe Val 
1               5                   10                  15      


Gly Arg Ile Ala Gln Asp Leu Gly Leu Glu Leu Ala Glu Leu Val Pro 
            20                  25                  30          


Arg Leu Phe Gln Leu Asp Ser Lys Gly Arg Gly Asp Leu Leu Glu Val 
        35                  40                  45              


Asn Leu Gln Asn Gly Ile Leu Phe Val Asn Ser Arg Ile Asp Arg Glu 
    50                  55                  60                  


Glu Leu Cys Gly Arg Ser Ala Glu Cys Ser Ile His Leu Glu Val Ile 
65                  70                  75                  80  


Val Asp Arg Pro Leu Gln Val Phe His Val Asp Val Glu Val Lys Asp 
                85                  90                  95      


Ile Asn Asp Asn Pro Pro Val Phe Pro Ala Thr Gln Lys Asn Leu Phe 
            100                 105                 110         


Ile Ala Glu Ser Arg Pro Leu Asp Ser Arg Phe Pro Leu Glu Gly Ala 
        115                 120                 125             


Ser Asp Ala Asp Ile Gly Glu Asn Ala Leu Leu Thr Tyr Arg Leu Ser 
    130                 135                 140                 


Pro Asn Glu Tyr Phe Phe Leu Asp Val Pro Thr Ser Asn Gln Gln Val 
145                 150                 155                 160 


Lys Pro Leu Gly Leu Val Leu Arg Lys Leu Leu Asp Arg Glu Glu Thr 
                165                 170                 175     


Pro Glu Leu His Leu Leu Leu Thr Ala Thr Asp Gly Gly Lys Pro Glu 
            180                 185                 190         


Leu Thr Gly Thr Val Gln Leu Leu Ile Thr Val Leu Asp Asn Asn Asp 
        195                 200                 205             


Asn Ala Pro Val Phe Asp Arg Thr Leu Tyr Thr Val Lys Leu Pro Glu 
    210                 215                 220                 


Asn Val Ser Ile Gly Thr Leu Val Ile His Pro Asn Ala Ser Asp Leu 
225                 230                 235                 240 


Asp Glu Gly Leu Asn Gly Asp Ile Ile Tyr Ser Phe Ser Ser Asp Val 
                245                 250                 255     


Ser Pro Asp Ile Lys Ser Lys Phe His Met Asp Pro Leu Ser Gly Ala 
            260                 265                 270         


Ile Thr Val Ile Gly His Met Asp Phe Glu Glu Ser Arg Ala His Lys 
        275                 280                 285             


Ile Pro Val Glu Ala Val Asp Lys Gly Phe Pro Pro Leu Ala Gly His 
    290                 295                 300                 


Cys Thr Leu Leu Val Glu Val Val Asp Val Asn Asp Asn Ala Pro Gln 
305                 310                 315                 320 


Leu Thr Ile Lys Thr Leu Ser Val Pro Val Lys Glu Asp Ala Gln Leu 
                325                 330                 335     


Gly Thr Val Ile Ala Leu Ile Ser Val Ile Asp Leu Asp Ala Asp Ala 
            340                 345                 350         


Asn Gly Gln Val Thr Cys Ser Leu Thr Pro His Val Pro Phe Lys Leu 
        355                 360                 365             


Val Ser Thr Tyr Lys Asn Tyr Tyr Ser Leu Val Leu Asp Arg Ala Leu 
    370                 375                 380                 


Asp Arg Glu Ser Val Ser Ala Tyr Glu Leu Val Val Thr Ala Arg Asp 
385                 390                 395                 400 


Gly Gly Ser Pro Ser Leu Trp Ala Thr Ala Arg Val Ser Val Glu Val 
                405                 410                 415     


Ala Asp Val Asn Asp Asn Ala Pro Ala Phe Ala Gln Ser Glu Tyr Thr 
            420                 425                 430         


Val Phe Val Lys Glu Asn Asn Pro Pro Gly Cys His Ile Phe Thr Val 
        435                 440                 445             


Ser Ala Arg Asp Ala Asp Ala Gln Glu Asn Ala Leu Val Ser Tyr Ser 
    450                 455                 460                 


Leu Val Glu Arg Arg Leu Gly Glu Arg Ser Leu Ser Ser Tyr Val Ser 
465                 470                 475                 480 


Val His Ala Glu Ser Gly Lys Val Tyr Ala Leu Gln Pro Leu Asp His 
                485                 490                 495     


Glu Glu Leu Glu Leu Leu Gln Phe Gln Val Ser Ala Arg Asp Ala Gly 
            500                 505                 510         


Val Pro Pro Leu Gly Ser Asn Val Thr Leu Gln Val Phe Val Leu Asp 
        515                 520                 525             


Glu Asn Asp Asn Ala Pro Ala Leu Leu Thr Pro Arg Met Arg Gly Thr 
    530                 535                 540                 


Asp Gly Ala Val Ser Glu Met Val Leu Arg Ser Val Gly Ala Gly Val 
545                 550                 555                 560 


Val Val Gly Lys Val Arg Ala Val Asp Ala Asp Ser Gly Tyr Asn Ala 
                565                 570                 575     


Trp Leu Ser Tyr Glu Leu Gln Pro Glu Thr Ala Ser Ala Ser Ile Pro 
            580                 585                 590         


Phe Arg Val Gly Leu Tyr Thr Gly Glu Ile Ser Thr Thr Arg Ala Leu 
        595                 600                 605             


Asp Glu Thr Asp Ala Pro Arg Gln Arg Leu Leu Val Leu Val Lys Asp 
    610                 615                 620                 


His Gly Glu Pro Ala Leu Thr Ala Thr Ala Thr Val Leu Val Ser Leu 
625                 630                 635                 640 


Val Glu Ser Gly Gln Ala Pro Lys Ser Ser Ser Arg Ala Ser Val Gly 
                645                 650                 655     


Ala Thr Gly Pro Glu Val Thr Leu Val Asp Val Asn 
            660                 665             


<210>  1051
<211>  663
<212>  PRT
<213>  Homo Sapiens

<400>  1051

Thr Thr Ile Arg Tyr Ser Val Ala Glu Glu Met Glu Ser Gly Ser Phe 
1               5                   10                  15      


Val Ala Asn Val Ala Lys Asp Leu Gly Leu Glu Val Gly Lys Leu Ala 
            20                  25                  30          


Ala Arg Gly Ala Arg Leu Val Ser Glu Gly Asn Lys Met His Phe Arg 
        35                  40                  45              


Leu His Arg Lys Thr Gly Asp Leu Phe Val Lys Glu Lys Leu Asp Arg 
    50                  55                  60                  


Glu Ser Leu Cys Gly Lys Ala Asp Pro Cys Val Leu His Phe Glu Val 
65                  70                  75                  80  


Val Leu Val Glu Pro Leu Gln Ser Phe Arg Ala Glu Val Arg Val Phe 
                85                  90                  95      


Asp Ile Asn Asp Asn Ala Pro Val Phe Leu Asn Lys Glu Pro Leu Leu 
            100                 105                 110         


Lys Ile Pro Glu Ser Thr Pro Leu Gly Ser Arg Phe Pro Leu Gln Ser 
        115                 120                 125             


Ala Gln Asp Leu Asp Val Gly Leu Asn Gly Leu Gln Asn Tyr Thr Leu 
    130                 135                 140                 


Ser Ala Asn Gly Tyr Phe His Leu His Thr Arg Phe Cys Ser His Gly 
145                 150                 155                 160 


Pro Lys Tyr Ala Glu Leu Val Leu Asn Lys Pro Leu Asp Arg Glu Glu 
                165                 170                 175     


Gln Pro Glu Val Asn Leu Thr Ile Thr Ala Val Asp Gly Gly Ser Pro 
            180                 185                 190         


Pro Lys Ser Gly Thr Ala His Ile His Val Val Val Leu Asp Val Asn 
        195                 200                 205             


Asp His Val Pro Gln Phe Ser Arg Leu Val Tyr Arg Ala Gln Val Ser 
    210                 215                 220                 


Glu Asn Ser Pro Asn Gly Ser Leu Val Ala Thr Val Thr Ala Val Asp 
225                 230                 235                 240 


Leu Asp Glu Gly Thr Asn Lys Ala Ile Thr Tyr Ser Leu Ala Gln Asn 
                245                 250                 255     


Pro Glu Ala Ile Leu Lys Thr Phe Gln Ile Asp Pro Gln Asn Gly Glu 
            260                 265                 270         


Val Arg Leu Arg Gly Pro Leu Asp Phe Glu Ala Ile Glu Thr Tyr Asp 
        275                 280                 285             


Ile Asp Ile Gln Ala Thr Asp Gly Gly Gly Leu Ser Ala His Ser Lys 
    290                 295                 300                 


Val Leu Val Glu Val Val Asp Val Asn Asp Asn Pro Pro Glu Val Met 
305                 310                 315                 320 


Val Ser Ser Val Ser Ser Pro Leu Pro Glu Asp Ser Pro Pro Gln Thr 
                325                 330                 335     


Val Val Ala Leu Phe Thr Ile Arg Asp Arg Asp Ile Arg Val Gly Gly 
            340                 345                 350         


Lys Val Thr Cys Phe Leu Arg Glu Asp Leu Pro Phe Val Ile Lys Pro 
        355                 360                 365             


Thr Phe Gly Asn Ser Tyr Ser Leu Val Thr Asp Arg Ser Leu Asp Arg 
    370                 375                 380                 


Glu Glu Val Ser Gly Tyr Asn Ile Thr Ile Val Ala Met Asp Thr Gly 
385                 390                 395                 400 


Pro Pro Ser Leu Ser Ala Glu Thr Met Ile Glu Val Leu Ile Ser Asp 
                405                 410                 415     


Val Asn Asp Asn Pro Pro Ile Phe Arg Glu Asp Ser Tyr Ile Leu Thr 
            420                 425                 430         


Val Arg Glu Asn Asn Ser Pro Ala Val Phe Ile Gly Lys Val His Ala 
        435                 440                 445             


Glu Asp Leu Asp Leu Gly Glu Asn Ala Gln Ile Thr Tyr Ser Leu Leu 
    450                 455                 460                 


Pro Pro Lys Asn Gly Asp Leu Ser Val Phe Ala Tyr Ile Ser Ile Asn 
465                 470                 475                 480 


Ser Gly Asn Gly Lys Leu Tyr Ala Leu Arg Thr Met Asp Tyr Glu Ala 
                485                 490                 495     


Ile Gln Asp Phe Gln Phe Val Val Lys Ala Thr Asp Gly Gly Phe Leu 
            500                 505                 510         


Ser Leu Ser Ser Gln Val Thr Val Arg Val Val Val Leu Asp Asp Asn 
        515                 520                 525             


Asp Asn Arg Pro Met Ile Leu Tyr Pro Leu Gln Asn Gly Thr Leu Pro 
    530                 535                 540                 


Cys Asn Asp Leu Val Pro Arg Ser Ala Glu Ala Gly Tyr Leu Val Thr 
545                 550                 555                 560 


Lys Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ser Trp Leu Ser 
                565                 570                 575     


Tyr His Leu Leu Lys Ala Thr Asp Leu Gly Leu Phe Ser Val Gln Arg 
            580                 585                 590         


Gln Asn Gly Glu Ile His Thr Leu Arg Gln Ile Ser Glu Arg Asp Pro 
        595                 600                 605             


Met Met Gln Lys Leu Ile Ile Leu Val Gln Asp His Gly Gln Pro Ala 
    610                 615                 620                 


Leu Ser Thr Thr Val Ser Leu Asn Ile Leu Leu Val Asp Gly Phe Ser 
625                 630                 635                 640 


Glu Pro Tyr Leu Gln Phe Gln Asp Pro Thr Lys His Ser Arg Lys Val 
                645                 650                 655     


Asn Pro Ser Thr Lys Tyr Leu 
            660             


<210>  1052
<211>  664
<212>  PRT
<213>  Homo Sapiens

<400>  1052

Gly Ser Glu Thr Trp Ser Phe Ser Val Ala Glu Glu Met Gln Ser Gly 
1               5                   10                  15      


Ser Phe Val Gly Asn Leu Ala Lys Asp Leu Gly Leu Lys Val Arg Glu 
            20                  25                  30          


Leu Ser Ser Arg Gly Ala Arg Val Val Ser Asn Asp Lys Lys Gln Arg 
        35                  40                  45              


Leu Gln Leu Asp Ile Asn Thr Gly Asp Leu Leu Leu Ser Glu Thr Leu 
    50                  55                  60                  


Asp Arg Glu Glu Leu Cys Gly Ser Ile Glu Pro Cys Val Leu His Leu 
65                  70                  75                  80  


Gln Val Leu Met Gln Asn Pro Thr Gln Phe Leu Gln Ile Glu Leu Gln 
                85                  90                  95      


Val Arg Asp Ile Asn Asp His Ser Pro Ile Phe Ser Glu Lys Gln Met 
            100                 105                 110         


Leu Leu Glu Ile Pro Glu Asn Ser Pro Val Gly Ala Val Phe Leu Leu 
        115                 120                 125             


Glu Ser Ala Lys Asp Leu Asp Val Gly Ile Asn Ala Val Lys Ser Tyr 
    130                 135                 140                 


Thr Ile Ser Pro Asn Ser His Phe His Ile Lys Met Arg Val Ile Pro 
145                 150                 155                 160 


Asp Asn Arg Lys Tyr Pro Glu Leu Val Leu Asp Lys Ala Leu Asp Tyr 
                165                 170                 175     


Glu Glu Leu Pro Glu Leu Ser Phe Ile Leu Ser Ala Leu Asp Gly Gly 
            180                 185                 190         


Ser Pro Pro Arg Ser Gly Thr Ala Leu Val Arg Val Val Val Val Asp 
        195                 200                 205             


Ile Asn Asp Asn Ser Pro Glu Phe Glu Gln Ala Phe Tyr Glu Val Lys 
    210                 215                 220                 


Ile Arg Glu Asn Ser Ile Leu Gly Ser Leu Ile Leu Ile Val Ser Ala 
225                 230                 235                 240 


Trp Asp Leu Asp Ser Gly Thr Asn Gly Glu Ile Cys Tyr Thr Phe Ser 
                245                 250                 255     


His Ala Ser Glu Asp Ile Arg Lys Thr Phe Glu Ile Asn Gln Lys Ser 
            260                 265                 270         


Gly Glu Ile Thr Leu Arg Ala Pro Leu Asp Phe Glu Thr Ile Glu Ser 
        275                 280                 285             


Tyr Ser Ile Ile Ile Gln Ala Thr Asp Gly Gly Gly Leu Phe Gly Lys 
    290                 295                 300                 


Ser Thr Val Ile Ile His Val Ile Asp Val Asn Asp Asn Ala Pro Glu 
305                 310                 315                 320 


Ile Thr Val Ser Ser Ile Thr Ser Pro Ile Pro Glu Asn Thr Pro Glu 
                325                 330                 335     


Thr Val Val Met Val Phe Ser Ile Gln Asp Ile Asp Ser Gly Asp Asn 
            340                 345                 350         


Gly Arg Ile Val Cys Ser Ile Pro Glu Asp Leu Pro Phe Val Leu Lys 
        355                 360                 365             


Ser Ser Val Glu Asn Tyr Tyr Thr Leu Glu Thr Glu Arg Pro Leu Asp 
    370                 375                 380                 


Arg Glu Ser Thr Ala Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu 
385                 390                 395                 400 


Gly Ile Pro Arg Leu Lys Thr Glu His Asn Thr Thr Val Leu Val Ser 
                405                 410                 415     


Asp Val Asn Asp Asn Ala Pro Thr Phe Thr Gln Thr Ser Tyr Thr Leu 
            420                 425                 430         


Phe Val Arg Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser 
        435                 440                 445             


Ala Thr Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Asn Tyr Ser Leu 
    450                 455                 460                 


Leu Pro Pro Gln Asp Leu His Leu Pro Leu Ala Ser Leu Val Ser Ile 
465                 470                 475                 480 


Asn Thr Asp Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu 
                485                 490                 495     


Ala Leu Gln Ala Phe Asp Phe Arg Val Gly Ala Thr Asp Arg Gly Ser 
            500                 505                 510         


Pro Ala Leu Ser Ser Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala 
        515                 520                 525             


Asn Asp Asn Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala 
    530                 535                 540                 


Pro Cys Thr Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp 
            580                 585                 590         


Ala His Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp 
        595                 600                 605             


Ala Ala Lys His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro 
    610                 615                 620                 


Pro Arg Ser Ala Thr Ala Thr Leu Gln Val Leu Leu Val Asp Gly Phe 
625                 630                 635                 640 


Ser Gln Pro Tyr Leu Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln 
                645                 650                 655     


Ala Asp Ser Leu Thr Val Tyr Leu 
            660                 


<210>  1053
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  1053

Glu Pro Arg Ser Tyr Ser Val Val Glu Glu Thr Glu Gly Ser Ser Phe 
1               5                   10                  15      


Val Thr Asn Leu Ala Lys Asp Leu Gly Leu Glu Gln Arg Glu Phe Ser 
            20                  25                  30          


Arg Arg Gly Val Arg Val Val Ser Arg Gly Asn Lys Leu His Leu Gln 
        35                  40                  45              


Leu Asn Gln Glu Thr Ala Asp Leu Leu Leu Asn Glu Lys Leu Asp Arg 
    50                  55                  60                  


Glu Asp Leu Cys Gly His Thr Glu Pro Cys Val Leu Arg Phe Gln Val 
65                  70                  75                  80  


Leu Leu Glu Ser Pro Phe Glu Phe Phe Gln Ala Glu Leu Gln Val Ile 
                85                  90                  95      


Asp Ile Asn Asp His Ser Pro Val Phe Leu Asp Lys Gln Met Leu Val 
            100                 105                 110         


Lys Val Ser Glu Ser Ser Pro Pro Gly Thr Thr Phe Pro Leu Lys Asn 
        115                 120                 125             


Ala Glu Asp Leu Asp Val Gly Gln Asn Asn Ile Glu Asn Tyr Ile Ile 
    130                 135                 140                 


Ser Pro Asn Ser Tyr Phe Arg Val Leu Thr Arg Lys Arg Ser Asp Gly 
145                 150                 155                 160 


Arg Lys Tyr Pro Glu Leu Val Leu Asp Lys Ala Leu Asp Arg Glu Glu 
                165                 170                 175     


Glu Ala Glu Leu Arg Leu Thr Leu Thr Ala Leu Asp Gly Gly Ser Pro 
            180                 185                 190         


Pro Arg Ser Gly Thr Ala Gln Val Tyr Ile Glu Val Leu Asp Val Asn 
        195                 200                 205             


Asp Asn Ala Pro Glu Phe Glu Gln Pro Phe Tyr Arg Val Gln Ile Ser 
    210                 215                 220                 


Glu Asp Ser Pro Val Gly Phe Leu Val Val Lys Val Ser Ala Thr Asp 
225                 230                 235                 240 


Val Asp Thr Gly Val Asn Gly Glu Ile Ser Tyr Ser Leu Phe Gln Ala 
                245                 250                 255     


Ser Glu Glu Ile Gly Lys Thr Phe Lys Ile Asn Pro Leu Thr Gly Glu 
            260                 265                 270         


Ile Glu Leu Lys Lys Gln Leu Asp Phe Glu Lys Leu Gln Ser Tyr Glu 
        275                 280                 285             


Val Asn Ile Glu Ala Arg Asp Ala Gly Thr Phe Ser Gly Lys Cys Thr 
    290                 295                 300                 


Val Leu Ile Gln Val Ile Asp Val Asn Asp His Ala Pro Glu Val Thr 
305                 310                 315                 320 


Met Ser Ala Phe Thr Ser Pro Ile Pro Glu Asn Ala Pro Glu Thr Val 
                325                 330                 335     


Val Ala Leu Phe Ser Val Ser Asp Leu Asp Ser Gly Glu Asn Gly Lys 
            340                 345                 350         


Ile Ser Cys Ser Ile Gln Glu Asp Leu Pro Phe Leu Leu Lys Ser Ala 
        355                 360                 365             


Glu Asn Phe Tyr Thr Leu Leu Thr Glu Arg Pro Leu Asp Arg Glu Ser 
    370                 375                 380                 


Arg Ala Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu Gly Thr Pro 
385                 390                 395                 400 


Met Leu Ile Thr Gln Leu Asn Met Thr Val Leu Ile Ala Asp Val Asn 
                405                 410                 415     


Asp Asn Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg 
            420                 425                 430         


Glu Asn Asn Ser Pro Ala Leu His Ile Arg Ser Val Ser Ala Thr Asp 
        435                 440                 445             


Arg Asp Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro Pro 
    450                 455                 460                 


Gln Asp Pro His Leu Pro Leu Thr Ser Leu Val Ser Ile Asn Ala Asp 
465                 470                 475                 480 


Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu Gln 
                485                 490                 495     


Gly Phe Gln Phe Arg Val Gly Ala Ser Asp His Gly Ser Pro Ala Leu 
            500                 505                 510         


Ser Ser Glu Ala Leu Val Arg Val Val Val Leu Asp Ala Asn Asp Asn 
        515                 520                 525             


Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr 
    530                 535                 540                 


Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val 
545                 550                 555                 560 


Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln 
                565                 570                 575     


Leu Leu Lys Ala Thr Glu Leu Gly Leu Phe Gly Val Trp Ala His Asn 
            580                 585                 590         


Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala Lys 
        595                 600                 605             


His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser 
    610                 615                 620                 


Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe Ser Gln Pro 
625                 630                 635                 640 


Tyr Leu Pro Leu Pro Glu Ala Ala Pro Thr Gln Ala Gln Ala Asp Leu 
                645                 650                 655     


Leu Thr Val Tyr Leu 
            660     


<210>  1054
<211>  664
<212>  PRT
<213>  Homo Sapiens

<400>  1054

Gly Trp Glu Pro Arg Arg Tyr Ser Val Met Glu Glu Thr Glu Arg Gly 
1               5                   10                  15      


Ser Phe Val Ala Asn Leu Ala Asn Asp Leu Gly Leu Gly Val Gly Glu 
            20                  25                  30          


Leu Ala Glu Arg Gly Ala Arg Val Val Ser Glu Asp Asn Glu Gln Gly 
        35                  40                  45              


Leu Gln Leu Asp Leu Gln Thr Gly Gln Leu Ile Leu Asn Glu Lys Leu 
    50                  55                  60                  


Asp Arg Glu Lys Leu Cys Gly Pro Thr Glu Pro Cys Ile Met His Phe 
65                  70                  75                  80  


Gln Val Leu Leu Lys Lys Pro Leu Glu Val Phe Arg Ala Glu Leu Leu 
                85                  90                  95      


Val Thr Asp Ile Asn Asp His Ser Pro Glu Phe Pro Glu Arg Glu Met 
            100                 105                 110         


Thr Leu Lys Ile Pro Glu Thr Ser Ser Leu Gly Thr Val Phe Pro Leu 
        115                 120                 125             


Lys Lys Ala Arg Asp Leu Asp Val Gly Ser Asn Asn Val Gln Asn Tyr 
    130                 135                 140                 


Asn Ile Ser Pro Asn Ser His Phe His Val Ser Thr Arg Thr Arg Gly 
145                 150                 155                 160 


Asp Gly Arg Lys Tyr Pro Glu Leu Val Leu Asp Thr Glu Leu Asp Arg 
                165                 170                 175     


Glu Glu Gln Ala Glu Leu Arg Leu Thr Leu Thr Ala Val Asp Gly Gly 
            180                 185                 190         


Ser Pro Pro Arg Ser Gly Thr Val Gln Ile Leu Ile Leu Val Leu Asp 
        195                 200                 205             


Ala Asn Asp Asn Ala Pro Glu Phe Val Gln Ala Leu Tyr Glu Val Gln 
    210                 215                 220                 


Val Pro Glu Asn Ser Pro Val Gly Ser Leu Val Val Lys Val Ser Ala 
225                 230                 235                 240 


Arg Asp Leu Asp Thr Gly Thr Asn Gly Glu Ile Ser Tyr Ser Leu Tyr 
                245                 250                 255     


Tyr Ser Ser Gln Glu Ile Asp Lys Pro Phe Glu Leu Ser Ser Leu Ser 
            260                 265                 270         


Gly Glu Ile Arg Leu Ile Lys Lys Leu Asp Phe Glu Thr Met Ser Ser 
        275                 280                 285             


Tyr Asp Leu Asp Ile Glu Ala Ser Asp Gly Gly Gly Leu Ser Gly Lys 
    290                 295                 300                 


Cys Ser Val Ser Val Lys Val Leu Asp Val Asn Asp Asn Phe Pro Glu 
305                 310                 315                 320 


Leu Ser Ile Ser Ser Leu Thr Ser Pro Ile Pro Glu Asn Ser Pro Glu 
                325                 330                 335     


Thr Glu Val Ala Leu Phe Arg Ile Arg Asp Arg Asp Ser Gly Glu Asn 
            340                 345                 350         


Gly Lys Met Ile Cys Ser Ile Gln Asp Asp Val Pro Phe Lys Leu Lys 
        355                 360                 365             


Pro Ser Val Glu Asn Phe Tyr Arg Leu Val Thr Glu Gly Ala Leu Asp 
    370                 375                 380                 


Arg Glu Thr Arg Ala Glu Tyr Asn Ile Thr Ile Thr Ile Thr Asp Leu 
385                 390                 395                 400 


Gly Thr Pro Arg Leu Lys Thr Glu Gln Ser Ile Thr Val Leu Val Ser 
                405                 410                 415     


Asp Val Asn Asp Asn Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu 
            420                 425                 430         


Phe Val Arg Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Arg 
        435                 440                 445             


Ala Thr Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu 
    450                 455                 460                 


Leu Pro Pro Gln Asp Pro His Leu Pro Leu Thr Ser Leu Val Ser Ile 
465                 470                 475                 480 


Asn Thr Asp Asn Gly His Leu Phe Ala Leu Gln Ser Leu Asp Tyr Glu 
                485                 490                 495     


Ala Leu Gln Ala Phe Glu Phe Arg Val Gly Ala Thr Asp Arg Gly Phe 
            500                 505                 510         


Pro Ala Leu Ser Ser Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala 
        515                 520                 525             


Asn Asp Asn Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala 
    530                 535                 540                 


Pro Cys Thr Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp 
            580                 585                 590         


Ala His Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp 
        595                 600                 605             


Val Ala Lys His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro 
    610                 615                 620                 


Pro Arg Ser Ala Thr Ala Thr Leu Gln Val Leu Leu Val Asp Gly Phe 
625                 630                 635                 640 


Ser Gln Pro Tyr Leu Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln 
                645                 650                 655     


Ala Asp Ser Leu Thr Val Tyr Leu 
            660                 


<210>  1055
<211>  662
<212>  PRT
<213>  Homo Sapiens

<400>  1055

Glu Leu Gly Ser Tyr Ser Val Val Glu Glu Thr Glu Arg Gly Ser Phe 
1               5                   10                  15      


Val Ala Asn Leu Gly Lys Asp Leu Gly Leu Gly Leu Thr Glu Met Ser 
            20                  25                  30          


Thr Arg Lys Ala Arg Ile Ile Ser Gln Gly Asn Lys Gln His Leu Gln 
        35                  40                  45              


Leu Lys Ala Gln Thr Gly Asp Leu Leu Ile Asn Glu Lys Leu Asp Arg 
    50                  55                  60                  


Glu Glu Leu Cys Gly Pro Thr Glu Pro Cys Ile Leu His Phe Gln Val 
65                  70                  75                  80  


Leu Met Glu Asn Pro Leu Glu Ile Phe Gln Ala Glu Leu Arg Val Ile 
                85                  90                  95      


Asp Ile Asn Asp His Ser Pro Met Phe Thr Glu Lys Glu Met Ile Leu 
            100                 105                 110         


Lys Ile Pro Glu Asn Ser Pro Leu Gly Thr Glu Phe Pro Leu Asn His 
        115                 120                 125             


Ala Leu Asp Leu Asp Val Gly Ser Asn Asn Val Gln Asn Tyr Lys Ile 
    130                 135                 140                 


Ser Pro Ser Ser His Phe Arg Val Leu Ile His Glu Phe Arg Asp Gly 
145                 150                 155                 160 


Arg Lys Tyr Pro Glu Leu Val Leu Asp Lys Glu Leu Asp Arg Glu Glu 
                165                 170                 175     


Glu Pro Gln Leu Arg Leu Thr Leu Thr Ala Leu Asp Gly Gly Ser Pro 
            180                 185                 190         


Pro Arg Ser Gly Thr Ala Gln Val Arg Ile Glu Val Val Asp Ile Asn 
        195                 200                 205             


Asp Asn Ala Pro Glu Phe Glu Gln Pro Ile Tyr Lys Val Gln Ile Pro 
    210                 215                 220                 


Glu Asn Ser Pro Leu Gly Ser Leu Val Ala Thr Val Ser Ala Arg Asp 
225                 230                 235                 240 


Leu Asp Gly Gly Ala Asn Gly Lys Ile Ser Tyr Thr Leu Phe Gln Pro 
                245                 250                 255     


Ser Glu Asp Ile Ser Lys Thr Leu Glu Val Asn Pro Met Thr Gly Glu 
            260                 265                 270         


Val Arg Leu Arg Lys Gln Val Asp Phe Glu Met Val Thr Ser Tyr Glu 
        275                 280                 285             


Val Arg Ile Lys Ala Thr Asp Gly Gly Gly Leu Ser Gly Lys Cys Thr 
    290                 295                 300                 


Leu Leu Leu Gln Val Val Asp Val Asn Asp Asn Pro Pro Gln Val Thr 
305                 310                 315                 320 


Met Ser Ala Leu Thr Ser Pro Ile Ala Glu Asn Ser Pro Glu Ile Val 
                325                 330                 335     


Val Ala Val Phe Ser Val Ser Asp Pro Asp Ser Gly Asn Asn Gly Lys 
            340                 345                 350         


Thr Ile Ser Ser Ile Gln Glu Asp Leu Pro Phe Leu Leu Lys Pro Ser 
        355                 360                 365             


Val Lys Asn Phe Tyr Thr Leu Val Thr Glu Arg Ala Leu Asp Arg Glu 
    370                 375                 380                 


Ala Arg Ala Glu Tyr Asn Ile Thr Leu Thr Val Thr Asp Met Gly Thr 
385                 390                 395                 400 


Pro Arg Leu Lys Thr Glu His Asn Ile Thr Val Gln Ile Ser Asp Val 
                405                 410                 415     


Asn Asp Asn Ala Pro Thr Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val 
            420                 425                 430         


Arg Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr 
        435                 440                 445             


Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro 
    450                 455                 460                 


Pro Gln Asp Pro His Leu Pro Leu Ala Ser Leu Val Ser Ile Asn Ala 
465                 470                 475                 480 


Asp Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu 
                485                 490                 495     


Gln Ala Phe Glu Phe Arg Val Gly Ala Thr Asp Arg Gly Ser Pro Ala 
            500                 505                 510         


Leu Ser Arg Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala Asn Asp 
        515                 520                 525             


Asn Ser Pro Leu Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys 
    530                 535                 540                 


Thr Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys 
545                 550                 555                 560 


Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr 
                565                 570                 575     


Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp Ala His 
            580                 585                 590         


Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala 
        595                 600                 605             


Lys Gln Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg 
    610                 615                 620                 


Ser Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe Ser Gln 
625                 630                 635                 640 


Pro Phe Leu Pro Leu Pro Glu Ala Ala Pro Gly Gln Thr Gln Ala Asn 
                645                 650                 655     


Ser Leu Thr Val Tyr Leu 
            660         


<210>  1056
<211>  664
<212>  PRT
<213>  Homo Sapiens

<400>  1056

Gly Ser Glu Ser Arg Arg Tyr Ser Val Ala Glu Glu Lys Glu Arg Gly 
1               5                   10                  15      


Phe Leu Ile Ala Asn Leu Ala Lys Asp Leu Gly Leu Arg Val Glu Glu 
            20                  25                  30          


Leu Ala Ala Arg Gly Ala Gln Val Val Ser Lys Gly Asn Lys Gln His 
        35                  40                  45              


Phe Gln Leu Ser His Gln Thr Gly Asp Leu Leu Leu Asn Glu Lys Leu 
    50                  55                  60                  


Asp Arg Glu Glu Leu Cys Gly Pro Thr Glu Pro Cys Ile Leu His Phe 
65                  70                  75                  80  


Gln Ile Leu Leu Gln Asn Pro Leu Gln Phe Val Thr Asn Glu Leu Arg 
                85                  90                  95      


Ile Ile Asp Val Asn Asp His Ser Pro Val Phe Phe Glu Asn Glu Met 
            100                 105                 110         


His Leu Lys Ile Leu Glu Ser Thr Leu Pro Gly Thr Val Ile Pro Leu 
        115                 120                 125             


Gly Asn Ala Glu Asp Leu Asp Val Gly Arg Asn Ser Leu Gln Asn Tyr 
    130                 135                 140                 


Thr Ile Thr Pro Asn Ser His Phe His Val Leu Thr Arg Ser Arg Arg 
145                 150                 155                 160 


Asp Gly Arg Lys Tyr Pro Glu Leu Val Leu Asp Lys Ala Leu Asp Arg 
                165                 170                 175     


Glu Glu Gln Pro Glu Leu Ser Leu Thr Leu Thr Ala Leu Asp Gly Gly 
            180                 185                 190         


Ser Pro Pro Arg Ser Gly Thr Ala Gln Ile Asn Ile Gln Val Leu Asp 
        195                 200                 205             


Ile Asn Asp Asn Ala Pro Glu Phe Ala Gln Pro Leu Tyr Glu Val Ala 
    210                 215                 220                 


Val Leu Glu Asn Thr Pro Val Asn Ser Val Ile Val Thr Val Ser Ala 
225                 230                 235                 240 


Ser Asp Leu Asp Thr Gly Ser Phe Gly Thr Ile Ser Tyr Ala Phe Phe 
                245                 250                 255     


His Ala Ser Glu Glu Ile Arg Lys Thr Phe Gln Leu Asn Pro Ile Thr 
            260                 265                 270         


Gly Asp Met Gln Leu Val Lys Tyr Leu Asn Phe Glu Ala Ile Asn Ser 
        275                 280                 285             


Tyr Glu Val Asp Ile Glu Ala Lys Asp Gly Gly Gly Leu Ser Gly Lys 
    290                 295                 300                 


Ser Thr Val Ile Val Gln Val Val Asp Val Asn Asp Asn Pro Pro Glu 
305                 310                 315                 320 


Leu Thr Leu Ser Ser Val Asn Ser Pro Ile Pro Glu Asn Ser Gly Glu 
                325                 330                 335     


Thr Val Leu Ala Val Phe Ser Val Ser Asp Leu Asp Ser Gly Asp Asn 
            340                 345                 350         


Gly Arg Val Met Cys Ser Ile Glu Asn Asn Leu Pro Phe Phe Leu Lys 
        355                 360                 365             


Pro Ser Val Glu Asn Phe Tyr Thr Leu Val Ser Glu Gly Ala Leu Asp 
    370                 375                 380                 


Arg Glu Thr Arg Ser Glu Tyr Asn Ile Thr Ile Thr Ile Thr Asp Leu 
385                 390                 395                 400 


Gly Thr Pro Arg Leu Lys Thr Lys Tyr Asn Ile Thr Val Leu Val Ser 
                405                 410                 415     


Asp Val Asn Asp Asn Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu 
            420                 425                 430         


Phe Val Arg Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser 
        435                 440                 445             


Ala Thr Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu 
    450                 455                 460                 


Leu Pro Pro Gln Asp Pro His Leu Pro Leu Ser Ser Leu Val Ser Ile 
465                 470                 475                 480 


Asn Ala Asp Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu 
                485                 490                 495     


Ala Leu Gln Ala Phe Glu Phe Arg Val Gly Ala Ala Asp Arg Gly Ser 
            500                 505                 510         


Pro Ala Leu Ser Ser Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala 
        515                 520                 525             


Asn Asp Asn Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala 
    530                 535                 540                 


Pro Cys Thr Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Ser Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp 
            580                 585                 590         


Ala His Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp 
        595                 600                 605             


Ala Ala Lys His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro 
    610                 615                 620                 


Pro Arg Ser Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe 
625                 630                 635                 640 


Ser Gln Pro Tyr Leu Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln 
                645                 650                 655     


Ala Asp Leu Leu Thr Val Tyr Leu 
            660                 


<210>  1057
<211>  659
<212>  PRT
<213>  Homo Sapiens

<400>  1057

Val Arg Tyr Ser Ile Pro Glu Glu Thr Glu Ser Gly Tyr Ser Val Ala 
1               5                   10                  15      


Asn Leu Ala Lys Asp Leu Gly Leu Gly Val Gly Glu Leu Ala Thr Arg 
            20                  25                  30          


Gly Ala Arg Met His Tyr Lys Gly Asn Lys Glu Leu Leu Gln Leu Asp 
        35                  40                  45              


Ile Lys Thr Gly Asn Leu Leu Leu Tyr Glu Lys Leu Asp Arg Glu Val 
    50                  55                  60                  


Met Cys Gly Ala Thr Glu Pro Cys Ile Leu His Phe Gln Leu Leu Leu 
65                  70                  75                  80  


Glu Asn Pro Val Gln Phe Phe Gln Thr Asp Leu Gln Leu Thr Asp Ile 
                85                  90                  95      


Asn Asp His Ala Pro Glu Phe Pro Glu Lys Glu Met Leu Leu Lys Ile 
            100                 105                 110         


Pro Glu Ser Thr Gln Pro Gly Thr Val Phe Pro Leu Lys Ile Ala Gln 
        115                 120                 125             


Asp Phe Asp Ile Gly Ser Asn Thr Val Gln Asn Tyr Thr Ile Ser Pro 
    130                 135                 140                 


Asn Ser His Phe His Val Ala Thr His Asn Arg Gly Asp Gly Arg Lys 
145                 150                 155                 160 


Tyr Pro Glu Leu Val Leu Asp Lys Ala Leu Asp Arg Glu Glu Arg Pro 
                165                 170                 175     


Glu Leu Ser Leu Thr Leu Thr Ala Leu Asp Gly Gly Ala Pro Pro Arg 
            180                 185                 190         


Ser Gly Thr Thr Thr Ile Arg Ile Val Val Leu Asp Asn Asn Asp Asn 
        195                 200                 205             


Ala Pro Glu Phe Leu Gln Ser Phe Tyr Glu Val Gln Val Pro Glu Asn 
    210                 215                 220                 


Ser Pro Leu Asn Ser Leu Val Val Val Val Ser Ala Arg Asp Leu Asp 
225                 230                 235                 240 


Ala Gly Ala Tyr Gly Ser Val Ala Tyr Ala Leu Phe Gln Gly Asp Glu 
                245                 250                 255     


Val Thr Gln Pro Phe Val Ile Asp Glu Lys Thr Ala Glu Ile Arg Leu 
            260                 265                 270         


Lys Arg Ala Leu Asp Phe Glu Ala Thr Pro Tyr Tyr Asn Val Glu Ile 
        275                 280                 285             


Val Ala Thr Asp Gly Gly Gly Leu Ser Gly Lys Cys Thr Val Ala Ile 
    290                 295                 300                 


Glu Val Val Asp Val Asn Asp Asn Ala Pro Glu Leu Thr Met Ser Thr 
305                 310                 315                 320 


Leu Ser Ser Pro Thr Pro Glu Asn Ala Pro Glu Thr Val Val Ala Val 
                325                 330                 335     


Phe Ser Val Ser Asp Pro Asp Ser Gly Asp Asn Gly Arg Met Ile Cys 
            340                 345                 350         


Ser Ile Gln Asn Asp Leu Pro Phe Leu Leu Lys Pro Thr Leu Lys Asn 
        355                 360                 365             


Phe Tyr Thr Leu Val Thr Gln Arg Thr Leu Asp Arg Glu Ser Gln Ala 
    370                 375                 380                 


Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Met Gly Thr Pro Arg Leu 
385                 390                 395                 400 


Lys Thr Glu His Asn Ile Thr Val Leu Val Ser Asp Val Asn Asp Asn 
                405                 410                 415     


Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg Glu Asn 
            420                 425                 430         


Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr Asp Arg Asp 
        435                 440                 445             


Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro Pro Gln Asn 
    450                 455                 460                 


Pro His Leu Arg Leu Ala Ser Leu Val Ser Ile Asn Ala Asp Asn Gly 
465                 470                 475                 480 


His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu Gln Ala Phe 
                485                 490                 495     


Glu Phe Arg Val Gly Ala Thr Asp Arg Gly Ser Pro Ala Leu Ser Ser 
            500                 505                 510         


Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala Asn Asp Asn Ser Pro 
        515                 520                 525             


Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr Glu Leu 
    530                 535                 540                 


Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val Val Ala 
545                 550                 555                 560 


Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln Leu Leu 
                565                 570                 575     


Lys Ala Thr Glu Pro Gly Leu Phe Ser Met Trp Ala His Asn Gly Glu 
            580                 585                 590         


Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala Lys His Arg 
        595                 600                 605             


Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser Ala Thr 
    610                 615                 620                 


Ala Thr Leu His Val Leu Leu Val Asp Gly Phe Ser Gln Pro Tyr Leu 
625                 630                 635                 640 


Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln Ala Asp Ser Leu Thr 
                645                 650                 655     


Val Tyr Leu 
            


<210>  1058
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  1058

Glu Ser Ile Gln Tyr Ser Val Leu Glu Glu Thr Glu Ser Gly Thr Phe 
1               5                   10                  15      


Val Ala Asn Leu Thr Lys Asp Leu Gly Leu Arg Val Gly Glu Leu Ala 
            20                  25                  30          


Ser Arg Gly Ala Arg Val Val Phe Lys Gly Asn Arg Gln His Leu Gln 
        35                  40                  45              


Phe Asp Pro Gln Thr His Asp Leu Leu Leu Asn Glu Lys Leu Asp Arg 
    50                  55                  60                  


Glu Glu Leu Cys Gly Ser Thr Glu Pro Cys Val Leu Pro Phe Gln Val 
65                  70                  75                  80  


Leu Leu Glu Asn Pro Leu Gln Phe Phe Gln Ala Ser Leu Arg Val Arg 
                85                  90                  95      


Asp Ile Asn Asp His Ala Pro Glu Phe Pro Ala Arg Glu Met Leu Leu 
            100                 105                 110         


Lys Ile Ser Glu Ile Thr Met Pro Gly Lys Ile Phe Pro Leu Lys Met 
        115                 120                 125             


Ala His Asp Leu Asp Thr Gly Ser Asn Gly Leu Gln Arg Tyr Thr Ile 
    130                 135                 140                 


Ser Ser Asn Pro His Phe His Val Leu Thr Arg Asn Arg Ser Glu Gly 
145                 150                 155                 160 


Arg Lys Phe Pro Glu Leu Val Leu Asp Lys Pro Leu Asp Arg Glu Glu 
                165                 170                 175     


Gln Pro Gln Leu Arg Leu Thr Leu Ile Ala Leu Asp Gly Gly Ser Pro 
            180                 185                 190         


Pro Arg Ser Gly Thr Ser Glu Ile Gln Ile Gln Val Leu Asp Ile Asn 
        195                 200                 205             


Asp Asn Val Pro Glu Phe Ala Gln Glu Leu Tyr Glu Ala Gln Val Pro 
    210                 215                 220                 


Glu Asn Asn Pro Leu Gly Ser Leu Val Ile Thr Val Ser Ala Arg Asp 
225                 230                 235                 240 


Leu Asp Ala Gly Ser Phe Gly Lys Val Ser Tyr Ala Leu Phe Gln Val 
                245                 250                 255     


Asp Asp Val Asn Gln Pro Phe Glu Ile Asn Ala Ile Thr Gly Glu Ile 
            260                 265                 270         


Arg Leu Arg Lys Ala Leu Asp Phe Glu Glu Ile Gln Ser Tyr Asp Val 
        275                 280                 285             


Asp Val Glu Ala Thr Asp Gly Gly Gly Leu Ser Gly Lys Cys Ser Leu 
    290                 295                 300                 


Val Val Arg Val Leu Asp Val Asn Asp Asn Ala Pro Glu Leu Thr Met 
305                 310                 315                 320 


Ser Phe Phe Ile Ser Leu Ile Pro Glu Asn Leu Pro Glu Ile Thr Val 
                325                 330                 335     


Ala Val Phe Ser Val Ser Asp Ala Asp Ser Gly His Asn Gln Gln Val 
            340                 345                 350         


Ile Cys Ser Ile Glu Asn Asn Leu Pro Phe Leu Leu Arg Pro Ser Val 
        355                 360                 365             


Glu Asn Phe Tyr Thr Leu Val Thr Glu Gly Ala Leu Asp Arg Glu Ser 
    370                 375                 380                 


Arg Ala Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu Gly Thr Pro 
385                 390                 395                 400 


Arg Leu Lys Thr Gln Gln Ser Ile Thr Val Gln Val Ser Asp Val Asn 
                405                 410                 415     


Asp Asn Val Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu Phe Val Arg 
            420                 425                 430         


Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser Ala Thr Asp 
        435                 440                 445             


Arg Asp Ser Gly Ile Asn Ala Gln Val Thr Tyr Ser Leu Leu Pro Pro 
    450                 455                 460                 


Gln Asp Pro His Leu Pro Leu Ser Ser Leu Val Ser Ile Asn Ala Asp 
465                 470                 475                 480 


Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu Ala Leu Gln 
                485                 490                 495     


Ser Phe Glu Phe Arg Val Gly Ala Thr Asp Arg Gly Ser Pro Ala Leu 
            500                 505                 510         


Ser Ser Glu Ala Leu Val Arg Leu Leu Val Leu Asp Ala Asn Asp Asn 
        515                 520                 525             


Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala Pro Cys Thr 
    530                 535                 540                 


Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val Thr Lys Val 
545                 550                 555                 560 


Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu Ser Tyr Gln 
                565                 570                 575     


Leu Leu Lys Ala Thr Glu Leu Gly Leu Phe Gly Val Trp Ala His Asn 
            580                 585                 590         


Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp Ala Ala Lys 
        595                 600                 605             


His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro Pro Arg Ser 
    610                 615                 620                 


Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe Ser Gln Pro 
625                 630                 635                 640 


Tyr Leu Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln Ala Asp Ser 
                645                 650                 655     


Leu Thr Val Tyr Leu 
            660     


<210>  1059
<211>  662
<212>  PRT
<213>  Homo Sapiens

<400>  1059

Gly Ala Glu Pro Leu Arg Tyr Phe Val Ala Glu Glu Thr Glu Arg Gly 
1               5                   10                  15      


Thr Phe Leu Thr Asn Leu Ala Lys Asp Leu Gly Leu Gly Val Gly Glu 
            20                  25                  30          


Leu Arg Ala Arg Gly Thr Arg Ile Val Ser Asp Gln Asn Met Gln Ile 
        35                  40                  45              


Leu Leu Leu Ser Ser Leu Thr Gly Asp Leu Leu Leu Asn Glu Lys Leu 
    50                  55                  60                  


Asp Arg Glu Glu Leu Cys Gly Pro Arg Glu Pro Cys Val Leu Pro Phe 
65                  70                  75                  80  


Gln Leu Leu Leu Glu Lys Pro Phe Gln Ile Phe Arg Ala Glu Leu Trp 
                85                  90                  95      


Val Arg Asp Ile Asn Asp His Ala Pro Val Phe Leu Asp Arg Glu Ile 
            100                 105                 110         


Ser Leu Lys Ile Leu Glu Ser Thr Thr Pro Gly Ala Ala Phe Leu Leu 
        115                 120                 125             


Glu Ser Ala Gln Asp Ser Asp Val Gly Thr Asn Ser Leu Ser Asn Tyr 
    130                 135                 140                 


Thr Ile Ser Pro Asn Ala Tyr Phe His Ile Asn Val His Asp Ser Gly 
145                 150                 155                 160 


Glu Gly Asn Ile Tyr Pro Glu Leu Val Leu Asn Gln Val Leu Asp Arg 
                165                 170                 175     


Glu Glu Ile Pro Glu Phe Ser Leu Thr Leu Thr Ala Leu Asp Gly Gly 
            180                 185                 190         


Ser Pro Pro Arg Ser Gly Thr Ala Leu Val Arg Ile Leu Val Leu Asp 
        195                 200                 205             


Val Asn Asp Asn Ala Pro Asp Phe Val Arg Ser Leu Tyr Lys Val Gln 
    210                 215                 220                 


Val Pro Glu Asn Ser Pro Val Gly Ser Met Val Val Ser Val Ser Ala 
225                 230                 235                 240 


Arg Asp Leu Asp Thr Gly Ser Asn Gly Glu Ile Ala Tyr Ala Phe Ser 
                245                 250                 255     


Tyr Ala Thr Glu Arg Ile Leu Lys Thr Phe Gln Ile Asn Pro Thr Ser 
            260                 265                 270         


Gly Ser Leu His Leu Lys Ala Gln Leu Asp Tyr Glu Ala Ile Gln Thr 
        275                 280                 285             


Tyr Thr Leu Thr Ile Gln Ala Lys Asp Gly Gly Gly Leu Ser Gly Lys 
    290                 295                 300                 


Cys Thr Val Val Val Asp Val Thr Asp Ile Asn Asp Asn Arg Pro Glu 
305                 310                 315                 320 


Leu Leu Leu Ser Ser Leu Thr Ser Pro Ile Ala Glu Asn Ser Pro Glu 
                325                 330                 335     


Thr Val Val Ala Val Phe Arg Ile Arg Asp Arg Asp Ser Gly Asn Asn 
            340                 345                 350         


Gly Lys Thr Val Cys Ser Ile Gln Asp Asp Leu Pro Phe Ile Leu Lys 
        355                 360                 365             


Pro Ser Val Glu Asn Phe Tyr Thr Leu Val Thr Glu Lys Pro Leu Asp 
    370                 375                 380                 


Arg Glu Arg Asn Thr Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu 
385                 390                 395                 400 


Gly Thr Pro Arg Leu Lys Thr Glu His Asn Ile Thr Val Leu Val Ser 
                405                 410                 415     


Asp Val Asn Asp Asn Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu 
            420                 425                 430         


Phe Val Arg Glu Asn Asn Ser Pro Ala Leu Pro Ile Gly Ser Val Ser 
        435                 440                 445             


Ala Thr Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Ile Tyr Ser Leu 
    450                 455                 460                 


Leu Pro Ser Gln Asp Pro His Leu Pro Leu Ala Ser Leu Val Ser Ile 
465                 470                 475                 480 


Asn Ala Asp Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu 
                485                 490                 495     


Ala Leu Gln Ala Phe Glu Phe Arg Val Gly Ala Thr Asp Arg Gly Ser 
            500                 505                 510         


Pro Ala Leu Ser Ser Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala 
        515                 520                 525             


Asn Asp Asn Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Ser Ser Ala 
    530                 535                 540                 


Pro Cys Thr Glu Pro Leu Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp 
            580                 585                 590         


Ala His Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp 
        595                 600                 605             


Ala Ala Lys Gln Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro 
    610                 615                 620                 


Pro Arg Ser Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe 
625                 630                 635                 640 


Ser Gln Pro Tyr Leu Arg Leu Pro Glu Ala Ala Pro Asp Gln Ala Asn 
                645                 650                 655     


Ser Leu Thr Val Tyr Leu 
            660         


<210>  1060
<211>  664
<212>  PRT
<213>  Homo Sapiens

<400>  1060

Gly Ser Gly Phe Gly Arg Tyr Ser Val Thr Glu Glu Thr Glu Lys Gly 
1               5                   10                  15      


Ser Phe Val Val Asn Leu Ala Lys Asp Leu Gly Leu Ala Glu Gly Glu 
            20                  25                  30          


Leu Ala Ala Arg Gly Thr Arg Val Val Ser Asp Asp Asn Lys Gln Tyr 
        35                  40                  45              


Leu Leu Leu Asp Ser His Thr Gly Asn Leu Leu Thr Asn Glu Lys Leu 
    50                  55                  60                  


Asp Arg Glu Lys Leu Cys Gly Pro Lys Glu Pro Cys Met Leu Tyr Phe 
65                  70                  75                  80  


Gln Ile Leu Met Asp Asp Pro Phe Gln Ile Tyr Arg Ala Glu Leu Arg 
                85                  90                  95      


Val Arg Asp Ile Asn Asp His Ser Pro Val Phe Arg His Lys Glu Met 
            100                 105                 110         


Val Leu Lys Ile Ser Glu Asn Thr Ala Glu Gly Thr Ala Phe Arg Leu 
        115                 120                 125             


Glu Arg Ala Gln Asp Pro Asp Glu Gly His Asn Ser Ile Gln Asn Tyr 
    130                 135                 140                 


Thr Ile Ser Ser Asn Ser Phe Phe His Ile Lys Ile Ser Gly Ser Asp 
145                 150                 155                 160 


Glu Gly Met Ile Tyr Pro Glu Leu Val Leu Asp Lys Ala Leu Asp Arg 
                165                 170                 175     


Glu Glu Gln Glu Glu Leu Ser Leu Thr Leu Thr Ala Leu Asp Gly Gly 
            180                 185                 190         


Ser Pro Ser Arg Ser Gly Thr Ser Thr Ile Arg Ile Val Val Leu Asp 
        195                 200                 205             


Val Asn Asp Asn Ala Pro Gln Phe Ala Gln Ala Leu Tyr Glu Thr Gln 
    210                 215                 220                 


Ala Pro Glu Asn Ser Pro Val Gly Ser Leu Ile Val Lys Val Ser Ala 
225                 230                 235                 240 


Gly Asp Ala Asp Ser Gly Val Asn Ala Glu Val Ser Tyr Ser Phe Phe 
                245                 250                 255     


Asp Ala Ser Glu Asp Ile Leu Thr Thr Phe Gln Ile Asn Pro Phe Ser 
            260                 265                 270         


Gly Glu Ile Phe Leu Arg Glu Leu Leu Asp Tyr Glu Leu Val Asn Ser 
        275                 280                 285             


Tyr Lys Ile Asn Ile Gln Ala Met Asp Gly Gly Gly Leu Ser Ala Arg 
    290                 295                 300                 


Cys Thr Val Leu Ile Lys Val Leu Asp Ser Asn Asp Asn Pro Pro Glu 
305                 310                 315                 320 


Leu Ile Ile Ser Ser Leu Ser Asn Ser Val Ala Glu Asn Ser Pro Gly 
                325                 330                 335     


Ile Val Leu Ala Val Phe Lys Ile Lys Asp Arg Asp Ser Gly Glu Asn 
            340                 345                 350         


Gly Lys Thr Ile Cys Tyr Val Gln Asp Asn Leu Pro Phe Phe Leu Lys 
        355                 360                 365             


Pro Ser Val Asp Asn Phe Tyr Ile Leu Met Thr Glu Gly Ala Leu Asp 
    370                 375                 380                 


Arg Glu Ser Lys Ala Glu Tyr Asn Ile Thr Ile Thr Val Thr Asp Leu 
385                 390                 395                 400 


Gly Thr Pro Arg Leu Lys Thr Glu His Ser Ile Thr Leu Gln Val Ser 
                405                 410                 415     


Asp Val Asn Asp Asn Ala Pro Ala Phe Thr Gln Thr Ser Tyr Thr Leu 
            420                 425                 430         


Phe Val Arg Glu Asn Asn Ser Pro Ala Leu His Ile Gly Ser Val Ser 
        435                 440                 445             


Ala Thr Asp Arg Asp Ser Gly Thr Asn Ala Gln Val Thr Tyr Ser Leu 
    450                 455                 460                 


Leu Pro Pro Gln Asp Pro His Leu Pro Leu Ala Ser Leu Val Ser Ile 
465                 470                 475                 480 


Asn Ala Asp Asn Gly His Leu Phe Ala Leu Arg Ser Leu Asp Tyr Glu 
                485                 490                 495     


Ala Leu Gln Ala Phe Asp Phe Arg Val Gly Ala Ser Asp Arg Gly Ser 
            500                 505                 510         


Pro Ala Leu Ser Ser Glu Ala Leu Val Arg Val Leu Val Leu Asp Ala 
        515                 520                 525             


Asn Asp Asn Ser Pro Phe Val Leu Tyr Pro Leu Gln Asn Gly Ser Ala 
    530                 535                 540                 


Pro Cys Thr Glu Leu Val Pro Arg Ala Ala Glu Pro Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Gly Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Gln Leu Leu Lys Ala Thr Glu Pro Gly Leu Phe Gly Val Trp 
            580                 585                 590         


Ala His Asn Gly Glu Val Arg Thr Ala Arg Leu Leu Ser Glu Arg Asp 
        595                 600                 605             


Ala Ala Lys His Arg Leu Val Val Leu Val Lys Asp Asn Gly Glu Pro 
    610                 615                 620                 


Pro Arg Ser Ala Thr Ala Thr Leu His Val Leu Leu Val Asp Gly Phe 
625                 630                 635                 640 


Ser Gln Pro Tyr Leu Pro Leu Pro Glu Ala Ala Pro Ala Gln Ala Gln 
                645                 650                 655     


Ala Asp Leu Leu Thr Val Tyr Leu 
            660                 


<210>  1061
<211>  664
<212>  PRT
<213>  Homo Sapiens

<400>  1061

Glu Gln Ile Leu Tyr Ser Val Phe Glu Glu Gln Glu Glu Gly Ser Val 
1               5                   10                  15      


Val Gly Asn Ile Ala Lys Asp Leu Gly Leu Ala Pro Arg Glu Leu Ala 
            20                  25                  30          


Glu Arg Gly Val Arg Ile Val Ser Arg Gly Arg Thr Gln Leu Phe Ala 
        35                  40                  45              


Leu Asn Pro Arg Ser Gly Thr Leu Val Thr Ala Gly Arg Ile Asp Arg 
    50                  55                  60                  


Glu Glu Leu Cys Asp Arg Ser Pro Asn Cys Val Thr Asn Leu Glu Ile 
65                  70                  75                  80  


Leu Leu Glu Asp Thr Val Lys Ile Leu Arg Val Glu Val Glu Ile Ile 
                85                  90                  95      


Asp Val Asn Asp Asn Pro Pro Ser Phe Gly Thr Glu Gln Arg Glu Ile 
            100                 105                 110         


Lys Val Ala Glu Asn Glu Asn Pro Gly Ala Arg Phe Pro Leu Pro Glu 
        115                 120                 125             


Ala Phe Asp Pro Asp Val Gly Val Asn Ser Leu Gln Gly Tyr Gln Leu 
    130                 135                 140                 


Asn Ser Asn Gly Tyr Phe Ser Leu Asp Val Gln Ser Gly Ala Asp Gly 
145                 150                 155                 160 


Ile Lys Tyr Pro Glu Leu Val Leu Glu Arg Ala Leu Asp Arg Glu Glu 
                165                 170                 175     


Glu Ala Val His His Leu Val Leu Thr Ala Phe Asp Gly Gly Asp Pro 
            180                 185                 190         


Val Arg Ser Gly Thr Ala Arg Ile Leu Ile Ile Leu Val Asp Thr Asn 
        195                 200                 205             


Asp Asn Ala Pro Val Phe Thr Gln Pro Glu Tyr His Val Ser Val Arg 
    210                 215                 220                 


Glu Asn Val Pro Val Gly Thr Arg Leu Leu Thr Val Lys Ala Thr Asp 
225                 230                 235                 240 


Pro Asp Glu Gly Ala Asn Gly Asp Val Thr Tyr Ser Phe Arg Lys Val 
                245                 250                 255     


Arg Asp Lys Ile Ser Gln Leu Phe Gln Leu Asn Ser Leu Ser Gly Asp 
            260                 265                 270         


Ile Thr Ile Leu Gly Gly Leu Asp Tyr Glu Asp Ser Gly Phe Tyr Asp 
        275                 280                 285             


Ile Asp Val Glu Ala His Asp Gly Pro Gly Leu Arg Ala Arg Ser Lys 
    290                 295                 300                 


Val Leu Val Thr Val Leu Asp Glu Asn Asp Asn Ala Pro Glu Val Thr 
305                 310                 315                 320 


Val Thr Ser Leu Thr Ser Ser Val Gln Glu Ser Ser Ser Pro Gly Thr 
                325                 330                 335     


Val Ile Ala Leu Phe Asn Val His Asp Ser Asp Ser Gly Gly Asn Gly 
            340                 345                 350         


Leu Val Thr Cys Ser Ile Pro Asp Asn Leu Pro Phe Thr Leu Glu Lys 
        355                 360                 365             


Thr Tyr Gly Asn Tyr Tyr Arg Leu Leu Thr His Arg Thr Leu Asp Arg 
    370                 375                 380                 


Glu Glu Val Ser Glu Tyr Asn Ile Thr Val Thr Ala Thr Asp Gln Gly 
385                 390                 395                 400 


Thr Pro Pro Leu Ser Thr Glu Thr His Ile Ser Leu Gln Val Met Asp 
                405                 410                 415     


Ile Asn Asp Asn Pro Pro Thr Phe Pro His Ala Ser Tyr Ser Ala Tyr 
            420                 425                 430         


Ile Pro Glu Asn Asn Pro Arg Gly Ala Ser Ile Leu Ser Met Thr Ala 
        435                 440                 445             


Gln Asp Pro Asp Ser Gly Asp Asn Ala Arg Ile Thr Tyr Ser Leu Ala 
    450                 455                 460                 


Glu Asp Thr Phe Gln Gly Ala Pro Leu Ser Ser Tyr Val Ser Ile Asn 
465                 470                 475                 480 


Ser Asn Thr Gly Ile Leu Tyr Ala Leu Cys Ser Phe Asp Tyr Glu Gln 
                485                 490                 495     


Phe Arg Asp Leu Gln Leu Leu Met Thr Ala Ser Asp Ser Gly Asp Pro 
            500                 505                 510         


Pro Leu Ser Ser Asn Val Ser Leu Ser Leu Phe Val Leu Asp Gln Asn 
        515                 520                 525             


Asp Asn Val Pro Glu Ile Leu Tyr Pro Thr Phe Pro Thr Asp Gly Ser 
    530                 535                 540                 


Thr Gly Val Glu Leu Ala Pro Arg Ser Ala Asp Ser Gly Tyr Leu Val 
545                 550                 555                 560 


Thr Lys Val Val Ala Val Asp Arg Asp Ser Gly Gln Asn Ala Trp Leu 
                565                 570                 575     


Ser Tyr Ser Leu Leu Lys Ser Ser Glu Pro Gly Leu Phe Ala Val Gly 
            580                 585                 590         


Leu His Thr Gly Glu Val Arg Thr Ala Arg Ala Leu Leu Asp Arg Asp 
        595                 600                 605             


Ala Leu Lys Gln Arg Leu Val Val Val Val Gln Asp His Gly Gln Pro 
    610                 615                 620                 


Pro Leu Ser Ala Thr Val Thr Leu Thr Val Ala Val Ala Asp Ser Ile 
625                 630                 635                 640 


Pro Asp Val Leu Ala Asp Leu Gly Ser Leu Lys Pro Ser Ala Asp Pro 
                645                 650                 655     


Asp Asp Ser Gly Leu Thr Leu Tyr 
            660                 


<210>  1062
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  1062

Glu Pro Ile Arg Tyr Ala Ile Pro Glu Glu Leu Asp Arg Gly Ser Leu 
1               5                   10                  15      


Val Gly Asn Leu Ala Lys Asp Leu Gly Phe Gly Val Gly Asp Leu Pro 
            20                  25                  30          


Thr Arg Asn Leu Arg Val Ile Ala Glu Lys Lys Phe Phe Thr Val Ser 
        35                  40                  45              


Pro Glu Asn Gly Asn Leu Leu Val Ser Asp Arg Ile Asp Arg Glu Glu 
    50                  55                  60                  


Ile Cys Gly Lys Lys Ser Thr Cys Val Leu Glu Phe Glu Met Val Ala 
65                  70                  75                  80  


Glu Lys Pro Leu Asn Phe Phe His Val Thr Val Leu Ile Gln Asp Ile 
                85                  90                  95      


Asn Asp Asn Pro Pro Thr Phe Ser Gln Asn Ile Thr Glu Leu Glu Ile 
            100                 105                 110         


Ser Glu Leu Ala Leu Thr Gly Ala Thr Phe Ala Leu Glu Ser Ala Gln 
        115                 120                 125             


Asp Pro Asp Val Gly Val Asn Ser Leu Gln Gln Tyr Tyr Leu Ser Pro 
    130                 135                 140                 


Asp Pro His Phe Ser Leu Ile Gln Lys Glu Asn Leu Asp Gly Ser Arg 
145                 150                 155                 160 


Tyr Pro Glu Leu Val Leu Lys Ala Pro Leu Asp Arg Glu Glu Gln Pro 
                165                 170                 175     


His His His Leu Val Leu Thr Ala Val Asp Gly Gly Glu Pro Ser Arg 
            180                 185                 190         


Ser Cys Thr Thr Gln Ile Arg Val Ile Val Ala Asp Ala Asn Asp Asn 
        195                 200                 205             


Pro Pro Val Phe Thr Gln Asp Met Tyr Arg Val Asn Val Ala Glu Asn 
    210                 215                 220                 


Leu Pro Ala Gly Ser Ser Val Leu Lys Val Met Ala Ile Asp Met Asp 
225                 230                 235                 240 


Glu Gly Ile Asn Ala Glu Ile Ile Tyr Ala Phe Ile Asn Ile Gly Lys 
                245                 250                 255     


Glu Val Arg Gln Leu Phe Lys Leu Asp Ser Lys Thr Gly Glu Leu Thr 
            260                 265                 270         


Thr Ile Gly Glu Leu Asp Phe Glu Glu Arg Asp Ser Tyr Thr Ile Gly 
        275                 280                 285             


Val Glu Ala Lys Asp Gly Gly His His Thr Ala Tyr Cys Lys Val Gln 
    290                 295                 300                 


Ile Asp Ile Ser Asp Glu Asn Asp Asn Ala Pro Glu Ile Thr Leu Ala 
305                 310                 315                 320 


Ser Glu Ser Gln His Ile Gln Glu Asp Ala Glu Leu Gly Thr Ala Val 
                325                 330                 335     


Ala Leu Ile Lys Thr His Asp Leu Asp Ser Gly Phe Asn Gly Glu Ile 
            340                 345                 350         


Leu Cys Gln Leu Lys Gly Asn Phe Pro Phe Lys Ile Val Gln Asp Thr 
        355                 360                 365             


Lys Asn Thr Tyr Arg Leu Val Thr Asp Gly Ala Leu Asp Arg Glu Gln 
    370                 375                 380                 


Ile Pro Glu Tyr Asn Val Thr Ile Thr Ala Thr Asp Lys Gly Asn Pro 
385                 390                 395                 400 


Pro Leu Ser Ser Ser Lys Thr Ile Thr Leu His Ile Leu Asp Val Asn 
                405                 410                 415     


Asp Asn Val Pro Val Phe His Gln Ala Ser Tyr Thr Val His Val Ala 
            420                 425                 430         


Glu Asn Asn Pro Pro Gly Ala Ser Ile Ala His Val Arg Ala Ser Asp 
        435                 440                 445             


Pro Asp Leu Gly Pro Asn Gly Leu Val Ser Tyr Tyr Ile Val Ala Ser 
    450                 455                 460                 


Asp Leu Glu Pro Arg Glu Leu Ser Ser Tyr Val Ser Val Ser Ala Arg 
465                 470                 475                 480 


Ser Gly Val Val Phe Ala Gln Arg Ala Phe Asp His Glu Gln Leu Arg 
                485                 490                 495     


Ala Phe Glu Leu Thr Leu Gln Ala Arg Asp Gln Gly Ser Pro Thr Leu 
            500                 505                 510         


Ser Ala Asn Val Ser Leu Arg Val Leu Val Asp Asp Arg Asn Asp Asn 
        515                 520                 525             


Ala Pro Leu Val Leu Tyr Pro Ala Leu Gly Pro Glu Gly Ser Ala Leu 
    530                 535                 540                 


Phe Asp Met Val Pro Arg Ser Ala Glu Pro Gly Tyr Leu Val Thr Lys 
545                 550                 555                 560 


Val Val Ala Val Asp Ala Asp Ser Gly Tyr Asn Ala Trp Leu Ser Tyr 
                565                 570                 575     


His Ile Val Gln Ala Ser Glu Pro Gly Leu Phe Ser Leu Gly Leu Arg 
            580                 585                 590         


Thr Gly Glu Val Arg Thr Ala Arg Thr Leu Gly Asp Arg Glu Ala Ala 
        595                 600                 605             


Arg Gln Arg Leu Leu Val Thr Val Arg Asp Gly Gly Gln Gln Pro Leu 
    610                 615                 620                 


Ser Ala Thr Val Met Leu His Leu Ile Phe Ala Asp Ser Leu Gln Glu 
625                 630                 635                 640 


Ile Gln Pro Asp Leu Ser Asp Arg Pro Thr Pro Ser Asp Pro Gln Ala 
                645                 650                 655     


Glu Leu Gln Phe His 
            660     


<210>  1063
<211>  661
<212>  PRT
<213>  Homo Sapiens

<400>  1063

Glu Pro Ile Arg Tyr Ser Ile Pro Glu Glu Leu Ala Lys Gly Ser Val 
1               5                   10                  15      


Val Gly Asn Leu Ala Lys Asp Leu Gly Leu Ser Val Leu Asp Val Ser 
            20                  25                  30          


Ala Arg Lys Leu Arg Val Ser Ala Glu Lys Leu His Phe Ser Val Asp 
        35                  40                  45              


Ala Glu Ser Gly Asp Leu Leu Val Lys Asn Arg Ile Asp Arg Glu Gln 
    50                  55                  60                  


Ile Cys Lys Glu Arg Arg Arg Cys Glu Leu Gln Leu Glu Ala Val Val 
65                  70                  75                  80  


Glu Asn Pro Leu Asn Ile Phe His Val Ile Val Val Ile Glu Asp Val 
                85                  90                  95      


Asn Asp His Ala Pro Gln Phe Asp Lys Lys Glu Ile His Leu Glu Ile 
            100                 105                 110         


Phe Glu Ser Ala Ser Ala Gly Thr Arg Leu Ser Leu Asp Pro Ala Thr 
        115                 120                 125             


Asp Pro Asp Ile Asn Ile Asn Ser Ile Lys Asp Tyr Lys Ile Asn Ser 
    130                 135                 140                 


Asn Pro Tyr Phe Ser Leu Met Val Arg Val Asn Ser Asp Gly Gly Lys 
145                 150                 155                 160 


Tyr Pro Glu Leu Ser Leu Glu Lys Leu Leu Asp Arg Glu Glu Gln Arg 
                165                 170                 175     


Ser His Ser Leu Ile Leu Thr Ala Leu Asp Gly Gly Asp Pro Pro Arg 
            180                 185                 190         


Ser Ala Thr Ala His Ile Glu Ile Ser Val Lys Asp Thr Asn Asp Asn 
        195                 200                 205             


Pro Pro Val Phe Ser Arg Asp Glu Tyr Arg Ile Ser Leu Ser Glu Asn 
    210                 215                 220                 


Leu Pro Pro Gly Ser Pro Val Leu Gln Val Thr Ala Thr Asp Gln Asp 
225                 230                 235                 240 


Glu Gly Val Asn Ala Glu Ile Asn Tyr Tyr Phe Arg Ser Thr Ala Gln 
                245                 250                 255     


Ser Thr Lys His Met Phe Ser Leu Asp Glu Lys Thr Gly Met Ile Lys 
            260                 265                 270         


Asn Asn Gln Ser Phe Asp Phe Glu Asp Val Glu Arg Tyr Thr Met Glu 
        275                 280                 285             


Val Glu Ala Lys Asp Gly Gly Gly Leu Ser Thr Gln Cys Lys Val Ile 
    290                 295                 300                 


Ile Glu Ile Leu Asp Glu Asn Asp Asn Ser Pro Glu Ile Ile Ile Thr 
305                 310                 315                 320 


Ser Leu Ser Asp Gln Ile Leu Glu Asn Ser Pro Pro Gly Met Val Val 
                325                 330                 335     


Ala Leu Phe Lys Thr Arg Asp Leu Asp Phe Gly Gly Asn Gly Glu Val 
            340                 345                 350         


Arg Cys Asn Ile Glu Thr Asp Ile Pro Phe Lys Ile Tyr Ser Ser Ser 
        355                 360                 365             


Asn Asn Tyr Tyr Lys Leu Val Thr Asp Gly Ala Leu Asp Arg Glu Gln 
    370                 375                 380                 


Thr Pro Glu Tyr Asn Val Thr Ile Val Ala Thr Asp Arg Gly Lys Pro 
385                 390                 395                 400 


Pro Leu Ser Ser Ser Arg Ser Ile Thr Leu Tyr Val Ala Asp Ile Asn 
                405                 410                 415     


Asp Asn Ala Pro Val Phe Asp Gln Thr Ser Tyr Val Val His Val Ala 
            420                 425                 430         


Glu Asn Asn Pro Pro Gly Ala Ser Ile Ala Gln Val Ser Ala Ser Asp 
        435                 440                 445             


Pro Asp Leu Gly Leu Asn Gly His Ile Ser Tyr Ser Ile Val Ala Ser 
    450                 455                 460                 


Asp Leu Glu Pro Leu Ala Val Ser Ser Tyr Val Ser Val Ser Ala Gln 
465                 470                 475                 480 


Ser Gly Val Val Phe Ala Gln Arg Ala Phe Asp His Glu Gln Leu Arg 
                485                 490                 495     


Ala Phe Ala Leu Thr Leu Gln Ala Arg Asp His Gly Ser Pro Thr Leu 
            500                 505                 510         


Ser Ala Asn Val Ser Leu Arg Val Leu Val Gly Asp Arg Asn Asp Asn 
        515                 520                 525             


Ala Pro Arg Val Leu Tyr Pro Ala Leu Gly Pro Asp Gly Ser Ala Phe 
    530                 535                 540                 


Phe Asp Met Val Pro Arg Ser Ala Glu Pro Gly Tyr Leu Val Thr Lys 
545                 550                 555                 560 


Val Val Ala Val Asp Ala Asp Ser Gly His Asn Ala Trp Leu Ser Tyr 
                565                 570                 575     


His Val Leu Gln Ala Ser Glu Pro Gly Leu Phe Ser Leu Gly Leu Arg 
            580                 585                 590         


Thr Gly Glu Val Arg Thr Ala Arg Ala Leu Gly Asp Arg Asp Ala Ala 
        595                 600                 605             


Arg Gln Arg Leu Leu Val Ala Val Arg Asp Gly Gly Gln Pro Pro Leu 
    610                 615                 620                 


Ser Ala Thr Ala Thr Leu His Leu Val Phe Ala Asp Asn Leu Gln Glu 
625                 630                 635                 640 


Ile Leu Pro Asp Leu Ser Asp Arg Pro Val Leu Ser Asp Pro Gln Ala 
                645                 650                 655     


Glu Leu Gln Phe Tyr 
            660     


<210>  1064
<211>  662
<212>  PRT
<213>  Homo Sapiens

<400>  1064

Val Ile His Tyr Glu Ile Pro Glu Glu Arg Glu Lys Gly Phe Ala Val 
1               5                   10                  15      


Gly Asn Val Val Ala Asn Leu Gly Leu Asp Leu Gly Ser Leu Ser Ala 
            20                  25                  30          


Arg Arg Phe Arg Val Val Ser Gly Ala Ser Arg Arg Phe Phe Glu Val 
        35                  40                  45              


Asn Arg Glu Thr Gly Glu Met Phe Val Asn Asp Arg Leu Asp Arg Glu 
    50                  55                  60                  


Glu Leu Cys Gly Thr Leu Pro Ser Cys Thr Val Thr Leu Glu Leu Val 
65                  70                  75                  80  


Val Glu Asn Pro Leu Glu Leu Phe Ser Val Glu Val Val Ile Gln Asp 
                85                  90                  95      


Ile Asn Asp Asn Asn Pro Ala Phe Pro Thr Gln Glu Met Lys Leu Glu 
            100                 105                 110         


Ile Ser Glu Ala Val Ala Pro Gly Thr Arg Phe Pro Leu Glu Ser Ala 
        115                 120                 125             


His Asp Pro Asp Val Gly Ser Asn Ser Leu Gln Thr Tyr Glu Leu Ser 
    130                 135                 140                 


Arg Asn Glu Tyr Phe Ala Leu Arg Val Gln Thr Arg Glu Asp Ser Thr 
145                 150                 155                 160 


Lys Tyr Ala Glu Leu Val Leu Glu Arg Ala Leu Asp Arg Glu Arg Glu 
                165                 170                 175     


Pro Ser Leu Gln Leu Val Leu Thr Ala Leu Asp Gly Gly Thr Pro Ala 
            180                 185                 190         


Leu Ser Ala Ser Leu Pro Ile His Ile Lys Val Leu Asp Ala Asn Asp 
        195                 200                 205             


Asn Ala Pro Val Phe Asn Gln Ser Leu Tyr Arg Ala Arg Val Leu Glu 
    210                 215                 220                 


Asp Ala Pro Ser Gly Thr Arg Val Val Gln Val Leu Ala Thr Asp Leu 
225                 230                 235                 240 


Asp Glu Gly Pro Asn Gly Glu Ile Ile Tyr Ser Phe Gly Ser His Asn 
                245                 250                 255     


Arg Ala Gly Val Arg Gln Leu Phe Ala Leu Asp Leu Val Thr Gly Met 
            260                 265                 270         


Leu Thr Ile Lys Gly Arg Leu Asp Phe Glu Asp Thr Lys Leu His Glu 
        275                 280                 285             


Ile Tyr Ile Gln Ala Lys Asp Lys Gly Ala Asn Pro Glu Gly Ala His 
    290                 295                 300                 


Cys Lys Val Leu Val Glu Val Val Asp Val Asn Asp Asn Ala Pro Glu 
305                 310                 315                 320 


Ile Thr Val Thr Ser Val Tyr Ser Pro Val Pro Glu Asp Ala Pro Leu 
                325                 330                 335     


Gly Thr Val Ile Ala Leu Leu Ser Val Thr Asp Leu Asp Ala Gly Glu 
            340                 345                 350         


Asn Gly Leu Val Thr Cys Glu Val Pro Pro Gly Leu Pro Phe Ser Leu 
        355                 360                 365             


Thr Ser Ser Leu Lys Asn Tyr Phe Thr Leu Lys Thr Ser Ala Asp Leu 
    370                 375                 380                 


Asp Arg Glu Thr Val Pro Glu Tyr Asn Leu Ser Ile Thr Ala Arg Asp 
385                 390                 395                 400 


Ala Gly Thr Pro Ser Leu Ser Ala Leu Thr Ile Val Arg Val Gln Val 
                405                 410                 415     


Ser Asp Ile Asn Asp Asn Pro Pro Gln Ser Ser Gln Ser Ser Tyr Asp 
            420                 425                 430         


Val Tyr Ile Glu Glu Asn Asn Leu Pro Gly Ala Pro Ile Leu Asn Leu 
        435                 440                 445             


Ser Val Trp Asp Pro Asp Ala Pro Gln Asn Ala Arg Leu Ser Phe Phe 
    450                 455                 460                 


Leu Leu Glu Gln Gly Ala Glu Thr Gly Leu Val Gly Arg Tyr Phe Thr 
465                 470                 475                 480 


Ile Asn Arg Asp Asn Gly Ile Val Ser Ser Leu Val Pro Leu Asp Tyr 
                485                 490                 495     


Glu Asp Arg Arg Glu Phe Glu Leu Thr Ala His Ile Ser Asp Gly Gly 
            500                 505                 510         


Thr Pro Val Leu Ala Thr Asn Ile Ser Val Asn Ile Phe Val Thr Asp 
        515                 520                 525             


Arg Asn Asp Asn Ala Pro Gln Val Leu Tyr Pro Arg Pro Gly Gly Ser 
    530                 535                 540                 


Ser Val Glu Met Leu Pro Arg Gly Thr Ser Ala Gly His Leu Val Ser 
545                 550                 555                 560 


Arg Val Val Gly Trp Asp Ala Asp Ala Gly His Asn Ala Trp Leu Ser 
                565                 570                 575     


Tyr Ser Leu Leu Gly Ser Pro Asn Gln Ser Leu Phe Ala Ile Gly Leu 
            580                 585                 590         


His Thr Gly Gln Ile Ser Thr Ala Arg Pro Val Gln Asp Thr Asp Ser 
        595                 600                 605             


Pro Arg Gln Thr Leu Thr Val Leu Ile Lys Asp Asn Gly Glu Pro Ser 
    610                 615                 620                 


Leu Ser Thr Thr Ala Thr Leu Thr Val Ser Val Thr Glu Asp Ser Pro 
625                 630                 635                 640 


Glu Ala Arg Ala Glu Phe Pro Ser Gly Ser Ala Pro Arg Glu Gln Lys 
                645                 650                 655     


Lys Asn Leu Thr Phe Tyr 
            660         


<210>  1065
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  1065

Ala Arg Pro Val Lys Glu Pro Arg Gly Leu Ser Ala Ala Ser Pro Pro 
1               5                   10                  15      


Leu Ala Glu Thr Gly Ala Pro Arg Arg Phe Arg Arg Ser Val Pro Arg 
            20                  25                  30          


Gly Glu Ala Ala Gly Ala Val Gln Glu Leu Ala Arg Ala Leu Ala His 
        35                  40                  45              


Leu Leu Glu Ala Glu Arg Gln Glu Arg Ala Arg Ala Glu Ala Gln Glu 
    50                  55                  60                  


Ala Glu Asp Gln Gln Ala Arg Val Leu Ala Gln Leu Leu Arg Val Trp 
65                  70                  75                  80  


Gly Ala Pro Arg Asn Ser Asp Pro Ala Leu Gly Leu Asp Asp Asp Pro 
                85                  90                  95      


Asp Ala Pro Ala Ala Gln Leu Ala Arg Ala Leu Leu Arg Ala Arg Leu 
            100                 105                 110         


Asp Pro Ala Ala Leu Ala Ala Gln Leu Val Pro Ala Pro Val Pro Ala 
        115                 120                 125             


Ala Ala Leu Arg Pro Arg Pro Pro Val Tyr Asp Asp Gly Pro Ala Gly 
    130                 135                 140                 


Pro Asp Ala Glu Glu Ala Gly Asp Glu Thr Pro Asp Val Asp Pro Glu 
145                 150                 155                 160 


Leu Leu Arg Tyr Leu Leu Gly Arg Ile Leu Ala Gly Ser Ala Asp Ser 
                165                 170                 175     


Glu Gly Val Ala Ala Pro Arg Arg Leu Arg Arg Ala Ala Asp His Asp 
            180                 185                 190         


Val Gly Ser Glu Leu Pro Pro Glu Gly Val Leu Gly Ala Leu Leu Arg 
        195                 200                 205             


Val Lys Arg Leu Glu Thr Pro Ala Pro Gln Val Pro Ala Arg Arg Leu 
    210                 215                 220                 


Leu Pro Pro 
225         


<210>  1066
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  1066

Gly Ala Gly Trp Gln Leu Phe Cys Arg Thr Val Trp Ser Ala His Ser 
1               5                   10                  15      


Gly Pro Thr Arg Met Ala Thr Ala Ile Ala Arg Cys Ala Pro Asp Glu 
            20                  25                  30          


Glu Leu Leu Ser Cys Ser Ser Phe Ser Arg Ser Gly Lys Arg Arg Gly 
        35                  40                  45              


Glu Arg Met Glu Ala Gln Gly Gly Lys Leu Val Cys Arg Ala His Asn 
    50                  55                  60                  


Ala Phe Gly Gly Glu Gly Val Tyr Ala Ile Ala Arg Cys Cys Leu Leu 
65                  70                  75                  80  


Pro Gln Ala Asn Cys Ser Val His Thr Ala Pro Pro Ala Glu Ala Ser 
                85                  90                  95      


Met Gly Thr Arg Val His Cys His Gln Gln Gly His Val Leu Thr Gly 
            100                 105                 110         


Cys Ser Ser His Trp Glu Val Glu Asp Leu Gly Thr His Lys Pro Pro 
        115                 120                 125             


Val Leu Arg Pro Arg Gly Gln Pro Asn Gln Cys Val Gly His Arg Glu 
    130                 135                 140                 


Ala Ser Ile His Ala Ser Cys Cys His Ala Pro Gly Leu Glu Cys Lys 
145                 150                 155                 160 


Val Lys Glu His Gly Ile Pro Ala Pro Gln Glu Gln Val Thr Val Ala 
                165                 170                 175     


Cys Glu Glu Gly Trp Thr Leu Thr Gly Cys Ser Ala Leu Pro Gly Thr 
            180                 185                 190         


Ser His Val Leu Gly Ala Tyr Ala Val Asp Asn Thr Cys Val Val Arg 
        195                 200                 205             


Ser Arg Asp Val Ser Thr Thr Gly Ser Thr Ser Glu Glu Ala Val Thr 
    210                 215                 220                 


Ala Val Ala Ile Cys Cys Arg Ser Arg His Leu Ala Gln Ala Ser Gln 
225                 230                 235                 240 


Glu Leu Gln 
            


<210>  1067
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  1067

Pro Gly Trp Phe Leu Asp Ser Pro Asp Arg Pro Trp Asn Pro Pro Thr 
1               5                   10                  15      


Phe Ser Pro Ala Leu Leu Val Val Thr Glu Gly Asp Asn Ala Thr Phe 
            20                  25                  30          


Thr Cys Ser Phe Ser Asn Thr Ser Glu Ser Phe Val Leu Asn Trp Tyr 
        35                  40                  45              


Arg Met Ser Pro Ser Asn Gln Thr Asp Lys Leu Ala Ala Phe Pro Glu 
    50                  55                  60                  


Asp Arg Ser Gln Pro Gly Gln Asp Cys Arg Phe Arg Val Thr Gln Leu 
65                  70                  75                  80  


Pro Asn Gly Arg Asp Phe His Met Ser Val Val Arg Ala Arg Arg Asn 
                85                  90                  95      


Asp Ser Gly Thr Tyr Leu Cys Gly Ala Ile Ser Leu Ala Pro Lys Ala 
            100                 105                 110         


Gln Ile Lys Glu Ser Leu Arg Ala Glu Leu Arg Val Thr Glu Arg Arg 
        115                 120                 125             


Ala Glu Val Pro Thr Ala His Pro Ser Pro Ser Pro Arg Pro Ala Gly 
    130                 135                 140                 


Gln Phe Gln Thr Leu Val 
145                 150 


<210>  1068
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  1068

Leu Phe Thr Val Thr Val Pro Lys Glu Leu Tyr Ile Ile Glu His Gly 
1               5                   10                  15      


Ser Asn Val Thr Leu Glu Cys Asn Phe Asp Thr Gly Ser His Val Asn 
            20                  25                  30          


Leu Gly Ala Ile Thr Ala Ser Leu Gln Lys Val Glu Asn Asp Thr Ser 
        35                  40                  45              


Pro His Arg Glu Arg Ala Thr Leu Leu Glu Glu Gln Leu Pro Leu Gly 
    50                  55                  60                  


Lys Ala Ser Phe His Ile Pro Gln Val Gln Val Arg Asp Glu Gly Gln 
65                  70                  75                  80  


Tyr Gln Cys Ile Ile Ile Tyr Gly Val Ala Trp Asp Tyr Lys Tyr Leu 
                85                  90                  95      


Thr Leu Lys Val Lys Ala Ser Tyr Arg Lys Ile Asn Thr His Ile Leu 
            100                 105                 110         


Lys Val Pro Glu Thr Asp Glu Val Glu Leu Thr Cys Gln Ala Thr Gly 
        115                 120                 125             


Tyr Pro Leu Ala Glu Val Ser Trp Pro Asn Val Ser Val Pro Ala Asn 
    130                 135                 140                 


Thr Ser His Ser Arg Thr Pro Glu Gly Leu Tyr Gln Val Thr Ser Val 
145                 150                 155                 160 


Leu Arg Leu Lys Pro Pro Pro Gly Arg Asn Phe Ser Cys Val Phe Trp 
                165                 170                 175     


Asn Thr His Val Arg Glu Leu Thr Leu Ala Ser Ile Asp Leu Gln Ser 
            180                 185                 190         


Gln Met Glu Pro Arg Thr His Pro Thr 
        195                 200     


<210>  1069
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  1069

Ser Ile Glu Glu Ala Val Pro Ala Val Cys Lys Thr Arg Thr Val Ile 
1               5                   10                  15      


Tyr Glu Ile Pro Arg Ser Gln Val Asp Pro Thr Ser Ala Asn Phe Leu 
            20                  25                  30          


Ile Trp Pro Pro Cys Val Glu Val Lys Arg Cys Thr Gly Cys Cys Asn 
        35                  40                  45              


Thr Ser Ser Val Lys Cys Gln Pro Ser Arg Val His His Arg Ser Val 
    50                  55                  60                  


Lys Val Ala Lys Val Glu Tyr Val Arg Lys Lys Pro Lys Leu Lys Glu 
65                  70                  75                  80  


Val Gln Val Arg Leu Glu Glu His Leu Glu Cys Ala Cys Ala Thr Thr 
                85                  90                  95      


Ser Leu Asn Pro Asp Tyr Arg Glu Glu Asp Thr Asp Val Arg 
            100                 105                 110 


<210>  1070
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  1070

Ser Leu Gly Ser Leu Thr Ile Ala Glu Pro Ala Met Ile Ala Glu Cys 
1               5                   10                  15      


Lys Thr Arg Thr Glu Val Phe Glu Ile Ser Arg Arg Leu Ile Asp Arg 
            20                  25                  30          


Thr Asn Ala Asn Phe Leu Val Trp Pro Pro Cys Val Glu Val Gln Arg 
        35                  40                  45              


Cys Ser Gly Cys Cys Asn Asn Arg Asn Val Gln Cys Arg Pro Thr Gln 
    50                  55                  60                  


Val Gln Leu Arg Pro Val Gln Val Arg Lys Ile Glu Ile Val Arg Lys 
65                  70                  75                  80  


Lys Pro Ile Phe Lys Lys Ala Thr Val Thr Leu Glu Asp His Leu Ala 
                85                  90                  95      


Cys Lys Cys Glu Thr Val Ala Ala Ala Arg Pro Val Thr 
            100                 105                 


<210>  1071
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  1071

Glu Ser Asn Leu Ser Ser Lys Phe Gln Phe Ser Ser Asn Lys Glu Gln 
1               5                   10                  15      


Asn Gly Val Gln Asp Pro Gln His Glu Arg Ile Ile Thr Val Ser Thr 
            20                  25                  30          


Asn Gly Ser Ile His Ser Pro Arg Phe Pro His Thr Tyr Pro Arg Asn 
        35                  40                  45              


Thr Val Leu Val Trp Arg Leu Val Ala Val Glu Glu Asn Val Trp Ile 
    50                  55                  60                  


Gln Leu Thr Phe Asp Glu Arg Phe Gly Leu Glu Asp Pro Glu Asp Asp 
65                  70                  75                  80  


Ile Cys Lys Tyr Asp Phe Val Glu Val Glu Glu Pro Ser Asp Gly Thr 
                85                  90                  95      


Ile Leu Gly Arg Trp Cys Gly Ser Gly Thr Val Pro Gly Lys Gln Ile 
            100                 105                 110         


Ser Lys Gly Asn Gln Ile Arg Ile Arg Phe Val Ser Asp Glu Tyr Phe 
        115                 120                 125             


Pro Ser Glu Pro Gly Phe Cys Ile His Tyr Asn Ile Val Met Pro Gln 
    130                 135                 140                 


Phe Thr Glu Ala Val Ser Pro Ser Val Leu Pro Pro Ser Ala Leu Pro 
145                 150                 155                 160 


Leu Asp Leu Leu Asn Asn Ala Ile Thr Ala Phe Ser Thr Leu Glu Asp 
                165                 170                 175     


Leu Ile Arg Tyr Leu Glu Pro Glu Arg Trp Gln Leu Asp Leu Glu Asp 
            180                 185                 190         


Leu Tyr Arg Pro Thr Trp Gln Leu Leu Gly Lys Ala Phe Val Phe Gly 
        195                 200                 205             


Arg Lys Ser Arg Val Val Asp Leu Asn Leu Leu Thr Glu Glu Val Arg 
    210                 215                 220                 


Leu Tyr Ser Cys Thr Pro Arg Asn Phe Ser Val Ser Ile Arg Glu Glu 
225                 230                 235                 240 


Leu Lys Arg Thr Asp Thr Ile Phe Trp Pro Gly Cys Leu Leu Val Lys 
                245                 250                 255     


Arg Cys Gly Gly Asn Cys Ala Cys Cys Leu His Asn Cys Asn Glu Cys 
            260                 265                 270         


Gln Cys Val Pro Ser Lys Val Thr Lys Lys Tyr His Glu Val Leu Gln 
        275                 280                 285             


Leu Arg Pro Lys Thr Gly Val Arg Gly Leu His Lys Ser Leu Thr Asp 
    290                 295                 300                 


Val Ala Leu Glu His His Glu Glu Cys Asp Cys Val Cys Arg Gly Ser 
305                 310                 315                 320 


Thr Gly Gly 
            


<210>  1072
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1072

Ser Tyr His Asp Arg Lys Ser Lys Val Asp Leu Asp Arg Leu Asn Asp 
1               5                   10                  15      


Asp Ala Lys Arg Tyr Ser Cys Thr Pro Arg Asn Tyr Ser Val Asn Ile 
            20                  25                  30          


Arg Glu Glu Leu Lys Leu Ala Asn Val Val Phe Phe Pro Arg Cys Leu 
        35                  40                  45              


Leu Val Gln Arg Cys Gly Gly Asn Cys Gly Cys Gly Thr Val Asn Trp 
    50                  55                  60                  


Arg Ser Cys Thr Cys Asn Ser Gly Lys Thr Val Lys Lys Tyr His Glu 
65                  70                  75                  80  


Val Leu Gln Phe Glu Pro Gly His Ile Lys Arg Arg Gly Arg Ala Lys 
                85                  90                  95      


Thr Met Ala Leu Val Asp Ile Gln Leu Asp His His Glu Arg Cys Asp 
            100                 105                 110         


Cys Ile Cys Ser Ser Arg Pro Pro Arg 
        115                 120     


<210>  1073
<211>  505
<212>  PRT
<213>  Homo Sapiens

<400>  1073

Gln Leu Ser Leu Pro Ser Ile Leu Pro Asn Glu Asn Glu Lys Val Val 
1               5                   10                  15      


Gln Leu Asn Ser Ser Phe Ser Leu Arg Cys Phe Gly Glu Ser Glu Val 
            20                  25                  30          


Ser Trp Gln Tyr Pro Met Ser Glu Glu Glu Ser Ser Asp Val Glu Ile 
        35                  40                  45              


Arg Asn Glu Glu Asn Asn Ser Gly Leu Phe Val Thr Val Leu Glu Val 
    50                  55                  60                  


Ser Ser Ala Ser Ala Ala His Thr Gly Leu Tyr Thr Cys Tyr Tyr Asn 
65                  70                  75                  80  


His Thr Gln Thr Glu Glu Asn Glu Leu Glu Gly Arg His Ile Tyr Ile 
                85                  90                  95      


Tyr Val Pro Asp Pro Asp Val Ala Phe Val Pro Leu Gly Met Thr Asp 
            100                 105                 110         


Tyr Leu Val Ile Val Glu Asp Asp Asp Ser Ala Ile Ile Pro Cys Arg 
        115                 120                 125             


Thr Thr Asp Pro Glu Thr Pro Val Thr Leu His Asn Ser Glu Gly Val 
    130                 135                 140                 


Val Pro Ala Ser Tyr Asp Ser Arg Gln Gly Phe Asn Gly Thr Phe Thr 
145                 150                 155                 160 


Val Gly Pro Tyr Ile Cys Glu Ala Thr Val Lys Gly Lys Lys Phe Gln 
                165                 170                 175     


Thr Ile Pro Phe Asn Val Tyr Ala Leu Lys Ala Thr Ser Glu Leu Asp 
            180                 185                 190         


Leu Glu Met Glu Ala Leu Lys Thr Val Tyr Lys Ser Gly Glu Thr Ile 
        195                 200                 205             


Val Val Thr Cys Ala Val Phe Asn Asn Glu Val Val Asp Leu Gln Trp 
    210                 215                 220                 


Thr Tyr Pro Gly Glu Val Lys Gly Lys Gly Ile Thr Met Leu Glu Glu 
225                 230                 235                 240 


Ile Lys Val Pro Ser Ile Lys Leu Val Tyr Thr Leu Thr Val Pro Glu 
                245                 250                 255     


Ala Thr Val Lys Asp Ser Gly Asp Tyr Glu Cys Ala Ala Arg Gln Ala 
            260                 265                 270         


Thr Arg Glu Val Lys Glu Met Lys Lys Val Thr Ile Ser Val His Glu 
        275                 280                 285             


Lys Gly Phe Ile Glu Ile Lys Pro Thr Phe Ser Gln Leu Glu Ala Val 
    290                 295                 300                 


Asn Leu His Glu Val Lys His Phe Val Val Glu Val Arg Ala Tyr Pro 
305                 310                 315                 320 


Pro Pro Arg Ile Ser Trp Leu Lys Asn Asn Leu Thr Leu Ile Glu Asn 
                325                 330                 335     


Leu Thr Glu Ile Thr Thr Asp Val Glu Lys Ile Gln Glu Ile Arg Tyr 
            340                 345                 350         


Arg Ser Lys Leu Lys Leu Ile Arg Ala Lys Glu Glu Asp Ser Gly His 
        355                 360                 365             


Tyr Thr Ile Val Ala Gln Asn Glu Asp Ala Val Lys Ser Tyr Thr Phe 
    370                 375                 380                 


Glu Leu Leu Thr Gln Val Pro Ser Ser Ile Leu Asp Leu Val Asp Asp 
385                 390                 395                 400 


His His Gly Ser Thr Gly Gly Gln Thr Val Arg Cys Thr Ala Glu Gly 
                405                 410                 415     


Thr Pro Leu Pro Asp Ile Glu Trp Met Ile Cys Lys Asp Ile Lys Lys 
            420                 425                 430         


Cys Asn Asn Glu Thr Ser Trp Thr Ile Leu Ala Asn Asn Val Ser Asn 
        435                 440                 445             


Ile Ile Thr Glu Ile His Ser Arg Asp Arg Ser Thr Val Glu Gly Arg 
    450                 455                 460                 


Val Thr Phe Ala Lys Val Glu Glu Thr Ile Ala Val Arg Cys Leu Ala 
465                 470                 475                 480 


Lys Asn Leu Leu Gly Ala Glu Asn Arg Glu Leu Lys Leu Val Ala Pro 
                485                 490                 495     


Thr Leu Arg Ser Glu Leu Thr Val Ala 
            500                 505 


<210>  1074
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  1074

Leu Val Val Thr Pro Pro Gly Pro Glu Leu Val Leu Asn Val Ser Ser 
1               5                   10                  15      


Thr Phe Val Leu Thr Cys Ser Gly Ser Ala Pro Val Val Trp Glu Arg 
            20                  25                  30          


Met Ser Gln Glu Pro Pro Gln Glu Met Ala Lys Ala Gln Asp Gly Thr 
        35                  40                  45              


Phe Ser Ser Val Leu Thr Leu Thr Asn Leu Thr Gly Leu Asp Thr Gly 
    50                  55                  60                  


Glu Tyr Phe Cys Thr His Asn Asp Ser Arg Gly Leu Glu Thr Asp Glu 
65                  70                  75                  80  


Arg Lys Arg Leu Tyr Ile Phe Val Pro Asp Pro Thr Val Gly Phe Leu 
                85                  90                  95      


Pro Asn Asp Ala Glu Glu Leu Phe Ile Phe Leu Thr Glu Ile Thr Glu 
            100                 105                 110         


Ile Thr Ile Pro Cys Arg Val Thr Asp Pro Gln Leu Val Val Thr Leu 
        115                 120                 125             


His Glu Lys Lys Gly Asp Val Ala Leu Pro Val Pro Tyr Asp His Gln 
    130                 135                 140                 


Arg Gly Phe Phe Gly Ile Phe Glu Asp Arg Ser Tyr Ile Cys Lys Thr 
145                 150                 155                 160 


Thr Ile Gly Asp Arg Glu Val Asp Ser Asp Ala Tyr Tyr Val Tyr Arg 
                165                 170                 175     


Leu Gln Val Ser Ser Ile Asn Val Ser Val Asn Ala Val Gln Thr Val 
            180                 185                 190         


Val Arg Gln Gly Glu Asn Ile Thr Leu Met Cys Ile Val Ile Gly Asn 
        195                 200                 205             


Glu Val Val Asn Phe Glu Trp Thr Tyr Pro Arg Lys Glu Ser Gly Arg 
    210                 215                 220                 


Leu Val Glu Pro Val Thr Asp Phe Leu Leu Asp Met Pro Tyr His Ile 
225                 230                 235                 240 


Arg Ser Ile Leu His Ile Pro Ser Ala Glu Leu Glu Asp Ser Gly Thr 
                245                 250                 255     


Tyr Thr Cys Asn Val Thr Glu Ser Val Asn Asp His Gln Asp Glu Lys 
            260                 265                 270         


Ala Ile Asn Ile Thr Val Val Glu Ser Gly Tyr Val Arg Leu Leu Gly 
        275                 280                 285             


Glu Val Gly Thr Leu Gln Phe Ala Glu Leu His Arg Ser Arg Thr Leu 
    290                 295                 300                 


Gln Val Val Phe Glu Ala Tyr Pro Pro Pro Thr Val Leu Trp Phe Lys 
305                 310                 315                 320 


Asp Asn Arg Thr Leu Gly Asp Ser Ser Ala Gly Glu Ile Ala Leu Ser 
                325                 330                 335     


Thr Arg Asn Val Ser Glu Thr Arg Tyr Val Ser Glu Leu Thr Leu Val 
            340                 345                 350         


Arg Val Lys Val Ala Glu Ala Gly His Tyr Thr Met Arg Ala Phe His 
        355                 360                 365             


Glu Asp Ala Glu Val Gln Leu Ser Phe Gln Leu Gln Ile Asn Val Pro 
    370                 375                 380                 


Val Arg Val Leu Glu Leu Ser Glu Ser His Pro Asp Ser Gly Glu Gln 
385                 390                 395                 400 


Thr Val Arg Cys Arg Gly Arg Gly Met Pro Gln Pro Asn Ile Ile Trp 
                405                 410                 415     


Ser Ala Cys Arg Asp Leu Lys Arg Cys Pro Arg Glu Leu Pro Pro Thr 
            420                 425                 430         


Leu Leu Gly Asn Ser Ser Glu Glu Glu Ser Gln Leu Glu Thr Asn Val 
        435                 440                 445             


Thr Tyr Trp Glu Glu Glu Gln Glu Phe Glu Val Val Ser Thr Leu Arg 
    450                 455                 460                 


Leu Gln His Val Asp Arg Pro Leu Ser Val Arg Cys Thr Leu Arg Asn 
465                 470                 475                 480 


Ala Val Gly Gln Asp Thr Gln Glu Val Ile Val Val Pro His Ser Leu 
                485                 490                 495     


Pro Phe Lys Val 
            500 


<210>  1075
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  1075

Gln His Leu Pro Lys Asn Lys Arg Pro Lys Glu Pro Gly Glu Asn Arg 
1               5                   10                  15      


Ile Lys Pro Thr Asn Lys Lys Val Lys Pro Lys Ile Pro Lys Met Lys 
            20                  25                  30          


Asp Arg Asp Ser Ala Asn Ser Ala Pro Lys Thr Gln Ser Ile Met Met 
        35                  40                  45              


Gln Val Leu Asp Lys Gly Arg Phe Gln Lys Pro Ala Ala Thr Leu Ser 
    50                  55                  60                  


Leu Leu Ala Gly Gln Thr Val Glu Leu Arg Cys Lys Gly Ser Arg Ile 
65                  70                  75                  80  


Gly Trp Ser Tyr Pro Ala Tyr Leu Asp Thr Phe Lys Asp Ser Arg Leu 
                85                  90                  95      


Ser Val Lys Gln Asn Glu Arg Tyr Gly Gln Leu Thr Leu Val Asn Ser 
            100                 105                 110         


Thr Ser Ala Asp Thr Gly Glu Phe Ser Cys Trp Val Gln Leu Cys Ser 
        115                 120                 125             


Gly Tyr Ile Cys Arg Lys Asp Glu Ala Lys Thr Gly Ser Thr Tyr Ile 
    130                 135                 140                 


Phe Phe Thr Glu Lys Gly Glu Leu Phe Val Pro Ser Pro Ser Tyr Phe 
145                 150                 155                 160 


Asp Val Val Tyr Leu Asn Pro Asp Arg Gln Ala Val Val Pro Cys Arg 
                165                 170                 175     


Val Thr Val Leu Ser Ala Lys Val Thr Leu His Arg Glu Phe Pro Ala 
            180                 185                 190         


Lys Glu Ile Pro Ala Asn Gly Thr Asp Ile Val Tyr Asp Met Lys Arg 
        195                 200                 205             


Gly Phe Val Tyr Leu Gln Pro His Ser Glu His Gln Gly Val Val Tyr 
    210                 215                 220                 


Cys Arg Ala Glu Ala Gly Gly Arg Ser Gln Ile Ser Val Lys Tyr Gln 
225                 230                 235                 240 


Leu Leu Tyr Val Ala Val Pro Ser Gly Pro Pro Ser Thr Thr Ile Leu 
                245                 250                 255     


Ala Ser Ser Asn Lys Val Lys Ser Gly Asp Asp Ile Ser Val Leu Cys 
            260                 265                 270         


Thr Val Leu Gly Glu Pro Asp Val Glu Val Glu Phe Thr Trp Ile Phe 
        275                 280                 285             


Pro Gly Gln Lys Asp Glu Arg Pro Val Thr Ile Gln Asp Thr Trp Arg 
    290                 295                 300                 


Leu Ile His Arg Gly Leu Gly His Thr Thr Arg Ile Ser Gln Ser Val 
305                 310                 315                 320 


Ile Thr Val Glu Asp Phe Glu Thr Ile Asp Ala Gly Tyr Tyr Ile Cys 
                325                 330                 335     


Thr Ala Gln Asn Leu Gln Gly Gln Thr Thr Val Ala Thr Thr Val Glu 
            340                 345                 350         


Phe Ser 
        


<210>  1076
<211>  574
<212>  PRT
<213>  Homo Sapiens

<400>  1076

Gln Glu Asn Ser Phe Thr Ile Asn Ser Val Asp Met Lys Ser Leu Pro 
1               5                   10                  15      


Asp Trp Thr Val Gln Asn Gly Lys Asn Leu Thr Leu Gln Cys Phe Ala 
            20                  25                  30          


Asp Val Ser Thr Thr Ser His Val Lys Pro Gln His Gln Met Leu Phe 
        35                  40                  45              


Tyr Lys Asp Asp Val Leu Phe Tyr Asn Ile Ser Ser Met Lys Ser Thr 
    50                  55                  60                  


Glu Ser Tyr Phe Ile Pro Glu Val Arg Ile Tyr Asp Ser Gly Thr Tyr 
65                  70                  75                  80  


Lys Cys Thr Val Ile Val Asn Asn Lys Glu Lys Thr Thr Ala Glu Tyr 
                85                  90                  95      


Gln Val Leu Val Glu Gly Val Pro Ser Pro Arg Val Thr Leu Asp Lys 
            100                 105                 110         


Lys Glu Ala Ile Gln Gly Gly Ile Val Arg Val Asn Cys Ser Val Pro 
        115                 120                 125             


Glu Glu Lys Ala Pro Ile His Phe Thr Ile Glu Lys Leu Glu Leu Asn 
    130                 135                 140                 


Glu Lys Met Val Lys Leu Lys Arg Glu Lys Asn Ser Arg Asp Gln Asn 
145                 150                 155                 160 


Phe Val Ile Leu Glu Phe Pro Val Glu Glu Gln Asp Arg Val Leu Ser 
                165                 170                 175     


Phe Arg Cys Gln Ala Arg Ile Ile Ser Gly Ile His Met Gln Thr Ser 
            180                 185                 190         


Glu Ser Thr Lys Ser Glu Leu Val Thr Val Thr Glu Ser Phe Ser Thr 
        195                 200                 205             


Pro Lys Phe His Ile Ser Pro Thr Gly Met Ile Met Glu Gly Ala Gln 
    210                 215                 220                 


Leu His Ile Lys Cys Thr Ile Gln Val Thr His Leu Ala Gln Glu Phe 
225                 230                 235                 240 


Pro Glu Ile Ile Ile Gln Lys Asp Lys Ala Ile Val Ala His Asn Arg 
                245                 250                 255     


His Gly Asn Lys Ala Val Tyr Ser Val Met Ala Met Val Glu His Ser 
            260                 265                 270         


Gly Asn Tyr Thr Cys Lys Val Glu Ser Ser Arg Ile Ser Lys Val Ser 
        275                 280                 285             


Ser Ile Val Val Asn Ile Thr Glu Leu Phe Ser Lys Pro Glu Leu Glu 
    290                 295                 300                 


Ser Ser Phe Thr His Leu Asp Gln Gly Glu Arg Leu Asn Leu Ser Cys 
305                 310                 315                 320 


Ser Ile Pro Gly Ala Pro Pro Ala Asn Phe Thr Ile Gln Lys Glu Asp 
                325                 330                 335     


Thr Ile Val Ser Gln Thr Gln Asp Phe Thr Lys Ile Ala Ser Lys Ser 
            340                 345                 350         


Asp Ser Gly Thr Tyr Ile Cys Thr Ala Gly Ile Asp Lys Val Val Lys 
        355                 360                 365             


Lys Ser Asn Thr Val Gln Ile Val Val Cys Glu Met Leu Ser Gln Pro 
    370                 375                 380                 


Arg Ile Ser Tyr Asp Ala Gln Phe Glu Val Ile Lys Gly Gln Thr Ile 
385                 390                 395                 400 


Glu Val Arg Cys Glu Ser Ile Ser Gly Thr Leu Pro Ile Ser Tyr Gln 
                405                 410                 415     


Leu Leu Lys Thr Ser Lys Val Leu Glu Asn Ser Thr Lys Asn Ser Asn 
            420                 425                 430         


Asp Pro Ala Val Phe Lys Asp Asn Pro Thr Glu Asp Val Glu Tyr Gln 
        435                 440                 445             


Cys Val Ala Asp Asn Cys His Ser His Ala Lys Met Leu Ser Glu Val 
    450                 455                 460                 


Leu Arg Val Lys Val Ile Ala Pro Val Asp Glu Val Gln Ile Ser Ile 
465                 470                 475                 480 


Leu Ser Ser Lys Val Val Glu Ser Gly Glu Asp Ile Val Leu Gln Cys 
                485                 490                 495     


Ala Val Asn Glu Gly Ser Gly Pro Ile Thr Tyr Lys Phe Tyr Arg Glu 
            500                 505                 510         


Lys Glu Gly Lys Pro Phe Tyr Gln Met Thr Ser Asn Ala Thr Gln Ala 
        515                 520                 525             


Phe Trp Thr Lys Gln Lys Ala Asn Lys Glu Gln Glu Gly Glu Tyr Tyr 
    530                 535                 540                 


Cys Thr Ala Phe Asn Arg Ala Asn His Ala Ser Ser Val Pro Arg Ser 
545                 550                 555                 560 


Lys Ile Leu Thr Val Arg Val Ile Leu Ala Pro Trp Lys Lys 
                565                 570                 


<210>  1077
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  1077

Glu Ala Glu Glu Asp Gly Asp Leu Gln Cys Leu Cys Val Lys Thr Thr 
1               5                   10                  15      


Ser Gln Val Arg Pro Arg His Ile Thr Ser Leu Glu Val Ile Lys Ala 
            20                  25                  30          


Gly Pro His Cys Pro Thr Ala Gln Leu Ile Ala Thr Leu Lys Asn Gly 
        35                  40                  45              


Arg Lys Ile Cys Leu Asp Leu Gln Ala Pro Leu Tyr Lys Lys Ile Ile 
    50                  55                  60                  


Lys Lys Leu Leu Glu Ser 
65                  70  


<210>  1078
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  1078

Leu Pro Ala Val Pro Pro Gln Gln Trp Ala Leu Ser Ala Gly Asn Gly 
1               5                   10                  15      


Ser Ser Glu Val Glu Val Val Pro Phe Gln Glu Val Trp Gly Arg Ser 
            20                  25                  30          


Tyr Cys Arg Ala Leu Glu Arg Leu Val Asp Val Val Ser Glu Tyr Pro 
        35                  40                  45              


Ser Glu Val Glu His Met Phe Ser Pro Ser Cys Val Ser Leu Leu Arg 
    50                  55                  60                  


Cys Thr Gly Cys Cys Gly Asp Glu Asn Leu His Cys Val Pro Val Glu 
65                  70                  75                  80  


Thr Ala Asn Val Thr Met Gln Leu Leu Lys Ile Arg Ser Gly Asp Arg 
                85                  90                  95      


Pro Ser Tyr Val Glu Leu Thr Phe Ser Gln His Val Arg Cys Glu Cys 
            100                 105                 110         


Arg Pro Leu Arg Glu Lys Met Lys Pro Glu Arg Arg Arg Pro Lys Gly 
        115                 120                 125             


Arg Gly Lys Arg Arg Arg Glu Lys Gln Arg Pro Thr Asp Cys His Leu 
    130                 135                 140                 


Cys Gly Asp Ala Val Pro Arg Arg 
145                 150         


<210>  1079
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  1079

Gln Glu Thr Glu Asp Pro Ala Cys Cys Ser Pro Ile Val Pro Arg Asn 
1               5                   10                  15      


Glu Trp Lys Ala Leu Ala Ser Glu Cys Ala Gln His Leu Ser Leu Pro 
            20                  25                  30          


Leu Arg Tyr Val Val Val Ser His Thr Ala Gly Ser Ser Cys Asn Thr 
        35                  40                  45              


Pro Ala Ser Cys Gln Gln Gln Ala Arg Asn Val Gln His Tyr His Met 
    50                  55                  60                  


Lys Thr Leu Gly Trp Cys Asp Val Gly Tyr Asn Phe Leu Ile Gly Glu 
65                  70                  75                  80  


Asp Gly Leu Val Tyr Glu Gly Arg Gly Trp Asn Phe Thr Gly Ala His 
                85                  90                  95      


Ser Gly His Leu Trp Asn Pro Met Ser Ile Gly Ile Ser Phe Met Gly 
            100                 105                 110         


Asn Tyr Met Asp Arg Val Pro Thr Pro Gln Ala Ile Arg Ala Ala Gln 
        115                 120                 125             


Gly Leu Leu Ala Cys Gly Val Ala Gln Gly Ala Leu Arg Ser Asn Tyr 
    130                 135                 140                 


Val Leu Lys Gly His Arg Asp Val Gln Arg Thr Leu Ser Pro Gly Asn 
145                 150                 155                 160 


Gln Leu Tyr His Leu Ile Gln Asn Trp Pro His Tyr Arg Ser Pro 
                165                 170                 175 


<210>  1080
<211>  620
<212>  PRT
<213>  Homo Sapiens

<400>  1080

Lys Ser Pro Ile Phe Gly Pro Glu Glu Val Asn Ser Val Glu Gly Asn 
1               5                   10                  15      


Ser Val Ser Ile Thr Cys Tyr Tyr Pro Pro Thr Ser Val Asn Arg His 
            20                  25                  30          


Thr Arg Lys Tyr Trp Cys Arg Gln Gly Ala Arg Gly Gly Cys Ile Thr 
        35                  40                  45              


Leu Ile Ser Ser Glu Gly Tyr Val Ser Ser Lys Tyr Ala Gly Arg Ala 
    50                  55                  60                  


Asn Leu Thr Asn Phe Pro Glu Asn Gly Thr Phe Val Val Asn Ile Ala 
65                  70                  75                  80  


Gln Leu Ser Gln Asp Asp Ser Gly Arg Tyr Lys Cys Gly Leu Gly Ile 
                85                  90                  95      


Asn Ser Arg Gly Leu Ser Phe Asp Val Ser Leu Glu Val Ser Gln Gly 
            100                 105                 110         


Pro Gly Leu Leu Asn Asp Thr Lys Val Tyr Thr Val Asp Leu Gly Arg 
        115                 120                 125             


Thr Val Thr Ile Asn Cys Pro Phe Lys Thr Glu Asn Ala Gln Lys Arg 
    130                 135                 140                 


Lys Ser Leu Tyr Lys Gln Ile Gly Leu Tyr Pro Val Leu Val Ile Asp 
145                 150                 155                 160 


Ser Ser Gly Tyr Val Asn Pro Asn Tyr Thr Gly Arg Ile Arg Leu Asp 
                165                 170                 175     


Ile Gln Gly Thr Gly Gln Leu Leu Phe Ser Val Val Ile Asn Gln Leu 
            180                 185                 190         


Arg Leu Ser Asp Ala Gly Gln Tyr Leu Cys Gln Ala Gly Asp Asp Ser 
        195                 200                 205             


Asn Ser Asn Lys Lys Asn Ala Asp Leu Gln Val Leu Lys Pro Glu Pro 
    210                 215                 220                 


Glu Leu Val Tyr Glu Asp Leu Arg Gly Ser Val Thr Phe His Cys Ala 
225                 230                 235                 240 


Leu Gly Pro Glu Val Ala Asn Val Ala Lys Phe Leu Cys Arg Gln Ser 
                245                 250                 255     


Ser Gly Glu Asn Cys Asp Val Val Val Asn Thr Leu Gly Lys Arg Ala 
            260                 265                 270         


Pro Ala Phe Glu Gly Arg Ile Leu Leu Asn Pro Gln Asp Lys Asp Gly 
        275                 280                 285             


Ser Phe Ser Val Val Ile Thr Gly Leu Arg Lys Glu Asp Ala Gly Arg 
    290                 295                 300                 


Tyr Leu Cys Gly Ala His Ser Asp Gly Gln Leu Gln Glu Gly Ser Pro 
305                 310                 315                 320 


Ile Gln Ala Trp Gln Leu Phe Val Asn Glu Glu Ser Thr Ile Pro Arg 
                325                 330                 335     


Ser Pro Thr Val Val Lys Gly Val Ala Gly Gly Ser Val Ala Val Leu 
            340                 345                 350         


Cys Pro Tyr Asn Arg Lys Glu Ser Lys Ser Ile Lys Tyr Trp Cys Leu 
        355                 360                 365             


Trp Glu Gly Ala Gln Asn Gly Arg Cys Pro Leu Leu Val Asp Ser Glu 
    370                 375                 380                 


Gly Trp Val Lys Ala Gln Tyr Glu Gly Arg Leu Ser Leu Leu Glu Glu 
385                 390                 395                 400 


Pro Gly Asn Gly Thr Phe Thr Val Ile Leu Asn Gln Leu Thr Ser Arg 
                405                 410                 415     


Asp Ala Gly Phe Tyr Trp Cys Leu Thr Asn Gly Asp Thr Leu Trp Arg 
            420                 425                 430         


Thr Thr Val Glu Ile Lys Ile Ile Glu Gly Glu Pro Asn Leu Lys Val 
        435                 440                 445             


Pro Gly Asn Val Thr Ala Val Leu Gly Glu Thr Leu Lys Val Pro Cys 
    450                 455                 460                 


His Phe Pro Cys Lys Phe Ser Ser Tyr Glu Lys Tyr Trp Cys Lys Trp 
465                 470                 475                 480 


Asn Asn Thr Gly Cys Gln Ala Leu Pro Ser Gln Asp Glu Gly Pro Ser 
                485                 490                 495     


Lys Ala Phe Val Asn Cys Asp Glu Asn Ser Arg Leu Val Ser Leu Thr 
            500                 505                 510         


Leu Asn Leu Val Thr Arg Ala Asp Glu Gly Trp Tyr Trp Cys Gly Val 
        515                 520                 525             


Lys Gln Gly His Phe Tyr Gly Glu Thr Ala Ala Val Tyr Val Ala Val 
    530                 535                 540                 


Glu Glu Arg Lys Ala Ala Gly Ser Arg Asp Val Ser Leu Ala Lys Ala 
545                 550                 555                 560 


Asp Ala Ala Pro Asp Glu Lys Val Leu Asp Ser Gly Phe Arg Glu Ile 
                565                 570                 575     


Glu Asn Lys Ala Ile Gln Asp Pro Arg Leu Phe Ala Glu Glu Lys Ala 
            580                 585                 590         


Val Ala Asp Thr Arg Asp Gln Ala Asp Gly Ser Arg Ala Ser Val Asp 
        595                 600                 605             


Ser Gly Ser Ser Glu Glu Gln Gly Gly Ser Ser Arg 
    610                 615                 620 


<210>  1081
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  1081

Ser Gly Gly Cys Phe Trp Asp Asn Gly His Leu Tyr Arg Glu Asp Gln 
1               5                   10                  15      


Thr Ser Pro Ala Pro Gly Leu Arg Cys Leu Asn Trp Leu Asp Ala Gln 
            20                  25                  30          


Ser Gly Leu Ala Ser Ala Pro Val Ser Gly Ala Gly Asn His Ser Tyr 
        35                  40                  45              


Cys Arg Asn Pro Asp Glu Asp Pro Arg Gly Pro Trp Cys Tyr Val Ser 
    50                  55                  60                  


Gly Glu Ala Gly Val Pro Glu Lys Arg Pro Cys Glu Asp Leu Arg Cys 
65                  70                  75                  80  


Pro Glu Thr Thr Ser Gln Ala Leu Pro Ala Phe Thr Thr Glu Ile Gln 
                85                  90                  95      


Glu Ala Ser Glu Gly Pro Gly Ala Asp Glu Val Gln Val Phe Ala Pro 
            100                 105                 110         


Ala Asn Ala Leu Pro Ala Arg Ser Glu Ala Ala Ala Val Gln Pro Val 
        115                 120                 125             


Ile Gly Ile Ser Gln Arg Val Arg Met Asn Ser Lys Glu Lys Lys Asp 
    130                 135                 140                 


Leu Gly Thr 
145         


<210>  1082
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  1082

Met Gly Arg Pro Leu Leu Leu Pro Leu Leu Pro Leu Leu Leu Pro Pro 
1               5                   10                  15      


Ala Phe Leu Gln Pro Ser Gly Ser Thr Gly Ser Gly Pro Ser Tyr Leu 
            20                  25                  30          


Tyr Gly Val Thr Gln Pro Lys His Leu Ser Ala Ser Met Gly Gly Ser 
        35                  40                  45              


Val Glu Ile Pro Phe Ser Phe Tyr Tyr Pro Trp Glu Leu Ala Thr Ala 
    50                  55                  60                  


Pro Asp Val Arg Ile Ser Trp Arg Arg Gly His Phe His Gly Gln Ser 
65                  70                  75                  80  


Phe Tyr Ser Thr Arg Pro Pro Ser Ile His Lys Asp Tyr Val Asn Arg 
                85                  90                  95      


Leu Phe Leu Asn Trp Thr Glu Gly Gln Lys Ser Gly Phe Leu Arg Ile 
            100                 105                 110         


Ser Asn Leu Gln Lys Gln Asp Gln Ser Val Tyr Phe Cys Arg Val Glu 
        115                 120                 125             


Leu Asp Thr Arg Ser Ser Gly Arg Gln Gln Trp Gln Ser Ile Glu Gly 
    130                 135                 140                 


Thr Lys Leu Ser Ile Thr Gln Gly Gln Gln Arg Thr Lys Ala Thr Thr 
145                 150                 155                 160 


Pro Ala Arg Glu Pro Phe Gln Asn Thr Glu Glu Pro Tyr Glu Asn Ile 
                165                 170                 175     


Arg Asn Glu Gly Gln Asn Thr Asp Pro Lys Leu Asn Pro Lys Leu His 
            180                 185                 190         


Leu Thr Gln Ser Thr Ser Gln Pro Pro Ser Pro Gln Glu Pro Pro Glu 
        195                 200                 205             


Arg Asp Pro Val Leu Cys Leu Lys Gly Leu Thr Asn Gly Gln Pro Ser 
    210                 215                 220                 


Gln Asp 
225     


<210>  1083
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  1083

Gln Pro Gly Gly Ser Thr Gly Ser Gly Pro Ser Tyr Leu Tyr Gly Val 
1               5                   10                  15      


Thr Gln Pro Lys His Leu Ser Ala Ser Met Gly Gly Ser Val Glu Ile 
            20                  25                  30          


Pro Phe Ser Phe Tyr Tyr Pro Trp Glu Leu Ala Ile Val Pro Asn Val 
        35                  40                  45              


Arg Ile Ser Trp Arg Arg Gly His Phe His Gly Gln Ser Phe Tyr Ser 
    50                  55                  60                  


Thr Arg Pro Pro Ser Ile His Lys Asp Tyr Val Asn Arg Leu Phe Leu 
65                  70                  75                  80  


Asn Trp Thr Glu Gly Gln Glu Ser Gly Phe Leu Arg Ile Ser Asn Leu 
                85                  90                  95      


Arg Lys Glu Asp Gln Ser Val Tyr Phe Cys Arg Val Glu Leu Asp Thr 
            100                 105                 110         


Arg Arg Ser Gly Arg Gln Gln Leu Gln Ser Ile Lys Gly Thr Lys Leu 
        115                 120                 125             


Thr Ile Thr Gln Ala Val Thr Thr Thr Thr Thr Trp Arg Pro Ser Ser 
    130                 135                 140                 


Thr Thr Thr Ile Ala Gly Leu Arg Val Thr Glu Ser Lys Gly His Ser 
145                 150                 155                 160 


Glu Ser Trp His Leu Ser Leu Asp Thr Ala Ile Arg 
                165                 170         


<210>  1084
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  1084

Leu His Cys Glu Ile Cys Thr Ala Ala Gly Ser Arg Cys His Gly Gln 
1               5                   10                  15      


Met Lys Thr Cys Ser Ser Asp Lys Asp Thr Cys Val Leu Leu Val Gly 
            20                  25                  30          


Lys Ala Thr Ser Lys Gly Lys Glu Leu Val His Thr Tyr Lys Gly Cys 
        35                  40                  45              


Ile Arg Ser Gln Asp Cys Tyr Ser Gly Val Ile Ser Thr Thr Met Gly 
    50                  55                  60                  


Pro Lys Asp His Met Val Thr Ser Ser Phe Cys Cys Gln Ser Asp Gly 
65                  70                  75                  80  


Cys Asn Ser Ala Phe Leu Ser Val Pro Leu Thr Asn Leu Thr Glu Asn 
                85                  90                  95      


Gly Leu Met Cys Pro Ala Cys Thr Ala Ser Phe Arg Asp Lys Cys Met 
            100                 105                 110         


Gly Pro Met Thr His Cys Thr Gly Lys Glu Asn His Cys Val Ser Leu 
        115                 120                 125             


Ser Gly His Val Gln Ala Gly Ile Phe Lys Pro Arg Phe Ala Met Arg 
    130                 135                 140                 


Gly Cys Ala Thr Glu Ser Met Cys Phe Thr Lys Pro Gly Ala Glu Val 
145                 150                 155                 160 


Pro Thr Gly Thr Asn Val Leu Phe Leu His His Ile Glu Cys Thr His 
                165                 170                 175     


Ser Pro 
        


<210>  1085
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  1085

Gln Asp Asn Thr Arg Lys Ile Ile Ile Lys Asn Phe Asp Ile Pro Lys 
1               5                   10                  15      


Ser Val Arg Pro Asn Asp Glu Val Thr Ala Val Leu Ala Val Gln Thr 
            20                  25                  30          


Glu Leu Lys Glu Cys Met Val Val Lys Thr Tyr Leu Ile Ser Ser Ile 
        35                  40                  45              


Pro Leu Gln Gly Ala Phe Asn Tyr Lys Tyr Thr Ala Cys Leu Cys Asp 
    50                  55                  60                  


Asp Asn Pro Lys Thr Phe Tyr Trp Asp Phe Tyr Thr Asn Arg Thr Val 
65                  70                  75                  80  


Gln Ile Ala Ala Val Val Asp Val Ile Arg Glu Leu Gly Ile Cys Pro 
                85                  90                  95      


Asp Asp Ala Ala Val Ile Pro Ile Lys Asn Asn Arg Phe Tyr Thr Ile 
            100                 105                 110         


Glu Ile Leu Lys Val Glu 
        115             


<210>  1086
<211>  356
<212>  PRT
<213>  Homo Sapiens

<400>  1086

Val Ser Gly Ala Gln Tyr Met Gly Ser Gly Tyr Thr Lys Ala Val Tyr 
1               5                   10                  15      


Arg Val Arg Leu Pro Gly Gly Ala Ala Val Ala Leu Lys Ala Val Asp 
            20                  25                  30          


Phe Ser Gly His Asp Leu Gly Ser Cys Val Arg Glu Phe Gly Val Arg 
        35                  40                  45              


Arg Gly Cys Tyr Arg Leu Ala Ala His Lys Leu Leu Lys Glu Met Val 
    50                  55                  60                  


Leu Leu Glu Arg Leu Arg His Pro Asn Val Leu Gln Leu Tyr Gly Tyr 
65                  70                  75                  80  


Cys Tyr Gln Asp Ser Glu Asp Ile Pro Asp Thr Leu Thr Thr Ile Thr 
                85                  90                  95      


Glu Leu Gly Ala Pro Val Glu Met Ile Gln Leu Leu Gln Thr Ser Trp 
            100                 105                 110         


Glu Asp Arg Phe Arg Ile Cys Leu Ser Leu Gly Arg Leu Leu His His 
        115                 120                 125             


Leu Ala His Ser Pro Leu Gly Ser Val Thr Leu Leu Asp Phe Arg Pro 
    130                 135                 140                 


Arg Gln Phe Val Leu Val Asp Gly Glu Leu Lys Val Thr Asp Leu Asp 
145                 150                 155                 160 


Asp Ala Arg Val Glu Glu Thr Pro Cys Ala Gly Ser Thr Asp Cys Ile 
                165                 170                 175     


Leu Glu Phe Pro Ala Arg Asn Phe Thr Leu Pro Cys Ser Ala Gln Gly 
            180                 185                 190         


Trp Cys Glu Gly Met Asn Glu Lys Arg Asn Leu Tyr Asn Ala Tyr Arg 
        195                 200                 205             


Phe Phe Phe Thr Tyr Leu Leu Pro His Ser Ala Pro Pro Ser Leu Arg 
    210                 215                 220                 


Pro Leu Leu Asp Ser Ile Val Asn Ala Thr Gly Glu Leu Ala Trp Gly 
225                 230                 235                 240 


Val Asp Glu Thr Leu Ala Gln Leu Glu Lys Val Leu His Leu Tyr Arg 
                245                 250                 255     


Ser Gly Gln Tyr Leu Gln Asn Ser Thr Ala Ser Ser Ser Thr Glu Tyr 
            260                 265                 270         


Gln Cys Ile Pro Asp Ser Thr Ile Pro Gln Glu Asp Tyr Arg Cys Trp 
        275                 280                 285             


Pro Ser Tyr His His Gly Ser Cys Leu Leu Ser Val Phe Asn Leu Ala 
    290                 295                 300                 


Glu Ala Val Asp Val Cys Glu Ser His Ala Gln Cys Arg Ala Phe Val 
305                 310                 315                 320 


Val Thr Asn Gln Thr Thr Trp Thr Gly Arg Gln Leu Val Phe Phe Lys 
                325                 330                 335     


Thr Gly Trp Ser Gln Val Val Pro Asp Pro Asn Lys Thr Thr Tyr Val 
            340                 345                 350         


Lys Ala Ser Gly 
        355     


<210>  1087
<211>  527
<212>  PRT
<213>  Homo Sapiens

<400>  1087

Ser Tyr Gln Val Ile Cys Arg Asp Glu Lys Thr Gln Met Ile Tyr Gln 
1               5                   10                  15      


Gln His Gln Ser Trp Leu Arg Pro Val Leu Arg Ser Asn Arg Val Glu 
            20                  25                  30          


Tyr Cys Trp Cys Asn Ser Gly Arg Ala Gln Cys His Ser Val Pro Val 
        35                  40                  45              


Lys Ser Cys Ser Glu Pro Arg Cys Phe Asn Gly Gly Thr Cys Gln Gln 
    50                  55                  60                  


Ala Leu Tyr Phe Ser Asp Phe Val Cys Gln Cys Pro Glu Gly Phe Ala 
65                  70                  75                  80  


Gly Lys Cys Cys Glu Ile Asp Thr Arg Ala Thr Cys Tyr Glu Asp Gln 
                85                  90                  95      


Gly Ile Ser Tyr Arg Gly Thr Trp Ser Thr Ala Glu Ser Gly Ala Glu 
            100                 105                 110         


Cys Thr Asn Trp Asn Ser Ser Ala Leu Ala Gln Lys Pro Tyr Ser Gly 
        115                 120                 125             


Arg Arg Pro Asp Ala Ile Arg Leu Gly Leu Gly Asn His Asn Tyr Cys 
    130                 135                 140                 


Arg Asn Pro Asp Arg Asp Ser Lys Pro Trp Cys Tyr Val Phe Lys Ala 
145                 150                 155                 160 


Gly Lys Tyr Ser Ser Glu Phe Cys Ser Thr Pro Ala Cys Ser Glu Gly 
                165                 170                 175     


Asn Ser Asp Cys Tyr Phe Gly Asn Gly Ser Ala Tyr Arg Gly Thr His 
            180                 185                 190         


Ser Leu Thr Glu Ser Gly Ala Ser Cys Leu Pro Trp Asn Ser Met Ile 
        195                 200                 205             


Leu Ile Gly Lys Val Tyr Thr Ala Gln Asn Pro Ser Ala Gln Ala Leu 
    210                 215                 220                 


Gly Leu Gly Lys His Asn Tyr Cys Arg Asn Pro Asp Gly Asp Ala Lys 
225                 230                 235                 240 


Pro Trp Cys His Val Leu Lys Asn Arg Arg Leu Thr Trp Glu Tyr Cys 
                245                 250                 255     


Asp Val Pro Ser Cys Ser Thr Cys Gly Leu Arg Gln Tyr Ser Gln Pro 
            260                 265                 270         


Gln Phe Arg Ile Lys Gly Gly Leu Phe Ala Asp Ile Ala Ser His Pro 
        275                 280                 285             


Trp Gln Ala Ala Ile Phe Ala Lys His Arg Arg Ser Pro Gly Glu Arg 
    290                 295                 300                 


Phe Leu Cys Gly Gly Ile Leu Ile Ser Ser Cys Trp Ile Leu Ser Ala 
305                 310                 315                 320 


Ala His Cys Phe Gln Glu Arg Phe Pro Pro His His Leu Thr Val Ile 
                325                 330                 335     


Leu Gly Arg Thr Tyr Arg Val Val Pro Gly Glu Glu Glu Gln Lys Phe 
            340                 345                 350         


Glu Val Glu Lys Tyr Ile Val His Lys Glu Phe Asp Asp Asp Thr Tyr 
        355                 360                 365             


Asp Asn Asp Ile Ala Leu Leu Gln Leu Lys Ser Asp Ser Ser Arg Cys 
    370                 375                 380                 


Ala Gln Glu Ser Ser Val Val Arg Thr Val Cys Leu Pro Pro Ala Asp 
385                 390                 395                 400 


Leu Gln Leu Pro Asp Trp Thr Glu Cys Glu Leu Ser Gly Tyr Gly Lys 
                405                 410                 415     


His Glu Ala Leu Ser Pro Phe Tyr Ser Glu Arg Leu Lys Glu Ala His 
            420                 425                 430         


Val Arg Leu Tyr Pro Ser Ser Arg Cys Thr Ser Gln His Leu Leu Asn 
        435                 440                 445             


Arg Thr Val Thr Asp Asn Met Leu Cys Ala Gly Asp Thr Arg Ser Gly 
    450                 455                 460                 


Gly Pro Gln Ala Asn Leu His Asp Ala Cys Gln Gly Asp Ser Gly Gly 
465                 470                 475                 480 


Pro Leu Val Cys Leu Asn Asp Gly Arg Met Thr Leu Val Gly Ile Ile 
                485                 490                 495     


Ser Trp Gly Leu Gly Cys Gly Gln Lys Asp Val Pro Gly Val Tyr Thr 
            500                 505                 510         


Lys Val Thr Asn Tyr Leu Asp Trp Ile Arg Asp Asn Met Arg Pro 
        515                 520                 525         


<210>  1088
<211>  411
<212>  PRT
<213>  Homo Sapiens

<400>  1088

Ser Asn Glu Leu His Gln Val Pro Ser Asn Cys Asp Cys Leu Asn Gly 
1               5                   10                  15      


Gly Thr Cys Val Ser Asn Lys Tyr Phe Ser Asn Ile His Trp Cys Asn 
            20                  25                  30          


Cys Pro Lys Lys Phe Gly Gly Gln His Cys Glu Ile Asp Lys Ser Lys 
        35                  40                  45              


Thr Cys Tyr Glu Gly Asn Gly His Phe Tyr Arg Gly Lys Ala Ser Thr 
    50                  55                  60                  


Asp Thr Met Gly Arg Pro Cys Leu Pro Trp Asn Ser Ala Thr Val Leu 
65                  70                  75                  80  


Gln Gln Thr Tyr His Ala His Arg Ser Asp Ala Leu Gln Leu Gly Leu 
                85                  90                  95      


Gly Lys His Asn Tyr Cys Arg Asn Pro Asp Asn Arg Arg Arg Pro Trp 
            100                 105                 110         


Cys Tyr Val Gln Val Gly Leu Lys Pro Leu Val Gln Glu Cys Met Val 
        115                 120                 125             


His Asp Cys Ala Asp Gly Lys Lys Pro Ser Ser Pro Pro Glu Glu Leu 
    130                 135                 140                 


Lys Phe Gln Cys Gly Gln Lys Thr Leu Arg Pro Arg Phe Lys Ile Ile 
145                 150                 155                 160 


Gly Gly Glu Phe Thr Thr Ile Glu Asn Gln Pro Trp Phe Ala Ala Ile 
                165                 170                 175     


Tyr Arg Arg His Arg Gly Gly Ser Val Thr Tyr Val Cys Gly Gly Ser 
            180                 185                 190         


Leu Ile Ser Pro Cys Trp Val Ile Ser Ala Thr His Cys Phe Ile Asp 
        195                 200                 205             


Tyr Pro Lys Lys Glu Asp Tyr Ile Val Tyr Leu Gly Arg Ser Arg Leu 
    210                 215                 220                 


Asn Ser Asn Thr Gln Gly Glu Met Lys Phe Glu Val Glu Asn Leu Ile 
225                 230                 235                 240 


Leu His Lys Asp Tyr Ser Ala Asp Thr Leu Ala His His Asn Asp Ile 
                245                 250                 255     


Ala Leu Leu Lys Ile Arg Ser Lys Glu Gly Arg Cys Ala Gln Pro Ser 
            260                 265                 270         


Arg Thr Ile Gln Thr Ile Cys Leu Pro Ser Met Tyr Asn Asp Pro Gln 
        275                 280                 285             


Phe Gly Thr Ser Cys Glu Ile Thr Gly Phe Gly Lys Glu Asn Ser Thr 
    290                 295                 300                 


Asp Tyr Leu Tyr Pro Glu Gln Leu Lys Met Thr Val Val Lys Leu Ile 
305                 310                 315                 320 


Ser His Arg Glu Cys Gln Gln Pro His Tyr Tyr Gly Ser Glu Val Thr 
                325                 330                 335     


Thr Lys Met Leu Cys Ala Ala Asp Pro Gln Trp Lys Thr Asp Ser Cys 
            340                 345                 350         


Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Ser Leu Gln Gly Arg Met 
        355                 360                 365             


Thr Leu Thr Gly Ile Val Ser Trp Gly Arg Gly Cys Ala Leu Lys Asp 
    370                 375                 380                 


Lys Pro Gly Val Tyr Thr Arg Val Ser His Phe Leu Pro Trp Ile Arg 
385                 390                 395                 400 


Ser His Thr Lys Glu Glu Asn Gly Leu Ala Leu 
                405                 410     


<210>  1089
<211>  283
<212>  PRT
<213>  Homo Sapiens

<400>  1089

Leu Arg Cys Met Gln Cys Lys Thr Asn Gly Asp Cys Arg Val Glu Glu 
1               5                   10                  15      


Cys Ala Leu Gly Gln Asp Leu Cys Arg Thr Thr Ile Val Arg Leu Trp 
            20                  25                  30          


Glu Glu Gly Glu Glu Leu Glu Leu Val Glu Lys Ser Cys Thr His Ser 
        35                  40                  45              


Glu Lys Thr Asn Arg Thr Leu Ser Tyr Arg Thr Gly Leu Lys Ile Thr 
    50                  55                  60                  


Ser Leu Thr Glu Val Val Cys Gly Leu Asp Leu Cys Asn Gln Gly Asn 
65                  70                  75                  80  


Ser Gly Arg Ala Val Thr Tyr Ser Arg Ser Arg Tyr Leu Glu Cys Ile 
                85                  90                  95      


Ser Cys Gly Ser Ser Asp Met Ser Cys Glu Arg Gly Arg His Gln Ser 
            100                 105                 110         


Leu Gln Cys Arg Ser Pro Glu Glu Gln Cys Leu Asp Val Val Thr His 
        115                 120                 125             


Trp Ile Gln Glu Gly Glu Glu Gly Arg Pro Lys Asp Asp Arg His Leu 
    130                 135                 140                 


Arg Gly Cys Gly Tyr Leu Pro Gly Cys Pro Gly Ser Asn Gly Phe His 
145                 150                 155                 160 


Asn Asn Asp Thr Phe His Phe Leu Lys Cys Cys Asn Thr Thr Lys Cys 
                165                 170                 175     


Asn Glu Gly Pro Ile Leu Glu Leu Glu Asn Leu Pro Gln Asn Gly Arg 
            180                 185                 190         


Gln Cys Tyr Ser Cys Lys Gly Asn Ser Thr His Gly Cys Ser Ser Glu 
        195                 200                 205             


Glu Thr Phe Leu Ile Asp Cys Arg Gly Pro Met Asn Gln Cys Leu Val 
    210                 215                 220                 


Ala Thr Gly Thr His Glu Pro Lys Asn Gln Ser Tyr Met Val Arg Gly 
225                 230                 235                 240 


Cys Ala Thr Ala Ser Met Cys Gln His Ala His Leu Gly Asp Ala Phe 
                245                 250                 255     


Ser Met Asn His Ile Asp Val Ser Cys Cys Thr Lys Ser Gly Cys Asn 
            260                 265                 270         


His Pro Asp Leu Asp Val Gln Tyr Arg Ser Gly 
        275                 280             


<210>  1090
<211>  499
<212>  PRT
<213>  Homo Sapiens

<400>  1090

Thr Leu Leu Thr Arg Gln Pro Ala Pro Leu Ser Gln Lys Gln Arg Ser 
1               5                   10                  15      


Phe Val Thr Phe Arg Gly Glu Pro Ala Glu Gly Phe Asn His Leu Val 
            20                  25                  30          


Val Asp Glu Arg Thr Gly His Ile Tyr Leu Gly Ala Val Asn Arg Ile 
        35                  40                  45              


Tyr Lys Leu Ser Ser Asp Leu Lys Val Leu Val Thr His Glu Thr Gly 
    50                  55                  60                  


Pro Asp Glu Asp Asn Pro Lys Cys Tyr Pro Pro Arg Ile Val Gln Thr 
65                  70                  75                  80  


Cys Asn Glu Pro Leu Thr Thr Thr Asn Asn Val Asn Lys Met Leu Leu 
                85                  90                  95      


Ile Asp Tyr Lys Glu Asn Arg Leu Ile Ala Cys Gly Ser Leu Tyr Gln 
            100                 105                 110         


Gly Ile Cys Lys Leu Leu Arg Leu Glu Asp Leu Phe Lys Leu Gly Glu 
        115                 120                 125             


Pro Tyr His Lys Lys Glu His Tyr Leu Ser Gly Val Asn Glu Ser Gly 
    130                 135                 140                 


Ser Val Phe Gly Val Ile Val Ser Tyr Ser Asn Leu Asp Asp Lys Leu 
145                 150                 155                 160 


Phe Ile Ala Thr Ala Val Asp Gly Lys Pro Glu Tyr Phe Pro Thr Ile 
                165                 170                 175     


Ser Ser Arg Lys Leu Thr Lys Asn Ser Glu Ala Asp Gly Met Phe Ala 
            180                 185                 190         


Tyr Val Phe His Asp Glu Phe Val Ala Ser Met Ile Lys Ile Pro Ser 
        195                 200                 205             


Asp Thr Phe Thr Ile Ile Pro Asp Phe Asp Ile Tyr Tyr Val Tyr Gly 
    210                 215                 220                 


Phe Ser Ser Gly Asn Phe Val Tyr Phe Leu Thr Leu Gln Pro Glu Met 
225                 230                 235                 240 


Val Ser Pro Pro Gly Ser Thr Thr Lys Glu Gln Val Tyr Thr Ser Lys 
                245                 250                 255     


Leu Val Arg Leu Cys Lys Glu Asp Thr Ala Phe Asn Ser Tyr Val Glu 
            260                 265                 270         


Val Pro Ile Gly Cys Glu Arg Ser Gly Val Glu Tyr Arg Leu Leu Gln 
        275                 280                 285             


Ala Ala Tyr Leu Ser Lys Ala Gly Ala Val Leu Gly Arg Thr Leu Gly 
    290                 295                 300                 


Val His Pro Asp Asp Asp Leu Leu Phe Thr Val Phe Ser Lys Gly Gln 
305                 310                 315                 320 


Lys Arg Lys Met Lys Ser Leu Asp Glu Ser Ala Leu Cys Ile Phe Ile 
                325                 330                 335     


Leu Lys Gln Ile Asn Asp Arg Ile Lys Glu Arg Leu Gln Ser Cys Tyr 
            340                 345                 350         


Arg Gly Glu Gly Thr Leu Asp Leu Ala Trp Leu Lys Val Lys Asp Ile 
        355                 360                 365             


Pro Cys Ser Ser Ala Leu Leu Thr Ile Asp Asp Asn Phe Cys Gly Leu 
    370                 375                 380                 


Asp Met Asn Ala Pro Leu Gly Val Ser Asp Met Val Arg Gly Ile Pro 
385                 390                 395                 400 


Val Phe Thr Glu Asp Arg Asp Arg Met Thr Ser Val Ile Ala Tyr Val 
                405                 410                 415     


Tyr Lys Asn His Ser Leu Ala Phe Val Gly Thr Lys Ser Gly Lys Leu 
            420                 425                 430         


Lys Lys Ser Phe Gly Thr Gly Pro Gln Gly Gly Ile Thr Gln Glu Trp 
        435                 440                 445             


Ile Gly Val Ala Gly Asp Pro Pro Gly Ala Asn Ile Ala Ser Gln Glu 
    450                 455                 460                 


Gln Met Leu Cys Val Tyr Leu Gln Cys Ser Ser His Lys Ala Ile Ser 
465                 470                 475                 480 


Asp Gln Arg Val Gln Pro Leu Leu Cys Cys Phe Leu Asn Val Pro Gly 
                485                 490                 495     


Asn Ser Ser 
            


<210>  1091
<211>  594
<212>  PRT
<213>  Homo Sapiens

<400>  1091

Gly Pro Val Leu Ala Val Arg Ala Pro Gly Phe Gly Arg Ser Gly Gly 
1               5                   10                  15      


His Ser Leu Ser Pro Glu Glu Asn Glu Phe Ala Glu Glu Glu Pro Val 
            20                  25                  30          


Leu Val Leu Ser Pro Glu Glu Pro Gly Pro Gly Pro Ala Ala Val Ser 
        35                  40                  45              


Cys Pro Arg Asp Cys Ala Cys Ser Gln Glu Gly Val Val Asp Cys Gly 
    50                  55                  60                  


Gly Ile Asp Leu Arg Glu Phe Pro Gly Asp Leu Pro Glu His Thr Asn 
65                  70                  75                  80  


His Leu Ser Leu Gln Asn Asn Gln Leu Glu Lys Ile Tyr Pro Glu Glu 
                85                  90                  95      


Leu Ser Arg Leu His Arg Leu Glu Thr Leu Asn Leu Gln Asn Asn Arg 
            100                 105                 110         


Leu Thr Ser Arg Gly Leu Pro Glu Lys Ala Phe Glu His Leu Thr Asn 
        115                 120                 125             


Leu Asn Tyr Leu Tyr Leu Ala Asn Asn Lys Leu Thr Leu Ala Pro Arg 
    130                 135                 140                 


Phe Leu Pro Asn Ala Leu Ile Ser Val Asp Phe Ala Ala Asn Tyr Leu 
145                 150                 155                 160 


Thr Lys Ile Tyr Gly Leu Thr Phe Gly Gln Lys Pro Asn Leu Arg Ser 
                165                 170                 175     


Val Tyr Leu His Asn Asn Lys Leu Ala Asp Ala Gly Leu Pro Asp Asn 
            180                 185                 190         


Met Phe Asn Gly Ser Ser Asn Val Glu Val Leu Ile Leu Ser Ser Asn 
        195                 200                 205             


Phe Leu Arg His Val Pro Lys His Leu Pro Pro Ala Leu Tyr Lys Leu 
    210                 215                 220                 


His Leu Lys Asn Asn Lys Leu Glu Lys Ile Pro Pro Gly Ala Phe Ser 
225                 230                 235                 240 


Glu Leu Ser Ser Leu Arg Glu Leu Tyr Leu Gln Asn Asn Tyr Leu Thr 
                245                 250                 255     


Asp Glu Gly Leu Asp Asn Glu Thr Phe Trp Lys Leu Ser Ser Leu Glu 
            260                 265                 270         


Tyr Leu Asp Leu Ser Ser Asn Asn Leu Ser Arg Val Pro Ala Gly Leu 
        275                 280                 285             


Pro Arg Ser Leu Val Leu Leu His Leu Glu Lys Asn Ala Ile Arg Ser 
    290                 295                 300                 


Val Asp Ala Asn Val Leu Thr Pro Ile Arg Ser Leu Glu Tyr Leu Leu 
305                 310                 315                 320 


Leu His Ser Asn Gln Leu Arg Glu Gln Gly Ile His Pro Leu Ala Phe 
                325                 330                 335     


Gln Gly Leu Lys Arg Leu His Thr Val His Leu Tyr Asn Asn Ala Leu 
            340                 345                 350         


Glu Arg Val Pro Ser Gly Leu Pro Arg Arg Val Arg Thr Leu Met Ile 
        355                 360                 365             


Leu His Asn Gln Ile Thr Gly Ile Gly Arg Glu Asp Phe Ala Thr Thr 
    370                 375                 380                 


Tyr Phe Leu Glu Glu Leu Asn Leu Ser Tyr Asn Arg Ile Thr Ser Pro 
385                 390                 395                 400 


Gln Val His Arg Asp Ala Phe Arg Lys Leu Arg Leu Leu Arg Ser Leu 
                405                 410                 415     


Asp Leu Ser Gly Asn Arg Leu His Thr Leu Pro Pro Gly Leu Pro Arg 
            420                 425                 430         


Asn Val His Val Leu Lys Val Lys Arg Asn Glu Leu Ala Ala Leu Ala 
        435                 440                 445             


Arg Gly Ala Leu Ala Gly Met Ala Gln Leu Arg Glu Leu Tyr Leu Thr 
    450                 455                 460                 


Ser Asn Arg Leu Arg Ser Arg Ala Leu Gly Pro Arg Ala Trp Val Asp 
465                 470                 475                 480 


Leu Ala His Leu Gln Leu Leu Asp Ile Ala Gly Asn Gln Leu Thr Glu 
                485                 490                 495     


Ile Pro Glu Gly Leu Pro Glu Ser Leu Glu Tyr Leu Tyr Leu Gln Asn 
            500                 505                 510         


Asn Lys Ile Ser Ala Val Pro Ala Asn Ala Phe Asp Ser Thr Pro Asn 
        515                 520                 525             


Leu Lys Gly Ile Phe Leu Arg Phe Asn Lys Leu Ala Val Gly Ser Val 
    530                 535                 540                 


Val Asp Ser Ala Phe Arg Arg Leu Lys His Leu Gln Val Leu Asp Ile 
545                 550                 555                 560 


Glu Gly Asn Leu Glu Phe Gly Asp Ile Ser Lys Asp Arg Gly Arg Leu 
                565                 570                 575     


Gly Lys Glu Lys Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu 
            580                 585                 590         


Thr Arg 
        


<210>  1092
<211>  486
<212>  PRT
<213>  Homo Sapiens

<400>  1092

Leu Glu Asp Ala Ala Phe Pro His Leu Gly Glu Ser Leu Gln Pro Leu 
1               5                   10                  15      


Leu Arg Ala Cys Pro Leu Arg Cys Ser Cys Pro Arg Val Asp Thr Val 
            20                  25                  30          


Asp Cys Asp Gly Leu Asp Leu Arg Val Phe Pro Asp Asn Ile Thr Arg 
        35                  40                  45              


Ala Ala Gln His Leu Ser Leu Gln Asn Asn Gln Leu Gln Glu Leu Pro 
    50                  55                  60                  


Tyr Asn Glu Leu Ser Arg Leu Ser Gly Leu Arg Thr Leu Asn Leu His 
65                  70                  75                  80  


Asn Asn Leu Ile Ser Ser Glu Gly Leu Pro Asp Glu Ala Phe Glu Ser 
                85                  90                  95      


Leu Thr Gln Leu Gln His Leu Cys Val Ala His Asn Lys Leu Ser Val 
            100                 105                 110         


Ala Pro Gln Phe Leu Pro Arg Ser Leu Arg Val Ala Asp Leu Ala Ala 
        115                 120                 125             


Asn Gln Val Met Glu Ile Phe Pro Leu Thr Phe Gly Glu Lys Pro Ala 
    130                 135                 140                 


Leu Arg Ser Val Tyr Leu His Asn Asn Gln Leu Ser Asn Ala Gly Leu 
145                 150                 155                 160 


Pro Pro Asp Ala Phe Arg Gly Ser Glu Ala Ile Ala Thr Leu Ser Leu 
                165                 170                 175     


Ser Asn Asn Gln Leu Ser Tyr Leu Pro Pro Ser Leu Pro Pro Ser Leu 
            180                 185                 190         


Glu Arg Leu His Leu Gln Asn Asn Leu Ile Ser Lys Val Pro Arg Gly 
        195                 200                 205             


Ala Leu Ser Arg Gln Thr Gln Leu Arg Glu Leu Tyr Leu Gln His Asn 
    210                 215                 220                 


Gln Leu Thr Asp Ser Gly Leu Asp Ala Thr Thr Phe Ser Lys Leu His 
225                 230                 235                 240 


Ser Leu Glu Tyr Leu Asp Leu Ser His Asn Gln Leu Thr Thr Val Pro 
                245                 250                 255     


Ala Gly Leu Pro Arg Thr Leu Ala Ile Leu His Leu Gly Arg Asn Arg 
            260                 265                 270         


Ile Arg Gln Val Glu Ala Ala Arg Leu His Gly Ala Arg Gly Leu Arg 
        275                 280                 285             


Tyr Leu Leu Leu Gln His Asn Gln Leu Gly Ser Ser Gly Leu Pro Ala 
    290                 295                 300                 


Gly Ala Leu Arg Pro Leu Arg Gly Leu His Thr Leu His Leu Tyr Gly 
305                 310                 315                 320 


Asn Gly Leu Asp Arg Val Pro Pro Ala Leu Pro Arg Arg Leu Arg Ala 
                325                 330                 335     


Leu Val Leu Pro His Asn His Val Ala Ala Leu Gly Ala Arg Asp Leu 
            340                 345                 350         


Val Ala Thr Pro Gly Leu Thr Glu Leu Asn Leu Ala Tyr Asn Arg Leu 
        355                 360                 365             


Ala Ser Ala Arg Val His His Arg Ala Phe Arg Arg Leu Arg Ala Leu 
    370                 375                 380                 


Arg Ser Leu Asp Leu Ala Gly Asn Gln Leu Thr Arg Leu Pro Met Gly 
385                 390                 395                 400 


Leu Pro Thr Gly Leu Arg Thr Leu Gln Leu Gln Arg Asn Gln Leu Arg 
                405                 410                 415     


Met Leu Glu Pro Glu Pro Leu Ala Gly Leu Asp Gln Leu Arg Glu Leu 
            420                 425                 430         


Ser Leu Ala His Asn Arg Leu Arg Val Gly Asp Ile Gly Pro Gly Thr 
        435                 440                 445             


Trp His Glu Leu Gln Ala Leu Gln Val Arg His Arg Leu Val Ser His 
    450                 455                 460                 


Thr Val Pro Arg Ala Pro Pro Ser Pro Cys Leu Pro Cys His Val Pro 
465                 470                 475                 480 


Asn Ile Leu Val Ser Trp 
                485     


<210>  1093
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  1093

Ala Glu Leu Arg Cys Met Cys Ile Lys Thr Thr Ser Gly Ile His Pro 
1               5                   10                  15      


Lys Asn Ile Gln Ser Leu Glu Val Ile Gly Lys Gly Thr His Cys Asn 
            20                  25                  30          


Gln Val Glu Val Ile Ala Thr Leu Lys Asp Gly Arg Lys Ile Cys Leu 
        35                  40                  45              


Asp Pro Asp Ala Pro Arg Ile Lys Lys Ile Val Gln Lys Lys Leu Ala 
    50                  55                  60                  


Gly Asp Glu Ser Ala Asp 
65                  70  


<210>  1094
<211>  268
<212>  PRT
<213>  Homo Sapiens

<400>  1094

Ala Lys Gly Gly Ser Leu Arg Glu Ser Gln Gly Val Cys Ser Lys Gln 
1               5                   10                  15      


Thr Leu Val Val Pro Leu His Tyr Asn Glu Ser Tyr Ser Gln Pro Val 
            20                  25                  30          


Tyr Lys Pro Tyr Leu Thr Leu Cys Ala Gly Arg Arg Ile Cys Ser Thr 
        35                  40                  45              


Tyr Arg Thr Met Tyr Arg Val Met Trp Arg Glu Val Arg Arg Glu Val 
    50                  55                  60                  


Gln Gln Thr His Ala Val Cys Cys Gln Gly Trp Lys Lys Arg His Pro 
65                  70                  75                  80  


Gly Ala Leu Thr Cys Glu Ala Ile Cys Ala Lys Pro Cys Leu Asn Gly 
                85                  90                  95      


Gly Val Cys Val Arg Pro Asp Gln Cys Glu Cys Ala Pro Gly Trp Gly 
            100                 105                 110         


Gly Lys His Cys His Val Asp Val Asp Glu Cys Arg Thr Ser Ile Thr 
        115                 120                 125             


Leu Cys Ser His His Cys Phe Asn Thr Ala Gly Ser Phe Thr Cys Gly 
    130                 135                 140                 


Cys Pro His Asp Leu Val Leu Gly Val Asp Gly Arg Thr Cys Met Glu 
145                 150                 155                 160 


Gly Ser Pro Glu Pro Pro Thr Ser Ala Ser Ile Leu Ser Val Ala Val 
                165                 170                 175     


Arg Glu Ala Glu Lys Asp Glu Arg Ala Leu Lys Gln Glu Ile His Glu 
            180                 185                 190         


Leu Arg Gly Arg Leu Glu Arg Leu Glu Gln Trp Ala Gly Gln Ala Gly 
        195                 200                 205             


Ala Trp Val Arg Ala Val Leu Pro Val Pro Pro Glu Glu Leu Gln Pro 
    210                 215                 220                 


Glu Gln Val Ala Glu Leu Trp Gly Arg Gly Asp Arg Ile Glu Ser Leu 
225                 230                 235                 240 


Ser Asp Gln Val Leu Leu Leu Glu Glu Arg Leu Gly Ala Cys Ser Cys 
                245                 250                 255     


Glu Asp Asn Ser Leu Gly Leu Gly Val Asn His Arg 
            260                 265             


<210>  1095
<211>  362
<212>  PRT
<213>  Homo Sapiens

<400>  1095

Gln Pro Thr Arg Arg Pro Arg Pro Gly Thr Gly Pro Gly Arg Arg Pro 
1               5                   10                  15      


Arg Pro Arg Pro Arg Pro Thr Pro Ser Phe Pro Gln Pro Asp Glu Pro 
            20                  25                  30          


Ala Glu Pro Thr Asp Leu Pro Pro Pro Leu Pro Pro Gly Pro Pro Ser 
        35                  40                  45              


Ile Phe Pro Asp Cys Pro Arg Glu Cys Tyr Cys Pro Pro Asp Phe Pro 
    50                  55                  60                  


Ser Ala Leu Tyr Cys Asp Ser Arg Asn Leu Arg Lys Val Pro Val Ile 
65                  70                  75                  80  


Pro Pro Arg Ile His Tyr Leu Tyr Leu Gln Asn Asn Phe Ile Thr Glu 
                85                  90                  95      


Leu Pro Val Glu Ser Phe Gln Asn Ala Thr Gly Leu Arg Trp Ile Asn 
            100                 105                 110         


Leu Asp Asn Asn Arg Ile Arg Lys Ile Asp Gln Arg Val Leu Glu Lys 
        115                 120                 125             


Leu Pro Gly Leu Val Phe Leu Tyr Met Glu Lys Asn Gln Leu Glu Glu 
    130                 135                 140                 


Val Pro Ser Ala Leu Pro Arg Asn Leu Glu Gln Leu Arg Leu Ser Gln 
145                 150                 155                 160 


Asn His Ile Ser Arg Ile Pro Pro Gly Val Phe Ser Lys Leu Glu Asn 
                165                 170                 175     


Leu Leu Leu Leu Asp Leu Gln His Asn Arg Leu Ser Asp Gly Val Phe 
            180                 185                 190         


Lys Pro Asp Thr Phe His Gly Leu Lys Asn Leu Met Gln Leu Asn Leu 
        195                 200                 205             


Ala His Asn Ile Leu Arg Lys Met Pro Pro Arg Val Pro Thr Ala Ile 
    210                 215                 220                 


His Gln Leu Tyr Leu Asp Ser Asn Lys Ile Glu Thr Ile Pro Asn Gly 
225                 230                 235                 240 


Tyr Phe Lys Ser Phe Pro Asn Leu Ala Phe Ile Arg Leu Asn Tyr Asn 
                245                 250                 255     


Lys Leu Thr Asp Arg Gly Leu Pro Lys Asn Ser Phe Asn Ile Ser Asn 
            260                 265                 270         


Leu Leu Val Leu His Leu Ser His Asn Arg Ile Ser Ser Val Pro Ala 
        275                 280                 285             


Ile Asn Asn Arg Leu Glu His Leu Tyr Leu Asn Asn Asn Ser Ile Glu 
    290                 295                 300                 


Lys Ile Asn Gly Thr Gln Ile Cys Pro Asn Asp Leu Val Ala Phe His 
305                 310                 315                 320 


Asp Phe Ser Ser Asp Leu Glu Asn Val Pro His Leu Arg Tyr Leu Arg 
                325                 330                 335     


Leu Asp Gly Asn Tyr Leu Lys Pro Pro Ile Pro Leu Asp Leu Met Met 
            340                 345                 350         


Cys Phe Arg Leu Leu Gln Ser Val Val Ile 
        355                 360         


<210>  1096
<211>  534
<212>  PRT
<213>  Homo Sapiens

<400>  1096

Pro Cys His Thr Ala Ala Arg Ser Glu Cys Lys Arg Ser His Lys Phe 
1               5                   10                  15      


Val Pro Gly Ala Trp Leu Ala Gly Glu Gly Val Asp Val Thr Ser Leu 
            20                  25                  30          


Arg Arg Ser Gly Ser Phe Pro Val Asp Thr Gln Arg Phe Leu Arg Pro 
        35                  40                  45              


Asp Gly Thr Cys Thr Leu Cys Glu Asn Ala Leu Gln Glu Gly Thr Leu 
    50                  55                  60                  


Gln Arg Leu Pro Leu Ala Leu Thr Asn Trp Arg Ala Gln Gly Ser Gly 
65                  70                  75                  80  


Cys Gln Arg His Val Thr Arg Ala Lys Val Ser Ser Thr Glu Ala Val 
                85                  90                  95      


Ala Arg Asp Ala Ala Arg Ser Ile Arg Asn Asp Trp Lys Val Gly Leu 
            100                 105                 110         


Asp Val Thr Pro Lys Pro Thr Ser Asn Val His Val Ser Val Ala Gly 
        115                 120                 125             


Ser His Ser Gln Ala Ala Asn Phe Ala Ala Gln Lys Thr His Gln Asp 
    130                 135                 140                 


Gln Tyr Ser Phe Ser Thr Asp Thr Val Glu Cys Arg Phe Tyr Ser Phe 
145                 150                 155                 160 


His Val Val His Thr Pro Pro Leu His Pro Asp Phe Lys Arg Ala Leu 
                165                 170                 175     


Gly Asp Leu Pro His His Phe Asn Ala Ser Thr Gln Pro Ala Tyr Leu 
            180                 185                 190         


Arg Leu Ile Ser Asn Tyr Gly Thr His Phe Ile Arg Ala Val Glu Leu 
        195                 200                 205             


Gly Gly Arg Ile Ser Ala Leu Thr Ala Leu Arg Thr Cys Glu Leu Ala 
    210                 215                 220                 


Leu Glu Gly Leu Thr Asp Asn Glu Val Glu Asp Cys Leu Thr Val Glu 
225                 230                 235                 240 


Ala Gln Val Asn Ile Gly Ile His Gly Ser Ile Ser Ala Glu Ala Lys 
                245                 250                 255     


Ala Cys Glu Glu Lys Lys Lys Lys His Lys Met Thr Ala Ser Phe His 
            260                 265                 270         


Gln Thr Tyr Arg Glu Arg His Ser Glu Val Val Gly Gly His His Thr 
        275                 280                 285             


Ser Ile Asn Asp Leu Leu Phe Gly Ile Gln Ala Gly Pro Glu Gln Tyr 
    290                 295                 300                 


Ser Ala Trp Val Asn Ser Leu Pro Gly Ser Pro Gly Leu Val Asp Tyr 
305                 310                 315                 320 


Thr Leu Glu Pro Leu His Val Leu Leu Asp Ser Gln Asp Pro Arg Arg 
                325                 330                 335     


Glu Ala Leu Arg Arg Ala Leu Ser Gln Tyr Leu Thr Asp Arg Ala Arg 
            340                 345                 350         


Trp Arg Asp Cys Ser Arg Pro Cys Pro Pro Gly Arg Gln Lys Ser Pro 
        355                 360                 365             


Arg Asp Pro Cys Gln Cys Val Cys His Gly Ser Ala Val Thr Thr Gln 
    370                 375                 380                 


Asp Cys Cys Pro Arg Gln Arg Gly Leu Ala Gln Leu Glu Val Thr Phe 
385                 390                 395                 400 


Ile Gln Ala Trp Gly Leu Trp Gly Asp Trp Phe Thr Ala Thr Asp Ala 
                405                 410                 415     


Tyr Val Lys Leu Phe Phe Gly Gly Gln Glu Leu Arg Thr Ser Thr Val 
            420                 425                 430         


Trp Asp Asn Asn Asn Pro Ile Trp Ser Val Arg Leu Asp Phe Gly Asp 
        435                 440                 445             


Val Leu Leu Ala Thr Gly Gly Pro Leu Arg Leu Gln Val Trp Asp Gln 
    450                 455                 460                 


Asp Ser Gly Arg Asp Asp Asp Leu Leu Gly Thr Cys Asp Gln Ala Pro 
465                 470                 475                 480 


Lys Ser Gly Ser His Glu Val Arg Cys Asn Leu Asn His Gly His Leu 
                485                 490                 495     


Lys Phe Arg Tyr His Ala Arg Cys Leu Pro His Leu Gly Gly Gly Thr 
            500                 505                 510         


Cys Leu Asp Tyr Val Pro Gln Met Leu Leu Gly Glu Pro Pro Gly Asn 
        515                 520                 525             


Arg Ser Gly Ala Val Trp 
    530                 


<210>  1097
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  1097

Thr Cys Arg Tyr Leu Leu Val Arg Ser Leu Gln Thr Phe Ser Gln Ala 
1               5                   10                  15      


Trp Phe Thr Cys Arg Arg Cys Tyr Arg Gly Asn Leu Val Ser Ile His 
            20                  25                  30          


Asn Phe Asn Ile Asn Tyr Arg Ile Gln Cys Ser Val Ser Ala Leu Asn 
        35                  40                  45              


Gln Gly Gln Val Trp Ile Gly Gly Arg Ile Thr Gly Ser Gly Arg Cys 
    50                  55                  60                  


Arg Arg Phe Gln Trp Val Asp Gly Ser Arg Trp Asn Phe Ala Tyr Trp 
65                  70                  75                  80  


Ala Ala His Gln Pro Trp Ser Arg Gly Gly His Cys Val Ala Leu Cys 
                85                  90                  95      


Thr Arg Gly Gly Tyr Trp Arg Arg Ala His Cys Leu Arg Arg Leu Pro 
            100                 105                 110         


Phe Ile Cys Ser Tyr 
        115         


<210>  1098
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  1098

Leu His Leu Glu Asn Asp Ala Pro His Leu Glu Ser Leu Glu Thr Gln 
1               5                   10                  15      


Ala Asp Leu Gly Gln Asp Leu Asp Ser Ser Lys Glu Gln Glu Arg Asp 
            20                  25                  30          


Leu Ala Leu Thr Glu Glu Val Ile Gln Ala Glu Gly Glu Glu Val Lys 
        35                  40                  45              


Ala Ser Ala Cys Gln Asp Asn Phe Glu Asp Glu Glu Ala Met Glu Ser 
    50                  55                  60                  


Asp Pro Ala Ala Leu Asp Lys Asp Phe Gln Cys Pro Arg Glu Glu Asp 
65                  70                  75                  80  


Ile Val Glu Val Gln Gly Ser Pro Arg Cys Lys Thr Cys Arg Tyr Leu 
                85                  90                  95      


Leu Val Arg Thr Pro Lys Thr Phe Ala Glu Ala Gln Asn Val Cys Ser 
            100                 105                 110         


Arg Cys Tyr Gly Gly Asn Leu Val Ser Ile His Asp Phe Asn Phe Asn 
        115                 120                 125             


Tyr Arg Ile Gln Cys Cys Thr Ser Thr Val Asn Gln Ala Gln Val Trp 
    130                 135                 140                 


Ile Gly Gly Asn Leu Arg Gly Trp Phe Leu Trp Lys Arg Phe Cys Trp 
145                 150                 155                 160 


Thr Asp Gly Ser His Trp Asn Phe Ala Tyr Trp Ser Pro Gly Gln Pro 
                165                 170                 175     


Gly Asn Gly Gln Gly Ser Cys Val Ala Leu Cys Thr Lys Gly Gly Tyr 
            180                 185                 190         


Trp Arg Arg Ala Gln Cys Asp Lys Gln Leu Pro Phe Val Cys Ser Phe 
        195                 200                 205             


<210>  1099
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  1099

Gln Leu Pro Pro Gly Lys Pro Glu Ile Phe Lys Cys Arg Ser Pro Asn 
1               5                   10                  15      


Lys Glu Thr Phe Thr Cys Trp Trp Arg Pro Gly Thr Asp Gly Gly Leu 
            20                  25                  30          


Pro Thr Asn Tyr Ser Leu Thr Tyr His Arg Glu Gly Glu Thr Leu Met 
        35                  40                  45              


His Glu Cys Pro Asp Tyr Ile Thr Gly Gly Pro Asn Ser Cys His Phe 
    50                  55                  60                  


Gly Lys Gln Tyr Thr Ser Met Trp Arg Thr Tyr Ile Met Met Val Asn 
65                  70                  75                  80  


Ala Thr Asn Gln Met Gly Ser Ser Phe Ser Asp Glu Leu Tyr Val Asp 
                85                  90                  95      


Val Thr Tyr Ile Val Gln Pro Asp Pro Pro Leu Glu Leu Ala Val Glu 
            100                 105                 110         


Val Lys Gln Pro Glu Asp Arg Lys Pro Tyr Leu Trp Ile Lys Trp Ser 
        115                 120                 125             


Pro Pro Thr Leu Ile Asp Leu Lys Thr Gly Trp Phe Thr Leu Leu Tyr 
    130                 135                 140                 


Glu Ile Arg Leu Lys Pro Glu Lys Ala Ala Glu Trp Glu Ile His Phe 
145                 150                 155                 160 


Ala Gly Gln Gln Thr Glu Phe Lys Ile Leu Ser Leu His Pro Gly Gln 
                165                 170                 175     


Lys Tyr Leu Val Gln Val Arg Cys Lys Pro Asp His Gly Tyr Trp Ser 
            180                 185                 190         


Ala Trp Ser Pro Ala Thr Phe Ile Gln Ile Pro Ser Asp Phe Thr Met 
        195                 200                 205             


Asn Asp 
    210 


<210>  1100
<211>  419
<212>  PRT
<213>  Homo Sapiens

<400>  1100

Ala Asn Ser Phe Leu Glu Glu Leu Arg His Ser Ser Leu Glu Arg Glu 
1               5                   10                  15      


Cys Ile Glu Glu Ile Cys Asp Phe Glu Glu Ala Lys Glu Ile Phe Gln 
            20                  25                  30          


Asn Val Asp Asp Thr Leu Ala Phe Trp Ser Lys His Val Asp Gly Asp 
        35                  40                  45              


Gln Cys Leu Val Leu Pro Leu Glu His Pro Cys Ala Ser Leu Cys Cys 
    50                  55                  60                  


Gly His Gly Thr Cys Ile Asp Gly Ile Gly Ser Phe Ser Cys Asp Cys 
65                  70                  75                  80  


Arg Ser Gly Trp Glu Gly Arg Phe Cys Gln Arg Glu Val Ser Phe Leu 
                85                  90                  95      


Asn Cys Ser Leu Asp Asn Gly Gly Cys Thr His Tyr Cys Leu Glu Glu 
            100                 105                 110         


Val Gly Trp Arg Arg Cys Ser Cys Ala Pro Gly Tyr Lys Leu Gly Asp 
        115                 120                 125             


Asp Leu Leu Gln Cys His Pro Ala Val Lys Phe Pro Cys Gly Arg Pro 
    130                 135                 140                 


Trp Lys Arg Met Glu Lys Lys Arg Ser His Leu Lys Arg Asp Thr Glu 
145                 150                 155                 160 


Asp Gln Glu Asp Gln Val Asp Pro Arg Leu Ile Asp Gly Lys Met Thr 
                165                 170                 175     


Arg Arg Gly Asp Ser Pro Trp Gln Val Val Leu Leu Asp Ser Lys Lys 
            180                 185                 190         


Lys Leu Ala Cys Gly Ala Val Leu Ile His Pro Ser Trp Val Leu Thr 
        195                 200                 205             


Ala Ala His Cys Met Asp Glu Ser Lys Lys Leu Leu Val Arg Leu Gly 
    210                 215                 220                 


Glu Tyr Asp Leu Arg Arg Trp Glu Lys Trp Glu Leu Asp Leu Asp Ile 
225                 230                 235                 240 


Lys Glu Val Phe Val His Pro Asn Tyr Ser Lys Ser Thr Thr Asp Asn 
                245                 250                 255     


Asp Ile Ala Leu Leu His Leu Ala Gln Pro Ala Thr Leu Ser Gln Thr 
            260                 265                 270         


Ile Val Pro Ile Cys Leu Pro Asp Ser Gly Leu Ala Glu Arg Glu Leu 
        275                 280                 285             


Asn Gln Ala Gly Gln Glu Thr Leu Val Thr Gly Trp Gly Tyr His Ser 
    290                 295                 300                 


Ser Arg Glu Lys Glu Ala Lys Arg Asn Arg Thr Phe Val Leu Asn Phe 
305                 310                 315                 320 


Ile Lys Ile Pro Val Val Pro His Asn Glu Cys Ser Glu Val Met Ser 
                325                 330                 335     


Asn Met Val Ser Glu Asn Met Leu Cys Ala Gly Ile Leu Gly Asp Arg 
            340                 345                 350         


Gln Asp Ala Cys Glu Gly Asp Ser Gly Gly Pro Met Val Ala Ser Phe 
        355                 360                 365             


His Gly Thr Trp Phe Leu Val Gly Leu Val Ser Trp Gly Glu Gly Cys 
    370                 375                 380                 


Gly Leu Leu His Asn Tyr Gly Val Tyr Thr Lys Val Ser Arg Tyr Leu 
385                 390                 395                 400 


Asp Trp Ile His Gly His Ile Arg Asp Lys Glu Ala Pro Gln Lys Ser 
                405                 410                 415     


Trp Ala Pro 
            


<210>  1101
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  1101

Ser Gln Asp Ala Ser Asp Gly Leu Gln Arg Leu His Met Leu Gln Ile 
1               5                   10                  15      


Ser Tyr Phe Arg Asp Pro Tyr His Val Trp Tyr Gln Gly Asn Ala Ser 
            20                  25                  30          


Leu Gly Gly His Leu Thr His Val Leu Glu Gly Pro Asp Thr Asn Thr 
        35                  40                  45              


Thr Ile Ile Gln Leu Gln Pro Leu Gln Glu Pro Glu Ser Trp Ala Arg 
    50                  55                  60                  


Thr Gln Ser Gly Leu Gln Ser Tyr Leu Leu Gln Phe His Gly Leu Val 
65                  70                  75                  80  


Arg Leu Val His Gln Glu Arg Thr Leu Ala Phe Pro Leu Thr Ile Arg 
                85                  90                  95      


Cys Phe Leu Gly Cys Glu Leu Pro Pro Glu Gly Ser Arg Ala His Val 
            100                 105                 110         


Phe Phe Glu Val Ala Val Asn Gly Ser Ser Phe Val Ser Phe Arg Pro 
        115                 120                 125             


Glu Arg Ala Leu Trp Gln Ala Asp Thr Gln Val Thr Ser Gly Val Val 
    130                 135                 140                 


Thr Phe Thr Leu Gln Gln Leu Asn Ala Tyr Asn Arg Thr Arg Tyr Glu 
145                 150                 155                 160 


Leu Arg Glu Phe Leu Glu Asp Thr Cys Val Gln Tyr Val Gln Lys His 
                165                 170                 175     


Ile Ser Ala Glu Asn Thr Lys Gly Ser Gln Thr Ser Arg Ser Tyr Thr 
            180                 185                 190         


Ser 
    


<210>  1102
<211>  635
<212>  PRT
<213>  Homo Sapiens

<400>  1102

Ala Asn Ser Leu Leu Glu Glu Thr Lys Gln Gly Asn Leu Glu Arg Glu 
1               5                   10                  15      


Cys Ile Glu Glu Leu Cys Asn Lys Glu Glu Ala Arg Glu Val Phe Glu 
            20                  25                  30          


Asn Asp Pro Glu Thr Asp Tyr Phe Tyr Pro Lys Tyr Leu Val Cys Leu 
        35                  40                  45              


Arg Ser Phe Gln Thr Gly Leu Phe Thr Ala Ala Arg Gln Ser Thr Asn 
    50                  55                  60                  


Ala Tyr Pro Asp Leu Arg Ser Cys Val Asn Ala Ile Pro Asp Gln Cys 
65                  70                  75                  80  


Ser Pro Leu Pro Cys Asn Glu Asp Gly Tyr Met Ser Cys Lys Asp Gly 
                85                  90                  95      


Lys Ala Ser Phe Thr Cys Thr Cys Lys Pro Gly Trp Gln Gly Glu Lys 
            100                 105                 110         


Cys Glu Phe Asp Ile Asn Glu Cys Lys Asp Pro Ser Asn Ile Asn Gly 
        115                 120                 125             


Gly Cys Ser Gln Ile Cys Asp Asn Thr Pro Gly Ser Tyr His Cys Ser 
    130                 135                 140                 


Cys Lys Asn Gly Phe Val Met Leu Ser Asn Lys Lys Asp Cys Lys Asp 
145                 150                 155                 160 


Val Asp Glu Cys Ser Leu Lys Pro Ser Ile Cys Gly Thr Ala Val Cys 
                165                 170                 175     


Lys Asn Ile Pro Gly Asp Phe Glu Cys Glu Cys Pro Glu Gly Tyr Arg 
            180                 185                 190         


Tyr Asn Leu Lys Ser Lys Ser Cys Glu Asp Ile Asp Glu Cys Ser Glu 
        195                 200                 205             


Asn Met Cys Ala Gln Leu Cys Val Asn Tyr Pro Gly Gly Tyr Thr Cys 
    210                 215                 220                 


Tyr Cys Asp Gly Lys Lys Gly Phe Lys Leu Ala Gln Asp Gln Lys Ser 
225                 230                 235                 240 


Cys Glu Val Val Ser Val Cys Leu Pro Leu Asn Leu Asp Thr Lys Tyr 
                245                 250                 255     


Glu Leu Leu Tyr Leu Ala Glu Gln Phe Ala Gly Val Val Leu Tyr Leu 
            260                 265                 270         


Lys Phe Arg Leu Pro Glu Ile Ser Arg Phe Ser Ala Glu Phe Asp Phe 
        275                 280                 285             


Arg Thr Tyr Asp Ser Glu Gly Val Ile Leu Tyr Ala Glu Ser Ile Asp 
    290                 295                 300                 


His Ser Ala Trp Leu Leu Ile Ala Leu Arg Gly Gly Lys Ile Glu Val 
305                 310                 315                 320 


Gln Leu Lys Asn Glu His Thr Ser Lys Ile Thr Thr Gly Gly Asp Val 
                325                 330                 335     


Ile Asn Asn Gly Leu Trp Asn Met Val Ser Val Glu Glu Leu Glu His 
            340                 345                 350         


Ser Ile Ser Ile Lys Ile Ala Lys Glu Ala Val Met Asp Ile Asn Lys 
        355                 360                 365             


Pro Gly Pro Leu Phe Lys Pro Glu Asn Gly Leu Leu Glu Thr Lys Val 
    370                 375                 380                 


Tyr Phe Ala Gly Phe Pro Arg Lys Val Glu Ser Glu Leu Ile Lys Pro 
385                 390                 395                 400 


Ile Asn Pro Arg Leu Asp Gly Cys Ile Arg Ser Trp Asn Leu Met Lys 
                405                 410                 415     


Gln Gly Ala Ser Gly Ile Lys Glu Ile Ile Gln Glu Lys Gln Asn Lys 
            420                 425                 430         


His Cys Leu Val Thr Val Glu Lys Gly Ser Tyr Tyr Pro Gly Ser Gly 
        435                 440                 445             


Ile Ala Gln Phe His Ile Asp Tyr Asn Asn Val Ser Ser Ala Glu Gly 
    450                 455                 460                 


Trp His Val Asn Val Thr Leu Asn Ile Arg Pro Ser Thr Gly Thr Gly 
465                 470                 475                 480 


Val Met Leu Ala Leu Val Ser Gly Asn Asn Thr Val Pro Phe Ala Val 
                485                 490                 495     


Ser Leu Val Asp Ser Thr Ser Glu Lys Ser Gln Asp Ile Leu Leu Ser 
            500                 505                 510         


Val Glu Asn Thr Val Ile Tyr Arg Ile Gln Ala Leu Ser Leu Cys Ser 
        515                 520                 525             


Asp Gln Gln Ser His Leu Glu Phe Arg Val Asn Arg Asn Asn Leu Glu 
    530                 535                 540                 


Leu Ser Thr Pro Leu Lys Ile Glu Thr Ile Ser His Glu Asp Leu Gln 
545                 550                 555                 560 


Arg Gln Leu Ala Val Leu Asp Lys Ala Met Lys Ala Lys Val Ala Thr 
                565                 570                 575     


Tyr Leu Gly Gly Leu Pro Asp Val Pro Phe Ser Ala Thr Pro Val Asn 
            580                 585                 590         


Ala Phe Tyr Asn Gly Cys Met Glu Val Asn Ile Asn Gly Val Gln Leu 
        595                 600                 605             


Asp Leu Asp Glu Ala Ile Ser Lys His Asn Asp Ile Arg Ala His Ser 
    610                 615                 620                 


Cys Pro Ser Val Trp Lys Lys Thr Lys Asn Ser 
625                 630                 635 


<210>  1103
<211>  360
<212>  PRT
<213>  Homo Sapiens

<400>  1103

Ala Gly Ser Tyr Leu Leu Glu Glu Leu Phe Glu Gly Asn Leu Glu Lys 
1               5                   10                  15      


Glu Cys Tyr Glu Glu Ile Cys Val Tyr Glu Glu Ala Arg Glu Val Phe 
            20                  25                  30          


Glu Asn Glu Val Val Thr Asp Glu Phe Trp Arg Arg Tyr Lys Gly Gly 
        35                  40                  45              


Ser Pro Cys Ile Ser Gln Pro Cys Leu His Asn Gly Ser Cys Gln Asp 
    50                  55                  60                  


Ser Ile Trp Gly Tyr Thr Cys Thr Cys Ser Pro Gly Tyr Glu Gly Ser 
65                  70                  75                  80  


Asn Cys Glu Leu Ala Lys Asn Glu Cys His Pro Glu Arg Thr Asp Gly 
                85                  90                  95      


Cys Gln His Phe Cys Leu Pro Gly Gln Glu Ser Tyr Thr Cys Ser Cys 
            100                 105                 110         


Ala Gln Gly Tyr Arg Leu Gly Glu Asp His Lys Gln Cys Val Pro His 
        115                 120                 125             


Asp Gln Cys Ala Cys Gly Val Leu Thr Ser Glu Lys Arg Ala Pro Asp 
    130                 135                 140                 


Leu Gln Asp Leu Pro Trp Gln Val Lys Leu Thr Asn Ser Glu Gly Lys 
145                 150                 155                 160 


Asp Phe Cys Gly Gly Val Ile Ile Arg Glu Asn Phe Val Leu Thr Thr 
                165                 170                 175     


Ala Lys Cys Ser Leu Leu His Arg Asn Ile Thr Val Lys Thr Tyr Phe 
            180                 185                 190         


Asn Arg Thr Ser Gln Asp Pro Leu Met Ile Lys Ile Thr His Val His 
        195                 200                 205             


Val His Met Arg Tyr Asp Ala Asp Ala Gly Glu Asn Asp Leu Ser Leu 
    210                 215                 220                 


Leu Glu Leu Glu Trp Pro Ile Gln Cys Pro Gly Ala Gly Leu Pro Val 
225                 230                 235                 240 


Cys Thr Pro Glu Lys Asp Phe Ala Glu His Leu Leu Ile Pro Arg Thr 
                245                 250                 255     


Arg Gly Leu Leu Ser Gly Trp Ala Arg Asn Gly Thr Asp Leu Gly Asn 
            260                 265                 270         


Ser Leu Thr Thr Arg Pro Val Thr Leu Val Glu Gly Glu Glu Cys Gly 
        275                 280                 285             


Gln Val Leu Asn Val Thr Val Thr Thr Arg Thr Tyr Cys Glu Arg Ser 
    290                 295                 300                 


Ser Val Ala Ala Met His Trp Met Asp Gly Ser Val Val Thr Arg Glu 
305                 310                 315                 320 


His Arg Gly Ser Trp Phe Leu Thr Gly Val Leu Gly Ser Gln Pro Val 
                325                 330                 335     


Gly Gly Gln Ala His Met Val Leu Val Thr Lys Val Ser Arg Tyr Ser 
            340                 345                 350         


Leu Trp Phe Lys Gln Ile Met Asn 
        355                 360 


<210>  1104
<211>  914
<212>  PRT
<213>  Homo Sapiens

<400>  1104

Phe Ser Glu Leu Ser Phe Val Lys Glu Pro Gln Asp Val Thr Val Thr 
1               5                   10                  15      


Arg Lys Asp Pro Val Val Leu Asp Cys Gln Ala His Gly Glu Val Pro 
            20                  25                  30          


Ile Lys Val Thr Trp Leu Lys Asn Gly Ala Lys Met Ser Glu Asn Lys 
        35                  40                  45              


Arg Ile Glu Val Leu Ser Asn Gly Ser Leu Tyr Ile Ser Glu Val Glu 
    50                  55                  60                  


Gly Arg Arg Gly Glu Gln Ser Asp Glu Gly Phe Tyr Gln Cys Leu Ala 
65                  70                  75                  80  


Met Asn Lys Tyr Gly Ala Ile Leu Ser Gln Lys Ala His Leu Ala Leu 
                85                  90                  95      


Ser Thr Ile Ser Ala Phe Glu Val Gln Pro Ile Ser Thr Glu Val His 
            100                 105                 110         


Glu Gly Gly Val Ala Arg Phe Ala Cys Lys Ile Ser Ser His Pro Pro 
        115                 120                 125             


Ala Val Ile Thr Trp Glu Phe Asn Arg Thr Thr Leu Pro Met Thr Met 
    130                 135                 140                 


Asp Arg Ile Thr Ala Leu Pro Thr Gly Val Leu Gln Ile Tyr Asp Val 
145                 150                 155                 160 


Ser Gln Arg Asp Ser Gly Asn Tyr Arg Cys Ile Ala Ala Thr Val Ala 
                165                 170                 175     


His Arg Arg Lys Ser Met Glu Ala Ser Leu Thr Val Ile Pro Ala Lys 
            180                 185                 190         


Glu Ser Lys Ser Phe His Thr Pro Thr Ile Ile Ala Gly Pro Gln Asn 
        195                 200                 205             


Ile Thr Thr Ser Leu His Gln Thr Val Val Leu Glu Cys Met Ala Thr 
    210                 215                 220                 


Gly Asn Pro Lys Pro Ile Ile Ser Trp Ser Arg Leu Asp His Lys Ser 
225                 230                 235                 240 


Ile Asp Val Phe Asn Thr Arg Val Leu Gly Asn Gly Asn Leu Met Ile 
                245                 250                 255     


Ser Asp Val Arg Leu Gln His Ala Gly Val Tyr Val Cys Arg Ala Thr 
            260                 265                 270         


Thr Pro Gly Thr Arg Asn Phe Thr Val Ala Met Ala Thr Leu Thr Val 
        275                 280                 285             


Leu Ala Pro Pro Ser Phe Val Glu Trp Pro Glu Ser Leu Thr Arg Pro 
    290                 295                 300                 


Arg Ala Gly Thr Ala Arg Phe Val Cys Gln Ala Glu Gly Ile Pro Ser 
305                 310                 315                 320 


Pro Lys Met Ser Trp Leu Lys Asn Gly Arg Lys Ile His Ser Asn Gly 
                325                 330                 335     


Arg Ile Lys Met Tyr Asn Ser Lys Leu Val Ile Asn Gln Ile Ile Pro 
            340                 345                 350         


Glu Asp Asp Ala Ile Tyr Gln Cys Met Ala Glu Asn Ser Gln Gly Ser 
        355                 360                 365             


Ile Leu Ser Arg Ala Arg Leu Thr Val Val Met Ser Glu Asp Arg Pro 
    370                 375                 380                 


Ser Ala Pro Tyr Asn Val His Ala Glu Thr Met Ser Ser Ser Ala Ile 
385                 390                 395                 400 


Leu Leu Ala Trp Glu Arg Pro Leu Tyr Asn Ser Asp Lys Val Ile Ala 
                405                 410                 415     


Tyr Ser Val His Tyr Met Lys Ala Glu Gly Leu Asn Asn Glu Glu Tyr 
            420                 425                 430         


Gln Val Val Ile Gly Asn Asp Thr Thr His Tyr Ile Ile Asp Asp Leu 
        435                 440                 445             


Glu Pro Ala Ser Asn Tyr Thr Phe Tyr Ile Val Ala Tyr Met Pro Met 
    450                 455                 460                 


Gly Ala Ser Gln Met Ser Asp His Val Thr Gln Asn Thr Leu Glu Asp 
465                 470                 475                 480 


Val Pro Leu Arg Pro Pro Glu Ile Ser Leu Thr Ser Arg Ser Pro Thr 
                485                 490                 495     


Asp Ile Leu Ile Ser Trp Leu Pro Ile Pro Ala Lys Tyr Arg Arg Gly 
            500                 505                 510         


Gln Val Val Leu Tyr Arg Leu Ser Phe Arg Leu Ser Thr Glu Asn Ser 
        515                 520                 525             


Ile Gln Val Leu Glu Leu Pro Gly Thr Thr His Glu Tyr Leu Leu Glu 
    530                 535                 540                 


Gly Leu Lys Pro Asp Ser Val Tyr Leu Val Arg Ile Thr Ala Ala Thr 
545                 550                 555                 560 


Arg Val Gly Leu Gly Glu Ser Ser Val Trp Thr Ser His Arg Thr Pro 
                565                 570                 575     


Lys Ala Thr Ser Val Lys Ala Pro Lys Ser Pro Glu Leu His Leu Glu 
            580                 585                 590         


Pro Leu Asn Cys Thr Thr Ile Ser Val Arg Trp Gln Gln Asp Val Glu 
        595                 600                 605             


Asp Thr Ala Ala Ile Gln Gly Tyr Lys Leu Tyr Tyr Lys Glu Glu Gly 
    610                 615                 620                 


Gln Gln Glu Asn Gly Pro Ile Phe Leu Asp Thr Lys Asp Leu Leu Tyr 
625                 630                 635                 640 


Thr Leu Ser Gly Leu Asp Pro Arg Arg Lys Tyr His Val Arg Leu Leu 
                645                 650                 655     


Ala Tyr Asn Asn Ile Asp Asp Gly Tyr Gln Ala Asp Gln Thr Val Ser 
            660                 665                 670         


Thr Pro Gly Cys Val Ser Val Arg Asp Arg Met Val Pro Pro Pro Pro 
        675                 680                 685             


Pro Pro His His Leu Tyr Ala Lys Ala Asn Thr Ser Ser Ser Ile Phe 
    690                 695                 700                 


Leu His Trp Arg Arg Pro Ala Phe Thr Ala Ala Gln Ile Ile Asn Tyr 
705                 710                 715                 720 


Thr Ile Arg Cys Asn Pro Val Gly Leu Gln Asn Ala Ser Leu Val Leu 
                725                 730                 735     


Tyr Leu Gln Thr Ser Glu Thr His Met Leu Val Gln Gly Leu Glu Pro 
            740                 745                 750         


Asn Thr Lys Tyr Glu Phe Ala Val Arg Leu His Val Asp Gln Leu Ser 
        755                 760                 765             


Ser Pro Trp Ser Pro Val Val Tyr His Ser Thr Leu Pro Glu Ala Pro 
    770                 775                 780                 


Ala Gly Pro Pro Val Gly Val Lys Val Thr Leu Ile Glu Asp Asp Thr 
785                 790                 795                 800 


Ala Leu Val Ser Trp Lys Pro Pro Asp Gly Pro Glu Thr Val Val Thr 
                805                 810                 815     


Arg Tyr Thr Ile Leu Tyr Ala Ser Arg Lys Ala Trp Ile Ala Gly Glu 
            820                 825                 830         


Trp Gln Val Leu His Arg Glu Gly Ala Ile Thr Met Ala Leu Leu Glu 
        835                 840                 845             


Asn Leu Val Ala Gly Asn Val Tyr Ile Val Lys Ile Ser Ala Ser Asn 
    850                 855                 860                 


Glu Val Gly Glu Gly Pro Phe Ser Asn Ser Val Glu Leu Ala Val Leu 
865                 870                 875                 880 


Pro Lys Glu Thr Ser Glu Ser Asn Gln Arg Pro Lys Arg Leu Asp Ser 
                885                 890                 895     


Ala Asp Ala Lys Val Tyr Ser Gly Tyr Tyr His Leu Asp Gln Lys Ser 
            900                 905                 910         


Met Thr 
        


<210>  1105
<211>  387
<212>  PRT
<213>  Homo Sapiens

<400>  1105

Leu Leu Cys Gln Phe Gly Thr Val Gln His Val Trp Lys Val Ser Asp 
1               5                   10                  15      


Leu Pro Arg Gln Trp Thr Pro Lys Asn Thr Ser Cys Asp Ser Gly Leu 
            20                  25                  30          


Gly Cys Gln Asp Thr Leu Met Leu Ile Glu Ser Gly Pro Gln Val Ser 
        35                  40                  45              


Leu Val Leu Ser Lys Gly Cys Thr Glu Ala Lys Asp Gln Glu Pro Arg 
    50                  55                  60                  


Val Thr Glu His Arg Met Gly Pro Gly Leu Ser Leu Ile Ser Tyr Thr 
65                  70                  75                  80  


Phe Val Cys Arg Gln Glu Asp Phe Cys Asn Asn Leu Val Asn Ser Leu 
                85                  90                  95      


Pro Leu Trp Ala Pro Gln Pro Pro Ala Asp Pro Gly Ser Leu Arg Cys 
            100                 105                 110         


Pro Val Cys Leu Ser Met Glu Gly Cys Leu Glu Gly Thr Thr Glu Glu 
        115                 120                 125             


Ile Cys Pro Lys Gly Thr Thr His Cys Tyr Asp Gly Leu Leu Arg Leu 
    130                 135                 140                 


Arg Gly Gly Gly Ile Phe Ser Asn Leu Arg Val Gln Gly Cys Met Pro 
145                 150                 155                 160 


Gln Pro Gly Cys Asn Leu Leu Asn Gly Thr Gln Glu Ile Gly Pro Val 
                165                 170                 175     


Gly Met Thr Glu Asn Cys Asn Arg Lys Asp Phe Leu Thr Cys His Arg 
            180                 185                 190         


Gly Thr Thr Ile Met Thr His Gly Asn Leu Ala Gln Glu Pro Thr Asp 
        195                 200                 205             


Trp Thr Thr Ser Asn Thr Glu Met Cys Glu Val Gly Gln Val Cys Gln 
    210                 215                 220                 


Glu Thr Leu Leu Leu Ile Asp Val Gly Leu Thr Ser Thr Leu Val Gly 
225                 230                 235                 240 


Thr Lys Gly Cys Ser Thr Val Gly Ala Gln Asn Ser Gln Lys Thr Thr 
                245                 250                 255     


Ile His Ser Ala Pro Pro Gly Val Leu Val Ala Ser Tyr Thr His Phe 
            260                 265                 270         


Cys Ser Ser Asp Leu Cys Asn Ser Ala Ser Ser Ser Ser Val Leu Leu 
        275                 280                 285             


Asn Ser Leu Pro Pro Gln Ala Ala Pro Val Pro Gly Asp Arg Gln Cys 
    290                 295                 300                 


Pro Thr Cys Val Gln Pro Leu Gly Thr Cys Ser Ser Gly Ser Pro Arg 
305                 310                 315                 320 


Met Thr Cys Pro Arg Gly Ala Thr His Cys Tyr Asp Gly Tyr Ile His 
                325                 330                 335     


Leu Ser Gly Gly Gly Leu Ser Thr Lys Met Ser Ile Gln Gly Cys Val 
            340                 345                 350         


Ala Gln Pro Ser Ser Phe Leu Leu Asn His Thr Arg Gln Ile Gly Ile 
        355                 360                 365             


Phe Ser Ala Arg Glu Lys Arg Asp Val Gln Pro Pro Ala Ser Gln His 
    370                 375                 380                 


Glu Gly Gly 
385         


<210>  1106
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  1106

Leu Leu Cys Tyr Ser Cys Lys Ala Gln Val Ser Asn Glu Asp Cys Leu 
1               5                   10                  15      


Gln Val Glu Asn Cys Thr Gln Leu Gly Glu Gln Cys Trp Thr Ala Arg 
            20                  25                  30          


Ile Arg Ala Val Gly Leu Leu Thr Val Ile Ser Lys Gly Cys Ser Leu 
        35                  40                  45              


Asn Cys Val Asp Asp Ser Gln Asp Tyr Tyr Val Gly Lys Lys Asn Ile 
    50                  55                  60                  


Thr Cys Cys Asp Thr Asp Leu Cys Asn Ala Ser 
65                  70                  75  


<210>  1107
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  1107

Gln Val Thr Ile Glu Ala Glu Pro Thr Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Met Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Glu Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Gly Asp Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Arg Phe Thr Phe Thr Leu His Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Thr Met 
        115                 120                 125             


Glu Ala Val Ser Leu Thr Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Ser Leu Lys 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Leu Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Pro Lys Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Asn Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Arg Asp Arg Tyr Gly Gly Ile Arg Ser Asp 
        275                 280                 285             


Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Arg Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Val Leu Tyr Leu Ser Cys 
305                 310                 315                 320 


Ser Ala Asp Ser Asn Pro Pro Ala Gln Tyr Ser Trp Thr Ile Asn Glu 
                325                 330                 335     


Lys Phe Gln Leu Pro Gly Gln Lys Leu Phe Ile Arg His Ile Thr Thr 
            340                 345                 350         


Lys His Ser Gly Leu Tyr Val Cys Ser Val Arg Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ser Ser Lys Ser Met Thr Val Glu Val Ser Asp Trp Thr Val 
    370                 375                 380                 


Pro 
385 


<210>  1108
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  1108

Gln Val Thr Ile Glu Ala Glu Pro Thr Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Met Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Glu Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Gly Asp Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Arg Phe Thr Phe Thr Leu His Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Thr Met 
        115                 120                 125             


Glu Ala Val Ser Leu Thr Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Ser Leu Lys 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Leu Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Pro Lys Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Asn Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Arg Asp Arg Tyr Gly Gly Ile Arg Ser Asp 
        275                 280                 285             


Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Arg Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Val Leu Tyr Leu Ser Cys 
305                 310                 315                 320 


Ser Ala Asp Ser Asn Pro Pro Ala Gln Tyr Ser Trp Thr Ile Asn Glu 
                325                 330                 335     


Lys Phe Gln Leu Pro Gly Gln Lys Leu Phe Ile Arg His Ile Thr Thr 
            340                 345                 350         


Lys His Ser Gly Leu Tyr Val Cys Ser Val Arg Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ser Ser Lys Ser Met Thr Val Glu Val Ser Gly Lys Trp Ile 
    370                 375                 380                 


Pro Ala Ser Leu Ala Ile Gly Phe 
385                 390         


<210>  1109
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  1109

Gln Val Thr Ile Glu Ala Gln Pro Pro Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Ile Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Gln Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Arg Gly Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Tyr Phe Thr Phe Thr Leu Tyr Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Ala Met 
        115                 120                 125             


Glu Thr Val Ile Leu Thr Cys Asp Pro Glu Thr Pro Asp Thr Ser Tyr 
    130                 135                 140                 


Gln Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Arg Phe Gln 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Phe Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Ser Gly Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu His Gly Pro Asp Leu Pro 
        195                 200                 205             


Arg Ile His Pro Ser Tyr Thr Asn Tyr Arg Ser Gly Asp Asn Leu Tyr 
    210                 215                 220                 


Leu Ser Cys Phe Ala Asn Ser Asn Pro Pro Ala Gln Tyr Ser Trp Thr 
225                 230                 235                 240 


Ile Asn Gly Lys Phe Gln Gln Ser Gly Gln Asn Leu Phe Ile Pro Gln 
                245                 250                 255     


Ile Thr Thr Lys His Ser Gly Leu Tyr Val Cys Ser Val Arg Asn Ser 
            260                 265                 270         


Ala Thr Gly Glu Glu Ser Ser Thr Ser Leu Thr Val Lys Val Ser Ala 
        275                 280                 285             


Ser Thr Arg Ile Gly Leu Leu Pro Leu Leu Asn Pro Thr Trp Ile His 
    290                 295                 300                 


Pro Ala Phe Leu Tyr 
305                 


<210>  1110
<211>  301
<212>  PRT
<213>  Homo Sapiens

<400>  1110

Gln Val Thr Ile Glu Ala Gln Pro Pro Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Ile Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Gln Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Arg Gly Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Tyr Phe Thr Phe Thr Leu Tyr Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Ala Met 
        115                 120                 125             


Glu Thr Val Ile Leu Thr Cys Asp Pro Glu Thr Pro Asp Thr Ser Tyr 
    130                 135                 140                 


Gln Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Arg Phe Gln 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Phe Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Ser Gly Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu His Gly Pro Asp Leu Pro 
        195                 200                 205             


Arg Ile His Pro Ser Tyr Thr Asn Tyr Arg Ser Gly Asp Asn Leu Tyr 
    210                 215                 220                 


Leu Ser Cys Phe Ala Asn Ser Asn Pro Pro Ala Gln Tyr Ser Trp Thr 
225                 230                 235                 240 


Ile Asn Gly Lys Phe Gln Gln Ser Gly Gln Asn Leu Phe Ile Pro Gln 
                245                 250                 255     


Ile Thr Thr Lys His Ser Gly Leu Tyr Val Cys Ser Val Arg Asn Ser 
            260                 265                 270         


Ala Thr Gly Glu Glu Ser Ser Thr Ser Leu Thr Val Lys Val Ser Ala 
        275                 280                 285             


Ser Thr Arg Ile Gly Leu Leu Pro Leu Leu Asn Pro Thr 
    290                 295                 300     


<210>  1111
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  1111

Gln Val Thr Ile Glu Ala Glu Pro Thr Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Met Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Glu Ile Ile Ile Tyr Gly Pro Ala Tyr Gly Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Gly Asp Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Arg Phe Thr Phe Thr Leu His Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Thr Met 
        115                 120                 125             


Glu Ala Val Ser Leu Thr Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Ser Leu Lys 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Leu Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Ser Lys Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Thr Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Asn Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Arg Asp Arg Tyr Gly Gly Ile Arg Ser Asp 
        275                 280                 285             


Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Ser Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Asn Leu Tyr Leu Ser Cys 
305                 310                 315                 320 


Phe Ala Glu Ser Asn Pro Arg Ala Gln Tyr Ser Trp Thr Ile Asn Gly 
                325                 330                 335     


Lys Phe Gln Leu Ser Gly Gln Lys Leu Ser Ile Pro Gln Ile Thr Thr 
            340                 345                 350         


Lys His Ser Gly Leu Tyr Ala Cys Ser Val Arg Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ser Ser Lys Ser Ile Thr Val Lys Val Ser Asp Trp Ile Leu 
    370                 375                 380                 


Pro 
385 


<210>  1112
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  1112

Gln Val Thr Ile Glu Ala Glu Pro Thr Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Met Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Glu Ile Ile Ile Tyr Gly Pro Ala Tyr Gly Gly Arg 
    50                  55                  60                  


Glu Thr Ala Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Gly Asp Asp Gly 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Arg Phe Thr Phe Thr Leu His Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Thr Met 
        115                 120                 125             


Glu Ala Val Ser Leu Thr Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Met Thr His Ser Leu Lys 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Leu Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Ser Lys Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Thr Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Asn Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Arg Asp Arg Tyr Gly Gly Ile Arg Ser Asp 
        275                 280                 285             


Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Ser Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Asn Leu Tyr Leu Ser Cys 
305                 310                 315                 320 


Phe Ala Glu Ser Asn Pro Arg Ala Gln Tyr Ser Trp Thr Ile Asn Gly 
                325                 330                 335     


Lys Phe Gln Leu Ser Gly Gln Lys Leu Ser Ile Pro Gln Ile Thr Thr 
            340                 345                 350         


Lys His Ser Gly Leu Tyr Ala Cys Ser Val Arg Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ser Ser Lys Ser Ile Thr Val Lys Val Ser Asp Trp Ile Leu 
    370                 375                 380                 


Pro 
385 


<210>  1113
<211>  301
<212>  PRT
<213>  Homo Sapiens

<400>  1113

Gln Val Thr Ile Glu Ala Leu Pro Pro Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Ala Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Leu Met Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Gln Ile Asn Ile Tyr Gly Pro Ala Tyr Thr Gly Arg 
    50                  55                  60                  


Glu Thr Val Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Arg Gly Asp Arg 
                85                  90                  95      


Thr Arg Gly Val Thr Gly Tyr Phe Thr Phe Asn Leu Tyr Leu Lys Leu 
            100                 105                 110         


Pro Lys Pro Tyr Ile Thr Ile Asn Asn Ser Lys Pro Arg Glu Asn Lys 
        115                 120                 125             


Asp Val Leu Ala Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr 
    130                 135                 140                 


Ile Trp Trp Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys 
145                 150                 155                 160 


Gln Pro Ile Glu Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn 
                165                 170                 175     


Glu Thr Gly Pro Tyr Glu Cys Glu Ile Arg Asp Arg Asp Gly Gly Met 
            180                 185                 190         


His Ser Asp Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro 
        195                 200                 205             


Ser Ile Tyr Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Asn Leu Tyr 
    210                 215                 220                 


Leu Ser Cys Phe Ala Glu Ser Asn Pro Pro Ala Glu Tyr Phe Trp Thr 
225                 230                 235                 240 


Ile Asn Gly Lys Phe Gln Gln Ser Gly Gln Lys Leu Ser Ile Pro Gln 
                245                 250                 255     


Ile Thr Thr Lys His Arg Gly Leu Tyr Thr Cys Ser Val Arg Asn Ser 
            260                 265                 270         


Ala Thr Gly Lys Glu Ser Ser Lys Ser Met Thr Val Glu Val Ser Ala 
        275                 280                 285             


Pro Ser Gly Ile Gly Arg Leu Pro Leu Leu Asn Pro Ile 
    290                 295                 300     


<210>  1114
<211>  390
<212>  PRT
<213>  Homo Sapiens

<400>  1114

Gln Val Ile Ile Glu Ala Lys Pro Pro Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Met Thr Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val His Gly Gln Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg Glu 
    50                  55                  60                  


Thr Val Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Gln Glu 
65                  70                  75                  80  


Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Lys Arg Gly Asp Gly Thr 
                85                  90                  95      


Gly Gly Val Thr Gly Tyr Phe Thr Val Thr Leu Tyr Ser Glu Thr Pro 
            100                 105                 110         


Lys Pro Ser Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Val Met Glu 
        115                 120                 125             


Ala Val Arg Leu Ile Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr Leu 
    130                 135                 140                 


Trp Leu Leu Asn Gly Gln Asn Leu Pro Met Thr His Arg Leu Gln Leu 
145                 150                 155                 160 


Ser Lys Thr Asn Arg Thr Leu Tyr Leu Phe Gly Val Thr Lys Tyr Ile 
                165                 170                 175     


Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser Arg 
            180                 185                 190         


Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Pro Met Pro Tyr 
        195                 200                 205             


Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Lys Lys Asp Val Leu Ala 
    210                 215                 220                 


Phe Thr Cys Glu Pro Lys Ser Arg Asn Tyr Thr Tyr Ile Trp Trp Leu 
225                 230                 235                 240 


Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile Glu 
                245                 250                 255     


Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn Glu Thr Gly Pro 
            260                 265                 270         


Tyr Gln Cys Glu Ile Arg Asp Arg Tyr Gly Gly Ile Arg Ser Asn Pro 
        275                 280                 285             


Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Arg Ile Tyr Pro 
    290                 295                 300                 


Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Asn Leu Asp Leu Ser Cys Phe 
305                 310                 315                 320 


Ala Asp Ser Asn Pro Pro Ala Glu Tyr Ser Trp Thr Ile Asn Gly Lys 
                325                 330                 335     


Phe Gln Leu Ser Gly Gln Lys Leu Phe Ile Pro Gln Ile Thr Thr Asn 
            340                 345                 350         


His Ser Gly Leu Tyr Ala Cys Ser Val Arg Asn Ser Ala Thr Gly Lys 
        355                 360                 365             


Glu Ile Ser Lys Ser Met Ile Val Lys Val Ser Gly Pro Cys His Gly 
    370                 375                 380                 


Asn Gln Thr Glu Ser His 
385                 390 


<210>  1115
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  1115

Gln Val Thr Ile Glu Ala Gln Pro Thr Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Thr Gly Tyr Ile 
            20                  25                  30          


Trp Tyr Lys Gly Gln Ile Arg Asp Leu Tyr His Tyr Ile Thr Ser Tyr 
        35                  40                  45              


Val Val Asp Gly Gln Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Ile Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Gln 
65                  70                  75                  80  


Glu Asp Ala Gly Ser Tyr Thr Leu His Ile Ile Met Gly Gly Asp Glu 
                85                  90                  95      


Asn Arg Gly Val Thr Gly His Phe Thr Phe Thr Leu Tyr Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Ser Ile Ser Ser Ser Lys Leu Asn Pro Arg Glu Ala Met 
        115                 120                 125             


Glu Ala Val Ser Leu Thr Cys Asp Pro Glu Thr Pro Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Met Ser His Arg Leu Gln 
145                 150                 155                 160 


Leu Ser Glu Thr Asn Arg Thr Leu Phe Leu Leu Gly Val Thr Lys Tyr 
                165                 170                 175     


Thr Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Phe Thr Leu Asn Leu Leu Pro Lys Leu Pro Lys Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Lys Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Asn Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Arg Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Arg Asp Gln Tyr Gly Gly Ile Arg Ser Tyr 
        275                 280                 285             


Pro Val Thr Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Arg Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Val Leu Tyr Leu Ser Cys 
305                 310                 315                 320 


Ser Ala Asp Ser Asn Pro Pro Ala Gln Tyr Ser Trp Thr Ile Asn Gly 
                325                 330                 335     


Lys Phe Gln Leu Ser Gly Gln Lys Leu Phe Ile Pro Gln Ile Thr Thr 
            340                 345                 350         


Lys His Ser Gly Leu Tyr Ala Cys Ser Val Arg Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ser Ser Lys Ser Met Thr Val Lys Val Ser Gly Lys Arg Ile 
    370                 375                 380                 


Pro Val Ser Leu Ala Ile Gly Ile 
385                 390         


<210>  1116
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  1116

Glu Val Thr Ile Glu Ala Gln Pro Pro Lys Val Ser Glu Gly Lys Asp 
1               5                   10                  15      


Val Leu Leu Leu Val His Asn Leu Pro Gln Asn Leu Pro Gly Tyr Phe 
            20                  25                  30          


Trp Tyr Lys Gly Glu Met Thr Asp Leu Tyr His Tyr Ile Ile Ser Tyr 
        35                  40                  45              


Ile Val Asp Gly Lys Ile Ile Ile Tyr Gly Pro Ala Tyr Ser Gly Arg 
    50                  55                  60                  


Glu Thr Val Tyr Ser Asn Ala Ser Leu Leu Ile Gln Asn Val Thr Arg 
65                  70                  75                  80  


Lys Asp Ala Gly Thr Tyr Thr Leu His Ile Ile Lys Arg Gly Asp Glu 
                85                  90                  95      


Thr Arg Glu Glu Ile Arg His Phe Thr Phe Thr Leu Tyr Leu Glu Thr 
            100                 105                 110         


Pro Lys Pro Tyr Ile Ser Ser Ser Asn Leu Asn Pro Arg Glu Ala Met 
        115                 120                 125             


Glu Ala Val Arg Leu Ile Cys Asp Pro Glu Thr Leu Asp Ala Ser Tyr 
    130                 135                 140                 


Leu Trp Trp Met Asn Gly Gln Ser Leu Pro Val Thr His Arg Leu Gln 
145                 150                 155                 160 


Leu Ser Lys Thr Asn Arg Thr Leu Tyr Leu Phe Gly Val Thr Lys Tyr 
                165                 170                 175     


Ile Ala Gly Pro Tyr Glu Cys Glu Ile Arg Asn Pro Val Ser Ala Ser 
            180                 185                 190         


Arg Ser Asp Pro Val Thr Leu Asn Leu Leu Pro Lys Leu Pro Ile Pro 
        195                 200                 205             


Tyr Ile Thr Ile Asn Asn Leu Asn Pro Arg Glu Asn Lys Asp Val Leu 
    210                 215                 220                 


Ala Phe Thr Cys Glu Pro Lys Ser Glu Asn Tyr Thr Tyr Ile Trp Trp 
225                 230                 235                 240 


Leu Asn Gly Gln Ser Leu Pro Val Ser Pro Gly Val Lys Arg Pro Ile 
                245                 250                 255     


Glu Asn Arg Ile Leu Ile Leu Pro Ser Val Thr Arg Asn Glu Thr Gly 
            260                 265                 270         


Pro Tyr Gln Cys Glu Ile Gln Asp Arg Tyr Gly Gly Leu Arg Ser Asn 
        275                 280                 285             


Pro Val Ile Leu Asn Val Leu Tyr Gly Pro Asp Leu Pro Arg Ile Tyr 
    290                 295                 300                 


Pro Ser Phe Thr Tyr Tyr Arg Ser Gly Glu Asn Leu Asp Leu Ser Cys 
305                 310                 315                 320 


Phe Thr Glu Ser Asn Pro Pro Ala Glu Tyr Phe Trp Thr Ile Asn Gly 
                325                 330                 335     


Lys Phe Gln Gln Ser Gly Gln Lys Leu Phe Ile Pro Gln Ile Thr Arg 
            340                 345                 350         


Asn His Ser Gly Leu Tyr Ala Cys Ser Val His Asn Ser Ala Thr Gly 
        355                 360                 365             


Lys Glu Ile Ser Lys Ser Met Thr Val Lys Val Ser Gly Pro Cys His 
    370                 375                 380                 


Gly Asp Leu Thr Glu Ser Gln Ser 
385                 390         


<210>  1117
<211>  135
<212>  PRT
<213>  Homo Sapiens

<400>  1117

Trp Gly Pro Asp Ala Arg Gly Val Pro Val Ala Asp Gly Glu Phe Ser 
1               5                   10                  15      


Ser Glu Gln Val Ala Lys Ala Gly Gly Thr Trp Leu Gly Thr His Arg 
            20                  25                  30          


Pro Leu Ala Arg Leu Arg Arg Ala Leu Ser Gly Pro Cys Gln Leu Trp 
        35                  40                  45              


Ser Leu Thr Leu Ser Val Ala Glu Leu Gly Leu Gly Tyr Ala Ser Glu 
    50                  55                  60                  


Glu Lys Val Ile Phe Arg Tyr Cys Ala Gly Ser Cys Pro Arg Gly Ala 
65                  70                  75                  80  


Arg Thr Gln His Gly Leu Ala Leu Ala Arg Leu Gln Gly Gln Gly Arg 
                85                  90                  95      


Ala His Gly Gly Pro Cys Cys Arg Pro Thr Arg Tyr Thr Asp Val Ala 
            100                 105                 110         


Phe Leu Asp Asp Arg His Arg Trp Gln Arg Leu Pro Gln Leu Ser Ala 
        115                 120                 125             


Ala Ala Cys Gly Cys Gly Gly 
    130                 135 


<210>  1118
<211>  576
<212>  PRT
<213>  Homo Sapiens

<400>  1118

Ala Asp Pro Gly Ala Pro Thr Pro Val Asn Pro Cys Cys Tyr Tyr Pro 
1               5                   10                  15      


Cys Gln His Gln Gly Ile Cys Val Arg Phe Gly Leu Asp Arg Tyr Gln 
            20                  25                  30          


Cys Asp Cys Thr Arg Thr Gly Tyr Ser Gly Pro Asn Cys Thr Ile Pro 
        35                  40                  45              


Gly Leu Trp Thr Trp Leu Arg Asn Ser Leu Arg Pro Ser Pro Ser Phe 
    50                  55                  60                  


Thr His Phe Leu Leu Thr His Gly Arg Trp Phe Trp Glu Phe Val Asn 
65                  70                  75                  80  


Ala Thr Phe Ile Arg Glu Met Leu Met Arg Leu Val Leu Thr Val Arg 
                85                  90                  95      


Ser Asn Leu Ile Pro Ser Pro Pro Thr Tyr Asn Ser Ala His Asp Tyr 
            100                 105                 110         


Ile Ser Trp Glu Ser Phe Ser Asn Val Ser Tyr Tyr Thr Arg Ile Leu 
        115                 120                 125             


Pro Ser Val Pro Lys Asp Cys Pro Thr Pro Met Gly Thr Lys Gly Lys 
    130                 135                 140                 


Lys Gln Leu Pro Asp Ala Gln Leu Leu Ala Arg Arg Phe Leu Leu Arg 
145                 150                 155                 160 


Arg Lys Phe Ile Pro Asp Pro Gln Gly Thr Asn Leu Met Phe Ala Phe 
                165                 170                 175     


Phe Ala Gln His Phe Thr His Gln Phe Phe Lys Thr Ser Gly Lys Met 
            180                 185                 190         


Gly Pro Gly Phe Thr Lys Ala Leu Gly His Gly Val Asp Leu Gly His 
        195                 200                 205             


Ile Tyr Gly Asp Asn Leu Glu Arg Gln Tyr Gln Leu Arg Leu Phe Lys 
    210                 215                 220                 


Asp Gly Lys Leu Lys Tyr Gln Val Leu Asp Gly Glu Met Tyr Pro Pro 
225                 230                 235                 240 


Ser Val Glu Glu Ala Pro Val Leu Met His Tyr Pro Arg Gly Ile Pro 
                245                 250                 255     


Pro Gln Ser Gln Met Ala Val Gly Gln Glu Val Phe Gly Leu Leu Pro 
            260                 265                 270         


Gly Leu Met Leu Tyr Ala Thr Leu Trp Leu Arg Glu His Asn Arg Val 
        275                 280                 285             


Cys Asp Leu Leu Lys Ala Glu His Pro Thr Trp Gly Asp Glu Gln Leu 
    290                 295                 300                 


Phe Gln Thr Thr Arg Leu Ile Leu Ile Gly Glu Thr Ile Lys Ile Val 
305                 310                 315                 320 


Ile Glu Glu Tyr Val Gln Gln Leu Ser Gly Tyr Phe Leu Gln Leu Lys 
                325                 330                 335     


Phe Asp Pro Glu Leu Leu Phe Gly Val Gln Phe Gln Tyr Arg Asn Arg 
            340                 345                 350         


Ile Ala Met Glu Phe Asn His Leu Tyr His Trp His Pro Leu Met Pro 
        355                 360                 365             


Asp Ser Phe Lys Val Gly Ser Gln Glu Tyr Ser Tyr Glu Gln Phe Leu 
    370                 375                 380                 


Phe Asn Thr Ser Met Leu Val Asp Tyr Gly Val Glu Ala Leu Val Asp 
385                 390                 395                 400 


Ala Phe Ser Arg Gln Ile Ala Gly Arg Ile Gly Gly Gly Arg Asn Met 
                405                 410                 415     


Asp His His Ile Leu His Val Ala Val Asp Val Ile Arg Glu Ser Arg 
            420                 425                 430         


Glu Met Arg Leu Gln Pro Phe Asn Glu Tyr Arg Lys Arg Phe Gly Met 
        435                 440                 445             


Lys Pro Tyr Thr Ser Phe Gln Glu Leu Val Gly Glu Lys Glu Met Ala 
    450                 455                 460                 


Ala Glu Leu Glu Glu Leu Tyr Gly Asp Ile Asp Ala Leu Glu Phe Tyr 
465                 470                 475                 480 


Pro Gly Leu Leu Leu Glu Lys Cys His Pro Asn Ser Ile Phe Gly Glu 
                485                 490                 495     


Ser Met Ile Glu Ile Gly Ala Pro Phe Ser Leu Lys Gly Leu Leu Gly 
            500                 505                 510         


Asn Pro Ile Cys Ser Pro Glu Tyr Trp Lys Pro Ser Thr Phe Gly Gly 
        515                 520                 525             


Glu Val Gly Phe Asn Ile Val Lys Thr Ala Thr Leu Lys Lys Leu Val 
    530                 535                 540                 


Cys Leu Asn Thr Lys Thr Cys Pro Tyr Val Ser Phe Arg Val Pro Asp 
545                 550                 555                 560 


Ala Ser Gln Asp Asp Gly Pro Ala Val Glu Arg Pro Ser Thr Glu Leu 
                565                 570                 575     


<210>  1119
<211>  587
<212>  PRT
<213>  Homo Sapiens

<400>  1119

Ala Asn Pro Cys Cys Ser His Pro Cys Gln Asn Arg Gly Val Cys Met 
1               5                   10                  15      


Ser Val Gly Phe Asp Gln Tyr Lys Cys Asp Cys Thr Arg Thr Gly Phe 
            20                  25                  30          


Tyr Gly Glu Asn Cys Ser Thr Pro Glu Phe Leu Thr Arg Ile Lys Leu 
        35                  40                  45              


Phe Leu Lys Pro Thr Pro Asn Thr Val His Tyr Ile Leu Thr His Phe 
    50                  55                  60                  


Lys Gly Phe Trp Asn Val Val Asn Asn Ile Pro Phe Leu Arg Asn Ala 
65                  70                  75                  80  


Ile Met Ser Tyr Val Leu Thr Ser Arg Ser His Leu Ile Asp Ser Pro 
                85                  90                  95      


Pro Thr Tyr Asn Ala Asp Tyr Gly Tyr Lys Ser Trp Glu Ala Phe Ser 
            100                 105                 110         


Asn Leu Ser Tyr Tyr Thr Arg Ala Leu Pro Pro Val Pro Asp Asp Cys 
        115                 120                 125             


Pro Thr Pro Leu Gly Val Lys Gly Lys Lys Gln Leu Pro Asp Ser Asn 
    130                 135                 140                 


Glu Ile Val Glu Lys Leu Leu Leu Arg Arg Lys Phe Ile Pro Asp Pro 
145                 150                 155                 160 


Gln Gly Ser Asn Met Met Phe Ala Phe Phe Ala Gln His Phe Thr His 
                165                 170                 175     


Gln Phe Phe Lys Thr Asp His Lys Arg Gly Pro Ala Phe Thr Asn Gly 
            180                 185                 190         


Leu Gly His Gly Val Asp Leu Asn His Ile Tyr Gly Glu Thr Leu Ala 
        195                 200                 205             


Arg Gln Arg Lys Leu Arg Leu Phe Lys Asp Gly Lys Met Lys Tyr Gln 
    210                 215                 220                 


Ile Ile Asp Gly Glu Met Tyr Pro Pro Thr Val Lys Asp Thr Gln Ala 
225                 230                 235                 240 


Glu Met Ile Tyr Pro Pro Gln Val Pro Glu His Leu Arg Phe Ala Val 
                245                 250                 255     


Gly Gln Glu Val Phe Gly Leu Val Pro Gly Leu Met Met Tyr Ala Thr 
            260                 265                 270         


Ile Trp Leu Arg Glu His Asn Arg Val Cys Asp Val Leu Lys Gln Glu 
        275                 280                 285             


His Pro Glu Trp Gly Asp Glu Gln Leu Phe Gln Thr Ser Arg Leu Ile 
    290                 295                 300                 


Leu Ile Gly Glu Thr Ile Lys Ile Val Ile Glu Asp Tyr Val Gln His 
305                 310                 315                 320 


Leu Ser Gly Tyr His Phe Lys Leu Lys Phe Asp Pro Glu Leu Leu Phe 
                325                 330                 335     


Asn Lys Gln Phe Gln Tyr Gln Asn Arg Ile Ala Ala Glu Phe Asn Thr 
            340                 345                 350         


Leu Tyr His Trp His Pro Leu Leu Pro Asp Thr Phe Gln Ile His Asp 
        355                 360                 365             


Gln Lys Tyr Asn Tyr Gln Gln Phe Ile Tyr Asn Asn Ser Ile Leu Leu 
    370                 375                 380                 


Glu His Gly Ile Thr Gln Phe Val Glu Ser Phe Thr Arg Gln Ile Ala 
385                 390                 395                 400 


Gly Arg Val Ala Gly Gly Arg Asn Val Pro Pro Ala Val Gln Lys Val 
                405                 410                 415     


Ser Gln Ala Ser Ile Asp Gln Ser Arg Gln Met Lys Tyr Gln Ser Phe 
            420                 425                 430         


Asn Glu Tyr Arg Lys Arg Phe Met Leu Lys Pro Tyr Glu Ser Phe Glu 
        435                 440                 445             


Glu Leu Thr Gly Glu Lys Glu Met Ser Ala Glu Leu Glu Ala Leu Tyr 
    450                 455                 460                 


Gly Asp Ile Asp Ala Val Glu Leu Tyr Pro Ala Leu Leu Val Glu Lys 
465                 470                 475                 480 


Pro Arg Pro Asp Ala Ile Phe Gly Glu Thr Met Val Glu Val Gly Ala 
                485                 490                 495     


Pro Phe Ser Leu Lys Gly Leu Met Gly Asn Val Ile Cys Ser Pro Ala 
            500                 505                 510         


Tyr Trp Lys Pro Ser Thr Phe Gly Gly Glu Val Gly Phe Gln Ile Ile 
        515                 520                 525             


Asn Thr Ala Ser Ile Gln Ser Leu Ile Cys Asn Asn Val Lys Gly Cys 
    530                 535                 540                 


Pro Phe Thr Ser Phe Ser Val Pro Asp Pro Glu Leu Ile Lys Thr Val 
545                 550                 555                 560 


Thr Ile Asn Ala Ser Ser Ser Arg Ser Gly Leu Asp Asp Ile Asn Pro 
                565                 570                 575     


Thr Val Leu Leu Lys Glu Arg Ser Thr Glu Leu 
            580                 585         


<210>  1120
<211>  674
<212>  PRT
<213>  Homo Sapiens

<400>  1120

Ala Ile Val Phe Ile Lys Gln Pro Ser Ser Gln Asp Ala Leu Gln Gly 
1               5                   10                  15      


Arg Arg Ala Leu Leu Arg Cys Glu Val Glu Ala Pro Gly Pro Val His 
            20                  25                  30          


Val Tyr Trp Leu Leu Asp Gly Ala Pro Val Gln Asp Thr Glu Arg Arg 
        35                  40                  45              


Phe Ala Gln Gly Ser Ser Leu Ser Phe Ala Ala Val Asp Arg Leu Gln 
    50                  55                  60                  


Asp Ser Gly Thr Phe Gln Cys Val Ala Arg Asp Asp Val Thr Gly Glu 
65                  70                  75                  80  


Glu Ala Arg Ser Ala Asn Ala Ser Phe Asn Ile Lys Trp Ile Glu Ala 
                85                  90                  95      


Gly Pro Val Val Leu Lys His Pro Ala Ser Glu Ala Glu Ile Gln Pro 
            100                 105                 110         


Gln Thr Gln Val Thr Leu Arg Cys His Ile Asp Gly His Pro Arg Pro 
        115                 120                 125             


Thr Tyr Gln Trp Phe Arg Asp Gly Thr Pro Leu Ser Asp Gly Gln Ser 
    130                 135                 140                 


Asn His Thr Val Ser Ser Lys Glu Arg Asn Leu Thr Leu Arg Pro Ala 
145                 150                 155                 160 


Gly Pro Glu His Ser Gly Leu Tyr Ser Cys Cys Ala His Ser Ala Phe 
                165                 170                 175     


Gly Gln Ala Cys Ser Ser Gln Asn Phe Thr Leu Ser Ile Ala Asp Glu 
            180                 185                 190         


Ser Phe Ala Arg Val Val Leu Ala Pro Gln Asp Val Val Val Ala Arg 
        195                 200                 205             


Tyr Glu Glu Ala Met Phe His Cys Gln Phe Ser Ala Gln Pro Pro Pro 
    210                 215                 220                 


Ser Leu Gln Trp Leu Phe Glu Asp Glu Thr Pro Ile Thr Asn Arg Ser 
225                 230                 235                 240 


Arg Pro Pro His Leu Arg Arg Ala Thr Val Phe Ala Asn Gly Ser Leu 
                245                 250                 255     


Leu Leu Thr Gln Val Arg Pro Arg Asn Ala Gly Ile Tyr Arg Cys Ile 
            260                 265                 270         


Gly Gln Gly Gln Arg Gly Pro Pro Ile Ile Leu Glu Ala Thr Leu His 
        275                 280                 285             


Leu Ala Glu Ile Glu Asp Met Pro Leu Phe Glu Pro Arg Val Phe Thr 
    290                 295                 300                 


Ala Gly Ser Glu Glu Arg Val Thr Cys Leu Pro Pro Lys Gly Leu Pro 
305                 310                 315                 320 


Glu Pro Ser Val Trp Trp Glu His Ala Gly Val Arg Leu Pro Thr His 
                325                 330                 335     


Gly Arg Val Tyr Gln Lys Gly His Glu Leu Val Leu Ala Asn Ile Ala 
            340                 345                 350         


Glu Ser Asp Ala Gly Val Tyr Thr Cys His Ala Ala Asn Leu Ala Gly 
        355                 360                 365             


Gln Arg Arg Gln Asp Val Asn Ile Thr Val Ala Thr Val Pro Ser Trp 
    370                 375                 380                 


Leu Lys Lys Pro Gln Asp Ser Gln Leu Glu Glu Gly Lys Pro Gly Tyr 
385                 390                 395                 400 


Leu Asp Cys Leu Thr Gln Ala Thr Pro Lys Pro Thr Val Val Trp Tyr 
                405                 410                 415     


Arg Asn Gln Met Leu Ile Ser Glu Asp Ser Arg Phe Glu Val Phe Lys 
            420                 425                 430         


Asn Gly Thr Leu Arg Ile Asn Ser Val Glu Val Tyr Asp Gly Thr Trp 
        435                 440                 445             


Tyr Arg Cys Met Ser Ser Thr Pro Ala Gly Ser Ile Glu Ala Gln Ala 
    450                 455                 460                 


Arg Val Gln Val Leu Glu Lys Leu Lys Phe Thr Pro Pro Pro Gln Pro 
465                 470                 475                 480 


Gln Gln Cys Met Glu Phe Asp Lys Glu Ala Thr Val Pro Cys Ser Ala 
                485                 490                 495     


Thr Gly Arg Glu Lys Pro Thr Ile Lys Trp Glu Arg Ala Asp Gly Ser 
            500                 505                 510         


Ser Leu Pro Glu Trp Val Thr Asp Asn Ala Gly Thr Leu His Phe Ala 
        515                 520                 525             


Arg Val Thr Arg Asp Asp Ala Gly Asn Tyr Thr Cys Ile Ala Ser Asn 
    530                 535                 540                 


Gly Pro Gln Gly Gln Ile Arg Ala His Val Gln Leu Thr Val Ala Val 
545                 550                 555                 560 


Phe Ile Thr Phe Lys Val Glu Pro Glu Arg Thr Thr Val Tyr Gln Gly 
                565                 570                 575     


His Thr Ala Leu Leu Gln Cys Glu Ala Gln Gly Asp Pro Lys Pro Leu 
            580                 585                 590         


Ile Gln Trp Lys Gly Lys Asp Arg Ile Leu Asp Pro Thr Lys Leu Gly 
        595                 600                 605             


Pro Arg Met His Ile Phe Gln Asn Gly Ser Leu Val Ile His Asp Val 
    610                 615                 620                 


Ala Pro Glu Asp Ser Gly Arg Tyr Thr Cys Ile Ala Gly Asn Ser Cys 
625                 630                 635                 640 


Asn Ile Lys His Thr Glu Ala Pro Leu Tyr Val Val Asp Lys Pro Val 
                645                 650                 655     


Pro Glu Glu Ser Glu Gly Pro Gly Ser Pro Pro Pro Tyr Lys Met Ile 
            660                 665                 670         


Gln Thr 
        


<210>  1121
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  1121

Phe His Val Gln Gln Thr Glu Met Ser Gln Thr Val Ser Thr Gly Glu 
1               5                   10                  15      


Ser Ile Ile Leu Ser Cys Ser Val Pro Asp Thr Leu Pro Asn Gly Pro 
            20                  25                  30          


Val Leu Trp Phe Lys Gly Thr Gly Pro Asn Arg Lys Leu Ile Tyr Asn 
        35                  40                  45              


Phe Lys Gln Gly Asn Phe Pro Arg Val Lys Glu Ile Gly Asp Thr Thr 
    50                  55                  60                  


Lys Pro Gly Asn Thr Asp Phe Ser Thr Arg Ile Arg Glu Ile Ser Leu 
65                  70                  75                  80  


Ala Asp Ala Gly Thr Tyr Tyr Cys Val Lys Phe Ile Lys Gly Arg Ala 
                85                  90                  95      


Ile Lys Glu Tyr Gln Ser Gly Arg Gly Thr Gln Val Phe Val Thr Glu 
            100                 105                 110         


Gln Asn Pro Arg Pro Pro Lys Asn Arg Pro Ala Gly Arg Ala Gly Ser 
        115                 120                 125             


Arg Ala His His Asp Ala His Thr Cys Leu Ser Ala Leu Pro Glu Arg 
    130                 135                 140                 


Asn Ser Thr Asn Tyr Phe Val Gln Pro Cys Cys Cys Leu Arg Leu Leu 
145                 150                 155                 160 


Gly Leu Thr Gly Leu Leu Ser Lys 
                165             


<210>  1122
<211>  1599
<212>  PRT
<213>  Homo Sapiens

<400>  1122

Glu Pro Glu Arg Cys Asn Phe Thr Leu Ala Glu Ser Lys Ala Ser Ser 
1               5                   10                  15      


His Ser Val Ser Ile Gln Trp Arg Ile Leu Gly Ser Pro Cys Asn Phe 
            20                  25                  30          


Ser Leu Ile Tyr Ser Ser Asp Thr Leu Gly Ala Ala Leu Cys Pro Thr 
        35                  40                  45              


Phe Arg Ile Asp Asn Thr Thr Tyr Gly Cys Asn Leu Gln Asp Leu Gln 
    50                  55                  60                  


Ala Gly Thr Ile Tyr Asn Phe Arg Ile Ile Ser Leu Asp Glu Glu Arg 
65                  70                  75                  80  


Thr Val Val Leu Gln Thr Asp Pro Leu Pro Pro Ala Arg Phe Gly Val 
                85                  90                  95      


Ser Lys Glu Lys Thr Thr Ser Thr Ser Leu His Val Trp Trp Thr Pro 
            100                 105                 110         


Ser Ser Gly Lys Val Thr Ser Tyr Glu Val Gln Leu Phe Asp Glu Asn 
        115                 120                 125             


Asn Gln Lys Ile Gln Gly Val Gln Ile Gln Glu Ser Thr Ser Trp Asn 
    130                 135                 140                 


Glu Tyr Thr Phe Phe Asn Leu Thr Ala Gly Ser Lys Tyr Asn Ile Ala 
145                 150                 155                 160 


Ile Thr Ala Val Ser Gly Gly Lys Arg Ser Phe Ser Val Tyr Thr Asn 
                165                 170                 175     


Gly Ser Thr Val Pro Ser Pro Val Lys Asp Ile Gly Ile Ser Thr Lys 
            180                 185                 190         


Ala Asn Ser Leu Leu Ile Ser Trp Ser His Gly Ser Gly Asn Val Glu 
        195                 200                 205             


Arg Tyr Arg Leu Met Leu Met Asp Lys Gly Ile Leu Val His Gly Gly 
    210                 215                 220                 


Val Val Asp Lys His Ala Thr Ser Tyr Ala Phe His Gly Leu Thr Pro 
225                 230                 235                 240 


Gly Tyr Leu Tyr Asn Leu Thr Val Met Thr Glu Ala Ala Gly Leu Gln 
                245                 250                 255     


Asn Tyr Arg Trp Lys Leu Val Arg Thr Ala Pro Met Glu Val Ser Asn 
            260                 265                 270         


Leu Lys Val Thr Asn Asp Gly Ser Leu Thr Ser Leu Lys Val Lys Trp 
        275                 280                 285             


Gln Arg Pro Pro Gly Asn Val Asp Ser Tyr Asn Ile Thr Leu Ser His 
    290                 295                 300                 


Lys Gly Thr Ile Lys Glu Ser Arg Val Leu Ala Pro Trp Ile Thr Glu 
305                 310                 315                 320 


Thr His Phe Lys Glu Leu Val Pro Gly Arg Leu Tyr Gln Val Thr Val 
                325                 330                 335     


Ser Cys Val Ser Gly Glu Leu Ser Ala Gln Lys Met Ala Val Gly Arg 
            340                 345                 350         


Thr Phe Pro Asp Lys Val Ala Asn Leu Glu Ala Asn Asn Asn Gly Arg 
        355                 360                 365             


Met Arg Ser Leu Val Val Ser Trp Ser Pro Pro Ala Gly Asp Trp Glu 
    370                 375                 380                 


Gln Tyr Arg Ile Leu Leu Phe Asn Asp Ser Val Val Leu Leu Asn Ile 
385                 390                 395                 400 


Thr Val Gly Lys Glu Glu Thr Gln Tyr Val Met Asp Asp Thr Gly Leu 
                405                 410                 415     


Val Pro Gly Arg Gln Tyr Glu Val Glu Val Ile Val Glu Ser Gly Asn 
            420                 425                 430         


Leu Lys Asn Ser Glu Arg Cys Gln Gly Arg Thr Val Pro Leu Ala Val 
        435                 440                 445             


Leu Gln Leu Arg Val Lys His Ala Asn Glu Thr Ser Leu Ser Ile Met 
    450                 455                 460                 


Trp Gln Thr Pro Val Ala Glu Trp Glu Lys Tyr Ile Ile Ser Leu Ala 
465                 470                 475                 480 


Asp Arg Asp Leu Leu Leu Ile His Lys Ser Leu Ser Lys Asp Ala Lys 
                485                 490                 495     


Glu Phe Thr Phe Thr Asp Leu Val Pro Gly Arg Lys Tyr Met Ala Thr 
            500                 505                 510         


Val Thr Ser Ile Ser Gly Asp Leu Lys Asn Ser Ser Ser Val Lys Gly 
        515                 520                 525             


Arg Thr Val Pro Ala Gln Val Thr Asp Leu His Val Ala Asn Gln Gly 
    530                 535                 540                 


Met Thr Ser Ser Leu Phe Thr Asn Trp Thr Gln Ala Gln Gly Asp Val 
545                 550                 555                 560 


Glu Phe Tyr Gln Val Leu Leu Ile His Glu Asn Val Val Ile Lys Asn 
                565                 570                 575     


Glu Ser Ile Ser Ser Glu Thr Ser Arg Tyr Ser Phe His Ser Leu Lys 
            580                 585                 590         


Ser Gly Ser Leu Tyr Ser Val Val Val Thr Thr Val Ser Gly Gly Ile 
        595                 600                 605             


Ser Ser Arg Gln Val Val Val Glu Gly Arg Thr Val Pro Ser Ser Val 
    610                 615                 620                 


Ser Gly Val Thr Val Asn Asn Ser Gly Arg Asn Asp Tyr Leu Ser Val 
625                 630                 635                 640 


Ser Trp Leu Leu Ala Pro Gly Asp Val Asp Asn Tyr Glu Val Thr Leu 
                645                 650                 655     


Ser His Asp Gly Lys Val Val Gln Ser Leu Val Ile Ala Lys Ser Val 
            660                 665                 670         


Arg Glu Cys Ser Phe Ser Ser Leu Thr Pro Gly Arg Leu Tyr Thr Val 
        675                 680                 685             


Thr Ile Thr Thr Arg Ser Gly Lys Tyr Glu Asn His Ser Phe Ser Gln 
    690                 695                 700                 


Glu Arg Thr Val Pro Asp Lys Val Gln Gly Val Ser Val Ser Asn Ser 
705                 710                 715                 720 


Ala Arg Ser Asp Tyr Leu Arg Val Ser Trp Val His Ala Thr Gly Asp 
                725                 730                 735     


Phe Asp His Tyr Glu Val Thr Ile Lys Asn Lys Asn Asn Phe Ile Gln 
            740                 745                 750         


Thr Lys Ser Ile Pro Lys Ser Glu Asn Glu Cys Val Phe Val Gln Leu 
        755                 760                 765             


Val Pro Gly Arg Leu Tyr Ser Val Thr Val Thr Thr Lys Ser Gly Gln 
    770                 775                 780                 


Tyr Glu Ala Asn Glu Gln Gly Asn Gly Arg Thr Ile Pro Glu Pro Val 
785                 790                 795                 800 


Lys Asp Leu Thr Leu Arg Asn Arg Ser Thr Glu Asp Leu His Val Thr 
                805                 810                 815     


Trp Ser Gly Ala Asn Gly Asp Val Asp Gln Tyr Glu Ile Gln Leu Leu 
            820                 825                 830         


Phe Asn Asp Met Lys Val Phe Pro Pro Phe His Leu Val Asn Thr Ala 
        835                 840                 845             


Thr Glu Tyr Arg Phe Thr Ser Leu Thr Pro Gly Arg Gln Tyr Lys Ile 
    850                 855                 860                 


Leu Val Leu Thr Ile Ser Gly Asp Val Gln Gln Ser Ala Phe Ile Glu 
865                 870                 875                 880 


Gly Phe Thr Val Pro Ser Ala Val Lys Asn Ile His Ile Ser Pro Asn 
                885                 890                 895     


Gly Ala Thr Asp Ser Leu Thr Val Asn Trp Thr Pro Gly Gly Gly Asp 
            900                 905                 910         


Val Asp Ser Tyr Thr Val Ser Ala Phe Arg His Ser Gln Lys Val Asp 
        915                 920                 925             


Ser Gln Thr Ile Pro Lys His Val Phe Glu His Thr Phe His Arg Leu 
    930                 935                 940                 


Glu Ala Gly Glu Gln Tyr Gln Ile Met Ile Ala Ser Val Ser Gly Ser 
945                 950                 955                 960 


Leu Lys Asn Gln Ile Asn Val Val Gly Arg Thr Val Pro Ala Ser Val 
                965                 970                 975     


Gln Gly Val Ile Ala Asp Asn Ala Tyr Ser Ser Tyr Ser Leu Ile Val 
            980                 985                 990         


Ser Trp Gln Lys Ala Ala Gly Val  Ala Glu Arg Tyr Asp  Ile Leu Leu 
        995                 1000                 1005             


Leu Thr  Glu Asn Gly Ile Leu  Leu Arg Asn Thr Ser  Glu Pro Ala 
    1010                 1015                 1020             


Thr Thr  Lys Gln His Lys Phe  Glu Asp Leu Thr Pro  Gly Lys Lys 
    1025                 1030                 1035             


Tyr Lys  Ile Gln Ile Leu Thr  Val Ser Gly Gly Leu  Phe Ser Lys 
    1040                 1045                 1050             


Glu Ala  Gln Thr Glu Gly Arg  Thr Val Pro Ala Ala  Val Thr Asp 
    1055                 1060                 1065             


Leu Arg  Ile Thr Glu Asn Ser  Thr Arg His Leu Ser  Phe Arg Trp 
    1070                 1075                 1080             


Thr Ala  Ser Glu Gly Glu Leu  Ser Trp Tyr Asn Ile  Phe Leu Tyr 
    1085                 1090                 1095             


Asn Pro  Asp Gly Asn Leu Gln  Glu Arg Ala Gln Val  Asp Pro Leu 
    1100                 1105                 1110             


Val Gln  Ser Phe Ser Phe Gln  Asn Leu Leu Gln Gly  Arg Met Tyr 
    1115                 1120                 1125             


Lys Met  Val Ile Val Thr His  Ser Gly Glu Leu Ser  Asn Glu Ser 
    1130                 1135                 1140             


Phe Ile  Phe Gly Arg Thr Val  Pro Ala Ser Val Ser  His Leu Arg 
    1145                 1150                 1155             


Gly Ser  Asn Arg Asn Thr Thr  Asp Ser Leu Trp Phe  Asn Trp Ser 
    1160                 1165                 1170             


Pro Ala  Ser Gly Asp Phe Asp  Phe Tyr Glu Leu Ile  Leu Tyr Asn 
    1175                 1180                 1185             


Pro Asn  Gly Thr Lys Lys Glu  Asn Trp Lys Asp Lys  Asp Leu Thr 
    1190                 1195                 1200             


Glu Trp  Arg Phe Gln Gly Leu  Val Pro Gly Arg Lys  Tyr Val Leu 
    1205                 1210                 1215             


Trp Val  Val Thr His Ser Gly  Asp Leu Ser Asn Lys  Val Thr Ala 
    1220                 1225                 1230             


Glu Ser  Arg Thr Ala Pro Ser  Pro Pro Ser Leu Met  Ser Phe Ala 
    1235                 1240                 1245             


Asp Ile  Ala Asn Thr Ser Leu  Ala Ile Thr Trp Lys  Gly Pro Pro 
    1250                 1255                 1260             


Asp Trp  Thr Asp Tyr Asn Asp  Phe Glu Leu Gln Trp  Leu Pro Arg 
    1265                 1270                 1275             


Asp Ala  Leu Thr Val Phe Asn  Pro Tyr Asn Asn Arg  Lys Ser Glu 
    1280                 1285                 1290             


Gly Arg  Ile Val Tyr Gly Leu  Arg Pro Gly Arg Ser  Tyr Gln Phe 
    1295                 1300                 1305             


Asn Val  Lys Thr Val Ser Gly  Asp Ser Trp Lys Thr  Tyr Ser Lys 
    1310                 1315                 1320             


Pro Ile  Phe Gly Ser Val Arg  Thr Lys Pro Asp Lys  Ile Gln Asn 
    1325                 1330                 1335             


Leu His  Cys Arg Pro Gln Asn  Ser Thr Ala Ile Ala  Cys Ser Trp 
    1340                 1345                 1350             


Ile Pro  Pro Asp Ser Asp Phe  Asp Gly Tyr Ser Ile  Glu Cys Arg 
    1355                 1360                 1365             


Lys Met  Asp Thr Gln Glu Val  Glu Phe Ser Arg Lys  Leu Glu Lys 
    1370                 1375                 1380             


Glu Lys  Ser Leu Leu Asn Ile  Met Met Leu Val Pro  His Lys Arg 
    1385                 1390                 1395             


Tyr Leu  Val Ser Ile Lys Val  Gln Ser Ala Gly Met  Thr Ser Glu 
    1400                 1405                 1410             


Val Val  Glu Asp Ser Thr Ile  Thr Met Ile Asp Arg  Pro Pro Pro 
    1415                 1420                 1425             


Pro Pro  Pro His Ile Arg Val  Asn Glu Lys Asp Val  Leu Ile Ser 
    1430                 1435                 1440             


Lys Ser  Ser Ile Asn Phe Thr  Val Asn Cys Ser Trp  Phe Ser Asp 
    1445                 1450                 1455             


Thr Asn  Gly Ala Val Lys Tyr  Phe Thr Val Val Val  Arg Glu Ala 
    1460                 1465                 1470             


Asp Gly  Ser Asp Glu Leu Lys  Pro Glu Gln Gln His  Pro Leu Pro 
    1475                 1480                 1485             


Ser Tyr  Leu Glu Tyr Arg His  Asn Ala Ser Ile Arg  Val Tyr Gln 
    1490                 1495                 1500             


Thr Asn  Tyr Phe Ala Ser Lys  Cys Ala Glu Asn Pro  Asn Ser Asn 
    1505                 1510                 1515             


Ser Lys  Ser Phe Asn Ile Lys  Leu Gly Ala Glu Met  Glu Ser Leu 
    1520                 1525                 1530             


Gly Gly  Lys Cys Asp Pro Thr  Gln Gln Lys Phe Cys  Asp Gly Pro 
    1535                 1540                 1545             


Leu Lys  Pro His Thr Ala Tyr  Arg Ile Ser Ile Arg  Ala Phe Thr 
    1550                 1555                 1560             


Gln Leu  Phe Asp Glu Asp Leu  Lys Glu Phe Thr Lys  Pro Leu Tyr 
    1565                 1570                 1575             


Ser Asp  Thr Phe Phe Ser Leu  Pro Ile Thr Thr Glu  Ser Glu Pro 
    1580                 1585                 1590             


Leu Phe  Gly Ala Ile Glu 
    1595                 


<210>  1123
<211>  552
<212>  PRT
<213>  Homo Sapiens

<400>  1123

Gln Ser Pro Thr Pro Ser Pro Thr Gly Leu Thr Thr Ala Lys Met Pro 
1               5                   10                  15      


Ser Val Pro Leu Ser Ser Asp Pro Leu Pro Thr His Thr Thr Ala Phe 
            20                  25                  30          


Ser Pro Ala Ser Thr Phe Glu Arg Glu Asn Asp Phe Ser Glu Thr Thr 
        35                  40                  45              


Thr Ser Leu Ser Pro Asp Asn Thr Ser Thr Gln Val Ser Pro Asp Ser 
    50                  55                  60                  


Leu Asp Asn Ala Ser Ala Phe Asn Thr Thr Gly Val Ser Ser Val Gln 
65                  70                  75                  80  


Thr Pro His Leu Pro Thr His Ala Asp Ser Gln Thr Pro Ser Ala Gly 
                85                  90                  95      


Thr Asp Thr Gln Thr Phe Ser Gly Ser Ala Ala Asn Ala Lys Leu Asn 
            100                 105                 110         


Pro Thr Pro Gly Ser Asn Ala Ile Ser Asp Val Pro Gly Glu Arg Ser 
        115                 120                 125             


Thr Ala Ser Thr Phe Pro Thr Asp Pro Val Ser Pro Leu Thr Thr Thr 
    130                 135                 140                 


Leu Ser Leu Ala His His Ser Ser Ala Ala Leu Pro Ala Arg Thr Ser 
145                 150                 155                 160 


Asn Thr Thr Ile Thr Ala Asn Thr Ser Asp Ala Tyr Leu Asn Ala Ser 
                165                 170                 175     


Glu Thr Thr Thr Leu Ser Pro Ser Gly Ser Ala Val Ile Ser Thr Thr 
            180                 185                 190         


Thr Ile Ala Thr Thr Pro Ser Lys Pro Thr Cys Asp Glu Lys Tyr Ala 
        195                 200                 205             


Asn Ile Thr Val Asp Tyr Leu Tyr Asn Lys Glu Thr Lys Leu Phe Thr 
    210                 215                 220                 


Ala Lys Leu Asn Val Asn Glu Asn Val Glu Cys Gly Asn Asn Thr Cys 
225                 230                 235                 240 


Thr Asn Asn Glu Val His Asn Leu Thr Glu Cys Lys Asn Ala Ser Val 
                245                 250                 255     


Ser Ile Ser His Asn Ser Cys Thr Ala Pro Asp Lys Thr Leu Ile Leu 
            260                 265                 270         


Asp Val Pro Pro Gly Val Glu Lys Phe Gln Leu His Asp Cys Thr Gln 
        275                 280                 285             


Val Glu Lys Ala Asp Thr Thr Ile Cys Leu Lys Trp Lys Asn Ile Glu 
    290                 295                 300                 


Thr Phe Thr Cys Asp Thr Gln Asn Ile Thr Tyr Arg Phe Gln Cys Gly 
305                 310                 315                 320 


Asn Met Ile Phe Asp Asn Lys Glu Ile Lys Leu Glu Asn Leu Glu Pro 
                325                 330                 335     


Glu His Glu Tyr Lys Cys Asp Ser Glu Ile Leu Tyr Asn Asn His Lys 
            340                 345                 350         


Phe Thr Asn Ala Ser Lys Ile Ile Lys Thr Asp Phe Gly Ser Pro Gly 
        355                 360                 365             


Glu Pro Gln Ile Ile Phe Cys Arg Ser Glu Ala Ala His Gln Gly Val 
    370                 375                 380                 


Ile Thr Trp Asn Pro Pro Gln Arg Ser Phe His Asn Phe Thr Leu Cys 
385                 390                 395                 400 


Tyr Ile Lys Glu Thr Glu Lys Asp Cys Leu Asn Leu Asp Lys Asn Leu 
                405                 410                 415     


Ile Lys Tyr Asp Leu Gln Asn Leu Lys Pro Tyr Thr Lys Tyr Val Leu 
            420                 425                 430         


Ser Leu His Ala Tyr Ile Ile Ala Lys Val Gln Arg Asn Gly Ser Ala 
        435                 440                 445             


Ala Met Cys His Phe Thr Thr Lys Ser Ala Pro Pro Ser Gln Val Trp 
    450                 455                 460                 


Asn Met Thr Val Ser Met Thr Ser Asp Asn Ser Met His Val Lys Cys 
465                 470                 475                 480 


Arg Pro Pro Arg Asp Arg Asn Gly Pro His Glu Arg Tyr His Leu Glu 
                485                 490                 495     


Val Glu Ala Gly Asn Thr Leu Val Arg Asn Glu Ser His Lys Asn Cys 
            500                 505                 510         


Asp Phe Arg Val Lys Asp Leu Gln Tyr Ser Thr Asp Tyr Thr Phe Lys 
        515                 520                 525             


Ala Tyr Phe His Asn Gly Asp Tyr Pro Gly Glu Pro Phe Ile Leu His 
    530                 535                 540                 


His Ser Thr Ser Tyr Asn Ser Lys 
545                 550         


<210>  1124
<211>  834
<212>  PRT
<213>  Homo Sapiens

<400>  1124

Glu Thr Pro Pro Arg Phe Thr Arg Thr Pro Val Asp Gln Thr Gly Val 
1               5                   10                  15      


Ser Gly Gly Val Ala Ser Phe Ile Cys Gln Ala Thr Gly Asp Pro Arg 
            20                  25                  30          


Pro Lys Ile Val Trp Asn Lys Lys Gly Lys Lys Val Ser Asn Gln Arg 
        35                  40                  45              


Phe Glu Val Ile Glu Phe Asp Asp Gly Ser Gly Ser Val Leu Arg Ile 
    50                  55                  60                  


Gln Pro Leu Arg Thr Pro Arg Asp Glu Ala Ile Tyr Glu Cys Val Ala 
65                  70                  75                  80  


Ser Asn Asn Val Gly Glu Ile Ser Val Ser Thr Arg Leu Thr Val Leu 
                85                  90                  95      


Arg Glu Asp Gln Ile Pro Arg Gly Phe Pro Thr Ile Asp Met Gly Pro 
            100                 105                 110         


Gln Leu Lys Val Val Glu Arg Thr Arg Thr Ala Thr Met Leu Cys Ala 
        115                 120                 125             


Ala Ser Gly Asn Pro Asp Pro Glu Ile Thr Trp Phe Lys Asp Phe Leu 
    130                 135                 140                 


Pro Val Asp Thr Ser Asn Asn Asn Gly Arg Ile Lys Gln Leu Arg Ser 
145                 150                 155                 160 


Glu Ser Ile Gly Gly Thr Pro Ile Arg Gly Ala Leu Gln Ile Glu Gln 
                165                 170                 175     


Ser Glu Glu Ser Asp Gln Gly Lys Tyr Glu Cys Val Ala Thr Asn Ser 
            180                 185                 190         


Ala Gly Thr Arg Tyr Ser Ala Pro Ala Asn Leu Tyr Val Arg Glu Leu 
        195                 200                 205             


Arg Glu Val Arg Arg Val Pro Pro Arg Phe Ser Ile Pro Pro Thr Asn 
    210                 215                 220                 


His Glu Ile Met Pro Gly Gly Ser Val Asn Ile Thr Cys Val Ala Val 
225                 230                 235                 240 


Gly Ser Pro Met Pro Tyr Val Lys Trp Met Leu Gly Ala Glu Asp Leu 
                245                 250                 255     


Thr Pro Glu Asp Asp Met Pro Ile Gly Arg Asn Val Leu Glu Leu Asn 
            260                 265                 270         


Asp Val Arg Gln Ser Ala Asn Tyr Thr Cys Val Ala Met Ser Thr Leu 
        275                 280                 285             


Gly Val Ile Glu Ala Ile Ala Gln Ile Thr Val Lys Ala Leu Pro Lys 
    290                 295                 300                 


Pro Pro Gly Thr Pro Val Val Thr Glu Ser Thr Ala Thr Ser Ile Thr 
305                 310                 315                 320 


Leu Thr Trp Asp Ser Gly Asn Pro Glu Pro Val Ser Tyr Tyr Ile Ile 
                325                 330                 335     


Gln His Lys Pro Lys Asn Ser Glu Glu Leu Tyr Lys Glu Ile Asp Gly 
            340                 345                 350         


Val Ala Thr Thr Arg Tyr Ser Val Ala Gly Leu Ser Pro Tyr Ser Asp 
        355                 360                 365             


Tyr Glu Phe Arg Val Val Ala Val Asn Asn Ile Gly Arg Gly Pro Pro 
    370                 375                 380                 


Ser Glu Pro Val Leu Thr Gln Thr Ser Glu Gln Ala Pro Ser Ser Ala 
385                 390                 395                 400 


Pro Arg Asp Val Gln Ala Arg Met Leu Ser Ser Thr Thr Ile Leu Val 
                405                 410                 415     


Gln Trp Lys Glu Pro Glu Glu Pro Asn Gly Gln Ile Gln Gly Tyr Arg 
            420                 425                 430         


Val Tyr Tyr Thr Met Asp Pro Thr Gln His Val Asn Asn Trp Met Lys 
        435                 440                 445             


His Asn Val Ala Asp Ser Gln Ile Thr Thr Ile Gly Asn Leu Val Pro 
    450                 455                 460                 


Gln Lys Thr Tyr Ser Val Lys Val Leu Ala Phe Thr Ser Ile Gly Asp 
465                 470                 475                 480 


Gly Pro Leu Ser Ser Asp Ile Gln Val Ile Thr Gln Thr Gly Val Pro 
                485                 490                 495     


Gly Gln Pro Leu Asn Phe Lys Ala Glu Pro Glu Ser Glu Thr Ser Ile 
            500                 505                 510         


Leu Leu Ser Trp Thr Pro Pro Arg Ser Asp Thr Ile Ala Asn Tyr Glu 
        515                 520                 525             


Leu Val Tyr Lys Asp Gly Glu His Gly Glu Glu Gln Arg Ile Thr Ile 
    530                 535                 540                 


Glu Pro Gly Thr Ser Tyr Arg Leu Gln Gly Leu Lys Pro Asn Ser Leu 
545                 550                 555                 560 


Tyr Tyr Phe Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu Gly Ala Ser 
                565                 570                 575     


Thr Ala Glu Ile Ser Ala Arg Thr Met Gln Ser Met Phe Ala Lys Asn 
            580                 585                 590         


Phe His Val Lys Ala Val Met Lys Thr Ser Val Leu Leu Ser Trp Glu 
        595                 600                 605             


Ile Pro Glu Asn Tyr Asn Ser Ala Met Pro Phe Lys Ile Leu Tyr Asp 
    610                 615                 620                 


Asp Gly Lys Met Val Glu Glu Val Asp Gly Arg Ala Thr Gln Lys Leu 
625                 630                 635                 640 


Ile Val Asn Leu Lys Pro Glu Lys Ser Tyr Ser Phe Val Leu Thr Asn 
                645                 650                 655     


Arg Gly Asn Ser Ala Gly Gly Leu Gln His Arg Val Thr Ala Lys Thr 
            660                 665                 670         


Ala Pro Asp Val Leu Arg Thr Lys Pro Ala Phe Ile Gly Lys Thr Asn 
        675                 680                 685             


Leu Asp Gly Met Ile Thr Val Gln Leu Pro Glu Val Pro Ala Asn Glu 
    690                 695                 700                 


Asn Ile Lys Gly Tyr Tyr Ile Ile Ile Val Pro Leu Lys Lys Ser Arg 
705                 710                 715                 720 


Gly Lys Phe Ile Lys Pro Trp Glu Ser Pro Asp Glu Met Glu Leu Asp 
                725                 730                 735     


Glu Leu Leu Lys Glu Ile Ser Arg Lys Arg Arg Ser Ile Arg Tyr Gly 
            740                 745                 750         


Arg Glu Val Glu Leu Lys Pro Tyr Ile Ala Ala His Phe Asp Val Leu 
        755                 760                 765             


Pro Thr Glu Phe Thr Leu Gly Asp Asp Lys His Tyr Gly Gly Phe Thr 
    770                 775                 780                 


Asn Lys Gln Leu Gln Ser Gly Gln Glu Tyr Val Phe Phe Val Leu Ala 
785                 790                 795                 800 


Val Met Glu His Ala Glu Ser Lys Met Tyr Ala Thr Ser Pro Tyr Ser 
                805                 810                 815     


Asp Pro Val Val Ser Met Asp Leu Asp Pro Gln Pro Ile Thr Asp Glu 
            820                 825                 830         


Glu Glu 
        


<210>  1125
<211>  1225
<212>  PRT
<213>  Homo Sapiens

<400>  1125

Asp Ser Lys Pro Val Phe Ile Lys Val Pro Glu Asp Gln Thr Gly Leu 
1               5                   10                  15      


Ser Gly Gly Val Ala Ser Phe Val Cys Gln Ala Thr Gly Glu Pro Lys 
            20                  25                  30          


Pro Arg Ile Thr Trp Met Lys Lys Gly Lys Lys Val Ser Ser Gln Arg 
        35                  40                  45              


Phe Glu Val Ile Glu Phe Asp Asp Gly Ala Gly Ser Val Leu Arg Ile 
    50                  55                  60                  


Gln Pro Leu Arg Val Gln Arg Asp Glu Ala Ile Tyr Glu Cys Thr Ala 
65                  70                  75                  80  


Thr Asn Ser Leu Gly Glu Ile Asn Thr Ser Ala Lys Leu Ser Val Leu 
                85                  90                  95      


Glu Glu Glu Gln Leu Pro Pro Gly Phe Pro Ser Ile Asp Met Gly Pro 
            100                 105                 110         


Gln Leu Lys Val Val Glu Lys Ala Arg Thr Ala Thr Met Leu Cys Ala 
        115                 120                 125             


Ala Gly Gly Asn Pro Asp Pro Glu Ile Ser Trp Phe Lys Asp Phe Leu 
    130                 135                 140                 


Pro Val Asp Pro Ala Thr Ser Asn Gly Arg Ile Lys Gln Leu Arg Ser 
145                 150                 155                 160 


Gly Ala Leu Gln Ile Glu Ser Ser Glu Glu Ser Asp Gln Gly Lys Tyr 
                165                 170                 175     


Glu Cys Val Ala Thr Asn Ser Ala Gly Thr Arg Tyr Ser Ala Pro Ala 
            180                 185                 190         


Asn Leu Tyr Val Arg Val Arg Arg Val Ala Pro Arg Phe Ser Ile Pro 
        195                 200                 205             


Pro Ser Ser Gln Glu Val Met Pro Gly Gly Ser Val Asn Leu Thr Cys 
    210                 215                 220                 


Val Ala Val Gly Ala Pro Met Pro Tyr Val Lys Trp Met Met Gly Ala 
225                 230                 235                 240 


Glu Glu Leu Thr Lys Glu Asp Glu Met Pro Val Gly Arg Asn Val Leu 
                245                 250                 255     


Glu Leu Ser Asn Val Val Arg Ser Ala Asn Tyr Thr Cys Val Ala Ile 
            260                 265                 270         


Ser Ser Leu Gly Met Ile Glu Ala Thr Ala Gln Val Thr Val Lys Ala 
        275                 280                 285             


Leu Pro Lys Pro Pro Ile Asp Leu Val Val Thr Glu Thr Thr Ala Thr 
    290                 295                 300                 


Ser Val Thr Leu Thr Trp Asp Ser Gly Asn Ser Glu Pro Val Thr Tyr 
305                 310                 315                 320 


Tyr Gly Ile Gln Tyr Arg Ala Ala Gly Thr Glu Gly Pro Phe Gln Glu 
                325                 330                 335     


Val Asp Gly Val Ala Thr Thr Arg Tyr Ser Ile Gly Gly Leu Ser Pro 
            340                 345                 350         


Phe Ser Glu Tyr Ala Phe Arg Val Leu Ala Val Asn Ser Ile Gly Arg 
        355                 360                 365             


Gly Pro Pro Ser Glu Ala Val Arg Ala Arg Thr Gly Glu Gln Ala Pro 
    370                 375                 380                 


Ser Ser Pro Pro Arg Arg Val Gln Ala Arg Met Leu Ser Ala Ser Thr 
385                 390                 395                 400 


Met Leu Val Gln Trp Glu Pro Pro Glu Glu Pro Asn Gly Leu Val Arg 
                405                 410                 415     


Gly Tyr Arg Val Tyr Tyr Thr Pro Asp Ser Arg Arg Pro Pro Asn Ala 
            420                 425                 430         


Trp His Lys His Asn Thr Asp Ala Gly Leu Leu Thr Thr Val Gly Ser 
        435                 440                 445             


Leu Leu Pro Gly Ile Thr Tyr Ser Leu Arg Val Leu Ala Phe Thr Ala 
    450                 455                 460                 


Val Gly Asp Gly Pro Pro Ser Pro Thr Ile Gln Val Lys Thr Gln Gln 
465                 470                 475                 480 


Gly Val Pro Ala Gln Pro Ala Asp Phe Gln Ala Glu Val Glu Ser Asp 
                485                 490                 495     


Thr Arg Ile Gln Leu Ser Trp Leu Leu Pro Pro Gln Glu Arg Ile Ile 
            500                 505                 510         


Met Tyr Glu Leu Val Tyr Trp Ala Ala Glu Asp Glu Asp Gln Gln His 
        515                 520                 525             


Lys Val Thr Phe Asp Pro Thr Ser Ser Tyr Thr Leu Glu Asp Leu Lys 
    530                 535                 540                 


Pro Asp Thr Leu Tyr Arg Phe Gln Leu Ala Ala Arg Ser Asp Met Gly 
545                 550                 555                 560 


Val Gly Val Phe Thr Pro Thr Ile Glu Ala Arg Thr Ala Gln Ser Thr 
                565                 570                 575     


Pro Ser Ala Pro Pro Gln Lys Val Met Cys Val Ser Met Gly Ser Thr 
            580                 585                 590         


Thr Val Arg Val Ser Trp Val Pro Pro Pro Ala Asp Ser Arg Asn Gly 
        595                 600                 605             


Val Ile Thr Gln Tyr Ser Val Ala Tyr Glu Ala Val Asp Gly Glu Asp 
    610                 615                 620                 


Arg Gly Arg His Val Val Asp Gly Ile Ser Arg Glu His Ser Ser Trp 
625                 630                 635                 640 


Asp Leu Val Gly Leu Glu Lys Trp Thr Glu Tyr Arg Val Trp Val Arg 
                645                 650                 655     


Ala His Thr Asp Val Gly Pro Gly Pro Glu Ser Ser Pro Val Leu Val 
            660                 665                 670         


Arg Thr Asp Glu Asp Val Pro Ser Gly Pro Pro Arg Lys Val Glu Val 
        675                 680                 685             


Glu Pro Leu Asn Ser Thr Ala Val His Val Tyr Trp Lys Leu Pro Val 
    690                 695                 700                 


Pro Ser Lys Gln His Gly Gln Ile Arg Gly Tyr Gln Val Thr Tyr Val 
705                 710                 715                 720 


Arg Leu Glu Asn Gly Glu Pro Arg Gly Leu Pro Ile Ile Gln Asp Val 
                725                 730                 735     


Met Leu Ala Glu Ala Gln Glu Thr Thr Ile Ser Gly Leu Thr Pro Glu 
            740                 745                 750         


Thr Thr Tyr Ser Val Thr Val Ala Ala Tyr Thr Thr Lys Gly Asp Gly 
        755                 760                 765             


Ala Arg Ser Lys Pro Lys Ile Val Thr Thr Thr Gly Ala Val Pro Gly 
    770                 775                 780                 


Arg Pro Thr Met Met Ile Ser Thr Thr Ala Met Asn Thr Ala Leu Leu 
785                 790                 795                 800 


Gln Trp His Pro Pro Lys Glu Leu Pro Gly Glu Leu Leu Gly Tyr Arg 
                805                 810                 815     


Leu Gln Tyr Cys Arg Ala Asp Glu Ala Arg Pro Asn Thr Ile Asp Phe 
            820                 825                 830         


Gly Lys Asp Asp Gln His Phe Thr Val Thr Gly Leu His Lys Gly Thr 
        835                 840                 845             


Thr Tyr Ile Phe Arg Leu Ala Ala Lys Asn Arg Ala Gly Leu Gly Glu 
    850                 855                 860                 


Glu Phe Glu Lys Glu Ile Arg Thr Pro Glu Asp Leu Pro Ser Gly Phe 
865                 870                 875                 880 


Pro Gln Asn Leu His Val Thr Gly Leu Thr Thr Ser Thr Thr Glu Leu 
                885                 890                 895     


Ala Trp Asp Pro Pro Val Leu Ala Glu Arg Asn Gly Arg Ile Ile Ser 
            900                 905                 910         


Tyr Thr Val Val Phe Arg Asp Ile Asn Ser Gln Gln Glu Leu Gln Asn 
        915                 920                 925             


Ile Thr Thr Asp Thr Arg Phe Thr Leu Thr Gly Leu Lys Pro Asp Thr 
    930                 935                 940                 


Thr Tyr Asp Ile Lys Val Arg Ala Trp Thr Ser Lys Gly Ser Gly Pro 
945                 950                 955                 960 


Leu Ser Pro Ser Ile Gln Ser Arg Thr Met Pro Val Glu Gln Val Phe 
                965                 970                 975     


Ala Lys Asn Phe Arg Val Ala Ala Ala Met Lys Thr Ser Val Leu Leu 
            980                 985                 990         


Ser Trp Glu Val Pro Asp Ser Tyr  Lys Ser Ala Val Pro  Phe Lys Ile 
        995                 1000                 1005             


Leu Tyr  Asn Gly Gln Ser Val  Glu Val Asp Gly His  Ser Met Arg 
    1010                 1015                 1020             


Lys Leu  Ile Ala Asp Leu Gln  Pro Asn Thr Glu Tyr  Ser Phe Val 
    1025                 1030                 1035             


Leu Met  Asn Arg Gly Ser Ser  Ala Gly Gly Leu Gln  His Leu Val 
    1040                 1045                 1050             


Ser Ile  Arg Thr Ala Pro Asp  Leu Leu Pro His Lys  Pro Leu Pro 
    1055                 1060                 1065             


Ala Ser  Ala Tyr Ile Glu Asp  Gly Arg Phe Asp Leu  Ser Met Pro 
    1070                 1075                 1080             


His Val  Gln Asp Pro Ser Leu  Val Arg Trp Phe Tyr  Ile Val Val 
    1085                 1090                 1095             


Val Pro  Ile Asp Arg Val Gly  Gly Ser Met Leu Thr  Pro Arg Trp 
    1100                 1105                 1110             


Ser Thr  Pro Glu Glu Leu Glu  Leu Asp Glu Leu Leu  Glu Ala Ile 
    1115                 1120                 1125             


Glu Gln  Gly Gly Glu Glu Gln  Arg Arg Arg Arg Arg  Gln Ala Glu 
    1130                 1135                 1140             


Arg Leu  Lys Pro Tyr Val Ala  Ala Gln Leu Asp Val  Leu Pro Glu 
    1145                 1150                 1155             


Thr Phe  Thr Leu Gly Asp Lys  Lys Asn Tyr Arg Gly  Phe Tyr Asn 
    1160                 1165                 1170             


Arg Pro  Leu Ser Pro Asp Leu  Ser Tyr Gln Cys Phe  Val Leu Ala 
    1175                 1180                 1185             


Ser Leu  Lys Glu Pro Met Asp  Gln Lys Arg Tyr Ala  Ser Ser Pro 
    1190                 1195                 1200             


Tyr Ser  Asp Glu Ile Val Val  Gln Val Thr Pro Ala  Gln Gln Gln 
    1205                 1210                 1215             


Glu Glu  Pro Glu Met Leu Trp  
    1220                 1225 


<210>  1126
<211>  717
<212>  PRT
<213>  Homo Sapiens

<400>  1126

Val Leu His Tyr Val Val Cys Phe Pro Ala Leu Thr Glu Gly Tyr Val 
1               5                   10                  15      


Gly Ala Leu His Glu Asn Arg His Gly Ser Ala Val Gln Ile Arg Arg 
            20                  25                  30          


Arg Lys Ala Ser Gly Asp Pro Tyr Trp Ala Tyr Ser Gly Ala Tyr Gly 
        35                  40                  45              


Pro Glu His Trp Val Thr Ser Ser Val Ser Cys Gly Gly Arg His Gln 
    50                  55                  60                  


Ser Pro Ile Asp Ile Leu Asp Gln His Ala Arg Val Gly Glu Glu Tyr 
65                  70                  75                  80  


Gln Glu Leu Gln Leu Asp Gly Phe Asp Asn Glu Ser Ser Asn Lys Thr 
                85                  90                  95      


Trp Met Lys Asn Thr Gly Lys Thr Val Ala Ile Leu Leu Lys Asp Asp 
            100                 105                 110         


Tyr Phe Val Ser Gly Ala Gly Leu Pro Gly Arg Phe Lys Ala Glu Lys 
        115                 120                 125             


Val Glu Phe His Trp Gly His Ser Asn Gly Ser Ala Gly Ser Glu His 
    130                 135                 140                 


Ser Ile Asn Gly Arg Arg Phe Pro Val Glu Met Gln Ile Phe Phe Tyr 
145                 150                 155                 160 


Asn Pro Asp Asp Phe Asp Ser Phe Gln Thr Ala Ile Ser Glu Asn Arg 
                165                 170                 175     


Ile Ile Gly Ala Met Ala Ile Phe Phe Gln Val Ser Pro Arg Asp Asn 
            180                 185                 190         


Ser Ala Leu Asp Pro Ile Ile His Gly Leu Lys Gly Val Val His His 
        195                 200                 205             


Glu Lys Glu Thr Phe Leu Asp Pro Phe Val Leu Arg Asp Leu Leu Pro 
    210                 215                 220                 


Ala Ser Leu Gly Ser Tyr Tyr Arg Tyr Thr Gly Ser Leu Thr Thr Pro 
225                 230                 235                 240 


Pro Cys Ser Glu Ile Val Glu Trp Ile Val Phe Arg Arg Pro Val Pro 
                245                 250                 255     


Ile Ser Tyr His Gln Leu Glu Ala Phe Tyr Ser Ile Phe Thr Thr Glu 
            260                 265                 270         


Gln Gln Asp His Val Lys Ser Val Glu Tyr Leu Arg Asn Asn Phe Arg 
        275                 280                 285             


Pro Gln Gln Arg Leu His Asp Arg Val Val Ser Lys Ser Ala Val Arg 
    290                 295                 300                 


Asp Ser Trp Asn His Asp Met Thr Asp Phe Leu Glu Asn Pro Leu Gly 
305                 310                 315                 320 


Thr Glu Ala Ser Lys Val Cys Ser Ser Pro Pro Ile His Met Lys Val 
                325                 330                 335     


Gln Pro Leu Asn Gln Thr Ala Leu Gln Val Ser Trp Ser Gln Pro Glu 
            340                 345                 350         


Thr Ile Tyr His Pro Pro Ile Met Asn Tyr Met Ile Ser Tyr Ser Trp 
        355                 360                 365             


Thr Lys Asn Glu Asp Glu Lys Glu Lys Thr Phe Thr Lys Asp Ser Asp 
    370                 375                 380                 


Lys Asp Leu Lys Ala Thr Ile Ser His Val Ser Pro Asp Ser Leu Tyr 
385                 390                 395                 400 


Leu Phe Arg Val Gln Ala Val Cys Arg Asn Asp Met Arg Ser Asp Phe 
                405                 410                 415     


Ser Gln Thr Met Leu Phe Gln Ala Asn Thr Thr Arg Ile Phe Gln Gly 
            420                 425                 430         


Thr Arg Ile Val Lys Thr Gly Val Pro Thr Ala Ser Pro Ala Ser Ser 
        435                 440                 445             


Ala Asp Met Ala Pro Ile Ser Ser Gly Ser Ser Thr Trp Thr Ser Ser 
    450                 455                 460                 


Gly Ile Pro Phe Ser Phe Val Ser Met Ala Thr Gly Met Gly Pro Ser 
465                 470                 475                 480 


Ser Ser Gly Ser Gln Ala Thr Val Ala Ser Val Val Thr Ser Thr Leu 
                485                 490                 495     


Leu Ala Gly Leu Gly Phe Gly Gly Gly Gly Ile Ser Ser Phe Pro Ser 
            500                 505                 510         


Thr Val Trp Pro Thr Arg Leu Pro Thr Ala Ala Ser Ala Ser Lys Gln 
        515                 520                 525             


Ala Ala Arg Pro Val Leu Ala Thr Thr Glu Ala Leu Ala Ser Pro Gly 
    530                 535                 540                 


Pro Asp Gly Asp Ser Ser Pro Thr Lys Asp Gly Glu Gly Thr Glu Glu 
545                 550                 555                 560 


Gly Glu Lys Asp Glu Lys Ser Glu Ser Glu Asp Gly Glu Arg Glu His 
                565                 570                 575     


Glu Glu Asp Gly Glu Lys Asp Ser Glu Lys Lys Glu Lys Ser Gly Val 
            580                 585                 590         


Thr His Ala Ala Glu Glu Arg Asn Gln Thr Glu Pro Ser Pro Thr Pro 
        595                 600                 605             


Ser Ser Pro Asn Arg Thr Ala Glu Gly Gly His Gln Thr Ile Pro Gly 
    610                 615                 620                 


His Glu Gln Asp His Thr Ala Val Pro Thr Asp Gln Thr Gly Gly Arg 
625                 630                 635                 640 


Arg Asp Ala Gly Pro Gly Leu Asp Pro Asp Met Val Thr Ser Thr Gln 
                645                 650                 655     


Val Pro Pro Thr Ala Thr Glu Glu Gln Tyr Ala Gly Ser Asp Pro Lys 
            660                 665                 670         


Arg Pro Glu Met Pro Ser Lys Lys Pro Met Ser Arg Gly Asp Arg Phe 
        675                 680                 685             


Ser Glu Asp Ser Arg Phe Ile Thr Val Asn Pro Ala Glu Lys Asn Thr 
    690                 695                 700                 


Ser Gly Met Ile Ser Arg Pro Ala Pro Gly Arg Met Glu 
705                 710                 715         


<210>  1127
<211>  727
<212>  PRT
<213>  Homo Sapiens

<400>  1127

Pro Ala Pro Asn Pro Gly Arg Asn Leu Thr Val Glu Thr Gln Thr Thr 
1               5                   10                  15      


Ser Ser Ile Ser Leu Ser Trp Glu Val Pro Asp Gly Leu Asp Ser Gln 
            20                  25                  30          


Asn Ser Asn Tyr Trp Val Gln Cys Thr Gly Asp Gly Gly Thr Thr Glu 
        35                  40                  45              


Thr Arg Asn Thr Thr Ala Thr Asn Val Thr Val Asp Gly Leu Gly Pro 
    50                  55                  60                  


Gly Ser Leu Tyr Thr Cys Ser Val Trp Val Glu Lys Asp Gly Val Asn 
65                  70                  75                  80  


Ser Ser Val Gly Thr Val Thr Thr Ala Thr Ala Pro Asn Pro Val Arg 
                85                  90                  95      


Asn Leu Arg Val Glu Ala Gln Thr Asn Ser Ser Ile Ala Leu Thr Trp 
            100                 105                 110         


Glu Val Pro Asp Gly Pro Asp Pro Gln Asn Ser Thr Tyr Gly Val Glu 
        115                 120                 125             


Tyr Thr Gly Asp Gly Gly Arg Ala Gly Thr Arg Ser Thr Ala His Thr 
    130                 135                 140                 


Asn Ile Thr Val Asp Gly Leu Glu Pro Gly Cys Leu Tyr Ala Phe Ser 
145                 150                 155                 160 


Met Trp Val Gly Lys Asn Gly Ile Asn Ser Ser Arg Glu Thr Arg Asn 
                165                 170                 175     


Ala Thr Thr Ala His Asn Pro Val Arg Asn Leu Arg Val Glu Ala Gln 
            180                 185                 190         


Thr Thr Ser Ser Ile Ser Leu Ser Trp Glu Val Pro Asp Gly Thr Asp 
        195                 200                 205             


Pro Gln Asn Ser Thr Tyr Cys Val Gln Cys Thr Gly Asp Gly Gly Arg 
    210                 215                 220                 


Thr Glu Thr Arg Asn Thr Thr Asp Thr Arg Val Thr Val Asp Gly Leu 
225                 230                 235                 240 


Gly Pro Gly Ser Leu Tyr Thr Cys Ser Val Trp Val Glu Lys Asp Gly 
                245                 250                 255     


Val Asn Ser Ser Val Glu Ile Val Thr Ser Ala Thr Ala Pro Asn Pro 
            260                 265                 270         


Val Arg Asn Leu Thr Val Glu Ala Gln Thr Asn Ser Ser Ile Ala Leu 
        275                 280                 285             


Thr Trp Glu Val Pro Asp Gly Pro Asp Pro Gln Asn Ser Thr Tyr Gly 
    290                 295                 300                 


Val Glu Tyr Thr Gly Asp Gly Gly Arg Ala Gly Thr Arg Ser Thr Ala 
305                 310                 315                 320 


Tyr Thr Asn Ile Thr Val Asp Arg Leu Glu Pro Gly Cys Leu Tyr Val 
                325                 330                 335     


Phe Ser Val Trp Val Gly Lys Asn Gly Ile Asn Ser Ser Arg Glu Thr 
            340                 345                 350         


Arg Asn Ala Thr Thr Ala Pro Asn Pro Val Arg Asn Leu His Met Glu 
        355                 360                 365             


Thr Gln Thr Asn Ser Ser Ile Ala Leu Cys Trp Glu Val Pro Asp Gly 
    370                 375                 380                 


Pro Tyr Pro Gln Asp Tyr Thr Tyr Trp Val Glu Tyr Thr Gly Asp Gly 
385                 390                 395                 400 


Gly Gly Thr Glu Thr Arg Asn Thr Thr Asn Thr Ser Val Thr Ala Glu 
                405                 410                 415     


Arg Leu Glu Pro Gly Thr Leu Tyr Thr Phe Ser Val Trp Ala Glu Lys 
            420                 425                 430         


Asn Gly Ala Arg Gly Ser Arg Gln Asn Val Ser Ile Ser Thr Val Pro 
        435                 440                 445             


Asn Ala Val Thr Ser Leu Ser Lys Gln Asp Trp Thr Asn Ser Thr Ile 
    450                 455                 460                 


Ala Leu Arg Trp Thr Ala Pro Gln Gly Pro Gly Gln Ser Ser Tyr Ser 
465                 470                 475                 480 


Tyr Trp Val Ser Trp Val Arg Glu Gly Met Thr Asp Pro Arg Thr Gln 
                485                 490                 495     


Ser Thr Ser Gly Thr Asp Ile Thr Leu Lys Glu Leu Glu Ala Gly Ser 
            500                 505                 510         


Leu Tyr His Leu Thr Val Trp Ala Glu Arg Asn Glu Val Arg Gly Tyr 
        515                 520                 525             


Asn Ser Thr Leu Thr Ala Ala Thr Ala Pro Asn Glu Val Thr Asp Leu 
    530                 535                 540                 


Gln Asn Glu Thr Gln Thr Lys Asn Ser Val Met Leu Trp Trp Lys Ala 
545                 550                 555                 560 


Pro Gly Asp Pro His Ser Gln Leu Tyr Val Tyr Trp Val Gln Trp Ala 
                565                 570                 575     


Ser Lys Gly His Pro Arg Arg Gly Gln Asp Pro Gln Ala Asn Trp Val 
            580                 585                 590         


Asn Gln Thr Ser Arg Thr Asn Glu Thr Trp Tyr Lys Val Glu Ala Leu 
        595                 600                 605             


Glu Pro Gly Thr Leu Tyr Asn Phe Thr Val Trp Ala Glu Arg Asn Asp 
    610                 615                 620                 


Val Ala Ser Ser Thr Gln Ser Leu Cys Ala Ser Thr Tyr Pro Asp Thr 
625                 630                 635                 640 


Val Thr Ile Thr Ser Cys Val Ser Thr Ser Ala Gly Tyr Gly Val Asn 
                645                 650                 655     


Leu Ile Trp Ser Cys Pro Gln Gly Gly Tyr Glu Ala Phe Glu Leu Glu 
            660                 665                 670         


Val Gly Gly Gln Arg Gly Ser Gln Asp Arg Ser Ser Cys Gly Glu Ala 
        675                 680                 685             


Val Ser Val Leu Gly Leu Gly Pro Ala Arg Ser Tyr Pro Ala Thr Ile 
    690                 695                 700                 


Thr Thr Ile Trp Asp Gly Met Lys Val Val Ser His Ser Val Val Cys 
705                 710                 715                 720 


His Thr Glu Ser Ala Gly Val 
                725         


<210>  1128
<211>  504
<212>  PRT
<213>  Homo Sapiens

<400>  1128

Ala Gly Gly Thr Pro Ser Pro Ile Pro Asp Pro Ser Val Ala Thr Val 
1               5                   10                  15      


Ala Thr Gly Glu Asn Gly Ile Thr Gln Ile Ser Ser Thr Ala Glu Ser 
            20                  25                  30          


Phe His Lys Gln Asn Gly Thr Gly Thr Pro Gln Val Glu Thr Asn Thr 
        35                  40                  45              


Ser Glu Asp Gly Glu Ser Ser Gly Ala Asn Asp Ser Leu Arg Thr Pro 
    50                  55                  60                  


Glu Gln Gly Ser Asn Gly Thr Asp Gly Ala Ser Gln Lys Thr Pro Ser 
65                  70                  75                  80  


Ser Thr Gly Pro Ser Pro Val Phe Asp Ile Lys Ala Val Ser Ile Ser 
                85                  90                  95      


Pro Thr Asn Val Ile Leu Thr Trp Lys Ser Asn Asp Thr Ala Ala Ser 
            100                 105                 110         


Glu Tyr Lys Tyr Val Val Lys His Lys Met Glu Asn Glu Lys Thr Ile 
        115                 120                 125             


Thr Val Val His Gln Pro Trp Cys Asn Ile Thr Gly Leu Arg Pro Ala 
    130                 135                 140                 


Thr Ser Tyr Val Phe Ser Ile Thr Pro Gly Ile Gly Asn Glu Thr Trp 
145                 150                 155                 160 


Gly Asp Pro Arg Val Ile Lys Val Ile Thr Glu Pro Ile Pro Val Ser 
                165                 170                 175     


Asp Leu Arg Val Ala Leu Thr Gly Val Arg Lys Ala Ala Leu Ser Trp 
            180                 185                 190         


Ser Asn Gly Asn Gly Thr Ala Ser Cys Arg Val Leu Leu Glu Ser Ile 
        195                 200                 205             


Gly Ser His Glu Glu Leu Thr Gln Asp Ser Arg Leu Gln Val Asn Ile 
    210                 215                 220                 


Ser Gly Leu Lys Pro Gly Val Gln Tyr Asn Ile Asn Pro Tyr Leu Leu 
225                 230                 235                 240 


Gln Ser Asn Lys Thr Lys Gly Asp Pro Leu Gly Thr Glu Gly Gly Leu 
                245                 250                 255     


Asp Ala Ser Asn Thr Glu Arg Ser Arg Ala Gly Ser Pro Thr Ala Pro 
            260                 265                 270         


Val His Asp Glu Ser Leu Val Gly Pro Val Asp Pro Ser Ser Gly Gln 
        275                 280                 285             


Gln Ser Arg Asp Thr Glu Val Leu Leu Val Gly Leu Glu Pro Gly Thr 
    290                 295                 300                 


Arg Tyr Asn Ala Thr Val Tyr Ser Gln Ala Ala Asn Gly Thr Glu Gly 
305                 310                 315                 320 


Gln Pro Gln Ala Ile Glu Phe Arg Thr Asn Ala Ile Gln Val Phe Asp 
                325                 330                 335     


Val Thr Ala Val Asn Ile Ser Ala Thr Ser Leu Thr Leu Ile Trp Lys 
            340                 345                 350         


Val Ser Asp Asn Glu Ser Ser Ser Asn Tyr Thr Tyr Lys Ile His Val 
        355                 360                 365             


Ala Gly Glu Thr Asp Ser Ser Asn Leu Asn Val Ser Glu Pro Arg Ala 
    370                 375                 380                 


Val Ile Pro Gly Leu Arg Ser Ser Thr Phe Tyr Asn Ile Thr Val Cys 
385                 390                 395                 400 


Pro Val Leu Gly Asp Ile Glu Gly Thr Pro Gly Phe Leu Gln Val His 
                405                 410                 415     


Thr Pro Pro Val Pro Val Ser Asp Phe Arg Val Thr Val Val Ser Thr 
            420                 425                 430         


Thr Glu Ile Gly Leu Ala Trp Ser Ser His Asp Ala Glu Ser Phe Gln 
        435                 440                 445             


Met His Ile Thr Gln Glu Gly Ala Gly Asn Ser Arg Val Glu Ile Thr 
    450                 455                 460                 


Thr Asn Gln Ser Ile Ile Ile Gly Gly Leu Phe Pro Gly Thr Lys Tyr 
465                 470                 475                 480 


Cys Phe Glu Ile Val Pro Lys Gly Pro Asn Gly Thr Glu Gly Ala Ser 
                485                 490                 495     


Arg Thr Val Cys Asn Arg Thr Gly 
            500                 


<210>  1129
<211>  727
<212>  PRT
<213>  Homo Sapiens

<400>  1129

Ala Gln Gly Gln Phe Ser Ala Gly Gly Cys Thr Phe Asp Asp Gly Pro 
1               5                   10                  15      


Gly Ala Cys Asp Tyr His Gln Asp Leu Tyr Asp Asp Phe Glu Trp Val 
            20                  25                  30          


His Val Ser Ala Gln Glu Pro His Tyr Leu Pro Pro Glu Met Pro Gln 
        35                  40                  45              


Gly Ser Tyr Met Ile Val Asp Ser Ser Asp His Asp Pro Gly Glu Lys 
    50                  55                  60                  


Ala Arg Leu Gln Leu Pro Thr Met Lys Glu Asn Asp Thr His Cys Ile 
65                  70                  75                  80  


Asp Phe Ser Tyr Leu Leu Tyr Ser Gln Lys Gly Leu Asn Pro Gly Thr 
                85                  90                  95      


Leu Asn Ile Leu Val Arg Val Asn Lys Gly Pro Leu Ala Asn Pro Ile 
            100                 105                 110         


Trp Asn Val Thr Gly Phe Thr Gly Arg Asp Trp Leu Arg Ala Glu Leu 
        115                 120                 125             


Ala Val Ser Thr Phe Trp Pro Asn Glu Tyr Gln Val Ile Phe Glu Ala 
    130                 135                 140                 


Glu Val Ser Gly Gly Arg Ser Gly Tyr Ile Ala Ile Asp Asp Ile Gln 
145                 150                 155                 160 


Val Leu Ser Tyr Pro Cys Asp Lys Ser Pro His Phe Leu Arg Leu Gly 
                165                 170                 175     


Asp Val Glu Val Asn Ala Gly Gln Asn Ala Thr Phe Gln Cys Ile Ala 
            180                 185                 190         


Thr Gly Arg Asp Ala Val His Asn Lys Leu Trp Leu Gln Arg Arg Asn 
        195                 200                 205             


Gly Glu Asp Ile Pro Val Ala Gln Thr Lys Asn Ile Asn His Arg Arg 
    210                 215                 220                 


Phe Ala Ala Ser Phe Arg Leu Gln Glu Val Thr Lys Thr Asp Gln Asp 
225                 230                 235                 240 


Leu Tyr Arg Cys Val Thr Gln Ser Glu Arg Gly Ser Gly Val Ser Asn 
                245                 250                 255     


Phe Ala Gln Leu Ile Val Arg Glu Pro Pro Arg Pro Ile Ala Pro Pro 
            260                 265                 270         


Gln Leu Leu Gly Val Gly Pro Thr Tyr Leu Leu Ile Gln Leu Asn Ala 
        275                 280                 285             


Asn Ser Ile Ile Gly Asp Gly Pro Ile Ile Leu Lys Glu Val Glu Tyr 
    290                 295                 300                 


Arg Met Thr Ser Gly Ser Trp Thr Glu Thr His Ala Val Asn Ala Pro 
305                 310                 315                 320 


Thr Tyr Lys Leu Trp His Leu Asp Pro Asp Thr Glu Tyr Glu Ile Arg 
                325                 330                 335     


Val Leu Leu Thr Arg Pro Gly Glu Gly Gly Thr Gly Leu Pro Gly Pro 
            340                 345                 350         


Pro Leu Ile Thr Arg Thr Lys Cys Ala Glu Pro Met Arg Thr Pro Lys 
        355                 360                 365             


Thr Leu Lys Ile Ala Glu Ile Gln Ala Arg Arg Ile Ala Val Asp Trp 
    370                 375                 380                 


Glu Ser Leu Gly Tyr Asn Ile Thr Arg Cys His Thr Phe Asn Val Thr 
385                 390                 395                 400 


Ile Cys Tyr His Tyr Phe Arg Gly His Asn Glu Ser Lys Ala Asp Cys 
                405                 410                 415     


Leu Asp Met Asp Pro Lys Ala Pro Gln His Val Val Asn His Leu Pro 
            420                 425                 430         


Pro Tyr Thr Asn Val Ser Leu Lys Met Ile Leu Thr Asn Pro Glu Gly 
        435                 440                 445             


Arg Lys Glu Ser Glu Glu Thr Ile Ile Gln Thr Asp Glu Asp Val Pro 
    450                 455                 460                 


Gly Pro Val Pro Val Lys Ser Leu Gln Gly Thr Ser Phe Glu Asn Lys 
465                 470                 475                 480 


Ile Phe Leu Asn Trp Lys Glu Pro Leu Asp Pro Asn Gly Ile Ile Thr 
                485                 490                 495     


Gln Tyr Glu Ile Ser Tyr Ser Ser Ile Arg Ser Phe Asp Pro Ala Val 
            500                 505                 510         


Pro Val Ala Gly Pro Pro Gln Thr Val Ser Asn Leu Trp Asn Ser Thr 
        515                 520                 525             


His His Val Phe Met His Leu His Pro Gly Thr Thr Tyr Gln Phe Phe 
    530                 535                 540                 


Ile Arg Ala Ser Thr Val Lys Gly Phe Gly Pro Ala Thr Ala Ile Asn 
545                 550                 555                 560 


Val Thr Thr Asn Ile Ser Ala Pro Thr Leu Pro Asp Tyr Glu Gly Val 
                565                 570                 575     


Asp Ala Ser Leu Asn Glu Thr Ala Thr Thr Ile Thr Val Leu Leu Arg 
            580                 585                 590         


Pro Ala Gln Ala Lys Gly Ala Pro Ile Ser Ala Tyr Gln Ile Val Val 
        595                 600                 605             


Glu Glu Leu His Pro His Arg Thr Lys Arg Glu Ala Gly Ala Met Glu 
    610                 615                 620                 


Cys Tyr Gln Val Pro Val Thr Tyr Gln Asn Ala Met Ser Gly Gly Ala 
625                 630                 635                 640 


Pro Tyr Tyr Phe Ala Ala Glu Leu Pro Pro Gly Asn Leu Pro Glu Pro 
                645                 650                 655     


Ala Pro Phe Thr Val Gly Asp Asn Arg Thr Tyr Gln Gly Phe Trp Asn 
            660                 665                 670         


Pro Pro Leu Ala Pro Arg Lys Gly Tyr Asn Ile Tyr Phe Gln Ala Met 
        675                 680                 685             


Ser Ser Val Glu Lys Glu Thr Lys Thr Gln Cys Val Arg Ile Ala Thr 
    690                 695                 700                 


Lys Ala Ala Ala Thr Glu Glu Pro Glu Val Ile Pro Asp Pro Ala Lys 
705                 710                 715                 720 


Gln Thr Asp Arg Val Val Lys 
                725         


<210>  1130
<211>  512
<212>  PRT
<213>  Homo Sapiens

<400>  1130

Val Ser Ala His Gly Cys Leu Phe Asp Arg Arg Leu Cys Ser His Leu 
1               5                   10                  15      


Glu Val Cys Ile Gln Asp Gly Leu Phe Gly Gln Cys Gln Val Gly Val 
            20                  25                  30          


Gly Gln Ala Arg Pro Leu Leu Gln Val Thr Ser Pro Val Leu Gln Arg 
        35                  40                  45              


Leu Gln Gly Val Leu Arg Gln Leu Met Ser Gln Gly Leu Ser Trp His 
    50                  55                  60                  


Asp Asp Leu Thr Gln Tyr Val Ile Ser Gln Glu Met Glu Arg Ile Pro 
65                  70                  75                  80  


Arg Leu Arg Pro Pro Glu Pro Arg Pro Arg Asp Arg Ser Gly Leu Ala 
                85                  90                  95      


Pro Lys Arg Pro Gly Pro Ala Gly Glu Leu Leu Leu Gln Asp Ile Pro 
            100                 105                 110         


Thr Gly Ser Ala Pro Ala Ala Gln His Arg Leu Pro Gln Pro Pro Val 
        115                 120                 125             


Gly Lys Gly Gly Ala Gly Ala Ser Ser Ser Leu Ser Pro Leu Gln Ala 
    130                 135                 140                 


Glu Leu Leu Pro Pro Leu Leu Glu His Leu Leu Leu Pro Pro Gln Pro 
145                 150                 155                 160 


Pro His Pro Ser Leu Ser Tyr Glu Pro Ala Leu Leu Gln Pro Tyr Leu 
                165                 170                 175     


Phe His Gln Phe Gly Ser Arg Asp Gly Ser Arg Val Ser Glu Gly Ser 
            180                 185                 190         


Pro Gly Met Val Ser Val Gly Pro Leu Pro Lys Ala Glu Ala Pro Ala 
        195                 200                 205             


Leu Phe Ser Arg Thr Ala Ser Lys Gly Ile Phe Gly Asp His Pro Gly 
    210                 215                 220                 


His Ser Tyr Gly Asp Leu Pro Gly Pro Ser Pro Ala Gln Leu Phe Gln 
225                 230                 235                 240 


Asp Ser Gly Leu Leu Tyr Leu Ala Gln Glu Leu Pro Ala Pro Ser Arg 
                245                 250                 255     


Ala Arg Val Pro Arg Leu Pro Glu Gln Gly Ser Ser Ser Arg Ala Glu 
            260                 265                 270         


Asp Ser Pro Glu Gly Tyr Glu Lys Glu Gly Leu Gly Asp Arg Gly Glu 
        275                 280                 285             


Lys Pro Ala Ser Pro Ala Val Gln Pro Asp Ala Ala Leu Gln Arg Leu 
    290                 295                 300                 


Ala Ala Val Leu Ala Gly Tyr Gly Val Glu Leu Arg Gln Leu Thr Pro 
305                 310                 315                 320 


Glu Gln Leu Ser Thr Leu Leu Thr Leu Leu Gln Leu Leu Pro Lys Gly 
                325                 330                 335     


Ala Gly Arg Asn Pro Gly Gly Val Val Asn Val Gly Ala Asp Ile Lys 
            340                 345                 350         


Lys Thr Met Glu Gly Pro Val Glu Gly Arg Asp Thr Ala Glu Leu Pro 
        355                 360                 365             


Ala Arg Thr Ser Pro Met Pro Gly His Pro Thr Ala Ser Pro Thr Ser 
    370                 375                 380                 


Ser Glu Val Gln Gln Val Pro Ser Pro Val Ser Ser Glu Pro Pro Lys 
385                 390                 395                 400 


Ala Ala Arg Pro Pro Val Thr Pro Val Leu Leu Glu Lys Lys Ser Pro 
                405                 410                 415     


Leu Gly Gln Ser Gln Pro Thr Val Ala Gly Gln Pro Ser Ala Arg Pro 
            420                 425                 430         


Ala Ala Glu Glu Tyr Gly Tyr Ile Val Thr Asp Gln Asn Val Val Gly 
        435                 440                 445             


Pro Ala Leu Thr Phe Arg Ile Arg His Asn Glu Gln Asn Leu Ser Leu 
    450                 455                 460                 


Ala Asp Val Thr Gln Gln Ala Gly Leu Val Lys Ser Glu Leu Glu Ala 
465                 470                 475                 480 


Gln Thr Gly Leu Gln Ile Leu Gln Thr Gly Val Gly Gln Arg Glu Glu 
                485                 490                 495     


Ala Ala Ala Val Leu Pro Gln Thr Ala His Ser Thr Ser Pro Met Arg 
            500                 505                 510         


<210>  1131
<211>  793
<212>  PRT
<213>  Homo Sapiens

<400>  1131

Phe His Val Thr Val Gln Asp Asp Asn Asn Ile Val Val Ser Leu Glu 
1               5                   10                  15      


Ala Ser Asp Val Ile Ser Pro Ala Ser Val Tyr Val Val Lys Ile Thr 
            20                  25                  30          


Gly Glu Ser Lys Asn Tyr Phe Phe Glu Phe Glu Glu Phe Asn Ser Thr 
        35                  40                  45              


Leu Pro Pro Pro Val Ile Phe Lys Ala Ser Tyr His Gly Leu Tyr Tyr 
    50                  55                  60                  


Ile Ile Thr Leu Val Val Val Asn Gly Asn Val Val Thr Lys Pro Ser 
65                  70                  75                  80  


Arg Ser Ile Thr Val Leu Thr Lys Pro Leu Pro Val Thr Ser Val Ser 
                85                  90                  95      


Ile Tyr Asp Tyr Lys Pro Ser Pro Glu Thr Gly Val Leu Phe Glu Ile 
            100                 105                 110         


His Tyr Pro Glu Lys Tyr Asn Val Phe Thr Arg Val Asn Ile Ser Tyr 
        115                 120                 125             


Trp Glu Gly Lys Asp Phe Arg Thr Met Leu Tyr Lys Asp Phe Phe Lys 
    130                 135                 140                 


Gly Lys Thr Val Phe Asn His Trp Leu Pro Gly Met Cys Tyr Ser Asn 
145                 150                 155                 160 


Ile Thr Phe Gln Leu Val Ser Glu Ala Thr Phe Asn Lys Ser Thr Leu 
                165                 170                 175     


Val Glu Tyr Ser Gly Val Ser His Glu Pro Lys Gln His Arg Thr Ala 
            180                 185                 190         


Pro Tyr Pro Pro Gln Asn Ile Ser Val Arg Ile Val Asn Leu Asn Lys 
        195                 200                 205             


Asn Asn Trp Glu Glu Gln Ser Gly Asn Phe Pro Glu Glu Ser Phe Met 
    210                 215                 220                 


Arg Ser Gln Asp Thr Ile Gly Lys Glu Lys Leu Phe His Phe Thr Glu 
225                 230                 235                 240 


Glu Thr Pro Glu Ile Pro Ser Gly Asn Ile Ser Ser Gly Trp Pro Asp 
                245                 250                 255     


Phe Asn Ser Ser Asp Tyr Glu Thr Thr Ser Gln Pro Tyr Trp Trp Asp 
            260                 265                 270         


Ser Ala Ser Ala Ala Pro Glu Ser Glu Asp Glu Phe Val Ser Val Leu 
        275                 280                 285             


Pro Met Glu Tyr Glu Asn Asn Ser Thr Leu Ser Glu Thr Glu Lys Ser 
    290                 295                 300                 


Thr Ser Gly Ser Phe Ser Phe Phe Pro Val Gln Met Ile Leu Thr Trp 
305                 310                 315                 320 


Leu Pro Pro Lys Pro Pro Thr Ala Phe Asp Gly Phe His Ile His Ile 
                325                 330                 335     


Glu Arg Glu Glu Asn Phe Thr Glu Tyr Leu Met Val Asp Glu Glu Ala 
            340                 345                 350         


His Glu Phe Val Ala Glu Leu Lys Glu Pro Gly Lys Tyr Lys Leu Ser 
        355                 360                 365             


Val Thr Thr Phe Ser Ser Ser Gly Ser Cys Glu Thr Arg Lys Ser Gln 
    370                 375                 380                 


Ser Ala Lys Ser Leu Ser Phe Tyr Ile Ser Pro Ser Gly Glu Trp Ile 
385                 390                 395                 400 


Glu Glu Leu Thr Glu Lys Pro Gln His Val Ser Val His Val Leu Ser 
                405                 410                 415     


Ser Thr Thr Ala Leu Met Ser Trp Thr Ser Ser Gln Glu Asn Tyr Asn 
            420                 425                 430         


Ser Thr Ile Val Ser Val Val Ser Leu Thr Cys Gln Lys Gln Lys Glu 
        435                 440                 445             


Ser Gln Arg Leu Glu Lys Gln Tyr Cys Thr Gln Val Asn Ser Ser Lys 
    450                 455                 460                 


Pro Ile Ile Glu Asn Leu Val Pro Gly Ala Gln Tyr Gln Val Val Ile 
465                 470                 475                 480 


Tyr Leu Arg Lys Gly Pro Leu Ile Gly Pro Pro Ser Asp Pro Val Thr 
                485                 490                 495     


Phe Ala Ile Val Pro Thr Gly Ile Lys Asp Leu Met Leu Tyr Pro Leu 
            500                 505                 510         


Gly Pro Thr Ala Val Val Leu Ser Trp Thr Arg Pro Tyr Leu Gly Val 
        515                 520                 525             


Phe Arg Lys Tyr Val Val Glu Met Phe Tyr Phe Asn Pro Ala Thr Met 
    530                 535                 540                 


Thr Ser Glu Trp Thr Thr Tyr Tyr Glu Ile Ala Ala Thr Val Ser Leu 
545                 550                 555                 560 


Thr Ala Ser Val Arg Ile Ala Asn Leu Leu Pro Ala Trp Tyr Tyr Asn 
                565                 570                 575     


Phe Arg Val Thr Met Val Thr Trp Gly Asp Pro Glu Leu Ser Cys Cys 
            580                 585                 590         


Asp Ser Ser Thr Ile Ser Phe Ile Thr Ala Pro Val Ala Pro Glu Ile 
        595                 600                 605             


Thr Ser Val Glu Tyr Phe Asn Ser Leu Leu Tyr Ile Ser Trp Thr Tyr 
    610                 615                 620                 


Gly Asp Asp Thr Thr Asp Leu Ser His Ser Arg Met Leu His Trp Met 
625                 630                 635                 640 


Val Val Ala Glu Gly Lys Lys Lys Ile Lys Lys Ser Val Thr Arg Asn 
                645                 650                 655     


Val Met Thr Ala Ile Leu Ser Leu Pro Pro Gly Asp Ile Tyr Asn Leu 
            660                 665                 670         


Ser Val Thr Ala Cys Thr Glu Arg Gly Ser Asn Thr Ser Met Leu Arg 
        675                 680                 685             


Leu Val Lys Leu Glu Pro Ala Pro Pro Lys Ser Leu Phe Ala Val Asn 
    690                 695                 700                 


Lys Thr Gln Thr Ser Val Thr Leu Leu Trp Val Glu Glu Gly Val Ala 
705                 710                 715                 720 


Asp Phe Phe Glu Val Phe Cys Gln Gln Val Gly Ser Ser Gln Lys Thr 
                725                 730                 735     


Lys Leu Gln Glu Pro Val Ala Val Ser Ser His Val Val Thr Ile Ser 
            740                 745                 750         


Ser Leu Leu Pro Ala Thr Ala Tyr Asn Cys Ser Val Thr Ser Phe Ser 
        755                 760                 765             


His Asp Ser Pro Ser Val Pro Thr Phe Ile Ala Val Ser Thr Met Val 
    770                 775                 780                 


Thr Glu Met Asn Pro Asn Val Val Val 
785                 790             


<210>  1132
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  1132

Phe Ser Gly Asn Asn Asp His Phe Leu Ala Ile Asn Gln Lys Lys Ser 
1               5                   10                  15      


Gly Lys Pro Val Phe Ile Tyr Lys His Ser Gln Asp Ile Glu Lys Ser 
            20                  25                  30          


Leu Asp Ile Ala Pro Gln Lys Ile Tyr Arg His Ser Tyr His Ser Ser 
        35                  40                  45              


Ser Glu Ala Gln Val Ser Lys Arg His Gln Ile Val Asn Ser Ala Phe 
    50                  55                  60                  


Pro Arg Pro Ala Tyr Asp Pro Ser Leu Asn Leu Leu Ala Met Asp Gly 
65                  70                  75                  80  


Gln Asp Leu Glu Val Glu Asn Leu Pro Ile Pro Ala Ala Asn Val Ile 
                85                  90                  95      


Val Val Thr Leu Gln Met Asp Val Asn Lys Leu Asn Ile Thr Leu Leu 
            100                 105                 110         


Arg Ile Phe Arg Gln Gly Val Ala Ala Ala Leu Gly Leu Leu Pro Gln 
        115                 120                 125             


Gln Val His Ile Asn Arg Leu Ile Gly Lys Lys Asn Ser Ile Glu Leu 
    130                 135                 140                 


Phe Val Ser Pro Ile Asn Arg Lys Thr Gly Ile Ser Asp Ala Leu Pro 
145                 150                 155                 160 


Ser Glu Glu Val Leu Arg Ser Leu Asn Ile Asn Val Leu His Gln Ser 
                165                 170                 175     


Leu Ser Gln Phe Gly Ile Thr Glu Val Ser Pro Glu Lys Asn Val Leu 
            180                 185                 190         


Gln Gly Gln His Glu Ala Asp Lys Ile Trp Ser Lys Glu Gly 
        195                 200                 205     


<210>  1133
<211>  822
<212>  PRT
<213>  Homo Sapiens

<400>  1133

Glu Glu Pro Pro Arg Phe Ile Lys Glu Pro Lys Asp Gln Ile Gly Val 
1               5                   10                  15      


Ser Gly Gly Val Ala Ser Phe Val Cys Gln Ala Thr Gly Asp Pro Lys 
            20                  25                  30          


Pro Arg Val Thr Trp Asn Lys Lys Gly Lys Lys Val Asn Ser Gln Arg 
        35                  40                  45              


Phe Glu Thr Ile Glu Phe Asp Glu Ser Ala Gly Ala Val Leu Arg Ile 
    50                  55                  60                  


Gln Pro Leu Arg Thr Pro Arg Asp Glu Asn Val Tyr Glu Cys Val Ala 
65                  70                  75                  80  


Gln Asn Ser Val Gly Glu Ile Thr Val His Ala Lys Leu Thr Val Leu 
                85                  90                  95      


Arg Glu Asp Gln Leu Pro Ser Gly Phe Pro Asn Ile Asp Met Gly Pro 
            100                 105                 110         


Gln Leu Lys Val Val Glu Arg Thr Arg Thr Ala Thr Met Leu Cys Ala 
        115                 120                 125             


Ala Ser Gly Asn Pro Asp Pro Glu Ile Thr Trp Phe Lys Asp Phe Leu 
    130                 135                 140                 


Pro Val Asp Pro Ser Ala Ser Asn Gly Arg Ile Lys Gln Leu Arg Ser 
145                 150                 155                 160 


Gly Ala Leu Gln Ile Glu Ser Ser Glu Glu Thr Asp Gln Gly Lys Tyr 
                165                 170                 175     


Glu Cys Val Ala Thr Asn Ser Ala Gly Val Arg Tyr Ser Ser Pro Ala 
            180                 185                 190         


Asn Leu Tyr Val Arg Val Arg Arg Val Ala Pro Arg Phe Ser Ile Leu 
        195                 200                 205             


Pro Met Ser His Glu Ile Met Pro Gly Gly Asn Val Asn Ile Thr Cys 
    210                 215                 220                 


Val Ala Val Gly Ser Pro Met Pro Tyr Val Lys Trp Met Gln Gly Ala 
225                 230                 235                 240 


Glu Asp Leu Thr Pro Glu Asp Asp Met Pro Val Gly Arg Asn Val Leu 
                245                 250                 255     


Glu Leu Thr Asp Val Lys Asp Ser Ala Asn Tyr Thr Cys Val Ala Met 
            260                 265                 270         


Ser Ser Leu Gly Val Ile Glu Ala Val Ala Gln Ile Thr Val Lys Ser 
        275                 280                 285             


Leu Pro Lys Ala Pro Gly Thr Pro Met Val Thr Glu Asn Thr Ala Thr 
    290                 295                 300                 


Ser Ile Thr Ile Thr Trp Asp Ser Gly Asn Pro Asp Pro Val Ser Tyr 
305                 310                 315                 320 


Tyr Val Ile Glu Tyr Lys Ser Lys Ser Gln Asp Gly Pro Tyr Gln Ile 
                325                 330                 335     


Lys Glu Asp Ile Thr Thr Thr Arg Tyr Ser Ile Gly Gly Leu Ser Pro 
            340                 345                 350         


Asn Ser Glu Tyr Glu Ile Trp Val Ser Ala Val Asn Ser Ile Gly Gln 
        355                 360                 365             


Gly Pro Pro Ser Glu Ser Val Val Thr Arg Thr Gly Glu Gln Ala Pro 
    370                 375                 380                 


Ala Ser Ala Pro Arg Asn Val Gln Ala Arg Met Leu Ser Ala Thr Thr 
385                 390                 395                 400 


Met Ile Val Gln Trp Glu Glu Pro Val Glu Pro Asn Gly Leu Ile Arg 
                405                 410                 415     


Gly Tyr Arg Val Tyr Tyr Thr Met Glu Pro Glu His Pro Val Gly Asn 
            420                 425                 430         


Trp Gln Lys His Asn Val Asp Asp Ser Leu Leu Thr Thr Val Gly Ser 
        435                 440                 445             


Leu Leu Glu Asp Glu Thr Tyr Thr Val Arg Val Leu Ala Phe Thr Ser 
    450                 455                 460                 


Val Gly Asp Gly Pro Leu Ser Asp Pro Ile Gln Val Lys Thr Gln Gln 
465                 470                 475                 480 


Gly Val Pro Gly Gln Pro Met Asn Leu Arg Ala Glu Ala Arg Ser Glu 
                485                 490                 495     


Thr Ser Ile Thr Leu Ser Trp Ser Pro Pro Arg Gln Glu Ser Ile Ile 
            500                 505                 510         


Lys Tyr Glu Leu Leu Phe Arg Glu Gly Asp His Gly Arg Glu Val Gly 
        515                 520                 525             


Arg Thr Phe Asp Pro Thr Thr Ser Tyr Val Val Glu Asp Leu Lys Pro 
    530                 535                 540                 


Asn Thr Glu Tyr Ala Phe Arg Leu Ala Ala Arg Ser Pro Gln Gly Leu 
545                 550                 555                 560 


Gly Ala Phe Thr Pro Val Val Arg Gln Arg Thr Leu Gln Ser Ile Ser 
                565                 570                 575     


Pro Lys Asn Phe Lys Val Lys Met Ile Met Lys Thr Ser Val Leu Leu 
            580                 585                 590         


Ser Trp Glu Phe Pro Asp Asn Tyr Asn Ser Pro Thr Pro Tyr Lys Ile 
        595                 600                 605             


Gln Tyr Asn Gly Leu Thr Leu Asp Val Asp Gly Arg Thr Thr Lys Lys 
    610                 615                 620                 


Leu Ile Thr His Leu Lys Pro His Thr Phe Tyr Asn Phe Val Leu Thr 
625                 630                 635                 640 


Asn Arg Gly Ser Ser Leu Gly Gly Leu Gln Gln Thr Val Thr Ala Trp 
                645                 650                 655     


Thr Ala Phe Asn Leu Leu Asn Gly Lys Pro Ser Val Ala Pro Lys Pro 
            660                 665                 670         


Asp Ala Asp Gly Phe Ile Met Val Tyr Leu Pro Asp Gly Gln Ser Pro 
        675                 680                 685             


Val Pro Val Gln Ser Tyr Phe Ile Val Met Val Pro Leu Arg Lys Ser 
    690                 695                 700                 


Arg Gly Gly Gln Phe Leu Thr Pro Leu Gly Ser Pro Glu Asp Met Asp 
705                 710                 715                 720 


Leu Glu Glu Leu Ile Gln Asp Ile Ser Arg Leu Gln Arg Arg Ser Leu 
                725                 730                 735     


Arg His Ser Arg Gln Leu Glu Val Pro Arg Pro Tyr Ile Ala Ala Arg 
            740                 745                 750         


Phe Ser Val Leu Pro Pro Thr Phe His Pro Gly Asp Gln Lys Gln Tyr 
        755                 760                 765             


Gly Gly Phe Asp Asn Arg Gly Leu Glu Pro Gly His Arg Tyr Val Leu 
    770                 775                 780                 


Phe Val Leu Ala Val Leu Gln Lys Ser Glu Pro Thr Phe Ala Ala Ser 
785                 790                 795                 800 


Pro Phe Ser Asp Pro Phe Gln Leu Asp Asn Pro Asp Pro Gln Pro Ile 
                805                 810                 815     


Val Asp Gly Glu Glu Gly 
            820         


<210>  1134
<211>  364
<212>  PRT
<213>  Homo Sapiens

<400>  1134

Glu Asn Ser Asp Asp Tyr Asp Leu Met Tyr Val Asn Leu Asp Asn Glu 
1               5                   10                  15      


Ile Asp Asn Gly Leu His Pro Thr Glu Asp Pro Thr Pro Cys Asp Cys 
            20                  25                  30          


Gly Gln Glu His Ser Glu Trp Asp Lys Leu Phe Ile Met Leu Glu Asn 
        35                  40                  45              


Ser Gln Met Arg Glu Arg Met Leu Leu Gln Ala Thr Asp Asp Val Leu 
    50                  55                  60                  


Arg Gly Glu Leu Gln Arg Leu Arg Glu Glu Leu Gly Arg Leu Ala Glu 
65                  70                  75                  80  


Ser Leu Ala Arg Pro Cys Ala Pro Gly Ala Pro Ala Glu Ala Arg Leu 
                85                  90                  95      


Thr Ser Ala Leu Asp Glu Leu Leu Gln Ala Thr Arg Asp Ala Gly Arg 
            100                 105                 110         


Arg Leu Ala Arg Met Glu Gly Ala Glu Ala Gln Arg Pro Glu Glu Ala 
        115                 120                 125             


Gly Arg Ala Leu Ala Ala Val Leu Glu Glu Leu Arg Gln Thr Arg Ala 
    130                 135                 140                 


Asp Leu His Ala Val Gln Gly Trp Ala Ala Arg Ser Trp Leu Pro Ala 
145                 150                 155                 160 


Gly Cys Glu Thr Ala Ile Leu Phe Pro Met Arg Ser Lys Lys Ile Phe 
                165                 170                 175     


Gly Ser Val His Pro Val Arg Pro Met Arg Leu Glu Ser Phe Ser Ala 
            180                 185                 190         


Cys Ile Trp Val Lys Ala Thr Asp Val Leu Asn Lys Thr Ile Leu Phe 
        195                 200                 205             


Ser Tyr Gly Thr Lys Arg Asn Pro Tyr Glu Ile Gln Leu Tyr Leu Ser 
    210                 215                 220                 


Tyr Gln Ser Ile Val Phe Val Val Gly Gly Glu Glu Asn Lys Leu Val 
225                 230                 235                 240 


Ala Glu Ala Met Val Ser Leu Gly Arg Trp Thr His Leu Cys Gly Thr 
                245                 250                 255     


Trp Asn Ser Glu Glu Gly Leu Thr Ser Leu Trp Val Asn Gly Glu Leu 
            260                 265                 270         


Ala Ala Thr Thr Val Glu Met Ala Thr Gly His Ile Val Pro Glu Gly 
        275                 280                 285             


Gly Ile Leu Gln Ile Gly Gln Glu Lys Asn Gly Cys Cys Val Gly Gly 
    290                 295                 300                 


Gly Phe Asp Glu Thr Leu Ala Phe Ser Gly Arg Leu Thr Gly Phe Asn 
305                 310                 315                 320 


Ile Trp Asp Ser Val Leu Ser Asn Glu Glu Ile Arg Glu Thr Gly Gly 
                325                 330                 335     


Ala Glu Ser Cys His Ile Arg Gly Asn Ile Val Gly Trp Gly Val Thr 
            340                 345                 350         


Glu Ile Gln Pro His Gly Gly Ala Gln Tyr Val Ser 
        355                 360                 


<210>  1135
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  1135

Trp Pro Pro Pro Gly Thr Gly Asp Val Val Val Gln Ala Pro Thr Gln 
1               5                   10                  15      


Val Pro Gly Phe Leu Gly Asp Ser Val Thr Leu Pro Cys Tyr Leu Gln 
            20                  25                  30          


Val Pro Asn Met Glu Val Thr His Val Ser Gln Leu Thr Trp Ala Arg 
        35                  40                  45              


His Gly Glu Ser Gly Ser Met Ala Val Phe His Gln Thr Gln Gly Pro 
    50                  55                  60                  


Ser Tyr Ser Glu Ser Lys Arg Leu Glu Phe Val Ala Ala Arg Leu Gly 
65                  70                  75                  80  


Ala Glu Leu Arg Asn Ala Ser Leu Arg Met Phe Gly Leu Arg Val Glu 
                85                  90                  95      


Asp Glu Gly Asn Tyr Thr Cys Leu Phe Val Thr Phe Pro Gln Gly Ser 
            100                 105                 110         


Arg Ser Val Asp Ile Trp Leu Arg Val Leu Ala Lys Pro Gln Asn Thr 
        115                 120                 125             


Ala Glu Val Gln Lys Val Gln Leu Thr Gly Glu Pro Val Pro Met Ala 
    130                 135                 140                 


Arg Cys Val Ser Thr Gly Gly Arg Pro Pro Ala Gln Ile Thr Trp His 
145                 150                 155                 160 


Ser Asp Leu Gly Gly Met Pro Asn Thr Ser Gln Val Pro Gly Phe Leu 
                165                 170                 175     


Ser Gly Thr Val Thr Val Thr Ser Leu Trp Ile Leu Val Pro Ser Ser 
            180                 185                 190         


Gln Val Asp Gly Lys Asn Val Thr Cys Lys Val Glu His Glu Ser Phe 
        195                 200                 205             


Glu Lys Pro Gln Leu Leu Thr Val Asn Leu Thr Val Tyr Tyr Pro Pro 
    210                 215                 220                 


Glu Val Ser Ile Ser Gly Tyr Asp Asn Asn Trp Tyr Leu Gly Gln Asn 
225                 230                 235                 240 


Glu Ala Thr Leu Thr Cys Asp Ala Arg Ser Asn Pro Glu Pro Thr Gly 
                245                 250                 255     


Tyr Asn Trp Ser Thr Thr Met Gly Pro Leu Pro Pro Phe Ala Val Ala 
            260                 265                 270         


Gln Gly Ala Gln Leu Leu Ile Arg Pro Val Asp Lys Pro Ile Asn Thr 
        275                 280                 285             


Thr Leu Ile Cys Asn Val Thr Asn Ala Leu Gly Ala Arg Gln Ala Glu 
    290                 295                 300                 


Leu Thr Val Gln Val Lys Glu Gly Pro Pro Ser Glu His Ser Gly Met 
305                 310                 315                 320 


Ser Arg Asn 
            


<210>  1136
<211>  325
<212>  PRT
<213>  Homo Sapiens

<400>  1136

Gln Val Val Gln Val Asn Asp Ser Met Tyr Gly Phe Ile Gly Thr Asp 
1               5                   10                  15      


Val Val Leu His Cys Ser Phe Ala Asn Pro Leu Pro Ser Val Lys Ile 
            20                  25                  30          


Thr Gln Val Thr Trp Gln Lys Ser Thr Asn Gly Ser Lys Gln Asn Val 
        35                  40                  45              


Ala Ile Tyr Asn Pro Ser Met Gly Val Ser Val Leu Ala Pro Tyr Arg 
    50                  55                  60                  


Glu Arg Val Glu Phe Leu Arg Pro Ser Phe Thr Asp Gly Thr Ile Arg 
65                  70                  75                  80  


Leu Ser Arg Leu Glu Leu Glu Asp Glu Gly Val Tyr Ile Cys Glu Phe 
                85                  90                  95      


Ala Thr Phe Pro Thr Gly Asn Arg Glu Ser Gln Leu Asn Leu Thr Val 
            100                 105                 110         


Met Ala Lys Pro Thr Asn Trp Ile Glu Gly Thr Gln Ala Val Leu Arg 
        115                 120                 125             


Ala Lys Lys Gly Gln Asp Asp Lys Val Leu Val Ala Thr Cys Thr Ser 
    130                 135                 140                 


Ala Asn Gly Lys Pro Pro Ser Val Val Ser Trp Glu Thr Arg Leu Lys 
145                 150                 155                 160 


Gly Glu Ala Glu Tyr Gln Glu Ile Arg Asn Pro Asn Gly Thr Val Thr 
                165                 170                 175     


Val Ile Ser Arg Tyr Arg Leu Val Pro Ser Arg Glu Ala His Gln Gln 
            180                 185                 190         


Ser Leu Ala Cys Ile Val Asn Tyr His Met Asp Arg Phe Lys Glu Ser 
        195                 200                 205             


Leu Thr Leu Asn Val Gln Tyr Glu Pro Glu Val Thr Ile Glu Gly Phe 
    210                 215                 220                 


Asp Gly Asn Trp Tyr Leu Gln Arg Met Asp Val Lys Leu Thr Cys Lys 
225                 230                 235                 240 


Ala Asp Ala Asn Pro Pro Ala Thr Glu Tyr His Trp Thr Thr Leu Asn 
                245                 250                 255     


Gly Ser Leu Pro Lys Gly Val Glu Ala Gln Asn Arg Thr Leu Phe Phe 
            260                 265                 270         


Lys Gly Pro Ile Asn Tyr Ser Leu Ala Gly Thr Tyr Ile Cys Glu Ala 
        275                 280                 285             


Thr Asn Pro Ile Gly Thr Arg Ser Gly Gln Val Glu Val Asn Ile Thr 
    290                 295                 300                 


Glu Phe Pro Tyr Thr Pro Ser Pro Pro Glu His Gly Arg Arg Ala Gly 
305                 310                 315                 320 


Pro Val Pro Thr Ala 
                325 


<210>  1137
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  1137

Gln Asp Val Arg Val Gln Val Leu Pro Glu Val Arg Gly Gln Leu Gly 
1               5                   10                  15      


Gly Thr Val Glu Leu Pro Cys His Leu Leu Pro Pro Val Pro Gly Leu 
            20                  25                  30          


Tyr Ile Ser Leu Val Thr Trp Gln Arg Pro Asp Ala Pro Ala Asn His 
        35                  40                  45              


Gln Asn Val Ala Ala Phe His Pro Lys Met Gly Pro Ser Phe Pro Ser 
    50                  55                  60                  


Pro Lys Pro Gly Ser Glu Arg Leu Ser Phe Val Ser Ala Lys Gln Ser 
65                  70                  75                  80  


Thr Gly Gln Asp Thr Glu Ala Glu Leu Gln Asp Ala Thr Leu Ala Leu 
                85                  90                  95      


His Gly Leu Thr Val Glu Asp Glu Gly Asn Tyr Thr Cys Glu Phe Ala 
            100                 105                 110         


Thr Phe Pro Lys Gly Ser Val Arg Gly Met Thr Trp Leu Arg Val Ile 
        115                 120                 125             


Ala Lys Pro Lys Asn Gln Ala Glu Ala Gln Lys Val Thr Phe Ser Gln 
    130                 135                 140                 


Asp Pro Thr Thr Val Ala Leu Cys Ile Ser Lys Glu Gly Arg Pro Pro 
145                 150                 155                 160 


Ala Arg Ile Ser Trp Leu Ser Ser Leu Asp Trp Glu Ala Lys Glu Thr 
                165                 170                 175     


Gln Val Ser Gly Thr Leu Ala Gly Thr Val Thr Val Thr Ser Arg Phe 
            180                 185                 190         


Thr Leu Val Pro Ser Gly Arg Ala Asp Gly Val Thr Val Thr Cys Lys 
        195                 200                 205             


Val Glu His Glu Ser Phe Glu Glu Pro Ala Leu Ile Pro Val Thr Leu 
    210                 215                 220                 


Ser Val Arg Tyr Pro Pro Glu Val Ser Ile Ser Gly Tyr Asp Asp Asn 
225                 230                 235                 240 


Trp Tyr Leu Gly Arg Thr Asp Ala Thr Leu Ser Cys Asp Val Arg Ser 
                245                 250                 255     


Asn Pro Glu Pro Thr Gly Tyr Asp Trp Ser Thr Thr Ser Gly Thr Phe 
            260                 265                 270         


Pro Thr Ser Ala Val Ala Gln Gly Ser Gln Leu Val Ile His Ala Val 
        275                 280                 285             


Asp Ser Leu Phe Asn Thr Thr Phe Val Cys Thr Val Thr Asn Ala Val 
    290                 295                 300                 


Gly Met Gly Arg Ala Glu Gln Val Ile Phe Val Arg Glu Thr Pro Arg 
305                 310                 315                 320 


Ala Ser Pro Arg Asp Val Gly Pro Leu 
                325                 


<210>  1138
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  1138

Gly Pro Ile Ile Val Glu Pro His Val Thr Ala Val Trp Gly Lys Asn 
1               5                   10                  15      


Val Ser Leu Lys Cys Leu Ile Glu Val Asn Glu Thr Ile Thr Gln Ile 
            20                  25                  30          


Ser Trp Glu Lys Ile His Gly Lys Ser Ser Gln Thr Val Ala Val His 
        35                  40                  45              


His Pro Gln Tyr Gly Phe Ser Val Gln Gly Glu Tyr Gln Gly Arg Val 
    50                  55                  60                  


Leu Phe Lys Asn Tyr Ser Leu Asn Asp Ala Thr Ile Thr Leu His Asn 
65                  70                  75                  80  


Ile Gly Phe Ser Asp Ser Gly Lys Tyr Ile Cys Lys Ala Val Thr Phe 
                85                  90                  95      


Pro Leu Gly Asn Ala Gln Ser Ser Thr Thr Val Thr Val Leu Val Glu 
            100                 105                 110         


Pro Thr Val Ser Leu Ile Lys Gly Pro Asp Ser Leu Ile Asp Gly Gly 
        115                 120                 125             


Asn Glu Thr Val Ala Ala Ile Cys Ile Ala Ala Thr Gly Lys Pro Val 
    130                 135                 140                 


Ala His Ile Asp Trp Glu Gly Asp Leu Gly Glu Met Glu Ser Thr Thr 
145                 150                 155                 160 


Thr Ser Phe Pro Asn Glu Thr Ala Thr Ile Ile Ser Gln Tyr Lys Leu 
                165                 170                 175     


Phe Pro Thr Arg Phe Ala Arg Gly Arg Arg Ile Thr Cys Val Val Lys 
            180                 185                 190         


His Gln Ala Leu Glu Lys Asp Ile Arg Tyr Ser Phe Ile Leu Asp Ile 
        195                 200                 205             


Gln Tyr Ala Pro Glu Val Ser Val Thr Gly Tyr Asp Gly Asn Trp Phe 
    210                 215                 220                 


Val Gly Arg Lys Gly Val Asn Leu Lys Cys Asn Ala Asp Ala Asn Pro 
225                 230                 235                 240 


Pro Pro Phe Lys Ser Val Trp Ser Arg Leu Asp Gly Gln Trp Pro Asp 
                245                 250                 255     


Gly Leu Leu Ala Ser Asp Asn Thr Leu His Phe Val His Pro Leu Thr 
            260                 265                 270         


Phe Asn Tyr Ser Gly Val Tyr Ile Cys Lys Val Thr Asn Ser Leu Gly 
        275                 280                 285             


Gln Arg Ser Asp Gln Lys Val Ile Tyr Ile Ser Ala Tyr Asn Ser Val 
    290                 295                 300                 


Ala Ser Leu Asn Cys 
305                 


<210>  1139
<211>  318
<212>  PRT
<213>  Homo Sapiens

<400>  1139

Gly Glu Leu Glu Thr Ser Asp Val Val Thr Val Val Leu Gly Gln Asp 
1               5                   10                  15      


Ala Lys Leu Pro Cys Phe Tyr Arg Gly Asp Ser Gly Glu Gln Val Gly 
            20                  25                  30          


Gln Val Ala Trp Ala Arg Val Asp Ala Gly Glu Gly Ala Gln Glu Leu 
        35                  40                  45              


Ala Leu Leu His Ser Lys Tyr Gly Leu His Val Ser Pro Ala Tyr Glu 
    50                  55                  60                  


Gly Arg Val Glu Gln Pro Pro Pro Pro Arg Asn Pro Leu Asp Gly Ser 
65                  70                  75                  80  


Val Leu Leu Arg Asn Ala Val Gln Ala Asp Glu Gly Glu Tyr Glu Cys 
                85                  90                  95      


Arg Val Ser Thr Phe Pro Ala Gly Ser Phe Gln Ala Arg Leu Arg Leu 
            100                 105                 110         


Arg Val Leu Val Pro Pro Leu Pro Ser Leu Asn Pro Gly Pro Ala Leu 
        115                 120                 125             


Glu Glu Gly Gln Gly Leu Thr Leu Ala Ala Ser Cys Thr Ala Glu Gly 
    130                 135                 140                 


Ser Pro Ala Pro Ser Val Thr Trp Asp Thr Glu Val Lys Gly Thr Thr 
145                 150                 155                 160 


Ser Ser Arg Ser Phe Lys His Ser Arg Ser Ala Ala Val Thr Ser Glu 
                165                 170                 175     


Phe His Leu Val Pro Ser Arg Ser Met Asn Gly Gln Pro Leu Thr Cys 
            180                 185                 190         


Val Val Ser His Pro Gly Leu Leu Gln Asp Gln Arg Ile Thr His Ile 
        195                 200                 205             


Leu His Val Ser Phe Leu Ala Glu Ala Ser Val Arg Gly Leu Glu Asp 
    210                 215                 220                 


Gln Asn Leu Trp His Ile Gly Arg Glu Gly Ala Met Leu Lys Cys Leu 
225                 230                 235                 240 


Ser Glu Gly Gln Pro Pro Pro Ser Tyr Asn Trp Thr Arg Leu Asp Gly 
                245                 250                 255     


Pro Leu Pro Ser Gly Val Arg Val Asp Gly Asp Thr Leu Gly Phe Pro 
            260                 265                 270         


Pro Leu Thr Thr Glu His Ser Gly Ile Tyr Val Cys His Val Ser Asn 
        275                 280                 285             


Glu Phe Ser Ser Arg Asp Ser Gln Val Thr Val Asp Val Leu Asp Pro 
    290                 295                 300                 


Gln Glu Asp Ser Gly Lys Gln Val Asp Leu Val Ser Ala Ser 
305                 310                 315             


<210>  1140
<211>  1268
<212>  PRT
<213>  Homo Sapiens

<400>  1140

Met Ser Glu Ser Tyr Arg Arg Thr Thr Phe Pro Val Arg Phe Arg Val 
1               5                   10                  15      


Val Ser Val Asp Glu Asn Phe Arg Pro Arg Asn Glu Leu Ile Pro Leu 
            20                  25                  30          


Ile Tyr Leu Glu Asn Pro Arg Arg Asn Arg Ile Ala Gln Trp Gln Ser 
        35                  40                  45              


Leu Lys Leu Glu Ala Gly Ile Asn Gln Leu Ser Phe Pro Leu Ser Ser 
    50                  55                  60                  


Glu Pro Ile Gln Gly Ser Tyr Arg Val Val Val Gln Thr Glu Ser Gly 
65                  70                  75                  80  


Gly Arg Ile Gln His Pro Phe Thr Val Glu Glu Phe Val Leu Pro Lys 
                85                  90                  95      


Phe Glu Val Lys Val Gln Val Pro Lys Ile Ile Ser Ile Met Asp Glu 
            100                 105                 110         


Lys Val Asn Ile Thr Val Cys Gly Glu Tyr Thr Tyr Gly Lys Pro Val 
        115                 120                 125             


Pro Gly Leu Ala Thr Val Ser Leu Cys Arg Lys Leu Ser Arg Val Leu 
    130                 135                 140                 


Asn Cys Asp Lys Gln Glu Val Cys Glu Glu Phe Ser Gln Gln Leu Asn 
145                 150                 155                 160 


Ser Asn Gly Cys Ile Thr Gln Gln Val His Thr Lys Met Leu Gln Ile 
                165                 170                 175     


Thr Asn Thr Gly Phe Glu Met Lys Leu Arg Val Glu Ala Arg Ile Arg 
            180                 185                 190         


Glu Glu Gly Thr Asp Leu Glu Val Thr Ala Asn Arg Ile Ser Glu Ile 
        195                 200                 205             


Thr Asn Ile Val Ser Lys Leu Lys Phe Val Lys Val Asp Ser His Phe 
    210                 215                 220                 


Arg Gln Gly Ile Pro Phe Phe Ala Gln Val Leu Leu Val Asp Gly Lys 
225                 230                 235                 240 


Gly Val Pro Ile Pro Asn Lys Leu Phe Phe Ile Ser Val Asn Asp Ala 
                245                 250                 255     


Asn Tyr Tyr Ser Asn Ala Thr Thr Asn Glu Gln Gly Leu Ala Gln Phe 
            260                 265                 270         


Ser Ile Asn Thr Thr Ser Ile Ser Val Asn Lys Leu Phe Val Arg Val 
        275                 280                 285             


Phe Thr Val His Pro Asn Leu Cys Phe His Tyr Ser Trp Val Ala Glu 
    290                 295                 300                 


Asp His Gln Gly Ala Gln His Thr Ala Asn Arg Val Phe Ser Leu Ser 
305                 310                 315                 320 


Gly Ser Tyr Ile His Leu Glu Pro Val Ala Gly Thr Leu Pro Cys Gly 
                325                 330                 335     


His Thr Glu Thr Ile Thr Ala His Tyr Thr Leu Asn Arg Gln Ala Met 
            340                 345                 350         


Gly Glu Leu Ser Glu Leu Ser Phe His Tyr Leu Ile Met Ala Lys Gly 
        355                 360                 365             


Val Ile Val Arg Ser Gly Thr His Thr Leu Pro Val Glu Ser Gly Asp 
    370                 375                 380                 


Met Lys Gly Ser Phe Ala Leu Ser Phe Pro Val Glu Ser Asp Val Ala 
385                 390                 395                 400 


Pro Ile Ala Arg Met Phe Ile Phe Ala Ile Leu Pro Asp Gly Glu Val 
                405                 410                 415     


Val Gly Asp Ser Glu Lys Phe Glu Ile Glu Asn Cys Leu Ala Asn Lys 
            420                 425                 430         


Val Asp Leu Ser Phe Ser Pro Ala Gln Ser Pro Pro Ala Ser His Ala 
        435                 440                 445             


His Leu Gln Val Ala Ala Ala Pro Gln Ser Leu Cys Ala Leu Arg Ala 
    450                 455                 460                 


Val Asp Gln Ser Val Leu Leu Met Lys Pro Glu Ala Glu Leu Ser Val 
465                 470                 475                 480 


Ser Ser Val Tyr Asn Leu Leu Thr Val Lys Asp Leu Thr Asn Phe Pro 
                485                 490                 495     


Asp Asn Val Asp Gln Gln Glu Glu Glu Gln Gly His Cys Pro Arg Pro 
            500                 505                 510         


Phe Phe Ile His Asn Gly Ala Ile Tyr Val Pro Leu Ser Ser Asn Glu 
        515                 520                 525             


Ala Asp Ile Tyr Ser Phe Leu Lys Gly Met Gly Leu Lys Val Phe Thr 
    530                 535                 540                 


Asn Ser Lys Ile Arg Lys Pro Lys Ser Cys Ser Val Ile Pro Ser Val 
545                 550                 555                 560 


Ser Ala Gly Ala Val Gly Gln Gly Tyr Tyr Gly Ala Gly Leu Gly Val 
                565                 570                 575     


Val Glu Arg Pro Tyr Val Pro Gln Leu Gly Thr Tyr Asn Val Ile Pro 
            580                 585                 590         


Leu Asn Asn Glu Gln Ser Ser Gly Pro Val Pro Glu Thr Val Arg Ser 
        595                 600                 605             


Tyr Phe Pro Glu Thr Trp Ile Trp Glu Leu Val Ala Val Asn Ser Ser 
    610                 615                 620                 


Gly Val Ala Glu Val Gly Val Thr Val Pro Asp Thr Ile Thr Glu Trp 
625                 630                 635                 640 


Lys Ala Gly Ala Phe Cys Leu Ser Glu Asp Ala Gly Leu Gly Ile Ser 
                645                 650                 655     


Ser Thr Ala Ser Leu Arg Ala Phe Gln Pro Phe Phe Val Glu Leu Thr 
            660                 665                 670         


Met Pro Tyr Ser Val Ile Arg Gly Glu Val Phe Thr Leu Lys Ala Thr 
        675                 680                 685             


Val Leu Asn Tyr Leu Pro Lys Cys Ile Arg Ala Glu Gly Ile Glu Gln 
    690                 695                 700                 


Glu Lys Thr Phe Ser Ser Met Thr Cys Ala Ser Gly Ala Asn Val Ser 
705                 710                 715                 720 


Glu Gln Leu Ser Leu Lys Leu Pro Ser Asn Val Val Lys Glu Ser Ala 
                725                 730                 735     


Arg Ala Ser Phe Ser Val Leu Gly Asp Ile Leu Gly Ser Ala Met Gln 
            740                 745                 750         


Asn Ile Gln Asn Leu Leu Gln Met Pro Tyr Gly Cys Gly Glu Gln Asn 
        755                 760                 765             


Met Val Leu Phe Ala Pro Asn Ile Tyr Val Leu Asn Tyr Leu Asn Glu 
    770                 775                 780                 


Thr Gln Gln Leu Thr Gln Glu Ile Lys Ala Lys Ala Val Gly Tyr Leu 
785                 790                 795                 800 


Ile Thr Gly Tyr Gln Arg Gln Leu Asn Tyr Lys His Gln Asp Gly Ser 
                805                 810                 815     


Tyr Ser Thr Phe Gly Glu Arg Tyr Gly Arg Asn Gln Gly Asn Thr Trp 
            820                 825                 830         


Leu Thr Ala Phe Val Leu Lys Thr Phe Ala Gln Ala Arg Ser Tyr Ile 
        835                 840                 845             


Phe Ile Asp Glu Ala His Ile Thr Gln Ser Leu Thr Trp Leu Ser Gln 
    850                 855                 860                 


Met Gln Lys Asp Asn Gly Cys Phe Arg Ser Ser Gly Ser Leu Leu Asn 
865                 870                 875                 880 


Asn Ala Ile Lys Gly Gly Val Glu Asp Glu Ala Thr Leu Ser Ala Tyr 
                885                 890                 895     


Val Thr Ile Ala Leu Leu Glu Ile Pro Leu Pro Val Thr Asn Pro Ile 
            900                 905                 910         


Val Arg Asn Ala Leu Phe Cys Leu Glu Ser Ala Trp Asn Val Ala Lys 
        915                 920                 925             


Glu Gly Thr His Gly Ser His Val Tyr Thr Lys Ala Leu Leu Ala Tyr 
    930                 935                 940                 


Ala Phe Ser Leu Leu Gly Lys Gln Asn Gln Asn Arg Glu Ile Leu Asn 
945                 950                 955                 960 


Ser Leu Asp Lys Glu Ala Val Lys Glu Asp Asn Leu Val His Trp Glu 
                965                 970                 975     


Arg Pro Gln Arg Pro Lys Ala Pro Val Gly His Leu Tyr Gln Pro Gln 
            980                 985                 990         


Ala Pro Ser Ala Glu Val Glu Met  Thr Ser Tyr Val Leu  Leu Ala Tyr 
        995                 1000                 1005             


Leu Thr  Ala Gln Pro Ala Pro  Thr Ser Gly Asp Leu  Thr Ser Ala 
    1010                 1015                 1020             


Thr Asn  Ile Val Lys Trp Ile  Met Lys Gln Gln Asn  Ala Gln Gly 
    1025                 1030                 1035             


Gly Phe  Ser Ser Thr Gln Asp  Thr Val Val Ala Leu  His Ala Leu 
    1040                 1045                 1050             


Ser Arg  Tyr Gly Ala Ala Thr  Phe Thr Arg Thr Glu  Lys Thr Ala 
    1055                 1060                 1065             


Gln Val  Thr Val Gln Asp Ser  Gln Thr Phe Ser Thr  Asn Phe Gln 
    1070                 1075                 1080             


Val Asp  Asn Asn Asn Leu Leu  Leu Leu Gln Gln Ile  Ser Leu Pro 
    1085                 1090                 1095             


Glu Leu  Pro Gly Glu Tyr Val  Ile Thr Val Thr Gly  Glu Arg Cys 
    1100                 1105                 1110             


Val Tyr  Leu Gln Thr Ser Met  Lys Tyr Asn Ile Leu  Pro Glu Lys 
    1115                 1120                 1125             


Glu Asp  Ser Pro Phe Ala Leu  Lys Val Gln Thr Val  Pro Gln Thr 
    1130                 1135                 1140             


Cys Asp  Gly His Lys Ala His  Thr Ser Phe Gln Ile  Ser Leu Thr 
    1145                 1150                 1155             


Ile Ser  Tyr Thr Gly Asn Arg  Pro Ala Ser Asn Met  Val Ile Val 
    1160                 1165                 1170             


Asp Val  Lys Met Val Ser Gly  Phe Ile Pro Leu Lys  Pro Thr Val 
    1175                 1180                 1185             


Lys Met  Leu Glu Arg Ser Ser  Ser Val Ser Arg Thr  Glu Val Ser 
    1190                 1195                 1200             


Asn Asn  His Val Leu Ile Tyr  Val Glu Gln Val Thr  Asn Gln Thr 
    1205                 1210                 1215             


Leu Ser  Phe Ser Phe Met Val  Leu Gln Asp Ile Pro  Val Gly Asp 
    1220                 1225                 1230             


Leu Lys  Pro Ala Ile Val Lys  Val Tyr Asp Tyr Tyr  Glu Thr Asp 
    1235                 1240                 1245             


Glu Ser  Val Val Ala Glu Tyr  Ile Ala Pro Cys Ser  Thr Asp Thr 
    1250                 1255                 1260             


Glu His  Gly Asn Val 
    1265             


<210>  1141
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  1141

Gln Glu Ala Gln Thr Glu Leu Pro Gln Ala Arg Ile Ser Cys Pro Glu 
1               5                   10                  15      


Gly Thr Asn Ala Tyr Arg Ser Tyr Cys Tyr Tyr Phe Asn Glu Asp Arg 
            20                  25                  30          


Glu Thr Trp Val Asp Ala Asp Leu Tyr Cys Gln Asn Met Asn Ser Gly 
        35                  40                  45              


Asn Leu Val Ser Val Leu Thr Gln Ala Glu Gly Ala Phe Val Ala Ser 
    50                  55                  60                  


Leu Ile Lys Glu Ser Gly Thr Asp Asp Phe Asn Val Trp Ile Gly Leu 
65                  70                  75                  80  


His Asp Pro Lys Lys Asn Arg Arg Trp His Trp Ser Ser Gly Ser Leu 
                85                  90                  95      


Val Ser Tyr Lys Ser Trp Gly Ile Gly Ala Pro Ser Ser Val Asn Pro 
            100                 105                 110         


Gly Tyr Cys Val Ser Leu Thr Ser Ser Thr Gly Phe Gln Lys Trp Lys 
        115                 120                 125             


Asp Val Pro Cys Glu Asp Lys Phe Ser Phe Val Cys Lys Phe Lys Asn 
    130                 135                 140                 


<210>  1142
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  1142

Gln Glu Ser Gln Thr Glu Leu Pro Asn Pro Arg Ile Ser Cys Pro Glu 
1               5                   10                  15      


Gly Thr Asn Ala Tyr Arg Ser Tyr Cys Tyr Tyr Phe Asn Glu Asp Pro 
            20                  25                  30          


Glu Thr Trp Val Asp Ala Asp Leu Tyr Cys Gln Asn Met Asn Ser Gly 
        35                  40                  45              


Asn Leu Val Ser Val Leu Thr Gln Ala Glu Gly Ala Phe Val Ala Ser 
    50                  55                  60                  


Leu Ile Lys Glu Ser Ser Thr Asp Asp Ser Asn Val Trp Ile Gly Leu 
65                  70                  75                  80  


His Asp Pro Lys Lys Asn Arg Arg Trp His Trp Ser Ser Gly Ser Leu 
                85                  90                  95      


Val Ser Tyr Lys Ser Trp Asp Thr Gly Ser Pro Ser Ser Ala Asn Ala 
            100                 105                 110         


Gly Tyr Cys Ala Ser Leu Thr Ser Cys Ser Gly Phe Lys Lys Trp Lys 
        115                 120                 125             


Asp Glu Ser Cys Glu Lys Lys Phe Ser Phe Val Cys Lys Phe Lys Asn 
    130                 135                 140                 


<210>  1143
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  1143

Ile Ser Cys Pro Lys Gly Ser Lys Ala Tyr Gly Ser Pro Cys Tyr Ala 
1               5                   10                  15      


Leu Phe Leu Ser Pro Lys Ser Trp Met Asp Ala Asp Leu Ala Cys Gln 
            20                  25                  30          


Lys Arg Pro Ser Gly Lys Leu Val Ser Val Leu Ser Gly Ala Glu Gly 
        35                  40                  45              


Ser Phe Val Ser Ser Leu Val Arg Ser Ile Ser Asn Ser Tyr Ser Tyr 
    50                  55                  60                  


Ile Trp Ile Gly Leu His Asp Pro Thr Gln Gly Ser Glu Pro Asp Gly 
65                  70                  75                  80  


Asp Gly Trp Glu Trp Ser Ser Thr Asp Val Met Asn Tyr Phe Ala Trp 
                85                  90                  95      


Glu Lys Asn Pro Ser Thr Ile Leu Asn Pro Gly His Cys Gly Ser Leu 
            100                 105                 110         


Ser Arg Ser Thr Gly Phe Leu Lys Trp Lys Asp Tyr Asn Cys Asp Ala 
        115                 120                 125             


Lys Leu Pro Tyr Val Cys Lys Phe Lys Asp 
    130                 135             


<210>  1144
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  1144

Asp Ile Ile Met Arg Pro Ser Cys Ala Pro Gly Trp Phe Tyr His Lys 
1               5                   10                  15      


Ser Asn Cys Tyr Gly Tyr Phe Arg Lys Leu Arg Asn Trp Ser Asp Ala 
            20                  25                  30          


Glu Leu Glu Cys Gln Ser Tyr Gly Asn Gly Ala His Leu Ala Ser Ile 
        35                  40                  45              


Leu Ser Leu Lys Glu Ala Ser Thr Ile Ala Glu Tyr Ile Ser Gly Tyr 
    50                  55                  60                  


Gln Arg Ser Gln Pro Ile Trp Ile Gly Leu His Asp Pro Gln Lys Arg 
65                  70                  75                  80  


Gln Gln Trp Gln Trp Ile Asp Gly Ala Met Tyr Leu Tyr Arg Ser Trp 
                85                  90                  95      


Ser Gly Lys Ser Met Gly Gly Asn Lys His Cys Ala Glu Met Ser Ser 
            100                 105                 110         


Asn Asn Asn Phe Leu Thr Trp Ser Ser Asn Glu Cys Asn Lys Arg Gln 
        115                 120                 125             


His Phe Leu Cys Lys Tyr Arg Pro 
    130                 135     


<210>  1145
<211>  718
<212>  PRT
<213>  Homo Sapiens

<400>  1145

Ser Arg Leu Arg Gln Glu Asp Phe Pro Pro Arg Ile Val Glu His Pro 
1               5                   10                  15      


Ser Asp Val Ile Val Ser Lys Gly Glu Pro Thr Thr Leu Asn Cys Lys 
            20                  25                  30          


Ala Glu Gly Arg Pro Thr Pro Thr Ile Glu Trp Tyr Lys Asp Gly Glu 
        35                  40                  45              


Arg Val Glu Thr Asp Lys Asp Asp Pro Arg Ser His Arg Met Leu Leu 
    50                  55                  60                  


Pro Ser Gly Ser Leu Phe Phe Leu Arg Ile Val His Gly Arg Arg Ser 
65                  70                  75                  80  


Lys Pro Asp Glu Gly Ser Tyr Val Cys Val Ala Arg Asn Tyr Leu Gly 
                85                  90                  95      


Glu Ala Val Ser Arg Asn Ala Ser Leu Glu Val Ala Leu Leu Arg Asp 
            100                 105                 110         


Asp Phe Arg Gln Asn Pro Thr Asp Val Val Val Ala Ala Gly Glu Pro 
        115                 120                 125             


Ala Ile Leu Glu Cys Gln Pro Pro Arg Gly His Pro Glu Pro Thr Ile 
    130                 135                 140                 


Tyr Trp Lys Lys Asp Lys Val Arg Ile Asp Asp Lys Glu Glu Arg Ile 
145                 150                 155                 160 


Ser Ile Arg Gly Gly Lys Leu Met Ile Ser Asn Thr Arg Lys Ser Asp 
                165                 170                 175     


Ala Gly Met Tyr Thr Cys Val Gly Thr Asn Met Val Gly Glu Arg Asp 
            180                 185                 190         


Ser Asp Pro Ala Glu Leu Thr Val Phe Glu Arg Pro Thr Phe Leu Arg 
        195                 200                 205             


Arg Pro Ile Asn Gln Val Val Leu Glu Glu Glu Ala Val Glu Phe Arg 
    210                 215                 220                 


Cys Gln Val Gln Gly Asp Pro Gln Pro Thr Val Arg Trp Lys Lys Asp 
225                 230                 235                 240 


Asp Ala Asp Leu Pro Arg Gly Arg Tyr Asp Ile Lys Asp Asp Tyr Thr 
                245                 250                 255     


Leu Arg Ile Lys Lys Thr Met Ser Thr Asp Glu Gly Thr Tyr Met Cys 
            260                 265                 270         


Ile Ala Glu Asn Arg Val Gly Lys Met Glu Ala Ser Ala Thr Leu Thr 
        275                 280                 285             


Val Arg Ala Arg Pro Val Ala Pro Pro Gln Phe Val Val Arg Pro Arg 
    290                 295                 300                 


Asp Gln Ile Val Ala Gln Gly Arg Thr Val Thr Phe Pro Cys Glu Thr 
305                 310                 315                 320 


Lys Gly Asn Pro Gln Pro Ala Val Phe Trp Gln Lys Glu Gly Ser Gln 
                325                 330                 335     


Asn Leu Leu Phe Pro Asn Gln Pro Gln Gln Pro Asn Ser Arg Cys Ser 
            340                 345                 350         


Val Ser Pro Thr Gly Asp Leu Thr Ile Thr Asn Ile Gln Arg Ser Asp 
        355                 360                 365             


Ala Gly Tyr Tyr Ile Cys Gln Ala Leu Thr Val Ala Gly Ser Ile Leu 
    370                 375                 380                 


Ala Lys Ala Gln Leu Glu Val Thr Asp Val Leu Thr Asp Arg Pro Pro 
385                 390                 395                 400 


Pro Ile Ile Leu Gln Gly Pro Ala Asn Gln Thr Leu Ala Val Asp Gly 
                405                 410                 415     


Thr Ala Leu Leu Lys Cys Lys Ala Thr Gly Asp Pro Leu Pro Val Ile 
            420                 425                 430         


Ser Trp Leu Lys Glu Gly Phe Thr Phe Pro Gly Arg Asp Pro Arg Ala 
        435                 440                 445             


Thr Ile Gln Glu Gln Gly Thr Leu Gln Ile Lys Asn Leu Arg Ile Ser 
    450                 455                 460                 


Asp Thr Gly Thr Tyr Thr Cys Val Ala Thr Ser Ser Ser Gly Glu Thr 
465                 470                 475                 480 


Ser Trp Ser Ala Val Leu Asp Val Thr Glu Ser Gly Ala Thr Ile Ser 
                485                 490                 495     


Lys Asn Tyr Asp Leu Ser Asp Leu Pro Gly Pro Pro Ser Lys Pro Gln 
            500                 505                 510         


Val Thr Asp Val Thr Lys Asn Ser Val Thr Leu Ser Trp Gln Pro Gly 
        515                 520                 525             


Thr Pro Gly Thr Leu Pro Ala Ser Ala Tyr Ile Ile Glu Ala Phe Ser 
    530                 535                 540                 


Gln Ser Val Ser Asn Ser Trp Gln Thr Val Ala Asn His Val Lys Thr 
545                 550                 555                 560 


Thr Leu Tyr Thr Val Arg Gly Leu Arg Pro Asn Thr Ile Tyr Leu Phe 
                565                 570                 575     


Met Val Arg Ala Ile Asn Pro Gln Gly Leu Ser Asp Pro Ser Pro Met 
            580                 585                 590         


Ser Asp Pro Val Arg Thr Gln Asp Ile Ser Pro Pro Ala Gln Gly Val 
        595                 600                 605             


Asp His Arg Gln Val Gln Lys Glu Leu Gly Asp Val Leu Val Arg Leu 
    610                 615                 620                 


His Asn Pro Val Val Leu Thr Pro Thr Thr Val Gln Val Thr Trp Thr 
625                 630                 635                 640 


Val Asp Arg Gln Pro Gln Phe Ile Gln Gly Tyr Arg Val Met Tyr Arg 
                645                 650                 655     


Gln Thr Ser Gly Leu Gln Ala Thr Ser Ser Trp Gln Asn Leu Asp Ala 
            660                 665                 670         


Lys Val Pro Thr Glu Arg Ser Ala Val Leu Val Asn Leu Lys Lys Gly 
        675                 680                 685             


Val Thr Tyr Glu Ile Lys Val Arg Pro Tyr Phe Asn Glu Phe Gln Gly 
    690                 695                 700                 


Met Asp Ser Glu Ser Lys Thr Val Arg Thr Thr Glu Glu Ala 
705                 710                 715             


<210>  1146
<211>  441
<212>  PRT
<213>  Homo Sapiens

<400>  1146

Gln Asp Ser Pro Pro Gln Ile Leu Val His Pro Gln Asp Gln Leu Phe 
1               5                   10                  15      


Gln Gly Pro Gly Pro Ala Arg Met Ser Cys Gln Ala Ser Gly Gln Pro 
            20                  25                  30          


Pro Pro Thr Ile Arg Trp Leu Leu Asn Gly Gln Pro Leu Ser Met Val 
        35                  40                  45              


Pro Pro Asp Pro His His Leu Leu Pro Asp Gly Thr Leu Leu Leu Leu 
    50                  55                  60                  


Gln Pro Pro Ala Arg Gly His Ala His Asp Gly Gln Ala Leu Ser Thr 
65                  70                  75                  80  


Asp Leu Gly Val Tyr Thr Cys Glu Ala Ser Asn Arg Leu Gly Thr Ala 
                85                  90                  95      


Val Ser Arg Gly Ala Arg Leu Ser Val Ala Val Leu Arg Glu Asp Phe 
            100                 105                 110         


Gln Ile Gln Pro Arg Asp Met Val Ala Val Val Gly Glu Gln Phe Thr 
        115                 120                 125             


Leu Glu Cys Gly Pro Pro Trp Gly His Pro Glu Pro Thr Val Ser Trp 
    130                 135                 140                 


Trp Lys Asp Gly Lys Pro Leu Ala Leu Gln Pro Gly Arg His Thr Val 
145                 150                 155                 160 


Ser Gly Gly Ser Leu Leu Met Ala Arg Ala Glu Lys Ser Asp Glu Gly 
                165                 170                 175     


Thr Tyr Met Cys Val Ala Thr Asn Ser Ala Gly His Arg Glu Ser Arg 
            180                 185                 190         


Ala Ala Arg Val Ser Ile Gln Glu Pro Gln Asp Tyr Thr Glu Pro Val 
        195                 200                 205             


Glu Leu Leu Ala Val Arg Ile Gln Leu Glu Asn Val Thr Leu Leu Asn 
    210                 215                 220                 


Pro Asp Pro Ala Glu Gly Pro Lys Pro Arg Pro Ala Val Trp Leu Ser 
225                 230                 235                 240 


Trp Lys Val Ser Gly Pro Ala Ala Pro Ala Gln Ser Tyr Thr Ala Leu 
                245                 250                 255     


Phe Arg Thr Gln Thr Ala Pro Gly Gly Gln Gly Ala Pro Trp Ala Glu 
            260                 265                 270         


Glu Leu Leu Ala Gly Trp Gln Ser Ala Glu Leu Gly Gly Leu His Trp 
        275                 280                 285             


Gly Gln Asp Tyr Glu Phe Lys Val Arg Pro Ser Ser Gly Arg Ala Arg 
    290                 295                 300                 


Gly Pro Asp Ser Asn Val Leu Leu Leu Arg Leu Pro Glu Lys Val Pro 
305                 310                 315                 320 


Ser Ala Pro Pro Gln Glu Val Thr Leu Lys Pro Gly Asn Gly Thr Val 
                325                 330                 335     


Phe Val Ser Trp Val Pro Pro Pro Ala Glu Asn His Asn Gly Ile Ile 
            340                 345                 350         


Arg Gly Tyr Gln Val Trp Ser Leu Gly Asn Thr Ser Leu Pro Pro Ala 
        355                 360                 365             


Asn Trp Thr Val Val Gly Glu Gln Thr Gln Leu Glu Ile Ala Thr His 
    370                 375                 380                 


Met Pro Gly Ser Tyr Cys Val Gln Val Ala Ala Val Thr Gly Ala Gly 
385                 390                 395                 400 


Ala Gly Glu Pro Ser Arg Pro Val Cys Leu Leu Leu Glu Gln Ala Met 
                405                 410                 415     


Glu Arg Ala Thr Gln Glu Pro Ser Glu His Gly Pro Trp Thr Leu Glu 
            420                 425                 430         


Gln Leu Arg Ala Thr Leu Lys Arg Pro 
        435                 440     


<210>  1147
<211>  364
<212>  PRT
<213>  Homo Sapiens

<400>  1147

Gln Glu Thr Glu Leu Ser Val Ser Ala Glu Leu Val Pro Thr Ser Ser 
1               5                   10                  15      


Trp Asn Ile Ser Ser Glu Leu Asn Lys Asp Ser Tyr Leu Thr Leu Asp 
            20                  25                  30          


Glu Pro Met Asn Asn Ile Thr Thr Ser Leu Gly Gln Thr Ala Glu Leu 
        35                  40                  45              


His Cys Lys Val Ser Gly Asn Pro Pro Pro Thr Ile Arg Trp Phe Lys 
    50                  55                  60                  


Asn Asp Ala Pro Val Val Gln Glu Pro Arg Arg Leu Ser Phe Arg Ser 
65                  70                  75                  80  


Thr Ile Tyr Gly Ser Arg Leu Arg Ile Arg Asn Leu Asp Thr Thr Asp 
                85                  90                  95      


Thr Gly Tyr Phe Gln Cys Val Ala Thr Asn Gly Lys Glu Val Val Ser 
            100                 105                 110         


Ser Thr Gly Val Leu Phe Val Lys Phe Gly Pro Pro Pro Thr Ala Ser 
        115                 120                 125             


Pro Gly Tyr Ser Asp Glu Tyr Glu Glu Asp Gly Phe Cys Gln Pro Tyr 
    130                 135                 140                 


Arg Gly Ile Ala Cys Ala Arg Phe Ile Gly Asn Arg Thr Val Tyr Met 
145                 150                 155                 160 


Glu Ser Leu His Met Gln Gly Glu Ile Glu Asn Gln Ile Thr Ala Ala 
                165                 170                 175     


Phe Thr Met Ile Gly Thr Ser Ser His Leu Ser Asp Lys Cys Ser Gln 
            180                 185                 190         


Phe Ala Ile Pro Ser Leu Cys His Tyr Ala Phe Pro Tyr Cys Asp Glu 
        195                 200                 205             


Thr Ser Ser Val Pro Lys Pro Arg Asp Leu Cys Arg Asp Glu Cys Glu 
    210                 215                 220                 


Ile Leu Glu Asn Val Leu Cys Gln Thr Glu Tyr Ile Phe Ala Arg Ser 
225                 230                 235                 240 


Asn Pro Met Ile Leu Met Arg Leu Lys Leu Pro Asn Cys Glu Asp Leu 
                245                 250                 255     


Pro Gln Pro Glu Ser Pro Glu Ala Ala Asn Cys Ile Arg Ile Gly Ile 
            260                 265                 270         


Pro Met Ala Asp Pro Ile Asn Lys Asn His Lys Cys Tyr Asn Ser Thr 
        275                 280                 285             


Gly Val Asp Tyr Arg Gly Thr Val Ser Val Thr Lys Ser Gly Arg Gln 
    290                 295                 300                 


Cys Gln Pro Trp Asn Ser Gln Tyr Pro His Thr His Thr Phe Thr Ala 
305                 310                 315                 320 


Leu Arg Phe Pro Glu Leu Asn Gly Gly His Ser Tyr Cys Arg Asn Pro 
                325                 330                 335     


Gly Asn Gln Lys Glu Ala Pro Trp Cys Phe Thr Leu Asp Glu Asn Phe 
            340                 345                 350         


Lys Ser Asp Leu Cys Asp Ile Pro Ala Cys Gly Lys 
        355                 360                 


<210>  1148
<211>  370
<212>  PRT
<213>  Homo Sapiens

<400>  1148

Glu Val Glu Val Leu Asp Pro Asn Asp Pro Leu Gly Pro Leu Asp Gly 
1               5                   10                  15      


Gln Asp Gly Pro Ile Pro Thr Leu Lys Gly Tyr Phe Leu Asn Phe Leu 
            20                  25                  30          


Glu Pro Val Asn Asn Ile Thr Ile Val Gln Gly Gln Thr Ala Ile Leu 
        35                  40                  45              


His Cys Lys Val Ala Gly Asn Pro Pro Pro Asn Val Arg Trp Leu Lys 
    50                  55                  60                  


Asn Asp Ala Pro Val Val Gln Glu Pro Arg Arg Ile Ile Ile Arg Lys 
65                  70                  75                  80  


Thr Glu Tyr Gly Ser Arg Leu Arg Ile Gln Asp Leu Asp Thr Thr Asp 
                85                  90                  95      


Thr Gly Tyr Tyr Gln Cys Val Ala Thr Asn Gly Met Lys Thr Ile Thr 
            100                 105                 110         


Ala Thr Gly Val Leu Phe Val Arg Leu Gly Pro Thr His Ser Pro Asn 
        115                 120                 125             


His Asn Phe Gln Asp Asp Tyr His Glu Asp Gly Phe Cys Gln Pro Tyr 
    130                 135                 140                 


Arg Gly Ile Ala Cys Ala Arg Phe Ile Gly Asn Arg Thr Ile Tyr Val 
145                 150                 155                 160 


Asp Ser Leu Gln Met Gln Gly Glu Ile Glu Asn Arg Ile Thr Ala Ala 
                165                 170                 175     


Phe Thr Met Ile Gly Thr Ser Thr His Leu Ser Asp Gln Cys Ser Gln 
            180                 185                 190         


Phe Ala Ile Pro Ser Phe Cys His Phe Val Phe Pro Leu Cys Asp Ala 
        195                 200                 205             


Arg Ser Arg Ala Pro Lys Pro Arg Glu Leu Cys Arg Asp Glu Cys Glu 
    210                 215                 220                 


Val Leu Glu Ser Asp Leu Cys Arg Gln Glu Tyr Thr Ile Ala Arg Ser 
225                 230                 235                 240 


Asn Pro Leu Ile Leu Met Arg Leu Gln Leu Pro Lys Cys Glu Ala Leu 
                245                 250                 255     


Pro Met Pro Glu Ser Pro Asp Ala Ala Asn Cys Met Arg Ile Gly Ile 
            260                 265                 270         


Pro Ala Glu Arg Leu Gly Arg Tyr His Gln Cys Tyr Asn Gly Ser Gly 
        275                 280                 285             


Met Asp Tyr Arg Gly Thr Ala Ser Thr Thr Lys Ser Gly His Gln Cys 
    290                 295                 300                 


Gln Pro Trp Ala Leu Gln His Pro His Ser His His Leu Ser Ser Thr 
305                 310                 315                 320 


Asp Phe Pro Glu Leu Gly Gly Gly His Ala Tyr Cys Arg Asn Pro Gly 
                325                 330                 335     


Gly Gln Met Glu Gly Pro Trp Cys Phe Thr Gln Asn Lys Asn Val Arg 
            340                 345                 350         


Met Glu Leu Cys Asp Val Pro Ser Cys Ser Pro Arg Asp Ser Ser Lys 
        355                 360                 365             


Met Gly 
    370 


<210>  1149
<211>  258
<212>  PRT
<213>  Homo Sapiens

<400>  1149

Thr Val Leu Asn Ser Cys Leu Lys Ser Cys Val Thr Asn Leu Gly Gln 
1               5                   10                  15      


Gln Leu Asp Leu Gly Thr Pro His Asn Leu Ser Glu Pro Cys Ile Gln 
            20                  25                  30          


Gly Cys His Phe Trp Asn Ser Val Asp Gln Lys Asn Cys Ala Leu Lys 
        35                  40                  45              


Cys Arg Glu Ser Cys Glu Val Gly Cys Ser Ser Ala Glu Gly Ala Tyr 
    50                  55                  60                  


Glu Glu Glu Val Leu Glu Asn Ala Asp Leu Pro Thr Ala Pro Phe Ala 
65                  70                  75                  80  


Ser Ser Ile Gly Ser His Asn Met Thr Leu Arg Trp Lys Ser Ala Asn 
                85                  90                  95      


Phe Ser Gly Val Lys Tyr Ile Ile Gln Trp Lys Tyr Ala Gln Leu Leu 
            100                 105                 110         


Gly Ser Trp Thr Tyr Thr Lys Thr Val Ser Arg Pro Ser Tyr Val Val 
        115                 120                 125             


Lys Pro Leu His Pro Phe Thr Glu Tyr Ile Phe Arg Val Val Trp Ile 
    130                 135                 140                 


Phe Thr Ala Gln Leu Gln Leu Tyr Ser Pro Pro Ser Pro Ser Tyr Arg 
145                 150                 155                 160 


Thr His Pro His Gly Val Pro Glu Thr Ala Pro Leu Ile Arg Asn Ile 
                165                 170                 175     


Glu Ser Ser Ser Pro Asp Thr Val Glu Val Ser Trp Asp Pro Pro Gln 
            180                 185                 190         


Phe Pro Gly Gly Pro Ile Leu Gly Tyr Asn Leu Arg Leu Ile Ser Lys 
        195                 200                 205             


Asn Gln Lys Leu Asp Ala Gly Thr Gln Arg Thr Ser Phe Gln Phe Tyr 
    210                 215                 220                 


Ser Thr Leu Pro Asn Thr Ile Tyr Arg Phe Ser Ile Ala Ala Val Asn 
225                 230                 235                 240 


Glu Val Gly Glu Gly Pro Glu Ala Glu Ser Ser Ile Thr Thr Ser Ser 
                245                 250                 255     


Ser Ala 
        


<210>  1150
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  1150

Cys Pro Gly Ala Cys Val Cys Tyr Asn Glu Pro Lys Val Thr Thr Ser 
1               5                   10                  15      


Cys Pro Gln Gln Gly Leu Gln Ala Val Pro Val Gly Ile Pro Ala Ala 
            20                  25                  30          


Ser Gln Arg Ile Phe Leu His Gly Asn Arg Ile Ser His Val Pro Ala 
        35                  40                  45              


Ala Ser Phe Arg Ala Cys Arg Asn Leu Thr Ile Leu Trp Leu His Ser 
    50                  55                  60                  


Asn Val Leu Ala Arg Ile Asp Ala Ala Ala Phe Thr Gly Leu Ala Leu 
65                  70                  75                  80  


Leu Glu Gln Leu Asp Leu Ser Asp Asn Ala Gln Leu Arg Ser Val Asp 
                85                  90                  95      


Pro Ala Thr Phe His Gly Leu Gly Arg Leu His Thr Leu His Leu Asp 
            100                 105                 110         


Arg Cys Gly Leu Gln Glu Leu Gly Pro Gly Leu Phe Arg Gly Leu Ala 
        115                 120                 125             


Ala Leu Gln Tyr Leu Tyr Leu Gln Asp Asn Ala Leu Gln Ala Leu Pro 
    130                 135                 140                 


Asp Asp Thr Phe Arg Asp Leu Gly Asn Leu Thr His Leu Phe Leu His 
145                 150                 155                 160 


Gly Asn Arg Ile Ser Ser Val Pro Glu Arg Ala Phe Arg Gly Leu His 
                165                 170                 175     


Ser Leu Asp Arg Leu Leu Leu His Gln Asn Arg Val Ala His Val His 
            180                 185                 190         


Pro His Ala Phe Arg Asp Leu Gly Arg Leu Met Thr Leu Tyr Leu Phe 
        195                 200                 205             


Ala Asn Asn Leu Ser Ala Leu Pro Thr Glu Ala Leu Ala Pro Leu Arg 
    210                 215                 220                 


Ala Leu Gln Tyr Leu Arg Leu Asn Asp Asn Pro Trp Val Cys Asp Cys 
225                 230                 235                 240 


Arg Ala Arg Pro Leu Trp Ala Trp Leu Gln Lys Phe Arg Gly Ser Ser 
                245                 250                 255     


Ser Glu Val Pro Cys Ser Leu Pro Gln Arg Leu Ala Gly Arg Asp Leu 
            260                 265                 270         


Lys Arg Leu Ala Ala Asn Asp Leu Gln Gly Cys Ala Val Ala Thr Gly 
        275                 280                 285             


Pro Tyr His Pro Ile Trp Thr Gly Arg Ala Thr Asp Glu Glu Pro Leu 
    290                 295                 300                 


Gly Leu Pro Lys Cys Cys Gln Pro Asp Ala Ala Asp Lys Ala Ser Val 
305                 310                 315                 320 


Leu Glu Pro Gly Arg Pro Ala Ser Ala Gly Asn Ala Leu Lys Gly Arg 
                325                 330                 335     


Val Pro Pro Gly Asp Ser Pro Pro Gly Asn Gly Ser Gly Pro Arg His 
            340                 345                 350         


Ile Asn Asp Ser Pro Phe Gly Thr Leu Pro Gly Ser Ala Glu Pro Pro 
        355                 360                 365             


Leu Thr Ala Val Arg Pro Glu Gly Ser Glu Pro Pro Gly Phe Pro Thr 
    370                 375                 380                 


Ser Gly Pro Arg Arg Arg Pro Gly Cys Ser Arg Lys Asn Arg Thr Arg 
385                 390                 395                 400 


Ser His Cys Arg Leu Gly Gln Ala Gly Ser Gly Gly Gly Gly Thr Gly 
                405                 410                 415     


Asp Ser Glu Gly Ser 
            420     


<210>  1151
<211>  396
<212>  PRT
<213>  Homo Sapiens

<400>  1151

Cys Pro Arg Asp Cys Val Cys Tyr Pro Ala Pro Met Thr Val Ser Cys 
1               5                   10                  15      


Gln Ala His Asn Phe Ala Ala Ile Pro Glu Gly Ile Pro Val Asp Ser 
            20                  25                  30          


Glu Arg Val Phe Leu Gln Asn Asn Arg Ile Gly Leu Leu Gln Pro Gly 
        35                  40                  45              


His Phe Ser Pro Ala Met Val Thr Leu Trp Ile Tyr Ser Asn Asn Ile 
    50                  55                  60                  


Thr Tyr Ile His Pro Ser Thr Phe Glu Gly Phe Val His Leu Glu Glu 
65                  70                  75                  80  


Leu Asp Leu Gly Asp Asn Arg Gln Leu Arg Thr Leu Ala Pro Glu Thr 
                85                  90                  95      


Phe Gln Gly Leu Val Lys Leu His Ala Leu Tyr Leu Tyr Lys Cys Gly 
            100                 105                 110         


Leu Ser Ala Leu Pro Ala Gly Val Phe Gly Gly Leu His Ser Leu Gln 
        115                 120                 125             


Tyr Leu Tyr Leu Gln Asp Asn His Ile Glu Tyr Leu Gln Asp Asp Ile 
    130                 135                 140                 


Phe Val Asp Leu Val Asn Leu Ser His Leu Phe Leu His Gly Asn Lys 
145                 150                 155                 160 


Leu Trp Ser Leu Gly Pro Gly Thr Phe Arg Gly Leu Val Asn Leu Asp 
                165                 170                 175     


Arg Leu Leu Leu His Glu Asn Gln Leu Gln Trp Val His His Lys Ala 
            180                 185                 190         


Phe His Asp Leu Arg Arg Leu Thr Thr Leu Phe Leu Phe Asn Asn Ser 
        195                 200                 205             


Leu Ser Glu Leu Gln Gly Glu Cys Leu Ala Pro Leu Gly Ala Leu Glu 
    210                 215                 220                 


Phe Leu Arg Leu Asn Gly Asn Pro Trp Asp Cys Gly Cys Arg Ala Arg 
225                 230                 235                 240 


Ser Leu Trp Glu Trp Leu Gln Arg Phe Arg Gly Ser Ser Ser Ala Val 
                245                 250                 255     


Pro Cys Val Ser Pro Gly Leu Arg His Gly Gln Asp Leu Lys Leu Leu 
            260                 265                 270         


Arg Ala Glu Asp Phe Arg Asn Cys Thr Gly Pro Ala Ser Pro His Gln 
        275                 280                 285             


Ile Lys Ser His Thr Leu Thr Thr Thr Asp Arg Ala Ala Arg Lys Glu 
    290                 295                 300                 


His His Ser Pro His Gly Pro Thr Arg Ser Lys Gly His Pro His Gly 
305                 310                 315                 320 


Pro Arg Pro Gly His Arg Lys Pro Gly Lys Asn Cys Thr Asn Pro Arg 
                325                 330                 335     


Asn Arg Asn Gln Ile Ser Lys Ala Gly Ala Gly Lys Gln Ala Pro Glu 
            340                 345                 350         


Leu Pro Asp Tyr Ala Pro Asp Tyr Gln His Lys Phe Ser Phe Asp Ile 
        355                 360                 365             


Met Pro Thr Ala Arg Pro Lys Arg Lys Gly Lys Cys Ala Arg Arg Thr 
    370                 375                 380                 


Pro Ile Arg Ala Pro Ser Gly Val Gln Gln Ala Ser 
385                 390                 395     


<210>  1152
<211>  344
<212>  PRT
<213>  Homo Sapiens

<400>  1152

Gln Ala Asn Asn Phe Ser Ser Val Pro Leu Ser Leu Pro Pro Ser Thr 
1               5                   10                  15      


Gln Arg Leu Phe Leu Gln Asn Asn Leu Ile Arg Thr Leu Arg Pro Gly 
            20                  25                  30          


Thr Phe Gly Ser Asn Leu Leu Thr Leu Trp Leu Phe Ser Asn Asn Leu 
        35                  40                  45              


Ser Thr Ile Tyr Pro Gly Thr Phe Arg His Leu Gln Ala Leu Glu Glu 
    50                  55                  60                  


Leu Asp Leu Gly Asp Asn Arg His Leu Arg Ser Leu Glu Pro Asp Thr 
65                  70                  75                  80  


Phe Gln Gly Leu Glu Arg Leu Gln Ser Leu His Leu Tyr Arg Cys Gln 
                85                  90                  95      


Leu Ser Ser Leu Pro Gly Asn Ile Phe Arg Gly Leu Val Ser Leu Gln 
            100                 105                 110         


Tyr Leu Tyr Leu Gln Glu Asn Ser Leu Leu His Leu Gln Asp Asp Leu 
        115                 120                 125             


Phe Ala Asp Leu Ala Asn Leu Ser His Leu Phe Leu His Gly Asn Arg 
    130                 135                 140                 


Leu Arg Leu Leu Thr Glu His Val Phe Arg Gly Leu Gly Ser Leu Asp 
145                 150                 155                 160 


Arg Leu Leu Leu His Gly Asn Arg Leu Gln Gly Val His Arg Ala Ala 
                165                 170                 175     


Phe Arg Gly Leu Ser Arg Leu Thr Ile Leu Tyr Leu Phe Asn Asn Ser 
            180                 185                 190         


Leu Ala Ser Leu Pro Gly Glu Ala Leu Ala Asp Leu Pro Ser Leu Glu 
        195                 200                 205             


Phe Leu Arg Leu Asn Ala Asn Pro Trp Ala Cys Asp Cys Arg Ala Arg 
    210                 215                 220                 


Pro Leu Trp Ala Trp Phe Gln Arg Ala Arg Val Ser Ser Ser Asp Val 
225                 230                 235                 240 


Thr Cys Ala Thr Pro Pro Glu Arg Gln Gly Arg Asp Leu Arg Ala Leu 
                245                 250                 255     


Arg Glu Ala Asp Phe Gln Ala Cys Pro Pro Ala Ala Pro Thr Arg Pro 
            260                 265                 270         


Gly Ser Arg Ala Arg Gly Asn Ser Ser Ser Asn His Leu Tyr Gly Val 
        275                 280                 285             


Ala Glu Ala Gly Ala Pro Pro Ala Asp Pro Ser Thr Leu Tyr Arg Asp 
    290                 295                 300                 


Leu Pro Ala Glu Asp Ser Arg Gly Arg Gln Gly Gly Asp Ala Pro Thr 
305                 310                 315                 320 


Glu Asp Asp Tyr Trp Gly Gly Tyr Gly Gly Glu Asp Gln Arg Gly Glu 
                325                 330                 335     


Gln Met Cys Pro Gly Ala Ala Cys 
            340                 


<210>  1153
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  1153

Met Thr Ser Gly Ser Val Phe Phe Tyr Ile Leu Ile Phe Gly Lys Tyr 
1               5                   10                  15      


Phe Ser His Gly Gly Gly Gln Asp Val Lys Cys Ser Leu Gly Tyr Phe 
            20                  25                  30          


Pro Cys Gly Asn Ile Thr Lys Cys Leu Pro Gln Leu Leu His Cys Asn 
        35                  40                  45              


Gly Val Asp Asp Cys Gly Asn Gln Ala Asp Glu Asp Asn Cys Gly Asp 
    50                  55                  60                  


Asn Asn Gly Trp Ser Leu Gln Phe Asp Lys Tyr Phe Ala Ser Tyr Tyr 
65                  70                  75                  80  


Lys Met Thr Ser Gln Tyr Pro Phe Glu Ala Glu Thr Pro Glu Cys Leu 
                85                  90                  95      


Val Gly Ser Val Pro Val Gln Cys Leu Cys Gln Gly Leu Glu Leu Asp 
            100                 105                 110         


Cys Asp Glu Thr Asn Leu Arg Ala Val Pro Ser Val Ser Ser Asn Val 
        115                 120                 125             


Thr Ala Met Ser Leu Gln Trp Asn Leu Ile Arg Lys Leu Pro Pro Asp 
    130                 135                 140                 


Cys Phe Lys Asn Tyr His Asp Leu Gln Lys Leu Tyr Leu Gln Asn Asn 
145                 150                 155                 160 


Lys Ile Thr Ser Ile Ser Ile Tyr Ala Phe Arg Gly Leu Asn Ser Leu 
                165                 170                 175     


Thr Lys Leu Tyr Leu Ser His Asn Arg Ile Thr Phe Leu Lys Pro Gly 
            180                 185                 190         


Val Phe Glu Asp Leu His Arg Leu Glu Trp Leu Ile Ile Glu Asp Asn 
        195                 200                 205             


His Leu Ser Arg Ile Ser Pro Pro Thr Phe Tyr Gly Leu Asn Ser Leu 
    210                 215                 220                 


Ile Leu Leu Val Leu Met Asn Asn Val Leu Thr Arg Leu Pro Asp Lys 
225                 230                 235                 240 


Pro Leu Cys Gln His Met Pro Arg Leu His Trp Leu Asp Leu Glu Gly 
                245                 250                 255     


Asn His Ile His Asn Leu Arg Asn Leu Thr Phe Ile Ser Cys Ser Asn 
            260                 265                 270         


Leu Thr Val Leu Val Met Arg Lys Asn Lys Ile Asn His Leu Asn Glu 
        275                 280                 285             


Asn Thr Phe Ala Pro Leu Gln Lys Leu Asp Glu Leu Asp Leu Gly Ser 
    290                 295                 300                 


Asn Lys Ile Glu Asn Leu Pro Pro Leu Ile Phe Lys Asp Leu Lys Glu 
305                 310                 315                 320 


Leu Ser Gln Leu Asn Leu Ser Tyr Asn Pro Ile Gln Lys Ile Gln Ala 
                325                 330                 335     


Asn Gln Phe Asp Tyr Leu Val Lys Leu Lys Ser Leu Ser Leu Glu Gly 
            340                 345                 350         


Ile Glu Ile Ser Asn Ile Gln Gln Arg Met Phe Arg Pro Leu Met Asn 
        355                 360                 365             


Leu Ser His Ile Tyr Phe Lys Lys Phe Gln Tyr Cys Gly Tyr Ala Pro 
    370                 375                 380                 


His Val Arg Ser Cys Lys Pro Asn Thr Asp Gly Ile Ser Ser Leu Glu 
385                 390                 395                 400 


Asn Leu Leu Ala Ser Ile Ile Gln Arg 
                405                 


<210>  1154
<211>  389
<212>  PRT
<213>  Homo Sapiens

<400>  1154

Arg Lys Val Asp Ser Leu Ser Glu Asp Ile Ser Leu Thr Gln Ser Ile 
1               5                   10                  15      


Tyr Asp Lys Lys Leu Val Leu Met Gln Lys Asn Leu Gln Gly Leu Asp 
            20                  25                  30          


Pro Lys Ala Leu Asn Asn Cys Ser Phe Cys His Glu Ala Gly Gln Leu 
        35                  40                  45              


Gly Pro Glu Ile Arg Lys Leu Gln Glu Glu Leu Glu Gly Ile Gln Lys 
    50                  55                  60                  


Leu Leu Leu Ala Gln Glu Val Gln Leu Asp Gln Thr Leu Gln Ala Gln 
65                  70                  75                  80  


Glu Val Leu Ser Thr Thr Ser Arg Gln Ile Ser Gln Glu Met Gly Ser 
                85                  90                  95      


Cys Ser Phe Ser Ile His Gln Val Asn Gln Ser Leu Gly Leu Phe Leu 
            100                 105                 110         


Ala Gln Val Arg Gly Trp Gln Ala Thr Thr Ala Gly Leu Asp Leu Ser 
        115                 120                 125             


Leu Lys Asp Leu Thr Gln Glu Cys Tyr Asp Val Lys Ala Ala Val His 
    130                 135                 140                 


Gln Ile Asn Phe Thr Val Gly Gln Thr Ser Glu Trp Ile His Gly Ile 
145                 150                 155                 160 


Gln Arg Lys Thr Asp Glu Glu Thr Leu Thr Leu Gln Lys Ile Val Thr 
                165                 170                 175     


Asp Trp Gln Asn Tyr Thr Arg Leu Phe Ser Gly Leu Arg Thr Thr Ser 
            180                 185                 190         


Thr Lys Thr Gly Glu Ala Val Lys Asn Ile Gln Ala Thr Leu Gly Ala 
        195                 200                 205             


Ser Ser Gln Arg Ile Ser Gln Asn Ser Glu Ser Met His Asp Leu Val 
    210                 215                 220                 


Leu Gln Val Met Gly Leu Gln Leu Gln Leu Asp Asn Ile Ser Ser Phe 
225                 230                 235                 240 


Leu Asp Asp His Glu Glu Asn Met His Asp Leu Gln Tyr His Thr His 
                245                 250                 255     


Tyr Ala Gln Asn Arg Thr Val Glu Arg Phe Glu Ser Leu Glu Gly Arg 
            260                 265                 270         


Met Ala Ser His Glu Ile Glu Ile Gly Thr Ile Phe Thr Asn Ile Asn 
        275                 280                 285             


Ala Thr Asp Asn His Val His Ser Met Leu Lys Tyr Leu Asp Asp Val 
    290                 295                 300                 


Arg Leu Ser Cys Thr Leu Gly Phe His Thr His Ala Glu Glu Leu Tyr 
305                 310                 315                 320 


Tyr Leu Asn Lys Ser Val Ser Ile Met Leu Gly Thr Thr Asp Leu Leu 
                325                 330                 335     


Arg Glu Arg Phe Ser Leu Leu Ser Ala Arg Leu Asp Leu Asn Val Arg 
            340                 345                 350         


Asn Leu Ser Met Ile Val Glu Glu Met Lys Ala Val Asp Thr Gln His 
        355                 360                 365             


Gly Glu Ile Leu Arg Asn Val Thr Ile Leu Arg Gly His Thr Leu Phe 
    370                 375                 380                 


Ser His Asn Arg Ile 
385                 


<210>  1155
<211>  402
<212>  PRT
<213>  Homo Sapiens

<400>  1155

Ser Glu Leu Asp Pro Lys Gly Gln His Val Cys Val Ala Ser Ser Pro 
1               5                   10                  15      


Ser Ala Glu Leu Gln Cys Cys Ala Gly Trp Arg Gln Lys Asp Gln Glu 
            20                  25                  30          


Cys Thr Ile Pro Ile Cys Glu Gly Pro Asp Ala Cys Gln Lys Asp Glu 
        35                  40                  45              


Val Cys Val Lys Pro Gly Leu Cys Arg Cys Lys Pro Gly Phe Phe Gly 
    50                  55                  60                  


Ala His Cys Ser Ser Arg Cys Pro Gly Gln Tyr Trp Gly Pro Asp Cys 
65                  70                  75                  80  


Arg Glu Ser Cys Pro Cys His Pro His Gly Gln Cys Glu Pro Ala Thr 
                85                  90                  95      


Gly Ala Cys Gln Cys Gln Ala Asp Arg Trp Gly Ala Arg Cys Glu Phe 
            100                 105                 110         


Pro Cys Ala Cys Gly Pro His Gly Arg Cys Asp Pro Ala Thr Gly Val 
        115                 120                 125             


Cys His Cys Glu Pro Gly Trp Trp Ser Ser Thr Cys Arg Arg Pro Cys 
    130                 135                 140                 


Gln Cys Asn Thr Ala Ala Ala Arg Cys Glu Gln Ala Thr Gly Ala Cys 
145                 150                 155                 160 


Val Cys Lys Pro Gly Trp Trp Gly Arg Arg Cys Ser Phe Arg Cys Asn 
                165                 170                 175     


Cys His Gly Ser Pro Cys Glu Gln Asp Ser Gly Arg Cys Ala Cys Arg 
            180                 185                 190         


Pro Gly Trp Trp Gly Pro Glu Cys Gln Gln Gln Cys Glu Cys Val Arg 
        195                 200                 205             


Gly Arg Cys Ser Ala Ala Ser Gly Glu Cys Thr Cys Pro Pro Gly Phe 
    210                 215                 220                 


Arg Gly Ala Arg Cys Glu Leu Pro Cys Pro Ala Gly Ser His Gly Val 
225                 230                 235                 240 


Gln Cys Ala His Ser Cys Gly Arg Cys Lys His Asn Glu Pro Cys Ser 
                245                 250                 255     


Pro Asp Thr Gly Ser Cys Glu Ser Cys Glu Pro Gly Trp Asn Gly Thr 
            260                 265                 270         


Gln Cys Gln Gln Pro Cys Leu Pro Gly Thr Phe Gly Glu Ser Cys Glu 
        275                 280                 285             


Gln Gln Cys Pro His Cys Arg His Gly Glu Ala Cys Glu Pro Asp Thr 
    290                 295                 300                 


Gly His Cys Gln Arg Cys Asp Pro Gly Trp Leu Gly Pro Arg Cys Glu 
305                 310                 315                 320 


Asp Pro Cys Pro Thr Gly Thr Phe Gly Glu Asp Cys Gly Ser Thr Cys 
                325                 330                 335     


Pro Thr Cys Val Gln Gly Ser Cys Asp Thr Val Thr Gly Asp Cys Val 
            340                 345                 350         


Cys Ser Ala Gly Tyr Trp Gly Pro Ser Cys Asn Ala Ser Cys Pro Ala 
        355                 360                 365             


Gly Phe His Gly Asn Asn Cys Ser Val Pro Cys Glu Cys Pro Glu Gly 
    370                 375                 380                 


Leu Cys His Pro Val Ser Gly Ser Cys Gln Pro Gly Ser Gly Ser Arg 
385                 390                 395                 400 


Asp Thr 
        


<210>  1156
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  1156

Gln Glu Leu Asn Pro Arg Gly Arg Asn Val Cys Arg Ala Pro Gly Ser 
1               5                   10                  15      


Gln Val Pro Thr Cys Cys Ala Gly Trp Arg Gln Gln Gly Asp Glu Cys 
            20                  25                  30          


Gly Ile Ala Val Cys Glu Gly Asn Ser Thr Cys Ser Glu Asn Glu Val 
        35                  40                  45              


Cys Val Arg Pro Gly Glu Cys Arg Cys Arg His Gly Tyr Phe Gly Ala 
    50                  55                  60                  


Asn Cys Asp Thr Lys Cys Pro Arg Gln Phe Trp Gly Pro Asp Cys Lys 
65                  70                  75                  80  


Glu Leu Cys Ser Cys His Pro His Gly Gln Cys Glu Asp Val Thr Gly 
                85                  90                  95      


Gln Cys Thr Cys His Ala Arg Arg Trp Gly Ala Arg Cys Glu His Ala 
            100                 105                 110         


Cys Gln Cys Gln His Gly Thr Cys His Pro Arg Ser Gly Ala Cys Arg 
        115                 120                 125             


Cys Glu Pro Gly Trp Trp Gly Ala Gln Cys Ala Ser Ala Cys Tyr Cys 
    130                 135                 140                 


Ser Ala Thr Ser Arg Cys Asp Pro Gln Thr Gly Ala Cys Leu Cys His 
145                 150                 155                 160 


Ala Gly Trp Trp Gly Arg Ser Cys Asn Asn Gln Cys Ala Cys Asn Ser 
                165                 170                 175     


Ser Pro Cys Glu Gln Gln Ser Gly Arg Cys Gln Cys Arg Glu Arg Thr 
            180                 185                 190         


Phe Gly Ala Arg Cys Asp Arg Tyr Cys Gln Cys Phe Arg Gly Arg Cys 
        195                 200                 205             


His Pro Val Asp Gly Thr Cys Ala Cys Glu Pro Gly Tyr Arg Gly Lys 
    210                 215                 220                 


Tyr Cys Arg Glu Pro Cys Pro Ala Gly Phe Tyr Gly Leu Gly Cys Arg 
225                 230                 235                 240 


Arg Arg Cys Gly Gln Cys Lys Gly Gln Gln Pro Cys Thr Val Ala Glu 
                245                 250                 255     


Gly Arg Cys Leu Thr Cys Glu Pro Gly Trp Asn Gly Thr Lys Cys Asp 
            260                 265                 270         


Gln Pro Cys Ala Thr Gly Phe Tyr Gly Glu Gly Cys Ser His Arg Cys 
        275                 280                 285             


Pro Pro Cys Arg Asp Gly His Ala Cys Asn His Val Thr Gly Lys Cys 
    290                 295                 300                 


Thr Arg Cys Asn Ala Gly Trp Ile Gly Asp Arg Cys Glu Thr Lys Cys 
305                 310                 315                 320 


Ser Asn Gly Thr Tyr Gly Glu Asp Cys Ala Phe Val Cys Ala Asp Cys 
                325                 330                 335     


Gly Ser Gly His Cys Asp Phe Gln Ser Gly Arg Cys Leu Cys Ser Pro 
            340                 345                 350         


Gly Val His Gly Pro His Cys Asn Val Thr Cys Pro Pro Gly Leu His 
        355                 360                 365             


Gly Ala Asp Cys Ala Gln Ala Cys Ser Cys His Glu Asp Thr Cys Asp 
    370                 375                 380                 


Pro Val Thr Gly Ala Cys His Leu Glu Thr Asn Gln Arg Lys 
385                 390                 395             


<210>  1157
<211>  142
<212>  PRT
<213>  Homo Sapiens

<400>  1157

Gly Gly Cys Val Glu Val Asp Ser Glu Thr Glu Ala Val Tyr Gly Met 
1               5                   10                  15      


Thr Phe Lys Ile Leu Cys Ile Ser Cys Lys Arg Arg Ser Glu Thr Asn 
            20                  25                  30          


Ala Glu Thr Phe Thr Glu Trp Thr Phe Arg Gln Lys Gly Thr Glu Glu 
        35                  40                  45              


Phe Val Lys Ile Leu Arg Tyr Glu Asn Glu Val Leu Gln Leu Glu Glu 
    50                  55                  60                  


Asp Glu Arg Phe Glu Gly Arg Val Val Trp Asn Gly Ser Arg Gly Thr 
65                  70                  75                  80  


Lys Asp Leu Gln Asp Leu Ser Ile Phe Ile Thr Asn Val Thr Tyr Asn 
                85                  90                  95      


His Ser Gly Asp Tyr Glu Cys His Val Tyr Arg Leu Leu Phe Phe Glu 
            100                 105                 110         


Asn Tyr Glu His Asn Thr Ser Val Val Lys Lys Ile His Ile Glu Val 
        115                 120                 125             


Val Asp Lys Ala Asn Arg Asp Met Ala Ser Ile Val Ser Glu 
    130                 135                 140         


<210>  1158
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  1158

Met Glu Val Thr Val Pro Ala Thr Leu Asn Val Leu Asn Gly Ser Asp 
1               5                   10                  15      


Ala Arg Leu Pro Cys Thr Phe Asn Ser Cys Tyr Thr Val Asn His Lys 
            20                  25                  30          


Gln Phe Ser Leu Asn Trp Thr Tyr Gln Glu Cys Asn Asn Cys Ser Glu 
        35                  40                  45              


Glu Met Phe Leu Gln Phe Arg Met Lys Ile Ile Asn Leu Lys Leu Glu 
    50                  55                  60                  


Arg Phe Gln Asp Arg Val Glu Phe Ser Gly Asn Pro Ser Lys Tyr Asp 
65                  70                  75                  80  


Val Ser Val Met Leu Arg Asn Val Gln Pro Glu Asp Glu Gly Ile Tyr 
                85                  90                  95      


Asn Cys Tyr Ile Met Asn Pro Pro Asp Arg His Arg Gly His Gly Lys 
            100                 105                 110         


Ile His Leu Gln Val Leu Met Glu Glu Pro Pro Glu Arg Asp Ser Thr 
        115                 120                 125             


Val Ala 
    130 


<210>  1159
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  1159

Phe Pro Val Cys Val Glu Val Pro Ser Glu Thr Glu Ala Val Gln Gly 
1               5                   10                  15      


Asn Pro Met Lys Leu Arg Cys Ile Ser Cys Met Lys Arg Glu Glu Val 
            20                  25                  30          


Glu Ala Thr Thr Val Val Glu Trp Phe Tyr Arg Pro Glu Gly Gly Lys 
        35                  40                  45              


Asp Phe Leu Ile Tyr Glu Tyr Arg Asn Gly His Gln Glu Val Glu Ser 
    50                  55                  60                  


Pro Phe Gln Gly Arg Leu Gln Trp Asn Gly Ser Lys Asp Leu Gln Asp 
65                  70                  75                  80  


Val Ser Ile Thr Val Leu Asn Val Thr Leu Asn Asp Ser Gly Leu Tyr 
                85                  90                  95      


Thr Cys Asn Val Ser Arg Glu Phe Glu Phe Glu Ala His Arg Pro Phe 
            100                 105                 110         


Val Lys Thr Thr Arg Leu Ile Pro Leu Arg Val Thr Glu Glu Ala Gly 
        115                 120                 125             


Glu Asp Phe Thr Ser Val Val Ser Glu 
    130                 135         


<210>  1160
<211>  132
<212>  PRT
<213>  Homo Sapiens

<400>  1160

Leu Glu Val Ser Val Gly Lys Ala Thr Asp Ile Tyr Ala Val Asn Gly 
1               5                   10                  15      


Thr Glu Ile Leu Leu Pro Cys Thr Phe Ser Ser Cys Phe Gly Phe Glu 
            20                  25                  30          


Asp Leu His Phe Arg Trp Thr Tyr Asn Ser Ser Asp Ala Phe Lys Ile 
        35                  40                  45              


Leu Ile Glu Gly Thr Val Lys Asn Glu Lys Ser Asp Pro Lys Val Thr 
    50                  55                  60                  


Leu Lys Asp Asp Asp Arg Ile Thr Leu Val Gly Ser Thr Lys Glu Lys 
65                  70                  75                  80  


Met Asn Asn Ile Ser Ile Val Leu Arg Asp Leu Glu Phe Ser Asp Thr 
                85                  90                  95      


Gly Lys Tyr Thr Cys His Val Lys Asn Pro Lys Glu Asn Asn Leu Gln 
            100                 105                 110         


His His Ala Thr Ile Phe Leu Gln Val Val Asp Arg Leu Glu Glu Val 
        115                 120                 125             


Asp Asn Thr Val 
    130         


<210>  1161
<211>  965
<212>  PRT
<213>  Homo Sapiens

<400>  1161

Gly Gly Ser Gly Leu Pro Gly Ser Val Asp Val Asp Glu Cys Ser Glu 
1               5                   10                  15      


Gly Thr Asp Asp Cys His Ile Asp Ala Ile Cys Gln Asn Thr Pro Lys 
            20                  25                  30          


Ser Tyr Lys Cys Leu Cys Lys Pro Gly Tyr Lys Gly Glu Gly Lys Gln 
        35                  40                  45              


Cys Glu Asp Ile Asp Glu Cys Glu Asn Asp Tyr Tyr Asn Gly Gly Cys 
    50                  55                  60                  


Val His Glu Cys Ile Asn Ile Pro Gly Asn Tyr Arg Cys Thr Cys Phe 
65                  70                  75                  80  


Asp Gly Phe Met Leu Ala His Asp Gly His Asn Cys Leu Asp Val Asp 
                85                  90                  95      


Glu Cys Gln Asp Asn Asn Gly Gly Cys Gln Gln Ile Cys Val Asn Ala 
            100                 105                 110         


Met Gly Ser Tyr Glu Cys Gln Cys His Ser Gly Phe Phe Leu Ser Asp 
        115                 120                 125             


Asn Gln His Thr Cys Ile His Arg Ser Asn Glu Gly Met Asn Cys Met 
    130                 135                 140                 


Asn Lys Asp His Gly Cys Ala His Ile Cys Arg Glu Thr Pro Lys Gly 
145                 150                 155                 160 


Gly Val Ala Cys Asp Cys Arg Pro Gly Phe Asp Leu Ala Gln Asn Gln 
                165                 170                 175     


Lys Asp Cys Thr Leu Thr Cys Asn Tyr Gly Asn Gly Gly Cys Gln His 
            180                 185                 190         


Ser Cys Glu Asp Thr Asp Thr Gly Pro Thr Cys Gly Cys His Gln Lys 
        195                 200                 205             


Tyr Ala Leu His Ser Asp Gly Arg Thr Cys Ile Glu Thr Cys Ala Val 
    210                 215                 220                 


Asn Asn Gly Gly Cys Asp Arg Thr Cys Lys Asp Thr Ala Thr Gly Val 
225                 230                 235                 240 


Arg Cys Ser Cys Pro Val Gly Phe Thr Leu Gln Pro Asp Gly Lys Thr 
                245                 250                 255     


Cys Lys Asp Ile Asn Glu Cys Leu Val Asn Asn Gly Gly Cys Asp His 
            260                 265                 270         


Phe Cys Arg Asn Thr Val Gly Ser Phe Glu Cys Gly Cys Arg Lys Gly 
        275                 280                 285             


Tyr Lys Leu Leu Thr Asp Glu Arg Thr Cys Gln Asp Ile Asp Glu Cys 
    290                 295                 300                 


Ser Phe Glu Arg Thr Cys Asp His Ile Cys Ile Asn Ser Pro Gly Ser 
305                 310                 315                 320 


Phe Gln Cys Leu Cys His Arg Gly Tyr Ile Leu Tyr Gly Thr Thr His 
                325                 330                 335     


Cys Gly Asp Val Asp Glu Cys Ser Met Ser Asn Gly Ser Cys Asp Gln 
            340                 345                 350         


Gly Cys Val Asn Thr Lys Gly Ser Tyr Glu Cys Val Cys Pro Pro Gly 
        355                 360                 365             


Arg Arg Leu His Trp Asn Gly Lys Asp Cys Val Glu Thr Gly Lys Cys 
    370                 375                 380                 


Leu Ser Arg Ala Lys Thr Ser Pro Arg Ala Gln Leu Ser Cys Ser Lys 
385                 390                 395                 400 


Ala Gly Gly Val Glu Ser Cys Phe Leu Ser Cys Pro Ala His Thr Leu 
                405                 410                 415     


Phe Val Pro Asp Ser Glu Asn Ser Tyr Val Leu Ser Cys Gly Val Pro 
            420                 425                 430         


Gly Pro Gln Gly Lys Ala Leu Gln Lys Arg Asn Gly Thr Ser Ser Gly 
        435                 440                 445             


Leu Gly Pro Ser Cys Ser Asp Ala Pro Thr Thr Pro Ile Lys Gln Lys 
    450                 455                 460                 


Ala Arg Phe Lys Ile Arg Asp Ala Lys Cys His Leu Arg Pro His Ser 
465                 470                 475                 480 


Gln Ala Arg Ala Lys Glu Thr Ala Arg Gln Pro Leu Leu Asp His Cys 
                485                 490                 495     


His Val Thr Phe Val Thr Leu Lys Cys Asp Ser Ser Lys Lys Arg Arg 
            500                 505                 510         


Arg Gly Arg Lys Ser Pro Ser Lys Glu Val Ser His Ile Thr Ala Glu 
        515                 520                 525             


Phe Glu Ile Glu Thr Lys Met Glu Glu Ala Ser Asp Thr Cys Glu Ala 
    530                 535                 540                 


Asp Cys Leu Arg Lys Arg Ala Glu Gln Ser Leu Gln Ala Ala Ile Lys 
545                 550                 555                 560 


Thr Leu Arg Lys Ser Ile Gly Arg Gln Gln Phe Tyr Val Gln Val Ser 
                565                 570                 575     


Gly Thr Glu Tyr Glu Val Ala Gln Arg Pro Ala Lys Ala Leu Glu Gly 
            580                 585                 590         


Gln Gly Ala Cys Gly Ala Gly Gln Val Leu Gln Asp Ser Lys Cys Val 
        595                 600                 605             


Ala Cys Gly Pro Gly Thr His Phe Gly Gly Glu Leu Gly Gln Cys Val 
    610                 615                 620                 


Ser Cys Met Pro Gly Thr Tyr Gln Asp Met Glu Gly Gln Leu Ser Cys 
625                 630                 635                 640 


Thr Pro Cys Pro Ser Ser Asp Gly Leu Gly Leu Pro Gly Ala Arg Asn 
                645                 650                 655     


Val Ser Glu Cys Gly Gly Gln Cys Ser Pro Gly Phe Phe Ser Ala Asp 
            660                 665                 670         


Gly Phe Lys Pro Cys Gln Ala Cys Pro Val Gly Thr Tyr Gln Pro Glu 
        675                 680                 685             


Pro Gly Arg Thr Gly Cys Phe Pro Cys Gly Gly Gly Leu Leu Thr Lys 
    690                 695                 700                 


His Glu Gly Thr Thr Ser Phe Gln Asp Cys Glu Ala Lys Val His Cys 
705                 710                 715                 720 


Ser Pro Gly His His Tyr Asn Thr Thr Thr His Arg Cys Ile Arg Cys 
                725                 730                 735     


Pro Val Gly Thr Tyr Gln Pro Glu Phe Gly Gln Asn His Cys Ile Thr 
            740                 745                 750         


Cys Pro Gly Asn Thr Ser Thr Asp Phe Asp Gly Ser Thr Asn Val Thr 
        755                 760                 765             


His Cys Lys Asn Gln His Cys Gly Gly Glu Leu Gly Asp Tyr Thr Gly 
    770                 775                 780                 


Tyr Ile Glu Ser Pro Asn Tyr Pro Gly Asp Tyr Pro Ala Asn Ala Glu 
785                 790                 795                 800 


Cys Val Trp His Ile Ala Pro Pro Pro Lys Arg Arg Ile Leu Ile Val 
                805                 810                 815     


Val Pro Glu Ile Phe Leu Pro Ile Glu Asp Glu Cys Gly Asp Val Leu 
            820                 825                 830         


Val Met Arg Lys Ser Ala Ser Pro Thr Ser Ile Thr Thr Tyr Glu Thr 
        835                 840                 845             


Cys Gln Thr Tyr Glu Arg Pro Ile Ala Phe Thr Ser Arg Ser Arg Lys 
    850                 855                 860                 


Leu Trp Ile Gln Phe Lys Ser Asn Glu Gly Asn Ser Gly Lys Gly Phe 
865                 870                 875                 880 


Gln Val Pro Tyr Val Thr Tyr Asp Glu Asp Tyr Gln Gln Leu Ile Glu 
                885                 890                 895     


Asp Ile Val Arg Asp Gly Arg Leu Tyr Ala Ser Glu Asn His Gln Glu 
            900                 905                 910         


Ile Leu Lys Asp Lys Lys Leu Ile Lys Ala Leu Phe Asp Val Leu Ala 
        915                 920                 925             


His Pro Gln Asn Tyr Phe Lys Tyr Thr Ala Gln Glu Ser Lys Glu Met 
    930                 935                 940                 


Phe Pro Arg Ser Phe Ile Lys Leu Leu Arg Ser Lys Val Ser Arg Phe 
945                 950                 955                 960 


Leu Arg Pro Tyr Lys 
                965 


<210>  1162
<211>  776
<212>  PRT
<213>  Homo Sapiens

<400>  1162

Val Pro Pro Gly Arg Gly Arg Ala Ala Gly Pro Gln Glu Asp Val Asp 
1               5                   10                  15      


Glu Cys Ala Gln Gly Leu Asp Asp Cys His Ala Asp Ala Leu Cys Gln 
            20                  25                  30          


Asn Thr Pro Thr Ser Tyr Lys Cys Ser Cys Lys Pro Gly Tyr Gln Gly 
        35                  40                  45              


Glu Gly Arg Gln Cys Glu Asp Ile Asp Glu Cys Gly Asn Glu Leu Asn 
    50                  55                  60                  


Gly Gly Cys Val His Asp Cys Leu Asn Ile Pro Gly Asn Tyr Arg Cys 
65                  70                  75                  80  


Thr Cys Phe Asp Gly Phe Met Leu Ala His Asp Gly His Asn Cys Leu 
                85                  90                  95      


Asp Val Asp Glu Cys Leu Glu Asn Asn Gly Gly Cys Gln His Thr Cys 
            100                 105                 110         


Val Asn Val Met Gly Ser Tyr Glu Cys Cys Cys Lys Glu Gly Phe Phe 
        115                 120                 125             


Leu Ser Asp Asn Gln His Thr Cys Ile His Arg Ser Glu Glu Gly Leu 
    130                 135                 140                 


Ser Cys Met Asn Lys Asp His Gly Cys Ser His Ile Cys Lys Glu Ala 
145                 150                 155                 160 


Pro Arg Gly Ser Val Ala Cys Glu Cys Arg Pro Gly Phe Glu Leu Ala 
                165                 170                 175     


Lys Asn Gln Arg Asp Cys Ile Leu Thr Cys Asn His Gly Asn Gly Gly 
            180                 185                 190         


Cys Gln His Ser Cys Asp Asp Thr Ala Asp Gly Pro Glu Cys Ser Cys 
        195                 200                 205             


His Pro Gln Tyr Lys Met His Thr Asp Gly Arg Ser Cys Leu Glu Arg 
    210                 215                 220                 


Glu Asp Thr Val Leu Glu Val Thr Glu Ser Asn Thr Thr Ser Val Val 
225                 230                 235                 240 


Asp Gly Asp Lys Arg Val Lys Arg Arg Leu Leu Met Glu Thr Cys Ala 
                245                 250                 255     


Val Asn Asn Gly Gly Cys Asp Arg Thr Cys Lys Asp Thr Ser Thr Gly 
            260                 265                 270         


Val His Cys Ser Cys Pro Val Gly Phe Thr Leu Gln Leu Asp Gly Lys 
        275                 280                 285             


Thr Cys Lys Asp Ile Asp Glu Cys Gln Thr Arg Asn Gly Gly Cys Asp 
    290                 295                 300                 


His Phe Cys Lys Asn Ile Val Gly Ser Phe Asp Cys Gly Cys Lys Lys 
305                 310                 315                 320 


Gly Phe Lys Leu Leu Thr Asp Glu Lys Ser Cys Gln Asp Val Asp Glu 
                325                 330                 335     


Cys Ser Leu Asp Arg Thr Cys Asp His Ser Cys Ile Asn His Pro Gly 
            340                 345                 350         


Thr Phe Ala Cys Ala Cys Asn Arg Gly Tyr Thr Leu Tyr Gly Phe Thr 
        355                 360                 365             


His Cys Gly Asp Thr Asn Glu Cys Ser Ile Asn Asn Gly Gly Cys Gln 
    370                 375                 380                 


Gln Val Cys Val Asn Thr Val Gly Ser Tyr Glu Cys Gln Cys His Pro 
385                 390                 395                 400 


Gly Tyr Lys Leu His Trp Asn Lys Lys Asp Cys Val Ala Ser Cys Asp 
                405                 410                 415     


Leu Ser Cys Ile Val Lys Arg Thr Glu Lys Arg Leu Arg Lys Ala Ile 
            420                 425                 430         


Arg Thr Leu Arg Lys Ala Val His Arg Glu Gln Phe His Leu Gln Leu 
        435                 440                 445             


Ser Gly Met Asn Leu Asp Val Ala Lys Lys Pro Pro Arg Thr Ser Glu 
    450                 455                 460                 


Arg Gln Ala Glu Ser Cys Gly Val Gly Gln Gly His Ala Glu Asn Gln 
465                 470                 475                 480 


Cys Val Ser Cys Arg Ala Gly Thr Tyr Tyr Asp Gly Ala Arg Glu Arg 
                485                 490                 495     


Cys Ile Leu Cys Pro Asn Gly Thr Phe Gln Asn Glu Glu Gly Gln Met 
            500                 505                 510         


Thr Cys Glu Pro Cys Pro Arg Pro Gly Asn Ser Gly Ala Leu Lys Thr 
        515                 520                 525             


Pro Glu Ala Trp Asn Met Ser Glu Cys Gly Gly Leu Cys Gln Pro Gly 
    530                 535                 540                 


Glu Tyr Ser Ala Asp Gly Phe Ala Pro Cys Gln Leu Cys Ala Leu Gly 
545                 550                 555                 560 


Thr Phe Gln Pro Glu Ala Gly Arg Thr Ser Cys Phe Pro Cys Gly Gly 
                565                 570                 575     


Gly Leu Ala Thr Lys His Gln Gly Ala Thr Ser Phe Gln Asp Cys Glu 
            580                 585                 590         


Thr Arg Val Gln Cys Ser Pro Gly His Phe Tyr Asn Thr Thr Thr His 
        595                 600                 605             


Arg Cys Ile Arg Cys Pro Val Gly Thr Tyr Gln Pro Glu Phe Gly Lys 
    610                 615                 620                 


Asn Asn Cys Val Ser Cys Pro Gly Asn Thr Thr Thr Asp Phe Asp Gly 
625                 630                 635                 640 


Ser Thr Asn Ile Thr Gln Cys Lys Thr Ser Ser Asn Ser Val Thr Thr 
                645                 650                 655     


Tyr Glu Thr Cys Gln Thr Tyr Glu Arg Pro Ile Ala Phe Thr Ser Arg 
            660                 665                 670         


Ser Lys Lys Leu Trp Ile Gln Phe Lys Ser Asn Glu Gly Asn Ser Ala 
        675                 680                 685             


Arg Gly Phe Gln Val Pro Tyr Val Thr Tyr Asp Glu Asp Tyr Gln Glu 
    690                 695                 700                 


Leu Ile Glu Asp Ile Val Arg Asp Gly Arg Leu Tyr Ala Ser Glu Asn 
705                 710                 715                 720 


His Gln Glu Ile Leu Lys Asp Lys Lys Leu Ile Lys Ala Leu Phe Asp 
                725                 730                 735     


Val Leu Ala His Pro Gln Asn Tyr Phe Lys Tyr Thr Ala Gln Glu Ser 
            740                 745                 750         


Arg Glu Met Phe Pro Arg Ser Phe Ile Arg Leu Leu Arg Ser Lys Val 
        755                 760                 765             


Ser Arg Phe Leu Arg Pro Tyr Lys 
    770                 775     


<210>  1163
<211>  972
<212>  PRT
<213>  Homo Sapiens

<400>  1163

Ala Gln Tyr Ser Lys Ala Ala Gln Asp Val Asp Glu Cys Val Glu Gly 
1               5                   10                  15      


Thr Asp Asn Cys His Ile Asp Ala Ile Cys Gln Asn Thr Pro Arg Ser 
            20                  25                  30          


Tyr Lys Cys Ile Cys Lys Ser Gly Tyr Thr Gly Asp Gly Lys His Cys 
        35                  40                  45              


Lys Asp Val Asp Glu Cys Glu Arg Glu Asp Asn Ala Gly Cys Val His 
    50                  55                  60                  


Asp Cys Val Asn Ile Pro Gly Asn Tyr Arg Cys Thr Cys Tyr Asp Gly 
65                  70                  75                  80  


Phe His Leu Ala His Asp Gly His Asn Cys Leu Asp Val Asp Glu Cys 
                85                  90                  95      


Ala Glu Gly Asn Gly Gly Cys Gln Gln Ser Cys Val Asn Met Met Gly 
            100                 105                 110         


Ser Tyr Glu Cys His Cys Arg Glu Gly Phe Phe Leu Ser Asp Asn Gln 
        115                 120                 125             


His Thr Cys Ile Gln Arg Pro Glu Gly Met Asn Cys Met Asn Lys Asn 
    130                 135                 140                 


His Gly Cys Ala His Ile Cys Arg Glu Thr Pro Lys Gly Gly Ile Ala 
145                 150                 155                 160 


Cys Glu Cys Arg Pro Gly Phe Glu Leu Thr Lys Asn Gln Arg Asp Cys 
                165                 170                 175     


Lys Leu Thr Cys Asn Tyr Gly Asn Gly Gly Cys Gln His Thr Cys Asp 
            180                 185                 190         


Asp Thr Glu Gln Gly Pro Arg Cys Gly Cys His Ile Lys Phe Val Leu 
        195                 200                 205             


His Thr Asp Gly Lys Thr Cys Ile Glu Thr Cys Ala Val Asn Asn Gly 
    210                 215                 220                 


Gly Cys Asp Ser Lys Cys His Asp Ala Ala Ile Gly Val His Cys Thr 
225                 230                 235                 240 


Cys Pro Val Gly Phe Met Leu Gln Pro Asp Arg Lys Thr Cys Lys Asp 
                245                 250                 255     


Ile Asp Glu Cys Arg Leu Asn Asn Gly Gly Cys Asp His Ile Cys Arg 
            260                 265                 270         


Asn Thr Val Gly Ser Phe Glu Cys Ser Cys Lys Lys Gly Tyr Lys Leu 
        275                 280                 285             


Leu Ile Asn Glu Arg Asn Cys Gln Asp Ile Asp Glu Cys Ser Phe Asp 
    290                 295                 300                 


Arg Thr Cys Asp His Ile Cys Val Asn Thr Pro Gly Ser Phe Gln Cys 
305                 310                 315                 320 


Leu Cys His Arg Gly Tyr Leu Leu Tyr Gly Ile Thr His Cys Gly Asp 
                325                 330                 335     


Val Asp Glu Cys Ser Ile Asn Arg Gly Gly Cys Arg Phe Gly Cys Ile 
            340                 345                 350         


Asn Thr Pro Gly Ser Tyr Gln Cys Thr Cys Pro Ala Gly Gln Gly Arg 
        355                 360                 365             


Leu His Trp Asn Gly Lys Asp Cys Thr Glu Pro Leu Lys Cys Gln Gly 
    370                 375                 380                 


Ser Pro Gly Ala Ser Lys Ala Met Leu Ser Cys Asn Arg Ser Gly Lys 
385                 390                 395                 400 


Lys Asp Thr Cys Ala Leu Thr Cys Pro Ser Arg Ala Arg Phe Leu Pro 
                405                 410                 415     


Glu Ser Glu Asn Gly Phe Thr Val Ser Cys Gly Thr Pro Ser Pro Arg 
            420                 425                 430         


Ala Ala Pro Ala Arg Ala Gly His Asn Gly Asn Ser Thr Asn Ser Asn 
        435                 440                 445             


His Cys His Glu Ala Ala Val Leu Ser Ile Lys Gln Arg Ala Ser Phe 
    450                 455                 460                 


Lys Ile Lys Asp Ala Lys Cys Arg Leu His Leu Arg Asn Lys Gly Lys 
465                 470                 475                 480 


Thr Glu Glu Ala Gly Arg Ile Thr Gly Pro Gly Gly Ala Pro Cys Ser 
                485                 490                 495     


Glu Cys Gln Val Thr Phe Ile His Leu Lys Cys Asp Ser Ser Arg Lys 
            500                 505                 510         


Gly Lys Gly Arg Arg Ala Arg Thr Pro Pro Gly Lys Glu Val Thr Arg 
        515                 520                 525             


Leu Thr Leu Glu Leu Glu Ala Glu Val Arg Ala Glu Glu Thr Thr Ala 
    530                 535                 540                 


Ser Cys Gly Leu Pro Cys Leu Arg Gln Arg Met Glu Arg Arg Leu Lys 
545                 550                 555                 560 


Gly Ser Leu Lys Met Leu Arg Lys Ser Ile Asn Gln Asp Arg Phe Leu 
                565                 570                 575     


Leu Arg Leu Ala Gly Leu Asp Tyr Glu Leu Ala His Lys Pro Gly Leu 
            580                 585                 590         


Val Ala Gly Glu Arg Ala Glu Pro Met Glu Ser Cys Arg Pro Gly Gln 
        595                 600                 605             


His Arg Ala Gly Thr Lys Cys Val Ser Cys Pro Gln Gly Thr Tyr Tyr 
    610                 615                 620                 


His Gly Gln Thr Glu Gln Cys Val Pro Cys Pro Ala Gly Thr Phe Gln 
625                 630                 635                 640 


Glu Arg Glu Gly Gln Leu Ser Cys Asp Leu Cys Pro Gly Ser Asp Ala 
                645                 650                 655     


His Gly Pro Leu Gly Ala Thr Asn Val Thr Thr Cys Ala Gly Gln Cys 
            660                 665                 670         


Pro Pro Gly Gln His Ser Val Asp Gly Phe Lys Pro Cys Gln Pro Cys 
        675                 680                 685             


Pro Arg Gly Thr Tyr Gln Pro Glu Ala Gly Arg Thr Leu Cys Phe Pro 
    690                 695                 700                 


Cys Gly Gly Gly Leu Thr Thr Lys His Glu Gly Ala Ile Ser Phe Gln 
705                 710                 715                 720 


Asp Cys Asp Thr Lys Val Gln Cys Ser Pro Gly His Tyr Tyr Asn Thr 
                725                 730                 735     


Ser Ile His Arg Cys Ile Arg Cys Ala Met Gly Ser Tyr Gln Pro Asp 
            740                 745                 750         


Phe Arg Gln Asn Phe Cys Ser Arg Cys Pro Gly Asn Thr Ser Thr Asp 
        755                 760                 765             


Phe Asp Gly Ser Thr Ser Val Ala Gln Cys Lys Asn Arg Gln Cys Gly 
    770                 775                 780                 


Gly Glu Leu Gly Glu Phe Thr Gly Tyr Ile Glu Ser Pro Asn Tyr Pro 
785                 790                 795                 800 


Gly Asn Tyr Pro Ala Gly Val Glu Cys Ile Trp Asn Ile Asn Pro Pro 
                805                 810                 815     


Pro Lys Arg Lys Ile Leu Ile Val Val Pro Glu Ile Phe Leu Pro Ser 
            820                 825                 830         


Glu Asp Glu Cys Gly Asp Val Leu Val Met Arg Lys Asn Ser Ser Pro 
        835                 840                 845             


Ser Ser Ile Thr Thr Tyr Glu Thr Cys Gln Thr Tyr Glu Arg Pro Ile 
    850                 855                 860                 


Ala Phe Thr Ala Arg Ser Arg Lys Leu Trp Ile Asn Phe Lys Thr Ser 
865                 870                 875                 880 


Glu Ala Asn Ser Ala Arg Gly Phe Gln Ile Pro Tyr Val Thr Tyr Asp 
                885                 890                 895     


Glu Asp Tyr Glu Gln Leu Val Glu Asp Ile Val Arg Asp Gly Arg Leu 
            900                 905                 910         


Tyr Ala Ser Glu Asn His Gln Glu Ile Leu Lys Asp Lys Lys Leu Ile 
        915                 920                 925             


Lys Ala Phe Phe Glu Val Leu Ala His Pro Gln Asn Tyr Phe Lys Tyr 
    930                 935                 940                 


Thr Glu Lys His Lys Glu Met Leu Pro Lys Ser Phe Ile Lys Leu Leu 
945                 950                 955                 960 


Arg Ser Lys Val Ser Ser Phe Leu Arg Pro Tyr Lys 
                965                 970         


<210>  1164
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  1164

Gln Ile Val Ala Thr Asn Leu Pro Pro Glu Asp Gln Asp Gly Ser Gly 
1               5                   10                  15      


Asp Asp Ser Asp Asn Phe Ser Gly Ser Gly Ala Gly Ala Leu Gln Asp 
            20                  25                  30          


Ile Thr Leu Ser Gln Gln Thr Pro Ser Thr Trp Lys Asp Thr Gln Leu 
        35                  40                  45              


Leu Thr Ala Ile Pro Thr Ser Pro Glu Pro Thr Gly Leu Glu Ala Thr 
    50                  55                  60                  


Ala Ala Ser Thr Ser Thr Leu Pro Ala Gly Glu Gly Pro Lys Glu Gly 
65                  70                  75                  80  


Glu Ala Val Val Leu Pro Glu Val Glu Pro Gly Leu Thr Ala Arg Glu 
                85                  90                  95      


Gln Glu Ala Thr Pro Arg Pro Arg Glu Thr Thr Gln Leu Pro Thr Thr 
            100                 105                 110         


His Gln Ala Ser Thr Thr Thr Ala Thr Thr Ala Gln Glu Pro Ala Thr 
        115                 120                 125             


Ser His Pro His Arg Asp Met Gln Pro Gly His His Glu Thr Ser Thr 
    130                 135                 140                 


Pro Ala Gly Pro Ser Gln Ala Asp Leu His Thr Pro His Thr Glu Asp 
145                 150                 155                 160 


Gly Gly Pro Ser Ala Thr Glu Arg Ala Ala Glu Asp Gly Ala Ser Ser 
                165                 170                 175     


Gln Leu Pro Ala Ala Glu Gly Ser Gly Glu Gln Asp Phe Thr Phe Glu 
            180                 185                 190         


Thr Ser Gly Glu Asn Thr Ala Val Val Ala Val Glu Pro Asp Arg Arg 
        195                 200                 205             


Asn Gln Ser Pro Val Asp Gln Gly Ala Thr Gly Ala 
    210                 215                 220 


<210>  1165
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  1165

Glu Ser Arg Ala Glu Leu Thr Ser Asp Lys Asp Met Tyr Leu Asp Asn 
1               5                   10                  15      


Ser Ser Ile Glu Glu Ala Ser Gly Val Tyr Pro Ile Asp Asp Asp Asp 
            20                  25                  30          


Tyr Ala Ser Ala Ser Gly Ser Gly Ala Asp Glu Asp Val Glu Ser Pro 
        35                  40                  45              


Glu Leu Thr Thr Thr Arg Pro Leu Pro Lys Ile Leu Leu Thr Ser Ala 
    50                  55                  60                  


Ala Pro Lys Val Glu Thr Thr Thr Leu Asn Ile Gln Asn Lys Ile Pro 
65                  70                  75                  80  


Ala Gln Thr Lys Ser Pro Glu Glu Thr Asp Lys Glu Lys Val His Leu 
                85                  90                  95      


Ser Asp Ser Glu Arg Lys Met Asp Pro Ala Glu Glu Asp Thr Asn Val 
            100                 105                 110         


Tyr Thr Glu Lys His Ser Asp Ser Leu Phe Lys Arg Thr Glu 
        115                 120                 125     


<210>  1166
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  1166

Glu Ser Ile Arg Glu Thr Glu Val Ile Asp Pro Gln Asp Leu Leu Glu 
1               5                   10                  15      


Gly Arg Tyr Phe Ser Gly Ala Leu Pro Asp Asp Glu Asp Val Val Gly 
            20                  25                  30          


Pro Gly Gln Glu Ser Asp Asp Phe Glu Leu Ser Gly Ser Gly Asp Leu 
        35                  40                  45              


Asp Asp Leu Glu Asp Ser Met Ile Gly Pro Glu Val Val His Pro Leu 
    50                  55                  60                  


Val Pro Leu Asp Asn His Ile Pro Glu Arg Ala Gly Ser Gly Ser Gln 
65                  70                  75                  80  


Val Pro Thr Glu Pro Lys Lys Leu Glu Glu Asn Glu Val Ile Pro Lys 
                85                  90                  95      


Arg Ile Ser Pro Val Glu Glu Ser Glu Asp Val Ser Asn Lys Val Ser 
            100                 105                 110         


Met Ser Ser Thr Val Gln Gly Ser Asn Ile Phe Glu Arg Thr Glu 
        115                 120                 125         


<210>  1167
<211>  1531
<212>  PRT
<213>  Homo Sapiens

<400>  1167

Pro Asn Ile Thr Arg Gly Pro Leu Asp Ser Thr Val Ile Asp Gly Met 
1               5                   10                  15      


Ser Val Val Leu Ala Cys Glu Thr Ser Gly Ala Pro Arg Pro Ala Ile 
            20                  25                  30          


Thr Trp Gln Lys Gly Glu Arg Ile Leu Ala Ser Gly Ser Val Gln Leu 
        35                  40                  45              


Pro Arg Phe Thr Pro Leu Glu Ser Gly Ser Leu Leu Ile Ser Pro Thr 
    50                  55                  60                  


His Ile Ser Asp Ala Gly Thr Tyr Thr Cys Leu Ala Thr Asn Ser Arg 
65                  70                  75                  80  


Gly Val Asp Glu Ala Ser Ala Asp Leu Val Val Trp Ala Arg Thr Arg 
                85                  90                  95      


Ile Thr Lys Pro Pro Gln Asp Gln Ser Val Ile Lys Gly Thr Gln Ala 
            100                 105                 110         


Ser Met Val Cys Gly Val Thr His Asp Pro Arg Val Thr Ile Arg Tyr 
        115                 120                 125             


Ile Trp Glu Lys Asp Gly Ala Thr Leu Gly Thr Glu Ser His Pro Arg 
    130                 135                 140                 


Ile Arg Leu Asp Arg Asn Gly Ser Leu His Ile Ser Gln Thr Trp Ser 
145                 150                 155                 160 


Gly Asp Ile Gly Thr Tyr Thr Cys Arg Val Ile Ser Ala Gly Gly Asn 
                165                 170                 175     


Asp Ser Arg Ser Ala His Leu Arg Val Arg Gln Leu Pro His Ala Pro 
            180                 185                 190         


Glu His Pro Val Ala Thr Leu Ser Thr Val Glu Arg Arg Ala Ile Asn 
        195                 200                 205             


Leu Thr Trp Thr Lys Pro Phe Asp Gly Asn Ser Pro Leu Ile Arg Tyr 
    210                 215                 220                 


Ile Leu Glu Met Ser Glu Asn Asn Ala Pro Trp Thr Val Leu Leu Ala 
225                 230                 235                 240 


Ser Val Asp Pro Lys Ala Thr Ser Val Thr Val Lys Gly Leu Val Pro 
                245                 250                 255     


Ala Arg Ser Tyr Gln Phe Arg Leu Cys Ala Val Asn Asp Val Gly Lys 
            260                 265                 270         


Gly Gln Phe Ser Lys Asp Thr Glu Arg Val Ser Leu Pro Glu Glu Pro 
        275                 280                 285             


Pro Thr Ala Pro Pro Gln Asn Val Ile Ala Ser Gly Arg Thr Asn Gln 
    290                 295                 300                 


Ser Ile Met Ile Gln Trp Gln Pro Pro Pro Glu Ser His Gln Asn Gly 
305                 310                 315                 320 


Ile Leu Lys Gly Tyr Ile Ile Arg Tyr Cys Leu Ala Gly Leu Pro Val 
                325                 330                 335     


Gly Tyr Gln Phe Lys Asn Ile Thr Asp Ala Asp Val Asn Asn Leu Leu 
            340                 345                 350         


Leu Glu Asp Leu Ile Ile Trp Thr Asn Tyr Glu Ile Glu Val Ala Ala 
        355                 360                 365             


Tyr Asn Ser Ala Gly Leu Gly Val Tyr Ser Ser Lys Val Thr Glu Trp 
    370                 375                 380                 


Thr Leu Gln Gly Val Pro Thr Val Pro Pro Gly Asn Val His Ala Glu 
385                 390                 395                 400 


Ala Thr Asn Ser Thr Thr Ile Arg Phe Thr Trp Asn Ala Pro Ser Pro 
                405                 410                 415     


Gln Phe Ile Asn Gly Ile Asn Gln Gly Tyr Lys Leu Ile Ala Trp Glu 
            420                 425                 430         


Pro Glu Gln Glu Glu Glu Val Thr Met Val Thr Ala Arg Pro Asn Phe 
        435                 440                 445             


Gln Asp Ser Ile His Val Gly Phe Val Ser Gly Leu Lys Lys Phe Thr 
    450                 455                 460                 


Glu Tyr Phe Thr Ser Val Leu Cys Phe Thr Thr Pro Gly Asp Gly Pro 
465                 470                 475                 480 


Arg Ser Thr Pro Gln Leu Val Arg Thr His Glu Asp Val Pro Gly Pro 
                485                 490                 495     


Val Gly His Leu Ser Phe Ser Glu Ile Leu Asp Thr Ser Leu Lys Val 
            500                 505                 510         


Ser Trp Gln Glu Pro Gly Glu Lys Asn Gly Ile Leu Thr Gly Tyr Arg 
        515                 520                 525             


Ile Ser Trp Glu Glu Tyr Asn Arg Thr Asn Thr Arg Val Thr His Tyr 
    530                 535                 540                 


Leu Pro Asn Val Thr Leu Glu Tyr Arg Val Thr Gly Leu Thr Ala Leu 
545                 550                 555                 560 


Thr Thr Tyr Thr Ile Glu Val Ala Ala Met Thr Ser Lys Gly Gln Gly 
                565                 570                 575     


Gln Val Ser Ala Ser Thr Ile Ser Ser Gly Val Pro Pro Glu Leu Pro 
            580                 585                 590         


Gly Pro Pro Thr Asn Leu Gly Ile Ser Asn Ile Gly Pro Arg Ser Val 
        595                 600                 605             


Thr Leu Gln Phe Arg Pro Gly Tyr Asp Gly Lys Thr Ser Ile Ser Arg 
    610                 615                 620                 


Trp Leu Val Glu Ala Gln Val Gly Val Val Gly Glu Gly Glu Glu Trp 
625                 630                 635                 640 


Leu Leu Ile His Gln Leu Ser Asn Glu Pro Asp Ala Arg Ser Met Glu 
                645                 650                 655     


Val Pro Asp Leu Asn Pro Phe Thr Cys Tyr Ser Phe Arg Met Arg Gln 
            660                 665                 670         


Val Asn Ile Val Gly Thr Ser Pro Pro Ser Gln Pro Ser Arg Lys Ile 
        675                 680                 685             


Gln Thr Leu Gln Ala Pro Pro Asp Met Ala Pro Ala Asn Val Ser Leu 
    690                 695                 700                 


Arg Thr Ala Ser Glu Thr Ser Leu Trp Leu Arg Trp Met Pro Leu Pro 
705                 710                 715                 720 


Glu Met Glu Tyr Asn Gly Asn Pro Glu Ser Val Gly Tyr Lys Ile Lys 
                725                 730                 735     


Tyr Ser Arg Ser Asp Gly His Gly Lys Thr Leu Ser His Val Val Gln 
            740                 745                 750         


Asp Arg Val Glu Arg Asp Tyr Thr Ile Glu Asp Leu Glu Glu Trp Thr 
        755                 760                 765             


Glu Tyr Arg Val Gln Val Gln Ala Phe Asn Ala Ile Gly Ser Gly Pro 
    770                 775                 780                 


Trp Ser Gln Thr Val Val Gly Arg Thr Arg Glu Ser Val Pro Ser Ser 
785                 790                 795                 800 


Gly Pro Thr Asn Val Ser Ala Leu Ala Thr Thr Ser Ser Ser Met Leu 
                805                 810                 815     


Val Arg Trp Ser Glu Val Pro Glu Ala Asp Arg Asn Gly Leu Val Leu 
            820                 825                 830         


Gly Tyr Lys Val Met Tyr Lys Glu Lys Asp Ser Asp Thr Gln Pro Arg 
        835                 840                 845             


Phe Trp Leu Val Glu Gly Asn Ser Ser Arg Ser Ala Gln Leu Thr Gly 
    850                 855                 860                 


Leu Gly Lys Tyr Val Leu Tyr Glu Val Gln Val Leu Ala Phe Thr Arg 
865                 870                 875                 880 


Ile Gly Asp Gly Ser Pro Ser His Pro Pro Ile Leu Glu Arg Thr Leu 
                885                 890                 895     


Asp Asp Val Pro Gly Pro Pro Met Gly Ile Leu Phe Pro Glu Val Arg 
            900                 905                 910         


Thr Thr Ser Val Arg Leu Ile Trp Gln Pro Pro Ala Ala Pro Asn Gly 
        915                 920                 925             


Ile Ile Leu Ala Tyr Gln Ile Thr His Arg Leu Asn Thr Thr Thr Ala 
    930                 935                 940                 


Asn Thr Ala Thr Val Glu Val Leu Ala Pro Ser Ala Arg Gln Tyr Thr 
945                 950                 955                 960 


Ala Thr Gly Leu Lys Pro Glu Ser Val Tyr Leu Phe Arg Ile Thr Ala 
                965                 970                 975     


Gln Thr Arg Lys Gly Trp Gly Glu Ala Ala Glu Ala Leu Val Val Thr 
            980                 985                 990         


Thr Glu Lys Arg Asp Arg Pro Gln  Pro Pro Ser Arg Pro  Met Val Gln 
        995                 1000                 1005             


Gln Glu  Asp Val Arg Ala Arg  Ser Val Leu Leu Ser  Trp Glu Pro 
    1010                 1015                 1020             


Gly Ser  Asp Gly Leu Ser Pro  Val Arg Tyr Tyr Thr  Ile Gln Thr 
    1025                 1030                 1035             


Arg Glu  Leu Pro Ser Gly Arg  Trp Ala Leu His Ser  Ala Ser Val 
    1040                 1045                 1050             


Ser His  Asn Ala Ser Ser Phe  Ile Val Asp Arg Leu  Lys Pro Phe 
    1055                 1060                 1065             


Thr Ser  Tyr Lys Phe Arg Val  Lys Ala Thr Asn Asp  Ile Gly Asp 
    1070                 1075                 1080             


Ser Glu  Phe Ser Glu Glu Ser  Glu Ser Leu Thr Thr  Leu Gln Ala 
    1085                 1090                 1095             


Ala Pro  Asp Glu Ala Pro Thr  Ile Leu Ser Val Thr  Pro His Thr 
    1100                 1105                 1110             


Thr Thr  Ser Val Leu Ile Arg  Trp Gln Pro Pro Ala  Glu Asp Lys 
    1115                 1120                 1125             


Ile Asn  Gly Ile Leu Leu Gly  Phe Arg Ile Arg Tyr  Arg Glu Leu 
    1130                 1135                 1140             


Leu Tyr  Glu Gly Leu Arg Gly  Phe Met Leu Arg Gly  Ile Asn Asn 
    1145                 1150                 1155             


Pro Gly  Ala Thr Trp Ala Glu  Leu Thr Ser Met Tyr  Ser Met Arg 
    1160                 1165                 1170             


Asn Leu  Ser Arg Pro Ser Leu  Thr Gln Tyr Glu Leu  Asp Asn Leu 
    1175                 1180                 1185             


Asn Lys  His Arg Arg Tyr Glu  Ile Arg Met Ser Val  Tyr Asn Ala 
    1190                 1195                 1200             


Val Gly  Glu Gly Pro Ser Ser  Pro Pro Gln Glu Val  Phe Val Gly 
    1205                 1210                 1215             


Glu Ala  Val Pro Thr Ala Ala  Pro Arg Asn Val Val  Val His Gly 
    1220                 1225                 1230             


Ala Thr  Ala Thr Gln Leu Asp  Val Thr Trp Glu Pro  Pro Pro Leu 
    1235                 1240                 1245             


Asp Ser  Gln Asn Gly Asp Ile  Gln Gly Tyr Lys Ile  Tyr Phe Trp 
    1250                 1255                 1260             


Glu Ala  Gln Arg Gly Asn Leu  Thr Glu Arg Val Lys  Thr Leu Phe 
    1265                 1270                 1275             


Leu Ala  Glu Asn Ser Val Lys  Leu Lys Asn Leu Thr  Gly Tyr Thr 
    1280                 1285                 1290             


Ala Tyr  Met Val Ser Val Ala  Ala Phe Asn Ala Ala  Gly Asp Gly 
    1295                 1300                 1305             


Pro Arg  Ser Thr Pro Thr Gln  Gly Gln Thr Gln Gln  Ala Ala Pro 
    1310                 1315                 1320             


Ser Ala  Pro Ser Ser Val Lys  Phe Ser Glu Leu Thr  Thr Thr Ser 
    1325                 1330                 1335             


Val Asn  Val Ser Trp Glu Ala  Pro Gln Phe Pro Asn  Gly Ile Leu 
    1340                 1345                 1350             


Glu Gly  Tyr Arg Leu Val Tyr  Glu Pro Cys Ser Pro  Val Asp Gly 
    1355                 1360                 1365             


Val Ser  Lys Ile Val Thr Val  Asp Val Lys Gly Asn  Ser Pro Leu 
    1370                 1375                 1380             


Trp Leu  Lys Val Lys Asp Leu  Ala Glu Gly Val Thr  Tyr Arg Phe 
    1385                 1390                 1395             


Arg Ile  Arg Ala Lys Thr Phe  Thr Tyr Gly Pro Glu  Ile Glu Ala 
    1400                 1405                 1410             


Asn Val  Thr Thr Gly Pro Gly  Glu Gly Ala Pro Gly  Pro Pro Gly 
    1415                 1420                 1425             


Val Pro  Ile Ile Val Arg Tyr  Ser Ser Ala Ile Ala  Ile His Trp 
    1430                 1435                 1440             


Ser Ser  Gly Asp Pro Gly Lys  Gly Pro Ile Thr Arg  Tyr Val Ile 
    1445                 1450                 1455             


Glu Ala  Arg Pro Ser Asp Glu  Gly Leu Trp Asp Ile  Leu Ile Lys 
    1460                 1465                 1470             


Asp Ile  Pro Lys Glu Val Ser  Ser Tyr Thr Phe Ser  Met Asp Ile 
    1475                 1480                 1485             


Leu Lys  Pro Gly Val Ser Tyr  Asp Phe Arg Val Ile  Ala Val Asn 
    1490                 1495                 1500             


Asp Tyr  Gly Phe Gly Thr Pro  Ser Ser Pro Ser Gln  Ser Val Pro 
    1505                 1510                 1515             


Ala Gln  Lys Ala Asn Pro Phe  Tyr Glu Glu Trp Trp  Phe 
    1520                 1525                 1530     


<210>  1168
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  1168

Gln Asn Glu Gly Trp Asp Ser Pro Ile Cys Thr Glu Gly Val Val Ser 
1               5                   10                  15      


Val Ser Trp Gly Glu Asn Thr Val Met Ser Cys Asn Ile Ser Asn Ala 
            20                  25                  30          


Phe Ser His Val Asn Ile Lys Leu Arg Ala His Gly Gln Glu Ser Ala 
        35                  40                  45              


Ile Phe Asn Glu Val Ala Pro Gly Tyr Phe Ser Arg Asp Gly Trp Gln 
    50                  55                  60                  


Leu Gln Val Gln Gly Gly Val Ala Gln Leu Val Ile Lys Gly Ala Arg 
65                  70                  75                  80  


Asp Ser His Ala Gly Leu Tyr Met Trp His Leu Val Gly His Gln Arg 
                85                  90                  95      


Asn Asn Arg Gln Val Thr Leu Glu Val Ser Gly Ala Glu Pro Gln Ser 
            100                 105                 110         


Ala Pro Asp Thr Gly 
        115         


<210>  1169
<211>  535
<212>  PRT
<213>  Homo Sapiens

<400>  1169

Trp Ser Tyr Asn Thr Ser Thr Glu Ala Met Thr Tyr Asp Glu Ala Ser 
1               5                   10                  15      


Ala Tyr Cys Gln Gln Arg Tyr Thr His Leu Val Ala Ile Gln Asn Lys 
            20                  25                  30          


Glu Glu Ile Glu Tyr Leu Asn Ser Ile Leu Ser Tyr Ser Pro Ser Tyr 
        35                  40                  45              


Tyr Trp Ile Gly Ile Arg Lys Val Asn Asn Val Trp Val Trp Val Gly 
    50                  55                  60                  


Thr Gln Lys Pro Leu Thr Glu Glu Ala Lys Asn Trp Ala Pro Gly Glu 
65                  70                  75                  80  


Pro Asn Asn Arg Gln Lys Asp Glu Asp Cys Val Glu Ile Tyr Ile Lys 
                85                  90                  95      


Arg Glu Lys Asp Val Gly Met Trp Asn Asp Glu Arg Cys Ser Lys Lys 
            100                 105                 110         


Lys Leu Ala Leu Cys Tyr Thr Ala Ala Cys Thr Asn Thr Ser Cys Ser 
        115                 120                 125             


Gly His Gly Glu Cys Val Glu Thr Ile Asn Asn Tyr Thr Cys Lys Cys 
    130                 135                 140                 


Asp Pro Gly Phe Ser Gly Leu Lys Cys Glu Gln Ile Val Asn Cys Thr 
145                 150                 155                 160 


Ala Leu Glu Ser Pro Glu His Gly Ser Leu Val Cys Ser His Pro Leu 
                165                 170                 175     


Gly Asn Phe Ser Tyr Asn Ser Ser Cys Ser Ile Ser Cys Asp Arg Gly 
            180                 185                 190         


Tyr Leu Pro Ser Ser Met Glu Thr Met Gln Cys Met Ser Ser Gly Glu 
        195                 200                 205             


Trp Ser Ala Pro Ile Pro Ala Cys Asn Val Val Glu Cys Asp Ala Val 
    210                 215                 220                 


Thr Asn Pro Ala Asn Gly Phe Val Glu Cys Phe Gln Asn Pro Gly Ser 
225                 230                 235                 240 


Phe Pro Trp Asn Thr Thr Cys Thr Phe Asp Cys Glu Glu Gly Phe Glu 
                245                 250                 255     


Leu Met Gly Ala Gln Ser Leu Gln Cys Thr Ser Ser Gly Asn Trp Asp 
            260                 265                 270         


Asn Glu Lys Pro Thr Cys Lys Ala Val Thr Cys Arg Ala Val Arg Gln 
        275                 280                 285             


Pro Gln Asn Gly Ser Val Arg Cys Ser His Ser Pro Ala Gly Glu Phe 
    290                 295                 300                 


Thr Phe Lys Ser Ser Cys Asn Phe Thr Cys Glu Glu Gly Phe Met Leu 
305                 310                 315                 320 


Gln Gly Pro Ala Gln Val Glu Cys Thr Thr Gln Gly Gln Trp Thr Gln 
                325                 330                 335     


Gln Ile Pro Val Cys Glu Ala Phe Gln Cys Thr Ala Leu Ser Asn Pro 
            340                 345                 350         


Glu Arg Gly Tyr Met Asn Cys Leu Pro Ser Ala Ser Gly Ser Phe Arg 
        355                 360                 365             


Tyr Gly Ser Ser Cys Glu Phe Ser Cys Glu Gln Gly Phe Val Leu Lys 
    370                 375                 380                 


Gly Ser Lys Arg Leu Gln Cys Gly Pro Thr Gly Glu Trp Asp Asn Glu 
385                 390                 395                 400 


Lys Pro Thr Cys Glu Ala Val Arg Cys Asp Ala Val His Gln Pro Pro 
                405                 410                 415     


Lys Gly Leu Val Arg Cys Ala His Ser Pro Ile Gly Glu Phe Thr Tyr 
            420                 425                 430         


Lys Ser Ser Cys Ala Phe Ser Cys Glu Glu Gly Phe Glu Leu His Gly 
        435                 440                 445             


Ser Thr Gln Leu Glu Cys Thr Ser Gln Gly Gln Trp Thr Glu Glu Val 
    450                 455                 460                 


Pro Ser Cys Gln Val Val Lys Cys Ser Ser Leu Ala Val Pro Gly Lys 
465                 470                 475                 480 


Ile Asn Met Ser Cys Ser Gly Glu Pro Val Phe Gly Thr Val Cys Lys 
                485                 490                 495     


Phe Ala Cys Pro Glu Gly Trp Thr Leu Asn Gly Ser Ala Ala Arg Thr 
            500                 505                 510         


Cys Gly Ala Thr Gly His Trp Ser Gly Leu Leu Pro Thr Cys Glu Ala 
        515                 520                 525             


Pro Thr Glu Ser Asn Ile Pro 
    530                 535 


<210>  1170
<211>  294
<212>  PRT
<213>  Homo Sapiens

<400>  1170

Trp Thr Tyr His Tyr Ser Glu Lys Pro Met Asn Trp Gln Arg Ala Arg 
1               5                   10                  15      


Arg Phe Cys Arg Asp Asn Tyr Thr Asp Leu Val Ala Ile Gln Asn Lys 
            20                  25                  30          


Ala Glu Ile Glu Tyr Leu Glu Lys Thr Leu Pro Phe Ser Arg Ser Tyr 
        35                  40                  45              


Tyr Trp Ile Gly Ile Arg Lys Ile Gly Gly Ile Trp Thr Trp Val Gly 
    50                  55                  60                  


Thr Asn Lys Ser Leu Thr Glu Glu Ala Glu Asn Trp Gly Asp Gly Glu 
65                  70                  75                  80  


Pro Asn Asn Lys Lys Asn Lys Glu Asp Cys Val Glu Ile Tyr Ile Lys 
                85                  90                  95      


Arg Asn Lys Asp Ala Gly Lys Trp Asn Asp Asp Ala Cys His Lys Leu 
            100                 105                 110         


Lys Ala Ala Leu Cys Tyr Thr Ala Ser Cys Gln Pro Trp Ser Cys Ser 
        115                 120                 125             


Gly His Gly Glu Cys Val Glu Ile Ile Asn Asn Tyr Thr Cys Asn Cys 
    130                 135                 140                 


Asp Val Gly Tyr Tyr Gly Pro Gln Cys Gln Phe Val Ile Gln Cys Glu 
145                 150                 155                 160 


Pro Leu Glu Ala Pro Glu Leu Gly Thr Met Asp Cys Thr His Pro Leu 
                165                 170                 175     


Gly Asn Phe Ser Phe Ser Ser Gln Cys Ala Phe Ser Cys Ser Glu Gly 
            180                 185                 190         


Thr Asn Leu Thr Gly Ile Glu Glu Thr Thr Cys Gly Pro Phe Gly Asn 
        195                 200                 205             


Trp Ser Ser Pro Glu Pro Thr Cys Gln Val Ile Gln Cys Glu Pro Leu 
    210                 215                 220                 


Ser Ala Pro Asp Leu Gly Ile Met Asn Cys Ser His Pro Leu Ala Ser 
225                 230                 235                 240 


Phe Ser Phe Thr Ser Ala Cys Thr Phe Ile Cys Ser Glu Gly Thr Glu 
                245                 250                 255     


Leu Ile Gly Lys Lys Lys Thr Ile Cys Glu Ser Ser Gly Ile Trp Ser 
            260                 265                 270         


Asn Pro Ser Pro Ile Cys Gln Lys Leu Asp Lys Ser Phe Ser Met Ile 
        275                 280                 285             


Lys Glu Gly Asp Tyr Asn 
    290                 


<210>  1171
<211>  729
<212>  PRT
<213>  Homo Sapiens

<400>  1171

Trp Thr Tyr His Tyr Ser Thr Lys Ala Tyr Ser Trp Asn Ile Ser Arg 
1               5                   10                  15      


Lys Tyr Cys Gln Asn Arg Tyr Thr Asp Leu Val Ala Ile Gln Asn Lys 
            20                  25                  30          


Asn Glu Ile Asp Tyr Leu Asn Lys Val Leu Pro Tyr Tyr Ser Ser Tyr 
        35                  40                  45              


Tyr Trp Ile Gly Ile Arg Lys Asn Asn Lys Thr Trp Thr Trp Val Gly 
    50                  55                  60                  


Thr Lys Lys Ala Leu Thr Asn Glu Ala Glu Asn Trp Ala Asp Asn Glu 
65                  70                  75                  80  


Pro Asn Asn Lys Arg Asn Asn Glu Asp Cys Val Glu Ile Tyr Ile Lys 
                85                  90                  95      


Ser Pro Ser Ala Pro Gly Lys Trp Asn Asp Glu His Cys Leu Lys Lys 
            100                 105                 110         


Lys His Ala Leu Cys Tyr Thr Ala Ser Cys Gln Asp Met Ser Cys Ser 
        115                 120                 125             


Lys Gln Gly Glu Cys Leu Glu Thr Ile Gly Asn Tyr Thr Cys Ser Cys 
    130                 135                 140                 


Tyr Pro Gly Phe Tyr Gly Pro Glu Cys Glu Tyr Val Arg Glu Cys Gly 
145                 150                 155                 160 


Glu Leu Glu Leu Pro Gln His Val Leu Met Asn Cys Ser His Pro Leu 
                165                 170                 175     


Gly Asn Phe Ser Phe Asn Ser Gln Cys Ser Phe His Cys Thr Asp Gly 
            180                 185                 190         


Tyr Gln Val Asn Gly Pro Ser Lys Leu Glu Cys Leu Ala Ser Gly Ile 
        195                 200                 205             


Trp Thr Asn Lys Pro Pro Gln Cys Leu Ala Ala Gln Cys Pro Pro Leu 
    210                 215                 220                 


Lys Ile Pro Glu Arg Gly Asn Met Thr Cys Leu His Ser Ala Lys Ala 
225                 230                 235                 240 


Phe Gln His Gln Ser Ser Cys Ser Phe Ser Cys Glu Glu Gly Phe Ala 
                245                 250                 255     


Leu Val Gly Pro Glu Val Val Gln Cys Thr Ala Ser Gly Val Trp Thr 
            260                 265                 270         


Ala Pro Ala Pro Val Cys Lys Ala Val Gln Cys Gln His Leu Glu Ala 
        275                 280                 285             


Pro Ser Glu Gly Thr Met Asp Cys Val His Pro Leu Thr Ala Phe Ala 
    290                 295                 300                 


Tyr Gly Ser Ser Cys Lys Phe Glu Cys Gln Pro Gly Tyr Arg Val Arg 
305                 310                 315                 320 


Gly Leu Asp Met Leu Arg Cys Ile Asp Ser Gly His Trp Ser Ala Pro 
                325                 330                 335     


Leu Pro Thr Cys Glu Ala Ile Ser Cys Glu Pro Leu Glu Ser Pro Val 
            340                 345                 350         


His Gly Ser Met Asp Cys Ser Pro Ser Leu Arg Ala Phe Gln Tyr Asp 
        355                 360                 365             


Thr Asn Cys Ser Phe Arg Cys Ala Glu Gly Phe Met Leu Arg Gly Ala 
    370                 375                 380                 


Asp Ile Val Arg Cys Asp Asn Leu Gly Gln Trp Thr Ala Pro Ala Pro 
385                 390                 395                 400 


Val Cys Gln Ala Leu Gln Cys Gln Asp Leu Pro Val Pro Asn Glu Ala 
                405                 410                 415     


Arg Val Asn Cys Ser His Pro Phe Gly Ala Phe Arg Tyr Gln Ser Val 
            420                 425                 430         


Cys Ser Phe Thr Cys Asn Glu Gly Leu Leu Leu Val Gly Ala Ser Val 
        435                 440                 445             


Leu Gln Cys Leu Ala Thr Gly Asn Trp Asn Ser Val Pro Pro Glu Cys 
    450                 455                 460                 


Gln Ala Ile Pro Cys Thr Pro Leu Leu Ser Pro Gln Asn Gly Thr Met 
465                 470                 475                 480 


Thr Cys Val Arg Pro Leu Gly Ser Ser Ser Tyr Lys Ser Thr Cys Gln 
                485                 490                 495     


Phe Ile Cys Asp Glu Gly Tyr Ser Leu Ser Gly Pro Glu Arg Leu Asp 
            500                 505                 510         


Cys Thr Arg Ser Gly Arg Trp Thr Asp Ser Pro Pro Met Cys Glu Ala 
        515                 520                 525             


Ile Lys Cys Pro Glu Leu Phe Ala Pro Glu Gln Gly Ser Leu Asp Cys 
    530                 535                 540                 


Ser Asp Thr Arg Gly Glu Phe Asn Val Gly Ser Thr Cys His Phe Ser 
545                 550                 555                 560 


Cys Asn Asn Gly Phe Lys Leu Glu Gly Pro Asn Asn Val Glu Cys Thr 
                565                 570                 575     


Thr Ser Gly Arg Trp Ser Ala Thr Pro Pro Thr Cys Lys Gly Ile Ala 
            580                 585                 590         


Ser Leu Pro Thr Pro Gly Val Gln Cys Pro Ala Leu Thr Thr Pro Gly 
        595                 600                 605             


Gln Gly Thr Met Tyr Cys Arg His His Pro Gly Thr Phe Gly Phe Asn 
    610                 615                 620                 


Thr Thr Cys Tyr Phe Gly Cys Asn Ala Gly Phe Thr Leu Ile Gly Asp 
625                 630                 635                 640 


Ser Thr Leu Ser Cys Arg Pro Ser Gly Gln Trp Thr Ala Val Thr Pro 
                645                 650                 655     


Ala Cys Arg Ala Val Lys Cys Ser Glu Leu His Val Asn Lys Pro Ile 
            660                 665                 670         


Ala Met Asn Cys Ser Asn Leu Trp Gly Asn Phe Ser Tyr Gly Ser Ile 
        675                 680                 685             


Cys Ser Phe His Cys Leu Glu Gly Gln Leu Leu Asn Gly Ser Ala Gln 
    690                 695                 700                 


Thr Ala Cys Gln Glu Asn Gly His Trp Ser Thr Thr Val Pro Thr Cys 
705                 710                 715                 720 


Gln Gly Pro Leu Thr Ile Gln Glu Ala 
                725                 


<210>  1172
<211>  751
<212>  PRT
<213>  Homo Sapiens

<400>  1172

Asn Tyr Gln Asn Gly Lys Asn Asn Val Pro Arg Leu Lys Leu Ser Tyr 
1               5                   10                  15      


Lys Glu Met Leu Glu Ser Asn Asn Val Ile Thr Phe Asn Gly Leu Ala 
            20                  25                  30          


Asn Ser Ser Ser Tyr His Thr Phe Leu Leu Asp Glu Glu Arg Ser Arg 
        35                  40                  45              


Leu Tyr Val Gly Ala Lys Asp His Ile Phe Ser Phe Asp Leu Val Asn 
    50                  55                  60                  


Ile Lys Asp Phe Gln Lys Ile Val Trp Pro Val Ser Tyr Thr Arg Arg 
65                  70                  75                  80  


Asp Glu Cys Lys Trp Ala Gly Lys Asp Ile Leu Lys Glu Cys Ala Asn 
                85                  90                  95      


Phe Ile Lys Val Leu Lys Ala Tyr Asn Gln Thr His Leu Tyr Ala Cys 
            100                 105                 110         


Gly Thr Gly Ala Phe His Pro Ile Cys Thr Tyr Ile Glu Ile Gly His 
        115                 120                 125             


His Pro Glu Asp Asn Ile Phe Lys Leu Glu Asn Ser His Phe Glu Asn 
    130                 135                 140                 


Gly Arg Gly Lys Ser Pro Tyr Asp Pro Lys Leu Leu Thr Ala Ser Leu 
145                 150                 155                 160 


Leu Ile Asp Gly Glu Leu Tyr Ser Gly Thr Ala Ala Asp Phe Met Gly 
                165                 170                 175     


Arg Asp Phe Ala Ile Phe Arg Thr Leu Gly His His His Pro Ile Arg 
            180                 185                 190         


Thr Glu Gln His Asp Ser Arg Trp Leu Asn Asp Pro Lys Phe Ile Ser 
        195                 200                 205             


Ala His Leu Ile Ser Glu Ser Asp Asn Pro Glu Asp Asp Lys Val Tyr 
    210                 215                 220                 


Phe Phe Phe Arg Glu Asn Ala Ile Asp Gly Glu His Ser Gly Lys Ala 
225                 230                 235                 240 


Thr His Ala Arg Ile Gly Gln Ile Cys Lys Asn Asp Phe Gly Gly His 
                245                 250                 255     


Arg Ser Leu Val Asn Lys Trp Thr Thr Phe Leu Lys Ala Arg Leu Ile 
            260                 265                 270         


Cys Ser Val Pro Gly Pro Asn Gly Ile Asp Thr His Phe Asp Glu Leu 
        275                 280                 285             


Gln Asp Val Phe Leu Met Asn Phe Lys Asp Pro Lys Asn Pro Val Val 
    290                 295                 300                 


Tyr Gly Val Phe Thr Thr Ser Ser Asn Ile Phe Lys Gly Ser Ala Val 
305                 310                 315                 320 


Cys Met Tyr Ser Met Ser Asp Val Arg Arg Val Phe Leu Gly Pro Tyr 
                325                 330                 335     


Ala His Arg Asp Gly Pro Asn Tyr Gln Trp Val Pro Tyr Gln Gly Arg 
            340                 345                 350         


Val Pro Tyr Pro Arg Pro Gly Thr Cys Pro Ser Lys Thr Phe Gly Gly 
        355                 360                 365             


Phe Asp Ser Thr Lys Asp Leu Pro Asp Asp Val Ile Thr Phe Ala Arg 
    370                 375                 380                 


Ser His Pro Ala Met Tyr Asn Pro Val Phe Pro Met Asn Asn Arg Pro 
385                 390                 395                 400 


Ile Val Ile Lys Thr Asp Val Asn Tyr Gln Phe Thr Gln Ile Val Val 
                405                 410                 415     


Asp Arg Val Asp Ala Glu Asp Gly Gln Tyr Asp Val Met Phe Ile Gly 
            420                 425                 430         


Thr Asp Val Gly Thr Val Leu Lys Val Val Ser Ile Pro Lys Glu Thr 
        435                 440                 445             


Trp Tyr Asp Leu Glu Glu Val Leu Leu Glu Glu Met Thr Val Phe Arg 
    450                 455                 460                 


Glu Pro Thr Ala Ile Ser Ala Met Glu Leu Ser Thr Lys Gln Gln Gln 
465                 470                 475                 480 


Leu Tyr Ile Gly Ser Thr Ala Gly Val Ala Gln Leu Pro Leu His Arg 
                485                 490                 495     


Cys Asp Ile Tyr Gly Lys Ala Cys Ala Glu Cys Cys Leu Ala Arg Asp 
            500                 505                 510         


Pro Tyr Cys Ala Trp Asp Gly Ser Ala Cys Ser Arg Tyr Phe Pro Thr 
        515                 520                 525             


Ala Lys Arg Arg Thr Arg Arg Gln Asp Ile Arg Asn Gly Asp Pro Leu 
    530                 535                 540                 


Thr His Cys Ser Asp Leu His His Asp Asn His His Gly His Ser Pro 
545                 550                 555                 560 


Glu Glu Arg Ile Ile Tyr Gly Val Glu Asn Ser Ser Thr Phe Leu Glu 
                565                 570                 575     


Cys Ser Pro Lys Ser Gln Arg Ala Leu Val Tyr Trp Gln Phe Gln Arg 
            580                 585                 590         


Arg Asn Glu Glu Arg Lys Glu Glu Ile Arg Val Asp Asp His Ile Ile 
        595                 600                 605             


Arg Thr Asp Gln Gly Leu Leu Leu Arg Ser Leu Gln Gln Lys Asp Ser 
    610                 615                 620                 


Gly Asn Tyr Leu Cys His Ala Val Glu His Gly Phe Ile Gln Thr Leu 
625                 630                 635                 640 


Leu Lys Val Thr Leu Glu Val Ile Asp Thr Glu His Leu Glu Glu Leu 
                645                 650                 655     


Leu His Lys Asp Asp Asp Gly Asp Gly Ser Lys Thr Lys Glu Met Ser 
            660                 665                 670         


Asn Ser Met Thr Pro Ser Gln Lys Val Trp Tyr Arg Asp Phe Met Gln 
        675                 680                 685             


Leu Ile Asn His Pro Asn Leu Asn Thr Met Asp Glu Phe Cys Glu Gln 
    690                 695                 700                 


Val Trp Lys Arg Asp Arg Lys Gln Arg Arg Gln Arg Pro Gly His Thr 
705                 710                 715                 720 


Pro Gly Asn Ser Asn Lys Trp Lys His Leu Gln Glu Asn Lys Lys Gly 
                725                 730                 735     


Arg Asn Arg Arg Thr His Glu Phe Glu Arg Ala Pro Arg Ser Val 
            740                 745                 750     


<210>  1173
<211>  724
<212>  PRT
<213>  Homo Sapiens

<400>  1173

Ala Pro Ser Pro Pro Arg Leu Arg Leu Ser Phe Gln Glu Leu Gln Ala 
1               5                   10                  15      


Trp His Gly Leu Gln Thr Phe Ser Leu Glu Arg Thr Cys Cys Tyr Gln 
            20                  25                  30          


Ala Leu Leu Val Asp Glu Glu Arg Gly Arg Leu Phe Val Gly Ala Glu 
        35                  40                  45              


Asn His Val Ala Ser Leu Asn Leu Asp Asn Ile Ser Lys Arg Ala Lys 
    50                  55                  60                  


Lys Leu Ala Trp Pro Ala Pro Val Glu Trp Arg Glu Glu Cys Asn Trp 
65                  70                  75                  80  


Ala Gly Lys Asp Ile Gly Thr Glu Cys Met Asn Phe Val Lys Leu Leu 
                85                  90                  95      


His Ala Tyr Asn Arg Thr His Leu Leu Ala Cys Gly Thr Gly Ala Phe 
            100                 105                 110         


His Pro Thr Cys Ala Phe Val Glu Val Gly His Arg Ala Glu Glu Pro 
        115                 120                 125             


Val Leu Arg Leu Asp Pro Gly Arg Ile Glu Asp Gly Lys Gly Lys Ser 
    130                 135                 140                 


Pro Tyr Asp Pro Arg His Arg Ala Ala Ser Val Leu Val Gly Glu Glu 
145                 150                 155                 160 


Leu Tyr Ser Gly Val Ala Ala Asp Leu Met Gly Arg Asp Phe Thr Ile 
                165                 170                 175     


Phe Arg Ser Leu Gly Gln Arg Pro Ser Leu Arg Thr Glu Pro His Asp 
            180                 185                 190         


Ser Arg Trp Leu Asn Glu Pro Lys Phe Val Lys Val Phe Trp Ile Pro 
        195                 200                 205             


Glu Ser Glu Asn Pro Asp Asp Asp Lys Ile Tyr Phe Phe Phe Arg Glu 
    210                 215                 220                 


Thr Ala Val Glu Ala Ala Pro Ala Leu Gly Arg Leu Ser Val Ser Arg 
225                 230                 235                 240 


Val Gly Gln Ile Cys Arg Asn Asp Val Gly Gly Gln Arg Ser Leu Val 
                245                 250                 255     


Asn Lys Trp Thr Thr Phe Leu Lys Ala Arg Leu Val Cys Ser Val Pro 
            260                 265                 270         


Gly Val Glu Gly Asp Thr His Phe Asp Gln Leu Gln Asp Val Phe Leu 
        275                 280                 285             


Leu Ser Ser Arg Asp His Arg Thr Pro Leu Leu Tyr Ala Val Phe Ser 
    290                 295                 300                 


Thr Ser Ser Ile Phe Gln Gly Ser Ala Val Cys Val Tyr Ser Met Asn 
305                 310                 315                 320 


Asp Val Arg Arg Ala Phe Leu Gly Pro Phe Ala His Lys Glu Gly Pro 
                325                 330                 335     


Met His Gln Trp Val Ser Tyr Gln Gly Arg Val Pro Tyr Pro Arg Pro 
            340                 345                 350         


Gly Met Cys Pro Ser Lys Thr Phe Gly Thr Phe Ser Ser Thr Lys Asp 
        355                 360                 365             


Phe Pro Asp Asp Val Ile Gln Phe Ala Arg Asn His Pro Leu Met Tyr 
    370                 375                 380                 


Asn Ser Val Leu Pro Thr Gly Gly Arg Pro Leu Phe Leu Gln Val Gly 
385                 390                 395                 400 


Ala Asn Tyr Thr Phe Thr Gln Ile Ala Ala Asp Arg Val Ala Ala Ala 
                405                 410                 415     


Asp Gly His Tyr Asp Val Leu Phe Ile Gly Thr Asp Val Gly Thr Val 
            420                 425                 430         


Leu Lys Val Ile Ser Val Pro Lys Gly Ser Arg Pro Ser Ala Glu Gly 
        435                 440                 445             


Leu Leu Leu Glu Glu Leu His Val Phe Glu Asp Ser Ala Ala Val Thr 
    450                 455                 460                 


Ser Met Gln Ile Ser Ser Lys Arg His Gln Leu Tyr Val Ala Ser Arg 
465                 470                 475                 480 


Ser Ala Val Ala Gln Ile Ala Leu His Arg Cys Ala Ala His Gly Arg 
                485                 490                 495     


Val Cys Thr Glu Cys Cys Leu Ala Arg Asp Pro Tyr Cys Ala Trp Asp 
            500                 505                 510         


Gly Val Ala Cys Thr Arg Phe Gln Pro Ser Ala Lys Arg Arg Phe Arg 
        515                 520                 525             


Arg Gln Asp Val Arg Asn Gly Asp Pro Ser Thr Leu Cys Ser Gly Asp 
    530                 535                 540                 


Ser Ser Arg Pro Ala Leu Leu Glu His Lys Val Phe Gly Val Glu Gly 
545                 550                 555                 560 


Ser Ser Ala Phe Leu Glu Cys Glu Pro Arg Ser Leu Gln Ala Arg Val 
                565                 570                 575     


Glu Trp Thr Phe Gln Arg Ala Gly Val Thr Ala His Thr Gln Val Leu 
            580                 585                 590         


Ala Glu Glu Arg Thr Glu Arg Thr Ala Arg Gly Leu Leu Leu Arg Arg 
        595                 600                 605             


Leu Arg Arg Arg Asp Ser Gly Val Tyr Leu Cys Ala Ala Val Glu Gln 
    610                 615                 620                 


Gly Phe Thr Gln Pro Leu Arg Arg Leu Ser Leu His Val Leu Ser Ala 
625                 630                 635                 640 


Thr Gln Ala Glu Arg Leu Ala Arg Ala Glu Glu Ala Ala Pro Ala Ala 
                645                 650                 655     


Pro Pro Gly Pro Lys Leu Trp Tyr Arg Asp Phe Leu Gln Leu Val Glu 
            660                 665                 670         


Pro Gly Gly Gly Gly Ser Ala Asn Ser Leu Arg Met Cys Arg Pro Gln 
        675                 680                 685             


Pro Ala Leu Gln Ser Leu Pro Leu Glu Ser Arg Arg Lys Gly Arg Asn 
    690                 695                 700                 


Arg Arg Thr His Ala Pro Glu Pro Arg Ala Glu Arg Gly Pro Arg Ser 
705                 710                 715                 720 


Ala Thr His Trp 
                


<210>  1174
<211>  731
<212>  PRT
<213>  Homo Sapiens

<400>  1174

Gly Ser Ser Gln Pro Gln Ala Arg Val Tyr Leu Thr Phe Asp Glu Leu 
1               5                   10                  15      


Arg Glu Thr Lys Thr Ser Glu Tyr Phe Ser Leu Ser His His Pro Leu 
            20                  25                  30          


Asp Tyr Arg Ile Leu Leu Met Asp Glu Asp Gln Asp Arg Ile Tyr Val 
        35                  40                  45              


Gly Ser Lys Asp His Ile Leu Ser Leu Asn Ile Asn Asn Ile Ser Gln 
    50                  55                  60                  


Glu Ala Leu Ser Val Phe Trp Pro Ala Ser Thr Ile Lys Val Glu Glu 
65                  70                  75                  80  


Cys Lys Met Ala Gly Lys Asp Pro Thr His Gly Cys Gly Asn Phe Val 
                85                  90                  95      


Arg Val Ile Gln Thr Phe Asn Arg Thr His Leu Tyr Val Cys Gly Ser 
            100                 105                 110         


Gly Ala Phe Ser Pro Val Cys Thr Tyr Leu Asn Arg Gly Arg Arg Ser 
        115                 120                 125             


Glu Asp Gln Val Phe Met Ile Asp Ser Lys Cys Glu Ser Gly Lys Gly 
    130                 135                 140                 


Arg Cys Ser Phe Asn Pro Asn Val Asn Thr Val Ser Val Met Ile Asn 
145                 150                 155                 160 


Glu Glu Leu Phe Ser Gly Met Tyr Ile Asp Phe Met Gly Thr Asp Ala 
                165                 170                 175     


Ala Ile Phe Arg Ser Leu Thr Lys Arg Asn Ala Val Arg Thr Asp Gln 
            180                 185                 190         


His Asn Ser Lys Trp Leu Ser Glu Pro Met Phe Val Asp Ala His Val 
        195                 200                 205             


Ile Pro Asp Gly Thr Asp Pro Asn Asp Ala Lys Val Tyr Phe Phe Phe 
    210                 215                 220                 


Lys Glu Lys Leu Thr Asp Asn Asn Arg Ser Thr Lys Gln Ile His Ser 
225                 230                 235                 240 


Met Ile Ala Arg Ile Cys Pro Asn Asp Thr Gly Gly Leu Arg Ser Leu 
                245                 250                 255     


Val Asn Lys Trp Thr Thr Phe Leu Lys Ala Arg Leu Val Cys Ser Val 
            260                 265                 270         


Thr Asp Glu Asp Gly Pro Glu Thr His Phe Asp Glu Leu Glu Asp Val 
        275                 280                 285             


Phe Leu Leu Glu Thr Asp Asn Pro Arg Thr Thr Leu Val Tyr Gly Ile 
    290                 295                 300                 


Phe Thr Thr Ser Ser Ser Val Phe Lys Gly Ser Ala Val Cys Val Tyr 
305                 310                 315                 320 


His Leu Ser Asp Ile Gln Thr Val Phe Asn Gly Pro Phe Ala His Lys 
                325                 330                 335     


Glu Gly Pro Asn His Gln Leu Ile Ser Tyr Gln Gly Arg Ile Pro Tyr 
            340                 345                 350         


Pro Arg Pro Gly Thr Cys Pro Gly Gly Ala Phe Thr Pro Asn Met Arg 
        355                 360                 365             


Thr Thr Lys Glu Phe Pro Asp Asp Val Val Thr Phe Ile Arg Asn His 
    370                 375                 380                 


Pro Leu Met Tyr Asn Ser Ile Tyr Pro Ile His Lys Arg Pro Leu Ile 
385                 390                 395                 400 


Val Arg Ile Gly Thr Asp Tyr Lys Tyr Thr Lys Ile Ala Val Asp Arg 
                405                 410                 415     


Val Asn Ala Ala Asp Gly Arg Tyr His Val Leu Phe Leu Gly Thr Asp 
            420                 425                 430         


Arg Gly Thr Val Gln Lys Val Val Val Leu Pro Thr Asn Asn Ser Val 
        435                 440                 445             


Ser Gly Glu Leu Ile Leu Glu Glu Leu Glu Val Phe Lys Asn His Ala 
    450                 455                 460                 


Pro Ile Thr Thr Met Lys Ile Ser Ser Lys Lys Gln Gln Leu Tyr Val 
465                 470                 475                 480 


Ser Ser Asn Glu Gly Val Ser Gln Val Ser Leu His Arg Cys His Ile 
                485                 490                 495     


Tyr Gly Thr Ala Cys Ala Asp Cys Cys Leu Ala Arg Asp Pro Tyr Cys 
            500                 505                 510         


Ala Trp Asp Gly His Ser Cys Ser Arg Phe Tyr Pro Thr Gly Lys Arg 
        515                 520                 525             


Arg Ser Arg Arg Gln Asp Val Arg His Gly Asn Pro Leu Thr Gln Cys 
    530                 535                 540                 


Arg Gly Phe Asn Leu Lys Ala Tyr Arg Asn Ala Ala Glu Ile Val Gln 
545                 550                 555                 560 


Tyr Gly Val Lys Asn Asn Thr Thr Phe Leu Glu Cys Ala Pro Lys Ser 
                565                 570                 575     


Pro Gln Ala Ser Ile Lys Trp Leu Leu Gln Lys Asp Lys Asp Arg Arg 
            580                 585                 590         


Lys Glu Val Lys Leu Asn Glu Arg Ile Ile Ala Thr Ser Gln Gly Leu 
        595                 600                 605             


Leu Ile Arg Ser Val Gln Gly Ser Asp Gln Gly Leu Tyr His Cys Ile 
    610                 615                 620                 


Ala Thr Glu Asn Ser Phe Lys Gln Thr Ile Ala Lys Ile Asn Phe Lys 
625                 630                 635                 640 


Val Leu Asp Ser Glu Met Val Ala Val Val Thr Asp Lys Trp Ser Pro 
                645                 650                 655     


Trp Thr Trp Ala Ser Ser Val Arg Ala Leu Pro Phe His Pro Lys Asp 
            660                 665                 670         


Ile Met Gly Ala Phe Ser His Ser Glu Met Gln Met Ile Asn Gln Tyr 
        675                 680                 685             


Cys Lys Asp Thr Arg Gln Gln His Gln Gln Gly Asp Glu Ser Gln Lys 
    690                 695                 700                 


Met Arg Gly Asp Tyr Gly Lys Leu Lys Ala Leu Ile Asn Ser Arg Lys 
705                 710                 715                 720 


Ser Arg Asn Arg Arg Asn Gln Leu Pro Glu Ser 
                725                 730     


<210>  1175
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  1175

Arg Cys Asp Thr Tyr Gly Lys Ala Cys Ala Asp Cys Cys Leu Ala Arg 
1               5                   10                  15      


Asp Pro Tyr Cys Ala Trp Asp Gly Asn Ala Cys Ser Arg Tyr Ala Pro 
            20                  25                  30          


Thr Ser Lys Arg Arg Ala Arg Arg Gln Asp Val Lys Tyr Gly Asp Pro 
        35                  40                  45              


Ile Thr Gln Cys Trp Asp Ile Glu Asp Ser Ile Ser His Glu Thr Ala 
    50                  55                  60                  


Asp Glu Lys Val Ile Phe Gly Ile Glu Phe Asn Ser Thr Phe Leu Glu 
65                  70                  75                  80  


Cys Ile Pro Lys Ser Gln Gln Ala Thr Ile Lys Trp Tyr Ile Gln Arg 
                85                  90                  95      


Ser Gly Asp Glu His Arg Glu Glu Leu Lys Pro Asp Glu Arg Ile Ile 
            100                 105                 110         


Lys Thr Glu Tyr Gly Leu Leu Ile Arg Ser Leu Gln Lys Lys Asp Ser 
        115                 120                 125             


Gly Met Tyr Tyr Cys Lys Ala Gln Glu His Thr Phe Ile His Thr Ile 
    130                 135                 140                 


Val Lys Leu Thr Leu Asn Val Ile Glu Asn Glu Gln Met Glu Asn Thr 
145                 150                 155                 160 


Gln Arg Ala Glu His Glu Glu Gly Lys Val Lys Asp Leu Leu Ala Glu 
                165                 170                 175     


Ser Arg Leu Arg Tyr Lys Asp Tyr Ile Gln Ile Leu Ser Ser Pro Asn 
            180                 185                 190         


Phe Ser Leu Asp Gln Tyr Cys Glu Gln Met Trp His Arg Glu Lys Arg 
        195                 200                 205             


Arg Gln Arg Asn Lys Gly Gly Pro Lys Trp Lys His Met Gln Glu Met 
    210                 215                 220                 


Lys Lys Lys Arg Asn Arg Arg His His Arg Asp Leu Asp Glu Leu Pro 
225                 230                 235                 240 


Arg Ala Val Ala Thr 
                245 


<210>  1176
<211>  750
<212>  PRT
<213>  Homo Sapiens

<400>  1176

Ala Asp Thr Thr His Pro Arg Leu Arg Leu Ser His Lys Glu Leu Leu 
1               5                   10                  15      


Asn Leu Asn Arg Thr Ser Ile Phe His Ser Pro Phe Gly Phe Leu Asp 
            20                  25                  30          


Leu His Thr Met Leu Leu Asp Glu Tyr Gln Glu Arg Leu Phe Val Gly 
        35                  40                  45              


Gly Arg Asp Leu Val Tyr Ser Leu Ser Leu Glu Arg Ile Ser Asp Gly 
    50                  55                  60                  


Tyr Lys Glu Ile His Trp Pro Ser Thr Ala Leu Lys Met Glu Glu Cys 
65                  70                  75                  80  


Ile Met Lys Gly Lys Asp Ala Gly Glu Cys Ala Asn Tyr Val Arg Val 
                85                  90                  95      


Leu His His Tyr Asn Arg Thr His Leu Leu Thr Cys Gly Thr Gly Ala 
            100                 105                 110         


Phe Asp Pro Val Cys Ala Phe Ile Arg Val Gly Tyr His Leu Glu Asp 
        115                 120                 125             


Pro Leu Phe His Leu Glu Ser Pro Arg Ser Glu Arg Gly Arg Gly Arg 
    130                 135                 140                 


Cys Pro Phe Asp Pro Ser Ser Ser Phe Ile Ser Thr Leu Ile Gly Ser 
145                 150                 155                 160 


Glu Leu Phe Ala Gly Leu Tyr Ser Asp Tyr Trp Ser Arg Asp Ala Ala 
                165                 170                 175     


Ile Phe Arg Ser Met Gly Arg Leu Ala His Ile Arg Thr Glu His Asp 
            180                 185                 190         


Asp Glu Arg Leu Leu Lys Glu Pro Lys Phe Val Gly Ser Tyr Met Ile 
        195                 200                 205             


Pro Asp Asn Glu Asp Arg Asp Asp Asn Lys Val Tyr Phe Phe Phe Thr 
    210                 215                 220                 


Glu Lys Ala Leu Glu Ala Glu Asn Asn Ala His Ala Ile Tyr Thr Arg 
225                 230                 235                 240 


Val Gly Arg Leu Cys Val Asn Asp Val Gly Gly Gln Arg Ile Leu Val 
                245                 250                 255     


Asn Lys Trp Ser Thr Phe Leu Lys Ala Arg Leu Val Cys Ser Val Pro 
            260                 265                 270         


Gly Met Asn Gly Ile Asp Thr Tyr Phe Asp Glu Leu Glu Asp Val Phe 
        275                 280                 285             


Leu Leu Pro Thr Arg Asp His Lys Asn Pro Val Ile Phe Gly Leu Phe 
    290                 295                 300                 


Asn Thr Thr Ser Asn Ile Phe Arg Gly His Ala Ile Cys Val Tyr His 
305                 310                 315                 320 


Met Ser Ser Ile Arg Ala Ala Phe Asn Gly Pro Tyr Ala His Lys Glu 
                325                 330                 335     


Gly Pro Glu Tyr His Trp Ser Val Tyr Glu Gly Lys Val Pro Tyr Pro 
            340                 345                 350         


Arg Pro Gly Ser Cys Ala Ser Lys Val Asn Gly Gly Arg Tyr Gly Thr 
        355                 360                 365             


Thr Lys Asp Tyr Pro Asp Asp Ala Ile Arg Phe Ala Arg Ser His Pro 
    370                 375                 380                 


Leu Met Tyr Gln Ala Ile Lys Pro Ala His Lys Lys Pro Ile Leu Val 
385                 390                 395                 400 


Lys Thr Asp Gly Lys Tyr Asn Leu Lys Gln Ile Ala Val Asp Arg Val 
                405                 410                 415     


Glu Ala Glu Asp Gly Gln Tyr Asp Val Leu Phe Ile Gly Thr Asp Asn 
            420                 425                 430         


Gly Ile Val Leu Lys Val Ile Thr Ile Tyr Asn Gln Glu Met Glu Ser 
        435                 440                 445             


Met Glu Glu Val Ile Leu Glu Glu Leu Gln Ile Phe Lys Asp Pro Val 
    450                 455                 460                 


Pro Ile Ile Ser Met Glu Ile Ser Ser Lys Arg Gln Gln Leu Tyr Ile 
465                 470                 475                 480 


Gly Ser Ala Ser Ala Val Ala Gln Val Arg Phe His His Cys Asp Met 
                485                 490                 495     


Tyr Gly Ser Ala Cys Ala Asp Cys Cys Leu Ala Arg Asp Pro Tyr Cys 
            500                 505                 510         


Ala Trp Asp Gly Ile Ser Cys Ser Arg Tyr Tyr Pro Thr Gly Thr His 
        515                 520                 525             


Ala Lys Arg Arg Phe Arg Arg Gln Asp Val Arg His Gly Asn Ala Ala 
    530                 535                 540                 


Gln Gln Cys Phe Gly Gln Gln Phe Val Gly Asp Ala Leu Asp Lys Thr 
545                 550                 555                 560 


Glu Glu His Leu Ala Tyr Gly Ile Glu Asn Asn Ser Thr Leu Leu Glu 
                565                 570                 575     


Cys Thr Pro Arg Ser Leu Gln Ala Lys Val Ile Trp Phe Val Gln Lys 
            580                 585                 590         


Gly Arg Glu Thr Arg Lys Glu Glu Val Lys Thr Asp Asp Arg Val Val 
        595                 600                 605             


Lys Met Asp Leu Gly Leu Leu Phe Leu Arg Leu His Lys Ser Asp Ala 
    610                 615                 620                 


Gly Thr Tyr Phe Cys Gln Thr Val Glu His Ser Phe Val His Thr Val 
625                 630                 635                 640 


Arg Lys Ile Thr Leu Glu Val Val Glu Glu Glu Lys Val Glu Asp Met 
                645                 650                 655     


Phe Asn Lys Asp Asp Glu Glu Asp Arg His His Arg Met Pro Cys Pro 
            660                 665                 670         


Ala Gln Ser Ser Ile Ser Gln Gly Ala Lys Pro Trp Tyr Lys Glu Phe 
        675                 680                 685             


Leu Gln Leu Ile Gly Tyr Ser Asn Phe Gln Arg Val Glu Glu Tyr Cys 
    690                 695                 700                 


Glu Lys Val Trp Cys Thr Asp Arg Lys Arg Lys Lys Leu Lys Met Ser 
705                 710                 715                 720 


Pro Ser Lys Trp Lys Tyr Ala Asn Pro Gln Glu Lys Lys Leu Arg Ser 
                725                 730                 735     


Lys Pro Glu His Tyr Arg Leu Pro Arg His Thr Leu Asp Ser 
            740                 745                 750 


<210>  1177
<211>  767
<212>  PRT
<213>  Homo Sapiens

<400>  1177

Ser Phe Pro Thr Gln Asp His Leu Pro Ala Thr Pro Arg Val Arg Leu 
1               5                   10                  15      


Ser Phe Lys Glu Leu Lys Ala Thr Gly Thr Ala His Phe Phe Asn Phe 
            20                  25                  30          


Leu Leu Asn Thr Thr Asp Tyr Arg Ile Leu Leu Lys Asp Glu Asp His 
        35                  40                  45              


Asp Arg Met Tyr Val Gly Ser Lys Asp Tyr Val Leu Ser Leu Asp Leu 
    50                  55                  60                  


His Asp Ile Asn Arg Glu Pro Leu Ile Ile His Trp Ala Ala Ser Pro 
65                  70                  75                  80  


Gln Arg Ile Glu Glu Cys Val Leu Ser Gly Lys Asp Val Asn Gly Glu 
                85                  90                  95      


Cys Gly Asn Phe Val Arg Leu Ile Gln Pro Trp Asn Arg Thr His Leu 
            100                 105                 110         


Tyr Val Cys Gly Thr Gly Ala Tyr Asn Pro Met Cys Thr Tyr Val Asn 
        115                 120                 125             


Arg Gly Arg Arg Ala Gln Ala Thr Pro Trp Thr Gln Thr Gln Ala Val 
    130                 135                 140                 


Arg Gly Arg Gly Ser Arg Ala Thr Asp Gly Ala Leu Arg Pro Met Pro 
145                 150                 155                 160 


Thr Ala Pro Arg Gln Asp Tyr Ile Phe Tyr Leu Glu Pro Glu Arg Leu 
                165                 170                 175     


Glu Ser Gly Lys Gly Lys Cys Pro Tyr Asp Pro Lys Leu Asp Thr Ala 
            180                 185                 190         


Ser Ala Leu Ile Asn Glu Glu Leu Tyr Ala Gly Val Tyr Ile Asp Phe 
        195                 200                 205             


Met Gly Thr Asp Ala Ala Ile Phe Arg Thr Leu Gly Lys Gln Thr Ala 
    210                 215                 220                 


Met Arg Thr Asp Gln Tyr Asn Ser Arg Trp Leu Asn Asp Pro Ser Phe 
225                 230                 235                 240 


Ile His Ala Glu Leu Ile Pro Asp Ser Ala Glu Arg Asn Asp Asp Lys 
                245                 250                 255     


Leu Tyr Phe Phe Phe Arg Glu Arg Ser Ala Glu Ala Pro Gln Ser Pro 
            260                 265                 270         


Ala Val Tyr Ala Arg Ile Gly Arg Ile Cys Leu Asn Asp Asp Gly Gly 
        275                 280                 285             


His Cys Cys Leu Val Asn Lys Trp Ser Thr Phe Leu Lys Ala Arg Leu 
    290                 295                 300                 


Val Cys Ser Val Pro Gly Glu Asp Gly Ile Glu Thr His Phe Asp Glu 
305                 310                 315                 320 


Leu Gln Asp Val Phe Val Gln Gln Thr Gln Asp Val Arg Asn Pro Val 
                325                 330                 335     


Ile Tyr Ala Val Phe Thr Ser Ser Gly Ser Val Phe Arg Gly Ser Ala 
            340                 345                 350         


Val Cys Val Tyr Ser Met Ala Asp Ile Arg Met Val Phe Asn Gly Pro 
        355                 360                 365             


Phe Ala His Lys Glu Gly Pro Asn Tyr Gln Trp Met Pro Phe Ser Gly 
    370                 375                 380                 


Lys Met Pro Tyr Pro Arg Pro Gly Thr Cys Pro Gly Gly Thr Phe Thr 
385                 390                 395                 400 


Pro Ser Met Lys Ser Thr Lys Asp Tyr Pro Asp Glu Val Ile Asn Phe 
                405                 410                 415     


Met Arg Ser His Pro Leu Met Tyr Gln Ala Val Tyr Pro Leu Gln Arg 
            420                 425                 430         


Arg Pro Leu Val Val Arg Thr Gly Ala Pro Tyr Arg Leu Thr Thr Ile 
        435                 440                 445             


Ala Val Asp Gln Val Asp Ala Ala Asp Gly Arg Tyr Glu Val Leu Phe 
    450                 455                 460                 


Leu Gly Thr Asp Arg Gly Thr Val Gln Lys Val Ile Val Leu Pro Lys 
465                 470                 475                 480 


Asp Asp Gln Glu Met Glu Glu Leu Met Leu Glu Glu Val Glu Val Phe 
                485                 490                 495     


Lys Asp Pro Ala Pro Val Lys Thr Met Thr Ile Ser Ser Lys Arg Gln 
            500                 505                 510         


Gln Leu Tyr Val Ala Ser Ala Val Gly Val Thr His Leu Ser Leu His 
        515                 520                 525             


Arg Cys Gln Ala Tyr Gly Ala Ala Cys Ala Asp Cys Cys Leu Ala Arg 
    530                 535                 540                 


Asp Pro Tyr Cys Ala Trp Asp Gly Gln Ala Cys Ser Arg Tyr Thr Ala 
545                 550                 555                 560 


Ser Ser Lys Arg Arg Ser Arg Arg Gln Asp Val Arg His Gly Asn Pro 
                565                 570                 575     


Ile Arg Gln Cys Arg Gly Phe Asn Ser Asn Ala Asn Lys Asn Ala Val 
            580                 585                 590         


Glu Ser Val Gln Tyr Gly Val Ala Gly Ser Ala Ala Phe Leu Glu Cys 
        595                 600                 605             


Gln Pro Arg Ser Pro Gln Ala Thr Val Lys Trp Leu Phe Gln Arg Asp 
    610                 615                 620                 


Pro Gly Asp Arg Arg Arg Glu Ile Arg Ala Glu Asp Arg Phe Leu Arg 
625                 630                 635                 640 


Thr Glu Gln Gly Leu Leu Leu Arg Ala Leu Gln Leu Ser Asp Arg Gly 
                645                 650                 655     


Leu Tyr Ser Cys Thr Ala Thr Glu Asn Asn Phe Lys His Val Val Thr 
            660                 665                 670         


Arg Val Gln Leu His Val Leu Gly Arg Asp Ala Val His Ala Ala Leu 
        675                 680                 685             


Phe Pro Pro Leu Ser Met Ser Ala Pro Pro Pro Pro Gly Ala Gly Pro 
    690                 695                 700                 


Pro Thr Pro Pro Tyr Gln Glu Leu Ala Gln Leu Leu Ala Gln Pro Glu 
705                 710                 715                 720 


Val Gly Leu Ile His Gln Tyr Cys Gln Gly Tyr Trp Arg His Val Pro 
                725                 730                 735     


Pro Ser Pro Arg Glu Ala Pro Gly Ala Pro Arg Ser Pro Glu Pro Gln 
            740                 745                 750         


Asp Gln Lys Lys Pro Arg Asn Arg Arg His His Pro Pro Asp Thr 
        755                 760                 765         


<210>  1178
<211>  760
<212>  PRT
<213>  Homo Sapiens

<400>  1178

Gly Pro Ser Pro Gly Pro Ser Val Pro Arg Leu Arg Leu Ser Tyr Arg 
1               5                   10                  15      


Asp Leu Leu Ser Ala Asn Arg Ser Ala Ile Phe Leu Gly Pro Gln Gly 
            20                  25                  30          


Ser Leu Asn Leu Gln Ala Met Tyr Leu Asp Glu Tyr Arg Asp Arg Leu 
        35                  40                  45              


Phe Leu Gly Gly Leu Asp Ala Leu Tyr Ser Leu Arg Leu Asp Gln Ala 
    50                  55                  60                  


Trp Pro Asp Pro Arg Glu Val Leu Trp Pro Pro Gln Pro Gly Gln Arg 
65                  70                  75                  80  


Glu Glu Cys Val Arg Lys Gly Arg Asp Pro Leu Thr Glu Cys Ala Asn 
                85                  90                  95      


Phe Val Arg Val Leu Gln Pro His Asn Arg Thr His Leu Leu Ala Cys 
            100                 105                 110         


Gly Thr Gly Ala Phe Gln Pro Thr Cys Ala Leu Ile Thr Val Gly His 
        115                 120                 125             


Arg Gly Glu His Val Leu His Leu Glu Pro Gly Ser Val Glu Ser Gly 
    130                 135                 140                 


Arg Gly Arg Cys Pro His Glu Pro Ser Arg Pro Phe Ala Ser Thr Phe 
145                 150                 155                 160 


Ile Asp Gly Glu Leu Tyr Thr Gly Leu Thr Ala Asp Phe Leu Gly Arg 
                165                 170                 175     


Glu Ala Met Ile Phe Arg Ser Gly Gly Pro Arg Pro Ala Leu Arg Ser 
            180                 185                 190         


Asp Ser Asp Gln Ser Leu Leu His Asp Pro Arg Phe Val Met Ala Ala 
        195                 200                 205             


Arg Ile Pro Glu Asn Ser Asp Gln Asp Asn Asp Lys Val Tyr Phe Phe 
    210                 215                 220                 


Phe Ser Glu Thr Val Pro Ser Pro Asp Gly Gly Ser Asn His Val Thr 
225                 230                 235                 240 


Val Ser Arg Val Gly Arg Val Cys Val Asn Asp Ala Gly Gly Gln Arg 
                245                 250                 255     


Val Leu Val Asn Lys Trp Ser Thr Phe Leu Lys Ala Arg Leu Val Cys 
            260                 265                 270         


Ser Val Pro Gly Pro Gly Gly Ala Glu Thr His Phe Asp Gln Leu Glu 
        275                 280                 285             


Asp Val Phe Leu Leu Trp Pro Lys Ala Gly Lys Ser Leu Glu Val Tyr 
    290                 295                 300                 


Ala Leu Phe Ser Thr Val Ser Ala Val Phe Gln Gly Phe Ala Val Cys 
305                 310                 315                 320 


Val Tyr His Met Ala Asp Ile Trp Glu Val Phe Asn Gly Pro Phe Ala 
                325                 330                 335     


His Arg Asp Gly Pro Gln His Gln Trp Gly Pro Tyr Gly Gly Lys Val 
            340                 345                 350         


Pro Phe Pro Arg Pro Gly Val Cys Pro Ser Lys Met Thr Ala Gln Pro 
        355                 360                 365             


Gly Arg Pro Phe Gly Ser Thr Lys Asp Tyr Pro Asp Glu Val Leu Gln 
    370                 375                 380                 


Phe Ala Arg Ala His Pro Leu Met Phe Trp Pro Val Arg Pro Arg His 
385                 390                 395                 400 


Gly Arg Pro Val Leu Val Lys Thr His Leu Ala Gln Gln Leu His Gln 
                405                 410                 415     


Ile Val Val Asp Arg Val Glu Ala Glu Asp Gly Thr Tyr Asp Val Ile 
            420                 425                 430         


Phe Leu Gly Thr Asp Ser Gly Ser Val Leu Lys Val Ile Ala Leu Gln 
        435                 440                 445             


Ala Gly Gly Ser Ala Glu Pro Glu Glu Val Val Leu Glu Glu Leu Gln 
    450                 455                 460                 


Val Phe Lys Val Pro Thr Pro Ile Thr Glu Met Glu Ile Ser Val Lys 
465                 470                 475                 480 


Arg Gln Met Leu Tyr Val Gly Ser Arg Leu Gly Val Ala Gln Leu Arg 
                485                 490                 495     


Leu His Gln Cys Glu Thr Tyr Gly Thr Ala Cys Ala Glu Cys Cys Leu 
            500                 505                 510         


Ala Arg Asp Pro Tyr Cys Ala Trp Asp Gly Ala Ser Cys Thr His Tyr 
        515                 520                 525             


Arg Pro Ser Leu Gly Lys Arg Arg Phe Arg Arg Gln Asp Ile Arg His 
    530                 535                 540                 


Gly Asn Pro Ala Leu Gln Cys Leu Gly Gln Ser Gln Glu Glu Glu Ala 
545                 550                 555                 560 


Val Gly Leu Val Ala Ala Thr Met Val Tyr Gly Thr Glu His Asn Ser 
                565                 570                 575     


Thr Phe Leu Glu Cys Leu Pro Lys Ser Pro Gln Ala Ala Val Arg Trp 
            580                 585                 590         


Leu Leu Gln Arg Pro Gly Asp Glu Gly Pro Asp Gln Val Lys Thr Asp 
        595                 600                 605             


Glu Arg Val Leu His Thr Glu Arg Gly Leu Leu Phe Arg Arg Leu Ser 
    610                 615                 620                 


Arg Phe Asp Ala Gly Thr Tyr Thr Cys Thr Thr Leu Glu His Gly Phe 
625                 630                 635                 640 


Ser Gln Thr Val Val Arg Leu Ala Leu Val Val Ile Val Ala Ser Gln 
                645                 650                 655     


Leu Asp Asn Leu Phe Pro Pro Glu Pro Lys Pro Glu Glu Pro Pro Ala 
            660                 665                 670         


Arg Gly Gly Leu Ala Ser Thr Pro Pro Lys Ala Trp Tyr Lys Asp Ile 
        675                 680                 685             


Leu Gln Leu Ile Gly Phe Ala Asn Leu Pro Arg Val Asp Glu Tyr Cys 
    690                 695                 700                 


Glu Arg Val Trp Cys Arg Gly Thr Thr Glu Cys Ser Gly Cys Phe Arg 
705                 710                 715                 720 


Ser Arg Ser Arg Gly Lys Gln Ala Arg Gly Lys Ser Trp Ala Gly Leu 
                725                 730                 735     


Glu Leu Gly Lys Lys Met Lys Ser Arg Val His Ala Glu His Asn Arg 
            740                 745                 750         


Thr Pro Arg Glu Val Glu Ala Thr 
        755                 760 


<210>  1179
<211>  651
<212>  PRT
<213>  Homo Sapiens

<400>  1179

Gly Gly Gly Gln Gly Pro Met Pro Arg Val Arg Tyr Tyr Ala Gly Asp 
1               5                   10                  15      


Glu Arg Arg Ala Leu Ser Phe Phe His Gln Lys Gly Leu Gln Asp Phe 
            20                  25                  30          


Asp Thr Leu Leu Leu Ser Gly Asp Gly Asn Thr Leu Tyr Val Gly Ala 
        35                  40                  45              


Arg Glu Ala Ile Leu Ala Leu Asp Ile Gln Asp Pro Gly Val Pro Arg 
    50                  55                  60                  


Leu Lys Asn Met Ile Pro Trp Pro Ala Ser Asp Arg Lys Lys Ser Glu 
65                  70                  75                  80  


Cys Ala Phe Lys Lys Lys Ser Asn Glu Thr Gln Cys Phe Asn Phe Ile 
                85                  90                  95      


Arg Val Leu Val Ser Tyr Asn Val Thr His Leu Tyr Thr Cys Gly Thr 
            100                 105                 110         


Phe Ala Phe Ser Pro Ala Cys Thr Phe Ile Glu Leu Gln Asp Ser Tyr 
        115                 120                 125             


Leu Leu Pro Ile Ser Glu Asp Lys Val Met Glu Gly Lys Gly Gln Ser 
    130                 135                 140                 


Pro Phe Asp Pro Ala His Lys His Thr Ala Val Leu Val Asp Gly Met 
145                 150                 155                 160 


Leu Tyr Ser Gly Thr Met Asn Asn Phe Leu Gly Ser Glu Pro Ile Leu 
                165                 170                 175     


Met Arg Thr Leu Gly Ser Gln Pro Val Leu Lys Thr Asp Asn Phe Leu 
            180                 185                 190         


Arg Trp Leu His His Asp Ala Ser Phe Val Ala Ala Ile Pro Ser Thr 
        195                 200                 205             


Gln Val Val Tyr Phe Phe Phe Glu Glu Thr Ala Ser Glu Phe Asp Phe 
    210                 215                 220                 


Phe Glu Arg Leu His Thr Ser Arg Val Ala Arg Val Cys Lys Asn Asp 
225                 230                 235                 240 


Val Gly Gly Glu Lys Leu Leu Gln Lys Lys Trp Thr Thr Phe Leu Lys 
                245                 250                 255     


Ala Gln Leu Leu Cys Thr Gln Pro Gly Gln Leu Pro Phe Asn Val Ile 
            260                 265                 270         


Arg His Ala Val Leu Leu Pro Ala Asp Ser Pro Thr Ala Pro His Ile 
        275                 280                 285             


Tyr Ala Val Phe Thr Ser Gln Trp Gln Val Gly Gly Thr Arg Ser Ser 
    290                 295                 300                 


Ala Val Cys Ala Phe Ser Leu Leu Asp Ile Glu Arg Val Phe Lys Gly 
305                 310                 315                 320 


Lys Tyr Lys Glu Leu Asn Lys Glu Thr Ser Arg Trp Thr Thr Tyr Arg 
                325                 330                 335     


Gly Pro Glu Thr Asn Pro Arg Pro Gly Ser Cys Ser Val Gly Pro Ser 
            340                 345                 350         


Ser Asp Lys Ala Leu Thr Phe Met Lys Asp His Phe Leu Met Asp Glu 
        355                 360                 365             


Gln Val Val Gly Thr Pro Leu Leu Val Lys Ser Gly Val Glu Tyr Thr 
    370                 375                 380                 


Arg Leu Ala Val Glu Thr Ala Gln Gly Leu Asp Gly His Ser His Leu 
385                 390                 395                 400 


Val Met Tyr Leu Gly Thr Thr Thr Gly Ser Leu His Lys Ala Val Val 
                405                 410                 415     


Ser Gly Asp Ser Ser Ala His Leu Val Glu Glu Ile Gln Leu Phe Pro 
            420                 425                 430         


Asp Pro Glu Pro Val Arg Asn Leu Gln Leu Ala Pro Thr Gln Gly Ala 
        435                 440                 445             


Val Phe Val Gly Phe Ser Gly Gly Val Trp Arg Val Pro Arg Ala Asn 
    450                 455                 460                 


Cys Ser Val Tyr Glu Ser Cys Val Asp Cys Val Leu Ala Arg Asp Pro 
465                 470                 475                 480 


His Cys Ala Trp Asp Pro Glu Ser Arg Thr Cys Cys Leu Leu Ser Ala 
                485                 490                 495     


Pro Asn Leu Asn Ser Trp Lys Gln Asp Met Glu Arg Gly Asn Pro Glu 
            500                 505                 510         


Trp Ala Cys Ala Ser Gly Pro Met Ser Arg Ser Leu Arg Pro Gln Ser 
        515                 520                 525             


Arg Pro Gln Ile Ile Lys Glu Val Leu Ala Val Pro Asn Ser Ile Leu 
    530                 535                 540                 


Glu Leu Pro Cys Pro His Leu Ser Ala Leu Ala Ser Tyr Tyr Trp Ser 
545                 550                 555                 560 


His Gly Pro Ala Ala Val Pro Glu Ala Ser Ser Thr Val Tyr Asn Gly 
                565                 570                 575     


Ser Leu Leu Leu Ile Val Gln Asp Gly Val Gly Gly Leu Tyr Gln Cys 
            580                 585                 590         


Trp Ala Thr Glu Asn Gly Phe Ser Tyr Pro Val Ile Ser Tyr Trp Val 
        595                 600                 605             


Asp Ser Gln Asp Gln Thr Leu Ala Leu Asp Pro Glu Leu Ala Gly Ile 
    610                 615                 620                 


Pro Arg Glu His Val Lys Val Pro Leu Thr Arg Val Ser Gly Gly Ala 
625                 630                 635                 640 


Ala Leu Ala Ala Gln Gln Ser Tyr Trp Pro His 
                645                 650     


<210>  1180
<211>  674
<212>  PRT
<213>  Homo Sapiens

<400>  1180

Leu Ser Pro Arg Ile Ser Leu Pro Leu Gly Ser Glu Glu Arg Pro Phe 
1               5                   10                  15      


Leu Arg Phe Glu Ala Glu His Ile Ser Asn Tyr Thr Ala Leu Leu Leu 
            20                  25                  30          


Ser Arg Asp Gly Arg Thr Leu Tyr Val Gly Ala Arg Glu Ala Leu Phe 
        35                  40                  45              


Ala Leu Ser Ser Asn Leu Ser Phe Leu Pro Gly Gly Glu Tyr Gln Glu 
    50                  55                  60                  


Leu Leu Trp Gly Ala Asp Ala Glu Lys Lys Gln Gln Cys Ser Phe Lys 
65                  70                  75                  80  


Gly Lys Asp Pro Gln Arg Asp Cys Gln Asn Tyr Ile Lys Ile Leu Leu 
                85                  90                  95      


Pro Leu Ser Gly Ser His Leu Phe Thr Cys Gly Thr Ala Ala Phe Ser 
            100                 105                 110         


Pro Met Cys Thr Tyr Ile Asn Met Glu Asn Phe Thr Leu Ala Arg Asp 
        115                 120                 125             


Glu Lys Gly Asn Val Leu Leu Glu Asp Gly Lys Gly Arg Cys Pro Phe 
    130                 135                 140                 


Asp Pro Asn Phe Lys Ser Thr Ala Leu Val Val Asp Gly Glu Leu Tyr 
145                 150                 155                 160 


Thr Gly Thr Val Ser Ser Phe Gln Gly Asn Asp Pro Ala Ile Ser Arg 
                165                 170                 175     


Ser Gln Ser Leu Arg Pro Thr Lys Thr Glu Ser Ser Leu Asn Trp Leu 
            180                 185                 190         


Gln Asp Pro Ala Phe Val Ala Ser Ala Tyr Ile Pro Glu Ser Leu Gly 
        195                 200                 205             


Ser Leu Gln Gly Asp Asp Asp Lys Ile Tyr Phe Phe Phe Ser Glu Thr 
    210                 215                 220                 


Gly Gln Glu Phe Glu Phe Phe Glu Asn Thr Ile Val Ser Arg Ile Ala 
225                 230                 235                 240 


Arg Ile Cys Lys Gly Asp Glu Gly Gly Glu Arg Val Leu Gln Gln Arg 
                245                 250                 255     


Trp Thr Ser Phe Leu Lys Ala Gln Leu Leu Cys Ser Arg Pro Asp Asp 
            260                 265                 270         


Gly Phe Pro Phe Asn Val Leu Gln Asp Val Phe Thr Leu Ser Pro Ser 
        275                 280                 285             


Pro Gln Asp Trp Arg Asp Thr Leu Phe Tyr Gly Val Phe Thr Ser Gln 
    290                 295                 300                 


Trp His Arg Gly Thr Thr Glu Gly Ser Ala Val Cys Val Phe Thr Met 
305                 310                 315                 320 


Lys Asp Val Gln Arg Val Phe Ser Gly Leu Tyr Lys Glu Val Asn Arg 
                325                 330                 335     


Glu Thr Gln Gln Trp Tyr Thr Val Thr His Pro Val Pro Thr Pro Arg 
            340                 345                 350         


Pro Gly Ala Cys Ile Thr Asn Ser Ala Arg Glu Arg Lys Ile Asn Ser 
        355                 360                 365             


Ser Leu Gln Leu Pro Asp Arg Val Leu Asn Phe Leu Lys Asp His Phe 
    370                 375                 380                 


Leu Met Asp Gly Gln Val Arg Ser Arg Met Leu Leu Leu Gln Pro Gln 
385                 390                 395                 400 


Ala Arg Tyr Gln Arg Val Ala Val His Arg Val Pro Gly Leu His His 
                405                 410                 415     


Thr Tyr Asp Val Leu Phe Leu Gly Thr Gly Asp Gly Arg Leu His Lys 
            420                 425                 430         


Ala Val Ser Val Gly Pro Arg Val His Ile Ile Glu Glu Leu Gln Ile 
        435                 440                 445             


Phe Ser Ser Gly Gln Pro Val Gln Asn Leu Leu Leu Asp Thr His Arg 
    450                 455                 460                 


Gly Leu Leu Tyr Ala Ala Ser His Ser Gly Val Val Gln Val Pro Met 
465                 470                 475                 480 


Ala Asn Cys Ser Leu Tyr Arg Ser Cys Gly Asp Cys Leu Leu Ala Arg 
                485                 490                 495     


Asp Pro Tyr Cys Ala Trp Ser Gly Ser Ser Cys Lys His Val Ser Leu 
            500                 505                 510         


Tyr Gln Pro Gln Leu Ala Thr Arg Pro Trp Ile Gln Asp Ile Glu Gly 
        515                 520                 525             


Ala Ser Ala Lys Asp Leu Cys Ser Ala Ser Ser Val Val Ser Pro Ser 
    530                 535                 540                 


Phe Val Pro Thr Gly Glu Lys Pro Cys Glu Gln Val Gln Phe Gln Pro 
545                 550                 555                 560 


Asn Thr Val Asn Thr Leu Ala Cys Pro Leu Leu Ser Asn Leu Ala Thr 
                565                 570                 575     


Arg Leu Trp Leu Arg Asn Gly Ala Pro Val Asn Ala Ser Ala Ser Cys 
            580                 585                 590         


His Val Leu Pro Thr Gly Asp Leu Leu Leu Val Gly Thr Gln Gln Leu 
        595                 600                 605             


Gly Glu Phe Gln Cys Trp Ser Leu Glu Glu Gly Phe Gln Gln Leu Val 
    610                 615                 620                 


Ala Ser Tyr Cys Pro Glu Val Val Glu Asp Gly Val Ala Asp Gln Thr 
625                 630                 635                 640 


Asp Glu Gly Gly Ser Val Pro Val Ile Ile Ser Thr Ser Arg Val Ser 
                645                 650                 655     


Ala Pro Ala Gly Gly Lys Ala Ser Trp Gly Ala Asp Arg Ser Tyr Trp 
            660                 665                 670         


Lys Glu 
        


<210>  1181
<211>  643
<212>  PRT
<213>  Homo Sapiens

<400>  1181

Ala Glu Val Trp Trp Asn Leu Val Pro Arg Lys Thr Val Ser Ser Gly 
1               5                   10                  15      


Glu Leu Ala Thr Val Val Arg Arg Phe Ser Gln Thr Gly Ile Gln Asp 
            20                  25                  30          


Phe Leu Thr Leu Thr Leu Thr Glu Pro Thr Gly Leu Leu Tyr Val Gly 
        35                  40                  45              


Ala Arg Glu Ala Leu Phe Ala Phe Ser Met Glu Ala Leu Glu Leu Gln 
    50                  55                  60                  


Gly Ala Ile Ser Trp Glu Ala Pro Val Glu Lys Lys Thr Glu Cys Ile 
65                  70                  75                  80  


Gln Lys Gly Lys Asn Asn Gln Thr Glu Cys Phe Asn Phe Ile Arg Phe 
                85                  90                  95      


Leu Gln Pro Tyr Asn Ala Ser His Leu Tyr Val Cys Gly Thr Tyr Ala 
            100                 105                 110         


Phe Gln Pro Lys Cys Thr Tyr Val Asn Met Leu Thr Phe Thr Leu Glu 
        115                 120                 125             


His Gly Glu Phe Glu Asp Gly Lys Gly Lys Cys Pro Tyr Asp Pro Ala 
    130                 135                 140                 


Lys Gly His Ala Gly Leu Leu Val Asp Gly Glu Leu Tyr Ser Ala Thr 
145                 150                 155                 160 


Leu Asn Asn Phe Leu Gly Thr Glu Pro Ile Ile Leu Arg Asn Met Gly 
                165                 170                 175     


Pro His His Ser Met Lys Thr Glu Tyr Leu Ala Phe Trp Leu Asn Glu 
            180                 185                 190         


Pro His Phe Val Gly Ser Ala Tyr Val Pro Glu Ser Val Gly Ser Phe 
        195                 200                 205             


Thr Gly Asp Asp Asp Lys Val Tyr Phe Phe Phe Arg Glu Arg Ala Val 
    210                 215                 220                 


Glu Ser Asp Cys Tyr Ala Glu Gln Val Val Ala Arg Val Ala Arg Val 
225                 230                 235                 240 


Cys Lys Gly Asp Met Gly Gly Ala Arg Thr Leu Gln Arg Lys Trp Thr 
                245                 250                 255     


Thr Phe Leu Lys Ala Arg Leu Ala Cys Ser Ala Pro Asn Trp Gln Leu 
            260                 265                 270         


Tyr Phe Asn Gln Leu Gln Ala Met His Thr Leu Gln Asp Thr Ser Trp 
        275                 280                 285             


His Asn Thr Thr Phe Phe Gly Val Phe Gln Ala Gln Trp Gly Asp Met 
    290                 295                 300                 


Tyr Leu Ser Ala Ile Cys Glu Tyr Gln Leu Glu Glu Ile Gln Arg Val 
305                 310                 315                 320 


Phe Glu Gly Pro Tyr Lys Glu Tyr His Glu Glu Ala Gln Lys Trp Asp 
                325                 330                 335     


Arg Tyr Thr Asp Pro Val Pro Ser Pro Arg Pro Gly Ser Cys Ile Asn 
            340                 345                 350         


Asn Trp His Arg Arg His Gly Tyr Thr Ser Ser Leu Glu Leu Pro Asp 
        355                 360                 365             


Asn Ile Leu Asn Phe Val Lys Lys His Pro Leu Met Glu Glu Gln Val 
    370                 375                 380                 


Gly Pro Arg Trp Ser Arg Pro Leu Leu Val Lys Lys Gly Thr Asn Phe 
385                 390                 395                 400 


Thr His Leu Val Ala Asp Arg Val Thr Gly Leu Asp Gly Ala Thr Tyr 
                405                 410                 415     


Thr Val Leu Phe Ile Gly Thr Gly Asp Gly Trp Leu Leu Lys Ala Val 
            420                 425                 430         


Ser Leu Gly Pro Trp Val His Leu Ile Glu Glu Leu Gln Leu Phe Asp 
        435                 440                 445             


Gln Glu Pro Met Arg Ser Leu Val Leu Ser Gln Ser Lys Lys Leu Leu 
    450                 455                 460                 


Phe Ala Gly Ser Arg Ser Gln Leu Val Gln Leu Pro Val Ala Asp Cys 
465                 470                 475                 480 


Met Lys Tyr Arg Ser Cys Ala Asp Cys Val Leu Ala Arg Asp Pro Tyr 
                485                 490                 495     


Cys Ala Trp Ser Val Asn Thr Ser Arg Cys Val Ala Val Gly Gly His 
            500                 505                 510         


Ser Gly Ser Leu Leu Ile Gln His Val Met Thr Ser Asp Thr Ser Gly 
        515                 520                 525             


Ile Cys Asn Leu Arg Gly Ser Lys Lys Val Arg Pro Thr Pro Lys Asn 
    530                 535                 540                 


Ile Thr Val Val Ala Gly Thr Asp Leu Val Leu Pro Cys His Leu Ser 
545                 550                 555                 560 


Ser Asn Leu Ala His Ala Arg Trp Thr Phe Gly Gly Arg Asp Leu Pro 
                565                 570                 575     


Ala Glu Gln Pro Gly Ser Phe Leu Tyr Asp Ala Arg Leu Gln Ala Leu 
            580                 585                 590         


Val Val Met Ala Ala Gln Pro Arg His Ala Gly Ala Tyr His Cys Phe 
        595                 600                 605             


Ser Glu Glu Gln Gly Ala Arg Leu Ala Ala Glu Gly Tyr Leu Val Ala 
    610                 615                 620                 


Val Val Ala Gly Pro Ser Val Thr Leu Glu Ala Arg Ala Pro Leu Glu 
625                 630                 635                 640 


Asn Leu Gly 
            


<210>  1182
<211>  713
<212>  PRT
<213>  Homo Sapiens

<400>  1182

Met Ala Phe Ala Pro Ile Pro Arg Ile Thr Trp Glu His Arg Glu Val 
1               5                   10                  15      


His Leu Val Gln Phe His Glu Pro Asp Ile Tyr Asn Tyr Ser Ala Leu 
            20                  25                  30          


Leu Leu Ser Glu Asp Lys Asp Thr Leu Tyr Ile Gly Ala Arg Glu Ala 
        35                  40                  45              


Val Phe Ala Val Asn Ala Leu Asn Ile Ser Glu Lys Gln His Glu Val 
    50                  55                  60                  


Tyr Trp Lys Val Ser Glu Asp Lys Lys Ala Lys Cys Ala Glu Lys Gly 
65                  70                  75                  80  


Lys Ser Lys Gln Thr Glu Cys Leu Asn Tyr Ile Arg Val Leu Gln Pro 
                85                  90                  95      


Leu Ser Ala Thr Ser Leu Tyr Val Cys Gly Thr Asn Ala Phe Gln Pro 
            100                 105                 110         


Ala Cys Asp His Leu Asn Leu Thr Ser Phe Lys Phe Leu Gly Lys Asn 
        115                 120                 125             


Glu Asp Gly Lys Gly Arg Cys Pro Phe Asp Pro Ala His Ser Tyr Thr 
    130                 135                 140                 


Ser Val Met Val Asp Gly Glu Leu Tyr Ser Gly Thr Ser Tyr Asn Phe 
145                 150                 155                 160 


Leu Gly Ser Glu Pro Ile Ile Ser Arg Asn Ser Ser His Ser Pro Leu 
                165                 170                 175     


Arg Thr Glu Tyr Ala Ile Pro Trp Leu Asn Glu Pro Ser Phe Val Phe 
            180                 185                 190         


Ala Asp Val Ile Arg Lys Ser Pro Asp Ser Pro Asp Gly Glu Asp Asp 
        195                 200                 205             


Arg Val Tyr Phe Phe Phe Thr Glu Val Ser Val Glu Tyr Glu Phe Val 
    210                 215                 220                 


Phe Arg Val Leu Ile Pro Arg Ile Ala Arg Val Cys Lys Gly Asp Gln 
225                 230                 235                 240 


Gly Gly Leu Arg Thr Leu Gln Lys Lys Trp Thr Ser Phe Leu Lys Ala 
                245                 250                 255     


Arg Leu Ile Cys Ser Arg Pro Asp Ser Gly Leu Val Phe Asn Val Leu 
            260                 265                 270         


Arg Asp Val Phe Val Leu Arg Ser Pro Gly Leu Lys Val Pro Val Phe 
        275                 280                 285             


Tyr Ala Leu Phe Thr Pro Gln Leu Asn Asn Val Gly Leu Ser Ala Val 
    290                 295                 300                 


Cys Ala Tyr Asn Leu Ser Thr Ala Glu Glu Val Phe Ser His Gly Lys 
305                 310                 315                 320 


Tyr Met Gln Ser Thr Thr Val Glu Gln Ser His Thr Lys Trp Val Arg 
                325                 330                 335     


Tyr Asn Gly Pro Val Pro Lys Pro Arg Pro Gly Ala Cys Ile Asp Ser 
            340                 345                 350         


Glu Ala Arg Ala Ala Asn Tyr Thr Ser Ser Leu Asn Leu Pro Asp Lys 
        355                 360                 365             


Thr Leu Gln Phe Val Lys Asp His Pro Leu Met Asp Asp Ser Val Thr 
    370                 375                 380                 


Pro Ile Asp Asn Arg Pro Arg Leu Ile Lys Lys Asp Val Asn Tyr Thr 
385                 390                 395                 400 


Gln Ile Val Val Asp Arg Thr Gln Ala Leu Asp Gly Thr Val Tyr Asp 
                405                 410                 415     


Val Met Phe Val Ser Thr Asp Arg Gly Ala Leu His Lys Ala Ile Ser 
            420                 425                 430         


Leu Glu His Ala Val His Ile Ile Glu Glu Thr Gln Leu Phe Gln Asp 
        435                 440                 445             


Phe Glu Pro Val Gln Thr Leu Leu Leu Ser Ser Lys Lys Gly Asn Arg 
    450                 455                 460                 


Phe Val Tyr Ala Gly Ser Asn Ser Gly Val Val Gln Ala Pro Leu Ala 
465                 470                 475                 480 


Phe Cys Gly Lys His Gly Thr Cys Glu Asp Cys Val Leu Ala Arg Asp 
                485                 490                 495     


Pro Tyr Cys Ala Trp Ser Pro Pro Thr Ala Thr Cys Val Ala Leu His 
            500                 505                 510         


Gln Thr Glu Ser Pro Ser Arg Gly Leu Ile Gln Glu Met Ser Gly Asp 
        515                 520                 525             


Ala Ser Val Cys Pro Asp Lys Ser Lys Gly Ser Tyr Arg Gln His Phe 
    530                 535                 540                 


Phe Lys His Gly Gly Thr Ala Glu Leu Lys Cys Ser Gln Lys Ser Asn 
545                 550                 555                 560 


Leu Ala Arg Val Phe Trp Lys Phe Gln Asn Asp Val Leu Lys Ala Glu 
                565                 570                 575     


Ser Pro Lys Tyr Gly Leu Met Gly Arg Lys Asn Leu Leu Ile Phe Asn 
            580                 585                 590         


Leu Ser Glu Gly Asp Ser Gly Val Tyr Gln Cys Leu Ser Glu Glu Arg 
        595                 600                 605             


Val Lys Asn Lys Thr Val Phe Gln Val Val Ala Lys His Val Leu Glu 
    610                 615                 620                 


Val Lys Val Val Pro Lys Pro Val Val Ala Pro Thr Leu Ser Val Val 
625                 630                 635                 640 


Gln Thr Glu Gly Ser Arg Ile Ala Thr Lys Val Leu Val Ala Ser Thr 
                645                 650                 655     


Gln Gly Ser Ser Pro Pro Thr Pro Ala Val Gln Ala Thr Ser Ser Gly 
            660                 665                 670         


Ala Ile Thr Leu Pro Pro Lys Pro Ala Pro Thr Gly Thr Ser Cys Glu 
        675                 680                 685             


Pro Lys Ile Val Ile Asn Thr Val Pro Gln Leu His Ser Glu Lys Thr 
    690                 695                 700                 


Met Tyr Leu Lys Ser Ser Asp Asn Arg 
705                 710             


<210>  1183
<211>  625
<212>  PRT
<213>  Homo Sapiens

<400>  1183

Arg Val Pro Arg Ser Val Pro Arg Thr Ser Leu Pro Ile Ser Glu Ala 
1               5                   10                  15      


Asp Ser Cys Leu Thr Arg Phe Ala Val Pro His Thr Tyr Asn Tyr Ser 
            20                  25                  30          


Val Leu Leu Val Asp Pro Ala Ser His Thr Leu Tyr Val Gly Ala Arg 
        35                  40                  45              


Asp Thr Ile Phe Ala Leu Ser Leu Pro Phe Ser Gly Glu Arg Pro Arg 
    50                  55                  60                  


Arg Ile Asp Trp Met Val Pro Glu Ala His Arg Gln Asn Cys Arg Lys 
65                  70                  75                  80  


Lys Gly Lys Lys Glu Asp Glu Cys His Asn Phe Val Gln Ile Leu Ala 
                85                  90                  95      


Ile Ala Asn Ala Ser His Leu Leu Thr Cys Gly Thr Phe Ala Phe Asp 
            100                 105                 110         


Pro Lys Cys Gly Val Ile Asp Val Ser Arg Phe Gln Gln Val Glu Arg 
        115                 120                 125             


Leu Glu Ser Gly Arg Gly Lys Cys Pro Phe Glu Pro Ala Gln Arg Ser 
    130                 135                 140                 


Ala Ala Val Met Ala Gly Gly Val Leu Tyr Ala Ala Thr Val Lys Asn 
145                 150                 155                 160 


Tyr Leu Gly Thr Glu Pro Ile Ile Thr Arg Ala Val Gly Arg Ala Glu 
                165                 170                 175     


Asp Trp Ile Arg Thr Asp Thr Leu Pro Ser Trp Leu Asn Ala Pro Ala 
            180                 185                 190         


Phe Val Ala Ala Val Ala Leu Ser Pro Ala Glu Trp Gly Asp Glu Asp 
        195                 200                 205             


Gly Asp Asp Glu Ile Tyr Phe Phe Phe Thr Glu Thr Ser Arg Ala Phe 
    210                 215                 220                 


Asp Ser Tyr Glu Arg Ile Lys Val Pro Arg Val Ala Arg Val Cys Ala 
225                 230                 235                 240 


Gly Asp Leu Gly Gly Arg Lys Thr Leu Gln Gln Arg Trp Thr Thr Phe 
                245                 250                 255     


Leu Lys Ala Asp Leu Leu Cys Pro Gly Pro Glu His Gly Arg Ala Ser 
            260                 265                 270         


Ser Val Leu Gln Asp Val Ala Val Leu Arg Pro Glu Leu Gly Ala Gly 
        275                 280                 285             


Thr Pro Ile Phe Tyr Gly Ile Phe Ser Ser Gln Trp Glu Gly Ala Thr 
    290                 295                 300                 


Ile Ser Ala Val Cys Ala Phe Arg Pro Gln Asp Ile Arg Thr Val Leu 
305                 310                 315                 320 


Asn Gly Pro Phe Arg Glu Leu Lys His Asp Cys Asn Arg Gly Leu Pro 
                325                 330                 335     


Val Val Asp Asn Asp Val Pro Gln Pro Arg Pro Gly Glu Cys Ile Thr 
            340                 345                 350         


Asn Asn Met Lys Leu Arg His Phe Gly Ser Ser Leu Ser Leu Pro Asp 
        355                 360                 365             


Arg Val Leu Thr Phe Ile Arg Asp His Pro Leu Met Asp Arg Pro Val 
    370                 375                 380                 


Phe Pro Ala Asp Gly His Pro Leu Leu Val Thr Thr Asp Thr Ala Tyr 
385                 390                 395                 400 


Leu Arg Val Val Ala His Arg Val Thr Ser Leu Ser Gly Lys Glu Tyr 
                405                 410                 415     


Asp Val Leu Tyr Leu Gly Thr Glu Asp Gly His Leu His Arg Ala Val 
            420                 425                 430         


Arg Ile Gly Ala Gln Leu Ser Val Leu Glu Asp Leu Ala Leu Phe Pro 
        435                 440                 445             


Glu Pro Gln Pro Val Glu Asn Met Lys Leu Tyr His Ser Trp Leu Leu 
    450                 455                 460                 


Val Gly Ser Arg Thr Glu Val Thr Gln Val Asn Thr Thr Asn Cys Gly 
465                 470                 475                 480 


Arg Leu Gln Ser Cys Ser Glu Cys Ile Leu Ala Gln Asp Pro Val Cys 
                485                 490                 495     


Ala Trp Ser Phe Arg Leu Asp Glu Cys Val Ala His Ala Gly Glu His 
            500                 505                 510         


Arg Gly Leu Val Gln Asp Ile Glu Ser Ala Asp Val Ser Ser Leu Cys 
        515                 520                 525             


Pro Lys Glu Pro Gly Glu Arg Pro Val Val Phe Glu Val Pro Val Ala 
    530                 535                 540                 


Thr Ala Ala His Val Val Leu Pro Cys Ser Pro Ser Ser Ala Trp Ala 
545                 550                 555                 560 


Ser Cys Val Trp His Gln Pro Ser Gly Val Thr Ala Leu Thr Pro Arg 
                565                 570                 575     


Arg Asp Gly Leu Glu Val Val Val Thr Pro Gly Ala Met Gly Ala Tyr 
            580                 585                 590         


Ala Cys Glu Cys Gln Glu Gly Gly Ala Ala His Val Val Ala Ala Tyr 
        595                 600                 605             


Ser Leu Val Trp Gly Ser Gln Arg Asp Ala Pro Ser Arg Ala His Thr 
    610                 615                 620                 


Val 
625 


<210>  1184
<211>  663
<212>  PRT
<213>  Homo Sapiens

<400>  1184

Val Pro Gly Pro Ser Leu Arg Arg Pro Ser Arg Glu Leu Asp Ala Thr 
1               5                   10                  15      


Pro Arg Met Thr Ile Pro Tyr Glu Glu Leu Ser Gly Thr Arg His Phe 
            20                  25                  30          


Lys Gly Gln Ala Gln Asn Tyr Ser Thr Leu Leu Leu Glu Glu Ala Ser 
        35                  40                  45              


Ala Arg Leu Leu Val Gly Ala Arg Gly Ala Leu Phe Ser Leu Ser Ala 
    50                  55                  60                  


Asn Asp Ile Gly Asp Gly Ala His Lys Glu Ile His Trp Glu Ala Ser 
65                  70                  75                  80  


Pro Glu Met Gln Ser Lys Cys His Gln Lys Gly Lys Asn Asn Gln Thr 
                85                  90                  95      


Glu Cys Phe Asn His Val Arg Phe Leu Gln Arg Leu Asn Ser Thr His 
            100                 105                 110         


Leu Tyr Ala Cys Gly Thr His Ala Phe Gln Pro Leu Cys Ala Ala Ile 
        115                 120                 125             


Asp Ala Glu Ala Phe Thr Leu Pro Thr Ser Phe Glu Glu Gly Lys Glu 
    130                 135                 140                 


Lys Cys Pro Tyr Asp Pro Ala Arg Gly Phe Thr Gly Leu Ile Ile Asp 
145                 150                 155                 160 


Gly Gly Leu Tyr Thr Ala Thr Arg Tyr Glu Phe Arg Ser Ile Pro Asp 
                165                 170                 175     


Ile Arg Arg Ser Arg His Pro His Ser Leu Arg Thr Glu Glu Thr Pro 
            180                 185                 190         


Met His Trp Leu Asn Asp Ala Glu Phe Val Phe Ser Val Leu Val Arg 
        195                 200                 205             


Glu Ser Lys Ala Ser Ala Val Gly Asp Asp Asp Lys Val Tyr Tyr Phe 
    210                 215                 220                 


Phe Thr Glu Arg Ala Thr Glu Glu Gly Ser Gly Ser Phe Thr Gln Ser 
225                 230                 235                 240 


Arg Ser Ser His Arg Val Ala Arg Val Ala Arg Val Cys Lys Gly Asp 
                245                 250                 255     


Leu Gly Gly Lys Lys Ile Leu Gln Lys Lys Trp Thr Ser Phe Leu Lys 
            260                 265                 270         


Ala Arg Leu Ile Cys His Ile Pro Leu Tyr Glu Thr Leu Arg Gly Val 
        275                 280                 285             


Cys Ser Leu Asp Ala Glu Thr Ser Ser Arg Thr His Phe Tyr Ala Ala 
    290                 295                 300                 


Phe Thr Leu Ser Thr Gln Trp Lys Thr Leu Glu Ala Ser Ala Ile Cys 
305                 310                 315                 320 


Arg Tyr Asp Leu Ala Glu Ile Gln Ala Val Phe Ala Gly Pro Tyr Met 
                325                 330                 335     


Glu Tyr Gln Asp Gly Ser Arg Arg Trp Gly Arg Tyr Glu Gly Gly Val 
            340                 345                 350         


Pro Glu Pro Arg Pro Gly Ser Cys Ile Thr Asp Ser Leu Arg Ser Gln 
        355                 360                 365             


Gly Tyr Asn Ser Ser Gln Asp Leu Pro Ser Leu Val Leu Asp Phe Val 
    370                 375                 380                 


Lys Leu His Pro Leu Met Ala Arg Pro Val Val Pro Thr Arg Gly Arg 
385                 390                 395                 400 


Pro Leu Leu Leu Lys Arg Asn Ile Arg Tyr Thr His Leu Thr Gly Thr 
                405                 410                 415     


Pro Val Thr Thr Pro Ala Gly Pro Thr Tyr Asp Leu Leu Phe Leu Gly 
            420                 425                 430         


Thr Ala Asp Gly Trp Ile His Lys Ala Val Val Leu Gly Ser Gly Met 
        435                 440                 445             


His Ile Ile Glu Glu Thr Gln Val Phe Arg Glu Ser Gln Ser Val Glu 
    450                 455                 460                 


Asn Leu Val Ile Ser Leu Leu Gln His Ser Leu Tyr Val Gly Ala Pro 
465                 470                 475                 480 


Ser Gly Val Ile Gln Leu Pro Leu Ser Ser Cys Ser Arg Tyr Arg Ser 
                485                 490                 495     


Cys Tyr Asp Cys Ile Leu Ala Arg Asp Pro Tyr Cys Gly Trp Asp Pro 
            500                 505                 510         


Gly Thr His Ala Cys Ala Ala Ala Thr Thr Ile Ala Asn Arg Ser Gln 
        515                 520                 525             


Gly Ser Arg Thr Ala Leu Ile Gln Asp Ile Glu Arg Gly Asn Arg Gly 
    530                 535                 540                 


Cys Glu Ser Ser Arg Asp Thr Gly Pro Pro Pro Pro Leu Lys Thr Arg 
545                 550                 555                 560 


Ser Val Leu Arg Gly Asp Asp Val Leu Leu Pro Cys Asp Gln Pro Ser 
                565                 570                 575     


Asn Leu Ala Arg Ala Leu Trp Leu Leu Asn Gly Ser Met Gly Leu Ser 
            580                 585                 590         


Asp Gly Gln Gly Gly Tyr Arg Val Gly Val Asp Gly Leu Leu Val Thr 
        595                 600                 605             


Asp Ala Gln Pro Glu His Ser Gly Asn Tyr Gly Cys Tyr Ala Glu Glu 
    610                 615                 620                 


Asn Gly Leu Arg Thr Leu Leu Ala Ser Tyr Ser Leu Thr Val Arg Pro 
625                 630                 635                 640 


Ala Thr Pro Ala Pro Ala Pro Lys Ala Pro Ala Thr Pro Gly Ala Gln 
                645                 650                 655     


Leu Ala Pro Asp Val Arg Leu 
            660             


<210>  1185
<211>  1036
<212>  PRT
<213>  Homo Sapiens

<400>  1185

Met Pro Cys Gly Phe Ser Pro Ser Pro Val Ala His His Leu Val Pro 
1               5                   10                  15      


Gly Pro Pro Asp Thr Pro Ala Gln Gln Leu Arg Cys Gly Trp Thr Val 
            20                  25                  30          


Gly Gly Trp Leu Leu Ser Leu Val Arg Gly Leu Leu Pro Cys Leu Pro 
        35                  40                  45              


Pro Gly Ala Arg Thr Ala Glu Gly Pro Ile Met Val Leu Ala Gly Pro 
    50                  55                  60                  


Leu Ala Val Ser Leu Leu Leu Pro Ser Leu Thr Leu Leu Val Ser His 
65                  70                  75                  80  


Leu Ser Ser Ser Gln Asp Val Ser Ser Glu Pro Ser Ser Glu Gln Gln 
                85                  90                  95      


Leu Cys Ala Leu Ser Lys His Pro Thr Val Ala Phe Glu Asp Leu Gln 
            100                 105                 110         


Pro Trp Val Ser Asn Phe Thr Tyr Pro Gly Ala Arg Asp Phe Ser Gln 
        115                 120                 125             


Leu Ala Leu Asp Pro Ser Gly Asn Gln Leu Ile Val Gly Ala Arg Asn 
    130                 135                 140                 


Tyr Leu Phe Arg Leu Ser Leu Ala Asn Val Ser Leu Leu Gln Ala Thr 
145                 150                 155                 160 


Glu Trp Ala Ser Ser Glu Asp Thr Arg Arg Ser Cys Gln Ser Lys Gly 
                165                 170                 175     


Lys Thr Glu Glu Glu Cys Gln Asn Tyr Val Arg Val Leu Ile Val Ala 
            180                 185                 190         


Gly Arg Lys Val Phe Met Cys Gly Thr Asn Ala Phe Ser Pro Met Cys 
        195                 200                 205             


Thr Ser Arg Gln Val Gly Asn Leu Ser Arg Thr Ile Glu Lys Ile Asn 
    210                 215                 220                 


Gly Val Ala Arg Cys Pro Tyr Asp Pro Arg His Asn Ser Thr Ala Val 
225                 230                 235                 240 


Ile Ser Ser Gln Gly Glu Leu Tyr Ala Ala Thr Val Ile Asp Phe Ser 
                245                 250                 255     


Gly Arg Asp Pro Ala Ile Tyr Arg Ser Leu Gly Ser Gly Pro Pro Leu 
            260                 265                 270         


Arg Thr Ala Gln Tyr Asn Ser Lys Trp Leu Asn Glu Pro Asn Phe Val 
        275                 280                 285             


Ala Ala Tyr Asp Ile Gly Leu Phe Ala Tyr Phe Phe Leu Arg Glu Asn 
    290                 295                 300                 


Ala Val Glu His Asp Cys Gly Arg Thr Val Tyr Ser Arg Val Ala Arg 
305                 310                 315                 320 


Val Cys Lys Asn Asp Val Gly Gly Arg Phe Leu Leu Glu Asp Thr Trp 
                325                 330                 335     


Thr Thr Phe Met Lys Ala Arg Leu Asn Cys Ser Arg Pro Gly Glu Val 
            340                 345                 350         


Pro Phe Tyr Tyr Asn Glu Leu Gln Ser Ala Phe His Leu Pro Glu Gln 
        355                 360                 365             


Asp Leu Ile Tyr Gly Val Phe Thr Thr Asn Val Asn Ser Ile Ala Ala 
    370                 375                 380                 


Ser Ala Val Cys Ala Phe Asn Leu Ser Ala Ile Ser Gln Ala Phe Asn 
385                 390                 395                 400 


Gly Pro Phe Arg Tyr Gln Glu Asn Pro Arg Ala Ala Trp Leu Pro Ile 
                405                 410                 415     


Ala Asn Pro Ile Pro Asn Phe Gln Cys Gly Thr Leu Pro Glu Thr Gly 
            420                 425                 430         


Pro Asn Glu Asn Leu Thr Glu Arg Ser Leu Gln Asp Ala Gln Arg Leu 
        435                 440                 445             


Phe Leu Met Ser Glu Ala Val Gln Pro Val Thr Pro Glu Pro Cys Val 
    450                 455                 460                 


Thr Gln Asp Ser Val Arg Phe Ser His Leu Val Val Asp Leu Val Gln 
465                 470                 475                 480 


Ala Lys Asp Thr Leu Tyr His Val Leu Tyr Ile Gly Thr Glu Ser Gly 
                485                 490                 495     


Thr Ile Leu Lys Ala Leu Ser Thr Ala Ser Arg Ser Leu His Gly Cys 
            500                 505                 510         


Tyr Leu Glu Glu Leu His Val Leu Pro Pro Gly Arg Arg Glu Pro Leu 
        515                 520                 525             


Arg Ser Leu Arg Ile Leu His Ser Ala Arg Ala Leu Phe Val Gly Leu 
    530                 535                 540                 


Arg Asp Gly Val Leu Arg Val Pro Leu Glu Arg Cys Ala Ala Tyr Arg 
545                 550                 555                 560 


Ser Gln Gly Ala Cys Leu Gly Ala Arg Asp Pro Tyr Cys Gly Trp Asp 
                565                 570                 575     


Gly Lys Gln Gln Arg Cys Ser Thr Leu Glu Asp Ser Ser Asn Met Ser 
            580                 585                 590         


Leu Trp Thr Gln Asn Ile Thr Ala Cys Pro Val Arg Asn Val Thr Arg 
        595                 600                 605             


Asp Gly Gly Phe Gly Pro Trp Ser Pro Trp Gln Pro Cys Glu His Leu 
    610                 615                 620                 


Asp Gly Asp Asn Ser Gly Ser Cys Leu Cys Arg Ala Arg Ser Cys Asp 
625                 630                 635                 640 


Ser Pro Arg Pro Arg Cys Gly Gly Leu Asp Cys Leu Gly Pro Ala Ile 
                645                 650                 655     


His Ile Ala Asn Cys Ser Arg Asn Gly Ala Trp Thr Pro Trp Ser Ser 
            660                 665                 670         


Trp Ala Leu Cys Ser Thr Ser Cys Gly Ile Gly Phe Gln Val Arg Gln 
        675                 680                 685             


Arg Ser Cys Ser Asn Pro Ala Pro Arg His Gly Gly Arg Ile Cys Val 
    690                 695                 700                 


Gly Lys Ser Arg Glu Glu Arg Phe Cys Asn Glu Asn Thr Pro Cys Pro 
705                 710                 715                 720 


Val Pro Ile Phe Trp Ala Ser Trp Gly Ser Trp Ser Lys Cys Ser Ser 
                725                 730                 735     


Asn Cys Gly Gly Gly Met Gln Ser Arg Arg Arg Ala Cys Glu Asn Gly 
            740                 745                 750         


Asn Ser Cys Leu Gly Cys Gly Val Glu Phe Lys Thr Cys Asn Pro Glu 
        755                 760                 765             


Gly Cys Pro Glu Val Arg Arg Asn Thr Pro Trp Thr Pro Trp Leu Pro 
    770                 775                 780                 


Val Asn Val Thr Gln Gly Gly Ala Arg Gln Glu Gln Arg Phe Arg Phe 
785                 790                 795                 800 


Thr Cys Arg Ala Pro Leu Ala Asp Pro His Gly Leu Gln Phe Gly Arg 
                805                 810                 815     


Arg Arg Thr Glu Thr Arg Thr Cys Pro Ala Asp Gly Ser Gly Ser Cys 
            820                 825                 830         


Asp Thr Asp Ala Leu Val Glu Asp Leu Leu Arg Ser Gly Ser Thr Ser 
        835                 840                 845             


Pro His Thr Val Ser Gly Gly Trp Ala Ala Trp Gly Pro Trp Ser Ser 
    850                 855                 860                 


Cys Ser Arg Asp Cys Glu Leu Gly Phe Arg Val Arg Lys Arg Thr Cys 
865                 870                 875                 880 


Thr Asn Pro Glu Pro Arg Asn Gly Gly Leu Pro Cys Val Gly Asp Ala 
                885                 890                 895     


Ala Glu Tyr Gln Asp Cys Asn Pro Gln Ala Cys Pro Val Arg Gly Ala 
            900                 905                 910         


Trp Ser Cys Trp Thr Ser Trp Ser Pro Cys Ser Ala Ser Cys Gly Gly 
        915                 920                 925             


Gly His Tyr Gln Arg Thr Arg Ser Cys Thr Ser Pro Ala Pro Ser Pro 
    930                 935                 940                 


Gly Glu Asp Ile Cys Leu Gly Leu His Thr Glu Glu Ala Leu Cys Ala 
945                 950                 955                 960 


Thr Gln Ala Cys Pro Glu Gly Trp Ser Pro Trp Ser Glu Trp Ser Lys 
                965                 970                 975     


Cys Thr Asp Asp Gly Ala Gln Ser Arg Ser Arg His Cys Glu Glu Leu 
            980                 985                 990         


Leu Pro Gly Ser Ser Ala Cys Ala  Gly Asn Ser Ser Gln  Ser Arg Pro 
        995                 1000                 1005             


Cys Pro  Tyr Ser Glu Ile Pro  Val Ile Leu Pro Ala  Ser Ser Met 
    1010                 1015                 1020             


Glu Glu  Ala Thr Gly Cys Ala  Gly Phe Asn Leu Ile  His 
    1025                 1030                 1035     


<210>  1186
<211>  631
<212>  PRT
<213>  Homo Sapiens

<400>  1186

Gly Phe Pro Glu Asp Ser Glu Pro Ile Ser Ile Ser His Gly Asn Tyr 
1               5                   10                  15      


Thr Lys Gln Tyr Pro Val Phe Val Gly His Lys Pro Gly Arg Asn Thr 
            20                  25                  30          


Thr Gln Arg His Arg Leu Asp Ile Gln Met Ile Met Ile Met Asn Gly 
        35                  40                  45              


Thr Leu Tyr Ile Ala Ala Arg Asp His Ile Tyr Thr Val Asp Ile Asp 
    50                  55                  60                  


Thr Ser His Thr Glu Glu Ile Tyr Cys Ser Lys Lys Leu Thr Trp Lys 
65                  70                  75                  80  


Ser Arg Gln Ala Asp Val Asp Thr Cys Arg Met Lys Gly Lys His Lys 
                85                  90                  95      


Asp Glu Cys His Asn Phe Ile Lys Val Leu Leu Lys Lys Asn Asp Asp 
            100                 105                 110         


Ala Leu Phe Val Cys Gly Thr Asn Ala Phe Asn Pro Ser Cys Arg Asn 
        115                 120                 125             


Tyr Lys Met Asp Thr Leu Glu Pro Phe Gly Asp Glu Phe Ser Gly Met 
    130                 135                 140                 


Ala Arg Cys Pro Tyr Asp Ala Lys His Ala Asn Val Ala Leu Phe Ala 
145                 150                 155                 160 


Asp Gly Lys Leu Tyr Ser Ala Thr Val Thr Asp Phe Leu Ala Ile Asp 
                165                 170                 175     


Ala Val Ile Tyr Arg Ser Leu Gly Glu Ser Pro Thr Leu Arg Thr Val 
            180                 185                 190         


Lys His Asp Ser Lys Trp Leu Lys Glu Pro Tyr Phe Val Gln Ala Val 
        195                 200                 205             


Asp Tyr Gly Asp Tyr Ile Tyr Phe Phe Phe Arg Glu Ile Ala Val Glu 
    210                 215                 220                 


Tyr Asn Thr Met Gly Lys Val Val Phe Pro Arg Val Ala Gln Val Cys 
225                 230                 235                 240 


Lys Asn Asp Met Gly Gly Ser Gln Arg Val Leu Glu Lys Gln Trp Thr 
                245                 250                 255     


Ser Phe Leu Lys Ala Arg Leu Asn Cys Ser Val Pro Gly Asp Ser His 
            260                 265                 270         


Phe Tyr Phe Asn Ile Leu Gln Ala Val Thr Asp Val Ile Arg Ile Asn 
        275                 280                 285             


Gly Arg Asp Val Val Leu Ala Thr Phe Ser Thr Pro Tyr Asn Ser Ile 
    290                 295                 300                 


Pro Gly Ser Ala Val Cys Ala Tyr Asp Met Leu Asp Ile Ala Ser Val 
305                 310                 315                 320 


Phe Thr Gly Arg Phe Lys Glu Gln Lys Ser Pro Asp Ser Thr Trp Thr 
                325                 330                 335     


Pro Val Pro Asp Glu Arg Val Pro Lys Pro Arg Pro Gly Cys Cys Ala 
            340                 345                 350         


Gly Ser Ser Ser Leu Glu Arg Tyr Ala Thr Ser Asn Glu Phe Pro Asp 
        355                 360                 365             


Asp Thr Leu Asn Phe Ile Lys Thr His Pro Leu Met Asp Glu Ala Val 
    370                 375                 380                 


Pro Ser Ile Phe Asn Arg Pro Trp Phe Leu Arg Thr Met Val Arg Tyr 
385                 390                 395                 400 


Arg Leu Thr Lys Ile Ala Val Asp Thr Ala Ala Gly Pro Tyr Gln Asn 
                405                 410                 415     


His Thr Val Val Phe Leu Gly Ser Glu Lys Gly Ile Ile Leu Lys Phe 
            420                 425                 430         


Leu Ala Arg Ile Gly Asn Ser Gly Phe Leu Asn Asp Ser Leu Phe Leu 
        435                 440                 445             


Glu Glu Met Ser Val Tyr Asn Ser Glu Lys Cys Ser Tyr Asp Gly Val 
    450                 455                 460                 


Glu Asp Lys Arg Ile Met Gly Met Gln Leu Asp Arg Ala Ser Ser Ser 
465                 470                 475                 480 


Leu Tyr Val Ala Phe Ser Thr Cys Val Ile Lys Val Pro Leu Gly Arg 
                485                 490                 495     


Cys Glu Arg His Gly Lys Cys Lys Lys Thr Cys Ile Ala Ser Arg Asp 
            500                 505                 510         


Pro Tyr Cys Gly Trp Ile Lys Glu Gly Gly Ala Cys Ser His Leu Ser 
        515                 520                 525             


Pro Asn Ser Arg Leu Thr Phe Glu Gln Asp Ile Glu Arg Gly Asn Thr 
    530                 535                 540                 


Asp Gly Leu Gly Asp Cys His Asn Ser Phe Val Ala Leu Asn Gly His 
545                 550                 555                 560 


Ser Ser Ser Leu Leu Pro Ser Thr Thr Thr Ser Asp Ser Thr Ala Gln 
                565                 570                 575     


Glu Gly Tyr Glu Ser Arg Gly Gly Met Leu Asp Trp Lys His Leu Leu 
            580                 585                 590         


Asp Ser Pro Asp Ser Thr Asp Pro Leu Gly Ala Val Ser Ser His Asn 
        595                 600                 605             


His Gln Asp Lys Lys Gly Val Ile Arg Glu Ser Tyr Leu Lys Gly His 
    610                 615                 620                 


Asp Gln Leu Val Pro Val Thr 
625                 630     


<210>  1187
<211>  578
<212>  PRT
<213>  Homo Sapiens

<400>  1187

Leu Phe Pro Glu Glu Pro Pro Pro Leu Ser Val Ala Pro Arg Asp Tyr 
1               5                   10                  15      


Leu Asn His Tyr Pro Val Phe Val Gly Ser Gly Pro Gly Arg Leu Thr 
            20                  25                  30          


Pro Ala Glu Gly Ala Asp Asp Leu Asn Ile Gln Arg Val Leu Arg Val 
        35                  40                  45              


Asn Arg Thr Leu Phe Ile Gly Asp Arg Asp Asn Leu Tyr Arg Val Glu 
    50                  55                  60                  


Leu Glu Pro Pro Thr Ser Thr Glu Leu Arg Tyr Gln Arg Lys Leu Thr 
65                  70                  75                  80  


Trp Arg Ser Asn Pro Ser Asp Ile Asn Val Cys Arg Met Lys Gly Lys 
                85                  90                  95      


Gln Glu Gly Glu Cys Arg Asn Phe Val Lys Val Leu Leu Leu Arg Asp 
            100                 105                 110         


Glu Ser Thr Leu Phe Val Cys Gly Ser Asn Ala Phe Asn Pro Val Cys 
        115                 120                 125             


Ala Asn Tyr Ser Ile Asp Thr Leu Gln Pro Val Gly Asp Asn Ile Ser 
    130                 135                 140                 


Gly Met Ala Arg Cys Pro Tyr Asp Pro Lys His Ala Asn Val Ala Leu 
145                 150                 155                 160 


Phe Ser Asp Gly Met Leu Phe Thr Ala Thr Val Thr Asp Phe Leu Ala 
                165                 170                 175     


Ile Asp Ala Val Ile Tyr Arg Ser Leu Gly Asp Arg Pro Thr Leu Arg 
            180                 185                 190         


Thr Val Lys His Asp Ser Lys Trp Phe Lys Glu Pro Tyr Phe Val His 
        195                 200                 205             


Ala Val Glu Trp Gly Ser His Val Tyr Phe Phe Phe Arg Glu Ile Ala 
    210                 215                 220                 


Met Glu Phe Asn Tyr Leu Glu Lys Val Val Val Ser Arg Val Ala Arg 
225                 230                 235                 240 


Val Cys Lys Asn Asp Val Gly Gly Ser Pro Arg Val Leu Glu Lys Gln 
                245                 250                 255     


Trp Thr Ser Phe Leu Lys Ala Arg Leu Asn Cys Ser Val Pro Gly Asp 
            260                 265                 270         


Ser His Phe Tyr Phe Asn Val Leu Gln Ala Val Thr Gly Val Val Ser 
        275                 280                 285             


Leu Gly Gly Arg Pro Val Val Leu Ala Val Phe Ser Thr Pro Ser Asn 
    290                 295                 300                 


Ser Ile Pro Gly Ser Ala Val Cys Ala Phe Asp Leu Thr Gln Val Ala 
305                 310                 315                 320 


Ala Val Phe Glu Gly Arg Phe Arg Glu Gln Lys Ser Pro Glu Ser Ile 
                325                 330                 335     


Trp Thr Pro Val Pro Glu Asp Gln Val Pro Arg Pro Arg Pro Gly Cys 
            340                 345                 350         


Cys Ala Ala Pro Gly Met Gln Tyr Asn Ala Ser Ser Ala Leu Pro Asp 
        355                 360                 365             


Asp Ile Leu Asn Phe Val Lys Thr His Pro Leu Met Asp Glu Ala Val 
    370                 375                 380                 


Pro Ser Leu Gly His Ala Pro Trp Ile Leu Arg Thr Leu Met Arg His 
385                 390                 395                 400 


Gln Leu Thr Arg Val Ala Val Asp Val Gly Ala Gly Pro Trp Gly Asn 
                405                 410                 415     


Gln Thr Val Val Phe Leu Gly Ser Glu Ala Gly Thr Val Leu Lys Phe 
            420                 425                 430         


Leu Val Arg Pro Asn Ala Ser Thr Ser Gly Thr Ser Gly Leu Ser Val 
        435                 440                 445             


Phe Leu Glu Glu Phe Glu Thr Tyr Arg Pro Asp Arg Cys Gly Arg Pro 
    450                 455                 460                 


Gly Gly Gly Glu Thr Gly Gln Arg Leu Leu Ser Leu Glu Leu Asp Ala 
465                 470                 475                 480 


Ala Ser Gly Gly Leu Leu Ala Ala Phe Pro Arg Cys Val Val Arg Val 
                485                 490                 495     


Pro Val Ala Arg Cys Gln Gln Tyr Ser Gly Cys Met Lys Asn Cys Ile 
            500                 505                 510         


Gly Ser Gln Asp Pro Tyr Cys Gly Trp Ala Pro Asp Gly Ser Cys Ile 
        515                 520                 525             


Phe Leu Ser Pro Gly Thr Arg Ala Ala Phe Glu Gln Asp Val Ser Gly 
    530                 535                 540                 


Ala Ser Thr Ser Gly Leu Gly Asp Cys Thr Gly Leu Leu Arg Ala Ser 
545                 550                 555                 560 


Leu Ser Glu Asp Arg Ala Gly Leu Val Ser Val Asn Leu Leu Val Thr 
                565                 570                 575     


Ser Ser 
        


<210>  1188
<211>  513
<212>  PRT
<213>  Homo Sapiens

<400>  1188

Ala Phe Pro Gln Asp Pro Leu Pro Leu Leu Ile Ser Asp Leu Gln Gly 
1               5                   10                  15      


Thr Ser Pro Leu Ser Trp Phe Arg Gly Leu Glu Asp Asp Ala Val Ala 
            20                  25                  30          


Ala Glu Leu Gly Leu Asp Phe Gln Arg Phe Leu Thr Leu Asn Arg Thr 
        35                  40                  45              


Leu Leu Val Ala Ala Arg Asp His Val Phe Ser Phe Asp Leu Gln Ala 
    50                  55                  60                  


Glu Glu Glu Gly Glu Gly Leu Val Pro Asn Lys Tyr Leu Thr Trp Arg 
65                  70                  75                  80  


Ser Gln Asp Val Glu Asn Cys Ala Val Arg Gly Lys Leu Thr Asp Glu 
                85                  90                  95      


Cys Tyr Asn Tyr Ile Arg Val Leu Val Pro Trp Asp Ser Gln Thr Leu 
            100                 105                 110         


Leu Ala Cys Gly Thr Asn Ser Phe Ser Pro Val Cys Arg Ser Tyr Gly 
        115                 120                 125             


Ile Thr Ser Leu Gln Gln Glu Gly Glu Glu Leu Ser Gly Gln Ala Arg 
    130                 135                 140                 


Cys Pro Phe Asp Ala Thr Gln Ser Asn Val Ala Ile Phe Ala Glu Gly 
145                 150                 155                 160 


Ser Leu Tyr Ser Ala Thr Ala Ala Asp Phe Gln Ala Ser Asp Ala Val 
                165                 170                 175     


Val Tyr Arg Ser Leu Gly Pro Gln Pro Pro Leu Arg Ser Ala Lys Tyr 
            180                 185                 190         


Asp Ser Lys Trp Leu Arg Glu Pro His Phe Val Gln Ala Leu Glu His 
        195                 200                 205             


Gly Asp His Val Tyr Phe Phe Phe Arg Glu Val Ser Val Glu Asp Ala 
    210                 215                 220                 


Arg Leu Gly Arg Val Gln Phe Ser Arg Val Ala Arg Val Cys Lys Arg 
225                 230                 235                 240 


Asp Met Gly Gly Ser Pro Arg Ala Leu Asp Arg His Trp Thr Ser Phe 
                245                 250                 255     


Leu Lys Leu Arg Leu Asn Cys Ser Val Pro Gly Asp Ser Thr Phe Tyr 
            260                 265                 270         


Phe Asp Val Leu Gln Ala Leu Thr Gly Pro Val Asn Leu His Gly Arg 
        275                 280                 285             


Ser Ala Leu Phe Gly Val Phe Thr Thr Gln Thr Asn Ser Ile Pro Gly 
    290                 295                 300                 


Ser Ala Val Cys Ala Phe Tyr Leu Asp Glu Ile Glu Arg Gly Phe Glu 
305                 310                 315                 320 


Gly Lys Phe Lys Glu Gln Arg Ser Leu Asp Gly Ala Trp Thr Pro Val 
                325                 330                 335     


Ser Glu Asp Arg Val Pro Ser Pro Arg Pro Gly Ser Cys Pro Ala His 
            340                 345                 350         


Ser Ser Pro Leu Gly Arg Ser Leu Gln Val Leu Arg Gly Ser Arg Glu 
        355                 360                 365             


Ala Pro Pro Val Pro Gly Pro Ala Arg Gly Leu Pro Gly Pro Arg Pro 
    370                 375                 380                 


Glu Lys Gly Gly Arg Arg Glu Ala Pro Val Val Pro Glu Ala Ser Pro 
385                 390                 395                 400 


Arg Arg Ala Leu Leu Pro Pro Gly Arg Pro Glu Arg Arg Pro Phe Gln 
                405                 410                 415     


Leu Leu Lys Gly Ala Val His Gly Leu Gln Arg Gly Glu Arg Pro Ser 
            420                 425                 430         


Pro Leu Gly His Glu Leu Asp Ala Leu Gln Asp Val Ser Pro Pro Pro 
        435                 440                 445             


Arg Pro Ala Pro Pro Ala Phe Pro Thr Arg Arg Val Ser Arg Gly Pro 
    450                 455                 460                 


Phe Ser Pro Arg Val Tyr Leu Leu Thr Val Phe Pro Pro Val Leu Asp 
465                 470                 475                 480 


Arg Arg Val Gly Gly Glu Lys Pro Val Ser Ser Val Ser Gln His Phe 
                485                 490                 495     


Arg Gly Ser Trp Arg Thr Pro Thr Pro Arg Ser Leu Pro Ala Lys Leu 
            500                 505                 510         


Pro 
    


<210>  1189
<211>  604
<212>  PRT
<213>  Homo Sapiens

<400>  1189

Gln Gly His Leu Arg Ser Gly Pro Arg Ile Phe Ala Val Trp Lys Gly 
1               5                   10                  15      


His Val Gly Gln Asp Arg Val Asp Phe Gly Gln Thr Glu Pro His Thr 
            20                  25                  30          


Val Leu Phe His Glu Pro Gly Ser Ser Ser Val Trp Val Gly Gly Arg 
        35                  40                  45              


Gly Lys Val Tyr Leu Phe Asp Phe Pro Glu Gly Lys Asn Ala Ser Val 
    50                  55                  60                  


Arg Thr Val Asn Ile Gly Ser Thr Lys Gly Ser Cys Leu Asp Lys Arg 
65                  70                  75                  80  


Asp Cys Glu Asn Tyr Ile Thr Leu Leu Glu Arg Arg Ser Glu Gly Leu 
                85                  90                  95      


Leu Ala Cys Gly Thr Asn Ala Arg His Pro Ser Cys Trp Asn Leu Val 
            100                 105                 110         


Asn Gly Thr Val Val Pro Leu Gly Glu Met Arg Gly Tyr Ala Pro Phe 
        115                 120                 125             


Ser Pro Asp Glu Asn Ser Leu Val Leu Phe Glu Gly Asp Glu Val Tyr 
    130                 135                 140                 


Ser Thr Ile Arg Lys Gln Glu Tyr Asn Gly Lys Ile Pro Arg Phe Arg 
145                 150                 155                 160 


Arg Ile Arg Gly Glu Ser Glu Leu Tyr Thr Ser Asp Thr Val Met Gln 
                165                 170                 175     


Asn Pro Gln Phe Ile Lys Ala Thr Ile Val His Gln Asp Gln Ala Tyr 
            180                 185                 190         


Asp Asp Lys Ile Tyr Tyr Phe Phe Arg Glu Asp Asn Pro Asp Lys Asn 
        195                 200                 205             


Pro Glu Ala Pro Leu Asn Val Ser Arg Val Ala Gln Leu Cys Arg Gly 
    210                 215                 220                 


Asp Gln Gly Gly Glu Ser Ser Leu Ser Val Ser Lys Trp Asn Thr Phe 
225                 230                 235                 240 


Leu Lys Ala Met Leu Val Cys Ser Asp Ala Ala Thr Asn Lys Asn Phe 
                245                 250                 255     


Asn Arg Leu Gln Asp Val Phe Leu Leu Pro Asp Pro Ser Gly Gln Trp 
            260                 265                 270         


Arg Asp Thr Arg Val Tyr Gly Val Phe Ser Asn Pro Trp Asn Tyr Ser 
        275                 280                 285             


Ala Val Cys Val Tyr Ser Leu Gly Asp Ile Asp Lys Val Phe Arg Thr 
    290                 295                 300                 


Ser Ser Leu Lys Gly Tyr His Ser Ser Leu Pro Asn Pro Arg Pro Gly 
305                 310                 315                 320 


Lys Cys Leu Pro Asp Gln Gln Pro Ile Pro Thr Glu Thr Phe Gln Val 
                325                 330                 335     


Ala Asp Arg His Pro Glu Val Ala Gln Arg Val Glu Pro Met Gly Pro 
            340                 345                 350         


Leu Lys Thr Pro Leu Phe His Ser Lys Tyr His Tyr Gln Lys Val Ala 
        355                 360                 365             


Val His Arg Met Gln Ala Ser His Gly Glu Thr Phe His Val Leu Tyr 
    370                 375                 380                 


Leu Thr Thr Asp Arg Gly Thr Ile His Lys Val Val Glu Pro Gly Glu 
385                 390                 395                 400 


Gln Glu His Ser Phe Ala Phe Asn Ile Met Glu Ile Gln Pro Phe Arg 
                405                 410                 415     


Arg Ala Ala Ala Ile Gln Thr Met Ser Leu Asp Ala Glu Arg Arg Lys 
            420                 425                 430         


Leu Tyr Val Ser Ser Gln Trp Glu Val Ser Gln Val Pro Leu Asp Leu 
        435                 440                 445             


Cys Glu Val Tyr Gly Gly Gly Cys His Gly Cys Leu Met Ser Arg Asp 
    450                 455                 460                 


Pro Tyr Cys Gly Trp Asp Gln Gly Arg Cys Ile Ser Ile Tyr Ser Ser 
465                 470                 475                 480 


Glu Arg Ser Val Leu Gln Ser Ile Asn Pro Ala Glu Pro His Lys Glu 
                485                 490                 495     


Cys Pro Asn Pro Lys Pro Asp Lys Ala Pro Leu Gln Lys Val Ser Leu 
            500                 505                 510         


Ala Pro Asn Ser Arg Tyr Tyr Leu Ser Cys Pro Met Glu Ser Arg His 
        515                 520                 525             


Ala Thr Tyr Ser Trp Arg His Lys Glu Asn Val Glu Gln Ser Cys Glu 
    530                 535                 540                 


Pro Gly His Gln Ser Pro Asn Cys Ile Leu Phe Ile Glu Asn Leu Thr 
545                 550                 555                 560 


Ala Gln Gln Tyr Gly His Tyr Phe Cys Glu Ala Gln Glu Gly Ser Tyr 
                565                 570                 575     


Phe Arg Glu Ala Gln His Trp Gln Leu Leu Pro Glu Asp Gly Ile Met 
            580                 585                 590         


Ala Glu His Leu Leu Gly His Ala Cys Ala Leu Ala 
        595                 600                 


<210>  1190
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  1190

Met Thr Val Gly Glu Lys Val Phe Ser Ser Asn Gly Gln Ser Ile Thr 
1               5                   10                  15      


Phe Asp Ala Ile Gln Glu Ala Cys Ala Arg Ala Gly Gly Arg Ile Ala 
            20                  25                  30          


Val Pro Arg Asn Pro Glu Glu Asn Glu Ala Ile Ala Ser Phe Val Lys 
        35                  40                  45              


Lys Tyr Asn Thr Tyr Ala Tyr Val Gly Leu Thr Glu Gly Pro Ser Pro 
    50                  55                  60                  


Gly Asp Phe Arg Tyr Ser Asp Gly Thr Pro Val Asn Tyr Thr Asn Trp 
65                  70                  75                  80  


Tyr Arg Gly Glu Pro Ala Gly Arg Gly Lys Glu Gln Cys Val Glu Met 
                85                  90                  95      


Tyr Thr Asp Gly Gln Trp Asn Asp Arg Asn Cys Leu Tyr Ser Arg Leu 
            100                 105                 110         


Thr Ile Cys Glu Phe 
        115         


<210>  1191
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  1191

Glu Val Lys Asp Val Cys Val Gly Ser Pro Gly Ile Pro Gly Thr Pro 
1               5                   10                  15      


Gly Ser His Gly Leu Pro Gly Arg Asp Gly Arg Asp Gly Val Lys Gly 
            20                  25                  30          


Asp Pro Gly Pro Pro Gly Pro Met Gly Pro Pro Gly Glu Thr Pro Cys 
        35                  40                  45              


Pro Pro Gly Asn Asn Gly Leu Pro Gly Ala Pro Gly Val Pro Gly Glu 
    50                  55                  60                  


Arg Gly Glu Lys Gly Glu Ala Gly Glu Arg Gly Pro Pro Gly Leu Pro 
65                  70                  75                  80  


Ala His Leu Asp Glu Glu Leu Gln Ala Thr Leu His Asp Phe Arg His 
                85                  90                  95      


Gln Ile Leu Gln Thr Arg Gly Ala Leu Ser Leu Gln Gly Ser Ile Met 
            100                 105                 110         


Thr Val Gly Glu Lys Val Phe Ser Ser Asn Gly Gln Ser Ile Thr Phe 
        115                 120                 125             


Asp Ala Ile Gln Glu Ala Cys Ala Arg Ala Gly Gly Arg Ile Ala Val 
    130                 135                 140                 


Pro Arg Asn Pro Glu Glu Asn Glu Ala Ile Ala Ser Phe Val Lys Lys 
145                 150                 155                 160 


Tyr Asn Thr Tyr Ala Tyr Val Gly Leu Thr Glu Gly Pro Ser Pro Gly 
                165                 170                 175     


Asp Phe Arg Tyr Ser Asp Gly Thr Pro Val Asn Tyr Thr Asn Trp Tyr 
            180                 185                 190         


Arg Gly Glu Pro Ala Gly Arg Gly Lys Glu Gln Cys Val Glu Met Tyr 
        195                 200                 205             


Thr Asp Gly Gln Trp Asn Asp Arg Asn Cys Leu Tyr Ser Arg Leu Thr 
    210                 215                 220                 


Ile Cys Glu Phe 
225             


<210>  1192
<211>  355
<212>  PRT
<213>  Homo Sapiens

<400>  1192

Ala Gly Met Lys Thr Tyr Ser His Arg Thr Met Pro Ser Ala Cys Thr 
1               5                   10                  15      


Leu Val Met Cys Ser Ser Val Glu Ser Gly Leu Pro Gly Arg Asp Gly 
            20                  25                  30          


Arg Asp Gly Arg Glu Gly Pro Arg Gly Glu Lys Gly Asp Pro Gly Leu 
        35                  40                  45              


Pro Gly Ala Ala Gly Gln Ala Gly Met Pro Gly Gln Ala Gly Pro Val 
    50                  55                  60                  


Gly Pro Lys Gly Asp Asn Gly Ser Val Gly Glu Pro Gly Pro Lys Gly 
65                  70                  75                  80  


Asp Thr Gly Pro Ser Gly Pro Pro Gly Pro Pro Gly Val Pro Gly Pro 
                85                  90                  95      


Ala Gly Arg Glu Gly Pro Leu Gly Lys Gln Gly Asn Ile Gly Pro Gln 
            100                 105                 110         


Gly Lys Pro Gly Pro Lys Gly Glu Ala Gly Pro Lys Gly Glu Val Gly 
        115                 120                 125             


Ala Pro Gly Met Gln Gly Ser Ala Gly Ala Arg Gly Leu Ala Gly Pro 
    130                 135                 140                 


Lys Gly Glu Arg Gly Val Pro Gly Glu Arg Gly Val Pro Gly Asn Thr 
145                 150                 155                 160 


Gly Ala Ala Gly Ser Ala Gly Ala Met Gly Pro Gln Gly Ser Pro Gly 
                165                 170                 175     


Ala Arg Gly Pro Pro Gly Leu Lys Gly Asp Lys Gly Ile Pro Gly Asp 
            180                 185                 190         


Lys Gly Ala Lys Gly Glu Ser Gly Leu Pro Asp Val Ala Ser Leu Arg 
        195                 200                 205             


Gln Gln Val Glu Ala Leu Gln Gly Gln Val Gln His Leu Gln Ala Ala 
    210                 215                 220                 


Phe Ser Gln Tyr Lys Lys Val Glu Leu Phe Pro Asn Gly Gln Ser Val 
225                 230                 235                 240 


Gly Glu Lys Ile Phe Lys Thr Ala Gly Phe Val Lys Pro Phe Thr Glu 
                245                 250                 255     


Ala Gln Leu Leu Cys Thr Gln Ala Gly Gly Gln Leu Ala Ser Pro Arg 
            260                 265                 270         


Ser Ala Ala Glu Asn Ala Ala Leu Gln Gln Leu Val Val Ala Lys Asn 
        275                 280                 285             


Glu Ala Ala Phe Leu Ser Met Thr Asp Ser Lys Thr Glu Gly Lys Phe 
    290                 295                 300                 


Thr Tyr Pro Thr Gly Glu Ser Leu Val Tyr Ser Asn Trp Ala Pro Gly 
305                 310                 315                 320 


Lys Pro Asn Asp Asp Gly Gly Ser Glu Asp Cys Val Glu Ile Phe Thr 
                325                 330                 335     


Asn Gly Lys Trp Asn Asp Arg Ala Cys Gly Glu Lys Arg Leu Val Val 
            340                 345                 350         


Cys Glu Phe 
        355 


<210>  1193
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  1193

Met Pro Gly Val Cys Asp Arg Ala Pro Asp Phe Leu Ser Pro Ser Glu 
1               5                   10                  15      


Asp Gln Val Leu Arg Pro Ala Leu Gly Ser Ser Val Ala Leu Asn Cys 
            20                  25                  30          


Thr Ala Trp Val Val Ser Gly Pro His Cys Ser Leu Pro Ser Val Gln 
        35                  40                  45              


Trp Leu Lys Asp Gly Leu Pro Leu Gly Ile Gly Gly His Tyr Ser Leu 
    50                  55                  60                  


His Glu Tyr Ser Trp Val Lys Ala Asn Leu Ser Glu Val Leu Val Ser 
65                  70                  75                  80  


Ser Val Leu Gly Val Asn Val Thr Ser Thr Glu Val Tyr Gly Ala Phe 
                85                  90                  95      


Thr Cys Ser Ile Gln Asn Ile Ser Phe Ser Ser Phe Thr Leu Gln Arg 
            100                 105                 110         


Ala Gly Pro Thr Ser His 
        115             


<210>  1194
<211>  534
<212>  PRT
<213>  Homo Sapiens

<400>  1194

Met Asp Gly Arg Phe Trp Ile Arg Val Gln Glu Ser Val Met Val Pro 
1               5                   10                  15      


Glu Gly Leu Cys Ile Ser Val Pro Cys Ser Phe Ser Tyr Pro Arg Gln 
            20                  25                  30          


Asp Trp Thr Gly Ser Thr Pro Ala Tyr Gly Tyr Trp Phe Lys Ala Val 
        35                  40                  45              


Thr Glu Thr Thr Lys Gly Ala Pro Val Ala Thr Asn His Gln Ser Arg 
    50                  55                  60                  


Glu Val Glu Met Ser Thr Arg Gly Arg Phe Gln Leu Thr Gly Asp Pro 
65                  70                  75                  80  


Ala Lys Gly Asn Cys Ser Leu Val Ile Arg Asp Ala Gln Met Gln Asp 
                85                  90                  95      


Glu Ser Gln Tyr Phe Phe Arg Val Glu Arg Gly Ser Tyr Val Arg Tyr 
            100                 105                 110         


Asn Phe Met Asn Asp Gly Phe Phe Leu Lys Val Thr Ala Leu Thr Gln 
        115                 120                 125             


Lys Pro Asp Val Tyr Ile Pro Glu Thr Leu Glu Pro Gly Gln Pro Val 
    130                 135                 140                 


Thr Val Ile Cys Val Phe Asn Trp Ala Phe Glu Glu Cys Pro Pro Pro 
145                 150                 155                 160 


Ser Phe Ser Trp Thr Gly Ala Ala Leu Ser Ser Gln Gly Thr Lys Pro 
                165                 170                 175     


Thr Thr Ser His Phe Ser Val Leu Ser Phe Thr Pro Arg Pro Gln Asp 
            180                 185                 190         


His Asn Thr Asp Leu Thr Cys His Val Asp Phe Ser Arg Lys Gly Val 
        195                 200                 205             


Ser Val Gln Arg Thr Val Arg Leu Arg Val Ala Tyr Ala Pro Arg Asp 
    210                 215                 220                 


Leu Val Ile Ser Ile Ser Arg Asp Asn Thr Pro Ala Leu Glu Pro Gln 
225                 230                 235                 240 


Pro Gln Gly Asn Val Pro Tyr Leu Glu Ala Gln Lys Gly Gln Phe Leu 
                245                 250                 255     


Arg Leu Leu Cys Ala Ala Asp Ser Gln Pro Pro Ala Thr Leu Ser Trp 
            260                 265                 270         


Val Leu Gln Asn Arg Val Leu Ser Ser Ser His Pro Trp Gly Pro Arg 
        275                 280                 285             


Pro Leu Gly Leu Glu Leu Pro Gly Val Lys Ala Gly Asp Ser Gly Arg 
    290                 295                 300                 


Tyr Thr Cys Arg Ala Glu Asn Arg Leu Gly Ser Gln Gln Arg Ala Leu 
305                 310                 315                 320 


Asp Leu Ser Val Gln Tyr Pro Pro Glu Asn Leu Arg Val Met Val Ser 
                325                 330                 335     


Gln Ala Asn Arg Thr Val Leu Glu Asn Leu Gly Asn Gly Thr Ser Leu 
            340                 345                 350         


Pro Val Leu Glu Gly Gln Ser Leu Cys Leu Val Cys Val Thr His Ser 
        355                 360                 365             


Ser Pro Pro Ala Arg Leu Ser Trp Thr Gln Arg Gly Gln Val Leu Ser 
    370                 375                 380                 


Pro Ser Gln Pro Ser Asp Pro Gly Val Leu Glu Leu Pro Arg Val Gln 
385                 390                 395                 400 


Val Glu His Glu Gly Glu Phe Thr Cys His Ala Arg His Pro Leu Gly 
                405                 410                 415     


Ser Gln His Val Ser Leu Ser Leu Ser Val His Tyr Ser Pro Lys Leu 
            420                 425                 430         


Leu Gly Pro Ser Cys Ser Trp Glu Ala Glu Gly Leu His Cys Ser Cys 
        435                 440                 445             


Ser Ser Gln Ala Ser Pro Ala Pro Ser Leu Arg Trp Trp Leu Gly Glu 
    450                 455                 460                 


Glu Leu Leu Glu Gly Asn Ser Ser Gln Asp Ser Phe Glu Val Thr Pro 
465                 470                 475                 480 


Ser Ser Ala Gly Pro Trp Ala Asn Ser Ser Leu Ser Leu His Gly Gly 
                485                 490                 495     


Leu Ser Ser Gly Leu Arg Leu Arg Cys Glu Ala Trp Asn Val His Gly 
            500                 505                 510         


Ala Gln Ser Gly Ser Ile Leu Gln Leu Pro Asp Lys Lys Gly Leu Ile 
        515                 520                 525             


Ser Thr Ala Phe Ser Asn 
    530                 


<210>  1195
<211>  534
<212>  PRT
<213>  Homo Sapiens

<400>  1195

Leu Asn Lys Asp Pro Ser Tyr Ser Leu Gln Val Gln Arg Gln Val Pro 
1               5                   10                  15      


Val Pro Glu Gly Leu Cys Val Ile Val Ser Cys Asn Leu Ser Tyr Pro 
            20                  25                  30          


Arg Asp Gly Trp Asp Glu Ser Thr Ala Ala Tyr Gly Tyr Trp Phe Lys 
        35                  40                  45              


Gly Arg Thr Ser Pro Lys Thr Gly Ala Pro Val Ala Thr Asn Asn Gln 
    50                  55                  60                  


Ser Arg Glu Val Glu Met Ser Thr Arg Asp Arg Phe Gln Leu Thr Gly 
65                  70                  75                  80  


Asp Pro Gly Lys Gly Ser Cys Ser Leu Val Ile Arg Asp Ala Gln Arg 
                85                  90                  95      


Glu Asp Glu Ala Trp Tyr Phe Phe Arg Val Glu Arg Gly Ser Arg Val 
            100                 105                 110         


Arg His Ser Phe Leu Ser Asn Ala Phe Phe Leu Lys Val Thr Ala Leu 
        115                 120                 125             


Thr Lys Lys Pro Asp Val Tyr Ile Pro Glu Thr Leu Glu Pro Gly Gln 
    130                 135                 140                 


Pro Val Thr Val Ile Cys Val Phe Asn Trp Ala Phe Lys Lys Cys Pro 
145                 150                 155                 160 


Ala Pro Ser Phe Ser Trp Thr Gly Ala Ala Leu Ser Pro Arg Arg Thr 
                165                 170                 175     


Arg Pro Ser Thr Ser His Phe Ser Val Leu Ser Phe Thr Pro Ser Pro 
            180                 185                 190         


Gln Asp His Asp Thr Asp Leu Thr Cys His Val Asp Phe Ser Arg Lys 
        195                 200                 205             


Gly Val Ser Ala Gln Arg Thr Val Arg Leu Arg Val Ala Tyr Ala Pro 
    210                 215                 220                 


Lys Asp Leu Ile Ile Ser Ile Ser His Asp Asn Thr Ser Ala Leu Glu 
225                 230                 235                 240 


Leu Gln Gly Asn Val Ile Tyr Leu Glu Val Gln Lys Gly Gln Phe Leu 
                245                 250                 255     


Arg Leu Leu Cys Ala Ala Asp Ser Gln Pro Pro Ala Thr Leu Ser Trp 
            260                 265                 270         


Val Leu Gln Asp Arg Val Leu Ser Ser Ser His Pro Trp Gly Pro Arg 
        275                 280                 285             


Thr Leu Gly Leu Glu Leu Arg Gly Val Arg Ala Gly Asp Ser Gly Arg 
    290                 295                 300                 


Tyr Thr Cys Arg Ala Glu Asn Arg Leu Gly Ser Gln Gln Gln Ala Leu 
305                 310                 315                 320 


Asp Leu Ser Val Gln Tyr Pro Pro Glu Asn Leu Arg Val Met Val Ser 
                325                 330                 335     


Gln Ala Asn Arg Thr Val Leu Glu Asn Leu Gly Asn Gly Thr Ser Leu 
            340                 345                 350         


Pro Val Leu Glu Gly Gln Ser Leu Arg Leu Val Cys Val Thr His Ser 
        355                 360                 365             


Ser Pro Pro Ala Arg Leu Ser Trp Thr Arg Trp Gly Gln Thr Val Gly 
    370                 375                 380                 


Pro Ser Gln Pro Ser Asp Pro Gly Val Leu Glu Leu Pro Pro Ile Gln 
385                 390                 395                 400 


Met Glu His Glu Gly Glu Phe Thr Cys His Ala Gln His Pro Leu Gly 
                405                 410                 415     


Ser Gln His Val Ser Leu Ser Leu Ser Val His Tyr Pro Pro Gln Leu 
            420                 425                 430         


Leu Gly Pro Ser Cys Ser Trp Glu Ala Glu Gly Leu His Cys Ser Cys 
        435                 440                 445             


Ser Ser Gln Ala Ser Pro Ala Pro Ser Leu Arg Trp Trp Leu Gly Glu 
    450                 455                 460                 


Glu Leu Leu Glu Gly Asn Ser Ser Gln Gly Ser Phe Glu Val Thr Pro 
465                 470                 475                 480 


Ser Ser Ala Gly Pro Trp Ala Asn Ser Ser Leu Ser Leu His Gly Gly 
                485                 490                 495     


Leu Ser Ser Gly Leu Arg Leu Arg Cys Lys Ala Trp Asn Val His Gly 
            500                 505                 510         


Ala Gln Ser Gly Ser Val Phe Gln Leu Leu Pro Gly Lys Leu Glu His 
        515                 520                 525             


Gly Gly Gly Leu Gly Leu 
    530                 


<210>  1196
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  1196

Lys Glu Gln Lys Asp Tyr Leu Leu Thr Met Gln Lys Ser Val Thr Val 
1               5                   10                  15      


Gln Glu Gly Leu Cys Val Ser Val Leu Cys Ser Phe Ser Tyr Pro Gln 
            20                  25                  30          


Asn Gly Trp Thr Ala Ser Asp Pro Val His Gly Tyr Trp Phe Arg Ala 
        35                  40                  45              


Gly Asp His Val Ser Arg Asn Ile Pro Val Ala Thr Asn Asn Pro Ala 
    50                  55                  60                  


Arg Ala Val Gln Glu Glu Thr Arg Asp Arg Phe His Leu Leu Gly Asp 
65                  70                  75                  80  


Pro Gln Asn Lys Asp Cys Thr Leu Ser Ile Arg Asp Thr Arg Glu Ser 
                85                  90                  95      


Asp Ala Gly Thr Tyr Val Phe Cys Val Glu Arg Gly Asn Met Lys Trp 
            100                 105                 110         


Asn Tyr Lys Tyr Asp Gln Leu Ser Val Asn Val Thr Ala Ser Gln Asp 
        115                 120                 125             


Leu Leu Ser Arg Tyr Arg Leu Glu Val Pro Glu Ser Val Thr Val Gln 
    130                 135                 140                 


Glu Gly Leu Cys Val Ser Val Pro Cys Ser Val Leu Tyr Pro His Tyr 
145                 150                 155                 160 


Asn Trp Thr Ala Ser Ser Pro Val Tyr Gly Ser Trp Phe Lys Glu Gly 
                165                 170                 175     


Ala Asp Ile Pro Trp Asp Ile Pro Val Ala Thr Asn Thr Pro Ser Gly 
            180                 185                 190         


Lys Val Gln Glu Asp Thr His Gly Arg Phe Leu Leu Leu Gly Asp Pro 
        195                 200                 205             


Gln Thr Asn Asn Cys Ser Leu Ser Ile Arg Asp Ala Arg Lys Gly Asp 
    210                 215                 220                 


Ser Gly Lys Tyr Tyr Phe Gln Val Glu Arg Gly Ser Arg Lys Trp Asn 
225                 230                 235                 240 


Tyr Ile Tyr Asp Lys Leu Ser Val His Val Thr Ala Leu Thr His Met 
                245                 250                 255     


Pro Thr Phe Ser Ile Pro Gly Thr Leu Glu Ser Gly His Pro Arg Asn 
            260                 265                 270         


Leu Thr Cys Ser Val Pro Trp Ala Cys Glu Gln Gly Thr Pro Pro Thr 
        275                 280                 285             


Ile Thr Trp Met Gly Ala Ser Val Ser Ser Leu Asp Pro Thr Ile Thr 
    290                 295                 300                 


Arg Ser Ser Met Leu Ser Leu Ile Pro Gln Pro Gln Asp His Gly Thr 
305                 310                 315                 320 


Ser Leu Thr Cys Gln Val Thr Leu Pro Gly Ala Gly Val Thr Met Thr 
                325                 330                 335     


Arg Ala Val Arg Leu Asn Ile Ser Tyr Pro Pro Gln Asn Leu Thr Met 
            340                 345                 350         


Thr Val Phe Gln Gly Asp Gly Thr Ala Ser Thr Thr Leu Arg Asn Gly 
        355                 360                 365             


Ser Ala Leu Ser Val Leu Glu Gly Gln Ser Leu His Leu Val Cys Ala 
    370                 375                 380                 


Val Asp Ser Asn Pro Pro Ala Arg Leu Ser Trp Thr Trp Gly Ser Leu 
385                 390                 395                 400 


Thr Leu Ser Pro Ser Gln Ser Ser Asn Leu Gly Val Leu Glu Leu Pro 
                405                 410                 415     


Arg Val His Val Lys Asp Glu Gly Glu Phe Thr Cys Arg Ala Gln Asn 
            420                 425                 430         


Pro Leu Gly Ser Gln His Ile Ser Leu Ser Leu Ser Leu Gln Asn Glu 
        435                 440                 445             


Tyr Thr Gly Lys Met Arg Pro Ile Ser Gly Val Thr Leu Gly Ala 
    450                 455                 460             


<210>  1197
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  1197

Glu Lys Pro Val Tyr Glu Leu Gln Val Gln Lys Ser Val Thr Val Gln 
1               5                   10                  15      


Glu Gly Leu Cys Val Leu Val Pro Cys Ser Phe Ser Tyr Pro Trp Arg 
            20                  25                  30          


Ser Trp Tyr Ser Ser Pro Pro Leu Tyr Val Tyr Trp Phe Arg Asp Gly 
        35                  40                  45              


Glu Ile Pro Tyr Tyr Ala Glu Val Val Ala Thr Asn Asn Pro Asp Arg 
    50                  55                  60                  


Arg Val Lys Pro Glu Thr Gln Gly Arg Phe Arg Leu Leu Gly Asp Val 
65                  70                  75                  80  


Gln Lys Lys Asn Cys Ser Leu Ser Ile Gly Asp Ala Arg Met Glu Asp 
                85                  90                  95      


Thr Gly Ser Tyr Phe Phe Arg Val Glu Arg Gly Arg Asp Val Lys Tyr 
            100                 105                 110         


Ser Tyr Gln Gln Asn Lys Leu Asn Leu Glu Val Thr Ala Leu Ile Glu 
        115                 120                 125             


Lys Pro Asp Ile His Phe Leu Glu Pro Leu Glu Ser Gly Arg Pro Thr 
    130                 135                 140                 


Arg Leu Ser Cys Ser Leu Pro Gly Ser Cys Glu Ala Gly Pro Pro Leu 
145                 150                 155                 160 


Thr Phe Ser Trp Thr Gly Asn Ala Leu Ser Pro Leu Asp Pro Glu Thr 
                165                 170                 175     


Thr Arg Ser Ser Glu Leu Thr Leu Thr Pro Arg Pro Glu Asp His Gly 
            180                 185                 190         


Thr Asn Leu Thr Cys Gln Val Lys Arg Gln Gly Ala Gln Val Thr Thr 
        195                 200                 205             


Glu Arg Thr Val Gln Leu Asn Val Ser Tyr Ala Pro Gln Asn Leu Ala 
    210                 215                 220                 


Ile Ser Ile Phe Phe Arg Asn Gly Thr Gly Thr Ala Leu Arg Ile Leu 
225                 230                 235                 240 


Ser Asn Gly Met Ser Val Pro Ile Gln Glu Gly Gln Ser Leu Phe Leu 
                245                 250                 255     


Ala Cys Thr Val Asp Ser Asn Pro Pro Ala Ser Leu Ser Trp Phe Arg 
            260                 265                 270         


Glu Gly Lys Ala Leu Asn Pro Ser Gln Thr Ser Met Ser Gly Thr Leu 
        275                 280                 285             


Glu Leu Pro Asn Ile Gly Ala Arg Glu Gly Gly Glu Phe Thr Cys Arg 
    290                 295                 300                 


Val Gln His Pro Leu Gly Ser Gln His Leu Ser Phe Ile Leu Ser Val 
305                 310                 315                 320 


Gln Arg Ser Ser Ser Ser Cys Ile Cys Val Thr Glu Lys Gln Gln Gly 
                325                 330                 335     


Ser Trp Pro Leu Val Leu 
            340         


<210>  1198
<211>  244
<212>  PRT
<213>  Homo Sapiens

<400>  1198

Phe Val Arg Thr Lys Ile Asp Thr Thr Glu Asn Leu Leu Asn Thr Glu 
1               5                   10                  15      


Val His Ser Ser Pro Ala Gln Arg Trp Ser Met Gln Val Pro Pro Glu 
            20                  25                  30          


Val Ser Ala Glu Ala Gly Asp Ala Ala Val Leu Pro Cys Thr Phe Thr 
        35                  40                  45              


His Pro His Arg His Tyr Asp Gly Pro Leu Thr Ala Ile Trp Arg Ala 
    50                  55                  60                  


Gly Glu Pro Tyr Ala Gly Pro Gln Val Phe Arg Cys Ala Ala Ala Arg 
65                  70                  75                  80  


Gly Ser Glu Leu Cys Gln Thr Ala Leu Ser Leu His Gly Arg Phe Arg 
                85                  90                  95      


Leu Leu Gly Asn Pro Arg Arg Asn Asp Leu Ser Leu Arg Val Glu Arg 
            100                 105                 110         


Leu Ala Leu Ala Asp Asp Arg Arg Tyr Phe Cys Arg Val Glu Phe Ala 
        115                 120                 125             


Gly Asp Val His Asp Arg Tyr Glu Ser Arg His Gly Val Arg Leu His 
    130                 135                 140                 


Val Thr Ala Ala Pro Arg Ile Val Asn Ile Ser Val Leu Pro Ser Pro 
145                 150                 155                 160 


Ala His Ala Phe Arg Ala Leu Cys Thr Ala Glu Gly Glu Pro Pro Pro 
                165                 170                 175     


Ala Leu Ala Trp Ser Gly Pro Ala Leu Gly Asn Ser Leu Ala Ala Val 
            180                 185                 190         


Arg Ser Pro Arg Glu Gly His Gly His Leu Val Thr Ala Glu Leu Pro 
        195                 200                 205             


Ala Leu Thr His Asp Gly Arg Tyr Thr Cys Thr Ala Ala Asn Ser Leu 
    210                 215                 220                 


Gly Arg Ser Glu Ala Ser Val Tyr Leu Phe Arg Phe His Gly Ala Ser 
225                 230                 235                 240 


Gly Ala Ser Thr 
                


<210>  1199
<211>  418
<212>  PRT
<213>  Homo Sapiens

<400>  1199

Asn Lys Asp Pro Ser Tyr Ser Leu Gln Val Gln Arg Gln Val Pro Val 
1               5                   10                  15      


Pro Glu Gly Leu Cys Val Ile Val Ser Cys Asn Leu Ser Tyr Pro Arg 
            20                  25                  30          


Asp Gly Trp Asp Glu Ser Thr Ala Ala Tyr Gly Tyr Trp Phe Lys Gly 
        35                  40                  45              


Arg Thr Ser Pro Lys Thr Gly Ala Pro Val Ala Thr Asn Asn Gln Ser 
    50                  55                  60                  


Arg Glu Val Ala Met Ser Thr Arg Asp Arg Phe Gln Leu Thr Gly Asp 
65                  70                  75                  80  


Pro Gly Lys Gly Ser Cys Ser Leu Val Ile Arg Asp Ala Gln Arg Glu 
                85                  90                  95      


Asp Glu Ala Trp Tyr Phe Phe Arg Val Glu Arg Gly Ser Arg Val Arg 
            100                 105                 110         


His Ser Phe Leu Ser Asn Ala Phe Phe Leu Lys Val Thr Ala Leu Thr 
        115                 120                 125             


Gln Lys Pro Asp Val Tyr Ile Pro Glu Thr Leu Glu Pro Gly Gln Pro 
    130                 135                 140                 


Val Thr Val Ile Cys Val Phe Asn Trp Ala Phe Lys Lys Cys Pro Ala 
145                 150                 155                 160 


Pro Ser Phe Ser Trp Thr Gly Ala Ala Leu Ser Pro Arg Arg Thr Arg 
                165                 170                 175     


Pro Ser Thr Ser His Phe Ser Val Leu Ser Phe Thr Pro Ser Pro Gln 
            180                 185                 190         


Asp His Asp Thr Asp Leu Thr Cys His Val Asp Phe Ser Arg Lys Gly 
        195                 200                 205             


Val Ser Ala Gln Arg Thr Val Arg Leu Arg Val Ala Ser Leu Glu Leu 
    210                 215                 220                 


Gln Gly Asn Val Ile Tyr Leu Glu Val Gln Lys Gly Gln Phe Leu Arg 
225                 230                 235                 240 


Leu Leu Cys Ala Ala Asp Ser Gln Pro Pro Ala Thr Leu Ser Trp Val 
                245                 250                 255     


Leu Gln Asp Arg Val Leu Ser Ser Ser His Pro Trp Gly Pro Arg Thr 
            260                 265                 270         


Leu Gly Leu Glu Leu Pro Gly Val Lys Ala Gly Asp Ser Gly Arg Tyr 
        275                 280                 285             


Thr Cys Arg Ala Glu Asn Arg Leu Gly Ser Gln Gln Arg Ala Leu Asp 
    290                 295                 300                 


Leu Ser Val Gln Tyr Pro Pro Glu Asn Leu Arg Val Met Val Ser Gln 
305                 310                 315                 320 


Ala Asn Arg Thr Val Leu Glu Asn Leu Arg Asn Gly Thr Ser Leu Arg 
                325                 330                 335     


Val Leu Glu Gly Gln Ser Leu Arg Leu Val Cys Val Thr His Ser Ser 
            340                 345                 350         


Pro Pro Ala Arg Leu Ser Trp Thr Trp Gly Glu Gln Thr Val Gly Pro 
        355                 360                 365             


Ser Gln Pro Ser Asp Pro Gly Val Leu Gln Leu Pro Arg Val Gln Met 
    370                 375                 380                 


Glu His Glu Gly Glu Phe Thr Cys His Ala Arg His Pro Leu Gly Ser 
385                 390                 395                 400 


Gln Arg Val Ser Leu Ser Phe Ser Val His Cys Lys Ser Gly Pro Met 
                405                 410                 415     


Thr Gly 
        


<210>  1200
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  1200

Glu Lys Pro Val Tyr Glu Leu Gln Val Gln Lys Ser Val Thr Val Gln 
1               5                   10                  15      


Glu Gly Leu Cys Val Leu Val Pro Cys Ser Phe Ser Tyr Pro Trp Arg 
            20                  25                  30          


Ser Trp Tyr Ser Ser Pro Pro Leu Tyr Val Tyr Trp Phe Arg Asp Gly 
        35                  40                  45              


Glu Ile Pro Tyr Tyr Ala Glu Val Val Ala Thr Asn Asn Pro Asp Arg 
    50                  55                  60                  


Arg Val Lys Pro Glu Thr Gln Gly Arg Phe Arg Leu Leu Gly Asp Val 
65                  70                  75                  80  


Gln Lys Lys Asn Cys Ser Leu Ser Ile Gly Asp Ala Arg Met Glu Asp 
                85                  90                  95      


Thr Gly Ser Tyr Phe Phe Arg Val Glu Arg Gly Arg Asp Val Lys Tyr 
            100                 105                 110         


Ser Tyr Gln Gln Asn Lys Leu Asn Leu Glu Val Thr Ala Leu Ile Glu 
        115                 120                 125             


Lys Pro Asp Ile His Phe Leu Glu Pro Leu Glu Ser Gly Arg Pro Thr 
    130                 135                 140                 


Arg Leu Ser Cys Ser Leu Pro Gly Ser Cys Glu Ala Gly Pro Pro Leu 
145                 150                 155                 160 


Thr Phe Ser Trp Thr Gly Asn Ala Leu Ser Pro Leu Asp Pro Glu Thr 
                165                 170                 175     


Thr Arg Ser Ser Glu Leu Thr Leu Thr Pro Arg Pro Glu Asp His Gly 
            180                 185                 190         


Thr Asn Leu Thr Cys Gln Met Lys Arg Gln Gly Ala Gln Val Thr Thr 
        195                 200                 205             


Glu Arg Thr Val Gln Leu Asn Val Ser Tyr Ala Pro Gln Thr Ile Thr 
    210                 215                 220                 


Ile Phe Arg Asn Gly Ile Ala Leu Glu Ile Leu Gln Asn Thr Ser Tyr 
225                 230                 235                 240 


Leu Pro Val Leu Glu Gly Gln Ala Leu Arg Leu Leu Cys Asp Ala Pro 
                245                 250                 255     


Ser Asn Pro Pro Ala His Leu Ser Trp Phe Gln Gly Ser Pro Ala Leu 
            260                 265                 270         


Asn Ala Thr Pro Ile Ser Asn Thr Gly Ile Leu Glu Leu Arg Arg Val 
        275                 280                 285             


Arg Ser Ala Glu Glu Gly Gly Phe Thr Cys Arg Ala Gln His Pro Leu 
    290                 295                 300                 


Gly Phe Leu Gln Ile Phe Leu Asn Leu Ser Val Tyr Ser Leu Pro Gln 
305                 310                 315                 320 


Leu Leu Gly Pro Ser Cys Ser Trp Glu Ala Glu Gly Leu His Cys Arg 
                325                 330                 335     


Cys Ser Phe Arg Ala Arg Pro Ala Pro Ser Leu Cys Trp Arg Leu Glu 
            340                 345                 350         


Glu Lys Pro Leu Glu Gly Asn Ser Ser Gln Gly Ser Phe Lys Val Asn 
        355                 360                 365             


Ser Ser Ser Ala Gly Pro Trp Ala Asn Ser Ser Leu Ile Leu His Gly 
    370                 375                 380                 


Gly Leu Ser Ser Asp Leu Lys Val Ser Cys Lys Ala Trp Asn Ile Tyr 
385                 390                 395                 400 


Gly Ser Gln Ser Gly Ser Val Leu Leu Leu Gln Gly Arg Ser Asn Leu 
                405                 410                 415     


Gly Thr Gly Val Val Pro Ala Ala Leu 
            420                 425 


<210>  1201
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  1201

Gln Glu Arg Arg Phe Gln Leu Glu Gly Pro Glu Ser Leu Thr Val Gln 
1               5                   10                  15      


Glu Gly Leu Cys Val Leu Val Pro Cys Arg Leu Pro Thr Thr Leu Pro 
            20                  25                  30          


Ala Ser Tyr Tyr Gly Tyr Gly Tyr Trp Phe Leu Glu Gly Ala Asp Val 
        35                  40                  45              


Pro Val Ala Thr Asn Asp Pro Asp Glu Glu Val Gln Glu Glu Thr Arg 
    50                  55                  60                  


Gly Arg Phe His Leu Leu Trp Asp Pro Arg Arg Lys Asn Cys Ser Leu 
65                  70                  75                  80  


Ser Ile Arg Asp Ala Arg Arg Arg Asp Asn Ala Ala Tyr Phe Phe Arg 
                85                  90                  95      


Leu Lys Ser Lys Trp Met Lys Tyr Gly Tyr Thr Ser Ser Lys Leu Ser 
            100                 105                 110         


Val Arg Val Met Ala Leu Thr His Arg Pro Asn Ile Ser Ile Pro Gly 
        115                 120                 125             


Thr Leu Glu Ser Gly His Pro Ser Asn Leu Thr Cys Ser Val Pro Trp 
    130                 135                 140                 


Val Cys Glu Gln Gly Thr Pro Pro Ile Phe Ser Trp Met Ser Ala Ala 
145                 150                 155                 160 


Pro Thr Ser Leu Gly Pro Arg Thr Thr Gln Ser Ser Val Leu Thr Ile 
                165                 170                 175     


Thr Pro Arg Pro Gln Asp His Ser Thr Asn Leu Thr Cys Gln Val Thr 
            180                 185                 190         


Phe Pro Gly Ala Gly Val Thr Met Glu Arg Thr Ile Gln Leu Asn Val 
        195                 200                 205             


Ser Ser Phe Lys Ile Leu Gln Asn Thr Ser Ser Leu Pro Val Leu Glu 
    210                 215                 220                 


Gly Gln Ala Leu Arg Leu Leu Cys Asp Ala Asp Gly Asn Pro Pro Ala 
225                 230                 235                 240 


His Leu Ser Trp Phe Gln Gly Phe Pro Ala Leu Asn Ala Thr Pro Ile 
                245                 250                 255     


Ser Asn Thr Gly Val Leu Glu Leu Pro Gln Val Gly Ser Ala Glu Glu 
            260                 265                 270         


Gly Asp Phe Thr Cys Arg Ala Gln His Pro Leu Gly Ser Leu Gln Ile 
        275                 280                 285             


Ser Leu Ser Leu Phe Val His Trp Lys Pro Glu Gly Arg Ala Gly Gly 
    290                 295                 300                 


Val 
305 


<210>  1202
<211>  335
<212>  PRT
<213>  Homo Sapiens

<400>  1202

Gln Lys Ser Asn Arg Lys Asp Tyr Ser Leu Thr Met Gln Ser Ser Val 
1               5                   10                  15      


Thr Val Gln Glu Gly Met Cys Val His Val Arg Cys Ser Phe Ser Tyr 
            20                  25                  30          


Pro Val Asp Ser Gln Thr Asp Ser Asp Pro Val His Gly Tyr Trp Phe 
        35                  40                  45              


Arg Ala Gly Asn Asp Ile Ser Trp Lys Ala Pro Val Ala Thr Asn Asn 
    50                  55                  60                  


Pro Ala Trp Ala Val Gln Glu Glu Thr Arg Asp Arg Phe His Leu Leu 
65                  70                  75                  80  


Gly Asp Pro Gln Thr Lys Asn Cys Thr Leu Ser Ile Arg Asp Ala Arg 
                85                  90                  95      


Met Ser Asp Ala Gly Arg Tyr Phe Phe Arg Met Glu Lys Gly Asn Ile 
            100                 105                 110         


Lys Trp Asn Tyr Lys Tyr Asp Gln Leu Ser Val Asn Val Thr Ala Leu 
        115                 120                 125             


Thr His Arg Pro Asn Ile Leu Ile Pro Gly Thr Leu Glu Ser Gly Cys 
    130                 135                 140                 


Phe Gln Asn Leu Thr Cys Ser Val Pro Trp Ala Cys Glu Gln Gly Thr 
145                 150                 155                 160 


Pro Pro Met Ile Ser Trp Met Gly Thr Ser Val Ser Pro Leu His Pro 
                165                 170                 175     


Ser Thr Thr Arg Ser Ser Val Leu Thr Leu Ile Pro Gln Pro Gln His 
            180                 185                 190         


His Gly Thr Ser Leu Thr Cys Gln Val Thr Leu Pro Gly Ala Gly Val 
        195                 200                 205             


Thr Thr Asn Arg Thr Ile Gln Leu Asn Val Ser Tyr Pro Pro Gln Asn 
    210                 215                 220                 


Leu Thr Val Thr Val Phe Gln Gly Glu Gly Thr Ala Ser Thr Ala Leu 
225                 230                 235                 240 


Gly Asn Ser Ser Ser Leu Ser Val Leu Glu Gly Gln Ser Leu Arg Leu 
                245                 250                 255     


Val Cys Ala Val Asp Ser Asn Pro Pro Ala Arg Leu Ser Trp Thr Trp 
            260                 265                 270         


Arg Ser Leu Thr Leu Tyr Pro Ser Gln Pro Ser Asn Pro Leu Val Leu 
        275                 280                 285             


Glu Leu Gln Val His Leu Gly Asp Glu Gly Glu Phe Thr Cys Arg Ala 
    290                 295                 300                 


Gln Asn Ser Leu Gly Ser Gln His Val Ser Leu Asn Leu Ser Leu Gln 
305                 310                 315                 320 


Gln Glu Tyr Thr Gly Lys Met Arg Pro Val Ser Gly Val Leu Leu 
                325                 330                 335 


<210>  1203
<211>  347
<212>  PRT
<213>  Homo Sapiens

<400>  1203

Met Glu Gly Asp Arg Gln Tyr Gly Asp Gly Tyr Leu Leu Gln Val Gln 
1               5                   10                  15      


Glu Leu Val Thr Val Gln Glu Gly Leu Cys Val His Val Pro Cys Ser 
            20                  25                  30          


Phe Ser Tyr Pro Gln Asp Gly Trp Thr Asp Ser Asp Pro Val His Gly 
        35                  40                  45              


Tyr Trp Phe Arg Ala Gly Asp Arg Pro Tyr Gln Asp Ala Pro Val Ala 
    50                  55                  60                  


Thr Asn Asn Pro Asp Arg Glu Val Gln Ala Glu Thr Gln Gly Arg Phe 
65                  70                  75                  80  


Gln Leu Leu Gly Asp Ile Trp Ser Asn Asp Cys Ser Leu Ser Ile Arg 
                85                  90                  95      


Asp Ala Arg Lys Arg Asp Lys Gly Ser Tyr Phe Phe Arg Leu Glu Arg 
            100                 105                 110         


Gly Ser Met Lys Trp Ser Tyr Lys Ser Gln Leu Asn Tyr Lys Thr Lys 
        115                 120                 125             


Gln Leu Ser Val Phe Val Thr Ala Leu Thr His Arg Pro Asp Ile Leu 
    130                 135                 140                 


Ile Leu Gly Thr Leu Glu Ser Gly His Pro Arg Asn Leu Thr Cys Ser 
145                 150                 155                 160 


Val Pro Trp Ala Cys Lys Gln Gly Thr Pro Pro Met Ile Ser Trp Ile 
                165                 170                 175     


Gly Ala Ser Val Ser Ser Pro Gly Pro Thr Thr Ala Arg Ser Ser Val 
            180                 185                 190         


Leu Thr Leu Thr Pro Lys Pro Gln Asp His Gly Thr Ser Leu Thr Cys 
        195                 200                 205             


Gln Val Thr Leu Pro Gly Thr Gly Val Thr Thr Thr Ser Thr Val Arg 
    210                 215                 220                 


Leu Asp Val Ser Tyr Pro Pro Trp Asn Leu Thr Met Thr Val Phe Gln 
225                 230                 235                 240 


Gly Asp Ala Thr Ala Ser Thr Ala Leu Gly Asn Gly Ser Ser Leu Ser 
                245                 250                 255     


Val Leu Glu Gly Gln Ser Leu Arg Leu Val Cys Ala Val Asn Ser Asn 
            260                 265                 270         


Pro Pro Ala Arg Leu Ser Trp Thr Arg Gly Ser Leu Thr Leu Cys Pro 
        275                 280                 285             


Ser Arg Ser Ser Asn Pro Gly Leu Leu Glu Leu Pro Arg Val His Val 
    290                 295                 300                 


Arg Asp Glu Gly Glu Phe Thr Cys Arg Ala Gln Asn Ala Gln Gly Ser 
305                 310                 315                 320 


Gln His Ile Ser Leu Ser Leu Ser Leu Gln Asn Glu Gly Thr Gly Thr 
                325                 330                 335     


Ser Arg Pro Val Ser Gln Val Thr Leu Ala Ala 
            340                 345         


<210>  1204
<211>  331
<212>  PRT
<213>  Homo Sapiens

<400>  1204

Gln Thr Ser Lys Leu Leu Thr Met Gln Ser Ser Val Thr Val Gln Glu 
1               5                   10                  15      


Gly Leu Cys Val His Val Pro Cys Ser Phe Ser Tyr Pro Ser His Gly 
            20                  25                  30          


Trp Ile Tyr Pro Gly Pro Val Val His Gly Tyr Trp Phe Arg Glu Gly 
        35                  40                  45              


Ala Asn Thr Asp Gln Asp Ala Pro Val Ala Thr Asn Asn Pro Ala Arg 
    50                  55                  60                  


Ala Val Trp Glu Glu Thr Arg Asp Arg Phe His Leu Leu Gly Asp Pro 
65                  70                  75                  80  


His Thr Glu Asn Cys Thr Leu Ser Ile Arg Asp Ala Arg Arg Ser Asp 
                85                  90                  95      


Ala Gly Arg Tyr Phe Phe Arg Met Glu Lys Gly Ser Ile Lys Trp Asn 
            100                 105                 110         


Tyr Lys His His Arg Leu Ser Val Asn Val Thr Ala Leu Thr His Arg 
        115                 120                 125             


Pro Asn Ile Leu Ile Pro Gly Thr Leu Glu Ser Gly Cys Pro Gln Asn 
    130                 135                 140                 


Leu Thr Cys Ser Val Pro Trp Ala Cys Glu Gln Gly Thr Pro Pro Met 
145                 150                 155                 160 


Ile Ser Trp Ile Gly Thr Ser Val Ser Pro Leu Asp Pro Ser Thr Thr 
                165                 170                 175     


Arg Ser Ser Val Leu Thr Leu Ile Pro Gln Pro Gln Asp His Gly Thr 
            180                 185                 190         


Ser Leu Thr Cys Gln Val Thr Phe Pro Gly Ala Ser Val Thr Thr Asn 
        195                 200                 205             


Lys Thr Val His Leu Asn Val Ser Tyr Pro Pro Gln Asn Leu Thr Met 
    210                 215                 220                 


Thr Val Phe Gln Gly Asp Gly Thr Val Ser Thr Val Leu Gly Asn Gly 
225                 230                 235                 240 


Ser Ser Leu Ser Leu Pro Glu Gly Gln Ser Leu Arg Leu Val Cys Ala 
                245                 250                 255     


Val Asp Ala Val Asp Ser Asn Pro Pro Ala Arg Leu Ser Leu Ser Trp 
            260                 265                 270         


Arg Gly Leu Thr Leu Cys Pro Ser Gln Pro Ser Asn Pro Gly Val Leu 
        275                 280                 285             


Glu Leu Pro Trp Val His Leu Arg Asp Glu Ala Glu Phe Thr Cys Arg 
    290                 295                 300                 


Ala Gln Asn Pro Leu Gly Ser Gln Gln Val Tyr Leu Asn Val Ser Leu 
305                 310                 315                 320 


Gln Ser Lys Ala Thr Ser Gly Val Thr Gln Gly 
                325                 330     


<210>  1205
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  1205

Glu Glu Glu Leu Gln Val Ile Gln Pro Asp Lys Ser Val Ser Val Ala 
1               5                   10                  15      


Ala Gly Glu Ser Ala Ile Leu His Cys Thr Val Thr Ser Leu Ile Pro 
            20                  25                  30          


Val Gly Pro Ile Gln Trp Phe Arg Gly Ala Gly Pro Ala Arg Glu Leu 
        35                  40                  45              


Ile Tyr Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser 
    50                  55                  60                  


Glu Ser Thr Lys Arg Glu Asn Met Asp Phe Ser Ile Ser Ile Ser Asn 
65                  70                  75                  80  


Ile Thr Pro Ala Asp Ala Gly Thr Tyr Tyr Cys Val Lys Phe Arg Lys 
                85                  90                  95      


Gly Ser Pro Asp Thr Glu Phe Lys Ser Gly Ala Gly Thr Glu Leu Ser 
            100                 105                 110         


Val Arg Ala Lys Pro Ser Ala Pro Val Val Ser Gly Pro Ala Ala Arg 
        115                 120                 125             


Ala Thr Pro Gln His Thr Val Ser Phe Thr Cys Glu Ser His Gly Phe 
    130                 135                 140                 


Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe Lys Asn Gly Asn Glu Leu 
145                 150                 155                 160 


Ser Asp Phe Gln Thr Asn Val Asp Pro Val Gly Glu Ser Val Ser Tyr 
                165                 170                 175     


Ser Ile His Ser Thr Ala Lys Val Val Leu Thr Arg Glu Asp Val His 
            180                 185                 190         


Ser Gln Val Ile Cys Glu Val Ala His Val Thr Leu Gln Gly Asp Pro 
        195                 200                 205             


Leu Arg Gly Thr Ala Asn Leu Ser Glu Thr Ile Arg Val Pro Pro Thr 
    210                 215                 220                 


Leu Glu Val Thr Gln Gln Pro Val Arg Ala Glu Asn Gln Val Asn Val 
225                 230                 235                 240 


Thr Cys Gln Val Arg Lys Phe Tyr Pro Gln Arg Leu Gln Leu Thr Trp 
                245                 250                 255     


Leu Glu Asn Gly Asn Val Ser Arg Thr Glu Thr Ala Ser Thr Val Thr 
            260                 265                 270         


Glu Asn Lys Asp Gly Thr Tyr Asn Trp Met Ser Trp Leu Leu Val Asn 
        275                 280                 285             


Val Ser Ala His Arg Asp Asp Val Lys Leu Thr Cys Gln Val Glu His 
    290                 295                 300                 


Asp Gly Gln Pro Ala Val Ser Lys Ser His Asp Leu Lys Val Ser Ala 
305                 310                 315                 320 


His Pro Lys Glu Gln Gly Ser Asn Thr Ala Ala Glu Asn Thr Gly Ser 
                325                 330                 335     


Asn Glu Arg Asn Ile Tyr 
            340         


<210>  1206
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  1206

Glu Asp Glu Leu Gln Val Ile Gln Pro Glu Lys Ser Val Ser Val Ala 
1               5                   10                  15      


Ala Gly Glu Ser Ala Thr Leu Arg Cys Ala Met Thr Ser Leu Ile Pro 
            20                  25                  30          


Val Gly Pro Ile Met Trp Phe Arg Gly Ala Gly Ala Gly Arg Glu Leu 
        35                  40                  45              


Ile Tyr Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser 
    50                  55                  60                  


Glu Leu Thr Lys Arg Asn Asn Leu Asp Phe Ser Ile Ser Ile Ser Asn 
65                  70                  75                  80  


Ile Thr Pro Ala Asp Ala Gly Thr Tyr Tyr Cys Val Lys Phe Arg Lys 
                85                  90                  95      


Gly Ser Pro Asp Asp Val Glu Phe Lys Ser Gly Ala Gly Thr Glu Leu 
            100                 105                 110         


Ser Val Arg Ala Lys Pro Ser Ala Pro Val Val Ser Gly Pro Ala Val 
        115                 120                 125             


Arg Ala Thr Pro Glu His Thr Val Ser Phe Thr Cys Glu Ser His Gly 
    130                 135                 140                 


Phe Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe Lys Asn Gly Asn Glu 
145                 150                 155                 160 


Leu Ser Asp Phe Gln Thr Asn Val Asp Pro Ala Gly Asp Ser Val Ser 
                165                 170                 175     


Tyr Ser Ile His Ser Thr Ala Arg Val Val Leu Thr Arg Gly Asp Val 
            180                 185                 190         


His Ser Gln Val Ile Cys Glu Ile Ala His Ile Thr Leu Gln Gly Asp 
        195                 200                 205             


Pro Leu Arg Gly Thr Ala Asn Leu Ser Glu Ala Ile Arg Val Pro Pro 
    210                 215                 220                 


Thr Leu Glu Val Thr Gln Gln Pro Met Arg Ala Glu Asn Gln Ala Asn 
225                 230                 235                 240 


Val Thr Cys Gln Val Ser Asn Phe Tyr Pro Arg Gly Leu Gln Leu Thr 
                245                 250                 255     


Trp Leu Glu Asn Gly Asn Val Ser Arg Thr Glu Thr Ala Ser Thr Leu 
            260                 265                 270         


Ile Glu Asn Lys Asp Gly Thr Tyr Asn Trp Met Ser Trp Leu Leu Val 
        275                 280                 285             


Asn Thr Cys Ala His Arg Asp Asp Val Val Leu Thr Cys Gln Val Glu 
    290                 295                 300                 


His Asp Gly Gln Gln Ala Val Ser Lys Ser Tyr Ala Leu Glu Ile Ser 
305                 310                 315                 320 


Ala His Gln Lys Glu His Gly Ser Asp Ile Thr His Glu Ala Ala Leu 
                325                 330                 335     


Ala Pro Thr Ala Pro Leu 
            340         


<210>  1207
<211>  255
<212>  PRT
<213>  Homo Sapiens

<400>  1207

Gln Ser Ser Arg Asn Asp Trp Gln Val Leu Gln Pro Glu Gly Pro Met 
1               5                   10                  15      


Leu Val Ala Glu Gly Glu Thr Leu Leu Leu Arg Cys Met Val Val Gly 
            20                  25                  30          


Ser Cys Thr Asp Gly Met Ile Lys Trp Val Lys Val Ser Thr Gln Asp 
        35                  40                  45              


Gln Gln Glu Ile Tyr Asn Phe Lys Arg Gly Ser Phe Pro Gly Val Met 
    50                  55                  60                  


Pro Met Ile Gln Arg Thr Ser Glu Pro Leu Asn Cys Asp Tyr Ser Ile 
65                  70                  75                  80  


Tyr Ile His Asn Val Thr Arg Glu His Thr Gly Thr Tyr His Cys Val 
                85                  90                  95      


Arg Phe Asp Gly Leu Ser Glu His Ser Glu Met Lys Ser Asp Glu Gly 
            100                 105                 110         


Thr Ser Val Leu Val Lys Gly Ala Gly Asp Pro Glu Pro Asp Leu Trp 
        115                 120                 125             


Ile Ile Gln Pro Gln Glu Leu Val Leu Gly Thr Thr Gly Asp Thr Val 
    130                 135                 140                 


Phe Leu Asn Cys Thr Val Leu Gly Asp Gly Pro Pro Gly Pro Ile Arg 
145                 150                 155                 160 


Trp Phe Gln Gly Ala Gly Leu Ser Arg Glu Ala Ile Tyr Asn Phe Gly 
                165                 170                 175     


Gly Ile Ser His Pro Lys Glu Thr Ala Val Gln Ala Ser Asn Asn Asp 
            180                 185                 190         


Phe Ser Ile Leu Leu Gln Asn Val Ser Ser Glu Asp Ala Gly Thr Tyr 
        195                 200                 205             


Tyr Cys Val Lys Phe Gln Arg Lys Pro Asn Arg Gln Tyr Leu Ser Gly 
    210                 215                 220                 


Gln Gly Thr Ser Leu Lys Val Lys Ala Lys Ser Thr Ser Ser Lys Glu 
225                 230                 235                 240 


Ala Glu Phe Thr Ser Glu Pro Ala Thr Glu Met Ser Pro Thr Gly 
                245                 250                 255 


<210>  1208
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  1208

Glu Glu Glu Leu Gln Met Ile Gln Pro Glu Lys Leu Leu Leu Val Thr 
1               5                   10                  15      


Val Gly Lys Thr Ala Thr Leu His Cys Thr Val Thr Ser Leu Leu Pro 
            20                  25                  30          


Val Gly Pro Val Leu Trp Phe Arg Gly Val Gly Pro Gly Arg Glu Leu 
        35                  40                  45              


Ile Tyr Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser 
    50                  55                  60                  


Asp Leu Thr Lys Arg Asn Asn Met Asp Phe Ser Ile Arg Ile Ser Ser 
65                  70                  75                  80  


Ile Thr Pro Ala Asp Val Gly Thr Tyr Tyr Cys Val Lys Phe Arg Lys 
                85                  90                  95      


Gly Ser Pro Glu Asn Val Glu Phe Lys Ser Gly Pro Gly Thr Glu Met 
            100                 105                 110         


Ala Leu Gly Ala Lys Pro Ser Ala Pro Val Val Leu Gly Pro Ala Ala 
        115                 120                 125             


Arg Thr Thr Pro Glu His Thr Val Ser Phe Thr Cys Glu Ser His Gly 
    130                 135                 140                 


Phe Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe Lys Asn Gly Asn Glu 
145                 150                 155                 160 


Leu Ser Asp Phe Gln Thr Asn Val Asp Pro Thr Gly Gln Ser Val Ala 
                165                 170                 175     


Tyr Ser Ile Arg Ser Thr Ala Arg Val Val Leu Asp Pro Trp Asp Val 
            180                 185                 190         


Arg Ser Gln Val Ile Cys Glu Val Ala His Val Thr Leu Gln Gly Asp 
        195                 200                 205             


Pro Leu Arg Gly Thr Ala Asn Leu Ser Glu Ala Ile Arg Val Pro Pro 
    210                 215                 220                 


Thr Leu Glu Val Thr Gln Gln Pro Met Arg Val Gly Asn Gln Val Asn 
225                 230                 235                 240 


Val Thr Cys Gln Val Arg Lys Phe Tyr Pro Gln Ser Leu Gln Leu Thr 
                245                 250                 255     


Trp Ser Glu Asn Gly Asn Val Cys Gln Arg Glu Thr Ala Ser Thr Leu 
            260                 265                 270         


Thr Glu Asn Lys Asp Gly Thr Tyr Asn Trp Thr Ser Trp Phe Leu Val 
        275                 280                 285             


Asn Ile Ser Asp Gln Arg Asp Asp Val Val Leu Thr Cys Gln Val Lys 
    290                 295                 300                 


His Asp Gly Gln Leu Ala Val Ser Lys Arg Leu Ala Leu Glu Val Thr 
305                 310                 315                 320 


Val His Gln Lys Asp Gln Ser Ser Asp Ala Thr Pro 
                325                 330         


<210>  1209
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  1209

Ala Ser Tyr Gly Thr Gly Gly Arg Met Met Asn Cys Pro Lys Ile Leu 
1               5                   10                  15      


Arg Gln Leu Gly Ser Lys Val Leu Leu Pro Leu Thr Tyr Glu Arg Ile 
            20                  25                  30          


Asn Lys Ser Met Asn Lys Ser Ile His Ile Val Val Thr Met Ala Lys 
        35                  40                  45              


Ser Leu Glu Asn Ser Val Glu Asn Lys Ile Val Ser Leu Asp Pro Ser 
    50                  55                  60                  


Glu Ala Gly Pro Pro Arg Tyr Leu Gly Asp Arg Tyr Lys Phe Tyr Leu 
65                  70                  75                  80  


Glu Asn Leu Thr Leu Gly Ile Arg Glu Ser Arg Lys Glu Asp Glu Gly 
                85                  90                  95      


Trp Tyr Leu Met Thr Leu Glu Lys Asn Val Ser Val Gln Arg Phe Cys 
            100                 105                 110         


Leu Gln Leu Arg Leu Tyr Glu Gln Val Ser Thr Pro Glu Ile Lys Val 
        115                 120                 125             


Leu Asn Lys Thr Gln Glu Asn Gly Thr Cys Thr Leu Ile Leu Gly Cys 
    130                 135                 140                 


Thr Val Glu Lys Gly Asp His Val Ala Tyr Ser Trp Ser Glu Lys Ala 
145                 150                 155                 160 


Gly Thr His Pro Leu Asn Pro Ala Asn Ser Ser His Leu Leu Ser Leu 
                165                 170                 175     


Thr Leu Gly Pro Gln His Ala Asp Asn Ile Tyr Ile Cys Thr Val Ser 
            180                 185                 190         


Asn Pro Ile Ser Asn Asn Ser Gln Thr Phe Ser Pro Trp Pro Gly Cys 
        195                 200                 205             


Arg Thr Asp Pro Ser Glu Thr Lys Pro 
    210                 215         


<210>  1210
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  1210

Gln Ser Ser Leu Thr Pro Leu Met Val Asn Gly Ile Leu Gly Glu Ser 
1               5                   10                  15      


Val Thr Leu Pro Leu Glu Phe Pro Ala Gly Glu Lys Val Asn Phe Ile 
            20                  25                  30          


Thr Trp Leu Phe Asn Glu Thr Ser Leu Ala Phe Ile Val Pro His Glu 
        35                  40                  45              


Thr Lys Ser Pro Glu Ile His Val Thr Asn Pro Lys Gln Gly Lys Arg 
    50                  55                  60                  


Leu Asn Phe Thr Gln Ser Tyr Ser Leu Gln Leu Ser Asn Leu Lys Met 
65                  70                  75                  80  


Glu Asp Thr Gly Ser Tyr Arg Ala Gln Ile Ser Thr Lys Thr Ser Ala 
                85                  90                  95      


Lys Leu Ser Ser Tyr Thr Leu Arg Ile Leu Arg Gln Leu Arg Asn Ile 
            100                 105                 110         


Gln Val Thr Asn His Ser Gln Leu Phe Gln Asn Met Thr Cys Glu Leu 
        115                 120                 125             


His Leu Thr Cys Ser Val Glu Asp Ala Asp Asp Asn Val Ser Phe Arg 
    130                 135                 140                 


Trp Glu Ala Leu Gly Asn Thr Leu Ser Ser Gln Pro Asn Leu Thr Val 
145                 150                 155                 160 


Ser Trp Asp Pro Arg Ile Ser Ser Glu Gln Asp Tyr Thr Cys Ile Ala 
                165                 170                 175     


Glu Asn Ala Val Ser Asn Leu Ser Phe Ser Val Ser Ala Gln Lys Leu 
            180                 185                 190         


Cys Glu Asp Val Lys Ile Gln Tyr Thr Asp Thr Lys Met 
        195                 200                 205 


<210>  1211
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  1211

Ser Gly Pro Val Lys Glu Leu Val Gly Ser Val Gly Gly Ala Val Thr 
1               5                   10                  15      


Phe Pro Leu Lys Ser Lys Val Lys Gln Val Asp Ser Ile Val Trp Thr 
            20                  25                  30          


Phe Asn Thr Thr Pro Leu Val Thr Ile Gln Pro Glu Gly Gly Thr Ile 
        35                  40                  45              


Ile Val Thr Gln Asn Arg Asn Arg Glu Arg Val Asp Phe Pro Asp Gly 
    50                  55                  60                  


Gly Tyr Ser Leu Lys Leu Ser Lys Leu Lys Lys Asn Asp Ser Gly Ile 
65                  70                  75                  80  


Tyr Tyr Val Gly Ile Tyr Ser Ser Ser Leu Gln Gln Pro Ser Thr Gln 
                85                  90                  95      


Glu Tyr Val Leu His Val Tyr Glu His Leu Ser Lys Pro Lys Val Thr 
            100                 105                 110         


Met Gly Leu Gln Ser Asn Lys Asn Gly Thr Cys Val Thr Asn Leu Thr 
        115                 120                 125             


Cys Cys Met Glu His Gly Glu Glu Asp Val Ile Tyr Thr Trp Lys Ala 
    130                 135                 140                 


Leu Gly Gln Ala Ala Asn Glu Ser His Asn Gly Ser Ile Leu Pro Ile 
145                 150                 155                 160 


Ser Trp Arg Trp Gly Glu Ser Asp Met Thr Phe Ile Cys Val Ala Arg 
                165                 170                 175     


Asn Pro Val Ser Arg Asn Phe Ser Ser Pro Ile Leu Ala Arg Lys Leu 
            180                 185                 190         


Cys Glu Gly Ala Ala Asp Asp Pro Asp Ser Ser Met 
        195                 200                 


<210>  1212
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  1212

Ala Gln Val Leu Ser Lys Val Gly Gly Ser Val Leu Leu Val Ala Ala 
1               5                   10                  15      


Arg Pro Pro Gly Phe Gln Val Arg Glu Ala Ile Trp Arg Ser Leu Trp 
            20                  25                  30          


Pro Ser Glu Glu Leu Leu Ala Thr Phe Phe Arg Gly Ser Leu Glu Thr 
        35                  40                  45              


Leu Tyr His Ser Arg Phe Leu Gly Arg Ala Gln Leu His Ser Asn Leu 
    50                  55                  60                  


Ser Leu Glu Leu Gly Pro Leu Glu Ser Gly Asp Ser Gly Asn Phe Ser 
65                  70                  75                  80  


Val Leu Met Val Asp Thr Arg Gly Gln Pro Trp Thr Gln Thr Leu Gln 
                85                  90                  95      


Leu Lys Val Tyr Asp Ala Val Pro Arg Pro Val Val Gln Val Phe Ile 
            100                 105                 110         


Ala Val Glu Arg Asp Ala Gln Pro Ser Lys Thr Cys Gln Val Phe Leu 
        115                 120                 125             


Ser Cys Trp Ala Pro Asn Ile Ser Glu Ile Thr Tyr Ser Trp Arg Arg 
    130                 135                 140                 


Glu Thr Thr Met Asp Phe Gly Met Glu Pro His Ser Leu Phe Thr Asp 
145                 150                 155                 160 


Gly Gln Val Leu Ser Ile Ser Leu Gly Pro Gly Asp Arg Asp Val Ala 
                165                 170                 175     


Tyr Ser Cys Ile Val Ser Asn Pro Val Ser Trp Asp Leu Ala Thr Val 
            180                 185                 190         


Thr Pro Trp Asp Ser Cys His His Glu Ala Ala Pro Gly Lys Ala Ser 
        195                 200                 205             


Tyr Lys Asp 
    210     


<210>  1213
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  1213

Arg Arg Leu Trp Arg Trp Cys Gly Ser Glu Glu Val Val Ala Val Leu 
1               5                   10                  15      


Gln Glu Ser Ile Ser Leu Pro Leu Glu Ile Pro Pro Asp Glu Glu Val 
            20                  25                  30          


Glu Asn Ile Ile Trp Ser Ser His Lys Ser Leu Ala Thr Val Val Pro 
        35                  40                  45              


Gly Lys Glu Gly His Pro Ala Thr Ile Met Val Thr Asn Pro His Tyr 
    50                  55                  60                  


Gln Gly Gln Val Ser Phe Leu Asp Pro Ser Tyr Ser Leu His Ile Ser 
65                  70                  75                  80  


Asn Leu Ser Trp Glu Asp Ser Gly Leu Tyr Gln Ala Gln Val Asn Leu 
                85                  90                  95      


Arg Thr Ser Gln Ile Ser Thr Met Gln Gln Tyr Asn Leu Cys Val Tyr 
            100                 105                 110         


Arg Trp Leu Ser Glu Pro Gln Ile Thr Val Asn Phe Glu Ser Ser Gly 
        115                 120                 125             


Glu Gly Ala Cys Ser Met Ser Leu Val Cys Ser Val Glu Lys Ala Gly 
    130                 135                 140                 


Met Asp Met Thr Tyr Ser Trp Leu Ser Arg Gly Asp Ser Thr Tyr Thr 
145                 150                 155                 160 


Phe His Glu Gly Pro Val Leu Ser Thr Ser Trp Arg Pro Gly Asp Ser 
                165                 170                 175     


Ala Leu Ser Tyr Thr Cys Arg Ala Asn Asn Pro Ile Ser Asn Val Ser 
            180                 185                 190         


Ser Cys Pro Ile Pro Asp Gly Pro Phe Tyr Ala Asp Pro Asn Tyr Ala 
        195                 200                 205             


Ser Glu Lys Pro Ser Thr Ala Phe Cys Leu 
    210                 215             


<210>  1214
<211>  1499
<212>  PRT
<213>  Homo Sapiens

<400>  1214

Gln Cys Ser Cys Ser Gly Ser Thr Val Asp Cys His Gly Leu Ala Leu 
1               5                   10                  15      


Arg Ser Val Pro Arg Asn Ile Pro Arg Asn Thr Glu Arg Leu Asp Leu 
            20                  25                  30          


Asn Gly Asn Asn Ile Thr Arg Ile Thr Lys Thr Asp Phe Ala Gly Leu 
        35                  40                  45              


Arg His Leu Arg Val Leu Gln Leu Met Glu Asn Lys Ile Ser Thr Ile 
    50                  55                  60                  


Glu Arg Gly Ala Phe Gln Asp Leu Lys Glu Leu Glu Arg Leu Arg Leu 
65                  70                  75                  80  


Asn Arg Asn His Leu Gln Leu Phe Pro Glu Leu Leu Phe Leu Gly Thr 
                85                  90                  95      


Ala Lys Leu Tyr Arg Leu Asp Leu Ser Glu Asn Gln Ile Gln Ala Ile 
            100                 105                 110         


Pro Arg Lys Ala Phe Arg Gly Ala Val Asp Ile Lys Asn Leu Gln Leu 
        115                 120                 125             


Asp Tyr Asn Gln Ile Ser Cys Ile Glu Asp Gly Ala Phe Arg Ala Leu 
    130                 135                 140                 


Arg Asp Leu Glu Val Leu Thr Leu Asn Asn Asn Asn Ile Thr Arg Leu 
145                 150                 155                 160 


Ser Val Ala Ser Phe Asn His Met Pro Lys Leu Arg Thr Phe Arg Leu 
                165                 170                 175     


His Ser Asn Asn Leu Tyr Cys Asp Cys His Leu Ala Trp Leu Ser Asp 
            180                 185                 190         


Trp Leu Arg Gln Arg Pro Arg Val Gly Leu Tyr Thr Gln Cys Met Gly 
        195                 200                 205             


Pro Ser His Leu Arg Gly His Asn Val Ala Glu Val Gln Lys Arg Glu 
    210                 215                 220                 


Phe Val Cys Ser Gly His Gln Ser Phe Met Ala Pro Ser Cys Ser Val 
225                 230                 235                 240 


Leu His Cys Pro Ala Ala Cys Thr Cys Ser Asn Asn Ile Val Asp Cys 
                245                 250                 255     


Arg Gly Lys Gly Leu Thr Glu Ile Pro Thr Asn Leu Pro Glu Thr Ile 
            260                 265                 270         


Thr Glu Ile Arg Leu Glu Gln Asn Thr Ile Lys Val Ile Pro Pro Gly 
        275                 280                 285             


Ala Phe Ser Pro Tyr Lys Lys Leu Arg Arg Ile Asp Leu Ser Asn Asn 
    290                 295                 300                 


Gln Ile Ser Glu Leu Ala Pro Asp Ala Phe Gln Gly Leu Arg Ser Leu 
305                 310                 315                 320 


Asn Ser Leu Val Leu Tyr Gly Asn Lys Ile Thr Glu Leu Pro Lys Ser 
                325                 330                 335     


Leu Phe Glu Gly Leu Phe Ser Leu Gln Leu Leu Leu Leu Asn Ala Asn 
            340                 345                 350         


Lys Ile Asn Cys Leu Arg Val Asp Ala Phe Gln Asp Leu His Asn Leu 
        355                 360                 365             


Asn Leu Leu Ser Leu Tyr Asp Asn Lys Leu Gln Thr Ile Ala Lys Gly 
    370                 375                 380                 


Thr Phe Ser Pro Leu Arg Ala Ile Gln Thr Met His Leu Ala Gln Asn 
385                 390                 395                 400 


Pro Phe Ile Cys Asp Cys His Leu Lys Trp Leu Ala Asp Tyr Leu His 
                405                 410                 415     


Thr Asn Pro Ile Glu Thr Ser Gly Ala Arg Cys Thr Ser Pro Arg Arg 
            420                 425                 430         


Leu Ala Asn Lys Arg Ile Gly Gln Ile Lys Ser Lys Lys Phe Arg Cys 
        435                 440                 445             


Ser Ala Lys Glu Gln Tyr Phe Ile Pro Gly Thr Glu Asp Tyr Arg Ser 
    450                 455                 460                 


Lys Leu Ser Gly Asp Cys Phe Ala Asp Leu Ala Cys Pro Glu Lys Cys 
465                 470                 475                 480 


Arg Cys Glu Gly Thr Thr Val Asp Cys Ser Asn Gln Lys Leu Asn Lys 
                485                 490                 495     


Ile Pro Glu His Ile Pro Gln Tyr Thr Ala Glu Leu Arg Leu Asn Asn 
            500                 505                 510         


Asn Glu Phe Thr Val Leu Glu Ala Thr Gly Ile Phe Lys Lys Leu Pro 
        515                 520                 525             


Gln Leu Arg Lys Ile Asn Phe Ser Asn Asn Lys Ile Thr Asp Ile Glu 
    530                 535                 540                 


Glu Gly Ala Phe Glu Gly Ala Ser Gly Val Asn Glu Ile Leu Leu Thr 
545                 550                 555                 560 


Ser Asn Arg Leu Glu Asn Val Gln His Lys Met Phe Lys Gly Leu Glu 
                565                 570                 575     


Ser Leu Lys Thr Leu Met Leu Arg Ser Asn Arg Ile Thr Cys Val Gly 
            580                 585                 590         


Asn Asp Ser Phe Ile Gly Leu Ser Ser Val Arg Leu Leu Ser Leu Tyr 
        595                 600                 605             


Asp Asn Gln Ile Thr Thr Val Ala Pro Gly Ala Phe Asp Thr Leu His 
    610                 615                 620                 


Ser Leu Ser Thr Leu Asn Leu Leu Ala Asn Pro Phe Asn Cys Asn Cys 
625                 630                 635                 640 


Tyr Leu Ala Trp Leu Gly Glu Trp Leu Arg Lys Lys Arg Ile Val Thr 
                645                 650                 655     


Gly Asn Pro Arg Cys Gln Lys Pro Tyr Phe Leu Lys Glu Ile Pro Ile 
            660                 665                 670         


Gln Asp Val Ala Ile Gln Asp Phe Thr Cys Asp Asp Gly Asn Asp Asp 
        675                 680                 685             


Asn Ser Cys Ser Pro Leu Ser Arg Cys Pro Thr Glu Cys Thr Cys Leu 
    690                 695                 700                 


Asp Thr Val Val Arg Cys Ser Asn Lys Gly Leu Lys Val Leu Pro Lys 
705                 710                 715                 720 


Gly Ile Pro Arg Asp Val Thr Glu Leu Tyr Leu Asp Gly Asn Gln Phe 
                725                 730                 735     


Thr Leu Val Pro Lys Glu Leu Ser Asn Tyr Lys His Leu Thr Leu Ile 
            740                 745                 750         


Asp Leu Ser Asn Asn Arg Ile Ser Thr Leu Ser Asn Gln Ser Phe Ser 
        755                 760                 765             


Asn Met Thr Gln Leu Leu Thr Leu Ile Leu Ser Tyr Asn Arg Leu Arg 
    770                 775                 780                 


Cys Ile Pro Pro Arg Thr Phe Asp Gly Leu Lys Ser Leu Arg Leu Leu 
785                 790                 795                 800 


Ser Leu His Gly Asn Asp Ile Ser Val Val Pro Glu Gly Ala Phe Asn 
                805                 810                 815     


Asp Leu Ser Ala Leu Ser His Leu Ala Ile Gly Ala Asn Pro Leu Tyr 
            820                 825                 830         


Cys Asp Cys Asn Met Gln Trp Leu Ser Asp Trp Val Lys Ser Glu Tyr 
        835                 840                 845             


Lys Glu Pro Gly Ile Ala Arg Cys Ala Gly Pro Gly Glu Met Ala Asp 
    850                 855                 860                 


Lys Leu Leu Leu Thr Thr Pro Ser Lys Lys Phe Thr Cys Gln Gly Pro 
865                 870                 875                 880 


Val Asp Val Asn Ile Leu Ala Lys Cys Asn Pro Cys Leu Ser Asn Pro 
                885                 890                 895     


Cys Lys Asn Asp Gly Thr Cys Asn Ser Asp Pro Val Asp Phe Tyr Arg 
            900                 905                 910         


Cys Thr Cys Pro Tyr Gly Phe Lys Gly Gln Asp Cys Asp Val Pro Ile 
        915                 920                 925             


His Ala Cys Ile Ser Asn Pro Cys Lys His Gly Gly Thr Cys His Leu 
    930                 935                 940                 


Lys Glu Gly Glu Glu Asp Gly Phe Trp Cys Ile Cys Ala Asp Gly Phe 
945                 950                 955                 960 


Glu Gly Glu Asn Cys Glu Val Asn Val Asp Asp Cys Glu Asp Asn Asp 
                965                 970                 975     


Cys Glu Asn Asn Ser Thr Cys Val Asp Gly Ile Asn Asn Tyr Thr Cys 
            980                 985                 990         


Leu Cys Pro Pro Glu Tyr Thr Gly  Glu Leu Cys Glu Glu  Lys Leu Asp 
        995                 1000                 1005             


Phe Cys  Ala Gln Asp Leu Asn  Pro Cys Gln His Asp  Ser Lys Cys 
    1010                 1015                 1020             


Ile Leu  Thr Pro Lys Gly Phe  Lys Cys Asp Cys Thr  Pro Gly Tyr 
    1025                 1030                 1035             


Val Gly  Glu His Cys Asp Ile  Asp Phe Asp Asp Cys  Gln Asp Asn 
    1040                 1045                 1050             


Lys Cys  Lys Asn Gly Ala His  Cys Thr Asp Ala Val  Asn Gly Tyr 
    1055                 1060                 1065             


Thr Cys  Ile Cys Pro Glu Gly  Tyr Ser Gly Leu Phe  Cys Glu Phe 
    1070                 1075                 1080             


Ser Pro  Pro Met Val Leu Pro  Arg Thr Ser Pro Cys  Asp Asn Phe 
    1085                 1090                 1095             


Asp Cys  Gln Asn Gly Ala Gln  Cys Ile Val Arg Ile  Asn Glu Pro 
    1100                 1105                 1110             


Ile Cys  Gln Cys Leu Pro Gly  Tyr Gln Gly Glu Lys  Cys Glu Lys 
    1115                 1120                 1125             


Leu Val  Ser Val Asn Phe Ile  Asn Lys Glu Ser Tyr  Leu Gln Ile 
    1130                 1135                 1140             


Pro Ser  Ala Lys Val Arg Pro  Gln Thr Asn Ile Thr  Leu Gln Ile 
    1145                 1150                 1155             


Ala Thr  Asp Glu Asp Ser Gly  Ile Leu Leu Tyr Lys  Gly Asp Lys 
    1160                 1165                 1170             


Asp His  Ile Ala Val Glu Leu  Tyr Arg Gly Arg Val  Arg Ala Ser 
    1175                 1180                 1185             


Tyr Asp  Thr Gly Ser His Pro  Ala Ser Ala Ile Tyr  Ser Val Glu 
    1190                 1195                 1200             


Thr Ile  Asn Asp Gly Asn Phe  His Ile Val Glu Leu  Leu Ala Leu 
    1205                 1210                 1215             


Asp Gln  Ser Leu Ser Leu Ser  Val Asp Gly Gly Asn  Pro Lys Ile 
    1220                 1225                 1230             


Ile Thr  Asn Leu Ser Lys Gln  Ser Thr Leu Asn Phe  Asp Ser Pro 
    1235                 1240                 1245             


Leu Tyr  Val Gly Gly Met Pro  Gly Lys Ser Asn Val  Ala Ser Leu 
    1250                 1255                 1260             


Arg Gln  Ala Pro Gly Gln Asn  Gly Thr Ser Phe His  Gly Cys Ile 
    1265                 1270                 1275             


Arg Asn  Leu Tyr Ile Asn Ser  Glu Leu Gln Asp Phe  Gln Lys Val 
    1280                 1285                 1290             


Pro Met  Gln Thr Gly Ile Leu  Pro Gly Cys Glu Pro  Cys His Lys 
    1295                 1300                 1305             


Lys Val  Cys Ala His Gly Thr  Cys Gln Pro Ser Ser  Gln Ala Gly 
    1310                 1315                 1320             


Phe Thr  Cys Glu Cys Gln Glu  Gly Trp Met Gly Pro  Leu Cys Asp 
    1325                 1330                 1335             


Gln Arg  Thr Asn Asp Pro Cys  Leu Gly Asn Lys Cys  Val His Gly 
    1340                 1345                 1350             


Thr Cys  Leu Pro Ile Asn Ala  Phe Ser Tyr Ser Cys  Lys Cys Leu 
    1355                 1360                 1365             


Glu Gly  His Gly Gly Val Leu  Cys Asp Glu Glu Glu  Asp Leu Phe 
    1370                 1375                 1380             


Asn Pro  Cys Gln Ala Ile Lys  Cys Lys His Gly Lys  Cys Arg Leu 
    1385                 1390                 1395             


Ser Gly  Leu Gly Gln Pro Tyr  Cys Glu Cys Ser Ser  Gly Tyr Thr 
    1400                 1405                 1410             


Gly Asp  Ser Cys Asp Arg Glu  Ile Ser Cys Arg Gly  Glu Arg Ile 
    1415                 1420                 1425             


Arg Asp  Tyr Tyr Gln Lys Gln  Gln Gly Tyr Ala Ala  Cys Gln Thr 
    1430                 1435                 1440             


Thr Lys  Lys Val Ser Arg Leu  Glu Cys Arg Gly Gly  Cys Ala Gly 
    1445                 1450                 1455             


Gly Gln  Cys Cys Gly Pro Leu  Arg Ser Lys Arg Arg  Lys Tyr Ser 
    1460                 1465                 1470             


Phe Glu  Cys Thr Asp Gly Ser  Ser Phe Val Asp Glu  Val Glu Lys 
    1475                 1480                 1485             


Val Val  Lys Cys Gly Cys Thr  Arg Cys Val Ser 
    1490                 1495                 


<210>  1215
<211>  528
<212>  PRT
<213>  Homo Sapiens

<400>  1215

Asn Pro Asp Asp Cys Glu Asp Asn Asp Cys Glu Asn Asn Ala Thr Cys 
1               5                   10                  15      


Val Asp Gly Ile Asn Asn Tyr Val Cys Ile Cys Pro Pro Asn Tyr Thr 
            20                  25                  30          


Gly Glu Leu Cys Asp Glu Val Ile Asp His Cys Val Pro Glu Leu Asn 
        35                  40                  45              


Leu Cys Gln His Glu Ala Lys Cys Ile Pro Leu Asp Lys Gly Phe Ser 
    50                  55                  60                  


Cys Glu Cys Val Pro Gly Tyr Ser Gly Lys Leu Cys Glu Thr Asp Asn 
65                  70                  75                  80  


Asp Asp Cys Val Ala His Lys Cys Arg His Gly Ala Gln Cys Val Asp 
                85                  90                  95      


Thr Ile Asn Gly Tyr Thr Cys Thr Cys Pro Gln Gly Phe Ser Gly Pro 
            100                 105                 110         


Phe Cys Glu His Pro Pro Pro Met Val Leu Leu Gln Thr Ser Pro Cys 
        115                 120                 125             


Asp Gln Tyr Glu Cys Gln Asn Gly Ala Gln Cys Ile Val Val Gln Gln 
    130                 135                 140                 


Glu Pro Thr Cys Arg Cys Pro Pro Gly Phe Ala Gly Pro Arg Cys Glu 
145                 150                 155                 160 


Lys Leu Ile Thr Val Asn Phe Val Gly Lys Asp Ser Tyr Val Glu Leu 
                165                 170                 175     


Ala Ser Ala Lys Val Arg Pro Gln Ala Asn Ile Ser Leu Gln Val Ala 
            180                 185                 190         


Thr Asp Lys Asp Asn Gly Ile Leu Leu Tyr Lys Gly Asp Asn Asp Pro 
        195                 200                 205             


Leu Ala Leu Glu Leu Tyr Gln Gly His Val Arg Leu Val Tyr Asp Ser 
    210                 215                 220                 


Leu Ser Ser Pro Pro Thr Thr Val Tyr Ser Val Glu Thr Val Asn Asp 
225                 230                 235                 240 


Gly Gln Phe His Ser Val Glu Leu Val Thr Leu Asn Gln Thr Leu Asn 
                245                 250                 255     


Leu Val Val Asp Lys Gly Thr Pro Lys Ser Leu Gly Lys Leu Gln Lys 
            260                 265                 270         


Gln Pro Ala Val Gly Ile Asn Ser Pro Leu Tyr Leu Gly Gly Ile Pro 
        275                 280                 285             


Thr Ser Thr Gly Leu Ser Ala Leu Arg Gln Gly Thr Asp Arg Pro Leu 
    290                 295                 300                 


Gly Gly Phe His Gly Cys Ile His Glu Val Arg Ile Asn Asn Glu Leu 
305                 310                 315                 320 


Gln Asp Phe Lys Ala Leu Pro Pro Gln Ser Leu Gly Val Ser Pro Gly 
                325                 330                 335     


Cys Lys Ser Cys Thr Val Cys Lys His Gly Leu Cys Arg Ser Val Glu 
            340                 345                 350         


Lys Asp Ser Val Val Cys Glu Cys Arg Pro Gly Trp Thr Gly Pro Leu 
        355                 360                 365             


Cys Asp Gln Glu Ala Arg Asp Pro Cys Leu Gly His Arg Cys His His 
    370                 375                 380                 


Gly Lys Cys Val Ala Thr Gly Thr Ser Tyr Met Cys Lys Cys Ala Glu 
385                 390                 395                 400 


Gly Tyr Gly Gly Asp Leu Cys Asp Asn Lys Asn Asp Ser Ala Asn Ala 
                405                 410                 415     


Cys Ser Ala Phe Lys Cys His His Gly Gln Cys His Ile Ser Asp Gln 
            420                 425                 430         


Gly Glu Pro Tyr Cys Leu Cys Gln Pro Gly Phe Ser Gly Glu His Cys 
        435                 440                 445             


Gln Gln Glu Asn Pro Cys Leu Gly Gln Val Val Arg Glu Val Ile Arg 
    450                 455                 460                 


Arg Gln Lys Gly Tyr Ala Ser Cys Ala Thr Ala Ser Lys Val Pro Ile 
465                 470                 475                 480 


Met Glu Cys Arg Gly Gly Cys Gly Pro Gln Cys Cys Gln Pro Thr Arg 
                485                 490                 495     


Ser Lys Arg Arg Lys Tyr Val Phe Gln Cys Thr Asp Gly Ser Ser Phe 
            500                 505                 510         


Val Glu Glu Val Glu Arg His Leu Glu Cys Gly Cys Leu Ala Cys Ser 
        515                 520                 525             


<210>  1216
<211>  605
<212>  PRT
<213>  Homo Sapiens

<400>  1216

Asn Val Thr Gly Asp Val Cys Lys Glu Lys Ile Cys Ser Cys Asn Glu 
1               5                   10                  15      


Ile Glu Gly Asp Leu His Val Asp Cys Glu Lys Lys Gly Phe Thr Ser 
            20                  25                  30          


Leu Gln Arg Phe Thr Ala Pro Thr Ser Gln Phe Tyr His Leu Phe Leu 
        35                  40                  45              


His Gly Asn Ser Leu Thr Arg Leu Phe Pro Asn Glu Phe Ala Asn Phe 
    50                  55                  60                  


Tyr Asn Ala Val Ser Leu His Met Glu Asn Asn Gly Leu His Glu Ile 
65                  70                  75                  80  


Val Pro Gly Ala Phe Leu Gly Leu Gln Leu Val Lys Arg Leu His Ile 
                85                  90                  95      


Asn Asn Asn Lys Ile Lys Ser Phe Arg Lys Gln Thr Phe Leu Gly Leu 
            100                 105                 110         


Asp Asp Leu Glu Tyr Leu Gln Ala Asp Phe Asn Leu Leu Arg Asp Ile 
        115                 120                 125             


Asp Pro Gly Ala Phe Gln Asp Leu Asn Lys Leu Glu Val Leu Ile Leu 
    130                 135                 140                 


Asn Asp Asn Leu Ile Ser Thr Leu Pro Ala Asn Val Phe Gln Tyr Val 
145                 150                 155                 160 


Pro Ile Thr His Leu Asp Leu Arg Gly Asn Arg Leu Lys Thr Leu Pro 
                165                 170                 175     


Tyr Glu Glu Val Leu Glu Gln Ile Pro Gly Ile Ala Glu Ile Leu Leu 
            180                 185                 190         


Glu Asp Asn Pro Trp Asp Cys Thr Cys Asp Leu Leu Ser Leu Lys Glu 
        195                 200                 205             


Trp Leu Glu Asn Ile Pro Lys Asn Ala Leu Ile Gly Arg Val Val Cys 
    210                 215                 220                 


Glu Ala Pro Thr Arg Leu Gln Gly Lys Asp Leu Asn Glu Thr Thr Glu 
225                 230                 235                 240 


Gln Asp Leu Cys Pro Leu Lys Asn Arg Val Asp Ser Ser Leu Pro Ala 
                245                 250                 255     


Pro Pro Ala Gln Glu Glu Thr Phe Ala Pro Gly Pro Leu Pro Thr Pro 
            260                 265                 270         


Phe Lys Thr Asn Gly Gln Glu Asp His Ala Thr Pro Gly Ser Ala Pro 
        275                 280                 285             


Asn Gly Gly Thr Lys Ile Pro Gly Asn Trp Gln Ile Lys Ile Arg Pro 
    290                 295                 300                 


Thr Ala Ala Ile Ala Thr Gly Ser Ser Arg Asn Lys Pro Leu Ala Asn 
305                 310                 315                 320 


Ser Leu Pro Cys Pro Gly Gly Cys Ser Cys Asp His Ile Pro Gly Ser 
                325                 330                 335     


Gly Leu Lys Met Asn Cys Asn Asn Arg Asn Val Ser Ser Leu Ala Asp 
            340                 345                 350         


Leu Lys Pro Lys Leu Ser Asn Val Gln Glu Leu Phe Leu Arg Asp Asn 
        355                 360                 365             


Lys Ile His Ser Ile Arg Lys Ser His Phe Val Asp Tyr Lys Asn Leu 
    370                 375                 380                 


Ile Leu Leu Asp Leu Gly Asn Asn Asn Ile Ala Thr Val Glu Asn Asn 
385                 390                 395                 400 


Ser Phe Lys Asn Leu Leu Asp Leu Arg Trp Leu Tyr Met Asp Ser Asn 
                405                 410                 415     


Tyr Leu Asp Thr Leu Ser Arg Glu Lys Phe Ala Gly Leu Gln Asn Leu 
            420                 425                 430         


Glu Tyr Leu Asn Val Glu Tyr Asn Ala Ile Gln Leu Ile Leu Pro Gly 
        435                 440                 445             


Thr Phe Asn Ala Met Pro Lys Leu Arg Ile Leu Ile Leu Asn Asn Asn 
    450                 455                 460                 


Leu Leu Arg Ser Leu Pro Val Asp Val Phe Ala Gly Val Ser Leu Ser 
465                 470                 475                 480 


Lys Leu Ser Leu His Asn Asn Tyr Phe Met Tyr Leu Pro Val Ala Gly 
                485                 490                 495     


Val Leu Asp Gln Leu Thr Ser Ile Ile Gln Ile Asp Leu His Gly Asn 
            500                 505                 510         


Pro Trp Glu Cys Ser Cys Thr Ile Val Pro Phe Lys Gln Trp Ala Glu 
        515                 520                 525             


Arg Leu Gly Ser Glu Val Leu Met Ser Asp Leu Lys Cys Glu Thr Pro 
    530                 535                 540                 


Val Asn Phe Phe Arg Lys Asp Phe Met Leu Leu Ser Asn Asp Glu Ile 
545                 550                 555                 560 


Cys Pro Gln Leu Tyr Ala Arg Ile Ser Pro Thr Leu Thr Ser His Ser 
                565                 570                 575     


Lys Asn Ser Thr Gly Leu Ala Glu Thr Gly Thr His Ser Asn Ser Tyr 
            580                 585                 590         


Leu Asp Thr Ser Arg Val Ser Ile Ser Val Leu Val Pro 
        595                 600                 605 


<210>  1217
<211>  600
<212>  PRT
<213>  Homo Sapiens

<400>  1217

Arg Lys Thr Ala Lys Asp Ile Cys Lys Ile Arg Cys Leu Cys Glu Glu 
1               5                   10                  15      


Lys Glu Asn Val Leu Asn Ile Asn Cys Glu Asn Lys Gly Phe Thr Thr 
            20                  25                  30          


Val Ser Leu Leu Gln Pro Pro Gln Tyr Arg Ile Tyr Gln Leu Phe Leu 
        35                  40                  45              


Asn Gly Asn Leu Leu Thr Arg Leu Tyr Pro Asn Glu Phe Val Asn Tyr 
    50                  55                  60                  


Ser Asn Ala Val Thr Leu His Leu Gly Asn Asn Gly Leu Gln Glu Ile 
65                  70                  75                  80  


Arg Thr Gly Ala Phe Ser Gly Leu Lys Thr Leu Lys Arg Leu His Leu 
                85                  90                  95      


Asn Asn Asn Lys Leu Glu Ile Leu Arg Glu Asp Thr Phe Leu Gly Leu 
            100                 105                 110         


Glu Ser Leu Glu Tyr Leu Gln Ala Asp Tyr Asn Tyr Ile Ser Ala Ile 
        115                 120                 125             


Glu Ala Gly Ala Phe Ser Lys Leu Asn Lys Leu Lys Val Leu Ile Leu 
    130                 135                 140                 


Asn Asp Asn Leu Leu Leu Ser Leu Pro Ser Asn Val Phe Arg Phe Val 
145                 150                 155                 160 


Leu Leu Thr His Leu Asp Leu Arg Gly Asn Arg Leu Lys Val Met Pro 
                165                 170                 175     


Phe Ala Gly Val Leu Glu His Ile Gly Gly Ile Met Glu Ile Gln Leu 
            180                 185                 190         


Glu Glu Asn Pro Trp Asn Cys Thr Cys Asp Leu Leu Pro Leu Lys Ala 
        195                 200                 205             


Trp Leu Asp Thr Ile Thr Val Phe Val Gly Glu Ile Val Cys Glu Thr 
    210                 215                 220                 


Pro Phe Arg Leu His Gly Lys Asp Val Thr Gln Leu Thr Arg Gln Asp 
225                 230                 235                 240 


Leu Cys Pro Arg Lys Ser Ala Ser Asp Ser Ser Gln Arg Gly Ser His 
                245                 250                 255     


Ala Asp Thr His Val Gln Arg Leu Ser Pro Thr Met Asn Pro Ala Leu 
            260                 265                 270         


Asn Pro Thr Arg Ala Pro Lys Ala Ser Arg Pro Pro Lys Met Arg Asn 
        275                 280                 285             


Arg Pro Thr Pro Arg Val Thr Val Ser Lys Asp Arg Gln Ser Phe Gly 
    290                 295                 300                 


Pro Ile Met Val Tyr Gln Thr Lys Ser Pro Val Pro Leu Thr Cys Pro 
305                 310                 315                 320 


Ser Ser Cys Val Cys Thr Ser Gln Ser Ser Asp Asn Gly Leu Asn Val 
                325                 330                 335     


Asn Cys Gln Glu Arg Lys Phe Thr Asn Ile Ser Asp Leu Gln Pro Lys 
            340                 345                 350         


Pro Thr Ser Pro Lys Lys Leu Tyr Leu Thr Gly Asn Tyr Leu Gln Thr 
        355                 360                 365             


Val Tyr Lys Asn Asp Leu Leu Glu Tyr Ser Ser Leu Asp Leu Leu His 
    370                 375                 380                 


Leu Gly Asn Asn Arg Ile Ala Val Ile Gln Glu Gly Ala Phe Thr Asn 
385                 390                 395                 400 


Leu Thr Ser Leu Arg Arg Leu Tyr Leu Asn Gly Asn Tyr Leu Glu Val 
                405                 410                 415     


Leu Tyr Pro Ser Met Phe Asp Gly Leu Gln Ser Leu Gln Tyr Leu Tyr 
            420                 425                 430         


Leu Glu Tyr Asn Val Ile Lys Glu Ile Lys Pro Leu Thr Phe Asp Ala 
        435                 440                 445             


Leu Ile Asn Leu Gln Leu Leu Phe Leu Asn Asn Asn Leu Leu Arg Ser 
    450                 455                 460                 


Leu Pro Asp Asn Ile Phe Gly Gly Thr Ala Leu Thr Arg Leu Asn Leu 
465                 470                 475                 480 


Arg Asn Asn His Phe Ser His Leu Pro Val Lys Gly Val Leu Asp Gln 
                485                 490                 495     


Leu Pro Ala Phe Ile Gln Ile Asp Leu Gln Glu Asn Pro Trp Asp Cys 
            500                 505                 510         


Thr Cys Asp Ile Met Gly Leu Lys Asp Trp Thr Glu His Ala Asn Ser 
        515                 520                 525             


Pro Val Ile Ile Asn Glu Val Thr Cys Glu Ser Pro Ala Lys His Ala 
    530                 535                 540                 


Gly Glu Ile Leu Lys Phe Leu Gly Arg Glu Ala Ile Cys Pro Asp Ser 
545                 550                 555                 560 


Pro Asn Leu Ser Asp Gly Thr Val Leu Ser Met Asn His Asn Thr Asp 
                565                 570                 575     


Thr Pro Arg Ser Leu Ser Val Ser Pro Ser Ser Tyr Pro Glu Leu His 
            580                 585                 590         


Thr Glu Val Pro Leu Ser Val Leu 
        595                 600 


<210>  1218
<211>  626
<212>  PRT
<213>  Homo Sapiens

<400>  1218

Thr Pro Ile Pro Leu Ile Glu Asp Ser Glu Glu Ile Asp Glu Pro Cys 
1               5                   10                  15      


Phe Asp Pro Cys Tyr Cys Glu Val Lys Glu Ser Leu Phe His Ile His 
            20                  25                  30          


Cys Asp Ser Lys Gly Phe Thr Asn Ile Ser Gln Ile Thr Glu Phe Trp 
        35                  40                  45              


Ser Arg Pro Phe Lys Leu Tyr Leu Gln Arg Asn Ser Met Arg Lys Leu 
    50                  55                  60                  


Tyr Thr Asn Ser Phe Leu His Leu Asn Asn Ala Val Ser Ile Asn Leu 
65                  70                  75                  80  


Gly Asn Asn Ala Leu Gln Asp Ile Gln Thr Gly Ala Phe Asn Gly Leu 
                85                  90                  95      


Lys Ile Leu Lys Arg Leu Tyr Leu His Glu Asn Lys Leu Asp Val Phe 
            100                 105                 110         


Arg Asn Asp Thr Phe Leu Gly Leu Glu Ser Leu Glu Tyr Leu Gln Ala 
        115                 120                 125             


Asp Tyr Asn Val Ile Lys Arg Ile Glu Ser Gly Ala Phe Arg Asn Leu 
    130                 135                 140                 


Ser Lys Leu Arg Val Leu Ile Leu Asn Asp Asn Leu Ile Pro Met Leu 
145                 150                 155                 160 


Pro Thr Asn Leu Phe Lys Ala Val Ser Leu Thr His Leu Asp Leu Arg 
                165                 170                 175     


Gly Asn Arg Leu Lys Val Leu Phe Tyr Arg Gly Met Leu Asp His Ile 
            180                 185                 190         


Gly Arg Ser Leu Met Glu Leu Gln Leu Glu Glu Asn Pro Trp Asn Cys 
        195                 200                 205             


Thr Cys Glu Ile Val Gln Leu Lys Ser Trp Leu Glu Arg Ile Pro Tyr 
    210                 215                 220                 


Thr Ala Leu Val Gly Asp Ile Thr Cys Glu Thr Pro Phe His Phe His 
225                 230                 235                 240 


Gly Lys Asp Leu Arg Glu Ile Arg Lys Thr Glu Leu Cys Pro Leu Leu 
                245                 250                 255     


Ser Asp Ser Glu Val Glu Ala Ser Leu Gly Ile Pro His Ser Ser Ser 
            260                 265                 270         


Ser Lys Glu Asn Ala Trp Pro Thr Lys Pro Ser Ser Met Leu Ser Ser 
        275                 280                 285             


Val His Phe Thr Ala Ser Ser Val Glu Tyr Lys Ser Ser Asn Lys Gln 
    290                 295                 300                 


Pro Lys Pro Thr Lys Gln Pro Arg Thr Pro Arg Pro Pro Ser Thr Ser 
305                 310                 315                 320 


Gln Ala Leu Tyr Pro Gly Pro Asn Gln Pro Pro Ile Ala Pro Tyr Gln 
                325                 330                 335     


Thr Arg Pro Pro Ile Pro Ile Ile Cys Pro Thr Gly Cys Thr Cys Asn 
            340                 345                 350         


Leu His Ile Asn Asp Leu Gly Leu Thr Val Asn Cys Lys Glu Arg Gly 
        355                 360                 365             


Phe Asn Asn Ile Ser Glu Leu Leu Pro Arg Pro Leu Asn Ala Lys Lys 
    370                 375                 380                 


Leu Tyr Leu Ser Ser Asn Leu Ile Gln Lys Ile Tyr Arg Ser Asp Phe 
385                 390                 395                 400 


Trp Asn Phe Ser Ser Leu Asp Leu Leu His Leu Gly Asn Asn Arg Ile 
                405                 410                 415     


Ser Tyr Val Gln Asp Gly Ala Phe Ile Asn Leu Pro Asn Leu Lys Ser 
            420                 425                 430         


Leu Phe Leu Asn Gly Asn Asp Ile Glu Lys Leu Thr Pro Gly Met Phe 
        435                 440                 445             


Arg Gly Leu Gln Ser Leu His Tyr Leu Tyr Phe Glu Phe Asn Val Ile 
    450                 455                 460                 


Arg Glu Ile Gln Pro Ala Ala Phe Ser Leu Met Pro Asn Leu Lys Leu 
465                 470                 475                 480 


Leu Phe Leu Asn Asn Asn Leu Leu Arg Thr Leu Pro Thr Asp Ala Phe 
                485                 490                 495     


Ala Gly Thr Ser Leu Ala Arg Leu Asn Leu Arg Lys Asn Tyr Phe Leu 
            500                 505                 510         


Tyr Leu Pro Val Ala Gly Val Leu Glu His Leu Asn Ala Ile Val Gln 
        515                 520                 525             


Ile Asp Leu Asn Glu Asn Pro Trp Asp Cys Thr Cys Asp Leu Val Pro 
    530                 535                 540                 


Phe Lys Gln Trp Ile Glu Thr Ile Ser Ser Val Ser Val Val Gly Asp 
545                 550                 555                 560 


Val Leu Cys Arg Ser Pro Glu Asn Leu Thr His Arg Asp Val Arg Thr 
                565                 570                 575     


Ile Glu Leu Glu Val Leu Cys Pro Glu Met Leu His Val Ala Pro Ala 
            580                 585                 590         


Gly Glu Ser Pro Ala Gln Pro Gly Asp Ser His Leu Ile Gly Ala Pro 
        595                 600                 605             


Thr Ser Ala Ser Pro Tyr Glu Phe Ser Pro Pro Gly Gly Pro Val Pro 
    610                 615                 620                 


Leu Ser 
625     


<210>  1219
<211>  600
<212>  PRT
<213>  Homo Sapiens

<400>  1219

Asp Ser Asp Ile Ser Val Glu Ile Cys Asn Val Cys Ser Cys Val Ser 
1               5                   10                  15      


Val Glu Asn Val Leu Tyr Val Asn Cys Glu Lys Val Ser Val Tyr Arg 
            20                  25                  30          


Pro Asn Gln Leu Lys Pro Pro Trp Ser Asn Phe Tyr His Leu Asn Phe 
        35                  40                  45              


Gln Asn Asn Phe Leu Asn Ile Leu Tyr Pro Asn Thr Phe Leu Asn Phe 
    50                  55                  60                  


Ser His Ala Val Ser Leu His Leu Gly Asn Asn Lys Leu Gln Asn Ile 
65                  70                  75                  80  


Glu Gly Gly Ala Phe Leu Gly Leu Ser Ala Leu Lys Gln Leu His Leu 
                85                  90                  95      


Asn Asn Asn Glu Leu Lys Ile Leu Arg Ala Asp Thr Phe Leu Gly Ile 
            100                 105                 110         


Glu Asn Leu Glu Tyr Leu Gln Ala Asp Tyr Asn Leu Ile Lys Tyr Ile 
        115                 120                 125             


Glu Arg Gly Ala Phe Asn Lys Leu His Lys Leu Lys Val Leu Ile Leu 
    130                 135                 140                 


Asn Asp Asn Leu Ile Ser Phe Leu Pro Asp Asn Ile Phe Arg Phe Ala 
145                 150                 155                 160 


Ser Leu Thr His Leu Asp Ile Arg Gly Asn Arg Ile Gln Lys Leu Pro 
                165                 170                 175     


Tyr Ile Gly Val Leu Glu His Ile Gly Arg Val Val Glu Leu Gln Leu 
            180                 185                 190         


Glu Asp Asn Pro Trp Asn Cys Ser Cys Asp Leu Leu Pro Leu Lys Ala 
        195                 200                 205             


Trp Leu Glu Asn Met Pro Tyr Asn Ile Tyr Ile Gly Glu Ala Ile Cys 
    210                 215                 220                 


Glu Thr Pro Ser Asp Leu Tyr Gly Arg Leu Leu Lys Glu Thr Asn Lys 
225                 230                 235                 240 


Gln Glu Leu Cys Pro Met Gly Thr Gly Ser Asp Phe Asp Val Arg Ile 
                245                 250                 255     


Leu Pro Pro Ser Gln Leu Glu Asn Gly Tyr Thr Thr Pro Asn Gly His 
            260                 265                 270         


Thr Thr Gln Thr Ser Leu His Arg Leu Val Thr Lys Pro Pro Lys Thr 
        275                 280                 285             


Thr Asn Pro Ser Lys Ile Ser Gly Ile Val Ala Gly Lys Ala Leu Ser 
    290                 295                 300                 


Asn Arg Asn Leu Ser Gln Ile Val Ser Tyr Gln Thr Arg Val Pro Pro 
305                 310                 315                 320 


Leu Thr Pro Cys Pro Ala Pro Cys Phe Cys Lys Thr His Pro Ser Asp 
                325                 330                 335     


Leu Gly Leu Ser Val Asn Cys Gln Glu Lys Asn Ile Gln Ser Met Ser 
            340                 345                 350         


Glu Leu Ile Pro Lys Pro Leu Asn Ala Lys Lys Leu His Val Asn Gly 
        355                 360                 365             


Asn Ser Ile Lys Asp Val Asp Val Ser Asp Phe Thr Asp Phe Glu Gly 
    370                 375                 380                 


Leu Asp Leu Leu His Leu Gly Ser Asn Gln Ile Thr Val Ile Lys Gly 
385                 390                 395                 400 


Asp Val Phe His Asn Leu Thr Asn Leu Arg Arg Leu Tyr Leu Asn Gly 
                405                 410                 415     


Asn Gln Ile Glu Arg Leu Tyr Pro Glu Ile Phe Ser Gly Leu His Asn 
            420                 425                 430         


Leu Gln Tyr Leu Tyr Leu Glu Tyr Asn Leu Ile Lys Glu Ile Ser Ala 
        435                 440                 445             


Gly Thr Phe Asp Ser Met Pro Asn Leu Gln Leu Leu Tyr Leu Asn Asn 
    450                 455                 460                 


Asn Leu Leu Lys Ser Leu Pro Val Tyr Ile Phe Ser Gly Ala Pro Leu 
465                 470                 475                 480 


Ala Arg Leu Asn Leu Arg Asn Asn Lys Phe Met Tyr Leu Pro Val Ser 
                485                 490                 495     


Gly Val Leu Asp Gln Leu Gln Ser Leu Thr Gln Ile Asp Leu Glu Gly 
            500                 505                 510         


Asn Pro Trp Asp Cys Thr Cys Asp Leu Val Ala Leu Lys Leu Trp Val 
        515                 520                 525             


Glu Lys Leu Ser Asp Gly Ile Val Val Lys Glu Leu Lys Cys Glu Thr 
    530                 535                 540                 


Pro Val Gln Phe Ala Asn Ile Glu Leu Lys Ser Leu Lys Asn Glu Ile 
545                 550                 555                 560 


Leu Cys Pro Lys Leu Leu Asn Lys Pro Ser Ala Pro Phe Thr Ser Pro 
                565                 570                 575     


Ala Pro Ala Ile Thr Phe Thr Thr Pro Leu Gly Pro Ile Arg Ser Pro 
            580                 585                 590         


Pro Gly Gly Pro Val Pro Leu Ser 
        595                 600 


<210>  1220
<211>  624
<212>  PRT
<213>  Homo Sapiens

<400>  1220

Ile Asp Tyr Tyr Gly Glu Ile Cys Asp Asn Ala Cys Pro Cys Glu Glu 
1               5                   10                  15      


Lys Asp Gly Ile Leu Thr Val Ser Cys Glu Asn Arg Gly Ile Ile Ser 
            20                  25                  30          


Leu Ser Glu Ile Ser Pro Pro Arg Phe Pro Ile Tyr His Leu Leu Leu 
        35                  40                  45              


Ser Gly Asn Leu Leu Asn Arg Leu Tyr Pro Asn Glu Phe Val Asn Tyr 
    50                  55                  60                  


Thr Gly Ala Ser Ile Leu His Leu Gly Ser Asn Val Ile Gln Asp Ile 
65                  70                  75                  80  


Glu Thr Gly Ala Phe His Gly Leu Arg Gly Leu Arg Arg Leu His Leu 
                85                  90                  95      


Asn Asn Asn Lys Leu Glu Leu Leu Arg Asp Asp Thr Phe Leu Gly Leu 
            100                 105                 110         


Glu Asn Leu Glu Tyr Leu Gln Val Asp Tyr Asn Tyr Ile Ser Val Ile 
        115                 120                 125             


Glu Pro Asn Ala Phe Gly Lys Leu His Leu Leu Gln Val Leu Ile Leu 
    130                 135                 140                 


Asn Asp Asn Leu Leu Ser Ser Leu Pro Asn Asn Leu Phe Arg Phe Val 
145                 150                 155                 160 


Pro Leu Thr His Leu Asp Leu Arg Gly Asn Arg Leu Lys Leu Leu Pro 
                165                 170                 175     


Tyr Val Gly Leu Leu Gln His Met Asp Lys Val Val Glu Leu Gln Leu 
            180                 185                 190         


Glu Glu Asn Pro Trp Asn Cys Ser Cys Glu Leu Ile Ser Leu Lys Asp 
        195                 200                 205             


Trp Leu Asp Ser Ile Ser Tyr Ser Ala Leu Val Gly Asp Val Val Cys 
    210                 215                 220                 


Glu Thr Pro Phe Arg Leu His Gly Arg Asp Leu Asp Glu Val Ser Lys 
225                 230                 235                 240 


Gln Glu Leu Cys Pro Arg Arg Leu Ile Ser Asp Tyr Glu Met Arg Pro 
                245                 250                 255     


Gln Thr Pro Leu Ser Thr Thr Gly Tyr Leu His Thr Thr Pro Ala Ser 
            260                 265                 270         


Val Asn Ser Val Ala Thr Ser Ser Ser Ala Val Tyr Lys Pro Pro Leu 
        275                 280                 285             


Lys Pro Pro Lys Gly Thr Arg Gln Pro Asn Lys Pro Arg Val Arg Pro 
    290                 295                 300                 


Thr Ser Arg Gln Pro Ser Lys Asp Leu Gly Tyr Ser Asn Tyr Gly Pro 
305                 310                 315                 320 


Ser Ile Ala Tyr Gln Thr Lys Ser Pro Val Pro Leu Glu Cys Pro Thr 
                325                 330                 335     


Ala Cys Ser Cys Asn Leu Gln Ile Ser Asp Leu Gly Leu Asn Val Asn 
            340                 345                 350         


Cys Gln Glu Arg Lys Ile Glu Ser Ile Ala Glu Leu Gln Pro Lys Pro 
        355                 360                 365             


Tyr Asn Pro Lys Lys Met Tyr Leu Thr Glu Asn Tyr Ile Ala Val Val 
    370                 375                 380                 


Arg Arg Thr Asp Phe Leu Glu Ala Thr Gly Leu Asp Leu Leu His Leu 
385                 390                 395                 400 


Gly Asn Asn Arg Ile Ser Met Ile Gln Asp Arg Ala Phe Gly Asp Leu 
                405                 410                 415     


Thr Asn Leu Arg Arg Leu Tyr Leu Asn Gly Asn Arg Ile Glu Arg Leu 
            420                 425                 430         


Ser Pro Glu Leu Phe Tyr Gly Leu Gln Ser Leu Gln Tyr Leu Phe Leu 
        435                 440                 445             


Gln Tyr Asn Leu Ile Arg Glu Ile Gln Ser Gly Thr Phe Asp Pro Val 
    450                 455                 460                 


Pro Asn Leu Gln Leu Leu Phe Leu Asn Asn Asn Leu Leu Gln Ala Met 
465                 470                 475                 480 


Pro Ser Gly Val Phe Ser Gly Leu Thr Leu Leu Arg Leu Asn Leu Arg 
                485                 490                 495     


Ser Asn His Phe Thr Ser Leu Pro Val Ser Gly Val Leu Asp Gln Leu 
            500                 505                 510         


Lys Ser Leu Ile Gln Ile Asp Leu His Asp Asn Pro Trp Asp Cys Thr 
        515                 520                 525             


Cys Asp Ile Val Gly Met Lys Leu Trp Val Glu Gln Leu Lys Val Gly 
    530                 535                 540                 


Val Leu Val Asp Glu Val Ile Cys Lys Ala Pro Lys Lys Phe Ala Glu 
545                 550                 555                 560 


Thr Asp Met Arg Ser Ile Lys Ser Glu Leu Leu Cys Pro Asp Tyr Ser 
                565                 570                 575     


Asp Val Val Val Ser Thr Pro Thr Pro Ser Ser Ile Gln Val Pro Ala 
            580                 585                 590         


Arg Thr Ser Ala Val Thr Pro Ala Val Arg Leu Asn Ser Thr Gly Ala 
        595                 600                 605             


Pro Ala Ser Leu Gly Ala Gly Gly Gly Ala Ser Ser Val Pro Leu Ser 
    610                 615                 620                 


<210>  1221
<211>  582
<212>  PRT
<213>  Homo Sapiens

<400>  1221

Ser Arg Gly Ser Cys Asp Ser Leu Cys Asn Cys Glu Glu Lys Asp Gly 
1               5                   10                  15      


Thr Met Leu Ile Asn Cys Glu Ala Lys Gly Ile Lys Met Val Ser Glu 
            20                  25                  30          


Ile Ser Val Pro Pro Ser Arg Pro Phe Gln Leu Ser Leu Leu Asn Asn 
        35                  40                  45              


Gly Leu Thr Met Leu His Thr Asn Asp Phe Ser Gly Leu Thr Asn Ala 
    50                  55                  60                  


Ile Ser Ile His Leu Gly Phe Asn Asn Ile Ala Asp Ile Glu Ile Gly 
65                  70                  75                  80  


Ala Phe Asn Gly Leu Gly Leu Leu Lys Gln Leu His Ile Asn His Asn 
                85                  90                  95      


Ser Leu Glu Ile Leu Lys Glu Asp Thr Phe His Gly Leu Glu Asn Leu 
            100                 105                 110         


Glu Phe Leu Gln Ala Asp Asn Asn Phe Ile Thr Val Ile Glu Pro Ser 
        115                 120                 125             


Ala Phe Ser Lys Leu Asn Arg Leu Lys Val Leu Ile Leu Asn Asp Asn 
    130                 135                 140                 


Ala Ile Glu Ser Leu Pro Pro Asn Ile Phe Arg Phe Val Pro Leu Thr 
145                 150                 155                 160 


His Leu Asp Leu Arg Gly Asn Gln Leu Gln Thr Leu Pro Tyr Val Gly 
                165                 170                 175     


Phe Leu Glu His Ile Gly Arg Ile Leu Asp Leu Gln Leu Glu Asp Asn 
            180                 185                 190         


Lys Trp Ala Cys Asn Cys Asp Leu Leu Gln Leu Lys Thr Trp Leu Glu 
        195                 200                 205             


Asn Met Pro Pro Gln Ser Ile Ile Gly Asp Val Val Cys Asn Ser Pro 
    210                 215                 220                 


Pro Phe Phe Lys Gly Ser Ile Leu Ser Arg Leu Lys Lys Glu Ser Ile 
225                 230                 235                 240 


Cys Pro Thr Pro Pro Val Tyr Glu Glu His Glu Asp Pro Ser Gly Ser 
                245                 250                 255     


Leu His Leu Ala Ala Thr Ser Ser Ile Asn Asp Ser Arg Met Ser Thr 
            260                 265                 270         


Lys Thr Thr Ser Ile Leu Lys Leu Pro Thr Lys Ala Pro Gly Leu Ile 
        275                 280                 285             


Pro Tyr Ile Thr Lys Pro Ser Thr Gln Leu Pro Gly Pro Tyr Cys Pro 
    290                 295                 300                 


Ile Pro Cys Asn Cys Lys Val Leu Ser Pro Ser Gly Leu Leu Ile His 
305                 310                 315                 320 


Cys Gln Glu Arg Asn Ile Glu Ser Leu Ser Asp Leu Arg Pro Pro Pro 
                325                 330                 335     


Gln Asn Pro Arg Lys Leu Ile Leu Ala Gly Asn Ile Ile His Ser Leu 
            340                 345                 350         


Met Lys Ser Asp Leu Val Glu Tyr Phe Thr Leu Glu Met Leu His Leu 
        355                 360                 365             


Gly Asn Asn Arg Ile Glu Val Leu Glu Glu Gly Ser Phe Met Asn Leu 
    370                 375                 380                 


Thr Arg Leu Gln Lys Leu Tyr Leu Asn Gly Asn His Leu Thr Lys Leu 
385                 390                 395                 400 


Ser Lys Gly Met Phe Leu Gly Leu His Asn Leu Glu Tyr Leu Tyr Leu 
                405                 410                 415     


Glu Tyr Asn Ala Ile Lys Glu Ile Leu Pro Gly Thr Phe Asn Pro Met 
            420                 425                 430         


Pro Lys Leu Lys Val Leu Tyr Leu Asn Asn Asn Leu Leu Gln Val Leu 
        435                 440                 445             


Pro Pro His Ile Phe Ser Gly Val Pro Leu Thr Lys Val Asn Leu Lys 
    450                 455                 460                 


Thr Asn Gln Phe Thr His Leu Pro Val Ser Asn Ile Leu Asp Asp Leu 
465                 470                 475                 480 


Asp Leu Leu Thr Gln Ile Asp Leu Glu Asp Asn Pro Trp Asp Cys Ser 
                485                 490                 495     


Cys Asp Leu Val Gly Leu Gln Gln Trp Ile Gln Lys Leu Ser Lys Asn 
            500                 505                 510         


Thr Val Thr Asp Asp Ile Leu Cys Thr Ser Pro Gly His Leu Asp Lys 
        515                 520                 525             


Lys Glu Leu Lys Ala Leu Asn Ser Glu Ile Leu Cys Pro Gly Leu Val 
    530                 535                 540                 


Asn Asn Pro Ser Met Pro Thr Gln Thr Ser Tyr Leu Met Val Thr Thr 
545                 550                 555                 560 


Pro Ala Thr Thr Thr Asn Thr Ala Asp Thr Ile Leu Arg Ser Leu Thr 
                565                 570                 575     


Asp Ala Val Pro Leu Ser 
            580         


<210>  1222
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  1222

Leu Lys Cys Tyr Thr Cys Lys Glu Pro Met Thr Ser Ala Ser Cys Arg 
1               5                   10                  15      


Thr Ile Thr Arg Cys Lys Pro Glu Asp Thr Ala Cys Met Thr Thr Leu 
            20                  25                  30          


Val Thr Val Glu Ala Glu Tyr Pro Phe Asn Gln Ser Pro Val Val Thr 
        35                  40                  45              


Arg Ser Cys Ser Ser Ser Cys Val Ala Thr Asp Pro Asp Ser Ile Gly 
    50                  55                  60                  


Ala Ala His Leu Ile Phe Cys Cys Phe Arg Asp Leu Cys Asn Ser Glu 
65                  70                  75                  80  


Leu 
    


<210>  1223
<211>  600
<212>  PRT
<213>  Homo Sapiens

<400>  1223

Met His Gly Ile Leu Gly Ala Cys Gly Arg Leu Arg Leu Glu Pro Ala 
1               5                   10                  15      


Thr Pro Leu Thr Pro Leu Leu Cys Ala Glu Arg Asp Glu Cys Arg Ala 
            20                  25                  30          


His Pro Cys Arg Asn Gly Gly Ser Cys Arg Asn Leu Pro Gly Ala Tyr 
        35                  40                  45              


Val Cys Arg Cys Pro Ala Gly Phe Val Gly Val His Cys Glu Thr Glu 
    50                  55                  60                  


Val Asp Ala Cys Asp Ser Ser Pro Cys Gln His Gly Gly Arg Cys Glu 
65                  70                  75                  80  


Ser Gly Gly Gly Ala Tyr Leu Cys Val Cys Pro Glu Ser Phe Phe Gly 
                85                  90                  95      


Tyr His Cys Glu Thr Val Ser Asp Pro Cys Phe Ser Ser Pro Cys Gly 
            100                 105                 110         


Gly Arg Gly Tyr Cys Leu Ala Ser Asn Gly Ser His Ser Cys Thr Cys 
        115                 120                 125             


Lys Val Gly Tyr Thr Gly Glu Asp Cys Ala Lys Glu Leu Phe Pro Pro 
    130                 135                 140                 


Thr Ala Leu Lys Met Glu Arg Val Glu Glu Ser Gly Val Ser Ile Ser 
145                 150                 155                 160 


Trp Asn Pro Pro Asn Gly Pro Ala Ala Arg Gln Met Leu Asp Gly Tyr 
                165                 170                 175     


Ala Val Thr Tyr Val Ser Ser Asp Gly Ser Tyr Arg Arg Thr Asp Phe 
            180                 185                 190         


Val Asp Arg Thr Arg Ser Ser His Gln Leu Gln Ala Leu Ala Ala Gly 
        195                 200                 205             


Arg Ala Tyr Asn Ile Ser Val Phe Ser Val Lys Arg Asn Ser Asn Asn 
    210                 215                 220                 


Lys Asn Asp Ile Ser Arg Pro Ala Val Leu Leu Ala Arg Thr Arg Pro 
225                 230                 235                 240 


Arg Pro Val Glu Gly Phe Glu Val Thr Asn Val Thr Ala Ser Thr Ile 
                245                 250                 255     


Ser Val Gln Trp Ala Leu His Arg Ile Arg His Ala Thr Val Ser Gly 
            260                 265                 270         


Val Arg Val Ser Ile Arg His Pro Glu Ala Leu Arg Asp Gln Ala Thr 
        275                 280                 285             


Asp Val Asp Arg Ser Val Asp Arg Phe Thr Phe Arg Ala Leu Leu Pro 
    290                 295                 300                 


Gly Lys Arg Tyr Thr Ile Gln Leu Thr Thr Leu Ser Gly Leu Arg Gly 
305                 310                 315                 320 


Glu Glu His Pro Thr Glu Ser Leu Ala Thr Ala Pro Thr His Val Trp 
                325                 330                 335     


Thr Arg Pro Leu Pro Pro Ala Asn Leu Thr Ala Ala Arg Val Thr Ala 
            340                 345                 350         


Thr Ser Ala His Val Val Trp Asp Ala Pro Thr Pro Gly Ser Leu Leu 
        355                 360                 365             


Glu Ala Tyr Val Ile Asn Val Thr Thr Ser Gln Ser Thr Lys Ser Arg 
    370                 375                 380                 


Tyr Val Pro Asn Gly Lys Leu Ala Ser Tyr Thr Val Arg Asp Leu Leu 
385                 390                 395                 400 


Pro Gly Arg Arg Tyr Gln Leu Ser Val Ile Ala Val Gln Ser Thr Glu 
                405                 410                 415     


Leu Gly Pro Gln His Ser Glu Pro Ala His Leu Tyr Ile Ile Thr Ser 
            420                 425                 430         


Pro Arg Asp Gly Ala Asp Arg Arg Trp His Gln Gly Gly His His Pro 
        435                 440                 445             


Arg Val Leu Lys Asn Arg Pro Pro Pro Ala Arg Leu Pro Glu Leu Arg 
    450                 455                 460                 


Leu Leu Asn Asp His Ser Ala Pro Glu Thr Pro Thr Gln Pro Pro Arg 
465                 470                 475                 480 


Phe Ser Glu Leu Val Asp Gly Arg Gly Arg Val Ser Ala Arg Phe Gly 
                485                 490                 495     


Gly Ser Pro Ser Lys Ala Ala Thr Val Arg Ser His Val Pro Gly Asn 
            500                 505                 510         


Cys Ser Glu Asn Pro Cys Gln Asn Gly Gly Thr Cys Val Pro Gly Ala 
        515                 520                 525             


Asp Ala His Ser Cys Asp Cys Gly Pro Gly Phe Lys Gly Arg Arg Cys 
    530                 535                 540                 


Glu Leu Ala Cys Ile Lys Val Ser Arg Pro Cys Thr Arg Leu Phe Ser 
545                 550                 555                 560 


Glu Thr Lys Ser Phe Pro Val Trp Glu Gly Gly Val Cys His His Val 
                565                 570                 575     


Tyr Lys Arg Val Tyr Arg Val His Gln Asp Ile Cys Phe Lys Glu Ser 
            580                 585                 590         


Cys Glu Ser Thr Ser Leu Lys Leu 
        595                 600 


<210>  1224
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  1224

Val Lys Asp Cys Val Phe Cys Glu Leu Thr Asp Ser Met Gln Cys Pro 
1               5                   10                  15      


Gly Thr Tyr Met His Cys Gly Asp Asp Glu Asp Cys Phe Thr Gly His 
            20                  25                  30          


Gly Val Ala Pro Gly Thr Gly Pro Val Ile Asn Lys Gly Cys Leu Arg 
        35                  40                  45              


Ala Thr Ser Cys Gly Leu Glu Glu Pro Val Ser Tyr Arg Gly Val Thr 
    50                  55                  60                  


Tyr Ser Leu Thr Thr Asn Cys Cys Thr Gly Arg Leu Cys Asn 
65                  70                  75              


<210>  1225
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  1225

Cys Leu Leu Cys Phe Thr Thr Tyr Ser Glu Arg Leu Arg Ile Cys Gln 
1               5                   10                  15      


Met Phe Val Gly Met Arg Ser Pro Lys Leu Glu Glu Cys Glu Glu Ala 
            20                  25                  30          


Phe Thr Ala Ala Phe Gln Gly Leu Ser Asp Thr Glu Ile Ser Glu Glu 
        35                  40                  45              


Thr Ile His Thr Ser Ser Val Ser Trp Gly Arg Cys Arg Gly Arg Ala 
    50                  55                  60                  


Gly Glu Ala Gln Arg Val Arg Leu Arg Asp Arg Gln Arg Glu Thr Val 
65                  70                  75                  80  


Arg Gly Glu Arg Leu Lys Asp His Glu Asn Asn Arg Asp Leu Gly Thr 
                85                  90                  95      


Glu Arg His Arg Gln Gly Lys Thr Ala Gly Gln Arg Leu Arg Glu Gly 
            100                 105                 110         


Arg Met Glu Ser Gln Arg Gly Glu Asp Gly Asp Ser Glu Arg Gly Arg 
        115                 120                 125             


Met Glu Thr Gln Arg Glu Arg Lys Met Glu Thr Arg Lys Asp Gly Asp 
    130                 135                 140                 


Ser Gly Val Trp Arg Val Arg Glu Gly Arg Met Asp Thr Arg Glu Asp 
145                 150                 155                 160 


Gly Glu Ser Gly Gly Trp Arg Leu Ile Glu Arg Gly Gly Trp Arg Val 
                165                 170                 175     


Arg Arg Gly Trp Arg Leu Glu Arg Glu 
            180                 185 


<210>  1226
<211>  478
<212>  PRT
<213>  Homo Sapiens

<400>  1226

Gly Pro Pro Pro Ala Pro Pro Gly Leu Pro Ala Gly Ala Asp Cys Leu 
1               5                   10                  15      


Asn Ser Phe Thr Ala Gly Val Pro Gly Phe Val Leu Asp Thr Asn Ala 
            20                  25                  30          


Ser Val Ser Asn Gly Ala Thr Phe Leu Glu Ser Pro Thr Val Arg Arg 
        35                  40                  45              


Gly Trp Asp Cys Val Arg Ala Cys Cys Thr Thr Gln Asn Cys Asn Leu 
    50                  55                  60                  


Ala Leu Val Glu Leu Gln Pro Asp Arg Gly Glu Asp Ala Ile Ala Ala 
65                  70                  75                  80  


Cys Phe Leu Ile Asn Cys Leu Tyr Glu Gln Asn Phe Val Cys Lys Phe 
                85                  90                  95      


Ala Pro Arg Glu Gly Phe Ile Asn Tyr Leu Thr Arg Glu Val Tyr Arg 
            100                 105                 110         


Ser Tyr Arg Gln Leu Arg Thr Gln Gly Phe Gly Gly Ser Gly Ile Pro 
        115                 120                 125             


Lys Ala Trp Ala Gly Ile Asp Leu Lys Val Gln Pro Gln Glu Pro Leu 
    130                 135                 140                 


Val Leu Lys Asp Val Glu Asn Thr Asp Trp Arg Leu Leu Arg Gly Asp 
145                 150                 155                 160 


Thr Asp Val Arg Val Glu Arg Lys Asp Pro Asn Gln Val Glu Leu Trp 
                165                 170                 175     


Gly Leu Lys Glu Gly Thr Tyr Leu Phe Gln Leu Thr Val Thr Ser Ser 
            180                 185                 190         


Asp His Pro Glu Asp Thr Ala Asn Val Thr Val Thr Val Leu Ser Thr 
        195                 200                 205             


Lys Gln Thr Glu Asp Tyr Cys Leu Ala Ser Asn Lys Val Gly Arg Cys 
    210                 215                 220                 


Arg Gly Ser Phe Pro Arg Trp Tyr Tyr Asp Pro Thr Glu Gln Ile Cys 
225                 230                 235                 240 


Lys Ser Phe Val Tyr Gly Gly Cys Leu Gly Asn Lys Asn Asn Tyr Leu 
                245                 250                 255     


Arg Glu Glu Glu Cys Ile Leu Ala Cys Arg Gly Val Gln Gly Pro Ser 
            260                 265                 270         


Met Glu Arg Arg His Pro Val Cys Ser Gly Thr Cys Gln Pro Thr Gln 
        275                 280                 285             


Phe Arg Cys Ser Asn Gly Cys Cys Ile Asp Ser Phe Leu Glu Cys Asp 
    290                 295                 300                 


Asp Thr Pro Asn Cys Pro Asp Ala Ser Asp Glu Ala Ala Cys Glu Lys 
305                 310                 315                 320 


Tyr Thr Ser Gly Phe Asp Glu Leu Gln Arg Ile His Phe Pro Ser Asp 
                325                 330                 335     


Lys Gly His Cys Val Asp Leu Pro Asp Thr Gly Leu Cys Lys Glu Ser 
            340                 345                 350         


Ile Pro Arg Trp Tyr Tyr Asn Pro Phe Ser Glu His Cys Ala Arg Phe 
        355                 360                 365             


Thr Tyr Gly Gly Cys Tyr Gly Asn Lys Asn Asn Phe Glu Glu Glu Gln 
    370                 375                 380                 


Gln Cys Leu Glu Ser Cys Arg Gly Ile Ser Lys Lys Asp Val Phe Gly 
385                 390                 395                 400 


Leu Arg Arg Glu Ile Pro Ile Pro Ser Thr Gly Ser Val Glu Met Ala 
                405                 410                 415     


Val Ala Val Phe Leu Val Ile Cys Ile Val Val Val Val Ala Ile Leu 
            420                 425                 430         


Gly Tyr Cys Phe Phe Lys Asn Gln Arg Lys Asp Phe His Gly His His 
        435                 440                 445             


His His Pro Pro Pro Thr Pro Ala Ser Ser Thr Val Ser Thr Thr Glu 
    450                 455                 460                 


Asp Thr Glu His Leu Val Tyr Asn His Thr Thr Arg Pro Leu 
465                 470                 475             


<210>  1227
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  1227

Phe Pro Gly Ser Gly Asp Ser Pro Leu Glu Asp Asp Glu Val Gly Tyr 
1               5                   10                  15      


Ser His Pro Arg Tyr Lys Asp Thr Pro Trp Cys Ser Pro Ile Lys Val 
            20                  25                  30          


Lys Tyr Gly Asp Val Tyr Cys Arg Ala Pro Gln Gly Gly Tyr Tyr Lys 
        35                  40                  45              


Thr Ala Leu Gly Thr Arg Cys Asp Ile Arg Cys Gln Lys Gly Tyr Glu 
    50                  55                  60                  


Leu His Gly Ser Ser Leu Leu Ile Cys Gln Ser Asn Lys Arg Trp Ser 
65                  70                  75                  80  


Asp Lys Val Ile Cys Lys Gln Lys Arg Cys Pro Thr Leu Ala Met Pro 
                85                  90                  95      


Ala Asn Gly Gly Phe Lys Cys Val Asp Gly Ala Tyr Phe Asn Ser Arg 
            100                 105                 110         


Cys Glu Tyr Tyr Cys Ser Pro Gly Tyr Thr Leu Lys Gly Glu Arg Thr 
        115                 120                 125             


Val Thr Cys Met Asp Asn Lys Ala Trp Ser Gly Arg Pro Ala Ser Cys 
    130                 135                 140                 


Val Asp Met Glu Pro Pro Arg Ile Lys Cys Pro Ser Val Lys Glu Arg 
145                 150                 155                 160 


Ile Ala Glu Pro Asn Lys Leu Thr Val Arg Val Ser Trp Glu Thr Pro 
                165                 170                 175     


Glu Gly Arg Asp Thr Ala Asp Gly Ile Leu Thr Asp Val Ile Leu Lys 
            180                 185                 190         


Gly Leu Pro Pro Gly Ser Asn Phe Pro Glu Gly Asp His Lys Ile Gln 
        195                 200                 205             


Tyr Thr Val Tyr Asp Arg Ala Glu Asn Lys Gly Thr Cys Lys Phe Arg 
    210                 215                 220                 


Val Lys Val Arg Val Lys Arg Cys Gly Lys Leu Asn Ala Pro Glu Asn 
225                 230                 235                 240 


Gly Tyr Met Lys Cys Ser Ser Asp Gly Asp Asn Tyr Gly Ala Thr Cys 
                245                 250                 255     


Glu Phe Ser Cys Ile Gly Gly Tyr Glu Leu Gln Gly Ser Pro Ala Arg 
            260                 265                 270         


Val Cys Gln Ser Asn Leu Ala Trp Ser Gly Thr Glu Pro Thr Cys Ala 
        275                 280                 285             


Ala Met Asn Val Asn Val Gly Val Arg Thr Ala Ala Ala Leu Leu Asp 
    290                 295                 300                 


Gln Phe Tyr Glu Lys Arg Arg Leu Leu Ile Val Ser Thr Pro Thr Ala 
305                 310                 315                 320 


Arg Asn Leu Leu Tyr Arg Leu Gln Leu Gly Met Leu Gln Gln Ala Gln 
                325                 330                 335     


Cys Gly Leu Asp Leu Arg His Ile Thr Val Val Glu Leu Val Gly Val 
            340                 345                 350         


Phe Pro Thr Leu Ile Gly Arg Ile Gly Ala Lys Ile Met Pro Pro Ala 
        355                 360                 365             


Leu Ala Leu Gln Leu Arg Leu Leu Leu Arg Ile Pro Leu Tyr Ser Phe 
    370                 375                 380                 


Ser Met Val Leu Val Asp Lys His Gly Met Asp Lys Glu Arg Tyr Val 
385                 390                 395                 400 


Ser Leu Val Met Pro Val Ala Leu Phe Asn Leu Ile Asp Thr Phe Pro 
                405                 410                 415     


Leu Arg Lys Glu Glu Met Val Leu Gln Ala Glu Met Ser Gln Thr Cys 
            420                 425                 430         


Asn Thr 
        


<210>  1228
<211>  442
<212>  PRT
<213>  Homo Sapiens

<400>  1228

Thr Trp Tyr Ala Gly Ser Gly Tyr Tyr Pro Asp Glu Ser Tyr Asn Glu 
1               5                   10                  15      


Val Tyr Ala Glu Glu Val Pro Gln Ala Pro Ala Leu Asp Tyr Arg Val 
            20                  25                  30          


Pro Arg Trp Cys Tyr Thr Leu Asn Ile Gln Asp Gly Glu Ala Thr Cys 
        35                  40                  45              


Tyr Ser Pro Lys Gly Gly Asn Tyr His Ser Ser Leu Gly Thr Arg Cys 
    50                  55                  60                  


Glu Leu Ser Cys Asp Arg Gly Phe Arg Leu Ile Gly Arg Arg Ser Val 
65                  70                  75                  80  


Gln Cys Leu Pro Ser Arg Arg Trp Ser Gly Thr Ala Tyr Cys Arg Gln 
                85                  90                  95      


Met Arg Cys His Ala Leu Pro Phe Ile Thr Ser Gly Thr Tyr Thr Cys 
            100                 105                 110         


Thr Asn Gly Val Leu Leu Asp Ser Arg Cys Asp Tyr Ser Cys Ser Ser 
        115                 120                 125             


Gly Tyr His Leu Glu Gly Asp Arg Ser Arg Ile Cys Met Glu Asp Gly 
    130                 135                 140                 


Arg Trp Ser Gly Gly Glu Pro Val Cys Val Asp Ile Asp Pro Pro Lys 
145                 150                 155                 160 


Ile Arg Cys Pro His Ser Arg Glu Lys Met Ala Glu Pro Glu Lys Leu 
                165                 170                 175     


Thr Ala Arg Val Tyr Trp Asp Pro Pro Leu Val Lys Asp Ser Ala Asp 
            180                 185                 190         


Gly Thr Ile Thr Arg Val Thr Leu Arg Gly Pro Glu Pro Gly Ser His 
        195                 200                 205             


Phe Pro Glu Gly Glu His Val Ile Arg Tyr Thr Ala Tyr Asp Arg Ala 
    210                 215                 220                 


Tyr Asn Arg Ala Ser Cys Lys Phe Ile Val Lys Val Gln Val Arg Arg 
225                 230                 235                 240 


Cys Pro Thr Leu Lys Pro Pro Gln His Gly Tyr Leu Thr Cys Thr Ser 
                245                 250                 255     


Ala Gly Asp Asn Tyr Gly Ala Thr Cys Glu Tyr His Cys Asp Gly Gly 
            260                 265                 270         


Tyr Asp Arg Gln Gly Thr Pro Ser Arg Val Cys Gln Ser Ser Arg Gln 
        275                 280                 285             


Trp Ser Gly Ser Pro Pro Ile Cys Ala Pro Met Lys Ile Asn Val Asn 
    290                 295                 300                 


Val Asn Ser Ala Ala Gly Leu Leu Asp Gln Phe Tyr Glu Lys Gln Arg 
305                 310                 315                 320 


Leu Leu Ile Ile Ser Ala Pro Asp Pro Ser Asn Arg Tyr Tyr Lys Met 
                325                 330                 335     


Gln Ile Ser Met Leu Gln Gln Ser Thr Cys Gly Leu Asp Leu Arg His 
            340                 345                 350         


Val Thr Ile Ile Glu Leu Val Gly Gln Pro Pro Gln Glu Val Gly Arg 
        355                 360                 365             


Ile Arg Glu Gln Gln Leu Ser Ala Asn Ile Ile Glu Glu Leu Arg Gln 
    370                 375                 380                 


Phe Gln Arg Leu Thr Arg Ser Tyr Phe Asn Met Val Leu Ile Asp Lys 
385                 390                 395                 400 


Gln Gly Ile Asp Arg Asp Arg Tyr Met Glu Pro Val Thr Pro Glu Glu 
                405                 410                 415     


Ile Phe Thr Phe Ile Asp Asp Tyr Leu Leu Ser Asn Gln Glu Leu Thr 
            420                 425                 430         


Gln Arg Arg Glu Gln Arg Asp Ile Cys Glu 
        435                 440         


<210>  1229
<211>  190
<212>  PRT
<213>  Homo Sapiens

<400>  1229

Met Thr Gly Thr Leu Arg Thr Arg Ala Trp Pro Ala Ala Lys Arg Ala 
1               5                   10                  15      


Ala Gly Leu Arg Trp Ala Leu Arg Asp Glu Ala Arg Leu Ser Asp Cys 
            20                  25                  30          


Phe His Leu Gly Trp Gly Gln His Asn Cys Gly His His Glu Asp Ala 
        35                  40                  45              


Gly Ala Leu Cys Ala Gly Glu Ala Asp Ser Glu Gly Pro Glu Glu Leu 
    50                  55                  60                  


Gly Leu Gln Val Gln Gln Asp Gly Ser Glu Thr Thr Arg Val Pro Thr 
65                  70                  75                  80  


Pro Arg Pro Arg Asp Gly His Leu Arg Leu Val Asn Gly Ala His Arg 
                85                  90                  95      


Cys Glu Gly Arg Val Glu Leu Tyr Leu Gly Gln Arg Trp Gly Thr Val 
            100                 105                 110         


Cys Asp Asp Ala Trp Asp Leu Arg Ala Ala Gly Val Leu Cys Arg Gln 
        115                 120                 125             


Leu Gly Cys Gly Gln Ala Leu Ala Ala Pro Gly Glu Ala His Phe Gly 
    130                 135                 140                 


Pro Gly Arg Gly Pro Ile Leu Leu Asp Asn Val Lys Cys Arg Gly Glu 
145                 150                 155                 160 


Glu Ser Ala Leu Leu Leu Cys Ser His Ile Arg Trp Asp Ala His Asn 
                165                 170                 175     


Cys Asp His Ser Glu Asp Ala Ser Val Leu Cys Gln Pro Ser 
            180                 185                 190 


<210>  1230
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  1230

Leu Ser His Ser His Ser Glu Lys Ala Thr Gly Thr Ser Ser Gly Ala 
1               5                   10                  15      


Asn Ser Glu Glu Ser Thr Ala Ala Glu Phe Cys Arg Ile Asp Lys Pro 
            20                  25                  30          


Leu Cys His Ser Glu Asp Glu Lys Leu Ser Phe Glu Ala Val Arg Asn 
        35                  40                  45              


Ile His Lys Leu Met Asp Asp Asp Ala Asn Gly Asp Val Asp Val Glu 
    50                  55                  60                  


Glu Ser Asp Glu Phe Leu Arg Glu Asp Leu Asn Tyr His Asp Pro Thr 
65                  70                  75                  80  


Val Lys His Ser Thr Phe His Gly Glu Asp Lys Leu Ile Ser Val Glu 
                85                  90                  95      


Asp Leu Trp Lys Ala Trp Lys Ser Ser Glu Val Tyr Asn Trp Thr Val 
            100                 105                 110         


Asp Glu Val Val Gln Trp Leu Ile Thr Tyr Val Glu Leu Pro Gln Tyr 
        115                 120                 125             


Glu Glu Thr Phe Arg Lys Leu Gln Leu Ser Gly His Ala Met Pro Arg 
    130                 135                 140                 


Leu Ala Val Thr Asn Thr Thr Met Thr Gly Thr Val Leu Lys Met Thr 
145                 150                 155                 160 


Asp Arg Ser His Arg Gln Lys Leu Gln Leu Lys Ala Leu Asp Thr Val 
                165                 170                 175     


Leu Phe Gly Pro Pro Leu Leu Thr Arg His Asn His Leu Lys Asp 
            180                 185                 190     


<210>  1231
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  1231

Cys Glu Leu Val Pro Arg His Leu Arg Gly Arg Arg Ala Thr Gly Ser 
1               5                   10                  15      


Ala Ala Thr Ala Ala Ser Ser Pro Ala Ala Ala Ala Gly Asp Ser Pro 
            20                  25                  30          


Ala Leu Met Thr Asp Pro Cys Met Ser Leu Ser Pro Pro Cys Phe Thr 
        35                  40                  45              


Glu Glu Asp Arg Phe Ser Leu Glu Ala Leu Gln Thr Ile His Lys Gln 
    50                  55                  60                  


Met Asp Asp Asp Lys Asp Gly Gly Ile Glu Val Glu Glu Ser Asp Glu 
65                  70                  75                  80  


Phe Ile Arg Glu Asp Met Lys Tyr Lys Asp Ala Thr Asn Lys His Ser 
                85                  90                  95      


His Leu His Arg Glu Asp Lys His Ile Thr Ile Glu Asp Leu Trp Lys 
            100                 105                 110         


Arg Trp Lys Thr Ser Glu Val His Asn Trp Thr Leu Glu Asp Thr Leu 
        115                 120                 125             


Gln Trp Leu Ile Glu Phe Val Glu Leu Pro Gln Tyr Glu Lys Asn Phe 
    130                 135                 140                 


Arg Asp Asn Asn Val Lys Gly Thr Thr Leu Pro Arg Ile Ala Val His 
145                 150                 155                 160 


Glu Pro Ser Phe Met Ile Ser Gln Leu Lys Ile Ser Asp Arg Ser His 
                165                 170                 175     


Arg Gln Lys Leu Gln Leu Lys Ala Leu Asp Val Val Leu Phe Gly Pro 
            180                 185                 190         


Leu Thr Arg Pro Pro His Asn Trp Met Lys Asp Phe 
        195                 200                 


<210>  1232
<211>  728
<212>  PRT
<213>  Homo Sapiens

<400>  1232

Ala Pro Gly Pro Asp Gly Leu Asp Val Cys Ala Thr Cys His Glu His 
1               5                   10                  15      


Ala Thr Cys Gln Gln Arg Glu Gly Lys Lys Ile Cys Ile Cys Asn Tyr 
            20                  25                  30          


Gly Phe Val Gly Asn Gly Arg Thr Gln Cys Val Asp Lys Asn Glu Cys 
        35                  40                  45              


Gln Phe Gly Ala Thr Leu Val Cys Gly Asn His Thr Ser Cys His Asn 
    50                  55                  60                  


Thr Pro Gly Gly Phe Tyr Cys Ile Cys Leu Glu Gly Tyr Arg Ala Thr 
65                  70                  75                  80  


Asn Asn Asn Lys Thr Phe Ile Pro Asn Asp Gly Thr Phe Cys Thr Asp 
                85                  90                  95      


Ile Asp Glu Cys Glu Val Ser Gly Leu Cys Arg His Gly Gly Arg Cys 
            100                 105                 110         


Val Asn Thr His Gly Ser Phe Glu Cys Tyr Cys Met Asp Gly Tyr Leu 
        115                 120                 125             


Pro Arg Asn Gly Pro Glu Pro Phe His Pro Thr Thr Asp Ala Thr Ser 
    130                 135                 140                 


Cys Thr Glu Ile Asp Cys Gly Thr Pro Pro Glu Val Pro Asp Gly Tyr 
145                 150                 155                 160 


Ile Ile Gly Asn Tyr Thr Ser Ser Leu Gly Ser Gln Val Arg Tyr Ala 
                165                 170                 175     


Cys Arg Glu Gly Phe Phe Ser Val Pro Glu Asp Thr Val Ser Ser Cys 
            180                 185                 190         


Thr Gly Leu Gly Thr Trp Glu Ser Pro Lys Leu His Cys Gln Glu Ile 
        195                 200                 205             


Asn Cys Gly Asn Pro Pro Glu Met Arg His Ala Ile Leu Val Gly Asn 
    210                 215                 220                 


His Ser Ser Arg Leu Gly Gly Val Ala Arg Tyr Val Cys Gln Glu Gly 
225                 230                 235                 240 


Phe Glu Ser Pro Gly Gly Lys Ile Thr Ser Val Cys Thr Glu Lys Gly 
                245                 250                 255     


Thr Trp Arg Glu Ser Thr Leu Thr Cys Thr Glu Ile Leu Thr Lys Ile 
            260                 265                 270         


Asn Asp Val Ser Leu Phe Asn Asp Thr Cys Val Arg Trp Gln Ile Asn 
        275                 280                 285             


Ser Arg Arg Ile Asn Pro Lys Ile Ser Tyr Val Ile Ser Ile Lys Gly 
    290                 295                 300                 


Gln Arg Leu Asp Pro Met Glu Ser Val Arg Glu Glu Thr Val Asn Leu 
305                 310                 315                 320 


Thr Thr Asp Ser Arg Thr Pro Glu Val Cys Leu Ala Leu Tyr Pro Gly 
                325                 330                 335     


Thr Asn Tyr Thr Val Asn Ile Ser Thr Ala Pro Pro Arg Arg Ser Met 
            340                 345                 350         


Pro Ala Val Ile Gly Phe Gln Thr Ala Glu Val Asp Leu Leu Glu Asp 
        355                 360                 365             


Asp Gly Ser Phe Asn Ile Ser Ile Phe Asn Glu Thr Cys Leu Lys Leu 
    370                 375                 380                 


Asn Arg Arg Ser Arg Lys Val Gly Ser Glu His Met Tyr Gln Phe Thr 
385                 390                 395                 400 


Val Leu Gly Gln Arg Trp Tyr Leu Ala Asn Phe Ser His Ala Thr Ser 
                405                 410                 415     


Phe Asn Phe Thr Thr Arg Glu Gln Val Pro Val Val Cys Leu Asp Leu 
            420                 425                 430         


Tyr Pro Thr Thr Asp Tyr Thr Val Asn Val Thr Leu Leu Arg Ser Pro 
        435                 440                 445             


Lys Arg His Ser Val Gln Ile Thr Ile Ala Thr Pro Pro Ala Val Lys 
    450                 455                 460                 


Gln Thr Ile Ser Asn Ile Ser Gly Phe Asn Glu Thr Cys Leu Arg Trp 
465                 470                 475                 480 


Arg Ser Ile Lys Thr Ala Asp Met Glu Glu Met Tyr Leu Phe Gln Ile 
                485                 490                 495     


Trp Gly Gln Arg Trp Tyr Gln Lys Glu Phe Ala Gln Glu Met Thr Phe 
            500                 505                 510         


Asn Ile Ser Ser Ser Ser Arg Asp Pro Glu Val Cys Leu Asp Leu Arg 
        515                 520                 525             


Pro Gly Thr Asn Tyr Asn Val Ser Leu Arg Ala Leu Ser Ser Glu Leu 
    530                 535                 540                 


Pro Val Val Ile Ser Leu Thr Thr Gln Ile Thr Glu Pro Pro Leu Pro 
545                 550                 555                 560 


Glu Val Glu Phe Phe Thr Val His Arg Gly Pro Leu Pro Arg Leu Arg 
                565                 570                 575     


Leu Arg Lys Ala Lys Glu Lys Asn Gly Pro Ile Ser Ser Tyr Gln Val 
            580                 585                 590         


Leu Val Leu Pro Leu Ala Leu Gln Ser Thr Phe Ser Cys Asp Ser Glu 
        595                 600                 605             


Gly Ala Ser Ser Phe Phe Ser Asn Ala Ser Asp Ala Asp Gly Tyr Val 
    610                 615                 620                 


Ala Ala Glu Leu Leu Ala Lys Asp Val Pro Asp Asp Ala Met Glu Ile 
625                 630                 635                 640 


Pro Ile Gly Asp Arg Leu Tyr Tyr Gly Glu Tyr Tyr Asn Ala Pro Leu 
                645                 650                 655     


Lys Arg Gly Ser Asp Tyr Cys Ile Ile Leu Arg Ile Thr Ser Glu Trp 
            660                 665                 670         


Asn Lys Val Arg Arg His Ser Cys Ala Val Trp Ala Gln Val Lys Glu 
        675                 680                 685             


Ile Pro Cys Asn Cys Asn Phe Leu Arg Leu His Ile His Arg Ala Asn 
    690                 695                 700                 


Ser Gly Asp Thr Gln Ile Arg His Ser Cys Cys Cys Arg Trp Arg Val 
705                 710                 715                 720 


Leu Asp Trp Val Pro Trp Leu Leu 
                725             


<210>  1233
<211>  758
<212>  PRT
<213>  Homo Sapiens

<400>  1233

Gln Glu Ser Cys Ser Met Arg Cys Gly Ala Leu Asp Gly Pro Cys Ser 
1               5                   10                  15      


Cys His Pro Thr Cys Ser Gly Leu Gly Thr Cys Cys Leu Asp Phe Arg 
            20                  25                  30          


Asp Phe Cys Leu Glu Ile Leu Pro Tyr Ser Gly Ser Met Met Gly Gly 
        35                  40                  45              


Lys Asp Phe Val Val Arg His Phe Lys Met Ser Ser Pro Thr Asp Ala 
    50                  55                  60                  


Ser Val Ile Cys Arg Phe Lys Asp Ser Ile Gln Thr Leu Gly His Val 
65                  70                  75                  80  


Asp Ser Ser Gly Gln Val His Cys Val Ser Pro Leu Leu Tyr Glu Ser 
                85                  90                  95      


Gly Arg Ile Pro Phe Thr Val Ser Leu Asp Asn Gly His Ser Phe Pro 
            100                 105                 110         


Arg Ala Gly Thr Trp Leu Ala Val His Pro Asn Lys Val Ser Met Met 
        115                 120                 125             


Glu Lys Ser Glu Leu Val Asn Glu Thr Arg Trp Gln Tyr Tyr Gly Thr 
    130                 135                 140                 


Ala Asn Thr Ser Gly Asn Leu Ser Leu Thr Trp His Val Lys Ser Leu 
145                 150                 155                 160 


Pro Thr Gln Thr Ile Thr Ile Glu Leu Trp Gly Tyr Glu Glu Thr Gly 
                165                 170                 175     


Met Pro Tyr Ser Gln Glu Trp Thr Ala Lys Trp Ser Tyr Leu Tyr Pro 
            180                 185                 190         


Leu Ala Thr His Ile Pro Asn Ser Gly Ser Phe Thr Phe Thr Pro Lys 
        195                 200                 205             


Pro Ala Pro Pro Ser Tyr Gln Arg Trp Arg Val Gly Ala Leu Arg Ile 
    210                 215                 220                 


Ile Asp Ser Lys Asn Tyr Ala Gly Gln Lys Asp Val Gln Ala Leu Trp 
225                 230                 235                 240 


Thr Asn Asp His Ala Leu Ala Trp His Leu Ser Asp Asp Phe Arg Glu 
                245                 250                 255     


Asp Pro Val Ala Trp Ala Arg Thr Gln Cys Gln Ala Trp Glu Glu Leu 
            260                 265                 270         


Glu Asp Gln Leu Pro Asn Phe Leu Glu Glu Leu Pro Asp Cys Pro Cys 
        275                 280                 285             


Thr Leu Thr Gln Ala Arg Ala Asp Ser Gly Arg Phe Phe Thr Asp Tyr 
    290                 295                 300                 


Gly Cys Asp Met Glu Gln Gly Ser Val Cys Thr Tyr His Pro Gly Ala 
305                 310                 315                 320 


Val His Cys Val Arg Ser Val Gln Ala Ser Leu Arg Tyr Gly Ser Gly 
                325                 330                 335     


Gln Gln Cys Cys Tyr Thr Ala Asp Gly Thr Gln Leu Leu Thr Ala Asp 
            340                 345                 350         


Ser Ser Gly Gly Ser Thr Pro Asp Arg Gly His Asp Trp Gly Ala Pro 
        355                 360                 365             


Pro Phe Arg Thr Pro Pro Arg Val Pro Ser Met Ser His Trp Leu Tyr 
    370                 375                 380                 


Asp Val Leu Ser Phe Tyr Tyr Cys Cys Leu Trp Ala Pro Asp Cys Pro 
385                 390                 395                 400 


Arg Tyr Met Gln Arg Arg Pro Ser Asn Asp Cys Arg Asn Tyr Arg Pro 
                405                 410                 415     


Pro Arg Leu Ala Ser Ala Phe Gly Asp Pro His Phe Val Thr Phe Asp 
            420                 425                 430         


Gly Thr Asn Phe Thr Phe Asn Gly Arg Gly Glu Tyr Val Leu Leu Glu 
        435                 440                 445             


Ala Ala Leu Thr Asp Leu Arg Val Gln Ala Arg Ala Gln Pro Gly Thr 
    450                 455                 460                 


Met Ser Asn Gly Thr Glu Thr Arg Gly Thr Gly Leu Thr Ala Val Ala 
465                 470                 475                 480 


Val Gln Glu Gly Asn Ser Asp Val Val Glu Val Arg Leu Ala Asn Arg 
                485                 490                 495     


Thr Gly Gly Leu Glu Val Leu Leu Asn Gln Glu Val Leu Ser Phe Thr 
            500                 505                 510         


Glu Gln Ser Trp Met Asp Leu Lys Gly Met Phe Leu Ser Val Ala Ala 
        515                 520                 525             


Gly Asp Arg Val Ser Ile Met Leu Ala Ser Gly Ala Gly Leu Glu Val 
    530                 535                 540                 


Ser Val Gln Gly Pro Phe Leu Ser Val Ser Val Leu Leu Pro Glu Lys 
545                 550                 555                 560 


Phe Leu Thr His Thr His Gly Leu Leu Gly Thr Leu Asn Asn Asp Pro 
                565                 570                 575     


Thr Asp Asp Phe Thr Leu His Ser Gly Arg Val Leu Pro Pro Gly Thr 
            580                 585                 590         


Ser Pro Gln Glu Leu Phe Leu Phe Gly Ala Asn Trp Thr Val His Asn 
        595                 600                 605             


Ala Ser Ser Leu Leu Thr Tyr Asp Ser Trp Phe Leu Val His Asn Phe 
    610                 615                 620                 


Leu Tyr Gln Pro Lys His Asp Pro Thr Phe Glu Pro Leu Phe Pro Ser 
625                 630                 635                 640 


Glu Thr Thr Leu Asn Pro Ser Leu Ala Gln Glu Ala Ala Lys Leu Cys 
                645                 650                 655     


Gly Asp Asp His Phe Cys Asn Phe Asp Val Ala Ala Thr Gly Ser Leu 
            660                 665                 670         


Ser Thr Gly Thr Ala Thr Arg Val Ala His Gln Leu His Gln Arg Arg 
        675                 680                 685             


Met Gln Ser Leu Gln Pro Val Val Ser Cys Gly Trp Leu Ala Pro Pro 
    690                 695                 700                 


Pro Asn Gly Gln Lys Glu Gly Asn Arg Tyr Leu Ala Gly Ser Thr Ile 
705                 710                 715                 720 


Tyr Phe His Cys Asp Asn Gly Tyr Ser Leu Ala Gly Ala Glu Thr Ser 
                725                 730                 735     


Thr Cys Gln Ala Asp Gly Thr Trp Ser Ser Pro Thr Pro Lys Cys Gln 
            740                 745                 750         


Pro Gly Arg Ser Tyr Ala 
        755             


<210>  1234
<211>  249
<212>  PRT
<213>  Homo Sapiens

<400>  1234

Phe Gly Pro Ala Gln Leu Thr Gly Gly Phe Asp Asp Leu Gln Val Cys 
1               5                   10                  15      


Ala Asp Pro Gly Ile Pro Glu Asn Gly Phe Arg Thr Pro Ser Gly Gly 
            20                  25                  30          


Val Phe Phe Glu Gly Ser Val Ala Arg Phe His Cys Gln Asp Gly Phe 
        35                  40                  45              


Lys Leu Lys Gly Ala Thr Lys Arg Leu Cys Leu Lys His Phe Asn Gly 
    50                  55                  60                  


Thr Leu Gly Trp Ile Pro Ser Asp Asn Ser Ile Cys Val Gln Glu Asp 
65                  70                  75                  80  


Cys Arg Ile Pro Gln Ile Glu Asp Ala Glu Ile His Asn Lys Thr Tyr 
                85                  90                  95      


Arg His Gly Glu Lys Leu Ile Ile Thr Cys His Glu Gly Phe Lys Ile 
            100                 105                 110         


Arg Tyr Pro Asp Leu His Asn Met Val Ser Leu Cys Arg Asp Asp Gly 
        115                 120                 125             


Thr Trp Asn Asn Leu Pro Ile Cys Gln Gly Cys Leu Arg Pro Leu Ala 
    130                 135                 140                 


Ser Ser Asn Gly Tyr Val Asn Ile Ser Glu Leu Gln Thr Ser Phe Pro 
145                 150                 155                 160 


Val Gly Thr Val Ile Ser Tyr Arg Cys Phe Pro Gly Phe Lys Leu Asp 
                165                 170                 175     


Gly Ser Ala Tyr Leu Glu Cys Leu Gln Asn Leu Ile Trp Ser Ser Ser 
            180                 185                 190         


Pro Pro Arg Cys Leu Ala Leu Glu Gly Gly Arg Pro Glu His Leu Phe 
        195                 200                 205             


Pro Val Leu Tyr Phe Pro His Ile Arg Leu Ala Ala Ala Val Leu Tyr 
    210                 215                 220                 


Phe Cys Pro Val Leu Lys Ser Ser Pro Thr Pro Ala Pro Thr Cys Ser 
225                 230                 235                 240 


Ser Thr Ser Thr Thr Thr Ser Leu Phe 
                245                 


<210>  1235
<211>  41
<212>  PRT
<213>  Homo Sapiens

<400>  1235

Asp Gly Gly Glu Glu Gln Thr Leu Ser Thr Glu Ala Glu Thr Trp Glu 
1               5                   10                  15      


Gly Ala Gly Pro Ser Ile Gln Leu Gln Leu Gln Glu Val Lys Thr Gly 
            20                  25                  30          


Lys Ala Ser Gln Phe Phe Gly Leu Met 
        35                  40      


<210>  1236
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  1236

Gln Gly Asp Thr Arg Gly Asp Gly Ser Leu Pro Lys Pro Ser Leu Ser 
1               5                   10                  15      


Ala Trp Pro Ser Ser Val Val Pro Ala Asn Ser Asn Val Thr Leu Arg 
            20                  25                  30          


Cys Trp Thr Pro Ala Arg Gly Val Ser Phe Val Leu Arg Lys Gly Gly 
        35                  40                  45              


Ile Ile Leu Glu Ser Pro Lys Pro Leu Asp Ser Thr Glu Gly Ala Ala 
    50                  55                  60                  


Glu Phe His Leu Asn Asn Leu Lys Val Arg Asn Ala Gly Glu Tyr Thr 
65                  70                  75                  80  


Cys Glu Tyr Tyr Arg Lys Ala Ser Pro His Ile Leu Ser Gln Arg Ser 
                85                  90                  95      


Asp Val Leu Leu Leu Leu Val Thr Gly His Leu Ser Lys Pro Phe Leu 
            100                 105                 110         


Arg Thr Tyr Gln Arg Gly Thr Val Thr Ala Gly Gly Arg Val Thr Leu 
        115                 120                 125             


Gln Cys Gln Lys Arg Asp Gln Leu Phe Val Pro Ile Met Phe Ala Leu 
    130                 135                 140                 


Leu Lys Ala Gly Thr Pro Ser Pro Ile Gln Leu Gln Ser Pro Ala Gly 
145                 150                 155                 160 


Lys Glu Ile Asp Phe Ser Leu Val Asp Val Thr Ala Gly Asp Ala Gly 
                165                 170                 175     


Asn Tyr Ser Cys Met Tyr Tyr Gln Thr Lys Ser Pro Phe Trp Ala Ser 
            180                 185                 190         


Glu Pro Ser Asp Gln Leu Glu Ile Leu Val Thr Val Pro Pro Gly Thr 
        195                 200                 205             


Thr Ser Ser Asn Tyr Ser Leu Gly Asn Phe Val Arg 
    210                 215                 220 


<210>  1237
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  1237

Leu Gly His Gln Glu Phe Ala Arg Pro Ser Arg Gly Tyr Leu Ala Phe 
1               5                   10                  15      


Arg Asp Asp Ser Ile Trp Pro Gln Glu Glu Pro Ala Ile Arg Pro Arg 
            20                  25                  30          


Ser Ser Gln Arg Val Pro Pro Met Gly Ile Gln His Ser Lys Glu Leu 
        35                  40                  45              


Asn Arg Thr Cys Cys Leu Asn Gly Gly Thr Cys Met Leu Gly Ser Phe 
    50                  55                  60                  


Cys Ala Cys Pro Pro Ser Phe Tyr Gly Arg Asn Cys Glu His Asp Val 
65                  70                  75                  80  


Arg Lys Glu Asn Cys Gly Ser Val Pro His Asp Thr Trp Leu Pro Lys 
                85                  90                  95      


Lys Cys Ser Leu Cys Lys Cys Trp His Gly Gln Leu Arg Cys Phe Pro 
            100                 105                 110         


Gln Ala Phe Leu Pro Gly Cys Asp 
        115                 120 


<210>  1238
<211>  725
<212>  PRT
<213>  Homo Sapiens

<400>  1238

Met Asp Leu Ile Leu Ile Asn Ser Leu Pro Leu Val Ser Asp Ala Glu 
1               5                   10                  15      


Thr Ser Leu Thr Cys Ile Ala Ser Gly Trp Arg Pro His Glu Pro Ile 
            20                  25                  30          


Thr Ile Gly Arg Asp Phe Glu Ala Leu Met Asn Gln His Gln Asp Pro 
        35                  40                  45              


Leu Glu Val Thr Gln Asp Val Thr Arg Glu Trp Ala Lys Lys Val Val 
    50                  55                  60                  


Trp Lys Arg Glu Lys Ala Ser Lys Ile Asn Gly Ala Tyr Phe Cys Glu 
65                  70                  75                  80  


Gly Arg Val Arg Gly Glu Ala Ile Arg Ile Arg Thr Met Lys Met Arg 
                85                  90                  95      


Gln Gln Ala Ser Phe Leu Pro Ala Thr Leu Thr Met Thr Val Asp Lys 
            100                 105                 110         


Gly Asp Asn Val Asn Ile Ser Phe Lys Lys Val Leu Ile Lys Glu Glu 
        115                 120                 125             


Asp Ala Val Ile Tyr Lys Asn Gly Ser Phe Ile His Ser Val Pro Arg 
    130                 135                 140                 


His Glu Val Pro Asp Ile Leu Glu Val His Leu Pro His Ala Gln Pro 
145                 150                 155                 160 


Gln Asp Ala Gly Val Tyr Ser Ala Arg Tyr Ile Gly Gly Asn Leu Phe 
                165                 170                 175     


Thr Ser Ala Phe Thr Arg Leu Ile Val Arg Arg Cys Glu Ala Gln Lys 
            180                 185                 190         


Trp Gly Pro Glu Cys Asn His Leu Cys Thr Ala Cys Met Asn Asn Gly 
        195                 200                 205             


Val Cys His Glu Asp Thr Gly Glu Cys Ile Cys Pro Pro Gly Phe Met 
    210                 215                 220                 


Gly Arg Thr Cys Glu Lys Ala Cys Glu Leu His Thr Phe Gly Arg Thr 
225                 230                 235                 240 


Cys Lys Glu Arg Cys Ser Gly Gln Glu Gly Cys Lys Ser Tyr Val Phe 
                245                 250                 255     


Cys Leu Pro Asp Pro Tyr Gly Cys Ser Cys Ala Thr Gly Trp Lys Gly 
            260                 265                 270         


Leu Gln Cys Asn Glu Ala Cys His Pro Gly Phe Tyr Gly Pro Asp Cys 
        275                 280                 285             


Lys Leu Arg Cys Ser Cys Asn Asn Gly Glu Met Cys Asp Arg Phe Gln 
    290                 295                 300                 


Gly Cys Leu Cys Ser Pro Gly Trp Gln Gly Leu Gln Cys Glu Arg Glu 
305                 310                 315                 320 


Gly Ile Pro Arg Met Thr Pro Lys Ile Val Asp Leu Pro Asp His Ile 
                325                 330                 335     


Glu Val Asn Ser Gly Lys Phe Asn Pro Ile Cys Lys Ala Ser Gly Trp 
            340                 345                 350         


Pro Leu Pro Thr Asn Glu Glu Met Thr Leu Val Lys Pro Asp Gly Thr 
        355                 360                 365             


Val Leu His Pro Lys Asp Phe Asn His Thr Asp His Phe Ser Val Ala 
    370                 375                 380                 


Ile Phe Thr Ile His Arg Ile Leu Pro Pro Asp Ser Gly Val Trp Val 
385                 390                 395                 400 


Cys Ser Val Asn Thr Val Ala Gly Met Val Glu Lys Pro Phe Asn Ile 
                405                 410                 415     


Ser Val Lys Val Leu Pro Lys Pro Leu Asn Ala Pro Asn Val Ile Asp 
            420                 425                 430         


Thr Gly His Asn Phe Ala Val Ile Asn Ile Ser Ser Glu Pro Tyr Phe 
        435                 440                 445             


Gly Asp Gly Pro Ile Lys Ser Lys Lys Leu Leu Tyr Lys Pro Val Asn 
    450                 455                 460                 


His Tyr Glu Ala Trp Gln His Ile Gln Val Thr Asn Glu Ile Val Thr 
465                 470                 475                 480 


Leu Asn Tyr Leu Glu Pro Arg Thr Glu Tyr Glu Leu Cys Val Gln Leu 
                485                 490                 495     


Val Arg Arg Gly Glu Gly Gly Glu Gly His Pro Gly Pro Val Arg Arg 
            500                 505                 510         


Phe Thr Thr Ala Ser Ile Gly Leu Pro Pro Pro Arg Gly Leu Asn Leu 
        515                 520                 525             


Leu Pro Lys Ser Gln Thr Thr Leu Asn Leu Thr Trp Gln Pro Ile Phe 
    530                 535                 540                 


Pro Ser Ser Glu Asp Asp Phe Tyr Val Glu Val Glu Arg Arg Ser Val 
545                 550                 555                 560 


Gln Lys Ser Asp Gln Gln Asn Ile Lys Val Pro Gly Asn Leu Thr Ser 
                565                 570                 575     


Val Leu Leu Asn Asn Leu His Pro Arg Glu Gln Tyr Val Val Arg Ala 
            580                 585                 590         


Arg Val Asn Thr Lys Ala Gln Gly Glu Trp Ser Glu Asp Leu Thr Ala 
        595                 600                 605             


Trp Thr Leu Ser Asp Ile Leu Pro Pro Gln Pro Glu Asn Ile Lys Ile 
    610                 615                 620                 


Ser Asn Ile Thr His Ser Ser Ala Val Ile Ser Trp Thr Ile Leu Asp 
625                 630                 635                 640 


Gly Tyr Ser Ile Ser Ser Ile Thr Ile Arg Tyr Lys Val Gln Gly Lys 
                645                 650                 655     


Asn Glu Asp Gln His Val Asp Val Lys Ile Lys Asn Ala Thr Ile Thr 
            660                 665                 670         


Gln Tyr Gln Leu Lys Gly Leu Glu Pro Glu Thr Ala Tyr Gln Val Asp 
        675                 680                 685             


Ile Phe Ala Glu Asn Asn Ile Gly Ser Ser Asn Pro Ala Phe Ser His 
    690                 695                 700                 


Glu Leu Val Thr Leu Pro Glu Ser Gln Ala Pro Ala Asp Leu Gly Gly 
705                 710                 715                 720 


Gly Lys Met Leu Leu 
                725 


<210>  1239
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  1239

Ile Leu Glu Asn Gly Val Asn Val Thr Val Ser Gln Met Thr Ser Val 
1               5                   10                  15      


Leu Asn Gly Arg Thr Arg Arg Phe Ala Asp Ile Gln Leu Gln His Gly 
            20                  25                  30          


Ala Leu Cys Phe Asn Ile Arg Tyr Gly Thr Thr Val Glu Glu Glu Lys 
        35                  40                  45              


Asn His Val Leu Glu Ile Ala Arg Gln Arg Ala Val Ala Gln Ala Trp 
    50                  55                  60                  


Thr Lys Glu Gln Arg Arg Leu Gln Glu Gly Glu Glu Gly Ile Arg Ala 
65                  70                  75                  80  


Trp Thr Glu Gly Glu Lys Gln Gln Leu Leu Ser Thr Gly Arg Val Gln 
                85                  90                  95      


Gly Tyr Asp Gly Tyr Phe Val Leu Ser Val Glu Gln Tyr Leu Glu Leu 
            100                 105                 110         


Ser Asp Ser Ala Asn Asn Ile His Phe Met Arg Gln Ser Glu Ile Gly 
        115                 120                 125             


Arg Arg 
    130 


<210>  1240
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  1240

Leu Tyr Cys Gln Lys Gly Leu Ser Met Thr Val Glu Ala Asp Pro Ala 
1               5                   10                  15      


Asn Met Phe Asn Trp Thr Thr Glu Glu Val Glu Thr Cys Asp Lys Gly 
            20                  25                  30          


Ala Leu Cys Gln Glu Thr Ile Leu Ile Ile Lys Ala Gly Thr Glu Thr 
        35                  40                  45              


Ala Ile Leu Ala Thr Lys Gly Cys Ile Pro Glu Gly Glu Glu Ala Ile 
    50                  55                  60                  


Thr Ile Val Gln His Ser Ser Pro Pro Gly Leu Ile Val Thr Ser Tyr 
65                  70                  75                  80  


Ser Asn Tyr Cys Glu Asp Ser Phe Cys Asn Asp Lys Asp Ser Leu Ser 
                85                  90                  95      


Gln Phe Trp Glu Phe Ser Glu Thr Thr Ala Ser Thr Val Ser Thr Thr 
            100                 105                 110         


Leu His Cys Pro Thr Cys Val Ala Leu Gly Thr Cys Phe Ser Ala Pro 
        115                 120                 125             


Ser Leu Pro Cys Pro Asn Gly Thr Thr Arg Cys Tyr Gln Gly Lys Leu 
    130                 135                 140                 


Glu Ile Thr Gly Gly Gly Ile Glu Ser Ser Val Glu Val Lys Gly Cys 
145                 150                 155                 160 


Thr Ala Met Ile Gly Cys Arg Leu Met Ser Gly Ile Leu Ala Val Gly 
                165                 170                 175     


Pro Met Phe Val Arg Glu Ala Cys Pro His Gln Leu Leu Thr Gln Pro 
            180                 185                 190         


Arg Lys Thr Glu Asn 
        195         


<210>  1241
<211>  679
<212>  PRT
<213>  Homo Sapiens

<400>  1241

Val Pro Asp Lys Thr Val Arg Trp Cys Ala Val Ser Glu His Glu Ala 
1               5                   10                  15      


Thr Lys Cys Gln Ser Phe Arg Asp His Met Lys Ser Val Ile Pro Ser 
            20                  25                  30          


Asp Gly Pro Ser Val Ala Cys Val Lys Lys Ala Ser Tyr Leu Asp Cys 
        35                  40                  45              


Ile Arg Ala Ile Ala Ala Asn Glu Ala Asp Ala Val Thr Leu Asp Ala 
    50                  55                  60                  


Gly Leu Val Tyr Asp Ala Tyr Leu Ala Pro Asn Asn Leu Lys Pro Val 
65                  70                  75                  80  


Val Ala Glu Phe Tyr Gly Ser Lys Glu Asp Pro Gln Thr Phe Tyr Tyr 
                85                  90                  95      


Ala Val Ala Val Val Lys Lys Asp Ser Gly Phe Gln Met Asn Gln Leu 
            100                 105                 110         


Arg Gly Lys Lys Ser Cys His Thr Gly Leu Gly Arg Ser Ala Gly Trp 
        115                 120                 125             


Asn Ile Pro Ile Gly Leu Leu Tyr Cys Asp Leu Pro Glu Pro Arg Lys 
    130                 135                 140                 


Pro Leu Glu Lys Ala Val Ala Asn Phe Phe Ser Gly Ser Cys Ala Pro 
145                 150                 155                 160 


Cys Ala Asp Gly Thr Asp Phe Pro Gln Leu Cys Gln Leu Cys Pro Gly 
                165                 170                 175     


Cys Gly Cys Ser Thr Leu Asn Gln Tyr Phe Gly Tyr Ser Gly Ala Phe 
            180                 185                 190         


Lys Cys Leu Lys Asn Gly Ala Gly Asp Val Ala Phe Val Lys His Ser 
        195                 200                 205             


Thr Ile Phe Glu Asn Leu Ala Asn Lys Ala Asp Arg Asp Gln Tyr Glu 
    210                 215                 220                 


Leu Leu Cys Leu Asp Asn Thr Arg Lys Pro Val Asp Glu Tyr Lys Asp 
225                 230                 235                 240 


Cys His Leu Ala Gln Val Pro Ser His Thr Val Val Ala Arg Ser Met 
                245                 250                 255     


Gly Gly Lys Glu Asp Leu Ile Trp Glu Leu Leu Asn Gln Ala Gln Glu 
            260                 265                 270         


His Phe Gly Lys Asp Lys Ser Lys Glu Phe Gln Leu Phe Ser Ser Pro 
        275                 280                 285             


His Gly Lys Asp Leu Leu Phe Lys Asp Ser Ala His Gly Phe Leu Lys 
    290                 295                 300                 


Val Pro Pro Arg Met Asp Ala Lys Met Tyr Leu Gly Tyr Glu Tyr Val 
305                 310                 315                 320 


Thr Ala Ile Arg Asn Leu Arg Glu Gly Thr Cys Gln Glu Ala Pro Thr 
                325                 330                 335     


Asp Glu Cys Lys Pro Val Lys Trp Cys Ala Leu Ser His His Glu Arg 
            340                 345                 350         


Leu Lys Cys Asp Glu Trp Ser Val Asn Ser Val Gly Lys Ile Glu Cys 
        355                 360                 365             


Val Ser Ala Glu Thr Thr Glu Asp Cys Ile Ala Lys Ile Met Asn Gly 
    370                 375                 380                 


Glu Ala Asp Ala Met Ser Leu Asp Gly Gly Phe Val Tyr Ile Ala Gly 
385                 390                 395                 400 


Lys Cys Gly Leu Val Pro Val Leu Ala Glu Asn Tyr Asn Lys Ser Asp 
                405                 410                 415     


Asn Cys Glu Asp Thr Pro Glu Ala Gly Tyr Phe Ala Val Ala Val Val 
            420                 425                 430         


Lys Lys Ser Ala Ser Asp Leu Thr Trp Asp Asn Leu Lys Gly Lys Lys 
        435                 440                 445             


Ser Cys His Thr Ala Val Gly Arg Thr Ala Gly Trp Asn Ile Pro Met 
    450                 455                 460                 


Gly Leu Leu Tyr Asn Lys Ile Asn His Cys Arg Phe Asp Glu Phe Phe 
465                 470                 475                 480 


Ser Glu Gly Cys Ala Pro Gly Ser Lys Lys Asp Ser Ser Leu Cys Lys 
                485                 490                 495     


Leu Cys Met Gly Ser Gly Leu Asn Leu Cys Glu Pro Asn Asn Lys Glu 
            500                 505                 510         


Gly Tyr Tyr Gly Tyr Thr Gly Ala Phe Arg Cys Leu Val Glu Lys Gly 
        515                 520                 525             


Asp Val Ala Phe Val Lys His Gln Thr Val Pro Gln Asn Thr Gly Gly 
    530                 535                 540                 


Lys Asn Pro Asp Pro Trp Ala Lys Asn Leu Asn Glu Lys Asp Tyr Glu 
545                 550                 555                 560 


Leu Leu Cys Leu Asp Gly Thr Arg Lys Pro Val Glu Glu Tyr Ala Asn 
                565                 570                 575     


Cys His Leu Ala Arg Ala Pro Asn His Ala Val Val Thr Arg Lys Asp 
            580                 585                 590         


Lys Glu Ala Cys Val His Lys Ile Leu Arg Gln Gln Gln His Leu Phe 
        595                 600                 605             


Gly Ser Asn Val Thr Asp Cys Ser Gly Asn Phe Cys Leu Phe Arg Ser 
    610                 615                 620                 


Glu Thr Lys Asp Leu Leu Phe Arg Asp Asp Thr Val Cys Leu Ala Lys 
625                 630                 635                 640 


Leu His Asp Arg Asn Thr Tyr Glu Lys Tyr Leu Gly Glu Glu Tyr Val 
                645                 650                 655     


Lys Ala Val Gly Asn Leu Arg Lys Cys Ser Thr Ser Ser Leu Leu Glu 
            660                 665                 670         


Ala Cys Thr Phe Arg Arg Pro 
        675                 


<210>  1242
<211>  697
<212>  PRT
<213>  Homo Sapiens

<400>  1242

Arg Gly Ser Cys Gln Ala Cys Gly Asp Ser Val Leu Val Val Ser Glu 
1               5                   10                  15      


Asp Val Asn Tyr Glu Pro Asp Leu Asp Phe His Gln Gly Arg Leu Tyr 
            20                  25                  30          


Trp Ser Asp Leu Gln Ala Met Phe Leu Gln Phe Leu Gly Glu Gly Arg 
        35                  40                  45              


Leu Glu Asp Thr Ile Arg Gln Thr Ser Leu Arg Glu Arg Val Ala Gly 
    50                  55                  60                  


Ser Ala Gly Met Ala Ala Leu Thr Gln Asp Ile Arg Ala Ala Leu Ser 
65                  70                  75                  80  


Arg Gln Lys Leu Asp His Val Trp Thr Asp Thr His Tyr Val Gly Leu 
                85                  90                  95      


Gln Phe Pro Asp Pro Ala His Pro Asn Thr Leu His Trp Val Asp Glu 
            100                 105                 110         


Ala Gly Lys Val Gly Glu Gln Leu Pro Leu Glu Asp Pro Asp Val Tyr 
        115                 120                 125             


Cys Pro Tyr Ser Ala Ile Gly Asn Val Thr Gly Glu Leu Val Tyr Ala 
    130                 135                 140                 


His Tyr Gly Arg Pro Glu Asp Leu Gln Asp Leu Arg Ala Arg Gly Val 
145                 150                 155                 160 


Asp Pro Val Gly Arg Leu Leu Leu Val Arg Val Gly Val Ile Ser Phe 
                165                 170                 175     


Ala Gln Lys Val Thr Asn Ala Gln Asp Phe Gly Ala Gln Gly Val Leu 
            180                 185                 190         


Ile Tyr Pro Glu Pro Ala Asp Phe Ser Gln Asp Pro Pro Lys Pro Ser 
        195                 200                 205             


Leu Ser Ser Gln Gln Ala Val Tyr Gly His Val His Leu Gly Thr Gly 
    210                 215                 220                 


Asp Pro Tyr Thr Pro Gly Phe Pro Ser Phe Asn Gln Thr Gln Phe Pro 
225                 230                 235                 240 


Pro Val Ala Ser Ser Gly Leu Pro Ser Ile Pro Ala Gln Pro Ile Ser 
                245                 250                 255     


Ala Asp Ile Ala Ser Arg Leu Leu Arg Lys Leu Lys Gly Pro Val Ala 
            260                 265                 270         


Pro Gln Glu Trp Gln Gly Ser Leu Leu Gly Ser Pro Tyr His Leu Gly 
        275                 280                 285             


Pro Gly Pro Arg Leu Arg Leu Val Val Asn Asn His Arg Thr Ser Thr 
    290                 295                 300                 


Pro Ile Asn Asn Ile Phe Gly Cys Ile Glu Gly Arg Ser Glu Pro Asp 
305                 310                 315                 320 


His Tyr Val Val Ile Gly Ala Gln Arg Asp Ala Trp Gly Pro Gly Ala 
                325                 330                 335     


Ala Lys Ser Ala Val Gly Thr Ala Ile Leu Leu Glu Leu Val Arg Thr 
            340                 345                 350         


Phe Ser Ser Met Val Ser Asn Gly Phe Arg Pro Arg Arg Ser Leu Leu 
        355                 360                 365             


Phe Ile Ser Trp Asp Gly Gly Asp Phe Gly Ser Val Gly Ser Thr Glu 
    370                 375                 380                 


Trp Leu Glu Gly Tyr Leu Ser Val Leu His Leu Lys Ala Val Val Tyr 
385                 390                 395                 400 


Val Ser Leu Asp Asn Ala Val Leu Gly Asp Asp Lys Phe His Ala Lys 
                405                 410                 415     


Thr Ser Pro Leu Leu Thr Ser Leu Ile Glu Ser Val Leu Lys Gln Val 
            420                 425                 430         


Asp Ser Pro Asn His Ser Gly Gln Thr Leu Tyr Glu Gln Val Val Phe 
        435                 440                 445             


Thr Asn Pro Ser Trp Asp Ala Glu Val Ile Arg Pro Leu Pro Met Asp 
    450                 455                 460                 


Ser Ser Ala Tyr Ser Phe Thr Ala Phe Val Gly Val Pro Ala Val Glu 
465                 470                 475                 480 


Phe Ser Phe Met Glu Asp Asp Gln Ala Tyr Pro Phe Leu His Thr Lys 
                485                 490                 495     


Glu Asp Thr Tyr Glu Asn Leu His Lys Val Leu Gln Gly Arg Leu Pro 
            500                 505                 510         


Ala Val Ala Gln Ala Val Ala Gln Leu Ala Gly Gln Leu Leu Ile Arg 
        515                 520                 525             


Leu Ser His Asp Arg Leu Leu Pro Leu Asp Phe Gly Arg Tyr Gly Asp 
    530                 535                 540                 


Val Val Leu Arg His Ile Gly Asn Leu Asn Glu Phe Ser Gly Asp Leu 
545                 550                 555                 560 


Lys Ala Arg Gly Leu Thr Leu Gln Trp Val Tyr Ser Ala Arg Gly Asp 
                565                 570                 575     


Tyr Ile Arg Ala Ala Glu Lys Leu Arg Gln Glu Ile Tyr Ser Ser Glu 
            580                 585                 590         


Glu Arg Asp Glu Arg Leu Thr Arg Met Tyr Asn Val Arg Ile Met Arg 
        595                 600                 605             


Val Glu Phe Tyr Phe Leu Ser Gln Tyr Val Ser Pro Ala Asp Ser Pro 
    610                 615                 620                 


Phe Arg His Ile Phe Met Gly Arg Gly Asp His Thr Leu Gly Ala Leu 
625                 630                 635                 640 


Leu Asp His Leu Arg Leu Leu Arg Ser Asn Ser Ser Gly Thr Pro Gly 
                645                 650                 655     


Ala Thr Ser Ser Thr Gly Phe Gln Glu Ser Arg Phe Arg Arg Gln Leu 
            660                 665                 670         


Ala Leu Leu Thr Trp Thr Leu Gln Gly Ala Ala Asn Ala Leu Ser Gly 
        675                 680                 685             


Asp Val Trp Asn Ile Asp Asn Asn Phe 
    690                 695         


<210>  1243
<211>  672
<212>  PRT
<213>  Homo Sapiens

<400>  1243

Cys Lys Gly Val Glu Pro Lys Thr Glu Cys Glu Arg Leu Ala Gly Thr 
1               5                   10                  15      


Glu Ser Pro Val Arg Glu Glu Pro Gly Glu Asp Phe Pro Ala Ala Arg 
            20                  25                  30          


Arg Leu Tyr Trp Asp Asp Leu Lys Arg Lys Leu Ser Glu Lys Leu Asp 
        35                  40                  45              


Ser Thr Asp Phe Thr Gly Thr Ile Lys Leu Leu Asn Glu Asn Ser Tyr 
    50                  55                  60                  


Val Pro Arg Glu Ala Gly Ser Gln Lys Asp Glu Asn Leu Ala Leu Tyr 
65                  70                  75                  80  


Val Glu Asn Gln Phe Arg Glu Phe Lys Leu Ser Lys Val Trp Arg Asp 
                85                  90                  95      


Gln His Phe Val Lys Ile Gln Val Lys Asp Ser Ala Gln Asn Ser Val 
            100                 105                 110         


Ile Ile Val Asp Lys Asn Gly Arg Leu Val Tyr Leu Val Glu Asn Pro 
        115                 120                 125             


Gly Gly Tyr Val Ala Tyr Ser Lys Ala Ala Thr Val Thr Gly Lys Leu 
    130                 135                 140                 


Val His Ala Asn Phe Gly Thr Lys Lys Asp Phe Glu Asp Leu Tyr Thr 
145                 150                 155                 160 


Pro Val Asn Gly Ser Ile Val Ile Val Arg Ala Gly Lys Ile Thr Phe 
                165                 170                 175     


Ala Glu Lys Val Ala Asn Ala Glu Ser Leu Asn Ala Ile Gly Val Leu 
            180                 185                 190         


Ile Tyr Met Asp Gln Thr Lys Phe Pro Ile Val Asn Ala Glu Leu Ser 
        195                 200                 205             


Phe Phe Gly His Ala His Leu Gly Thr Gly Asp Pro Tyr Thr Pro Gly 
    210                 215                 220                 


Phe Pro Ser Phe Asn His Thr Gln Phe Pro Pro Ser Arg Ser Ser Gly 
225                 230                 235                 240 


Leu Pro Asn Ile Pro Val Gln Thr Ile Ser Arg Ala Ala Ala Glu Lys 
                245                 250                 255     


Leu Phe Gly Asn Met Glu Gly Asp Cys Pro Ser Asp Trp Lys Thr Asp 
            260                 265                 270         


Ser Thr Cys Arg Met Val Thr Ser Glu Ser Lys Asn Val Lys Leu Thr 
        275                 280                 285             


Val Ser Asn Val Leu Lys Glu Ile Lys Ile Leu Asn Ile Phe Gly Val 
    290                 295                 300                 


Ile Lys Gly Phe Val Glu Pro Asp His Tyr Val Val Val Gly Ala Gln 
305                 310                 315                 320 


Arg Asp Ala Trp Gly Pro Gly Ala Ala Lys Ser Gly Val Gly Thr Ala 
                325                 330                 335     


Leu Leu Leu Lys Leu Ala Gln Met Phe Ser Asp Met Val Leu Lys Asp 
            340                 345                 350         


Gly Phe Gln Pro Ser Arg Ser Ile Ile Phe Ala Ser Trp Ser Ala Gly 
        355                 360                 365             


Asp Phe Gly Ser Val Gly Ala Thr Glu Trp Leu Glu Gly Tyr Leu Ser 
    370                 375                 380                 


Ser Leu His Leu Lys Ala Phe Thr Tyr Ile Asn Leu Asp Lys Ala Val 
385                 390                 395                 400 


Leu Gly Thr Ser Asn Phe Lys Val Ser Ala Ser Pro Leu Leu Tyr Thr 
                405                 410                 415     


Leu Ile Glu Lys Thr Met Gln Asn Val Lys His Pro Val Thr Gly Gln 
            420                 425                 430         


Phe Leu Tyr Gln Asp Ser Asn Trp Ala Ser Lys Val Glu Lys Leu Thr 
        435                 440                 445             


Leu Asp Asn Ala Ala Phe Pro Phe Leu Ala Tyr Ser Gly Ile Pro Ala 
    450                 455                 460                 


Val Ser Phe Cys Phe Cys Glu Asp Thr Asp Tyr Pro Tyr Leu Gly Thr 
465                 470                 475                 480 


Thr Met Asp Thr Tyr Lys Glu Leu Ile Glu Arg Ile Pro Glu Leu Asn 
                485                 490                 495     


Lys Val Ala Arg Ala Ala Ala Glu Val Ala Gly Gln Phe Val Ile Lys 
            500                 505                 510         


Leu Thr His Asp Val Glu Leu Asn Leu Asp Tyr Glu Arg Tyr Asn Ser 
        515                 520                 525             


Gln Leu Leu Ser Phe Val Arg Asp Leu Asn Gln Tyr Arg Ala Asp Ile 
    530                 535                 540                 


Lys Glu Met Gly Leu Ser Leu Gln Trp Leu Tyr Ser Ala Arg Gly Asp 
545                 550                 555                 560 


Phe Phe Arg Ala Thr Ser Arg Leu Thr Thr Asp Phe Gly Asn Ala Glu 
                565                 570                 575     


Lys Thr Asp Arg Phe Val Met Lys Lys Leu Asn Asp Arg Val Met Arg 
            580                 585                 590         


Val Glu Tyr His Phe Leu Ser Pro Tyr Val Ser Pro Lys Glu Ser Pro 
        595                 600                 605             


Phe Arg His Val Phe Trp Gly Ser Gly Ser His Thr Leu Pro Ala Leu 
    610                 615                 620                 


Leu Glu Asn Leu Lys Leu Arg Lys Gln Asn Asn Gly Ala Phe Asn Glu 
625                 630                 635                 640 


Thr Leu Phe Arg Asn Gln Leu Ala Leu Ala Thr Trp Thr Ile Gln Gly 
                645                 650                 655     


Ala Ala Asn Ala Leu Ser Gly Asp Val Trp Asp Ile Asp Asn Glu Phe 
            660                 665                 670         


<210>  1244
<211>  50
<212>  PRT
<213>  Homo Sapiens

<400>  1244

Val Val Ser His Phe Asn Asp Cys Pro Asp Ser His Thr Gln Phe Cys 
1               5                   10                  15      


Phe His Gly Thr Cys Arg Phe Leu Val Gln Glu Asp Lys Pro Ala Cys 
            20                  25                  30          


Val Cys His Ser Gly Tyr Val Gly Ala Arg Cys Glu His Ala Asp Leu 
        35                  40                  45              


Leu Ala 
    50  


<210>  1245
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  1245

Ala Leu Asp Thr Asn Tyr Cys Phe Ser Ser Thr Glu Lys Asn Cys Cys 
1               5                   10                  15      


Val Arg Gln Leu Tyr Ile Asp Phe Arg Lys Asp Leu Gly Trp Lys Trp 
            20                  25                  30          


Ile His Glu Pro Lys Gly Tyr His Ala Asn Phe Cys Leu Gly Pro Cys 
        35                  40                  45              


Pro Tyr Ile Trp Ser Leu Asp Thr Gln Tyr Ser Lys Val Leu Ala Leu 
    50                  55                  60                  


Tyr Asn Gln His Asn Pro Gly Ala Ser Ala Ala Pro Cys Cys Val Pro 
65                  70                  75                  80  


Gln Ala Leu Glu Pro Leu Pro Ile Val Tyr Tyr Val Gly Arg Lys Pro 
                85                  90                  95      


Lys Val Glu Gln Leu Ser Asn Met Ile Val Arg Ser Cys Lys Cys Ser 
            100                 105                 110         


<210>  1246
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  1246

Ala Leu Asp Ala Ala Tyr Cys Phe Arg Asn Val Gln Asp Asn Cys Cys 
1               5                   10                  15      


Leu Arg Pro Leu Tyr Ile Asp Phe Lys Arg Asp Leu Gly Trp Lys Trp 
            20                  25                  30          


Ile His Glu Pro Lys Gly Tyr Asn Ala Asn Phe Cys Ala Gly Ala Cys 
        35                  40                  45              


Pro Tyr Leu Trp Ser Ser Asp Thr Gln His Ser Arg Val Leu Ser Leu 
    50                  55                  60                  


Tyr Asn Thr Ile Asn Pro Glu Ala Ser Ala Ser Pro Cys Cys Val Ser 
65                  70                  75                  80  


Gln Asp Leu Glu Pro Leu Thr Ile Leu Tyr Tyr Ile Gly Lys Thr Pro 
                85                  90                  95      


Lys Ile Glu Gln Leu Ser Asn Met Ile Val Lys Ser Cys Lys Cys Ser 
            100                 105                 110         


<210>  1247
<211>  277
<212>  PRT
<213>  Homo Sapiens

<400>  1247

Leu Ser Thr Cys Thr Thr Leu Asp Phe Gly His Ile Lys Lys Lys Arg 
1               5                   10                  15      


Val Glu Ala Ile Arg Gly Gln Ile Leu Ser Lys Leu Arg Leu Thr Ser 
            20                  25                  30          


Pro Pro Glu Pro Thr Val Met Thr His Val Pro Tyr Gln Val Leu Ala 
        35                  40                  45              


Leu Tyr Asn Ser Thr Arg Glu Leu Leu Glu Glu Met His Gly Glu Arg 
    50                  55                  60                  


Glu Glu Gly Cys Thr Gln Glu Asn Thr Glu Ser Glu Tyr Tyr Ala Lys 
65                  70                  75                  80  


Glu Ile His Lys Phe Asp Met Ile Gln Gly Leu Ala Glu His Asn Glu 
                85                  90                  95      


Leu Ala Val Cys Pro Lys Gly Ile Thr Ser Lys Val Phe Arg Phe Asn 
            100                 105                 110         


Val Ser Ser Val Glu Lys Asn Arg Thr Asn Leu Phe Arg Ala Glu Phe 
        115                 120                 125             


Arg Val Leu Arg Val Pro Asn Pro Ser Ser Lys Arg Asn Glu Gln Arg 
    130                 135                 140                 


Ile Glu Leu Phe Gln Ile Leu Arg Pro Asp Glu His Ile Ala Lys Gln 
145                 150                 155                 160 


Arg Tyr Ile Gly Gly Lys Asn Leu Pro Thr Arg Gly Thr Ala Glu Trp 
                165                 170                 175     


Leu Ser Phe Asp Val Thr Asp Thr Val Arg Glu Trp Leu Leu Arg Arg 
            180                 185                 190         


Glu Ser Asn Leu Gly Leu Glu Ile Ser Ile His Cys Pro Cys His Thr 
        195                 200                 205             


Phe Gln Pro Asn Gly Asp Ile Leu Glu Asn Ile His Glu Val Met Glu 
    210                 215                 220                 


Ile Lys Phe Lys Gly Val Asp Asn Glu Asp Asp His Gly Arg Gly Asp 
225                 230                 235                 240 


Leu Gly Arg Leu Lys Lys Gln Lys Asp His His Asn Pro His Leu Ile 
                245                 250                 255     


Leu Met Met Ile Pro Pro His Arg Leu Asp Asn Pro Gly Gln Gly Gly 
            260                 265                 270         


Gln Arg Lys Lys Arg 
        275         


<210>  1248
<211>  660
<212>  PRT
<213>  Homo Sapiens

<400>  1248

Gly Pro Ala Lys Ser Pro Tyr Gln Leu Val Leu Gln His Ser Arg Leu 
1               5                   10                  15      


Arg Gly Arg Gln His Gly Pro Asn Val Cys Ala Val Gln Lys Val Ile 
            20                  25                  30          


Gly Thr Asn Arg Lys Tyr Phe Thr Asn Cys Lys Gln Trp Tyr Gln Arg 
        35                  40                  45              


Lys Ile Cys Gly Lys Ser Thr Val Ile Ser Tyr Glu Cys Cys Pro Gly 
    50                  55                  60                  


Tyr Glu Lys Val Pro Gly Glu Lys Gly Cys Pro Ala Ala Leu Pro Leu 
65                  70                  75                  80  


Ser Asn Leu Tyr Glu Thr Leu Gly Val Val Gly Ser Thr Thr Thr Gln 
                85                  90                  95      


Leu Tyr Thr Asp Arg Thr Glu Lys Leu Arg Pro Glu Met Glu Gly Pro 
            100                 105                 110         


Gly Ser Phe Thr Ile Phe Ala Pro Ser Asn Glu Ala Trp Ala Ser Leu 
        115                 120                 125             


Pro Ala Glu Val Leu Asp Ser Leu Val Ser Asn Val Asn Ile Glu Leu 
    130                 135                 140                 


Leu Asn Ala Leu Arg Tyr His Met Val Gly Arg Arg Val Leu Thr Asp 
145                 150                 155                 160 


Glu Leu Lys His Gly Met Thr Leu Thr Ser Met Tyr Gln Asn Ser Asn 
                165                 170                 175     


Ile Gln Ile His His Tyr Pro Asn Gly Ile Val Thr Val Asn Cys Ala 
            180                 185                 190         


Arg Leu Leu Lys Ala Asp His His Ala Thr Asn Gly Val Val His Leu 
        195                 200                 205             


Ile Asp Lys Val Ile Ser Thr Ile Thr Asn Asn Ile Gln Gln Ile Ile 
    210                 215                 220                 


Glu Ile Glu Asp Thr Phe Glu Thr Leu Arg Ala Ala Val Ala Ala Ser 
225                 230                 235                 240 


Gly Leu Asn Thr Met Leu Glu Gly Asn Gly Gln Tyr Thr Leu Leu Ala 
                245                 250                 255     


Pro Thr Asn Glu Ala Phe Glu Lys Ile Pro Ser Glu Thr Leu Asn Arg 
            260                 265                 270         


Ile Leu Gly Asp Pro Glu Ala Leu Arg Asp Leu Leu Asn Asn His Ile 
        275                 280                 285             


Leu Lys Ser Ala Met Cys Ala Glu Ala Ile Val Ala Gly Leu Ser Val 
    290                 295                 300                 


Glu Thr Leu Glu Gly Thr Thr Leu Glu Val Gly Cys Ser Gly Asp Met 
305                 310                 315                 320 


Leu Thr Ile Asn Gly Lys Ala Ile Ile Ser Asn Lys Asp Ile Leu Ala 
                325                 330                 335     


Thr Asn Gly Val Ile His Tyr Ile Asp Glu Leu Leu Ile Pro Asp Ser 
            340                 345                 350         


Ala Lys Thr Leu Phe Glu Leu Ala Ala Glu Ser Asp Val Ser Thr Ala 
        355                 360                 365             


Ile Asp Leu Phe Arg Gln Ala Gly Leu Gly Asn His Leu Ser Gly Ser 
    370                 375                 380                 


Glu Arg Leu Thr Leu Leu Ala Pro Leu Asn Ser Val Phe Lys Asp Gly 
385                 390                 395                 400 


Thr Pro Pro Ile Asp Ala His Thr Arg Asn Leu Leu Arg Asn His Ile 
                405                 410                 415     


Ile Lys Asp Gln Leu Ala Ser Lys Tyr Leu Tyr His Gly Gln Thr Leu 
            420                 425                 430         


Glu Thr Leu Gly Gly Lys Lys Leu Arg Val Phe Val Tyr Arg Asn Ser 
        435                 440                 445             


Leu Cys Ile Glu Asn Ser Cys Ile Ala Ala His Asp Lys Arg Gly Arg 
    450                 455                 460                 


Tyr Gly Thr Leu Phe Thr Met Asp Arg Val Leu Thr Pro Pro Met Gly 
465                 470                 475                 480 


Thr Val Met Asp Val Leu Lys Gly Asp Asn Arg Phe Ser Met Leu Val 
                485                 490                 495     


Ala Ala Ile Gln Ser Ala Gly Leu Thr Glu Thr Leu Asn Arg Glu Gly 
            500                 505                 510         


Val Tyr Thr Val Phe Ala Pro Thr Asn Glu Ala Phe Arg Ala Leu Pro 
        515                 520                 525             


Pro Arg Glu Arg Ser Arg Leu Leu Gly Asp Ala Lys Glu Leu Ala Asn 
    530                 535                 540                 


Ile Leu Lys Tyr His Ile Gly Asp Glu Ile Leu Val Ser Gly Gly Ile 
545                 550                 555                 560 


Gly Ala Leu Val Arg Leu Lys Ser Leu Gln Gly Asp Lys Leu Glu Val 
                565                 570                 575     


Ser Leu Lys Asn Asn Val Val Ser Val Asn Lys Glu Pro Val Ala Glu 
            580                 585                 590         


Pro Asp Ile Met Ala Thr Asn Gly Val Val His Val Ile Thr Asn Val 
        595                 600                 605             


Leu Gln Pro Pro Ala Asn Arg Pro Gln Glu Arg Gly Asp Glu Leu Ala 
    610                 615                 620                 


Asp Ser Ala Leu Glu Ile Phe Lys Gln Ala Ser Ala Phe Ser Arg Ala 
625                 630                 635                 640 


Ser Gln Arg Ser Val Arg Leu Ala Pro Val Tyr Gln Lys Leu Leu Glu 
                645                 650                 655     


Arg Met Lys His 
            660 


<210>  1249
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1249

Leu Gln Cys Phe Cys His Leu Cys Thr Lys Asp Asn Phe Thr Cys Val 
1               5                   10                  15      


Thr Asp Gly Leu Cys Phe Val Ser Val Thr Glu Thr Thr Asp Lys Val 
            20                  25                  30          


Ile His Asn Ser Met Cys Ile Ala Glu Ile Asp Leu Ile Pro Arg Asp 
        35                  40                  45              


Arg Pro Phe Val Cys Ala Pro Ser Ser Lys Thr Gly Ser Val Thr Thr 
    50                  55                  60                  


Thr Tyr Cys Cys Asn Gln Asp His Cys Asn Lys Ile Glu Leu Pro Thr 
65                  70                  75                  80  


Thr Val Lys Ser Ser Pro Gly Leu Gly Pro Val Glu Leu 
                85                  90              


<210>  1250
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  1250

Thr Ile Pro Pro His Val Gln Lys Ser Asp Val Glu Met Glu Ala Gln 
1               5                   10                  15      


Lys Asp Glu Ile Ile Cys Pro Ser Cys Asn Arg Thr Ala His Pro Leu 
            20                  25                  30          


Arg His Ile Asn Asn Asp Met Ile Val Thr Asp Asn Asn Gly Ala Val 
        35                  40                  45              


Lys Phe Pro Gln Leu Cys Lys Phe Cys Asp Val Arg Phe Ser Thr Cys 
    50                  55                  60                  


Asp Asn Gln Lys Ser Cys Met Ser Asn Cys Ser Ile Thr Ser Ile Cys 
65                  70                  75                  80  


Glu Lys Pro Gln Glu Val Cys Val Ala Val Trp Arg Lys Asn Asp Glu 
                85                  90                  95      


Asn Ile Thr Leu Glu Thr Val Cys His Asp Pro Lys Leu Pro Tyr His 
            100                 105                 110         


Asp Phe Ile Leu Glu Asp Ala Ala Ser Pro Lys Cys Ile Met Lys Glu 
        115                 120                 125             


Lys Lys Lys Pro Gly Glu Thr Phe Phe Met Cys Ser Cys Ser Ser Asp 
    130                 135                 140                 


Glu Cys Asn Asp Asn Ile Ile Phe Ser Glu Glu Tyr Asn Thr Ser Asn 
145                 150                 155                 160 


Pro Asp Leu Leu Leu Val Ile Phe Gln 
                165                 


<210>  1251
<211>  767
<212>  PRT
<213>  Homo Sapiens

<400>  1251

Gly Pro Glu Pro Gly Ala Leu Cys Glu Leu Ser Pro Val Ser Ala Ser 
1               5                   10                  15      


His Pro Val Gln Ala Leu Met Glu Ser Phe Thr Val Leu Ser Gly Cys 
            20                  25                  30          


Ala Ser Arg Gly Thr Thr Gly Leu Pro Gln Glu Val His Val Leu Asn 
        35                  40                  45              


Leu Arg Thr Ala Gly Gln Gly Pro Gly Gln Leu Gln Arg Glu Val Thr 
    50                  55                  60                  


Leu His Leu Asn Pro Ile Ser Ser Val His Ile His His Lys Ser Val 
65                  70                  75                  80  


Val Phe Leu Leu Asn Ser Pro His Pro Leu Val Trp His Leu Lys Thr 
                85                  90                  95      


Glu Arg Leu Ala Thr Gly Val Ser Arg Leu Phe Leu Val Ser Glu Gly 
            100                 105                 110         


Ser Val Val Gln Phe Ser Ser Ala Asn Phe Ser Leu Thr Ala Glu Thr 
        115                 120                 125             


Glu Glu Arg Asn Phe Pro His Gly Asn Glu His Leu Leu Asn Trp Ala 
    130                 135                 140                 


Arg Lys Glu Tyr Gly Ala Val Thr Ser Phe Thr Glu Leu Lys Ile Ala 
145                 150                 155                 160 


Arg Asn Ile Tyr Ile Lys Val Gly Glu Asp Gln Val Phe Pro Pro Lys 
                165                 170                 175     


Cys Asn Ile Gly Lys Asn Phe Leu Ser Leu Asn Tyr Leu Ala Glu Tyr 
            180                 185                 190         


Leu Gln Pro Lys Ala Ala Glu Gly Cys Val Met Ser Ser Gln Pro Gln 
        195                 200                 205             


Asn Glu Glu Val His Ile Ile Glu Leu Ile Thr Pro Asn Ser Asn Pro 
    210                 215                 220                 


Tyr Ser Ala Phe Gln Val Asp Ile Thr Ile Asp Ile Arg Pro Ser Gln 
225                 230                 235                 240 


Glu Asp Leu Glu Val Val Lys Asn Leu Ile Leu Ile Leu Lys Cys Lys 
                245                 250                 255     


Lys Ser Val Asn Trp Val Ile Lys Ser Phe Asp Val Lys Gly Ser Leu 
            260                 265                 270         


Lys Ile Ile Ala Pro Asn Ser Ile Gly Phe Gly Lys Glu Ser Glu Arg 
        275                 280                 285             


Ser Met Thr Met Thr Lys Ser Ile Arg Asp Asp Ile Pro Ser Thr Gln 
    290                 295                 300                 


Gly Asn Leu Val Lys Trp Ala Leu Asp Asn Gly Tyr Ser Pro Ile Thr 
305                 310                 315                 320 


Ser Tyr Thr Met Ala Pro Val Ala Asn Arg Phe His Leu Arg Leu Glu 
                325                 330                 335     


Asn Asn Ala Glu Glu Met Gly Asp Glu Glu Val His Thr Ile Pro Pro 
            340                 345                 350         


Glu Leu Arg Ile Leu Leu Asp Pro Gly Ala Leu Pro Ala Leu Gln Asn 
        355                 360                 365             


Pro Pro Ile Arg Gly Gly Glu Gly Gln Asn Gly Gly Leu Pro Phe Pro 
    370                 375                 380                 


Phe Pro Asp Ile Ser Arg Arg Val Trp Asn Glu Glu Gly Glu Asp Gly 
385                 390                 395                 400 


Leu Pro Arg Pro Lys Asp Pro Val Ile Pro Ser Ile Gln Leu Phe Pro 
                405                 410                 415     


Gly Leu Arg Glu Pro Glu Glu Val Gln Gly Ser Val Asp Ile Ala Leu 
            420                 425                 430         


Ser Val Lys Cys Asp Asn Glu Lys Met Ile Val Ala Val Glu Lys Asp 
        435                 440                 445             


Ser Phe Gln Ala Ser Gly Tyr Ser Gly Met Asp Val Thr Leu Leu Asp 
    450                 455                 460                 


Pro Thr Cys Lys Ala Lys Met Asn Gly Thr His Phe Val Leu Glu Ser 
465                 470                 475                 480 


Pro Leu Asn Gly Cys Gly Thr Arg Pro Arg Trp Ser Ala Leu Asp Gly 
                485                 490                 495     


Val Val Tyr Tyr Asn Ser Ile Val Ile Gln Val Pro Ala Leu Gly Asp 
            500                 505                 510         


Ser Ser Gly Trp Pro Asp Gly Tyr Glu Asp Leu Glu Ser Gly Asp Asn 
        515                 520                 525             


Gly Phe Pro Gly Asp Met Asp Glu Gly Asp Ala Ser Leu Phe Thr Arg 
    530                 535                 540                 


Pro Glu Ile Val Val Phe Asn Cys Ser Leu Gln Gln Val Arg Asn Pro 
545                 550                 555                 560 


Ser Ser Phe Gln Glu Gln Pro His Gly Asn Ile Thr Phe Asn Met Glu 
                565                 570                 575     


Leu Tyr Asn Thr Asp Leu Phe Leu Val Pro Ser Gln Gly Val Phe Ser 
            580                 585                 590         


Val Pro Glu Asn Gly His Val Tyr Val Glu Val Ser Val Thr Lys Ala 
        595                 600                 605             


Glu Gln Glu Leu Gly Phe Ala Ile Gln Thr Cys Phe Ile Ser Pro Tyr 
    610                 615                 620                 


Ser Asn Pro Asp Arg Met Ser His Tyr Thr Ile Ile Glu Asn Ile Cys 
625                 630                 635                 640 


Pro Lys Asp Glu Ser Val Lys Phe Tyr Ser Pro Lys Arg Val His Phe 
                645                 650                 655     


Pro Ile Pro Gln Ala Asp Met Asp Lys Lys Arg Phe Ser Phe Val Phe 
            660                 665                 670         


Lys Pro Val Phe Asn Thr Ser Leu Leu Phe Leu Gln Cys Glu Leu Thr 
        675                 680                 685             


Leu Cys Thr Lys Met Glu Lys His Pro Gln Lys Leu Pro Lys Cys Val 
    690                 695                 700                 


Pro Pro Asp Glu Ala Cys Thr Ser Leu Asp Ala Ser Ile Ile Trp Ala 
705                 710                 715                 720 


Met Met Gln Asn Lys Lys Thr Phe Thr Lys Pro Leu Ala Val Ile His 
                725                 730                 735     


His Glu Ala Glu Ser Lys Glu Lys Gly Pro Ser Met Lys Glu Pro Asn 
            740                 745                 750         


Pro Ile Ser Pro Pro Ile Phe His Gly Leu Asp Thr Leu Thr Val 
        755                 760                 765         


<210>  1252
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  1252

Ala Pro Ala Glu Pro Gln Pro Gly Gly Ser Gln Cys Val Glu His Asp 
1               5                   10                  15      


Cys Phe Ala Leu Tyr Pro Gly Pro Ala Thr Phe Leu Asn Ala Ser Gln 
            20                  25                  30          


Ile Cys Asp Gly Leu Arg Gly His Leu Met Thr Val Arg Ser Ser Val 
        35                  40                  45              


Ala Ala Asp Val Ile Ser Leu Leu Leu Asn Gly Asp Gly Gly Val Gly 
    50                  55                  60                  


Arg Arg Arg Leu Trp Ile Gly Leu Gln Leu Pro Pro Gly Cys Gly Asp 
65                  70                  75                  80  


Pro Lys Arg Leu Gly Pro Leu Arg Gly Phe Gln Trp Val Thr Gly Asp 
                85                  90                  95      


Asn Asn Thr Ser Tyr Ser Arg Trp Ala Arg Leu Asp Leu Asn Gly Ala 
            100                 105                 110         


Pro Leu Cys Gly Pro Leu Cys Val Ala Val Ser Ala Ala Glu Ala Thr 
        115                 120                 125             


Val Pro Ser Glu Pro Ile Trp Glu Glu Gln Gln Cys Glu Val Lys Ala 
    130                 135                 140                 


Asp Gly Phe Leu Cys Glu Phe His Phe Pro Ala Thr Cys Arg Pro Leu 
145                 150                 155                 160 


Ala Val Glu Pro Gly Ala Ala Ala Ala Ala Val Ser Ile Thr Tyr Gly 
                165                 170                 175     


Thr Pro Phe Ala Ala Arg Gly Ala Asp Phe Gln Ala Leu Pro Val Gly 
            180                 185                 190         


Ser Ser Ala Ala Val Ala Pro Leu Gly Leu Gln Leu Met Cys Thr Ala 
        195                 200                 205             


Pro Pro Gly Ala Val Gln Gly His Trp Ala Arg Glu Ala Pro Gly Ala 
    210                 215                 220                 


Trp Asp Cys Ser Val Glu Asn Gly Gly Cys Glu His Ala Cys Asn Ala 
225                 230                 235                 240 


Ile Pro Gly Ala Pro Arg Cys Gln Cys Pro Ala Gly Ala Ala Leu Gln 
                245                 250                 255     


Ala Asp Gly Arg Ser Cys Thr Ala Ser Ala Thr Gln Ser Cys Asn Asp 
            260                 265                 270         


Leu Cys Glu His Phe Cys Val Pro Asn Pro Asp Gln Pro Gly Ser Tyr 
        275                 280                 285             


Ser Cys Met Cys Glu Thr Gly Tyr Arg Leu Ala Ala Asp Gln His Arg 
    290                 295                 300                 


Cys Glu Asp Val Asp Asp Cys Ile Leu Glu Pro Ser Pro Cys Pro Gln 
305                 310                 315                 320 


Arg Cys Val Asn Thr Gln Gly Gly Phe Glu Cys His Cys Tyr Pro Asn 
                325                 330                 335     


Tyr Asp Leu Val Asp Gly Glu Cys Val Glu Pro Val Asp Pro Cys Phe 
            340                 345                 350         


Arg Ala Asn Cys Glu Tyr Gln Cys Gln Pro Leu Asn Gln Thr Ser Tyr 
        355                 360                 365             


Leu Cys Val Cys Ala Glu Gly Phe Ala Pro Ile Pro His Glu Pro His 
    370                 375                 380                 


Arg Cys Gln Met Phe Cys Asn Gln Thr Ala Cys Pro Ala Asp Cys Asp 
385                 390                 395                 400 


Pro Asn Thr Gln Ala Ser Cys Glu Cys Pro Glu Gly Tyr Ile Leu Asp 
                405                 410                 415     


Asp Gly Phe Ile Cys Thr Asp Ile Asp Glu Cys Glu Asn Gly Gly Phe 
            420                 425                 430         


Cys Ser Gly Val Cys His Asn Leu Pro Gly Thr Phe Glu Cys Ile Cys 
        435                 440                 445             


Gly Pro Asp Ser Ala Leu Ala Arg His Ile Gly Thr Asp Cys Asp Ser 
    450                 455                 460                 


Gly Lys Val Asp Gly Gly Asp Ser Gly Ser Gly Glu Pro Pro Pro Ser 
465                 470                 475                 480 


Pro Thr Pro Gly Ser Thr Leu Thr Pro Pro Ala Val Gly Leu Val His 
                485                 490                 495     


Ser 
    


<210>  1253
<211>  1152
<212>  PRT
<213>  Homo Sapiens

<400>  1253

Asn Arg Ile Pro Glu Ser Gly Gly Asp Asn Ser Val Phe Asp Ile Phe 
1               5                   10                  15      


Glu Leu Thr Gly Ala Ala Arg Lys Gly Ser Gly Arg Arg Leu Val Lys 
            20                  25                  30          


Gly Pro Asp Pro Ser Ser Pro Ala Phe Arg Ile Glu Asp Ala Asn Leu 
        35                  40                  45              


Ile Pro Pro Val Pro Asp Asp Lys Phe Gln Asp Leu Val Asp Ala Val 
    50                  55                  60                  


Arg Ala Glu Lys Gly Phe Leu Leu Leu Ala Ser Leu Arg Gln Met Lys 
65                  70                  75                  80  


Lys Thr Arg Gly Thr Leu Leu Ala Leu Glu Arg Lys Asp His Ser Gly 
                85                  90                  95      


Gln Val Phe Ser Val Val Ser Asn Gly Lys Ala Gly Thr Leu Asp Leu 
            100                 105                 110         


Ser Leu Thr Val Gln Gly Lys Gln His Val Val Ser Val Glu Glu Ala 
        115                 120                 125             


Leu Leu Ala Thr Gly Gln Trp Lys Ser Ile Thr Leu Phe Val Gln Glu 
    130                 135                 140                 


Asp Arg Ala Gln Leu Tyr Ile Asp Cys Glu Lys Met Glu Asn Ala Glu 
145                 150                 155                 160 


Leu Asp Val Pro Ile Gln Ser Val Phe Thr Arg Asp Leu Ala Ser Ile 
                165                 170                 175     


Ala Arg Leu Arg Ile Ala Lys Gly Gly Val Asn Asp Asn Phe Gln Gly 
            180                 185                 190         


Val Leu Gln Asn Val Arg Phe Val Phe Gly Thr Thr Pro Glu Asp Ile 
        195                 200                 205             


Leu Arg Asn Lys Gly Cys Ser Ser Ser Thr Ser Val Leu Leu Thr Leu 
    210                 215                 220                 


Asp Asn Asn Val Val Asn Gly Ser Ser Pro Ala Ile Arg Thr Asn Tyr 
225                 230                 235                 240 


Ile Gly His Lys Thr Lys Asp Leu Gln Ala Ile Cys Gly Ile Ser Cys 
                245                 250                 255     


Asp Glu Leu Ser Ser Met Val Leu Glu Leu Arg Gly Leu Arg Thr Ile 
            260                 265                 270         


Val Thr Thr Leu Gln Asp Ser Ile Arg Lys Val Thr Glu Glu Asn Lys 
        275                 280                 285             


Glu Leu Ala Asn Glu Leu Arg Arg Pro Pro Leu Cys Tyr His Asn Gly 
    290                 295                 300                 


Val Gln Tyr Arg Asn Asn Glu Glu Trp Thr Val Asp Ser Cys Thr Glu 
305                 310                 315                 320 


Cys His Cys Gln Asn Ser Val Thr Ile Cys Lys Lys Val Ser Cys Pro 
                325                 330                 335     


Ile Met Pro Cys Ser Asn Ala Thr Val Pro Asp Gly Glu Cys Cys Pro 
            340                 345                 350         


Arg Cys Trp Pro Ser Asp Ser Ala Asp Asp Gly Trp Ser Pro Trp Ser 
        355                 360                 365             


Glu Trp Thr Ser Cys Ser Thr Ser Cys Gly Asn Gly Ile Gln Gln Arg 
    370                 375                 380                 


Gly Arg Ser Cys Asp Ser Leu Asn Asn Arg Cys Glu Gly Ser Ser Val 
385                 390                 395                 400 


Gln Thr Arg Thr Cys His Ile Gln Glu Cys Asp Lys Arg Phe Lys Gln 
                405                 410                 415     


Asp Gly Gly Trp Ser His Trp Ser Pro Trp Ser Ser Cys Ser Val Thr 
            420                 425                 430         


Cys Gly Asp Gly Val Ile Thr Arg Ile Arg Leu Cys Asn Ser Pro Ser 
        435                 440                 445             


Pro Gln Met Asn Gly Lys Pro Cys Glu Gly Glu Ala Arg Glu Thr Lys 
    450                 455                 460                 


Ala Cys Lys Lys Asp Ala Cys Pro Ile Asn Gly Gly Trp Gly Pro Trp 
465                 470                 475                 480 


Ser Pro Trp Asp Ile Cys Ser Val Thr Cys Gly Gly Gly Val Gln Lys 
                485                 490                 495     


Arg Ser Arg Leu Cys Asn Asn Pro Thr Pro Gln Phe Gly Gly Lys Asp 
            500                 505                 510         


Cys Val Gly Asp Val Thr Glu Asn Gln Ile Cys Asn Lys Gln Asp Cys 
        515                 520                 525             


Pro Ile Asp Gly Cys Leu Ser Asn Pro Cys Phe Ala Gly Val Lys Cys 
    530                 535                 540                 


Thr Ser Tyr Pro Asp Gly Ser Trp Lys Cys Gly Ala Cys Pro Pro Gly 
545                 550                 555                 560 


Tyr Ser Gly Asn Gly Ile Gln Cys Thr Asp Val Asp Glu Cys Lys Glu 
                565                 570                 575     


Val Pro Asp Ala Cys Phe Asn His Asn Gly Glu His Arg Cys Glu Asn 
            580                 585                 590         


Thr Asp Pro Gly Tyr Asn Cys Leu Pro Cys Pro Pro Arg Phe Thr Gly 
        595                 600                 605             


Ser Gln Pro Phe Gly Gln Gly Val Glu His Ala Thr Ala Asn Lys Gln 
    610                 615                 620                 


Val Cys Lys Pro Arg Asn Pro Cys Thr Asp Gly Thr His Asp Cys Asn 
625                 630                 635                 640 


Lys Asn Ala Lys Cys Asn Tyr Leu Gly His Tyr Ser Asp Pro Met Tyr 
                645                 650                 655     


Arg Cys Glu Cys Lys Pro Gly Tyr Ala Gly Asn Gly Ile Ile Cys Gly 
            660                 665                 670         


Glu Asp Thr Asp Leu Asp Gly Trp Pro Asn Glu Asn Leu Val Cys Val 
        675                 680                 685             


Ala Asn Ala Thr Tyr His Cys Lys Lys Asp Asn Cys Pro Asn Leu Pro 
    690                 695                 700                 


Asn Ser Gly Gln Glu Asp Tyr Asp Lys Asp Gly Ile Gly Asp Ala Cys 
705                 710                 715                 720 


Asp Asp Asp Asp Asp Asn Asp Lys Ile Pro Asp Asp Arg Asp Asn Cys 
                725                 730                 735     


Pro Phe His Tyr Asn Pro Ala Gln Tyr Asp Tyr Asp Arg Asp Asp Val 
            740                 745                 750         


Gly Asp Arg Cys Asp Asn Cys Pro Tyr Asn His Asn Pro Asp Gln Ala 
        755                 760                 765             


Asp Thr Asp Asn Asn Gly Glu Gly Asp Ala Cys Ala Ala Asp Ile Asp 
    770                 775                 780                 


Gly Asp Gly Ile Leu Asn Glu Arg Asp Asn Cys Gln Tyr Val Tyr Asn 
785                 790                 795                 800 


Val Asp Gln Arg Asp Thr Asp Met Asp Gly Val Gly Asp Gln Cys Asp 
                805                 810                 815     


Asn Cys Pro Leu Glu His Asn Pro Asp Gln Leu Asp Ser Asp Ser Asp 
            820                 825                 830         


Arg Ile Gly Asp Thr Cys Asp Asn Asn Gln Asp Ile Asp Glu Asp Gly 
        835                 840                 845             


His Gln Asn Asn Leu Asp Asn Cys Pro Tyr Val Pro Asn Ala Asn Gln 
    850                 855                 860                 


Ala Asp His Asp Lys Asp Gly Lys Gly Asp Ala Cys Asp His Asp Asp 
865                 870                 875                 880 


Asp Asn Asp Gly Ile Pro Asp Asp Lys Asp Asn Cys Arg Leu Val Pro 
                885                 890                 895     


Asn Pro Asp Gln Lys Asp Ser Asp Gly Asp Gly Arg Gly Asp Ala Cys 
            900                 905                 910         


Lys Asp Asp Phe Asp His Asp Ser Val Pro Asp Ile Asp Asp Ile Cys 
        915                 920                 925             


Pro Glu Asn Val Asp Ile Ser Glu Thr Asp Phe Arg Arg Phe Gln Met 
    930                 935                 940                 


Ile Pro Leu Asp Pro Lys Gly Thr Ser Gln Asn Asp Pro Asn Trp Val 
945                 950                 955                 960 


Val Arg His Gln Gly Lys Glu Leu Val Gln Thr Val Asn Cys Asp Pro 
                965                 970                 975     


Gly Leu Ala Val Gly Tyr Asp Glu Phe Asn Ala Val Asp Phe Ser Gly 
            980                 985                 990         


Thr Phe Phe Ile Asn Thr Glu Arg  Asp Asp Asp Tyr Ala  Gly Phe Val 
        995                 1000                 1005             


Phe Gly  Tyr Gln Ser Ser Ser  Arg Phe Tyr Val Val  Met Trp Lys 
    1010                 1015                 1020             


Gln Val  Thr Gln Ser Tyr Trp  Asp Thr Asn Pro Thr  Arg Ala Gln 
    1025                 1030                 1035             


Gly Tyr  Ser Gly Leu Ser Val  Lys Val Val Asn Ser  Thr Thr Gly 
    1040                 1045                 1050             


Pro Gly  Glu His Leu Arg Asn  Ala Leu Trp His Thr  Gly Asn Thr 
    1055                 1060                 1065             


Pro Gly  Gln Val Arg Thr Leu  Trp His Asp Pro Arg  His Ile Gly 
    1070                 1075                 1080             


Trp Lys  Asp Phe Thr Ala Tyr  Arg Trp Arg Leu Ser  His Arg Pro 
    1085                 1090                 1095             


Lys Thr  Gly Phe Ile Arg Val  Val Met Tyr Glu Gly  Lys Lys Ile 
    1100                 1105                 1110             


Met Ala  Asp Ser Gly Pro Ile  Tyr Asp Lys Thr Tyr  Ala Gly Gly 
    1115                 1120                 1125             


Arg Leu  Gly Leu Phe Val Phe  Ser Gln Glu Met Val  Phe Phe Ser 
    1130                 1135                 1140             


Asp Leu  Lys Tyr Glu Cys Arg  Asp Pro 
    1145                 1150         


<210>  1254
<211>  1154
<212>  PRT
<213>  Homo Sapiens

<400>  1254

Gly His Gln Asp Lys Asp Thr Thr Phe Asp Leu Phe Ser Ile Ser Asn 
1               5                   10                  15      


Ile Asn Arg Lys Thr Ile Gly Ala Lys Gln Phe Arg Gly Pro Asp Pro 
            20                  25                  30          


Gly Val Pro Ala Tyr Arg Phe Val Arg Phe Asp Tyr Ile Pro Pro Val 
        35                  40                  45              


Asn Ala Asp Asp Leu Ser Lys Ile Thr Lys Ile Met Arg Gln Lys Glu 
    50                  55                  60                  


Gly Phe Phe Leu Thr Ala Gln Leu Lys Gln Asp Gly Lys Ser Arg Gly 
65                  70                  75                  80  


Thr Leu Leu Ala Leu Glu Gly Pro Gly Leu Ser Gln Arg Gln Phe Glu 
                85                  90                  95      


Ile Val Ser Asn Gly Pro Ala Asp Thr Leu Asp Leu Thr Tyr Trp Ile 
            100                 105                 110         


Asp Gly Thr Arg His Val Val Ser Leu Glu Asp Val Gly Leu Ala Asp 
        115                 120                 125             


Ser Gln Trp Lys Asn Val Thr Val Gln Val Ala Gly Glu Thr Tyr Ser 
    130                 135                 140                 


Leu His Val Gly Cys Asp Leu Ile Asp Ser Phe Ala Leu Asp Glu Pro 
145                 150                 155                 160 


Phe Tyr Glu His Leu Gln Ala Glu Lys Ser Arg Met Tyr Val Ala Lys 
                165                 170                 175     


Gly Ser Ala Arg Glu Ser His Phe Arg Gly Leu Leu Gln Asn Val His 
            180                 185                 190         


Leu Val Phe Glu Asn Ser Val Glu Asp Ile Leu Ser Lys Lys Gly Cys 
        195                 200                 205             


Gln Gln Gly Gln Gly Ala Glu Ile Asn Ala Ile Ser Glu Asn Thr Glu 
    210                 215                 220                 


Thr Leu Arg Leu Gly Pro His Val Thr Thr Glu Tyr Val Gly Pro Ser 
225                 230                 235                 240 


Ser Glu Arg Arg Pro Glu Val Cys Glu Arg Ser Cys Glu Glu Leu Gly 
                245                 250                 255     


Asn Met Val Gln Glu Leu Ser Gly Leu His Val Leu Val Asn Gln Leu 
            260                 265                 270         


Ser Glu Asn Leu Lys Arg Val Ser Asn Asp Asn Gln Phe Leu Trp Glu 
        275                 280                 285             


Leu Ile Gly Gly Pro Pro Lys Thr Arg Asn Met Ser Ala Cys Trp Gln 
    290                 295                 300                 


Asp Gly Arg Phe Phe Ala Glu Asn Glu Thr Trp Val Val Asp Ser Cys 
305                 310                 315                 320 


Thr Thr Cys Thr Cys Lys Lys Phe Lys Thr Ile Cys His Gln Ile Thr 
                325                 330                 335     


Cys Pro Pro Ala Thr Cys Ala Ser Pro Ser Phe Val Glu Gly Glu Cys 
            340                 345                 350         


Cys Pro Ser Cys Leu His Ser Val Asp Gly Glu Glu Gly Trp Ser Pro 
        355                 360                 365             


Trp Ala Glu Trp Thr Gln Cys Ser Val Thr Cys Gly Ser Gly Thr Gln 
    370                 375                 380                 


Gln Arg Gly Arg Ser Cys Asp Val Thr Ser Asn Thr Cys Leu Gly Pro 
385                 390                 395                 400 


Ser Ile Gln Thr Arg Ala Cys Ser Leu Ser Lys Cys Asp Thr Arg Ile 
                405                 410                 415     


Arg Gln Asp Gly Gly Trp Ser His Trp Ser Pro Trp Ser Ser Cys Ser 
            420                 425                 430         


Val Thr Cys Gly Val Gly Asn Ile Thr Arg Ile Arg Leu Cys Asn Ser 
        435                 440                 445             


Pro Val Pro Gln Met Gly Gly Lys Asn Cys Lys Gly Ser Gly Arg Glu 
    450                 455                 460                 


Thr Lys Ala Cys Gln Gly Ala Pro Cys Pro Ile Asp Gly Arg Trp Ser 
465                 470                 475                 480 


Pro Trp Ser Pro Trp Ser Ala Cys Thr Val Thr Cys Ala Gly Gly Ile 
                485                 490                 495     


Arg Glu Arg Thr Arg Val Cys Asn Ser Pro Glu Pro Gln Tyr Gly Gly 
            500                 505                 510         


Lys Ala Cys Val Gly Asp Val Gln Glu Arg Gln Met Cys Asn Lys Arg 
        515                 520                 525             


Ser Cys Pro Val Asp Gly Cys Leu Ser Asn Pro Cys Phe Pro Gly Ala 
    530                 535                 540                 


Gln Cys Ser Ser Phe Pro Asp Gly Ser Trp Ser Cys Gly Ser Cys Pro 
545                 550                 555                 560 


Val Gly Phe Leu Gly Asn Gly Thr His Cys Glu Asp Leu Asp Glu Cys 
                565                 570                 575     


Ala Leu Val Pro Asp Ile Cys Phe Ser Thr Ser Lys Val Pro Arg Cys 
            580                 585                 590         


Val Asn Thr Gln Pro Gly Phe His Cys Leu Pro Cys Pro Pro Arg Tyr 
        595                 600                 605             


Arg Gly Asn Gln Pro Val Gly Val Gly Leu Glu Ala Ala Lys Thr Glu 
    610                 615                 620                 


Lys Gln Val Cys Glu Pro Glu Asn Pro Cys Lys Asp Lys Thr His Asn 
625                 630                 635                 640 


Cys His Lys His Ala Glu Cys Ile Tyr Leu Gly His Phe Ser Asp Pro 
                645                 650                 655     


Met Tyr Lys Cys Glu Cys Gln Thr Gly Tyr Ala Gly Asp Gly Leu Ile 
            660                 665                 670         


Cys Gly Glu Asp Ser Asp Leu Asp Gly Trp Pro Asn Leu Asn Leu Val 
        675                 680                 685             


Cys Ala Thr Asn Ala Thr Tyr His Cys Ile Lys Asp Asn Cys Pro His 
    690                 695                 700                 


Leu Pro Asn Ser Gly Gln Glu Asp Phe Asp Lys Asp Gly Ile Gly Asp 
705                 710                 715                 720 


Ala Cys Asp Asp Asp Asp Asp Asn Asp Gly Val Thr Asp Glu Lys Asp 
                725                 730                 735     


Asn Cys Gln Leu Leu Phe Asn Pro Arg Gln Ala Asp Tyr Asp Lys Asp 
            740                 745                 750         


Glu Val Gly Asp Arg Cys Asp Asn Cys Pro Tyr Val His Asn Pro Ala 
        755                 760                 765             


Gln Ile Asp Thr Asp Asn Asn Gly Glu Gly Asp Ala Cys Ser Val Asp 
    770                 775                 780                 


Ile Asp Gly Asp Asp Val Phe Asn Glu Arg Asp Asn Cys Pro Tyr Val 
785                 790                 795                 800 


Tyr Asn Thr Asp Gln Arg Asp Thr Asp Gly Asp Gly Val Gly Asp His 
                805                 810                 815     


Cys Asp Asn Cys Pro Leu Val His Asn Pro Asp Gln Thr Asp Val Asp 
            820                 825                 830         


Asn Asp Leu Val Gly Asp Gln Cys Asp Asn Asn Glu Asp Ile Asp Asp 
        835                 840                 845             


Asp Gly His Gln Asn Asn Gln Asp Asn Cys Pro Tyr Ile Ser Asn Ala 
    850                 855                 860                 


Asn Gln Ala Asp His Asp Arg Asp Gly Gln Gly Asp Ala Cys Asp Pro 
865                 870                 875                 880 


Asp Asp Asp Asn Asp Gly Val Pro Asp Asp Arg Asp Asn Cys Arg Leu 
                885                 890                 895     


Val Phe Asn Pro Asp Gln Glu Asp Leu Asp Gly Asp Gly Arg Gly Asp 
            900                 905                 910         


Ile Cys Lys Asp Asp Phe Asp Asn Asp Asn Ile Pro Asp Ile Asp Asp 
        915                 920                 925             


Val Cys Pro Glu Asn Asn Ala Ile Ser Glu Thr Asp Phe Arg Asn Phe 
    930                 935                 940                 


Gln Met Val Pro Leu Asp Pro Lys Gly Thr Thr Gln Ile Asp Pro Asn 
945                 950                 955                 960 


Trp Val Ile Arg His Gln Gly Lys Glu Leu Val Gln Thr Ala Asn Ser 
                965                 970                 975     


Asp Pro Gly Ile Ala Val Gly Phe Asp Glu Phe Gly Ser Val Asp Phe 
            980                 985                 990         


Ser Gly Thr Phe Tyr Val Asn Thr  Asp Arg Asp Asp Asp  Tyr Ala Gly 
        995                 1000                 1005             


Phe Val  Phe Gly Tyr Gln Ser  Ser Ser Arg Phe Tyr  Val Val Met 
    1010                 1015                 1020             


Trp Lys  Gln Val Thr Gln Thr  Tyr Trp Glu Asp Gln  Pro Thr Arg 
    1025                 1030                 1035             


Ala Tyr  Gly Tyr Ser Gly Val  Ser Leu Lys Val Val  Asn Ser Thr 
    1040                 1045                 1050             


Thr Gly  Thr Gly Glu His Leu  Arg Asn Ala Leu Trp  His Thr Gly 
    1055                 1060                 1065             


Asn Thr  Pro Gly Gln Val Arg  Thr Leu Trp His Asp  Pro Arg Asn 
    1070                 1075                 1080             


Ile Gly  Trp Lys Asp Tyr Thr  Ala Tyr Arg Trp His  Leu Thr His 
    1085                 1090                 1095             


Arg Pro  Lys Thr Gly Tyr Ile  Arg Val Leu Val His  Glu Gly Lys 
    1100                 1105                 1110             


Gln Val  Met Ala Asp Ser Gly  Pro Ile Tyr Asp Gln  Thr Tyr Ala 
    1115                 1120                 1125             


Gly Gly  Arg Leu Gly Leu Phe  Val Phe Ser Gln Glu  Met Val Tyr 
    1130                 1135                 1140             


Phe Ser  Asp Leu Lys Tyr Glu  Cys Arg Asp Ile 
    1145                 1150                 


<210>  1255
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  1255

Thr Asp Thr Asp Ile Asp Gly Tyr Pro Asp Gln Ala Leu Pro Cys Met 
1               5                   10                  15      


Asp Asn Asn Lys His Cys Lys Gln Asp Asn Cys Leu Leu Thr Pro Asn 
            20                  25                  30          


Ser Gly Gln Glu Asp Ala Asp Asn Asp Gly Val Gly Asp Gln Cys Asp 
        35                  40                  45              


Asp Asp Ala Asp Gly Asp Gly Ile Lys Asn Val Glu Asp Asn Cys Arg 
    50                  55                  60                  


Leu Phe Pro Asn Lys Asp Gln Gln Asn Ser Asp Thr Asp Ser Phe Gly 
65                  70                  75                  80  


Asp Ala Cys Asp Asn Cys Pro Asn Val Pro Asn Asn Asp Gln Lys Asp 
                85                  90                  95      


Thr Asp Gly Asn Gly Glu Gly Asp Ala Cys Asp Asn Asp Val Asp Gly 
            100                 105                 110         


Asp Gly Ile Pro Asn Gly Leu Asp Asn Cys Pro Lys Val Pro Asn Pro 
        115                 120                 125             


Leu Gln Thr Asp Arg Asp Glu Asp Gly Val Gly Asp Ala Cys Asp Ser 
    130                 135                 140                 


Cys Pro Glu Met Ser Asn Pro Thr Gln Thr Asp Ala Asp Ser Asp Leu 
145                 150                 155                 160 


Val Gly Asp Val Cys Asp Thr Asn Glu Asp Ser Asp Gly Asp Gly His 
                165                 170                 175     


Gln Asp Thr Lys Asp Asn Cys Pro Gln Leu Pro Asn Ser Ser Gln Leu 
            180                 185                 190         


Asp Ser Asp Asn Asp Gly Leu Gly Asp Glu Cys Asp Gly Asp Asp Asp 
        195                 200                 205             


Asn Asp Gly Ile Pro Asp Tyr Val Pro Pro Gly Pro Asp Asn Cys Arg 
    210                 215                 220                 


Leu Val Pro Asn Pro Asn Gln Lys Asp Ser Asp Gly Asn Gly Val Gly 
225                 230                 235                 240 


Asp Val Cys Glu Asp Asp Phe Asp Asn Asp Ala Val Val Asp Pro Leu 
                245                 250                 255     


Asp Val Cys Pro Glu Ser Ala Glu Val Thr Leu Thr Asp Phe Arg Ala 
            260                 265                 270         


Tyr Gln Thr Val Val Leu Asp Pro Glu Gly Asp Ala Gln Ile Asp Pro 
        275                 280                 285             


Asn Trp Val Val Leu Asn Gln Gly Met Glu Ile Val Gln Thr Met Asn 
    290                 295                 300                 


Ser Asp Pro Gly Leu Ala Val Gly Tyr Thr Ala Phe Asn Gly Val Asp 
305                 310                 315                 320 


Phe Glu Gly Thr Phe His Val Asn Thr Val Thr Asp Asp Asp Tyr Ala 
                325                 330                 335     


Gly Phe Leu Phe Ser Tyr Gln Asp Ser Gly Arg Phe Tyr Val Val Met 
            340                 345                 350         


Trp Lys Gln Thr Glu Gln Thr Tyr Trp Gln Ala Thr Pro Phe Arg Ala 
        355                 360                 365             


Val Ala Gln Pro Gly Leu Gln Leu Lys Ala Val Thr Ser Val Ser Gly 
    370                 375                 380                 


Pro Gly Glu His Leu Arg Asn Ala Leu Trp His Thr Gly His Thr Pro 
385                 390                 395                 400 


Asp Gln Val Arg Leu Leu Trp Thr Asp Pro Arg Asn Val Gly Trp Arg 
                405                 410                 415     


Asp Lys Thr Ser Tyr Arg Trp Gln Leu Leu His Arg Pro Gln Val Gly 
            420                 425                 430         


Tyr Ile Arg Val Lys Leu Tyr Glu Gly Pro Gln Leu Val Ala Asp Ser 
        435                 440                 445             


Gly Val Ile Ile Asp Thr Ser Met Arg Gly Gly Arg Leu Gly Val Phe 
    450                 455                 460                 


Cys Phe Ser Gln Glu Asn Ile Ile Trp Ser Asn Leu Gln Tyr Arg Cys 
465                 470                 475                 480 


Asn Asp Thr Val Pro Glu Asp Phe Glu Pro Phe Arg Arg Gln Leu Leu 
                485                 490                 495     


Gln Gly Arg Val 
            500 


<210>  1256
<211>  935
<212>  PRT
<213>  Homo Sapiens

<400>  1256

Thr Pro Gln Val Phe Asp Leu Leu Pro Ser Ser Ser Gln Arg Leu Asn 
1               5                   10                  15      


Pro Gly Ala Leu Leu Pro Val Leu Thr Asp Pro Ala Leu Asn Asp Leu 
            20                  25                  30          


Tyr Val Ile Ser Thr Phe Lys Leu Gln Thr Lys Ser Ser Ala Thr Ile 
        35                  40                  45              


Phe Gly Leu Tyr Ser Ser Thr Asp Asn Ser Lys Tyr Phe Glu Phe Thr 
    50                  55                  60                  


Val Met Gly Arg Leu Asn Lys Ala Ile Leu Arg Tyr Leu Lys Asn Asp 
65                  70                  75                  80  


Gly Lys Val His Leu Val Val Phe Asn Asn Leu Gln Leu Ala Asp Gly 
                85                  90                  95      


Arg Arg His Arg Ile Leu Leu Arg Leu Ser Asn Leu Gln Arg Gly Ala 
            100                 105                 110         


Gly Ser Leu Glu Leu Tyr Leu Asp Cys Ile Gln Val Asp Ser Val His 
        115                 120                 125             


Asn Leu Pro Arg Ala Phe Ala Gly Pro Ser Gln Lys Pro Glu Thr Ile 
    130                 135                 140                 


Glu Leu Arg Thr Phe Gln Arg Lys Pro Gln Asp Phe Leu Glu Glu Leu 
145                 150                 155                 160 


Lys Leu Val Val Arg Gly Ser Leu Phe Gln Val Ala Ser Leu Gln Asp 
                165                 170                 175     


Cys Phe Leu Gln Gln Ser Glu Pro Leu Ala Ala Thr Gly Thr Gly Asp 
            180                 185                 190         


Phe Asn Arg Gln Phe Leu Gly Gln Met Thr Gln Leu Asn Gln Leu Leu 
        195                 200                 205             


Gly Glu Val Lys Asp Leu Leu Arg Gln Gln Val Lys Glu Thr Ser Phe 
    210                 215                 220                 


Leu Arg Asn Thr Ile Ala Glu Cys Gln Ala Cys Gly Pro Leu Lys Phe 
225                 230                 235                 240 


Gln Ser Pro Thr Pro Ser Thr Val Val Pro Pro Ala Pro Pro Ala Pro 
                245                 250                 255     


Pro Thr Arg Pro Pro Arg Arg Cys Asp Ser Asn Pro Cys Phe Arg Gly 
            260                 265                 270         


Val Gln Cys Thr Asp Ser Arg Asp Gly Phe Gln Cys Gly Pro Cys Pro 
        275                 280                 285             


Glu Gly Tyr Thr Gly Asn Gly Ile Thr Cys Ile Asp Val Asp Glu Cys 
    290                 295                 300                 


Lys Tyr His Pro Cys Tyr Pro Gly Val His Cys Ile Asn Leu Ser Pro 
305                 310                 315                 320 


Gly Phe Arg Cys Asp Ala Cys Pro Val Gly Phe Thr Gly Pro Met Val 
                325                 330                 335     


Gln Gly Val Gly Ile Ser Phe Ala Lys Ser Asn Lys Gln Val Cys Thr 
            340                 345                 350         


Asp Ile Asp Glu Cys Arg Asn Gly Ala Cys Val Pro Asn Ser Ile Cys 
        355                 360                 365             


Val Asn Thr Leu Gly Ser Tyr Arg Cys Gly Pro Cys Lys Pro Gly Tyr 
    370                 375                 380                 


Thr Gly Asp Gln Ile Arg Gly Cys Lys Ala Glu Arg Asn Cys Arg Asn 
385                 390                 395                 400 


Pro Glu Leu Asn Pro Cys Ser Val Asn Ala Gln Cys Ile Glu Glu Arg 
                405                 410                 415     


Gln Gly Asp Val Thr Cys Val Cys Gly Val Gly Trp Ala Gly Asp Gly 
            420                 425                 430         


Tyr Ile Cys Gly Lys Asp Val Asp Ile Asp Ser Tyr Pro Asp Glu Glu 
        435                 440                 445             


Leu Pro Cys Ser Ala Arg Asn Cys Lys Lys Asp Asn Cys Lys Tyr Val 
    450                 455                 460                 


Pro Asn Ser Gly Gln Glu Asp Ala Asp Arg Asp Gly Ile Gly Asp Ala 
465                 470                 475                 480 


Cys Asp Glu Asp Ala Asp Gly Asp Gly Ile Leu Asn Glu Gln Asp Asn 
                485                 490                 495     


Cys Val Leu Ile His Asn Val Asp Gln Arg Asn Ser Asp Lys Asp Ile 
            500                 505                 510         


Phe Gly Asp Ala Cys Asp Asn Cys Leu Ser Val Leu Asn Asn Asp Gln 
        515                 520                 525             


Lys Asp Thr Asp Gly Asp Gly Arg Gly Asp Ala Cys Asp Asp Asp Met 
    530                 535                 540                 


Asp Gly Asp Gly Ile Lys Asn Ile Leu Asp Asn Cys Pro Lys Phe Pro 
545                 550                 555                 560 


Asn Arg Asp Gln Arg Asp Lys Asp Gly Asp Gly Val Gly Asp Ala Cys 
                565                 570                 575     


Asp Ser Cys Pro Asp Val Ser Asn Pro Asn Gln Ser Asp Val Asp Asn 
            580                 585                 590         


Asp Leu Val Gly Asp Ser Cys Asp Thr Asn Gln Asp Ser Asp Gly Asp 
        595                 600                 605             


Gly His Gln Asp Ser Thr Asp Asn Cys Pro Thr Val Ile Asn Ser Ala 
    610                 615                 620                 


Gln Leu Asp Thr Asp Lys Asp Gly Ile Gly Asp Glu Cys Asp Asp Asp 
625                 630                 635                 640 


Asp Asp Asn Asp Gly Ile Pro Asp Leu Val Pro Pro Gly Pro Asp Asn 
                645                 650                 655     


Cys Arg Leu Val Pro Asn Pro Ala Gln Glu Asp Ser Asn Ser Asp Gly 
            660                 665                 670         


Val Gly Asp Ile Cys Glu Ser Asp Phe Asp Gln Asp Gln Val Ile Asp 
        675                 680                 685             


Arg Ile Asp Val Cys Pro Glu Asn Ala Glu Val Thr Leu Thr Asp Phe 
    690                 695                 700                 


Arg Ala Tyr Gln Thr Val Val Leu Asp Pro Glu Gly Asp Ala Gln Ile 
705                 710                 715                 720 


Asp Pro Asn Trp Val Val Leu Asn Gln Gly Met Glu Ile Val Gln Thr 
                725                 730                 735     


Met Asn Ser Asp Pro Gly Leu Ala Val Gly Tyr Thr Ala Phe Asn Gly 
            740                 745                 750         


Val Asp Phe Glu Gly Thr Phe His Val Asn Thr Gln Thr Asp Asp Asp 
        755                 760                 765             


Tyr Ala Gly Phe Ile Phe Gly Tyr Gln Asp Ser Ser Ser Phe Tyr Val 
    770                 775                 780                 


Val Met Trp Lys Gln Thr Glu Gln Thr Tyr Trp Gln Ala Thr Pro Phe 
785                 790                 795                 800 


Arg Ala Val Ala Glu Pro Gly Ile Gln Leu Lys Ala Val Lys Ser Lys 
                805                 810                 815     


Thr Gly Pro Gly Glu His Leu Arg Asn Ser Leu Trp His Thr Gly Asp 
            820                 825                 830         


Thr Ser Asp Gln Val Arg Leu Leu Trp Lys Asp Ser Arg Asn Val Gly 
        835                 840                 845             


Trp Lys Asp Lys Val Ser Tyr Arg Trp Phe Leu Gln His Arg Pro Gln 
    850                 855                 860                 


Val Gly Tyr Ile Arg Val Arg Phe Tyr Glu Gly Ser Glu Leu Val Ala 
865                 870                 875                 880 


Asp Ser Gly Val Thr Ile Asp Thr Thr Met Arg Gly Gly Arg Leu Gly 
                885                 890                 895     


Val Phe Cys Phe Ser Gln Glu Asn Ile Ile Trp Ser Asn Leu Lys Tyr 
            900                 905                 910         


Arg Cys Asn Asp Thr Ile Pro Glu Asp Phe Gln Glu Phe Gln Thr Gln 
        915                 920                 925             


Asn Phe Asp Arg Phe Asp Asn 
    930                 935 


<210>  1257
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  1257

Gln Lys Val Thr Ser Leu Thr Ala Cys Leu Val Asp Gln Ser Leu Arg 
1               5                   10                  15      


Leu Asp Cys Arg His Glu Asn Thr Ser Ser Ser Pro Ile Gln Tyr Glu 
            20                  25                  30          


Phe Ser Leu Thr Arg Glu Thr Lys Lys His Val Leu Phe Gly Thr Val 
        35                  40                  45              


Gly Val Pro Glu His Thr Tyr Arg Ser Arg Thr Asn Phe Thr Ser Lys 
    50                  55                  60                  


Tyr Asn Met Lys Val Leu Tyr Leu Ser Ala Phe Thr Ser Lys Asp Glu 
65                  70                  75                  80  


Gly Thr Tyr Thr Cys Ala Leu His His Ser Gly His Ser Pro Pro Ile 
                85                  90                  95      


Ser Ser Gln Asn Val Thr Val Leu Arg Asp Lys Leu Val Lys Cys 
            100                 105                 110     


<210>  1258
<211>  738
<212>  PRT
<213>  Homo Sapiens

<400>  1258

Ala Val Asp Leu Thr Leu Leu Ala Asn Leu Arg Leu Thr Asp Pro Gln 
1               5                   10                  15      


Arg Phe Phe Leu Thr Cys Val Ser Gly Glu Ala Gly Ala Gly Arg Gly 
            20                  25                  30          


Ser Asp Ala Trp Gly Pro Pro Leu Leu Leu Glu Lys Asp Asp Arg Ile 
        35                  40                  45              


Val Arg Thr Pro Pro Gly Pro Pro Leu Arg Leu Ala Arg Asn Gly Ser 
    50                  55                  60                  


His Gln Val Thr Leu Arg Gly Phe Ser Lys Pro Ser Asp Leu Val Gly 
65                  70                  75                  80  


Val Phe Ser Cys Val Gly Gly Ala Gly Ala Arg Arg Thr Arg Val Ile 
                85                  90                  95      


Tyr Val His Asn Ser Pro Gly Ala His Leu Leu Pro Asp Lys Val Thr 
            100                 105                 110         


His Thr Val Asn Lys Gly Asp Thr Ala Val Leu Ser Ala Arg Val His 
        115                 120                 125             


Lys Glu Lys Gln Thr Asp Val Ile Trp Lys Ser Asn Gly Ser Tyr Phe 
    130                 135                 140                 


Tyr Thr Leu Asp Trp His Glu Ala Gln Asp Gly Arg Phe Leu Leu Gln 
145                 150                 155                 160 


Leu Pro Asn Val Gln Pro Pro Ser Ser Gly Ile Tyr Ser Ala Thr Tyr 
                165                 170                 175     


Leu Glu Ala Ser Pro Leu Gly Ser Ala Phe Phe Arg Leu Ile Val Arg 
            180                 185                 190         


Gly Cys Gly Ala Gly Arg Trp Gly Pro Gly Cys Thr Lys Glu Cys Pro 
        195                 200                 205             


Gly Cys Leu His Gly Gly Val Cys His Asp His Asp Gly Glu Cys Val 
    210                 215                 220                 


Cys Pro Pro Gly Phe Thr Gly Thr Arg Cys Glu Gln Ala Cys Arg Glu 
225                 230                 235                 240 


Gly Arg Phe Gly Gln Ser Cys Gln Glu Gln Cys Pro Gly Ile Ser Gly 
                245                 250                 255     


Cys Arg Gly Leu Thr Phe Cys Leu Pro Asp Pro Tyr Gly Cys Ser Cys 
            260                 265                 270         


Gly Ser Gly Trp Arg Gly Ser Gln Cys Gln Glu Ala Cys Ala Pro Gly 
        275                 280                 285             


His Phe Gly Ala Asp Cys Arg Leu Gln Cys Gln Cys Gln Asn Gly Gly 
    290                 295                 300                 


Thr Cys Asp Arg Phe Ser Gly Cys Val Cys Pro Ser Gly Trp His Gly 
305                 310                 315                 320 


Val His Cys Glu Lys Ser Asp Arg Ile Pro Gln Ile Leu Asn Met Ala 
                325                 330                 335     


Ser Glu Leu Glu Phe Asn Leu Glu Thr Met Pro Arg Ile Asn Cys Ala 
            340                 345                 350         


Ala Ala Gly Asn Pro Phe Pro Val Arg Gly Ser Ile Glu Leu Arg Lys 
        355                 360                 365             


Pro Asp Gly Thr Val Leu Leu Ser Thr Lys Ala Ile Val Glu Pro Glu 
    370                 375                 380                 


Lys Thr Thr Ala Glu Phe Glu Val Pro Arg Leu Val Leu Ala Asp Ser 
385                 390                 395                 400 


Gly Phe Trp Glu Cys Arg Val Ser Thr Ser Gly Gly Gln Asp Ser Arg 
                405                 410                 415     


Arg Phe Lys Val Asn Val Lys Val Pro Pro Val Pro Leu Ala Ala Pro 
            420                 425                 430         


Arg Leu Leu Thr Lys Gln Ser Arg Gln Leu Val Val Ser Pro Leu Val 
        435                 440                 445             


Ser Phe Ser Gly Asp Gly Pro Ile Ser Thr Val Arg Leu His Tyr Arg 
    450                 455                 460                 


Pro Gln Asp Ser Thr Met Asp Trp Ser Thr Ile Val Val Asp Pro Ser 
465                 470                 475                 480 


Glu Asn Val Thr Leu Met Asn Leu Arg Pro Lys Thr Gly Tyr Ser Val 
                485                 490                 495     


Arg Val Gln Leu Ser Arg Pro Gly Glu Gly Gly Glu Gly Ala Trp Gly 
            500                 505                 510         


Pro Pro Thr Leu Met Thr Thr Asp Cys Pro Glu Pro Leu Leu Gln Pro 
        515                 520                 525             


Trp Leu Glu Gly Trp His Val Glu Gly Thr Asp Arg Leu Arg Val Ser 
    530                 535                 540                 


Trp Ser Leu Pro Leu Val Pro Gly Pro Leu Val Gly Asp Gly Phe Leu 
545                 550                 555                 560 


Leu Arg Leu Trp Asp Gly Thr Arg Gly Gln Glu Arg Arg Glu Asn Val 
                565                 570                 575     


Ser Ser Pro Gln Ala Arg Thr Ala Leu Leu Thr Gly Leu Thr Pro Gly 
            580                 585                 590         


Thr His Tyr Gln Leu Asp Val Gln Leu Tyr His Cys Thr Leu Leu Gly 
        595                 600                 605             


Pro Ala Ser Pro Pro Ala His Val Leu Leu Pro Pro Ser Gly Pro Pro 
    610                 615                 620                 


Ala Pro Arg His Leu His Ala Gln Ala Leu Ser Asp Ser Glu Ile Gln 
625                 630                 635                 640 


Leu Thr Trp Lys His Pro Glu Ala Leu Pro Gly Pro Ile Ser Lys Tyr 
                645                 650                 655     


Val Val Glu Val Gln Val Ala Gly Gly Ala Gly Asp Pro Leu Trp Ile 
            660                 665                 670         


Asp Val Asp Arg Pro Glu Glu Thr Ser Thr Ile Ile Arg Gly Leu Asn 
        675                 680                 685             


Ala Ser Thr Arg Tyr Leu Phe Arg Met Arg Ala Ser Ile Gln Gly Leu 
    690                 695                 700                 


Gly Asp Trp Ser Asn Thr Val Glu Glu Ser Thr Leu Gly Asn Gly Leu 
705                 710                 715                 720 


Gln Ala Glu Gly Pro Val Gln Glu Ser Arg Ala Ala Glu Glu Gly Leu 
                725                 730                 735     


Asp Gln 
        


<210>  1259
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  1259

Met Met Thr Gly Thr Ile Glu Thr Thr Gly Asn Ile Ser Ala Glu Lys 
1               5                   10                  15      


Gly Gly Ser Ile Ile Leu Gln Cys His Leu Ser Ser Thr Thr Ala Gln 
            20                  25                  30          


Val Thr Gln Val Asn Trp Glu Gln Gln Asp Gln Leu Leu Ala Ile Cys 
        35                  40                  45              


Asn Ala Asp Leu Gly Trp His Ile Ser Pro Ser Phe Lys Asp Arg Val 
    50                  55                  60                  


Ala Pro Gly Pro Gly Leu Gly Leu Thr Leu Gln Ser Leu Thr Val Asn 
65                  70                  75                  80  


Asp Thr Gly Glu Tyr Phe Cys Ile Tyr His Thr Tyr Pro Asp Gly Thr 
                85                  90                  95      


Tyr Thr Gly Arg Ile Phe Leu Glu Val Leu Glu Ser Ser Val Ala Glu 
            100                 105                 110         


His Gly Ala Arg Phe Gln Ile Pro 
        115                 120 


<210>  1260
<211>  290
<212>  PRT
<213>  Homo Sapiens

<400>  1260

Glu Thr Val Val Thr Glu Val Leu Gly His Arg Val Thr Leu Pro Cys 
1               5                   10                  15      


Leu Tyr Ser Ser Trp Ser His Asn Ser Asn Ser Met Cys Trp Gly Lys 
            20                  25                  30          


Asp Gln Cys Pro Tyr Ser Gly Cys Lys Glu Ala Leu Ile Arg Thr Asp 
        35                  40                  45              


Gly Met Arg Val Thr Ser Arg Lys Ser Ala Lys Tyr Arg Leu Gln Gly 
    50                  55                  60                  


Thr Ile Pro Arg Gly Asp Val Ser Leu Thr Ile Leu Asn Pro Ser Glu 
65                  70                  75                  80  


Ser Asp Ser Gly Val Tyr Cys Cys Arg Ile Glu Val Pro Gly Trp Phe 
                85                  90                  95      


Asn Asp Val Lys Ile Asn Val Arg Leu Asn Leu Gln Arg Ala Ser Thr 
            100                 105                 110         


Thr Thr His Arg Thr Ala Thr Thr Thr Thr Arg Arg Thr Thr Thr Thr 
        115                 120                 125             


Ser Pro Thr Thr Thr Arg Gln Met Thr Thr Thr Pro Ala Ala Leu Pro 
    130                 135                 140                 


Thr Thr Val Val Thr Thr Pro Asp Leu Thr Thr Gly Thr Pro Leu Gln 
145                 150                 155                 160 


Met Thr Thr Ile Ala Val Phe Thr Thr Ala Asn Thr Cys Leu Ser Leu 
                165                 170                 175     


Thr Pro Ser Thr Leu Pro Glu Glu Ala Thr Gly Leu Leu Thr Pro Glu 
            180                 185                 190         


Pro Ser Lys Glu Gly Pro Ile Leu Thr Ala Glu Ser Glu Thr Val Leu 
        195                 200                 205             


Pro Ser Asp Ser Trp Ser Ser Ala Glu Ser Thr Ser Ala Asp Thr Val 
    210                 215                 220                 


Leu Leu Thr Ser Lys Glu Ser Lys Val Trp Asp Leu Pro Ser Thr Ser 
225                 230                 235                 240 


His Val Ser Met Trp Lys Thr Ser Asp Ser Val Ser Ser Pro Gln Pro 
                245                 250                 255     


Gly Ala Ser Asp Thr Ala Val Pro Glu Gln Asn Lys Thr Thr Lys Thr 
            260                 265                 270         


Gly Gln Met Asp Gly Ile Pro Met Ser Met Lys Asn Glu Met Pro Ile 
        275                 280                 285             


Ser Gln 
    290 


<210>  1261
<211>  866
<212>  PRT
<213>  Homo Sapiens

<400>  1261

Ala Ala Thr Ser Arg Thr Glu Arg Ile Trp Pro Gly Gly Val Ile Pro 
1               5                   10                  15      


Tyr Val Ile Gly Gly Asn Phe Thr Gly Ser Gln Arg Ala Met Phe Lys 
            20                  25                  30          


Gln Ala Met Arg His Trp Glu Lys His Thr Cys Val Thr Phe Ile Glu 
        35                  40                  45              


Arg Ser Asp Glu Glu Ser Tyr Ile Val Phe Thr Tyr Arg Pro Cys Gly 
    50                  55                  60                  


Cys Cys Ser Tyr Val Gly Arg Arg Gly Asn Gly Pro Gln Ala Ile Ser 
65                  70                  75                  80  


Ile Gly Lys Asn Cys Asp Lys Phe Gly Ile Val Val His Glu Leu Gly 
                85                  90                  95      


His Val Ile Gly Phe Trp His Glu His Thr Arg Pro Asp Arg Asp Asn 
            100                 105                 110         


His Val Thr Ile Ile Arg Glu Asn Ile Gln Pro Gly Gln Glu Tyr Asn 
        115                 120                 125             


Phe Leu Lys Met Glu Pro Gly Glu Val Asn Ser Leu Gly Glu Arg Tyr 
    130                 135                 140                 


Asp Phe Asp Ser Ile Met His Tyr Ala Arg Asn Thr Phe Ser Arg Gly 
145                 150                 155                 160 


Met Phe Leu Asp Thr Ile Leu Pro Ser Arg Asp Asp Asn Gly Ile Arg 
                165                 170                 175     


Pro Ala Ile Gly Gln Arg Thr Arg Leu Ser Lys Gly Asp Ile Ala Gln 
            180                 185                 190         


Ala Arg Lys Leu Tyr Arg Cys Pro Ala Cys Gly Glu Thr Leu Gln Glu 
        195                 200                 205             


Ser Asn Gly Asn Leu Ser Ser Pro Gly Phe Pro Asn Gly Tyr Pro Ser 
    210                 215                 220                 


Tyr Thr His Cys Ile Trp Arg Val Ser Val Thr Pro Gly Glu Lys Ile 
225                 230                 235                 240 


Val Leu Asn Phe Thr Thr Met Asp Leu Tyr Lys Ser Ser Leu Cys Trp 
                245                 250                 255     


Tyr Asp Tyr Ile Glu Val Arg Asp Gly Tyr Trp Arg Lys Ser Pro Leu 
            260                 265                 270         


Leu Gly Arg Phe Cys Gly Asp Lys Leu Pro Glu Val Leu Thr Ser Thr 
        275                 280                 285             


Asp Ser Arg Met Trp Ile Glu Phe Arg Ser Ser Ser Asn Trp Val Gly 
    290                 295                 300                 


Lys Gly Phe Ala Ala Val Tyr Glu Ala Ile Cys Gly Gly Glu Ile Arg 
305                 310                 315                 320 


Lys Asn Glu Gly Gln Ile Gln Ser Pro Asn Tyr Pro Asp Asp Tyr Arg 
                325                 330                 335     


Pro Met Lys Glu Cys Val Trp Lys Ile Thr Val Ser Glu Ser Tyr His 
            340                 345                 350         


Val Gly Leu Thr Phe Gln Ser Phe Glu Ile Glu Arg His Asp Asn Cys 
        355                 360                 365             


Ala Tyr Asp Tyr Leu Glu Val Arg Asp Gly Thr Ser Glu Asn Ser Pro 
    370                 375                 380                 


Leu Ile Gly Arg Phe Cys Gly Tyr Asp Lys Pro Glu Asp Ile Arg Ser 
385                 390                 395                 400 


Thr Ser Asn Thr Leu Trp Met Lys Phe Val Ser Asp Gly Thr Val Asn 
                405                 410                 415     


Lys Ala Gly Phe Ala Ala Asn Phe Phe Lys Glu Glu Asp Glu Cys Ala 
            420                 425                 430         


Lys Pro Asp Arg Gly Gly Cys Glu Gln Arg Cys Leu Asn Thr Leu Gly 
        435                 440                 445             


Ser Tyr Gln Cys Ala Cys Glu Pro Gly Tyr Glu Leu Gly Pro Asp Arg 
    450                 455                 460                 


Arg Ser Cys Glu Ala Ala Cys Gly Gly Leu Leu Thr Lys Leu Asn Gly 
465                 470                 475                 480 


Thr Ile Thr Thr Pro Gly Trp Pro Lys Glu Tyr Pro Pro Asn Lys Asn 
                485                 490                 495     


Cys Val Trp Gln Val Val Ala Pro Thr Gln Tyr Arg Ile Ser Val Lys 
            500                 505                 510         


Phe Glu Phe Phe Glu Leu Glu Gly Asn Glu Val Cys Lys Tyr Asp Tyr 
        515                 520                 525             


Val Glu Ile Trp Ser Gly Leu Ser Ser Glu Ser Lys Leu His Gly Lys 
    530                 535                 540                 


Phe Cys Gly Ala Glu Val Pro Glu Val Ile Thr Ser Gln Phe Asn Asn 
545                 550                 555                 560 


Met Arg Ile Glu Phe Lys Ser Asp Asn Thr Val Ser Lys Lys Gly Phe 
                565                 570                 575     


Lys Ala His Phe Phe Ser Asp Lys Asp Glu Cys Ser Lys Asp Asn Gly 
            580                 585                 590         


Gly Cys Gln His Glu Cys Val Asn Thr Met Gly Ser Tyr Met Cys Gln 
        595                 600                 605             


Cys Arg Asn Gly Phe Val Leu His Asp Asn Lys His Asp Cys Lys Glu 
    610                 615                 620                 


Ala Glu Cys Glu Gln Lys Ile His Ser Pro Ser Gly Leu Ile Thr Ser 
625                 630                 635                 640 


Pro Asn Trp Pro Asp Lys Tyr Pro Ser Arg Lys Glu Cys Thr Trp Glu 
                645                 650                 655     


Ile Ser Ala Thr Pro Gly His Arg Ile Lys Leu Ala Phe Ser Glu Phe 
            660                 665                 670         


Glu Ile Glu Gln His Gln Glu Cys Ala Tyr Asp His Leu Glu Val Phe 
        675                 680                 685             


Asp Gly Glu Thr Glu Lys Ser Pro Ile Leu Gly Arg Leu Cys Gly Asn 
    690                 695                 700                 


Lys Ile Pro Asp Pro Leu Val Ala Thr Gly Asn Lys Met Phe Val Arg 
705                 710                 715                 720 


Phe Val Ser Asp Ala Ser Val Gln Arg Lys Gly Phe Gln Ala Thr His 
                725                 730                 735     


Ser Thr Glu Cys Gly Gly Arg Leu Lys Ala Glu Ser Lys Pro Arg Asp 
            740                 745                 750         


Leu Tyr Ser His Ala Gln Phe Gly Asp Asn Asn Tyr Pro Gly Gln Val 
        755                 760                 765             


Asp Cys Glu Trp Leu Leu Val Ser Glu Arg Gly Ser Arg Leu Glu Leu 
    770                 775                 780                 


Ser Phe Gln Thr Phe Glu Val Glu Glu Glu Ala Asp Cys Gly Tyr Asp 
785                 790                 795                 800 


Tyr Val Glu Leu Phe Asp Gly Leu Asp Ser Thr Ala Val Gly Leu Gly 
                805                 810                 815     


Arg Phe Cys Gly Ser Gly Pro Pro Glu Glu Ile Tyr Ser Ile Gly Asp 
            820                 825                 830         


Ser Val Leu Ile His Phe His Thr Asp Asp Thr Ile Asn Lys Lys Gly 
        835                 840                 845             


Phe His Ile Arg Tyr Lys Ser Ile Arg Tyr Pro Asp Thr Thr His Thr 
    850                 855                 860                 


Lys Lys 
865     


<210>  1262
<211>  866
<212>  PRT
<213>  Homo Sapiens

<400>  1262

Ala Thr Thr Ser Arg Thr Glu Arg Ile Trp Pro Gly Gly Val Ile Pro 
1               5                   10                  15      


Tyr Val Ile Gly Gly Asn Phe Thr Gly Ser Gln Arg Ala Ile Phe Lys 
            20                  25                  30          


Gln Ala Met Arg His Trp Glu Lys His Thr Cys Val Thr Phe Ile Glu 
        35                  40                  45              


Arg Thr Asp Glu Glu Ser Phe Ile Val Phe Ser Tyr Arg Thr Cys Gly 
    50                  55                  60                  


Cys Cys Ser Tyr Val Gly Arg Arg Gly Gly Gly Pro Gln Ala Ile Ser 
65                  70                  75                  80  


Ile Gly Lys Asn Cys Asp Lys Phe Gly Ile Val Ala His Glu Leu Gly 
                85                  90                  95      


His Val Val Gly Phe Trp His Glu His Thr Arg Pro Asp Arg Asp Gln 
            100                 105                 110         


His Val Thr Ile Ile Arg Glu Asn Ile Gln Pro Gly Gln Glu Tyr Asn 
        115                 120                 125             


Phe Leu Lys Met Glu Ala Gly Glu Val Ser Ser Leu Gly Glu Thr Tyr 
    130                 135                 140                 


Asp Phe Asp Ser Ile Met His Tyr Ala Arg Asn Thr Phe Ser Arg Gly 
145                 150                 155                 160 


Val Phe Leu Asp Thr Ile Leu Pro Arg Gln Asp Asp Asn Gly Val Arg 
                165                 170                 175     


Pro Thr Ile Gly Gln Arg Val Arg Leu Ser Gln Gly Asp Ile Ala Gln 
            180                 185                 190         


Ala Arg Lys Leu Tyr Lys Cys Pro Ala Cys Gly Glu Thr Leu Gln Asp 
        195                 200                 205             


Thr Thr Gly Asn Phe Ser Ala Pro Gly Phe Pro Asn Gly Tyr Pro Ser 
    210                 215                 220                 


Tyr Ser His Cys Val Trp Arg Ile Ser Val Thr Pro Gly Glu Lys Ile 
225                 230                 235                 240 


Val Leu Asn Phe Thr Ser Met Asp Leu Phe Lys Ser Arg Leu Cys Trp 
                245                 250                 255     


Tyr Asp Tyr Val Glu Val Arg Asp Gly Tyr Trp Arg Lys Ala Pro Leu 
            260                 265                 270         


Leu Gly Arg Phe Cys Gly Asp Lys Ile Pro Glu Pro Leu Val Ser Thr 
        275                 280                 285             


Asp Ser Arg Leu Trp Val Glu Phe Arg Ser Ser Ser Asn Ile Leu Gly 
    290                 295                 300                 


Lys Gly Phe Phe Ala Ala Tyr Glu Ala Thr Cys Gly Gly Asp Met Asn 
305                 310                 315                 320 


Lys Asp Ala Gly Gln Ile Gln Ser Pro Asn Tyr Pro Asp Asp Tyr Arg 
                325                 330                 335     


Pro Ser Lys Glu Cys Val Trp Arg Ile Thr Val Ser Glu Gly Phe His 
            340                 345                 350         


Val Gly Leu Thr Phe Gln Ala Phe Glu Ile Glu Arg His Asp Ser Cys 
        355                 360                 365             


Ala Tyr Asp Tyr Leu Glu Val Arg Asp Gly Pro Thr Glu Glu Ser Ala 
    370                 375                 380                 


Leu Ile Gly His Phe Cys Gly Tyr Glu Lys Pro Glu Asp Val Lys Ser 
385                 390                 395                 400 


Ser Ser Asn Arg Leu Trp Met Lys Phe Val Ser Asp Gly Ser Ile Asn 
                405                 410                 415     


Lys Ala Gly Phe Ala Ala Asn Phe Phe Lys Glu Val Asp Glu Cys Ser 
            420                 425                 430         


Trp Pro Asp His Gly Gly Cys Glu His Arg Cys Val Asn Thr Leu Gly 
        435                 440                 445             


Ser Tyr Lys Cys Ala Cys Asp Pro Gly Tyr Glu Leu Ala Ala Asp Lys 
    450                 455                 460                 


Lys Met Cys Glu Val Ala Cys Gly Gly Phe Ile Thr Lys Leu Asn Gly 
465                 470                 475                 480 


Thr Ile Thr Ser Pro Gly Trp Pro Lys Glu Tyr Pro Thr Asn Lys Asn 
                485                 490                 495     


Cys Val Trp Gln Val Val Ala Pro Ala Gln Tyr Arg Ile Ser Leu Gln 
            500                 505                 510         


Phe Glu Val Phe Glu Leu Glu Gly Asn Asp Val Cys Lys Tyr Asp Phe 
        515                 520                 525             


Val Glu Val Arg Ser Gly Leu Ser Pro Asp Ala Lys Leu His Gly Arg 
    530                 535                 540                 


Phe Cys Gly Ser Glu Thr Pro Glu Val Ile Thr Ser Gln Ser Asn Asn 
545                 550                 555                 560 


Met Arg Val Glu Phe Lys Ser Asp Asn Thr Val Ser Lys Arg Gly Phe 
                565                 570                 575     


Arg Ala His Phe Phe Ser Asp Lys Asp Glu Cys Ala Lys Asp Asn Gly 
            580                 585                 590         


Gly Cys Gln His Glu Cys Val Asn Thr Phe Gly Ser Tyr Leu Cys Arg 
        595                 600                 605             


Cys Arg Asn Gly Tyr Trp Leu His Glu Asn Gly His Asp Cys Lys Glu 
    610                 615                 620                 


Ala Gly Cys Ala His Lys Ile Ser Ser Val Glu Gly Thr Leu Ala Ser 
625                 630                 635                 640 


Pro Asn Trp Pro Asp Lys Tyr Pro Ser Arg Arg Glu Cys Thr Trp Asn 
                645                 650                 655     


Ile Ser Ser Thr Ala Gly His Arg Val Lys Leu Thr Phe Asn Glu Phe 
            660                 665                 670         


Glu Ile Glu Gln His Gln Glu Cys Ala Tyr Asp His Leu Glu Met Tyr 
        675                 680                 685             


Asp Gly Pro Asp Ser Leu Ala Pro Ile Leu Gly Arg Phe Cys Gly Ser 
    690                 695                 700                 


Lys Lys Pro Asp Pro Thr Val Ala Ser Gly Ser Ser Met Phe Leu Arg 
705                 710                 715                 720 


Phe Tyr Ser Asp Ala Ser Val Gln Arg Lys Gly Phe Gln Ala Val His 
                725                 730                 735     


Ser Thr Glu Cys Gly Gly Arg Leu Lys Ala Glu Val Gln Thr Lys Glu 
            740                 745                 750         


Leu Tyr Ser His Ala Gln Phe Gly Asp Asn Asn Tyr Pro Ser Glu Ala 
        755                 760                 765             


Arg Cys Asp Trp Val Ile Val Ala Glu Asp Gly Tyr Gly Val Glu Leu 
    770                 775                 780                 


Thr Phe Arg Thr Phe Glu Val Glu Glu Glu Ala Asp Cys Gly Tyr Asp 
785                 790                 795                 800 


Tyr Met Glu Ala Tyr Asp Gly Tyr Asp Ser Ser Ala Pro Arg Leu Gly 
                805                 810                 815     


Arg Phe Cys Gly Ser Gly Pro Leu Glu Glu Ile Tyr Ser Ala Gly Asp 
            820                 825                 830         


Ser Leu Met Ile Arg Phe Arg Thr Asp Asp Thr Ile Asn Lys Lys Gly 
        835                 840                 845             


Phe His Ala Arg Tyr Thr Ser Thr Lys Phe Gln Asp Ala Leu His Met 
    850                 855                 860                 


Lys Lys 
865     


<210>  1263
<211>  556
<212>  PRT
<213>  Homo Sapiens

<400>  1263

Ser Glu Phe Leu Val Asp Arg Ser Lys Asn Gly Leu Ile His Val Pro 
1               5                   10                  15      


Lys Asp Leu Ser Gln Lys Thr Thr Ile Leu Asn Ile Ser Gln Asn Tyr 
            20                  25                  30          


Ile Ser Glu Leu Trp Thr Ser Asp Ile Leu Ser Leu Ser Lys Leu Arg 
        35                  40                  45              


Ile Leu Ile Ile Ser His Asn Arg Ile Gln Tyr Leu Asp Ile Ser Val 
    50                  55                  60                  


Phe Lys Phe Asn Gln Glu Leu Glu Tyr Leu Asp Leu Ser His Asn Lys 
65                  70                  75                  80  


Leu Val Lys Ile Ser Cys His Pro Thr Val Asn Leu Lys His Leu Asp 
                85                  90                  95      


Leu Ser Phe Asn Ala Phe Asp Ala Leu Pro Ile Cys Lys Glu Phe Gly 
            100                 105                 110         


Asn Met Ser Gln Leu Lys Phe Leu Gly Leu Ser Thr Thr His Leu Glu 
        115                 120                 125             


Lys Ser Ser Val Leu Pro Ile Ala His Leu Asn Ile Ser Lys Val Leu 
    130                 135                 140                 


Leu Val Leu Gly Glu Thr Tyr Gly Glu Lys Glu Asp Pro Glu Gly Leu 
145                 150                 155                 160 


Gln Asp Phe Asn Thr Glu Ser Leu His Ile Val Phe Pro Thr Asn Lys 
                165                 170                 175     


Glu Phe His Phe Ile Leu Asp Val Ser Val Lys Thr Val Ala Asn Leu 
            180                 185                 190         


Glu Leu Ser Asn Ile Lys Cys Val Leu Glu Asp Asn Lys Cys Ser Tyr 
        195                 200                 205             


Phe Leu Ser Ile Leu Ala Lys Leu Gln Thr Asn Pro Lys Leu Ser Asn 
    210                 215                 220                 


Leu Thr Leu Asn Asn Ile Glu Thr Thr Trp Asn Ser Phe Ile Arg Ile 
225                 230                 235                 240 


Leu Gln Leu Val Trp His Thr Thr Val Trp Tyr Phe Ser Ile Ser Asn 
                245                 250                 255     


Val Lys Leu Gln Gly Gln Leu Asp Phe Arg Asp Phe Asp Tyr Ser Gly 
            260                 265                 270         


Thr Ser Leu Lys Ala Leu Ser Ile His Gln Val Val Ser Asp Val Phe 
        275                 280                 285             


Gly Phe Pro Gln Ser Tyr Ile Tyr Glu Ile Phe Ser Asn Met Asn Ile 
    290                 295                 300                 


Lys Asn Phe Thr Val Ser Gly Thr Arg Met Val His Met Leu Cys Pro 
305                 310                 315                 320 


Ser Lys Ile Ser Pro Phe Leu His Leu Asp Phe Ser Asn Asn Leu Leu 
                325                 330                 335     


Thr Asp Thr Val Phe Glu Asn Cys Gly His Leu Thr Glu Leu Glu Thr 
            340                 345                 350         


Leu Ile Leu Gln Met Asn Gln Leu Lys Glu Leu Ser Lys Ile Ala Glu 
        355                 360                 365             


Met Thr Thr Gln Met Lys Ser Leu Gln Gln Leu Asp Ile Ser Gln Asn 
    370                 375                 380                 


Ser Val Ser Tyr Asp Glu Lys Lys Gly Asp Cys Ser Trp Thr Lys Ser 
385                 390                 395                 400 


Leu Leu Ser Leu Asn Met Ser Ser Asn Ile Leu Thr Asp Thr Ile Phe 
                405                 410                 415     


Arg Cys Leu Pro Pro Arg Ile Lys Val Leu Asp Leu His Ser Asn Lys 
            420                 425                 430         


Ile Lys Ser Ile Pro Lys Gln Val Val Lys Leu Glu Ala Leu Gln Glu 
        435                 440                 445             


Leu Asn Val Ala Phe Asn Ser Leu Thr Asp Leu Pro Gly Cys Gly Ser 
    450                 455                 460                 


Phe Ser Ser Leu Ser Val Leu Ile Ile Asp His Asn Ser Val Ser His 
465                 470                 475                 480 


Pro Ser Ala Asp Phe Phe Gln Ser Cys Gln Lys Met Arg Ser Ile Lys 
                485                 490                 495     


Ala Gly Asp Asn Pro Phe Gln Cys Thr Cys Glu Leu Gly Glu Phe Val 
            500                 505                 510         


Lys Asn Ile Asp Gln Val Ser Ser Glu Val Leu Glu Gly Trp Pro Asp 
        515                 520                 525             


Ser Tyr Lys Cys Asp Tyr Pro Glu Ser Tyr Arg Gly Thr Leu Leu Lys 
    530                 535                 540                 


Asp Phe His Met Ser Glu Leu Ser Cys Asn Ile Thr 
545                 550                 555     


<210>  1264
<211>  557
<212>  PRT
<213>  Homo Sapiens

<400>  1264

Asp Ala Pro Glu Leu Pro Glu Glu Arg Glu Leu Met Thr Asn Cys Ser 
1               5                   10                  15      


Asn Met Ser Leu Arg Lys Val Pro Ala Asp Leu Thr Pro Ala Thr Thr 
            20                  25                  30          


Thr Leu Asp Leu Ser Tyr Asn Leu Leu Phe Gln Leu Gln Ser Ser Asp 
        35                  40                  45              


Phe His Ser Val Ser Lys Leu Arg Val Leu Ile Leu Cys His Asn Arg 
    50                  55                  60                  


Ile Gln Gln Leu Asp Leu Lys Thr Phe Glu Phe Asn Lys Glu Leu Arg 
65                  70                  75                  80  


Tyr Leu Asp Leu Ser Asn Asn Arg Leu Lys Ser Val Thr Trp Tyr Leu 
                85                  90                  95      


Leu Ala Gly Leu Arg Tyr Leu Asp Leu Ser Phe Asn Asp Phe Asp Thr 
            100                 105                 110         


Met Pro Ile Cys Glu Glu Ala Gly Asn Met Ser His Leu Glu Ile Leu 
        115                 120                 125             


Gly Leu Ser Gly Ala Lys Ile Gln Lys Ser Asp Phe Gln Lys Ile Ala 
    130                 135                 140                 


His Leu His Leu Asn Thr Val Phe Leu Gly Phe Arg Thr Leu Pro His 
145                 150                 155                 160 


Tyr Glu Glu Gly Ser Leu Pro Ile Leu Asn Thr Thr Lys Leu His Ile 
                165                 170                 175     


Val Leu Pro Met Asp Thr Asn Phe Trp Val Leu Leu Arg Asp Gly Ile 
            180                 185                 190         


Lys Thr Ser Lys Ile Leu Glu Met Thr Asn Ile Asp Gly Lys Ser Gln 
        195                 200                 205             


Phe Val Ser Tyr Glu Met Gln Arg Asn Leu Ser Leu Glu Asn Ala Lys 
    210                 215                 220                 


Thr Ser Val Leu Leu Leu Asn Lys Val Asp Leu Leu Trp Asp Asp Leu 
225                 230                 235                 240 


Phe Leu Ile Leu Gln Phe Val Trp His Thr Ser Val Glu His Phe Gln 
                245                 250                 255     


Ile Arg Asn Val Thr Phe Gly Gly Lys Ala Tyr Leu Asp His Asn Ser 
            260                 265                 270         


Phe Asp Tyr Ser Asn Thr Val Met Arg Thr Ile Lys Leu Glu His Val 
        275                 280                 285             


His Phe Arg Val Phe Tyr Ile Gln Gln Asp Lys Ile Tyr Leu Leu Leu 
    290                 295                 300                 


Thr Lys Met Asp Ile Glu Asn Leu Thr Ile Ser Asn Ala Gln Met Pro 
305                 310                 315                 320 


His Met Leu Phe Pro Asn Tyr Pro Thr Lys Phe Gln Tyr Leu Asn Phe 
                325                 330                 335     


Ala Asn Asn Ile Leu Thr Asp Glu Leu Phe Lys Arg Thr Ile Gln Leu 
            340                 345                 350         


Pro His Leu Lys Thr Leu Ile Leu Asn Gly Asn Lys Leu Glu Thr Leu 
        355                 360                 365             


Ser Leu Val Ser Cys Phe Ala Asn Asn Thr Pro Leu Glu His Leu Asp 
    370                 375                 380                 


Leu Ser Gln Asn Leu Leu Gln His Lys Asn Asp Glu Asn Cys Ser Trp 
385                 390                 395                 400 


Pro Glu Thr Val Val Asn Met Asn Leu Ser Tyr Asn Lys Leu Ser Asp 
                405                 410                 415     


Ser Val Phe Arg Cys Leu Pro Lys Ser Ile Gln Ile Leu Asp Leu Asn 
            420                 425                 430         


Asn Asn Gln Ile Gln Thr Val Pro Lys Glu Thr Ile His Leu Met Ala 
        435                 440                 445             


Leu Arg Glu Leu Asn Ile Ala Phe Asn Phe Leu Thr Asp Leu Pro Gly 
    450                 455                 460                 


Cys Ser His Phe Ser Arg Leu Ser Val Leu Asn Ile Glu Met Asn Phe 
465                 470                 475                 480 


Ile Leu Ser Pro Ser Leu Asp Phe Val Gln Ser Cys Gln Glu Val Lys 
                485                 490                 495     


Thr Leu Asn Ala Gly Arg Asn Pro Phe Arg Cys Thr Cys Glu Leu Lys 
            500                 505                 510         


Asn Phe Ile Gln Leu Glu Thr Tyr Ser Glu Val Met Met Val Gly Trp 
        515                 520                 525             


Ser Asp Ser Tyr Thr Cys Glu Tyr Pro Leu Asn Leu Arg Gly Thr Arg 
    530                 535                 540                 


Leu Lys Asp Val His Leu His Glu Leu Ser Cys Asn Thr 
545                 550                 555         


<210>  1265
<211>  568
<212>  PRT
<213>  Homo Sapiens

<400>  1265

Glu Ser Ser Asn Gln Ala Ser Leu Ser Cys Asp Arg Asn Gly Ile Cys 
1               5                   10                  15      


Lys Gly Ser Ser Gly Ser Leu Asn Ser Ile Pro Ser Gly Leu Thr Glu 
            20                  25                  30          


Ala Val Lys Ser Leu Asp Leu Ser Asn Asn Arg Ile Thr Tyr Ile Ser 
        35                  40                  45              


Asn Ser Asp Leu Gln Arg Cys Val Asn Leu Gln Ala Leu Val Leu Thr 
    50                  55                  60                  


Ser Asn Gly Ile Asn Thr Ile Glu Glu Asp Ser Phe Ser Ser Leu Gly 
65                  70                  75                  80  


Ser Leu Glu His Leu Asp Leu Ser Tyr Asn Tyr Leu Ser Asn Leu Ser 
                85                  90                  95      


Ser Ser Trp Phe Lys Pro Leu Ser Ser Leu Thr Phe Leu Asn Leu Leu 
            100                 105                 110         


Gly Asn Pro Tyr Lys Thr Leu Gly Glu Thr Ser Leu Phe Ser His Leu 
        115                 120                 125             


Thr Lys Leu Gln Ile Leu Arg Val Gly Asn Met Asp Thr Phe Thr Lys 
    130                 135                 140                 


Ile Gln Arg Lys Asp Phe Ala Gly Leu Thr Phe Leu Glu Glu Leu Glu 
145                 150                 155                 160 


Ile Asp Ala Ser Asp Leu Gln Ser Tyr Glu Pro Lys Ser Leu Lys Ser 
                165                 170                 175     


Ile Gln Asn Val Ser His Leu Ile Leu His Met Lys Gln His Ile Leu 
            180                 185                 190         


Leu Leu Glu Ile Phe Val Asp Val Thr Ser Ser Val Glu Cys Leu Glu 
        195                 200                 205             


Leu Arg Asp Thr Asp Leu Asp Thr Phe His Phe Ser Glu Leu Ser Thr 
    210                 215                 220                 


Gly Glu Thr Asn Ser Leu Ile Lys Lys Phe Thr Phe Arg Asn Val Lys 
225                 230                 235                 240 


Ile Thr Asp Glu Ser Leu Phe Gln Val Met Lys Leu Leu Asn Gln Ile 
                245                 250                 255     


Ser Gly Leu Leu Glu Leu Glu Phe Asp Asp Cys Thr Leu Asn Gly Val 
            260                 265                 270         


Gly Asn Phe Arg Ala Ser Asp Asn Asp Arg Val Ile Asp Pro Gly Lys 
        275                 280                 285             


Val Glu Thr Leu Thr Ile Arg Arg Leu His Ile Pro Arg Phe Tyr Leu 
    290                 295                 300                 


Phe Tyr Asp Leu Ser Thr Leu Tyr Ser Leu Thr Glu Arg Val Lys Arg 
305                 310                 315                 320 


Ile Thr Val Glu Asn Ser Lys Val Phe Leu Val Pro Cys Leu Leu Ser 
                325                 330                 335     


Gln His Leu Lys Ser Leu Glu Tyr Leu Asp Leu Ser Glu Asn Leu Met 
            340                 345                 350         


Val Glu Glu Tyr Leu Lys Asn Ser Ala Cys Glu Asp Ala Trp Pro Ser 
        355                 360                 365             


Leu Gln Thr Leu Ile Leu Arg Gln Asn His Leu Ala Ser Leu Glu Lys 
    370                 375                 380                 


Thr Gly Glu Thr Leu Leu Thr Leu Lys Asn Leu Thr Asn Ile Asp Ile 
385                 390                 395                 400 


Ser Lys Asn Ser Phe His Ser Met Pro Glu Thr Cys Gln Trp Pro Glu 
                405                 410                 415     


Lys Met Lys Tyr Leu Asn Leu Ser Ser Thr Arg Ile His Ser Val Thr 
            420                 425                 430         


Gly Cys Ile Pro Lys Thr Leu Glu Ile Leu Asp Val Ser Asn Asn Asn 
        435                 440                 445             


Leu Asn Leu Phe Ser Leu Asn Leu Pro Gln Leu Lys Glu Leu Tyr Ile 
    450                 455                 460                 


Ser Arg Asn Lys Leu Met Thr Leu Pro Asp Ala Ser Leu Leu Pro Met 
465                 470                 475                 480 


Leu Leu Val Leu Lys Ile Ser Arg Asn Ala Ile Thr Thr Phe Ser Lys 
                485                 490                 495     


Glu Gln Leu Asp Ser Phe His Thr Leu Lys Thr Leu Glu Ala Gly Gly 
            500                 505                 510         


Asn Asn Phe Ile Cys Ser Cys Glu Phe Leu Ser Phe Thr Gln Glu Gln 
        515                 520                 525             


Gln Ala Leu Ala Lys Val Leu Ile Asp Trp Pro Ala Asn Tyr Leu Cys 
    530                 535                 540                 


Asp Ser Pro Ser His Val Arg Gly Gln Gln Val Gln Asp Val Arg Leu 
545                 550                 555                 560 


Ser Val Ser Glu Cys His Arg Thr 
                565             


<210>  1266
<211>  681
<212>  PRT
<213>  Homo Sapiens

<400>  1266

Ser Thr Thr Lys Cys Thr Val Ser His Glu Val Ala Asp Cys Ser His 
1               5                   10                  15      


Leu Lys Leu Thr Gln Val Pro Asp Asp Leu Pro Thr Asn Ile Thr Val 
            20                  25                  30          


Leu Asn Leu Thr His Asn Gln Leu Arg Arg Leu Pro Ala Ala Asn Phe 
        35                  40                  45              


Thr Arg Tyr Ser Gln Leu Thr Ser Leu Asp Val Gly Phe Asn Thr Ile 
    50                  55                  60                  


Ser Lys Leu Glu Pro Glu Leu Cys Gln Lys Leu Pro Met Leu Lys Val 
65                  70                  75                  80  


Leu Asn Leu Gln His Asn Glu Leu Ser Gln Leu Ser Asp Lys Thr Phe 
                85                  90                  95      


Ala Phe Cys Thr Asn Leu Thr Glu Leu His Leu Met Ser Asn Ser Ile 
            100                 105                 110         


Gln Lys Ile Lys Asn Asn Pro Phe Val Lys Gln Lys Asn Leu Ile Thr 
        115                 120                 125             


Leu Asp Leu Ser His Asn Gly Leu Ser Ser Thr Lys Leu Gly Thr Gln 
    130                 135                 140                 


Val Gln Leu Glu Asn Leu Gln Glu Leu Leu Leu Ser Asn Asn Lys Ile 
145                 150                 155                 160 


Gln Ala Leu Lys Ser Glu Glu Leu Asp Ile Phe Ala Asn Ser Ser Leu 
                165                 170                 175     


Lys Lys Leu Glu Leu Ser Ser Asn Gln Ile Lys Glu Phe Ser Pro Gly 
            180                 185                 190         


Cys Phe His Ala Ile Gly Arg Leu Phe Gly Leu Phe Leu Asn Asn Val 
        195                 200                 205             


Gln Leu Gly Pro Ser Leu Thr Glu Lys Leu Cys Leu Glu Leu Ala Asn 
    210                 215                 220                 


Thr Ser Ile Arg Asn Leu Ser Leu Ser Asn Ser Gln Leu Ser Thr Thr 
225                 230                 235                 240 


Ser Asn Thr Thr Phe Leu Gly Leu Lys Trp Thr Asn Leu Thr Met Leu 
                245                 250                 255     


Asp Leu Ser Tyr Asn Asn Leu Asn Val Val Gly Asn Asp Ser Phe Ala 
            260                 265                 270         


Trp Leu Pro Gln Leu Glu Tyr Phe Phe Leu Glu Tyr Asn Asn Ile Gln 
        275                 280                 285             


His Leu Phe Ser His Ser Leu His Gly Leu Phe Asn Val Arg Tyr Leu 
    290                 295                 300                 


Asn Leu Lys Arg Ser Phe Thr Lys Gln Ser Ile Ser Leu Ala Ser Leu 
305                 310                 315                 320 


Pro Lys Ile Asp Asp Phe Ser Phe Gln Trp Leu Lys Cys Leu Glu His 
                325                 330                 335     


Leu Asn Met Glu Asp Asn Asp Ile Pro Gly Ile Lys Ser Asn Met Phe 
            340                 345                 350         


Thr Gly Leu Ile Asn Leu Lys Tyr Leu Ser Leu Ser Asn Ser Phe Thr 
        355                 360                 365             


Ser Leu Arg Thr Leu Thr Asn Glu Thr Phe Val Ser Leu Ala His Ser 
    370                 375                 380                 


Pro Leu His Ile Leu Asn Leu Thr Lys Asn Lys Ile Ser Lys Ile Glu 
385                 390                 395                 400 


Ser Asp Ala Phe Ser Trp Leu Gly His Leu Glu Val Leu Asp Leu Gly 
                405                 410                 415     


Leu Asn Glu Ile Gly Gln Glu Leu Thr Gly Gln Glu Trp Arg Gly Leu 
            420                 425                 430         


Glu Asn Ile Phe Glu Ile Tyr Leu Ser Tyr Asn Lys Tyr Leu Gln Leu 
        435                 440                 445             


Thr Arg Asn Ser Phe Ala Leu Val Pro Ser Leu Gln Arg Leu Met Leu 
    450                 455                 460                 


Arg Arg Val Ala Leu Lys Asn Val Asp Ser Ser Pro Ser Pro Phe Gln 
465                 470                 475                 480 


Pro Leu Arg Asn Leu Thr Ile Leu Asp Leu Ser Asn Asn Asn Ile Ala 
                485                 490                 495     


Asn Ile Asn Asp Asp Met Leu Glu Gly Leu Glu Lys Leu Glu Ile Leu 
            500                 505                 510         


Asp Leu Gln His Asn Asn Leu Ala Arg Leu Trp Lys His Ala Asn Pro 
        515                 520                 525             


Gly Gly Pro Ile Tyr Phe Leu Lys Gly Leu Ser His Leu His Ile Leu 
    530                 535                 540                 


Asn Leu Glu Ser Asn Gly Phe Asp Glu Ile Pro Val Glu Val Phe Lys 
545                 550                 555                 560 


Asp Leu Phe Glu Leu Lys Ile Ile Asp Leu Gly Leu Asn Asn Leu Asn 
                565                 570                 575     


Thr Leu Pro Ala Ser Val Phe Asn Asn Gln Val Ser Leu Lys Ser Leu 
            580                 585                 590         


Asn Leu Gln Lys Asn Leu Ile Thr Ser Val Glu Lys Lys Val Phe Gly 
        595                 600                 605             


Pro Ala Phe Arg Asn Leu Thr Glu Leu Asp Met Arg Phe Asn Pro Phe 
    610                 615                 620                 


Asp Cys Thr Cys Glu Ser Ile Ala Trp Phe Val Asn Trp Ile Asn Glu 
625                 630                 635                 640 


Thr His Thr Asn Ile Pro Glu Leu Ser Ser His Tyr Leu Cys Asn Thr 
                645                 650                 655     


Pro Pro His Tyr His Gly Phe Pro Val Arg Leu Phe Asp Thr Ser Ser 
            660                 665                 670         


Cys Lys Asp Ser Ala Pro Phe Glu Leu 
        675                 680     


<210>  1267
<211>  608
<212>  PRT
<213>  Homo Sapiens

<400>  1267

Glu Ser Trp Glu Pro Cys Val Glu Val Val Pro Asn Ile Thr Tyr Gln 
1               5                   10                  15      


Cys Met Glu Leu Asn Phe Tyr Lys Ile Pro Asp Asn Leu Pro Phe Ser 
            20                  25                  30          


Thr Lys Asn Leu Asp Leu Ser Phe Asn Pro Leu Arg His Leu Gly Ser 
        35                  40                  45              


Tyr Ser Phe Phe Ser Phe Pro Glu Leu Gln Val Leu Asp Leu Ser Arg 
    50                  55                  60                  


Cys Glu Ile Gln Thr Ile Glu Asp Gly Ala Tyr Gln Ser Leu Ser His 
65                  70                  75                  80  


Leu Ser Thr Leu Ile Leu Thr Gly Asn Pro Ile Gln Ser Leu Ala Leu 
                85                  90                  95      


Gly Ala Phe Ser Gly Leu Ser Ser Leu Gln Lys Leu Val Ala Val Glu 
            100                 105                 110         


Thr Asn Leu Ala Ser Leu Glu Asn Phe Pro Ile Gly His Leu Lys Thr 
        115                 120                 125             


Leu Lys Glu Leu Asn Val Ala His Asn Leu Ile Gln Ser Phe Lys Leu 
    130                 135                 140                 


Pro Glu Tyr Phe Ser Asn Leu Thr Asn Leu Glu His Leu Asp Leu Ser 
145                 150                 155                 160 


Ser Asn Lys Ile Gln Ser Ile Tyr Cys Thr Asp Leu Arg Val Leu His 
                165                 170                 175     


Gln Met Pro Leu Leu Asn Leu Ser Leu Asp Leu Ser Leu Asn Pro Met 
            180                 185                 190         


Asn Phe Ile Gln Pro Gly Ala Phe Lys Glu Ile Arg Leu His Lys Leu 
        195                 200                 205             


Thr Leu Arg Asn Asn Phe Asp Ser Leu Asn Val Met Lys Thr Cys Ile 
    210                 215                 220                 


Gln Gly Leu Ala Gly Leu Glu Val His Arg Leu Val Leu Gly Glu Phe 
225                 230                 235                 240 


Arg Asn Glu Gly Asn Leu Glu Lys Phe Asp Lys Ser Ala Leu Glu Gly 
                245                 250                 255     


Leu Cys Asn Leu Thr Ile Glu Glu Phe Arg Leu Ala Tyr Leu Asp Tyr 
            260                 265                 270         


Tyr Leu Asp Asp Ile Ile Asp Leu Phe Asn Cys Leu Thr Asn Val Ser 
        275                 280                 285             


Ser Phe Ser Leu Val Ser Val Thr Ile Glu Arg Val Lys Asp Phe Ser 
    290                 295                 300                 


Tyr Asn Phe Gly Trp Gln His Leu Glu Leu Val Asn Cys Lys Phe Gly 
305                 310                 315                 320 


Gln Phe Pro Thr Leu Lys Leu Lys Ser Leu Lys Arg Leu Thr Phe Thr 
                325                 330                 335     


Ser Asn Lys Gly Gly Asn Ala Phe Ser Glu Val Asp Leu Pro Ser Leu 
            340                 345                 350         


Glu Phe Leu Asp Leu Ser Arg Asn Gly Leu Ser Phe Lys Gly Cys Cys 
        355                 360                 365             


Ser Gln Ser Asp Phe Gly Thr Thr Ser Leu Lys Tyr Leu Asp Leu Ser 
    370                 375                 380                 


Phe Asn Gly Val Ile Thr Met Ser Ser Asn Phe Leu Gly Leu Glu Gln 
385                 390                 395                 400 


Leu Glu His Leu Asp Phe Gln His Ser Asn Leu Lys Gln Met Ser Glu 
                405                 410                 415     


Phe Ser Val Phe Leu Ser Leu Arg Asn Leu Ile Tyr Leu Asp Ile Ser 
            420                 425                 430         


His Thr His Thr Arg Val Ala Phe Asn Gly Ile Phe Asn Gly Leu Ser 
        435                 440                 445             


Ser Leu Glu Val Leu Lys Met Ala Gly Asn Ser Phe Gln Glu Asn Phe 
    450                 455                 460                 


Leu Pro Asp Ile Phe Thr Glu Leu Arg Asn Leu Thr Phe Leu Asp Leu 
465                 470                 475                 480 


Ser Gln Cys Gln Leu Glu Gln Leu Ser Pro Thr Ala Phe Asn Ser Leu 
                485                 490                 495     


Ser Ser Leu Gln Val Leu Asn Met Ser His Asn Asn Phe Phe Ser Leu 
            500                 505                 510         


Asp Thr Phe Pro Tyr Lys Cys Leu Asn Ser Leu Gln Val Leu Asp Tyr 
        515                 520                 525             


Ser Leu Asn His Ile Met Thr Ser Lys Lys Gln Glu Leu Gln His Phe 
    530                 535                 540                 


Pro Ser Ser Leu Ala Phe Leu Asn Leu Thr Gln Asn Asp Phe Ala Cys 
545                 550                 555                 560 


Thr Cys Glu His Gln Ser Phe Leu Gln Trp Ile Lys Asp Gln Arg Gln 
                565                 570                 575     


Leu Leu Val Glu Val Glu Arg Met Glu Cys Ala Thr Pro Ser Asp Lys 
            580                 585                 590         


Gln Gly Met Pro Val Leu Ser Leu Asn Ile Thr Cys Gln Met Asn Lys 
        595                 600                 605             


<210>  1268
<211>  619
<212>  PRT
<213>  Homo Sapiens

<400>  1268

Ile Pro Ser Cys Ser Phe Asp Gly Arg Ile Ala Phe Tyr Arg Phe Cys 
1               5                   10                  15      


Asn Leu Thr Gln Val Pro Gln Val Leu Asn Thr Thr Glu Arg Leu Leu 
            20                  25                  30          


Leu Ser Phe Asn Tyr Ile Arg Thr Val Thr Ala Ser Ser Phe Pro Phe 
        35                  40                  45              


Leu Glu Gln Leu Gln Leu Leu Glu Leu Gly Ser Gln Tyr Thr Pro Leu 
    50                  55                  60                  


Thr Ile Asp Lys Glu Ala Phe Arg Asn Leu Pro Asn Leu Arg Ile Leu 
65                  70                  75                  80  


Asp Leu Gly Ser Ser Lys Ile Tyr Phe Leu His Pro Asp Ala Phe Gln 
                85                  90                  95      


Gly Leu Phe His Leu Phe Glu Leu Arg Leu Tyr Phe Cys Gly Leu Ser 
            100                 105                 110         


Asp Ala Val Leu Lys Asp Gly Tyr Phe Arg Asn Leu Lys Ala Leu Thr 
        115                 120                 125             


Arg Leu Asp Leu Ser Lys Asn Gln Ile Arg Ser Leu Tyr Leu His Pro 
    130                 135                 140                 


Ser Phe Gly Lys Leu Asn Ser Leu Lys Ser Ile Asp Phe Ser Ser Asn 
145                 150                 155                 160 


Gln Ile Phe Leu Val Cys Glu His Glu Leu Glu Pro Leu Gln Gly Lys 
                165                 170                 175     


Thr Leu Ser Phe Phe Ser Leu Ala Ala Asn Ser Leu Tyr Ser Arg Val 
            180                 185                 190         


Ser Val Asp Trp Gly Lys Cys Met Asn Pro Phe Arg Asn Met Val Leu 
        195                 200                 205             


Glu Ile Leu Asp Val Ser Gly Asn Gly Trp Thr Val Asp Ile Thr Gly 
    210                 215                 220                 


Asn Phe Ser Asn Ala Ile Ser Lys Ser Gln Ala Phe Ser Leu Ile Leu 
225                 230                 235                 240 


Ala His His Ile Met Gly Ala Gly Phe Gly Phe His Asn Ile Lys Asp 
                245                 250                 255     


Pro Asp Gln Asn Thr Phe Ala Gly Leu Ala Arg Ser Ser Val Arg His 
            260                 265                 270         


Leu Asp Leu Ser His Gly Phe Val Phe Ser Leu Asn Ser Arg Val Phe 
        275                 280                 285             


Glu Thr Leu Lys Asp Leu Lys Val Leu Asn Leu Ala Tyr Asn Lys Ile 
    290                 295                 300                 


Asn Lys Ile Ala Asp Glu Ala Phe Tyr Gly Leu Asp Asn Leu Gln Val 
305                 310                 315                 320 


Leu Asn Leu Ser Tyr Asn Leu Leu Gly Glu Leu Tyr Ser Ser Asn Phe 
                325                 330                 335     


Tyr Gly Leu Pro Lys Val Ala Tyr Ile Asp Leu Gln Lys Asn His Ile 
            340                 345                 350         


Ala Ile Ile Gln Asp Gln Thr Phe Lys Phe Leu Glu Lys Leu Gln Thr 
        355                 360                 365             


Leu Asp Leu Arg Asp Asn Ala Leu Thr Thr Ile His Phe Ile Pro Ser 
    370                 375                 380                 


Ile Pro Asp Ile Phe Leu Ser Gly Asn Lys Leu Val Thr Leu Pro Lys 
385                 390                 395                 400 


Ile Asn Leu Thr Ala Asn Leu Ile His Leu Ser Glu Asn Arg Leu Glu 
                405                 410                 415     


Asn Leu Asp Ile Leu Tyr Phe Leu Leu Arg Val Pro His Leu Gln Ile 
            420                 425                 430         


Leu Ile Leu Asn Gln Asn Arg Phe Ser Ser Cys Ser Gly Asp Gln Thr 
        435                 440                 445             


Pro Ser Glu Asn Pro Ser Leu Glu Gln Leu Phe Leu Gly Glu Asn Met 
    450                 455                 460                 


Leu Gln Leu Ala Trp Glu Thr Glu Leu Cys Trp Asp Val Phe Glu Gly 
465                 470                 475                 480 


Leu Ser His Leu Gln Val Leu Tyr Leu Asn His Asn Tyr Leu Asn Ser 
                485                 490                 495     


Leu Pro Pro Gly Val Phe Ser His Leu Thr Ala Leu Arg Gly Leu Ser 
            500                 505                 510         


Leu Asn Ser Asn Arg Leu Thr Val Leu Ser His Asn Asp Leu Pro Ala 
        515                 520                 525             


Asn Leu Glu Ile Leu Asp Ile Ser Arg Asn Gln Leu Leu Ala Pro Asn 
    530                 535                 540                 


Pro Asp Val Phe Val Ser Leu Ser Val Leu Asp Ile Thr His Asn Lys 
545                 550                 555                 560 


Phe Ile Cys Glu Cys Glu Leu Ser Thr Phe Ile Asn Trp Leu Asn His 
                565                 570                 575     


Thr Asn Val Thr Ile Ala Gly Pro Pro Ala Asp Ile Tyr Cys Val Tyr 
            580                 585                 590         


Pro Asp Ser Phe Ser Gly Val Ser Leu Phe Ser Leu Ser Thr Glu Gly 
        595                 600                 605             


Cys Asp Glu Glu Glu Val Leu Lys Ser Leu Lys 
    610                 615                 


<210>  1269
<211>  449
<212>  PRT
<213>  Homo Sapiens

<400>  1269

Asn Glu Phe Ala Val Asp Lys Ser Lys Arg Gly Leu Ile His Val Pro 
1               5                   10                  15      


Lys Asp Leu Pro Leu Lys Thr Lys Val Leu Asp Met Ser Gln Asn Tyr 
            20                  25                  30          


Ile Ala Glu Leu Gln Val Ser Asp Met Ser Phe Leu Ser Glu Leu Thr 
        35                  40                  45              


Val Leu Arg Leu Ser His Asn Arg Ile Gln Leu Leu Asp Leu Ser Val 
    50                  55                  60                  


Phe Lys Phe Asn Gln Asp Leu Glu Tyr Leu Asp Leu Ser His Asn Gln 
65                  70                  75                  80  


Leu Gln Lys Ile Ser Cys His Pro Ile Val Ser Phe Arg His Leu Asp 
                85                  90                  95      


Leu Ser Phe Asn Asp Phe Lys Ala Leu Pro Ile Cys Lys Glu Phe Gly 
            100                 105                 110         


Asn Leu Ser Gln Leu Asn Phe Leu Gly Leu Ser Ala Met Lys Leu Gln 
        115                 120                 125             


Lys Leu Asp Leu Leu Pro Ile Ala His Leu His Leu Ser Tyr Ile Leu 
    130                 135                 140                 


Leu Asp Leu Arg Asn Tyr Tyr Ile Lys Glu Asn Glu Thr Glu Ser Leu 
145                 150                 155                 160 


Gln Ile Leu Asn Ala Lys Thr Leu His Leu Val Phe His Pro Thr Ser 
                165                 170                 175     


Leu Phe Ala Ile Gln Val Asn Ile Ser Val Asn Thr Leu Gly Cys Leu 
            180                 185                 190         


Gln Leu Thr Asn Ile Lys Leu Asn Asp Asp Asn Cys Gln Val Phe Ile 
        195                 200                 205             


Lys Phe Leu Ser Glu Leu Thr Arg Gly Pro Thr Leu Leu Asn Phe Thr 
    210                 215                 220                 


Leu Asn His Ile Glu Thr Thr Trp Lys Cys Leu Val Arg Val Phe Gln 
225                 230                 235                 240 


Phe Leu Trp Pro Lys Pro Val Glu Tyr Leu Asn Ile Tyr Asn Leu Thr 
                245                 250                 255     


Ile Ile Glu Ser Ile Arg Glu Glu Asp Phe Thr Tyr Ser Lys Thr Thr 
            260                 265                 270         


Leu Lys Ala Leu Thr Ile Glu His Ile Thr Asn Gln Val Phe Leu Phe 
        275                 280                 285             


Ser Gln Thr Ala Leu Tyr Thr Val Phe Ser Glu Met Asn Ile Met Met 
    290                 295                 300                 


Leu Thr Ile Ser Asp Thr Pro Phe Ile His Met Leu Cys Pro His Ala 
305                 310                 315                 320 


Pro Ser Thr Phe Lys Phe Leu Asn Phe Thr Gln Asn Val Phe Thr Asp 
                325                 330                 335     


Ser Ile Phe Glu Lys Cys Ser Thr Leu Val Lys Leu Glu Thr Leu Ile 
            340                 345                 350         


Phe Val Leu Ser Pro Asn Phe Val Gln Ser Glu Trp Cys His Tyr Glu 
        355                 360                 365             


Leu Tyr Phe Ala His His Asn Leu Phe His Glu Gly Ser Asn Asn Leu 
    370                 375                 380                 


Ile Leu Ile Leu Leu Glu Pro Ile Pro Gln Asn Ser Ile Pro Asn Lys 
385                 390                 395                 400 


Tyr His Lys Leu Lys Ala Leu Met Thr Gln Arg Thr Tyr Leu Gln Trp 
                405                 410                 415     


Pro Lys Glu Lys Ser Lys Arg Gly Leu Phe Trp Ala Asn Ile Arg Ala 
            420                 425                 430         


Ala Phe Asn Met Lys Leu Thr Leu Val Thr Glu Asn Asn Asp Val Lys 
        435                 440                 445             


Ser 
    


<210>  1270
<211>  813
<212>  PRT
<213>  Homo Sapiens

<400>  1270

Ala Arg Trp Phe Pro Lys Thr Leu Pro Cys Asp Val Thr Leu Asp Val 
1               5                   10                  15      


Pro Lys Asn His Val Ile Val Asp Cys Thr Asp Lys His Leu Thr Glu 
            20                  25                  30          


Ile Pro Gly Gly Ile Pro Thr Asn Thr Thr Asn Leu Thr Leu Thr Ile 
        35                  40                  45              


Asn His Ile Pro Asp Ile Ser Pro Ala Ser Phe His Arg Leu Asp His 
    50                  55                  60                  


Leu Val Glu Ile Asp Phe Arg Cys Asn Cys Val Pro Ile Pro Leu Gly 
65                  70                  75                  80  


Ser Lys Asn Asn Met Cys Ile Lys Arg Leu Gln Ile Lys Pro Arg Ser 
                85                  90                  95      


Phe Ser Gly Leu Thr Tyr Leu Lys Ser Leu Tyr Leu Asp Gly Asn Gln 
            100                 105                 110         


Leu Leu Glu Ile Pro Gln Gly Leu Pro Pro Ser Leu Gln Leu Leu Ser 
        115                 120                 125             


Leu Glu Ala Asn Asn Ile Phe Ser Ile Arg Lys Glu Asn Leu Thr Glu 
    130                 135                 140                 


Leu Ala Asn Ile Glu Ile Leu Tyr Leu Gly Gln Asn Cys Tyr Tyr Arg 
145                 150                 155                 160 


Asn Pro Cys Tyr Val Ser Tyr Ser Ile Glu Lys Asp Ala Phe Leu Asn 
                165                 170                 175     


Leu Thr Lys Leu Lys Val Leu Ser Leu Lys Asp Asn Asn Val Thr Ala 
            180                 185                 190         


Val Pro Thr Val Leu Pro Ser Thr Leu Thr Glu Leu Tyr Leu Tyr Asn 
        195                 200                 205             


Asn Met Ile Ala Lys Ile Gln Glu Asp Asp Phe Asn Asn Leu Asn Gln 
    210                 215                 220                 


Leu Gln Ile Leu Asp Leu Ser Gly Asn Cys Pro Arg Cys Tyr Asn Ala 
225                 230                 235                 240 


Pro Phe Pro Cys Ala Pro Cys Lys Asn Asn Ser Pro Leu Gln Ile Pro 
                245                 250                 255     


Val Asn Ala Phe Asp Ala Leu Thr Glu Leu Lys Val Leu Arg Leu His 
            260                 265                 270         


Ser Asn Ser Leu Gln His Val Pro Pro Arg Trp Phe Lys Asn Ile Asn 
        275                 280                 285             


Lys Leu Gln Glu Leu Asp Leu Ser Gln Asn Phe Leu Ala Lys Glu Ile 
    290                 295                 300                 


Gly Asp Ala Lys Phe Leu His Phe Leu Pro Ser Leu Ile Gln Leu Asp 
305                 310                 315                 320 


Leu Ser Phe Asn Phe Glu Leu Gln Val Tyr Arg Ala Ser Met Asn Leu 
                325                 330                 335     


Ser Gln Ala Phe Ser Ser Leu Lys Ser Leu Lys Ile Leu Arg Ile Arg 
            340                 345                 350         


Gly Tyr Val Phe Lys Glu Leu Lys Ser Phe Asn Leu Ser Pro Leu His 
        355                 360                 365             


Asn Leu Gln Asn Leu Glu Val Leu Asp Leu Gly Thr Asn Phe Ile Lys 
    370                 375                 380                 


Ile Ala Asn Leu Ser Met Phe Lys Gln Phe Lys Arg Leu Lys Val Ile 
385                 390                 395                 400 


Asp Leu Ser Val Asn Lys Ile Ser Pro Ser Gly Asp Ser Ser Glu Val 
                405                 410                 415     


Gly Phe Cys Ser Asn Ala Arg Thr Ser Val Glu Ser Tyr Glu Pro Gln 
            420                 425                 430         


Val Leu Glu Gln Leu His Tyr Phe Arg Tyr Asp Lys Tyr Ala Arg Ser 
        435                 440                 445             


Cys Arg Phe Lys Asn Lys Glu Ala Ser Phe Met Ser Val Asn Glu Ser 
    450                 455                 460                 


Cys Tyr Lys Tyr Gly Gln Thr Leu Asp Leu Ser Lys Asn Ser Ile Phe 
465                 470                 475                 480 


Phe Val Lys Ser Ser Asp Phe Gln His Leu Ser Phe Leu Lys Cys Leu 
                485                 490                 495     


Asn Leu Ser Gly Asn Leu Ile Ser Gln Thr Leu Asn Gly Ser Glu Phe 
            500                 505                 510         


Gln Pro Leu Ala Glu Leu Arg Tyr Leu Asp Phe Ser Asn Asn Arg Leu 
        515                 520                 525             


Asp Leu Leu His Ser Thr Ala Phe Glu Glu Leu His Lys Leu Glu Val 
    530                 535                 540                 


Leu Asp Ile Ser Ser Asn Ser His Tyr Phe Gln Ser Glu Gly Ile Thr 
545                 550                 555                 560 


His Met Leu Asn Phe Thr Lys Asn Leu Lys Val Leu Gln Lys Leu Met 
                565                 570                 575     


Met Asn Asp Asn Asp Ile Ser Ser Ser Thr Ser Arg Thr Met Glu Ser 
            580                 585                 590         


Glu Ser Leu Arg Thr Leu Glu Phe Arg Gly Asn His Leu Asp Val Leu 
        595                 600                 605             


Trp Arg Glu Gly Asp Asn Arg Tyr Leu Gln Leu Phe Lys Asn Leu Leu 
    610                 615                 620                 


Lys Leu Glu Glu Leu Asp Ile Ser Lys Asn Ser Leu Ser Phe Leu Pro 
625                 630                 635                 640 


Ser Gly Val Phe Asp Gly Met Pro Pro Asn Leu Lys Asn Leu Ser Leu 
                645                 650                 655     


Ala Lys Asn Gly Leu Lys Ser Phe Ser Trp Lys Lys Leu Gln Cys Leu 
            660                 665                 670         


Lys Asn Leu Glu Thr Leu Asp Leu Ser His Asn Gln Leu Thr Thr Val 
        675                 680                 685             


Pro Glu Arg Leu Ser Asn Cys Ser Arg Ser Leu Lys Asn Leu Ile Leu 
    690                 695                 700                 


Lys Asn Asn Gln Ile Arg Ser Leu Thr Lys Tyr Phe Leu Gln Asp Ala 
705                 710                 715                 720 


Phe Gln Leu Arg Tyr Leu Asp Leu Ser Ser Asn Lys Ile Gln Met Ile 
                725                 730                 735     


Gln Lys Thr Ser Phe Pro Glu Asn Val Leu Asn Asn Leu Lys Met Leu 
            740                 745                 750         


Leu Leu His His Asn Arg Phe Leu Cys Thr Cys Asp Ala Val Trp Phe 
        755                 760                 765             


Val Trp Trp Val Asn His Thr Glu Val Thr Ile Pro Tyr Leu Ala Thr 
    770                 775                 780                 


Asp Val Thr Cys Val Gly Pro Gly Ala His Lys Gly Gln Ser Val Ile 
785                 790                 795                 800 


Ser Leu Asp Leu Tyr Thr Cys Glu Leu Asp Leu Thr Asn 
                805                 810             


<210>  1271
<211>  801
<212>  PRT
<213>  Homo Sapiens

<400>  1271

Glu Glu Asn Phe Ser Arg Ser Tyr Pro Cys Asp Glu Lys Lys Gln Asn 
1               5                   10                  15      


Asp Ser Val Ile Ala Glu Cys Ser Asn Arg Arg Leu Gln Glu Val Pro 
            20                  25                  30          


Gln Thr Val Gly Lys Tyr Val Thr Glu Leu Asp Leu Ser Asp Asn Phe 
        35                  40                  45              


Ile Thr His Ile Thr Asn Glu Ser Phe Gln Gly Leu Gln Asn Leu Thr 
    50                  55                  60                  


Lys Ile Asn Leu Asn His Asn Pro Asn Val Gln His Gln Asn Gly Asn 
65                  70                  75                  80  


Pro Gly Ile Gln Ser Asn Gly Leu Asn Ile Thr Asp Gly Ala Phe Leu 
                85                  90                  95      


Asn Leu Lys Asn Leu Arg Glu Leu Leu Leu Glu Asp Asn Gln Leu Pro 
            100                 105                 110         


Gln Ile Pro Ser Gly Leu Pro Glu Ser Leu Thr Glu Leu Ser Leu Ile 
        115                 120                 125             


Gln Asn Asn Ile Tyr Asn Ile Thr Lys Glu Gly Ile Ser Arg Leu Ile 
    130                 135                 140                 


Asn Leu Lys Asn Leu Tyr Leu Ala Trp Asn Cys Tyr Phe Asn Lys Val 
145                 150                 155                 160 


Cys Glu Lys Thr Asn Ile Glu Asp Gly Val Phe Glu Thr Leu Thr Asn 
                165                 170                 175     


Leu Glu Leu Leu Ser Leu Ser Phe Asn Ser Leu Ser His Val Pro Pro 
            180                 185                 190         


Lys Leu Pro Ser Ser Leu Arg Lys Leu Phe Leu Ser Asn Thr Gln Ile 
        195                 200                 205             


Lys Tyr Ile Ser Glu Glu Asp Phe Lys Gly Leu Ile Asn Leu Thr Leu 
    210                 215                 220                 


Leu Asp Leu Ser Gly Asn Cys Pro Arg Cys Phe Asn Ala Pro Phe Pro 
225                 230                 235                 240 


Cys Val Pro Cys Asp Gly Gly Ala Ser Ile Asn Ile Asp Arg Phe Ala 
                245                 250                 255     


Phe Gln Asn Leu Thr Gln Leu Arg Tyr Leu Asn Leu Ser Ser Thr Ser 
            260                 265                 270         


Leu Arg Lys Ile Asn Ala Ala Trp Phe Lys Asn Met Pro His Leu Lys 
        275                 280                 285             


Val Leu Asp Leu Glu Phe Asn Tyr Leu Val Gly Glu Ile Ala Ser Gly 
    290                 295                 300                 


Ala Phe Leu Thr Met Leu Pro Arg Leu Glu Ile Leu Asp Leu Ser Phe 
305                 310                 315                 320 


Asn Tyr Ile Lys Gly Ser Tyr Pro Gln His Ile Asn Ile Ser Arg Asn 
                325                 330                 335     


Phe Ser Lys Leu Leu Ser Leu Arg Ala Leu His Leu Arg Gly Tyr Val 
            340                 345                 350         


Phe Gln Glu Leu Arg Glu Asp Asp Phe Gln Pro Leu Met Gln Leu Pro 
        355                 360                 365             


Asn Leu Ser Thr Ile Asn Leu Gly Ile Asn Phe Ile Lys Gln Ile Asp 
    370                 375                 380                 


Phe Lys Leu Phe Gln Asn Phe Ser Asn Leu Glu Ile Ile Tyr Leu Ser 
385                 390                 395                 400 


Glu Asn Arg Ile Ser Pro Leu Val Lys Asp Thr Arg Gln Ser Tyr Ala 
                405                 410                 415     


Asn Ser Ser Ser Phe Gln Arg His Ile Arg Lys Arg Arg Ser Thr Asp 
            420                 425                 430         


Phe Glu Phe Asp Pro His Ser Asn Phe Tyr His Phe Thr Arg Pro Leu 
        435                 440                 445             


Ile Lys Pro Gln Cys Ala Ala Tyr Gly Lys Ala Leu Asp Leu Ser Leu 
    450                 455                 460                 


Asn Ser Ile Phe Phe Ile Gly Pro Asn Gln Phe Glu Asn Leu Pro Asp 
465                 470                 475                 480 


Ile Ala Cys Leu Asn Leu Ser Ala Asn Ser Asn Ala Gln Val Leu Ser 
                485                 490                 495     


Gly Thr Glu Phe Ser Ala Ile Pro His Val Lys Tyr Leu Asp Leu Thr 
            500                 505                 510         


Asn Asn Arg Leu Asp Phe Asp Asn Ala Ser Ala Leu Thr Glu Leu Ser 
        515                 520                 525             


Asp Leu Glu Val Leu Asp Leu Ser Tyr Asn Ser His Tyr Phe Arg Ile 
    530                 535                 540                 


Ala Gly Val Thr His His Leu Glu Phe Ile Gln Asn Phe Thr Asn Leu 
545                 550                 555                 560 


Lys Val Leu Asn Leu Ser His Asn Asn Ile Tyr Thr Leu Thr Asp Lys 
                565                 570                 575     


Tyr Asn Leu Glu Ser Lys Ser Leu Val Glu Leu Val Phe Ser Gly Asn 
            580                 585                 590         


Arg Leu Asp Ile Leu Trp Asn Asp Asp Asp Asn Arg Tyr Ile Ser Ile 
        595                 600                 605             


Phe Lys Gly Leu Lys Asn Leu Thr Arg Leu Asp Leu Ser Leu Asn Arg 
    610                 615                 620                 


Leu Lys His Ile Pro Asn Glu Ala Phe Leu Asn Leu Pro Ala Ser Leu 
625                 630                 635                 640 


Thr Glu Leu His Ile Asn Asp Asn Met Leu Lys Phe Phe Asn Trp Thr 
                645                 650                 655     


Leu Leu Gln Gln Phe Pro Arg Leu Glu Leu Leu Asp Leu Arg Gly Asn 
            660                 665                 670         


Lys Leu Leu Phe Leu Thr Asp Ser Leu Ser Asp Phe Thr Ser Ser Leu 
        675                 680                 685             


Arg Thr Leu Leu Leu Ser His Asn Arg Ile Ser His Leu Pro Ser Gly 
    690                 695                 700                 


Phe Leu Ser Glu Val Ser Ser Leu Lys His Leu Asp Leu Ser Ser Asn 
705                 710                 715                 720 


Leu Leu Lys Thr Ile Asn Lys Ser Ala Leu Glu Thr Lys Thr Thr Thr 
                725                 730                 735     


Lys Leu Ser Met Leu Glu Leu His Gly Asn Pro Phe Glu Cys Thr Cys 
            740                 745                 750         


Asp Ile Gly Asp Phe Arg Arg Trp Met Asp Glu His Leu Asn Val Lys 
        755                 760                 765             


Ile Pro Arg Leu Val Asp Val Ile Cys Ala Ser Pro Gly Asp Gln Arg 
    770                 775                 780                 


Gly Lys Ser Ile Val Ser Leu Glu Leu Thr Thr Cys Val Ser Asp Val 
785                 790                 795                 800 


Thr 
    


<210>  1272
<211>  793
<212>  PRT
<213>  Homo Sapiens

<400>  1272

Leu Gly Thr Leu Pro Ala Phe Leu Pro Cys Glu Leu Gln Pro His Gly 
1               5                   10                  15      


Leu Val Asn Cys Asn Trp Leu Phe Leu Lys Ser Val Pro His Phe Ser 
            20                  25                  30          


Met Ala Ala Pro Arg Gly Asn Val Thr Ser Leu Ser Leu Ser Ser Asn 
        35                  40                  45              


Arg Ile His His Leu His Asp Ser Asp Phe Ala His Leu Pro Ser Leu 
    50                  55                  60                  


Arg His Leu Asn Leu Lys Trp Asn Cys Pro Pro Val Gly Leu Ser Pro 
65                  70                  75                  80  


Met His Phe Pro Cys His Met Thr Ile Glu Pro Ser Thr Phe Leu Ala 
                85                  90                  95      


Val Pro Thr Leu Glu Glu Leu Asn Leu Ser Tyr Asn Asn Ile Met Thr 
            100                 105                 110         


Val Pro Ala Leu Pro Lys Ser Leu Ile Ser Leu Ser Leu Ser His Thr 
        115                 120                 125             


Asn Ile Leu Met Leu Asp Ser Ala Ser Leu Ala Gly Leu His Ala Leu 
    130                 135                 140                 


Arg Phe Leu Phe Met Asp Gly Asn Cys Tyr Tyr Lys Asn Pro Cys Arg 
145                 150                 155                 160 


Gln Ala Leu Glu Val Ala Pro Gly Ala Leu Leu Gly Leu Gly Asn Leu 
                165                 170                 175     


Thr His Leu Ser Leu Lys Tyr Asn Asn Leu Thr Val Val Pro Arg Asn 
            180                 185                 190         


Leu Pro Ser Ser Leu Glu Tyr Leu Leu Leu Ser Tyr Asn Arg Ile Val 
        195                 200                 205             


Lys Leu Ala Pro Glu Asp Leu Ala Asn Leu Thr Ala Leu Arg Val Leu 
    210                 215                 220                 


Asp Val Gly Gly Asn Cys Arg Arg Cys Asp His Ala Pro Asn Pro Cys 
225                 230                 235                 240 


Met Glu Cys Pro Arg His Phe Pro Gln Leu His Pro Asp Thr Phe Ser 
                245                 250                 255     


His Leu Ser Arg Leu Glu Gly Leu Val Leu Lys Asp Ser Ser Leu Ser 
            260                 265                 270         


Trp Leu Asn Ala Ser Trp Phe Arg Gly Leu Gly Asn Leu Arg Val Leu 
        275                 280                 285             


Asp Leu Ser Glu Asn Phe Leu Tyr Lys Cys Ile Thr Lys Thr Lys Ala 
    290                 295                 300                 


Phe Gln Gly Leu Thr Gln Leu Arg Lys Leu Asn Leu Ser Phe Asn Tyr 
305                 310                 315                 320 


Gln Lys Arg Val Ser Phe Ala His Leu Ser Leu Ala Pro Ser Phe Gly 
                325                 330                 335     


Ser Leu Val Ala Leu Lys Glu Leu Asp Met His Gly Ile Phe Phe Arg 
            340                 345                 350         


Ser Leu Asp Glu Thr Thr Leu Arg Pro Leu Ala Arg Leu Pro Met Leu 
        355                 360                 365             


Gln Thr Leu Arg Leu Gln Met Asn Phe Ile Asn Gln Ala Gln Leu Gly 
    370                 375                 380                 


Ile Phe Arg Ala Phe Pro Gly Leu Arg Tyr Val Asp Leu Ser Asp Asn 
385                 390                 395                 400 


Arg Ile Ser Gly Ala Ser Glu Leu Thr Ala Thr Met Gly Glu Ala Asp 
                405                 410                 415     


Gly Gly Glu Lys Val Trp Leu Gln Pro Gly Asp Leu Ala Pro Ala Pro 
            420                 425                 430         


Val Asp Thr Pro Ser Ser Glu Asp Phe Arg Pro Asn Cys Ser Thr Leu 
        435                 440                 445             


Asn Phe Thr Leu Asp Leu Ser Arg Asn Asn Leu Val Thr Val Gln Pro 
    450                 455                 460                 


Glu Met Phe Ala Gln Leu Ser His Leu Gln Cys Leu Arg Leu Ser His 
465                 470                 475                 480 


Asn Cys Ile Ser Gln Ala Val Asn Gly Ser Gln Phe Leu Pro Leu Thr 
                485                 490                 495     


Gly Leu Gln Val Leu Asp Leu Ser His Asn Lys Leu Asp Leu Tyr His 
            500                 505                 510         


Glu His Ser Phe Thr Glu Leu Pro Arg Leu Glu Ala Leu Asp Leu Ser 
        515                 520                 525             


Tyr Asn Ser Gln Pro Phe Gly Met Gln Gly Val Gly His Asn Phe Ser 
    530                 535                 540                 


Phe Val Ala His Leu Arg Thr Leu Arg His Leu Ser Leu Ala His Asn 
545                 550                 555                 560 


Asn Ile His Ser Gln Val Ser Gln Gln Leu Cys Ser Thr Ser Leu Arg 
                565                 570                 575     


Ala Leu Asp Phe Ser Gly Asn Ala Leu Gly His Met Trp Ala Glu Gly 
            580                 585                 590         


Asp Leu Tyr Leu His Phe Phe Gln Gly Leu Ser Gly Leu Ile Trp Leu 
        595                 600                 605             


Asp Leu Ser Gln Asn Arg Leu His Thr Leu Leu Pro Gln Thr Leu Arg 
    610                 615                 620                 


Asn Leu Pro Lys Ser Leu Gln Val Leu Arg Leu Arg Asp Asn Tyr Leu 
625                 630                 635                 640 


Ala Phe Phe Lys Trp Trp Ser Leu His Phe Leu Pro Lys Leu Glu Val 
                645                 650                 655     


Leu Asp Leu Ala Gly Asn Gln Leu Lys Ala Leu Thr Asn Gly Ser Leu 
            660                 665                 670         


Pro Ala Gly Thr Arg Leu Arg Arg Leu Asp Val Ser Cys Asn Ser Ile 
        675                 680                 685             


Ser Phe Val Ala Pro Gly Phe Phe Ser Lys Ala Lys Glu Leu Arg Glu 
    690                 695                 700                 


Leu Asn Leu Ser Ala Asn Ala Leu Lys Thr Val Asp His Ser Trp Phe 
705                 710                 715                 720 


Gly Pro Leu Ala Ser Ala Leu Gln Ile Leu Asp Val Ser Ala Asn Pro 
                725                 730                 735     


Leu His Cys Ala Cys Gly Ala Ala Phe Met Asp Phe Leu Leu Glu Val 
            740                 745                 750         


Gln Ala Ala Val Pro Gly Leu Pro Ser Arg Val Lys Cys Gly Ser Pro 
        755                 760                 765             


Gly Gln Leu Gln Gly Leu Ser Ile Phe Ala Gln Asp Leu Arg Leu Cys 
    770                 775                 780                 


Leu Asp Glu Ala Leu Ser Trp Asp Cys 
785                 790             


<210>  1273
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  1273

Arg His Glu Ile Lys Asn Ser Phe Lys Asn Asn Tyr Glu Lys Ala Leu 
1               5                   10                  15      


Lys Gln Tyr Asn Ser Thr Gly Asp Tyr Arg Ser His Ala Val Asp Lys 
            20                  25                  30          


Ile Gln Asn Thr Leu His Cys Cys Gly Val Thr Asp Tyr Arg Asp Trp 
        35                  40                  45              


Thr Asp Thr Asn Tyr Tyr Ser Glu Lys Gly Phe Pro Lys Ser Cys Cys 
    50                  55                  60                  


Lys Leu Glu Asp Cys Thr Pro Gln Arg Asp Ala Asp Lys Val Asn Asn 
65                  70                  75                  80  


Glu Gly Cys Phe Ile Lys Val Met Thr Ile Ile Glu Ser Glu 
                85                  90                  


<210>  1274
<211>  291
<212>  PRT
<213>  Homo Sapiens

<400>  1274

Ser Asn Gln Pro Pro Gly Gly Gly Gly Gly Ser Gly Gly Asp Cys Pro 
1               5                   10                  15      


Gly Gly Lys Gly Lys Ser Ile Asn Cys Ser Glu Leu Asn Val Arg Glu 
            20                  25                  30          


Ser Asp Val Arg Val Cys Asp Glu Ser Ser Cys Lys Tyr Gly Gly Val 
        35                  40                  45              


Cys Lys Glu Asp Gly Asp Gly Leu Lys Cys Ala Cys Gln Phe Gln Cys 
    50                  55                  60                  


His Thr Asn Tyr Ile Pro Val Cys Gly Ser Asn Gly Asp Thr Tyr Gln 
65                  70                  75                  80  


Asn Glu Cys Phe Leu Arg Arg Ala Ala Cys Lys His Gln Lys Glu Ile 
                85                  90                  95      


Thr Val Ile Ala Arg Gly Pro Cys Tyr Ser Asp Asn Gly Ser Gly Ser 
            100                 105                 110         


Gly Glu Gly Glu Glu Glu Gly Ser Gly Ala Glu Val His Arg Lys His 
        115                 120                 125             


Ser Lys Cys Gly Pro Cys Lys Tyr Lys Ala Glu Cys Asp Glu Asp Ala 
    130                 135                 140                 


Glu Asn Val Gly Cys Val Cys Asn Ile Asp Cys Ser Gly Tyr Ser Phe 
145                 150                 155                 160 


Asn Pro Val Cys Ala Ser Asp Gly Ser Ser Tyr Asn Asn Pro Cys Phe 
                165                 170                 175     


Val Arg Glu Ala Ser Cys Ile Lys Gln Glu Gln Ile Asp Ile Arg His 
            180                 185                 190         


Leu Gly His Cys Thr Asp Thr Asp Asp Thr Ser Leu Leu Gly Lys Lys 
        195                 200                 205             


Asp Asp Gly Leu Gln Tyr Arg Pro Asp Val Lys Asp Ala Ser Asp Gln 
    210                 215                 220                 


Arg Glu Asp Val Tyr Ile Gly Asn His Met Pro Cys Pro Glu Asn Leu 
225                 230                 235                 240 


Asn Gly Tyr Cys Ile His Gly Lys Cys Glu Phe Ile Tyr Ser Thr Gln 
                245                 250                 255     


Lys Ala Ser Cys Arg Cys Glu Ser Gly Tyr Thr Gly Gln His Cys Glu 
            260                 265                 270         


Lys Thr Asp Phe Ser Ile Leu Tyr Val Val Pro Ser Arg Gln Lys Leu 
        275                 280                 285             


Thr His Val 
    290     


<210>  1275
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  1275

Phe Pro Thr Ser Leu Ser Asp Cys Gln Thr Pro Thr Gly Trp Asn Cys 
1               5                   10                  15      


Ser Gly Tyr Asp Asp Arg Glu Asn Asp Leu Phe Leu Cys Asp Thr Asn 
            20                  25                  30          


Thr Cys Lys Phe Asp Gly Glu Cys Leu Arg Ile Gly Asp Thr Val Thr 
        35                  40                  45              


Cys Val Cys Gln Phe Lys Cys Asn Asn Asp Tyr Val Pro Val Cys Gly 
    50                  55                  60                  


Ser Asn Gly Glu Ser Tyr Gln Asn Glu Cys Tyr Leu Arg Gln Ala Ala 
65                  70                  75                  80  


Cys Lys Gln Gln Ser Glu Ile Leu Val Val Ser Glu Gly Ser Cys Ala 
                85                  90                  95      


Thr Asp Ala Gly Ser Gly Ser Gly Asp Gly Val His Glu Gly Ser Gly 
            100                 105                 110         


Glu Thr Ser Gln Lys Glu Thr Ser Thr Cys Asp Ile Cys Gln Phe Gly 
        115                 120                 125             


Ala Glu Cys Asp Glu Asp Ala Glu Asp Val Trp Cys Val Cys Asn Ile 
    130                 135                 140                 


Asp Cys Ser Gln Thr Asn Phe Asn Pro Leu Cys Ala Ser Asp Gly Lys 
145                 150                 155                 160 


Ser Tyr Asp Asn Ala Cys Gln Ile Lys Glu Ala Ser Cys Gln Lys Gln 
                165                 170                 175     


Glu Lys Ile Glu Val Met Ser Leu Gly Arg Cys Gln Asp Asn Thr Thr 
            180                 185                 190         


Thr Thr Thr Lys Ser Glu Asp Gly His Tyr Ala Arg Thr Asp Tyr Ala 
        195                 200                 205             


Glu Asn Ala Asn Lys Leu Glu Glu Ser Ala Arg Glu His His Ile Pro 
    210                 215                 220                 


Cys Pro Glu His Tyr Asn Gly Phe Cys Met His Gly Lys Cys Glu His 
225                 230                 235                 240 


Ser Ile Asn Met Gln Glu Pro Ser Cys Arg Cys Asp Ala Gly Tyr Thr 
                245                 250                 255     


Gly Gln His Cys Glu Lys Lys Asp Tyr Ser Val Leu Tyr Val Val Pro 
            260                 265                 270         


Gly Pro Val Arg Phe Gln Tyr Val 
        275                 280 


<210>  1276
<211>  315
<212>  PRT
<213>  Homo Sapiens

<400>  1276

Gly Val Ala Ala Gly Leu Tyr Glu Leu Asn Leu Thr Thr Asp Ser Pro 
1               5                   10                  15      


Ala Thr Thr Gly Ala Val Val Thr Ile Ser Ala Ser Leu Val Ala Lys 
            20                  25                  30          


Asp Asn Gly Ser Leu Ala Leu Pro Ala Asp Ala His Leu Tyr Arg Phe 
        35                  40                  45              


His Trp Ile His Thr Pro Leu Val Leu Thr Gly Lys Met Glu Lys Gly 
    50                  55                  60                  


Leu Ser Ser Thr Ile Arg Val Val Gly His Val Pro Gly Glu Phe Pro 
65                  70                  75                  80  


Val Ser Val Trp Val Thr Ala Ala Asp Cys Trp Met Cys Gln Pro Val 
                85                  90                  95      


Ala Arg Gly Phe Val Val Leu Pro Ile Thr Glu Phe Leu Val Gly Asp 
            100                 105                 110         


Leu Val Val Thr Gln Asn Thr Ser Leu Pro Trp Pro Ser Ser Tyr Leu 
        115                 120                 125             


Thr Lys Thr Val Leu Lys Val Ser Phe Leu Leu His Asp Pro Ser Asn 
    130                 135                 140                 


Phe Leu Lys Thr Ala Leu Phe Leu Tyr Ser Trp Asp Phe Gly Asp Gly 
145                 150                 155                 160 


Thr Gln Met Val Thr Glu Asp Ser Val Val Tyr Tyr Asn Tyr Ser Ile 
                165                 170                 175     


Ile Gly Thr Phe Thr Val Lys Leu Lys Val Val Ala Glu Trp Glu Glu 
            180                 185                 190         


Val Glu Pro Asp Ala Thr Arg Ala Val Lys Gln Lys Thr Gly Asp Phe 
        195                 200                 205             


Ser Ala Ser Leu Lys Leu Gln Glu Thr Leu Arg Gly Ile Gln Val Leu 
    210                 215                 220                 


Gly Pro Thr Leu Ile Gln Thr Phe Gln Lys Met Thr Val Thr Leu Asn 
225                 230                 235                 240 


Phe Leu Gly Ser Pro Pro Leu Thr Val Cys Trp Arg Leu Lys Pro Glu 
                245                 250                 255     


Cys Leu Pro Leu Glu Glu Gly Glu Cys His Pro Val Ser Val Ala Ser 
            260                 265                 270         


Thr Ala Tyr Asn Leu Thr His Thr Phe Arg Asp Pro Gly Asp Tyr Cys 
        275                 280                 285             


Phe Ser Ile Arg Ala Glu Asn Ile Ile Ser Lys Thr His Gln Tyr His 
    290                 295                 300                 


Lys Ile Gln Val Trp Pro Ser Arg Ile Gln Pro 
305                 310                 315 


<210>  1277
<211>  141
<212>  PRT
<213>  Homo Sapiens

<400>  1277

Ser Gln Tyr Cys Gly Arg Leu Glu Tyr Trp Asn Pro Asp Asn Lys Cys 
1               5                   10                  15      


Cys Ser Ser Cys Leu Gln Arg Phe Gly Pro Pro Pro Cys Pro Asp Tyr 
            20                  25                  30          


Glu Phe Arg Glu Asn Cys Gly Leu Asn Asp His Gly Asp Phe Val Thr 
        35                  40                  45              


Pro Pro Phe Arg Lys Cys Ser Ser Gly Gln Cys Asn Pro Asp Gly Ala 
    50                  55                  60                  


Glu Leu Cys Ser Pro Cys Gly Gly Gly Ala Val Thr Pro Thr Pro Ala 
65                  70                  75                  80  


Ala Gly Gly Gly Arg Thr Pro Trp Arg Cys Arg Glu Arg Pro Val Pro 
                85                  90                  95      


Ala Lys Gly His Cys Pro Leu Thr Pro Gly Asn Pro Gly Ala Pro Ser 
            100                 105                 110         


Ser Gln Glu Arg Ser Ser Pro Ala Ser Ser Ile Ala Trp Arg Thr Pro 
        115                 120                 125             


Glu Pro Val Pro Gln Gln Ala Trp Pro Asn Phe Leu Pro 
    130                 135                 140     


<210>  1278
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  1278

Glu Leu Glu Pro Gln Ile Asp Gly Gln Thr Trp Ala Glu Arg Ala Leu 
1               5                   10                  15      


Arg Glu Asn Glu Arg His Ala Phe Thr Cys Arg Val Ala Gly Gly Pro 
            20                  25                  30          


Gly Thr Pro Arg Leu Ala Trp Tyr Leu Asp Gly Gln Leu Gln Glu Ala 
        35                  40                  45              


Ser Thr Ser Arg Leu Leu Ser Val Gly Gly Glu Ala Phe Ser Gly Gly 
    50                  55                  60                  


Thr Ser Thr Phe Thr Val Thr Ala His Arg Ala Gln His Glu Leu Asn 
65                  70                  75                  80  


Cys Ser Leu Gln Asp Pro Arg Ser Gly Arg Ser Ala Asn Ala Ser Val 
                85                  90                  95      


Ile Leu Asn Val Gln Phe Lys Pro Glu Ile Ala Gln Val Gly Ala Lys 
            100                 105                 110         


Tyr Gln Glu Ala Gln Gly Pro Gly Leu Leu Val Val Leu Phe Ala Leu 
        115                 120                 125             


Val Arg Ala Asn Pro Pro Ala Asn Val Thr Trp Ile Asp Gln Asp Gly 
    130                 135                 140                 


Pro Val Thr Val Asn Thr Ser Asp Phe Leu Val Leu Asp Ala Gln Asn 
145                 150                 155                 160 


Tyr Pro Trp Leu Thr Asn His Thr Val Gln Leu Gln Leu Arg Ser Leu 
                165                 170                 175     


Ala His Asn Leu Ser Val Val Ala Thr Asn Asp Val Gly Val Thr Ser 
            180                 185                 190         


Ala Ser Leu Pro Ala Pro Gly Leu Leu Ala Thr Arg Val Glu 
        195                 200                 205     


<210>  1279
<211>  511
<212>  PRT
<213>  Homo Sapiens

<400>  1279

Gly Tyr Ser Gly Lys Ser Glu Val Gly Leu Val Ser Glu His Phe Ser 
1               5                   10                  15      


Gln Ala Pro Gln Arg Leu Ser Phe Tyr Ser Trp Tyr Gly Ser Ala Arg 
            20                  25                  30          


Leu Phe Arg Phe Arg Val Pro Pro Asp Ala Val Leu Leu Arg Trp Leu 
        35                  40                  45              


Leu Gln Val Ser Arg Glu Ser Gly Ala Ala Cys Thr Asp Ala Glu Ile 
    50                  55                  60                  


Thr Val His Phe Arg Ser Gly Ala Pro Pro Val Ile Asn Pro Leu Gly 
65                  70                  75                  80  


Thr Ser Phe Pro Asp Asp Thr Ala Val Gln Pro Ser Phe Gln Val Gly 
                85                  90                  95      


Val Pro Leu Ser Thr Ala Pro Arg Ser Asn Ala Ser Val Asn Val Ser 
            100                 105                 110         


His Pro Ala Pro Gly Asp Trp Phe Val Ala Ala His Leu Pro Pro Ser 
        115                 120                 125             


Ser Gln Lys Ile Glu Leu Lys Gly Leu Ala Pro Thr Cys Ala Tyr Val 
    130                 135                 140                 


Phe Gln Pro Glu Leu Leu Val Thr Arg Val Val Glu Ile Ser Ile Met 
145                 150                 155                 160 


Glu Pro Asp Val Pro Leu Pro Gln Thr Leu Leu Ser His Pro Ser Tyr 
                165                 170                 175     


Leu Lys Val Phe Val Pro Asp Tyr Thr Arg Glu Leu Leu Leu Glu Leu 
            180                 185                 190         


Arg Asp Cys Val Ser Asn Gly Ser Leu Gly Cys Pro Val Arg Leu Thr 
        195                 200                 205             


Val Gly Pro Val Thr Leu Pro Ser Asn Phe Gln Lys Val Leu Thr Cys 
    210                 215                 220                 


Thr Gly Ala Pro Trp Pro Cys Arg Leu Leu Leu Pro Ser Pro Pro Trp 
225                 230                 235                 240 


Asp Arg Trp Leu Gln Val Thr Ala Glu Ser Leu Val Gly Pro Leu Gly 
                245                 250                 255     


Thr Val Ala Phe Ser Ala Val Ala Ala Leu Thr Ala Cys Arg Pro Arg 
            260                 265                 270         


Ser Val Thr Val Gln Pro Leu Leu Gln Ser Ser Gln Asn Gln Ser Phe 
        275                 280                 285             


Asn Ala Ser Ser Gly Leu Leu Ser Pro Ser Pro Asp His Gln Asp Leu 
    290                 295                 300                 


Gly Arg Ser Gly Arg Val Asp Arg Ser Pro Phe Cys Leu Thr Asn Tyr 
305                 310                 315                 320 


Pro Val Thr Arg Glu Asp Met Asp Val Val Ser Val His Phe Gln Pro 
                325                 330                 335     


Leu Asp Arg Val Ser Val Arg Val Cys Ser Asp Thr Pro Ser Val Met 
            340                 345                 350         


Arg Leu Arg Leu Asn Thr Gly Met Asp Ser Gly Gly Ser Leu Thr Ile 
        355                 360                 365             


Ser Leu Arg Ala Asn Lys Thr Glu Met Arg Asn Glu Thr Val Val Val 
    370                 375                 380                 


Ala Cys Val Asn Ala Ala Ser Pro Phe Leu Gly Phe Asn Thr Ser Leu 
385                 390                 395                 400 


Asn Cys Thr Thr Ala Phe Phe Gln Gly Tyr Pro Leu Ser Leu Ser Ala 
                405                 410                 415     


Trp Ser Arg Arg Ala Asn Leu Ile Ile Pro Tyr Pro Glu Thr Asp Asn 
            420                 425                 430         


Trp Tyr Leu Ser Leu Gln Leu Met Cys Pro Glu Asn Ala Glu Asp Cys 
        435                 440                 445             


Glu Gln Ala Val Val His Val Glu Thr Thr Leu Tyr Leu Val Pro Cys 
    450                 455                 460                 


Leu Asn Asp Cys Gly Pro Tyr Gly Gln Cys Leu Leu Leu Arg Arg His 
465                 470                 475                 480 


Ser Tyr Leu Tyr Ala Ser Cys Ser Cys Lys Ala Gly Trp Arg Gly Trp 
                485                 490                 495     


Ser Cys Thr Asp Asn Ser Thr Ala Gln Thr Val Ala Gln Gln Arg 
            500                 505                 510     


<210>  1280
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  1280

Ile Pro Glu Lys Leu Gln Glu Ala Val Gly Lys Val Ile Ile Asn Ala 
1               5                   10                  15      


Thr Thr Cys Thr Val Thr Cys Gly Leu Gly Tyr Lys Glu Glu Thr Val 
            20                  25                  30          


Cys Glu Val Gly Pro Asp Gly Val Arg Arg Lys Cys Gln Thr Arg Arg 
        35                  40                  45              


Leu Glu Cys Leu Thr Asn Trp Ile Cys Gly Met Leu His Phe Thr Ile 
    50                  55                  60                  


Leu Ile Gly Lys Glu Phe Glu Leu Ser Cys Leu Ser Ser Asp Ile Leu 
65                  70                  75                  80  


Glu Phe Gly Gln Glu Ala Phe Arg Phe Thr Trp Arg Leu Ala Arg Gly 
                85                  90                  95      


Val Ile Ser Thr Asp Asp Glu Val Phe Lys Pro Phe Gln Ala Asn Ser 
            100                 105                 110         


His Phe Val Lys Phe Lys Tyr Ala Gln Glu Tyr Asp Ser Gly Thr Tyr 
        115                 120                 125             


Arg Cys Asp Val Gln Leu Val Lys Asn Leu Arg Leu Val Lys Arg Leu 
    130                 135                 140                 


Tyr Phe Gly Leu Arg Val Leu Pro Pro Asn Leu Val Asn Leu Asn Phe 
145                 150                 155                 160 


His Gln Ser Leu Thr Glu Asp Gln Lys Leu Ile Asp Glu Gly Leu Glu 
                165                 170                 175     


Val Asn Leu Asp Ser Tyr Ser Lys Pro His His Pro Lys Trp Lys Lys 
            180                 185                 190         


Lys Val Ala Ser 
        195     


<210>  1281
<211>  233
<212>  PRT
<213>  Homo Sapiens

<400>  1281

Met Asn Met Pro Gln Ser Leu Gly Asn Gln Pro Leu Pro Pro Glu Pro 
1               5                   10                  15      


Pro Ser Leu Gly Thr Pro Ala Glu Gly Pro Gly Thr Thr Ser Pro Pro 
            20                  25                  30          


Glu His Cys Trp Pro Val Arg Pro Thr Leu Arg Asn Glu Leu Asp Thr 
        35                  40                  45              


Phe Ser Val His Phe Tyr Ile Phe Phe Gly Pro Ser Val Ala Leu Pro 
    50                  55                  60                  


Pro Glu Arg Pro Ala Val Phe Ala Met Arg Leu Leu Pro Val Leu Asp 
65                  70                  75                  80  


Ser Gly Gly Val Leu Ser Leu Glu Leu Gln Leu Asn Ala Ser Ser Val 
                85                  90                  95      


Arg Gln Glu Asn Val Thr Val Phe Gly Cys Leu Thr His Glu Val Pro 
            100                 105                 110         


Leu Ser Leu Gly Asp Ala Ala Val Thr Cys Ser Lys Glu Ser Leu Ala 
        115                 120                 125             


Gly Phe Leu Leu Ser Val Ser Ala Thr Thr Arg Val Ala Arg Leu Arg 
    130                 135                 140                 


Ile Pro Phe Pro Gln Thr Gly Thr Trp Phe Leu Ala Leu Arg Ser Leu 
145                 150                 155                 160 


Cys Gly Val Gly Pro Arg Phe Val Arg Cys Arg Asn Ala Thr Ala Glu 
                165                 170                 175     


Val Trp Met Arg Thr Phe Leu Ser Pro Cys Val Asp Asp Cys Gly Pro 
            180                 185                 190         


Tyr Gly Gln Cys Lys Leu Leu Arg Thr His Asn Tyr Leu Tyr Ala Ala 
        195                 200                 205             


Cys Glu Cys Lys Ala Gly Trp Arg Gly Trp Gly Cys Thr Asp Ser Ala 
    210                 215                 220                 


Asp Ala Leu Thr Tyr Gly Phe Gln Leu 
225                 230             


<210>  1282
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  1282

Val Leu Thr Val Asn Gly Lys Thr Glu Asn Tyr Ile Leu Asp Thr Thr 
1               5                   10                  15      


Pro Gly Ser Gln Ala Ser Leu Ile Cys Ala Val Gln Asn His Thr Arg 
            20                  25                  30          


Glu Glu Glu Leu Leu Trp Tyr Arg Glu Glu Gly Arg Val Asp Leu Lys 
        35                  40                  45              


Ser Gly Asn Lys Ile Asn Ser Ser Ser Val Cys Val Ser Ser Ile Ser 
    50                  55                  60                  


Glu Asn Asp Asn Gly Ile Ser Phe Thr Cys Arg Leu Gly Arg Asp Gln 
65                  70                  75                  80  


Ser Val Ser Val Ser Val Val Leu Asn Val Thr Phe Pro Pro Leu Leu 
                85                  90                  95      


Ser Gly Asn Asp Phe Gln Thr Val Glu Glu Gly Ser Asn Val Lys Leu 
            100                 105                 110         


Val Cys Asn Val Lys Ala Asn Pro Gln Ala Gln Met Met Trp Tyr Lys 
        115                 120                 125             


Asn Ser Ser Leu Leu Asp Leu Glu Lys Ser Arg His Gln Ile Gln Gln 
    130                 135                 140                 


Thr Ser Glu Ser Phe Gln Leu Ser Ile Thr Lys Val Glu Lys Pro Asp 
145                 150                 155                 160 


Asn Gly Thr Tyr Ser Cys Ile Ala Lys Ser Ser Leu Lys Thr Glu Ser 
                165                 170                 175     


Leu Asp Phe His Leu Ile Val Lys Asp Lys Thr Val Gly Val Pro 
            180                 185                 190     


<210>  1283
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  1283

Leu Ser Val Gln Gln Gly Pro Asn Leu Leu Gln Val Arg Gln Gly Ser 
1               5                   10                  15      


Gln Ala Thr Leu Val Cys Gln Val Asp Gln Ala Thr Ala Trp Glu Arg 
            20                  25                  30          


Leu Arg Val Lys Trp Thr Lys Asp Gly Ala Ile Leu Cys Gln Pro Tyr 
        35                  40                  45              


Ile Thr Asn Gly Ser Leu Ser Leu Gly Val Cys Gly Pro Gln Gly Arg 
    50                  55                  60                  


Leu Ser Trp Gln Ala Pro Ser His Leu Thr Leu Gln Leu Asp Pro Val 
65                  70                  75                  80  


Ser Leu Asn His Ser Gly Ala Tyr Val Cys Trp Ala Ala Val Glu Ile 
                85                  90                  95      


Pro Glu Leu Glu Glu Ala Glu Gly Asn Ile Thr Arg Leu Phe Val Asp 
            100                 105                 110         


Pro Asp Asp Pro Thr Gln Asn Arg Asn Arg Ile Ala Ser Phe Pro Gly 
        115                 120                 125             


<210>  1284
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  1284

Glu Pro Pro Thr Gln Lys Pro Lys Lys Ile Val Asn Ala Lys Lys Asp 
1               5                   10                  15      


Val Val Asn Thr Lys Met Phe Glu Glu Leu Lys Ser Arg Leu Asp Thr 
            20                  25                  30          


Leu Ala Gln Glu Val Ala Leu Leu Lys Glu Gln Gln Ala Leu Gln Thr 
        35                  40                  45              


Val Cys Leu Lys Gly Thr Lys Val His Met Lys Cys Phe Leu Ala Phe 
    50                  55                  60                  


Thr Gln Thr Lys Thr Phe His Glu Ala Ser Glu Asp Cys Ile Ser Arg 
65                  70                  75                  80  


Gly Gly Thr Leu Ser Thr Pro Gln Thr Gly Ser Glu Asn Asp Ala Leu 
                85                  90                  95      


Tyr Glu Tyr Leu Arg Gln Ser Val Gly Asn Glu Ala Glu Ile Trp Leu 
            100                 105                 110         


Gly Leu Asn Asp Met Ala Ala Glu Gly Thr Trp Val Asp Met Thr Gly 
        115                 120                 125             


Ala Arg Ile Ala Tyr Lys Asn Trp Glu Thr Glu Ile Thr Ala Gln Pro 
    130                 135                 140                 


Asp Gly Gly Lys Thr Glu Asn Cys Ala Val Leu Ser Gly Ala Ala Asn 
145                 150                 155                 160 


Gly Lys Trp Phe Asp Lys Arg Cys Arg Asp Gln Leu Pro Tyr Ile Cys 
                165                 170                 175     


Gln Phe Gly Ile Val 
            180     


<210>  1285
<211>  157
<212>  PRT
<213>  Homo Sapiens

<400>  1285

Val Arg Ser Ser Ser Arg Thr Pro Ser Asp Lys Pro Val Ala His Val 
1               5                   10                  15      


Val Ala Asn Pro Gln Ala Glu Gly Gln Leu Gln Trp Leu Asn Arg Arg 
            20                  25                  30          


Ala Asn Ala Leu Leu Ala Asn Gly Val Glu Leu Arg Asp Asn Gln Leu 
        35                  40                  45              


Val Val Pro Ser Glu Gly Leu Tyr Leu Ile Tyr Ser Gln Val Leu Phe 
    50                  55                  60                  


Lys Gly Gln Gly Cys Pro Ser Thr His Val Leu Leu Thr His Thr Ile 
65                  70                  75                  80  


Ser Arg Ile Ala Val Ser Tyr Gln Thr Lys Val Asn Leu Leu Ser Ala 
                85                  90                  95      


Ile Lys Ser Pro Cys Gln Arg Glu Thr Pro Glu Gly Ala Glu Ala Lys 
            100                 105                 110         


Pro Trp Tyr Glu Pro Ile Tyr Leu Gly Gly Val Phe Gln Leu Glu Lys 
        115                 120                 125             


Gly Asp Arg Leu Ser Ala Glu Ile Asn Arg Pro Asp Tyr Leu Asp Phe 
    130                 135                 140                 


Ala Glu Ser Gly Gln Val Tyr Phe Gly Ile Ile Ala Leu 
145                 150                 155         


<210>  1286
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  1286

Ala Ser Gly Thr Glu Ala Ala Ala Ala Thr Pro Ser Lys Val Trp Gly 
1               5                   10                  15      


Ser Ser Ala Gly Arg Ile Glu Pro Arg Gly Gly Gly Arg Gly Ala Leu 
            20                  25                  30          


Pro Thr Ser Met Gly Gln His Gly Pro Ser Ala Arg Ala Arg Ala Gly 
        35                  40                  45              


Arg Ala Pro Gly Pro Arg Pro Ala Arg Glu Ala Ser Pro Arg Leu Arg 
    50                  55                  60                  


Val His Lys Thr Phe Lys Phe Val Val Val Gly Val Leu Leu Gln Val 
65                  70                  75                  80  


Val Pro Ser Ser Ala Ala Thr Ile Lys Leu His Asp Gln Ser Ile Gly 
                85                  90                  95      


Thr Gln Gln Trp Glu His Ser Pro Leu Gly Glu Leu Cys Pro Pro Gly 
            100                 105                 110         


Ser His Arg Ser Glu His Pro Gly Ala Cys Asn Arg Cys Thr Glu Gly 
        115                 120                 125             


Val Gly Tyr Thr Asn Ala Ser Asn Asn Leu Phe Ala Cys Leu Pro Cys 
    130                 135                 140                 


Thr Ala Cys Lys Ser Asp Glu Glu Glu Arg Ser Pro Cys Thr Thr Thr 
145                 150                 155                 160 


Arg Asn Thr Ala Cys Gln Cys Lys Pro Gly Thr Phe Arg Asn Asp Asn 
                165                 170                 175     


Ser Ala Glu Met Cys Arg Lys Cys Ser Arg Gly Cys Pro Arg Gly Met 
            180                 185                 190         


Val Lys Val Lys Asp Cys Thr Pro Trp Ser Asp Ile Glu Cys Val His 
        195                 200                 205             


Lys Glu Ser Gly Asn Gly His Asn 
    210                 215     


<210>  1287
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  1287

Ile Thr Gln Gln Asp Leu Ala Pro Gln Gln Arg Ala Ala Pro Gln Gln 
1               5                   10                  15      


Lys Arg Ser Ser Pro Ser Glu Gly Leu Cys Pro Pro Gly His His Ile 
            20                  25                  30          


Ser Glu Asp Gly Arg Asp Cys Ile Ser Cys Lys Tyr Gly Gln Asp Tyr 
        35                  40                  45              


Ser Thr His Trp Asn Asp Leu Leu Phe Cys Leu Arg Cys Thr Arg Cys 
    50                  55                  60                  


Asp Ser Gly Glu Val Glu Leu Ser Pro Cys Thr Thr Thr Arg Asn Thr 
65                  70                  75                  80  


Val Cys Gln Cys Glu Glu Gly Thr Phe Arg Glu Glu Asp Ser Pro Glu 
                85                  90                  95      


Met Cys Arg Lys Cys Arg Thr Gly Cys Pro Arg Gly Met Val Lys Val 
            100                 105                 110         


Gly Asp Cys Thr Pro Trp Ser Asp Ile Glu Cys Val His Lys Glu Ser 
        115                 120                 125             


Gly Thr Lys His Ser Gly Glu Ala Pro Ala Val Glu Glu Thr Val Thr 
    130                 135                 140                 


Ser Ser Pro Gly Thr Pro Ala Ser Pro Cys Ser 
145                 150                 155 


<210>  1288
<211>  151
<212>  PRT
<213>  Homo Sapiens

<400>  1288

Ala Thr Thr Ala Arg Gln Glu Glu Val Pro Gln Gln Thr Val Ala Pro 
1               5                   10                  15      


Gln Gln Gln Arg His Ser Phe Lys Gly Glu Glu Cys Pro Ala Gly Ser 
            20                  25                  30          


His Arg Ser Glu His Thr Gly Ala Cys Asn Pro Cys Thr Glu Gly Val 
        35                  40                  45              


Asp Tyr Thr Asn Ala Ser Asn Asn Glu Pro Ser Cys Phe Pro Cys Thr 
    50                  55                  60                  


Val Cys Lys Ser Asp Gln Lys His Lys Ser Ser Cys Thr Met Thr Arg 
65                  70                  75                  80  


Asp Thr Val Cys Gln Cys Lys Glu Gly Thr Phe Arg Asn Glu Asn Ser 
                85                  90                  95      


Pro Glu Met Cys Arg Lys Cys Ser Arg Cys Pro Ser Gly Glu Val Gln 
            100                 105                 110         


Val Ser Asn Cys Thr Ser Trp Asp Asp Ile Gln Cys Val Glu Glu Phe 
        115                 120                 125             


Gly Ala Asn Ala Thr Val Glu Thr Pro Ala Ala Glu Glu Thr Met Asn 
    130                 135                 140                 


Thr Ser Pro Gly Thr Pro Ala 
145                 150     


<210>  1289
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  1289

Ala Thr Ile Pro Arg Gln Asp Glu Val Pro Gln Gln Thr Val Ala Pro 
1               5                   10                  15      


Gln Gln Gln Arg Arg Ser Leu Lys Glu Glu Glu Cys Pro Ala Gly Ser 
            20                  25                  30          


His Arg Ser Glu Tyr Thr Gly Ala Cys Asn Pro Cys Thr Glu Gly Val 
        35                  40                  45              


Asp Tyr Thr Ile Ala Ser Asn Asn Leu Pro Ser Cys Leu Leu Cys Thr 
    50                  55                  60                  


Val Cys Lys Ser Gly Gln Thr Asn Lys Ser Ser Cys Thr Thr Thr Arg 
65                  70                  75                  80  


Asp Thr Val Cys Gln Cys Glu Lys Gly Ser Phe Gln Asp Lys Asn Ser 
                85                  90                  95      


Pro Glu Met Cys Arg Thr Cys Arg Thr Gly Cys Pro Arg Gly Met Val 
            100                 105                 110         


Lys Val Ser Asn Cys Thr Pro Arg Ser Asp Ile Lys Cys Lys Asn Glu 
        115                 120                 125             


Ser Ala Ala Ser Ser Thr Gly Lys Thr Pro Ala Ala Glu Glu Thr Val 
    130                 135                 140                 


Thr Thr Ile Leu Gly Met Leu Ala Ser Pro Tyr His 
145                 150                 155     


<210>  1290
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  1290

Ile Ala Pro Pro Cys Thr Ser Glu Lys His Tyr Glu His Leu Gly Arg 
1               5                   10                  15      


Cys Cys Asn Lys Cys Glu Pro Gly Lys Tyr Met Ser Ser Lys Cys Thr 
            20                  25                  30          


Thr Thr Ser Asp Ser Val Cys Leu Pro Cys Gly Pro Asp Glu Tyr Leu 
        35                  40                  45              


Asp Ser Trp Asn Glu Glu Asp Lys Cys Leu Leu His Lys Val Cys Asp 
    50                  55                  60                  


Thr Gly Lys Ala Leu Val Ala Val Val Ala Gly Asn Ser Thr Thr Pro 
65                  70                  75                  80  


Arg Arg Cys Ala Cys Thr Ala Gly Tyr His Trp Ser Gln Asp Cys Glu 
                85                  90                  95      


Cys Cys Arg Arg Asn Thr Glu Cys Ala Pro Gly Leu Gly Ala Gln His 
            100                 105                 110         


Pro Leu Gln Leu Asn Lys Asp Thr Val Cys Lys Pro Cys Leu Ala Gly 
        115                 120                 125             


Tyr Phe Ser Asp Ala Phe Ser Ser Thr Asp Lys Cys Arg Pro Trp Thr 
    130                 135                 140                 


Asn Cys Thr Phe Leu Gly Lys Arg Val Glu His His Gly Thr Glu Lys 
145                 150                 155                 160 


Ser Asp Ala Val Cys Ser Ser Ser Leu Pro Ala Arg Lys Pro Pro Asn 
                165                 170                 175     


Glu Pro His Val Tyr Leu Pro 
            180             


<210>  1291
<211>  380
<212>  PRT
<213>  Homo Sapiens

<400>  1291

Glu Thr Phe Pro Pro Lys Tyr Leu His Tyr Asp Glu Glu Thr Ser His 
1               5                   10                  15      


Gln Leu Leu Cys Asp Lys Cys Pro Pro Gly Thr Tyr Leu Lys Gln His 
            20                  25                  30          


Cys Thr Ala Lys Trp Lys Thr Val Cys Ala Pro Cys Pro Asp His Tyr 
        35                  40                  45              


Tyr Thr Asp Ser Trp His Thr Ser Asp Glu Cys Leu Tyr Cys Ser Pro 
    50                  55                  60                  


Val Cys Lys Glu Leu Gln Tyr Val Lys Gln Glu Cys Asn Arg Thr His 
65                  70                  75                  80  


Asn Arg Val Cys Glu Cys Lys Glu Gly Arg Tyr Leu Glu Ile Glu Phe 
                85                  90                  95      


Cys Leu Lys His Arg Ser Cys Pro Pro Gly Phe Gly Val Val Gln Ala 
            100                 105                 110         


Gly Thr Pro Glu Arg Asn Thr Val Cys Lys Arg Cys Pro Asp Gly Phe 
        115                 120                 125             


Phe Ser Asn Glu Thr Ser Ser Lys Ala Pro Cys Arg Lys His Thr Asn 
    130                 135                 140                 


Cys Ser Val Phe Gly Leu Leu Leu Thr Gln Lys Gly Asn Ala Thr His 
145                 150                 155                 160 


Asp Asn Ile Cys Ser Gly Asn Ser Glu Ser Thr Gln Lys Cys Gly Ile 
                165                 170                 175     


Asp Val Thr Leu Cys Glu Glu Ala Phe Phe Arg Phe Ala Val Pro Thr 
            180                 185                 190         


Lys Phe Thr Pro Asn Trp Leu Ser Val Leu Val Asp Asn Leu Pro Gly 
        195                 200                 205             


Thr Lys Val Asn Ala Glu Ser Val Glu Arg Ile Lys Arg Gln His Ser 
    210                 215                 220                 


Ser Gln Glu Gln Thr Phe Gln Leu Leu Lys Leu Trp Lys His Gln Asn 
225                 230                 235                 240 


Lys Asp Gln Asp Ile Val Lys Lys Ile Ile Gln Asp Ile Asp Leu Cys 
                245                 250                 255     


Glu Asn Ser Val Gln Arg His Ile Gly His Ala Asn Leu Thr Phe Glu 
            260                 265                 270         


Gln Leu Arg Ser Leu Met Glu Ser Leu Pro Gly Lys Lys Val Gly Ala 
        275                 280                 285             


Glu Asp Ile Glu Lys Thr Ile Lys Ala Cys Lys Pro Ser Asp Gln Ile 
    290                 295                 300                 


Leu Lys Leu Leu Ser Leu Trp Arg Ile Lys Asn Gly Asp Gln Asp Thr 
305                 310                 315                 320 


Leu Lys Gly Leu Met His Ala Leu Lys His Ser Lys Thr Tyr His Phe 
                325                 330                 335     


Pro Lys Thr Val Thr Gln Ser Leu Lys Lys Thr Ile Arg Phe Leu His 
            340                 345                 350         


Ser Phe Thr Met Tyr Lys Leu Tyr Gln Lys Leu Phe Leu Glu Met Ile 
        355                 360                 365             


Gly Asn Gln Val Gln Ser Val Lys Ile Ser Cys Leu 
    370                 375                 380 


<210>  1292
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1292

Glu Gln Ala Pro Gly Thr Ala Pro Cys Ser Arg Gly Ser Ser Trp Ser 
1               5                   10                  15      


Ala Asp Leu Asp Lys Cys Met Asp Cys Ala Ser Cys Arg Ala Arg Pro 
            20                  25                  30          


His Ser Asp Phe Cys Leu Gly Cys Ala Ala Ala Pro Pro Ala Pro Phe 
        35                  40                  45              


Arg Leu Leu Trp Pro 
    50              


<210>  1293
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1293

Met Ser Gly Leu Gly Arg Ser Arg Arg Gly Gly Arg Ser Arg Val Asp 
1               5                   10                  15      


Gln Glu Glu Arg Trp Ser Leu Ser Cys Arg Lys Glu Gln Gly Lys Phe 
            20                  25                  30          


Tyr Asp His Leu Leu Arg Asp Cys Ile Ser Cys Ala Ser Ile Cys Gly 
        35                  40                  45              


Gln His Pro Lys Gln Cys Ala Tyr Phe Cys Glu Asn Lys Leu Arg Ser 
    50                  55                  60                  


Pro Val Asn Leu Pro Pro Glu Leu Arg Arg Gln Arg Ser Gly Glu Val 
65                  70                  75                  80  


Glu Asn Asn Ser Asp Asn Ser Gly Arg Tyr Gln Gly Leu Glu His Arg 
                85                  90                  95      


Gly Ser Glu Ala Ser Pro Ala Leu Pro Gly Leu Lys Leu Ser Ala Asp 
            100                 105                 110         


Gln Val Ala Leu Val Tyr Ser 
        115                 


<210>  1294
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  1294

Met Arg Arg Gly Pro Arg Ser Leu Arg Gly Arg Asp Ala Pro Ala Pro 
1               5                   10                  15      


Thr Pro Cys Val Pro Ala Glu Cys Phe Asp Leu Leu Val Arg His Cys 
            20                  25                  30          


Val Ala Cys Gly Leu Leu Arg Thr Pro Arg Pro Lys Pro Ala Gly Ala 
        35                  40                  45              


Ser Ser Pro Ala Pro Arg Thr Ala Leu Gln Pro Gln Glu Ser Val Gly 
    50                  55                  60                  


Ala Gly Ala Gly Glu Ala Ala Leu Pro Leu Pro Gly Leu Leu 
65                  70                  75              


<210>  1295
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  1295

Leu Pro Ser Cys Lys Glu Asp Glu Tyr Pro Val Gly Ser Glu Cys Cys 
1               5                   10                  15      


Pro Lys Cys Ser Pro Gly Tyr Arg Val Lys Glu Ala Cys Gly Glu Leu 
            20                  25                  30          


Thr Gly Thr Val Cys Glu Pro Cys Pro Pro Gly Thr Tyr Ile Ala His 
        35                  40                  45              


Leu Asn Gly Leu Ser Lys Cys Leu Gln Cys Gln Met Cys Asp Pro Ala 
    50                  55                  60                  


Met Gly Leu Arg Ala Ser Arg Asn Cys Ser Arg Thr Glu Asn Ala Val 
65                  70                  75                  80  


Cys Gly Cys Ser Pro Gly His Phe Cys Ile Val Gln Asp Gly Asp His 
                85                  90                  95      


Cys Ala Ala Cys Arg Ala Tyr Ala Thr Ser Ser Pro Gly Gln Arg Val 
            100                 105                 110         


Gln Lys Gly Gly Thr Glu Ser Gln Asp Thr Leu Cys Gln Asn Cys Pro 
        115                 120                 125             


Pro Gly Thr Leu Ser Pro Asn Gly Thr Leu Glu Glu Cys Gln His Gln 
    130                 135                 140                 


Thr Lys Cys Ser Trp Leu Val Thr Lys Ala Gly Ala Gly Thr Ser Ser 
145                 150                 155                 160 


Ser His Trp Val 
                


<210>  1296
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  1296

Met Leu Gln Met Ala Gly Gln Cys Ser Gln Asn Glu Tyr Phe Asp Ser 
1               5                   10                  15      


Leu Leu His Ala Cys Ile Pro Cys Gln Leu Arg Cys Ser Ser Asn Thr 
            20                  25                  30          


Pro Pro Leu Thr Cys Gln Arg Tyr Cys Asn Ala Ser Val Thr Asn Ser 
        35                  40                  45              


Val Lys Gly Thr Asn Ala 
    50                  


<210>  1297
<211>  141
<212>  PRT
<213>  Homo Sapiens

<400>  1297

Glu Ser Gly Asp Cys Arg Gln Gln Glu Phe Arg Asp Arg Ser Gly Asn 
1               5                   10                  15      


Cys Val Pro Cys Asn Gln Cys Gly Pro Gly Met Glu Leu Ser Lys Glu 
            20                  25                  30          


Cys Gly Phe Gly Tyr Gly Glu Asp Ala Gln Cys Val Thr Cys Arg Leu 
        35                  40                  45              


His Arg Phe Lys Glu Asp Trp Gly Phe Gln Lys Cys Lys Pro Cys Leu 
    50                  55                  60                  


Asp Cys Ala Val Val Asn Arg Phe Gln Lys Ala Asn Cys Ser Ala Thr 
65                  70                  75                  80  


Ser Asp Ala Ile Cys Gly Asp Cys Leu Pro Gly Phe Tyr Arg Lys Thr 
                85                  90                  95      


Lys Leu Val Gly Phe Gln Asp Met Glu Cys Val Pro Cys Gly Asp Pro 
            100                 105                 110         


Pro Pro Pro Tyr Glu Pro His Cys Ala Ser Lys Val Asn Leu Val Lys 
        115                 120                 125             


Ile Ala Ser Thr Ala Ser Ser Pro Arg Asp Thr Ala Leu 
    130                 135                 140     


<210>  1298
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  1298

Ser Thr Thr Leu Trp Gln Cys Pro Pro Gly Glu Glu Pro Asp Leu Asp 
1               5                   10                  15      


Pro Gly Gln Gly Thr Leu Cys Arg Pro Cys Pro Pro Gly Thr Phe Ser 
            20                  25                  30          


Ala Ala Trp Gly Ser Ser Pro Cys Gln Pro His Ala Arg Cys Ser Leu 
        35                  40                  45              


Trp Arg Arg Leu Glu Ala Gln Val Gly Met Ala Thr Arg Asp Thr Leu 
    50                  55                  60                  


Cys Gly Asp Cys Trp Pro Gly Trp Phe Gly Pro Trp Gly Val Pro Arg 
65                  70                  75                  80  


Val Pro Cys Gln Pro Cys Ser Trp Ala Pro Leu Gly Thr His Gly Cys 
                85                  90                  95      


Asp Glu Trp Gly Arg Arg Ala Arg Arg Gly Val Glu Val Ala Ala Gly 
            100                 105                 110         


Ala Ser Ser Gly Gly Glu Thr Arg Gln Pro Gly Asn Gly Thr Arg Ala 
        115                 120                 125             


Gly Gly Pro Glu Glu Thr Ala Ala Gln 
    130                 135         


<210>  1299
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  1299

Asp Ser Val Cys Pro Gln Gly Lys Tyr Ile His Pro Gln Asn Asn Ser 
1               5                   10                  15      


Ile Cys Cys Thr Lys Cys His Lys Gly Thr Tyr Leu Tyr Asn Asp Cys 
            20                  25                  30          


Pro Gly Pro Gly Gln Asp Thr Asp Cys Arg Glu Cys Glu Ser Gly Ser 
        35                  40                  45              


Phe Thr Ala Ser Glu Asn His Leu Arg His Cys Leu Ser Cys Ser Lys 
    50                  55                  60                  


Cys Arg Lys Glu Met Gly Gln Val Glu Ile Ser Ser Cys Thr Val Asp 
65                  70                  75                  80  


Arg Asp Thr Val Cys Gly Cys Arg Lys Asn Gln Tyr Arg His Tyr Trp 
                85                  90                  95      


Ser Glu Asn Leu Phe Gln Cys Phe Asn Cys Ser Leu Cys Leu Asn Gly 
            100                 105                 110         


Thr Val His Leu Ser Cys Gln Glu Lys Gln Asn Thr Val Cys Thr Cys 
        115                 120                 125             


His Ala Gly Phe Phe Leu Arg Glu Asn Glu Cys Val Ser Cys Ser Asn 
    130                 135                 140                 


Cys Lys Lys Ser Leu Glu Cys Thr Lys Leu Cys Leu Pro Gln Ile Glu 
145                 150                 155                 160 


Asn 
    


<210>  1300
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1300

Leu Pro Ala Gln Val Ala Phe Thr Pro Tyr Ala Pro Glu Pro Gly Ser 
1               5                   10                  15      


Thr Cys Arg Leu Arg Glu Tyr Tyr Asp Gln Thr Ala Gln Met Cys Cys 
            20                  25                  30          


Ser Lys Cys Ser Pro Gly Gln His Ala Lys Val Phe Cys Thr Lys Thr 
        35                  40                  45              


Ser Asp Thr Val Cys Asp Ser Cys Glu Asp Ser Thr Tyr Thr Gln Leu 
    50                  55                  60                  


Trp Asn Trp Val Pro Glu Cys Leu Ser Cys Gly Ser Arg Cys Ser Ser 
65                  70                  75                  80  


Asp Gln Val Glu Thr Gln Ala Cys Thr Arg Glu Gln Asn Arg Ile Cys 
                85                  90                  95      


Thr Cys Arg Pro Gly Trp Tyr Cys Ala Leu Ser Lys Gln Glu Gly Cys 
            100                 105                 110         


Arg Leu Cys Ala Pro Leu Arg Lys Cys Arg Pro Gly Phe Gly Val Ala 
        115                 120                 125             


Arg Pro Gly Thr Glu Thr Ser Asp Val Val Cys Lys Pro Cys Ala Pro 
    130                 135                 140                 


Gly Thr Phe Ser Asn Thr Thr Ser Ser Thr Asp Ile Cys Arg Pro His 
145                 150                 155                 160 


Gln Ile Cys Asn Val Val Ala Ile Pro Gly Asn Ala Ser Met Asp Ala 
                165                 170                 175     


Val Cys Thr Ser Thr Ser Pro Thr Arg Ser Met Ala Pro Gly Ala Val 
            180                 185                 190         


His Leu Pro Gln Pro Val Ser Thr Arg Ser Gln His Thr Gln Pro Thr 
        195                 200                 205             


Pro Glu Pro Ser Thr Ala Pro Ser Thr Ser Phe Leu Leu Pro Met Gly 
    210                 215                 220                 


Pro Ser Pro Pro Ala Glu Gly Ser Thr Gly Asp 
225                 230                 235 


<210>  1301
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  1301

Gln Pro Glu Gln Lys Ala Ser Asn Leu Ile Gly Thr Tyr Arg His Val 
1               5                   10                  15      


Asp Arg Ala Thr Gly Gln Val Leu Thr Cys Asp Lys Cys Pro Ala Gly 
            20                  25                  30          


Thr Tyr Val Ser Glu His Cys Thr Asn Thr Ser Leu Arg Val Cys Ser 
        35                  40                  45              


Ser Cys Pro Val Gly Thr Phe Thr Arg His Glu Asn Gly Ile Glu Lys 
    50                  55                  60                  


Cys His Asp Cys Ser Gln Pro Cys Pro Trp Pro Met Ile Glu Lys Leu 
65                  70                  75                  80  


Pro Cys Ala Ala Leu Thr Asp Arg Glu Cys Thr Cys Pro Pro Gly Met 
                85                  90                  95      


Phe Gln Ser Asn Ala Thr Cys Ala Pro His Thr Val Cys Pro Val Gly 
            100                 105                 110         


Trp Gly Val Arg Lys Lys Gly Thr Glu Thr Glu Asp Val Arg Cys Lys 
        115                 120                 125             


Gln Cys Ala Arg Gly Thr Phe Ser Asp Val Pro Ser Ser Val Met Lys 
    130                 135                 140                 


Cys Lys Ala Tyr Thr Asp Cys Leu Ser Gln Asn Leu Val Val Ile Lys 
145                 150                 155                 160 


Pro Gly Thr Lys Glu Thr Asp Asn Val Cys Gly Thr Leu Pro Ser Phe 
                165                 170                 175     


Ser Ser Ser Thr Ser Pro Ser Pro Gly Thr Ala Ile Phe Pro Arg Pro 
            180                 185                 190         


Glu His Met Glu Thr His Glu Val Pro Ser Ser Thr Tyr Val Pro Lys 
        195                 200                 205             


Gly Met Asn Ser Thr Glu Ser Asn Ser Ser Ala Ser Val Arg Pro Lys 
    210                 215                 220                 


Val Leu Ser Ser Ile Gln Glu Gly Thr Val Pro Asp Asn Thr Ser Ser 
225                 230                 235                 240 


Ala Arg Gly Lys Glu Asp Val Asn Lys Thr Leu Pro Asn Leu Gln Val 
                245                 250                 255     


Val Asn His Gln Gln Gly Pro His His Arg His Ile Leu Lys Leu Leu 
            260                 265                 270         


Pro Ser Met Glu Ala Thr Gly Gly Glu Lys Ser Ser Thr Pro Ile Lys 
        275                 280                 285             


Gly Pro Lys Arg Gly His Pro Arg Gln Asn Leu His Lys His Phe Asp 
    290                 295                 300                 


Ile Asn Glu His 
305             


<210>  1302
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  1302

Gln Gly Gly Thr Arg Ser Pro Arg Cys Asp Cys Ala Gly Asp Phe His 
1               5                   10                  15      


Lys Lys Ile Gly Leu Phe Cys Cys Arg Gly Cys Pro Ala Gly His Tyr 
            20                  25                  30          


Leu Lys Ala Pro Cys Thr Glu Pro Cys Gly Asn Ser Thr Cys Leu Val 
        35                  40                  45              


Cys Pro Gln Asp Thr Phe Leu Ala Trp Glu Asn His His Asn Ser Glu 
    50                  55                  60                  


Cys Ala Arg Cys Gln Ala Cys Asp Glu Gln Ala Ser Gln Val Ala Leu 
65                  70                  75                  80  


Glu Asn Cys Ser Ala Val Ala Asp Thr Arg Cys Gly Cys Lys Pro Gly 
                85                  90                  95      


Trp Phe Val Glu Cys Gln Val Ser Gln Cys Val Ser Ser Ser Pro Phe 
            100                 105                 110         


Tyr Cys Gln Pro Cys Leu Asp Cys Gly Ala Leu His Arg His Thr Arg 
        115                 120                 125             


Leu Leu Cys Ser Arg Arg Asp Thr Asp Cys Gly Thr Cys Leu Pro Gly 
    130                 135                 140                 


Phe Tyr Glu His Gly Asp Gly Cys Val Ser Cys Pro Thr Ser Thr Leu 
145                 150                 155                 160 


Gly Ser Cys Pro Glu Arg Cys Ala Ala Val Cys Gly Trp Arg Gln 
                165                 170                 175 


<210>  1303
<211>  186
<212>  PRT
<213>  Homo Sapiens

<400>  1303

Leu His Cys Val Gly Asp Thr Tyr Pro Ser Asn Asp Arg Cys Cys His 
1               5                   10                  15      


Glu Cys Arg Pro Gly Asn Gly Met Val Ser Arg Cys Ser Arg Ser Gln 
            20                  25                  30          


Asn Thr Val Cys Arg Pro Cys Gly Pro Gly Phe Tyr Asn Asp Val Val 
        35                  40                  45              


Ser Ser Lys Pro Cys Lys Pro Cys Thr Trp Cys Asn Leu Arg Ser Gly 
    50                  55                  60                  


Ser Glu Arg Lys Gln Leu Cys Thr Ala Thr Gln Asp Thr Val Cys Arg 
65                  70                  75                  80  


Cys Arg Ala Gly Thr Gln Pro Leu Asp Ser Tyr Lys Pro Gly Val Asp 
                85                  90                  95      


Cys Ala Pro Cys Pro Pro Gly His Phe Ser Pro Gly Asp Asn Gln Ala 
            100                 105                 110         


Cys Lys Pro Trp Thr Asn Cys Thr Leu Ala Gly Lys His Thr Leu Gln 
        115                 120                 125             


Pro Ala Ser Asn Ser Ser Asp Ala Ile Cys Glu Asp Arg Asp Pro Pro 
    130                 135                 140                 


Ala Thr Gln Pro Gln Glu Thr Gln Gly Pro Pro Ala Arg Pro Ile Thr 
145                 150                 155                 160 


Val Gln Pro Thr Glu Ala Trp Pro Arg Thr Ser Gln Gly Pro Ser Thr 
                165                 170                 175     


Arg Pro Val Glu Val Pro Gly Gly Arg Ala 
            180                 185     


<210>  1304
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  1304

Glu Pro Pro Thr Ala Cys Arg Glu Lys Gln Tyr Leu Ile Asn Ser Gln 
1               5                   10                  15      


Cys Cys Ser Leu Cys Gln Pro Gly Gln Lys Leu Val Ser Asp Cys Thr 
            20                  25                  30          


Glu Phe Thr Glu Thr Glu Cys Leu Pro Cys Gly Glu Ser Glu Phe Leu 
        35                  40                  45              


Asp Thr Trp Asn Arg Glu Thr His Cys His Gln His Lys Tyr Cys Asp 
    50                  55                  60                  


Pro Asn Leu Gly Leu Arg Val Gln Gln Lys Gly Thr Ser Glu Thr Asp 
65                  70                  75                  80  


Thr Ile Cys Thr Cys Glu Glu Gly Trp His Cys Thr Ser Glu Ala Cys 
                85                  90                  95      


Glu Ser Cys Val Leu His Arg Ser Cys Ser Pro Gly Phe Gly Val Lys 
            100                 105                 110         


Gln Ile Ala Thr Gly Val Ser Asp Thr Ile Cys Glu Pro Cys Pro Val 
        115                 120                 125             


Gly Phe Phe Ser Asn Val Ser Ser Ala Phe Glu Lys Cys His Pro Trp 
    130                 135                 140                 


Thr Ser Cys Glu Thr Lys Asp Leu Val Val Gln Gln Ala Gly Thr Asn 
145                 150                 155                 160 


Lys Thr Asp Val Val Cys Gly Pro Gln Asp Arg Leu Arg 
                165                 170             


<210>  1305
<211>  148
<212>  PRT
<213>  Homo Sapiens

<400>  1305

Gln Val Thr Asp Ile Asn Ser Lys Gly Leu Glu Leu Arg Lys Thr Val 
1               5                   10                  15      


Thr Thr Val Glu Thr Gln Asn Leu Glu Gly Leu His His Asp Gly Gln 
            20                  25                  30          


Phe Cys His Lys Pro Cys Pro Pro Gly Glu Arg Lys Ala Arg Asp Cys 
        35                  40                  45              


Thr Val Asn Gly Asp Glu Pro Asp Cys Val Pro Cys Gln Glu Gly Lys 
    50                  55                  60                  


Glu Tyr Thr Asp Lys Ala His Phe Ser Ser Lys Cys Arg Arg Cys Arg 
65                  70                  75                  80  


Leu Cys Asp Glu Gly His Gly Leu Glu Val Glu Ile Asn Cys Thr Arg 
                85                  90                  95      


Thr Gln Asn Thr Lys Cys Arg Cys Lys Pro Asn Phe Phe Cys Asn Ser 
            100                 105                 110         


Thr Val Cys Glu His Cys Asp Pro Cys Thr Lys Cys Glu His Gly Ile 
        115                 120                 125             


Ile Lys Glu Cys Thr Leu Thr Ser Asn Thr Lys Cys Lys Glu Glu Gly 
    130                 135                 140                 


Ser Arg Ser Asn 
145             


<210>  1306
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  1306

Val Ala Glu Thr Pro Thr Tyr Pro Trp Arg Asp Ala Glu Thr Gly Glu 
1               5                   10                  15      


Arg Leu Val Cys Ala Gln Cys Pro Pro Gly Thr Phe Val Gln Arg Pro 
            20                  25                  30          


Cys Arg Arg Asp Ser Pro Thr Thr Cys Gly Pro Cys Pro Pro Arg His 
        35                  40                  45              


Tyr Thr Gln Phe Trp Asn Tyr Leu Glu Arg Cys Arg Tyr Cys Asn Val 
    50                  55                  60                  


Leu Cys Gly Glu Arg Glu Glu Glu Ala Arg Ala Cys His Ala Thr His 
65                  70                  75                  80  


Asn Arg Ala Cys Arg Cys Arg Thr Gly Phe Phe Ala His Ala Gly Phe 
                85                  90                  95      


Cys Leu Glu His Ala Ser Cys Pro Pro Gly Ala Gly Val Ile Ala Pro 
            100                 105                 110         


Gly Thr Pro Ser Gln Asn Thr Gln Cys Gln Pro Cys Pro Pro Gly Thr 
        115                 120                 125             


Phe Ser Ala Ser Ser Ser Ser Ser Glu Gln Cys Gln Pro His Arg Asn 
    130                 135                 140                 


Cys Thr Ala Leu Gly Leu Ala Leu Asn Val Pro Gly Ser Ser Ser His 
145                 150                 155                 160 


Asp Thr Leu Cys Thr Ser Cys Thr Gly Phe Pro Leu Ser Thr Arg Val 
                165                 170                 175     


Pro Gly Ala Glu Glu Cys Glu Arg Ala Val Ile Asp Phe Val Ala Phe 
            180                 185                 190         


Gln Asp Ile Ser Ile Lys Arg Leu Gln Arg Leu Leu Gln Ala Leu Glu 
        195                 200                 205             


Ala Pro Glu Gly Trp Gly Pro Thr Pro Arg Ala Gly Arg Ala Ala Leu 
    210                 215                 220                 


Gln Leu Lys Leu Arg Arg Arg Leu Thr Glu Leu Leu Gly Ala Gln Asp 
225                 230                 235                 240 


Gly Ala Leu Leu Val Arg Leu Leu Gln Ala Leu Arg Val Ala Arg Met 
                245                 250                 255     


Pro Gly Leu Glu Arg Ser Val Arg Glu Arg Phe Leu Pro Val His 
            260                 265                 270     


<210>  1307
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  1307

Ala Thr Pro Ala Pro Lys Ser Cys Pro Glu Arg His Tyr Trp Ala Gln 
1               5                   10                  15      


Gly Lys Leu Cys Cys Gln Met Cys Glu Pro Gly Thr Phe Leu Val Lys 
            20                  25                  30          


Asp Cys Asp Gln His Arg Lys Ala Ala Gln Cys Asp Pro Cys Ile Pro 
        35                  40                  45              


Gly Val Ser Phe Ser Pro Asp His His Thr Arg Pro His Cys Glu Ser 
    50                  55                  60                  


Cys Arg His Cys Asn Ser Gly Leu Leu Val Arg Asn Cys Thr Ile Thr 
65                  70                  75                  80  


Ala Asn Ala Glu Cys Ala Cys Arg Asn Gly Trp Gln Cys Arg Asp Lys 
                85                  90                  95      


Glu Cys Thr Glu Cys Asp Pro Leu Pro Asn Pro Ser Leu Thr Ala Arg 
            100                 105                 110         


Ser Ser Gln Ala Leu Ser Pro His Pro Gln Pro Thr His Leu Pro Tyr 
        115                 120                 125             


Val Ser Glu Met Leu Glu Ala Arg Thr Ala Gly His Met Gln Thr Leu 
    130                 135                 140                 


Ala Asp Phe Arg Gln Leu Pro Ala Arg Thr Leu Ser Thr His Trp Pro 
145                 150                 155                 160 


Pro Gln Arg Ser Leu Cys Ser Ser Asp Phe Ile Arg 
                165                 170         


<210>  1308
<211>  361
<212>  PRT
<213>  Homo Sapiens

<400>  1308

Phe Pro Gln Asp Arg Pro Phe Glu Asp Thr Cys His Gly Asn Pro Ser 
1               5                   10                  15      


His Tyr Tyr Asp Lys Ala Val Arg Arg Cys Cys Tyr Arg Cys Pro Met 
            20                  25                  30          


Gly Leu Phe Pro Thr Gln Gln Cys Pro Gln Arg Pro Thr Asp Cys Arg 
        35                  40                  45              


Lys Gln Cys Glu Pro Asp Tyr Tyr Leu Asp Glu Ala Asp Arg Cys Thr 
    50                  55                  60                  


Ala Cys Val Thr Cys Ser Arg Asp Asp Leu Val Glu Lys Thr Pro Cys 
65                  70                  75                  80  


Ala Trp Asn Ser Ser Arg Val Cys Glu Cys Arg Pro Gly Met Phe Cys 
                85                  90                  95      


Ser Thr Ser Ala Val Asn Ser Cys Ala Arg Cys Phe Phe His Ser Val 
            100                 105                 110         


Cys Pro Ala Gly Met Ile Val Lys Phe Pro Gly Thr Ala Gln Lys Asn 
        115                 120                 125             


Thr Val Cys Glu Pro Ala Ser Pro Gly Val Ser Pro Ala Cys Ala Ser 
    130                 135                 140                 


Pro Glu Asn Cys Lys Glu Pro Ser Ser Gly Thr Ile Pro Gln Ala Lys 
145                 150                 155                 160 


Pro Thr Pro Val Ser Pro Ala Thr Ser Ser Ala Ser Thr Met Pro Val 
                165                 170                 175     


Arg Gly Gly Thr Arg Leu Ala Gln Glu Ala Ala Ser Lys Leu Thr Arg 
            180                 185                 190         


Ala Pro Asp Ser Pro Ser Ser Val Gly Arg Pro Ser Ser Asp Pro Gly 
        195                 200                 205             


Leu Ser Pro Thr Gln Pro Cys Pro Glu Gly Ser Gly Asp Cys Arg Lys 
    210                 215                 220                 


Gln Cys Glu Pro Asp Tyr Tyr Leu Asp Glu Ala Gly Arg Cys Thr Ala 
225                 230                 235                 240 


Cys Val Ser Cys Ser Arg Asp Asp Leu Val Glu Lys Thr Pro Cys Ala 
                245                 250                 255     


Trp Asn Ser Ser Arg Thr Cys Glu Cys Arg Pro Gly Met Ile Cys Ala 
            260                 265                 270         


Thr Ser Ala Thr Asn Ser Cys Ala Arg Cys Val Pro Tyr Pro Ile Cys 
        275                 280                 285             


Ala Ala Glu Thr Val Thr Lys Pro Gln Asp Met Ala Glu Lys Asp Thr 
    290                 295                 300                 


Thr Phe Glu Ala Pro Pro Leu Gly Thr Gln Pro Asp Cys Asn Pro Thr 
305                 310                 315                 320 


Pro Glu Asn Gly Glu Ala Pro Ala Ser Thr Ser Pro Thr Gln Ser Leu 
                325                 330                 335     


Leu Val Asp Ser Gln Ala Ser Lys Thr Leu Pro Ile Pro Thr Ser Ala 
            340                 345                 350         


Pro Val Ala Leu Ser Ser Thr Gly Lys 
        355                 360     


<210>  1309
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  1309

Leu Gln Asp Pro Cys Ser Asn Cys Pro Ala Gly Thr Phe Cys Asp Asn 
1               5                   10                  15      


Asn Arg Asn Gln Ile Cys Ser Pro Cys Pro Pro Asn Ser Phe Ser Ser 
            20                  25                  30          


Ala Gly Gly Gln Arg Thr Cys Asp Ile Cys Arg Gln Cys Lys Gly Val 
        35                  40                  45              


Phe Arg Thr Arg Lys Glu Cys Ser Ser Thr Ser Asn Ala Glu Cys Asp 
    50                  55                  60                  


Cys Thr Pro Gly Phe His Cys Leu Gly Ala Gly Cys Ser Met Cys Glu 
65                  70                  75                  80  


Gln Asp Cys Lys Gln Gly Gln Glu Leu Thr Lys Lys Gly Cys Lys Asp 
                85                  90                  95      


Cys Cys Phe Gly Thr Phe Asn Asp Gln Lys Arg Gly Ile Cys Arg Pro 
            100                 105                 110         


Trp Thr Asn Cys Ser Leu Asp Gly Lys Ser Val Leu Val Asn Gly Thr 
        115                 120                 125             


Lys Glu Arg Asp Val Val Cys Gly Pro Ser Pro Ala Asp Leu Ser Pro 
    130                 135                 140                 


Gly Ala Ser Ser Val Thr Pro Pro Ala Pro Ala Arg Glu Pro Gly His 
145                 150                 155                 160 


Ser Pro Gln 
            


<210>  1310
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  1310

Thr Asn Glu Leu Lys Gln Met Gln Asp Lys Tyr Ser Lys Ser Gly Ile 
1               5                   10                  15      


Ala Cys Phe Leu Lys Glu Asp Asp Ser Tyr Trp Asp Pro Asn Asp Glu 
            20                  25                  30          


Glu Ser Met Asn Ser Pro Cys Trp Gln Val Lys Trp Gln Leu Arg Gln 
        35                  40                  45              


Leu Val Arg Lys Met Ile Leu Arg Thr Ser Glu Glu Thr Ile Ser Thr 
    50                  55                  60                  


Val Gln Glu Lys Gln Gln Asn Ile Ser Pro Leu Val Arg Glu Arg Gly 
65                  70                  75                  80  


Pro Gln Arg Val Ala Ala His Ile Thr Gly Thr Arg Gly Arg Ser Asn 
                85                  90                  95      


Thr Leu Ser Ser Pro Asn Ser Lys Asn Glu Lys Ala Leu Gly Arg Lys 
            100                 105                 110         


Ile Asn Ser Trp Glu Ser Ser Arg Ser Gly His Ser Phe Leu Ser Asn 
        115                 120                 125             


Leu His Leu Arg Asn Gly Glu Leu Val Ile His Glu Lys Gly Phe Tyr 
    130                 135                 140                 


Tyr Ile Tyr Ser Gln Thr Tyr Phe Arg Phe Gln Glu Glu Ile Lys Glu 
145                 150                 155                 160 


Asn Thr Lys Asn Asp Lys Gln Met Val Gln Tyr Ile Tyr Lys Tyr Thr 
                165                 170                 175     


Ser Tyr Pro Asp Pro Ile Leu Leu Met Lys Ser Ala Arg Asn Ser Cys 
            180                 185                 190         


Trp Ser Lys Asp Ala Glu Tyr Gly Leu Tyr Ser Ile Tyr Gln Gly Gly 
        195                 200                 205             


Ile Phe Glu Leu Lys Glu Asn Asp Arg Ile Phe Val Ser Val Thr Asn 
    210                 215                 220                 


Glu His Leu Ile Asp Met Asp His Glu Ala Ser Phe Phe Gly Ala Phe 
225                 230                 235                 240 


Leu Val Gly 
            


<210>  1311
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  1311

Ile Arg Ala Glu Lys Ala Met Val Asp Gly Ser Trp Leu Asp Leu Ala 
1               5                   10                  15      


Lys Arg Ser Lys Leu Glu Ala Gln Pro Phe Ala His Leu Thr Ile Asn 
            20                  25                  30          


Ala Thr Asp Ile Pro Ser Gly Ser His Lys Val Ser Leu Ser Ser Trp 
        35                  40                  45              


Tyr His Asp Arg Gly Trp Ala Lys Ile Ser Asn Met Thr Phe Ser Asn 
    50                  55                  60                  


Gly Lys Leu Ile Val Asn Gln Asp Gly Phe Tyr Tyr Leu Tyr Ala Asn 
65                  70                  75                  80  


Ile Cys Phe Arg His His Glu Thr Ser Gly Asp Leu Ala Thr Glu Tyr 
                85                  90                  95      


Leu Gln Leu Met Val Tyr Val Thr Lys Thr Ser Ile Lys Ile Pro Ser 
            100                 105                 110         


Ser His Thr Leu Met Lys Gly Gly Ser Thr Lys Tyr Trp Ser Gly Asn 
        115                 120                 125             


Ser Glu Phe His Phe Tyr Ser Ile Asn Val Gly Gly Phe Phe Lys Leu 
    130                 135                 140                 


Arg Ser Gly Glu Glu Ile Ser Ile Glu Val Ser Asn Pro Ser Leu Leu 
145                 150                 155                 160 


Asp Pro Asp Gln Asp Ala Thr Tyr Phe Gly Ala Phe Lys Val Arg Asp 
                165                 170                 175     


Ile Asp 
        


<210>  1312
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  1312

Ser Ala Pro Lys Gly Arg Lys Thr Arg Ala Arg Arg Ala Ile Ala Ala 
1               5                   10                  15      


His Tyr Glu Val His Pro Arg Pro Gly Gln Asp Gly Ala Gln Ala Gly 
            20                  25                  30          


Val Asp Gly Thr Val Ser Gly Trp Glu Glu Ala Arg Ile Asn Ser Ser 
        35                  40                  45              


Ser Pro Leu Arg Tyr Asn Arg Gln Ile Gly Glu Phe Ile Val Thr Arg 
    50                  55                  60                  


Ala Gly Leu Tyr Tyr Leu Tyr Cys Gln Val His Phe Asp Glu Gly Lys 
65                  70                  75                  80  


Ala Val Tyr Leu Lys Leu Asp Leu Leu Val Asp Gly Val Leu Ala Leu 
                85                  90                  95      


Arg Cys Leu Glu Glu Phe Ser Ala Thr Ala Ala Ser Ser Leu Gly Pro 
            100                 105                 110         


Gln Leu Arg Leu Cys Gln Val Ser Gly Leu Leu Ala Leu Arg Pro Gly 
        115                 120                 125             


Ser Ser Leu Arg Ile Arg Thr Leu Pro Trp Ala His Leu Lys Ala Ala 
    130                 135                 140                 


Pro Phe Leu Thr Tyr Phe Gly Leu Phe Gln Val His 
145                 150                 155     


<210>  1313
<211>  146
<212>  PRT
<213>  Homo Sapiens

<400>  1313

Ala Val Leu Thr Gln Lys Gln Lys Lys Gln His Ser Val Leu His Leu 
1               5                   10                  15      


Val Pro Ile Asn Ala Thr Ser Lys Asp Asp Ser Asp Val Thr Glu Val 
            20                  25                  30          


Met Trp Gln Pro Ala Leu Arg Arg Gly Arg Gly Leu Gln Ala Gln Gly 
        35                  40                  45              


Tyr Gly Val Arg Ile Gln Asp Ala Gly Val Tyr Leu Leu Tyr Ser Gln 
    50                  55                  60                  


Val Leu Phe Gln Asp Val Thr Phe Thr Met Gly Gln Val Val Ser Arg 
65                  70                  75                  80  


Glu Gly Gln Gly Arg Gln Glu Thr Leu Phe Arg Cys Ile Arg Ser Met 
                85                  90                  95      


Pro Ser His Pro Asp Arg Ala Tyr Asn Ser Cys Tyr Ser Ala Gly Val 
            100                 105                 110         


Phe His Leu His Gln Gly Asp Ile Leu Ser Val Ile Ile Pro Arg Ala 
        115                 120                 125             


Arg Ala Lys Leu Asn Leu Ser Pro His Gly Thr Phe Leu Gly Phe Val 
    130                 135                 140                 


Lys Leu 
145     


<210>  1314
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  1314

Ala Val Gln Gly Pro Glu Glu Thr Val Thr Gln Asp Cys Leu Gln Leu 
1               5                   10                  15      


Ile Ala Asp Ser Glu Thr Pro Thr Ile Gln Lys Gly Ser Tyr Thr Phe 
            20                  25                  30          


Val Pro Trp Leu Leu Ser Phe Lys Arg Gly Ser Ala Leu Glu Glu Lys 
        35                  40                  45              


Glu Asn Lys Ile Leu Val Lys Glu Thr Gly Tyr Phe Phe Ile Tyr Gly 
    50                  55                  60                  


Gln Val Leu Tyr Thr Asp Lys Thr Tyr Ala Met Gly His Leu Ile Gln 
65                  70                  75                  80  


Arg Lys Lys Val His Val Phe Gly Asp Glu Leu Ser Leu Val Thr Leu 
                85                  90                  95      


Phe Arg Cys Ile Gln Asn Met Pro Glu Thr Leu Pro Asn Asn Ser Cys 
            100                 105                 110         


Tyr Ser Ala Gly Ile Ala Lys Leu Glu Glu Gly Asp Glu Leu Gln Leu 
        115                 120                 125             


Ala Ile Pro Arg Glu Asn Ala Gln Ile Ser Leu Asp Gly Asp Val Thr 
    130                 135                 140                 


Phe Phe Gly Ala Leu Lys Leu Leu 
145                 150         


<210>  1315
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  1315

Gln Glu Arg Arg Ser His Glu Val Asn Pro Ala Ala His Leu Thr Gly 
1               5                   10                  15      


Ala Asn Ser Ser Leu Thr Gly Ser Gly Gly Pro Leu Leu Trp Glu Thr 
            20                  25                  30          


Gln Leu Gly Leu Ala Phe Leu Arg Gly Leu Ser Tyr His Asp Gly Ala 
        35                  40                  45              


Leu Val Val Thr Lys Ala Gly Tyr Tyr Tyr Ile Tyr Ser Lys Val Gln 
    50                  55                  60                  


Leu Gly Gly Val Gly Cys Pro Leu Gly Leu Ala Ser Thr Ile Thr His 
65                  70                  75                  80  


Gly Leu Tyr Lys Arg Thr Pro Arg Tyr Pro Glu Glu Leu Glu Leu Leu 
                85                  90                  95      


Val Ser Gln Gln Ser Pro Cys Gly Arg Ala Thr Ser Ser Ser Arg Val 
            100                 105                 110         


Trp Trp Asp Ser Ser Phe Leu Gly Gly Val Val His Leu Glu Ala Gly 
        115                 120                 125             


Glu Lys Val Val Val Arg Val Leu Asp Glu Arg Leu Val Arg Leu Arg 
    130                 135                 140                 


Asp Gly Thr Arg Ser Tyr Phe Gly Ala Phe Met Val 
145                 150                 155     


<210>  1316
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  1316

Leu Lys Gly Gln Glu Phe Ala Pro Ser His Gln Gln Val Tyr Ala Pro 
1               5                   10                  15      


Leu Arg Ala Asp Gly Asp Lys Pro Arg Ala His Leu Thr Val Val Arg 
            20                  25                  30          


Gln Thr Pro Thr Gln His Phe Lys Asn Gln Phe Pro Ala Leu His Trp 
        35                  40                  45              


Glu His Glu Leu Gly Leu Ala Phe Thr Lys Asn Arg Met Asn Tyr Thr 
    50                  55                  60                  


Asn Lys Phe Leu Leu Ile Pro Glu Ser Gly Asp Tyr Phe Ile Tyr Ser 
65                  70                  75                  80  


Gln Val Thr Phe Arg Gly Met Thr Ser Glu Cys Ser Glu Ile Arg Gln 
                85                  90                  95      


Ala Gly Arg Pro Asn Lys Pro Asp Ser Ile Thr Val Val Ile Thr Lys 
            100                 105                 110         


Val Thr Asp Ser Tyr Pro Glu Pro Thr Gln Leu Leu Met Gly Thr Lys 
        115                 120                 125             


Ser Val Cys Glu Val Gly Ser Asn Trp Phe Gln Pro Ile Tyr Leu Gly 
    130                 135                 140                 


Ala Met Phe Ser Leu Gln Glu Gly Asp Lys Leu Met Val Asn Val Ser 
145                 150                 155                 160 


Asp Ile Ser Leu Val Asp Tyr Thr Lys Glu Asp Lys Thr Phe Phe Gly 
                165                 170                 175     


Ala Phe Leu Leu 
            180 


<210>  1317
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  1317

Gln Leu Glu Thr Ala Lys Glu Pro Cys Met Ala Lys Phe Gly Pro Leu 
1               5                   10                  15      


Pro Ser Lys Trp Gln Met Ala Ser Ser Glu Pro Pro Cys Val Asn Lys 
            20                  25                  30          


Val Ser Asp Trp Lys Leu Glu Ile Leu Gln Asn Gly Leu Tyr Leu Ile 
        35                  40                  45              


Tyr Gly Gln Val Ala Pro Asn Ala Asn Tyr Asn Asp Val Ala Pro Phe 
    50                  55                  60                  


Glu Val Arg Leu Tyr Lys Asn Lys Asp Met Ile Gln Thr Leu Thr Asn 
65                  70                  75                  80  


Lys Ser Lys Ile Gln Asn Val Gly Gly Thr Tyr Glu Leu His Val Gly 
                85                  90                  95      


Asp Thr Ile Asp Leu Ile Phe Asn Ser Glu His Gln Val Leu Lys Asn 
            100                 105                 110         


Asn Thr Tyr Trp Gly Ile Ile Leu Leu Ala Asn Pro Gln Phe Ile Ser 
        115                 120                 125             


<210>  1318
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  1318

Met Val Ser His Arg Tyr Pro Arg Ile Gln Ser Ile Lys Val Gln Phe 
1               5                   10                  15      


Thr Glu Tyr Lys Lys Glu Lys Gly Phe Ile Leu Thr Ser Gln Lys Glu 
            20                  25                  30          


Asp Glu Ile Met Lys Val Gln Asn Asn Ser Val Ile Ile Asn Cys Asp 
        35                  40                  45              


Gly Phe Tyr Leu Ile Ser Leu Lys Gly Tyr Phe Ser Gln Glu Val Asn 
    50                  55                  60                  


Ile Ser Leu His Tyr Gln Lys Asp Glu Glu Pro Leu Phe Gln Leu Lys 
65                  70                  75                  80  


Lys Val Arg Ser Val Asn Ser Leu Met Val Ala Ser Leu Thr Tyr Lys 
                85                  90                  95      


Asp Lys Val Tyr Leu Asn Val Thr Thr Asp Asn Thr Ser Leu Asp Asp 
            100                 105                 110         


Phe His Val Asn Gly Gly Glu Leu Ile Leu Ile His Gln Asn Pro Gly 
        115                 120                 125             


Glu Phe Cys Val Leu 
    130             


<210>  1319
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  1319

Gln Ile Gly His Pro Ser Pro Pro Pro Glu Lys Lys Glu Leu Arg Lys 
1               5                   10                  15      


Val Ala His Leu Thr Gly Lys Ser Asn Ser Arg Ser Met Pro Leu Glu 
            20                  25                  30          


Trp Glu Asp Thr Tyr Gly Ile Val Leu Leu Ser Gly Val Lys Tyr Lys 
        35                  40                  45              


Lys Gly Gly Leu Val Ile Asn Glu Thr Gly Leu Tyr Phe Val Tyr Ser 
    50                  55                  60                  


Lys Val Tyr Phe Arg Gly Gln Ser Cys Asn Asn Leu Pro Leu Ser His 
65                  70                  75                  80  


Lys Val Tyr Met Arg Asn Ser Lys Tyr Pro Gln Asp Leu Val Met Met 
                85                  90                  95      


Glu Gly Lys Met Met Ser Tyr Cys Thr Thr Gly Gln Met Trp Ala Arg 
            100                 105                 110         


Ser Ser Tyr Leu Gly Ala Val Phe Asn Leu Thr Ser Ala Asp His Leu 
        115                 120                 125             


Tyr Val Asn Val Ser Glu Leu Ser Leu Val Asn Phe Glu Glu Ser Gln 
    130                 135                 140                 


Thr Phe Phe Gly Leu Tyr Lys Leu 
145                 150         


<210>  1320
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  1320

Gln Arg Thr Asp Ser Ile Pro Asn Ser Pro Asp Asn Val Pro Leu Lys 
1               5                   10                  15      


Gly Gly Asn Cys Ser Glu Asp Leu Leu Cys Ile Leu Lys Arg Ala Pro 
            20                  25                  30          


Phe Lys Lys Ser Trp Ala Tyr Leu Gln Val Ala Lys His Leu Asn Lys 
        35                  40                  45              


Thr Lys Leu Ser Trp Asn Lys Asp Gly Ile Leu His Gly Val Arg Tyr 
    50                  55                  60                  


Gln Asp Gly Asn Leu Val Ile Gln Phe Pro Gly Leu Tyr Phe Ile Ile 
65                  70                  75                  80  


Cys Gln Leu Gln Phe Leu Val Gln Cys Pro Asn Asn Ser Val Asp Leu 
                85                  90                  95      


Lys Leu Glu Leu Leu Ile Asn Lys His Ile Lys Lys Gln Ala Leu Val 
            100                 105                 110         


Thr Val Cys Glu Ser Gly Met Gln Thr Lys His Val Tyr Gln Asn Leu 
        115                 120                 125             


Ser Gln Phe Leu Leu Asp Tyr Leu Gln Val Asn Thr Thr Ile Ser Val 
    130                 135                 140                 


Asn Val Asp Thr Phe Gln Tyr Ile Asp Thr Ser Thr Phe Pro Leu Glu 
145                 150                 155                 160 


Asn Val Leu Ser Ile Phe Leu Tyr Ser Asn Ser Asp 
                165                 170         


<210>  1321
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  1321

Ala Cys Pro Trp Ala Val Ser Gly Ala Arg Ala Ser Pro Gly Ser Ala 
1               5                   10                  15      


Ala Ser Pro Arg Leu Arg Glu Gly Pro Glu Leu Ser Pro Asp Asp Pro 
            20                  25                  30          


Ala Gly Leu Leu Asp Leu Arg Gln Gly Met Phe Ala Gln Leu Val Ala 
        35                  40                  45              


Gln Asn Val Leu Leu Ile Asp Gly Pro Leu Ser Trp Tyr Ser Asp Pro 
    50                  55                  60                  


Gly Leu Ala Gly Val Ser Leu Thr Gly Gly Leu Ser Tyr Lys Glu Asp 
65                  70                  75                  80  


Thr Lys Glu Leu Val Val Ala Lys Ala Gly Val Tyr Tyr Val Phe Phe 
                85                  90                  95      


Gln Leu Glu Leu Arg Arg Val Val Ala Gly Glu Gly Ser Gly Ser Val 
            100                 105                 110         


Ser Leu Ala Leu His Leu Gln Pro Leu Arg Ser Ala Ala Gly Ala Ala 
        115                 120                 125             


Ala Leu Ala Leu Thr Val Asp Leu Pro Pro Ala Ser Ser Glu Ala Arg 
    130                 135                 140                 


Asn Ser Ala Phe Gly Phe Gln Gly Arg Leu Leu His Leu Ser Ala Gly 
145                 150                 155                 160 


Gln Arg Leu Gly Val His Leu His Thr Glu Ala Arg Ala Arg His Ala 
                165                 170                 175     


Trp Gln Leu Thr Gln Gly Ala Thr Val Leu Gly Leu Phe Arg Val Thr 
            180                 185                 190         


Pro Glu Ile Pro Ala Gly Leu Pro Ser Pro Arg Ser Glu 
        195                 200                 205 


<210>  1322
<211>  1271
<212>  PRT
<213>  Homo Sapiens

<400>  1322

Glu Pro Pro Gly Cys Ser Asn Lys Glu Gln Gln Val Thr Val Ser His 
1               5                   10                  15      


Thr Tyr Lys Ile Asp Val Pro Lys Ser Ala Leu Val Gln Val Asp Ala 
            20                  25                  30          


Asp Pro Gln Pro Leu Ser Asp Asp Gly Ala Ser Leu Leu Ala Leu Gly 
        35                  40                  45              


Glu Ala Arg Glu Glu Gln Asn Ile Ile Phe Arg His Asn Ile Arg Leu 
    50                  55                  60                  


Gln Thr Pro Gln Lys Asp Cys Glu Leu Ala Gly Ser Val Gln Asp Leu 
65                  70                  75                  80  


Leu Ala Arg Val Lys Lys Leu Glu Glu Glu Met Val Glu Met Lys Glu 
                85                  90                  95      


Gln Cys Ser Ala Gln Arg Cys Cys Gln Gly Val Thr Asp Leu Ser Arg 
            100                 105                 110         


His Cys Ser Gly His Gly Thr Phe Ser Leu Glu Thr Cys Ser Cys His 
        115                 120                 125             


Cys Glu Glu Gly Arg Glu Gly Pro Ala Cys Glu Arg Leu Ala Cys Pro 
    130                 135                 140                 


Gly Ala Cys Ser Gly His Gly Arg Cys Val Asp Gly Arg Cys Leu Cys 
145                 150                 155                 160 


His Glu Pro Tyr Val Gly Ala Asp Cys Gly Tyr Pro Ala Cys Pro Glu 
                165                 170                 175     


Asn Cys Ser Gly His Gly Glu Cys Val Arg Gly Val Cys Gln Cys His 
            180                 185                 190         


Glu Asp Phe Met Ser Glu Asp Cys Ser Glu Lys Arg Cys Pro Gly Asp 
        195                 200                 205             


Cys Ser Gly His Gly Phe Cys Asp Thr Gly Glu Cys Tyr Cys Glu Glu 
    210                 215                 220                 


Gly Phe Thr Gly Leu Asp Cys Ala Gln Val Val Thr Pro Gln Gly Leu 
225                 230                 235                 240 


Gln Leu Leu Lys Asn Thr Glu Asp Ser Leu Leu Val Ser Trp Glu Pro 
                245                 250                 255     


Ser Ser Gln Val Asp His Tyr Leu Leu Ser Tyr Tyr Pro Leu Gly Lys 
            260                 265                 270         


Glu Leu Ser Gly Lys Gln Ile Gln Val Pro Lys Glu Gln His Ser Tyr 
        275                 280                 285             


Glu Ile Leu Gly Leu Leu Pro Gly Thr Lys Tyr Ile Val Thr Leu Arg 
    290                 295                 300                 


Asn Val Lys Asn Glu Val Ser Ser Ser Pro Gln His Leu Leu Ala Thr 
305                 310                 315                 320 


Thr Asp Leu Ala Val Leu Gly Thr Ala Trp Val Thr Asp Glu Thr Glu 
                325                 330                 335     


Asn Ser Leu Asp Val Glu Trp Glu Asn Pro Ser Thr Glu Val Asp Tyr 
            340                 345                 350         


Tyr Lys Leu Arg Tyr Gly Pro Met Thr Gly Gln Glu Val Ala Glu Val 
        355                 360                 365             


Thr Val Pro Lys Ser Ser Asp Pro Lys Ser Arg Tyr Asp Ile Thr Gly 
    370                 375                 380                 


Leu His Pro Gly Thr Glu Tyr Lys Ile Thr Val Val Pro Met Arg Gly 
385                 390                 395                 400 


Glu Leu Glu Gly Lys Pro Ile Leu Leu Asn Gly Arg Thr Glu Ile Asp 
                405                 410                 415     


Ser Pro Thr Asn Val Val Thr Asp Arg Val Thr Glu Asp Thr Ala Thr 
            420                 425                 430         


Val Ser Trp Asp Pro Val Gln Ala Val Ile Asp Lys Tyr Val Val Arg 
        435                 440                 445             


Tyr Thr Ser Ala Asp Gly Asp Thr Lys Glu Met Ala Val His Lys Asp 
    450                 455                 460                 


Glu Ser Ser Thr Val Leu Thr Gly Leu Lys Pro Gly Glu Ala Tyr Lys 
465                 470                 475                 480 


Val Tyr Val Trp Ala Glu Arg Gly Asn Gln Gly Ser Lys Lys Ala Asp 
                485                 490                 495     


Thr Asn Ala Leu Thr Glu Ile Asp Ser Pro Ala Asn Leu Val Thr Asp 
            500                 505                 510         


Arg Val Thr Glu Asn Thr Ala Thr Ile Ser Trp Asp Pro Val Gln Ala 
        515                 520                 525             


Thr Ile Asp Lys Tyr Val Val Arg Tyr Thr Ser Ala Asp Asp Gln Glu 
    530                 535                 540                 


Thr Arg Glu Val Leu Val Gly Lys Glu Gln Ser Ser Thr Val Leu Thr 
545                 550                 555                 560 


Gly Leu Arg Pro Gly Val Glu Tyr Thr Val His Val Trp Ala Gln Lys 
                565                 570                 575     


Gly Asp Arg Glu Ser Lys Lys Ala Asp Thr Asn Ala Pro Thr Asp Ile 
            580                 585                 590         


Asp Ser Pro Lys Asn Leu Val Thr Asp Arg Val Thr Glu Asn Met Ala 
        595                 600                 605             


Thr Val Ser Trp Asp Pro Val Gln Ala Ala Ile Asp Lys Tyr Val Val 
    610                 615                 620                 


Arg Tyr Thr Ser Ala Gly Gly Glu Thr Arg Glu Val Pro Val Gly Lys 
625                 630                 635                 640 


Glu Gln Ser Ser Thr Val Leu Thr Gly Leu Arg Pro Gly Met Glu Tyr 
                645                 650                 655     


Met Val His Val Trp Ala Gln Lys Gly Asp Gln Glu Ser Lys Lys Ala 
            660                 665                 670         


Asp Thr Lys Ala Gln Thr Asp Ile Asp Ser Pro Gln Asn Leu Val Thr 
        675                 680                 685             


Asp Arg Val Thr Glu Asn Met Ala Thr Val Ser Trp Asp Pro Val Arg 
    690                 695                 700                 


Ala Thr Ile Asp Arg Tyr Val Val Arg Tyr Thr Ser Ala Lys Asp Gly 
705                 710                 715                 720 


Glu Thr Arg Glu Val Pro Val Gly Lys Glu Gln Ser Ser Thr Val Leu 
                725                 730                 735     


Thr Gly Leu Arg Pro Gly Val Glu Tyr Thr Val His Val Trp Ala Gln 
            740                 745                 750         


Lys Gly Ala Gln Glu Ser Lys Lys Ala Asp Thr Lys Ala Gln Thr Asp 
        755                 760                 765             


Ile Asp Ser Pro Gln Asn Leu Val Thr Asp Trp Val Thr Glu Asn Thr 
    770                 775                 780                 


Ala Thr Val Ser Trp Asp Pro Val Gln Ala Thr Ile Asp Arg Tyr Val 
785                 790                 795                 800 


Val His Tyr Thr Ser Ala Asn Gly Glu Thr Arg Glu Val Pro Val Gly 
                805                 810                 815     


Lys Glu Gln Ser Ser Thr Val Leu Thr Gly Leu Arg Pro Gly Met Glu 
            820                 825                 830         


Tyr Thr Val His Val Trp Ala Gln Lys Gly Asn Gln Glu Ser Lys Lys 
        835                 840                 845             


Ala Asp Thr Lys Ala Gln Thr Glu Ile Asp Gly Pro Lys Asn Leu Val 
    850                 855                 860                 


Thr Asp Trp Val Thr Glu Asn Met Ala Thr Val Ser Trp Asp Pro Val 
865                 870                 875                 880 


Gln Ala Thr Ile Asp Lys Tyr Met Val Arg Tyr Thr Ser Ala Asp Gly 
                885                 890                 895     


Glu Thr Arg Glu Val Pro Val Gly Lys Glu His Ser Ser Thr Val Leu 
            900                 905                 910         


Thr Gly Leu Arg Pro Gly Met Glu Tyr Met Val His Val Trp Ala Gln 
        915                 920                 925             


Lys Gly Ala Gln Glu Ser Lys Lys Ala Asp Thr Lys Ala Gln Thr Glu 
    930                 935                 940                 


Leu Asp Pro Pro Arg Asn Leu Arg Pro Ser Ala Val Thr Gln Ser Gly 
945                 950                 955                 960 


Gly Ile Leu Thr Trp Thr Pro Pro Ser Ala Gln Ile His Gly Tyr Ile 
                965                 970                 975     


Leu Thr Tyr Gln Phe Pro Asp Gly Thr Val Lys Glu Met Gln Leu Gly 
            980                 985                 990         


Arg Glu Asp Gln Arg Phe Ala Leu  Gln Gly Leu Glu Gln  Gly Ala Thr 
        995                 1000                 1005             


Tyr Pro  Val Ser Leu Val Ala  Phe Lys Gly Gly Arg  Arg Ser Arg 
    1010                 1015                 1020             


Asn Val  Ser Thr Thr Leu Ser  Thr Val Gly Ala Arg  Phe Pro His 
    1025                 1030                 1035             


Pro Ser  Asp Cys Ser Gln Val  Gln Gln Asn Ser Asn  Ala Ala Ser 
    1040                 1045                 1050             


Gly Leu  Tyr Thr Ile Tyr Leu  His Gly Asp Ala Ser  Arg Pro Leu 
    1055                 1060                 1065             


Gln Val  Tyr Cys Asp Met Glu  Thr Asp Gly Gly Gly  Trp Ile Val 
    1070                 1075                 1080             


Phe Gln  Arg Arg Asn Thr Gly  Gln Leu Asp Phe Phe  Lys Arg Trp 
    1085                 1090                 1095             


Arg Ser  Tyr Val Glu Gly Phe  Gly Asp Pro Met Lys  Glu Phe Trp 
    1100                 1105                 1110             


Leu Gly  Leu Asp Lys Leu His  Asn Leu Thr Thr Gly  Thr Pro Ala 
    1115                 1120                 1125             


Arg Tyr  Glu Val Arg Val Asp  Leu Gln Thr Ala Asn  Glu Ser Ala 
    1130                 1135                 1140             


Tyr Ala  Ile Tyr Asp Phe Phe  Gln Val Ala Ser Ser  Lys Glu Arg 
    1145                 1150                 1155             


Tyr Lys  Leu Thr Val Gly Lys  Tyr Arg Gly Thr Ala  Gly Asp Ala 
    1160                 1165                 1170             


Leu Thr  Tyr His Asn Gly Trp  Lys Phe Thr Thr Phe  Asp Arg Asp 
    1175                 1180                 1185             


Asn Asp  Ile Ala Leu Ser Asn  Cys Ala Leu Thr His  His Gly Gly 
    1190                 1195                 1200             


Trp Trp  Tyr Lys Asn Cys His  Leu Ala Asn Pro Asn  Gly Arg Tyr 
    1205                 1210                 1215             


Gly Glu  Thr Lys His Ser Glu  Gly Val Asn Trp Glu  Pro Trp Lys 
    1220                 1225                 1230             


Gly His  Glu Phe Ser Ile Pro  Tyr Val Glu Leu Lys  Ile Arg Pro 
    1235                 1240                 1245             


His Gly  Tyr Ser Arg Glu Pro  Val Leu Gly Arg Lys  Lys Arg Thr 
    1250                 1255                 1260             


Leu Arg  Gly Arg Leu Arg Thr  Phe 
    1265                 1270     


<210>  1323
<211>  1171
<212>  PRT
<213>  Homo Sapiens

<400>  1323

Cys Ile Cys Asn Glu Gly Trp Phe Gly Lys Asn Cys Ser Glu Pro Tyr 
1               5                   10                  15      


Cys Pro Leu Gly Cys Ser Ser Arg Gly Val Cys Val Asp Gly Gln Cys 
            20                  25                  30          


Ile Cys Asp Ser Glu Tyr Ser Gly Asp Asp Cys Ser Glu Leu Arg Cys 
        35                  40                  45              


Pro Thr Asp Cys Ser Ser Arg Gly Leu Cys Val Asp Gly Glu Cys Val 
    50                  55                  60                  


Cys Glu Glu Pro Tyr Thr Gly Glu Asp Cys Arg Glu Leu Arg Cys Pro 
65                  70                  75                  80  


Gly Asp Cys Ser Gly Lys Gly Arg Cys Ala Asn Gly Thr Cys Leu Cys 
                85                  90                  95      


Glu Glu Gly Tyr Val Gly Glu Asp Cys Gly Gln Arg Gln Cys Leu Asn 
            100                 105                 110         


Ala Cys Ser Gly Arg Gly Gln Cys Glu Glu Gly Leu Cys Val Cys Glu 
        115                 120                 125             


Glu Gly Tyr Gln Gly Pro Asp Cys Ser Ala Val Ala Pro Pro Glu Asp 
    130                 135                 140                 


Leu Arg Val Ala Gly Ile Ser Asp Arg Ser Ile Glu Leu Glu Trp Asp 
145                 150                 155                 160 


Gly Pro Met Ala Val Thr Glu Tyr Val Ile Ser Tyr Gln Pro Thr Ala 
                165                 170                 175     


Leu Gly Gly Leu Gln Leu Gln Gln Arg Val Pro Gly Asp Trp Ser Gly 
            180                 185                 190         


Val Thr Ile Thr Glu Leu Glu Pro Gly Leu Thr Tyr Asn Ile Ser Val 
        195                 200                 205             


Tyr Ala Val Ile Ser Asn Ile Leu Ser Leu Pro Ile Thr Ala Lys Val 
    210                 215                 220                 


Ala Thr His Leu Ser Thr Pro Gln Gly Leu Gln Phe Lys Thr Ile Thr 
225                 230                 235                 240 


Glu Thr Thr Val Glu Val Gln Trp Glu Pro Phe Ser Phe Ser Phe Asp 
                245                 250                 255     


Gly Trp Glu Ile Ser Phe Ile Pro Lys Asn Asn Glu Gly Gly Val Ile 
            260                 265                 270         


Ala Gln Val Pro Ser Asp Val Thr Ser Phe Asn Gln Thr Gly Leu Lys 
        275                 280                 285             


Pro Gly Glu Glu Tyr Ile Val Asn Val Val Ala Leu Lys Glu Gln Ala 
    290                 295                 300                 


Arg Ser Pro Pro Thr Ser Ala Ser Val Ser Thr Val Ile Asp Gly Pro 
305                 310                 315                 320 


Thr Gln Ile Leu Val Arg Asp Val Ser Asp Thr Val Ala Phe Val Glu 
                325                 330                 335     


Trp Ile Pro Pro Arg Ala Lys Val Asp Phe Ile Leu Leu Lys Tyr Gly 
            340                 345                 350         


Leu Val Gly Gly Glu Gly Gly Arg Thr Thr Phe Arg Leu Gln Pro Pro 
        355                 360                 365             


Leu Ser Gln Tyr Ser Val Gln Ala Leu Arg Pro Gly Ser Arg Tyr Glu 
    370                 375                 380                 


Val Ser Val Ser Ala Val Arg Gly Thr Asn Glu Ser Asp Ser Ala Thr 
385                 390                 395                 400 


Thr Gln Phe Thr Thr Glu Ile Asp Ala Pro Lys Asn Leu Arg Val Gly 
                405                 410                 415     


Ser Arg Thr Ala Thr Ser Leu Asp Leu Glu Trp Asp Asn Ser Glu Ala 
            420                 425                 430         


Glu Val Gln Glu Tyr Lys Val Val Tyr Ser Thr Leu Ala Gly Glu Gln 
        435                 440                 445             


Tyr His Glu Val Leu Val Pro Arg Gly Ile Gly Pro Thr Thr Arg Ala 
    450                 455                 460                 


Thr Leu Thr Asp Leu Val Pro Gly Thr Glu Tyr Gly Val Gly Ile Ser 
465                 470                 475                 480 


Ala Val Met Asn Ser Gln Gln Ser Val Pro Ala Thr Met Asn Ala Arg 
                485                 490                 495     


Thr Glu Leu Asp Ser Pro Arg Asp Leu Met Val Thr Ala Ser Ser Glu 
            500                 505                 510         


Thr Ser Ile Ser Leu Ile Trp Thr Lys Ala Ser Gly Pro Ile Asp His 
        515                 520                 525             


Tyr Arg Ile Thr Phe Thr Pro Ser Ser Gly Ile Ala Ser Glu Val Thr 
    530                 535                 540                 


Val Pro Lys Asp Arg Thr Ser Tyr Thr Leu Thr Asp Leu Glu Pro Gly 
545                 550                 555                 560 


Ala Glu Tyr Ile Ile Ser Val Thr Ala Glu Arg Gly Arg Gln Gln Ser 
                565                 570                 575     


Leu Glu Ser Thr Val Asp Ala Phe Thr Gly Phe Arg Pro Ile Ser His 
            580                 585                 590         


Leu His Phe Ser His Val Thr Ser Ser Ser Val Asn Ile Thr Trp Ser 
        595                 600                 605             


Asp Pro Ser Pro Pro Ala Asp Arg Leu Ile Leu Asn Tyr Ser Pro Arg 
    610                 615                 620                 


Asp Glu Glu Glu Glu Met Met Glu Val Ser Leu Asp Ala Thr Lys Arg 
625                 630                 635                 640 


His Ala Val Leu Met Gly Leu Gln Pro Ala Thr Glu Tyr Ile Val Asn 
                645                 650                 655     


Leu Val Ala Val His Gly Thr Val Thr Ser Glu Pro Ile Val Gly Ser 
            660                 665                 670         


Ile Thr Thr Gly Ile Asp Pro Pro Lys Asp Ile Thr Ile Ser Asn Val 
        675                 680                 685             


Thr Lys Asp Ser Val Met Val Ser Trp Ser Pro Pro Val Ala Ser Phe 
    690                 695                 700                 


Asp Tyr Tyr Arg Val Ser Tyr Arg Pro Thr Gln Val Gly Arg Leu Asp 
705                 710                 715                 720 


Ser Ser Val Val Pro Asn Thr Val Thr Glu Phe Thr Ile Thr Arg Leu 
                725                 730                 735     


Asn Pro Ala Thr Glu Tyr Glu Ile Ser Leu Asn Ser Val Arg Gly Arg 
            740                 745                 750         


Glu Glu Ser Glu Arg Ile Cys Thr Leu Val His Thr Ala Met Asp Asn 
        755                 760                 765             


Pro Val Asp Leu Ile Ala Thr Asn Ile Thr Pro Thr Glu Ala Leu Leu 
    770                 775                 780                 


Gln Trp Lys Ala Pro Val Gly Glu Val Glu Asn Tyr Val Ile Val Leu 
785                 790                 795                 800 


Thr His Phe Ala Val Ala Gly Glu Thr Ile Leu Val Asp Gly Val Ser 
                805                 810                 815     


Glu Glu Phe Arg Leu Val Asp Leu Leu Pro Ser Thr His Tyr Thr Ala 
            820                 825                 830         


Thr Met Tyr Ala Thr Asn Gly Pro Leu Thr Ser Gly Thr Ile Ser Thr 
        835                 840                 845             


Asn Phe Ser Thr Leu Leu Asp Pro Pro Ala Asn Leu Thr Ala Ser Glu 
    850                 855                 860                 


Val Thr Arg Gln Ser Ala Leu Ile Ser Trp Gln Pro Pro Arg Ala Glu 
865                 870                 875                 880 


Ile Glu Asn Tyr Val Leu Thr Tyr Lys Ser Thr Asp Gly Ser Arg Lys 
                885                 890                 895     


Glu Leu Ile Val Asp Ala Glu Asp Thr Trp Ile Arg Leu Glu Gly Leu 
            900                 905                 910         


Leu Glu Asn Thr Asp Tyr Thr Val Leu Leu Gln Ala Ala Gln Asp Thr 
        915                 920                 925             


Thr Trp Ser Ser Ile Thr Ser Thr Ala Phe Thr Thr Gly Gly Arg Val 
    930                 935                 940                 


Phe Pro His Pro Gln Asp Cys Ala Gln His Leu Met Asn Gly Asp Thr 
945                 950                 955                 960 


Leu Ser Gly Val Tyr Pro Ile Phe Leu Asn Gly Glu Leu Ser Gln Lys 
                965                 970                 975     


Leu Gln Val Tyr Cys Asp Met Thr Thr Asp Gly Gly Gly Trp Ile Val 
            980                 985                 990         


Phe Gln Arg Arg Gln Asn Gly Gln  Thr Asp Phe Phe Arg  Lys Trp Ala 
        995                 1000                 1005             


Asp Tyr  Arg Val Gly Phe Gly  Asn Val Glu Asp Glu  Phe Trp Leu 
    1010                 1015                 1020             


Gly Leu  Asp Asn Ile His Arg  Ile Thr Ser Gln Gly  Arg Tyr Glu 
    1025                 1030                 1035             


Leu Arg  Val Asp Met Arg Asp  Gly Gln Glu Ala Ala  Phe Ala Ser 
    1040                 1045                 1050             


Tyr Asp  Arg Phe Ser Val Glu  Asp Ser Arg Asn Leu  Tyr Lys Leu 
    1055                 1060                 1065             


Arg Ile  Gly Ser Tyr Asn Gly  Thr Ala Gly Asp Ser  Leu Ser Tyr 
    1070                 1075                 1080             


His Gln  Gly Arg Pro Phe Ser  Thr Glu Asp Arg Asp  Asn Asp Val 
    1085                 1090                 1095             


Ala Val  Thr Asn Cys Ala Met  Ser Tyr Lys Gly Ala  Trp Trp Tyr 
    1100                 1105                 1110             


Lys Asn  Cys His Arg Thr Asn  Leu Asn Gly Lys Tyr  Gly Glu Ser 
    1115                 1120                 1125             


Arg His  Ser Gln Gly Ile Asn  Trp Tyr His Trp Lys  Gly His Glu 
    1130                 1135                 1140             


Phe Ser  Ile Pro Phe Val Glu  Met Lys Met Arg Pro  Tyr Asn His 
    1145                 1150                 1155             


Arg Leu  Met Ala Gly Arg Lys  Arg Gln Ser Leu Gln  Phe 
    1160                 1165                 1170     


<210>  1324
<211>  794
<212>  PRT
<213>  Homo Sapiens

<400>  1324

His Leu Gly Glu Leu Thr Val Ala Glu Glu Thr Ser Ser Ser Leu Arg 
1               5                   10                  15      


Leu Ser Trp Thr Val Ala Gln Gly Pro Phe Asp Ser Phe Val Val Gln 
            20                  25                  30          


Tyr Arg Asp Thr Asp Gly Gln Pro Arg Ala Val Pro Val Ala Ala Asp 
        35                  40                  45              


Gln Arg Thr Val Thr Val Glu Asp Leu Glu Pro Gly Lys Lys Tyr Lys 
    50                  55                  60                  


Phe Leu Leu Tyr Gly Leu Leu Gly Gly Lys Arg Leu Gly Pro Val Ser 
65                  70                  75                  80  


Ala Leu Gly Met Thr Ala Pro Glu Glu Asp Thr Pro Ala Pro Glu Leu 
                85                  90                  95      


Ala Pro Glu Ala Pro Glu Pro Pro Glu Glu Pro Arg Leu Gly Val Leu 
            100                 105                 110         


Thr Val Thr Asp Thr Thr Pro Asp Ser Met Arg Leu Ser Trp Ser Val 
        115                 120                 125             


Ala Gln Gly Pro Phe Asp Ser Phe Val Val Gln Tyr Glu Asp Thr Asn 
    130                 135                 140                 


Gly Gln Pro Gln Ala Leu Leu Val Asp Gly Asp Gln Ser Lys Ile Leu 
145                 150                 155                 160 


Ile Ser Gly Leu Glu Pro Ser Thr Pro Tyr Arg Phe Leu Leu Tyr Gly 
                165                 170                 175     


Leu His Glu Gly Lys Arg Leu Gly Pro Leu Ser Ala Glu Gly Thr Thr 
            180                 185                 190         


Gly Leu Ala Pro Ala Gly Gln Thr Ser Glu Glu Ser Arg Pro Arg Leu 
        195                 200                 205             


Ser Gln Leu Ser Val Thr Asp Val Thr Thr Ser Ser Leu Arg Leu Asn 
    210                 215                 220                 


Trp Glu Ala Pro Pro Gly Ala Phe Asp Ser Phe Leu Leu Arg Phe Gly 
225                 230                 235                 240 


Val Pro Ser Pro Ser Thr Leu Glu Pro His Pro Arg Pro Leu Leu Gln 
                245                 250                 255     


Arg Glu Leu Met Val Pro Gly Thr Arg His Ser Ala Val Leu Arg Asp 
            260                 265                 270         


Leu Arg Ser Gly Thr Leu Tyr Ser Leu Thr Leu Tyr Gly Leu Arg Gly 
        275                 280                 285             


Pro His Lys Ala Asp Ser Ile Gln Gly Thr Ala Arg Thr Leu Ser Pro 
    290                 295                 300                 


Val Leu Glu Ser Pro Arg Asp Leu Gln Phe Ser Glu Ile Arg Glu Thr 
305                 310                 315                 320 


Ser Ala Lys Val Asn Trp Met Pro Pro Pro Ser Arg Ala Asp Ser Phe 
                325                 330                 335     


Lys Val Ser Tyr Leu Leu Ala Asp Gly Gly Glu Pro Gln Ser Val Gln 
            340                 345                 350         


Val Asp Gly Gln Ala Arg Thr Gln Lys Leu Gln Gly Leu Ile Pro Gly 
        355                 360                 365             


Ala Arg Tyr Glu Val Thr Val Val Ser Val Arg Gly Phe Glu Glu Ser 
    370                 375                 380                 


Glu Pro Leu Thr Gly Phe Leu Thr Thr Val Pro Asp Gly Pro Thr Gln 
385                 390                 395                 400 


Leu Arg Ala Leu Asn Leu Thr Glu Gly Phe Ala Val Leu His Trp Lys 
                405                 410                 415     


Pro Pro Gln Asn Pro Val Asp Thr Tyr Asp Val Gln Val Thr Ala Pro 
            420                 425                 430         


Gly Ala Pro Pro Leu Gln Ala Glu Thr Pro Gly Ser Ala Val Asp Tyr 
        435                 440                 445             


Pro Leu His Asp Leu Val Leu His Thr Asn Tyr Thr Ala Thr Val Arg 
    450                 455                 460                 


Gly Leu Arg Gly Pro Asn Leu Thr Ser Pro Ala Ser Ile Thr Phe Thr 
465                 470                 475                 480 


Thr Gly Leu Glu Ala Pro Arg Asp Leu Glu Ala Lys Glu Val Thr Pro 
                485                 490                 495     


Arg Thr Ala Leu Leu Thr Trp Thr Glu Pro Pro Val Arg Pro Ala Gly 
            500                 505                 510         


Tyr Leu Leu Ser Phe His Thr Pro Gly Gly Gln Asn Gln Glu Ile Leu 
        515                 520                 525             


Leu Pro Gly Gly Ile Thr Ser His Gln Leu Leu Gly Leu Phe Pro Ser 
    530                 535                 540                 


Thr Ser Tyr Asn Ala Arg Leu Gln Ala Met Trp Gly Gln Ser Leu Leu 
545                 550                 555                 560 


Pro Pro Val Ser Thr Ser Phe Thr Thr Gly Gly Leu Arg Ile Pro Phe 
                565                 570                 575     


Pro Arg Asp Cys Gly Glu Glu Met Gln Asn Gly Ala Gly Ala Ser Arg 
            580                 585                 590         


Thr Ser Thr Ile Phe Leu Asn Gly Asn Arg Glu Arg Pro Leu Asn Val 
        595                 600                 605             


Phe Cys Asp Met Glu Thr Asp Gly Gly Gly Trp Leu Val Phe Gln Arg 
    610                 615                 620                 


Arg Met Asp Gly Gln Thr Asp Phe Trp Arg Asp Trp Glu Asp Tyr Ala 
625                 630                 635                 640 


His Gly Phe Gly Asn Ile Ser Gly Glu Phe Trp Leu Gly Asn Glu Ala 
                645                 650                 655     


Leu His Ser Leu Thr Gln Ala Gly Asp Tyr Ser Met Arg Val Asp Leu 
            660                 665                 670         


Arg Ala Gly Asp Glu Ala Val Phe Ala Gln Tyr Asp Ser Phe His Val 
        675                 680                 685             


Asp Ser Ala Ala Glu Tyr Tyr Arg Leu His Leu Glu Gly Tyr His Gly 
    690                 695                 700                 


Thr Ala Gly Asp Ser Met Ser Tyr His Ser Gly Ser Val Phe Ser Ala 
705                 710                 715                 720 


Arg Asp Arg Asp Pro Asn Ser Leu Leu Ile Ser Cys Ala Val Ser Tyr 
                725                 730                 735     


Arg Gly Ala Trp Trp Tyr Arg Asn Cys His Tyr Ala Asn Leu Asn Gly 
            740                 745                 750         


Leu Tyr Gly Ser Thr Val Asp His Gln Gly Val Ser Trp Tyr His Trp 
        755                 760                 765             


Lys Gly Phe Glu Phe Ser Val Pro Phe Thr Glu Met Lys Leu Arg Pro 
    770                 775                 780                 


Arg Asn Phe Arg Ser Pro Ala Gly Gly Gly 
785                 790                 


<210>  1325
<211>  324
<212>  PRT
<213>  Homo Sapiens

<400>  1325

Ser Ser Pro Thr Ser Ser Ala Ser Ser Phe Ser Ser Ser Ala Pro Phe 
1               5                   10                  15      


Leu Ala Ser Ala Val Ser Ala Gln Pro Pro Leu Pro Asp Gln Cys Pro 
            20                  25                  30          


Ala Leu Cys Glu Cys Ser Glu Ala Ala Arg Thr Val Lys Cys Val Asn 
        35                  40                  45              


Arg Asn Leu Thr Glu Val Pro Thr Asp Leu Pro Ala Tyr Val Arg Asn 
    50                  55                  60                  


Leu Phe Leu Thr Gly Asn Gln Leu Ala Val Leu Pro Ala Gly Ala Phe 
65                  70                  75                  80  


Ala Arg Arg Pro Pro Leu Ala Glu Leu Ala Ala Leu Asn Leu Ser Gly 
                85                  90                  95      


Ser Arg Leu Asp Glu Val Arg Ala Gly Ala Phe Glu His Leu Pro Ser 
            100                 105                 110         


Leu Arg Gln Leu Asp Leu Ser His Asn Pro Leu Ala Asp Leu Ser Pro 
        115                 120                 125             


Phe Ala Phe Ser Gly Ser Asn Ala Ser Val Ser Ala Pro Ser Pro Leu 
    130                 135                 140                 


Val Glu Leu Ile Leu Asn His Ile Val Pro Pro Glu Asp Glu Arg Gln 
145                 150                 155                 160 


Asn Arg Ser Phe Glu Gly Met Val Val Ala Ala Leu Leu Ala Gly Arg 
                165                 170                 175     


Ala Leu Gln Gly Leu Arg Arg Leu Glu Leu Ala Ser Asn His Phe Leu 
            180                 185                 190         


Tyr Leu Pro Arg Asp Val Leu Ala Gln Leu Pro Ser Leu Arg His Leu 
        195                 200                 205             


Asp Leu Ser Asn Asn Ser Leu Val Ser Leu Thr Tyr Val Ser Phe Arg 
    210                 215                 220                 


Asn Leu Thr His Leu Glu Ser Leu His Leu Glu Asp Asn Ala Leu Lys 
225                 230                 235                 240 


Val Leu His Asn Gly Thr Leu Ala Glu Leu Gln Gly Leu Pro His Ile 
                245                 250                 255     


Arg Val Phe Leu Asp Asn Asn Pro Trp Val Cys Asp Cys His Met Ala 
            260                 265                 270         


Asp Met Val Thr Trp Leu Lys Glu Thr Glu Val Val Gln Gly Lys Asp 
        275                 280                 285             


Arg Leu Thr Cys Ala Tyr Pro Glu Lys Met Arg Asn Arg Val Leu Leu 
    290                 295                 300                 


Glu Leu Asn Ser Ala Asp Leu Asp Cys Asp Pro Ile Leu Pro Pro Ser 
305                 310                 315                 320 


Leu Gln Thr Ser 
                


<210>  1326
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  1326

Cys Pro Phe Gln Cys Tyr Cys Phe Gly Gly Pro Lys Leu Leu Leu Arg 
1               5                   10                  15      


Cys Ala Ser Gly Ala Glu Leu Arg Gln Pro Pro Arg Asp Val Pro Pro 
            20                  25                  30          


Asp Ala Arg Asn Leu Thr Ile Val Gly Ala Asn Leu Thr Val Leu Arg 
        35                  40                  45              


Ala Ala Ala Phe Ala Gly Gly Asp Gly Asp Gly Asp Gln Ala Ala Gly 
    50                  55                  60                  


Val Arg Leu Pro Leu Leu Ser Ala Leu Arg Leu Thr His Asn His Ile 
65                  70                  75                  80  


Glu Val Val Glu Asp Gly Ala Phe Asp Gly Leu Pro Ser Leu Ala Ala 
                85                  90                  95      


Leu Asp Leu Ser His Asn Pro Leu Arg Ala Leu Gly Gly Gly Ala Phe 
            100                 105                 110         


Arg Gly Leu Pro Ala Leu Arg Ser Leu Gln Leu Asn His Ala Leu Val 
        115                 120                 125             


Arg Gly Gly Pro Ala Leu Leu Ala Ala Leu Asp Ala Ala Leu Ala Pro 
    130                 135                 140                 


Leu Ala Glu Leu Arg Leu Leu Gly Leu Ala Gly Asn Ala Leu Ser Arg 
145                 150                 155                 160 


Leu Pro Pro Ala Ala Leu Arg Leu Ala Arg Leu Glu Gln Leu Asp Val 
                165                 170                 175     


Arg Leu Asn Ala Leu Ala Gly Leu Asp Pro Asp Glu Leu Arg Ala Leu 
            180                 185                 190         


Glu Arg Asp Gly Gly Leu Pro Gly Pro Arg Leu Leu Leu Ala Asp Asn 
        195                 200                 205             


Pro Leu Arg Cys Gly Cys Ala Ala Arg Pro Leu Leu Ala Trp Leu Arg 
    210                 215                 220                 


Asn Ala Thr Glu Arg Val Pro Asp Ser Arg Arg Leu Arg Cys Ala Ala 
225                 230                 235                 240 


Pro Arg Ala Leu Leu Asp Arg Pro Leu Leu Asp Leu Asp Gly Ala Arg 
                245                 250                 255     


Leu Arg Cys Ala Asp Ser Gly Ala Asp Ala Arg Gly Glu Glu Ala Glu 
            260                 265                 270         


Ala Ala Gly Pro Glu Leu Glu Ala Ser 
        275                 280     


<210>  1327
<211>  828
<212>  PRT
<213>  Homo Sapiens

<400>  1327

Phe Phe Pro Phe Ile Ser Arg Gly Lys Glu Leu Leu Trp Gly Lys Pro 
1               5                   10                  15      


Glu Glu Ser Arg Val Ser Ser Val Leu Glu Glu Ser Lys Arg Leu Val 
            20                  25                  30          


Asp Thr Ala Met Tyr Ala Thr Met Gln Arg Asn Leu Lys Lys Arg Gly 
        35                  40                  45              


Ile Leu Ser Ala Ala Gln Leu Leu Ser Phe Ser Lys Leu Pro Glu Pro 
    50                  55                  60                  


Thr Ser Gly Val Ile Ala Arg Ala Ala Glu Ile Met Glu Thr Ser Ile 
65                  70                  75                  80  


Gln Ala Met Lys Arg Lys Val Asn Leu Lys Thr Gln Gln Ser Gln His 
                85                  90                  95      


Pro Thr Asp Ala Leu Ser Glu Asp Leu Leu Ser Ile Ile Ala Asn Met 
            100                 105                 110         


Ser Gly Cys Leu Pro Tyr Met Leu Pro Pro Lys Cys Pro Asn Thr Cys 
        115                 120                 125             


Leu Ala Asn Lys Tyr Arg Pro Ile Thr Gly Ala Cys Asn Asn Arg Asp 
    130                 135                 140                 


His Pro Arg Trp Gly Ala Ser Asn Thr Ala Leu Ala Arg Trp Leu Pro 
145                 150                 155                 160 


Pro Val Tyr Glu Asp Gly Phe Ser Gln Pro Arg Gly Trp Asn Pro Gly 
                165                 170                 175     


Phe Leu Tyr Asn Gly Phe Pro Leu Pro Pro Val Arg Glu Val Thr Arg 
            180                 185                 190         


His Val Ile Gln Val Ser Asn Glu Val Val Thr Asp Asp Asp Arg Tyr 
        195                 200                 205             


Ser Asp Leu Leu Met Ala Trp Gly Gln Tyr Ile Asp His Asp Ile Ala 
    210                 215                 220                 


Phe Thr Pro Gln Ser Thr Ser Lys Ala Ala Phe Gly Gly Gly Ala Asp 
225                 230                 235                 240 


Cys Gln Met Thr Cys Glu Asn Gln Asn Pro Cys Phe Pro Ile Gln Leu 
                245                 250                 255     


Pro Glu Glu Ala Arg Pro Ala Ala Gly Thr Ala Cys Leu Pro Phe Tyr 
            260                 265                 270         


Arg Ser Ser Ala Ala Cys Gly Thr Gly Asp Gln Gly Ala Leu Phe Gly 
        275                 280                 285             


Asn Leu Ser Thr Ala Asn Pro Arg Gln Gln Met Asn Gly Leu Thr Ser 
    290                 295                 300                 


Phe Leu Asp Ala Ser Thr Val Tyr Gly Ser Ser Pro Ala Leu Glu Arg 
305                 310                 315                 320 


Gln Leu Arg Asn Trp Thr Ser Ala Glu Gly Leu Leu Arg Val His Ala 
                325                 330                 335     


Arg Leu Arg Asp Ser Gly Arg Ala Tyr Leu Pro Phe Val Pro Pro Arg 
            340                 345                 350         


Ala Pro Ala Ala Cys Ala Pro Glu Pro Gly Ile Pro Gly Glu Thr Arg 
        355                 360                 365             


Gly Pro Cys Phe Leu Ala Gly Asp Gly Arg Ala Ser Glu Val Pro Ser 
    370                 375                 380                 


Leu Thr Ala Leu His Thr Leu Trp Leu Arg Glu His Asn Arg Leu Ala 
385                 390                 395                 400 


Ala Ala Leu Lys Ala Leu Asn Ala His Trp Ser Ala Asp Ala Val Tyr 
                405                 410                 415     


Gln Glu Ala Arg Lys Val Val Gly Ala Leu His Gln Ile Ile Thr Leu 
            420                 425                 430         


Arg Asp Tyr Ile Pro Arg Ile Leu Gly Pro Glu Ala Phe Gln Gln Tyr 
        435                 440                 445             


Val Gly Pro Tyr Glu Gly Tyr Asp Ser Thr Ala Asn Pro Thr Val Ser 
    450                 455                 460                 


Asn Val Phe Ser Thr Ala Ala Phe Arg Phe Gly His Ala Thr Ile His 
465                 470                 475                 480 


Pro Leu Val Arg Arg Leu Asp Ala Ser Phe Gln Glu His Pro Asp Leu 
                485                 490                 495     


Pro Gly Leu Trp Leu His Gln Ala Phe Phe Ser Pro Trp Thr Leu Leu 
            500                 505                 510         


Arg Gly Gly Gly Leu Asp Pro Leu Ile Arg Gly Leu Leu Ala Arg Pro 
        515                 520                 525             


Ala Lys Leu Gln Val Gln Asp Gln Leu Met Asn Glu Glu Leu Thr Glu 
    530                 535                 540                 


Arg Leu Phe Val Leu Ser Asn Ser Ser Thr Leu Asp Leu Ala Ser Ile 
545                 550                 555                 560 


Asn Leu Gln Arg Gly Arg Asp His Gly Leu Pro Gly Tyr Asn Glu Trp 
                565                 570                 575     


Arg Glu Phe Cys Gly Leu Pro Arg Leu Glu Thr Pro Ala Asp Leu Ser 
            580                 585                 590         


Thr Ala Ile Ala Ser Arg Ser Val Ala Asp Lys Ile Leu Asp Leu Tyr 
        595                 600                 605             


Lys His Pro Asp Asn Ile Asp Val Trp Leu Gly Gly Leu Ala Glu Asn 
    610                 615                 620                 


Phe Leu Pro Arg Ala Arg Thr Gly Pro Leu Phe Ala Cys Leu Ile Gly 
625                 630                 635                 640 


Lys Gln Met Lys Ala Leu Arg Asp Gly Asp Trp Phe Trp Trp Glu Asn 
                645                 650                 655     


Ser His Val Phe Thr Asp Ala Gln Arg Arg Glu Leu Glu Lys His Ser 
            660                 665                 670         


Leu Ser Arg Val Ile Cys Asp Asn Thr Gly Leu Thr Arg Val Pro Met 
        675                 680                 685             


Asp Ala Phe Gln Val Gly Lys Phe Pro Glu Asp Phe Glu Ser Cys Asp 
    690                 695                 700                 


Ser Ile Thr Gly Met Asn Leu Glu Ala Trp Arg Glu Thr Phe Pro Gln 
705                 710                 715                 720 


Asp Asp Lys Cys Gly Phe Pro Glu Ser Val Glu Asn Gly Asp Phe Val 
                725                 730                 735     


His Cys Glu Glu Ser Gly Arg Arg Val Leu Val Tyr Ser Cys Arg His 
            740                 745                 750         


Gly Tyr Glu Leu Gln Gly Arg Glu Gln Leu Thr Cys Thr Gln Glu Gly 
        755                 760                 765             


Trp Asp Phe Gln Pro Pro Leu Cys Lys Asp Val Asn Glu Cys Ala Asp 
    770                 775                 780                 


Gly Ala His Pro Pro Cys His Ala Ser Ala Arg Cys Arg Asn Thr Lys 
785                 790                 795                 800 


Gly Gly Phe Gln Cys Leu Cys Ala Asp Pro Tyr Glu Leu Gly Asp Asp 
                805                 810                 815     


Gly Arg Thr Cys Val Asp Ser Gly Arg Leu Pro Arg 
            820                 825             


<210>  1328
<211>  458
<212>  PRT
<213>  Homo Sapiens

<400>  1328

Ala Ser Arg Arg Gly Ala Pro Gly Thr Ala Asn Cys Glu Leu Lys Pro 
1               5                   10                  15      


Gln Gln Ser Glu Leu Asn Ser Phe Leu Trp Thr Ile Lys Arg Asp Pro 
            20                  25                  30          


Pro Ser Tyr Phe Phe Gly Thr Ile His Val Pro Tyr Thr Arg Val Trp 
        35                  40                  45              


Asp Phe Ile Pro Asp Asn Ser Lys Glu Ala Phe Leu Gln Ser Ser Ile 
    50                  55                  60                  


Val Tyr Phe Glu Leu Asp Leu Thr Asp Pro Tyr Thr Ile Ser Ala Leu 
65                  70                  75                  80  


Thr Ser Cys Gln Met Leu Pro Gln Gly Glu Asn Leu Gln Asp Val Leu 
                85                  90                  95      


Pro Arg Asp Ile Tyr Cys Arg Leu Lys Arg His Leu Glu Tyr Val Lys 
            100                 105                 110         


Leu Met Met Pro Leu Trp Met Thr Pro Asp Gln Arg Gly Lys Gly Leu 
        115                 120                 125             


Tyr Ala Asp Tyr Leu Phe Asn Ala Ile Ala Gly Asn Trp Glu Arg Lys 
    130                 135                 140                 


Arg Pro Val Trp Val Met Leu Met Val Asn Ser Leu Thr Glu Val Asp 
145                 150                 155                 160 


Ile Lys Ser Arg Gly Val Pro Val Leu Asp Leu Phe Leu Ala Gln Glu 
                165                 170                 175     


Ala Glu Arg Leu Arg Lys Gln Thr Gly Ala Val Glu Lys Val Glu Glu 
            180                 185                 190         


Gln Cys His Pro Leu Asn Gly Leu Asn Phe Ser Gln Val Ile Phe Ala 
        195                 200                 205             


Leu Asn Gln Thr Leu Leu Gln Gln Glu Ser Leu Arg Ala Gly Ser Leu 
    210                 215                 220                 


Gln Ile Pro Tyr Thr Thr Glu Asp Leu Ile Lys His Tyr Asn Cys Gly 
225                 230                 235                 240 


Asp Leu Ser Ser Val Ile Leu Ser His Asp Ser Ser Gln Val Pro Asn 
                245                 250                 255     


Phe Ile Asn Ala Thr Leu Pro Pro Gln Glu Arg Ile Thr Ala Gln Glu 
            260                 265                 270         


Ile Asp Ser Tyr Leu Arg Arg Glu Leu Ile Tyr Lys Arg Asn Glu Arg 
        275                 280                 285             


Ile Gly Lys Arg Val Lys Ala Leu Leu Glu Glu Phe Pro Asp Lys Gly 
    290                 295                 300                 


Phe Phe Phe Ala Phe Gly Ala Gly His Phe Met Gly Asn Asn Thr Val 
305                 310                 315                 320 


Leu Asp Val Leu Arg Arg Glu Gly Tyr Glu Val Glu His Ala Pro Ala 
                325                 330                 335     


Gly Arg Pro Ile His Lys Gly Lys Ser Lys Lys Thr Ser Thr Arg Pro 
            340                 345                 350         


Thr Leu Ser Thr Ile Phe Ala Pro Lys Val Pro Thr Leu Glu Val Pro 
        355                 360                 365             


Ala Pro Glu Ala Val Ser Ser Gly His Ser Thr Leu Pro Pro Leu Val 
    370                 375                 380                 


Ser Arg Pro Gly Ser Ala Asp Thr Pro Ser Glu Ala Glu Gln Arg Phe 
385                 390                 395                 400 


Arg Lys Lys Arg Arg Arg Ser Gln Arg Arg Pro Arg Leu Arg Gln Phe 
                405                 410                 415     


Ser Asp Leu Trp Val Arg Leu Glu Glu Ser Asp Ile Val Pro Gln Leu 
            420                 425                 430         


Gln Val Pro Val Leu Asp Arg His Ile Ser Thr Glu Leu Arg Leu Pro 
        435                 440                 445             


Arg Arg Gly His Ser His His Ser Gln Met 
    450                 455             


<210>  1329
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  1329

Ala Thr Lys Leu Thr Glu Glu Lys Tyr Glu Leu Lys Glu Gly Gln Thr 
1               5                   10                  15      


Leu Asp Val Lys Cys Asp Tyr Thr Leu Glu Lys Phe Ala Ser Ser Gln 
            20                  25                  30          


Lys Ala Trp Gln Ile Ile Arg Asp Gly Glu Met Pro Lys Thr Leu Ala 
        35                  40                  45              


Cys Thr Glu Arg Pro Ser Lys Asn Ser His Pro Val Gln Val Gly Arg 
    50                  55                  60                  


Ile Ile Leu Glu Asp Tyr His Asp His Gly Leu Leu Arg Val Arg Met 
65                  70                  75                  80  


Val Asn Leu Gln Val Glu Asp Ser Gly Leu Tyr Gln Cys Val Ile Tyr 
                85                  90                  95      


Gln Pro Pro Lys Glu Pro His Met Leu Phe Asp Arg Ile Arg Leu Val 
            100                 105                 110         


Val Thr Lys Gly Phe Ser Gly Thr Pro Gly Ser Asn Glu Asn Ser Thr 
        115                 120                 125             


Gln Asn Val Tyr Lys Ile Pro Pro Thr Thr Thr Lys Ala Leu Cys Pro 
    130                 135                 140                 


Leu Tyr Thr Ser Pro Arg Thr Val Thr Gln Ala Pro Pro Lys Ser Thr 
145                 150                 155                 160 


Ala Asp Val Ser Thr Pro Asp Ser Glu Ile Asn Leu Thr Asn Val Thr 
                165                 170                 175     


Asp Ile Ile Arg Val Pro Val Phe Asn 
            180                 185 


<210>  1330
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  1330

His Asn Thr Thr Val Phe Gln Gly Val Ala Gly Gln Ser Leu Gln Val 
1               5                   10                  15      


Ser Cys Pro Tyr Asp Ser Met Lys His Trp Gly Arg Arg Lys Ala Trp 
            20                  25                  30          


Cys Arg Gln Leu Gly Glu Lys Gly Pro Cys Gln Arg Val Val Ser Thr 
        35                  40                  45              


His Asn Leu Trp Leu Leu Ser Phe Leu Arg Arg Trp Asn Gly Ser Thr 
    50                  55                  60                  


Ala Ile Thr Asp Asp Thr Leu Gly Gly Thr Leu Thr Ile Thr Leu Arg 
65                  70                  75                  80  


Asn Leu Gln Pro His Asp Ala Gly Leu Tyr Gln Cys Gln Ser Leu His 
                85                  90                  95      


Gly Ser Glu Ala Asp Thr Leu Arg Lys Val Leu Val Glu Val Leu Ala 
            100                 105                 110         


Asp Pro Leu Asp His Arg Asp Ala Gly Asp Leu Trp Phe Pro Gly Glu 
        115                 120                 125             


Ser Glu Ser Phe Glu Asp Ala His Val Glu His Ser Ile Ser Arg Pro 
    130                 135                 140                 


Ser Gln Gly Ser His Leu Pro Ser Cys Leu Ser Lys Glu Pro Leu Gly 
145                 150                 155                 160 


Arg Arg Asn Pro Leu Pro Thr His Phe His Pro Ser Pro Pro Gly Leu 
                165                 170                 175     


His Leu Ser His Gln Asp Ser Ser Ser Gln Arg Pro Leu Gly Cys Ser 
            180                 185                 190         


Leu Ala Trp Thr Glu Ala Arg Asp Thr Ser Thr Gln 
        195                 200                 


<210>  1331
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  1331

Gln Gly Ile Val Gly Ser Leu Pro Glu Val Leu Gln Ala Pro Val Gly 
1               5                   10                  15      


Ser Ser Ile Leu Val Gln Cys His Tyr Arg Leu Gln Asp Val Lys Ala 
            20                  25                  30          


Gln Lys Val Trp Cys Arg Phe Leu Pro Glu Gly Cys Gln Pro Leu Val 
        35                  40                  45              


Ser Ser Ala Val Asp Arg Arg Ala Pro Ala Gly Arg Arg Thr Phe Leu 
    50                  55                  60                  


Thr Asp Leu Gly Gly Gly Leu Leu Gln Val Glu Met Val Thr Leu Gln 
65                  70                  75                  80  


Glu Glu Asp Ala Gly Glu Tyr Gly Cys Met Val Asp Gly Ala Arg Gly 
                85                  90                  95      


Pro Gln Ile Leu His Arg Val Ser Leu Asn Ile Leu Pro Pro Glu Glu 
            100                 105                 110         


Glu Glu Glu Thr His Lys Ile Gly Ser Leu Ala Glu Asn Ala Phe Ser 
        115                 120                 125             


Asp Pro Ala Gly Ser Ala Asn Pro Leu Glu Pro Ser Gln Asp Glu Lys 
    130                 135                 140                 


Ser Ile Pro 
145         


<210>  1332
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  1332

Gly Pro Ser Ala Asp Ser Val Tyr Thr Lys Val Arg Leu Leu Glu Gly 
1               5                   10                  15      


Glu Thr Leu Ser Val Gln Cys Ser Tyr Lys Gly Tyr Lys Asn Arg Val 
            20                  25                  30          


Glu Gly Lys Val Trp Cys Lys Ile Arg Lys Lys Lys Cys Glu Pro Gly 
        35                  40                  45              


Phe Ala Arg Val Trp Val Lys Gly Pro Arg Tyr Leu Leu Gln Asp Asp 
    50                  55                  60                  


Ala Gln Ala Lys Val Val Asn Ile Thr Met Val Ala Leu Lys Leu Gln 
65                  70                  75                  80  


Asp Ser Gly Arg Tyr Trp Cys Met Arg Asn Thr Ser Gly Ile Leu Tyr 
                85                  90                  95      


Pro Leu Met Gly Phe Gln Leu Asp Val Ser Pro Ala Pro Gln Ser Glu 
            100                 105                 110         


Arg Asn Ile Pro Phe Thr His Leu Asp Asn Ile Leu Lys Ser Gly Thr 
        115                 120                 125             


Val Thr Thr Gly Gln Ala Pro Thr Ser Gly Pro Asp Ala Pro Phe Thr 
    130                 135                 140                 


Thr Gly Val Met Val Phe Thr Pro Gly Leu Ile Thr Leu Pro Arg Leu 
145                 150                 155                 160 


Leu Ala Ser Thr Arg Pro Ala Ser Lys Thr Gly Tyr Ser Phe Thr Ala 
                165                 170                 175     


Thr Ser Thr Thr Ser Gln Gly Pro Arg Arg Thr Met Gly Ser Gln Thr 
            180                 185                 190         


Val Thr Ala Ser Pro Ser Asn Ala Arg Asp Ser Ser Ala Gly Pro Glu 
        195                 200                 205             


Ser Ile Ser Thr Lys Ser Gly Asp Leu Ser Thr Arg Ser Pro Thr Thr 
    210                 215                 220                 


Gly Leu Cys Leu Thr Ser Arg Ser Leu Leu Asn Arg Leu Pro Ser Met 
225                 230                 235                 240 


Pro Ser Ile Arg His Gln Asp Val Tyr Ser 
                245                 250 


<210>  1333
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  1333

Glu Glu Leu His Lys His Pro Gly Gln Thr Leu Leu Leu Gln Cys Gln 
1               5                   10                  15      


Tyr Ser Pro Lys Arg Gly Pro Tyr Gln Pro Lys Ser Trp Cys Gln Gln 
            20                  25                  30          


Thr Ser Pro Ser Arg Cys Thr Leu Leu Val Thr Ser Ser Lys Pro Trp 
        35                  40                  45              


Thr Ala Val Gln Lys Ser His Tyr Thr Ile Trp Asp Lys Pro Asn Ala 
    50                  55                  60                  


Gly Phe Phe Asn Ile Thr Met Ile Gln Leu Thr Gln Asn Asp Ser Gly 
65                  70                  75                  80  


Phe Tyr Trp Cys Gly Ile Tyr Asn Ala Ser Glu Asn Ile Ile Thr Val 
                85                  90                  95      


Leu Arg Asn Ile Ser Leu Val Val Ser Pro Ala Pro Thr Thr Ser Pro 
            100                 105                 110         


Met Trp Thr Leu Pro Trp Leu Pro Thr Ser Thr Val Leu Ile Thr Ser 
        115                 120                 125             


Pro Glu Gly Thr Ser Gly His Pro Ser Ile Asn Gly Ser Glu Thr Arg 
    130                 135                 140                 


Lys Ser Arg Ala Pro Ala 
145                 150 


<210>  1334
<211>  671
<212>  PRT
<213>  Homo Sapiens

<400>  1334

Val Cys Pro Glu Arg Cys Asp Cys Gln His Pro Gln His Leu Leu Cys 
1               5                   10                  15      


Thr Asn Arg Gly Leu Arg Val Val Pro Lys Thr Ser Ser Leu Pro Ser 
            20                  25                  30          


Pro His Asp Val Leu Thr Tyr Ser Leu Gly Gly Asn Phe Ile Thr Asn 
        35                  40                  45              


Ile Thr Ala Phe Asp Phe His Arg Leu Gly Gln Leu Arg Arg Leu Asp 
    50                  55                  60                  


Leu Gln Tyr Asn Gln Ile Arg Ser Leu His Pro Lys Thr Phe Glu Lys 
65                  70                  75                  80  


Leu Ser Arg Leu Glu Glu Leu Tyr Leu Gly Asn Asn Leu Leu Gln Ala 
                85                  90                  95      


Leu Ala Pro Gly Thr Leu Ala Pro Leu Arg Lys Leu Arg Ile Leu Tyr 
            100                 105                 110         


Ala Asn Gly Asn Glu Ile Ser Arg Leu Ser Arg Gly Ser Phe Glu Gly 
        115                 120                 125             


Leu Glu Ser Leu Val Lys Leu Arg Leu Asp Gly Asn Ala Leu Gly Ala 
    130                 135                 140                 


Leu Pro Asp Ala Val Phe Ala Pro Leu Gly Asn Leu Leu Tyr Leu His 
145                 150                 155                 160 


Leu Glu Ser Asn Arg Ile Arg Phe Leu Gly Lys Asn Ala Phe Ala Gln 
                165                 170                 175     


Leu Gly Lys Leu Arg Phe Leu Asn Leu Ser Ala Asn Glu Leu Gln Pro 
            180                 185                 190         


Ser Leu Arg His Ala Ala Thr Phe Ala Pro Leu Arg Ser Leu Ser Ser 
        195                 200                 205             


Leu Ile Leu Ser Ala Asn Ser Leu Gln His Leu Gly Pro Arg Ile Phe 
    210                 215                 220                 


Gln His Leu Pro Arg Leu Gly Leu Leu Ser Leu Arg Gly Asn Gln Leu 
225                 230                 235                 240 


Thr His Leu Ala Pro Glu Ala Phe Trp Gly Leu Glu Ala Leu Arg Glu 
                245                 250                 255     


Leu Arg Leu Glu Gly Asn Arg Leu Ser Gln Leu Pro Thr Ala Leu Leu 
            260                 265                 270         


Glu Pro Leu His Ser Leu Glu Ala Leu Asp Leu Ser Gly Asn Glu Leu 
        275                 280                 285             


Ser Ala Leu His Pro Ala Thr Phe Gly His Leu Gly Arg Leu Arg Glu 
    290                 295                 300                 


Leu Ser Leu Arg Asn Asn Ala Leu Ser Ala Leu Ser Gly Asp Ile Phe 
305                 310                 315                 320 


Ala Ala Ser Pro Ala Leu Tyr Arg Leu Asp Leu Asp Gly Asn Gly Trp 
                325                 330                 335     


Thr Cys Asp Cys Arg Leu Arg Gly Leu Lys Arg Trp Met Gly Asp Trp 
            340                 345                 350         


His Ser Gln Gly Arg Leu Leu Thr Val Phe Val Gln Cys Arg His Pro 
        355                 360                 365             


Pro Ala Leu Arg Gly Lys Tyr Leu Asp Tyr Leu Asp Asp Gln Gln Leu 
    370                 375                 380                 


Gln Asn Gly Ser Cys Ala Asp Pro Ser Pro Ser Ala Ser Leu Thr Ala 
385                 390                 395                 400 


Asp Arg Arg Arg Gln Pro Leu Pro Thr Ala Ala Gly Glu Glu Met Thr 
                405                 410                 415     


Pro Pro Ala Gly Leu Ala Glu Glu Leu Pro Pro Gln Pro Gln Leu Gln 
            420                 425                 430         


Gln Gln Gly Arg Phe Leu Ala Gly Val Ala Trp Asp Gly Ala Ala Arg 
        435                 440                 445             


Glu Leu Val Gly Asn Arg Ser Ala Leu Arg Leu Ser Arg Arg Gly Pro 
    450                 455                 460                 


Gly Leu Gln Gln Pro Ser Pro Ser Val Ala Ala Ala Ala Gly Pro Ala 
465                 470                 475                 480 


Pro Gln Ser Leu Asp Leu His Lys Lys Pro Gln Arg Gly Arg Pro Thr 
                485                 490                 495     


Arg Ala Asp Pro Ala Leu Ala Glu Pro Thr Pro Thr Ala Ser Pro Gly 
            500                 505                 510         


Ser Ala Pro Ser Pro Ala Gly Asp Pro Trp Gln Arg Ala Thr Lys His 
        515                 520                 525             


Arg Leu Gly Thr Glu His Gln Glu Arg Ala Ala Gln Ser Asp Gly Gly 
    530                 535                 540                 


Ala Gly Leu Pro Pro Leu Val Ser Asp Pro Cys Asp Phe Asn Lys Phe 
545                 550                 555                 560 


Ile Leu Cys Asn Leu Thr Val Glu Ala Val Gly Ala Asp Ser Ala Ser 
                565                 570                 575     


Val Arg Trp Ala Val Arg Glu His Arg Ser Pro Arg Pro Leu Gly Gly 
            580                 585                 590         


Ala Arg Phe Arg Leu Leu Phe Asp Arg Phe Gly Gln Gln Pro Lys Phe 
        595                 600                 605             


His Arg Phe Val Tyr Leu Pro Glu Ser Ser Asp Ser Ala Thr Leu Arg 
    610                 615                 620                 


Glu Leu Arg Gly Asp Thr Pro Tyr Leu Val Cys Val Glu Gly Val Leu 
625                 630                 635                 640 


Gly Gly Arg Val Cys Pro Val Ala Pro Arg Asp His Cys Ala Gly Leu 
                645                 650                 655     


Val Thr Leu Pro Glu Ala Gly Ser Arg Gly Gly Val Asp Tyr Gln 
            660                 665                 670     


<210>  1335
<211>  393
<212>  PRT
<213>  Homo Sapiens

<400>  1335

Gly Met Gly Cys Ser Ser Pro Pro Cys Glu Cys His Gln Glu Glu Asp 
1               5                   10                  15      


Phe Arg Val Thr Cys Lys Asp Ile Gln Arg Ile Pro Ser Leu Pro Pro 
            20                  25                  30          


Ser Thr Gln Thr Leu Lys Leu Ile Glu Thr His Leu Arg Thr Ile Pro 
        35                  40                  45              


Ser His Ala Phe Ser Asn Leu Pro Asn Ile Ser Arg Ile Tyr Val Ser 
    50                  55                  60                  


Ile Asp Val Thr Leu Gln Gln Leu Glu Ser His Ser Phe Tyr Asn Leu 
65                  70                  75                  80  


Ser Lys Val Thr His Ile Glu Ile Arg Asn Thr Arg Asn Leu Thr Tyr 
                85                  90                  95      


Ile Asp Pro Asp Ala Leu Lys Glu Leu Pro Leu Leu Lys Phe Leu Gly 
            100                 105                 110         


Ile Phe Asn Thr Gly Leu Lys Met Phe Pro Asp Leu Thr Lys Val Tyr 
        115                 120                 125             


Ser Thr Asp Ile Phe Phe Ile Leu Glu Ile Thr Asp Asn Pro Tyr Met 
    130                 135                 140                 


Thr Ser Ile Pro Val Asn Ala Phe Gln Gly Leu Cys Asn Glu Thr Leu 
145                 150                 155                 160 


Thr Leu Lys Leu Tyr Asn Asn Gly Phe Thr Ser Val Gln Gly Tyr Ala 
                165                 170                 175     


Phe Asn Gly Thr Lys Leu Asp Ala Val Tyr Leu Asn Lys Asn Lys Tyr 
            180                 185                 190         


Leu Thr Val Ile Asp Lys Asp Ala Phe Gly Gly Val Tyr Ser Gly Pro 
        195                 200                 205             


Ser Leu Leu Asp Val Ser Gln Thr Ser Val Thr Ala Leu Pro Ser Lys 
    210                 215                 220                 


Gly Leu Glu His Leu Lys Glu Leu Ile Ala Arg Asn Thr Trp Thr Leu 
225                 230                 235                 240 


Lys Lys Leu Pro Leu Ser Leu Ser Phe Leu His Leu Thr Arg Ala Asp 
                245                 250                 255     


Leu Ser Tyr Pro Ser His Cys Cys Ala Phe Lys Asn Gln Lys Lys Ile 
            260                 265                 270         


Arg Gly Ile Leu Glu Ser Leu Met Cys Asn Glu Ser Ser Met Gln Ser 
        275                 280                 285             


Leu Arg Gln Arg Lys Ser Val Asn Ala Leu Asn Ser Pro Leu His Gln 
    290                 295                 300                 


Glu Tyr Glu Glu Asn Leu Gly Asp Ser Ile Val Gly Tyr Lys Glu Lys 
305                 310                 315                 320 


Ser Lys Phe Gln Asp Thr His Asn Asn Ala His Tyr Tyr Val Phe Phe 
                325                 330                 335     


Glu Glu Gln Glu Asp Glu Ile Ile Gly Phe Gly Gln Glu Leu Lys Asn 
            340                 345                 350         


Pro Gln Glu Glu Thr Leu Gln Ala Phe Asp Ser His Tyr Asp Tyr Thr 
        355                 360                 365             


Ile Cys Gly Asp Ser Glu Asp Met Val Cys Thr Pro Lys Ser Asp Glu 
    370                 375                 380                 


Phe Asn Pro Cys Glu Asp Ile Met Gly 
385                 390             


<210>  1336
<211>  337
<212>  PRT
<213>  Homo Sapiens

<400>  1336

Thr Arg Pro Cys Phe Pro Gly Cys Gln Cys Glu Val Glu Thr Phe Gly 
1               5                   10                  15      


Leu Phe Asp Ser Phe Ser Leu Thr Arg Val Asp Cys Ser Gly Leu Gly 
            20                  25                  30          


Pro His Ile Met Pro Val Pro Ile Pro Leu Asp Thr Ala His Leu Asp 
        35                  40                  45              


Leu Ser Ser Asn Arg Leu Glu Met Val Asn Glu Ser Val Leu Ala Gly 
    50                  55                  60                  


Pro Gly Tyr Thr Thr Leu Ala Gly Leu Asp Leu Ser His Asn Leu Leu 
65                  70                  75                  80  


Thr Ser Ile Ser Pro Thr Ala Phe Ser Arg Leu Arg Tyr Leu Glu Ser 
                85                  90                  95      


Leu Asp Leu Ser His Asn Gly Leu Thr Ala Leu Pro Ala Glu Ser Phe 
            100                 105                 110         


Thr Ser Ser Pro Leu Ser Asp Val Asn Leu Ser His Asn Gln Leu Arg 
        115                 120                 125             


Glu Val Ser Val Ser Ala Phe Thr Thr His Ser Gln Gly Arg Ala Leu 
    130                 135                 140                 


His Val Asp Leu Ser His Asn Leu Ile His Arg Leu Val Pro His Pro 
145                 150                 155                 160 


Thr Arg Ala Gly Leu Pro Ala Pro Thr Ile Gln Ser Leu Asn Leu Ala 
                165                 170                 175     


Trp Asn Arg Leu His Ala Val Pro Asn Leu Arg Asp Leu Pro Leu Arg 
            180                 185                 190         


Tyr Leu Ser Leu Asp Gly Asn Pro Leu Ala Val Ile Gly Pro Gly Ala 
        195                 200                 205             


Phe Ala Gly Leu Gly Gly Leu Thr His Leu Ser Leu Ala Ser Leu Gln 
    210                 215                 220                 


Arg Leu Pro Glu Leu Ala Pro Ser Gly Phe Arg Glu Leu Pro Gly Leu 
225                 230                 235                 240 


Gln Val Leu Asp Leu Ser Gly Asn Pro Lys Leu Asn Trp Ala Gly Ala 
                245                 250                 255     


Glu Val Phe Ser Gly Leu Ser Ser Leu Gln Glu Leu Asp Leu Ser Gly 
            260                 265                 270         


Thr Asn Leu Val Pro Leu Pro Glu Ala Leu Leu Leu His Leu Pro Ala 
        275                 280                 285             


Leu Gln Ser Val Ser Val Gly Gln Asp Val Arg Cys Arg Arg Leu Val 
    290                 295                 300                 


Arg Glu Gly Thr Tyr Pro Arg Arg Pro Gly Ser Ser Pro Lys Val Ala 
305                 310                 315                 320 


Leu His Cys Val Asp Thr Arg Asp Ser Ala Ala Arg Gly Pro Thr Ile 
                325                 330                 335     


Leu 
    


<210>  1337
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  1337

Tyr Asp Phe Thr Asn Cys Asp Phe Glu Lys Ile Lys Ala Ala Tyr Leu 
1               5                   10                  15      


Ser Thr Ile Ser Lys Asp Leu Ile Thr Tyr Met Ser Gly Thr Lys Ser 
            20                  25                  30          


Thr Glu Phe Asn Asn Thr Val Ser Cys Ser Asn Arg Pro His Cys Leu 
        35                  40                  45              


Thr Glu Ile Gln Ser Leu Thr Phe Asn Pro Thr Ala Gly Cys Ala Ser 
    50                  55                  60                  


Leu Ala Lys Glu Met Phe Ala Met Lys Thr Lys Ala Ala Leu Ala Ile 
65                  70                  75                  80  


Trp Cys Pro Gly Tyr Ser Glu Thr Gln Ile Asn Ala Thr Gln Ala Met 
                85                  90                  95      


Lys Lys Arg Arg Lys Arg Lys Val Thr Thr Asn Lys Cys Leu Glu Gln 
            100                 105                 110         


Val Ser Gln Leu Gln Gly Leu Trp Arg Arg Phe Asn Arg Pro Leu Leu 
        115                 120                 125             


Lys Gln Gln 
    130     


<210>  1338
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  1338

Tyr Thr Thr Met Ala Glu His Phe Leu Thr Leu Leu Val Val Pro Ala 
1               5                   10                  15      


Ile Lys Lys Asp Tyr Gly Ser Gln Glu Asp Phe Thr Gln Val Trp Asn 
            20                  25                  30          


Thr Thr Met Lys Gly Leu Lys Cys Cys Gly Phe Thr Asn Tyr Thr Asp 
        35                  40                  45              


Phe Glu Asp Ser Pro Tyr Phe Lys Glu Asn Ser Ala Phe Pro Pro Phe 
    50                  55                  60                  


Cys Cys Asn Asp Asn Val Thr Asn Thr Ala Asn Glu Thr Cys Thr Lys 
65                  70                  75                  80  


Gln Lys Ala His Asp Gln Lys Val Glu Gly Cys Phe Asn Gln Leu Leu 
                85                  90                  95      


Tyr Asp Ile Arg Thr Asn 
            100         


<210>  1339
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  1339

Gly Val Trp Thr Tyr Glu Gln Glu Leu Met Val Pro Val Gln Trp Ser 
1               5                   10                  15      


Asp Met Val Thr Leu Lys Ala Arg Met Thr Asn Tyr Gly Leu Pro Arg 
            20                  25                  30          


Tyr Arg Trp Leu Thr His Ala Trp Asn Phe Phe Gln Arg Glu Phe Lys 
        35                  40                  45              


Cys Cys Gly Val Val Tyr Phe Thr Asp Trp Leu Glu Met Thr Glu Met 
    50                  55                  60                  


Asp Trp Pro Pro Asp Ser Cys Cys Val Arg Glu Phe Pro Gly Cys Ser 
65                  70                  75                  80  


Lys Gln Ala His Gln Glu Asp Leu Ser Asp Leu Tyr Gln Glu Gly Cys 
                85                  90                  95      


Gly Lys Lys Met Tyr Ser Phe Leu Arg Gly Thr Lys Gln Leu Gln Val 
            100                 105                 110         


Leu Arg 
        


<210>  1340
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  1340

Cys Ala Cys Leu Ala Leu Asn Gln Glu Gln Gln Gly Gln Leu Leu Glu 
1               5                   10                  15      


Val Gly Trp Asn Asn Thr Ala Ser Ala Arg Asn Asp Ile Gln Arg Asn 
            20                  25                  30          


Leu Asn Cys Cys Gly Phe Arg Ser Val Asn Pro Asn Asp Thr Cys Leu 
        35                  40                  45              


Ala Ser Cys Val Lys Ser Asp His Ser Cys Ser Pro Cys Ala Pro Ile 
    50                  55                  60                  


Ile Gly Glu Tyr Ala Gly Glu Val Leu Arg 
65                  70                  


<210>  1341
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1341

Thr Phe Arg Asn Gln Thr Ile Asp Phe Leu Asn Asp Asn Ile Arg Arg 
1               5                   10                  15      


Gly Ile Glu Asn Tyr Tyr Asp Asp Leu Asp Phe Lys Asn Ile Met Asp 
            20                  25                  30          


Phe Val Gln Lys Lys Phe Lys Cys Cys Gly Gly Glu Asp Tyr Arg Asp 
        35                  40                  45              


Trp Ser Lys Asn Gln Tyr His Asp Cys Ser Ala Pro Gly Pro Leu Ala 
    50                  55                  60                  


Cys Gly Val Pro Tyr Thr Cys Cys Ile Arg Asn Thr Thr Glu Val Val 
65                  70                  75                  80  


Asn Thr Met Cys Gly Tyr Lys Thr Ile Asp Lys Glu Arg Phe Ser Val 
                85                  90                  95      


Gln Asp Val Ile Tyr Val Arg Gly Cys Thr Asn Ala Val Ile Ile Trp 
            100                 105                 110         


Phe Met Asp Asn Tyr Thr Ile Met Ala 
        115                 120     


<210>  1342
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1342

Val Phe Lys Asp Trp Ile Arg Asp Gln Leu Asn Leu Phe Ile Asn Asn 
1               5                   10                  15      


Asn Val Lys Ala Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile Asp 
            20                  25                  30          


Phe Ala Gln Glu Tyr Trp Ser Cys Cys Gly Ala Arg Gly Pro Asn Asp 
        35                  40                  45              


Trp Asn Leu Asn Ile Tyr Phe Asn Cys Thr Asp Leu Asn Pro Ser Arg 
    50                  55                  60                  


Glu Arg Cys Gly Val Pro Phe Ser Cys Cys Val Arg Asp Pro Ala Glu 
65                  70                  75                  80  


Asp Val Leu Asn Thr Gln Cys Gly Tyr Asp Val Arg Leu Lys Leu Glu 
                85                  90                  95      


Leu Glu Gln Gln Gly Phe Ile His Thr Lys Gly Cys Val Gly Gln Phe 
            100                 105                 110         


Glu Lys Trp Leu Gln Asp Asn 
        115                 


<210>  1343
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1343

Ala Phe Ile Phe Arg Glu Asn Leu Thr Arg Glu Phe Phe Thr Lys Glu 
1               5                   10                  15      


Leu Thr Lys His Tyr Gln Gly Asn Asn Asp Thr Asp Val Phe Ser Ala 
            20                  25                  30          


Thr Trp Asn Ser Val Met Ile Thr Phe Gly Cys Cys Gly Val Asn Gly 
        35                  40                  45              


Pro Glu Asp Phe Lys Phe Ala Ser Val Phe Arg Leu Leu Thr Leu Asp 
    50                  55                  60                  


Ser Glu Glu Val Pro Glu Ala Cys Cys Arg Arg Glu Pro Gln Ser Arg 
65                  70                  75                  80  


Asp Gly Val Leu Leu Ser Arg Glu Glu Cys Leu Leu Gly Arg Ser Leu 
                85                  90                  95      


Phe Leu Asn Lys Gln Gly Cys Tyr Thr Val Ile Leu Asn Thr Phe Glu 
            100                 105                 110         


Thr Tyr Val Tyr Leu Ala Gly 
        115                 


<210>  1344
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1344

Gly Lys Gly Val Ala Ile Arg His Val Gln Thr Met Tyr Glu Glu Ala 
1               5                   10                  15      


Tyr Asn Asp Tyr Leu Lys Asp Arg Gly Lys Gly Asn Gly Thr Leu Ile 
            20                  25                  30          


Thr Phe His Ser Thr Phe Gln Cys Cys Gly Lys Glu Ser Ser Glu Gln 
        35                  40                  45              


Val Gln Pro Thr Cys Pro Lys Glu Leu Leu Gly His Lys Asn Cys Ile 
    50                  55                  60                  


Asp Glu Ile Glu Thr Ile Ile Ser Val Lys Leu Gln Leu 
65                  70                  75          


<210>  1345
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  1345

Tyr Arg Ala Lys Val Glu Asn Glu Val Asp Arg Ser Ile Gln Lys Val 
1               5                   10                  15      


Tyr Lys Thr Tyr Asn Gly Thr Asn Pro Asp Ala Ala Ser Arg Ala Ile 
            20                  25                  30          


Asp Tyr Val Gln Arg Gln Leu His Cys Cys Gly Ile His Asn Tyr Ser 
        35                  40                  45              


Asp Trp Glu Asn Thr Asp Trp Phe Lys Glu Thr Lys Asn Gln Ser Val 
    50                  55                  60                  


Pro Leu Ser Cys Cys Arg Glu Thr Ala Ser Asn Cys Asn Gly Ser Leu 
65                  70                  75                  80  


Ala His Pro Ser Asp Leu Tyr Ala Glu Gly Cys Glu Ala Leu Val Val 
                85                  90                  95      


Lys Lys Leu Gln Glu Ile Met Met His Val 
            100                 105     


<210>  1346
<211>  80
<212>  PRT
<213>  Homo Sapiens

<400>  1346

Cys Ser Cys Leu Ala Ile Asn Arg Ser Lys Gln Thr Asp Val Ile Asn 
1               5                   10                  15      


Ala Ser Trp Trp Val Met Ser Asn Lys Thr Arg Asp Glu Leu Glu Arg 
            20                  25                  30          


Ser Phe Asp Cys Cys Gly Leu Phe Asn Leu Thr Thr Leu Tyr Gln Gln 
        35                  40                  45              


Asp Tyr Asp Phe Cys Thr Ala Ile Cys Lys Ser Gln Ser Pro Thr Cys 
    50                  55                  60                  


Gln Met Cys Gly Glu Lys Phe Leu Lys His Ser Asp Glu Ala Leu Lys 
65                  70                  75                  80  


<210>  1347
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  1347

Phe Ser Asp Lys Ala Arg Gly Lys Val Ser Glu Ile Ile Asn Asn Ala 
1               5                   10                  15      


Ile Val His Tyr Arg Asp Asp Leu Asp Leu Gln Asn Leu Ile Asp Phe 
            20                  25                  30          


Gly Gln Lys Lys Phe Ser Cys Cys Gly Gly Ile Ser Tyr Lys Asp Trp 
        35                  40                  45              


Ser Gln Asn Met Tyr Phe Asn Cys Ser Glu Asp Asn Pro Ser Arg Glu 
    50                  55                  60                  


Arg Cys Ser Val Pro Tyr Ser Cys Cys Leu Pro Thr Pro Asp Gln Ala 
65                  70                  75                  80  


Val Ile Asn Thr Met Cys Gly Gln Gly Met Gln Ala Phe Asp Tyr Leu 
                85                  90                  95      


Glu Ala Ser Lys Val Ile Tyr Thr Asn Gly Cys Ile Asp Lys Leu Val 
            100                 105                 110         


Asn Trp Ile His Ser Asn 
        115             


<210>  1348
<211>  95
<212>  PRT
<213>  Homo Sapiens

<400>  1348

Tyr Thr Asp Lys Ile Asp Arg Tyr Ala Gln Gln Asp Leu Lys Lys Gly 
1               5                   10                  15      


Leu His Leu Tyr Gly Thr Gln Gly Asn Val Gly Leu Thr Asn Ala Trp 
            20                  25                  30          


Ser Ile Ile Gln Thr Asp Phe Arg Cys Cys Gly Val Ser Asn Tyr Thr 
        35                  40                  45              


Asp Trp Phe Glu Val Tyr Asn Ala Thr Arg Val Pro Asp Ser Cys Cys 
    50                  55                  60                  


Leu Glu Phe Ser Glu Ser Cys Gly Leu His Ala Pro Gly Thr Trp Trp 
65                  70                  75                  80  


Lys Ala Pro Cys Tyr Glu Thr Val Lys Val Trp Leu Gln Glu Asn 
                85                  90                  95  


<210>  1349
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1349

Val Phe Lys Asp Trp Ile Lys Asp Gln Leu Tyr Phe Phe Ile Asn Asn 
1               5                   10                  15      


Asn Ile Arg Ala Tyr Arg Asp Asp Ile Asp Leu Gln Asn Leu Ile Asp 
            20                  25                  30          


Phe Thr Gln Glu Tyr Trp Gln Cys Cys Gly Ala Phe Gly Ala Asp Asp 
        35                  40                  45              


Trp Asn Leu Asn Ile Tyr Phe Asn Cys Thr Asp Ser Asn Ala Ser Arg 
    50                  55                  60                  


Glu Arg Cys Gly Val Pro Phe Ser Cys Cys Thr Lys Asp Pro Ala Glu 
65                  70                  75                  80  


Asp Val Ile Asn Thr Gln Cys Gly Tyr Asp Ala Arg Gln Lys Pro Glu 
                85                  90                  95      


Val Asp Gln Gln Ile Val Ile Tyr Thr Lys Gly Cys Val Pro Gln Phe 
            100                 105                 110         


Glu Lys Trp Leu Gln Asp Asn 
        115                 


<210>  1350
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  1350

Arg His Glu Ile Lys Asp Thr Phe Leu Arg Thr Tyr Thr Asp Thr Met 
1               5                   10                  15      


Gln Thr Tyr Asn Gly Asn Asp Glu Arg Ser Arg Ala Val Asp His Val 
            20                  25                  30          


Gln Arg Ser Leu Ser Cys Cys Gly Val Gln Asn Tyr Thr Asn Trp Ser 
        35                  40                  45              


Thr Ser Pro Tyr Phe Leu Glu His Gly Ile Pro Pro Ser Cys Cys Met 
    50                  55                  60                  


Asn Glu Thr Asp Cys Asn Pro Gln Asp Leu His Asn Leu Thr Val Ala 
65                  70                  75                  80  


Ala Thr Lys Val Asn Gln Lys Gly Cys Tyr Asp Leu Val Thr Ser Phe 
                85                  90                  95      


Met Glu Thr Asn Met 
            100     


<210>  1351
<211>  96
<212>  PRT
<213>  Homo Sapiens

<400>  1351

Lys Ser Lys Ser Asp Arg Ile Val Asn Glu Thr Leu Tyr Glu Asn Thr 
1               5                   10                  15      


Lys Leu Leu Ser Ala Thr Gly Glu Ser Glu Lys Gln Phe Gln Glu Ala 
            20                  25                  30          


Ile Ile Val Phe Gln Glu Glu Phe Lys Cys Cys Gly Leu Val Asn Gly 
        35                  40                  45              


Ala Ala Asp Trp Gly Asn Asn Phe Gln His Tyr Pro Glu Leu Cys Ala 
    50                  55                  60                  


Cys Leu Asp Lys Gln Arg Pro Cys Gln Ser Tyr Asn Gly Lys Gln Val 
65                  70                  75                  80  


Tyr Lys Glu Thr Cys Ile Ser Phe Ile Lys Asp Phe Leu Ala Lys Asn 
                85                  90                  95      


<210>  1352
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1352

Tyr Met Asp Lys Val Asn Glu Asn Ala Lys Lys Asp Leu Lys Glu Gly 
1               5                   10                  15      


Leu Leu Leu Tyr His Thr Glu Asn Asn Val Gly Leu Lys Asn Ala Trp 
            20                  25                  30          


Asn Ile Ile Gln Ala Glu Met Arg Cys Cys Gly Val Thr Asp Tyr Thr 
        35                  40                  45              


Asp Trp Tyr Pro Val Leu Gly Glu Asn Thr Val Pro Asp Arg Cys Cys 
    50                  55                  60                  


Met Glu Asn Ser Gln Gly Cys Gly Arg Asn Ala Thr Thr Pro Leu Trp 
65                  70                  75                  80  


Arg Thr Gly Cys Tyr Glu Lys Val Lys Met Trp Phe Asp Asp Asn Lys 
                85                  90                  95      


His 
    


<210>  1353
<211>  389
<212>  PRT
<213>  Homo Sapiens

<400>  1353

Ala Gly Leu Lys Leu Met Gly Ala Pro Val Lys Leu Thr Val Ser Gln 
1               5                   10                  15      


Gly Gln Pro Val Lys Leu Asn Cys Ser Val Glu Gly Met Glu Glu Pro 
            20                  25                  30          


Asp Ile Gln Trp Val Lys Asp Gly Ala Val Val Gln Asn Leu Asp Gln 
        35                  40                  45              


Leu Tyr Ile Pro Val Ser Glu Gln His Trp Ile Gly Phe Leu Ser Leu 
    50                  55                  60                  


Lys Ser Val Glu Arg Ser Asp Ala Gly Arg Tyr Trp Cys Gln Val Glu 
65                  70                  75                  80  


Asp Gly Gly Glu Thr Glu Ile Ser Gln Pro Val Trp Leu Thr Val Glu 
                85                  90                  95      


Gly Val Pro Phe Phe Thr Val Glu Pro Lys Asp Leu Ala Val Pro Pro 
            100                 105                 110         


Asn Ala Pro Phe Gln Leu Ser Cys Glu Ala Val Gly Pro Pro Glu Pro 
        115                 120                 125             


Val Thr Ile Val Trp Trp Arg Gly Thr Thr Lys Ile Gly Gly Pro Ala 
    130                 135                 140                 


Pro Ser Pro Ser Val Leu Asn Val Thr Gly Val Thr Gln Ser Thr Met 
145                 150                 155                 160 


Phe Ser Cys Glu Ala His Asn Leu Lys Gly Leu Ala Ser Ser Arg Thr 
                165                 170                 175     


Ala Thr Val His Leu Gln Ala Leu Pro Ala Ala Pro Phe Asn Ile Thr 
            180                 185                 190         


Val Thr Lys Leu Ser Ser Ser Asn Ala Ser Val Ala Trp Met Pro Gly 
        195                 200                 205             


Ala Asp Gly Arg Ala Leu Leu Gln Ser Cys Thr Val Gln Val Thr Gln 
    210                 215                 220                 


Ala Pro Gly Gly Trp Glu Val Leu Ala Val Val Val Pro Val Pro Pro 
225                 230                 235                 240 


Phe Thr Cys Leu Leu Arg Asp Leu Val Pro Ala Thr Asn Tyr Ser Leu 
                245                 250                 255     


Arg Val Arg Cys Ala Asn Ala Leu Gly Pro Ser Pro Tyr Ala Asp Trp 
            260                 265                 270         


Val Pro Phe Gln Thr Lys Gly Leu Ala Pro Ala Ser Ala Pro Gln Asn 
        275                 280                 285             


Leu His Ala Ile Arg Thr Asp Ser Gly Leu Ile Leu Glu Trp Glu Glu 
    290                 295                 300                 


Val Ile Pro Glu Ala Pro Leu Glu Gly Pro Leu Gly Pro Tyr Lys Leu 
305                 310                 315                 320 


Ser Trp Val Gln Asp Asn Gly Thr Gln Asp Glu Leu Thr Val Glu Gly 
                325                 330                 335     


Thr Arg Ala Asn Leu Thr Gly Trp Asp Pro Gln Lys Asp Leu Ile Val 
            340                 345                 350         


Arg Val Cys Val Ser Asn Ala Val Gly Cys Gly Pro Trp Ser Gln Pro 
        355                 360                 365             


Leu Val Val Ser Ser His Asp Arg Ala Gly Gln Gln Gly Pro Pro His 
    370                 375                 380                 


Ser Arg Thr Ser Trp 
385                 


<210>  1354
<211>  19
<212>  PRT
<213>  Homo Sapiens

<400>  1354

Leu Arg Pro Val Gln Ala Gln Ala Gln Ser Asp Cys Ser Cys Ser Thr 
1               5                   10                  15      


Val Ser Pro 
            


<210>  1355
<211>  561
<212>  PRT
<213>  Homo Sapiens

<400>  1355

Asp Thr Ser Glu Ala Arg Trp Cys Ser Glu Cys His Ser Asn Ala Thr 
1               5                   10                  15      


Cys Thr Glu Asp Glu Ala Val Thr Thr Cys Thr Cys Gln Glu Gly Phe 
            20                  25                  30          


Thr Gly Asp Gly Leu Thr Cys Val Asp Leu Asp Glu Cys Ala Ile Pro 
        35                  40                  45              


Gly Ala His Asn Cys Ser Ala Asn Ser Ser Cys Val Asn Thr Pro Gly 
    50                  55                  60                  


Ser Phe Ser Cys Val Cys Pro Glu Gly Phe Arg Leu Ser Pro Gly Leu 
65                  70                  75                  80  


Gly Cys Thr Asp Val Asp Glu Cys Ala Glu Pro Gly Leu Ser His Cys 
                85                  90                  95      


His Ala Leu Ala Thr Cys Val Asn Val Val Gly Ser Tyr Leu Cys Val 
            100                 105                 110         


Cys Pro Ala Gly Tyr Arg Gly Asp Gly Trp His Cys Glu Cys Ser Pro 
        115                 120                 125             


Gly Ser Cys Gly Pro Gly Leu Asp Cys Val Pro Glu Gly Asp Ala Leu 
    130                 135                 140                 


Val Cys Ala Asp Pro Cys Gln Ala His Arg Thr Leu Asp Glu Tyr Trp 
145                 150                 155                 160 


Arg Ser Thr Glu Tyr Gly Glu Gly Tyr Ala Cys Asp Thr Asp Leu Arg 
                165                 170                 175     


Gly Trp Tyr Arg Pro His Pro Ser Ser Asp Glu Gly Ile Val Ser Arg 
            180                 185                 190         


Lys Ala Cys Ala His Trp Ser Gly His Cys Cys Leu Trp Asp Ala Ser 
        195                 200                 205             


Val Gln Val Lys Ala Cys Ala Gly Gly Tyr Tyr Val Tyr Asn Leu Thr 
    210                 215                 220                 


Ala Pro Pro Glu Cys His Leu Ala Tyr Cys Thr Asp Pro Ser Ser Val 
225                 230                 235                 240 


Glu Gly Thr Cys Glu Glu Cys Ser Ile Asp Glu Asp Cys Lys Ser Asn 
                245                 250                 255     


Asn Gly Arg Trp His Cys Gln Cys Lys Gln Asp Phe Asn Ile Thr Asp 
            260                 265                 270         


Ile Ser Leu Leu Glu His Arg Leu Glu Cys Gly Ala Asn Asp Met Lys 
        275                 280                 285             


Val Ser Leu Gly Lys Cys Gln Leu Lys Ser Leu Gly Phe Asp Lys Val 
    290                 295                 300                 


Phe Met Tyr Leu Ser Asp Ser Arg Cys Ser Gly Phe Asn Asp Arg Asp 
305                 310                 315                 320 


Asn Arg Asp Trp Val Ser Val Val Thr Pro Ala Arg Asp Gly Pro Cys 
                325                 330                 335     


Gly Thr Val Leu Thr Arg Asn Glu Thr His Ala Thr Tyr Ser Asn Thr 
            340                 345                 350         


Leu Tyr Leu Ala Asp Glu Ile Ile Ile Arg Asp Leu Asn Ile Lys Ile 
        355                 360                 365             


Asn Phe Ala Cys Ser Tyr Pro Leu Asp Met Lys Val Ser Leu Lys Thr 
    370                 375                 380                 


Ala Leu Gln Pro Met Val Ser Ala Leu Asn Ile Arg Val Gly Gly Thr 
385                 390                 395                 400 


Gly Met Phe Thr Val Arg Met Ala Leu Phe Gln Thr Pro Ser Tyr Thr 
                405                 410                 415     


Gln Pro Tyr Gln Gly Ser Ser Val Thr Leu Ser Thr Glu Ala Phe Leu 
            420                 425                 430         


Tyr Val Gly Thr Met Leu Asp Gly Gly Asp Leu Ser Arg Phe Ala Leu 
        435                 440                 445             


Leu Met Thr Asn Cys Tyr Ala Thr Pro Ser Ser Asn Ala Thr Asp Pro 
    450                 455                 460                 


Leu Lys Tyr Phe Ile Ile Gln Asp Arg Cys Pro His Thr Arg Asp Ser 
465                 470                 475                 480 


Thr Ile Gln Val Val Glu Asn Gly Glu Ser Ser Gln Gly Arg Phe Ser 
                485                 490                 495     


Val Gln Met Phe Arg Phe Ala Gly Asn Tyr Asp Leu Val Tyr Leu His 
            500                 505                 510         


Cys Glu Val Tyr Leu Cys Asp Thr Met Asn Glu Lys Cys Lys Pro Thr 
        515                 520                 525             


Cys Ser Gly Thr Arg Phe Arg Ser Gly Ser Val Ile Asp Gln Ser Arg 
    530                 535                 540                 


Val Leu Asn Leu Gly Pro Ile Thr Arg Lys Gly Val Gln Ala Thr Val 
545                 550                 555                 560 


Ser 
    


<210>  1356
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  1356

Gln Gln Ser Ala Thr Val Ala Asn Pro Val Pro Gly Ala Asn Pro Asp 
1               5                   10                  15      


Leu Leu Pro His Phe Leu Val Glu Pro Glu Asp Val Tyr Ile Val Lys 
            20                  25                  30          


Asn Lys Pro Val Leu Leu Val Cys Lys Ala Val Pro Ala Thr Gln Ile 
        35                  40                  45              


Phe Phe Lys Cys Asn Gly Glu Trp Val Arg Gln Val Asp His Val Ile 
    50                  55                  60                  


Glu Arg Ser Thr Asp Gly Ser Ser Gly Leu Pro Thr Met Glu Val Arg 
65                  70                  75                  80  


Ile Asn Val Ser Arg Gln Gln Val Glu Lys Val Phe Gly Leu Glu Glu 
                85                  90                  95      


Tyr Trp Cys Gln Cys Val Ala Trp Ser Ser Ser Gly Thr Thr Lys Ser 
            100                 105                 110         


Gln Lys Ala Tyr Ile Arg Ile Ala Tyr Leu Arg Lys Asn Phe Glu Gln 
        115                 120                 125             


Glu Pro Leu Ala Lys Glu Val Ser Leu Glu Gln Gly Ile Val Leu Pro 
    130                 135                 140                 


Cys Arg Pro Pro Glu Gly Ile Pro Pro Ala Glu Val Glu Trp Leu Arg 
145                 150                 155                 160 


Asn Glu Asp Leu Val Asp Pro Ser Leu Asp Pro Asn Val Tyr Ile Thr 
                165                 170                 175     


Arg Glu His Ser Leu Val Val Arg Gln Ala Arg Leu Ala Asp Thr Ala 
            180                 185                 190         


Asn Tyr Thr Cys Val Ala Lys Asn Ile Val Ala Arg Arg Arg Ser Ala 
        195                 200                 205             


Ser Ala Ala Val Ile Val Tyr Val Asp Gly Ser Trp Ser Pro Trp Ser 
    210                 215                 220                 


Lys Trp Ser Ala Cys Gly Leu Asp Cys Thr His Trp Arg Ser Arg Glu 
225                 230                 235                 240 


Cys Ser Asp Pro Ala Pro Arg Asn Gly Gly Glu Glu Cys Gln Gly Thr 
                245                 250                 255     


Asp Leu Asp Thr Arg Asn Cys Thr Ser Asp Leu Cys Val His Thr Ala 
            260                 265                 270         


Ser Gly Pro Glu Asp Val Ala Leu Tyr 
        275                 280     


<210>  1357
<211>  351
<212>  PRT
<213>  Homo Sapiens

<400>  1357

Gly Thr Asp Ser Gly Ser Glu Val Leu Pro Asp Ser Phe Pro Ser Ala 
1               5                   10                  15      


Pro Ala Glu Pro Leu Pro Tyr Phe Leu Gln Glu Pro Gln Asp Ala Tyr 
            20                  25                  30          


Ile Val Lys Asn Lys Pro Val Glu Leu Arg Cys Arg Ala Phe Pro Ala 
        35                  40                  45              


Thr Gln Ile Tyr Phe Lys Cys Asn Gly Glu Trp Val Ser Gln Asn Asp 
    50                  55                  60                  


His Val Thr Gln Glu Gly Leu Asp Glu Ala Thr Gly Leu Arg Val Arg 
65                  70                  75                  80  


Glu Val Gln Ile Glu Val Ser Arg Gln Gln Val Glu Glu Leu Phe Gly 
                85                  90                  95      


Leu Glu Asp Tyr Trp Cys Gln Cys Val Ala Trp Ser Ser Ala Gly Thr 
            100                 105                 110         


Thr Lys Ser Arg Arg Ala Tyr Val Arg Ile Ala Tyr Leu Arg Lys Asn 
        115                 120                 125             


Phe Asp Gln Glu Pro Leu Gly Lys Glu Val Pro Leu Asp His Glu Val 
    130                 135                 140                 


Leu Leu Gln Cys Arg Pro Pro Glu Gly Val Pro Val Ala Glu Val Glu 
145                 150                 155                 160 


Trp Leu Lys Asn Glu Asp Val Ile Asp Pro Thr Gln Asp Thr Asn Phe 
                165                 170                 175     


Leu Leu Thr Ile Asp His Asn Leu Ile Ile Arg Gln Ala Arg Leu Ser 
            180                 185                 190         


Asp Thr Ala Asn Tyr Thr Cys Val Ala Lys Asn Ile Val Ala Lys Arg 
        195                 200                 205             


Arg Ser Thr Thr Ala Thr Val Ile Val Tyr Val Asn Gly Gly Trp Ser 
    210                 215                 220                 


Ser Trp Ala Glu Trp Ser Pro Cys Ser Asn Arg Cys Gly Arg Gly Trp 
225                 230                 235                 240 


Gln Lys Arg Thr Arg Thr Cys Thr Asn Pro Ala Pro Leu Asn Gly Gly 
                245                 250                 255     


Ala Phe Cys Glu Gly Gln Ala Phe Gln Lys Thr Ala Cys Thr Thr Ile 
            260                 265                 270         


Cys Pro Val Asp Gly Ala Trp Thr Glu Trp Ser Lys Trp Ser Ala Cys 
        275                 280                 285             


Ser Thr Glu Cys Ala His Trp Arg Ser Arg Glu Cys Met Ala Pro Pro 
    290                 295                 300                 


Pro Gln Asn Gly Gly Arg Asp Cys Ser Gly Thr Leu Leu Asp Ser Lys 
305                 310                 315                 320 


Asn Cys Thr Asp Gly Leu Cys Met Gln Asn Lys Lys Thr Leu Ser Asp 
                325                 330                 335     


Pro Asn Ser His Leu Leu Glu Ala Ser Gly Asp Ala Ala Leu Tyr 
            340                 345                 350     


<210>  1358
<211>  359
<212>  PRT
<213>  Homo Sapiens

<400>  1358

Gln Asp Asp Asp Phe Phe His Glu Leu Pro Glu Thr Phe Pro Ser Asp 
1               5                   10                  15      


Pro Pro Glu Pro Leu Pro His Phe Leu Ile Glu Pro Glu Glu Ala Tyr 
            20                  25                  30          


Ile Val Lys Asn Lys Pro Val Asn Leu Tyr Cys Lys Ala Ser Pro Ala 
        35                  40                  45              


Thr Gln Ile Tyr Phe Lys Cys Asn Ser Glu Trp Val His Gln Lys Asp 
    50                  55                  60                  


His Ile Val Asp Glu Arg Val Asp Glu Thr Ser Gly Leu Ile Val Arg 
65                  70                  75                  80  


Glu Val Ser Ile Glu Ile Ser Arg Gln Gln Val Glu Glu Leu Phe Gly 
                85                  90                  95      


Pro Glu Asp Tyr Trp Cys Gln Cys Val Ala Trp Ser Ser Ala Gly Thr 
            100                 105                 110         


Thr Lys Ser Arg Lys Ala Tyr Val Arg Ile Ala Tyr Leu Arg Lys Thr 
        115                 120                 125             


Phe Glu Gln Glu Pro Leu Gly Lys Glu Val Ser Leu Glu Gln Glu Val 
    130                 135                 140                 


Leu Leu Gln Cys Arg Pro Pro Glu Gly Ile Pro Val Ala Glu Val Glu 
145                 150                 155                 160 


Trp Leu Lys Asn Glu Asp Ile Ile Asp Pro Val Glu Asp Arg Asn Phe 
                165                 170                 175     


Tyr Ile Ile Ile Asp His Asn Leu Ile Ile Lys Gln Ala Arg Leu Ser 
            180                 185                 190         


Asp Thr Ala Asn Tyr Thr Cys Val Ala Lys Asn Ile Val Ala Lys Arg 
        195                 200                 205             


Lys Ser Thr Thr Ala Thr Val Ile Val Tyr Val Asn Gly Gly Trp Ser 
    210                 215                 220                 


Thr Trp Thr Glu Trp Ser Val Cys Asn Ser Arg Cys Gly Arg Gly Tyr 
225                 230                 235                 240 


Gln Lys Arg Thr Arg Thr Cys Thr Asn Pro Ala Pro Leu Asn Gly Gly 
                245                 250                 255     


Ala Phe Cys Glu Gly Gln Ser Val Gln Lys Ile Ala Cys Thr Thr Leu 
            260                 265                 270         


Cys Pro Val Asp Gly Arg Trp Thr Pro Trp Ser Lys Trp Ser Thr Cys 
        275                 280                 285             


Gly Thr Glu Cys Thr His Trp Arg Arg Arg Glu Cys Thr Ala Pro Ala 
    290                 295                 300                 


Pro Lys Asn Gly Gly Lys Asp Cys Asp Gly Leu Val Leu Gln Ser Lys 
305                 310                 315                 320 


Asn Cys Thr Asp Gly Leu Cys Met Gln Ser Phe Ile Tyr Pro Ile Ser 
                325                 330                 335     


Thr Glu Gln Arg Thr Gln Asn Glu Tyr Gly Phe Ser Ser Ala Pro Asp 
            340                 345                 350         


Ser Asp Asp Val Ala Leu Tyr 
        355                 


<210>  1359
<211>  347
<212>  PRT
<213>  Homo Sapiens

<400>  1359

Ala Arg Gly Thr Asp Asn Gly Glu Ala Leu Pro Glu Ser Ile Pro Ser 
1               5                   10                  15      


Ala Pro Gly Thr Leu Pro His Phe Ile Glu Glu Pro Asp Asp Ala Tyr 
            20                  25                  30          


Ile Ile Lys Ser Asn Pro Ile Ala Leu Arg Cys Lys Ala Arg Pro Ala 
        35                  40                  45              


Met Gln Ile Phe Phe Lys Cys Asn Gly Glu Trp Val His Gln Asn Glu 
    50                  55                  60                  


His Val Ser Glu Glu Thr Leu Asp Glu Ser Ser Gly Leu Lys Val Arg 
65                  70                  75                  80  


Glu Val Phe Ile Asn Val Thr Arg Gln Gln Val Glu Asp Phe His Gly 
                85                  90                  95      


Pro Glu Asp Tyr Trp Cys Gln Cys Val Ala Trp Ser His Leu Gly Thr 
            100                 105                 110         


Ser Lys Ser Arg Lys Ala Ser Val Arg Ile Ala Tyr Leu Arg Lys Asn 
        115                 120                 125             


Phe Glu Gln Asp Pro Gln Gly Arg Glu Val Pro Ile Glu Gly Met Ile 
    130                 135                 140                 


Val Leu His Cys Arg Pro Pro Glu Gly Val Pro Ala Ala Glu Val Glu 
145                 150                 155                 160 


Trp Leu Lys Asn Glu Glu Pro Ile Asp Ser Glu Gln Asp Glu Asn Ile 
                165                 170                 175     


Asp Thr Arg Ala Asp His Asn Leu Ile Ile Arg Gln Ala Arg Leu Ser 
            180                 185                 190         


Asp Ser Gly Asn Tyr Thr Cys Met Ala Ala Asn Ile Val Ala Lys Arg 
        195                 200                 205             


Arg Ser Leu Ser Ala Thr Val Val Val Tyr Val Asn Gly Gly Trp Ser 
    210                 215                 220                 


Ser Trp Thr Glu Trp Ser Ala Cys Asn Val Arg Cys Gly Arg Gly Trp 
225                 230                 235                 240 


Gln Lys Arg Ser Arg Thr Cys Thr Asn Pro Ala Pro Leu Asn Gly Gly 
                245                 250                 255     


Ala Phe Cys Glu Gly Met Ser Val Gln Lys Ile Thr Cys Thr Ser Leu 
            260                 265                 270         


Cys Pro Val Asp Gly Ser Trp Glu Val Trp Ser Glu Trp Ser Val Cys 
        275                 280                 285             


Ser Pro Glu Cys Glu His Leu Arg Ile Arg Glu Cys Thr Ala Pro Pro 
    290                 295                 300                 


Pro Arg Asn Gly Gly Lys Phe Cys Glu Gly Leu Ser Gln Glu Ser Glu 
305                 310                 315                 320 


Asn Cys Thr Asp Gly Leu Cys Ile Leu Asp Lys Lys Pro Leu His Glu 
                325                 330                 335     


Ile Lys Pro Gln Ser Ile Glu Asn Ala Ser Asp 
            340                 345         


<210>  1360
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  1360

Thr Ser Tyr Thr His Arg Asp Tyr Met Val Ser Asn Pro Ser Leu Ile 
1               5                   10                  15      


Thr Lys Gln Met Leu Thr Phe Tyr Ser Ala Asp Thr Asp Gln Gly Gln 
            20                  25                  30          


Glu Leu Thr Arg Leu Trp Asp Arg Val Met Ile Glu Gln Glu Cys Cys 
        35                  40                  45              


Gly Thr Ser Gly Pro Met Asp Trp Val Asn Phe Thr Ser Ala Phe Arg 
    50                  55                  60                  


Ala Ala Thr Pro Glu Val Val Phe Pro Trp Pro Pro Leu Cys Cys Arg 
65                  70                  75                  80  


Arg Thr Gly Asn Phe Ile Pro Leu Asn Glu Glu Gly Cys Arg Leu Gly 
                85                  90                  95      


His Met Asp Tyr Leu Phe Thr Lys Ala Gly Val Gln Trp His Asn Leu 
            100                 105                 110         


Ser Ser Leu Gln Arg 
        115         


<210>  1361
<211>  122
<212>  PRT
<213>  Homo Sapiens

<400>  1361

Thr Ala Ala Thr Gln Arg Asp Phe Phe Thr Pro Asn Leu Phe Leu Lys 
1               5                   10                  15      


Gln Met Leu Glu Arg Tyr Gln Asn Asn Ser Pro Pro Asn Asn Asp Asp 
            20                  25                  30          


Gln Trp Lys Asn Asn Gly Val Thr Lys Thr Trp Asp Arg Leu Met Leu 
        35                  40                  45              


Gln Asp Asn Cys Cys Gly Val Asn Gly Pro Ser Asp Trp Gln Lys Tyr 
    50                  55                  60                  


Thr Ser Ala Phe Arg Thr Glu Asn Asn Asp Ala Asp Tyr Pro Trp Pro 
65                  70                  75                  80  


Arg Gln Cys Cys Val Met Asn Asn Leu Lys Glu Pro Leu Asn Leu Glu 
                85                  90                  95      


Ala Cys Lys Leu Gly Val Pro Gly Phe Tyr His Asn Gln Gly Cys Tyr 
            100                 105                 110         


Glu Leu Ile Ser Gly Pro Met Asn Arg His 
        115                 120         


<210>  1362
<211>  552
<212>  PRT
<213>  Homo Sapiens

<400>  1362

Cys Pro Ser Gly Cys Gln Cys Ser Gln Pro Gln Thr Val Phe Cys Thr 
1               5                   10                  15      


Ala Arg Gln Gly Thr Thr Val Pro Arg Asp Val Pro Pro Asp Thr Val 
            20                  25                  30          


Gly Leu Tyr Val Phe Glu Asn Gly Ile Thr Met Leu Asp Ala Gly Ser 
        35                  40                  45              


Phe Ala Gly Leu Pro Gly Leu Gln Leu Leu Asp Leu Ser Gln Asn Gln 
    50                  55                  60                  


Ile Ala Ser Leu Pro Ser Gly Val Phe Gln Pro Leu Ala Asn Leu Ser 
65                  70                  75                  80  


Asn Leu Asp Leu Thr Ala Asn Arg Leu His Glu Ile Thr Asn Glu Thr 
                85                  90                  95      


Phe Arg Gly Leu Arg Arg Leu Glu Arg Leu Tyr Leu Gly Lys Asn Arg 
            100                 105                 110         


Ile Arg His Ile Gln Pro Gly Ala Phe Asp Thr Leu Asp Arg Leu Leu 
        115                 120                 125             


Glu Leu Lys Leu Gln Asp Asn Glu Leu Arg Ala Leu Pro Pro Leu Arg 
    130                 135                 140                 


Leu Pro Arg Leu Leu Leu Leu Asp Leu Ser His Asn Ser Leu Leu Ala 
145                 150                 155                 160 


Leu Glu Pro Gly Ile Leu Asp Thr Ala Asn Val Glu Ala Leu Arg Leu 
                165                 170                 175     


Ala Gly Leu Gly Leu Gln Gln Leu Asp Glu Gly Leu Phe Ser Arg Leu 
            180                 185                 190         


Arg Asn Leu His Asp Leu Asp Val Ser Asp Asn Gln Leu Glu Arg Val 
        195                 200                 205             


Pro Pro Val Ile Arg Gly Leu Arg Gly Leu Thr Arg Leu Arg Leu Ala 
    210                 215                 220                 


Gly Asn Thr Arg Ile Ala Gln Leu Arg Pro Glu Asp Leu Ala Gly Leu 
225                 230                 235                 240 


Ala Ala Leu Gln Glu Leu Asp Val Ser Asn Leu Ser Leu Gln Ala Leu 
                245                 250                 255     


Pro Gly Asp Leu Ser Gly Leu Phe Pro Arg Leu Arg Leu Leu Ala Ala 
            260                 265                 270         


Ala Arg Asn Pro Phe Asn Cys Val Cys Pro Leu Ser Trp Phe Gly Pro 
        275                 280                 285             


Trp Val Arg Glu Ser His Val Thr Leu Ala Ser Pro Glu Glu Thr Arg 
    290                 295                 300                 


Cys His Phe Pro Pro Lys Asn Ala Gly Arg Leu Leu Leu Glu Leu Asp 
305                 310                 315                 320 


Tyr Ala Asp Phe Gly Cys Pro Ala Thr Thr Thr Thr Ala Thr Val Pro 
                325                 330                 335     


Thr Thr Arg Pro Val Val Arg Glu Pro Thr Ala Leu Ser Ser Ser Leu 
            340                 345                 350         


Ala Pro Thr Trp Leu Ser Pro Thr Ala Pro Ala Thr Glu Ala Pro Ser 
        355                 360                 365             


Pro Pro Ser Thr Ala Pro Pro Thr Val Gly Pro Val Pro Gln Pro Gln 
    370                 375                 380                 


Asp Cys Pro Pro Ser Thr Cys Leu Asn Gly Gly Thr Cys His Leu Gly 
385                 390                 395                 400 


Thr Arg His His Leu Ala Cys Leu Cys Pro Glu Gly Phe Thr Gly Leu 
                405                 410                 415     


Tyr Cys Glu Ser Gln Met Gly Gln Gly Thr Arg Pro Ser Pro Thr Pro 
            420                 425                 430         


Val Thr Pro Arg Pro Pro Arg Ser Leu Thr Leu Gly Ile Glu Pro Val 
        435                 440                 445             


Ser Pro Thr Ser Leu Arg Val Gly Leu Gln Arg Tyr Leu Gln Gly Ser 
    450                 455                 460                 


Ser Val Gln Leu Arg Ser Leu Arg Leu Thr Tyr Arg Asn Leu Ser Gly 
465                 470                 475                 480 


Pro Asp Lys Arg Leu Val Thr Leu Arg Leu Pro Ala Ser Leu Ala Glu 
                485                 490                 495     


Tyr Thr Val Thr Gln Leu Arg Pro Asn Ala Thr Tyr Ser Val Cys Val 
            500                 505                 510         


Met Pro Leu Gly Pro Gly Arg Val Pro Glu Gly Glu Glu Ala Cys Gly 
        515                 520                 525             


Glu Ala His Thr Pro Pro Ala Val His Ser Asn His Ala Pro Val Thr 
    530                 535                 540                 


Gln Ala Arg Glu Gly Asn Leu Pro 
545                 550         


<210>  1363
<211>  674
<212>  PRT
<213>  Homo Sapiens

<400>  1363

Phe Lys Ile Glu Thr Thr Pro Glu Ser Arg Tyr Leu Ala Gln Ile Gly 
1               5                   10                  15      


Asp Ser Val Ser Leu Thr Cys Ser Thr Thr Gly Cys Glu Ser Pro Phe 
            20                  25                  30          


Phe Ser Trp Arg Thr Gln Ile Asp Ser Pro Leu Asn Gly Lys Val Thr 
        35                  40                  45              


Asn Glu Gly Thr Thr Ser Thr Leu Thr Met Asn Pro Val Ser Phe Gly 
    50                  55                  60                  


Asn Glu His Ser Tyr Leu Cys Thr Ala Thr Cys Glu Ser Arg Lys Leu 
65                  70                  75                  80  


Glu Lys Gly Ile Gln Val Glu Ile Tyr Ser Phe Pro Lys Asp Pro Glu 
                85                  90                  95      


Ile His Leu Ser Gly Pro Leu Glu Ala Gly Lys Pro Ile Thr Val Lys 
            100                 105                 110         


Cys Ser Val Ala Asp Val Tyr Pro Phe Asp Arg Leu Glu Ile Asp Leu 
        115                 120                 125             


Leu Lys Gly Asp His Leu Met Lys Ser Gln Glu Phe Leu Glu Asp Ala 
    130                 135                 140                 


Asp Arg Lys Ser Leu Glu Thr Lys Ser Leu Glu Val Thr Phe Thr Pro 
145                 150                 155                 160 


Val Ile Glu Asp Ile Gly Lys Val Leu Val Cys Arg Ala Lys Leu His 
                165                 170                 175     


Ile Asp Glu Met Asp Ser Val Pro Thr Val Arg Gln Ala Val Lys Glu 
            180                 185                 190         


Leu Gln Val Tyr Ile Ser Pro Lys Asn Thr Val Ile Ser Val Asn Pro 
        195                 200                 205             


Ser Thr Lys Leu Gln Glu Gly Gly Ser Val Thr Met Thr Cys Ser Ser 
    210                 215                 220                 


Glu Gly Leu Pro Ala Pro Glu Ile Phe Trp Ser Lys Lys Leu Asp Asn 
225                 230                 235                 240 


Gly Asn Leu Gln His Leu Ser Gly Asn Ala Thr Leu Thr Leu Ile Ala 
                245                 250                 255     


Met Arg Met Glu Asp Ser Gly Ile Tyr Val Cys Glu Gly Val Asn Leu 
            260                 265                 270         


Ile Gly Lys Asn Arg Lys Glu Val Glu Leu Ile Val Gln Glu Lys Pro 
        275                 280                 285             


Phe Thr Val Glu Ile Ser Pro Gly Pro Arg Ile Ala Ala Gln Ile Gly 
    290                 295                 300                 


Asp Ser Val Met Leu Thr Cys Ser Val Met Gly Cys Glu Ser Pro Ser 
305                 310                 315                 320 


Phe Ser Trp Arg Thr Gln Ile Asp Ser Pro Leu Ser Gly Lys Val Arg 
                325                 330                 335     


Ser Glu Gly Thr Asn Ser Thr Leu Thr Leu Ser Pro Val Ser Phe Glu 
            340                 345                 350         


Asn Glu His Ser Tyr Leu Cys Thr Val Thr Cys Gly His Lys Lys Leu 
        355                 360                 365             


Glu Lys Gly Ile Gln Val Glu Leu Tyr Ser Phe Pro Arg Asp Pro Glu 
    370                 375                 380                 


Ile Glu Met Ser Gly Gly Leu Val Asn Gly Ser Ser Val Thr Val Ser 
385                 390                 395                 400 


Cys Lys Val Pro Ser Val Tyr Pro Leu Asp Arg Leu Glu Ile Glu Leu 
                405                 410                 415     


Leu Lys Gly Glu Thr Ile Leu Glu Asn Ile Glu Phe Leu Glu Asp Thr 
            420                 425                 430         


Asp Met Lys Ser Leu Glu Asn Lys Ser Leu Glu Met Thr Phe Ile Pro 
        435                 440                 445             


Thr Ile Glu Asp Thr Gly Lys Ala Leu Val Cys Gln Ala Lys Leu His 
    450                 455                 460                 


Ile Asp Asp Met Glu Phe Glu Pro Lys Gln Arg Gln Ser Thr Gln Thr 
465                 470                 475                 480 


Leu Tyr Val Asn Val Ala Pro Arg Asp Thr Thr Val Leu Val Ser Pro 
                485                 490                 495     


Ser Ser Ile Leu Glu Glu Gly Ser Ser Val Asn Met Thr Cys Leu Ser 
            500                 505                 510         


Gln Gly Phe Pro Ala Pro Lys Ile Leu Trp Ser Arg Gln Leu Pro Asn 
        515                 520                 525             


Gly Glu Leu Gln Pro Leu Ser Glu Asn Ala Thr Leu Thr Leu Ile Ser 
    530                 535                 540                 


Thr Lys Met Glu Asp Ser Gly Val Tyr Leu Cys Glu Gly Ile Asn Gln 
545                 550                 555                 560 


Ala Gly Arg Ser Arg Lys Glu Val Glu Leu Ile Ile Gln Val Thr Pro 
                565                 570                 575     


Lys Asp Ile Lys Leu Thr Ala Phe Pro Ser Glu Ser Val Lys Glu Gly 
            580                 585                 590         


Asp Thr Val Ile Ile Ser Cys Thr Cys Gly Asn Val Pro Glu Thr Trp 
        595                 600                 605             


Ile Ile Leu Lys Lys Lys Ala Glu Thr Gly Asp Thr Val Leu Lys Ser 
    610                 615                 620                 


Ile Asp Gly Ala Tyr Thr Ile Arg Lys Ala Gln Leu Lys Asp Ala Gly 
625                 630                 635                 640 


Val Tyr Glu Cys Glu Ser Lys Asn Lys Val Gly Ser Gln Leu Arg Ser 
                645                 650                 655     


Leu Thr Leu Asp Val Gln Gly Arg Glu Asn Asn Lys Asp Tyr Phe Ser 
            660                 665                 670         


Pro Glu 
        


<210>  1364
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1364

Ala Pro Met Ala Glu Gly Gly Gly Gln Asn His His Glu Val Val Lys 
1               5                   10                  15      


Phe Met Asp Val Tyr Gln Arg Ser Tyr Cys His Pro Ile Glu Thr Leu 
            20                  25                  30          


Val Asp Ile Phe Gln Glu Tyr Pro Asp Glu Ile Glu Tyr Ile Phe Lys 
        35                  40                  45              


Pro Ser Cys Val Pro Leu Met Arg Cys Gly Gly Cys Cys Asn Asp Glu 
    50                  55                  60                  


Gly Leu Glu Cys Val Pro Thr Glu Glu Ser Asn Ile Thr Met Gln Ile 
65                  70                  75                  80  


Met Arg Ile Lys Pro His Gln Gly Gln His Ile Gly Glu Met Ser Phe 
                85                  90                  95      


Leu Gln His Asn Lys Cys Glu Cys Arg Pro Lys Lys Asp Arg Ala Arg 
            100                 105                 110         


Gln Glu Lys Cys Asp Lys Pro Arg Arg 
        115                 120     


<210>  1365
<211>  186
<212>  PRT
<213>  Homo Sapiens

<400>  1365

Pro Val Ser Gln Pro Asp Ala Pro Gly His Gln Arg Lys Val Val Ser 
1               5                   10                  15      


Trp Ile Asp Val Tyr Thr Arg Ala Thr Cys Gln Pro Arg Glu Val Val 
            20                  25                  30          


Val Pro Leu Thr Val Glu Leu Met Gly Thr Val Ala Lys Gln Leu Val 
        35                  40                  45              


Pro Ser Cys Val Thr Val Gln Arg Cys Gly Gly Cys Cys Pro Asp Asp 
    50                  55                  60                  


Gly Leu Glu Cys Val Pro Thr Gly Gln His Gln Val Arg Met Gln Ile 
65                  70                  75                  80  


Leu Met Ile Arg Tyr Pro Ser Ser Gln Leu Gly Glu Met Ser Leu Glu 
                85                  90                  95      


Glu His Ser Gln Cys Glu Cys Arg Pro Lys Lys Lys Asp Ser Ala Val 
            100                 105                 110         


Lys Pro Asp Arg Ala Ala Thr Pro His His Arg Pro Gln Pro Arg Ser 
        115                 120                 125             


Val Pro Gly Trp Asp Ser Ala Pro Gly Ala Pro Ser Pro Ala Asp Ile 
    130                 135                 140                 


Thr His Pro Thr Pro Ala Pro Gly Pro Ser Ala His Ala Ala Pro Ser 
145                 150                 155                 160 


Thr Thr Ser Ala Leu Thr Pro Gly Pro Ala Ala Ala Ala Ala Asp Ala 
                165                 170                 175     


Ala Ala Ser Ser Val Ala Lys Gly Gly Ala 
            180                 185     


<210>  1366
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  1366

Ala His Tyr Asn Thr Glu Ile Leu Lys Ser Ile Asp Asn Glu Trp Arg 
1               5                   10                  15      


Lys Thr Gln Cys Met Pro Arg Glu Val Cys Ile Asp Val Gly Lys Glu 
            20                  25                  30          


Phe Gly Val Ala Thr Asn Thr Phe Phe Lys Pro Pro Cys Val Ser Val 
        35                  40                  45              


Tyr Arg Cys Gly Gly Cys Cys Asn Ser Glu Gly Leu Gln Cys Met Asn 
    50                  55                  60                  


Thr Ser Thr Ser Tyr Leu Ser Lys Thr Leu Phe Glu Ile Thr Val Pro 
65                  70                  75                  80  


Leu Ser Gln Gly Pro Lys Pro Val Thr Ile Ser Phe Ala Asn His Thr 
                85                  90                  95      


Ser Cys Arg Cys Met Ser Lys Leu Asp Val Tyr Arg Gln Val His Ser 
            100                 105                 110         


Ile Ile Arg Arg 
        115     


<210>  1367
<211>  742
<212>  PRT
<213>  Homo Sapiens

<400>  1367

Gly Arg Lys Ala Lys Cys Glu Pro Ser Gln Phe Gln Cys Thr Asn Gly 
1               5                   10                  15      


Arg Cys Ile Thr Leu Leu Trp Lys Cys Asp Gly Asp Glu Asp Cys Val 
            20                  25                  30          


Asp Gly Ser Asp Glu Lys Asn Cys Val Lys Lys Thr Cys Ala Glu Ser 
        35                  40                  45              


Asp Phe Val Cys Asn Asn Gly Gln Cys Val Pro Ser Arg Trp Lys Cys 
    50                  55                  60                  


Asp Gly Asp Pro Asp Cys Glu Asp Gly Ser Asp Glu Ser Pro Glu Gln 
65                  70                  75                  80  


Cys His Met Arg Thr Cys Arg Ile His Glu Ile Ser Cys Gly Ala His 
                85                  90                  95      


Ser Thr Gln Cys Ile Pro Val Ser Trp Arg Cys Asp Gly Glu Asn Asp 
            100                 105                 110         


Cys Asp Ser Gly Glu Asp Glu Glu Asn Cys Gly Asn Ile Thr Cys Ser 
        115                 120                 125             


Pro Asp Glu Phe Thr Cys Ser Ser Gly Arg Cys Ile Ser Arg Asn Phe 
    130                 135                 140                 


Val Cys Asn Gly Gln Asp Asp Cys Ser Asp Gly Ser Asp Glu Leu Asp 
145                 150                 155                 160 


Cys Ala Pro Pro Thr Cys Gly Ala His Glu Phe Gln Cys Ser Thr Ser 
                165                 170                 175     


Ser Cys Ile Pro Ile Ser Trp Val Cys Asp Asp Asp Ala Asp Cys Ser 
            180                 185                 190         


Asp Gln Ser Asp Glu Ser Leu Glu Gln Cys Gly Arg Gln Pro Val Ile 
        195                 200                 205             


His Thr Lys Cys Pro Ala Ser Glu Ile Gln Cys Gly Ser Gly Glu Cys 
    210                 215                 220                 


Ile His Lys Lys Trp Arg Cys Asp Gly Asp Pro Asp Cys Lys Asp Gly 
225                 230                 235                 240 


Ser Asp Glu Val Asn Cys Pro Ser Arg Thr Cys Arg Pro Asp Gln Phe 
                245                 250                 255     


Glu Cys Glu Asp Gly Ser Cys Ile His Gly Ser Arg Gln Cys Asn Gly 
            260                 265                 270         


Ile Arg Asp Cys Val Asp Gly Ser Asp Glu Val Asn Cys Lys Asn Val 
        275                 280                 285             


Asn Gln Cys Leu Gly Pro Gly Lys Phe Lys Cys Arg Ser Gly Glu Cys 
    290                 295                 300                 


Ile Asp Ile Ser Lys Val Cys Asn Gln Glu Gln Asp Cys Arg Asp Trp 
305                 310                 315                 320 


Ser Asp Glu Pro Leu Lys Glu Cys His Ile Asn Glu Cys Leu Val Asn 
                325                 330                 335     


Asn Gly Gly Cys Ser His Ile Cys Lys Asp Leu Val Ile Gly Tyr Glu 
            340                 345                 350         


Cys Asp Cys Ala Ala Gly Phe Glu Leu Ile Asp Arg Lys Thr Cys Gly 
        355                 360                 365             


Asp Ile Asp Glu Cys Gln Asn Pro Gly Ile Cys Ser Gln Ile Cys Ile 
    370                 375                 380                 


Asn Leu Lys Gly Gly Tyr Lys Cys Glu Cys Ser Arg Gly Tyr Gln Met 
385                 390                 395                 400 


Asp Leu Ala Thr Gly Val Cys Lys Ala Val Gly Lys Glu Pro Ser Leu 
                405                 410                 415     


Ile Phe Thr Asn Arg Arg Asp Ile Arg Lys Ile Gly Leu Glu Arg Lys 
            420                 425                 430         


Glu Tyr Ile Gln Leu Val Glu Gln Leu Arg Asn Thr Val Ala Leu Asp 
        435                 440                 445             


Ala Asp Ile Ala Ala Gln Lys Leu Phe Trp Ala Asp Leu Ser Gln Lys 
    450                 455                 460                 


Ala Ile Phe Ser Ala Ser Ile Asp Asp Lys Val Gly Arg His Val Lys 
465                 470                 475                 480 


Met Ile Asp Asn Val Tyr Asn Pro Ala Ala Ile Ala Val Asp Trp Val 
                485                 490                 495     


Tyr Lys Thr Ile Tyr Trp Thr Asp Ala Ala Ser Lys Thr Ile Ser Val 
            500                 505                 510         


Ala Thr Leu Asp Gly Thr Lys Arg Lys Phe Leu Phe Asn Ser Asp Leu 
        515                 520                 525             


Arg Glu Pro Ala Ser Ile Ala Val Asp Pro Leu Ser Gly Phe Val Tyr 
    530                 535                 540                 


Trp Ser Asp Trp Gly Glu Pro Ala Lys Ile Glu Lys Ala Gly Met Asn 
545                 550                 555                 560 


Gly Phe Asp Arg Arg Pro Leu Val Thr Ala Asp Ile Gln Trp Pro Asn 
                565                 570                 575     


Gly Ile Thr Leu Asp Leu Ile Lys Ser Arg Leu Tyr Trp Leu Asp Ser 
            580                 585                 590         


Lys Leu His Met Leu Ser Ser Val Asp Leu Asn Gly Gln Asp Arg Arg 
        595                 600                 605             


Ile Val Leu Lys Ser Leu Glu Phe Leu Ala His Pro Leu Ala Leu Thr 
    610                 615                 620                 


Ile Phe Glu Asp Arg Val Tyr Trp Ile Asp Gly Glu Asn Glu Ala Val 
625                 630                 635                 640 


Tyr Gly Ala Asn Lys Phe Thr Gly Ser Glu Leu Ala Thr Leu Val Asn 
                645                 650                 655     


Asn Leu Asn Asp Ala Gln Asp Ile Ile Val Tyr His Glu Leu Val Gln 
            660                 665                 670         


Pro Ser Gly Lys Asn Trp Cys Glu Glu Asp Met Glu Asn Gly Gly Cys 
        675                 680                 685             


Glu Tyr Leu Cys Leu Pro Ala Pro Gln Ile Asn Asp His Ser Pro Lys 
    690                 695                 700                 


Tyr Thr Cys Ser Cys Pro Ser Gly Tyr Asn Val Glu Glu Asn Gly Arg 
705                 710                 715                 720 


Asp Cys Gln Arg Ile Asn Val Thr Thr Ala Val Ser Glu Val Ser Val 
                725                 730                 735     


Pro Pro Lys Gly Thr Ser 
            740         


<210>  1368
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  1368

Val Gln Val Thr Ile Pro Asp Gly Phe Val Asn Val Thr Val Gly Ser 
1               5                   10                  15      


Asn Val Thr Leu Ile Cys Ile Tyr Thr Thr Thr Val Ala Ser Arg Glu 
            20                  25                  30          


Gln Leu Ser Ile Gln Trp Ser Phe Phe His Lys Lys Glu Met Glu Pro 
        35                  40                  45              


Ile Ser Ile Tyr Phe Ser Gln Gly Gly Gln Ala Val Ala Ile Gly Gln 
    50                  55                  60                  


Phe Lys Asp Arg Ile Thr Gly Ser Asn Asp Pro Gly Asn Ala Ser Ile 
65                  70                  75                  80  


Thr Ile Ser His Met Gln Pro Ala Asp Ser Gly Ile Tyr Ile Cys Asp 
                85                  90                  95      


Val Asn Asn Pro Pro Asp Phe Leu Gly Gln Asn Gln Gly Ile Leu Asn 
            100                 105                 110         


Val Ser Val Leu Val Lys Pro Ser Lys Pro Leu Cys Ser Val Gln Gly 
        115                 120                 125             


Arg Pro Glu Thr Gly His Thr Ile Ser Leu Ser Cys Leu Ser Ala Leu 
    130                 135                 140                 


Gly Thr Pro Ser Pro Val Tyr Tyr Trp His Lys Leu Glu Gly Arg Asp 
145                 150                 155                 160 


Ile Val Pro Val Lys Glu Asn Phe Asn Pro Thr Thr Gly Ile Leu Val 
                165                 170                 175     


Ile Gly Asn Leu Thr Asn Phe Glu Gln Gly Tyr Tyr Gln Cys Thr Ala 
            180                 185                 190         


Ile Asn Arg Leu Gly Asn Ser Ser Cys Glu Ile Asp Leu Thr Ser Ser 
        195                 200                 205             


His Pro Glu 
    210     


<210>  1369
<211>  383
<212>  PRT
<213>  Homo Sapiens

<400>  1369

Val Val Ile Gly Glu Val His Glu Asn Val Thr Leu His Cys Gly Asn 
1               5                   10                  15      


Ile Ser Gly Leu Arg Gly Gln Val Thr Trp Tyr Arg Asn Asn Ser Glu 
            20                  25                  30          


Pro Val Phe Leu Leu Ser Ser Asn Ser Ser Leu Arg Pro Ala Glu Pro 
        35                  40                  45              


Arg Phe Ser Leu Val Asp Ala Thr Ser Leu His Ile Glu Ser Leu Ser 
    50                  55                  60                  


Leu Gly Asp Glu Gly Ile Tyr Thr Cys Gln Glu Ile Leu Asn Val Thr 
65                  70                  75                  80  


Gln Trp Phe Gln Val Trp Leu Gln Val Ala Ser Gly Pro Tyr Gln Ile 
                85                  90                  95      


Glu Val His Ile Val Ala Thr Gly Thr Leu Pro Asn Gly Thr Leu Tyr 
            100                 105                 110         


Ala Ala Arg Gly Ser Gln Val Asp Phe Ser Cys Asn Ser Ser Ser Arg 
        115                 120                 125             


Pro Pro Pro Val Val Glu Trp Trp Phe Gln Ala Leu Asn Ser Ser Ser 
    130                 135                 140                 


Glu Ser Phe Gly His Asn Leu Thr Val Asn Phe Phe Ser Leu Leu Leu 
145                 150                 155                 160 


Ile Ser Pro Asn Leu Gln Gly Asn Tyr Thr Cys Leu Ala Leu Asn Gln 
                165                 170                 175     


Leu Ser Lys Arg His Arg Lys Val Thr Thr Glu Leu Leu Val Tyr Tyr 
            180                 185                 190         


Pro Pro Pro Ser Ala Pro Gln Cys Trp Ala Gln Met Ala Ser Gly Ser 
        195                 200                 205             


Phe Met Leu Gln Leu Thr Cys Arg Trp Asp Gly Gly Tyr Pro Asp Pro 
    210                 215                 220                 


Asp Phe Leu Trp Ile Glu Glu Pro Gly Gly Val Ile Val Gly Lys Ser 
225                 230                 235                 240 


Lys Leu Gly Val Glu Met Leu Ser Glu Ser Gln Leu Ser Asp Gly Lys 
                245                 250                 255     


Lys Phe Lys Cys Val Thr Ser His Ile Val Gly Pro Glu Ser Gly Ala 
            260                 265                 270         


Ser Cys Met Val Gln Ile Arg Gly Pro Ser Leu Leu Ser Glu Pro Met 
        275                 280                 285             


Lys Thr Cys Phe Thr Gly Gly Asn Val Thr Leu Thr Cys Gln Val Ser 
    290                 295                 300                 


Gly Ala Tyr Pro Pro Ala Lys Ile Leu Trp Leu Arg Asn Leu Thr Gln 
305                 310                 315                 320 


Pro Glu Val Ile Ile Gln Pro Ser Ser Arg His Leu Ile Thr Gln Asp 
                325                 330                 335     


Gly Gln Asn Ser Thr Leu Thr Ile His Asn Cys Ser Gln Asp Leu Asp 
            340                 345                 350         


Glu Gly Tyr Tyr Ile Cys Arg Ala Asp Ser Pro Val Gly Val Arg Glu 
        355                 360                 365             


Met Glu Ile Trp Leu Ser Val Lys Glu Pro Leu Asn Ile Gly Gly 
    370                 375                 380             


<210>  1370
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  1370

Val Glu Val Lys Val Pro Thr Glu Pro Leu Ser Thr Pro Leu Gly Lys 
1               5                   10                  15      


Thr Ala Glu Leu Thr Cys Thr Tyr Ser Thr Ser Val Gly Asp Ser Phe 
            20                  25                  30          


Ala Leu Glu Trp Ser Phe Val Gln Pro Gly Lys Pro Ile Ser Glu Ser 
        35                  40                  45              


His Pro Ile Leu Tyr Phe Thr Asn Gly His Leu Tyr Pro Thr Gly Ser 
    50                  55                  60                  


Lys Ser Lys Arg Val Ser Leu Leu Gln Asn Pro Pro Thr Val Gly Val 
65                  70                  75                  80  


Ala Thr Leu Lys Leu Thr Asp Val His Pro Ser Asp Thr Gly Thr Tyr 
                85                  90                  95      


Leu Cys Gln Val Asn Asn Pro Pro Asp Phe Tyr Thr Asn Gly Leu Gly 
            100                 105                 110         


Leu Ile Asn Leu Thr Val Leu Val Pro Pro Ser Asn Pro Leu Cys Ser 
        115                 120                 125             


Gln Ser Gly Gln Thr Ser Val Gly Gly Ser Thr Ala Leu Arg Cys Ser 
    130                 135                 140                 


Ser Ser Glu Gly Ala Pro Lys Pro Val Tyr Asn Trp Val Arg Leu Gly 
145                 150                 155                 160 


Thr Phe Pro Thr Pro Ser Pro Gly Ser Met Val Gln Asp Glu Val Ser 
                165                 170                 175     


Gly Gln Leu Ile Leu Thr Asn Leu Ser Leu Thr Ser Ser Gly Thr Tyr 
            180                 185                 190         


Arg Cys Val Ala Thr Asn Gln Met Gly Ser Ala Ser Cys Glu Leu Thr 
        195                 200                 205             


Leu Ser Val Thr Glu Pro Ser Gln Gly Arg Val Ala 
    210                 215                 220 


<210>  1371
<211>  264
<212>  PRT
<213>  Homo Sapiens

<400>  1371

Arg Pro Ile Leu Glu Val Pro Glu Ser Val Thr Gly Pro Trp Lys Gly 
1               5                   10                  15      


Asp Val Asn Leu Pro Cys Thr Tyr Asp Pro Leu Gln Gly Tyr Thr Gln 
            20                  25                  30          


Val Leu Val Lys Trp Leu Val Gln Arg Gly Ser Asp Pro Val Thr Ile 
        35                  40                  45              


Phe Leu Arg Asp Ser Ser Gly Asp His Ile Gln Gln Ala Lys Tyr Gln 
    50                  55                  60                  


Gly Arg Leu His Val Ser His Lys Val Pro Gly Asp Val Ser Leu Gln 
65                  70                  75                  80  


Leu Ser Thr Leu Glu Met Asp Asp Arg Ser His Tyr Thr Cys Glu Val 
                85                  90                  95      


Thr Trp Gln Thr Pro Asp Gly Asn Gln Val Val Arg Asp Lys Ile Thr 
            100                 105                 110         


Glu Leu Arg Val Gln Lys Leu Ser Val Ser Lys Pro Thr Val Thr Thr 
        115                 120                 125             


Gly Ser Gly Tyr Gly Phe Thr Val Pro Gln Gly Met Arg Ile Ser Leu 
    130                 135                 140                 


Gln Cys Gln Ala Arg Gly Ser Pro Pro Ile Ser Tyr Ile Trp Tyr Lys 
145                 150                 155                 160 


Gln Gln Thr Asn Asn Gln Glu Pro Ile Lys Val Ala Thr Leu Ser Thr 
                165                 170                 175     


Leu Leu Phe Lys Pro Ala Val Ile Ala Asp Ser Gly Ser Tyr Phe Cys 
            180                 185                 190         


Thr Ala Lys Gly Gln Val Gly Ser Glu Gln His Ser Asp Ile Val Lys 
        195                 200                 205             


Phe Val Val Lys Asp Ser Ser Lys Leu Leu Lys Thr Lys Thr Glu Ala 
    210                 215                 220                 


Pro Thr Thr Met Thr Tyr Pro Leu Lys Ala Thr Ser Thr Val Lys Gln 
225                 230                 235                 240 


Ser Trp Asp Trp Thr Thr Asp Met Asp Gly Tyr Leu Gly Glu Thr Ser 
                245                 250                 255     


Ala Gly Pro Gly Lys Ser Leu Pro 
            260                 


<210>  1372
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  1372

Val Arg Ile Asn Gly Asp Gly Gln Glu Val Leu Tyr Leu Ala Glu Gly 
1               5                   10                  15      


Asp Asn Val Arg Leu Gly Cys Pro Tyr Val Leu Asp Pro Glu Asp Tyr 
            20                  25                  30          


Gly Pro Asn Gly Leu Asp Ile Glu Trp Met Gln Val Asn Ser Asp Pro 
        35                  40                  45              


Ala His His Arg Glu Asn Val Phe Leu Ser Tyr Gln Asp Lys Arg Ile 
    50                  55                  60                  


Asn His Gly Ser Leu Pro His Leu Gln Gln Arg Val Arg Phe Ala Ala 
65                  70                  75                  80  


Ser Asp Pro Ser Gln Tyr Asp Ala Ser Ile Asn Leu Met Asn Leu Gln 
                85                  90                  95      


Val Ser Asp Thr Ala Thr Tyr Glu Cys Arg Val Lys Lys Thr Thr Met 
            100                 105                 110         


Ala Thr Arg Lys Val Ile Val Thr Val Gln Ala Arg Pro Ala Val Pro 
        115                 120                 125             


Met Cys Trp Thr Glu Gly His Met Thr Tyr Gly Asn Asp Val Val Leu 
    130                 135                 140                 


Lys Cys Tyr Ala Ser Gly Gly Ser Gln Pro Leu Ser Tyr Lys Trp Ala 
145                 150                 155                 160 


Lys Ile Ser Gly His His Tyr Pro Tyr Arg Ala Gly Ser Tyr Thr Ser 
                165                 170                 175     


Gln His Ser Tyr His Ser Glu Leu Ser Tyr Gln Glu Ser Phe His Ser 
            180                 185                 190         


Ser Ile Asn Gln Gly Leu Asn Asn Gly Asp Leu Val Leu Lys Asp Ile 
        195                 200                 205             


Ser Arg Ala Asp Asp Gly Leu Tyr Gln Cys Thr Val Ala Asn Asn Val 
    210                 215                 220                 


Gly Tyr Ser Val Cys Val Val Glu Val Lys Val Ser Asp Ser Arg Arg 
225                 230                 235                 240 


Ile Gly 
        


<210>  1373
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1373

Tyr Glu Asp Glu Lys Lys Asn Glu Lys Pro Pro Lys Pro Ser Leu His 
1               5                   10                  15      


Ala Trp Pro Ser Ser Val Val Glu Ala Glu Ser Asn Val Thr Leu Lys 
            20                  25                  30          


Cys Gln Ala His Ser Gln Asn Val Thr Phe Val Leu Arg Lys Val Asn 
        35                  40                  45              


Asp Ser Gly Tyr Lys Gln Glu Gln Ser Ser Ala Glu Asn Glu Ala Glu 
    50                  55                  60                  


Phe Pro Phe Thr Asp Leu Lys Pro Lys Asp Ala Gly Arg Tyr Phe Cys 
65                  70                  75                  80  


Ala Tyr Lys Thr Thr Ala Ser His Glu Trp Ser Glu Ser Ser Glu His 
                85                  90                  95      


Leu Gln Leu Val Val Thr Asp Lys His Asp Glu Leu Glu Ala Pro Ser 
            100                 105                 110         


Met Lys Thr Asp Thr Arg Thr 
        115                 


<210>  1374
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  1374

Ser Ser Gln Ala Lys Phe Thr Glu Phe Pro Arg Asn Val Thr Ala Thr 
1               5                   10                  15      


Glu Gly Gln Asn Val Glu Met Ser Cys Ala Phe Gln Ser Gly Ser Ala 
            20                  25                  30          


Ser Val Tyr Leu Glu Ile Gln Trp Trp Phe Leu Arg Gly Pro Glu Asp 
        35                  40                  45              


Leu Asp Pro Gly Ala Glu Gly Ala Gly Ala Gln Val Lys Leu Leu Pro 
    50                  55                  60                  


Asp Arg Asp Pro Asp Ser Asp Gly Thr Lys Ile Ser Thr Val Lys Val 
65                  70                  75                  80  


Gln Gly Asn Asp Ile Ser His Lys Leu Gln Ile Ser Lys Val Arg Lys 
                85                  90                  95      


Lys Asp Glu Gly Leu Tyr Glu Cys Arg Val Thr Asp Ala Asn Tyr Gly 
            100                 105                 110         


Glu Leu Gln Glu His Lys Ala Gln Ala Tyr Leu Lys Val Asn Ala Asn 
        115                 120                 125             


Ser His Ala Arg Arg Met Gln Ala Phe Glu Ala Ser Pro Met Trp Leu 
    130                 135                 140                 


Gln Asp Met Lys Pro Arg Lys Asn Val Ser Ala Ala Ile Pro Ser Ser 
145                 150                 155                 160 


Ile His Gly Ser Ala Asn Gln Arg Thr His Ser Thr Ser Ser Pro Gln 
                165                 170                 175     


Val Val Ala Lys Ile Pro Lys Gln Ser Pro Gln Ser Gly Met Glu Thr 
            180                 185                 190         


His Phe Glu Pro Phe Ile Leu Pro Leu Thr Asn Ala Pro Gln Lys Gly 
        195                 200                 205             


Gln Ser Tyr Arg Val Asp Arg Phe Met Asn Gly Asp Phe 
    210                 215                 220     


<210>  1375
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1375

Ala Phe Thr Glu Val Pro Lys Asp Val Thr Val Arg Glu Gly Asp Asp 
1               5                   10                  15      


Ile Glu Met Pro Cys Ala Phe Arg Ala Ser Gly Ala Thr Ser Tyr Ser 
            20                  25                  30          


Leu Glu Ile Gln Trp Trp Tyr Leu Lys Glu Pro Pro Arg Glu Leu Leu 
        35                  40                  45              


His Glu Leu Ala Leu Ser Val Pro Gly Ala Arg Ser Lys Val Thr Asn 
    50                  55                  60                  


Lys Asp Ala Thr Lys Ile Ser Thr Val Arg Val Gln Gly Asn Asp Ile 
65                  70                  75                  80  


Ser His Arg Leu Arg Leu Ser Ala Val Arg Leu Gln Asp Glu Gly Val 
                85                  90                  95      


Tyr Glu Cys Arg Val Ser Asp Tyr Ser Asp Asp Asp Thr Gln Glu His 
            100                 105                 110         


Lys Ala Gln Ala Met Leu Arg Val Leu Ser Arg Phe Ala Pro Pro Asn 
        115                 120                 125             


Met Gln Ala Ala Glu Ala Val Ser His Ile Gln Ser Ser Gly Pro Arg 
    130                 135                 140                 


Arg His Gly Pro Ala Ser Ala Ala Asn Ala Asn Asn Ala Gly Ala Ala 
145                 150                 155                 160 


Ser Arg Thr Thr Ser Glu Pro Gly Arg Gly Asp Lys Ser Pro Pro Pro 
                165                 170                 175     


Gly Ser Pro Pro Ala Ala Ile Asp Pro Ala Val Pro Glu Ala Ala Ala 
            180                 185                 190         


Ala Ser Ala Ala His Thr Pro Thr Thr Thr Val Ala Ala Ala Ala Ala 
        195                 200                 205             


Ala Ser Ser Ala Ser Pro Pro Ser Gly Gln Ala Val Leu Leu Arg Gln 
    210                 215                 220                 


Arg His Gly Ser Gly Thr Gly Arg Ser Tyr Thr 
225                 230                 235 


<210>  1376
<211>  180
<212>  PRT
<213>  Homo Sapiens

<400>  1376

Thr Arg Pro Ala Gly His Ala Pro Trp Asp Asn His Val Ser Gly His 
1               5                   10                  15      


Ala Leu Phe Thr Glu Thr Pro His Asp Met Thr Ala Arg Thr Gly Glu 
            20                  25                  30          


Asp Val Glu Met Ala Cys Ser Phe Arg Gly Ser Gly Ser Pro Ser Tyr 
        35                  40                  45              


Ser Leu Glu Ile Gln Trp Trp Tyr Val Arg Ser His Arg Asp Trp Thr 
    50                  55                  60                  


Asp Lys Gln Ala Trp Ala Ser Asn Gln Leu Lys Ala Ser Gln Gln Glu 
65                  70                  75                  80  


Asp Ala Gly Lys Glu Ala Thr Lys Ile Ser Val Val Lys Val Val Gly 
                85                  90                  95      


Ser Asn Ile Ser His Lys Leu Arg Leu Ser Arg Val Lys Pro Thr Asp 
            100                 105                 110         


Glu Gly Ser Tyr Glu Cys Arg Val Ile Asp Phe Ser Asp Gly Lys Ala 
        115                 120                 125             


Arg His His Lys Val Lys Ala Tyr Leu Arg Val Gln Pro Gly Glu Asn 
    130                 135                 140                 


Ser Val Leu His Leu Pro Glu Ala Pro Pro Ala Ala Pro Ala Pro Pro 
145                 150                 155                 160 


Pro Pro Lys Pro Gly Lys Glu Leu Arg Lys Arg Ser Val Asp Gln Glu 
                165                 170                 175     


Ala Cys Ser Leu 
            180 


<210>  1377
<211>  157
<212>  PRT
<213>  Homo Sapiens

<400>  1377

Leu Asn Val Thr Val Ser Pro Gly Pro Val Val Asp Tyr Leu Glu Gly 
1               5                   10                  15      


Glu Asn Ala Thr Leu Leu Cys His Val Ser Gln Lys Arg Arg Lys Asp 
            20                  25                  30          


Ser Leu Leu Ala Val Arg Trp Phe Phe Ala His Ser Ser Asp Ser Gln 
        35                  40                  45              


Glu Ala Leu Met Val Lys Met Thr Lys Leu Arg Val Val Gln Tyr Tyr 
    50                  55                  60                  


Gly Asn Phe Ser Arg Ser Ala Lys Arg Arg Arg Leu Arg Leu Leu Glu 
65                  70                  75                  80  


Glu Gln Arg Gly Ala Leu Tyr Arg Leu Ser Val Leu Thr Leu Gln Pro 
                85                  90                  95      


Ser Asp Gln Gly His Tyr Val Cys Arg Val Gln Glu Ile Ser Arg His 
            100                 105                 110         


Arg Asn Lys Trp Thr Ala Trp Ser Asn Gly Ser Ser Ala Thr Glu Met 
        115                 120                 125             


Arg Val Ile Ser Leu Lys Ala Ser Glu Glu Ser Ser Phe Glu Lys Thr 
    130                 135                 140                 


Lys Glu Thr Trp Ala Phe Phe Glu Asp Leu Tyr Val Tyr 
145                 150                 155         


<210>  1378
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1378

Leu Gln Ser Gln Gly Val Ser Leu Tyr Ile Pro Gln Ala Thr Ile Asn 
1               5                   10                  15      


Ala Thr Val Lys Glu Asp Ile Leu Leu Ser Val Glu Tyr Ser Cys His 
            20                  25                  30          


Gly Val Pro Thr Ile Glu Trp Thr Tyr Ser Ser Asn Trp Gly Thr Gln 
        35                  40                  45              


Lys Ile Val Glu Trp Lys Pro Gly Thr Gln Ala Asn Ile Ser Gln Ser 
    50                  55                  60                  


His Lys Asp Arg Val Cys Thr Phe Asp Asn Gly Ser Ile Gln Leu Phe 
65                  70                  75                  80  


Ser Val Gly Val Arg Asp Ser Gly Tyr Tyr Val Ile Thr Val Thr Glu 
                85                  90                  95      


Arg Leu Gly Ser Ser Gln Phe Gly Thr Ile Val Leu His Val Ser Glu 
            100                 105                 110         


Ile Leu Tyr Glu Asp Leu His 
        115                 


<210>  1379
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1379

Leu Ile Ile Gly Phe Gly Ile Ser Gly Arg His Ser Ile Thr Val Thr 
1               5                   10                  15      


Thr Val Ala Ser Ala Gly Asn Ile Gly Glu Asp Gly Ile Leu Ser Cys 
            20                  25                  30          


Thr Phe Glu Pro Asp Ile Lys Leu Ser Asp Ile Val Ile Gln Trp Leu 
        35                  40                  45              


Lys Glu Gly Val Leu Gly Leu Val His Glu Phe Lys Glu Gly Lys Asp 
    50                  55                  60                  


Glu Leu Ser Glu Gln Asp Glu Met Phe Arg Gly Arg Thr Ala Val Phe 
65                  70                  75                  80  


Ala Asp Gln Val Ile Val Gly Asn Ala Ser Leu Arg Leu Lys Asn Val 
                85                  90                  95      


Gln Leu Thr Asp Ala Gly Thr Tyr Lys Cys Tyr Ile Ile Thr Ser Lys 
            100                 105                 110         


Gly Lys Gly Asn Ala Asn Leu Glu Tyr Lys Thr Gly Ala Phe Ser Met 
        115                 120                 125             


Pro Glu Val Asn Val Asp Tyr Asn Ala Ser Ser Glu Thr Leu Arg Cys 
    130                 135                 140                 


Glu Ala Pro Arg Trp Phe Pro Gln Pro Thr Val Val Trp Ala Ser Gln 
145                 150                 155                 160 


Val Asp Gln Gly Ala Asn Phe Ser Glu Val Ser Asn Thr Ser Phe Glu 
                165                 170                 175     


Leu Asn Ser Glu Asn Val Thr Met Lys Val Val Ser Val Leu Tyr Asn 
            180                 185                 190         


Val Thr Ile Asn Asn Thr Tyr Ser Cys Met Ile Glu Asn Asp Ile Ala 
        195                 200                 205             


Lys Ala Thr Gly Asp Ile Lys Val Thr Glu Ser Glu Ile Lys Arg Arg 
    210                 215                 220                 


Ser His Leu Gln Leu Leu Asn Ser Lys Ala Ser 
225                 230                 235 


<210>  1380
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  1380

Glu Arg Gly Pro Pro Ala Ser Ala Pro Arg Gly Asp Leu Met Phe Leu 
1               5                   10                  15      


Leu Asp Ser Ser Ala Ser Val Ser His Tyr Glu Phe Ser Arg Val Arg 
            20                  25                  30          


Glu Phe Val Gly Gln Leu Val Ala Pro Leu Pro Leu Gly Thr Gly Ala 
        35                  40                  45              


Leu Arg Ala Ser Leu Val His Val Gly Ser Arg Pro Tyr Thr Glu Phe 
    50                  55                  60                  


Pro Phe Gly Gln His Ser Ser Gly Glu Ala Ala Gln Asp Ala Val Arg 
65                  70                  75                  80  


Ala Ser Ala Gln Arg Met Gly Asp Thr His Thr Gly Leu Ala Leu Val 
                85                  90                  95      


Tyr Ala Lys Glu Gln Leu Phe Ala Glu Ala Ser Gly Ala Arg Pro Gly 
            100                 105                 110         


Val Pro Lys Val Leu Val Trp Val Thr Asp Gly Gly Ser Ser Asp Pro 
        115                 120                 125             


Val Gly Pro Pro Met Gln Glu Leu Lys Asp Leu Gly Val Thr Val Phe 
    130                 135                 140                 


Ile Val Ser Thr Gly Arg Gly Asn Phe Leu Glu Leu Ser Ala Ala Ala 
145                 150                 155                 160 


Ser Ala Pro Ala Glu Lys His Leu His Phe Val Asp Val Asp Asp Leu 
                165                 170                 175     


His Ile Ile Val Gln Glu Leu Arg Gly Ser Ile Leu Asp Ala Met Arg 
            180                 185                 190         


Pro Gln Gln Leu His Ala Thr Glu Ile Thr Ser Ser Gly Phe Arg Leu 
        195                 200                 205             


Ala Trp Pro Pro Leu Leu Thr Ala Asp Ser Gly Tyr Tyr Val Leu Glu 
    210                 215                 220                 


Leu Val Pro Ser Ala Gln Pro Gly Ala Ala Arg Arg Gln Gln Leu Pro 
225                 230                 235                 240 


Gly Asn Ala Thr Asp Trp Ile Trp Ala Gly Leu Asp Pro Asp Thr Asp 
                245                 250                 255     


Tyr Asp Val Ala Leu Val Pro Glu Ser Asn Val Arg Leu Leu Arg Pro 
            260                 265                 270         


Gln Ile Leu Arg Val Arg Thr Arg Pro Gly Glu Ala Gly Pro Gly Ala 
        275                 280                 285             


Ser Gly Pro Glu Ser Gly Ala Gly Pro Ala Pro Thr Gln Leu Ala Ala 
    290                 295                 300                 


Leu Pro Ala Pro Glu Glu Ala Gly Pro Glu Arg Ile Val Ile Ser His 
305                 310                 315                 320 


Ala Arg Pro Arg Ser Leu Arg Val Ser Trp Ala Pro Ala Leu Gly Ser 
                325                 330                 335     


Ala Ala Ala Leu Gly Tyr His Val Gln Phe Gly Pro Leu Arg Gly Gly 
            340                 345                 350         


Glu Ala Gln Arg Val Glu Val Pro Ala Gly Arg Asn Cys Thr Thr Leu 
        355                 360                 365             


Gln Gly Leu Ala Pro Gly Thr Ala Tyr Leu Val Thr Val Thr Ala Ala 
    370                 375                 380                 


Phe Arg Ser Gly Arg Glu Ser Ala Leu Ser Ala Lys Ala Cys Thr Pro 
385                 390                 395                 400 


Asp Gly Pro Arg Pro Arg Pro Arg Pro Val Pro Arg Ala Pro Thr Pro 
                405                 410                 415     


Gly Thr Ala Ser Arg Glu Pro 
            420             


<210>  1381
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  1381

Met Glu Ala His Val Phe Gln Lys Asp Trp Thr Ala Thr Ser Ala Ser 
1               5                   10                  15      


Ala Arg Trp Pro Leu Glu Gly Arg Leu Thr Val Val Ala Leu Lys Leu 
            20                  25                  30          


Ser Leu Glu Cys Arg Val Asp Leu Leu Phe Leu Leu Asp Ser Ser Ala 
        35                  40                  45              


Gly Thr Thr Leu Asp Gly Phe Leu Arg Ala Lys Val Phe Val Lys Arg 
    50                  55                  60                  


Phe Val Arg Ala Val Leu Ser Glu Asp Ser Arg Ala Arg Val Gly Val 
65                  70                  75                  80  


Ala Thr Tyr Ser Arg Glu Leu Leu Val Ala Val Pro Val Gly Glu Tyr 
                85                  90                  95      


Gln Asp Val Pro Asp Leu Val Trp Ser Leu Asp Gly Ile Pro Phe Arg 
            100                 105                 110         


Gly Gly Pro Thr Leu Thr Gly Ser Ala Leu Arg Gln Ala Ala Glu Arg 
        115                 120                 125             


Gly Phe Gly Ser Ala Thr Arg Thr Gly Gln Asp Arg Pro Arg Arg Val 
    130                 135                 140                 


Val Val Leu Leu Thr Glu Ser His Ser Glu Asp Glu Val Ala Gly Pro 
145                 150                 155                 160 


Ala Arg His Ala Arg Ala Arg Glu Leu Leu Leu Leu Gly Val Gly Ser 
                165                 170                 175     


Glu Ala Val Arg Ala Glu Leu Glu Glu Ile Thr Gly Ser Pro Lys His 
            180                 185                 190         


Val Met Val Tyr Ser Asp Pro Gln Asp Leu Phe Asn Gln Ile Pro Glu 
        195                 200                 205             


Leu Gln Gly Lys Leu Cys Ser Arg Gln Arg Pro Gly Cys Arg Thr Gln 
    210                 215                 220                 


Ala Leu Asp Leu Val Phe Met Leu Asp Thr Ser Ala Ser Val Gly Pro 
225                 230                 235                 240 


Glu Asn Phe Ala Gln Met Gln Ser Phe Val Arg Ser Cys Ala Leu Gln 
                245                 250                 255     


Phe Glu Val Asn Pro Asp Val Thr Gln Val Gly Leu Val Val Tyr Gly 
            260                 265                 270         


Ser Gln Val Gln Thr Ala Phe Gly Leu Asp Thr Lys Pro Thr Arg Ala 
        275                 280                 285             


Ala Met Leu Arg Ala Ile Ser Gln Ala Pro Tyr Leu Gly Gly Val Gly 
    290                 295                 300                 


Ser Ala Gly Thr Ala Leu Leu His Ile Tyr Asp Lys Val Met Thr Val 
305                 310                 315                 320 


Gln Arg Gly Ala Arg Pro Gly Val Pro Lys Ala Val Val Val Leu Thr 
                325                 330                 335     


Gly Gly Arg Gly Ala Glu Asp Ala Ala Val Pro Ala Gln Lys Leu Arg 
            340                 345                 350         


Asn Asn Gly Ile Ser Val Leu Val Val Gly Val Gly Pro Val Leu Ser 
        355                 360                 365             


Glu Gly Leu Arg Arg Leu Ala Gly Pro Arg Asp Ser Leu Ile His Val 
    370                 375                 380                 


Ala Ala Tyr Ala Asp Leu Arg Tyr His Gln Asp Val Leu Ile Glu Trp 
385                 390                 395                 400 


Leu Cys Gly Gly Glu Trp Gly Asn Pro His Pro Gln Gly Cys Pro His 
                405                 410                 415     


Gly Arg Pro Ser Ala 
            420     


<210>  1382
<211>  934
<212>  PRT
<213>  Homo Sapiens

<400>  1382

Arg Gly Tyr Thr Gly Arg Lys Pro Pro Gly His Phe Ala Ala Glu Arg 
1               5                   10                  15      


Arg Arg Leu Gly Pro His Val Cys Leu Ser Gly Phe Gly Ser Gly Cys 
            20                  25                  30          


Cys Pro Gly Trp Ala Pro Ser Met Gly Gly Gly His Cys Thr Leu Pro 
        35                  40                  45              


Leu Cys Ser Phe Gly Cys Gly Ser Gly Ile Cys Ile Ala Pro Asn Val 
    50                  55                  60                  


Cys Ser Cys Gln Asp Gly Glu Gln Gly Ala Thr Cys Pro Glu Thr His 
65                  70                  75                  80  


Gly Pro Cys Gly Glu Tyr Gly Cys Asp Leu Thr Cys Asn His Gly Gly 
                85                  90                  95      


Cys Gln Glu Val Ala Arg Val Cys Pro Val Gly Phe Ser Met Thr Glu 
            100                 105                 110         


Thr Ala Val Gly Ile Arg Cys Thr Asp Ile Asp Glu Cys Val Thr Ser 
        115                 120                 125             


Ser Cys Glu Gly His Cys Val Asn Thr Glu Gly Gly Phe Val Cys Glu 
    130                 135                 140                 


Cys Gly Pro Gly Met Gln Leu Ser Ala Asp Arg His Ser Cys Gln Asp 
145                 150                 155                 160 


Thr Asp Glu Cys Leu Gly Thr Pro Cys Gln Gln Arg Cys Lys Asn Ser 
                165                 170                 175     


Ile Gly Ser Tyr Lys Cys Ser Cys Arg Thr Gly Phe His Leu His Gly 
            180                 185                 190         


Asn Arg His Ser Cys Val Asp Val Asn Glu Cys Arg Arg Pro Leu Glu 
        195                 200                 205             


Arg Arg Val Cys His His Ser Cys His Asn Thr Val Gly Ser Phe Leu 
    210                 215                 220                 


Cys Thr Cys Arg Pro Gly Phe Arg Leu Arg Ala Asp Arg Val Ser Cys 
225                 230                 235                 240 


Glu Ala Phe Pro Lys Ala Val Leu Ala Pro Ser Ala Ile Leu Gln Pro 
                245                 250                 255     


Arg Gln His Pro Ser Lys Met Leu Leu Leu Leu Pro Glu Ala Gly Arg 
            260                 265                 270         


Pro Ala Leu Ser Pro Gly His Ser Pro Pro Ser Gly Ala Pro Gly Pro 
        275                 280                 285             


Pro Ala Gly Val Arg Thr Thr Arg Leu Pro Ser Pro Thr Pro Arg Leu 
    290                 295                 300                 


Pro Thr Ser Ser Pro Ser Ala Pro Val Trp Leu Leu Ser Thr Leu Leu 
305                 310                 315                 320 


Ala Thr Pro Val Pro Thr Ala Ser Leu Leu Gly Asn Leu Arg Pro Pro 
                325                 330                 335     


Ser Leu Leu Gln Gly Glu Val Met Gly Thr Pro Ser Ser Pro Arg Gly 
            340                 345                 350         


Pro Glu Ser Pro Arg Leu Ala Ala Gly Pro Ser Pro Cys Trp His Leu 
        355                 360                 365             


Gly Ala Met His Glu Ser Arg Ser Arg Trp Thr Glu Pro Gly Cys Ser 
    370                 375                 380                 


Gln Cys Trp Cys Glu Asp Gly Lys Val Thr Cys Glu Lys Val Arg Cys 
385                 390                 395                 400 


Glu Ala Ala Cys Ser His Pro Ile Pro Ser Arg Asp Gly Gly Cys Cys 
                405                 410                 415     


Pro Ser Cys Thr Gly Cys Phe His Ser Gly Val Val Arg Ala Glu Gly 
            420                 425                 430         


Asp Val Phe Ser Pro Pro Asn Glu Asn Cys Thr Val Cys Val Cys Leu 
        435                 440                 445             


Ala Gly Asn Val Ser Cys Ile Ser Pro Glu Cys Pro Ser Gly Pro Cys 
    450                 455                 460                 


Gln Thr Pro Pro Gln Thr Asp Cys Cys Thr Cys Val Pro Val Arg Cys 
465                 470                 475                 480 


Tyr Phe His Gly Arg Trp Tyr Ala Asp Gly Ala Val Phe Ser Gly Gly 
                485                 490                 495     


Gly Asp Glu Cys Thr Thr Cys Val Cys Gln Asn Gly Glu Val Glu Cys 
            500                 505                 510         


Ser Phe Met Pro Cys Pro Glu Leu Ala Cys Pro Arg Glu Glu Trp Arg 
        515                 520                 525             


Leu Gly Pro Gly Gln Cys Cys Phe Thr Cys Gln Glu Pro Thr Pro Ser 
    530                 535                 540                 


Thr Gly Cys Ser Leu Asp Asp Asn Gly Val Glu Phe Pro Ile Gly Gln 
545                 550                 555                 560 


Ile Trp Ser Pro Gly Asp Pro Cys Glu Leu Cys Ile Cys Gln Ala Asp 
                565                 570                 575     


Gly Ser Val Ser Cys Lys Arg Thr Asp Cys Val Asp Ser Cys Pro His 
            580                 585                 590         


Pro Ile Arg Ile Pro Gly Gln Cys Cys Pro Asp Cys Ser Ala Gly Cys 
        595                 600                 605             


Thr Tyr Thr Gly Arg Ile Phe Tyr Asn Asn Glu Thr Phe Pro Ser Val 
    610                 615                 620                 


Leu Asp Pro Cys Leu Ser Cys Ile Cys Leu Leu Gly Ser Val Ala Cys 
625                 630                 635                 640 


Ser Pro Val Asp Cys Pro Ile Thr Cys Thr Tyr Pro Phe His Pro Asp 
                645                 650                 655     


Gly Glu Cys Cys Pro Val Cys Arg Asp Cys Asn Tyr Glu Gly Arg Lys 
            660                 665                 670         


Val Ala Asn Gly Gln Val Phe Thr Leu Asp Asp Glu Pro Cys Thr Arg 
        675                 680                 685             


Cys Thr Cys Gln Leu Gly Glu Val Ser Cys Glu Lys Val Pro Cys Gln 
    690                 695                 700                 


Arg Ala Cys Ala Asp Pro Ala Leu Leu Pro Gly Asp Cys Cys Ser Ser 
705                 710                 715                 720 


Cys Pro Asp Ser Leu Ser Pro Leu Glu Glu Lys Gln Gly Leu Ser Pro 
                725                 730                 735     


His Gly Asn Val Ala Phe Ser Lys Ala Gly Arg Ser Leu His Gly Asp 
            740                 745                 750         


Thr Glu Ala Pro Val Asn Cys Ser Ser Cys Pro Gly Pro Pro Thr Ala 
        755                 760                 765             


Ser Pro Ser Arg Pro Val Leu His Leu Leu Gln Leu Leu Leu Arg Thr 
    770                 775                 780                 


Asn Leu Met Lys Thr Gln Thr Leu Pro Thr Ser Pro Ala Gly Ala His 
785                 790                 795                 800 


Gly Pro His Ser Leu Ala Leu Gly Leu Thr Ala Thr Phe Pro Gly Glu 
                805                 810                 815     


Pro Gly Ala Ser Pro Arg Leu Ser Pro Gly Pro Ser Thr Pro Pro Gly 
            820                 825                 830         


Ala Pro Thr Leu Pro Leu Ala Ser Pro Gly Ala Pro Gln Pro Pro Pro 
        835                 840                 845             


Val Thr Pro Glu Arg Ser Phe Ser Ala Ser Gly Ala Gln Ile Val Ser 
    850                 855                 860                 


Arg Trp Pro Pro Leu Pro Gly Thr Leu Leu Thr Glu Ala Ser Ala Leu 
865                 870                 875                 880 


Ser Met Met Asp Pro Ser Pro Ser Lys Thr Pro Ile Thr Leu Leu Gly 
                885                 890                 895     


Pro Arg Val Leu Ser Pro Thr Thr Ser Arg Leu Ser Thr Ala Leu Ala 
            900                 905                 910         


Ala Thr Thr His Pro Gly Pro Gln Gln Pro Pro Val Gly Ala Ser Arg 
        915                 920                 925             


Gly Glu Glu Ser Thr Met 
    930                 


<210>  1383
<211>  529
<212>  PRT
<213>  Homo Sapiens

<400>  1383

Ala Gly Leu Leu Pro Gly Leu Gly Ser His Pro Gly Val Cys Pro Asn 
1               5                   10                  15      


Gln Leu Ser Pro Asn Leu Trp Val Asp Ala Gln Ser Thr Cys Glu Arg 
            20                  25                  30          


Glu Cys Ser Arg Asp Gln Asp Cys Ala Ala Ala Glu Lys Cys Cys Ile 
        35                  40                  45              


Asn Val Cys Gly Leu His Ser Cys Val Ala Ala Arg Phe Pro Gly Ser 
    50                  55                  60                  


Pro Ala Ala Pro Thr Thr Ala Ala Ser Cys Glu Gly Phe Val Cys Pro 
65                  70                  75                  80  


Gln Gln Gly Ser Asp Cys Asp Ile Trp Asp Gly Gln Pro Val Cys Arg 
                85                  90                  95      


Cys Arg Asp Arg Cys Glu Lys Glu Pro Ser Phe Thr Cys Ala Ser Asp 
            100                 105                 110         


Gly Leu Thr Tyr Tyr Asn Arg Cys Tyr Met Asp Ala Glu Ala Cys Leu 
        115                 120                 125             


Arg Gly Leu His Leu His Ile Val Pro Cys Lys His Val Leu Ser Trp 
    130                 135                 140                 


Pro Pro Ser Ser Pro Gly Pro Pro Glu Thr Thr Ala Arg Pro Thr Pro 
145                 150                 155                 160 


Gly Ala Ala Pro Val Pro Pro Ala Leu Tyr Ser Ser Pro Ser Pro Gln 
                165                 170                 175     


Ala Val Gln Val Gly Gly Thr Ala Ser Leu His Cys Asp Val Ser Gly 
            180                 185                 190         


Arg Pro Pro Pro Ala Val Thr Trp Glu Lys Gln Ser His Gln Arg Glu 
        195                 200                 205             


Asn Leu Ile Met Arg Pro Asp Gln Met Tyr Gly Asn Val Val Val Thr 
    210                 215                 220                 


Ser Ile Gly Gln Leu Val Leu Tyr Asn Ala Arg Pro Glu Asp Ala Gly 
225                 230                 235                 240 


Leu Tyr Thr Cys Thr Ala Arg Asn Ala Ala Gly Leu Leu Arg Ala Asp 
                245                 250                 255     


Phe Pro Leu Ser Val Val Gln Arg Glu Pro Ala Arg Asp Ala Ala Pro 
            260                 265                 270         


Ser Ile Pro Ala Pro Ala Glu Cys Leu Pro Asp Val Gln Ala Cys Thr 
        275                 280                 285             


Gly Pro Thr Ser Pro His Leu Val Leu Trp His Tyr Asp Pro Gln Arg 
    290                 295                 300                 


Gly Gly Cys Met Thr Phe Pro Ala Arg Gly Cys Asp Gly Ala Ala Arg 
305                 310                 315                 320 


Gly Phe Glu Thr Tyr Glu Ala Cys Gln Gln Ala Cys Ala Arg Gly Pro 
                325                 330                 335     


Gly Asp Ala Cys Val Leu Pro Ala Val Gln Gly Pro Cys Arg Gly Trp 
            340                 345                 350         


Glu Pro Arg Trp Ala Tyr Ser Pro Leu Leu Gln Gln Cys His Pro Phe 
        355                 360                 365             


Val Tyr Gly Gly Cys Glu Gly Asn Gly Asn Asn Phe His Ser Arg Glu 
    370                 375                 380                 


Ser Cys Glu Asp Ala Cys Pro Val Pro Arg Thr Pro Pro Cys Arg Ala 
385                 390                 395                 400 


Cys Arg Leu Arg Ser Lys Leu Ala Leu Ser Leu Cys Arg Ser Asp Phe 
                405                 410                 415     


Ala Ile Val Gly Arg Leu Thr Glu Val Leu Glu Glu Pro Glu Ala Ala 
            420                 425                 430         


Gly Gly Ile Ala Arg Val Ala Leu Glu Asp Val Leu Lys Asp Asp Lys 
        435                 440                 445             


Met Gly Leu Lys Phe Leu Gly Thr Lys Tyr Leu Glu Val Thr Leu Ser 
    450                 455                 460                 


Gly Met Asp Trp Ala Cys Pro Cys Pro Asn Met Thr Ala Gly Asp Gly 
465                 470                 475                 480 


Pro Leu Val Ile Met Gly Glu Val Arg Asp Gly Val Ala Val Leu Asp 
                485                 490                 495     


Ala Gly Ser Tyr Val Arg Ala Ala Ser Glu Lys Arg Val Lys Lys Ile 
            500                 505                 510         


Leu Glu Leu Leu Glu Lys Gln Ala Cys Glu Leu Leu Asn Arg Phe Gln 
        515                 520                 525             


Asp 
    


<210>  1384
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  1384

Leu Pro Pro Ile Arg Tyr Ser His Ala Gly Ile Cys Pro Asn Asp Met 
1               5                   10                  15      


Asn Pro Asn Leu Trp Val Asp Ala Gln Ser Thr Cys Arg Arg Glu Cys 
            20                  25                  30          


Glu Thr Asp Gln Glu Cys Glu Thr Tyr Glu Lys Cys Cys Pro Asn Val 
        35                  40                  45              


Cys Gly Thr Lys Ser Cys Val Ala Ala Arg Tyr Met Asp Val Lys Gly 
    50                  55                  60                  


Lys Lys Gly Pro Val Gly Met Pro Lys Glu Ala Thr Cys Asp His Phe 
65                  70                  75                  80  


Met Cys Leu Gln Gln Gly Ser Glu Cys Asp Ile Trp Asp Gly Gln Pro 
                85                  90                  95      


Val Cys Lys Cys Lys Asp Arg Cys Glu Lys Glu Pro Ser Phe Thr Cys 
            100                 105                 110         


Ala Ser Asp Gly Leu Thr Tyr Tyr Asn Arg Cys Tyr Met Asp Ala Glu 
        115                 120                 125             


Ala Cys Ser Lys Gly Ile Thr Leu Ala Val Val Thr Cys Arg Tyr His 
    130                 135                 140                 


Phe Thr Trp Pro Asn Thr Ser Pro Pro Pro Pro Glu Thr Thr Met His 
145                 150                 155                 160 


Pro Thr Thr Ala Ser Pro Glu Thr Pro Glu Leu Asp Met Ala Ala Pro 
                165                 170                 175     


Ala Leu Leu Asn Asn Pro Val His Gln Ser Val Thr Met Gly Glu Thr 
            180                 185                 190         


Val Ser Phe Leu Cys Asp Val Val Gly Arg Pro Arg Pro Glu Ile Thr 
        195                 200                 205             


Trp Glu Lys Gln Leu Glu Asp Arg Glu Asn Val Val Met Arg Pro Asn 
    210                 215                 220                 


His Val Arg Gly Asn Val Val Val Thr Asn Ile Ala Gln Leu Val Ile 
225                 230                 235                 240 


Tyr Asn Ala Gln Leu Gln Asp Ala Gly Ile Tyr Thr Cys Thr Ala Arg 
                245                 250                 255     


Asn Val Ala Gly Val Leu Arg Ala Asp Phe Pro Leu Ser Val Val Arg 
            260                 265                 270         


Gly His Gln Ala Ala Ala Thr Ser Glu Ser Ser Pro Asn Gly Thr Ala 
        275                 280                 285             


Phe Pro Ala Ala Glu Cys Leu Lys Pro Pro Asp Ser Glu Asp Cys Gly 
    290                 295                 300                 


Glu Glu Gln Thr Arg Trp His Phe Asp Ala Gln Ala Asn Asn Cys Leu 
305                 310                 315                 320 


Thr Phe Thr Phe Gly His Cys His Arg Asn Leu Asn His Phe Glu Thr 
                325                 330                 335     


Tyr Glu Ala Cys Met Leu Ala Cys Met Ser Gly Pro Leu Ala Ala Cys 
            340                 345                 350         


Ser Leu Pro Ala Leu Gln Gly Pro Cys Lys Ala Tyr Ala Pro Arg Trp 
        355                 360                 365             


Ala Tyr Asn Ser Gln Thr Gly Gln Cys Gln Ser Phe Val Tyr Gly Gly 
    370                 375                 380                 


Cys Glu Gly Asn Gly Asn Asn Phe Glu Ser Arg Glu Ala Cys Glu Glu 
385                 390                 395                 400 


Ser Cys Pro Phe Pro Arg Gly Asn Gln Arg Cys Arg Ala Cys Lys Pro 
                405                 410                 415     


Arg Gln Lys Leu Val Thr Ser Phe Cys Arg Ser Asp Phe Val Ile Leu 
            420                 425                 430         


Gly Arg Val Ser Glu Leu Thr Glu Glu Pro Asp Ser Gly Arg Ala Leu 
        435                 440                 445             


Val Thr Val Asp Glu Val Leu Lys Asp Glu Lys Met Gly Leu Lys Phe 
    450                 455                 460                 


Leu Gly Gln Glu Pro Leu Glu Val Thr Leu Leu His Val Asp Trp Ala 
465                 470                 475                 480 


Cys Pro Cys Pro Asn Val Thr Val Ser Glu Met Pro Leu Ile Ile Met 
                485                 490                 495     


Gly Glu Val Asp Gly Gly Met Ala Met Leu Arg Pro Asp Ser Phe Val 
            500                 505                 510         


Gly Ala Ser Ser Ala Arg Arg Val Arg Lys Leu Arg Glu Val Met His 
        515                 520                 525             


Lys Lys Thr Cys Asp Val Leu Lys Glu Phe Leu Gly Leu His 
    530                 535                 540         


<210>  1385
<211>  351
<212>  PRT
<213>  Homo Sapiens

<400>  1385

Gly Pro Pro Gln Glu Glu Ser Leu Tyr Leu Trp Ile Asp Ala His Gln 
1               5                   10                  15      


Ala Arg Val Leu Ile Gly Phe Glu Glu Asp Ile Leu Ile Val Ser Glu 
            20                  25                  30          


Gly Lys Met Ala Pro Phe Thr His Asp Phe Arg Lys Ala Gln Gln Arg 
        35                  40                  45              


Met Pro Ala Ile Pro Val Asn Ile His Ser Met Asn Phe Thr Trp Gln 
    50                  55                  60                  


Ala Ala Gly Gln Ala Glu Tyr Phe Tyr Glu Phe Leu Ser Leu Arg Ser 
65                  70                  75                  80  


Leu Asp Lys Gly Ile Met Ala Asp Pro Thr Val Asn Val Pro Leu Leu 
                85                  90                  95      


Gly Thr Val Pro His Lys Ala Ser Val Val Gln Val Gly Phe Pro Cys 
            100                 105                 110         


Leu Gly Lys Gln Asp Gly Val Ala Ala Phe Glu Val Asp Val Ile Val 
        115                 120                 125             


Met Asn Ser Glu Gly Asn Thr Ile Leu Lys Thr Pro Gln Asn Ala Ile 
    130                 135                 140                 


Phe Phe Lys Thr Cys Gln Gln Ala Glu Cys Pro Gly Gly Cys Arg Asn 
145                 150                 155                 160 


Gly Gly Phe Cys Asn Glu Arg Arg Ile Cys Glu Cys Pro Asp Gly Phe 
                165                 170                 175     


His Gly Pro His Cys Glu Lys Ala Leu Cys Thr Pro Arg Cys Met Asn 
            180                 185                 190         


Gly Gly Leu Cys Val Thr Pro Gly Phe Cys Ile Cys Pro Pro Gly Phe 
        195                 200                 205             


Tyr Gly Val Asn Cys Asp Lys Ala Asn Cys Ser Thr Thr Cys Phe Asn 
    210                 215                 220                 


Gly Gly Thr Cys Phe Tyr Pro Gly Lys Cys Ile Cys Pro Pro Gly Leu 
225                 230                 235                 240 


Glu Gly Glu Gln Cys Glu Ile Ser Lys Cys Pro Gln Pro Cys Arg Asn 
                245                 250                 255     


Gly Gly Lys Cys Ile Gly Lys Ser Lys Cys Lys Cys Ser Lys Gly Tyr 
            260                 265                 270         


Gln Gly Asp Leu Cys Ser Lys Pro Val Cys Glu Pro Gly Cys Gly Ala 
        275                 280                 285             


His Gly Thr Cys His Glu Pro Asn Lys Cys Gln Cys Gln Glu Gly Trp 
    290                 295                 300                 


His Gly Arg His Cys Asn Lys Arg Tyr Glu Ala Ser Leu Ile His Ala 
305                 310                 315                 320 


Leu Arg Pro Ala Gly Ala Gln Leu Arg Gln His Thr Pro Ser Leu Lys 
                325                 330                 335     


Lys Ala Glu Glu Arg Arg Asp Pro Pro Glu Ser Asn Tyr Ile Trp 
            340                 345                 350     


<210>  1386
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1386

Val Gly Ser Glu Val Ser Asp Lys Arg Thr Cys Val Ser Leu Thr Thr 
1               5                   10                  15      


Gln Arg Leu Pro Val Ser Arg Ile Lys Thr Tyr Thr Ile Thr Glu Gly 
            20                  25                  30          


Ser Leu Arg Ala Val Ile Phe Ile Thr Lys Arg Gly Leu Lys Val Cys 
        35                  40                  45              


Ala Asp Pro Gln Ala Thr Trp Val Arg Asp Val Val Arg Ser Met Asp 
    50                  55                  60                  


Arg Lys Ser Asn Thr Arg Asn Asn Met Ile Gln Thr Lys Pro Thr Gly 
65                  70                  75                  80  


Thr Gln Gln Ser Thr Asn Thr Ala Val Thr Leu Thr Gly 
                85                  90              


<210>  1387
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1387

Val Gly Ser Glu Val Ser His Arg Arg Thr Cys Val Ser Leu Thr Thr 
1               5                   10                  15      


Gln Arg Leu Pro Val Ser Arg Ile Lys Thr Tyr Thr Ile Thr Glu Gly 
            20                  25                  30          


Ser Leu Arg Ala Val Ile Phe Ile Thr Lys Arg Gly Leu Lys Val Cys 
        35                  40                  45              


Ala Asp Pro Gln Ala Thr Trp Val Arg Asp Val Val Arg Ser Met Asp 
    50                  55                  60                  


Arg Lys Ser Asn Thr Arg Asn Asn Met Ile Gln Thr Lys Pro Thr Gly 
65                  70                  75                  80  


Thr Gln Gln Ser Thr Asn Thr Ala Val Thr Leu Thr Gly 
                85                  90              


<210>  1388
<211>  307
<212>  PRT
<213>  Homo Sapiens

<400>  1388

His Leu Val Arg Leu Pro Arg Ala Phe Arg Leu Thr Lys Asp Ser Val 
1               5                   10                  15      


Lys Ile Val Gly Ser Thr Ser Phe Pro Val Lys Ala Tyr Val Met Leu 
            20                  25                  30          


His Gln Lys Ser Pro His Val Leu Cys Val Thr Gln Gln Leu Arg Asn 
        35                  40                  45              


Ala Glu Leu Ile Asp Pro Ser Phe Gln Trp Tyr Gly Pro Lys Gly Lys 
    50                  55                  60                  


Val Val Ser Val Glu Asn Arg Thr Ala Gln Ile Thr Ser Thr Gly Ser 
65                  70                  75                  80  


Leu Val Phe Gln Asn Phe Glu Glu Ser Met Ser Gly Ile Tyr Thr Cys 
                85                  90                  95      


Phe Leu Glu Tyr Lys Pro Thr Val Glu Glu Ile Val Lys Arg Leu Gln 
            100                 105                 110         


Leu Lys Tyr Ala Ile Tyr Ala Tyr Arg Glu Pro His Tyr Tyr Tyr Gln 
        115                 120                 125             


Phe Thr Ala Arg Tyr His Ala Ala Pro Cys Asn Ser Ile Tyr Asn Ile 
    130                 135                 140                 


Ser Phe Glu Lys Lys Leu Leu Gln Ile Leu Ser Lys Leu Leu Leu Asp 
145                 150                 155                 160 


Leu Ser Cys Glu Ile Ser Leu Leu Lys Ser Glu Cys His Arg Val Lys 
                165                 170                 175     


Met Gln Arg Ala Gly Leu Gln Asn Glu Leu Phe Phe Ala Phe Ser Val 
            180                 185                 190         


Ser Ser Leu Asp Thr Glu Lys Gly Pro Lys Arg Cys Thr Asp His Asn 
        195                 200                 205             


Cys Glu Pro Tyr Lys Arg Leu Phe Lys Ala Lys Asn Leu Ile Glu Arg 
    210                 215                 220                 


Phe Phe Asn Gln Gln Val Glu Ile Leu Gly Arg Arg Ala Glu Gln Leu 
225                 230                 235                 240 


Pro Gln Ile Tyr Tyr Ile Glu Gly Thr Leu Gln Met Val Trp Ile Asn 
                245                 250                 255     


Arg Cys Phe Pro Gly Tyr Gly Met Asn Val Gln Gln His Pro Lys Cys 
            260                 265                 270         


Pro Glu Cys Cys Val Ile Cys Ser Pro Gly Ser Tyr Asn Pro Arg Asp 
        275                 280                 285             


Gly Ile His Cys Leu Gln Cys Asn Ser Ser Leu Val Tyr Gly Ala Lys 
    290                 295                 300                 


Thr Cys Leu 
305         


<210>  1389
<211>  299
<212>  PRT
<213>  Homo Sapiens

<400>  1389

Asp Lys Ile Tyr Val Glu Leu His Gln Asn Ser Pro Val Leu Ile Cys 
1               5                   10                  15      


Met Asp Phe Lys Leu Ser Lys Lys Glu Ile Val Asp Pro Thr Tyr Leu 
            20                  25                  30          


Trp Ile Gly Pro Asn Glu Lys Thr Leu Thr Gly Asn Asn Arg Ile Asn 
        35                  40                  45              


Ile Thr Glu Thr Gly Gln Leu Met Val Lys Asp Phe Leu Glu Pro Leu 
    50                  55                  60                  


Ser Gly Leu Tyr Thr Cys Thr Leu Ser Tyr Lys Thr Val Lys Ala Glu 
65                  70                  75                  80  


Thr Gln Glu Glu Lys Thr Val Lys Lys Arg Tyr Asp Phe Met Val Phe 
                85                  90                  95      


Ala Tyr Arg Glu Pro Asp Tyr Ser Tyr Gln Met Ala Val Arg Phe Thr 
            100                 105                 110         


Thr Arg Ser Cys Ile Gly Arg Tyr Asn Asp Val Phe Phe Arg Val Leu 
        115                 120                 125             


Lys Lys Ile Leu Asp Ser Leu Ile Ser Asp Leu Ser Cys His Val Ile 
    130                 135                 140                 


Glu Pro Ser Tyr Lys Cys His Ser Val Glu Ile Pro Glu His Gly Leu 
145                 150                 155                 160 


Ile His Glu Leu Phe Ile Ala Phe Gln Val Asn Pro Phe Ala Pro Gly 
                165                 170                 175     


Trp Lys Gly Ala Cys Asn Gly Ser Val Asp Cys Glu Asp Thr Thr Asn 
            180                 185                 190         


His Asn Ile Leu Gln Ala Arg Asp Arg Ile Glu Asp Phe Phe Arg Ser 
        195                 200                 205             


Gln Ala Tyr Ile Phe Tyr His Asn Phe Asn Lys Thr Leu Pro Ala Met 
    210                 215                 220                 


His Phe Val Asp His Ser Leu Gln Val Val Arg Leu Asp Ser Cys Arg 
225                 230                 235                 240 


Pro Gly Phe Gly Lys Asn Glu Arg Leu His Ser Asn Cys Ala Ser Cys 
                245                 250                 255     


Cys Val Val Cys Ser Pro Ala Thr Phe Ser Pro Asp Val Asn Val Thr 
            260                 265                 270         


Cys Gln Thr Cys Val Ser Val Leu Thr Tyr Gly Ala Lys Ser Cys Pro 
        275                 280                 285             


Gln Thr Ser Asn Lys Asn Gln Gln Tyr Glu Asp 
    290                 295                 


<210>  1390
<211>  310
<212>  PRT
<213>  Homo Sapiens

<400>  1390

Met Asn Gly Leu Ser Leu Ser Glu Leu Cys Cys Leu Phe Cys Cys Pro 
1               5                   10                  15      


Pro Cys Pro Gly Arg Ile Ala Ala Lys Leu Ala Phe Leu Pro Pro Glu 
            20                  25                  30          


Ala Thr Tyr Ser Leu Val Pro Glu Pro Glu Pro Gly Pro Gly Gly Ala 
        35                  40                  45              


Gly Ala Ala Pro Leu Gly Thr Leu Arg Ala Ser Ser Gly Ala Pro Gly 
    50                  55                  60                  


Arg Trp Lys Leu His Leu Thr Glu Arg Ala Asp Phe Gln Tyr Ser Gln 
65                  70                  75                  80  


Arg Glu Leu Asp Thr Ile Glu Val Phe Pro Thr Lys Ser Ala Arg Gly 
                85                  90                  95      


Asn Arg Val Ser Cys Met Tyr Val Arg Cys Val Pro Gly Ala Arg Tyr 
            100                 105                 110         


Thr Val Leu Phe Ser His Gly Asn Ala Val Asp Leu Gly Gln Met Ser 
        115                 120                 125             


Ser Phe Tyr Ile Gly Leu Gly Ser Arg Leu His Cys Asn Ile Phe Ser 
    130                 135                 140                 


Tyr Asp Tyr Ser Gly Tyr Gly Ala Ser Ser Gly Arg Pro Ser Glu Arg 
145                 150                 155                 160 


Asn Leu Tyr Ala Asp Ile Asp Ala Ala Trp Gln Ala Leu Arg Thr Arg 
                165                 170                 175     


Tyr Gly Ile Ser Pro Asp Ser Ile Ile Leu Tyr Gly Gln Ser Ile Gly 
            180                 185                 190         


Thr Val Pro Thr Val Asp Leu Ala Ser Arg Tyr Glu Cys Ala Ala Val 
        195                 200                 205             


Val Leu His Ser Pro Leu Thr Ser Gly Met Arg Val Ala Phe Pro Asp 
    210                 215                 220                 


Thr Lys Lys Thr Tyr Cys Phe Asp Ala Phe Pro Asn Ile Glu Lys Val 
225                 230                 235                 240 


Ser Lys Ile Thr Ser Pro Val Leu Ile Ile His Gly Thr Glu Asp Glu 
                245                 250                 255     


Val Ile Asp Phe Ser His Gly Leu Ala Leu Tyr Glu Arg Cys Pro Lys 
            260                 265                 270         


Ala Val Glu Pro Leu Trp Val Glu Gly Ala Gly His Asn Asp Ile Glu 
        275                 280                 285             


Leu Tyr Ser Gln Tyr Leu Glu Arg Leu Arg Arg Phe Ile Ser Gln Glu 
    290                 295                 300                 


Leu Pro Ser Gln Arg Ala 
305                 310 


<210>  1391
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  1391

Met Asn Asn Leu Ser Phe Ser Glu Leu Cys Cys Leu Phe Cys Cys Pro 
1               5                   10                  15      


Pro Cys Pro Gly Lys Ile Ala Ser Lys Leu Ala Phe Leu Pro Pro Asp 
            20                  25                  30          


Pro Thr Tyr Thr Leu Met Cys Asp Glu Ser Gly Ser Arg Trp Thr Leu 
        35                  40                  45              


His Leu Ser Glu Arg Ala Asp Trp Gln Tyr Ser Ser Arg Glu Lys Asp 
    50                  55                  60                  


Ala Ile Glu Cys Phe Met Thr Arg Thr Ser Lys Gly Asn Arg Ile Ala 
65                  70                  75                  80  


Cys Met Phe Val Arg Cys Ser Pro Asn Ala Lys Tyr Thr Leu Leu Phe 
                85                  90                  95      


Ser His Gly Asn Ala Val Asp Leu Gly Gln Met Ser Ser Phe Tyr Ile 
            100                 105                 110         


Gly Leu Gly Ser Arg Ile Asn Cys Asn Ile Phe Ser Tyr Asp Tyr Ser 
        115                 120                 125             


Gly Tyr Gly Ala Ser Ser Gly Lys Pro Thr Glu Lys Asn Leu Tyr Ala 
    130                 135                 140                 


Asp Ile Glu Ala Ala Trp Leu Ala Leu Arg Thr Arg Tyr Gly Ile Arg 
145                 150                 155                 160 


Pro Glu Asn Val Ile Ile Tyr Gly Gln Ser Ile Gly Thr Val Pro Ser 
                165                 170                 175     


Val Asp Leu Ala Ala Arg Tyr Glu Ser Ala Ala Val Ile Leu His Ser 
            180                 185                 190         


Pro Leu Thr Ser Gly Met Arg Val Ala Phe Pro Asp Thr Lys Lys Thr 
        195                 200                 205             


Tyr Cys Phe Asp Ala Phe Pro Asn Ile Asp Lys Ile Ser Lys Ile Thr 
    210                 215                 220                 


Ser Pro Val Leu Ile Ile His Gly Thr Glu Asp Glu Val Ile Asp Phe 
225                 230                 235                 240 


Ser His Gly Leu Ala Leu Phe Glu Arg Cys Gln Arg Pro Val Glu Pro 
                245                 250                 255     


Leu Trp Val Glu Gly Ala Gly His Asn Asp Val Glu Leu Tyr Gly Gln 
            260                 265                 270         


Tyr Leu Glu Arg Leu Lys Gln Phe Val Ser Gln Glu Leu Val Asn Leu 
        275                 280                 285             


<210>  1392
<211>  390
<212>  PRT
<213>  Homo Sapiens

<400>  1392

Arg Pro Glu Asp Leu Lys Arg Leu Phe Glu Phe Arg Lys Met Ile Gly 
1               5                   10                  15      


Asn Arg Glu Arg Cys Gln Asn Leu Val Ser Ser Asp Tyr Pro Val His 
            20                  25                  30          


Ile Asp Lys Ile Glu Glu Gln Ser Asp Cys Lys Ile Leu Asp Gly His 
        35                  40                  45              


Phe Val Ser Pro Met Ala His Tyr Val Pro Asp Ile Met Pro Ile Glu 
    50                  55                  60                  


Ser Val Ile Ala Arg Phe Gln Phe Ile Val Pro Lys Glu Trp Asn Ser 
65                  70                  75                  80  


Lys Tyr Arg Pro Val Cys Ile His Leu Ala Gly Thr Gly Asp His His 
                85                  90                  95      


Tyr Trp Arg Arg Arg Thr Leu Met Ala Arg Pro Met Ile Lys Glu Ala 
            100                 105                 110         


Arg Met Ala Ser Leu Leu Leu Glu Asn Pro Tyr Tyr Gly Cys Arg Lys 
        115                 120                 125             


Pro Lys Asp Gln Val Arg Ser Ser Leu Lys Asn Val Ser Asp Leu Phe 
    130                 135                 140                 


Val Met Gly Gly Ala Leu Val Leu Glu Ser Ala Ala Leu Leu His Trp 
145                 150                 155                 160 


Leu Glu Arg Glu Gly Tyr Gly Pro Leu Gly Met Thr Gly Ile Ser Met 
                165                 170                 175     


Gly Gly His Met Ala Ser Leu Ala Val Ser Asn Trp Pro Lys Pro Met 
            180                 185                 190         


Pro Leu Ile Pro Cys Leu Ser Trp Ser Thr Ala Ser Gly Val Phe Thr 
        195                 200                 205             


Thr Thr Asp Ser Phe Lys Met Gly Gln Glu Phe Val Lys His Phe Thr 
    210                 215                 220                 


Ser Ser Ala Asp Lys Leu Thr Asn Leu Asn Leu Val Ser Arg Thr Leu 
225                 230                 235                 240 


Asn Leu Asp Ile Ser Asn Gln Val Val Ser Gln Lys Pro Ala Asp Cys 
                245                 250                 255     


His Asn Ser Ser Lys Thr Ser Val Ser Ala Thr Ser Glu Gly Leu Leu 
            260                 265                 270         


Leu Gln Asp Thr Ser Lys Met Lys Arg Phe Asn Gln Thr Leu Ser Thr 
        275                 280                 285             


Asn Lys Ser Gly Tyr Thr Ser Arg Asn Pro Gln Ser Tyr His Leu Leu 
    290                 295                 300                 


Ser Lys Glu Gln Ser Arg Asn Ser Leu Arg Lys Glu Ser Leu Ile Phe 
305                 310                 315                 320 


Met Lys Gly Val Met Asp Glu Cys Thr His Val Ala Asn Phe Ser Val 
                325                 330                 335     


Pro Val Asp Pro Ser Leu Ile Ile Val Val Gln Ala Lys Glu Asp Ala 
            340                 345                 350         


Tyr Ile Pro Arg Thr Gly Val Arg Ser Leu Gln Glu Ile Trp Pro Gly 
        355                 360                 365             


Cys Glu Ile Arg Tyr Leu Glu Gly Gly His Ile Ser Ala Tyr Leu Phe 
    370                 375                 380                 


Lys Gln Gly Leu Phe Arg 
385                 390 


<210>  1393
<211>  189
<212>  PRT
<213>  Homo Sapiens

<400>  1393

Ala Ser Trp Thr Ser Arg Gln Val Gly Glu Arg Thr Leu Thr Gly Ile 
1               5                   10                  15      


Val Ile Asp Ser Gly Asp Gly Val Thr His Val Ile Pro Val Ala Glu 
            20                  25                  30          


Gly Tyr Val Ile Gly Ser Cys Ile Lys His Ile Pro Ile Ala Gly Arg 
        35                  40                  45              


Asp Ile Thr Tyr Phe Ile Gln Gln Leu Leu Arg Glu Arg Glu Val Gly 
    50                  55                  60                  


Ile Pro Pro Glu Gln Ser Leu Glu Thr Ala Lys Ala Ile Lys Glu Lys 
65                  70                  75                  80  


Tyr Cys Tyr Ile Cys Pro Asp Ile Val Lys Glu Phe Ala Lys Tyr Asp 
                85                  90                  95      


Val Asp Pro Gln Lys Trp Ile Lys Gln Tyr Thr Gly Ile Asn Ala Ile 
            100                 105                 110         


Asn Gln Lys Lys Phe Val Ile Asp Val Gly Tyr Glu Arg Phe Leu Gly 
        115                 120                 125             


Pro Glu Ile Phe Phe His Pro Glu Phe Ala Asn Pro Asp Ser Met Glu 
    130                 135                 140                 


Ser Ile Ser Asp Val Val Asp Glu Val Ile Gln Asn Cys Pro Ile Asp 
145                 150                 155                 160 


Val Arg Arg Pro Leu Tyr Lys Met Glu Gln Ile Pro Leu Ser Tyr Pro 
                165                 170                 175     


Gln Gly His Gly Phe His Pro Leu Ser Pro Pro Phe His 
            180                 185                 


<210>  1394
<211>  265
<212>  PRT
<213>  Homo Sapiens

<400>  1394

Lys Ser Pro Glu Lys Glu Asp Phe Leu Arg Ala Gln Lys Tyr Ile Asp 
1               5                   10                  15      


Leu Tyr Leu Val Leu Asp Asn Ala Phe Tyr Lys Asn Tyr Asn Glu Asn 
            20                  25                  30          


Leu Thr Leu Ile Arg Ser Phe Val Phe Asp Val Met Asn Leu Leu Asn 
        35                  40                  45              


Val Ile Tyr Asn Thr Ile Asp Val Gln Val Ala Leu Val Gly Met Glu 
    50                  55                  60                  


Ile Trp Ser Asp Gly Asp Lys Ile Lys Val Val Pro Ser Ala Ser Thr 
65                  70                  75                  80  


Thr Phe Asp Asn Phe Leu Arg Trp His Ser Ser Asn Leu Gly Lys Lys 
                85                  90                  95      


Ile His Asp His Ala Gln Leu Leu Ser Gly Ile Ser Phe Asn Asn Arg 
            100                 105                 110         


Arg Val Gly Leu Ala Ala Ser Asn Ser Leu Cys Ser Pro Ser Ser Val 
        115                 120                 125             


Ala Val Ile Glu Ala Lys Lys Lys Asn Asn Val Ala Leu Val Gly Val 
    130                 135                 140                 


Met Ser His Glu Leu Gly His Val Leu Gly Met Pro Asp Val Pro Phe 
145                 150                 155                 160 


Asn Thr Lys Cys Pro Ser Gly Ser Cys Val Met Asn Gln Tyr Leu Ser 
                165                 170                 175     


Ser Lys Phe Pro Lys Asp Phe Ser Thr Ser Cys Arg Ala His Phe Glu 
            180                 185                 190         


Arg Tyr Leu Leu Ser Gln Lys Pro Lys Cys Leu Leu Gln Ala Pro Ile 
        195                 200                 205             


Pro Thr Asn Ile Met Thr Thr Pro Val Cys Gly Asn His Leu Leu Glu 
    210                 215                 220                 


Val Gly Glu Asp Cys Asp Cys Gly Ser Pro Lys Glu Cys Thr Asn Leu 
225                 230                 235                 240 


Cys Cys Glu Ala Leu Thr Cys Lys Leu Lys Pro Gly Thr Asp Cys Gly 
                245                 250                 255     


Gly Asp Ala Pro Asn His Thr Thr Glu 
            260                 265 


<210>  1395
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  1395

Gln Gly Pro Gly Glu Trp Thr Pro Trp Val Ser Trp Thr Arg Cys Ser 
1               5                   10                  15      


Ser Ser Cys Gly Arg Gly Val Ser Val Arg Ser Arg Arg Cys Leu Arg 
            20                  25                  30          


Leu Pro Gly Glu Glu Pro Cys Trp Gly Asp Ser His Glu Tyr Arg Leu 
        35                  40                  45              


Cys Gln Leu Pro Asp Cys Pro Pro Gly Ala Val Pro Phe Arg Asp Leu 
    50                  55                  60                  


Gln Cys Ala Leu Tyr Asn Gly Arg Pro Val Leu Gly Thr Gln Lys Thr 
65                  70                  75                  80  


Tyr Gln Trp Val Pro Phe His Gly Ala Pro Asn Gln Cys Asp Leu Asn 
                85                  90                  95      


Cys Leu Ala Glu Gly His Ala Phe Tyr His Ser Phe Gly Arg Val Leu 
            100                 105                 110         


Asp Gly Thr Ala Cys Ser Pro Gly Ala Gln Gly Val Cys Val Ala Gly 
        115                 120                 125             


Arg Cys Leu Ser Ala Gly Cys Asp Gly Leu Leu Gly Ser Gly Ala Leu 
    130                 135                 140                 


Glu Asp Arg Cys Gly Arg Cys Gly Gly Ala Asn Asp Ser Cys Leu Phe 
145                 150                 155                 160 


Val Gln Arg Val Phe Arg Asp Ala Gly Ala Phe Ala Gly Tyr Trp Asn 
                165                 170                 175     


Val Thr Leu Ile Pro Glu Gly Ala Arg His Ile Arg Val Glu His Arg 
            180                 185                 190         


Ser Arg Asn His Leu Ala Leu Met Gly Gly Asp Gly Arg Tyr Val Leu 
        195                 200                 205             


Asn Gly His Trp Val Val Ser Pro Pro Gly Thr Tyr Glu Ala Ala Gly 
    210                 215                 220                 


Thr His Val Val Tyr Thr Arg Asp Thr Gly Pro Gln Glu Thr Leu Gln 
225                 230                 235                 240 


Ala Ala Gly Pro Thr Ser His Asp Leu Leu Leu Gln Val Leu Leu Gln 
                245                 250                 255     


Glu Pro Asn Pro Gly Ile Glu Phe Glu Phe Trp Leu Pro Arg Glu Arg 
            260                 265                 270         


Tyr Ser Pro Phe Gln Ala Arg Val Gln Ala Leu Gly Trp Pro Leu Arg 
        275                 280                 285             


Gln Pro Gln Pro Arg Gly Val Glu Pro Gln Pro Pro Ala Ala Pro Ala 
    290                 295                 300                 


Val Thr Pro Ala Gln Thr Pro Thr Leu Ala Pro Asp Pro Cys Pro Pro 
305                 310                 315                 320 


Cys Pro Asp Thr Arg Gly Arg Ala His Arg Leu Leu His Tyr Cys Gly 
                325                 330                 335     


Ser Asp Phe Val Phe Gln Ala Arg Val Leu Gly His His His Gln Ala 
            340                 345                 350         


Gln Glu Thr Arg Tyr Glu Val Arg Ile Gln Leu Val Tyr Lys Asn Arg 
        355                 360                 365             


Ser Pro Leu Arg Ala Arg Glu Tyr Val Trp Ala Pro Gly His Cys Pro 
    370                 375                 380                 


Cys Pro Met Leu Ala Pro His Arg Asp Tyr Leu Met Ala Val Gln Arg 
385                 390                 395                 400 


Leu Val Ser Pro Asp Gly Thr Gln Asp Gln Leu Leu Leu Pro His Ala 
                405                 410                 415     


Gly Tyr Ala Arg Pro Trp Ser Pro Ala Glu Asp Ser Arg Ile Arg Leu 
            420                 425                 430         


Thr Ala Arg Arg Cys Pro Gly 
        435                 


<210>  1396
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  1396

Met Trp Ile Gln Gln Leu Leu Gly Leu Ser Ser Met Ser Ile Arg Trp 
1               5                   10                  15      


Pro Gly Arg Pro Leu Gly Ser His Ala Trp Ile Leu Ile Ala Met Phe 
            20                  25                  30          


Gln Leu Ala Val Asp Leu Pro Ala Cys Glu Ala Leu Gly Pro Gly Pro 
        35                  40                  45              


Glu Phe Trp Leu Leu Pro Arg Ser Pro Pro Arg Pro Pro Arg Leu Trp 
    50                  55                  60                  


Ser Phe Arg Ser Gly Gln Pro Ala Arg Val Pro Ala Pro Val Trp Ser 
65                  70                  75                  80  


Pro Arg Pro Pro Arg Val Glu Arg Ile His Gly Gln Met Gln Met Pro 
                85                  90                  95      


Arg Ala Arg Arg Ala His Arg Pro Arg Asp Gln Ala Ala Ala Leu Val 
            100                 105                 110         


Pro Lys Ala Gly Leu Ala Lys Pro Pro Ala Ala Ala Lys Ser Ser Pro 
        115                 120                 125             


Ser Leu Ala Ser Ser Ser Ser Ser Ser Ser Ser Ala Val Ala Gly Gly 
    130                 135                 140                 


Ala Pro Glu Gln Gln Ala Leu Leu Arg Arg Gly Lys Arg His Leu Gln 
145                 150                 155                 160 


Gly Asp Gly Leu Ser Ser Phe Asp Ser Arg Gly Ser Arg Pro Thr Thr 
                165                 170                 175     


Glu Thr Glu Phe Ile Ala Trp Gly Pro Thr Gly Asp Glu Glu Ala Leu 
            180                 185                 190         


Glu Ser Asn Thr Phe Pro Gly Val Tyr Gly Pro Thr Thr Val Ser Ile 
        195                 200                 205             


Leu Gln Thr Arg Lys Thr Thr Val Ala Ala Thr Thr Thr Thr Thr Thr 
    210                 215                 220                 


Thr Ala Thr Pro Met Thr Leu Gln Thr Lys Gly Phe Thr Glu Ser Leu 
225                 230                 235                 240 


Asp Pro Arg Arg Arg Ile Pro Gly Gly Val Ser Thr Thr Glu Pro Ser 
                245                 250                 255     


Thr Ser Pro Ser Asn Asn Gly Glu Val Thr Gln Pro Pro Arg Ile Leu 
            260                 265                 270         


Gly Glu Ala Ser Gly Leu Ala Val His Gln 
        275                 280         


<210>  1397
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  1397

Gly Ala Glu Pro Arg Glu Pro Ala Asp Gly Gln Ala Leu Leu Arg Leu 
1               5                   10                  15      


Val Val Glu Leu Val Gln Glu Leu Arg Lys His His Ser Ala Glu His 
            20                  25                  30          


Lys Gly Leu Gln Leu Leu Gly Arg Asp Cys Ala Leu Gly Arg Ala Glu 
        35                  40                  45              


Ala Ala Gly Leu Gly Pro Ser Pro Glu Gln Arg Val Glu Ile Val Pro 
    50                  55                  60                  


Arg Asp Leu Arg Met Lys Asp Lys Phe Leu Lys His Leu Thr Gly Pro 
65                  70                  75                  80  


Leu Tyr Phe Ser Pro Lys Cys Ser Lys His Phe His Arg Leu Tyr His 
                85                  90                  95      


Asn Thr Arg Asp Cys Thr Ile Pro Ala Tyr Tyr Lys Arg Cys Ala Arg 
            100                 105                 110         


Leu Leu Thr Arg Leu Ala Val Ser Pro Val Cys Met Glu Asp Lys Gln 
        115                 120                 125             


<210>  1398
<211>  535
<212>  PRT
<213>  Homo Sapiens

<400>  1398

Arg Ala Glu Glu Pro Ala Val Gly Thr Ser Gly Leu Ile Phe Arg Glu 
1               5                   10                  15      


Asp Leu Asp Trp Pro Pro Gly Ser Pro Gln Glu Pro Leu Cys Leu Val 
            20                  25                  30          


Ala Leu Gly Gly Asp Ser Asn Gly Ser Ser Ser Pro Leu Arg Val Val 
        35                  40                  45              


Gly Ala Leu Ser Ala Tyr Glu Gln Ala Phe Leu Gly Ala Val Gln Arg 
    50                  55                  60                  


Ala Arg Trp Gly Pro Arg Asp Leu Ala Thr Phe Gly Val Cys Asn Thr 
65                  70                  75                  80  


Gly Asp Arg Gln Ala Ala Leu Pro Ser Leu Arg Arg Leu Gly Ala Trp 
                85                  90                  95      


Leu Arg Asp Pro Gly Gly Gln Arg Leu Val Val Leu His Leu Glu Glu 
            100                 105                 110         


Val Thr Trp Glu Pro Thr Pro Ser Leu Arg Phe Gln Glu Pro Pro Pro 
        115                 120                 125             


Gly Gly Ala Gly Pro Pro Glu Leu Ala Leu Leu Val Leu Tyr Pro Gly 
    130                 135                 140                 


Pro Gly Pro Glu Val Thr Val Thr Arg Ala Gly Leu Pro Gly Ala Gln 
145                 150                 155                 160 


Ser Leu Cys Pro Ser Arg Asp Thr Arg Tyr Leu Val Leu Ala Val Asp 
                165                 170                 175     


Arg Pro Ala Gly Ala Trp Arg Gly Ser Gly Leu Ala Leu Thr Leu Gln 
            180                 185                 190         


Pro Arg Gly Glu Asp Ser Arg Leu Ser Thr Ala Arg Leu Gln Ala Leu 
        195                 200                 205             


Leu Phe Gly Asp Asp His Arg Cys Phe Thr Arg Met Thr Pro Ala Leu 
    210                 215                 220                 


Leu Leu Leu Pro Arg Ser Glu Pro Ala Pro Leu Pro Ala His Gly Gln 
225                 230                 235                 240 


Leu Asp Thr Val Pro Phe Pro Pro Pro Arg Pro Ser Ala Glu Leu Glu 
                245                 250                 255     


Glu Ser Pro Pro Ser Ala Asp Pro Phe Leu Glu Thr Leu Thr Arg Leu 
            260                 265                 270         


Val Arg Ala Leu Arg Val Pro Pro Ala Arg Ala Ser Ala Pro Arg Leu 
        275                 280                 285             


Ala Leu Asp Pro Asp Ala Leu Ala Gly Phe Pro Gln Gly Leu Val Asn 
    290                 295                 300                 


Leu Ser Asp Pro Ala Ala Leu Glu Arg Leu Leu Asp Gly Glu Glu Pro 
305                 310                 315                 320 


Leu Leu Leu Leu Leu Arg Pro Thr Ala Ala Thr Thr Gly Asp Pro Ala 
                325                 330                 335     


Pro Leu His Asp Pro Thr Ser Ala Pro Trp Ala Thr Ala Leu Ala Arg 
            340                 345                 350         


Arg Val Ala Ala Glu Leu Gln Ala Ala Ala Ala Glu Leu Arg Ser Leu 
        355                 360                 365             


Pro Gly Leu Pro Pro Ala Thr Ala Pro Leu Leu Ala Arg Leu Leu Ala 
    370                 375                 380                 


Leu Cys Pro Gly Gly Pro Gly Gly Leu Gly Asp Pro Leu Arg Ala Leu 
385                 390                 395                 400 


Leu Leu Leu Lys Ala Leu Gln Gly Leu Arg Val Glu Trp Arg Gly Arg 
                405                 410                 415     


Asp Pro Arg Gly Pro Gly Arg Ala Gln Arg Ser Ala Gly Ala Thr Ala 
            420                 425                 430         


Ala Asp Gly Pro Cys Ala Leu Arg Glu Leu Ser Val Asp Leu Arg Ala 
        435                 440                 445             


Glu Arg Ser Val Leu Ile Pro Glu Thr Tyr Gln Ala Asn Asn Cys Gln 
    450                 455                 460                 


Gly Val Cys Gly Trp Pro Gln Ser Asp Arg Asn Pro Arg Tyr Gly Asn 
465                 470                 475                 480 


His Val Val Leu Leu Leu Lys Met Gln Val Arg Gly Ala Ala Leu Ala 
                485                 490                 495     


Arg Pro Pro Cys Cys Val Pro Thr Ala Tyr Ala Gly Lys Leu Leu Ile 
            500                 505                 510         


Ser Leu Ser Glu Glu Arg Ile Ser Ala His His Val Pro Asn Met Val 
        515                 520                 525             


Ala Thr Glu Cys Gly Cys Arg 
    530                 535 


<210>  1399
<211>  338
<212>  PRT
<213>  Homo Sapiens

<400>  1399

Val Ser Lys Leu Trp Val Pro Asn Thr Asp Phe Asp Val Ala Ala Asn 
1               5                   10                  15      


Trp Ser Gln Asn Arg Thr Pro Cys Ala Gly Gly Ala Val Glu Phe Pro 
            20                  25                  30          


Ala Asp Lys Met Val Ser Val Leu Val Gln Glu Gly His Ala Val Ser 
        35                  40                  45              


Asp Met Leu Leu Pro Leu Asp Gly Glu Leu Val Leu Ala Ser Gly Ala 
    50                  55                  60                  


Gly Phe Gly Val Ser Asp Val Gly Ser His Leu Asp Cys Gly Ala Gly 
65                  70                  75                  80  


Glu Pro Ala Val Phe Arg Asp Ser Asp Arg Phe Ser Trp His Asp Pro 
                85                  90                  95      


His Leu Trp Arg Ser Gly Asp Glu Ala Pro Gly Leu Phe Phe Val Asp 
            100                 105                 110         


Ala Glu Arg Val Pro Cys Arg His Asp Asp Val Phe Phe Pro Pro Ser 
        115                 120                 125             


Ala Ser Phe Arg Val Gly Leu Gly Pro Gly Ala Ser Pro Val Arg Val 
    130                 135                 140                 


Arg Ser Ile Ser Ala Leu Gly Arg Thr Phe Thr Arg Asp Glu Asp Leu 
145                 150                 155                 160 


Ala Val Phe Leu Ala Ser Arg Ala Gly Arg Leu Arg Phe His Gly Pro 
                165                 170                 175     


Gly Ala Leu Ser Val Gly Pro Glu Asp Cys Ala Asp Pro Ser Gly Cys 
            180                 185                 190         


Val Cys Gly Asn Ala Glu Ala Gln Pro Trp Ile Cys Ala Ala Leu Leu 
        195                 200                 205             


Gln Pro Leu Gly Gly Arg Cys Pro Gln Ala Ala Cys His Ser Ala Leu 
    210                 215                 220                 


Arg Pro Gln Gly Gln Cys Cys Asp Leu Cys Gly Ala Val Val Leu Leu 
225                 230                 235                 240 


Thr His Gly Pro Ala Phe Asp Leu Glu Arg Tyr Arg Ala Arg Ile Leu 
                245                 250                 255     


Asp Thr Phe Leu Gly Leu Pro Gln Tyr His Gly Leu Gln Val Ala Val 
            260                 265                 270         


Ser Lys Val Pro Arg Ser Ser Arg Leu Arg Glu Ala Asp Thr Glu Ile 
        275                 280                 285             


Gln Val Val Leu Val Glu Asn Gly Pro Glu Thr Gly Gly Ala Gly Arg 
    290                 295                 300                 


Leu Ala Arg Ala Leu Leu Ala Asp Val Ala Glu Asn Gly Glu Ala Leu 
305                 310                 315                 320 


Gly Val Leu Glu Ala Thr Met Arg Glu Ser Gly Ala His Val Trp Gly 
                325                 330                 335     


Ser Ser 
        


<210>  1400
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  1400

Gln Tyr Ser Pro Asn Thr Gln Gln Gly Arg Thr Ser Ile Val His Leu 
1               5                   10                  15      


Phe Glu Trp Arg Trp Val Asp Ile Ala Leu Glu Cys Glu Arg Tyr Leu 
            20                  25                  30          


Ala Pro Lys Gly Phe Gly Gly Val Gln Val Ser Pro Pro Asn Glu Asn 
        35                  40                  45              


Val Ala Ile Tyr Asn Pro Phe Arg Pro Trp Trp Glu Arg Tyr Gln Pro 
    50                  55                  60                  


Val Ser Tyr Lys Leu Cys Thr Arg Ser Gly Asn Glu Asp Glu Phe Arg 
65                  70                  75                  80  


Asn Met Val Thr Arg Cys Asn Asn Val Gly Val Arg Ile Tyr Val Asp 
                85                  90                  95      


Ala Val Ile Asn His Met Cys Gly Asn Ala Val Ser Ala Gly Thr Ser 
            100                 105                 110         


Ser Thr Cys Gly Ser Tyr Phe Asn Pro Gly Ser Arg Asp Phe Pro Ala 
        115                 120                 125             


Val Pro Tyr Ser Gly Trp Asp Phe Asn Asp Gly Lys Cys Lys Thr Gly 
    130                 135                 140                 


Ser Gly Asp Ile Glu Asn Tyr Asn Asp Ala Thr Gln Val Arg Asp Cys 
145                 150                 155                 160 


Arg Leu Thr Gly Leu Leu Asp Leu Ala Leu Glu Lys Asp Tyr Val Arg 
                165                 170                 175     


Ser Lys Ile Ala Glu Tyr Met Asn His Leu Ile Asp Ile Gly Val Ala 
            180                 185                 190         


Gly Phe Arg Leu Asp Ala Ser Lys His Met Trp Pro Gly Asp Ile Lys 
        195                 200                 205             


Ala Ile Leu Asp Lys Leu His Asn Leu Asn Ser Asn Trp Phe Pro Ala 
    210                 215                 220                 


Gly Ser Lys Pro Phe Ile Tyr Gln Glu Val Ile Asp Leu Gly Gly Glu 
225                 230                 235                 240 


Pro Ile Lys Ser Ser Asp Tyr Phe Gly Asn Gly Arg Val Thr Glu Phe 
                245                 250                 255     


Lys Tyr Gly Ala Lys Leu Gly Thr Val Ile Arg Lys Trp Asn Gly Glu 
            260                 265                 270         


Lys Met Ser Tyr Leu Lys Asn Trp Gly Glu Gly Trp Gly Phe Val Pro 
        275                 280                 285             


Ser Asp Arg Ala Leu Val Phe Val Asp Asn His Asp Asn Gln Arg Gly 
    290                 295                 300                 


His Gly Ala Gly Gly Ala Ser Ile Leu Thr Phe Trp Asp Ala Arg Leu 
305                 310                 315                 320 


Tyr Lys Met Ala Val Gly Phe Met Leu Ala His Pro Tyr Gly Phe Thr 
                325                 330                 335     


Arg Val Met Ser Ser Tyr Arg Trp Pro Arg Gln Phe Gln Asn Gly Asn 
            340                 345                 350         


Asp Val Asn Asp Trp Val Gly Pro Pro Asn Asn Asn Gly Val Ile Lys 
        355                 360                 365             


Glu Val Thr Ile Asn Pro Asp Thr Thr Cys Gly Asn Asp Trp Val Cys 
    370                 375                 380                 


Glu His Arg Trp Arg Gln Ile Arg Asn Met Val Ile Phe Arg Asn Val 
385                 390                 395                 400 


Val Asp Gly Gln Pro Phe Thr Asn Trp Tyr Asp Asn Gly Ser Asn Gln 
                405                 410                 415     


Val Ala Phe Gly Arg Gly Asn Arg Gly Phe Ile Val Phe Asn Asn Asp 
            420                 425                 430         


Asp Trp Ser Phe Ser Leu Thr Leu Gln Thr Gly Leu Pro Ala Gly Thr 
        435                 440                 445             


Tyr Cys Asp Val Ile Ser Gly Asp Lys Ile Asn Gly Asn Cys Thr Gly 
    450                 455                 460                 


Ile Lys Ile Tyr Val Ser Asp Asp Gly Lys Ala His Phe Ser Ile Ser 
465                 470                 475                 480 


Asn Ser Ala Glu Asp Pro Phe Ile Ala Ile His Ala Glu Ser Lys Leu 
                485                 490                 495     


<210>  1401
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  1401

Gln Tyr Ser Pro Asn Thr Gln Gln Gly Arg Thr Ser Ile Val His Leu 
1               5                   10                  15      


Phe Glu Trp Arg Trp Val Asp Ile Ala Leu Glu Cys Glu Arg Tyr Leu 
            20                  25                  30          


Ala Pro Lys Gly Phe Gly Gly Val Gln Val Ser Pro Pro Asn Glu Asn 
        35                  40                  45              


Val Ala Ile His Asn Pro Phe Arg Pro Trp Trp Glu Arg Tyr Gln Pro 
    50                  55                  60                  


Val Ser Tyr Lys Leu Cys Thr Arg Ser Gly Asn Glu Asp Glu Phe Arg 
65                  70                  75                  80  


Asn Met Val Thr Arg Cys Asn Asn Val Gly Val Arg Ile Tyr Val Asp 
                85                  90                  95      


Ala Val Ile Asn His Met Ser Gly Asn Ala Val Ser Ala Gly Thr Ser 
            100                 105                 110         


Ser Thr Cys Gly Ser Tyr Phe Asn Pro Gly Ser Arg Asp Phe Pro Ala 
        115                 120                 125             


Val Pro Tyr Ser Gly Trp Asp Phe Asn Asp Gly Lys Cys Lys Thr Gly 
    130                 135                 140                 


Ser Gly Asp Ile Glu Asn Tyr Asn Asp Ala Thr Gln Val Arg Asp Cys 
145                 150                 155                 160 


Arg Leu Val Gly Leu Leu Asp Leu Ala Leu Glu Lys Asp Tyr Val Arg 
                165                 170                 175     


Ser Lys Ile Ala Glu Tyr Met Asn His Leu Ile Asp Ile Gly Val Ala 
            180                 185                 190         


Gly Phe Arg Leu Asp Ala Ser Lys His Met Trp Pro Gly Asp Ile Lys 
        195                 200                 205             


Ala Ile Leu Asp Lys Leu His Asn Leu Asn Ser Asn Trp Phe Pro Ala 
    210                 215                 220                 


Gly Ser Lys Pro Phe Ile Tyr Gln Glu Val Ile Asp Leu Gly Gly Glu 
225                 230                 235                 240 


Pro Ile Lys Ser Ser Asp Tyr Phe Gly Asn Gly Arg Val Thr Glu Phe 
                245                 250                 255     


Lys Tyr Gly Ala Lys Leu Gly Thr Val Ile Arg Lys Trp Asn Gly Glu 
            260                 265                 270         


Lys Met Ser Tyr Leu Lys Asn Trp Gly Glu Gly Trp Gly Phe Met Pro 
        275                 280                 285             


Ser Asp Arg Ala Leu Val Phe Val Asp Asn His Asp Asn Gln Arg Gly 
    290                 295                 300                 


His Gly Ala Gly Gly Ala Ser Ile Leu Thr Phe Trp Asp Ala Arg Leu 
305                 310                 315                 320 


Tyr Lys Met Ala Val Gly Phe Met Leu Ala His Pro Tyr Gly Phe Thr 
                325                 330                 335     


Arg Val Met Ser Ser Tyr Arg Trp Pro Arg Gln Phe Gln Asn Gly Asn 
            340                 345                 350         


Asp Val Asn Asp Trp Val Gly Pro Pro Asn Asn Asn Gly Val Ile Lys 
        355                 360                 365             


Glu Val Thr Ile Asn Pro Asp Thr Thr Cys Gly Asn Asp Trp Val Cys 
    370                 375                 380                 


Glu His Arg Trp Arg Gln Ile Arg Asn Met Val Asn Phe Arg Asn Val 
385                 390                 395                 400 


Val Asp Gly Gln Pro Phe Thr Asn Trp Tyr Asp Asn Gly Ser Asn Gln 
                405                 410                 415     


Val Ala Phe Gly Arg Gly Asn Arg Gly Phe Ile Val Phe Asn Asn Asp 
            420                 425                 430         


Asp Trp Thr Phe Ser Leu Thr Leu Gln Thr Gly Leu Pro Ala Gly Thr 
        435                 440                 445             


Tyr Cys Asp Val Ile Ser Gly Asp Lys Ile Asn Gly Asn Cys Thr Gly 
    450                 455                 460                 


Ile Lys Ile Tyr Val Ser Asp Asp Gly Lys Ala His Phe Ser Ile Ser 
465                 470                 475                 480 


Asn Ser Ala Glu Asp Pro Phe Ile Ala Ile His Ala Glu Ser Lys Leu 
                485                 490                 495     


<210>  1402
<211>  468
<212>  PRT
<213>  Homo Sapiens

<400>  1402

Gly Gln Phe Lys Ile Lys Lys Ile Asn Gln Arg Arg Tyr Pro Arg Ala 
1               5                   10                  15      


Thr Asp Gly Lys Glu Glu Ala Lys Lys Cys Ala Tyr Thr Phe Leu Val 
            20                  25                  30          


Pro Glu Gln Arg Ile Thr Gly Pro Ile Cys Val Asn Thr Lys Gly Gln 
        35                  40                  45              


Asp Ala Ser Thr Ile Lys Asp Met Ile Thr Arg Met Asp Leu Glu Asn 
    50                  55                  60                  


Leu Lys Asp Val Leu Ser Arg Gln Lys Arg Glu Ile Asp Val Leu Gln 
65                  70                  75                  80  


Leu Val Val Asp Val Asp Gly Asn Ile Val Asn Glu Val Lys Leu Leu 
                85                  90                  95      


Arg Lys Glu Ser Arg Asn Met Asn Ser Arg Val Thr Gln Leu Tyr Met 
            100                 105                 110         


Gln Leu Leu His Glu Ile Ile Arg Lys Arg Asp Asn Ser Leu Glu Leu 
        115                 120                 125             


Ser Gln Leu Glu Asn Lys Ile Leu Asn Val Thr Thr Glu Met Leu Lys 
    130                 135                 140                 


Met Ala Thr Arg Tyr Arg Glu Leu Glu Val Lys Tyr Ala Ser Leu Thr 
145                 150                 155                 160 


Asp Leu Val Asn Asn Gln Ser Val Met Ile Thr Leu Leu Glu Glu Gln 
                165                 170                 175     


Cys Leu Arg Ile Phe Ser Arg Gln Asp Thr His Val Ser Pro Pro Leu 
            180                 185                 190         


Val Gln Val Val Pro Gln His Ile Pro Asn Ser Gln Gln Tyr Thr Pro 
        195                 200                 205             


Gly Leu Leu Gly Gly Asn Glu Ile Gln Arg Asp Pro Gly Tyr Pro Arg 
    210                 215                 220                 


Asp Leu Met Pro Pro Pro Asp Leu Ala Thr Ser Pro Thr Lys Ser Pro 
225                 230                 235                 240 


Phe Lys Ile Pro Pro Val Thr Phe Ile Asn Glu Gly Pro Phe Lys Asp 
                245                 250                 255     


Cys Gln Gln Ala Lys Glu Ala Gly His Ser Val Ser Gly Ile Tyr Met 
            260                 265                 270         


Ile Lys Pro Glu Asn Ser Asn Gly Pro Met Gln Leu Trp Cys Glu Asn 
        275                 280                 285             


Ser Leu Asp Pro Gly Gly Trp Thr Val Ile Gln Lys Arg Thr Asp Gly 
    290                 295                 300                 


Ser Val Asn Phe Phe Arg Asn Trp Glu Asn Tyr Lys Lys Gly Phe Gly 
305                 310                 315                 320 


Asn Ile Asp Gly Glu Tyr Trp Leu Gly Leu Glu Asn Ile Tyr Met Leu 
                325                 330                 335     


Ser Asn Gln Asp Asn Tyr Lys Leu Leu Ile Glu Leu Glu Asp Trp Ser 
            340                 345                 350         


Asp Lys Lys Val Tyr Ala Glu Tyr Ser Ser Phe Arg Leu Glu Pro Glu 
        355                 360                 365             


Ser Glu Phe Tyr Arg Leu Arg Leu Gly Thr Tyr Gln Gly Asn Ala Gly 
    370                 375                 380                 


Asp Ser Met Met Trp His Asn Gly Lys Gln Phe Thr Thr Leu Asp Arg 
385                 390                 395                 400 


Asp Lys Asp Met Tyr Ala Gly Asn Cys Ala His Phe His Lys Gly Gly 
                405                 410                 415     


Trp Trp Tyr Asn Ala Cys Ala His Ser Asn Leu Asn Gly Val Trp Tyr 
            420                 425                 430         


Arg Gly Gly His Tyr Arg Ser Lys His Gln Asp Gly Ile Phe Trp Ala 
        435                 440                 445             


Glu Tyr Arg Gly Gly Ser Tyr Ser Leu Arg Ala Val Gln Met Met Ile 
    450                 455                 460                 


Lys Pro Ile Asp 
465             


<210>  1403
<211>  363
<212>  PRT
<213>  Homo Sapiens

<400>  1403

Asn Cys Val His His Ser Thr Asp Ser Ser Val Val Asn Ile Val Glu 
1               5                   10                  15      


Asp Gly Ser Asn Ala Lys Asp Glu Ser Lys Ser Asn Asp Thr Val Cys 
            20                  25                  30          


Lys Glu Asp Cys Glu Glu Ser Cys Asp Val Lys Thr Lys Ile Thr Arg 
        35                  40                  45              


Glu Glu Lys His Phe Met Cys Arg Asn Leu Gln Asn Ser Ile Val Ser 
    50                  55                  60                  


Tyr Thr Arg Ser Thr Lys Lys Leu Leu Arg Asn Met Met Asp Glu Gln 
65                  70                  75                  80  


Gln Ala Ser Leu Asp Tyr Leu Ser Asn Gln Val Asn Glu Leu Met Asn 
                85                  90                  95      


Arg Val Leu Leu Leu Thr Thr Glu Val Phe Arg Lys Gln Leu Asp Pro 
            100                 105                 110         


Phe Pro His Arg Pro Val Gln Ser His Gly Leu Asp Cys Thr Asp Ile 
        115                 120                 125             


Lys Asp Thr Ile Gly Ser Val Thr Lys Thr Pro Ser Gly Leu Tyr Ile 
    130                 135                 140                 


Ile His Pro Glu Gly Ser Ser Tyr Pro Phe Glu Val Met Cys Asp Met 
145                 150                 155                 160 


Asp Tyr Arg Gly Gly Gly Arg Thr Val Ile Gln Lys Arg Ile Asp Gly 
                165                 170                 175     


Ile Ile Asp Phe Gln Arg Leu Trp Cys Asp Tyr Leu Asp Gly Phe Gly 
            180                 185                 190         


Asp Leu Leu Gly Glu Phe Trp Leu Gly Leu Lys Lys Ile Phe Tyr Ile 
        195                 200                 205             


Val Asn Gln Lys Asn Thr Ser Phe Met Leu Tyr Val Ala Leu Glu Ser 
    210                 215                 220                 


Glu Asp Asp Thr Leu Ala Tyr Ala Ser Tyr Asp Asn Phe Trp Leu Glu 
225                 230                 235                 240 


Asp Glu Thr Arg Phe Phe Lys Met His Leu Gly Arg Tyr Ser Gly Asn 
                245                 250                 255     


Ala Gly Asp Ala Phe Arg Gly Leu Lys Lys Glu Asp Asn Gln Asn Ala 
            260                 265                 270         


Met Pro Phe Ser Thr Ser Asp Val Asp Asn Asp Gly Cys Arg Pro Ala 
        275                 280                 285             


Cys Leu Val Asn Gly Gln Ser Val Lys Ser Cys Ser His Leu His Asn 
    290                 295                 300                 


Lys Thr Gly Trp Trp Phe Asn Glu Cys Gly Leu Ala Asn Leu Asn Gly 
305                 310                 315                 320 


Ile His His Phe Ser Gly Lys Leu Leu Ala Thr Gly Ile Gln Trp Gly 
                325                 330                 335     


Thr Trp Thr Lys Asn Asn Ser Pro Val Lys Ile Lys Ser Val Ser Met 
            340                 345                 350         


Lys Ile Arg Arg Met Tyr Asn Pro Tyr Phe Lys 
        355                 360             


<210>  1404
<211>  450
<212>  PRT
<213>  Homo Sapiens

<400>  1404

Arg Ala Gly Ala Pro Arg Cys Thr Tyr Thr Phe Val Leu Pro Pro Gln 
1               5                   10                  15      


Lys Phe Thr Gly Ala Val Cys Trp Ser Gly Pro Ala Ser Thr Arg Ala 
            20                  25                  30          


Thr Pro Glu Ala Ala Asn Ala Ser Glu Leu Ala Ala Leu Arg Met Arg 
        35                  40                  45              


Val Gly Arg His Glu Glu Leu Leu Arg Glu Leu Gln Arg Leu Ala Ala 
    50                  55                  60                  


Ala Asp Gly Ala Val Ala Gly Glu Val Arg Ala Leu Arg Lys Glu Ser 
65                  70                  75                  80  


Arg Gly Leu Ser Ala Arg Leu Gly Gln Leu Arg Ala Gln Leu Gln His 
                85                  90                  95      


Glu Ala Gly Pro Gly Ala Gly Pro Gly Ala Asp Leu Gly Ala Glu Pro 
            100                 105                 110         


Ala Ala Ala Leu Ala Leu Leu Gly Glu Arg Val Leu Asn Ala Ser Ala 
        115                 120                 125             


Glu Ala Gln Arg Ala Ala Ala Arg Phe His Gln Leu Asp Val Lys Phe 
    130                 135                 140                 


Arg Glu Leu Ala Gln Leu Val Thr Gln Gln Ser Ser Leu Ile Ala Arg 
145                 150                 155                 160 


Leu Glu Arg Leu Cys Pro Gly Gly Ala Gly Gly Gln Gln Gln Val Leu 
                165                 170                 175     


Pro Pro Pro Pro Leu Val Pro Val Val Pro Val Arg Leu Val Gly Ser 
            180                 185                 190         


Thr Ser Asp Thr Ser Arg Met Leu Asp Pro Ala Pro Glu Pro Gln Arg 
        195                 200                 205             


Asp Gln Thr Gln Arg Gln Gln Glu Pro Met Ala Ser Pro Met Pro Ala 
    210                 215                 220                 


Gly His Pro Ala Val Pro Thr Lys Pro Val Gly Pro Trp Gln Asp Cys 
225                 230                 235                 240 


Ala Glu Ala Arg Gln Ala Gly His Glu Gln Ser Gly Val Tyr Glu Leu 
                245                 250                 255     


Arg Val Gly Arg His Val Val Ser Val Trp Cys Glu Gln Gln Leu Glu 
            260                 265                 270         


Gly Gly Gly Trp Thr Val Ile Gln Arg Arg Gln Asp Gly Ser Val Asn 
        275                 280                 285             


Phe Phe Thr Thr Trp Gln His Tyr Lys Ala Gly Phe Gly Arg Pro Asp 
    290                 295                 300                 


Gly Glu Tyr Trp Leu Gly Leu Glu Pro Val Tyr Gln Leu Thr Ser Arg 
305                 310                 315                 320 


Gly Asp His Glu Leu Leu Val Leu Leu Glu Asp Trp Gly Gly Arg Gly 
                325                 330                 335     


Ala Arg Ala His Tyr Asp Gly Phe Ser Leu Glu Pro Glu Ser Asp His 
            340                 345                 350         


Tyr Arg Leu Arg Leu Gly Gln Tyr His Gly Asp Ala Gly Asp Ser Leu 
        355                 360                 365             


Ser Trp His Asn Asp Lys Pro Phe Ser Thr Val Asp Arg Asp Arg Asp 
    370                 375                 380                 


Ser Tyr Ser Gly Asn Cys Ala Leu Tyr Gln Arg Gly Gly Trp Trp Tyr 
385                 390                 395                 400 


His Ala Cys Ala His Ser Asn Leu Asn Gly Val Trp His His Gly Gly 
                405                 410                 415     


His Tyr Arg Ser Arg Tyr Gln Asp Gly Val Tyr Trp Ala Glu Phe Arg 
            420                 425                 430         


Gly Gly Ala Tyr Ser Leu Arg Lys Ala Ala Met Leu Ile Arg Pro Leu 
        435                 440                 445             


Lys Leu 
    450 


<210>  1405
<211>  177
<212>  PRT
<213>  Homo Sapiens

<400>  1405

Ala Pro Met Gly Gly Pro Glu Leu Ala Gln His Glu Glu Leu Thr Leu 
1               5                   10                  15      


Leu Phe His Gly Thr Leu Gln Leu Gly Gln Ala Leu Asn Gly Val Tyr 
            20                  25                  30          


Arg Thr Thr Glu Gly Arg Leu Thr Lys Ala Arg Asn Ser Leu Gly Leu 
        35                  40                  45              


Tyr Gly Arg Thr Ile Glu Leu Leu Gly Gln Glu Val Ser Arg Gly Arg 
    50                  55                  60                  


Asp Ala Ala Gln Glu Leu Arg Ala Ser Leu Leu Glu Thr Gln Met Glu 
65                  70                  75                  80  


Glu Asp Ile Leu Gln Leu Gln Ala Glu Ala Thr Ala Glu Val Leu Gly 
                85                  90                  95      


Glu Val Ala Gln Ala Gln Lys Val Leu Arg Asp Ser Val Gln Arg Leu 
            100                 105                 110         


Glu Val Gln Leu Arg Ser Ala Trp Leu Gly Pro Ala Tyr Arg Glu Phe 
        115                 120                 125             


Glu Val Leu Lys Ala His Ala Asp Lys Gln Ser His Ile Leu Trp Ala 
    130                 135                 140                 


Leu Thr Gly His Val Gln Arg Gln Arg Arg Glu Met Val Ala Gln Gln 
145                 150                 155                 160 


His Arg Leu Arg Gln Ile Gln Glu Arg Leu His Thr Ala Ala Leu Pro 
                165                 170                 175     


Ala 
    


<210>  1406
<211>  338
<212>  PRT
<213>  Homo Sapiens

<400>  1406

Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp His 
1               5                   10                  15      


Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn Phe 
            20                  25                  30          


Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr Lys 
        35                  40                  45              


Gly Val Asp Glu Val Thr Ile Val Asn Ile Val Thr Asn Arg Asp Asn 
    50                  55                  60                  


Ala Gln Arg Gln Asp Ile Val Phe Ser Tyr Gln Arg Arg Thr Lys Lys 
65                  70                  75                  80  


Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu Thr 
                85                  90                  95      


Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser Glu 
            100                 105                 110         


Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu Ile 
        115                 120                 125             


Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn Arg 
    130                 135                 140                 


Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile Ser 
145                 150                 155                 160 


Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys Gly 
                165                 170                 175     


Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp Gln 
            180                 185                 190         


Asp Ala Gln Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr Asp 
        195                 200                 205             


Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His Leu 
    210                 215                 220                 


Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met Leu 
225                 230                 235                 240 


Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe Leu 
                245                 250                 255     


Asn Leu Val Gln Arg Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp Gln 
            260                 265                 270         


Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu Ile 
        275                 280                 285             


Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg Ser 
    290                 295                 300                 


Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln Gln 
305                 310                 315                 320 


Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly Gly 
                325                 330                 335     


Asp Asp 
        


<210>  1407
<211>  541
<212>  PRT
<213>  Homo Sapiens

<400>  1407

Leu Ser Asn Gly His Thr Cys Val Gly Cys Val Leu Val Val Ser Val 
1               5                   10                  15      


Ile Glu Gln Leu Ala Gln Val His Asn Ser Thr Val Gln Ala Ser Met 
            20                  25                  30          


Glu Arg Leu Cys Ser Tyr Leu Pro Glu Lys Leu Phe Leu Lys Thr Thr 
        35                  40                  45              


Cys Tyr Leu Val Ile Asp Lys Phe Gly Ser Asp Ile Ile Lys Leu Leu 
    50                  55                  60                  


Ser Ala Asp Met Asn Ala Asp Val Val Cys His Thr Leu Glu Phe Cys 
65                  70                  75                  80  


Lys Gln Asn Thr Gly Gln Pro Leu Cys His Leu Tyr Pro Leu Pro Lys 
                85                  90                  95      


Glu Thr Trp Lys Phe Thr Leu Gln Lys Ala Arg Gln Ile Val Lys Lys 
            100                 105                 110         


Ser Pro Ile Leu Lys Tyr Ser Arg Ser Gly Ser Asp Ile Cys Ser Leu 
        115                 120                 125             


Pro Val Leu Ala Lys Ile Cys Gln Lys Ile Lys Leu Ala Met Glu Gln 
    130                 135                 140                 


Ser Val Pro Phe Lys Asp Val Asp Ser Asp Lys Tyr Ser Val Phe Pro 
145                 150                 155                 160 


Thr Leu Arg Gly Tyr His Trp Arg Gly Arg Asp Cys Asn Asp Ser Asp 
                165                 170                 175     


Glu Ser Val Tyr Pro Gly Arg Arg Pro Asn Asn Trp Asp Val His Gln 
            180                 185                 190         


Asp Ser Asn Cys Asn Gly Ile Trp Gly Val Asp Pro Lys Asp Gly Val 
        195                 200                 205             


Pro Tyr Glu Lys Lys Phe Cys Glu Gly Ser Gln Pro Arg Gly Ile Ile 
    210                 215                 220                 


Leu Leu Gly Asp Ser Ala Gly Ala His Phe His Ile Ser Pro Glu Trp 
225                 230                 235                 240 


Ile Thr Ala Ser Gln Met Ser Leu Asn Ser Phe Ile Asn Leu Pro Thr 
                245                 250                 255     


Ala Leu Thr Asn Glu Leu Asp Trp Pro Gln Leu Ser Gly Ala Thr Gly 
            260                 265                 270         


Phe Leu Asp Ser Thr Val Gly Ile Lys Glu Lys Ser Ile Tyr Leu Arg 
        275                 280                 285             


Leu Trp Lys Arg Asn His Cys Asn His Arg Asp Tyr Gln Asn Ile Ser 
    290                 295                 300                 


Arg Asn Gly Ala Ser Ser Arg Asn Leu Lys Lys Phe Ile Glu Ser Leu 
305                 310                 315                 320 


Ser Arg Asn Lys Val Leu Asp Tyr Pro Ala Ile Val Ile Tyr Ala Met 
                325                 330                 335     


Ile Gly Asn Asp Val Cys Ser Gly Lys Ser Asp Pro Val Pro Ala Met 
            340                 345                 350         


Thr Thr Pro Glu Lys Leu Tyr Ser Asn Val Met Gln Thr Leu Lys His 
        355                 360                 365             


Leu Asn Ser His Leu Pro Asn Gly Ser His Val Ile Leu Tyr Gly Leu 
    370                 375                 380                 


Pro Asp Gly Thr Phe Leu Trp Asp Asn Leu His Asn Arg Tyr His Pro 
385                 390                 395                 400 


Leu Gly Gln Leu Asn Lys Asp Met Thr Tyr Ala Gln Leu Tyr Ser Phe 
                405                 410                 415     


Leu Asn Cys Leu Gln Val Ser Pro Cys His Gly Trp Met Ser Ser Asn 
            420                 425                 430         


Lys Thr Leu Arg Thr Leu Thr Ser Glu Arg Ala Glu Gln Leu Ser Asn 
        435                 440                 445             


Thr Leu Lys Lys Ile Ala Ala Ser Glu Lys Phe Thr Asn Phe Asn Leu 
    450                 455                 460                 


Phe Tyr Met Asp Phe Ala Phe His Glu Ile Ile Gln Glu Trp Gln Lys 
465                 470                 475                 480 


Arg Gly Gly Gln Pro Trp Gln Leu Ile Glu Pro Val Asp Gly Phe His 
                485                 490                 495     


Pro Asn Glu Val Ala Leu Leu Leu Leu Ala Asp His Phe Trp Lys Lys 
            500                 505                 510         


Val Gln Leu Gln Trp Pro Gln Ile Leu Gly Lys Glu Asn Pro Phe Asn 
        515                 520                 525             


Pro Gln Ile Lys Gln Val Phe Gly Asp Gln Gly Gly His 
    530                 535                 540     


<210>  1408
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  1408

Glu Ala Gly Gly Ser Cys Leu Arg Trp Glu Pro His Cys Gln Gln Pro 
1               5                   10                  15      


Leu Pro Asp Arg Val Pro Ser Thr Ala Ile Leu Pro Pro Arg Leu Asn 
            20                  25                  30          


Gly Pro Trp Ile Ser Thr Gly Cys Glu Val Arg Pro Gly Pro Glu Phe 
        35                  40                  45              


Leu Thr Arg Ala Tyr Thr Phe Tyr Pro Ser Arg Leu Phe Arg Ala His 
    50                  55                  60                  


Gln Phe Tyr Tyr Glu Asp Pro Phe Cys Gly Glu Pro Ala His Ser Leu 
65                  70                  75                  80  


Leu Val Lys Gly Lys Val Arg Leu Arg Arg Ala Ser Trp Val Thr Arg 
                85                  90                  95      


Gly Ala Thr Glu Ala Asp Tyr His Leu His Lys Val Gly Ile Val Phe 
            100                 105                 110         


His Ser Arg Arg Ala Leu Val Asp Val Thr Gly Arg Leu Asn Gln Thr 
        115                 120                 125             


Arg Ala Gly Arg Asp Cys Ala Arg Arg Leu Pro Pro Ala Arg Ala Trp 
    130                 135                 140                 


Leu Pro Gly Ala Leu Tyr Glu Leu Arg Ser Ala Arg Ala Gln Gly Asp 
145                 150                 155                 160 


Cys Leu Glu Ala Leu Gly Leu Thr Met His Glu Leu Ser Leu Val Arg 
                165                 170                 175     


Val Gln Arg Arg Leu Gln Pro Gln Pro Arg Ala Ser Pro Arg Leu Val 
            180                 185                 190         


Glu Glu Leu Tyr Leu Gly Asp Ile His Thr Asp Pro Ala Glu Arg Arg 
        195                 200                 205             


His Tyr Arg Pro Thr Gly Tyr Gln Arg Pro Leu Gln Ser Ala Leu His 
    210                 215                 220                 


His Val Gln Pro Cys Pro Ala Cys Gly Leu Ile Ala Arg Ser Asp Val 
225                 230                 235                 240 


His His Pro Pro Val Leu Pro Pro Pro Leu Ala Leu Pro Leu His Leu 
                245                 250                 255     


Gly Gly Trp Trp Val Ser Ser Gly Cys Glu Val Arg Pro Ala Val Leu 
            260                 265                 270         


Phe Leu Thr Arg Leu Phe Thr Phe His Gly His Ser Arg Ser Trp Glu 
        275                 280                 285             


Gly Tyr Tyr His His Phe Ser Asp Pro Ala Cys Arg Gln Pro Thr Phe 
    290                 295                 300                 


Thr Val Tyr Ala Ala Gly Arg Tyr Thr Arg Gly Thr Pro Ser Thr Arg 
305                 310                 315                 320 


Val Arg Gly Gly Thr Glu Leu Val Phe Glu Val Thr Arg Ala His Val 
                325                 330                 335     


Thr Pro Met Asp Gln Val Thr Thr Ala Met Leu Asn Phe Ser Glu Pro 
            340                 345                 350         


Ser Ser Cys Gly Gly Ala Gly Ala Trp Ser Met Gly Thr Glu Arg Asp 
        355                 360                 365             


Val Thr Ala Thr Asn Gly Cys Leu Pro Leu Gly Ile Arg Leu Pro His 
    370                 375                 380                 


Val Glu Tyr Glu Leu Phe Lys Met Glu Gln Asp Pro Leu Gly Gln Ser 
385                 390                 395                 400 


Leu Leu Phe Ile Gly Gln Arg Pro Thr Asp Gly Ser Ser Pro Asp Thr 
                405                 410                 415     


Pro Glu Lys Arg Pro Thr Ser Tyr Gln Ala Pro Leu Val Leu Cys His 
            420                 425                 430         


Gly Glu Ala Pro Asp Phe Ser Arg Pro Pro Gln His Arg Pro Ser Leu 
        435                 440                 445             


Gln Lys His Pro Ser Thr Gly Gly 
    450                 455     


<210>  1409
<211>  376
<212>  PRT
<213>  Homo Sapiens

<400>  1409

Glu Val Ser Ala Asp Gln Val Ala Thr Val Met Trp Asp Tyr Phe Ser 
1               5                   10                  15      


Gln Leu Ser Asn Asn Ala Lys Glu Ala Val Glu His Leu Gln Lys Ser 
            20                  25                  30          


Glu Leu Thr Gln Gln Leu Asn Ala Leu Phe Gln Asp Lys Leu Gly Glu 
        35                  40                  45              


Val Asn Thr Tyr Ala Gly Asp Leu Gln Lys Lys Leu Val Pro Phe Ala 
    50                  55                  60                  


Thr Glu Leu His Glu Arg Leu Ala Lys Asp Ser Glu Lys Leu Lys Glu 
65                  70                  75                  80  


Glu Ile Gly Lys Glu Leu Glu Glu Leu Arg Ala Arg Leu Leu Pro His 
                85                  90                  95      


Ala Asn Glu Val Ser Gln Lys Ile Gly Asp Asn Leu Arg Glu Leu Gln 
            100                 105                 110         


Gln Arg Leu Glu Pro Tyr Ala Asp Gln Leu Arg Thr Gln Val Asn Thr 
        115                 120                 125             


Gln Ala Glu Gln Leu Arg Arg Gln Leu Thr Pro Tyr Ala Gln Arg Met 
    130                 135                 140                 


Glu Arg Val Leu Arg Glu Asn Ala Asp Ser Leu Gln Ala Ser Leu Arg 
145                 150                 155                 160 


Pro His Ala Asp Glu Leu Lys Ala Lys Ile Asp Gln Asn Val Glu Glu 
                165                 170                 175     


Leu Lys Gly Arg Leu Thr Pro Tyr Ala Asp Glu Phe Lys Val Lys Ile 
            180                 185                 190         


Asp Gln Thr Val Glu Glu Leu Arg Arg Ser Leu Ala Pro Tyr Ala Gln 
        195                 200                 205             


Asp Thr Gln Glu Lys Leu Asn His Gln Leu Glu Gly Leu Thr Phe Gln 
    210                 215                 220                 


Met Lys Lys Asn Ala Glu Glu Leu Lys Ala Arg Ile Ser Ala Ser Ala 
225                 230                 235                 240 


Glu Glu Leu Arg Gln Arg Leu Ala Pro Leu Ala Glu Asp Val Arg Gly 
                245                 250                 255     


Asn Leu Arg Gly Asn Thr Glu Gly Leu Gln Lys Ser Leu Ala Glu Leu 
            260                 265                 270         


Gly Gly His Leu Asp Gln Gln Val Glu Glu Phe Arg Arg Arg Val Glu 
        275                 280                 285             


Pro Tyr Gly Glu Asn Phe Asn Lys Ala Leu Val Gln Gln Met Glu Gln 
    290                 295                 300                 


Leu Arg Gln Lys Leu Gly Pro His Ala Gly Asp Val Glu Gly His Leu 
305                 310                 315                 320 


Ser Phe Leu Glu Lys Asp Leu Arg Asp Lys Val Asn Ser Phe Phe Ser 
                325                 330                 335     


Thr Phe Lys Glu Lys Glu Ser Gln Asp Lys Thr Leu Ser Leu Pro Glu 
            340                 345                 350         


Leu Glu Gln Gln Gln Glu Gln Gln Gln Glu Gln Gln Gln Glu Gln Val 
        355                 360                 365             


Gln Met Leu Ala Pro Leu Glu Ser 
    370                 375     


<210>  1410
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  1410

Ser Gly Ala Gly Ala Ser Arg Pro Pro His Leu Val Phe Leu Leu Ala 
1               5                   10                  15      


Asp Asp Leu Gly Trp Asn Asp Val Gly Phe His Gly Ser Arg Ile Arg 
            20                  25                  30          


Thr Pro His Leu Asp Ala Leu Ala Ala Gly Gly Val Leu Leu Asp Asn 
        35                  40                  45              


Tyr Tyr Thr Gln Pro Leu Cys Thr Pro Ser Arg Ser Gln Leu Leu Thr 
    50                  55                  60                  


Gly Arg Tyr Gln Ile Arg Thr Gly Leu Gln His Gln Ile Ile Trp Pro 
65                  70                  75                  80  


Cys Gln Pro Ser Cys Val Pro Leu Asp Glu Lys Leu Leu Pro Gln Leu 
                85                  90                  95      


Leu Lys Glu Ala Gly Tyr Thr Thr His Met Val Gly Lys Trp His Leu 
            100                 105                 110         


Gly Met Tyr Arg Lys Glu Cys Leu Pro Thr Arg Arg Gly Phe Asp Thr 
        115                 120                 125             


Tyr Phe Gly Tyr Leu Leu Gly Ser Glu Asp Tyr Tyr Ser His Glu Arg 
    130                 135                 140                 


Cys Thr Leu Ile Asp Ala Leu Asn Val Thr Arg Cys Ala Leu Asp Phe 
145                 150                 155                 160 


Arg Asp Gly Glu Glu Val Ala Thr Gly Tyr Lys Asn Met Tyr Ser Thr 
                165                 170                 175     


Asn Ile Phe Thr Lys Arg Ala Ile Ala Leu Ile Thr Asn His Pro Pro 
            180                 185                 190         


Glu Lys Pro Leu Phe Leu Tyr Leu Ala Leu Gln Ser Val His Glu Pro 
        195                 200                 205             


Leu Gln Val Pro Glu Glu Tyr Leu Lys Pro Tyr Asp Phe Ile Gln Asp 
    210                 215                 220                 


Lys Asn Arg His His Tyr Ala Gly Met Val Ser Leu Met Asp Glu Ala 
225                 230                 235                 240 


Val Gly Asn Val Thr Ala Ala Leu Lys Ser Ser Gly Leu Trp Asn Asn 
                245                 250                 255     


Thr Val Phe Ile Phe Ser Thr Asp Asn Gly Gly Gln Thr Leu Ala Gly 
            260                 265                 270         


Gly Asn Asn Trp Pro Leu Arg Gly Arg Lys Trp Ser Leu Trp Glu Gly 
        275                 280                 285             


Gly Val Arg Gly Val Gly Phe Val Ala Ser Pro Leu Leu Lys Gln Lys 
    290                 295                 300                 


Gly Val Lys Asn Arg Glu Leu Ile His Ile Ser Asp Trp Leu Pro Thr 
305                 310                 315                 320 


Leu Val Lys Leu Ala Arg Gly His Thr Asn Gly Thr Lys Pro Leu Asp 
                325                 330                 335     


Gly Phe Asp Val Trp Lys Thr Ile Ser Glu Gly Ser Pro Ser Pro Arg 
            340                 345                 350         


Ile Glu Leu Leu His Asn Ile Asp Pro Asn Phe Val Asp Ser Ser Pro 
        355                 360                 365             


Cys Pro Arg Asn Ser Met Ala Pro Ala Lys Asp Asp Ser Ser Leu Pro 
    370                 375                 380                 


Glu Tyr Ser Ala Phe Asn Thr Ser Val His Ala Ala Ile Arg His Gly 
385                 390                 395                 400 


Asn Trp Lys Leu Leu Thr Gly Tyr Pro Gly Cys Gly Tyr Trp Phe Pro 
                405                 410                 415     


Pro Pro Ser Gln Tyr Asn Val Ser Glu Ile Pro Ser Ser Asp Pro Pro 
            420                 425                 430         


Thr Lys Thr Leu Trp Leu Phe Asp Ile Asp Arg Asp Pro Glu Glu Arg 
        435                 440                 445             


His Asp Leu Ser Arg Glu Tyr Pro His Ile Val Thr Lys Leu Leu Ser 
    450                 455                 460                 


Arg Leu Gln Phe Tyr His Lys His Ser Val Pro Val Tyr Phe Pro Ala 
465                 470                 475                 480 


Gln Asp Pro Arg Cys Asp Pro Lys Ala Thr Gly Val Trp Gly Pro Trp 
                485                 490                 495     


Met 
    


<210>  1411
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  1411

Ala Gly Gly Pro Gly Ser Arg Ala Arg Ala Ala Gly Ala Arg Gly Cys 
1               5                   10                  15      


Arg Leu Arg Ser Gln Leu Val Pro Val Arg Ala Leu Gly Leu Gly His 
            20                  25                  30          


Arg Ser Asp Glu Leu Val Arg Phe Arg Phe Cys Ser Gly Ser Cys Arg 
        35                  40                  45              


Arg Ala Arg Ser Pro His Asp Leu Ser Leu Ala Ser Leu Leu Gly Ala 
    50                  55                  60                  


Gly Ala Leu Arg Pro Pro Pro Gly Ser Arg Pro Val Ser Gln Pro Cys 
65                  70                  75                  80  


Cys Arg Pro Thr Arg Tyr Glu Ala Val Ser Phe Met Asp Val Asn Ser 
                85                  90                  95      


Thr Trp Arg Thr Val Asp Arg Leu Ser Ala Thr Ala Cys Gly Cys Leu 
            100                 105                 110         


Gly 
    


<210>  1412
<211>  369
<212>  PRT
<213>  Homo Sapiens

<400>  1412

Glu Ser Ser Glu Arg Val Ser Tyr Tyr Phe Ser Tyr Gln His Val Thr 
1               5                   10                  15      


Lys Val Asp Glu Val Val Ala Gln Ser Leu Val Phe Pro Ala Val Thr 
            20                  25                  30          


Leu Cys Asn Leu Asn Gly Phe Arg Phe Ser Arg Leu Thr Thr Asn Asp 
        35                  40                  45              


Leu Tyr His Ala Gly Glu Leu Leu Ala Leu Leu Asp Val Asn Leu Gln 
    50                  55                  60                  


Ile Pro Asp Pro His Leu Ala Asp Pro Ser Val Leu Glu Ala Leu Arg 
65                  70                  75                  80  


Gln Lys Ala Asn Phe Lys His Tyr Lys Pro Lys Gln Phe Ser Met Leu 
                85                  90                  95      


Glu Phe Leu His Arg Val Gly His Asp Leu Lys Asp Met Met Leu Tyr 
            100                 105                 110         


Cys Lys Phe Lys Gly Gln Glu Cys Gly His Gln Asp Phe Thr Thr Val 
        115                 120                 125             


Phe Thr Lys Tyr Gly Lys Cys Tyr Met Phe Asn Ser Gly Glu Asp Gly 
    130                 135                 140                 


Lys Pro Leu Leu Thr Thr Val Lys Gly Gly Thr Gly Asn Gly Leu Glu 
145                 150                 155                 160 


Ile Met Leu Asp Ile Gln Gln Asp Glu Tyr Leu Pro Ile Trp Gly Glu 
                165                 170                 175     


Thr Glu Glu Thr Thr Phe Glu Ala Gly Val Lys Val Gln Ile His Ser 
            180                 185                 190         


Gln Ser Glu Pro Pro Phe Ile Gln Glu Leu Gly Phe Gly Val Ala Pro 
        195                 200                 205             


Gly Phe Gln Thr Phe Val Ala Thr Gln Glu Gln Arg Leu Thr Tyr Leu 
    210                 215                 220                 


Pro Pro Pro Trp Gly Glu Cys Arg Ser Ser Glu Met Gly Leu Asp Phe 
225                 230                 235                 240 


Phe Pro Val Tyr Ser Ile Thr Ala Cys Arg Ile Asp Cys Glu Thr Arg 
                245                 250                 255     


Tyr Ile Val Glu Asn Cys Asn Cys Arg Met Val His Met Pro Gly Asp 
            260                 265                 270         


Ala Pro Phe Cys Thr Pro Glu Gln His Lys Glu Cys Ala Glu Pro Ala 
        275                 280                 285             


Leu Gly Leu Leu Ala Glu Lys Asp Ser Asn Tyr Cys Leu Cys Arg Thr 
    290                 295                 300                 


Pro Cys Asn Leu Thr Arg Tyr Asn Lys Glu Leu Ser Met Val Lys Ile 
305                 310                 315                 320 


Pro Ser Lys Thr Ser Ala Lys Tyr Leu Glu Lys Lys Phe Asn Lys Ser 
                325                 330                 335     


Glu Lys Tyr Ile Ser Glu Asn Ile Leu Val Leu Asp Ile Phe Phe Glu 
            340                 345                 350         


Ala Leu Asn Tyr Glu Thr Ile Glu Gln Lys Lys Ala Tyr Glu Val Ala 
        355                 360                 365             


Ala 
    


<210>  1413
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  1413

Arg Leu Met Lys Glu Glu Ser Pro Val Val Ser Trp Arg Leu Glu Pro 
1               5                   10                  15      


Glu Asp Gly Thr Ala Leu Asp Val His Phe Val Ser Thr Leu Glu Pro 
            20                  25                  30          


Leu Ser Asn Ala Val Lys Arg Asn Val Pro Arg Cys Ile Ile Ile Leu 
        35                  40                  45              


Val Leu Gln Glu Pro Thr Ala Phe Arg Ile Ser Val Thr Ser Ser Cys 
    50                  55                  60                  


Phe Val Gln Asn Thr Leu Thr Lys Leu Leu Lys Asp Arg Arg Lys Met 
65                  70                  75                  80  


Gln Thr Val Gln Cys Ala Thr Ala Arg Glu Thr Ser 
                85                  90          


<210>  1414
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  1414

Arg Leu Met Lys Glu Glu Ser Pro Val Val Ser Trp Arg Leu Glu Pro 
1               5                   10                  15      


Glu Asp Gly Thr Ala Leu Asp Val His Phe Val Ser Thr Leu Glu Pro 
            20                  25                  30          


Leu Ser Asn Ala Val Lys Arg Asn Val Pro Arg Cys Ile Ile Ile Leu 
        35                  40                  45              


Val Leu Gln Glu Pro Thr Pro Phe Arg Ile Ser Val Thr Ser Ser Cys 
    50                  55                  60                  


Phe Val Gln Asn Thr Leu Thr Lys Leu Leu Lys Asp Arg Arg Lys Met 
65                  70                  75                  80  


Gln Thr Val Gln Cys Ala Thr Ala Gln Glu Thr Ser 
                85                  90          


<210>  1415
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1415

His Ser Asp Pro Ala Arg Arg Gly Glu Leu Ser Val Cys Asp Ser Ile 
1               5                   10                  15      


Ser Glu Trp Val Thr Ala Ala Asp Lys Lys Thr Ala Val Asp Met Ser 
            20                  25                  30          


Gly Gly Thr Val Thr Val Leu Glu Lys Val Pro Val Ser Lys Gly Gln 
        35                  40                  45              


Leu Lys Gln Tyr Phe Tyr Glu Thr Lys Cys Asn Pro Met Gly Tyr Thr 
    50                  55                  60                  


Lys Glu Gly Cys Arg Gly Ile Asp Lys Arg His Trp Asn Ser Gln Cys 
65                  70                  75                  80  


Arg Thr Thr Gln Ser Tyr Val Arg Ala Leu Thr Met Asp Ser Lys Lys 
                85                  90                  95      


Arg Ile Gly Trp Arg Phe Ile Arg Ile Asp Thr Ser Cys Val Cys Thr 
            100                 105                 110         


Leu Thr Ile Lys Arg Gly Arg 
        115                 


<210>  1416
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  1416

Ser Ala Ser Ser Arg Arg Arg Gln Gln Ser Arg Asn Arg Ser Thr Gln 
1               5                   10                  15      


Ser Gln Asp Val Ala Arg Val Ser Ser Ala Ser Asp Tyr Asn Ser Ser 
            20                  25                  30          


Glu Leu Lys Thr Ala Cys Arg Lys His Glu Leu Tyr Val Ser Phe Gln 
        35                  40                  45              


Asp Leu Gly Trp Gln Asp Trp Ile Ile Ala Pro Lys Gly Tyr Ala Ala 
    50                  55                  60                  


Asn Tyr Cys Asp Gly Glu Cys Ser Phe Pro Leu Asn Ala His Met Asn 
65                  70                  75                  80  


Ala Thr Asn His Ala Ile Val Gln Thr Leu Val His Leu Met Asn Pro 
                85                  90                  95      


Glu Tyr Val Pro Lys Pro Cys Cys Ala Pro Thr Lys Leu Asn Ala Ile 
            100                 105                 110         


Ser Val Leu Tyr Phe Asp Asp Asn Ser Asn Val Ile Leu Lys Lys Tyr 
        115                 120                 125             


Arg Asn Met Val Val Arg Ala Cys Gly Cys His 
    130                 135                 


<210>  1417
<211>  233
<212>  PRT
<213>  Homo Sapiens

<400>  1417

His Lys Gln Pro Trp Pro Gly Leu Ala Gln Ala His Arg Asp Asn Lys 
1               5                   10                  15      


Ser Thr Leu Ala Arg Ile Ile Ala Gln Gly Leu Ile Lys His Asn Ala 
            20                  25                  30          


Glu Ser Arg Ile Gln Asn Ile His Phe Gly Asp Arg Leu Asn Ala Ser 
        35                  40                  45              


Ala Gln Val Ala Pro Gly Leu Val Gly Trp Leu Ile Ser Gly Arg Lys 
    50                  55                  60                  


His Gln Gln Gln Gln Glu Ser Ser Ile Asn Ile Thr Asn Ile Gln Leu 
65                  70                  75                  80  


Asp Cys Gly Gly Ile Gln Ile Ser Phe His Lys Glu Trp Phe Ser Ala 
                85                  90                  95      


Asn Ile Ser Leu Glu Phe Asp Leu Glu Leu Arg Pro Ser Phe Asp Asn 
            100                 105                 110         


Asn Ile Val Lys Met Cys Ala His Met Ser Ile Val Val Glu Phe Trp 
        115                 120                 125             


Leu Glu Lys Asp Glu Phe Gly Arg Arg Asp Leu Val Ile Gly Lys Cys 
    130                 135                 140                 


Asp Ala Glu Pro Ser Ser Val His Val Ala Ile Leu Thr Glu Ala Ile 
145                 150                 155                 160 


Pro Pro Lys Met Asn Gln Phe Leu Tyr Asn Leu Lys Glu Asn Leu Gln 
                165                 170                 175     


Lys Val Leu Pro His Met Val Glu Ser Gln Val Cys Pro Leu Ile Gly 
            180                 185                 190         


Glu Ile Leu Gly Gln Leu Asp Val Lys Leu Leu Lys Ser Leu Ile Glu 
        195                 200                 205             


Gln Glu Ala Ala His Glu Pro Thr His His Glu Thr Ser Gln Pro Ser 
    210                 215                 220                 


Ala Cys Gln Ala Gly Glu Ser Pro Ser 
225                 230             


<210>  1418
<211>  159
<212>  PRT
<213>  Homo Sapiens

<400>  1418

Gln Glu Val Leu Ala Gly Val Ser Ser Gln Leu Leu Asn Asp Leu Thr 
1               5                   10                  15      


Gln Gly Leu Leu Arg Ala Asp Phe Leu Pro Ser Leu Gln Thr Thr Gly 
            20                  25                  30          


Leu Gln Lys Pro Leu Ser Ser Ala Phe Asp Gly Val Ser Gly Leu Leu 
        35                  40                  45              


Asp Ile Phe Gly Pro Pro Leu Thr Asn Glu Ile Asn Thr Val Ser Ile 
    50                  55                  60                  


Gln Val Lys Asn Pro Gln Leu Leu His Val Ser Ile Glu Ser Thr Pro 
65                  70                  75                  80  


Gln Arg Lys Glu Ala Thr Val Gln Val Pro Phe Thr Ser Glu Leu Ile 
                85                  90                  95      


Val Gln Leu Leu Thr Met Lys Pro Phe Thr Ala Asn Met Gln Ser Asp 
            100                 105                 110         


Ile Lys Val Gln Ile Arg Leu Glu Lys Asn Val Gly Gly Arg Tyr Glu 
        115                 120                 125             


Leu Ala Phe Gly Asn Cys Arg Leu Leu Pro Glu Ala Ile Trp Ile Gln 
    130                 135                 140                 


Thr Gly Val Gln Leu Ala Pro Ala Gln Asn Leu Leu Trp Gln Thr 
145                 150                 155                 


<210>  1419
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  1419

Gln Thr Ile Tyr Pro Gly Ile Lys Ala Arg Ile Thr Gln Arg Ala Leu 
1               5                   10                  15      


Asp Tyr Gly Val Gln Ala Gly Met Lys Met Ile Glu Gln Met Leu Lys 
            20                  25                  30          


Glu Lys Lys Leu Pro Asp Leu Ser Gly Ser Glu Ser Leu Glu Phe Leu 
        35                  40                  45              


Lys Val Asp Tyr Val Asn Tyr Asn Phe Ser Asn Ile Lys Ile Ser Ala 
    50                  55                  60                  


Phe Ser Phe Pro Asn Thr Ser Leu Ala Phe Val Pro Gly Val Gly Ile 
65                  70                  75                  80  


Lys Ala Leu Thr Asn His Gly Thr Ala Asn Ile Ser Thr Asp Trp Gly 
                85                  90                  95      


Phe Glu Ser Pro Leu Phe Gln Asp Thr Gly Gly Ala Asp Leu Phe Leu 
            100                 105                 110         


Ser Gly Val Tyr Phe Thr Gly Ile Ile Ile Leu Thr Arg Asn Asp Phe 
        115                 120                 125             


Gly His Pro Thr Leu Lys Leu Gln Asp Cys Tyr Ala Gln Leu Ser His 
    130                 135                 140                 


Ala His Val Ser Phe Ser Gly Glu Leu Ser Val Leu Tyr Asn Ser Phe 
145                 150                 155                 160 


Ala Glu Pro Met Glu Lys Pro Ile Leu Lys Asn Leu Asn Glu Met Leu 
                165                 170                 175     


Cys Pro Ile Ile Ala Ser Glu Val Lys Ala Leu Asn Ala Asn Leu Ser 
            180                 185                 190         


Thr Leu Glu Val Leu Thr Lys Ile Asp Asn Tyr Thr Leu Leu Asp Tyr 
        195                 200                 205             


Ser Leu Ile Ser Ser Pro Glu Ile Thr Glu Asn Tyr Leu Asp Leu Asn 
    210                 215                 220                 


Leu Lys Gly Val Phe Tyr Pro Leu Glu Asn Leu Thr Asp Pro Pro Phe 
225                 230                 235                 240 


Ser Pro Val Pro Phe Val Leu Pro Glu Arg Ser Asn Ser Met Leu Tyr 
                245                 250                 255     


Ile Gly Ile Ala Glu Tyr Phe Phe Lys Ser Ala Ser Phe Ala His Phe 
            260                 265                 270         


Thr Ala Gly Val Phe Asn Val Thr Leu Ser Thr Glu Glu Ile Ser Asn 
        275                 280                 285             


His Phe Val Gln Asn Ser Gln Gly Leu Gly Asn Val Leu Ser Arg Ile 
    290                 295                 300                 


Ala Glu Ile Tyr Ile Leu Ser Gln Pro Phe Met Val Arg Ile Met Ala 
305                 310                 315                 320 


Thr Glu Pro Pro Ile Ile Asn Leu Gln Pro Gly Asn Phe Thr Leu Asp 
                325                 330                 335     


Ile Pro Ala Ser Ile Met Met Leu Thr Gln Pro Lys Asn Ser Thr Val 
            340                 345                 350         


Glu Thr Ile Val Ser Met Asp Phe Val Ala Ser Thr Ser Val Gly Leu 
        355                 360                 365             


Val Ile Leu Gly Gln Arg Leu Val Cys Ser Leu Ser Leu Asn Arg Phe 
    370                 375                 380                 


Arg Leu Ala Leu Pro Glu Ser Asn Arg Ser Asn Ile Glu Val Leu Arg 
385                 390                 395                 400 


Phe Glu Asn Ile Leu Ser Ser Ile Leu His Phe Gly Val Leu Pro Leu 
                405                 410                 415     


Ala Asn Ala Lys Leu Gln Gln Gly Phe Pro Leu Ser Asn Pro His Lys 
            420                 425                 430         


Phe Leu Phe Val Asn Ser Asp Ile Glu Val Leu Glu Gly Phe Leu Leu 
        435                 440                 445             


Ile Ser Thr Asp Leu Lys Tyr Glu Thr Ser Ser Lys Gln Gln Pro Ser 
    450                 455                 460                 


Phe His Val Trp Glu Gly Leu Asn Leu Ile Ser Arg Gln Trp Arg Gly 
465                 470                 475                 480 


Lys Ser Ala Pro 
                


<210>  1420
<211>  450
<212>  PRT
<213>  Homo Sapiens

<400>  1420

Ala Gln Arg Ala Asp Val Gly Gly Glu Ala Ala Gly Thr Ser Ile Asn 
1               5                   10                  15      


His Ser Gln Ala Val Leu Gln Arg Leu Gln Glu Leu Leu Arg Gln Gly 
            20                  25                  30          


Asn Ala Ser Asp Val Val Leu Arg Val Gln Ala Ala Gly Thr Asp Glu 
        35                  40                  45              


Val Arg Val Phe His Ala His Arg Leu Leu Leu Gly Leu His Ser Glu 
    50                  55                  60                  


Leu Phe Leu Glu Leu Leu Ser Asn Gln Ser Glu Ala Val Leu Gln Glu 
65                  70                  75                  80  


Pro Gln Asp Cys Ala Ala Val Phe Asp Lys Phe Ile Arg Tyr Leu Tyr 
                85                  90                  95      


Cys Gly Glu Leu Thr Val Leu Leu Thr Gln Ala Ile Pro Leu His Arg 
            100                 105                 110         


Leu Ala Thr Lys Tyr Gly Val Ser Ser Leu Gln Arg Gly Val Ala Asp 
        115                 120                 125             


Tyr Met Arg Ala His Leu Ala Gly Gly Ala Gly Pro Ala Val Gly Trp 
    130                 135                 140                 


Tyr His Tyr Ala Val Gly Thr Gly Asp Glu Ala Leu Arg Glu Ser Cys 
145                 150                 155                 160 


Leu Gln Phe Leu Ala Trp Asn Leu Ser Ala Val Ala Ala Ser Thr Glu 
                165                 170                 175     


Trp Gly Ala Val Ser Pro Glu Leu Leu Trp Gln Leu Leu Gln Arg Ser 
            180                 185                 190         


Asp Leu Val Leu Gln Asp Glu Leu Glu Leu Phe His Ala Leu Glu Ala 
        195                 200                 205             


Trp Leu Gly Arg Ala Arg Pro Pro Pro Ala Val Ala Glu Arg Ala Leu 
    210                 215                 220                 


Arg Ala Ile Arg Tyr Pro Met Ile Pro Pro Ala Gln Leu Phe Gln Leu 
225                 230                 235                 240 


Gln Ala Arg Ser Ala Ala Leu Ala Arg His Gly Pro Ala Val Ala Asp 
                245                 250                 255     


Leu Leu Leu Gln Ala Tyr Gln Phe His Ala Ala Ser Pro Leu His Tyr 
            260                 265                 270         


Ala Lys Phe Phe Asp Val Asn Gly Ser Ala Phe Leu Pro Arg Asn Tyr 
        275                 280                 285             


Leu Ala Pro Ala Trp Gly Ala Pro Trp Val Ile Asn Asn Pro Ala Arg 
    290                 295                 300                 


Asp Asp Arg Ser Thr Ser Phe Gln Thr Gln Leu Gly Pro Ser Gly His 
305                 310                 315                 320 


Asp Ala Gly Arg Arg Val Thr Trp Asn Val Leu Phe Ser Pro Arg Trp 
                325                 330                 335     


Leu Pro Val Ser Leu Arg Pro Val Tyr Ala Asp Ala Ala Gly Thr Ala 
            340                 345                 350         


Leu Pro Ala Ala Arg Pro Glu Asp Gly Arg Pro Arg Leu Val Val Thr 
        355                 360                 365             


Pro Ala Ser Ser Gly Gly Asp Ala Ala Gly Val Ser Phe Gln Lys Thr 
    370                 375                 380                 


Val Leu Val Gly Ala Arg Gln Gln Gly Arg Leu Leu Val Arg His Ala 
385                 390                 395                 400 


Tyr Ser Phe His Gln Ser Ser Glu Glu Ala Gly Asp Phe Leu Ala His 
                405                 410                 415     


Ala Asp Leu Gln Arg Arg Asn Ser Glu Tyr Leu Val Glu Asn Ala Leu 
            420                 425                 430         


His Leu His Leu Ile Val Lys Pro Val Tyr His Thr Leu Ile Arg Thr 
        435                 440                 445             


Pro Lys 
    450 


<210>  1421
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  1421

Gly Val Thr Gly Ala Trp Pro Thr Ser Gly Leu Ser Ile Leu Ala Gln 
1               5                   10                  15      


Leu Gln Pro Ser Cys Glu Leu Arg Trp Thr Gln Leu Ser Arg Ser Ser 
            20                  25                  30          


Trp Arg Asp Leu Val Met Thr Thr Ser Leu Trp Ser Leu Ala Tyr Phe 
        35                  40                  45              


Gln His Phe Ser Gln Glu Thr Thr Thr Gln Glu Gln Leu Asp Glu Met 
    50                  55                  60                  


Glu Glu Ile Pro Arg Glu Ser Gln Cys Gly Arg Gln Asp Phe His Ala 
65                  70                  75                  80  


Leu Ser Cys Pro Thr Ala Ser Pro Arg Asp Arg Val Leu Leu Cys Cys 
                85                  90                  95      


Pro Gly Trp Arg Ala Met Val Pro Ser 
            100                 105 


<210>  1422
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  1422

Gln Pro Leu Arg Ser Gln Arg Ser Val Pro Glu Ala Phe Ser Ala Pro 
1               5                   10                  15      


Leu Glu Leu Ser Gln Pro Leu Ser Gly Leu Val Asp Asp Tyr Gly Ile 
            20                  25                  30          


Leu Pro Lys His Pro Arg Pro Arg Gly Pro Arg Pro Leu Leu Ser Arg 
        35                  40                  45              


Ala Gln Gln Arg Lys Arg Asp Gly Pro Asp Leu Ala Glu Tyr Tyr Tyr 
    50                  55                  60                  


Asp Ala His Leu 
65              


<210>  1423
<211>  521
<212>  PRT
<213>  Homo Sapiens

<400>  1423

Arg Cys Cys Cys Cys Ala Cys Lys Ser Glu Thr Asn Gly Gly Asn Thr 
1               5                   10                  15      


Gly Ser Gln Gly Gly Asn Pro Pro Pro Ser Thr Pro Ile Thr Val Thr 
            20                  25                  30          


Gly His Gly Leu Ala Val Gln Ser Ser Glu Gln Leu Leu His Val Ile 
        35                  40                  45              


Tyr Gln Arg Val Asp Lys Ala Val Gly Leu Ala Glu Ala Ala Leu Gly 
    50                  55                  60                  


Leu Ala Arg Ala Asn Asn Glu Leu Leu Lys Arg Leu Gln Glu Glu Val 
65                  70                  75                  80  


Gly Asp Leu Arg Gln Gly Lys Val Ser Ile Pro Asp Glu Asp Gly Glu 
                85                  90                  95      


Ser Arg Ala His Ser Ser Pro Pro Glu Glu Pro Gly Pro Leu Lys Glu 
            100                 105                 110         


Ser Pro Gly Glu Ala Phe Lys Ala Leu Ser Ala Val Glu Glu Glu Cys 
        115                 120                 125             


Asp Ser Val Gly Ser Gly Val Gln Val Val Ile Glu Glu Leu Arg Gln 
    130                 135                 140                 


Leu Gly Ala Ala Ser Val Gly Pro Gly Pro Leu Gly Phe Pro Ala Thr 
145                 150                 155                 160 


Gln Arg Asp Met Arg Leu Pro Gly Cys Thr Leu Ala Ala Ser Glu Ala 
                165                 170                 175     


Ala Pro Leu Leu Asn Pro Leu Val Asp Asp Tyr Val Ala Ser Glu Gly 
            180                 185                 190         


Ala Val Gln Arg Val Leu Val Pro Ala Tyr Ala Lys Gln Leu Ser Pro 
        195                 200                 205             


Ala Thr Gln Leu Ala Ile Gln Arg Ala Thr Pro Glu Thr Gly Pro Glu 
    210                 215                 220                 


Asn Gly Thr Lys Leu Pro Pro Pro Arg Pro Glu Asp Met Leu Asn Ala 
225                 230                 235                 240 


Ala Ala Ala Leu Asp Ser Ala Leu Glu Glu Ser Gly Pro Gly Ser Thr 
                245                 250                 255     


Gly Glu Leu Arg His Ser Leu Gly Leu Thr Val Ser Pro Cys Arg Thr 
            260                 265                 270         


Arg Gly Ser Gly Gln Lys Asn Ser Arg Arg Lys Arg Asp Leu Val Leu 
        275                 280                 285             


Ser Lys Leu Val His Asn Val His Asn His Ile Thr Asn Asp Lys Arg 
    290                 295                 300                 


Phe Asn Gly Ser Glu Ser Ile Lys Ser Ser Trp Asn Ile Ser Val Val 
305                 310                 315                 320 


Lys Phe Leu Leu Glu Lys Leu Lys Gln Glu Leu Val Thr Ser Pro His 
                325                 330                 335     


Asn Tyr Thr Asp Lys Glu Leu Lys Gly Ala Cys Val Ala Tyr Phe Leu 
            340                 345                 350         


Thr Lys Arg Arg Glu Tyr Arg Asn Ser Leu Asn Pro Phe Lys Gly Leu 
        355                 360                 365             


Lys Glu Lys Glu Glu Lys Lys Leu Arg Ser Arg Arg Tyr Arg Leu Phe 
    370                 375                 380                 


Ala Asn Arg Ser Ser Ile Met Arg His Phe Gly Pro Glu Asp Gln Arg 
385                 390                 395                 400 


Leu Trp Asn Asp Val Thr Glu Glu Leu Met Ser Asp Glu Glu Asp Ser 
                405                 410                 415     


Leu Asn Glu Pro Gly Val Trp Val Ala Arg Pro Pro Arg Phe Arg Ala 
            420                 425                 430         


Gln Arg Leu Thr Glu Leu Cys Tyr His Leu Asp Ala Asn Ser Lys His 
        435                 440                 445             


Gly Thr Lys Ala Asn Arg Val Tyr Gly Pro Pro Ser Asp Arg Leu Pro 
    450                 455                 460                 


Ser Ala Glu Ala Gln Leu Leu Pro Pro Glu Leu Tyr Asn Pro Asn Phe 
465                 470                 475                 480 


Gln Glu Glu Glu Asp Glu Gly Gly Asp Glu Asn Ala Pro Gly Ser Pro 
                485                 490                 495     


Ser Phe Asp Gln Pro His Lys Thr Cys Cys Pro Asp Leu Asn Ser Phe 
            500                 505                 510         


Ile Glu Ile Lys Val Glu Lys Asp Glu 
        515                 520     


<210>  1424
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  1424

Arg Pro Lys Pro Ser Ala Ser Glu Val Leu Thr Arg His Leu Leu Gln 
1               5                   10                  15      


Arg Arg Leu Pro His Trp Thr Ser Phe Cys Val Pro Tyr Ser Ala Val 
            20                  25                  30          


Arg Asn Asp Gln Phe Gly Leu Ser His Phe Asn Trp Pro Val Gln Gly 
        35                  40                  45              


Ala Asn Tyr His Val Leu Arg Thr Gly Cys Phe Pro Phe Ile Lys Tyr 
    50                  55                  60                  


His Cys Ser Lys Ala Pro Trp Gln Asp Leu Ala Arg Gln Asn Arg Phe 
65                  70                  75                  80  


Phe Thr Ala Leu Lys Val Val Asn Leu Gly Ile Pro Thr Leu Leu Tyr 
                85                  90                  95      


Gly Leu Gly Ser Trp Leu Phe Ala Arg Val Thr Glu Thr Val His Thr 
            100                 105                 110         


Ser Tyr Gly Pro Ile Thr Val Tyr Phe Leu Asn Lys Glu Asp Glu Gly 
        115                 120                 125             


Ala Met Tyr 
    130     


<210>  1425
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  1425

Lys Ser Met Glu Asn Thr Val Thr Arg Asn Ser Thr Ala Val Ile Asn 
1               5                   10                  15      


Thr Gln Ala Glu Gly Thr Leu Ser Pro Pro Gly Leu Ser Ser Leu Pro 
            20                  25                  30          


Val Val Arg Glu Trp Ala Leu Thr His Thr Ala Gln Leu Pro Glu Cys 
        35                  40                  45              


Cys Val Asp Val Val Gly Val Asn Ala Ser Cys Pro Gly Ala Ser Leu 
    50                  55                  60                  


Cys Gly Pro Gly Cys Tyr Arg Arg Trp Asn Ala Asp Gly Ser Ala Ser 
65                  70                  75                  80  


Cys Val Arg Cys Gly Asn Gly Thr Leu Pro Ala Tyr Asn Gly Ser Glu 
                85                  90                  95      


Cys Arg Ser Phe Ala Gly Pro Gly Ala Pro Phe Pro Met Asn Arg Ser 
            100                 105                 110         


Ser Gly Thr Pro Gly Arg Pro His Pro Gly Ala Pro Arg Val Ala Ala 
        115                 120                 125             


Ser 
    


<210>  1426
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  1426

Glu Asp Leu Cys Arg Ala Pro Asp Gly Lys Lys Gly Glu Ala Gly Arg 
1               5                   10                  15      


Pro Gly Arg Arg Gly Arg Pro Gly Leu Lys Gly Glu Gln Gly Glu Pro 
            20                  25                  30          


Gly Ala Pro Gly Ile Arg Thr Gly Ile Gln Gly Leu Lys Gly Asp Gln 
        35                  40                  45              


Gly Glu Pro Gly Pro Ser Gly Asn Pro Gly Lys Val Gly Tyr Pro Gly 
    50                  55                  60                  


Pro Ser Gly Pro Leu Gly Ala Arg Gly Ile Pro Gly Ile Lys Gly Thr 
65                  70                  75                  80  


Lys Gly Ser Pro Gly Asn Ile Lys Asp Gln Pro Arg Pro Ala Phe Ser 
                85                  90                  95      


Ala Ile Arg Arg Asn Pro Pro Met Gly Gly Asn Val Val Ile Phe Asp 
            100                 105                 110         


Thr Val Ile Thr Asn Gln Glu Glu Pro Tyr Gln Asn His Ser Gly Arg 
        115                 120                 125             


Phe Val Cys Thr Val Pro Gly Tyr Tyr Tyr Phe Thr Phe Gln Val Leu 
    130                 135                 140                 


Ser Gln Trp Glu Ile Cys Leu Ser Ile Val Ser Ser Ser Arg Gly Gln 
145                 150                 155                 160 


Val Arg Arg Ser Leu Gly Phe Cys Asp Thr Thr Asn Lys Gly Leu Phe 
                165                 170                 175     


Gln Val Val Ser Gly Gly Met Val Leu Gln Leu Gln Gln Gly Asp Gln 
            180                 185                 190         


Val Trp Val Glu Lys Asp Pro Lys Lys Gly His Ile Tyr Gln Gly Ser 
        195                 200                 205             


Glu Ala Asp Ser Val Phe Ser Gly Phe Leu Ile Phe Pro Ser Ala 
    210                 215                 220             


<210>  1427
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  1427

Gln Leu Ser Cys Thr Gly Pro Pro Ala Ile Pro Gly Ile Pro Gly Ile 
1               5                   10                  15      


Pro Gly Thr Pro Gly Pro Asp Gly Gln Pro Gly Thr Pro Gly Ile Lys 
            20                  25                  30          


Gly Glu Lys Gly Leu Pro Gly Leu Ala Gly Asp His Gly Glu Phe Gly 
        35                  40                  45              


Glu Lys Gly Asp Pro Gly Ile Pro Gly Asn Pro Gly Lys Val Gly Pro 
    50                  55                  60                  


Lys Gly Pro Met Gly Pro Lys Gly Gly Pro Gly Ala Pro Gly Ala Pro 
65                  70                  75                  80  


Gly Pro Lys Gly Glu Ser Gly Asp Tyr Lys Ala Thr Gln Lys Ile Ala 
                85                  90                  95      


Phe Ser Ala Thr Arg Thr Ile Asn Val Pro Leu Arg Arg Asp Gln Thr 
            100                 105                 110         


Ile Arg Phe Asp His Val Ile Thr Asn Met Asn Asn Asn Tyr Glu Pro 
        115                 120                 125             


Arg Ser Gly Lys Phe Thr Cys Lys Val Pro Gly Leu Tyr Tyr Phe Thr 
    130                 135                 140                 


Tyr His Ala Ser Ser Arg Gly Asn Leu Cys Val Asn Leu Met Arg Gly 
145                 150                 155                 160 


Arg Glu Arg Ala Gln Lys Val Val Thr Phe Cys Asp Tyr Ala Tyr Asn 
                165                 170                 175     


Thr Phe Gln Val Thr Thr Gly Gly Met Val Leu Lys Leu Glu Gln Gly 
            180                 185                 190         


Glu Asn Val Phe Leu Gln Ala Thr Asp Lys Asn Ser Leu Leu Gly Met 
        195                 200                 205             


Glu Gly Ala Asn Ser Ile Phe Ser Gly Phe Leu Leu Phe Pro Asp Met 
    210                 215                 220                 


Glu Ala 
225     


<210>  1428
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  1428

Asn Thr Gly Cys Tyr Gly Ile Pro Gly Met Pro Gly Leu Pro Gly Ala 
1               5                   10                  15      


Pro Gly Lys Asp Gly Tyr Asp Gly Leu Pro Gly Pro Lys Gly Glu Pro 
            20                  25                  30          


Gly Ile Pro Ala Ile Pro Gly Ile Arg Gly Pro Lys Gly Gln Lys Gly 
        35                  40                  45              


Glu Pro Gly Leu Pro Gly His Pro Gly Lys Asn Gly Pro Met Gly Pro 
    50                  55                  60                  


Pro Gly Met Pro Gly Val Pro Gly Pro Met Gly Ile Pro Gly Glu Pro 
65                  70                  75                  80  


Gly Glu Glu Gly Arg Tyr Lys Gln Lys Phe Gln Ser Val Phe Thr Val 
                85                  90                  95      


Thr Arg Gln Thr His Gln Pro Pro Ala Pro Asn Ser Leu Ile Arg Phe 
            100                 105                 110         


Asn Ala Val Leu Thr Asn Pro Gln Gly Asp Tyr Asp Thr Ser Thr Gly 
        115                 120                 125             


Lys Phe Thr Cys Lys Val Pro Gly Leu Tyr Tyr Phe Val Tyr His Ala 
    130                 135                 140                 


Ser His Thr Ala Asn Leu Cys Val Leu Leu Tyr Arg Ser Gly Val Lys 
145                 150                 155                 160 


Val Val Thr Phe Cys Gly His Thr Ser Lys Thr Asn Gln Val Asn Ser 
                165                 170                 175     


Gly Gly Val Leu Leu Arg Leu Gln Val Gly Glu Glu Val Trp Leu Ala 
            180                 185                 190         


Val Asn Asp Tyr Tyr Asp Met Val Gly Ile Gln Gly Ser Asp Ser Val 
        195                 200                 205             


Phe Ser Gly Phe Leu Leu Phe Pro Asp 
    210                 215         


<210>  1429
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1429

His Tyr Glu Met Leu Gly Thr Cys Arg Met Val Cys Asp Pro Tyr Gly 
1               5                   10                  15      


Gly Thr Lys Ala Pro Ser Thr Ala Ala Thr Pro Asp Arg Gly Leu Met 
            20                  25                  30          


Gln Ser Leu Pro Thr Phe Ile Gln Gly Pro Lys Gly Glu Ala Gly Arg 
        35                  40                  45              


Pro Gly Lys Ala Gly Pro Arg Gly Pro Pro Gly Glu Pro Gly Pro Pro 
    50                  55                  60                  


Gly Pro Met Gly Pro Pro Gly Glu Lys Gly Glu Pro Gly Arg Gln Gly 
65                  70                  75                  80  


Leu Pro Gly Pro Pro Gly Ala Pro Gly Leu Asn Ala Ala Gly Ala Ile 
                85                  90                  95      


Ser Ala Ala Thr Tyr Ser Thr Val Pro Lys Ile Ala Phe Tyr Ala Gly 
            100                 105                 110         


Leu Lys Arg Gln His Glu Gly Tyr Glu Val Leu Lys Phe Asp Asp Val 
        115                 120                 125             


Val Thr Asn Leu Gly Asn His Tyr Asp Pro Thr Thr Gly Lys Phe Thr 
    130                 135                 140                 


Cys Ser Ile Pro Gly Ile Tyr Phe Phe Thr Tyr His Val Leu Met Arg 
145                 150                 155                 160 


Gly Gly Asp Gly Thr Ser Met Trp Ala Asp Leu Cys Lys Asn Asn Gln 
                165                 170                 175     


Val Arg Ala Ser Ala Ile Ala Gln Asp Ala Asp Gln Asn Tyr Asp Tyr 
            180                 185                 190         


Ala Ser Asn Ser Val Val Leu His Leu Glu Pro Gly Asp Glu Val Tyr 
        195                 200                 205             


Ile Lys Leu Asp Gly Gly Lys Ala His Gly Gly Asn Asn Asn Lys Tyr 
    210                 215                 220                 


Ser Thr Phe Ser Gly Phe Ile Ile Tyr Ala Asp 
225                 230                 235 


<210>  1430
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  1430

Gly Gly Val Gly Ala Arg Arg Glu Ala Gln Arg Thr Gln Gln Pro Gly 
1               5                   10                  15      


Gln Arg Ala Asp Pro Pro Asn Ala Thr Ala Ser Ala Ser Ser Arg Glu 
            20                  25                  30          


Gly Leu Pro Glu Ala Pro Lys Pro Ser Gln Ala Ser Gly Pro Glu Phe 
        35                  40                  45              


Ser Asp Ala His Met Thr Trp Leu Asn Phe Val Arg Arg Pro Asp Asp 
    50                  55                  60                  


Gly Ala Leu Arg Lys Arg Cys Gly Ser Arg Asp Lys Lys Pro Arg Asp 
65                  70                  75                  80  


Leu Phe Gly Pro Pro Gly Pro Pro Gly Ala Glu Val Thr Ala Glu Thr 
                85                  90                  95      


Leu Leu His Glu Phe Gln Glu Leu Leu Lys Glu Ala Thr Glu Arg Arg 
            100                 105                 110         


Phe Ser Gly Leu Leu Asp Pro Leu Leu Pro Gln Gly Ala Gly Leu Arg 
        115                 120                 125             


Leu Val Gly Glu Ala Phe His Cys Arg Leu Gln Gly Pro Arg Arg Val 
    130                 135                 140                 


Asp Lys Arg Thr Leu Val Glu Leu His Gly Phe Gln Ala Pro Ala Ala 
145                 150                 155                 160 


Gln Gly Ala Phe Leu Arg Gly Ser Gly Leu Ser Leu Ala Ser Gly Arg 
                165                 170                 175     


Phe Thr Ala Pro Val Ser Gly Ile Phe Gln Phe Ser Ala Ser Leu His 
            180                 185                 190         


Val Asp His Ser Glu Leu Gln Gly Lys Ala Arg Leu Arg Ala Arg Asp 
        195                 200                 205             


Val Val Cys Val Leu Ile Cys Ile Glu Ser Leu Cys Gln Arg His Thr 
    210                 215                 220                 


Cys Leu Glu Ala Val Ser Gly Leu Glu Ser Asn Ser Arg Val Phe Thr 
225                 230                 235                 240 


Leu Gln Val Gln Gly Leu Leu Gln Leu Gln Ala Gly Gln Tyr Ala Ser 
                245                 250                 255     


Val Phe Val Asp Asn Gly Ser Gly Ala Val Leu Thr Ile Gln Ala Gly 
            260                 265                 270         


Ser Ser Phe Ser Gly Leu Leu Leu Gly Thr 
        275                 280         


<210>  1431
<211>  200
<212>  PRT
<213>  Homo Sapiens

<400>  1431

Leu Asn Cys Phe Thr Lys Gly Gln Lys Asn Ser Thr Leu Ile Phe Thr 
1               5                   10                  15      


Arg Glu Asn Thr Ile Arg Asn Cys Ser Cys Ser Ala Asp Ile Arg Asp 
            20                  25                  30          


Cys Asp Tyr Ser Leu Ala Asn Leu Met Cys Asn Cys Lys Thr Val Leu 
        35                  40                  45              


Pro Leu Ala Val Glu Arg Thr Ser Tyr Asn Gly His Leu Thr Ile Trp 
    50                  55                  60                  


Phe Thr Asp Thr Ser Ala Leu Gly His Leu Leu Asn Phe Thr Leu Val 
65                  70                  75                  80  


Gln Asp Leu Lys Leu Ser Leu Cys Ser Thr Asn Thr Leu Pro Thr Glu 
                85                  90                  95      


Tyr Leu Ala Ile Cys Gly Leu Lys Arg Leu Arg Ile Asn Met Glu Ala 
            100                 105                 110         


Lys His Pro Phe Pro Glu Gln Ser Leu Leu Ile His Ser Gly Gly Asp 
        115                 120                 125             


Ser Asp Ser Arg Glu Lys Pro Met Trp Leu His Lys Gly Trp Gln Pro 
    130                 135                 140                 


Cys Met Tyr Ile Ser Phe Leu Asp Met Ala Leu Phe Asn Arg Asp Ser 
145                 150                 155                 160 


Ala Phe Lys Ser Tyr Ser Ile Glu Asn Val Thr Ser Ile Ala Asn Asn 
                165                 170                 175     


Phe Pro Asp Phe Ser Tyr Phe Arg Thr Phe Pro Met Pro Ser Asn Lys 
            180                 185                 190         


Ser Tyr Val Val Thr Phe Ile Tyr 
        195                 200 


<210>  1432
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  1432

Pro Glu Trp Glu Pro Val Gln Gly Leu Leu Ser Gln Asn His Ser Cys 
1               5                   10                  15      


Arg Asp Pro Gln Cys Cys Gly Asn Leu Leu Val Leu Cys Leu Phe Leu 
            20                  25                  30          


Val Trp Gln Val Arg His Cys Trp His Gln Val Thr Arg Thr Arg Phe 
        35                  40                  45              


Ser Thr Arg Asn Val Ile Lys Val Pro Leu Gln Lys Arg Ala Val Pro 
    50                  55                  60                  


Ser Met Arg Cys Glu Thr Val Phe Lys Leu Thr Pro Glu Phe Phe Ser 
65                  70                  75                  80  


Pro Gly Lys Ser Arg Gly Leu Asp Ser Gln Gln Cys Ala Gln Arg Gln 
                85                  90                  95      


Arg Trp Gly Tyr Arg Arg Ser Leu Gln Glu Ser Trp Ala Gln Asn Leu 
            100                 105                 110         


Leu Ser Pro Gln His Pro Cys Pro Gly Pro Pro Ser Gly Val His Thr 
        115                 120                 125             


His Ser Glu Pro Ile Phe Cys Thr Thr Ser Ile Ser Asn Thr Cys Leu 
    130                 135                 140                 


Leu Pro Gln Asn Ser Ser Trp Lys Ala Trp Gln Val Pro Trp Cys Leu 
145                 150                 155                 160 


His Asp Gly Gln Thr Arg Pro Ala Leu Asp Met Cys Gln Glu Met Glu 
                165                 170                 175     


Gln Leu Leu Leu His Ser Gln Glu Arg Leu Val Ser Leu Glu Pro Val 
            180                 185                 190         


Ile Ser Val Arg Ser Arg Pro Thr Ser Met Thr Leu Thr Thr Ser Leu 
        195                 200                 205             


Pro Asn Leu Leu Ser Ala Glu Arg Leu Gln Phe Cys Pro Gln Arg Ala 
    210                 215                 220                 


Pro Ala 
225     


<210>  1433
<211>  361
<212>  PRT
<213>  Homo Sapiens

<400>  1433

Ser Ser Cys Ser Gln Ala Arg Thr Met Asn Pro Gly Gly Ser Gly Gly 
1               5                   10                  15      


Ala Arg Cys Ser Leu Ser Ala Glu Val Arg Arg Arg Gln Cys Leu Gln 
            20                  25                  30          


Leu Ser Thr Val Pro Gly Ala Asp Pro Gln Arg Ser Asn Glu Leu Leu 
        35                  40                  45              


Leu Leu Ala Ala Ala Gly Glu Gly Leu Glu Arg Gln Asp Leu Pro Gly 
    50                  55                  60                  


Asp Pro Ala Lys Glu Glu Pro Gln Pro Pro Pro Gln His His Val Leu 
65                  70                  75                  80  


Tyr Phe Pro Gly Asp Val Gln Asn Tyr His Glu Ile Met Thr Arg His 
                85                  90                  95      


Pro Glu Asn Tyr Gln Trp Glu Asn Trp Ser Leu Glu Asn Val Ala Thr 
            100                 105                 110         


Ile Leu Ala His Arg Phe Pro Asn Ser Tyr Ile Trp Val Ile Lys Cys 
        115                 120                 125             


Ser Arg Met His Leu His Lys Phe Ser Cys Tyr Asp Asn Phe Val Lys 
    130                 135                 140                 


Ser Asn Met Phe Gly Ala Pro Glu His Asn Thr Asp Phe Gly Ala Phe 
145                 150                 155                 160 


Lys His Leu Tyr Met Leu Leu Val Asn Ala Phe Asn Leu Ser Gln Asn 
                165                 170                 175     


Ser Leu Ser Lys Lys Ser Leu Asn Val Trp Asn Lys Asp Ser Ile Ala 
            180                 185                 190         


Ser Asn Cys Arg Ser Ser Pro Ser His Thr Thr Asn Gly Cys Gln Gly 
        195                 200                 205             


Glu Lys Val Arg Thr Cys Glu Lys Ser Asp Glu Ser Ala Met Ser Phe 
    210                 215                 220                 


Tyr Pro Pro Ser Leu Asn Asp Ala Ser Phe Thr Leu Ile Gly Phe Ser 
225                 230                 235                 240 


Lys Gly Cys Val Val Leu Asn Gln Leu Leu Phe Glu Leu Lys Glu Ala 
                245                 250                 255     


Lys Lys Asp Lys Asn Ile Asp Ala Phe Ile Lys Ser Ile Arg Thr Met 
            260                 265                 270         


Tyr Trp Leu Asp Gly Gly His Ser Gly Gly Ser Asn Thr Trp Val Thr 
        275                 280                 285             


Tyr Pro Glu Val Leu Lys Glu Phe Ala Gln Thr Gly Ile Ile Val His 
    290                 295                 300                 


Thr His Val Thr Pro Tyr Gln Val Arg Asp Pro Met Arg Ser Trp Ile 
305                 310                 315                 320 


Gly Lys Glu His Lys Lys Phe Val Gln Ile Leu Gly Asp Leu Gly Met 
                325                 330                 335     


Gln Val Thr Ser Gln Ile His Phe Thr Lys Glu Ala Pro Ser Ile Glu 
            340                 345                 350         


Asn His Phe Arg Val His Glu Val Phe 
        355                 360     


<210>  1434
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  1434

Asp Glu Glu Glu Val Pro Glu Glu Trp Val Leu Leu His Val Val Gln 
1               5                   10                  15      


Gly Gln Ile Gly Ala Gly Asn Tyr Ser Tyr Leu Arg Leu Asn His Glu 
            20                  25                  30          


Gly Lys Ile Val Leu Arg Met Arg Ser Leu Lys Gly Asp Ala Asp Leu 
        35                  40                  45              


Tyr Val Ser Ala Ser Ser Leu His Pro Ser Phe Asp Asp Tyr Glu Leu 
    50                  55                  60                  


Gln Ser Ala Thr Cys Gly Pro Asp Ala Val Ser Ile Pro Ala His Phe 
65                  70                  75                  80  


Arg Arg Pro Val Gly Ile Gly Val Tyr Gly His Pro Ser His Leu Glu 
                85                  90                  95      


Ser Glu Phe Glu Met Lys Val Tyr Tyr Asp Gly Thr Val Glu Gln His 
            100                 105                 110         


Pro Phe Gly Glu Ala Ala Tyr Pro Ala Asp Gly Ala Asp Ala Gly Gln 
        115                 120                 125             


Lys His Ala Gly Ala Pro Glu Asp 
    130                 135     


<210>  1435
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  1435

Met Asp Ser Leu Asp Arg Ser Cys Gln Asp Trp Cys Asp Arg Lys Gln 
1               5                   10                  15      


His Trp Leu Glu Ile Gly Pro Pro Asp Leu Val Glu Arg Lys Gly Ser 
            20                  25                  30          


Leu Thr Leu Arg Ser His His Lys Lys Tyr Ser Lys Pro Val Leu Val 
        35                  40                  45              


Tyr Ser Trp His Arg Asp Arg Glu Ala Phe Pro Lys Gly Tyr Asp Ile 
    50                  55                  60                  


Glu Gly Pro Glu Lys Val Lys Lys Leu Cys Asn Ser Thr Tyr Arg Arg 
65                  70                  75                  80  


Leu Gly Thr Asp Glu Ser Pro Ile Trp Thr Ser Glu Thr His Glu Lys 
                85                  90                  95      


Leu Ser Gln Met Cys Leu Asn Thr Glu Trp Val Glu Met Lys Ser Lys 
            100                 105                 110         


Ala Leu Leu Asn Glu Glu Thr Val Ser Ser Gly 
        115                 120             


<210>  1436
<211>  182
<212>  PRT
<213>  Homo Sapiens

<400>  1436

Asn Lys Pro Ser Leu Ser Gly Arg Gln Ala Pro Ala Gln Ala Gln Thr 
1               5                   10                  15      


Ser Asp Leu Val Pro Ser Leu Phe Pro Leu Gly Leu Trp Ala Pro Gly 
            20                  25                  30          


Phe Cys Thr Trp Ser Ser Pro Asp Glu Asp Lys Val Trp Arg Pro Ala 
        35                  40                  45              


Trp Glu Gln Gly Pro Lys Gly Glu Pro Asp Pro Arg Gly Leu Arg Pro 
    50                  55                  60                  


Arg Lys Pro Val Pro Gly Thr Gly Asn Arg Asp Ser Gly Thr Arg Arg 
65                  70                  75                  80  


Arg Leu Gln Asp Ala Thr Glu Gln Asp Pro Arg Pro Gly Asn Asp Val 
                85                  90                  95      


Ala Ser Ala Glu Thr Ala Gly Pro Pro Ser Pro Ser Gly Ile Arg Ala 
            100                 105                 110         


Gln Asp Arg Ala Pro Arg His Arg Arg Ala Pro Pro Ala Arg Met Pro 
        115                 120                 125             


Val Ala Pro Ala Pro Ser Ala Asp Gly Glu Pro Leu Gln Glu Gln Gly 
    130                 135                 140                 


Gly Gly Leu Phe His Arg Thr Arg Ser Val Tyr Asn Gly Leu Glu Leu 
145                 150                 155                 160 


Asn Thr Trp Met Lys Val Glu Arg Leu Phe Val Glu Lys Phe His Gln 
                165                 170                 175     


Ser Phe Ser Leu Asp Asn 
            180         


<210>  1437
<211>  291
<212>  PRT
<213>  Homo Sapiens

<400>  1437

Gln His Val Ser Asp Trp Thr Tyr Ser Glu Gly Ala Leu Asp Glu Ala 
1               5                   10                  15      


His Trp Pro Gln His Tyr Pro Ala Cys Gly Gly Gln Arg Gln Ser Pro 
            20                  25                  30          


Ile Asn Leu Gln Arg Thr Lys Val Arg Tyr Asn Pro Ser Leu Lys Gly 
        35                  40                  45              


Leu Asn Met Thr Gly Tyr Glu Thr Gln Ala Gly Glu Phe Pro Met Val 
    50                  55                  60                  


Asn Asn Gly His Thr Val Gln Ile Ser Leu Pro Ser Thr Met Arg Met 
65                  70                  75                  80  


Thr Val Ala Asp Gly Thr Val Tyr Ile Ala Gln Gln Met His Phe His 
                85                  90                  95      


Trp Gly Gly Ala Ser Ser Glu Ile Ser Gly Ser Glu His Thr Val Asp 
            100                 105                 110         


Gly Ile Arg His Val Ile Glu Ile His Ile Val His Tyr Asn Ser Lys 
        115                 120                 125             


Tyr Lys Ser Tyr Asp Ile Ala Gln Asp Ala Pro Asp Gly Leu Ala Val 
    130                 135                 140                 


Leu Ala Ala Phe Val Glu Val Lys Asn Tyr Pro Glu Asn Thr Tyr Tyr 
145                 150                 155                 160 


Ser Asn Phe Ile Ser His Leu Ala Asn Ile Lys Tyr Pro Gly Gln Arg 
                165                 170                 175     


Thr Thr Leu Thr Gly Leu Asp Val Gln Asp Met Leu Pro Arg Asn Leu 
            180                 185                 190         


Gln His Tyr Tyr Thr Tyr His Gly Ser Leu Thr Thr Pro Pro Cys Thr 
        195                 200                 205             


Glu Asn Val His Trp Phe Val Leu Ala Asp Phe Val Lys Leu Ser Arg 
    210                 215                 220                 


Thr Gln Val Trp Lys Leu Glu Asn Ser Leu Leu Asp His Arg Asn Lys 
225                 230                 235                 240 


Thr Ile His Asn Asp Tyr Arg Arg Thr Gln Pro Leu Asn His Arg Val 
                245                 250                 255     


Val Glu Ser Asn Phe Pro Asn Gln Glu Tyr Thr Leu Gly Ser Glu Phe 
            260                 265                 270         


Gln Phe Tyr Leu His Lys Ile Glu Glu Ile Leu Asp Tyr Leu Arg Arg 
        275                 280                 285             


Ala Leu Asn 
    290     


<210>  1438
<211>  87
<212>  PRT
<213>  Homo Sapiens

<400>  1438

Met Val Lys Leu Gly Cys Ser Phe Ser Gly Lys Pro Gly Lys Asp Pro 
1               5                   10                  15      


Gly Asp Gln Asp Gly Ala Ala Met Asp Ser Val Pro Leu Ile Ser Pro 
            20                  25                  30          


Leu Asp Ile Ser Gln Leu Gln Pro Pro Leu Pro Asp Gln Val Val Ile 
        35                  40                  45              


Lys Thr Gln Thr Glu Tyr Gln Leu Ser Ser Pro Asp Gln Gln Asn Phe 
    50                  55                  60                  


Pro Asp Leu Glu Gly Gln Arg Leu Asn Cys Ser His Pro Glu Glu Gly 
65                  70                  75                  80  


Arg Arg Leu Pro Thr Ala Arg 
                85          


<210>  1439
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  1439

Gln Asn Asp Thr Glu Pro Ile Val Leu Glu Gly Lys Cys Leu Val Val 
1               5                   10                  15      


Cys Asp Ser Ser Pro Ser Ala Asp Gly Ala Val Thr Ser Ser Leu Gly 
            20                  25                  30          


Ile Ser Val Arg Ser Gly Ser Ala Lys Val Ala Phe Ser Ala Thr Arg 
        35                  40                  45              


Ser Thr Asn His Glu Pro Ser Glu Met Ser Asn Arg Thr Met Thr Ile 
    50                  55                  60                  


Tyr Phe Asp Gln Val Leu Val Asn Ile Gly Asn His Phe Asp Leu Ala 
65                  70                  75                  80  


Ser Ser Ile Phe Val Ala Pro Arg Lys Gly Ile Tyr Ser Phe Ser Phe 
                85                  90                  95      


His Val Val Lys Val Tyr Asn Arg Gln Thr Ile Gln Val Ser Leu Met 
            100                 105                 110         


Gln Asn Gly Tyr Pro Val Ile Ser Ala Phe Ala Gly Asp Gln Asp Val 
        115                 120                 125             


Thr Arg Glu Ala Ala Ser Asn Gly Val Leu Leu Leu Met Glu Arg Glu 
    130                 135                 140                 


Asp Lys Val His Leu Lys Leu Glu Arg Gly Asn Leu Met Gly Gly Trp 
145                 150                 155                 160 


Lys Tyr Ser Thr Phe Ser Gly Phe Leu Val Phe Pro Leu 
                165                 170             


<210>  1440
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  1440

Gln Glu Gly Ser Glu Pro Val Leu Leu Glu Gly Glu Cys Leu Val Val 
1               5                   10                  15      


Cys Glu Pro Gly Arg Ala Ala Ala Gly Gly Pro Gly Gly Ala Ala Leu 
            20                  25                  30          


Gly Glu Ala Pro Pro Gly Arg Val Ala Phe Ala Ala Val Arg Ser His 
        35                  40                  45              


His His Glu Pro Ala Gly Glu Thr Gly Asn Gly Thr Ser Gly Ala Ile 
    50                  55                  60                  


Tyr Phe Asp Gln Val Leu Val Asn Glu Gly Gly Gly Phe Asp Arg Ala 
65                  70                  75                  80  


Ser Gly Ser Phe Val Ala Pro Val Arg Gly Val Tyr Ser Phe Arg Phe 
                85                  90                  95      


His Val Val Lys Val Tyr Asn Arg Gln Thr Val Gln Val Ser Leu Met 
            100                 105                 110         


Leu Asn Thr Trp Pro Val Ile Ser Ala Phe Ala Asn Asp Pro Asp Val 
        115                 120                 125             


Thr Arg Glu Ala Ala Thr Ser Ser Val Leu Leu Pro Leu Asp Pro Gly 
    130                 135                 140                 


Asp Arg Val Ser Leu Arg Leu Arg Arg Gly Asn Leu Leu Gly Gly Trp 
145                 150                 155                 160 


Lys Tyr Ser Ser Phe Ser Gly Phe Leu Ile Phe Pro Leu 
                165                 170             


<210>  1441
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  1441

Ala Gln Pro Glu Asp Arg Arg Val Leu Arg Tyr Pro Gly Thr Ala Val 
1               5                   10                  15      


Met Val Thr Cys Pro Asn Arg Pro Leu Val Pro Arg Pro Leu Leu Thr 
            20                  25                  30          


Pro Gly Gly Ser Arg Ala Ser Leu Ala Leu Cys Ala Phe Val Ala Val 
        35                  40                  45              


Pro Gln Arg Ile Pro Gln Pro Leu Leu Pro Ala Tyr Ile Leu Leu Met 
    50                  55                  60                  


Leu Pro Ser Leu Val Val Asp Met Ala Leu Pro Ser Ser Arg Leu Leu 
65                  70                  75                  80  


Arg Ser Ile Lys Pro Ile Gln Pro Ala Ser Gln Val Val Arg Lys Glu 
                85                  90                  95      


Arg Asn Pro Asn Pro Asn Cys Pro Gln Ser Asp Pro Leu Met Lys Ala 
            100                 105                 110         


Ser Ser Thr Ser Phe Leu Ser His Thr Tyr Leu Ile Asn Lys Thr Arg 
        115                 120                 125             


Ser Thr Thr Arg Lys Val Glu Glu His Ser Trp Phe Thr Cys Thr Gly 
    130                 135                 140                 


Ala Lys Tyr Phe Ala Ile Pro Leu Ala Glu Arg Asn Thr Lys Arg Leu 
145                 150                 155                 160 


Thr Lys Arg Ser Thr His Ala Gln Leu Leu Arg Gly Lys Gln Asp Gly 
                165                 170                 175     


Ser Glu Trp Val Val Pro Arg Ser Ser Ala Ser Ser Asn Val Leu Tyr 
            180                 185                 190         


His 
    


<210>  1442
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  1442

Val Asn Gly Cys Cys Gly Leu Gln Met Ile Ala Leu Trp Ala Gln Ser 
1               5                   10                  15      


Ser Gly Asn Ala Asp Ala Arg Val Glu Glu Ile Leu Ala Gly Glu Glu 
            20                  25                  30          


Arg Arg Leu Ala Ala Leu Leu Gly Ser Gln Gly Met Arg Phe Trp Val 
        35                  40                  45              


Cys Leu Ala Ala Cys Arg Ala Met Trp Gly Leu Ala Ala Arg Arg Gly 
    50                  55                  60                  


Arg Ala Glu Asp Ser Ser Ser Ser Pro Val Asp Ala Ser Lys Phe Pro 
65                  70                  75                  80  


Trp Arg Gly Gly Gln His Arg Thr Thr Met Met Pro Cys Leu Leu Arg 
                85                  90                  95      


Val Gly Val Phe Arg Pro Cys His Val Arg Pro Thr Gly Asp Pro Ser 
            100                 105                 110         


Cys Asp Val Gln Pro Pro Arg Leu Gly Phe Ser Arg Val Pro Asp Thr 
        115                 120                 125             


Gln Val Ala Phe Tyr Gly Ser Gly His Trp Asp Pro Thr Pro Phe Ser 
    130                 135                 140                 


Val His Ser Cys Phe Phe Asn Phe Gln Val Arg Lys Ile Ile Phe Leu 
145                 150                 155                 160 


Leu 
    


<210>  1443
<211>  269
<212>  PRT
<213>  Homo Sapiens

<400>  1443

Gly His Leu Ser Ser Pro Pro Leu Val Asp Thr Leu His Gly Lys Val 
1               5                   10                  15      


Leu Gly Lys Phe Val Ser Leu Glu Gly Phe Ala Gln Pro Val Ala Val 
            20                  25                  30          


Phe Leu Gly Ile Pro Phe Ala Lys Pro Pro Leu Gly Pro Leu Arg Phe 
        35                  40                  45              


Thr Leu Pro Gln Pro Ala Glu Pro Trp Asn Phe Val Lys Asn Ala Thr 
    50                  55                  60                  


Ser Tyr Pro Pro Met Phe Thr Gln Asp Pro Lys Ala Gly Gln Leu Ile 
65                  70                  75                  80  


Ser Glu Leu Phe Thr Asn Arg Lys Glu Asn Ile Pro Leu Lys Leu Ser 
                85                  90                  95      


Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Thr Pro Ala Asp Leu Thr Lys 
            100                 105                 110         


Lys Asn Arg Leu Pro Val Met Val Trp Ile His Gly Gly Gly Leu Met 
        115                 120                 125             


Val Gly Ala Ala Ser Thr Tyr Asp Gly Leu Ala Leu Ala Ala His Glu 
    130                 135                 140                 


Asn Val Val Val Val Thr Ile Gln Tyr Arg Leu Gly Ile Trp Gly Phe 
145                 150                 155                 160 


Phe Ser Thr Gly Asp Glu His Ser Pro Gly Asn Trp Gly His Leu Asp 
                165                 170                 175     


Gln Leu Ala Ala Leu His Trp Val Gln Asp Asn Ile Ala Ser Phe Gly 
            180                 185                 190         


Gly Asn Pro Gly Ser Val Thr Ile Phe Gly Gly Ser Val Gly Gly Glu 
        195                 200                 205             


Ser Val Ser Val Leu Val Leu Ser Pro Leu Ala Lys Asn Leu Phe His 
    210                 215                 220                 


Arg Ala Ile Ser Glu Ser Gly Val Ala Leu Thr Ser Val Leu Val Lys 
225                 230                 235                 240 


Lys Gly Asp Val Lys Pro Leu Ala Glu Val Gly Leu Arg Leu Val Arg 
                245                 250                 255     


Leu Arg Leu Asp Thr Pro Thr Ser Leu Ala Leu Cys Ser 
            260                 265                 


<210>  1444
<211>  541
<212>  PRT
<213>  Homo Sapiens

<400>  1444

Ala Leu His Thr Lys Arg Pro Gln Val Val Thr Lys Tyr Gly Thr Leu 
1               5                   10                  15      


Gln Gly Lys Gln Met His Val Gly Lys Thr Pro Ile Gln Val Phe Leu 
            20                  25                  30          


Gly Val Pro Phe Ser Arg Pro Pro Leu Gly Ile Leu Arg Phe Ala Pro 
        35                  40                  45              


Pro Glu Pro Pro Glu Pro Trp Lys Gly Ile Arg Asp Ala Thr Thr Tyr 
    50                  55                  60                  


Pro Pro Gly Cys Leu Gln Glu Ser Trp Gly Gln Leu Ala Ser Met Tyr 
65                  70                  75                  80  


Val Ser Thr Arg Glu Arg Tyr Lys Trp Leu Arg Phe Ser Glu Asp Cys 
                85                  90                  95      


Leu Tyr Leu Asn Val Tyr Ala Pro Ala Arg Ala Pro Gly Asp Pro Gln 
            100                 105                 110         


Leu Pro Val Met Val Trp Phe Pro Gly Gly Ala Phe Ile Val Gly Ala 
        115                 120                 125             


Ala Ser Ser Tyr Glu Gly Ser Asp Leu Ala Ala Arg Glu Lys Val Val 
    130                 135                 140                 


Leu Val Phe Leu Gln His Arg Leu Gly Ile Phe Gly Phe Leu Ser Thr 
145                 150                 155                 160 


Asp Asp Ser His Ala Arg Gly Asn Trp Gly Leu Leu Asp Gln Met Ala 
                165                 170                 175     


Ala Leu Arg Trp Val Gln Glu Asn Ile Ala Ala Phe Gly Gly Asp Pro 
            180                 185                 190         


Gly Asn Val Thr Leu Phe Gly Gln Ser Ala Gly Ala Met Ser Ile Ser 
        195                 200                 205             


Gly Leu Met Met Ser Pro Leu Ala Ser Gly Leu Phe His Arg Ala Ile 
    210                 215                 220                 


Ser Gln Ser Gly Thr Ala Leu Phe Arg Leu Phe Ile Thr Ser Asn Pro 
225                 230                 235                 240 


Leu Lys Val Ala Lys Lys Val Ala His Leu Ala Gly Cys Asn His Asn 
                245                 250                 255     


Ser Thr Gln Ile Leu Val Asn Cys Leu Arg Ala Leu Ser Gly Thr Lys 
            260                 265                 270         


Val Met Arg Val Ser Asn Lys Met Arg Phe Leu Gln Leu Asn Phe Gln 
        275                 280                 285             


Arg Asp Pro Glu Glu Ile Ile Trp Ser Met Ser Pro Val Val Asp Gly 
    290                 295                 300                 


Val Val Ile Pro Asp Asp Pro Leu Val Leu Leu Thr Gln Gly Lys Val 
305                 310                 315                 320 


Ser Ser Val Pro Tyr Leu Leu Gly Val Asn Asn Leu Glu Phe Asn Trp 
                325                 330                 335     


Leu Leu Pro Tyr Ile Met Lys Phe Pro Leu Asn Arg Gln Ala Met Arg 
            340                 345                 350         


Lys Glu Thr Ile Thr Lys Met Leu Trp Ser Thr Arg Thr Leu Leu Asn 
        355                 360                 365             


Ile Thr Lys Glu Gln Val Pro Leu Val Val Glu Glu Tyr Leu Asp Asn 
    370                 375                 380                 


Val Asn Glu His Asp Trp Lys Met Leu Arg Asn Arg Met Met Asp Ile 
385                 390                 395                 400 


Val Gln Asp Ala Thr Phe Val Tyr Ala Thr Leu Gln Thr Ala His Tyr 
                405                 410                 415     


His Arg Asp Ala Gly Leu Pro Val Tyr Leu Tyr Glu Phe Glu His His 
            420                 425                 430         


Ala Arg Gly Ile Ile Val Lys Pro Arg Thr Asp Gly Ala Asp His Gly 
        435                 440                 445             


Asp Glu Met Tyr Phe Leu Phe Gly Gly Pro Phe Ala Thr Gly Leu Ser 
    450                 455                 460                 


Met Gly Lys Glu Lys Ala Leu Ser Leu Gln Met Met Lys Tyr Trp Ala 
465                 470                 475                 480 


Asn Phe Ala Arg Thr Gly Asn Pro Asn Asp Gly Asn Leu Pro Cys Trp 
                485                 490                 495     


Pro Arg Tyr Asn Lys Asp Glu Lys Tyr Leu Gln Leu Asp Phe Thr Thr 
            500                 505                 510         


Arg Val Gly Met Lys Leu Lys Glu Lys Lys Met Ala Phe Trp Met Ser 
        515                 520                 525             


Leu Tyr Gln Ser Gln Arg Pro Glu Lys Gln Arg Gln Phe 
    530                 535                 540     


<210>  1445
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  1445

Ala Pro Thr Lys Gly Pro Ser Ala Glu Gly Pro Gln Arg Asn Thr Arg 
1               5                   10                  15      


Leu Gly Trp Ile Gln Gly Lys Gln Val Thr Val Leu Gly Ser Pro Val 
            20                  25                  30          


Pro Val Asn Val Phe Leu Gly Val Pro Phe Ala Ala Pro Pro Leu Gly 
        35                  40                  45              


Ser Leu Arg Phe Thr Asn Pro Gln Pro Ala Ser Pro Trp Asp Asn Leu 
    50                  55                  60                  


Arg Glu Ala Thr Ser Tyr Pro Asn Leu Cys Leu Gln Asn Ser Glu Trp 
65                  70                  75                  80  


Leu Leu Leu Asp Gln His Met Leu Lys Val His Tyr Pro Lys Phe Gly 
                85                  90                  95      


Val Ser Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Ala Pro Ala His Ala 
            100                 105                 110         


Asp Thr Gly Ser Lys Leu Pro Val Leu Val Trp Phe Pro Gly Gly Ala 
        115                 120                 125             


Phe Lys Thr Gly Ser Ala Ser Ile Phe Asp Gly Ser Ala Leu Ala Ala 
    130                 135                 140                 


Tyr Glu Asp Val Leu Val Val Val Val Gln Tyr Arg Leu Gly Ile Phe 
145                 150                 155                 160 


Gly Phe Phe Thr Thr Trp Asp Gln His Ala Pro Gly Asn Trp Ala Phe 
                165                 170                 175     


Lys Asp Gln Val Ala Ala Leu Ser Trp Val Gln Lys Asn Ile Glu Phe 
            180                 185                 190         


Phe Gly Gly Asp Pro Ser Ser Val Thr Ile Phe Gly Glu Ser Ala Gly 
        195                 200                 205             


Ala Ile Ser Val Ser Ser Leu Ile Leu Ser Pro Met Ala Lys Gly Leu 
    210                 215                 220                 


Phe His Lys Ala Ile Met Glu Ser Gly Val Ala Ile Ile Pro Tyr Leu 
225                 230                 235                 240 


Glu Ala His Asp Tyr Glu Lys Ser Glu Asp Leu Gln Val Val Ala His 
                245                 250                 255     


Phe Cys Gly Asn Asn Ala Ser Asp Ser Glu Ala Leu Leu Arg Cys Leu 
            260                 265                 270         


Arg Thr Lys Pro Ser Lys Glu Leu Leu Thr Leu Ser Gln Lys Thr Lys 
        275                 280                 285             


Ser Phe Thr Arg Val Val Asp Gly Ala Phe Phe Pro Asn Glu Pro Leu 
    290                 295                 300                 


Asp Leu Leu Ser Gln Lys Ala Phe Lys Ala Ile Pro Ser Ile Ile Gly 
305                 310                 315                 320 


Val Asn Asn His Glu Cys Gly Phe Leu Leu Pro Met Lys Glu Ala Pro 
                325                 330                 335     


Glu Ile Leu Ser Gly Ser Asn Lys Ser Leu Ala Leu His Leu Ile Gln 
            340                 345                 350         


Asn Ile Leu His Ile Pro Pro Gln Tyr Leu His Leu Val Ala Asn Glu 
        355                 360                 365             


Tyr Phe His Asp Lys His Ser Leu Thr Glu Ile Arg Asp Ser Leu Leu 
    370                 375                 380                 


Asp Leu Leu Gly Asp Val Phe Phe Val Val Pro Ala Leu Ile Thr Ala 
385                 390                 395                 400 


Arg Tyr His Arg Asp Ala Gly Ala Pro Val Tyr Phe Tyr Glu Phe Arg 
                405                 410                 415     


His Arg Pro Gln Cys Phe Glu Asp Thr Lys Pro Ala Phe Val Lys Ala 
            420                 425                 430         


Asp His Ala Asp Glu Val Arg Phe Val Phe Gly Gly Ala Phe Leu Lys 
        435                 440                 445             


Gly Asp Ile Val Met Phe Glu Gly Ala Thr Glu Glu Glu Lys Leu Leu 
    450                 455                 460                 


Ser Arg Lys Met Met Lys Tyr Trp Ala Thr Phe Ala Arg Thr Gly Asn 
465                 470                 475                 480 


Pro Asn Gly Asn Asp Leu Ser Leu Trp Pro Ala Tyr Asn Leu Thr Glu 
                485                 490                 495     


Gln Tyr Leu Gln Leu Asp Leu Asn Met Ser Leu Gly Gln Arg Leu Lys 
            500                 505                 510         


Glu Pro Arg Val Asp Phe Trp Thr Ser Thr Ile Pro Leu Ile Leu Ser 
        515                 520                 525             


Ala Ser Asp Met Leu His Ser Pro Leu Ser Ser Leu Thr Phe Leu Ser 
    530                 535                 540                 


Leu Leu Gln Pro Phe Phe Phe Phe Cys Ala Pro 
545                 550                 555 


<210>  1446
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  1446

Ala Pro Asp Val Gln Asp Cys Pro Glu Cys Thr Leu Gln Glu Asn Pro 
1               5                   10                  15      


Phe Phe Ser Gln Pro Gly Ala Pro Ile Leu Gln Cys Met Gly Cys Cys 
            20                  25                  30          


Phe Ser Arg Ala Tyr Pro Thr Pro Leu Arg Ser Lys Lys Thr Met Leu 
        35                  40                  45              


Val Gln Lys Asn Val Thr Ser Glu Ser Thr Cys Cys Val Ala Lys Ser 
    50                  55                  60                  


Tyr Asn Arg Val Thr Val Met Gly Gly Phe Lys Val Glu Asn His Thr 
65                  70                  75                  80  


Ala Cys His Cys Ser Thr Cys Tyr Tyr His Lys Ser 
                85                  90          


<210>  1447
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  1447

Ser Lys Glu Pro Leu Arg Pro Arg Cys Arg Pro Ile Asn Ala Thr Leu 
1               5                   10                  15      


Ala Val Glu Lys Glu Gly Cys Pro Val Cys Ile Thr Val Asn Thr Thr 
            20                  25                  30          


Ile Cys Ala Gly Tyr Cys Pro Thr Met Thr Arg Val Leu Gln Gly Val 
        35                  40                  45              


Leu Pro Ala Leu Pro Gln Val Val Cys Asn Tyr Arg Asp Val Arg Phe 
    50                  55                  60                  


Glu Ser Ile Arg Leu Pro Gly Cys Pro Arg Gly Val Asn Pro Val Val 
65                  70                  75                  80  


Ser Tyr Ala Val Ala Leu Ser Cys Gln Cys Ala Leu Cys Arg Arg Ser 
                85                  90                  95      


Thr Thr Asp Cys Gly Gly Pro Lys Asp His Pro Leu Thr Cys Asp Asp 
            100                 105                 110         


Pro Arg Phe Gln Asp Ser Ser Ser Ser Lys Ala Pro Pro Pro Ser Leu 
        115                 120                 125             


Pro Ser Pro Ser Arg Leu Pro Gly Pro 
    130                 135         


<210>  1448
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  1448

Ser Lys Glu Pro Leu Arg Pro Arg Cys Arg Pro Ile Asn Ala Thr Leu 
1               5                   10                  15      


Ala Val Glu Lys Glu Gly Cys Pro Val Cys Ile Thr Val Asn Thr Thr 
            20                  25                  30          


Ile Cys Ala Gly Tyr Cys Pro Thr Met Thr Arg Val Leu Gln Gly Val 
        35                  40                  45              


Leu Pro Ala Leu Pro Gln Val Val Cys Asn Tyr Arg Asp Val Arg Phe 
    50                  55                  60                  


Glu Ser Ile Arg Leu Pro Gly Cys Pro Arg Gly Val Asn Pro Val Val 
65                  70                  75                  80  


Ser Tyr Ala Val Ala Leu Ser Cys Gln Cys Ala Leu Cys Arg Arg Ser 
                85                  90                  95      


Thr Thr Asp Cys Gly Gly Pro Lys Asp His Pro Leu Thr Cys Asp Asp 
            100                 105                 110         


Pro Arg Phe Gln Ala Ser Ser Ser Ser Lys Ala Pro Pro Pro Ser Leu 
        115                 120                 125             


Pro Ser Pro Ser Arg Leu Pro Gly Pro Ser Asp Thr Pro Ile Leu Pro 
    130                 135                 140                 


Gln 
145 


<210>  1449
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  1449

Ser Lys Glu Pro Leu Arg Pro Arg Cys Arg Pro Ile Asn Ala Thr Leu 
1               5                   10                  15      


Ala Val Glu Lys Glu Gly Cys Pro Val Cys Ile Thr Val Asn Thr Thr 
            20                  25                  30          


Ile Cys Ala Gly Tyr Cys Pro Thr Met Thr Arg Val Leu Gln Gly Val 
        35                  40                  45              


Leu Pro Ala Leu Pro Gln Val Val Cys Asn Tyr Arg Asp Val Arg Phe 
    50                  55                  60                  


Glu Ser Ile Arg Leu Pro Gly Cys Pro Arg Gly Val Asn Pro Val Val 
65                  70                  75                  80  


Ser Tyr Ala Val Ala Leu Ser Cys Gln Cys Ala Leu Cys Arg Arg Ser 
                85                  90                  95      


Thr Thr Asp Cys Gly Gly Pro Lys Asp His Pro Leu Thr Cys Asp Asp 
            100                 105                 110         


Pro Arg Phe Gln Asp Ser Ser Ser Ser Lys Ala Pro Pro Pro Ser Leu 
        115                 120                 125             


Pro Ser Pro Ser Arg Leu Pro Gly Pro Ser Asp Thr Pro Ile Leu Pro 
    130                 135                 140                 


Gln 
145 


<210>  1450
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  1450

Ser Arg Glu Met Leu Arg Pro Arg Cys Arg Pro Ile Asn Ala Thr Leu 
1               5                   10                  15      


Ala Val Glu Lys Glu Gly Cys Pro Val Cys Ile Thr Val Asn Thr Thr 
            20                  25                  30          


Ile Cys Ala Gly Tyr Cys Pro Thr Met Thr Arg Val Leu Gln Gly Val 
        35                  40                  45              


Leu Pro Ala Leu Pro Gln Val Val Cys Asn Tyr Arg Asp Val Arg Phe 
    50                  55                  60                  


Glu Ser Ile Arg Leu Pro Gly Cys Pro Arg Gly Val Asn Pro Val Val 
65                  70                  75                  80  


Ser Tyr Ala Val Ala Leu Ser Cys Gln Cys Ala Leu Cys Arg Arg Ser 
                85                  90                  95      


Thr Thr Asp Cys Gly Gly Pro Lys Asp His Pro Leu Thr Cys Asp Asp 
            100                 105                 110         


Pro Arg Phe Gln Ala Ser Ser Ser Ser Lys Ala Pro Pro Pro Ser Leu 
        115                 120                 125             


Pro Ser Pro Ser Arg Leu Pro Gly Pro Ser Asp Thr Pro Ile Leu Pro 
    130                 135                 140                 


Gln 
145 


<210>  1451
<211>  455
<212>  PRT
<213>  Homo Sapiens

<400>  1451

Tyr Gln Leu Thr Cys Tyr Phe Thr Asn Trp Ala Gln Tyr Arg Pro Gly 
1               5                   10                  15      


Leu Gly Arg Phe Met Pro Asp Asn Ile Asp Pro Cys Leu Cys Thr His 
            20                  25                  30          


Leu Ile Tyr Ala Phe Ala Gly Arg Gln Asn Asn Glu Ile Thr Thr Ile 
        35                  40                  45              


Glu Trp Asn Asp Val Thr Leu Tyr Gln Ala Phe Asn Gly Leu Lys Asn 
    50                  55                  60                  


Lys Asn Ser Gln Leu Lys Thr Leu Leu Ala Ile Gly Gly Trp Asn Phe 
65                  70                  75                  80  


Gly Thr Ala Pro Phe Thr Ala Met Val Ser Thr Pro Glu Asn Arg Gln 
                85                  90                  95      


Thr Phe Ile Thr Ser Val Ile Lys Phe Leu Arg Gln Tyr Glu Phe Asp 
            100                 105                 110         


Gly Leu Asp Phe Asp Trp Glu Tyr Pro Gly Ser Arg Gly Ser Pro Pro 
        115                 120                 125             


Gln Asp Lys His Leu Phe Thr Val Leu Val Gln Glu Met Arg Glu Ala 
    130                 135                 140                 


Phe Glu Gln Glu Ala Lys Gln Ile Asn Lys Pro Arg Leu Met Val Thr 
145                 150                 155                 160 


Ala Ala Val Ala Ala Gly Ile Ser Asn Ile Gln Ser Gly Tyr Glu Ile 
                165                 170                 175     


Pro Gln Leu Ser Gln Tyr Leu Asp Tyr Ile His Val Met Thr Tyr Asp 
            180                 185                 190         


Leu His Gly Ser Trp Glu Gly Tyr Thr Gly Glu Asn Ser Pro Leu Tyr 
        195                 200                 205             


Lys Tyr Pro Thr Asp Thr Gly Ser Asn Ala Tyr Leu Asn Val Asp Tyr 
    210                 215                 220                 


Val Met Asn Tyr Trp Lys Asp Asn Gly Ala Pro Ala Glu Lys Leu Ile 
225                 230                 235                 240 


Val Gly Phe Pro Thr Tyr Gly His Asn Phe Ile Leu Ser Asn Pro Ser 
                245                 250                 255     


Asn Thr Gly Ile Gly Ala Pro Thr Ser Gly Ala Gly Pro Ala Gly Pro 
            260                 265                 270         


Tyr Ala Lys Glu Ser Gly Ile Trp Ala Tyr Tyr Glu Ile Cys Thr Phe 
        275                 280                 285             


Leu Lys Asn Gly Ala Thr Gln Gly Trp Asp Ala Pro Gln Glu Val Pro 
    290                 295                 300                 


Tyr Ala Tyr Gln Gly Asn Val Trp Val Gly Tyr Asp Asn Ile Lys Ser 
305                 310                 315                 320 


Phe Asp Ile Lys Ala Gln Trp Leu Lys His Asn Lys Phe Gly Gly Ala 
                325                 330                 335     


Met Val Trp Ala Ile Asp Leu Asp Asp Phe Thr Gly Thr Phe Cys Asn 
            340                 345                 350         


Gln Gly Lys Phe Pro Leu Ile Ser Thr Leu Lys Lys Ala Leu Gly Leu 
        355                 360                 365             


Gln Ser Ala Ser Cys Thr Ala Pro Ala Gln Pro Ile Glu Pro Ile Thr 
    370                 375                 380                 


Ala Ala Pro Ser Gly Ser Gly Asn Gly Ser Gly Ser Ser Ser Ser Gly 
385                 390                 395                 400 


Gly Ser Ser Gly Gly Ser Gly Phe Cys Ala Val Arg Ala Asn Gly Leu 
                405                 410                 415     


Tyr Pro Val Ala Asn Asn Arg Asn Ala Phe Trp His Cys Val Asn Gly 
            420                 425                 430         


Val Thr Tyr Gln Gln Asn Cys Gln Ala Gly Leu Val Phe Asp Thr Ser 
        435                 440                 445             


Cys Asp Cys Cys Asn Trp Ala 
    450                 455 


<210>  1452
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1452

Ser Glu His Glu Thr Arg Leu Val Ala Lys Leu Phe Lys Asp Tyr Ser 
1               5                   10                  15      


Ser Val Val Arg Pro Val Glu Asp His Arg Gln Val Val Glu Val Thr 
            20                  25                  30          


Val Gly Leu Gln Leu Ile Gln Leu Ile Asn Val Asp Glu Val Asn Gln 
        35                  40                  45              


Ile Val Thr Thr Asn Val Arg Leu Lys Gln Gly Asp Met Val Asp Leu 
    50                  55                  60                  


Pro Arg Pro Ser Cys Val Thr Leu Gly Val Pro Leu Phe Ser His Leu 
65                  70                  75                  80  


Gln Asn Glu Gln Trp Val Asp Tyr Asn Leu Lys Trp Asn Pro Asp Asp 
                85                  90                  95      


Tyr Gly Gly Val Lys Lys Ile His Ile Pro Ser Glu Lys Ile Trp Arg 
            100                 105                 110         


Pro Asp Leu Val Leu Tyr Asn Asn Ala Asp Gly Asp Phe Ala Ile Val 
        115                 120                 125             


Lys Phe Thr Lys Val Leu Leu Gln Tyr Thr Gly His Ile Thr Trp Thr 
    130                 135                 140                 


Pro Pro Ala Ile Phe Lys Ser Tyr Cys Glu Ile Ile Val Thr His Phe 
145                 150                 155                 160 


Pro Phe Asp Glu Gln Asn Cys Ser Met Lys Leu Gly Thr Trp Thr Tyr 
                165                 170                 175     


Asp Gly Ser Val Val Ala Ile Asn Pro Glu Ser Asp Gln Pro Asp Leu 
            180                 185                 190         


Ser Asn Phe Met Glu Ser Gly Glu Trp Val Ile Lys Glu Ser Arg Gly 
        195                 200                 205             


Trp Lys His Ser Val Thr Tyr Ser Cys Cys Pro Asp Thr Pro Tyr Leu 
    210                 215                 220                 


Asp Ile Thr Tyr His Phe Val Met Gln Arg Leu 
225                 230                 235 


<210>  1453
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  1453

Glu Glu Ala Lys Arg Pro Pro Pro Arg Ala Pro Gly Asp Pro Leu Ser 
1               5                   10                  15      


Ser Pro Ser Pro Thr Ala Leu Pro Gln Gly Gly Ser His Thr Glu Thr 
            20                  25                  30          


Glu Asp Arg Leu Phe Lys His Leu Phe Arg Gly Tyr Asn Arg Trp Ala 
        35                  40                  45              


Arg Pro Val Pro Asn Thr Ser Asp Val Val Ile Val Arg Phe Gly Leu 
    50                  55                  60                  


Ser Ile Ala Gln Leu Ile Asp Val Asp Glu Lys Asn Gln Met Met Thr 
65                  70                  75                  80  


Thr Asn Val Trp Leu Lys Gln Glu Trp Ser Asp Tyr Lys Leu Arg Trp 
                85                  90                  95      


Asn Pro Thr Asp Phe Gly Asn Ile Thr Ser Leu Arg Val Pro Ser Glu 
            100                 105                 110         


Met Ile Trp Ile Pro Asp Ile Val Leu Tyr Asn Asn Ala Asp Gly Glu 
        115                 120                 125             


Phe Ala Val Thr His Met Thr Lys Ala His Leu Phe Ser Thr Gly Thr 
    130                 135                 140                 


Val His Trp Val Pro Pro Ala Ile Tyr Lys Ser Ser Cys Ser Ile Asp 
145                 150                 155                 160 


Val Thr Phe Phe Pro Phe Asp Gln Gln Asn Cys Lys Met Lys Phe Gly 
                165                 170                 175     


Ser Trp Thr Tyr Asp Lys Ala Lys Ile Asp Leu Glu Gln Met Glu Gln 
            180                 185                 190         


Thr Val Asp Leu Lys Asp Tyr Trp Glu Ser Gly Glu Trp Ala Ile Val 
        195                 200                 205             


Asn Ala Thr Gly Thr Tyr Asn Ser Lys Lys Tyr Asp Cys Cys Ala Glu 
    210                 215                 220                 


Ile Tyr Pro Asp Val Thr Tyr Ala Phe Val Ile Arg Arg Leu 
225                 230                 235             


<210>  1454
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  1454

Lys Asn Glu Glu Leu Arg Leu Tyr His His Leu Phe Asn Asn Tyr Asp 
1               5                   10                  15      


Pro Gly Ser Arg Pro Val Arg Glu Pro Glu Asp Thr Val Thr Ile Ser 
            20                  25                  30          


Leu Lys Val Thr Leu Thr Asn Leu Ile Ser Leu Asn Glu Lys Glu Glu 
        35                  40                  45              


Thr Leu Thr Thr Ser Val Trp Ile Gly Ile Asp Trp Gln Asp Tyr Arg 
    50                  55                  60                  


Leu Asn Tyr Ser Lys Asp Asp Phe Gly Gly Ile Glu Thr Leu Arg Val 
65                  70                  75                  80  


Pro Ser Glu Leu Val Trp Leu Pro Glu Ile Val Leu Glu Asn Asn Ile 
                85                  90                  95      


Asp Gly Gln Phe Gly Val Ala Tyr Asp Ala Asn Val Leu Val Tyr Glu 
            100                 105                 110         


Gly Gly Ser Val Thr Trp Leu Pro Pro Ala Ile Tyr Arg Ser Val Cys 
        115                 120                 125             


Ala Val Glu Val Thr Tyr Phe Pro Phe Asp Trp Gln Asn Cys Ser Leu 
    130                 135                 140                 


Ile Phe Arg Ser Gln Thr Tyr Asn Ala Glu Glu Val Glu Phe Thr Phe 
145                 150                 155                 160 


Ala Val Asp Asn Asp Gly Lys Thr Ile Asn Lys Ile Asp Ile Asp Thr 
                165                 170                 175     


Glu Ala Tyr Thr Glu Asn Gly Glu Trp Ala Ile Asp Phe Cys Pro Gly 
            180                 185                 190         


Val Ile Arg Arg His His Gly Gly Ala Thr Asp Gly Pro Gly Glu Thr 
        195                 200                 205             


Asp Val Ile Tyr Ser Leu Ile Ile Arg Arg Lys 
    210                 215                 


<210>  1455
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  1455

Arg Asn Gln Glu Glu Arg Leu Leu Ala Asp Leu Met Gln Asn Tyr Asp 
1               5                   10                  15      


Pro Asn Leu Arg Pro Ala Glu Arg Asp Ser Asp Val Val Asn Val Ser 
            20                  25                  30          


Leu Lys Leu Thr Leu Thr Asn Leu Ile Ser Leu Asn Glu Arg Glu Glu 
        35                  40                  45              


Ala Leu Thr Thr Asn Val Trp Ile Glu Met Gln Trp Cys Asp Tyr Arg 
    50                  55                  60                  


Leu Arg Trp Asp Pro Arg Asp Tyr Glu Gly Leu Trp Val Leu Arg Val 
65                  70                  75                  80  


Pro Ser Thr Met Val Trp Arg Pro Asp Ile Val Leu Glu Asn Asn Val 
                85                  90                  95      


Asp Gly Val Phe Glu Val Ala Leu Tyr Cys Asn Val Leu Val Ser Pro 
            100                 105                 110         


Asp Gly Cys Ile Tyr Trp Leu Pro Pro Ala Ile Phe Arg Ser Ala Cys 
        115                 120                 125             


Ser Ile Ser Val Thr Tyr Phe Pro Phe Asp Trp Gln Asn Cys Ser Leu 
    130                 135                 140                 


Ile Phe Gln Ser Gln Thr Tyr Ser Thr Asn Glu Ile Asp Leu Gln Leu 
145                 150                 155                 160 


Ser Gln Glu Asp Gly Gln Thr Ile Glu Trp Ile Phe Ile Asp Pro Glu 
                165                 170                 175     


Ala Phe Thr Glu Asn Gly Glu Trp Ala Ile Gln His Arg Pro Ala Lys 
            180                 185                 190         


Met Leu Leu Asp Pro Ala Ala Pro Ala Gln Glu Ala Gly His Gln Lys 
        195                 200                 205             


Val Val Phe Tyr Leu Leu Ile Gln Arg Lys 
    210                 215             


<210>  1456
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  1456

Ser Ser Leu Val Thr Leu Asn Asn Asn Gly Tyr Asp Gly Ile Val Ile 
1               5                   10                  15      


Ala Ile Asn Pro Ser Val Pro Glu Asp Glu Lys Leu Ile Gln Asn Ile 
            20                  25                  30          


Lys Glu Met Val Thr Glu Ala Ser Thr His Leu Phe His Ala Thr Lys 
        35                  40                  45              


Gln Arg Ala Tyr Phe Arg Asn Val Ser Ile Leu Ile Pro Met Thr Tyr 
    50                  55                  60                  


Lys Ser Lys Ser Glu Tyr Leu Ile Pro Lys Gln Glu Thr Tyr Asp Gln 
65                  70                  75                  80  


Ala Asp Val Ile Val Ala Asp Leu Tyr Leu Lys Tyr Gly Asp Asp Pro 
                85                  90                  95      


Tyr Thr Leu Gln Tyr Gly Gln Cys Gly Asp Lys Gly Gln Tyr Ile His 
            100                 105                 110         


Phe Thr Pro Asn Phe Leu Leu Thr Asn Asn Leu Ala Thr Tyr Gly Pro 
        115                 120                 125             


Arg Gly Lys Val Phe Val His Gly Trp Ala His Leu Arg Trp Gly Val 
    130                 135                 140                 


Phe Asp Glu Tyr Asn Val Asp Gln Pro Phe Tyr Ile Ser Arg Arg Asn 
145                 150                 155                 160 


Thr Thr Glu Ala Thr Arg Cys Ser Thr Arg Ile Thr Val Tyr Met Val 
                165                 170                 175     


Leu Asn Glu Cys Lys Gly Ala Ser Cys Ile Ala Arg Pro Phe Arg Arg 
            180                 185                 190         


Asp Ser Gln Thr Gly Leu Tyr Glu Ala Lys Cys Thr Phe Ile Pro Lys 
        195                 200                 205             


Arg Ser Gln Thr Ala Lys Glu Ser Ile Val Phe Met Gln Asn Leu Asp 
    210                 215                 220                 


Ser Val Thr Glu Phe Cys Thr Glu Lys Thr His Asn Lys Glu Ala Pro 
225                 230                 235                 240 


Asn Leu 
        


<210>  1457
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  1457

Trp Ser Lys His Ala Lys Pro Val Ala Cys Ser Gly Asp Trp Leu Gly 
1               5                   10                  15      


Val Arg Asp Lys Cys Phe Tyr Phe Ser Asp Asp Thr Arg Asn Trp Thr 
            20                  25                  30          


Ala Ser Lys Ile Phe Cys Ser Leu Gln Lys Ala Glu Leu Ala Gln Ile 
        35                  40                  45              


Asp Thr Gln Glu Asp Met Glu Phe Leu Lys Arg Tyr Ala Gly Thr Asp 
    50                  55                  60                  


Met His Trp Ile Gly Leu Ser Arg Lys Gln Gly Asp Ser Trp Lys Trp 
65                  70                  75                  80  


Thr Asn Gly Thr Thr Phe Asn Gly Trp Phe Glu Ile Ile Gly Asn Gly 
                85                  90                  95      


Ser Phe Ala Phe Leu Ser Ala Asp Gly Val His Ser Ser Arg Gly Phe 
            100                 105                 110         


Ile Asp Ile Lys Trp Ile Cys Ser Lys Pro Lys Tyr Phe Leu 
        115                 120                 125     


<210>  1458
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  1458

Ala Leu Pro Gln Tyr Lys Lys Lys Ile Thr Asp Arg Cys Phe His His 
1               5                   10                  15      


Ser Glu Cys Tyr Ser Gly Cys Cys Leu Met Asp Leu Asp Ser Gly Gly 
            20                  25                  30          


Ala Phe Cys Ala Pro Arg Ala Arg Ile Thr Met Ile Cys Leu Pro Gln 
        35                  40                  45              


Thr Lys Gly Ala Thr Asn Ile Ile Cys Pro Cys Arg Met Gly Leu Thr 
    50                  55                  60                  


Cys Ile Ser Lys Asp Leu Met Cys Ser Arg Arg Cys His Met Ile 
65                  70                  75                  


<210>  1459
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  1459

Glu Leu Cys Gln Pro Gly Ala Glu Asn Ala Phe Lys Val Arg Leu Ser 
1               5                   10                  15      


Ile Arg Thr Ala Leu Gly Asp Lys Ala Tyr Ala Trp Asp Thr Asn Glu 
            20                  25                  30          


Glu Tyr Leu Phe Lys Ala Met Val Ala Phe Ser Met Arg Lys Val Pro 
        35                  40                  45              


Asn Arg Glu Ala Thr Glu Ile Ser His Val Leu Leu Cys Asn Val Thr 
    50                  55                  60                  


Gln Arg Val Ser Phe Trp Phe Val Val Thr Asp Pro Ser Lys Asn His 
65                  70                  75                  80  


Thr Leu Pro Ala Val Glu Val Gln Ser Ala Ile Arg Met Asn Lys Asn 
                85                  90                  95      


Arg Ile Asn Asn Ala Phe Phe Leu Asn Asp Gln Thr Leu Glu Phe Leu 
            100                 105                 110         


Lys Ile Pro Ser Thr Leu Ala Pro Pro Met Asp Pro Ser Val Pro 
        115                 120                 125         


<210>  1460
<211>  446
<212>  PRT
<213>  Homo Sapiens

<400>  1460

Ala Pro Thr Trp Lys Asp Lys Thr Ala Ile Ser Glu Asn Leu Lys Ser 
1               5                   10                  15      


Phe Ser Glu Val Gly Glu Ile Asp Ala Asp Glu Glu Val Lys Lys Ala 
            20                  25                  30          


Leu Thr Gly Ile Lys Gln Met Lys Ile Met Met Glu Arg Lys Glu Lys 
        35                  40                  45              


Glu His Thr Asn Leu Met Ser Thr Leu Lys Lys Cys Arg Glu Glu Lys 
    50                  55                  60                  


Gln Glu Ala Leu Lys Leu Leu Asn Glu Val Gln Glu His Leu Glu Glu 
65                  70                  75                  80  


Glu Glu Arg Leu Cys Arg Glu Ser Leu Ala Asp Ser Trp Gly Glu Cys 
                85                  90                  95      


Arg Ser Cys Leu Glu Asn Asn Cys Met Arg Ile Tyr Thr Thr Cys Gln 
            100                 105                 110         


Pro Ser Trp Ser Ser Val Lys Asn Lys Ile Glu Arg Phe Phe Arg Lys 
        115                 120                 125             


Ile Tyr Gln Phe Leu Phe Pro Phe His Glu Asp Asn Glu Lys Asp Leu 
    130                 135                 140                 


Pro Ile Ser Glu Lys Leu Ile Glu Glu Asp Ala Gln Leu Thr Gln Met 
145                 150                 155                 160 


Glu Asp Val Phe Ser Gln Leu Thr Val Asp Val Asn Ser Leu Phe Asn 
                165                 170                 175     


Arg Ser Phe Asn Val Phe Arg Gln Met Gln Gln Glu Phe Asp Gln Thr 
            180                 185                 190         


Phe Gln Ser His Phe Ile Ser Asp Thr Asp Leu Thr Glu Pro Tyr Phe 
        195                 200                 205             


Phe Pro Ala Phe Ser Lys Glu Pro Met Thr Lys Ala Asp Leu Glu Gln 
    210                 215                 220                 


Cys Trp Asp Ile Pro Asn Phe Phe Gln Leu Phe Cys Asn Phe Ser Val 
225                 230                 235                 240 


Ser Ile Tyr Glu Ser Val Ser Glu Thr Ile Thr Lys Met Leu Lys Ala 
                245                 250                 255     


Ile Glu Asp Leu Pro Lys Gln Asp Lys Ala Pro Asp His Gly Gly Leu 
            260                 265                 270         


Ile Ser Lys Met Leu Pro Gly Gln Asp Arg Gly Leu Cys Gly Glu Leu 
        275                 280                 285             


Asp Gln Asn Leu Ser Arg Cys Phe Lys Phe His Glu Lys Cys Gln Lys 
    290                 295                 300                 


Cys Gln Ala His Leu Ser Glu Asp Cys Pro Asp Val Pro Ala Leu His 
305                 310                 315                 320 


Thr Glu Leu Asp Glu Ala Ile Arg Leu Val Asn Val Ser Asn Gln Gln 
                325                 330                 335     


Tyr Gly Gln Ile Leu Gln Met Thr Arg Lys His Leu Glu Asp Thr Ala 
            340                 345                 350         


Tyr Leu Val Glu Lys Met Arg Gly Gln Phe Gly Trp Val Ser Glu Leu 
        355                 360                 365             


Ala Asn Gln Ala Pro Glu Thr Glu Ile Ile Phe Asn Ser Ile Gln Val 
    370                 375                 380                 


Val Pro Arg Ile His Glu Gly Asn Ile Ser Lys Gln Asp Glu Thr Met 
385                 390                 395                 400 


Met Thr Asp Leu Ser Ile Leu Pro Ser Ser Asn Phe Thr Leu Lys Ile 
                405                 410                 415     


Pro Leu Glu Glu Ser Ala Glu Ser Ser Asn Phe Ile Gly Tyr Val Val 
            420                 425                 430         


Ala Lys Ala Leu Gln His Phe Lys Glu His Phe Lys Thr Trp 
        435                 440                 445     


<210>  1461
<211>  526
<212>  PRT
<213>  Homo Sapiens

<400>  1461

Glu Gly Ala Ala Pro Ile Ala Ile Thr Cys Phe Thr Arg Gly Leu Asp 
1               5                   10                  15      


Ile Arg Lys Glu Lys Ala Asp Val Leu Cys Pro Gly Gly Cys Pro Leu 
            20                  25                  30          


Glu Glu Phe Ser Val Tyr Gly Asn Ile Val Tyr Ala Ser Val Ser Ser 
        35                  40                  45              


Ile Cys Gly Ala Ala Val His Arg Gly Val Ile Ser Asn Ser Gly Gly 
    50                  55                  60                  


Pro Val Arg Val Tyr Ser Leu Pro Gly Arg Glu Asn Tyr Ser Ser Val 
65                  70                  75                  80  


Asp Ala Asn Gly Ile Gln Ser Gln Met Leu Ser Arg Trp Ser Ala Ser 
                85                  90                  95      


Phe Thr Val Thr Lys Gly Lys Ser Ser Thr Gln Glu Ala Thr Gly Gln 
            100                 105                 110         


Ala Val Ser Thr Ala His Pro Pro Thr Gly Lys Arg Leu Lys Lys Thr 
        115                 120                 125             


Pro Glu Lys Lys Thr Gly Asn Lys Asp Cys Lys Ala Asp Ile Ala Phe 
    130                 135                 140                 


Leu Ile Asp Gly Ser Phe Asn Ile Gly Gln Arg Arg Phe Asn Leu Gln 
145                 150                 155                 160 


Lys Asn Phe Val Gly Lys Val Ala Leu Met Leu Gly Ile Gly Thr Glu 
                165                 170                 175     


Gly Pro His Val Gly Leu Val Gln Ala Ser Glu His Pro Lys Ile Glu 
            180                 185                 190         


Phe Tyr Leu Lys Asn Phe Thr Ser Ala Lys Asp Val Leu Phe Ala Ile 
        195                 200                 205             


Lys Glu Val Gly Phe Arg Gly Gly Asn Ser Asn Thr Gly Lys Ala Leu 
    210                 215                 220                 


Lys His Thr Ala Gln Lys Phe Phe Thr Val Asp Ala Gly Val Arg Lys 
225                 230                 235                 240 


Gly Ile Pro Lys Val Val Val Val Phe Ile Asp Gly Trp Pro Ser Asp 
                245                 250                 255     


Asp Ile Glu Glu Ala Gly Ile Val Ala Arg Glu Phe Gly Val Asn Val 
            260                 265                 270         


Phe Ile Val Ser Val Ala Lys Pro Ile Pro Glu Glu Leu Gly Met Val 
        275                 280                 285             


Gln Asp Val Thr Phe Val Asp Lys Ala Val Cys Arg Asn Asn Gly Phe 
    290                 295                 300                 


Phe Ser Tyr His Met Pro Asn Trp Phe Gly Thr Thr Lys Tyr Val Lys 
305                 310                 315                 320 


Pro Leu Val Gln Lys Leu Cys Thr His Glu Gln Met Met Cys Ser Lys 
                325                 330                 335     


Thr Cys Tyr Asn Ser Val Asn Ile Ala Phe Leu Ile Asp Gly Ser Ser 
            340                 345                 350         


Ser Val Gly Asp Ser Asn Phe Arg Leu Met Leu Glu Phe Val Ser Asn 
        355                 360                 365             


Ile Ala Lys Thr Phe Glu Ile Ser Asp Ile Gly Ala Lys Ile Ala Ala 
    370                 375                 380                 


Val Gln Phe Thr Tyr Asp Gln Arg Thr Glu Phe Ser Phe Thr Asp Tyr 
385                 390                 395                 400 


Ser Thr Lys Glu Asn Val Leu Ala Val Ile Arg Asn Ile Arg Tyr Met 
                405                 410                 415     


Ser Gly Gly Thr Ala Thr Gly Asp Ala Ile Ser Phe Thr Val Arg Asn 
            420                 425                 430         


Val Phe Gly Pro Ile Arg Glu Ser Pro Asn Lys Asn Phe Leu Val Ile 
        435                 440                 445             


Val Thr Asp Gly Gln Ser Tyr Asp Asp Val Gln Gly Pro Ala Ala Ala 
    450                 455                 460                 


Ala His Asp Ala Gly Ile Thr Ile Phe Ser Val Gly Val Ala Trp Ala 
465                 470                 475                 480 


Pro Leu Asp Asp Leu Lys Asp Met Ala Ser Lys Pro Lys Glu Ser His 
                485                 490                 495     


Ala Phe Phe Thr Arg Glu Phe Thr Gly Leu Glu Pro Ile Val Ser Asp 
            500                 505                 510         


Val Ile Arg Gly Ile Cys Arg Asp Phe Leu Glu Ser Gln Gln 
        515                 520                 525     


<210>  1462
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  1462

Thr Gly Phe Leu Tyr Pro Phe Ser Ala Ala Ala Leu Gln Gln His Gly 
1               5                   10                  15      


Tyr Pro Glu Pro Gly Ala Gly Ser Pro Gly Ser Gly Tyr Ala Ser Arg 
            20                  25                  30          


Arg His Trp Cys His His Thr Val Thr Arg Thr Val Ser Cys Gln Val 
        35                  40                  45              


Gln Asn Gly Ser Glu Thr Val Val Gln Arg Val Tyr Gln Ser Cys Arg 
    50                  55                  60                  


Trp Pro Gly Pro Cys Ala Asn Leu Val Ser Tyr Arg Thr Leu Ile Arg 
65                  70                  75                  80  


Pro Thr Tyr Arg Val Ser Tyr Arg Thr Val Thr Val Leu Glu Trp Arg 
                85                  90                  95      


Cys Cys Pro Gly Phe Thr Gly Ser Asn Cys Asp Glu Glu Cys Met Asn 
            100                 105                 110         


Cys Thr Arg Leu Ser Asp Met Ser Glu Arg Leu Thr Thr Leu Glu Ala 
        115                 120                 125             


Lys Val Leu Leu Leu Glu Ala Ala Glu Arg Pro Ser Ser Pro Asp Asn 
    130                 135                 140                 


Asp Leu Pro Ala Pro Glu Ser Thr Pro Pro Thr Trp Asn Glu Asp Phe 
145                 150                 155                 160 


Leu Pro Asp Ala Ile Pro Leu Ala His Pro Val Pro Arg Gln Arg Arg 
                165                 170                 175     


Pro Thr Gly Pro Ala Gly Pro Pro Gly Gln Thr Gly Pro Pro Gly Pro 
            180                 185                 190         


Ala Gly Pro Pro Gly Ser Lys Gly Asp Arg Gly Gln Thr Gly Glu Lys 
        195                 200                 205             


Gly Pro Ala Gly Pro Pro Gly Leu Leu Gly Pro Pro Gly Pro Arg Gly 
    210                 215                 220                 


Leu Pro Gly Glu Met Gly Arg Pro Gly Pro Pro Gly Pro Pro Gly Pro 
225                 230                 235                 240 


Ala Gly Asn Pro Gly Pro Ser Pro Asn Ser Pro Gln Gly Ala Leu Tyr 
                245                 250                 255     


Ser Leu Gln Pro Pro Thr Asp Lys Asp Asn Gly Asp Ser Arg Leu Ala 
            260                 265                 270         


Ser Ala Ile Val Asp Thr Val Leu Ala Gly Val Pro Gly Pro Arg Gly 
        275                 280                 285             


Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Arg Gly Pro Pro Gly Pro 
    290                 295                 300                 


Pro Gly Thr Pro Gly Ser Gln Gly Leu Ala Gly Glu Arg Gly Thr Val 
305                 310                 315                 320 


Gly Pro Ser Gly Glu Pro Gly Val Lys Gly Glu Glu Gly Glu Lys Ala 
                325                 330                 335     


Ala Thr Ala Glu Gly Glu Gly Val Gln Gln Leu Arg Glu Ala Leu Lys 
            340                 345                 350         


Ile Leu Ala Glu Arg Val Leu Ile Leu Glu His Met Ile Gly Ile His 
        355                 360                 365             


Asp Pro Leu Ala Ser Pro Glu Gly Gly Ser Gly Gln Asp Ala Ala Leu 
    370                 375                 380                 


Arg Ala Asn Leu Lys Met Lys Arg Gly Gly Ala Gln Pro Asp Gly Val 
385                 390                 395                 400 


Leu Ala Ala Leu Leu Gly Pro Asp Pro Gly Gln Lys Ser Val Asp Gln 
                405                 410                 415     


Ala Ser Ser Arg Lys 
            420     


<210>  1463
<211>  537
<212>  PRT
<213>  Homo Sapiens

<400>  1463

Asp Gln Cys Asn Val Pro Glu Trp Leu Pro Phe Ala Arg Pro Thr Asn 
1               5                   10                  15      


Leu Thr Asp Asp Phe Glu Phe Pro Ile Gly Thr Tyr Leu Asn Tyr Glu 
            20                  25                  30          


Cys Arg Pro Gly Tyr Ser Gly Arg Pro Phe Ser Ile Ile Cys Leu Lys 
        35                  40                  45              


Asn Ser Val Trp Thr Ser Ala Lys Asp Lys Cys Lys Arg Lys Ser Cys 
    50                  55                  60                  


Arg Asn Pro Pro Asp Pro Val Asn Gly Met Ala His Val Ile Lys Asp 
65                  70                  75                  80  


Ile Gln Phe Arg Ser Gln Ile Lys Tyr Ser Cys Pro Lys Gly Tyr Arg 
                85                  90                  95      


Leu Ile Gly Ser Ser Ser Ala Thr Cys Ile Ile Ser Gly Asn Thr Val 
            100                 105                 110         


Ile Trp Asp Asn Lys Thr Pro Val Cys Asp Arg Ile Ile Cys Gly Leu 
        115                 120                 125             


Pro Pro Thr Ile Ala Asn Gly Asp Phe Thr Ser Ile Ser Arg Glu Tyr 
    130                 135                 140                 


Phe His Tyr Gly Ser Val Val Thr Tyr His Cys Asn Leu Gly Ser Arg 
145                 150                 155                 160 


Gly Lys Lys Val Phe Glu Leu Val Gly Glu Pro Ser Ile Tyr Cys Thr 
                165                 170                 175     


Ser Lys Asp Asp Gln Val Gly Ile Trp Ser Gly Pro Ala Pro Gln Cys 
            180                 185                 190         


Ile Ile Pro Asn Lys Cys Thr Pro Pro Asn Val Glu Asn Gly Ile Leu 
        195                 200                 205             


Val Ser Asp Asn Arg Ser Leu Phe Ser Leu Asn Glu Val Val Glu Phe 
    210                 215                 220                 


Arg Cys Gln Pro Gly Phe Gly Met Lys Gly Pro Ser His Val Lys Cys 
225                 230                 235                 240 


Gln Ala Leu Asn Lys Trp Glu Pro Glu Leu Pro Ser Cys Ser Arg Val 
                245                 250                 255     


Cys Gln Pro Pro Pro Asp Val Leu His Ala Glu Arg Thr Gln Arg Asp 
            260                 265                 270         


Lys Asp Asn Phe Ser Pro Gly Gln Glu Val Phe Tyr Ser Cys Glu Pro 
        275                 280                 285             


Gly Tyr Asp Leu Arg Gly Ser Thr Tyr Leu His Cys Thr Pro Gln Gly 
    290                 295                 300                 


Asp Trp Ser Pro Ala Ala Pro Arg Cys Glu Val Lys Ser Cys Asp Asp 
305                 310                 315                 320 


Phe Leu Gly Gln Leu Pro Asn Gly His Val Leu Phe Pro Leu Asn Leu 
                325                 330                 335     


Gln Leu Gly Ala Lys Val Asp Phe Val Cys Asp Glu Gly Phe Gln Leu 
            340                 345                 350         


Lys Gly Ser Ser Ala Ser Tyr Cys Val Leu Ala Gly Met Glu Ser Leu 
        355                 360                 365             


Trp Asn Ser Ser Val Pro Val Cys Glu Arg Lys Ser Cys Glu Thr Pro 
    370                 375                 380                 


Pro Val Pro Val Asn Gly Met Val His Val Ile Thr Asp Ile His Val 
385                 390                 395                 400 


Gly Ser Arg Ile Asn Tyr Ser Cys Thr Thr Gly His Arg Leu Ile Gly 
                405                 410                 415     


His Ser Ser Ala Glu Cys Ile Leu Ser Gly Asn Thr Ala His Trp Ser 
            420                 425                 430         


Met Lys Pro Pro Ile Cys Gln Gln Ile Phe Cys Pro Asn Pro Pro Ala 
        435                 440                 445             


Ile Leu Asn Gly Arg His Thr Gly Thr Pro Leu Gly Asp Ile Pro Tyr 
    450                 455                 460                 


Gly Lys Glu Val Ser Tyr Thr Cys Asp Pro His Pro Asp Arg Gly Met 
465                 470                 475                 480 


Thr Phe Asn Leu Ile Gly Glu Ser Thr Ile Arg Arg Thr Ser Glu Pro 
                485                 490                 495     


His Gly Asn Gly Val Trp Ser Ser Pro Ala Pro Arg Cys Glu Leu Pro 
            500                 505                 510         


Val Gly Ala Gly Ser His Asp Ala Leu Ile Val Gly Lys Phe Tyr Glu 
        515                 520                 525             


Val Phe Ala Glu Glu Phe Cys His Leu 
    530                 535         


<210>  1464
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  1464

Lys Lys Lys Ser Ala Arg Asp Gln Phe Asn Lys Leu Val Thr Asp Leu 
1               5                   10                  15      


Pro Asn Val Gln Glu Glu Ile Val Asn Ile His Asn Ala Leu Arg Arg 
            20                  25                  30          


Arg Val Val Pro Pro Ala Ser Asn Met Leu Lys Met Ser Trp Ser Glu 
        35                  40                  45              


Glu Ala Ala Gln Asn Ala Arg Ile Phe Ser Lys Tyr Cys Asp Met Thr 
    50                  55                  60                  


Glu Ser Asn Pro Leu Glu Arg Arg Leu Pro Asn Thr Phe Cys Gly Glu 
65                  70                  75                  80  


Asn Met His Met Thr Ser Tyr Pro Val Ser Trp Ser Ser Val Ile Gly 
                85                  90                  95      


Val Trp Tyr Ser Glu Ser Thr Ser Phe Lys His Gly Glu Trp Thr Thr 
            100                 105                 110         


Thr Asp Asp Asp Ile Thr Thr Asp His Tyr Thr Gln Ile Val Trp Ala 
        115                 120                 125             


Thr Ser Tyr Leu Ile Gly Cys Ala Ile Ala Ser Cys Arg Gln Gln Gly 
    130                 135                 140                 


Ser Pro Arg Tyr Leu Tyr Val Cys His Tyr Cys His Glu Gly Asn Asp 
145                 150                 155                 160 


Pro Glu Thr Lys Asn Glu Pro Tyr Lys Thr Gly Val Pro Cys Glu Ala 
                165                 170                 175     


Cys Pro Ser Asn Cys Glu Asp Lys Leu Cys Thr Asn Pro Cys Ile Tyr 
            180                 185                 190         


Tyr Asp Glu Tyr Phe Asp Cys Asp Ile Gln Val His Tyr Leu Gly Cys 
        195                 200                 205             


Asn His Ser Thr Thr Ile Leu Phe Cys Lys Ala Thr Cys Leu Cys Asp 
    210                 215                 220                 


Thr Glu Ile Lys 
225             


<210>  1465
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  1465

Gly Pro Ser Pro Asp Thr Cys Ser Gln Asp Leu Asn Ser Arg Val Lys 
1               5                   10                  15      


Pro Gly Phe Pro Lys Thr Ile Lys Thr Asn Asp Pro Gly Val Leu Gln 
            20                  25                  30          


Ala Ala Arg Tyr Ser Val Glu Lys Phe Asn Asn Cys Thr Asn Asp Met 
        35                  40                  45              


Phe Leu Phe Lys Glu Ser Arg Ile Thr Arg Ala Leu Val Gln Ile Val 
    50                  55                  60                  


Lys Gly Leu Lys Tyr Met Leu Glu Val Glu Ile Gly Arg Thr Thr Cys 
65                  70                  75                  80  


Lys Lys Asn Gln His Leu Arg Leu Asp Asp Cys Asp Phe Gln Thr Asn 
                85                  90                  95      


His Thr Leu Lys Gln Thr Leu Ser Cys Tyr Ser Glu Val Trp Val Val 
            100                 105                 110         


Pro Trp Leu Gln His Phe Glu Val Pro Val Leu Arg Cys His 
        115                 120                 125     


<210>  1466
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1466

Trp Arg Phe Gln Glu Glu Glu Glu Trp Asn Asp Gln Lys Gln Ile Ala 
1               5                   10                  15      


Val Tyr Leu Pro Pro Thr Leu Glu Phe Ala Val Tyr Thr Phe Asn Lys 
            20                  25                  30          


Gln Ser Lys Asp Trp Tyr Ala Tyr Lys Leu Val Pro Val Leu Ala Ser 
        35                  40                  45              


Trp Lys Glu Gln Gly Tyr Asp Lys Met Thr Phe Ser Met Asn Leu Gln 
    50                  55                  60                  


Leu Gly Arg Thr Met Cys Gly Lys Phe Glu Asp Asp Ile Asp Asn Cys 
65                  70                  75                  80  


Pro Phe Gln Glu Ser Pro Glu Leu Asn Asn Thr Cys Thr Cys Phe Phe 
                85                  90                  95      


Thr Ile Gly Ile Glu Pro Trp Arg Thr Arg Phe Asp Leu Trp Asn Lys 
            100                 105                 110         


Thr Cys Ser Gly Gly His Ser 
        115                 


<210>  1467
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  1467

Arg Arg Phe Gln Arg Asn Thr Gly Glu Met Ser Ser Asn Ser Thr Ala 
1               5                   10                  15      


Leu Ala Leu Val Arg Pro Ser Ser Ser Gly Leu Ile Asn Ser Asn Thr 
            20                  25                  30          


Asp Asn Asn Leu Ala Val Tyr Asp Leu Ser Arg Asp Ile Leu Asn Asn 
        35                  40                  45              


Phe Pro His Ser Ile Ala Arg Gln Lys Arg Ile Leu Val Asn Leu Ser 
    50                  55                  60                  


Met Val Glu Asn Lys Leu Val Glu Leu Glu His Thr Leu Leu Ser Lys 
65                  70                  75                  80  


Gly Phe Arg Gly Ala Ser Pro His Arg Lys Ser Thr 
                85                  90          


<210>  1468
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  1468

Met Ser Arg Arg Glu Gly Ser Leu Glu Asp Pro Gln Thr Asp Ser Ser 
1               5                   10                  15      


Val Ser Leu Leu Pro His Leu Glu Ala Lys Ile Arg Gln Thr His Ser 
            20                  25                  30          


Leu Ala His Leu Leu Thr Lys Tyr Ala Glu Gln Leu Leu Gln Glu Tyr 
        35                  40                  45              


Val Gln Leu Gln Gly Asp Pro Phe Gly Leu Pro Ser Phe Ser Pro Pro 
    50                  55                  60                  


Arg Leu Pro Val Ala Gly Leu Ser Ala Pro Ala Pro Ser His Ala Gly 
65                  70                  75                  80  


Leu Pro Val His Glu Arg Leu Arg Leu Asp Ala Ala Ala Leu Ala Ala 
                85                  90                  95      


Leu Pro Pro Leu Leu Asp Ala Val Cys Arg Arg Gln Ala Glu Leu Asn 
            100                 105                 110         


Pro Arg Ala Pro Arg Leu Leu Arg Arg Leu Glu Asp Ala Ala Arg Gln 
        115                 120                 125             


Ala Arg Ala Leu Gly Ala Ala Val Glu Ala Leu Leu Ala Ala Leu Gly 
    130                 135                 140                 


Ala Ala Asn Arg Gly Pro Arg Ala Glu Pro Pro Ala Ala Thr Ala Ser 
145                 150                 155                 160 


Ala Ala Ser Ala Thr Gly Val Phe Pro Ala Lys Val Leu Gly Leu Arg 
                165                 170                 175     


Val Cys Gly Leu Tyr Arg Glu Trp Leu Ser Arg Thr Glu Gly Asp Leu 
            180                 185                 190         


Gly Gln Leu Leu Pro Gly Gly Ser Ala 
        195                 200     


<210>  1469
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  1469

Ala Pro Pro Glu Trp Asp Trp Arg Ser Lys Gly Ala Val Thr Lys Val 
1               5                   10                  15      


Lys Asp Gln Gly Met Cys Gly Ser Cys Trp Ala Phe Ser Val Thr Gly 
            20                  25                  30          


Asn Val Glu Gly Gln Trp Phe Leu Asn Gln Gly Thr Leu Leu Ser Leu 
        35                  40                  45              


Ser Glu Gln Glu Leu Leu Asp Cys Asp Lys Met Asp Lys Ala Cys Met 
    50                  55                  60                  


Gly Gly Leu Pro Ser Asn Ala Tyr Ser Ala Ile Lys Asn Leu Gly Gly 
65                  70                  75                  80  


Leu Glu Thr Glu Asp Asp Tyr Ser Tyr Gln Gly His Met Gln Ser Cys 
                85                  90                  95      


Asn Phe Ser Ala Glu Lys Ala Lys Val Tyr Ile Asn Asp Ser Val Glu 
            100                 105                 110         


Leu Ser Gln Asn Glu Gln Lys Leu Ala Ala Trp Leu Ala Lys Arg Gly 
        115                 120                 125             


Pro Ile Ser Val Ala Ile Asn Ala Phe Gly Met Gln Phe Tyr Arg His 
    130                 135                 140                 


Gly Ile Ser Arg Pro Leu Arg Pro Leu Cys Ser Pro Trp Leu Ile Asp 
145                 150                 155                 160 


His Ala Val Leu Leu Val Gly Tyr Gly Asn Arg Ser Asp Val Pro Phe 
                165                 170                 175     


Trp Ala Ile Lys Asn Ser Trp Gly Thr Asp Trp Gly Glu Lys Gly Tyr 
            180                 185                 190         


Tyr Tyr Leu His Arg Gly Ser Gly Ala Cys Gly Val Asn Thr Met Ala 
        195                 200                 205             


Ser Ser Ala Val Val Asp 
    210                 


<210>  1470
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  1470

Leu Pro Asp Ser Val Asp Trp Arg Glu Lys Gly Cys Val Thr Glu Val 
1               5                   10                  15      


Lys Tyr Gln Gly Ser Cys Gly Ala Cys Trp Ala Phe Ser Ala Val Gly 
            20                  25                  30          


Ala Leu Glu Ala Gln Leu Lys Leu Lys Thr Gly Lys Leu Val Ser Leu 
        35                  40                  45              


Ser Ala Gln Asn Leu Val Asp Cys Ser Thr Glu Lys Tyr Gly Asn Lys 
    50                  55                  60                  


Gly Cys Asn Gly Gly Phe Met Thr Thr Ala Phe Gln Tyr Ile Ile Asp 
65                  70                  75                  80  


Asn Lys Gly Ile Asp Ser Asp Ala Ser Tyr Pro Tyr Lys Ala Met Asp 
                85                  90                  95      


Gln Lys Cys Gln Tyr Asp Ser Lys Tyr Arg Ala Ala Thr Cys Ser Lys 
            100                 105                 110         


Tyr Thr Glu Leu Pro Tyr Gly Arg Glu Asp Val Leu Lys Glu Ala Val 
        115                 120                 125             


Ala Asn Lys Gly Pro Val Ser Val Gly Val Asp Ala Arg His Pro Ser 
    130                 135                 140                 


Phe Phe Leu Tyr Arg Ser Gly Val Tyr Tyr Glu Pro Ser Cys Thr Gln 
145                 150                 155                 160 


Asn Val Asn His Gly Val Leu Val Val Gly Tyr Gly Asp Leu Asn Gly 
                165                 170                 175     


Lys Glu Tyr Trp Leu Val Lys Asn Ser Trp Gly His Asn Phe Gly Glu 
            180                 185                 190         


Glu Gly Tyr Ile Arg Met Ala Arg Asn Lys Gly Asn His Cys Gly Ile 
        195                 200                 205             


Ala Ser Phe Pro Ser Tyr Pro Glu Ile 
    210                 215         


<210>  1471
<211>  249
<212>  PRT
<213>  Homo Sapiens

<400>  1471

Val Pro Phe Ser Cys Asp Trp Arg Lys Val Ala Ser Ala Ile Ser Pro 
1               5                   10                  15      


Ile Lys Asp Gln Lys Asn Cys Asn Cys Cys Trp Ala Met Ala Ala Ala 
            20                  25                  30          


Gly Asn Ile Glu Thr Leu Trp Arg Ile Ser Phe Trp Asp Phe Val Asp 
        35                  40                  45              


Val Ser Val Gln Glu Leu Leu Asp Cys Gly Arg Cys Gly Asp Gly Cys 
    50                  55                  60                  


His Gly Gly Phe Val Trp Asp Ala Phe Ile Thr Val Leu Asn Asn Ser 
65                  70                  75                  80  


Gly Leu Ala Ser Glu Lys Asp Tyr Pro Phe Gln Gly Lys Val Arg Ala 
                85                  90                  95      


His Arg Cys His Pro Lys Lys Tyr Gln Lys Val Ala Trp Ile Gln Asp 
            100                 105                 110         


Phe Ile Met Leu Gln Asn Asn Glu His Arg Ile Ala Gln Tyr Leu Ala 
        115                 120                 125             


Thr Tyr Gly Pro Ile Thr Val Thr Ile Asn Met Lys Pro Leu Gln Leu 
    130                 135                 140                 


Tyr Arg Lys Gly Val Ile Lys Ala Thr Pro Thr Thr Cys Asp Pro Gln 
145                 150                 155                 160 


Leu Val Asp His Ser Val Leu Leu Val Gly Phe Gly Ser Val Lys Ser 
                165                 170                 175     


Glu Glu Gly Ile Trp Ala Glu Thr Val Ser Ser Gln Ser Gln Pro Gln 
            180                 185                 190         


Pro Pro His Pro Thr Pro Tyr Trp Ile Leu Lys Asn Ser Trp Gly Ala 
        195                 200                 205             


Gln Trp Gly Glu Lys Gly Tyr Phe Arg Leu His Arg Gly Ser Asn Thr 
    210                 215                 220                 


Cys Gly Ile Thr Lys Phe Pro Leu Thr Ala Arg Val Gln Lys Pro Asp 
225                 230                 235                 240 


Met Lys Pro Arg Val Ser Cys Pro Pro 
                245                 


<210>  1472
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  1472

Arg Leu Leu Leu Leu Pro Arg Val Leu Leu Thr Met Ala Ser Gly Ser 
1               5                   10                  15      


Pro Pro Thr Gln Pro Ser Pro Ala Ser Asp Ser Gly Ser Gly Tyr Val 
            20                  25                  30          


Pro Gly Ser Val Ser Ala Ala Phe Val Thr Cys Pro Asn Glu Lys Val 
        35                  40                  45              


Ala Lys Glu Ile Ala Arg Ala Val Val Glu Lys Arg Leu Ala Ala Cys 
    50                  55                  60                  


Val Asn Leu Ile Pro Gln Ile Thr Ser Ile Tyr Glu Trp Lys Gly Lys 
65                  70                  75                  80  


Ile Glu Glu Asp Ser Glu Val Leu Met Met Ile Lys Thr Gln Ser Ser 
                85                  90                  95      


Leu Val Pro Ala Leu Thr Asp Phe Val Arg Ser Val His Pro Tyr Glu 
            100                 105                 110         


Val Ala Glu Val Ile Ala Leu Pro Val Glu Gln Gly Asn Phe Pro Tyr 
        115                 120                 125             


Leu Gln Trp Val Arg Gln Val Thr Glu Ser Val Ser Asp Ser Ile Thr 
    130                 135                 140                 


Val Leu Pro 
145         


<210>  1473
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  1473

Leu His Leu Asp Val Gln Arg Gly Arg Arg Val Ser Pro Gly Cys Pro 
1               5                   10                  15      


Ile Val Gly Thr His Val Cys Pro Val Arg Val Gln Gln Glu Ile Asp 
            20                  25                  30          


Asp Val Ile Gly Gln Val Arg Arg Pro Glu Met Gly Asp Gln Ala His 
        35                  40                  45              


Met Pro Cys Thr Thr Ala Val Ile His Glu Val Gln His Phe Gly Asp 
    50                  55                  60                  


Ile Val Pro Leu Gly Val Thr His Met Thr Ser Arg Asp Ile Glu Val 
65                  70                  75                  80  


Gln Gly Phe Arg Ile Pro Lys Gly Thr Thr Leu Ile Thr Asn Leu Ser 
                85                  90                  95      


Ser Val Leu Lys Asp Glu Ala Val Trp Lys Lys Pro Phe Arg Phe His 
            100                 105                 110         


Pro Glu His Phe Leu Asp Ala Gln Gly His Phe Val Lys Pro Glu Ala 
        115                 120                 125             


Phe Leu Pro Phe Ser Ala Gly Arg Arg Ala Cys Leu Gly Glu Pro Leu 
    130                 135                 140                 


Ala Arg Met Glu Leu Phe Leu Phe Phe Thr Ser Leu Leu Gln His Phe 
145                 150                 155                 160 


Ser Phe Ser Val Ala Ala Gly Gln Pro Arg Pro Ser His Ser Arg Val 
                165                 170                 175     


Val Ser Phe Leu Val Thr Pro Ser Pro Tyr Glu Leu Cys Ala Val Pro 
            180                 185                 190         


Arg 
    


<210>  1474
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  1474

Tyr Asp Pro Glu Ala Ala Ser Ala Pro Gly Ser Gly Asn Pro Cys His 
1               5                   10                  15      


Glu Ala Ser Ala Ala Gln Lys Glu Asn Ala Gly Glu Asp Pro Gly Leu 
            20                  25                  30          


Ala Arg Gln Ala Pro Lys Pro Arg Lys Gln Arg Ser Ser Leu Leu Glu 
        35                  40                  45              


Lys Gly Leu Asp Gly Ala Lys Lys Ala Val Gly Gly Leu Gly Lys Leu 
    50                  55                  60                  


Gly Lys Asp Ala Val Glu Asp Leu Glu Ser Val Gly Lys Gly Ala Val 
65                  70                  75                  80  


His Asp Val Lys Asp Val Leu Asp Ser Val Leu 
                85                  90      


<210>  1475
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  1475

Asn Trp Tyr Val Lys Lys Cys Leu Asn Asp Val Gly Ile Cys Lys Lys 
1               5                   10                  15      


Lys Cys Lys Pro Glu Glu Met His Val Lys Asn Gly Trp Ala Met Cys 
            20                  25                  30          


Gly Lys Gln Arg Asp Cys Cys Val Pro Ala Asp Arg Arg Ala Asn Tyr 
        35                  40                  45              


Pro Val Phe Cys Val Gln Thr Lys Thr Thr Arg Ile Ser Thr Val Thr 
    50                  55                  60                  


Ala Thr Thr Ala Thr Thr Thr Leu Met Met Thr Thr Ala Ser Met Ser 
65                  70                  75                  80  


Ser Met Ala Pro Thr Pro Val Ser Pro Thr Gly 
                85                  90      


<210>  1476
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  1476

Ala Arg Leu Lys Lys Cys Phe Asn Lys Val Thr Gly Tyr Cys Arg Lys 
1               5                   10                  15      


Lys Cys Lys Val Gly Glu Arg Tyr Glu Ile Gly Cys Leu Ser Gly Lys 
            20                  25                  30          


Leu Cys Cys Ala Asn Asp Glu Glu Glu Lys Lys His Val Ser Phe Lys 
        35                  40                  45              


Lys Pro His Gln His Ser Gly Glu Lys Leu Ser Val Leu Gln Asp Tyr 
    50                  55                  60                  


Ile Ile Leu Pro Thr Ile Thr Ile Phe Thr Val 
65                  70                  75  


<210>  1477
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  1477

Trp Asn Tyr Leu Phe Asp Phe His Pro His Arg Val Leu Val Val Gly 
1               5                   10                  15      


Ala Phe Ala Asn Phe Cys Thr Glu Pro Thr Gly Cys Ser Cys Leu Phe 
            20                  25                  30          


Pro Lys Leu Pro Pro His Leu Leu Met Leu Pro Cys Trp Phe His Leu 
        35                  40                  45              


Leu Phe Phe Gln Asp Tyr Ile Met Ser Gly Ala Ser Ala Leu Pro Pro 
    50                  55                  60                  


Gly Leu Val Ser Phe Val Lys Ala Pro Leu Pro Gln Trp Trp Pro Gly 
65                  70                  75                  80  


Gly Cys Pro Gly Val Gly Gly Pro Leu Gln Ala Leu Glu Ala Lys Pro 
                85                  90                  95      


Gly Gln Leu Ser Leu Pro Ile Arg Asn Gln Lys Arg Leu Val Lys Ser 
            100                 105                 110         


Ala Leu Glu Leu Gly Glu Asn Glu Leu Phe Gln Gln Phe Pro Asn Pro 
        115                 120                 125             


Gln Ser Ser Trp Val Gln Arg Thr Gln Glu Ala Leu Arg Pro Leu Leu 
    130                 135                 140                 


Ser Val Ala Leu Gln Leu Phe Leu Gly Arg Arg Gly Leu Pro Leu Pro 
145                 150                 155                 160 


Phe Arg Ala Pro Ile Arg Thr Val Val Gly Ser Ala Ile Pro Val Gln 
                165                 170                 175     


Gln Ser Pro Pro Pro Ser Pro Ala Gln Val Asp Thr Leu Gln Ala Arg 
            180                 185                 190         


Tyr Val Gly Arg Leu Thr Gln Leu Phe Glu Glu His Gln Ala Arg Tyr 
        195                 200                 205             


Gly Val Pro Ala Asp Arg His Leu Val Leu Thr Glu Ala Arg Pro Thr 
    210                 215                 220                 


Ala Trp Pro Arg Leu Ser Ala Gly 
225                 230         


<210>  1478
<211>  230
<212>  PRT
<213>  Homo Sapiens

<400>  1478

Leu Val Gln Gln Gly Leu Lys Val Val Gly Cys Ala Arg Thr Val Gly 
1               5                   10                  15      


Asn Ile Glu Glu Leu Ala Ala Glu Cys Lys Ser Ala Gly Tyr Pro Gly 
            20                  25                  30          


Thr Leu Ile Pro Tyr Arg Cys Asp Leu Ser Asn Glu Glu Asp Ile Leu 
        35                  40                  45              


Ser Met Phe Ser Ala Ile Arg Ser Gln His Ser Gly Val Asp Ile Cys 
    50                  55                  60                  


Ile Asn Asn Ala Gly Leu Ala Arg Pro Asp Thr Leu Leu Ser Gly Ser 
65                  70                  75                  80  


Thr Ser Gly Trp Lys Asp Met Phe Asn Val Asn Val Leu Ala Leu Ser 
                85                  90                  95      


Ile Cys Thr Arg Glu Ala Tyr Gln Ser Met Lys Glu Arg Asn Val Asp 
            100                 105                 110         


Asp Gly His Ile Ile Asn Ile Asn Ser Met Ser Gly His Arg Val Leu 
        115                 120                 125             


Pro Leu Ser Val Thr His Phe Tyr Ser Ala Thr Lys Tyr Ala Val Thr 
    130                 135                 140                 


Ala Leu Thr Glu Gly Leu Arg Gln Glu Leu Arg Glu Ala Gln Thr His 
145                 150                 155                 160 


Ile Arg Ala Thr Cys Ile Ser Pro Gly Val Val Glu Thr Gln Phe Ala 
                165                 170                 175     


Phe Lys Leu His Asp Lys Asp Pro Glu Lys Ala Ala Ala Thr Tyr Glu 
            180                 185                 190         


Gln Met Lys Cys Leu Lys Pro Glu Asp Val Ala Glu Ala Val Ile Tyr 
        195                 200                 205             


Val Leu Ser Thr Pro Ala His Ile Gln Ile Gly Asp Ile Gln Met Arg 
    210                 215                 220                 


Pro Thr Glu Gln Val Thr 
225                 230 


<210>  1479
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  1479

Pro Pro Cys Gly Gly Met Gly Asn Leu Arg Gly Arg Thr Ala Val Val 
1               5                   10                  15      


Thr Gly Ala Asn Ser Gly Ile Gly Lys Met Thr Ala Leu Glu Leu Ala 
            20                  25                  30          


Arg Arg Gly Ala Arg Val Val Leu Ala Cys Arg Ser Gln Glu Arg Gly 
        35                  40                  45              


Glu Ala Ala Ala Phe Asp Leu Arg Gln Glu Ser Gly Asn Asn Glu Val 
    50                  55                  60                  


Ile Phe Met Ala Leu Asp Leu Ala Ser Leu Ala Ser Val Arg Ala Phe 
65                  70                  75                  80  


Ala Thr Ala Phe Leu Ser Ser Glu Pro Arg Leu Asp Ile Leu Ile His 
                85                  90                  95      


Asn Ala Gly Ile Ser Ser Cys Gly Arg Thr Arg Glu Ala Phe Asn Leu 
            100                 105                 110         


Leu Leu Arg Val Asn His Ile Gly Pro Phe Leu Leu Thr His Leu Leu 
        115                 120                 125             


Leu Pro Cys Leu Lys Ala Cys Ala Pro Ser Arg Val Val Val Val Ala 
    130                 135                 140                 


Ser Ala Ala His Cys Arg Gly Arg Leu Asp Phe Lys Arg Leu Asp Arg 
145                 150                 155                 160 


Pro Val Val Gly Trp Arg Gln Glu Leu Arg Ala Tyr Ala Asp Thr Lys 
                165                 170                 175     


Leu Ala Asn Val Leu Phe Ala Arg Glu Leu Ala Asn Gln Leu Glu Ala 
            180                 185                 190         


Thr Gly Val Thr Cys Tyr Ala Ala His Pro Gly Pro Val Asn Ser Glu 
        195                 200                 205             


Leu Phe Leu Arg His Val Pro Gly Trp Leu Arg Pro Leu Leu Arg Pro 
    210                 215                 220                 


Leu Ala Trp Leu Val Leu Arg Ala Pro Arg Gly Gly Ala Gln Thr Pro 
225                 230                 235                 240 


Leu Tyr Cys Ala Leu Gln Glu Gly Ile Glu Pro Leu Ser Gly Arg Tyr 
                245                 250                 255     


Phe Ala Asn Cys His Val Glu Glu Val Pro Pro Ala Ala Arg Asp Asp 
            260                 265                 270         


Arg Ala Ala His Arg Leu Trp Glu Ala Ser Lys Arg Leu Ala Gly Leu 
        275                 280                 285             


Gly Pro Gly Glu Asp Ala Glu Pro Asp Glu Asp Pro Gln Ser Glu Asp 
    290                 295                 300                 


Ser Glu Ala Pro Ser Ser Leu Ser Thr Pro His Pro Glu Glu Pro Thr 
305                 310                 315                 320 


Val Ser Gln Pro Tyr Pro Ser Pro Gln Ser Ser Pro Asp Leu Ser Lys 
                325                 330                 335     


Met Thr His Arg Ile Gln Ala Lys Val Glu Pro Glu Ile Gln Leu Ser 
            340                 345                 350         


<210>  1480
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  1480

Arg Met Thr Arg Arg Asp Pro Leu Thr Asn Lys Val Ala Leu Val Thr 
1               5                   10                  15      


Ala Ser Thr Asp Gly Ile Gly Phe Ala Ile Ala Arg Arg Leu Ala Gln 
            20                  25                  30          


Asp Arg Ala His Val Val Val Ser Ser Arg Lys Gln Gln Asn Val Asp 
        35                  40                  45              


Gln Ala Val Ala Thr Leu Gln Gly Glu Gly Leu Ser Val Thr Gly Thr 
    50                  55                  60                  


Val Cys His Val Gly Lys Ala Glu Asp Arg Glu Arg Leu Val Ala Met 
65                  70                  75                  80  


Ala Val Lys Leu His Gly Gly Ile Asp Ile Leu Val Ser Asn Ala Ala 
                85                  90                  95      


Val Asn Pro Phe Phe Gly Ser Leu Met Asp Val Thr Glu Glu Val Trp 
            100                 105                 110         


Asp Lys Thr Leu Asp Ile Asn Val Lys Ala Pro Ala Leu Met Thr Lys 
        115                 120                 125             


Ala Val Val Pro Glu Met Glu Lys Arg Gly Gly Gly Ser Val Val Ile 
    130                 135                 140                 


Val Ser Ser Ile Ala Ala Phe Ser Pro Ser Pro Gly Phe Ser Pro Tyr 
145                 150                 155                 160 


Asn Val Ser Lys Thr Ala Leu Leu Gly Leu Asn Asn Thr Leu Ala Ile 
                165                 170                 175     


Glu Leu Ala Pro Arg Asn Ile Arg Val Asn Cys Leu His Leu Asp Leu 
            180                 185                 190         


Ser Arg Leu Ala Ser Ala Gly Cys Ser Gly Trp Thr Arg Lys Lys Arg 
        195                 200                 205             


Lys Ala 
    210 


<210>  1481
<211>  302
<212>  PRT
<213>  Homo Sapiens

<400>  1481

Arg Lys Gly Lys Leu Lys Ile Glu Asp Ile Thr Asp Lys Tyr Ile Phe 
1               5                   10                  15      


Ile Thr Gly Cys Asp Ser Gly Phe Gly Asn Leu Ala Ala Arg Thr Phe 
            20                  25                  30          


Asp Lys Lys Gly Phe His Val Ile Ala Ala Cys Leu Thr Glu Ser Gly 
        35                  40                  45              


Ser Thr Ala Leu Lys Ala Glu Thr Ser Glu Arg Leu Arg Thr Val Leu 
    50                  55                  60                  


Leu Asp Val Thr Asp Pro Glu Asn Val Lys Arg Thr Ala Gln Trp Val 
65                  70                  75                  80  


Lys Asn Gln Val Gly Glu Lys Gly Leu Trp Gly Leu Ile Asn Asn Ala 
                85                  90                  95      


Gly Val Pro Gly Val Leu Ala Pro Thr Asp Trp Leu Thr Leu Glu Asp 
            100                 105                 110         


Tyr Arg Glu Pro Ile Glu Val Asn Leu Phe Gly Leu Ile Ser Val Thr 
        115                 120                 125             


Leu Asn Met Leu Pro Leu Val Lys Lys Ala Gln Gly Arg Val Ile Asn 
    130                 135                 140                 


Val Ser Ser Val Gly Gly Arg Leu Ala Ile Val Gly Gly Gly Tyr Thr 
145                 150                 155                 160 


Pro Ser Lys Tyr Ala Val Glu Gly Phe Asn Asp Ser Leu Arg Arg Asp 
                165                 170                 175     


Met Lys Ala Phe Gly Val His Val Ser Cys Ile Glu Pro Gly Leu Phe 
            180                 185                 190         


Lys Thr Asn Leu Ala Asp Pro Val Lys Val Ile Glu Lys Lys Leu Ala 
        195                 200                 205             


Ile Trp Glu Gln Leu Ser Pro Asp Ile Lys Gln Gln Tyr Gly Glu Gly 
    210                 215                 220                 


Tyr Ile Glu Lys Ser Leu Asp Lys Leu Lys Gly Asn Lys Ser Tyr Val 
225                 230                 235                 240 


Asn Met Asp Leu Ser Pro Val Val Glu Cys Met Asp His Ala Leu Thr 
                245                 250                 255     


Ser Leu Phe Pro Lys Thr His Tyr Ala Ala Gly Lys Asp Ala Lys Ile 
            260                 265                 270         


Phe Trp Ile Pro Leu Ser His Met Pro Ala Ala Leu Gln Asp Phe Leu 
        275                 280                 285             


Leu Leu Lys Gln Lys Ala Glu Leu Ala Asn Pro Lys Ala Val 
    290                 295                 300         


<210>  1482
<211>  402
<212>  PRT
<213>  Homo Sapiens

<400>  1482

Leu Pro Ala Ser Ser Leu Ser Ser Leu Val Pro Gln Val Arg Thr Ser 
1               5                   10                  15      


Tyr Asn Phe Gly Arg Thr Phe Leu Gly Leu Asp Lys Cys Asn Ala Cys 
            20                  25                  30          


Ile Gly Thr Ser Ile Cys Lys Lys Phe Phe Lys Glu Glu Ile Arg Ser 
        35                  40                  45              


Asp Asn Trp Leu Ala Ser His Leu Gly Leu Pro Pro Asp Ser Leu Leu 
    50                  55                  60                  


Ser Tyr Pro Ala Asn Tyr Ser Asp Asp Ser Lys Ile Trp Arg Pro Val 
65                  70                  75                  80  


Glu Ile Phe Arg Leu Val Ser Lys Tyr Gln Asn Glu Ile Ser Asp Arg 
                85                  90                  95      


Arg Ile Cys Ala Ser Ala Ser Ala Pro Lys Thr Cys Ser Ile Glu Arg 
            100                 105                 110         


Val Leu Arg Lys Thr Glu Arg Phe Gln Lys Trp Leu Gln Ala Lys Arg 
        115                 120                 125             


Leu Thr Pro Asp Leu Val Gln Gly Leu Ala Ser Pro Leu Leu Arg Cys 
    130                 135                 140                 


Pro Ser Gln Arg Leu Leu Asp Arg Val Val Arg Arg Tyr Ala Glu Val 
145                 150                 155                 160 


Ala Asp Ala Gly Ser Ile Phe Met Asp His Phe Thr Asp Arg Asp Lys 
                165                 170                 175     


Leu Arg Leu Leu Tyr Thr Leu Ala Val Asn Ser His Pro Ile Leu Leu 
            180                 185                 190         


Gln Ile Phe Pro Gly Ala Glu Gly Trp Pro Leu Pro Lys Tyr Leu Gly 
        195                 200                 205             


Ser Cys Gly Arg Phe Leu Val Ser Thr Ser Thr Arg Pro Leu Gln Glu 
    210                 215                 220                 


Phe Tyr Asp Ala Pro Pro Asp Gln Ala Ala Asp Leu Ala Tyr Gln Leu 
225                 230                 235                 240 


Leu Gly Val Leu Glu Ser Leu Arg Ser Asn Asp Leu Asn Tyr Phe Phe 
                245                 250                 255     


Tyr Phe Thr His Ile Asp Ala Gly Met Phe Gly Val Phe Asn Asn Gly 
            260                 265                 270         


His Leu Phe Ile Arg Asp Ala Ser Ala Val Gly Val Ile Asp Lys Gln 
        275                 280                 285             


Glu Gly Ser Gln Glu Ala Asn Arg Ala Gly Glu Asn Lys Asp Ile Phe 
    290                 295                 300                 


Ser Cys Leu Val Ser Gly Cys Gln Ala Gln Leu Pro Ser Cys Glu Ser 
305                 310                 315                 320 


Ile Ser Glu Lys Gln Ser Leu Val Leu Val Cys Gln Lys Leu Leu Pro 
                325                 330                 335     


Arg Leu Leu Gln Gly Arg Phe Pro Ser Pro Val Gln Asp Asp Ile Asp 
            340                 345                 350         


Ser Ile Leu Val Gln Cys Gly Asp Ser Ile Arg Pro Asp Pro Glu Val 
        355                 360                 365             


Leu Gly Ala Ala Ser Gln Leu Lys Asp Ile Leu Arg Pro Leu Arg Thr 
    370                 375                 380                 


Cys Asp Ser Arg Phe Ala Tyr Arg Tyr Pro Asp Cys Lys Tyr Asn Asp 
385                 390                 395                 400 


Lys Phe 
        


<210>  1483
<211>  431
<212>  PRT
<213>  Homo Sapiens

<400>  1483

Ala Tyr Thr Thr Pro Gly Pro Pro Arg Ala Leu Thr Thr Leu Gly Ala 
1               5                   10                  15      


Pro Arg Ala His Thr Met Pro Gly Thr Tyr Ala Pro Ser Thr Thr Leu 
            20                  25                  30          


Ser Ser Pro Ser Thr Gln Gly Leu Gln Glu Gln Ala Arg Ala Leu Met 
        35                  40                  45              


Arg Asp Phe Pro Leu Val Asp Gly His Asn Asp Leu Pro Leu Val Leu 
    50                  55                  60                  


Arg Gln Val Tyr Gln Lys Gly Leu Gln Asp Val Asn Leu Arg Asn Phe 
65                  70                  75                  80  


Ser Tyr Gly Gln Thr Ser Leu Asp Arg Leu Arg Asp Gly Leu Val Gly 
                85                  90                  95      


Ala Gln Phe Trp Ser Ala Tyr Val Pro Cys Gln Thr Gln Asp Arg Asp 
            100                 105                 110         


Ala Leu Arg Leu Thr Leu Glu Gln Ile Asp Leu Ile Arg Arg Met Cys 
        115                 120                 125             


Ala Ser Tyr Ser Glu Leu Glu Leu Val Thr Ser Ala Lys Ala Leu Asn 
    130                 135                 140                 


Asp Thr Gln Lys Leu Ala Cys Leu Ile Gly Val Glu Gly Gly His Ser 
145                 150                 155                 160 


Leu Asp Asn Ser Leu Ser Ile Leu Arg Thr Phe Tyr Met Leu Gly Val 
                165                 170                 175     


Arg Tyr Leu Thr Leu Thr His Thr Cys Asn Thr Pro Trp Ala Glu Ser 
            180                 185                 190         


Ser Ala Lys Gly Val His Ser Phe Tyr Asn Asn Ile Ser Gly Leu Thr 
        195                 200                 205             


Asp Phe Gly Glu Lys Val Val Ala Glu Met Asn Arg Leu Gly Met Met 
    210                 215                 220                 


Val Asp Leu Ser His Val Ser Asp Ala Val Ala Arg Arg Ala Leu Glu 
225                 230                 235                 240 


Val Ser Gln Ala Pro Val Ile Phe Ser His Ser Ala Ala Arg Gly Val 
                245                 250                 255     


Cys Asn Ser Ala Arg Asn Val Pro Asp Asp Ile Leu Gln Leu Leu Lys 
            260                 265                 270         


Lys Asn Gly Gly Val Val Met Val Ser Leu Ser Met Gly Val Ile Gln 
        275                 280                 285             


Cys Asn Pro Ser Ala Asn Val Ser Thr Val Ala Asp His Phe Asp His 
    290                 295                 300                 


Ile Lys Ala Val Ile Gly Ser Lys Phe Ile Gly Ile Gly Gly Asp Tyr 
305                 310                 315                 320 


Asp Gly Ala Gly Lys Phe Pro Gln Gly Leu Glu Asp Val Ser Thr Tyr 
                325                 330                 335     


Pro Val Leu Ile Glu Glu Leu Leu Ser Arg Gly Trp Ser Glu Glu Glu 
            340                 345                 350         


Leu Gln Gly Val Leu Arg Gly Asn Leu Leu Arg Val Phe Arg Gln Val 
        355                 360                 365             


Glu Lys Val Gln Glu Glu Asn Lys Trp Gln Ser Pro Leu Glu Asp Lys 
    370                 375                 380                 


Phe Pro Asp Glu Gln Leu Ser Ser Ser Cys His Ser Asp Leu Ser Arg 
385                 390                 395                 400 


Leu Arg Gln Arg Gln Ser Leu Thr Ser Gly Gln Glu Leu Thr Glu Ile 
                405                 410                 415     


Pro Ile His Trp Thr Ala Lys Leu Pro Ala Lys Trp Ser Val Ser 
            420                 425                 430     


<210>  1484
<211>  324
<212>  PRT
<213>  Homo Sapiens

<400>  1484

Gly Ala Leu Ala Pro Gly Thr Pro Ala Arg Asn Leu Pro Glu Asn His 
1               5                   10                  15      


Ile Asp Leu Pro Gly Pro Ala Leu Trp Thr Pro Gln Ala Ser His His 
            20                  25                  30          


Arg Arg Arg Gly Pro Gly Lys Lys Glu Trp Gly Pro Gly Leu Pro Ser 
        35                  40                  45              


Gln Ala Gln Asp Gly Ala Val Val Thr Ala Thr Arg Gln Ala Ser Arg 
    50                  55                  60                  


Leu Pro Glu Ala Glu Gly Leu Leu Pro Glu Gln Ser Pro Ala Gly Leu 
65                  70                  75                  80  


Leu Gln Asp Lys Asp Leu Leu Leu Gly Leu Ala Leu Pro Tyr Pro Glu 
                85                  90                  95      


Lys Glu Asn Arg Pro Pro Gly Trp Glu Arg Thr Arg Lys Arg Ser Arg 
            100                 105                 110         


Glu His Lys Arg Arg Arg Asp Arg Leu Arg Leu His Gln Gly Arg Ala 
        115                 120                 125             


Leu Val Arg Gly Pro Ser Ser Leu Met Lys Lys Ala Glu Leu Ser Glu 
    130                 135                 140                 


Ala Gln Val Leu Asp Ala Ala Met Glu Glu Ser Ser Thr Ser Leu Ala 
145                 150                 155                 160 


Pro Thr Met Phe Phe Leu Thr Thr Phe Glu Ala Ala Pro Ala Thr Glu 
                165                 170                 175     


Glu Ser Leu Ile Leu Pro Val Thr Ser Leu Arg Pro Gln Gln Ala Gln 
            180                 185                 190         


Pro Arg Ser Asp Gly Glu Val Met Pro Thr Leu Asp Met Ala Leu Phe 
        195                 200                 205             


Asp Trp Thr Asp Tyr Glu Asp Leu Lys Pro Asp Gly Trp Pro Ser Ala 
    210                 215                 220                 


Lys Lys Lys Glu Lys His Arg Gly Lys Leu Ser Ser Asp Gly Asn Glu 
225                 230                 235                 240 


Thr Ser Pro Ala Glu Gly Glu Pro Cys Asp His His Gln Asp Cys Leu 
                245                 250                 255     


Pro Gly Thr Cys Cys Asp Leu Arg Glu His Leu Cys Thr Pro His Asn 
            260                 265                 270         


Arg Gly Leu Asn Asn Lys Cys Phe Asp Asp Cys Met Cys Val Glu Gly 
        275                 280                 285             


Leu Arg Cys Tyr Ala Lys Phe His Arg Asn Arg Arg Val Thr Arg Arg 
    290                 295                 300                 


Lys Gly Arg Cys Val Glu Pro Glu Thr Ala Asn Gly Asp Gln Gly Ser 
305                 310                 315                 320 


Phe Ile Asn Val 
                


<210>  1485
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  1485

Leu Val Asn Asn Lys Gly Ser Ala Asn Ser Ser Ile Val Ile Gln Leu 
1               5                   10                  15      


Ser Thr Asn Asp Gly Glu Cys Val Thr Val Lys Pro Gly Thr Pro Ser 
            20                  25                  30          


Pro Ala Cys Pro Pro Thr Met Thr Thr Thr Ser Thr Val Pro Ala Ser 
        35                  40                  45              


Thr Ala Thr Glu Ser Thr Thr Ser Thr Ala Thr Ala Ala Thr Thr Ser 
    50                  55                  60                  


Thr Glu Pro Ile Thr Val Ala Pro Thr Asp His Leu 
65                  70                  75      


<210>  1486
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  1486

Leu Arg His Val Val Tyr Trp Asn Ser Ser Asn Pro Arg Leu Leu Arg 
1               5                   10                  15      


Gly Asp Ala Val Val Glu Leu Gly Leu Asn Asp Tyr Leu Asp Ile Val 
            20                  25                  30          


Cys Pro His Tyr Glu Gly Pro Gly Pro Pro Glu Gly Pro Glu Thr Phe 
        35                  40                  45              


Ala Leu Tyr Met Val Asp Trp Pro Gly Tyr Glu Ser Cys Gln Ala Glu 
    50                  55                  60                  


Gly Pro Arg Ala Tyr Lys Arg Trp Val Cys Ser Leu Pro Phe Gly His 
65                  70                  75                  80  


Val Gln Phe Ser Glu Lys Ile Gln Arg Phe Thr Pro Phe Ser Leu Gly 
                85                  90                  95      


Phe Glu Phe Leu Pro Gly Glu Thr Tyr Tyr Tyr Ile Ser Val Pro Thr 
            100                 105                 110         


Pro Glu Ser Ser Gly Gln Cys Leu Arg Leu Gln Val Ser Val Cys Cys 
        115                 120                 125             


Lys Glu Arg Lys Ser Glu Ser Ala His Pro Val Gly Ser Pro Gly Glu 
    130                 135                 140                 


Ser 
145 


<210>  1487
<211>  479
<212>  PRT
<213>  Homo Sapiens

<400>  1487

Arg Leu Val Gly Glu Glu Glu Ala Gly Phe Gly Glu Cys Asp Lys Phe 
1               5                   10                  15      


Phe Tyr Ala Gly Thr Pro Pro Ala Gly Leu Ala Ala Asp Ser His Val 
            20                  25                  30          


Lys Ile Cys Gln Arg Ala Glu Gly Ala Glu Arg Phe Ala Thr Leu Tyr 
        35                  40                  45              


Ser Thr Arg Asp Arg Ile Pro Val Tyr Ser Ala Phe Arg Ala Pro Arg 
    50                  55                  60                  


Pro Ala Pro Gly Gly Ala Glu Gln Arg Trp Leu Val Glu Pro Gln Ile 
65                  70                  75                  80  


Asp Asp Pro Asn Ser Asn Leu Glu Glu Ala Ile Asn Glu Ala Glu Ala 
                85                  90                  95      


Ile Thr Ser Val Asn Ser Leu Gly Ser Lys Gln Ala Leu Asn Thr Asp 
            100                 105                 110         


Tyr Leu Asp Ser Asp Tyr Gln Arg Gly Gln Leu Tyr Pro Phe Ser Leu 
        115                 120                 125             


Ser Ser Asp Val Gln Val Ala Thr Phe Thr Leu Thr Asn Ser Ala Pro 
    130                 135                 140                 


Met Thr Gln Ser Phe Gln Glu Arg Trp Tyr Val Asn Leu His Ser Leu 
145                 150                 155                 160 


Met Asp Arg Ala Leu Thr Pro Gln Cys Gly Ser Gly Glu Asp Leu Tyr 
                165                 170                 175     


Ile Leu Thr Gly Thr Val Pro Ser Asp Tyr Arg Val Lys Asp Lys Val 
            180                 185                 190         


Ala Val Pro Glu Phe Val Trp Leu Ala Ala Cys Cys Ala Val Pro Gly 
        195                 200                 205             


Gly Gly Trp Ala Met Gly Phe Val Lys His Thr Arg Asp Ser Asp Ile 
    210                 215                 220                 


Ile Glu Asp Val Met Val Lys Asp Leu Gln Lys Leu Leu Pro Phe Asn 
225                 230                 235                 240 


Pro Gln Leu Phe Gln Asn Asn Cys Gly Glu Thr Glu Gln Asp Thr Glu 
                245                 250                 255     


Lys Met Lys Lys Ile Leu Glu Val Val Asn Gln Ile Gln Asp Glu Glu 
            260                 265                 270         


Arg Met Val Gln Ser Gln Lys Ser Ser Ser Pro Leu Ser Ser Thr Arg 
        275                 280                 285             


Ser Lys Arg Ser Thr Leu Leu Pro Pro Glu Ala Ser Glu Gly Ser Ser 
    290                 295                 300                 


Ser Phe Leu Gly Lys Leu Met Gly Phe Ile Ala Thr Pro Phe Ile Lys 
305                 310                 315                 320 


Leu Phe Gln Leu Ile Tyr Tyr Leu Val Val Ala Ile Leu Lys Asn Ile 
                325                 330                 335     


Val Tyr Phe Leu Trp Cys Val Thr Lys Gln Val Ile Asn Gly Ile Glu 
            340                 345                 350         


Ser Cys Leu Tyr Arg Leu Gly Ser Ala Thr Ile Ser Tyr Phe Met Ala 
        355                 360                 365             


Ile Gly Glu Glu Leu Val Ser Ile Pro Trp Lys Val Leu Lys Val Val 
    370                 375                 380                 


Ala Lys Val Ile Arg Ala Leu Leu Arg Ile Leu Cys Cys Leu Leu Lys 
385                 390                 395                 400 


Ala Ile Cys Arg Val Leu Ser Ile Pro Val Arg Val Leu Val Asp Val 
                405                 410                 415     


Ala Thr Phe Pro Val Tyr Thr Met Gly Ala Ile Pro Ile Val Cys Lys 
            420                 425                 430         


Asp Ile Ala Leu Gly Leu Gly Gly Thr Val Ser Leu Leu Phe Asp Thr 
        435                 440                 445             


Ala Phe Gly Thr Leu Gly Gly Leu Phe Gln Val Val Phe Ser Val Cys 
    450                 455                 460                 


Lys Arg Ile Gly Tyr Lys Val Thr Phe Asp Asn Ser Gly Glu Leu 
465                 470                 475                 


<210>  1488
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  1488

Gly Lys Ile Glu Ser Cys Ala Ser Arg Cys Asn Glu Lys Phe Asn Arg 
1               5                   10                  15      


Asp Ala Ala Cys Gln Cys Asp Arg Arg Cys Leu Trp His Gly Asn Cys 
            20                  25                  30          


Cys Glu Asp Tyr Glu His Leu Cys Thr Glu Asp His Lys Glu Ser Glu 
        35                  40                  45              


Pro Leu Pro Gln Leu Glu Glu Glu Thr Glu Glu Ala Leu Ala Ser Asn 
    50                  55                  60                  


Leu Tyr Ser Ala Pro Thr Ser Cys Gln Gly Arg Cys Tyr Glu Ala Phe 
65                  70                  75                  80  


Asp Lys His His Gln Cys His Cys Asn Ala Arg Cys Gln Glu Phe Gly 
                85                  90                  95      


Asn Cys Cys Lys Asp Phe Glu Ser Leu Cys Ser Asp His Glu Val Ser 
            100                 105                 110         


His Ser Ser Asp Ala Ile Thr Lys Glu Glu Ile Gln Ser Ile Ser Glu 
        115                 120                 125             


Lys Ile Tyr Arg Ala Asp Thr Asn Lys Ala Gln Lys Glu Asp Ile Val 
    130                 135                 140                 


Leu Asn Ser Gln Asn Cys Ile Ser Pro Ser Glu Thr Arg Asn Gln Val 
145                 150                 155                 160 


Asp Arg Cys Pro Lys Pro Leu Phe Thr Tyr Val Asn Glu Lys Leu Phe 
                165                 170                 175     


Ser Lys Pro Thr Tyr Ala Ala Phe Ile Asn Leu Leu Asn Asn Tyr Gln 
            180                 185                 190         


Arg Ala Thr Gly His Gly Glu His Phe Ser Ala Gln Glu Leu Ala Glu 
        195                 200                 205             


Gln Asp Ala Phe Leu Arg Glu Ile Met Lys Thr Ala Val Met Lys Glu 
    210                 215                 220                 


Leu Tyr Ser Phe Leu His His Gln Asn Arg Tyr Gly Ser Glu Gln Glu 
225                 230                 235                 240 


Phe Val Asp Asp Leu Lys Asn Met Trp Phe Gly Leu Tyr Ser Arg Gly 
                245                 250                 255     


Asn Glu Glu Gly Asp Ser Ser Gly Phe Glu His Val Phe Ser Gly Glu 
            260                 265                 270         


Val Lys Lys Gly Lys Val Thr Gly Phe His Asn Trp Ile Arg Phe Tyr 
        275                 280                 285             


Leu Glu Glu Lys Glu Gly Leu Val Asp Tyr Tyr Ser His Ile Tyr Asp 
    290                 295                 300                 


Gly Pro Trp Asp Ser Tyr Pro Asp Val Leu Ala Met Gln Phe Asn Trp 
305                 310                 315                 320 


Asp Gly Tyr Tyr Lys Glu Val Gly Ser Ala Phe Ile Gly Ser Ser Pro 
                325                 330                 335     


Glu Phe Glu Phe Ala Leu Tyr Ser Leu Cys Phe Ile Ala Arg Pro Gly 
            340                 345                 350         


Lys Val Cys Gln Leu Ser Leu Gly Gly Tyr Pro Leu Ala Val Arg Thr 
        355                 360                 365             


Tyr Thr Trp Asp Lys Ser Thr Tyr Gly Asn Gly Lys Lys Tyr Ile Ala 
    370                 375                 380                 


Thr Ala Tyr Ile Val Ser Ser Thr 
385                 390         


<210>  1489
<211>  510
<212>  PRT
<213>  Homo Sapiens

<400>  1489

Gly Gln Asn Glu Ala Pro Pro Asn Thr His Ser Ile Pro Gly Glu Pro 
1               5                   10                  15      


Leu Tyr Asn Tyr Ala Ser Ile Arg Leu Pro Glu Glu His Ile Pro Phe 
            20                  25                  30          


Phe Leu His Asn Asn Arg His Ile Ala Thr Val Cys Arg Lys Asp Ser 
        35                  40                  45              


Leu Cys Pro Tyr Lys Lys His Leu Glu Lys Leu Lys Tyr Cys Trp Gly 
    50                  55                  60                  


Tyr Glu Lys Ser Cys Lys Pro Glu Phe Arg Phe Gly Tyr Pro Val Cys 
65                  70                  75                  80  


Ser Tyr Val Asp Met Gly Trp Thr Asp Thr Leu Glu Ser Ala Glu Asp 
                85                  90                  95      


Ile Phe Trp Lys Gln Ala Asp Phe Gly Tyr Ala Arg Glu Arg Leu Glu 
            100                 105                 110         


Glu Met His Val Leu Cys Gln Pro Lys Glu Thr Ser Asp Ser Ser Leu 
        115                 120                 125             


Val Cys Ser Arg Tyr Leu Gln Tyr Cys Arg Ala Thr Asn Leu Tyr Leu 
    130                 135                 140                 


Asp Leu Arg Asn Ile Lys Arg Asn His Asp Arg Phe Lys Glu Asp Phe 
145                 150                 155                 160 


Phe Gln Ser Gly Glu Ile Gly Gly His Cys Lys Leu Asp Ile Arg Thr 
                165                 170                 175     


Leu Thr Ser Glu Gly Gln Arg Lys Ser Pro Leu Gln Ser Trp Phe Ala 
            180                 185                 190         


Glu Leu Gln Ser Tyr Thr Gln Leu Asn Phe Arg Pro Ile Glu Asp Ala 
        195                 200                 205             


Lys Cys Asp Ile Val Ile Glu Lys Pro Thr Tyr Phe Met Lys Leu Asp 
    210                 215                 220                 


Ala Gly Val Asn Met Tyr His His Phe Cys Asp Phe Ile Asn Leu Tyr 
225                 230                 235                 240 


Ile Thr Gln His Val Asn Asn Ser Phe Ser Thr Asp Val Tyr Ile Val 
                245                 250                 255     


Met Trp Asp Thr Ser Ser Tyr Gly Tyr Gly Asp Leu Phe Ser Asp Thr 
            260                 265                 270         


Trp Asn Ala Phe Thr Asp Tyr Asp Val Ile His Leu Lys Thr Tyr Asp 
        275                 280                 285             


Ser Lys Arg Val Cys Phe Lys Glu Ala Val Phe Ser Leu Leu Pro Arg 
    290                 295                 300                 


Met Arg Tyr Gly Leu Phe Tyr Asn Thr Pro Leu Ile Ser Gly Cys Gln 
305                 310                 315                 320 


Asn Thr Gly Leu Phe Arg Ala Phe Ala Gln His Val Leu His Arg Leu 
                325                 330                 335     


Asn Ile Thr Gln Glu Gly Pro Lys Asp Gly Lys Ile Arg Val Thr Ile 
            340                 345                 350         


Leu Ala Arg Ser Thr Glu Tyr Arg Lys Ile Leu Asn Gln Asn Glu Leu 
        355                 360                 365             


Val Asn Ala Leu Lys Thr Val Ser Thr Phe Glu Val Gln Ile Val Asp 
    370                 375                 380                 


Tyr Lys Tyr Arg Glu Leu Gly Phe Leu Asp Gln Leu Arg Ile Thr His 
385                 390                 395                 400 


Asn Thr Asp Ile Phe Ile Gly Met His Gly Ala Gly Leu Thr His Leu 
                405                 410                 415     


Leu Phe Leu Pro Asp Trp Ala Ala Val Phe Glu Leu Tyr Asn Cys Glu 
            420                 425                 430         


Asp Glu Arg Cys Tyr Leu Asp Leu Ala Arg Leu Arg Gly Val His Tyr 
        435                 440                 445             


Ile Thr Trp Arg Arg Gln Asn Lys Val Phe Pro Gln Asp Lys Gly His 
    450                 455                 460                 


His Pro Thr Leu Gly Glu His Pro Lys Phe Thr Asn Tyr Ser Phe Asp 
465                 470                 475                 480 


Val Glu Glu Phe Met Tyr Leu Val Leu Gln Ala Ala Asp His Val Leu 
                485                 490                 495     


Gln His Pro Lys Trp Pro Phe Lys Lys Lys His Asp Glu Leu 
            500                 505                 510 


<210>  1490
<211>  361
<212>  PRT
<213>  Homo Sapiens

<400>  1490

Asn Ser Leu Leu Thr Glu Pro Pro Phe Arg Trp Arg Phe Tyr Leu His 
1               5                   10                  15      


Glu Thr Trp Thr Gln Gly Asn Arg Leu Ser Thr Val Thr Leu Ala Thr 
            20                  25                  30          


Val Asp Cys Gln Pro His Gly Cys Gln Ala Gln Val Thr Phe Asn Phe 
        35                  40                  45              


Thr Ser Phe Lys Ser Val Leu Arg Gly Trp Ser Asn Pro Thr Ile Cys 
    50                  55                  60                  


Phe Val Tyr Asp Gln Thr His Ser Asn Cys Arg Asp Tyr Trp Val Asp 
65                  70                  75                  80  


Thr Asn Gly Gly Cys Pro Tyr Ala Tyr Cys Arg Met His Val Thr Gln 
                85                  90                  95      


Leu His Thr Ala Lys Lys Leu Gln His Thr Tyr Arg Leu Thr Ser Asp 
            100                 105                 110         


Gly Arg Thr Thr Tyr Phe Leu Thr Ile Pro Asp Pro Trp Asp Ser Arg 
        115                 120                 125             


Trp Val Ser Gly Val Thr Gly Arg Leu Tyr Arg Trp Pro Thr Asp Ser 
    130                 135                 140                 


Tyr Pro Val Gly Lys Leu Arg Ile Phe Leu Thr Tyr Ile Arg Val Ile 
145                 150                 155                 160 


Pro Gln Val Leu Ser Asn Leu Lys Asp Gln Ala Asp Asn Ile Lys His 
                165                 170                 175     


Gln Glu Glu Val Ile Asn Thr Leu Val Gln Ser His Pro Lys Ala Asp 
            180                 185                 190         


Met Val Thr Tyr Asp Asp Lys Ala Glu Ala Gly Pro Phe Ser Trp Ile 
        195                 200                 205             


Thr Leu Val Arg His Gly Ala Arg Leu Val Asn Met Ala Gly Leu Val 
    210                 215                 220                 


Asn Leu Ser His Cys Phe Leu Cys Thr Ala Leu Ser Gln Pro Pro Leu 
225                 230                 235                 240 


Val Ala Val Pro Leu Pro Gln Ala Phe Asn Thr Ser Gly Asn His Thr 
                245                 250                 255     


Ala His Pro Ser Gly Val Phe Ser Glu Gln Val Pro Leu Phe Arg Asp 
            260                 265                 270         


Pro Leu Gln Pro Gln Phe Pro Phe Cys Tyr Thr Thr Pro Asn Ser Ser 
        275                 280                 285             


Trp Cys Asn Gln Thr Tyr Ser Gly Ser Leu Ser Asn Leu Ser Ala Pro 
    290                 295                 300                 


Ala Gly Gly Tyr Phe Trp Cys Asn Phe Thr Leu Thr Lys His Leu Asn 
305                 310                 315                 320 


Ile Ser Ser Asn Asn Thr Leu Ser Arg Asn Leu Cys Leu Pro Ile Ser 
                325                 330                 335     


Leu Val Pro Arg Leu Thr Leu Tyr Ser Glu Ala Glu Leu Ser Ser Leu 
            340                 345                 350         


Val Asn Pro Pro Met Arg Gln Lys Arg 
        355                 360     


<210>  1491
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1491

Ala Pro Pro Ser Cys Arg Glu Cys Tyr Gln Ser Leu His Tyr Arg Gly 
1               5                   10                  15      


Glu Met Gln Gln Tyr Phe Thr Tyr His Thr His Ile Glu Arg Ser Cys 
            20                  25                  30          


Tyr Gly Asn Leu Ile Glu Glu Cys Val Glu Ser Gly Lys Ser Tyr Tyr 
        35                  40                  45              


Lys Val Lys Asn Leu Gly Val Cys Gly Ser Arg Asn Gly Ala Ile Cys 
    50                  55                  60                  


Pro Arg Gly Lys Gln Trp Leu Cys Phe Thr Lys Ile Gly Gln Trp Gly 
65                  70                  75                  80  


Val Asn Thr Gln Val Leu Glu Asp Ile Lys Arg Glu Gln Ile Ile Ala 
                85                  90                  95      


Lys Ala Lys Ala Ser Lys Pro Thr Thr Pro Pro Glu Asn Arg Pro Arg 
            100                 105                 110         


His Phe His Ser Phe Ile Gln Lys Leu 
        115                 120     


<210>  1492
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  1492

Met Val Thr Pro Val Thr Trp Met Asp Asn Pro Ile Glu Val Tyr Val 
1               5                   10                  15      


Asn Asp Ser Val Trp Val Pro Gly Pro Thr Asp Asp Arg Cys Pro Ala 
            20                  25                  30          


Lys Pro Glu Glu Glu Gly Met Met Ile Asn Ile Ser Ile Gly Tyr His 
        35                  40                  45              


Tyr Pro Pro Ile Cys Leu Gly Arg Ala Pro Gly Cys Leu Met Pro Ala 
    50                  55                  60                  


Val Gln Asn Trp Leu Val Glu Val Pro Thr Val Ser Pro Asn Ser Arg 
65                  70                  75                  80  


Phe Thr Tyr His Met Val Ser Gly Met Ser Leu Arg Pro Arg Val Asn 
                85                  90                  95      


Cys Leu Gln Asp Phe Ser Tyr Gln Arg Ser Leu Lys Phe Arg Pro Lys 
            100                 105                 110         


Gly Lys Thr Cys Pro Lys Glu Ile Pro Lys Gly Ser Lys Asn Thr Glu 
        115                 120                 125             


Val Leu Val Trp Glu Glu Cys Val Ala Asn Ser Val Val Ile Leu Gln 
    130                 135                 140                 


Asn Asn Glu Phe Gly Thr Ile Ile Asp Trp Ala Pro Arg Gly Gln Phe 
145                 150                 155                 160 


Tyr His Asn Cys Ser Gly Gln Thr Gln Ser Cys Pro Ser Ala Gln Val 
                165                 170                 175     


Ser Pro Ala Val Asp Ser Asp Leu Thr Glu Ser Leu Asp Lys His Lys 
            180                 185                 190         


His Lys Lys Leu Gln Ser Phe Tyr Leu Trp Glu Trp Glu Glu Lys Gly 
        195                 200                 205             


Ile Ser Thr Pro Arg Pro Lys Ile Ile Ser Pro Val Ser Gly Pro Glu 
    210                 215                 220                 


His Pro Glu Leu Trp Arg Leu Thr Val Ala Ser His His Ile Arg Ile 
225                 230                 235                 240 


Trp Ser Gly Asn Gln Thr Leu Glu Thr Arg Tyr Arg Lys Pro Phe Tyr 
                245                 250                 255     


Thr Ile Asp Leu Asn Ser Ile Leu Thr Val Pro Leu Gln Ser Cys Val 
            260                 265                 270         


Lys Pro Pro Tyr Met Leu Val Val Gly Asn Ile Val Ile Lys Pro Ala 
        275                 280                 285             


Ser Gln Thr Ile Thr Cys Glu Asn Cys Arg Leu Phe Thr Cys Ile Asp 
    290                 295                 300                 


Ser Thr Phe Asn Trp Gln His Arg Ile Leu Leu Val Arg Ala Arg Glu 
305                 310                 315                 320 


Gly Met Trp Ile Pro Val Ser Thr Asp Arg Pro Trp Glu Ala Ser Pro 
                325                 330                 335     


Ser Ile His Ile Leu Thr Glu Ile Leu Lys Gly Val Leu Asn Arg Ser 
            340                 345                 350         


Lys Arg 
        


<210>  1493
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  1493

Met Val Thr Pro Val Thr Trp Met Asp Asn Pro Ile Glu Val Tyr Val 
1               5                   10                  15      


Asn Asp Ser Glu Trp Val Pro Gly Pro Thr Asp Asp Arg Cys Pro Ala 
            20                  25                  30          


Lys Pro Glu Glu Glu Gly Met Met Ile Asn Ile Ser Ile Gly Tyr Arg 
        35                  40                  45              


Tyr Pro Pro Ile Cys Leu Gly Thr Ala Pro Gly Cys Leu Met Pro Ala 
    50                  55                  60                  


Val Gln Asn Trp Leu Val Glu Val Pro Ile Val Ser Pro Ile Ser Arg 
65                  70                  75                  80  


Phe Thr Tyr His Met Val Ser Gly Met Ser Leu Arg Pro Arg Val Asn 
                85                  90                  95      


Tyr Leu Gln Asp Phe Pro Tyr Gln Arg Ser Leu Lys Phe Arg Pro Lys 
            100                 105                 110         


Gly Lys Pro Cys Pro Lys Glu Ile Pro Lys Glu Ser Lys Asn Thr Glu 
        115                 120                 125             


Val Leu Val Trp Glu Glu Cys Val Ala Asn Ser Ala Val Ile Leu Gln 
    130                 135                 140                 


Asn Asn Glu Phe Gly Thr Ile Ile Asp Trp Ala Pro Arg Gly Gln Phe 
145                 150                 155                 160 


Tyr His Asn Cys Ser Gly Gln Thr Gln Ser Cys Pro Ser Ala Gln Val 
                165                 170                 175     


Ser Pro Ala Val Asp Ser Asp Leu Thr Glu Ser Leu Asp Lys His Lys 
            180                 185                 190         


His Lys Lys Leu Gln Ser Phe Tyr Pro Trp Glu Trp Gly Glu Lys Gly 
        195                 200                 205             


Ile Ser Thr Pro Arg Pro Lys Ile Ile Ser Pro Val Ser Gly Pro Glu 
    210                 215                 220                 


His Pro Glu Leu Trp Arg Leu Thr Val Ala Ser His His Ile Arg Ile 
225                 230                 235                 240 


Trp Ser Gly Asn Gln Thr Leu Glu Thr Arg Asp Arg Lys Pro Phe Tyr 
                245                 250                 255     


Thr Val Asp Leu Asn Ser Ser Leu Thr Leu Pro Leu Gln Ser Cys Val 
            260                 265                 270         


Lys Pro Pro Tyr Met Leu Val Val Gly Asn Ile Val Ile Lys Pro Asp 
        275                 280                 285             


Ser Gln Thr Ile Thr Cys Glu Asn Cys Arg Leu Leu Thr Cys Ile Asp 
    290                 295                 300                 


Ser Thr Phe Asn Trp Gln His Arg Ile Leu Leu Val Arg Ala Arg Glu 
305                 310                 315                 320 


Gly Val Trp Ile Leu Val Ser Met Asp Arg Pro Trp Glu Ala Ser Pro 
                325                 330                 335     


Ser Val His Ile Leu Thr Glu Val Leu Lys Gly Val Leu Asn Arg Ser 
            340                 345                 350         


Lys Arg 
        


<210>  1494
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  1494

Met Val Thr Pro Val Thr Trp Met Asp Asn Pro Ile Glu Ile Tyr Val 
1               5                   10                  15      


Asn Asp Ser Val Trp Val Pro Gly Pro Ile Asp Asp Arg Cys Pro Ala 
            20                  25                  30          


Lys Pro Glu Glu Glu Gly Met Met Ile Asn Ile Ser Ile Gly Tyr Arg 
        35                  40                  45              


Tyr Pro Pro Ile Cys Leu Gly Arg Ala Pro Gly Cys Leu Met Pro Ala 
    50                  55                  60                  


Val Gln Asn Trp Leu Val Glu Val Pro Thr Val Ser Pro Ile Ser Arg 
65                  70                  75                  80  


Phe Thr Tyr His Met Val Ser Gly Met Ser Leu Arg Pro Arg Val Asn 
                85                  90                  95      


Tyr Leu Gln Asp Phe Ser Tyr Gln Arg Ser Leu Lys Phe Arg Pro Lys 
            100                 105                 110         


Gly Lys Pro Cys Pro Lys Glu Ile Pro Lys Glu Ser Lys Asn Thr Glu 
        115                 120                 125             


Val Leu Val Trp Glu Glu Cys Val Ala Asn Ser Ala Val Ile Leu Gln 
    130                 135                 140                 


Asn Asn Glu Phe Gly Thr Ile Ile Asp Trp Ala Pro Arg Gly Gln Phe 
145                 150                 155                 160 


Tyr His Asn Cys Ser Gly Gln Thr Gln Ser Cys Pro Ser Ala Gln Val 
                165                 170                 175     


Ser Pro Ala Val Asp Ser Asp Leu Thr Glu Ser Leu Asp Lys His Lys 
            180                 185                 190         


His Lys Lys Leu Gln Ser Phe Tyr Pro Trp Glu Trp Gly Glu Lys Arg 
        195                 200                 205             


Ile Ser Thr Pro Arg Pro Lys Ile Val Ser Pro Val Ser Gly Pro Glu 
    210                 215                 220                 


His Pro Glu Leu Trp Arg Leu Thr Val Ala Ser His His Ile Arg Ile 
225                 230                 235                 240 


Trp Ser Gly Asn Gln Thr Leu Glu Thr Arg Asp Cys Lys Pro Phe Tyr 
                245                 250                 255     


Thr Ile Asp Leu Asn Ser Ser Leu Thr Val Pro Leu Gln Ser Cys Val 
            260                 265                 270         


Lys Pro Pro Tyr Met Leu Val Val Gly Asn Ile Val Ile Lys Pro Asp 
        275                 280                 285             


Ser Gln Thr Ile Thr Cys Glu Asn Cys Arg Leu Leu Ser Cys Ile Asp 
    290                 295                 300                 


Ser Thr Phe Asn Trp Gln His Arg Ile Leu Leu Val Arg Ala Arg Glu 
305                 310                 315                 320 


Gly Val Trp Ile Pro Val Ser Met Asp Arg Pro Trp Glu Ala Ser Pro 
                325                 330                 335     


Ser Val His Ile Leu Thr Glu Val Leu Lys Gly Val Leu Asn Arg Ser 
            340                 345                 350         


Lys Arg 
        


<210>  1495
<211>  289
<212>  PRT
<213>  Homo Sapiens

<400>  1495

Met Trp Thr Val Pro Ser Phe Thr Asn Asp Ser Tyr Gln Val Tyr Asn 
1               5                   10                  15      


Val Phe Ser Thr Asn Ser Phe Gln Leu Leu Thr Val Lys Arg Thr Pro 
            20                  25                  30          


His Glu Ala Trp Arg Val Pro Leu Thr Thr Lys Thr Asn Lys Thr Lys 
        35                  40                  45              


Gly Leu Pro Asp Cys Pro Lys Lys Pro Thr Asn Gly Pro Phe Ile Val 
    50                  55                  60                  


Thr Ser Ile Leu Trp Asp Asn Cys Asn Ala Pro Lys Ala Val Val Leu 
65                  70                  75                  80  


Gln Thr Leu Ala Met Gly Ile Val Ile Asp Trp Ala Pro Lys Gly His 
                85                  90                  95      


Tyr Trp Gln Asp Cys Ser Ser Lys Asn Thr Leu Cys Ser Glu Phe Ile 
            100                 105                 110         


Tyr Ser Leu Asp Tyr Ile Glu His Gly Trp Gln Ser Tyr Thr Met Arg 
        115                 120                 125             


Gln Arg Val Ser Pro Tyr Pro Phe Lys Trp Met Asp Thr Gly Ile Ala 
    130                 135                 140                 


Pro Pro Arg Pro Lys Ile Ile His Pro Phe Phe Thr Pro Glu His Pro 
145                 150                 155                 160 


Glu Leu Trp Lys Leu Ala Ala Ala Leu Ser Gly Ile Lys Ile Trp Asn 
                165                 170                 175     


Thr Thr Tyr Gln Leu Leu Arg Thr Lys Thr Lys Thr Pro Thr Phe Asn 
            180                 185                 190         


Ile Thr Leu Ile Ser Glu Trp Val Ile Pro Ile Arg Ser Cys Val Lys 
        195                 200                 205             


Pro Pro Tyr Met Leu Leu Val Gly Asn Ile Ile Met Met Pro Asp Ala 
    210                 215                 220                 


Gln Thr Ile Glu Cys His Asn Cys Lys Leu Phe Thr Cys Ile Asp Ala 
225                 230                 235                 240 


Thr Phe Asn Pro Thr Thr Ser Ile Leu Leu Val Arg Ala Arg Glu Gly 
                245                 250                 255     


Val Trp Ile Pro Val Ser Leu His Arg Pro Trp Glu Ser Ser Pro Ser 
            260                 265                 270         


Ile His Ile Val Asn Glu Val Leu Lys Asp Ile Leu Lys Arg Thr Lys 
        275                 280                 285             


Arg 
    


<210>  1496
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  1496

Gln Trp Asn Glu Asn Ser Leu Val Ser Phe Ser Lys Ile Ile Ala Ser 
1               5                   10                  15      


Gly Asn His Leu Ser Asn Cys Trp Ile Cys His Asn Phe Ile Thr Arg 
            20                  25                  30          


Ser Ser Ser Tyr Gln Tyr Ile Leu Val Arg Asn Phe Ser Leu Asn Leu 
        35                  40                  45              


Thr Phe Gly Ser Gly Ile Pro Glu Gly Gln His Lys Ser Val Pro Leu 
    50                  55                  60                  


Gln Val Ser Leu Ala Asn Ser Ala His Gln Val Pro Cys Leu Asp Leu 
65                  70                  75                  80  


Thr Pro Pro Phe Asn Gln Ser Ser Lys Thr Ser Phe Tyr Phe Tyr Asn 
                85                  90                  95      


Cys Ser Ser Leu Asn Gln Thr Cys Cys Pro Cys Pro Glu Gly His Cys 
            100                 105                 110         


Asp Arg Lys Asn Thr Ser Glu Glu Gly Phe Pro Ser Pro Thr Ile His 
        115                 120                 125             


Pro Met Ser Phe Ser Pro Ala Gly Cys His Pro Asn Leu Thr His Trp 
    130                 135                 140                 


Cys Pro Ala Lys Gln Met Asn Asp Tyr Arg Asp Lys Ser Pro Gln Asn 
145                 150                 155                 160 


Arg Cys Ala Ala Trp Glu Gly Lys Glu Leu Ile Thr Trp Arg Val Leu 
                165                 170                 175     


Tyr Leu Leu Pro Lys Ala His Thr Val Pro Thr Trp Pro Lys Ser Thr 
            180                 185                 190         


Val Pro Leu Gly Gly Pro Leu Ser Pro Ala Cys Asn Gln Thr Ile Pro 
        195                 200                 205             


Ala Gly Trp Lys Ser Gln Leu His Lys Trp Phe Asp Ser His Ile Pro 
    210                 215                 220                 


Arg Trp Ala Cys Thr Pro Pro Gly Tyr Val Phe Leu Cys Gly Pro Gln 
225                 230                 235                 240 


Lys Asn Lys Leu Pro Phe Asp Gly Ser Pro Lys Ile Thr Tyr Ser Thr 
                245                 250                 255     


Pro Pro Val Ala Asn Leu Tyr Thr Cys Ile Asn Asn Ile Gln His Thr 
            260                 265                 270         


Gly Glu Cys Ala Val Gly Leu Leu Gly Pro Arg Gly Ile Gly Val Thr 
        275                 280                 285             


Ile Tyr Asn Thr Thr Gln Pro Arg Gln Lys Arg Ala 
    290                 295                 300 


<210>  1497
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  1497

Gln Trp Asn Glu Asn Ser Leu Val Ser Phe Ser Lys Ile Ile Ala Ser 
1               5                   10                  15      


Gly Asn His Leu Ser Asn Cys Trp Ile Cys His Asn Phe Ile Thr Arg 
            20                  25                  30          


Ser Ser Ser Tyr Gln Tyr Ile Leu Val Arg Asn Phe Ser Leu Asn Leu 
        35                  40                  45              


Thr Phe Gly Ser Gly Ile Pro Glu Gly Gln His Lys Ser Val Pro Leu 
    50                  55                  60                  


Gln Val Ser Leu Ala Asn Ser Ala His Gln Val Pro Cys Leu Asp Leu 
65                  70                  75                  80  


Thr Pro Pro Phe Asn Gln Ser Ser Lys Thr Ser Phe Tyr Phe Tyr Asn 
                85                  90                  95      


Cys Ser Ser Leu Asn Gln Thr Cys Cys Pro Cys Pro Glu Gly His Cys 
            100                 105                 110         


Asp Arg Lys Asn Thr Ser Glu Glu Gly Phe Pro Ser Pro Thr Ile His 
        115                 120                 125             


Pro Met Ser Phe Ser Pro Ala Gly Cys His Pro Asn Leu Thr His Trp 
    130                 135                 140                 


Cys Pro Ala Lys Gln Met Asn Asp Tyr Arg Asp Lys Ser Pro Gln Asn 
145                 150                 155                 160 


Arg Cys Ala Ala Trp Glu Gly Lys Glu Leu Ile Thr Trp Arg Val Leu 
                165                 170                 175     


Tyr Ser Leu Pro Lys Ala His Thr Val Pro Thr Trp Pro Lys Ser Thr 
            180                 185                 190         


Val Pro Leu Gly Gly Pro Leu Ser Pro Ala Cys Asn Gln Thr Ile Pro 
        195                 200                 205             


Ala Gly Trp Lys Ser Gln Leu His Lys Trp Phe Asp Ser His Ile Pro 
    210                 215                 220                 


Arg Trp Ala Cys Thr Pro Pro Gly Tyr Val Phe Leu Cys Gly Pro Gln 
225                 230                 235                 240 


Lys Asn Lys Leu Pro Phe Asp Gly Ser Pro Lys Ile Thr Tyr Ser Thr 
                245                 250                 255     


Pro Pro Val Ala Asn Leu Tyr Thr Cys Ile Asn Asn Ile Gln His Thr 
            260                 265                 270         


Gly Glu Cys Ala Val Gly Leu Leu Gly Pro Arg Gly Ile Gly Val Thr 
        275                 280                 285             


Ile Tyr Asn Thr Thr Gln Pro Arg Gln Lys Arg Ala 
    290                 295                 300 


<210>  1498
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  1498

Asn Tyr Thr Arg Leu Trp Ala Asn Ser Thr Ser Ser Trp Asp Ser Val 
1               5                   10                  15      


Ile Gln Asn Lys Thr Gly Arg Asn Gln Asn Glu Asn Ile Asn Thr Asn 
            20                  25                  30          


Pro Ile Thr Pro Glu Val Asp Tyr Lys Gly Asn Ser Thr Asn Met Pro 
        35                  40                  45              


Glu Thr Ser His Ile Val Ala Leu Thr Ser Lys Ser Glu Gln Glu Leu 
    50                  55                  60                  


Tyr Ile Pro Ser Val Val Ser Asn Ser Pro Ser Thr Val Gln Ser Ile 
65                  70                  75                  80  


Glu Asn Thr Ser Lys Ser His Gly Glu Ile Phe Lys Lys Asp Val Cys 
                85                  90                  95      


Ala Glu Asn Asn Asn Asn Met 
            100             


<210>  1499
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  1499

Val Pro Arg Phe Pro Arg Thr Glu Val Gly Ala Gly His Ser Val Asn 
1               5                   10                  15      


Glu Glu Thr Lys Ala Glu Lys Val Gly Asn Gln Thr Ser Val Ile Pro 
            20                  25                  30          


Ala Thr Ser Arg Gln Ala Ala Leu Gly Thr Ser Trp Thr Gln Arg Arg 
        35                  40                  45              


Thr Gln Pro Leu Gln Glu Arg Ser His Trp His Pro Arg Gly Asn Asn 
    50                  55                  60                  


Ala Ser Gly Met Gly Gly His Arg Met Phe Pro Gly Pro Leu Arg Gly 
65                  70                  75                  80  


Pro Ala Ala Gln Val Leu Glu Asn Glu Cys Gly Ser Leu Gly Arg Ala 
                85                  90                  95      


Ala Glu Gly Arg Ser 
            100     


<210>  1500
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  1500

Pro Gly Ala Asn Pro Thr Phe Gln Thr Gly Tyr Thr Pro Gly Thr Pro 
1               5                   10                  15      


Tyr Lys Val Ser Cys Ser Pro Thr Ser Gly Ala Val Pro Pro Tyr Ser 
            20                  25                  30          


Ser Ser Pro Asn Pro Tyr Gln Thr Ala Val Tyr Pro Val Arg Ser Ala 
        35                  40                  45              


Tyr Pro Gln Gln Ser Pro Tyr Ala Gln Gln Gly Thr Tyr Tyr Thr Gln 
    50                  55                  60                  


Pro Leu Tyr Ala Ala Pro Pro His Val Ile His His Thr Thr Val Val 
65                  70                  75                  80  


Gln Pro Asn Gly Met Pro Ala Thr Val Tyr Pro Ala Pro Ile Pro Pro 
                85                  90                  95      


Pro Arg Gly Asn 
            100 


<210>  1501
<211>  89
<212>  PRT
<213>  Homo Sapiens

<400>  1501

Thr Cys Glu Ile Val Thr Leu Asp Arg Asp Ser Ser Gln Pro Arg Arg 
1               5                   10                  15      


Thr Ile Ala Arg Gln Thr Ala Arg Cys Ala Cys Arg Lys Gly Gln Ile 
            20                  25                  30          


Ala Gly Thr Thr Arg Ala Arg Pro Ala Cys Val Asp Ala Arg Ile Ile 
        35                  40                  45              


Lys Thr Lys Gln Trp Cys Asp Met Leu Pro Cys Leu Glu Gly Glu Gly 
    50                  55                  60                  


Cys Asp Leu Leu Ile Asn Arg Ser Gly Trp Thr Cys Thr Gln Pro Gly 
65                  70                  75                  80  


Gly Arg Ile Lys Thr Thr Thr Val Ser 
                85                  


<210>  1502
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  1502

Leu Tyr Phe Lys Val Ala Lys Ala Leu Lys Ala Ala Lys Asp Pro Asp 
1               5                   10                  15      


Ala Val Ala Val Lys Asn His Asn Pro Asp Lys Val Cys Trp Ala Thr 
            20                  25                  30          


Asn Ser Gln Ala Lys Ala Thr Thr Met Glu Ser Cys Pro Ser Leu Gln 
        35                  40                  45              


Cys Cys Glu Gly Cys Arg Met His Ala Ser Ser Asp Ser Leu Pro Pro 
    50                  55                  60                  


Cys Cys Cys Asp Ile Asn Glu Gly Leu 
65                  70              


<210>  1503
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  1503

Phe Pro Arg Ile Gln Gln Leu Phe Thr Ser Pro Glu Ser Ser Val Thr 
1               5                   10                  15      


Ala Ala Pro Arg Ala Arg Lys Tyr Lys Cys Gly Leu Pro Gln Pro Cys 
            20                  25                  30          


Pro Glu Glu His Leu Ala Phe Arg Val Val Ser Gly Ala Ala Asn Val 
        35                  40                  45              


Ile Gly Pro Lys Ile Cys Leu Glu Asp Lys Met Leu Met Ser Ser Val 
    50                  55                  60                  


Lys Asp Asn Val Gly Arg Gly Leu Asn Ile Ala Leu Val Asn Gly Val 
65                  70                  75                  80  


Ser Gly Glu Leu Ile Glu Ala Arg Ala Phe Asp Met Trp Ala Gly Asp 
                85                  90                  95      


Val Asn Asp Leu Leu Lys Phe Ile Arg Pro Leu His Glu Gly Thr Leu 
            100                 105                 110         


Val Phe Val Ala Ser Tyr Asp Asp Pro Ala Thr Lys Met Asn Glu Glu 
        115                 120                 125             


Thr Arg Lys Leu Phe Ser Glu Leu Gly Ser Arg Asn Ala Lys Glu Leu 
    130                 135                 140                 


Ala Phe Arg Asp Ser Trp Val Phe Val Gly Ala Lys Gly Val Gln Asn 
145                 150                 155                 160 


Lys Ser Pro Phe Glu Gln His Val Lys Asn Ser Lys His Ser Asn Lys 
                165                 170                 175     


Tyr Glu Gly Trp Pro Glu Ala Leu Glu Met Glu Gly Cys Ile Pro Arg 
            180                 185                 190         


Arg Ser Thr Ala Ser 
        195         


<210>  1504
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  1504

Leu Gln Ala Ala Asp Thr Cys Pro Glu Val Lys Met Val Gly Leu Glu 
1               5                   10                  15      


Gly Ser Asp Lys Leu Thr Ile Leu Arg Gly Cys Pro Gly Leu Pro Gly 
            20                  25                  30          


Ala Pro Gly Pro Lys Gly Glu Ala Gly Thr Asn Gly Lys Arg Gly Glu 
        35                  40                  45              


Arg Gly Pro Pro Gly Pro Pro Gly Lys Ala Gly Pro Pro Gly Pro Asn 
    50                  55                  60                  


Gly Ala Pro Gly Glu Pro Gln Pro Cys Leu Thr Gly Pro Arg Thr Cys 
65                  70                  75                  80  


Lys Asp Leu Leu Asp Arg Gly His Phe Leu Ser Gly Trp His Thr Ile 
                85                  90                  95      


Tyr Leu Pro Asp Cys Arg Pro Leu Thr Val Leu Cys Asp Met Asp Thr 
            100                 105                 110         


Asp Gly Gly Gly Trp Thr Val Phe Gln Arg Arg Val Asp Gly Ser Val 
        115                 120                 125             


Asp Phe Tyr Arg Asp Trp Ala Thr Tyr Lys Gln Gly Phe Gly Ser Arg 
    130                 135                 140                 


Leu Gly Glu Phe Trp Leu Gly Asn Asp Asn Ile His Ala Leu Thr Ala 
145                 150                 155                 160 


Gln Gly Thr Ser Glu Leu Arg Val Asp Leu Val Asp Phe Glu Asp Asn 
                165                 170                 175     


Tyr Gln Phe Ala Lys Tyr Arg Ser Phe Lys Val Ala Asp Glu Ala Glu 
            180                 185                 190         


Lys Tyr Asn Leu Val Leu Gly Ala Phe Val Glu Gly Ser Ala Gly Asp 
        195                 200                 205             


Ser Leu Thr Phe His Asn Asn Gln Ser Phe Ser Thr Lys Asp Gln Asp 
    210                 215                 220                 


Asn Asp Leu Asn Thr Gly Asn Cys Ala Val Met Phe Gln Gly Ala Trp 
225                 230                 235                 240 


Trp Tyr Lys Asn Cys His Val Ser Asn Leu Asn Gly Arg Tyr Leu Arg 
                245                 250                 255     


Gly Thr His Gly Ser Phe Ala Asn Gly Ile Asn Trp Lys Ser Gly Lys 
            260                 265                 270         


Gly Tyr Asn Tyr Ser Tyr Lys Val Ser Glu Met Lys Val Arg Pro Ala 
        275                 280                 285             


<210>  1505
<211>  367
<212>  PRT
<213>  Homo Sapiens

<400>  1505

Cys Gly Ala Met Ser Pro Pro Gln Leu Ala Leu Asn Pro Ser Ala Leu 
1               5                   10                  15      


Leu Ser Arg Gly Cys Asn Asp Ser Asp Val Leu Ala Val Ala Gly Phe 
            20                  25                  30          


Ala Leu Arg Asp Ile Asn Lys Asp Arg Lys Asp Gly Tyr Val Leu Arg 
        35                  40                  45              


Leu Asn Arg Val Asn Asp Ala Gln Glu Tyr Arg Arg Gly Gly Leu Gly 
    50                  55                  60                  


Ser Leu Phe Tyr Leu Thr Leu Asp Val Leu Glu Thr Asp Cys His Val 
65                  70                  75                  80  


Leu Arg Lys Lys Ala Trp Gln Asp Cys Gly Met Arg Ile Phe Phe Glu 
                85                  90                  95      


Ser Val Tyr Gly Gln Cys Lys Ala Ile Phe Tyr Met Asn Asn Pro Ser 
            100                 105                 110         


Arg Val Leu Tyr Leu Ala Ala Tyr Asn Cys Thr Leu Arg Pro Val Ser 
        115                 120                 125             


Lys Lys Lys Ile Tyr Met Thr Cys Pro Asp Cys Pro Ser Ser Ile Pro 
    130                 135                 140                 


Thr Asp Ser Ser Asn His Gln Val Leu Glu Ala Ala Thr Glu Ser Leu 
145                 150                 155                 160 


Ala Lys Tyr Asn Asn Glu Asn Thr Ser Lys Gln Tyr Ser Leu Phe Lys 
                165                 170                 175     


Val Thr Arg Ala Ser Ser Gln Trp Val Val Gly Pro Ser Tyr Phe Val 
            180                 185                 190         


Glu Tyr Leu Ile Lys Glu Ser Pro Cys Thr Lys Ser Gln Ala Ser Ser 
        195                 200                 205             


Cys Ser Leu Gln Ser Ser Asp Ser Val Pro Val Gly Leu Cys Lys Gly 
    210                 215                 220                 


Ser Leu Thr Arg Thr His Trp Glu Lys Phe Val Ser Val Thr Cys Asp 
225                 230                 235                 240 


Phe Phe Glu Ser Gln Ala Pro Ala Thr Gly Ser Glu Asn Ser Ala Val 
                245                 250                 255     


Asn Gln Lys Pro Thr Asn Leu Pro Lys Val Glu Glu Ser Gln Gln Lys 
            260                 265                 270         


Asn Thr Pro Pro Thr Asp Ser Pro Ser Lys Ala Gly Pro Arg Gly Ser 
        275                 280                 285             


Val Gln Tyr Leu Pro Asp Leu Asp Asp Lys Asn Ser Gln Glu Lys Gly 
    290                 295                 300                 


Pro Gln Glu Ala Phe Pro Val His Leu Asp Leu Thr Thr Asn Pro Gln 
305                 310                 315                 320 


Gly Glu Thr Leu Asp Ile Ser Phe Leu Phe Leu Glu Pro Met Glu Glu 
                325                 330                 335     


Lys Leu Val Val Leu Pro Phe Pro Lys Glu Lys Ala Arg Thr Ala Glu 
            340                 345                 350         


Cys Pro Gly Pro Ala Gln Asn Ala Ser Pro Leu Val Leu Pro Pro 
        355                 360                 365         


<210>  1506
<211>  148
<212>  PRT
<213>  Homo Sapiens

<400>  1506

Thr Pro Ser Ala Ser Arg Gly Pro Arg Ser Tyr Pro His Leu Glu Gly 
1               5                   10                  15      


Asp Val Arg Trp Arg Arg Leu Phe Ser Ser Thr His Phe Phe Leu Arg 
            20                  25                  30          


Val Asp Pro Gly Gly Arg Val Gln Gly Thr Arg Trp Arg His Gly Gln 
        35                  40                  45              


Asp Ser Ile Leu Glu Ile Arg Ser Val His Val Gly Val Val Val Ile 
    50                  55                  60                  


Lys Ala Val Ser Ser Gly Phe Tyr Val Ala Met Asn Arg Arg Gly Arg 
65                  70                  75                  80  


Leu Tyr Gly Ser Arg Leu Tyr Thr Val Asp Cys Arg Phe Arg Glu Arg 
                85                  90                  95      


Ile Glu Glu Asn Gly His Asn Thr Tyr Ala Ser Gln Arg Trp Arg Arg 
            100                 105                 110         


Arg Gly Gln Pro Met Phe Leu Ala Leu Asp Arg Arg Gly Gly Pro Arg 
        115                 120                 125             


Pro Gly Gly Arg Thr Arg Arg Tyr His Leu Ser Ala His Phe Leu Pro 
    130                 135                 140                 


Val Leu Val Ser 
145             


<210>  1507
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  1507

Ala Pro Thr Ala Pro Asn Gly Thr Leu Glu Ala Glu Leu Glu Arg Arg 
1               5                   10                  15      


Trp Glu Ser Leu Val Ala Leu Ser Leu Ala Arg Leu Pro Val Ala Ala 
            20                  25                  30          


Gln Pro Lys Glu Ala Ala Val Gln Ser Gly Ala Gly Asp Tyr Leu Leu 
        35                  40                  45              


Gly Ile Lys Arg Leu Arg Arg Leu Tyr Cys Asn Val Gly Ile Gly Phe 
    50                  55                  60                  


His Leu Gln Ala Leu Pro Asp Gly Arg Ile Gly Gly Ala His Ala Asp 
65                  70                  75                  80  


Thr Arg Asp Ser Leu Leu Glu Leu Ser Pro Val Glu Arg Gly Val Val 
                85                  90                  95      


Ser Ile Phe Gly Val Ala Ser Arg Phe Phe Val Ala Met Ser Ser Lys 
            100                 105                 110         


Gly Lys Leu Tyr Gly Ser Pro Phe Phe Thr Asp Glu Cys Thr Phe Lys 
        115                 120                 125             


Glu Ile Leu Leu Pro Asn Asn Tyr Asn Ala Tyr Glu Ser Tyr Lys Tyr 
    130                 135                 140                 


Pro Gly Met Phe Ile Ala Leu Ser Lys Asn Gly Lys Thr Lys Lys Gly 
145                 150                 155                 160 


Asn Arg Val Ser Pro Thr Met Lys Val Thr His Phe Leu Pro Arg Leu 
                165                 170                 175     


<210>  1508
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  1508

Gln Glu Gly Pro Gly Arg Gly Pro Ala Leu Gly Arg Glu Leu Ala Ser 
1               5                   10                  15      


Leu Phe Arg Ala Gly Arg Glu Pro Gln Gly Val Ser Gln Gln His Val 
            20                  25                  30          


Arg Glu Gln Ser Leu Val Thr Asp Gln Leu Ser Arg Arg Leu Ile Arg 
        35                  40                  45              


Thr Tyr Gln Leu Tyr Ser Arg Thr Ser Gly Lys His Val Gln Val Leu 
    50                  55                  60                  


Ala Asn Lys Arg Ile Asn Ala Met Ala Glu Asp Gly Asp Pro Phe Ala 
65                  70                  75                  80  


Lys Leu Ile Val Glu Thr Asp Thr Phe Gly Ser Arg Val Arg Val Arg 
                85                  90                  95      


Gly Ala Glu Thr Gly Leu Tyr Ile Cys Met Asn Lys Lys Gly Lys Leu 
            100                 105                 110         


Ile Ala Lys Ser Asn Gly Lys Gly Lys Asp Cys Val Phe Thr Glu Ile 
        115                 120                 125             


Val Leu Glu Asn Asn Tyr Thr Ala Leu Gln Asn Ala Lys Tyr Glu Gly 
    130                 135                 140                 


Trp Tyr Met Ala Phe Thr Arg Lys Gly Arg Pro Arg Lys Gly Ser Lys 
145                 150                 155                 160 


Thr Arg Gln His Gln Arg Glu Val His Phe Met Lys Arg Leu Pro Arg 
                165                 170                 175     


Gly His His Thr Thr Glu Gln Ser Leu Arg Phe Glu Phe Leu Asn Tyr 
            180                 185                 190         


Pro Pro Phe Thr Arg Ser Leu Arg Gly Ser Gln Arg Thr Trp Ala Pro 
        195                 200                 205             


Glu Pro Arg 
    210     


<210>  1509
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  1509

Arg Arg Val Ala Val Thr Ala Arg His Leu Ser Arg Leu Val Val Gly 
1               5                   10                  15      


Ala Ala Val Trp Arg Gly Ala Gly Arg Ala Phe Leu Leu Ile Glu Asp 
            20                  25                  30          


Leu Thr Gly Ser Cys Phe Glu Pro Leu Pro Gln Gly Leu Leu Leu His 
        35                  40                  45              


Glu Leu Pro Asp Arg Arg Ser Cys Leu Ala Ala Gly His Gln Trp Arg 
    50                  55                  60                  


Gly Tyr Thr Val Ser Ser His Thr 
65                  70          


<210>  1510
<211>  413
<212>  PRT
<213>  Homo Sapiens

<400>  1510

Leu Trp Gly Gly Leu Leu Pro Pro Arg Thr Glu Leu Pro Ala Ser Arg 
1               5                   10                  15      


Pro Pro Glu Asp Arg Leu Pro Arg Arg Pro Ala Arg Ser Gly Gly Pro 
            20                  25                  30          


Ala Pro Ala Pro Arg Phe Pro Leu Pro Pro Pro Leu Ala Trp Asp Ala 
        35                  40                  45              


Arg Gly Gly Ser Leu Lys Thr Phe Arg Ala Leu Leu Thr Leu Ala Ala 
    50                  55                  60                  


Gly Ala Asp Gly Pro Pro Arg Gln Ser Arg Ser Glu Pro Arg Trp His 
65                  70                  75                  80  


Val Ser Ala Arg Gln Pro Arg Pro Glu Glu Ser Ala Ala Val His Gly 
                85                  90                  95      


Gly Val Phe Trp Ser Arg Gly Leu Glu Glu Gln Val Pro Pro Gly Phe 
            100                 105                 110         


Ser Glu Ala Gln Ala Ala Ala Trp Leu Glu Ala Ala Arg Gly Ala Arg 
        115                 120                 125             


Met Val Ala Leu Glu Arg Gly Gly Cys Gly Arg Ser Ser Asn Arg Leu 
    130                 135                 140                 


Ala Arg Phe Ala Asp Gly Thr Arg Ala Cys Val Arg Tyr Gly Ile Asn 
145                 150                 155                 160 


Pro Glu Gln Ile Gln Gly Glu Ala Leu Ser Tyr Tyr Leu Ala Arg Leu 
                165                 170                 175     


Leu Gly Leu Gln Arg His Val Pro Pro Leu Ala Leu Ala Arg Val Glu 
            180                 185                 190         


Ala Arg Gly Ala Gln Trp Ala Gln Val Gln Glu Glu Leu Arg Ala Ala 
        195                 200                 205             


His Trp Thr Glu Gly Ser Val Val Ser Leu Thr Arg Trp Leu Pro Asn 
    210                 215                 220                 


Leu Thr Asp Val Val Val Pro Ala Pro Trp Arg Ser Glu Asp Gly Arg 
225                 230                 235                 240 


Leu Arg Pro Leu Arg Asp Ala Gly Gly Glu Leu Ala Asn Leu Ser Gln 
                245                 250                 255     


Ala Glu Leu Val Asp Leu Val Gln Trp Thr Asp Leu Ile Leu Phe Asp 
            260                 265                 270         


Tyr Leu Thr Ala Asn Phe Asp Arg Leu Val Ser Asn Leu Phe Ser Leu 
        275                 280                 285             


Gln Trp Asp Pro Arg Val Met Gln Arg Ala Thr Ser Asn Leu His Arg 
    290                 295                 300                 


Gly Pro Gly Gly Ala Leu Val Phe Leu Asp Asn Glu Ala Gly Leu Val 
305                 310                 315                 320 


His Gly Tyr Arg Val Ala Gly Met Trp Asp Lys Tyr Asn Glu Pro Leu 
                325                 330                 335     


Leu Gln Ser Val Cys Val Phe Arg Glu Arg Thr Ala Arg Arg Val Leu 
            340                 345                 350         


Glu Leu His Arg Gly Gln Asp Ala Ala Ala Arg Leu Leu Arg Leu Tyr 
        355                 360                 365             


Arg Arg His Glu Pro Arg Phe Pro Glu Leu Ala Ala Leu Ala Asp Pro 
    370                 375                 380                 


His Ala Gln Leu Leu Gln Arg Arg Leu Asp Phe Leu Ala Lys His Ile 
385                 390                 395                 400 


Leu His Cys Lys Ala Lys Tyr Gly Arg Arg Ser Gly Thr 
                405                 410             


<210>  1511
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  1511

Leu Pro Asp Pro Gly Asn Ser Thr Trp Pro Pro Gly Ala Gln Ala Gly 
1               5                   10                  15      


Leu Pro Ala Ala Leu Ala Leu Pro Leu Pro Arg Leu Pro Arg Ile Leu 
            20                  25                  30          


Phe Pro Met Ala Gly Arg Pro Ala Arg Pro Ser Ser Asp Phe Val Gly 
        35                  40                  45              


Cys Ala Gln Gly Met Cys Cys His Gly Arg Gln Gly Thr Val His Ile 
    50                  55                  60                  


His Thr Ser Ser Val Ser Cys Trp Thr Pro Cys Pro Val Thr Gly Thr 
65                  70                  75                  80  


Gly Gly Thr Ala Val Ser Arg Lys Asp Arg Val Leu Pro His Arg Arg 
                85                  90                  95      


Gln Val Ser Leu Ala Cys Val Cys Ala Val Gly Glu Arg Ala Gly Gln 
            100                 105                 110         


Leu Trp Ser Gln Lys Pro Val Gln Met Ala Arg Pro Ser Ala Arg His 
        115                 120                 125             


Leu Leu Pro Arg Gly Ser Ser Pro Asn Ser Gln Ala Val Leu Leu Pro 
    130                 135                 140                 


Ser Val Cys Pro Val Pro Trp Pro Pro Val Gly Pro Ser Pro Gly Gln 
145                 150                 155                 160 


Gly Glu Gly Leu Ser Pro Ala Phe Pro Gly Val Gly Thr Asp Arg Gly 
                165                 170                 175     


Asp Ser Trp Ala Leu Val Leu Gln Val 
            180                 185 


<210>  1512
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  1512

Met Gly Ser Gly Asn Pro Ala Pro Gly Gly Val Cys Trp Leu Gln Gln 
1               5                   10                  15      


Gly Gln Glu Ala Thr Cys Ser Leu Val Leu Gln Thr Asp Val Thr Arg 
            20                  25                  30          


Ala Glu Cys Cys Ala Ser Gly Asn Ile Asp Thr Ala Trp Ser Asn Leu 
        35                  40                  45              


Thr His Pro Gly Asn Lys Ile Asn Leu Leu Gly Phe Leu Gly Leu Val 
    50                  55                  60                  


His Cys Leu Pro Cys Lys Asp Ser Cys Asp Gly Val Glu Cys Gly Pro 
65                  70                  75                  80  


Gly Lys Ala Cys Arg Met Leu Gly Gly Arg Pro Arg Cys Glu Cys Ala 
                85                  90                  95      


Pro Asp Cys Ser Gly Leu Pro Ala Arg Leu Gln Val Cys Gly Ser Asp 
            100                 105                 110         


Gly Ala Thr Tyr Arg Asp Glu Cys Glu Leu Arg Ala Ala Arg Cys Arg 
        115                 120                 125             


Gly His Pro Asp Leu Ser Val Met Tyr Arg Gly Arg Cys Arg Lys Ser 
    130                 135                 140                 


Cys Glu His Val Val Cys Pro Arg Pro Gln Ser Cys Val Val Asp Gln 
145                 150                 155                 160 


Thr Gly Ser Ala His Cys Val Val Cys Arg Ala Ala Pro Cys Pro Val 
                165                 170                 175     


Pro Ser Ser Pro Gly Gln Glu Leu Cys Gly Asn Asn Asn Val Thr Tyr 
            180                 185                 190         


Ile Ser Ser Cys His Met Arg Gln Ala Thr Cys Phe Leu Gly Arg Ser 
        195                 200                 205             


Ile Gly Val Arg His Ala Gly Ser Cys Ala Gly Thr Pro Glu Glu Pro 
    210                 215                 220                 


Pro Gly Gly Glu Ser Ala Glu Glu Glu Glu Asn Phe Val 
225                 230                 235         


<210>  1513
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  1513

Gln Phe His Gly Glu Lys Gly Ile Ser Ile Pro Asp His Gly Phe Cys 
1               5                   10                  15      


Gln Pro Ile Ser Ile Pro Leu Cys Thr Asp Ile Ala Tyr Asn Gln Thr 
            20                  25                  30          


Ile Met Pro Asn Leu Leu Gly His Thr Asn Gln Glu Asp Ala Gly Leu 
        35                  40                  45              


Glu Val His Gln Phe Tyr Pro Leu Val Lys Val Gln Cys Ser Pro Glu 
    50                  55                  60                  


Leu Arg Phe Phe Leu Cys Ser Met Tyr Ala Pro Val Cys Thr Val Leu 
65                  70                  75                  80  


Glu Gln Ala Ile Pro Pro Cys Arg Ser Ile Cys Glu Arg Ala Arg Gln 
                85                  90                  95      


Gly Cys Glu Ala Leu Met Asn Lys Phe Gly Phe Gln Trp Pro Glu Arg 
            100                 105                 110         


Leu Arg Cys Glu His Phe Pro Arg His Gly Ala Glu Gln Ile Cys Val 
        115                 120                 125             


Gly Gln Asn His Ser Glu Asp Gly Ala Pro Ala Leu Leu Thr Thr Ala 
    130                 135                 140                 


Pro Pro Pro Gly Leu Gln Pro Gly Ala Gly Gly Thr Pro Gly Gly Pro 
145                 150                 155                 160 


Gly Gly Gly Gly Ala Pro Pro Arg Tyr Ala Thr Leu Glu His Pro Phe 
                165                 170                 175     


His Cys Pro Arg Val Leu Lys Val Pro Ser Tyr Leu Ser Tyr Lys Phe 
            180                 185                 190         


Leu Gly Glu Arg Asp Cys Ala Ala Pro Cys Glu Pro Ala Arg Pro Asp 
        195                 200                 205             


Gly Ser Met Phe Phe Ser Gln Glu Glu Thr Arg Phe Ala Arg Leu Trp 
    210                 215                 220                 


<210>  1514
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  1514

Gln Pro Ser Leu Gln Asp Glu Leu Lys Asp Asn Thr Thr Val Phe Thr 
1               5                   10                  15      


Arg Ile Leu Asp Arg Leu Leu Asp Gly Tyr Asp Asn Arg Leu Arg Pro 
            20                  25                  30          


Gly Leu Gly Glu Arg Val Thr Glu Val Lys Thr Asp Ile Phe Val Thr 
        35                  40                  45              


Ser Phe Gly Pro Val Ser Asp His Asp Met Glu Tyr Thr Ile Asp Val 
    50                  55                  60                  


Phe Phe Arg Gln Ser Trp Lys Asp Glu Arg Leu Lys Phe Lys Gly Pro 
65                  70                  75                  80  


Met Thr Val Leu Arg Leu Asn Asn Leu Met Ala Ser Lys Ile Trp Thr 
                85                  90                  95      


Pro Asp Thr Phe Phe His Asn Gly Lys Lys Ser Val Ala His Asn Met 
            100                 105                 110         


Thr Met Pro Asn Lys Leu Leu Arg Ile Thr Glu Asp Gly Thr Leu Leu 
        115                 120                 125             


Tyr Thr Met Arg Leu Thr Val Arg Ala Glu Cys Pro Met His Leu Glu 
    130                 135                 140                 


Asp Phe Pro Met Asp Ala His Ala Cys Pro Leu Lys Phe Gly Ser Tyr 
145                 150                 155                 160 


Ala Tyr Thr Arg Ala Glu Val Val Tyr Glu Trp Thr Arg Glu Pro Ala 
                165                 170                 175     


Arg Ser Val Val Val Ala Glu Asp Gly Ser Arg Leu Asn Gln Tyr Asp 
            180                 185                 190         


Leu Leu Gly Gln Thr Val Asp Ser Gly Ile Val Gln Ser Ser Thr Gly 
        195                 200                 205             


Glu Tyr Val Val Met Thr Thr His Phe His Leu Lys Arg Lys Ile Gly 
    210                 215                 220                 


<210>  1515
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  1515

Asn Ile Gln Glu Asp Glu Ala Lys Asn Asn Ile Thr Ile Phe Thr Arg 
1               5                   10                  15      


Ile Leu Asp Arg Leu Leu Asp Gly Tyr Asp Asn Arg Leu Arg Pro Gly 
            20                  25                  30          


Leu Gly Asp Ser Ile Thr Glu Val Phe Thr Asn Ile Tyr Val Thr Ser 
        35                  40                  45              


Phe Gly Pro Val Ser Asp Thr Asp Met Glu Tyr Thr Ile Asp Val Phe 
    50                  55                  60                  


Phe Arg Gln Lys Trp Lys Asp Glu Arg Leu Lys Phe Lys Gly Pro Met 
65                  70                  75                  80  


Asn Ile Leu Arg Leu Asn Asn Leu Met Ala Ser Lys Ile Trp Thr Pro 
                85                  90                  95      


Asp Thr Phe Phe His Asn Gly Lys Lys Ser Val Ala His Asn Met Thr 
            100                 105                 110         


Met Pro Asn Lys Leu Leu Arg Ile Gln Asp Asp Gly Thr Leu Leu Tyr 
        115                 120                 125             


Thr Met Arg Leu Thr Val Gln Ala Glu Cys Pro Met His Leu Glu Asp 
    130                 135                 140                 


Phe Pro Met Asp Ala His Ser Cys Pro Leu Lys Phe Gly Ser Tyr Ala 
145                 150                 155                 160 


Tyr Thr Thr Ser Glu Val Thr Tyr Ile Trp Thr Tyr Asn Ala Ser Asp 
                165                 170                 175     


Ser Val Gln Val Ala Pro Asp Gly Ser Arg Leu Asn Gln Tyr Asp Leu 
            180                 185                 190         


Leu Gly Gln Ser Ile Gly Lys Glu Thr Ile Lys Ser Ser Thr Gly Glu 
        195                 200                 205             


Tyr Thr Val Met Thr Ala His Phe His Leu Lys Arg Lys Ile Gly 
    210                 215                 220             


<210>  1516
<211>  231
<212>  PRT
<213>  Homo Sapiens

<400>  1516

Pro Gln Thr Glu Ser Lys Asn Glu Ala Ser Ser Arg Asp Val Val Tyr 
1               5                   10                  15      


Gly Pro Gln Pro Gln Pro Leu Glu Asn Gln Leu Leu Ser Glu Glu Thr 
            20                  25                  30          


Lys Ser Thr Glu Thr Glu Thr Gly Ser Arg Val Gly Lys Leu Pro Glu 
        35                  40                  45              


Ala Ser Arg Ile Leu Asn Thr Ile Leu Ser Asn Tyr Asp His Lys Leu 
    50                  55                  60                  


Arg Pro Gly Ile Gly Glu Lys Pro Thr Val Val Thr Val Glu Ile Ser 
65                  70                  75                  80  


Val Asn Ser Leu Gly Pro Leu Ser Ile Leu Asp Met Glu Tyr Thr Ile 
                85                  90                  95      


Asp Ile Ile Phe Ser Gln Thr Trp Tyr Asp Glu Arg Leu Cys Tyr Asn 
            100                 105                 110         


Asp Thr Phe Glu Ser Leu Val Leu Asn Gly Asn Val Val Ser Gln Leu 
        115                 120                 125             


Trp Ile Pro Asp Thr Phe Phe Arg Asn Ser Lys Arg Thr His Glu His 
    130                 135                 140                 


Glu Ile Thr Met Pro Asn Gln Met Val Arg Ile Tyr Lys Asp Gly Lys 
145                 150                 155                 160 


Val Leu Tyr Thr Ile Arg Met Thr Ile Asp Ala Gly Cys Ser Leu His 
                165                 170                 175     


Met Leu Arg Phe Pro Met Asp Ser His Ser Cys Pro Leu Ser Phe Ser 
            180                 185                 190         


Ser Phe Ser Tyr Pro Glu Asn Glu Met Ile Tyr Lys Trp Glu Asn Phe 
        195                 200                 205             


Lys Leu Glu Ile Asn Glu Lys Asn Ser Trp Lys Leu Phe Gln Phe Asp 
    210                 215                 220                 


Phe Thr Gly Val Ser Asn Lys 
225                 230     


<210>  1517
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  1517

Arg Ser Arg Lys Val Glu Glu Asp Glu Tyr Glu Asp Ser Ser Ser Asn 
1               5                   10                  15      


Gln Lys Trp Val Leu Ala Pro Lys Ser Gln Asp Thr Asp Val Thr Leu 
            20                  25                  30          


Ile Leu Asn Lys Leu Leu Arg Glu Tyr Asp Lys Lys Leu Arg Pro Asp 
        35                  40                  45              


Ile Gly Ile Lys Pro Thr Val Ile Asp Val Asp Ile Tyr Val Asn Ser 
    50                  55                  60                  


Ile Gly Pro Val Ser Ser Ile Asn Met Glu Tyr Gln Ile Asp Ile Phe 
65                  70                  75                  80  


Phe Ala Gln Thr Trp Thr Asp Ser Arg Leu Arg Phe Asn Ser Thr Met 
                85                  90                  95      


Lys Ile Leu Thr Leu Asn Ser Asn Met Val Gly Leu Ile Trp Ile Pro 
            100                 105                 110         


Asp Thr Ile Phe Arg Asn Ser Lys Thr Ala Glu Ala His Trp Ile Thr 
        115                 120                 125             


Thr Pro Asn Gln Leu Leu Arg Ile Trp Asn Asp Gly Lys Ile Leu Tyr 
    130                 135                 140                 


Thr Leu Arg Leu Thr Ile Asn Ala Glu Cys Gln Leu Gln Leu His Asn 
145                 150                 155                 160 


Phe Pro Met Asp Glu His Ser Cys Pro Leu Ile Phe Ser Ser Tyr Gly 
                165                 170                 175     


Tyr Pro Lys Glu Glu Met Ile Tyr Arg Trp Arg Lys Asn Ser Val Glu 
            180                 185                 190         


Ala Ala Asp Gln Lys Ser Trp Arg Leu Tyr Gln Phe Asp Phe Met Gly 
        195                 200                 205             


Leu Arg Asn Thr Thr Glu Ile Val Thr Thr Ser Ala Gly Asp Tyr Val 
    210                 215                 220                 


Val Met Thr Ile Tyr Phe Glu Leu Ser Arg Arg Met Gly 
225                 230                 235         


<210>  1518
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  1518

Ala Ser Asn Ile Lys Met Thr His Gln Arg Cys Ser Ser Ser Met Lys 
1               5                   10                  15      


Gln Thr Cys Lys Gln Glu Thr Arg Met Lys Lys Asp Asp Ser Thr Lys 
            20                  25                  30          


Ala Arg Pro Gln Lys Tyr Glu Gln Leu Leu His Ile Glu Asp Asn Asp 
        35                  40                  45              


Phe Ala Met Arg Pro Gly Phe Gly Gly Ser Pro Val Pro Val Gly Ile 
    50                  55                  60                  


Asp Val His Val Glu Ser Ile Asp Ser Ile Ser Glu Thr Asn Met Asp 
65                  70                  75                  80  


Phe Thr Met Thr Phe Tyr Leu Arg His Tyr Trp Lys Asp Glu Arg Leu 
                85                  90                  95      


Ser Phe Pro Ser Thr Ala Asn Lys Ser Met Thr Phe Asp His Arg Leu 
            100                 105                 110         


Thr Arg Lys Ile Trp Val Pro Asp Ile Phe Phe Val His Ser Lys Arg 
        115                 120                 125             


Ser Phe Ile His Asp Thr Thr Met Glu Asn Ile Met Leu Arg Val His 
    130                 135                 140                 


Pro Asp Gly Asn Val Leu Leu Ser Leu Arg Ile Thr Val Ser Ala Met 
145                 150                 155                 160 


Cys Phe Met Asp Phe Ser Arg Phe Pro Leu Asp Thr Gln Asn Cys Ser 
                165                 170                 175     


Leu Glu Leu Glu Ser Tyr Ala Tyr Asn Glu Asp Asp Leu Met Leu Tyr 
            180                 185                 190         


Trp Lys His Gly Asn Lys Ser Leu Asn Thr Glu Glu His Met Ser Leu 
        195                 200                 205             


Ser Gln Phe Phe Ile Glu Asp Phe Ser Ala Ser Ser Gly Leu Ala Phe 
    210                 215                 220                 


Tyr Ser Ser Thr Gly Trp Tyr Asn Arg Leu Phe Ile Asn Phe Val Leu 
225                 230                 235                 240 


Arg Arg His 
            


<210>  1519
<211>  279
<212>  PRT
<213>  Homo Sapiens

<400>  1519

Leu Ala His Gly Arg Arg Leu Ile Cys Trp Gln Ala Leu Leu Gln Cys 
1               5                   10                  15      


Gln Gly Glu Pro Glu Cys Ser Tyr Ala Tyr Asn Gln Tyr Ala Glu Ala 
            20                  25                  30          


Cys Ala Pro Val Leu Ala Gln His Gly Gly Gly Asp Ala Pro Gly Ala 
        35                  40                  45              


Ala Ala Ala Ala Phe Pro Ala Ser Ala Ala Ser Phe Ser Ser Arg Trp 
    50                  55                  60                  


Arg Cys Pro Ser His Cys Ile Ser Ala Leu Ile Gln Leu Asn His Thr 
65                  70                  75                  80  


Arg Arg Gly Pro Ala Leu Glu Asp Cys Asp Cys Ala Gln Asp Glu Asn 
                85                  90                  95      


Cys Lys Ser Thr Lys Arg Ala Ile Glu Pro Cys Leu Pro Arg Thr Ser 
            100                 105                 110         


Gly Gly Gly Ala Gly Gly Pro Gly Ala Gly Gly Val Met Gly Cys Thr 
        115                 120                 125             


Glu Ala Arg Arg Arg Cys Asp Arg Asp Ser Arg Cys Asn Leu Ala Leu 
    130                 135                 140                 


Ser Arg Tyr Leu Thr Tyr Cys Gly Lys Val Phe Asn Gly Leu Arg Cys 
145                 150                 155                 160 


Thr Asp Glu Cys Arg Thr Val Ile Glu Asp Met Leu Ala Met Pro Lys 
                165                 170                 175     


Ala Ala Leu Leu Asn Asp Cys Val Cys Asp Gly Leu Glu Arg Pro Ile 
            180                 185                 190         


Cys Glu Ser Val Lys Glu Asn Met Ala Arg Leu Cys Phe Gly Ala Glu 
        195                 200                 205             


Leu Gly Asn Gly Pro Gly Ser Ser Gly Ser Asp Gly Gly Leu Asp Asp 
    210                 215                 220                 


Tyr Tyr Asp Glu Asp Tyr Asp Asp Glu Gln Arg Thr Gly Gly Ala Gly 
225                 230                 235                 240 


Gly Glu Gln Pro Leu Asp Asp Asp Asp Gly Val Pro His Pro Pro Arg 
                245                 250                 255     


Pro Gly Ser Gly Ala Ala Ala Ser Gly Gly Arg Gly Asp Leu Pro Tyr 
            260                 265                 270         


Gly Pro Gly Arg Arg Ser Ser 
        275                 


<210>  1520
<211>  317
<212>  PRT
<213>  Homo Sapiens

<400>  1520

Arg Asp Ile Thr Leu Ser Gly His Pro Arg Leu Ser Thr Gln His Val 
1               5                   10                  15      


Val Leu Leu Arg Glu Asp Glu Val Gly Asp Pro Gly Thr Lys Asp Leu 
            20                  25                  30          


Gly His Pro Gln His Gly Ser Pro Ile Gln Glu Thr Gln Ser Glu Val 
        35                  40                  45              


Val Thr Leu Val Ser Pro Leu Pro Gly Ser Asp Met Ala Ala Leu Pro 
    50                  55                  60                  


Ala Trp Arg Ala Thr Ser Gly Leu Thr Leu Trp Pro His Thr Ala Glu 
65                  70                  75                  80  


Gly Arg Asp Leu Leu Gly Ala Glu Asn Arg Ala Leu Thr Gly Gly Gln 
                85                  90                  95      


Gln Ala Glu Asp Pro Thr Leu Ala Ser Gly Ala His Gln Trp Pro Gly 
            100                 105                 110         


Ser Val Glu Lys Leu Gln Gly Ser Val Trp Cys Asp Ala Glu Thr Leu 
        115                 120                 125             


Leu Ser Ser Ser Arg Thr Gly Gly Gln Ala Pro Pro Trp Leu Thr Asp 
    130                 135                 140                 


His Asp Val Gln Met Leu Arg Leu Leu Ala Gln Gly Glu Val Val Asp 
145                 150                 155                 160 


Lys Ala Arg Val Pro Ala His Gly Gln Val Leu Gln Val Gly Phe Ser 
                165                 170                 175     


Thr Glu Ala Ala Leu Gln Asp Leu Ser Ser Pro Arg Leu Ser Gln Leu 
            180                 185                 190         


Cys Ser Gln Gly Leu Cys Gly Leu Ile Lys Arg Pro Gly Asp Leu Pro 
        195                 200                 205             


Glu Val Leu Ser Phe His Val Asp Arg Val Leu Gly Leu Arg Arg Ser 
    210                 215                 220                 


Leu Pro Ala Val Ala Arg Arg Phe His Ser Pro Leu Leu Pro Tyr Arg 
225                 230                 235                 240 


Tyr Thr Asp Gly Gly Ala Arg Pro Val Ile Trp Trp Ala Pro Asp Val 
                245                 250                 255     


Gln His Leu Ser Asp Pro Asp Glu Asp Gln Asn Ser Leu Ala Leu Gly 
            260                 265                 270         


Trp Leu Gln Tyr Gln Ala Leu Leu Ala His Ser Cys Asn Trp Pro Gly 
        275                 280                 285             


Gln Ala Pro Cys Pro Gly Ile His His Thr Glu Trp Ala Arg Leu Ala 
    290                 295                 300                 


Leu Phe Asp Phe Leu Leu Gln Val His Asp Arg Leu Asp 
305                 310                 315         


<210>  1521
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1521

Asp Ala Glu Pro Val Leu Gly Gly Gly Pro Gly Gly Ala Cys Arg Ala 
1               5                   10                  15      


Arg Arg Leu Tyr Val Ser Phe Arg Glu Val Gly Trp His Arg Trp Val 
            20                  25                  30          


Ile Ala Pro Arg Gly Phe Leu Ala Asn Tyr Cys Gln Gly Gln Cys Ala 
        35                  40                  45              


Leu Pro Val Ala Leu Ser Gly Ser Gly Gly Pro Pro Ala Leu Asn His 
    50                  55                  60                  


Ala Val Leu Arg Ala Leu Met His Ala Ala Ala Pro Gly Ala Ala Asp 
65                  70                  75                  80  


Leu Pro Cys Cys Val Pro Ala Arg Leu Ser Pro Ile Ser Val Leu Phe 
                85                  90                  95      


Phe Asp Asn Ser Asp Asn Val Val Leu Arg Gln Tyr Glu Asp Met Val 
            100                 105                 110         


Val Asp Glu Cys Gly Cys Arg 
        115                 


<210>  1522
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  1522

Thr Ala Leu Ala Gly Thr Arg Thr Ala Gln Gly Ser Gly Gly Gly Ala 
1               5                   10                  15      


Gly Arg Gly His Gly Arg Arg Gly Arg Ser Arg Cys Ser Arg Lys Pro 
            20                  25                  30          


Leu His Val Asp Phe Lys Glu Leu Gly Trp Asp Asp Trp Ile Ile Ala 
        35                  40                  45              


Pro Leu Asp Tyr Glu Ala Tyr His Cys Glu Gly Leu Cys Asp Phe Pro 
    50                  55                  60                  


Leu Arg Ser His Leu Glu Pro Thr Asn His Ala Ile Ile Gln Thr Leu 
65                  70                  75                  80  


Leu Asn Ser Met Ala Pro Asp Ala Ala Pro Ala Ser Cys Cys Val Pro 
                85                  90                  95      


Ala Arg Leu Ser Pro Ile Ser Ile Leu Tyr Ile Asp Ala Ala Asn Asn 
            100                 105                 110         


Val Val Tyr Lys Gln Tyr Glu Asp Met Val Val Glu Ala Cys Gly Cys 
        115                 120                 125             


Arg 
    


<210>  1523
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  1523

Leu Pro Phe Val Pro Ile Arg Glu Gln Phe Phe Glu Ile Pro Met Pro 
1               5                   10                  15      


Ser Ile Ile Leu Lys Leu Lys Glu Pro His Thr Met Ser Arg Ser Gln 
            20                  25                  30          


Lys Phe Leu Ile Trp Leu Ser Asp Leu Leu Leu Met Arg Lys Ala Leu 
        35                  40                  45              


Phe Asp His Leu Thr Ala Arg Gly Ile Gln Val Tyr Ile Trp Val Leu 
    50                  55                  60                  


Asn Glu Glu Gln Glu Tyr Lys Arg Ala Phe Asp Leu Gly Ala Thr Gly 
65                  70                  75                  80  


Val Met Thr Asp Tyr Pro Thr Lys Leu Arg Asp Phe Leu His Asn Phe 
                85                  90                  95      


Ser Ala 
        


<210>  1524
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  1524

Arg Arg Pro His Leu Leu His Thr Pro Arg Ala Pro Thr Phe Arg Ile 
1               5                   10                  15      


Arg Leu Gly Ala His Arg Gly Gly Ser Gly Glu Leu Leu Glu Asn Thr 
            20                  25                  30          


Met Glu Ala Met Glu Asn Ser Met Ala Gln Arg Ser Asp Leu Leu Glu 
        35                  40                  45              


Leu Asp Cys Gln Leu Thr Arg Asp Arg Val Val Val Val Ser His Asp 
    50                  55                  60                  


Glu Asn Leu Cys Arg Gln Ser Gly Leu Asn Arg Asp Val Gly Ser Leu 
65                  70                  75                  80  


Asp Phe Glu Asp Leu Pro Leu Tyr Lys Glu Lys Leu Glu Val Tyr Phe 
                85                  90                  95      


Ser Pro Gly His Phe Ala His Gly Ser Asp Arg Arg Met Val Arg Leu 
            100                 105                 110         


Glu Asp Leu Phe Gln Arg Phe Pro Arg Thr Pro Met Ser Val Glu Ile 
        115                 120                 125             


Lys Gly Lys Asn Glu Glu Leu Ile Arg Glu Ile Ala Gly Leu Val Arg 
    130                 135                 140                 


Arg Tyr Asp Arg Asn Glu Ile Thr Ile Trp Ala Ser Glu Lys Ser Ser 
145                 150                 155                 160 


Val Met Lys Lys Cys Lys Ala Ala Asn Pro Glu Met Pro Leu Ser 
                165                 170                 175 


<210>  1525
<211>  360
<212>  PRT
<213>  Homo Sapiens

<400>  1525

Glu Gly Phe Thr Val Glu Ala Leu Trp Gly Lys Thr Glu Glu Glu Ala 
1               5                   10                  15      


Lys Gln Leu Ala Glu Glu Met Asn Ile Ala Phe Tyr Thr Ser Arg Thr 
            20                  25                  30          


Asp Asp Ile Leu Leu His Gln Asp Val Asp Leu Val Cys Ile Ser Ile 
        35                  40                  45              


Pro Pro Pro Leu Thr Arg Gln Ile Ser Val Lys Ala Leu Gly Ile Gly 
    50                  55                  60                  


Lys Asn Val Val Cys Glu Lys Ala Ala Thr Ser Val Asp Ala Phe Arg 
65                  70                  75                  80  


Met Val Thr Ala Ser Arg Tyr Tyr Pro Gln Leu Met Ser Leu Val Gly 
                85                  90                  95      


Asn Val Leu Arg Phe Leu Pro Ala Phe Val Arg Met Lys Gln Leu Ile 
            100                 105                 110         


Ser Glu His Tyr Val Gly Ala Val Met Ile Cys Asp Ala Arg Ile Tyr 
        115                 120                 125             


Ser Gly Ser Leu Leu Ser Pro Ser Tyr Gly Trp Ile Cys Asp Glu Leu 
    130                 135                 140                 


Met Gly Gly Gly Gly Leu His Thr Met Gly Thr Tyr Ile Val Asp Leu 
145                 150                 155                 160 


Leu Thr His Leu Thr Gly Arg Arg Ala Glu Lys Val His Gly Leu Leu 
                165                 170                 175     


Lys Thr Phe Val Arg Gln Asn Ala Ala Ile Arg Gly Ile Arg His Val 
            180                 185                 190         


Thr Ser Asp Asp Phe Cys Phe Phe Gln Met Leu Met Gly Gly Gly Val 
        195                 200                 205             


Cys Ser Thr Val Thr Leu Asn Phe Asn Met Pro Gly Ala Phe Val His 
    210                 215                 220                 


Glu Val Met Val Val Gly Ser Ala Gly Arg Leu Val Ala Arg Gly Ala 
225                 230                 235                 240 


Asp Leu Tyr Gly Gln Lys Asn Ser Ala Thr Gln Glu Glu Leu Leu Leu 
                245                 250                 255     


Arg Asp Ser Leu Ala Val Gly Ala Gly Leu Pro Glu Gln Gly Pro Gln 
            260                 265                 270         


Asp Val Pro Leu Leu Tyr Leu Lys Gly Met Val Tyr Met Val Gln Ala 
        275                 280                 285             


Leu Arg Gln Ser Phe Gln Gly Gln Gly Asp Arg Arg Thr Trp Asp Arg 
    290                 295                 300                 


Thr Pro Val Ser Met Ala Ala Ser Phe Glu Asp Gly Leu Tyr Met Gln 
305                 310                 315                 320 


Ser Val Val Asp Ala Ile Lys Arg Ser Ser Arg Ser Gly Glu Trp Glu 
                325                 330                 335     


Ala Val Glu Val Leu Thr Glu Glu Pro Asp Thr Asn Gln Asn Leu Cys 
            340                 345                 350         


Glu Ala Leu Gln Arg Asn Asn Leu 
        355                 360 


<210>  1526
<211>  333
<212>  PRT
<213>  Homo Sapiens

<400>  1526

Ser Gln Thr Asn Asn Cys Thr Tyr Leu Arg Glu Gln Cys Leu Arg Asp 
1               5                   10                  15      


Ala Asn Gly Cys Lys His Ala Trp Arg Val Met Glu Asp Ala Cys Asn 
            20                  25                  30          


Asp Ser Asp Pro Gly Asp Pro Cys Lys Met Arg Asn Ser Ser Tyr Cys 
        35                  40                  45              


Asn Leu Ser Ile Gln Tyr Leu Val Glu Ser Asn Phe Gln Phe Lys Glu 
    50                  55                  60                  


Cys Leu Cys Thr Asp Asp Phe Tyr Cys Thr Val Asn Lys Leu Leu Gly 
65                  70                  75                  80  


Lys Lys Cys Ile Asn Lys Ser Asp Asn Val Lys Glu Asp Lys Phe Lys 
                85                  90                  95      


Trp Asn Leu Thr Thr Arg Ser His His Gly Phe Lys Gly Met Trp Ser 
            100                 105                 110         


Cys Leu Glu Val Ala Glu Ala Cys Val Gly Asp Val Val Cys Asn Ala 
        115                 120                 125             


Gln Leu Ala Ser Tyr Leu Lys Ala Cys Ser Ala Asn Gly Asn Pro Cys 
    130                 135                 140                 


Asp Leu Lys Gln Cys Gln Ala Ala Ile Arg Phe Phe Tyr Gln Asn Ile 
145                 150                 155                 160 


Pro Phe Asn Ile Ala Gln Met Leu Ala Phe Cys Asp Cys Ala Gln Ser 
                165                 170                 175     


Asp Ile Pro Cys Gln Gln Ser Lys Glu Ala Leu His Ser Lys Thr Cys 
            180                 185                 190         


Ala Val Asn Met Val Pro Pro Pro Thr Cys Leu Ser Val Ile Arg Ser 
        195                 200                 205             


Cys Gln Asn Asp Glu Leu Cys Arg Arg His Tyr Arg Thr Phe Gln Ser 
    210                 215                 220                 


Lys Cys Trp Gln Arg Val Thr Arg Lys Cys His Glu Asp Glu Asn Cys 
225                 230                 235                 240 


Ile Ser Thr Leu Ser Lys Gln Asp Leu Thr Cys Ser Gly Ser Asp Asp 
                245                 250                 255     


Cys Lys Ala Ala Tyr Ile Asp Ile Leu Gly Thr Val Leu Gln Val Gln 
            260                 265                 270         


Cys Thr Cys Arg Thr Ile Thr Gln Ser Glu Glu Ser Leu Cys Lys Ile 
        275                 280                 285             


Phe Gln His Met Leu His Arg Lys Ser Cys Phe Asn Tyr Pro Thr Leu 
    290                 295                 300                 


Ser Asn Val Lys Gly Met Ala Leu Tyr Thr Arg Lys His Ala Asn Lys 
305                 310                 315                 320 


Ile Thr Leu Thr Gly Phe His Ser Pro Phe Asn Gly Glu 
                325                 330             


<210>  1527
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  1527

Pro Ser Ala Ser Lys Glu Pro Asp Asn His Val Tyr Thr Arg Ala Ala 
1               5                   10                  15      


Val Ala Ala Asp Ala Lys Gln Cys Leu Glu Ile Gly Arg Asp Thr Leu 
            20                  25                  30          


Arg Asp Gly Gly Ser Ala Val Asp Ala Ala Ile Ala Ala Leu Leu Cys 
        35                  40                  45              


Val Gly Leu Met Asn Ala His Ser Met Gly Ile Gly Val Gly Leu Phe 
    50                  55                  60                  


Leu Thr Ile Tyr Asn Ser Thr Thr Arg Lys Ala Glu Val Ile Asn Ala 
65                  70                  75                  80  


Arg Glu Val Ala Pro Arg Leu Ala Phe Ala Ser Met Phe Asn Ser Ser 
                85                  90                  95      


Glu Gln Ser Gln Lys Gly Gly Leu Ser Val Ala Val Pro Gly Glu Ile 
            100                 105                 110         


Arg Gly Tyr Glu Leu Ala His Gln Arg His Gly Arg Leu Pro Trp Ala 
        115                 120                 125             


Arg Leu Phe Gln Pro Ser Ile Gln Leu Ala Arg Gln Gly Phe Pro Val 
    130                 135                 140                 


Gly Lys Gly Leu Ala Ala Val Leu Glu Asn Lys Arg Thr Val Ile Glu 
145                 150                 155                 160 


Gln Gln Pro Val Leu Cys Glu Val Phe Cys Arg Asp Arg Lys Val Leu 
                165                 170                 175     


Arg Glu Gly Glu Arg Leu Thr Leu Pro Arg Leu Ala Asp Thr Tyr Glu 
            180                 185                 190         


Met Leu Ala Ile Glu Gly Ala Gln Ala Phe Tyr Asn Gly Ser Leu Met 
        195                 200                 205             


Ala Gln Ile Val Lys Asp Ile Gln Ala Ala Gly Gly Ile Val Thr Ala 
    210                 215                 220                 


Glu Asp Leu Asn Asn Tyr Cys Ala Glu Leu Ile Glu His Pro Leu Asn 
225                 230                 235                 240 


Ile Ser Leu Gly Asp Ala Val Leu Tyr Met Pro Ser Ala Arg Leu Ser 
                245                 250                 255     


Gly Pro Val Leu Ala Leu Ile Leu Asn Ile Leu Lys Gly Tyr Asn Phe 
            260                 265                 270         


Ser Arg Glu Ser Val Glu Thr Pro Glu Gln Lys Gly Leu Thr Tyr His 
        275                 280                 285             


Arg Ile Val Glu Ala Phe Arg Phe Ala Tyr Ala Lys Arg Thr Leu Leu 
    290                 295                 300                 


Gly Asp Pro Lys Phe Val Asp Val Thr Glu Val Val Arg Asn Met Thr 
305                 310                 315                 320 


Ser Glu Phe Phe Ala Ala Gln Leu Arg Ser Gln Ile Ser Asp His Thr 
                325                 330                 335     


Thr His Pro Ile Ser Tyr Tyr Lys Pro Glu Phe Tyr Thr Pro Asp Asp 
            340                 345                 350         


Gly Gly Thr Ala His Leu Ser Val Val Ala Glu Asp Gly Ser Ala Val 
        355                 360                 365             


Ser Ala Thr Ser Thr Ile Asn Leu Tyr Phe Gly Ser Lys Val Cys Ser 
    370                 375                 380                 


Pro Val Ser Gly Ile Leu Phe Asn Asn Met Asp Asp Phe Ser Ser Pro 
385                 390                 395                 400 


Ser Ile Thr Asn Glu Phe Gly Ala Pro Pro Ser Pro Ala Asn Phe Ile 
                405                 410                 415     


Gln Pro Gly Lys Gln Pro Leu Leu Ser Met Cys Pro Thr Ile Met Val 
            420                 425                 430         


Gly Gln Asp Gly Gln Val Arg Met Val Val Gly Ala Ala Gly Gly Thr 
        435                 440                 445             


Gln Ile Thr Thr Asp Thr Ala Leu Ala Ile Ile Tyr Asn Leu Trp Phe 
    450                 455                 460                 


Gly Tyr Asp Val Lys Arg Ala Val Glu Glu Pro Arg Leu His Asn Lys 
465                 470                 475                 480 


Leu Leu Pro Asn Val Thr Thr Val Glu Arg Asn Ile Asp Gln Ala Val 
                485                 490                 495     


Thr Ala Ala Leu Glu Thr Arg His His His Thr Gln Ile Ala Ser Thr 
            500                 505                 510         


Phe Ile Ala Val Val Gln Ala Ile Val Arg Thr Ala Gly Gly Trp Ala 
        515                 520                 525             


Ala Ala Ser Asp Ser Arg Lys Gly Gly Glu Pro Ala Gly Tyr 
    530                 535                 540         


<210>  1528
<211>  513
<212>  PRT
<213>  Homo Sapiens

<400>  1528

Leu Leu Arg Gln Gln Arg Ser Gln Asp Ala Arg Leu Ser Trp Leu Ala 
1               5                   10                  15      


Gly Leu Gln His Arg Val Ala Trp Gly Ala Leu Val Trp Ala Ala Thr 
            20                  25                  30          


Trp Gln Arg Arg Arg Leu Glu Gln Ser Thr Leu His Val His Gln Ser 
        35                  40                  45              


Gln Gln Gln Ala Leu Arg Trp Cys Leu Gln Gly Ala Gln Arg Pro His 
    50                  55                  60                  


Cys Ser Leu Arg Arg Ser Thr Asp Ile Ser Thr Phe Arg Asn His Leu 
65                  70                  75                  80  


Pro Leu Thr Lys Ala Ser Gln Thr Gln Gln Glu Asp Ser Gly Glu Gln 
                85                  90                  95      


Pro Leu Pro Pro Thr Ser Asn Gln Asp Leu Gly Glu Ala Ser Leu Gln 
            100                 105                 110         


Ala Thr Leu Leu Gly Leu Ala Ala Leu Asn Lys Ala Tyr Pro Glu Val 
        115                 120                 125             


Leu Ala Gln Gly Arg Thr Ala Arg Val Thr Leu Thr Ser Pro Trp Pro 
    130                 135                 140                 


Arg Pro Leu Pro Trp Pro Gly Asn Thr Leu Gly Gln Val Gly Thr Pro 
145                 150                 155                 160 


Gly Thr Lys Asp Pro Arg Ala Leu Leu Leu Asp Ala Leu Arg Ser Pro 
                165                 170                 175     


Gly Leu Arg Ala Leu Glu Ala Gly Thr Ala Val Glu Leu Leu Asp Val 
            180                 185                 190         


Phe Leu Gly Leu Glu Thr Asp Gly Glu Glu Leu Ala Gly Ala Ile Ala 
        195                 200                 205             


Ala Gly Asn Pro Gly Ala Pro Leu Arg Glu Arg Ala Ala Glu Leu Arg 
    210                 215                 220                 


Glu Ala Leu Glu Gln Gly Pro Arg Gly Leu Ala Leu Arg Leu Trp Pro 
225                 230                 235                 240 


Lys Leu Gln Val Val Val Thr Leu Asp Ala Gly Gly Gln Ala Glu Ala 
                245                 250                 255     


Val Ala Ala Leu Gly Ala Leu Trp Cys Gln Gly Leu Ala Phe Phe Ser 
            260                 265                 270         


Pro Ala Tyr Ala Ala Ser Gly Gly Val Leu Gly Leu Asn Leu Gln Pro 
        275                 280                 285             


Glu Gln Pro His Gly Leu Tyr Leu Leu Pro Pro Gly Ala Pro Phe Ile 
    290                 295                 300                 


Glu Leu Leu Pro Val Lys Glu Gly Thr Gln Glu Glu Ala Ala Ser Thr 
305                 310                 315                 320 


Leu Leu Leu Ala Glu Ala Gln Gln Gly Lys Glu Tyr Glu Leu Val Leu 
                325                 330                 335     


Thr Asp Arg Ala Ser Leu Thr Arg Cys Arg Leu Gly Asp Val Val Arg 
            340                 345                 350         


Val Val Gly Ala Tyr Asn Gln Cys Pro Val Val Arg Phe Ile Cys Arg 
        355                 360                 365             


Leu Asp Gln Thr Leu Ser Val Arg Gly Glu Asp Ile Gly Glu Asp Leu 
    370                 375                 380                 


Phe Ser Glu Ala Leu Gly Arg Ala Val Gly Gln Trp Ala Gly Ala Lys 
385                 390                 395                 400 


Leu Leu Asp His Gly Cys Val Glu Ser Ser Ile Leu Asp Ser Ser Ala 
                405                 410                 415     


Gly Ser Ala Pro His Tyr Glu Val Phe Val Ala Leu Arg Gly Leu Arg 
            420                 425                 430         


Asn Leu Ser Glu Glu Asn Arg Asp Lys Leu Asp His Cys Leu Gln Glu 
        435                 440                 445             


Ala Ser Pro Arg Tyr Lys Ser Leu Arg Phe Trp Gly Ser Val Gly Pro 
    450                 455                 460                 


Ala Arg Val His Leu Val Gly Gln Gly Ala Phe Arg Ala Leu Arg Ala 
465                 470                 475                 480 


Ala Leu Ala Ala Cys Pro Ser Ser Pro Phe Pro Pro Ala Met Pro Arg 
                485                 490                 495     


Val Leu Arg His Arg His Leu Ala Gln Cys Leu Gln Glu Arg Val Val 
            500                 505                 510         


Ser 
    


<210>  1529
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  1529

Met Met Asn Ile Arg Phe Asn His Pro Leu Tyr Gly Ser Phe Gly Thr 
1               5                   10                  15      


Gln Ile Ile His Ile Gly Ala Phe Gln Gly Met Val Ser Ile Arg Asp 
            20                  25                  30          


Asn Asn Ile Phe Ser Glu Trp Asp Gly Ile Leu Asp Tyr Lys Asn Ala 
        35                  40                  45              


Leu Leu Val Ala Lys Val Phe Asn Lys Met Ala Cys Val Leu Ala Arg 
    50                  55                  60                  


Met Asp Lys Ala Val Phe Pro Ser Leu Asp Asp Ile Ser Lys Ala Leu 
65                  70                  75                  80  


Asp Lys Gln Ala Phe Lys Tyr Tyr Pro Ser Thr Arg Gly Leu Thr Tyr 
                85                  90                  95      


Thr Val Leu Pro Ser Trp Val Lys Asn Leu Ala Gln Tyr Gly Lys Pro 
            100                 105                 110         


Ile Lys Asn Met Cys Arg Asp Asp Pro Thr Tyr Phe Ala Gln Gln Gln 
        115                 120                 125             


Lys Glu Gly Thr Ala Leu Ala Ile Asp Ser Asn Ser Cys Phe Glu Ile 
    130                 135                 140                 


Gln Leu Leu Ser Phe Met Gly Leu Phe Ile Cys Gly Glu Thr Pro Gly 
145                 150                 155                 160 


Leu 
    


<210>  1530
<211>  512
<212>  PRT
<213>  Homo Sapiens

<400>  1530

Gln Trp Arg Gly Leu Ser Ser Ala Leu Arg Ala Leu Glu Ala Gln Arg 
1               5                   10                  15      


Gly Arg Glu Gln Arg Glu Asp Ser Ala Leu Arg Ser Phe Leu Ala Glu 
            20                  25                  30          


Leu Ser Arg Ala Pro Arg Gly Ala Ser Ala Pro Pro Gln Asp Pro Ala 
        35                  40                  45              


Ser Ser Ala Arg Asn Lys Arg Ser His Ser Gly Glu Pro Ala Pro His 
    50                  55                  60                  


Ile Arg Ala Glu Ser His Asp Met Leu Met Met Met Thr Tyr Ser Met 
65                  70                  75                  80  


Val Pro Ile Arg Val Met Val Asp Leu Cys Asn Ser Thr Lys Gly Ile 
                85                  90                  95      


Cys Leu Thr Gly Pro Ser Gly Pro Pro Gly Pro Pro Gly Ala Gly Gly 
            100                 105                 110         


Leu Pro Gly His Asn Gly Leu Asp Gly Gln Pro Gly Pro Gln Gly Pro 
        115                 120                 125             


Lys Gly Glu Lys Gly Ala Asn Gly Lys Arg Gly Lys Met Gly Ile Pro 
    130                 135                 140                 


Gly Ala Ala Gly Asn Pro Gly Glu Arg Gly Glu Lys Gly Asp His Gly 
145                 150                 155                 160 


Glu Leu Gly Leu Gln Gly Asn Glu Gly Pro Pro Gly Gln Lys Gly Glu 
                165                 170                 175     


Lys Gly Asp Lys Gly Asp Val Ser Asn Asp Val Leu Leu Ala Gly Ala 
            180                 185                 190         


Lys Gly Asp Gln Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro 
        195                 200                 205             


Gly Pro Pro Gly Pro Pro Gly Ser Arg Arg Ala Lys Gly Pro Arg Gln 
    210                 215                 220                 


Pro Ser Met Phe Asn Gly Gln Cys Pro Gly Glu Thr Cys Ala Ile Pro 
225                 230                 235                 240 


Asn Asp Asp Thr Leu Val Gly Lys Ala Asp Glu Lys Ala Ser Glu His 
                245                 250                 255     


His Ser Pro Gln Ala Glu Ser Met Ile Thr Ser Ile Gly Asn Pro Val 
            260                 265                 270         


Gln Val Leu Lys Val Thr Glu Thr Phe Gly Thr Trp Ile Arg Glu Ser 
        275                 280                 285             


Ala Asn Lys Ser Asp Asp Arg Ile Trp Val Thr Glu His Phe Ser Gly 
    290                 295                 300                 


Ile Met Val Lys Glu Phe Lys Asp Gln Pro Ser Leu Leu Asn Gly Ser 
305                 310                 315                 320 


Tyr Thr Phe Ile His Leu Pro Tyr Tyr Phe His Gly Cys Gly His Val 
                325                 330                 335     


Val Tyr Asn Asn Ser Leu Tyr Tyr His Lys Gly Gly Ser Asn Thr Leu 
            340                 345                 350         


Val Arg Phe Glu Phe Gly Gln Glu Thr Ser Gln Thr Leu Lys Leu Glu 
        355                 360                 365             


Asn Ala Leu Tyr Phe Asp Arg Lys Tyr Leu Phe Ala Asn Ser Lys Thr 
    370                 375                 380                 


Tyr Phe Asn Leu Ala Val Asp Glu Lys Gly Leu Trp Ile Ile Tyr Ala 
385                 390                 395                 400 


Ser Ser Val Asp Gly Ser Ser Ile Leu Val Ala Gln Leu Asp Glu Arg 
                405                 410                 415     


Thr Phe Ser Val Val Gln His Val Asn Thr Thr Tyr Pro Lys Ser Lys 
            420                 425                 430         


Ala Gly Asn Ala Phe Ile Ala Arg Gly Ile Leu Tyr Val Thr Asp Thr 
        435                 440                 445             


Lys Asp Met Arg Val Thr Phe Ala Phe Asp Leu Leu Gly Gly Lys Gln 
    450                 455                 460                 


Ile Asn Ala Asn Phe Asp Leu Arg Thr Ser Gln Ser Val Leu Ala Met 
465                 470                 475                 480 


Leu Ala Tyr Asn Met Arg Asp Gln His Leu Tyr Ser Trp Glu Asp Gly 
                485                 490                 495     


His Leu Met Leu Tyr Pro Val Gln Phe Leu Ser Thr Thr Leu Asn Gln 
            500                 505                 510         


<210>  1531
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  1531

Lys Glu Glu Val Lys Ser Gly Thr Lys Gly Ser Gln Pro Met Ser Pro 
1               5                   10                  15      


Ser Asp Phe Leu Asp Lys Leu Met Gly Arg Thr Ser Gly Tyr Asp Ala 
            20                  25                  30          


Arg Ile Arg Pro Asn Phe Lys Gly Pro Pro Val Asn Val Thr Cys Asn 
        35                  40                  45              


Ile Phe Ile Asn Ser Phe Ser Ser Ile Thr Lys Thr Thr Met Asp Tyr 
    50                  55                  60                  


Arg Val Asn Val Phe Leu Arg Gln Gln Trp Asn Asp Pro Arg Leu Ser 
65                  70                  75                  80  


Tyr Arg Glu Tyr Pro Asp Asp Ser Leu Asp Leu Asp Pro Ser Met Leu 
                85                  90                  95      


Asp Ser Ile Trp Lys Pro Asp Leu Phe Phe Ala Asn Glu Lys Gly Ala 
            100                 105                 110         


Asn Phe His Glu Val Thr Thr Asp Asn Lys Leu Leu Arg Ile Phe Lys 
        115                 120                 125             


Asn Gly Asn Val Leu Tyr Ser Ile Arg Leu Thr Leu Ile Leu Ser Cys 
    130                 135                 140                 


Leu Met Asp Leu Lys Asn Phe Pro Met Asp Ile Gln Thr Cys Thr Met 
145                 150                 155                 160 


Gln Leu Glu Ser Phe Gly Tyr Thr Met Lys Asp Leu Val Phe Glu Trp 
                165                 170                 175     


Leu Glu Asp Ala Pro Ala Val Gln Val Ala Glu Gly Leu Thr Leu Pro 
            180                 185                 190         


Gln Phe Ile Leu Arg Asp Glu Lys Asp Leu Gly Cys Cys Thr Lys His 
        195                 200                 205             


Tyr Asn Thr Gly Lys Phe Thr Cys Ile Glu Val Lys Phe His Leu Glu 
    210                 215                 220                 


Arg Gln Met Gly Tyr 
225                 


<210>  1532
<211>  330
<212>  PRT
<213>  Homo Sapiens

<400>  1532

Val Thr Ala Gln Arg Val Arg Ala His Leu Glu Ala Ala Gly His Val 
1               5                   10                  15      


Cys Val Leu Lys Asp Ala Phe Asp Phe Glu Ser Arg Ser Glu Ile Ala 
            20                  25                  30          


Asn Leu Ile Leu Ala Glu Asn Cys Glu Ala Ala Leu Ala Leu His Leu 
        35                  40                  45              


Tyr Arg Gly Gly Arg Leu Leu Gln Gly His Arg Ile Pro Phe Gly Val 
    50                  55                  60                  


Ile Phe Gly Gly Thr Asp Val Asn Glu Asp Ala Asn Gln Ala Glu Lys 
65                  70                  75                  80  


Asn Thr Val Met Gly Arg Val Leu Glu Glu Ala Arg Phe Ala Val Ala 
                85                  90                  95      


Phe Thr Glu Ser Met Lys Glu Met Ala Gln Ala Gln Trp Pro His Ala 
            100                 105                 110         


Lys Gly Lys Val Tyr Val Gln Ser Gln Gly Ile Ala Thr Thr Pro Asn 
        115                 120                 125             


Ala Ala Phe Asn Trp Asn Thr Phe Leu Gln Arg Ser Glu Ile Asn Gln 
    130                 135                 140                 


Ser Ala Asp Asn Leu His Ile Phe Leu Leu Ile Cys Gly Leu Arg Gln 
145                 150                 155                 160 


Val Lys Asp Pro Leu Tyr Leu Val Asp Ala Phe Ser Ala Trp His Gln 
                165                 170                 175     


Glu Glu Pro Asn Val His Leu Val Ile Val Gly Pro Glu Val Asp Pro 
            180                 185                 190         


Val Phe Thr Arg Glu Val Lys Ala Lys Val Lys Arg Ala Ala Gly Val 
        195                 200                 205             


Arg Leu Ile Gly Glu Met Pro Gln Glu Asp Leu His Ala Val Val Lys 
    210                 215                 220                 


Asn Cys Phe Ala Val Val Asn Ser Ser Val Ser Glu Gly Met Ser Ala 
225                 230                 235                 240 


Ala Ile Leu Glu Ala Met Asp Leu Glu Val Pro Val Leu Ala Arg Asn 
                245                 250                 255     


Ile Pro Gly Asn Ala Ala Val Val Lys His Glu Val Thr Gly Leu Leu 
            260                 265                 270         


Phe Ser Asn Pro Gln Glu Phe Val His Leu Ala Lys Arg Leu Val Ser 
        275                 280                 285             


Asp Pro Ala Leu Glu Lys Glu Ile Val Val Asn Gly Arg Glu Tyr Val 
    290                 295                 300                 


Arg Met Tyr His Ser Trp Gln Val Glu Arg Asp Thr Tyr Gln Gln Leu 
305                 310                 315                 320 


Ile Arg Lys Leu Glu Gly Ser Thr Glu Asp 
                325                 330 


<210>  1533
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  1533

Ala Ser Ser Gly Asn Leu Arg Thr Phe Val Gly Cys Ala Val Arg Glu 
1               5                   10                  15      


Phe Thr Phe Leu Ala Lys Lys Pro Gly Cys Arg Gly Leu Arg Ile Thr 
            20                  25                  30          


Thr Asp Ala Cys Trp Gly Arg Cys Glu Thr Trp Glu Lys Pro Ile Leu 
        35                  40                  45              


Glu Pro Pro Tyr Ile Glu Ala His His Arg Val Cys Thr Tyr Asn Glu 
    50                  55                  60                  


Thr Lys Gln Val Thr Val Lys Leu Pro Asn Cys Ala Pro Gly Val Asp 
65                  70                  75                  80  


Pro Phe Tyr Thr Tyr Pro Val Ala Ile Arg Cys Asp Cys Gly Ala Cys 
                85                  90                  95      


Ser Thr Ala Thr Thr Glu Cys Glu Thr Ile 
            100                 105     


<210>  1534
<211>  230
<212>  PRT
<213>  Homo Sapiens

<400>  1534

Arg Ile His Gln Leu Ala Leu Thr Gly Glu Lys Arg Ala Asp Ile Gln 
1               5                   10                  15      


Leu Asn Ser Phe Gly Phe Tyr Thr Asn Gly Ser Leu Glu Val Glu Leu 
            20                  25                  30          


Ser Val Leu Arg Leu Gly Leu Arg Glu Ala Glu Glu Lys Ser Leu Leu 
        35                  40                  45              


Val Gly Phe Ser Leu Ser Arg Val Arg Ser Gly Arg Val Arg Ser Tyr 
    50                  55                  60                  


Ser Thr Arg Asp Phe Gln Asp Cys Pro Leu Gln Lys Asn Ser Ser Ser 
65                  70                  75                  80  


Phe Leu Val Leu Phe Leu Ile Asn Thr Lys Asp Leu Gln Val Gln Val 
                85                  90                  95      


Arg Lys Tyr Gly Glu Gln Lys Thr Leu Phe Ile Phe Pro Gly Leu Leu 
            100                 105                 110         


Pro Glu Ala Pro Ser Lys Pro Gly Leu Pro Lys Pro Gln Ala Thr Val 
        115                 120                 125             


Pro Arg Lys Val Asp Gly Gly Gly Thr Ser Ala Ala Ser Lys Pro Lys 
    130                 135                 140                 


Ser Thr Pro Ala Val Ile Gln Gly Pro Ser Gly Lys Asp Lys Asp Leu 
145                 150                 155                 160 


Val Leu Gly Leu Ser His Leu Asn Asn Ser Tyr Asn Phe Ser Phe His 
                165                 170                 175     


Val Val Ile Gly Ser Gln Ala Glu Glu Gly Gln Tyr Ser Leu Asn Phe 
            180                 185                 190         


His Asn Cys Asn Asn Ser Val Pro Gly Lys Glu His Pro Phe Asp Ile 
        195                 200                 205             


Thr Val Met Ile Arg Glu Lys Asn Pro Asp Gly Phe Leu Ser Ala Ala 
    210                 215                 220                 


Glu Met Pro Leu Phe Lys 
225                 230 


<210>  1535
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  1535

Thr His Trp Cys Gln Gly Thr Gln Arg Val Pro Lys Pro Gly Cys Gly 
1               5                   10                  15      


Gln Gly Gly Arg Ala Asn Cys Pro Asn Ser Gly Ala Asn Ala Thr Ala 
            20                  25                  30          


Asn Gly Thr Ala Ala Pro Ala Ala Ala Ala Ala Ala Ala Thr Ala Ser 
        35                  40                  45              


Gly Asn Gly Pro Pro Gly Gly Ala Leu Tyr Ser Trp Glu Thr Gly Asp 
    50                  55                  60                  


Asp Arg Phe Leu Phe Arg Asn Phe His Thr Gly Ile Trp Tyr Ser Cys 
65                  70                  75                  80  


Glu Glu Glu Leu Ser Gly Leu Gly Glu Lys Cys Arg Ser Phe Ile Asp 
                85                  90                  95      


Leu Ala Pro Ala Ser Glu Lys 
            100             


<210>  1536
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  1536

His Trp Cys Glu Gly Thr Arg Arg Val Val Lys Pro Leu Cys Gln Asp 
1               5                   10                  15      


Gln Pro Gly Gly Gln His Cys Ile His Phe Lys Arg Asp Asn Ser Ser 
            20                  25                  30          


Asn Gly Arg Met Asp Asn Asn Ser Gln Ala Val Leu Tyr Ile Trp Glu 
        35                  40                  45              


Leu Gly Asp Asp Lys Phe Ile Gln Arg Gly Phe His Val Gly Leu Trp 
    50                  55                  60                  


Gln Ser Cys Glu Glu Ser Leu Asn Gly Glu Asp Glu Lys Cys Arg Ser 
65                  70                  75                  80  


Phe Arg Ser Val Val Pro Ala Glu Glu Gln Gly 
                85                  90      


<210>  1537
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  1537

Ser Gly Pro Arg Arg Gln Trp His Pro Leu Ala Ser Cys Ser Ser Trp 
1               5                   10                  15      


Ser Arg Pro Gln Ser Gln Gly Ser Thr Pro Gly Val Leu Cys Lys Thr 
            20                  25                  30          


Gly Met Gly Arg Glu Pro Ile Pro Glu Thr Gln Cys His Phe Ala Asn 
        35                  40                  45              


Ser Met Cys Ser Leu His Val Ser Val Pro Tyr Phe Gly Asn Ser Pro 
    50                  55                  60                  


Asn Ile Ser Asn Phe Phe Arg Trp Ser Leu Ala Leu Ser Pro Arg Gln 
65                  70                  75                  80  


Trp Cys Asp Leu Gly Ser Leu Gln Pro Pro Ser Pro Arg Phe Lys Gly 
                85                  90                  95      


Phe Ser Cys Leu Ser Leu Pro Ser Ser Trp Asp Tyr Arg Arg Ala Pro 
            100                 105                 110         


Ser Pro Ala Asn Phe Cys Ile Leu Val Glu Met Gly Phe His His Val 
        115                 120                 125             


Gly Gln Ala Asp Leu Glu Leu Leu Thr Ser Ala Asp Leu Pro Thr Ser 
    130                 135                 140                 


Ala Ser Gln Ser Ala Gly Ile Thr Gly Val Ser His His Ala Trp Pro 
145                 150                 155                 160 


Gln Thr Leu Ser Leu Leu Leu Tyr 
                165             


<210>  1538
<211>  400
<212>  PRT
<213>  Homo Sapiens

<400>  1538

Ala Ala Gly Leu Gln Gly Arg Pro Ala Arg Arg Cys Tyr Ala Val Gly 
1               5                   10                  15      


Pro Ala Gln Ser Pro Pro Thr Phe Gly Phe Leu Leu Asp Ile Asp Gly 
            20                  25                  30          


Val Leu Val Arg Gly His Arg Val Ile Pro Ala Ala Leu Lys Ala Phe 
        35                  40                  45              


Arg Arg Leu Val Asn Ser Gln Gly Gln Leu Arg Val Pro Val Val Phe 
    50                  55                  60                  


Val Thr Asn Ala Gly Asn Ile Leu Gln His Ser Lys Ala Gln Glu Leu 
65                  70                  75                  80  


Ser Ala Leu Leu Gly Cys Glu Val Asp Ala Asp Gln Val Ile Leu Ser 
                85                  90                  95      


His Ser Pro Met Lys Leu Phe Ser Glu Tyr His Glu Lys Arg Met Leu 
            100                 105                 110         


Val Ser Gly Gln Gly Pro Val Met Glu Asn Ala Gln Gly Leu Gly Phe 
        115                 120                 125             


Arg Asn Val Val Thr Val Asp Glu Leu Arg Met Ala Phe Pro Leu Leu 
    130                 135                 140                 


Asp Met Val Asp Leu Glu Arg Arg Leu Lys Thr Thr Pro Leu Pro Arg 
145                 150                 155                 160 


Asn Asp Phe Pro Arg Ile Glu Gly Val Leu Leu Leu Gly Glu Pro Val 
                165                 170                 175     


Arg Trp Glu Thr Ser Leu Gln Leu Ile Met Asp Val Leu Leu Ser Asn 
            180                 185                 190         


Gly Ser Pro Gly Ala Gly Leu Ala Thr Pro Pro Tyr Pro His Leu Pro 
        195                 200                 205             


Val Leu Ala Ser Asn Met Asp Leu Leu Trp Met Ala Glu Ala Lys Met 
    210                 215                 220                 


Pro Arg Phe Gly His Gly Thr Phe Leu Leu Cys Leu Glu Thr Ile Tyr 
225                 230                 235                 240 


Gln Lys Val Thr Gly Lys Glu Leu Arg Tyr Glu Gly Leu Met Gly Lys 
                245                 250                 255     


Pro Ser Ile Leu Thr Tyr Gln Tyr Ala Glu Asp Leu Ile Arg Arg Gln 
            260                 265                 270         


Ala Glu Arg Arg Gly Trp Ala Ala Pro Ile Arg Lys Leu Tyr Ala Val 
        275                 280                 285             


Gly Asp Asn Pro Met Ser Asp Val Tyr Gly Ala Asn Leu Phe His Gln 
    290                 295                 300                 


Tyr Leu Gln Lys Ala Thr His Asp Gly Ala Pro Glu Leu Gly Ala Gly 
305                 310                 315                 320 


Gly Thr Arg Gln Gln Gln Pro Ser Ala Ser Gln Ser Cys Ile Ser Ile 
                325                 330                 335     


Leu Val Cys Thr Gly Val Tyr Asn Pro Arg Asn Pro Gln Ser Thr Glu 
            340                 345                 350         


Pro Val Leu Gly Gly Gly Glu Pro Pro Phe His Gly His Arg Asp Leu 
        355                 360                 365             


Cys Phe Ser Pro Gly Leu Met Glu Ala Ser His Val Val Asn Asp Val 
    370                 375                 380                 


Asn Glu Ala Val Gln Leu Val Phe Arg Lys Glu Gly Trp Ala Leu Glu 
385                 390                 395                 400 


<210>  1539
<211>  502
<212>  PRT
<213>  Homo Sapiens

<400>  1539

Ile Lys Gly Glu Ala Lys Lys Glu Lys Gly Met Thr Phe Leu Pro Thr 
1               5                   10                  15      


Thr Val Ser Gly Leu Arg Glu Glu Glu Arg Lys Glu Lys Gly Val Ala 
            20                  25                  30          


Phe Leu Ala Thr Thr Glu Leu Pro Ala Arg Ser Ile Asp Leu Ser Ala 
        35                  40                  45              


Leu Asn Leu Thr Glu Leu Val Asn Gly Met Leu Ser Arg Ala Leu Lys 
    50                  55                  60                  


Asp Ser Lys Lys Phe Phe Ser Leu Leu Ser Val Thr Ser Tyr Ser Ser 
65                  70                  75                  80  


Phe Ala Phe His Lys Phe Ser Val Ala Val Tyr Asn Ile Ser Asn Leu 
                85                  90                  95      


Lys Thr Val Asp Pro Ala Lys Phe Pro Thr Arg Tyr Cys Tyr Cys Leu 
            100                 105                 110         


Asn Asn Arg Thr Asn Asp Leu Ser Asp Phe Thr Ala Leu Leu Val Asp 
        115                 120                 125             


Ile Ile Gly Asn Ser Thr Ser Tyr Leu Thr Glu Ile Phe Lys Ser Thr 
    130                 135                 140                 


Ser Ile Leu Ser Val Asn Gln Ser Asn Glu Ser Asp Cys Ile Phe Ile 
145                 150                 155                 160 


Cys Val Met Thr Gly Lys Ser Gly Arg Asn Leu Ser Asp Phe Trp Glu 
                165                 170                 175     


Ile Glu Glu Lys Tyr Pro Ile Ile Asn Tyr Thr Phe Thr Ser Gly Leu 
            180                 185                 190         


Ser Gly Val Leu Gly Ala Ala Thr Arg Gly Thr Ala Arg Thr Ser Lys 
        195                 200                 205             


Pro Thr Thr Lys Ser Gln Lys Thr Leu Pro Ser Thr Ser Pro Gly His 
    210                 215                 220                 


Trp Thr Gln Ser Thr Pro Trp Ala Ser Ala Leu Arg Ser Ser Pro Trp 
225                 230                 235                 240 


Thr Glu Thr Ala Ala Pro Ser Glu Thr Glu Glu Thr Leu Asn Thr Gly 
                245                 250                 255     


Arg Pro Pro Glu Leu Pro Ala Arg Ala Thr Ala Thr Trp Phe Ser Ala 
            260                 265                 270         


Ser His Thr Leu Pro Ala Leu Ala Thr Arg Arg Val Ala Arg Thr Gln 
        275                 280                 285             


Trp Leu Thr Ala Asp Arg Gln Thr Trp Ala Ser Ile Ser Ser Val Pro 
    290                 295                 300                 


Trp Ala Gln Thr Ile Ser Glu Lys Lys Pro Gly Gly Ser Leu Trp Glu 
305                 310                 315                 320 


Thr Arg Ser Ser Pro Pro Thr Thr Ala Gly Thr Glu Glu Ala Met Asn 
                325                 330                 335     


Thr Thr Ser Leu Leu Ala Pro Ala Ala Glu Ile Met Ala Thr Pro Gly 
            340                 345                 350         


Ser Pro Ser Gln Ala Ser Pro Thr Leu Gly Ala Phe Thr His Gly Thr 
        355                 360                 365             


Gln Thr Pro Ser Pro Thr Lys Ala Thr Ala Pro Arg Tyr Pro Gln Thr 
    370                 375                 380                 


Gly Asp Leu Ser Ala Glu Trp Pro Phe Thr Ala Gly Glu Glu Pro Val 
385                 390                 395                 400 


Leu Val Pro Arg Pro His Gln Val Ser Arg Cys Pro Gln Pro Leu Phe 
                405                 410                 415     


Lys Val Gly Ala Met Ala Ala Ala Pro Leu Thr Leu Ala Ile Gln Arg 
            420                 425                 430         


Leu Asn Pro Cys Leu Met Glu Leu Cys Gln Phe Phe Gln Gln Cys Leu 
        435                 440                 445             


Cys Met Ser Gln Arg Ser Pro Arg Thr Glu Asp Met Arg Tyr Cys Leu 
    450                 455                 460                 


Glu Tyr Tyr Ser Trp Phe Leu Lys Asn Ala Thr Tyr Ile Cys Gln Arg 
465                 470                 475                 480 


Val Lys Arg Val Ser His Ser His Thr Leu Lys Gln Lys Cys Leu Glu 
                485                 490                 495     


Asn Ile Cys Lys Ser Val 
            500         


<210>  1540
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1540

Gln Met Ser Gln Ala Leu Cys Phe Ser Lys Ile Gly Gly Glu Asp Gly 
1               5                   10                  15      


Asp Ile His Arg Gly Phe Gln Ser Leu Leu Val Ala Ile Asn Arg Thr 
            20                  25                  30          


Asp Thr Glu Tyr Val Leu Arg Thr Ala Asn Gly Leu Phe Gly Glu Lys 
        35                  40                  45              


Ser Tyr Asp Phe Leu Thr Gly Phe Thr Asp Ser Cys Gly Lys Phe Tyr 
    50                  55                  60                  


Gln Ala Thr Ile Lys Gln Leu Asp Phe Val Asn Asp Thr Glu Lys Ser 
65                  70                  75                  80  


Thr Thr Arg Val Asn Ser Trp Val Ala Asp Lys Thr Lys Gly Glu Asn 
                85                  90                  95      


Ile Leu Leu Phe Tyr Phe Asp Asn Ile Leu Asn Ser Phe Ile Val Ser 
            100                 105                 110         


Ser Leu Gln Asn Cys Gln Ile 
        115                 


<210>  1541
<211>  353
<212>  PRT
<213>  Homo Sapiens

<400>  1541

Met Glu Lys Thr Leu Glu Thr Val Pro Leu Glu Arg Lys Lys Arg Glu 
1               5                   10                  15      


Lys Glu Gln Phe Arg Lys Leu Phe Ile Gly Gly Leu Ser Phe Glu Thr 
            20                  25                  30          


Thr Glu Glu Ser Leu Arg Asn Tyr Tyr Glu Gln Trp Gly Lys Leu Thr 
        35                  40                  45              


Asp Cys Val Val Met Arg Asp Pro Ala Ser Lys Arg Ser Arg Gly Phe 
    50                  55                  60                  


Gly Phe Val Thr Phe Ser Ser Met Ala Glu Val Asp Ala Ala Met Ala 
65                  70                  75                  80  


Ala Arg Pro His Ser Ile Asp Gly Arg Val Val Glu Pro Lys Arg Ala 
                85                  90                  95      


Val Ala Arg Glu Glu Ser Gly Lys Pro Gly Ala His Val Thr Val Lys 
            100                 105                 110         


Lys Leu Phe Val Gly Gly Ile Lys Glu Asp Thr Glu Glu His His Leu 
        115                 120                 125             


Arg Asp Tyr Phe Glu Glu Tyr Gly Lys Ile Asp Thr Ile Glu Ile Ile 
    130                 135                 140                 


Thr Asp Arg Gln Ser Gly Lys Lys Arg Gly Phe Gly Phe Val Thr Phe 
145                 150                 155                 160 


Asp Asp His Asp Pro Val Asp Lys Ile Val Leu Gln Lys Tyr His Thr 
                165                 170                 175     


Ile Asn Gly His Asn Ala Glu Val Arg Lys Ala Leu Ser Arg Gln Glu 
            180                 185                 190         


Met Gln Glu Val Gln Ser Ser Arg Ser Gly Arg Gly Gly Asn Phe Gly 
        195                 200                 205             


Phe Gly Asp Ser Arg Gly Gly Gly Gly Asn Phe Gly Pro Gly Pro Gly 
    210                 215                 220                 


Ser Asn Phe Arg Gly Gly Ser Asp Gly Tyr Gly Ser Gly Arg Gly Phe 
225                 230                 235                 240 


Gly Asp Gly Tyr Asn Gly Tyr Gly Gly Gly Pro Gly Gly Gly Asn Phe 
                245                 250                 255     


Gly Gly Ser Pro Gly Tyr Gly Gly Gly Arg Gly Gly Tyr Gly Gly Gly 
            260                 265                 270         


Gly Pro Gly Tyr Gly Asn Gln Gly Gly Gly Tyr Gly Gly Gly Tyr Asp 
        275                 280                 285             


Asn Tyr Gly Gly Gly Asn Tyr Gly Ser Gly Asn Tyr Asn Asp Phe Gly 
    290                 295                 300                 


Asn Tyr Asn Gln Gln Pro Ser Asn Tyr Gly Pro Met Lys Ser Gly Asn 
305                 310                 315                 320 


Phe Gly Gly Ser Arg Asn Met Gly Gly Pro Tyr Gly Gly Gly Asn Tyr 
                325                 330                 335     


Gly Pro Gly Gly Ser Gly Gly Ser Gly Gly Tyr Gly Gly Arg Ser Arg 
            340                 345                 350         


Tyr 
    


<210>  1542
<211>  388
<212>  PRT
<213>  Homo Sapiens

<400>  1542

Val Asp Ser Gly Asn Asp Val Thr Asp Ile Ala Asp Asp Gly Cys Pro 
1               5                   10                  15      


Lys Pro Pro Glu Ile Ala His Gly Tyr Val Glu His Ser Val Arg Tyr 
            20                  25                  30          


Gln Cys Lys Asn Tyr Tyr Lys Leu Arg Thr Glu Gly Asp Gly Val Tyr 
        35                  40                  45              


Thr Leu Asn Asp Lys Lys Gln Trp Ile Asn Lys Ala Val Gly Asp Lys 
    50                  55                  60                  


Leu Pro Glu Cys Glu Ala Asp Asp Gly Cys Pro Lys Pro Pro Glu Ile 
65                  70                  75                  80  


Ala His Gly Tyr Val Glu His Ser Val Arg Tyr Gln Cys Lys Asn Tyr 
                85                  90                  95      


Tyr Lys Leu Arg Thr Glu Gly Asp Gly Val Tyr Thr Leu Asn Asn Glu 
            100                 105                 110         


Lys Gln Trp Ile Asn Lys Ala Val Gly Asp Lys Leu Pro Glu Cys Glu 
        115                 120                 125             


Ala Val Cys Gly Lys Pro Lys Asn Pro Ala Asn Pro Val Gln Arg Ile 
    130                 135                 140                 


Leu Gly Gly His Leu Asp Ala Lys Gly Ser Phe Pro Trp Gln Ala Lys 
145                 150                 155                 160 


Met Val Ser His His Asn Leu Thr Thr Gly Ala Thr Leu Ile Asn Glu 
                165                 170                 175     


Gln Trp Leu Leu Thr Thr Ala Lys Asn Leu Phe Leu Asn His Ser Glu 
            180                 185                 190         


Asn Ala Thr Ala Lys Asp Ile Ala Pro Thr Leu Thr Leu Tyr Val Gly 
        195                 200                 205             


Lys Lys Gln Leu Val Glu Ile Glu Lys Val Val Leu His Pro Asn Tyr 
    210                 215                 220                 


Ser Gln Val Asp Ile Gly Leu Ile Lys Leu Lys Gln Lys Val Ser Val 
225                 230                 235                 240 


Asn Glu Arg Val Met Pro Ile Cys Leu Pro Ser Lys Asp Tyr Ala Glu 
                245                 250                 255     


Val Gly Arg Val Gly Tyr Val Ser Gly Trp Gly Arg Asn Ala Asn Phe 
            260                 265                 270         


Lys Phe Thr Asp His Leu Lys Tyr Val Met Leu Pro Val Ala Asp Gln 
        275                 280                 285             


Asp Gln Cys Ile Arg His Tyr Glu Gly Ser Thr Val Pro Glu Lys Lys 
    290                 295                 300                 


Thr Pro Lys Ser Pro Val Gly Val Gln Pro Ile Leu Asn Glu His Thr 
305                 310                 315                 320 


Phe Cys Ala Gly Met Ser Lys Tyr Gln Glu Asp Thr Cys Tyr Gly Asp 
                325                 330                 335     


Ala Gly Ser Ala Phe Ala Val His Asp Leu Glu Glu Asp Thr Trp Tyr 
            340                 345                 350         


Ala Thr Gly Ile Leu Ser Phe Asp Lys Ser Cys Ala Val Ala Glu Tyr 
        355                 360                 365             


Gly Val Tyr Val Lys Val Thr Ser Ile Gln Asp Trp Val Gln Lys Thr 
    370                 375                 380                 


Ile Ala Glu Asn 
385             


<210>  1543
<211>  348
<212>  PRT
<213>  Homo Sapiens

<400>  1543

Met Ser Asp Leu Gly Ala Val Ile Ser Leu Leu Leu Trp Gly Arg Gln 
1               5                   10                  15      


Leu Phe Ala Leu Tyr Ser Gly Asn Asp Val Thr Asp Ile Ser Asp Asp 
            20                  25                  30          


Arg Phe Pro Lys Pro Pro Glu Ile Ala Asn Gly Tyr Val Glu His Leu 
        35                  40                  45              


Phe Arg Tyr Gln Cys Lys Asn Tyr Tyr Arg Leu Arg Thr Glu Gly Asp 
    50                  55                  60                  


Gly Val Tyr Thr Leu Asn Asp Lys Lys Gln Trp Ile Asn Lys Ala Val 
65                  70                  75                  80  


Gly Asp Lys Leu Pro Glu Cys Glu Ala Val Cys Gly Lys Pro Lys Asn 
                85                  90                  95      


Pro Ala Asn Pro Val Gln Arg Ile Leu Gly Gly His Leu Asp Ala Lys 
            100                 105                 110         


Gly Ser Phe Pro Trp Gln Ala Lys Met Val Ser His His Asn Leu Thr 
        115                 120                 125             


Thr Gly Ala Thr Leu Ile Asn Glu Gln Trp Leu Leu Thr Thr Ala Lys 
    130                 135                 140                 


Asn Leu Phe Leu Asn His Ser Glu Asn Ala Thr Ala Lys Asp Ile Ala 
145                 150                 155                 160 


Pro Thr Leu Thr Leu Tyr Val Gly Lys Lys Gln Leu Val Glu Ile Glu 
                165                 170                 175     


Lys Val Val Leu His Pro Asn Tyr His Gln Val Asp Ile Gly Leu Ile 
            180                 185                 190         


Lys Leu Lys Gln Lys Val Leu Val Asn Glu Arg Val Met Pro Ile Cys 
        195                 200                 205             


Leu Pro Ser Lys Asn Tyr Ala Glu Val Gly Arg Val Gly Tyr Val Ser 
    210                 215                 220                 


Gly Trp Gly Gln Ser Asp Asn Phe Lys Leu Thr Asp His Leu Lys Tyr 
225                 230                 235                 240 


Val Met Leu Pro Val Ala Asp Gln Tyr Asp Cys Ile Thr His Tyr Glu 
                245                 250                 255     


Gly Ser Thr Cys Pro Lys Trp Lys Ala Pro Lys Ser Pro Val Gly Val 
            260                 265                 270         


Gln Pro Ile Leu Asn Glu His Thr Phe Cys Val Gly Met Ser Lys Tyr 
        275                 280                 285             


Gln Glu Asp Thr Cys Tyr Gly Asp Ala Gly Ser Ala Phe Ala Val His 
    290                 295                 300                 


Asp Leu Glu Glu Asp Thr Trp Tyr Ala Ala Gly Ile Leu Ser Phe Asp 
305                 310                 315                 320 


Lys Ser Cys Ala Val Ala Glu Tyr Gly Val Tyr Val Lys Val Thr Ser 
                325                 330                 335     


Ile Gln His Trp Val Gln Lys Thr Ile Ala Glu Asn 
            340                 345             


<210>  1544
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  1544

Thr Pro Leu Pro Pro Thr Ser Ala His Gly Asn Val Ala Glu Gly Glu 
1               5                   10                  15      


Thr Lys Pro Asp Pro Asp Val Thr Glu Arg Cys Ser Asp Gly Trp Ser 
            20                  25                  30          


Phe Asp Ala Thr Thr Leu Asp Asp Asn Gly Thr Met Leu Phe Phe Lys 
        35                  40                  45              


Gly Glu Phe Val Trp Lys Ser His Lys Trp Asp Arg Glu Leu Ile Ser 
    50                  55                  60                  


Glu Arg Trp Lys Asn Phe Pro Ser Pro Val Asp Ala Ala Phe Arg Gln 
65                  70                  75                  80  


Gly His Asn Ser Val Phe Leu Ile Lys Gly Asp Lys Val Trp Val Tyr 
                85                  90                  95      


Pro Pro Glu Lys Lys Glu Lys Gly Tyr Pro Lys Leu Leu Gln Asp Glu 
            100                 105                 110         


Phe Pro Gly Ile Pro Ser Pro Leu Asp Ala Ala Val Glu Cys His Arg 
        115                 120                 125             


Gly Glu Cys Gln Ala Glu Gly Val Leu Phe Phe Gln Gly Asp Arg Glu 
    130                 135                 140                 


Trp Phe Trp Asp Leu Ala Thr Gly Thr Met Lys Glu Arg Ser Trp Pro 
145                 150                 155                 160 


Ala Val Gly Asn Cys Ser Ser Ala Leu Arg Trp Leu Gly Arg Tyr Tyr 
                165                 170                 175     


Cys Phe Gln Gly Asn Gln Phe Leu Arg Phe Asp Pro Val Arg Gly Glu 
            180                 185                 190         


Val Pro Pro Arg Tyr Pro Arg Asp Val Arg Asp Tyr Phe Met Pro Cys 
        195                 200                 205             


Pro Gly Arg Gly His Gly His Arg Asn Gly Thr Gly His Gly Asn Ser 
    210                 215                 220                 


Thr His His Gly Pro Glu Tyr Met Arg Cys Ser Pro His Leu Val Leu 
225                 230                 235                 240 


Ser Ala Leu Thr Ser Asp Asn His Gly Ala Thr Tyr Ala Phe Ser Gly 
                245                 250                 255     


Thr His Tyr Trp Arg Leu Asp Thr Ser Arg Asp Gly Trp His Ser Trp 
            260                 265                 270         


Pro Ile Ala His Gln Trp Pro Gln Gly Pro Ser Ala Val Asp Ala Ala 
        275                 280                 285             


Phe Ser Trp Glu Glu Lys Leu Tyr Leu Val Gln Gly Thr Gln Val Tyr 
    290                 295                 300                 


Val Phe Leu Thr Lys Gly Gly Tyr Thr Leu Val Ser Gly Tyr Pro Lys 
305                 310                 315                 320 


Arg Leu Glu Lys Glu Val Gly Thr Pro His Gly Ile Ile Leu Asp Ser 
                325                 330                 335     


Val Asp Ala Ala Phe Ile Cys Pro Gly Ser Ser Arg Leu His Ile Met 
            340                 345                 350         


Ala Gly Arg Arg Leu Trp Trp Leu Asp Leu Lys Ser Gly Ala Gln Ala 
        355                 360                 365             


Thr Trp Thr Glu Leu Pro Trp Pro His Glu Lys Val Asp Gly Ala Leu 
    370                 375                 380                 


Cys Met Glu Lys Ser Leu Gly Pro Asn Ser Cys Ser Ala Asn Gly Pro 
385                 390                 395                 400 


Gly Leu Tyr Leu Ile His Gly Pro Asn Leu Tyr Cys Tyr Ser Asp Val 
                405                 410                 415     


Glu Lys Leu Asn Ala Ala Lys Ala Leu Pro Gln Pro Gln Asn Val Thr 
            420                 425                 430         


Ser Leu Leu Gly Cys Thr His 
        435                 


<210>  1545
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  1545

Tyr Tyr Trp Asp Asp Asn Phe Asp Pro Ala Ser Leu Gln Gly Ala Arg 
1               5                   10                  15      


Val Leu Leu Thr Gly Ala Asn Ala Gly Val Gly Glu Glu Leu Ala Tyr 
            20                  25                  30          


His Tyr Ala Arg Leu Gly Ser His Leu Val Leu Thr Ala His Thr Glu 
        35                  40                  45              


Ala Leu Leu Gln Lys Val Val Gly Asn Cys Arg Lys Leu Gly Ala Pro 
    50                  55                  60                  


Lys Val Phe Tyr Ile Ala Ala Asp Met Ala Ser Pro Glu Ala Pro Glu 
65                  70                  75                  80  


Ser Val Val Gln Phe Ala Leu Asp Lys Leu Gly Gly Leu Asp Tyr Leu 
                85                  90                  95      


Val Leu Asn His Ile Gly Gly Ala Pro Ala Gly Thr Arg Ala Arg Ser 
            100                 105                 110         


Pro Gln Ala Thr Arg Trp Leu Met Gln Val Asn Phe Val Ser Tyr Val 
        115                 120                 125             


Gln Leu Thr Ser Arg Ala Leu Pro Ser Leu Thr Asp Ser Lys Gly Ser 
    130                 135                 140                 


Leu Val Val Val Ser Ser Leu Leu Gly Arg Val Pro Thr Ser Phe Ser 
145                 150                 155                 160 


Thr Pro Tyr Ser Ala Ala Lys Phe Ala Leu Asp Gly Phe Phe Gly Ser 
                165                 170                 175     


Leu Arg Arg Glu Leu Asp Val Gln Asp Val Asn Val Ala Ile Thr Met 
            180                 185                 190         


Cys Val Leu Gly Leu Arg Asp Arg Ala Ser Ala Ala Glu Ala Val Arg 
        195                 200                 205             


Ser Ser Thr Ser Arg Pro Arg Gln Pro Glu His Arg Gly Val Pro Leu 
    210                 215                 220                 


Gln Ser Gln Thr Ala Met Phe Leu Pro Pro Thr Val Pro Gly Ala Arg 
225                 230                 235                 240 


Thr Leu Thr Glu Thr Pro Leu Arg Gly Trp Pro Gln Pro Lys Met Lys 
                245                 250                 255     


Ser Ser Arg Gln Lys Ser Lys Thr Glu Lys Asn Asp Gly His Leu Glu 
            260                 265                 270         


Pro Val Thr Ala Trp Glu Val Gln Val Pro Arg Val Arg Arg Leu Cys 
        275                 280                 285             


Arg Gly Leu Ala Arg Pro His Leu Phe Gly His Asp 
    290                 295                 300 


<210>  1546
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  1546

Asp Thr Leu Ile Ile Asn Cys Pro Gly Phe Gly Gln His Arg Val Asp 
1               5                   10                  15      


Pro Ala Ala Phe Gln Ala Val Phe Asp Arg Lys Ala Ile Gly Pro Val 
            20                  25                  30          


Thr Asn Tyr Ser Val Ala Thr His Val Asn Ile Ser Phe Thr Leu Ser 
        35                  40                  45              


Ala Ile Trp Asn Cys Tyr Ser Arg Ile His Thr Phe Asn Cys His His 
    50                  55                  60                  


Ala Arg Pro Trp His Asn Gln Phe Val Gln Trp Asn Pro Asp Glu Cys 
65                  70                  75                  80  


Gly Gly Ile Lys Lys Ser Gly Met Ala Thr Glu Asn Leu Trp Leu Ser 
                85                  90                  95      


Asp Val Phe Ile Glu Glu Ser Val Asp Gln Thr Pro Ala Gly Leu Met 
            100                 105                 110         


Ala Ser Met Ser Ile Val Lys Ala Thr Ser Asn Thr Ile Ser Gln Cys 
        115                 120                 125             


Gly Trp Ser Ala Ser Ala Asn Trp Thr Pro Ser Ile Ser Pro Ser Met 
    130                 135                 140                 


Asp Arg Ala Arg Ala Trp Arg Arg Met Ser Arg Ser Phe Gln Ile His 
145                 150                 155                 160 


His Arg Thr Ser Phe Arg Thr Arg Arg Glu Trp Val Leu Leu Gly Ile 
                165                 170                 175     


Gln Lys Arg Thr Ile Lys Val Thr Val Ala Thr Asn Gln Tyr Glu Gln 
            180                 185                 190         


Ala Ile Phe His Val Ala Ile Arg Arg Arg Cys Arg Pro Ser Pro Tyr 
        195                 200                 205             


<210>  1547
<211>  458
<212>  PRT
<213>  Homo Sapiens

<400>  1547

Gln Leu Ser Arg Ala Gly Arg Ser Ala Pro Leu Ala Ala Gly Cys Pro 
1               5                   10                  15      


Asp Arg Cys Glu Pro Ala Arg Cys Pro Pro Gln Pro Glu His Cys Glu 
            20                  25                  30          


Gly Gly Arg Ala Arg Asp Ala Cys Gly Cys Cys Glu Val Cys Gly Ala 
        35                  40                  45              


Pro Glu Gly Ala Ala Cys Gly Leu Gln Glu Gly Pro Cys Gly Glu Gly 
    50                  55                  60                  


Leu Gln Cys Val Val Pro Phe Gly Val Pro Ala Ser Ala Thr Val Arg 
65                  70                  75                  80  


Arg Arg Ala Gln Ala Gly Leu Cys Val Cys Ala Ser Ser Glu Pro Val 
                85                  90                  95      


Cys Gly Ser Asp Ala Asn Thr Tyr Ala Asn Leu Cys Gln Leu Arg Ala 
            100                 105                 110         


Ala Ser Arg Arg Ser Glu Arg Leu His Arg Pro Pro Val Ile Val Leu 
        115                 120                 125             


Gln Arg Gly Ala Cys Gly Gln Gly Gln Glu Asp Pro Asn Ser Leu Arg 
    130                 135                 140                 


His Lys Tyr Asn Phe Ile Ala Asp Val Val Glu Lys Ile Ala Pro Ala 
145                 150                 155                 160 


Val Val His Ile Glu Leu Phe Arg Lys Leu Pro Phe Ser Lys Arg Glu 
                165                 170                 175     


Val Pro Val Ala Ser Gly Ser Gly Phe Ile Val Ser Glu Asp Gly Leu 
            180                 185                 190         


Ile Val Thr Asn Ala His Val Val Thr Asn Lys His Arg Val Lys Val 
        195                 200                 205             


Glu Leu Lys Asn Gly Ala Thr Tyr Glu Ala Lys Ile Lys Asp Val Asp 
    210                 215                 220                 


Glu Lys Ala Asp Ile Ala Leu Ile Lys Ile Asp His Gln Gly Lys Leu 
225                 230                 235                 240 


Pro Val Leu Leu Leu Gly Arg Ser Ser Glu Leu Arg Pro Gly Glu Phe 
                245                 250                 255     


Val Val Ala Ile Gly Ser Pro Phe Ser Leu Gln Asn Thr Val Thr Thr 
            260                 265                 270         


Gly Ile Val Ser Thr Thr Gln Arg Gly Gly Lys Glu Leu Gly Leu Arg 
        275                 280                 285             


Asn Ser Asp Met Asp Tyr Ile Gln Thr Asp Ala Ile Ile Asn Tyr Gly 
    290                 295                 300                 


Asn Ser Gly Gly Pro Leu Val Asn Leu Asp Gly Glu Val Ile Gly Ile 
305                 310                 315                 320 


Asn Thr Leu Lys Val Thr Ala Gly Ile Ser Phe Ala Ile Pro Ser Asp 
                325                 330                 335     


Lys Ile Lys Lys Phe Leu Thr Glu Ser His Asp Arg Gln Ala Lys Gly 
            340                 345                 350         


Lys Ala Ile Thr Lys Lys Lys Tyr Ile Gly Ile Arg Met Met Ser Leu 
        355                 360                 365             


Thr Ser Ser Lys Ala Lys Glu Leu Lys Asp Arg His Arg Asp Phe Pro 
    370                 375                 380                 


Asp Val Ile Ser Gly Ala Tyr Ile Ile Glu Val Ile Pro Asp Thr Pro 
385                 390                 395                 400 


Ala Glu Ala Gly Gly Leu Lys Glu Asn Asp Val Ile Ile Ser Ile Asn 
                405                 410                 415     


Gly Gln Ser Val Val Ser Ala Asn Asp Val Ser Asp Val Ile Lys Arg 
            420                 425                 430         


Glu Ser Thr Leu Asn Met Val Val Arg Arg Gly Asn Glu Asp Ile Met 
        435                 440                 445             


Ile Thr Val Ile Pro Glu Glu Ile Asp Pro 
    450                 455             


<210>  1548
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  1548

Thr Asp Ala Leu Asn Val Leu Leu Ile Ile Val Asp Asp Leu Arg Pro 
1               5                   10                  15      


Ser Leu Gly Cys Tyr Gly Asp Lys Leu Val Arg Ser Pro Asn Ile Asp 
            20                  25                  30          


Gln Leu Ala Ser His Ser Leu Leu Phe Gln Asn Ala Phe Ala Gln Gln 
        35                  40                  45              


Ala Val Cys Ala Pro Ser Arg Val Ser Phe Leu Thr Gly Arg Arg Pro 
    50                  55                  60                  


Asp Thr Thr Arg Leu Tyr Asp Phe Asn Ser Tyr Trp Arg Val His Ala 
65                  70                  75                  80  


Gly Asn Phe Ser Thr Ile Pro Gln Tyr Phe Lys Glu Asn Gly Tyr Val 
                85                  90                  95      


Thr Met Ser Val Gly Lys Val Phe His Pro Gly Ile Ser Ser Asn His 
            100                 105                 110         


Thr Asp Asp Ser Pro Tyr Ser Trp Ser Phe Pro Pro Tyr His Pro Ser 
        115                 120                 125             


Ser Glu Lys Tyr Glu Asn Thr Lys Thr Cys Arg Gly Pro Asp Gly Glu 
    130                 135                 140                 


Leu His Ala Asn Leu Leu Cys Pro Val Asp Val Leu Asp Val Pro Glu 
145                 150                 155                 160 


Gly Thr Leu Pro Asp Lys Gln Ser Thr Glu Gln Ala Ile Gln Leu Leu 
                165                 170                 175     


Glu Lys Met Lys Thr Ser Ala Ser Pro Phe Phe Leu Ala Val Gly Tyr 
            180                 185                 190         


His Lys Pro His Ile Pro Phe Arg Tyr Pro Lys Glu Phe Gln Lys Leu 
        195                 200                 205             


Tyr Pro Leu Glu Asn Ile Thr Leu Ala Pro Asp Pro Glu Val Pro Asp 
    210                 215                 220                 


Gly Leu Pro Pro Val Ala Tyr Asn Pro Trp Met Asp Ile Arg Gln Arg 
225                 230                 235                 240 


Glu Asp Val Gln Ala Leu Asn Ile Ser Val Pro Tyr Gly Pro Ile Pro 
                245                 250                 255     


Val Asp Phe Gln Arg Lys Ile Arg Gln Ser Tyr Phe Ala Ser Val Ser 
            260                 265                 270         


Tyr Leu Asp Thr Gln Val Gly Arg Leu Leu Ser Ala Leu Asp Asp Leu 
        275                 280                 285             


Gln Leu Ala Asn Ser Thr Ile Ile Ala Phe Thr Ser Asp His Gly Trp 
    290                 295                 300                 


Ala Leu Gly Glu His Gly Glu Trp Ala Lys Tyr Ser Asn Phe Asp Val 
305                 310                 315                 320 


Ala Thr His Val Pro Leu Ile Phe Tyr Val Pro Gly Arg Thr Ala Ser 
                325                 330                 335     


Leu Pro Glu Ala Gly Glu Lys Leu Phe Pro Tyr Leu Asp Pro Phe Asp 
            340                 345                 350         


Ser Ala Ser Gln Leu Met Glu Pro Gly Arg Gln Ser Met Asp Leu Val 
        355                 360                 365             


Glu Leu Val Ser Leu Phe Pro Thr Leu Ala Gly Leu Ala Gly Leu Gln 
    370                 375                 380                 


Val Pro Pro Arg Cys Pro Val Pro Ser Phe His Val Glu Leu Cys Arg 
385                 390                 395                 400 


Glu Gly Lys Asn Leu Leu Lys His Phe Arg Phe Arg Asp Leu Glu Glu 
                405                 410                 415     


Asp Pro Tyr Leu Pro Gly Asn Pro Arg Glu Leu Ile Ala Tyr Ser Gln 
            420                 425                 430         


Tyr Pro Arg Pro Ser Asp Ile Pro Gln Trp Asn Ser Asp Lys Pro Ser 
        435                 440                 445             


Leu Lys Asp Ile Lys Ile Met Gly Tyr Ser Ile Arg Thr Ile Asp Tyr 
    450                 455                 460                 


Arg Tyr Thr Val Trp Val Gly Phe Asn Pro Asp Glu Phe Leu Ala Asn 
465                 470                 475                 480 


Phe Ser Asp Ile His Ala Gly Glu Leu Tyr Phe Val Asp Ser Asp Pro 
                485                 490                 495     


Leu Gln Asp His Asn Met Tyr Asn Asp Ser Gln Gly Gly Asp Leu Phe 
            500                 505                 510         


Gln Leu Leu Met Pro 
        515         


<210>  1549
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  1549

Gly Pro Glu Thr Leu Cys Gly Ala Glu Leu Val Asp Ala Leu Gln Phe 
1               5                   10                  15      


Val Cys Gly Asp Arg Gly Phe Tyr Phe Asn Lys Pro Thr Gly Tyr Gly 
            20                  25                  30          


Ser Ser Ser Arg Arg Ala Pro Gln Thr Gly Ile Val Asp Glu Cys Cys 
        35                  40                  45              


Phe Arg Ser Cys Asp Leu Arg Arg Leu Glu Met Tyr Cys Ala Pro Leu 
    50                  55                  60                  


Lys Pro Ala Lys Ser Ala 
65                  70  


<210>  1550
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  1550

Glu Gly Val Thr Asp Leu Arg Leu Trp Leu Cys Gln Pro Ala Pro Arg 
1               5                   10                  15      


Cys Gly Glu Trp Thr Tyr Asn Pro Leu Glu Gln Cys Cys Asp Asp Gly 
            20                  25                  30          


Val Ile Leu Asp Leu Asn Gln Thr Arg Leu Cys Gly Ser Ser Cys Thr 
        35                  40                  45              


Phe Trp Pro Cys Phe Gln His Cys Cys Leu Glu Ser Leu Gly Ser Gln 
    50                  55                  60                  


Asn Gln Thr Val Val Arg Phe Lys Val Pro Gly Met Lys Pro Asp Cys 
65                  70                  75                  80  


Lys Ser Ser Pro Ile Thr Arg Ile Cys Ala Gln Glu Tyr His Pro Lys 
                85                  90                  95      


Ser Pro Val Ser Arg Ser Asp Leu Ile 
            100                 105 


<210>  1551
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  1551

Cys Gly Pro Gly Arg Val Val Gly Ser Arg Arg Arg Pro Pro Arg Lys 
1               5                   10                  15      


Leu Val Pro Leu Ala Tyr Lys Gln Phe Ser Pro Asn Val Pro Glu Lys 
            20                  25                  30          


Thr Leu Gly Ala Ser Gly Arg Tyr Glu Gly Lys Ile Ala Arg Ser Ser 
        35                  40                  45              


Glu Arg Phe Lys Glu Leu Thr Pro Asn Tyr Asn Pro Asp Ile Ile Phe 
    50                  55                  60                  


Lys Asp Glu Glu Asn Thr Gly Ala Asp Arg Leu Met Thr Gln Arg Cys 
65                  70                  75                  80  


Lys Asp Arg Leu Asn Ser Leu Ala Ile Ser Val Met Asn Gln Trp Pro 
                85                  90                  95      


Gly Val Lys Leu Arg Val Thr Glu Gly Trp Asp Glu Asp Gly His His 
            100                 105                 110         


Ser Glu Glu Ser Leu His Tyr Glu Gly Arg Ala Val Asp Ile Thr Thr 
        115                 120                 125             


Ser Asp Arg Asp Arg Asn Lys Tyr Gly Leu Leu Ala Arg Leu Ala Val 
    130                 135                 140                 


Glu Ala Gly Phe Asp Trp Val Tyr Tyr Glu Ser Lys Ala His Val His 
145                 150                 155                 160 


Cys Ser Val Lys Ser Glu His Ser Ala Ala Ala Lys Thr Gly Gly 
                165                 170                 175 


<210>  1552
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  1552

Gly Leu Glu Cys Asp Gly Arg Thr Asn Leu Cys Cys Arg Gln Gln Phe 
1               5                   10                  15      


Phe Ile Asp Phe Arg Leu Ile Gly Trp Asn Asp Trp Ile Ile Ala Pro 
            20                  25                  30          


Thr Gly Tyr Tyr Gly Asn Tyr Cys Glu Gly Ser Cys Pro Ala Tyr Leu 
        35                  40                  45              


Ala Gly Val Pro Gly Ser Ala Ser Ser Phe His Thr Ala Val Val Asn 
    50                  55                  60                  


Gln Tyr Arg Met Arg Gly Leu Asn Pro Gly Thr Val Asn Ser Cys Cys 
65                  70                  75                  80  


Ile Pro Thr Lys Leu Ser Thr Met Ser Met Leu Tyr Phe Asp Asp Glu 
                85                  90                  95      


Tyr Asn Ile Val Lys Arg Asp Val Pro Asn Met Ile Val Glu Glu Cys 
            100                 105                 110         


Gly Cys Ala 
        115 


<210>  1553
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  1553

Ala Asp Gly Pro Asp Ala Ala Ala Gly Asn Ala Ser Gln Ala Gln Leu 
1               5                   10                  15      


Gln Asn Asn Leu Asn Val Gly Ser Asp Thr Thr Ser Glu Thr Ser Phe 
            20                  25                  30          


Ser Leu Ser Lys Glu Ala Pro Arg Glu His Leu Asp His Gln Ala Ala 
        35                  40                  45              


His Gln Pro Phe Pro Arg Pro Arg Phe Arg Gln Glu Thr Gly His Pro 
    50                  55                  60                  


Ser Leu Gln Arg Asp Phe Pro Arg Ser Phe Leu Leu Asp Leu Pro Asn 
65                  70                  75                  80  


Phe Pro Asp Leu Ser Lys Ala Asp Ile Asn Gly Gln Asn Pro Asn Ile 
                85                  90                  95      


Gln Val Thr Ile Glu Val Val Asp Gly Pro Asp Ser Glu Ala Asp Lys 
            100                 105                 110         


Asp Gln His Pro Glu Asn Lys Pro Ser Trp Ser Val Pro Ser Pro Asp 
        115                 120                 125             


Trp Arg Ala Trp Trp Gln Arg Ser Leu Ser Leu Ala Arg Ala Asn Ser 
    130                 135                 140                 


Gly Asp Gln Asp Tyr Lys Tyr Asp Ser Thr Ser Asp Asp Ser Asn Phe 
145                 150                 155                 160 


Leu Asn Pro Pro Arg Gly Trp Asp His Thr Ala Pro Gly His Arg Thr 
                165                 170                 175     


Phe Glu Thr Lys Asp Gln Pro Glu Tyr Asp Ser Thr Asp Gly Glu Gly 
            180                 185                 190         


Asp Trp Ser Leu Trp Ser Val Cys Ser Val Thr Cys Gly Asn Gly Asn 
        195                 200                 205             


Gln Lys Arg Thr Arg Ser Cys Gly Tyr Ala Cys Thr Ala Thr Glu Ser 
    210                 215                 220                 


Arg Thr Cys Asp Arg Pro Asn Cys Pro Gly Ile Glu Asp Thr Phe Arg 
225                 230                 235                 240 


Thr Ala Ala Thr Glu Val Ser Leu Leu Ala Gly Ser Glu Glu Phe Asn 
                245                 250                 255     


Ala Thr Lys Leu Phe Glu Val Asp Thr Asp Ser Cys Glu Arg Trp Met 
            260                 265                 270         


Ser Cys Lys Ser Glu Phe Leu Lys Lys Tyr Met His Lys Val Met Asn 
        275                 280                 285             


Asp Leu Pro Ser Cys Pro Cys Ser Tyr Pro Thr Glu Val Ala Tyr Ser 
    290                 295                 300                 


Thr Ala Asp Ile Phe Asp Arg Ile Lys Arg Lys Asp Phe Arg Trp Lys 
305                 310                 315                 320 


Asp Ala Ser Gly Pro Lys Glu Lys Leu Glu Ile Tyr Lys Pro Thr Ala 
                325                 330                 335     


Arg Tyr Cys Ile Arg Ser Met Leu Ser Leu Glu Ser Thr Thr Leu Ala 
            340                 345                 350         


Ala Gln His Cys Cys Tyr Gly Asp Asn Met Gln Leu Ile Thr Arg Gly 
        355                 360                 365             


Lys Gly Ala Gly Thr Pro Asn Leu Ile Ser Thr Glu Phe Ser Ala Glu 
    370                 375                 380                 


Leu His Tyr Lys Val Asp Val Leu Pro Trp Ile Ile Cys Lys Gly Asp 
385                 390                 395                 400 


Trp Ser Arg Tyr Asn Glu Ala Arg Pro Pro Asn Asn Gly Gln Lys Cys 
                405                 410                 415     


Thr Glu Ser Pro Ser Asp Glu Asp Tyr Ile Lys Gln Phe Gln Glu Ala 
            420                 425                 430         


Arg Glu Tyr 
        435 


<210>  1554
<211>  532
<212>  PRT
<213>  Homo Sapiens

<400>  1554

Ile Ile Asn His Pro Leu Leu Phe Pro Arg Glu Asn Ala Thr Val Pro 
1               5                   10                  15      


Glu Asn Glu Glu Glu Ile Ile Arg Lys Met Gln Ala His Gln Glu Lys 
            20                  25                  30          


Leu Gln Leu Glu Gln Leu Arg Leu Glu Glu Glu Val Ala Arg Leu Ala 
        35                  40                  45              


Ala Glu Lys Glu Ala Leu Glu Gln Val Ala Glu Glu Gly Arg Gln Gln 
    50                  55                  60                  


Asn Glu Thr Arg Val Ala Trp Asp Leu Trp Ser Thr Leu Cys Met Ile 
65                  70                  75                  80  


Leu Phe Leu Met Ile Glu Val Trp Arg Gln Asp His Gln Glu Gly Pro 
                85                  90                  95      


Ser Pro Glu Cys Leu Gly Gly Glu Glu Asp Glu Leu Pro Gly Leu Gly 
            100                 105                 110         


Gly Ala Pro Leu Gln Gly Leu Thr Leu Pro Asn Lys Ala Thr Leu Gly 
        115                 120                 125             


His Phe Tyr Glu Arg Cys Ile Arg Gly Ala Thr Ala Asp Ala Ala Arg 
    130                 135                 140                 


Thr Arg Glu Phe Leu Glu Gly Phe Val Asp Asp Leu Leu Glu Ala Leu 
145                 150                 155                 160 


Arg Ser Leu Cys Asn Arg Asp Thr Asp Met Glu Val Glu Asp Phe Ile 
                165                 170                 175     


Gly Val Asp Ser Met Tyr Glu Asn Trp Gln Val Asp Arg Pro Leu Leu 
            180                 185                 190         


Cys His Leu Phe Val Pro Phe Thr Pro Pro Glu Pro Tyr Arg Phe His 
        195                 200                 205             


Pro Glu Leu Trp Cys Ser Gly Arg Ser Val Pro Leu Asp Arg Gln Gly 
    210                 215                 220                 


Tyr Gly Gln Ile Lys Val Val Arg Ala Asp Gly Asp Thr Leu Ser Cys 
225                 230                 235                 240 


Ile Cys Gly Lys Thr Lys Leu Gly Glu Asp Met Leu Cys Leu Leu His 
                245                 250                 255     


Gly Arg Asn Ser Met Ala Pro Pro Cys Gly Asp Met Glu Asn Leu Leu 
            260                 265                 270         


Cys Ala Thr Asp Ser Leu Tyr Leu Asp Thr Met Gln Val Met Lys Trp 
        275                 280                 285             


Phe Gln Thr Ala Leu Thr Arg Ala Trp Lys Gly Ile Ala His Lys Tyr 
    290                 295                 300                 


Glu Phe Asp Leu Ala Phe Gly Gln Leu Asp Ser Pro Gly Ser Leu Lys 
305                 310                 315                 320 


Ile Lys Phe Arg Ser Gly Lys Phe Met Pro Phe Asn Leu Ile Pro Val 
                325                 330                 335     


Ile Gln Cys Asp Asp Ser Asp Leu Tyr Phe Val Ser His Leu Pro Arg 
            340                 345                 350         


Glu Pro Ser Glu Gly Thr Pro Ala Ser Ser Thr Asp Trp Leu Leu Ser 
        355                 360                 365             


Phe Ala Val Tyr Glu Arg His Phe Leu Arg Thr Thr Leu Lys Ala Leu 
    370                 375                 380                 


Pro Glu Gly Ala Cys His Leu Ser Cys Leu Gln Ile Ala Ser Phe Leu 
385                 390                 395                 400 


Leu Ser Lys Gln Ser Arg Leu Thr Gly Pro Ser Gly Leu Ser Ser Tyr 
                405                 410                 415     


His Leu Lys Thr Ala Leu Leu His Leu Leu Leu Leu Arg Gln Ala Ala 
            420                 425                 430         


Asp Trp Lys Ala Gly Gln Leu Asp Ala Arg Leu His Glu Leu Leu Cys 
        435                 440                 445             


Phe Leu Glu Lys Ser Leu Leu Gln Lys Lys Leu His His Phe Phe Ile 
    450                 455                 460                 


Gly Asn Arg Lys Val Pro Glu Ala Met Gly Leu Pro Glu Ala Val Leu 
465                 470                 475                 480 


Arg Ala Glu Pro Leu Asn Leu Phe Arg Pro Phe Val Leu Gln Arg Ser 
                485                 490                 495     


Leu Tyr Arg Lys Thr Leu Asp Ser Phe Tyr Glu Met Leu Lys Asn Ala 
            500                 505                 510         


Pro Ala Leu Ile Ser Glu Tyr Ser Leu His Val Pro Ser Asp Gln Pro 
        515                 520                 525             


Thr Pro Lys Ser 
    530         


<210>  1555
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  1555

His Pro Leu Met Val Ser Asp Arg Met Asp Leu Asp Thr Leu Ala Arg 
1               5                   10                  15      


Ser Arg Gln Leu Glu Lys Arg Met Ser Glu Glu Met Arg Leu Leu Glu 
            20                  25                  30          


Met Glu Phe Glu Glu Arg Lys Arg Ala Ala Glu Gln Arg Gln Lys Ala 
        35                  40                  45              


Glu Asn Phe Trp Thr Gly Asp Thr Ser Ser Asp Gln Leu Val Leu Gly 
    50                  55                  60                  


Lys Lys Asp Met Gly Trp Pro Phe Gln Ala Asp Gly Gln Glu Gly 
65                  70                  75                  


<210>  1556
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  1556

Asp Arg Ser Met Glu Lys Lys Lys Gly Glu Pro Arg Thr Arg Ala Glu 
1               5                   10                  15      


Ala Arg Pro Trp Val Asp Glu Asp Leu Lys Asp Ser Ser Asp Leu His 
            20                  25                  30          


Gln Ala Glu Glu Asp Ala Asp Glu Trp Gln Glu Ser Glu Glu Asn Val 
        35                  40                  45              


Glu His Ile Pro Phe Ser His Asn His Tyr Pro Glu Lys Glu Met Val 
    50                  55                  60                  


Lys Arg Ser Gln Glu Phe Tyr Glu Leu Leu Asn Lys Arg Arg Ser Val 
65                  70                  75                  80  


Arg Phe Ile Ser Asn Glu Gln Val Pro Met Glu Val Ile Asp Asn Val 
                85                  90                  95      


Ile Arg Thr Ala Gly Thr Ala Pro Ser Gly Ala His Thr Glu Pro Trp 
            100                 105                 110         


Thr Phe Val Val Val Lys Asp Pro Asp Val Lys His Lys Ile Arg Lys 
        115                 120                 125             


Ile Ile Glu Glu Glu Glu Glu Ile Asn Tyr Met Lys Arg Met Gly His 
    130                 135                 140                 


Arg Trp Val Thr Asp Leu Lys Lys Leu Arg Thr Asn Trp Ile Lys Glu 
145                 150                 155                 160 


Tyr Leu Asp Thr Ala Pro Ile Leu Ile Leu Ile Phe Lys Gln Val His 
                165                 170                 175     


Gly Phe Ala Ala Asn Gly Lys Lys Lys Val His Tyr Tyr Asn Glu 
            180                 185                 190     


<210>  1557
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  1557

Gly Asp Glu Leu Leu Asn Ile Cys Met Asn Ala Lys His His Lys Arg 
1               5                   10                  15      


Val Pro Ser Pro Glu Asp Lys Leu Tyr Glu Glu Cys Ile Pro Trp Lys 
            20                  25                  30          


Asp Asn Ala Cys Cys Thr Leu Thr Thr Ser Trp Glu Ala His Leu Asp 
        35                  40                  45              


Val Ser Pro Leu Tyr Asn Phe Ser Leu Phe His Cys Gly Leu Leu Met 
    50                  55                  60                  


Pro Gly Cys Arg Lys His Phe Ile Gln Ala Ile Cys Phe Tyr Glu Cys 
65                  70                  75                  80  


Ser Pro Asn Leu Gly Pro Trp Ile Gln Pro Val Gly Ser Leu Gly Trp 
                85                  90                  95      


Glu Val Ala Pro Ser Gly Gln Gly Glu Arg Val Val Asn Val Pro Leu 
            100                 105                 110         


Cys Gln Glu Asp Cys Glu Glu Trp Trp Glu Asp Cys Arg Met Ser Tyr 
        115                 120                 125             


Thr Cys Lys Ser Asn Trp Arg Gly Gly Trp Asp Trp Ser Gln Gly Lys 
    130                 135                 140                 


Asn Arg Cys Pro Lys Gly Ala Gln Cys Leu Pro Phe Ser His Tyr Phe 
145                 150                 155                 160 


Pro Thr Pro Ala Asp Leu Cys Glu Lys Thr Trp Ser Asn Ser Phe Lys 
                165                 170                 175     


Ala Ser Pro Glu Arg Arg Asn Ser Gly Arg Cys Leu Gln Lys Trp Phe 
            180                 185                 190         


Glu Pro Ala Gln Gly Asn Pro Asn Val Ala Val Ala Arg Leu Phe Ala 
        195                 200                 205             


Ser 
    


<210>  1558
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  1558

Cys Leu Gln Cys Asp Pro Leu Val Leu Glu Ala Leu Gly His Leu Arg 
1               5                   10                  15      


Ser Ala Leu Ile Pro Ser Arg Phe Gln Leu Glu Gln Leu Gln Ala Arg 
            20                  25                  30          


Ala Gly Ala Val Leu Met Gly Met Glu Gly Pro Phe Phe Arg Asp Tyr 
        35                  40                  45              


Ala Leu Asn Val Phe Val Gly Lys Val Glu Thr Asn Gln Leu Asp Leu 
    50                  55                  60                  


Val Ala Ser Phe Val Lys Asn Gln Thr Gln His Leu Met Gly Asn Ser 
65                  70                  75                  80  


Leu Lys Asp Glu Pro Leu Leu Glu Glu Leu Val Thr Leu Arg Ala Asn 
                85                  90                  95      


Val Ile Lys Glu Phe Lys Lys Val Leu Ile Ser Tyr Glu Leu Lys Ala 
            100                 105                 110         


Cys Asn Pro Lys Leu Cys Arg Leu Leu Lys Glu Glu Val Leu Asp Cys 
        115                 120                 125             


Leu His Cys Gln Arg Ile Thr Pro Lys Cys Ile His Lys Lys Tyr Cys 
    130                 135                 140                 


Phe Val Asp Arg Gln Pro Arg Val Ala Leu Gln Tyr Gln Met Asp Ser 
145                 150                 155                 160 


Lys Tyr Pro Arg Asn Gln 
                165     


<210>  1559
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  1559

Cys Leu Glu Cys Asp Pro Lys Phe Ile Glu Asp Val Gly Ser Leu Leu 
1               5                   10                  15      


Gly Asn Leu Ile Pro Ser Glu Val Pro Gly Arg Thr Gln Leu Leu Glu 
            20                  25                  30          


Arg Gln Ile Lys Glu Met Ile His Leu Ser Phe Lys Val Ser His Ser 
        35                  40                  45              


Asp Lys Arg Leu Arg Val Leu Ala Val Gln Gln Val Val Lys Leu Arg 
    50                  55                  60                  


Thr Trp Leu Lys Asn Glu Phe Tyr Lys Leu Gly Asn Glu Thr Trp Lys 
65                  70                  75                  80  


Gly Val Phe Ile Tyr Gln Gly Lys Leu Leu Asp Val Cys Gln Asn Leu 
                85                  90                  95      


Glu Ser Lys Leu Lys Glu Leu Leu Lys Asn Phe Ser Glu Ile Ala Cys 
            100                 105                 110         


Ser Glu Asp Cys Ile Val Val Glu Gly Pro Ile Leu Asp Cys Trp Thr 
        115                 120                 125             


Cys Leu Arg Met Thr Asn Arg Cys Phe Lys Gly Glu Tyr Cys Gly Asp 
    130                 135                 140                 


Glu Asp Pro Arg Lys Ala Glu Asn Arg Glu 
145                 150                 


<210>  1560
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1560

Glu Thr Leu Pro Gln Phe Arg Val Asp Gly Arg Gly Gly Asn Asn Gly 
1               5                   10                  15      


Gly Val Ser Arg Val Ser Pro Val Ser Arg Gly Ser Gln Glu Glu Glu 
            20                  25                  30          


Glu Asp Glu Asp Asp Ser Tyr Thr Phe His His Gly Ile Thr Pro Gly 
        35                  40                  45              


Glu Met Gly Thr Gly Gly Ser Ser Ser Leu Ser Thr Leu Gly Gly Ser 
    50                  55                  60                  


Phe Phe Thr Asp Pro 
65                  


<210>  1561
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  1561

Met His Phe Leu Thr Ile Tyr Pro Asn Cys Ser Ser Gly Val Val Arg 
1               5                   10                  15      


Ala Gln Ser Arg Thr Glu Gln Lys Asn Pro Leu Gly Leu Asp Asp Leu 
            20                  25                  30          


Gly Ile Gln Asn Leu Gly Gln Thr Val Ser Leu Ala Pro Ala Val Glu 
        35                  40                  45              


Ala Ala Ser Met Leu Lys Met Glu Pro Leu Asn Ser Thr His Pro Gly 
    50                  55                  60                  


Thr Ala Ala Ser Ser Ser Pro Leu Glu Ser Arg Ala Ala Gly Gly Gly 
65                  70                  75                  80  


Ser Gly Asn Gly Asn Glu 
                85      


<210>  1562
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  1562

Pro Leu Tyr Gln Lys Ser Val Trp Thr Gln Glu Ser Lys Cys His Leu 
1               5                   10                  15      


Ile Glu Thr Asn Ile Arg Asp Gln Glu Glu Leu Lys Gly Lys Lys Val 
            20                  25                  30          


Pro Gln Tyr Pro Cys Leu Trp Val Asn Val Ser Ala Ala Gly Arg Trp 
        35                  40                  45              


Ala Val Leu Tyr His Thr Glu Asp Thr Arg Asp Gln Asn Gln Gln Cys 
    50                  55                  60                  


Ser Tyr Ile Pro Gly Ser Val Asp Asn Tyr Gln Thr Ala Arg Ala Asp 
65                  70                  75                  80  


Val Glu Lys Val Arg Ala Lys Phe Gln Glu Gln Gln Val Phe Tyr Cys 
                85                  90                  95      


Phe Ser Ala Pro Arg Gly Asn Glu Thr Ser Val Leu Phe Gln Arg Leu 
            100                 105                 110         


Tyr Gly Pro Gln Ala Leu 
        115             


<210>  1563
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  1563

Ile Ile Lys Gly Phe Glu Cys Lys Pro His Ser Gln Pro Trp Gln Ala 
1               5                   10                  15      


Ala Leu Phe Glu Lys Thr Arg Leu Leu Cys Gly Ala Thr Leu Ile Ala 
            20                  25                  30          


Pro Arg Trp Leu Leu Thr Ala Ala His Cys Leu Lys Pro Arg Tyr Ile 
        35                  40                  45              


Val His Leu Gly Gln His Asn Leu Gln Lys Glu Glu Gly Cys Glu Gln 
    50                  55                  60                  


Thr Arg Thr Ala Thr Glu Ser Phe Pro His Pro Gly Phe Asn Asn Ser 
65                  70                  75                  80  


Leu Pro Asn Lys Asp His Arg Asn Asp Ile Met Leu Val Lys Met Ala 
                85                  90                  95      


Ser Pro Val Ser Ile Thr Trp Ala Val Arg Pro Leu Thr Leu Ser Ser 
            100                 105                 110         


Arg Cys Val Thr Ala Gly Thr Ser Cys Leu Ile Ser Gly Trp Gly Ser 
        115                 120                 125             


Thr Ser Ser Pro Gln Leu Arg Leu Pro His Thr Leu Arg Cys Ala Asn 
    130                 135                 140                 


Ile Thr Ile Ile Glu His Gln Lys Cys Glu Asn Ala Tyr Pro Gly Asn 
145                 150                 155                 160 


Ile Thr Asp Thr Met Val Cys Ala Ser Val Gln Glu Gly Gly Lys Asp 
                165                 170                 175     


Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Asn Gln Ser Leu 
            180                 185                 190         


Gln Gly Ile Ile Ser Trp Gly Gln Asp Pro Cys Ala Ile Thr Arg Lys 
        195                 200                 205             


Pro Gly Val Tyr Thr Lys Val Cys Lys Tyr Val Asp Trp Ile Gln Glu 
    210                 215                 220                 


Thr Met Lys Asn Asn 
225                 


<210>  1564
<211>  231
<212>  PRT
<213>  Homo Sapiens

<400>  1564

Ala Thr Pro Lys Ile Phe Asn Gly Thr Glu Cys Gly Arg Asn Ser Gln 
1               5                   10                  15      


Pro Trp Gln Val Gly Leu Phe Glu Gly Thr Ser Leu Arg Cys Gly Gly 
            20                  25                  30          


Val Leu Ile Asp His Arg Trp Val Leu Thr Ala Ala His Cys Ser Gly 
        35                  40                  45              


Ser Arg Tyr Trp Val Arg Leu Gly Glu His Ser Leu Ser Gln Leu Asp 
    50                  55                  60                  


Trp Thr Glu Gln Ile Arg His Ser Gly Phe Ser Val Thr His Pro Gly 
65                  70                  75                  80  


Tyr Leu Gly Ala Ser Thr Ser His Glu His Asp Leu Arg Leu Leu Arg 
                85                  90                  95      


Leu Arg Leu Pro Val Arg Val Thr Ser Ser Val Gln Pro Leu Pro Leu 
            100                 105                 110         


Pro Asn Asp Cys Ala Thr Ala Gly Thr Glu Cys His Val Ser Gly Trp 
        115                 120                 125             


Gly Ile Thr Asn His Pro Arg Asn Pro Phe Pro Asp Leu Leu Gln Cys 
    130                 135                 140                 


Leu Asn Leu Ser Ile Val Ser His Ala Thr Cys His Gly Val Tyr Pro 
145                 150                 155                 160 


Gly Arg Ile Thr Ser Asn Met Val Cys Ala Gly Gly Val Pro Gly Gln 
                165                 170                 175     


Asp Ala Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Gly Gly Val 
            180                 185                 190         


Leu Gln Gly Leu Val Ser Trp Gly Ser Val Gly Pro Cys Gly Gln Asp 
        195                 200                 205             


Gly Ile Pro Gly Val Tyr Thr Tyr Ile Cys Lys Tyr Val Asp Trp Ile 
    210                 215                 220                 


Arg Met Ile Met Arg Asn Asn 
225                 230     


<210>  1565
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  1565

Val Leu Gly Gly His Glu Cys Gln Pro His Ser Gln Pro Trp Gln Ala 
1               5                   10                  15      


Ala Leu Phe Gln Gly Gln Gln Leu Leu Cys Gly Gly Val Leu Val Gly 
            20                  25                  30          


Gly Asn Trp Val Leu Thr Ala Ala His Cys Lys Lys Pro Lys Tyr Thr 
        35                  40                  45              


Val Arg Leu Gly Asp His Ser Leu Gln Asn Lys Asp Gly Pro Glu Gln 
    50                  55                  60                  


Glu Ile Pro Val Val Gln Ser Ile Pro His Pro Cys Tyr Asn Ser Ser 
65                  70                  75                  80  


Asp Val Glu Asp His Asn His Asp Leu Met Leu Leu Gln Leu Arg Asp 
                85                  90                  95      


Gln Ala Ser Leu Gly Ser Lys Val Lys Pro Ile Ser Leu Ala Asp His 
            100                 105                 110         


Cys Thr Gln Pro Gly Gln Lys Cys Thr Val Ser Gly Trp Gly Thr Val 
        115                 120                 125             


Thr Ser Pro Arg Glu Asn Phe Pro Asp Thr Leu Asn Cys Ala Glu Val 
    130                 135                 140                 


Lys Ile Phe Pro Gln Lys Lys Cys Glu Asp Ala Tyr Pro Gly Gln Ile 
145                 150                 155                 160 


Thr Asp Gly Met Val Cys Ala Gly Ser Ser Lys Gly Ala Asp Thr Cys 
                165                 170                 175     


Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Asp Gly Ala Leu Gln Gly 
            180                 185                 190         


Ile Thr Ser Trp Gly Ser Asp Pro Cys Gly Arg Ser Asp Lys Pro Gly 
        195                 200                 205             


Val Tyr Thr Asn Ile Cys Arg Tyr Leu Asp Trp Ile Lys Lys Ile Ile 
    210                 215                 220                 


Gly Ser Lys Gly 
225             


<210>  1566
<211>  339
<212>  PRT
<213>  Homo Sapiens

<400>  1566

Gly Ser Leu His Ser Pro Gly Leu Ser Glu Cys Phe Gln Val Asn Gly 
1               5                   10                  15      


Ala Asp Tyr Arg Gly His Gln Asn Arg Thr Gly Pro Arg Gly Ala Gly 
            20                  25                  30          


Arg Pro Cys Leu Phe Trp Asp Gln Thr Gln Gln His Ser Tyr Ser Ser 
        35                  40                  45              


Ala Ser Asp Pro His Gly Arg Trp Gly Leu Gly Ala His Asn Phe Cys 
    50                  55                  60                  


Arg Asn Pro Asp Gly Asp Val Gln Pro Trp Cys Tyr Val Ala Glu Thr 
65                  70                  75                  80  


Glu Glu Gly Ile Tyr Trp Arg Tyr Cys Asp Ile Pro Ser Cys His Met 
                85                  90                  95      


Pro Gly Tyr Leu Gly Cys Phe Val Asp Ser Gly Ala Pro Pro Ala Leu 
            100                 105                 110         


Ser Gly Pro Ser Gly Thr Ser Thr Lys Leu Thr Val Gln Val Cys Leu 
        115                 120                 125             


Arg Phe Cys Arg Met Lys Gly Tyr Gln Leu Ala Gly Val Glu Ala Gly 
    130                 135                 140                 


Tyr Ala Cys Phe Cys Gly Ser Glu Ser Asp Leu Ala Arg Gly Arg Leu 
145                 150                 155                 160 


Ala Pro Ala Thr Asp Cys Asp Gln Ile Cys Phe Gly His Pro Gly Gln 
                165                 170                 175     


Leu Cys Gly Gly Asp Gly Arg Leu Gly Val Tyr Glu Val Ser Val Gly 
            180                 185                 190         


Ser Cys Gln Gly Asn Trp Thr Ala Pro Gln Gly Val Ile Tyr Ser Pro 
        195                 200                 205             


Asp Phe Pro Asp Glu Tyr Gly Pro Asp Arg Asn Cys Ser Trp Ala Leu 
    210                 215                 220                 


Gly Pro Pro Gly Ala Ala Leu Glu Leu Thr Phe Arg Leu Phe Glu Leu 
225                 230                 235                 240 


Ala Asp Pro Arg Asp Arg Leu Glu Leu Arg Asp Ala Ala Ser Gly Ser 
                245                 250                 255     


Leu Leu Arg Ala Phe Asp Gly Ala Arg Pro Pro Pro Ser Gly Pro Leu 
            260                 265                 270         


Arg Leu Gly Thr Ala Ala Leu Leu Leu Thr Phe Arg Ser Asp Ala Arg 
        275                 280                 285             


Gly His Ala Gln Gly Phe Ala Leu Thr Tyr Arg Gly Leu Gln Asp Ala 
    290                 295                 300                 


Ala Glu Asp Pro Glu Ala Pro Glu Gly Ser Ala Gln Thr Pro Ala Ala 
305                 310                 315                 320 


Pro Leu Asp Gly Ala Asn Val Ser Cys Ser Pro Arg Pro Gly Ala Pro 
                325                 330                 335     


Pro Ala Ala 
            


<210>  1567
<211>  341
<212>  PRT
<213>  Homo Sapiens

<400>  1567

Ser Asn Ser Asp Gly Ser Phe His Tyr Lys Asp Lys Leu Tyr Arg Ser 
1               5                   10                  15      


Ala Ser Gln Ala Leu Gln Ala Tyr Ile Asp Asp Phe Asp Leu Gly Gln 
            20                  25                  30          


Ile Tyr Pro Gly Ala Ser Thr Gly Lys Ile Asn Ile Asp Glu Asp Phe 
        35                  40                  45              


Thr Asn Met Ser Gln Phe Cys Asn Tyr Ile Tyr Lys Pro Asn Asn Ala 
    50                  55                  60                  


Phe Glu Asn Leu Asp His Lys Lys His Ser Asn Phe Ile Ser Cys Arg 
65                  70                  75                  80  


Arg His Thr Val Asn Asp Ile Asp Ser Met Ser Leu Thr Thr Asp Asp 
                85                  90                  95      


Leu Leu Arg Leu Pro Ala Asp Gly Ser Phe Ser Tyr Thr Tyr Val Gly 
            100                 105                 110         


Pro Ser His Arg Thr Ser Lys Lys Asn Lys Lys Cys Arg Gly Arg Leu 
        115                 120                 125             


Gly Ser Leu Asp Ile Glu Lys Asn Pro His Phe Gln Gly Pro Tyr Thr 
    130                 135                 140                 


Ser Met Gly Lys Asp Asn Phe Val Thr Pro Val Ile Arg Ser Asn Ile 
145                 150                 155                 160 


Asn Gly Lys Gln Cys Gly Asp Lys Ile Glu Leu Leu Ile Leu Lys Ala 
                165                 170                 175     


Lys Arg Asn Leu Glu Gln Cys Thr Glu Glu Leu Pro Lys Ser Met Lys 
            180                 185                 190         


Lys Asp Asp Ser Pro Cys Ser Leu Asp Lys Leu Glu Ala Asp Arg Ser 
        195                 200                 205             


Trp Glu Asn Ile Pro Val Thr Phe Lys Ser Pro Val Pro Val Asn Ser 
    210                 215                 220                 


Asp Asp Ser Pro Gln Gln Thr Ser Arg Ala Lys Ser Ala Lys Gly Val 
225                 230                 235                 240 


Leu Glu Asp Phe Leu Asn Asn Asp Asn Gln Ser Cys Thr Leu Ser Gly 
                245                 250                 255     


Gly Lys His His Gly Pro Val Glu Ala Leu Lys Gln Met Leu Phe Asn 
            260                 265                 270         


Leu Gln Ala Val Gln Glu Arg Phe Asn Gln Asn Lys Thr Thr Asp Pro 
        275                 280                 285             


Lys Glu Glu Ile Lys Gln Val Ser Glu Asp Asp Phe Ser Lys Leu Gln 
    290                 295                 300                 


Leu Lys Glu Ser Met Ile Pro Ile Thr Arg Ser Leu Gln Lys Ala Leu 
305                 310                 315                 320 


His His Leu Ser Arg Leu Arg Asp Leu Val Asp Asp Thr Asn Gly Glu 
                325                 330                 335     


Arg Ser Pro Lys Met 
            340     


<210>  1568
<211>  416
<212>  PRT
<213>  Homo Sapiens

<400>  1568

Phe Trp Leu Leu Asn Val Leu Phe Pro Pro His Thr Thr Pro Lys Ala 
1               5                   10                  15      


Glu Leu Ser Asn His Thr Arg Pro Val Ile Leu Val Pro Gly Cys Leu 
            20                  25                  30          


Gly Asn Gln Leu Glu Ala Lys Leu Asp Lys Pro Asp Val Val Asn Trp 
        35                  40                  45              


Met Cys Tyr Arg Lys Thr Glu Asp Phe Phe Thr Ile Trp Leu Asp Leu 
    50                  55                  60                  


Asn Met Phe Leu Pro Leu Gly Val Asp Cys Trp Ile Asp Asn Thr Arg 
65                  70                  75                  80  


Val Val Tyr Asn Arg Ser Ser Gly Leu Val Ser Asn Ala Pro Gly Val 
                85                  90                  95      


Gln Ile Arg Val Pro Gly Phe Gly Lys Thr Tyr Ser Val Glu Tyr Leu 
            100                 105                 110         


Asp Ser Ser Lys Leu Ala Gly Tyr Leu His Thr Leu Val Gln Asn Leu 
        115                 120                 125             


Val Asn Asn Gly Tyr Val Arg Asp Glu Thr Val Arg Ala Ala Pro Tyr 
    130                 135                 140                 


Asp Trp Arg Leu Glu Pro Gly Gln Gln Glu Glu Tyr Tyr Arg Lys Leu 
145                 150                 155                 160 


Ala Gly Leu Val Glu Glu Met His Ala Ala Tyr Gly Lys Pro Val Phe 
                165                 170                 175     


Leu Ile Gly His Ser Leu Gly Cys Leu His Leu Leu Tyr Phe Leu Leu 
            180                 185                 190         


Arg Gln Pro Gln Ala Trp Lys Asp Arg Phe Ile Asp Gly Phe Ile Ser 
        195                 200                 205             


Leu Gly Ala Pro Trp Gly Gly Ser Ile Lys Pro Met Leu Val Leu Ala 
    210                 215                 220                 


Ser Gly Asp Asn Gln Gly Ile Pro Ile Met Ser Ser Ile Lys Leu Lys 
225                 230                 235                 240 


Glu Glu Gln Arg Ile Thr Thr Thr Ser Pro Trp Met Phe Pro Ser Arg 
                245                 250                 255     


Met Ala Trp Pro Glu Asp His Val Phe Ile Ser Thr Pro Ser Phe Asn 
            260                 265                 270         


Tyr Thr Gly Arg Asp Phe Gln Arg Phe Phe Ala Asp Leu His Phe Glu 
        275                 280                 285             


Glu Gly Trp Tyr Met Trp Leu Gln Ser Arg Asp Leu Leu Ala Gly Leu 
    290                 295                 300                 


Pro Ala Pro Gly Val Glu Val Tyr Cys Leu Tyr Gly Val Gly Leu Pro 
305                 310                 315                 320 


Thr Pro Arg Thr Tyr Ile Tyr Asp His Gly Phe Pro Tyr Thr Asp Pro 
                325                 330                 335     


Val Gly Val Leu Tyr Glu Asp Gly Asp Asp Thr Val Ala Thr Arg Ser 
            340                 345                 350         


Thr Glu Leu Cys Gly Leu Trp Gln Gly Arg Gln Pro Gln Pro Val His 
        355                 360                 365             


Leu Leu Pro Leu His Gly Ile Gln His Leu Asn Met Val Phe Ser Asn 
    370                 375                 380                 


Leu Thr Leu Glu His Ile Asn Ala Ile Leu Leu Gly Ala Tyr Arg Gln 
385                 390                 395                 400 


Gly Pro Pro Ala Ser Pro Thr Ala Ser Pro Glu Pro Pro Pro Pro Glu 
                405                 410                 415     


<210>  1569
<211>  158
<212>  PRT
<213>  Homo Sapiens

<400>  1569

His His Leu Leu Ala Ser Asp Glu Glu Ile Gln Asp Val Ser Gly Thr 
1               5                   10                  15      


Trp Tyr Leu Lys Ala Met Thr Val Asp Arg Glu Phe Pro Glu Met Asn 
            20                  25                  30          


Leu Glu Ser Val Thr Pro Met Thr Leu Thr Thr Leu Glu Gly Gly Asn 
        35                  40                  45              


Leu Glu Ala Lys Val Thr Met Leu Ile Ser Gly Arg Cys Gln Glu Val 
    50                  55                  60                  


Lys Ala Val Leu Glu Lys Thr Asp Glu Pro Gly Lys Tyr Thr Ala Asp 
65                  70                  75                  80  


Gly Gly Lys His Val Ala Tyr Ile Ile Arg Ser His Val Lys Asp His 
                85                  90                  95      


Tyr Ile Phe Tyr Cys Glu Gly Glu Leu His Gly Lys Pro Val Arg Gly 
            100                 105                 110         


Val Lys Leu Val Gly Arg Asp Pro Lys Asn Asn Leu Glu Ala Leu Glu 
        115                 120                 125             


Asp Phe Glu Lys Ala Ala Gly Ala Arg Gly Leu Ser Thr Glu Ser Ile 
    130                 135                 140                 


Leu Ile Pro Arg Gln Ser Glu Thr Cys Ser Pro Gly Ser Asp 
145                 150                 155             


<210>  1570
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  1570

Ala Gly Ser Gln Val Gln Glu Trp Tyr Pro Arg Glu Ser His Ala Leu 
1               5                   10                  15      


Asn Trp Asn Lys Phe Ser Gly Phe Trp Tyr Ile Leu Ala Thr Ala Thr 
            20                  25                  30          


Asp Ala Gln Gly Phe Leu Pro Ala Arg Asp Lys Arg Lys Leu Gly Ala 
        35                  40                  45              


Ser Val Val Lys Val Asn Lys Val Gly Gln Leu Arg Val Leu Leu Ala 
    50                  55                  60                  


Phe Arg Arg Gly Gln Gly Cys Gly Arg Ala Gln Pro Arg His Pro Gly 
65                  70                  75                  80  


Thr Ser Gly His Leu Trp Ala Ser Leu Ser Val Lys Gly Val Lys Ala 
                85                  90                  95      


Phe His Val Leu Ser Thr Asp Tyr Ser Tyr Gly Leu Val Tyr Leu Arg 
            100                 105                 110         


Leu Gly Arg Ala Thr Gln Asn Tyr Lys Asn Leu Leu Leu Phe His Arg 
        115                 120                 125             


Gln Asn Val Ser Ser Phe Gln Ser Leu Lys Glu Phe Met Asp Ala Cys 
    130                 135                 140                 


Asp Ile Leu Gly Leu Ser Lys Ala Ala Val Ile Leu Pro Lys Asp Ala 
145                 150                 155                 160 


Ser Arg Thr His Thr Ile Leu Pro 
                165             


<210>  1571
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  1571

Gln Thr Pro Thr Pro Leu Pro Leu Pro Pro Pro Met Gln Ser Phe Gln 
1               5                   10                  15      


Gly Asn Gln Phe Gln Gly Glu Trp Phe Val Leu Gly Leu Ala Gly Asn 
            20                  25                  30          


Ser Phe Arg Pro Glu His Arg Ala Leu Leu Asn Ala Phe Thr Ala Thr 
        35                  40                  45              


Phe Glu Leu Ser Asp Asp Gly Arg Phe Glu Val Trp Asn Ala Met Thr 
    50                  55                  60                  


Arg Gly Gln His Cys Asp Thr Trp Ser Tyr Val Leu Ile Pro Ala Ala 
65                  70                  75                  80  


Gln Pro Gly Gln Phe Thr Val Asp His Gly Val Glu Pro Gly Ala Asp 
                85                  90                  95      


Arg Glu Glu Thr Arg Val Val Asp Ser Asp Tyr Thr Gln Phe Ala Leu 
            100                 105                 110         


Met Leu Ser Arg Arg His Thr Ser Arg Leu Ala Val Leu Arg Ile Ser 
        115                 120                 125             


Leu Leu Gly Arg Ser Trp Leu Leu Pro Pro Gly Thr Leu Asp Gln Phe 
    130                 135                 140                 


Ile Cys Leu Gly Arg Ala Gln Gly Leu Ser Asp Asp Asn Ile Val Phe 
145                 150                 155                 160 


Pro Asp Val Thr Gly Trp Ser Pro Gln Ala Ser Val Cys 
                165                 170             


<210>  1572
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  1572

His His Leu Leu Ala Ser Asp Glu Glu Ile Gln Asp Val Ser Gly Thr 
1               5                   10                  15      


Trp Tyr Leu Lys Ala Met Thr Val Asp Arg Glu Leu Pro Glu Met Asn 
            20                  25                  30          


Leu Glu Ser Val Thr Pro Met Thr Leu Thr Ile Leu Glu Gly Gly Asn 
        35                  40                  45              


Leu Glu Ala Lys Ala Thr Met Leu Ile Ser Gly Gln Cys Gln Glu Val 
    50                  55                  60                  


Lys Val Ile Leu Glu Lys Thr Asp Glu Pro Gly Lys Tyr Thr Ala Asn 
65                  70                  75                  80  


Arg Gly Lys His Val Ala Tyr Ile Ile Arg Ser His Met Lys Asp His 
                85                  90                  95      


Tyr Ile Phe Tyr Cys Glu Gly Arg Asp Pro Glu Asn Asn Leu Glu Ala 
            100                 105                 110         


Leu Glu Asp Phe Glu Lys Ala Ala Gly Ala Arg Gly Leu Ser Thr Glu 
        115                 120                 125             


Ser Ile Leu Ile Pro Arg Gln Ser Glu Thr Cys Ser Pro Gly Ser Asp 
    130                 135                 140                 


<210>  1573
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  1573

Leu Glu Thr Ala Asp Leu Ala Glu Leu Cys Gly Gln Thr Trp Gln Gly 
1               5                   10                  15      


Asp Gly Leu Leu Leu Arg Ser His Ala Ala Ser Arg Arg Phe Tyr Phe 
            20                  25                  30          


Val Ala Pro Asp Thr Asp Cys Gly Leu Trp Val Gln Ala Ala Ala Pro 
        35                  40                  45              


Gly Asp Arg Ile Arg Phe Gln Phe Arg Phe Phe Leu Val Tyr Ser Leu 
    50                  55                  60                  


Thr Pro Ala Pro Pro Ala Leu Asn Thr Ser Ser Pro Ala Pro Ala Asp 
65                  70                  75                  80  


Pro Cys Ala Pro Gly Ser Tyr Leu Gln Phe Tyr Glu Gly Pro Pro Gly 
                85                  90                  95      


Ala Pro Arg Pro Leu Gly Ser Pro Leu Cys Gly Leu Asn Ile Pro Val 
            100                 105                 110         


Pro Val Ala Ser Ser Gly Pro Phe Leu Gly Leu Arg Leu Val Thr Arg 
        115                 120                 125             


Gly Arg Gln Pro Arg Val Asp Phe Val Gly Glu Val Thr Ser Phe Arg 
    130                 135                 140                 


Leu Gly Pro Cys Gly Ala Tyr Phe Arg Cys Gln Asn Gly Arg Cys Ile 
145                 150                 155                 160 


Pro Ser Ser Leu Val Cys Asp Pro Trp Gly Met Asp Asn Cys Gly Asp 
                165                 170                 175     


Gly Ser Asp Gln Gly Ser Trp Ser Pro Ala Asp Cys Arg Gly Pro Ser 
            180                 185                 190         


Pro Val Pro Ser Gln Thr Gly Ser Thr Asp Ala His Thr Ser Arg Ser 
        195                 200                 205             


<210>  1574
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  1574

Gln Leu Leu Pro Gly Asn Asn Phe Thr Asn Glu Cys Asn Ile Pro Gly 
1               5                   10                  15      


Asn Phe Met Cys Ser Asn Gly Arg Cys Ile Pro Gly Ala Trp Gln Cys 
            20                  25                  30          


Asp Gly Leu Pro Asp Cys Phe Asp Lys Ser Asp Glu Lys Glu Cys Pro 
        35                  40                  45              


Lys Ala Lys Ser Lys Cys Gly Pro Thr Phe Phe Pro Cys Ala Ser Gly 
    50                  55                  60                  


Ile His Cys Ile Ile Gly Arg Phe Arg Cys Asn Gly Phe Glu Asp Cys 
65                  70                  75                  80  


Pro Asp Gly Ser Asp Glu Glu Asn Cys Thr Ala Asn Pro Leu Leu Cys 
                85                  90                  95      


Ser Thr Ala Arg Tyr His Cys Lys Asn Gly Leu Cys Ile Asp Lys Ser 
            100                 105                 110         


Phe Ile Cys Asp Gly Gln Asn Asn Cys Gln Asp Asn Ser Asp Glu Glu 
        115                 120                 125             


Ser Cys Glu Ser Ser Gln Glu Pro Gly Ser Gly Gln Val Phe Val Thr 
    130                 135                 140                 


Ser Glu Asn Gln Leu Val Tyr Tyr Pro Ser Ile Thr 
145                 150                 155     


<210>  1575
<211>  310
<212>  PRT
<213>  Homo Sapiens

<400>  1575

Gly Thr Ser Asn Leu Ser Glu Thr Glu Pro Pro Leu Trp Lys Glu Ser 
1               5                   10                  15      


Pro Gly Gln Leu Ser Asp Tyr Arg Val Glu Asn Ser Met Tyr Ile Ile 
            20                  25                  30          


Asn Pro Trp Val Tyr Leu Glu Arg Met Gly Met Tyr Lys Ile Ile Leu 
        35                  40                  45              


Asn Gln Thr Ala Arg Tyr Phe Ala Lys Phe Ala Pro Asp Asn Glu Gln 
    50                  55                  60                  


Asn Ile Leu Trp Gly Leu Pro Leu Gln Tyr Gly Trp Gln Tyr Arg Thr 
65                  70                  75                  80  


Gly Arg Leu Ala Asp Pro Thr Arg Arg Thr Asn Cys Gly Tyr Glu Ser 
                85                  90                  95      


Gly Asp His Met Cys Ile Ser Val Asp Ser Trp Trp Ala Asp Leu Asn 
            100                 105                 110         


Tyr Phe Leu Ser Ser Leu Pro Phe Leu Ala Ala Val Asp Ser Gly Val 
        115                 120                 125             


Met Gly Ile Ser Ser Asp Gln Val Arg Leu Leu Pro Pro Pro Lys Asn 
    130                 135                 140                 


Glu Arg Lys Phe Cys Tyr Asp Val Ser Ser Cys Arg Ser Ser Phe Pro 
145                 150                 155                 160 


Glu Thr Met Asn Lys Trp Asn Thr Phe Tyr Gln Tyr Leu Gln Ser Pro 
                165                 170                 175     


Phe Ser Lys Phe Asp Asp Leu Leu Lys Tyr Leu Trp Ala Ala His Thr 
            180                 185                 190         


Ser Thr Leu Ala Asp Asn Ile Lys Ser Phe Glu Asp Arg Tyr Asp Tyr 
        195                 200                 205             


Tyr Ser Lys Ala Glu Ala His Phe Glu Arg Ser Trp Val Leu Ala Val 
    210                 215                 220                 


Asp His Leu Ala Ala Val Leu Phe Pro Thr Thr Leu Ile Arg Ser Tyr 
225                 230                 235                 240 


Lys Phe Gln Lys Gly Met Pro Pro Arg Ile Leu Leu Asn Thr Asp Val 
                245                 250                 255     


Ala Pro Phe Ile Ser Asp Phe Thr Ala Phe Gln Asn Val Val Leu Val 
            260                 265                 270         


Leu Leu Asn Met Leu Asp Asn Val Asp Lys Ser Ile Gly Tyr Leu Cys 
        275                 280                 285             


Thr Glu Lys Ser Asn Val Tyr Arg Asp His Ser Glu Ser Ser Ser Arg 
    290                 295                 300                 


Ser Tyr Gly Asn Asn Ser 
305                 310 


<210>  1576
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1576

Ser Arg Glu Pro Leu Arg Pro Trp Cys His Pro Ile Asn Ala Ile Leu 
1               5                   10                  15      


Ala Val Glu Lys Glu Gly Cys Pro Val Cys Ile Thr Val Asn Thr Thr 
            20                  25                  30          


Ile Cys Ala Gly Tyr Cys Pro Thr Met Met Arg Val Leu Gln Ala Val 
        35                  40                  45              


Leu Pro Pro Leu Pro Gln Val Val Cys Thr Tyr Arg Asp Val Arg Phe 
    50                  55                  60                  


Glu Ser Ile Arg Leu Pro Gly Cys Pro Arg Gly Val Asp Pro Val Val 
65                  70                  75                  80  


Ser Phe Pro Val Ala Leu Ser Cys Arg Cys Gly Pro Cys Arg Arg Ser 
                85                  90                  95      


Thr Ser Asp Cys Gly Gly Pro Lys Asp His Pro Leu Thr Cys Asp His 
            100                 105                 110         


Pro Gln Leu Ser Gly Leu Leu Phe Leu 
        115                 120     


<210>  1577
<211>  83
<212>  PRT
<213>  Homo Sapiens

<400>  1577

Ala Thr Cys Lys Asp Glu Lys Gly Lys Gln Glu Met Glu Thr Gly Gln 
1               5                   10                  15      


Gln Pro Ser Gly Leu Ser Ala Thr Leu Thr Lys Val Lys Cys Ala Lys 
            20                  25                  30          


Arg Gln Lys Thr Val Val Arg Val Arg Phe Tyr Met Leu Ser Met Lys 
        35                  40                  45              


Asn Lys Ala Cys Arg Lys Asn Leu Ser Lys Gly Tyr Asn Gln Arg Pro 
    50                  55                  60                  


Glu Gly Ser Lys Glu Glu Ser His Met Val Val Lys Glu Lys Arg Lys 
65                  70                  75                  80  


Gly Asp His 
            


<210>  1578
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  1578

Gln His Phe Ser Ala Ala Asp Ser Pro Gly Thr Glu Phe Thr Pro Ala 
1               5                   10                  15      


Thr Thr Thr Ser Arg Leu Leu His Val Leu Tyr Val Cys Ser Cys Ser 
            20                  25                  30          


Leu Val Ala Glu Lys Asp Asp Phe Ser Ser Pro His Ser His Ser Leu 
        35                  40                  45              


Leu Leu Val Ser Leu Pro Glu Pro His Phe Glu Leu Ser Glu Gly Leu 
    50                  55                  60                  


Arg Leu Ala Phe Arg Gly Ser Gln Ser Ser Asp Ser Ile Arg Tyr Arg 
65                  70                  75                  80  


Arg Gly Gly Asn Glu Gly Val Arg Pro Trp Arg Ala Gly Ala Thr Gly 
                85                  90                  95      


Leu Pro Pro Thr Gly Lys Asp Ile Ser Val Ser Leu Ala His Glu Leu 
            100                 105                 110         


Tyr Ser Leu Leu Lys Gln Leu Gln Met Ser Ile 
        115                 120             


<210>  1579
<211>  390
<212>  PRT
<213>  Homo Sapiens

<400>  1579

Val His Met Pro Thr Lys Ala Val Asp Pro Glu Ala Phe Met Asn Ile 
1               5                   10                  15      


Ser Glu Ile Ile Gln His Gln Gly Tyr Pro Cys Glu Glu Tyr Glu Val 
            20                  25                  30          


Ala Thr Glu Asp Gly Tyr Ile Leu Ser Val Asn Arg Ile Pro Arg Gly 
        35                  40                  45              


Leu Val Gln Pro Lys Lys Thr Gly Ser Arg Pro Val Val Leu Leu Gln 
    50                  55                  60                  


His Gly Leu Val Gly Gly Ala Ser Asn Trp Ile Ser Asn Leu Pro Asn 
65                  70                  75                  80  


Asn Ser Leu Gly Phe Ile Leu Ala Asp Ala Gly Phe Asp Val Trp Met 
                85                  90                  95      


Gly Asn Ser Arg Gly Asn Ala Trp Ser Arg Lys His Lys Thr Leu Ser 
            100                 105                 110         


Ile Asp Gln Asp Glu Phe Trp Ala Phe Ser Tyr Asp Glu Met Ala Arg 
        115                 120                 125             


Phe Asp Leu Pro Ala Val Ile Asn Phe Ile Leu Gln Lys Thr Gly Gln 
    130                 135                 140                 


Glu Lys Ile Tyr Tyr Val Gly Tyr Ser Gln Gly Thr Thr Met Gly Phe 
145                 150                 155                 160 


Ile Ala Phe Ser Thr Met Pro Glu Leu Ala Gln Lys Ile Lys Met Tyr 
                165                 170                 175     


Phe Ala Leu Ala Pro Ile Ala Thr Val Lys His Ala Lys Ser Pro Gly 
            180                 185                 190         


Thr Lys Phe Leu Leu Leu Pro Asp Met Met Ile Lys Gly Leu Phe Gly 
        195                 200                 205             


Lys Lys Glu Phe Leu Tyr Gln Thr Arg Phe Leu Arg Gln Leu Val Ile 
    210                 215                 220                 


Tyr Leu Cys Gly Gln Val Ile Leu Asp Gln Ile Cys Ser Asn Ile Met 
225                 230                 235                 240 


Leu Leu Leu Gly Gly Phe Asn Thr Asn Asn Met Asn Met Ser Arg Ala 
                245                 250                 255     


Ser Val Tyr Ala Ala His Thr Leu Ala Gly Thr Ser Val Gln Asn Ile 
            260                 265                 270         


Leu His Trp Ser Gln Ala Val Asn Ser Gly Glu Leu Arg Ala Phe Asp 
        275                 280                 285             


Trp Gly Ser Glu Thr Lys Asn Leu Glu Lys Cys Asn Gln Pro Thr Pro 
    290                 295                 300                 


Val Arg Tyr Arg Val Arg Asp Met Thr Val Pro Thr Ala Met Trp Thr 
305                 310                 315                 320 


Gly Gly Gln Asp Trp Leu Ser Asn Pro Glu Asp Val Lys Met Leu Leu 
                325                 330                 335     


Ser Glu Val Thr Asn Leu Ile Tyr His Lys Asn Ile Pro Glu Trp Ala 
            340                 345                 350         


His Val Asp Phe Ile Trp Gly Leu Asp Ala Pro His Arg Met Tyr Asn 
        355                 360                 365             


Glu Ile Ile His Leu Met Gln Gln Glu Glu Thr Asn Leu Ser Gln Gly 
    370                 375                 380                 


Arg Cys Glu Ala Val Leu 
385                 390 


<210>  1580
<211>  380
<212>  PRT
<213>  Homo Sapiens

<400>  1580

Gly Gly Phe Leu Asp Leu Glu Asn Glu Val Asn Pro Glu Val Trp Met 
1               5                   10                  15      


Asn Thr Ser Glu Ile Ile Ile Tyr Asn Gly Tyr Pro Ser Glu Glu Tyr 
            20                  25                  30          


Glu Val Thr Thr Glu Asp Gly Tyr Ile Leu Leu Val Asn Arg Ile Pro 
        35                  40                  45              


Tyr Gly Arg Thr His Ala Arg Ser Thr Gly Pro Arg Pro Val Val Tyr 
    50                  55                  60                  


Met Gln His Ala Leu Phe Ala Asp Asn Ala Tyr Trp Leu Glu Asn Tyr 
65                  70                  75                  80  


Ala Asn Gly Ser Leu Gly Phe Leu Leu Ala Asp Ala Gly Tyr Asp Val 
                85                  90                  95      


Trp Met Gly Asn Ser Arg Gly Asn Thr Trp Ser Arg Arg His Lys Thr 
            100                 105                 110         


Leu Ser Glu Thr Asp Glu Lys Phe Trp Ala Phe Ser Phe Asp Glu Met 
        115                 120                 125             


Ala Lys Tyr Asp Leu Pro Gly Val Ile Asp Phe Ile Val Asn Lys Thr 
    130                 135                 140                 


Gly Gln Glu Lys Leu Tyr Phe Ile Gly His Ser Leu Gly Thr Thr Ile 
145                 150                 155                 160 


Gly Phe Val Ala Phe Ser Thr Met Pro Glu Leu Ala Gln Arg Ile Lys 
                165                 170                 175     


Met Asn Phe Ala Leu Gly Pro Thr Ile Ser Phe Lys Tyr Pro Thr Gly 
            180                 185                 190         


Ile Phe Thr Arg Phe Phe Leu Leu Pro Asn Ser Ile Ile Lys Ala Val 
        195                 200                 205             


Phe Gly Thr Lys Gly Phe Phe Leu Glu Asp Lys Lys Thr Lys Ile Ala 
    210                 215                 220                 


Ser Thr Lys Ile Cys Asn Asn Lys Ile Leu Trp Leu Ile Cys Ser Glu 
225                 230                 235                 240 


Phe Met Ser Leu Trp Ala Gly Ser Asn Lys Lys Asn Met Asn Gln Ser 
                245                 250                 255     


Arg Met Asp Val Tyr Met Ser His Ala Pro Thr Gly Ser Ser Val His 
            260                 265                 270         


Asn Ile Leu His Ile Lys Gln Leu Tyr His Ser Asp Glu Phe Arg Ala 
        275                 280                 285             


Tyr Asp Trp Gly Asn Asp Ala Asp Asn Met Lys His Tyr Asn Gln Ser 
    290                 295                 300                 


His Pro Pro Ile Tyr Asp Leu Thr Ala Met Lys Val Pro Thr Ala Ile 
305                 310                 315                 320 


Trp Ala Gly Gly His Asp Val Leu Val Thr Pro Gln Asp Val Ala Arg 
                325                 330                 335     


Ile Leu Pro Gln Ile Lys Ser Leu His Tyr Phe Lys Leu Leu Pro Asp 
            340                 345                 350         


Trp Asn His Phe Asp Phe Val Trp Gly Leu Asp Ala Pro Gln Arg Met 
        355                 360                 365             


Tyr Ser Glu Ile Ile Ala Leu Met Lys Ala Tyr Ser 
    370                 375                 380 


<210>  1581
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  1581

Ser Pro Gly Pro Lys Asp Gly Ser Gln Thr Glu Lys Thr Pro Ser Ala 
1               5                   10                  15      


Asp Gln Asn Gln Glu Gln Phe Glu Glu His Phe Val Ala Ser Ser Val 
            20                  25                  30          


Gly Glu Met Trp Gln Val Val Asp Met Ala Gln Gln Glu Glu Asp Gln 
        35                  40                  45              


Ser Ser Lys Thr Ala Ala Val His Lys His Ser Phe His Leu Ser Phe 
    50                  55                  60                  


Cys Phe Ser Leu Ala Ser Val Met Val Phe Ser Gly Gly Pro Leu Arg 
65                  70                  75                  80  


Arg Thr Phe Pro Asn Ile Gln Leu Cys Phe Met Leu Thr His 
                85                  90                  


<210>  1582
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  1582

Gly Pro Ser Val Gln Glu Cys Tyr His Ser Asn Gly Gln Ser Tyr Arg 
1               5                   10                  15      


Gly Thr Tyr Phe Thr Thr Val Thr Gly Arg Thr Cys Gln Ala Trp Ser 
            20                  25                  30          


Ser Met Thr Pro His Gln His Ser Arg Thr Pro Glu Lys Tyr Pro Asn 
        35                  40                  45              


Asp Gly Leu Ile Ser Asn Tyr Cys Arg Asn Pro Asp Cys Ser Ala Gly 
    50                  55                  60                  


Pro Trp Cys Tyr Thr Thr Asp Pro Asn Val Arg Trp Glu Tyr Cys Asn 
65                  70                  75                  80  


Leu Thr Arg Cys Ser Asp Asp Glu Gly Thr Val Phe Val Pro Leu Thr 
                85                  90                  95      


Val Ile Pro Val Pro Ser Leu Glu Asp Ser Phe Ile Gln Val Ala 
            100                 105                 110     


<210>  1583
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  1583

Gly Tyr Gly Pro Gln Lys Lys Leu Asn Leu Ser His Lys Gly Ile Gly 
1               5                   10                  15      


Glu Pro Cys Arg Arg His Glu Glu Cys Gln Ser Asn Cys Cys Thr Ile 
            20                  25                  30          


Asn Ser Leu Ala Pro His Thr Leu Cys Thr Pro Lys Thr Ile Phe Leu 
        35                  40                  45              


Gln Cys Leu Pro Trp Arg Lys Pro Asn Gly Tyr Arg Cys Ser His Asp 
    50                  55                  60                  


Ser Glu Cys Gln Ser Ser Cys Cys Val Arg Asn Asn Ser Pro Gln Glu 
65                  70                  75                  80  


Leu Cys Thr Pro Gln Ser Val Phe Leu Gln Cys Val Pro Trp Arg Lys 
                85                  90                  95      


Pro Asn Gly Asp Phe Cys Ser Ser His Gln Glu Cys His Ser Gln Cys 
            100                 105                 110         


Cys Ile Gln Leu Arg Glu Tyr Ser Pro Phe Arg Cys Ile Pro Arg Thr 
        115                 120                 125             


Gly Ile Leu Ala Gln Cys Leu Pro Leu 
    130                 135         


<210>  1584
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  1584

Met Arg His Glu Glu Leu Leu Thr Lys Thr Phe Gln Gly Pro Ala Val 
1               5                   10                  15      


Val Cys Gly Thr Pro Thr Ser His Val Tyr Met Phe Lys Asn Gly Ser 
            20                  25                  30          


Gly Asp Ser Gly Asp Ser Ser Glu Glu Glu Ser His Arg Val Val Leu 
        35                  40                  45              


Arg Pro Arg Gly Lys Glu Arg His Lys Ser Gly Val His Gln Pro Pro 
    50                  55                  60                  


Gln Ala Gly Ala Gly Asp Val Val Leu Leu Gln Arg Glu Leu Ala Gln 
65                  70                  75                  80  


Glu Asp Ser Leu Asn Lys Leu Ala Leu Gln Tyr Gly Cys Lys Val Ala 
                85                  90                  95      


Asp Ile Lys Lys Val Asn Asn Phe Ile Arg Glu Gln Asp Leu Tyr Ala 
            100                 105                 110         


Leu Lys Ser Val Lys Ile Pro Val Arg Asn His Gly Ile Leu Met Glu 
        115                 120                 125             


Thr His Lys Glu Leu Lys Pro Leu Leu Ser Pro Ser Ser Glu Thr Thr 
    130                 135                 140                 


Val Thr Val Glu Leu Pro Glu Ala Asp Arg Ala Gly Ala Gly Thr Gly 
145                 150                 155                 160 


Ala Gln Ala Gly Gln Leu Met Gly Phe Phe Lys Gly Ile Asp Gln Asp 
                165                 170                 175     


Ile Glu Arg Ala Val Gln Ser Glu Ile Phe Leu His Glu Ser Tyr Cys 
            180                 185                 190         


Met Asp Thr Ser His Gln Pro Leu Leu Pro Ala Pro Pro Lys Thr Pro 
        195                 200                 205             


Met Asp Gly Ala Asp Cys Gly Ile Gln 
    210                 215         


<210>  1585
<211>  260
<212>  PRT
<213>  Homo Sapiens

<400>  1585

Ser Pro Thr Ile Phe Tyr Arg Asp Cys Trp Ile Arg Arg Phe Pro Gly 
1               5                   10                  15      


Leu Leu Ile Asn Leu Glu Glu Ser Gln Lys Leu Gly Ala Gln Phe Leu 
            20                  25                  30          


Lys Tyr Tyr Ser Glu Ser Thr Gly Gln Lys Cys Ser Arg Ser Cys Cys 
        35                  40                  45              


Leu Arg Lys Asp Val Ser Cys Asn Leu Ala Val Phe Tyr His Ser Pro 
    50                  55                  60                  


Ile His Asp Asn Ile Asn Cys Leu His Val His Cys Pro Thr Leu Glu 
65                  70                  75                  80  


Ser Cys Ile Leu Glu Pro Gly Thr Ser Ala Ile Leu Tyr Asn Ile Thr 
                85                  90                  95      


Asp Gly Ile Asp Pro Asp Leu Leu Val Phe Glu Gln Ser Pro Thr Tyr 
            100                 105                 110         


Leu Asn Thr Arg Ser Ser Ser Asn Arg Trp Asp Arg Leu Arg Ile Leu 
        115                 120                 125             


Lys Ala Met Asn Leu Asp Lys Gln Thr Thr Thr Ile Asn Gly Met Leu 
    130                 135                 140                 


Pro Ser Thr Glu Ala Pro Ser Ser Thr Thr His Gln Asp Leu Val Val 
145                 150                 155                 160 


Asn Thr Asn Ser Thr Ser Tyr Ser Lys Glu Leu Thr Thr Asp Phe Trp 
                165                 170                 175     


Ala Arg Phe Thr Ser Leu Asn Glu Ser Ile Thr Thr Lys Ile Asn Lys 
            180                 185                 190         


Val Ser Pro Ser Thr Asp Phe Ile Ser Asn Pro Asp Asn Lys Thr Ile 
        195                 200                 205             


Ser Pro Phe Phe Glu Pro Ile Asp Thr Lys Leu Ser His Met Pro Val 
    210                 215                 220                 


Pro Pro Gly Leu Asn Ser Ser Lys Gln Leu Leu Asn Lys Thr Lys Gly 
225                 230                 235                 240 


Tyr Asn Ser Arg Asn His Thr Ser Ala Asn Glu Asp Glu Val Ser Val 
                245                 250                 255     


Thr Ser Lys Thr 
            260 


<210>  1586
<211>  318
<212>  PRT
<213>  Homo Sapiens

<400>  1586

Gln Gly Leu Thr Gln Thr Pro Thr Glu Met Gln Arg Val Ser Leu Arg 
1               5                   10                  15      


Phe Gly Gly Pro Met Thr Arg Ser Tyr Arg Ser Thr Ala Arg Thr Gly 
            20                  25                  30          


Leu Pro Arg Lys Thr Arg Ile Ile Leu Glu Asp Glu Asn Asp Ala Met 
        35                  40                  45              


Ala Asp Ala Asp Arg Leu Ala Gly Pro Ala Ala Ala Glu Leu Leu Ala 
    50                  55                  60                  


Ala Thr Val Ser Thr Gly Phe Ser Arg Ser Ser Ala Ile Asn Glu Glu 
65                  70                  75                  80  


Asp Gly Ser Ser Glu Glu Gly Val Val Ile Asn Ala Gly Lys Asp Ser 
                85                  90                  95      


Thr Ser Arg Glu Leu Pro Ser Ala Thr Pro Asn Thr Ala Gly Ser Ser 
            100                 105                 110         


Ser Thr Arg Phe Ile Ala Asn Ser Gln Glu Pro Glu Ile Arg Leu Thr 
        115                 120                 125             


Ser Ser Leu Pro Arg Ser Pro Gly Arg Ser Thr Glu Asp Leu Pro Gly 
    130                 135                 140                 


Ser Gln Ala Thr Leu Ser Gln Trp Ser Thr Pro Gly Ser Thr Pro Ser 
145                 150                 155                 160 


Arg Trp Pro Ser Pro Ser Pro Thr Ala Met Pro Ser Pro Glu Asp Leu 
                165                 170                 175     


Arg Leu Val Leu Met Pro Trp Gly Pro Trp His Cys His Cys Lys Ser 
            180                 185                 190         


Gly Thr Met Ser Arg Ser Arg Ser Gly Lys Leu His Gly Leu Ser Gly 
        195                 200                 205             


Arg Leu Arg Val Gly Ala Leu Ser Gln Leu Arg Thr Glu His Lys Pro 
    210                 215                 220                 


Cys Thr Tyr Gln Gln Cys Pro Cys Asn Arg Leu Arg Glu Glu Cys Pro 
225                 230                 235                 240 


Leu Asp Thr Ser Leu Cys Thr Asp Thr Asn Cys Ala Ser Gln Ser Thr 
                245                 250                 255     


Thr Ser Thr Arg Thr Thr Thr Thr Pro Phe Pro Thr Ile His Leu Arg 
            260                 265                 270         


Ser Ser Pro Ser Leu Pro Pro Ala Ser Pro Cys Pro Ala Leu Ala Phe 
        275                 280                 285             


Trp Lys Arg Val Arg Ile Gly Leu Glu Asp Ile Trp Asn Ser Leu Ser 
    290                 295                 300                 


Ser Val Phe Thr Glu Met Gln Pro Ile Asp Arg Asn Gln Arg 
305                 310                 315             


<210>  1587
<211>  270
<212>  PRT
<213>  Homo Sapiens

<400>  1587

Gly Tyr Ser Glu Glu Arg Cys Ser Trp Arg Gly Ser Gly Leu Thr Gln 
1               5                   10                  15      


Glu Pro Gly Ser Val Gly Gln Leu Ala Leu Ala Cys Ala Glu Gly Ala 
            20                  25                  30          


Val Glu Trp Leu Tyr Pro Ala Gly Ala Leu Arg Leu Thr Leu Gly Gly 
        35                  40                  45              


Pro Asp Pro Arg Ala Arg Pro Gly Ile Ala Cys Leu Arg Pro Val Arg 
    50                  55                  60                  


Pro Phe Ala Gly Ala Gln Val Phe Ala Glu Arg Ala Gly Gly Ala Leu 
65                  70                  75                  80  


Glu Leu Leu Leu Ala Glu Gly Pro Gly Pro Ala Gly Gly Arg Cys Val 
                85                  90                  95      


Arg Trp Gly Pro Arg Glu Arg Arg Ala Leu Phe Leu Gln Ala Thr Pro 
            100                 105                 110         


His Gln Asp Ile Ser Arg Arg Val Ala Ala Phe Arg Phe Glu Leu Arg 
        115                 120                 125             


Glu Asp Gly Arg Pro Glu Leu Pro Pro Gln Ala His Gly Leu Gly Val 
    130                 135                 140                 


Asp Gly Ala Cys Arg Pro Cys Ser Asp Ala Glu Leu Leu Leu Ala Ala 
145                 150                 155                 160 


Cys Thr Ser Asp Phe Val Ile His Gly Ile Ile His Gly Val Thr His 
                165                 170                 175     


Asp Val Glu Leu Gln Glu Ser Val Ile Thr Val Val Ala Ala Arg Val 
            180                 185                 190         


Leu Arg Gln Thr Pro Pro Leu Phe Gln Ala Gly Arg Ser Gly Asp Gln 
        195                 200                 205             


Gly Leu Thr Ser Ile Arg Thr Pro Leu Arg Cys Gly Val His Pro Gly 
    210                 215                 220                 


Pro Gly Thr Phe Leu Phe Met Gly Trp Ser Arg Phe Gly Glu Ala Arg 
225                 230                 235                 240 


Leu Gly Cys Ala Pro Arg Phe Gln Glu Phe Arg Arg Ala Tyr Glu Ala 
                245                 250                 255     


Ala Arg Ala Ala His Leu His Pro Cys Glu Val Ala Leu His 
            260                 265                 270 


<210>  1588
<211>  266
<212>  PRT
<213>  Homo Sapiens

<400>  1588

Gln Tyr Ser Ser Asp Arg Cys Ser Trp Lys Gly Ser Gly Leu Thr His 
1               5                   10                  15      


Glu Ala His Arg Lys Glu Val Glu Gln Val Tyr Leu Arg Cys Ala Ala 
            20                  25                  30          


Gly Ala Val Glu Trp Met Tyr Pro Thr Gly Ala Leu Ile Val Asn Leu 
        35                  40                  45              


Arg Pro Asn Thr Phe Ser Pro Ala Arg His Leu Thr Val Cys Ile Arg 
    50                  55                  60                  


Ser Phe Thr Asp Ser Ser Gly Ala Asn Ile Tyr Leu Glu Lys Thr Gly 
65                  70                  75                  80  


Glu Leu Arg Leu Leu Val Pro Asp Gly Asp Gly Arg Pro Gly Arg Val 
                85                  90                  95      


Gln Cys Phe Gly Leu Glu Gln Gly Gly Leu Phe Val Glu Ala Thr Pro 
            100                 105                 110         


Gln Gln Asp Ile Gly Arg Arg Thr Thr Gly Phe Gln Tyr Glu Leu Val 
        115                 120                 125             


Arg Arg His Arg Ala Ser Asp Leu His Glu Leu Ser Ala Pro Cys Arg 
    130                 135                 140                 


Pro Cys Ser Asp Thr Glu Val Leu Leu Ala Val Cys Thr Ser Asp Phe 
145                 150                 155                 160 


Ala Val Arg Gly Ser Ile Gln Gln Val Thr His Glu Pro Glu Arg Gln 
                165                 170                 175     


Asp Ser Ala Ile His Leu Arg Val Ser Arg Leu Tyr Arg Gln Lys Ser 
            180                 185                 190         


Arg Val Phe Glu Pro Val Pro Glu Gly Asp Gly His Trp Gln Gly Arg 
        195                 200                 205             


Val Arg Thr Leu Leu Glu Cys Gly Val Arg Pro Gly His Gly Asp Phe 
    210                 215                 220                 


Leu Phe Thr Gly His Met His Phe Gly Glu Ala Arg Leu Gly Cys Ala 
225                 230                 235                 240 


Pro Arg Phe Lys Asp Phe Gln Arg Met Tyr Arg Asp Ala Gln Glu Arg 
                245                 250                 255     


Gly Leu Asn Pro Cys Glu Val Gly Thr Asp 
            260                 265     


<210>  1589
<211>  337
<212>  PRT
<213>  Homo Sapiens

<400>  1589

Cys Ala Glu Leu Arg Arg Ala Gly Pro Gly Ser Pro Thr Arg Ser Ala 
1               5                   10                  15      


Pro Pro Gly Pro Ala Trp Arg Pro Pro Gly Pro His Leu Pro Pro Ala 
            20                  25                  30          


Pro Gly Gln Pro Arg Gly Ala Ser Arg Arg Gln Val Thr Tyr Val Arg 
        35                  40                  45              


Ser Gly Arg Arg Ala Pro Pro Gly Gly Gly Gly Ser Gly Thr Pro Glu 
    50                  55                  60                  


Pro Gly Cys Cys Ala Pro Arg Gly Arg Pro Arg Arg Lys Gly Pro Arg 
65                  70                  75                  80  


Trp His Ile Asp Leu Gln Pro Trp Ala Gly Ser Ala Gln Ser Leu Asp 
                85                  90                  95      


Glu Glu Ala Trp Arg Phe Leu Arg Tyr Ile Ser Thr Thr Gln Ile Ala 
            100                 105                 110         


Cys Asn His Met Asn Thr Asp Ser Leu Ala Thr Asp Ser Ser Pro Thr 
        115                 120                 125             


His Lys Pro Trp Ser Val Cys Leu Asp Asp Arg Phe Asn Leu Ala His 
    130                 135                 140                 


Gln Ile Arg Asn Lys Gln Cys Arg Leu Tyr Ser Leu Gly Leu Gly Ser 
145                 150                 155                 160 


Asp Asp Thr His Phe Glu Val Ser Met Ala Asn Asn Gly Cys Glu Val 
                165                 170                 175     


His Arg Phe Asp Pro Ser Val Lys Ser Ala His Ile Leu Glu Ser Gln 
            180                 185                 190         


His Leu Trp Tyr His Arg Leu Ser Ile Asp Trp Arg Asp Pro His Pro 
        195                 200                 205             


Ala Val Ala Ala Gln Lys Pro His Ser Asn Thr Arg Lys Leu Gly Ser 
    210                 215                 220                 


Ile Leu Asn Glu Phe Gly His His Lys Ile Asp Val Leu Lys Ala Asp 
225                 230                 235                 240 


Leu Glu Ser Ala Glu Trp Lys Val Leu Glu Asn Leu Ile Leu Glu Asp 
                245                 250                 255     


Val Leu Glu Gln Ile Gly Gln Leu Ile Phe Glu Ile His Leu His Trp 
            260                 265                 270         


Pro Gly Phe Glu Val Ser Gly Ser Asp Ser Ser Val Val Arg Phe Trp 
        275                 280                 285             


Tyr Ser Leu Leu Lys Glu Leu Glu Gln Lys Asp Phe Arg Leu Phe His 
    290                 295                 300                 


Ser Tyr Lys Asp Leu Ser Lys Pro Gln Leu Phe Leu Lys Lys Asp Ile 
305                 310                 315                 320 


Phe Asn Ala Ser Ser Cys Tyr Thr Leu Ser Trp Val Asn Thr Arg Trp 
                325                 330                 335     


Lys 
    


<210>  1590
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  1590

Leu Leu Gly Cys Trp Gln Pro Leu Cys Lys Ser Tyr Phe Pro Tyr Leu 
1               5                   10                  15      


Met Ala Val Leu Thr Pro Lys Ser Asn Arg Lys Met Glu Ser Lys Lys 
            20                  25                  30          


Arg Glu Leu Phe Ser Gln Ile Lys Gly Leu Thr Gly Ala Ser Gly Lys 
        35                  40                  45              


Val Ala Leu Leu Glu Leu Gly Cys Gly Thr Gly Ala Asn Phe Gln Phe 
    50                  55                  60                  


Tyr Pro Pro Gly Cys Arg Val Thr Cys Leu Asp Pro Asn Pro His Phe 
65                  70                  75                  80  


Glu Lys Phe Leu Thr Lys Ser Met Ala Glu Asn Arg His Leu Gln Tyr 
                85                  90                  95      


Glu Arg Phe Val Val Ala Pro Gly Glu Asp Met Arg Gln Leu Ala Asp 
            100                 105                 110         


Gly Ser Met Asp Val Val Val Cys Thr Leu Val Leu Cys Ser Val Gln 
        115                 120                 125             


Ser Pro Arg Lys Val Leu Gln Glu Val Arg Arg Val Leu Arg Pro Gly 
    130                 135                 140                 


Gly Val Leu Phe Phe Trp Glu His Val Ala Glu Pro Tyr Gly Ser Trp 
145                 150                 155                 160 


Ala Phe Met Trp Gln Gln Val Phe Glu Pro Thr Trp Lys His Ile Gly 
                165                 170                 175     


Asp Gly Cys Cys Leu Thr Arg Glu Thr Trp Lys Asp Leu Glu Asn Ala 
            180                 185                 190         


Gln Phe Ser Glu Ile Gln Met Glu Arg Gln Pro Pro Pro Leu Lys Trp 
        195                 200                 205             


Leu Pro Val Gly Pro His Ile Met Gly Lys Ala Val Lys 
    210                 215                 220     


<210>  1591
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  1591

Gln Leu Gln Ala Ala Pro Pro Ser Gly Ala Ser His Ser Pro Leu Pro 
1               5                   10                  15      


Ala Gly Gly Leu Thr Thr Thr Thr Thr Thr Pro Thr Ile Thr Thr Ser 
            20                  25                  30          


Gln Ala Ala Gly Thr Pro Lys Gly Gln Gln Glu Ser Gly Val Ser Pro 
        35                  40                  45              


Ser Pro Gln Ser Thr Cys Gly Gly Leu Leu Ser Gly Pro Arg Gly Phe 
    50                  55                  60                  


Phe Ser Ser Pro Asn Tyr Pro Asp Pro Tyr Pro Pro Asn Thr His Cys 
65                  70                  75                  80  


Val Trp His Ile Gln Val Ala Thr Asp His Ala Ile Gln Leu Lys Ile 
                85                  90                  95      


Glu Ala Leu Ser Ile Glu Ser Val Ala Ser Cys Leu Phe Asp Arg Leu 
            100                 105                 110         


Glu Leu Ser Pro Glu Pro Glu Gly Pro Leu Leu Arg Val Cys Gly Arg 
        115                 120                 125             


Val Pro Pro Pro Thr Leu Asn Thr Asn Ala Ser His Leu Leu Val Val 
    130                 135                 140                 


Phe Val Ser Asp Ser Ser Val Glu Gly Phe Gly Phe His Ala Trp Tyr 
145                 150                 155                 160 


Gln Ala Met Ala Pro Gly Arg Gly Ser Cys Ala His Asp Glu Phe Arg 
                165                 170                 175     


Cys Asp Gln Leu Ile Cys Leu Leu Pro Asp Ser Val Cys Asp Gly Phe 
            180                 185                 190         


Ala Asn Cys Ala Asp Gly Ser Asp Glu Thr Asn Cys Ser Ala Lys Phe 
        195                 200                 205             


Ser Gly Cys Gly Gly Asn Leu Thr Gly Leu Gln Gly Thr Phe Ser Thr 
    210                 215                 220                 


Pro Ser Tyr Leu Gln Gln Tyr Pro His Gln Leu Leu Cys Thr Trp His 
225                 230                 235                 240 


Ile Ser Val Pro Ala Gly His Ser Ile Glu Leu Gln Phe His Asn Phe 
                245                 250                 255     


Ser Leu Glu Ala Gln Asp Glu Cys Lys Phe Asp Tyr Val Glu Val Tyr 
            260                 265                 270         


Glu Thr Ser Ser Ser Gly Ala Phe Ser Leu Leu Gly Arg Phe Cys Gly 
        275                 280                 285             


Ala Glu Pro Pro Pro His Leu Val Ser Ser His His Glu Leu Ala Val 
    290                 295                 300                 


Leu Phe Arg Thr Asp His Gly Ile Ser Ser Gly Gly Phe Ser Ala Thr 
305                 310                 315                 320 


Tyr Leu Ala Phe Asn Ala Thr Glu Asn Pro Cys Gly Pro Ser Glu Leu 
                325                 330                 335     


Ser Cys Gln Ala Gly Gly Cys Lys Gly Val Gln Trp Met Cys Asp Met 
            340                 345                 350         


Trp Arg Asp Cys Thr Asp Gly Ser Asp Asp Asn Cys Ser Gly Pro Leu 
        355                 360                 365             


Phe Pro Pro Pro Glu Leu Ala Cys Glu Pro Val Gln Val Glu Met Cys 
    370                 375                 380                 


Leu Gly Leu Ser Tyr Asn Thr Thr Ala Phe Pro Asn Ile Trp Val Gly 
385                 390                 395                 400 


Met Ile Thr Gln Glu Glu Val Val Glu Val Leu Ser Gly Tyr Lys Ser 
                405                 410                 415     


Leu Thr Ser Leu Pro Cys Tyr Gln His Phe Arg Arg Leu Leu Cys Gly 
            420                 425                 430         


Leu Leu Val Pro Arg Cys Thr Pro Leu Gly Ser Val Leu Pro Pro Cys 
        435                 440                 445             


Arg Ser Val Cys Gln Glu Ala Glu His Gln Cys Gln Ser Gly Leu Ala 
    450                 455                 460                 


Leu Leu Gly Thr Pro Trp Pro Phe Asn Cys Asn Arg Leu Pro Glu Ala 
465                 470                 475                 480 


Ala Asp Leu Glu Ala Cys Ala Gln Pro 
                485                 


<210>  1592
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1592

Tyr Glu Ser His Glu Ser Met Glu Ser Tyr Glu Leu Asn Pro Phe Ile 
1               5                   10                  15      


Asn Arg Arg Asn Ala Asn Thr Phe Ile Ser Pro Gln Gln Arg Trp Arg 
            20                  25                  30          


Ala Lys Val Gln Glu Arg Ile Arg Glu Arg Ser Lys Pro Val His Glu 
        35                  40                  45              


Leu Asn Arg Glu Ala Cys Asp Asp Tyr Arg Leu Cys Glu Arg Tyr Ala 
    50                  55                  60                  


Met Val Tyr Gly Tyr Asn Ala Ala Tyr Asn Arg Tyr Phe 
65                  70                  75          


<210>  1593
<211>  391
<212>  PRT
<213>  Homo Sapiens

<400>  1593

Phe Val Leu Ser Gly Gly Arg Trp Glu Lys Thr Asp Leu Thr Tyr Arg 
1               5                   10                  15      


Ile Leu Arg Phe Pro Trp Gln Leu Val Gln Glu Gln Val Arg Gln Thr 
            20                  25                  30          


Met Ala Glu Ala Leu Lys Val Trp Ser Asp Val Thr Pro Leu Thr Phe 
        35                  40                  45              


Thr Glu Val His Glu Gly Arg Ala Asp Ile Met Ile Asp Phe Ala Arg 
    50                  55                  60                  


Tyr Trp His Gly Asp Asp Leu Pro Phe Asp Gly Pro Gly Gly Ile Leu 
65                  70                  75                  80  


Ala His Ala Phe Phe Pro Lys Thr His Arg Glu Gly Asp Val His Phe 
                85                  90                  95      


Asp Tyr Asp Glu Thr Trp Thr Ile Gly Asp Asp Gln Gly Thr Asp Leu 
            100                 105                 110         


Leu Gln Val Ala Ala His Glu Phe Gly His Val Leu Gly Leu Gln His 
        115                 120                 125             


Thr Thr Ala Ala Lys Ala Leu Met Ser Ala Phe Tyr Thr Phe Arg Tyr 
    130                 135                 140                 


Pro Leu Ser Leu Ser Pro Asp Asp Cys Arg Gly Val Gln His Leu Tyr 
145                 150                 155                 160 


Gly Gln Pro Trp Pro Thr Val Thr Ser Arg Thr Pro Ala Leu Gly Pro 
                165                 170                 175     


Gln Ala Gly Ile Asp Thr Asn Glu Ile Ala Pro Leu Glu Pro Asp Ala 
            180                 185                 190         


Pro Pro Asp Ala Cys Glu Ala Ser Phe Asp Ala Val Ser Thr Ile Arg 
        195                 200                 205             


Gly Glu Leu Phe Phe Phe Lys Ala Gly Phe Val Trp Arg Leu Arg Gly 
    210                 215                 220                 


Gly Gln Leu Gln Pro Gly Tyr Pro Ala Leu Ala Ser Arg His Trp Gln 
225                 230                 235                 240 


Gly Leu Pro Ser Pro Val Asp Ala Ala Phe Glu Asp Ala Gln Gly His 
                245                 250                 255     


Ile Trp Phe Phe Gln Gly Ala Gln Tyr Trp Val Tyr Asp Gly Glu Lys 
            260                 265                 270         


Pro Val Leu Gly Pro Ala Pro Leu Thr Glu Leu Gly Leu Val Arg Phe 
        275                 280                 285             


Pro Val His Ala Ala Leu Val Trp Gly Pro Glu Lys Asn Lys Ile Tyr 
    290                 295                 300                 


Phe Phe Arg Gly Arg Asp Tyr Trp Arg Phe His Pro Ser Thr Arg Arg 
305                 310                 315                 320 


Val Asp Ser Pro Val Pro Arg Arg Ala Thr Asp Trp Arg Gly Val Pro 
                325                 330                 335     


Ser Glu Ile Asp Ala Ala Phe Gln Asp Ala Asp Gly Tyr Ala Tyr Phe 
            340                 345                 350         


Leu Arg Gly Arg Leu Tyr Trp Lys Phe Asp Pro Val Lys Val Lys Ala 
        355                 360                 365             


Leu Glu Gly Phe Pro Arg Leu Val Gly Pro Asp Phe Phe Gly Cys Ala 
    370                 375                 380                 


Glu Pro Ala Asn Thr Phe Leu 
385                 390     


<210>  1594
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  1594

Ser Pro Arg Ala Pro Leu Ser Leu Ser Arg Arg Gly Trp Gln Pro Arg 
1               5                   10                  15      


Gly Tyr Pro Asp Gly Gly Ala Ala Gln Ala Phe Ser Lys Arg Thr Leu 
            20                  25                  30          


Ser Trp Arg Leu Leu Gly Glu Ala Leu Ser Ser Gln Leu Ser Val Ala 
        35                  40                  45              


Asp Gln Arg Arg Ile Val Ala Leu Ala Phe Arg Met Trp Ser Glu Val 
    50                  55                  60                  


Thr Pro Leu Asp Phe Arg Glu Asp Leu Ala Ala Pro Gly Ala Ala Val 
65                  70                  75                  80  


Asp Ile Lys Leu Gly Phe Gly Arg Gly Arg His Leu Gly Cys Pro Arg 
                85                  90                  95      


Ala Phe Asp Gly Ser Gly Gln Glu Phe Ala His Ala Trp Arg Leu Gly 
            100                 105                 110         


Asp Ile His Phe Asp Asp Asp Glu His Phe Thr Pro Pro Thr Ser Asp 
        115                 120                 125             


Thr Gly Ile Ser Leu Leu Lys Val Ala Val His Glu Ile Gly His Val 
    130                 135                 140                 


Leu Gly Leu Pro His Thr Tyr Arg Thr Gly Ser Ile Met Gln Pro Asn 
145                 150                 155                 160 


Tyr Ile Pro Gln Glu Pro Ala Phe Glu Leu Asp Trp Ser Asp Arg Lys 
                165                 170                 175     


Ala Ile Gln Lys Leu Tyr Gly Ser Cys Glu Gly Ser Phe Asp Thr Ala 
            180                 185                 190         


Phe Asp Trp Ile Arg Lys Glu Arg Asn Gln Tyr Gly Glu Val Met Val 
        195                 200                 205             


Arg Phe Ser Thr Tyr Phe Phe Arg Asn Ser Trp Tyr Trp Leu Tyr Glu 
    210                 215                 220                 


Asn Arg Asn Asn Arg Thr Arg Tyr Gly Asp Pro Ile Gln Ile Leu Thr 
225                 230                 235                 240 


Gly Trp Pro Gly Ile Pro Thr His Asn Ile Asp Ala Phe Val His Ile 
                245                 250                 255     


Trp Thr Trp Lys Arg Asp Glu Arg Tyr Phe Phe Gln Gly Asn Gln Tyr 
            260                 265                 270         


Trp Arg Tyr Asp Ser Asp Lys Asp Gln Ala Leu Thr Glu Asp Glu Gln 
        275                 280                 285             


Gly Lys Ser Tyr Pro Lys Leu Ile Ser Glu Gly Phe Pro Gly Ile Pro 
    290                 295                 300                 


Ser Pro Leu Asp Thr Ala Phe Tyr Asp Arg Arg Gln Lys Leu Ile Tyr 
305                 310                 315                 320 


Phe Phe Lys Glu Ser Leu Val Phe Ala Phe Asp Val Asn Arg Asn Arg 
                325                 330                 335     


Val Leu Asn Ser Tyr Pro Lys Arg Ile Thr Glu Val Phe Pro Ala Val 
            340                 345                 350         


Ile Pro Gln Asn His Pro Phe Arg Asn Ile Asp Ser Ala Tyr Tyr Ser 
        355                 360                 365             


Tyr Ala Tyr Asn Ser Ile Phe Phe Phe Lys Gly Asn Ala Tyr Trp Lys 
    370                 375                 380                 


Val Val Asn Asp Lys Asp Lys Gln Gln Asn Ser Trp Leu Pro Ala Asn 
385                 390                 395                 400 


Gly Leu Phe Pro Lys Lys Phe Ile Ser Glu Lys Trp Phe Asp Val Cys 
                405                 410                 415     


Asp Val His Ile Ser Thr Leu Asn Met 
            420                 425 


<210>  1595
<211>  432
<212>  PRT
<213>  Homo Sapiens

<400>  1595

Tyr Ala Leu Ser Gly Ser Val Trp Lys Lys Arg Thr Leu Thr Trp Arg 
1               5                   10                  15      


Val Arg Ser Phe Pro Gln Ser Ser Gln Leu Ser Gln Glu Thr Val Arg 
            20                  25                  30          


Val Leu Met Ser Tyr Ala Leu Met Ala Trp Gly Met Glu Ser Gly Leu 
        35                  40                  45              


Thr Phe His Glu Val Asp Ser Pro Gln Gly Gln Glu Pro Asp Ile Leu 
    50                  55                  60                  


Ile Asp Phe Ala Arg Ala Phe His Gln Asp Ser Tyr Pro Phe Asp Gly 
65                  70                  75                  80  


Leu Gly Gly Thr Leu Ala His Ala Phe Phe Pro Gly Glu His Pro Ile 
                85                  90                  95      


Ser Gly Asp Thr His Phe Asp Asp Glu Glu Thr Trp Thr Phe Gly Ser 
            100                 105                 110         


Lys Asp Gly Glu Gly Thr Asp Leu Phe Ala Val Ala Val His Glu Phe 
        115                 120                 125             


Gly His Ala Leu Gly Leu Gly His Ser Ser Ala Pro Asn Ser Ile Met 
    130                 135                 140                 


Arg Pro Phe Tyr Gln Gly Pro Val Gly Asp Pro Asp Lys Tyr Arg Leu 
145                 150                 155                 160 


Ser Gln Asp Asp Arg Asp Gly Leu Gln Gln Leu Tyr Gly Lys Ala Pro 
                165                 170                 175     


Gln Thr Pro Tyr Asp Lys Pro Thr Arg Lys Pro Leu Ala Pro Pro Pro 
            180                 185                 190         


Gln Pro Pro Ala Ser Pro Thr His Ser Pro Ser Phe Pro Ile Pro Asp 
        195                 200                 205             


Arg Cys Glu Gly Asn Phe Asp Ala Ile Ala Asn Ile Arg Gly Glu Thr 
    210                 215                 220                 


Phe Phe Phe Lys Gly Pro Trp Phe Trp Arg Leu Gln Pro Ser Gly Gln 
225                 230                 235                 240 


Leu Val Ser Pro Arg Pro Ala Arg Leu His Arg Phe Trp Glu Gly Leu 
                245                 250                 255     


Pro Ala Gln Val Arg Val Val Gln Ala Ala Tyr Ala Arg His Arg Asp 
            260                 265                 270         


Gly Arg Ile Leu Leu Phe Ser Gly Pro Gln Phe Trp Val Phe Gln Asp 
        275                 280                 285             


Arg Gln Leu Glu Gly Gly Ala Arg Pro Leu Thr Glu Leu Gly Leu Pro 
    290                 295                 300                 


Pro Gly Glu Glu Val Asp Ala Val Phe Ser Trp Pro Gln Asn Gly Lys 
305                 310                 315                 320 


Thr Tyr Leu Val Arg Gly Arg Gln Tyr Trp Arg Tyr Asp Glu Ala Ala 
                325                 330                 335     


Ala Arg Pro Asp Pro Gly Tyr Pro Arg Asp Leu Ser Leu Trp Glu Gly 
            340                 345                 350         


Ala Pro Pro Ser Pro Asp Asp Val Thr Val Ser Asn Ala Gly Asp Thr 
        355                 360                 365             


Tyr Phe Phe Lys Gly Ala His Tyr Trp Arg Phe Pro Lys Asn Ser Ile 
    370                 375                 380                 


Lys Thr Glu Pro Asp Ala Pro Gln Pro Met Gly Pro Asn Trp Leu Asp 
385                 390                 395                 400 


Cys Pro Ala Pro Ser Ser Gly Pro Arg Ala Pro Arg Pro Pro Lys Ala 
                405                 410                 415     


Thr Pro Val Ser Glu Thr Cys Asp Cys Gln Cys Glu Leu Asn Gln Ala 
            420                 425                 430         


<210>  1596
<211>  483
<212>  PRT
<213>  Homo Sapiens

<400>  1596

Val Pro Leu Gln Ser Asn Arg Leu Gly Pro Thr Ser Arg Leu Arg Tyr 
1               5                   10                  15      


Ser Arg Phe Leu Asp Pro Ser Asn Val Ile Phe Leu Arg Trp Asp Phe 
            20                  25                  30          


Asp Leu Glu Ala Glu Ile Ile Ser Phe Glu Leu Gln Val Arg Thr Ala 
        35                  40                  45              


Gly Trp Val Gly Phe Gly Val Thr Asn Arg Tyr Thr Asn Val Gly Ser 
    50                  55                  60                  


Asp Leu Val Val Gly Gly Val Leu Pro Asn Gly Asn Val Tyr Phe Ser 
65                  70                  75                  80  


Asp Gln His Leu Val Glu Glu Asp Thr Leu Lys Glu Asp Gly Ser Gln 
                85                  90                  95      


Asp Ala Glu Leu Leu Gly Leu Thr Glu Asp Ala Val Tyr Thr Thr Met 
            100                 105                 110         


His Phe Ser Arg Pro Phe Arg Ser Cys Asp Pro His Asp Leu Asp Ile 
        115                 120                 125             


Thr Ser Asn Thr Val Arg Val Leu Ala Ala Tyr Gly Leu Asp Asp Thr 
    130                 135                 140                 


Leu Lys Leu Tyr Arg Glu Arg Thr Phe Val Lys Ser Ile Phe Leu Leu 
145                 150                 155                 160 


Gln Val Val His Pro Asp Asp Leu Asp Val Pro Glu Asp Thr Ile Ile 
                165                 170                 175     


His Asp Leu Glu Ile Thr Asn Phe Leu Ile Pro Glu Asp Asp Thr Thr 
            180                 185                 190         


Tyr Ala Cys Thr Phe Leu Pro Leu Pro Ile Val Ser Glu Lys His His 
        195                 200                 205             


Ile Tyr Lys Phe Glu Pro Lys Leu Val Tyr His Asn Glu Thr Thr Val 
    210                 215                 220                 


His His Ile Leu Val Tyr Ala Cys Gly Asn Ala Ser Val Leu Pro Thr 
225                 230                 235                 240 


Gly Ile Ser Asp Cys Tyr Gly Ala Asp Pro Ala Phe Ser Leu Cys Ser 
                245                 250                 255     


Gln Val Ile Val Gly Ser Ala Val Gly Gly Thr Ser Tyr Gln Phe Pro 
            260                 265                 270         


Asp Asp Val Gly Val Ser Ile Gly Thr Pro Leu Asp Pro Gln Trp Ile 
        275                 280                 285             


Leu Glu Ile His Tyr Ser Asn Phe Asn Asn Leu Pro Gly Val Tyr Asp 
    290                 295                 300                 


Ser Ser Gly Ile Arg Val Tyr Tyr Thr Ser Gln Leu Cys Lys Tyr Asp 
305                 310                 315                 320 


Thr Asp Val Leu Gln Leu Gly Phe Phe Thr Phe Pro Ile His Phe Ile 
                325                 330                 335     


Pro Pro Gly Ala Glu Ser Phe Met Ser Tyr Gly Leu Cys Arg Thr Glu 
            340                 345                 350         


Lys Phe Glu Glu Met Asn Gly Ala Pro Met Pro Asp Ile Gln Val Tyr 
        355                 360                 365             


Gly Tyr Leu Leu His Thr His Leu Ala Gly Arg Ala Leu Gln Ala Val 
    370                 375                 380                 


Gln Tyr Arg Asn Gly Thr Gln Leu Arg Lys Ile Cys Lys Asp Asp Ser 
385                 390                 395                 400 


Tyr Asp Phe Asn Leu Gln Glu Thr Arg Asp Leu Pro Ser Arg Val Glu 
                405                 410                 415     


Ile Lys Pro Gly Asp Glu Leu Leu Val Glu Cys His Tyr Gln Thr Leu 
            420                 425                 430         


Asp Arg Asp Ser Met Thr Phe Gly Gly Pro Ser Thr Ile Asn Glu Met 
        435                 440                 445             


Cys Leu Ile Phe Leu Phe Tyr Tyr Pro Gln Asn Asn Ile Ser Ser Cys 
    450                 455                 460                 


Met Gly Tyr Pro Asp Ile Ile Tyr Val Ala His Glu Leu Gly Glu Glu 
465                 470                 475                 480 


Ala Ser Glu 
            


<210>  1597
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  1597

Ser Lys Cys Tyr Phe Gln Ala Gln Ala Pro Cys His Tyr Glu Gly Lys 
1               5                   10                  15      


Tyr Phe Thr Leu Gly Glu Ser Trp Leu Arg Lys Asp Cys Phe His Cys 
            20                  25                  30          


Thr Cys Leu His Pro Val Gly Val Gly Cys Cys Asp Thr Ser Gln His 
        35                  40                  45              


Pro Ile Asp Phe Pro Ala Gly Cys Glu Val Arg Gln Glu Ala Gly Thr 
    50                  55                  60                  


Cys Gln Phe Ser Leu Val Gln Lys Ser Asp Pro Arg Leu Pro Cys Lys 
65                  70                  75                  80  


Gly Gly Gly Pro Asp Pro Glu Trp Gly Ser Ala Asn Thr Pro Val Pro 
                85                  90                  95      


Gly Ala Pro Ala Pro His Ser Ser 
            100                 


<210>  1598
<211>  419
<212>  PRT
<213>  Homo Sapiens

<400>  1598

Thr Thr Phe Gln Glu Tyr Gln Lys Thr Gly Glu Leu Ser Thr Ser Asp 
1               5                   10                  15      


His Ile Phe Pro Leu Thr Pro Gly Leu Val Tyr Ser Ile Pro Phe Asp 
            20                  25                  30          


His Ile Val Leu His Ser Gly Gln Arg Pro Pro Glu Leu Pro Lys Ser 
        35                  40                  45              


Thr Glu Ile His Glu Gln Lys Arg His Cys Asn Thr Thr Arg His Ser 
    50                  55                  60                  


Lys Pro Thr Asp Lys Pro Thr Gly Asn Ser Lys Thr Ile Asp His Lys 
65                  70                  75                  80  


Ser Ser Thr Asp Asn His Glu Ala Pro Pro Thr Ser Glu Glu Asn Ser 
                85                  90                  95      


Ser Asn Gln Gly Lys Asp Pro Met Ile Arg Asn Gln Arg Ser Val Asp 
            100                 105                 110         


Pro Ala Asp Ser Thr Thr Thr His Lys Glu Ser Ala Gly Lys Lys His 
        115                 120                 125             


Ile Thr Pro Ala Pro Lys Ser Lys Ile Asn Cys Arg Lys Ser Thr Thr 
    130                 135                 140                 


Gly Lys Ser Thr Val Thr Arg Lys Ser Asp Lys Thr Gly Arg Pro Leu 
145                 150                 155                 160 


Glu Lys Ser Met Ser Thr Leu Asp Lys Thr Ser Thr Ser Ser His Lys 
                165                 170                 175     


Thr Thr Thr Ser Phe His Asn Ser Gly Asn Ser Gln Thr Lys Gln Lys 
            180                 185                 190         


Ser Thr Ser Phe Pro Glu Lys Ile Thr Ala Ala Ser Lys Thr Thr Tyr 
        195                 200                 205             


Lys Thr Thr Gly Thr Pro Glu Glu Ser Glu Lys Thr Glu Asp Ser Arg 
    210                 215                 220                 


Thr Thr Val Ala Ser Asp Lys Leu Leu Thr Lys Thr Thr Lys Asn Ile 
225                 230                 235                 240 


Gln Glu Thr Ile Ser Ala Asn Glu Leu Thr Gln Ser Leu Ala Glu Pro 
                245                 250                 255     


Thr Glu His Gly Gly Arg Thr Ala Asn Glu Asn Asn Thr Pro Ser Pro 
            260                 265                 270         


Ala Glu Pro Thr Glu Asn Arg Glu Arg Thr Ala Asn Glu Asn Lys Lys 
        275                 280                 285             


Thr Ile Cys Thr Lys Gly Lys Asn Thr Pro Val Pro Glu Lys Pro Thr 
    290                 295                 300                 


Glu Asn Leu Gly Asn Thr Thr Leu Thr Thr Glu Thr Ile Lys Ala Pro 
305                 310                 315                 320 


Val Lys Ser Thr Glu Asn Pro Glu Lys Thr Ala Ala Val Thr Lys Thr 
                325                 330                 335     


Ile Lys Pro Ser Val Lys Val Thr Gly Asp Lys Ser Leu Thr Thr Thr 
            340                 345                 350         


Ser Ser His Leu Asn Lys Thr Glu Val Thr His Gln Val Pro Thr Gly 
        355                 360                 365             


Ser Phe Thr Leu Ile Thr Ser Arg Thr Lys Leu Ser Ser Ile Thr Ser 
    370                 375                 380                 


Glu Ala Thr Gly Asn Glu Ser His Pro Tyr Leu Asn Lys Asp Gly Ser 
385                 390                 395                 400 


Gln Lys Gly Ile His Ala Gly Gln Met Gly Glu Asn Asp Ser Phe Pro 
                405                 410                 415     


Ala Trp Ala 
            


<210>  1599
<211>  331
<212>  PRT
<213>  Homo Sapiens

<400>  1599

Ser Pro Pro Ala Ala Pro Arg Phe Asn Val Ser Leu Asp Ser Val Pro 
1               5                   10                  15      


Glu Leu Arg Trp Leu Pro Val Leu Arg His Tyr Asp Leu Asp Leu Val 
            20                  25                  30          


Arg Ala Ala Met Ala Gln Val Ile Gly Asp Arg Val Pro Lys Trp Val 
        35                  40                  45              


His Val Leu Ile Gly Lys Val Val Leu Glu Leu Glu Arg Phe Leu Pro 
    50                  55                  60                  


Gln Pro Phe Thr Gly Glu Ile Arg Gly Met Cys Asp Phe Met Asn Leu 
65                  70                  75                  80  


Ser Leu Ala Asp Cys Leu Leu Val Asn Leu Ala Tyr Glu Ser Ser Val 
                85                  90                  95      


Phe Cys Thr Ser Ile Val Ala Gln Asp Ser Arg Gly His Ile Tyr His 
            100                 105                 110         


Gly Arg Asn Leu Asp Tyr Pro Phe Gly Asn Val Leu Arg Lys Leu Thr 
        115                 120                 125             


Val Asp Val Gln Phe Leu Lys Asn Gly Gln Ile Ala Phe Thr Gly Thr 
    130                 135                 140                 


Thr Phe Ile Gly Tyr Val Gly Leu Trp Thr Gly Gln Ser Pro His Lys 
145                 150                 155                 160 


Phe Thr Val Ser Gly Asp Glu Arg Asp Lys Gly Trp Trp Trp Glu Asn 
                165                 170                 175     


Ala Ile Ala Ala Leu Phe Arg Arg His Ile Pro Val Ser Trp Leu Ile 
            180                 185                 190         


Arg Ala Thr Leu Ser Glu Ser Glu Asn Phe Glu Ala Ala Val Gly Lys 
        195                 200                 205             


Leu Ala Lys Thr Pro Leu Ile Ala Asp Val Tyr Tyr Ile Val Gly Gly 
    210                 215                 220                 


Thr Ser Pro Arg Glu Gly Val Val Ile Thr Arg Asn Arg Asp Gly Pro 
225                 230                 235                 240 


Ala Asp Ile Trp Pro Leu Asp Pro Leu Asn Gly Ala Trp Phe Arg Val 
                245                 250                 255     


Glu Thr Asn Tyr Asp His Trp Lys Pro Ala Pro Lys Glu Asp Asp Arg 
            260                 265                 270         


Arg Thr Ser Ala Ile Lys Ala Leu Asn Ala Thr Gly Gln Ala Asn Leu 
        275                 280                 285             


Ser Leu Glu Ala Leu Phe Gln Ile Leu Ser Val Val Pro Val Tyr Asn 
    290                 295                 300                 


Asn Phe Thr Ile Tyr Thr Thr Val Met Ser Ala Gly Ser Pro Asp Lys 
305                 310                 315                 320 


Tyr Met Thr Arg Ile Arg Asn Pro Ser Arg Lys 
                325                 330     


<210>  1600
<211>  165
<212>  PRT
<213>  Homo Sapiens

<400>  1600

Ala Ala Pro Pro Pro Ile Asn Lys Leu Ala Leu Phe Pro Asp Lys Ser 
1               5                   10                  15      


Ala Trp Cys Glu Ala Lys Asn Ile Thr Gln Ile Val Gly His Ser Gly 
            20                  25                  30          


Cys Glu Ala Lys Ser Ile Gln Asn Arg Ala Cys Leu Gly Gln Cys Phe 
        35                  40                  45              


Ser Tyr Ser Val Pro Asn Thr Phe Pro Gln Ser Thr Glu Ser Leu Val 
    50                  55                  60                  


His Cys Asp Ser Cys Met Pro Ala Gln Ser Met Trp Glu Ile Val Thr 
65                  70                  75                  80  


Leu Glu Cys Pro Gly His Glu Glu Val Pro Arg Val Asp Lys Leu Val 
                85                  90                  95      


Glu Lys Ile Leu His Cys Ser Cys Gln Ala Cys Gly Lys Glu Pro Ser 
            100                 105                 110         


His Glu Gly Leu Ser Val Tyr Val Gln Gly Glu Asp Gly Pro Gly Ser 
        115                 120                 125             


Gln Pro Gly Thr His Pro His Pro His Pro His Pro His Pro Gly Gly 
    130                 135                 140                 


Gln Thr Pro Glu Pro Glu Asp Pro Pro Gly Ala Pro His Thr Glu Glu 
145                 150                 155                 160 


Glu Gly Ala Glu Asp 
                165 


<210>  1601
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  1601

Thr Lys Lys Gly Thr Glu Lys Gln Thr Thr Ser Glu Thr Gln Lys Ser 
1               5                   10                  15      


Val Gln Cys Gly Thr Trp Thr Lys His Ala Glu Gly Gly Ile Phe Thr 
            20                  25                  30          


Ser Pro Asn Tyr Pro Ser Lys Tyr Pro Pro Asp Arg Glu Cys Ile Tyr 
        35                  40                  45              


Ile Ile Glu Ala Ala Pro Arg Gln Cys Ile Glu Leu Tyr Phe Asp Glu 
    50                  55                  60                  


Lys Tyr Ser Ile Glu Pro Ser Trp Glu Cys Lys Phe Asp His Ile Glu 
65                  70                  75                  80  


Val Arg Asp Gly Pro Phe Gly Phe Ser Pro Ile Ile Gly Arg Phe Cys 
                85                  90                  95      


Gly Gln Gln Asn Pro Pro Val Ile Lys Ser Ser Gly Arg Phe Leu Trp 
            100                 105                 110         


Ile Lys Phe Phe Ala Asp Gly Glu Leu Glu Ser Met Gly Phe Ser Ala 
        115                 120                 125             


Arg Tyr Asn Phe Thr Pro Asp Pro Asp Phe Lys Asp Leu Gly Ala Leu 
    130                 135                 140                 


Lys Pro Leu Pro Ala Cys Glu Phe Glu Met Gly Gly Ser Glu Gly Ile 
145                 150                 155                 160 


Val Glu Ser Ile Gln Ile Met Lys Glu Gly Lys Ala Thr Ala Ser Glu 
                165                 170                 175     


Ala Val Asp Cys Lys Trp Tyr Ile Arg Ala Pro Pro Arg Ser Lys Ile 
            180                 185                 190         


Tyr Leu Arg Phe Leu Asp Tyr Glu Met Gln Asn Ser Asn Glu Cys Lys 
        195                 200                 205             


Arg Asn Phe Val Ala Val Tyr Asp Gly Ser Ser Ser Val Glu Asp Leu 
    210                 215                 220                 


Lys Ala Lys Phe Cys Ser Thr Val Ala Asn Asp Val Met Leu Arg Thr 
225                 230                 235                 240 


Gly Leu Gly Val Ile Arg Met Trp Ala Asp Glu Gly Ser Arg Asn Ser 
                245                 250                 255     


Arg Phe Gln Met Leu Phe Thr Ser Phe Gln Glu Pro Pro Cys Glu Gly 
            260                 265                 270         


Asn Thr Phe Phe Cys His Ser Asn Met Cys Ile Asn Asn Thr Leu Val 
        275                 280                 285             


Cys Asn Gly Leu Gln Asn Cys Val Tyr Pro Trp Asp Glu Asn His Cys 
    290                 295                 300                 


Lys Glu Lys Arg Lys Thr Ser Leu Leu Asp Gln Leu Thr Asn Thr Ser 
305                 310                 315                 320 


Gly Thr 
        


<210>  1602
<211>  276
<212>  PRT
<213>  Homo Sapiens

<400>  1602

Ala Val Thr Arg Cys Gly Phe Ala Thr Arg Gly Val Ala Gly Pro Gly 
1               5                   10                  15      


Pro Ile Gly Arg Glu Pro Asp Pro Asp Ser Asp Trp Glu Pro Glu Glu 
            20                  25                  30          


Arg Glu Leu Gln Glu Val Glu Ser Thr Leu Lys Arg Gln Lys Gln Ala 
        35                  40                  45              


Ile Arg Phe Gln Lys Ile Arg Arg Gln Met Glu Ala Pro Gly Ala Pro 
    50                  55                  60                  


Pro Arg Thr Leu Thr Trp Glu Ala Met Glu Gln Ile Arg Tyr Leu His 
65                  70                  75                  80  


Glu Glu Phe Pro Glu Ser Trp Ser Val Pro Arg Leu Ala Glu Gly Phe 
                85                  90                  95      


Asp Val Ser Thr Asp Val Ile Arg Arg Val Leu Lys Ser Lys Phe Leu 
            100                 105                 110         


Pro Thr Leu Glu Gln Lys Leu Lys Gln Asp Gln Lys Val Leu Lys Lys 
        115                 120                 125             


Ala Gly Leu Ala His Ser Leu Gln His Leu Arg Gly Ser Gly Asn Thr 
    130                 135                 140                 


Ser Lys Leu Leu Pro Ala Gly His Ser Val Ser Gly Ser Leu Leu Met 
145                 150                 155                 160 


Pro Gly His Glu Ala Ser Ser Lys Asp Pro Asn His Ser Thr Ala Leu 
                165                 170                 175     


Lys Val Ile Glu Ser Asp Thr His Arg Thr Asn Thr Pro Arg Arg Arg 
            180                 185                 190         


Lys Gly Arg Asn Lys Glu Ile Gln Asp Leu Glu Glu Ser Phe Val Pro 
        195                 200                 205             


Val Ala Ala Pro Leu Gly His Pro Arg Glu Leu Gln Lys Tyr Ser Ser 
    210                 215                 220                 


Asp Ser Glu Ser Pro Arg Gly Thr Gly Ser Gly Ala Leu Pro Ser Gly 
225                 230                 235                 240 


Gln Lys Leu Glu Glu Leu Lys Ala Glu Glu Pro Asp Asn Phe Ser Ser 
                245                 250                 255     


Lys Val Val Gln Arg Gly Arg Glu Phe Phe Asp Ser Asn Gly Asn Phe 
            260                 265                 270         


Leu Tyr Arg Ile 
        275     


<210>  1603
<211>  117
<212>  PRT
<213>  Homo Sapiens

<400>  1603

Met Pro Gly Asp Ser Ser Pro Gly Thr Leu Pro Leu Trp Asp Ala Ser 
1               5                   10                  15      


Leu Ser Pro Pro Leu Gly Pro Asp Pro Gly Gly Phe Ser Arg Ala Ser 
            20                  25                  30          


His Ala Gly Asp Lys Ser Arg Pro Pro Ala Pro Glu Leu Gly Ser Pro 
        35                  40                  45              


Gly Ala Val Arg Pro Arg Val Gly Ser Cys Ala Pro Gly Pro Met Glu 
    50                  55                  60                  


Leu Arg Val Ser Asn Thr Ser Cys Glu Asn Gly Ser Leu Leu His Leu 
65                  70                  75                  80  


Tyr Cys Ser Ser Gln Glu Val Leu Cys Gln Ile Val Asn Asp Leu Ser 
                85                  90                  95      


Pro Glu Val Pro Ser Asn Ala Thr Phe His Ser Trp Gln Glu Arg Ile 
            100                 105                 110         


Arg Gln Asn Tyr Gly 
        115         


<210>  1604
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  1604

Ser Glu Gly Arg Lys Thr Trp Arg Arg Arg Gly Gln Gln Pro Pro Pro 
1               5                   10                  15      


Pro Pro Arg Thr Glu Ala Ala Pro Ala Ala Gly Gln Pro Val Glu Ser 
            20                  25                  30          


Phe Pro Leu Asp Phe Thr Ala Val Glu Gly Asn Met Asp Ser Phe Met 
        35                  40                  45              


Ala Gln Val Lys Ser Leu Ala Gln Ser Leu Tyr Pro Cys Ser Ala Gln 
    50                  55                  60                  


Gln Leu Asn Glu Asp Leu Arg Leu His Leu Leu Leu Asn Thr Ser Val 
65                  70                  75                  80  


Thr Cys Asn Asp Gly Ser Pro Ala Gly Tyr Tyr Leu Lys Glu Ser Arg 
                85                  90                  95      


Gly Ser Arg Arg Trp Leu Leu Phe Leu Glu Gly Gly Trp Tyr Cys Phe 
            100                 105                 110         


Asn Arg Glu Asn Cys Asp Ser Arg Tyr Asp Thr Met Arg Arg Leu Met 
        115                 120                 125             


Ser Ser Arg Asp Trp Pro Arg Thr Arg Thr Gly Thr Gly Ile Leu Ser 
    130                 135                 140                 


Ser Gln Pro Glu Glu Asn Pro Tyr Trp Trp Asn Ala Asn Met Val Phe 
145                 150                 155                 160 


Ile Pro Tyr Cys Ser Ser Asp Val Trp Ser Gly Ala Ser Ser Lys Ser 
                165                 170                 175     


Glu Lys Asn Glu Tyr Ala Phe Met Gly Ala Leu Ile Ile Gln Glu Val 
            180                 185                 190         


Val Arg Glu Leu Leu Gly Arg Gly Leu Ser Gly Ala Lys Val Leu Leu 
        195                 200                 205             


Leu Ala Gly Ser Ser Ala Gly Gly Thr Gly Val Leu Leu Asn Val Asp 
    210                 215                 220                 


Arg Val Ala Glu Gln Leu Glu Lys Leu Gly Tyr Pro Ala Ile Gln Val 
225                 230                 235                 240 


Arg Gly Leu Ala Asp Ser Gly Trp Phe Leu Asp Asn Lys Gln Tyr Arg 
                245                 250                 255     


His Thr Asp Cys Val Asp Thr Ile Thr Cys Ala Pro Thr Glu Ala Ile 
            260                 265                 270         


Arg Arg Gly Ile Arg Tyr Trp Asn Gly Val Val Pro Glu Arg Cys Arg 
        275                 280                 285             


Arg Gln Phe Gln Glu Gly Glu Glu Trp Asn Cys Phe Phe Gly Tyr Lys 
    290                 295                 300                 


Val Tyr Pro Thr Leu Arg Cys Pro Val Phe Val Val Gln Trp Leu Phe 
305                 310                 315                 320 


Asp Glu Ala Gln Leu Thr Val Asp Asn Val His Leu Thr Gly Gln Pro 
                325                 330                 335     


Val Gln Glu Gly Leu Arg Leu Tyr Ile Gln Asn Leu Gly Arg Glu Leu 
            340                 345                 350         


Arg His Thr Leu Lys Asp Val Pro Ala Ser Phe Ala Pro Ala Cys Leu 
        355                 360                 365             


Ser His Glu Ile Ile Ile Arg Ser His Trp Thr Asp Val Gln Val Lys 
    370                 375                 380                 


Gly Thr Ser Leu Pro Arg Ala Leu His Cys Trp Asp Arg Ser Leu His 
385                 390                 395                 400 


Asp Ser His Lys Ala Ser Lys Thr Pro Leu Lys Gly Cys Pro Val His 
                405                 410                 415     


Leu Val Asp Ser Cys Pro Trp Pro His Cys Asn Pro Ser Cys Pro Thr 
            420                 425                 430         


Val Arg Asp Gln Phe Thr Gly Gln Glu Met Asn Val Ala Gln Phe Leu 
        435                 440                 445             


Met His Met Gly Phe Asp Met Gln Thr Val Ala Gln Pro Gln Gly Leu 
    450                 455                 460                 


Glu Pro Ser Glu Leu Leu Gly Met Leu Ser Asn Gly Ser 
465                 470                 475         


<210>  1605
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  1605

Gly Arg Ile Val Arg Gly Gln Thr Gln Asp Ser Leu Ser Leu His Asn 
1               5                   10                  15      


Ile Thr Phe Cys Arg Asp Arg Tyr Ala Glu Trp Gln Thr Val Ala Gln 
            20                  25                  30          


Cys Pro Val Pro Gln Phe Ser Gly Lys Glu Pro Ser Ala Trp Lys Trp 
        35                  40                  45              


Ile Leu Gly Pro Val Val Leu Tyr Ala Cys Glu Arg Ile Ile Arg Phe 
    50                  55                  60                  


Trp Arg Phe Gln Gln Glu Val Val Ile Thr Lys Val Val Ser His Pro 
65                  70                  75                  80  


Ser Gly Val Leu Glu Leu His Met Lys Lys Arg Gly Phe Lys Met Ala 
                85                  90                  95      


Pro Gly Gln Tyr Ile Leu Val Gln Cys Pro Ala Ile Ser Ser Leu Glu 
            100                 105                 110         


Trp His Pro Phe Thr Leu Thr Ser Ala Pro Gln Glu Asp Phe Phe Ser 
        115                 120                 125             


Val His Ile Arg Ala Ala Gly Asp Trp Thr Ala Ala Leu Leu Glu Ala 
    130                 135                 140                 


Phe Gly Ala Glu Gly Gln Ala Leu Gln Glu Pro Trp Ser Leu Pro Arg 
145                 150                 155                 160 


Leu Ala Val Asp Gly Pro Phe Gly Thr Ala Leu Thr Asp 
                165                 170             


<210>  1606
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  1606

Gln Pro Thr Pro Val Ile Asn Ser Leu Ala Val Tyr Arg His Arg Glu 
1               5                   10                  15      


Thr Asp Phe Gly Val Gly Val Arg Asp His Pro Gly Gln His Gly Lys 
            20                  25                  30          


Thr Pro Ser Pro Gln Lys Leu Asp Asn Leu Ile Ile Ile Ile Ile Gly 
        35                  40                  45              


Phe Leu Arg Arg Asp Thr Phe Thr Ile Leu Phe Cys Thr Ser Tyr Leu 
    50                  55                  60                  


Cys Val Ser Phe Leu Lys Thr Ile Phe Trp Ser Arg Asn Gly His Asp 
65                  70                  75                  80  


Gly Ser Thr Asp Val Gln Gln Arg Ala Trp Arg Ser Asn Arg Ser Arg 
                85                  90                  95      


Gln Lys Gly Leu Arg Ser Ile Cys Met His Thr Lys Lys Arg Val Ser 
            100                 105                 110         


Ser Phe Arg Gly Asn Lys Ile Gly Leu Lys Asp Val Ile Thr Leu Arg 
        115                 120                 125             


Arg His Val Glu Thr Lys Val Arg Ala Lys Ile Arg Lys Arg Lys Val 
    130                 135                 140                 


Thr Thr Lys Ile Asn Arg His Asp Lys Ile Asn Gly Lys Arg Lys Thr 
145                 150                 155                 160 


Ala Arg Lys Gln Lys Met Phe Gln Arg Ala Gln Glu Leu Arg Arg Arg 
                165                 170                 175     


Ala Glu Asp Tyr His Lys Cys Lys Ile Pro Pro Ser Ala Arg Lys Pro 
            180                 185                 190         


Leu Cys Asn Trp Val Arg Met Ala Ala Ala Glu His Arg His Ser Ser 
        195                 200                 205             


Gly Leu Pro Cys Trp Pro Tyr Leu Thr Ala Glu Ala Leu Lys Asn Arg 
    210                 215                 220                 


Met Gly Arg Gln Pro Pro Pro Pro Thr Gln Gln His Ser Ile Thr Asp 
225                 230                 235                 240 


Asn Ser Leu Ser Leu Lys Thr Pro Pro Glu Cys Leu Leu His Pro Leu 
                245                 250                 255     


Pro Pro Ser Val Asp Asp Asn Ile Lys Glu Cys Pro Leu Ala Pro Leu 
            260                 265                 270         


Pro Pro Ser Val Asp Asp Asn Leu Lys Glu Tyr Leu Leu Val Pro Leu 
        275                 280                 285             


Pro Pro Ser Pro Leu Pro Pro Ser Val Asp Asp Asn Leu Lys Asp Cys 
    290                 295                 300                 


Leu Phe Val Pro Leu Pro Pro Ser Pro Leu Pro Pro Ser Val Asp Asp 
305                 310                 315                 320 


Asn Leu Lys Thr Pro Pro Leu Ala Thr Gln Glu Ala Glu Ala Glu Lys 
                325                 330                 335     


Pro Pro Lys Pro Lys Arg Trp Arg Val Asp Glu Val Glu Gln Ser Pro 
            340                 345                 350         


Lys Pro Lys Arg Arg Arg Ala Asp Glu Val Glu Gln Ser Pro Lys Pro 
        355                 360                 365             


Lys Arg Gln Arg Glu Ala Glu Ala Gln Gln Leu Pro Lys Pro Lys Arg 
    370                 375                 380                 


Arg Arg Leu Ser Lys Leu Arg Thr Arg His Cys Thr Gln Ala Trp Ala 
385                 390                 395                 400 


Ile Arg Ile Asn Pro Trp Val Glu Lys Lys Lys Lys Ile Lys Lys Gln 
                405                 410                 415     


Asn Lys Thr His Ala Pro Lys Thr Asn 
            420                 425 


<210>  1607
<211>  396
<212>  PRT
<213>  Homo Sapiens

<400>  1607

Gln Pro Thr Pro Val Ile Asn Ser Leu Ala Val Tyr Arg His Arg Glu 
1               5                   10                  15      


Thr Asp Phe Gly Val Gly Val Arg Asp His Pro Gly Gln His Gly Lys 
            20                  25                  30          


Thr Pro Ser Pro Gln Lys Leu Asp Asn Leu Ile Ile Ile Ile Ile Gly 
        35                  40                  45              


Phe Leu Arg Arg Tyr Thr Phe Asn Val Leu Phe Cys Thr Ser Cys Leu 
    50                  55                  60                  


Cys Val Ser Phe Leu Lys Thr Ile Phe Trp Ser Arg Asn Gly His Asp 
65                  70                  75                  80  


Gly Ser Met Asp Val Gln Gln Arg Ala Trp Arg Ser Asn Arg Ser Arg 
                85                  90                  95      


Gln Lys Gly Leu Arg Ser Ile Cys Met His Thr Lys Lys Arg Val Ser 
            100                 105                 110         


Ser Phe Arg Gly Asn Lys Ile Gly Leu Lys Asp Val Ile Thr Leu Arg 
        115                 120                 125             


Arg His Val Glu Thr Lys Val Arg Ala Lys Ile Arg Lys Arg Lys Val 
    130                 135                 140                 


Thr Thr Lys Ile Asn Arg His Asp Lys Ile Asn Gly Lys Arg Lys Thr 
145                 150                 155                 160 


Ala Arg Lys Gln Lys Met Phe Gln Arg Ala Gln Glu Leu Arg Arg Arg 
                165                 170                 175     


Ala Glu Asp Tyr His Lys Cys Lys Ile Pro Pro Ser Ala Arg Lys Pro 
            180                 185                 190         


Leu Cys Asn Trp Val Arg Met Ala Ala Ala Glu His Cys His Ser Ser 
        195                 200                 205             


Gly Leu Pro Tyr Trp Leu Tyr Leu Thr Ala Glu Thr Leu Lys Asn Arg 
    210                 215                 220                 


Met Gly Arg Gln Pro Pro Pro Pro Thr Gln Gln His Ser Ile Thr Asp 
225                 230                 235                 240 


Asn Ser Leu Ser Leu Lys Thr Pro Pro Glu Cys Leu Leu Thr Pro Leu 
                245                 250                 255     


Pro Pro Ser Val Asp Asp Asn Ile Lys Glu Cys Pro Leu Ala Pro Leu 
            260                 265                 270         


Pro Pro Ser Pro Leu Pro Pro Ser Val Asp Asp Asn Leu Lys Glu Cys 
        275                 280                 285             


Leu Phe Val Pro Leu Pro Pro Ser Pro Leu Pro Pro Ser Val Asp Asp 
    290                 295                 300                 


Asn Leu Lys Glu Cys Leu Phe Val Pro Leu Pro Pro Ser Pro Leu Pro 
305                 310                 315                 320 


Pro Ser Val Asp Asp Asn Leu Lys Thr Pro Pro Leu Ala Thr Gln Glu 
                325                 330                 335     


Ala Glu Val Glu Lys Pro Pro Lys Pro Lys Arg Trp Arg Val Asp Glu 
            340                 345                 350         


Val Glu Gln Ser Pro Lys Pro Lys Arg Gln Arg Glu Ala Glu Ala Gln 
        355                 360                 365             


Gln Leu Pro Lys Pro Lys Arg Arg Arg Leu Ser Lys Leu Arg Thr Arg 
    370                 375                 380                 


His Cys Thr Gln Ala Trp Ala Ile Arg Ile Asn Pro 
385                 390                 395     


<210>  1608
<211>  108
<212>  PRT
<213>  Homo Sapiens

<400>  1608

His Pro Leu Gly Ser Pro Gly Ser Ala Ser Asp Leu Glu Thr Ser Gly 
1               5                   10                  15      


Leu Gln Glu Gln Arg Asn His Leu Gln Gly Lys Leu Ser Glu Leu Gln 
            20                  25                  30          


Val Glu Gln Thr Ser Leu Glu Pro Leu Gln Glu Ser Pro Arg Pro Thr 
        35                  40                  45              


Gly Val Trp Lys Ser Arg Glu Val Ala Thr Glu Gly Ile Arg Gly His 
    50                  55                  60                  


Arg Lys Met Val Leu Tyr Thr Leu Arg Ala Pro Arg Ser Pro Lys Met 
65                  70                  75                  80  


Val Gln Gly Ser Gly Cys Phe Gly Arg Lys Met Asp Arg Ile Ser Ser 
                85                  90                  95      


Ser Ser Gly Leu Gly Cys Lys Val Leu Arg Arg His 
            100                 105             


<210>  1609
<211>  455
<212>  PRT
<213>  Homo Sapiens

<400>  1609

Gly Gly Val Gly Gly Gly Gly Gly Gly Ala Gly Ile Gly Gly Gly Arg 
1               5                   10                  15      


Gln Glu Arg Glu Ala Leu Pro Pro Gln Lys Ile Glu Val Leu Val Leu 
            20                  25                  30          


Leu Pro Gln Asp Asp Ser Tyr Leu Phe Ser Leu Thr Arg Val Arg Pro 
        35                  40                  45              


Ala Ile Glu Tyr Ala Leu Arg Ser Val Glu Gly Asn Gly Thr Gly Arg 
    50                  55                  60                  


Arg Leu Leu Pro Pro Gly Thr Arg Phe Gln Val Ala Tyr Glu Asp Ser 
65                  70                  75                  80  


Asp Cys Gly Asn Arg Ala Leu Phe Ser Leu Val Asp Arg Val Ala Ala 
                85                  90                  95      


Ala Arg Gly Ala Lys Pro Asp Leu Ile Leu Gly Pro Val Cys Glu Tyr 
            100                 105                 110         


Ala Ala Ala Pro Val Ala Arg Leu Ala Ser His Trp Asp Leu Pro Met 
        115                 120                 125             


Leu Ser Ala Gly Ala Leu Ala Ala Gly Phe Gln His Lys Asp Ser Glu 
    130                 135                 140                 


Tyr Ser His Leu Thr Arg Val Ala Pro Ala Tyr Ala Lys Met Gly Glu 
145                 150                 155                 160 


Met Met Leu Ala Leu Phe Arg His His His Trp Ser Arg Ala Ala Leu 
                165                 170                 175     


Val Tyr Ser Asp Asp Lys Leu Glu Arg Asn Cys Tyr Phe Thr Leu Glu 
            180                 185                 190         


Gly Val His Glu Val Phe Gln Glu Glu Gly Leu His Thr Ser Ile Tyr 
        195                 200                 205             


Ser Phe Asp Glu Thr Lys Asp Leu Asp Leu Glu Asp Ile Val Arg Asn 
    210                 215                 220                 


Ile Gln Ala Ser Glu Arg Val Val Ile Met Cys Ala Ser Ser Asp Thr 
225                 230                 235                 240 


Ile Arg Ser Ile Met Leu Val Ala His Arg His Gly Met Thr Ser Gly 
                245                 250                 255     


Asp Tyr Ala Phe Phe Asn Ile Glu Leu Phe Asn Ser Ser Ser Tyr Gly 
            260                 265                 270         


Asp Gly Ser Trp Lys Arg Gly Asp Lys His Asp Phe Glu Ala Lys Gln 
        275                 280                 285             


Ala Tyr Ser Ser Leu Gln Thr Val Thr Leu Leu Arg Thr Val Lys Pro 
    290                 295                 300                 


Glu Phe Glu Lys Phe Ser Met Glu Val Lys Ser Ser Val Glu Lys Gln 
305                 310                 315                 320 


Gly Leu Asn Met Glu Asp Tyr Val Asn Met Phe Val Glu Gly Phe His 
                325                 330                 335     


Asp Ala Ile Leu Leu Tyr Val Leu Ala Leu His Glu Val Leu Arg Ala 
            340                 345                 350         


Gly Tyr Ser Lys Lys Asp Gly Gly Lys Ile Ile Gln Gln Thr Trp Asn 
        355                 360                 365             


Arg Thr Phe Glu Gly Ile Ala Gly Gln Val Ser Ile Asp Ala Asn Gly 
    370                 375                 380                 


Asp Arg Tyr Gly Asp Phe Ser Val Ile Ala Met Thr Asp Val Glu Ala 
385                 390                 395                 400 


Gly Thr Gln Glu Val Ile Gly Asp Tyr Phe Gly Lys Glu Gly Arg Phe 
                405                 410                 415     


Glu Met Arg Pro Asn Val Lys Tyr Pro Trp Gly Pro Leu Lys Leu Arg 
            420                 425                 430         


Ile Asp Glu Asn Arg Ile Val Glu His Thr Asn Ser Ser Pro Cys Lys 
        435                 440                 445             


Ser Ser Gly Gly Leu Glu Glu 
    450                 455 


<210>  1610
<211>  89
<212>  PRT
<213>  Homo Sapiens

<400>  1610

Ala Gly Lys Cys Asp Ala Val Phe Lys Gly Phe Ser Asp Cys Leu Leu 
1               5                   10                  15      


Lys Leu Gly Asp Ser Met Ala Asn Tyr Pro Gln Gly Leu Asp Asp Lys 
            20                  25                  30          


Thr Asn Ile Lys Thr Val Cys Thr Tyr Trp Glu Asp Phe His Ser Cys 
        35                  40                  45              


Thr Val Thr Ala Leu Thr Asp Cys Gln Glu Gly Ala Lys Asp Met Trp 
    50                  55                  60                  


Asp Lys Leu Arg Lys Glu Ser Lys Asn Leu Asn Ile Gln Gly Ser Leu 
65                  70                  75                  80  


Phe Glu Leu Cys Gly Ser Gly Asn Gly 
                85                  


<210>  1611
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  1611

Ala Arg Leu Gly Ala Arg Pro Cys Gly Leu Arg Glu Leu Glu Val Arg 
1               5                   10                  15      


Val Ser Glu Leu Gly Leu Gly Tyr Ala Ser Asp Glu Thr Val Leu Phe 
            20                  25                  30          


Arg Tyr Cys Ala Gly Ala Cys Glu Ala Ala Ala Arg Val Tyr Asp Leu 
        35                  40                  45              


Gly Leu Arg Arg Leu Arg Gln Arg Arg Arg Leu Arg Arg Glu Arg Val 
    50                  55                  60                  


Arg Ala Gln Pro Cys Cys Arg Pro Thr Ala Tyr Glu Asp Glu Val Ser 
65                  70                  75                  80  


Phe Leu Asp Ala His Ser Arg Tyr His Thr Val His Glu Leu Ser Ala 
                85                  90                  95      


Arg Glu Cys Ala Cys Val 
            100         


<210>  1612
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  1612

Val Pro Leu Glu Arg Gly Ala Pro Asn Lys Glu Glu Thr Pro Ala Thr 
1               5                   10                  15      


Glu Ser Pro Asp Thr Gly Leu Tyr Tyr His Arg Tyr Leu Gln Glu Val 
            20                  25                  30          


Ile Asp Val Leu Glu Thr Asp Gly His Phe Arg Glu Lys Leu Gln Ala 
        35                  40                  45              


Ala Asn Ala Glu Asp Ile Lys Ser Gly Lys Leu Ser Arg Glu Leu Asp 
    50                  55                  60                  


Phe Val Ser His His Val Arg Thr Lys Leu Asp Glu Leu Lys Arg Gln 
65                  70                  75                  80  


Glu Val Ser Arg Leu Arg Met Leu Leu Lys Ala Lys Met Asp Ala Glu 
                85                  90                  95      


Gln Asp Pro Asn Val Gln Val Asp His Leu Asn Leu Leu Lys Gln Phe 
            100                 105                 110         


Glu His Leu Asp Pro Gln Asn Gln His Thr Phe Glu Ala Arg Asp Leu 
        115                 120                 125             


Glu Leu Leu Ile Gln Thr Ala Thr Arg Asp Leu Ala Gln Tyr Asp Ala 
    130                 135                 140                 


Ala His His Glu Glu Phe Lys Arg Tyr Glu Met Leu Lys Glu His Glu 
145                 150                 155                 160 


Arg Arg Arg Tyr Leu Glu Ser Leu Gly Glu Glu Gln Arg Lys Glu Ala 
                165                 170                 175     


Glu Arg Lys Leu Glu Glu Gln Gln Arg Arg His Arg Glu His Pro Lys 
            180                 185                 190         


Val Asn Val Pro Gly Ser Gln Ala Gln Leu Lys Glu Val Trp Glu Glu 
        195                 200                 205             


Leu Asp Gly Leu Asp Pro Asn Arg Phe Asn Pro Lys Thr Phe Phe Ile 
    210                 215                 220                 


Leu His Asp Ile Asn Ser Asp Gly Val Leu Asp Glu Gln Glu Leu Glu 
225                 230                 235                 240 


Ala Leu Phe Thr Lys Glu Leu Glu Lys Val Tyr Asp Pro Lys Asn Glu 
                245                 250                 255     


Glu Asp Asp Met Arg Glu Met Glu Glu Glu Arg Leu Arg Met Arg Glu 
            260                 265                 270         


His Val Met Lys Asn Val Asp Thr Asn Gln Asp Arg Leu Val Thr Leu 
        275                 280                 285             


Glu Glu Phe Leu Ala Ser Thr Gln Arg Lys Glu Phe Gly Asp Thr Gly 
    290                 295                 300                 


Glu Gly Trp Glu Thr Val Glu Met His Pro Ala Tyr Thr Glu Glu Glu 
305                 310                 315                 320 


Leu Arg Arg Phe Glu Glu Glu Leu Ala Ala Arg Glu Ala Glu Leu Asn 
                325                 330                 335     


Ala Lys Ala Gln Arg Leu Ser Gln Glu Thr Glu Ala Leu Gly Arg Ser 
            340                 345                 350         


Gln Gly Arg Leu Glu Ala Gln Lys Arg Glu Leu Gln Gln Ala Val Leu 
        355                 360                 365             


His Met Glu Gln Arg Lys Gln Gln Gln Gln Gln Gln Gln Gly His Lys 
    370                 375                 380                 


Ala Pro Ala Ala His Pro Glu Gly Gln Leu Lys Phe His Pro Asp Thr 
385                 390                 395                 400 


Asp Asp Val Pro Val Pro Ala Pro Ala Gly Asp Gln Lys Glu Val Asp 
                405                 410                 415     


Thr Ser Glu Lys Lys Leu Leu Glu Arg Leu Pro Glu Val Glu Val Pro 
            420                 425                 430         


Gln His Leu 
        435 


<210>  1613
<211>  396
<212>  PRT
<213>  Homo Sapiens

<400>  1613

Val Pro Ile Asp Ile Asp Lys Thr Lys Val Gln Asn Ile His Pro Val 
1               5                   10                  15      


Glu Ser Ala Lys Ile Glu Pro Pro Asp Thr Gly Leu Tyr Tyr Asp Glu 
            20                  25                  30          


Tyr Leu Lys Gln Val Ile Asp Val Leu Glu Thr Asp Lys His Phe Arg 
        35                  40                  45              


Glu Lys Leu Gln Lys Ala Asp Ile Glu Glu Ile Lys Ser Gly Arg Leu 
    50                  55                  60                  


Ser Lys Glu Leu Asp Leu Val Ser His His Val Arg Thr Lys Leu Asp 
65                  70                  75                  80  


Glu Leu Lys Arg Gln Glu Val Gly Arg Leu Arg Met Leu Ile Lys Ala 
                85                  90                  95      


Lys Leu Asp Ser Leu Gln Asp Ile Gly Met Asp His Gln Ala Leu Leu 
            100                 105                 110         


Lys Gln Phe Asp His Leu Asn His Leu Asn Pro Asp Lys Phe Glu Ser 
        115                 120                 125             


Thr Asp Leu Asp Met Leu Ile Lys Ala Ala Thr Ser Asp Leu Glu His 
    130                 135                 140                 


Tyr Asp Lys Thr Arg His Glu Glu Phe Lys Lys Tyr Glu Met Met Lys 
145                 150                 155                 160 


Glu His Glu Arg Arg Glu Tyr Leu Lys Thr Leu Asn Glu Glu Lys Arg 
                165                 170                 175     


Lys Glu Glu Glu Ser Lys Phe Glu Glu Met Lys Lys Lys His Glu Asn 
            180                 185                 190         


His Pro Lys Val Asn His Pro Gly Ser Lys Asp Gln Leu Lys Glu Val 
        195                 200                 205             


Trp Glu Glu Thr Asp Gly Leu Asp Pro Asn Asp Phe Asp Pro Lys Thr 
    210                 215                 220                 


Phe Phe Lys Leu His Asp Val Asn Ser Asp Gly Phe Leu Asp Glu Gln 
225                 230                 235                 240 


Glu Leu Glu Ala Leu Phe Thr Lys Glu Leu Glu Lys Val Tyr Asp Pro 
                245                 250                 255     


Lys Asn Glu Glu Asp Asp Met Val Glu Met Glu Glu Glu Arg Leu Arg 
            260                 265                 270         


Met Arg Glu His Val Met Asn Glu Val Asp Thr Asn Lys Asp Arg Leu 
        275                 280                 285             


Val Thr Leu Glu Glu Phe Leu Lys Ala Thr Glu Lys Lys Glu Phe Leu 
    290                 295                 300                 


Glu Pro Asp Ser Trp Glu Thr Leu Asp Gln Gln Gln Phe Phe Thr Glu 
305                 310                 315                 320 


Glu Glu Leu Lys Glu Tyr Glu Asn Ile Ile Ala Leu Gln Glu Asn Glu 
                325                 330                 335     


Leu Lys Lys Lys Ala Asp Glu Leu Gln Lys Gln Lys Glu Glu Leu Gln 
            340                 345                 350         


Arg Gln His Asp Gln Leu Glu Ala Gln Lys Leu Glu Tyr His Gln Val 
        355                 360                 365             


Ile Gln Gln Met Glu Gln Lys Lys Leu Gln Gln Gly Ile Pro Pro Ser 
    370                 375                 380                 


Gly Pro Ala Gly Glu Leu Lys Phe Glu Pro His Ile 
385                 390                 395     


<210>  1614
<211>  400
<212>  PRT
<213>  Homo Sapiens

<400>  1614

Met Met Asp Leu Arg Asn Thr Pro Ala Lys Ser Leu Asp Lys Phe Ile 
1               5                   10                  15      


Glu Asp Tyr Leu Leu Pro Asp Thr Cys Phe Arg Met Gln Ile Asn His 
            20                  25                  30          


Ala Ile Asp Ile Ile Cys Gly Phe Leu Lys Glu Arg Cys Phe Arg Gly 
        35                  40                  45              


Ser Ser Tyr Pro Val Cys Val Ser Lys Val Val Lys Gly Gly Ser Ser 
    50                  55                  60                  


Gly Lys Gly Thr Thr Leu Arg Gly Arg Ser Asp Ala Asp Leu Val Val 
65                  70                  75                  80  


Phe Leu Ser Pro Leu Thr Thr Phe Gln Asp Gln Leu Asn Arg Arg Gly 
                85                  90                  95      


Glu Phe Ile Gln Glu Ile Arg Arg Gln Leu Glu Ala Cys Gln Arg Glu 
            100                 105                 110         


Arg Ala Phe Ser Val Lys Phe Glu Val Gln Ala Pro Arg Trp Gly Asn 
        115                 120                 125             


Pro Arg Ala Leu Ser Phe Val Leu Ser Ser Leu Gln Leu Gly Glu Gly 
    130                 135                 140                 


Val Glu Phe Asp Val Leu Pro Ala Phe Asp Ala Leu Gly Gln Leu Thr 
145                 150                 155                 160 


Gly Gly Tyr Lys Pro Asn Pro Gln Ile Tyr Val Lys Leu Ile Glu Glu 
                165                 170                 175     


Cys Thr Asp Leu Gln Lys Glu Gly Glu Phe Ser Thr Cys Phe Thr Glu 
            180                 185                 190         


Leu Gln Arg Asp Phe Leu Lys Gln Arg Pro Thr Lys Leu Lys Ser Leu 
        195                 200                 205             


Ile Arg Leu Val Lys His Trp Tyr Gln Asn Cys Lys Lys Lys Leu Gly 
    210                 215                 220                 


Lys Leu Pro Pro Gln Tyr Ala Leu Glu Leu Leu Thr Val Tyr Ala Trp 
225                 230                 235                 240 


Glu Arg Gly Ser Met Lys Thr His Phe Asn Thr Ala Gln Gly Phe Arg 
                245                 250                 255     


Thr Val Leu Glu Leu Val Ile Asn Tyr Gln Gln Leu Cys Ile Tyr Trp 
            260                 265                 270         


Thr Lys Tyr Tyr Asp Phe Lys Asn Pro Ile Ile Glu Lys Tyr Leu Arg 
        275                 280                 285             


Arg Gln Leu Thr Lys Pro Arg Pro Val Ile Leu Asp Pro Ala Asp Pro 
    290                 295                 300                 


Thr Gly Asn Leu Gly Gly Gly Asp Pro Lys Gly Trp Arg Gln Leu Ala 
305                 310                 315                 320 


Gln Glu Ala Glu Ala Trp Leu Asn Tyr Pro Cys Phe Lys Asn Trp Asp 
                325                 330                 335     


Gly Ser Pro Val Ser Ser Trp Ile Leu Leu Ala Glu Ser Asn Ser Ala 
            340                 345                 350         


Asp Asp Glu Thr Asp Asp Pro Arg Arg Tyr Gln Lys Tyr Gly Tyr Ile 
        355                 360                 365             


Gly Thr His Glu Tyr Pro His Phe Ser His Arg Pro Ser Thr Leu Gln 
    370                 375                 380                 


Ala Ala Ser Thr Pro Gln Ala Glu Glu Asp Trp Thr Cys Thr Ile Leu 
385                 390                 395                 400 


<210>  1615
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  1615

Leu Ser Phe Thr Leu Glu Glu Glu Asp Ile Thr Gly Thr Trp Tyr Val 
1               5                   10                  15      


Lys Ala Met Val Val Asp Lys Asp Phe Pro Glu Asp Arg Arg Pro Arg 
            20                  25                  30          


Lys Val Ser Pro Val Lys Val Thr Ala Leu Gly Gly Gly Asn Leu Glu 
        35                  40                  45              


Ala Thr Phe Thr Phe Met Arg Glu Asp Arg Cys Ile Gln Lys Lys Ile 
    50                  55                  60                  


Leu Met Arg Lys Thr Glu Glu Pro Gly Lys Phe Ser Ala Tyr Gly Gly 
65                  70                  75                  80  


Arg Lys Leu Ile Tyr Leu Gln Glu Leu Pro Gly Thr Asp Asp Tyr Val 
                85                  90                  95      


Phe Tyr Cys Lys Asp Gln Arg Arg Gly Gly Leu Arg Tyr Met Gly Lys 
            100                 105                 110         


Leu Val Gly Arg Asn Pro Asn Thr Asn Leu Glu Ala Leu Glu Glu Phe 
        115                 120                 125             


Lys Lys Leu Val Gln His Lys Gly Leu Ser Glu Glu Asp Ile Phe Met 
    130                 135                 140                 


Pro Leu Gln Thr Gly Ser Cys Val Leu Glu His 
145                 150                 155 


<210>  1616
<211>  460
<212>  PRT
<213>  Homo Sapiens

<400>  1616

His Pro Leu Asp Thr Pro His Leu Pro Gln Glu Leu Pro Pro Gly Leu 
1               5                   10                  15      


Pro Asn Asn Ile Asn Ile Thr Phe Phe Ser Gly Met Phe Lys Asn Val 
            20                  25                  30          


Glu Ser Val Ala Glu Ile Phe Asp Cys Leu Gly Pro His Phe Thr Trp 
        35                  40                  45              


Leu Gln Ala Val Phe Thr Asn Phe Pro Val Leu Ile Gln Phe Val Asn 
    50                  55                  60                  


Gly Met Lys Cys Val Ala Gly Leu Cys Pro Arg Asp Phe Glu Asp Tyr 
65                  70                  75                  80  


Gly Cys Thr Cys Arg Phe Glu Met Glu Gly Leu Pro Val Asp Glu Ser 
                85                  90                  95      


Asp Ser Cys Cys Phe Gln His Arg Arg Cys Tyr Glu Glu Ala Ala Glu 
            100                 105                 110         


Met Asp Cys Leu Gln Asp Pro Ala Lys Leu Ser Thr Glu Val Asn Cys 
        115                 120                 125             


Val Ser Lys Lys Ile Ile Cys Glu Ser Lys Asp Asn Cys Glu His Leu 
    130                 135                 140                 


Leu Cys Thr Cys Asp Lys Ala Ala Ile Glu Cys Leu Ala Arg Ser Ser 
145                 150                 155                 160 


Leu Asn Ser Ser Leu Asn Leu Leu Asp Thr Ser Phe Cys Leu Ala Gln 
                165                 170                 175     


Thr Pro Glu Thr Thr Ile Lys Glu Asp Leu Thr Thr Leu Leu Pro Arg 
            180                 185                 190         


Val Val Pro Val Glu Pro Thr Asp Thr Ser Leu Thr Ala Leu Ser Gly 
        195                 200                 205             


Glu Glu Ala Gly His Asp Gln Glu Gly Val Gly Ala Ala Arg Ala Thr 
    210                 215                 220                 


Ser Pro Pro Gly Ser Ala Glu Ile Val Ala Thr Arg Val Thr Ala Lys 
225                 230                 235                 240 


Ile Val Thr Leu Val Pro Ala Gly Ile Lys Ser Leu Gly Leu Ala Val 
                245                 250                 255     


Ser Ser Val Glu Asn Asp Pro Glu Glu Thr Thr Glu Lys Ala Cys Asp 
            260                 265                 270         


Arg Phe Thr Phe Leu His Leu Gly Ser Gly Asp Asn Met Gln Val Met 
        275                 280                 285             


Pro Gln Leu Gly Glu Met Leu Phe Cys Leu Thr Ser Arg Cys Pro Glu 
    290                 295                 300                 


Glu Phe Glu Ser Tyr Gly Cys Tyr Cys Gly Gln Glu Gly Arg Gly Glu 
305                 310                 315                 320 


Pro Arg Asp Asp Leu Asp Arg Cys Cys Leu Ser His His Cys Cys Leu 
                325                 330                 335     


Glu Gln Val Arg Arg Leu Gly Cys Leu Leu Glu Arg Leu Pro Trp Ser 
            340                 345                 350         


Pro Val Val Cys Val Asp His Thr Pro Lys Cys Gly Gly Gln Ser Leu 
        355                 360                 365             


Cys Glu Lys Leu Leu Cys Ala Cys Asp Gln Thr Ala Ala Glu Cys Met 
    370                 375                 380                 


Thr Ser Ala Ser Phe Asn Gln Ser Leu Lys Ser Pro Ser Arg Leu Gly 
385                 390                 395                 400 


Cys Pro Gly Gln Pro Ala Ala Cys Glu Asp Ser Leu His Pro Val Pro 
                405                 410                 415     


Ala Ala Pro Thr Leu Gly Ser Ser Ser Glu Glu Asp Ser Glu Glu Asp 
            420                 425                 430         


Pro Pro Gln Glu Asp Leu Gly Arg Ala Lys Arg Phe Leu Arg Lys Ser 
        435                 440                 445             


Leu Gly Pro Leu Gly Ile Gly Pro Leu His Gly Arg 
    450                 455                 460 


<210>  1617
<211>  264
<212>  PRT
<213>  Homo Sapiens

<400>  1617

Ala Pro Leu Ile Pro Gln Arg Leu Met Ser Ala Ser Asn Ser Asn Glu 
1               5                   10                  15      


Leu Leu Leu Asn Leu Asn Asn Gly Gln Leu Leu Pro Leu Gln Leu Gln 
            20                  25                  30          


Gly Pro Leu Asn Ser Trp Ile Pro Pro Phe Ser Gly Ile Leu Gln Gln 
        35                  40                  45              


Gln Gln Gln Ala Gln Ile Pro Gly Leu Ser Gln Phe Ser Leu Ser Ala 
    50                  55                  60                  


Leu Asp Gln Phe Ala Gly Leu Leu Pro Asn Gln Ile Pro Leu Thr Gly 
65                  70                  75                  80  


Glu Ala Ser Phe Ala Gln Gly Ala Gln Ala Gly Gln Val Asp Pro Leu 
                85                  90                  95      


Gln Leu Gln Thr Pro Pro Gln Thr Gln Pro Gly Pro Ser His Val Met 
            100                 105                 110         


Pro Tyr Val Phe Ser Phe Lys Met Pro Gln Glu Gln Gly Gln Met Phe 
        115                 120                 125             


Gln Tyr Tyr Pro Val Tyr Met Val Leu Pro Trp Glu Gln Pro Gln Gln 
    130                 135                 140                 


Thr Val Pro Arg Ser Pro Gln Gln Thr Arg Gln Gln Gln Tyr Glu Glu 
145                 150                 155                 160 


Gln Ile Pro Phe Tyr Ala Gln Phe Gly Tyr Ile Pro Gln Leu Ala Glu 
                165                 170                 175     


Pro Ala Ile Ser Gly Gly Gln Gln Gln Leu Ala Phe Asp Pro Gln Leu 
            180                 185                 190         


Gly Thr Ala Pro Glu Ile Ala Val Met Ser Thr Gly Glu Glu Ile Pro 
        195                 200                 205             


Tyr Leu Gln Lys Glu Ala Ile Asn Phe Arg His Asp Ser Ala Gly Val 
    210                 215                 220                 


Phe Met Pro Ser Thr Ser Pro Lys Pro Ser Thr Thr Asn Val Phe Thr 
225                 230                 235                 240 


Ser Ala Val Asp Gln Thr Ile Thr Pro Glu Leu Pro Glu Glu Lys Asp 
                245                 250                 255     


Lys Thr Asp Ser Leu Arg Glu Pro 
            260                 


<210>  1618
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  1618

Gln Glu Glu Val Phe Thr Pro Pro Gly Asp Ser Gln Asn Asn Ala Asp 
1               5                   10                  15      


Ala Thr Asp Cys Gln Ile Phe Thr Leu Thr Pro Pro Pro Ala Pro Arg 
            20                  25                  30          


Ser Pro Val Thr Arg Ala Gln Pro Ile Thr Lys Thr Pro Arg Cys Pro 
        35                  40                  45              


Phe His Phe Phe Pro Arg Arg Pro Arg Ile His Phe Arg Phe Pro Asn 
    50                  55                  60                  


Arg Pro Phe Val Pro Ser Arg Cys Asn His Arg Phe Pro Phe Gln Pro 
65                  70                  75                  80  


Phe Tyr Trp Pro His Arg Tyr Leu Thr Tyr Arg Tyr Phe Pro Arg Arg 
                85                  90                  95      


Arg Leu Gln Arg Gly Ser Ser Ser Glu Glu Ser 
            100                 105         


<210>  1619
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1619

Ile Gln Val His Cys Thr Gln Phe Trp Phe Phe Ala Arg Ile Lys Pro 
1               5                   10                  15      


Thr Ile Phe Tyr Asn Leu Tyr Val Asn Pro Asp Glu Val Phe Leu Gly 
            20                  25                  30          


Asp Gly Cys His Val Thr His Val Leu Pro Asn Val Tyr Tyr Glu Phe 
        35                  40                  45              


Phe Tyr His Pro His Asp Cys Gly Ile Val Thr Gln Pro Leu Gln Glu 
    50                  55                  60                  


Val Leu Leu Leu Lys Thr Lys Ile Arg Tyr Ile Ser Arg Asp Ser Thr 
65                  70                  75                  80  


Val Arg Ser Glu Met Pro Leu Ser Cys Val Val His Lys Gln Lys Cys 
                85                  90                  95      


Gln 
    


<210>  1620
<211>  141
<212>  PRT
<213>  Homo Sapiens

<400>  1620

Glu Asn Leu His Val Lys Ile Ser Cys Ser Leu Asp Trp Leu Met Val 
1               5                   10                  15      


Ser Val Ile Pro Val Ala Glu Ser Arg Asn Leu Tyr Ile Phe Ala Asp 
            20                  25                  30          


Glu Leu His Leu Gly Met Gly Cys Pro Ala Asn Arg Ile His Thr Tyr 
        35                  40                  45              


Val Tyr Glu Phe Ile Tyr Leu Val Arg Asp Cys Gly Ile Arg Thr Arg 
    50                  55                  60                  


Val Val Ser Glu Glu Thr Leu Leu Phe Gln Thr Glu Leu Tyr Phe Thr 
65                  70                  75                  80  


Pro Arg Asn Ile Asp His Asp Pro Gln Glu Ile His Leu Glu Cys Ser 
                85                  90                  95      


Thr Ser Arg Lys Ser Val Trp Leu Thr Pro Val Ser Thr Glu Asn Glu 
            100                 105                 110         


Ile Lys Leu Asp Pro Ser Pro Phe Ile Ala Asp Phe Gln Thr Thr Ala 
        115                 120                 125             


Glu Glu Leu Gly Leu Leu Ser Ser Ser Pro Asn Leu Leu 
    130                 135                 140     


<210>  1621
<211>  454
<212>  PRT
<213>  Homo Sapiens

<400>  1621

Lys Thr Thr Pro His Thr Lys Phe Thr Lys Lys Ser Glu Glu Arg Glu 
1               5                   10                  15      


Met Pro Lys Gly Leu Lys Pro Ser Ser Gly Pro Pro Pro Glu Glu Glu 
            20                  25                  30          


Glu Thr Leu Phe Thr Glu Met Ala Glu Met Ala Glu Pro Ile Thr Lys 
        35                  40                  45              


Pro Ser Ala Leu Asp Ser Val Phe Gly Thr Ala Thr Leu Ser Pro Phe 
    50                  55                  60                  


Glu Asn Phe Thr Leu Asp Pro Ala Asp Phe Phe Leu Asn Cys Cys Asp 
65                  70                  75                  80  


Cys Cys Ser Pro Val Pro Gly Gln Lys Gly Glu Pro Gly Glu Thr Gly 
                85                  90                  95      


Gln Pro Gly Pro Lys Gly Glu Ala Gly Asn Leu Gly Ile Pro Gly Pro 
            100                 105                 110         


Pro Gly Val Val Gly Pro Gln Gly Pro Arg Gly Tyr Lys Gly Glu Lys 
        115                 120                 125             


Gly Leu Lys Gly Glu Arg Gly Asp Gln Gly Val Pro Gly Tyr Pro Gly 
    130                 135                 140                 


Lys Pro Gly Ala Gln Gly Glu Pro Gly Pro Lys Gly Asp Lys Gly Asn 
145                 150                 155                 160 


Ile Gly Leu Gly Gly Val Lys Gly Gln Lys Gly Ser Lys Gly Asp Thr 
                165                 170                 175     


Cys Gly Asn Cys Thr Lys Gly Glu Lys Gly Asp Gln Gly Ala Met Gly 
            180                 185                 190         


Ser Pro Gly Leu His Gly Gly Pro Gly Ala Lys Gly Glu Lys Gly Glu 
        195                 200                 205             


Met Gly Glu Lys Gly Glu Met Gly Asp Lys Gly Cys Cys Gly Asp Ser 
    210                 215                 220                 


Gly Glu Arg Gly Gly Lys Gly Gln Lys Gly Glu Gly Gly Met Lys Gly 
225                 230                 235                 240 


Glu Lys Gly Ser Lys Gly Asp Ser Gly Met Glu Gly Lys Ser Gly Arg 
                245                 250                 255     


Asn Gly Leu Pro Gly Ala Lys Gly Asp Pro Gly Ile Lys Gly Glu Lys 
            260                 265                 270         


Gly Glu Leu Gly Pro Pro Gly Leu Leu Gly Pro Thr Gly Pro Lys Gly 
        275                 280                 285             


Asp Ile Gly Asn Lys Gly Val Arg Gly Pro Thr Gly Lys Lys Gly Ser 
    290                 295                 300                 


Arg Gly Phe Lys Gly Ser Lys Gly Glu Leu Ala Arg Val Pro Arg Ser 
305                 310                 315                 320 


Ala Phe Ser Ala Gly Leu Ser Lys Pro Phe Pro Pro Pro Asn Ile Pro 
                325                 330                 335     


Ile Lys Phe Glu Lys Ile Leu Tyr Asn Asp Gln Gly Asn Tyr Ser Pro 
            340                 345                 350         


Val Thr Gly Lys Phe Asn Cys Ser Ile Pro Gly Thr Tyr Val Phe Ser 
        355                 360                 365             


Tyr His Ile Thr Val Arg Gly Arg Pro Ala Arg Ile Ser Leu Val Ala 
    370                 375                 380                 


Gln Asn Lys Lys Gln Phe Lys Ser Arg Glu Thr Leu Tyr Gly Gln Glu 
385                 390                 395                 400 


Ile Asp Gln Ala Ser Leu Leu Val Ile Leu Lys Leu Ser Ala Gly Asp 
                405                 410                 415     


Gln Val Trp Leu Glu Val Ser Lys Asp Trp Asn Gly Val Tyr Val Ser 
            420                 425                 430         


Ala Glu Asp Asp Ser Ile Phe Thr Gly Phe Leu Leu Tyr Pro Glu Glu 
        435                 440                 445             


Thr Ser Gly Ile Ser Pro 
    450                 


<210>  1622
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  1622

Lys Pro Val Gln Glu Glu Gly Asp Pro Tyr Ala Glu Leu Pro Ala Met 
1               5                   10                  15      


Pro Tyr Trp Pro Phe Ser Thr Ser Asp Phe Trp Asn Tyr Val Gln His 
            20                  25                  30          


Phe Gln Ala Leu Gly Ala Tyr Pro Gln Ile Glu Asp Met Ala Arg Thr 
        35                  40                  45              


Phe Phe Ala His Phe Pro Leu Gly Ser Thr Leu Gly Phe His Val Pro 
    50                  55                  60                  


Tyr Gln Glu Asp 
65              


<210>  1623
<211>  513
<212>  PRT
<213>  Homo Sapiens

<400>  1623

Ile Leu Gly Gly Ser Gln Val Glu Lys Gly Ser Tyr Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Lys Gln Arg Gln Lys His Ile Cys Gly Gly Ser Ile Val Ser 
            20                  25                  30          


Pro Gln Trp Val Ile Thr Ala Ala His Cys Ile Ala Asn Arg Asn Ile 
        35                  40                  45              


Val Ser Thr Leu Asn Val Thr Ala Gly Glu Tyr Asp Leu Ser Gln Thr 
    50                  55                  60                  


Asp Pro Gly Glu Gln Thr Leu Thr Ile Glu Thr Val Ile Ile His Pro 
65                  70                  75                  80  


His Phe Ser Thr Lys Lys Pro Met Asp Tyr Asp Ile Ala Leu Leu Lys 
                85                  90                  95      


Met Ala Gly Ala Phe Gln Phe Gly His Phe Val Gly Pro Ile Cys Leu 
            100                 105                 110         


Pro Glu Leu Arg Glu Gln Phe Glu Ala Gly Phe Ile Cys Thr Thr Ala 
        115                 120                 125             


Gly Trp Gly Arg Leu Thr Glu Gly Gly Val Leu Ser Gln Val Leu Gln 
    130                 135                 140                 


Glu Val Asn Leu Pro Ile Leu Thr Trp Glu Glu Cys Val Ala Ala Leu 
145                 150                 155                 160 


Leu Thr Leu Lys Arg Pro Ile Ser Gly Lys Thr Phe Leu Cys Thr Gly 
                165                 170                 175     


Phe Pro Asp Gly Gly Arg Asp Ala Cys Gln Gly Asp Ser Gly Gly Ser 
            180                 185                 190         


Leu Met Cys Arg Asn Lys Lys Gly Ala Trp Thr Leu Ala Gly Val Thr 
        195                 200                 205             


Ser Trp Gly Leu Gly Cys Gly Arg Gly Trp Arg Asn Asn Val Arg Lys 
    210                 215                 220                 


Ser Asp Gln Gly Ser Pro Gly Ile Phe Thr Asp Ile Ser Lys Val Leu 
225                 230                 235                 240 


Pro Trp Ile His Glu His Ile Gln Thr Gly Asn Arg Arg Lys Ser Ser 
                245                 250                 255     


Arg Ala Trp Cys Ser Glu Gln Asp Val Ile Val Ser Gly Ala Glu Gly 
            260                 265                 270         


Lys Leu His Phe Pro Glu Ser Leu His Leu Tyr Tyr Glu Ser Lys Gln 
        275                 280                 285             


Arg Cys Val Trp Thr Leu Leu Val Pro Glu Glu Met His Val Leu Leu 
    290                 295                 300                 


Ser Phe Ser His Leu Asp Val Glu Ser Cys His His Ser Tyr Leu Ser 
305                 310                 315                 320 


Met Tyr Ser Leu Glu Asp Arg Pro Ile Gly Lys Phe Cys Gly Glu Ser 
                325                 330                 335     


Leu Pro Ser Ser Ile Leu Ile Gly Ser Asn Ser Leu Arg Leu Lys Phe 
            340                 345                 350         


Val Ser Asp Ala Thr Asp Asn Ala Ala Arg Phe Asn Leu Thr Tyr Lys 
        355                 360                 365             


Ala Leu Lys Pro Asn Tyr Ile Pro Asp Ser Gly Cys Ser Tyr Leu Thr 
    370                 375                 380                 


Val Leu Phe Glu Glu Gly Leu Ile Gln Ser Leu Asn Tyr Pro Glu Asn 
385                 390                 395                 400 


Tyr Ser Asp Lys Ala Asn Cys Asp Trp Ile Phe Gln Ala Ser Lys His 
                405                 410                 415     


His Leu Ile Lys Leu Ser Phe Gln Ser Leu Glu Ile Glu Glu Ser Gly 
            420                 425                 430         


Asp Cys Thr Ser Asp Tyr Val Thr Val His Ser Asp Val Glu Arg Lys 
        435                 440                 445             


Lys Glu Ile Ala Arg Leu Cys Gly Tyr Asp Val Pro Thr Pro Val Leu 
    450                 455                 460                 


Ser Pro Ser Ser Ile Met Leu Ile Ser Phe His Ser Asp Glu Asn Gly 
465                 470                 475                 480 


Thr Cys Arg Gly Phe Gln Ala Thr Val Ser Phe Ile Pro Lys Ala Gly 
                485                 490                 495     


Lys Lys Ile Glu Leu Pro Thr Leu Trp Phe Pro Val Leu Ile Leu Val 
            500                 505                 510         


Met 
    


<210>  1624
<211>  274
<212>  PRT
<213>  Homo Sapiens

<400>  1624

Gln Lys Ser Tyr Gln Glu Ser Glu Thr Gly Pro Glu Ser Ser Ile Ile 
1               5                   10                  15      


Thr Lys Val Lys Gly Ile Thr Thr Ser Glu His Lys Val Trp Asp Val 
            20                  25                  30          


Glu Glu Tyr Val Lys Pro Pro Glu Gly Gly Ser Val Phe Ser Ile Ile 
        35                  40                  45              


Thr Arg Val Glu Ala Thr His Ser Gln Thr Gln Gly Thr Cys Pro Glu 
    50                  55                  60                  


Ser Ile Arg Val His Asn Ala Thr Cys Leu Ser Asp Ala Asp Cys Val 
65                  70                  75                  80  


Ala Gly Glu Leu Asp Met Leu Gly Asn Gly Leu Arg Thr Gly Arg Cys 
                85                  90                  95      


Val Pro Tyr Tyr Gln Gly Pro Ser Lys Thr Cys Glu Val Phe Gly Trp 
            100                 105                 110         


Cys Pro Val Glu Asp Gly Ala Ser Val Ser Gln Phe Leu Gly Thr Met 
        115                 120                 125             


Ala Pro Asn Phe Thr Ile Leu Ile Lys Asn Ser Ile His Tyr Pro Lys 
    130                 135                 140                 


Phe His Phe Ser Lys Gly Asn Ile Ala Asp Arg Thr Asp Gly Tyr Leu 
145                 150                 155                 160 


Lys Arg Cys Thr Phe His Glu Ala Ser Asp Leu Tyr Cys Pro Ile Phe 
                165                 170                 175     


Lys Leu Gly Phe Ile Val Glu Lys Ala Gly Glu Ser Phe Thr Glu Leu 
            180                 185                 190         


Ala His Lys Gly Gly Val Ile Gly Val Ile Ile Asn Trp Asp Cys Asp 
        195                 200                 205             


Leu Asp Leu Pro Ala Ser Glu Cys Asn Pro Lys Tyr Ser Phe Arg Arg 
    210                 215                 220                 


Leu Asp Pro Lys His Val Pro Ala Ser Ser Gly Tyr Asn Phe Arg Phe 
225                 230                 235                 240 


Ala Lys Tyr Tyr Lys Ile Asn Gly Thr Thr Thr Arg Thr Leu Ile Lys 
                245                 250                 255     


Ala Tyr Gly Ile Arg Ile Asp Val Ile Val His Gly Gln Ala Gly Lys 
            260                 265                 270         


Phe Ser 
        


<210>  1625
<211>  472
<212>  PRT
<213>  Homo Sapiens

<400>  1625

Asp Ala Pro Pro Gly Lys Ile Ala Val Val Gly Ala Gly Ile Gly Gly 
1               5                   10                  15      


Ser Ala Val Ala His Phe Leu Gln Gln His Phe Gly Pro Arg Val Gln 
            20                  25                  30          


Ile Asp Val Tyr Glu Lys Gly Thr Val Gly Gly Arg Leu Ala Thr Ile 
        35                  40                  45              


Ser Val Asn Lys Gln His Tyr Glu Ser Gly Ala Ala Ser Phe His Ser 
    50                  55                  60                  


Leu Ser Leu His Met Gln Asp Phe Val Lys Leu Leu Gly Leu Arg His 
65                  70                  75                  80  


Arg Arg Glu Val Val Gly Arg Ser Ala Ile Phe Gly Gly Glu His Phe 
                85                  90                  95      


Met Leu Glu Glu Thr Asp Trp Tyr Leu Leu Asn Leu Phe Arg Leu Trp 
            100                 105                 110         


Trp His Tyr Gly Ile Ser Phe Leu Arg Leu Gln Met Trp Val Glu Glu 
        115                 120                 125             


Val Met Glu Lys Phe Met Arg Ile Tyr Lys Tyr Gln Ala His Gly Tyr 
    130                 135                 140                 


Ala Phe Ser Gly Val Glu Glu Leu Leu Tyr Ser Leu Gly Glu Ser Thr 
145                 150                 155                 160 


Phe Val Asn Met Thr Gln His Ser Val Ala Glu Ser Leu Leu Gln Val 
                165                 170                 175     


Gly Val Thr Gln Arg Phe Ile Asp Asp Val Val Ser Ala Val Leu Arg 
            180                 185                 190         


Ala Ser Tyr Gly Gln Ser Ala Ala Met Pro Ala Phe Ala Gly Ala Met 
        195                 200                 205             


Ser Leu Ala Gly Ala Gln Gly Ser Leu Trp Ser Val Glu Gly Gly Asn 
    210                 215                 220                 


Lys Leu Val Cys Ser Gly Leu Leu Lys Leu Thr Lys Ala Asn Val Ile 
225                 230                 235                 240 


His Ala Thr Val Thr Ser Val Thr Leu His Ser Thr Glu Gly Lys Ala 
                245                 250                 255     


Leu Tyr Gln Val Ala Tyr Glu Asn Glu Val Gly Asn Ser Ser Asp Phe 
            260                 265                 270         


Tyr Asp Ile Val Val Ile Ala Thr Pro Leu His Leu Asp Asn Ser Ser 
        275                 280                 285             


Ser Asn Leu Thr Phe Ala Gly Phe His Pro Pro Ile Asp Asp Val Gln 
    290                 295                 300                 


Gly Ser Phe Gln Pro Thr Val Val Ser Leu Val His Gly Tyr Leu Asn 
305                 310                 315                 320 


Ser Ser Tyr Phe Gly Phe Pro Asp Pro Lys Leu Phe Pro Phe Ala Asn 
                325                 330                 335     


Ile Leu Thr Thr Asp Phe Pro Ser Phe Phe Cys Thr Leu Asp Asn Ile 
            340                 345                 350         


Cys Pro Val Asn Ile Ser Ala Ser Phe Arg Arg Lys Gln Pro Gln Glu 
        355                 360                 365             


Ala Ala Val Trp Arg Val Gln Ser Pro Lys Pro Leu Phe Arg Thr Gln 
    370                 375                 380                 


Leu Lys Thr Leu Phe Arg Ser Tyr Tyr Ser Val Gln Thr Ala Glu Trp 
385                 390                 395                 400 


Gln Ala His Pro Leu Tyr Gly Ser Arg Pro Thr Leu Pro Arg Phe Ala 
                405                 410                 415     


Leu His Asp Gln Leu Phe Tyr Leu Asn Ala Leu Glu Trp Ala Ala Ser 
            420                 425                 430         


Ser Val Glu Val Met Ala Val Ala Ala Lys Asn Val Ala Leu Leu Ala 
        435                 440                 445             


Tyr Asn Arg Trp Tyr Gln Asp Leu Asp Lys Ile Asp Gln Lys Asp Leu 
    450                 455                 460                 


Met His Lys Val Lys Thr Glu Leu 
465                 470         


<210>  1626
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  1626

Leu Tyr Ser Ser Ser Asp Asp Val Ile Glu Leu Thr Pro Ser Asn Phe 
1               5                   10                  15      


Asn Arg Glu Val Ile Gln Ser Asp Ser Leu Trp Leu Val Glu Phe Tyr 
            20                  25                  30          


Ala Pro Trp Cys Gly His Cys Gln Arg Leu Thr Pro Glu Trp Lys Lys 
        35                  40                  45              


Ala Ala Thr Ala Leu Lys Asp Val Val Lys Val Gly Ala Val Asp Ala 
    50                  55                  60                  


Asp Lys His His Ser Leu Gly Gly Gln Tyr Gly Val Gln Gly Phe Pro 
65                  70                  75                  80  


Thr Ile Lys Ile Phe Gly Ser Asn Lys Asn Arg Pro Glu Asp Tyr Gln 
                85                  90                  95      


Gly Gly Arg Thr Gly Glu Ala Ile Val Asp Ala Ala Leu Ser Ala Leu 
            100                 105                 110         


Arg Gln Leu Val Lys Asp Arg Leu Gly Gly Arg Ser Gly Gly Tyr Ser 
        115                 120                 125             


Ser Gly Lys Gln Gly Arg Ser Asp Ser Ser Ser Lys Lys Asp Val Ile 
    130                 135                 140                 


Glu Leu Thr Asp Asp Ser Phe Asp Lys Asn Val Leu Asp Ser Glu Asp 
145                 150                 155                 160 


Val Trp Met Val Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Asn 
                165                 170                 175     


Leu Glu Pro Glu Trp Ala Ala Ala Ala Ser Glu Val Lys Glu Gln Thr 
            180                 185                 190         


Lys Gly Lys Val Lys Leu Ala Ala Val Asp Ala Thr Val Asn Gln Val 
        195                 200                 205             


Leu Ala Ser Arg Tyr Gly Ile Arg Gly Phe Pro Thr Ile Lys Ile Phe 
    210                 215                 220                 


Gln Lys Gly Glu Ser Pro Val Asp Tyr Asp Gly Gly Arg Thr Arg Ser 
225                 230                 235                 240 


Asp Ile Val Ser Arg Ala Leu Asp Leu Phe Ser Asp Asn Ala Pro Pro 
                245                 250                 255     


Pro Glu Leu Leu Glu Ile Ile Asn Glu Asp Ile Ala Lys Arg Thr Cys 
            260                 265                 270         


Glu Glu His Gln Leu Cys Val Val Ala Val Leu Pro His Ile Leu Asp 
        275                 280                 285             


Thr Gly Ala Ala Gly Arg Asn Ser Tyr Leu Glu Val Leu Leu Lys Leu 
    290                 295                 300                 


Ala Asp Lys Tyr Lys Lys Lys Met Trp Gly Trp Leu Trp Thr Glu Ala 
305                 310                 315                 320 


Gly Ala Gln Ser Glu Leu Glu Thr Ala Leu Gly Ile Gly Gly Phe Gly 
                325                 330                 335     


Tyr Pro Ala Met Ala Ala Ile Asn Ala Arg Lys Met Lys Phe Ala Leu 
            340                 345                 350         


Leu Lys Gly Ser Phe Ser Glu Gln Gly Ile Asn Glu Phe Leu Arg Glu 
        355                 360                 365             


Leu Ser Phe Gly Arg Gly Ser Thr Ala Pro Val Gly Gly Gly Ala Phe 
    370                 375                 380                 


Pro Thr Ile Val Glu Arg Glu Pro Trp Asp Gly Arg Asp Gly Glu Leu 
385                 390                 395                 400 


Pro Val Glu Asp Asp Ile Asp Leu Ser Asp Val Glu Leu Asp Asp Leu 
                405                 410                 415     


Gly Lys Asp Glu Leu 
            420     


<210>  1627
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  1627

Asp Glu Asp Glu Asn Ser Pro Cys Ala His Glu Ala Leu Leu Asp Glu 
1               5                   10                  15      


Asp Thr Leu Phe Cys Gln Gly Leu Glu Val Phe Tyr Pro Glu Leu Gly 
            20                  25                  30          


Asn Ile Gly Cys Lys Val Val Pro Asp Cys Asn Asn Tyr Arg Gln Lys 
        35                  40                  45              


Ile Thr Ser Trp Met Glu Pro Ile Val Lys Phe Pro Gly Ala Val Asp 
    50                  55                  60                  


Gly Ala Thr Tyr Ile Leu Val Met Val Asp Pro Asp Ala Pro Ser Arg 
65                  70                  75                  80  


Ala Glu Pro Arg Gln Arg Phe Trp Arg His Trp Leu Val Thr Asp Ile 
                85                  90                  95      


Lys Gly Ala Asp Leu Lys Lys Gly Lys Ile Gln Gly Gln Glu Leu Ser 
            100                 105                 110         


Ala Tyr Gln Ala Pro Ser Pro Pro Ala His Ser Gly Phe His Arg Tyr 
        115                 120                 125             


Gln Phe Phe Val Tyr Leu Gln Glu Gly Lys Val Ile Ser Leu Leu Pro 
    130                 135                 140                 


Lys Glu Asn Lys Thr Arg Gly Ser Trp Lys Met Asp Arg Phe Leu Asn 
145                 150                 155                 160 


Arg Phe His Leu Gly Glu Pro Glu Ala Ser Thr Gln Phe Met Thr Gln 
                165                 170                 175     


Asn Tyr Gln Asp Ser Pro Thr Leu Gln Ala Pro Arg Glu Arg Ala Ser 
            180                 185                 190         


Glu Pro Lys His Lys Asn Gln Ala Glu Ile Ala Ala Cys 
        195                 200                 205 


<210>  1628
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  1628

Val Asp Glu Gln Pro Leu Glu Asn Tyr Leu Asp Met Glu Tyr Phe Gly 
1               5                   10                  15      


Thr Ile Gly Ile Gly Thr Pro Ala Gln Asp Phe Thr Val Val Phe Asp 
            20                  25                  30          


Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Val Tyr Cys Ser Ser Leu 
        35                  40                  45              


Ala Cys Thr Asn His Asn Arg Phe Asn Pro Glu Asp Ser Ser Thr Tyr 
    50                  55                  60                  


Gln Ser Thr Ser Glu Thr Val Ser Ile Thr Tyr Gly Thr Gly Ser Met 
65                  70                  75                  80  


Thr Gly Ile Leu Gly Tyr Asp Thr Val Gln Val Gly Gly Ile Ser Asp 
                85                  90                  95      


Thr Asn Gln Ile Phe Gly Leu Ser Glu Thr Glu Pro Gly Ser Phe Leu 
            100                 105                 110         


Tyr Tyr Ala Pro Phe Asp Gly Ile Leu Gly Leu Ala Tyr Pro Ser Ile 
        115                 120                 125             


Ser Ser Ser Gly Ala Thr Pro Val Phe Asp Asn Ile Trp Asn Gln Gly 
    130                 135                 140                 


Leu Val Ser Gln Asp Leu Phe Ser Val Tyr Leu Ser Ala Asp Asp Gln 
145                 150                 155                 160 


Ser Gly Ser Val Val Ile Phe Gly Gly Ile Asp Ser Ser Tyr Tyr Thr 
                165                 170                 175     


Gly Ser Leu Asn Trp Val Pro Val Thr Val Glu Gly Tyr Trp Gln Ile 
            180                 185                 190         


Thr Val Asp Ser Ile Thr Met Asn Gly Glu Ala Ile Ala Cys Ala Glu 
        195                 200                 205             


Gly Cys Gln Ala Ile Val Asp Thr Gly Thr Ser Leu Leu Thr Gly Pro 
    210                 215                 220                 


Thr Ser Pro Ile Ala Asn Ile Gln Ser Asp Ile Gly Ala Ser Glu Asn 
225                 230                 235                 240 


Ser Asp Gly Asp Met Val Val Ser Cys Ser Ala Ile Ser Ser Leu Pro 
                245                 250                 255     


Asp Ile Val Phe Thr Ile Asn Gly Val Gln Tyr Pro Val Pro Pro Ser 
            260                 265                 270         


Ala Tyr Ile Leu Gln Ser Glu Gly Ser Cys Ile Ser Gly Phe Gln Gly 
        275                 280                 285             


Met Asn Leu Pro Thr Glu Ser Gly Glu Leu Trp Ile Leu Gly Asp Val 
    290                 295                 300                 


Phe Ile Arg Gln Tyr Phe Thr Val Phe Asp Arg Ala Asn Asn Gln Val 
305                 310                 315                 320 


Gly Leu Ala Pro Val Ala 
                325     


<210>  1629
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  1629

Ser Val Thr Tyr Glu Pro Met Ala Tyr Met Asp Ala Ala Tyr Phe Gly 
1               5                   10                  15      


Glu Ile Ser Ile Gly Thr Pro Pro Gln Asn Phe Leu Val Leu Phe Asp 
            20                  25                  30          


Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Val Tyr Cys Gln Ser Gln 
        35                  40                  45              


Ala Cys Thr Ser His Ser Arg Phe Asn Pro Ser Glu Ser Ser Thr Tyr 
    50                  55                  60                  


Ser Thr Asn Gly Gln Thr Phe Ser Leu Gln Tyr Gly Ser Gly Ser Leu 
65                  70                  75                  80  


Thr Gly Phe Phe Gly Tyr Asp Thr Leu Thr Val Gln Ser Ile Gln Val 
                85                  90                  95      


Pro Asn Gln Glu Phe Gly Leu Ser Glu Asn Glu Pro Gly Thr Asn Phe 
            100                 105                 110         


Val Tyr Ala Gln Phe Asp Gly Ile Met Gly Leu Ala Tyr Pro Ala Leu 
        115                 120                 125             


Ser Val Asp Glu Ala Thr Thr Ala Met Gln Gly Met Val Gln Glu Gly 
    130                 135                 140                 


Ala Leu Thr Ser Pro Val Phe Ser Val Tyr Leu Ser Asn Gln Gln Gly 
145                 150                 155                 160 


Ser Ser Gly Gly Ala Val Val Phe Gly Gly Val Asp Ser Ser Leu Tyr 
                165                 170                 175     


Thr Gly Gln Ile Tyr Trp Ala Pro Val Thr Gln Glu Leu Tyr Trp Gln 
            180                 185                 190         


Ile Gly Ile Glu Glu Phe Leu Ile Gly Gly Gln Ala Ser Gly Trp Cys 
        195                 200                 205             


Ser Glu Gly Cys Gln Ala Ile Val Asp Thr Gly Thr Ser Leu Leu Thr 
    210                 215                 220                 


Val Pro Gln Gln Tyr Met Ser Ala Leu Leu Gln Ala Thr Gly Ala Gln 
225                 230                 235                 240 


Glu Asp Glu Tyr Gly Gln Phe Leu Val Asn Cys Asn Ser Ile Gln Asn 
                245                 250                 255     


Leu Pro Ser Leu Thr Phe Ile Ile Asn Gly Val Glu Phe Pro Leu Pro 
            260                 265                 270         


Pro Ser Ser Tyr Ile Leu Ser Asn Asn Gly Tyr Cys Thr Val Gly Val 
        275                 280                 285             


Glu Pro Thr Tyr Leu Ser Ser Gln Asn Gly Gln Pro Leu Trp Ile Leu 
    290                 295                 300                 


Gly Asp Val Phe Leu Arg Ser Tyr Tyr Ser Val Tyr Asp Leu Gly Asn 
305                 310                 315                 320 


Asn Arg Val Gly Phe Ala Thr Ala Ala 
                325                 


<210>  1630
<211>  555
<212>  PRT
<213>  Homo Sapiens

<400>  1630

Ser Leu Pro Leu Leu Met Asp Ser Val Ile Gln Ala Leu Ala Glu Leu 
1               5                   10                  15      


Glu Gln Lys Val Pro Ala Ala Lys Thr Arg His Thr Ala Ser Ala Trp 
            20                  25                  30          


Leu Met Ser Ala Pro Asn Ser Gly Pro His Asn Arg Leu Tyr His Phe 
        35                  40                  45              


Leu Leu Gly Ala Trp Ser Leu Asn Ala Thr Glu Leu Asp Pro Cys Pro 
    50                  55                  60                  


Leu Ser Pro Glu Leu Leu Gly Leu Thr Lys Glu Val Ala Arg His Asp 
65                  70                  75                  80  


Val Arg Glu Gly Lys Glu Tyr Gly Val Val Leu Ala Pro Asp Gly Ser 
                85                  90                  95      


Thr Val Ala Val Glu Pro Leu Leu Ala Gly Leu Glu Ala Gly Leu Gln 
            100                 105                 110         


Gly Arg Arg Val Ile Asn Leu Pro Leu Asp Ser Met Ala Ala Pro Trp 
        115                 120                 125             


Glu Thr Gly Asp Thr Phe Pro Asp Val Val Ala Ile Ala Pro Asp Val 
    130                 135                 140                 


Arg Ala Thr Ser Ser Pro Gly Leu Arg Asp Gly Ser Pro Asp Val Thr 
145                 150                 155                 160 


Thr Ala Asp Ile Gly Ala Asn Thr Pro Asp Ala Thr Lys Gly Cys Pro 
                165                 170                 175     


Asp Val Gln Ala Ser Leu Pro Asp Ala Lys Ala Lys Ser Pro Pro Thr 
            180                 185                 190         


Met Val Asp Ser Leu Leu Ala Val Thr Leu Ala Gly Asn Leu Gly Leu 
        195                 200                 205             


Thr Phe Leu Arg Gly Ser Gln Thr Gln Ser His Pro Asp Leu Gly Thr 
    210                 215                 220                 


Glu Gly Cys Trp Asp Gln Leu Ser Ala Pro Arg Thr Phe Thr Leu Leu 
225                 230                 235                 240 


Asp Pro Lys Ala Ser Leu Leu Thr Met Ala Phe Leu Asn Gly Ala Leu 
                245                 250                 255     


Asp Gly Val Ile Leu Gly Asp Tyr Leu Ser Arg Thr Pro Glu Pro Arg 
            260                 265                 270         


Pro Ser Leu Ser His Leu Leu Ser Gln Tyr Tyr Gly Ala Gly Val Ala 
        275                 280                 285             


Arg Asp Pro Gly Phe Arg Ser Asn Phe Arg Arg Gln Asn Gly Ala Ala 
    290                 295                 300                 


Leu Thr Ser Ala Ser Ile Leu Ala Gln Gln Val Trp Gly Thr Leu Val 
305                 310                 315                 320 


Leu Leu Gln Arg Leu Glu Pro Val His Leu Gln Leu Gln Cys Met Ser 
                325                 330                 335     


Gln Glu Gln Leu Ala Gln Val Ala Ala Asn Ala Thr Lys Glu Phe Thr 
            340                 345                 350         


Glu Ala Phe Leu Gly Cys Pro Ala Ile His Pro Arg Cys Arg Trp Gly 
        355                 360                 365             


Ala Ala Pro Tyr Arg Gly Arg Pro Lys Leu Leu Gln Leu Pro Leu Gly 
    370                 375                 380                 


Phe Leu Tyr Val His His Thr Tyr Val Pro Ala Pro Pro Cys Thr Asp 
385                 390                 395                 400 


Phe Thr Arg Cys Ala Ala Asn Met Arg Ser Met Gln Arg Tyr His Gln 
                405                 410                 415     


Asp Thr Gln Gly Trp Gly Asp Ile Gly Tyr Ser Phe Val Val Gly Ser 
            420                 425                 430         


Asp Gly Tyr Val Tyr Glu Gly Arg Gly Trp His Trp Val Gly Ala His 
        435                 440                 445             


Thr Leu Gly His Asn Ser Arg Gly Phe Gly Val Ala Ile Val Gly Asn 
    450                 455                 460                 


Tyr Thr Ala Ala Leu Pro Thr Glu Ala Ala Leu Arg Thr Val Arg Asp 
465                 470                 475                 480 


Thr Leu Pro Ser Cys Ala Val Arg Ala Gly Leu Leu Arg Pro Asp Tyr 
                485                 490                 495     


Ala Leu Leu Gly His Arg Gln Leu Val Arg Thr Asp Cys Pro Gly Asp 
            500                 505                 510         


Ala Leu Phe Asp Leu Leu Arg Thr Trp Pro His Phe Thr Ala Thr Val 
        515                 520                 525             


Lys Pro Arg Pro Ala Arg Ser Val Ser Lys Arg Ser Arg Arg Glu Pro 
    530                 535                 540                 


Pro Pro Arg Thr Leu Pro Ala Thr Asp Leu Gln 
545                 550                 555 


<210>  1631
<211>  356
<212>  PRT
<213>  Homo Sapiens

<400>  1631

Asp Ser Ser Trp Asn Lys Thr Gln Ala Lys Gln Val Ser Glu Gly Leu 
1               5                   10                  15      


Gln Tyr Leu Phe Glu Asn Ile Ser Gln Leu Thr Glu Lys Gly Leu Pro 
            20                  25                  30          


Thr Asp Val Ser Thr Thr Val Ser Arg Lys Ala Trp Gly Ala Glu Ala 
        35                  40                  45              


Val Gly Cys Ser Ile Gln Leu Thr Thr Pro Val Asn Val Leu Val Ile 
    50                  55                  60                  


His His Val Pro Gly Leu Glu Cys His Asp Gln Thr Val Cys Ser Gln 
65                  70                  75                  80  


Arg Leu Arg Glu Leu Gln Ala His His Val His Asn Asn Ser Gly Cys 
                85                  90                  95      


Asp Val Ala Tyr Asn Phe Leu Val Gly Asp Asp Gly Arg Val Tyr Glu 
            100                 105                 110         


Gly Val Gly Trp Asn Ile Gln Gly Val His Thr Gln Gly Tyr Asn Asn 
        115                 120                 125             


Ile Ser Leu Gly Phe Ala Phe Phe Gly Thr Lys Lys Gly His Ser Pro 
    130                 135                 140                 


Ser Pro Ala Ala Leu Ser Ala Met Glu Asn Leu Ile Thr Tyr Ala Val 
145                 150                 155                 160 


Gln Lys Gly His Leu Ser Ser Ser Tyr Val Gln Pro Leu Leu Gly Lys 
                165                 170                 175     


Gly Glu Asn Cys Leu Ala Pro Arg Gln Lys Thr Ser Leu Lys Lys Ala 
            180                 185                 190         


Cys Pro Gly Val Val Pro Arg Ser Val Trp Gly Ala Arg Glu Thr His 
        195                 200                 205             


Cys Pro Arg Met Thr Leu Pro Ala Lys Tyr Gly Ile Ile Ile His Thr 
    210                 215                 220                 


Ala Gly Arg Thr Cys Asn Ile Ser Asp Glu Cys Arg Leu Leu Val Arg 
225                 230                 235                 240 


Asp Ile Gln Ser Phe Tyr Ile Asp Arg Leu Lys Ser Cys Asp Ile Gly 
                245                 250                 255     


Tyr Asn Phe Leu Val Gly Gln Asp Gly Ala Ile Tyr Glu Gly Val Gly 
            260                 265                 270         


Trp Asn Val Gln Gly Ser Ser Thr Pro Gly Tyr Asp Asp Ile Ala Leu 
        275                 280                 285             


Gly Ile Thr Phe Met Gly Thr Phe Thr Gly Ile Pro Pro Asn Ala Ala 
    290                 295                 300                 


Ala Leu Glu Ala Ala Gln Asp Leu Ile Gln Cys Ala Met Val Lys Gly 
305                 310                 315                 320 


Tyr Leu Thr Pro Asn Tyr Leu Leu Val Gly His Ser Asp Val Ala Arg 
                325                 330                 335     


Thr Leu Ser Pro Gly Gln Ala Leu Tyr Asn Ile Ile Ser Thr Trp Pro 
            340                 345                 350         


His Phe Lys His 
        355     


<210>  1632
<211>  436
<212>  PRT
<213>  Homo Sapiens

<400>  1632

Leu Thr Asp Glu Glu Lys Arg Leu Met Val Glu Leu His Asn Leu Tyr 
1               5                   10                  15      


Arg Ala Gln Val Ser Pro Thr Ala Ser Asp Met Leu His Met Arg Trp 
            20                  25                  30          


Asp Glu Glu Leu Ala Ala Phe Ala Lys Ala Tyr Ala Arg Gln Cys Val 
        35                  40                  45              


Trp Gly His Asn Lys Glu Arg Gly Arg Arg Gly Glu Asn Leu Phe Ala 
    50                  55                  60                  


Ile Thr Asp Glu Gly Met Asp Val Pro Leu Ala Met Glu Glu Trp His 
65                  70                  75                  80  


His Glu Arg Glu His Tyr Asn Leu Ser Ala Ala Thr Cys Ser Pro Gly 
                85                  90                  95      


Gln Met Cys Gly His Tyr Thr Gln Val Val Trp Ala Lys Thr Glu Arg 
            100                 105                 110         


Ile Gly Cys Gly Ser His Phe Cys Glu Lys Leu Gln Gly Val Glu Glu 
        115                 120                 125             


Thr Asn Ile Glu Leu Leu Val Cys Asn Tyr Glu Pro Pro Gly Asn Val 
    130                 135                 140                 


Lys Gly Lys Arg Pro Tyr Gln Glu Gly Thr Pro Cys Ser Gln Cys Pro 
145                 150                 155                 160 


Ser Gly Tyr His Cys Lys Asn Ser Leu Cys Glu Pro Ile Gly Ser Pro 
                165                 170                 175     


Glu Asp Ala Gln Asp Leu Pro Tyr Leu Val Thr Glu Ala Pro Ser Phe 
            180                 185                 190         


Arg Ala Thr Glu Ala Ser Asp Ser Arg Lys Met Gly Thr Pro Ser Ser 
        195                 200                 205             


Leu Ala Thr Gly Ile Pro Ala Phe Leu Val Thr Glu Val Ser Gly Ser 
    210                 215                 220                 


Leu Ala Thr Lys Ala Leu Pro Ala Val Glu Thr Gln Ala Pro Thr Ser 
225                 230                 235                 240 


Leu Ala Thr Lys Asp Pro Pro Ser Met Ala Thr Glu Ala Pro Pro Cys 
                245                 250                 255     


Val Thr Thr Glu Val Pro Ser Ile Leu Ala Ala His Ser Leu Pro Ser 
            260                 265                 270         


Leu Asp Glu Glu Pro Val Thr Phe Pro Lys Ser Thr His Val Pro Ile 
        275                 280                 285             


Pro Lys Ser Ala Asp Lys Val Thr Asp Lys Thr Lys Val Pro Ser Arg 
    290                 295                 300                 


Ser Pro Glu Asn Ser Leu Asp Pro Lys Met Ser Leu Thr Gly Ala Arg 
305                 310                 315                 320 


Glu Leu Leu Pro His Ala Gln Glu Glu Ala Glu Ala Glu Ala Glu Leu 
                325                 330                 335     


Pro Pro Ser Ser Glu Val Leu Ala Ser Val Phe Pro Ala Gln Asp Lys 
            340                 345                 350         


Pro Gly Glu Leu Gln Ala Thr Leu Asp His Thr Gly His Thr Ser Ser 
        355                 360                 365             


Lys Ser Leu Pro Asn Phe Pro Asn Thr Ser Ala Thr Ala Asn Ala Thr 
    370                 375                 380                 


Gly Gly Arg Ala Leu Ala Leu Gln Ser Ser Leu Pro Gly Ala Glu Gly 
385                 390                 395                 400 


Pro Asp Lys Pro Ser Val Val Ser Gly Leu Asn Ser Gly Pro Gly His 
                405                 410                 415     


Val Trp Gly Pro Leu Leu Gly Leu Leu Leu Leu Pro Pro Leu Val Leu 
            420                 425                 430         


Ala Gly Ile Phe 
        435     


<210>  1633
<211>  379
<212>  PRT
<213>  Homo Sapiens

<400>  1633

Ala Gly Arg His Pro Pro Val Val Leu Val Pro Gly Asp Leu Gly Asn 
1               5                   10                  15      


Gln Leu Glu Ala Lys Leu Asp Lys Pro Thr Val Val His Tyr Leu Cys 
            20                  25                  30          


Ser Lys Lys Thr Glu Ser Tyr Phe Thr Ile Trp Leu Asn Leu Glu Leu 
        35                  40                  45              


Leu Leu Pro Val Ile Ile Asp Cys Trp Ile Asp Asn Ile Arg Leu Val 
    50                  55                  60                  


Tyr Asn Lys Thr Ser Arg Ala Thr Gln Phe Pro Asp Gly Val Asp Val 
65                  70                  75                  80  


Arg Val Pro Gly Phe Gly Lys Thr Phe Ser Leu Glu Phe Leu Asp Pro 
                85                  90                  95      


Ser Lys Ser Ser Val Gly Ser Tyr Phe His Thr Met Val Glu Ser Leu 
            100                 105                 110         


Val Gly Trp Gly Tyr Thr Arg Gly Glu Asp Val Arg Gly Ala Pro Tyr 
        115                 120                 125             


Asp Trp Arg Arg Ala Pro Asn Glu Asn Gly Pro Tyr Phe Leu Ala Leu 
    130                 135                 140                 


Arg Glu Met Ile Glu Glu Met Tyr Gln Leu Tyr Gly Gly Pro Val Val 
145                 150                 155                 160 


Leu Val Ala His Ser Met Gly Asn Met Tyr Thr Leu Tyr Phe Leu Gln 
                165                 170                 175     


Arg Gln Pro Gln Ala Trp Lys Asp Lys Tyr Ile Arg Ala Phe Val Ser 
            180                 185                 190         


Leu Gly Ala Pro Trp Gly Gly Val Ala Lys Thr Leu Arg Val Leu Ala 
        195                 200                 205             


Ser Gly Asp Asn Asn Arg Ile Pro Val Ile Gly Pro Leu Lys Ile Arg 
    210                 215                 220                 


Glu Gln Gln Arg Ser Ala Val Ser Thr Ser Trp Leu Leu Pro Tyr Asn 
225                 230                 235                 240 


Tyr Thr Trp Ser Pro Glu Lys Val Phe Val Gln Thr Pro Thr Ile Asn 
                245                 250                 255     


Tyr Thr Leu Arg Asp Tyr Arg Lys Phe Phe Gln Asp Ile Gly Phe Glu 
            260                 265                 270         


Asp Gly Trp Leu Met Arg Gln Asp Thr Glu Gly Leu Val Glu Ala Thr 
        275                 280                 285             


Met Pro Pro Gly Val Gln Leu His Cys Leu Tyr Gly Thr Gly Val Pro 
    290                 295                 300                 


Thr Pro Asp Ser Phe Tyr Tyr Glu Ser Phe Pro Asp Arg Asp Pro Lys 
305                 310                 315                 320 


Ile Cys Phe Gly Asp Gly Asp Gly Thr Val Asn Leu Lys Ser Ala Leu 
                325                 330                 335     


Gln Cys Gln Ala Trp Gln Ser Arg Gln Glu His Gln Val Leu Leu Gln 
            340                 345                 350         


Glu Leu Pro Gly Ser Glu His Ile Glu Met Leu Ala Asn Ala Thr Thr 
        355                 360                 365             


Leu Ala Tyr Leu Lys Arg Val Leu Leu Gly Pro 
    370                 375                 


<210>  1634
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  1634

Ser Phe Trp Gln Phe Gln Arg Arg Val Lys His Ile Thr Gly Arg Ser 
1               5                   10                  15      


Ala Phe Phe Ser Tyr Tyr Gly Tyr Gly Cys Tyr Cys Gly Leu Gly Asp 
            20                  25                  30          


Lys Gly Ile Pro Val Asp Asp Thr Asp Arg His Ser Pro Ser Ser Pro 
        35                  40                  45              


Ser Pro Tyr Glu Lys Leu Lys Glu Phe Ser Cys Gln Pro Val Leu Asn 
    50                  55                  60                  


Ser Tyr Gln Phe His Ile Val Asn Gly Ala Val Val Cys Gly Cys Thr 
65                  70                  75                  80  


Leu Gly Pro Gly Ala Ser Cys His Cys Arg Leu Lys Ala Cys Glu Cys 
                85                  90                  95      


Asp Lys Gln Ser Val His Cys Phe Lys Glu Ser Leu Pro Thr Tyr Glu 
            100                 105                 110         


Lys Asn Phe Lys Gln Phe Ser Ser Gln Pro Arg Cys Gly Arg His Lys 
        115                 120                 125             


Pro Trp Cys 
    130     


<210>  1635
<211>  515
<212>  PRT
<213>  Homo Sapiens

<400>  1635

Gly Val Tyr Tyr Ala Thr Ala Tyr Trp Met Pro Ala Glu Lys Thr Val 
1               5                   10                  15      


Gln Val Lys Asn Val Met Asp Lys Asn Gly Asp Ala Tyr Gly Phe Tyr 
            20                  25                  30          


Asn Asn Ser Val Lys Thr Thr Gly Trp Gly Ile Leu Glu Ile Arg Ala 
        35                  40                  45              


Gly Tyr Gly Ser Gln Thr Leu Ser Asn Glu Ile Ile Met Phe Val Ala 
    50                  55                  60                  


Gly Phe Leu Glu Gly Tyr Leu Thr Ala Pro His Met Asn Asp His Tyr 
65                  70                  75                  80  


Thr Asn Leu Tyr Pro Gln Leu Ile Thr Lys Pro Ser Ile Met Asp Lys 
                85                  90                  95      


Val Gln Asp Phe Met Glu Lys Gln Asp Lys Trp Thr Arg Lys Asn Ile 
            100                 105                 110         


Lys Glu Tyr Lys Thr Asp Ser Phe Trp Arg His Thr Gly Tyr Val Met 
        115                 120                 125             


Ala Gln Ile Asp Gly Leu Tyr Val Gly Ala Lys Lys Arg Ala Ile Leu 
    130                 135                 140                 


Glu Gly Thr Lys Pro Met Thr Leu Phe Gln Ile Gln Phe Leu Asn Ser 
145                 150                 155                 160 


Val Gly Asp Leu Leu Asp Leu Ile Pro Ser Leu Ser Pro Thr Lys Asn 
                165                 170                 175     


Gly Ser Leu Lys Val Phe Lys Arg Trp Asp Met Gly His Cys Ser Ala 
            180                 185                 190         


Leu Ile Lys Val Leu Pro Gly Phe Glu Asn Ile Leu Phe Ala His Ser 
        195                 200                 205             


Ser Trp Tyr Thr Tyr Ala Ala Met Leu Arg Ile Tyr Lys His Trp Asp 
    210                 215                 220                 


Phe Asn Val Ile Asp Lys Asp Thr Ser Ser Ser Arg Leu Ser Phe Ser 
225                 230                 235                 240 


Ser Tyr Pro Gly Phe Leu Glu Ser Leu Asp Asp Phe Tyr Ile Leu Ser 
                245                 250                 255     


Ser Gly Leu Ile Leu Leu Gln Thr Thr Asn Ser Val Phe Asn Lys Thr 
            260                 265                 270         


Leu Leu Lys Gln Val Ile Pro Glu Thr Leu Leu Ser Trp Gln Arg Val 
        275                 280                 285             


Arg Val Ala Asn Met Met Ala Asp Ser Gly Lys Arg Trp Ala Asp Ile 
    290                 295                 300                 


Phe Ser Lys Tyr Asn Ser Gly Thr Tyr Asn Asn Gln Tyr Met Val Leu 
305                 310                 315                 320 


Asp Leu Lys Lys Val Lys Leu Asn His Ser Leu Asp Lys Gly Thr Leu 
                325                 330                 335     


Tyr Ile Val Glu Gln Ile Pro Thr Tyr Val Glu Tyr Ser Glu Gln Thr 
            340                 345                 350         


Asp Val Leu Arg Lys Gly Tyr Trp Pro Ser Tyr Asn Val Pro Phe His 
        355                 360                 365             


Glu Lys Ile Tyr Asn Trp Ser Gly Tyr Pro Leu Leu Val Gln Lys Leu 
    370                 375                 380                 


Gly Leu Asp Tyr Ser Tyr Asp Leu Ala Pro Arg Ala Lys Ile Phe Arg 
385                 390                 395                 400 


Arg Asp Gln Gly Lys Val Thr Asp Thr Ala Ser Met Lys Tyr Ile Met 
                405                 410                 415     


Arg Tyr Asn Asn Tyr Lys Lys Asp Pro Tyr Ser Arg Gly Asp Pro Cys 
            420                 425                 430         


Asn Thr Ile Cys Cys Arg Glu Asp Leu Asn Ser Pro Asn Pro Ser Pro 
        435                 440                 445             


Gly Gly Cys Tyr Asp Thr Lys Val Ala Asp Ile Tyr Leu Ala Ser Gln 
    450                 455                 460                 


Tyr Thr Ser Tyr Ala Ile Ser Gly Pro Thr Val Gln Gly Gly Leu Pro 
465                 470                 475                 480 


Val Phe Arg Trp Asp Arg Phe Asn Lys Thr Leu His Gln Gly Met Pro 
                485                 490                 495     


Glu Val Tyr Asn Phe Asp Phe Ile Thr Met Lys Pro Ile Leu Lys Leu 
            500                 505                 510         


Asp Ile Lys 
        515 


<210>  1636
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  1636

Ile Pro Ala Pro Gly Gly Arg Trp Ala Arg Asp Gly Gln Val Pro Pro 
1               5                   10                  15      


Ala Ser Arg Ser Arg Ser Val Leu Leu Asp Val Ser Ala Gly Gln Leu 
            20                  25                  30          


Leu Met Val Asp Gly Arg His Pro Asp Ala Val Ala Trp Ala Asn Leu 
        35                  40                  45              


Thr Asn Ala Ile Arg Glu Thr Gly Trp Ala Phe Leu Glu Leu Gly Thr 
    50                  55                  60                  


Ser Gly Gln Tyr Asn Asp Ser Leu Gln Ala Tyr Ala Ala Gly Val Val 
65                  70                  75                  80  


Glu Ala Ala Val Ser Glu Glu Leu Ile Tyr Met His Trp Met Asn Thr 
                85                  90                  95      


Val Val Asn Tyr Cys Gly Pro Phe Glu Tyr Glu Val Gly Tyr Cys Glu 
            100                 105                 110         


Arg Leu Lys Ser Phe Leu Glu Ala Asn Leu Glu Trp Met Gln Glu Glu 
        115                 120                 125             


Met Glu Ser Asn Pro Asp Ser Pro Tyr Trp His Gln Val Arg Leu Thr 
    130                 135                 140                 


Leu Leu Gln Leu Lys Gly Leu Glu Asp Ser Tyr Glu Gly Arg Val Ser 
145                 150                 155                 160 


Phe Pro Ala Gly Lys Phe Thr Ile Lys Pro Leu Gly Phe Leu Leu Leu 
                165                 170                 175     


Gln Leu Ser Gly Asp Leu Glu Asp Leu Glu Leu Ala Leu Asn Lys Thr 
            180                 185                 190         


Lys Ile Lys Pro Ser Leu Gly Ser Gly Ser 
        195                 200         


<210>  1637
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  1637

Thr Phe Ile Arg Tyr Ser Ser Thr Cys Phe Thr Phe Asp Glu Tyr Tyr 
1               5                   10                  15      


Thr Ile Thr Leu Asp Ile Lys Ala Ser Ser His Ile Tyr Glu Ser Asn 
            20                  25                  30          


Ala Val Tyr Ser Val Phe Val Pro Val Asn Asp Ser Val Tyr Ala Val 
        35                  40                  45              


Val Met Lys Thr Leu Asp Glu Asn Ser Asp Ser Ala Gly Leu Trp Gln 
    50                  55                  60                  


Arg Ala Asp Lys Asn Cys Tyr Ser Asn Ser Thr Tyr Tyr Val Lys Asp 
65                  70                  75                  80  


Gln Tyr Met Thr Val Leu Glu Ala Gln Trp Gln Ala Pro Glu Pro Glu 
                85                  90                  95      


Asn Ile Thr Glu Val Glu Ile Gln Ala Phe Thr Val Gln Ile Arg Ala 
            100                 105                 110         


Leu Pro Ile Leu Ser Thr Leu Lys Leu Arg Glu Lys Leu Ser Thr Leu 
        115                 120                 125             


Ala Leu Ala Ala Lys Ile Pro Gln Ser Ser Ala Phe Lys Pro Phe Phe 
    130                 135                 140                 


Met Ile Thr Pro Lys Ser Ile Arg Leu Glu Gly Leu Ala Asn Gln Val 
145                 150                 155                 160 


Phe Ser 
        


<210>  1638
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1638

Glu Pro Leu Asp Asp Tyr Val Asn Ala Gln Gly Ala Ser Leu Phe Ser 
1               5                   10                  15      


Val Thr Lys Lys Gln Leu Gly Ala Gly Ser Arg Glu Glu Cys Ala Ala 
            20                  25                  30          


Lys Cys Glu Glu Asp Lys Glu Phe Thr Cys Arg Ala Phe Gln Tyr His 
        35                  40                  45              


Ser Lys Glu Gln Gln Cys Val Ile Met Ala Glu Asn Lys Lys Ser Ser 
    50                  55                  60                  


Ile Ile Ile Arg Met Arg Asp Val Val Leu Phe Glu Lys 
65                  70                  75          


<210>  1639
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1639

Glu Pro Leu Asp Asp Tyr Val Asn Thr Gln Gly Pro Ser Leu Phe Ser 
1               5                   10                  15      


Val Thr Lys Lys Gln Leu Gly Ala Gly Ser Arg Glu Glu Cys Ala Ala 
            20                  25                  30          


Lys Cys Glu Glu Asp Lys Glu Phe Thr Cys Arg Ala Phe Gln Tyr His 
        35                  40                  45              


Ser Lys Glu Gln Gln Cys Val Ile Met Ala Glu Asn Arg Lys Ser Ser 
    50                  55                  60                  


Ile Ile Ile Arg Met Arg Asp Ala Val Leu Phe Glu Lys 
65                  70                  75          


<210>  1640
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  1640

Met Gly Pro Arg Ser Gly Glu His Gln Arg Ala Ser Arg Ile Pro Ser 
1               5                   10                  15      


Gln Phe Ser Lys Glu Glu Arg Val Ala Met Lys Glu Ala Leu Lys Gly 
            20                  25                  30          


Ala Ile Gln Ile Pro Thr Val Thr Phe Ser Ser Glu Lys Ser Asn Thr 
        35                  40                  45              


Thr Ala Leu Ala Glu Phe Gly Lys Tyr Ile His Lys Val Phe Pro Thr 
    50                  55                  60                  


Val Val Ser Thr Ser Phe Ile Gln His Glu Val Val Glu Glu Tyr Ser 
65                  70                  75                  80  


His Leu Phe Thr Ile Gln Gly Ser Asp Pro Ser Leu Gln Pro Tyr Leu 
                85                  90                  95      


Leu Met Ala His Phe Asp Val Val Pro Ala Pro Glu Glu Gly Trp Glu 
            100                 105                 110         


Val Pro Pro Phe Ser Gly Leu Glu Arg Asp Gly Ile Ile Tyr Gly Arg 
        115                 120                 125             


Gly Thr Leu Asp Asp Lys Asn Ser Val Met Ala Leu Leu Gln Ala Leu 
    130                 135                 140                 


Glu Leu Leu Leu Ile Arg Lys Tyr Ile Pro Arg Arg Ser Phe Phe Ile 
145                 150                 155                 160 


Ser Leu Gly His Asp Glu Glu Ser Ser Gly Thr Gly Ala Gln Arg Ile 
                165                 170                 175     


Ser Ala Leu Leu Gln Ser Arg Gly Val Gln Leu Ala Phe Ile Val Asp 
            180                 185                 190         


Glu Gly Gly Phe Ile Leu Asp Asp Phe Ile Pro Asn Phe Lys Lys Pro 
        195                 200                 205             


Ile Ala Leu Ile Ala Val Ser Glu Lys Gly Ser Met Asn Leu Met Leu 
    210                 215                 220                 


Gln Val Asn Met Thr Ser Gly His Ser Ser Ala Pro Pro Lys Glu Thr 
225                 230                 235                 240 


Ser Ile Gly Ile Leu Ala Ala Ala Val Ser Arg Leu Glu Gln Thr Pro 
                245                 250                 255     


Met Pro Ile Ile Phe Gly Ser Gly Thr Val Val Thr Val Leu Gln Gln 
            260                 265                 270         


Leu Ala Asn Glu Phe Pro Phe Pro Val Asn Ile Ile Leu Ser Asn Pro 
        275                 280                 285             


Trp Leu Phe Glu Pro Leu Ile Ser Arg Phe Met Glu Arg Asn Pro Leu 
    290                 295                 300                 


Thr Asn Ala Ile Ile Arg Thr Thr Thr Ala Leu Thr Ile Phe Lys Ala 
305                 310                 315                 320 


Gly Val Lys Phe Asn Val Ile Pro Pro Val Ala Gln Ala Thr Val Asn 
                325                 330                 335     


Phe Arg Ile His Pro Gly Gln Thr Val Gln Glu Val Leu Glu Leu Thr 
            340                 345                 350         


Lys Asn Ile Val Ala Asp Asn Arg Val Gln Phe His Val Leu Ser Ala 
        355                 360                 365             


Phe Asp Pro Leu Pro Val Ser Pro Ser Asp Asp Lys Ala Leu Gly Tyr 
    370                 375                 380                 


Gln Leu Leu Arg Gln Thr Val Gln Ser Val Phe Pro Glu Val Asn Ile 
385                 390                 395                 400 


Thr Ala Pro Val Thr Ser Ile Gly Asn Thr Asp Ser Arg Phe Phe Thr 
                405                 410                 415     


Asn Leu Thr Thr Gly Ile Tyr Arg Phe Tyr Pro Ile Tyr Ile Gln Pro 
            420                 425                 430         


Glu Asp Phe Lys Arg Ile His Gly Val Asn Glu Lys Ile Ser Val Gln 
        435                 440                 445             


Ala Tyr Glu Thr Gln Val Lys Phe Ile Phe Glu Leu Ile Gln Asn Ala 
    450                 455                 460                 


Asp Thr Asp Gln Glu Pro Val Ser His Leu His Lys Leu 
465                 470                 475         


<210>  1641
<211>  450
<212>  PRT
<213>  Homo Sapiens

<400>  1641

Lys Glu Val Cys Tyr Glu Asp Leu Gly Cys Phe Ser Asp Thr Glu Pro 
1               5                   10                  15      


Trp Gly Gly Thr Ala Ile Arg Pro Leu Lys Ile Leu Pro Trp Ser Pro 
            20                  25                  30          


Glu Lys Ile Gly Thr Arg Phe Leu Leu Tyr Thr Asn Glu Asn Pro Asn 
        35                  40                  45              


Asn Phe Gln Ile Leu Leu Leu Ser Asp Pro Ser Thr Ile Glu Ala Ser 
    50                  55                  60                  


Asn Phe Gln Met Asp Arg Lys Thr Arg Phe Ile Ile His Gly Phe Ile 
65                  70                  75                  80  


Asp Lys Gly Asp Glu Ser Trp Val Thr Asp Met Cys Lys Lys Leu Phe 
                85                  90                  95      


Glu Val Glu Glu Val Asn Cys Ile Cys Val Asp Trp Lys Lys Gly Ser 
            100                 105                 110         


Gln Ala Thr Tyr Thr Gln Ala Ala Asn Asn Val Arg Val Val Gly Ala 
        115                 120                 125             


Gln Val Ala Gln Met Leu Asp Ile Leu Leu Thr Glu Tyr Ser Tyr Pro 
    130                 135                 140                 


Pro Ser Lys Val His Leu Ile Gly His Ser Leu Gly Ala His Val Ala 
145                 150                 155                 160 


Gly Glu Ala Gly Ser Lys Thr Pro Gly Leu Ser Arg Ile Thr Gly Leu 
                165                 170                 175     


Asp Pro Val Glu Ala Ser Phe Glu Ser Thr Pro Glu Glu Val Arg Leu 
            180                 185                 190         


Asp Pro Ser Asp Ala Asp Phe Val Asp Val Ile His Thr Asp Ala Ala 
        195                 200                 205             


Pro Leu Ile Pro Phe Leu Gly Phe Gly Thr Asn Gln Gln Met Gly His 
    210                 215                 220                 


Leu Asp Phe Phe Pro Asn Gly Gly Glu Ser Met Pro Gly Cys Lys Lys 
225                 230                 235                 240 


Asn Ala Leu Ser Gln Ile Val Asp Leu Asp Gly Ile Trp Ala Gly Thr 
                245                 250                 255     


Arg Asp Phe Val Ala Cys Asn His Leu Arg Ser Tyr Lys Tyr Tyr Leu 
            260                 265                 270         


Glu Ser Ile Leu Asn Pro Asp Gly Phe Ala Ala Tyr Pro Cys Thr Ser 
        275                 280                 285             


Tyr Lys Ser Phe Glu Ser Asp Lys Cys Phe Pro Cys Pro Asp Gln Gly 
    290                 295                 300                 


Cys Pro Gln Met Gly His Tyr Ala Asp Lys Phe Ala Gly Arg Thr Ser 
305                 310                 315                 320 


Glu Glu Gln Gln Lys Phe Phe Leu Asn Thr Gly Glu Ala Ser Asn Phe 
                325                 330                 335     


Ala Arg Trp Arg Tyr Gly Val Ser Ile Thr Leu Ser Gly Arg Thr Ala 
            340                 345                 350         


Thr Gly Gln Ile Lys Val Ala Leu Phe Gly Asn Lys Gly Asn Thr His 
        355                 360                 365             


Gln Tyr Ser Ile Phe Arg Gly Ile Leu Lys Pro Gly Ser Thr His Ser 
    370                 375                 380                 


Tyr Glu Phe Asp Ala Lys Leu Asp Val Gly Thr Ile Glu Lys Val Lys 
385                 390                 395                 400 


Phe Leu Trp Asn Asn Asn Val Ile Asn Pro Thr Leu Pro Lys Val Gly 
                405                 410                 415     


Ala Thr Lys Ile Thr Val Gln Lys Gly Glu Glu Lys Thr Val Tyr Asn 
            420                 425                 430         


Phe Cys Ser Glu Asp Thr Val Arg Glu Asp Thr Leu Leu Thr Leu Thr 
        435                 440                 445             


Pro Cys 
    450 


<210>  1642
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  1642

Leu His Leu Asp Ala Ser Ile His Pro Phe Arg Leu Pro Phe Ser Ser 
1               5                   10                  15      


Lys Pro Phe Leu Leu Ile Pro Met Ser Asn Thr Thr Leu Pro His Thr 
            20                  25                  30          


Ala Trp Pro Leu Ser Phe Leu His Gln Thr Val Ser Thr Leu Lys Ala 
        35                  40                  45              


Val Ala Val Thr His Ser Leu Trp His Leu Gln Ile Pro Val Asp Cys 
    50                  55                  60                  


Gln Ala Cys Asn Arg Lys Ser Lys Lys Ile Tyr Cys 
65                  70                  75      


<210>  1643
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  1643

Met Ser Ser Glu Lys Ser Gly Leu Pro Asp Ser Val Pro His Thr Ser 
1               5                   10                  15      


Pro Pro Pro Tyr Asn Ala Pro Gln Pro Pro Ala Glu Pro Pro Ala Pro 
            20                  25                  30          


Pro Pro Gln Ala Ala Pro Ser Ser His His His His His His His Tyr 
        35                  40                  45              


His Gln Ser Gly Thr Ala Thr Leu Pro Arg Leu Gly Ala Gly Gly Leu 
    50                  55                  60                  


Ala Ser Ser Ala Ala Thr Ala Gln Arg Gly Pro Ser Ser Ser Ala Thr 
65                  70                  75                  80  


Leu Pro Arg Pro Pro His His Ala Pro Pro Gly Pro Ala Ala Gly Ala 
                85                  90                  95      


Pro Pro Pro Gly Cys Ala Thr Leu Pro Arg Met Pro Pro Asp Pro Tyr 
            100                 105                 110         


Leu Gln Glu Thr Arg Phe Glu Gly Pro Leu Pro Pro Pro Pro Pro Ala 
        115                 120                 125             


Ala Ala Ala Pro Pro Pro Pro Ala Pro Ala Gln Thr Ala Gln Ala Pro 
    130                 135                 140                 


Gly Phe Val Val Pro Thr His Ala Gly Thr Val Gly Thr Leu Pro Leu 
145                 150                 155                 160 


Gly Gly Tyr Val Ala Pro Gly Tyr Pro Leu Gln Leu Gln Pro Cys Thr 
                165                 170                 175     


Ala Tyr Val Pro Val Tyr Pro Val Gly Thr Pro Tyr Ala Gly Gly Thr 
            180                 185                 190         


Pro Gly Gly Thr Gly Val Thr Ser Thr Leu Pro Pro Pro Pro Gln Gly 
        195                 200                 205             


Pro Gly Leu Ala Leu Leu Glu Pro Arg Arg Pro Pro His Asp Tyr 
    210                 215                 220             


<210>  1644
<211>  364
<212>  PRT
<213>  Homo Sapiens

<400>  1644

Gln Val Ser Pro Tyr Ser Ala Pro Trp Lys Pro Thr Trp Pro Ala Tyr 
1               5                   10                  15      


Arg Leu Pro Val Val Leu Pro Gln Ser Thr Leu Asn Leu Ala Lys Pro 
            20                  25                  30          


Asp Phe Gly Ala Glu Ala Lys Leu Glu Val Ser Ser Ser Cys Gly Pro 
        35                  40                  45              


Gln Cys His Lys Gly Thr Pro Leu Pro Thr Tyr Glu Glu Ala Lys Gln 
    50                  55                  60                  


Tyr Leu Ser Tyr Glu Thr Leu Tyr Ala Asn Gly Ser Arg Thr Glu Thr 
65                  70                  75                  80  


Gln Val Gly Ile Tyr Ile Leu Ser Ser Ser Gly Asp Gly Ala Gln His 
                85                  90                  95      


Arg Asp Ser Gly Ser Ser Gly Lys Ser Arg Arg Lys Arg Gln Ile Tyr 
            100                 105                 110         


Gly Tyr Asp Ser Arg Phe Ser Ile Phe Gly Lys Asp Phe Leu Leu Asn 
        115                 120                 125             


Tyr Pro Phe Ser Thr Ser Val Lys Leu Ser Thr Gly Cys Thr Gly Thr 
    130                 135                 140                 


Leu Val Ala Glu Lys His Val Leu Thr Ala Ala His Cys Ile His Asp 
145                 150                 155                 160 


Gly Lys Thr Tyr Val Lys Gly Thr Gln Lys Leu Arg Val Gly Phe Leu 
                165                 170                 175     


Lys Pro Lys Phe Lys Asp Gly Gly Arg Gly Ala Asn Asp Ser Thr Ser 
            180                 185                 190         


Ala Met Pro Glu Gln Met Lys Phe Gln Trp Ile Arg Val Lys Arg Thr 
        195                 200                 205             


His Val Pro Lys Gly Trp Ile Lys Gly Asn Ala Asn Asp Ile Gly Met 
    210                 215                 220                 


Asp Tyr Asp Tyr Ala Leu Leu Glu Leu Lys Lys Pro His Lys Arg Lys 
225                 230                 235                 240 


Phe Met Lys Ile Gly Val Ser Pro Pro Ala Lys Gln Leu Pro Gly Gly 
                245                 250                 255     


Arg Ile His Phe Ser Gly Tyr Asp Asn Asp Arg Pro Gly Asn Leu Val 
            260                 265                 270         


Tyr Arg Phe Cys Asp Val Lys Asp Glu Thr Tyr Asp Leu Leu Tyr Gln 
        275                 280                 285             


Gln Cys Asp Ala Gln Pro Gly Ala Ser Gly Ser Gly Val Tyr Val Arg 
    290                 295                 300                 


Met Trp Lys Arg Gln Gln Gln Lys Trp Glu Arg Lys Ile Ile Gly Ile 
305                 310                 315                 320 


Phe Ser Gly His Gln Trp Val Asp Met Asn Gly Ser Pro Gln Asp Phe 
                325                 330                 335     


Asn Val Ala Val Arg Ile Thr Pro Leu Lys Tyr Ala Gln Ile Cys Tyr 
            340                 345                 350         


Trp Ile Lys Gly Asn Tyr Leu Asp Cys Arg Glu Gly 
        355                 360                 


<210>  1645
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  1645

Met Val Gly Gly Gln Asp Thr Gln Glu Gly Glu Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Ile Gln Arg Asn Gly Ser His Phe Cys Gly Gly Ser Leu Ile Ala 
            20                  25                  30          


Glu Gln Trp Val Leu Thr Ala Ala His Cys Phe Arg Asn Thr Ser Glu 
        35                  40                  45              


Thr Ser Leu Tyr Gln Val Leu Leu Gly Ala Arg Gln Leu Val Gln Pro 
    50                  55                  60                  


Gly Pro His Ala Met Tyr Ala Arg Val Arg Gln Val Glu Ser Asn Pro 
65                  70                  75                  80  


Leu Tyr Gln Gly Thr Ala Ser Ser Ala Asp Val Ala Leu Val Glu Leu 
                85                  90                  95      


Glu Ala Pro Val Pro Phe Thr Asn Tyr Ile Leu Pro Val Cys Leu Pro 
            100                 105                 110         


Asp Pro Ser Val Ile Phe Glu Thr Gly Met Asn Cys Trp Val Thr Gly 
        115                 120                 125             


Trp Gly Ser Pro Ser Glu Glu Asp Leu Leu Pro Glu Pro Arg Ile Leu 
    130                 135                 140                 


Gln Lys Leu Ala Val Pro Ile Ile Asp Thr Pro Lys Cys Asn Leu Leu 
145                 150                 155                 160 


Tyr Ser Lys Asp Thr Glu Phe Gly Tyr Gln Pro Lys Thr Ile Lys Asn 
                165                 170                 175     


Asp Met Leu Cys Ala Gly Phe Glu Glu Gly Lys Lys Asp Ala Cys Lys 
            180                 185                 190         


Gly Asp Ser Gly Gly Pro Leu Val Cys Leu Val Gly Gln Ser Trp Leu 
        195                 200                 205             


Gln Ala Gly Val Ile Ser Trp Gly Glu Gly Cys Ala Arg Gln Asn Arg 
    210                 215                 220                 


Pro Gly Val Tyr Ile Arg Val Thr Ala His His Asn Trp Ile His Arg 
225                 230                 235                 240 


Ile Ile Pro Lys Leu Gln Phe Gln Pro Ala Arg Leu Gly Gly Gln Lys 
                245                 250                 255     


<210>  1646
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  1646

Ile Val Gly Gly Tyr Thr Cys Glu Glu Asn Ser Leu Pro Tyr Gln Val 
1               5                   10                  15      


Ser Leu Asn Ser Gly Ser His Phe Cys Gly Gly Ser Leu Ile Ser Glu 
            20                  25                  30          


Gln Trp Val Val Ser Ala Ala His Cys Tyr Lys Thr Arg Ile Gln Val 
        35                  40                  45              


Arg Leu Gly Glu His Asn Ile Lys Val Leu Glu Gly Asn Glu Gln Phe 
    50                  55                  60                  


Ile Asn Ala Ala Lys Ile Ile Arg His Pro Lys Tyr Asn Arg Asp Thr 
65                  70                  75                  80  


Leu Asp Asn Asp Ile Met Leu Ile Lys Leu Ser Ser Pro Ala Val Ile 
                85                  90                  95      


Asn Ala Arg Val Ser Thr Ile Ser Leu Pro Thr Thr Pro Pro Ala Ala 
            100                 105                 110         


Gly Thr Glu Cys Leu Ile Ser Gly Trp Gly Asn Thr Leu Ser Phe Gly 
        115                 120                 125             


Ala Asp Tyr Pro Asp Glu Leu Lys Cys Leu Asp Ala Pro Val Leu Thr 
    130                 135                 140                 


Gln Ala Glu Cys Lys Ala Ser Tyr Pro Gly Lys Ile Thr Asn Ser Met 
145                 150                 155                 160 


Phe Cys Val Gly Phe Leu Glu Gly Gly Lys Asp Ser Cys Gln Arg Asp 
                165                 170                 175     


Ser Gly Gly Pro Val Val Cys Asn Gly Gln Leu Gln Gly Val Val Ser 
            180                 185                 190         


Trp Gly His Gly Cys Ala Trp Lys Asn Arg Pro Gly Val Tyr Thr Lys 
        195                 200                 205             


Val Tyr Asn Tyr Val Asp Trp Ile Lys Asp Thr Ile Ala Ala Asn Ser 
    210                 215                 220                 


<210>  1647
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  1647

Val Pro Phe Asp Asp Asp Asp Lys Ile Val Gly Gly Tyr Thr Cys Glu 
1               5                   10                  15      


Glu Asn Ser Val Pro Tyr Gln Val Ser Leu Asn Ser Gly Ser His Phe 
            20                  25                  30          


Cys Gly Gly Ser Leu Ile Ser Glu Gln Trp Val Val Ser Ala Gly His 
        35                  40                  45              


Cys Tyr Lys Pro His Ile Gln Val Arg Leu Gly Glu His Asn Ile Glu 
    50                  55                  60                  


Val Leu Glu Gly Asn Glu Gln Phe Ile Asn Ala Ala Lys Ile Ile Arg 
65                  70                  75                  80  


His Pro Lys Tyr Asn Arg Ile Ile Leu Asn Asn Asp Ile Met Leu Ile 
                85                  90                  95      


Lys Leu Ser Thr Pro Ala Val Ile Asn Ala His Val Ser Thr Ile Ser 
            100                 105                 110         


Leu Pro Thr Ala Pro Pro Ala Ala Gly Thr Glu Cys Leu Ile Ser Gly 
        115                 120                 125             


Trp Gly Asn Thr Leu Ser Ser Gly Ala Asp Tyr Pro Asp Glu Leu Gln 
    130                 135                 140                 


Cys Leu Asp Ala Pro Val Leu Thr Gln Ala Lys Cys Lys Ala Ser Tyr 
145                 150                 155                 160 


Pro Leu Lys Ile Thr Ser Asn Met Phe Cys Val Gly Phe Leu Glu Gly 
                165                 170                 175     


Gly Lys Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Val Val Cys Asn 
            180                 185                 190         


Gly Gln Leu Gln Gly Ile Val Ser Trp Gly Tyr Gly Cys Ala Gln Lys 
        195                 200                 205             


Arg Arg Pro Gly Val Tyr Thr Lys Val Tyr Asn Tyr Val Asp Trp Ile 
    210                 215                 220                 


Lys Asp Thr Ile Ala Ala Asn Ser 
225                 230         


<210>  1648
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  1648

Val Ala Gly Gly Val Glu Ser Ala Arg Gly Arg Trp Pro Trp Gln Ala 
1               5                   10                  15      


Ser Leu Arg Leu Arg Arg Arg His Arg Cys Gly Gly Ser Leu Leu Ser 
            20                  25                  30          


Arg Arg Trp Val Leu Ser Ala Ala His Cys Phe Gln Lys His Tyr Tyr 
        35                  40                  45              


Pro Ser Glu Trp Thr Val Gln Leu Gly Glu Leu Thr Ser Arg Pro Thr 
    50                  55                  60                  


Pro Trp Asn Leu Arg Ala Tyr Ser Ser Arg Tyr Lys Val Gln Asp Ile 
65                  70                  75                  80  


Ile Val Asn Pro Asp Ala Leu Gly Val Leu Arg Asn Asp Ile Ala Leu 
                85                  90                  95      


Leu Arg Leu Ala Ser Ser Val Thr Tyr Asn Ala Tyr Ile Gln Pro Ile 
            100                 105                 110         


Cys Ile Glu Ser Ser Thr Phe Asn Phe Val His Arg Pro Asp Cys Trp 
        115                 120                 125             


Val Thr Gly Trp Gly Leu Ile Ser Pro Ser Gly Thr Pro Leu Pro Pro 
    130                 135                 140                 


Pro Tyr Asn Leu Arg Glu Ala Gln Val Thr Ile Leu Asn Asn Thr Arg 
145                 150                 155                 160 


Cys Asn Tyr Leu Phe Glu Gln Pro Ser Ser Arg Ser Met Ile Trp Asp 
                165                 170                 175     


Ser Met Phe Cys Ala Gly Ala Glu Asp Gly Ser Val Asp Thr Cys Lys 
            180                 185                 190         


Gly Asp Ser Gly Gly Pro Leu Val Cys Asp Lys Asp Gly Leu Trp Tyr 
        195                 200                 205             


Gln Val Gly Ile Val Ser Trp Gly Met Asp Cys Gly Gln Pro Asn Arg 
    210                 215                 220                 


Pro Gly Val Tyr Thr Asn Ile Ser Val Tyr Phe His Trp Ile Arg Arg 
225                 230                 235                 240 


Val Met Ser His Ser 
                245 


<210>  1649
<211>  317
<212>  PRT
<213>  Homo Sapiens

<400>  1649

Gly Arg Val Gly Ala Gln Gly Gly Val Ala Leu Leu Phe Pro Ser Ala 
1               5                   10                  15      


Leu Pro Ser Gly Pro Gly Gly Gln Asp Pro Gly Ala Ser Gly Trp Glu 
            20                  25                  30          


Pro Pro Pro Val Gly Ala Pro Gly Ser Pro Ala Ala Pro Gln Ser Arg 
        35                  40                  45              


Gly Asn Ala Val Arg Pro Ala Ser Val Leu Leu Pro Ser Ala Cys Gly 
    50                  55                  60                  


Gln Arg Thr Ser Arg Ile Thr Gly Gly Leu Pro Ala Pro Asp Arg Lys 
65                  70                  75                  80  


Trp Pro Trp Gln Val Ser Leu Gln Thr Ser Asn Arg His Ile Cys Gly 
                85                  90                  95      


Gly Ser Leu Ile Ala Arg His Trp Val Leu Thr Ala Ala His Cys Ile 
            100                 105                 110         


Ser Gly His Leu Glu Tyr Thr Val Lys Leu Gly Asp Thr Asn Val His 
        115                 120                 125             


His Arg Ser Lys Thr Ala Leu Val Val Pro Val Arg Asp Val Val Ile 
    130                 135                 140                 


His Arg Tyr Phe Thr Ser Pro Gly Ile Ile Glu Asn Asp Ile Ala Leu 
145                 150                 155                 160 


Ala Leu Leu Asp Phe Pro Val Asn Tyr Ser Thr His Ile Gln Leu Val 
                165                 170                 175     


Cys Leu Pro Glu Gln Ala Phe Met Val Gln Ala Gly Thr Asn Cys Trp 
            180                 185                 190         


Val Thr Gly Trp Gly Lys Val Asn Glu Thr Glu Lys Ile Val Thr Glu 
        195                 200                 205             


Pro Gln Glu Ala Glu Leu Ser Ile Ile Leu His Asp Lys Cys Asn Glu 
    210                 215                 220                 


Val Leu Lys Glu Lys Ile Arg Met Arg Ser Glu Met Val Lys Lys Gly 
225                 230                 235                 240 


Thr Ile Cys Gly Tyr Asn Asp Gln Gly Lys Asp Ala Cys Gln Gly Asp 
                245                 250                 255     


Ser Gly Gly Pro Leu Val Cys Glu Leu Asn Gly Thr Trp Val Gln Val 
            260                 265                 270         


Gly Ile Val Ser Trp Gly Ile Gly Cys Gly Arg Lys Gly Tyr Pro Gly 
        275                 280                 285             


Val Tyr Thr Glu Val Ser Phe Tyr Lys Lys Trp Ile Ile Asp His Leu 
    290                 295                 300                 


Arg Gln Ala Ser Cys Leu Asn Ser Lys Thr Ser Ser Ser 
305                 310                 315         


<210>  1650
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  1650

Phe Leu Ala Leu Ala Gln Leu Leu Thr Ser Lys Asn Leu Pro Asp Thr 
1               5                   10                  15      


Val Asp Gly Gln Leu Pro Met Gly Pro His Ser Arg Ala Ser Gln Val 
            20                  25                  30          


Ala Pro Glu Thr Thr Ser Ser Lys Val Asp Arg Gly Val Ser Thr Val 
        35                  40                  45              


Cys Gly Lys Pro Lys Val Val Gly Lys Ile Tyr Gly Gly Arg Asp Ala 
    50                  55                  60                  


Ala Ala Gly Gln Trp Pro Trp Gln Ala Ser Leu Leu Tyr Trp Gly Ser 
65                  70                  75                  80  


His Leu Cys Gly Ala Val Leu Ile Asp Ser Cys Trp Leu Val Ser Thr 
                85                  90                  95      


Thr His Cys Phe Leu Asn Lys Ser Gln Ala Pro Lys Asn Tyr Gln Val 
            100                 105                 110         


Leu Leu Gly Asn Ile Gln Leu Tyr His Gln Thr Gln His Thr Gln Lys 
        115                 120                 125             


Met Ser Val His Arg Ile Ile Thr His Pro Asp Phe Glu Lys Leu His 
    130                 135                 140                 


Pro Phe Gly Ser Asp Ile Ala Met Leu Gln Leu His Leu Pro Met Asn 
145                 150                 155                 160 


Phe Thr Ser Tyr Ile Val Pro Val Cys Leu Pro Ser Arg Asp Met Gln 
                165                 170                 175     


Leu Pro Ser Asn Val Ser Cys Trp Ile Thr Gly Trp Gly Met Leu Thr 
            180                 185                 190         


Glu Asp His Lys Arg Gly Pro Val His Thr Ala Val Pro Ser Arg Leu 
        195                 200                 205             


Gln Ala Val Cys Cys Ser Gly Cys Arg Gly Gln Arg Val Gly Ser Arg 
    210                 215                 220                 


Val Gly Arg Phe Arg Ser Met Ile Val His Ser Glu Gly Gln Leu Arg 
225                 230                 235                 240 


Ser Leu Met Pro Gly Asp Phe His Leu Gly Asp Ser Gly Gly Pro Leu 
                245                 250                 255     


Val Cys Tyr Leu Pro Ser Ala Trp Val Leu Val Gly Leu Ala Ser Trp 
            260                 265                 270         


Gly Leu Asp Cys Arg His Pro Ala Tyr Pro Ser Ile Phe Thr Arg Val 
        275                 280                 285             


Thr Tyr Phe Ile Asn Trp Ile Asp Glu Ile Met Arg Leu Thr Pro Leu 
    290                 295                 300                 


Ser Asp Pro Ala Leu Ala Pro His Thr Cys Ser Pro Pro Lys Pro Leu 
305                 310                 315                 320 


Arg Ala Ala Gly Leu Pro Gly Pro Cys Ala Ala Leu Val Leu Pro Gln 
                325                 330                 335     


Thr Trp Leu Leu Leu Pro Leu Thr Leu Arg Ala Pro Trp Gln Thr Leu 
            340                 345                 350         


<210>  1651
<211>  259
<212>  PRT
<213>  Homo Sapiens

<400>  1651

Ile Thr Gly Gly Met Glu Ala Glu Val Gly Glu Phe Pro Trp Gln Val 
1               5                   10                  15      


Ser Ile Gln Ala Arg Ser Glu Pro Phe Cys Gly Gly Ser Ile Leu Asn 
            20                  25                  30          


Lys Trp Trp Ile Leu Thr Ala Ala His Cys Leu Tyr Ser Glu Glu Leu 
        35                  40                  45              


Phe Pro Glu Glu Leu Ser Val Val Leu Gly Thr Asn Asp Leu Thr Ser 
    50                  55                  60                  


Pro Ser Met Glu Ile Lys Glu Val Ala Ser Ile Ile Leu His Lys Asp 
65                  70                  75                  80  


Phe Lys Arg Ala Asn Met Asp Asn Asp Ile Ala Leu Leu Leu Leu Ala 
                85                  90                  95      


Ser Pro Ile Lys Leu Asp Asp Leu Lys Val Pro Ile Cys Leu Pro Thr 
            100                 105                 110         


Gln Pro Gly Pro Ala Thr Trp Arg Glu Cys Trp Val Ala Gly Trp Gly 
        115                 120                 125             


Gln Thr Asn Ala Ala Asp Lys Asn Ser Val Lys Thr Asp Leu Met Lys 
    130                 135                 140                 


Ala Pro Met Val Ile Met Asp Trp Glu Glu Cys Ser Lys Met Phe Pro 
145                 150                 155                 160 


Lys Leu Thr Lys Asn Met Leu Cys Ala Gly Tyr Lys Asn Glu Ser Tyr 
                165                 170                 175     


Asp Ala Cys Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Thr Pro Glu 
            180                 185                 190         


Pro Gly Glu Lys Trp Tyr Gln Val Gly Ile Ile Ser Trp Gly Lys Ser 
        195                 200                 205             


Cys Gly Glu Lys Asn Thr Pro Gly Ile Tyr Thr Ser Leu Val Asn Tyr 
    210                 215                 220                 


Asn Leu Trp Ile Glu Lys Val Thr Gln Leu Glu Gly Arg Pro Phe Asn 
225                 230                 235                 240 


Ala Glu Lys Arg Arg Thr Ser Val Lys Gln Lys Pro Met Gly Ser Pro 
                245                 250                 255     


Val Ser Gly 
            


<210>  1652
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  1652

Phe Asn Pro Asp Tyr Thr Val Ser Ser Thr Pro Pro Tyr Leu Val Tyr 
1               5                   10                  15      


Leu Lys Ser Asp Tyr Leu Pro Cys Ala Gly Val Leu Ile His Pro Leu 
            20                  25                  30          


Trp Val Ile Thr Ala Ala His Cys Asn Leu Pro Lys Leu Arg Val Ile 
        35                  40                  45              


Leu Gly Val Thr Ile Pro Ala Asp Ser Asn Glu Lys His Leu Gln Val 
    50                  55                  60                  


Ile Gly Tyr Glu Lys Met Ile His His Pro His Phe Ser Val Thr Ser 
65                  70                  75                  80  


Ile Asp His Asp Ile Met Leu Ile Lys Leu Lys Thr Glu Ala Glu Leu 
                85                  90                  95      


Asn Asp Tyr Val Lys Leu Ala Asn Leu Pro Tyr Gln Thr Ile Ser Glu 
            100                 105                 110         


Asn Thr Met Cys Ser Val Ser Thr Trp Ser Tyr Asn Val Cys Asp Ile 
        115                 120                 125             


Tyr Lys Glu Pro Asp Ser Leu Gln Thr Val Asn Ile Ser Val Ile Ser 
    130                 135                 140                 


Lys Pro Gln Cys Arg Asp Ala Tyr Lys Thr Tyr Asn Ile Thr Glu Asn 
145                 150                 155                 160 


Met Leu Cys Val Gly Ile Val Pro Gly Arg Arg Gln Pro Cys Lys Glu 
                165                 170                 175     


Val Ser Ala Ala Pro Ala Ile Cys Asn Gly Met Leu Gln Gly Ile Leu 
            180                 185                 190         


Ser Phe Ala Asp Gly Cys Val Leu Arg Ala Asp Val Gly Ile Tyr Ala 
        195                 200                 205             


Lys Ile Phe Tyr Tyr Ile Pro Trp Ile Glu Asn Val Ile Gln Asn Asn 
    210                 215                 220                 


<210>  1653
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  1653

Ser Leu Pro Cys Asp Val Cys Gln Asp Ile Ala Ala Ala Ala Gly Asn 
1               5                   10                  15      


Gly Leu Asn Pro Asp Ala Thr Glu Ser Asp Ile Leu Ala Leu Val Met 
            20                  25                  30          


Lys Thr Cys Glu Trp Leu Pro Ser Gln Glu Ser Ser Ala Gly Cys Lys 
        35                  40                  45              


Trp Met Val Asp Ala His Ser Ser Ala Ile Leu Ser Met Leu Arg Gly 
    50                  55                  60                  


Ala Pro Asp Ser Ala Pro Ala Gln Val Cys Thr Ala Leu Ser Leu Cys 
65                  70                  75                  80  


Glu Pro Leu Gln 
                


<210>  1654
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  1654

Ser Glu Gly His Pro Ser His Pro Pro Ala Glu Asp Arg Glu Glu Ala 
1               5                   10                  15      


Gly Ser Pro Thr Leu Pro Gln Gly Pro Pro Val Pro Gly Asp Pro Trp 
            20                  25                  30          


Pro Gly Ala Pro Pro Leu Phe Glu Asp Pro Pro Pro Thr Arg Pro Ser 
        35                  40                  45              


Arg Pro Trp Arg Asp Leu Pro Glu Thr Gly Val Trp Leu Pro Glu Pro 
    50                  55                  60                  


Pro Arg Thr Asp Pro Pro Gln Pro Pro Arg Pro Asp Asp Pro Trp Pro 
65                  70                  75                  80  


Ala Gly Pro Gln Pro Pro Glu Asn Pro Trp Pro Pro Ala Pro Glu Val 
                85                  90                  95      


Asp Asn Arg Pro Gln Glu Glu Pro Asp Leu Asp Pro Pro Arg Glu Glu 
            100                 105                 110         


Tyr Arg 
        


<210>  1655
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  1655

Ser Val Ser Glu Ile Gln Leu Met His Asn Leu Gly Lys His Leu Asn 
1               5                   10                  15      


Ser Met Glu Arg Val Glu Trp Leu Arg Lys Lys Leu Gln Asp Val His 
            20                  25                  30          


Asn Phe Val Ala Leu Gly Ala Pro Leu Ala Pro Arg Asp Ala Gly Ser 
        35                  40                  45              


Gln Arg Pro Arg Lys Lys Glu Asp Asn Val Leu Val Glu Ser His Glu 
    50                  55                  60                  


Lys Ser Leu Gly Glu Ala Asp Lys Ala Asp Val Asn Val Leu Thr Lys 
65                  70                  75                  80  


Ala Lys Ser Gln 
                


<210>  1656
<211>  453
<212>  PRT
<213>  Homo Sapiens

<400>  1656

Gln Glu Ala Ala Pro Val Gly Pro Arg Lys Pro Phe Phe Glu Arg Leu 
1               5                   10                  15      


Arg Arg Leu Glu Glu Gln Phe Arg Arg Phe Gln Glu Val Thr Trp Thr 
            20                  25                  30          


His Leu Gln Asn Ile Ala Ser Asn Tyr Asn Val Ser Tyr Asn Val Asp 
        35                  40                  45              


Val Arg Phe Arg Ser Leu Ala Glu Glu Ser Gln Ala Val Ala Gln Ala 
    50                  55                  60                  


Val Asn Arg Ser Gln Ala Ser Val Gln Gly Glu Leu Ala Gln Leu Lys 
65                  70                  75                  80  


Ala Trp Val Arg Lys Leu Gln Arg Arg Gly Arg Lys Val Asp Thr Arg 
                85                  90                  95      


Leu Arg Ala Leu Asp Leu Thr Leu Gly Glu Arg Ser Gln Gln Arg Ala 
            100                 105                 110         


Arg Glu Arg Lys Ala His Lys Ala Gln Arg Asp Ala Leu Gln Asp Ser 
        115                 120                 125             


Leu Ala Arg Leu Glu Gly Leu Val His Ser Gln Gly Ala Arg Leu Ala 
    130                 135                 140                 


Ala Leu Glu Gly Arg Leu Pro Val Ala His Pro Gly Thr Ala Ala Leu 
145                 150                 155                 160 


Gly Pro Ala Leu Val Pro Thr Pro Thr Gln Pro Glu Glu Leu Gly Pro 
                165                 170                 175     


Thr Ser Leu Lys Leu Gln Arg Asp Arg Gln Glu Leu Arg Ala Ala Ser 
            180                 185                 190         


Glu His Arg Gly Pro Pro Gln Asp Ser Ser Ala Pro Leu Gln Gly Arg 
        195                 200                 205             


Arg Glu Pro Pro Ala Ser Gly Ser His Arg Val Leu Ser Gly Thr Ala 
    210                 215                 220                 


Pro Lys Asp Pro Arg Gln Gln Ala Trp Ser Pro Gln Val Pro Gly Glu 
225                 230                 235                 240 


Ile Cys Gly Val Gly Pro Thr Leu Val Phe Pro Asn Ala Ser Thr Arg 
                245                 250                 255     


Asn Val Val Phe Leu Ser Pro Gly Phe Val Thr Ala Leu Arg Ala Leu 
            260                 265                 270         


Ser Phe Cys Ser Trp Val Arg Thr Ala Ser Gly Arg Leu Gly Thr Leu 
        275                 280                 285             


Leu Ser Tyr Ala Thr Glu Asp Asn Asp Asn Lys Leu Val Leu His Gly 
    290                 295                 300                 


Arg Asp Ser Leu Leu Pro Gly Ser Ile His Phe Val Ile Gly Asp Pro 
305                 310                 315                 320 


Ala Phe Arg Glu Leu Pro Leu Gln Leu Leu Leu Asp Gly Gln Trp His 
                325                 330                 335     


His Ile Cys Val Ile Trp Thr Ser Thr Gln Gly Arg Tyr Trp Leu His 
            340                 345                 350         


Val Asp Arg Arg Leu Val Ala Thr Gly Ser Arg Phe Arg Glu Gly Tyr 
        355                 360                 365             


Glu Ile Pro Pro Gly Gly Ser Leu Val Leu Gly Gln Glu Gln Asp Ser 
    370                 375                 380                 


Val Gly Gly Gly Phe Asp Ser Ser Glu Ala Phe Val Gly Ser Met Ser 
385                 390                 395                 400 


Gly Leu Ala Ile Trp Asp Arg Ala Leu Val Pro Gly Glu Val Ala Asn 
                405                 410                 415     


Leu Ala Ile Gly Lys Glu Phe Pro Thr Gly Ala Ile Leu Thr Leu Ala 
            420                 425                 430         


Asn Ala Ala Leu Ala Gly Gly Phe Val Gln Gly Ala Asn Cys Thr Cys 
        435                 440                 445             


Leu Glu Arg Cys Pro 
    450             


<210>  1657
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  1657

Gly Leu Ala Asp Pro His Ser Leu Cys Tyr Asp Ile Thr Val Ile Pro 
1               5                   10                  15      


Lys Phe Arg Pro Gly Pro Arg Trp Cys Ala Val Gln Gly Gln Val Asp 
            20                  25                  30          


Glu Lys Thr Phe Leu His Tyr Asp Cys Gly Ser Lys Thr Val Thr Pro 
        35                  40                  45              


Val Ser Pro Leu Gly Lys Lys Leu Asn Val Thr Thr Ala Trp Lys Ala 
    50                  55                  60                  


Gln Asn Pro Val Leu Arg Glu Val Val Asp Ile Leu Thr Glu Gln Leu 
65                  70                  75                  80  


Leu Asp Ile Gln Leu Glu Asn Tyr Ile Pro Lys Glu Pro Leu Thr Leu 
                85                  90                  95      


Gln Ala Arg Met Ser Cys Glu Gln Lys Ala Glu Gly His Gly Ser Gly 
            100                 105                 110         


Ser Trp Gln Leu Ser Phe Asp Gly Gln Ile Phe Leu Leu Phe Asp Ser 
        115                 120                 125             


Glu Asn Arg Met Trp Thr Thr Val His Pro Gly Ala Arg Lys Met Lys 
    130                 135                 140                 


Glu Lys Trp Glu Asn Asp Lys Asp Met Thr Met Ser Phe His Tyr Ile 
145                 150                 155                 160 


Ser Met Gly Asp Cys Thr Gly Trp Leu Glu Asp Phe Leu Met Gly Met 
                165                 170                 175     


Asp Ser Thr Leu Glu Pro Ser Ala Gly Ala Pro Pro Thr Met Ser Ser 
            180                 185                 190         


Gly 
    


<210>  1658
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  1658

Arg Arg Asp Asp Pro His Ser Leu Cys Tyr Asp Ile Thr Val Ile Pro 
1               5                   10                  15      


Lys Phe Arg Pro Gly Pro Arg Trp Cys Ala Val Gln Gly Gln Val Asp 
            20                  25                  30          


Glu Lys Thr Phe Leu His Tyr Asp Cys Gly Asn Lys Thr Val Thr Pro 
        35                  40                  45              


Val Ser Pro Leu Gly Lys Lys Leu Asn Val Thr Met Ala Trp Lys Ala 
    50                  55                  60                  


Gln Asn Pro Val Leu Arg Glu Val Val Asp Ile Leu Thr Glu Gln Leu 
65                  70                  75                  80  


Leu Asp Ile Gln Leu Glu Asn Tyr Thr Pro Lys Glu Pro Leu Thr Leu 
                85                  90                  95      


Gln Ala Arg Met Ser Cys Glu Gln Lys Ala Glu Gly His Ser Ser Gly 
            100                 105                 110         


Ser Trp Gln Phe Ser Ile Asp Gly Gln Thr Phe Leu Leu Phe Asp Ser 
        115                 120                 125             


Glu Lys Arg Met Trp Thr Thr Val His Pro Gly Ala Arg Lys Met Lys 
    130                 135                 140                 


Glu Lys Trp Glu Asn Asp Lys Asp Val Ala Met Ser Phe His Tyr Ile 
145                 150                 155                 160 


Ser Met Gly Asp Cys Ile Gly Trp Leu Glu Asp Phe Leu Met Gly Met 
                165                 170                 175     


Asp Ser Thr Leu Glu Pro Ser Ala Gly Ala Pro Leu Ala Met Ser Ser 
            180                 185                 190         


Gly 
    


<210>  1659
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  1659

Met Ala Val Asp Val Glu Phe Gly Val Ala Gly Trp Trp Glu Ala Ala 
1               5                   10                  15      


Ala Pro Leu Ser Pro Ser Ala Val Ala Ala Thr Phe Thr Glu Thr Trp 
            20                  25                  30          


Pro Gly Ser Glu Arg Ala Glu Pro Gly Arg Ile Gln His Pro Leu Trp 
        35                  40                  45              


Pro Gly Ser Ser Glu Gly Leu Gln Leu Leu Val Cys Phe Leu Leu Leu 
    50                  55                  60                  


Asn Ser Cys Pro Gly Gly Cys Ser Asp Thr Ser Ala His Asp Gly Gln 
65                  70                  75                  80  


Asp Gln Val Gly Val Gly Gln Leu Trp Pro Leu Gln Gly Phe Ala Thr 
                85                  90                  95      


Pro Val Phe Gln His Leu Gln Val Val Leu Gln Gln Ile Ile Pro Gln 
            100                 105                 110         


Gly Leu Phe Trp Lys Asp Asp Ile Thr Gln Asp Ala Met Ile Gln Lys 
        115                 120                 125             


Met Glu His Ala Ser Arg Leu His Pro Gln Glu Pro Cys Leu Lys Asp 
    130                 135                 140                 


Gly Lys Ala Leu Phe Pro Thr Lys Thr Thr Glu Ser Pro Leu Ala Lys 
145                 150                 155                 160 


Val Asn Arg Asp Gln Cys Phe Thr Ser Glu Val Val Ser Lys Ala Leu 
                165                 170                 175     


Lys Gln Glu Val Ala Asn Pro Val Lys Ile Thr Tyr Arg Cys Ser Tyr 
            180                 185                 190         


Gly Gly Leu Asp Met Met Gln Ala Pro Gly Pro Ser Lys Glu Glu Ile 
        195                 200                 205             


Ile Tyr Lys Ile Met Arg Leu Leu Trp Ala Thr Ser Tyr Cys Gly Pro 
    210                 215                 220                 


Gln Pro Cys Gly 
225             


<210>  1660
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  1660

Asp Asn Ala Ser Gln Glu Tyr Tyr Thr Ala Leu Ile Asn Val Thr Val 
1               5                   10                  15      


Gln Glu Pro Gly Arg Gly Ala Pro Leu Thr Phe Arg Ile Asp Arg Gly 
            20                  25                  30          


Arg Tyr Gly Leu Asp Ser Pro Lys Ala Glu Val Arg Gly Gln Val Leu 
        35                  40                  45              


Ala Pro Leu Pro Leu His Gly Val Ala Asp His Leu Gly Cys Asp Pro 
    50                  55                  60                  


Gln Thr Arg Phe Phe Val Pro Pro Asn Ile Lys Gln Trp Ile Ala Leu 
65                  70                  75                  80  


Leu Gln Arg Gly Asn Cys Thr Phe Lys Glu Lys Ile Ser Arg Ala Ala 
                85                  90                  95      


Phe His Asn Ala Val Ala Val Val Ile Tyr Asn Asn Lys Ser Lys Glu 
            100                 105                 110         


Glu Pro Val Thr Met Thr His Pro Gly Thr Gly Asp Ile Ile Ala Val 
        115                 120                 125             


Met Ile Thr Glu Leu Arg Gly Lys Asp Ile Leu Ser Tyr Leu Glu Lys 
    130                 135                 140                 


Asn Ile Ser Val Gln Met Thr Ile Ala Val Gly Thr Arg Met Pro Pro 
145                 150                 155                 160 


Lys Asn Phe Ser Arg Gly Ser 
                165         


<210>  1661
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  1661

Lys Ala Ile Trp Thr Ala His Leu Asn Ile Thr Phe Gln Val Gly Asn 
1               5                   10                  15      


Glu Ile Thr Ser Glu Leu Gly Glu Ser Gly Val Phe Gly Asn His Ser 
            20                  25                  30          


Pro Leu Glu Arg Val Ser Gly Val Val Ala Leu Pro Glu Gly Trp Asn 
        35                  40                  45              


Gln Asn Ala Cys His Pro Leu Thr Asn Phe Ser Arg Pro Lys Gln Ala 
    50                  55                  60                  


Asp Ser Trp Leu Ala Leu Ile Glu Arg Gly Gly Cys Thr Phe Thr His 
65                  70                  75                  80  


Lys Ile Asn Val Ala Ala Glu Lys Gly Ala Asn Gly Val Ile Ile Tyr 
                85                  90                  95      


Asn Tyr Gln Gly Thr Gly Ser Lys Val Phe Pro Met Ser His Gln Gly 
            100                 105                 110         


Thr Glu Asn Ile Val Ala Val Met Ile Ser Asn Leu Lys Gly Met Glu 
        115                 120                 125             


Ile Leu His Ser Ile Gln Lys Gly Val Tyr Val Thr Val Ile Ile Glu 
    130                 135                 140                 


Val Gly Arg Met His Met 
145                 150 


<210>  1662
<211>  149
<212>  PRT
<213>  Homo Sapiens

<400>  1662

Leu Ile Arg Ala Thr Ser Asp His Asn Ala Ser Met Asp Phe Ala Asp 
1               5                   10                  15      


Leu Pro Ala Leu Phe Gly Ala Thr Leu Ser Gln Glu Gly Leu Gln Gly 
            20                  25                  30          


Phe Leu Val Glu Ala His Pro Asp Asn Ala Cys Ser Pro Ile Ala Pro 
        35                  40                  45              


Pro Pro Pro Ala Pro Val Asn Gly Ser Val Phe Ile Ala Leu Leu Arg 
    50                  55                  60                  


Arg Phe Asp Cys Asn Phe Asp Leu Lys Val Leu Asn Ala Gln Lys Ala 
65                  70                  75                  80  


Gly Tyr Gly Ala Ala Val Val His Asn Val Asn Ser Asn Glu Leu Leu 
                85                  90                  95      


Asn Met Val Trp Asn Ser Glu Glu Ile Gln Gln Gln Ile Trp Ile Pro 
            100                 105                 110         


Ser Val Phe Ile Gly Glu Arg Ser Ser Glu Tyr Leu Arg Ala Leu Phe 
        115                 120                 125             


Val Tyr Glu Lys Gly Ala Arg Val Leu Leu Val Pro Asp Asn Thr Phe 
    130                 135                 140                 


Pro Leu Gly Tyr Tyr 
145                 


<210>  1663
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  1663

Met Trp Leu Phe Thr Val Asn Gln Val Leu Arg Lys Met Gln Arg Arg 
1               5                   10                  15      


His Ser Ser Asn Thr Asp Asn Ile Pro Pro Glu Arg Asn Arg Ser Gln 
            20                  25                  30          


Ala Leu Ser Ser Glu Ala Ser Val Asp Glu Gly Gly Val Phe Glu Ser 
        35                  40                  45              


Leu Lys Ala Glu Ala Ala Ser Pro Pro Ala Leu Phe Ser Gly Leu Ser 
    50                  55                  60                  


Gly Ser Leu Pro Thr Ser Ser Phe Pro Ser Ser Leu Val Leu Gly Ser 
65                  70                  75                  80  


Ser Ala Gly Gly Gly Asp Val Phe Ile Gln Met Pro Ala Ser Arg Glu 
                85                  90                  95      


Glu Gly Gly Gly Arg Gly Glu Gly Gly Ala Tyr His His Arg Gln Pro 
            100                 105                 110         


His His His Phe His His Gly Gly His Arg Gly Gly Ser Leu Leu Gln 
        115                 120                 125             


His Val Gly Gly Asp His Arg Gly His Ser Glu Glu Gly Gly Asp Glu 
    130                 135                 140                 


Gln Pro Gly Thr Pro Ala Pro Ala Leu Ser Glu Leu Lys Ala Val Ile 
145                 150                 155                 160 


Cys Trp Leu Gln Lys Gly Leu Pro Phe Ile Leu Ile Leu Leu Ala Lys 
                165                 170                 175     


Leu Cys Phe Gln His 
            180     


<210>  1664
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  1664

Gln Gly Asn Arg Trp Arg Arg Ser Lys Arg Ala Ser Tyr Val Ser Asn 
1               5                   10                  15      


Pro Ile Cys Lys Gly Cys Leu Ser Cys Ser Lys Asp Asn Gly Cys Ser 
            20                  25                  30          


Arg Cys Gln Gln Lys Leu Phe Phe Phe Leu Arg Arg Glu Gly Met Arg 
        35                  40                  45              


Gln Tyr Gly Glu Cys Leu His Ser Cys Pro Ser Gly Tyr Tyr Gly His 
    50                  55                  60                  


Arg Ala Pro Asp Met Asn Arg Cys Ala Arg Cys Arg Ile Glu Asn Cys 
65                  70                  75                  80  


Asp Ser Cys Phe Ser Lys Asp Phe Cys Thr Lys Cys Lys Val Gly Phe 
                85                  90                  95      


Tyr Leu His Arg Gly Arg Cys Phe Asp Glu Cys Pro Asp Gly Phe Ala 
            100                 105                 110         


Pro Leu Glu Glu Thr Met Glu Cys Val Glu Gly Cys Glu Val Gly His 
        115                 120                 125             


Trp Ser Glu Trp Gly Thr Cys Ser Arg Asn Asn Arg Thr Cys Gly Phe 
    130                 135                 140                 


Lys Trp Gly Leu Glu Thr Arg Thr Arg Gln Ile Val Lys Lys Pro Val 
145                 150                 155                 160 


Lys Asp Thr Ile Leu Cys Pro Thr Ile Ala Glu Ser Arg Arg Cys Lys 
                165                 170                 175     


Met Thr Met Arg His Cys Pro Gly Gly Lys Arg Thr Pro Lys Ala Lys 
            180                 185                 190         


Glu Lys Arg Asn Lys Lys Lys Lys Arg Lys Leu Ile Glu Arg Ala Gln 
        195                 200                 205             


Glu Gln His Ser Val Phe Leu Ala Thr Asp Arg Ala Asn Gln 
    210                 215                 220         


<210>  1665
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  1665

Thr Lys Leu Glu Glu His Leu Glu Gly Ile Val Asn Ile Phe His Gln 
1               5                   10                  15      


Tyr Ser Val Arg Lys Gly His Phe Asp Thr Leu Ser Lys Gly Glu Leu 
            20                  25                  30          


Lys Gln Leu Leu Thr Lys Glu Leu Ala Asn Thr Ile Lys Asn Ile Lys 
        35                  40                  45              


Asp Lys Ala Val Ile Asp Glu Ile Phe Gln Gly Leu Asp Ala Asn Gln 
    50                  55                  60                  


Asp Glu Gln Val Asp Phe Gln Glu Phe Ile Ser Leu Val Ala Ile Ala 
65                  70                  75                  80  


Leu Lys Ala Ala His Tyr His Thr His Lys Glu 
                85                  90      


<210>  1666
<211>  414
<212>  PRT
<213>  Homo Sapiens

<400>  1666

Ser Arg Pro Arg Ser Ser Pro Asp Asp Leu Lys Ala Leu Thr Arg Asn 
1               5                   10                  15      


Val Asn Arg Leu Asn Glu Ser Phe Arg Asp Leu Gln Leu Arg Leu Leu 
            20                  25                  30          


Gln Ala Pro Leu Gln Ala Asp Leu Thr Glu Gln Val Trp Lys Val Gln 
        35                  40                  45              


Asp Ala Leu Gln Asn Gln Ser Asp Ser Leu Leu Ala Leu Ala Gly Ala 
    50                  55                  60                  


Val Gln Arg Leu Glu Gly Ala Leu Trp Gly Leu Gln Ala Gln Ala Val 
65                  70                  75                  80  


Gln Thr Glu Gln Ala Val Ala Leu Leu Arg Asp Arg Thr Gly Gln Gln 
                85                  90                  95      


Ser Asp Thr Ala Gln Leu Glu Leu Tyr Gln Leu Gln Val Glu Ser Asn 
            100                 105                 110         


Ser Ser Gln Leu Leu Leu Arg Arg His Ala Gly Leu Leu Asp Gly Leu 
        115                 120                 125             


Ala Arg Arg Val Gly Ile Leu Gly Glu Glu Leu Ala Asp Val Gly Gly 
    130                 135                 140                 


Val Leu Arg Gly Leu Asn His Ser Leu Ser Tyr Asp Val Ala Leu His 
145                 150                 155                 160 


Arg Thr Arg Leu Gln Asp Leu Arg Val Leu Val Ser Asn Ala Ser Glu 
                165                 170                 175     


Asp Thr Arg Arg Leu Arg Leu Ala His Val Gly Met Glu Leu Gln Leu 
            180                 185                 190         


Lys Gln Glu Leu Ala Met Leu Asn Ala Val Thr Glu Asp Leu Arg Leu 
        195                 200                 205             


Lys Asp Trp Glu His Ser Ile Ala Leu Arg Asn Ile Ser Leu Ala Lys 
    210                 215                 220                 


Gly Pro Pro Gly Pro Lys Gly Asp Gln Gly Asp Glu Gly Lys Glu Gly 
225                 230                 235                 240 


Arg Pro Gly Ile Pro Gly Leu Pro Gly Leu Arg Gly Leu Pro Gly Glu 
                245                 250                 255     


Arg Gly Thr Pro Gly Leu Pro Gly Pro Lys Gly Asp Asp Gly Lys Leu 
            260                 265                 270         


Gly Ala Thr Gly Pro Met Gly Met Arg Gly Phe Lys Gly Asp Arg Gly 
        275                 280                 285             


Pro Lys Gly Glu Lys Gly Glu Lys Gly Asp Arg Ala Gly Asp Ala Ser 
    290                 295                 300                 


Gly Val Glu Ala Pro Met Met Ile Arg Leu Val Asn Gly Ser Gly Pro 
305                 310                 315                 320 


His Glu Gly Arg Val Glu Val Tyr His Asp Arg Arg Trp Gly Thr Val 
                325                 330                 335     


Cys Asp Asp Gly Trp Asp Lys Lys Asp Gly Asp Val Val Cys Arg Met 
            340                 345                 350         


Leu Gly Phe Arg Gly Val Glu Glu Val Tyr Arg Thr Ala Arg Phe Gly 
        355                 360                 365             


Gln Gly Thr Gly Arg Ile Trp Met Asp Asp Val Ala Cys Lys Gly Thr 
    370                 375                 380                 


Glu Glu Thr Ile Phe Arg Cys Ser Phe Ser Lys Trp Gly Val Thr Asn 
385                 390                 395                 400 


Cys Gly His Ala Glu Asp Ala Ser Val Thr Cys Asn Arg His 
                405                 410                 


<210>  1667
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  1667

Glu Asp Asn Asp Glu Phe Phe Met Asp Phe Leu Gln Thr Leu Leu Val 
1               5                   10                  15      


Gly Thr Pro Glu Glu Leu Tyr Glu Gly Thr Leu Gly Lys Tyr Asn Val 
            20                  25                  30          


Asn Glu Asp Ala Lys Ala Ala Met Thr Glu Leu Lys Ser Cys Ile Asp 
        35                  40                  45              


Gly Leu Gln Pro Met His Lys Ala Glu Leu Val Lys Leu Leu Val Gln 
    50                  55                  60                  


Val Leu Gly Ser Gln Asp Gly Ala 
65                  70          


<210>  1668
<211>  387
<212>  PRT
<213>  Homo Sapiens

<400>  1668

Met Lys Pro Gly Pro Pro His Arg Ala Gly Ala Ala His Gly Ala Gly 
1               5                   10                  15      


Ala Gly Ala Gly Ala Ala Ala Gly Pro Gly Ala Arg Gly Leu Leu Leu 
            20                  25                  30          


Pro Pro Leu Leu Leu Leu Leu Leu Ala Gly Arg Ala Ala Gly Ala Gln 
        35                  40                  45              


Arg Trp Arg Ser Glu Asn Phe Glu Arg Pro Val Asp Leu Glu Gly Ser 
    50                  55                  60                  


Gly Asp Asp Asp Ser Phe Pro Asp Asp Glu Leu Asp Asp Leu Tyr Ser 
65                  70                  75                  80  


Gly Ser Gly Ser Gly Tyr Phe Glu Gln Glu Ser Gly Ile Glu Thr Ala 
                85                  90                  95      


Met Arg Phe Ser Pro Asp Val Ala Leu Ala Val Ser Thr Thr Pro Ala 
            100                 105                 110         


Val Leu Pro Thr Thr Asn Ile Gln Pro Val Gly Thr Pro Phe Glu Glu 
        115                 120                 125             


Leu Pro Ser Glu Arg Pro Thr Leu Glu Pro Ala Thr Ser Pro Leu Val 
    130                 135                 140                 


Val Thr Glu Val Pro Glu Glu Pro Ser Gln Arg Ala Thr Thr Val Ser 
145                 150                 155                 160 


Thr Thr Met Ala Thr Thr Ala Ala Thr Ser Thr Gly Asp Pro Thr Val 
                165                 170                 175     


Ala Thr Val Pro Ala Thr Val Ala Thr Ala Thr Pro Ser Thr Pro Ala 
            180                 185                 190         


Ala Pro Pro Phe Thr Ala Thr Thr Ala Val Ile Arg Thr Thr Gly Val 
        195                 200                 205             


Arg Arg Leu Leu Pro Leu Pro Leu Thr Thr Val Ala Thr Ala Arg Ala 
    210                 215                 220                 


Thr Thr Pro Glu Ala Pro Ser Pro Pro Thr Thr Ala Ala Val Leu Asp 
225                 230                 235                 240 


Thr Glu Ala Pro Thr Pro Arg Leu Val Ser Thr Ala Thr Ser Arg Pro 
                245                 250                 255     


Arg Ala Leu Pro Arg Pro Ala Thr Thr Gln Glu Pro Asp Ile Pro Glu 
            260                 265                 270         


Arg Ser Thr Leu Pro Leu Gly Thr Thr Ala Pro Gly Pro Thr Glu Val 
        275                 280                 285             


Ala Gln Thr Pro Thr Pro Glu Thr Phe Leu Thr Thr Ile Arg Asp Glu 
    290                 295                 300                 


Pro Glu Val Pro Val Ser Gly Gly Pro Ser Gly Asp Phe Glu Leu Pro 
305                 310                 315                 320 


Glu Glu Glu Thr Thr Gln Pro Asp Thr Ala Asn Glu Val Val Ala Val 
                325                 330                 335     


Gly Gly Ala Ala Ala Lys Ala Ser Ser Pro Pro Gly Thr Leu Pro Lys 
            340                 345                 350         


Gly Ala Arg Pro Gly Pro Gly Leu Leu Asp Asn Ala Ile Asp Ser Gly 
        355                 360                 365             


Ser Ser Ala Ala Gln Leu Pro Gln Lys Ser Ile Leu Glu Arg Lys Glu 
    370                 375                 380                 


Val Leu Val 
385         


<210>  1669
<211>  142
<212>  PRT
<213>  Homo Sapiens

<400>  1669

Lys Gly Leu Met Val Ile Thr Gly Ser Glu Ser Pro Ile Val Leu Leu 
1               5                   10                  15      


Ser Gly Ser Met Glu Pro Ala Phe His Arg Gly Tyr Leu Leu Phe Leu 
            20                  25                  30          


Thr Asn Arg Val Glu Asp Pro Ile Arg Val Gly Glu Ile Ala Val Leu 
        35                  40                  45              


Arg Ile Glu Gly Arg Lys Ile Pro Ile Val His Arg Val Leu Lys Ile 
    50                  55                  60                  


His Glu Lys Gln Asn Gly His Ile Lys Phe Leu Thr Lys Gly Asp Asn 
65                  70                  75                  80  


Asn Ala Val Asp Asp Arg Gly Leu Tyr Lys Gln Asp Gln His Trp Leu 
                85                  90                  95      


Glu Lys Lys Asp Val Val Gly Arg Ala Arg Gly Phe Val Pro Tyr Ile 
            100                 105                 110         


Gly Ile Gly Thr Ser Leu Met Asn Asp Tyr Pro Lys His Lys Tyr Glu 
        115                 120                 125             


Val Leu Phe Leu Leu Gly Leu Phe Val Leu Val His Arg Glu 
    130                 135                 140         


<210>  1670
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  1670

Gln Lys Gly Gly Ser Lys Gly Arg Leu Pro Ser Glu Phe Ser Gln Phe 
1               5                   10                  15      


Pro His Gly Gln Lys Gly Gln His Tyr Ser Gly Gln Lys Gly Lys Gln 
            20                  25                  30          


Gln Thr Glu Ser Lys Gly Ser Phe Ser Ile Gln Tyr Thr Tyr His Val 
        35                  40                  45              


Asp Ala Asn Asp His Asp Gln Ser Arg Lys Ser Gln Gln Tyr Asp Leu 
    50                  55                  60                  


Asn Ala Leu His Lys Thr Thr Lys Ser Gln Arg His Leu Gly Gly Ser 
65                  70                  75                  80  


Gln Gln Leu Leu His Asn Lys Gln Glu Gly Arg Asp His Asp Lys Ser 
                85                  90                  95      


Lys Gly His Phe His Arg Val Val Ile His His Lys Gly Gly Lys Ala 
            100                 105                 110         


His Arg Gly Thr Gln Asn Pro Ser Gln Asp Gln Gly Asn Ser Pro Ser 
        115                 120                 125             


Gly Lys Gly Ile Ser Ser Gln Tyr Ser Asn Thr Glu Glu Arg Leu Trp 
    130                 135                 140                 


Val His Gly Leu Ser Lys Glu Gln Thr Ser Val Ser Gly Ala Gln Lys 
145                 150                 155                 160 


Gly Arg Lys Gln Gly Gly Ser Gln Ser Ser Tyr Val Leu Gln Thr Glu 
                165                 170                 175     


Glu Leu Val Ala Asn Lys Gln Gln Arg Glu Thr Lys Asn Ser His Gln 
            180                 185                 190         


Asn Lys Gly His Tyr Gln Asn Val Val Glu Val Arg Glu Glu His Ser 
        195                 200                 205             


Ser Lys Val Gln Thr Ser Leu Cys Pro Ala His Gln Asp Lys Leu Gln 
    210                 215                 220                 


His Gly Ser Lys Asp Ile Phe Ser Thr Gln Asp Glu Leu Leu Val Tyr 
225                 230                 235                 240 


Asn Lys Asn Gln His Gln Thr Lys Asn Leu Asn Gln Asp Gln Gln His 
                245                 250                 255     


Gly Arg Lys Ala Asn Lys Ile Ser Tyr Gln Ser Ser Ser Thr Glu Glu 
            260                 265                 270         


Arg Arg Leu His Tyr Gly Glu Asn Gly Val Gln Lys Asp Val Ser Gln 
        275                 280                 285             


Ser Ser Ile Tyr Ser Gln Thr Glu Glu Lys Ala Gln Gly Lys Ser Gln 
    290                 295                 300                 


Lys Gln Ile Thr Ile Pro Ser Gln Glu Gln Glu His Ser Gln Lys Ala 
305                 310                 315                 320 


Asn Lys Ile Ser Tyr Gln Ser Ser Ser Thr Glu Glu Arg Arg Leu His 
                325                 330                 335     


Tyr Gly Glu Asn Gly Val Gln Lys Asp Val Ser Gln Arg Ser Ile Tyr 
            340                 345                 350         


Ser Gln Thr Glu Lys Leu Val Ala Gly Lys Ser Gln Ile Gln Ala Pro 
        355                 360                 365             


Asn Pro Lys Gln Glu Pro Trp His Gly Glu Asn Ala Lys Gly Glu Ser 
    370                 375                 380                 


Gly Gln Ser Thr Asn Arg Glu Gln Asp Leu Leu Ser His Glu Gln Lys 
385                 390                 395                 400 


Gly Arg His Gln His Gly Ser His Gly Gly Leu Asp Ile Val Ile Ile 
                405                 410                 415     


Glu Gln Glu Asp Asp Ser Asp Arg His Leu Ala Gln His Leu Asn Asn 
            420                 425                 430         


Asp Arg Asn Pro Leu Phe Thr 
        435                 


<210>  1671
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  1671

Leu Val Asp Gln Glu Ala Ser Asp Leu Ile His Ser Gly Pro Gln Asp 
1               5                   10                  15      


Ser Ser Pro Gly Pro Ala Leu Pro Cys His Lys Ile Ser Val Ser Asn 
            20                  25                  30          


Ile Asp Phe Ala Phe Lys Leu Tyr Arg Gln Leu Ala Leu Asn Ala Pro 
        35                  40                  45              


Gly Glu Asn Ile Leu Phe Phe Pro Val Ser Ile Ser Leu Ala Leu Ala 
    50                  55                  60                  


Met Leu Ser Trp Gly Ala Pro Val Ala Ser Arg Thr Gln Leu Leu Glu 
65                  70                  75                  80  


Gly Leu Gly Phe Thr Leu Thr Val Val Pro Glu Glu Glu Ile Gln Glu 
                85                  90                  95      


Gly Phe Trp Asp Leu Leu Ile Arg Leu Arg Gly Gln Gly Pro Arg Leu 
            100                 105                 110         


Leu Leu Thr Met Asp Gln Arg Arg Phe Ser Gly Leu Gly Ala Arg Ala 
        115                 120                 125             


Asn Gln Ser Leu Glu Glu Ala Gln Lys His Ile Asp Glu Tyr Thr Glu 
    130                 135                 140                 


Gln Gln Thr Gln Gly Lys Leu Gly Ala Trp Glu Lys Asp Leu Gly Ser 
145                 150                 155                 160 


Glu Thr Thr Ala Val Leu Val Asn His Met Leu Leu Arg Ala Glu Trp 
                165                 170                 175     


Met Lys Pro Phe Asp Ser His Ala Thr Ser Pro Lys Glu Phe Phe Val 
            180                 185                 190         


Asp Glu His Ser Ala Val Trp Val Pro Met Met Lys Glu Lys Ala Ser 
        195                 200                 205             


His Arg Phe Leu His Asp Arg Glu Leu Gln Cys Ser Val Leu Arg Met 
    210                 215                 220                 


Asp His Ala Gly Asn Thr Thr Thr Phe Phe Ile Phe Pro Asn Arg Gly 
225                 230                 235                 240 


Lys Met Arg His Leu Glu Asp Ala Leu Leu Pro Glu Thr Leu Ile Lys 
                245                 250                 255     


Trp Asp Ser Leu Leu Arg Thr Arg Glu Leu Asp Phe His Phe Pro Lys 
            260                 265                 270         


Phe Ser Ile Ser Arg Thr Cys Arg Leu Glu Met Leu Leu Pro 
        275                 280                 285     


<210>  1672
<211>  399
<212>  PRT
<213>  Homo Sapiens

<400>  1672

Ser Leu Val Glu Asp Pro Gln Gly Asp Ala Ala Gln Lys Thr Asp Thr 
1               5                   10                  15      


Ser His His Asp Gln Gly Asp Trp Glu Asp Leu Ala Cys Gln Lys Ile 
            20                  25                  30          


Ser Tyr Asn Val Thr Asp Leu Ala Phe Asp Leu Tyr Lys Ser Trp Leu 
        35                  40                  45              


Ile Tyr His Asn Gln His Val Leu Val Thr Pro Thr Ser Val Ala Met 
    50                  55                  60                  


Ala Phe Arg Met Leu Ser Leu Gly Thr Lys Ala Asp Thr Arg Thr Glu 
65                  70                  75                  80  


Ile Leu Glu Gly Leu Asn Val Asn Leu Thr Glu Thr Pro Glu Ala Lys 
                85                  90                  95      


Ile His Glu Cys Phe Gln Gln Val Leu Gln Ala Leu Ser Arg Pro Asp 
            100                 105                 110         


Thr Arg Leu Gln Leu Thr Thr Gly Ser Ser Leu Phe Val Asn Lys Ser 
        115                 120                 125             


Met Lys Leu Val Asp Thr Phe Leu Glu Asp Thr Lys Lys Leu Tyr His 
    130                 135                 140                 


Ser Glu Ala Ser Ser Ile Asn Phe Arg Asp Thr Glu Glu Ala Lys Glu 
145                 150                 155                 160 


Gln Ile Asn Asn Tyr Val Glu Lys Arg Thr Gly Arg Lys Val Val Asp 
                165                 170                 175     


Leu Val Lys His Leu Lys Lys Asp Thr Ser Leu Ala Leu Val Asp Tyr 
            180                 185                 190         


Ile Ser Phe His Gly Lys Trp Lys Asp Lys Phe Lys Ala Glu Arg Ile 
        195                 200                 205             


Met Val Glu Gly Phe His Val Asp Asp Lys Thr Ile Ile Arg Val Pro 
    210                 215                 220                 


Met Ile Asn His Leu Gly Arg Phe Asp Ile His Arg Asp Arg Glu Leu 
225                 230                 235                 240 


Ser Ser Trp Val Leu Ala Gln His Tyr Val Gly Asn Ala Thr Ala Phe 
                245                 250                 255     


Phe Ile Leu Pro Asp Pro Lys Lys Met Trp Gln Leu Glu Glu Lys Leu 
            260                 265                 270         


Thr Tyr Ser His Leu Glu Asn Ile Gln Arg Ala Phe Asp Ile Arg Ser 
        275                 280                 285             


Ile Asn Leu His Phe Pro Lys Leu Ser Ile Ser Gly Thr Tyr Lys Leu 
    290                 295                 300                 


Lys Arg Val Pro Arg Asn Leu Gly Ile Thr Lys Ile Phe Ser Asn Glu 
305                 310                 315                 320 


Ala Asp Leu Ser Gly Val Ser Gln Glu Ala Pro Leu Lys Leu Ser Lys 
                325                 330                 335     


Ala Val His Val Ala Val Leu Thr Ile Asp Glu Lys Gly Thr Glu Ala 
            340                 345                 350         


Thr Gly Ala Pro His Leu Glu Glu Lys Ala Trp Ser Lys Tyr Gln Thr 
        355                 360                 365             


Val Met Phe Asn Arg Pro Phe Leu Val Ile Ile Lys Glu Tyr Ile Thr 
    370                 375                 380                 


Asn Phe Pro Leu Phe Ile Gly Lys Val Val Asn Pro Thr Gln Lys 
385                 390                 395                 


<210>  1673
<211>  375
<212>  PRT
<213>  Homo Sapiens

<400>  1673

Met Asp Ala Leu Gln Leu Ala Asn Ser Ala Phe Ala Val Asp Leu Phe 
1               5                   10                  15      


Lys Gln Leu Cys Glu Lys Glu Pro Leu Gly Asn Val Leu Phe Ser Pro 
            20                  25                  30          


Ile Cys Leu Ser Thr Ser Leu Ser Leu Ala Gln Val Gly Ala Lys Gly 
        35                  40                  45              


Asp Thr Ala Asn Glu Ile Gly Gln Val Leu His Phe Glu Asn Val Lys 
    50                  55                  60                  


Asp Val Pro Phe Gly Phe Gln Thr Val Thr Ser Asp Val Asn Lys Leu 
65                  70                  75                  80  


Ser Ser Phe Tyr Ser Leu Lys Leu Ile Lys Arg Leu Tyr Val Asp Lys 
                85                  90                  95      


Ser Leu Asn Leu Ser Thr Glu Phe Ile Ser Ser Thr Lys Arg Pro Tyr 
            100                 105                 110         


Ala Lys Glu Leu Glu Thr Val Asp Phe Lys Asp Lys Leu Glu Glu Thr 
        115                 120                 125             


Lys Gly Gln Ile Asn Asn Ser Ile Lys Asp Leu Thr Asp Gly His Phe 
    130                 135                 140                 


Glu Asn Ile Leu Ala Asp Asn Ser Val Asn Asp Gln Thr Lys Ile Leu 
145                 150                 155                 160 


Val Val Asn Ala Ala Tyr Phe Val Gly Lys Trp Met Lys Lys Phe Ser 
                165                 170                 175     


Glu Ser Glu Thr Lys Glu Cys Pro Phe Arg Val Asn Lys Thr Asp Thr 
            180                 185                 190         


Lys Pro Val Gln Met Met Asn Met Glu Ala Thr Phe Cys Met Gly Asn 
        195                 200                 205             


Ile Asp Ser Ile Asn Cys Lys Ile Ile Glu Leu Pro Phe Gln Asn Lys 
    210                 215                 220                 


His Leu Ser Met Phe Ile Leu Leu Pro Lys Asp Val Glu Asp Glu Ser 
225                 230                 235                 240 


Thr Gly Leu Glu Lys Ile Glu Lys Gln Leu Asn Ser Glu Ser Leu Ser 
                245                 250                 255     


Gln Trp Thr Asn Pro Ser Thr Met Ala Asn Ala Lys Val Lys Leu Ser 
            260                 265                 270         


Ile Pro Lys Phe Lys Val Glu Lys Met Ile Asp Pro Lys Ala Cys Leu 
        275                 280                 285             


Glu Asn Leu Gly Leu Lys His Ile Phe Ser Glu Asp Thr Ser Asp Phe 
    290                 295                 300                 


Ser Gly Met Ser Glu Thr Lys Gly Val Ala Leu Ser Asn Val Ile His 
305                 310                 315                 320 


Lys Val Cys Leu Glu Ile Thr Glu Asp Gly Gly Asp Ser Ile Glu Val 
                325                 330                 335     


Pro Gly Ala Arg Ile Leu Gln His Lys Asp Glu Leu Asn Ala Asp His 
            340                 345                 350         


Pro Phe Ile Tyr Ile Ile Arg His Asn Lys Thr Arg Asn Ile Ile Phe 
        355                 360                 365             


Phe Gly Lys Phe Cys Ser Pro 
    370                 375 


<210>  1674
<211>  432
<212>  PRT
<213>  Homo Sapiens

<400>  1674

His Gly Ser Pro Val Asp Ile Cys Thr Ala Lys Pro Arg Asp Ile Pro 
1               5                   10                  15      


Met Asn Pro Met Cys Ile Tyr Arg Ser Pro Glu Lys Lys Ala Thr Glu 
            20                  25                  30          


Asp Glu Gly Ser Glu Gln Lys Ile Pro Glu Ala Thr Asn Arg Arg Val 
        35                  40                  45              


Trp Glu Leu Ser Lys Ala Asn Ser Arg Phe Ala Thr Thr Phe Tyr Gln 
    50                  55                  60                  


His Leu Ala Asp Ser Lys Asn Asp Asn Asp Asn Ile Phe Leu Ser Pro 
65                  70                  75                  80  


Leu Ser Ile Ser Thr Ala Phe Ala Met Thr Lys Leu Gly Ala Cys Asn 
                85                  90                  95      


Asp Thr Leu Gln Gln Leu Met Glu Val Phe Lys Phe Asp Thr Ile Ser 
            100                 105                 110         


Glu Lys Thr Ser Asp Gln Ile His Phe Phe Phe Ala Lys Leu Asn Cys 
        115                 120                 125             


Arg Leu Tyr Arg Lys Ala Asn Lys Ser Ser Lys Leu Val Ser Ala Asn 
    130                 135                 140                 


Arg Leu Phe Gly Asp Lys Ser Leu Thr Phe Asn Glu Thr Tyr Gln Asp 
145                 150                 155                 160 


Ile Ser Glu Leu Val Tyr Gly Ala Lys Leu Gln Pro Leu Asp Phe Lys 
                165                 170                 175     


Glu Asn Ala Glu Gln Ser Arg Ala Ala Ile Asn Lys Trp Val Ser Asn 
            180                 185                 190         


Lys Thr Glu Gly Arg Ile Thr Asp Val Ile Pro Ser Glu Ala Ile Asn 
        195                 200                 205             


Glu Leu Thr Val Leu Val Leu Val Asn Thr Ile Tyr Phe Lys Gly Leu 
    210                 215                 220                 


Trp Lys Ser Lys Phe Ser Pro Glu Asn Thr Arg Lys Glu Leu Phe Tyr 
225                 230                 235                 240 


Lys Ala Asp Gly Glu Ser Cys Ser Ala Ser Met Met Tyr Gln Glu Gly 
                245                 250                 255     


Lys Phe Arg Tyr Arg Arg Val Ala Glu Gly Thr Gln Val Leu Glu Leu 
            260                 265                 270         


Pro Phe Lys Gly Asp Asp Ile Thr Met Val Leu Ile Leu Pro Lys Pro 
        275                 280                 285             


Glu Lys Ser Leu Ala Lys Val Glu Lys Glu Leu Thr Pro Glu Val Leu 
    290                 295                 300                 


Gln Glu Trp Leu Asp Glu Leu Glu Glu Met Met Leu Val Val His Met 
305                 310                 315                 320 


Pro Arg Phe Arg Ile Glu Asp Gly Phe Ser Leu Lys Glu Gln Leu Gln 
                325                 330                 335     


Asp Met Gly Leu Val Asp Leu Phe Ser Pro Glu Lys Ser Lys Leu Pro 
            340                 345                 350         


Gly Ile Val Ala Glu Gly Arg Asp Asp Leu Tyr Val Ser Asp Ala Phe 
        355                 360                 365             


His Lys Ala Phe Leu Glu Val Asn Glu Glu Gly Ser Glu Ala Ala Ala 
    370                 375                 380                 


Ser Thr Ala Val Val Ile Ala Gly Arg Ser Leu Asn Pro Asn Arg Val 
385                 390                 395                 400 


Thr Phe Lys Ala Asn Arg Pro Phe Leu Val Phe Ile Arg Glu Val Pro 
                405                 410                 415     


Leu Asn Thr Ile Ile Phe Met Gly Arg Val Ala Asn Pro Cys Val Lys 
            420                 425                 430         


<210>  1675
<211>  404
<212>  PRT
<213>  Homo Sapiens

<400>  1675

His Leu Arg Glu Gly Met Thr Leu Leu Lys Thr Glu Phe Ala Leu His 
1               5                   10                  15      


Leu Tyr Gln Ser Val Ala Ala Cys Arg Asn Glu Thr Asn Phe Val Ile 
            20                  25                  30          


Ser Pro Ala Gly Val Ser Leu Pro Leu Glu Ile Leu Gln Phe Gly Ala 
        35                  40                  45              


Glu Gly Ser Thr Gly Gln Gln Leu Ala Asp Ala Leu Gly Tyr Thr Val 
    50                  55                  60                  


His Asp Lys Arg Val Lys Asp Phe Leu His Ala Val Tyr Ala Thr Leu 
65                  70                  75                  80  


Pro Thr Ser Ser Gln Gly Thr Glu Met Glu Leu Ala Cys Ser Leu Phe 
                85                  90                  95      


Val Gln Val Gly Thr Pro Leu Ser Pro Cys Phe Val Glu His Val Ser 
            100                 105                 110         


Trp Trp Ala Asn Ser Ser Leu Glu Pro Ala Asp Leu Ser Glu Pro Asn 
        115                 120                 125             


Ser Thr Ala Ile Gln Thr Ser Glu Gly Ala Ser Arg Glu Thr Ala Gly 
    130                 135                 140                 


Gly Gly Pro Ser Glu Gly Pro Gly Gly Trp Pro Trp Glu Gln Val Ser 
145                 150                 155                 160 


Ala Ala Phe Ala Gln Leu Val Leu Val Ser Thr Met Ser Phe Gln Gly 
                165                 170                 175     


Thr Trp Arg Lys Arg Phe Ser Ser Thr Asp Thr Gln Ile Leu Pro Phe 
            180                 185                 190         


Thr Cys Ala Tyr Gly Leu Val Leu Gln Val Pro Met Met His Gln Thr 
        195                 200                 205             


Thr Glu Val Asn Tyr Gly Gln Phe Gln Asp Thr Ala Gly His Gln Val 
    210                 215                 220                 


Gly Val Leu Glu Leu Pro Tyr Leu Gly Ser Ala Val Ser Leu Phe Leu 
225                 230                 235                 240 


Val Leu Pro Arg Asp Lys Asp Thr Pro Leu Ser His Ile Glu Pro His 
                245                 250                 255     


Leu Thr Ala Ser Thr Ile His Leu Trp Thr Thr Ser Leu Arg Arg Ala 
            260                 265                 270         


Arg Met Asp Val Phe Leu Pro Arg Phe Arg Ile Gln Asn Gln Phe Asn 
        275                 280                 285             


Leu Lys Ser Ile Leu Asn Ser Trp Gly Val Thr Asp Leu Phe Asp Pro 
    290                 295                 300                 


Leu Lys Ala Asn Leu Lys Gly Ile Ser Gly Gln Asp Gly Phe Tyr Val 
305                 310                 315                 320 


Ser Glu Ala Ile His Lys Ala Lys Ile Glu Val Leu Glu Glu Gly Thr 
                325                 330                 335     


Lys Ala Ser Gly Ala Thr Ala Leu Leu Leu Leu Lys Arg Ser Arg Ile 
            340                 345                 350         


Pro Ile Phe Lys Ala Asp Arg Pro Phe Ile Tyr Phe Leu Arg Glu Pro 
        355                 360                 365             


Asn Thr Gly Ile Thr Val Phe Phe Asp Arg Ile Gln Ile Ile Tyr Gln 
    370                 375                 380                 


Cys Leu Ser Ser Asn Lys Gly Ser Phe Val His Tyr Pro Leu Lys Asn 
385                 390                 395                 400 


Lys His Ser Phe 
                


<210>  1676
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  1676

Thr Gly Ala Thr Phe Pro Glu Glu Ala Ile Ala Asp Leu Ser Val Asn 
1               5                   10                  15      


Met Tyr Asn Arg Leu Arg Ala Thr Gly Glu Asp Glu Asn Ile Leu Phe 
            20                  25                  30          


Ser Pro Leu Ser Ile Ala Leu Ala Met Gly Met Met Glu Leu Gly Ala 
        35                  40                  45              


Gln Gly Ser Thr Gln Lys Glu Ile Arg His Ser Met Gly Tyr Asp Ser 
    50                  55                  60                  


Leu Lys Asn Gly Glu Glu Phe Ser Phe Leu Lys Glu Phe Ser Asn Met 
65                  70                  75                  80  


Val Thr Ala Lys Glu Ser Gln Tyr Val Met Lys Ile Ala Asn Ser Leu 
                85                  90                  95      


Phe Val Gln Asn Gly Phe His Val Asn Glu Glu Phe Leu Gln Met Met 
            100                 105                 110         


Lys Lys Tyr Phe Asn Ala Ala Val Asn His Val Asp Phe Ser Gln Asn 
        115                 120                 125             


Val Ala Val Ala Asn Tyr Ile Asn Lys Trp Val Glu Asn Asn Thr Asn 
    130                 135                 140                 


Asn Leu Val Lys Asp Leu Val Ser Pro Arg Asp Phe Asp Ala Ala Thr 
145                 150                 155                 160 


Tyr Leu Ala Leu Ile Asn Ala Val Tyr Phe Lys Gly Asn Trp Lys Ser 
                165                 170                 175     


Gln Phe Arg Pro Glu Asn Thr Arg Thr Phe Ser Phe Thr Lys Asp Asp 
            180                 185                 190         


Glu Ser Glu Val Gln Ile Pro Met Met Tyr Gln Gln Gly Glu Phe Tyr 
        195                 200                 205             


Tyr Gly Glu Phe Ser Asp Gly Ser Asn Glu Ala Gly Gly Ile Tyr Gln 
    210                 215                 220                 


Val Leu Glu Ile Pro Tyr Glu Gly Asp Glu Ile Ser Met Met Leu Val 
225                 230                 235                 240 


Leu Ser Arg Gln Glu Val Pro Leu Ala Thr Leu Glu Pro Leu Val Lys 
                245                 250                 255     


Ala Gln Leu Val Glu Glu Trp Ala Asn Ser Val Lys Lys Gln Lys Val 
            260                 265                 270         


Glu Val Tyr Leu Pro Arg Phe Thr Val Glu Gln Glu Ile Asp Leu Lys 
        275                 280                 285             


Asp Val Leu Lys Ala Leu Gly Ile Thr Glu Ile Phe Ile Lys Asp Ala 
    290                 295                 300                 


Asn Leu Thr Gly Leu Ser Asp Asn Lys Glu Ile Phe Leu Ser Lys Ala 
305                 310                 315                 320 


Ile His Lys Ser Phe Leu Glu Val Asn Glu Glu Gly Ser Glu Ala Ala 
                325                 330                 335     


Ala Val Ser Gly Met Ile Ala Ile Ser Arg Met Ala Val Leu Tyr Pro 
            340                 345                 350         


Gln Val Ile Val Asp His Pro Phe Phe Phe Leu Ile Arg Asn Arg Arg 
        355                 360                 365             


Thr Gly Thr Ile Leu Phe Met Gly Arg Val Met His Pro Glu Thr Met 
    370                 375                 380                 


Asn Thr Ser Gly His Asp Phe Glu Glu Leu 
385                 390                 


<210>  1677
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  1677

Met Arg Ala Gly Phe Ser Asp Phe Gln Leu Ile Arg Asp Gln Val Leu 
1               5                   10                  15      


Phe Leu Gln Asp Gln Ala Gln Arg Leu Thr Glu Trp Leu Gln Leu Ser 
            20                  25                  30          


Gly Phe Glu Asn Pro Val Ser Glu Ser Thr Thr Leu Cys Leu Arg Glu 
        35                  40                  45              


Arg Glu Lys Arg Ile Pro Thr Cys Val Ala Val Cys Val Pro Ser Pro 
    50                  55                  60                  


Gly Thr Val His Thr Ala Leu Leu His Pro Thr Thr Leu Ser Gln Ser 
65                  70                  75                  80  


Arg Ser Ser Ser Glu Ala Lys Met Leu Ile Ile His Thr Ala 
                85                  90                  


<210>  1678
<211>  233
<212>  PRT
<213>  Homo Sapiens

<400>  1678

Lys Val Met Trp Phe Ser Pro Ala Gly Met Gly His Leu Cys Val Thr 
1               5                   10                  15      


Lys Asp Gly Leu Arg Leu Glu Gly Glu Ser Glu Phe Leu Phe Pro Leu 
            20                  25                  30          


Tyr Ala Lys Glu Ile His Ser Arg Val Asp Ser Ser Leu Leu Leu Gln 
        35                  40                  45              


Ser Thr Gln Asn Val Thr Val Asn Ala Arg Asn Ser Glu Gly Glu Val 
    50                  55                  60                  


Thr Gly Arg Leu Lys Val Gly Pro Lys Met Val Glu Val Gln Asn Gln 
65                  70                  75                  80  


Gln Phe Gln Ile Asn Ser Asn Asp Gly Lys Pro Leu Phe Thr Val Asp 
                85                  90                  95      


Glu Lys Glu Val Val Val Gly Thr Asp Lys Leu Arg Val Thr Gly Pro 
            100                 105                 110         


Glu Gly Ala Leu Phe Glu His Ser Val Glu Thr Pro Leu Val Arg Ala 
        115                 120                 125             


Asp Pro Phe Gln Asp Leu Arg Leu Glu Ser Pro Thr Arg Ser Leu Ser 
    130                 135                 140                 


Met Asp Ala Pro Arg Gly Val His Ile Gln Ala His Ala Gly Lys Ile 
145                 150                 155                 160 


Glu Ala Leu Ser Gln Met Asp Ile Leu Phe His Ser Ser Asp Gly Met 
                165                 170                 175     


Leu Val Leu Asp Ala Glu Thr Val Cys Leu Pro Lys Leu Val Gln Gly 
            180                 185                 190         


Thr Trp Gly Pro Ser Gly Ser Ser Gln Ser Leu Tyr Glu Ile Cys Val 
        195                 200                 205             


Cys Pro Asp Gly Lys Leu Tyr Leu Ser Val Ala Gly Val Ser Thr Thr 
    210                 215                 220                 


Cys Gln Glu His Asn His Ile Cys Leu 
225                 230             


<210>  1679
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  1679

Lys Val Met Asn Phe Thr Val Asp Gly Met Gly Asn Leu Arg Val Thr 
1               5                   10                  15      


Lys Lys Gly Ile Arg Leu Glu Gly Ile Ser Glu Phe Leu Leu Pro Leu 
            20                  25                  30          


Tyr Val Lys Glu Ile His Ser Arg Lys Asp Ser Pro Leu Val Leu Gln 
        35                  40                  45              


Ser Asp Arg Asn Val Thr Val Asn Ala Arg Asn His Met Gly Gln Leu 
    50                  55                  60                  


Thr Gly Gln Leu Thr Ile Gly Ala Asp Ala Val Glu Ala Gln Cys Lys 
65                  70                  75                  80  


Arg Phe Glu Val Arg Ala Ser Glu Asp Gly Arg Val Leu Phe Ser Ala 
                85                  90                  95      


Asp Glu Asp Glu Ile Thr Ile Gly Ala Glu Lys Leu Lys Val Thr Gly 
            100                 105                 110         


Thr Glu Gly Ala Val Phe Gly His Ser Val Glu Thr Pro His Ile Arg 
        115                 120                 125             


Ala Glu Pro Ser Gln Asp Leu Arg Leu Glu Ser Pro Thr Arg Ser Leu 
    130                 135                 140                 


Ile Met Glu Ala Pro Arg Gly Val Gln Val Ser Ala Ala Ala Gly Asp 
145                 150                 155                 160 


Phe Lys Ala Thr Cys Arg Lys Glu Leu His Leu Gln Ser Thr Glu Gly 
                165                 170                 175     


Glu Ile Phe Leu Asn Ala Glu Thr Ile Lys Leu Gly Asn Leu Pro Thr 
            180                 185                 190         


Gly Ser Phe Ser Ser Ser Ser Pro Ser Ser Ser Ser Ser Arg Gln Thr 
        195                 200                 205             


Val Tyr Glu Leu Cys Val Cys Pro Asn Gly Lys Leu Tyr Leu Ser Pro 
    210                 215                 220                 


Ala Gly Val Gly Ser Thr Cys Gln Ser Ser Ser Asn Ile Cys Leu Trp 
225                 230                 235                 240 


Ser 
    


<210>  1680
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1680

Glu Val Cys Met Ala Ser Arg Gly Leu Ser Leu Phe Pro Glu Ser Cys 
1               5                   10                  15      


Pro Asp Phe Cys Cys Gly Thr Cys Asp Asp Gln Tyr Cys Cys Ser Asp 
            20                  25                  30          


Val Leu Lys Lys Phe Val Trp Ser Glu Glu Arg Cys Ala Val Pro Glu 
        35                  40                  45              


Ala Ser Val Pro Ala Ser Val Glu Pro Val Glu Gln Leu Gly Ser Ala 
    50                  55                  60                  


Leu Arg Phe Arg Pro Gly Tyr Asn Asp Pro Met Ser Gly 
65                  70                  75          


<210>  1681
<211>  149
<212>  PRT
<213>  Homo Sapiens

<400>  1681

Ala Arg Gly Arg Ala Ala Asn Arg Thr Leu Ser Ala Gly Gly Ala Ala 
1               5                   10                  15      


Val Gly Gly Arg Arg Ala Gly Gly Ala Leu Ala Arg Gly Gly Arg Glu 
            20                  25                  30          


Leu Asn Gly Thr Ala Arg Ala Pro Gly Ile Pro Glu Ala Gly Ser Arg 
        35                  40                  45              


Arg Gly Gln Pro Ala Ala Ala Val Ala Ala Ala Ala Ser Ala Ala Val 
    50                  55                  60                  


Thr Tyr Glu Thr Cys Trp Gly Tyr Tyr Asp Val Ser Gly Gln Tyr Asp 
65                  70                  75                  80  


Lys Glu Phe Glu Cys Asn Asn Ser Glu Ser Gly Tyr Leu Tyr Cys Cys 
                85                  90                  95      


Gly Thr Cys Tyr Tyr Arg Phe Cys Cys Lys Lys Arg His Glu Lys Leu 
            100                 105                 110         


Asp Gln Arg Gln Cys Thr Asn Tyr Gln Ser Pro Val Trp Val Gln Thr 
        115                 120                 125             


Pro Ser Thr Lys Val Val Ser Pro Gly Pro Glu Asn Lys Tyr Asp Pro 
    130                 135                 140                 


Glu Lys Asp Lys Thr 
145                 


<210>  1682
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  1682

Arg Pro Ser Asn Ala Thr Ser Ala Glu Pro Ala Gly Pro Leu Pro Ala 
1               5                   10                  15      


Leu Leu Ala His Leu Arg Arg Leu Thr Gly Ala Leu Thr Gly Gly Gly 
            20                  25                  30          


Gly Ala Ala Ser Pro Gly Ala Asn Gly Thr Arg Thr Gly Pro Ala Gly 
        35                  40                  45              


Gly Ala Gly Ala Ala Ala Arg Ala Pro Pro Pro Ala Glu Leu Cys His 
    50                  55                  60                  


Gly Tyr Tyr Asp Val Met Gly Gln Tyr Asp Ala Thr Phe Asn Cys Ser 
65                  70                  75                  80  


Thr Gly Ser Tyr Arg Phe Cys Cys Gly Thr Cys His Tyr Arg Phe Cys 
                85                  90                  95      


Cys Glu His Arg His Met Arg Leu Ala Gln Ala Ser Cys Ser Asn Tyr 
            100                 105                 110         


Asp Thr Pro Arg Trp Ala Thr Thr Pro Pro Pro Leu Ala Gly Gly Ala 
        115                 120                 125             


Gly Gly Ala Gly Gly Ala Gly Gly Gly Pro Gly Pro Gly Gln Ala Gly 
    130                 135                 140                 


Trp Leu Glu Gly Gly Arg Thr Gly Gly Ala Gly Gly Arg Gly Gly Glu 
145                 150                 155                 160 


Gly Pro Gly Gly Ser Thr Ala 
                165         


<210>  1683
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  1683

Gly Ala Pro Glu Ala Gln Gly Pro Ala Ala Pro Gly Thr Thr Ala Pro 
1               5                   10                  15      


Glu Gly Gly Asp Arg Cys Arg Gly Tyr Tyr Asp Val Met Gly Gln Trp 
            20                  25                  30          


Asp Pro Pro Phe Asn Cys Ser Ser Gly Ala Tyr Ser Phe Cys Cys Gly 
        35                  40                  45              


Thr Cys Gly Tyr Arg Phe Cys Cys His Asp Gly Pro Arg Arg Leu Asp 
    50                  55                  60                  


Gln Ser Arg Cys Ser Asn Tyr Asp Thr Pro Ala Trp Val Gln Thr Gly 
65                  70                  75                  80  


Arg Pro Pro Ala Arg Ala Arg Asp Thr Ala Ala Pro Arg Asp Pro Gly 
                85                  90                  95      


Arg Glu Arg Ser 
            100 


<210>  1684
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  1684

Gln Glu Arg Ala Gly His Gly Gln Leu Ala Gln Leu Gly Gly Val Leu 
1               5                   10                  15      


Leu Leu Ala Gly Gly Asn Arg Ser Gly Ala Ala Ser Gly Glu Ala Ser 
            20                  25                  30          


Glu Gly Ala Glu Ala Ser Asp Ala Pro Pro Thr Arg Ala Pro Thr Pro 
        35                  40                  45              


Asp Phe Cys Arg Gly Tyr Phe Asp Val Met Gly Gln Trp Asp Pro Pro 
    50                  55                  60                  


Phe Asn Cys Ser Ser Gly Asp Phe Ile Phe Cys Cys Gly Thr Cys Gly 
65                  70                  75                  80  


Phe Arg Phe Cys Cys Thr Phe Lys Lys Arg Arg Leu Asn Gln Ser Thr 
                85                  90                  95      


Cys Thr Asn Tyr Asp Thr Pro Leu Trp Leu Asn Thr Gly Lys Pro Pro 
            100                 105                 110         


Ala Arg Lys Asp Asp Pro Leu His Asp Pro Thr Lys Asp Lys 
        115                 120                 125     


<210>  1685
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  1685

Glu Glu Glu Leu Gln Val Ile Gln Pro Asp Lys Ser Ile Ser Val Ala 
1               5                   10                  15      


Ala Gly Glu Ser Ala Thr Leu His Cys Thr Val Thr Ser Leu Ile Pro 
            20                  25                  30          


Val Gly Pro Ile Gln Trp Phe Arg Gly Ala Gly Pro Gly Arg Glu Leu 
        35                  40                  45              


Ile Tyr Asn Gln Lys Glu Gly His Phe Pro Arg Val Thr Thr Val Ser 
    50                  55                  60                  


Asp Leu Thr Lys Arg Asn Asn Met Asp Phe Ser Ile Arg Ile Ser Asn 
65                  70                  75                  80  


Ile Thr Pro Ala Asp Ala Gly Thr Tyr Tyr Cys Val Lys Phe Arg Lys 
                85                  90                  95      


Gly Ser Pro Asp His Val Glu Phe Lys Ser Gly Ala Gly Thr Glu Leu 
            100                 105                 110         


Ser Val Arg Ala Lys Pro Ser Ala Pro Val Val Ser Gly Pro Ala Ala 
        115                 120                 125             


Arg Ala Thr Pro Gln His Thr Val Ser Phe Thr Cys Glu Ser His Gly 
    130                 135                 140                 


Phe Ser Pro Arg Asp Ile Thr Leu Lys Trp Phe Lys Asn Gly Asn Glu 
145                 150                 155                 160 


Leu Ser Asp Phe Gln Thr Asn Val Asp Pro Ala Gly Asp Ser Val Ser 
                165                 170                 175     


Tyr Ser Ile His Ser Thr Ala Lys Val Val Leu Thr Arg Glu Asp Val 
            180                 185                 190         


His Ser Gln Val Ile Cys Glu Val Ala His Val Thr Leu Gln Gly Asp 
        195                 200                 205             


Pro Leu Arg Gly Thr Ala Asn Leu Ser Glu Thr Ile Arg Val Pro Pro 
    210                 215                 220                 


Thr Leu Glu Val Thr Gln Gln Pro Val Arg Ala Glu Asn Gln Val Asn 
225                 230                 235                 240 


Val Thr Cys Gln Val Arg Lys Phe Tyr Pro Gln Arg Leu Gln Leu Thr 
                245                 250                 255     


Trp Leu Glu Asn Gly Asn Val Ser Arg Thr Glu Thr Ala Ser Thr Leu 
            260                 265                 270         


Thr Glu Asn Lys Asp Gly Thr Tyr Asn Trp Met Ser Trp Leu Leu Val 
        275                 280                 285             


Asn Val Ser Ala His Arg Asp Asp Val Lys Leu Thr Cys Gln Val Glu 
    290                 295                 300                 


His Asp Gly Gln Pro Ala Val Ser Lys Ser His Asp Leu Lys Val Ser 
305                 310                 315                 320 


Ala His Pro Lys Glu Gln Gly Ser Asn Thr Ala Pro Gly Pro Ala Leu 
                325                 330                 335     


Ala Ser Ala Ala Pro Leu 
            340         


<210>  1686
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  1686

Leu Glu Asn Phe Ala Ala Ala Ile Pro Gly His Arg Cys Trp Val His 
1               5                   10                  15      


Met Leu Asp Asn Asn Thr Gly Ser Gly Asn Glu Thr Gly Ile Leu Ser 
            20                  25                  30          


Glu Asp Ala Leu Leu Arg Ile Ser Ile Pro Leu Asp Ser Asn Leu Arg 
        35                  40                  45              


Pro Glu Lys Cys Arg Arg Phe Val His Pro Gln Trp Gln Leu Leu His 
    50                  55                  60                  


Leu Asn Gly Thr Ile His Ser Thr Ser Glu Ala Asp Thr Glu Pro Cys 
65                  70                  75                  80  


Val Asp Gly Trp Val Tyr Asp Gln Ser Tyr Phe Pro Ser Thr Ile Val 
                85                  90                  95      


Thr Lys Trp Asp Leu Val Cys Asp Tyr Gln Ser Leu Lys 
            100                 105                 


<210>  1687
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1687

Met Val Leu Asp Glu Pro His His Cys Ala Val Ala Trp Val Lys Asn 
1               5                   10                  15      


His Thr Phe Asn Leu Ser Ala Ala Glu Gln Leu Val Leu Ser Val Pro 
            20                  25                  30          


Leu Asp Thr Ala Gly His Pro Glu Pro Cys Leu Met Phe Arg Pro Pro 
        35                  40                  45              


Pro Ala Asn Ala Ser Leu Gln Asp Ile Leu Ser His Arg Phe Asn Glu 
    50                  55                  60                  


Thr Gln Pro Cys Asp Met Gly Trp Glu Tyr Pro Glu Asn Arg Leu Pro 
65                  70                  75                  80  


Ser Leu Lys Asn Glu Phe Asn Leu Val Cys Asp Arg Lys His Leu Lys 
                85                  90                  95      


Asp 
    


<210>  1688
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  1688

Gly Phe Thr Pro Asp His Arg Cys Arg Ser Pro Gly Val Ala Glu Leu 
1               5                   10                  15      


Ser Leu Arg Cys Gly Trp Ser Pro Ala Glu Glu Leu Asn Tyr Thr Val 
            20                  25                  30          


Pro Gly Pro Gly Pro Ala Gly Glu Ala Ser Pro Arg Gln Cys Arg Arg 
        35                  40                  45              


Tyr Glu Val Asp Trp Asn Gln Ser Thr Phe Asp Cys Val Asp Pro Leu 
    50                  55                  60                  


Ala Ser Leu Asp Thr Asn Arg Ser Arg Leu Pro Leu Gly Pro Cys Arg 
65                  70                  75                  80  


Asp Gly Trp Val Tyr Glu Thr Pro Gly Ser Ser Ile Val Thr Glu Phe 
                85                  90                  95      


Asn Leu Val Cys Ala Asn Ser Trp Met Leu Asp 
            100                 105         


<210>  1689
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1689

Pro Pro His His Cys Arg Gly Pro Ala Asn His Thr Glu Ala Ser Thr 
1               5                   10                  15      


Asn Asp Ser Gly Ala Trp Leu Arg Ala Thr Ile Pro Leu Asp Gln Leu 
            20                  25                  30          


Gly Ala Pro Glu Pro Cys Arg Arg Phe Thr Lys Pro Gln Trp Ala Leu 
        35                  40                  45              


Leu Ser Pro Asn Ser Ser Ile Pro Gly Ala Ala Thr Glu Gly Cys Lys 
    50                  55                  60                  


Asp Gly Trp Val Tyr Asn Arg Ser Val Phe Pro Ser Thr Ile Val Met 
65                  70                  75                  80  


Glu Trp Asp Leu Val Cys Glu Ala Arg Thr Leu Arg Asp 
                85                  90              


<210>  1690
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  1690

Val Tyr His Gln Thr Gln Leu Glu Asn Phe Ala Ala Phe Ile Leu Asp 
1               5                   10                  15      


His Arg Cys Trp Val His Ile Leu Asp Asn Asp Thr Ile Pro Asp Asn 
            20                  25                  30          


Asp Pro Gly Thr Leu Ser Gln Asp Ala Leu Leu Arg Ile Ser Ile Pro 
        35                  40                  45              


Phe Asp Ser Asn Leu Arg Pro Glu Lys Cys Arg Arg Phe Val His Pro 
    50                  55                  60                  


Gln Trp Lys Leu Ile His Leu Asn Gly Thr Phe Pro Asn Thr Ser Glu 
65                  70                  75                  80  


Pro Asp Thr Glu Pro Cys Val Asp Gly Trp Val Tyr Asp Gln Ser Ser 
                85                  90                  95      


Phe Pro Ser Thr Ile Val Thr Lys Trp Asp Leu Val Cys Glu Ser Gln 
            100                 105                 110         


Pro Leu Asn 
        115 


<210>  1691
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  1691

Gln Pro Ala Pro His Cys Arg Pro Asp Pro Thr Leu Leu Pro Pro Ala 
1               5                   10                  15      


Leu Arg Ala Leu Arg Gly Pro Ala Leu Leu Asp Ala Ala Ile Pro Arg 
            20                  25                  30          


Leu Gly Pro Thr Arg Ala Pro Ala Glu Ala Leu Gly Val Leu Ser Pro 
        35                  40                  45              


Ser Tyr Leu Ala Pro Leu Thr Arg Ala Pro Arg Pro Ser Ser Trp Ala 
    50                  55                  60                  


Ser Cys Ser Gly Ala Ala Ala Gly Pro Thr Trp Asn Leu Val Cys Gly 
65                  70                  75                  80  


Asp Gly Trp Lys 
                


<210>  1692
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  1692

Asn Ala Pro Gln Gln Val Ile Ile Ser His Tyr Arg His Val Leu Gly 
1               5                   10                  15      


Val Pro Leu Asp Asp Arg Lys Ala Ile Asn Asn Tyr Val Ile Asn Ser 
            20                  25                  30          


Thr Asp Glu Leu Pro Thr Ile Ser Tyr Ser Met Asn Pro Lys Pro Thr 
        35                  40                  45              


Pro Trp Ala Glu Glu Glu Thr Val Ala Ala Ala Gln Leu Ile Thr Met 
    50                  55                  60                  


Leu Trp Ser 
65          


<210>  1693
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  1693

Glu Ser Ala Thr Ala Leu Leu Glu Arg Leu Ser Glu Leu Ala Leu Gly 
1               5                   10                  15      


Ala Ala Ser Leu Thr Pro Arg Ala Gln Ala Pro Asp Ile Leu Lys Val 
            20                  25                  30          


Leu Thr Lys Pro Leu Thr His Leu Ile Val Gln Leu Asp Ser Asp Met 
        35                  40                  45              


Ile Met Ser Ser Ala Thr Gly Asn Ala Thr Asn Ser Ser Leu Ile Lys 
    50                  55                  60                  


His Trp Cys Gly Thr Thr Gly Gln Pro Thr Gln Glu Asn Ser Ser Cys 
65                  70                  75                  80  


Gly Ala Phe Gly Pro Cys Thr Glu Lys Asn Ser Thr Ala Pro Ala Asp 
                85                  90                  95      


Arg Leu Pro Cys Arg His Leu Phe Ala Gly Thr Glu Leu Thr Asp Leu 
            100                 105                 110         


Ala 
    


<210>  1694
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  1694

Met Asp Pro Met Glu Leu Arg Asn Val Asn Ile Glu Pro Asp Asp Glu 
1               5                   10                  15      


Ser Ser Ser Gly Glu Ser Ala Pro Asp Ser Tyr Ile Gly Ile Gly Asn 
            20                  25                  30          


Ser Glu Lys Ala Ala Met Ser Ser Gln Phe Ala Asn Glu Asp Thr Glu 
        35                  40                  45              


Ser Gln Lys Phe Leu Thr Asn Gly Phe Leu Gly Lys Lys Lys Leu Ala 
    50                  55                  60                  


Asp Tyr Ala Asp Glu His His Pro Gly Thr Thr Ser Phe Gly Met Ser 
65                  70                  75                  80  


Ser Phe Asn Leu Ser Asn Ala Ile Met Gly Ser Gly Ile Leu Gly Leu 
                85                  90                  95      


Ser Tyr Ala Met Ala Asn Thr Gly 
            100                 


<210>  1695
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  1695

Ser Ser Trp Glu Val Ser Glu Arg Ile Arg Glu Cys Asn Tyr Tyr Gln 
1               5                   10                  15      


Asn Leu Ala Val Pro Gln Gly Leu Glu Tyr Gln Thr Asn Glu Pro Ser 
            20                  25                  30          


Glu Glu Pro Ile Lys Thr Ile Arg Asn Trp Leu Lys Glu Lys Leu His 
        35                  40                  45              


Val Phe Ser Glu Lys Leu Glu Glu Glu Val Gln Gln Leu Glu Gln Leu 
    50                  55                  60                  


Ala Trp Asp Leu Glu Leu Trp Leu Asp Ala Leu Leu Gly Glu Pro His 
65                  70                  75                  80  


Gln Glu Glu His Cys Ser Thr Tyr Lys Ser His Leu Trp Glu Trp Ala 
                85                  90                  95      


Trp Ala Leu Gly Arg Glu His Lys Gly Gly Glu Gly Leu Leu Glu Ile 
            100                 105                 110         


Ser Leu Ser Gly Ala Glu Leu 
        115                 


<210>  1696
<211>  413
<212>  PRT
<213>  Homo Sapiens

<400>  1696

Glu Pro Gly Lys Phe Trp His Ile Ala Asp Leu His Leu Asp Pro Asp 
1               5                   10                  15      


Tyr Lys Val Ser Lys Asp Pro Phe Gln Val Cys Pro Ser Ala Gly Ser 
            20                  25                  30          


Gln Pro Val Pro Asp Ala Gly Pro Trp Gly Asp Tyr Leu Cys Asp Ser 
        35                  40                  45              


Pro Trp Ala Leu Ile Asn Ser Ser Ile Tyr Ala Met Lys Glu Ile Glu 
    50                  55                  60                  


Pro Glu Pro Asp Phe Ile Leu Trp Thr Gly Asp Asp Thr Pro His Val 
65                  70                  75                  80  


Pro Asp Glu Lys Leu Gly Glu Ala Ala Val Leu Glu Ile Val Glu Arg 
                85                  90                  95      


Leu Thr Lys Leu Ile Arg Glu Val Phe Pro Asp Thr Lys Val Tyr Ala 
            100                 105                 110         


Ala Leu Gly Asn His Asp Phe His Pro Lys Asn Gln Phe Pro Ala Gly 
        115                 120                 125             


Ser Asn Asn Ile Tyr Asn Gln Ile Ala Glu Leu Trp Lys Pro Trp Leu 
    130                 135                 140                 


Ser Asn Glu Ser Ile Ala Leu Phe Lys Lys Gly Ala Phe Tyr Cys Glu 
145                 150                 155                 160 


Lys Leu Pro Gly Pro Ser Gly Ala Gly Arg Ile Val Val Leu Asn Thr 
                165                 170                 175     


Asn Leu Tyr Tyr Thr Ser Asn Ala Leu Thr Ala Asp Met Ala Asp Pro 
            180                 185                 190         


Gly Gln Gln Phe Gln Trp Leu Glu Asp Val Leu Thr Asp Ala Ser Lys 
        195                 200                 205             


Ala Gly Asp Met Val Tyr Ile Val Gly His Val Pro Pro Gly Phe Phe 
    210                 215                 220                 


Glu Lys Thr Gln Asn Lys Ala Trp Phe Arg Glu Gly Phe Asn Glu Lys 
225                 230                 235                 240 


Tyr Leu Lys Val Val Arg Lys His His Arg Val Ile Ala Gly Gln Phe 
                245                 250                 255     


Phe Gly His His His Thr Asp Ser Phe Arg Met Leu Tyr Asp Asp Ala 
            260                 265                 270         


Gly Val Pro Ile Ser Ala Met Phe Ile Thr Pro Gly Val Thr Pro Trp 
        275                 280                 285             


Lys Thr Thr Leu Pro Gly Val Val Asn Gly Ala Asn Asn Pro Ala Ile 
    290                 295                 300                 


Arg Val Phe Glu Tyr Asp Arg Ala Thr Leu Ser Leu Lys Asp Met Val 
305                 310                 315                 320 


Thr Tyr Phe Met Asn Leu Ser Gln Ala Asn Ala Gln Gly Thr Pro Arg 
                325                 330                 335     


Trp Glu Leu Glu Tyr Gln Leu Thr Glu Ala Tyr Gly Val Pro Asp Ala 
            340                 345                 350         


Ser Ala His Ser Met His Thr Val Leu Asp Arg Ile Ala Gly Asp Gln 
        355                 360                 365             


Ser Thr Leu Gln Arg Tyr Tyr Val Tyr Asn Ser Val Ser Tyr Ser Ala 
    370                 375                 380                 


Gly Val Cys Asp Glu Ala Cys Ser Met Gln His Val Cys Ala Met Arg 
385                 390                 395                 400 


Gln Val Asp Ile Asp Ala Tyr Thr Thr Cys Leu Tyr Ala 
                405                 410             


<210>  1697
<211>  532
<212>  PRT
<213>  Homo Sapiens

<400>  1697

Ala Val Leu Gly Phe Leu Gln Glu His Gly Gly Lys Val Arg Asn Ser 
1               5                   10                  15      


Glu Leu Leu Ser Arg Phe Lys Pro Leu Leu Asp Ala Gly Asp Pro Arg 
            20                  25                  30          


Gly Arg Ala Ala Arg Arg Asp Arg Phe Lys Gln Phe Val Asn Asn Val 
        35                  40                  45              


Ala Val Val Lys Glu Leu Asp Gly Val Lys Phe Val Val Leu Arg Lys 
    50                  55                  60                  


Lys Pro Arg Pro Pro Glu Pro Glu Pro Ala Pro Phe Gly Pro Pro Gly 
65                  70                  75                  80  


Ala Ala Ala Gln Pro Ser Lys Pro Thr Ser Thr Val Leu Pro Arg Ser 
                85                  90                  95      


Ala Ser Ala Pro Gly Ala Pro Pro Leu Val Arg Val Pro Arg Pro Val 
            100                 105                 110         


Glu Pro Pro Gly Asp Leu Gly Leu Pro Thr Glu Pro Gln Asp Thr Pro 
        115                 120                 125             


Gly Gly Pro Ala Ser Glu Pro Ala Gln Pro Pro Gly Glu Arg Ser Ala 
    130                 135                 140                 


Asp Pro Pro Leu Pro Ala Leu Glu Leu Ala Gln Ala Thr Glu Arg Pro 
145                 150                 155                 160 


Ser Ala Asp Ala Ala Pro Pro Pro Arg Ala Pro Ser Glu Ala Ala Ser 
                165                 170                 175     


Pro Cys Ser Asp Pro Pro Asp Ala Glu Pro Gly Pro Gly Ala Ala Lys 
            180                 185                 190         


Gly Pro Pro Gln Gln Lys Pro Cys Met Leu Pro Val Arg Cys Val Pro 
        195                 200                 205             


Ala Pro Ala Thr Leu Arg Leu Arg Ala Glu Glu Pro Gly Leu Arg Arg 
    210                 215                 220                 


Gln Leu Ser Glu Glu Pro Ser Pro Arg Ser Ser Pro Leu Leu Leu Arg 
225                 230                 235                 240 


Arg Leu Ser Val Glu Glu Ser Gly Leu Gly Leu Gly Leu Gly Pro Gly 
                245                 250                 255     


Arg Ser Pro His Leu Arg Arg Leu Ser Arg Ala Gly Pro Arg Leu Leu 
            260                 265                 270         


Ser Pro Asp Ala Glu Glu Leu Pro Ala Ala Pro Pro Pro Ser Ala Val 
        275                 280                 285             


Pro Leu Glu Pro Ser Glu His Glu Trp Leu Val Arg Thr Ala Gly Gly 
    290                 295                 300                 


Arg Trp Thr His Gln Leu His Gly Leu Leu Leu Arg Asp Arg Gly Leu 
305                 310                 315                 320 


Ala Ala Lys Arg Asp Phe Met Ser Gly Phe Thr Ala Leu His Trp Ala 
                325                 330                 335     


Ala Lys Ser Gly Asp Gly Glu Met Ala Leu Gln Leu Val Glu Val Ala 
            340                 345                 350         


Arg Arg Ser Gly Ala Pro Val Asp Val Asn Ala Arg Ser His Gly Gly 
        355                 360                 365             


Tyr Thr Pro Leu His Leu Ala Ala Leu His Gly His Glu Asp Ala Ala 
    370                 375                 380                 


Val Leu Leu Val Val Arg Leu Gly Ala Gln Val His Val Arg Asp His 
385                 390                 395                 400 


Ser Gly Arg Arg Ala Tyr Gln Tyr Leu Arg Pro Gly Ser Ser Tyr Ala 
                405                 410                 415     


Leu Arg Arg Leu Leu Gly Asp Pro Gly Leu Arg Gly Thr Thr Glu Pro 
            420                 425                 430         


Asp Ala Thr Gly Gly Gly Ser Gly Ser Leu Ala Ala Arg Arg Pro Val 
        435                 440                 445             


Gln Val Ala Ala Thr Ile Leu Ser Ser Thr Thr Ser Ala Phe Leu Gly 
    450                 455                 460                 


Val Leu Ala Asp Asp Leu Met Leu Gln Asp Leu Ala Arg Gly Leu Lys 
465                 470                 475                 480 


Lys Ser Ser Ser Phe Ser Lys Phe Leu Ser Ala Ser Pro Met Ala Pro 
                485                 490                 495     


Arg Lys Lys Thr Lys Ile Arg Gly Gly Leu Pro Ala Phe Ser Glu Ile 
            500                 505                 510         


Ser Arg Arg Pro Thr Pro Gly Pro Leu Ala Gly Leu Val Pro Ser Phe 
        515                 520                 525             


Pro Pro Thr Thr 
    530         


<210>  1698
<211>  138
<212>  PRT
<213>  Homo Sapiens

<400>  1698

Lys Ile Tyr Glu Arg Cys Glu Leu Ala Ala Arg Leu Glu Arg Ala Gly 
1               5                   10                  15      


Leu Asn Gly Tyr Lys Gly Tyr Gly Val Gly Asp Trp Leu Cys Met Ala 
            20                  25                  30          


His Tyr Glu Ser Gly Phe Asp Thr Ala Phe Val Asp His Asn Pro Asp 
        35                  40                  45              


Gly Ser Ser Glu Tyr Gly Ile Phe Gln Leu Asn Ser Ala Trp Trp Cys 
    50                  55                  60                  


Asp Asn Gly Ile Thr Pro Thr Lys Asn Leu Cys His Met Asp Cys His 
65                  70                  75                  80  


Asp Leu Leu Asn Arg His Ile Leu Asp Asp Ile Arg Cys Ala Lys Gln 
                85                  90                  95      


Ile Val Ser Ser Gln Asn Gly Leu Ser Ala Trp Thr Ser Trp Arg Leu 
            100                 105                 110         


His Cys Ser Gly His Asp Leu Ser Glu Trp Leu Lys Gly Cys Asp Met 
        115                 120                 125             


His Val Lys Ile Asp Pro Lys Ile His Pro 
    130                 135             


<210>  1699
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  1699

Arg Pro Arg Thr Val Ile Pro Gly Ser Pro Thr Glu Ile Pro Phe Ser 
1               5                   10                  15      


Ser Lys Gln Glu Asp Met Ser Glu Leu Leu Asp Glu Ile Leu Val Gln 
            20                  25                  30          


Glu Ile Leu Asp Leu Asn Lys Thr Thr Pro Ser Glu Met Pro Ser Thr 
        35                  40                  45              


Ala Ser Thr Leu Ser Thr Pro Leu His Ala Gly Ile Asp Glu Asn Tyr 
    50                  55                  60                  


Gln Ala Gly Gly Ser Glu Asn Tyr His Glu Leu Leu Glu Asn Leu Gln 
65                  70                  75                  80  


Phe Ser Pro Gly Ile Glu Val Lys Ile Ser Asn Asp Glu Ala Asn Ala 
                85                  90                  95      


Asn Ala Asn Leu His Gly Asp Pro Ser Glu Asn Tyr Arg Gly Pro Gln 
            100                 105                 110         


Val Ser Pro Gly Ser Glu Lys Ser Val Ser Ser Lys Glu Lys Asn Ser 
        115                 120                 125             


Lys Asn Thr Gln Tyr Glu Asn Leu Ser Ile Leu Asp Gln Ile Leu Gln 
    130                 135                 140                 


Asn Ile Gly Arg Ser Ser Gly Asn Ile Phe His Lys Glu Gln Gln Arg 
145                 150                 155                 160 


Thr Ser Ala Gln Arg Arg Ser Gln Gly Ser Gln 
                165                 170     


<210>  1700
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  1700

Arg His Val Asn His Ser Ala Thr Glu Ala Leu Gly Glu Leu Arg Glu 
1               5                   10                  15      


Arg Ala Pro Gly Gln Gly Thr Asn Gly Phe Gln Leu Leu Arg His Ala 
            20                  25                  30          


Val Lys Arg Asp Leu Leu Pro Pro Arg Thr Pro Pro Tyr Gln Val His 
        35                  40                  45              


Ile Ser His Gln Glu Ala Arg Gly Pro Ser Phe Lys Ile Cys Val Gly 
    50                  55                  60                  


Phe Leu Gly Pro Arg Trp Ala Arg Gly Cys Ser Thr Gly Asn Glu Lys 
65                  70                  75                  80  


Tyr His Leu Pro Tyr Ala Ala Arg Asp Leu Gln Thr Phe Phe Leu Pro 
                85                  90                  95      


Phe Trp 
        


<210>  1701
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  1701

Arg His Val Asn His Ser Ala Thr Glu Ala Leu Gly Glu Leu Arg Glu 
1               5                   10                  15      


Arg Ala Pro Gly Gln Gly Thr Asn Gly Phe Gln Leu Leu Arg His Ala 
            20                  25                  30          


Val Lys Arg Asp Leu Leu Pro Pro Arg Thr Pro Pro Tyr Gln Val His 
        35                  40                  45              


Ile Ser His Arg Glu Ala Arg Gly Pro Ser Phe Arg Ile Cys Val Asp 
    50                  55                  60                  


Phe Leu Gly Pro Arg Trp Ala Arg Gly Cys Ser Thr Gly Asn 
65                  70                  75              


<210>  1702
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  1702

Ala Pro Gln Gln Glu Ala Leu Pro Asp Glu Thr Glu Val Val Glu Glu 
1               5                   10                  15      


Thr Val Ala Glu Val Thr Glu Val Ser Val Gly Ala Asn Pro Val Gln 
            20                  25                  30          


Val Glu Val Gly Glu Phe Asp Asp Gly Ala Glu Glu Thr Glu Glu Glu 
        35                  40                  45              


Val Val Ala Glu Asn Pro Cys Gln Asn His His Cys Lys His Gly Lys 
    50                  55                  60                  


Val Cys Glu Leu Asp Glu Asn Asn Thr Pro Met Cys Val Cys Gln Asp 
65                  70                  75                  80  


Pro Thr Ser Cys Pro Ala Pro Ile Gly Glu Phe Glu Lys Val Cys Ser 
                85                  90                  95      


Asn Asp Asn Lys Thr Phe Asp Ser Ser Cys His Phe Phe Ala Thr Lys 
            100                 105                 110         


Cys Thr Leu Glu Gly Thr Lys Lys Gly His Lys Leu His Leu Asp Tyr 
        115                 120                 125             


Ile Gly Pro Cys Lys Tyr Ile Pro Pro Cys Leu Asp Ser Glu Leu Thr 
    130                 135                 140                 


Glu Phe Pro Leu Arg Met Arg Asp Trp Leu Lys Asn Val Leu Val Thr 
145                 150                 155                 160 


Leu Tyr Glu Arg Asp Glu Asp Asn Asn Leu Leu Thr Glu Lys Gln Lys 
                165                 170                 175     


Leu Arg Val Lys Lys Ile His Glu Asn Glu Lys Arg Leu Glu Ala Gly 
            180                 185                 190         


Asp His Pro Val Glu Leu Leu Ala Arg Asp Phe Glu Lys Asn Tyr Asn 
        195                 200                 205             


Met Tyr Ile Phe Pro Val His Trp Gln Phe Gly Gln Leu Asp Gln His 
    210                 215                 220                 


Pro Ile Asp Gly Tyr Leu Ser His Thr Glu Leu Ala Pro Leu Arg Ala 
225                 230                 235                 240 


Pro Leu Ile Pro Met Glu His Cys Thr Thr Arg Phe Phe Glu Thr Cys 
                245                 250                 255     


Asp Leu Asp Asn Asp Lys Tyr Ile Ala Leu Asp Glu Trp Ala Gly Cys 
            260                 265                 270         


Phe Gly Ile Lys Gln Lys Asp Ile Asp Lys Asp Leu Val Ile 
        275                 280                 285     


<210>  1703
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  1703

Ile Asp Phe Pro Leu Pro Met Ala Ser Glu Arg Gly Gln Leu Asp Lys 
1               5                   10                  15      


Thr Ile Val Glu Cys Leu Lys Asn Val Asn Lys Cys Trp Phe Leu Ser 
            20                  25                  30          


Tyr Ile Lys Pro Ser Glu Pro Ile Cys Gly Ser Asp Gln Val Thr Tyr 
        35                  40                  45              


Ser Ser Asp Cys His Leu Cys Ser Lys Ile Leu Phe Glu Gly Leu Asn 
    50                  55                  60                  


Ile Thr Lys Leu Tyr Asp Gly Gln Cys Glu Asn Ser 
65                  70                  75      


<210>  1704
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  1704

Gly Val Asn Lys Ile Ala Glu Lys Ile Cys Gly Asp Leu Lys Asp Pro 
1               5                   10                  15      


Cys Lys Leu Asp Met Asn Phe Gly Ser Cys Tyr Glu Val His Phe Arg 
            20                  25                  30          


Tyr Phe Tyr Asn Arg Thr Ser Lys Arg Cys Glu Thr Phe Val Phe Ser 
        35                  40                  45              


Gly Cys Asn Gly Asn Leu Asn Asn Phe Lys Leu Lys Ile Glu Arg Glu 
    50                  55                  60                  


Val Ala Cys Val Ala Lys Tyr Lys Pro Pro Arg 
65                  70                  75  


<210>  1705
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  1705

Gln Pro Leu Gly Gly Glu Ser Ile Cys Ser Ala Arg Ala Leu Ala Lys 
1               5                   10                  15      


Tyr Ser Ile Thr Phe Thr Gly Lys Trp Ser Gln Thr Ala Phe Pro Lys 
            20                  25                  30          


Gln Tyr Pro Leu Phe Arg Pro Pro Ala Gln Trp Ser Ser Leu Leu Gly 
        35                  40                  45              


Ala Ala His Ser Ser Asp Tyr Ser Met Trp Arg Lys Asn Gln Tyr Val 
    50                  55                  60                  


Ser Asn Gly Leu Arg Asp Phe Ala Glu Arg Gly Glu Ala Trp Ala Leu 
65                  70                  75                  80  


Met Lys Glu Ile Glu Ala Ala Gly Glu Ala Leu Gln Ser Val His Glu 
                85                  90                  95      


Val Phe Ser Ala Pro Ala Val Pro Ser Gly Thr Gly Gln Thr Ser Ala 
            100                 105                 110         


Glu Leu Glu Val Gln Arg Arg His Ser Leu Val Ser Phe Val Val Arg 
        115                 120                 125             


Ile Val Pro Ser Pro Asp Trp Phe Val Gly Val Asp Ser Leu Asp Leu 
    130                 135                 140                 


Cys Asp Gly Asp Arg Trp Arg Glu Gln Ala Ala Leu Asp Leu Tyr Pro 
145                 150                 155                 160 


Tyr Asp Ala Gly Thr Asp Ser Gly Phe Thr Phe Ser Ser Pro Asn Phe 
                165                 170                 175     


Ala Thr Ile Pro Gln Asp Thr Val Thr Glu Ile Thr Ser Ser Ser Pro 
            180                 185                 190         


Ser His Pro Ala Asn Ser Phe Tyr Tyr Pro Arg Leu Lys Ala Leu Pro 
        195                 200                 205             


Pro Ile Ala Arg Val Thr Leu Val Arg Leu Arg Gln Ser Pro Arg Ala 
    210                 215                 220                 


Phe Ile Pro Pro Ala Pro Val Leu Pro Ser Arg Asp Asn Glu Ile Val 
225                 230                 235                 240 


Asp Ser Ala Ser Val Pro Glu Thr Pro Leu Asp Cys Glu Val Ser Leu 
                245                 250                 255     


Trp Ser Ser Trp Gly Leu Cys Gly Gly His Cys Gly Arg Leu Gly Thr 
            260                 265                 270         


Lys Ser Arg Thr Arg Tyr Val Arg Val Gln Pro Ala Asn Asn Gly Ser 
        275                 280                 285             


Pro Cys Pro Glu Leu Glu Glu Glu Ala Glu Cys Val Pro Asp Asn Cys 
    290                 295                 300                 


Val 
305 


<210>  1706
<211>  182
<212>  PRT
<213>  Homo Sapiens

<400>  1706

Phe Pro Val Tyr Asp Tyr Asp Pro Ser Ser Leu Arg Asp Ala Leu Ser 
1               5                   10                  15      


Ala Ser Val Val Lys Val Asn Ser Gln Ser Leu Ser Pro Tyr Leu Phe 
            20                  25                  30          


Arg Ala Phe Arg Ser Ser Leu Lys Arg Val Glu Val Leu Asp Glu Asn 
        35                  40                  45              


Asn Leu Val Met Asn Leu Glu Phe Ser Ile Arg Glu Thr Thr Cys Arg 
    50                  55                  60                  


Lys Asp Ser Gly Glu Asp Pro Ala Thr Cys Ala Phe Gln Arg Asp Tyr 
65                  70                  75                  80  


Tyr Val Ser Thr Ala Val Cys Arg Ser Thr Val Lys Val Ser Ala Gln 
                85                  90                  95      


Gln Val Gln Gly Val His Ala Arg Cys Ser Trp Ser Ser Ser Thr Ser 
            100                 105                 110         


Glu Ser Tyr Ser Ser Glu Glu Met Ile Phe Gly Asp Met Leu Gly Ser 
        115                 120                 125             


His Lys Trp Arg Asn Asn Tyr Leu Phe Gly Leu Ile Ser Asp Glu Ser 
    130                 135                 140                 


Ile Ser Glu Gln Phe Tyr Asp Arg Ser Leu Gly Ile Met Arg Arg Val 
145                 150                 155                 160 


Leu Pro Pro Gly Asn Arg Arg Tyr Pro Asn His Arg His Arg Ala Arg 
                165                 170                 175     


Ile Asn Thr Asp Phe Glu 
            180         


<210>  1707
<211>  82
<212>  PRT
<213>  Homo Sapiens

<400>  1707

Leu Ala Thr Glu Ala Gly Gln Lys Pro Ser Leu Arg Gly Leu Leu Asp 
1               5                   10                  15      


Val Gly Asn Ile Gln His Arg Ala Ala Arg Ala Arg Gly Leu Thr Arg 
            20                  25                  30          


Gly Val Ile Arg Val Ser Pro Gln Glu Arg Ser Gln Gln Asn Gln Ser 
        35                  40                  45              


Ala Pro Lys Gly Pro Thr Pro Ser Thr Arg Pro Lys Pro Arg Thr Leu 
    50                  55                  60                  


Gly Pro Gln Ala His Ser Leu Ala Leu Gln Ser Val Asp Leu Leu Phe 
65                  70                  75                  80  


Arg Pro 
        


<210>  1708
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  1708

Met Glu Ser Leu Ser Glu Leu Gln Asn Pro Leu Leu Pro Arg Ser Pro 
1               5                   10                  15      


Ala His Leu His Gly Pro Tyr Pro Tyr Pro Glu Thr Pro Pro Ser Trp 
            20                  25                  30          


Ser Cys Gln Glu Lys Leu Tyr Ser Tyr Leu Leu Gly Gly Ala Gly Pro 
        35                  40                  45              


Ala Gly Ala His Gln Leu Leu Asp Pro Gly Ser Leu Gln Leu Ala Val 
    50                  55                  60                  


Glu Ala Trp Tyr Arg Pro Ser Cys Leu Leu Gly Arg Asp Lys Val Lys 
65                  70                  75                  80  


Glu Pro Arg Ala Gly Ser Cys Glu Thr Ser Phe Thr Glu Asp Arg Glu 
                85                  90                  95      


Pro Gln Glu Gly Pro Pro Glu Gln Pro Thr Gly Pro Gly Gln Ala Ala 
            100                 105                 110         


Glu Asn Val Thr Ile Gln Thr Val Ser Tyr Gly Val Gln Glu Glu Leu 
        115                 120                 125             


Arg Asp Gln Glu Asp Asp Gln Glu Glu Glu Glu Ser Asp Ala Thr Ser 
    130                 135                 140                 


Thr Glu Ser Glu Ser Glu Asp Asn Phe Leu Thr Leu Pro Pro Arg Asp 
145                 150                 155                 160 


His Leu 
        


<210>  1709
<211>  83
<212>  PRT
<213>  Homo Sapiens

<400>  1709

Asn Trp Leu Val Lys Tyr Glu His Lys Leu Thr Leu Pro Glu Pro Gln 
1               5                   10                  15      


Gln Asp Glu Ile Leu Gln Arg Leu Leu Phe Ser Glu Met Lys Met Lys 
            20                  25                  30          


Val Leu Glu Asn Gln Met Phe Ile Ile Trp Asn Lys Met Asn His His 
        35                  40                  45              


Gly Arg Ser Ser Arg His Arg Asn Phe Pro Met Lys Lys His Arg Met 
    50                  55                  60                  


Arg Arg His Glu Ser Ile Cys Pro Thr Leu Ser Asp Cys Thr Ser Ser 
65                  70                  75                  80  


Ser Pro Ser 
            


<210>  1710
<211>  276
<212>  PRT
<213>  Homo Sapiens

<400>  1710

Asp Ser Glu Glu Asp Glu Glu His Thr Ile Ile Thr Asp Thr Glu Leu 
1               5                   10                  15      


Pro Pro Leu Lys Leu Met His Ser Phe Cys Ala Phe Lys Ala Asp Asp 
            20                  25                  30          


Gly Pro Cys Lys Ala Ile Met Lys Arg Phe Phe Phe Asn Ile Phe Thr 
        35                  40                  45              


Arg Gln Cys Glu Glu Phe Ile Tyr Gly Gly Cys Glu Gly Asn Gln Asn 
    50                  55                  60                  


Arg Phe Glu Ser Leu Glu Glu Cys Lys Lys Met Cys Thr Arg Asp Asn 
65                  70                  75                  80  


Ala Asn Arg Ile Ile Lys Thr Thr Leu Gln Gln Glu Lys Pro Asp Phe 
                85                  90                  95      


Cys Phe Leu Glu Glu Asp Pro Gly Ile Cys Arg Gly Tyr Ile Thr Arg 
            100                 105                 110         


Tyr Phe Tyr Asn Asn Gln Thr Lys Gln Cys Glu Arg Phe Lys Tyr Gly 
        115                 120                 125             


Gly Cys Leu Gly Asn Met Asn Asn Phe Glu Thr Leu Glu Glu Cys Lys 
    130                 135                 140                 


Asn Ile Cys Glu Asp Gly Pro Asn Gly Phe Gln Val Asp Asn Tyr Gly 
145                 150                 155                 160 


Thr Gln Leu Asn Ala Val Asn Asn Ser Leu Thr Pro Gln Ser Thr Lys 
                165                 170                 175     


Val Pro Ser Leu Phe Glu Phe His Gly Pro Ser Trp Cys Leu Thr Pro 
            180                 185                 190         


Ala Asp Arg Gly Leu Cys Arg Ala Asn Glu Asn Arg Phe Tyr Tyr Asn 
        195                 200                 205             


Ser Val Ile Gly Lys Cys Arg Pro Phe Lys Tyr Ser Gly Cys Gly Gly 
    210                 215                 220                 


Asn Glu Asn Asn Phe Thr Ser Lys Gln Glu Cys Leu Arg Ala Cys Lys 
225                 230                 235                 240 


Lys Gly Phe Ile Gln Arg Ile Ser Lys Gly Gly Leu Ile Lys Thr Lys 
                245                 250                 255     


Arg Lys Arg Lys Lys Gln Arg Val Lys Ile Ala Tyr Glu Glu Ile Phe 
            260                 265                 270         


Val Lys Asn Met 
        275     


<210>  1711
<211>  268
<212>  PRT
<213>  Homo Sapiens

<400>  1711

Met Gly Glu Ser Ala Ala Ala Thr Ala Ser Leu Phe Gln Arg Arg Arg 
1               5                   10                  15      


Arg Gly Arg Gly Gly Arg Val Thr Phe Pro Gly Gly Leu Lys Gly Ser 
            20                  25                  30          


Ala Arg Phe Leu Ser Phe Gly Pro Pro Phe Pro Ala Pro Pro Ala Pro 
        35                  40                  45              


Pro Phe Pro Ala Ala Pro Gly Pro Trp Leu Arg Arg Pro Leu Phe Ser 
    50                  55                  60                  


Leu Lys Leu Ser Asp Thr Glu Asp Val Phe Pro Arg Arg Ala Gly Pro 
65                  70                  75                  80  


Leu Glu Val Pro Ala Asp Ser Arg Val Phe Val Gln Ala Ala Leu Ala 
                85                  90                  95      


Arg Pro Ser Pro Arg Trp Gly Leu Ala Leu His Arg Cys Ser Val Thr 
            100                 105                 110         


Pro Ser Ser Arg Pro Ala Pro Gly Pro Ala Leu Ala Leu Leu Arg Glu 
        115                 120                 125             


Gly Cys Pro Ala Asp Thr Ser Val Ala Phe Pro Pro Pro Pro Pro Pro 
    130                 135                 140                 


Ser Pro Gly Ala Ala Arg Pro Ala Arg Phe Ser Phe Arg Leu Arg Pro 
145                 150                 155                 160 


Val Phe Asn Ala Ser Val Gln Phe Leu His Cys Gln Leu Ser Arg Cys 
                165                 170                 175     


Arg Arg Leu Arg Gly Val Arg Arg Ala Pro Ala Pro Leu Thr Pro Pro 
            180                 185                 190         


Pro Pro Pro Pro Pro Ser Arg Cys Leu Pro Gln Asp Glu Ala Cys Ala 
        195                 200                 205             


Asp Thr Gly Ser Gly Ser Ala Glu Gly Leu Ala Ala Asp Gly Pro His 
    210                 215                 220                 


Leu His Thr Leu Thr Gln Pro Ile Val Val Thr Val Pro Arg Pro Pro 
225                 230                 235                 240 


Pro Arg Pro Pro Lys Ser Val Pro Gly Arg Ala Val Arg Pro Glu Pro 
                245                 250                 255     


Pro Ala Pro Ala Pro Ala Ala Leu Glu Pro Ala Pro 
            260                 265             


<210>  1712
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  1712

Leu Leu Asp Val Trp Tyr Leu Val Arg Leu Pro Cys Ala Val Leu Arg 
1               5                   10                  15      


Ala Arg Leu Leu Gln Pro Arg Val Arg Asp Leu Leu Ala Glu Gln Arg 
            20                  25                  30          


Phe Pro Gly Arg Val Leu Pro Ser Asp Leu Asp Leu Leu Leu His Met 
        35                  40                  45              


Asn Asn Ala Arg Tyr Leu Arg Glu Ala Asp Phe Ala Arg Val Ala His 
    50                  55                  60                  


Leu Thr Arg Cys Gly Val Leu Gly Ala Leu Arg Glu Leu Arg Ala His 
65                  70                  75                  80  


Thr Val Leu Ala Ala Ser Cys Ala Arg His Arg Arg Ser Leu Arg Leu 
                85                  90                  95      


Leu Glu Pro Phe Glu Val Arg Thr Arg Leu Leu Gly Trp Asp Asp Arg 
            100                 105                 110         


Ala Phe Tyr Leu Glu Ala Arg Phe Val Ser Leu Arg Asp Gly Phe Val 
        115                 120                 125             


Cys Ala Leu Leu Arg Phe Arg Gln His Leu Leu Gly Thr Ser Pro Glu 
    130                 135                 140                 


Arg Val Val Gln His Leu Cys Gln Arg Arg Val Glu Pro Pro Glu Leu 
145                 150                 155                 160 


Pro Ala Asp Leu Gln His Trp Ile Ser Tyr Asn Glu Ala Ser Ser Gln 
                165                 170                 175     


Leu Leu Arg Met Glu Ser Gly Leu Ser Asp Val Thr Lys Asp Gln 
            180                 185                 190     


<210>  1713
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  1713

Met Trp Tyr Val Ser Thr Arg Gly Val Ala Pro Arg Val Asn Phe Glu 
1               5                   10                  15      


Gly Ala Leu Phe Ser Gly Tyr Ala Pro Asp Gly Gly Leu Phe Met Pro 
            20                  25                  30          


Glu Glu Leu Pro Gln Leu Asp Arg Gly Thr Leu Cys Gln Trp Ser Thr 
        35                  40                  45              


Leu Ser Tyr Pro Gly Leu Val Lys Glu Leu Cys Ala Leu Phe Ile Gly 
    50                  55                  60                  


Ser Glu Leu Leu Pro Lys Asp Glu Leu Asn Asp Leu Ile Asp Arg Ala 
65                  70                  75                  80  


Phe Ser Arg Phe Arg His Arg Glu Val Val His Leu Ser Arg Leu Arg 
                85                  90                  95      


Asn Gly Leu Asn Val Leu Glu Leu Trp His Gly Val Thr Tyr Ala Phe 
            100                 105                 110         


Lys Asp Leu Ser Leu Ser Cys Thr Thr Gln Phe Leu Gln Tyr Phe Leu 
        115                 120                 125             


Glu Lys Arg Glu Lys His Val Thr Val Val Val Gly Thr Ser Gly Asp 
    130                 135                 140                 


Thr Gly Ser Ala Ala Ile Glu Ser Val Gln Gly Ala Lys Asn Met Asp 
145                 150                 155                 160 


Ile Ile Val Leu Leu Pro Lys Gly His Cys Thr Lys Ile Gln Glu Leu 
                165                 170                 175     


Gln Met Thr Thr Val Leu Lys Gln Asn Val His Val Phe Gly Val Glu 
            180                 185                 190         


Gly Asn Ser Asp Glu Leu Asp Glu Pro Ile Lys Thr Val Phe Ala Asp 
        195                 200                 205             


Val Ala Phe Val Lys Lys His Asn Leu Met Ser Leu Asn Ser Ile Asn 
    210                 215                 220                 


Trp Ser Arg Val Leu Val Gln Met Ala His His Phe Phe Ala Tyr Phe 
225                 230                 235                 240 


Gln Cys Thr Pro Ser Leu Asp Thr His Pro Leu Pro Leu Val Glu Val 
                245                 250                 255     


Val Val Pro Thr Gly Ala Ala Gly Asn Leu Ala Ala Gly Tyr Ile Ala 
            260                 265                 270         


Gln Lys Ile Gly Leu Pro Ile Arg Leu Val Val Ala Val Asn Arg Asn 
        275                 280                 285             


Asp Ile Ile His Arg Thr Val Gln Gln Gly Asp Phe Ser Leu Ser Glu 
    290                 295                 300                 


Ala Val Lys Ser Thr Leu Ala Ser Ala Met Asp Ile Gln Val Pro Tyr 
305                 310                 315                 320 


Asn Met Glu Arg Val Phe Trp Leu Leu Ser Gly Ser Asp Ser Gln Val 
                325                 330                 335     


Thr Arg Ala Leu Met Glu Gln Phe Glu Arg Thr Gln Ser Val Asn Leu 
            340                 345                 350         


Pro Lys Glu Leu His Ser Lys Leu Ser Glu Ala Val Thr Ser Val Ser 
        355                 360                 365             


Val Ser Asp Glu Ala Ile Thr Gln Thr Met Gly Arg Cys Trp Asp Glu 
    370                 375                 380                 


Asn Gln Tyr Leu Leu Cys Pro His Ser Ala Val Ala Val Asn Tyr His 
385                 390                 395                 400 


Tyr Gln Gln Ile Asp Arg Gln Gln Pro Ser Thr Pro Arg Cys Cys Leu 
                405                 410                 415     


Ala Pro Ala Ser Ala Ala Lys Phe Pro Glu Ala Val Leu Ala Ala Gly 
            420                 425                 430         


Leu Thr Pro Glu Thr Pro Ala Glu Ile Val Ala Leu Glu His Lys Glu 
        435                 440                 445             


Thr Arg Cys Thr Leu Met Arg Arg Gly Asp Asn Trp Met Leu Met Leu 
    450                 455                 460                 


Arg Asp Thr Ile Glu Asp Leu Ser Arg Gln Trp Arg Ser His Ala Leu 
465                 470                 475                 480 


Asn Thr Ser Gln 
                


<210>  1714
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  1714

Ser Pro Ala Pro Pro Ala Cys Asp Leu Arg Val Leu Ser Lys Leu Leu 
1               5                   10                  15      


Arg Asp Ser His Val Leu His Ser Arg Leu Ser Gln Cys Pro Glu Val 
            20                  25                  30          


His Pro Leu Pro Thr Pro Val Leu Leu Pro Ala Val Asp Phe Ser Leu 
        35                  40                  45              


Gly Glu Trp Lys Thr Gln Met Glu Glu Thr Lys Ala Gln Asp Ile Leu 
    50                  55                  60                  


Gly Ala Val Thr Leu Leu Leu Glu Gly Val Met Ala Ala Arg Gly Gln 
65                  70                  75                  80  


Leu Gly Pro Thr Cys Leu Ser Ser Leu Leu Gly Gln Leu Ser Gly Gln 
                85                  90                  95      


Val Arg Leu Leu Leu Gly Ala Leu Gln Ser Leu Leu Gly Thr Gln Leu 
            100                 105                 110         


Pro Pro Gln Gly Arg Thr Thr Ala His Lys Asp Pro Asn Ala Ile Phe 
        115                 120                 125             


Leu Ser Phe Gln His Leu Leu Arg Gly Lys Val Arg Phe Leu Met Leu 
    130                 135                 140                 


Val Gly Gly Ser Thr Leu Cys Val Arg Arg Ala Pro Pro Thr Thr Ala 
145                 150                 155                 160 


Val Pro Ser Arg Thr Ser Leu Val Leu Thr Leu Asn Glu Leu Pro Asn 
                165                 170                 175     


Arg Thr Ser Gly Leu Leu Glu Thr Asn Phe Thr Ala Ser Ala Arg Thr 
            180                 185                 190         


Thr Gly Ser Gly Leu Leu Lys Trp Gln Gln Gly Phe Arg Ala Lys Ile 
        195                 200                 205             


Pro Gly Leu Leu Asn Gln Thr Ser Arg Ser Leu Asp Gln Ile Pro Gly 
    210                 215                 220                 


Tyr Leu Asn Arg Ile His Glu Leu Leu Asn Gly Thr Arg Gly Leu Phe 
225                 230                 235                 240 


Pro Gly Pro Ser Arg Arg Thr Leu Gly Ala Pro Asp Ile Ser Ser Gly 
                245                 250                 255     


Thr Ser Asp Thr Gly Ser Leu Pro Pro Asn Leu Gln Pro Gly Tyr Ser 
            260                 265                 270         


Pro Ser Pro Thr His Pro Pro Thr Gly Gln Tyr Thr Leu Phe Pro Leu 
        275                 280                 285             


Pro Pro Thr Leu Pro Thr Pro Val Val Gln Leu His Pro Leu Leu Pro 
    290                 295                 300                 


Asp Pro Ser Ala Pro Thr Pro Thr Pro Thr Ser Pro Leu Leu Asn Thr 
305                 310                 315                 320 


Ser Tyr Thr His Ser Gln Asn Leu Ser Gln Glu Gly 
                325                 330         


<210>  1715
<211>  274
<212>  PRT
<213>  Homo Sapiens

<400>  1715

Ala Glu Val Phe Gly Asn Ser Ser Glu Gly Leu Ile Glu Phe Ser Val 
1               5                   10                  15      


Gly Lys Phe Arg Tyr Phe Glu Leu Asn Arg Pro Phe Pro Glu Glu Ala 
            20                  25                  30          


Ile Leu His Asp Ile Ser Ser Asn Val Thr Phe Leu Ile Phe Gln Ile 
        35                  40                  45              


His Ser Gln Tyr Gln Asn Thr Thr Val Ser Phe Ser Pro Thr Leu Leu 
    50                  55                  60                  


Ser Asn Ser Ser Glu Thr Gly Thr Ala Ser Gly Leu Val Phe Ile Leu 
65                  70                  75                  80  


Arg Pro Glu Gln Ser Thr Cys Thr Trp Tyr Leu Gly Thr Ser Gly Ile 
                85                  90                  95      


Gln Pro Val Gln Asn Met Ala Ile Leu Leu Ser Tyr Ser Glu Arg Asp 
            100                 105                 110         


Pro Val Pro Gly Gly Cys Asn Leu Glu Phe Asp Leu Asp Ile Asp Pro 
        115                 120                 125             


Asn Ile Tyr Leu Glu Tyr Asn Phe Phe Glu Thr Thr Ile Lys Phe Ala 
    130                 135                 140                 


Pro Ala Asn Leu Gly Tyr Ala Arg Gly Val Asp Pro Pro Pro Cys Asp 
145                 150                 155                 160 


Ala Gly Thr Asp Gln Asp Ser Arg Trp Arg Leu Gln Tyr Asp Val Tyr 
                165                 170                 175     


Gln Tyr Phe Leu Pro Glu Asn Asp Leu Thr Glu Glu Met Leu Leu Lys 
            180                 185                 190         


His Leu Gln Arg Met Val Ser Val Pro Gln Val Lys Ala Ser Ala Leu 
        195                 200                 205             


Lys Val Val Thr Leu Thr Ala Asn Asp Lys Thr Ser Val Ser Phe Ser 
    210                 215                 220                 


Ser Leu Pro Gly Gln Gly Val Ile Tyr Asn Val Ile Val Trp Asp Pro 
225                 230                 235                 240 


Phe Leu Asn Thr Ser Ala Ala Tyr Ile Pro Ala His Thr Tyr Ala Cys 
                245                 250                 255     


Ser Phe Glu Ala Gly Glu Gly Ser Cys Ala Ser Leu Gly Arg Val Ser 
            260                 265                 270         


Ser Lys 
        


<210>  1716
<211>  195
<212>  PRT
<213>  Homo Sapiens

<400>  1716

Asp Glu His Glu His Thr Tyr Gln Asp Lys Glu Glu Val Val Leu Trp 
1               5                   10                  15      


Met Asn Thr Val Gly Pro Tyr His Asn Arg Gln Glu Thr Tyr Lys Tyr 
            20                  25                  30          


Phe Ser Leu Pro Phe Cys Val Gly Ser Lys Lys Ser Ile Ser His Tyr 
        35                  40                  45              


His Glu Thr Leu Gly Glu Ala Leu Gln Gly Val Glu Leu Glu Phe Ser 
    50                  55                  60                  


Gly Leu Asp Ile Lys Phe Lys Asp Asp Val Met Pro Ala Thr Tyr Cys 
65                  70                  75                  80  


Glu Ile Asp Leu Asp Lys Glu Lys Arg Asp Ala Phe Val Tyr Ala Ile 
                85                  90                  95      


Lys Asn His Tyr Trp Tyr Gln Met Tyr Ile Asp Asp Leu Pro Ile Trp 
            100                 105                 110         


Gly Ile Val Gly Glu Ala Asp Glu Asn Gly Glu Asp Tyr Tyr Leu Trp 
        115                 120                 125             


Thr Tyr Lys Lys Leu Glu Ile Gly Phe Asn Gly Asn Arg Ile Val Asp 
    130                 135                 140                 


Val Asn Leu Thr Ser Glu Gly Lys Val Lys Leu Val Pro Asn Thr Lys 
145                 150                 155                 160 


Ile Gln Met Ser Tyr Ser Val Lys Trp Lys Lys Ser Asp Val Lys Phe 
                165                 170                 175     


Glu Asp Arg Phe Asp Lys Tyr Leu Asp Pro Ser Phe Phe Gln His Arg 
            180                 185                 190         


Ile His Trp 
        195 


<210>  1717
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  1717

Arg Ser Val Pro Leu Lys Ala Thr Phe Leu Glu Asp Val Ala Gly Ser 
1               5                   10                  15      


Gly Glu Ala Glu Gly Ser Ser Ala Ser Ser Pro Ser Leu Pro Pro Pro 
            20                  25                  30          


Trp Thr Pro Ala Leu Ser Pro Thr Ser Met Gly Pro Gln Pro Ile Thr 
        35                  40                  45              


Leu Gly Gly Pro Ser Pro Pro Thr Asn Phe Leu Asp Gly Ile Val Asp 
    50                  55                  60                  


Phe Phe Arg Gln Tyr Val Met 
65                  70      


<210>  1718
<211>  135
<212>  PRT
<213>  Homo Sapiens

<400>  1718

Met Gln Pro Pro Pro Pro Gly Pro Leu Gly Asp Cys Leu Arg Asp Trp 
1               5                   10                  15      


Glu Asp Leu Gln Gln Asp Phe Gln Asn Ile Gln Glu Thr His Arg Leu 
            20                  25                  30          


Tyr Arg Leu Lys Leu Glu Glu Leu Thr Lys Leu Gln Asn Asn Cys Thr 
        35                  40                  45              


Ser Ser Ile Thr Arg Gln Lys Lys Arg Leu Gln Glu Leu Ala Leu Ala 
    50                  55                  60                  


Leu Lys Lys Cys Lys Pro Ser Leu Pro Ala Glu Ala Glu Gly Ala Ala 
65                  70                  75                  80  


Gln Glu Leu Glu Asn Gln Met Lys Glu Arg Gln Gly Leu Phe Phe Asp 
                85                  90                  95      


Met Glu Ala Tyr Leu Pro Lys Lys Asn Gly Leu Tyr Leu Ser Leu Val 
            100                 105                 110         


Leu Gly Asn Val Asn Val Thr Leu Leu Ser Lys Gln Ala Lys Phe Ala 
        115                 120                 125             


Tyr Lys Asp Glu Tyr Glu Lys 
    130                 135 


<210>  1719
<211>  186
<212>  PRT
<213>  Homo Sapiens

<400>  1719

Lys Thr Pro Lys Glu Arg Thr Leu Glu Leu Ser Cys Leu Glu Val Cys 
1               5                   10                  15      


Leu Gln Ser Asn Phe Thr Tyr Ser Leu Ser Ser Leu Asn Phe Ser Phe 
            20                  25                  30          


Val Thr Phe Leu Gln Pro Val Arg Glu Thr Gln Ile Ile Met Arg Ile 
        35                  40                  45              


Phe Leu Asn Pro Ser Asn Phe Arg Asn Phe Thr Arg Thr Cys Gln Asp 
    50                  55                  60                  


Ile Thr Gly Glu Phe Lys Met Cys Ser Ser Cys Leu Val Cys Glu Ser 
65                  70                  75                  80  


Lys Gly Asn Met Asp Phe Ile Ser Gln Glu Gln Thr Ser Lys Val Leu 
                85                  90                  95      


Ile Arg Arg Gly Ser Met Glu Val Lys Ala Asn Asp Phe His Ser Pro 
            100                 105                 110         


Cys Gln His Phe Asn Phe Ser Val Ala Pro Leu Val Asp His Leu Glu 
        115                 120                 125             


Glu Tyr Asn Thr Thr Cys His Leu Lys Asn His Thr Gly Arg Ser Thr 
    130                 135                 140                 


Ile Met Glu Asp Glu Pro Ser Lys Glu Lys Ser Ile Asn Tyr Thr Cys 
145                 150                 155                 160 


Arg Ile Met Glu Tyr Pro Asn Asp Cys Ile His Ile Ser Leu His Leu 
                165                 170                 175     


Glu Met Asp Ile Lys Asn Ile Thr Cys Ser 
            180                 185     


<210>  1720
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  1720

Gly Ala Ala Asp Ala Pro Gly Leu Leu Gly Val Pro Ser Asn Ala Ser 
1               5                   10                  15      


Val Asn Ala Ser Ser Ala Asp Glu Pro Ile Ala Pro Arg Leu Leu Ala 
            20                  25                  30          


Ser Ala Ala Pro Gly Pro Pro Glu Arg Pro Gly Pro Glu Glu Ala Ala 
        35                  40                  45              


Ala Ala Ala Ala Pro Cys Asn Ile Ser Val Gln Arg Gln Met Leu Ser 
    50                  55                  60                  


Ser Leu Leu Val Arg Trp Gly Arg Pro Arg Gly Phe Gln Cys Asp Leu 
65                  70                  75                  80  


Leu Leu Phe Ser Thr Asn Ala His Gly Arg Ala Phe Phe Ala Ala Ala 
                85                  90                  95      


Phe His Arg Val Gly Pro Pro Leu Leu Ile Glu His Leu Gly Leu Ala 
            100                 105                 110         


Ala Gly Gly Ala Gln Gln Asp Leu Arg Leu Cys Val Gly Cys Gly Trp 
        115                 120                 125             


Val Arg Gly Arg Arg Thr Gly Arg Leu Arg Pro Ala Ala Ala Pro Ser 
    130                 135                 140                 


Ala Ala Ala Ala Thr Ala Gly Ala Pro Thr Ala Leu Pro Ala Tyr Pro 
145                 150                 155                 160 


Ala Ala Glu Pro Pro Gly Pro Leu Trp Leu Gln Gly Glu Pro Leu His 
                165                 170                 175     


Phe Cys Cys Leu Asp Phe Ser Leu Glu Glu Leu Gln Gly Glu Pro Gly 
            180                 185                 190         


Trp Arg Leu Asn Arg Lys Pro Ile Glu Ser Thr Leu Val Ala Cys Phe 
        195                 200                 205             


Met Thr 
    210 


<210>  1721
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  1721

Ile Phe Thr Asp His Trp Tyr Glu Thr Asp Pro Arg Arg His Lys Glu 
1               5                   10                  15      


Ser Cys Glu Arg Ser Arg Ala Gly Ala Asp Pro Pro Asp Gln Lys Asn 
            20                  25                  30          


Arg Leu Met Pro Leu Ser His Leu Pro Leu Arg Asp Ser Pro Pro Leu 
        35                  40                  45              


Gly Arg Arg Leu Leu Pro Gly Gly Pro Gly Arg Ala Asp Pro Glu Ser 
    50                  55                  60                  


Trp Arg Ser Leu Leu Gly Leu Gly Gly Leu Asp Ala Glu Cys Gly Arg 
65                  70                  75                  80  


Pro Leu Phe Ala Thr Tyr Ser Gly Leu Trp Arg Lys Cys Tyr Phe Leu 
                85                  90                  95      


Gly Ile Asp Arg Asp Ile Asp Thr Leu Ile Leu Lys Gly Ile Ala Gln 
            100                 105                 110         


Arg Cys Thr Ala Ile Lys Tyr His Phe Ser Gln Pro Ile Arg Leu Arg 
        115                 120                 125             


Asn Ile Pro Phe Asn Leu Thr Lys Thr Ile Gln Gln Asp Glu Trp His 
    130                 135                 140                 


Leu Leu His Leu Arg Arg Ile Thr Ala Gly 
145                 150                 


<210>  1722
<211>  148
<212>  PRT
<213>  Homo Sapiens

<400>  1722

Val Ala Ile Cys Ser Asp His Trp Tyr Glu Thr Asp Ala Arg Lys His 
1               5                   10                  15      


Arg Asp Arg Cys Lys Ala Phe Asn Thr Arg Arg Val Asp Pro Gly Phe 
            20                  25                  30          


Ile Tyr Asn Asn Asn Asn Asn Leu Pro Leu Arg Ala Ser Arg Ser Arg 
        35                  40                  45              


Leu Asp Arg Trp Glu Gly Lys Leu Leu Arg Ala Arg Asn Arg Arg Gln 
    50                  55                  60                  


Leu Phe Ala Met Ser Pro Ala Asp Glu Cys Ser Arg Gln Tyr Asn Ser 
65                  70                  75                  80  


Thr Asn Met Gly Leu Trp Arg Lys Cys His Arg Gln Gly Phe Asp Pro 
                85                  90                  95      


Glu Ile Ala Ala Leu Ile Arg Lys Gly Glu Ile Glu Arg Cys Thr Tyr 
            100                 105                 110         


Ile Lys Tyr His Tyr Ser Ser Ala Thr Ile Pro Arg Asn Leu Thr Phe 
        115                 120                 125             


Asn Ile Thr Lys Thr Ile Arg Gln Asp Glu Trp His Ala Leu His Leu 
    130                 135                 140                 


Arg Arg Met Thr 
145             


<210>  1723
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  1723

Tyr Arg Thr Ile Thr Asp Phe Arg Glu Lys Leu Lys His Pro Val Met 
1               5                   10                  15      


Ser Val Ser Tyr Lys Glu Val Asp Arg Tyr Asp Ala Pro Gly Ile Ala 
            20                  25                  30          


Leu Tyr Pro Gly Gln Ala Gln Leu Leu Ser Cys Lys His His Tyr Glu 
        35                  40                  45              


Val Ile Pro Pro Leu Thr Ser Pro Gly Gln Pro Gly Asp Met Asn Cys 
    50                  55                  60                  


Thr Thr Gln Arg Ile Asn Tyr Thr Asp Pro Phe Ser Asn Gln Thr Val 
65                  70                  75                  80  


Lys Ser Ala Leu Ile Val Gln Gly Pro Arg Glu Val Lys Lys Arg Glu 
                85                  90                  95      


Leu Val Phe Leu Gln Phe Arg Leu Asn Lys Ser Ser Glu Asp Phe Ser 
            100                 105                 110         


Ala Ile Asp Tyr Leu Leu Phe Ser Ser Phe Gln Glu Phe Leu Gln Ser 
        115                 120                 125             


Pro Asn Arg Val Gly Phe Met Gln Ala Cys Glu Ser Ala Tyr Ser Ser 
    130                 135                 140                 


Trp Lys Phe Ser Gly Gly Phe Arg Thr Trp Val Lys Met Ser Leu Val 
145                 150                 155                 160 


Lys Thr Lys Glu Glu Asp Gly Arg Glu Ala Val Glu Phe Arg Gln Glu 
                165                 170                 175     


Thr Ser Val Val Asn Tyr Ile Asp Gln Arg Pro Ala Ala Lys Lys Ser 
            180                 185                 190         


Ala Gln Leu Phe Phe Val Val Phe Glu Trp Lys Asp Pro Phe Ile Gln 
        195                 200                 205             


Lys Val Gln Asp Ile Val Thr Ala 
    210                 215     


<210>  1724
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  1724

Ser Phe Leu Leu Thr His Arg Thr Gly Leu Arg Ser Pro Asp Ile Pro 
1               5                   10                  15      


Gln Asp Trp Val Ser Phe Leu Arg Ser Phe Gly Gln Leu Thr Leu Cys 
            20                  25                  30          


Pro Arg Asn Gly Thr Val Thr Gly Lys Trp Arg Gly Ser His Val Val 
        35                  40                  45              


Gly Leu Leu Thr Thr Leu Asn Phe Gly Asp Gly Pro Asp Arg Asn Lys 
    50                  55                  60                  


Thr Arg Thr Phe Gln Ala Thr Val Leu Gly Ser Gln Met Gly Leu Lys 
65                  70                  75                  80  


Gly Ser Ser Ala Gly Gln Leu Val Leu Ile Thr Ala Arg Val Thr Thr 
                85                  90                  95      


Glu Arg Thr Ala Gly Thr Cys Leu Tyr Phe Ser Ala Val Pro Gly Ile 
            100                 105                 110         


Leu Pro Ser Ser Gln Pro Pro Ile Ser Cys Ser Glu Glu Gly Ala Gly 
        115                 120                 125             


Asn Ala Thr Leu Ser Pro Arg Met Gly Glu Glu Cys Val Ser Val Trp 
    130                 135                 140                 


Ser His Glu Gly Leu Val Leu Thr Lys Leu Leu Thr Ser Glu Glu Leu 
145                 150                 155                 160 


Ala Leu Cys Gly Ser Arg 
                165     


<210>  1725
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  1725

Asp Tyr Trp Tyr Ile Leu Glu Val Ala Asp Ala Gly Asn Gly Ser Ala 
1               5                   10                  15      


Trp Pro Gly Arg Ala Glu Leu Leu Ser Ser His Ser Gly Leu Trp Arg 
            20                  25                  30          


Ile Cys Glu Gly Gln Asn Gly Cys Ile Pro Leu Val Asp Pro Phe Ala 
        35                  40                  45              


Ser Glu Ser Leu Asp Val Ser Thr Ser Val Gln His Leu Ile Leu Leu 
    50                  55                  60                  


His Arg Ala 
65          


<210>  1726
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1726

Asn Lys Ser Ser Glu Asp Ile Arg Cys Lys Cys Ile Cys Pro Pro Tyr 
1               5                   10                  15      


Arg Asn Ile Ser Gly His Ile Tyr Asn Gln Asn Val Ser Gln Lys Asp 
            20                  25                  30          


Cys Asn Cys Leu His Val Val Glu Pro Met Pro Val Pro Gly His Asp 
        35                  40                  45              


Val Glu Ala Tyr Cys Leu Leu Cys Glu Cys Arg Tyr Glu Glu Arg Ser 
    50                  55                  60                  


Thr Thr Thr Ile Lys 
65                  


<210>  1727
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1727

Met Asp Ser Pro Ser Leu Arg Glu Leu Gln Gln Pro Leu Leu Glu Gly 
1               5                   10                  15      


Thr Glu Cys Glu Thr Pro Ala Gln Lys Pro Gly Arg His Glu Leu Gly 
            20                  25                  30          


Ser Pro Leu Arg Glu Ile Ala Phe Ala Glu Ser Leu Arg Gly Leu Gln 
        35                  40                  45              


Phe Leu Ser Pro Pro Leu Pro Ser Val Ser Ala Gly Leu Gly Glu Pro 
    50                  55                  60                  


Arg Pro Pro Asp Val Glu Asp Met Ser Ser Ser Asp Ser Asp Ser Asp 
65                  70                  75                  80  


Trp Asp Gly Gly Ser Arg Leu Ser Pro Phe Leu Pro His Asp His Leu 
                85                  90                  95      


Gly 
    


<210>  1728
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  1728

Ser Tyr Val Pro Ser Val Ala Pro Thr Ala Ala His Ser Val Arg Val 
1               5                   10                  15      


Pro His Ser Ala Gly His Cys Gly Gln Arg Val Leu Ala Cys Ser Leu 
            20                  25                  30          


Pro Gln Val Phe Leu Lys Pro Trp Ile Phe Val Glu His Phe Ser Ser 
        35                  40                  45              


Trp Leu Ser Leu Glu Leu Phe Ser Phe Leu Arg Tyr Leu Gly Thr Leu 
    50                  55                  60                  


Leu Cys Ala Cys Gly His Arg Leu Arg Glu 
65                  70                  


<210>  1729
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  1729

Glu Asp Asp Lys Ser Phe Tyr Tyr Leu Ala Ser Phe Lys Val Thr Asn 
1               5                   10                  15      


Ile Lys Tyr Lys Glu Asn Tyr Gly Ile Arg Ser Ser Arg Glu Phe Ile 
            20                  25                  30          


Glu Arg Ser His Gln Ile Glu Arg Met Met Ser Arg Ile Phe Arg His 
        35                  40                  45              


Ser Ser Val Gly Gly Arg Phe Ile Lys Ser His Val Ile Lys Leu Ser 
    50                  55                  60                  


Pro Asp Glu Gln Gly Val Asp Ile Leu Ile Val Leu Ile Phe Arg Tyr 
65                  70                  75                  80  


Pro Ser Thr Asp Ser Ala Glu Gln Ile Lys Lys Lys Ile Glu Lys Ala 
                85                  90                  95      


Leu Tyr Gln Ser Leu Lys Thr Lys Gln Leu Ser Leu Thr Ile Asn Lys 
            100                 105                 110         


Pro Ser Phe Arg Leu Thr Pro Ile Asp Ser Lys Lys Met Arg Asn Leu 
        115                 120                 125             


Leu Asn Ser Arg Cys Gly Ile Arg Met Thr Ser Ser Asn Met Pro Leu 
    130                 135                 140                 


Pro Ala Ser Ser Ser Thr Gln Arg Ile Val Gln Gly Arg Glu Thr Ala 
145                 150                 155                 160 


Met Glu Gly Glu Trp Pro Trp Gln Ala Ser Leu Gln Leu Ile Gly Ser 
                165                 170                 175     


Gly His Gln Cys Gly Ala Ser Leu Ile Ser Asn Thr Trp Leu Leu Thr 
            180                 185                 190         


Ala Ala His Cys Phe Trp Lys Asn Lys Asp Pro Thr Gln Trp Ile Ala 
        195                 200                 205             


Thr Phe Gly Ala Thr Ile Thr Pro Pro Ala Val Lys Arg Asn Val Arg 
    210                 215                 220                 


Lys Ile Ile Leu His Glu Asn Tyr His Arg Glu Thr Asn Glu Asn Asp 
225                 230                 235                 240 


Ile Ala Leu Val Gln Leu Ser Thr Gly Val Glu Phe Ser Asn Ile Val 
                245                 250                 255     


Gln Arg Val Cys Leu Pro Asp Ser Ser Ile Lys Leu Pro Pro Lys Thr 
            260                 265                 270         


Ser Val Phe Val Thr Gly Phe Gly Ser Ile Val Asp Asp Gly Pro Ile 
        275                 280                 285             


Gln Asn Thr Leu Arg Gln Ala Arg Val Glu Thr Ile Ser Thr Asp Val 
    290                 295                 300                 


Cys Asn Arg Lys Asp Val Tyr Asp Gly Leu Ile Thr Pro Gly Met Leu 
305                 310                 315                 320 


Cys Ala Gly Phe Met Glu Gly Lys Ile Asp Ala Cys Lys Gly Asp Ser 
                325                 330                 335     


Gly Gly Pro Leu Val Tyr Asp Asn His Asp Ile Trp Tyr Ile Val Gly 
            340                 345                 350         


Ile Val Ser Trp Gly Gln Ser Cys Ala Leu Pro Lys Lys Pro Gly Val 
        355                 360                 365             


Tyr Thr Arg Val Thr Lys Tyr Arg Asp Trp Ile Ala Ser Lys Thr Gly 
    370                 375                 380                 


Met 
385 


<210>  1730
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  1730

Thr Ala Gly Pro Glu Glu Ala Ala Leu Pro Pro Glu Gln Ser Arg Val 
1               5                   10                  15      


Gln Pro Met Thr Ala Ser Asn Trp Thr Leu Val Met Glu Gly Glu Trp 
            20                  25                  30          


Met Leu Lys Phe Tyr Ala Pro Trp Cys Pro Ser Cys Gln Gln Thr Asp 
        35                  40                  45              


Ser Glu Trp Glu Ala Phe Ala Lys Asn Gly Glu Ile Leu Gln Ile Ser 
    50                  55                  60                  


Val Gly Lys Val Asp Val Ile Gln Glu Pro Gly Leu Ser Gly Arg Phe 
65                  70                  75                  80  


Phe Val Thr Thr Leu Pro Ala Phe Phe His Ala Lys Asp Gly Ile Phe 
                85                  90                  95      


Arg Arg Tyr Arg Gly Pro Gly Ile Phe Glu Asp Leu Gln Asn Tyr Ile 
            100                 105                 110         


Leu Glu Lys Lys Trp Gln Ser Val Glu Pro Leu Thr Gly Trp Lys Ser 
        115                 120                 125             


Pro Ala Ser Leu Thr Met Ser Gly Met Ala Gly Leu Phe Ser Ile Ser 
    130                 135                 140                 


Gly Lys Ile Trp His Leu His Asn Tyr Phe Thr Val Thr Leu Gly Ile 
145                 150                 155                 160 


Pro Ala Trp Cys Ser Tyr 
                165     


<210>  1731
<211>  267
<212>  PRT
<213>  Homo Sapiens

<400>  1731

Lys His Phe Trp Pro Glu Val Pro Lys Lys Ala Tyr Asp Met Glu His 
1               5                   10                  15      


Thr Phe Tyr Ser Asn Gly Glu Lys Lys Lys Ile Tyr Met Glu Ile Asp 
            20                  25                  30          


Pro Val Thr Arg Thr Glu Ile Phe Arg Ser Gly Asn Gly Thr Asp Glu 
        35                  40                  45              


Thr Leu Glu Val His Asp Phe Lys Asn Gly Tyr Thr Gly Ile Tyr Phe 
    50                  55                  60                  


Val Gly Leu Gln Lys Cys Phe Ile Lys Thr Gln Ile Lys Val Ile Pro 
65                  70                  75                  80  


Glu Phe Ser Glu Pro Glu Glu Glu Ile Asp Glu Asn Glu Glu Ile Thr 
                85                  90                  95      


Thr Thr Phe Phe Glu Gln Ser Val Ile Trp Val Pro Ala Glu Lys Pro 
            100                 105                 110         


Ile Glu Asn Arg Asp Phe Leu Lys Asn Ser Lys Ile Leu Glu Ile Cys 
        115                 120                 125             


Asp Asn Val Thr Met Tyr Trp Ile Asn Pro Thr Leu Ile Ser Val Ser 
    130                 135                 140                 


Glu Leu Gln Asp Phe Glu Glu Glu Gly Glu Asp Leu His Phe Pro Ala 
145                 150                 155                 160 


Asn Glu Lys Lys Gly Ile Glu Gln Asn Glu Gln Trp Val Val Pro Gln 
                165                 170                 175     


Val Lys Val Glu Lys Thr Arg His Ala Arg Gln Ala Ser Glu Glu Glu 
            180                 185                 190         


Leu Pro Ile Asn Asp Tyr Thr Glu Asn Gly Ile Glu Phe Asp Pro Met 
        195                 200                 205             


Leu Asp Glu Arg Gly Tyr Cys Cys Ile Tyr Cys Arg Arg Gly Asn Arg 
    210                 215                 220                 


Tyr Cys Arg Arg Val Cys Glu Pro Leu Leu Gly Tyr Tyr Pro Tyr Pro 
225                 230                 235                 240 


Tyr Cys Tyr Gln Gly Gly Arg Val Ile Cys Arg Val Ile Met Pro Cys 
                245                 250                 255     


Asn Trp Trp Val Ala Arg Met Leu Gly Arg Val 
            260                 265         


<210>  1732
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  1732

Ala Trp Asp Leu Ala Ser Leu Arg Cys Thr Leu Gly Ala Phe Cys Glu 
1               5                   10                  15      


Cys Asp Phe Arg Pro Asp Leu Pro Gly Leu Glu Cys Asp Leu Ala Gln 
            20                  25                  30          


His Leu Ala Gly Gln His Leu Ala Lys Ala Leu Val Val Lys Ala Leu 
        35                  40                  45              


Lys Ala Phe Val Arg Asp Pro Ala Pro Thr Lys Pro Leu Val Leu Ser 
    50                  55                  60                  


Leu His Gly Trp Thr Gly Thr Gly Lys Ser Tyr Val Ser Ser Leu Leu 
65                  70                  75                  80  


Ala His Tyr Leu Phe Gln Gly Gly Leu Arg Ser Pro Arg Val His His 
                85                  90                  95      


Phe Ser Pro Val Leu His Phe Pro His Pro Ser His Ile Glu Arg Tyr 
            100                 105                 110         


Lys Lys Asp Leu Lys Ser Trp Val Gln Gly Asn Leu Thr Ala Cys Gly 
        115                 120                 125             


Arg Ser Leu Phe Leu Phe Asp Glu Met Asp Lys Met Pro Pro Gly Leu 
    130                 135                 140                 


Met Glu Val Leu Arg Pro Phe Leu Gly Ser Ser Trp Val Val Tyr Gly 
145                 150                 155                 160 


Thr Asn Tyr Arg Lys Ala Ile Phe Ile Phe Ile Arg Trp Leu Leu Lys 
                165                 170                 175     


Leu Gly His His Gly Arg Ala Pro Pro Arg Arg Ser Gly Ala Leu Pro 
            180                 185                 190         


Pro Ala Pro Ala Ala Pro Arg Pro Ala Leu Arg Ala Gln Arg Ala Gly 
        195                 200                 205             


Pro Ala Gly Pro Gly Ala Lys Gly 
    210                 215     


<210>  1733
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  1733

Gly Pro Ala Glu Glu Ala Gly Ala His Cys Pro Glu Ser Leu Trp Pro 
1               5                   10                  15      


Leu Pro Pro Gln Val Ser Pro Arg Val Thr Tyr Thr Arg Val Ser Pro 
            20                  25                  30          


Gly Gln Ala Glu Asp Val Thr Phe Leu Tyr His Pro Cys Ala His Pro 
        35                  40                  45              


Trp Leu Lys Leu Gln Leu Ala Leu Leu Ala Tyr Ala Cys Met Ala Asn 
    50                  55                  60                  


Pro Ser Leu Thr Pro Asp Phe Ser Leu Thr Gln Asp Arg Pro Leu Val 
65                  70                  75                  80  


Leu Thr Ala Trp Gly Leu Ala Leu Glu Met Ala Trp Val Glu Pro Ala 
                85                  90                  95      


Trp Ala Ala His Trp Leu Met Arg Arg Arg Arg Arg Lys Gln Arg Lys 
            100                 105                 110         


Lys Lys Ala Trp Ile Tyr Cys Glu Ser Leu Ser Gly Pro Ala Pro Ser 
        115                 120                 125             


Glu Pro Thr Pro Gly Arg Gly Arg Leu Cys Arg Arg Gly Cys Val Gln 
    130                 135                 140                 


Ala Leu Ala Leu Ala Phe Ala Leu Arg Ser Trp Arg Pro Pro Gly Thr 
145                 150                 155                 160 


Glu Val Thr Ser Gln Gly Pro Arg Gln Pro Ser Ser Ser Gly Ala Lys 
                165                 170                 175     


Arg Arg Arg Leu Arg Ala Ala Leu Gly Pro Gln Pro Thr Arg Ser Ala 
            180                 185                 190         


Leu Arg Phe Pro Ser Ala Ser Pro Gly Ser Leu Lys Ala Lys Gln Ser 
        195                 200                 205             


Met Ala Gly Ile Pro Gly Arg Glu Ser Asn Ala Pro Ser Val Pro Thr 
    210                 215                 220                 


Val Ser Leu Leu Pro Gly Ala Pro Gly Gly Asn Ala Ser Ser Arg Thr 
225                 230                 235                 240 


Glu Ala Gln Val Pro Asn Gly Gln Gly Ser Pro Gly Gly Cys Val Cys 
                245                 250                 255     


Ser Ser Gln Ala Ser Pro Ala Pro Arg Ala Ala Ala Pro Pro Arg Ala 
            260                 265                 270         


Ala Arg Gly Pro Thr Pro Arg Thr Glu Glu 
        275                 280         


<210>  1734
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  1734

Ile Val Gly Gly Gln Glu Ala Pro Arg Ser Lys Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Arg Val His Gly Pro Tyr Trp Met His Phe Cys Gly Gly Ser 
            20                  25                  30          


Leu Ile His Pro Gln Trp Val Leu Thr Ala Ala His Cys Val Gly Pro 
        35                  40                  45              


Asp Val Lys Asp Leu Ala Ala Leu Arg Val Gln Leu Arg Glu Gln His 
    50                  55                  60                  


Leu Tyr Tyr Gln Asp Gln Leu Leu Pro Val Ser Arg Ile Ile Val His 
65                  70                  75                  80  


Pro Gln Phe Tyr Thr Ala Gln Ile Gly Ala Asp Ile Ala Leu Leu Glu 
                85                  90                  95      


Leu Glu Glu Pro Val Asn Val Ser Ser His Val His Thr Val Thr Leu 
            100                 105                 110         


Pro Pro Ala Ser Glu Thr Phe Pro Pro Gly Met Pro Cys Trp Val Thr 
        115                 120                 125             


Gly Trp Gly Asp Val Asp Asn Asp Glu Arg Leu Pro Pro Pro Phe Pro 
    130                 135                 140                 


Leu Lys Gln Val Lys Val Pro Ile Met Glu Asn His Ile Cys Asp Ala 
145                 150                 155                 160 


Lys Tyr His Leu Gly Ala Tyr Thr Gly Asp Asp Val Arg Ile Val Arg 
                165                 170                 175     


Asp Asp Met Leu Cys Ala Gly Asn Thr Arg Arg Asp Ser Cys Gln Gly 
            180                 185                 190         


Asp Ser Gly Gly Pro Leu Val Cys Lys Val Asn Gly Thr Trp Leu Gln 
        195                 200                 205             


Ala Gly Val Val Ser Trp Gly Glu Gly Cys Ala Gln Pro Asn Arg Pro 
    210                 215                 220                 


Gly Ile Tyr Thr Arg Val Thr Tyr Tyr Leu Asp Trp Ile His His Tyr 
225                 230                 235                 240 


Val Pro Lys Lys Pro 
                245 


<210>  1735
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  1735

Ile Val Gly Gly Gln Glu Ala Pro Arg Ser Lys Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Arg Val Arg Gly Pro Tyr Trp Met His Phe Cys Gly Gly Ser 
            20                  25                  30          


Leu Ile His Pro Gln Trp Val Leu Thr Ala Ala His Cys Val Glu Pro 
        35                  40                  45              


Asp Ile Lys Asp Leu Ala Ala Leu Arg Val Gln Leu Arg Glu Gln His 
    50                  55                  60                  


Leu Tyr Tyr Gln Asp Gln Leu Leu Pro Val Ser Arg Ile Ile Val His 
65                  70                  75                  80  


Pro Gln Phe Tyr Ile Ile Gln Thr Gly Ala Asp Ile Ala Leu Leu Glu 
                85                  90                  95      


Leu Glu Glu Pro Val Asn Ile Ser Ser His Ile His Thr Val Thr Leu 
            100                 105                 110         


Pro Pro Ala Ser Glu Thr Phe Pro Pro Gly Met Pro Cys Trp Val Thr 
        115                 120                 125             


Gly Trp Gly Asp Val Asp Asn Asn Val His Leu Pro Pro Pro Tyr Pro 
    130                 135                 140                 


Leu Lys Glu Val Glu Val Pro Val Val Glu Asn His Leu Cys Asn Ala 
145                 150                 155                 160 


Glu Tyr His Thr Gly Leu His Thr Gly His Ser Phe Gln Ile Val Arg 
                165                 170                 175     


Asp Asp Met Leu Cys Ala Gly Ser Glu Asn His Asp Ser Cys Gln Gly 
            180                 185                 190         


Asp Ser Gly Gly Pro Leu Val Cys Lys Val Asn Gly Thr 
        195                 200                 205 


<210>  1736
<211>  475
<212>  PRT
<213>  Homo Sapiens

<400>  1736

Arg Pro Gln Pro Pro Asp Gly Gly Gln Cys Arg Pro Pro Gly Ser Gln 
1               5                   10                  15      


Arg Asp Leu Asn Ser Phe Leu Trp Thr Ile Arg Arg Asp Pro Pro Ala 
            20                  25                  30          


Tyr Leu Phe Gly Thr Ile His Val Pro Tyr Thr Arg Val Trp Asp Phe 
        35                  40                  45              


Ile Pro Asp Asn Ser Lys Ala Ala Phe Gln Ala Ser Thr Arg Val Tyr 
    50                  55                  60                  


Phe Glu Leu Asp Leu Thr Asp Pro Tyr Thr Ile Ser Ala Leu Ala Ser 
65                  70                  75                  80  


Cys Gln Leu Leu Pro His Gly Glu Asn Leu Gln Asp Val Leu Pro His 
                85                  90                  95      


Glu Leu Tyr Trp Arg Leu Lys Arg His Leu Asp Tyr Val Lys Leu Met 
            100                 105                 110         


Met Pro Ser Trp Met Thr Pro Ala Gln Arg Gly Lys Gly Leu Tyr Ala 
        115                 120                 125             


Asp Tyr Leu Phe Asn Ala Ile Ala Gly Asn Trp Glu Arg Lys Arg Pro 
    130                 135                 140                 


Val Trp Val Met Leu Met Val Asn Ser Leu Thr Glu Arg Asp Val Arg 
145                 150                 155                 160 


Phe Arg Gly Val Pro Val Leu Asp Leu Tyr Leu Ala Gln Gln Ala Glu 
                165                 170                 175     


Lys Met Lys Lys Thr Thr Gly Ala Val Glu Gln Val Glu Glu Gln Cys 
            180                 185                 190         


His Pro Leu Asn Asn Gly Leu Asn Phe Ser Gln Val Leu Phe Ala Leu 
        195                 200                 205             


Asn Gln Thr Leu Leu Gln Gln Glu Ser Val Arg Ala Gly Ser Leu Gln 
    210                 215                 220                 


Ala Ser Tyr Thr Thr Glu Asp Leu Ile Lys His Tyr Asn Cys Gly Asp 
225                 230                 235                 240 


Leu Ser Ala Val Ile Phe Asn His Asp Thr Ser Gln Leu Pro Asn Phe 
                245                 250                 255     


Ile Asn Thr Thr Leu Pro Pro His Glu Gln Val Thr Ala Gln Glu Ile 
            260                 265                 270         


Asp Ser Tyr Phe Arg Gln Glu Leu Ile Tyr Lys Arg Asn Glu Arg Met 
        275                 280                 285             


Gly Lys Arg Val Met Ala Leu Leu Arg Glu Asn Glu Asp Lys Ile Cys 
    290                 295                 300                 


Phe Phe Ala Phe Gly Ala Gly His Phe Leu Gly Asn Asn Thr Val Ile 
305                 310                 315                 320 


Asp Ile Leu Arg Gln Ala Gly Leu Glu Val Asp His Thr Pro Ala Gly 
                325                 330                 335     


Gln Ala Ile His Ser Pro Ala Pro Gln Ser Pro Ala Pro Ser Pro Glu 
            340                 345                 350         


Gly Thr Ser Thr Ser Pro Ala Pro Val Thr Pro Ala Ala Ala Val Pro 
        355                 360                 365             


Glu Ala Pro Ser Val Thr Pro Thr Ala Pro Pro Glu Asp Glu Asp Pro 
    370                 375                 380                 


Ala Leu Ser Pro His Leu Leu Leu Pro Asp Ser Leu Ser Gln Leu Glu 
385                 390                 395                 400 


Glu Phe Gly Arg Gln Arg Lys Trp His Lys Arg Gln Ser Thr His Gln 
                405                 410                 415     


Arg Pro Arg Gln Phe Asn Asp Leu Trp Val Arg Ile Glu Asp Ser Thr 
            420                 425                 430         


Thr Ala Ser Pro Pro Pro Leu Pro Leu Gln Pro Thr His Ser Ser Gly 
        435                 440                 445             


Thr Ala Lys Pro Pro Phe Gln Leu Ser Asp Gln Leu Gln Gln Gln Asp 
    450                 455                 460                 


Pro Pro Gly Pro Ala Ser Ser Ser Ala Pro Thr 
465                 470                 475 


<210>  1737
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  1737

Met Pro Leu Arg Asp Glu Thr Leu Arg Glu Val Trp Ala Ser Asp Ser 
1               5                   10                  15      


Gly His Glu Glu Glu Ser Leu Ser Pro Glu Ala Pro Arg Arg Pro Lys 
            20                  25                  30          


Gln Arg Pro Ala Pro Ala Gln Arg Leu Arg Lys Lys Arg Thr Glu Ala 
        35                  40                  45              


Pro Glu Ser Pro Cys Pro Thr Gly Ser Lys Pro Arg Lys Pro Gly Ala 
    50                  55                  60                  


Gly Arg Thr Gly Arg Pro Arg Glu Glu Pro Ser Pro Asp Pro Ala Gln 
65                  70                  75                  80  


Ala Arg Ala Pro Gln Thr Val Tyr Ala Arg Phe Leu Arg Asp Pro Glu 
                85                  90                  95      


Ala Lys Lys Arg Asp Pro Arg Glu Thr Phe Leu Val Ala Arg Ala Pro 
            100                 105                 110         


Asp Ala Glu Asp Glu Glu Glu Glu Glu Glu Glu Asp Glu Glu Asp Glu 
        115                 120                 125             


Glu Glu Glu Ala Glu Glu Lys Lys Glu Lys Ile Leu Leu Pro Pro Lys 
    130                 135                 140                 


Lys Pro Leu Arg Glu Lys Ser Ser Ala Asp Leu Lys Glu Arg Arg Ala 
145                 150                 155                 160 


Lys Ala Gln Gly Pro Arg Gly Asp Leu Gly Ser Pro Asp Pro Pro Pro 
                165                 170                 175     


Lys Pro Leu Arg Val Arg Asn Lys Glu Ala Pro Ala Gly Glu Gly Thr 
            180                 185                 190         


Lys Met Arg Lys Thr Lys Lys Lys Gly Ser Gly Glu Ala Asp Lys Asp 
        195                 200                 205             


Pro Ser Gly Ser Pro Ala Ser Ala Arg Lys Ser Pro Ala Ala Met Phe 
    210                 215                 220                 


Leu Val Gly Glu Gly Ser Pro Asp Lys Lys Ala Leu Lys Lys Lys Gly 
225                 230                 235                 240 


Thr Pro Lys Gly Ala Arg Lys Glu Glu Glu Glu Glu Glu Glu Ala Ala 
                245                 250                 255     


Thr Val Ile Lys Lys Ser Asn Gln Lys Gly Lys Ala Lys Gly Lys Gly 
            260                 265                 270         


Lys Lys Lys Ala Lys Glu Glu Arg Ala Pro Ser Pro Pro Val Glu Val 
        275                 280                 285             


Asp Glu Pro Arg Glu Phe Val Leu Arg Pro Ala Pro Gln Gly Arg Thr 
    290                 295                 300                 


Val Arg Cys Arg Leu Thr Arg Asp Lys Lys Gly Met Asp Arg Gly Met 
305                 310                 315                 320 


Tyr Pro Ser Tyr Phe Leu His Leu Asp Thr Glu Lys Lys Val Phe Leu 
                325                 330                 335     


Leu Ala Gly Arg Lys Arg Lys Arg Ser Lys Thr Ala Asn Tyr Leu Ile 
            340                 345                 350         


Ser Ile Asp Pro Thr Asn Leu Ser Arg Gly Gly Glu Asn Phe Ile Gly 
        355                 360                 365             


Lys Leu Arg Ser Asn Leu Leu Gly Asn Arg Phe Thr Val Phe Asp Asn 
    370                 375                 380                 


Gly Gln Asn Pro Gln Arg Gly Tyr Ser Thr Asn Val Ala Ser Leu Arg 
385                 390                 395                 400 


Gln Glu Leu Ala Ala Val Ile Tyr Glu Thr Asn Val Leu Gly Phe Arg 
                405                 410                 415     


Gly Pro Arg Arg Met Thr Val Ile Ile Pro Gly Met Ser Ala Glu Asn 
            420                 425                 430         


Glu Arg Val Pro Ile Arg Pro Arg Asn Ala Ser Asp Gly Leu Leu Val 
        435                 440                 445             


Arg Trp Gln Asn Lys Thr Leu Glu Ser Leu Ile Glu Leu His Asn Lys 
    450                 455                 460                 


Pro Pro Val Trp Asn Asp Asp Ser Gly Ser Tyr Thr Leu Asn Phe Gln 
465                 470                 475                 480 


Gly Arg Val Thr Gln Ala Ser Val Lys Asn Phe Gln Ile Val His Ala 
                485                 490                 495     


Asp Asp Pro Asp Tyr Ile Val Leu Gln Phe Gly Arg Val Ala Glu Asp 
            500                 505                 510         


Ala Phe Thr Leu Asp Tyr Arg Tyr Pro Leu Cys Ala Leu Gln Ala Phe 
        515                 520                 525             


Ala Ile Ala Leu Ser Ser Phe Asp Gly Lys Leu Ala Cys Glu 
    530                 535                 540         


<210>  1738
<211>  442
<212>  PRT
<213>  Homo Sapiens

<400>  1738

Met Glu Ala Ser Arg Cys Arg Leu Ser Pro Ser Gly Asp Ser Val Phe 
1               5                   10                  15      


His Glu Glu Met Met Lys Met Arg Gln Ala Lys Leu Asp Tyr Gln Arg 
            20                  25                  30          


Leu Leu Leu Glu Lys Arg Gln Arg Lys Lys Arg Leu Glu Pro Phe Met 
        35                  40                  45              


Val Gln Pro Asn Pro Glu Ala Arg Leu Arg Arg Ala Lys Pro Arg Ala 
    50                  55                  60                  


Ser Asp Glu Gln Thr Pro Leu Val Asn Cys His Thr Pro His Ser Asn 
65                  70                  75                  80  


Val Ile Leu His Gly Ile Asp Gly Pro Ala Ala Val Leu Lys Pro Asp 
                85                  90                  95      


Glu Val His Ala Pro Ser Val Ser Ser Ser Val Val Glu Glu Asp Ala 
            100                 105                 110         


Glu Asn Thr Val Asp Thr Ala Ser Lys Pro Gly Leu Gln Glu Arg Leu 
        115                 120                 125             


Gln Lys His Asp Ile Ser Glu Ser Val Asn Phe Asp Glu Glu Thr Asp 
    130                 135                 140                 


Gly Ile Ser Gln Ser Ala Cys Leu Glu Arg Pro Asn Ser Ala Ser Ser 
145                 150                 155                 160 


Gln Asn Ser Thr Asp Thr Gly Thr Ser Gly Ser Ala Thr Ala Ala Gln 
                165                 170                 175     


Pro Ala Asp Asn Leu Leu Gly Asp Ile Asp Asp Leu Glu Asp Phe Val 
            180                 185                 190         


Tyr Ser Pro Ala Pro Gln Gly Val Thr Val Arg Cys Arg Ile Ile Arg 
        195                 200                 205             


Asp Lys Arg Gly Met Asp Arg Gly Leu Phe Pro Thr Tyr Tyr Met Tyr 
    210                 215                 220                 


Leu Glu Lys Glu Glu Asn Gln Lys Ile Phe Leu Leu Ala Ala Arg Lys 
225                 230                 235                 240 


Arg Lys Lys Ser Lys Thr Ala Asn Tyr Leu Ile Ser Ile Asp Pro Val 
                245                 250                 255     


Asp Leu Ser Arg Glu Gly Glu Ser Tyr Val Gly Lys Leu Arg Ser Asn 
            260                 265                 270         


Leu Met Gly Thr Lys Phe Thr Val Tyr Asp Arg Gly Ile Cys Pro Met 
        275                 280                 285             


Lys Gly Arg Gly Leu Val Gly Ala Ala His Thr Arg Gln Glu Leu Ala 
    290                 295                 300                 


Ala Ile Ser Tyr Glu Thr Asn Val Leu Gly Phe Lys Gly Pro Arg Lys 
305                 310                 315                 320 


Met Ser Val Ile Ile Pro Gly Met Thr Leu Asn His Lys Gln Ile Pro 
                325                 330                 335     


Tyr Gln Pro Gln Asn Asn His Asp Ser Leu Leu Ser Arg Trp Gln Asn 
            340                 345                 350         


Arg Thr Met Glu Asn Leu Val Glu Leu His Asn Lys Ala Pro Val Trp 
        355                 360                 365             


Asn Ser Asp Thr Gln Ser Tyr Val Leu Asn Phe Arg Gly Arg Val Thr 
    370                 375                 380                 


Gln Ala Ser Val Lys Asn Phe Gln Ile Val His Lys Asn Asp Pro Asp 
385                 390                 395                 400 


Tyr Ile Val Met Gln Phe Gly Arg Val Ala Asp Asp Val Phe Thr Leu 
                405                 410                 415     


Asp Tyr Asn Tyr Pro Leu Cys Ala Val Gln Ala Phe Gly Ile Gly Leu 
            420                 425                 430         


Ser Ser Phe Asp Ser Lys Leu Ala Cys Glu 
        435                 440         


<210>  1739
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  1739

Val Lys Gln Ile Glu Ser Lys Thr Ala Phe Gln Glu Ala Leu Asp Ala 
1               5                   10                  15      


Ala Gly Asp Lys Leu Val Val Val Asp Phe Ser Ala Thr Trp Cys Gly 
            20                  25                  30          


Pro Cys Lys Met Ile Lys Pro Phe Phe His Ser Leu Ser Glu Lys Tyr 
        35                  40                  45              


Ser Asn Val Ile Phe Leu Glu Val Asp Val Asp Asp Cys Gln Asp Val 
    50                  55                  60                  


Ala Ser Glu Cys Glu Val Lys Cys Met Pro Thr Phe Gln Phe Phe Lys 
65                  70                  75                  80  


Lys Gly Gln Lys Val Gly Glu Phe Ser Gly Ala Asn Lys Glu Lys Leu 
                85                  90                  95      


Glu Ala Thr Ile Asn Glu Leu Val 
            100                 


<210>  1740
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  1740

Ser Pro Lys Ser Arg Asp Glu Val Asn Val Glu Asn Arg Gln Lys Leu 
1               5                   10                  15      


Arg Val Asp Glu Leu Arg Arg Glu Tyr Tyr Glu Glu Gln Arg Asn Glu 
            20                  25                  30          


Phe Glu Asn Phe Val Glu Glu Gln Asn Asp Glu Gln Glu Glu Arg Ser 
        35                  40                  45              


Arg Glu Ala Val Glu Gln Trp Arg Gln Trp His Tyr Asp Gly Leu His 
    50                  55                  60                  


Pro Ser Tyr Leu Tyr Asn Arg His His Thr 
65                  70                  


<210>  1741
<211>  470
<212>  PRT
<213>  Homo Sapiens

<400>  1741

Gly Asn Val Leu Ile Trp Pro Met Glu Gly Ser His Trp Leu Asn Val 
1               5                   10                  15      


Lys Ile Ile Ile Asp Glu Leu Ile Lys Lys Glu His Asn Val Thr Val 
            20                  25                  30          


Leu Val Ala Ser Gly Ala Leu Phe Ile Thr Pro Thr Ser Asn Pro Ser 
        35                  40                  45              


Leu Thr Phe Glu Ile Tyr Arg Val Pro Phe Gly Lys Glu Arg Ile Glu 
    50                  55                  60                  


Gly Val Ile Lys Asp Phe Val Leu Thr Trp Leu Glu Asn Arg Pro Ser 
65                  70                  75                  80  


Pro Ser Thr Ile Trp Arg Phe Tyr Gln Glu Met Ala Lys Val Ile Lys 
                85                  90                  95      


Asp Phe His Met Val Ser Gln Glu Ile Cys Asp Gly Val Leu Lys Asn 
            100                 105                 110         


Gln Gln Leu Met Ala Lys Leu Lys Lys Ser Lys Phe Glu Val Leu Val 
        115                 120                 125             


Ser Asp Pro Val Phe Pro Cys Gly Asp Ile Val Ala Leu Lys Leu Gly 
    130                 135                 140                 


Ile Pro Phe Met Tyr Ser Leu Arg Phe Ser Pro Ala Ser Thr Val Glu 
145                 150                 155                 160 


Lys His Cys Gly Lys Val Pro Tyr Pro Pro Ser Tyr Val Pro Ala Val 
                165                 170                 175     


Leu Ser Glu Leu Thr Asp Gln Met Ser Phe Thr Asp Arg Ile Arg Asn 
            180                 185                 190         


Phe Ile Ser Tyr His Leu Gln Asp Tyr Met Phe Glu Thr Leu Trp Lys 
        195                 200                 205             


Ser Trp Asp Ser Tyr Tyr Ser Lys Ala Leu Gly Arg Pro Thr Thr Leu 
    210                 215                 220                 


Cys Glu Thr Met Gly Lys Ala Glu Ile Trp Leu Ile Arg Thr Tyr Trp 
225                 230                 235                 240 


Asp Phe Glu Phe Pro Arg Pro Tyr Leu Pro Asn Phe Glu Phe Val Gly 
                245                 250                 255     


Gly Leu His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu 
            260                 265                 270         


Phe Ile Gln Ser Ser Gly Lys Asn Gly Val Val Val Phe Ser Leu Gly 
        275                 280                 285             


Ser Met Val Lys Asn Leu Thr Glu Glu Lys Ala Asn Leu Ile Ala Ser 
    290                 295                 300                 


Ala Leu Ala Gln Ile Pro Gln Lys Val Leu Trp Arg Tyr Lys Gly Lys 
305                 310                 315                 320 


Lys Pro Ala Thr Leu Gly Asn Asn Thr Gln Leu Phe Asp Trp Ile Pro 
                325                 330                 335     


Gln Asn Asp Leu Leu Gly His Pro Lys Thr Lys Ala Phe Ile Thr His 
            340                 345                 350         


Gly Gly Thr Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Val Pro Met 
        355                 360                 365             


Val Gly Val Pro Met Phe Ala Asp Gln Pro Asp Asn Ile Ala His Met 
    370                 375                 380                 


Lys Ala Lys Gly Ala Ala Val Glu Val Asn Leu Asn Thr Met Thr Ser 
385                 390                 395                 400 


Val Asp Leu Leu Ser Ala Leu Arg Thr Val Ile Asn Glu Pro Ser Tyr 
                405                 410                 415     


Lys Glu Asn Ala Met Arg Leu Ser Arg Ile His His Asp Gln Pro Val 
            420                 425                 430         


Lys Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His 
        435                 440                 445             


Lys Gly Ala Lys His Leu Arg Val Ala Ala His Asp Leu Thr Trp Phe 
    450                 455                 460                 


Gln Tyr His Ser Leu Asp 
465                 470 


<210>  1742
<211>  468
<212>  PRT
<213>  Homo Sapiens

<400>  1742

Lys Val Leu Val Trp Ala Ala Glu Tyr Ser Leu Trp Met Asn Met Lys 
1               5                   10                  15      


Thr Ile Leu Lys Glu Leu Val Gln Arg Gly His Glu Val Thr Val Leu 
            20                  25                  30          


Ala Ser Ser Ala Ser Ile Leu Phe Asp Pro Asn Asp Ser Ser Thr Leu 
        35                  40                  45              


Lys Leu Glu Val Tyr Pro Thr Ser Leu Thr Lys Thr Glu Phe Glu Asn 
    50                  55                  60                  


Ile Ile Met Gln Leu Val Lys Arg Leu Ser Glu Ile Gln Lys Asp Thr 
65                  70                  75                  80  


Phe Trp Leu Pro Phe Ser Gln Glu Gln Glu Ile Leu Trp Ala Ile Asn 
                85                  90                  95      


Asp Ile Ile Arg Asn Phe Cys Lys Asp Val Val Ser Asn Lys Lys Leu 
            100                 105                 110         


Met Lys Lys Leu Gln Glu Ser Arg Phe Asp Ile Val Phe Ala Asp Ala 
        115                 120                 125             


Tyr Leu Pro Cys Gly Glu Leu Leu Ala Glu Leu Phe Asn Ile Pro Phe 
    130                 135                 140                 


Val Tyr Ser His Ser Phe Ser Pro Gly Tyr Ser Phe Glu Arg His Ser 
145                 150                 155                 160 


Gly Gly Phe Ile Phe Pro Pro Ser Tyr Val Pro Val Val Met Ser Lys 
                165                 170                 175     


Leu Ser Asp Gln Met Thr Phe Met Glu Arg Val Lys Asn Met Leu Tyr 
            180                 185                 190         


Val Leu Tyr Phe Asp Phe Trp Phe Gln Ile Phe Asn Met Lys Lys Trp 
        195                 200                 205             


Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu Ser Glu 
    210                 215                 220                 


Thr Met Arg Lys Ala Asp Ile Trp Leu Met Arg Asn Ser Trp Asn Phe 
225                 230                 235                 240 


Lys Phe Pro His Pro Phe Leu Pro Asn Val Asp Phe Val Gly Gly Leu 
                245                 250                 255     


His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu Phe Val 
            260                 265                 270         


Gln Ser Ser Gly Glu Asn Gly Val Val Val Phe Ser Leu Gly Ser Met 
        275                 280                 285             


Val Ser Asn Met Thr Glu Glu Arg Ala Asn Val Ile Ala Thr Ala Leu 
    290                 295                 300                 


Ala Lys Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Asn Lys Pro 
305                 310                 315                 320 


Asp Ala Leu Gly Leu Asn Thr Arg Leu Tyr Lys Trp Ile Pro Gln Asn 
                325                 330                 335     


Asp Leu Leu Gly His Pro Lys Thr Arg Ala Phe Ile Thr His Gly Gly 
            340                 345                 350         


Ala Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met Val Gly 
        355                 360                 365             


Ile Pro Leu Phe Phe Asp Gln Pro Asp Asn Ile Ala His Met Lys Ala 
    370                 375                 380                 


Lys Gly Ala Ala Val Arg Val Asp Phe Asn Thr Met Ser Ser Thr Asp 
385                 390                 395                 400 


Leu Leu Asn Ala Leu Lys Thr Val Ile Asn Asp Pro Ser Tyr Lys Glu 
                405                 410                 415     


Asn Ile Met Lys Leu Ser Arg Ile Gln His Asp Gln Pro Val Lys Pro 
            420                 425                 430         


Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His Lys Gly 
        435                 440                 445             


Ala Lys His Leu Arg Val Ala Ala His Asn Leu Thr Trp Phe Gln Tyr 
    450                 455                 460                 


His Ser Leu Asp 
465             


<210>  1743
<211>  470
<212>  PRT
<213>  Homo Sapiens

<400>  1743

Lys Val Leu Val Trp Thr Gly Glu Tyr Ser His Trp Met Asn Met Lys 
1               5                   10                  15      


Thr Ile Leu Lys Glu Leu Val Gln Arg Gly His Glu Val Thr Val Leu 
            20                  25                  30          


Ala Ser Ser Ala Ser Ile Leu Phe Asp Pro Asn Asp Ala Phe Thr Leu 
        35                  40                  45              


Lys Leu Glu Val Tyr Pro Thr Ser Leu Thr Lys Thr Glu Phe Glu Asn 
    50                  55                  60                  


Ile Ile Met Gln Gln Val Lys Arg Trp Ser Asp Ile Gln Lys Asp Ser 
65                  70                  75                  80  


Phe Trp Leu Tyr Phe Ser Gln Glu Gln Glu Ile Leu Trp Glu Phe His 
                85                  90                  95      


Asp Ile Phe Arg Asn Phe Cys Lys Asp Val Val Ser Asn Lys Lys Val 
            100                 105                 110         


Met Lys Lys Leu Gln Glu Ser Arg Phe Asp Ile Ile Phe Ala Asp Ala 
        115                 120                 125             


Phe Phe Pro Cys Gly Glu Leu Leu Ala Ala Leu Leu Asn Ile Pro Phe 
    130                 135                 140                 


Val Tyr Ser Leu Cys Phe Thr Pro Gly Tyr Thr Ile Glu Arg His Ser 
145                 150                 155                 160 


Gly Gly Leu Ile Phe Pro Pro Ser Tyr Ile Pro Val Val Met Ser Lys 
                165                 170                 175     


Leu Ser Asp Gln Met Thr Phe Met Glu Arg Val Lys Asn Met Ile Tyr 
            180                 185                 190         


Val Leu Tyr Phe Asp Phe Trp Phe Gln Met Cys Asp Met Lys Lys Trp 
        195                 200                 205             


Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu Phe Glu 
    210                 215                 220                 


Thr Met Gly Lys Ala Asp Ile Trp Leu Met Arg Asn Ser Trp Ser Phe 
225                 230                 235                 240 


Gln Phe Pro His Pro Phe Leu Pro Asn Ile Asp Phe Val Gly Gly Leu 
                245                 250                 255     


His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu Phe Val 
            260                 265                 270         


Gln Ser Ser Gly Glu Asn Gly Val Val Val Phe Ser Leu Gly Ser Val 
        275                 280                 285             


Ile Ser Asn Met Thr Ala Glu Arg Ala Asn Val Ile Ala Thr Ala Leu 
    290                 295                 300                 


Ala Lys Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Asn Lys Pro 
305                 310                 315                 320 


Asp Ala Leu Gly Leu Asn Thr Arg Leu Tyr Lys Trp Ile Pro Gln Asn 
                325                 330                 335     


Asp Leu Leu Gly Leu Pro Lys Thr Arg Ala Phe Ile Thr His Gly Gly 
            340                 345                 350         


Ala Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met Val Gly 
        355                 360                 365             


Ile Pro Leu Phe Trp Asp Gln Pro Asp Asn Ile Ala His Met Lys Ala 
    370                 375                 380                 


Lys Gly Ala Ala Val Arg Leu Asp Phe His Thr Met Ser Ser Thr Asp 
385                 390                 395                 400 


Leu Leu Asn Ala Leu Lys Thr Val Ile Asn Asp Pro Ser Tyr Lys Glu 
                405                 410                 415     


Asn Val Met Lys Leu Ser Ile Ile Gln His Asp Gln Pro Val Lys Pro 
            420                 425                 430         


Leu His Arg Ala Val Phe Trp Ile Glu Phe Val Met Cys His Lys Gly 
        435                 440                 445             


Ala Lys His Leu Arg Val Ala Ala Arg Asp Leu Thr Trp Phe Gln Tyr 
    450                 455                 460                 


His Ser Leu Asp Val Ile 
465                 470 


<210>  1744
<211>  451
<212>  PRT
<213>  Homo Sapiens

<400>  1744

Ala Lys Ile Ile Ile Val Pro Pro Ile Met Phe Glu Ser His Met Tyr 
1               5                   10                  15      


Ile Phe Lys Thr Leu Ala Ser Ala Leu His Glu Arg Gly His His Thr 
            20                  25                  30          


Val Phe Leu Leu Ser Glu Gly Arg Asp Ile Ala Pro Ser Asn His Tyr 
        35                  40                  45              


Ser Leu Gln Arg Tyr Pro Gly Ile Phe Asn Ser Thr Thr Ser Asp Ala 
    50                  55                  60                  


Phe Leu Gln Ser Lys Met Arg Asn Ile Phe Ser Gly Arg Leu Thr Ala 
65                  70                  75                  80  


Ile Glu Leu Phe Asp Ile Leu Asp His Tyr Thr Lys Asn Cys Asp Leu 
                85                  90                  95      


Met Val Gly Asn His Ala Leu Ile Gln Gly Leu Lys Lys Glu Lys Phe 
            100                 105                 110         


Asp Leu Leu Leu Val Asp Pro Asn Asp Met Cys Gly Phe Val Ile Ala 
        115                 120                 125             


His Leu Leu Gly Val Lys Tyr Ala Val Phe Ser Thr Gly Leu Trp Tyr 
    130                 135                 140                 


Pro Ala Glu Val Gly Ala Pro Ala Pro Leu Ala Tyr Val Pro Glu Phe 
145                 150                 155                 160 


Asn Ser Leu Leu Thr Asp Arg Met Asn Leu Leu Gln Arg Met Lys Asn 
                165                 170                 175     


Thr Gly Val Tyr Leu Ile Ser Arg Leu Gly Val Ser Phe Leu Val Leu 
            180                 185                 190         


Pro Lys Tyr Glu Arg Ile Met Gln Lys Tyr Asn Leu Leu Pro Glu Lys 
        195                 200                 205             


Ser Met Tyr Asp Leu Val His Gly Ser Ser Leu Trp Met Leu Cys Thr 
    210                 215                 220                 


Asp Val Ala Leu Glu Phe Pro Arg Pro Thr Leu Pro Asn Val Val Tyr 
225                 230                 235                 240 


Val Gly Gly Ile Leu Thr Lys Pro Ala Ser Pro Leu Pro Glu Asp Leu 
                245                 250                 255     


Gln Arg Trp Val Asn Gly Ala Asn Glu His Gly Phe Val Leu Val Ser 
            260                 265                 270         


Phe Gly Ala Gly Val Lys Tyr Leu Ser Glu Asp Ile Ala Asn Lys Leu 
        275                 280                 285             


Ala Gly Ala Leu Gly Arg Leu Pro Gln Lys Val Ile Trp Arg Phe Ser 
    290                 295                 300                 


Gly Pro Lys Pro Lys Asn Leu Gly Asn Asn Thr Lys Leu Ile Glu Trp 
305                 310                 315                 320 


Leu Pro Gln Asn Asp Leu Leu Gly His Ser Lys Ile Lys Ala Phe Leu 
                325                 330                 335     


Ser His Gly Gly Leu Asn Ser Ile Phe Glu Thr Ile Tyr His Gly Val 
            340                 345                 350         


Pro Val Val Gly Ile Pro Leu Phe Gly Asp His Tyr Asp Thr Met Thr 
        355                 360                 365             


Arg Val Gln Ala Lys Gly Met Gly Ile Leu Leu Glu Trp Lys Thr Val 
    370                 375                 380                 


Thr Glu Lys Glu Leu Tyr Glu Ala Leu Val Lys Val Ile Asn Asn Pro 
385                 390                 395                 400 


Ser Tyr Arg Gln Arg Ala Gln Lys Leu Ser Glu Ile His Lys Asp Gln 
                405                 410                 415     


Pro Gly His Pro Val Asn Arg Thr Ile Tyr Trp Ile Asp Tyr Ile Ile 
            420                 425                 430         


Arg His Asn Gly Ala His His Leu Arg Ala Ala Val His Gln Ile Ser 
        435                 440                 445             


Phe Cys Gln 
    450     


<210>  1745
<211>  188
<212>  PRT
<213>  Homo Sapiens

<400>  1745

Asp Ala His Ser Leu Trp Tyr Asn Phe Thr Ile Ile His Leu Pro Arg 
1               5                   10                  15      


His Gly Gln Gln Trp Cys Glu Val Gln Ser Gln Val Asp Gln Lys Asn 
            20                  25                  30          


Phe Leu Ser Tyr Asp Cys Gly Ser Asp Lys Val Leu Ser Met Gly His 
        35                  40                  45              


Leu Glu Glu Gln Leu Tyr Ala Thr Asp Ala Trp Gly Lys Gln Leu Glu 
    50                  55                  60                  


Met Leu Arg Glu Val Gly Gln Arg Leu Arg Leu Glu Leu Ala Asp Thr 
65                  70                  75                  80  


Glu Leu Glu Asp Phe Thr Pro Ser Gly Pro Leu Thr Leu Gln Val Arg 
                85                  90                  95      


Met Ser Cys Glu Cys Glu Ala Asp Gly Tyr Ile Arg Gly Ser Trp Gln 
            100                 105                 110         


Phe Ser Phe Asp Gly Arg Lys Phe Leu Leu Phe Asp Ser Asn Asn Arg 
        115                 120                 125             


Lys Trp Thr Val Val His Ala Gly Ala Arg Arg Met Lys Glu Lys Trp 
    130                 135                 140                 


Glu Lys Asp Ser Gly Leu Thr Thr Phe Phe Lys Met Val Ser Met Arg 
145                 150                 155                 160 


Asp Cys Lys Ser Trp Leu Arg Asp Phe Leu Met His Arg Lys Lys Arg 
                165                 170                 175     


Leu Glu Pro Thr Ala Pro Pro Thr Met Ala Pro Gly 
            180                 185             


<210>  1746
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  1746

His Glu Ala His Lys Thr Ser Leu Ser Ser Trp Lys His Asp Gln Asp 
1               5                   10                  15      


Trp Ala Asn Val Ser Asn Met Thr Phe Ser Asn Gly Lys Leu Arg Val 
            20                  25                  30          


Lys Gly Ile Tyr Tyr Arg Asn Ala Asp Ile Cys Ser Arg His Arg Val 
        35                  40                  45              


Thr Ser Ala Gly Leu Thr Leu Gln Asp Leu Gln Leu Trp Cys Asn Leu 
    50                  55                  60                  


Arg Ser Val Ala Arg Gly Gln Ile Pro Ser Thr Leu 
65                  70                  75      


<210>  1747
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  1747

Met Leu Glu Glu Ala Ala Ser Pro Asn Glu Ala Val His Ala Ser Thr 
1               5                   10                  15      


Ser Gly Ser Gly Ala Leu Thr Asp Gln Thr Phe Thr Asp Leu Ser Ala 
            20                  25                  30          


Ala Glu Ala Ser Ser Glu Glu Val Pro Asp Phe Met Glu Val Pro His 
        35                  40                  45              


Ser Val His His Lys Ile Asn Cys Phe Phe Tyr Leu Glu Lys Gln Leu 
    50                  55                  60                  


Cys Gln Leu Pro Ser Pro Leu Cys Leu Ser Ser Leu Leu Thr Leu Lys 
65                  70                  75                  80  


Leu Lys Thr Thr Val Pro Ala Pro Gly Arg Trp Trp Ser Phe Gln Pro 
                85                  90                  95      


His Lys Ala Phe Pro Leu Leu Val Gly Thr Pro Gly Ser Trp Gln Ser 
            100                 105                 110         


Thr Ile Asp Pro Ala Trp Ala Ala Pro Ser Gln Pro Ser Pro Gly 
        115                 120                 125         


<210>  1748
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  1748

Gly Arg Asp Pro Ser Ala Ser Arg Ala Arg Phe Pro Gln Arg Leu Gly 
1               5                   10                  15      


Arg Ala Pro Cys Phe Glu Val Gly Leu Arg Lys Pro Pro Pro Pro Pro 
            20                  25                  30          


Leu Leu Ser Pro Pro Ser Phe Ser Ser Gly Ser Ser Arg Pro Leu Gln 
        35                  40                  45              


Arg Pro Arg Gly Pro Lys Asp Gly Ala Gly Arg Lys Val Cys Ala Lys 
    50                  55                  60                  


Leu Val Lys Arg Leu Pro Gly Glu Ser Gly Ser Cys Glu Asp Gly Gln 
65                  70                  75                  80  


Ser Ala Pro Ala Gln Pro Pro Arg Arg Arg Thr Gly Thr Arg Ala Cys 
                85                  90                  95      


Pro Pro Arg Ala Pro Leu Trp Arg 
            100                 


<210>  1749
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  1749

Phe Asn Val Leu Ile Pro Lys Arg Asp Glu Asp Gly Asp Gly Glu Gly 
1               5                   10                  15      


Pro Gly Asp Val Thr Ala Gly Val Ser Arg Ala Ala Gly Ser Pro Ser 
            20                  25                  30          


Gly Trp Glu Ala Pro Trp Val Gln Gln Pro Arg Cys Cys Arg Arg Ala 
        35                  40                  45              


Thr Pro Val Cys Cys Ala Gly Gln Gly Pro Pro Arg Ser Leu Gln Gln 
    50                  55                  60                  


Gly Gly Ser Glu Val Leu Leu Gly Gln Leu Cys Ser Pro Glu Pro Asp 
65                  70                  75                  80  


Trp Leu Pro Ser Ser Gly Pro Lys Val Ala Lys Gln Val Phe Gln Val 
                85                  90                  95      


Ala Ala Glu Leu Leu Gln His Pro Glu His Phe Val Pro Ser Ser Val 
            100                 105                 110         


Pro Glu Gly Cys Val His Lys Pro Gly Ser Thr Cys Asp Gly Ser Leu 
        115                 120                 125             


Lys Gly Arg Ala Tyr Pro Ser Cys Val Pro Lys Arg Asp Pro Glu His 
    130                 135                 140                 


Ser Arg Glu Glu Ser His Pro Leu Ser Gly 
145                 150                 


<210>  1750
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  1750

Gln Pro Leu Pro Gly Asn Thr Thr Glu Ala Thr Pro Arg Ser Leu Arg 
1               5                   10                  15      


Ala Ser Gly Ser Leu Cys Gly Pro His Ala Lys Ala Pro Tyr Leu Cys 
            20                  25                  30          


Glu Ala Thr His Glu Pro Ala Ala Ala Arg Ile Arg Ala Gln Val Pro 
        35                  40                  45              


Asp Thr Arg Trp Ser Arg Val Gly Gly Gln Arg Phe Tyr Ser Arg Val 
    50                  55                  60                  


Leu Ser Pro Leu His Arg Gly Pro Ser Gly His Thr Glu Ala Ser Ala 
65                  70                  75                  80  


Gln Arg Ser His Met Gly Lys Leu Lys Glu Pro Gln Pro Gln Asp His 
                85                  90                  95      


Lys Pro Gly Leu Gly Ala Ser 
            100             


<210>  1751
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  1751

Leu Pro Leu Pro Ser Tyr Leu His His Thr Ile Asn Leu Thr His Ser 
1               5                   10                  15      


Leu Leu Ala Ala Ser Asn Pro Ser Leu Val Asn Asn Cys Trp Leu Cys 
            20                  25                  30          


Ile Ser Leu Ser Ser Ser Ala Tyr Thr Ala Val Pro Ala Val Gln Thr 
        35                  40                  45              


Asp Trp Ala Thr Ser Pro Ile Ser Leu His Leu Arg Thr Ser Phe Asn 
    50                  55                  60                  


Ser Pro His Leu Tyr Pro Pro Glu Glu Leu Ile Tyr Phe Leu Asp Arg 
65                  70                  75                  80  


Ser Ser Lys Thr Ser Pro Asp Ile Ser His Gln Gln Ala Ala Ala Leu 
                85                  90                  95      


Leu Arg Thr Tyr Leu Lys Asn Leu Ser Pro Tyr Ile Asn Ser Thr Pro 
            100                 105                 110         


Pro Ile Phe Gly Pro Leu Thr Thr Gln Thr Thr Ile Pro Val Ala Ala 
        115                 120                 125             


Pro Leu Cys Ile Ser Trp Gln Arg Pro Thr Gly Ile Pro Leu Gly Asn 
    130                 135                 140                 


Leu Ser Pro Ser Arg Cys Ser Phe Thr Leu His Leu Arg Ser Pro Thr 
145                 150                 155                 160 


Thr Asn Ile Asn Glu Thr Ile Gly Ala Phe Gln Leu His Ile Thr Asp 
                165                 170                 175     


Lys Pro Ser Ile Asn Thr Asp Lys Leu Lys Asn Ile Ser Ser Asn Tyr 
            180                 185                 190         


Cys Leu Gly Arg His Leu Pro Cys Ile Ser Leu His Pro Trp Leu Ser 
        195                 200                 205             


Ser Pro Cys Ser Ser Asp Ser Pro Pro Arg Pro Ser Ser Cys Leu Leu 
    210                 215                 220                 


Ile Pro Ser Pro Glu Asn Asn Ser Glu Arg Leu Leu Val Asp Thr Arg 
225                 230                 235                 240 


Arg Phe Leu Ile His His Glu Asn Arg Thr Phe Pro Ser Thr Gln Leu 
                245                 250                 255     


Pro His Gln Ser Pro Leu Gln Pro Leu Thr Ala Ala Ala Leu Ala Gly 
            260                 265                 270         


Ser Leu Gly Val Trp Val Gln Asp Thr Pro Phe Ser Thr Pro Ser His 
        275                 280                 285             


Leu Phe Thr Leu His Leu Gln Phe Cys Leu Ala Gln Gly Leu Phe Phe 
    290                 295                 300                 


Leu Cys Gly Ser Ser Thr Tyr Met Cys Leu Pro Ala Asn Trp Thr Gly 
305                 310                 315                 320 


Thr Cys Thr Leu Val Phe Leu Thr Pro Lys Ile Gln Phe Ala Asn Gly 
                325                 330                 335     


Thr Glu Glu Leu Pro Val Pro Leu Met Thr Pro Thr Gln Gln Lys Arg 
            340                 345                 350         


<210>  1752
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  1752

Leu Pro Leu Pro Ser Tyr Leu His His Thr Ile Asn Leu Thr His Ser 
1               5                   10                  15      


Leu Pro Ala Ala Ser Asn Pro Ser Leu Ala Asn Asn Cys Trp Leu Cys 
            20                  25                  30          


Ile Ser Leu Ser Ser Ser Ala Tyr Ile Ala Val Pro Thr Leu Gln Thr 
        35                  40                  45              


Asp Arg Ala Thr Ser Pro Val Ser Leu His Leu Arg Thr Ser Phe Asn 
    50                  55                  60                  


Ser Pro His Leu Tyr Pro Pro Glu Glu Leu Ile Tyr Phe Leu Asp Arg 
65                  70                  75                  80  


Ser Ser Lys Thr Ser Pro Asp Ile Ser His Gln Pro Ala Ala Ala Leu 
                85                  90                  95      


Leu His Ile Tyr Leu Lys Asn Leu Ser Pro Tyr Ile Asn Ser Thr Pro 
            100                 105                 110         


Pro Ile Phe Gly Pro Leu Thr Thr Gln Thr Thr Ile Pro Val Ala Ala 
        115                 120                 125             


Pro Leu Cys Ile Ser Arg Gln Arg Pro Thr Gly Ile Pro Leu Gly Asn 
    130                 135                 140                 


Ile Ser Pro Ser Arg Cys Ser Phe Thr Leu His Leu Gln Ser Pro Thr 
145                 150                 155                 160 


Thr His Val Thr Glu Thr Ile Gly Val Phe Gln Leu His Ile Ile Asp 
                165                 170                 175     


Lys Pro Ser Ile Asn Thr Asp Lys Leu Lys Asn Val Ser Ser Asn Tyr 
            180                 185                 190         


Cys Leu Gly Arg His Leu Pro Tyr Ile Ser Leu His Pro Trp Leu Pro 
        195                 200                 205             


Ser Pro Cys Ser Ser Asp Ser Pro Pro Arg Pro Ser Ser Cys Leu Leu 
    210                 215                 220                 


Thr Pro Ser Pro Gln Asn Asn Ser Glu Arg Leu Leu Val Asp Thr Gln 
225                 230                 235                 240 


Arg Phe Leu Ile His His Glu Asn Arg Thr Ser Ser Ser Met Gln Leu 
                245                 250                 255     


Ala His Gln Ser Pro Leu Gln Pro Leu Thr Ala Ala Ala Leu Ala Gly 
            260                 265                 270         


Ser Leu Gly Val Trp Val Gln Asp Thr Pro Phe Ser Thr Pro Ser His 
        275                 280                 285             


Pro Phe Ser Leu His Leu Gln Phe Cys Leu Thr Gln Gly Leu Phe Phe 
    290                 295                 300                 


Leu Cys Gly Ser Ser Thr Tyr Met Cys Leu Pro Ala Asn Trp Thr Gly 
305                 310                 315                 320 


Thr Cys Thr Leu Val Phe Leu Thr Pro Lys Ile Gln Phe Ala Asn Gly 
                325                 330                 335     


Thr Lys Glu Leu Pro Val Pro Leu Met Thr Leu Thr Pro Gln Lys Arg 
            340                 345                 350         


<210>  1753
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  1753

Thr Phe Leu Pro Val Leu Ala Ala Thr Glu Pro Ala Val Ser Val Pro 
1               5                   10                  15      


Ser Gly Asp Leu Ser Met Pro Val Lys Thr Arg Ala Glu Gly Glu Asp 
            20                  25                  30          


Asp Gly Phe Gly Glu Ala Gly Asp Pro Arg Arg Leu Leu Glu Arg Pro 
        35                  40                  45              


Trp Arg Phe Arg Gly Cys Leu Pro Gly Lys Gly Asn Arg Asp Val Gly 
    50                  55                  60                  


Phe Glu Gly Thr Glu Gly Pro Thr Ser Thr Arg Pro Glu Trp Val Trp 
65                  70                  75                  80  


Ser Cys Arg Cys Cys Leu Gly Cys Arg Ala Ser Thr Arg Glu Arg Val 
                85                  90                  95      


Thr Ser Pro Val Arg Ala Ala Gly Pro Gln Pro Arg Phe Thr Asp Arg 
            100                 105                 110         


Glu Thr Glu Ala Ala Ala Gly Thr Leu Ala His Met Gly Phe Ala Pro 
        115                 120                 125             


Pro Thr Ser Phe Ser His Phe Thr Asp Gln Glu Leu Arg Asp Cys Ser 
    130                 135                 140                 


Ser Leu Glu Cys Leu Gly Val Val Glu Gly Asp Pro His Val Leu Cys 
145                 150                 155                 160 


Ser Thr Leu Ser Leu Ser Arg Pro Ser Pro Ser Ala Thr Leu Thr 
                165                 170                 175 


<210>  1754
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  1754

Arg Val Gly Thr Tyr Ala Val Cys Trp Cys Ser Trp Asn Thr Gly Arg 
1               5                   10                  15      


Phe Thr Gly Cys Pro Ser Trp Lys Asp Phe Trp Lys Pro Val Gly Pro 
            20                  25                  30          


Ala Leu His Val Phe Asn Val Lys Cys Glu Ala Gln Arg Gly Leu Lys 
        35                  40                  45              


Leu Thr Gln Pro Phe Thr Val Ala Cys Lys Ile Asp Pro Val Leu Cys 
    50                  55                  60                  


Lys Ser Gly Leu Gly Phe Pro Pro Gln Leu Phe Thr Gly Cys Val Tyr 
65                  70                  75                  80  


Leu Ser Thr Tyr Thr Tyr Pro Trp Gln Ala Gln Ala Glu Cys Val Arg 
                85                  90                  95      


Cys Pro Arg Asp Ser Asn Arg Cys Lys Arg Ile Thr Pro Ser Ala Cys 
            100                 105                 110         


Leu 
    


<210>  1755
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  1755

Val Asn Phe Tyr Leu Pro Pro Glu Ser Ile Asp Phe Glu Phe Met Ala 
1               5                   10                  15      


His Asn Trp Ser Lys Gly Arg Ser Pro Ser Ser Thr Leu Gly Leu Ser 
            20                  25                  30          


Trp Phe Lys Ala Gly Phe Arg Phe Ser Asp Gly Trp Ser Met Phe Tyr 
        35                  40                  45              


Ser Phe Gly Leu Pro Gly Val Ala Leu Pro Gly Ser Pro Pro Arg Ser 
    50                  55                  60                  


His Leu Leu Pro Gly Thr Gln Ile Leu Ile Arg Ser Phe Gln Pro Cys 
65                  70                  75                  80  


Glu Ser Ala Lys His Ser Ala Arg Leu Ser Ser Leu Leu Thr Thr Thr 
                85                  90                  95      


Ser Tyr Ser Val Ser 
            100     


<210>  1756
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  1756

Val Asn Phe Tyr Leu Pro Pro Glu Ser Ile Asp Phe Glu Phe Met Ala 
1               5                   10                  15      


His Asn Trp Ser Lys Gly Arg Ser Pro Ser Ser Thr Leu Gly Leu Ser 
            20                  25                  30          


Trp Phe Lys Ala Gly Phe Arg Phe Ser Asp Gly Trp Ser Met Phe Tyr 
        35                  40                  45              


Ser Ser Gly Leu Pro Gly Val Ala Leu Pro Gly Ser Pro Pro Arg Ser 
    50                  55                  60                  


His Leu Leu Pro Gly Thr Gln Ile Leu Ile Arg Ser Phe Gln Pro Cys 
65                  70                  75                  80  


Glu Ser Ala Lys His Ser Ala Arg Leu Ser Ser Leu Leu Thr Thr Thr 
                85                  90                  95      


Ser Tyr Ser Val Ser 
            100     


<210>  1757
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1757

Ala Glu His Leu Pro His Arg Pro Ala Val Glu Lys Asp Val Pro Gly 
1               5                   10                  15      


Ala Gly Glu Val Leu Phe Met Cys Ser Trp Arg Ile Phe Pro Val Ala 
            20                  25                  30          


Ser Ala Ser Pro Ser Ser Ser Ile Ser Gly Leu Ala Gly His Ser Val 
        35                  40                  45              


Phe Leu Val Pro Gly Leu Ala Ala His Pro Gly Ser His Ser Asp Gln 
    50                  55                  60                  


Pro Pro Gly Val Pro Ser Arg Arg Lys Ser Arg Leu Glu Arg Trp Ser 
65                  70                  75                  80  


Pro Ser Val Ser Arg Ser Thr Ser Pro Pro Thr Glu Ala Pro Phe Cys 
                85                  90                  95      


Leu 
    


<210>  1758
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  1758

Ala Cys Val Val Val Ser Arg Asp Trp Leu Ser Leu Val Pro Ala Phe 
1               5                   10                  15      


Phe Tyr Ser Pro Pro Pro Gly Gly Ser Phe Ser Gly Ile Lys Arg Glu 
            20                  25                  30          


Ser Arg Arg Lys Arg Pro Ser Arg Asn Glu Ile Tyr Gly Gly Gly Val 
        35                  40                  45              


Leu Glu Gln Glu Val Arg Met Arg Arg Trp Ser Lys Thr Ala Ser Pro 
    50                  55                  60                  


Pro Val Ser Leu His His Arg Pro Leu Gly Pro Ala Arg Lys Pro 
65                  70                  75                  


<210>  1759
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  1759

Gly Thr Asp Val Ala Ala Pro Glu His Ile Ser Tyr Val Pro Gln Leu 
1               5                   10                  15      


Ser Asn Asp Thr Leu Ala Gly Arg Leu Thr Leu Ser Thr Phe Thr Leu 
            20                  25                  30          


Glu Gln Pro Leu Gly Gln Phe Ser Ser His Asn Ile Ser Asp Leu Asp 
        35                  40                  45              


Thr Ile Trp Leu Val Val Ala Leu Ser Asn Ala Thr Gln Ser Phe Thr 
    50                  55                  60                  


Ala Pro Arg Thr Asn Gln Asp Ile Pro Ala Pro Ala Asn Phe Ser Gln 
65                  70                  75                  80  


Arg Gly Tyr Tyr Leu Thr Leu Arg Ala Asn Arg Val Leu Tyr Gln Thr 
                85                  90                  95      


Arg Gly Gln Leu His Val Leu Arg Val Gly Asn Asp Thr His Cys Gln 
            100                 105                 110         


Pro Thr Lys Ile Gly Cys Asn His Pro Leu Pro Gly Pro Gly Pro Tyr 
        115                 120                 125             


Arg Val Lys Phe Leu Val Met Asn Asp Glu Gly Pro Val Ala Glu Thr 
    130                 135                 140                 


Lys Trp Ser Ser Asp Thr Arg Leu Gln Gln Ala Gln Ala Leu Arg Ala 
145                 150                 155                 160 


Val Pro Gly Pro Gln Ser Pro Gly Thr Val Val 
                165                 170     


<210>  1760
<211>  355
<212>  PRT
<213>  Homo Sapiens

<400>  1760

Met Thr Gly Ser Ala Ala Asp Thr His Arg Cys Pro His Pro Lys Gly 
1               5                   10                  15      


Ala Lys Gly Thr Arg Ser Arg Ser Ser His Ala Arg Pro Val Ser Leu 
            20                  25                  30          


Ala Thr Ser Gly Gly Ser Glu Glu Glu Asp Lys Asp Gly Gly Val Leu 
        35                  40                  45              


Phe His Val Asn Lys Ser Gly Phe Pro Ile Asp Ser His Thr Trp Glu 
    50                  55                  60                  


Arg Met Trp Met His Val Ala Lys Val His Pro Lys Gly Gly Glu Met 
65                  70                  75                  80  


Val Gly Ala Ile Arg Asn Ala Ala Phe Leu Ala Lys Pro Ser Ile Pro 
                85                  90                  95      


Gln Val Pro Asn Tyr Arg Leu Ser Met Thr Ile Pro Asp Trp Leu Gln 
            100                 105                 110         


Ala Ile Gln Asn Tyr Met Lys Thr Leu Gln Tyr Asn His Thr Gly Thr 
        115                 120                 125             


Gln Phe Phe Glu Ile Arg Lys Met Arg Pro Leu Ser Gly Leu Met Glu 
    130                 135                 140                 


Thr Ala Lys Glu Met Thr Arg Glu Ser Leu Pro Ile Lys Cys Leu Glu 
145                 150                 155                 160 


Ala Val Ile Leu Gly Ile Tyr Leu Thr Asn Gly Gln Pro Ser Ile Glu 
                165                 170                 175     


Arg Phe Pro Ile Ser Phe Lys Thr Tyr Phe Ser Gly Asn Tyr Phe His 
            180                 185                 190         


His Val Val Leu Gly Ile Tyr Cys Asn Gly Arg Tyr Gly Ser Leu Gly 
        195                 200                 205             


Met Ser Arg Arg Ala Glu Leu Met Asp Lys Pro Leu Thr Phe Arg Thr 
    210                 215                 220                 


Leu Ser Asp Leu Ile Phe Asp Phe Glu Asp Ser Tyr Lys Lys Tyr Leu 
225                 230                 235                 240 


His Thr Val Lys Lys Val Lys Ile Gly Leu Tyr Val Pro His Glu Pro 
                245                 250                 255     


His Ser Phe Gln Pro Ile Glu Trp Lys Gln Leu Val Leu Asn Val Ser 
            260                 265                 270         


Lys Met Leu Arg Ala Asp Ile Arg Lys Glu Leu Glu Lys Tyr Ala Arg 
        275                 280                 285             


Asp Met Arg Met Lys Ile Leu Lys Pro Ala Ser Ala His Ser Pro Thr 
    290                 295                 300                 


Gln Val Arg Ser Arg Gly Lys Ser Leu Ser Pro Arg Arg Arg Gln Ala 
305                 310                 315                 320 


Ser Pro Pro Arg Arg Leu Gly Arg Arg Glu Lys Ser Pro Ala Leu Pro 
                325                 330                 335     


Glu Lys Lys Val Ala Asp Leu Ser Thr Leu Asn Glu Val Gly Tyr Gln 
            340                 345                 350         


Ile Arg Ile 
        355 


<210>  1761
<211>  448
<212>  PRT
<213>  Homo Sapiens

<400>  1761

Leu Asp Thr Phe Ile Ala Ala Val Tyr Glu His Ala Val Ile Leu Pro 
1               5                   10                  15      


Asn Arg Thr Glu Thr Pro Val Ser Lys Glu Glu Ala Leu Leu Leu Met 
            20                  25                  30          


Asn Lys Asn Ile Asp Val Leu Glu Lys Ala Val Lys Leu Ala Ala Lys 
        35                  40                  45              


Gln Gly Ala His Ile Ile Val Thr Pro Glu Asp Gly Ile Tyr Gly Trp 
    50                  55                  60                  


Ile Phe Thr Arg Glu Ser Ile Tyr Pro Tyr Leu Glu Asp Ile Pro Asp 
65                  70                  75                  80  


Pro Gly Val Asn Trp Ile Pro Cys Arg Asp Pro Trp Arg Phe Gly Asn 
                85                  90                  95      


Thr Pro Val Gln Gln Arg Leu Ser Cys Leu Ala Lys Asp Asn Ser Ile 
            100                 105                 110         


Tyr Val Val Ala Asn Ile Gly Asp Lys Lys Pro Cys Asn Ala Ser Asp 
        115                 120                 125             


Ser Gln Cys Pro Pro Asp Gly Arg Tyr Gln Tyr Asn Thr Asp Val Val 
    130                 135                 140                 


Phe Asp Ser Gln Gly Lys Leu Leu Ala Arg Tyr His Lys Tyr Asn Leu 
145                 150                 155                 160 


Phe Ala Pro Glu Ile Gln Phe Asp Phe Pro Lys Asp Ser Glu Leu Val 
                165                 170                 175     


Thr Phe Asp Thr Pro Phe Gly Lys Phe Gly Ile Phe Thr Cys Phe Asp 
            180                 185                 190         


Ile Phe Ser His Asp Pro Ala Val Val Val Val Asp Glu Val Ser Ile 
        195                 200                 205             


Asp Ser Ile Leu Tyr Pro Thr Ala Trp Tyr Asn Thr Leu Pro Leu Leu 
    210                 215                 220                 


Ser Ala Val Pro Phe His Ser Ala Trp Ala Lys Ala Met Gly Val Asn 
225                 230                 235                 240 


Leu Leu Ala Ala Asn Thr His Asn Thr Ser Met His Met Thr Gly Ser 
                245                 250                 255     


Gly Ile Tyr Ala Pro Glu Ala Val Lys Val Tyr His Tyr Asp Met Glu 
            260                 265                 270         


Thr Glu Ser Gly Gln Leu Leu Leu Ser Glu Leu Lys Ser Arg Pro Arg 
        275                 280                 285             


Arg Glu Pro Thr Tyr Pro Ala Ala Val Asp Trp His Ala Tyr Ala Ser 
    290                 295                 300                 


Ser Val Lys Pro Phe Ser Ser Glu Gln Ser Asp Phe Leu Gly Met Ile 
305                 310                 315                 320 


Tyr Phe Asp Glu Phe Thr Phe Thr Lys Leu Lys Arg Asn Thr Gly Asn 
                325                 330                 335     


Tyr Thr Ala Cys Gln Lys Asp Leu Cys Cys His Leu Thr Tyr Lys Met 
            340                 345                 350         


Ser Glu Lys Arg Thr Asp Glu Ile Tyr Ala Leu Gly Ala Phe Asp Gly 
        355                 360                 365             


Leu His Thr Val Glu Gly Gln Tyr Tyr Leu Gln Ile Cys Ala Leu Leu 
    370                 375                 380                 


Lys Cys Gln Thr Thr Asp Leu Glu Thr Cys Gly Glu Pro Val Gly Ser 
385                 390                 395                 400 


Ala Phe Thr Lys Phe Glu Asp Phe Ser Leu Ser Gly Thr Phe Gly Thr 
                405                 410                 415     


Arg Tyr Val Phe Pro Gln Ile Ile Leu Ser Gly Ser Gln Leu Ala Pro 
            420                 425                 430         


Glu Arg His Tyr Glu Ile Ser Arg Asp Gly Arg Leu Arg Ser Arg Ser 
        435                 440                 445             


<210>  1762
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  1762

Ser Pro Lys Gln Arg Val Leu Lys Tyr Ile Leu Glu Pro Pro Pro Cys 
1               5                   10                  15      


Ile Ser Ala Pro Glu Asn Cys Thr His Leu Cys Thr Met Gln Glu Asp 
            20                  25                  30          


Cys Glu Lys Gly Phe Gln Cys Cys Ser Ser Phe Cys Gly Ile Val Cys 
        35                  40                  45              


Ser Ser Glu Thr Phe Gln Lys Arg Asn Arg Ile Lys His Lys Gly Ser 
    50                  55                  60                  


Glu Val Ile Met Pro Ala Asn 
65                  70      


<210>  1763
<211>  203
<212>  PRT
<213>  Homo Sapiens

<400>  1763

Met Leu Thr Lys Lys Ile Lys His Lys Pro Gly Leu Cys Pro Lys Glu 
1               5                   10                  15      


Arg Leu Thr Cys Thr Thr Glu Leu Pro Asp Ser Cys Asn Thr Asp Phe 
            20                  25                  30          


Asp Cys Lys Glu Tyr Gln Lys Cys Cys Phe Phe Ala Cys Gln Lys Lys 
        35                  40                  45              


Cys Met Asp Pro Phe Gln Glu Pro Cys Met Leu Pro Val Arg His Gly 
    50                  55                  60                  


Asn Cys Asn His Glu Ala Gln Arg Trp His Phe Asp Phe Lys Asn Tyr 
65                  70                  75                  80  


Arg Cys Thr Pro Phe Lys Tyr Arg Gly Cys Glu Gly Asn Ala Asn Asn 
                85                  90                  95      


Phe Leu Asn Glu Asp Ala Cys Arg Thr Ala Cys Met Leu Ile Val Lys 
            100                 105                 110         


Asp Gly Gln Cys Pro Leu Phe Pro Phe Thr Glu Arg Lys Glu Cys Pro 
        115                 120                 125             


Pro Ser Cys His Ser Asp Ile Asp Cys Pro Gln Thr Asp Lys Cys Cys 
    130                 135                 140                 


Glu Ser Arg Cys Gly Phe Val Cys Ala Arg Ala Trp Thr Val Lys Lys 
145                 150                 155                 160 


Gly Phe Cys Pro Arg Lys Pro Leu Leu Cys Thr Lys Ile Asp Lys Pro 
                165                 170                 175     


Lys Cys Leu Gln Asp Glu Glu Cys Pro Leu Val Glu Lys Cys Cys Ser 
            180                 185                 190         


His Cys Gly Leu Lys Cys Met Asp Pro Arg Arg 
        195                 200             


<210>  1764
<211>  345
<212>  PRT
<213>  Homo Sapiens

<400>  1764

Thr Ala Leu Ser Pro Ala Pro Thr Thr Met Asp Phe Thr Pro Ala Pro 
1               5                   10                  15      


Leu Glu Asp Thr Ser Ser Arg Pro Gln Phe Cys Lys Trp Pro Cys Glu 
            20                  25                  30          


Cys Pro Pro Ser Pro Pro Arg Cys Pro Leu Gly Val Ser Leu Ile Thr 
        35                  40                  45              


Asp Gly Cys Glu Cys Cys Lys Met Cys Ala Gln Gln Leu Gly Asp Asn 
    50                  55                  60                  


Cys Thr Glu Ala Ala Ile Cys Asp Pro His Arg Gly Leu Tyr Cys Asp 
65                  70                  75                  80  


Tyr Ser Gly Asp Arg Pro Arg Tyr Ala Ile Gly Val Cys Ala Gln Val 
                85                  90                  95      


Val Gly Val Gly Cys Val Leu Asp Gly Val Arg Tyr Asn Asn Gly Gln 
            100                 105                 110         


Ser Phe Gln Pro Asn Cys Lys Tyr Asn Cys Thr Cys Ile Asp Gly Ala 
        115                 120                 125             


Val Gly Cys Thr Pro Leu Cys Leu Arg Val Arg Pro Pro Arg Leu Trp 
    130                 135                 140                 


Cys Pro His Pro Arg Arg Val Ser Ile Pro Gly His Cys Cys Glu Gln 
145                 150                 155                 160 


Trp Val Cys Glu Asp Asp Ala Lys Arg Pro Arg Lys Thr Ala Pro Arg 
                165                 170                 175     


Asp Thr Gly Ala Phe Asp Ala Val Gly Glu Val Glu Ala Trp His Arg 
            180                 185                 190         


Asn Cys Ile Ala Tyr Thr Ser Pro Trp Ser Pro Cys Ser Thr Ser Cys 
        195                 200                 205             


Gly Leu Gly Val Ser Thr Arg Ile Ser Asn Val Asn Ala Gln Cys Trp 
    210                 215                 220                 


Pro Glu Gln Glu Ser Arg Leu Cys Asn Leu Arg Pro Cys Asp Val Asp 
225                 230                 235                 240 


Ile His Thr Leu Ile Lys Ala Gly Lys Lys Cys Leu Ala Val Tyr Gln 
                245                 250                 255     


Pro Glu Ala Ser Met Asn Phe Thr Leu Ala Gly Cys Ile Ser Thr Arg 
            260                 265                 270         


Ser Tyr Gln Pro Lys Tyr Cys Gly Val Cys Met Asp Asn Arg Cys Cys 
        275                 280                 285             


Ile Pro Tyr Lys Ser Lys Thr Ile Asp Val Ser Phe Gln Cys Pro Asp 
    290                 295                 300                 


Gly Leu Gly Phe Ser Arg Gln Val Leu Trp Ile Asn Ala Cys Phe Cys 
305                 310                 315                 320 


Asn Leu Ser Cys Arg Asn Pro Asn Asp Ile Phe Ala Asp Leu Glu Ser 
                325                 330                 335     


Tyr Pro Asp Phe Ser Glu Ile Ala Asn 
            340                 345 


<210>  1765
<211>  334
<212>  PRT
<213>  Homo Sapiens

<400>  1765

Gly Tyr Pro Ile Trp Trp Ser Leu Ala Leu Gly Gln Gln Tyr Thr Ser 
1               5                   10                  15      


Leu Gly Ser Gln Pro Leu Leu Cys Gly Ser Ile Pro Gly Leu Val Pro 
            20                  25                  30          


Lys Gln Leu Arg Phe Cys Arg Asn Tyr Ile Glu Ile Met Pro Ser Val 
        35                  40                  45              


Ala Glu Gly Val Lys Leu Gly Ile Gln Glu Cys Gln His Gln Phe Arg 
    50                  55                  60                  


Gly Arg Arg Trp Asn Cys Thr Thr Ile Asp Asp Ser Leu Ala Ile Phe 
65                  70                  75                  80  


Gly Pro Val Leu Asp Lys Ala Thr Arg Glu Ser Ala Phe Val His Ala 
                85                  90                  95      


Ile Ala Ser Ala Gly Val Ala Phe Ala Val Thr Arg Ser Cys Ala Glu 
            100                 105                 110         


Gly Thr Ser Thr Ile Cys Gly Cys Asp Ser His His Lys Gly Pro Pro 
        115                 120                 125             


Gly Glu Gly Trp Lys Trp Gly Gly Cys Ser Glu Asp Ala Asp Phe Gly 
    130                 135                 140                 


Val Leu Val Ser Arg Glu Phe Ala Asp Ala Arg Glu Asn Arg Pro Asp 
145                 150                 155                 160 


Ala Arg Ser Ala Met Asn Lys His Asn Asn Glu Ala Gly Arg Thr Thr 
                165                 170                 175     


Ile Leu Asp His Met His Leu Lys Cys Lys Cys His Gly Leu Ser Gly 
            180                 185                 190         


Ser Cys Glu Val Lys Thr Cys Trp Trp Ala Gln Pro Asp Phe Arg Ala 
        195                 200                 205             


Ile Gly Asp Phe Leu Lys Asp Lys Tyr Asp Ser Ala Ser Glu Met Val 
    210                 215                 220                 


Val Glu Lys His Arg Glu Ser Arg Gly Trp Val Glu Thr Leu Arg Ala 
225                 230                 235                 240 


Lys Tyr Ser Leu Phe Lys Pro Pro Thr Glu Arg Asp Leu Val Tyr Tyr 
                245                 250                 255     


Glu Asn Ser Pro Asn Phe Cys Glu Pro Asn Pro Glu Thr Gly Ser Phe 
            260                 265                 270         


Gly Thr Arg Asp Arg Thr Cys Asn Val Thr Ser His Gly Ile Asp Gly 
        275                 280                 285             


Cys Asp Leu Leu Cys Cys Gly Arg Gly His Asn Thr Arg Thr Glu Lys 
    290                 295                 300                 


Arg Lys Glu Lys Cys His Cys Ile Phe His Trp Cys Cys Tyr Val Ser 
305                 310                 315                 320 


Cys Gln Glu Cys Ile Arg Ile Tyr Asp Val His Thr Cys Lys 
                325                 330                 


<210>  1766
<211>  341
<212>  PRT
<213>  Homo Sapiens

<400>  1766

Leu Trp Trp Ala Val Gly Ser Pro Leu Val Met Asp Pro Thr Ser Ile 
1               5                   10                  15      


Cys Arg Lys Ala Arg Arg Leu Ala Gly Arg Gln Ala Glu Leu Cys Gln 
            20                  25                  30          


Ala Glu Pro Glu Val Val Ala Glu Leu Ala Arg Gly Ala Arg Leu Gly 
        35                  40                  45              


Val Arg Glu Cys Gln Phe Gln Phe Arg Phe Arg Arg Trp Asn Cys Ser 
    50                  55                  60                  


Ser His Ser Lys Ala Phe Gly Arg Ile Leu Gln Gln Asp Ile Arg Glu 
65                  70                  75                  80  


Thr Ala Phe Val Phe Ala Ile Thr Ala Ala Gly Ala Ser His Ala Val 
                85                  90                  95      


Thr Gln Ala Cys Ser Met Gly Glu Leu Leu Gln Cys Gly Cys Gln Ala 
            100                 105                 110         


Pro Arg Gly Arg Ala Pro Pro Arg Pro Ser Gly Leu Pro Gly Thr Pro 
        115                 120                 125             


Gly Pro Pro Gly Pro Ala Gly Ser Pro Glu Gly Ser Ala Ala Trp Glu 
    130                 135                 140                 


Trp Gly Gly Cys Gly Asp Asp Val Asp Phe Gly Asp Glu Lys Ser Arg 
145                 150                 155                 160 


Leu Phe Met Asp Ala Arg His Lys Arg Gly Arg Gly Asp Ile Arg Ala 
                165                 170                 175     


Leu Val Gln Leu His Asn Asn Glu Ala Gly Arg Leu Ala Val Arg Ser 
            180                 185                 190         


His Thr Arg Thr Glu Cys Lys Cys His Gly Leu Ser Gly Ser Cys Ala 
        195                 200                 205             


Leu Arg Thr Cys Trp Gln Lys Leu Pro Pro Phe Arg Glu Val Gly Ala 
    210                 215                 220                 


Arg Leu Leu Glu Arg Phe His Gly Ala Ser Arg Val Met Gly Thr Asn 
225                 230                 235                 240 


Asp Gly Lys Ala Leu Leu Pro Ala Val Arg Thr Leu Lys Pro Pro Gly 
                245                 250                 255     


Arg Ala Asp Leu Leu Tyr Ala Ala Asp Ser Pro Asp Phe Cys Ala Pro 
            260                 265                 270         


Asn Arg Arg Thr Gly Ser Pro Gly Thr Arg Gly Arg Ala Cys Asn Ser 
        275                 280                 285             


Ser Ala Pro Asp Leu Ser Gly Cys Asp Leu Leu Cys Cys Gly Arg Gly 
    290                 295                 300                 


His Arg Gln Glu Ser Val Gln Leu Glu Glu Asn Cys Leu Cys Arg Phe 
305                 310                 315                 320 


His Trp Cys Cys Val Val Gln Cys His Arg Cys Arg Val Arg Lys Glu 
                325                 330                 335     


Leu Ser Leu Cys Leu 
            340     


<210>  1767
<211>  327
<212>  PRT
<213>  Homo Sapiens

<400>  1767

Val Asn Asn Phe Leu Ile Thr Gly Pro Lys Ala Tyr Leu Thr Tyr Thr 
1               5                   10                  15      


Thr Ser Val Ala Leu Gly Ala Gln Ser Gly Ile Glu Glu Cys Lys Phe 
            20                  25                  30          


Gln Phe Ala Trp Glu Arg Trp Asn Cys Pro Glu Asn Ala Leu Gln Leu 
        35                  40                  45              


Ser Thr His Asn Arg Leu Arg Ser Ala Thr Arg Glu Thr Ser Phe Ile 
    50                  55                  60                  


His Ala Ile Ser Ser Ala Gly Val Met Tyr Ile Ile Thr Lys Asn Cys 
65                  70                  75                  80  


Ser Met Gly Asp Phe Glu Asn Cys Gly Cys Asp Gly Ser Asn Asn Gly 
                85                  90                  95      


Lys Thr Gly Gly His Gly Trp Ile Trp Gly Gly Cys Ser Asp Asn Val 
            100                 105                 110         


Glu Phe Gly Glu Arg Ile Ser Lys Leu Phe Val Asp Ser Leu Glu Lys 
        115                 120                 125             


Gly Lys Asp Ala Arg Ala Leu Met Asn Leu His Asn Asn Arg Ala Gly 
    130                 135                 140                 


Arg Leu Ala Val Arg Ala Thr Met Lys Arg Thr Cys Lys Cys His Gly 
145                 150                 155                 160 


Ile Ser Gly Ser Cys Ser Ile Gln Thr Cys Trp Leu Gln Leu Ala Glu 
                165                 170                 175     


Phe Arg Glu Met Gly Asp Tyr Leu Lys Ala Lys Tyr Asp Gln Ala Leu 
            180                 185                 190         


Lys Ile Glu Met Asp Lys Arg Gln Leu Arg Ala Gly Asn Ser Ala Glu 
        195                 200                 205             


Gly His Trp Val Pro Ala Glu Ala Phe Leu Pro Ser Ala Glu Ala Glu 
    210                 215                 220                 


Leu Ile Phe Leu Glu Glu Ser Pro Asp Tyr Cys Thr Cys Asn Ser Ser 
225                 230                 235                 240 


Leu Gly Ile Tyr Gly Thr Glu Gly Arg Glu Cys Leu Gln Asn Ser His 
                245                 250                 255     


Asn Thr Ser Arg Trp Glu Arg Arg Ser Cys Gly Arg Leu Cys Thr Glu 
            260                 265                 270         


Cys Gly Leu Gln Val Glu Glu Arg Lys Thr Glu Val Ile Ser Ser Cys 
        275                 280                 285             


Asn Cys Lys Phe Gln Trp Cys Cys Thr Val Lys Cys Asp Gln Cys Arg 
    290                 295                 300                 


His Val Val Ser Lys Tyr Tyr Cys Ala Arg Ser Pro Gly Ser Ala Gln 
305                 310                 315                 320 


Ser Leu Gly Lys Gly Ser Ala 
                325         


<210>  1768
<211>  335
<212>  PRT
<213>  Homo Sapiens

<400>  1768

Ser Tyr Phe Gly Leu Thr Gly Arg Glu Val Leu Thr Pro Phe Pro Gly 
1               5                   10                  15      


Leu Gly Thr Ala Ala Ala Pro Ala Gln Gly Gly Ala His Leu Lys Gln 
            20                  25                  30          


Cys Asp Leu Leu Lys Leu Ser Arg Arg Gln Lys Gln Leu Cys Arg Arg 
        35                  40                  45              


Glu Pro Gly Leu Ala Glu Thr Leu Arg Asp Ala Ala His Leu Gly Leu 
    50                  55                  60                  


Leu Glu Cys Gln Phe Gln Phe Arg His Glu Arg Trp Asn Cys Ser Leu 
65                  70                  75                  80  


Glu Gly Arg Met Gly Leu Leu Lys Arg Gly Phe Lys Glu Thr Ala Phe 
                85                  90                  95      


Leu Tyr Ala Val Ser Ser Ala Ala Leu Thr His Thr Leu Ala Arg Ala 
            100                 105                 110         


Cys Ser Ala Gly Arg Met Glu Arg Cys Thr Cys Asp Asp Ser Pro Gly 
        115                 120                 125             


Leu Glu Ser Arg Gln Ala Trp Gln Trp Gly Val Cys Gly Asp Asn Leu 
    130                 135                 140                 


Lys Tyr Ser Thr Lys Phe Leu Ser Asn Phe Leu Gly Ser Lys Arg Gly 
145                 150                 155                 160 


Asn Lys Asp Leu Arg Ala Arg Ala Asp Ala His Asn Thr His Val Gly 
                165                 170                 175     


Ile Lys Ala Val Lys Ser Gly Leu Arg Thr Thr Cys Lys Cys His Gly 
            180                 185                 190         


Val Ser Gly Ser Cys Ala Val Arg Thr Cys Trp Lys Gln Leu Ser Pro 
        195                 200                 205             


Phe Arg Glu Thr Gly Gln Val Leu Lys Leu Arg Tyr Asp Ser Ala Val 
    210                 215                 220                 


Lys Val Ser Ser Ala Thr Asn Glu Ala Leu Gly Arg Leu Glu Leu Trp 
225                 230                 235                 240 


Ala Pro Ala Arg Gln Gly Ser Leu Thr Lys Gly Leu Ala Pro Arg Ser 
                245                 250                 255     


Gly Asp Leu Val Tyr Met Glu Asp Ser Pro Ser Phe Cys Arg Pro Ser 
            260                 265                 270         


Lys Tyr Ser Pro Gly Thr Ala Gly Arg Val Cys Ser Arg Glu Ala Ser 
        275                 280                 285             


Cys Ser Ser Leu Cys Cys Gly Arg Gly Tyr Asp Thr Gln Ser Arg Leu 
    290                 295                 300                 


Val Ala Phe Ser Cys His Cys Gln Val Gln Trp Cys Cys Tyr Val Glu 
305                 310                 315                 320 


Cys Gln Gln Cys Val Gln Glu Glu Leu Val Tyr Thr Cys Lys His 
                325                 330                 335 


<210>  1769
<211>  365
<212>  PRT
<213>  Homo Sapiens

<400>  1769

Gln Pro Leu Trp Leu Leu Gln Gly Gly Ala Ser His Pro Glu Thr Ser 
1               5                   10                  15      


Val Gln Pro Val Leu Val Glu Cys Gln Glu Ala Thr Leu Met Val Met 
            20                  25                  30          


Val Ser Lys Asp Leu Phe Gly Thr Gly Lys Leu Ile Arg Ala Ala Asp 
        35                  40                  45              


Leu Thr Leu Gly Pro Glu Ala Cys Glu Pro Leu Val Ser Met Asp Thr 
    50                  55                  60                  


Glu Asp Val Val Arg Phe Glu Val Gly Leu His Glu Cys Gly Asn Ser 
65                  70                  75                  80  


Met Gln Val Thr Asp Asp Ala Leu Val Tyr Ser Thr Phe Leu Leu His 
                85                  90                  95      


Asp Pro Arg Pro Val Gly Asn Leu Ser Ile Val Arg Thr Asn Arg Ala 
            100                 105                 110         


Glu Ile Pro Ile Glu Cys Arg Tyr Pro Arg Gln Gly Asn Val Ser Ser 
        115                 120                 125             


Gln Ala Ile Leu Pro Thr Trp Leu Pro Phe Arg Thr Thr Val Phe Ser 
    130                 135                 140                 


Glu Glu Lys Leu Thr Phe Ser Leu Arg Leu Met Glu Glu Asn Trp Asn 
145                 150                 155                 160 


Ala Glu Lys Arg Ser Pro Thr Phe His Leu Gly Asp Ala Ala His Leu 
                165                 170                 175     


Gln Ala Glu Ile His Thr Gly Ser His Val Pro Leu Arg Leu Phe Val 
            180                 185                 190         


Asp His Cys Val Ala Thr Pro Thr Pro Asp Gln Asn Ala Ser Pro Tyr 
        195                 200                 205             


His Thr Ile Val Asp Phe His Gly Cys Leu Val Asp Gly Leu Thr Asp 
    210                 215                 220                 


Ala Ser Ser Ala Phe Lys Val Pro Arg Pro Gly Pro Asp Thr Leu Gln 
225                 230                 235                 240 


Phe Thr Val Asp Val Phe His Phe Ala Asn Asp Ser Arg Asn Met Ile 
                245                 250                 255     


Tyr Ile Thr Cys His Leu Lys Val Thr Leu Ala Glu Gln Asp Pro Asp 
            260                 265                 270         


Glu Leu Asn Lys Ala Cys Ser Phe Ser Lys Pro Ser Asn Ser Trp Phe 
        275                 280                 285             


Pro Val Glu Gly Ser Ala Asp Ile Cys Gln Cys Cys Asn Lys Gly Asp 
    290                 295                 300                 


Cys Gly Thr Pro Ser His Ser Arg Arg Gln Pro His Val Met Ser Gln 
305                 310                 315                 320 


Trp Ser Arg Ser Ala Ser Arg Asn Arg Arg His Val Thr Glu Glu Ala 
                325                 330                 335     


Asp Val Thr Val Gly Pro Leu Ile Phe Leu Asp Arg Arg Gly Asp His 
            340                 345                 350         


Glu Val Glu Gln Trp Ala Leu Pro Ser Asp Thr Ser Val 
        355                 360                 365 


<210>  1770
<211>  487
<212>  PRT
<213>  Homo Sapiens

<400>  1770

Gly Gln His Lys Pro Glu Ala Pro Asp Tyr Ser Ser Val Leu His Cys 
1               5                   10                  15      


Gly Pro Trp Ser Phe Gln Phe Ala Val Asn Leu Asn Gln Glu Ala Thr 
            20                  25                  30          


Ser Pro Pro Val Leu Ile Ala Trp Asp Asn Gln Gly Leu Leu His Glu 
        35                  40                  45              


Leu Gln Asn Asp Ser Asp Cys Gly Thr Trp Ile Arg Lys Gly Pro Gly 
    50                  55                  60                  


Ser Ser Val Val Leu Glu Ala Thr Tyr Ser Ser Cys Tyr Val Thr Glu 
65                  70                  75                  80  


Trp Asp Ser His Tyr Ile Met Pro Val Gly Val Glu Gly Ala Gly Ala 
                85                  90                  95      


Ala Glu His Lys Val Val Thr Glu Arg Lys Leu Leu Lys Cys Pro Met 
            100                 105                 110         


Asp Leu Leu Ala Arg Asp Ala Pro Asp Thr Asp Trp Cys Asp Ser Ile 
        115                 120                 125             


Pro Ala Arg Asp Arg Leu Pro Cys Ala Pro Ser Pro Ile Ser Arg Gly 
    130                 135                 140                 


Asp Cys Glu Gly Leu Gly Cys Cys Tyr Ser Ser Glu Glu Val Asn Ser 
145                 150                 155                 160 


Cys Tyr Tyr Gly Asn Thr Val Thr Leu His Cys Thr Arg Glu Gly His 
                165                 170                 175     


Phe Ser Ile Ala Val Ser Arg Asn Val Thr Ser Pro Pro Leu Leu Leu 
            180                 185                 190         


Asp Ser Val Arg Leu Ala Leu Arg Asn Asp Ser Ala Cys Asn Pro Val 
        195                 200                 205             


Met Ala Thr Gln Ala Phe Val Leu Phe Gln Phe Pro Phe Thr Ser Cys 
    210                 215                 220                 


Gly Thr Thr Arg Gln Ile Thr Gly Asp Arg Ala Val Tyr Glu Asn Glu 
225                 230                 235                 240 


Leu Val Ala Thr Arg Asp Val Lys Asn Gly Ser Arg Gly Ser Val Thr 
                245                 250                 255     


Arg Asp Ser Ile Phe Arg Leu His Val Ser Cys Ser Tyr Ser Val Ser 
            260                 265                 270         


Ser Asn Ser Leu Pro Ile Asn Val Gln Val Phe Thr Leu Pro Pro Pro 
        275                 280                 285             


Phe Pro Glu Thr Gln Pro Gly Pro Leu Thr Leu Glu Leu Gln Ile Ala 
    290                 295                 300                 


Lys Asp Lys Asn Tyr Gly Ser Tyr Tyr Gly Val Gly Asp Tyr Pro Val 
305                 310                 315                 320 


Val Lys Leu Leu Arg Asp Pro Ile Tyr Val Glu Val Ser Ile Leu His 
                325                 330                 335     


Arg Thr Asp Pro Tyr Leu Gly Leu Leu Leu Gln Gln Cys Trp Ala Thr 
            340                 345                 350         


Pro Ser Thr Asp Pro Leu Ser Gln Pro Gln Trp Pro Ile Leu Val Lys 
        355                 360                 365             


Gly Cys Pro Tyr Ile Gly Asp Asn Tyr Gln Thr Gln Leu Ile Pro Val 
    370                 375                 380                 


Gln Lys Ala Leu Asp Leu Pro Phe Pro Ser His His Gln Arg Phe Ser 
385                 390                 395                 400 


Ile Phe Thr Phe Ser Phe Val Asn Pro Thr Val Glu Lys Gln Ala Leu 
                405                 410                 415     


Arg Gly Pro Val His Leu His Cys Ser Val Ser Val Cys Gln Pro Ala 
            420                 425                 430         


Glu Thr Pro Ser Cys Val Val Thr Cys Pro Asp Leu Ser Arg Arg Arg 
        435                 440                 445             


Asn Phe Asp Asn Ser Ser Gln Asn Thr Thr Ala Ser Val Ser Ser Lys 
    450                 455                 460                 


Gly Pro Met Ile Leu Leu Gln Ala Thr Lys Asp Pro Pro Glu Lys Leu 
465                 470                 475                 480 


Arg Val Pro Val Asp Ser Lys 
                485         


<210>  1771
<211>  267
<212>  PRT
<213>  Homo Sapiens

<400>  1771

Ile Leu Gly Gly Val Pro Ala Pro Glu Arg Lys Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Val His Tyr Ala Gly Leu His Val Cys Gly Gly Ser Ile Leu Asn 
            20                  25                  30          


Glu Tyr Trp Val Leu Ser Ala Ala His Cys Phe His Arg Asp Lys Asn 
        35                  40                  45              


Ile Lys Ile Tyr Asp Met Tyr Val Gly Leu Val Asn Leu Arg Val Asp 
    50                  55                  60                  


Gly Asn His Thr Gln Trp Tyr Glu Val Asn Arg Val Ile Leu His Pro 
65                  70                  75                  80  


Thr Tyr Glu Met Tyr His Pro Ile Gly Gly Asp Val Ala Leu Val Gln 
                85                  90                  95      


Leu Lys Thr Arg Ile Val Phe Ser Glu Ser Val Leu Pro Val Cys Leu 
            100                 105                 110         


Ala Thr Pro Glu Val Asn Leu Thr Ser Ala Asn Cys Trp Ala Thr Gly 
        115                 120                 125             


Trp Gly Leu Val Ser Lys Gln Gly Glu Thr Ser Asp Glu Leu Gln Glu 
    130                 135                 140                 


Val Gln Leu Pro Leu Ile Leu Glu Pro Trp Cys His Leu Leu Tyr Gly 
145                 150                 155                 160 


His Met Ser Tyr Ile Met Pro Asp Met Leu Cys Ala Gly Asp Ile Leu 
                165                 170                 175     


Asn Ala Lys Thr Val Cys Glu Gly Asp Ser Gly Gly Pro Leu Val Cys 
            180                 185                 190         


Glu Phe Asn Arg Ser Trp Leu Gln Ile Gly Ile Val Ser Trp Gly Arg 
        195                 200                 205             


Gly Cys Ser Asn Pro Leu Tyr Pro Gly Val Tyr Ala Ser Val Ser Tyr 
    210                 215                 220                 


Phe Ser Lys Trp Ile Cys Asp Asn Ile Glu Ile Thr Pro Thr Pro Ala 
225                 230                 235                 240 


Gln Pro Ala Pro Ala Leu Ser Pro Ala Leu Gly Pro Thr Leu Ser Val 
                245                 250                 255     


Leu Met Ala Met Leu Ala Gly Trp Ser Val Leu 
            260                 265         


<210>  1772
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  1772

Ser Leu Ser Pro Thr Lys Tyr Asn Leu Leu Glu Leu Lys Glu Ser Cys 
1               5                   10                  15      


Ile Arg Asn Gln Asp Cys Glu Thr Gly Cys Cys Gln Arg Ala Pro Asp 
            20                  25                  30          


Asn Cys Glu Ser His Cys Ala Glu Lys Gly Ser Glu Gly Ser Leu Cys 
        35                  40                  45              


Gln Thr Gln Val Phe Phe Gly Gln Tyr Arg Ala Cys Pro Cys Leu Arg 
    50                  55                  60                  


Asn Leu Thr Cys Ile Tyr Ser Lys Asn Glu Lys Trp Leu Ser Ile Ala 
65                  70                  75                  80  


Tyr Gly Arg Cys Gln Lys Ile Gly Arg Gln Lys Leu Ala Lys Lys Met 
                85                  90                  95      


Phe Phe 
        


<210>  1773
<211>  992
<212>  PRT
<213>  Homo Sapiens

<400>  1773

Leu Arg Gly Ser Arg Lys Leu Thr Ala Ala Ala Pro Gly Ala Val Pro 
1               5                   10                  15      


His Thr Ser Thr Glu Thr Gln Ala Ser Arg Cys Lys Lys Gly Phe Ser 
            20                  25                  30          


Gln Asp Lys Gln Cys Phe Leu Leu Ser Gly Asn Ala Gln Glu Thr Arg 
        35                  40                  45              


Lys Val Lys Glu Ser Met Glu Thr His Phe Gly Ser His Gly Arg Arg 
    50                  55                  60                  


Ala Ile Leu Tyr Arg Pro Pro Phe Tyr Ser Lys Thr Glu Leu Gln Leu 
65                  70                  75                  80  


His Gln His Ile Leu Thr Gln His Gly Tyr Thr Val Val Ile Ala Glu 
                85                  90                  95      


Glu Arg Leu Asn Ala Gly Leu Gly Pro Gly Leu Leu Glu Gln Gly Asp 
            100                 105                 110         


Leu Gly Ser Trp Asp Leu Leu Ile Cys Leu Ser Ser Lys Lys Ala Glu 
        115                 120                 125             


Gly Thr Pro Cys Ile Ser Lys Glu Val Met Cys Gln Leu Gly Leu His 
    130                 135                 140                 


Gln Lys Ala Asn Arg Leu Pro Glu Ile Gln Gln Pro Leu Cys Arg Lys 
145                 150                 155                 160 


Glu Gly Leu Cys Gln Ile Val Arg Arg Phe Pro Glu Leu Gln Leu Pro 
                165                 170                 175     


Val Ser Pro Ser Val Cys Leu Asp Gln Gly Met Gln Leu Lys Pro Ser 
            180                 185                 190         


Thr Ser Ser His Leu Leu Lys Thr Val Lys Pro Arg Val Trp Lys Pro 
        195                 200                 205             


Gly Asp Trp Ser Arg Glu Gln Leu Asn Glu Thr Thr Val Leu Ala Pro 
    210                 215                 220                 


His Glu Thr Ile Phe Arg Ala Glu Asp Leu Ser Val Ile Leu Lys Ala 
225                 230                 235                 240 


Tyr Val Leu Val Thr Ser Leu Thr Pro Leu Arg Ala Phe Ile His Ser 
                245                 250                 255     


Thr Gly Thr Val Trp Asn Pro Pro Lys Lys Lys Arg Phe Thr Val Lys 
            260                 265                 270         


Leu Gln Thr Phe Phe Glu Thr Phe Leu Arg Ala Ser Ser Pro Gln Gln 
        275                 280                 285             


Ala Phe Asp Ile Met Lys Glu Ala Ile Gly Lys Leu Leu Leu Ala Ala 
    290                 295                 300                 


Glu Val Phe Ser Glu Thr Ser Thr Leu Gly Pro Lys Thr Phe His Arg 
305                 310                 315                 320 


Cys Arg Phe Cys Phe Gln Leu Leu Thr Phe Asp Ile Gly Tyr Gly Ser 
                325                 330                 335     


Phe Met Tyr Pro Val Val Leu Gln Val His Glu His Leu Asn Phe Gln 
            340                 345                 350         


Asp Tyr Asp Asn Met Asp Phe Glu Asp Gln Asn Thr Glu Glu Phe Leu 
        355                 360                 365             


Leu Asn Asp Thr Phe Asn Phe Leu Phe Pro Asn Glu Ser Ser Leu Ser 
    370                 375                 380                 


Ile Phe Ser Glu Ile Phe Gln Arg Leu Tyr Arg Ser Asp Val Phe Lys 
385                 390                 395                 400 


Gly Glu Asn Tyr Gln Lys Glu Leu Asn Gln Cys Leu Ser Leu Glu Glu 
                405                 410                 415     


Ile Asn Ser Ile Met Thr Phe Ile Lys Glu Leu Gly Ser Leu Gly Gln 
            420                 425                 430         


Phe Gln Leu Leu Phe Pro Ser Thr Thr Pro Gly Ile Gln Ser Leu Met 
        435                 440                 445             


His Glu Phe Tyr Asp Val Ala Asn Pro Val Gly Asn Pro Gly Ser Val 
    450                 455                 460                 


Leu Thr Gln Tyr Trp Ser Leu Leu Asn Val Phe Glu Gln Phe Gln Phe 
465                 470                 475                 480 


Met Asn Lys Lys Thr Gln Pro His Pro Leu Glu Trp Asn Ser Phe Thr 
                485                 490                 495     


Glu Asp Lys Asn Ile Glu Lys Pro Gln Val Pro Phe Asp Ala Ile Glu 
            500                 505                 510         


Asn Lys Lys Ala Ala Val Pro Gln Ile Lys Asn Glu Asn Lys Glu Ile 
        515                 520                 525             


His Cys Ser Asp Asp Glu Asn Thr Pro Cys His Ile Lys Gln Ile Phe 
    530                 535                 540                 


Thr His Pro His Leu Glu Leu Asn Pro Asp Phe His Pro Lys Ile Lys 
545                 550                 555                 560 


Asp Tyr Tyr Cys Glu Val Pro Phe Asp Val Val Thr Val Thr Ile Gly 
                565                 570                 575     


Val Glu Thr Pro Lys Cys Leu Cys Lys Val His Leu Tyr Glu Gln Ala 
            580                 585                 590         


Gly Pro Ser Phe Ala Ser Tyr Pro Leu Gly Leu Gly Met Asn Lys Ile 
        595                 600                 605             


Ser Ile Phe Val Val Asp Glu Ser Pro Ala His Gly Glu Thr Leu Ile 
    610                 615                 620                 


Thr Tyr Lys Leu Thr Ile Tyr Arg Glu Asp Arg Pro Ser Leu Pro Leu 
625                 630                 635                 640 


Phe Glu Ala Phe Thr Ala Cys Gly Phe Val Gln Asp Cys Gly Leu Leu 
                645                 650                 655     


Ile His Pro Glu Glu Thr Cys Gly Leu Gln Pro Ile Ser Ser Asp Tyr 
            660                 665                 670         


Ile Gly Ala Ile Leu Gln Ser Glu Leu Lys Arg Cys Pro Ser Gly Asp 
        675                 680                 685             


Met Lys Gly Gln Trp Ile Val Pro Cys Leu Ser Cys Ser Asp Asn Arg 
    690                 695                 700                 


Thr Cys Asp Trp Arg Glu Ile Thr Trp Gln Pro His Asn Cys Gln Tyr 
705                 710                 715                 720 


Gly Val Leu Thr Lys Pro Gln Leu Gln Gln Cys Leu Gly Gly Arg Lys 
                725                 730                 735     


Ile Leu Phe Ile Gly Asp Ser Thr Asn Arg Gly Ile Met Tyr Tyr Leu 
            740                 745                 750         


Ile Glu Arg Leu Asn Glu Thr Leu Gln Glu Trp Gln Lys Val His Gly 
        755                 760                 765             


Thr Lys Phe Tyr His Asn Val Asn Gly Gly Lys Thr Leu Ile Ser Tyr 
    770                 775                 780                 


Ser Tyr Tyr Pro Gln Phe Trp Ile Ser Pro Ser Leu Arg Pro Thr Phe 
785                 790                 795                 800 


Glu Asn Ala Leu Glu His Leu Leu Gln Arg Ser Arg Pro Leu Glu Asn 
                805                 810                 815     


Thr Gly Gln Thr Val Leu Val Val Gly Gly Val Gln Trp Leu Asn Ser 
            820                 825                 830         


Asn His Leu Gln Ile Ile His Lys Val Leu Lys Arg Glu Asn Leu Leu 
        835                 840                 845             


Asn Ile Leu Val Ile Ile Lys Thr Leu Gly Ile Gly Phe His Leu Pro 
    850                 855                 860                 


Val Asp Gly Val His Phe Leu Thr Gln Ser Glu Val Gln Asn Leu Trp 
865                 870                 875                 880 


Lys Glu Asn Leu Ile Ile Leu Asp Thr Ala Lys Lys His Gly Tyr Glu 
                885                 890                 895     


Val Val Asp Thr Phe Thr Ile Thr Met Gly Arg Tyr Lys Glu Phe Leu 
            900                 905                 910         


Gln Gly Lys Cys Gly Cys His Phe His Glu Val Val Lys Ser Lys Leu 
        915                 920                 925             


Ser Lys Glu Tyr Asn Phe Ile Lys Met Lys Arg Ser Arg Asn His Ile 
    930                 935                 940                 


Met Gly Arg Tyr Phe Ser Asn Gln Ser Lys Leu Gln Gln Gly Thr Val 
945                 950                 955                 960 


Thr Asn Phe Arg Ser Pro Tyr His Val Arg Gly Pro Ile Asn Gln Val 
                965                 970                 975     


Cys Ser Glu Ile Leu Leu Ser Arg Met Cys Ala Asn Lys Arg Thr Met 
            980                 985                 990         


<210>  1774
<211>  216
<212>  PRT
<213>  Homo Sapiens

<400>  1774

Ser Val Gln Lys Glu Asp Pro Ala Pro Tyr Leu Val Tyr Leu Lys Ser 
1               5                   10                  15      


His Phe Asn Pro Cys Val Gly Val Leu Ile Lys Pro Ser Trp Val Leu 
            20                  25                  30          


Ala Pro Ala His Cys Tyr Leu Pro Asn Leu Lys Val Met Leu Gly Asn 
        35                  40                  45              


Phe Lys Ser Arg Val Arg Asp Gly Thr Glu Gln Thr Ile Asn Pro Ile 
    50                  55                  60                  


Gln Ile Val Arg Tyr Trp Asn Tyr Ser His Ser Ala Pro Gln Asp Asp 
65                  70                  75                  80  


Leu Met Leu Ile Lys Leu Ala Lys Pro Ala Met Leu Asn Pro Lys Val 
                85                  90                  95      


Gln Pro Leu Thr Leu Ala Thr Thr Asn Val Arg Pro Gly Thr Val Cys 
            100                 105                 110         


Leu Leu Ser Gly Leu Asp Trp Ser Gln Glu Asn Ser Gly Arg His Pro 
        115                 120                 125             


Asp Leu Arg Gln Asn Leu Glu Ala Pro Val Met Ser Asp Arg Glu Cys 
    130                 135                 140                 


Gln Lys Thr Glu Gln Gly Lys Ser His Arg Asn Ser Leu Cys Val Lys 
145                 150                 155                 160 


Phe Val Lys Val Phe Ser Arg Ile Phe Gly Glu Val Ala Val Ala Thr 
                165                 170                 175     


Val Ile Cys Lys Asp Lys Leu Gln Gly Ile Glu Val Gly His Phe Met 
            180                 185                 190         


Gly Gly Asp Val Gly Ile Tyr Thr Asn Val Tyr Lys Tyr Val Ser Trp 
        195                 200                 205             


Ile Glu Asn Thr Ala Lys Asp Lys 
    210                 215     


<210>  1775
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  1775

Val Thr Phe Thr Ile Asn Cys Ser Gly Phe Gly Gln His Gly Ala Asp 
1               5                   10                  15      


Pro Thr Thr Leu Asn Ser Val Phe Asn Arg Lys Pro Phe Arg Pro Val 
            20                  25                  30          


Thr Asn Ile Ser Val Pro Thr Gln Val Asn Ile Ser Phe Ala Met Ser 
        35                  40                  45              


Ala Ile Leu Asp Val Asn Glu Gln Leu His Leu Leu Ser Ser Phe Leu 
    50                  55                  60                  


Trp Leu Glu Met Val Trp Asp Asn Pro Phe Ile Ser Trp Asn Pro Glu 
65                  70                  75                  80  


Glu Cys Glu Gly Ile Thr Lys Met Ser Met Ala Ala Lys Asn Leu Trp 
                85                  90                  95      


Leu Pro Asp Ile Phe Ile Ile Glu Leu Met Asp Val Asp Lys Thr Pro 
            100                 105                 110         


Lys Gly Leu Thr Ala Tyr Val Ser Asn Glu Gly Arg Ile Arg Tyr Lys 
        115                 120                 125             


Lys Pro Met Lys Val Asp Ser Ile Cys Asn Leu Asp Ile Phe Tyr Phe 
    130                 135                 140                 


Pro Phe Asp Gln Gln Asn Cys Thr Leu Thr Phe Ser Ser Phe Leu Tyr 
145                 150                 155                 160 


Thr Val Asp Ser Met Leu Leu Asp Met Glu Lys Glu Val Trp Glu Ile 
                165                 170                 175     


Thr Asp Ala Ser Arg Asn Ile Leu Gln Thr His Gly Glu Trp Glu Leu 
            180                 185                 190         


Leu Gly Leu Ser Lys Ala Thr Ala Lys Leu Ser Arg Gly Gly Asn Leu 
        195                 200                 205             


Tyr Asp Gln Ile Val Phe Tyr Val Ala Ile Arg Arg Arg Pro Ser 
    210                 215                 220             


<210>  1776
<211>  293
<212>  PRT
<213>  Homo Sapiens

<400>  1776

Leu Leu Phe Ile Tyr Gln Glu Val Ser Arg Leu Trp Ser Lys Ser Ala 
1               5                   10                  15      


Val Gln Asn Lys Val Val Val Ile Thr Asp Ala Ile Ser Gly Leu Gly 
            20                  25                  30          


Lys Glu Cys Ala Arg Val Phe His Thr Gly Gly Ala Arg Leu Val Leu 
        35                  40                  45              


Cys Gly Lys Asn Trp Glu Arg Leu Glu Asn Leu Tyr Asp Ala Leu Ile 
    50                  55                  60                  


Ser Val Ala Asp Pro Ser Lys Thr Phe Thr Pro Lys Leu Val Leu Leu 
65                  70                  75                  80  


Asp Leu Ser Asp Ile Ser Cys Val Pro Asp Val Ala Lys Glu Val Leu 
                85                  90                  95      


Asp Cys Tyr Gly Cys Val Asp Ile Leu Ile Asn Asn Ala Ser Val Lys 
            100                 105                 110         


Val Lys Gly Pro Ala His Lys Ile Ser Leu Glu Leu Asp Lys Lys Ile 
        115                 120                 125             


Met Asp Ala Asn Tyr Phe Gly Pro Ile Thr Leu Thr Lys Ala Leu Leu 
    130                 135                 140                 


Pro Asn Met Ile Ser Arg Arg Thr Gly Gln Ile Val Leu Val Asn Asn 
145                 150                 155                 160 


Ile Gln Gly Lys Phe Gly Ile Pro Phe Arg Thr Thr Tyr Ala Ala Ser 
                165                 170                 175     


Lys His Ala Ala Leu Gly Phe Phe Asp Cys Leu Arg Ala Glu Val Glu 
            180                 185                 190         


Glu Tyr Asp Val Val Ile Ser Thr Val Ser Pro Thr Phe Ile Arg Ser 
        195                 200                 205             


Tyr His Val Tyr Pro Glu Gln Gly Asn Trp Glu Ala Ser Ile Trp Lys 
    210                 215                 220                 


Phe Phe Phe Arg Lys Leu Thr Tyr Gly Val His Pro Val Glu Val Ala 
225                 230                 235                 240 


Glu Glu Val Met Arg Thr Val Arg Arg Lys Lys Gln Glu Val Phe Met 
                245                 250                 255     


Ala Asn Pro Ile Pro Lys Ala Ala Val Tyr Val Arg Thr Phe Phe Pro 
            260                 265                 270         


Glu Phe Phe Phe Ala Val Val Ala Cys Gly Val Lys Glu Lys Leu Asn 
        275                 280                 285             


Val Pro Glu Glu Gly 
    290             


<210>  1777
<211>  893
<212>  PRT
<213>  Homo Sapiens

<400>  1777

Asn Ser Leu Ile Gln Leu Asn Asn Asn Gly Tyr Glu Gly Ile Val Val 
1               5                   10                  15      


Ala Ile Asp Pro Asn Val Pro Glu Asp Glu Thr Leu Ile Gln Gln Ile 
            20                  25                  30          


Lys Asp Met Val Thr Gln Ala Ser Leu Tyr Leu Phe Glu Ala Thr Gly 
        35                  40                  45              


Lys Arg Phe Tyr Phe Lys Asn Val Ala Ile Leu Ile Pro Glu Thr Trp 
    50                  55                  60                  


Lys Thr Lys Ala Asp Tyr Val Arg Pro Lys Leu Glu Thr Tyr Lys Asn 
65                  70                  75                  80  


Ala Asp Val Leu Val Ala Glu Ser Thr Pro Pro Gly Asn Asp Glu Pro 
                85                  90                  95      


Tyr Thr Glu Gln Met Gly Asn Cys Gly Glu Lys Gly Glu Arg Ile His 
            100                 105                 110         


Leu Thr Pro Asp Phe Ile Ala Gly Lys Lys Leu Ala Glu Tyr Gly Pro 
        115                 120                 125             


Gln Gly Arg Ala Phe Val His Glu Trp Ala His Leu Arg Trp Gly Val 
    130                 135                 140                 


Phe Asp Glu Tyr Asn Asn Asp Glu Lys Phe Tyr Leu Ser Asn Gly Arg 
145                 150                 155                 160 


Ile Gln Ala Val Arg Cys Ser Ala Gly Ile Thr Gly Thr Asn Val Val 
                165                 170                 175     


Lys Lys Cys Gln Gly Gly Ser Cys Tyr Thr Lys Arg Cys Thr Phe Asn 
            180                 185                 190         


Lys Val Thr Gly Leu Tyr Glu Lys Gly Cys Glu Phe Val Leu Gln Ser 
        195                 200                 205             


Arg Gln Thr Glu Lys Ala Ser Ile Met Phe Ala Gln His Val Asp Ser 
    210                 215                 220                 


Ile Val Glu Phe Cys Thr Glu Gln Asn His Asn Lys Glu Ala Pro Asn 
225                 230                 235                 240 


Lys Gln Asn Gln Lys Cys Asn Leu Arg Ser Thr Trp Glu Val Ile Arg 
                245                 250                 255     


Asp Ser Glu Asp Phe Lys Lys Thr Thr Pro Met Thr Thr Gln Pro Pro 
            260                 265                 270         


Asn Pro Thr Phe Ser Leu Leu Gln Ile Gly Gln Arg Ile Val Cys Leu 
        275                 280                 285             


Val Leu Asp Lys Ser Gly Ser Met Ala Thr Gly Asn Arg Leu Asn Arg 
    290                 295                 300                 


Leu Asn Gln Ala Gly Gln Leu Phe Leu Leu Gln Thr Val Glu Leu Gly 
305                 310                 315                 320 


Ser Trp Val Gly Met Val Thr Phe Asp Ser Ala Ala His Val Gln Asn 
                325                 330                 335     


Glu Leu Ile Gln Ile Asn Ser Gly Ser Asp Arg Asp Thr Leu Ala Lys 
            340                 345                 350         


Arg Leu Pro Ala Ala Ala Ser Gly Gly Thr Ser Ile Cys Ser Gly Leu 
        355                 360                 365             


Arg Ser Ala Phe Thr Val Ile Arg Lys Lys Tyr Pro Thr Asp Gly Ser 
    370                 375                 380                 


Glu Ile Val Leu Leu Thr Asp Gly Glu Asp Asn Thr Ile Ser Gly Cys 
385                 390                 395                 400 


Phe Asn Glu Val Lys Gln Ser Gly Ala Ile Ile His Thr Val Ala Leu 
                405                 410                 415     


Gly Pro Ser Ala Ala Gln Glu Leu Glu Glu Leu Ser Lys Met Thr Gly 
            420                 425                 430         


Gly Leu Gln Thr Tyr Ala Ser Asp Gln Val Gln Asn Asn Gly Leu Ile 
        435                 440                 445             


Asp Ala Phe Gly Ala Leu Ser Ser Gly Asn Gly Ala Val Ser Gln Arg 
    450                 455                 460                 


Ser Ile Gln Leu Glu Ser Lys Gly Leu Thr Leu Gln Asn Ser Gln Trp 
465                 470                 475                 480 


Met Asn Gly Thr Val Ile Val Asp Ser Thr Val Gly Lys Asp Thr Leu 
                485                 490                 495     


Phe Leu Ile Thr Trp Thr Met Gln Pro Pro Gln Ile Leu Leu Trp Asp 
            500                 505                 510         


Pro Ser Gly Gln Lys Gln Gly Gly Phe Val Val Asp Lys Asn Thr Lys 
        515                 520                 525             


Met Ala Tyr Leu Gln Ile Pro Gly Ile Ala Lys Val Gly Thr Trp Lys 
    530                 535                 540                 


Tyr Ser Leu Gln Ala Ser Ser Gln Thr Leu Thr Leu Thr Val Thr Ser 
545                 550                 555                 560 


Arg Ala Ser Asn Ala Thr Leu Pro Pro Ile Thr Val Thr Ser Lys Thr 
                565                 570                 575     


Asn Lys Asp Thr Ser Lys Phe Pro Ser Pro Leu Val Val Tyr Ala Asn 
            580                 585                 590         


Ile Arg Gln Gly Ala Ser Pro Ile Leu Arg Ala Ser Val Thr Ala Leu 
        595                 600                 605             


Ile Glu Ser Val Asn Gly Lys Thr Val Thr Leu Glu Leu Leu Asp Asn 
    610                 615                 620                 


Gly Ala Gly Ala Asp Ala Thr Lys Asp Asp Gly Val Tyr Ser Arg Tyr 
625                 630                 635                 640 


Phe Thr Thr Tyr Asp Thr Asn Gly Arg Tyr Ser Val Lys Val Arg Ala 
                645                 650                 655     


Leu Gly Gly Val Asn Ala Ala Arg Arg Arg Val Ile Pro Gln Gln Ser 
            660                 665                 670         


Gly Ala Leu Tyr Ile Pro Gly Trp Ile Glu Asn Asp Glu Ile Gln Trp 
        675                 680                 685             


Asn Pro Pro Arg Pro Glu Ile Asn Lys Asp Asp Val Gln His Lys Gln 
    690                 695                 700                 


Val Cys Phe Ser Arg Thr Ser Ser Gly Gly Ser Phe Val Ala Ser Asp 
705                 710                 715                 720 


Val Pro Asn Ala Pro Ile Pro Asp Leu Phe Pro Pro Gly Gln Ile Thr 
                725                 730                 735     


Asp Leu Lys Ala Glu Ile His Gly Gly Ser Leu Ile Asn Leu Thr Trp 
            740                 745                 750         


Thr Ala Pro Gly Asp Asp Tyr Asp His Gly Thr Ala His Lys Tyr Ile 
        755                 760                 765             


Ile Arg Ile Ser Thr Ser Ile Leu Asp Leu Arg Asp Lys Phe Asn Glu 
    770                 775                 780                 


Ser Leu Gln Val Asn Thr Thr Ala Leu Ile Pro Lys Glu Ala Asn Ser 
785                 790                 795                 800 


Glu Glu Val Phe Leu Phe Lys Pro Glu Asn Ile Thr Phe Glu Asn Gly 
                805                 810                 815     


Thr Asp Leu Phe Ile Ala Ile Gln Ala Val Asp Lys Val Asp Leu Lys 
            820                 825                 830         


Ser Glu Ile Ser Asn Ile Ala Arg Val Ser Leu Phe Ile Pro Pro Gln 
        835                 840                 845             


Thr Pro Pro Glu Thr Pro Ser Pro Asp Glu Thr Ser Ala Pro Cys Pro 
    850                 855                 860                 


Asn Ile His Ile Asn Ser Thr Ile Pro Gly Ile His Ile Leu Lys Ile 
865                 870                 875                 880 


Met Trp Lys Trp Ile Gly Glu Leu Gln Leu Ser Ile Ala 
                885                 890             


<210>  1778
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  1778

Ile Arg Leu Val Pro Pro Tyr Pro Ser Ser Gln Glu Asp Pro Ile His 
1               5                   10                  15      


Ile Ala Cys Met Ala Pro Gly Asn Phe Pro Gly Ala Asn Phe Thr Leu 
            20                  25                  30          


Tyr Arg Gly Gly Gln Val Val Gln Leu Leu Gln Ala Pro Thr Asp Gln 
        35                  40                  45              


Arg Gly Val Thr Phe Asn Leu Ser Gly Gly Ser Ser Lys Ala Pro Gly 
    50                  55                  60                  


Gly Pro Phe His Cys Gln Tyr Gly Val Leu Gly Glu Leu Asn Gln Ser 
65                  70                  75                  80  


Gln Leu Ser Asp Leu Ser Glu Pro Val Asn Val Ser Phe Pro Val Pro 
                85                  90                  95      


Thr Trp 
        


<210>  1779
<211>  314
<212>  PRT
<213>  Homo Sapiens

<400>  1779

Gln Asp Thr Cys Arg Gln Gly His Pro Gly Ile Pro Gly Asn Pro Gly 
1               5                   10                  15      


His Asn Gly Leu Pro Gly Arg Asp Gly Arg Asp Gly Ala Lys Gly Asp 
            20                  25                  30          


Lys Gly Asp Ala Gly Glu Pro Gly Cys Pro Gly Ser Pro Gly Lys Asp 
        35                  40                  45              


Gly Thr Ser Gly Glu Lys Gly Glu Arg Gly Ala Asp Gly Lys Val Glu 
    50                  55                  60                  


Ala Lys Gly Ile Lys Gly Asp Gln Gly Ser Arg Gly Ser Pro Gly Lys 
65                  70                  75                  80  


His Gly Pro Lys Gly Leu Ala Gly Pro Met Gly Glu Lys Gly Leu Arg 
                85                  90                  95      


Gly Glu Thr Gly Pro Gln Gly Gln Lys Gly Asn Lys Gly Asp Val Gly 
            100                 105                 110         


Pro Thr Gly Pro Glu Gly Pro Arg Gly Asn Ile Gly Pro Leu Gly Pro 
        115                 120                 125             


Thr Gly Leu Pro Gly Pro Met Gly Pro Ile Gly Lys Pro Gly Pro Lys 
    130                 135                 140                 


Gly Glu Ala Gly Pro Thr Gly Pro Gln Gly Glu Pro Gly Val Arg Gly 
145                 150                 155                 160 


Ile Arg Gly Trp Lys Gly Asp Arg Gly Glu Lys Gly Lys Ile Gly Glu 
                165                 170                 175     


Thr Leu Val Leu Pro Lys Ser Ala Phe Thr Val Gly Leu Thr Val Leu 
            180                 185                 190         


Ser Lys Phe Pro Ser Ser Asp Val Pro Ile Lys Phe Asp Lys Ile Leu 
        195                 200                 205             


Tyr Asn Glu Phe Asn His Tyr Asp Thr Ala Val Gly Lys Phe Thr Cys 
    210                 215                 220                 


His Ile Ala Gly Val Tyr Tyr Phe Thr Tyr His Ile Thr Val Phe Ser 
225                 230                 235                 240 


Arg Asn Val Gln Val Ser Leu Val Lys Asn Gly Val Lys Ile Leu His 
                245                 250                 255     


Thr Arg Asp Ala Tyr Val Ser Ser Glu Asp Gln Ala Ser Gly Ser Ile 
            260                 265                 270         


Val Leu Gln Leu Lys Leu Gly Asp Glu Met Trp Leu Gln Val Thr Gly 
        275                 280                 285             


Gly Glu Arg Phe Asn Gly Leu Phe Ala Asp Glu Asp Asp Asp Thr Thr 
    290                 295                 300                 


Phe Thr Gly Phe Leu Leu Phe Ser Ser Gln 
305                 310                 


<210>  1780
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  1780

Ala Ala Ile Ser His Glu Asp Tyr Pro Ala Asp Glu Gly Asp Gln Ile 
1               5                   10                  15      


Ser Ser Asn Asp Asn Leu Ile Phe Asp Asp Tyr Arg Gly Lys Gly Cys 
            20                  25                  30          


Val Asp Asp Ser Gly Phe Val Tyr Lys Leu Gly Glu Arg Phe Phe Pro 
        35                  40                  45              


Gly His Ser Asn Cys Pro Cys Val Cys Ala Leu Asp Gly Pro Val Cys 
    50                  55                  60                  


Asp Gln Pro Glu Cys Pro Lys Ile His Pro Lys Cys Thr Lys Val Glu 
65                  70                  75                  80  


His Asn Gly Cys Cys Pro Glu Cys Lys Glu Val Lys Asn Phe Cys Glu 
                85                  90                  95      


Tyr His Gly Lys Asn Tyr Lys Ile Leu Glu Glu Phe Lys Pro Ser Pro 
            100                 105                 110         


Cys Glu Trp Cys Arg Cys Glu Pro Ser Asn Glu Val His Cys Val Val 
        115                 120                 125             


Ala Asp Cys Ala Val Pro Glu Cys Val Asn Pro Val Tyr Glu Pro Glu 
    130                 135                 140                 


Gln Cys Cys Pro Val Cys Lys Asn Gly Pro Asn Cys Phe Ala Gly Thr 
145                 150                 155                 160 


Thr Ile Ile Pro Ala Gly Ile Glu Val Lys Val Asp Glu Cys Asn Ile 
                165                 170                 175     


Cys His Cys His Asn Gly Asp Trp Trp Lys Pro Ala Gln Cys Ser Lys 
            180                 185                 190         


Arg Glu Cys Gln Gly Lys Gln Thr Val 
        195                 200     


<210>  1781
<211>  135
<212>  PRT
<213>  Homo Sapiens

<400>  1781

Asp Leu Asp Thr Ala Ala Arg Arg Gly Gln His Gln Val Pro Gln His 
1               5                   10                  15      


Arg Gly His Val Cys Tyr Leu Gly Val Cys Arg Thr His Arg Leu Ala 
            20                  25                  30          


Glu Ile Ile Tyr Trp Ile Arg Cys Leu His Gln Gly Ala Leu Gly Glu 
        35                  40                  45              


Gly Gln Pro Arg Ala Pro Gly Pro Leu Gln Leu Trp Ala Pro Pro Val 
    50                  55                  60                  


Ala Arg Gly Gly Ser Pro Ala Arg Phe Pro Gly Phe Arg Pro Ala Ala 
65                  70                  75                  80  


Arg Gly Leu Ala Gln Cys Pro Ala Arg Trp Val Thr Ser Gly Thr Ala 
                85                  90                  95      


Arg Pro Leu Leu Gly Phe Ser Leu Pro Ile Cys Met Leu Glu Leu Leu 
            100                 105                 110         


Leu His Ile Ser Ser Pro Leu Thr Pro Ala Pro Glu Thr Val Phe Pro 
        115                 120                 125             


Ser Pro Ser Pro Gly Cys Asp 
    130                 135 


<210>  1782
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  1782

Cys Tyr Gly Asp Ser Gly Gln Pro Val Asp Trp Phe Val Val Tyr Lys 
1               5                   10                  15      


Leu Pro Ala Leu Arg Gly Ser Gly Glu Ala Ala Gln Arg Gly Leu Gln 
            20                  25                  30          


Tyr Lys Tyr Leu Asp Glu Ser Ser Gly Gly Trp Arg Asp Gly Arg Ala 
        35                  40                  45              


Leu Ile Asn Ser Pro Glu Gly Ala Val Gly Arg Ser Leu Gln Pro Leu 
    50                  55                  60                  


Tyr Arg Ser Asn Thr Ser Gln Leu Ala Phe Leu Leu Tyr Asn Asp Gln 
65                  70                  75                  80  


Pro Pro Gln Pro Ser Lys Ala Gln Asp Ser Ser Met Arg Gly His Thr 
                85                  90                  95      


Lys Gly Val Leu Leu Leu Asp His Asp Gly Gly Phe Trp Leu Val His 
            100                 105                 110         


Ser Val Pro Asn Phe Pro Pro Pro Ala Ser Ser Ala Ala Tyr Ser Trp 
        115                 120                 125             


Pro His Ser Ala Cys Thr Tyr Gly Gln Thr Leu Leu Cys Val Ser Phe 
    130                 135                 140                 


Pro Phe Ala Gln Phe Ser Lys Met Gly Lys Gln Leu Thr Tyr Thr Tyr 
145                 150                 155                 160 


Pro Trp Val Tyr Asn Tyr Gln Leu Glu Gly Ile Phe Ala Gln Glu Phe 
                165                 170                 175     


Pro Asp Leu Glu Asn Val Val Lys Gly His His Val Ser Gln Glu Pro 
            180                 185                 190         


Trp Asn Ser Ser Ile Thr Leu Thr Ser Gln Ala Gly Ala Val Phe Gln 
        195                 200                 205             


Ser Phe Ala Lys Phe Ser Lys Phe Gly Asp Asp Leu Tyr Ser Gly Trp 
    210                 215                 220                 


Leu Ala Ala Ala Leu Gly Thr Asn Leu Gln Val Gln Phe Trp His Lys 
225                 230                 235                 240 


Thr Val Gly Ile Leu Pro Ser Asn Cys Ser Asp Ile Trp Gln Val Leu 
                245                 250                 255     


Asn Val Asn Gln Ile Ala Phe Pro Gly Pro Ala Gly Pro Ser Phe Asn 
            260                 265                 270         


Ser Thr Glu Asp His Ser Lys Trp Cys Val Ser Pro Lys Gly Pro Trp 
        275                 280                 285             


Thr Cys Val Gly Asp Met Asn Arg Asn Gln Gly Glu Glu Gln Arg Gly 
    290                 295                 300                 


Gly Gly Thr Leu Cys Ala Gln Leu Pro Ala Leu Trp Lys Ala Phe Gln 
305                 310                 315                 320 


Pro Leu Val Lys Asn Tyr Gln Pro Cys Asn Gly Met Ala Arg Lys Pro 
                325                 330                 335     


Ser Arg Ala Tyr Lys Ile 
            340         


<210>  1783
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  1783

Leu Glu Ile Gly Arg Phe Asp Pro Glu Arg Gly Arg Gly Ala Ala Pro 
1               5                   10                  15      


Cys Gln Ala Val Glu Ile Pro Met Cys Arg Gly Ile Gly Tyr Asn Leu 
            20                  25                  30          


Thr Arg Met Pro Asn Leu Leu Gly His Thr Ser Gln Gly Glu Ala Ala 
        35                  40                  45              


Ala Glu Leu Ala Glu Phe Ala Pro Leu Val Gln Tyr Gly Cys His Ser 
    50                  55                  60                  


His Leu Arg Phe Phe Leu Cys Ser Leu Tyr Ala Pro Met Cys Thr Asp 
65                  70                  75                  80  


Gln Val Ser Thr Pro Ile Pro Ala Cys Arg Pro Met Cys Glu Gln Ala 
                85                  90                  95      


Arg Leu Arg Cys Ala Pro Ile Met Glu Gln Phe Asn Phe Gly Trp Pro 
            100                 105                 110         


Asp Ser Leu Asp Cys Ala Arg Leu Pro Thr Arg Asn Asp Pro His Ala 
        115                 120                 125             


Leu Cys Met Glu Ala Pro Glu Asn Ala Thr Ala Gly Pro Ala Glu Pro 
    130                 135                 140                 


His Lys Gly Leu Gly Met Leu Pro Val Ala Pro Arg Pro Ala Arg Pro 
145                 150                 155                 160 


Pro Gly Asp Leu Gly Pro Gly Ala Gly Gly Ser Gly Thr Cys Glu Asn 
                165                 170                 175     


Arg Glu Lys Phe Gln Tyr Val Glu Lys Ser Arg Ser Cys Ala Pro Arg 
            180                 185                 190         


Cys Gly Pro Gly Val Glu Val Phe Trp Ser Arg Arg Asp Lys Asp 
        195                 200                 205         


<210>  1784
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  1784

Ser Ser Val Glu Leu Pro Tyr Glu Asp Leu Leu Arg Gln Glu Leu Arg 
1               5                   10                  15      


Lys Leu Lys Arg Arg Phe Leu Glu Glu His Glu Cys Leu Ser Glu Gln 
            20                  25                  30          


Gln Leu Glu Gln Phe Leu Gly Arg Val Leu Glu Ala Ser Asn Tyr Gly 
        35                  40                  45              


Val Ser Val Leu Ser Asn Ala Ser Gly Asn Trp Asn Trp Asp 
    50                  55                  60          


<210>  1785
<211>  356
<212>  PRT
<213>  Homo Sapiens

<400>  1785

Met Ala Phe Ser Gly Cys Gln Ala Pro Tyr Leu Ser Pro Ala Val Pro 
1               5                   10                  15      


Phe Ser Gly Thr Ile Gln Gly Gly Leu Gln Asp Gly Phe Gln Ile Thr 
            20                  25                  30          


Val Asn Gly Ala Val Leu Ser Cys Ser Gly Thr Arg Phe Ala Val Asp 
        35                  40                  45              


Phe Gln Thr Gly Phe Ser Gly Asn Asp Ile Ala Phe His Phe Asn Pro 
    50                  55                  60                  


Arg Phe Glu Asp Gly Gly Tyr Val Val Cys Asn Thr Arg Gln Lys Gly 
65                  70                  75                  80  


Thr Trp Gly Pro Glu Glu Arg Lys Met His Met Pro Phe Gln Lys Gly 
                85                  90                  95      


Met Pro Phe Asp Leu Cys Phe Leu Val Gln Ser Ser Asp Phe Lys Val 
            100                 105                 110         


Met Val Asn Gly Ser Leu Phe Val Gln Tyr Phe His Arg Val Pro Phe 
        115                 120                 125             


His Arg Val Asp Thr Ile Ser Val Asn Gly Ser Val Gln Leu Ser Tyr 
    130                 135                 140                 


Ile Ser Phe Gln Asn Pro Arg Ala Val Pro Val Gln Pro Ala Phe Ser 
145                 150                 155                 160 


Thr Val Pro Phe Ser Gln Pro Val Cys Phe Pro Pro Arg Pro Arg Gly 
                165                 170                 175     


Arg Arg Gln Lys Pro Pro Ile Val Arg Pro Ala Asn Pro Ala Pro Ile 
            180                 185                 190         


Thr Gln Thr Val Ile His Thr Val Gln Ser Ala Ser Gly Gln Met Phe 
        195                 200                 205             


Ser Gln Thr Pro Ala Ile Pro Pro Met Met Tyr Pro His Pro Ala Tyr 
    210                 215                 220                 


Pro Met Pro Phe Ile Thr Thr Ile Pro Gly Gly Leu Tyr Pro Ser Lys 
225                 230                 235                 240 


Ser Ile Ile Leu Ser Gly Thr Val Leu Pro Ser Ala Gln Arg Phe His 
                245                 250                 255     


Ile Asn Leu Cys Ser Gly Ser His Ile Ala Phe His Met Asn Pro Arg 
            260                 265                 270         


Phe Asp Glu Asn Ala Val Val Arg Asn Thr Gln Ile Asn Asn Ser Trp 
        275                 280                 285             


Gly Ser Glu Glu Arg Ser Leu Pro Arg Lys Met Pro Phe Val Arg Gly 
    290                 295                 300                 


Gln Ser Phe Ser Val Trp Ile Leu Cys Glu Ala His Cys Leu Lys Val 
305                 310                 315                 320 


Ala Val Asp Gly Gln His Val Phe Glu Tyr Tyr His Arg Leu Arg Asn 
                325                 330                 335     


Leu Pro Thr Ile Asn Lys Leu Glu Val Gly Gly Asp Ile Gln Leu Thr 
            340                 345                 350         


His Val Gln Thr 
        355     


<210>  1786
<211>  50
<212>  PRT
<213>  Homo Sapiens

<400>  1786

Ser Ser Arg Arg Cys Val Arg Leu His Glu Ser Cys Leu Gly Gln Gln 
1               5                   10                  15      


Val Pro Cys Cys Asp Pro Cys Ala Thr Cys Tyr Cys Arg Phe Phe Asn 
            20                  25                  30          


Ala Phe Cys Tyr Cys Arg Lys Leu Gly Thr Ala Met Asn Pro Cys Ser 
        35                  40                  45              


Arg Thr 
    50  


<210>  1787
<211>  290
<212>  PRT
<213>  Homo Sapiens

<400>  1787

Arg Phe Ser Gln Ser Phe Arg Glu Val Ala Gly Arg Phe Leu Ala Ser 
1               5                   10                  15      


Glu Ala Ser Thr His Leu Leu Val Phe Gly Met Glu Gln Arg Leu Pro 
            20                  25                  30          


Pro Asn Ser Glu Leu Val Gln Ala Val Leu Arg Leu Phe Gln Glu Pro 
        35                  40                  45              


Val Pro Lys Ala Ala Leu His Arg His Gly Arg Leu Ser Pro Arg Ser 
    50                  55                  60                  


Ala Gln Ala Arg Val Thr Val Glu Trp Leu Arg Val Arg Asp Asp Gly 
65                  70                  75                  80  


Ser Asn Arg Thr Ser Leu Ile Asp Ser Arg Leu Val Ser Val His Glu 
                85                  90                  95      


Ser Gly Trp Lys Ala Phe Asp Val Thr Glu Ala Val Asn Phe Trp Gln 
            100                 105                 110         


Gln Leu Ser Arg Pro Arg Gln Pro Leu Leu Leu Gln Val Ser Val Gln 
        115                 120                 125             


Arg Glu His Leu Gly Pro Leu Ala Ser Gly Ala His Lys Leu Val Arg 
    130                 135                 140                 


Phe Ala Ser Gln Gly Ala Pro Ala Gly Leu Gly Glu Pro Gln Leu Glu 
145                 150                 155                 160 


Leu His Thr Leu Asp Leu Arg Asp Tyr Gly Ala Gln Gly Asp Cys Asp 
                165                 170                 175     


Pro Glu Ala Pro Met Thr Glu Gly Thr Arg Cys Cys Arg Gln Glu Met 
            180                 185                 190         


Tyr Ile Asp Leu Gln Gly Met Lys Trp Ala Lys Asn Trp Val Leu Glu 
        195                 200                 205             


Pro Pro Gly Phe Leu Ala Tyr Glu Cys Val Gly Thr Cys Gln Gln Pro 
    210                 215                 220                 


Pro Glu Ala Leu Ala Phe Asn Trp Pro Phe Leu Gly Pro Arg Gln Cys 
225                 230                 235                 240 


Ile Ala Ser Glu Thr Ala Ser Leu Pro Met Ile Val Ser Ile Lys Glu 
                245                 250                 255     


Gly Gly Arg Thr Arg Pro Gln Val Val Ser Leu Pro Asn Met Arg Val 
            260                 265                 270         


Gln Lys Cys Ser Cys Ala Ser Asp Gly Ala Leu Val Pro Arg Arg Leu 
        275                 280                 285             


Gln Pro 
    290 


<210>  1788
<211>  520
<212>  PRT
<213>  Homo Sapiens

<400>  1788

Met Ser Gln Asp Asn Asp Thr Leu Met Arg Asp Ile Leu Gly His Glu 
1               5                   10                  15      


Leu Ala Ala Met Arg Leu Gln Lys Leu Glu Gln Gln Arg Arg Leu Phe 
            20                  25                  30          


Glu Lys Lys Gln Arg Gln Lys Arg Gln Glu Leu Leu Met Val Gln Ala 
        35                  40                  45              


Asn Pro Asp Ala Ser Pro Trp Leu Trp Arg Ser Cys Leu Arg Glu Glu 
    50                  55                  60                  


Arg Leu Leu Gly Asp Arg Gly Leu Gly Asn Pro Phe Leu Arg Lys Lys 
65                  70                  75                  80  


Val Ser Glu Ala His Leu Pro Ser Gly Ile His Ser Ala Leu Gly Thr 
                85                  90                  95      


Val Ser Cys Gly Gly Asp Gly Arg Gly Glu Arg Gly Leu Pro Thr Pro 
            100                 105                 110         


Arg Thr Glu Ala Val Phe Arg Asn Leu Gly Leu Gln Ser Pro Phe Leu 
        115                 120                 125             


Ser Trp Leu Pro Asp Asn Ser Asp Ala Glu Leu Glu Glu Val Ser Val 
    130                 135                 140                 


Glu Asn Gly Ser Val Ser Pro Pro Pro Phe Lys Gln Ser Pro Arg Ile 
145                 150                 155                 160 


Arg Arg Lys Gly Trp Gln Ala His Gln Arg Pro Gly Thr Arg Ala Glu 
                165                 170                 175     


Gly Glu Ser Asp Ser Gln Asp Met Gly Asp Ala His Lys Ser Pro Asn 
            180                 185                 190         


Met Gly Pro Asn Pro Gly Met Asp Gly Asp Cys Val Tyr Glu Asn Leu 
        195                 200                 205             


Ala Phe Gln Lys Glu Glu Asp Leu Glu Lys Lys Arg Glu Ala Ser Glu 
    210                 215                 220                 


Ser Thr Gly Thr Asn Ser Ser Ala Ala His Asn Glu Glu Leu Ser Lys 
225                 230                 235                 240 


Ala Leu Lys Gly Glu Gly Gly Thr Asp Ser Asp His Met Arg His Glu 
                245                 250                 255     


Ala Ser Leu Ala Ile Arg Ser Pro Cys Pro Gly Leu Glu Glu Asp Met 
            260                 265                 270         


Glu Ala Tyr Val Leu Arg Pro Ala Leu Pro Gly Thr Met Met Gln Cys 
        275                 280                 285             


Tyr Leu Thr Arg Asp Lys His Gly Val Asp Lys Gly Leu Phe Pro Leu 
    290                 295                 300                 


Tyr Tyr Leu Tyr Leu Glu Thr Ser Asp Ser Leu Gln Arg Phe Leu Leu 
305                 310                 315                 320 


Ala Gly Arg Lys Arg Arg Arg Ser Lys Thr Ser Asn Tyr Leu Ile Ser 
                325                 330                 335     


Leu Asp Pro Thr His Leu Ser Arg Asp Gly Asp Asn Phe Val Gly Lys 
            340                 345                 350         


Val Arg Ser Asn Val Phe Ser Thr Lys Phe Thr Ile Phe Asp Asn Gly 
        355                 360                 365             


Val Asn Pro Asp Arg Glu His Leu Thr Arg Asn Thr Ala Arg Ile Arg 
    370                 375                 380                 


Gln Glu Leu Gly Ala Val Cys Tyr Glu Pro Asn Val Leu Gly Tyr Leu 
385                 390                 395                 400 


Gly Pro Arg Lys Met Thr Val Ile Leu Pro Gly Thr Asn Ser Gln Asn 
                405                 410                 415     


Gln Arg Ile Asn Val Gln Pro Leu Asn Glu Gln Glu Ser Leu Leu Ser 
            420                 425                 430         


Arg Tyr Gln Arg Gly Asp Lys Gln Gly Leu Leu Leu Leu His Asn Lys 
        435                 440                 445             


Thr Pro Ser Trp Asp Lys Glu Asn Gly Val Tyr Thr Leu Asn Phe His 
    450                 455                 460                 


Gly Arg Val Thr Arg Ala Ser Val Lys Asn Phe Gln Ile Val Asp Pro 
465                 470                 475                 480 


Lys His Gln Glu His Leu Val Leu Gln Phe Gly Arg Val Gly Pro Asp 
                485                 490                 495     


Thr Phe Thr Met Asp Phe Cys Phe Pro Phe Ser Pro Leu Gln Ala Phe 
            500                 505                 510         


Ser Ile Cys Leu Ser Ser Phe Asn 
        515                 520 


<210>  1789
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  1789

Met Ala Val Ser Arg Lys Asp Trp Ser Ala Leu Ser Ser Leu Ala Arg 
1               5                   10                  15      


Gln Arg Thr Leu Glu Asp Glu Glu Glu Gln Glu Arg Glu Arg Arg Arg 
            20                  25                  30          


Arg His Arg Asn Leu Ser Ser Thr Thr Asp Asp Glu Ala Pro Arg Leu 
        35                  40                  45              


Ser Gln Asn Gly Asp Arg Gln Ala Ser Ala Ser Glu Arg Leu Pro Ser 
    50                  55                  60                  


Val Glu Glu Ala Glu Val Pro Lys Pro Leu Pro Pro Ala Ser Lys Asp 
65                  70                  75                  80  


Glu Asp Glu Asp Ile Gln Ser Ile Leu Arg Thr Arg Gln Glu Arg Arg 
                85                  90                  95      


Gln Arg Arg Gln Val Val Glu Ala Ala Gln Ala Pro Ile Gln Glu Arg 
            100                 105                 110         


Leu Glu Ala Glu Glu Gly Arg Asn Ser Leu Ser Pro Val Gln Ala Thr 
        115                 120                 125             


Gln Lys Pro Leu Val Ser Lys Lys Glu Leu Glu Ile Pro Pro Arg Arg 
    130                 135                 140                 


Arg Leu Ser Arg Glu Gln Arg Gly Pro Trp Ala Leu Glu Glu Glu Ser 
145                 150                 155                 160 


Leu Val Gly Arg Glu Pro Glu Glu Arg Lys Lys Gly Val Pro Glu Lys 
                165                 170                 175     


Ser Pro Val Leu Glu Lys Ser Ser Met Pro Lys Lys Thr Ala Pro Glu 
            180                 185                 190         


Lys Ser Leu Val Ser Asp Lys Thr Ser Ile Ser Glu Lys Val Leu Ala 
        195                 200                 205             


Ser Glu Lys Thr Ser Leu Ser Glu Lys Ile Ala Val Ser Glu Lys Arg 
    210                 215                 220                 


Asn Ser Ser Glu Lys Lys Ser Val Leu Glu Lys Thr Ser Val Ser Glu 
225                 230                 235                 240 


Lys Ser Leu Ala Pro Gly Met Ala Leu Gly Ser Gly Arg Arg Leu Val 
                245                 250                 255     


Ser Glu Lys Ala Ser Ile Phe Glu Lys Ala Leu Ala Ser Glu Lys Ser 
            260                 265                 270         


Pro Thr Ala Asp Ala Lys Pro Ala Pro Lys Arg Ala Thr Ala Ser Glu 
        275                 280                 285             


Gln Pro Leu Ala Gln Glu Pro Pro Ala Ser Gly Gly Ser Pro Ala Thr 
    290                 295                 300                 


Thr Lys Glu Gln Arg Gly Arg Ala Leu Pro Gly Lys Asn Leu Pro Ser 
305                 310                 315                 320 


Leu Ala Lys Gln Gly Ala Ser Asp Pro Pro Thr Val Ala Ser Arg Leu 
                325                 330                 335     


Pro Pro Val Thr Leu Gln Val Lys Ile Pro Ser Lys Glu Glu Glu Ala 
            340                 345                 350         


Asp Met Ser Ser Pro Thr Gln Arg Thr Tyr Ser Ser Ser Leu Lys Arg 
        355                 360                 365             


Ser Ser Pro Arg Thr Ile Ser Phe Arg Met Lys Pro Lys Lys Glu Asn 
    370                 375                 380                 


Ser Glu Thr Thr Leu Thr Arg Ser Ala Ser Met Lys Leu Pro Asp Asn 
385                 390                 395                 400 


Thr Val Lys Leu Gly Glu Lys Leu Glu Arg Tyr His Thr Ala Ile Arg 
                405                 410                 415     


Arg Ser Glu Ser Val Lys Ser Arg Gly Leu Pro Cys Thr Glu Leu Phe 
            420                 425                 430         


Val Ala Pro Val Gly Val Ala Ser Lys Arg His Leu Phe Glu Lys Glu 
        435                 440                 445             


Leu Ala Gly Gln Ser Arg Ala Glu Pro Ala Ser Ser Arg Lys Glu Asn 
    450                 455                 460                 


Leu Arg Leu Ser Gly Val Val Thr Ser Arg Leu Asn Leu Trp Ile Ser 
465                 470                 475                 480 


Arg Thr Gln Glu Ser Gly Asp Gln Asp Pro Gln Glu Ala Gln Lys Ala 
                485                 490                 495     


Ser Ser Ala Thr Glu Arg Thr Gln Trp Gly Gln Lys Ser Asp Ser Ser 
            500                 505                 510         


Leu Asp Ala Glu Val 
        515         


<210>  1790
<211>  297
<212>  PRT
<213>  Homo Sapiens

<400>  1790

Ser Leu Tyr Pro Ser Leu Glu Asp Leu Lys Val Asp Lys Val Ile Gln 
1               5                   10                  15      


Ala Gln Thr Ala Phe Ser Ala Asn Pro Ala Asn Pro Ala Ile Leu Ser 
            20                  25                  30          


Glu Ala Ser Ala Pro Ile Pro His Asp Gly Asn Leu Tyr Pro Arg Leu 
        35                  40                  45              


Tyr Pro Glu Leu Ser Gln Tyr Met Gly Leu Ser Leu Asn Glu Glu Glu 
    50                  55                  60                  


Ile Arg Ala Asn Val Ala Val Val Ser Gly Ala Pro Leu Gln Gly Gln 
65                  70                  75                  80  


Leu Val Ala Arg Pro Ser Ser Ile Asn Tyr Met Val Ala Pro Val Thr 
                85                  90                  95      


Gly Asn Asp Val Gly Ile Arg Arg Ala Glu Ile Lys Gln Gly Ile Arg 
            100                 105                 110         


Glu Val Ile Leu Cys Lys Asp Gln Asp Gly Lys Ile Gly Leu Arg Leu 
        115                 120                 125             


Lys Ser Ile Asp Asn Gly Ile Phe Val Gln Leu Val Gln Ala Asn Ser 
    130                 135                 140                 


Pro Ala Ser Leu Val Gly Leu Arg Phe Gly Asp Gln Val Leu Gln Ile 
145                 150                 155                 160 


Asn Gly Glu Asn Cys Ala Gly Trp Ser Ser Asp Lys Ala His Lys Val 
                165                 170                 175     


Leu Lys Gln Ala Phe Gly Glu Lys Ile Thr Met Thr Ile Arg Asp Arg 
            180                 185                 190         


Pro Phe Glu Arg Thr Ile Thr Met His Lys Asp Ser Thr Gly His Val 
        195                 200                 205             


Gly Phe Ile Phe Lys Asn Gly Lys Ile Thr Ser Ile Val Lys Asp Ser 
    210                 215                 220                 


Ser Ala Ala Arg Asn Gly Leu Leu Thr Glu His Asn Ile Cys Glu Ile 
225                 230                 235                 240 


Asn Gly Gln Asn Val Ile Gly Leu Lys Asp Ser Gln Ile Ala Asp Ile 
                245                 250                 255     


Leu Ser Thr Ser Gly Thr Val Val Thr Ile Thr Ile Met Pro Ala Phe 
            260                 265                 270         


Ile Phe Glu His Ile Ile Lys Arg Met Ala Pro Ser Ile Met Lys Ser 
        275                 280                 285             


Leu Met Asp His Thr Ile Pro Glu Val 
    290                 295         


<210>  1791
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  1791

Asp Lys Arg Leu Arg Asp Asn His Glu Trp Lys Lys Leu Ile Met Val 
1               5                   10                  15      


Gln His Trp Pro Glu Thr Val Cys Glu Lys Ile Gln Asn Asp Cys Arg 
            20                  25                  30          


Asp Pro Pro Asp Tyr Trp Thr Ile His Gly Leu Trp Pro Asp Lys Ser 
        35                  40                  45              


Glu Gly Cys Asn Arg Ser Trp Pro Phe Asn Leu Glu Glu Ile Lys Asp 
    50                  55                  60                  


Leu Leu Pro Glu Met Arg Ala Tyr Trp Pro Asp Val Ile His Ser Phe 
65                  70                  75                  80  


Pro Asn Arg Ser Arg Phe Trp Lys His Glu Trp Glu Lys His Gly Thr 
                85                  90                  95      


Cys Ala Ala Gln Val Asp Ala Leu Asn Ser Gln Lys Lys Tyr Phe Gly 
            100                 105                 110         


Arg Ser Leu Glu Leu Tyr Arg Glu Leu Asp Leu Asn Ser Val Leu Leu 
        115                 120                 125             


Lys Leu Gly Ile Lys Pro Ser Ile Asn Tyr Tyr Gln Val Ala Asp Phe 
    130                 135                 140                 


Lys Asp Ala Leu Ala Arg Val Tyr Gly Val Ile Pro Lys Ile Gln Cys 
145                 150                 155                 160 


Leu Pro Pro Ser Gln Asp Glu Glu Val Gln Thr Ile Gly Gln Ile Glu 
                165                 170                 175     


Leu Cys Leu Thr Lys Gln Asp Gln Gln Leu Gln Asn Cys Thr Glu Pro 
            180                 185                 190         


Gly Glu Gln Pro Ser Pro Lys Gln Glu Val Trp Leu Ala Asn Gly Ala 
        195                 200                 205             


Ala Glu Ser Arg Gly Leu Arg Val Cys Glu Asp Gly Pro Val Phe Tyr 
    210                 215                 220                 


Pro Pro Pro Lys Lys Thr Lys His 
225                 230         


<210>  1792
<211>  50
<212>  PRT
<213>  Homo Sapiens

<400>  1792

Met Ala Ala Thr Ala Ser Pro Gln Pro Leu Ala Thr Glu Asp Ala Asp 
1               5                   10                  15      


Ser Glu Asn Ser Ser Phe Tyr Tyr Tyr Asp Tyr Leu Asp Glu Val Ala 
            20                  25                  30          


Phe Met Leu Cys Arg Lys Asp Ala Val Val Ser Phe Gly Lys Val Phe 
        35                  40                  45              


Leu Pro 
    50  


<210>  1793
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  1793

Glu Arg Met Cys Ile Gln Gly Ser Gln Phe Asn Val Glu Val Gly Arg 
1               5                   10                  15      


Ser Asp Lys Leu Ser Leu Pro Gly Phe Glu Asn Leu Thr Ala Gly Tyr 
            20                  25                  30          


Asn Lys Phe Leu Arg Pro Asn Phe Gly Gly Glu Pro Val Gln Ile Ala 
        35                  40                  45              


Leu Thr Leu Asp Ile Ala Ser Ile Ser Ser Ile Ser Glu Ser Asn Met 
    50                  55                  60                  


Asp Tyr Thr Ala Thr Ile Tyr Leu Arg Gln Arg Trp Met Asp Gln Arg 
65                  70                  75                  80  


Leu Val Phe Glu Gly Asn Lys Ser Phe Thr Leu Asp Ala Arg Leu Val 
                85                  90                  95      


Glu Phe Leu Trp Val Pro Asp Thr Tyr Ile Val Glu Ser Lys Lys Ser 
            100                 105                 110         


Phe Leu His Glu Val Thr Val Gly Asn Arg Leu Ile Arg Leu Phe Ser 
        115                 120                 125             


Asn Gly Thr Val Leu Tyr Ala Leu Arg Ile Thr Thr Thr Val Ala Cys 
    130                 135                 140                 


Asn Met Asp Leu Ser Lys Tyr Pro Met Asp Thr Gln Thr Cys Lys Leu 
145                 150                 155                 160 


Gln Leu Glu Ser Trp Gly Tyr Asp Gly Asn Asp Val Glu Phe Thr Trp 
                165                 170                 175     


Leu Arg Gly Asn Asp Ser Val Arg Gly Leu Glu His Leu Arg Leu Ala 
            180                 185                 190         


Gln Tyr Thr Ile Glu Arg Tyr Phe Thr Leu Val Thr Arg Ser Gln Gln 
        195                 200                 205             


Glu Thr Gly Asn Tyr Thr Arg Leu Val Leu Gln Phe Glu Leu Arg Arg 
    210                 215                 220                 


Asn Val 
225     


<210>  1794
<211>  407
<212>  PRT
<213>  Homo Sapiens

<400>  1794

Ser Pro Ser Pro Ser Pro Ser Pro Ser Gln Asn Ala Thr Gln Thr Thr 
1               5                   10                  15      


Thr Asp Ser Ser Asn Lys Thr Ala Pro Thr Pro Ala Ser Ser Val Thr 
            20                  25                  30          


Ile Met Ala Thr Asp Thr Ala Gln Gln Ser Thr Val Pro Thr Ser Lys 
        35                  40                  45              


Ala Asn Glu Ile Leu Ala Ser Val Lys Ala Thr Thr Leu Gly Val Ser 
    50                  55                  60                  


Ser Asp Ser Pro Gly Thr Thr Thr Leu Ala Gln Gln Val Ser Gly Pro 
65                  70                  75                  80  


Val Asn Thr Thr Val Ala Arg Gly Gly Gly Ser Gly Asn Pro Thr Thr 
                85                  90                  95      


Thr Ile Glu Ser Pro Lys Ser Thr Lys Ser Ala Asp Thr Thr Thr Val 
            100                 105                 110         


Ala Thr Ser Thr Ala Thr Ala Lys Pro Asn Thr Thr Ser Ser Gln Asn 
        115                 120                 125             


Gly Ala Glu Asp Thr Thr Asn Ser Gly Gly Lys Ser Ser His Ser Val 
    130                 135                 140                 


Thr Thr Asp Leu Thr Ser Thr Lys Ala Glu His Leu Thr Thr Pro His 
145                 150                 155                 160 


Pro Thr Ser Pro Leu Ser Pro Arg Gln Pro Thr Ser Thr His Pro Val 
                165                 170                 175     


Ala Thr Pro Thr Ser Ser Gly His Asp His Leu Met Lys Ile Ser Ser 
            180                 185                 190         


Ser Ser Ser Thr Val Ala Ile Pro Gly Tyr Thr Phe Thr Ser Pro Gly 
        195                 200                 205             


Met Thr Thr Thr Leu Pro Ser Ser Val Ile Ser Gln Arg Thr Gln Gln 
    210                 215                 220                 


Thr Ser Ser Gln Met Pro Ala Ser Ser Thr Ala Pro Ser Ser Gln Glu 
225                 230                 235                 240 


Thr Val Gln Pro Thr Ser Pro Ala Thr Ala Leu Arg Thr Pro Thr Leu 
                245                 250                 255     


Pro Glu Thr Met Ser Ser Ser Pro Thr Ala Ala Ser Thr Thr His Arg 
            260                 265                 270         


Tyr Pro Lys Thr Pro Ser Pro Thr Val Ala His Glu Ser Asn Trp Ala 
        275                 280                 285             


Lys Cys Glu Asp Leu Glu Thr Gln Thr Gln Ser Glu Lys Gln Leu Val 
    290                 295                 300                 


Leu Asn Leu Thr Gly Asn Thr Leu Cys Ala Gly Gly Ala Ser Asp Glu 
305                 310                 315                 320 


Lys Leu Ile Ser Leu Ile Cys Arg Ala Val Lys Ala Thr Phe Asn Pro 
                325                 330                 335     


Ala Gln Asp Lys Cys Gly Ile Arg Leu Ala Ser Val Pro Gly Ser Gln 
            340                 345                 350         


Thr Val Val Val Lys Glu Ile Thr Ile His Thr Lys Leu Pro Ala Lys 
        355                 360                 365             


Asp Val Tyr Glu Arg Leu Lys Asp Lys Trp Asp Glu Leu Lys Glu Ala 
    370                 375                 380                 


Gly Val Ser Asp Met Lys Leu Gly Asp Gln Gly Pro Pro Glu Glu Ala 
385                 390                 395                 400 


Glu Asp Arg Phe Ser Met Pro 
                405         


<210>  1795
<211>  297
<212>  PRT
<213>  Homo Sapiens

<400>  1795

Ala Asp Thr Cys Pro Glu Val Lys Val Val Gly Leu Glu Gly Ser Asp 
1               5                   10                  15      


Lys Leu Thr Ile Leu Arg Gly Cys Pro Gly Leu Pro Gly Ala Pro Gly 
            20                  25                  30          


Pro Lys Gly Glu Ala Gly Val Ile Gly Glu Arg Gly Glu Arg Gly Leu 
        35                  40                  45              


Pro Gly Ala Pro Gly Lys Ala Gly Pro Val Gly Pro Lys Gly Asp Arg 
    50                  55                  60                  


Gly Glu Lys Gly Met Arg Gly Glu Lys Gly Asp Ala Gly Gln Ser Gln 
65                  70                  75                  80  


Ser Cys Ala Thr Gly Pro Arg Asn Cys Lys Asp Leu Leu Asp Arg Gly 
                85                  90                  95      


Tyr Phe Leu Ser Gly Trp His Thr Ile Tyr Leu Pro Asp Cys Arg Pro 
            100                 105                 110         


Leu Thr Val Leu Cys Asp Met Asp Thr Asp Gly Gly Gly Trp Thr Val 
        115                 120                 125             


Phe Gln Arg Arg Met Asp Gly Ser Val Asp Phe Tyr Arg Asp Trp Ala 
    130                 135                 140                 


Ala Tyr Lys Gln Gly Phe Gly Ser Gln Leu Gly Glu Phe Trp Leu Gly 
145                 150                 155                 160 


Asn Asp Asn Ile His Ala Leu Thr Ala Gln Gly Ser Ser Glu Leu Arg 
                165                 170                 175     


Val Asp Leu Val Asp Phe Glu Gly Asn His Gln Phe Ala Lys Tyr Lys 
            180                 185                 190         


Ser Phe Lys Val Ala Asp Glu Ala Glu Lys Tyr Lys Leu Val Leu Gly 
        195                 200                 205             


Ala Phe Val Gly Gly Ser Ala Gly Asn Ser Leu Thr Gly His Asn Asn 
    210                 215                 220                 


Asn Phe Phe Ser Thr Lys Asp Gln Asp Asn Asp Val Ser Ser Ser Asn 
225                 230                 235                 240 


Cys Ala Glu Lys Phe Gln Gly Ala Trp Trp Tyr Ala Asp Cys His Ala 
                245                 250                 255     


Ser Asn Leu Asn Gly Leu Tyr Leu Met Gly Pro His Glu Ser Tyr Ala 
            260                 265                 270         


Asn Gly Ile Asn Trp Ser Ala Ala Lys Gly Tyr Lys Tyr Ser Tyr Lys 
        275                 280                 285             


Val Ser Glu Met Lys Val Arg Pro Ala 
    290                 295         


<210>  1796
<211>  357
<212>  PRT
<213>  Homo Sapiens

<400>  1796

Thr Cys Pro Ala Ala Cys His Cys Pro Leu Glu Ala Pro Lys Cys Ala 
1               5                   10                  15      


Pro Gly Val Gly Leu Val Arg Asp Gly Cys Gly Cys Cys Lys Val Cys 
            20                  25                  30          


Ala Lys Gln Leu Asn Glu Asp Cys Ser Lys Thr Gln Pro Cys Asp His 
        35                  40                  45              


Thr Lys Gly Leu Glu Cys Asn Phe Gly Ala Ser Ser Thr Ala Leu Lys 
    50                  55                  60                  


Gly Ile Cys Arg Ala Gln Ser Glu Gly Arg Pro Cys Glu Tyr Asn Ser 
65                  70                  75                  80  


Arg Ile Tyr Gln Asn Gly Glu Ser Phe Gln Pro Asn Cys Lys His Gln 
                85                  90                  95      


Cys Thr Cys Ile Asp Gly Ala Val Gly Cys Ile Pro Leu Cys Pro Gln 
            100                 105                 110         


Glu Leu Ser Leu Pro Asn Leu Gly Cys Pro Asn Pro Arg Leu Val Lys 
        115                 120                 125             


Val Thr Gly Gln Cys Cys Glu Glu Trp Val Cys Asp Glu Asp Ser Ile 
    130                 135                 140                 


Lys Asp Pro Met Glu Asp Gln Asp Gly Leu Leu Gly Lys Glu Leu Gly 
145                 150                 155                 160 


Phe Asp Ala Ser Glu Val Glu Leu Thr Arg Asn Asn Glu Leu Ile Ala 
                165                 170                 175     


Val Gly Lys Gly Ser Ser Leu Lys Arg Leu Pro Val Phe Gly Met Glu 
            180                 185                 190         


Pro Arg Ile Leu Tyr Asn Pro Leu Gln Gly Gln Lys Cys Ile Val Gln 
        195                 200                 205             


Thr Thr Ser Trp Ser Gln Cys Ser Lys Thr Cys Gly Thr Gly Ile Ser 
    210                 215                 220                 


Thr Arg Val Thr Asn Asp Asn Pro Glu Cys Arg Leu Val Lys Glu Thr 
225                 230                 235                 240 


Arg Ile Cys Glu Val Arg Pro Cys Gly Gln Pro Val Tyr Ser Ser Leu 
                245                 250                 255     


Lys Lys Gly Lys Lys Cys Ser Lys Thr Lys Lys Ser Pro Glu Pro Val 
            260                 265                 270         


Arg Phe Thr Tyr Ala Gly Cys Leu Ser Val Lys Lys Tyr Arg Pro Lys 
        275                 280                 285             


Tyr Cys Gly Ser Cys Val Asp Gly Arg Cys Cys Thr Pro Gln Leu Thr 
    290                 295                 300                 


Arg Thr Val Lys Met Arg Phe Arg Cys Glu Asp Gly Glu Thr Phe Ser 
305                 310                 315                 320 


Lys Asn Val Met Met Ile Gln Ser Cys Lys Cys Asn Tyr Asn Cys Pro 
                325                 330                 335     


His Ala Asn Glu Ala Ala Phe Pro Phe Tyr Arg Leu Phe Asn Asp Ile 
            340                 345                 350         


His Lys Phe Arg Asp 
        355         


<210>  1797
<211>  361
<212>  PRT
<213>  Homo Sapiens

<400>  1797

Asn Glu Ile Leu Gly Leu Lys Leu Pro Gly Glu Pro Pro Leu Thr Ala 
1               5                   10                  15      


Asn Thr Val Cys Leu Thr Leu Ser Gly Leu Ser Lys Arg Gln Leu Gly 
            20                  25                  30          


Leu Cys Leu Arg Asn Pro Asp Val Thr Ala Ser Ala Leu Gln Gly Leu 
        35                  40                  45              


His Ile Ala Val His Glu Cys Gln His Gln Leu Arg Asp Gln Arg Trp 
    50                  55                  60                  


Asn Cys Ser Ala Leu Glu Gly Gly Gly Arg Leu Pro His His Ser Ala 
65                  70                  75                  80  


Ile Leu Lys Arg Gly Phe Arg Glu Ser Ala Phe Ser Phe Ser Met Leu 
                85                  90                  95      


Ala Ala Gly Val Met His Ala Val Ala Thr Ala Cys Ser Leu Gly Lys 
            100                 105                 110         


Leu Val Ser Cys Gly Cys Gly Trp Lys Gly Ser Gly Glu Gln Asp Arg 
        115                 120                 125             


Leu Arg Ala Lys Leu Leu Gln Leu Gln Ala Leu Ser Arg Gly Lys Ser 
    130                 135                 140                 


Phe Pro His Ser Leu Pro Ser Pro Gly Pro Gly Ser Ser Pro Ser Pro 
145                 150                 155                 160 


Gly Pro Gln Asp Thr Trp Glu Trp Gly Gly Cys Asn His Asp Met Asp 
                165                 170                 175     


Phe Gly Glu Lys Phe Ser Arg Asp Phe Leu Asp Ser Arg Glu Ala Pro 
            180                 185                 190         


Arg Asp Ile Gln Ala Arg Met Arg Ile His Asn Asn Arg Val Gly Arg 
        195                 200                 205             


Gln Val Val Thr Glu Asn Leu Lys Arg Lys Cys Lys Cys His Gly Thr 
    210                 215                 220                 


Ser Gly Ser Cys Gln Phe Lys Thr Cys Trp Arg Ala Ala Pro Glu Phe 
225                 230                 235                 240 


Arg Ala Val Gly Ala Ala Leu Arg Glu Arg Leu Gly Arg Ala Ile Phe 
                245                 250                 255     


Ile Asp Thr His Asn Arg Asn Ser Gly Ala Phe Gln Pro Arg Leu Arg 
            260                 265                 270         


Pro Arg Arg Leu Ser Gly Glu Leu Val Tyr Phe Glu Lys Ser Pro Asp 
        275                 280                 285             


Phe Cys Glu Arg Asp Pro Thr Met Gly Ser Pro Gly Thr Arg Gly Arg 
    290                 295                 300                 


Ala Cys Asn Lys Thr Ser Arg Leu Leu Asp Gly Cys Gly Ser Leu Cys 
305                 310                 315                 320 


Cys Gly Arg Gly His Asn Val Leu Arg Gln Thr Arg Val Glu Arg Cys 
                325                 330                 335     


His Cys Arg Phe His Trp Cys Cys Tyr Val Leu Cys Asp Glu Cys Lys 
            340                 345                 350         


Val Thr Glu Trp Val Asn Val Cys Lys 
        355                 360     


<210>  1798
<211>  533
<212>  PRT
<213>  Homo Sapiens

<400>  1798

Gln Asp Ser Ala Ser Pro Ile Arg Thr Thr His Thr Gly Gln Val Leu 
1               5                   10                  15      


Gly Ser Leu Val His Val Lys Gly Ala Asn Ala Gly Val Gln Thr Phe 
            20                  25                  30          


Leu Gly Ile Pro Phe Ala Lys Pro Pro Leu Gly Pro Leu Arg Phe Ala 
        35                  40                  45              


Pro Pro Glu Pro Pro Glu Ser Trp Ser Gly Val Arg Asp Gly Thr Thr 
    50                  55                  60                  


His Pro Ala Met Cys Leu Gln Asp Leu Thr Ala Val Glu Ser Glu Phe 
65                  70                  75                  80  


Leu Ser Gln Phe Asn Met Thr Phe Pro Ser Asp Ser Met Ser Glu Asp 
                85                  90                  95      


Cys Leu Tyr Leu Ser Ile Tyr Thr Pro Ala His Ser His Glu Gly Ser 
            100                 105                 110         


Asn Leu Pro Val Met Val Trp Ile His Gly Gly Ala Leu Val Phe Gly 
        115                 120                 125             


Met Ala Ser Leu Tyr Asp Gly Ser Met Leu Ala Ala Leu Glu Asn Val 
    130                 135                 140                 


Val Val Val Ile Ile Gln Tyr Arg Leu Gly Val Leu Gly Phe Phe Ser 
145                 150                 155                 160 


Thr Gly Asp Lys His Ala Thr Gly Asn Trp Gly Tyr Leu Asp Gln Val 
                165                 170                 175     


Ala Ala Leu Arg Trp Val Gln Gln Asn Ile Ala His Phe Gly Gly Asn 
            180                 185                 190         


Pro Asp Arg Val Thr Ile Phe Gly Glu Ser Ala Gly Gly Thr Ser Val 
        195                 200                 205             


Ser Ser Leu Val Val Ser Pro Ile Ser Gln Gly Leu Phe His Gly Ala 
    210                 215                 220                 


Ile Met Glu Ser Gly Val Ala Leu Leu Pro Gly Leu Ile Ala Ser Ser 
225                 230                 235                 240 


Ala Asp Val Ile Ser Thr Val Val Ala Asn Leu Ser Ala Cys Asp Gln 
                245                 250                 255     


Val Asp Ser Glu Ala Leu Val Gly Cys Leu Arg Gly Lys Ser Lys Glu 
            260                 265                 270         


Glu Ile Leu Ala Ile Asn Lys Pro Phe Lys Met Ile Pro Gly Val Val 
        275                 280                 285             


Asp Gly Val Phe Leu Pro Arg His Pro Gln Glu Leu Leu Ala Ser Ala 
    290                 295                 300                 


Asp Phe Lys Pro Val Pro Ser Ile Val Gly Val Asn Asn Asn Glu Phe 
305                 310                 315                 320 


Gly Trp Leu Ile Pro Lys Val Met Arg Ile Tyr Asp Thr Gln Lys Glu 
                325                 330                 335     


Met Asp Arg Glu Ala Ser Gln Ala Ala Leu Gln Lys Met Leu Thr Leu 
            340                 345                 350         


Leu Met Leu Pro Pro Thr Phe Gly Asp Leu Leu Arg Glu Glu Tyr Ile 
        355                 360                 365             


Gly Asp Asn Gly Asp Pro Gln Thr Leu Gln Ala Gln Phe Gln Glu Met 
    370                 375                 380                 


Met Ala Asp Ser Met Phe Val Ile Pro Ala Leu Gln Val Ala His Phe 
385                 390                 395                 400 


Gln Cys Ser Arg Ala Pro Val Tyr Phe Tyr Glu Phe Gln His Gln Pro 
                405                 410                 415     


Ser Trp Leu Lys Asn Ile Arg Pro Pro His Met Lys Ala Asp His Gly 
            420                 425                 430         


Asp Glu Leu Pro Phe Val Phe Arg Ser Phe Phe Gly Gly Asn Tyr Ile 
        435                 440                 445             


Lys Phe Thr Glu Glu Glu Glu Gln Leu Ser Arg Lys Met Met Lys Tyr 
    450                 455                 460                 


Trp Ala Asn Phe Ala Arg Asn Gly Asn Pro Asn Gly Glu Gly Leu Pro 
465                 470                 475                 480 


His Trp Pro Leu Phe Asp Gln Glu Glu Gln Tyr Leu Gln Leu Asn Leu 
                485                 490                 495     


Gln Pro Ala Val Gly Arg Ala Leu Lys Ala His Arg Leu Gln Phe Trp 
            500                 505                 510         


Lys Lys Ala Leu Pro Gln Lys Ile Gln Glu Leu Glu Glu Pro Glu Glu 
        515                 520                 525             


Arg His Thr Glu Leu 
    530             


<210>  1799
<211>  962
<212>  PRT
<213>  Homo Sapiens

<400>  1799

Gly Gly Tyr Glu Thr Cys Pro Thr Val Gln Pro Asn Met Leu Asn Val 
1               5                   10                  15      


His Leu Leu Pro His Thr His Asp Asp Val Gly Trp Leu Lys Thr Val 
            20                  25                  30          


Asp Gln Tyr Phe Tyr Gly Ile Lys Asn Asp Ile Gln His Ala Gly Val 
        35                  40                  45              


Gln Tyr Ile Leu Asp Ser Val Ile Ser Ala Leu Leu Ala Asp Pro Thr 
    50                  55                  60                  


Arg Arg Phe Ile Tyr Val Glu Ile Ala Phe Phe Ser Arg Trp Trp His 
65                  70                  75                  80  


Gln Gln Thr Asn Ala Thr Gln Glu Val Val Arg Asp Leu Val Arg Gln 
                85                  90                  95      


Gly Arg Leu Glu Phe Ala Asn Gly Gly Trp Val Met Asn Asp Glu Ala 
            100                 105                 110         


Ala Thr His Tyr Gly Ala Ile Val Asp Gln Met Thr Leu Gly Leu Arg 
        115                 120                 125             


Phe Leu Glu Asp Thr Phe Gly Asn Asp Gly Arg Pro Arg Val Ala Trp 
    130                 135                 140                 


His Ile Asp Pro Phe Gly His Ser Arg Glu Gln Ala Ser Leu Phe Ala 
145                 150                 155                 160 


Gln Met Gly Phe Asp Gly Phe Phe Phe Gly Arg Leu Asp Tyr Gln Asp 
                165                 170                 175     


Lys Trp Val Arg Met Gln Lys Leu Glu Met Glu Gln Val Trp Arg Ala 
            180                 185                 190         


Ser Thr Ser Leu Lys Pro Pro Thr Ala Asp Leu Phe Thr Gly Val Leu 
        195                 200                 205             


Pro Asn Gly Tyr Asn Pro Pro Arg Asn Leu Cys Trp Asp Val Leu Cys 
    210                 215                 220                 


Val Asp Gln Pro Leu Val Glu Asp Pro Arg Ser Pro Glu Tyr Asn Ala 
225                 230                 235                 240 


Lys Glu Leu Val Asp Tyr Phe Leu Asn Val Ala Thr Ala Gln Gly Arg 
                245                 250                 255     


Tyr Tyr Arg Thr Asn His Thr Val Met Thr Met Gly Ser Asp Phe Gln 
            260                 265                 270         


Tyr Glu Asn Ala Asn Met Trp Phe Lys Asn Leu Asp Lys Leu Ile Arg 
        275                 280                 285             


Leu Val Asn Ala Gln Gln Ala Lys Gly Ser Ser Val His Val Leu Tyr 
    290                 295                 300                 


Ser Thr Pro Ala Cys Tyr Leu Trp Glu Leu Asn Lys Ala Asn Leu Thr 
305                 310                 315                 320 


Trp Ser Val Lys His Asp Asp Phe Phe Pro Tyr Ala Asp Gly Pro His 
                325                 330                 335     


Gln Phe Trp Thr Gly Tyr Phe Ser Ser Arg Pro Ala Leu Lys Arg Tyr 
            340                 345                 350         


Glu Arg Leu Ser Tyr Asn Phe Leu Gln Val Cys Asn Gln Leu Glu Ala 
        355                 360                 365             


Leu Val Gly Leu Ala Ala Asn Val Gly Pro Tyr Gly Ser Gly Asp Ser 
    370                 375                 380                 


Ala Pro Leu Asn Glu Ala Met Ala Val Leu Gln His His Asp Ala Val 
385                 390                 395                 400 


Ser Gly Thr Ser Arg Gln His Val Ala Asn Asp Tyr Ala Arg Gln Leu 
                405                 410                 415     


Ala Ala Gly Trp Gly Pro Cys Glu Val Leu Leu Ser Asn Ala Leu Ala 
            420                 425                 430         


Arg Leu Arg Gly Phe Lys Asp His Phe Thr Phe Cys Gln Gln Leu Asn 
        435                 440                 445             


Ile Ser Ile Cys Pro Leu Ser Gln Thr Ala Ala Arg Phe Gln Val Ile 
    450                 455                 460                 


Val Tyr Asn Pro Leu Gly Arg Lys Val Asn Trp Met Val Arg Leu Pro 
465                 470                 475                 480 


Val Ser Glu Gly Val Phe Val Val Lys Asp Pro Asn Gly Arg Thr Val 
                485                 490                 495     


Pro Ser Asp Val Val Ile Phe Pro Ser Ser Asp Ser Gln Ala His Pro 
            500                 505                 510         


Pro Glu Leu Leu Phe Ser Ala Ser Leu Pro Ala Leu Gly Phe Ser Thr 
        515                 520                 525             


Tyr Ser Val Ala Gln Val Pro Arg Trp Lys Pro Gln Ala Arg Ala Pro 
    530                 535                 540                 


Gln Pro Ile Pro Arg Arg Ser Trp Ser Pro Ala Leu Thr Ile Glu Asn 
545                 550                 555                 560 


Glu His Ile Arg Ala Thr Phe Asp Pro Asp Thr Gly Leu Leu Met Glu 
                565                 570                 575     


Ile Met Asn Met Asn Gln Gln Leu Leu Leu Pro Val Arg Gln Thr Phe 
            580                 585                 590         


Phe Trp Tyr Asn Ala Ser Ile Gly Asp Asn Glu Ser Asp Gln Ala Ser 
        595                 600                 605             


Gly Ala Tyr Ile Phe Arg Pro Asn Gln Gln Lys Pro Leu Pro Val Ser 
    610                 615                 620                 


Arg Trp Ala Gln Ile His Leu Val Lys Thr Pro Leu Val Gln Glu Val 
625                 630                 635                 640 


His Gln Asn Phe Ser Ala Trp Cys Ser Gln Val Val Arg Leu Tyr Pro 
                645                 650                 655     


Gly Gln Arg His Leu Glu Leu Glu Trp Ser Val Gly Pro Ile Pro Val 
            660                 665                 670         


Gly Asp Thr Trp Gly Lys Glu Val Ile Ser Arg Phe Asp Thr Pro Leu 
        675                 680                 685             


Glu Thr Lys Gly Arg Phe Tyr Thr Asp Ser Asn Gly Arg Glu Ile Leu 
    690                 695                 700                 


Glu Arg Arg Arg Asp Tyr Arg Pro Thr Trp Lys Leu Asn Gln Thr Glu 
705                 710                 715                 720 


Pro Val Ala Gly Asn Tyr Tyr Pro Val Asn Thr Arg Ile Tyr Ile Thr 
                725                 730                 735     


Asp Gly Asn Met Gln Leu Thr Val Leu Thr Asp Arg Ser Gln Gly Gly 
            740                 745                 750         


Ser Ser Leu Arg Asp Gly Ser Leu Glu Leu Met Val His Arg Arg Leu 
        755                 760                 765             


Leu Lys Asp Asp Gly Arg Gly Val Ser Glu Pro Leu Met Glu Asn Gly 
    770                 775                 780                 


Ser Gly Ala Trp Val Arg Gly Arg His Leu Val Leu Leu Asp Thr Ala 
785                 790                 795                 800 


Gln Ala Ala Ala Ala Gly His Arg Leu Leu Ala Glu Gln Glu Val Leu 
                805                 810                 815     


Ala Pro Gln Val Val Leu Ala Pro Gly Gly Gly Ala Ala Tyr Asn Leu 
            820                 825                 830         


Gly Ala Pro Pro Arg Thr Gln Phe Ser Gly Leu Arg Arg Asp Leu Pro 
        835                 840                 845             


Pro Ser Val His Leu Leu Thr Leu Ala Ser Trp Gly Pro Glu Met Val 
    850                 855                 860                 


Leu Leu Arg Leu Glu His Gln Phe Ala Val Gly Glu Asp Ser Gly Arg 
865                 870                 875                 880 


Asn Leu Ser Ala Pro Val Thr Leu Asn Leu Arg Asp Leu Phe Ser Thr 
                885                 890                 895     


Phe Thr Ile Thr Arg Leu Gln Glu Thr Thr Leu Val Ala Asn Gln Leu 
            900                 905                 910         


Arg Glu Ala Ala Ser Arg Leu Lys Trp Thr Thr Asn Thr Gly Pro Thr 
        915                 920                 925             


Pro His Gln Thr Pro Tyr Gln Leu Asp Pro Ala Asn Ile Thr Leu Glu 
    930                 935                 940                 


Pro Met Glu Ile Arg Thr Phe Leu Ala Ser Val Gln Trp Lys Glu Val 
945                 950                 955                 960 


Asp Gly 
        


<210>  1800
<211>  318
<212>  PRT
<213>  Homo Sapiens

<400>  1800

Leu Gly Ala Ser Ile Ile Cys Asn Lys Ile Pro Gly Leu Ala Pro Arg 
1               5                   10                  15      


Gln Arg Ala Ile Cys Gln Ser Arg Pro Asp Ala Ile Ile Val Ile Gly 
            20                  25                  30          


Glu Gly Ser Gln Met Gly Leu Asp Glu Cys Gln Phe Gln Phe Arg Asn 
        35                  40                  45              


Gly Arg Trp Asn Cys Ser Ala Leu Gly Glu Arg Thr Val Phe Gly Lys 
    50                  55                  60                  


Glu Leu Lys Val Gly Ser Arg Glu Ala Ala Phe Thr Tyr Ala Ile Ile 
65                  70                  75                  80  


Ala Ala Gly Val Ala His Ala Ile Thr Ala Ala Cys Thr Gln Gly Asn 
                85                  90                  95      


Leu Ser Asp Cys Gly Cys Asp Lys Glu Lys Gln Gly Gln Tyr His Arg 
            100                 105                 110         


Asp Glu Gly Trp Lys Trp Gly Gly Cys Ser Ala Asp Ile Arg Tyr Gly 
        115                 120                 125             


Ile Gly Phe Ala Lys Val Phe Val Asp Ala Arg Glu Ile Lys Gln Asn 
    130                 135                 140                 


Ala Arg Thr Leu Met Asn Leu His Asn Asn Glu Ala Gly Arg Lys Ile 
145                 150                 155                 160 


Leu Glu Glu Asn Met Lys Leu Glu Cys Lys Cys His Gly Val Ser Gly 
                165                 170                 175     


Ser Cys Thr Thr Lys Thr Cys Trp Thr Thr Leu Pro Gln Phe Arg Glu 
            180                 185                 190         


Leu Gly Tyr Val Leu Lys Asp Lys Tyr Asn Glu Ala Val His Val Glu 
        195                 200                 205             


Pro Val Arg Ala Ser Arg Asn Lys Arg Pro Thr Phe Leu Lys Ile Lys 
    210                 215                 220                 


Lys Pro Leu Ser Tyr Arg Lys Pro Met Asp Thr Asp Leu Val Tyr Ile 
225                 230                 235                 240 


Glu Lys Ser Pro Asn Tyr Cys Glu Glu Asp Pro Val Thr Gly Ser Val 
                245                 250                 255     


Gly Thr Gln Gly Arg Ala Cys Asn Lys Thr Ala Pro Gln Ala Ser Gly 
            260                 265                 270         


Cys Asp Leu Met Cys Cys Gly Arg Gly Tyr Asn Thr His Gln Tyr Ala 
        275                 280                 285             


Arg Val Trp Gln Cys Asn Cys Lys Phe His Trp Cys Cys Tyr Val Lys 
    290                 295                 300                 


Cys Asn Thr Cys Ser Glu Arg Thr Glu Met Tyr Thr Cys Lys 
305                 310                 315             


<210>  1801
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1801

Met Trp Arg Val Thr Ala Phe Ile Gly Ser Asn Ile Val Thr Ser Gln 
1               5                   10                  15      


Thr Ile Trp Glu Gly Leu Trp Met Asn Cys Val Val Gln Ser Thr Gly 
            20                  25                  30          


Gln Met Gln Cys Lys Val Tyr Asp Ser Leu Leu Ala Leu Pro Gln Asp 
        35                  40                  45              


Leu Gln Ala Ala Arg 
    50              


<210>  1802
<211>  845
<212>  PRT
<213>  Homo Sapiens

<400>  1802

Leu Leu Val Ile Met Ser Leu Gly Leu Gly Leu Gly Leu Gly Leu Arg 
1               5                   10                  15      


Lys Leu Glu Lys Gln Gly Ser Cys Arg Lys Lys Cys Phe Asp Ala Ser 
            20                  25                  30          


Phe Arg Gly Leu Glu Asn Cys Arg Cys Asp Val Ala Cys Lys Asp Arg 
        35                  40                  45              


Gly Asp Cys Cys Trp Asp Phe Glu Asp Thr Cys Val Glu Ser Thr Arg 
    50                  55                  60                  


Ile Trp Met Cys Asn Lys Phe Arg Cys Gly Glu Thr Arg Leu Glu Ala 
65                  70                  75                  80  


Ser Leu Cys Ser Cys Ser Asp Asp Cys Leu Gln Arg Lys Asp Cys Cys 
                85                  90                  95      


Ala Asp Tyr Lys Ser Val Cys Gln Gly Glu Thr Ser Trp Leu Glu Glu 
            100                 105                 110         


Asn Cys Asp Thr Ala Gln Gln Ser Gln Cys Pro Glu Gly Phe Asp Leu 
        115                 120                 125             


Pro Pro Val Ile Leu Phe Ser Met Asp Gly Phe Arg Ala Glu Tyr Leu 
    130                 135                 140                 


Tyr Thr Trp Asp Thr Leu Met Pro Asn Ile Asn Lys Leu Lys Thr Cys 
145                 150                 155                 160 


Gly Ile His Ser Lys Tyr Met Arg Ala Met Tyr Pro Thr Lys Thr Phe 
                165                 170                 175     


Pro Asn His Tyr Thr Ile Val Thr Gly Leu Tyr Pro Glu Ser His Gly 
            180                 185                 190         


Ile Ile Asp Asn Asn Met Tyr Asp Val Asn Leu Asn Lys Asn Phe Ser 
        195                 200                 205             


Leu Ser Ser Lys Glu Gln Asn Asn Pro Ala Trp Trp His Gly Gln Pro 
    210                 215                 220                 


Met Trp Leu Thr Ala Met Tyr Gln Gly Leu Lys Ala Ala Thr Tyr Phe 
225                 230                 235                 240 


Trp Pro Gly Ser Glu Val Ala Ile Asn Gly Ser Phe Pro Ser Ile Tyr 
                245                 250                 255     


Met Pro Tyr Asn Gly Ser Val Pro Phe Glu Glu Arg Ile Ser Thr Leu 
            260                 265                 270         


Leu Lys Trp Leu Asp Leu Pro Lys Ala Glu Arg Pro Arg Phe Tyr Thr 
        275                 280                 285             


Met Tyr Phe Glu Glu Pro Asp Ser Ser Gly His Ala Gly Gly Pro Val 
    290                 295                 300                 


Ser Ala Arg Val Ile Lys Ala Leu Gln Val Val Asp His Ala Phe Gly 
305                 310                 315                 320 


Met Leu Met Glu Gly Leu Lys Gln Arg Asn Leu His Asn Cys Val Asn 
                325                 330                 335     


Ile Ile Leu Leu Ala Asp His Gly Met Asp Gln Thr Tyr Cys Asn Lys 
            340                 345                 350         


Met Glu Tyr Met Thr Asp Tyr Phe Pro Arg Ile Asn Phe Phe Tyr Met 
        355                 360                 365             


Tyr Glu Gly Pro Ala Pro Arg Ile Arg Ala His Asn Ile Pro His Asp 
    370                 375                 380                 


Phe Phe Ser Phe Asn Ser Glu Glu Ile Val Arg Asn Leu Ser Cys Arg 
385                 390                 395                 400 


Lys Pro Asp Gln His Phe Lys Pro Tyr Leu Thr Pro Asp Leu Pro Lys 
                405                 410                 415     


Arg Leu His Tyr Ala Lys Asn Val Arg Ile Asp Lys Val His Leu Phe 
            420                 425                 430         


Val Asp Gln Gln Trp Leu Ala Val Arg Ser Lys Ser Asn Thr Asn Cys 
        435                 440                 445             


Gly Gly Gly Asn His Gly Tyr Asn Asn Glu Phe Arg Ser Met Glu Ala 
    450                 455                 460                 


Ile Phe Leu Ala His Gly Pro Ser Phe Lys Glu Lys Thr Glu Val Glu 
465                 470                 475                 480 


Pro Phe Glu Asn Ile Glu Val Tyr Asn Leu Met Cys Asp Leu Leu Arg 
                485                 490                 495     


Ile Gln Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu Asn His Leu 
            500                 505                 510         


Leu Lys Val Pro Phe Tyr Glu Pro Ser His Ala Glu Glu Val Ser Lys 
        515                 520                 525             


Phe Ser Val Cys Gly Phe Ala Asn Pro Leu Pro Thr Glu Ser Leu Asp 
    530                 535                 540                 


Cys Phe Cys Pro His Leu Gln Asn Ser Thr Gln Leu Glu Gln Val Asn 
545                 550                 555                 560 


Gln Met Leu Asn Leu Thr Gln Glu Glu Ile Thr Ala Thr Val Lys Val 
                565                 570                 575     


Asn Leu Pro Phe Gly Arg Pro Arg Val Leu Gln Lys Asn Val Asp His 
            580                 585                 590         


Cys Leu Leu Tyr His Arg Glu Tyr Val Ser Gly Phe Gly Lys Ala Met 
        595                 600                 605             


Arg Met Pro Met Trp Ser Ser Tyr Thr Val Pro Gln Leu Gly Asp Thr 
    610                 615                 620                 


Ser Pro Leu Pro Pro Thr Val Pro Asp Cys Leu Arg Ala Asp Val Arg 
625                 630                 635                 640 


Val Pro Pro Ser Glu Ser Gln Lys Cys Ser Phe Tyr Leu Ala Asp Lys 
                645                 650                 655     


Asn Ile Thr His Gly Phe Leu Tyr Pro Pro Ala Ser Asn Arg Thr Ser 
            660                 665                 670         


Asp Ser Gln Tyr Asp Ala Leu Ile Thr Ser Asn Leu Val Pro Met Tyr 
        675                 680                 685             


Glu Glu Phe Arg Lys Met Trp Asp Tyr Phe His Ser Val Leu Leu Ile 
    690                 695                 700                 


Lys His Ala Thr Glu Arg Asn Gly Val Asn Val Val Ser Gly Pro Ile 
705                 710                 715                 720 


Phe Asp Tyr Asn Tyr Asp Gly His Phe Asp Ala Pro Asp Glu Ile Thr 
                725                 730                 735     


Lys His Leu Ala Asn Thr Asp Val Pro Ile Pro Thr His Tyr Phe Val 
            740                 745                 750         


Val Leu Thr Ser Cys Lys Asn Lys Ser His Thr Pro Glu Asn Cys Pro 
        755                 760                 765             


Gly Trp Leu Asp Val Leu Pro Phe Ile Ile Pro His Arg Pro Thr Asn 
    770                 775                 780                 


Val Glu Ser Cys Pro Glu Gly Lys Pro Glu Ala Leu Trp Val Glu Glu 
785                 790                 795                 800 


Arg Phe Thr Ala His Ile Ala Arg Val Arg Asp Val Glu Leu Leu Thr 
                805                 810                 815     


Gly Leu Asp Phe Tyr Gln Asp Lys Val Gln Pro Val Ser Glu Ile Leu 
            820                 825                 830         


Gln Leu Lys Thr Tyr Leu Pro Thr Phe Glu Thr Thr Ile 
        835                 840                 845 


<210>  1803
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  1803

Val Glu Pro Ile Ser Leu Gly Leu Ala Leu Ala Gly Val Leu Thr Gly 
1               5                   10                  15      


Tyr Ile Tyr Pro Arg Leu Tyr Cys Leu Phe Ala Glu Cys Cys Gly Gln 
            20                  25                  30          


Lys Arg Ser Leu Ser Arg Glu Ala Leu Gln Lys Asp Leu Asp Asp Asn 
        35                  40                  45              


Leu Phe Gly Gln His Leu Ala Lys Lys Ile Ile Leu Asn Ala Val Phe 
    50                  55                  60                  


Gly Phe Ile Asn Asn Pro Lys Pro Lys Lys Pro Leu Thr Leu Ser Leu 
65                  70                  75                  80  


His Gly Trp Thr Gly Thr Gly Lys Asn Phe Val Ser Lys Ile Ile Ala 
                85                  90                  95      


Glu Asn Ile Tyr Glu Gly Gly Leu Asn Ser Asp Tyr Val His Leu Phe 
            100                 105                 110         


Val Ala Thr Leu His Phe Pro His Ala Ser Asn Ile Thr Leu Tyr Lys 
        115                 120                 125             


Asp Gln Leu Gln Leu Trp Ile Arg Gly Asn Val Ser Ala Cys Ala Arg 
    130                 135                 140                 


Ser Ile Phe Ile Phe Asp Glu Met Asp Lys Met His Ala Gly Leu Ile 
145                 150                 155                 160 


Asp Ala Ile Lys Pro Phe Leu Asp Tyr Tyr Asp Leu Val Asp Gly Val 
                165                 170                 175     


Ser Tyr Gln Lys Ala Met Phe Ile Phe Leu Ser Asn Ala Gly Ala Glu 
            180                 185                 190         


Arg Ile Thr Asp Val Ala Leu Asp Phe Trp Arg Ser Gly Lys Gln Arg 
        195                 200                 205             


Glu Asp Ile Lys Leu Lys Asp Ile Glu His Ala Leu Ser Val Ser Val 
    210                 215                 220                 


Phe Asn Asn Lys Asn Ser Gly Phe Trp His Ser Ser Leu Ile His Arg 
225                 230                 235                 240 


Asn Leu Ile Asp Tyr Phe Val Pro Phe Leu Pro Leu Glu Tyr Lys His 
                245                 250                 255     


Leu Lys Met Cys Ile Arg Val Glu Met Gln Ser Arg Gly Tyr Glu Ile 
            260                 265                 270         


Asp Glu Asp Ile Val Ser Arg Val Ala Glu Glu Met Thr Phe Phe Pro 
        275                 280                 285             


Lys Glu Glu Arg Val Phe Ser Asp Lys Gly Cys Lys Thr Val Phe Thr 
    290                 295                 300                 


Lys Leu Asp Tyr Tyr Tyr Asp Asp 
305                 310         


<210>  1804
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  1804

Phe Glu Pro Ile Thr Val Gly Leu Ala Ile Gly Ala Ala Ser Ala Ile 
1               5                   10                  15      


Thr Gly Tyr Leu Ser Tyr Asn Asp Ile Tyr Cys Arg Phe Ala Glu Cys 
            20                  25                  30          


Cys Arg Glu Glu Arg Pro Leu Asn Ala Ser Ala Leu Lys Leu Asp Leu 
        35                  40                  45              


Glu Glu Lys Leu Phe Gly Gln His Leu Ala Thr Glu Val Ile Phe Lys 
    50                  55                  60                  


Ala Leu Thr Gly Phe Arg Asn Asn Lys Asn Pro Lys Lys Pro Leu Thr 
65                  70                  75                  80  


Leu Ser Leu His Gly Trp Ala Gly Thr Gly Lys Asn Phe Val Ser Gln 
                85                  90                  95      


Ile Val Ala Glu Asn Leu His Pro Lys Gly Leu Lys Ser Asn Phe Val 
            100                 105                 110         


His Leu Phe Val Ser Thr Leu His Phe Pro His Glu Gln Lys Ile Lys 
        115                 120                 125             


Leu Tyr Gln Asp Gln Leu Gln Lys Trp Ile Arg Gly Asn Val Ser Ala 
    130                 135                 140                 


Cys Ala Asn Ser Val Phe Ile Phe Asp Glu Met Asp Lys Leu His Pro 
145                 150                 155                 160 


Gly Ile Ile Asp Ala Ile Lys Pro Phe Leu Asp Tyr Tyr Glu Gln Val 
                165                 170                 175     


Asp Gly Val Ser Tyr Arg Lys Ala Ile Phe Ile Phe Leu Ser Asn Ala 
            180                 185                 190         


Gly Gly Asp Leu Ile Thr Lys Thr Ala Leu Asp Phe Trp Arg Ala Gly 
        195                 200                 205             


Arg Lys Arg Glu Asp Ile Gln Leu Lys Asp Leu Glu Pro Val Leu Ser 
    210                 215                 220                 


Val Gly Val Phe Asn Asn Lys His Ser Gly Leu Trp His Ser Gly Leu 
225                 230                 235                 240 


Ile Asp Lys Asn Leu Ile Asp Tyr Phe Ile Pro Phe Leu Pro Leu Glu 
                245                 250                 255     


Tyr Arg His Val Lys Met Cys Val Arg Ala Glu Met Arg Ala Arg Gly 
            260                 265                 270         


Ser Ala Ile Asp Glu Asp Ile Val Thr Arg Val Ala Glu Glu Met Thr 
        275                 280                 285             


Phe Phe Pro Arg Asp Glu Lys Ile Tyr Ser Asp Lys Gly Cys Lys Thr 
    290                 295                 300                 


Val Gln Ser Arg Leu Asp Phe His 
305                 310         


<210>  1805
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  1805

Ala Asn Gly Phe Phe Glu Glu Ile Arg Gln Gly Asn Ile Glu Arg Glu 
1               5                   10                  15      


Cys Lys Glu Glu Phe Cys Thr Phe Glu Glu Ala Arg Glu Ala Phe Glu 
            20                  25                  30          


Asn Asn Glu Lys Thr Lys Glu Phe Trp Ser Thr Tyr Thr Lys Ala Gln 
        35                  40                  45              


Gln Gly Glu Ser Asn Arg Gly Ser Asp Trp Phe Gln Phe Tyr Leu 
    50                  55                  60              


<210>  1806
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  1806

Tyr Arg Glu Arg Gln Val Val Ser His Leu Gln Asp Lys Tyr Val Phe 
1               5                   10                  15      


Ile Thr Gly Cys Asp Ser Gly Phe Gly Asn Leu Leu Ala Arg Gln Leu 
            20                  25                  30          


Asp Ala Arg Gly Leu Arg Val Leu Ala Ala Cys Leu Thr Glu Lys Gly 
        35                  40                  45              


Ala Glu Gln Leu Arg Gly Gln Thr Ser Asp Arg Leu Glu Thr Val Thr 
    50                  55                  60                  


Leu Asp Val Thr Lys Met Glu Ser Ile Ala Ala Ala Thr Gln Trp Val 
65                  70                  75                  80  


Lys Glu His Val Gly Asp Arg Gly Leu Trp Gly Leu Val Asn Asn Ala 
                85                  90                  95      


Gly Ile Leu Thr Pro Ile Thr Leu Cys Glu Trp Leu Asn Thr Glu Asp 
            100                 105                 110         


Ser Met Asn Met Leu Lys Val Asn Leu Ile Gly Val Ile Gln Val Thr 
        115                 120                 125             


Leu Ser Met Leu Pro Leu Val Arg Arg Ala Arg Gly Arg Ile Val Asn 
    130                 135                 140                 


Val Ser Ser Ile Leu Gly Arg Val Ala Phe Phe Val Gly Gly Tyr Cys 
145                 150                 155                 160 


Val Ser Lys Tyr Gly Val Glu Ala Phe Ser Asp Ile Leu Arg Arg Glu 
                165                 170                 175     


Ile Gln His Phe Gly Val Lys Ile Ser Ile Val Glu Pro Gly Tyr Phe 
            180                 185                 190         


Arg Thr Gly Met Thr Asn Met Thr Gln Ser Leu Glu Arg Met Lys Gln 
        195                 200                 205             


Ser Trp Lys Glu Ala Pro Lys His Ile Lys Glu Thr Tyr Gly Gln Gln 
    210                 215                 220                 


Tyr Phe Asp Ala Leu Tyr Asn Ile Met Lys Glu Gly Leu Leu Asn Cys 
225                 230                 235                 240 


Ser Thr Asn Leu Asn Leu Val Thr Asp Cys Met Glu His Ala Leu Thr 
                245                 250                 255     


Ser Val His Pro Arg Thr Arg Tyr Ser Ala Gly Trp Asp Ala Lys Phe 
            260                 265                 270         


Phe Phe Ile Pro Leu Ser Tyr Leu Pro Thr Ser Leu Ala Asp Tyr Ile 
        275                 280                 285             


Leu Thr Arg Ser Trp Pro Lys Pro Ala Gln Ala Val 
    290                 295                 300 


<210>  1807
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  1807

Gln Gln Leu Arg Gly Thr Arg Ala Met Asn Asp Ile Gly Asp Tyr Val 
1               5                   10                  15      


Gly Ser Asn Leu Glu Ile Ser Trp Leu Pro Asn Leu Asp Gly Leu Ile 
            20                  25                  30          


Ala Gly Tyr Ala Arg Asn Phe Arg Pro Gly Ile Gly Gly Pro Pro Val 
        35                  40                  45              


Asn Val Ala Leu Ala Leu Glu Val Ala Ser Ile Asp His Ile Ser Glu 
    50                  55                  60                  


Ala Asn Met Glu Tyr Thr Met Thr Val Phe Leu His Gln Ser Trp Arg 
65                  70                  75                  80  


Asp Ser Arg Leu Ser Tyr Asn His Thr Asn Glu Thr Leu Gly Leu Asp 
                85                  90                  95      


Ser Arg Phe Val Asp Lys Leu Trp Leu Pro Asp Thr Phe Ile Val Asn 
            100                 105                 110         


Ala Lys Ser Ala Trp Phe His Asp Val Thr Val Glu Asn Lys Leu Ile 
        115                 120                 125             


Arg Leu Gln Pro Asp Gly Val Ile Leu Tyr Ser Ile Arg Ile Thr Ser 
    130                 135                 140                 


Thr Val Ala Cys Asp Met Asp Leu Ala Lys Tyr Pro Met Asp Glu Gln 
145                 150                 155                 160 


Glu Cys Met Leu Asp Leu Glu Ser Tyr Gly Tyr Ser Ser Glu Asp Ile 
                165                 170                 175     


Val Tyr Tyr Trp Ser Glu Ser Gln Glu His Ile His Gly Leu Asp Lys 
            180                 185                 190         


Leu Gln Leu Ala Gln Phe Thr Ile Thr Ser Tyr Arg Phe Thr Thr Glu 
        195                 200                 205             


Leu Met Asn Phe Lys Ser Ala Gly Gln Phe Pro Arg Leu Ser Leu His 
    210                 215                 220                 


Phe His Leu Arg Arg Asn Arg Gly 
225                 230         


<210>  1808
<211>  368
<212>  PRT
<213>  Homo Sapiens

<400>  1808

Leu His Leu Gly Val Thr Pro Ser Val Ile Arg Lys Arg Tyr Asn Leu 
1               5                   10                  15      


Thr Ser Gln Asp Val Gly Ser Gly Thr Ser Asn Asn Ser Gln Ala Cys 
            20                  25                  30          


Ala Gln Phe Leu Glu Gln Tyr Phe His Asp Ser Asp Leu Ala Gln Phe 
        35                  40                  45              


Met Arg Leu Phe Gly Gly Asn Phe Ala His Gln Ala Ser Val Ala Arg 
    50                  55                  60                  


Val Val Gly Gln Gln Gly Arg Gly Arg Ala Gly Ile Glu Ala Ser Leu 
65                  70                  75                  80  


Asp Val Gln Tyr Leu Met Ser Ala Gly Ala Asn Ile Ser Thr Trp Val 
                85                  90                  95      


Tyr Ser Ser Pro Gly Arg His Glu Gly Gln Glu Pro Phe Leu Gln Trp 
            100                 105                 110         


Leu Met Leu Leu Ser Asn Glu Ser Ala Leu Pro His Val His Thr Val 
        115                 120                 125             


Ser Tyr Gly Asp Asp Glu Asp Ser Leu Ser Ser Ala Tyr Ile Gln Arg 
    130                 135                 140                 


Val Asn Thr Glu Leu Met Lys Ala Ala Ala Arg Gly Leu Thr Leu Leu 
145                 150                 155                 160 


Phe Ala Ser Gly Asp Ser Gly Ala Gly Cys Trp Ser Val Ser Gly Arg 
                165                 170                 175     


His Glu Phe Arg Pro Thr Phe Pro Ala Ser Ser Pro Tyr Val Thr Thr 
            180                 185                 190         


Val Gly Gly Thr Ser Phe Gln Glu Pro Phe Leu Ile Thr Asn Glu Ile 
        195                 200                 205             


Val Asp Tyr Ile Ser Gly Gly Gly Phe Ser Asn Val Phe Pro Arg Pro 
    210                 215                 220                 


Ser Tyr Gln Glu Glu Ala Val Thr Lys Phe Leu Ser Ser Ser Pro His 
225                 230                 235                 240 


Leu Pro Pro Ser Ser Tyr Phe Asn Ala Ser Gly Arg Ala Tyr Pro Asp 
                245                 250                 255     


Val Ala Ala Leu Ser Asp Gly Tyr Trp Val Val Ser Asn Arg Val Pro 
            260                 265                 270         


Ile Pro Trp Val Ser Gly Thr Ser Ala Ser Thr Pro Val Phe Gly Gly 
        275                 280                 285             


Ile Leu Ser Leu Ile Asn Glu His Arg Ile Leu Ser Gly Arg Pro Pro 
    290                 295                 300                 


Leu Gly Phe Leu Asn Pro Arg Leu Tyr Gln Gln His Gly Ala Gly Leu 
305                 310                 315                 320 


Phe Asp Val Thr Arg Gly Cys His Glu Ser Cys Leu Asp Glu Glu Val 
                325                 330                 335     


Glu Gly Gln Gly Phe Cys Ser Gly Pro Gly Trp Asp Pro Val Thr Gly 
            340                 345                 350         


Trp Gly Thr Pro Asn Phe Pro Ala Leu Leu Lys Thr Leu Leu Asn Pro 
        355                 360                 365             


<210>  1809
<211>  371
<212>  PRT
<213>  Homo Sapiens

<400>  1809

Glu Glu Ala Gly Ala Arg Val Gln Gln Asn Val Pro Ser Gly Thr Asp 
1               5                   10                  15      


Thr Gly Asp Pro Gln Ser Lys Pro Leu Gly Asp Trp Ala Ala Gly Thr 
            20                  25                  30          


Met Asp Pro Glu Ser Ser Ile Phe Ile Glu Asp Ala Ile Lys Tyr Phe 
        35                  40                  45              


Lys Glu Lys Val Ser Thr Gln Asn Leu Leu Leu Leu Leu Thr Asp Asn 
    50                  55                  60                  


Glu Ala Trp Asn Gly Phe Val Ala Ala Ala Glu Leu Pro Arg Asn Glu 
65                  70                  75                  80  


Ala Asp Glu Leu Arg Lys Ala Leu Asp Asn Leu Ala Arg Gln Met Ile 
                85                  90                  95      


Met Lys Asp Lys Asn Trp His Asp Lys Gly Gln Gln Tyr Arg Asn Trp 
            100                 105                 110         


Phe Leu Lys Glu Phe Pro Arg Leu Lys Ser Glu Leu Glu Asp Asn Ile 
        115                 120                 125             


Arg Arg Leu Arg Ala Leu Ala Asp Gly Val Gln Lys Val His Lys Gly 
    130                 135                 140                 


Thr Thr Ile Ala Asn Val Val Ser Gly Ser Leu Ser Ile Ser Ser Gly 
145                 150                 155                 160 


Ile Leu Thr Leu Val Gly Met Gly Leu Ala Pro Phe Thr Glu Gly Gly 
                165                 170                 175     


Ser Leu Val Leu Leu Glu Pro Gly Met Glu Leu Gly Ile Thr Ala Ala 
            180                 185                 190         


Leu Thr Gly Ile Thr Ser Ser Thr Met Asp Tyr Gly Lys Lys Trp Trp 
        195                 200                 205             


Thr Gln Ala Gln Ala His Asp Leu Val Ile Lys Ser Leu Asp Lys Leu 
    210                 215                 220                 


Lys Glu Val Arg Glu Phe Leu Gly Glu Asn Ile Ser Asn Phe Leu Ser 
225                 230                 235                 240 


Leu Ala Gly Asn Thr Tyr Gln Leu Thr Arg Gly Ile Gly Lys Asp Ile 
                245                 250                 255     


Arg Ala Leu Arg Arg Ala Arg Ala Asn Leu Gln Ser Val Pro His Ala 
            260                 265                 270         


Ser Ala Ser Arg Pro Arg Val Thr Glu Pro Ile Ser Ala Glu Ser Gly 
        275                 280                 285             


Glu Gln Val Glu Arg Val Asn Glu Pro Ser Ile Leu Glu Met Ser Arg 
    290                 295                 300                 


Gly Val Lys Leu Thr Asp Val Ala Pro Val Ser Phe Phe Leu Val Leu 
305                 310                 315                 320 


Asp Val Val Tyr Leu Val Tyr Glu Ser Lys His Leu His Glu Gly Ala 
                325                 330                 335     


Lys Ser Glu Thr Ala Glu Glu Leu Lys Lys Val Ala Gln Glu Leu Glu 
            340                 345                 350         


Glu Lys Leu Asn Ile Leu Asn Asn Asn Tyr Lys Ile Leu Gln Ala Asp 
        355                 360                 365             


Gln Glu Leu 
    370     


<210>  1810
<211>  287
<212>  PRT
<213>  Homo Sapiens

<400>  1810

Arg Thr Ala Glu Leu Gly Gln Gln Glu Leu Leu Arg Lys Ala Gly Thr 
1               5                   10                  15      


Leu Gln Asp Asp Val Arg Asp Gly Val Ala Pro Asn Gly Ser Ala Gln 
            20                  25                  30          


Gln Leu Pro Gln Thr Ile Ile Ile Gly Val Arg Lys Gly Gly Thr Arg 
        35                  40                  45              


Ala Leu Leu Glu Met Leu Ser Leu His Pro Asp Val Ala Ala Ala Glu 
    50                  55                  60                  


Asn Glu Val His Phe Phe Asp Trp Glu Glu His Tyr Ser His Gly Leu 
65                  70                  75                  80  


Gly Trp Tyr Leu Ser Gln Met Pro Phe Ser Trp Pro His Gln Leu Thr 
                85                  90                  95      


Val Glu Lys Thr Pro Ala Tyr Phe Thr Ser Pro Lys Val Pro Glu Arg 
            100                 105                 110         


Val Tyr Ser Met Asn Pro Ser Ile Arg Leu Leu Leu Ile Leu Arg Asp 
        115                 120                 125             


Pro Ser Glu Arg Val Leu Ser Asp Tyr Thr Gln Val Phe Tyr Asn His 
    130                 135                 140                 


Met Gln Lys His Lys Pro Tyr Pro Ser Ile Glu Glu Phe Leu Val Arg 
145                 150                 155                 160 


Asp Gly Arg Leu Asn Val Asp Tyr Lys Ala Leu Asn Arg Ser Leu Tyr 
                165                 170                 175     


His Val His Met Gln Asn Trp Leu Arg Phe Phe Pro Leu Arg His Ile 
            180                 185                 190         


His Ile Val Asp Gly Asp Arg Leu Ile Arg Asp Pro Phe Pro Glu Ile 
        195                 200                 205             


Gln Lys Val Glu Arg Phe Leu Lys Leu Ser Pro Gln Ile Asn Ala Ser 
    210                 215                 220                 


Asn Phe Tyr Phe Asn Lys Thr Lys Gly Phe Tyr Cys Leu Arg Asp Ser 
225                 230                 235                 240 


Gly Arg Asp Arg Cys Leu His Glu Ser Lys Gly Arg Ala His Pro Gln 
                245                 250                 255     


Val Asp Pro Lys Leu Leu Asn Lys Leu His Glu Tyr Phe His Glu Pro 
            260                 265                 270         


Asn Lys Lys Phe Phe Glu Leu Val Gly Arg Thr Phe Asp Trp His 
        275                 280                 285         


<210>  1811
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  1811

Tyr Phe Gly Leu Thr Gly Ser Glu Pro Leu Thr Ile Leu Pro Leu Thr 
1               5                   10                  15      


Leu Glu Pro Glu Ala Ala Ala Gln Ala His Tyr Lys Ala Cys Asp Arg 
            20                  25                  30          


Leu Lys Leu Glu Arg Lys Gln Arg Arg Met Cys Arg Arg Asp Pro Gly 
        35                  40                  45              


Val Ala Glu Thr Leu Val Glu Ala Val Ser Met Ser Ala Leu Glu Cys 
    50                  55                  60                  


Gln Phe Gln Phe Arg Phe Glu Arg Trp Asn Cys Thr Leu Glu Gly Arg 
65                  70                  75                  80  


Tyr Arg Ala Ser Leu Leu Lys Arg Gly Phe Lys Glu Thr Ala Phe Leu 
                85                  90                  95      


Tyr Ala Ile Ser Ser Ala Gly Leu Thr His Ala Leu Ala Lys Ala Cys 
            100                 105                 110         


Ser Ala Gly Arg Met Glu Arg Cys Thr Cys Asp Glu Ala Pro Asp Leu 
        115                 120                 125             


Glu Asn Arg Glu Ala Trp Gln Trp Gly Gly Cys Gly Asp Asn Leu Lys 
    130                 135                 140                 


Tyr Ser Ser Lys Phe Val Lys Glu Phe Leu Gly Arg Arg Ser Ser Lys 
145                 150                 155                 160 


Asp Leu Arg Ala Arg Val Asp Phe His Asn Asn Leu Val Gly Val Lys 
                165                 170                 175     


Val Ile Lys Ala Gly Val Glu Thr Thr Cys Lys Cys His Gly Val Ser 
            180                 185                 190         


Gly Ser Cys Thr Val Arg Thr Cys Trp Arg Gln Leu Ala Pro Phe His 
        195                 200                 205             


Glu Val Gly Lys His Leu Lys His Lys Tyr Glu Thr Ala Leu Lys Val 
    210                 215                 220                 


Gly Ser Thr Thr Asn Glu Ala Ala Gly Glu Ala Gly Ala Ile Ser Pro 
225                 230                 235                 240 


Pro Arg Gly Arg Ala Ser Gly Ala Gly Gly Ser Asp Pro Leu Pro Arg 
                245                 250                 255     


Thr Pro Glu Leu Val His Leu Asp Asp Ser Pro Ser Phe Cys Leu Ala 
            260                 265                 270         


Gly Arg Phe Ser Pro Gly Thr Ala Gly Arg Arg Cys His Arg Glu Lys 
        275                 280                 285             


Asn Cys Glu Ser Ile Cys Cys Gly Arg Gly His Asn Thr Gln Ser Arg 
    290                 295                 300                 


Val Val Thr Arg Pro Cys Gln Cys Gln Val Arg Trp Cys Cys Tyr Val 
305                 310                 315                 320 


Glu Cys Arg Gln Cys Thr Gln Arg Glu Glu Val Tyr Thr Cys Lys Gly 
                325                 330                 335     


<210>  1812
<211>  380
<212>  PRT
<213>  Homo Sapiens

<400>  1812

Glu Glu Gly Leu Asn Phe Pro Thr Tyr Asp Gly Lys Asp Arg Val Val 
1               5                   10                  15      


Ser Leu Ser Glu Lys Asn Phe Lys Gln Val Leu Lys Lys Tyr Asp Leu 
            20                  25                  30          


Leu Cys Leu Tyr Tyr His Glu Pro Val Ser Ser Asp Lys Val Thr Gln 
        35                  40                  45              


Lys Gln Phe Gln Leu Lys Glu Ile Val Leu Glu Leu Val Ala Gln Val 
    50                  55                  60                  


Leu Glu His Lys Ala Ile Gly Phe Val Met Val Asp Ala Lys Lys Glu 
65                  70                  75                  80  


Ala Lys Leu Ala Lys Lys Leu Gly Phe Asp Glu Glu Gly Ser Leu Tyr 
                85                  90                  95      


Ile Leu Lys Gly Asp Arg Thr Ile Glu Phe Asp Gly Glu Phe Ala Ala 
            100                 105                 110         


Asp Val Leu Val Glu Phe Leu Leu Asp Leu Ile Glu Asp Pro Val Glu 
        115                 120                 125             


Ile Ile Ser Ser Lys Leu Glu Val Gln Ala Phe Glu Arg Ile Glu Asp 
    130                 135                 140                 


Tyr Ile Lys Leu Ile Gly Phe Phe Lys Ser Glu Asp Ser Glu Tyr Tyr 
145                 150                 155                 160 


Lys Ala Phe Glu Glu Ala Ala Glu His Phe Gln Pro Tyr Ile Lys Phe 
                165                 170                 175     


Phe Ala Thr Phe Asp Lys Gly Val Ala Lys Lys Leu Ser Leu Lys Met 
            180                 185                 190         


Asn Glu Val Asp Phe Tyr Glu Pro Phe Met Asp Glu Pro Ile Ala Ile 
        195                 200                 205             


Pro Asn Lys Pro Tyr Thr Glu Glu Glu Leu Val Glu Phe Val Lys Glu 
    210                 215                 220                 


His Gln Arg Pro Thr Leu Arg Arg Leu Arg Pro Glu Glu Met Phe Glu 
225                 230                 235                 240 


Thr Trp Glu Asp Asp Leu Asn Gly Ile His Ile Val Ala Phe Ala Glu 
                245                 250                 255     


Lys Ser Asp Pro Asp Gly Tyr Glu Phe Leu Glu Ile Leu Lys Gln Val 
            260                 265                 270         


Ala Arg Asp Asn Thr Asp Asn Pro Asp Leu Ser Ile Leu Trp Ile Asp 
        275                 280                 285             


Pro Asp Asp Phe Pro Leu Leu Val Ala Tyr Trp Glu Lys Thr Phe Lys 
    290                 295                 300                 


Ile Asp Leu Phe Arg Pro Gln Ile Gly Val Val Asn Val Thr Asp Ala 
305                 310                 315                 320 


Asp Ser Val Trp Met Glu Ile Pro Asp Asp Asp Asp Leu Pro Thr Ala 
                325                 330                 335     


Glu Glu Leu Glu Asp Trp Ile Glu Asp Val Leu Ser Gly Lys Ile Asn 
            340                 345                 350         


Thr Glu Asp Asp Asp Glu Asp Asp Asp Asp Asp Asp Asn Ser Asp Glu 
        355                 360                 365             


Glu Asp Asn Asp Asp Ser Asp Asp Asp Asp Asp Glu 
    370                 375                 380 


<210>  1813
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  1813

Gly Pro Trp Ala Asn Ile Cys Ala Gly Lys Ser Ser Asn Glu Ile Arg 
1               5                   10                  15      


Thr Cys Asp Arg His Gly Cys Gly Gln Tyr Ser Ala Gln Arg Ser Gln 
            20                  25                  30          


Arg Pro His Gln Gly Val Asp Val Leu Cys Ser Ala Gly Ser Thr Val 
        35                  40                  45              


Tyr Ala Pro Phe Thr Gly Met Ile Val Gly Gln Glu Lys Pro Tyr Gln 
    50                  55                  60                  


Asn Lys Asn Ala Ile Asn Asn Gly Val Arg Ile Ser Gly Arg Gly Phe 
65                  70                  75                  80  


Cys Val Lys Met Phe Tyr Ile Lys Pro Ile Lys Tyr Lys Gly Pro Ile 
                85                  90                  95      


Lys Lys Gly Glu Lys Leu Gly Thr Leu Leu Pro Leu Gln Lys Val Tyr 
            100                 105                 110         


Pro Gly Ile Gln Ser His Val His Ile Glu Asn Cys Asp Ser Ser Asp 
        115                 120                 125             


Pro Thr Ala Tyr Leu 
    130             


<210>  1814
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  1814

Arg His Gly Gly Arg Thr Val Glu Asn Met Ser Ile Ile Gly Trp Phe 
1               5                   10                  15      


Val Arg Ser Phe Lys Tyr Phe Tyr Gly Leu Arg Phe Glu Val Arg Asp 
            20                  25                  30          


Pro Arg Arg Leu Gln Glu Ala Arg Pro Cys Val Ile Val Ser Asn His 
        35                  40                  45              


Gln Ser Ile Leu Asp Met Met Gly Leu Met Glu Val Leu Pro Glu Arg 
    50                  55                  60                  


Cys Val Gln Ile Ala Lys Arg 
65                  70      


<210>  1815
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  1815

Gly Phe Thr Pro Asp His His Cys Gln Ser Pro Gly Val Ala Glu Leu 
1               5                   10                  15      


Ser Gln Arg Cys Gly Trp Ser Pro Ala Glu Glu Leu Asn Tyr Thr Val 
            20                  25                  30          


Pro Gly Leu Gly Pro Ala Gly Glu Ala Phe Leu Gly Gln Cys Arg Arg 
        35                  40                  45              


Tyr Glu Val Asp Trp Asn Gln Ser Ala Leu Ser Cys Val Asp Pro Leu 
    50                  55                  60                  


Ala Ser Leu Ala Thr Asn Arg Ser His Leu Pro Leu Gly Pro Cys Gln 
65                  70                  75                  80  


Asp Gly Trp Val Tyr Asp Thr Pro Gly Ser Ser Ile Val Thr Glu Phe 
                85                  90                  95      


Asn Leu Val Cys Ala Asp Ser Trp Lys Leu Asp 
            100                 105         


<210>  1816
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  1816

Pro Gly Val Glu Gly Val Thr His Tyr Lys Ala Gly Asp Pro Val Ile 
1               5                   10                  15      


Leu Tyr Val Asn Lys Val Gly Pro Tyr His Asn Pro Gln Glu Thr Tyr 
            20                  25                  30          


His Tyr Tyr Gln Leu Pro Val Cys Cys Pro Glu Lys Ile Arg His Lys 
        35                  40                  45              


Ser Leu Ser Leu Gly Glu Val Leu Asp Gly Asp Arg Met Ala Glu Ser 
    50                  55                  60                  


Leu Tyr Glu Ile Arg Phe Arg Glu Asn Val Glu Lys Arg Ile Leu Cys 
65                  70                  75                  80  


His Met Gln Leu Ser Ser Ala Gln Val Glu Gln Leu Arg Gln Ala Ile 
                85                  90                  95      


Glu Glu Leu Tyr Tyr Phe Glu Phe Val Val Asp Asp Leu Pro Ile Arg 
            100                 105                 110         


Gly Phe Val Gly Tyr Met Glu Glu Ser Gly Phe Leu Pro His Ser His 
        115                 120                 125             


Lys Ile Gly Leu Trp Thr His Leu Asp Phe His Leu Glu Phe His Gly 
    130                 135                 140                 


Asp Arg Ile Ile Phe Ala Asn Val Ser Val Arg Asp Val Lys Pro His 
145                 150                 155                 160 


Ser Leu Asp Gly Leu Arg Pro Asp Glu Phe Leu Gly Leu Thr His Thr 
                165                 170                 175     


Tyr Ser Val Arg Trp Ser Glu Thr Ser Val Glu Arg Arg Ser Asp Arg 
            180                 185                 190         


Arg Arg Gly Asp Asp Gly Gly Phe Phe Pro Arg Thr Leu Glu Ile His 
        195                 200                 205             


Trp 
    


<210>  1817
<211>  387
<212>  PRT
<213>  Homo Sapiens

<400>  1817

Trp Lys Phe Met Gly Ser Lys Cys Ser Asn Ser Gly Ile Glu Cys Asp 
1               5                   10                  15      


Ser Ser Gly Thr Cys Ile Asn Pro Ser Asn Trp Cys Asp Gly Val Ser 
            20                  25                  30          


His Cys Pro Gly Gly Glu Asp Glu Asn Arg Cys Val Arg Leu Tyr Gly 
        35                  40                  45              


Pro Asn Phe Ile Leu Gln Val Tyr Ser Ser Gln Arg Lys Ser Trp His 
    50                  55                  60                  


Pro Val Cys Gln Asp Asp Trp Asn Glu Asn Tyr Gly Arg Ala Ala Cys 
65                  70                  75                  80  


Arg Asp Met Gly Tyr Lys Asn Asn Phe Tyr Ser Ser Gln Gly Ile Val 
                85                  90                  95      


Asp Asp Ser Gly Ser Thr Ser Phe Met Lys Leu Asn Thr Ser Ala Gly 
            100                 105                 110         


Asn Val Asp Ile Tyr Lys Lys Leu Tyr His Ser Asp Ala Cys Ser Ser 
        115                 120                 125             


Lys Ala Val Val Ser Leu Arg Cys Ile Ala Cys Gly Val Asn Leu Asn 
    130                 135                 140                 


Ser Ser Arg Gln Ser Arg Ile Val Gly Gly Glu Ser Ala Leu Pro Gly 
145                 150                 155                 160 


Ala Trp Pro Trp Gln Val Ser Leu His Val Gln Asn Val His Val Cys 
                165                 170                 175     


Gly Gly Ser Ile Ile Thr Pro Glu Trp Ile Val Thr Ala Ala His Cys 
            180                 185                 190         


Val Glu Lys Pro Leu Asn Asn Pro Trp His Trp Thr Ala Phe Ala Gly 
        195                 200                 205             


Ile Leu Arg Gln Ser Phe Met Phe Tyr Gly Ala Gly Tyr Gln Val Glu 
    210                 215                 220                 


Lys Val Ile Ser His Pro Asn Tyr Asp Ser Lys Thr Lys Asn Asn Asp 
225                 230                 235                 240 


Ile Ala Leu Met Lys Leu Gln Lys Pro Leu Thr Phe Asn Asp Leu Val 
                245                 250                 255     


Lys Pro Val Cys Leu Pro Asn Pro Gly Met Met Leu Gln Pro Glu Gln 
            260                 265                 270         


Leu Cys Trp Ile Ser Gly Trp Gly Ala Thr Glu Glu Lys Gly Lys Thr 
        275                 280                 285             


Ser Glu Val Leu Asn Ala Ala Lys Val Leu Leu Ile Glu Thr Gln Arg 
    290                 295                 300                 


Cys Asn Ser Arg Tyr Val Tyr Asp Asn Leu Ile Thr Pro Ala Met Ile 
305                 310                 315                 320 


Cys Ala Gly Phe Leu Gln Gly Asn Val Asp Ser Cys Gln Gly Asp Ser 
                325                 330                 335     


Gly Gly Pro Leu Val Thr Ser Lys Asn Asn Ile Trp Trp Leu Ile Gly 
            340                 345                 350         


Asp Thr Ser Trp Gly Ser Gly Cys Ala Lys Ala Tyr Arg Pro Gly Val 
        355                 360                 365             


Tyr Gly Asn Val Met Val Phe Thr Asp Trp Ile Tyr Arg Gln Met Arg 
    370                 375                 380                 


Ala Asp Gly 
385         


<210>  1818
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  1818

Met Asp His Ser His His Met Gly Met Ser Tyr Met Asp Ser Asn Ser 
1               5                   10                  15      


Thr Met Gln Pro Ser His His His Pro Thr Thr Ser Ala Ser His Ser 
            20                  25                  30          


His Gly Gly Gly Asp Ser Ser Met Met Met Met Pro Met Thr Phe Tyr 
        35                  40                  45              


Phe Gly Phe Lys Asn Val Glu Leu Leu Phe Ser Gly Leu 
    50                  55                  60      


<210>  1819
<211>  512
<212>  PRT
<213>  Homo Sapiens

<400>  1819

Glu Phe Phe Thr Ser Ile Gly His Met Thr Asp Leu Ile Tyr Ala Glu 
1               5                   10                  15      


Lys Glu Leu Val Gln Ser Leu Lys Glu Tyr Ile Leu Val Glu Glu Ala 
            20                  25                  30          


Lys Leu Ser Lys Ile Lys Ser Trp Ala Asn Lys Met Glu Ala Leu Thr 
        35                  40                  45              


Ser Lys Ser Ala Ala Asp Ala Glu Gly Tyr Leu Ala His Pro Val Asn 
    50                  55                  60                  


Ala Tyr Lys Leu Val Lys Arg Leu Asn Thr Asp Trp Pro Ala Leu Glu 
65                  70                  75                  80  


Asp Leu Val Leu Gln Asp Ser Ala Ala Gly Phe Ile Ala Asn Leu Ser 
                85                  90                  95      


Val Gln Arg Gln Phe Phe Pro Thr Asp Glu Asp Glu Ile Gly Ala Ala 
            100                 105                 110         


Lys Ala Leu Met Arg Leu Gln Asp Thr Tyr Arg Leu Asp Pro Gly Thr 
        115                 120                 125             


Ile Ser Arg Gly Glu Leu Pro Gly Thr Lys Tyr Gln Ala Met Leu Ser 
    130                 135                 140                 


Val Asp Asp Cys Phe Gly Met Gly Arg Ser Ala Tyr Asn Glu Gly Asp 
145                 150                 155                 160 


Tyr Tyr His Thr Val Leu Trp Met Glu Gln Val Leu Lys Gln Leu Asp 
                165                 170                 175     


Ala Gly Glu Glu Ala Thr Thr Thr Lys Ser Gln Val Leu Asp Tyr Leu 
            180                 185                 190         


Ser Tyr Ala Val Phe Gln Leu Gly Asp Leu His Arg Ala Leu Glu Leu 
        195                 200                 205             


Thr Arg Arg Leu Leu Ser Leu Asp Pro Ser His Glu Arg Ala Gly Gly 
    210                 215                 220                 


Asn Leu Arg Tyr Phe Glu Gln Leu Leu Glu Glu Glu Arg Glu Lys Thr 
225                 230                 235                 240 


Leu Thr Asn Gln Thr Glu Ala Glu Leu Ala Thr Pro Glu Gly Ile Tyr 
                245                 250                 255     


Glu Arg Pro Val Asp Tyr Leu Pro Glu Arg Asp Val Tyr Glu Ser Leu 
            260                 265                 270         


Cys Arg Gly Glu Gly Val Lys Leu Thr Pro Arg Arg Gln Lys Arg Leu 
        275                 280                 285             


Phe Cys Arg Tyr His His Gly Asn Arg Ala Pro Gln Leu Leu Ile Ala 
    290                 295                 300                 


Pro Phe Lys Glu Glu Asp Glu Trp Asp Ser Pro His Ile Val Arg Tyr 
305                 310                 315                 320 


Tyr Asp Val Met Ser Asp Glu Glu Ile Glu Arg Ile Lys Glu Ile Ala 
                325                 330                 335     


Lys Pro Lys Leu Ala Arg Ala Thr Val Arg Asp Pro Lys Thr Gly Val 
            340                 345                 350         


Leu Thr Val Ala Ser Tyr Arg Val Ser Lys Ser Ser Trp Leu Glu Glu 
        355                 360                 365             


Asp Asp Asp Pro Val Val Ala Arg Val Asn Arg Arg Met Gln His Ile 
    370                 375                 380                 


Thr Gly Leu Thr Val Lys Thr Ala Glu Leu Leu Gln Val Ala Asn Tyr 
385                 390                 395                 400 


Gly Val Gly Gly Gln Tyr Glu Pro His Phe Asp Phe Ser Arg Arg Pro 
                405                 410                 415     


Phe Asp Ser Gly Leu Lys Thr Glu Gly Asn Arg Leu Ala Thr Phe Leu 
            420                 425                 430         


Asn Tyr Met Ser Asp Val Glu Ala Gly Gly Ala Thr Val Phe Pro Asp 
        435                 440                 445             


Leu Gly Ala Ala Ile Trp Pro Lys Lys Gly Thr Ala Val Phe Trp Tyr 
    450                 455                 460                 


Asn Leu Leu Arg Ser Gly Glu Gly Asp Tyr Arg Thr Arg His Ala Ala 
465                 470                 475                 480 


Cys Pro Val Leu Val Gly Cys Lys Trp Val Ser Asn Lys Trp Phe His 
                485                 490                 495     


Glu Arg Gly Gln Glu Phe Leu Arg Pro Cys Gly Ser Thr Glu Val Asp 
            500                 505                 510         


<210>  1820
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  1820

Gly Ile Leu Glu Leu Ala Gly Thr Val Gly Cys Val Gly Pro Arg Thr 
1               5                   10                  15      


Pro Ile Ala Tyr Met Lys Tyr Gly Cys Phe Cys Gly Leu Gly Gly His 
            20                  25                  30          


Gly Gln Pro Arg Asp Ala Ile Asp Trp Cys Cys His Gly His Asp Cys 
        35                  40                  45              


Cys Tyr Thr Arg Ala Glu Glu Ala Gly Cys Ser Pro Lys Thr Glu Arg 
    50                  55                  60                  


Tyr Ser Trp Gln Cys Val Asn Gln Ser Val Leu Cys Gly Pro Ala Glu 
65                  70                  75                  80  


Asn Lys Cys Gln Glu Leu Leu Cys Lys Cys Asp Gln Glu Ile Ala Asn 
                85                  90                  95      


Cys Leu Ala Gln Thr Glu Tyr Asn Leu Lys Tyr Leu Phe Tyr Pro Gln 
            100                 105                 110         


Phe Leu Cys Glu Pro Asp Ser Pro Lys Cys Asp 
        115                 120             


<210>  1821
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  1821

Ser Thr Glu Asp Glu Gly Glu Asp Pro Trp Tyr Gln Lys Ala Cys Lys 
1               5                   10                  15      


Cys Asp Cys Gln Gly Gly Pro Asn Ala Leu Trp Ser Ala Gly Ala Thr 
            20                  25                  30          


Ser Leu Asp Cys Ile Pro Glu Cys Pro Tyr His Lys Pro Leu Gly Phe 
        35                  40                  45              


Glu Ser Gly Glu Val Thr Pro Asp Gln Ile Thr Cys Ser Asn Pro Glu 
    50                  55                  60                  


Gln Tyr Val Gly Trp Tyr Ser Ser Trp Thr Ala Asn Lys Ala Arg Leu 
65                  70                  75                  80  


Asn Ser Gln Gly Phe Gly Cys Ala Trp Leu Ser Lys Phe Gln Asp Ser 
                85                  90                  95      


Ser Gln Trp Leu Gln Ile Asp Leu Lys Glu Ile Lys Val Ile Ser Gly 
            100                 105                 110         


Ile Leu Thr Gln Gly Arg Cys Asp Ile Asp Glu Trp Met Thr Lys Tyr 
        115                 120                 125             


Ser Val Gln Tyr Arg Thr Asp Glu Arg Leu Asn Trp Ile Tyr Tyr Lys 
    130                 135                 140                 


Asp Gln Thr Gly Asn Asn Arg Val Phe Tyr Gly Asn Ser Asp Arg Thr 
145                 150                 155                 160 


Ser Thr Val Gln Asn Leu Leu Arg Pro Pro Ile Ile Ser Arg Phe Ile 
                165                 170                 175     


Arg Leu Ile Pro Leu Gly Trp His Val Arg Ile Ala Ile Arg Met Glu 
            180                 185                 190         


Leu Leu Glu Cys Val Ser Lys Cys Ala 
        195                 200     


<210>  1822
<211>  273
<212>  PRT
<213>  Homo Sapiens

<400>  1822

Lys Lys Gly Tyr Gln Glu Arg Asp Leu Glu Pro Gln Phe Ser Ile Ile 
1               5                   10                  15      


Thr Lys Leu Lys Gly Val Ser Val Thr Gln Ile Lys Glu Leu Gly Asn 
            20                  25                  30          


Arg Leu Trp Asp Val Ala Asp Phe Val Lys Pro Pro Gln Gly Glu Asn 
        35                  40                  45              


Val Phe Phe Leu Val Thr Asn Phe Leu Val Thr Pro Ala Gln Val Gln 
    50                  55                  60                  


Gly Arg Cys Pro Glu His Pro Ser Val Pro Leu Ala Asn Cys Trp Val 
65                  70                  75                  80  


Asp Glu Asp Cys Pro Glu Gly Glu Gly Gly Thr His Ser His Gly Val 
                85                  90                  95      


Lys Thr Gly Gln Cys Val Val Phe Asn Gly Thr His Arg Thr Cys Glu 
            100                 105                 110         


Ile Trp Ser Trp Cys Pro Val Glu Ser Gly Val Val Pro Ser Arg Pro 
        115                 120                 125             


Leu Leu Ala Gln Ala Gln Asn Phe Thr Leu Phe Ile Lys Asn Thr Val 
    130                 135                 140                 


Thr Phe Ser Lys Phe Asn Phe Ser Lys Ser Asn Ala Leu Glu Thr Trp 
145                 150                 155                 160 


Asp Pro Thr Tyr Phe Lys His Cys Arg Tyr Glu Pro Gln Phe Ser Pro 
                165                 170                 175     


Tyr Cys Pro Val Phe Arg Ile Gly Asp Leu Val Ala Lys Ala Gly Gly 
            180                 185                 190         


Thr Phe Glu Asp Leu Ala Leu Leu Gly Gly Ser Val Gly Ile Arg Val 
        195                 200                 205             


His Trp Asp Cys Asp Leu Asp Thr Gly Asp Ser Gly Cys Trp Pro His 
    210                 215                 220                 


Tyr Ser Phe Gln Leu Gln Glu Lys Ser Tyr Asn Phe Arg Thr Ala Thr 
225                 230                 235                 240 


His Trp Trp Glu Gln Pro Gly Val Glu Ala Arg Thr Leu Leu Lys Leu 
                245                 250                 255     


Tyr Gly Ile Arg Phe Asp Ile Leu Val Thr Gly Gln Ala Gly Lys Phe 
            260                 265                 270         


Gly 
    


<210>  1823
<211>  51
<212>  PRT
<213>  Homo Sapiens

<400>  1823

Arg Val Ser Ala Phe Ile Gly Ser Asn Ile Ile Thr Ser Gln Asn Ile 
1               5                   10                  15      


Trp Glu Gly Leu Trp Met Asn Cys Val Val Gln Ser Thr Gly Gln Met 
            20                  25                  30          


Gln Cys Lys Val Tyr Asp Ser Leu Leu Ala Leu Pro Gln Asp Leu Gln 
        35                  40                  45              


Ala Ala Arg 
    50      


<210>  1824
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  1824

Ala Glu Ala Ala Leu Leu Pro Gln Asn Asp Thr Arg Leu Asp Pro Glu 
1               5                   10                  15      


Ala Tyr Gly Ala Pro Cys Ala Arg Gly Ser Gln Pro Trp Gln Val Ser 
            20                  25                  30          


Leu Phe Asn Gly Leu Ser Phe His Cys Ala Gly Val Leu Val Asp Gln 
        35                  40                  45              


Ser Trp Val Leu Thr Ala Ala His Cys Gly Asn Lys Pro Leu Trp Ala 
    50                  55                  60                  


Arg Val Gly Asp Asp His Leu Leu Leu Leu Gln Gly Glu Gln Leu Arg 
65                  70                  75                  80  


Arg Thr Thr Arg Ser Val Val His Pro Lys Tyr His Gln Gly Ser Gly 
                85                  90                  95      


Pro Ile Leu Pro Arg Arg Thr Asp Glu His Asp Leu Met Leu Leu Lys 
            100                 105                 110         


Leu Ala Arg Pro Val Val Pro Gly Pro Arg Val Arg Ala Leu Gln Leu 
        115                 120                 125             


Pro Tyr Arg Cys Ala Gln Pro Gly Asp Gln Cys Gln Val Ala Gly Trp 
    130                 135                 140                 


Gly Thr Thr Ala Ala Arg Arg Val Lys Tyr Asn Lys Gly Leu Thr Cys 
145                 150                 155                 160 


Ser Ser Ile Thr Ile Leu Ser Pro Lys Glu Cys Glu Val Phe Tyr Pro 
                165                 170                 175     


Gly Val Val Thr Asn Asn Met Ile Cys Ala Gly Leu Asp Arg Gly Gln 
            180                 185                 190         


Asp Pro Cys Gln Ser Asp Ser Gly Gly Pro Leu Val Cys Asp Glu Thr 
        195                 200                 205             


Leu Gln Gly Ile Leu Ser Trp Gly Val Tyr Pro Cys Gly Ser Ala Gln 
    210                 215                 220                 


His Pro Ala Val Tyr Thr Gln Ile Cys Lys Tyr Met Ser Trp Ile Asn 
225                 230                 235                 240 


Lys Val Ile Arg Ser Asn 
                245     


<210>  1825
<211>  502
<212>  PRT
<213>  Homo Sapiens

<400>  1825

Leu Pro Pro Pro Cys Glu Ser Glu Ile Tyr Cys His Gly Glu Leu Leu 
1               5                   10                  15      


Asn Gln Val Gln Met Ala Lys Leu Tyr Gln Asp Asp Lys Gln Phe Val 
            20                  25                  30          


Asp Met Pro Leu Ser Ile Ala Pro Glu Gln Val Leu Gln Thr Phe Thr 
        35                  40                  45              


Glu Leu Ser Arg Asp His Asn His Ser Ile Pro Arg Glu Gln Leu Gln 
    50                  55                  60                  


Ala Phe Val His Glu His Phe Gln Ala Lys Gly Gln Glu Leu Gln Pro 
65                  70                  75                  80  


Trp Thr Pro Ala Asp Trp Lys Asp Ser Pro Gln Phe Leu Gln Lys Ile 
                85                  90                  95      


Ser Asp Ala Lys Leu Arg Ala Trp Ala Gly Gln Leu His Gln Leu Trp 
            100                 105                 110         


Lys Lys Leu Gly Lys Lys Met Lys Pro Glu Val Leu Ser His Pro Glu 
        115                 120                 125             


Arg Phe Ser Leu Ile Tyr Ser Glu His Pro Phe Ile Val Pro Gly Gly 
    130                 135                 140                 


Arg Phe Val Glu Phe Tyr Tyr Cys Tyr Gly His Val Pro Asn Gly Gly 
145                 150                 155                 160 


Arg Val Tyr Tyr Leu Gln Arg Ser Gln Pro Pro Leu Leu Thr Leu Met 
                165                 170                 175     


Met Asp Cys Tyr Leu Thr His Thr Asn Asp Thr Ala Phe Leu Gln Glu 
            180                 185                 190         


Asn Ile Glu Thr Leu Ala Leu Glu Leu Asp Phe Trp Thr Lys Asn Arg 
        195                 200                 205             


Thr Val Ser Val Ser Leu Glu Gly Lys Asn Tyr Leu Leu Asn Arg Tyr 
    210                 215                 220                 


Tyr Val Pro Tyr Gly Gly Pro Arg Pro Glu Ser Tyr Ser Lys Asp Val 
225                 230                 235                 240 


Glu Leu Ala Asp Thr Leu Pro Glu Gly Asp Arg Glu Ala Leu Trp Ala 
                245                 250                 255     


Glu Leu Lys Ala Gly Ala Glu Ser Gly Trp Asp Phe Ser Ser Arg Trp 
            260                 265                 270         


Leu Ile Gly Gly Pro Asn Pro Asn Ser Leu Ser Gly Ile Arg Thr Ser 
        275                 280                 285             


Lys Leu Val Pro Val Asp Leu Asn Ala Phe Leu Cys Gln Ala Glu Glu 
    290                 295                 300                 


Leu Met Ser Asn Phe Tyr Ser Arg Leu Gly Asn Asp Ser Gln Ala Thr 
305                 310                 315                 320 


Lys Tyr Arg Ile Leu Arg Ser Gln Arg Leu Ala Ala Leu Asn Thr Val 
                325                 330                 335     


Leu Trp Asp Glu Gln Thr Gly Ala Trp Phe Asp Tyr Asp Leu Glu Lys 
            340                 345                 350         


Lys Lys Lys Asn Arg Glu Phe Tyr Pro Ser Asn Leu Thr Pro Leu Trp 
        355                 360                 365             


Ala Gly Cys Phe Ser Asp Pro Gly Val Ala Asp Lys Ala Leu Lys Tyr 
    370                 375                 380                 


Leu Glu Asp Asn Arg Ile Leu Thr Tyr Gln Tyr Gly Ile Pro Thr Ser 
385                 390                 395                 400 


Leu Gln Lys Thr Gly Gln Gln Trp Asp Phe Pro Asn Ala Trp Ala Pro 
                405                 410                 415     


Leu Gln Asp Leu Val Ile Arg Gly Leu Ala Lys Ala Pro Leu Arg Arg 
            420                 425                 430         


Ala Gln Glu Val Ala Phe Gln Leu Ala Gln Asn Trp Ile Arg Thr Asn 
        435                 440                 445             


Phe Asp Val Tyr Ser Gln Lys Ser Ala Met Tyr Glu Lys Tyr Asp Val 
    450                 455                 460                 


Ser Asn Gly Gly Gln Pro Gly Gly Gly Gly Glu Tyr Glu Val Gln Glu 
465                 470                 475                 480 


Gly Phe Gly Trp Thr Asn Gly Val Val Leu Met Leu Leu Asp Arg Tyr 
                485                 490                 495     


Gly Asp Arg Leu Thr Ser 
            500         


<210>  1826
<211>  170
<212>  PRT
<213>  Homo Sapiens

<400>  1826

Ala Asp Arg Glu Arg Ser Ile His Asp Phe Cys Leu Val Ser Lys Val 
1               5                   10                  15      


Val Gly Arg Cys Arg Ala Ser Met Pro Arg Trp Trp Tyr Asn Val Thr 
            20                  25                  30          


Asp Gly Ser Cys Gln Leu Phe Val Tyr Gly Gly Cys Asp Gly Asn Ser 
        35                  40                  45              


Asn Asn Tyr Leu Thr Lys Glu Glu Cys Leu Lys Lys Cys Ala Thr Val 
    50                  55                  60                  


Thr Glu Asn Ala Thr Gly Asp Leu Ala Thr Ser Arg Asn Ala Ala Asp 
65                  70                  75                  80  


Ser Ser Val Pro Ser Ala Pro Arg Arg Gln Asp Ser Glu Asp His Ser 
                85                  90                  95      


Ser Asp Met Phe Asn Tyr Glu Glu Tyr Cys Thr Ala Asn Ala Val Thr 
            100                 105                 110         


Gly Pro Cys Arg Ala Ser Phe Pro Arg Trp Tyr Phe Asp Val Glu Arg 
        115                 120                 125             


Asn Ser Cys Asn Asn Phe Ile Tyr Gly Gly Cys Arg Gly Asn Lys Asn 
    130                 135                 140                 


Ser Tyr Arg Ser Glu Glu Ala Cys Met Leu Arg Cys Phe Arg Gln Gln 
145                 150                 155                 160 


Glu Asn Pro Pro Leu Pro Leu Gly Ser Lys 
                165                 170 


<210>  1827
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  1827

Cys Gly Pro Gly Arg Gly Pro Val Gly Arg Arg Arg Tyr Ala Arg Lys 
1               5                   10                  15      


Gln Leu Val Pro Leu Leu Tyr Lys Gln Phe Val Pro Gly Val Pro Glu 
            20                  25                  30          


Arg Thr Leu Gly Ala Ser Gly Pro Ala Glu Gly Arg Val Ala Arg Gly 
        35                  40                  45              


Ser Glu Arg Phe Arg Asp Leu Val Pro Asn Tyr Asn Pro Asp Ile Ile 
    50                  55                  60                  


Phe Lys Asp Glu Glu Asn Ser Gly Ala Asp Arg Leu Met Thr Glu Arg 
65                  70                  75                  80  


Cys Lys Glu Arg Val Asn Ala Leu Ala Ile Ala Val Met Asn Met Trp 
                85                  90                  95      


Pro Gly Val Arg Leu Arg Val Thr Glu Gly Trp Asp Glu Asp Gly His 
            100                 105                 110         


His Ala Gln Asp Ser Leu His Tyr Glu Gly Arg Ala Leu Asp Ile Thr 
        115                 120                 125             


Thr Ser Asp Arg Asp Arg Asn Lys Tyr Gly Leu Leu Ala Arg Leu Ala 
    130                 135                 140                 


Val Glu Ala Gly Phe Asp Trp Val Tyr Tyr Glu Ser Arg Asn His Val 
145                 150                 155                 160 


His Val Ser Val Lys Ala Asp Asn Ser Leu Ala Val Arg Ala Gly Gly 
                165                 170                 175     


<210>  1828
<211>  360
<212>  PRT
<213>  Homo Sapiens

<400>  1828

Ala Thr Glu Ser Val Lys Gln Glu Asp Ala Gly Val Arg Pro Ser Ala 
1               5                   10                  15      


Gly Asn Val Ser Thr His Pro Ser Leu Ser Gln Arg Pro Gly Gly Ser 
            20                  25                  30          


Thr Lys Ser His Pro Glu Pro Gln Thr Pro Lys Asp Ser Pro Ser Lys 
        35                  40                  45              


Ser Ser Ala Glu Ala Gln Thr Pro Glu Asp Thr Pro Asn Lys Ser Gly 
    50                  55                  60                  


Ala Glu Ala Lys Thr Gln Lys Asp Ser Ser Asn Lys Ser Gly Ala Glu 
65                  70                  75                  80  


Ala Lys Thr Gln Lys Gly Ser Thr Ser Lys Ser Gly Ser Glu Ala Gln 
                85                  90                  95      


Thr Thr Lys Asp Ser Thr Ser Lys Ser His Pro Glu Leu Gln Thr Pro 
            100                 105                 110         


Lys Asp Ser Thr Gly Lys Ser Gly Ala Glu Ala Gln Thr Pro Glu Asp 
        115                 120                 125             


Ser Pro Asn Arg Ser Gly Ala Glu Ala Lys Thr Gln Lys Asp Ser Pro 
    130                 135                 140                 


Ser Lys Ser Gly Ser Glu Ala Gln Thr Thr Lys Asp Val Pro Asn Lys 
145                 150                 155                 160 


Ser Gly Ala Asp Gly Gln Thr Pro Lys Asp Gly Ser Ser Lys Ser Gly 
                165                 170                 175     


Ala Glu Asp Gln Thr Pro Lys Asp Val Pro Asn Lys Ser Gly Ala Glu 
            180                 185                 190         


Lys Gln Thr Pro Lys Asp Gly Ser Asn Lys Ser Gly Ala Glu Glu Gln 
        195                 200                 205             


Gly Pro Ile Asp Gly Pro Ser Lys Ser Gly Ala Glu Glu Gln Thr Ser 
    210                 215                 220                 


Lys Asp Ser Pro Asn Lys Val Val Pro Glu Gln Pro Ser Arg Lys Asp 
225                 230                 235                 240 


His Ser Lys Pro Ile Ser Asn Pro Ser Asp Asn Lys Glu Leu Pro Lys 
                245                 250                 255     


Ala Asp Thr Asn Gln Leu Ala Asp Lys Gly Lys Leu Ser Pro His Ala 
            260                 265                 270         


Phe Lys Thr Glu Ser Gly Glu Glu Thr Asp Leu Ile Ser Pro Pro Gln 
        275                 280                 285             


Glu Glu Val Lys Ser Ser Glu Pro Thr Glu Asp Val Glu Pro Lys Glu 
    290                 295                 300                 


Ala Glu Asp Asp Asp Thr Gly Pro Glu Glu Gly Ser Pro Pro Lys Glu 
305                 310                 315                 320 


Glu Lys Glu Lys Met Ser Gly Ser Ala Ser Ser Glu Asn Arg Glu Gly 
                325                 330                 335     


Thr Leu Ser Asp Ser Thr Gly Ser Glu Lys Asp Asp Leu Tyr Pro Asn 
            340                 345                 350         


Gly Ser Gly Asn Gly Ser Ala Glu 
        355                 360 


<210>  1829
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  1829

Gln His Trp Ser His Gly Trp Tyr Pro Gly Gly Lys Arg Ala Leu Ser 
1               5                   10                  15      


Ser Ala Gln Asp Pro Gln Asn Ala Leu Arg Pro Pro Gly Arg Ala Leu 
            20                  25                  30          


Asp Thr Ala Ala Gly Ser Pro Val Gln Thr Ala His Gly Leu Pro Ser 
        35                  40                  45              


Asp Ala Leu Ala Pro Leu Asp Asp Ser Met Pro Trp Glu Gly Arg Thr 
    50                  55                  60                  


Thr Ala Gln Trp Ser Leu His Arg Lys Arg His Leu Ala Arg Thr Leu 
65                  70                  75                  80  


Leu Thr Ala Ala Arg Glu Pro Arg Pro Ala Pro Pro Ser Ser Asn Lys 
                85                  90                  95      


Val 
    


<210>  1830
<211>  317
<212>  PRT
<213>  Homo Sapiens

<400>  1830

Met Gln Leu Pro Arg Trp Trp Glu Leu Gly Asp Pro Cys Ala Trp Thr 
1               5                   10                  15      


Gly Gln Gly Arg Gly Thr Arg Arg Met Ser Pro Ala Thr Thr Gly Thr 
            20                  25                  30          


Phe Leu Leu Thr Val Tyr Ser Ile Phe Ser Lys Val His Ser Asp Arg 
        35                  40                  45              


Ser Val Tyr Pro Ser Ala Gly Val Leu Phe Val His Val Leu Glu Arg 
    50                  55                  60                  


Glu Tyr Phe Lys Gly Glu Phe Pro Pro Tyr Pro Lys Pro Gly Glu Ile 
65                  70                  75                  80  


Ser Asn Asp Pro Ile Thr Phe Asn Thr Asn Leu Met Gly Tyr Pro Asp 
                85                  90                  95      


Arg Pro Gly Trp Leu Arg Tyr Ile Gln Arg Thr Pro Tyr Ser Asp Gly 
            100                 105                 110         


Val Leu Tyr Gly Ser Pro Thr Ala Glu Asn Val Gly Lys Pro Thr Ile 
        115                 120                 125             


Ile Glu Ile Thr Ala Tyr Asn Arg Arg Thr Phe Glu Thr Ala Arg His 
    130                 135                 140                 


Asn Leu Ile Ile Asn Ile Met Ser Ala Glu Asp Phe Pro Leu Pro Tyr 
145                 150                 155                 160 


Gln Ala Glu Phe Phe Ile Lys Asn Met Asn Val Glu Glu Met Leu Ala 
                165                 170                 175     


Ser Glu Val Leu Gly Asp Phe Leu Gly Ala Val Lys Asn Val Trp Gln 
            180                 185                 190         


Pro Glu Arg Leu Asn Ala Ile Asn Ile Thr Ser Ala Leu Asp Arg Gly 
        195                 200                 205             


Gly Arg Val Pro Leu Pro Ile Asn Asp Leu Lys Glu Gly Val Tyr Val 
    210                 215                 220                 


Met Val Gly Ala Asp Val Pro Phe Ser Ser Cys Leu Arg Glu Val Glu 
225                 230                 235                 240 


Asn Pro Gln Asn Gln Leu Arg Cys Ser Gln Glu Met Glu Pro Val Ile 
                245                 250                 255     


Thr Cys Asp Lys Lys Phe Arg Thr Gln Phe Tyr Ile Asp Trp Cys Lys 
            260                 265                 270         


Ile Ser Leu Val Asp Lys Thr Lys Gln Val Ser Thr Tyr Gln Glu Val 
        275                 280                 285             


Ile Arg Gly Glu Gly Ile Leu Pro Asp Gly Gly Glu Tyr Lys Pro Pro 
    290                 295                 300                 


Ser Asp Ser Leu Lys Ser Arg Asp Tyr Tyr Thr Asp Phe 
305                 310                 315         


<210>  1831
<211>  277
<212>  PRT
<213>  Homo Sapiens

<400>  1831

Ala Pro Val Asn Gly Ser Lys Trp Thr Tyr Phe Gly Pro Asp Gly Glu 
1               5                   10                  15      


Asn Ser Trp Ser Lys Lys Tyr Pro Ser Cys Gly Gly Leu Leu Gln Ser 
            20                  25                  30          


Pro Ile Asp Leu His Ser Asp Ile Leu Gln Tyr Asp Ala Ser Leu Thr 
        35                  40                  45              


Pro Leu Glu Phe Gln Gly Tyr Asn Leu Ser Ala Asn Lys Gln Phe Leu 
    50                  55                  60                  


Leu Thr Asn Asn Gly His Ser Val Lys Leu Asn Leu Pro Ser Asp Met 
65                  70                  75                  80  


His Ile Gln Gly Leu Gln Ser Arg Tyr Ser Ala Thr Gln Leu His Leu 
                85                  90                  95      


His Trp Gly Asn Pro Asn Asp Pro His Gly Ser Glu His Thr Val Ser 
            100                 105                 110         


Gly Gln His Phe Ala Ala Glu Leu His Ile Val His Tyr Asn Ser Asp 
        115                 120                 125             


Leu Tyr Pro Asp Ala Ser Thr Ala Ser Asn Lys Ser Glu Gly Leu Ala 
    130                 135                 140                 


Val Leu Ala Val Leu Ile Glu Met Gly Ser Phe Asn Pro Ser Tyr Asp 
145                 150                 155                 160 


Lys Ile Phe Ser His Leu Gln His Val Lys Tyr Lys Gly Gln Glu Ala 
                165                 170                 175     


Phe Val Pro Gly Phe Asn Ile Glu Glu Leu Leu Pro Glu Arg Thr Ala 
            180                 185                 190         


Glu Tyr Tyr Arg Tyr Arg Gly Ser Leu Thr Thr Pro Pro Cys Asn Pro 
        195                 200                 205             


Thr Val Leu Trp Thr Val Phe Arg Asn Pro Val Gln Ile Ser Gln Glu 
    210                 215                 220                 


Gln Leu Leu Ala Leu Glu Thr Ala Leu Tyr Cys Thr His Met Asp Asp 
225                 230                 235                 240 


Pro Ser Pro Arg Glu Met Ile Asn Asn Phe Arg Gln Val Gln Lys Phe 
                245                 250                 255     


Asp Glu Arg Leu Val Tyr Thr Ser Phe Ser Gln Val Gln Val Cys Thr 
            260                 265                 270         


Ala Ala Gly Leu Ser 
        275         


<210>  1832
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  1832

Met Ser Gly Thr Lys Leu Glu Asp Ser Pro Pro Cys Arg Asn Trp Ser 
1               5                   10                  15      


Ser Ala Ser Glu Leu Asn Glu Thr Gln Glu Pro Phe Leu Asn Pro Thr 
            20                  25                  30          


Asp Tyr Asp Asp Glu Glu Phe Leu Arg Tyr Leu Trp Arg Glu Tyr Leu 
        35                  40                  45              


His Pro Lys Glu Tyr Glu 
    50                  


<210>  1833
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  1833

Tyr Ile Ser Gln Asn Asp Met Ile Ala Ile Leu Asp Tyr His Asn Gln 
1               5                   10                  15      


Val Arg Gly Lys Val Phe Pro Pro Ala Ala Asn Met Glu Tyr Met Val 
            20                  25                  30          


Trp Asp Glu Asn Leu Ala Lys Ser Ala Glu Ala Trp Ala Ala Thr Cys 
        35                  40                  45              


Ile Trp Asp His Gly Pro Ser Tyr Leu Leu Arg Phe Leu Gly Gln Asn 
    50                  55                  60                  


Leu Ser Val Arg Thr Gly Arg Tyr Arg Ser Ile Leu Gln Leu Val Lys 
65                  70                  75                  80  


Pro Trp Tyr Asp Glu Val Lys Asp Tyr Ala Phe Pro Tyr Pro Gln Asp 
                85                  90                  95      


Cys Asn Pro Arg Cys Pro Met Arg Cys Phe Gly Pro Met Cys Thr His 
            100                 105                 110         


Tyr Thr Gln Met Val Trp Ala Thr Ser Asn Arg Ile Gly Cys Ala Ile 
        115                 120                 125             


His Thr Cys Gln Asn Met Asn Val Trp Gly Ser Val Trp Arg Arg Ala 
    130                 135                 140                 


Val Tyr Leu Val Cys Asn Tyr Ala Pro Lys Gly Asn Trp Ile Gly Glu 
145                 150                 155                 160 


Ala Pro Tyr Lys Val Gly Val Pro Cys Ser Ser Cys Pro Pro Ser Tyr 
                165                 170                 175     


Gly Gly Ser Cys Thr Asp Asn Leu Cys Phe Pro Gly Val Thr Ser Asn 
            180                 185                 190         


Tyr Leu Tyr Trp Phe Lys 
        195             


<210>  1834
<211>  296
<212>  PRT
<213>  Homo Sapiens

<400>  1834

Lys Pro Thr Glu Lys Lys Asp Arg Val His His Glu Pro Gln Leu Ser 
1               5                   10                  15      


Asp Lys Val His Asn Asp Ala Gln Ser Phe Asp Tyr Asp His Asp Ala 
            20                  25                  30          


Phe Leu Gly Ala Glu Glu Ala Lys Thr Phe Asp Gln Leu Thr Pro Glu 
        35                  40                  45              


Glu Ser Lys Glu Arg Leu Gly Lys Ile Val Ser Lys Ile Asp Gly Asp 
    50                  55                  60                  


Lys Asp Gly Phe Val Thr Val Asp Glu Leu Lys Asp Trp Ile Lys Phe 
65                  70                  75                  80  


Ala Gln Lys Arg Trp Ile Tyr Glu Asp Val Glu Arg Gln Trp Lys Gly 
                85                  90                  95      


His Asp Leu Asn Glu Asp Gly Leu Val Ser Trp Glu Glu Tyr Lys Asn 
            100                 105                 110         


Ala Thr Tyr Gly Tyr Val Leu Asp Asp Pro Asp Pro Asp Asp Gly Phe 
        115                 120                 125             


Asn Tyr Lys Gln Met Met Val Arg Asp Glu Arg Arg Phe Lys Met Ala 
    130                 135                 140                 


Asp Lys Asp Gly Asp Leu Ile Ala Thr Lys Glu Glu Phe Thr Ala Phe 
145                 150                 155                 160 


Leu His Pro Glu Glu Tyr Asp Tyr Met Lys Asp Ile Val Val Gln Glu 
                165                 170                 175     


Thr Met Glu Asp Ile Asp Lys Asn Ala Asp Gly Phe Ile Asp Leu Glu 
            180                 185                 190         


Glu Tyr Ile Gly Asp Met Tyr Ser His Asp Gly Asn Thr Asp Glu Pro 
        195                 200                 205             


Glu Trp Val Lys Thr Glu Arg Glu Gln Phe Val Glu Phe Arg Asp Lys 
    210                 215                 220                 


Asn Arg Asp Gly Lys Met Asp Lys Glu Glu Thr Lys Asp Trp Ile Leu 
225                 230                 235                 240 


Pro Ser Asp Tyr Asp His Ala Glu Ala Glu Ala Arg His Leu Val Tyr 
                245                 250                 255     


Glu Ser Asp Gln Asn Lys Asp Gly Lys Leu Thr Lys Glu Glu Ile Val 
            260                 265                 270         


Asp Lys Tyr Asp Leu Phe Val Gly Ser Gln Ala Thr Asp Phe Gly Glu 
        275                 280                 285             


Ala Leu Val Arg His Asp Glu Phe 
    290                 295     


<210>  1835
<211>  328
<212>  PRT
<213>  Homo Sapiens

<400>  1835

Ser Pro Ser Gly Val Arg Leu Val Gly Gly Leu His Arg Cys Glu Gly 
1               5                   10                  15      


Arg Val Glu Val Glu Gln Lys Gly Gln Trp Gly Thr Val Cys Asp Asp 
            20                  25                  30          


Gly Trp Asp Ile Lys Asp Val Ala Val Leu Cys Arg Glu Leu Gly Cys 
        35                  40                  45              


Gly Ala Ala Ser Gly Thr Pro Ser Gly Ile Leu Tyr Glu Pro Pro Ala 
    50                  55                  60                  


Glu Lys Glu Gln Lys Val Leu Ile Gln Ser Val Ser Cys Thr Gly Thr 
65                  70                  75                  80  


Glu Asp Thr Leu Ala Gln Cys Glu Gln Glu Glu Val Tyr Asp Cys Ser 
                85                  90                  95      


His Asp Glu Asp Ala Gly Ala Ser Cys Glu Asn Pro Glu Ser Ser Phe 
            100                 105                 110         


Ser Pro Val Pro Glu Gly Val Arg Leu Ala Asp Gly Pro Gly His Cys 
        115                 120                 125             


Lys Gly Arg Val Glu Val Lys His Gln Asn Gln Trp Tyr Thr Val Cys 
    130                 135                 140                 


Gln Thr Gly Trp Ser Leu Arg Ala Ala Lys Val Val Cys Arg Gln Leu 
145                 150                 155                 160 


Gly Cys Gly Arg Ala Val Leu Thr Gln Lys Arg Cys Asn Lys His Ala 
                165                 170                 175     


Tyr Gly Arg Lys Pro Ile Trp Leu Ser Gln Met Ser Cys Ser Gly Arg 
            180                 185                 190         


Glu Ala Thr Leu Gln Asp Cys Pro Ser Gly Pro Trp Gly Lys Asn Thr 
        195                 200                 205             


Cys Asn His Asp Glu Asp Thr Trp Val Glu Cys Glu Asp Pro Phe Asp 
    210                 215                 220                 


Leu Arg Leu Val Gly Gly Asp Asn Leu Cys Ser Gly Arg Leu Glu Val 
225                 230                 235                 240 


Leu His Lys Gly Val Trp Gly Ser Val Cys Asp Asp Asn Trp Gly Glu 
                245                 250                 255     


Lys Glu Asp Gln Val Val Cys Lys Gln Leu Gly Cys Gly Lys Ser Leu 
            260                 265                 270         


Ser Pro Ser Phe Arg Asp Arg Lys Cys Tyr Gly Pro Gly Val Gly Arg 
        275                 280                 285             


Ile Trp Leu Asp Asn Val Arg Cys Ser Gly Glu Glu Gln Ser Leu Glu 
    290                 295                 300                 


Gln Cys Gln His Arg Phe Trp Gly Phe His Asp Cys Thr His Gln Glu 
305                 310                 315                 320 


Asp Val Ala Val Ile Cys Ser Gly 
                325             


<210>  1836
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  1836

Cys Ile Gly Val Leu Glu Gln Asn Asn Phe Ser Leu Asn Arg Arg Met 
1               5                   10                  15      


Gln Lys Ala Arg His Cys Gly His Cys Pro Glu Glu Trp Ile Thr Tyr 
            20                  25                  30          


Ser Asn Ser Cys Tyr Tyr Ile Gly Lys Glu Arg Arg Thr Trp Glu Glu 
        35                  40                  45              


Arg Val Cys Trp Pro Val Leu Arg Arg Thr Leu Ile Cys Phe Leu 
    50                  55                  60              


<210>  1837
<211>  316
<212>  PRT
<213>  Homo Sapiens

<400>  1837

Met Ala Thr Phe Val Glu Leu Ser Thr Lys Ala Lys Met Pro Ile Val 
1               5                   10                  15      


Gly Leu Gly Thr Trp Lys Ser Pro Leu Gly Lys Val Lys Glu Ala Val 
            20                  25                  30          


Lys Val Ala Ile Asp Ala Gly Tyr Arg His Ile Asp Cys Ala Tyr Val 
        35                  40                  45              


Tyr Gln Asn Glu His Glu Val Gly Glu Ala Ile Gln Glu Lys Ile Gln 
    50                  55                  60                  


Glu Lys Ala Val Lys Arg Glu Asp Leu Phe Ile Val Ser Lys Leu Trp 
65                  70                  75                  80  


Pro Thr Phe Phe Glu Arg Pro Leu Val Arg Lys Ala Phe Glu Lys Thr 
                85                  90                  95      


Leu Lys Asp Leu Lys Leu Ser Tyr Leu Asp Val Tyr Leu Ile His Trp 
            100                 105                 110         


Pro Gln Gly Phe Lys Ser Gly Asp Asp Leu Phe Pro Lys Asp Asp Lys 
        115                 120                 125             


Gly Asn Ala Ile Gly Gly Lys Ala Thr Phe Leu Asp Ala Trp Glu Ala 
    130                 135                 140                 


Met Glu Glu Leu Val Asp Glu Gly Leu Val Lys Ala Leu Gly Val Ser 
145                 150                 155                 160 


Asn Phe Ser His Phe Gln Ile Glu Lys Leu Leu Asn Lys Pro Gly Leu 
                165                 170                 175     


Lys Tyr Lys Pro Val Thr Asn Gln Val Glu Cys His Pro Tyr Leu Thr 
            180                 185                 190         


Gln Glu Lys Leu Ile Gln Tyr Cys His Ser Lys Gly Ile Thr Val Thr 
        195                 200                 205             


Ala Tyr Ser Pro Leu Gly Ser Pro Asp Arg Pro Trp Ala Lys Pro Glu 
    210                 215                 220                 


Asp Pro Ser Leu Leu Glu Asp Pro Lys Ile Lys Glu Ile Ala Ala Lys 
225                 230                 235                 240 


His Lys Lys Thr Ala Ala Gln Val Leu Ile Arg Phe His Ile Gln Arg 
                245                 250                 255     


Asn Val Ile Val Ile Pro Lys Ser Val Thr Pro Ala Arg Ile Val Glu 
            260                 265                 270         


Asn Ile Gln Val Phe Asp Phe Lys Leu Ser Asp Glu Glu Met Ala Thr 
        275                 280                 285             


Ile Leu Ser Phe Asn Arg Asn Trp Arg Ala Cys Asn Val Leu Gln Ser 
    290                 295                 300                 


Ser His Leu Glu Asp Tyr Pro Phe Asp Ala Glu Tyr 
305                 310                 315     


<210>  1838
<211>  377
<212>  PRT
<213>  Homo Sapiens

<400>  1838

Ala Phe Asp Gln Lys Ser Tyr Phe Tyr Arg Ser Ser Phe Gln Leu Leu 
1               5                   10                  15      


Asn Val Glu Tyr Asn Ser Gln Leu Asn Ser Pro Ala Thr Gln Glu Tyr 
            20                  25                  30          


Arg Thr Leu Ser Gly Arg Ile Glu Ser Leu Ile Thr Lys Thr Phe Lys 
        35                  40                  45              


Glu Ser Asn Leu Arg Asn Gln Phe Ile Arg Ala His Val Ala Lys Leu 
    50                  55                  60                  


Arg Gln Asp Gly Ser Gly Val Arg Ala Asp Val Val Met Lys Phe Gln 
65                  70                  75                  80  


Phe Thr Arg Asn Asn Asn Gly Ala Ser Met Lys Ser Arg Ile Glu Ser 
                85                  90                  95      


Val Leu Arg Gln Met Leu Asn Asn Ser Gly Asn Leu Glu Ile Asn Pro 
            100                 105                 110         


Ser Thr Glu Ile Thr Ser Leu Thr Asp Gln Ala Ala Ala Asn Trp Leu 
        115                 120                 125             


Ile Asn Glu Cys Gly Ala Gly Pro Asp Leu Ile Thr Leu Ser Glu Gln 
    130                 135                 140                 


Arg Ile Leu Gly Gly Thr Glu Ala Glu Glu Gly Ser Trp Pro Trp Gln 
145                 150                 155                 160 


Val Ser Leu Arg Leu Asn Asn Ala His His Cys Gly Gly Ser Leu Ile 
                165                 170                 175     


Asn Asn Met Trp Ile Leu Thr Ala Ala His Cys Phe Arg Ser Asn Ser 
            180                 185                 190         


Asn Pro Arg Asp Trp Ile Ala Thr Ser Gly Ile Ser Thr Thr Phe Pro 
        195                 200                 205             


Lys Leu Arg Met Arg Val Arg Asn Ile Leu Ile His Asn Asn Tyr Lys 
    210                 215                 220                 


Ser Ala Thr His Glu Asn Asp Ile Ala Leu Val Arg Leu Glu Asn Ser 
225                 230                 235                 240 


Val Thr Phe Thr Lys Asp Ile His Ser Val Cys Leu Pro Ala Ala Thr 
                245                 250                 255     


Gln Asn Ile Pro Pro Gly Ser Thr Ala Tyr Val Thr Gly Trp Gly Ala 
            260                 265                 270         


Gln Glu Tyr Ala Gly His Thr Val Pro Glu Leu Arg Gln Gly Gln Val 
        275                 280                 285             


Arg Ile Ile Ser Asn Asp Val Cys Asn Ala Pro His Ser Tyr Asn Gly 
    290                 295                 300                 


Ala Ile Leu Ser Gly Met Leu Cys Ala Gly Val Pro Gln Gly Gly Val 
305                 310                 315                 320 


Asp Ala Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Gln Glu Asp Ser 
                325                 330                 335     


Arg Arg Leu Trp Phe Ile Val Gly Ile Val Ser Trp Gly Asp Gln Cys 
            340                 345                 350         


Gly Leu Pro Asp Lys Pro Gly Val Tyr Thr Arg Val Thr Ala Tyr Leu 
        355                 360                 365             


Asp Trp Ile Arg Gln Gln Thr Gly Ile 
    370                 375         


<210>  1839
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  1839

Lys Lys Lys Gly Ser Gln Gly Ala Ile Pro Pro Pro Asp Lys Ala Gln 
1               5                   10                  15      


His Asn Asp Ser Glu Gln Thr Gln Ser Pro Gln Gln Pro Gly Ser Arg 
            20                  25                  30          


Asn Arg Gly Arg Gly Gln Gly Arg Gly Thr Ala Met Pro Gly Glu Glu 
        35                  40                  45              


Val Leu Glu Ser Ser Gln Glu Ala Leu His Val Thr Glu Arg Lys Tyr 
    50                  55                  60                  


Leu Lys Arg Asp Trp Cys Lys Thr Gln Pro Leu Lys Gln Thr Ile His 
65                  70                  75                  80  


Glu Glu Gly Cys Asn Ser Arg Thr Ile Ile Asn Arg Phe Cys Tyr Gly 
                85                  90                  95      


Gln Cys Asn Ser Phe Tyr Ile Pro Arg His Ile Arg Lys Glu Glu Gly 
            100                 105                 110         


Ser Phe Gln Ser Cys Ser Phe Cys Lys Pro Lys Lys Phe Thr Thr Met 
        115                 120                 125             


Met Val Thr Leu Asn Cys Pro Glu Leu Gln Pro Pro Thr Lys Lys Lys 
    130                 135                 140                 


Arg Val Thr Arg Val Lys Gln Cys Arg Cys Ile Ser Ile Asp Leu Asp 
145                 150                 155                 160 


<210>  1840
<211>  714
<212>  PRT
<213>  Homo Sapiens

<400>  1840

Ser Asp Arg Pro Arg Gly Arg Asp Pro Val Asn Pro Glu Lys Leu Leu 
1               5                   10                  15      


Val Ile Thr Val Ala Thr Ala Glu Thr Glu Gly Tyr Leu Arg Phe Leu 
            20                  25                  30          


Arg Ser Ala Glu Phe Phe Asn Tyr Thr Val Arg Thr Leu Gly Leu Gly 
        35                  40                  45              


Glu Glu Trp Arg Gly Gly Asp Val Ala Arg Thr Val Gly Gly Gly Gln 
    50                  55                  60                  


Lys Val Arg Trp Leu Lys Lys Glu Met Glu Lys Tyr Ala Asp Arg Glu 
65                  70                  75                  80  


Asp Met Ile Ile Met Phe Val Asp Ser Tyr Asp Val Ile Leu Ala Gly 
                85                  90                  95      


Ser Pro Thr Glu Leu Leu Lys Lys Phe Val Gln Ser Gly Ser Arg Leu 
            100                 105                 110         


Leu Phe Ser Ala Glu Ser Phe Cys Trp Pro Glu Trp Gly Leu Ala Glu 
        115                 120                 125             


Gln Tyr Pro Glu Val Gly Thr Gly Lys Arg Phe Leu Asn Ser Gly Gly 
    130                 135                 140                 


Phe Ile Gly Phe Ala Thr Thr Ile His Gln Ile Val Arg Gln Trp Lys 
145                 150                 155                 160 


Tyr Lys Asp Asp Asp Asp Asp Gln Leu Phe Tyr Thr Arg Leu Tyr Leu 
                165                 170                 175     


Asp Pro Gly Leu Arg Glu Lys Leu Ser Leu Asn Leu Asp His Lys Ser 
            180                 185                 190         


Arg Ile Phe Gln Asn Leu Asn Gly Ala Leu Asp Glu Val Val Leu Lys 
        195                 200                 205             


Phe Asp Arg Asn Arg Val Arg Ile Arg Asn Val Ala Tyr Asp Thr Leu 
    210                 215                 220                 


Pro Ile Val Val His Gly Asn Gly Pro Thr Lys Leu Gln Leu Asn Tyr 
225                 230                 235                 240 


Leu Gly Asn Tyr Val Pro Asn Gly Trp Thr Pro Glu Gly Gly Cys Gly 
                245                 250                 255     


Phe Cys Asn Gln Asp Arg Arg Thr Leu Pro Gly Gly Gln Pro Pro Pro 
            260                 265                 270         


Arg Val Phe Leu Ala Val Phe Val Glu Gln Pro Thr Pro Phe Leu Pro 
        275                 280                 285             


Arg Phe Leu Gln Arg Leu Leu Leu Leu Asp Tyr Pro Pro Asp Arg Val 
    290                 295                 300                 


Thr Leu Phe Leu His Asn Asn Glu Val Phe His Glu Pro His Ile Ala 
305                 310                 315                 320 


Asp Ser Trp Pro Gln Leu Gln Asp His Phe Ser Ala Val Lys Leu Val 
                325                 330                 335     


Gly Pro Glu Glu Ala Leu Ser Pro Gly Glu Ala Arg Asp Met Ala Met 
            340                 345                 350         


Asp Leu Cys Arg Gln Asp Pro Glu Cys Glu Phe Tyr Phe Ser Leu Asp 
        355                 360                 365             


Ala Asp Ala Val Leu Thr Asn Leu Gln Thr Leu Arg Ile Leu Ile Glu 
    370                 375                 380                 


Glu Asn Arg Lys Val Ile Ala Pro Met Leu Ser Arg His Gly Lys Leu 
385                 390                 395                 400 


Trp Ser Asn Phe Trp Gly Ala Leu Ser Pro Asp Glu Tyr Tyr Ala Arg 
                405                 410                 415     


Ser Glu Asp Tyr Val Glu Leu Val Gln Arg Lys Arg Val Gly Val Trp 
            420                 425                 430         


Asn Val Pro Tyr Ile Ser Gln Ala Tyr Val Ile Arg Gly Asp Thr Leu 
        435                 440                 445             


Arg Met Glu Leu Pro Gln Arg Asp Val Phe Ser Gly Ser Asp Thr Asp 
    450                 455                 460                 


Pro Asp Met Ala Phe Cys Lys Ser Phe Arg Asp Lys Gly Ile Phe Leu 
465                 470                 475                 480 


His Leu Ser Asn Gln His Glu Phe Gly Arg Leu Leu Ala Thr Ser Arg 
                485                 490                 495     


Tyr Asp Thr Glu His Leu His Pro Asp Leu Trp Gln Ile Phe Asp Asn 
            500                 505                 510         


Pro Val Asp Trp Lys Glu Gln Tyr Ile His Glu Asn Tyr Ser Arg Ala 
        515                 520                 525             


Leu Glu Gly Glu Gly Ile Val Glu Gln Pro Cys Pro Asp Val Tyr Trp 
    530                 535                 540                 


Phe Pro Leu Leu Ser Glu Gln Met Cys Asp Glu Leu Val Ala Glu Met 
545                 550                 555                 560 


Glu His Tyr Gly Gln Trp Ser Gly Gly Arg His Glu Asp Ser Arg Leu 
                565                 570                 575     


Ala Gly Gly Tyr Glu Asn Val Pro Thr Val Asp Ile His Met Lys Gln 
            580                 585                 590         


Val Gly Tyr Glu Asp Gln Trp Leu Gln Leu Leu Arg Thr Tyr Val Gly 
        595                 600                 605             


Pro Met Thr Glu Ser Leu Phe Pro Gly Tyr His Thr Lys Ala Arg Ala 
    610                 615                 620                 


Val Met Asn Phe Val Val Arg Tyr Arg Pro Asp Glu Gln Pro Ser Leu 
625                 630                 635                 640 


Arg Pro His His Asp Ser Ser Thr Phe Thr Leu Asn Val Ala Leu Asn 
                645                 650                 655     


His Lys Gly Leu Asp Tyr Glu Gly Gly Gly Cys Arg Phe Leu Arg Tyr 
            660                 665                 670         


Asp Cys Val Ile Ser Ser Pro Arg Lys Gly Trp Ala Leu Leu His Pro 
        675                 680                 685             


Gly Arg Leu Thr His Tyr His Glu Gly Leu Pro Thr Thr Trp Gly Thr 
    690                 695                 700                 


Arg Tyr Ile Met Val Ser Phe Val Asp Pro 
705                 710                 


<210>  1841
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  1841

Gly Lys Leu Pro Phe Ser Arg Met Pro Ile Cys Glu His Met Val Glu 
1               5                   10                  15      


Ser Pro Thr Cys Ser Gln Met Ser Asn Leu Val Cys Gly Thr Asp Gly 
            20                  25                  30          


Leu Thr Tyr Thr Asn Glu Cys Gln Leu Cys Leu Ala Arg Ile Lys Thr 
        35                  40                  45              


Lys Gln Asp Ile Gln Ile Met Lys Asp Gly Lys Cys 
    50                  55                  60  


<210>  1842
<211>  462
<212>  PRT
<213>  Homo Sapiens

<400>  1842

Gly Lys Leu Leu Val Val Pro Met Asp Gly Ser His Trp Phe Thr Met 
1               5                   10                  15      


Arg Ser Val Val Glu Lys Leu Ile Leu Arg Gly His Glu Val Val Val 
            20                  25                  30          


Val Met Pro Glu Val Ser Trp Gln Leu Gly Arg Ser Leu Asn Cys Thr 
        35                  40                  45              


Val Lys Thr Tyr Ser Thr Ser Tyr Thr Leu Glu Asp Leu Asp Arg Glu 
    50                  55                  60                  


Phe Lys Ala Phe Ala His Ala Gln Trp Lys Ala Gln Val Arg Ser Ile 
65                  70                  75                  80  


Tyr Ser Leu Leu Met Gly Ser Tyr Asn Asp Ile Phe Asp Leu Phe Phe 
                85                  90                  95      


Ser Asn Cys Arg Ser Leu Phe Lys Asp Lys Lys Leu Val Glu Tyr Leu 
            100                 105                 110         


Lys Glu Ser Ser Phe Asp Ala Val Phe Leu Asp Pro Phe Asp Asn Cys 
        115                 120                 125             


Gly Leu Ile Val Ala Lys Tyr Phe Ser Leu Pro Ser Val Val Phe Ala 
    130                 135                 140                 


Arg Gly Ile Leu Cys His Tyr Leu Glu Glu Gly Ala Gln Cys Pro Ala 
145                 150                 155                 160 


Pro Leu Ser Tyr Val Pro Arg Ile Leu Leu Gly Phe Ser Asp Ala Met 
                165                 170                 175     


Thr Phe Lys Glu Arg Val Arg Asn His Ile Met His Leu Glu Glu His 
            180                 185                 190         


Leu Leu Cys His Arg Phe Phe Lys Asn Ala Leu Glu Ile Ala Ser Glu 
        195                 200                 205             


Ile Leu Gln Thr Pro Val Thr Glu Tyr Asp Leu Tyr Ser His Thr Ser 
    210                 215                 220                 


Ile Trp Leu Leu Arg Thr Asp Phe Val Leu Asp Tyr Pro Lys Pro Val 
225                 230                 235                 240 


Met Pro Asn Met Ile Phe Ile Gly Gly Ile Asn Cys His Gln Gly Lys 
                245                 250                 255     


Pro Leu Pro Met Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu His 
            260                 265                 270         


Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro Glu 
        275                 280                 285             


Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile Pro Gln Thr 
    290                 295                 300                 


Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn Asn 
305                 310                 315                 320 


Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His Pro 
                325                 330                 335     


Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr Glu 
            340                 345                 350         


Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly Asp 
        355                 360                 365             


Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val Thr 
    370                 375                 380                 


Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu Lys 
385                 390                 395                 400 


Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu Ser 
                405                 410                 415     


Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val Phe 
            420                 425                 430         


Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg Pro 
        435                 440                 445             


Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460         


<210>  1843
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1843

Lys Asp Pro Lys Lys Asn Glu Thr Gly Val Leu Arg Lys Leu Lys Pro 
1               5                   10                  15      


Val Asn Ala Ser Asn Ala Asn Val Lys Gln Cys Leu Trp Phe Ala Met 
            20                  25                  30          


Gln Glu Tyr Asn Lys Glu Ser Glu Asp Lys Tyr Val Phe Leu Val Val 
        35                  40                  45              


Lys Thr Leu Gln Ala Gln Leu Gln Val Thr Asn Leu Leu Glu Tyr Leu 
    50                  55                  60                  


Ile Asp Val Glu Ile Ala Arg Ser Asp Cys Arg Lys Pro Leu Ser Thr 
65                  70                  75                  80  


Asn Glu Ile Cys Ala Ile Gln Glu Asn Ser Lys Leu Lys Arg Lys Leu 
                85                  90                  95      


Ser Cys Ser Phe Leu Val Gly Ala Leu Pro Trp Asn Gly Glu Phe Thr 
            100                 105                 110         


Val Met Glu Lys Lys Cys Glu Asp Ala 
        115                 120     


<210>  1844
<211>  151
<212>  PRT
<213>  Homo Sapiens

<400>  1844

Asn Ala Ile Gln Ala Arg Ser Ser Ser Tyr Ser Gly Glu Tyr Gly Ser 
1               5                   10                  15      


Gly Gly Gly Lys Arg Phe Ser His Ser Gly Asn Gln Leu Asp Gly Pro 
            20                  25                  30          


Ile Thr Ala Leu Arg Val Arg Val Asn Thr Tyr Tyr Ile Val Gly Leu 
        35                  40                  45              


Gln Val Arg Tyr Gly Lys Val Trp Ser Asp Tyr Val Gly Gly Arg Asn 
    50                  55                  60                  


Gly Asp Leu Glu Glu Ile Phe Leu His Pro Gly Glu Ser Val Ile Gln 
65                  70                  75                  80  


Val Ser Gly Lys Tyr Lys Trp Tyr Leu Lys Lys Leu Val Phe Val Thr 
                85                  90                  95      


Asp Lys Gly Arg Tyr Leu Ser Phe Gly Lys Asp Ser Gly Thr Ser Phe 
            100                 105                 110         


Asn Ala Val Pro Leu His Pro Asn Thr Val Leu Arg Phe Ile Ser Gly 
        115                 120                 125             


Arg Ser Gly Ser Leu Ile Asp Ala Ile Gly Leu His Trp Asp Val Tyr 
    130                 135                 140                 


Pro Thr Ser Cys Ser Arg Cys 
145                 150     


<210>  1845
<211>  376
<212>  PRT
<213>  Homo Sapiens

<400>  1845

Tyr Arg Leu Phe Pro Gly Glu Pro Lys Trp Lys Lys Asn Thr Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Ser Lys Tyr Thr Pro Ser Met Ser Ser Val Glu Val Asp 
            20                  25                  30          


Lys Ala Val Glu Met Ala Leu Gln Ala Trp Ser Ser Ala Val Pro Leu 
        35                  40                  45              


Ser Phe Val Arg Ile Asn Ser Gly Glu Ala Asp Ile Met Ile Ser Phe 
    50                  55                  60                  


Glu Asn Gly Asp His Gly Asp Ser Tyr Pro Phe Asp Gly Pro Arg Gly 
65                  70                  75                  80  


Thr Leu Ala His Ala Phe Ala Pro Gly Glu Gly Leu Gly Gly Asp Thr 
                85                  90                  95      


His Phe Asp Asn Ala Glu Lys Trp Thr Met Gly Thr Asn Gly Phe Asn 
            100                 105                 110         


Leu Phe Thr Val Ala Ala His Glu Phe Gly His Ala Leu Gly Leu Ala 
        115                 120                 125             


His Ser Thr Asp Pro Ser Ala Leu Met Tyr Pro Thr Tyr Lys Tyr Lys 
    130                 135                 140                 


Asn Pro Tyr Gly Phe His Leu Pro Lys Asp Asp Val Lys Gly Ile Gln 
145                 150                 155                 160 


Ala Leu Tyr Gly Pro Arg Lys Val Phe Leu Gly Lys Pro Thr Leu Pro 
                165                 170                 175     


His Ala Pro His His Lys Pro Ser Ile Pro Asp Leu Cys Asp Ser Ser 
            180                 185                 190         


Ser Ser Phe Asp Ala Val Thr Met Leu Gly Lys Glu Leu Leu Leu Phe 
        195                 200                 205             


Lys Asp Arg Ile Phe Trp Arg Arg Gln Val His Leu Arg Thr Gly Ile 
    210                 215                 220                 


Arg Pro Ser Thr Ile Thr Ser Ser Phe Pro Gln Leu Met Ser Asn Val 
225                 230                 235                 240 


Asp Ala Ala Tyr Glu Val Ala Glu Arg Gly Thr Ala Tyr Phe Phe Lys 
                245                 250                 255     


Gly Pro His Tyr Trp Ile Thr Arg Gly Phe Gln Met Gln Gly Pro Pro 
            260                 265                 270         


Arg Thr Ile Tyr Asp Phe Gly Phe Pro Arg His Val Gln Gln Ile Asp 
        275                 280                 285             


Ala Ala Val Tyr Leu Arg Glu Pro Gln Lys Thr Leu Phe Phe Val Gly 
    290                 295                 300                 


Asp Glu Tyr Tyr Ser Tyr Asp Glu Arg Lys Arg Lys Met Glu Lys Asp 
305                 310                 315                 320 


Tyr Pro Lys Asn Thr Glu Glu Glu Phe Ser Gly Val Asn Gly Gln Ile 
                325                 330                 335     


Asp Ala Ala Val Glu Leu Asn Gly Tyr Ile Tyr Phe Phe Ser Gly Pro 
            340                 345                 350         


Lys Thr Tyr Lys Tyr Asp Thr Glu Lys Glu Asp Val Val Ser Val Val 
        355                 360                 365             


Lys Ser Ser Ser Trp Ile Gly Cys 
    370                 375     


<210>  1846
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  1846

Cys Gln Glu Ala Asn Tyr Gly Ala Leu Leu Arg Glu Leu Cys Leu Thr 
1               5                   10                  15      


Gln Phe Gln Val Asp Met Glu Ala Val Gly Glu Thr Leu Trp Cys Asp 
            20                  25                  30          


Trp Gly Arg Thr Ile Arg Ser Tyr Arg Glu Leu Ala Asp Cys Thr Trp 
        35                  40                  45              


His Met Ala Glu Lys Leu Gly Cys Phe Trp Pro Asn Ala Glu Val Asp 
    50                  55                  60                  


Arg Phe Phe Leu Ala Val His Gly Arg Tyr Phe Arg Ser Cys Pro Ile 
65                  70                  75                  80  


Ser Gly Arg Ala Val Arg Asp Pro Pro Gly Ser 
                85                  90      


<210>  1847
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  1847

Gln Pro Leu Pro Thr Thr Gly Thr Pro Gly Ser Glu Gly Gly Thr Val 
1               5                   10                  15      


Lys Asn Tyr Glu Thr Ala Val Gln Phe Cys Trp Asn His Tyr Lys Asp 
            20                  25                  30          


Gln Met Asp Pro Ile Glu Lys Asp Trp Cys Asp Trp Ala Met Ile Ser 
        35                  40                  45              


Arg Pro Tyr Ser Thr Leu Arg Asp Cys Leu Glu His Phe Ala Glu Leu 
    50                  55                  60                  


Phe Asp Leu Gly Phe Pro Asn Pro Leu Ala Glu Arg Ile Ile Phe Glu 
65                  70                  75                  80  


Thr His Gln Ile His Phe Ala Asn Cys Ser Leu Val Gln Pro Thr Phe 
                85                  90                  95      


Ser Asp Pro Pro Glu Asp Val 
            100             


<210>  1848
<211>  95
<212>  PRT
<213>  Homo Sapiens

<400>  1848

Arg Ala Gly Gly Cys Asn Glu Thr Gly Met Leu Glu Arg Leu Pro Leu 
1               5                   10                  15      


Cys Gly Lys Ala Phe Ala Asp Met Met Gly Lys Val Asp Val Trp Lys 
            20                  25                  30          


Trp Cys Asn Leu Ser Glu Phe Ile Val Tyr Tyr Glu Ser Phe Thr Asn 
        35                  40                  45              


Cys Thr Glu Met Glu Ala Asn Val Val Gly Cys Tyr Trp Pro Asn Pro 
    50                  55                  60                  


Leu Ala Gln Gly Phe Ile Thr Gly Ile His Arg Gln Phe Phe Ser Asn 
65                  70                  75                  80  


Cys Thr Val Asp Arg Val His Leu Glu Asp Pro Pro Asp Glu Val 
                85                  90                  95  


<210>  1849
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  1849

Leu Pro Lys Ser Val Asp Trp Arg Lys Lys Gly Tyr Val Thr Pro Val 
1               5                   10                  15      


Lys Asn Gln Lys Gln Cys Gly Ser Cys Trp Ala Phe Ser Ala Thr Gly 
            20                  25                  30          


Ala Leu Glu Gly Gln Met Phe Arg Lys Thr Gly Lys Leu Val Ser Leu 
        35                  40                  45              


Ser Glu Gln Asn Leu Val Asp Cys Ser Arg Pro Gln Gly Asn Gln Gly 
    50                  55                  60                  


Cys Asn Gly Gly Phe Met Ala Arg Ala Phe Gln Tyr Val Lys Glu Asn 
65                  70                  75                  80  


Gly Gly Leu Asp Ser Glu Glu Ser Tyr Pro Tyr Val Ala Val Asp Glu 
                85                  90                  95      


Ile Cys Lys Tyr Arg Pro Glu Asn Ser Val Ala Asn Asp Thr Gly Phe 
            100                 105                 110         


Thr Val Val Ala Pro Gly Lys Glu Lys Ala Leu Met Lys Ala Val Ala 
        115                 120                 125             


Thr Val Gly Pro Ile Ser Val Ala Met Asp Ala Gly His Ser Ser Phe 
    130                 135                 140                 


Gln Phe Tyr Lys Ser Gly Ile Tyr Phe Glu Pro Asp Cys Ser Ser Lys 
145                 150                 155                 160 


Asn Leu Asp His Gly Val Leu Val Val Gly Tyr Gly Phe Glu Gly Ala 
                165                 170                 175     


Asn Ser Asn Asn Ser Lys Tyr Trp Leu Val Lys Asn Ser Trp Gly Pro 
            180                 185                 190         


Glu Trp Gly Ser Asn Gly Tyr Val Lys Ile Ala Lys Asp Lys Asn Asn 
        195                 200                 205             


His Cys Gly Ile Ala Thr Ala Ala Ser Tyr Pro Asn Val 
    210                 215                 220     


<210>  1850
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  1850

Gln Pro Tyr His Gly Glu Lys Gly Ile Ser Val Pro Asp His Gly Phe 
1               5                   10                  15      


Cys Gln Pro Ile Ser Ile Pro Leu Cys Thr Asp Ile Ala Tyr Asn Gln 
            20                  25                  30          


Thr Ile Leu Pro Asn Leu Leu Gly His Thr Asn Gln Glu Asp Ala Gly 
        35                  40                  45              


Leu Glu Val His Gln Phe Tyr Pro Leu Val Lys Val Gln Cys Ser Pro 
    50                  55                  60                  


Glu Leu Arg Phe Phe Leu Cys Ser Met Tyr Ala Pro Val Cys Thr Val 
65                  70                  75                  80  


Leu Asp Gln Ala Ile Pro Pro Cys Arg Ser Leu Cys Glu Arg Ala Arg 
                85                  90                  95      


Gln Gly Cys Glu Ala Leu Met Asn Lys Phe Gly Phe Gln Trp Pro Glu 
            100                 105                 110         


Arg Leu Arg Cys Glu Asn Phe Pro Val His Gly Ala Gly Glu Ile Cys 
        115                 120                 125             


Val Gly Gln Asn Thr Ser Asp Gly Ser Gly Gly Pro Gly Gly Gly Pro 
    130                 135                 140                 


Thr Ala Tyr Pro Thr Ala Pro Tyr Leu Pro Asp Leu Pro Phe Thr Ala 
145                 150                 155                 160 


Leu Pro Pro Gly Ala Ser Asp Gly Arg Gly Arg Pro Ala Phe Pro Phe 
                165                 170                 175     


Ser Cys Pro Arg Gln Leu Lys Val Pro Pro Tyr Leu Gly Tyr Arg Phe 
            180                 185                 190         


Leu Gly Glu Arg Asp Cys Gly Ala Pro Cys Glu Pro Gly Arg Ala Asn 
        195                 200                 205             


Gly Leu Met Tyr Phe Lys Glu Glu Glu Arg Arg Phe Ala Arg Leu Trp 
    210                 215                 220                 


<210>  1851
<211>  724
<212>  PRT
<213>  Homo Sapiens

<400>  1851

Gln Pro Pro His Cys Pro Ser Val Ser His Arg Ala Gln Pro Trp Pro 
1               5                   10                  15      


His Pro Gly Gln Ser Gln Leu Phe Ala Asp Leu Ser Arg Glu Glu Leu 
            20                  25                  30          


Thr Ala Val Met Arg Phe Leu Thr Gln Arg Leu Gly Pro Gly Leu Val 
        35                  40                  45              


Asp Ala Ala Gln Ala Gln Pro Ser Asp Asn Cys Ile Phe Ser Val Glu 
    50                  55                  60                  


Leu Gln Leu Pro Pro Lys Ala Ala Ala Leu Ala His Leu Asp Arg Gly 
65                  70                  75                  80  


Ser Pro Pro Pro Ala Arg Glu Ala Leu Ala Ile Val Leu Phe Gly Gly 
                85                  90                  95      


Gln Pro Gln Pro Asn Val Ser Glu Leu Val Val Gly Pro Leu Pro His 
            100                 105                 110         


Pro Ser Tyr Met Arg Asp Val Thr Val Glu Arg His Gly Gly Pro Leu 
        115                 120                 125             


Pro Tyr His Arg Arg Pro Val Leu Arg Ala Glu Phe Thr Gln Met Trp 
    130                 135                 140                 


Arg His Leu Lys Glu Val Glu Leu Pro Lys Ala Pro Ile Phe Leu Ser 
145                 150                 155                 160 


Ser Thr Phe Asn Tyr Asn Gly Ser Thr Leu Ala Ala Val His Ala Thr 
                165                 170                 175     


Pro Arg Gly Leu Arg Ser Gly Asp Arg Ala Thr Trp Met Ala Leu Tyr 
            180                 185                 190         


His Asn Ile Ser Gly Val Gly Leu Phe Leu His Pro Val Gly Leu Glu 
        195                 200                 205             


Leu Leu Leu Asp His Arg Ala Leu Asp Pro Ala His Trp Thr Val Gln 
    210                 215                 220                 


Gln Val Phe Tyr Leu Gly His Tyr Tyr Ala Asp Leu Gly Gln Leu Glu 
225                 230                 235                 240 


Arg Glu Phe Lys Ser Gly Arg Leu Glu Val Val Arg Val Pro Leu Pro 
                245                 250                 255     


Pro Pro Asn Gly Ala Ser Ser Leu Arg Ser Arg Asn Ser Pro Gly Pro 
            260                 265                 270         


Leu Pro Pro Leu Gln Phe Ser Pro Gln Gly Ser Gln Tyr Ser Val Gln 
        275                 280                 285             


Gly Asn Leu Val Val Ser Ser Leu Trp Ser Phe Thr Phe Gly His Gly 
    290                 295                 300                 


Val Phe Ser Gly Leu Arg Ile Phe Asp Val Arg Phe Gln Gly Glu Arg 
305                 310                 315                 320 


Ile Ala Tyr Glu Val Ser Val Gln Glu Cys Val Ser Ile Tyr Gly Ala 
                325                 330                 335     


Asp Ser Pro Lys Thr Met Leu Thr Arg Tyr Leu Asp Ser Ser Phe Gly 
            340                 345                 350         


Leu Gly Arg Asn Ser Arg Gly Leu Val Arg Gly Val Asp Cys Pro Tyr 
        355                 360                 365             


Gln Ala Thr Met Val Asp Ile His Ile Leu Val Gly Lys Gly Ala Val 
    370                 375                 380                 


Gln Leu Leu Pro Gly Ala Val Cys Val Phe Glu Glu Ala Gln Gly Leu 
385                 390                 395                 400 


Pro Leu Arg Arg His His Asn Tyr Leu Gln Asn His Phe Tyr Gly Gly 
                405                 410                 415     


Leu Ala Ser Ser Ala Leu Val Val Arg Ser Val Ser Ser Val Gly Asn 
            420                 425                 430         


Tyr Asp Tyr Ile Trp Asp Phe Val Leu Tyr Pro Asn Gly Ala Leu Glu 
        435                 440                 445             


Gly Arg Val His Ala Thr Gly Tyr Ile Asn Thr Ala Phe Leu Lys Gly 
    450                 455                 460                 


Gly Glu Glu Gly Leu Leu Phe Gly Asn Arg Val Gly Glu Arg Val Leu 
465                 470                 475                 480 


Gly Thr Val His Thr His Ala Phe His Phe Lys Leu Asp Leu Asp Val 
                485                 490                 495     


Ala Gly Leu Lys Asn Trp Val Val Ala Glu Asp Val Val Phe Lys Pro 
            500                 505                 510         


Val Ala Ala Pro Trp Asn Pro Glu His Trp Leu Gln Arg Pro Gln Leu 
        515                 520                 525             


Thr Arg Gln Val Leu Gly Lys Glu Asp Leu Thr Ala Phe Ser Leu Gly 
    530                 535                 540                 


Ser Pro Leu Pro Arg Tyr Leu Tyr Leu Ala Ser Asn Gln Thr Asn Ala 
545                 550                 555                 560 


Trp Gly His Gln Arg Gly Tyr Arg Ile Gln Ile His Ser Pro Leu Gly 
                565                 570                 575     


Ile His Ile Pro Leu Glu Ser Asp Met Glu Arg Ala Leu Ser Trp Gly 
            580                 585                 590         


Arg Tyr Gln Leu Val Val Thr Gln Arg Lys Glu Glu Glu Ser Gln Ser 
        595                 600                 605             


Ser Ser Ile Tyr His Gln Asn Asp Ile Trp Thr Pro Thr Val Thr Phe 
    610                 615                 620                 


Ala Asp Phe Ile Asn Asn Glu Thr Leu Leu Gly Glu Asp Leu Val Ala 
625                 630                 635                 640 


Trp Val Thr Ala Ser Phe Leu His Ile Pro His Ala Glu Asp Ile Pro 
                645                 650                 655     


Asn Thr Val Thr Leu Gly Asn Arg Val Gly Phe Leu Leu Arg Pro Tyr 
            660                 665                 670         


Asn Phe Phe Asp Glu Asp Pro Ser Ile Phe Ser Pro Gly Ser Val Tyr 
        675                 680                 685             


Phe Glu Lys Gly Gln Asp Ala Gly Leu Cys Ser Ile Asn Pro Val Ala 
    690                 695                 700                 


Cys Leu Pro Asp Leu Ala Ala Cys Val Pro Asp Leu Pro Pro Phe Ser 
705                 710                 715                 720 


Tyr His Gly Phe 
                


<210>  1852
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  1852

Arg Met Ala Lys Lys Arg Val Ile Val Lys Lys Leu Pro Ile Val Glu 
1               5                   10                  15      


Thr Leu Gly Cys Cys Ser Val Leu Cys Ser Asp Lys Thr Gly Thr Leu 
            20                  25                  30          


Thr Ala Asn Glu Met Thr Val Thr Gln Leu Val Thr Ser Asp Gly Leu 
        35                  40                  45              


Arg Ala Glu Val Ser Gly Val Gly Tyr Asp Gly Gln Gly Thr Val Cys 
    50                  55                  60                  


Leu Leu Pro Ser Lys Glu Val Ile Lys Glu Phe Ser Asn Val Ser Val 
65                  70                  75                  80  


Gly Lys Leu Val Glu Ala Gly Cys Val Ala Asn Asn Ala Val Ile Arg 
                85                  90                  95      


Lys Asn Ala Val Met Gly Gln Pro Thr Glu Gly Ala Leu Met Ala Leu 
            100                 105                 110         


Ala Met Lys Met Asp Leu Ser Asp Ile Lys Asn Ser Tyr Ile Arg Lys 
        115                 120                 125             


Lys Glu Ile Pro Phe Ser Ser Glu Gln Lys Trp Met Ala Val Lys Cys 
    130                 135                 140                 


Ser Leu Lys Thr Glu Asp Gln Glu Asp Ile Tyr Phe Met Lys Gly Ala 
145                 150                 155                 160 


Leu Glu Glu Val Ile Arg Tyr Cys Thr Met Tyr Asn Asn Gly Gly Ile 
                165                 170                 175     


Pro Leu Pro Leu Thr Pro Gln Gln Arg Ser Phe Cys Leu Gln Glu Glu 
            180                 185                 190         


Lys Arg Met Gly Ser Leu Gly Leu Arg Val Leu Ala Leu Ala Ser Gly 
        195                 200                 205             


Pro Glu Leu Gly Arg Leu Thr Phe Leu Gly Leu Val Gly Ile Ile Asp 
    210                 215                 220                 


Pro Pro Arg Val Gly Val Lys Glu Ala Val Gln Val Leu Ser Glu Ser 
225                 230                 235                 240 


Gly Val Ser Val Lys Met Ile Thr Gly Asp Ala Leu Glu Thr Ala Leu 
                245                 250                 255     


Ala Ile Gly Arg Asn Ile Gly Leu Cys Asn Gly Lys Leu Gln Ala Met 
            260                 265                 270         


Ser Gly Glu Glu Val Asp Ser Val Glu Lys Gly Glu Leu Ala Asp Arg 
        275                 280                 285             


Val Gly Lys Val Ser Val Phe Phe Arg Thr Ser Pro Lys His Lys Leu 
    290                 295                 300                 


Lys Ile Ile Lys Ala Leu Gln Glu Ser Gly Ala Ile Val Ala Met Thr 
305                 310                 315                 320 


Gly Asp Gly Val Asn Asp Ala Val Ala Leu Lys Ser Ala Asp Ile Gly 
                325                 330                 335     


Ile Ala Met Gly Gln Thr Gly Thr Asp Val Ser Lys Glu Ala Ala Asn 
            340                 345                 350         


Met Ile Leu Val Asp Asp Asp Phe Ser Ala Ile Met Asn Ala Val Glu 
        355                 360                 365             


Glu Gly Lys Gly Ile Phe Tyr Asn Ile Lys Asn Phe Val Arg Phe Gln 
    370                 375                 380                 


Leu Ser Thr Ser Ile Ser Ala Leu Ser Leu Ile Thr Leu Ser 
385                 390                 395             


<210>  1853
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  1853

Ser Cys Gly Lys Val Leu Val Trp Ala Ala Glu Tyr Ser His Trp Met 
1               5                   10                  15      


Asn Met Lys Thr Ile Leu Lys Glu Leu Val Gln Arg Gly His Glu Val 
            20                  25                  30          


Thr Val Leu Ala Ser Ser Ala Ser Ile Leu Phe Asp Pro Asn Asp Ala 
        35                  40                  45              


Ser Thr Leu Lys Phe Glu Val Tyr Pro Thr Ser Leu Thr Lys Thr Glu 
    50                  55                  60                  


Phe Glu Asn Ile Ile Met Gln Gln Val Lys Arg Trp Ser Asp Ile Arg 
65                  70                  75                  80  


Lys Asp Ser Phe Trp Leu Tyr Phe Ser Gln Glu Gln Glu Ile Leu Trp 
                85                  90                  95      


Glu Leu Tyr Asp Ile Phe Arg Asn Phe Cys Lys Asp Val Val Ser Asn 
            100                 105                 110         


Lys Lys Val Met Lys Lys Leu Gln Glu Ser Arg Phe Asp Ile Val Phe 
        115                 120                 125             


Ala Asp Ala Val Phe Pro Cys Gly Glu Leu Leu Ala Ala Leu Leu Asn 
    130                 135                 140                 


Ile Arg Phe Val Tyr Ser Leu Arg Phe Thr Pro Gly Tyr Thr Ile Glu 
145                 150                 155                 160 


Arg His Ser Gly Gly Leu Ile Phe Pro Pro Ser Tyr Ile Pro Ile Val 
                165                 170                 175     


Met Ser Lys Leu Ser Asp Gln Met Thr Phe Met Glu Arg Val Lys Asn 
            180                 185                 190         


Met Ile Tyr Val Leu Tyr Phe Asp Phe Trp Phe Gln Met Ser Asp Met 
        195                 200                 205             


Lys Lys Trp Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr 
    210                 215                 220                 


Leu Phe Glu Thr Met Gly Lys Ala Asp Ile Trp Leu Met Arg Asn Ser 
225                 230                 235                 240 


Trp Ser Phe Gln Phe Pro His Pro Phe Leu Pro Asn Val Asp Phe Val 
                245                 250                 255     


Gly Gly Phe His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu 
            260                 265                 270         


Glu Phe Val Gln Ser Ser Gly Glu Asn Gly Val Val Val Phe Ser Leu 
        275                 280                 285             


Gly Ser Val Ile Ser Asn Met Thr Ala Glu Arg Ala Asn Val Ile Ala 
    290                 295                 300                 


Thr Ala Leu Ala Lys Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly 
305                 310                 315                 320 


Asn Lys Pro Asp Ala Leu Gly Leu Asn Thr Arg Leu Tyr Lys Trp Ile 
                325                 330                 335     


Pro Gln Asn Asp Leu Leu Gly His Pro Lys Thr Arg Ala Phe Ile Thr 
            340                 345                 350         


His Gly Gly Ala Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro 
        355                 360                 365             


Met Val Gly Ile Pro Leu Phe Phe Asp Gln Pro Asp Asn Ile Ala His 
    370                 375                 380                 


Met Lys Ala Lys Gly Ala Ala Val Arg Leu Asp Phe Asn Thr Met Ser 
385                 390                 395                 400 


Ser Thr Asp Leu Leu Asn Ala Leu Lys Thr Val Ile Asn Asp Pro Leu 
                405                 410                 415     


Tyr Lys Glu Asn Ile Met Lys Leu Ser Arg Ile Gln His Asp Gln Pro 
            420                 425                 430         


Val Lys Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Pro 
        435                 440                 445             


His Lys Gly Ala Lys His Leu Arg Val Ala Ala His Asp Leu Thr Trp 
    450                 455                 460                 


Phe Gln Tyr His Ser Leu Asp 
465                 470     


<210>  1854
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  1854

Ala Arg Ser Arg Ser Ala Pro Met Ser Pro Ser Asp Phe Leu Asp Lys 
1               5                   10                  15      


Leu Met Gly Arg Thr Ser Gly Tyr Asp Ala Arg Ile Arg Pro Asn Phe 
            20                  25                  30          


Lys Gly Pro Pro Val Asn Val Thr Cys Asn Ile Phe Ile Asn Ser Phe 
        35                  40                  45              


Gly Ser Ile Ala Glu Thr Thr Met Asp Tyr Arg Val Asn Ile Phe Leu 
    50                  55                  60                  


Arg Gln Lys Trp Asn Asp Pro Arg Leu Ala Tyr Ser Glu Tyr Pro Asp 
65                  70                  75                  80  


Asp Ser Leu Asp Leu Asp Pro Ser Met Leu Asp Ser Ile Trp Lys Pro 
                85                  90                  95      


Asp Leu Phe Phe Ala Asn Glu Lys Gly Ala Asn Phe His Glu Val Thr 
            100                 105                 110         


Thr Asp Asn Lys Leu Leu Arg Ile Phe Lys Asn Gly Asn Val Leu Tyr 
        115                 120                 125             


Ser Ile Arg Leu Thr Leu Thr Leu Ser Cys Pro Met Asp Leu Lys Asn 
    130                 135                 140                 


Phe Pro Met Asp Val Gln Thr Cys Ile Met Gln Leu Glu Ser Phe Gly 
145                 150                 155                 160 


Tyr Thr Met Asn Asp Leu Ile Phe Glu Trp Gln Asp Glu Ala Pro Val 
                165                 170                 175     


Gln Val Ala Glu Gly Leu Thr Leu Pro Gln Phe Leu Leu Lys Glu Glu 
            180                 185                 190         


Lys Asp Leu Arg Tyr Cys Thr Lys His Tyr Asn Thr Gly Lys Phe Thr 
        195                 200                 205             


Cys Ile Glu Val Arg Phe His Leu Glu Arg Gln Met Gly Tyr 
    210                 215                 220         


<210>  1855
<211>  404
<212>  PRT
<213>  Homo Sapiens

<400>  1855

Asn Gln Gln Thr Trp Phe Glu Gly Ile Phe Leu Ser Ser Met Cys Pro 
1               5                   10                  15      


Ile Asn Val Ser Ala Ser Thr Leu Tyr Gly Ile Met Phe Asp Ala Gly 
            20                  25                  30          


Ser Thr Gly Thr Arg Ile His Val Tyr Thr Phe Val Gln Lys Met Pro 
        35                  40                  45              


Gly Gln Leu Pro Ile Leu Glu Gly Glu Val Phe Asp Ser Val Lys Pro 
    50                  55                  60                  


Gly Leu Ser Ala Phe Val Asp Gln Pro Lys Gln Gly Ala Glu Thr Val 
65                  70                  75                  80  


Gln Gly Leu Leu Glu Val Ala Lys Asp Ser Ile Pro Arg Ser His Trp 
                85                  90                  95      


Lys Lys Thr Pro Val Val Leu Lys Ala Thr Ala Gly Leu Arg Leu Leu 
            100                 105                 110         


Pro Glu His Lys Ala Lys Ala Leu Leu Phe Glu Val Lys Glu Ile Phe 
        115                 120                 125             


Arg Lys Ser Pro Phe Leu Val Pro Lys Gly Ser Val Ser Ile Met Asp 
    130                 135                 140                 


Gly Ser Asp Glu Gly Ile Leu Ala Trp Val Thr Val Asn Phe Leu Thr 
145                 150                 155                 160 


Gly Gln Leu His Gly His Arg Gln Glu Thr Val Gly Thr Leu Asp Leu 
                165                 170                 175     


Gly Gly Ala Ser Thr Gln Ile Thr Phe Leu Pro Gln Phe Glu Lys Thr 
            180                 185                 190         


Leu Glu Gln Thr Pro Arg Gly Tyr Leu Thr Ser Phe Glu Met Phe Asn 
        195                 200                 205             


Ser Thr Tyr Lys Leu Tyr Thr His Ser Tyr Leu Gly Phe Gly Leu Lys 
    210                 215                 220                 


Ala Ala Arg Leu Ala Thr Leu Gly Ala Leu Glu Thr Glu Gly Thr Asp 
225                 230                 235                 240 


Gly His Thr Phe Arg Ser Ala Cys Leu Pro Arg Trp Leu Glu Ala Glu 
                245                 250                 255     


Trp Ile Phe Gly Gly Val Lys Tyr Gln Tyr Gly Gly Asn Gln Glu Gly 
            260                 265                 270         


Glu Val Gly Phe Glu Pro Cys Tyr Ala Glu Val Leu Arg Val Val Arg 
        275                 280                 285             


Gly Lys Leu His Gln Pro Glu Glu Val Gln Arg Gly Ser Phe Tyr Ala 
    290                 295                 300                 


Phe Ser Tyr Tyr Tyr Asp Arg Ala Val Asp Thr Asp Met Ile Asp Tyr 
305                 310                 315                 320 


Glu Lys Gly Gly Ile Leu Lys Val Glu Asp Phe Glu Arg Lys Ala Arg 
                325                 330                 335     


Glu Val Cys Asp Asn Leu Glu Asn Phe Thr Ser Gly Ser Pro Phe Leu 
            340                 345                 350         


Cys Met Asp Leu Ser Tyr Ile Thr Ala Leu Leu Lys Asp Gly Phe Gly 
        355                 360                 365             


Phe Ala Asp Ser Thr Val Leu Gln Leu Thr Lys Lys Val Asn Asn Ile 
    370                 375                 380                 


Glu Thr Gly Trp Ala Leu Gly Ala Thr Phe His Leu Leu Gln Ser Leu 
385                 390                 395                 400 


Gly Ile Ser His 
                


<210>  1856
<211>  565
<212>  PRT
<213>  Homo Sapiens

<400>  1856

Met Glu Asp Ser Asp Ser Ala Ala Lys Gln Leu Gly Leu Ala Glu Ala 
1               5                   10                  15      


Ala Ala Val Ala Ala Ala Ala Ala Val Ala Ala Ala Ala Ala Ala Ala 
            20                  25                  30          


Ala Gly Gly Glu Ala Glu Glu Pro Val Leu Ser Arg Asp Glu Asp Ser 
        35                  40                  45              


Glu Glu Asp Ala Asp Ser Glu Ala Glu Arg Glu Thr Pro Arg Val Thr 
    50                  55                  60                  


Ala Val Ala Val Met Ala Ala Glu Pro Gly His Met Asp Met Gly Ala 
65                  70                  75                  80  


Glu Ala Leu Pro Gly Pro Asp Glu Ala Ala Ala Ala Ala Ala Phe Ala 
                85                  90                  95      


Glu Val Thr Thr Val Thr Val Ala Asn Val Gly Ala Ala Ala Asp Asn 
            100                 105                 110         


Val Phe Thr Thr Ser Val Ala Asn Ala Ala Ser Ile Ser Gly His Val 
        115                 120                 125             


Leu Ser Gly Arg Thr Ala Leu Gln Ile Gly Asp Ser Leu Asn Thr Glu 
    130                 135                 140                 


Lys Ala Thr Leu Ile Val Val His Thr Asp Gly Ser Ile Val Glu Thr 
145                 150                 155                 160 


Thr Gly Leu Lys Gly Pro Ala Ala Pro Leu Thr Pro Gly Pro Gln Ser 
                165                 170                 175     


Pro Pro Thr Pro Leu Ala Pro Gly Gln Glu Lys Gly Gly Thr Lys Tyr 
            180                 185                 190         


Asn Trp Asp Pro Ser Val Tyr Asp Ser Glu Leu Pro Val Arg Cys Arg 
        195                 200                 205             


Asn Ile Ser Gly Thr Leu Tyr Lys Asn Arg Leu Gly Ser Gly Gly Arg 
    210                 215                 220                 


Gly Arg Cys Ile Lys Gln Gly Glu Asn Trp Tyr Ser Pro Thr Glu Phe 
225                 230                 235                 240 


Glu Ala Met Ala Gly Arg Ala Ser Ser Lys Asp Trp Lys Arg Ser Ile 
                245                 250                 255     


Arg Tyr Ala Gly Arg Pro Leu Gln Cys Leu Ile Gln Asp Gly Ile Leu 
            260                 265                 270         


Asn Pro His Ala Ala Ser Cys Thr Cys Ala Ala Cys Cys Asp Asp Met 
        275                 280                 285             


Thr Leu Ser Gly Pro Val Arg Leu Phe Val Pro Tyr Lys Arg Arg Lys 
    290                 295                 300                 


Lys Glu Asn Glu Leu Pro Thr Thr Pro Val Lys Lys Asp Ser Pro Lys 
305                 310                 315                 320 


Asn Ile Thr Leu Leu Pro Ala Thr Ala Ala Thr Thr Phe Thr Val Thr 
                325                 330                 335     


Pro Ser Gly Gln Ile Thr Thr Ser Gly Ala Leu Thr Phe Asp Arg Ala 
            340                 345                 350         


Ser Thr Val Glu Ala Thr Ala Val Ile Ser Glu Ser Pro Ala Gln Gly 
        355                 360                 365             


Asp Val Phe Ala Gly Ala Thr Val Gln Glu Ala Ser Val Gln Pro Pro 
    370                 375                 380                 


Cys Arg Ala Ser His Pro Glu Pro His Tyr Pro Gly Tyr Gln Asp Ser 
385                 390                 395                 400 


Cys Gln Ile Ala Pro Phe Pro Glu Ala Ala Leu Pro Thr Ser His Pro 
                405                 410                 415     


Lys Ile Val Leu Thr Ser Leu Pro Ala Leu Ala Val Pro Pro Pro Thr 
            420                 425                 430         


Pro Thr Lys Ala Ala Pro Pro Ala Leu Val Asn Gly Leu Glu Leu Ser 
        435                 440                 445             


Glu Pro Arg Ser Trp Leu Tyr Leu Glu Glu Met Val Asn Ser Leu Leu 
    450                 455                 460                 


Asn Thr Ala Gln Gln Leu Lys Thr Leu Phe Glu Gln Ala Lys His Ala 
465                 470                 475                 480 


Ser Thr Tyr Arg Glu Ala Ala Thr Asn Gln Ala Lys Ile His Ala Asp 
                485                 490                 495     


Ala Glu Arg Lys Glu Gln Ser Cys Val Asn Cys Gly Arg Glu Ala Met 
            500                 505                 510         


Ser Glu Cys Thr Gly Cys His Lys Val Asn Tyr Cys Ser Thr Phe Cys 
        515                 520                 525             


Gln Arg Lys Asp Trp Lys Asp His Gln His Ile Cys Gly Gln Ser Ala 
    530                 535                 540                 


Ala Val Thr Val Gln Ala Asp Glu Val His Val Ala Glu Ser Val Met 
545                 550                 555                 560 


Glu Lys Val Thr Val 
                565 


<210>  1857
<211>  511
<212>  PRT
<213>  Homo Sapiens

<400>  1857

Ala Leu Leu Ala Ala Glu Leu Lys Ser Lys Ser Cys Ser Glu Val Arg 
1               5                   10                  15      


Arg Leu Tyr Val Ser Lys Gly Phe Asn Lys Asn Asp Ala Pro Leu His 
            20                  25                  30          


Glu Ile Asn Gly Asp His Leu Lys Ile Cys Pro Gln Gly Ser Thr Cys 
        35                  40                  45              


Cys Ser Gln Glu Met Glu Glu Lys Tyr Ser Leu Gln Ser Lys Asp Asp 
    50                  55                  60                  


Phe Lys Ser Val Val Ser Glu Gln Cys Asn His Leu Gln Ala Val Phe 
65                  70                  75                  80  


Ala Ser Arg Tyr Lys Lys Phe Asp Glu Phe Phe Lys Glu Leu Leu Glu 
                85                  90                  95      


Asn Ala Glu Lys Ser Leu Asn Asp Met Phe Val Lys Thr Tyr Gly His 
            100                 105                 110         


Leu Tyr Met Gln Asn Ser Glu Leu Phe Lys Asp Leu Phe Val Glu Leu 
        115                 120                 125             


Lys Arg Tyr Tyr Val Val Gly Asn Val Asn Leu Glu Glu Met Leu Asn 
    130                 135                 140                 


Asp Phe Trp Ala Arg Leu Leu Glu Arg Met Phe Arg Leu Val Asn Ser 
145                 150                 155                 160 


Gln Tyr His Phe Thr Asp Glu Tyr Leu Glu Cys Val Ser Lys Tyr Thr 
                165                 170                 175     


Glu Gln Leu Lys Pro Phe Gly Asp Val Pro Arg Lys Leu Lys Leu Gln 
            180                 185                 190         


Val Thr Arg Ala Phe Val Ala Ala Arg Thr Phe Ala Gln Gly Leu Ala 
        195                 200                 205             


Val Ala Gly Asp Val Val Ser Lys Val Ser Val Val Asn Pro Thr Ala 
    210                 215                 220                 


Gln Cys Thr His Ala Leu Leu Lys Met Ile Tyr Cys Ser His Cys Arg 
225                 230                 235                 240 


Gly Leu Val Thr Val Lys Pro Cys Tyr Asn Tyr Cys Ser Asn Ile Met 
                245                 250                 255     


Arg Gly Cys Leu Ala Asn Gln Gly Asp Leu Asp Phe Glu Trp Asn Asn 
            260                 265                 270         


Phe Ile Asp Ala Met Leu Met Val Ala Glu Arg Leu Glu Gly Pro Phe 
        275                 280                 285             


Asn Ile Glu Ser Val Met Asp Pro Ile Asp Val Lys Ile Ser Asp Ala 
    290                 295                 300                 


Ile Met Asn Met Gln Asp Asn Ser Val Gln Val Ser Gln Lys Val Phe 
305                 310                 315                 320 


Gln Gly Cys Gly Pro Pro Lys Pro Leu Pro Ala Gly Arg Ile Ser Arg 
                325                 330                 335     


Ser Ile Ser Glu Ser Ala Phe Ser Ala Arg Phe Arg Pro His His Pro 
            340                 345                 350         


Glu Glu Arg Pro Thr Thr Ala Ala Gly Thr Ser Leu Asp Arg Leu Val 
        355                 360                 365             


Thr Asp Val Lys Glu Lys Leu Lys Gln Ala Lys Lys Phe Trp Ser Ser 
    370                 375                 380                 


Leu Pro Ser Asn Val Cys Asn Asp Glu Arg Met Ala Ala Gly Asn Gly 
385                 390                 395                 400 


Asn Glu Asp Asp Cys Trp Asn Gly Lys Gly Lys Ser Arg Tyr Leu Phe 
                405                 410                 415     


Ala Val Thr Gly Asn Gly Leu Ala Asn Gln Gly Asn Asn Pro Glu Val 
            420                 425                 430         


Gln Val Asp Thr Ser Lys Pro Asp Ile Leu Ile Leu Arg Gln Ile Met 
        435                 440                 445             


Ala Leu Arg Val Met Thr Ser Lys Met Lys Asn Ala Tyr Asn Gly Asn 
    450                 455                 460                 


Asp Val Asp Phe Phe Asp Ile Ser Asp Glu Ser Ser Gly Glu Gly Ser 
465                 470                 475                 480 


Gly Ser Gly Cys Glu Tyr Gln Gln Cys Pro Ser Glu Phe Asp Tyr Asn 
                485                 490                 495     


Ala Thr Asp His Ala Gly Lys Ser Ala Asn Glu Lys Ala Asp Ser 
            500                 505                 510     


<210>  1858
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  1858

His Ile Gly Pro Ala Pro Asp Pro Glu Asp Trp Trp Ser Tyr Lys Asp 
1               5                   10                  15      


Asn Leu Gln Gly Asn Phe Val Pro Gly Pro Pro Phe Trp Gly Leu Val 
            20                  25                  30          


Asn Ala Ala Trp Ser Leu Cys Ala Val Gly Lys Arg Gln Ser Pro Val 
        35                  40                  45              


Asp Val Glu Leu Lys Arg Val Leu Tyr Asp Pro Phe Leu Pro Pro Leu 
    50                  55                  60                  


Arg Leu Ser Thr Gly Gly Glu Lys Leu Arg Gly Thr Leu Tyr Asn Thr 
65                  70                  75                  80  


Gly Arg His Val Ser Phe Leu Pro Ala Pro Arg Pro Val Val Asn Val 
                85                  90                  95      


Ser Gly Gly Pro Leu Leu Tyr Ser His Arg Leu Ser Glu Leu Arg Leu 
            100                 105                 110         


Leu Phe Gly Ala Arg Asp Gly Ala Gly Ser Glu His Gln Ile Asn His 
        115                 120                 125             


Gln Gly Phe Ser Ala Glu Val Gln Leu Ile His Phe Asn Gln Glu Leu 
    130                 135                 140                 


Tyr Gly Asn Phe Ser Ala Ala Ser Arg Gly Pro Asn Gly Leu Ala Ile 
145                 150                 155                 160 


Leu Ser Leu Phe Val Asn Val Ala Ser Thr Ser Asn Pro Phe Leu Ser 
                165                 170                 175     


Arg Leu Leu Asn Arg Asp Thr Ile Thr Arg Ile Ser Tyr Lys Asn Asp 
            180                 185                 190         


Ala Tyr Phe Leu Gln Asp Leu Ser Leu Glu Leu Leu Phe Pro Glu Ser 
        195                 200                 205             


Phe Gly Phe Ile Thr Tyr Gln Gly Ser Leu Ser Thr Pro Pro Cys Ser 
    210                 215                 220                 


Glu Thr Val Thr Trp Ile Leu Ile Asp Arg Ala Leu Asn Ile Thr Ser 
225                 230                 235                 240 


Leu Gln Met His Ser Leu Arg Leu Leu Ser Gln Asn Pro Pro Ser Gln 
                245                 250                 255     


Ile Phe Gln Ser Leu Ser Gly Asn Ser Arg Pro Leu Gln Pro Leu Ala 
            260                 265                 270         


His Arg Ala Leu Arg Gly Asn Arg Asp Pro Arg His Pro Glu Arg Arg 
        275                 280                 285             


Cys Arg Gly Pro Asn Tyr Arg Leu His Val Asp Gly Val Pro His Gly 
    290                 295                 300                 


Arg 
305 


<210>  1859
<211>  317
<212>  PRT
<213>  Homo Sapiens

<400>  1859

Ser Arg Val Ser Gly Ile Pro Ser Arg Arg His Trp Pro Val Pro Tyr 
1               5                   10                  15      


Lys Arg Phe Asp Phe Arg Pro Lys Pro Asp Pro Tyr Cys Gln Ala Lys 
            20                  25                  30          


Tyr Thr Phe Cys Pro Thr Gly Ser Pro Ile Pro Val Met Glu Gly Asp 
        35                  40                  45              


Asp Asp Ile Glu Val Phe Arg Leu Gln Ala Pro Val Trp Glu Phe Lys 
    50                  55                  60                  


Tyr Gly Asp Leu Leu Gly His Leu Lys Ile Met His Asp Ala Ile Gly 
65                  70                  75                  80  


Phe Arg Ser Thr Leu Thr Gly Lys Asn Tyr Thr Met Glu Trp Tyr Glu 
                85                  90                  95      


Leu Phe Gln Leu Gly Asn Cys Thr Phe Pro His Leu Arg Pro Glu Met 
            100                 105                 110         


Asp Ala Pro Phe Trp Cys Asn Gln Gly Ala Ala Cys Phe Phe Glu Gly 
        115                 120                 125             


Ile Asp Asp Val His Trp Lys Glu Asn Gly Thr Leu Val Gln Val Ala 
    130                 135                 140                 


Thr Ile Ser Gly Asn Met Phe Asn Gln Met Ala Lys Trp Val Lys Gln 
145                 150                 155                 160 


Asp Asn Glu Thr Gly Ile Tyr Tyr Glu Thr Trp Asn Val Lys Ala Ser 
                165                 170                 175     


Pro Glu Lys Gly Ala Glu Thr Trp Phe Asp Ser Tyr Asp Cys Ser Lys 
            180                 185                 190         


Phe Val Leu Arg Thr Phe Asn Lys Leu Ala Glu Phe Gly Ala Glu Phe 
        195                 200                 205             


Lys Asn Ile Glu Thr Asn Tyr Thr Arg Ile Phe Leu Tyr Ser Gly Glu 
    210                 215                 220                 


Pro Thr Tyr Leu Gly Asn Glu Thr Ser Val Phe Gly Pro Thr Gly Asn 
225                 230                 235                 240 


Lys Thr Leu Gly Leu Ala Ile Lys Arg Phe Tyr Tyr Pro Phe Lys Pro 
                245                 250                 255     


His Leu Pro Thr Lys Glu Phe Leu Leu Ser Leu Leu Gln Ile Phe Asp 
            260                 265                 270         


Ala Val Ile Val His Lys Gln Phe Tyr Leu Phe Tyr Asn Phe Glu Tyr 
        275                 280                 285             


Trp Phe Leu Pro Met Lys Phe Pro Phe Ile Lys Ile Thr Tyr Glu Glu 
    290                 295                 300                 


Ile Pro Leu Pro Ile Arg Asn Lys Thr Leu Ser Gly Leu 
305                 310                 315         


<210>  1860
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  1860

Val Thr Thr Ser Thr Asn Asp Trp Val Val Thr Cys Gly Tyr Thr Ile 
1               5                   10                  15      


Pro Thr Cys Arg Lys Leu Asp Glu Leu Gly Ser Lys Gly Leu Trp Ala 
            20                  25                  30          


Asp Cys Val Met Ala Thr Gly Leu Tyr His Cys Lys Pro Leu Val Asp 
        35                  40                  45              


Ile Leu Ile Leu Pro Gly Tyr Val Gln Ala Cys Arg 
    50                  55                  60  


<210>  1861
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1861

Asp Ser Gly Cys Lys Leu Leu Glu Asp Met Val Glu Lys Thr Ile Asn 
1               5                   10                  15      


Ser Asp Ile Ser Ile Pro Glu Tyr Lys Glu Leu Leu Gln Glu Phe Ile 
            20                  25                  30          


Asp Ser Asp Ala Ala Ala Glu Ala Met Gly Lys Phe Lys Gln Cys Phe 
        35                  40                  45              


Leu Asn Gln Ser His Arg Thr Leu Lys Asn Phe Gly Leu Met Met His 
    50                  55                  60                  


Thr Val Tyr Asp Ser Ile Trp Cys Asn Met Lys Ser Asn 
65                  70                  75          


<210>  1862
<211>  290
<212>  PRT
<213>  Homo Sapiens

<400>  1862

Arg Phe Ser Gln Ser Phe Arg Glu Val Ala Gly Arg Phe Leu Ala Leu 
1               5                   10                  15      


Glu Ala Ser Thr His Leu Leu Val Phe Gly Met Glu Gln Arg Leu Pro 
            20                  25                  30          


Pro Asn Ser Glu Leu Val Gln Ala Val Leu Arg Leu Phe Gln Glu Pro 
        35                  40                  45              


Val Pro Lys Ala Ala Leu His Arg His Gly Arg Leu Ser Pro Arg Ser 
    50                  55                  60                  


Ala Arg Ala Arg Val Thr Val Glu Trp Leu Arg Val Arg Asp Asp Gly 
65                  70                  75                  80  


Ser Asn Arg Thr Ser Leu Ile Asp Ser Arg Leu Val Ser Val His Glu 
                85                  90                  95      


Ser Gly Trp Lys Ala Phe Asp Val Thr Glu Ala Val Asn Phe Trp Gln 
            100                 105                 110         


Gln Leu Ser Arg Pro Arg Gln Pro Leu Leu Leu Gln Val Ser Val Gln 
        115                 120                 125             


Arg Glu His Leu Gly Pro Leu Ala Ser Gly Ala His Lys Leu Val Arg 
    130                 135                 140                 


Phe Ala Ser Gln Gly Ala Pro Ala Gly Leu Gly Glu Pro Gln Leu Glu 
145                 150                 155                 160 


Leu His Thr Leu Asp Leu Gly Asp Tyr Gly Ala Gln Gly Asp Cys Asp 
                165                 170                 175     


Pro Glu Ala Pro Met Thr Glu Gly Thr Arg Cys Cys Arg Gln Glu Met 
            180                 185                 190         


Tyr Ile Asp Leu Gln Gly Met Lys Trp Ala Glu Asn Trp Val Leu Glu 
        195                 200                 205             


Pro Pro Gly Phe Leu Ala Tyr Glu Cys Val Gly Thr Cys Arg Gln Pro 
    210                 215                 220                 


Pro Glu Ala Leu Ala Phe Lys Trp Pro Phe Leu Gly Pro Arg Gln Cys 
225                 230                 235                 240 


Ile Ala Ser Glu Thr Asp Ser Leu Pro Met Ile Val Ser Ile Lys Glu 
                245                 250                 255     


Gly Gly Arg Thr Arg Pro Gln Val Val Ser Leu Pro Asn Met Arg Val 
            260                 265                 270         


Gln Lys Cys Ser Cys Ala Ser Asp Gly Ala Leu Val Pro Arg Arg Leu 
        275                 280                 285             


Gln Pro 
    290 


<210>  1863
<211>  189
<212>  PRT
<213>  Homo Sapiens

<400>  1863

Arg Gly Gly Arg Asp His Gly Asp Trp Asp Glu Ala Ser Arg Leu Pro 
1               5                   10                  15      


Pro Leu Pro Pro Arg Glu Asp Ala Ala Arg Val Ala Arg Phe Val Thr 
            20                  25                  30          


His Val Ser Asp Trp Gly Ala Leu Ala Thr Ile Ser Thr Leu Glu Ala 
        35                  40                  45              


Val Arg Gly Arg Pro Phe Ala Asp Val Leu Ser Leu Ser Asp Gly Pro 
    50                  55                  60                  


Pro Gly Ala Gly Ser Gly Val Pro Tyr Phe Tyr Leu Ser Pro Leu Gln 
65                  70                  75                  80  


Leu Ser Val Ser Asn Leu Gln Glu Asn Pro Tyr Ala Thr Leu Thr Met 
                85                  90                  95      


Thr Leu Ala Gln Thr Asn Phe Cys Lys Lys His Gly Phe Asp Pro Gln 
            100                 105                 110         


Ser Pro Leu Cys Val His Ile Met Leu Ser Gly Thr Val Thr Lys Val 
        115                 120                 125             


Asn Glu Thr Glu Met Asp Ile Ala Lys His Ser Leu Phe Ile Arg His 
    130                 135                 140                 


Pro Glu Met Lys Thr Trp Pro Ser Ser His Asn Trp Phe Phe Ala Lys 
145                 150                 155                 160 


Leu Asn Ile Thr Asn Ile Trp Val Leu Asp Tyr Phe Gly Gly Pro Lys 
                165                 170                 175     


Ile Val Thr Pro Glu Glu Tyr Tyr Asn Val Thr Val Gln 
            180                 185                 


<210>  1864
<211>  265
<212>  PRT
<213>  Homo Sapiens

<400>  1864

Gln Glu His Pro Ser Cys Pro Gly Pro Arg Glu Leu Glu Ala Ser Lys 
1               5                   10                  15      


Val Val Leu Leu Pro Ser Cys Pro Gly Ala Pro Gly Ser Pro Gly Glu 
            20                  25                  30          


Lys Gly Ala Pro Gly Pro Gln Gly Pro Pro Gly Pro Pro Gly Lys Met 
        35                  40                  45              


Gly Pro Lys Gly Glu Pro Gly Pro Arg Asn Cys Arg Glu Leu Leu Ser 
    50                  55                  60                  


Gln Gly Ala Thr Leu Ser Gly Trp Tyr His Leu Cys Leu Pro Glu Gly 
65                  70                  75                  80  


Arg Ala Leu Pro Val Phe Cys Asp Met Asp Thr Glu Gly Gly Gly Trp 
                85                  90                  95      


Leu Val Phe Gln Arg Arg Gln Asp Gly Ser Val Asp Phe Phe Arg Ser 
            100                 105                 110         


Trp Ser Ser Tyr Arg Ala Gly Phe Gly Asn Gln Glu Ser Glu Phe Trp 
        115                 120                 125             


Leu Gly Asn Glu Asn Leu His Gln Leu Thr Leu Gln Gly Asn Trp Glu 
    130                 135                 140                 


Leu Arg Val Glu Leu Glu Asp Phe Asn Gly Asn Arg Thr Phe Ala His 
145                 150                 155                 160 


Tyr Ala Thr Phe Arg Leu Leu Gly Glu Val Asp His Tyr Gln Leu Ala 
                165                 170                 175     


Leu Gly Lys Phe Ser Glu Gly Thr Ala Gly Asp Ser Leu Ser Leu His 
            180                 185                 190         


Ser Gly Arg Pro Phe Thr Thr Tyr Asp Ala Asp His Asp Ser Ser Asn 
        195                 200                 205             


Ser Asn Cys Ala Val Ile Val His Gly Ala Trp Trp Tyr Ala Ser Cys 
    210                 215                 220                 


Tyr Arg Ser Asn Leu Asn Gly Arg Tyr Ala Val Ser Glu Ala Ala Ala 
225                 230                 235                 240 


His Lys Tyr Gly Ile Asp Trp Ala Ser Gly Arg Gly Val Gly His Pro 
                245                 250                 255     


Tyr Arg Arg Val Arg Met Met Leu Arg 
            260                 265 


<210>  1865
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  1865

Met Pro Ala Asn Arg Leu Ser Cys Tyr Arg Lys Ile Leu Lys Asp His 
1               5                   10                  15      


Asn Cys His Asn Leu Pro Glu Gly Val Ala Asp Leu Thr Gln Ile Asp 
            20                  25                  30          


Val Asn Val Gln Asp His Phe Trp Asp Gly Lys Gly Cys Glu Met Ile 
        35                  40                  45              


Cys Tyr Cys Asn Phe Ser Glu Leu Leu Cys Cys Pro Lys Asp Val Phe 
    50                  55                  60                  


Phe Gly Pro Lys Ile Ser Phe Val Ile Pro Cys Asn Asn Gln 
65                  70                  75              


<210>  1866
<211>  200
<212>  PRT
<213>  Homo Sapiens

<400>  1866

Ser Pro Lys Gln Glu Lys Met Lys Met Asp Cys His Lys Asp Glu Lys 
1               5                   10                  15      


Gly Thr Ile Tyr Asp Tyr Glu Ala Ile Ala Leu Asn Lys Asn Glu Tyr 
            20                  25                  30          


Val Ser Phe Lys Gln Tyr Val Gly Lys His Ile Leu Phe Val Asn Val 
        35                  40                  45              


Ala Thr Tyr Cys Gly Leu Thr Ala Gln Tyr Pro Glu Leu Asn Ala Leu 
    50                  55                  60                  


Gln Glu Glu Leu Lys Pro Tyr Gly Leu Val Val Leu Gly Phe Pro Cys 
65                  70                  75                  80  


Asn Gln Phe Gly Lys Gln Glu Pro Gly Asp Asn Lys Glu Ile Leu Pro 
                85                  90                  95      


Gly Leu Lys Tyr Val Arg Pro Gly Gly Gly Phe Val Pro Ser Phe Gln 
            100                 105                 110         


Leu Phe Glu Lys Gly Asp Val Asn Gly Glu Lys Glu Gln Lys Val Phe 
        115                 120                 125             


Ser Phe Leu Lys His Ser Cys Pro His Pro Ser Glu Ile Leu Gly Thr 
    130                 135                 140                 


Phe Lys Ser Ile Ser Trp Asp Pro Val Lys Val His Asp Ile Arg Trp 
145                 150                 155                 160 


Asn Phe Glu Lys Phe Leu Val Gly Pro Asp Gly Ile Pro Val Met Arg 
                165                 170                 175     


Trp Ser His Arg Ala Thr Val Ser Ser Val Lys Thr Asp Ile Leu Ala 
            180                 185                 190         


Tyr Leu Lys Gln Phe Lys Thr Lys 
        195                 200 


<210>  1867
<211>  375
<212>  PRT
<213>  Homo Sapiens

<400>  1867

Gln Tyr Glu Arg Tyr Ser Phe Arg Ser Phe Pro Arg Asp Glu Leu Met 
1               5                   10                  15      


Pro Leu Glu Ser Ala Tyr Arg His Ala Leu Asp Lys Tyr Ser Gly Glu 
            20                  25                  30          


His Trp Ala Glu Ser Val Gly Tyr Leu Glu Ile Ser Leu Arg Leu His 
        35                  40                  45              


Arg Leu Leu Arg Asp Ser Glu Ala Phe Cys His Arg Asn Cys Ser Ala 
    50                  55                  60                  


Ala Pro Gln Pro Glu Pro Ala Ala Gly Leu Ala Ser Tyr Pro Glu Leu 
65                  70                  75                  80  


Arg Leu Phe Gly Gly Leu Leu Arg Arg Ala His Cys Leu Lys Arg Cys 
                85                  90                  95      


Lys Gln Gly Leu Pro Ala Phe Arg Gln Ser Gln Pro Ser Arg Asp Val 
            100                 105                 110         


Leu Ala Asp Phe Gln Arg Arg Glu Pro Tyr Lys Phe Leu Gln Phe Ala 
        115                 120                 125             


Tyr Phe Lys Ala Asn Asn Leu Pro Lys Ala Ile Ala Ala Ala His Thr 
    130                 135                 140                 


Phe Leu Leu Lys His Pro Asp Asp Glu Met Met Lys Arg Asn Met Ala 
145                 150                 155                 160 


Tyr Tyr Lys Ser Leu Pro Gly Ala Glu Asp Tyr Ile Lys Asp Leu Glu 
                165                 170                 175     


Thr Lys Ser Tyr Glu Ser Leu Phe Ile Arg Ala Val Arg Ala Tyr Asn 
            180                 185                 190         


Gly Glu Asn Trp Arg Thr Ser Ile Thr Asp Met Glu Leu Ala Leu Pro 
        195                 200                 205             


Asp Phe Phe Lys Ala Phe Tyr Glu Cys Leu Ala Ala Cys Glu Gly Ser 
    210                 215                 220                 


Arg Glu Ile Lys Asp Phe Lys Asp Phe Tyr Leu Ser Ile Ala Asp His 
225                 230                 235                 240 


Tyr Val Glu Val Leu Glu Cys Lys Ile Gln Cys Glu Glu Asn Leu Thr 
                245                 250                 255     


Pro Val Ile Gly Gly Tyr Pro Val Glu Lys Phe Val Ala Thr Met Tyr 
            260                 265                 270         


His Tyr Leu Gln Phe Ala Tyr Tyr Lys Leu Asn Asp Leu Lys Asn Ala 
        275                 280                 285             


Ala Pro Cys Ala Val Ser Tyr Leu Leu Phe Asp Gln Asn Asp Lys Val 
    290                 295                 300                 


Met Gln Gln Asn Leu Val Tyr Tyr Gln Tyr His Arg Asp Thr Trp Gly 
305                 310                 315                 320 


Leu Ser Asp Glu His Phe Gln Pro Arg Pro Glu Ala Val Gln Phe Phe 
                325                 330                 335     


Asn Val Thr Thr Leu Gln Lys Glu Leu Tyr Asp Phe Ala Lys Glu Asn 
            340                 345                 350         


Ile Met Asp Asp Asp Glu Gly Glu Val Val Glu Tyr Val Asp Asp Leu 
        355                 360                 365             


Leu Glu Leu Glu Glu Thr Ser 
    370                 375 


<210>  1868
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  1868

Asn Glu Phe Ser Ile Leu Lys Ser Pro Gly Ser Val Val Phe Arg Asn 
1               5                   10                  15      


Gly Asn Trp Pro Ile Pro Gly Glu Arg Ile Pro Asp Val Ala Ala Leu 
            20                  25                  30          


Ser Met Gly Phe Ser Val Lys Glu Asp Leu Ser Trp Pro Gly Leu Ala 
        35                  40                  45              


Val Gly Asn Leu Phe His Arg Pro Arg Ala Thr Val Met Val Met Val 
    50                  55                  60                  


Lys Gly Val Asn Lys Leu Ala Leu Pro Pro Gly Ser Val Ile Ser Tyr 
65                  70                  75                  80  


Pro Leu Glu Asn Ala Val Pro Phe Ser Leu Asp Ser Val Ala Asn Ser 
                85                  90                  95      


Ile His Ser Leu Phe Ser Glu Glu Thr Pro Val Val Leu Gln Leu Ala 
            100                 105                 110         


Pro Ser Glu Glu Arg Val Tyr Met Val Gly Lys Ala Asn Ser Val Phe 
        115                 120                 125             


Glu Asp Leu Ser Val Thr Leu Arg Gln Leu Arg Asn Arg Leu Phe Gln 
    130                 135                 140                 


Glu Asn Ser Val Leu Ser Ser Leu Pro Leu Asn Ser Leu Ser Arg Asn 
145                 150                 155                 160 


Asn Glu Val Asp Leu Leu Phe Leu Ser Glu Leu Gln Val Leu His Asp 
                165                 170                 175     


Ile Ser Ser Leu Leu Ser Arg His Lys His Leu Ala Lys Asp His Ser 
            180                 185                 190         


Pro Asp Leu Tyr Ser Leu Glu Leu Ala Gly Leu Asp Glu Ile Gly Lys 
        195                 200                 205             


Arg Tyr Gly Glu Asp Ser Glu Gln Phe Arg Asp Ala Ser Lys Ile Leu 
    210                 215                 220                 


Val Asp Ala Leu Gln Lys Phe Ala Asp Asp Met Tyr Ser Leu Tyr Gly 
225                 230                 235                 240 


Gly Asn Ala Val Val Glu Leu Val Thr Val Lys Ser Phe Asp Thr Ser 
                245                 250                 255     


Leu Ile Arg Lys Thr Arg Thr Ile Leu Glu Ala Lys Gln Ala Lys Asn 
            260                 265                 270         


Pro Ala Ser Pro Tyr Asn Leu Ala Tyr Lys Tyr Asn Phe Glu 
        275                 280                 285     


<210>  1869
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  1869

Gly Lys Val Leu Val Trp Pro Thr Glu Tyr Ser His Trp Ile Asn Met 
1               5                   10                  15      


Lys Thr Ile Leu Glu Glu Leu Val Gln Arg Gly His Glu Val Ile Val 
            20                  25                  30          


Leu Thr Ser Ser Ala Ser Ile Leu Val Asn Ala Ser Lys Ser Ser Ala 
        35                  40                  45              


Ile Lys Leu Glu Val Tyr Pro Thr Ser Leu Thr Lys Asn Asp Leu Glu 
    50                  55                  60                  


Asp Phe Phe Met Lys Met Phe Asp Arg Trp Thr Tyr Ser Ile Ser Lys 
65                  70                  75                  80  


Asn Thr Phe Trp Ser Tyr Phe Ser Gln Leu Gln Glu Leu Cys Trp Glu 
                85                  90                  95      


Tyr Ser Asp Tyr Asn Ile Lys Leu Cys Glu Asp Ala Val Leu Asn Lys 
            100                 105                 110         


Lys Leu Met Arg Lys Leu Gln Glu Ser Lys Phe Asp Val Leu Leu Ala 
        115                 120                 125             


Asp Ala Val Asn Pro Cys Gly Glu Leu Leu Ala Glu Leu Leu Asn Ile 
    130                 135                 140                 


Pro Phe Leu Tyr Ser Leu Arg Phe Ser Val Gly Tyr Thr Val Glu Lys 
145                 150                 155                 160 


Asn Gly Gly Gly Phe Leu Phe Pro Pro Ser Tyr Val Pro Val Val Met 
                165                 170                 175     


Ser Glu Leu Ser Asp Gln Met Ile Phe Met Glu Arg Ile Lys Asn Met 
            180                 185                 190         


Ile Tyr Met Leu Tyr Phe Asp Phe Trp Phe Gln Ala Tyr Asp Leu Lys 
        195                 200                 205             


Lys Trp Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu 
    210                 215                 220                 


Phe Glu Thr Met Gly Lys Ala Glu Met Trp Leu Ile Arg Thr Tyr Trp 
225                 230                 235                 240 


Asp Phe Glu Phe Pro Arg Pro Phe Leu Pro Asn Val Asp Phe Val Gly 
                245                 250                 255     


Gly Leu His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu 
            260                 265                 270         


Phe Val Gln Ser Ser Gly Glu Asn Gly Ile Val Val Phe Ser Leu Gly 
        275                 280                 285             


Ser Met Ile Ser Asn Met Ser Glu Glu Ser Ala Asn Met Ile Ala Ser 
    290                 295                 300                 


Ala Leu Ala Gln Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Lys 
305                 310                 315                 320 


Lys Pro Asn Thr Leu Gly Ser Asn Thr Arg Leu Tyr Lys Trp Leu Pro 
                325                 330                 335     


Gln Asn Asp Leu Leu Gly His Pro Lys Thr Lys Ala Phe Ile Thr His 
            340                 345                 350         


Gly Gly Thr Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met 
        355                 360                 365             


Val Gly Ile Pro Leu Phe Ala Asp Gln His Asp Asn Ile Ala His Met 
    370                 375                 380                 


Lys Ala Lys Gly Ala Ala Leu Ser Val Asp Ile Arg Thr Met Ser Ser 
385                 390                 395                 400 


Arg Asp Leu Leu Asn Ala Leu Lys Ser Val Ile Asn Asp Pro Ile Tyr 
                405                 410                 415     


Lys Glu Asn Ile Met Lys Leu Ser Arg Ile His His Asp Gln Pro Val 
            420                 425                 430         


Lys Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His 
        435                 440                 445             


Lys Gly Ala Lys His Leu Arg Val Ala Ala His Asn Leu Thr Trp Ile 
    450                 455                 460                 


Gln Tyr His Ser Leu Asp Val 
465                 470     


<210>  1870
<211>  387
<212>  PRT
<213>  Homo Sapiens

<400>  1870

Ser Arg Cys Ser Ala Gln Lys Asn Thr Glu Phe Ala Val Asp Leu Tyr 
1               5                   10                  15      


Gln Glu Val Ser Leu Ser His Lys Asp Asn Ile Ile Phe Ser Pro Leu 
            20                  25                  30          


Gly Ile Thr Leu Val Leu Glu Met Val Gln Leu Gly Ala Lys Gly Lys 
        35                  40                  45              


Ala Gln Gln Gln Ile Arg Gln Thr Leu Lys Gln Gln Glu Thr Ser Ala 
    50                  55                  60                  


Gly Glu Glu Phe Phe Val Leu Lys Ser Phe Phe Ser Ala Ile Ser Glu 
65                  70                  75                  80  


Lys Lys Gln Glu Phe Thr Phe Asn Leu Ala Asn Ala Leu Tyr Leu Gln 
                85                  90                  95      


Glu Gly Phe Thr Val Lys Glu Gln Tyr Leu His Gly Asn Lys Glu Phe 
            100                 105                 110         


Phe Gln Ser Ala Ile Lys Leu Val Asp Phe Gln Asp Ala Lys Ala Cys 
        115                 120                 125             


Ala Glu Met Ile Ser Thr Trp Val Glu Arg Lys Thr Asp Gly Lys Ile 
    130                 135                 140                 


Lys Asp Met Phe Ser Gly Glu Glu Phe Gly Pro Leu Thr Arg Leu Val 
145                 150                 155                 160 


Leu Val Asn Ala Ile Tyr Phe Lys Gly Asp Trp Lys Gln Lys Phe Arg 
                165                 170                 175     


Lys Glu Asp Thr Gln Leu Ile Asn Phe Thr Lys Lys Asn Gly Ser Thr 
            180                 185                 190         


Val Lys Ile Pro Met Met Lys Ala Leu Leu Arg Thr Lys Tyr Gly Tyr 
        195                 200                 205             


Phe Ser Glu Ser Ser Leu Asn Tyr Gln Val Leu Glu Leu Ser Tyr Lys 
    210                 215                 220                 


Gly Asp Glu Phe Ser Leu Ile Ile Ile Leu Pro Ala Glu Gly Met Asp 
225                 230                 235                 240 


Ile Glu Glu Val Glu Lys Leu Ile Thr Ala Gln Gln Ile Leu Lys Trp 
                245                 250                 255     


Leu Ser Glu Met Gln Glu Glu Glu Val Glu Ile Ser Leu Pro Arg Phe 
            260                 265                 270         


Lys Val Glu Gln Lys Val Asp Phe Lys Asp Val Leu Tyr Ser Leu Asn 
        275                 280                 285             


Ile Thr Glu Ile Phe Ser Gly Gly Cys Asp Leu Ser Gly Ile Thr Asp 
    290                 295                 300                 


Ser Ser Glu Val Tyr Val Ser Gln Val Thr Gln Lys Val Phe Phe Glu 
305                 310                 315                 320 


Ile Asn Glu Asp Gly Ser Glu Ala Ala Thr Ser Thr Gly Ile His Ile 
                325                 330                 335     


Pro Val Ile Met Ser Leu Ala Gln Ser Gln Phe Ile Ala Asn His Pro 
            340                 345                 350         


Phe Leu Phe Ile Met Lys His Asn Pro Thr Glu Ser Ile Leu Phe Met 
        355                 360                 365             


Gly Arg Val Thr Asn Pro Asp Thr Gln Glu Ile Lys Gly Arg Asp Leu 
    370                 375                 380                 


Asp Ser Leu 
385         


<210>  1871
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  1871

Ser Leu Ile Ser Arg Cys Asp Leu Ala Gln Val Leu Gln Leu Glu Asp 
1               5                   10                  15      


Leu Asp Gly Phe Glu Gly Tyr Ser Leu Ser Asp Trp Leu Cys Leu Ala 
            20                  25                  30          


Phe Val Glu Ser Lys Phe Asn Ile Ser Lys Ile Asn Glu Asn Ala Asp 
        35                  40                  45              


Gly Ser Phe Asp Tyr Gly Leu Phe Gln Ile Asn Ser His Tyr Trp Cys 
    50                  55                  60                  


Asn Asp Tyr Lys Ser Tyr Ser Glu Asn Leu Cys His Val Asp Cys Gln 
65                  70                  75                  80  


Asp Leu Leu Asn Pro Asn Leu Leu Ala Gly Ile His Cys Ala Lys Arg 
                85                  90                  95      


Ile Val Ser Gly Ala Arg Gly Met Asn Asn Trp Val Glu Trp Arg Leu 
            100                 105                 110         


His Cys Ser Gly Arg Pro Leu Phe Tyr Trp Leu Thr Gly Cys Arg Leu 
        115                 120                 125             


Arg 
    


<210>  1872
<211>  276
<212>  PRT
<213>  Homo Sapiens

<400>  1872

Met Asp Ser Ser Arg Glu Pro Thr Leu Gly Arg Leu Asp Ala Ala Gly 
1               5                   10                  15      


Phe Trp Gln Val Trp Gln Arg Phe Asp Ala Asp Glu Lys Gly Tyr Ile 
            20                  25                  30          


Glu Glu Lys Glu Leu Asp Ala Phe Phe Leu His Met Leu Met Lys Leu 
        35                  40                  45              


Gly Thr Asp Asp Thr Val Met Lys Ala Asn Leu His Lys Val Lys Gln 
    50                  55                  60                  


Gln Phe Met Thr Thr Gln Asp Ala Ser Lys Asp Gly Arg Ile Arg Met 
65                  70                  75                  80  


Lys Glu Leu Ala Gly Met Phe Leu Ser Glu Asp Glu Asn Phe Leu Leu 
                85                  90                  95      


Leu Phe Arg Arg Glu Asn Pro Leu Asp Ser Ser Val Glu Phe Met Gln 
            100                 105                 110         


Ile Trp Arg Lys Tyr Asp Ala Asp Ser Ser Gly Phe Ile Ser Ala Ala 
        115                 120                 125             


Glu Leu Arg Asn Phe Leu Arg Asp Leu Phe Leu His His Lys Lys Ala 
    130                 135                 140                 


Ile Ser Glu Ala Lys Leu Glu Glu Tyr Thr Gly Thr Met Met Lys Ile 
145                 150                 155                 160 


Phe Asp Arg Asn Lys Asp Gly Arg Leu Asp Leu Asn Asp Leu Ala Arg 
                165                 170                 175     


Ile Leu Ala Leu Gln Glu Asn Phe Leu Leu Gln Phe Lys Met Asp Ala 
            180                 185                 190         


Cys Ser Thr Glu Glu Arg Lys Arg Asp Phe Glu Lys Ile Phe Ala Tyr 
        195                 200                 205             


Tyr Asp Val Ser Lys Thr Gly Ala Leu Glu Gly Pro Glu Val Asp Gly 
    210                 215                 220                 


Phe Val Lys Asp Met Met Glu Leu Val Gln Pro Ser Ile Ser Gly Val 
225                 230                 235                 240 


Asp Leu Asp Lys Phe Arg Glu Ile Leu Leu Arg His Cys Asp Val Asn 
                245                 250                 255     


Lys Asp Gly Lys Ile Gln Lys Ser Glu Leu Ala Leu Cys Leu Gly Leu 
            260                 265                 270         


Lys Ile Asn Pro 
        275     


<210>  1873
<211>  278
<212>  PRT
<213>  Homo Sapiens

<400>  1873

Thr Asp Ala Thr Asn Pro Pro Glu Gly Pro Gln Asp Arg Ser Ser Gln 
1               5                   10                  15      


Gln Lys Gly Arg Leu Ser Leu Gln Asn Thr Ala Glu Ile Gln His Cys 
            20                  25                  30          


Leu Val Asn Ala Gly Asp Val Gly Cys Gly Val Phe Glu Cys Phe Glu 
        35                  40                  45              


Asn Asn Ser Cys Glu Ile Arg Gly Leu His Gly Ile Cys Met Thr Phe 
    50                  55                  60                  


Leu His Asn Ala Gly Lys Phe Asp Ala Gln Gly Lys Ser Phe Ile Lys 
65                  70                  75                  80  


Asp Ala Leu Lys Cys Lys Ala His Ala Leu Arg His Arg Phe Gly Cys 
                85                  90                  95      


Ile Ser Arg Lys Cys Pro Ala Ile Arg Glu Met Val Ser Gln Leu Gln 
            100                 105                 110         


Arg Glu Cys Tyr Leu Lys His Asp Leu Cys Ala Ala Ala Gln Glu Asn 
        115                 120                 125             


Thr Arg Val Ile Val Glu Met Ile His Phe Lys Asp Leu Leu Leu His 
    130                 135                 140                 


Glu Pro Tyr Val Asp Leu Val Asn Leu Leu Leu Thr Cys Gly Glu Glu 
145                 150                 155                 160 


Val Lys Glu Ala Ile Thr His Ser Val Gln Val Gln Cys Glu Gln Asn 
                165                 170                 175     


Trp Gly Ser Leu Cys Ser Ile Leu Ser Phe Cys Thr Ser Ala Ile Gln 
            180                 185                 190         


Lys Pro Pro Thr Ala Pro Pro Glu Arg Gln Pro Gln Val Asp Arg Thr 
        195                 200                 205             


Lys Leu Ser Arg Ala His His Gly Glu Ala Gly His His Leu Pro Glu 
    210                 215                 220                 


Pro Ser Ser Arg Glu Thr Gly Arg Gly Ala Lys Gly Glu Arg Gly Ser 
225                 230                 235                 240 


Lys Ser His Pro Asn Ala His Ala Arg Gly Arg Val Gly Gly Leu Gly 
                245                 250                 255     


Ala Gln Gly Pro Ser Gly Ser Ser Glu Trp Glu Asp Glu Gln Ser Glu 
            260                 265                 270         


Tyr Ser Asp Ile Arg Arg 
        275             


<210>  1874
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  1874

Gln Leu Cys Pro Thr Pro Cys Thr Cys Pro Trp Pro Pro Pro Arg Cys 
1               5                   10                  15      


Pro Leu Gly Val Pro Leu Val Leu Asp Gly Cys Gly Cys Cys Arg Val 
            20                  25                  30          


Cys Ala Arg Arg Leu Gly Glu Pro Cys Asp Gln Leu His Val Cys Asp 
        35                  40                  45              


Ala Ser Gln Gly Leu Val Cys Gln Pro Gly Ala Gly Pro Gly Gly Arg 
    50                  55                  60                  


Gly Ala Leu Cys Leu Leu Ala Glu Asp Asp Ser Ser Cys Glu Val Asn 
65                  70                  75                  80  


Gly Arg Leu Tyr Arg Glu Gly Glu Thr Phe Gln Pro His Cys Ser Ile 
                85                  90                  95      


Arg Cys Arg Cys Glu Asp Gly Gly Phe Thr Cys Val Pro Leu Cys Ser 
            100                 105                 110         


Glu Asp Val Arg Leu Pro Ser Trp Asp Cys Pro His Pro Arg Arg Val 
        115                 120                 125             


Glu Val Leu Gly Lys Cys Cys Pro Glu Trp Val Cys Gly Gln Gly Gly 
    130                 135                 140                 


Gly Leu Gly Thr Gln Pro Leu Pro Ala Gln Gly Pro Gln Phe Ser Gly 
145                 150                 155                 160 


Leu Val Ser Ser Leu Pro Pro Gly Val Pro Cys Pro Glu Trp Ser Thr 
                165                 170                 175     


Ala Trp Gly Pro Cys Ser Thr Thr Cys Gly Leu Gly Met Ala Thr Arg 
            180                 185                 190         


Val Ser Asn Gln Asn Arg Phe Cys Arg Leu Glu Thr Gln Arg Arg Leu 
        195                 200                 205             


Cys Leu Ser Arg Pro Cys Pro Pro Ser Arg Gly Arg Ser Pro Gln Asn 
    210                 215                 220                 


Ser Ala Phe 
225         


<210>  1875
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  1875

Leu Ile Ala Thr Pro Glu His Arg Cys Arg Val Pro Asp Ala Ala Asn 
1               5                   10                  15      


Leu Ser Ser Ala Trp Arg Asn His Thr Val Pro Leu Arg Leu Arg Asp 
            20                  25                  30          


Gly Arg Glu Val Pro His Ser Cys Arg Arg Tyr Arg Leu Ala Thr Ile 
        35                  40                  45              


Ala Asn Phe Ser Ala Leu Gly Leu Glu Pro Gly Arg Asp Val Asp Leu 
    50                  55                  60                  


Gly Gln Leu Glu Gln Glu Ser Cys Pro Asp Gly Trp Glu Phe Ser Gln 
65                  70                  75                  80  


Asp Val Tyr Leu Ser Thr Ile Val Thr Glu Trp Asn Leu Val Cys Glu 
                85                  90                  95      


Asp Asp Trp Lys Ala 
            100     


<210>  1876
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  1876

Glu Ala Pro Val Gln Glu Glu Lys Leu Ser Ala Ser Thr Ser Asn Leu 
1               5                   10                  15      


Pro Cys Trp Leu Val Glu Glu Phe Val Val Ala Glu Glu Cys Ser Pro 
            20                  25                  30          


Cys Ser Asn Phe Arg Ala Lys Thr Thr Pro Glu Cys Gly Pro Thr Gly 
        35                  40                  45              


Tyr Val Glu Lys Ile Thr Cys Ser Ser Ser Lys Arg Asn Glu Phe Lys 
    50                  55                  60                  


Ser Cys Arg Ser Ala Leu Met Glu Gln Arg Leu 
65                  70                  75  


<210>  1877
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  1877

Thr Leu Asn Ser Val Leu Asn Ser Asn Ala Ile Lys Asn Leu Pro Pro 
1               5                   10                  15      


Pro Leu Gly Gly Ala Ala Gly His Pro Gly Ser Ala Val Ser Ala Ala 
            20                  25                  30          


Pro Gly Ile Leu Tyr Pro Gly Gly Asn Lys Tyr Gln Thr Ile Asp Asn 
        35                  40                  45              


Tyr Gln Pro Tyr Pro Cys Ala Glu Asp Glu Glu Cys Gly Thr Asp Glu 
    50                  55                  60                  


Tyr Cys Ala Ser Pro Thr Arg Gly Gly Asp Ala Gly Val Gln Ile Cys 
65                  70                  75                  80  


Leu Ala Cys Arg Lys Arg Arg Lys Arg Cys Met Arg His Ala Met Cys 
                85                  90                  95      


Cys Pro Gly Asn Tyr Cys Lys Asn Gly Ile Cys Val Ser Ser Asp Gln 
            100                 105                 110         


Asn His Phe Arg Gly Glu Ile Glu Glu Thr Ile Thr Glu Ser Phe Gly 
        115                 120                 125             


Asn Asp His Ser Thr Leu Asp Gly Tyr Ser Arg Arg Thr Thr Leu Ser 
    130                 135                 140                 


Ser Lys Met Tyr His Thr Lys Gly Gln Glu Gly Ser Val Cys Leu Arg 
145                 150                 155                 160 


Ser Ser Asp Cys Ala Ser Gly Leu Cys Cys Ala Arg His Phe Trp Ser 
                165                 170                 175     


Lys Ile Cys Lys Pro Val Leu Lys Glu Gly Gln Val Cys Thr Lys His 
            180                 185                 190         


Arg Arg Lys Gly Ser His Gly Leu Glu Ile Phe Gln Arg Cys Tyr Cys 
        195                 200                 205             


Gly Glu Gly Leu Ser Cys Arg Ile Gln Lys Asp His His Gln Ala Ser 
    210                 215                 220                 


Asn Ser Ser Arg Leu His Thr Cys Gln Arg His 
225                 230                 235 


<210>  1878
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  1878

Phe Phe Ile Gly Cys Ser Ser His Gln Ile Ala Gly Ile Thr His Gln 
1               5                   10                  15      


Thr Ser Ala His Pro Gly Leu Glu Leu Ser Pro Ser Cys Met Glu Ala 
            20                  25                  30          


Cys Ser Cys Pro Leu Asp Gly Phe Asn Pro Val Cys Asp Pro Ser Thr 
        35                  40                  45              


Arg Val Glu Tyr Ile Thr Pro Cys His Ala Gly Cys Ser Ser Trp Val 
    50                  55                  60                  


Val Gln Asp Ala Leu Asp Asn Ser Gln Val Phe Tyr Thr Asn Cys Ser 
65                  70                  75                  80  


Cys Val Val Glu Gly Asn Pro Val Leu Ala Gly Ser Cys Asp Ser Thr 
                85                  90                  95      


Cys Ser His Leu Val Val Pro Phe 
            100                 


<210>  1879
<211>  821
<212>  PRT
<213>  Homo Sapiens

<400>  1879

Ala Arg Val Asn Lys His Lys Pro Trp Leu Glu Pro Thr Tyr His Gly 
1               5                   10                  15      


Ile Val Thr Glu Asn Asp Asn Thr Val Leu Leu Asp Pro Pro Leu Ile 
            20                  25                  30          


Ala Leu Asp Lys Asp Ala Pro Leu Arg Phe Ala Gly Glu Ile Cys Gly 
        35                  40                  45              


Phe Lys Ile His Gly Gln Asn Val Pro Phe Asp Ala Val Val Val Asp 
    50                  55                  60                  


Lys Ser Thr Gly Glu Gly Val Ile Arg Ser Lys Glu Lys Leu Asp Cys 
65                  70                  75                  80  


Glu Leu Gln Lys Asp Tyr Ser Phe Thr Ile Gln Ala Tyr Asp Cys Gly 
                85                  90                  95      


Lys Gly Pro Asp Gly Thr Asn Val Lys Lys Ser His Lys Ala Thr Val 
            100                 105                 110         


His Ile Gln Val Asn Asp Val Asn Glu Tyr Ala Pro Val Phe Lys Glu 
        115                 120                 125             


Lys Ser Tyr Lys Ala Thr Val Ile Glu Gly Lys Gln Tyr Asp Ser Ile 
    130                 135                 140                 


Leu Arg Val Glu Ala Val Asp Ala Asp Cys Ser Pro Gln Phe Ser Gln 
145                 150                 155                 160 


Ile Cys Ser Tyr Glu Ile Ile Thr Pro Asp Val Pro Phe Thr Val Asp 
                165                 170                 175     


Lys Asp Gly Tyr Ile Lys Asn Thr Glu Lys Leu Asn Tyr Gly Lys Glu 
            180                 185                 190         


His Gln Tyr Lys Leu Thr Val Thr Ala Tyr Asp Cys Gly Lys Lys Arg 
        195                 200                 205             


Ala Thr Glu Asp Val Leu Val Lys Ile Ser Ile Lys Pro Thr Cys Thr 
    210                 215                 220                 


Pro Gly Trp Gln Gly Trp Asn Asn Arg Ile Glu Tyr Glu Pro Gly Thr 
225                 230                 235                 240 


Gly Ala Leu Ala Val Phe Pro Asn Ile His Leu Glu Thr Cys Asp Glu 
                245                 250                 255     


Pro Val Ala Ser Val Gln Ala Thr Val Glu Leu Glu Thr Ser His Ile 
            260                 265                 270         


Gly Lys Gly Cys Asp Arg Asp Thr Tyr Ser Glu Lys Ser Leu His Arg 
        275                 280                 285             


Leu Cys Gly Ala Ala Ala Gly Thr Ala Glu Leu Leu Pro Ser Pro Ser 
    290                 295                 300                 


Gly Ser Leu Asn Trp Thr Met Gly Leu Pro Thr Asp Asn Gly His Asp 
305                 310                 315                 320 


Ser Asp Gln Val Phe Glu Phe Asn Gly Thr Gln Ala Val Arg Ile Pro 
                325                 330                 335     


Asp Gly Val Val Ser Val Ser Pro Lys Glu Pro Phe Thr Ile Ser Val 
            340                 345                 350         


Trp Met Arg His Gly Pro Phe Gly Arg Lys Lys Glu Thr Ile Leu Cys 
        355                 360                 365             


Ser Ser Asp Lys Thr Asp Met Asn Arg His His Tyr Ser Leu Tyr Val 
    370                 375                 380                 


His Gly Cys Arg Leu Ile Phe Leu Phe Arg Gln Asp Pro Ser Glu Glu 
385                 390                 395                 400 


Lys Lys Tyr Arg Pro Ala Glu Phe His Trp Lys Leu Asn Gln Val Cys 
                405                 410                 415     


Asp Glu Glu Trp His His Tyr Val Leu Asn Val Glu Phe Pro Ser Val 
            420                 425                 430         


Thr Leu Tyr Ala Asp Gly Thr Ser His Glu Pro Phe Ser Val Thr Glu 
        435                 440                 445             


Asp Tyr Pro Leu His Pro Ser Lys Ile Glu Thr Gln Leu Val Val Gly 
    450                 455                 460                 


Ala Cys Trp Gln Glu Phe Ser Gly Val Glu Asn Asp Asn Glu Thr Glu 
465                 470                 475                 480 


Pro Val Thr Val Ala Cys Ala Gly Gly Asp Leu His Met Thr Gln Phe 
                485                 490                 495     


Phe Arg Gly Asn Leu Ala Gly Leu Thr Leu Arg Ser Gly Lys Leu Ala 
            500                 505                 510         


Asp Lys Lys Val Ile Asp Cys Leu Tyr Thr Cys Lys Glu Gly Leu Asp 
        515                 520                 525             


Leu Gln Val Leu Glu Asp Ser Gly Arg Gly Val Gln Ile Gln Ala His 
    530                 535                 540                 


Arg Ser Gln Leu Val Leu Thr Leu Glu Gly Glu Asp Leu Gly Glu Leu 
545                 550                 555                 560 


Asp Lys Ala Met Gln His Ile Ser Tyr Leu Asn Ser Arg Gln Phe Pro 
                565                 570                 575     


Thr Pro Gly Ile Arg Arg Leu Lys Ile Thr Ser Thr Ile Lys Cys Phe 
            580                 585                 590         


Asn Glu Ala Thr Cys Ile Ser Val Pro Pro Val Asp Gly Tyr Val Met 
        595                 600                 605             


Val Leu Gln Pro Glu Glu Pro Lys Ile Ser Leu Ser Gly Val His His 
    610                 615                 620                 


Phe Ala Arg Ala Ala Ser Glu Phe Glu Ser Ser Glu Gly Val Phe Leu 
625                 630                 635                 640 


Phe Pro Glu Leu Arg Ile Ile Ser Thr Ile Thr Arg Glu Val Glu Pro 
                645                 650                 655     


Glu Gly Asp Gly Ala Glu Asp Pro Thr Val Gln Glu Ser Leu Val Ser 
            660                 665                 670         


Glu Glu Ile Val His Asp Leu Asp Thr Cys Glu Val Thr Val Glu Gly 
        675                 680                 685             


Glu Glu Leu Asn His Glu Gln Glu Ser Leu Glu Val Asp Met Ala Arg 
    690                 695                 700                 


Leu Gln Gln Lys Gly Ile Glu Val Ser Ser Ser Glu Leu Gly Met Thr 
705                 710                 715                 720 


Phe Thr Gly Val Asp Thr Met Ala Ser Tyr Glu Glu Val Leu His Leu 
                725                 730                 735     


Leu Arg Tyr Arg Asn Trp His Ala Arg Ser Leu Leu Asp Arg Lys Phe 
            740                 745                 750         


Lys Leu Ile Cys Ser Glu Leu Asn Gly Arg Tyr Ile Ser Asn Glu Phe 
        755                 760                 765             


Lys Val Glu Val Asn Val Ile His Thr Ala Asn Pro Met Glu His Ala 
    770                 775                 780                 


Asn His Met Ala Ala Gln Pro Gln Phe Val His Pro Glu His Arg Ser 
785                 790                 795                 800 


Phe Val Asp Leu Ser Gly His Asn Leu Ala Asn Pro His Pro Phe Ala 
                805                 810                 815     


Val Val His Ser Thr 
            820     


<210>  1880
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  1880

Lys Glu Val Val His Ala Thr Glu Gly Leu Asp Trp Glu Asp Lys Asp 
1               5                   10                  15      


Ala Pro Gly Thr Leu Val Gly Asn Val Val His Ser Arg Ile Ile Ser 
            20                  25                  30          


Pro Leu Arg Leu Phe Val Lys Gln Ser Pro Val Pro Lys Pro Gly Pro 
        35                  40                  45              


Met Ala Tyr Ala Asp Ser Met Glu Asn Phe Trp Asp Trp Leu Ala Asn 
    50                  55                  60                  


Ile Thr Glu Ile Gln Glu Pro Leu Ala Arg Thr Lys Arg Arg Pro Ile 
65                  70                  75                  80  


Val Lys Thr Gly Lys Phe Lys Lys Met Phe Gly Trp Gly Asp Phe His 
                85                  90                  95      


Ser Asn Ile Lys Thr Val Lys Leu Asn Leu Leu Ile Thr Gly Lys Ile 
            100                 105                 110         


Val Asp His Gly Asn Gly Thr Phe Arg Val Tyr Phe Arg His Asn Ser 
        115                 120                 125             


Thr Gly Leu Gly Asn Val Ser Val Ser Leu Val Pro Pro Ser Lys Val 
    130                 135                 140                 


Val Glu Phe Glu Val Ser Pro Gln Ser Thr Leu Glu Thr Lys Glu Ser 
145                 150                 155                 160 


Lys Ser Phe Asn Cys Arg Ile Glu Tyr Glu Lys Thr Asp Arg Ala Lys 
                165                 170                 175     


Lys Thr Ala Leu Cys Asn Phe Asp Pro Ser Lys Ile Cys Tyr Gln Glu 
            180                 185                 190         


Gln Thr Gln Ser His Val Ser Trp Leu Cys Ser Lys Pro Phe Lys Val 
        195                 200                 205             


Ile Cys Ile Tyr Ile Ala Phe Tyr Ser Val Asp Tyr Lys Leu Val Gln 
    210                 215                 220                 


Lys Val Cys Pro Asp Tyr Asn Tyr His Ser Glu Thr Pro Tyr Leu Ser 
225                 230                 235                 240 


Ser Gly 
        


<210>  1881
<211>  230
<212>  PRT
<213>  Homo Sapiens

<400>  1881

Gln Asp Asp Gly Pro Pro Gly Ser Glu Asp Pro Glu Arg Asp Asp His 
1               5                   10                  15      


Glu Gly Gln Pro Arg Pro Arg Val Pro Arg Lys Arg Gly His Ile Ser 
            20                  25                  30          


Pro Lys Ser Arg Pro Met Ala Asn Ser Thr Leu Leu Gly Leu Leu Ala 
        35                  40                  45              


Pro Pro Gly Glu Ala Trp Gly Ile Leu Gly Gln Pro Pro Asn Arg Pro 
    50                  55                  60                  


Asn His Ser Pro Pro Pro Ser Ala Lys Val Lys Lys Ile Phe Gly Trp 
65                  70                  75                  80  


Gly Asp Phe Tyr Ser Asn Ile Lys Thr Val Ala Leu Asn Leu Leu Val 
                85                  90                  95      


Thr Gly Lys Ile Val Asp His Gly Asn Gly Thr Phe Ser Val His Phe 
            100                 105                 110         


Gln His Asn Ala Thr Gly Gln Gly Asn Ile Ser Ile Ser Leu Val Pro 
        115                 120                 125             


Pro Ser Lys Ala Val Glu Phe His Gln Glu Gln Gln Ile Phe Ile Glu 
    130                 135                 140                 


Ala Lys Ala Ser Lys Ile Phe Asn Cys Arg Met Gly Trp Glu Lys Val 
145                 150                 155                 160 


Glu Arg Gly Arg Arg Thr Ser Leu Cys Thr His Asp Pro Ala Lys Ile 
                165                 170                 175     


Cys Ser Arg Asp His Ala Gln Ser Ser Ala Thr Trp Ser Cys Ser Gln 
            180                 185                 190         


Pro Phe Lys Val Val Cys Val Tyr Ile Ala Phe Tyr Ser Thr Asp Tyr 
        195                 200                 205             


Arg Leu Val Gln Lys Val Cys Pro Asp Tyr Asn Tyr His Ser Asp Thr 
    210                 215                 220                 


Pro Tyr Tyr Pro Ser Gly 
225                 230 


<210>  1882
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  1882

Gln Ile Pro Glu Ser Gly Arg Pro Gln Tyr Leu Gly Leu Arg Pro Ala 
1               5                   10                  15      


Ala Ala Gly Ala Gly Ala Pro Gly Gln Gln Leu Pro Glu Pro Arg Ser 
            20                  25                  30          


Ser Asp Gly Leu Gly Val Gly Arg Ala Trp Ser Trp Ala Trp Pro Thr 
        35                  40                  45              


Asn His Thr Gly Ala Leu Ala Arg Ala Gly Ala Ala Gly Ala Leu Pro 
    50                  55                  60                  


Ala Gln Arg Thr Lys Arg Lys Pro Ser Ile Lys Ala Ala Arg Ala Lys 
65                  70                  75                  80  


Lys Ile Phe Gly Trp Gly Asp Phe Tyr Phe Arg Val His Thr Leu Lys 
                85                  90                  95      


Phe Ser Leu Leu Val Thr Gly Lys Ile Val Asp His Val Asn Gly Thr 
            100                 105                 110         


Phe Ser Val Tyr Phe Arg His Asn Ser Ser Ser Leu Gly Asn Leu Ser 
        115                 120                 125             


Val Ser Ile Val Pro Pro Ser Lys Arg Val Glu Phe Gly Gly Val Trp 
    130                 135                 140                 


Leu Pro Gly Pro Val Pro His Pro Leu Gln Ser Thr Leu Ala Leu Glu 
145                 150                 155                 160 


Gly Val Leu Pro Gly Leu Gly Pro Pro Leu Gly Met Ala Ala Ala Ala 
                165                 170                 175     


Ala Gly Pro Gly Leu Gly Gly Ser Leu Gly Gly Ala Leu Ala Gly Pro 
            180                 185                 190         


Leu Gly Gly Ala Leu Gly Val Pro Gly Ala Lys Glu Ser Arg Ala Phe 
        195                 200                 205             


Asn Cys His Val Glu Tyr Glu Lys Thr Asn Arg Ala Arg Lys His Arg 
    210                 215                 220                 


Pro Cys Leu Tyr Asp Pro Ser Gln Val Cys Phe Thr Glu His Thr Gln 
225                 230                 235                 240 


Ser Gln Ala Ala Trp Leu Cys Ala Lys Pro Phe Lys Val Ile Cys Ile 
                245                 250                 255     


Phe Val Ser Phe Leu Ser Phe Asp Tyr Lys Leu Val Gln Lys Val Cys 
            260                 265                 270         


Pro Asp Tyr Asn Phe Gln Ser Glu His Pro Tyr Phe Gly 
        275                 280                 285 


<210>  1883
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  1883

Thr Asp Thr His His Pro Gln Asp Ser Ala Leu Tyr His Leu Ser Lys 
1               5                   10                  15      


Gln Leu Leu Gln Lys Tyr His Lys Glu Val Arg Pro Val Tyr Asn Trp 
            20                  25                  30          


Thr Lys Ala Thr Thr Val Tyr Leu Asp Leu Phe Val His Ala Ile Leu 
        35                  40                  45              


Asp Val Asp Ala Glu Asn Gln Ile Leu Lys Thr Ser Val Trp Tyr Gln 
    50                  55                  60                  


Glu Val Trp Asn Asp Glu Phe Leu Ser Trp Asn Ser Ser Met Phe Asp 
65                  70                  75                  80  


Glu Ile Arg Glu Ile Ser Leu Pro Leu Ser Ala Ile Trp Ala Pro Asp 
                85                  90                  95      


Ile Ile Ile Asn Glu Phe Val Asp Ile Glu Arg Tyr Pro Asp Leu Pro 
            100                 105                 110         


Tyr Val Tyr Val Asn Ser Ser Gly Thr Ile Glu Asn Tyr Lys Pro Ile 
        115                 120                 125             


Gln Val Val Ser Ala Cys Ser Leu Glu Thr Tyr Ala Phe Pro Phe Asp 
    130                 135                 140                 


Val Gln Asn Cys Ser Leu Thr Phe Lys Ser Ile Leu His Thr Val Glu 
145                 150                 155                 160 


Asp Val Asp Leu Ala Phe Leu Arg Ser Pro Glu Asp Ile Gln His Asp 
                165                 170                 175     


Lys Lys Ala Phe Leu Asn Asp Ser Glu Trp Glu Leu Leu Ser Val Ser 
            180                 185                 190         


Ser Thr Tyr Ser Ile Leu Gln Ser Ser Ala Gly Gly Phe Ala Gln Ile 
        195                 200                 205             


Gln Phe Asn Val Val Met Arg Arg His 
    210                 215         


<210>  1884
<211>  546
<212>  PRT
<213>  Homo Sapiens

<400>  1884

Ala Pro Val Ala Gly Leu Gly Ser Asp Ala Glu Leu Gln Ile Glu Arg 
1               5                   10                  15      


Arg Phe Val Pro Asp Glu Cys Pro Arg Thr Val Arg Ser Gly Asp Phe 
            20                  25                  30          


Val Arg Tyr His Tyr Val Gly Thr Phe Pro Asp Gly Gln Lys Phe Asp 
        35                  40                  45              


Ser Ser Tyr Asp Arg Asp Ser Thr Phe Asn Val Phe Val Gly Lys Gly 
    50                  55                  60                  


Gln Leu Ile Thr Gly Met Asp Gln Ala Leu Val Gly Met Cys Val Asn 
65                  70                  75                  80  


Glu Arg Arg Phe Val Lys Ile Pro Pro Lys Leu Ala Tyr Gly Asn Glu 
                85                  90                  95      


Gly Val Ser Gly Val Ile Pro Pro Asn Ser Val Leu His Phe Asp Val 
            100                 105                 110         


Leu Leu Met Asp Ile Trp Asn Ser Glu Asp Gln Val Gln Ile His Thr 
        115                 120                 125             


Tyr Phe Lys Pro Pro Ser Cys Pro Arg Thr Ile Gln Val Ser Asp Phe 
    130                 135                 140                 


Val Arg Tyr His Tyr Asn Gly Thr Phe Leu Asp Gly Thr Leu Phe Asp 
145                 150                 155                 160 


Ser Ser His Asn Arg Met Lys Thr Tyr Asp Thr Tyr Val Gly Ile Gly 
                165                 170                 175     


Trp Leu Ile Pro Gly Met Asp Lys Gly Leu Leu Gly Met Cys Val Gly 
            180                 185                 190         


Glu Lys Arg Ile Ile Thr Ile Pro Pro Phe Leu Ala Tyr Gly Glu Asp 
        195                 200                 205             


Gly Asp Gly Lys Asp Ile Pro Gly Gln Ala Ser Leu Val Phe Asp Val 
    210                 215                 220                 


Ala Leu Leu Asp Leu His Asn Pro Lys Asp Ser Ile Ser Ile Glu Asn 
225                 230                 235                 240 


Lys Val Val Pro Glu Asn Cys Glu Arg Ile Ser Gln Ser Gly Asp Phe 
                245                 250                 255     


Leu Arg Tyr His Tyr Asn Gly Thr Leu Leu Asp Gly Thr Leu Phe Asp 
            260                 265                 270         


Ser Ser Tyr Ser Arg Asn Arg Thr Phe Asp Thr Tyr Ile Gly Gln Gly 
        275                 280                 285             


Tyr Val Ile Pro Gly Met Asp Glu Gly Leu Leu Gly Val Cys Ile Gly 
    290                 295                 300                 


Glu Lys Arg Arg Ile Val Val Pro Pro His Leu Gly Tyr Gly Glu Glu 
305                 310                 315                 320 


Gly Arg Gly Asn Ile Pro Gly Ser Ala Val Leu Val Phe Asp Ile His 
                325                 330                 335     


Val Ile Asp Phe His Asn Pro Ser Asp Ser Ile Ser Ile Thr Ser His 
            340                 345                 350         


Tyr Lys Pro Pro Asp Cys Ser Val Leu Ser Lys Lys Gly Asp Tyr Leu 
        355                 360                 365             


Lys Tyr His Tyr Asn Ala Ser Leu Leu Asp Gly Thr Leu Leu Asp Ser 
    370                 375                 380                 


Thr Trp Asn Leu Gly Lys Thr Tyr Asn Ile Val Leu Gly Ser Gly Gln 
385                 390                 395                 400 


Val Val Leu Gly Met Asp Met Gly Leu Arg Glu Met Cys Val Gly Glu 
                405                 410                 415     


Lys Arg Thr Val Ile Ile Pro Pro His Leu Gly Tyr Gly Glu Ala Gly 
            420                 425                 430         


Val Asp Gly Glu Val Pro Gly Ser Ala Val Leu Val Phe Asp Ile Glu 
        435                 440                 445             


Leu Leu Glu Leu Val Ala Gly Leu Pro Glu Gly Tyr Met Phe Ile Trp 
    450                 455                 460                 


Asn Gly Glu Val Ser Pro Asn Leu Phe Glu Glu Ile Asp Lys Asp Gly 
465                 470                 475                 480 


Asn Gly Glu Val Leu Leu Glu Glu Phe Ser Glu Tyr Ile His Ala Gln 
                485                 490                 495     


Val Ala Ser Gly Lys Gly Lys Leu Ala Pro Gly Phe Asp Ala Glu Leu 
            500                 505                 510         


Ile Val Lys Asn Met Phe Thr Asn Gln Asp Arg Asn Gly Asp Gly Lys 
        515                 520                 525             


Val Thr Ala Glu Glu Phe Lys Leu Lys Asp Gln Glu Ala Lys His Asp 
    530                 535                 540                 


Glu Leu 
545     


<210>  1885
<211>  331
<212>  PRT
<213>  Homo Sapiens

<400>  1885

Thr Gly Pro Leu Asp Thr Thr Pro Glu Gly Arg Pro Gly Glu Val Ser 
1               5                   10                  15      


Asp Ala Pro Gln Arg Lys Gln Phe Cys His Trp Pro Cys Lys Cys Pro 
            20                  25                  30          


Gln Gln Lys Pro Arg Cys Pro Pro Gly Val Ser Leu Val Arg Asp Gly 
        35                  40                  45              


Cys Gly Cys Cys Lys Ile Cys Ala Lys Gln Pro Gly Glu Ile Cys Asn 
    50                  55                  60                  


Glu Ala Asp Leu Cys Asp Pro His Lys Gly Leu Tyr Cys Asp Tyr Ser 
65                  70                  75                  80  


Val Asp Arg Pro Arg Tyr Glu Thr Gly Val Cys Ala Tyr Leu Val Ala 
                85                  90                  95      


Val Gly Cys Glu Phe Asn Gln Val His Tyr His Asn Gly Gln Val Phe 
            100                 105                 110         


Gln Pro Asn Pro Leu Phe Ser Cys Leu Cys Val Ser Gly Ala Ile Gly 
        115                 120                 125             


Cys Thr Pro Leu Phe Ile Pro Lys Leu Ala Gly Ser His Cys Ser Gly 
    130                 135                 140                 


Ala Lys Gly Gly Lys Lys Ser Asp Gln Ser Asn Cys Ser Leu Glu Pro 
145                 150                 155                 160 


Leu Leu Gln Gln Leu Ser Thr Ser Tyr Lys Thr Met Pro Ala Tyr Arg 
                165                 170                 175     


Asn Leu Pro Leu Ile Trp Lys Lys Lys Cys Leu Val Gln Ala Thr Lys 
            180                 185                 190         


Trp Thr Pro Cys Ser Arg Thr Cys Gly Met Gly Ile Ser Asn Arg Val 
        195                 200                 205             


Thr Asn Glu Asn Ser Asn Cys Glu Met Arg Lys Glu Lys Arg Leu Cys 
    210                 215                 220                 


Tyr Ile Gln Pro Cys Asp Ser Asn Ile Leu Lys Thr Ile Lys Ile Pro 
225                 230                 235                 240 


Lys Gly Lys Thr Cys Gln Pro Thr Phe Gln Leu Ser Lys Ala Glu Lys 
                245                 250                 255     


Phe Val Phe Ser Gly Cys Ser Ser Thr Gln Ser Tyr Lys Pro Thr Phe 
            260                 265                 270         


Cys Gly Ile Cys Leu Asp Lys Arg Cys Cys Ile Pro Asn Lys Ser Lys 
        275                 280                 285             


Met Ile Thr Ile Gln Phe Asp Cys Pro Asn Glu Gly Ser Phe Lys Trp 
    290                 295                 300                 


Lys Met Leu Trp Ile Thr Ser Cys Val Cys Gln Arg Asn Cys Arg Glu 
305                 310                 315                 320 


Pro Gly Asp Ile Phe Ser Glu Leu Lys Ile Leu 
                325                 330     


<210>  1886
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  1886

Val Glu Val Ala Thr His Tyr Leu Glu Ile Ile Thr Gln Leu Ile Val 
1               5                   10                  15      


Glu Ser Phe His Phe Lys Asn Gly Glu Asp Ala Pro Asp Leu Leu Lys 
            20                  25                  30          


Val Ile Thr Lys Pro Phe Thr Lys Leu Ile Val Gln Leu Asp Lys Lys 
        35                  40                  45              


Val Ile Ser Gln Ile Ala Met Asn Asp Glu Lys Ala Lys Asn Lys Ser 
    50                  55                  60                  


Leu Val Lys Ile Trp Cys Lys Thr Phe Thr Asn Lys Thr Gln Ile Asn 
65                  70                  75                  80  


Val Thr Val Pro Ser Thr Ala Asn Cys Thr Ser Pro Ser Leu Cys Trp 
                85                  90                  95      


Thr Asp Gly Ile Gln Asn Trp Thr Met Lys Asn Val Thr Tyr Lys Glu 
            100                 105                 110         


Asn Ile Ala Lys Cys Gln His Ile Phe Val Asn Phe His Leu Pro Asp 
        115                 120                 125             


Leu 
    


<210>  1887
<211>  188
<212>  PRT
<213>  Homo Sapiens

<400>  1887

Met Phe His Gln Ile Trp Ala Ala Leu Leu Tyr Phe Tyr Gly Ile Ile 
1               5                   10                  15      


Leu Asn Ser Ile Tyr Gln Cys Pro Glu His Ser Gln Leu Thr Thr Leu 
            20                  25                  30          


Gly Val Asp Gly Lys Glu Phe Pro Glu Val His Leu Gly Gln Trp Tyr 
        35                  40                  45              


Phe Ile Ala Gly Ala Ala Pro Thr Lys Glu Glu Leu Ala Thr Phe Asp 
    50                  55                  60                  


Pro Val Asp Asn Ile Val Phe Asn Met Ala Ala Gly Ser Ala Pro Met 
65                  70                  75                  80  


Gln Leu His Leu Arg Ala Thr Ile Arg Met Lys Asp Gly Leu Cys Val 
                85                  90                  95      


Pro Arg Lys Trp Ile Tyr His Leu Thr Glu Gly Ser Thr Asp Leu Arg 
            100                 105                 110         


Thr Glu Gly Arg Pro Asp Met Lys Thr Glu Leu Phe Ser Ser Ser Cys 
        115                 120                 125             


Pro Gly Gly Ile Met Leu Asn Glu Thr Gly Gln Gly Tyr Gln Arg Phe 
    130                 135                 140                 


Leu Leu Tyr Asn Arg Ser Pro His Pro Pro Glu Lys Cys Val Glu Glu 
145                 150                 155                 160 


Phe Lys Ser Leu Thr Ser Cys Leu Asp Ser Lys Ala Phe Leu Leu Thr 
                165                 170                 175     


Pro Arg Asn Gln Glu Ala Cys Glu Leu Ser Asn Asn 
            180                 185             


<210>  1888
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1888

Gln Trp Gln Met Ser Ser Tyr Ala Gly Asp Asn Ile Ile Thr Ala Gln 
1               5                   10                  15      


Ala Met Tyr Lys Gly Leu Trp Met Asp Cys Val Thr Gln Ser Thr Gly 
            20                  25                  30          


Met Met Ser Cys Lys Met Tyr Asp Ser Val Leu Ala Leu Ser Ala Ala 
        35                  40                  45              


Leu Gln Ala Thr Arg 
    50              


<210>  1889
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1889

Leu Trp Lys Val Thr Ala Phe Ile Gly Asn Ser Ile Val Val Ala Gln 
1               5                   10                  15      


Val Val Trp Glu Gly Leu Trp Met Ser Cys Val Val Gln Ser Thr Gly 
            20                  25                  30          


Gln Met Gln Cys Lys Val Tyr Asp Ser Leu Leu Ala Leu Pro Gln Asp 
        35                  40                  45              


Leu Gln Ala Ala Arg 
    50              


<210>  1890
<211>  470
<212>  PRT
<213>  Homo Sapiens

<400>  1890

Gln Asp Thr Phe Thr Ala Ala Val Tyr Glu His Ala Ala Ile Leu Pro 
1               5                   10                  15      


Asn Ala Thr Leu Thr Pro Val Ser Arg Glu Glu Ala Leu Ala Leu Met 
            20                  25                  30          


Asn Arg Asn Leu Asp Ile Leu Glu Gly Ala Ile Thr Ser Ala Ala Asp 
        35                  40                  45              


Gln Gly Ala His Ile Ile Val Thr Pro Glu Asp Ala Ile Tyr Gly Trp 
    50                  55                  60                  


Asn Phe Asn Arg Asp Ser Leu Tyr Pro Tyr Leu Glu Asp Ile Pro Asp 
65                  70                  75                  80  


Pro Glu Val Asn Trp Ile Pro Cys Asn Asn Arg Asn Arg Phe Gly Gln 
                85                  90                  95      


Thr Pro Val Gln Glu Arg Leu Ser Cys Leu Ala Lys Asn Asn Ser Ile 
            100                 105                 110         


Tyr Val Val Ala Asn Ile Gly Asp Lys Lys Pro Cys Asp Thr Ser Asp 
        115                 120                 125             


Pro Gln Cys Pro Pro Asp Gly Arg Tyr Gln Tyr Asn Thr Asp Val Val 
    130                 135                 140                 


Phe Asp Ser Gln Gly Lys Leu Val Ala Arg Tyr His Lys Gln Asn Leu 
145                 150                 155                 160 


Phe Met Gly Glu Asn Gln Phe Asn Val Pro Lys Glu Pro Glu Ile Val 
                165                 170                 175     


Thr Phe Asn Thr Thr Phe Gly Ser Phe Gly Ile Phe Thr Cys Phe Asp 
            180                 185                 190         


Ile Leu Phe His Asp Pro Ala Val Thr Leu Val Lys Asp Phe His Val 
        195                 200                 205             


Asp Thr Ile Val Phe Pro Thr Ala Trp Met Asn Val Leu Pro His Leu 
    210                 215                 220                 


Ser Ala Val Glu Phe His Ser Ala Trp Ala Met Gly Met Arg Val Asn 
225                 230                 235                 240 


Phe Leu Ala Ser Asn Ile His Tyr Pro Ser Lys Lys Met Thr Gly Ser 
                245                 250                 255     


Gly Ile Tyr Ala Pro Asn Ser Ser Arg Ala Phe His Tyr Asp Met Lys 
            260                 265                 270         


Thr Glu Glu Gly Lys Leu Leu Leu Ser Gln Leu Asp Ser His Pro Ser 
        275                 280                 285             


His Ser Ala Val Val Asn Trp Thr Ser Tyr Ala Ser Ser Ile Glu Ala 
    290                 295                 300                 


Leu Ser Ser Gly Asn Lys Glu Phe Lys Gly Thr Val Phe Phe Asp Glu 
305                 310                 315                 320 


Phe Thr Phe Val Lys Leu Thr Gly Val Ala Gly Asn Tyr Thr Val Cys 
                325                 330                 335     


Gln Lys Asp Leu Cys Cys His Leu Ser Tyr Lys Met Ser Glu Asn Ile 
            340                 345                 350         


Pro Asn Glu Val Tyr Ala Leu Gly Ala Phe Asp Gly Leu His Thr Val 
        355                 360                 365             


Glu Gly Arg Tyr Tyr Leu Gln Ile Cys Thr Leu Leu Lys Cys Lys Thr 
    370                 375                 380                 


Thr Asn Leu Asn Thr Cys Gly Asp Ser Ala Glu Thr Ala Ser Thr Arg 
385                 390                 395                 400 


Phe Glu Met Phe Ser Leu Ser Gly Thr Phe Gly Thr Gln Tyr Val Phe 
                405                 410                 415     


Pro Glu Val Leu Leu Ser Glu Asn Gln Leu Ala Pro Gly Glu Phe Gln 
            420                 425                 430         


Val Ser Thr Asp Gly Arg Leu Phe Ser Leu Lys Pro Thr Ser Gly Pro 
        435                 440                 445             


Val Leu Thr Val Thr Leu Phe Gly Arg Leu Tyr Glu Lys Asp Trp Ala 
    450                 455                 460                 


Ser Asn Ala Ser Ser Gly 
465                 470 


<210>  1891
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  1891

Gln Asp Ser Phe Ile Ala Ala Val Tyr Glu His Ala Val Ile Leu Pro 
1               5                   10                  15      


Asn Lys Thr Glu Thr Pro Val Ser Gln Glu Asp Ala Leu Asn Leu Met 
            20                  25                  30          


Asn Glu Asn Ile Asp Ile Leu Glu Thr Ala Ile Lys Gln Ala Ala Glu 
        35                  40                  45              


Gln Gly Ala Arg Ile Ile Val Thr Pro Glu Asp Ala Leu Tyr Gly Trp 
    50                  55                  60                  


Lys Phe Thr Arg Glu Thr Val Phe Pro Tyr Leu Glu Asp Ile Pro Asp 
65                  70                  75                  80  


Pro Gln Val Asn Trp Ile Pro Cys Gln Asp Pro His Arg Phe Gly His 
                85                  90                  95      


Thr Pro Val Gln Ala Arg Leu Ser Cys Leu Ala Lys Asp Asn Ser Ile 
            100                 105                 110         


Tyr Val Leu Ala Asn Leu Gly Asp Lys Lys Pro Cys Asn Ser Arg Asp 
        115                 120                 125             


Ser Thr Cys Pro Pro Asn Gly Tyr Phe Gln Tyr Asn Thr Asn Val Val 
    130                 135                 140                 


Tyr Asn Thr Glu Gly Lys Leu Val Ala Arg Tyr His Lys Tyr His Leu 
145                 150                 155                 160 


Tyr Ser Glu Pro Gln Phe Asn Val Pro Glu Lys Pro Glu Leu Val Thr 
                165                 170                 175     


Phe Asn Thr Ala Phe Gly Arg Phe Gly Ile Phe Thr Cys Phe Asp Ile 
            180                 185                 190         


Phe Phe Tyr Asp Pro Gly Val Thr Leu Val Lys Asp Phe His Val Asp 
        195                 200                 205             


Thr Ile Leu Phe Pro Thr Ala Trp Met Asn Val Leu Pro Leu Leu Thr 
    210                 215                 220                 


Ala Ile Glu Phe His Ser Ala Trp Ala Met Gly Met Gly Val Asn Leu 
225                 230                 235                 240 


Leu Val Ala Asn Thr His His Val Ser Leu Asn Met Thr Gly Ser Gly 
                245                 250                 255     


Ile Tyr Ala Pro Asn Gly Pro Lys Val Tyr His Tyr Asp Met Lys Thr 
            260                 265                 270         


Glu Leu Gly Lys Leu Leu Leu Ser Glu Val Asp Ser His Pro Leu Ser 
        275                 280                 285             


Ser Leu Ala Tyr Pro Thr Ala Val Asn Trp Asn Ala Tyr Ala Thr Thr 
    290                 295                 300                 


Ile Lys Pro Phe Pro Val Gln Lys Asn Thr Phe Arg Gly Phe Ile Ser 
305                 310                 315                 320 


Arg Asp Gly Phe Asn Phe Thr Glu Leu Phe Glu Asn Ala Gly Asn Leu 
                325                 330                 335     


Thr Val Cys Gln Lys Glu Leu Cys Cys His Leu Ser Tyr Arg Met Leu 
            340                 345                 350         


Gln Lys Glu Glu Asn Glu Val Tyr Val Leu Gly Ala Phe Thr Gly Leu 
        355                 360                 365             


His Gly Arg Arg Arg Arg Glu Tyr Trp Gln Val Cys Thr Met Leu Lys 
    370                 375                 380                 


Cys Lys Thr Thr Asn Leu Thr Thr Cys Gly Arg Pro Val Glu Thr Ala 
385                 390                 395                 400 


Ser Thr Arg Phe Glu Met Phe Ser Leu Ser Gly Thr Phe Gly Thr Glu 
                405                 410                 415     


Tyr Val Phe Pro Glu Val Leu Leu Thr Glu Ile His Leu Ser Pro Gly 
            420                 425                 430         


Lys Phe Glu Val Leu Lys Asp Gly Arg Leu Val Asn Lys Asn Gly Ser 
        435                 440                 445             


Ser Gly Pro Ile Leu Thr Val Ser Leu Phe Gly Arg Trp Tyr Thr Lys 
    450                 455                 460                 


Asp Ser Leu Tyr Ser Ser Cys 
465                 470     


<210>  1892
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1892

His Trp Arg Arg Thr Ala His Val Gly Thr Asn Ile Leu Thr Ala Val 
1               5                   10                  15      


Ser Tyr Leu Lys Gly Leu Trp Met Glu Cys Val Trp His Ser Thr Gly 
            20                  25                  30          


Ile Tyr Gln Cys Gln Ile Tyr Arg Ser Leu Leu Ala Leu Pro Gln Asp 
        35                  40                  45              


Leu Gln Ala Ala Arg 
    50              


<210>  1893
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  1893

Ala Ser Val Pro Leu Ala Ala Ser Pro Ala Arg Ala Leu Pro Gly Gly 
1               5                   10                  15      


Ala Asp Asn Ala Ser Val Ala Ser Gly Ala Ala Ala Ser Pro Gly Pro 
            20                  25                  30          


Gln Arg Ser Leu Ser Ala Leu His Gly Ala Gly Gly Ser Ala Gly Pro 
        35                  40                  45              


Pro Ala Leu Pro Gly Ala Pro Ala Ala Ser Ala His Pro Leu Pro Pro 
    50                  55                  60                  


Gly Pro Leu Phe Ser Arg Phe Leu Cys Thr Pro Leu Ala Ala Ala Cys 
65                  70                  75                  80  


Pro Ser Gly Ala Gln Gln Gly Asp Ala Ala Gly Ala Ala Pro Gly Glu 
                85                  90                  95      


Arg Glu Glu Leu Leu Leu Leu Gln Ser Thr Ala Glu Gln Leu Arg Gln 
            100                 105                 110         


Thr Ala Leu Gln Gln Glu Ala Arg Ile Arg Ala Asp Gln Asp Thr Ile 
        115                 120                 125             


Arg Glu Leu Thr Gly Lys Leu Gly Arg Cys Glu Ser Gly Leu Pro Arg 
    130                 135                 140                 


Gly Leu Gln Gly Ala Gly Pro Arg Arg Asp Thr Met Ala Asp Gly Pro 
145                 150                 155                 160 


Trp Asp Ser Pro Ala Leu Ile Leu Glu Leu Glu Asp Ala Val Arg Ala 
                165                 170                 175     


Leu Arg Asp Arg Ile Asp Arg Leu Glu Gln Glu Leu Pro Ala Arg Val 
            180                 185                 190         


Asn Leu Ser Ala Ala Pro Ala Pro Val Ser Ala Val Pro Thr Gly Leu 
        195                 200                 205             


His Ser Lys Met Asp Gln Leu Glu Gly Gln Leu Leu Ala Gln Val Leu 
    210                 215                 220                 


Ala Leu Glu Lys Glu Arg Val Ala Leu Ser His Ser Ser Arg Arg Gln 
225                 230                 235                 240 


Arg Gln Glu Val Glu Lys Glu Leu Asp Val Leu Gln Gly Arg Val Ala 
                245                 250                 255     


Glu Leu Glu His Gly Ser Ser Ala Tyr Ser Pro Pro Asp Ala Phe Lys 
            260                 265                 270         


Ile Ser Ile Pro Ile Arg Asn Asn Tyr Met Tyr Ala Arg Val Arg Lys 
        275                 280                 285             


Ala Leu Pro Glu Leu Tyr Ala Phe Thr Ala Cys Met Trp Leu Arg Ser 
    290                 295                 300                 


Arg Ser Ser Gly Thr Gly Gln Gly Thr Pro Phe Ser Tyr Ser Val Pro 
305                 310                 315                 320 


Gly Gln Ala Asn Glu Ile Val Leu Leu Glu Ala Gly His Glu Pro Met 
                325                 330                 335     


Glu Leu Leu Ile Asn Asp Lys Val Ala Gln Leu Pro Leu Ser Leu Lys 
            340                 345                 350         


Asp Asn Gly Trp His His Ile Cys Ile Ala Trp Thr Thr Arg Asp Gly 
        355                 360                 365             


Leu Trp Ser Ala Tyr Gln Asp Gly Glu Leu Gln Gly Ser Gly Glu Asn 
    370                 375                 380                 


Leu Ala Ala Trp His Pro Ile Lys Pro His Gly Ile Leu Ile Leu Gly 
385                 390                 395                 400 


Gln Glu Gln Asp Thr Leu Gly Gly Arg Phe Asp Ala Thr Gln Ala Phe 
                405                 410                 415     


Val Gly Asp Ile Ala Gln Phe Asn Leu Trp Asp His Ala Leu Thr Pro 
            420                 425                 430         


Ala Gln Val Leu Gly Ile Ala Asn Cys Thr Ala Pro Leu Leu Gly Asn 
        435                 440                 445             


Val Leu Pro Trp Glu Asp Lys Leu Val Glu Ala Phe Gly Gly Ala Thr 
    450                 455                 460                 


Lys Ala Ala Phe Asp Val Cys Lys Gly Arg Ala Lys Ala 
465                 470                 475         


<210>  1894
<211>  95
<212>  PRT
<213>  Homo Sapiens

<400>  1894

Ala Val Pro Met Asp Ser Gly Pro Ser Cys Leu Ala Val Pro Asn Ala 
1               5                   10                  15      


Thr Gly Gln Thr Gly Leu Pro Gly Asp Ser Gly Leu Leu Gln Asp Ser 
            20                  25                  30          


Ser Leu Pro Pro Ile Pro Arg Thr Asn Glu Asp Gln Arg Glu Pro Ile 
        35                  40                  45              


Leu Ser Thr Ala Lys Lys Thr Lys Pro His Pro Arg Ser Gly Asp Pro 
    50                  55                  60                  


Ser Ala Pro Pro Arg Leu Ala Leu Ser Ser Ala Leu Pro Gly Pro Pro 
65                  70                  75                  80  


Leu Pro Ala Arg Gly His Ala Leu Leu Arg Trp Thr Ala Leu Leu 
                85                  90                  95  


<210>  1895
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1895

Asn Ser Arg Asp Leu Leu Gly Cys Leu Ala Gln Glu His Asn Ile Ser 
1               5                   10                  15      


Ala Ser Gln Val Asn Ala Cys His Val Ala Glu Ser Ala Val Asn Tyr 
            20                  25                  30          


Ser Leu Gly Asp Glu Gln Gly Phe Cys Gly Ser Pro Trp Pro Asn Cys 
        35                  40                  45              


Asn Phe Pro Glu Tyr 
    50              


<210>  1896
<211>  142
<212>  PRT
<213>  Homo Sapiens

<400>  1896

Gly Gly Gly Gly Lys Ala Trp Pro Thr His Val Val Cys Ser Asp Ser 
1               5                   10                  15      


Gly Leu Glu Val Leu Tyr Gln Ser Cys Asp Pro Leu Gln Asp Phe Gly 
            20                  25                  30          


Phe Ser Val Glu Lys Cys Ser Lys Gln Leu Lys Ser Asn Ile Asn Ile 
        35                  40                  45              


Arg Phe Gly Ile Ile Leu Arg Glu Asp Ile Lys Glu Leu Phe Leu Asp 
    50                  55                  60                  


Leu Ala Leu Met Ser Gln Gly Ser Ser Val Leu Asn Phe Ser Tyr Pro 
65                  70                  75                  80  


Ile Cys Glu Ala Ala Leu Pro Lys Phe Ser Phe Cys Gly Arg Arg Lys 
                85                  90                  95      


Gly Glu Gln Ile Tyr Tyr Ala Gly Pro Val Asn Asn Pro Glu Phe Thr 
            100                 105                 110         


Ile Pro Gln Gly Glu Tyr Gln Val Leu Leu Glu Leu Tyr Thr Glu Lys 
        115                 120                 125             


Arg Ser Thr Val Ala Cys Ala Asn Ala Thr Ile Met Cys Ser 
    130                 135                 140         


<210>  1897
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  1897

Thr Arg His Gln Asp Gly Arg Gln Asn Gln Ser Ser Leu Ser Pro Val 
1               5                   10                  15      


Leu Leu Pro Arg Asn Gln Arg Glu Leu Pro Thr Gly Asn His Glu Glu 
            20                  25                  30          


Ala Glu Glu Lys Pro Asp Leu Phe Val Ala Val Pro His Leu Val Gly 
        35                  40                  45              


Thr Ser Pro Ala Gly Glu Gly Gln Arg Gln Arg Glu Lys Met Leu Ser 
    50                  55                  60                  


Arg Phe Gly Arg Phe Trp Lys Lys Pro Glu Arg Glu Met His Pro Ser 
65                  70                  75                  80  


Arg Asp Ser Asp Ser Glu Pro Phe Pro Pro Gly Thr Gln Ser Leu Ile 
                85                  90                  95      


Gln Pro Ile Asp Gly Met Lys Met Glu Lys Ser Pro Leu Arg Glu Glu 
            100                 105                 110         


Ala Lys Lys Phe Trp His His Phe Met Phe Arg Lys Thr Pro Ala Ser 
        115                 120                 125             


Gln Gly Val Ile Leu Pro Ile Lys Ser His Glu Val His Trp Glu Thr 
    130                 135                 140                 


Cys Arg Thr Val Pro Phe Ser Gln Thr Ile Thr His Glu Gly Cys Glu 
145                 150                 155                 160 


Lys Val Val Val Gln Asn Asn Leu Cys Phe Gly Lys Cys Gly Ser Val 
                165                 170                 175     


His Phe Pro Gly Ala Ala Gln His Ser His Thr Ser Cys Ser His Cys 
            180                 185                 190         


Leu Pro Ala Lys Phe Thr Thr Met His Leu Pro Leu Asn Cys Thr Glu 
        195                 200                 205             


Leu Ser Ser Val Ile Lys Val Val Met Leu Val Glu Glu Cys Gln Cys 
    210                 215                 220                 


Lys Val Lys Thr Glu His Glu Asp Gly His Ile Leu His Ala Gly Ser 
225                 230                 235                 240 


Gln Asp Ser Phe Ile Pro Gly Val Ser Ala 
                245                 250 


<210>  1898
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1898

Gln Trp Arg Ile Tyr Ser Tyr Ala Gly Asp Asn Ile Val Thr Ala Gln 
1               5                   10                  15      


Ala Met Tyr Glu Gly Leu Trp Met Ser Cys Val Ser Gln Ser Thr Gly 
            20                  25                  30          


Gln Ile Gln Cys Lys Val Phe Asp Ser Leu Leu Asn Leu Ser Ser Thr 
        35                  40                  45              


Leu Gln Ala Thr Arg 
    50              


<210>  1899
<211>  146
<212>  PRT
<213>  Homo Sapiens

<400>  1899

His Asn Gly Leu Gly Lys Gly Phe Gly Asp His Ile His Trp Arg Thr 
1               5                   10                  15      


Leu Glu Asp Gly Lys Lys Glu Ala Ala Ala Ser Gly Leu Pro Leu Met 
            20                  25                  30          


Val Ile Ile His Lys Ser Trp Cys Gly Ala Cys Lys Ala Leu Lys Pro 
        35                  40                  45              


Lys Phe Ala Glu Ser Thr Glu Ile Ser Glu Leu Ser His Asn Phe Val 
    50                  55                  60                  


Met Val Asn Leu Glu Asp Glu Glu Glu Pro Lys Asp Glu Asp Phe Ser 
65                  70                  75                  80  


Pro Asp Gly Gly Tyr Ile Pro Arg Ile Leu Phe Leu Asp Pro Ser Gly 
                85                  90                  95      


Lys Val His Pro Glu Ile Ile Asn Glu Asn Gly Asn Pro Ser Tyr Lys 
            100                 105                 110         


Tyr Phe Tyr Val Ser Ala Glu Gln Val Val Gln Gly Met Lys Glu Ala 
        115                 120                 125             


Gln Glu Arg Leu Thr Gly Asp Ala Phe Arg Lys Lys His Leu Glu Asp 
    130                 135                 140                 


Glu Leu 
145     


<210>  1900
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  1900

Gln Thr Leu Phe Gln Asn Pro Glu Glu Gly Trp Gln Leu Tyr Thr Ser 
1               5                   10                  15      


Ala Gln Ala Pro Asp Gly Lys Cys Ile Cys Thr Ala Val Ile Pro Ala 
            20                  25                  30          


Gln Ser Thr Cys Ser Arg Asp Gly Arg Ser Arg Glu Leu Arg Gln Leu 
        35                  40                  45              


Met Glu Lys Val Gln Asn Val Ser Gln Ser Met Glu Val Leu Glu Leu 
    50                  55                  60                  


Arg Thr Tyr Arg Asp Leu Gln Tyr Val Arg Gly Met Glu Thr Leu Met 
65                  70                  75                  80  


Arg Ser Leu Asp Ala Arg Leu Arg Ala Ala Asp Gly Ser Leu Ser Ala 
                85                  90                  95      


Lys Ser Phe Gln Glu Leu Lys Asp Arg Met Thr Glu Leu Leu Pro Leu 
            100                 105                 110         


Ser Ser Val Leu Glu Gln Tyr Lys Ala Asp Thr Arg Thr Ile Val Arg 
        115                 120                 125             


Leu Arg Glu Glu Val Arg Asn Leu Ser Gly Ser Leu Ala Ala Ile Gln 
    130                 135                 140                 


Glu Glu Met Gly Ala Tyr Gly Tyr Glu Asp Leu Gln Gln Arg Val Met 
145                 150                 155                 160 


Ala Leu Glu Ala Arg Leu His Ala Cys Ala Gln Lys Leu Gly Cys Gly 
                165                 170                 175     


Lys Leu Thr Gly Val Ser Asn Pro Ile Thr Val Arg Ala Met Gly Ser 
            180                 185                 190         


Arg Phe Gly Ser Trp Met Thr Asp Thr Met Ala Pro Ser Ala Asp Ser 
        195                 200                 205             


Arg Val Trp Tyr Met Asp Gly Tyr Tyr Lys Gly Arg Arg Val Leu Glu 
    210                 215                 220                 


Phe Arg Thr Leu Gly Asp Phe Ile Lys Gly Gln Asn Phe Ile Gln His 
225                 230                 235                 240 


Leu Leu Pro Gln Pro Trp Ala Gly Thr Gly His Val Val Tyr Asn Gly 
                245                 250                 255     


Ser Leu Phe Tyr Asn Lys Tyr Gln Ser Asn Val Val Val Lys Tyr His 
            260                 265                 270         


Phe Arg Ser Arg Ser Val Leu Val Gln Arg Ser Leu Pro Gly Ala Gly 
        275                 280                 285             


Tyr Asn Asn Thr Phe Pro Tyr Ser Trp Gly Gly Phe Ser Asp Met Asp 
    290                 295                 300                 


Phe Met Val Asp Glu Ser Gly Leu Trp Ala Val Tyr Thr Thr Asn Gln 
305                 310                 315                 320 


Asn Ala Gly Asn Ile Val Val Ser Arg Leu Asp Pro His Thr Leu Glu 
                325                 330                 335     


Val Met Arg Ser Trp Asp Thr Gly Tyr Pro Lys Arg Ser Ala Gly Glu 
            340                 345                 350         


Ala Phe Met Ile Cys Gly Val Leu Tyr Val Thr Asn Ser His Leu Ala 
        355                 360                 365             


Gly Ala Lys Val Tyr Phe Ala Tyr Phe Thr Asn Thr Ser Ser Tyr Glu 
    370                 375                 380                 


Tyr Thr Asp Val Pro Phe His Asn Gln Tyr Ser His Ile Ser Met Leu 
385                 390                 395                 400 


Asp Tyr Asn Pro Arg Glu Arg Ala Leu Tyr Thr Trp Asn Asn Gly His 
                405                 410                 415     


Gln Val Leu Tyr Asn Val Thr Leu Phe His Val Ile Ser Thr Ser Gly 
            420                 425                 430         


Asp Pro 
        


<210>  1901
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  1901

Pro Gly Leu Thr Asp Trp Leu Phe Pro Arg Arg Cys Pro Lys Ile Arg 
1               5                   10                  15      


Glu Glu Cys Glu Phe Gln Glu Arg Asp Val Cys Thr Lys Asp Arg Gln 
            20                  25                  30          


Cys Gln Asp Asn Lys Lys Cys Cys Val Phe Ser Cys Gly Lys Lys Cys 
        35                  40                  45              


Leu Asp Leu Lys Gln Asp Val Cys Glu Met Pro Lys Glu Thr Gly Pro 
    50                  55                  60                  


Cys Leu Ala Tyr Phe Leu His Trp Trp Tyr Asp Lys Lys Asp Asn Thr 
65                  70                  75                  80  


Cys Ser Met Phe Val Tyr Gly Gly Cys Gln Gly Asn Asn Asn Asn Phe 
                85                  90                  95      


Gln Ser Lys Ala Asn Cys Leu Asn Thr Cys Lys Asn Lys Arg Phe Pro 
            100                 105                 110         


<210>  1902
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1902

Val Val Cys Gln Ala Leu Gly Ser Glu Ile Thr Gly Phe Leu Leu Ala 
1               5                   10                  15      


Gly Lys Pro Val Phe Lys Phe Gln Leu Ala Lys Phe Lys Ala Pro Leu 
            20                  25                  30          


Glu Ala Val Ala Ala Lys Met Glu Val Lys Lys Cys Val Asp Thr Met 
        35                  40                  45              


Ala Tyr Glu Lys Arg Val Leu Ile Thr Lys Thr Leu Gly Lys Ile Ala 
    50                  55                  60                  


Glu Lys Cys Asp Arg 
65                  


<210>  1903
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1903

Glu Phe Cys Pro Ala Leu Val Ser Glu Leu Leu Asp Phe Phe Phe Ile 
1               5                   10                  15      


Ser Glu Pro Leu Phe Lys Leu Ser Leu Ala Lys Phe Asp Ala Pro Pro 
            20                  25                  30          


Glu Ala Val Ala Ala Lys Leu Gly Val Lys Arg Cys Thr Asp Gln Met 
        35                  40                  45              


Ser Leu Gln Lys Arg Ser Leu Ile Ala Glu Val Leu Val Lys Ile Leu 
    50                  55                  60                  


Lys Lys Cys Ser Val 
65                  


<210>  1904
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  1904

Arg Asp Thr Thr Val Lys Pro Gly Ala Lys Lys Asp Thr Lys Asp Ser 
1               5                   10                  15      


Arg Pro Lys Leu Pro Gln Thr Leu Ser Arg Gly Trp Gly Asp Gln Leu 
            20                  25                  30          


Ile Trp Thr Gln Thr Tyr Glu Glu Ala Leu Tyr Lys Ser Lys Thr Ser 
        35                  40                  45              


Asn Lys Pro Leu Met Ile Ile His His Leu Asp Glu Cys Pro His Ser 
    50                  55                  60                  


Gln Ala Leu Lys Lys Val Phe Ala Glu Asn Lys Glu Ile Gln Lys Leu 
65                  70                  75                  80  


Ala Glu Gln Phe Val Leu Leu Asn Leu Val Tyr Glu Thr Thr Asp Lys 
                85                  90                  95      


His Leu Ser Pro Asp Gly Gln Tyr Val Pro Arg Ile Met Phe Val Asp 
            100                 105                 110         


Pro Ser Leu Thr Val Arg Ala Asp Ile Thr Gly Arg Tyr Ser Asn Arg 
        115                 120                 125             


Leu Tyr Ala Tyr Glu Pro Ala Asp Thr Ala Leu Leu Leu Asp Asn Met 
    130                 135                 140                 


Lys Lys Ala Leu Lys Leu Leu Lys Thr Glu Leu 
145                 150                 155 


<210>  1905
<211>  353
<212>  PRT
<213>  Homo Sapiens

<400>  1905

Ala Ala Ala Gln Glu Ala Asp Gly Ala Arg Ser Ala Val Val Ala Ala 
1               5                   10                  15      


Gly Gly Gly Ser Ser Gly Gln Val Thr Ser Asn Gly Ser Ile Gly Arg 
            20                  25                  30          


Asp Pro Pro Ala Glu Thr Gln Pro Gln Asn Pro Pro Ala Gln Pro Ala 
        35                  40                  45              


Pro Asn Ala Trp Gln Val Ile Lys Gly Val Leu Phe Arg Ile Phe Ile 
    50                  55                  60                  


Ile Trp Ala Ile Ser Ser Trp Phe Arg Arg Gly Pro Ala Pro Gln Asp 
65                  70                  75                  80  


Gln Ala Gly Pro Gly Gly Ala Pro Arg Val Ala Ser Arg Asn Leu Phe 
                85                  90                  95      


Pro Lys Asp Thr Leu Met Asn Leu His Val Tyr Ile Ser Glu His Glu 
            100                 105                 110         


His Phe Thr Asp Phe Asn Ala Thr Ser Ala Leu Phe Trp Glu Gln His 
        115                 120                 125             


Asp Leu Val Tyr Gly Asp Trp Thr Ser Gly Glu Asn Ser Asp Gly Cys 
    130                 135                 140                 


Tyr Glu His Phe Ala Glu Leu Asp Ile Pro Gln Ser Val Gln Gln Asn 
145                 150                 155                 160 


Gly Ser Ile Tyr Ile His Val Tyr Phe Thr Lys Ser Gly Phe His Pro 
                165                 170                 175     


Asp Pro Arg Gln Lys Ala Leu Tyr Arg Arg Leu Ala Thr Val His Met 
            180                 185                 190         


Ser Arg Met Ile Asn Lys Tyr Lys Arg Arg Arg Phe Gln Lys Thr Lys 
        195                 200                 205             


Asn Leu Leu Thr Gly Glu Thr Glu Ala Asp Pro Glu Met Ile Lys Arg 
    210                 215                 220                 


Ala Glu Asp Tyr Gly Pro Val Glu Val Ile Ser His Trp His Pro Asn 
225                 230                 235                 240 


Ile Thr Ile Asn Ile Val Asp Asp His Thr Pro Trp Val Lys Gly Ser 
                245                 250                 255     


Val Pro Pro Pro Leu Asp Gln Tyr Val Lys Phe Asp Ala Val Ser Gly 
            260                 265                 270         


Asp Tyr Tyr Pro Ile Ile Tyr Phe Asn Asp Tyr Trp Asn Leu Gln Lys 
        275                 280                 285             


Asp Tyr Tyr Pro Ile Asn Glu Ser Leu Ala Ser Leu Pro Leu Arg Val 
    290                 295                 300                 


Ser Phe Cys Pro Leu Ser Leu Trp Arg Trp Gln Leu Tyr Ala Ala Gln 
305                 310                 315                 320 


Ser Thr Lys Ser Pro Trp Asn Phe Leu Gly Asp Glu Leu Tyr Glu Gln 
                325                 330                 335     


Ser Asp Glu Glu Gln Asp Ser Val Lys Val Ala Leu Leu Glu Thr Asn 
            340                 345                 350         


Pro 
    


<210>  1906
<211>  357
<212>  PRT
<213>  Homo Sapiens

<400>  1906

Lys Pro Ile Phe Val Pro Leu Ser Asn Tyr Arg Asp Val Gln Tyr Phe 
1               5                   10                  15      


Gly Glu Ile Gly Leu Gly Thr Pro Pro Gln Asn Phe Thr Val Ala Phe 
            20                  25                  30          


Asp Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Arg Arg Cys His Phe 
        35                  40                  45              


Phe Ser Val Pro Cys Trp Leu His His Arg Phe Asp Pro Lys Ala Ser 
    50                  55                  60                  


Ser Ser Phe Gln Ala Asn Gly Thr Lys Phe Ala Ile Gln Tyr Gly Thr 
65                  70                  75                  80  


Gly Arg Val Asp Gly Ile Leu Ser Glu Asp Lys Leu Thr Ile Gly Gly 
                85                  90                  95      


Ile Lys Gly Ala Ser Val Ile Phe Gly Glu Ala Leu Trp Glu Pro Ser 
            100                 105                 110         


Leu Val Phe Ala Phe Ala His Phe Asp Gly Ile Leu Gly Leu Gly Phe 
        115                 120                 125             


Pro Ile Leu Ser Val Glu Gly Val Arg Pro Pro Met Asp Val Leu Val 
    130                 135                 140                 


Glu Gln Gly Leu Leu Asp Lys Pro Val Phe Ser Phe Tyr Leu Asn Arg 
145                 150                 155                 160 


Asp Pro Glu Glu Pro Asp Gly Gly Glu Leu Val Leu Gly Gly Ser Asp 
                165                 170                 175     


Pro Ala His Tyr Ile Pro Pro Leu Thr Phe Val Pro Val Thr Val Pro 
            180                 185                 190         


Ala Tyr Trp Gln Ile His Met Glu Arg Val Lys Val Gly Pro Gly Leu 
        195                 200                 205             


Thr Leu Cys Ala Lys Gly Cys Ala Ala Ile Leu Asp Thr Gly Thr Ser 
    210                 215                 220                 


Leu Ile Thr Gly Pro Thr Glu Glu Ile Arg Ala Leu His Ala Ala Ile 
225                 230                 235                 240 


Gly Gly Ile Pro Leu Leu Ala Gly Glu Tyr Ile Ile Leu Cys Ser Glu 
                245                 250                 255     


Ile Pro Lys Leu Pro Ala Val Ser Phe Leu Leu Gly Gly Val Trp Phe 
            260                 265                 270         


Asn Leu Thr Ala His Asp Tyr Val Ile Gln Thr Thr Arg Asn Gly Val 
        275                 280                 285             


Arg Leu Cys Leu Ser Gly Phe Gln Ala Leu Asp Val Pro Pro Pro Ala 
    290                 295                 300                 


Gly Pro Phe Trp Ile Leu Gly Asp Val Phe Leu Gly Thr Tyr Val Ala 
305                 310                 315                 320 


Val Phe Asp Arg Gly Asp Met Lys Ser Ser Ala Arg Val Gly Leu Ala 
                325                 330                 335     


Arg Ala Arg Thr Arg Gly Ala Asp Leu Gly Trp Gly Glu Thr Ala Gln 
            340                 345                 350         


Ala Gln Phe Pro Gly 
        355         


<210>  1907
<211>  330
<212>  PRT
<213>  Homo Sapiens

<400>  1907

Ile Lys Trp Leu Ala Leu Ser Lys Thr Pro Ser Ala Leu Ala Leu Asn 
1               5                   10                  15      


Gln Thr Gln His Cys Lys Gln Leu Glu Gly Leu Val Ser Ala Gln Val 
            20                  25                  30          


Gln Leu Cys Arg Ser Asn Leu Glu Leu Met His Thr Val Val His Ala 
        35                  40                  45              


Ala Arg Glu Val Met Lys Ala Cys Arg Arg Ala Phe Ala Asp Met Arg 
    50                  55                  60                  


Trp Asn Cys Ser Ser Ile Glu Leu Ala Pro Asn Tyr Leu Leu Asp Leu 
65                  70                  75                  80  


Glu Arg Gly Thr Arg Glu Ser Ala Phe Val Tyr Ala Leu Ser Ala Ala 
                85                  90                  95      


Ala Ile Ser His Ala Ile Ala Arg Ala Cys Thr Ser Gly Asp Leu Pro 
            100                 105                 110         


Gly Cys Ser Cys Gly Pro Val Pro Gly Glu Pro Pro Gly Pro Gly Asn 
        115                 120                 125             


Arg Trp Gly Gly Cys Ala Asp Asn Leu Ser Tyr Gly Leu Leu Met Gly 
    130                 135                 140                 


Ala Lys Phe Ser Asp Ala Pro Met Lys Val Lys Lys Thr Gly Ser Gln 
145                 150                 155                 160 


Ala Asn Lys Leu Met Arg Leu His Asn Ser Glu Val Gly Arg Gln Ala 
                165                 170                 175     


Leu Arg Ala Ser Leu Glu Met Lys Cys Lys Cys His Gly Val Ser Gly 
            180                 185                 190         


Ser Cys Ser Ile Arg Thr Cys Trp Lys Gly Leu Gln Glu Leu Gln Asp 
        195                 200                 205             


Val Ala Ala Asp Leu Lys Thr Arg Tyr Leu Ser Ala Thr Lys Val Val 
    210                 215                 220                 


His Arg Pro Met Gly Thr Arg Lys His Leu Val Pro Lys Asp Leu Asp 
225                 230                 235                 240 


Ile Arg Pro Val Lys Asp Ser Glu Leu Val Tyr Leu Gln Ser Ser Pro 
                245                 250                 255     


Asp Phe Ser Met Lys Asn Glu Lys Val Gly Ser His Gly Thr Gln Asp 
            260                 265                 270         


Arg Gln Cys Asn Lys Thr Ser Asn Gly Ser Asp Ser Cys Asp Leu Met 
        275                 280                 285             


Cys Cys Gly Arg Gly Tyr Asn Pro Tyr Thr Asp Arg Val Val Glu Arg 
    290                 295                 300                 


Cys His Cys Lys Tyr His Trp Cys Cys Tyr Val Thr Cys Arg Arg Cys 
305                 310                 315                 320 


Glu Arg Thr Val Glu Arg Tyr Val Cys Lys 
                325                 330 


<210>  1908
<211>  1046
<212>  PRT
<213>  Homo Sapiens

<400>  1908

Lys Glu Lys His Tyr Tyr Ile Gly Ile Ile Glu Thr Thr Trp Asp Tyr 
1               5                   10                  15      


Ala Ser Asp His Gly Glu Lys Lys Leu Ile Ser Val Asp Thr Glu His 
            20                  25                  30          


Ser Asn Ile Tyr Leu Gln Asn Gly Pro Asp Arg Ile Gly Arg Leu Tyr 
        35                  40                  45              


Lys Lys Ala Leu Tyr Leu Gln Tyr Thr Asp Glu Thr Phe Arg Thr Thr 
    50                  55                  60                  


Ile Glu Lys Pro Val Trp Leu Gly Phe Leu Gly Pro Ile Ile Lys Ala 
65                  70                  75                  80  


Glu Thr Gly Asp Lys Val Tyr Val His Leu Lys Asn Leu Ala Ser Arg 
                85                  90                  95      


Pro Tyr Thr Phe His Ser His Gly Ile Thr Tyr Tyr Lys Glu His Glu 
            100                 105                 110         


Gly Ala Ile Tyr Pro Asp Asn Thr Thr Asp Phe Gln Arg Ala Asp Asp 
        115                 120                 125             


Lys Val Tyr Pro Gly Glu Gln Tyr Thr Tyr Met Leu Leu Ala Thr Glu 
    130                 135                 140                 


Glu Gln Ser Pro Gly Glu Gly Asp Gly Asn Cys Val Thr Arg Ile Tyr 
145                 150                 155                 160 


His Ser His Ile Asp Ala Pro Lys Asp Ile Ala Ser Gly Leu Ile Gly 
                165                 170                 175     


Pro Leu Ile Ile Cys Lys Lys Asp Ser Leu Asp Lys Glu Lys Glu Lys 
            180                 185                 190         


His Ile Asp Arg Glu Phe Val Val Met Phe Ser Val Val Asp Glu Asn 
        195                 200                 205             


Phe Ser Trp Tyr Leu Glu Asp Asn Ile Lys Thr Tyr Cys Ser Glu Pro 
    210                 215                 220                 


Glu Lys Val Asp Lys Asp Asn Glu Asp Phe Gln Glu Ser Asn Arg Met 
225                 230                 235                 240 


Tyr Ser Val Asn Gly Tyr Thr Phe Gly Ser Leu Pro Gly Leu Ser Met 
                245                 250                 255     


Cys Ala Glu Asp Arg Val Lys Trp Tyr Leu Phe Gly Met Gly Asn Glu 
            260                 265                 270         


Val Asp Val His Ala Ala Phe Phe His Gly Gln Ala Leu Thr Asn Lys 
        275                 280                 285             


Asn Tyr Arg Ile Asp Thr Ile Asn Leu Phe Pro Ala Thr Leu Phe Asp 
    290                 295                 300                 


Ala Tyr Met Val Ala Gln Asn Pro Gly Glu Trp Met Leu Ser Cys Gln 
305                 310                 315                 320 


Asn Leu Asn His Leu Lys Ala Gly Leu Gln Ala Phe Phe Gln Val Gln 
                325                 330                 335     


Glu Cys Asn Lys Ser Ser Ser Lys Asp Asn Ile Arg Gly Lys His Val 
            340                 345                 350         


Arg His Tyr Tyr Ile Ala Ala Glu Glu Ile Ile Trp Asn Tyr Ala Pro 
        355                 360                 365             


Ser Gly Ile Asp Ile Phe Thr Lys Glu Asn Leu Thr Ala Pro Gly Ser 
    370                 375                 380                 


Asp Ser Ala Val Phe Phe Glu Gln Gly Thr Thr Arg Ile Gly Gly Ser 
385                 390                 395                 400 


Tyr Lys Lys Leu Val Tyr Arg Glu Tyr Thr Asp Ala Ser Phe Thr Asn 
                405                 410                 415     


Arg Lys Glu Arg Gly Pro Glu Glu Glu His Leu Gly Ile Leu Gly Pro 
            420                 425                 430         


Val Ile Trp Ala Glu Val Gly Asp Thr Ile Arg Val Thr Phe His Asn 
        435                 440                 445             


Lys Gly Ala Tyr Pro Leu Ser Ile Glu Pro Ile Gly Val Arg Phe Asn 
    450                 455                 460                 


Lys Asn Asn Glu Gly Thr Tyr Tyr Ser Pro Asn Tyr Asn Pro Gln Ser 
465                 470                 475                 480 


Arg Ser Val Pro Pro Ser Ala Ser His Val Ala Pro Thr Glu Thr Phe 
                485                 490                 495     


Thr Tyr Glu Trp Thr Val Pro Lys Glu Val Gly Pro Thr Asn Ala Asp 
            500                 505                 510         


Pro Val Cys Leu Ala Lys Met Tyr Tyr Ser Ala Val Asp Pro Thr Lys 
        515                 520                 525             


Asp Ile Phe Thr Gly Leu Ile Gly Pro Met Lys Ile Cys Lys Lys Gly 
    530                 535                 540                 


Ser Leu His Ala Asn Gly Arg Gln Lys Asp Val Asp Lys Glu Phe Tyr 
545                 550                 555                 560 


Leu Phe Pro Thr Val Phe Asp Glu Asn Glu Ser Leu Leu Leu Glu Asp 
                565                 570                 575     


Asn Ile Arg Met Phe Thr Thr Ala Pro Asp Gln Val Asp Lys Glu Asp 
            580                 585                 590         


Glu Asp Phe Gln Glu Ser Asn Lys Met His Ser Met Asn Gly Phe Met 
        595                 600                 605             


Tyr Gly Asn Gln Pro Gly Leu Thr Met Cys Lys Gly Asp Ser Val Val 
    610                 615                 620                 


Trp Tyr Leu Phe Ser Ala Gly Asn Glu Ala Asp Val His Gly Ile Tyr 
625                 630                 635                 640 


Phe Ser Gly Asn Thr Tyr Leu Trp Arg Gly Glu Arg Arg Asp Thr Ala 
                645                 650                 655     


Asn Leu Phe Pro Gln Thr Ser Leu Thr Leu His Met Trp Pro Asp Thr 
            660                 665                 670         


Glu Gly Thr Phe Asn Val Glu Cys Leu Thr Thr Asp His Tyr Thr Gly 
        675                 680                 685             


Gly Met Lys Gln Lys Tyr Thr Val Asn Gln Cys Arg Arg Gln Ser Glu 
    690                 695                 700                 


Asp Ser Thr Phe Tyr Leu Gly Glu Arg Thr Tyr Tyr Ile Ala Ala Val 
705                 710                 715                 720 


Glu Val Glu Trp Asp Tyr Ser Pro Gln Arg Glu Trp Glu Lys Glu Leu 
                725                 730                 735     


His His Leu Gln Glu Gln Asn Val Ser Asn Ala Phe Leu Asp Lys Gly 
            740                 745                 750         


Glu Phe Tyr Ile Gly Ser Lys Tyr Lys Lys Val Val Tyr Arg Gln Tyr 
        755                 760                 765             


Thr Asp Ser Thr Phe Arg Val Pro Val Glu Arg Lys Ala Glu Glu Glu 
    770                 775                 780                 


His Leu Gly Ile Leu Gly Pro Gln Leu His Ala Asp Val Gly Asp Lys 
785                 790                 795                 800 


Val Lys Ile Ile Phe Lys Asn Met Ala Thr Arg Pro Tyr Ser Ile His 
                805                 810                 815     


Ala His Gly Val Gln Thr Glu Ser Ser Thr Val Thr Pro Thr Leu Pro 
            820                 825                 830         


Gly Glu Thr Leu Thr Tyr Val Trp Lys Ile Pro Glu Arg Ser Gly Ala 
        835                 840                 845             


Gly Thr Glu Asp Ser Ala Cys Ile Pro Trp Ala Tyr Tyr Ser Thr Val 
    850                 855                 860                 


Asp Gln Val Lys Asp Leu Tyr Ser Gly Leu Ile Gly Pro Leu Ile Val 
865                 870                 875                 880 


Cys Arg Arg Pro Tyr Leu Lys Val Phe Asn Pro Arg Arg Lys Leu Glu 
                885                 890                 895     


Phe Ala Leu Leu Phe Leu Val Phe Asp Glu Asn Glu Ser Trp Tyr Leu 
            900                 905                 910         


Asp Asp Asn Ile Lys Thr Tyr Ser Asp His Pro Glu Lys Val Asn Lys 
        915                 920                 925             


Asp Asp Glu Glu Phe Ile Glu Ser Asn Lys Met His Ala Ile Asn Gly 
    930                 935                 940                 


Arg Met Phe Gly Asn Leu Gln Gly Leu Thr Met His Val Gly Asp Glu 
945                 950                 955                 960 


Val Asn Trp Tyr Leu Met Gly Met Gly Asn Glu Ile Asp Leu His Thr 
                965                 970                 975     


Val His Phe His Gly His Ser Phe Gln Tyr Lys His Arg Gly Val Tyr 
            980                 985                 990         


Ser Ser Asp Val Phe Asp Ile Phe  Pro Gly Thr Tyr Gln  Thr Leu Glu 
        995                 1000                 1005             


Met Phe  Pro Arg Thr Pro Gly  Ile Trp Leu Leu His  Cys His Val 
    1010                 1015                 1020             


Thr Asp  His Ile His Ala Gly  Met Glu Thr Thr Tyr  Thr Val Leu 
    1025                 1030                 1035             


Gln Asn  Glu Asp Thr Lys Ser  Gly 
    1040                 1045     


<210>  1909
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  1909

Lys Gln Phe Thr Lys Cys Glu Leu Ser Gln Leu Leu Lys Asp Ile Asp 
1               5                   10                  15      


Gly Tyr Gly Gly Ile Ala Leu Pro Glu Leu Ile Cys Thr Met Phe His 
            20                  25                  30          


Thr Ser Gly Tyr Asp Thr Gln Ala Ile Val Glu Asn Asn Glu Ser Thr 
        35                  40                  45              


Glu Tyr Gly Leu Phe Gln Ile Ser Asn Lys Leu Trp Cys Lys Ser Ser 
    50                  55                  60                  


Gln Val Pro Gln Ser Arg Asn Ile Cys Asp Ile Ser Cys Asp Lys Phe 
65                  70                  75                  80  


Leu Asp Asp Asp Ile Thr Asp Asp Ile Met Cys Ala Lys Lys Ile Leu 
                85                  90                  95      


Asp Ile Lys Gly Ile Asp Tyr Trp Leu Ala His Lys Ala Leu Cys Thr 
            100                 105                 110         


Glu Lys Leu Glu Gln Trp Leu Cys Glu Lys Leu 
        115                 120             


<210>  1910
<211>  579
<212>  PRT
<213>  Homo Sapiens

<400>  1910

Ala Asn Thr Phe Leu Glu Glu Val Arg Lys Gly Asn Leu Glu Arg Glu 
1               5                   10                  15      


Cys Val Glu Glu Thr Cys Ser Tyr Glu Glu Ala Phe Glu Ala Leu Glu 
            20                  25                  30          


Ser Ser Thr Ala Thr Asp Val Phe Trp Ala Lys Tyr Thr Ala Cys Glu 
        35                  40                  45              


Thr Ala Arg Thr Pro Arg Asp Lys Leu Ala Ala Cys Leu Glu Gly Asn 
    50                  55                  60                  


Cys Ala Glu Gly Leu Gly Thr Asn Tyr Arg Gly His Val Asn Ile Thr 
65                  70                  75                  80  


Arg Ser Gly Ile Glu Cys Gln Leu Trp Arg Ser Arg Tyr Pro His Lys 
                85                  90                  95      


Pro Glu Ile Asn Ser Thr Thr His Pro Gly Ala Asp Leu Gln Glu Asn 
            100                 105                 110         


Phe Cys Arg Asn Pro Asp Ser Ser Thr Thr Gly Pro Trp Cys Tyr Thr 
        115                 120                 125             


Thr Asp Pro Thr Val Arg Arg Gln Glu Cys Ser Ile Pro Val Cys Gly 
    130                 135                 140                 


Gln Asp Gln Val Thr Val Ala Met Thr Pro Arg Ser Glu Gly Ser Ser 
145                 150                 155                 160 


Val Asn Leu Ser Pro Pro Leu Glu Gln Cys Val Pro Asp Arg Gly Gln 
                165                 170                 175     


Gln Tyr Gln Gly Arg Leu Ala Val Thr Thr His Gly Leu Pro Cys Leu 
            180                 185                 190         


Ala Trp Ala Ser Ala Gln Ala Lys Ala Leu Ser Lys His Gln Asp Phe 
        195                 200                 205             


Asn Ser Ala Val Gln Leu Val Glu Asn Phe Cys Arg Asn Pro Asp Gly 
    210                 215                 220                 


Asp Glu Glu Gly Ala Trp Cys Tyr Val Ala Gly Lys Pro Gly Asp Phe 
225                 230                 235                 240 


Gly Tyr Cys Asp Leu Asn Tyr Cys Glu Glu Ala Val Glu Glu Glu Thr 
                245                 250                 255     


Gly Asp Gly Leu Asp Glu Asp Ser Asp Arg Ala Ile Glu Gly Arg Thr 
            260                 265                 270         


Ala Thr Ser Glu Tyr Gln Thr Phe Phe Asn Pro Arg Thr Phe Gly Ser 
        275                 280                 285             


Gly Glu Ala Asp Cys Gly Leu Arg Pro Leu Phe Glu Lys Lys Ser Leu 
    290                 295                 300                 


Glu Asp Lys Thr Glu Arg Glu Leu Leu Glu Ser Tyr Ile Asp Gly Arg 
305                 310                 315                 320 


Ile Val Glu Gly Ser Asp Ala Glu Ile Gly Met Ser Pro Trp Gln Val 
                325                 330                 335     


Met Leu Phe Arg Lys Ser Pro Gln Glu Leu Leu Cys Gly Ala Ser Leu 
            340                 345                 350         


Ile Ser Asp Arg Trp Val Leu Thr Ala Ala His Cys Leu Leu Tyr Pro 
        355                 360                 365             


Pro Trp Asp Lys Asn Phe Thr Glu Asn Asp Leu Leu Val Arg Ile Gly 
    370                 375                 380                 


Lys His Ser Arg Thr Arg Tyr Glu Arg Asn Ile Glu Lys Ile Ser Met 
385                 390                 395                 400 


Leu Glu Lys Ile Tyr Ile His Pro Arg Tyr Asn Trp Arg Glu Asn Leu 
                405                 410                 415     


Asp Arg Asp Ile Ala Leu Met Lys Leu Lys Lys Pro Val Ala Phe Ser 
            420                 425                 430         


Asp Tyr Ile His Pro Val Cys Leu Pro Asp Arg Glu Thr Ala Ala Ser 
        435                 440                 445             


Leu Leu Gln Ala Gly Tyr Lys Gly Arg Val Thr Gly Trp Gly Asn Leu 
    450                 455                 460                 


Lys Glu Thr Trp Thr Ala Asn Val Gly Lys Gly Gln Pro Ser Val Leu 
465                 470                 475                 480 


Gln Val Val Asn Leu Pro Ile Val Glu Arg Pro Val Cys Lys Asp Ser 
                485                 490                 495     


Thr Arg Ile Arg Ile Thr Asp Asn Met Phe Cys Ala Gly Tyr Lys Pro 
            500                 505                 510         


Asp Glu Gly Lys Arg Gly Asp Ala Cys Glu Gly Asp Ser Gly Gly Pro 
        515                 520                 525             


Phe Val Met Lys Ser Pro Phe Asn Asn Arg Trp Tyr Gln Met Gly Ile 
    530                 535                 540                 


Val Ser Trp Gly Glu Gly Cys Asp Arg Asp Gly Lys Tyr Gly Phe Tyr 
545                 550                 555                 560 


Thr His Val Phe Arg Leu Lys Lys Trp Ile Gln Lys Val Ile Asp Gln 
                565                 570                 575     


Phe Gly Glu 
            


<210>  1911
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  1911

Thr Pro Trp Ser Leu Ala Trp Pro Gln Gly Ser Cys Ser Leu Glu Gly 
1               5                   10                  15      


Val Glu Ile Lys Gly Gly Ser Phe Arg Leu Leu Gln Glu Gly Gln Ala 
            20                  25                  30          


Leu Glu Tyr Val Cys Pro Ser Gly Phe Tyr Pro Tyr Pro Val Gln Thr 
        35                  40                  45              


Arg Thr Cys Arg Ser Thr Gly Ser Trp Ser Thr Leu Lys Thr Gln Asp 
    50                  55                  60                  


Gln Lys Thr Val Arg Lys Ala Glu Cys Arg Ala Ile His Cys Pro Arg 
65                  70                  75                  80  


Pro His Asp Phe Glu Asn Gly Glu Tyr Trp Pro Arg Ser Pro Tyr Tyr 
                85                  90                  95      


Asn Val Ser Asp Glu Ile Ser Phe His Cys Tyr Asp Gly Tyr Thr Leu 
            100                 105                 110         


Arg Gly Ser Ala Asn Arg Thr Cys Gln Val Asn Gly Arg Trp Ser Gly 
        115                 120                 125             


Gln Thr Ala Ile Cys Asp Asn Gly Ala Gly Tyr Cys Ser Asn Pro Gly 
    130                 135                 140                 


Ile Pro Ile Gly Thr Arg Lys Val Gly Ser Gln Tyr Arg Leu Glu Asp 
145                 150                 155                 160 


Ser Val Thr Tyr His Cys Ser Arg Gly Leu Thr Leu Arg Gly Ser Gln 
                165                 170                 175     


Arg Arg Thr Cys Gln Glu Gly Gly Ser Trp Ser Gly Thr Glu Pro Ser 
            180                 185                 190         


Cys Gln Asp Ser Phe Met Tyr Asp Thr Pro Gln Glu Val Ala Glu Ala 
        195                 200                 205             


Phe Leu Ser Ser Leu Thr Glu Thr Ile Glu Gly Val Asp Ala Glu Asp 
    210                 215                 220                 


Gly His Gly Pro Gly Glu Gln Gln Lys Arg 
225                 230                 


<210>  1912
<211>  340
<212>  PRT
<213>  Homo Sapiens

<400>  1912

Leu Thr Leu Gly Asn Thr Thr Ser Ser Val Ile Leu Thr Asn Tyr Met 
1               5                   10                  15      


Asp Thr Gln Tyr Tyr Gly Glu Ile Gly Ile Gly Thr Pro Pro Gln Thr 
            20                  25                  30          


Phe Lys Val Val Phe Asp Thr Gly Ser Ser Asn Val Trp Val Pro Ser 
        35                  40                  45              


Ser Lys Cys Ser Arg Leu Tyr Thr Ala Cys Val Tyr His Lys Leu Phe 
    50                  55                  60                  


Asp Ala Ser Asp Ser Ser Ser Tyr Lys His Asn Gly Thr Glu Leu Thr 
65                  70                  75                  80  


Leu Arg Tyr Ser Thr Gly Thr Val Ser Gly Phe Leu Ser Gln Asp Ile 
                85                  90                  95      


Ile Thr Val Gly Gly Ile Thr Val Thr Gln Met Phe Gly Glu Val Thr 
            100                 105                 110         


Glu Met Pro Ala Leu Pro Phe Met Leu Ala Glu Phe Asp Gly Val Val 
        115                 120                 125             


Gly Met Gly Phe Ile Glu Gln Ala Ile Gly Arg Val Thr Pro Ile Phe 
    130                 135                 140                 


Asp Asn Ile Ile Ser Gln Gly Val Leu Lys Glu Asp Val Phe Ser Phe 
145                 150                 155                 160 


Tyr Tyr Asn Arg Asp Ser Glu Asn Ser Gln Ser Leu Gly Gly Gln Ile 
                165                 170                 175     


Val Leu Gly Gly Ser Asp Pro Gln His Tyr Glu Gly Asn Phe His Tyr 
            180                 185                 190         


Ile Asn Leu Ile Lys Thr Gly Val Trp Gln Ile Gln Met Lys Gly Val 
        195                 200                 205             


Ser Val Gly Ser Ser Thr Leu Leu Cys Glu Asp Gly Cys Leu Ala Leu 
    210                 215                 220                 


Val Asp Thr Gly Ala Ser Tyr Ile Ser Gly Ser Thr Ser Ser Ile Glu 
225                 230                 235                 240 


Lys Leu Met Glu Ala Leu Gly Ala Lys Lys Arg Leu Phe Asp Tyr Val 
                245                 250                 255     


Val Lys Cys Asn Glu Gly Pro Thr Leu Pro Asp Ile Ser Phe His Leu 
            260                 265                 270         


Gly Gly Lys Glu Tyr Thr Leu Thr Ser Ala Asp Tyr Val Phe Gln Glu 
        275                 280                 285             


Ser Tyr Ser Ser Lys Lys Leu Cys Thr Leu Ala Ile His Ala Met Asp 
    290                 295                 300                 


Ile Pro Pro Pro Thr Gly Pro Thr Trp Ala Leu Gly Ala Thr Phe Ile 
305                 310                 315                 320 


Arg Lys Phe Tyr Thr Glu Phe Asp Arg Arg Asn Asn Arg Ile Gly Phe 
                325                 330                 335     


Ala Leu Ala Arg 
            340 


<210>  1913
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  1913

Asp Ser Leu Gly Arg Glu Ala Lys Cys Tyr Asn Glu Leu Asn Gly Cys 
1               5                   10                  15      


Thr Lys Ile Tyr Asp Pro Val Cys Gly Thr Asp Gly Asn Thr Tyr Pro 
            20                  25                  30          


Asn Glu Cys Val Leu Cys Phe Glu Asn Arg Lys Arg Gln Thr Ser Ile 
        35                  40                  45              


Leu Ile Gln Lys Ser Gly Pro Cys 
    50                  55      


<210>  1914
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  1914

Glu Asp Pro Gln Gly Asp Ala Ala Gln Lys Thr Asp Thr Ser His His 
1               5                   10                  15      


Asp Gln Asp His Pro Thr Phe Asn Lys Ile Thr Pro Asn Leu Ala Glu 
            20                  25                  30          


Phe Ala Phe Ser Leu Tyr Arg Gln Leu Ala His Gln Ser Asn Ser Thr 
        35                  40                  45              


Asn Ile Phe Phe Ser Pro Val Ser Ile Ala Thr Ala Phe Ala Met Leu 
    50                  55                  60                  


Ser Leu Gly Thr Lys Ala Asp Thr His Asp Glu Ile Leu Glu Gly Leu 
65                  70                  75                  80  


Asn Phe Asn Leu Thr Glu Ile Pro Glu Ala Gln Ile His Glu Gly Phe 
                85                  90                  95      


Gln Glu Leu Leu Arg Thr Leu Asn Gln Pro Asp Ser Gln Leu Gln Leu 
            100                 105                 110         


Thr Thr Gly Asn Gly Leu Phe Leu Ser Glu Gly Leu Lys Leu Val Asp 
        115                 120                 125             


Lys Phe Leu Glu Asp Val Lys Lys Leu Tyr His Ser Glu Ala Phe Thr 
    130                 135                 140                 


Val Asn Phe Gly Asp Thr Glu Glu Ala Lys Lys Gln Ile Asn Asp Tyr 
145                 150                 155                 160 


Val Glu Lys Gly Thr Gln Gly Lys Ile Val Asp Leu Val Lys Glu Leu 
                165                 170                 175     


Asp Arg Asp Thr Val Phe Ala Leu Val Asn Tyr Ile Phe Phe Lys Gly 
            180                 185                 190         


Lys Trp Glu Arg Pro Phe Glu Val Lys Asp Thr Glu Glu Glu Asp Phe 
        195                 200                 205             


His Val Asp Gln Val Thr Thr Val Lys Val Pro Met Met Lys Arg Leu 
    210                 215                 220                 


Gly Met Phe Asn Ile Gln His Cys Lys Lys Leu Ser Ser Trp Val Leu 
225                 230                 235                 240 


Leu Met Lys Tyr Leu Gly Asn Ala Thr Ala Ile Phe Phe Leu Pro Asp 
                245                 250                 255     


Glu Gly Lys Leu Gln His Leu Glu Asn Glu Leu Thr His Asp Ile Ile 
            260                 265                 270         


Thr Lys Phe Leu Glu Asn Glu Asp Arg Arg Ser Ala Ser Leu His Leu 
        275                 280                 285             


Pro Lys Leu Ser Ile Thr Gly Thr Tyr Asp Leu Lys Ser Val Leu Gly 
    290                 295                 300                 


Gln Leu Gly Ile Thr Lys Val Phe Ser Asn Gly Ala Asp Leu Ser Gly 
305                 310                 315                 320 


Val Thr Glu Glu Ala Pro Leu Lys Leu Ser Lys Ala Val His Lys Ala 
                325                 330                 335     


Val Leu Thr Ile Asp Glu Lys Gly Thr Glu Ala Ala Gly Ala Met Phe 
            340                 345                 350         


Leu Glu Ala Ile Pro Met Ser Ile Pro Pro Glu Val Lys Phe Asn Lys 
        355                 360                 365             


Pro Phe Val Phe Leu Met Ile Asp Gln Asn Thr Lys Ser Pro Leu Phe 
    370                 375                 380                 


Met Gly Lys Val Val Asn Pro Thr Gln Lys 
385                 390                 


<210>  1915
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  1915

Asn Ser Pro Leu Asp Glu Glu Asn Leu Thr Gln Glu Asn Gln Asp Arg 
1               5                   10                  15      


Gly Thr His Val Asp Leu Gly Leu Ala Ser Ala Asn Val Asp Phe Ala 
            20                  25                  30          


Phe Ser Leu Tyr Lys Gln Leu Val Leu Lys Ala Pro Asp Lys Asn Val 
        35                  40                  45              


Ile Phe Ser Pro Leu Ser Ile Ser Thr Ala Leu Ala Phe Leu Ser Leu 
    50                  55                  60                  


Gly Ala His Asn Thr Thr Leu Thr Glu Ile Leu Lys Gly Leu Lys Phe 
65                  70                  75                  80  


Asn Leu Thr Glu Thr Ser Glu Ala Glu Ile His Gln Ser Phe Gln His 
                85                  90                  95      


Leu Leu Arg Thr Leu Asn Gln Ser Ser Asp Glu Leu Gln Leu Ser Met 
            100                 105                 110         


Gly Asn Ala Met Phe Val Lys Glu Gln Leu Ser Leu Leu Asp Arg Phe 
        115                 120                 125             


Thr Glu Asp Ala Lys Arg Leu Tyr Gly Ser Glu Ala Phe Ala Thr Asp 
    130                 135                 140                 


Phe Gln Asp Ser Ala Ala Ala Lys Lys Leu Ile Asn Asp Tyr Val Lys 
145                 150                 155                 160 


Asn Gly Thr Arg Gly Lys Ile Thr Asp Leu Ile Lys Asp Leu Asp Ser 
                165                 170                 175     


Gln Thr Met Met Val Leu Val Asn Tyr Ile Phe Phe Lys Ala Lys Trp 
            180                 185                 190         


Glu Met Pro Phe Asp Pro Gln Asp Thr His Gln Ser Arg Phe Tyr Leu 
        195                 200                 205             


Ser Lys Lys Lys Trp Val Met Val Pro Met Met Ser Leu His His Leu 
    210                 215                 220                 


Thr Ile Pro Tyr Phe Arg Asp Glu Glu Leu Ser Cys Thr Val Val Glu 
225                 230                 235                 240 


Leu Lys Tyr Thr Gly Asn Ala Ser Ala Leu Phe Ile Leu Pro Asp Gln 
                245                 250                 255     


Asp Lys Met Glu Glu Val Glu Ala Met Leu Leu Pro Glu Thr Leu Lys 
            260                 265                 270         


Arg Trp Arg Asp Ser Leu Glu Phe Arg Glu Ile Gly Glu Leu Tyr Leu 
        275                 280                 285             


Pro Lys Phe Ser Ile Ser Arg Asp Tyr Asn Leu Asn Asp Ile Leu Leu 
    290                 295                 300                 


Gln Leu Gly Ile Glu Glu Ala Phe Thr Ser Lys Ala Asp Leu Ser Gly 
305                 310                 315                 320 


Ile Thr Gly Ala Arg Asn Leu Ala Val Ser Gln Val Val His Lys Ala 
                325                 330                 335     


Val Leu Asp Val Phe Glu Glu Gly Thr Glu Ala Ser Ala Ala Thr Ala 
            340                 345                 350         


Val Lys Ile Thr Leu Leu Ser Ala Leu Val Glu Thr Arg Thr Ile Val 
        355                 360                 365             


Arg Phe Asn Arg Pro Phe Leu Met Ile Ile Val Pro Thr Asp Thr Gln 
    370                 375                 380                 


Asn Ile Phe Phe Met Ser Lys Val Thr Asn Pro Lys Gln Ala 
385                 390                 395             


<210>  1916
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  1916

Asp Arg Val Tyr Ile His Pro Phe His Leu Val Ile His Asn Glu Ser 
1               5                   10                  15      


Thr Cys Glu Gln Leu Ala Lys Ala Asn Ala Gly Lys Pro Lys Asp Pro 
            20                  25                  30          


Thr Phe Ile Pro Ala Pro Ile Gln Ala Lys Thr Ser Pro Val Asp Glu 
        35                  40                  45              


Lys Ala Leu Gln Asp Gln Leu Val Leu Val Ala Ala Lys Leu Asp Thr 
    50                  55                  60                  


Glu Asp Lys Leu Arg Ala Ala Met Val Gly Met Leu Ala Asn Phe Leu 
65                  70                  75                  80  


Gly Phe Arg Ile Tyr Gly Met His Ser Glu Leu Trp Gly Val Val His 
                85                  90                  95      


Gly Ala Thr Val Leu Ser Pro Thr Ala Val Phe Gly Thr Leu Ala Ser 
            100                 105                 110         


Leu Tyr Leu Gly Ala Leu Asp His Thr Ala Asp Arg Leu Gln Ala Ile 
        115                 120                 125             


Leu Gly Val Pro Trp Lys Asp Lys Asn Cys Thr Ser Arg Leu Asp Ala 
    130                 135                 140                 


His Lys Val Leu Ser Ala Leu Gln Ala Val Gln Gly Leu Leu Val Ala 
145                 150                 155                 160 


Gln Gly Arg Ala Asp Ser Gln Ala Gln Leu Leu Leu Ser Thr Val Val 
                165                 170                 175     


Gly Val Phe Thr Ala Pro Gly Leu His Leu Lys Gln Pro Phe Val Gln 
            180                 185                 190         


Gly Leu Ala Leu Tyr Thr Pro Val Val Leu Pro Arg Ser Leu Asp Phe 
        195                 200                 205             


Thr Glu Leu Asp Val Ala Ala Glu Lys Ile Asp Arg Phe Met Gln Ala 
    210                 215                 220                 


Val Thr Gly Trp Lys Thr Gly Cys Ser Leu Thr Gly Ala Ser Val Asp 
225                 230                 235                 240 


Ser Thr Leu Ala Phe Asn Thr Tyr Val His Phe Gln Gly Lys Met Lys 
                245                 250                 255     


Gly Phe Ser Leu Leu Ala Glu Pro Gln Glu Phe Trp Val Asp Asn Ser 
            260                 265                 270         


Thr Ser Val Ser Val Pro Met Leu Ser Gly Met Gly Thr Phe Gln His 
        275                 280                 285             


Trp Ser Asp Ile Gln Asp Asn Phe Ser Val Thr Gln Val Ser Phe Thr 
    290                 295                 300                 


Glu Ser Ala Cys Leu Leu Leu Ile Gln Pro His Tyr Ala Ser Asp Leu 
305                 310                 315                 320 


Asp Lys Val Glu Gly Leu Thr Phe Gln Gln Asn Ser Leu Asn Trp Met 
                325                 330                 335     


Lys Lys Leu Ser Pro Arg Thr Ile His Leu Thr Met Pro Gln Leu Val 
            340                 345                 350         


Leu Gln Gly Ser Tyr Asp Leu Gln Asp Leu Leu Ala Gln Ala Glu Leu 
        355                 360                 365             


Pro Ala Ile Leu His Thr Glu Leu Asn Leu Gln Lys Leu Ser Asn Asp 
    370                 375                 380                 


Arg Ile Arg Val Gly Glu Val Leu Asn Ser Ile Phe Phe Glu Leu Glu 
385                 390                 395                 400 


Ala Asp Glu Arg Glu Pro Thr Glu Ser Thr Gln Gln Leu Asn Lys Pro 
                405                 410                 415     


Glu Val Leu Glu Val Thr Leu Asn Arg Pro Phe Leu Phe Ala Val Tyr 
            420                 425                 430         


Asp Gln Ser Ala Thr Ala Leu His Phe Leu Gly Arg Val Ala Asn Pro 
        435                 440                 445             


Leu Ser Thr Ala 
    450         


<210>  1917
<211>  184
<212>  PRT
<213>  Homo Sapiens

<400>  1917

Cys Thr Cys Val Pro Pro His Pro Gln Thr Ala Phe Cys Asn Ser Asp 
1               5                   10                  15      


Leu Val Ile Arg Ala Lys Phe Val Gly Thr Pro Glu Val Asn Gln Thr 
            20                  25                  30          


Thr Leu Tyr Gln Arg Tyr Glu Ile Lys Met Thr Lys Met Tyr Lys Gly 
        35                  40                  45              


Phe Gln Ala Leu Gly Asp Ala Ala Asp Ile Arg Phe Val Tyr Thr Pro 
    50                  55                  60                  


Ala Met Glu Ser Val Cys Gly Tyr Phe His Arg Ser His Asn Arg Ser 
65                  70                  75                  80  


Glu Glu Phe Leu Ile Ala Gly Lys Leu Gln Asp Gly Leu Leu His Ile 
                85                  90                  95      


Thr Thr Cys Ser Phe Val Ala Pro Trp Asn Ser Leu Ser Leu Ala Gln 
            100                 105                 110         


Arg Arg Gly Phe Thr Lys Thr Tyr Thr Val Gly Cys Glu Glu Cys Thr 
        115                 120                 125             


Val Phe Pro Cys Leu Ser Ile Pro Cys Lys Leu Gln Ser Gly Thr His 
    130                 135                 140                 


Cys Leu Trp Thr Asp Gln Leu Leu Gln Gly Ser Glu Lys Gly Phe Gln 
145                 150                 155                 160 


Ser Arg His Leu Ala Cys Leu Pro Arg Glu Pro Gly Leu Cys Thr Trp 
                165                 170                 175     


Gln Ser Leu Arg Ser Gln Ile Ala 
            180                 


<210>  1918
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  1918

Ser Ser Pro Gly Lys Pro Pro Arg Leu Val Gly Gly Pro Met Asp Ala 
1               5                   10                  15      


Ser Val Glu Glu Glu Gly Val Arg Arg Ala Leu Asp Phe Ala Val Gly 
            20                  25                  30          


Glu Tyr Asn Lys Ala Ser Asn Asp Met Tyr His Ser Arg Ala Leu Gln 
        35                  40                  45              


Val Val Arg Ala Arg Lys Gln Ile Val Ala Gly Val Asn Tyr Phe Leu 
    50                  55                  60                  


Asp Val Glu Leu Gly Arg Thr Thr Cys Thr Lys Thr Gln Pro Asn Leu 
65                  70                  75                  80  


Asp Asn Cys Pro Phe His Asp Gln Pro His Leu Lys Arg Lys Ala Phe 
                85                  90                  95      


Cys Ser Phe Gln Ile Tyr Ala Val Pro Trp Gln Gly Thr Met Thr Leu 
            100                 105                 110         


Ser Lys Ser Thr Cys Gln Asp Ala 
        115                 120 


<210>  1919
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1919

Ser Ser Ser Lys Glu Glu Asn Arg Ile Ile Pro Gly Gly Ile Tyr Asp 
1               5                   10                  15      


Ala Asp Leu Asn Asp Glu Trp Val Gln Arg Ala Leu His Phe Ala Ile 
            20                  25                  30          


Ser Glu Tyr Asn Lys Ala Thr Glu Asp Glu Tyr Tyr Arg Arg Pro Leu 
        35                  40                  45              


Gln Val Leu Arg Ala Arg Glu Gln Thr Phe Gly Gly Val Asn Tyr Phe 
    50                  55                  60                  


Phe Asp Val Glu Val Gly Arg Thr Ile Cys Thr Lys Ser Gln Pro Asn 
65                  70                  75                  80  


Leu Asp Thr Cys Ala Phe His Glu Gln Pro Glu Leu Gln Lys Lys Gln 
                85                  90                  95      


Leu Cys Ser Phe Glu Ile Tyr Glu Val Pro Trp Glu Asp Arg Met Ser 
            100                 105                 110         


Leu Val Asn Ser Arg Cys Gln Glu Ala 
        115                 120     


<210>  1920
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  1920

Trp Ser Pro Lys Glu Glu Asp Arg Ile Ile Pro Gly Gly Ile Tyr Asn 
1               5                   10                  15      


Ala Asp Leu Asn Asp Glu Trp Val Gln Arg Ala Leu His Phe Ala Ile 
            20                  25                  30          


Ser Glu Tyr Asn Lys Ala Thr Lys Asp Asp Tyr Tyr Arg Arg Pro Leu 
        35                  40                  45              


Arg Val Leu Arg Ala Arg Gln Gln Thr Val Gly Gly Val Asn Tyr Phe 
    50                  55                  60                  


Phe Asp Val Glu Val Gly Arg Thr Ile Cys Thr Lys Ser Gln Pro Asn 
65                  70                  75                  80  


Leu Asp Thr Cys Ala Phe His Glu Gln Pro Glu Leu Gln Lys Lys Gln 
                85                  90                  95      


Leu Cys Ser Phe Glu Ile Tyr Glu Val Pro Trp Glu Asn Arg Arg Ser 
            100                 105                 110         


Leu Val Lys Ser Arg Cys Gln Glu Ser 
        115                 120     


<210>  1921
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1921

Gln His Trp Ser Tyr Gly Leu Arg Pro Gly Gly Lys Arg Asp Ala Glu 
1               5                   10                  15      


Asn Leu Ile Asp Ser Phe Gln Glu Ile Val Lys Glu Val Gly Gln Leu 
            20                  25                  30          


Ala Glu Thr Gln Arg Phe Glu Cys Thr Thr His Gln Pro Arg Ser Pro 
        35                  40                  45              


Leu Arg Asp Leu Lys Gly Ala Leu Glu Ser Leu Ile Glu Glu Glu Thr 
    50                  55                  60                  


Gly Gln Lys Lys Ile 
65                  


<210>  1922
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  1922

Ala Ala Pro Asp Leu Asp Val Arg Lys Cys Leu Pro Cys Gly Pro Gly 
1               5                   10                  15      


Gly Lys Gly Arg Cys Phe Gly Pro Asn Ile Cys Cys Ala Glu Glu Leu 
            20                  25                  30          


Gly Cys Phe Val Gly Thr Ala Glu Ala Leu Arg Cys Gln Glu Glu Asn 
        35                  40                  45              


Tyr Leu Pro Ser Pro Cys Gln Ser Gly Gln Lys Ala Cys Gly Ser Gly 
    50                  55                  60                  


Gly Arg Cys Ala Val Leu Gly Leu Cys Cys Ser Pro Asp Gly Cys His 
65                  70                  75                  80  


Ala Asp Pro Ala Cys Asp Ala Glu Ala Thr Phe Ser Gln Arg 
                85                  90                  


<210>  1923
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1923

Ala Met Ser Asp Leu Glu Leu Arg Gln Cys Leu Pro Cys Gly Pro Gly 
1               5                   10                  15      


Gly Lys Gly Arg Cys Phe Gly Pro Ser Ile Cys Cys Ala Asp Glu Leu 
            20                  25                  30          


Gly Cys Phe Val Gly Thr Ala Glu Ala Leu Arg Cys Gln Glu Glu Asn 
        35                  40                  45              


Tyr Leu Pro Ser Pro Cys Gln Ser Gly Gln Lys Ala Cys Gly Ser Gly 
    50                  55                  60                  


Gly Arg Cys Ala Ala Phe Gly Val Cys Cys Asn Asp Glu Ser Cys Val 
65                  70                  75                  80  


Thr Glu Pro Glu Cys Arg Glu Gly Phe His Arg Arg Ala 
                85                  90              


<210>  1924
<211>  89
<212>  PRT
<213>  Homo Sapiens

<400>  1924

Glu Leu Thr Gly Gln Arg Leu Arg Glu Gly Asp Gly Pro Asp Gly Pro 
1               5                   10                  15      


Ala Asp Asp Gly Ala Gly Ala Gln Ala Asp Leu Glu His Ser Leu Leu 
            20                  25                  30          


Val Ala Ala Glu Lys Lys Asp Glu Gly Pro Tyr Arg Met Glu His Phe 
        35                  40                  45              


Arg Trp Gly Ser Pro Pro Lys Asp Lys Arg Tyr Gly Gly Phe Met Thr 
    50                  55                  60                  


Ser Glu Lys Ser Gln Thr Pro Leu Val Thr Leu Phe Lys Asn Ala Ile 
65                  70                  75                  80  


Ile Lys Asn Ala Tyr Lys Lys Gly Glu 
                85                  


<210>  1925
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  1925

Phe Cys Ile Pro Thr Glu Tyr Thr Met His Ile Glu Arg Arg Glu Cys 
1               5                   10                  15      


Ala Tyr Cys Leu Thr Ile Asn Thr Thr Ile Cys Ala Gly Tyr Cys Met 
            20                  25                  30          


Thr Arg Asp Ile Asn Gly Lys Leu Phe Leu Pro Lys Tyr Ala Leu Ser 
        35                  40                  45              


Gln Asp Val Cys Thr Tyr Arg Asp Phe Ile Tyr Arg Thr Val Glu Ile 
    50                  55                  60                  


Pro Gly Cys Pro Leu His Val Ala Pro Tyr Phe Ser Tyr Pro Val Ala 
65                  70                  75                  80  


Leu Ser Cys Lys Cys Gly Lys Cys Asn Thr Asp Tyr Ser Asp Cys Ile 
                85                  90                  95      


His Glu Ala Ile Lys Thr Asn Tyr Cys Thr Lys Pro Gln Lys Ser Tyr 
            100                 105                 110         


<210>  1926
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  1926

Asn Ser Cys Glu Leu Thr Asn Ile Thr Ile Ala Ile Glu Lys Glu Glu 
1               5                   10                  15      


Cys Arg Phe Cys Ile Ser Ile Asn Thr Thr Trp Cys Ala Gly Tyr Cys 
            20                  25                  30          


Tyr Thr Arg Asp Leu Val Tyr Lys Asp Pro Ala Arg Pro Lys Ile Gln 
        35                  40                  45              


Lys Thr Cys Thr Phe Lys Glu Leu Val Tyr Glu Thr Val Arg Val Pro 
    50                  55                  60                  


Gly Cys Ala His His Ala Asp Ser Leu Tyr Thr Tyr Pro Val Ala Thr 
65                  70                  75                  80  


Gln Cys His Cys Gly Lys Cys Asp Ser Asp Ser Thr Asp Cys Thr Val 
                85                  90                  95      


Arg Gly Leu Gly Pro Ser Tyr Cys Ser Phe Gly Glu Met Lys Glu 
            100                 105                 110     


<210>  1927
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  1927

Leu Pro Ile Cys Pro Gly Gly Ala Ala Arg Cys Gln Val Thr Leu Arg 
1               5                   10                  15      


Asp Leu Phe Asp Arg Ala Val Val Leu Ser His Tyr Ile His Asn Leu 
            20                  25                  30          


Ser Ser Glu Met Phe Ser Glu Phe Asp Lys Arg Tyr Thr His Gly Arg 
        35                  40                  45              


Gly Phe Ile Thr Lys Ala Ile Asn Ser Cys His Thr Ser Ser Leu Ala 
    50                  55                  60                  


Thr Pro Glu Asp Lys Glu Gln Ala Gln Gln Met Asn Gln Lys Asp Phe 
65                  70                  75                  80  


Leu Ser Leu Ile Val Ser Ile Leu Arg Ser Trp Asn Glu Pro Leu Tyr 
                85                  90                  95      


His Leu Val Thr Glu Val Arg Gly Met Gln Glu Ala Pro Glu Ala Ile 
            100                 105                 110         


Leu Ser Lys Ala Val Glu Ile Glu Glu Gln Thr Lys Arg Leu Leu Glu 
        115                 120                 125             


Gly Met Glu Leu Ile Val Ser Gln Val His Pro Glu Thr Lys Glu Asn 
    130                 135                 140                 


Glu Ile Tyr Pro Val Trp Ser Gly Leu Pro Ser Leu Gln Met Ala Asp 
145                 150                 155                 160 


Glu Glu Ser Arg Leu Ser Ala Tyr Tyr Asn Leu Leu His Cys Leu Arg 
                165                 170                 175     


Arg Asp Ser His Lys Ile Asp Asn Tyr Leu Lys Leu Leu Lys Cys Arg 
            180                 185                 190         


Ile Ile His Asn Asn Asn Cys 
        195                 


<210>  1928
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  1928

Phe Pro Thr Ile Pro Leu Ser Arg Leu Phe Asp Asn Ala Met Leu Arg 
1               5                   10                  15      


Ala Arg Arg Leu Tyr Gln Leu Ala Tyr Asp Thr Tyr Gln Glu Phe Glu 
            20                  25                  30          


Glu Ala Tyr Ile Leu Lys Glu Gln Lys Tyr Ser Phe Leu Gln Asn Pro 
        35                  40                  45              


Gln Thr Ser Leu Cys Phe Ser Glu Ser Ile Pro Thr Pro Ser Asn Arg 
    50                  55                  60                  


Val Lys Thr Gln Gln Lys Ser Asn Leu Glu Leu Leu Arg Ile Ser Leu 
65                  70                  75                  80  


Leu Leu Ile Gln Ser Trp Leu Glu Pro Val Gln Leu Leu Arg Ser Val 
                85                  90                  95      


Phe Ala Asn Ser Leu Val Tyr Gly Ala Ser Asp Ser Asn Val Tyr Arg 
            100                 105                 110         


His Leu Lys Asp Leu Glu Glu Gly Ile Gln Thr Leu Met Trp Arg Leu 
        115                 120                 125             


Glu Asp Gly Ser Pro Arg Thr Gly Gln Ile Phe Asn Gln Ser Tyr Ser 
    130                 135                 140                 


Lys Phe Asp Thr Lys Ser His Asn Asp Asp Ala Leu Leu Lys Asn Tyr 
145                 150                 155                 160 


Gly Leu Leu Tyr Cys Phe Arg Lys Asp Met Asp Lys Val Glu Thr Phe 
                165                 170                 175     


Leu Arg Ile Val Gln Cys Arg Ser Val Glu Gly Ser Cys Gly Phe 
            180                 185                 190     


<210>  1929
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  1929

Arg Ser Leu Gln Asp Thr Glu Glu Lys Ser Arg Ser Phe Ser Ala Ser 
1               5                   10                  15      


Gln Ala Asp Pro Leu Ser Asp Pro Asp Gln Met Asn Glu Asp Lys Arg 
            20                  25                  30          


His Ser Gln Gly Thr Phe Thr Ser Asp Tyr Ser Lys Tyr Leu Asp Ser 
        35                  40                  45              


Arg Arg Ala Gln Asp Phe Val Gln Trp Leu Met Asn Thr Lys Arg Asn 
    50                  55                  60                  


Arg Asn Asn Ile Ala 
65                  


<210>  1930
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  1930

Ser Trp Lys Pro Arg Ser Gln Gln Pro Asp Ala Pro Leu Gly Thr Gly 
1               5                   10                  15      


Ala Asn Arg Asp Leu Glu Leu Pro Trp Leu Glu Gln Gln Gly Pro Ala 
            20                  25                  30          


Ser His His Arg Arg Gln Leu Gly Pro Gln Gly Pro Pro His Leu Val 
        35                  40                  45              


Ala Asp Pro Ser Lys Lys Gln Gly Pro Trp Leu Glu Glu Glu Glu Glu 
    50                  55                  60                  


Ala Tyr Gly Trp Met Asp Phe 
65                  70      


<210>  1931
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  1931

Asp Glu Pro Pro Gln Ser Pro Trp Asp Arg Val Lys Asp Leu Ala Thr 
1               5                   10                  15      


Val Tyr Val Asp Val Leu Lys Asp Ser Gly Arg Asp Tyr Val Ser Gln 
            20                  25                  30          


Phe Glu Gly Ser Ala Leu Gly Lys Gln Leu Asn Leu Lys Leu Leu Asp 
        35                  40                  45              


Asn Trp Asp Ser Val Thr Ser Thr Phe Ser Lys Leu Arg Glu Gln Leu 
    50                  55                  60                  


Gly Pro Val Thr Gln Glu Phe Trp Asp Asn Leu Glu Lys Glu Thr Glu 
65                  70                  75                  80  


Gly Leu Arg Gln Glu Met Ser Lys Asp Leu Glu Glu Val Lys Ala Lys 
                85                  90                  95      


Val Gln Pro Tyr Leu Asp Asp Phe Gln Lys Lys Trp Gln Glu Glu Met 
            100                 105                 110         


Glu Leu Tyr Arg Gln Lys Val Glu Pro Leu Arg Ala Glu Leu Gln Glu 
        115                 120                 125             


Gly Ala Arg Gln Lys Leu His Glu Leu Gln Glu Lys Leu Ser Pro Leu 
    130                 135                 140                 


Gly Glu Glu Met Arg Asp Arg Ala Arg Ala His Val Asp Ala Leu Arg 
145                 150                 155                 160 


Thr His Leu Ala Pro Tyr Ser Asp Glu Leu Arg Gln Arg Leu Ala Ala 
                165                 170                 175     


Arg Leu Glu Ala Leu Lys Glu Asn Gly Gly Ala Arg Leu Ala Glu Tyr 
            180                 185                 190         


His Ala Lys Ala Thr Glu His Leu Ser Thr Leu Ser Glu Lys Ala Lys 
        195                 200                 205             


Pro Ala Leu Glu Asp Leu Arg Gln Gly Leu Leu Pro Val Leu Glu Ser 
    210                 215                 220                 


Phe Lys Val Ser Phe Leu Ser Ala Leu Glu Glu Tyr Thr Lys Lys Leu 
225                 230                 235                 240 


Asn Thr Gln 
            


<210>  1932
<211>  299
<212>  PRT
<213>  Homo Sapiens

<400>  1932

Lys Val Glu Gln Ala Val Glu Thr Glu Pro Glu Pro Glu Leu Arg Gln 
1               5                   10                  15      


Gln Thr Glu Trp Gln Ser Gly Gln Arg Trp Glu Leu Ala Leu Gly Arg 
            20                  25                  30          


Phe Trp Asp Tyr Leu Arg Trp Val Gln Thr Leu Ser Glu Gln Val Gln 
        35                  40                  45              


Glu Glu Leu Leu Ser Ser Gln Val Thr Gln Glu Leu Arg Ala Leu Met 
    50                  55                  60                  


Asp Glu Thr Met Lys Glu Leu Lys Ala Tyr Lys Ser Glu Leu Glu Glu 
65                  70                  75                  80  


Gln Leu Thr Pro Val Ala Glu Glu Thr Arg Ala Arg Leu Ser Lys Glu 
                85                  90                  95      


Leu Gln Ala Ala Gln Ala Arg Leu Gly Ala Asp Met Glu Asp Val Cys 
            100                 105                 110         


Gly Arg Leu Val Gln Tyr Arg Gly Glu Val Gln Ala Met Leu Gly Gln 
        115                 120                 125             


Ser Thr Glu Glu Leu Arg Val Arg Leu Ala Ser His Leu Arg Lys Leu 
    130                 135                 140                 


Arg Lys Arg Leu Leu Arg Asp Ala Asp Asp Leu Gln Lys Arg Leu Ala 
145                 150                 155                 160 


Val Tyr Gln Ala Gly Ala Arg Glu Gly Ala Glu Arg Gly Leu Ser Ala 
                165                 170                 175     


Ile Arg Glu Arg Leu Gly Pro Leu Val Glu Gln Gly Arg Val Arg Ala 
            180                 185                 190         


Ala Thr Val Gly Ser Leu Ala Gly Gln Pro Leu Gln Glu Arg Ala Gln 
        195                 200                 205             


Ala Trp Gly Glu Arg Leu Arg Ala Arg Met Glu Glu Met Gly Ser Arg 
    210                 215                 220                 


Thr Arg Asp Arg Leu Asp Glu Val Lys Glu Gln Val Ala Glu Val Arg 
225                 230                 235                 240 


Ala Lys Leu Glu Glu Gln Ala Gln Gln Ile Arg Leu Gln Ala Glu Ala 
                245                 250                 255     


Phe Gln Ala Arg Leu Lys Ser Trp Phe Glu Pro Leu Val Glu Asp Met 
            260                 265                 270         


Gln Arg Gln Trp Ala Gly Leu Val Glu Lys Val Gln Ala Ala Val Gly 
        275                 280                 285             


Thr Ser Ala Ala Pro Val Pro Ser Asp Asn His 
    290                 295                 


<210>  1933
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  1933

Gln Ala Lys Glu Pro Cys Val Glu Ser Leu Val Ser Gln Tyr Phe Gln 
1               5                   10                  15      


Thr Val Thr Asp Tyr Gly Lys Asp Leu Met Glu Lys Val Lys Ser Pro 
            20                  25                  30          


Glu Leu Gln Ala Glu Ala Lys Ser Tyr Phe Glu Lys Ser Lys Glu Gln 
        35                  40                  45              


Leu Thr Pro Leu Ile Lys Lys Ala Gly Thr Glu Leu Val Asn Phe Leu 
    50                  55                  60                  


Ser Tyr Phe Val Glu Leu Gly Thr Gln Pro Ala Thr Gln 
65                  70                  75          


<210>  1934
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  1934

Thr Pro Asp Val Ser Ser Ala Leu Asp Lys Leu Lys Glu Phe Gly Asn 
1               5                   10                  15      


Thr Leu Glu Asp Lys Ala Arg Glu Leu Ile Ser Arg Ile Lys Gln Ser 
            20                  25                  30          


Glu Leu Ser Ala Lys Met Arg Glu Trp Phe Ser Glu Thr Phe Gln Lys 
        35                  40                  45              


Val Lys Glu Lys Leu Lys Ile Asp Ser 
    50                  55          


<210>  1935
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  1935

Asp Glu Met Pro Ser Pro Thr Leu Leu Thr Gln Val Lys Glu Ser Leu 
1               5                   10                  15      


Ser Ser Tyr Trp Glu Ser Ala Lys Thr Ala Ala Gln Asn Leu Tyr Glu 
            20                  25                  30          


Lys Thr Tyr Leu Pro Ala Val Asp Glu Lys Leu Arg Asp Leu Tyr Ser 
        35                  40                  45              


Lys Ser Thr Ala Ala Met Ser Thr Tyr Thr Gly Ile Phe Thr Asp Gln 
    50                  55                  60                  


Val Leu Ser Val Leu Lys Gly Glu Glu 
65                  70              


<210>  1936
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  1936

Ser Glu Ala Glu Asp Ala Ser Leu Leu Ser Phe Met Gln Gly Tyr Met 
1               5                   10                  15      


Lys His Ala Thr Lys Thr Ala Lys Asp Ala Leu Ser Ser Val Gln Glu 
            20                  25                  30          


Ser Gln Val Ala Gln Gln Ala Arg Gly Trp Val Thr Asp Gly Phe Ser 
        35                  40                  45              


Ser Leu Lys Asp Tyr Trp Ser Thr Val Lys Asp Lys Phe Ser Glu Phe 
    50                  55                  60                  


Trp Asp Leu Asp Pro Glu Val Arg Pro Thr Ser Ala Val Ala Ala 
65                  70                  75                  


<210>  1937
<211>  447
<212>  PRT
<213>  Homo Sapiens

<400>  1937

Gly His Arg Pro Leu Asp Lys Lys Arg Glu Glu Ala Pro Ser Leu Arg 
1               5                   10                  15      


Pro Ala Pro Pro Pro Ile Ser Gly Gly Gly Tyr Arg Ala Arg Pro Ala 
            20                  25                  30          


Lys Ala Ala Ala Thr Gln Lys Lys Val Glu Arg Lys Ala Pro Asp Ala 
        35                  40                  45              


Gly Gly Cys Leu His Ala Asp Pro Asp Leu Gly Val Leu Cys Pro Thr 
    50                  55                  60                  


Gly Cys Gln Leu Gln Glu Ala Leu Leu Gln Gln Glu Arg Pro Ile Arg 
65                  70                  75                  80  


Asn Ser Val Asp Glu Leu Asn Asn Asn Val Glu Ala Val Ser Gln Thr 
                85                  90                  95      


Ser Ser Ser Ser Phe Gln Tyr Met Tyr Leu Leu Lys Asp Leu Trp Gln 
            100                 105                 110         


Lys Arg Gln Lys Gln Val Lys Asp Asn Glu Asn Val Val Asn Glu Tyr 
        115                 120                 125             


Ser Ser Glu Leu Glu Lys His Gln Leu Tyr Ile Asp Glu Thr Val Asn 
    130                 135                 140                 


Ser Asn Ile Pro Thr Asn Leu Arg Val Leu Arg Ser Ile Leu Glu Asn 
145                 150                 155                 160 


Leu Arg Ser Lys Ile Gln Lys Leu Glu Ser Asp Val Ser Ala Gln Met 
                165                 170                 175     


Glu Tyr Cys Arg Thr Pro Cys Thr Val Ser Cys Asn Ile Pro Val Val 
            180                 185                 190         


Ser Gly Lys Glu Cys Glu Glu Ile Ile Arg Lys Gly Gly Glu Thr Ser 
        195                 200                 205             


Glu Met Tyr Leu Ile Gln Pro Asp Ser Ser Val Lys Pro Tyr Arg Val 
    210                 215                 220                 


Tyr Cys Asp Met Asn Thr Glu Asn Gly Gly Trp Thr Val Ile Gln Asn 
225                 230                 235                 240 


Arg Gln Asp Gly Ser Val Asp Phe Gly Arg Lys Trp Asp Pro Tyr Lys 
                245                 250                 255     


Gln Gly Phe Gly Asn Val Ala Thr Asn Thr Asp Gly Lys Asn Tyr Cys 
            260                 265                 270         


Gly Leu Pro Gly Glu Tyr Trp Leu Gly Asn Asp Lys Ile Ser Gln Leu 
        275                 280                 285             


Thr Arg Met Gly Pro Thr Glu Leu Leu Ile Glu Met Glu Asp Trp Lys 
    290                 295                 300                 


Gly Asp Lys Val Lys Ala His Tyr Gly Gly Phe Thr Val Gln Asn Glu 
305                 310                 315                 320 


Ala Asn Lys Tyr Gln Ile Ser Val Asn Lys Tyr Arg Gly Thr Ala Gly 
                325                 330                 335     


Asn Ala Leu Met Asp Gly Ala Ser Gln Leu Met Gly Glu Asn Arg Thr 
            340                 345                 350         


Met Thr Ile His Asn Gly Met Phe Phe Ser Thr Tyr Asp Arg Asp Asn 
        355                 360                 365             


Asp Gly Trp Leu Thr Ser Asp Pro Arg Lys Gln Cys Ser Lys Glu Asp 
    370                 375                 380                 


Gly Gly Gly Trp Trp Tyr Asn Arg Cys His Ala Ala Asn Pro Asn Gly 
385                 390                 395                 400 


Arg Tyr Tyr Trp Gly Gly Gln Tyr Thr Trp Asp Met Ala Lys His Gly 
                405                 410                 415     


Thr Asp Asp Gly Val Val Trp Met Asn Trp Lys Gly Ser Trp Tyr Ser 
            420                 425                 430         


Met Arg Lys Met Ser Met Lys Ile Arg Pro Phe Phe Pro Gln Gln 
        435                 440                 445         


<210>  1938
<211>  411
<212>  PRT
<213>  Homo Sapiens

<400>  1938

Tyr Val Ala Thr Arg Asp Asn Cys Cys Ile Leu Asp Glu Arg Phe Gly 
1               5                   10                  15      


Ser Tyr Cys Pro Thr Thr Cys Gly Ile Ala Asp Phe Leu Ser Thr Tyr 
            20                  25                  30          


Gln Thr Lys Val Asp Lys Asp Leu Gln Ser Leu Glu Asp Ile Leu His 
        35                  40                  45              


Gln Val Glu Asn Lys Thr Ser Glu Val Lys Gln Leu Ile Lys Ala Ile 
    50                  55                  60                  


Gln Leu Thr Tyr Asn Pro Asp Glu Ser Ser Lys Pro Asn Met Ile Asp 
65                  70                  75                  80  


Ala Ala Thr Leu Lys Ser Arg Lys Met Leu Glu Glu Ile Met Lys Tyr 
                85                  90                  95      


Glu Ala Ser Ile Leu Thr His Asp Ser Ser Ile Arg Tyr Leu Gln Glu 
            100                 105                 110         


Ile Tyr Asn Ser Asn Asn Gln Lys Ile Val Asn Leu Lys Glu Lys Val 
        115                 120                 125             


Ala Gln Leu Glu Ala Gln Cys Gln Glu Pro Cys Lys Asp Thr Val Gln 
    130                 135                 140                 


Ile His Asp Ile Thr Gly Lys Asp Cys Gln Asp Ile Ala Asn Lys Gly 
145                 150                 155                 160 


Ala Lys Gln Ser Gly Leu Tyr Phe Ile Lys Pro Leu Lys Ala Asn Gln 
                165                 170                 175     


Gln Phe Leu Val Tyr Cys Glu Ile Asp Gly Ser Gly Asn Gly Trp Thr 
            180                 185                 190         


Val Phe Gln Lys Arg Leu Asp Gly Ser Val Asp Phe Lys Lys Asn Trp 
        195                 200                 205             


Ile Gln Tyr Lys Glu Gly Phe Gly His Leu Ser Pro Thr Gly Thr Thr 
    210                 215                 220                 


Glu Phe Trp Leu Gly Asn Glu Lys Ile His Leu Ile Ser Thr Gln Ser 
225                 230                 235                 240 


Ala Ile Pro Tyr Ala Leu Arg Val Glu Leu Glu Asp Trp Asn Gly Arg 
                245                 250                 255     


Thr Ser Thr Ala Asp Tyr Ala Met Phe Lys Val Gly Pro Glu Ala Asp 
            260                 265                 270         


Lys Tyr Arg Leu Thr Tyr Ala Tyr Phe Ala Gly Gly Asp Ala Gly Asp 
        275                 280                 285             


Ala Phe Asp Gly Phe Asp Phe Gly Asp Asp Pro Ser Asp Lys Phe Phe 
    290                 295                 300                 


Thr Ser His Asn Gly Met Gln Phe Ser Thr Trp Asp Asn Asp Asn Asp 
305                 310                 315                 320 


Lys Phe Glu Gly Asn Cys Ala Glu Gln Asp Gly Ser Gly Trp Trp Met 
                325                 330                 335     


Asn Lys Cys His Ala Gly His Leu Asn Gly Val Tyr Tyr Gln Gly Gly 
            340                 345                 350         


Thr Tyr Ser Lys Ala Ser Thr Pro Asn Gly Tyr Asp Asn Gly Ile Ile 
        355                 360                 365             


Trp Ala Thr Trp Lys Thr Arg Trp Tyr Ser Met Lys Lys Thr Thr Met 
    370                 375                 380                 


Lys Ile Ile Pro Phe Asn Arg Leu Thr Ile Gly Glu Gly Gln Gln His 
385                 390                 395                 400 


His Leu Gly Gly Ala Lys Gln Ala Gly Asp Val 
                405                 410     


<210>  1939
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  1939

Leu Ser Thr Thr Glu Val Ala Met His Thr Ser Thr Ser Ser Ser Val 
1               5                   10                  15      


Thr Lys Ser Tyr Ile Ser Ser Gln Thr Asn Asp Thr His Lys Arg Asp 
            20                  25                  30          


Thr Tyr Ala Ala Thr Pro Arg Ala His Glu Val Ser Glu Ile Ser Val 
        35                  40                  45              


Arg Thr Val Tyr Pro Pro Glu Glu Glu Thr Gly Glu Arg Val Gln Leu 
    50                  55                  60                  


Ala His His Phe Ser Glu Pro Glu 
65                  70          


<210>  1940
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  1940

Gln Thr Asp Met Ser Arg Lys Ala Phe Val Phe Pro Lys Glu Ser Asp 
1               5                   10                  15      


Thr Ser Tyr Val Ser Leu Lys Ala Pro Leu Thr Lys Pro Leu Lys Ala 
            20                  25                  30          


Phe Thr Val Cys Leu His Phe Tyr Thr Glu Leu Ser Ser Thr Arg Gly 
        35                  40                  45              


Tyr Ser Ile Phe Ser Tyr Ala Thr Lys Arg Gln Asp Asn Glu Ile Leu 
    50                  55                  60                  


Ile Phe Trp Ser Lys Asp Ile Gly Tyr Ser Phe Thr Val Gly Gly Ser 
65                  70                  75                  80  


Glu Ile Leu Phe Glu Val Pro Glu Val Thr Val Ala Pro Val His Ile 
                85                  90                  95      


Cys Thr Ser Trp Glu Ser Ala Ser Gly Ile Val Glu Phe Trp Val Asp 
            100                 105                 110         


Gly Lys Pro Arg Val Arg Lys Ser Leu Lys Lys Gly Tyr Thr Val Gly 
        115                 120                 125             


Ala Glu Ala Ser Ile Ile Leu Gly Gln Glu Gln Asp Ser Phe Gly Gly 
    130                 135                 140                 


Asn Phe Glu Gly Ser Gln Ser Leu Val Gly Asp Ile Gly Asn Val Asn 
145                 150                 155                 160 


Met Trp Asp Phe Val Leu Ser Pro Asp Glu Ile Asn Thr Ile Tyr Leu 
                165                 170                 175     


Gly Gly Pro Phe Ser Pro Asn Val Leu Asn Trp Arg Ala Leu Lys Tyr 
            180                 185                 190         


Glu Val Gln Gly Glu Val Phe Thr Lys Pro Gln Leu Trp Pro 
        195                 200                 205     


<210>  1941
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  1941

His Thr Asp Leu Ser Gly Lys Val Phe Val Phe Pro Arg Glu Ser Val 
1               5                   10                  15      


Thr Asp His Val Asn Leu Ile Thr Pro Leu Glu Lys Pro Leu Gln Asn 
            20                  25                  30          


Phe Thr Leu Cys Phe Arg Ala Tyr Ser Asp Leu Ser Arg Ala Tyr Ser 
        35                  40                  45              


Leu Phe Ser Tyr Asn Thr Gln Gly Arg Asp Asn Glu Leu Leu Val Tyr 
    50                  55                  60                  


Lys Glu Arg Val Gly Glu Tyr Ser Leu Tyr Ile Gly Arg His Lys Val 
65                  70                  75                  80  


Thr Ser Lys Val Ile Glu Lys Phe Pro Ala Pro Val His Ile Cys Val 
                85                  90                  95      


Ser Trp Glu Ser Ser Ser Gly Ile Ala Glu Phe Trp Ile Asn Gly Thr 
            100                 105                 110         


Pro Leu Val Lys Lys Gly Leu Arg Gln Gly Tyr Phe Val Glu Ala Gln 
        115                 120                 125             


Pro Lys Ile Val Leu Gly Gln Glu Gln Asp Ser Tyr Gly Gly Lys Phe 
    130                 135                 140                 


Asp Arg Ser Gln Ser Phe Val Gly Glu Ile Gly Asp Leu Tyr Met Trp 
145                 150                 155                 160 


Asp Ser Val Leu Pro Pro Glu Asn Ile Leu Ser Ala Tyr Gln Gly Thr 
                165                 170                 175     


Pro Leu Pro Ala Asn Ile Leu Asp Trp Gln Ala Leu Asn Tyr Glu Ile 
            180                 185                 190         


Arg Gly Tyr Val Ile Ile Lys Pro Leu Val Trp Val 
        195                 200                 


<210>  1942
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  1942

Gly Arg Thr Cys Pro Lys Pro Asp Asp Leu Pro Phe Ser Thr Val Val 
1               5                   10                  15      


Pro Leu Lys Thr Phe Tyr Glu Pro Gly Glu Glu Ile Thr Tyr Ser Cys 
            20                  25                  30          


Lys Pro Gly Tyr Val Ser Arg Gly Gly Met Arg Lys Phe Ile Cys Pro 
        35                  40                  45              


Leu Thr Gly Leu Trp Pro Ile Asn Thr Leu Lys Cys Thr Pro Arg Val 
    50                  55                  60                  


Cys Pro Phe Ala Gly Ile Leu Glu Asn Gly Ala Val Arg Tyr Thr Thr 
65                  70                  75                  80  


Phe Glu Tyr Pro Asn Thr Ile Ser Phe Ser Cys Asn Thr Gly Phe Tyr 
                85                  90                  95      


Leu Asn Gly Ala Asp Ser Ala Lys Cys Thr Glu Glu Gly Lys Trp Ser 
            100                 105                 110         


Pro Glu Leu Pro Val Cys Ala Pro Ile Ile Cys Pro Pro Pro Ser Ile 
        115                 120                 125             


Pro Thr Phe Ala Thr Leu Arg Val Tyr Lys Pro Ser Ala Gly Asn Asn 
    130                 135                 140                 


Ser Leu Tyr Arg Asp Thr Ala Val Phe Glu Cys Leu Pro Gln His Ala 
145                 150                 155                 160 


Met Phe Gly Asn Asp Thr Ile Thr Cys Thr Thr His Gly Asn Trp Thr 
                165                 170                 175     


Lys Leu Pro Glu Cys Arg Glu Val Lys Cys Pro Phe Pro Ser Arg Pro 
            180                 185                 190         


Asp Asn Gly Phe Val Asn Tyr Pro Ala Lys Pro Thr Leu Tyr Tyr Lys 
        195                 200                 205             


Asp Lys Ala Thr Phe Gly Cys His Asp Gly Tyr Ser Leu Asp Gly Pro 
    210                 215                 220                 


Glu Glu Ile Glu Cys Thr Lys Leu Gly Asn Trp Ser Ala Met Pro Ser 
225                 230                 235                 240 


Cys Lys Ala Ser Cys Lys Val Pro Val Lys Lys Ala Thr Val Val Tyr 
                245                 250                 255     


Gln Gly Glu Arg Val Lys Ile Gln Glu Lys Phe Lys Asn Gly Met Leu 
            260                 265                 270         


His Gly Asp Lys Val Ser Phe Phe Cys Lys Asn Lys Glu Lys Lys Cys 
        275                 280                 285             


Ser Tyr Thr Glu Asp Ala Gln Cys Ile Asp Gly Thr Ile Glu Val Pro 
    290                 295                 300                 


Lys Cys Phe Lys Glu His Ser Ser Leu Ala Phe Trp Lys Thr Asp Ala 
305                 310                 315                 320 


Ser Asp Val Lys Pro Cys 
                325     


<210>  1943
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  1943

Glu Arg Asp Cys Arg Val Ser Ser Phe Arg Val Lys Glu Asn Phe Asp 
1               5                   10                  15      


Lys Ala Arg Phe Ser Gly Thr Trp Tyr Ala Met Ala Lys Lys Asp Pro 
            20                  25                  30          


Glu Gly Leu Phe Leu Gln Asp Asn Ile Val Ala Glu Phe Ser Val Asp 
        35                  40                  45              


Glu Thr Gly Gln Met Ser Ala Thr Ala Lys Gly Arg Val Arg Leu Leu 
    50                  55                  60                  


Asn Asn Trp Asp Val Cys Ala Asp Met Val Gly Thr Phe Thr Asp Thr 
65                  70                  75                  80  


Glu Asp Pro Ala Lys Phe Lys Met Lys Tyr Trp Gly Val Ala Ser Phe 
                85                  90                  95      


Leu Gln Lys Gly Asn Asp Asp His Trp Ile Val Asp Thr Asp Tyr Asp 
            100                 105                 110         


Thr Tyr Ala Val Gln Tyr Ser Cys Arg Leu Leu Asn Leu Asp Gly Thr 
        115                 120                 125             


Cys Ala Asp Ser Tyr Ser Phe Val Phe Ser Arg Asp Pro Asn Gly Leu 
    130                 135                 140                 


Pro Pro Glu Ala Gln Lys Ile Val Arg Gln Arg Gln Glu Glu Leu Cys 
145                 150                 155                 160 


Leu Ala Arg Gln Tyr Arg Leu Ile Val His Asn Gly Tyr Cys Asp Gly 
                165                 170                 175     


Arg Ser Glu Arg Asn Leu Leu 
            180             


<210>  1944
<211>  184
<212>  PRT
<213>  Homo Sapiens

<400>  1944

Gly Pro Val Pro Thr Pro Pro Asp Asn Ile Gln Val Gln Glu Asn Phe 
1               5                   10                  15      


Asn Ile Ser Arg Ile Tyr Gly Lys Trp Tyr Asn Leu Ala Ile Gly Ser 
            20                  25                  30          


Thr Cys Pro Trp Leu Lys Lys Ile Met Asp Arg Met Thr Val Ser Thr 
        35                  40                  45              


Leu Val Leu Gly Glu Gly Ala Thr Glu Ala Glu Ile Ser Met Thr Ser 
    50                  55                  60                  


Thr Arg Trp Arg Lys Gly Val Cys Glu Glu Thr Ser Gly Ala Tyr Glu 
65                  70                  75                  80  


Lys Thr Asp Thr Asp Gly Lys Phe Leu Tyr His Lys Ser Lys Trp Asn 
                85                  90                  95      


Ile Thr Met Glu Ser Tyr Val Val His Thr Asn Tyr Asp Glu Tyr Ala 
            100                 105                 110         


Ile Phe Leu Thr Lys Lys Phe Ser Arg His His Gly Pro Thr Ile Thr 
        115                 120                 125             


Ala Lys Leu Tyr Gly Arg Ala Pro Gln Leu Arg Glu Thr Leu Leu Gln 
    130                 135                 140                 


Asp Phe Arg Val Val Ala Gln Gly Val Gly Ile Pro Glu Asp Ser Ile 
145                 150                 155                 160 


Phe Thr Met Ala Asp Arg Gly Glu Cys Val Pro Gly Glu Gln Glu Pro 
                165                 170                 175     


Glu Pro Ile Leu Ile Pro Arg Val 
            180                 


<210>  1945
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  1945

Gln Ile Pro Leu Cys Ala Asn Leu Val Pro Val Pro Ile Thr Asn Ala 
1               5                   10                  15      


Thr Leu Asp Arg Ile Thr Gly Lys Trp Phe Tyr Ile Ala Ser Ala Phe 
            20                  25                  30          


Arg Asn Glu Glu Tyr Asn Lys Ser Val Gln Glu Ile Gln Ala Thr Phe 
        35                  40                  45              


Phe Tyr Phe Thr Pro Asn Lys Thr Glu Asp Thr Ile Phe Leu Arg Glu 
    50                  55                  60                  


Tyr Gln Thr Arg Gln Asp Gln Cys Ile Tyr Asn Thr Thr Tyr Leu Asn 
65                  70                  75                  80  


Val Gln Arg Glu Asn Gly Thr Ile Ser Arg Tyr Val Gly Gly Gln Glu 
                85                  90                  95      


His Phe Ala His Leu Leu Ile Leu Arg Asp Thr Lys Thr Tyr Met Leu 
            100                 105                 110         


Ala Phe Asp Val Asn Asp Glu Lys Asn Trp Gly Leu Ser Val Tyr Ala 
        115                 120                 125             


Asp Lys Pro Glu Thr Thr Lys Glu Gln Leu Gly Glu Phe Tyr Glu Ala 
    130                 135                 140                 


Leu Asp Cys Leu Arg Ile Pro Lys Ser Asp Val Val Tyr Thr Asp Trp 
145                 150                 155                 160 


Lys Lys Asp Lys Cys Glu Pro Leu Glu Lys Gln His Glu Lys Glu Arg 
                165                 170                 175     


Lys Gln Glu Glu Gly Glu Ser 
            180             


<210>  1946
<211>  349
<212>  PRT
<213>  Homo Sapiens

<400>  1946

Ala Pro His Gly Pro Gly Leu Ile Tyr Arg Gln Pro Asn Cys Asp Asp 
1               5                   10                  15      


Pro Glu Thr Glu Glu Ala Ala Leu Val Ala Ile Asp Tyr Ile Asn Gln 
            20                  25                  30          


Asn Leu Pro Trp Gly Tyr Lys His Thr Leu Asn Gln Ile Asp Glu Val 
        35                  40                  45              


Lys Val Trp Pro Gln Gln Pro Ser Gly Glu Leu Phe Glu Ile Glu Ile 
    50                  55                  60                  


Asp Thr Leu Glu Thr Thr Cys His Val Leu Asp Pro Thr Pro Val Ala 
65                  70                  75                  80  


Arg Cys Ser Val Arg Gln Leu Lys Glu His Ala Val Glu Gly Asp Cys 
                85                  90                  95      


Asp Phe Gln Leu Leu Lys Leu Asp Gly Lys Phe Ser Val Val Tyr Ala 
            100                 105                 110         


Lys Cys Asp Ser Ser Pro Asp Ser Ala Glu Asp Val Arg Lys Val Cys 
        115                 120                 125             


Gln Asp Cys Pro Leu Leu Ala Pro Leu Asn Asp Thr Arg Val Val His 
    130                 135                 140                 


Ala Ala Lys Ala Ala Leu Ala Ala Phe Asn Ala Gln Asn Asn Gly Ser 
145                 150                 155                 160 


Asn Phe Gln Leu Glu Glu Ile Ser Arg Ala Gln Leu Val Pro Leu Pro 
                165                 170                 175     


Pro Ser Thr Tyr Val Glu Phe Thr Val Ser Gly Thr Asp Cys Val Ala 
            180                 185                 190         


Lys Glu Ala Thr Glu Ala Ala Lys Cys Asn Leu Leu Ala Glu Lys Gln 
        195                 200                 205             


Tyr Gly Phe Cys Lys Ala Thr Leu Ser Glu Lys Leu Gly Gly Ala Glu 
    210                 215                 220                 


Val Ala Val Thr Cys Thr Val Phe Gln Thr Gln Pro Val Thr Ser Gln 
225                 230                 235                 240 


Pro Gln Pro Glu Gly Ala Asn Glu Ala Val Pro Thr Pro Val Val Asp 
                245                 250                 255     


Pro Asp Ala Pro Pro Ser Pro Pro Leu Gly Ala Pro Gly Leu Pro Pro 
            260                 265                 270         


Ala Gly Ser Pro Pro Asp Ser His Val Leu Leu Ala Ala Pro Pro Gly 
        275                 280                 285             


His Gln Leu His Arg Ala His Tyr Asp Leu Arg His Thr Phe Met Gly 
    290                 295                 300                 


Val Val Ser Leu Gly Ser Pro Ser Gly Glu Val Ser His Pro Arg Lys 
305                 310                 315                 320 


Thr Arg Thr Val Val Gln Pro Ser Val Gly Ala Ala Ala Gly Pro Val 
                325                 330                 335     


Val Pro Pro Cys Pro Gly Arg Ile Arg His Phe Lys Val 
            340                 345                 


<210>  1947
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  1947

Gly Pro Thr Gly Thr Gly Glu Ser Lys Cys Pro Leu Met Val Lys Val 
1               5                   10                  15      


Leu Asp Ala Val Arg Gly Ser Pro Ala Ile Asn Val Ala Val His Val 
            20                  25                  30          


Phe Arg Lys Ala Ala Asp Asp Thr Trp Glu Pro Phe Ala Ser Gly Lys 
        35                  40                  45              


Thr Ser Glu Ser Gly Glu Leu His Gly Leu Thr Thr Glu Glu Glu Phe 
    50                  55                  60                  


Val Glu Gly Ile Tyr Lys Val Glu Ile Asp Thr Lys Ser Tyr Trp Lys 
65                  70                  75                  80  


Ala Leu Gly Ile Ser Pro Phe His Glu His Ala Glu Val Val Phe Thr 
                85                  90                  95      


Ala Asn Asp Ser Gly Pro Arg Arg Tyr Thr Ile Ala Ala Leu Leu Ser 
            100                 105                 110         


Pro Tyr Ser Tyr Ser Thr Thr Ala Val Val Thr Asn Pro Lys Glu 
        115                 120                 125         


<210>  1948
<211>  585
<212>  PRT
<213>  Homo Sapiens

<400>  1948

Asp Ala His Lys Ser Glu Val Ala His Arg Phe Lys Asp Leu Gly Glu 
1               5                   10                  15      


Glu Asn Phe Lys Ala Leu Val Leu Ile Ala Phe Ala Gln Tyr Leu Gln 
            20                  25                  30          


Gln Cys Pro Phe Glu Asp His Val Lys Leu Val Asn Glu Val Thr Glu 
        35                  40                  45              


Phe Ala Lys Thr Cys Val Ala Asp Glu Ser Ala Glu Asn Cys Asp Lys 
    50                  55                  60                  


Ser Leu His Thr Leu Phe Gly Asp Lys Leu Cys Thr Val Ala Thr Leu 
65                  70                  75                  80  


Arg Glu Thr Tyr Gly Glu Met Ala Asp Cys Cys Ala Lys Gln Glu Pro 
                85                  90                  95      


Glu Arg Asn Glu Cys Phe Leu Gln His Lys Asp Asp Asn Pro Asn Leu 
            100                 105                 110         


Pro Arg Leu Val Arg Pro Glu Val Asp Val Met Cys Thr Ala Phe His 
        115                 120                 125             


Asp Asn Glu Glu Thr Phe Leu Lys Lys Tyr Leu Tyr Glu Ile Ala Arg 
    130                 135                 140                 


Arg His Pro Tyr Phe Tyr Ala Pro Glu Leu Leu Phe Phe Ala Lys Arg 
145                 150                 155                 160 


Tyr Lys Ala Ala Phe Thr Glu Cys Cys Gln Ala Ala Asp Lys Ala Ala 
                165                 170                 175     


Cys Leu Leu Pro Lys Leu Asp Glu Leu Arg Asp Glu Gly Lys Ala Ser 
            180                 185                 190         


Ser Ala Lys Gln Arg Leu Lys Cys Ala Ser Leu Gln Lys Phe Gly Glu 
        195                 200                 205             


Arg Ala Phe Lys Ala Trp Ala Val Ala Arg Leu Ser Gln Arg Phe Pro 
    210                 215                 220                 


Lys Ala Glu Phe Ala Glu Val Ser Lys Leu Val Thr Asp Leu Thr Lys 
225                 230                 235                 240 


Val His Thr Glu Cys Cys His Gly Asp Leu Leu Glu Cys Ala Asp Asp 
                245                 250                 255     


Arg Ala Asp Leu Ala Lys Tyr Ile Cys Glu Asn Gln Asp Ser Ile Ser 
            260                 265                 270         


Ser Lys Leu Lys Glu Cys Cys Glu Lys Pro Leu Leu Glu Lys Ser His 
        275                 280                 285             


Cys Ile Ala Glu Val Glu Asn Asp Glu Met Pro Ala Asp Leu Pro Ser 
    290                 295                 300                 


Leu Ala Ala Asp Phe Val Glu Ser Lys Asp Val Cys Lys Asn Tyr Ala 
305                 310                 315                 320 


Glu Ala Lys Asp Val Phe Leu Gly Met Phe Leu Tyr Glu Tyr Ala Arg 
                325                 330                 335     


Arg His Pro Asp Tyr Ser Val Val Leu Leu Leu Arg Leu Ala Lys Thr 
            340                 345                 350         


Tyr Glu Thr Thr Leu Glu Lys Cys Cys Ala Ala Ala Asp Pro His Glu 
        355                 360                 365             


Cys Tyr Ala Lys Val Phe Asp Glu Phe Lys Pro Leu Val Glu Glu Pro 
    370                 375                 380                 


Gln Asn Leu Ile Lys Gln Asn Cys Glu Leu Phe Glu Gln Leu Gly Glu 
385                 390                 395                 400 


Tyr Lys Phe Gln Asn Ala Leu Leu Val Arg Tyr Thr Lys Lys Val Pro 
                405                 410                 415     


Gln Val Ser Thr Pro Thr Leu Val Glu Val Ser Arg Asn Leu Gly Lys 
            420                 425                 430         


Val Gly Ser Lys Cys Cys Lys His Pro Glu Ala Lys Arg Met Pro Cys 
        435                 440                 445             


Ala Glu Asp Tyr Leu Ser Val Val Leu Asn Gln Leu Cys Val Leu His 
    450                 455                 460                 


Glu Lys Thr Pro Val Ser Asp Arg Val Thr Lys Cys Cys Thr Glu Ser 
465                 470                 475                 480 


Leu Val Asn Arg Arg Pro Cys Phe Ser Ala Leu Glu Val Asp Glu Thr 
                485                 490                 495     


Tyr Val Pro Lys Glu Phe Asn Ala Glu Thr Phe Thr Phe His Ala Asp 
            500                 505                 510         


Ile Cys Thr Leu Ser Glu Lys Glu Arg Gln Ile Lys Lys Gln Thr Ala 
        515                 520                 525             


Leu Val Glu Leu Val Lys His Lys Pro Lys Ala Thr Lys Glu Gln Leu 
    530                 535                 540                 


Lys Ala Val Met Asp Asp Phe Ala Ala Phe Val Glu Lys Cys Cys Lys 
545                 550                 555                 560 


Ala Asp Asp Lys Glu Thr Cys Phe Ala Glu Glu Gly Lys Lys Leu Val 
                565                 570                 575     


Ala Ala Ser Gln Ala Ala Leu Gly Leu 
            580                 585 


<210>  1949
<211>  591
<212>  PRT
<213>  Homo Sapiens

<400>  1949

Arg Thr Leu His Arg Asn Glu Tyr Gly Ile Ala Ser Ile Leu Asp Ser 
1               5                   10                  15      


Tyr Gln Cys Thr Ala Glu Ile Ser Leu Ala Asp Leu Ala Thr Ile Phe 
            20                  25                  30          


Phe Ala Gln Phe Val Gln Glu Ala Thr Tyr Lys Glu Val Ser Lys Met 
        35                  40                  45              


Val Lys Asp Ala Leu Thr Ala Ile Glu Lys Pro Thr Gly Asp Glu Gln 
    50                  55                  60                  


Ser Ser Gly Cys Leu Glu Asn Gln Leu Pro Ala Phe Leu Glu Glu Leu 
65                  70                  75                  80  


Cys His Glu Lys Glu Ile Leu Glu Lys Tyr Gly His Ser Asp Cys Cys 
                85                  90                  95      


Ser Gln Ser Glu Glu Gly Arg His Asn Cys Phe Leu Ala His Lys Lys 
            100                 105                 110         


Pro Thr Pro Ala Ser Ile Pro Leu Phe Gln Val Pro Glu Pro Val Thr 
        115                 120                 125             


Ser Cys Glu Ala Tyr Glu Glu Asp Arg Glu Thr Phe Met Asn Lys Phe 
    130                 135                 140                 


Ile Tyr Glu Ile Ala Arg Arg His Pro Phe Leu Tyr Ala Pro Thr Ile 
145                 150                 155                 160 


Leu Leu Trp Ala Ala Arg Tyr Asp Lys Ile Ile Pro Ser Cys Cys Lys 
                165                 170                 175     


Ala Glu Asn Ala Val Glu Cys Phe Gln Thr Lys Ala Ala Thr Val Thr 
            180                 185                 190         


Lys Glu Leu Arg Glu Ser Ser Leu Leu Asn Gln His Ala Cys Ala Val 
        195                 200                 205             


Met Lys Asn Phe Gly Thr Arg Thr Phe Gln Ala Ile Thr Val Thr Lys 
    210                 215                 220                 


Leu Ser Gln Lys Phe Thr Lys Val Asn Phe Thr Glu Ile Gln Lys Leu 
225                 230                 235                 240 


Val Leu Asp Val Ala His Val His Glu His Cys Cys Arg Gly Asp Val 
                245                 250                 255     


Leu Asp Cys Leu Gln Asp Gly Glu Lys Ile Met Ser Tyr Ile Cys Ser 
            260                 265                 270         


Gln Gln Asp Thr Leu Ser Asn Lys Ile Thr Glu Cys Cys Lys Leu Thr 
        275                 280                 285             


Thr Leu Glu Arg Gly Gln Cys Ile Ile His Ala Glu Asn Asp Glu Lys 
    290                 295                 300                 


Pro Glu Gly Leu Ser Pro Asn Leu Asn Arg Phe Leu Gly Asp Arg Asp 
305                 310                 315                 320 


Phe Asn Gln Phe Ser Ser Gly Glu Lys Asn Ile Phe Leu Ala Ser Phe 
                325                 330                 335     


Val His Glu Tyr Ser Arg Arg His Pro Gln Leu Ala Val Ser Val Ile 
            340                 345                 350         


Leu Arg Val Ala Lys Gly Tyr Gln Glu Leu Leu Glu Lys Cys Phe Gln 
        355                 360                 365             


Thr Glu Asn Pro Leu Glu Cys Gln Asp Lys Gly Glu Glu Glu Leu Gln 
    370                 375                 380                 


Lys Tyr Ile Gln Glu Ser Gln Ala Leu Ala Lys Arg Ser Cys Gly Leu 
385                 390                 395                 400 


Phe Gln Lys Leu Gly Glu Tyr Tyr Leu Gln Asn Ala Phe Leu Val Ala 
                405                 410                 415     


Tyr Thr Lys Lys Ala Pro Gln Leu Thr Ser Ser Glu Leu Met Ala Ile 
            420                 425                 430         


Thr Arg Lys Met Ala Ala Thr Ala Ala Thr Cys Cys Gln Leu Ser Glu 
        435                 440                 445             


Asp Lys Leu Leu Ala Cys Gly Glu Gly Ala Ala Asp Ile Ile Ile Gly 
    450                 455                 460                 


His Leu Cys Ile Arg His Glu Met Thr Pro Val Asn Pro Gly Val Gly 
465                 470                 475                 480 


Gln Cys Cys Thr Ser Ser Tyr Ala Asn Arg Arg Pro Cys Phe Ser Ser 
                485                 490                 495     


Leu Val Val Asp Glu Thr Tyr Val Pro Pro Ala Phe Ser Asp Asp Lys 
            500                 505                 510         


Phe Ile Phe His Lys Asp Leu Cys Gln Ala Gln Gly Val Ala Leu Gln 
        515                 520                 525             


Thr Met Lys Gln Glu Phe Leu Ile Asn Leu Val Lys Gln Lys Pro Gln 
    530                 535                 540                 


Ile Thr Glu Glu Gln Leu Glu Ala Val Ile Ala Asp Phe Ser Gly Leu 
545                 550                 555                 560 


Leu Glu Lys Cys Cys Gln Gly Gln Glu Gln Glu Val Cys Phe Ala Glu 
                565                 570                 575     


Glu Gly Gln Lys Leu Ile Ser Lys Thr Arg Ala Ala Leu Gly Val 
            580                 585                 590     


<210>  1950
<211>  458
<212>  PRT
<213>  Homo Sapiens

<400>  1950

Leu Glu Arg Gly Arg Asp Tyr Glu Lys Asn Lys Val Cys Lys Glu Phe 
1               5                   10                  15      


Ser His Leu Gly Lys Glu Asp Phe Thr Ser Leu Ser Leu Val Leu Tyr 
            20                  25                  30          


Ser Arg Lys Phe Pro Ser Gly Thr Phe Glu Gln Val Ser Gln Leu Val 
        35                  40                  45              


Lys Glu Val Val Ser Leu Thr Glu Ala Cys Cys Ala Glu Gly Ala Asp 
    50                  55                  60                  


Pro Asp Cys Tyr Asp Thr Arg Thr Ser Ala Leu Ser Ala Lys Ser Cys 
65                  70                  75                  80  


Glu Ser Asn Ser Pro Phe Pro Val His Pro Gly Thr Ala Glu Cys Cys 
                85                  90                  95      


Thr Lys Glu Gly Leu Glu Arg Lys Leu Cys Met Ala Ala Leu Lys His 
            100                 105                 110         


Gln Pro Gln Glu Phe Pro Thr Tyr Val Glu Pro Thr Asn Asp Glu Ile 
        115                 120                 125             


Cys Glu Ala Phe Arg Lys Asp Pro Lys Glu Tyr Ala Asn Gln Phe Met 
    130                 135                 140                 


Trp Glu Tyr Ser Thr Asn Tyr Gly Gln Ala Pro Leu Ser Leu Leu Val 
145                 150                 155                 160 


Ser Tyr Thr Lys Ser Tyr Leu Ser Met Val Gly Ser Cys Cys Thr Ser 
                165                 170                 175     


Ala Ser Pro Thr Val Cys Phe Leu Lys Glu Arg Leu Gln Leu Lys His 
            180                 185                 190         


Leu Ser Leu Leu Thr Thr Leu Ser Asn Arg Val Cys Ser Gln Tyr Ala 
        195                 200                 205             


Ala Tyr Gly Glu Lys Lys Ser Arg Leu Ser Asn Leu Ile Lys Leu Ala 
    210                 215                 220                 


Gln Lys Val Pro Thr Ala Asp Leu Glu Asp Val Leu Pro Leu Ala Glu 
225                 230                 235                 240 


Asp Ile Thr Asn Ile Leu Ser Lys Cys Cys Glu Ser Ala Ser Glu Asp 
                245                 250                 255     


Cys Met Ala Lys Glu Leu Pro Glu His Thr Val Lys Leu Cys Asp Asn 
            260                 265                 270         


Leu Ser Thr Lys Asn Ser Lys Phe Glu Asp Cys Cys Gln Glu Lys Thr 
        275                 280                 285             


Ala Met Asp Val Phe Val Cys Thr Tyr Phe Met Pro Ala Ala Gln Leu 
    290                 295                 300                 


Pro Glu Leu Pro Asp Val Glu Leu Pro Thr Asn Lys Asp Val Cys Asp 
305                 310                 315                 320 


Pro Gly Asn Thr Lys Val Met Asp Lys Tyr Thr Phe Glu Leu Ser Arg 
                325                 330                 335     


Arg Thr His Leu Pro Glu Val Phe Leu Ser Lys Val Leu Glu Pro Thr 
            340                 345                 350         


Leu Lys Ser Leu Gly Glu Cys Cys Asp Val Glu Asp Ser Thr Thr Cys 
        355                 360                 365             


Phe Asn Ala Lys Gly Pro Leu Leu Lys Lys Glu Leu Ser Ser Phe Ile 
    370                 375                 380                 


Asp Lys Gly Gln Glu Leu Cys Ala Asp Tyr Ser Glu Asn Thr Phe Thr 
385                 390                 395                 400 


Glu Tyr Lys Lys Lys Leu Ala Glu Arg Leu Lys Ala Lys Leu Pro Asp 
                405                 410                 415     


Ala Thr Pro Thr Glu Leu Ala Lys Leu Val Asn Lys Arg Ser Asp Phe 
            420                 425                 430         


Ala Ser Asn Cys Cys Ser Ile Asn Ser Pro Pro Leu Tyr Cys Asp Ser 
        435                 440                 445             


Glu Ile Asp Ala Glu Leu Lys Asn Ile Leu 
    450                 455             


<210>  1951
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  1951

Gln Asp Leu Asp Glu Asp Val Ser Gln Glu Asp Val Pro Leu Val Ile 
1               5                   10                  15      


Ser Asp Gly Gly Asp Ser Glu Gln Phe Ile Asp Glu Glu Arg Gln Gly 
            20                  25                  30          


Pro Pro Leu Gly Gly Gln Gln Ser Gln Pro Ser Ala Gly Asp Gly Asn 
        35                  40                  45              


Gln Asp Asp Gly Pro Gln Gln Gly Pro Pro Gln Gln Gly Gly Gln Gln 
    50                  55                  60                  


Gln Gln Gly Pro Pro Pro Pro Gln Gly Lys Pro Gln Gly Pro Pro Gln 
65                  70                  75                  80  


Gln Gly Gly His Pro Pro Pro Pro Gln Gly Arg Pro Gln Gly Pro Pro 
                85                  90                  95      


Gln Gln Gly Gly His Pro Arg Pro Pro Arg Gly Arg Pro Gln Gly Pro 
            100                 105                 110         


Pro Gln Gln Gly Gly His Gln Gln Gly Pro Pro Pro Pro Pro Pro Gly 
        115                 120                 125             


Lys Pro Gln Gly Pro Pro Pro Gln Gly Gly Arg Pro Gln Gly Pro Pro 
    130                 135                 140                 


Gln Gly Gln Ser Pro Gln 
145                 150 


<210>  1952
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  1952

Gln Arg Gly Pro Arg Gly Pro Tyr Pro Pro Gly Pro Leu Ala Pro Pro 
1               5                   10                  15      


Gln Pro Phe Gly Pro Gly Phe Val Pro Pro Pro Pro Pro Pro Pro Tyr 
            20                  25                  30          


Gly Pro Gly Arg Ile Pro Pro Pro Pro Pro Ala Pro Tyr Gly Pro Gly 
        35                  40                  45              


Ile Phe Pro Pro Pro Pro Pro Gln Pro 
    50                  55          


<210>  1953
<211>  49
<212>  PRT
<213>  Homo Sapiens

<400>  1953

Tyr Leu Tyr Gln Trp Leu Gly Ala Pro Val Pro Tyr Pro Asp Pro Leu 
1               5                   10                  15      


Glu Pro Arg Arg Glu Val Cys Glu Leu Asn Pro Asp Cys Asp Glu Leu 
            20                  25                  30          


Ala Asp His Ile Gly Phe Gln Glu Ala Tyr Arg Arg Phe Tyr Gly Pro 
        35                  40                  45              


Val 
    


<210>  1954
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  1954

Gln Asp Asn Ser Arg Tyr Thr His Phe Leu Thr Gln His Tyr Asp Ala 
1               5                   10                  15      


Lys Pro Gln Gly Arg Asp Asp Arg Tyr Cys Glu Ser Ile Met Arg Arg 
            20                  25                  30          


Arg Gly Leu Thr Ser Pro Cys Lys Asp Ile Asn Thr Phe Ile His Gly 
        35                  40                  45              


Asn Lys Arg Ser Ile Lys Ala Ile Cys Glu Asn Lys Asn Gly Asn Pro 
    50                  55                  60                  


His Arg Glu Asn Leu Arg Ile Ser Lys Ser Ser Phe Gln Val Thr Thr 
65                  70                  75                  80  


Cys Lys Leu His Gly Gly Ser Pro Trp Pro Pro Cys Gln Tyr Arg Ala 
                85                  90                  95      


Thr Ala Gly Phe Arg Asn Val Val Val Ala Cys Glu Asn Gly Leu Pro 
            100                 105                 110         


Val His Leu Asp Gln Ser Ile Phe Arg Arg Pro 
        115                 120             


<210>  1955
<211>  607
<212>  PRT
<213>  Homo Sapiens

<400>  1955

Glu Cys Val Thr Gln Leu Leu Lys Asp Thr Cys Phe Glu Gly Gly Asp 
1               5                   10                  15      


Ile Thr Thr Val Phe Thr Pro Ser Ala Lys Tyr Cys Gln Val Val Cys 
            20                  25                  30          


Thr Tyr His Pro Arg Cys Leu Leu Phe Thr Phe Thr Ala Glu Ser Pro 
        35                  40                  45              


Ser Glu Asp Pro Thr Arg Trp Phe Thr Cys Val Leu Lys Asp Ser Val 
    50                  55                  60                  


Thr Glu Thr Leu Pro Arg Val Asn Arg Thr Ala Ala Ile Ser Gly Tyr 
65                  70                  75                  80  


Ser Phe Lys Gln Cys Ser His Gln Ile Ser Ala Cys Asn Lys Asp Ile 
                85                  90                  95      


Tyr Val Asp Leu Asp Met Lys Gly Ile Asn Tyr Asn Ser Ser Val Ala 
            100                 105                 110         


Lys Ser Ala Gln Glu Cys Gln Glu Arg Cys Thr Asp Asp Val His Cys 
        115                 120                 125             


His Phe Phe Thr Tyr Ala Thr Arg Gln Phe Pro Ser Leu Glu His Arg 
    130                 135                 140                 


Asn Ile Cys Leu Leu Lys His Thr Gln Thr Gly Thr Pro Thr Arg Ile 
145                 150                 155                 160 


Thr Lys Leu Asp Lys Val Val Ser Gly Phe Ser Leu Lys Ser Cys Ala 
                165                 170                 175     


Leu Ser Asn Leu Ala Cys Ile Arg Asp Ile Phe Pro Asn Thr Val Phe 
            180                 185                 190         


Ala Asp Ser Asn Ile Asp Ser Val Met Ala Pro Asp Ala Phe Val Cys 
        195                 200                 205             


Gly Arg Ile Cys Thr His His Pro Gly Cys Leu Phe Phe Thr Phe Phe 
    210                 215                 220                 


Ser Gln Glu Trp Pro Lys Glu Ser Gln Arg Asn Leu Cys Leu Leu Lys 
225                 230                 235                 240 


Thr Ser Glu Ser Gly Leu Pro Ser Thr Arg Ile Lys Lys Ser Lys Ala 
                245                 250                 255     


Leu Ser Gly Phe Ser Leu Gln Ser Cys Arg His Ser Ile Pro Val Phe 
            260                 265                 270         


Cys His Ser Ser Phe Tyr His Asp Thr Asp Phe Leu Gly Glu Glu Leu 
        275                 280                 285             


Asp Ile Val Ala Ala Lys Ser His Glu Ala Cys Gln Lys Leu Cys Thr 
    290                 295                 300                 


Asn Ala Val Arg Cys Gln Phe Phe Thr Tyr Thr Pro Ala Gln Ala Ser 
305                 310                 315                 320 


Cys Asn Glu Gly Lys Gly Lys Cys Tyr Leu Lys Leu Ser Ser Asn Gly 
                325                 330                 335     


Ser Pro Thr Lys Ile Leu His Gly Arg Gly Gly Ile Ser Gly Tyr Thr 
            340                 345                 350         


Leu Arg Leu Cys Lys Met Asp Asn Glu Cys Thr Thr Lys Ile Lys Pro 
        355                 360                 365             


Arg Ile Val Gly Gly Thr Ala Ser Val Arg Gly Glu Trp Pro Trp Gln 
    370                 375                 380                 


Val Thr Leu His Thr Thr Ser Pro Thr Gln Arg His Leu Cys Gly Gly 
385                 390                 395                 400 


Ser Ile Ile Gly Asn Gln Trp Ile Leu Thr Ala Ala His Cys Phe Tyr 
                405                 410                 415     


Gly Val Glu Ser Pro Lys Ile Leu Arg Val Tyr Ser Gly Ile Leu Asn 
            420                 425                 430         


Gln Ser Glu Ile Lys Glu Asp Thr Ser Phe Phe Gly Val Gln Glu Ile 
        435                 440                 445             


Ile Ile His Asp Gln Tyr Lys Met Ala Glu Ser Gly Tyr Asp Ile Ala 
    450                 455                 460                 


Leu Leu Lys Leu Glu Thr Thr Val Asn Tyr Thr Asp Ser Gln Arg Pro 
465                 470                 475                 480 


Ile Cys Leu Pro Ser Lys Gly Asp Arg Asn Val Ile Tyr Thr Asp Cys 
                485                 490                 495     


Trp Val Thr Gly Trp Gly Tyr Arg Lys Leu Arg Asp Lys Ile Gln Asn 
            500                 505                 510         


Thr Leu Gln Lys Ala Lys Ile Pro Leu Val Thr Asn Glu Glu Cys Gln 
        515                 520                 525             


Lys Arg Tyr Arg Gly His Lys Ile Thr His Lys Met Ile Cys Ala Gly 
    530                 535                 540                 


Tyr Arg Glu Gly Gly Lys Asp Ala Cys Lys Gly Asp Ser Gly Gly Pro 
545                 550                 555                 560 


Leu Ser Cys Lys His Asn Glu Val Trp His Leu Val Gly Ile Thr Ser 
                565                 570                 575     


Trp Gly Glu Gly Cys Ala Gln Arg Glu Arg Pro Gly Val Tyr Thr Asn 
            580                 585                 590         


Val Val Glu Tyr Val Asp Trp Ile Leu Glu Lys Thr Gln Ala Val 
        595                 600                 605         


<210>  1956
<211>  619
<212>  PRT
<213>  Homo Sapiens

<400>  1956

Gly Cys Leu Thr Gln Leu Tyr Glu Asn Ala Phe Phe Arg Gly Gly Asp 
1               5                   10                  15      


Val Ala Ser Met Tyr Thr Pro Asn Ala Gln Tyr Cys Gln Met Arg Cys 
            20                  25                  30          


Thr Phe His Pro Arg Cys Leu Leu Phe Ser Phe Leu Pro Ala Ser Ser 
        35                  40                  45              


Ile Asn Asp Met Glu Lys Arg Phe Gly Cys Phe Leu Lys Asp Ser Val 
    50                  55                  60                  


Thr Gly Thr Leu Pro Lys Val His Arg Thr Gly Ala Val Ser Gly His 
65                  70                  75                  80  


Ser Leu Lys Gln Cys Gly His Gln Ile Ser Ala Cys His Arg Asp Ile 
                85                  90                  95      


Tyr Lys Gly Val Asp Met Arg Gly Val Asn Phe Asn Val Ser Lys Val 
            100                 105                 110         


Ser Ser Val Glu Glu Cys Gln Lys Arg Cys Thr Asn Asn Ile Arg Cys 
        115                 120                 125             


Gln Phe Phe Ser Tyr Ala Thr Gln Thr Phe His Lys Ala Glu Tyr Arg 
    130                 135                 140                 


Asn Asn Cys Leu Leu Lys Tyr Ser Pro Gly Gly Thr Pro Thr Ala Ile 
145                 150                 155                 160 


Lys Val Leu Ser Asn Val Glu Ser Gly Phe Ser Leu Lys Pro Cys Ala 
                165                 170                 175     


Leu Ser Glu Ile Gly Cys His Met Asn Ile Phe Gln His Leu Ala Phe 
            180                 185                 190         


Ser Asp Val Asp Val Ala Arg Val Leu Thr Pro Asp Ala Phe Val Cys 
        195                 200                 205             


Arg Thr Ile Cys Thr Tyr His Pro Asn Cys Leu Phe Phe Thr Phe Tyr 
    210                 215                 220                 


Thr Asn Val Trp Lys Ile Glu Ser Gln Arg Asn Val Cys Leu Leu Lys 
225                 230                 235                 240 


Thr Ser Glu Ser Gly Thr Pro Ser Ser Ser Thr Pro Gln Glu Asn Thr 
                245                 250                 255     


Ile Ser Gly Tyr Ser Leu Leu Thr Cys Lys Arg Thr Leu Pro Glu Pro 
            260                 265                 270         


Cys His Ser Lys Ile Tyr Pro Gly Val Asp Phe Gly Gly Glu Glu Leu 
        275                 280                 285             


Asn Val Thr Phe Val Lys Gly Val Asn Val Cys Gln Glu Thr Cys Thr 
    290                 295                 300                 


Lys Met Ile Arg Cys Gln Phe Phe Thr Tyr Ser Leu Leu Pro Glu Asp 
305                 310                 315                 320 


Cys Lys Glu Glu Lys Cys Lys Cys Phe Leu Arg Leu Ser Met Asp Gly 
                325                 330                 335     


Ser Pro Thr Arg Ile Ala Tyr Gly Thr Gln Gly Ser Ser Gly Tyr Ser 
            340                 345                 350         


Leu Arg Leu Cys Asn Thr Gly Asp Asn Ser Val Cys Thr Thr Lys Thr 
        355                 360                 365             


Ser Thr Arg Ile Val Gly Gly Thr Asn Ser Ser Trp Gly Glu Trp Pro 
    370                 375                 380                 


Trp Gln Val Ser Leu Gln Val Lys Leu Thr Ala Gln Arg His Leu Cys 
385                 390                 395                 400 


Gly Gly Ser Leu Ile Gly His Gln Trp Val Leu Thr Ala Ala His Cys 
                405                 410                 415     


Phe Asp Gly Leu Pro Leu Gln Asp Val Trp Arg Ile Tyr Ser Gly Ile 
            420                 425                 430         


Leu Asn Leu Ser Asp Ile Thr Lys Asp Thr Pro Phe Ser Gln Ile Lys 
        435                 440                 445             


Glu Ile Ile Ile His Gln Asn Tyr Lys Val Ser Glu Gly Asn His Asp 
    450                 455                 460                 


Ile Ala Leu Ile Lys Leu Gln Ala Pro Leu Asn Tyr Thr Glu Phe Gln 
465                 470                 475                 480 


Lys Pro Ile Cys Leu Pro Ser Lys Gly Asp Thr Ser Thr Ile Tyr Thr 
                485                 490                 495     


Asn Cys Trp Val Thr Gly Trp Gly Phe Ser Lys Glu Lys Gly Glu Ile 
            500                 505                 510         


Gln Asn Ile Leu Gln Lys Val Asn Ile Pro Leu Val Thr Asn Glu Glu 
        515                 520                 525             


Cys Gln Lys Arg Tyr Gln Asp Tyr Lys Ile Thr Gln Arg Met Val Cys 
    530                 535                 540                 


Ala Gly Tyr Lys Glu Gly Gly Lys Asp Ala Cys Lys Gly Asp Ser Gly 
545                 550                 555                 560 


Gly Pro Leu Val Cys Lys His Asn Gly Met Trp Arg Leu Val Gly Ile 
                565                 570                 575     


Thr Ser Trp Gly Glu Gly Cys Ala Arg Arg Glu Gln Pro Gly Val Tyr 
            580                 585                 590         


Thr Lys Val Ala Glu Tyr Met Asp Trp Ile Leu Glu Lys Thr Gln Ser 
        595                 600                 605             


Ser Asp Gly Lys Ala Gln Met Gln Ser Pro Ala 
    610                 615                 


<210>  1957
<211>  170
<212>  PRT
<213>  Homo Sapiens

<400>  1957

Phe Val Leu Thr Glu Gly Asn Pro Arg Trp Glu Gln Thr His Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Glu Asn Tyr Thr Pro Asp Leu Pro Arg Ala Asp Val Asp 
            20                  25                  30          


His Ala Ile Glu Lys Ala Phe Gln Leu Trp Ser Asn Val Thr Pro Leu 
        35                  40                  45              


Thr Phe Thr Lys Val Ser Glu Gly Gln Ala Asp Ile Met Ile Ser Phe 
    50                  55                  60                  


Val Arg Gly Asp His Arg Asp Asn Ser Pro Phe Asp Gly Pro Gly Gly 
65                  70                  75                  80  


Asn Leu Ala His Ala Phe Gln Pro Gly Pro Gly Ile Gly Gly Asp Ala 
                85                  90                  95      


His Phe Asp Glu Asp Glu Arg Trp Thr Asn Asn Phe Arg Glu Tyr Asn 
            100                 105                 110         


Leu His Arg Val Ala Ala His Glu Leu Gly His Ser Leu Gly Leu Ser 
        115                 120                 125             


His Ser Thr Asp Ile Gly Ala Leu Met Tyr Pro Ser Tyr Thr Phe Ser 
    130                 135                 140                 


Gly Asp Val Gln Leu Ala Gln Asp Asp Ile Asp Gly Ile Gln Ala Ile 
145                 150                 155                 160 


Tyr Gly Arg Ser Gln Asn Pro Val Gln Pro 
                165                 170 


<210>  1958
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  1958

Ser Gly Lys Ser Phe Lys Ala Gly Val Cys Pro Pro Lys Lys Ser Ala 
1               5                   10                  15      


Gln Cys Leu Arg Tyr Lys Lys Pro Glu Cys Gln Ser Asp Trp Gln Cys 
            20                  25                  30          


Pro Gly Lys Lys Arg Cys Cys Pro Asp Thr Cys Gly Ile Lys Cys Leu 
        35                  40                  45              


Asp Pro Val Asp Thr Pro Asn Pro Thr Arg Arg Lys Pro Gly Lys Cys 
    50                  55                  60                  


Pro Val Thr Tyr Gly Gln Cys Leu Met Leu Asn Pro Pro Asn Phe Cys 
65                  70                  75                  80  


Glu Met Asp Gly Gln Cys Lys Arg Asp Leu Lys Cys Cys Met Gly Met 
                85                  90                  95      


Cys Gly Lys Ser Cys Val Ser Pro Val Lys Ala 
            100                 105         


<210>  1959
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  1959

Met Ala Gln Gln Trp Ser Leu Gln Arg Leu Ala Gly Arg His Pro Gln 
1               5                   10                  15      


Asp Ser Tyr Glu Asp Ser Thr Gln Ser Ser Ile Phe Thr Tyr Thr Asn 
            20                  25                  30          


Ser Asn Ser Thr Arg Gly Pro Phe Glu Gly Pro Asn Tyr His Ile Ala 
        35                  40                  45              


Pro Arg Trp Val 
    50          


<210>  1960
<211>  549
<212>  PRT
<213>  Homo Sapiens

<400>  1960

Asn Cys Gly Pro Pro Pro Thr Leu Ser Phe Ala Ala Pro Met Asp Ile 
1               5                   10                  15      


Thr Leu Thr Glu Thr Arg Phe Lys Thr Gly Thr Thr Leu Lys Tyr Thr 
            20                  25                  30          


Cys Leu Pro Gly Tyr Val Arg Ser His Ser Thr Gln Thr Leu Thr Cys 
        35                  40                  45              


Asn Ser Asp Gly Glu Trp Val Tyr Asn Thr Phe Cys Ile Tyr Lys Arg 
    50                  55                  60                  


Cys Arg His Pro Gly Glu Leu Arg Asn Gly Gln Val Glu Ile Lys Thr 
65                  70                  75                  80  


Asp Leu Ser Phe Gly Ser Gln Ile Glu Phe Ser Cys Ser Glu Gly Phe 
                85                  90                  95      


Phe Leu Ile Gly Ser Thr Thr Ser Arg Cys Glu Val Gln Asp Arg Gly 
            100                 105                 110         


Val Gly Trp Ser His Pro Leu Pro Gln Cys Glu Ile Val Lys Cys Lys 
        115                 120                 125             


Pro Pro Pro Asp Ile Arg Asn Gly Arg His Ser Gly Glu Glu Asn Phe 
    130                 135                 140                 


Tyr Ala Tyr Gly Phe Ser Val Thr Tyr Ser Cys Asp Pro Arg Phe Ser 
145                 150                 155                 160 


Leu Leu Gly His Ala Ser Ile Ser Cys Thr Val Glu Asn Glu Thr Ile 
                165                 170                 175     


Gly Val Trp Arg Pro Ser Pro Pro Thr Cys Glu Lys Ile Thr Cys Arg 
            180                 185                 190         


Lys Pro Asp Val Ser His Gly Glu Met Val Ser Gly Phe Gly Pro Ile 
        195                 200                 205             


Tyr Asn Tyr Lys Asp Thr Ile Val Phe Lys Cys Gln Lys Gly Phe Val 
    210                 215                 220                 


Leu Arg Gly Ser Ser Val Ile His Cys Asp Ala Asp Ser Lys Trp Asn 
225                 230                 235                 240 


Pro Ser Pro Pro Ala Cys Glu Pro Asn Ser Cys Ile Asn Leu Pro Asp 
                245                 250                 255     


Ile Pro His Ala Ser Trp Glu Thr Tyr Pro Arg Pro Thr Lys Glu Asp 
            260                 265                 270         


Val Tyr Val Val Gly Thr Val Leu Arg Tyr Arg Cys His Pro Gly Tyr 
        275                 280                 285             


Lys Pro Thr Thr Asp Glu Pro Thr Thr Val Ile Cys Gln Lys Asn Leu 
    290                 295                 300                 


Arg Trp Thr Pro Tyr Gln Gly Cys Glu Ala Leu Cys Cys Pro Glu Pro 
305                 310                 315                 320 


Lys Leu Asn Asn Gly Glu Ile Thr Gln His Arg Lys Ser Arg Pro Ala 
                325                 330                 335     


Asn His Cys Val Tyr Phe Tyr Gly Asp Glu Ile Ser Phe Ser Cys His 
            340                 345                 350         


Glu Thr Ser Arg Phe Ser Ala Ile Cys Gln Gly Asp Gly Thr Trp Ser 
        355                 360                 365             


Pro Arg Thr Pro Ser Cys Gly Asp Ile Cys Asn Phe Pro Pro Lys Ile 
    370                 375                 380                 


Ala His Gly His Tyr Lys Gln Ser Ser Ser Tyr Ser Phe Phe Lys Glu 
385                 390                 395                 400 


Glu Ile Ile Tyr Glu Cys Asp Lys Gly Tyr Ile Leu Val Gly Gln Ala 
                405                 410                 415     


Lys Leu Ser Cys Ser Tyr Ser His Trp Ser Ala Pro Ala Pro Gln Cys 
            420                 425                 430         


Lys Ala Leu Cys Arg Lys Pro Glu Leu Val Asn Gly Arg Leu Ser Val 
        435                 440                 445             


Asp Lys Asp Gln Tyr Val Glu Pro Glu Asn Val Thr Ile Gln Cys Asp 
    450                 455                 460                 


Ser Gly Tyr Gly Val Val Gly Pro Gln Ser Ile Thr Cys Ser Gly Asn 
465                 470                 475                 480 


Arg Thr Trp Tyr Pro Glu Val Pro Lys Cys Glu Trp Glu Thr Pro Glu 
                485                 490                 495     


Gly Cys Glu Gln Val Leu Thr Gly Lys Arg Leu Met Gln Cys Leu Pro 
            500                 505                 510         


Asn Pro Glu Asp Val Lys Met Ala Leu Glu Val Tyr Lys Leu Ser Leu 
        515                 520                 525             


Glu Ile Glu Gln Leu Glu Leu Gln Arg Asp Ser Ala Arg Gln Ser Thr 
    530                 535                 540                 


Leu Asp Lys Glu Leu 
545                 


<210>  1961
<211>  459
<212>  PRT
<213>  Homo Sapiens

<400>  1961

Asp Gln Glu Ser Cys Lys Gly Arg Cys Thr Glu Gly Phe Asn Val Asp 
1               5                   10                  15      


Lys Lys Cys Gln Cys Asp Glu Leu Cys Ser Tyr Tyr Gln Ser Cys Cys 
            20                  25                  30          


Thr Asp Tyr Thr Ala Glu Cys Lys Pro Gln Val Thr Arg Gly Asp Val 
        35                  40                  45              


Phe Thr Met Pro Glu Asp Glu Tyr Thr Val Tyr Asp Asp Gly Glu Glu 
    50                  55                  60                  


Lys Asn Asn Ala Thr Val His Glu Gln Val Gly Gly Pro Ser Leu Thr 
65                  70                  75                  80  


Ser Asp Leu Gln Ala Gln Ser Lys Gly Asn Pro Glu Gln Thr Pro Val 
                85                  90                  95      


Leu Lys Pro Glu Glu Glu Ala Pro Ala Pro Glu Val Gly Ala Ser Lys 
            100                 105                 110         


Pro Glu Gly Ile Asp Ser Arg Pro Glu Thr Leu His Pro Gly Arg Pro 
        115                 120                 125             


Gln Pro Pro Ala Glu Glu Glu Leu Cys Ser Gly Lys Pro Phe Asp Ala 
    130                 135                 140                 


Phe Thr Asp Leu Lys Asn Gly Ser Leu Phe Ala Phe Arg Gly Gln Tyr 
145                 150                 155                 160 


Cys Tyr Glu Leu Asp Glu Lys Ala Val Arg Pro Gly Tyr Pro Lys Leu 
                165                 170                 175     


Ile Arg Asp Val Trp Gly Ile Glu Gly Pro Ile Asp Ala Ala Phe Thr 
            180                 185                 190         


Arg Ile Asn Cys Gln Gly Lys Thr Tyr Leu Phe Lys Gly Ser Gln Tyr 
        195                 200                 205             


Trp Arg Phe Glu Asp Gly Val Leu Asp Pro Asp Tyr Pro Arg Asn Ile 
    210                 215                 220                 


Ser Asp Gly Phe Asp Gly Ile Pro Asp Asn Val Asp Ala Ala Leu Ala 
225                 230                 235                 240 


Leu Pro Ala His Ser Tyr Ser Gly Arg Glu Arg Val Tyr Phe Phe Lys 
                245                 250                 255     


Gly Lys Gln Tyr Trp Glu Tyr Gln Phe Gln His Gln Pro Ser Gln Glu 
            260                 265                 270         


Glu Cys Glu Gly Ser Ser Leu Ser Ala Val Phe Glu His Phe Ala Met 
        275                 280                 285             


Met Gln Arg Asp Ser Trp Glu Asp Ile Phe Glu Leu Leu Phe Trp Gly 
    290                 295                 300                 


Arg Thr Ser Ala Gly Thr Arg Gln Pro Gln Phe Ile Ser Arg Asp Trp 
305                 310                 315                 320 


His Gly Val Pro Gly Gln Val Asp Ala Ala Met Ala Gly Arg Ile Tyr 
                325                 330                 335     


Ile Ser Gly Met Ala Pro Arg Pro Ser Leu Ala Lys Lys Gln Arg Phe 
            340                 345                 350         


Arg His Arg Asn Arg Lys Gly Tyr Arg Ser Gln Arg Gly His Ser Arg 
        355                 360                 365             


Gly Arg Asn Gln Asn Ser Arg Arg Pro Ser Arg Ala Met Trp Leu Ser 
    370                 375                 380                 


Leu Phe Ser Ser Glu Glu Ser Asn Leu Gly Ala Asn Asn Tyr Asp Asp 
385                 390                 395                 400 


Tyr Arg Met Asp Trp Leu Val Pro Ala Thr Cys Glu Pro Ile Gln Ser 
                405                 410                 415     


Val Phe Phe Phe Ser Gly Asp Lys Tyr Tyr Arg Val Asn Leu Arg Thr 
            420                 425                 430         


Arg Arg Val Asp Thr Val Asp Pro Pro Tyr Pro Arg Ser Ile Ala Gln 
        435                 440                 445             


Tyr Trp Leu Gly Cys Pro Ala Pro Gly His Leu 
    450                 455                 


<210>  1962
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  1962

Ala Val Trp Gln Phe Arg Lys Met Ile Lys Cys Val Ile Pro Gly Ser 
1               5                   10                  15      


Asp Pro Phe Leu Glu Tyr Asn Asn Tyr Gly Cys Tyr Cys Gly Leu Gly 
            20                  25                  30          


Gly Ser Gly Thr Pro Val Asp Glu Leu Asp Lys Cys Cys Gln Thr His 
        35                  40                  45              


Asp Asn Cys Tyr Asp Gln Ala Lys Lys Leu Asp Ser Cys Lys Phe Leu 
    50                  55                  60                  


Leu Asp Asn Pro Tyr Thr His Thr Tyr Ser Tyr Ser Cys Ser Gly Ser 
65                  70                  75                  80  


Ala Ile Thr Cys Ser Ser Lys Asn Lys Glu Cys Glu Ala Phe Ile Cys 
                85                  90                  95      


Asn Cys Asp Arg Asn Ala Ala Ile Cys Phe Ser Lys Ala Pro Tyr Asn 
            100                 105                 110         


Lys Ala His Lys Asn Leu Asp Thr Lys Lys Tyr Cys Gln Ser 
        115                 120                 125     


<210>  1963
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  1963

Ala Arg Pro Cys Ile Pro Lys Ser Phe Gly Tyr Ser Ser Val Val Cys 
1               5                   10                  15      


Val Cys Asn Ala Thr Tyr Cys Asp Ser Phe Asp Pro Pro Thr Phe Pro 
            20                  25                  30          


Ala Leu Gly Thr Phe Ser Arg Tyr Glu Ser Thr Arg Ser Gly Arg Arg 
        35                  40                  45              


Met Glu Leu Ser Met Gly Pro Ile Gln Ala Asn His Thr Gly Thr Gly 
    50                  55                  60                  


Leu Leu Leu Thr Leu Gln Pro Glu Gln Lys Phe Gln Lys Val Lys Gly 
65                  70                  75                  80  


Phe Gly Gly Ala Met Thr Asp Ala Ala Ala Leu Asn Ile Leu Ala Leu 
                85                  90                  95      


Ser Pro Pro Ala Gln Asn Leu Leu Leu Lys Ser Tyr Phe Ser Glu Glu 
            100                 105                 110         


Gly Ile Gly Tyr Asn Ile Ile Arg Val Pro Met Ala Ser Cys Asp Phe 
        115                 120                 125             


Ser Ile Arg Thr Tyr Thr Tyr Ala Asp Thr Pro Asp Asp Phe Gln Leu 
    130                 135                 140                 


His Asn Phe Ser Leu Pro Glu Glu Asp Thr Lys Leu Lys Ile Pro Leu 
145                 150                 155                 160 


Ile His Arg Ala Leu Gln Leu Ala Gln Arg Pro Val Ser Leu Leu Ala 
                165                 170                 175     


Ser Pro Trp Thr Ser Pro Thr Trp Leu Lys Thr Asn Gly Ala Val Asn 
            180                 185                 190         


Gly Lys Gly Ser Leu Lys Gly Gln Pro Gly Asp Ile Tyr His Gln Thr 
        195                 200                 205             


Trp Ala Arg Tyr Phe Val Lys Phe Leu Asp Ala Tyr Ala Glu His Lys 
    210                 215                 220                 


Leu Gln Phe Trp Ala Val Thr Ala Glu Asn Glu Pro Ser Ala Gly Leu 
225                 230                 235                 240 


Leu Ser Gly Tyr Pro Phe Gln Cys Leu Gly Phe Thr Pro Glu His Gln 
                245                 250                 255     


Arg Asp Phe Ile Ala Arg Asp Leu Gly Pro Thr Leu Ala Asn Ser Thr 
            260                 265                 270         


His His Asn Val Arg Leu Leu Met Leu Asp Asp Gln Arg Leu Leu Leu 
        275                 280                 285             


Pro His Trp Ala Lys Val Val Leu Thr Asp Pro Glu Ala Ala Lys Tyr 
    290                 295                 300                 


Val His Gly Ile Ala Val His Trp Tyr Leu Asp Phe Leu Ala Pro Ala 
305                 310                 315                 320 


Lys Ala Thr Leu Gly Glu Thr His Arg Leu Phe Pro Asn Thr Met Leu 
                325                 330                 335     


Phe Ala Ser Glu Ala Cys Val Gly Ser Lys Phe Trp Glu Gln Ser Val 
            340                 345                 350         


Arg Leu Gly Ser Trp Asp Arg Gly Met Gln Tyr Ser His Ser Ile Ile 
        355                 360                 365             


Thr Asn Leu Leu Tyr His Val Val Gly Trp Thr Asp Trp Asn Leu Ala 
    370                 375                 380                 


Leu Asn Pro Glu Gly Gly Pro Asn Trp Val Arg Asn Phe Val Asp Ser 
385                 390                 395                 400 


Pro Ile Ile Val Asp Ile Thr Lys Asp Thr Phe Tyr Lys Gln Pro Met 
                405                 410                 415     


Phe Tyr His Leu Gly His Phe Ser Lys Phe Ile Pro Glu Gly Ser Gln 
            420                 425                 430         


Arg Val Gly Leu Val Ala Ser Gln Lys Asn Asp Leu Asp Ala Val Ala 
        435                 440                 445             


Leu Met His Pro Asp Gly Ser Ala Val Val Val Val Leu Asn Arg Ser 
    450                 455                 460                 


Ser Lys Asp Val Pro Leu Thr Ile Lys Asp Pro Ala Val Gly Phe Leu 
465                 470                 475                 480 


Glu Thr Ile Ser Pro Gly Tyr Ser Ile His Thr Tyr Leu Trp Arg Arg 
                485                 490                 495     


Gln 
    


<210>  1964
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  1964

Gln Pro Pro Arg Arg Tyr Thr Pro Asp Trp Pro Ser Leu Asp Ser Arg 
1               5                   10                  15      


Pro Leu Pro Ala Trp Phe Asp Glu Ala Lys Phe Gly Val Phe Ile His 
            20                  25                  30          


Trp Gly Val Phe Ser Val Pro Ala Trp Gly Ser Glu Trp Phe Trp Trp 
        35                  40                  45              


His Trp Gln Gly Glu Gly Arg Pro Gln Tyr Gln Arg Phe Met Arg Asp 
    50                  55                  60                  


Asn Tyr Pro Pro Gly Phe Ser Tyr Ala Asp Phe Gly Pro Gln Phe Thr 
65                  70                  75                  80  


Ala Arg Phe Phe His Pro Glu Glu Trp Ala Asp Leu Phe Gln Ala Ala 
                85                  90                  95      


Gly Ala Lys Tyr Val Val Leu Thr Thr Lys His His Glu Gly Phe Thr 
            100                 105                 110         


Asn Trp Pro Ser Pro Val Ser Trp Asn Trp Asn Ser Lys Asp Val Gly 
        115                 120                 125             


Pro His Arg Asp Leu Val Gly Glu Leu Gly Thr Ala Leu Arg Lys Arg 
    130                 135                 140                 


Asn Ile Arg Tyr Gly Leu Tyr His Ser Leu Leu Glu Trp Phe His Pro 
145                 150                 155                 160 


Leu Tyr Leu Leu Asp Lys Lys Asn Gly Phe Lys Thr Gln His Phe Val 
                165                 170                 175     


Ser Ala Lys Thr Met Pro Glu Leu Tyr Asp Leu Val Asn Ser Tyr Lys 
            180                 185                 190         


Pro Asp Leu Ile Trp Ser Asp Gly Glu Trp Glu Cys Pro Asp Thr Tyr 
        195                 200                 205             


Trp Asn Ser Thr Asn Phe Leu Ser Trp Leu Tyr Asn Asp Ser Pro Val 
    210                 215                 220                 


Lys Asp Glu Val Val Val Asn Asp Arg Trp Gly Gln Asn Cys Ser Cys 
225                 230                 235                 240 


His His Gly Gly Tyr Tyr Asn Cys Glu Asp Lys Phe Lys Pro Gln Ser 
                245                 250                 255     


Leu Pro Asp His Lys Trp Glu Met Cys Thr Ser Ile Asp Lys Phe Ser 
            260                 265                 270         


Trp Gly Tyr Arg Arg Asp Met Ala Leu Ser Asp Val Thr Glu Glu Ser 
        275                 280                 285             


Glu Ile Ile Ser Glu Leu Val Gln Thr Val Ser Leu Gly Gly Asn Tyr 
    290                 295                 300                 


Leu Leu Asn Ile Gly Pro Thr Lys Asp Gly Leu Ile Val Pro Ile Phe 
305                 310                 315                 320 


Gln Glu Arg Leu Leu Ala Val Gly Lys Trp Leu Ser Ile Asn Gly Glu 
                325                 330                 335     


Ala Ile Tyr Ala Ser Lys Pro Trp Arg Val Gln Trp Glu Lys Asn Thr 
            340                 345                 350         


Thr Ser Val Trp Tyr Thr Ser Lys Gly Ser Ala Val Tyr Ala Ile Phe 
        355                 360                 365             


Leu His Trp Pro Glu Asn Gly Val Leu Asn Leu Glu Ser Pro Ile Thr 
    370                 375                 380                 


Thr Ser Thr Thr Lys Ile Thr Met Leu Gly Ile Gln Gly Asp Leu Lys 
385                 390                 395                 400 


Trp Ser Thr Asp Pro Asp Lys Gly Leu Phe Ile Ser Leu Pro Gln Leu 
                405                 410                 415     


Pro Pro Ser Ala Val Pro Ala Glu Phe Ala Trp Thr Ile Lys Leu Thr 
            420                 425                 430         


Gly Val Lys 
        435 


<210>  1965
<211>  345
<212>  PRT
<213>  Homo Sapiens

<400>  1965

Ala Met Val Ser Glu Phe Leu Lys Gln Ala Trp Phe Ile Glu Asn Glu 
1               5                   10                  15      


Glu Gln Glu Tyr Val Gln Thr Val Lys Ser Ser Lys Gly Gly Pro Gly 
            20                  25                  30          


Ser Ala Val Ser Pro Tyr Pro Thr Phe Asn Pro Ser Ser Asp Val Ala 
        35                  40                  45              


Ala Leu His Lys Ala Ile Met Val Lys Gly Val Asp Glu Ala Thr Ile 
    50                  55                  60                  


Ile Asp Ile Leu Thr Lys Arg Asn Asn Ala Gln Arg Gln Gln Ile Lys 
65                  70                  75                  80  


Ala Ala Tyr Leu Gln Glu Thr Gly Lys Pro Leu Asp Glu Thr Leu Lys 
                85                  90                  95      


Lys Ala Leu Thr Gly His Leu Glu Glu Val Val Leu Ala Leu Leu Lys 
            100                 105                 110         


Thr Pro Ala Gln Phe Asp Ala Asp Glu Leu Arg Ala Ala Met Lys Gly 
        115                 120                 125             


Leu Gly Thr Asp Glu Asp Thr Leu Ile Glu Ile Leu Ala Ser Arg Thr 
    130                 135                 140                 


Asn Lys Glu Ile Arg Asp Ile Asn Arg Val Tyr Arg Glu Glu Leu Lys 
145                 150                 155                 160 


Arg Asp Leu Ala Lys Asp Ile Thr Ser Asp Thr Ser Gly Asp Phe Arg 
                165                 170                 175     


Asn Ala Leu Leu Ser Leu Ala Lys Gly Asp Arg Ser Glu Asp Phe Gly 
            180                 185                 190         


Val Asn Glu Asp Leu Ala Asp Ser Asp Ala Arg Ala Leu Tyr Glu Ala 
        195                 200                 205             


Gly Glu Arg Arg Lys Gly Thr Asp Val Asn Val Phe Asn Thr Ile Leu 
    210                 215                 220                 


Thr Thr Arg Ser Tyr Pro Gln Leu Arg Arg Val Phe Gln Lys Tyr Thr 
225                 230                 235                 240 


Lys Tyr Ser Lys His Asp Met Asn Lys Val Leu Asp Leu Glu Leu Lys 
                245                 250                 255     


Gly Asp Ile Glu Lys Cys Leu Thr Ala Ile Val Lys Cys Ala Thr Ser 
            260                 265                 270         


Lys Pro Ala Phe Phe Ala Glu Lys Leu His Gln Ala Met Lys Gly Val 
        275                 280                 285             


Gly Thr Arg His Lys Ala Leu Ile Arg Ile Met Val Ser Arg Ser Glu 
    290                 295                 300                 


Ile Asp Met Asn Asp Ile Lys Ala Phe Tyr Gln Lys Met Tyr Gly Ile 
305                 310                 315                 320 


Ser Leu Cys Gln Ala Ile Leu Asp Glu Thr Lys Gly Asp Tyr Glu Lys 
                325                 330                 335     


Ile Leu Val Ala Leu Cys Gly Gly Asn 
            340                 345 


<210>  1966
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  1966

Asp Ser Trp Met Glu Glu Val Ile Lys Leu Cys Gly Arg Glu Leu Val 
1               5                   10                  15      


Arg Ala Gln Ile Ala Ile Cys Gly Met Ser Thr Trp Ser Lys Arg Ser 
            20                  25                  30          


Leu Ser Gln Glu Asp Ala Pro Gln Thr Pro Arg Pro Val Ala Glu Ile 
        35                  40                  45              


Val Pro Ser Phe Ile Asn Lys Asp Thr Glu Thr Ile Asn Met Met Ser 
    50                  55                  60                  


Glu Phe Val Ala Asn Leu Pro Gln Glu Leu Lys Leu Thr Leu Ser Glu 
65                  70                  75                  80  


Met Gln Pro Ala Leu Pro Gln Leu Gln Gln His Val Pro Val Leu Lys 
                85                  90                  95      


Asp Ser Ser Leu Leu Phe Glu Glu Phe Lys Lys Leu Ile Arg Asn Arg 
            100                 105                 110         


Gln Ser Glu Ala Ala Asp Ser Ser Pro Ser Glu Leu Lys Tyr Leu Gly 
        115                 120                 125             


Leu Asp Thr His Ser Arg Lys Lys Arg Gln Leu Tyr Ser Ala Leu Ala 
    130                 135                 140                 


Asn Lys Cys Cys His Val Gly Cys Thr Lys Arg Ser Leu Ala Arg Phe 
145                 150                 155                 160 


Cys 
    


<210>  1967
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  1967

Gly Ile Ile Ile Asn Leu Glu Asn Gly Glu Leu Cys Met Asn Ser Ala 
1               5                   10                  15      


Gln Cys Lys Ser Asn Cys Cys Gln His Ser Ser Ala Leu Gly Leu Ala 
            20                  25                  30          


Arg Cys Thr Ser Met Ala Ser Glu Asn Ser Glu Cys Ser Val Lys Thr 
        35                  40                  45              


Leu Tyr Gly Ile Tyr Tyr Lys Cys Pro Cys Glu Arg Gly Leu Thr Cys 
    50                  55                  60                  


Glu Gly Asp Lys Thr Ile Val Gly Ser Ile Thr Asn Thr Asn Phe Gly 
65                  70                  75                  80  


Ile Cys His Asp Ala Gly Arg Ser Lys Gln 
                85                  90  


<210>  1968
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  1968

Glu Ala Gln Thr Glu Thr Cys Thr Val Ala Pro Arg Glu Arg Gln Asn 
1               5                   10                  15      


Cys Gly Phe Pro Gly Val Thr Pro Ser Gln Cys Ala Asn Lys Gly Cys 
            20                  25                  30          


Cys Phe Asp Asp Thr Val Arg Gly Val Pro Trp Cys Phe Tyr Pro Asn 
        35                  40                  45              


Thr Ile Asp Val Pro Pro Glu Glu Glu Cys Glu Phe 
    50                  55                  60  


<210>  1969
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  1969

Lys Lys Arg Pro Lys Pro Gly Gly Trp Asn Thr Gly Gly Ser Arg Tyr 
1               5                   10                  15      


Pro Gly Gln Gly Ser Pro Gly Gly Asn Arg Tyr Pro Pro Gln Gly Gly 
            20                  25                  30          


Gly Gly Trp Gly Gln Pro His Gly Gly Gly Trp Gly Gln Pro His Gly 
        35                  40                  45              


Gly Gly Trp Gly Gln Pro His Gly Gly Gly Trp Gly Gln Pro His Gly 
    50                  55                  60                  


Gly Gly Trp Gly Gln Gly Gly Gly Thr His Ser Gln Trp Asn Lys Pro 
65                  70                  75                  80  


Ser Lys Pro Lys Thr Asn Met Lys His Met Ala Gly Ala Ala Ala Ala 
                85                  90                  95      


Gly Ala Val Val Gly Gly Leu Gly Gly Tyr Leu Leu Gly Ser Ala Met 
            100                 105                 110         


Ser Arg Pro Ile Ile His Phe Gly Ser Asp Tyr Glu Asp Arg Tyr Tyr 
        115                 120                 125             


Arg Glu Asn Met His Arg Tyr Pro Asn Gln Val Tyr Tyr Arg Pro Met 
    130                 135                 140                 


Asp Glu Tyr Ser Asn Gln Asn Asn Phe Val His Asp Cys Val Asn Ile 
145                 150                 155                 160 


Thr Ile Lys Gln His Thr Val Thr Thr Thr Thr Lys Gly Glu Asn Phe 
                165                 170                 175     


Thr Glu Thr Asp Val Lys Met Met Glu Arg Val Val Glu Gln Met Cys 
            180                 185                 190         


Ile Thr Gln Tyr Glu Arg Glu Ser Gln Ala Tyr Tyr Gln Arg Gly Ser 
        195                 200                 205             


<210>  1970
<211>  507
<212>  PRT
<213>  Homo Sapiens

<400>  1970

Val Ser Pro Thr Asp Cys Ser Ala Val Glu Pro Glu Ala Glu Lys Ala 
1               5                   10                  15      


Leu Asp Leu Ile Asn Lys Arg Arg Arg Asp Gly Tyr Leu Phe Gln Leu 
            20                  25                  30          


Leu Arg Ile Ala Asp Ala His Leu Asp Arg Val Glu Asn Thr Thr Val 
        35                  40                  45              


Tyr Tyr Leu Val Leu Asp Val Gln Glu Ser Asp Cys Ser Val Leu Ser 
    50                  55                  60                  


Arg Lys Tyr Trp Asn Asp Cys Glu Pro Pro Asp Ser Arg Arg Pro Ser 
65                  70                  75                  80  


Glu Ile Val Ile Gly Gln Cys Lys Val Ile Ala Thr Arg His Ser His 
                85                  90                  95      


Glu Ser Gln Asp Leu Arg Val Ile Asp Phe Asn Cys Thr Thr Ser Ser 
            100                 105                 110         


Val Ser Ser Ala Leu Ala Asn Thr Lys Asp Ser Pro Val Leu Ile Asp 
        115                 120                 125             


Phe Phe Glu Asp Thr Glu Arg Tyr Arg Lys Gln Ala Asn Lys Ala Leu 
    130                 135                 140                 


Glu Lys Tyr Lys Glu Glu Asn Asp Asp Phe Ala Ser Phe Arg Val Asp 
145                 150                 155                 160 


Arg Ile Glu Arg Val Ala Arg Val Arg Gly Gly Glu Gly Thr Gly Tyr 
                165                 170                 175     


Phe Val Asp Phe Ser Val Arg Asn Cys Pro Arg His His Phe Pro Arg 
            180                 185                 190         


His Pro Asn Val Phe Gly Phe Cys Arg Ala Asp Leu Phe Tyr Asp Val 
        195                 200                 205             


Glu Ala Leu Asp Leu Glu Ser Pro Lys Asn Leu Val Ile Asn Cys Glu 
    210                 215                 220                 


Val Phe Asp Pro Gln Glu His Glu Asn Ile Asn Gly Val Pro Pro His 
225                 230                 235                 240 


Leu Gly His Pro Phe His Trp Gly Gly His Glu Arg Ser Ser Thr Thr 
                245                 250                 255     


Lys Pro Pro Phe Lys Pro His Gly Ser Arg Asp His His His Pro His 
            260                 265                 270         


Lys Pro His Glu His Gly Pro Pro Pro Pro Pro Asp Glu Arg Asp His 
        275                 280                 285             


Ser His Gly Pro Pro Leu Pro Gln Gly Pro Pro Pro Leu Leu Pro Met 
    290                 295                 300                 


Ser Cys Ser Ser Cys Gln His Ala Thr Phe Gly Thr Asn Gly Ala Gln 
305                 310                 315                 320 


Arg His Ser His Asn Asn Asn Ser Ser Asp Leu His Pro His Lys His 
                325                 330                 335     


His Ser His Glu Gln His Pro His Gly His His Pro His Ala His His 
            340                 345                 350         


Pro His Glu His Asp Thr His Arg Gln His Pro His Gly His His Pro 
        355                 360                 365             


His Gly His His Pro His Gly His His Pro His Gly His His Pro His 
    370                 375                 380                 


Gly His His Pro His Cys His Asp Phe Gln Asp Tyr Gly Pro Cys Asp 
385                 390                 395                 400 


Pro Pro Pro His Asn Gln Gly His Cys Cys His Gly His Gly Pro Pro 
                405                 410                 415     


Pro Gly His Leu Arg Arg Arg Gly Pro Gly Lys Gly Pro Arg Pro Phe 
            420                 425                 430         


His Cys Arg Gln Ile Gly Ser Val Tyr Arg Leu Pro Pro Leu Arg Lys 
        435                 440                 445             


Gly Glu Val Leu Pro Leu Pro Glu Ala Asn Phe Pro Ser Phe Pro Leu 
    450                 455                 460                 


Pro His His Lys His Pro Leu Lys Pro Asp Asn Gln Pro Phe Pro Gln 
465                 470                 475                 480 


Ser Val Ser Glu Ser Cys Pro Gly Lys Phe Lys Ser Gly Phe Pro Gln 
                485                 490                 495     


Val Ser Met Phe Phe Thr His Thr Phe Pro Lys 
            500                 505         


<210>  1971
<211>  373
<212>  PRT
<213>  Homo Sapiens

<400>  1971

Leu Arg Pro Val Leu Pro Thr Gln Ser Ala His Asp Pro Pro Ala Val 
1               5                   10                  15      


His Leu Ser Asn Gly Pro Gly Gln Glu Pro Ile Ala Val Met Thr Phe 
            20                  25                  30          


Asp Leu Thr Lys Ile Thr Lys Thr Ser Ser Ser Phe Glu Val Arg Thr 
        35                  40                  45              


Trp Asp Pro Glu Gly Val Ile Phe Tyr Gly Asp Thr Asn Pro Lys Asp 
    50                  55                  60                  


Asp Trp Phe Met Leu Gly Leu Arg Asp Gly Arg Pro Glu Ile Gln Leu 
65                  70                  75                  80  


His Asn His Trp Ala Gln Leu Thr Val Gly Ala Gly Pro Arg Leu Asp 
                85                  90                  95      


Asp Gly Arg Trp His Gln Val Glu Val Lys Met Glu Gly Asp Ser Val 
            100                 105                 110         


Leu Leu Glu Val Asp Gly Glu Glu Val Leu Arg Leu Arg Gln Val Ser 
        115                 120                 125             


Gly Pro Leu Thr Ser Lys Arg His Pro Ile Met Arg Ile Ala Leu Gly 
    130                 135                 140                 


Gly Leu Leu Phe Pro Ala Ser Asn Leu Arg Leu Pro Leu Val Pro Ala 
145                 150                 155                 160 


Leu Asp Gly Cys Leu Arg Arg Asp Ser Trp Leu Asp Lys Gln Ala Glu 
                165                 170                 175     


Ile Ser Ala Ser Ala Pro Thr Ser Leu Arg Ser Cys Asp Val Glu Ser 
            180                 185                 190         


Asn Pro Gly Ile Phe Leu Pro Pro Gly Thr Gln Ala Glu Phe Asn Leu 
        195                 200                 205             


Arg Asp Ile Pro Gln Pro His Ala Glu Pro Trp Ala Phe Ser Leu Asp 
    210                 215                 220                 


Leu Gly Leu Lys Gln Ala Ala Gly Ser Gly His Leu Leu Ala Leu Gly 
225                 230                 235                 240 


Thr Pro Glu Asn Pro Ser Trp Leu Ser Leu His Leu Gln Asp Gln Lys 
                245                 250                 255     


Val Val Leu Ser Ser Gly Ser Gly Pro Gly Leu Asp Leu Pro Leu Val 
            260                 265                 270         


Leu Gly Leu Pro Leu Gln Leu Lys Leu Ser Met Ser Arg Val Val Leu 
        275                 280                 285             


Ser Gln Gly Ser Lys Met Lys Ala Leu Ala Leu Pro Pro Leu Gly Leu 
    290                 295                 300                 


Ala Pro Leu Leu Asn Leu Trp Ala Lys Pro Gln Gly Arg Leu Phe Leu 
305                 310                 315                 320 


Gly Ala Leu Pro Gly Glu Asp Ser Ser Thr Ser Phe Cys Leu Asn Gly 
                325                 330                 335     


Leu Trp Ala Gln Gly Gln Arg Leu Asp Val Asp Gln Ala Leu Asn Arg 
            340                 345                 350         


Ser His Glu Ile Trp Thr His Ser Cys Pro Gln Ser Pro Gly Asn Gly 
        355                 360                 365             


Thr Asp Ala Ser His 
    370             


<210>  1972
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  1972

Ala Asn Ser Ser Gly Arg Trp Trp Gly Ile Val Asn Val Ala Ser Ser 
1               5                   10                  15      


Thr Asn Leu Leu Thr Asp Ser Lys Ser Leu Gln Leu Val Leu Glu Pro 
            20                  25                  30          


Ser Leu Gln Leu Leu Ser Arg Lys Gln Arg Arg Leu Ile Arg Gln Asn 
        35                  40                  45              


Pro Gly Ile Leu His Ser Val Ser Gly Gly Leu Gln Ser Ala Val Arg 
    50                  55                  60                  


Glu Cys Lys Trp Gln Phe Arg Asn Arg Arg Trp Asn Cys Pro Thr Ala 
65                  70                  75                  80  


Pro Gly Pro His Leu Phe Gly Lys Ile Val Asn Arg Gly Cys Arg Glu 
                85                  90                  95      


Thr Ala Phe Ile Phe Ala Ile Thr Ser Ala Gly Val Thr His Ser Val 
            100                 105                 110         


Ala Arg Ser Cys Ser Glu Gly Ser Ile Glu Ser Cys Thr Cys Asp Tyr 
        115                 120                 125             


Arg Arg Arg Gly Pro Gly Gly Pro Asp Trp His Trp Gly Gly Cys Ser 
    130                 135                 140                 


Asp Asn Ile Asp Phe Gly Arg Leu Phe Gly Arg Glu Phe Val Asp Ser 
145                 150                 155                 160 


Gly Glu Lys Gly Arg Asp Leu Arg Phe Leu Met Asn Leu His Asn Asn 
                165                 170                 175     


Glu Ala Gly Arg Thr Thr Val Phe Ser Glu Met Arg Gln Glu Cys Lys 
            180                 185                 190         


Cys His Gly Met Ser Gly Ser Cys Thr Val Arg Thr Cys Trp Met Arg 
        195                 200                 205             


Leu Pro Thr Leu Arg Ala Val Gly Asp Val Leu Arg Asp Arg Phe Asp 
    210                 215                 220                 


Gly Ala Ser Arg Val Leu Tyr Gly Asn Arg Gly Ser Asn Arg Ala Ser 
225                 230                 235                 240 


Arg Ala Glu Leu Leu Arg Leu Glu Pro Glu Asp Pro Ala His Lys Pro 
                245                 250                 255     


Pro Ser Pro His Asp Leu Val Tyr Phe Glu Lys Ser Pro Asn Phe Cys 
            260                 265                 270         


Thr Tyr Ser Gly Arg Leu Gly Thr Ala Gly Thr Ala Gly Arg Ala Cys 
        275                 280                 285             


Asn Ser Ser Ser Pro Ala Leu Asp Gly Cys Glu Leu Leu Cys Cys Gly 
    290                 295                 300                 


Arg Gly His Arg Thr Arg Thr Gln Arg Val Thr Glu Arg Cys Asn Cys 
305                 310                 315                 320 


Thr Phe His Trp Cys Cys His Val Ser Cys Arg Asn Cys Thr His Thr 
                325                 330                 335     


Arg Val Leu His Glu Cys Leu 
            340             


<210>  1973
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  1973

Gln Tyr Ser Ser Asn Thr Gln Gln Gly Arg Thr Ser Ile Val His Leu 
1               5                   10                  15      


Phe Glu Trp Arg Trp Val Asp Ile Ala Leu Glu Cys Glu Arg Tyr Leu 
            20                  25                  30          


Ala Pro Lys Gly Phe Gly Gly Val Gln Val Ser Pro Pro Asn Glu Asn 
        35                  40                  45              


Val Ala Ile His Asn Pro Phe Arg Pro Trp Trp Glu Arg Tyr Gln Pro 
    50                  55                  60                  


Val Ser Tyr Lys Leu Cys Thr Arg Ser Gly Asn Glu Asp Glu Phe Arg 
65                  70                  75                  80  


Asn Met Val Thr Arg Cys Asn Asn Val Gly Val Arg Ile Tyr Val Asp 
                85                  90                  95      


Ala Val Ile Asn His Met Cys Gly Asn Ala Val Ser Ala Gly Thr Ser 
            100                 105                 110         


Ser Thr Cys Gly Ser Tyr Phe Asn Pro Gly Ser Arg Asp Phe Pro Ala 
        115                 120                 125             


Val Pro Tyr Ser Gly Trp Asp Phe Asn Asp Gly Lys Cys Lys Thr Gly 
    130                 135                 140                 


Ser Gly Asp Ile Glu Asn Tyr Asn Asp Ala Thr Gln Val Arg Asp Cys 
145                 150                 155                 160 


Arg Leu Ser Gly Leu Leu Asp Leu Ala Leu Gly Lys Asp Tyr Val Arg 
                165                 170                 175     


Ser Lys Ile Ala Glu Tyr Met Asn His Leu Ile Asp Ile Gly Val Ala 
            180                 185                 190         


Gly Phe Arg Ile Asp Ala Ser Lys His Met Trp Pro Gly Asp Ile Lys 
        195                 200                 205             


Ala Ile Leu Asp Lys Leu His Asn Leu Asn Ser Asn Trp Phe Pro Glu 
    210                 215                 220                 


Gly Ser Lys Pro Phe Ile Tyr Gln Glu Val Ile Asp Leu Gly Gly Glu 
225                 230                 235                 240 


Pro Ile Lys Ser Ser Asp Tyr Phe Gly Asn Gly Arg Val Thr Glu Phe 
                245                 250                 255     


Lys Tyr Gly Ala Lys Leu Gly Thr Val Ile Arg Lys Trp Asn Gly Glu 
            260                 265                 270         


Lys Met Ser Tyr Leu Lys Asn Trp Gly Glu Gly Trp Gly Phe Met Pro 
        275                 280                 285             


Ser Asp Arg Ala Leu Val Phe Val Asp Asn His Asp Asn Gln Arg Gly 
    290                 295                 300                 


His Gly Ala Gly Gly Ala Ser Ile Leu Thr Phe Trp Asp Ala Arg Leu 
305                 310                 315                 320 


Tyr Lys Met Ala Val Gly Phe Met Leu Ala His Pro Tyr Gly Phe Thr 
                325                 330                 335     


Arg Val Met Ser Ser Tyr Arg Trp Pro Arg Tyr Phe Glu Asn Gly Lys 
            340                 345                 350         


Asp Val Asn Asp Trp Val Gly Pro Pro Asn Asp Asn Gly Val Thr Lys 
        355                 360                 365             


Glu Val Thr Ile Asn Pro Asp Thr Thr Cys Gly Asn Asp Trp Val Cys 
    370                 375                 380                 


Glu His Arg Trp Arg Gln Ile Arg Asn Met Val Asn Phe Arg Asn Val 
385                 390                 395                 400 


Val Asp Gly Gln Pro Phe Thr Asn Trp Tyr Asp Asn Gly Ser Asn Gln 
                405                 410                 415     


Val Ala Phe Gly Arg Gly Asn Arg Gly Phe Ile Val Phe Asn Asn Asp 
            420                 425                 430         


Asp Trp Thr Phe Ser Leu Thr Leu Gln Thr Gly Leu Pro Ala Gly Thr 
        435                 440                 445             


Tyr Cys Asp Val Ile Ser Gly Asp Lys Ile Asn Gly Asn Cys Thr Gly 
    450                 455                 460                 


Ile Lys Ile Tyr Val Ser Asp Asp Gly Lys Ala His Phe Ser Ile Ser 
465                 470                 475                 480 


Asn Ser Ala Glu Asp Pro Phe Ile Ala Ile His Ala Glu Ser Lys Leu 
                485                 490                 495     


<210>  1974
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  1974

Val Ala Ala Lys Trp Lys Asp Asp Val Ile Lys Leu Cys Gly Arg Glu 
1               5                   10                  15      


Leu Val Arg Ala Gln Ile Ala Ile Cys Gly Met Ser Thr Trp Ser Lys 
            20                  25                  30          


Arg Ser Leu Ser Gln Glu Asp Ala Pro Gln Thr Pro Arg Pro Val Ala 
        35                  40                  45              


Glu Ile Val Pro Ser Phe Ile Asn Lys Asp Thr Glu Thr Ile Ile Ile 
    50                  55                  60                  


Met Leu Glu Phe Ile Ala Asn Leu Pro Pro Glu Leu Lys Ala Ala Leu 
65                  70                  75                  80  


Ser Glu Arg Gln Pro Ser Leu Pro Glu Leu Gln Gln Tyr Val Pro Ala 
                85                  90                  95      


Leu Lys Asp Ser Asn Leu Ser Phe Glu Glu Phe Lys Lys Leu Ile Arg 
            100                 105                 110         


Asn Arg Gln Ser Glu Ala Ala Asp Ser Asn Pro Ser Glu Leu Lys Tyr 
        115                 120                 125             


Leu Gly Leu Asp Thr His Ser Gln Lys Lys Arg Arg Pro Tyr Val Ala 
    130                 135                 140                 


Leu Phe Glu Lys Cys Cys Leu Ile Gly Cys Thr Lys Arg Ser Leu Ala 
145                 150                 155                 160 


Lys Tyr Cys 
            


<210>  1975
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  1975

Gln Glu His Pro Leu His Gly Cys Ser Ala Ser Asn Ser Ser Glu Val 
1               5                   10                  15      


Asp Gly Gly Glu Asn Met Thr Trp Ala Gly Ala Arg Pro Thr Leu Gly 
            20                  25                  30          


Pro Gly Asn Arg Ser Leu Ala Gly Gln Ser Gly Gln Gly Lys Pro Arg 
        35                  40                  45              


Gly Gln Pro Asn Thr 
    50              


<210>  1976
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  1976

Met Trp Ser Thr Arg Ser Pro Asn Ser Thr Ala Trp Pro Leu Ser Leu 
1               5                   10                  15      


Glu Pro Asp Pro Gly Met Ala Ser Ala Ser Thr Thr Met His Thr Thr 
            20                  25                  30          


Thr Ile Ala Glu Pro Asp Pro Gly Met Ser Gly Trp Pro Asp Gly Arg 
        35                  40                  45              


Met Glu Thr Ser Thr Pro Thr Ile Met 
    50                  55          


<210>  1977
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  1977

Phe Thr Tyr Phe Val Ile Leu Ala Glu Asn Gly Phe Leu Pro Ile His 
1               5                   10                  15      


Leu Leu Gly Leu Arg Val Asp Trp Asp Asp Arg Trp Ile Asn Asp Val 
            20                  25                  30          


Glu Asp Ser Tyr Gly Gln Gln Trp Thr Tyr Glu Gln Arg Lys Ile Val 
        35                  40                  45              


Glu Phe Thr Cys 
    50          


<210>  1978
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  1978

Glu Phe Lys Pro Thr Tyr Gln Asp Arg Val Ala Pro Pro Gly Leu Thr 
1               5                   10                  15      


Gln Ile Pro Gln Ile Gln Lys Thr Glu Ile Ser Phe Arg Pro Asn Asp 
            20                  25                  30          


Pro Lys Ser Tyr Glu Ala Tyr Val Leu Asn Ile Val Arg Phe Leu Glu 
        35                  40                  45              


Lys Tyr Lys Asp Ser Ala Gln Arg Asp Asp Met Ile Phe Glu Asp Cys 
    50                  55                  60                  


Gly Asp Val Pro Ser Glu Pro Lys Glu Arg Gly Asp Phe Asn His Glu 
65                  70                  75                  80  


Arg Gly Glu Arg Lys Val Cys Arg Phe Lys Leu Glu Trp Leu Gly Asn 
                85                  90                  95      


Cys Ser Gly Leu Asn Asp Glu Thr Tyr Gly Tyr Lys Glu Gly Lys Pro 
            100                 105                 110         


Cys Ile Ile Ile Lys Leu Asn Arg Val Leu Gly Phe Lys Pro Lys Pro 
        115                 120                 125             


Pro Lys Asn Glu Ser Leu Glu Thr Tyr Pro Val Met Lys Tyr Asn Pro 
    130                 135                 140                 


Asn Val Leu Pro Val Gln Cys Thr Gly Lys Arg Asp Glu Asp Lys Asp 
145                 150                 155                 160 


Lys Val Gly Asn Val Glu Tyr Phe Gly Leu Gly Asn Ser Pro Gly Phe 
                165                 170                 175     


Pro Leu Gln Tyr Tyr Pro Tyr Tyr Gly Lys Leu Leu Gln Pro Lys Tyr 
            180                 185                 190         


Leu Gln Pro Leu Leu Ala Val Gln Phe Thr Asn Leu Thr Met Asp Thr 
        195                 200                 205             


Glu Ile Arg Ile Glu Cys Lys Ala Tyr Gly Glu Asn Ile Gly Tyr Ser 
    210                 215                 220                 


Glu Lys Asp Arg Phe Gln Gly Arg Phe Asp Val Lys Ile Glu Val Lys 
225                 230                 235                 240 


Ser 
    


<210>  1979
<211>  657
<212>  PRT
<213>  Homo Sapiens

<400>  1979

Met Pro Val Asp Asn Arg Asn His Asn Glu Gly Met Val Thr Arg Cys 
1               5                   10                  15      


Ile Ile Glu Val Leu Ser Asn Ala Leu Ser Lys Ser Ser Ala Pro Pro 
            20                  25                  30          


Ile Thr Pro Glu Cys Arg Gln Val Leu Lys Thr Ser Arg Lys Asp Val 
        35                  40                  45              


Lys Asp Lys Glu Thr Thr Glu Asn Glu Asn Thr Lys Phe Glu Val Arg 
    50                  55                  60                  


Leu Leu Arg Asp Pro Ala Asp Ala Ser Glu Ala His Glu Ser Ser Ser 
65                  70                  75                  80  


Arg Gly Glu Ala Gly Ala Pro Gly Glu Glu Asp Ile Gln Gly Pro Thr 
                85                  90                  95      


Lys Ala Asp Thr Glu Lys Trp Ala Glu Gly Gly Gly His Ser Arg Glu 
            100                 105                 110         


Arg Ala Asp Glu Pro Gln Trp Ser Leu Tyr Pro Ser Asp Ser Gln Val 
        115                 120                 125             


Ser Glu Glu Val Lys Thr Arg His Ser Glu Lys Ser Gln Arg Glu Asp 
    130                 135                 140                 


Glu Glu Glu Glu Glu Gly Glu Asn Tyr Gln Lys Gly Glu Arg Gly Glu 
145                 150                 155                 160 


Asp Ser Ser Glu Glu Lys His Leu Glu Glu Pro Gly Glu Thr Gln Asn 
                165                 170                 175     


Ala Phe Leu Asn Glu Arg Lys Gln Ala Ser Ala Ile Lys Lys Glu Glu 
            180                 185                 190         


Leu Val Ala Arg Ser Glu Thr His Ala Ala Gly His Ser Gln Glu Lys 
        195                 200                 205             


Thr His Ser Arg Glu Lys Ser Ser Gln Glu Ser Gly Glu Glu Ala Gly 
    210                 215                 220                 


Ser Gln Glu Asn His Pro Gln Glu Ser Lys Gly Gln Pro Arg Ser Gln 
225                 230                 235                 240 


Glu Glu Ser Glu Glu Gly Glu Glu Asp Ala Thr Ser Glu Val Asp Lys 
                245                 250                 255     


Arg Arg Thr Arg Pro Arg His His His Gly Arg Ser Arg Pro Asp Arg 
            260                 265                 270         


Ser Ser Gln Gly Gly Ser Leu Pro Ser Glu Glu Lys Gly His Pro Gln 
        275                 280                 285             


Glu Glu Ser Glu Glu Ser Asn Val Ser Met Ala Ser Leu Gly Glu Lys 
    290                 295                 300                 


Arg Asp His His Ser Thr His Tyr Arg Ala Ser Glu Glu Glu Pro Glu 
305                 310                 315                 320 


Tyr Gly Glu Glu Ile Lys Gly Tyr Pro Gly Val Gln Ala Pro Glu Asp 
                325                 330                 335     


Leu Glu Trp Glu Arg Tyr Arg Gly Arg Gly Ser Glu Glu Tyr Arg Ala 
            340                 345                 350         


Pro Arg Pro Gln Ser Glu Glu Ser Trp Asp Glu Glu Asp Lys Arg Asn 
        355                 360                 365             


Tyr Pro Ser Leu Glu Leu Asp Lys Met Ala His Gly Tyr Gly Glu Glu 
    370                 375                 380                 


Ser Glu Glu Glu Arg Gly Leu Glu Pro Gly Lys Gly Arg His His Arg 
385                 390                 395                 400 


Gly Arg Gly Gly Glu Pro Arg Ala Tyr Phe Met Ser Asp Thr Arg Glu 
                405                 410                 415     


Glu Lys Arg Phe Leu Gly Glu Gly His His Arg Val Gln Glu Asn Gln 
            420                 425                 430         


Met Asp Lys Ala Arg Arg His Pro Gln Gly Ala Trp Lys Glu Leu Asp 
        435                 440                 445             


Arg Asn Tyr Leu Asn Tyr Gly Glu Glu Gly Ala Pro Gly Lys Trp Gln 
    450                 455                 460                 


Gln Gln Gly Asp Leu Gln Asp Thr Lys Glu Asn Arg Glu Glu Ala Arg 
465                 470                 475                 480 


Phe Gln Asp Lys Gln Tyr Ser Ser His His Thr Ala Glu Lys Arg Lys 
                485                 490                 495     


Arg Leu Gly Glu Leu Phe Asn Pro Tyr Tyr Asp Pro Leu Gln Trp Lys 
            500                 505                 510         


Ser Ser His Phe Glu Arg Arg Asp Asn Met Asn Asp Asn Phe Leu Glu 
        515                 520                 525             


Gly Glu Glu Glu Asn Glu Leu Thr Leu Asn Glu Lys Asn Phe Phe Pro 
    530                 535                 540                 


Glu Tyr Asn Tyr Asp Trp Trp Glu Lys Lys Pro Phe Ser Glu Asp Val 
545                 550                 555                 560 


Asn Trp Gly Tyr Glu Lys Arg Asn Leu Ala Arg Val Pro Lys Leu Asp 
                565                 570                 575     


Leu Lys Arg Gln Tyr Asp Arg Val Ala Gln Leu Asp Gln Leu Leu His 
            580                 585                 590         


Tyr Arg Lys Lys Ser Ala Glu Phe Pro Asp Phe Tyr Asp Ser Glu Glu 
        595                 600                 605             


Pro Val Ser Thr His Gln Glu Ala Glu Asn Glu Lys Asp Arg Ala Asp 
    610                 615                 620                 


Gln Thr Val Leu Thr Glu Asp Glu Lys Lys Glu Leu Glu Asn Leu Ala 
625                 630                 635                 640 


Ala Met Asp Leu Glu Leu Gln Lys Ile Ala Glu Lys Phe Ser Gln Arg 
                645                 650                 655     


Gly 
    


<210>  1980
<211>  663
<212>  PRT
<213>  Homo Sapiens

<400>  1980

Leu Glu Val Pro Thr Asp Gly Asn Ala Gly Leu Leu Ala Glu Pro Gln 
1               5                   10                  15      


Ile Ala Met Phe Cys Gly Arg Leu Asn Met His Met Asn Val Gln Asn 
            20                  25                  30          


Gly Lys Trp Asp Ser Asp Pro Ser Gly Thr Lys Thr Cys Ile Asp Thr 
        35                  40                  45              


Lys Glu Gly Ile Leu Gln Tyr Cys Gln Glu Val Tyr Pro Glu Leu Gln 
    50                  55                  60                  


Ile Thr Asn Val Val Glu Ala Asn Gln Pro Val Thr Ile Gln Asn Trp 
65                  70                  75                  80  


Cys Lys Arg Gly Arg Lys Gln Cys Lys Thr His Pro His Phe Val Ile 
                85                  90                  95      


Pro Tyr Arg Cys Leu Val Gly Glu Phe Val Ser Asp Ala Leu Leu Val 
            100                 105                 110         


Pro Asp Lys Cys Lys Phe Leu His Gln Glu Arg Met Asp Val Cys Glu 
        115                 120                 125             


Thr His Leu His Trp His Thr Val Ala Lys Glu Thr Cys Ser Glu Lys 
    130                 135                 140                 


Ser Thr Asn Leu His Asp Tyr Gly Met Leu Leu Pro Cys Gly Ile Asp 
145                 150                 155                 160 


Lys Phe Arg Gly Val Glu Phe Val Cys Cys Pro Leu Ala Glu Glu Ser 
                165                 170                 175     


Asp Asn Val Asp Ser Ala Asp Ala Glu Glu Asp Asp Ser Asp Val Trp 
            180                 185                 190         


Trp Gly Gly Ala Asp Thr Asp Tyr Ala Asp Gly Ser Glu Asp Lys Val 
        195                 200                 205             


Val Glu Val Ala Glu Glu Glu Glu Val Ala Glu Val Glu Glu Glu Glu 
    210                 215                 220                 


Ala Asp Asp Asp Glu Asp Asp Glu Asp Gly Asp Glu Val Glu Glu Glu 
225                 230                 235                 240 


Ala Glu Glu Pro Tyr Glu Glu Ala Thr Glu Arg Thr Thr Ser Ile Ala 
                245                 250                 255     


Thr Thr Thr Thr Thr Thr Thr Glu Ser Val Glu Glu Val Val Arg Glu 
            260                 265                 270         


Val Cys Ser Glu Gln Ala Glu Thr Gly Pro Cys Arg Ala Met Ile Ser 
        275                 280                 285             


Arg Trp Tyr Phe Asp Val Thr Glu Gly Lys Cys Ala Pro Phe Phe Tyr 
    290                 295                 300                 


Gly Gly Cys Gly Gly Asn Arg Asn Asn Phe Asp Thr Glu Glu Tyr Cys 
305                 310                 315                 320 


Met Ala Val Cys Gly Ser Ala Ile Pro Thr Thr Ala Ala Ser Thr Pro 
                325                 330                 335     


Asp Ala Val Asp Lys Tyr Leu Glu Thr Pro Gly Asp Glu Asn Glu His 
            340                 345                 350         


Ala His Phe Gln Lys Ala Lys Glu Arg Leu Glu Ala Lys His Arg Glu 
        355                 360                 365             


Arg Met Ser Gln Val Met Arg Glu Trp Glu Glu Ala Glu Arg Gln Ala 
    370                 375                 380                 


Lys Asn Leu Pro Lys Ala Asp Lys Lys Ala Val Ile Gln His Phe Gln 
385                 390                 395                 400 


Glu Lys Val Glu Ser Leu Glu Gln Glu Ala Ala Asn Glu Arg Gln Gln 
                405                 410                 415     


Leu Val Glu Thr His Met Ala Arg Val Glu Ala Met Leu Asn Asp Arg 
            420                 425                 430         


Arg Arg Leu Ala Leu Glu Asn Tyr Ile Thr Ala Leu Gln Ala Val Pro 
        435                 440                 445             


Pro Arg Pro Arg His Val Phe Asn Met Leu Lys Lys Tyr Val Arg Ala 
    450                 455                 460                 


Glu Gln Lys Asp Arg Gln His Thr Leu Lys His Phe Glu His Val Arg 
465                 470                 475                 480 


Met Val Asp Pro Lys Lys Ala Ala Gln Ile Arg Ser Gln Val Met Thr 
                485                 490                 495     


His Leu Arg Val Ile Tyr Glu Arg Met Asn Gln Ser Leu Ser Leu Leu 
            500                 505                 510         


Tyr Asn Val Pro Ala Val Ala Glu Glu Ile Gln Asp Glu Val Asp Glu 
        515                 520                 525             


Leu Leu Gln Lys Glu Gln Asn Tyr Ser Asp Asp Val Leu Ala Asn Met 
    530                 535                 540                 


Ile Ser Glu Pro Arg Ile Ser Tyr Gly Asn Asp Ala Leu Met Pro Ser 
545                 550                 555                 560 


Leu Thr Glu Thr Lys Thr Thr Val Glu Leu Leu Pro Val Asn Gly Glu 
                565                 570                 575     


Phe Ser Leu Asp Asp Leu Gln Pro Trp His Ser Phe Gly Ala Asp Ser 
            580                 585                 590         


Val Pro Ala Asn Thr Glu Asn Glu Val Glu Pro Val Asp Ala Arg Pro 
        595                 600                 605             


Ala Ala Asp Arg Gly Leu Thr Thr Arg Pro Gly Ser Gly Leu Thr Asn 
    610                 615                 620                 


Ile Lys Thr Glu Glu Ile Ser Glu Val Lys Met Asp Ala Glu Phe Arg 
625                 630                 635                 640 


His Asp Ser Gly Tyr Glu Val His His Gln Lys Leu Val Phe Phe Ala 
                645                 650                 655     


Glu Asp Val Gly Ser Asn Lys 
            660             


<210>  1981
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  1981

Gln Ala Phe His Leu Gly Lys Cys Pro Asn Pro Pro Val Gln Glu Asn 
1               5                   10                  15      


Phe Asp Val Asn Lys Tyr Leu Gly Arg Trp Tyr Glu Ile Glu Lys Ile 
            20                  25                  30          


Pro Thr Thr Phe Glu Asn Gly Arg Cys Ile Gln Ala Asn Tyr Ser Leu 
        35                  40                  45              


Met Glu Asn Gly Lys Ile Lys Val Leu Asn Gln Glu Leu Arg Ala Asp 
    50                  55                  60                  


Gly Thr Val Asn Gln Ile Glu Gly Glu Ala Thr Pro Val Asn Leu Thr 
65                  70                  75                  80  


Glu Pro Ala Lys Leu Glu Val Lys Phe Ser Trp Phe Met Pro Ser Ala 
                85                  90                  95      


Pro Tyr Trp Ile Leu Ala Thr Asp Tyr Glu Asn Tyr Ala Leu Val Tyr 
            100                 105                 110         


Ser Cys Thr Cys Ile Ile Gln Leu Phe His Val Asp Phe Ala Trp Ile 
        115                 120                 125             


Leu Ala Arg Asn Pro Asn Leu Pro Pro Glu Thr Val Asp Ser Leu Lys 
    130                 135                 140                 


Asn Ile Leu Thr Ser Asn Asn Ile Asp Val Lys Lys Met Thr Val Thr 
145                 150                 155                 160 


Asp Gln Val Asn Cys Pro Lys Leu Ser 
                165                 


<210>  1982
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  1982

Met Leu Thr Glu Leu Glu Lys Ala Leu Asn Ser Ile Ile Asp Val Tyr 
1               5                   10                  15      


His Lys Tyr Ser Leu Ile Lys Gly Asn Phe His Ala Val Tyr Arg Asp 
            20                  25                  30          


Asp Leu Lys Lys Leu Leu Glu Thr Glu Cys Pro Gln Tyr Ile Arg Lys 
        35                  40                  45              


Lys Gly Ala Asp Val Trp Phe Lys Glu Leu Asp Ile Asn Thr Asp Gly 
    50                  55                  60                  


Ala Val Asn Phe Gln Glu Phe Leu Ile Leu Val Ile Lys Met Gly Val 
65                  70                  75                  80  


Ala Ala His Lys Lys Ser His Glu Glu Ser His Lys Glu 
                85                  90              


<210>  1983
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  1983

Ser Thr Pro Leu Met Ser Trp Pro Trp Ser Pro Ser Ala Leu Arg Leu 
1               5                   10                  15      


Leu Gln Arg Pro Pro Glu Glu Pro Ala Ala His Ala Asn Cys His Arg 
            20                  25                  30          


Val Ala Leu Asn Ile Ser Phe Gln Glu Leu Gly Trp Glu Arg Trp Ile 
        35                  40                  45              


Val Tyr Pro Pro Ser Phe Ile Phe His Tyr Cys His Gly Gly Cys Gly 
    50                  55                  60                  


Leu His Ile Pro Pro Asn Leu Ser Leu Pro Val Pro Gly Ala Pro Pro 
65                  70                  75                  80  


Thr Pro Ala Gln Pro Tyr Ser Leu Leu Pro Gly Ala Gln Pro Cys Cys 
                85                  90                  95      


Ala Ala Leu Pro Gly Thr Met Arg Pro Leu His Val Arg Thr Thr Ser 
            100                 105                 110         


Asp Gly Gly Tyr Ser Phe Lys Tyr Glu Thr Val Pro Asn Leu Leu Thr 
        115                 120                 125             


Gln His Cys Ala Cys Ile 
    130                 


<210>  1984
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  1984

Met Glu Asp Leu Cys Val Ala Asn Thr Leu Phe Ala Leu Asn Leu Phe 
1               5                   10                  15      


Lys His Leu Ala Lys Ala Ser Pro Thr Gln Asn Leu Phe Leu Ser Pro 
            20                  25                  30          


Trp Ser Ile Ser Ser Thr Met Ala Met Val Tyr Met Gly Ser Arg Gly 
        35                  40                  45              


Ser Thr Glu Asp Gln Met Ala Lys Val Leu Gln Phe Asn Glu Val Gly 
    50                  55                  60                  


Ala Asn Ala Val Thr Pro Met Thr Pro Glu Asn Phe Thr Ser Cys Gly 
65                  70                  75                  80  


Phe Met Gln Gln Ile Gln Lys Gly Ser Tyr Pro Asp Ala Ile Leu Gln 
                85                  90                  95      


Ala Gln Ala Ala Asp Lys Ile His Ser Ser Phe Arg Ser Leu Ser Ser 
            100                 105                 110         


Ala Ile Asn Ala Ser Thr Gly Asn Tyr Leu Leu Glu Ser Val Asn Lys 
        115                 120                 125             


Leu Phe Gly Glu Lys Ser Ala Ser Phe Arg Glu Glu Tyr Ile Arg Leu 
    130                 135                 140                 


Cys Gln Lys Tyr Tyr Ser Ser Glu Pro Gln Ala Val Asp Phe Leu Glu 
145                 150                 155                 160 


Cys Ala Glu Glu Ala Arg Lys Lys Ile Tyr Ser Trp Val Lys Thr Gln 
                165                 170                 175     


Thr Lys Gly Lys Ile Pro Asn Leu Leu Pro Glu Gly Ser Val Asp Gly 
            180                 185                 190         


Asp Thr Arg Met Val Leu Val Asn Ala Val Tyr Phe Lys Gly Lys Trp 
        195                 200                 205             


Lys Thr Pro Phe Glu Lys Lys Leu Asn Gly Leu Tyr Pro Phe Arg Val 
    210                 215                 220                 


Asn Ser Ala Gln Arg Thr Pro Val Gln Met Met Tyr Leu Arg Glu Lys 
225                 230                 235                 240 


Leu Asn Ile Gly Tyr Ile Glu Asp Leu Lys Ala Gln Ile Leu Glu Leu 
                245                 250                 255     


Pro Tyr Ala Gly Asp Val Ser Met Phe Leu Leu Leu Pro Asp Glu Ile 
            260                 265                 270         


Ala Asp Val Ser Thr Gly Leu Glu Leu Leu Glu Ser Glu Ile Thr Tyr 
        275                 280                 285             


Asp Lys Leu Asn Lys Trp Thr Ser Lys Asp Lys Met Ala Glu Asp Glu 
    290                 295                 300                 


Val Glu Val Tyr Ile Pro Gln Phe Lys Leu Glu Glu His Tyr Glu Leu 
305                 310                 315                 320 


Arg Ser Ile Leu Arg Ser Met Gly Met Glu Asp Ala Phe Asn Lys Gly 
                325                 330                 335     


Arg Ala Asn Phe Ser Gly Met Ser Glu Arg Asn Asp Leu Phe Leu Ser 
            340                 345                 350         


Glu Val Phe His Gln Ala Met Val Asp Val Asn Glu Glu Gly Thr Glu 
        355                 360                 365             


Ala Ala Ala Gly Thr Gly Gly Val Met Thr Gly Arg Thr Gly His Gly 
    370                 375                 380                 


Gly Pro Gln Phe Val Ala Asp His Pro Phe Leu Phe Leu Ile Met His 
385                 390                 395                 400 


Lys Ile Thr Asn Cys Ile Leu Phe Phe Gly Arg Phe Ser Ser Pro 
                405                 410                 415 


<210>  1985
<211>  379
<212>  PRT
<213>  Homo Sapiens

<400>  1985

Val His His Pro Pro Ser Tyr Val Ala His Leu Ala Ser Asp Phe Gly 
1               5                   10                  15      


Val Arg Val Phe Gln Gln Val Ala Gln Ala Ser Lys Asp Arg Asn Val 
            20                  25                  30          


Val Phe Ser Pro Tyr Gly Val Ala Ser Val Leu Ala Met Leu Gln Leu 
        35                  40                  45              


Thr Thr Gly Gly Glu Thr Gln Gln Gln Ile Gln Ala Ala Met Gly Phe 
    50                  55                  60                  


Lys Ile Asp Asp Lys Gly Met Ala Pro Ala Leu Arg His Leu Tyr Lys 
65                  70                  75                  80  


Glu Leu Met Gly Pro Trp Asn Lys Asp Glu Ile Ser Thr Thr Asp Ala 
                85                  90                  95      


Ile Phe Val Gln Arg Asp Leu Lys Leu Val Gln Gly Phe Met Pro His 
            100                 105                 110         


Phe Phe Arg Leu Phe Arg Ser Thr Val Lys Gln Val Asp Phe Ser Glu 
        115                 120                 125             


Val Glu Arg Ala Arg Phe Ile Ile Asn Asp Trp Val Lys Thr His Thr 
    130                 135                 140                 


Lys Gly Met Ile Ser Asn Leu Leu Gly Lys Gly Ala Val Asp Gln Leu 
145                 150                 155                 160 


Thr Arg Leu Val Leu Val Asn Ala Leu Tyr Phe Asn Gly Gln Trp Lys 
                165                 170                 175     


Thr Pro Phe Pro Asp Ser Ser Thr His Arg Arg Leu Phe His Lys Ser 
            180                 185                 190         


Asp Gly Ser Thr Val Ser Val Pro Met Met Ala Gln Thr Asn Lys Phe 
        195                 200                 205             


Asn Tyr Thr Glu Phe Thr Thr Pro Asp Gly His Tyr Tyr Asp Ile Leu 
    210                 215                 220                 


Glu Leu Pro Tyr His Gly Asp Thr Leu Ser Met Phe Ile Ala Ala Pro 
225                 230                 235                 240 


Tyr Glu Lys Glu Val Pro Leu Ser Ala Leu Thr Asn Ile Leu Ser Ala 
                245                 250                 255     


Gln Leu Ile Ser His Trp Lys Gly Asn Met Thr Arg Leu Pro Arg Leu 
            260                 265                 270         


Leu Val Leu Pro Lys Phe Ser Leu Glu Thr Glu Val Asp Leu Arg Lys 
        275                 280                 285             


Pro Leu Glu Asn Leu Gly Met Thr Asp Met Phe Arg Gln Phe Gln Ala 
    290                 295                 300                 


Asp Phe Thr Ser Leu Ser Asp Gln Glu Pro Leu His Val Ala Gln Ala 
305                 310                 315                 320 


Leu Gln Lys Val Lys Ile Glu Val Asn Glu Ser Gly Thr Val Ala Ser 
                325                 330                 335     


Ser Ser Thr Ala Val Ile Val Ser Ala Arg Met Ala Pro Glu Glu Ile 
            340                 345                 350         


Ile Met Asp Arg Pro Phe Leu Phe Val Val Arg His Asn Pro Thr Gly 
        355                 360                 365             


Thr Val Leu Phe Met Gly Gln Val Met Glu Pro 
    370                 375                 


<210>  1986
<211>  381
<212>  PRT
<213>  Homo Sapiens

<400>  1986

Glu Met Lys Lys Arg Val Glu Asp Leu His Val Gly Ala Thr Val Ala 
1               5                   10                  15      


Pro Ser Ser Arg Arg Asp Phe Thr Phe Asp Leu Tyr Arg Ala Leu Ala 
            20                  25                  30          


Ser Ala Ala Pro Ser Gln Asn Ile Phe Phe Ser Pro Val Ser Ile Ser 
        35                  40                  45              


Met Ser Leu Ala Met Leu Ser Leu Gly Ala Gly Ser Ser Thr Lys Met 
    50                  55                  60                  


Gln Ile Leu Glu Gly Leu Gly Leu Asn Leu Gln Lys Ser Ser Glu Lys 
65                  70                  75                  80  


Glu Leu His Arg Gly Phe Gln Gln Leu Leu Gln Glu Leu Asn Gln Pro 
                85                  90                  95      


Arg Asp Gly Phe Gln Leu Ser Leu Gly Asn Ala Leu Phe Thr Asp Leu 
            100                 105                 110         


Val Val Asp Leu Gln Asp Thr Phe Val Ser Ala Met Lys Thr Leu Tyr 
        115                 120                 125             


Leu Ala Asp Thr Phe Pro Thr Asn Phe Arg Asp Ser Ala Gly Ala Met 
    130                 135                 140                 


Lys Gln Ile Asn Asp Tyr Val Ala Lys Gln Thr Lys Gly Lys Ile Val 
145                 150                 155                 160 


Asp Leu Leu Lys Asn Leu Asp Ser Asn Ala Val Val Ile Met Val Asn 
                165                 170                 175     


Tyr Ile Phe Phe Lys Ala Lys Trp Glu Thr Ser Phe Asn His Lys Gly 
            180                 185                 190         


Thr Gln Glu Gln Asp Phe Tyr Val Thr Ser Glu Thr Val Val Arg Val 
        195                 200                 205             


Pro Met Met Ser Arg Glu Asp Gln Tyr His Tyr Leu Leu Asp Arg Asn 
    210                 215                 220                 


Leu Ser Cys Arg Val Val Gly Val Pro Tyr Gln Gly Asn Ala Thr Ala 
225                 230                 235                 240 


Leu Phe Ile Leu Pro Ser Glu Gly Lys Met Gln Gln Val Glu Asn Gly 
                245                 250                 255     


Leu Ser Glu Lys Thr Leu Arg Lys Trp Leu Lys Met Phe Lys Lys Arg 
            260                 265                 270         


Gln Leu Glu Leu Tyr Leu Pro Lys Phe Ser Ile Glu Gly Ser Tyr Gln 
        275                 280                 285             


Leu Glu Lys Val Leu Pro Ser Leu Gly Ile Ser Asn Val Phe Thr Ser 
    290                 295                 300                 


His Ala Asp Leu Ser Gly Ile Ser Asn His Ser Asn Ile Gln Val Ser 
305                 310                 315                 320 


Glu Met Val His Lys Ala Val Val Glu Val Asp Glu Ser Gly Thr Arg 
                325                 330                 335     


Ala Ala Ala Ala Thr Gly Thr Ile Phe Thr Phe Arg Ser Ala Arg Leu 
            340                 345                 350         


Asn Ser Gln Arg Leu Val Phe Asn Arg Pro Phe Leu Met Phe Ile Val 
        355                 360                 365             


Asp Asn Asn Ile Leu Phe Leu Gly Lys Val Asn Arg Pro 
    370                 375                 380     


<210>  1987
<211>  478
<212>  PRT
<213>  Homo Sapiens

<400>  1987

Asn Pro Asn Ala Thr Ser Ser Ser Ser Gln Asp Pro Glu Ser Leu Gln 
1               5                   10                  15      


Asp Arg Gly Glu Gly Lys Val Ala Thr Thr Val Ile Ser Lys Met Leu 
            20                  25                  30          


Phe Val Glu Pro Ile Leu Glu Val Ser Ser Leu Pro Thr Thr Asn Ser 
        35                  40                  45              


Thr Thr Asn Ser Ala Thr Lys Ile Thr Ala Asn Thr Thr Asp Glu Pro 
    50                  55                  60                  


Thr Thr Gln Pro Thr Thr Glu Pro Thr Thr Gln Pro Thr Ile Gln Pro 
65                  70                  75                  80  


Thr Gln Pro Thr Thr Gln Leu Pro Thr Asp Ser Pro Thr Gln Pro Thr 
                85                  90                  95      


Thr Gly Ser Phe Cys Pro Gly Pro Val Thr Leu Cys Ser Asp Leu Glu 
            100                 105                 110         


Ser His Ser Thr Glu Ala Val Leu Gly Asp Ala Leu Val Asp Phe Ser 
        115                 120                 125             


Leu Lys Leu Tyr His Ala Phe Ser Ala Met Lys Lys Val Glu Thr Asn 
    130                 135                 140                 


Met Ala Phe Ser Pro Phe Ser Ile Ala Ser Leu Leu Thr Gln Val Leu 
145                 150                 155                 160 


Leu Gly Ala Gly Glu Asn Thr Lys Thr Asn Leu Glu Ser Ile Leu Ser 
                165                 170                 175     


Tyr Pro Lys Asp Phe Thr Cys Val His Gln Ala Leu Lys Gly Phe Thr 
            180                 185                 190         


Thr Lys Gly Val Thr Ser Val Ser Gln Ile Phe His Ser Pro Asp Leu 
        195                 200                 205             


Ala Ile Arg Asp Thr Phe Val Asn Ala Ser Arg Thr Leu Tyr Ser Ser 
    210                 215                 220                 


Ser Pro Arg Val Leu Ser Asn Asn Ser Asp Ala Asn Leu Glu Leu Ile 
225                 230                 235                 240 


Asn Thr Trp Val Ala Lys Asn Thr Asn Asn Lys Ile Ser Arg Leu Leu 
                245                 250                 255     


Asp Ser Leu Pro Ser Asp Thr Arg Leu Val Leu Leu Asn Ala Ile Tyr 
            260                 265                 270         


Leu Ser Ala Lys Trp Lys Thr Thr Phe Asp Pro Lys Lys Thr Arg Met 
        275                 280                 285             


Glu Pro Phe His Phe Lys Asn Ser Val Ile Lys Val Pro Met Met Asn 
    290                 295                 300                 


Ser Lys Lys Tyr Pro Val Ala His Phe Ile Asp Gln Thr Leu Lys Ala 
305                 310                 315                 320 


Lys Val Gly Gln Leu Gln Leu Ser His Asn Leu Ser Leu Val Ile Leu 
                325                 330                 335     


Val Pro Gln Asn Leu Lys His Arg Leu Glu Asp Met Glu Gln Ala Leu 
            340                 345                 350         


Ser Pro Ser Val Phe Lys Ala Ile Met Glu Lys Leu Glu Met Ser Lys 
        355                 360                 365             


Phe Gln Pro Thr Leu Leu Thr Leu Pro Arg Ile Lys Val Thr Thr Ser 
    370                 375                 380                 


Gln Asp Met Leu Ser Ile Met Glu Lys Leu Glu Phe Phe Asp Phe Ser 
385                 390                 395                 400 


Tyr Asp Leu Asn Leu Cys Gly Leu Thr Glu Asp Pro Asp Leu Gln Val 
                405                 410                 415     


Ser Ala Met Gln His Gln Thr Val Leu Glu Leu Thr Glu Thr Gly Val 
            420                 425                 430         


Glu Ala Ala Ala Ala Ser Ala Ile Ser Val Ala Arg Thr Leu Leu Val 
        435                 440                 445             


Phe Glu Val Gln Gln Pro Phe Leu Phe Met Leu Trp Asp Gln Gln His 
    450                 455                 460                 


Lys Phe Pro Val Phe Met Gly Arg Val Tyr Asp Pro Arg Ala 
465                 470                 475             


<210>  1988
<211>  641
<212>  PRT
<213>  Homo Sapiens

<400>  1988

Glu Glu Lys Pro Cys Gly Phe Pro His Val Glu Asn Gly Arg Ile Ala 
1               5                   10                  15      


Gln Tyr Tyr Tyr Thr Phe Lys Ser Phe Tyr Phe Pro Met Ser Ile Asp 
            20                  25                  30          


Lys Lys Leu Ser Phe Phe Cys Leu Ala Gly Tyr Thr Thr Glu Ser Gly 
        35                  40                  45              


Arg Gln Glu Glu Gln Thr Thr Cys Thr Thr Glu Gly Trp Ser Pro Glu 
    50                  55                  60                  


Pro Arg Cys Phe Lys Lys Cys Thr Lys Pro Asp Leu Ser Asn Gly Tyr 
65                  70                  75                  80  


Ile Ser Asp Val Lys Leu Leu Tyr Lys Ile Gln Glu Asn Met Arg Tyr 
                85                  90                  95      


Gly Cys Ala Ser Gly Tyr Lys Thr Thr Gly Gly Lys Asp Glu Glu Val 
            100                 105                 110         


Val Gln Cys Leu Ser Asp Gly Trp Ser Ser Gln Pro Thr Cys Arg Lys 
        115                 120                 125             


Glu His Glu Thr Cys Leu Ala Pro Glu Leu Tyr Asn Gly Asn Tyr Ser 
    130                 135                 140                 


Thr Thr Gln Lys Thr Phe Lys Val Lys Asp Lys Val Gln Tyr Glu Cys 
145                 150                 155                 160 


Ala Thr Gly Tyr Tyr Thr Ala Gly Gly Lys Lys Thr Glu Glu Val Glu 
                165                 170                 175     


Cys Leu Thr Tyr Gly Trp Ser Leu Thr Pro Lys Cys Thr Lys Leu Lys 
            180                 185                 190         


Cys Ser Ser Leu Arg Leu Ile Glu Asn Gly Tyr Phe His Pro Val Lys 
        195                 200                 205             


Gln Thr Tyr Glu Glu Gly Asp Val Val Gln Phe Phe Cys His Glu Asn 
    210                 215                 220                 


Tyr Tyr Leu Ser Gly Ser Asp Leu Ile Gln Cys Tyr Asn Phe Gly Trp 
225                 230                 235                 240 


Tyr Pro Glu Ser Pro Val Cys Glu Gly Arg Arg Asn Arg Cys Pro Pro 
                245                 250                 255     


Pro Pro Leu Pro Ile Asn Ser Lys Ile Gln Thr His Ser Thr Thr Tyr 
            260                 265                 270         


Arg His Gly Glu Ile Val His Ile Glu Cys Glu Leu Asn Phe Glu Ile 
        275                 280                 285             


His Gly Ser Ala Glu Ile Arg Cys Glu Asp Gly Lys Trp Thr Glu Pro 
    290                 295                 300                 


Pro Lys Cys Ile Glu Gly Gln Glu Lys Val Ala Cys Glu Glu Pro Pro 
305                 310                 315                 320 


Phe Ile Glu Asn Gly Ala Ala Asn Leu His Ser Lys Ile Tyr Tyr Asn 
                325                 330                 335     


Gly Asp Lys Val Thr Tyr Ala Cys Lys Ser Gly Tyr Leu Leu His Gly 
            340                 345                 350         


Ser Asn Glu Ile Thr Cys Asn Arg Gly Lys Trp Thr Leu Pro Pro Glu 
        355                 360                 365             


Cys Val Glu Asn Asn Glu Asn Cys Lys His Pro Pro Val Val Met Asn 
    370                 375                 380                 


Gly Ala Val Ala Asp Gly Ile Leu Ala Ser Tyr Ala Thr Gly Ser Ser 
385                 390                 395                 400 


Val Glu Tyr Arg Cys Asn Glu Tyr Tyr Leu Leu Arg Gly Ser Lys Ile 
                405                 410                 415     


Ser Arg Cys Glu Gln Gly Lys Trp Ser Ser Pro Pro Val Cys Leu Glu 
            420                 425                 430         


Pro Cys Thr Val Asn Val Asp Tyr Met Asn Arg Asn Asn Ile Glu Met 
        435                 440                 445             


Lys Trp Lys Tyr Glu Gly Lys Val Leu His Gly Asp Leu Ile Asp Phe 
    450                 455                 460                 


Val Cys Lys Gln Gly Tyr Asp Leu Ser Pro Leu Thr Pro Leu Ser Glu 
465                 470                 475                 480 


Leu Ser Val Gln Cys Asn Arg Gly Glu Val Lys Tyr Pro Leu Cys Thr 
                485                 490                 495     


Arg Lys Glu Ser Lys Gly Met Cys Thr Ser Pro Pro Leu Ile Lys His 
            500                 505                 510         


Gly Val Ile Ile Ser Ser Thr Val Asp Thr Tyr Glu Asn Gly Ser Ser 
        515                 520                 525             


Val Glu Tyr Arg Cys Phe Asp His His Phe Leu Glu Gly Ser Arg Glu 
    530                 535                 540                 


Ala Tyr Cys Leu Asp Gly Met Trp Thr Thr Pro Pro Leu Cys Leu Glu 
545                 550                 555                 560 


Pro Cys Thr Leu Ser Phe Thr Glu Met Glu Lys Asn Asn Leu Leu Leu 
                565                 570                 575     


Lys Trp Asp Phe Asp Asn Arg Pro His Ile Leu His Gly Glu Tyr Ile 
            580                 585                 590         


Glu Phe Ile Cys Arg Gly Asp Thr Tyr Pro Ala Glu Leu Tyr Ile Thr 
        595                 600                 605             


Gly Ser Ile Leu Arg Met Gln Cys Asp Arg Gly Gln Leu Lys Tyr Pro 
    610                 615                 620                 


Arg Cys Ile Pro Arg Gln Ser Thr Leu Ser Tyr Gln Glu Pro Leu Arg 
625                 630                 635                 640 


Thr 
    


<210>  1989
<211>  581
<212>  PRT
<213>  Homo Sapiens

<400>  1989

Val Thr Cys Pro Glu Gln Asp Lys Tyr Arg Thr Ile Thr Gly Met Cys 
1               5                   10                  15      


Asn Asn Arg Arg Ser Pro Thr Leu Gly Ala Ser Asn Arg Ala Phe Val 
            20                  25                  30          


Arg Trp Leu Pro Ala Glu Tyr Glu Asp Gly Phe Ser Leu Pro Tyr Gly 
        35                  40                  45              


Trp Thr Pro Gly Val Lys Arg Asn Gly Phe Pro Val Ala Leu Ala Arg 
    50                  55                  60                  


Ala Val Ser Asn Glu Ile Val Arg Phe Pro Thr Asp Gln Leu Thr Pro 
65                  70                  75                  80  


Asp Gln Glu Arg Ser Leu Met Phe Met Gln Trp Gly Gln Leu Leu Asp 
                85                  90                  95      


His Asp Leu Asp Phe Thr Pro Glu Pro Ala Ala Arg Ala Ser Phe Val 
            100                 105                 110         


Thr Gly Val Asn Cys Glu Thr Ser Cys Val Gln Gln Pro Pro Cys Phe 
        115                 120                 125             


Pro Leu Lys Ile Pro Pro Asn Asp Pro Arg Ile Lys Asn Gln Ala Asp 
    130                 135                 140                 


Cys Ile Pro Phe Phe Arg Ser Cys Pro Ala Cys Pro Gly Ser Asn Ile 
145                 150                 155                 160 


Thr Ile Arg Asn Gln Ile Asn Ala Leu Thr Ser Phe Val Asp Ala Ser 
                165                 170                 175     


Met Val Tyr Gly Ser Glu Glu Pro Leu Ala Arg Asn Leu Arg Asn Met 
            180                 185                 190         


Ser Asn Gln Leu Gly Leu Leu Ala Val Asn Gln Arg Phe Gln Asp Asn 
        195                 200                 205             


Gly Arg Ala Leu Leu Pro Phe Asp Asn Leu His Asp Asp Pro Cys Leu 
    210                 215                 220                 


Leu Thr Asn Arg Ser Ala Arg Ile Pro Cys Phe Leu Ala Gly Asp Thr 
225                 230                 235                 240 


Arg Ser Ser Glu Met Pro Glu Leu Thr Ser Met His Thr Leu Leu Leu 
                245                 250                 255     


Arg Glu His Asn Arg Leu Ala Thr Glu Leu Lys Ser Leu Asn Pro Arg 
            260                 265                 270         


Trp Asp Gly Glu Arg Leu Tyr Gln Glu Ala Arg Lys Ile Val Gly Ala 
        275                 280                 285             


Met Val Gln Ile Ile Thr Tyr Arg Asp Tyr Leu Pro Leu Val Leu Gly 
    290                 295                 300                 


Pro Thr Ala Met Arg Lys Tyr Leu Pro Thr Tyr Arg Ser Tyr Asn Asp 
305                 310                 315                 320 


Ser Val Asp Pro Arg Ile Ala Asn Val Phe Thr Asn Ala Phe Arg Tyr 
                325                 330                 335     


Gly His Thr Leu Ile Gln Pro Phe Met Phe Arg Leu Asp Asn Arg Tyr 
            340                 345                 350         


Gln Pro Met Glu Pro Asn Pro Arg Val Pro Leu Ser Arg Val Phe Phe 
        355                 360                 365             


Ala Ser Trp Arg Val Val Leu Glu Gly Gly Ile Asp Pro Ile Leu Arg 
    370                 375                 380                 


Gly Leu Met Ala Thr Pro Ala Lys Leu Asn Arg Gln Asn Gln Ile Ala 
385                 390                 395                 400 


Val Asp Glu Ile Arg Glu Arg Leu Phe Glu Gln Val Met Arg Ile Gly 
                405                 410                 415     


Leu Asp Leu Pro Ala Leu Asn Met Gln Arg Ser Arg Asp His Gly Leu 
            420                 425                 430         


Pro Gly Tyr Asn Ala Trp Arg Arg Phe Cys Gly Leu Pro Gln Pro Glu 
        435                 440                 445             


Thr Val Gly Gln Leu Gly Thr Val Leu Arg Asn Leu Lys Leu Ala Arg 
    450                 455                 460                 


Lys Leu Met Glu Gln Tyr Gly Thr Pro Asn Asn Ile Asp Ile Trp Met 
465                 470                 475                 480 


Gly Gly Val Ser Glu Pro Leu Lys Arg Lys Gly Arg Val Gly Pro Leu 
                485                 490                 495     


Leu Ala Cys Ile Ile Gly Thr Gln Phe Arg Lys Leu Arg Asp Gly Asp 
            500                 505                 510         


Arg Phe Trp Trp Glu Asn Glu Gly Val Phe Ser Met Gln Gln Arg Gln 
        515                 520                 525             


Ala Leu Ala Gln Ile Ser Leu Pro Arg Ile Ile Cys Asp Asn Thr Gly 
    530                 535                 540                 


Ile Thr Thr Val Ser Lys Asn Asn Ile Phe Met Ser Asn Ser Tyr Pro 
545                 550                 555                 560 


Arg Asp Phe Val Asn Cys Ser Thr Leu Pro Ala Leu Asn Leu Ala Ser 
                565                 570                 575     


Trp Arg Glu Ala Ser 
            580     


<210>  1990
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  1990

Leu Val Pro Glu Lys Glu Lys Asp Pro Lys Tyr Trp Arg Asp Gln Ala 
1               5                   10                  15      


Gln Glu Thr Leu Lys Tyr Ala Leu Glu Leu Gln Lys Leu Asn Thr Asn 
            20                  25                  30          


Val Ala Lys Asn Val Ile Met Phe Leu Gly Asp Gly Met Gly Val Ser 
        35                  40                  45              


Thr Val Thr Ala Ala Arg Ile Leu Lys Gly Gln Leu His His Asn Pro 
    50                  55                  60                  


Gly Glu Glu Thr Arg Leu Glu Met Asp Lys Phe Pro Phe Val Ala Leu 
65                  70                  75                  80  


Ser Lys Thr Tyr Asn Thr Asn Ala Gln Val Pro Asp Ser Ala Gly Thr 
                85                  90                  95      


Ala Thr Ala Tyr Leu Cys Gly Val Lys Ala Asn Glu Gly Thr Val Gly 
            100                 105                 110         


Val Ser Ala Ala Thr Glu Arg Ser Arg Cys Asn Thr Thr Gln Gly Asn 
        115                 120                 125             


Glu Val Thr Ser Ile Leu Arg Trp Ala Lys Asp Ala Gly Lys Ser Val 
    130                 135                 140                 


Gly Ile Val Thr Thr Thr Arg Val Asn His Ala Thr Pro Ser Ala Ala 
145                 150                 155                 160 


Tyr Ala His Ser Ala Asp Arg Asp Trp Tyr Ser Asp Asn Glu Met Pro 
                165                 170                 175     


Pro Glu Ala Leu Ser Gln Gly Cys Lys Asp Ile Ala Tyr Gln Leu Met 
            180                 185                 190         


His Asn Ile Arg Asp Ile Asp Val Ile Met Gly Gly Gly Arg Lys Tyr 
        195                 200                 205             


Met Tyr Pro Lys Asn Lys Thr Asp Val Glu Tyr Glu Ser Asp Glu Lys 
    210                 215                 220                 


Ala Arg Gly Thr Arg Leu Asp Gly Leu Asp Leu Val Asp Thr Trp Lys 
225                 230                 235                 240 


Ser Phe Lys Pro Arg His Lys His Ser His Phe Ile Trp Asn Arg Thr 
                245                 250                 255     


Glu Leu Leu Thr Leu Asp Pro His Asn Val Asp Tyr Leu Leu Gly Leu 
            260                 265                 270         


Phe Glu Pro Gly Asp Met Gln Tyr Glu Leu Asn Arg Asn Asn Val Thr 
        275                 280                 285             


Asp Pro Ser Leu Ser Glu Met Val Val Val Ala Ile Gln Ile Leu Arg 
    290                 295                 300                 


Lys Asn Pro Lys Gly Phe Phe Leu Leu Val Glu Gly Gly Arg Ile Asp 
305                 310                 315                 320 


His Gly His His Glu Gly Lys Ala Lys Gln Ala Leu His Glu Ala Val 
                325                 330                 335     


Glu Met Asp Arg Ala Ile Gly Gln Ala Gly Ser Leu Thr Ser Ser Glu 
            340                 345                 350         


Asp Thr Leu Thr Val Val Thr Ala Asp His Ser His Val Phe Thr Phe 
        355                 360                 365             


Gly Gly Tyr Thr Pro Arg Gly Asn Ser Ile Phe Gly Leu Ala Pro Met 
    370                 375                 380                 


Leu Ser Asp Thr Asp Lys Lys Pro Phe Thr Ala Ile Leu Tyr Gly Asn 
385                 390                 395                 400 


Gly Pro Gly Tyr Lys Val Val Gly Gly Glu Arg Glu Asn Val Ser Met 
                405                 410                 415     


Val Asp Tyr Ala His Asn Asn Tyr Gln Ala Gln Ser Ala Val Pro Leu 
            420                 425                 430         


Arg His Glu Thr His Gly Gly Glu Asp Val Ala Val Phe Ser Lys Gly 
        435                 440                 445             


Pro Met Ala His Leu Leu His Gly Val His Glu Gln Asn Tyr Val Pro 
    450                 455                 460                 


His Val Met Ala Tyr Ala Ala Cys Ile Gly Ala Asn Leu Gly His Cys 
465                 470                 475                 480 


Ala Pro Ala Ser 
                


<210>  1991
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  1991

Ile Ile Pro Val Glu Glu Glu Asn Pro Asp Phe Trp Asn Arg Gln Ala 
1               5                   10                  15      


Ala Glu Ala Leu Gly Ala Ala Lys Lys Leu Gln Pro Ala Gln Thr Ala 
            20                  25                  30          


Ala Lys Asn Leu Ile Ile Phe Leu Gly Asp Gly Met Gly Val Ser Thr 
        35                  40                  45              


Val Thr Ala Ala Arg Ile Leu Lys Gly Gln Lys Lys Asp Lys Leu Gly 
    50                  55                  60                  


Pro Glu Thr Phe Leu Ala Met Asp Arg Phe Pro Tyr Val Ala Leu Ser 
65                  70                  75                  80  


Lys Thr Tyr Ser Val Asp Lys His Val Pro Asp Ser Gly Ala Thr Ala 
                85                  90                  95      


Thr Ala Tyr Leu Cys Gly Val Lys Gly Asn Phe Gln Thr Ile Gly Leu 
            100                 105                 110         


Ser Ala Ala Ala Arg Phe Asn Gln Cys Asn Thr Thr Arg Gly Asn Glu 
        115                 120                 125             


Val Ile Ser Val Met Asn Arg Ala Lys Lys Ala Gly Lys Ser Val Gly 
    130                 135                 140                 


Val Val Thr Thr Thr Arg Val Gln His Ala Ser Pro Ala Gly Ala Tyr 
145                 150                 155                 160 


Ala His Thr Val Asn Arg Asn Trp Tyr Ser Asp Ala Asp Val Pro Ala 
                165                 170                 175     


Ser Ala Arg Gln Glu Gly Cys Gln Asp Ile Ala Thr Gln Leu Ile Ser 
            180                 185                 190         


Asn Met Asp Ile Asp Val Ile Leu Gly Gly Gly Arg Lys Tyr Met Phe 
        195                 200                 205             


Pro Met Gly Thr Pro Asp Pro Glu Tyr Pro Asp Asp Tyr Ser Gln Gly 
    210                 215                 220                 


Gly Thr Arg Leu Asp Gly Lys Asn Leu Val Gln Glu Trp Leu Ala Lys 
225                 230                 235                 240 


Arg Gln Gly Ala Arg Tyr Val Trp Asn Arg Thr Glu Leu Met Gln Ala 
                245                 250                 255     


Ser Leu Asp Pro Ser Val Thr His Leu Met Gly Leu Phe Glu Pro Gly 
            260                 265                 270         


Asp Met Lys Tyr Glu Ile His Arg Asp Ser Thr Leu Asp Pro Ser Leu 
        275                 280                 285             


Met Glu Met Thr Glu Ala Ala Leu Arg Leu Leu Ser Arg Asn Pro Arg 
    290                 295                 300                 


Gly Phe Phe Leu Phe Val Glu Gly Gly Arg Ile Asp His Gly His His 
305                 310                 315                 320 


Glu Ser Arg Ala Tyr Arg Ala Leu Thr Glu Thr Ile Met Phe Asp Asp 
                325                 330                 335     


Ala Ile Glu Arg Ala Gly Gln Leu Thr Ser Glu Glu Asp Thr Leu Ser 
            340                 345                 350         


Leu Val Thr Ala Asp His Ser His Val Phe Ser Phe Gly Gly Tyr Pro 
        355                 360                 365             


Leu Arg Gly Ser Ser Ile Phe Gly Leu Ala Pro Gly Lys Ala Arg Asp 
    370                 375                 380                 


Arg Lys Ala Tyr Thr Val Leu Leu Tyr Gly Asn Gly Pro Gly Tyr Val 
385                 390                 395                 400 


Leu Lys Asp Gly Ala Arg Pro Asp Val Thr Glu Ser Glu Ser Gly Ser 
                405                 410                 415     


Pro Glu Tyr Arg Gln Gln Ser Ala Val Pro Leu Asp Gly Glu Thr His 
            420                 425                 430         


Ala Gly Glu Asp Val Ala Val Phe Ala Arg Gly Pro Gln Ala His Leu 
        435                 440                 445             


Val His Gly Val Gln Glu Gln Thr Phe Ile Ala His Val Met Ala Phe 
    450                 455                 460                 


Ala Ala Cys Leu Glu Pro Tyr Thr Ala Cys Asp Leu Ala Pro Arg Ala 
465                 470                 475                 480 


Gly Thr Thr Asp 
                


<210>  1992
<211>  185
<212>  PRT
<213>  Homo Sapiens

<400>  1992

Tyr Ser Pro Arg Thr Pro Asp Arg Val Ser Glu Ala Asp Ile Gln Arg 
1               5                   10                  15      


Leu Leu His Gly Val Met Glu Gln Leu Gly Ile Ala Arg Pro Arg Val 
            20                  25                  30          


Glu Tyr Pro Ala His Gln Ala Met Asn Leu Val Gly Pro Gln Ser Ile 
        35                  40                  45              


Glu Gly Gly Ala His Glu Gly Leu Gln His Leu Gly Pro Phe Gly Asn 
    50                  55                  60                  


Ile Pro Asn Ile Val Ala Glu Leu Thr Gly Asp Asn Ile Pro Lys Asp 
65                  70                  75                  80  


Phe Ser Glu Asp Gln Gly Tyr Pro Asp Pro Pro Asn Pro Cys Pro Val 
                85                  90                  95      


Gly Lys Thr Asp Asp Gly Cys Leu Glu Asn Thr Pro Asp Thr Ala Glu 
            100                 105                 110         


Phe Ser Arg Glu Phe Gln Leu His Gln His Leu Phe Asp Pro Glu His 
        115                 120                 125             


Asp Tyr Pro Gly Leu Gly Lys Trp Asn Lys Lys Leu Leu Tyr Glu Lys 
    130                 135                 140                 


Met Lys Gly Gly Glu Arg Arg Lys Arg Arg Ser Val Asn Pro Tyr Leu 
145                 150                 155                 160 


Gln Gly Gln Arg Leu Asp Asn Val Val Ala Lys Lys Ser Val Pro His 
                165                 170                 175     


Phe Ser Asp Glu Asp Lys Asp Pro Glu 
            180                 185 


<210>  1993
<211>  395
<212>  PRT
<213>  Homo Sapiens

<400>  1993

Ala Ser Pro Glu Gly Lys Val Thr Ala Cys His Ser Ser Gln Pro Asn 
1               5                   10                  15      


Ala Thr Leu Tyr Lys Met Ser Ser Ile Asn Ala Asp Phe Ala Phe Asn 
            20                  25                  30          


Leu Tyr Arg Arg Phe Thr Val Glu Thr Pro Asp Lys Asn Ile Phe Phe 
        35                  40                  45              


Ser Pro Val Ser Ile Ser Ala Ala Leu Val Met Leu Ser Phe Gly Ala 
    50                  55                  60                  


Cys Cys Ser Thr Gln Thr Glu Ile Val Glu Thr Leu Gly Phe Asn Leu 
65                  70                  75                  80  


Thr Asp Thr Pro Met Val Glu Ile Gln His Gly Phe Gln His Leu Ile 
                85                  90                  95      


Cys Ser Leu Asn Phe Pro Lys Lys Glu Leu Glu Leu Gln Ile Gly Asn 
            100                 105                 110         


Ala Leu Phe Ile Gly Lys His Leu Lys Pro Leu Ala Lys Phe Leu Asn 
        115                 120                 125             


Asp Val Lys Thr Leu Tyr Glu Thr Glu Val Phe Ser Thr Asp Phe Ser 
    130                 135                 140                 


Asn Ile Ser Ala Ala Lys Gln Glu Ile Asn Ser His Val Glu Met Gln 
145                 150                 155                 160 


Thr Lys Gly Lys Val Val Gly Leu Ile Gln Asp Leu Lys Pro Asn Thr 
                165                 170                 175     


Ile Met Val Leu Val Asn Tyr Ile His Phe Lys Ala Gln Trp Ala Asn 
            180                 185                 190         


Pro Phe Asp Pro Ser Lys Thr Glu Asp Ser Ser Ser Phe Leu Ile Asp 
        195                 200                 205             


Lys Thr Thr Thr Val Gln Val Pro Met Met His Gln Met Glu Gln Tyr 
    210                 215                 220                 


Tyr His Leu Val Asp Met Glu Leu Asn Cys Thr Val Leu Gln Met Asp 
225                 230                 235                 240 


Tyr Ser Lys Asn Ala Leu Ala Leu Phe Val Leu Pro Lys Glu Gly Gln 
                245                 250                 255     


Met Glu Ser Val Glu Ala Ala Met Ser Ser Lys Thr Leu Lys Lys Trp 
            260                 265                 270         


Asn Arg Leu Leu Gln Lys Gly Trp Val Asp Leu Phe Val Pro Lys Phe 
        275                 280                 285             


Ser Ile Ser Ala Thr Tyr Asp Leu Gly Ala Thr Leu Leu Lys Met Gly 
    290                 295                 300                 


Ile Gln His Ala Tyr Ser Glu Asn Ala Asp Phe Ser Gly Leu Thr Glu 
305                 310                 315                 320 


Asp Asn Gly Leu Lys Leu Ser Asn Ala Ala His Lys Ala Val Leu His 
                325                 330                 335     


Ile Gly Glu Lys Gly Thr Glu Ala Ala Ala Val Pro Glu Val Glu Leu 
            340                 345                 350         


Ser Asp Gln Pro Glu Asn Thr Phe Leu His Pro Ile Ile Gln Ile Asp 
        355                 360                 365             


Arg Ser Phe Met Leu Leu Ile Leu Glu Arg Ser Thr Arg Ser Ile Leu 
    370                 375                 380                 


Phe Leu Gly Lys Val Val Asn Pro Thr Glu Ala 
385                 390                 395 


<210>  1994
<211>  480
<212>  PRT
<213>  Homo Sapiens

<400>  1994

Gly Ser Lys Gly Pro Leu Asp Gln Leu Glu Lys Gly Gly Glu Thr Ala 
1               5                   10                  15      


Gln Ser Ala Asp Pro Gln Trp Glu Gln Leu Asn Asn Lys Asn Leu Ser 
            20                  25                  30          


Met Pro Leu Leu Pro Ala Asp Phe His Lys Glu Asn Thr Val Thr Asn 
        35                  40                  45              


Asp Trp Ile Pro Glu Gly Glu Glu Asp Asp Asp Tyr Leu Asp Leu Glu 
    50                  55                  60                  


Lys Ile Phe Ser Glu Asp Asp Asp Tyr Ile Asp Ile Val Asp Ser Leu 
65                  70                  75                  80  


Ser Val Ser Pro Thr Asp Ser Asp Val Ser Ala Gly Asn Ile Leu Gln 
                85                  90                  95      


Leu Phe His Gly Lys Ser Arg Ile Gln Arg Leu Asn Ile Leu Asn Ala 
            100                 105                 110         


Lys Phe Ala Phe Asn Leu Tyr Arg Val Leu Lys Asp Gln Val Asn Thr 
        115                 120                 125             


Phe Asp Asn Ile Phe Ile Ala Pro Val Gly Ile Ser Thr Ala Met Gly 
    130                 135                 140                 


Met Ile Ser Leu Gly Leu Lys Gly Glu Thr His Glu Gln Val His Ser 
145                 150                 155                 160 


Ile Leu His Phe Lys Asp Phe Val Asn Ala Ser Ser Lys Tyr Glu Ile 
                165                 170                 175     


Thr Thr Ile His Asn Leu Phe Arg Lys Leu Thr His Arg Leu Phe Arg 
            180                 185                 190         


Arg Asn Phe Gly Tyr Thr Leu Arg Ser Val Asn Asp Leu Tyr Ile Gln 
        195                 200                 205             


Lys Gln Phe Pro Ile Leu Leu Asp Phe Lys Thr Lys Val Arg Glu Tyr 
    210                 215                 220                 


Tyr Phe Ala Glu Ala Gln Ile Ala Asp Phe Ser Asp Pro Ala Phe Ile 
225                 230                 235                 240 


Ser Lys Thr Asn Asn His Ile Met Lys Leu Thr Lys Gly Leu Ile Lys 
                245                 250                 255     


Asp Ala Leu Glu Asn Ile Asp Pro Ala Thr Gln Met Met Ile Leu Asn 
            260                 265                 270         


Cys Ile Tyr Phe Lys Gly Ser Trp Val Asn Lys Phe Pro Val Glu Met 
        275                 280                 285             


Thr His Asn His Asn Phe Arg Leu Asn Glu Arg Glu Val Val Lys Val 
    290                 295                 300                 


Ser Met Met Gln Thr Lys Gly Asn Phe Leu Ala Ala Asn Asp Gln Glu 
305                 310                 315                 320 


Leu Asp Cys Asp Ile Leu Gln Leu Glu Tyr Val Gly Gly Ile Ser Met 
                325                 330                 335     


Leu Ile Val Val Pro His Lys Met Ser Gly Met Lys Thr Leu Glu Ala 
            340                 345                 350         


Gln Leu Thr Pro Arg Val Val Glu Arg Trp Gln Lys Ser Met Thr Asn 
        355                 360                 365             


Arg Thr Arg Glu Val Leu Leu Pro Lys Phe Lys Leu Glu Lys Asn Tyr 
    370                 375                 380                 


Asn Leu Val Glu Ser Leu Lys Leu Met Gly Ile Arg Met Leu Phe Asp 
385                 390                 395                 400 


Lys Asn Gly Asn Met Ala Gly Ile Ser Asp Gln Arg Ile Ala Ile Asp 
                405                 410                 415     


Leu Phe Lys His Gln Gly Thr Ile Thr Val Asn Glu Glu Gly Thr Gln 
            420                 425                 430         


Ala Thr Thr Val Thr Thr Val Gly Phe Met Pro Leu Ser Thr Gln Val 
        435                 440                 445             


Arg Phe Thr Val Asp Arg Pro Phe Leu Phe Leu Ile Tyr Glu His Arg 
    450                 455                 460                 


Thr Ser Cys Leu Leu Phe Met Gly Arg Val Ala Asn Pro Ser Arg Ser 
465                 470                 475                 480 


<210>  1995
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  1995

Arg Glu Thr Ile Glu Ser Leu Ser Ser Ser Glu Glu Ser Ile Thr Glu 
1               5                   10                  15      


Tyr Lys Gln Lys Val Glu Lys Val Lys His Glu Asp Gln Gln Gln Gly 
            20                  25                  30          


Glu Asp Glu His Gln Asp Lys Ile Tyr Pro Ser Phe Gln Pro Gln Pro 
        35                  40                  45              


Leu Ile Tyr Pro Phe Val Glu Pro Ile Pro Tyr Gly Phe Leu Pro Gln 
    50                  55                  60                  


Asn Ile Leu Pro Leu Ala Gln Pro Ala Val Val Leu Pro Val Pro Gln 
65                  70                  75                  80  


Pro Glu Ile Met Glu Val Pro Lys Ala Lys Asp Thr Val Tyr Thr Lys 
                85                  90                  95      


Gly Arg Val Met Pro Val Leu Lys Ser Pro Thr Ile Pro Phe Phe Asp 
            100                 105                 110         


Pro Gln Ile Pro Lys Leu Thr Asp Leu Glu Asn Leu His Leu Pro Leu 
        115                 120                 125             


Pro Leu Leu Gln Pro Leu Met Gln Gln Val Pro Gln Pro Ile Pro Gln 
    130                 135                 140                 


Thr Leu Ala Leu Pro Pro Gln Pro Leu Trp Ser Val Pro Gln Pro Lys 
145                 150                 155                 160 


Val Leu Pro Ile Pro Gln Gln Val Val Pro Tyr Pro Gln Arg Ala Val 
                165                 170                 175     


Pro Val Gln Ala Leu Leu Leu Asn Gln Glu Leu Leu Leu Asn Pro Thr 
            180                 185                 190         


His Gln Ile Tyr Pro Val Thr Gln Pro Leu Ala Pro Val His Asn Pro 
        195                 200                 205             


Ile Ser Val 
    210     


<210>  1996
<211>  373
<212>  PRT
<213>  Homo Sapiens

<400>  1996

Arg Ser Asp Gln Glu Pro Leu Tyr Pro Val Gln Val Ser Ser Ala Asp 
1               5                   10                  15      


Ala Arg Leu Met Val Phe Asp Lys Thr Glu Gly Thr Trp Arg Leu Leu 
            20                  25                  30          


Cys Ser Ser Arg Ser Asn Ala Arg Val Ala Gly Leu Ser Cys Glu Glu 
        35                  40                  45              


Met Gly Phe Leu Arg Ala Leu Thr His Ser Glu Leu Asp Val Arg Thr 
    50                  55                  60                  


Ala Gly Ala Asn Gly Thr Ser Gly Phe Phe Cys Val Asp Glu Gly Arg 
65                  70                  75                  80  


Leu Pro His Thr Gln Arg Leu Leu Glu Val Ile Ser Val Cys Asp Cys 
                85                  90                  95      


Pro Arg Gly Arg Phe Leu Ala Ala Ile Cys Gln Asp Cys Gly Arg Arg 
            100                 105                 110         


Lys Leu Pro Val Asp Arg Ile Val Gly Gly Arg Asp Thr Ser Leu Gly 
        115                 120                 125             


Arg Trp Pro Trp Gln Val Ser Leu Arg Tyr Asp Gly Ala His Leu Cys 
    130                 135                 140                 


Gly Gly Ser Leu Leu Ser Gly Asp Trp Val Leu Thr Ala Ala His Cys 
145                 150                 155                 160 


Phe Pro Glu Arg Asn Arg Val Leu Ser Arg Trp Arg Val Phe Ala Gly 
                165                 170                 175     


Ala Val Ala Gln Ala Ser Pro His Gly Leu Gln Leu Gly Val Gln Ala 
            180                 185                 190         


Val Val Tyr His Gly Gly Tyr Leu Pro Phe Arg Asp Pro Asn Ser Glu 
        195                 200                 205             


Glu Asn Ser Asn Asp Ile Ala Leu Val His Leu Ser Ser Pro Leu Pro 
    210                 215                 220                 


Leu Thr Glu Tyr Ile Gln Pro Val Cys Leu Pro Ala Ala Gly Gln Ala 
225                 230                 235                 240 


Leu Val Asp Gly Lys Ile Cys Thr Val Thr Gly Trp Gly Asn Thr Gln 
                245                 250                 255     


Tyr Tyr Gly Gln Gln Ala Gly Val Leu Gln Glu Ala Arg Val Pro Ile 
            260                 265                 270         


Ile Ser Asn Asp Val Cys Asn Gly Ala Asp Phe Tyr Gly Asn Gln Ile 
        275                 280                 285             


Lys Pro Lys Met Phe Cys Ala Gly Tyr Pro Glu Gly Gly Ile Asp Ala 
    290                 295                 300                 


Cys Gln Gly Asp Ser Gly Gly Pro Phe Val Cys Glu Asp Ser Ile Ser 
305                 310                 315                 320 


Arg Thr Pro Arg Trp Arg Leu Cys Gly Ile Val Ser Trp Gly Thr Gly 
                325                 330                 335     


Cys Ala Leu Ala Gln Lys Pro Gly Val Tyr Thr Lys Val Ser Asp Phe 
            340                 345                 350         


Arg Glu Trp Ile Phe Gln Ala Ile Lys Thr His Ser Glu Ala Ser Gly 
        355                 360                 365             


Met Val Thr Gln Leu 
    370             


<210>  1997
<211>  469
<212>  PRT
<213>  Homo Sapiens

<400>  1997

Gly Lys Val Leu Val Trp Pro Thr Glu Phe Ser His Trp Met Asn Ile 
1               5                   10                  15      


Lys Thr Ile Leu Asp Glu Leu Val Gln Arg Gly His Glu Val Thr Val 
            20                  25                  30          


Leu Ala Ser Ser Ala Ser Ile Ser Phe Asp Pro Asn Ser Pro Ser Thr 
        35                  40                  45              


Leu Lys Phe Glu Val Tyr Pro Val Ser Leu Thr Lys Thr Glu Phe Glu 
    50                  55                  60                  


Asp Ile Ile Lys Gln Leu Val Lys Arg Trp Ala Glu Leu Pro Lys Asp 
65                  70                  75                  80  


Thr Phe Trp Ser Tyr Phe Ser Gln Val Gln Glu Ile Met Trp Thr Phe 
                85                  90                  95      


Asn Asp Ile Leu Arg Lys Phe Cys Lys Asp Ile Val Ser Asn Lys Lys 
            100                 105                 110         


Leu Met Lys Lys Leu Gln Glu Ser Arg Phe Asp Val Val Leu Ala Asp 
        115                 120                 125             


Ala Val Phe Pro Phe Gly Glu Leu Leu Ala Glu Leu Leu Lys Ile Pro 
    130                 135                 140                 


Phe Val Tyr Ser Leu Arg Phe Ser Pro Gly Tyr Ala Ile Glu Lys His 
145                 150                 155                 160 


Ser Gly Gly Leu Leu Phe Pro Pro Ser Tyr Val Pro Val Val Met Ser 
                165                 170                 175     


Glu Leu Ser Asp Gln Met Thr Phe Ile Glu Arg Val Lys Asn Met Ile 
            180                 185                 190         


Tyr Val Leu Tyr Phe Glu Phe Trp Phe Gln Ile Phe Asp Met Lys Lys 
        195                 200                 205             


Trp Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu Ser 
    210                 215                 220                 


Glu Thr Met Ala Lys Ala Asp Ile Trp Leu Ile Arg Asn Tyr Trp Asp 
225                 230                 235                 240 


Phe Gln Phe Pro His Pro Leu Leu Pro Asn Val Glu Phe Val Gly Gly 
                245                 250                 255     


Leu His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu Phe 
            260                 265                 270         


Val Gln Ser Ser Gly Glu Asn Gly Val Val Val Phe Ser Leu Gly Ser 
        275                 280                 285             


Met Val Ser Asn Thr Ser Glu Glu Arg Ala Asn Val Ile Ala Ser Ala 
    290                 295                 300                 


Leu Ala Lys Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Asn Lys 
305                 310                 315                 320 


Pro Asp Thr Leu Gly Leu Asn Thr Arg Leu Tyr Lys Trp Ile Pro Gln 
                325                 330                 335     


Asn Asp Leu Leu Gly His Pro Lys Thr Arg Ala Phe Ile Thr His Gly 
            340                 345                 350         


Gly Ala Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met Val 
        355                 360                 365             


Gly Val Pro Leu Phe Ala Asp Gln Pro Asp Asn Ile Ala His Met Lys 
    370                 375                 380                 


Ala Lys Gly Ala Ala Val Ser Leu Asp Phe His Thr Met Ser Ser Thr 
385                 390                 395                 400 


Asp Leu Leu Asn Ala Leu Lys Thr Val Ile Asn Asp Pro Leu Tyr Lys 
                405                 410                 415     


Glu Asn Ala Met Lys Leu Ser Arg Ile His His Asp Gln Pro Val Lys 
            420                 425                 430         


Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His Lys 
        435                 440                 445             


Gly Ala Lys His Leu Arg Val Ala Ala His Asp Leu Thr Trp Phe Gln 
    450                 455                 460                 


Tyr His Ser Leu Asp 
465                 


<210>  1998
<211>  574
<212>  PRT
<213>  Homo Sapiens

<400>  1998

Glu Asp Asp Ile Ile Ile Ala Thr Lys Asn Gly Lys Val Arg Gly Met 
1               5                   10                  15      


Asn Leu Thr Val Phe Gly Gly Thr Val Thr Ala Phe Leu Gly Ile Pro 
            20                  25                  30          


Tyr Ala Gln Pro Pro Leu Gly Arg Leu Arg Phe Lys Lys Pro Gln Ser 
        35                  40                  45              


Leu Thr Lys Trp Ser Asp Ile Trp Asn Ala Thr Lys Tyr Ala Asn Ser 
    50                  55                  60                  


Cys Cys Gln Asn Ile Asp Gln Ser Phe Pro Gly Phe His Gly Ser Glu 
65                  70                  75                  80  


Met Trp Asn Pro Asn Thr Asp Leu Ser Glu Asp Cys Leu Tyr Leu Asn 
                85                  90                  95      


Val Trp Ile Pro Ala Pro Lys Pro Lys Asn Ala Thr Val Leu Ile Trp 
            100                 105                 110         


Ile Tyr Gly Gly Gly Phe Gln Thr Gly Thr Ser Ser Leu His Val Tyr 
        115                 120                 125             


Asp Gly Lys Phe Leu Ala Arg Val Glu Arg Val Ile Val Val Ser Met 
    130                 135                 140                 


Asn Tyr Arg Val Gly Ala Leu Gly Phe Leu Ala Leu Pro Gly Asn Pro 
145                 150                 155                 160 


Glu Ala Pro Gly Asn Met Gly Leu Phe Asp Gln Gln Leu Ala Leu Gln 
                165                 170                 175     


Trp Val Gln Lys Asn Ile Ala Ala Phe Gly Gly Asn Pro Lys Ser Val 
            180                 185                 190         


Thr Leu Phe Gly Glu Ser Ala Gly Ala Ala Ser Val Ser Leu His Leu 
        195                 200                 205             


Leu Ser Pro Gly Ser His Ser Leu Phe Thr Arg Ala Ile Leu Gln Ser 
    210                 215                 220                 


Gly Ser Phe Asn Ala Pro Trp Ala Val Thr Ser Leu Tyr Glu Ala Arg 
225                 230                 235                 240 


Asn Arg Thr Leu Asn Leu Ala Lys Leu Thr Gly Cys Ser Arg Glu Asn 
                245                 250                 255     


Glu Thr Glu Ile Ile Lys Cys Leu Arg Asn Lys Asp Pro Gln Glu Ile 
            260                 265                 270         


Leu Leu Asn Glu Ala Phe Val Val Pro Tyr Gly Thr Pro Leu Ser Val 
        275                 280                 285             


Asn Phe Gly Pro Thr Val Asp Gly Asp Phe Leu Thr Asp Met Pro Asp 
    290                 295                 300                 


Ile Leu Leu Glu Leu Gly Gln Phe Lys Lys Thr Gln Ile Leu Val Gly 
305                 310                 315                 320 


Val Asn Lys Asp Glu Gly Thr Ala Phe Leu Val Tyr Gly Ala Pro Gly 
                325                 330                 335     


Phe Ser Lys Asp Asn Asn Ser Ile Ile Thr Arg Lys Glu Phe Gln Glu 
            340                 345                 350         


Gly Leu Lys Ile Phe Phe Pro Gly Val Ser Glu Phe Gly Lys Glu Ser 
        355                 360                 365             


Ile Leu Phe His Tyr Thr Asp Trp Val Asp Asp Gln Arg Pro Glu Asn 
    370                 375                 380                 


Tyr Arg Glu Ala Leu Gly Asp Val Val Gly Asp Tyr Asn Phe Ile Cys 
385                 390                 395                 400 


Pro Ala Leu Glu Phe Thr Lys Lys Phe Ser Glu Trp Gly Asn Asn Ala 
                405                 410                 415     


Phe Phe Tyr Tyr Phe Glu His Arg Ser Ser Lys Leu Pro Trp Pro Glu 
            420                 425                 430         


Trp Met Gly Val Met His Gly Tyr Glu Ile Glu Phe Val Phe Gly Leu 
        435                 440                 445             


Pro Leu Glu Arg Arg Asp Asn Tyr Thr Lys Ala Glu Glu Ile Leu Ser 
    450                 455                 460                 


Arg Ser Ile Val Lys Arg Trp Ala Asn Phe Ala Lys Tyr Gly Asn Pro 
465                 470                 475                 480 


Asn Glu Thr Gln Asn Asn Ser Thr Ser Trp Pro Val Phe Lys Ser Thr 
                485                 490                 495     


Glu Gln Lys Tyr Leu Thr Leu Asn Thr Glu Ser Thr Arg Ile Met Thr 
            500                 505                 510         


Lys Leu Arg Ala Gln Gln Cys Arg Phe Trp Thr Ser Phe Phe Pro Lys 
        515                 520                 525             


Val Leu Glu Met Thr Gly Asn Ile Asp Glu Ala Glu Trp Glu Trp Lys 
    530                 535                 540                 


Ala Gly Phe His Arg Trp Asn Asn Tyr Met Met Asp Trp Lys Asn Gln 
545                 550                 555                 560 


Phe Asn Asp Tyr Thr Ser Lys Lys Glu Ser Cys Val Gly Leu 
                565                 570                 


<210>  1999
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  1999

Leu Asp Asn Gly Leu Ala Arg Thr Pro Thr Met Gly Trp Leu His Trp 
1               5                   10                  15      


Glu Arg Phe Met Cys Asn Leu Asp Cys Gln Glu Glu Pro Asp Ser Cys 
            20                  25                  30          


Ile Ser Glu Lys Leu Phe Met Glu Met Ala Glu Leu Met Val Ser Glu 
        35                  40                  45              


Gly Trp Lys Asp Ala Gly Tyr Glu Tyr Leu Cys Ile Asp Asp Cys Trp 
    50                  55                  60                  


Met Ala Pro Gln Arg Asp Ser Glu Gly Arg Leu Gln Ala Asp Pro Gln 
65                  70                  75                  80  


Arg Phe Pro His Gly Ile Arg Gln Leu Ala Asn Tyr Val His Ser Lys 
                85                  90                  95      


Gly Leu Lys Leu Gly Ile Tyr Ala Asp Val Gly Asn Lys Thr Cys Ala 
            100                 105                 110         


Gly Phe Pro Gly Ser Phe Gly Tyr Tyr Asp Ile Asp Ala Gln Thr Phe 
        115                 120                 125             


Ala Asp Trp Gly Val Asp Leu Leu Lys Phe Asp Gly Cys Tyr Cys Asp 
    130                 135                 140                 


Ser Leu Glu Asn Leu Ala Asp Gly Tyr Lys His Met Ser Leu Ala Leu 
145                 150                 155                 160 


Asn Arg Thr Gly Arg Ser Ile Val Tyr Ser Cys Glu Trp Pro Leu Tyr 
                165                 170                 175     


Met Trp Pro Phe Gln Lys Pro Asn Tyr Thr Glu Ile Arg Gln Tyr Cys 
            180                 185                 190         


Asn His Trp Arg Asn Phe Ala Asp Ile Asp Asp Ser Trp Lys Ser Ile 
        195                 200                 205             


Lys Ser Ile Leu Asp Trp Thr Ser Phe Asn Gln Glu Arg Ile Val Asp 
    210                 215                 220                 


Val Ala Gly Pro Gly Gly Trp Asn Asp Pro Asp Met Leu Val Ile Gly 
225                 230                 235                 240 


Asn Phe Gly Leu Ser Trp Asn Gln Gln Val Thr Gln Met Ala Leu Trp 
                245                 250                 255     


Ala Ile Met Ala Ala Pro Leu Phe Met Ser Asn Asp Leu Arg His Ile 
            260                 265                 270         


Ser Pro Gln Ala Lys Ala Leu Leu Gln Asp Lys Asp Val Ile Ala Ile 
        275                 280                 285             


Asn Gln Asp Pro Leu Gly Lys Gln Gly Tyr Gln Leu Arg Gln Gly Asp 
    290                 295                 300                 


Asn Phe Glu Val Trp Glu Arg Pro Leu Ser Gly Leu Ala Trp Ala Val 
305                 310                 315                 320 


Ala Met Ile Asn Arg Gln Glu Ile Gly Gly Pro Arg Ser Tyr Thr Ile 
                325                 330                 335     


Ala Val Ala Ser Leu Gly Lys Gly Val Ala Cys Asn Pro Ala Cys Phe 
            340                 345                 350         


Ile Thr Gln Leu Leu Pro Val Lys Arg Lys Leu Gly Phe Tyr Glu Trp 
        355                 360                 365             


Thr Ser Arg Leu Arg Ser His Ile Asn Pro Thr Gly Thr Val Leu Leu 
    370                 375                 380                 


Gln Leu Glu Asn Thr Met Gln Met Ser Leu Lys Asp Leu Leu 
385                 390                 395             


<210>  2000
<211>  58
<212>  PRT
<213>  Homo Sapiens

<400>  2000

Val Ser Gln Arg Thr Asp Gly Glu Ser Arg Ala His Leu Gly Ala Leu 
1               5                   10                  15      


Leu Ala Arg Tyr Ile Gln Gln Ala Arg Lys Ala Pro Ser Gly Arg Met 
            20                  25                  30          


Ser Ile Val Lys Asn Leu Gln Asn Leu Asp Pro Ser His Arg Ile Ser 
        35                  40                  45              


Asp Arg Asp Tyr Met Gly Trp Met Asp Phe 
    50                  55              


<210>  2001
<211>  755
<212>  PRT
<213>  Homo Sapiens

<400>  2001

Ala Thr Ala Ser Arg Gly Ala Ser Gln Ala Gly Ala Pro Gln Gly Arg 
1               5                   10                  15      


Val Pro Glu Ala Arg Pro Asn Ser Met Val Val Glu His Pro Glu Phe 
            20                  25                  30          


Leu Lys Ala Gly Lys Glu Pro Gly Leu Gln Ile Trp Arg Val Glu Lys 
        35                  40                  45              


Phe Asp Leu Val Pro Val Pro Thr Asn Leu Tyr Gly Asp Phe Phe Thr 
    50                  55                  60                  


Gly Asp Ala Tyr Val Ile Leu Lys Thr Val Gln Leu Arg Asn Gly Asn 
65                  70                  75                  80  


Leu Gln Tyr Asp Leu His Tyr Trp Leu Gly Asn Glu Cys Ser Gln Asp 
                85                  90                  95      


Glu Ser Gly Ala Ala Ala Ile Phe Thr Val Gln Leu Asp Asp Tyr Leu 
            100                 105                 110         


Asn Gly Arg Ala Val Gln His Arg Glu Val Gln Gly Phe Glu Ser Ala 
        115                 120                 125             


Thr Phe Leu Gly Tyr Phe Lys Ser Gly Leu Lys Tyr Lys Lys Gly Gly 
    130                 135                 140                 


Val Ala Ser Gly Phe Lys His Val Val Pro Asn Glu Val Val Val Gln 
145                 150                 155                 160 


Arg Leu Phe Gln Val Lys Gly Arg Arg Val Val Arg Ala Thr Glu Val 
                165                 170                 175     


Pro Val Ser Trp Glu Ser Phe Asn Asn Gly Asp Cys Phe Ile Leu Asp 
            180                 185                 190         


Leu Gly Asn Asn Ile His Gln Trp Cys Gly Ser Asn Ser Asn Arg Tyr 
        195                 200                 205             


Glu Arg Leu Lys Ala Thr Gln Val Ser Lys Gly Ile Arg Asp Asn Glu 
    210                 215                 220                 


Arg Ser Gly Arg Ala Arg Val His Val Ser Glu Glu Gly Thr Glu Pro 
225                 230                 235                 240 


Glu Ala Met Leu Gln Val Leu Gly Pro Lys Pro Ala Leu Pro Ala Gly 
                245                 250                 255     


Thr Glu Asp Thr Ala Lys Glu Asp Ala Ala Asn Arg Lys Leu Ala Lys 
            260                 265                 270         


Leu Tyr Lys Val Ser Asn Gly Ala Gly Thr Met Ser Val Ser Leu Val 
        275                 280                 285             


Ala Asp Glu Asn Pro Phe Ala Gln Gly Ala Leu Lys Ser Glu Asp Cys 
    290                 295                 300                 


Phe Ile Leu Asp His Gly Lys Asp Gly Lys Ile Phe Val Trp Lys Gly 
305                 310                 315                 320 


Lys Gln Ala Asn Thr Glu Glu Arg Lys Ala Ala Leu Lys Thr Ala Ser 
                325                 330                 335     


Asp Phe Ile Thr Lys Met Asp Tyr Pro Lys Gln Thr Gln Val Ser Val 
            340                 345                 350         


Leu Pro Glu Gly Gly Glu Thr Pro Leu Phe Lys Gln Phe Phe Lys Asn 
        355                 360                 365             


Trp Arg Asp Pro Asp Gln Thr Asp Gly Leu Gly Leu Ser Tyr Leu Ser 
    370                 375                 380                 


Ser His Ile Ala Asn Val Glu Arg Val Pro Phe Asp Ala Ala Thr Leu 
385                 390                 395                 400 


His Thr Ser Thr Ala Met Ala Ala Gln His Gly Met Asp Asp Asp Gly 
                405                 410                 415     


Thr Gly Gln Lys Gln Ile Trp Arg Ile Glu Gly Ser Asn Lys Val Pro 
            420                 425                 430         


Val Asp Pro Ala Thr Tyr Gly Gln Phe Tyr Gly Gly Asp Ser Tyr Ile 
        435                 440                 445             


Ile Leu Tyr Asn Tyr Arg His Gly Gly Arg Gln Gly Gln Ile Ile Tyr 
    450                 455                 460                 


Asn Trp Gln Gly Ala Gln Ser Thr Gln Asp Glu Val Ala Ala Ser Ala 
465                 470                 475                 480 


Ile Leu Thr Ala Gln Leu Asp Glu Glu Leu Gly Gly Thr Pro Val Gln 
                485                 490                 495     


Ser Arg Val Val Gln Gly Lys Glu Pro Ala His Leu Met Ser Leu Phe 
            500                 505                 510         


Gly Gly Lys Pro Met Ile Ile Tyr Lys Gly Gly Thr Ser Arg Glu Gly 
        515                 520                 525             


Gly Gln Thr Ala Pro Ala Ser Thr Arg Leu Phe Gln Val Arg Ala Asn 
    530                 535                 540                 


Ser Ala Gly Ala Thr Arg Ala Val Glu Val Leu Pro Lys Ala Gly Ala 
545                 550                 555                 560 


Leu Asn Ser Asn Asp Ala Phe Val Leu Lys Thr Pro Ser Ala Ala Tyr 
                565                 570                 575     


Leu Trp Val Gly Thr Gly Ala Ser Glu Ala Glu Lys Thr Gly Ala Gln 
            580                 585                 590         


Glu Leu Leu Arg Val Leu Arg Ala Gln Pro Val Gln Val Ala Glu Gly 
        595                 600                 605             


Ser Glu Pro Asp Gly Phe Trp Glu Ala Leu Gly Gly Lys Ala Ala Tyr 
    610                 615                 620                 


Arg Thr Ser Pro Arg Leu Lys Asp Lys Lys Met Asp Ala His Pro Pro 
625                 630                 635                 640 


Arg Leu Phe Ala Cys Ser Asn Lys Ile Gly Arg Phe Val Ile Glu Glu 
                645                 650                 655     


Val Pro Gly Glu Leu Met Gln Glu Asp Leu Ala Thr Asp Asp Val Met 
            660                 665                 670         


Leu Leu Asp Thr Trp Asp Gln Val Phe Val Trp Val Gly Lys Asp Ser 
        675                 680                 685             


Gln Glu Glu Glu Lys Thr Glu Ala Leu Thr Ser Ala Lys Arg Tyr Ile 
    690                 695                 700                 


Glu Thr Asp Pro Ala Asn Arg Asp Arg Arg Thr Pro Ile Thr Val Val 
705                 710                 715                 720 


Lys Gln Gly Phe Glu Pro Pro Ser Phe Val Gly Trp Phe Leu Gly Trp 
                725                 730                 735     


Asp Asp Asp Tyr Trp Ser Val Asp Pro Leu Asp Arg Ala Met Ala Glu 
            740                 745                 750         


Leu Ala Ala 
        755 


<210>  2002
<211>  509
<212>  PRT
<213>  Homo Sapiens

<400>  2002

Lys Ile Gln Ile Gln Arg Ser Gly His Leu Asn Leu Tyr Leu Leu Leu 
1               5                   10                  15      


Asp Cys Ser Gln Ser Val Ser Glu Asn Asp Phe Leu Ile Phe Lys Glu 
            20                  25                  30          


Ser Ala Ser Leu Met Val Asp Arg Ile Phe Ser Phe Glu Ile Asn Val 
        35                  40                  45              


Ser Val Ala Ile Ile Thr Phe Ala Ser Glu Pro Lys Val Leu Met Ser 
    50                  55                  60                  


Val Leu Asn Asp Asn Ser Arg Asp Met Thr Glu Val Ile Ser Ser Leu 
65                  70                  75                  80  


Glu Asn Ala Asn Tyr Lys Asp His Glu Asn Gly Thr Gly Thr Asn Thr 
                85                  90                  95      


Tyr Ala Ala Leu Asn Ser Val Tyr Leu Met Met Asn Asn Gln Met Arg 
            100                 105                 110         


Leu Leu Gly Met Glu Thr Met Ala Trp Gln Glu Ile Arg His Ala Ile 
        115                 120                 125             


Ile Leu Leu Thr Asp Gly Lys Ser Asn Met Gly Gly Ser Pro Lys Thr 
    130                 135                 140                 


Ala Val Asp His Ile Arg Glu Ile Leu Asn Ile Asn Gln Lys Arg Asn 
145                 150                 155                 160 


Asp Tyr Leu Asp Ile Tyr Ala Ile Gly Val Gly Lys Leu Asp Val Asp 
                165                 170                 175     


Trp Arg Glu Leu Asn Glu Leu Gly Ser Lys Lys Asp Gly Glu Arg His 
            180                 185                 190         


Ala Phe Ile Leu Gln Asp Thr Lys Ala Leu His Gln Val Phe Glu His 
        195                 200                 205             


Met Leu Asp Val Ser Lys Leu Thr Asp Thr Ile Cys Gly Val Gly Asn 
    210                 215                 220                 


Met Ser Ala Asn Ala Ser Asp Gln Glu Arg Thr Pro Trp His Val Thr 
225                 230                 235                 240 


Ile Lys Pro Lys Ser Gln Glu Thr Cys Arg Gly Ala Leu Ile Ser Asp 
                245                 250                 255     


Gln Trp Val Leu Thr Ala Ala His Cys Phe Arg Asp Gly Asn Asp His 
            260                 265                 270         


Ser Leu Trp Arg Val Asn Val Gly Asp Pro Lys Ser Gln Trp Gly Lys 
        275                 280                 285             


Glu Phe Leu Ile Glu Lys Ala Val Ile Ser Pro Gly Phe Asp Val Phe 
    290                 295                 300                 


Ala Lys Lys Asn Gln Gly Ile Leu Glu Phe Tyr Gly Asp Asp Ile Ala 
305                 310                 315                 320 


Leu Leu Lys Leu Ala Gln Lys Val Lys Met Ser Thr His Ala Arg Pro 
                325                 330                 335     


Ile Cys Leu Pro Cys Thr Met Glu Ala Asn Leu Ala Leu Arg Arg Pro 
            340                 345                 350         


Gln Gly Ser Thr Cys Arg Asp His Glu Asn Glu Leu Leu Asn Lys Gln 
        355                 360                 365             


Ser Val Pro Ala His Phe Val Ala Leu Asn Gly Ser Lys Leu Asn Ile 
    370                 375                 380                 


Asn Leu Lys Met Gly Val Glu Trp Thr Ser Cys Ala Glu Val Val Ser 
385                 390                 395                 400 


Gln Glu Lys Thr Met Phe Pro Asn Leu Thr Asp Val Arg Glu Val Val 
                405                 410                 415     


Thr Asp Gln Phe Leu Cys Ser Gly Thr Gln Glu Asp Glu Ser Pro Cys 
            420                 425                 430         


Lys Gly Glu Ser Gly Gly Ala Val Phe Leu Glu Arg Arg Phe Arg Phe 
        435                 440                 445             


Phe Gln Val Gly Leu Val Ser Trp Gly Leu Tyr Asn Pro Cys Leu Gly 
    450                 455                 460                 


Ser Ala Asp Lys Asn Ser Arg Lys Arg Ala Pro Arg Ser Lys Val Pro 
465                 470                 475                 480 


Pro Pro Arg Asp Phe His Ile Asn Leu Phe Arg Met Gln Pro Trp Leu 
                485                 490                 495     


Arg Gln His Leu Gly Asp Val Leu Asn Phe Leu Pro Leu 
            500                 505                 


<210>  2003
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  2003

Met Thr Cys Lys Met Ser Gln Leu Glu Arg Asn Ile Glu Thr Ile Ile 
1               5                   10                  15      


Asn Thr Phe His Gln Tyr Ser Val Lys Leu Gly His Pro Asp Thr Leu 
            20                  25                  30          


Asn Gln Gly Glu Phe Lys Glu Leu Val Arg Lys Asp Leu Gln Asn Phe 
        35                  40                  45              


Leu Lys Lys Glu Asn Lys Asn Glu Lys Val Ile Glu His Ile Met Glu 
    50                  55                  60                  


Asp Leu Asp Thr Asn Ala Asp Lys Gln Leu Ser Phe Glu Glu Phe Ile 
65                  70                  75                  80  


Met Leu Met Ala Arg Leu Thr Trp Ala Ser His Glu Lys Met His Glu 
                85                  90                  95      


Gly Asp Glu Gly Pro Gly His His His Lys Pro Gly Leu Gly Glu Gly 
            100                 105                 110         


Thr Pro 
        


<210>  2004
<211>  448
<212>  PRT
<213>  Homo Sapiens

<400>  2004

Ala Asp Gln Arg Arg Asp Phe Ile Asp Ile Glu Ser Lys Phe Ala Leu 
1               5                   10                  15      


Arg Thr Pro Glu Asp Thr Ala Glu Asp Thr Cys His Leu Ile Pro Gly 
            20                  25                  30          


Val Ala Glu Ser Val Ala Thr Cys His Phe Asn His Ser Ser Lys Thr 
        35                  40                  45              


Phe Met Val Ile His Gly Trp Thr Val Thr Gly Met Tyr Glu Ser Trp 
    50                  55                  60                  


Val Pro Lys Leu Val Ala Ala Leu Tyr Lys Arg Glu Pro Asp Ser Asn 
65                  70                  75                  80  


Val Ile Val Val Asp Trp Leu Ser Arg Ala Gln Glu His Tyr Pro Val 
                85                  90                  95      


Ser Ala Gly Tyr Thr Lys Leu Val Gly Gln Asp Val Ala Arg Phe Ile 
            100                 105                 110         


Asn Trp Met Glu Glu Glu Phe Asn Tyr Pro Leu Asp Asn Val His Leu 
        115                 120                 125             


Leu Gly Tyr Ser Leu Gly Ala His Ala Ala Gly Ile Ala Gly Ser Leu 
    130                 135                 140                 


Thr Asn Lys Lys Val Asn Arg Ile Thr Gly Leu Asp Pro Ala Gly Pro 
145                 150                 155                 160 


Asn Phe Glu Tyr Ala Glu Ala Pro Ser Arg Leu Ser Pro Asp Asp Ala 
                165                 170                 175     


Asp Phe Val Asp Val Leu His Thr Phe Thr Arg Gly Ser Pro Gly Arg 
            180                 185                 190         


Ser Ile Gly Ile Gln Lys Pro Val Gly His Val Asp Ile Tyr Pro Asn 
        195                 200                 205             


Gly Gly Thr Phe Gln Pro Gly Cys Asn Ile Gly Glu Ala Ile Arg Val 
    210                 215                 220                 


Ile Ala Glu Arg Gly Leu Gly Asp Val Asp Gln Leu Val Lys Cys Ser 
225                 230                 235                 240 


His Glu Arg Ser Ile His Leu Phe Ile Asp Ser Leu Leu Asn Glu Glu 
                245                 250                 255     


Asn Pro Ser Lys Ala Tyr Arg Cys Ser Ser Lys Glu Ala Phe Glu Lys 
            260                 265                 270         


Gly Leu Cys Leu Ser Cys Arg Lys Asn Arg Cys Asn Asn Leu Gly Tyr 
        275                 280                 285             


Glu Ile Ser Lys Val Arg Ala Lys Arg Ser Ser Lys Met Tyr Leu Lys 
    290                 295                 300                 


Thr Arg Ser Gln Met Pro Tyr Lys Val Phe His Tyr Gln Val Lys Ile 
305                 310                 315                 320 


His Phe Ser Gly Thr Glu Ser Glu Thr His Thr Asn Gln Ala Phe Glu 
                325                 330                 335     


Ile Ser Leu Tyr Gly Thr Val Ala Glu Ser Glu Asn Ile Pro Phe Thr 
            340                 345                 350         


Leu Pro Glu Val Ser Thr Asn Lys Thr Tyr Ser Phe Leu Ile Tyr Thr 
        355                 360                 365             


Glu Val Asp Ile Gly Glu Leu Leu Met Leu Lys Leu Lys Trp Lys Ser 
    370                 375                 380                 


Asp Ser Tyr Phe Ser Trp Ser Asp Trp Trp Ser Ser Pro Gly Phe Ala 
385                 390                 395                 400 


Ile Gln Lys Ile Arg Val Lys Ala Gly Glu Thr Gln Lys Lys Val Ile 
                405                 410                 415     


Phe Cys Ser Arg Glu Lys Val Ser His Leu Gln Lys Gly Lys Ala Pro 
            420                 425                 430         


Ala Val Phe Val Lys Cys His Asp Lys Ser Leu Asn Lys Lys Ser Gly 
        435                 440                 445             


<210>  2005
<211>  441
<212>  PRT
<213>  Homo Sapiens

<400>  2005

Thr Leu Glu Lys Asn Val Leu Val Val Ser Val Val Thr Pro Gly Cys 
1               5                   10                  15      


Asn Gln Leu Pro Thr Leu Glu Ser Val Glu Asn Tyr Thr Leu Thr Ile 
            20                  25                  30          


Asn Asp Asp Gln Cys Leu Leu Leu Ser Glu Thr Val Trp Gly Ala Leu 
        35                  40                  45              


Arg Gly Leu Glu Thr Phe Ser Gln Leu Val Trp Lys Ser Ala Glu Gly 
    50                  55                  60                  


Thr Phe Phe Ile Asn Lys Thr Glu Ile Glu Asp Phe Pro Arg Phe Pro 
65                  70                  75                  80  


His Arg Gly Leu Leu Leu Asp Thr Ser Arg His Tyr Leu Pro Leu Ser 
                85                  90                  95      


Ser Ile Leu Asp Thr Leu Asp Val Met Ala Tyr Asn Lys Leu Asn Val 
            100                 105                 110         


Phe His Trp His Leu Val Asp Asp Pro Ser Phe Pro Tyr Glu Ser Phe 
        115                 120                 125             


Thr Phe Pro Glu Leu Met Arg Lys Gly Ser Tyr Asn Pro Val Thr His 
    130                 135                 140                 


Ile Tyr Thr Ala Gln Asp Val Lys Glu Val Ile Glu Tyr Ala Arg Leu 
145                 150                 155                 160 


Arg Gly Ile Arg Val Leu Ala Glu Phe Asp Thr Pro Gly His Thr Leu 
                165                 170                 175     


Ser Trp Gly Pro Gly Ile Pro Gly Leu Leu Thr Pro Cys Tyr Ser Gly 
            180                 185                 190         


Ser Glu Pro Ser Gly Thr Phe Gly Pro Val Asn Pro Ser Leu Asn Asn 
        195                 200                 205             


Thr Tyr Glu Phe Met Ser Thr Phe Phe Leu Glu Val Ser Ser Val Phe 
    210                 215                 220                 


Pro Asp Phe Tyr Leu His Leu Gly Gly Asp Glu Val Asp Phe Thr Cys 
225                 230                 235                 240 


Trp Lys Ser Asn Pro Glu Ile Gln Asp Phe Met Arg Lys Lys Gly Phe 
                245                 250                 255     


Gly Glu Asp Phe Lys Gln Leu Glu Ser Phe Tyr Ile Gln Thr Leu Leu 
            260                 265                 270         


Asp Ile Val Ser Ser Tyr Gly Lys Gly Tyr Val Val Trp Gln Glu Val 
        275                 280                 285             


Phe Asp Asn Lys Val Lys Ile Gln Pro Asp Thr Ile Ile Gln Val Trp 
    290                 295                 300                 


Arg Glu Asp Ile Pro Val Asn Tyr Met Lys Glu Leu Glu Leu Val Thr 
305                 310                 315                 320 


Lys Ala Gly Phe Arg Ala Leu Leu Ser Ala Pro Trp Tyr Leu Asn Arg 
                325                 330                 335     


Ile Ser Tyr Gly Pro Asp Trp Lys Asp Phe Tyr Val Val Glu Pro Leu 
            340                 345                 350         


Ala Phe Glu Gly Thr Pro Glu Gln Lys Ala Leu Val Ile Gly Gly Glu 
        355                 360                 365             


Ala Cys Met Trp Gly Glu Tyr Val Asp Asn Thr Asn Leu Val Pro Arg 
    370                 375                 380                 


Leu Trp Pro Arg Ala Gly Ala Val Ala Glu Arg Leu Trp Ser Asn Lys 
385                 390                 395                 400 


Leu Thr Ser Asp Leu Thr Phe Ala Tyr Glu Arg Leu Ser His Phe Arg 
                405                 410                 415     


Cys Glu Leu Leu Arg Arg Gly Val Gln Ala Gln Pro Leu Asn Val Gly 
            420                 425                 430         


Phe Cys Glu Gln Glu Phe Glu Gln Thr 
        435                 440     


<210>  2006
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  2006

Ile Val Gly Gly Trp Glu Cys Glu Gln His Ser Gln Pro Trp Gln Ala 
1               5                   10                  15      


Ala Leu Tyr His Phe Ser Thr Phe Gln Cys Gly Gly Ile Leu Val His 
            20                  25                  30          


Arg Gln Trp Val Leu Thr Ala Ala His Cys Ile Ser Asp Asn Tyr Gln 
        35                  40                  45              


Leu Trp Leu Gly Arg His Asn Leu Phe Asp Asp Glu Asn Thr Ala Gln 
    50                  55                  60                  


Phe Val His Val Ser Glu Ser Phe Pro His Pro Gly Phe Asn Met Ser 
65                  70                  75                  80  


Leu Leu Glu Asn His Thr Arg Gln Ala Asp Glu Asp Tyr Ser His Asp 
                85                  90                  95      


Leu Met Leu Leu Arg Leu Thr Glu Pro Ala Asp Thr Ile Thr Asp Ala 
            100                 105                 110         


Val Lys Val Val Glu Leu Pro Thr Gln Glu Pro Glu Val Gly Ser Thr 
        115                 120                 125             


Cys Leu Ala Ser Gly Trp Gly Ser Ile Glu Pro Glu Asn Phe Ser Phe 
    130                 135                 140                 


Pro Asp Asp Leu Gln Cys Val Asp Leu Lys Ile Leu Pro Asn Asp Glu 
145                 150                 155                 160 


Cys Lys Lys Val His Val Gln Lys Val Thr Asp Phe Met Leu Cys Val 
                165                 170                 175     


Gly His Leu Glu Gly Gly Lys Asp Thr Cys Val Gly Asp Ser Gly Gly 
            180                 185                 190         


Pro Leu Met Cys Asp Gly Val Leu Gln Gly Val Thr Ser Trp Gly Tyr 
        195                 200                 205             


Val Pro Cys Gly Thr Pro Asn Lys Pro Ser Val Ala Val Arg Val Leu 
    210                 215                 220                 


Ser Tyr Val Lys Trp Ile Glu Asp Thr Ile Ala Glu Asn Ser 
225                 230                 235             


<210>  2007
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2007

Ser His Phe Asn Pro Leu Ser Leu Glu Glu Leu Gly Ser Asn Thr Gly 
1               5                   10                  15      


Ile Gln Val Phe Asn Gln Ile Val Lys Ser Arg Pro His Asp Asn Ile 
            20                  25                  30          


Val Ile Ser Pro His Gly Ile Ala Ser Val Leu Gly Met Leu Gln Leu 
        35                  40                  45              


Gly Ala Asp Gly Arg Thr Lys Lys Gln Leu Ala Met Val Met Arg Tyr 
    50                  55                  60                  


Gly Val Asn Gly Val Gly Lys Ile Leu Lys Lys Ile Asn Lys Ala Ile 
65                  70                  75                  80  


Val Ser Lys Lys Asn Lys Asp Ile Val Thr Val Ala Asn Ala Val Phe 
                85                  90                  95      


Val Lys Asn Ala Ser Glu Ile Glu Val Pro Phe Val Thr Arg Asn Lys 
            100                 105                 110         


Asp Val Phe Gln Cys Glu Val Arg Asn Val Asn Phe Glu Asp Pro Ala 
        115                 120                 125             


Ser Ala Cys Asp Ser Ile Asn Ala Trp Val Lys Asn Glu Thr Arg Asp 
    130                 135                 140                 


Met Ile Asp Asn Leu Leu Ser Pro Asp Leu Ile Asp Gly Val Leu Thr 
145                 150                 155                 160 


Arg Leu Val Leu Val Asn Ala Val Tyr Phe Lys Gly Leu Trp Lys Ser 
                165                 170                 175     


Arg Phe Gln Pro Glu Asn Thr Lys Lys Arg Thr Phe Val Ala Ala Asp 
            180                 185                 190         


Gly Lys Ser Tyr Gln Val Pro Met Leu Ala Gln Leu Ser Val Phe Arg 
        195                 200                 205             


Cys Gly Ser Thr Ser Ala Pro Asn Asp Leu Trp Tyr Asn Phe Ile Glu 
    210                 215                 220                 


Leu Pro Tyr His Gly Glu Ser Ile Ser Met Leu Ile Ala Leu Pro Thr 
225                 230                 235                 240 


Glu Ser Ser Thr Pro Leu Ser Ala Ile Ile Pro His Ile Ser Thr Lys 
                245                 250                 255     


Thr Ile Asp Ser Trp Met Ser Ile Met Val Pro Lys Arg Val Gln Val 
            260                 265                 270         


Ile Leu Pro Lys Phe Thr Ala Val Ala Gln Thr Asp Leu Lys Glu Pro 
        275                 280                 285             


Leu Lys Val Leu Gly Ile Thr Asp Met Phe Asp Ser Ser Lys Ala Asn 
    290                 295                 300                 


Phe Ala Lys Ile Thr Arg Ser Glu Asn Leu His Val Ser His Ile Leu 
305                 310                 315                 320 


Gln Lys Ala Lys Ile Glu Val Ser Glu Asp Gly Thr Lys Ala Ser Ala 
                325                 330                 335     


Ala Thr Thr Ala Ile Leu Ile Ala Arg Ser Ser Pro Pro Trp Phe Ile 
            340                 345                 350         


Val Asp Arg Pro Phe Leu Phe Phe Ile Arg His Asn Pro Thr Gly Ala 
        355                 360                 365             


Val Leu Phe Met Gly Gln Ile Asn Lys Pro 
    370                 375             


<210>  2008
<211>  379
<212>  PRT
<213>  Homo Sapiens

<400>  2008

Leu Phe Gly Lys Leu His Pro Gly Ser Pro Glu Val Thr Met Asn Ile 
1               5                   10                  15      


Ser Gln Met Ile Thr Tyr Trp Gly Tyr Pro Asn Glu Glu Tyr Glu Val 
            20                  25                  30          


Val Thr Glu Asp Gly Tyr Ile Leu Glu Val Asn Arg Ile Pro Tyr Gly 
        35                  40                  45              


Lys Lys Asn Ser Gly Asn Thr Gly Gln Arg Pro Val Val Phe Leu Gln 
    50                  55                  60                  


His Gly Leu Leu Ala Ser Ala Thr Asn Trp Ile Ser Asn Leu Pro Asn 
65                  70                  75                  80  


Asn Ser Leu Ala Phe Ile Leu Ala Asp Ala Gly Tyr Asp Val Trp Leu 
                85                  90                  95      


Gly Asn Ser Arg Gly Asn Thr Trp Ala Arg Arg Asn Leu Tyr Tyr Ser 
            100                 105                 110         


Pro Asp Ser Val Glu Phe Trp Ala Phe Ser Phe Asp Glu Met Ala Lys 
        115                 120                 125             


Tyr Asp Leu Pro Ala Thr Ile Asp Phe Ile Val Lys Lys Ala Gly Gln 
    130                 135                 140                 


Lys Gln Leu His Tyr Val Gly His Ser Gln Gly Thr Thr Ile Gly Phe 
145                 150                 155                 160 


Ile Ala Phe Ser Thr Asn Pro Ser Leu Ala Lys Arg Ile Lys Thr Phe 
                165                 170                 175     


Tyr Ala Leu Ala Pro Val Ala Thr Val Lys Tyr Thr Lys Ser Leu Ile 
            180                 185                 190         


Asn Lys Leu Arg Phe Val Pro Gln Ser Leu Phe Lys Phe Ile Phe Gly 
        195                 200                 205             


Asp Lys Ile Phe Tyr Pro His Asn Phe Phe Asp Gln Phe Leu Ala Thr 
    210                 215                 220                 


Glu Val Cys Ser Arg Glu Met Leu Asn Leu Leu Cys Ser Asn Ala Leu 
225                 230                 235                 240 


Phe Ile Ile Cys Gly Phe Asp Ser Lys Asn Phe Asn Thr Ser Arg Leu 
                245                 250                 255     


Asp Val Tyr Leu Ser His Asn Pro Ala Gly Thr Ser Val Gln Asn Met 
            260                 265                 270         


Phe His Trp Thr Gln Ala Val Lys Ser Gly Lys Phe Gln Ala Tyr Asp 
        275                 280                 285             


Trp Gly Ser Pro Val Gln Asn Arg Met His Tyr Asp Gln Ser Gln Pro 
    290                 295                 300                 


Pro Tyr Tyr Asn Val Thr Ala Met Asn Val Pro Ile Ala Val Trp Asn 
305                 310                 315                 320 


Gly Gly Lys Asp Leu Leu Ala Asp Pro Gln Asp Val Gly Leu Leu Leu 
                325                 330                 335     


Pro Lys Leu Pro Asn Leu Ile Tyr His Lys Glu Ile Pro Phe Tyr Asn 
            340                 345                 350         


His Leu Asp Phe Ile Trp Ala Met Asp Ala Pro Gln Glu Val Tyr Asn 
        355                 360                 365             


Asp Ile Val Ser Met Ile Ser Glu Asp Lys Lys 
    370                 375                 


<210>  2009
<211>  491
<212>  PRT
<213>  Homo Sapiens

<400>  2009

Asp Ala Pro Glu Glu Glu Asp His Val Leu Val Leu Arg Lys Ser Asn 
1               5                   10                  15      


Phe Ala Glu Ala Leu Ala Ala His Lys Tyr Leu Leu Val Glu Phe Tyr 
            20                  25                  30          


Ala Pro Trp Cys Gly His Cys Lys Ala Leu Ala Pro Glu Tyr Ala Lys 
        35                  40                  45              


Ala Ala Gly Lys Leu Lys Ala Glu Gly Ser Glu Ile Arg Leu Ala Lys 
    50                  55                  60                  


Val Asp Ala Thr Glu Glu Ser Asp Leu Ala Gln Gln Tyr Gly Val Arg 
65                  70                  75                  80  


Gly Tyr Pro Thr Ile Lys Phe Phe Arg Asn Gly Asp Thr Ala Ser Pro 
                85                  90                  95      


Lys Glu Tyr Thr Ala Gly Arg Glu Ala Asp Asp Ile Val Asn Trp Leu 
            100                 105                 110         


Lys Lys Arg Thr Gly Pro Ala Ala Thr Thr Leu Pro Asp Gly Ala Ala 
        115                 120                 125             


Ala Glu Ser Leu Val Glu Ser Ser Glu Val Ala Val Ile Gly Phe Phe 
    130                 135                 140                 


Lys Asp Val Glu Ser Asp Ser Ala Lys Gln Phe Leu Gln Ala Ala Glu 
145                 150                 155                 160 


Ala Ile Asp Asp Ile Pro Phe Gly Ile Thr Ser Asn Ser Asp Val Phe 
                165                 170                 175     


Ser Lys Tyr Gln Leu Asp Lys Asp Gly Val Val Leu Phe Lys Lys Phe 
            180                 185                 190         


Asp Glu Gly Arg Asn Asn Phe Glu Gly Glu Val Thr Lys Glu Asn Leu 
        195                 200                 205             


Leu Asp Phe Ile Lys His Asn Gln Leu Pro Leu Val Ile Glu Phe Thr 
    210                 215                 220                 


Glu Gln Thr Ala Pro Lys Ile Phe Gly Gly Glu Ile Lys Thr His Ile 
225                 230                 235                 240 


Leu Leu Phe Leu Pro Lys Ser Val Ser Asp Tyr Asp Gly Lys Leu Ser 
                245                 250                 255     


Asn Phe Lys Thr Ala Ala Glu Ser Phe Lys Gly Lys Ile Leu Phe Ile 
            260                 265                 270         


Phe Ile Asp Ser Asp His Thr Asp Asn Gln Arg Ile Leu Glu Phe Phe 
        275                 280                 285             


Gly Leu Lys Lys Glu Glu Cys Pro Ala Val Arg Leu Ile Thr Leu Glu 
    290                 295                 300                 


Glu Glu Met Thr Lys Tyr Lys Pro Glu Ser Glu Glu Leu Thr Ala Glu 
305                 310                 315                 320 


Arg Ile Thr Glu Phe Cys His Arg Phe Leu Glu Gly Lys Ile Lys Pro 
                325                 330                 335     


His Leu Met Ser Gln Glu Leu Pro Glu Asp Trp Asp Lys Gln Pro Val 
            340                 345                 350         


Lys Val Leu Val Gly Lys Asn Phe Glu Asp Val Ala Phe Asp Glu Lys 
        355                 360                 365             


Lys Asn Val Phe Val Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys 
    370                 375                 380                 


Gln Leu Ala Pro Ile Trp Asp Lys Leu Gly Glu Thr Tyr Lys Asp His 
385                 390                 395                 400 


Glu Asn Ile Val Ile Ala Lys Met Asp Ser Thr Ala Asn Glu Val Glu 
                405                 410                 415     


Ala Val Lys Val His Ser Phe Pro Thr Leu Lys Phe Phe Pro Ala Ser 
            420                 425                 430         


Ala Asp Arg Thr Val Ile Asp Tyr Asn Gly Glu Arg Thr Leu Asp Gly 
        435                 440                 445             


Phe Lys Lys Phe Leu Glu Ser Gly Gly Gln Asp Gly Ala Gly Asp Asp 
    450                 455                 460                 


Asp Asp Leu Glu Asp Leu Glu Glu Ala Glu Glu Pro Asp Met Glu Glu 
465                 470                 475                 480 


Asp Asp Asp Gln Lys Ala Val Lys Asp Glu Leu 
                485                 490     


<210>  2010
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  2010

Ile Val Gly Gly Trp Glu Cys Glu Lys His Ser Gln Pro Trp Gln Val 
1               5                   10                  15      


Leu Val Ala Ser Arg Gly Arg Ala Val Cys Gly Gly Val Leu Val His 
            20                  25                  30          


Pro Gln Trp Val Leu Thr Ala Ala His Cys Ile Arg Asn Lys Ser Val 
        35                  40                  45              


Ile Leu Leu Gly Arg His Ser Leu Phe His Pro Glu Asp Thr Gly Gln 
    50                  55                  60                  


Val Phe Gln Val Ser His Ser Phe Pro His Pro Leu Tyr Asp Met Ser 
65                  70                  75                  80  


Leu Leu Lys Asn Arg Phe Leu Arg Pro Gly Asp Asp Ser Ser His Asp 
                85                  90                  95      


Leu Met Leu Leu Arg Leu Ser Glu Pro Ala Glu Leu Thr Asp Ala Val 
            100                 105                 110         


Lys Val Met Asp Leu Pro Thr Gln Glu Pro Ala Leu Gly Thr Thr Cys 
        115                 120                 125             


Tyr Ala Ser Gly Trp Gly Ser Ile Glu Pro Glu Glu Phe Leu Thr Pro 
    130                 135                 140                 


Lys Lys Leu Gln Cys Val Asp Leu His Val Ile Ser Asn Asp Val Cys 
145                 150                 155                 160 


Ala Gln Val His Pro Gln Lys Val Thr Lys Phe Met Leu Cys Ala Gly 
                165                 170                 175     


Arg Trp Thr Gly Gly Lys Ser Thr Cys Ser Gly Asp Ser Gly Gly Pro 
            180                 185                 190         


Leu Val Cys Asn Gly Val Leu Gln Gly Ile Thr Ser Trp Gly Ser Glu 
        195                 200                 205             


Pro Cys Ala Leu Pro Glu Arg Pro Ser Leu Tyr Thr Lys Val Val His 
    210                 215                 220                 


Tyr Arg Lys Trp Ile Lys Asp Thr Ile Val Ala Asn Pro 
225                 230                 235         


<210>  2011
<211>  348
<212>  PRT
<213>  Homo Sapiens

<400>  2011

Gly Pro Ile Pro Glu Val Leu Lys Asn Tyr Met Asp Ala Gln Tyr Tyr 
1               5                   10                  15      


Gly Glu Ile Gly Ile Gly Thr Pro Pro Gln Cys Phe Thr Val Val Phe 
            20                  25                  30          


Asp Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Ile His Cys Lys Leu 
        35                  40                  45              


Leu Asp Ile Ala Cys Trp Ile His His Lys Tyr Asn Ser Asp Lys Ser 
    50                  55                  60                  


Ser Thr Tyr Val Lys Asn Gly Thr Ser Phe Asp Ile His Tyr Gly Ser 
65                  70                  75                  80  


Gly Ser Leu Ser Gly Tyr Leu Ser Gln Asp Thr Val Ser Val Pro Cys 
                85                  90                  95      


Gln Ser Ala Ser Ser Ala Ser Ala Leu Gly Gly Val Lys Val Glu Arg 
            100                 105                 110         


Gln Val Phe Gly Glu Ala Thr Lys Gln Pro Gly Ile Thr Phe Ile Ala 
        115                 120                 125             


Ala Lys Phe Asp Gly Ile Leu Gly Met Ala Tyr Pro Arg Ile Ser Val 
    130                 135                 140                 


Asn Asn Val Leu Pro Val Phe Asp Asn Leu Met Gln Gln Lys Leu Val 
145                 150                 155                 160 


Asp Gln Asn Ile Phe Ser Phe Tyr Leu Ser Arg Asp Pro Asp Ala Gln 
                165                 170                 175     


Pro Gly Gly Glu Leu Met Leu Gly Gly Thr Asp Ser Lys Tyr Tyr Lys 
            180                 185                 190         


Gly Ser Leu Ser Tyr Leu Asn Val Thr Arg Lys Ala Tyr Trp Gln Val 
        195                 200                 205             


His Leu Asp Gln Val Glu Val Ala Ser Gly Leu Thr Leu Cys Lys Glu 
    210                 215                 220                 


Gly Cys Glu Ala Ile Val Asp Thr Gly Thr Ser Leu Met Val Gly Pro 
225                 230                 235                 240 


Val Asp Glu Val Arg Glu Leu Gln Lys Ala Ile Gly Ala Val Pro Leu 
                245                 250                 255     


Ile Gln Gly Glu Tyr Met Ile Pro Cys Glu Lys Val Ser Thr Leu Pro 
            260                 265                 270         


Ala Ile Thr Leu Lys Leu Gly Gly Lys Gly Tyr Lys Leu Ser Pro Glu 
        275                 280                 285             


Asp Tyr Thr Leu Lys Val Ser Gln Ala Gly Lys Thr Leu Cys Leu Ser 
    290                 295                 300                 


Gly Phe Met Gly Met Asp Ile Pro Pro Pro Ser Gly Pro Leu Trp Ile 
305                 310                 315                 320 


Leu Gly Asp Val Phe Ile Gly Arg Tyr Tyr Thr Val Phe Asp Arg Asp 
                325                 330                 335     


Asn Asn Arg Val Gly Phe Ala Glu Ala Ala Arg Leu 
            340                 345             


<210>  2012
<211>  338
<212>  PRT
<213>  Homo Sapiens

<400>  2012

Ser Thr Val His Glu Ile Leu Cys Lys Leu Ser Leu Glu Gly Asp His 
1               5                   10                  15      


Ser Thr Pro Pro Ser Ala Tyr Gly Ser Val Lys Ala Tyr Thr Asn Phe 
            20                  25                  30          


Asp Ala Glu Arg Asp Ala Leu Asn Ile Glu Thr Ala Ile Lys Thr Lys 
        35                  40                  45              


Gly Val Asp Glu Val Thr Ile Val Asn Ile Leu Thr Asn Arg Ser Asn 
    50                  55                  60                  


Ala Gln Arg Gln Asp Ile Ala Phe Ala Tyr Gln Arg Arg Thr Lys Lys 
65                  70                  75                  80  


Glu Leu Ala Ser Ala Leu Lys Ser Ala Leu Ser Gly His Leu Glu Thr 
                85                  90                  95      


Val Ile Leu Gly Leu Leu Lys Thr Pro Ala Gln Tyr Asp Ala Ser Glu 
            100                 105                 110         


Leu Lys Ala Ser Met Lys Gly Leu Gly Thr Asp Glu Asp Ser Leu Ile 
        115                 120                 125             


Glu Ile Ile Cys Ser Arg Thr Asn Gln Glu Leu Gln Glu Ile Asn Arg 
    130                 135                 140                 


Val Tyr Lys Glu Met Tyr Lys Thr Asp Leu Glu Lys Asp Ile Ile Ser 
145                 150                 155                 160 


Asp Thr Ser Gly Asp Phe Arg Lys Leu Met Val Ala Leu Ala Lys Gly 
                165                 170                 175     


Arg Arg Ala Glu Asp Gly Ser Val Ile Asp Tyr Glu Leu Ile Asp Gln 
            180                 185                 190         


Asp Ala Arg Asp Leu Tyr Asp Ala Gly Val Lys Arg Lys Gly Thr Asp 
        195                 200                 205             


Val Pro Lys Trp Ile Ser Ile Met Thr Glu Arg Ser Val Pro His Leu 
    210                 215                 220                 


Gln Lys Val Phe Asp Arg Tyr Lys Ser Tyr Ser Pro Tyr Asp Met Leu 
225                 230                 235                 240 


Glu Ser Ile Arg Lys Glu Val Lys Gly Asp Leu Glu Asn Ala Phe Leu 
                245                 250                 255     


Asn Leu Val Gln Cys Ile Gln Asn Lys Pro Leu Tyr Phe Ala Asp Arg 
            260                 265                 270         


Leu Tyr Asp Ser Met Lys Gly Lys Gly Thr Arg Asp Lys Val Leu Ile 
        275                 280                 285             


Arg Ile Met Val Ser Arg Ser Glu Val Asp Met Leu Lys Ile Arg Ser 
    290                 295                 300                 


Glu Phe Lys Arg Lys Tyr Gly Lys Ser Leu Tyr Tyr Tyr Ile Gln Gln 
305                 310                 315                 320 


Asp Thr Lys Gly Asp Tyr Gln Lys Ala Leu Leu Tyr Leu Cys Gly Gly 
                325                 330                 335     


Asp Asp 
        


<210>  2013
<211>  182
<212>  PRT
<213>  Homo Sapiens

<400>  2013

Gln Lys Pro Gln Arg Pro Arg Arg Pro Ala Ser Pro Ile Ser Thr Ile 
1               5                   10                  15      


Gln Pro Lys Ala Asn Phe Asp Ala Gln Gln Phe Ala Gly Thr Trp Leu 
            20                  25                  30          


Leu Val Ala Val Gly Ser Ala Cys Arg Phe Leu Gln Glu Gln Gly His 
        35                  40                  45              


Arg Ala Glu Ala Thr Thr Leu His Val Ala Pro Gln Gly Thr Ala Met 
    50                  55                  60                  


Ala Val Ser Thr Phe Arg Lys Leu Asp Gly Ile Cys Trp Gln Val Arg 
65                  70                  75                  80  


Gln Leu Tyr Gly Asp Thr Gly Val Leu Gly Arg Phe Leu Leu Gln Ala 
                85                  90                  95      


Arg Gly Ala Arg Gly Ala Val His Val Val Val Ala Glu Thr Asp Tyr 
            100                 105                 110         


Gln Ser Phe Ala Val Leu Tyr Leu Glu Arg Ala Gly Gln Leu Ser Val 
        115                 120                 125             


Lys Leu Tyr Ala Arg Ser Leu Pro Val Ser Asp Ser Val Leu Ser Gly 
    130                 135                 140                 


Phe Glu Gln Arg Val Gln Glu Ala His Leu Thr Glu Asp Gln Ile Phe 
145                 150                 155                 160 


Tyr Phe Pro Lys Tyr Gly Phe Cys Glu Ala Ala Asp Gln Phe His Val 
                165                 170                 175     


Leu Asp Glu Val Arg Arg 
            180         


<210>  2014
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2014

Ile Val Gly Gly Tyr Asn Cys Glu Glu Asn Ser Val Pro Tyr Gln Val 
1               5                   10                  15      


Ser Leu Asn Ser Gly Tyr His Phe Cys Gly Gly Ser Leu Ile Asn Glu 
            20                  25                  30          


Gln Trp Val Val Ser Ala Gly His Cys Tyr Lys Ser Arg Ile Gln Val 
        35                  40                  45              


Arg Leu Gly Glu His Asn Ile Glu Val Leu Glu Gly Asn Glu Gln Phe 
    50                  55                  60                  


Ile Asn Ala Ala Lys Ile Ile Arg His Pro Gln Tyr Asp Arg Lys Thr 
65                  70                  75                  80  


Leu Asn Asn Asp Ile Met Leu Ile Lys Leu Ser Ser Arg Ala Val Ile 
                85                  90                  95      


Asn Ala Arg Val Ser Thr Ile Ser Leu Pro Thr Ala Pro Pro Ala Thr 
            100                 105                 110         


Gly Thr Lys Cys Leu Ile Ser Gly Trp Gly Asn Thr Ala Ser Ser Gly 
        115                 120                 125             


Ala Asp Tyr Pro Asp Glu Leu Gln Cys Leu Asp Ala Pro Val Leu Ser 
    130                 135                 140                 


Gln Ala Lys Cys Glu Ala Ser Tyr Pro Gly Lys Ile Thr Ser Asn Met 
145                 150                 155                 160 


Phe Cys Val Gly Phe Leu Glu Gly Gly Lys Asp Ser Cys Gln Gly Asp 
                165                 170                 175     


Ser Gly Gly Pro Val Val Cys Asn Gly Gln Leu Gln Gly Val Val Ser 
            180                 185                 190         


Trp Gly Asp Gly Cys Ala Gln Lys Asn Lys Pro Gly Val Tyr Thr Lys 
        195                 200                 205             


Val Tyr Asn Tyr Val Lys Trp Ile Lys Asn Thr Ile Ala Ala Asn Ser 
    210                 215                 220                 


<210>  2015
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2015

Ile Val Gly Gly Tyr Ile Cys Glu Glu Asn Ser Val Pro Tyr Gln Val 
1               5                   10                  15      


Ser Leu Asn Ser Gly Tyr His Phe Cys Gly Gly Ser Leu Ile Ser Glu 
            20                  25                  30          


Gln Trp Val Val Ser Ala Gly His Cys Tyr Lys Ser Arg Ile Gln Val 
        35                  40                  45              


Arg Leu Gly Glu His Asn Ile Glu Val Leu Glu Gly Asn Glu Gln Phe 
    50                  55                  60                  


Ile Asn Ala Ala Lys Ile Ile Arg His Pro Lys Tyr Asn Ser Arg Thr 
65                  70                  75                  80  


Leu Asp Asn Asp Ile Leu Leu Ile Lys Leu Ser Ser Pro Ala Val Ile 
                85                  90                  95      


Asn Ser Arg Val Ser Ala Ile Ser Leu Pro Thr Ala Pro Pro Ala Ala 
            100                 105                 110         


Gly Thr Glu Ser Leu Ile Ser Gly Trp Gly Asn Thr Leu Ser Ser Gly 
        115                 120                 125             


Ala Asp Tyr Pro Asp Glu Leu Gln Cys Leu Asp Ala Pro Val Leu Ser 
    130                 135                 140                 


Gln Ala Glu Cys Glu Ala Ser Tyr Pro Gly Lys Ile Thr Asn Asn Met 
145                 150                 155                 160 


Phe Cys Val Gly Phe Leu Glu Gly Gly Lys Asp Ser Cys Gln Gly Asp 
                165                 170                 175     


Ser Gly Gly Pro Val Val Ser Asn Gly Glu Leu Gln Gly Ile Val Ser 
            180                 185                 190         


Trp Gly Tyr Gly Cys Ala Gln Lys Asn Arg Pro Gly Val Tyr Thr Lys 
        195                 200                 205             


Val Tyr Asn Tyr Val Asp Trp Ile Lys Asp Thr Ile Ala Ala Asn Ser 
    210                 215                 220                 


<210>  2016
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2016

Glu Val Gln Asn Gln Lys Gln Pro Ala Cys His Glu Asn Asp Glu Arg 
1               5                   10                  15      


Pro Phe Tyr Gln Lys Thr Ala Pro Tyr Val Pro Met Tyr Tyr Val Pro 
            20                  25                  30          


Asn Ser Tyr Pro Tyr Tyr Gly Thr Asn Leu Tyr Gln Arg Arg Pro Ala 
        35                  40                  45              


Ile Ala Ile Asn Asn Pro Cys Val Pro Arg Thr Tyr Tyr Ala Asn Pro 
    50                  55                  60                  


Ala Val Val Arg Pro His Ala Gln Ile Pro Gln Arg Gln Tyr Leu Pro 
65                  70                  75                  80  


Asn Ser His Pro Pro Thr Val Val Arg Arg Pro Asn Leu His Pro Ser 
                85                  90                  95      


Phe Ile Ala Ile Pro Pro Lys Lys Ile Gln Asp Lys Ile Ile Ile Pro 
            100                 105                 110         


Thr Ile Asn Thr Ile Ala Thr Val Glu Pro Thr Pro Ala Pro Ala Thr 
        115                 120                 125             


Glu Pro Thr Val Asp Ser Val Val Thr Pro Glu Ala Phe Ser Glu Ser 
    130                 135                 140                 


Ile Ile Thr Ser Thr Pro Glu Thr Thr Thr Val Ala Val Thr Pro Pro 
145                 150                 155                 160 


Thr Ala 
        


<210>  2017
<211>  83
<212>  PRT
<213>  Homo Sapiens

<400>  2017

Ser Leu Pro Cys Asp Ile Cys Lys Asp Val Val Thr Ala Ala Gly Asp 
1               5                   10                  15      


Met Leu Lys Asp Asn Ala Thr Glu Glu Glu Ile Leu Val Tyr Leu Glu 
            20                  25                  30          


Lys Thr Cys Asp Trp Leu Pro Lys Pro Asn Met Ser Ala Ser Cys Lys 
        35                  40                  45              


Glu Ile Val Asp Ser Tyr Leu Pro Val Ile Leu Asp Ile Ile Lys Gly 
    50                  55                  60                  


Glu Met Ser Arg Pro Gly Glu Val Cys Ser Ala Leu Asn Leu Cys Glu 
65                  70                  75                  80  


Ser Leu Gln 
            


<210>  2018
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  2018

Thr Gln Val Gln Gln Leu Leu Val Ser Ile Thr Leu Gln Ser Glu Cys 
1               5                   10                  15      


Asp Ala Phe Pro Asn Ile Ser Ser Asp Glu Ser Tyr Thr Leu Leu Val 
            20                  25                  30          


Lys Glu Pro Val Ala Val Leu Lys Ala Asn Arg Val Trp Gly Ala Leu 
        35                  40                  45              


Arg Gly Leu Glu Thr Phe Ser Gln Leu Val Tyr Gln Asp Ser Tyr Gly 
    50                  55                  60                  


Thr Phe Thr Ile Asn Glu Ser Thr Ile Ile Asp Ser Pro Arg Phe Ser 
65                  70                  75                  80  


His Arg Gly Ile Leu Ile Asp Thr Ser Arg His Tyr Leu Pro Val Lys 
                85                  90                  95      


Ile Ile Leu Lys Thr Leu Asp Ala Met Ala Phe Asn Lys Phe Asn Val 
            100                 105                 110         


Leu His Trp His Ile Val Asp Asp Gln Ser Phe Pro Tyr Gln Ser Ile 
        115                 120                 125             


Thr Phe Pro Glu Leu Ser Asn Lys Gly Ser Tyr Ser Leu Ser His Val 
    130                 135                 140                 


Tyr Thr Pro Asn Asp Val Arg Met Val Ile Glu Tyr Ala Arg Leu Arg 
145                 150                 155                 160 


Gly Ile Arg Val Leu Pro Glu Phe Asp Thr Pro Gly His Thr Leu Ser 
                165                 170                 175     


Trp Gly Lys Gly Gln Lys Asp Leu Leu Thr Pro Cys Tyr Ser Arg Gln 
            180                 185                 190         


Asn Lys Leu Asp Ser Phe Gly Pro Ile Asn Pro Thr Leu Asn Thr Thr 
        195                 200                 205             


Tyr Ser Phe Leu Thr Thr Phe Phe Lys Glu Ile Ser Glu Val Phe Pro 
    210                 215                 220                 


Asp Gln Phe Ile His Leu Gly Gly Asp Glu Val Glu Phe Lys Cys Trp 
225                 230                 235                 240 


Glu Ser Asn Pro Lys Ile Gln Asp Phe Met Arg Gln Lys Gly Phe Gly 
                245                 250                 255     


Thr Asp Phe Lys Lys Leu Glu Ser Phe Tyr Ile Gln Lys Val Leu Asp 
            260                 265                 270         


Ile Ile Ala Thr Ile Asn Lys Gly Ser Ile Val Trp Gln Glu Val Phe 
        275                 280                 285             


Asp Asp Lys Ala Lys Leu Ala Pro Gly Thr Ile Val Glu Val Trp Lys 
    290                 295                 300                 


Asp Ser Ala Tyr Pro Glu Glu Leu Ser Arg Val Thr Ala Ser Gly Phe 
305                 310                 315                 320 


Pro Val Ile Leu Ser Ala Pro Trp Tyr Leu Asp Leu Ile Ser Tyr Gly 
                325                 330                 335     


Gln Asp Trp Arg Lys Tyr Tyr Lys Val Glu Pro Leu Asp Phe Gly Gly 
            340                 345                 350         


Thr Gln Lys Gln Lys Gln Leu Phe Ile Gly Gly Glu Ala Cys Leu Trp 
        355                 360                 365             


Gly Glu Tyr Val Asp Ala Thr Asn Leu Thr Pro Arg Leu Trp Pro Arg 
    370                 375                 380                 


Ala Ser Ala Val Gly Glu Arg Leu Trp Ser Ser Lys Asp Val Arg Asp 
385                 390                 395                 400 


Met Asp Asp Ala Tyr Asp Arg Leu Thr Arg His Arg Cys Arg Met Val 
                405                 410                 415     


Glu Arg Gly Ile Ala Ala Gln Pro Leu Tyr Ala Gly Tyr Cys Asn His 
            420                 425                 430         


Glu Asn Met 
        435 


<210>  2019
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  2019

Ala Pro Arg Ser Val Asp Trp Arg Glu Lys Gly Tyr Val Thr Pro Val 
1               5                   10                  15      


Lys Asn Gln Gly Gln Cys Gly Ser Cys Trp Ala Phe Ser Ala Thr Gly 
            20                  25                  30          


Ala Leu Glu Gly Gln Met Phe Arg Lys Thr Gly Arg Leu Ile Ser Leu 
        35                  40                  45              


Ser Glu Gln Asn Leu Val Asp Cys Ser Gly Pro Gln Gly Asn Glu Gly 
    50                  55                  60                  


Cys Asn Gly Gly Leu Met Asp Tyr Ala Phe Gln Tyr Val Gln Asp Asn 
65                  70                  75                  80  


Gly Gly Leu Asp Ser Glu Glu Ser Tyr Pro Tyr Glu Ala Thr Glu Glu 
                85                  90                  95      


Ser Cys Lys Tyr Asn Pro Lys Tyr Ser Val Ala Asn Asp Thr Gly Phe 
            100                 105                 110         


Val Asp Ile Pro Lys Gln Glu Lys Ala Leu Met Lys Ala Val Ala Thr 
        115                 120                 125             


Val Gly Pro Ile Ser Val Ala Ile Asp Ala Gly His Glu Ser Phe Leu 
    130                 135                 140                 


Phe Tyr Lys Glu Gly Ile Tyr Phe Glu Pro Asp Cys Ser Ser Glu Asp 
145                 150                 155                 160 


Met Asp His Gly Val Leu Val Val Gly Tyr Gly Phe Glu Ser Thr Glu 
                165                 170                 175     


Ser Asp Asn Asn Lys Tyr Trp Leu Val Lys Asn Ser Trp Gly Glu Glu 
            180                 185                 190         


Trp Gly Met Gly Gly Tyr Val Lys Met Ala Lys Asp Arg Arg Asn His 
        195                 200                 205             


Cys Gly Ile Ala Ser Ala Ala Ser Tyr Pro Thr Val 
    210                 215                 220 


<210>  2020
<211>  607
<212>  PRT
<213>  Homo Sapiens

<400>  2020

Leu Tyr Phe Ser Arg Asp Ala Tyr Trp Glu Lys Leu Tyr Val Asp Gln 
1               5                   10                  15      


Ala Ala Gly Thr Pro Leu Leu Tyr Val His Ala Leu Arg Asp Ala Pro 
            20                  25                  30          


Glu Glu Val Pro Ser Phe Arg Leu Gly Gln His Leu Tyr Gly Thr Tyr 
        35                  40                  45              


Arg Thr Arg Leu His Glu Asn Asn Trp Ile Cys Ile Gln Glu Asp Thr 
    50                  55                  60                  


Gly Leu Leu Tyr Leu Asn Arg Ser Leu Asp His Ser Ser Trp Glu Lys 
65                  70                  75                  80  


Leu Ser Val Arg Asn Arg Gly Phe Pro Leu Leu Thr Val Tyr Leu Lys 
                85                  90                  95      


Val Phe Leu Ser Pro Thr Ser Leu Arg Glu Gly Glu Cys Gln Trp Pro 
            100                 105                 110         


Gly Cys Ala Arg Val Tyr Phe Ser Phe Phe Asn Thr Ser Phe Pro Ala 
        115                 120                 125             


Cys Ser Ser Leu Lys Pro Arg Glu Leu Cys Phe Pro Glu Thr Arg Pro 
    130                 135                 140                 


Ser Phe Arg Ile Arg Glu Asn Arg Pro Pro Gly Thr Phe His Gln Phe 
145                 150                 155                 160 


Arg Leu Leu Pro Val Gln Phe Leu Cys Pro Asn Ile Ser Val Ala Tyr 
                165                 170                 175     


Arg Leu Leu Glu Gly Glu Gly Leu Pro Phe Arg Cys Ala Pro Asp Ser 
            180                 185                 190         


Leu Glu Val Ser Thr Arg Trp Ala Leu Asp Arg Glu Gln Arg Glu Lys 
        195                 200                 205             


Tyr Glu Leu Val Ala Val Cys Thr Val His Ala Gly Ala Arg Glu Glu 
    210                 215                 220                 


Val Val Met Val Pro Phe Pro Val Thr Val Tyr Asp Glu Asp Asp Ser 
225                 230                 235                 240 


Ala Pro Thr Phe Pro Ala Gly Val Asp Thr Ala Ser Ala Val Val Glu 
                245                 250                 255     


Phe Lys Arg Lys Glu Asp Thr Val Val Ala Thr Leu Arg Val Phe Asp 
            260                 265                 270         


Ala Asp Val Val Pro Ala Ser Gly Glu Leu Val Arg Arg Tyr Thr Ser 
        275                 280                 285             


Thr Leu Leu Pro Gly Asp Thr Trp Ala Gln Gln Thr Phe Arg Val Glu 
    290                 295                 300                 


His Trp Pro Asn Glu Thr Ser Val Gln Ala Asn Gly Ser Phe Val Arg 
305                 310                 315                 320 


Ala Thr Val His Asp Tyr Arg Leu Val Leu Asn Arg Asn Leu Ser Ile 
                325                 330                 335     


Ser Glu Asn Arg Thr Met Gln Leu Ala Val Leu Val Asn Asp Ser Asp 
            340                 345                 350         


Phe Gln Gly Pro Gly Ala Gly Val Leu Leu Leu His Phe Asn Val Ser 
        355                 360                 365             


Val Leu Pro Val Ser Leu His Leu Pro Ser Thr Tyr Ser Leu Ser Val 
    370                 375                 380                 


Ser Arg Arg Ala Arg Arg Phe Ala Gln Ile Gly Lys Val Cys Val Glu 
385                 390                 395                 400 


Asn Cys Gln Ala Phe Ser Gly Ile Asn Val Gln Tyr Lys Leu His Ser 
                405                 410                 415     


Ser Gly Ala Asn Cys Ser Thr Leu Gly Val Val Thr Ser Ala Glu Asp 
            420                 425                 430         


Thr Ser Gly Ile Leu Phe Val Asn Asp Thr Lys Ala Leu Arg Arg Pro 
        435                 440                 445             


Lys Cys Ala Glu Leu His Tyr Met Val Val Ala Thr Asp Gln Gln Thr 
    450                 455                 460                 


Ser Arg Gln Ala Gln Ala Gln Leu Leu Val Thr Val Glu Gly Ser Tyr 
465                 470                 475                 480 


Val Ala Glu Glu Ala Gly Cys Pro Leu Ser Cys Ala Val Ser Lys Arg 
                485                 490                 495     


Arg Leu Glu Cys Glu Glu Cys Gly Gly Leu Gly Ser Pro Thr Gly Arg 
            500                 505                 510         


Cys Glu Trp Arg Gln Gly Asp Gly Lys Gly Ile Thr Arg Asn Phe Ser 
        515                 520                 525             


Thr Cys Ser Pro Ser Thr Lys Thr Cys Pro Asp Gly His Cys Asp Val 
    530                 535                 540                 


Val Glu Thr Gln Asp Ile Asn Ile Cys Pro Gln Asp Cys Leu Arg Gly 
545                 550                 555                 560 


Ser Ile Val Gly Gly His Glu Pro Gly Glu Pro Arg Gly Ile Lys Ala 
                565                 570                 575     


Gly Tyr Gly Thr Cys Asn Cys Phe Pro Glu Glu Glu Lys Cys Phe Cys 
            580                 585                 590         


Glu Pro Glu Asp Ile Gln Asp Pro Leu Cys Asp Glu Leu Cys Arg 
        595                 600                 605         


<210>  2021
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  2021

Phe Pro Ile Pro Leu Pro Tyr Cys Trp Leu Cys Arg Ala Leu Ile Lys 
1               5                   10                  15      


Arg Ile Gln Ala Met Ile Pro Lys Gly Ala Leu Ala Val Ala Val Ala 
            20                  25                  30          


Gln Val Cys Arg Val Val Pro Leu Val Ala Gly Gly Ile Cys Gln Cys 
        35                  40                  45              


Leu Ala Glu Arg Tyr Ser Val Ile Leu Leu Asp Thr Leu Leu Gly Arg 
    50                  55                  60                  


Met Leu Pro Gln Leu Val Cys Arg Leu Val Leu Arg Cys Ser Met 
65                  70                  75                  


<210>  2022
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  2022

Lys Glu Ser Arg Ala Lys Lys Phe Gln Arg Gln His Met Asp Ser Asp 
1               5                   10                  15      


Ser Ser Pro Ser Ser Ser Ser Thr Tyr Cys Asn Gln Met Met Arg Arg 
            20                  25                  30          


Arg Asn Met Thr Gln Gly Arg Cys Lys Pro Val Asn Thr Phe Val His 
        35                  40                  45              


Glu Pro Leu Val Asp Val Gln Asn Val Cys Phe Gln Glu Lys Val Thr 
    50                  55                  60                  


Cys Lys Asn Gly Gln Gly Asn Cys Tyr Lys Ser Asn Ser Ser Met His 
65                  70                  75                  80  


Ile Thr Asp Cys Arg Leu Thr Asn Gly Ser Arg Tyr Pro Asn Cys Ala 
                85                  90                  95      


Tyr Arg Thr Ser Pro Lys Glu Arg His Ile Ile Val Ala Cys Glu Gly 
            100                 105                 110         


Ser Pro Tyr Val Pro Val His Phe Asp Ala Ser Val Glu Asp Ser Thr 
        115                 120                 125             


<210>  2023
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2023

Ser Cys Tyr Phe Ile Pro Asn Glu Gly Val Pro Gly Asp Ser Thr Arg 
1               5                   10                  15      


Lys Cys Met Asp Leu Lys Gly Asn Lys His Pro Ile Asn Ser Glu Trp 
            20                  25                  30          


Gln Thr Asp Asn Cys Glu Thr Cys Thr Cys Tyr Glu Thr Glu Ile Ser 
        35                  40                  45              


Cys Cys Thr Leu Val Ser Thr Pro Val Gly Tyr Asp Lys Asp Asn Cys 
    50                  55                  60                  


Gln Arg Ile Phe Lys Lys Glu Asp Cys Lys Tyr Ile Val Val Glu Lys 
65                  70                  75                  80  


Lys Asp Pro Lys Lys Thr Cys Ser Val Ser Glu Trp Ile Ile 
                85                  90                  


<210>  2024
<211>  383
<212>  PRT
<213>  Homo Sapiens

<400>  2024

Met Asp Pro Asn Ala Ala Tyr Val Asn Met Ser Asn His His Arg Gly 
1               5                   10                  15      


Leu Ala Ser Ala Asn Val Asp Phe Ala Phe Ser Leu Tyr Lys His Leu 
            20                  25                  30          


Val Ala Leu Ser Pro Lys Lys Asn Ile Phe Ile Ser Pro Val Ser Ile 
        35                  40                  45              


Ser Met Ala Leu Ala Met Leu Ser Leu Gly Thr Cys Gly His Thr Arg 
    50                  55                  60                  


Ala Gln Leu Leu Gln Gly Leu Gly Phe Asn Leu Thr Glu Arg Ser Glu 
65                  70                  75                  80  


Thr Glu Ile His Gln Gly Phe Gln His Leu His Gln Leu Phe Ala Lys 
                85                  90                  95      


Ser Asp Thr Ser Leu Glu Met Thr Met Gly Asn Ala Leu Phe Leu Asp 
            100                 105                 110         


Gly Ser Leu Glu Leu Leu Glu Ser Phe Ser Ala Asp Ile Lys His Tyr 
        115                 120                 125             


Tyr Glu Ser Glu Val Leu Ala Met Asn Phe Gln Asp Trp Ala Thr Ala 
    130                 135                 140                 


Ser Arg Gln Ile Asn Ser Tyr Val Lys Asn Lys Thr Gln Gly Lys Ile 
145                 150                 155                 160 


Val Asp Leu Phe Ser Gly Leu Asp Ser Pro Ala Ile Leu Val Leu Val 
                165                 170                 175     


Asn Tyr Ile Phe Phe Lys Gly Thr Trp Thr Gln Pro Phe Asp Leu Ala 
            180                 185                 190         


Ser Thr Arg Glu Glu Asn Phe Tyr Val Asp Glu Thr Thr Val Val Lys 
        195                 200                 205             


Val Pro Met Met Leu Gln Ser Ser Thr Ile Ser Tyr Leu His Asp Ala 
    210                 215                 220                 


Glu Leu Pro Cys Gln Leu Val Gln Met Asn Tyr Val Gly Asn Gly Thr 
225                 230                 235                 240 


Val Phe Phe Ile Leu Pro Asp Lys Gly Lys Met Asn Thr Val Ile Ala 
                245                 250                 255     


Ala Leu Ser Arg Asp Thr Ile Asn Arg Trp Ser Ala Gly Leu Thr Ser 
            260                 265                 270         


Ser Gln Val Asp Leu Tyr Ile Pro Lys Val Thr Ile Ser Gly Val Tyr 
        275                 280                 285             


Asp Leu Gly Asp Val Leu Glu Glu Met Gly Ile Ala Asp Leu Phe Thr 
    290                 295                 300                 


Asn Gln Ala Asn Phe Ser Arg Ile Thr Gln Asp Ala Gln Leu Lys Ser 
305                 310                 315                 320 


Ser Lys Val Val His Lys Ala Val Leu Gln Leu Asn Glu Glu Gly Val 
                325                 330                 335     


Asp Thr Ala Gly Ser Thr Gly Val Thr Leu Asn Leu Thr Ser Lys Pro 
            340                 345                 350         


Ile Ile Leu Arg Phe Asn Gln Pro Phe Ile Ile Met Ile Phe Asp His 
        355                 360                 365             


Phe Thr Trp Ser Ser Leu Phe Leu Ala Arg Val Met Asn Pro Val 
    370                 375                 380             


<210>  2025
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  2025

Val Val Gly Gly Glu Glu Ala Arg Pro Asn Ser Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Gln Tyr Ser Ser Asn Gly Lys Trp Tyr His Thr Cys Gly Gly 
            20                  25                  30          


Ser Leu Ile Ala Asn Ser Trp Val Leu Thr Ala Ala His Cys Ile Ser 
        35                  40                  45              


Ser Ser Arg Thr Tyr Arg Val Gly Leu Gly Arg His Asn Leu Tyr Val 
    50                  55                  60                  


Ala Glu Ser Gly Ser Leu Ala Val Ser Val Ser Lys Ile Val Val His 
65                  70                  75                  80  


Lys Asp Trp Asn Ser Asn Gln Ile Ser Lys Gly Asn Asp Ile Ala Leu 
                85                  90                  95      


Leu Lys Leu Ala Asn Pro Val Ser Leu Thr Asp Lys Ile Gln Leu Ala 
            100                 105                 110         


Cys Leu Pro Pro Ala Gly Thr Ile Leu Pro Asn Asn Tyr Pro Cys Tyr 
        115                 120                 125             


Val Thr Gly Trp Gly Arg Leu Gln Thr Asn Gly Ala Val Pro Asp Val 
    130                 135                 140                 


Leu Gln Gln Gly Arg Leu Leu Val Val Asp Tyr Ala Thr Cys Ser Ser 
145                 150                 155                 160 


Ser Ala Trp Trp Gly Ser Ser Val Lys Thr Ser Met Ile Cys Ala Gly 
                165                 170                 175     


Gly Asp Gly Val Ile Ser Ser Cys Asn Gly Asp Ser Gly Gly Pro Leu 
            180                 185                 190         


Asn Cys Gln Ala Ser Asp Gly Arg Trp Gln Val His Gly Ile Val Ser 
        195                 200                 205             


Phe Gly Ser Arg Leu Gly Cys Asn Tyr Tyr His Lys Pro Ser Val Phe 
    210                 215                 220                 


Thr Arg Val Ser Asn Tyr Ile Asp Trp Ile Asn Ser Val Ile Ala Asn 
225                 230                 235                 240 


Asn 
    


<210>  2026
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  2026

Met Leu Gly Gly Glu Glu Ala Arg Pro Asn Ser Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Gln Tyr Ser Ser Asn Gly Gln Trp Tyr His Thr Cys Gly Gly 
            20                  25                  30          


Ser Leu Ile Ala Asn Ser Trp Val Leu Thr Ala Ala His Cys Ile Ser 
        35                  40                  45              


Ser Ser Gly Ile Tyr Arg Val Met Leu Gly Gln His Asn Leu Tyr Val 
    50                  55                  60                  


Ala Glu Ser Gly Ser Leu Ala Val Ser Val Ser Lys Ile Val Val His 
65                  70                  75                  80  


Lys Asp Trp Asn Ser Asp Gln Val Ser Lys Gly Asn Asp Ile Ala Leu 
                85                  90                  95      


Leu Lys Leu Ala Asn Pro Val Ser Leu Thr Asp Lys Ile Gln Leu Ala 
            100                 105                 110         


Cys Leu Pro Pro Ala Gly Thr Ile Leu Pro Asn Asn Tyr Pro Cys Tyr 
        115                 120                 125             


Val Thr Gly Trp Gly Arg Leu Gln Thr Asn Gly Ala Leu Pro Asp Asp 
    130                 135                 140                 


Leu Lys Gln Gly Arg Leu Leu Val Val Asp Tyr Ala Thr Cys Ser Ser 
145                 150                 155                 160 


Ser Gly Trp Trp Gly Ser Thr Val Lys Thr Asn Met Ile Cys Ala Gly 
                165                 170                 175     


Gly Asp Gly Val Ile Cys Thr Cys Asn Gly Asp Ser Gly Gly Pro Leu 
            180                 185                 190         


Asn Cys Gln Ala Ser Asp Gly Arg Trp Glu Val His Gly Ile Gly Ser 
        195                 200                 205             


Leu Thr Ser Val Leu Gly Cys Asn Tyr Tyr Tyr Lys Pro Ser Ile Phe 
    210                 215                 220                 


Thr Arg Val Ser Asn Tyr Asn Asp Trp Ile Asn Ser Val Ile Ala Asn 
225                 230                 235                 240 


Asn 
    


<210>  2027
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  2027

Ile Val Gly Gly Arg Arg Ala Arg Pro His Ala Trp Pro Phe Met Val 
1               5                   10                  15      


Ser Leu Gln Leu Arg Gly Gly His Phe Cys Gly Ala Thr Leu Ile Ala 
            20                  25                  30          


Pro Asn Phe Val Met Ser Ala Ala His Cys Val Ala Asn Val Asn Val 
        35                  40                  45              


Arg Ala Val Arg Val Val Leu Gly Ala His Asn Leu Ser Arg Arg Glu 
    50                  55                  60                  


Pro Thr Arg Gln Val Phe Ala Val Gln Arg Ile Phe Glu Asn Gly Tyr 
65                  70                  75                  80  


Asp Pro Val Asn Leu Leu Asn Asp Ile Val Ile Leu Gln Leu Asn Gly 
                85                  90                  95      


Ser Ala Thr Ile Asn Ala Asn Val Gln Val Ala Gln Leu Pro Ala Gln 
            100                 105                 110         


Gly Arg Arg Leu Gly Asn Gly Val Gln Cys Leu Ala Met Gly Trp Gly 
        115                 120                 125             


Leu Leu Gly Arg Asn Arg Gly Ile Ala Ser Val Leu Gln Glu Leu Asn 
    130                 135                 140                 


Val Thr Val Val Thr Ser Leu Cys Arg Arg Ser Asn Val Cys Thr Leu 
145                 150                 155                 160 


Val Arg Gly Arg Gln Ala Gly Val Cys Phe Gly Asp Ser Gly Ser Pro 
                165                 170                 175     


Leu Val Cys Asn Gly Leu Ile His Gly Ile Ala Ser Phe Val Arg Gly 
            180                 185                 190         


Gly Cys Ala Ser Gly Leu Tyr Pro Asp Ala Phe Ala Pro Val Ala Gln 
        195                 200                 205             


Phe Val Asn Trp Ile Asp Ser Ile Ile Gln Arg Ser Glu Asp Asn Pro 
    210                 215                 220                 


Cys Pro His Pro Arg Asp Pro Asp Pro Ala Ser Arg Thr His 
225                 230                 235             


<210>  2028
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2028

Phe Arg Thr Phe Pro Gly Ile Pro Lys Trp Arg Lys Thr His Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Val Asn Tyr Thr Pro Asp Leu Pro Lys Asp Ala Val Asp 
            20                  25                  30          


Ser Ala Val Glu Lys Ala Leu Lys Val Trp Glu Glu Val Thr Pro Leu 
        35                  40                  45              


Thr Phe Ser Arg Leu Tyr Glu Gly Glu Ala Asp Ile Met Ile Ser Phe 
    50                  55                  60                  


Ala Val Arg Glu His Gly Asp Phe Tyr Pro Phe Asp Gly Pro Gly Asn 
65                  70                  75                  80  


Val Leu Ala His Ala Tyr Ala Pro Gly Pro Gly Ile Asn Gly Asp Ala 
                85                  90                  95      


His Phe Asp Asp Asp Glu Gln Trp Thr Lys Asp Thr Thr Gly Thr Asn 
            100                 105                 110         


Leu Phe Leu Val Ala Ala His Glu Ile Gly His Ser Leu Gly Leu Phe 
        115                 120                 125             


His Ser Ala Asn Thr Glu Ala Leu Met Tyr Pro Leu Tyr His Ser Leu 
    130                 135                 140                 


Thr Asp Leu Thr Arg Phe Arg Leu Ser Gln Asp Asp Ile Asn Gly Ile 
145                 150                 155                 160 


Gln Ser Leu Tyr Gly Pro Pro Pro Asp Ser Pro Glu Thr Pro Leu Val 
                165                 170                 175     


Pro Thr Glu Pro Val Pro Pro Glu Pro Gly Thr Pro Ala Asn Cys Asp 
            180                 185                 190         


Pro Ala Leu Ser Phe Asp Ala Val Ser Thr Leu Arg Gly Glu Ile Leu 
        195                 200                 205             


Ile Phe Lys Asp Arg His Phe Trp Arg Lys Ser Leu Arg Lys Leu Glu 
    210                 215                 220                 


Pro Glu Leu His Leu Ile Ser Ser Phe Trp Pro Ser Leu Pro Ser Gly 
225                 230                 235                 240 


Val Asp Ala Ala Tyr Glu Val Thr Ser Lys Asp Leu Val Phe Ile Phe 
                245                 250                 255     


Lys Gly Asn Gln Phe Trp Ala Ile Arg Gly Asn Glu Val Arg Ala Gly 
            260                 265                 270         


Tyr Pro Arg Gly Ile His Thr Leu Gly Phe Pro Pro Thr Val Arg Lys 
        275                 280                 285             


Ile Asp Ala Ala Ile Ser Asp Lys Glu Lys Asn Lys Thr Tyr Phe Phe 
    290                 295                 300                 


Val Glu Asp Lys Tyr Trp Arg Phe Asp Glu Lys Arg Asn Ser Met Glu 
305                 310                 315                 320 


Pro Gly Phe Pro Lys Gln Ile Ala Glu Asp Phe Pro Gly Ile Asp Ser 
                325                 330                 335     


Lys Ile Asp Ala Val Phe Glu Glu Phe Gly Phe Phe Tyr Phe Phe Thr 
            340                 345                 350         


Gly Ser Ser Gln Leu Glu Phe Asp Pro Asn Ala Lys Lys Val Thr His 
        355                 360                 365             


Thr Leu Lys Ser Asn Ser Trp Leu Asn Cys 
    370                 375             


<210>  2029
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  2029

Trp Thr Gly Glu Asp Ser Ala Glu Pro Asn Ser Asp Ser Ala Glu Trp 
1               5                   10                  15      


Ile Arg Asp Met Tyr Ala Lys Val Thr Glu Ile Trp Gln Glu Val Met 
            20                  25                  30          


Gln Arg Arg Asp Asp Asp Gly Thr Leu His Ala Ala Cys Gln Val Gln 
        35                  40                  45              


Pro Ser Ala Thr Leu Asp Ala Ala Gln Pro Arg Val Thr Gly Val Val 
    50                  55                  60                  


Leu Phe Arg Gln Leu Ala Pro Arg Ala Lys Leu Asp Ala Phe Phe Ala 
65                  70                  75                  80  


Leu Glu Gly Phe Pro Thr Glu Pro Asn Ser Ser Ser Arg Ala Ile His 
                85                  90                  95      


Val His Gln Phe Gly Asp Leu Ser Gln Gly Cys Glu Ser Thr Gly Pro 
            100                 105                 110         


His Tyr Asn Pro Leu Ala Val Pro His Pro Gln His Pro Gly Asp Phe 
        115                 120                 125             


Gly Asn Phe Ala Val Arg Asp Gly Ser Leu Trp Arg Tyr Arg Ala Gly 
    130                 135                 140                 


Leu Ala Ala Ser Leu Ala Gly Pro His Ser Ile Val Gly Arg Ala Val 
145                 150                 155                 160 


Val Val His Ala Gly Glu Asp Asp Leu Gly Arg Gly Gly Asn Gln Ala 
                165                 170                 175     


Ser Val Glu Asn Gly Asn Ala Gly Arg Arg Leu Ala Cys Cys Val Val 
            180                 185                 190         


Gly Val Cys Gly Pro Gly Leu Trp Glu Arg Gln Ala Arg Glu His Ser 
        195                 200                 205             


Glu Arg Lys Lys Arg Arg Arg Glu Ser Glu Cys Lys Ala Ala 
    210                 215                 220         


<210>  2030
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  2030

Ile Ile Gly Gly Arg Glu Ser Arg Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Tyr Leu Gln Ile Gln Ser Pro Ala Gly Gln Ser Arg Cys Gly Gly Phe 
            20                  25                  30          


Leu Val Arg Glu Asp Phe Val Leu Thr Ala Ala His Cys Trp Gly Ser 
        35                  40                  45              


Asn Ile Asn Val Thr Leu Gly Ala His Asn Ile Gln Arg Arg Glu Asn 
    50                  55                  60                  


Thr Gln Gln His Ile Thr Ala Arg Arg Ala Ile Arg His Pro Gln Tyr 
65                  70                  75                  80  


Asn Gln Arg Thr Ile Gln Asn Asp Ile Met Leu Leu Gln Leu Ser Arg 
                85                  90                  95      


Arg Val Arg Arg Asn Arg Asn Val Asn Pro Val Ala Leu Pro Arg Ala 
            100                 105                 110         


Gln Glu Gly Leu Arg Pro Gly Thr Leu Cys Thr Val Ala Gly Trp Gly 
        115                 120                 125             


Arg Val Ser Met Arg Arg Gly Thr Asp Thr Leu Arg Glu Val Gln Leu 
    130                 135                 140                 


Arg Val Gln Arg Asp Arg Gln Cys Leu Arg Ile Phe Gly Ser Tyr Asp 
145                 150                 155                 160 


Pro Arg Arg Gln Ile Cys Val Gly Asp Arg Arg Glu Arg Lys Ala Ala 
                165                 170                 175     


Phe Lys Gly Asp Ser Gly Gly Pro Leu Leu Cys Asn Asn Val Ala His 
            180                 185                 190         


Gly Ile Val Ser Tyr Gly Lys Ser Ser Gly Val Pro Pro Glu Val Phe 
        195                 200                 205             


Thr Arg Val Ser Ser Phe Leu Pro Trp Ile Arg Thr Thr Met Arg Ser 
    210                 215                 220                 


Phe Lys Leu Leu Asp Gln Met Glu Thr Pro Leu 
225                 230                 235 


<210>  2031
<211>  699
<212>  PRT
<213>  Homo Sapiens

<400>  2031

Tyr Asp Asp Gly Ile Cys Lys Ser Ser Asp Cys Ile Lys Ser Ala Ala 
1               5                   10                  15      


Arg Leu Ile Gln Asn Met Asp Ala Thr Thr Glu Pro Cys Thr Asp Phe 
            20                  25                  30          


Phe Lys Tyr Ala Cys Gly Gly Trp Leu Lys Arg Asn Val Ile Pro Glu 
        35                  40                  45              


Thr Ser Ser Arg Tyr Gly Asn Phe Asp Ile Leu Arg Asp Glu Leu Glu 
    50                  55                  60                  


Val Val Leu Lys Asp Val Leu Gln Glu Pro Lys Thr Glu Asp Ile Val 
65                  70                  75                  80  


Ala Val Gln Lys Ala Lys Ala Leu Tyr Arg Ser Cys Ile Asn Glu Ser 
                85                  90                  95      


Ala Ile Asp Ser Arg Gly Gly Glu Pro Leu Leu Lys Leu Leu Pro Asp 
            100                 105                 110         


Ile Tyr Gly Trp Pro Val Ala Thr Glu Asn Trp Glu Gln Lys Tyr Gly 
        115                 120                 125             


Ala Ser Trp Thr Ala Glu Lys Ala Ile Ala Gln Leu Asn Ser Lys Tyr 
    130                 135                 140                 


Gly Lys Lys Val Leu Ile Asn Leu Phe Val Gly Thr Asp Asp Lys Asn 
145                 150                 155                 160 


Ser Val Asn His Val Ile His Ile Asp Gln Pro Arg Leu Gly Leu Pro 
                165                 170                 175     


Ser Arg Asp Tyr Tyr Glu Cys Thr Gly Ile Tyr Lys Glu Ala Cys Thr 
            180                 185                 190         


Ala Tyr Val Asp Phe Met Ile Ser Val Ala Arg Leu Ile Arg Gln Glu 
        195                 200                 205             


Glu Arg Leu Pro Ile Asp Glu Asn Gln Leu Ala Leu Glu Met Asn Lys 
    210                 215                 220                 


Val Met Glu Leu Glu Lys Glu Ile Ala Asn Ala Thr Ala Lys Pro Glu 
225                 230                 235                 240 


Asp Arg Asn Asp Pro Met Leu Leu Tyr Asn Lys Met Thr Leu Ala Gln 
                245                 250                 255     


Ile Gln Asn Asn Phe Ser Leu Glu Ile Asn Gly Lys Pro Phe Ser Trp 
            260                 265                 270         


Leu Asn Phe Thr Asn Glu Ile Met Ser Thr Val Asn Ile Ser Ile Thr 
        275                 280                 285             


Asn Glu Glu Asp Val Val Val Tyr Ala Pro Glu Tyr Leu Thr Lys Leu 
    290                 295                 300                 


Lys Pro Ile Leu Thr Lys Tyr Ser Ala Arg Asp Leu Gln Asn Leu Met 
305                 310                 315                 320 


Ser Trp Arg Phe Ile Met Asp Leu Val Ser Ser Leu Ser Arg Thr Tyr 
                325                 330                 335     


Lys Glu Ser Arg Asn Ala Phe Arg Lys Ala Leu Tyr Gly Thr Thr Ser 
            340                 345                 350         


Glu Thr Ala Thr Trp Arg Arg Cys Ala Asn Tyr Val Asn Gly Asn Met 
        355                 360                 365             


Glu Asn Ala Val Gly Arg Leu Tyr Val Glu Ala Ala Phe Ala Gly Glu 
    370                 375                 380                 


Ser Lys His Val Val Glu Asp Leu Ile Ala Gln Ile Arg Glu Val Phe 
385                 390                 395                 400 


Ile Gln Thr Leu Asp Asp Leu Thr Trp Met Asp Ala Glu Thr Lys Lys 
                405                 410                 415     


Arg Ala Glu Glu Lys Ala Leu Ala Ile Lys Glu Arg Ile Gly Tyr Pro 
            420                 425                 430         


Asp Asp Ile Val Ser Asn Asp Asn Lys Leu Asn Asn Glu Tyr Leu Glu 
        435                 440                 445             


Leu Asn Tyr Lys Glu Asp Glu Tyr Phe Glu Asn Ile Ile Gln Asn Leu 
    450                 455                 460                 


Lys Phe Ser Gln Ser Lys Gln Leu Lys Lys Leu Arg Glu Lys Val Asp 
465                 470                 475                 480 


Lys Asp Glu Trp Ile Ser Gly Ala Ala Val Val Asn Ala Phe Tyr Ser 
                485                 490                 495     


Ser Gly Arg Asn Gln Ile Val Phe Pro Ala Gly Ile Leu Gln Pro Pro 
            500                 505                 510         


Phe Phe Ser Ala Gln Gln Ser Asn Ser Leu Asn Tyr Gly Gly Ile Gly 
        515                 520                 525             


Met Val Ile Gly His Glu Ile Thr His Gly Phe Asp Asp Asn Gly Arg 
    530                 535                 540                 


Asn Phe Asn Lys Asp Gly Asp Leu Val Asp Trp Trp Thr Gln Gln Ser 
545                 550                 555                 560 


Ala Ser Asn Phe Lys Glu Gln Ser Gln Cys Met Val Tyr Gln Tyr Gly 
                565                 570                 575     


Asn Phe Ser Trp Asp Leu Ala Gly Gly Gln His Leu Asn Gly Ile Asn 
            580                 585                 590         


Thr Leu Gly Glu Asn Ile Ala Asp Asn Gly Gly Leu Gly Gln Ala Tyr 
        595                 600                 605             


Arg Ala Tyr Gln Asn Tyr Ile Lys Lys Asn Gly Glu Glu Lys Leu Leu 
    610                 615                 620                 


Pro Gly Leu Asp Leu Asn His Lys Gln Leu Phe Phe Leu Asn Phe Ala 
625                 630                 635                 640 


Gln Val Trp Cys Gly Thr Tyr Arg Pro Glu Tyr Ala Val Asn Ser Ile 
                645                 650                 655     


Lys Thr Asp Val His Ser Pro Gly Asn Phe Arg Ile Ile Gly Thr Leu 
            660                 665                 670         


Gln Asn Ser Ala Glu Phe Ser Glu Ala Phe His Cys Arg Lys Asn Ser 
        675                 680                 685             


Tyr Met Asn Pro Glu Lys Lys Cys Arg Val Trp 
    690                 695                 


<210>  2032
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  2032

Gly Leu Glu Cys Asp Gly Lys Val Asn Ile Cys Cys Lys Lys Gln Phe 
1               5                   10                  15      


Phe Val Ser Phe Lys Asp Ile Gly Trp Asn Asp Trp Ile Ile Ala Pro 
            20                  25                  30          


Ser Gly Tyr His Ala Asn Tyr Cys Glu Gly Glu Cys Pro Ser His Ile 
        35                  40                  45              


Ala Gly Thr Ser Gly Ser Ser Leu Ser Phe His Ser Thr Val Ile Asn 
    50                  55                  60                  


His Tyr Arg Met Arg Gly His Ser Pro Phe Ala Asn Leu Lys Ser Cys 
65                  70                  75                  80  


Cys Val Pro Thr Lys Leu Arg Pro Met Ser Met Leu Tyr Tyr Asp Asp 
                85                  90                  95      


Gly Gln Asn Ile Ile Lys Lys Asp Ile Gln Asn Met Ile Val Glu Glu 
            100                 105                 110         


Cys Gly Cys Ser 
        115     


<210>  2033
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2033

Gly Tyr Leu Leu Val Lys His Ser Gln Thr Asp Gln Glu Pro Met Cys 
1               5                   10                  15      


Pro Val Gly Met Asn Lys Leu Trp Ser Gly Tyr Ser Leu Leu Tyr Phe 
            20                  25                  30          


Glu Gly Gln Glu Lys Ala His Asn Gln Asp Leu Gly Leu Ala Gly Ser 
        35                  40                  45              


Cys Leu Ala Arg Phe Ser Thr Met Pro Phe Leu Tyr Cys Asn Pro Gly 
    50                  55                  60                  


Asp Val Cys Tyr Tyr Ala Ser Arg Asn Asp Lys Ser Tyr Trp Leu Ser 
65                  70                  75                  80  


Thr Thr Ala Pro Leu Pro Met Met Pro Val Ala Glu Asp Glu Ile Lys 
                85                  90                  95      


Pro Tyr Ile Ser Arg Cys Ser Val Cys Glu Ala Pro Ala Ile Ala Ile 
            100                 105                 110         


Ala Val His Ser Gln Asp Val Ser Ile Pro His Cys Pro Ala Gly Trp 
        115                 120                 125             


Arg Ser Leu Trp Ile Gly Tyr Ser Phe Leu Met His Thr Ala Ala Gly 
    130                 135                 140                 


Asp Glu Gly Gly Gly Gln Ser Leu Val Ser Pro Gly Ser Cys Leu Glu 
145                 150                 155                 160 


Asp Phe Arg Ala Thr Pro Phe Ile Glu Cys Asn Gly Gly Arg Gly Thr 
                165                 170                 175     


Cys His Tyr Tyr Ala Asn Lys Tyr Ser Phe Trp Leu Thr Thr Ile Pro 
            180                 185                 190         


Glu Gln Ser Phe Gln Gly Ser Pro Ser Ala Asp Thr Leu Lys Ala Gly 
        195                 200                 205             


Leu Ile Arg Thr His Ile Ser Arg Cys Gln Val Cys Met Lys Asn Leu 
    210                 215                 220                 


<210>  2034
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  2034

Asn Gln Glu Gln Val Ser Pro Leu Thr Leu Leu Lys Leu Gly Asn Gln 
1               5                   10                  15      


Glu Pro Gly Gly Gln Thr Ala Leu Lys Ser Pro Pro Gly Val Cys Ser 
            20                  25                  30          


Arg Asp Pro Thr Pro Glu Gln Thr His Arg Leu Ala Arg Ala Met Met 
        35                  40                  45              


Ala Phe Thr Ala Asp Leu Phe Ser Leu Val Ala Gln Thr Ser Thr Cys 
    50                  55                  60                  


Pro Asn Leu Ile Leu Ser Pro Leu Ser Val Ala Leu Ala Leu Ser His 
65                  70                  75                  80  


Leu Ala Leu Gly Ala Gln Asn His Thr Leu Gln Arg Leu Gln Gln Val 
                85                  90                  95      


Leu His Ala Gly Ser Gly Pro Cys Leu Pro His Leu Leu Ser Arg Leu 
            100                 105                 110         


Cys Gln Asp Leu Gly Pro Gly Ala Phe Arg Leu Ala Ala Arg Met Tyr 
        115                 120                 125             


Leu Gln Lys Gly Phe Pro Ile Lys Glu Asp Phe Leu Glu Gln Ser Glu 
    130                 135                 140                 


Gln Leu Phe Gly Ala Lys Pro Val Ser Leu Thr Gly Lys Gln Glu Asp 
145                 150                 155                 160 


Asp Leu Ala Asn Ile Asn Gln Trp Val Lys Glu Ala Thr Glu Gly Lys 
                165                 170                 175     


Ile Gln Glu Phe Leu Ser Gly Leu Pro Glu Asp Thr Val Leu Leu Leu 
            180                 185                 190         


Leu Asn Ala Ile His Phe Gln Gly Phe Trp Arg Asn Lys Phe Asp Pro 
        195                 200                 205             


Ser Leu Thr Gln Arg Asp Ser Phe His Leu Asp Glu Gln Phe Thr Val 
    210                 215                 220                 


Pro Val Glu Met Met Gln Ala Arg Thr Tyr Pro Leu Arg Trp Phe Leu 
225                 230                 235                 240 


Leu Glu Gln Pro Glu Ile Gln Val Ala His Phe Pro Phe Lys Asn Asn 
                245                 250                 255     


Met Ser Phe Val Val Leu Val Pro Thr His Phe Glu Trp Asn Val Ser 
            260                 265                 270         


Gln Val Leu Ala Asn Leu Ser Trp Asp Thr Leu His Pro Pro Leu Val 
        275                 280                 285             


Trp Glu Arg Pro Thr Lys Val Arg Leu Pro Lys Leu Tyr Leu Lys His 
    290                 295                 300                 


Gln Met Asp Leu Val Ala Thr Leu Ser Gln Leu Gly Leu Gln Glu Leu 
305                 310                 315                 320 


Phe Gln Ala Pro Asp Leu Arg Gly Ile Ser Glu Gln Ser Leu Val Val 
                325                 330                 335     


Ser Gly Val Gln His Gln Ser Thr Leu Glu Leu Ser Glu Val Gly Val 
            340                 345                 350         


Glu Ala Ala Ala Ala Thr Ser Ile Ala Met Ser Arg Met Ser Leu Ser 
        355                 360                 365             


Ser Phe Ser Val Asn Arg Pro Phe Leu Phe Phe Ile Phe Glu Asp Thr 
    370                 375                 380                 


Thr Gly Leu Pro Leu Phe Val Gly Ser Val Arg Asn Pro Asn Pro Ser 
385                 390                 395                 400 


Ala Pro Arg Glu Leu Lys Glu Gln Gln Asp Ser Pro Gly Asn Lys Asp 
                405                 410                 415     


Phe Leu Gln Ser Leu Lys Gly Phe Pro Arg Gly Asp Lys Leu Phe Gly 
            420                 425                 430         


Pro Asp Leu Lys Leu Val Pro Pro Met Glu Glu Asp Tyr Pro Gln Phe 
        435                 440                 445             


Gly Ser Pro Lys 
    450         


<210>  2035
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2035

Ala Pro Trp Gln Cys Ala Pro Cys Ser Ala Glu Lys Leu Ala Leu Cys 
1               5                   10                  15      


Pro Pro Val Ser Ala Ser Cys Ser Glu Val Thr Arg Ser Ala Gly Cys 
            20                  25                  30          


Gly Cys Cys Pro Met Cys Ala Leu Pro Leu Gly Ala Ala Cys Gly Val 
        35                  40                  45              


Ala Thr Ala Arg Cys Ala Arg Gly Leu Ser Cys Arg Ala Leu Pro Gly 
    50                  55                  60                  


Glu Gln Gln Pro Leu His Ala Leu Thr Arg Gly Gln Gly Ala Cys Val 
65                  70                  75                  80  


Gln Glu Ser Asp Ala Ser Ala Pro His Ala Ala Glu Ala Gly Ser Pro 
                85                  90                  95      


Glu Ser Pro Glu Ser Thr Glu Ile Thr Glu Glu Glu Leu Leu Asp Asn 
            100                 105                 110         


Phe His Leu Met Ala Pro Ser Glu Glu Asp His Ser Ile Leu Trp Asp 
        115                 120                 125             


Ala Ile Ser Thr Tyr Asp Gly Ser Lys Ala Leu His Val Thr Asn Ile 
    130                 135                 140                 


Lys Lys Trp Lys Glu Pro Cys Arg Ile Glu Leu Tyr Arg Val Val Glu 
145                 150                 155                 160 


Ser Leu Ala Lys Ala Gln Glu Thr Ser Gly Glu Glu Ile Ser Lys Phe 
                165                 170                 175     


Tyr Leu Pro Asn Cys Asn Lys Asn Gly Phe Tyr His Ser Arg Gln Cys 
            180                 185                 190         


Glu Thr Ser Met Asp Gly Glu Ala Gly Leu Cys Trp Cys Val Tyr Pro 
        195                 200                 205             


Trp Asn Gly Lys Arg Ile Pro Gly Ser Pro Glu Ile Arg Gly Asp Pro 
    210                 215                 220                 


Asn Cys Gln Ile Tyr Phe Asn Val Gln Asn 
225                 230                 


<210>  2036
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  2036

Val Val Asn Gly Glu Asp Ala Val Pro Tyr Ser Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Gln Tyr Glu Lys Ser Gly Ser Phe Tyr His Thr Cys Gly Gly 
            20                  25                  30          


Ser Leu Ile Ala Pro Asp Trp Val Val Thr Ala Gly His Cys Ile Ser 
        35                  40                  45              


Ser Ser Trp Thr Tyr Gln Val Val Leu Gly Glu Tyr Asp Arg Ala Val 
    50                  55                  60                  


Lys Glu Gly Pro Glu Gln Val Ile Pro Ile Asn Ser Gly Asp Leu Phe 
65                  70                  75                  80  


Val His Pro Leu Trp Asn Arg Ser Cys Val Ala Cys Gly Asn Asp Ile 
                85                  90                  95      


Ala Leu Ile Lys Leu Ser Arg Ser Ala Gln Leu Gly Asp Ala Val Gln 
            100                 105                 110         


Leu Ala Ser Leu Pro Pro Ala Gly Asp Ile Leu Pro Asn Glu Thr Pro 
        115                 120                 125             


Cys Tyr Ile Thr Gly Trp Gly Arg Leu Tyr Thr Asn Gly Pro Leu Pro 
    130                 135                 140                 


Asp Lys Leu Gln Glu Ala Leu Leu Pro Val Val Asp Tyr Glu His Cys 
145                 150                 155                 160 


Ser Arg Trp Asn Trp Trp Gly Ser Ser Val Lys Lys Thr Met Val Cys 
                165                 170                 175     


Ala Gly Gly Asp Ile Arg Ser Gly Cys Asn Gly Asp Ser Gly Gly Pro 
            180                 185                 190         


Leu Asn Cys Pro Thr Glu Asp Gly Gly Trp Gln Val His Gly Val Thr 
        195                 200                 205             


Ser Phe Val Ser Ala Phe Gly Cys Asn Thr Arg Arg Lys Pro Thr Val 
    210                 215                 220                 


Phe Thr Arg Val Ser Ala Phe Ile Asp Trp Ile Glu Glu Thr Ile Ala 
225                 230                 235                 240 


Ser His 
        


<210>  2037
<211>  395
<212>  PRT
<213>  Homo Sapiens

<400>  2037

Arg Cys Leu Asn Leu Lys Ser Pro Thr Ala Pro Pro Asp Leu Tyr Phe 
1               5                   10                  15      


Gln Asp Ser Gly Leu Ser Arg Phe Leu Leu Lys Ser Cys Pro Leu Leu 
            20                  25                  30          


Thr Lys Glu Tyr Ile Pro Pro Leu Ile Trp Gly Lys Ser Gly His Ile 
        35                  40                  45              


Gln Thr Ala Leu Tyr Gly Lys Met Gly Arg Val Arg Ser Pro His Pro 
    50                  55                  60                  


Tyr Gly His Arg Lys Phe Ile Thr Met Ser Asp Gly Ala Thr Ser Thr 
65                  70                  75                  80  


Phe Asp Leu Phe Glu Pro Leu Ala Glu His Cys Val Gly Asp Asp Ile 
                85                  90                  95      


Thr Met Val Ile Cys Pro Gly Ile Ala Asn His Ser Glu Lys Gln Tyr 
            100                 105                 110         


Ile Arg Thr Phe Val Asp Tyr Ala Gln Lys Asn Gly Tyr Arg Cys Ala 
        115                 120                 125             


Val Leu Asn His Leu Gly Ala Leu Pro Asn Ile Glu Leu Thr Ser Pro 
    130                 135                 140                 


Arg Met Phe Thr Tyr Gly Cys Thr Trp Glu Phe Gly Ala Met Val Asn 
145                 150                 155                 160 


Tyr Ile Lys Lys Thr Tyr Pro Leu Thr Gln Leu Val Val Val Gly Phe 
                165                 170                 175     


Ser Leu Gly Gly Asn Ile Val Cys Lys Tyr Leu Gly Glu Thr Gln Ala 
            180                 185                 190         


Asn Gln Glu Lys Val Leu Cys Cys Val Ser Val Cys Gln Gly Tyr Ser 
        195                 200                 205             


Ala Leu Arg Ala Gln Glu Thr Phe Met Gln Trp Asp Gln Cys Gln Arg 
    210                 215                 220                 


Phe Tyr Asn Phe Leu Met Ala Asp Asn Met Lys Lys Ile Ile Leu Ser 
225                 230                 235                 240 


His Arg Gln Ala Leu Phe Gly Asp His Val Lys Lys Pro Gln Ser Leu 
                245                 250                 255     


Glu Asp Thr Asp Leu Ser Arg Leu Tyr Thr Ala Thr Ser Leu Met Gln 
            260                 265                 270         


Ile Asp Asp Asn Val Met Arg Lys Phe His Gly Tyr Asn Ser Leu Lys 
        275                 280                 285             


Glu Tyr Tyr Glu Glu Glu Ser Cys Met Arg Tyr Leu His Arg Ile Tyr 
    290                 295                 300                 


Val Pro Leu Met Leu Val Asn Ala Ala Asp Asp Pro Leu Val His Glu 
305                 310                 315                 320 


Ser Leu Leu Thr Ile Pro Lys Ser Leu Ser Glu Lys Arg Glu Asn Val 
                325                 330                 335     


Met Phe Val Leu Pro Leu His Gly Gly His Leu Gly Phe Phe Glu Gly 
            340                 345                 350         


Ser Val Leu Phe Pro Glu Pro Leu Thr Trp Met Asp Lys Leu Val Val 
        355                 360                 365             


Glu Tyr Ala Asn Ala Ile Cys Gln Trp Glu Arg Asn Lys Leu Gln Cys 
    370                 375                 380                 


Ser Asp Thr Glu Gln Val Glu Ala Asp Leu Glu 
385                 390                 395 


<210>  2038
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  2038

Val Val His Gly Glu Asp Ala Val Pro Tyr Ser Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Gln Tyr Glu Lys Ser Gly Ser Phe Tyr His Thr Cys Gly Gly 
            20                  25                  30          


Ser Leu Ile Ala Pro Asp Trp Val Val Thr Ala Gly His Cys Ile Ser 
        35                  40                  45              


Arg Asp Leu Thr Tyr Gln Val Val Leu Gly Glu Tyr Asn Leu Ala Val 
    50                  55                  60                  


Lys Glu Gly Pro Glu Gln Val Ile Pro Ile Asn Ser Glu Glu Leu Phe 
65                  70                  75                  80  


Val His Pro Leu Trp Asn Arg Ser Cys Val Ala Cys Gly Asn Asp Ile 
                85                  90                  95      


Ala Leu Ile Lys Leu Ser Arg Ser Ala Gln Leu Gly Asp Ala Val Gln 
            100                 105                 110         


Leu Ala Ser Leu Pro Pro Ala Gly Asp Ile Leu Pro Asn Lys Thr Pro 
        115                 120                 125             


Cys Tyr Ile Thr Gly Trp Gly Arg Leu Tyr Thr Asn Gly Pro Leu Pro 
    130                 135                 140                 


Asp Lys Leu Gln Gln Ala Arg Leu Pro Val Val Asp Tyr Lys His Cys 
145                 150                 155                 160 


Ser Arg Trp Asn Trp Trp Gly Ser Thr Val Lys Lys Thr Met Val Cys 
                165                 170                 175     


Ala Gly Gly Tyr Ile Arg Ser Gly Cys Asn Gly Asp Ser Gly Gly Pro 
            180                 185                 190         


Leu Asn Cys Pro Thr Glu Asp Gly Gly Trp Gln Val His Gly Val Thr 
        195                 200                 205             


Ser Phe Val Ser Gly Phe Gly Cys Asn Phe Ile Trp Lys Pro Thr Val 
    210                 215                 220                 


Phe Thr Arg Val Ser Ala Phe Ile Asp Trp Ile Glu Glu Thr Ile Ala 
225                 230                 235                 240 


Ser His 
        


<210>  2039
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  2039

Trp Ser Pro Gln Glu Glu Asp Arg Ile Ile Glu Gly Gly Ile Tyr Asp 
1               5                   10                  15      


Ala Asp Leu Asn Asp Glu Arg Val Gln Arg Ala Leu His Phe Val Ile 
            20                  25                  30          


Ser Glu Tyr Asn Lys Ala Thr Glu Asp Glu Tyr Tyr Arg Arg Leu Leu 
        35                  40                  45              


Arg Val Leu Arg Ala Arg Glu Gln Ile Val Gly Gly Val Asn Tyr Phe 
    50                  55                  60                  


Phe Asp Ile Glu Val Gly Arg Thr Ile Cys Thr Lys Ser Gln Pro Asn 
65                  70                  75                  80  


Leu Asp Thr Cys Ala Phe His Glu Gln Pro Glu Leu Gln Lys Lys Gln 
                85                  90                  95      


Leu Cys Ser Phe Gln Ile Tyr Glu Val Pro Trp Glu Asp Arg Met Ser 
            100                 105                 110         


Leu Val Asn Ser Arg Cys Gln Glu Ala 
        115                 120     


<210>  2040
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  2040

Tyr Ser Leu Phe Pro Asn Ser Pro Lys Trp Thr Ser Lys Val Val Thr 
1               5                   10                  15      


Tyr Arg Ile Val Ser Tyr Thr Arg Asp Leu Pro His Ile Thr Val Asp 
            20                  25                  30          


Arg Leu Val Ser Lys Ala Leu Asn Met Trp Gly Lys Glu Ile Pro Leu 
        35                  40                  45              


His Phe Arg Lys Val Val Trp Gly Thr Ala Asp Ile Met Ile Gly Phe 
    50                  55                  60                  


Ala Arg Gly Ala His Gly Asp Ser Tyr Pro Phe Asp Gly Pro Gly Asn 
65                  70                  75                  80  


Thr Leu Ala His Ala Phe Ala Pro Gly Thr Gly Leu Gly Gly Asp Ala 
                85                  90                  95      


His Phe Asp Glu Asp Glu Arg Trp Thr Asp Gly Ser Ser Leu Gly Ile 
            100                 105                 110         


Asn Phe Leu Tyr Ala Ala Thr His Glu Leu Gly His Ser Leu Gly Met 
        115                 120                 125             


Gly His Ser Ser Asp Pro Asn Ala Val Met Tyr Pro Thr Tyr Gly Asn 
    130                 135                 140                 


Gly Asp Pro Gln Asn Phe Lys Leu Ser Gln Asp Asp Ile Lys Gly Ile 
145                 150                 155                 160 


Gln Lys Leu Tyr Gly Lys Arg Ser Asn Ser Arg Lys Lys 
                165                 170             


<210>  2041
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2041

Phe Ser Ser Phe Pro Gly Met Pro Lys Trp Arg Lys Thr His Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Val Asn Tyr Thr Pro Asp Leu Pro Arg Asp Ala Val Asp 
            20                  25                  30          


Ser Ala Ile Glu Lys Ala Leu Lys Val Trp Glu Glu Val Thr Pro Leu 
        35                  40                  45              


Thr Phe Ser Arg Leu Tyr Glu Gly Glu Ala Asp Ile Met Ile Ser Phe 
    50                  55                  60                  


Ala Val Lys Glu His Gly Asp Phe Tyr Ser Phe Asp Gly Pro Gly His 
65                  70                  75                  80  


Ser Leu Ala His Ala Tyr Pro Pro Gly Pro Gly Leu Tyr Gly Asp Ile 
                85                  90                  95      


His Phe Asp Asp Asp Glu Lys Trp Thr Glu Asp Ala Ser Gly Thr Asn 
            100                 105                 110         


Leu Phe Leu Val Ala Ala His Glu Leu Gly His Ser Leu Gly Leu Phe 
        115                 120                 125             


His Ser Ala Asn Thr Glu Ala Leu Met Tyr Pro Leu Tyr Asn Ser Phe 
    130                 135                 140                 


Thr Glu Leu Ala Gln Phe Arg Leu Ser Gln Asp Asp Val Asn Gly Ile 
145                 150                 155                 160 


Gln Ser Leu Tyr Gly Pro Pro Pro Ala Ser Thr Glu Glu Pro Leu Val 
                165                 170                 175     


Pro Thr Lys Ser Val Pro Ser Gly Ser Glu Met Pro Ala Lys Cys Asp 
            180                 185                 190         


Pro Ala Leu Ser Phe Asp Ala Ile Ser Thr Leu Arg Gly Glu Tyr Leu 
        195                 200                 205             


Phe Phe Lys Asp Arg Tyr Phe Trp Arg Arg Ser His Trp Asn Pro Glu 
    210                 215                 220                 


Pro Glu Phe His Leu Ile Ser Ala Phe Trp Pro Ser Leu Pro Ser Tyr 
225                 230                 235                 240 


Leu Asp Ala Ala Tyr Glu Val Asn Ser Arg Asp Thr Val Phe Ile Phe 
                245                 250                 255     


Lys Gly Asn Glu Phe Trp Ala Ile Arg Gly Asn Glu Val Gln Ala Gly 
            260                 265                 270         


Tyr Pro Arg Gly Ile His Thr Leu Gly Phe Pro Pro Thr Ile Arg Lys 
        275                 280                 285             


Ile Asp Ala Ala Val Ser Asp Lys Glu Lys Lys Lys Thr Tyr Phe Phe 
    290                 295                 300                 


Ala Ala Asp Lys Tyr Trp Arg Phe Asp Glu Asn Ser Gln Ser Met Glu 
305                 310                 315                 320 


Gln Gly Phe Pro Arg Leu Ile Ala Asp Asp Phe Pro Gly Val Glu Pro 
                325                 330                 335     


Lys Val Asp Ala Val Leu Gln Ala Phe Gly Phe Phe Tyr Phe Phe Ser 
            340                 345                 350         


Gly Ser Ser Gln Phe Glu Phe Asp Pro Asn Ala Arg Met Val Thr His 
        355                 360                 365             


Ile Leu Lys Ser Asn Ser Trp Leu His Cys 
    370                 375             


<210>  2042
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  2042

Ala Cys Gly Leu Val Ala Ser Asn Leu Asn Leu Lys Pro Gly Glu Cys 
1               5                   10                  15      


Leu Arg Val Arg Gly Glu Val Ala Pro Asp Ala Lys Ser Phe Val Leu 
            20                  25                  30          


Asn Leu Gly Lys Asp Ser Asn Asn Leu Cys Leu His Phe Asn Pro Arg 
        35                  40                  45              


Phe Asn Ala His Gly Asp Ala Asn Thr Ile Val Cys Asn Ser Lys Asp 
    50                  55                  60                  


Gly Gly Ala Trp Gly Thr Glu Gln Arg Glu Ala Val Phe Pro Phe Gln 
65                  70                  75                  80  


Pro Gly Ser Val Ala Glu Val Cys Ile Thr Phe Asp Gln Ala Asn Leu 
                85                  90                  95      


Thr Val Lys Leu Pro Asp Gly Tyr Glu Phe Lys Phe Pro Asn Arg Leu 
            100                 105                 110         


Asn Leu Glu Ala Ile Asn Tyr Met Ala Ala Asp Gly Asp Phe Lys Ile 
        115                 120                 125             


Lys Cys Val Ala Phe Asp 
    130                 


<210>  2043
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2043

Met Asp Ile Pro Gln Thr Lys Gln Asp Leu Glu Leu Pro Lys Leu Ala 
1               5                   10                  15      


Gly Thr Trp His Ser Met Ala Met Ala Thr Asn Asn Ile Ser Leu Met 
            20                  25                  30          


Ala Thr Leu Lys Ala Pro Leu Arg Val His Ile Thr Ser Leu Leu Pro 
        35                  40                  45              


Thr Pro Glu Asp Asn Leu Glu Ile Val Leu His Arg Trp Glu Asn Asn 
    50                  55                  60                  


Ser Cys Val Glu Lys Lys Val Leu Gly Glu Lys Thr Glu Asn Pro Lys 
65                  70                  75                  80  


Lys Phe Lys Ile Asn Tyr Thr Val Ala Asn Glu Ala Thr Leu Leu Asp 
                85                  90                  95      


Thr Asp Tyr Asp Asn Phe Leu Phe Leu Cys Leu Gln Asp Thr Thr Thr 
            100                 105                 110         


Pro Ile Gln Ser Met Met Cys Gln Tyr Leu Ala Arg Val Leu Val Glu 
        115                 120                 125             


Asp Asp Glu Ile Met Gln Gly Phe Ile Arg Ala Phe Arg Pro Leu Pro 
    130                 135                 140                 


Arg His Leu Trp Tyr Leu Leu Asp Leu Lys Gln Met Glu Glu Pro Cys 
145                 150                 155                 160 


Arg Phe 
        


<210>  2044
<211>  335
<212>  PRT
<213>  Homo Sapiens

<400>  2044

Ser Trp Trp Tyr Met Arg Ala Thr Gly Gly Ser Ser Arg Val Met Cys 
1               5                   10                  15      


Asp Asn Val Pro Gly Leu Val Ser Ser Gln Arg Gln Leu Cys His Arg 
            20                  25                  30          


His Pro Asp Val Met Arg Ala Ile Ser Gln Gly Val Ala Glu Trp Thr 
        35                  40                  45              


Ala Glu Cys Gln His Gln Phe Arg Gln His Arg Trp Asn Cys Asn Thr 
    50                  55                  60                  


Leu Asp Arg Asp His Ser Leu Phe Gly Arg Val Leu Leu Arg Ser Ser 
65                  70                  75                  80  


Arg Glu Ser Ala Phe Val Tyr Ala Ile Ser Ser Ala Gly Val Val Phe 
                85                  90                  95      


Ala Ile Thr Arg Ala Cys Ser Gln Gly Glu Val Lys Ser Cys Ser Cys 
            100                 105                 110         


Asp Pro Lys Lys Met Gly Ser Ala Lys Asp Ser Lys Gly Ile Phe Asp 
        115                 120                 125             


Trp Gly Gly Cys Ser Asp Asn Ile Asp Tyr Gly Ile Lys Phe Ala Arg 
    130                 135                 140                 


Ala Phe Val Asp Ala Lys Glu Arg Lys Gly Lys Asp Ala Arg Ala Leu 
145                 150                 155                 160 


Met Asn Leu His Asn Asn Arg Ala Gly Arg Lys Ala Val Lys Arg Phe 
                165                 170                 175     


Leu Lys Gln Glu Cys Lys Cys His Gly Val Ser Gly Ser Cys Thr Leu 
            180                 185                 190         


Arg Thr Cys Trp Leu Ala Met Ala Asp Phe Arg Lys Thr Gly Asp Tyr 
        195                 200                 205             


Leu Trp Arg Lys Tyr Asn Gly Ala Ile Gln Val Val Met Asn Gln Asp 
    210                 215                 220                 


Gly Thr Gly Phe Thr Val Ala Asn Glu Arg Phe Lys Lys Pro Thr Lys 
225                 230                 235                 240 


Asn Asp Leu Val Tyr Phe Glu Asn Ser Pro Asp Tyr Cys Ile Arg Asp 
                245                 250                 255     


Arg Glu Ala Gly Ser Leu Gly Thr Ala Gly Arg Val Cys Asn Leu Thr 
            260                 265                 270         


Ser Arg Gly Met Asp Ser Cys Glu Val Met Cys Cys Gly Arg Gly Tyr 
        275                 280                 285             


Asp Thr Ser His Val Thr Arg Met Thr Lys Cys Gly Cys Lys Phe His 
    290                 295                 300                 


Trp Cys Cys Ala Val Arg Cys Gln Asp Cys Leu Glu Ala Leu Asp Val 
305                 310                 315                 320 


His Thr Cys Lys Ala Pro Lys Asn Ala Asp Trp Thr Thr Ala Thr 
                325                 330                 335 


<210>  2045
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  2045

Glu Pro Gln Asn Cys Ser Ala Thr Lys Ser Asn Tyr Leu Arg Gly Thr 
1               5                   10                  15      


Gly Pro Tyr Pro Pro Ser Val Asp Trp Arg Lys Lys Gly Asn Phe Val 
            20                  25                  30          


Ser Pro Val Lys Asn Gln Gly Ala Cys Gly Ser Cys Trp Thr Phe Ser 
        35                  40                  45              


Thr Thr Gly Ala Leu Glu Ser Ala Ile Ala Ile Ala Thr Gly Lys Met 
    50                  55                  60                  


Leu Ser Leu Ala Glu Gln Gln Leu Val Asp Cys Ala Gln Asp Phe Asn 
65                  70                  75                  80  


Asn His Gly Cys Gln Gly Gly Leu Pro Ser Gln Ala Phe Glu Tyr Ile 
                85                  90                  95      


Leu Tyr Asn Lys Gly Ile Met Gly Glu Asp Thr Tyr Pro Tyr Gln Gly 
            100                 105                 110         


Lys Asp Gly Tyr Cys Lys Phe Gln Pro Gly Lys Ala Ile Gly Phe Val 
        115                 120                 125             


Lys Asp Val Ala Asn Ile Thr Ile Tyr Asp Glu Glu Ala Met Val Glu 
    130                 135                 140                 


Ala Val Ala Leu Tyr Asn Pro Val Ser Phe Ala Phe Glu Val Thr Gln 
145                 150                 155                 160 


Asp Phe Met Met Tyr Arg Thr Gly Ile Tyr Ser Ser Thr Ser Cys His 
                165                 170                 175     


Lys Thr Pro Asp Lys Val Asn His Ala Val Leu Ala Val Gly Tyr Gly 
            180                 185                 190         


Glu Lys Asn Gly Ile Pro Tyr Trp Ile Val Lys Asn Ser Trp Gly Pro 
        195                 200                 205             


Gln Trp Gly Met Asn Gly Tyr Phe Leu Ile Glu Arg Gly Lys Asn Met 
    210                 215                 220                 


Cys Gly Leu Ala Ala Cys Ala Ser Tyr Pro Ile Pro Leu Val 
225                 230                 235             


<210>  2046
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2046

His Thr Ala Ala Gln Asp Asn Cys Thr Cys Pro Thr Asn Lys Met Thr 
1               5                   10                  15      


Val Cys Ser Pro Asp Gly Pro Gly Gly Arg Cys Gln Cys Arg Ala Leu 
            20                  25                  30          


Gly Ser Gly Met Ala Val Asp Cys Ser Thr Leu Thr Ser Lys Cys Leu 
        35                  40                  45              


Leu Leu Lys Ala Arg Met Ser Ala Pro Lys Asn Ala Arg Thr Leu Val 
    50                  55                  60                  


Arg Pro Ser Glu His Ala Leu Val Asp Asn Asp Gly Leu Tyr Asp Pro 
65                  70                  75                  80  


Asp Cys Asp Pro Glu Gly Arg Phe Lys Ala Arg Gln Cys Asn Gln Thr 
                85                  90                  95      


Ser Val Cys Trp Cys Val Asn Ser Val Gly Val Arg Arg Thr Asp Lys 
            100                 105                 110         


Gly Asp Leu Ser Leu Arg Cys Asp Glu Leu Val Arg Thr His His Ile 
        115                 120                 125             


Leu Ile Asp Leu Arg His Arg Pro Thr Ala Gly Ala Phe Asn His Ser 
    130                 135                 140                 


Asp Leu Asp Ala Glu Leu Arg Arg Leu Phe Arg Glu Arg Tyr Arg Leu 
145                 150                 155                 160 


His Pro Lys Phe Val Ala Ala Val His Tyr Glu Gln Pro Thr Ile Gln 
                165                 170                 175     


Ile Glu Leu Arg Gln Asn Thr Ser Gln Lys Ala Ala Gly Asp Val Asp 
            180                 185                 190         


Ile Gly Asp Ala Ala Tyr Tyr Phe Glu Arg Asp Ile Lys Gly Glu Ser 
        195                 200                 205             


Leu Phe Gln Gly Arg Gly Gly Leu Asp Leu Arg Val Arg Gly Glu Pro 
    210                 215                 220                 


Leu Gln Val Glu Arg Thr Leu Ile Tyr Tyr Leu Asp Glu Ile Pro Pro 
225                 230                 235                 240 


Lys Phe Ser Met Lys Arg Leu Thr 
                245             


<210>  2047
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  2047

Val Ile Pro Ala Glu Glu Glu Asn Pro Ala Phe Trp Asn Arg Gln Ala 
1               5                   10                  15      


Ala Glu Ala Leu Asp Ala Ala Lys Lys Leu Gln Pro Ile Gln Lys Val 
            20                  25                  30          


Ala Lys Asn Leu Ile Leu Phe Leu Gly Asp Gly Leu Gly Val Pro Thr 
        35                  40                  45              


Val Thr Ala Thr Arg Ile Leu Lys Gly Gln Lys Asn Gly Lys Leu Gly 
    50                  55                  60                  


Pro Glu Thr Pro Leu Ala Met Asp Arg Phe Pro Tyr Leu Ala Leu Ser 
65                  70                  75                  80  


Lys Thr Tyr Asn Val Asp Arg Gln Val Pro Asp Ser Ala Ala Thr Ala 
                85                  90                  95      


Thr Ala Tyr Leu Cys Gly Val Lys Ala Asn Phe Gln Thr Ile Gly Leu 
            100                 105                 110         


Ser Ala Ala Ala Arg Phe Asn Gln Cys Asn Thr Thr Arg Gly Asn Glu 
        115                 120                 125             


Val Ile Ser Val Met Asn Arg Ala Lys Gln Ala Gly Lys Ser Val Gly 
    130                 135                 140                 


Val Val Thr Thr Thr Arg Val Gln His Ala Ser Pro Ala Gly Thr Tyr 
145                 150                 155                 160 


Ala His Thr Val Asn Arg Asn Trp Tyr Ser Asp Ala Asp Met Pro Ala 
                165                 170                 175     


Ser Ala Arg Gln Glu Gly Cys Gln Asp Ile Ala Thr Gln Leu Ile Ser 
            180                 185                 190         


Asn Met Asp Ile Asp Val Ile Leu Gly Gly Gly Arg Lys Tyr Met Phe 
        195                 200                 205             


Pro Met Gly Thr Pro Asp Pro Glu Tyr Pro Ala Asp Ala Ser Gln Asn 
    210                 215                 220                 


Gly Ile Arg Leu Asp Gly Lys Asn Leu Val Gln Glu Trp Leu Ala Lys 
225                 230                 235                 240 


His Gln Gly Ala Trp Tyr Val Trp Asn Arg Thr Glu Leu Met Gln Ala 
                245                 250                 255     


Ser Leu Asp Gln Ser Val Thr His Leu Met Gly Leu Phe Glu Pro Gly 
            260                 265                 270         


Asp Thr Lys Tyr Glu Ile His Arg Asp Pro Thr Leu Asp Pro Ser Leu 
        275                 280                 285             


Met Glu Met Thr Glu Ala Ala Leu Arg Leu Leu Ser Arg Asn Pro Arg 
    290                 295                 300                 


Gly Phe Tyr Leu Phe Val Glu Gly Gly Arg Ile Asp His Gly His His 
305                 310                 315                 320 


Glu Gly Val Ala Tyr Gln Ala Leu Thr Glu Ala Val Met Phe Asp Asp 
                325                 330                 335     


Ala Ile Glu Arg Ala Gly Gln Leu Thr Ser Glu Glu Asp Thr Leu Thr 
            340                 345                 350         


Leu Val Thr Ala Asp His Ser His Val Phe Ser Phe Gly Gly Tyr Thr 
        355                 360                 365             


Leu Arg Gly Ser Ser Ile Phe Gly Leu Ala Pro Ser Lys Ala Gln Asp 
    370                 375                 380                 


Ser Lys Ala Tyr Thr Ser Ile Leu Tyr Gly Asn Gly Pro Gly Tyr Val 
385                 390                 395                 400 


Phe Asn Ser Gly Val Arg Pro Asp Val Asn Glu Ser Glu Ser Gly Ser 
                405                 410                 415     


Pro Asp Tyr Gln Gln Gln Ala Ala Val Pro Leu Ser Ser Glu Thr His 
            420                 425                 430         


Gly Gly Glu Asp Val Ala Val Phe Ala Arg Gly Pro Gln Ala His Leu 
        435                 440                 445             


Val His Gly Val Gln Glu Gln Ser Phe Val Ala His Val Met Ala Phe 
    450                 455                 460                 


Ala Ala Cys Leu Glu Pro Tyr Thr Ala Cys Asp Leu Ala Pro Pro Ala 
465                 470                 475                 480 


Cys Thr Thr Asp 
                


<210>  2048
<211>  608
<212>  PRT
<213>  Homo Sapiens

<400>  2048

Asp Val Tyr Gln Glu Pro Thr Asp Pro Lys Phe Pro Gln Gln Trp Tyr 
1               5                   10                  15      


Leu Ser Gly Val Thr Gln Arg Asp Leu Asn Val Lys Ala Ala Trp Ala 
            20                  25                  30          


Gln Gly Tyr Thr Gly His Gly Ile Val Val Ser Ile Leu Asp Asp Gly 
        35                  40                  45              


Ile Glu Lys Asn His Pro Asp Leu Ala Gly Asn Tyr Asp Pro Gly Ala 
    50                  55                  60                  


Ser Phe Asp Val Asn Asp Gln Asp Pro Asp Pro Gln Pro Arg Tyr Thr 
65                  70                  75                  80  


Gln Met Asn Asp Asn Arg His Gly Thr Arg Cys Ala Gly Glu Val Ala 
                85                  90                  95      


Ala Val Ala Asn Asn Gly Val Cys Gly Val Gly Val Ala Tyr Asn Ala 
            100                 105                 110         


Arg Ile Gly Gly Val Arg Met Leu Asp Gly Glu Val Thr Asp Ala Val 
        115                 120                 125             


Glu Ala Arg Ser Leu Gly Leu Asn Pro Asn His Ile His Ile Tyr Ser 
    130                 135                 140                 


Ala Ser Trp Gly Pro Glu Asp Asp Gly Lys Thr Val Asp Gly Pro Ala 
145                 150                 155                 160 


Arg Leu Ala Glu Glu Ala Phe Phe Arg Gly Val Ser Gln Gly Arg Gly 
                165                 170                 175     


Gly Leu Gly Ser Ile Phe Val Trp Ala Ser Gly Asn Gly Gly Arg Glu 
            180                 185                 190         


His Asp Ser Cys Asn Cys Asp Gly Tyr Thr Asn Ser Ile Tyr Thr Leu 
        195                 200                 205             


Ser Ile Ser Ser Ala Thr Gln Phe Gly Asn Val Pro Trp Tyr Ser Glu 
    210                 215                 220                 


Ala Cys Ser Ser Thr Leu Ala Thr Thr Tyr Ser Ser Gly Asn Gln Asn 
225                 230                 235                 240 


Glu Lys Gln Ile Val Thr Thr Asp Leu Arg Gln Lys Cys Thr Glu Ser 
                245                 250                 255     


His Thr Gly Thr Ser Ala Ser Ala Pro Leu Ala Ala Gly Ile Ile Ala 
            260                 265                 270         


Leu Thr Leu Glu Ala Asn Lys Asn Leu Thr Trp Arg Asp Met Gln His 
        275                 280                 285             


Leu Val Val Gln Thr Ser Lys Pro Ala His Leu Asn Ala Asn Asp Trp 
    290                 295                 300                 


Ala Thr Asn Gly Val Gly Arg Lys Val Ser His Ser Tyr Gly Tyr Gly 
305                 310                 315                 320 


Leu Leu Asp Ala Gly Ala Met Val Ala Leu Ala Gln Asn Trp Thr Thr 
                325                 330                 335     


Val Ala Pro Gln Arg Lys Cys Ile Ile Asp Ile Leu Thr Glu Pro Lys 
            340                 345                 350         


Asp Ile Gly Lys Arg Leu Glu Val Arg Lys Thr Val Thr Ala Cys Leu 
        355                 360                 365             


Gly Glu Pro Asn His Ile Thr Arg Leu Glu His Ala Gln Ala Arg Leu 
    370                 375                 380                 


Thr Leu Ser Tyr Asn Arg Arg Gly Asp Leu Ala Ile His Leu Val Ser 
385                 390                 395                 400 


Pro Met Gly Thr Arg Ser Thr Leu Leu Ala Ala Arg Pro His Asp Tyr 
                405                 410                 415     


Ser Ala Asp Gly Phe Asn Asp Trp Ala Phe Met Thr Thr His Ser Trp 
            420                 425                 430         


Asp Glu Asp Pro Ser Gly Glu Trp Val Leu Glu Ile Glu Asn Thr Ser 
        435                 440                 445             


Glu Ala Asn Asn Tyr Gly Thr Leu Thr Lys Phe Thr Leu Val Leu Tyr 
    450                 455                 460                 


Gly Thr Ala Pro Glu Gly Leu Pro Val Pro Pro Glu Ser Ser Gly Cys 
465                 470                 475                 480 


Lys Thr Leu Thr Ser Ser Gln Ala Cys Val Val Cys Glu Glu Gly Phe 
                485                 490                 495     


Ser Leu His Gln Lys Ser Cys Val Gln His Cys Pro Pro Gly Phe Ala 
            500                 505                 510         


Pro Gln Val Leu Asp Thr His Tyr Ser Thr Glu Asn Asp Val Glu Thr 
        515                 520                 525             


Ile Arg Ala Ser Val Cys Ala Pro Cys His Ala Ser Cys Ala Thr Cys 
    530                 535                 540                 


Gln Gly Pro Ala Leu Thr Asp Cys Leu Ser Cys Pro Ser His Ala Ser 
545                 550                 555                 560 


Leu Asp Pro Val Glu Gln Thr Cys Ser Arg Gln Ser Gln Ser Ser Arg 
                565                 570                 575     


Glu Ser Pro Pro Gln Gln Gln Pro Pro Arg Leu Pro Pro Glu Val Glu 
            580                 585                 590         


Ala Gly Gln Arg Leu Arg Ala Gly Leu Leu Pro Ser His Leu Pro Glu 
        595                 600                 605             


<210>  2049
<211>  314
<212>  PRT
<213>  Homo Sapiens

<400>  2049

Gln Asp Thr Cys Arg Gln Gly His Pro Gly Ile Pro Gly Asn Pro Gly 
1               5                   10                  15      


His Asn Gly Leu Pro Gly Arg Asp Gly Arg Asp Gly Ala Lys Gly Asp 
            20                  25                  30          


Lys Gly Asp Ala Gly Glu Pro Gly Arg Pro Gly Ser Pro Gly Lys Asp 
        35                  40                  45              


Gly Thr Ser Gly Glu Lys Gly Glu Arg Gly Ala Asp Gly Lys Val Glu 
    50                  55                  60                  


Ala Lys Gly Ile Lys Gly Asp Gln Gly Ser Arg Gly Ser Pro Gly Lys 
65                  70                  75                  80  


His Gly Pro Lys Gly Leu Ala Gly Pro Met Gly Glu Lys Gly Leu Arg 
                85                  90                  95      


Gly Glu Thr Gly Pro Gln Gly Gln Lys Gly Asn Lys Gly Asp Val Gly 
            100                 105                 110         


Pro Thr Gly Pro Glu Gly Pro Arg Gly Asn Ile Gly Pro Leu Gly Pro 
        115                 120                 125             


Thr Gly Leu Pro Gly Pro Met Gly Pro Ile Gly Lys Pro Gly Pro Lys 
    130                 135                 140                 


Gly Glu Ala Gly Pro Thr Gly Pro Gln Gly Glu Pro Gly Val Arg Gly 
145                 150                 155                 160 


Ile Arg Gly Trp Lys Gly Asp Arg Gly Glu Lys Gly Lys Ile Gly Glu 
                165                 170                 175     


Thr Leu Val Leu Pro Lys Ser Ala Phe Thr Val Gly Leu Thr Val Leu 
            180                 185                 190         


Ser Lys Phe Pro Ser Ser Asp Val Pro Ile Lys Phe Asp Lys Ile Leu 
        195                 200                 205             


Tyr Asn Glu Phe Asn His Tyr Asp Thr Ala Ala Gly Lys Phe Thr Cys 
    210                 215                 220                 


His Ile Ala Gly Val Tyr Tyr Phe Thr Tyr His Ile Thr Val Phe Ser 
225                 230                 235                 240 


Arg Asn Val Gln Val Ser Leu Val Lys Asn Gly Val Lys Ile Leu His 
                245                 250                 255     


Thr Lys Asp Ala Tyr Met Ser Ser Glu Asp Gln Ala Ser Gly Gly Ile 
            260                 265                 270         


Val Leu Gln Leu Lys Leu Gly Asp Glu Val Trp Leu Gln Val Thr Gly 
        275                 280                 285             


Gly Glu Arg Phe Asn Gly Leu Phe Ala Asp Glu Asp Asp Asp Thr Thr 
    290                 295                 300                 


Phe Thr Gly Phe Leu Leu Phe Ser Ser Pro 
305                 310                 


<210>  2050
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  2050

Val Asp Glu Gln Pro Leu Glu Asn Tyr Leu Asp Met Glu Tyr Phe Gly 
1               5                   10                  15      


Thr Ile Gly Ile Gly Thr Pro Ala Gln Asp Phe Thr Val Val Phe Asp 
            20                  25                  30          


Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Val Tyr Cys Ser Ser Leu 
        35                  40                  45              


Ala Cys Thr Asn His Asn Arg Phe Asn Pro Glu Asp Ser Ser Thr Tyr 
    50                  55                  60                  


Gln Ser Thr Ser Glu Thr Val Ser Ile Thr Tyr Gly Thr Gly Ser Met 
65                  70                  75                  80  


Thr Gly Ile Leu Gly Tyr Asp Thr Val Gln Val Gly Gly Ile Ser Asp 
                85                  90                  95      


Thr Asn Gln Ile Phe Gly Leu Ser Glu Thr Glu Pro Gly Ser Phe Leu 
            100                 105                 110         


Tyr Tyr Ala Pro Phe Asp Gly Ile Leu Gly Leu Ala Tyr Pro Ser Ile 
        115                 120                 125             


Ser Ser Ser Gly Ala Thr Pro Val Phe Asp Asn Ile Trp Asn Gln Gly 
    130                 135                 140                 


Leu Val Ser Gln Asp Leu Phe Ser Val Tyr Leu Ser Ala Asp Asp Gln 
145                 150                 155                 160 


Ser Gly Ser Val Val Ile Phe Gly Gly Ile Asp Ser Ser Tyr Tyr Thr 
                165                 170                 175     


Gly Ser Leu Asn Trp Val Pro Val Thr Val Glu Gly Tyr Trp Gln Ile 
            180                 185                 190         


Thr Val Asp Ser Ile Thr Met Asn Gly Glu Ala Ile Ala Cys Ala Glu 
        195                 200                 205             


Gly Cys Gln Ala Ile Val Asp Thr Gly Thr Ser Leu Leu Thr Gly Pro 
    210                 215                 220                 


Thr Ser Pro Ile Ala Asn Ile Gln Ser Asp Ile Gly Ala Ser Glu Asn 
225                 230                 235                 240 


Ser Asp Gly Asp Met Val Val Ser Cys Ser Ala Ile Ser Ser Leu Pro 
                245                 250                 255     


Asp Ile Val Phe Thr Ile Asn Gly Val Gln Tyr Pro Val Pro Pro Ser 
            260                 265                 270         


Ala Tyr Ile Leu Gln Ser Glu Gly Ser Cys Ile Ser Gly Phe Gln Gly 
        275                 280                 285             


Met Asn Leu Pro Thr Glu Ser Gly Glu Leu Trp Ile Leu Gly Asp Val 
    290                 295                 300                 


Phe Ile Arg Gln Tyr Phe Thr Val Phe Asp Arg Ala Asn Asn Gln Val 
305                 310                 315                 320 


Gly Leu Ala Pro Val Ala 
                325     


<210>  2051
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  2051

Val Asp Glu Gln Pro Leu Glu Asn Tyr Leu Asp Met Glu Tyr Phe Gly 
1               5                   10                  15      


Thr Ile Gly Ile Gly Thr Pro Ala Gln Asp Phe Thr Val Leu Phe Asp 
            20                  25                  30          


Thr Gly Ser Ser Asn Leu Trp Val Pro Ser Val Tyr Cys Ser Ser Leu 
        35                  40                  45              


Ala Cys Thr Asn His Asn Arg Phe Asn Pro Glu Asp Ser Ser Thr Tyr 
    50                  55                  60                  


Gln Ser Thr Ser Glu Thr Val Ser Ile Thr Tyr Gly Thr Gly Ser Met 
65                  70                  75                  80  


Thr Gly Ile Leu Gly Tyr Asp Thr Val Gln Val Gly Gly Ile Ser Asp 
                85                  90                  95      


Thr Asn Gln Ile Phe Gly Leu Ser Glu Thr Glu Pro Gly Ser Phe Leu 
            100                 105                 110         


Tyr Tyr Ala Pro Phe Asp Gly Ile Leu Gly Leu Ala Tyr Pro Ser Ile 
        115                 120                 125             


Ser Ser Ser Gly Ala Thr Pro Val Phe Asp Asn Ile Trp Asn Gln Gly 
    130                 135                 140                 


Leu Val Ser Gln Asp Leu Phe Ser Val Tyr Leu Ser Ala Asp Asp Gln 
145                 150                 155                 160 


Ser Gly Ser Val Val Ile Phe Gly Gly Ile Asp Ser Ser Tyr Tyr Thr 
                165                 170                 175     


Gly Ser Leu Asn Trp Val Pro Val Thr Val Glu Gly Tyr Trp Gln Ile 
            180                 185                 190         


Thr Val Asp Ser Ile Thr Met Asn Gly Glu Ala Ile Ala Cys Ala Glu 
        195                 200                 205             


Gly Cys Gln Ala Ile Val Asp Thr Gly Thr Ser Leu Leu Thr Gly Pro 
    210                 215                 220                 


Thr Ser Pro Ile Ala Asn Ile Gln Ser Asp Ile Gly Ala Ser Glu Asn 
225                 230                 235                 240 


Ser Asp Gly Asp Met Val Val Ser Cys Ser Ala Ile Ser Ser Leu Pro 
                245                 250                 255     


Asp Ile Val Phe Thr Ile Asn Gly Val Gln Tyr Pro Val Pro Pro Ser 
            260                 265                 270         


Ala Tyr Ile Leu Gln Ser Glu Gly Ser Cys Ile Ser Gly Phe Gln Gly 
        275                 280                 285             


Met Asn Leu Pro Thr Glu Ser Gly Glu Leu Trp Ile Leu Gly Asp Val 
    290                 295                 300                 


Phe Ile Arg Gln Tyr Phe Thr Val Phe Asp Arg Thr Asn Asn Gln Val 
305                 310                 315                 320 


Gly Leu Ala Pro Val Ala 
                325     


<210>  2052
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  2052

Arg Ser Phe Phe Ser Phe Leu Gly Glu Ala Phe Asp Gly Ala Arg Asp 
1               5                   10                  15      


Met Trp Arg Ala Tyr Ser Asp Met Arg Glu Ala Asn Tyr Ile Gly Ser 
            20                  25                  30          


Asp Lys Tyr Phe His Ala Arg Gly Asn Tyr Asp Ala Ala Lys Arg Gly 
        35                  40                  45              


Pro Gly Gly Ala Trp Ala Ala Glu Val Ile Ser Asp Ala Arg Glu Asn 
    50                  55                  60                  


Ile Gln Arg Phe Phe Gly His Gly Ala Glu Asp Ser Leu Ala Asp Gln 
65                  70                  75                  80  


Ala Ala Asn Glu Trp Gly Arg Ser Gly Lys Asp Pro Asn His Phe Arg 
                85                  90                  95      


Pro Ala Gly Leu Pro Glu Lys Tyr 
            100                 


<210>  2053
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  2053

Arg Ser Phe Phe Ser Phe Leu Gly Glu Ala Phe Asp Gly Ala Arg Asp 
1               5                   10                  15      


Met Trp Arg Ala Tyr Ser Asp Met Arg Glu Ala Asn Tyr Ile Gly Ser 
            20                  25                  30          


Asp Lys Tyr Phe His Ala Arg Gly Asn Tyr Asp Ala Ala Lys Arg Gly 
        35                  40                  45              


Pro Gly Gly Ala Trp Ala Ala Glu Val Ile Ser Asn Ala Arg Glu Asn 
    50                  55                  60                  


Ile Gln Arg Leu Thr Gly His Gly Ala Glu Asp Ser Leu Ala Asp Gln 
65                  70                  75                  80  


Ala Ala Asn Lys Trp Gly Arg Ser Gly Arg Asp Pro Asn His Phe Arg 
                85                  90                  95      


Pro Ala Gly Leu Pro Glu Lys Tyr 
            100                 


<210>  2054
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  2054

Val Gln Thr Val Pro Leu Ser Arg Leu Phe Asp His Ala Met Leu Gln 
1               5                   10                  15      


Ala His Arg Ala His Gln Leu Ala Ile Asp Thr Tyr Gln Glu Phe Glu 
            20                  25                  30          


Glu Thr Tyr Ile Pro Lys Asp Gln Lys Tyr Ser Phe Leu His Asp Ser 
        35                  40                  45              


Gln Thr Ser Phe Cys Phe Ser Asp Ser Ile Pro Thr Pro Ser Asn Met 
    50                  55                  60                  


Glu Glu Thr Gln Gln Lys Ser Asn Leu Glu Leu Leu Arg Ile Ser Leu 
65                  70                  75                  80  


Leu Leu Ile Glu Ser Trp Leu Glu Pro Val Arg Phe Leu Arg Ser Met 
                85                  90                  95      


Phe Ala Asn Asn Leu Val Tyr Asp Thr Ser Asp Ser Asp Asp Tyr His 
            100                 105                 110         


Leu Leu Lys Asp Leu Glu Glu Gly Ile Gln Thr Leu Met Gly Arg Leu 
        115                 120                 125             


Glu Asp Gly Ser Arg Arg Thr Gly Gln Ile Leu Lys Gln Thr Tyr Ser 
    130                 135                 140                 


Lys Phe Asp Thr Asn Ser His Asn His Asp Ala Leu Leu Lys Asn Tyr 
145                 150                 155                 160 


Gly Leu Leu Tyr Cys Phe Arg Lys Asp Met Asp Lys Val Glu Thr Phe 
                165                 170                 175     


Leu Arg Met Val Gln Cys Arg Ser Val Glu Gly Ser Cys Gly Phe 
            180                 185                 190     


<210>  2055
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  2055

Val Gln Thr Val Pro Leu Ser Arg Leu Phe Asp His Ala Met Leu Gln 
1               5                   10                  15      


Ala His Arg Ala His Gln Leu Ala Ile Asp Thr Tyr Gln Glu Phe Glu 
            20                  25                  30          


Glu Thr Tyr Ile Pro Lys Asp Gln Lys Tyr Ser Phe Leu His Asp Ser 
        35                  40                  45              


Gln Thr Ser Phe Cys Phe Ser Asp Ser Ile Pro Thr Pro Ser Asn Met 
    50                  55                  60                  


Glu Glu Thr Gln Gln Lys Ser Asn Leu Glu Leu Leu Arg Ile Ser Leu 
65                  70                  75                  80  


Leu Leu Ile Glu Ser Trp Leu Glu Pro Val Arg Phe Leu Arg Ser Met 
                85                  90                  95      


Phe Ala Asn Asn Leu Val Tyr Asp Thr Ser Asp Ser Asp Asp Tyr His 
            100                 105                 110         


Leu Leu Lys Asp Leu Glu Glu Gly Ile Gln Thr Leu Met Gly Arg Leu 
        115                 120                 125             


Glu Asp Gly Ser Arg Arg Thr Gly Gln Ile Leu Lys Gln Thr Tyr Ser 
    130                 135                 140                 


Lys Phe Asp Thr Asn Ser His Asn His Asp Ala Leu Leu Lys Asn Tyr 
145                 150                 155                 160 


Gly Leu Leu Tyr Cys Phe Arg Lys Asp Met Asp Lys Val Glu Thr Phe 
                165                 170                 175     


Leu Arg Met Val Gln Cys Arg Ser Val Glu Gly Ser Cys Gly Phe 
            180                 185                 190     


<210>  2056
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  2056

Glu Asp Asn Asp Glu Phe Phe Met Asp Phe Leu Gln Thr Leu Leu Val 
1               5                   10                  15      


Gly Thr Pro Glu Glu Leu Tyr Glu Gly Thr Leu Gly Lys Tyr Asn Val 
            20                  25                  30          


Asn Glu Asp Ala Lys Ala Ala Met Thr Glu Leu Lys Ser Cys Arg Asp 
        35                  40                  45              


Gly Leu Gln Pro Met His Lys Ala Glu Leu Val Lys Leu Leu Val Gln 
    50                  55                  60                  


Val Leu Gly Ser Gln Asp Gly Ala 
65                  70          


<210>  2057
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  2057

Tyr Pro Thr Gln Arg Ala Arg Tyr Gln Trp Val Arg Cys Asn Pro Asp 
1               5                   10                  15      


Ser Asn Ser Ala Asn Cys Leu Glu Glu Lys Gly Pro Met Phe Glu Leu 
            20                  25                  30          


Leu Pro Gly Glu Ser Asn Lys Ile Pro Arg Leu Arg Thr Asp Leu Phe 
        35                  40                  45              


Pro Lys Thr Arg Ile Gln Asp Leu Asn Arg Ile Phe Pro Leu Ser Glu 
    50                  55                  60                  


Asp Tyr Ser Gly Ser Gly Phe Gly Ser Gly Ser Gly Ser Gly Ser Gly 
65                  70                  75                  80  


Ser Gly Ser Gly Phe Leu Thr Glu Met Glu Gln Asp Tyr Gln Leu Val 
                85                  90                  95      


Asp Glu Ser Asp Ala Phe His Asp Asn Leu Arg Ser Leu Asp Arg Asn 
            100                 105                 110         


Leu Pro Ser Asp Ser Gln Asp Leu Gly Gln His Gly Leu Glu Glu Asp 
        115                 120                 125             


Phe Met Leu 
    130     


<210>  2058
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  2058

Ile Ile Gly Gly His Glu Ala Lys Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Tyr Leu Met Ile Trp Asp Gln Lys Ser Leu Lys Arg Cys Gly Gly Phe 
            20                  25                  30          


Leu Ile Gln Asp Asp Phe Val Leu Thr Ala Ala His Cys Trp Gly Ser 
        35                  40                  45              


Ser Ile Asn Val Thr Leu Gly Ala His Asn Ile Lys Glu Gln Glu Pro 
    50                  55                  60                  


Thr Gln Gln Phe Ile Pro Val Lys Arg Pro Ile Pro His Pro Ala Tyr 
65                  70                  75                  80  


Asn Pro Lys Asn Phe Ser Asn Asp Ile Met Leu Leu Gln Leu Glu Arg 
                85                  90                  95      


Lys Ala Lys Arg Thr Arg Ala Val Gln Pro Leu Arg Leu Pro Ser Asn 
            100                 105                 110         


Lys Ala Gln Val Lys Pro Gly Gln Thr Cys Ser Val Ala Gly Trp Gly 
        115                 120                 125             


Gln Thr Ala Pro Leu Gly Lys His Ser His Thr Leu Gln Glu Val Lys 
    130                 135                 140                 


Met Thr Val Gln Glu Asp Arg Lys Cys Glu Ser Asp Leu Arg His Tyr 
145                 150                 155                 160 


Tyr Asp Ser Thr Ile Glu Leu Cys Val Gly Asp Pro Glu Ile Lys Lys 
                165                 170                 175     


Thr Ser Phe Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Asn Lys Val 
            180                 185                 190         


Ala Gln Gly Ile Val Ser Tyr Gly Arg Asn Asn Gly Met Pro Pro Arg 
        195                 200                 205             


Ala Cys Thr Lys Val Ser Ser Phe Val His Trp Ile Lys Lys Thr Met 
    210                 215                 220                 


Lys Arg His 
225         


<210>  2059
<211>  134
<212>  PRT
<213>  Homo Sapiens

<400>  2059

Lys Pro Pro Gln Phe Thr Trp Ala Gln Trp Phe Glu Thr Gln His Ile 
1               5                   10                  15      


Asn Met Thr Ser Gln Gln Cys Thr Asn Ala Met Gln Val Ile Asn Asn 
            20                  25                  30          


Tyr Gln Arg Arg Cys Lys Asn Gln Asn Thr Phe Leu Leu Thr Thr Phe 
        35                  40                  45              


Ala Asn Val Val Asn Val Cys Gly Asn Pro Asn Met Thr Cys Pro Ser 
    50                  55                  60                  


Asn Lys Thr Arg Lys Asn Cys His His Ser Gly Ser Gln Val Pro Leu 
65                  70                  75                  80  


Ile His Cys Asn Leu Thr Thr Pro Ser Pro Gln Asn Ile Ser Asn Cys 
                85                  90                  95      


Arg Tyr Ala Gln Thr Pro Ala Asn Met Phe Tyr Ile Val Ala Cys Asp 
            100                 105                 110         


Asn Arg Asp Gln Arg Arg Asp Pro Pro Gln Tyr Pro Val Val Pro Val 
        115                 120                 125             


His Leu Asp Arg Ile Ile 
    130                 


<210>  2060
<211>  883
<212>  PRT
<213>  Homo Sapiens

<400>  2060

Ala His Pro Gly Arg Pro Arg Ala Val Pro Thr Gln Cys Asp Val Pro 
1               5                   10                  15      


Pro Asn Ser Arg Phe Asp Cys Ala Pro Asp Lys Ala Ile Thr Gln Glu 
            20                  25                  30          


Gln Cys Glu Ala Arg Gly Cys Cys Tyr Ile Pro Ala Lys Gln Gly Leu 
        35                  40                  45              


Gln Gly Ala Gln Met Gly Gln Pro Trp Cys Phe Phe Pro Pro Ser Tyr 
    50                  55                  60                  


Pro Ser Tyr Lys Leu Glu Asn Leu Ser Ser Ser Glu Met Gly Tyr Thr 
65                  70                  75                  80  


Ala Thr Leu Thr Arg Thr Thr Pro Thr Phe Phe Pro Lys Asp Ile Leu 
                85                  90                  95      


Thr Leu Arg Leu Asp Val Met Met Glu Thr Glu Asn Arg Leu His Phe 
            100                 105                 110         


Thr Ile Lys Asp Pro Ala Asn Arg Arg Tyr Glu Val Pro Leu Glu Thr 
        115                 120                 125             


Pro His Val His Ser Arg Ala Pro Ser Pro Leu Tyr Ser Val Glu Phe 
    130                 135                 140                 


Ser Glu Glu Pro Phe Gly Val Ile Val Arg Arg Gln Leu Asp Gly Arg 
145                 150                 155                 160 


Val Leu Leu Asn Thr Thr Val Ala Pro Leu Phe Phe Ala Asp Gln Phe 
                165                 170                 175     


Leu Gln Leu Ser Thr Ser Leu Pro Ser Gln Tyr Ile Thr Gly Leu Ala 
            180                 185                 190         


Glu His Leu Ser Pro Leu Met Leu Ser Thr Ser Trp Thr Arg Ile Thr 
        195                 200                 205             


Leu Trp Asn Arg Asp Leu Ala Pro Thr Pro Gly Ala Asn Leu Tyr Gly 
    210                 215                 220                 


Ser His Pro Phe Tyr Leu Ala Leu Glu Asp Gly Gly Ser Ala His Gly 
225                 230                 235                 240 


Val Phe Leu Leu Asn Ser Asn Ala Met Asp Val Val Leu Gln Pro Ser 
                245                 250                 255     


Pro Ala Leu Ser Trp Arg Ser Thr Gly Gly Ile Leu Asp Val Tyr Ile 
            260                 265                 270         


Phe Leu Gly Pro Glu Pro Lys Ser Val Val Gln Gln Tyr Leu Asp Val 
        275                 280                 285             


Val Gly Tyr Pro Phe Met Pro Pro Tyr Trp Gly Leu Gly Phe His Leu 
    290                 295                 300                 


Cys Arg Trp Gly Tyr Ser Ser Thr Ala Ile Thr Arg Gln Val Val Glu 
305                 310                 315                 320 


Asn Met Thr Arg Ala His Phe Pro Leu Asp Val Gln Trp Asn Asp Leu 
                325                 330                 335     


Asp Tyr Met Asp Ser Arg Arg Asp Phe Thr Phe Asn Lys Asp Gly Phe 
            340                 345                 350         


Arg Asp Phe Pro Ala Met Val Gln Glu Leu His Gln Gly Gly Arg Arg 
        355                 360                 365             


Tyr Met Met Ile Val Asp Pro Ala Ile Ser Ser Ser Gly Pro Ala Gly 
    370                 375                 380                 


Ser Tyr Arg Pro Tyr Asp Glu Gly Leu Arg Arg Gly Val Phe Ile Thr 
385                 390                 395                 400 


Asn Glu Thr Gly Gln Pro Leu Ile Gly Lys Val Trp Pro Gly Ser Thr 
                405                 410                 415     


Ala Phe Pro Asp Phe Thr Asn Pro Thr Ala Leu Ala Trp Trp Glu Asp 
            420                 425                 430         


Met Val Ala Glu Phe His Asp Gln Val Pro Phe Asp Gly Met Trp Ile 
        435                 440                 445             


Asp Met Asn Glu Pro Ser Asn Phe Ile Arg Gly Ser Glu Asp Gly Cys 
    450                 455                 460                 


Pro Asn Asn Glu Leu Glu Asn Pro Pro Tyr Val Pro Gly Val Val Gly 
465                 470                 475                 480 


Gly Thr Leu Gln Ala Ala Thr Ile Cys Ala Ser Ser His Gln Phe Leu 
                485                 490                 495     


Ser Thr His Tyr Asn Leu His Asn Leu Tyr Gly Leu Thr Glu Ala Ile 
            500                 505                 510         


Ala Ser His Arg Ala Leu Val Lys Ala Arg Gly Thr Arg Pro Phe Val 
        515                 520                 525             


Ile Ser Arg Ser Thr Phe Ala Gly His Gly Arg Tyr Ala Gly His Trp 
    530                 535                 540                 


Thr Gly Asp Val Trp Ser Ser Trp Glu Gln Leu Ala Ser Ser Val Pro 
545                 550                 555                 560 


Glu Ile Leu Gln Phe Asn Leu Leu Gly Val Pro Leu Val Gly Ala Asp 
                565                 570                 575     


Val Cys Gly Phe Leu Gly Asn Thr Ser Glu Glu Leu Cys Val Arg Trp 
            580                 585                 590         


Thr Gln Leu Gly Ala Phe Tyr Pro Phe Met Arg Asn His Asn Ser Leu 
        595                 600                 605             


Leu Ser Leu Pro Gln Glu Pro Tyr Ser Phe Ser Glu Pro Ala Gln Gln 
    610                 615                 620                 


Ala Met Arg Lys Ala Leu Thr Leu Arg Tyr Ala Leu Leu Pro His Leu 
625                 630                 635                 640 


Tyr Thr Leu Phe His Gln Ala His Val Ala Gly Glu Thr Val Ala Arg 
                645                 650                 655     


Pro Leu Phe Leu Glu Phe Pro Lys Asp Ser Ser Thr Trp Thr Val Asp 
            660                 665                 670         


His Gln Leu Leu Trp Gly Glu Ala Leu Leu Ile Thr Pro Val Leu Gln 
        675                 680                 685             


Ala Gly Lys Ala Glu Val Thr Gly Tyr Phe Pro Leu Gly Thr Trp Tyr 
    690                 695                 700                 


Asp Leu Gln Thr Val Pro Val Glu Ala Leu Gly Ser Leu Pro Pro Pro 
705                 710                 715                 720 


Pro Ala Ala Pro Arg Glu Pro Ala Ile His Ser Glu Gly Gln Trp Val 
                725                 730                 735     


Thr Leu Pro Ala Pro Leu Asp Thr Ile Asn Val His Leu Arg Ala Gly 
            740                 745                 750         


Tyr Ile Ile Pro Leu Gln Gly Pro Gly Leu Thr Thr Thr Glu Ser Arg 
        755                 760                 765             


Gln Gln Pro Met Ala Leu Ala Val Ala Leu Thr Lys Gly Gly Glu Ala 
    770                 775                 780                 


Arg Gly Glu Leu Phe Trp Asp Asp Gly Glu Ser Leu Glu Val Leu Glu 
785                 790                 795                 800 


Arg Gly Ala Tyr Thr Gln Val Ile Phe Leu Ala Arg Asn Asn Thr Ile 
                805                 810                 815     


Val Asn Glu Leu Val Arg Val Thr Ser Glu Gly Ala Gly Leu Gln Leu 
            820                 825                 830         


Gln Lys Val Thr Val Leu Gly Val Ala Thr Ala Pro Gln Gln Val Leu 
        835                 840                 845             


Ser Asn Gly Val Pro Val Ser Asn Phe Thr Tyr Ser Pro Asp Thr Lys 
    850                 855                 860                 


Val Leu Asp Ile Cys Val Ser Leu Leu Met Gly Glu Gln Phe Leu Val 
865                 870                 875                 880 


Ser Trp Cys 
            


<210>  2061
<211>  402
<212>  PRT
<213>  Homo Sapiens

<400>  2061

Lys Asp Asn Ala Thr Cys Asp Gly Pro Cys Gly Leu Arg Phe Arg Gln 
1               5                   10                  15      


Asn Pro Gln Gly Gly Val Arg Ile Val Gly Gly Lys Ala Ala Gln His 
            20                  25                  30          


Gly Ala Trp Pro Trp Met Val Ser Leu Gln Ile Phe Thr Tyr Asn Ser 
        35                  40                  45              


His Arg Tyr His Thr Cys Gly Gly Ser Leu Leu Asn Ser Arg Trp Val 
    50                  55                  60                  


Leu Thr Ala Ala His Cys Phe Val Gly Lys Asn Asn Val His Asp Trp 
65                  70                  75                  80  


Arg Leu Val Phe Gly Ala Lys Glu Ile Thr Tyr Gly Asn Asn Lys Pro 
                85                  90                  95      


Val Lys Ala Pro Leu Gln Glu Arg Tyr Val Glu Lys Ile Ile Ile His 
            100                 105                 110         


Glu Lys Tyr Asn Ser Ala Thr Glu Gly Asn Asp Ile Ala Leu Val Glu 
        115                 120                 125             


Ile Thr Pro Pro Ile Ser Cys Gly Arg Phe Ile Gly Pro Gly Cys Leu 
    130                 135                 140                 


Pro His Phe Lys Ala Gly Leu Pro Arg Gly Ser Gln Ser Cys Trp Val 
145                 150                 155                 160 


Ala Gly Trp Gly Tyr Ile Glu Glu Lys Ala Pro Arg Pro Ser Ser Ile 
                165                 170                 175     


Leu Met Glu Ala Arg Val Asp Leu Ile Asp Leu Asp Leu Cys Asn Ser 
            180                 185                 190         


Thr Gln Trp Tyr Asn Gly Arg Val Gln Pro Thr Asn Val Cys Ala Gly 
        195                 200                 205             


Tyr Pro Val Gly Lys Ile Asp Thr Cys Gln Gly Asp Ser Gly Gly Pro 
    210                 215                 220                 


Leu Met Cys Lys Asp Ser Lys Glu Ser Ala Tyr Val Val Val Gly Ile 
225                 230                 235                 240 


Thr Ser Trp Gly Val Gly Cys Ala Arg Ala Lys Arg Pro Gly Ile Tyr 
                245                 250                 255     


Thr Ala Thr Trp Pro Tyr Leu Asn Trp Ile Ala Ser Lys Ile Gly Ser 
            260                 265                 270         


Asn Ala Leu Arg Val Ile Gln Ser Ala Thr Pro Pro Pro Pro Thr Thr 
        275                 280                 285             


Arg Pro Pro Pro Ile Arg Pro Pro Phe Ser His Pro Ile Ser Ala His 
    290                 295                 300                 


Leu Pro Trp Tyr Phe Gln Pro Pro Pro Arg Pro Leu Pro Pro Arg Pro 
305                 310                 315                 320 


Pro Ala Ala Gln Pro Arg Pro Pro Pro Ser Pro Pro Pro Pro Pro Pro 
                325                 330                 335     


Pro Pro Ala Ser Pro Leu Pro Pro Pro Pro Pro Pro Pro Pro Pro Thr 
            340                 345                 350         


Pro Ser Ser Thr Thr Lys Leu Pro Gln Gly Leu Ser Phe Ala Lys Arg 
        355                 360                 365             


Leu Gln Gln Leu Ile Glu Val Leu Lys Gly Lys Thr Tyr Ser Asp Gly 
    370                 375                 380                 


Lys Asn His Tyr Asp Met Glu Thr Thr Glu Leu Pro Glu Leu Thr Ser 
385                 390                 395                 400 


Thr Ser 
        


<210>  2062
<211>  298
<212>  PRT
<213>  Homo Sapiens

<400>  2062

Ile Pro Val Lys Gln Ala Asp Ser Gly Ser Ser Glu Glu Lys Gln Leu 
1               5                   10                  15      


Tyr Asn Lys Tyr Pro Asp Ala Val Ala Thr Trp Leu Asn Pro Asp Pro 
            20                  25                  30          


Ser Gln Lys Gln Asn Leu Leu Ala Pro Gln Asn Ala Val Ser Ser Glu 
        35                  40                  45              


Glu Thr Asn Asp Phe Lys Gln Glu Thr Leu Pro Ser Lys Ser Asn Glu 
    50                  55                  60                  


Ser His Asp His Met Asp Asp Met Asp Asp Glu Asp Asp Asp Asp His 
65                  70                  75                  80  


Val Asp Ser Gln Asp Ser Ile Asp Ser Asn Asp Ser Asp Asp Val Asp 
                85                  90                  95      


Asp Thr Asp Asp Ser His Gln Ser Asp Glu Ser His His Ser Asp Glu 
            100                 105                 110         


Ser Asp Glu Leu Val Thr Asp Phe Pro Thr Asp Leu Pro Ala Thr Glu 
        115                 120                 125             


Val Phe Thr Pro Val Val Pro Thr Val Asp Thr Tyr Asp Gly Arg Gly 
    130                 135                 140                 


Asp Ser Val Val Tyr Gly Leu Arg Ser Lys Ser Lys Lys Phe Arg Arg 
145                 150                 155                 160 


Pro Asp Ile Gln Tyr Pro Asp Ala Thr Asp Glu Asp Ile Thr Ser His 
                165                 170                 175     


Met Glu Ser Glu Glu Leu Asn Gly Ala Tyr Lys Ala Ile Pro Val Ala 
            180                 185                 190         


Gln Asp Leu Asn Ala Pro Ser Asp Trp Asp Ser Arg Gly Lys Asp Ser 
        195                 200                 205             


Tyr Glu Thr Ser Gln Leu Asp Asp Gln Ser Ala Glu Thr His Ser His 
    210                 215                 220                 


Lys Gln Ser Arg Leu Tyr Lys Arg Lys Ala Asn Asp Glu Ser Asn Glu 
225                 230                 235                 240 


His Ser Asp Val Ile Asp Ser Gln Glu Leu Ser Lys Val Ser Arg Glu 
                245                 250                 255     


Phe His Ser His Glu Phe His Ser His Glu Asp Met Leu Val Val Asp 
            260                 265                 270         


Pro Lys Ser Lys Glu Glu Asp Lys His Leu Lys Phe Arg Ile Ser His 
        275                 280                 285             


Glu Leu Asp Ser Ala Ser Ser Glu Val Asn 
    290                 295             


<210>  2063
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  2063

Ala Pro Asp Gln Asp Glu Ile Gln Arg Leu Pro Gly Leu Ala Lys Gln 
1               5                   10                  15      


Pro Ser Phe Arg Gln Tyr Ser Gly Tyr Leu Lys Gly Ser Gly Ser Lys 
            20                  25                  30          


His Leu His Tyr Trp Phe Val Glu Ser Gln Lys Asp Pro Glu Asn Ser 
        35                  40                  45              


Pro Val Val Leu Trp Leu Asn Gly Gly Pro Gly Cys Ser Ser Leu Asp 
    50                  55                  60                  


Gly Leu Leu Thr Glu His Gly Pro Phe Leu Val Gln Pro Asp Gly Val 
65                  70                  75                  80  


Thr Leu Glu Tyr Asn Pro Tyr Ser Trp Asn Leu Ile Ala Asn Val Leu 
                85                  90                  95      


Tyr Leu Glu Ser Pro Ala Gly Val Gly Phe Ser Tyr Ser Asp Asp Lys 
            100                 105                 110         


Phe Tyr Ala Thr Asn Asp Thr Glu Val Ala Gln Ser Asn Phe Glu Ala 
        115                 120                 125             


Leu Gln Asp Phe Phe Arg Leu Phe Pro Glu Tyr Lys Asn Asn Lys Leu 
    130                 135                 140                 


Phe Leu Thr Gly Glu Ser Tyr Ala Gly Ile Tyr Ile Pro Thr Leu Ala 
145                 150                 155                 160 


Val Leu Val Met Gln Asp Pro Ser Met Asn Leu Gln Gly Leu Ala Val 
                165                 170                 175     


Gly Asn Gly Leu Ser Ser Tyr Glu Gln Asn Asp Asn Ser Leu Val Tyr 
            180                 185                 190         


Phe Ala Tyr Tyr His Gly Leu Leu Gly Asn Arg Leu Trp Ser Ser Leu 
        195                 200                 205             


Gln Thr His Cys Cys Ser Gln Asn Lys Cys Asn Phe Tyr Asp Asn Lys 
    210                 215                 220                 


Asp Leu Glu Cys Val Thr Asn Leu Gln Glu Val Ala Arg Ile Val Gly 
225                 230                 235                 240 


Asn Ser Gly Leu Asn Ile Tyr Asn Leu Tyr Ala Pro Cys Ala Gly Gly 
                245                 250                 255     


Val Pro Ser His Phe Arg Tyr Glu Lys Asp Thr Val Val Val Gln Asp 
            260                 265                 270         


Leu Gly Asn Ile Phe Thr Arg Leu Pro Leu Lys Arg Met Trp His Gln 
        275                 280                 285             


Ala Leu Leu Arg Ser Gly Asp Lys Val Arg Met Asp Pro Pro Cys Thr 
    290                 295                 300                 


Asn Thr Thr Ala Ala Ser Thr Tyr Leu Asn Asn Pro Tyr Val Arg Lys 
305                 310                 315                 320 


Ala Leu Asn Ile Pro Glu Gln Leu Pro Gln Trp Asp Met Cys Asn Phe 
                325                 330                 335     


Leu Val Asn Leu Gln Tyr Arg Arg Leu Tyr Arg Ser Met Asn Ser Gln 
            340                 345                 350         


Tyr Leu Lys Leu Leu Ser Ser Gln Lys Tyr Gln Ile Leu Leu Tyr Asn 
        355                 360                 365             


Gly Asp Val Asp Met Ala Cys Asn Phe Met Gly Asp Glu Trp Phe Val 
    370                 375                 380                 


Asp Ser Leu Asn Gln Lys Met Glu Val Gln Arg Arg Pro Trp Leu Val 
385                 390                 395                 400 


Lys Tyr Gly Asp Ser Gly Glu Gln Ile Ala Gly Phe Val Lys Glu Phe 
                405                 410                 415     


Ser His Ile Ala Phe Leu Thr Ile Lys Gly Ala Gly His Met Val Pro 
            420                 425                 430         


Thr Asp Lys Pro Leu Ala Ala Phe Thr Met Phe Ser Arg Phe Leu Asn 
        435                 440                 445             


Lys Gln Pro Tyr 
    450         


<210>  2064
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  2064

Leu Pro Val Asn Ser Pro Met Asn Lys Gly Asp Thr Glu Val Met Lys 
1               5                   10                  15      


Cys Ile Val Glu Val Ile Ser Asp Thr Leu Ser Lys Pro Ser Pro Met 
            20                  25                  30          


Pro Val Ser Gln Glu Cys Phe Glu Thr Leu Arg Gly Asp Glu Arg Ile 
        35                  40                  45              


Leu Ser Ile Leu Arg His Gln Asn Leu Leu Lys Glu Leu Gln Asp Leu 
    50                  55                  60                  


Ala Leu Gln Gly Ala Lys Glu Arg Ala His Gln Gln Lys Lys His Ser 
65                  70                  75                  80  


Gly Phe Glu Asp Glu Leu Ser Glu Val Leu Glu Asn Gln Ser Ser Gln 
                85                  90                  95      


Ala Glu Leu Lys Glu Ala Val Glu Glu Pro Ser Ser Lys Asp Val Met 
            100                 105                 110         


Glu 
    


<210>  2065
<211>  484
<212>  PRT
<213>  Homo Sapiens

<400>  2065

Ile Ile Pro Val Glu Glu Glu Asn Pro Asp Phe Trp Asn Arg Glu Ala 
1               5                   10                  15      


Ala Glu Ala Leu Gly Ala Ala Lys Lys Leu Gln Pro Ala Gln Thr Ala 
            20                  25                  30          


Ala Lys Asn Leu Ile Ile Phe Leu Gly Asp Gly Met Gly Val Ser Thr 
        35                  40                  45              


Val Thr Ala Ala Arg Ile Leu Lys Gly Gln Lys Lys Asp Lys Leu Gly 
    50                  55                  60                  


Pro Glu Leu Pro Leu Ala Met Asp Arg Phe Pro Tyr Val Ala Leu Ser 
65                  70                  75                  80  


Lys Thr Tyr Asn Val Asp Lys His Val Pro Asp Ser Gly Ala Thr Ala 
                85                  90                  95      


Thr Ala Tyr Leu Cys Gly Val Lys Gly Asn Phe Gln Thr Ile Gly Leu 
            100                 105                 110         


Ser Ala Ala Ala Arg Phe Asn Gln Cys Asn Thr Thr Arg Gly Asn Glu 
        115                 120                 125             


Val Ile Ser Val Met Asn Arg Ala Lys Lys Ala Gly Lys Ser Val Gly 
    130                 135                 140                 


Val Val Thr Thr Thr Arg Val Gln His Ala Ser Pro Ala Gly Thr Tyr 
145                 150                 155                 160 


Ala His Thr Val Asn Arg Asn Trp Tyr Ser Asp Ala Asp Val Pro Ala 
                165                 170                 175     


Ser Ala Arg Gln Glu Gly Cys Gln Asp Ile Ala Thr Gln Leu Ile Ser 
            180                 185                 190         


Asn Met Asp Ile Asp Val Ile Leu Gly Gly Gly Arg Lys Tyr Met Phe 
        195                 200                 205             


Arg Met Gly Thr Pro Asp Pro Glu Tyr Pro Asp Asp Tyr Ser Gln Gly 
    210                 215                 220                 


Gly Thr Arg Leu Asp Gly Lys Asn Leu Val Gln Glu Trp Leu Ala Lys 
225                 230                 235                 240 


Arg Gln Gly Ala Arg Tyr Val Trp Asn Arg Thr Glu Leu Met Gln Ala 
                245                 250                 255     


Ser Leu Asp Pro Ser Val Thr His Leu Met Gly Leu Phe Glu Pro Gly 
            260                 265                 270         


Asp Met Lys Tyr Glu Ile His Arg Asp Ser Thr Leu Asp Pro Ser Leu 
        275                 280                 285             


Met Glu Met Thr Glu Ala Ala Leu Arg Leu Leu Ser Arg Asn Pro Arg 
    290                 295                 300                 


Gly Phe Phe Leu Phe Val Glu Gly Gly Arg Ile Asp His Gly His His 
305                 310                 315                 320 


Glu Ser Arg Ala Tyr Arg Ala Leu Thr Glu Thr Ile Met Phe Asp Asp 
                325                 330                 335     


Ala Ile Glu Arg Ala Gly Gln Leu Thr Ser Glu Glu Asp Thr Leu Ser 
            340                 345                 350         


Leu Val Thr Ala Asp His Ser His Val Phe Ser Phe Gly Gly Tyr Pro 
        355                 360                 365             


Leu Arg Gly Ser Ser Ile Phe Gly Leu Ala Pro Gly Lys Ala Arg Asp 
    370                 375                 380                 


Arg Lys Ala Tyr Thr Val Leu Leu Tyr Gly Asn Gly Pro Gly Tyr Val 
385                 390                 395                 400 


Leu Lys Asp Gly Ala Arg Pro Asp Val Thr Glu Ser Glu Ser Gly Ser 
                405                 410                 415     


Pro Glu Tyr Arg Gln Gln Ser Ala Val Pro Leu Asp Glu Glu Thr His 
            420                 425                 430         


Ala Gly Glu Asp Val Ala Val Phe Ala Arg Gly Pro Gln Ala His Leu 
        435                 440                 445             


Val His Gly Val Gln Glu Gln Thr Phe Ile Ala His Val Met Ala Phe 
    450                 455                 460                 


Ala Ala Cys Leu Glu Pro Tyr Thr Ala Cys Asp Leu Ala Pro Pro Ala 
465                 470                 475                 480 


Gly Thr Thr Asp 
                


<210>  2066
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  2066

Phe Ala Arg Ala Glu Ala Glu Glu Asp Gly Asp Leu Gln Cys Leu Cys 
1               5                   10                  15      


Val Lys Thr Thr Ser Gln Val Arg Pro Arg His Ile Thr Ser Leu Glu 
            20                  25                  30          


Val Ile Lys Ala Gly Pro His Cys Pro Thr Ala Gln Leu Ile Ala Thr 
        35                  40                  45              


Leu Lys Asn Gly Arg Lys Ile Cys Leu Asp Leu Gln Ala Leu Leu Tyr 
    50                  55                  60                  


Lys Lys Ile Ile Lys Glu His Leu Glu Ser 
65                  70                  


<210>  2067
<211>  427
<212>  PRT
<213>  Homo Sapiens

<400>  2067

Asp Gln Thr Val Ser Asp Asn Glu Leu Gln Glu Met Ser Asn Gln Gly 
1               5                   10                  15      


Ser Lys Tyr Val Asn Lys Glu Ile Gln Asn Ala Val Asn Gly Val Lys 
            20                  25                  30          


Gln Ile Lys Thr Leu Ile Glu Lys Thr Asn Glu Glu Arg Lys Thr Leu 
        35                  40                  45              


Leu Ser Asn Leu Glu Glu Ala Lys Lys Lys Lys Glu Asp Ala Leu Asn 
    50                  55                  60                  


Glu Thr Arg Glu Ser Glu Thr Lys Leu Lys Glu Leu Pro Gly Val Cys 
65                  70                  75                  80  


Asn Glu Thr Met Met Ala Leu Trp Glu Glu Cys Lys Pro Cys Leu Lys 
                85                  90                  95      


Gln Thr Cys Met Lys Phe Tyr Ala Arg Val Cys Arg Ser Gly Ser Gly 
            100                 105                 110         


Leu Val Gly Arg Gln Leu Glu Glu Phe Leu Asn Gln Ser Ser Pro Phe 
        115                 120                 125             


Tyr Phe Trp Met Asn Gly Asp Arg Ile Asp Ser Leu Leu Glu Asn Asp 
    130                 135                 140                 


Arg Gln Gln Thr His Met Leu Asp Val Met Gln Asp His Phe Ser Arg 
145                 150                 155                 160 


Ala Ser Ser Ile Ile Asp Glu Leu Phe Gln Asp Arg Phe Phe Thr Arg 
                165                 170                 175     


Glu Pro Gln Asp Thr Tyr His Tyr Leu Pro Phe Ser Leu Pro His Arg 
            180                 185                 190         


Arg Pro His Phe Phe Phe Pro Lys Ser Arg Ile Val Arg Ser Leu Met 
        195                 200                 205             


Pro Phe Ser Pro Tyr Glu Pro Leu Asn Phe His Ala Met Phe Gln Pro 
    210                 215                 220                 


Phe Leu Glu Met Ile His Glu Ala Gln Gln Ala Met Asp Ile His Phe 
225                 230                 235                 240 


His Ser Pro Ala Phe Gln His Pro Pro Thr Glu Phe Ile Arg Glu Gly 
                245                 250                 255     


Asp Asp Asp Arg Thr Val Cys Arg Glu Ile Arg His Asn Ser Thr Gly 
            260                 265                 270         


Cys Leu Arg Met Lys Asp Gln Cys Asp Lys Cys Arg Glu Ile Leu Ser 
        275                 280                 285             


Val Asp Cys Ser Thr Asn Asn Pro Ser Gln Ala Lys Leu Arg Arg Glu 
    290                 295                 300                 


Leu Asp Glu Ser Leu Gln Val Ala Glu Arg Leu Thr Arg Lys Tyr Asn 
305                 310                 315                 320 


Glu Leu Leu Lys Ser Tyr Gln Trp Lys Met Leu Asn Thr Ser Ser Leu 
                325                 330                 335     


Leu Glu Gln Leu Asn Glu Gln Phe Asn Trp Val Ser Arg Leu Ala Asn 
            340                 345                 350         


Leu Thr Gln Gly Glu Asp Gln Tyr Tyr Leu Arg Val Thr Thr Val Ala 
        355                 360                 365             


Ser His Thr Ser Asp Ser Asp Val Pro Ser Gly Val Thr Glu Val Val 
    370                 375                 380                 


Val Lys Leu Phe Asp Ser Asp Pro Ile Thr Val Thr Val Pro Val Glu 
385                 390                 395                 400 


Val Ser Arg Lys Asn Pro Lys Phe Met Glu Thr Val Ala Glu Lys Ala 
                405                 410                 415     


Leu Gln Glu Tyr Arg Lys Lys His Arg Glu Glu 
            420                 425         


<210>  2068
<211>  636
<212>  PRT
<213>  Homo Sapiens

<400>  2068

Glu Glu Glu Asp Lys Lys Glu Asp Val Gly Thr Val Val Gly Ile Asp 
1               5                   10                  15      


Leu Gly Thr Thr Tyr Ser Cys Val Gly Val Phe Lys Asn Gly Arg Val 
            20                  25                  30          


Glu Ile Ile Ala Asn Asp Gln Gly Asn Arg Ile Thr Pro Ser Tyr Val 
        35                  40                  45              


Ala Phe Thr Pro Glu Gly Glu Arg Leu Ile Gly Asp Ala Ala Lys Asn 
    50                  55                  60                  


Gln Leu Thr Ser Asn Pro Glu Asn Thr Val Phe Asp Ala Lys Arg Leu 
65                  70                  75                  80  


Ile Gly Arg Thr Trp Asn Asp Pro Ser Val Gln Gln Asp Ile Lys Phe 
                85                  90                  95      


Leu Pro Phe Lys Val Val Glu Lys Lys Thr Lys Pro Tyr Ile Gln Val 
            100                 105                 110         


Asp Ile Gly Gly Gly Gln Thr Lys Thr Phe Ala Pro Glu Glu Ile Ser 
        115                 120                 125             


Ala Met Val Leu Thr Lys Met Lys Glu Thr Ala Glu Ala Tyr Leu Gly 
    130                 135                 140                 


Lys Lys Val Thr His Ala Val Val Thr Val Pro Ala Tyr Phe Asn Asp 
145                 150                 155                 160 


Ala Gln Arg Gln Ala Thr Lys Asp Ala Gly Thr Ile Ala Gly Leu Asn 
                165                 170                 175     


Val Met Arg Ile Ile Asn Glu Pro Thr Ala Ala Ala Ile Ala Tyr Gly 
            180                 185                 190         


Leu Asp Lys Arg Glu Gly Glu Lys Asn Ile Leu Val Phe Asp Leu Gly 
        195                 200                 205             


Gly Gly Thr Phe Asp Val Ser Leu Leu Thr Ile Asp Asn Gly Val Phe 
    210                 215                 220                 


Glu Val Val Ala Thr Asn Gly Asp Thr His Leu Gly Gly Glu Asp Phe 
225                 230                 235                 240 


Asp Gln Arg Val Met Glu His Phe Ile Lys Leu Tyr Lys Lys Lys Thr 
                245                 250                 255     


Gly Lys Asp Val Arg Lys Asp Asn Arg Ala Val Gln Lys Leu Arg Arg 
            260                 265                 270         


Glu Val Glu Lys Ala Lys Arg Ala Leu Ser Ser Gln His Gln Ala Arg 
        275                 280                 285             


Ile Glu Ile Glu Ser Phe Tyr Glu Gly Glu Asp Phe Ser Glu Thr Leu 
    290                 295                 300                 


Thr Arg Ala Lys Phe Glu Glu Leu Asn Met Asp Leu Phe Arg Ser Thr 
305                 310                 315                 320 


Met Lys Pro Val Gln Lys Val Leu Glu Asp Ser Asp Leu Lys Lys Ser 
                325                 330                 335     


Asp Ile Asp Glu Ile Val Leu Val Gly Gly Ser Thr Arg Ile Pro Lys 
            340                 345                 350         


Ile Gln Gln Leu Val Lys Glu Phe Phe Asn Gly Lys Glu Pro Ser Arg 
        355                 360                 365             


Gly Ile Asn Pro Asp Glu Ala Val Ala Tyr Gly Ala Ala Val Gln Ala 
    370                 375                 380                 


Gly Val Leu Ser Gly Asp Gln Asp Thr Gly Asp Leu Val Leu Leu Asp 
385                 390                 395                 400 


Val Cys Pro Leu Thr Leu Gly Ile Glu Thr Val Gly Gly Val Met Thr 
                405                 410                 415     


Lys Leu Ile Pro Arg Asn Thr Val Val Pro Thr Lys Lys Ser Gln Ile 
            420                 425                 430         


Phe Ser Thr Ala Ser Asp Asn Gln Pro Thr Val Thr Ile Lys Val Tyr 
        435                 440                 445             


Glu Gly Glu Arg Pro Leu Thr Lys Asp Asn His Leu Leu Gly Thr Phe 
    450                 455                 460                 


Asp Leu Thr Gly Ile Pro Pro Ala Pro Arg Gly Val Pro Gln Ile Glu 
465                 470                 475                 480 


Val Thr Phe Glu Ile Asp Val Asn Gly Ile Leu Arg Val Thr Ala Glu 
                485                 490                 495     


Asp Lys Gly Thr Gly Asn Lys Asn Lys Ile Thr Ile Thr Asn Asp Gln 
            500                 505                 510         


Asn Arg Leu Thr Pro Glu Glu Ile Glu Arg Met Val Asn Asp Ala Glu 
        515                 520                 525             


Lys Phe Ala Glu Glu Asp Lys Lys Leu Lys Glu Arg Ile Asp Thr Arg 
    530                 535                 540                 


Asn Glu Leu Glu Ser Tyr Ala Tyr Ser Leu Lys Asn Gln Ile Gly Asp 
545                 550                 555                 560 


Lys Glu Lys Leu Gly Gly Lys Leu Ser Ser Glu Asp Lys Glu Thr Met 
                565                 570                 575     


Glu Lys Ala Val Glu Glu Lys Ile Glu Trp Leu Glu Ser His Gln Asp 
            580                 585                 590         


Ala Asp Ile Glu Asp Phe Lys Ala Lys Lys Lys Glu Leu Glu Glu Ile 
        595                 600                 605             


Val Gln Pro Ile Ile Ser Lys Leu Tyr Gly Ser Ala Gly Pro Pro Pro 
    610                 615                 620                 


Thr Gly Glu Glu Asp Thr Ala Glu Lys Asp Glu Leu 
625                 630                 635     


<210>  2069
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  2069

Leu Gly Gln Ser Leu Lys Pro Glu Pro Phe Gly Arg Arg Ala Gln Ala 
1               5                   10                  15      


Val Glu Thr Asn Lys Thr Leu His Glu Met Lys Thr Arg Phe Leu Leu 
            20                  25                  30          


Phe Gly Glu Thr Asn Gln Gly Cys Gln Ile Arg Ile Asn His Pro Asp 
        35                  40                  45              


Thr Leu Gln Glu Cys Gly Phe Asn Ser Ser Leu Pro Leu Val Met Ile 
    50                  55                  60                  


Ile His Gly Trp Ser Val Asp Gly Val Leu Glu Asn Trp Ile Trp Gln 
65                  70                  75                  80  


Met Val Ala Ala Leu Lys Ser Gln Pro Ala Gln Pro Val Asn Val Gly 
                85                  90                  95      


Leu Val Asp Trp Ile Thr Leu Ala His Asp His Tyr Thr Ile Ala Val 
            100                 105                 110         


Arg Asn Thr Arg Leu Val Gly Lys Glu Val Ala Ala Leu Leu Arg Trp 
        115                 120                 125             


Leu Glu Glu Ser Val Gln Leu Ser Arg Ser His Val His Leu Ile Gly 
    130                 135                 140                 


Tyr Ser Leu Gly Ala His Val Ser Gly Phe Ala Gly Ser Ser Ile Gly 
145                 150                 155                 160 


Gly Thr His Lys Ile Gly Arg Ile Thr Gly Leu Asp Ala Ala Gly Pro 
                165                 170                 175     


Leu Phe Glu Gly Ser Ala Pro Ser Asn Arg Leu Ser Pro Asp Asp Ala 
            180                 185                 190         


Asn Phe Val Asp Ala Ile His Thr Phe Thr Arg Glu His Met Gly Leu 
        195                 200                 205             


Ser Val Gly Ile Lys Gln Pro Ile Gly His Tyr Asp Phe Tyr Pro Asn 
    210                 215                 220                 


Gly Gly Ser Phe Gln Pro Gly Cys His Phe Leu Glu Leu Tyr Arg His 
225                 230                 235                 240 


Ile Ala Gln His Gly Phe Asn Ala Ile Thr Gln Thr Ile Lys Cys Ser 
                245                 250                 255     


His Glu Arg Ser Val His Leu Phe Ile Asp Ser Leu Leu His Ala Gly 
            260                 265                 270         


Thr Gln Ser Met Ala Tyr Pro Cys Gly Asp Met Asn Ser Phe Ser Gln 
        275                 280                 285             


Gly Leu Cys Leu Ser Cys Lys Lys Gly Arg Cys Asn Thr Leu Gly Tyr 
    290                 295                 300                 


His Val Arg Gln Glu Pro Arg Ser Lys Ser Lys Arg Leu Phe Leu Val 
305                 310                 315                 320 


Thr Arg Ala Gln Ser Pro Phe Lys Val Tyr His Tyr Gln Leu Lys Ile 
                325                 330                 335     


Gln Phe Ile Asn Gln Thr Glu Thr Pro Ile Gln Thr Thr Phe Thr Met 
            340                 345                 350         


Ser Leu Leu Gly Thr Lys Glu Lys Met Gln Lys Ile Pro Ile Thr Leu 
        355                 360                 365             


Gly Lys Gly Ile Ala Ser Asn Lys Thr Tyr Ser Phe Leu Ile Thr Leu 
    370                 375                 380                 


Asp Val Asp Ile Gly Glu Leu Ile Met Ile Lys Phe Lys Trp Glu Asn 
385                 390                 395                 400 


Ser Ala Val Trp Ala Asn Val Trp Asp Thr Val Gln Thr Ile Ile Pro 
                405                 410                 415     


Trp Ser Thr Gly Pro Arg His Ser Gly Leu Val Leu Lys Thr Ile Arg 
            420                 425                 430         


Val Lys Ala Gly Glu Thr Gln Gln Arg Met Thr Phe Cys Ser Glu Asn 
        435                 440                 445             


Thr Asp Asp Leu Leu Leu Arg Pro Thr Gln Glu Lys Ile Phe Val Lys 
    450                 455                 460                 


Cys Glu Ile Lys Ser Lys Thr Ser Lys Arg Lys Ile Arg 
465                 470                 475         


<210>  2070
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  2070

Ser Glu Ala Glu Gly Arg Leu Arg Glu Lys Leu Phe Ser Gly Tyr Asp 
1               5                   10                  15      


Ser Ser Val Arg Pro Ala Arg Glu Val Gly Asp Arg Val Arg Val Ser 
            20                  25                  30          


Val Gly Leu Ile Leu Ala Gln Leu Ile Ser Leu Asn Glu Lys Asp Glu 
        35                  40                  45              


Glu Met Ser Thr Lys Val Tyr Leu Asp Leu Glu Trp Thr Asp Tyr Arg 
    50                  55                  60                  


Leu Ser Trp Asp Pro Ala Glu His Asp Gly Ile Asp Ser Leu Arg Ile 
65                  70                  75                  80  


Thr Ala Glu Ser Val Trp Leu Pro Asp Val Val Leu Leu Asn Asn Asn 
                85                  90                  95      


Asp Gly Asn Phe Asp Val Ala Leu Asp Ile Ser Val Val Val Ser Ser 
            100                 105                 110         


Asp Gly Ser Val Arg Trp Gln Pro Pro Gly Ile Tyr Arg Ser Ser Cys 
        115                 120                 125             


Ser Ile Gln Val Thr Tyr Phe Pro Phe Asp Trp Gln Asn Cys Thr Met 
    130                 135                 140                 


Val Phe Ser Ser Tyr Ser Tyr Asp Ser Ser Glu Val Ser Leu Gln Thr 
145                 150                 155                 160 


Gly Leu Gly Pro Asp Gly Gln Gly His Gln Glu Ile His Ile His Glu 
                165                 170                 175     


Gly Thr Phe Ile Glu Asn Gly Gln Trp Glu Ile Ile His Lys Pro Ser 
            180                 185                 190         


Arg Leu Ile Gln Pro Pro Gly Asp Pro Arg Gly Gly Arg Glu Gly Gln 
        195                 200                 205             


Arg Gln Glu Val Ile Phe Tyr Leu Ile Ile Arg Arg Lys 
    210                 215                 220     


<210>  2071
<211>  476
<212>  PRT
<213>  Homo Sapiens

<400>  2071

Cys Ser Lys Gly Thr Ser His Glu Ala Gly Ile Val Cys Arg Ile Thr 
1               5                   10                  15      


Lys Pro Ala Leu Leu Val Leu Asn His Glu Thr Ala Lys Val Ile Gln 
            20                  25                  30          


Thr Ala Phe Gln Arg Ala Ser Tyr Pro Asp Ile Thr Gly Glu Lys Ala 
        35                  40                  45              


Met Met Leu Leu Gly Gln Val Lys Tyr Gly Leu His Asn Ile Gln Ile 
    50                  55                  60                  


Ser His Leu Ser Ile Ala Ser Ser Gln Val Glu Leu Val Glu Ala Lys 
65                  70                  75                  80  


Ser Ile Asp Val Ser Ile Gln Asn Val Ser Val Val Phe Lys Gly Thr 
                85                  90                  95      


Leu Lys Tyr Gly Tyr Thr Thr Ala Trp Trp Leu Gly Ile Asp Gln Ser 
            100                 105                 110         


Ile Asp Phe Glu Ile Asp Ser Ala Ile Asp Leu Gln Ile Asn Thr Gln 
        115                 120                 125             


Leu Thr Cys Asp Ser Gly Arg Val Arg Thr Asp Ala Pro Asp Cys Tyr 
    130                 135                 140                 


Leu Ser Phe His Lys Leu Leu Leu His Leu Gln Gly Glu Arg Glu Pro 
145                 150                 155                 160 


Gly Trp Ile Lys Gln Leu Phe Thr Asn Phe Ile Ser Phe Thr Leu Lys 
                165                 170                 175     


Leu Val Leu Lys Gly Gln Ile Cys Lys Glu Ile Asn Val Ile Ser Asn 
            180                 185                 190         


Ile Met Ala Asp Phe Val Gln Thr Arg Ala Ala Ser Ile Leu Ser Asp 
        195                 200                 205             


Gly Asp Ile Gly Val Asp Ile Ser Leu Thr Gly Asp Pro Val Ile Thr 
    210                 215                 220                 


Ala Ser Tyr Leu Glu Ser His His Lys Gly His Phe Ile Tyr Lys Asn 
225                 230                 235                 240 


Val Ser Glu Asp Leu Pro Leu Pro Thr Phe Ser Pro Thr Leu Leu Gly 
                245                 250                 255     


Asp Ser Arg Met Leu Tyr Phe Trp Phe Ser Glu Arg Val Phe His Ser 
            260                 265                 270         


Leu Ala Lys Val Ala Phe Gln Asp Gly Arg Leu Met Leu Ser Leu Met 
        275                 280                 285             


Gly Asp Glu Phe Lys Ala Val Leu Glu Thr Trp Gly Phe Asn Thr Asn 
    290                 295                 300                 


Gln Glu Ile Phe Gln Glu Val Val Gly Gly Phe Pro Ser Gln Ala Gln 
305                 310                 315                 320 


Val Thr Val His Cys Leu Lys Met Pro Lys Ile Ser Cys Gln Asn Lys 
                325                 330                 335     


Gly Val Val Val Asn Ser Ser Val Met Val Lys Phe Leu Phe Pro Arg 
            340                 345                 350         


Pro Asp Gln Gln His Ser Val Ala Tyr Thr Phe Glu Glu Asp Ile Val 
        355                 360                 365             


Thr Thr Val Gln Ala Ser Tyr Ser Lys Lys Lys Leu Phe Leu Ser Leu 
    370                 375                 380                 


Leu Asp Phe Gln Ile Thr Pro Lys Thr Val Ser Asn Leu Thr Glu Ser 
385                 390                 395                 400 


Ser Ser Glu Ser Ile Gln Ser Phe Leu Gln Ser Met Ile Thr Ala Val 
                405                 410                 415     


Gly Ile Pro Glu Val Met Ser Arg Leu Glu Val Val Phe Thr Ala Leu 
            420                 425                 430         


Met Asn Ser Lys Gly Val Ser Leu Phe Asp Ile Ile Asn Pro Glu Ile 
        435                 440                 445             


Ile Thr Arg Asp Gly Phe Leu Leu Leu Gln Met Asp Phe Gly Phe Pro 
    450                 455                 460                 


Glu His Leu Leu Val Asp Phe Leu Gln Ser Leu Ser 
465                 470                 475     


<210>  2072
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  2072

Glu Ile Cys Pro Ser Phe Gln Arg Val Ile Glu Thr Leu Leu Met Asp 
1               5                   10                  15      


Thr Pro Ser Ser Tyr Glu Ala Ala Met Glu Leu Phe Ser Pro Asp Gln 
            20                  25                  30          


Asp Met Arg Glu Ala Gly Ala Gln Leu Lys Lys Leu Val Asp Thr Leu 
        35                  40                  45              


Pro Gln Lys Pro Arg Glu Ser Ile Ile Lys Leu Met Glu Lys Ile Ala 
    50                  55                  60                  


Gln Ser Ser Leu Cys Asn 
65                  70  


<210>  2073
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  2073

Gln Pro Val Leu His Gln Pro Pro Ala Met Ser Ser Ala Leu Gly Thr 
1               5                   10                  15      


Thr Ile Arg Leu Thr Cys Thr Leu Arg Asn Asp His Asp Ile Gly Val 
            20                  25                  30          


Tyr Ser Val Tyr Trp Tyr Gln Gln Arg Pro Gly His Pro Pro Arg Phe 
        35                  40                  45              


Leu Leu Arg Tyr Phe Ser Gln Ser Asp Lys Ser Gln Gly Pro Gln Val 
    50                  55                  60                  


Pro Pro Arg Phe Ser Gly Ser Lys Asp Val Ala Arg Asn Arg Gly Tyr 
65                  70                  75                  80  


Leu Ser Ile Ser Glu Leu Gln Pro Glu Asp Glu Ala Met Tyr Tyr Cys 
                85                  90                  95      


Ala Met Gly Ala Arg Ser Ser Glu Lys Glu Glu Arg Glu Arg Glu Trp 
            100                 105                 110         


Glu Glu Glu Met Glu Pro Thr Ala Ala Arg Thr Arg Val Pro 
        115                 120                 125     


<210>  2074
<211>  999
<212>  PRT
<213>  Homo Sapiens

<400>  2074

Gln Gln Gln Glu Val Ile Ser Pro Asp Thr Thr Glu Arg Asn Asn Asn 
1               5                   10                  15      


Cys Pro Glu Lys Thr Asp Cys Pro Ile His Val Tyr Phe Val Leu Asp 
            20                  25                  30          


Thr Ser Glu Ser Val Thr Met Gln Ser Pro Thr Asp Ile Leu Leu Phe 
        35                  40                  45              


His Met Lys Gln Phe Val Pro Gln Phe Ile Ser Gln Leu Gln Asn Glu 
    50                  55                  60                  


Phe Tyr Leu Asp Gln Val Ala Leu Ser Trp Arg Tyr Gly Gly Leu His 
65                  70                  75                  80  


Phe Ser Asp Gln Val Glu Val Phe Ser Pro Pro Gly Ser Asp Arg Ala 
                85                  90                  95      


Ser Phe Ile Lys Asn Leu Gln Gly Ile Ser Ser Phe Arg Arg Gly Thr 
            100                 105                 110         


Phe Thr Asp Cys Ala Leu Ala Asn Met Thr Glu Gln Ile Arg Gln Asp 
        115                 120                 125             


Arg Ser Lys Gly Thr Val His Phe Ala Val Val Ile Thr Asp Gly His 
    130                 135                 140                 


Val Thr Gly Ser Pro Cys Gly Gly Ile Lys Leu Gln Ala Glu Arg Ala 
145                 150                 155                 160 


Arg Glu Glu Gly Ile Arg Leu Phe Ala Val Ala Pro Asn Gln Asn Leu 
                165                 170                 175     


Lys Glu Gln Gly Leu Arg Asp Ile Ala Ser Thr Pro His Glu Leu Tyr 
            180                 185                 190         


Arg Asn Asp Tyr Ala Thr Met Leu Pro Asp Ser Thr Glu Ile Asp Gln 
        195                 200                 205             


Asp Thr Ile Asn Arg Ile Ile Lys Val Met Lys His Glu Ala Tyr Gly 
    210                 215                 220                 


Glu Cys Tyr Lys Val Ser Cys Leu Glu Ile Pro Gly Pro Ser Gly Pro 
225                 230                 235                 240 


Lys Gly Tyr Arg Gly Gln Lys Gly Ala Lys Gly Asn Met Gly Glu Pro 
                245                 250                 255     


Gly Glu Pro Gly Gln Lys Gly Arg Gln Gly Asp Pro Gly Ile Glu Gly 
            260                 265                 270         


Pro Ile Gly Phe Pro Gly Pro Lys Gly Val Pro Gly Phe Lys Gly Glu 
        275                 280                 285             


Lys Gly Glu Phe Gly Ala Asp Gly Arg Lys Gly Ala Pro Gly Leu Ala 
    290                 295                 300                 


Gly Lys Asn Gly Thr Asp Gly Gln Lys Gly Lys Leu Gly Arg Ile Gly 
305                 310                 315                 320 


Pro Pro Gly Cys Lys Gly Asp Pro Gly Asn Arg Gly Pro Asp Gly Tyr 
                325                 330                 335     


Pro Gly Glu Ala Gly Ser Pro Gly Glu Arg Gly Asp Gln Gly Gly Lys 
            340                 345                 350         


Gly Asp Pro Gly Arg Pro Gly Arg Arg Gly Pro Pro Gly Glu Ile Gly 
        355                 360                 365             


Ala Lys Gly Ser Lys Gly Tyr Gln Gly Asn Asn Gly Ala Pro Gly Ser 
    370                 375                 380                 


Pro Gly Val Lys Gly Ala Lys Gly Gly Pro Gly Pro Arg Gly Pro Lys 
385                 390                 395                 400 


Gly Glu Pro Gly Arg Arg Gly Asp Pro Gly Thr Lys Gly Ser Pro Gly 
                405                 410                 415     


Ser Asp Gly Pro Lys Gly Glu Lys Gly Asp Pro Gly Pro Glu Gly Pro 
            420                 425                 430         


Arg Gly Leu Ala Gly Glu Val Gly Asn Lys Gly Ala Lys Gly Asp Arg 
        435                 440                 445             


Gly Leu Pro Gly Pro Arg Gly Pro Gln Gly Ala Leu Gly Glu Pro Gly 
    450                 455                 460                 


Lys Gln Gly Ser Arg Gly Asp Pro Gly Asp Ala Gly Pro Arg Gly Asp 
465                 470                 475                 480 


Ser Gly Gln Pro Gly Pro Lys Gly Asp Pro Gly Arg Pro Gly Phe Ser 
                485                 490                 495     


Tyr Pro Gly Pro Arg Gly Ala Pro Gly Glu Lys Gly Glu Pro Gly Pro 
            500                 505                 510         


Arg Gly Pro Glu Gly Gly Arg Gly Asp Phe Gly Leu Lys Gly Glu Pro 
        515                 520                 525             


Gly Arg Lys Gly Glu Lys Gly Glu Pro Ala Asp Pro Gly Pro Pro Gly 
    530                 535                 540                 


Glu Pro Gly Pro Arg Gly Pro Arg Gly Val Pro Gly Pro Glu Gly Glu 
545                 550                 555                 560 


Pro Gly Pro Pro Gly Asp Pro Gly Leu Thr Glu Cys Asp Val Met Thr 
                565                 570                 575     


Tyr Val Arg Glu Thr Cys Gly Cys Cys Asp Cys Glu Lys Arg Cys Gly 
            580                 585                 590         


Ala Leu Asp Val Val Phe Val Ile Asp Ser Ser Glu Ser Ile Gly Tyr 
        595                 600                 605             


Thr Asn Phe Thr Leu Glu Lys Asn Phe Val Ile Asn Val Val Asn Arg 
    610                 615                 620                 


Leu Gly Ala Ile Ala Lys Asp Pro Lys Ser Glu Thr Gly Thr Arg Val 
625                 630                 635                 640 


Gly Val Val Gln Tyr Ser His Glu Gly Thr Phe Glu Ala Ile Gln Leu 
                645                 650                 655     


Asp Asp Glu Arg Ile Asp Ser Leu Ser Ser Phe Lys Glu Ala Val Lys 
            660                 665                 670         


Asn Leu Glu Trp Ile Ala Gly Gly Thr Trp Thr Pro Ser Ala Leu Lys 
        675                 680                 685             


Phe Ala Tyr Asp Arg Leu Ile Lys Glu Ser Arg Arg Gln Lys Thr Arg 
    690                 695                 700                 


Val Phe Ala Val Val Ile Thr Asp Gly Arg His Asp Pro Arg Asp Asp 
705                 710                 715                 720 


Asp Leu Asn Leu Arg Ala Leu Cys Asp Arg Asp Val Thr Val Thr Ala 
                725                 730                 735     


Ile Gly Ile Gly Asp Met Phe His Glu Lys His Glu Ser Glu Asn Leu 
            740                 745                 750         


Tyr Ser Ile Ala Cys Asp Lys Pro Gln Gln Val Arg Asn Met Thr Leu 
        755                 760                 765             


Phe Ser Asp Leu Val Ala Glu Lys Phe Ile Asp Asp Met Glu Asp Val 
    770                 775                 780                 


Leu Cys Pro Asp Pro Gln Ile Val Cys Pro Asp Leu Pro Cys Gln Thr 
785                 790                 795                 800 


Glu Leu Ser Val Ala Gln Cys Thr Gln Arg Pro Val Asp Ile Val Phe 
                805                 810                 815     


Leu Leu Asp Gly Ser Glu Arg Leu Gly Glu Gln Asn Phe His Lys Ala 
            820                 825                 830         


Arg Arg Phe Val Glu Gln Val Ala Arg Arg Leu Thr Leu Ala Arg Arg 
        835                 840                 845             


Asp Asp Asp Pro Leu Asn Ala Arg Val Ala Leu Leu Gln Phe Gly Gly 
    850                 855                 860                 


Pro Gly Glu Gln Gln Val Ala Phe Pro Leu Ser His Asn Leu Thr Ala 
865                 870                 875                 880 


Ile His Glu Ala Leu Glu Thr Thr Gln Tyr Leu Asn Ser Phe Ser His 
                885                 890                 895     


Val Gly Ala Gly Val Val His Ala Ile Asn Ala Ile Val Arg Ser Pro 
            900                 905                 910         


Arg Gly Gly Ala Arg Arg His Ala Glu Leu Ser Phe Val Phe Leu Thr 
        915                 920                 925             


Asp Gly Val Thr Gly Asn Asp Ser Leu His Glu Ser Ala His Ser Met 
    930                 935                 940                 


Arg Lys Gln Asn Val Val Pro Thr Val Leu Ala Leu Gly Ser Asp Val 
945                 950                 955                 960 


Asp Met Asp Val Leu Thr Thr Leu Ser Leu Gly Asp Arg Ala Ala Val 
                965                 970                 975     


Phe His Glu Lys Asp Tyr Asp Ser Leu Ala Gln Pro Gly Phe Phe Asp 
            980                 985                 990         


Arg Phe Ile Arg Trp Ile Cys 
        995                 


<210>  2075
<211>  647
<212>  PRT
<213>  Homo Sapiens

<400>  2075

Asn Arg Arg Asn Tyr Tyr Ile Ala Ala Glu Glu Ile Ser Trp Asp Tyr 
1               5                   10                  15      


Ser Glu Phe Val Gln Arg Glu Thr Asp Ile Glu Asp Ser Asp Asp Ile 
            20                  25                  30          


Pro Glu Asp Thr Thr Tyr Lys Lys Val Val Phe Arg Lys Tyr Leu Asp 
        35                  40                  45              


Ser Thr Phe Thr Lys Arg Asp Pro Arg Gly Glu Tyr Glu Glu His Leu 
    50                  55                  60                  


Gly Ile Leu Gly Pro Ile Ile Arg Ala Glu Val Asp Asp Val Ile Gln 
65                  70                  75                  80  


Val Arg Phe Lys Asn Leu Ala Ser Arg Pro Tyr Ser Leu His Ala His 
                85                  90                  95      


Gly Leu Ser Tyr Glu Lys Ser Ser Glu Gly Lys Thr Tyr Glu Asp Asp 
            100                 105                 110         


Ser Pro Glu Trp Phe Lys Glu Asp Asn Ala Val Gln Pro Asn Ser Ser 
        115                 120                 125             


Tyr Thr Tyr Val Trp His Ala Thr Glu Arg Ser Gly Pro Glu Ser Pro 
    130                 135                 140                 


Gly Ser Ala Cys Arg Ala Trp Ala Tyr Tyr Ser Ala Val Asn Pro Glu 
145                 150                 155                 160 


Lys Asp Ile His Ser Gly Leu Ile Gly Pro Leu Leu Ile Cys Gln Lys 
                165                 170                 175     


Gly Ile Leu His Lys Asp Ser Asn Met Pro Met Asp Met Arg Glu Phe 
            180                 185                 190         


Val Leu Leu Phe Met Thr Phe Asp Glu Lys Lys Ser Trp Tyr Tyr Glu 
        195                 200                 205             


Lys Lys Ser Arg Ser Ser Trp Arg Leu Thr Ser Ser Glu Met Lys Lys 
    210                 215                 220                 


Ser His Glu Phe His Ala Ile Asn Gly Met Ile Tyr Ser Leu Pro Gly 
225                 230                 235                 240 


Leu Lys Met Tyr Glu Gln Glu Trp Val Arg Leu His Leu Leu Asn Ile 
                245                 250                 255     


Gly Gly Ser Gln Asp Ile His Val Val His Phe His Gly Gln Thr Leu 
            260                 265                 270         


Leu Glu Asn Gly Asn Lys Gln His Gln Leu Gly Val Trp Pro Leu Leu 
        275                 280                 285             


Pro Gly Ser Phe Lys Thr Leu Glu Met Lys Ala Ser Lys Pro Gly Trp 
    290                 295                 300                 


Trp Leu Leu Asn Thr Glu Val Gly Glu Asn Gln Arg Ala Gly Met Gln 
305                 310                 315                 320 


Thr Pro Phe Leu Ile Met Asp Arg Asp Cys Arg Met Pro Met Gly Leu 
                325                 330                 335     


Ser Thr Gly Ile Ile Ser Asp Ser Gln Ile Lys Ala Ser Glu Phe Leu 
            340                 345                 350         


Gly Tyr Trp Glu Pro Arg Leu Ala Arg Leu Asn Asn Gly Gly Ser Tyr 
        355                 360                 365             


Asn Ala Trp Ser Val Glu Lys Leu Ala Ala Glu Phe Ala Ser Lys Pro 
    370                 375                 380                 


Trp Ile Gln Val Asp Met Gln Lys Glu Val Ile Ile Thr Gly Ile Gln 
385                 390                 395                 400 


Thr Gln Gly Ala Lys His Tyr Leu Lys Ser Cys Tyr Thr Thr Glu Phe 
                405                 410                 415     


Tyr Val Ala Tyr Ser Ser Asn Gln Ile Asn Trp Gln Ile Phe Lys Gly 
            420                 425                 430         


Asn Ser Thr Arg Asn Val Met Tyr Phe Asn Gly Asn Ser Asp Ala Ser 
        435                 440                 445             


Thr Ile Lys Glu Asn Gln Phe Asp Pro Pro Ile Val Ala Arg Tyr Ile 
    450                 455                 460                 


Arg Ile Ser Pro Thr Arg Ala Tyr Asn Arg Pro Thr Leu Arg Leu Glu 
465                 470                 475                 480 


Leu Gln Gly Cys Glu Val Asn Gly Cys Ser Thr Pro Leu Gly Met Glu 
                485                 490                 495     


Asn Gly Lys Ile Glu Asn Lys Gln Ile Thr Ala Ser Ser Phe Lys Lys 
            500                 505                 510         


Ser Trp Trp Gly Asp Tyr Trp Glu Pro Phe Arg Ala Arg Leu Asn Ala 
        515                 520                 525             


Gln Gly Arg Val Asn Ala Trp Gln Ala Lys Ala Asn Asn Asn Lys Gln 
    530                 535                 540                 


Trp Leu Glu Ile Asp Leu Leu Lys Ile Lys Lys Ile Thr Ala Ile Ile 
545                 550                 555                 560 


Thr Gln Gly Cys Lys Ser Leu Ser Ser Glu Met Tyr Val Lys Ser Tyr 
                565                 570                 575     


Thr Ile His Tyr Ser Glu Gln Gly Val Glu Trp Lys Pro Tyr Arg Leu 
            580                 585                 590         


Lys Ser Ser Met Val Asp Lys Ile Phe Glu Gly Asn Thr Asn Thr Lys 
        595                 600                 605             


Gly His Val Lys Asn Phe Phe Asn Pro Pro Ile Ile Ser Arg Phe Ile 
    610                 615                 620                 


Arg Val Ile Pro Lys Thr Trp Asn Gln Ser Ile Ala Leu Arg Leu Glu 
625                 630                 635                 640 


Leu Phe Gly Cys Asp Ile Tyr 
                645         


<210>  2076
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  2076

Ala Val Ser Glu His Gln Leu Leu His Asp Lys Gly Lys Ser Ile Gln 
1               5                   10                  15      


Asp Leu Arg Arg Arg Phe Phe Leu His His Leu Ile Ala Glu Ile His 
            20                  25                  30          


Thr Ala Glu Ile Arg Ala Thr Ser Glu Val Ser Pro Asn Ser Lys Pro 
        35                  40                  45              


Ser Pro Asn Thr Lys Asn His Pro Val Arg Phe Gly Ser Asp Asp Glu 
    50                  55                  60                  


Gly Arg Tyr Leu Thr Gln Glu Thr Asn Lys Val Glu Thr Tyr Lys Glu 
65                  70                  75                  80  


Gln Pro Leu Lys Thr Pro Gly Lys Lys Lys Lys Gly Lys Pro Gly Lys 
                85                  90                  95      


Arg Lys Glu Gln Glu Lys Lys Lys Arg Arg Thr Arg Ser Ala Trp Leu 
            100                 105                 110         


Asp Ser Gly Val Thr Gly Ser Gly Leu Glu Gly Asp His Leu Ser Asp 
        115                 120                 125             


Thr Ser Thr Thr Ser Leu Glu Leu Asp Ser Arg 
    130                 135                 


<210>  2077
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2077

Ile Ile Gly Gly Asn Glu Val Thr Pro His Ser Arg Pro Tyr Met Val 
1               5                   10                  15      


Leu Leu Ser Leu Asp Arg Lys Thr Ile Cys Ala Gly Ala Leu Ile Ala 
            20                  25                  30          


Lys Asp Trp Val Leu Thr Ala Ala His Cys Asn Leu Asn Lys Arg Ser 
        35                  40                  45              


Gln Val Ile Leu Gly Ala His Ser Ile Thr Arg Glu Glu Pro Thr Lys 
    50                  55                  60                  


Gln Ile Met Leu Val Lys Lys Glu Phe Pro Tyr Pro Cys Tyr Asp Pro 
65                  70                  75                  80  


Ala Thr Arg Glu Gly Asp Leu Lys Leu Leu Gln Leu Thr Glu Lys Ala 
                85                  90                  95      


Lys Ile Asn Lys Tyr Val Thr Ile Leu His Leu Pro Lys Lys Gly Asp 
            100                 105                 110         


Asp Val Lys Pro Gly Thr Met Cys Gln Val Ala Gly Trp Gly Arg Thr 
        115                 120                 125             


His Asn Ser Ala Ser Trp Ser Asp Thr Leu Arg Glu Val Asn Ile Thr 
    130                 135                 140                 


Ile Ile Asp Arg Lys Val Cys Asn Asp Arg Asn His Tyr Asn Phe Asn 
145                 150                 155                 160 


Pro Val Ile Gly Met Asn Met Val Cys Ala Gly Ser Leu Arg Gly Gly 
                165                 170                 175     


Arg Asp Ser Cys Asn Gly Asp Ser Gly Ser Pro Leu Leu Cys Glu Gly 
            180                 185                 190         


Val Phe Arg Gly Val Thr Ser Phe Gly Leu Glu Asn Lys Cys Gly Asp 
        195                 200                 205             


Pro Arg Gly Pro Gly Val Tyr Ile Leu Leu Ser Lys Lys His Leu Asn 
    210                 215                 220                 


Trp Ile Ile Met Thr Ile Lys Gly Ala Val 
225                 230                 


<210>  2078
<211>  133
<212>  PRT
<213>  Homo Sapiens

<400>  2078

Arg Pro Pro Gln Phe Thr Arg Ala Gln Trp Phe Ala Ile Gln His Ile 
1               5                   10                  15      


Ser Leu Asn Pro Pro Arg Cys Thr Ile Ala Met Arg Ala Ile Asn Asn 
            20                  25                  30          


Tyr Arg Trp Arg Cys Lys Asn Gln Asn Thr Phe Leu Arg Thr Thr Phe 
        35                  40                  45              


Ala Asn Val Val Asn Val Cys Gly Asn Gln Ser Ile Arg Cys Pro His 
    50                  55                  60                  


Asn Arg Thr Leu Asn Asn Cys His Arg Ser Arg Phe Arg Val Pro Leu 
65                  70                  75                  80  


Leu His Cys Asp Leu Ile Asn Pro Gly Ala Gln Asn Ile Ser Asn Cys 
                85                  90                  95      


Arg Tyr Ala Asp Arg Pro Gly Arg Arg Phe Tyr Val Val Ala Cys Asp 
            100                 105                 110         


Asn Arg Asp Pro Arg Asp Ser Pro Arg Tyr Pro Val Val Pro Val His 
        115                 120                 125             


Leu Asp Thr Thr Ile 
    130             


<210>  2079
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  2079

Phe Val Pro Ile Phe Thr Tyr Gly Glu Leu Gln Arg Met Gln Glu Lys 
1               5                   10                  15      


Glu Arg Asn Lys Gly Gln Lys Lys Ser Leu Ser Val Trp Gln Arg Ser 
            20                  25                  30          


Gly Glu Glu Gly Pro Val Asp Pro Ala Glu Pro Ile Arg Glu Glu Glu 
        35                  40                  45              


Asn Glu Met Ile Lys Leu Thr Ala Pro Leu Glu Ile Gly Met Arg Met 
    50                  55                  60                  


Asn Ser Arg Gln Leu Glu Lys Tyr Pro Ala Thr Leu Glu Gly Leu Leu 
65                  70                  75                  80  


Ser Glu Met Leu Pro Gln His Ala Ala Lys 
                85                  90  


<210>  2080
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  2080

Asn Ala Pro Leu Val Asn Val Thr Leu Tyr Tyr Glu Ala Leu Cys Gly 
1               5                   10                  15      


Gly Cys Arg Ala Phe Leu Ile Arg Glu Leu Phe Pro Thr Trp Leu Leu 
            20                  25                  30          


Val Met Glu Ile Leu Asn Val Thr Leu Val Pro Tyr Gly Asn Ala Gln 
        35                  40                  45              


Glu Gln Asn Val Ser Gly Arg Trp Glu Phe Lys Cys Gln His Gly Glu 
    50                  55                  60                  


Glu Glu Cys Lys Phe Asn Lys Val Glu Ala Cys Val Leu Asp Glu Leu 
65                  70                  75                  80  


Asp Met Glu Leu Ala Phe Leu Thr Ile Val Cys Met Glu Glu Phe Glu 
                85                  90                  95      


Asp Met Glu Arg Ser Leu Pro Leu Cys Leu Gln Leu Tyr Ala Pro Gly 
            100                 105                 110         


Leu Ser Pro Asp Thr Ile Met Glu Cys Ala Met Gly Asp Arg Gly Met 
        115                 120                 125             


Gln Leu Met His Ala Asn Ala Gln Arg Thr Asp Ala Leu Gln Pro Pro 
    130                 135                 140                 


His Glu Tyr Val Pro Trp Val Thr Val Asn Gly Lys Pro Leu Glu Asp 
145                 150                 155                 160 


Gln Thr Gln Leu Leu Thr Leu Val Cys Gln Leu Tyr Gln Gly Lys 
                165                 170                 175 


<210>  2081
<211>  587
<212>  PRT
<213>  Homo Sapiens

<400>  2081

Gln Arg Asn Gln Leu Leu Gln Lys Glu Pro Asp Leu Arg Leu Glu Asn 
1               5                   10                  15      


Val Gln Lys Phe Pro Ser Pro Glu Met Ile Arg Ala Leu Glu Tyr Ile 
            20                  25                  30          


Glu Asn Leu Arg Gln Gln Ala His Lys Glu Glu Ser Ser Pro Asp Tyr 
        35                  40                  45              


Asn Pro Tyr Gln Gly Val Ser Val Pro Leu Gln Gln Lys Glu Asn Gly 
    50                  55                  60                  


Asp Glu Ser His Leu Pro Glu Arg Asp Ser Leu Ser Glu Glu Asp Trp 
65                  70                  75                  80  


Met Arg Ile Ile Leu Glu Ala Leu Arg Gln Ala Glu Asn Glu Pro Gln 
                85                  90                  95      


Ser Ala Pro Lys Glu Asn Lys Pro Tyr Ala Leu Asn Ser Glu Lys Asn 
            100                 105                 110         


Phe Pro Met Asp Met Ser Asp Asp Tyr Glu Thr Gln Gln Trp Pro Glu 
        115                 120                 125             


Arg Lys Leu Lys His Met Gln Phe Pro Pro Met Tyr Glu Glu Asn Ser 
    130                 135                 140                 


Arg Asp Asn Pro Phe Lys Arg Thr Asn Glu Ile Val Glu Glu Gln Tyr 
145                 150                 155                 160 


Thr Pro Gln Ser Leu Ala Thr Leu Glu Ser Val Phe Gln Glu Leu Gly 
                165                 170                 175     


Lys Leu Thr Gly Pro Asn Asn Gln Lys Arg Glu Arg Met Asp Glu Glu 
            180                 185                 190         


Gln Lys Leu Tyr Thr Asp Asp Glu Asp Asp Ile Tyr Lys Ala Asn Asn 
        195                 200                 205             


Ile Ala Tyr Glu Asp Val Val Gly Gly Glu Asp Trp Asn Pro Val Glu 
    210                 215                 220                 


Glu Lys Ile Glu Ser Gln Thr Gln Glu Glu Val Arg Asp Ser Lys Glu 
225                 230                 235                 240 


Asn Ile Glu Lys Asn Glu Gln Ile Asn Asp Glu Met Lys Arg Ser Gly 
                245                 250                 255     


Gln Leu Gly Ile Gln Glu Glu Gly Leu Arg Lys Glu Ser Lys Asp Gln 
            260                 265                 270         


Leu Ser Asp Asp Val Ser Lys Val Ile Ala Tyr Leu Lys Arg Leu Val 
        275                 280                 285             


Asn Ala Ala Gly Ser Gly Arg Leu Gln Asn Gly Gln Asn Gly Glu Arg 
    290                 295                 300                 


Ala Thr Arg Leu Phe Glu Lys Pro Leu Asp Ser Gln Ser Ile Tyr Gln 
305                 310                 315                 320 


Leu Ile Glu Ile Ser Arg Asn Leu Gln Ile Pro Pro Glu Asp Leu Ile 
                325                 330                 335     


Glu Met Leu Lys Thr Gly Glu Lys Pro Asn Gly Ser Val Glu Pro Glu 
            340                 345                 350         


Arg Glu Leu Asp Leu Pro Val Asp Leu Asp Asp Ile Ser Glu Ala Asp 
        355                 360                 365             


Leu Asp His Pro Asp Leu Phe Gln Asn Arg Met Leu Ser Lys Ser Gly 
    370                 375                 380                 


Tyr Pro Lys Thr Pro Gly Gly Ala Gly Thr Glu Ala Leu Pro Asp Gly 
385                 390                 395                 400 


Leu Ser Val Glu Asp Ile Leu Asn Leu Leu Gly Met Glu Ser Ala Ala 
                405                 410                 415     


Asn Gln Lys Thr Ser Tyr Phe Pro Asn Pro Tyr Asn Gln Glu Lys Val 
            420                 425                 430         


Leu Pro Arg Leu Pro Tyr Gly Ala Gly Arg Ser Arg Ser Asn Gln Leu 
        435                 440                 445             


Pro Lys Ala Ala Trp Ile Pro His Val Glu Asn Arg Gln Met Ala Tyr 
    450                 455                 460                 


Glu Asn Leu Asn Asp Lys Asp Gln Glu Leu Gly Glu Tyr Leu Ala Arg 
465                 470                 475                 480 


Met Leu Val Lys Tyr Pro Glu Ile Ile Asn Ser Asn Gln Val Lys Arg 
                485                 490                 495     


Val Pro Gly Gln Gly Ser Ser Glu Gly Asp Leu Gln Glu Glu Glu Gln 
            500                 505                 510         


Ile Glu Gln Ala Ile Lys Glu His Leu Asn Gln Gly Ser Ser Gln Glu 
        515                 520                 525             


Thr Asp Lys Leu Ala Pro Val Ser Lys Arg Phe Pro Val Gly Pro Pro 
    530                 535                 540                 


Lys Asn Asp Asp Thr Pro Asn Arg Gln Tyr Trp Asp Glu Asp Leu Leu 
545                 550                 555                 560 


Met Lys Val Leu Glu Tyr Leu Asn Gln Glu Lys Ala Glu Lys Gly Arg 
                565                 570                 575     


Glu His Ile Ala Lys Arg Ala Met Glu Asn Met 
            580                 585         


<210>  2082
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  2082

Phe Ser Tyr Phe Val Ile Leu Ala Glu Asn Gly Phe Leu Pro Gly Asn 
1               5                   10                  15      


Leu Val Gly Ile Arg Leu Asn Trp Asp Asp Arg Thr Val Asn Asp Leu 
            20                  25                  30          


Glu Asp Ser Tyr Gly Gln Gln Trp Thr Tyr Glu Gln Arg Lys Val Val 
        35                  40                  45              


Glu Phe Thr Cys 
    50          


<210>  2083
<211>  625
<212>  PRT
<213>  Homo Sapiens

<400>  2083

Val Ala Gly Ala Glu Gly Pro Asp Glu Asp Ser Ser Asn Arg Glu Asn 
1               5                   10                  15      


Ala Ile Glu Asp Glu Glu Glu Glu Glu Glu Glu Asp Asp Asp Glu Glu 
            20                  25                  30          


Glu Asp Asp Leu Glu Val Lys Glu Glu Asn Gly Val Leu Val Leu Asn 
        35                  40                  45              


Asp Ala Asn Phe Asp Asn Phe Val Ala Asp Lys Asp Thr Val Leu Leu 
    50                  55                  60                  


Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Gln Phe Ala Pro Glu 
65                  70                  75                  80  


Tyr Glu Lys Ile Ala Asn Ile Leu Lys Asp Lys Asp Pro Pro Ile Pro 
                85                  90                  95      


Val Ala Lys Ile Asp Ala Thr Ser Ala Ser Val Leu Ala Ser Arg Phe 
            100                 105                 110         


Asp Val Ser Gly Tyr Pro Thr Ile Lys Ile Leu Lys Lys Gly Gln Ala 
        115                 120                 125             


Val Asp Tyr Glu Gly Ser Arg Thr Gln Glu Glu Ile Val Ala Lys Val 
    130                 135                 140                 


Arg Glu Val Ser Gln Pro Asp Trp Thr Pro Pro Pro Glu Val Thr Leu 
145                 150                 155                 160 


Val Leu Thr Lys Glu Asn Phe Asp Glu Val Val Asn Asp Ala Asp Ile 
                165                 170                 175     


Ile Leu Val Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Lys Leu 
            180                 185                 190         


Ala Pro Glu Tyr Glu Lys Ala Ala Lys Glu Leu Ser Lys Arg Ser Pro 
        195                 200                 205             


Pro Ile Pro Leu Ala Lys Val Asp Ala Thr Ala Glu Thr Asp Leu Ala 
    210                 215                 220                 


Lys Arg Phe Asp Val Ser Gly Tyr Pro Thr Leu Lys Ile Phe Arg Lys 
225                 230                 235                 240 


Gly Arg Pro Tyr Asp Tyr Asn Gly Pro Arg Glu Lys Tyr Gly Ile Val 
                245                 250                 255     


Asp Tyr Met Ile Glu Gln Ser Gly Pro Pro Ser Lys Glu Ile Leu Thr 
            260                 265                 270         


Leu Lys Gln Val Gln Glu Phe Leu Lys Asp Gly Asp Asp Val Ile Ile 
        275                 280                 285             


Ile Gly Val Phe Lys Gly Glu Ser Asp Pro Ala Tyr Gln Gln Tyr Gln 
    290                 295                 300                 


Asp Ala Ala Asn Asn Leu Arg Glu Asp Tyr Lys Phe His His Thr Phe 
305                 310                 315                 320 


Ser Thr Glu Ile Ala Lys Phe Leu Lys Val Ser Gln Gly Gln Leu Val 
                325                 330                 335     


Val Met Gln Pro Glu Lys Phe Gln Ser Lys Tyr Glu Pro Arg Ser His 
            340                 345                 350         


Met Met Asp Val Gln Gly Ser Thr Gln Asp Ser Ala Ile Lys Asp Phe 
        355                 360                 365             


Val Leu Lys Tyr Ala Leu Pro Leu Val Gly His Arg Lys Val Ser Asn 
    370                 375                 380                 


Asp Ala Lys Arg Tyr Thr Arg Arg Pro Leu Val Val Val Tyr Tyr Ser 
385                 390                 395                 400 


Val Asp Phe Ser Phe Asp Tyr Arg Ala Ala Thr Gln Phe Trp Arg Ser 
                405                 410                 415     


Lys Val Leu Glu Val Ala Lys Asp Phe Pro Glu Tyr Thr Phe Ala Ile 
            420                 425                 430         


Ala Asp Glu Glu Asp Tyr Ala Gly Glu Val Lys Asp Leu Gly Leu Ser 
        435                 440                 445             


Glu Ser Gly Glu Asp Val Asn Ala Ala Ile Leu Asp Glu Ser Gly Lys 
    450                 455                 460                 


Lys Phe Ala Met Glu Pro Glu Glu Phe Asp Ser Asp Thr Leu Arg Glu 
465                 470                 475                 480 


Phe Val Thr Ala Phe Lys Lys Gly Lys Leu Lys Pro Val Ile Lys Ser 
                485                 490                 495     


Gln Pro Val Pro Lys Asn Asn Lys Gly Pro Val Lys Val Val Val Gly 
            500                 505                 510         


Lys Thr Phe Asp Ser Ile Val Met Asp Pro Lys Lys Asp Val Leu Ile 
        515                 520                 525             


Glu Phe Tyr Ala Pro Trp Cys Gly His Cys Lys Gln Leu Glu Pro Val 
    530                 535                 540                 


Tyr Asn Ser Leu Ala Lys Lys Tyr Lys Gly Gln Lys Gly Leu Val Ile 
545                 550                 555                 560 


Ala Lys Met Asp Ala Thr Ala Asn Asp Val Pro Ser Asp Arg Tyr Lys 
                565                 570                 575     


Val Glu Gly Phe Pro Thr Ile Tyr Phe Ala Pro Ser Gly Asp Lys Lys 
            580                 585                 590         


Asn Pro Val Lys Phe Glu Gly Gly Asp Arg Asp Leu Glu His Leu Ser 
        595                 600                 605             


Lys Phe Ile Glu Glu His Ala Thr Lys Leu Ser Arg Thr Lys Glu Glu 
    610                 615                 620                 


Leu 
625 


<210>  2084
<211>  517
<212>  PRT
<213>  Homo Sapiens

<400>  2084

His Pro Gly Phe Phe Thr Ser Ile Gly Gln Met Thr Asp Leu Ile His 
1               5                   10                  15      


Thr Glu Lys Asp Leu Val Thr Ser Leu Lys Asp Tyr Ile Lys Ala Glu 
            20                  25                  30          


Glu Asp Lys Leu Glu Gln Ile Lys Lys Trp Ala Glu Lys Leu Asp Arg 
        35                  40                  45              


Leu Thr Ser Thr Ala Thr Lys Asp Pro Glu Gly Phe Val Gly His Pro 
    50                  55                  60                  


Val Asn Ala Phe Lys Leu Met Lys Arg Leu Asn Thr Glu Trp Ser Glu 
65                  70                  75                  80  


Leu Glu Asn Leu Val Leu Lys Asp Met Ser Asp Gly Phe Ile Ser Asn 
                85                  90                  95      


Leu Thr Ile Gln Arg Gln Tyr Phe Pro Asn Asp Glu Asp Gln Val Gly 
            100                 105                 110         


Ala Ala Lys Ala Leu Leu Arg Leu Gln Asp Thr Tyr Asn Leu Asp Thr 
        115                 120                 125             


Asp Thr Ile Ser Lys Gly Asn Leu Pro Gly Val Lys His Lys Ser Phe 
    130                 135                 140                 


Leu Thr Ala Glu Asp Cys Phe Glu Leu Gly Lys Val Ala Tyr Thr Glu 
145                 150                 155                 160 


Ala Asp Tyr Tyr His Thr Glu Leu Trp Met Glu Gln Ala Leu Arg Gln 
                165                 170                 175     


Leu Asp Glu Gly Glu Ile Ser Thr Ile Asp Lys Val Ser Val Leu Asp 
            180                 185                 190         


Tyr Leu Ser Tyr Ala Val Tyr Gln Gln Gly Asp Leu Asp Lys Ala Leu 
        195                 200                 205             


Leu Leu Thr Lys Lys Leu Leu Glu Leu Asp Pro Glu His Gln Arg Ala 
    210                 215                 220                 


Asn Gly Asn Leu Lys Tyr Phe Glu Tyr Ile Met Ala Lys Glu Lys Asp 
225                 230                 235                 240 


Val Asn Lys Ser Ala Ser Asp Asp Gln Ser Asp Gln Lys Thr Thr Pro 
                245                 250                 255     


Lys Lys Lys Gly Val Ala Val Asp Tyr Leu Pro Glu Arg Gln Lys Tyr 
            260                 265                 270         


Glu Met Leu Cys Arg Gly Glu Gly Ile Lys Met Thr Pro Arg Arg Gln 
        275                 280                 285             


Lys Lys Leu Phe Cys Arg Tyr His Asp Gly Asn Arg Asn Pro Lys Phe 
    290                 295                 300                 


Ile Leu Ala Pro Ala Lys Gln Glu Asp Glu Trp Asp Lys Pro Arg Ile 
305                 310                 315                 320 


Ile Arg Phe His Asp Ile Ile Ser Asp Ala Glu Ile Glu Ile Val Lys 
                325                 330                 335     


Asp Leu Ala Lys Pro Arg Leu Arg Arg Ala Thr Ile Ser Asn Pro Ile 
            340                 345                 350         


Thr Gly Asp Leu Glu Thr Val His Tyr Arg Ile Ser Lys Ser Ala Trp 
        355                 360                 365             


Leu Ser Gly Tyr Glu Asn Pro Val Val Ser Arg Ile Asn Met Arg Ile 
    370                 375                 380                 


Gln Asp Leu Thr Gly Leu Asp Val Ser Thr Ala Glu Glu Leu Gln Val 
385                 390                 395                 400 


Ala Asn Tyr Gly Val Gly Gly Gln Tyr Glu Pro His Phe Asp Phe Ala 
                405                 410                 415     


Arg Lys Asp Glu Pro Asp Ala Phe Lys Glu Leu Gly Thr Gly Asn Arg 
            420                 425                 430         


Ile Ala Thr Trp Leu Phe Tyr Met Ser Asp Val Ser Ala Gly Gly Ala 
        435                 440                 445             


Thr Val Phe Pro Glu Val Gly Ala Ser Val Trp Pro Lys Lys Gly Thr 
    450                 455                 460                 


Ala Val Phe Trp Tyr Asn Leu Phe Ala Ser Gly Glu Gly Asp Tyr Ser 
465                 470                 475                 480 


Thr Arg His Ala Ala Cys Pro Val Leu Val Gly Asn Lys Trp Val Ser 
                485                 490                 495     


Asn Lys Trp Leu His Glu Arg Gly Gln Glu Phe Arg Arg Pro Cys Thr 
            500                 505                 510         


Leu Ser Glu Leu Glu 
        515         


<210>  2085
<211>  304
<212>  PRT
<213>  Homo Sapiens

<400>  2085

Ala Thr Pro Ala Leu Arg Phe Val Ala Val Gly Asp Trp Gly Gly Val 
1               5                   10                  15      


Pro Asn Ala Pro Phe His Thr Ala Arg Glu Met Ala Asn Ala Lys Glu 
            20                  25                  30          


Ile Ala Arg Thr Val Gln Ile Leu Gly Ala Asp Phe Ile Leu Ser Leu 
        35                  40                  45              


Gly Asp Asn Phe Tyr Phe Thr Gly Val Gln Asp Ile Asn Asp Lys Arg 
    50                  55                  60                  


Phe Gln Glu Thr Phe Glu Asp Val Phe Ser Asp Arg Ser Leu Arg Lys 
65                  70                  75                  80  


Val Pro Trp Tyr Val Leu Ala Gly Asn His Asp His Leu Gly Asn Val 
                85                  90                  95      


Ser Ala Gln Ile Ala Tyr Ser Lys Ile Ser Lys Arg Trp Asn Phe Pro 
            100                 105                 110         


Ser Pro Phe Tyr Arg Leu His Phe Lys Ile Pro Gln Thr Asn Val Ser 
        115                 120                 125             


Val Ala Ile Phe Met Leu Asp Thr Val Thr Leu Cys Gly Asn Ser Asp 
    130                 135                 140                 


Asp Phe Leu Ser Gln Gln Pro Glu Arg Pro Arg Asp Val Lys Leu Ala 
145                 150                 155                 160 


Arg Thr Gln Leu Ser Trp Leu Lys Lys Gln Leu Ala Ala Ala Arg Glu 
                165                 170                 175     


Asp Tyr Val Leu Val Ala Gly His Tyr Pro Val Trp Ser Ile Ala Glu 
            180                 185                 190         


His Gly Pro Thr His Cys Leu Val Lys Gln Leu Arg Pro Leu Leu Ala 
        195                 200                 205             


Thr Tyr Gly Val Thr Ala Tyr Leu Cys Gly His Asp His Asn Leu Gln 
    210                 215                 220                 


Tyr Leu Gln Asp Glu Asn Gly Val Gly Tyr Val Leu Ser Gly Ala Gly 
225                 230                 235                 240 


Asn Phe Met Asp Pro Ser Lys Arg His Gln Arg Lys Val Pro Asn Gly 
                245                 250                 255     


Tyr Leu Arg Phe His Tyr Gly Thr Glu Asp Ser Leu Gly Gly Phe Ala 
            260                 265                 270         


Tyr Val Glu Ile Ser Ser Lys Glu Met Thr Val Thr Tyr Ile Glu Ala 
        275                 280                 285             


Ser Gly Lys Ser Leu Phe Lys Thr Arg Leu Pro Arg Arg Ala Arg Pro 
    290                 295                 300                 


<210>  2086
<211>  196
<212>  PRT
<213>  Homo Sapiens

<400>  2086

Ala Ala Ile Gly Ser Cys Ser Lys Glu Tyr Arg Val Leu Leu Gly Gln 
1               5                   10                  15      


Leu Gln Lys Gln Thr Asp Leu Met Gln Asp Thr Ser Arg Leu Leu Asp 
            20                  25                  30          


Pro Tyr Ile Arg Ile Gln Gly Leu Asp Val Pro Lys Leu Arg Glu His 
        35                  40                  45              


Cys Arg Glu Arg Pro Gly Ala Phe Pro Ser Glu Glu Thr Leu Arg Gly 
    50                  55                  60                  


Leu Gly Arg Arg Gly Phe Leu Gln Thr Leu Asn Ala Thr Leu Gly Cys 
65                  70                  75                  80  


Val Leu His Arg Leu Ala Asp Leu Glu Gln Arg Leu Pro Lys Ala Gln 
                85                  90                  95      


Asp Leu Glu Arg Ser Gly Leu Asn Ile Glu Asp Leu Glu Lys Leu Gln 
            100                 105                 110         


Met Ala Arg Pro Asn Ile Leu Gly Leu Arg Asn Asn Ile Tyr Cys Met 
        115                 120                 125             


Ala Gln Leu Leu Asp Asn Ser Asp Thr Ala Glu Pro Thr Lys Ala Gly 
    130                 135                 140                 


Arg Gly Ala Ser Gln Pro Pro Thr Pro Thr Pro Ala Ser Asp Ala Phe 
145                 150                 155                 160 


Gln Arg Lys Leu Glu Gly Cys Arg Phe Leu His Gly Tyr His Arg Phe 
                165                 170                 175     


Met His Ser Val Gly Arg Val Phe Ser Lys Trp Gly Glu Ser Pro Asn 
            180                 185                 190         


Arg Ser Arg Arg 
        195     


<210>  2087
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  2087

Gly Asp Thr Gln Pro Arg Phe Leu Glu Gln Ala Lys Cys Glu Cys His 
1               5                   10                  15      


Phe Leu Asn Gly Thr Glu Arg Val Trp Asn Leu Ile Arg Tyr Ile Tyr 
            20                  25                  30          


Asn Gln Glu Glu Tyr Ala Arg Tyr Asn Ser Asp Leu Gly Glu Tyr Gln 
        35                  40                  45              


Ala Val Thr Glu Leu Gly Arg Pro Asp Ala Glu Tyr Trp Asn Ser Gln 
    50                  55                  60                  


Lys Asp Leu Leu Glu Arg Arg Arg Ala Glu Val Asp Thr Tyr Cys Arg 
65                  70                  75                  80  


Tyr Asn Tyr Gly Val Val Glu Ser Phe Thr Val Gln Arg Arg Val Gln 
                85                  90                  95      


Pro Lys Val Thr Val Tyr Pro Ser Lys Thr Gln Pro Leu Gln His His 
            100                 105                 110         


Asn Leu Leu Val Cys Ser Val Asn Gly Phe Tyr Pro Gly Ser Ile Glu 
        115                 120                 125             


Val Arg Trp Phe Arg Asn Gly Gln Glu Glu Lys Ala Gly Val Val Ser 
    130                 135                 140                 


Thr Gly Leu Ile Gln Asn Gly Asp Trp Thr Phe Gln Thr Leu Val Met 
145                 150                 155                 160 


Leu Glu Thr Val Pro Arg Ser Gly Glu Val Tyr Thr Cys Gln Val Glu 
                165                 170                 175     


His Pro Ser Met Met Ser Pro Leu Thr Val Gln Trp Ser Ala Arg Ser 
            180                 185                 190         


Glu Ser Ala Gln Ser Lys 
        195             


<210>  2088
<211>  80
<212>  PRT
<213>  Homo Sapiens

<400>  2088

Arg Asn Ser Lys Glu Glu Arg Ile Asp Leu Asp Ala Glu Glu Glu Asn 
1               5                   10                  15      


Ile Gln Glu Gly Pro Lys Glu Thr Ile Glu Ile Glu Thr Gln Val Pro 
            20                  25                  30          


Glu Lys Lys Lys Gly Ile Phe Arg Arg Ala Tyr Asp Leu Phe Cys Gly 
        35                  40                  45              


Leu Glu Gln His Gly Ala Pro Lys Met Thr Glu Glu Glu Glu Lys Ala 
    50                  55                  60                  


Met Lys Met Lys Met Thr Asp Thr Ser Glu Lys Pro Leu Trp Arg Thr 
65                  70                  75                  80  


<210>  2089
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  2089

Ile Gln Phe Thr Glu Ser Cys Ser Met Asp Gln Ser Ala Lys Glu Pro 
1               5                   10                  15      


Leu Ile Asn Tyr Leu Asp Met Glu Tyr Phe Gly Thr Ile Ser Ile Gly 
            20                  25                  30          


Ser Pro Pro Gln Asn Phe Thr Val Ile Phe Asp Thr Gly Ser Ser Asn 
        35                  40                  45              


Leu Trp Val Pro Ser Val Tyr Cys Thr Ser Pro Ala Cys Lys Thr His 
    50                  55                  60                  


Ser Arg Phe Gln Pro Ser Gln Ser Ser Thr Tyr Ser Gln Pro Gly Gln 
65                  70                  75                  80  


Ser Phe Ser Ile Gln Tyr Gly Thr Gly Ser Leu Ser Gly Ile Ile Gly 
                85                  90                  95      


Ala Asp Gln Val Ser Val Glu Gly Leu Thr Val Val Gly Gln Gln Phe 
            100                 105                 110         


Gly Glu Ser Val Thr Glu Pro Gly Gln Thr Phe Val Asp Ala Glu Phe 
        115                 120                 125             


Asp Gly Ile Leu Gly Leu Gly Tyr Pro Ser Leu Ala Val Gly Gly Val 
    130                 135                 140                 


Thr Pro Val Phe Asp Asn Met Met Ala Gln Asn Leu Val Asp Leu Pro 
145                 150                 155                 160 


Met Phe Ser Val Tyr Met Ser Ser Asn Pro Glu Gly Gly Ala Gly Ser 
                165                 170                 175     


Glu Leu Ile Phe Gly Gly Tyr Asp His Ser His Phe Ser Gly Ser Leu 
            180                 185                 190         


Asn Trp Val Pro Val Thr Lys Gln Ala Tyr Trp Gln Ile Ala Leu Asp 
        195                 200                 205             


Asn Ile Gln Val Gly Gly Thr Val Met Phe Cys Ser Glu Gly Cys Gln 
    210                 215                 220                 


Ala Ile Val Asp Thr Gly Thr Ser Leu Ile Thr Gly Pro Ser Asp Lys 
225                 230                 235                 240 


Ile Lys Gln Leu Gln Asn Ala Ile Gly Ala Ala Pro Val Asp Gly Glu 
                245                 250                 255     


Tyr Ala Val Glu Cys Ala Asn Leu Asn Val Met Pro Asp Val Thr Phe 
            260                 265                 270         


Thr Ile Asn Gly Val Pro Tyr Thr Leu Ser Pro Thr Ala Tyr Thr Leu 
        275                 280                 285             


Leu Asp Phe Val Asp Gly Met Gln Phe Cys Ser Ser Gly Phe Gln Gly 
    290                 295                 300                 


Leu Asp Ile His Pro Pro Ala Gly Pro Leu Trp Ile Leu Gly Asp Val 
305                 310                 315                 320 


Phe Ile Arg Gln Phe Tyr Ser Val Phe Asp Arg Gly Asn Asn Arg Val 
                325                 330                 335     


Gly Leu Ala Pro Ala Val Pro 
            340             


<210>  2090
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  2090

Thr Met Cys Ser Ala Gln Asp Arg Thr Asp Leu Leu Asn Val Cys Met 
1               5                   10                  15      


Asp Ala Lys His His Lys Thr Lys Pro Gly Pro Glu Asp Lys Leu His 
            20                  25                  30          


Asp Gln Cys Ser Pro Trp Lys Lys Asn Ala Cys Cys Thr Ala Ser Thr 
        35                  40                  45              


Ser Gln Glu Leu His Lys Asp Thr Ser Arg Leu Tyr Asn Phe Asn Trp 
    50                  55                  60                  


Asp His Cys Gly Lys Met Glu Pro Ala Cys Lys Arg His Phe Ile Gln 
65                  70                  75                  80  


Asp Thr Cys Leu Tyr Glu Cys Ser Pro Asn Leu Gly Pro Trp Ile Gln 
                85                  90                  95      


Gln Val Asn Gln Ser Trp Arg Lys Glu Arg Phe Leu Asp Val Pro Leu 
            100                 105                 110         


Cys Lys Glu Asp Cys Gln Arg Trp Trp Glu Asp Cys His Thr Ser His 
        115                 120                 125             


Thr Cys Lys Ser Asn Trp His Arg Gly Trp Asp Trp Thr Ser Gly Val 
    130                 135                 140                 


Asn Lys Cys Pro Ala Gly Ala Leu Cys Arg Thr Phe Glu Ser Tyr Phe 
145                 150                 155                 160 


Pro Thr Pro Ala Ala Leu Cys Glu Gly Leu Trp Ser His Ser Tyr Lys 
                165                 170                 175     


Val Ser Asn Tyr Ser Arg Gly Ser Gly Arg Cys Ile Gln Met Trp Phe 
            180                 185                 190         


Asp Ser Ala Gln Gly Asn Pro Asn Glu Glu Val Ala Arg Phe Tyr Ala 
        195                 200                 205             


Ala Ala Met His Val Asn 
    210                 


<210>  2091
<211>  406
<212>  PRT
<213>  Homo Sapiens

<400>  2091

Leu Asp Phe Asn Tyr His Arg Gln Glu Gly Met Glu Ala Phe Leu Lys 
1               5                   10                  15      


Thr Val Ala Gln Asn Tyr Ser Ser Val Thr His Leu His Ser Ile Gly 
            20                  25                  30          


Lys Ser Val Lys Gly Arg Asn Leu Trp Val Leu Val Val Gly Arg Phe 
        35                  40                  45              


Pro Lys Glu His Arg Ile Gly Ile Pro Glu Phe Lys Tyr Val Ala Asn 
    50                  55                  60                  


Met His Gly Asp Glu Thr Val Gly Arg Glu Leu Leu Leu His Leu Ile 
65                  70                  75                  80  


Asp Tyr Leu Val Thr Ser Asp Gly Lys Asp Pro Glu Ile Thr Asn Leu 
                85                  90                  95      


Ile Asn Ser Thr Arg Ile His Ile Met Pro Ser Met Asn Pro Asp Gly 
            100                 105                 110         


Phe Glu Ala Val Lys Lys Pro Asp Cys Tyr Tyr Ser Ile Gly Arg Glu 
        115                 120                 125             


Asn Tyr Asn Gln Tyr Asp Leu Asn Arg Asn Phe Pro Asp Ala Phe Glu 
    130                 135                 140                 


Tyr Asn Asn Val Ser Arg Gln Pro Glu Thr Val Ala Val Met Lys Trp 
145                 150                 155                 160 


Leu Lys Thr Glu Thr Phe Val Leu Ser Ala Asn Leu His Gly Gly Ala 
                165                 170                 175     


Leu Val Ala Ser Tyr Pro Phe Asp Asn Gly Val Gln Ala Thr Gly Ala 
            180                 185                 190         


Leu Tyr Ser Arg Ser Leu Thr Pro Asp Asp Asp Val Phe Gln Tyr Leu 
        195                 200                 205             


Ala His Thr Tyr Ala Ser Arg Asn Pro Asn Met Lys Lys Gly Asp Glu 
    210                 215                 220                 


Cys Lys Asn Lys Met Asn Phe Pro Asn Gly Val Thr Asn Gly Tyr Ser 
225                 230                 235                 240 


Trp Tyr Pro Leu Gln Gly Gly Met Gln Asp Tyr Asn Tyr Ile Trp Ala 
                245                 250                 255     


Gln Cys Phe Glu Ile Thr Leu Glu Leu Ser Cys Cys Lys Tyr Pro Arg 
            260                 265                 270         


Glu Glu Lys Leu Pro Ser Phe Trp Asn Asn Asn Lys Ala Ser Leu Ile 
        275                 280                 285             


Glu Tyr Ile Lys Gln Val His Leu Gly Val Lys Gly Gln Val Phe Asp 
    290                 295                 300                 


Gln Asn Gly Asn Pro Leu Pro Asn Val Ile Val Glu Val Gln Asp Arg 
305                 310                 315                 320 


Lys His Ile Cys Pro Tyr Arg Thr Asn Lys Tyr Gly Glu Tyr Tyr Leu 
                325                 330                 335     


Leu Leu Leu Pro Gly Ser Tyr Ile Ile Asn Val Thr Val Pro Gly His 
            340                 345                 350         


Asp Pro His Ile Thr Lys Val Ile Ile Pro Glu Lys Ser Gln Asn Phe 
        355                 360                 365             


Ser Ala Leu Lys Lys Asp Ile Leu Leu Pro Phe Gln Gly Gln Leu Asp 
    370                 375                 380                 


Ser Ile Pro Val Ser Asn Pro Ser Cys Pro Met Ile Pro Leu Tyr Arg 
385                 390                 395                 400 


Asn Leu Pro Asp His Ser 
                405     


<210>  2092
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2092

Asp His Thr Pro Lys Tyr Gln Asp Arg Leu Ala Thr Pro Gly Leu Met 
1               5                   10                  15      


Ile Arg Pro Lys Thr Glu Asn Leu Asp Val Ile Val Asn Val Ser Asp 
            20                  25                  30          


Thr Glu Ser Trp Asp Gln His Val Gln Lys Leu Asn Lys Phe Leu Glu 
        35                  40                  45              


Pro Tyr Asn Asp Ser Ile Gln Ala Gln Lys Asn Asp Val Cys Arg Pro 
    50                  55                  60                  


Gly Arg Tyr Tyr Glu Gln Pro Asp Asn Gly Val Leu Asn Tyr Pro Lys 
65                  70                  75                  80  


Arg Ala Cys Gln Phe Asn Arg Thr Gln Leu Gly Asn Cys Ser Gly Ile 
                85                  90                  95      


Gly Asp Ser Thr His Tyr Gly Tyr Ser Thr Gly Gln Pro Cys Val Phe 
            100                 105                 110         


Ile Lys Met Asn Arg Val Ile Asn Phe Tyr Ala Gly Ala Asn Gln Ser 
        115                 120                 125             


Met Asn Val Thr Cys Ala Gly Lys Arg Asp Glu Asp Ala Glu Asn Leu 
    130                 135                 140                 


Gly Asn Phe Val Met Phe Pro Ala Asn Gly Asn Ile Asp Leu Met Tyr 
145                 150                 155                 160 


Phe Pro Tyr Tyr Gly Lys Lys Phe His Val Asn Tyr Thr Gln Pro Leu 
                165                 170                 175     


Val Ala Val Lys Phe Leu Asn Val Thr Pro Asn Val Glu Val Asn Val 
            180                 185                 190         


Glu Cys Arg Ile Asn Ala Ala Asn Ile Ala Thr Asp Asp Glu Arg Asp 
        195                 200                 205             


Lys Phe Ala Gly Arg Val Ala Phe Lys Leu Arg Ile Asn Lys Thr 
    210                 215                 220             


<210>  2093
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  2093

Asn Leu Val Asn Phe His Arg Met Ile Lys Leu Thr Thr Gly Lys Glu 
1               5                   10                  15      


Ala Ala Leu Ser Tyr Gly Phe Tyr Gly Cys His Cys Gly Val Gly Gly 
            20                  25                  30          


Arg Gly Ser Pro Lys Asp Ala Thr Asp Arg Cys Cys Val Thr His Asp 
        35                  40                  45              


Cys Cys Tyr Lys Arg Leu Glu Lys Arg Gly Cys Gly Thr Lys Phe Leu 
    50                  55                  60                  


Ser Tyr Lys Phe Ser Asn Ser Gly Ser Arg Ile Thr Cys Ala Lys Gln 
65                  70                  75                  80  


Asp Ser Cys Arg Ser Gln Leu Cys Glu Cys Asp Lys Ala Ala Ala Thr 
                85                  90                  95      


Cys Phe Ala Arg Asn Lys Thr Thr Tyr Asn Lys Lys Tyr Gln Tyr Tyr 
            100                 105                 110         


Ser Asn Lys His Cys Arg Gly Ser Thr Pro Arg Cys 
        115                 120                 


<210>  2094
<211>  782
<212>  PRT
<213>  Homo Sapiens

<400>  2094

Asp Asp Glu Val Asp Val Asp Gly Thr Val Glu Glu Asp Leu Gly Lys 
1               5                   10                  15      


Ser Arg Glu Gly Ser Arg Thr Asp Asp Glu Val Val Gln Arg Glu Glu 
            20                  25                  30          


Glu Ala Ile Gln Leu Asp Gly Leu Asn Ala Ser Gln Ile Arg Glu Leu 
        35                  40                  45              


Arg Glu Lys Ser Glu Lys Phe Ala Phe Gln Ala Glu Val Asn Arg Met 
    50                  55                  60                  


Met Lys Leu Ile Ile Asn Ser Leu Tyr Lys Asn Lys Glu Ile Phe Leu 
65                  70                  75                  80  


Arg Glu Leu Ile Ser Asn Ala Ser Asp Ala Leu Asp Lys Ile Arg Leu 
                85                  90                  95      


Ile Ser Leu Thr Asp Glu Asn Ala Leu Ser Gly Asn Glu Glu Leu Thr 
            100                 105                 110         


Val Lys Ile Lys Cys Asp Lys Glu Lys Asn Leu Leu His Val Thr Asp 
        115                 120                 125             


Thr Gly Val Gly Met Thr Arg Glu Glu Leu Val Lys Asn Leu Gly Thr 
    130                 135                 140                 


Ile Ala Lys Ser Gly Thr Ser Glu Phe Leu Asn Lys Met Thr Glu Ala 
145                 150                 155                 160 


Gln Glu Asp Gly Gln Ser Thr Ser Glu Leu Ile Gly Gln Phe Gly Val 
                165                 170                 175     


Gly Phe Tyr Ser Ala Phe Leu Val Ala Asp Lys Val Ile Val Thr Ser 
            180                 185                 190         


Lys His Asn Asn Asp Thr Gln His Ile Trp Glu Ser Asp Ser Asn Glu 
        195                 200                 205             


Phe Ser Val Ile Ala Asp Pro Arg Gly Asn Thr Leu Gly Arg Gly Thr 
    210                 215                 220                 


Thr Ile Thr Leu Val Leu Lys Glu Glu Ala Ser Asp Tyr Leu Glu Leu 
225                 230                 235                 240 


Asp Thr Ile Lys Asn Leu Val Lys Lys Tyr Ser Gln Phe Ile Asn Phe 
                245                 250                 255     


Pro Ile Tyr Val Trp Ser Ser Lys Thr Glu Thr Val Glu Glu Pro Met 
            260                 265                 270         


Glu Glu Glu Glu Ala Ala Lys Glu Glu Lys Glu Glu Ser Asp Asp Glu 
        275                 280                 285             


Ala Ala Val Glu Glu Glu Glu Glu Glu Lys Lys Pro Lys Thr Lys Lys 
    290                 295                 300                 


Val Glu Lys Thr Val Trp Asp Trp Glu Leu Met Asn Asp Ile Lys Pro 
305                 310                 315                 320 


Ile Trp Gln Arg Pro Ser Lys Glu Val Glu Glu Asp Glu Tyr Lys Ala 
                325                 330                 335     


Phe Tyr Lys Ser Phe Ser Lys Glu Ser Asp Asp Pro Met Ala Tyr Ile 
            340                 345                 350         


His Phe Thr Ala Glu Gly Glu Val Thr Phe Lys Ser Ile Leu Phe Val 
        355                 360                 365             


Pro Thr Ser Ala Pro Arg Gly Leu Phe Asp Glu Tyr Gly Ser Lys Lys 
    370                 375                 380                 


Ser Asp Tyr Ile Lys Leu Tyr Val Arg Arg Val Phe Ile Thr Asp Asp 
385                 390                 395                 400 


Phe His Asp Met Met Pro Lys Tyr Leu Asn Phe Val Lys Gly Val Val 
                405                 410                 415     


Asp Ser Asp Asp Leu Pro Leu Asn Val Ser Arg Glu Thr Leu Gln Gln 
            420                 425                 430         


His Lys Leu Leu Lys Val Ile Arg Lys Lys Leu Val Arg Lys Thr Leu 
        435                 440                 445             


Asp Met Ile Lys Lys Ile Ala Asp Asp Lys Tyr Asn Asp Thr Phe Trp 
    450                 455                 460                 


Lys Glu Phe Gly Thr Asn Ile Lys Leu Gly Val Ile Glu Asp His Ser 
465                 470                 475                 480 


Asn Arg Thr Arg Leu Ala Lys Leu Leu Arg Phe Gln Ser Ser His His 
                485                 490                 495     


Pro Thr Asp Ile Thr Ser Leu Asp Gln Tyr Val Glu Arg Met Lys Glu 
            500                 505                 510         


Lys Gln Asp Lys Ile Tyr Phe Met Ala Gly Ser Ser Arg Lys Glu Ala 
        515                 520                 525             


Glu Ser Ser Pro Phe Val Glu Arg Leu Leu Lys Lys Gly Tyr Glu Val 
    530                 535                 540                 


Ile Tyr Leu Thr Glu Pro Val Asp Glu Tyr Cys Ile Gln Ala Leu Pro 
545                 550                 555                 560 


Glu Phe Asp Gly Lys Arg Phe Gln Asn Val Ala Lys Glu Gly Val Lys 
                565                 570                 575     


Phe Asp Glu Ser Glu Lys Thr Lys Glu Ser Arg Glu Ala Val Glu Lys 
            580                 585                 590         


Glu Phe Glu Pro Leu Leu Asn Trp Met Lys Asp Lys Ala Leu Lys Asp 
        595                 600                 605             


Lys Ile Glu Lys Ala Val Val Ser Gln Arg Leu Thr Glu Ser Pro Cys 
    610                 615                 620                 


Ala Leu Val Ala Ser Gln Tyr Gly Trp Ser Gly Asn Met Glu Arg Ile 
625                 630                 635                 640 


Met Lys Ala Gln Ala Tyr Gln Thr Gly Lys Asp Ile Ser Thr Asn Tyr 
                645                 650                 655     


Tyr Ala Ser Gln Lys Lys Thr Phe Glu Ile Asn Pro Arg His Pro Leu 
            660                 665                 670         


Ile Arg Asp Met Leu Arg Arg Ile Lys Glu Asp Glu Asp Asp Lys Thr 
        675                 680                 685             


Val Leu Asp Leu Ala Val Val Leu Phe Glu Thr Ala Thr Leu Arg Ser 
    690                 695                 700                 


Gly Tyr Leu Leu Pro Asp Thr Lys Ala Tyr Gly Asp Arg Ile Glu Arg 
705                 710                 715                 720 


Met Leu Arg Leu Ser Leu Asn Ile Asp Pro Asp Ala Lys Val Glu Glu 
                725                 730                 735     


Glu Pro Glu Glu Glu Pro Glu Glu Thr Ala Glu Asp Thr Thr Glu Asp 
            740                 745                 750         


Thr Glu Gln Asp Glu Asp Glu Glu Met Asp Val Gly Thr Asp Glu Glu 
        755                 760                 765             


Glu Glu Thr Ala Lys Glu Ser Thr Ala Glu Lys Asp Glu Leu 
    770                 775                 780         


<210>  2095
<211>  978
<212>  PRT
<213>  Homo Sapiens

<400>  2095

Met Asn Asn Pro Ala Ile Lys Arg Ile Gly Asn His Ile Thr Lys Ser 
1               5                   10                  15      


Pro Glu Asp Lys Arg Glu Tyr Arg Gly Leu Glu Leu Ala Asn Gly Ile 
            20                  25                  30          


Lys Val Leu Leu Ile Ser Asp Pro Thr Thr Asp Lys Ser Ser Ala Ala 
        35                  40                  45              


Leu Asp Val His Ile Gly Ser Leu Ser Asp Pro Pro Asn Ile Ala Gly 
    50                  55                  60                  


Leu Ser His Phe Cys Glu His Met Leu Phe Leu Gly Thr Lys Lys Tyr 
65                  70                  75                  80  


Pro Lys Glu Asn Glu Tyr Ser Gln Phe Leu Ser Glu His Ala Gly Ser 
                85                  90                  95      


Ser Asn Ala Phe Thr Ser Gly Glu His Thr Asn Tyr Tyr Phe Asp Val 
            100                 105                 110         


Ser His Glu His Leu Glu Gly Ala Leu Asp Arg Phe Ala Gln Phe Phe 
        115                 120                 125             


Leu Cys Pro Leu Phe Asp Glu Ser Cys Lys Asp Arg Glu Val Asn Ala 
    130                 135                 140                 


Val Asp Ser Glu His Glu Lys Asn Val Met Asn Asp Ala Trp Arg Leu 
145                 150                 155                 160 


Phe Gln Leu Glu Lys Ala Thr Gly Asn Pro Lys His Pro Phe Ser Lys 
                165                 170                 175     


Phe Gly Thr Gly Asn Lys Tyr Thr Leu Glu Thr Arg Pro Asn Gln Glu 
            180                 185                 190         


Gly Ile Asp Val Arg Gln Glu Leu Leu Lys Phe His Ser Ala Tyr Tyr 
        195                 200                 205             


Ser Ser Asn Leu Met Ala Val Cys Val Leu Gly Arg Glu Ser Leu Asp 
    210                 215                 220                 


Asp Leu Thr Asn Leu Val Val Lys Leu Phe Ser Glu Val Glu Asn Lys 
225                 230                 235                 240 


Asn Val Pro Leu Pro Glu Phe Pro Glu His Pro Phe Gln Glu Glu His 
                245                 250                 255     


Leu Lys Gln Leu Tyr Lys Ile Val Pro Ile Lys Asp Ile Arg Asn Leu 
            260                 265                 270         


Tyr Val Thr Phe Pro Ile Pro Asp Leu Gln Lys Tyr Tyr Lys Ser Asn 
        275                 280                 285             


Pro Gly His Tyr Leu Gly His Leu Ile Gly His Glu Gly Pro Gly Ser 
    290                 295                 300                 


Leu Leu Ser Glu Leu Lys Ser Lys Gly Trp Val Asn Thr Leu Val Gly 
305                 310                 315                 320 


Gly Gln Lys Glu Gly Ala Arg Gly Phe Met Phe Phe Ile Ile Asn Val 
                325                 330                 335     


Asp Leu Thr Glu Glu Gly Leu Leu His Val Glu Asp Ile Ile Leu His 
            340                 345                 350         


Met Phe Gln Tyr Ile Gln Lys Leu Arg Ala Glu Gly Pro Gln Glu Trp 
        355                 360                 365             


Val Phe Gln Glu Cys Lys Asp Leu Asn Ala Val Ala Phe Arg Phe Lys 
    370                 375                 380                 


Asp Lys Glu Arg Pro Arg Gly Tyr Thr Ser Lys Ile Ala Gly Ile Leu 
385                 390                 395                 400 


His Tyr Tyr Pro Leu Glu Glu Val Leu Thr Ala Glu Tyr Leu Leu Glu 
                405                 410                 415     


Glu Phe Arg Pro Asp Leu Ile Glu Met Val Leu Asp Lys Leu Arg Pro 
            420                 425                 430         


Glu Asn Val Arg Val Ala Ile Val Ser Lys Ser Phe Glu Gly Lys Thr 
        435                 440                 445             


Asp Arg Thr Glu Glu Trp Tyr Gly Thr Gln Tyr Lys Gln Glu Ala Ile 
    450                 455                 460                 


Pro Asp Glu Val Ile Lys Lys Trp Gln Asn Ala Asp Leu Asn Gly Lys 
465                 470                 475                 480 


Phe Lys Leu Pro Thr Lys Asn Glu Phe Ile Pro Thr Asn Phe Glu Ile 
                485                 490                 495     


Leu Pro Leu Glu Lys Glu Ala Thr Pro Tyr Pro Ala Leu Ile Lys Asp 
            500                 505                 510         


Thr Ala Met Ser Lys Leu Trp Phe Lys Gln Asp Asp Lys Phe Phe Leu 
        515                 520                 525             


Pro Lys Ala Cys Leu Asn Phe Glu Phe Phe Ser Pro Phe Ala Tyr Val 
    530                 535                 540                 


Asp Pro Leu His Cys Asn Met Ala Tyr Leu Tyr Leu Glu Leu Leu Lys 
545                 550                 555                 560 


Asp Ser Leu Asn Glu Tyr Ala Tyr Ala Ala Glu Leu Ala Gly Leu Ser 
                565                 570                 575     


Tyr Asp Leu Gln Asn Thr Ile Tyr Gly Met Tyr Leu Ser Val Lys Gly 
            580                 585                 590         


Tyr Asn Asp Lys Gln Pro Ile Leu Leu Lys Lys Ile Ile Glu Lys Met 
        595                 600                 605             


Ala Thr Phe Glu Ile Asp Glu Lys Arg Phe Glu Ile Ile Lys Glu Ala 
    610                 615                 620                 


Tyr Met Arg Ser Leu Asn Asn Phe Arg Ala Glu Gln Pro His Gln His 
625                 630                 635                 640 


Ala Met Tyr Tyr Leu Arg Leu Leu Met Thr Glu Val Ala Trp Thr Lys 
                645                 650                 655     


Asp Glu Leu Lys Glu Ala Leu Asp Asp Val Thr Leu Pro Arg Leu Lys 
            660                 665                 670         


Ala Phe Ile Pro Gln Leu Leu Ser Arg Leu His Ile Glu Ala Leu Leu 
        675                 680                 685             


His Gly Asn Ile Thr Lys Gln Ala Ala Leu Gly Ile Met Gln Met Val 
    690                 695                 700                 


Glu Asp Thr Leu Ile Glu His Ala His Thr Lys Pro Leu Leu Pro Ser 
705                 710                 715                 720 


Gln Leu Val Arg Tyr Arg Glu Val Gln Leu Pro Asp Arg Gly Trp Phe 
                725                 730                 735     


Val Tyr Gln Gln Arg Asn Glu Val His Asn Asn Cys Gly Ile Glu Ile 
            740                 745                 750         


Tyr Tyr Gln Thr Asp Met Gln Ser Thr Ser Glu Asn Met Phe Leu Glu 
        755                 760                 765             


Leu Phe Cys Gln Ile Ile Ser Glu Pro Cys Phe Asn Thr Leu Arg Thr 
    770                 775                 780                 


Lys Glu Gln Leu Gly Tyr Ile Val Phe Ser Gly Pro Arg Arg Ala Asn 
785                 790                 795                 800 


Gly Ile Gln Gly Leu Arg Phe Ile Ile Gln Ser Glu Lys Pro Pro His 
                805                 810                 815     


Tyr Leu Glu Ser Arg Val Glu Ala Phe Leu Ile Thr Met Glu Lys Ser 
            820                 825                 830         


Ile Glu Asp Met Thr Glu Glu Ala Phe Gln Lys His Ile Gln Ala Leu 
        835                 840                 845             


Ala Ile Arg Arg Leu Asp Lys Pro Lys Lys Leu Ser Ala Glu Cys Ala 
    850                 855                 860                 


Lys Tyr Trp Gly Glu Ile Ile Ser Gln Gln Tyr Asn Phe Asp Arg Asp 
865                 870                 875                 880 


Asn Thr Glu Val Ala Tyr Leu Lys Thr Leu Thr Lys Glu Asp Ile Ile 
                885                 890                 895     


Lys Phe Tyr Lys Glu Met Leu Ala Val Asp Ala Pro Arg Arg His Lys 
            900                 905                 910         


Val Ser Val His Val Leu Ala Arg Glu Met Asp Ser Cys Pro Val Val 
        915                 920                 925             


Gly Glu Phe Pro Cys Gln Asn Asp Ile Asn Leu Ser Gln Ala Pro Ala 
    930                 935                 940                 


Leu Pro Gln Pro Glu Val Ile Gln Asn Met Thr Glu Phe Lys Arg Gly 
945                 950                 955                 960 


Leu Pro Leu Phe Pro Leu Val Lys Pro His Ile Asn Phe Met Ala Ala 
                965                 970                 975     


Lys Leu 
        


<210>  2096
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  2096

Ala Arg Ser Thr Asp Thr Phe Asn Tyr Ala Thr Tyr His Thr Leu Glu 
1               5                   10                  15      


Glu Ile Tyr Asp Phe Leu Asp Leu Leu Val Ala Glu Asn Pro His Leu 
            20                  25                  30          


Val Ser Lys Ile Gln Ile Gly Asn Thr Tyr Glu Gly Arg Pro Ile Tyr 
        35                  40                  45              


Val Leu Lys Phe Ser Thr Gly Gly Ser Lys Arg Pro Ala Ile Trp Ile 
    50                  55                  60                  


Asp Thr Gly Ile His Ser Arg Glu Trp Val Thr Gln Ala Ser Gly Val 
65                  70                  75                  80  


Trp Phe Ala Lys Lys Ile Thr Gln Asp Tyr Gly Gln Asp Ala Ala Phe 
                85                  90                  95      


Thr Ala Ile Leu Asp Thr Leu Asp Ile Phe Leu Glu Ile Ile Thr Asn 
            100                 105                 110         


Pro Asp Gly Phe Ala Phe Thr His Ser Thr Asn Arg Met Trp Arg Lys 
        115                 120                 125             


Thr Arg Ser His Thr Ala Gly Ser Leu Cys Ile Gly Val Asp Pro Asn 
    130                 135                 140                 


Arg Asn Trp Asp Ala Gly Phe Gly Leu Ser Gly Ala Ser Ser Asn Pro 
145                 150                 155                 160 


Cys Ser Glu Thr Tyr Arg Gly Lys Phe Ala Asn Ser Glu Val Glu Val 
                165                 170                 175     


Lys Ser Ile Val Asp Phe Val Lys Asp His Gly Asn Ile Lys Ala Phe 
            180                 185                 190         


Ile Ser Ile His Ser Tyr Ser Gln Leu Leu Met Tyr Pro Tyr Gly Tyr 
        195                 200                 205             


Lys Thr Glu Pro Val Pro Asp Gln Asp Glu Leu Asp Gln Leu Ser Lys 
    210                 215                 220                 


Ala Ala Val Thr Ala Leu Ala Ser Leu Tyr Gly Thr Lys Phe Asn Tyr 
225                 230                 235                 240 


Gly Ser Ile Ile Lys Ala Ile Tyr Gln Ala Ser Gly Ser Thr Ile Asp 
                245                 250                 255     


Trp Thr Tyr Ser Gln Gly Ile Lys Tyr Ser Phe Thr Phe Glu Leu Arg 
            260                 265                 270         


Asp Thr Gly Arg Tyr Gly Phe Leu Leu Pro Ala Ser Gln Ile Ile Pro 
        275                 280                 285             


Thr Ala Lys Glu Thr Trp Leu Ala Leu Leu Thr Ile Met Glu His Thr 
    290                 295                 300                 


Leu Asn His Pro Tyr 
305                 


<210>  2097
<211>  307
<212>  PRT
<213>  Homo Sapiens

<400>  2097

Ala Thr Gly His Ser Tyr Glu Lys Tyr Asn Lys Trp Glu Thr Ile Glu 
1               5                   10                  15      


Ala Trp Thr Gln Gln Val Ala Thr Glu Asn Pro Ala Leu Ile Ser Arg 
            20                  25                  30          


Ser Val Ile Gly Thr Thr Phe Glu Gly Arg Ala Ile Tyr Leu Leu Lys 
        35                  40                  45              


Val Gly Lys Ala Gly Gln Asn Lys Pro Ala Ile Phe Met Asp Cys Gly 
    50                  55                  60                  


Phe His Ala Arg Glu Trp Ile Ser Pro Ala Phe Cys Gln Trp Phe Val 
65                  70                  75                  80  


Arg Glu Ala Val Arg Thr Tyr Gly Arg Glu Ile Gln Val Thr Glu Leu 
                85                  90                  95      


Leu Asp Lys Leu Asp Phe Tyr Val Leu Pro Val Leu Asn Ile Asp Gly 
            100                 105                 110         


Tyr Ile Tyr Thr Trp Thr Lys Ser Arg Phe Trp Arg Lys Thr Arg Ser 
        115                 120                 125             


Thr His Thr Gly Ser Ser Cys Ile Gly Thr Asp Pro Asn Arg Asn Phe 
    130                 135                 140                 


Asp Ala Gly Trp Cys Glu Ile Gly Ala Ser Arg Asn Pro Cys Asp Glu 
145                 150                 155                 160 


Thr Tyr Cys Gly Pro Ala Ala Glu Ser Glu Lys Glu Thr Lys Ala Leu 
                165                 170                 175     


Ala Asp Phe Ile Arg Asn Lys Leu Ser Ser Ile Lys Ala Tyr Leu Thr 
            180                 185                 190         


Ile His Ser Tyr Ser Gln Met Met Ile Tyr Pro Tyr Ser Tyr Ala Tyr 
        195                 200                 205             


Lys Leu Gly Glu Asn Asn Ala Glu Leu Asn Ala Leu Ala Lys Ala Thr 
    210                 215                 220                 


Val Lys Glu Leu Ala Ser Leu His Gly Thr Lys Tyr Thr Tyr Gly Pro 
225                 230                 235                 240 


Gly Ala Thr Thr Ile Tyr Pro Ala Ala Gly Gly Ser Asp Asp Trp Ala 
                245                 250                 255     


Tyr Asp Gln Gly Ile Arg Tyr Ser Phe Thr Phe Glu Leu Arg Asp Thr 
            260                 265                 270         


Gly Arg Tyr Gly Phe Leu Leu Pro Glu Ser Gln Ile Arg Ala Thr Cys 
        275                 280                 285             


Glu Glu Thr Phe Leu Ala Ile Lys Tyr Val Ala Ser Tyr Val Leu Glu 
    290                 295                 300                 


His Leu Tyr 
305         


<210>  2098
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  2098

Ile Pro Gly Arg His Ser Tyr Ala Lys Tyr Asn Asn Trp Glu Lys Ile 
1               5                   10                  15      


Val Ala Trp Thr Glu Lys Met Met Asp Lys Tyr Pro Glu Met Val Ser 
            20                  25                  30          


Arg Ile Lys Ile Gly Ser Thr Val Glu Asp Asn Pro Leu Tyr Val Leu 
        35                  40                  45              


Lys Ile Gly Glu Lys Asn Glu Arg Arg Lys Ala Ile Phe Met Asp Cys 
    50                  55                  60                  


Gly Ile His Ala Arg Glu Trp Val Ser Pro Ala Phe Cys Gln Trp Phe 
65                  70                  75                  80  


Val Tyr Gln Ala Thr Lys Thr Tyr Gly Arg Asn Lys Ile Met Thr Lys 
                85                  90                  95      


Leu Leu Asp Arg Met Asn Phe Tyr Ile Leu Pro Val Phe Asn Val Asp 
            100                 105                 110         


Gly Tyr Ile Trp Ser Trp Thr Lys Asn Arg Met Trp Arg Lys Asn Arg 
        115                 120                 125             


Ser Lys Asn Gln Asn Ser Lys Cys Ile Gly Thr Asp Leu Asn Arg Asn 
    130                 135                 140                 


Phe Asn Ala Ser Trp Asn Ser Ile Pro Asn Thr Asn Asp Pro Cys Ala 
145                 150                 155                 160 


Asp Asn Tyr Arg Gly Ser Ala Pro Glu Ser Glu Lys Glu Thr Lys Ala 
                165                 170                 175     


Val Thr Asn Phe Ile Arg Ser His Leu Asn Glu Ile Lys Val Tyr Ile 
            180                 185                 190         


Thr Phe His Ser Tyr Ser Gln Met Leu Leu Phe Pro Tyr Gly Tyr Thr 
        195                 200                 205             


Ser Lys Leu Pro Pro Asn His Glu Asp Leu Ala Lys Val Ala Lys Ile 
    210                 215                 220                 


Gly Thr Asp Val Leu Ser Thr Arg Tyr Glu Thr Arg Tyr Ile Tyr Gly 
225                 230                 235                 240 


Pro Ile Glu Ser Thr Ile Tyr Pro Ile Ser Gly Ser Ser Leu Asp Trp 
                245                 250                 255     


Ala Tyr Asp Leu Gly Ile Lys His Thr Phe Ala Phe Glu Leu Arg Asp 
            260                 265                 270         


Lys Gly Lys Phe Gly Phe Leu Leu Pro Glu Ser Arg Ile Lys Pro Thr 
        275                 280                 285             


Cys Arg Glu Thr Met Leu Ala Val Lys Phe Ile Ala Lys Tyr Ile Leu 
    290                 295                 300                 


Lys His Thr Ser 
305             


<210>  2099
<211>  438
<212>  PRT
<213>  Homo Sapiens

<400>  2099

Val Thr Phe Arg His His Arg Tyr Asp Asp Leu Val Arg Thr Leu Tyr 
1               5                   10                  15      


Lys Val Gln Asn Glu Cys Pro Gly Ile Thr Arg Val Tyr Ser Ile Gly 
            20                  25                  30          


Arg Ser Val Glu Gly Arg His Leu Tyr Val Leu Glu Phe Ser Asp His 
        35                  40                  45              


Pro Gly Ile His Glu Pro Leu Glu Pro Glu Val Lys Tyr Val Gly Asn 
    50                  55                  60                  


Met His Gly Asn Glu Ala Leu Gly Arg Glu Leu Met Leu Gln Leu Ser 
65                  70                  75                  80  


Glu Phe Leu Cys Glu Glu Phe Arg Asn Arg Asn Gln Arg Ile Val Gln 
                85                  90                  95      


Leu Ile Gln Asp Thr Arg Ile His Ile Leu Pro Ser Met Asn Pro Asp 
            100                 105                 110         


Gly Tyr Glu Val Ala Ala Ala Gln Gly Pro Asn Lys Pro Gly Tyr Leu 
        115                 120                 125             


Val Gly Arg Asn Asn Ala Asn Gly Val Asp Leu Asn Arg Asn Phe Pro 
    130                 135                 140                 


Asp Leu Asn Thr Tyr Ile Tyr Tyr Asn Glu Lys Tyr Gly Gly Pro Asn 
145                 150                 155                 160 


His His Leu Pro Leu Pro Asp Asn Trp Lys Ser Gln Val Glu Pro Glu 
                165                 170                 175     


Thr Arg Ala Val Ile Arg Trp Met His Ser Phe Asn Phe Val Leu Ser 
            180                 185                 190         


Ala Asn Leu His Gly Gly Ala Val Val Ala Asn Tyr Pro Tyr Asp Lys 
        195                 200                 205             


Ser Phe Glu His Arg Val Arg Gly Val Arg Arg Thr Ala Ser Thr Pro 
    210                 215                 220                 


Thr Pro Asp Asp Lys Leu Phe Gln Lys Leu Ala Lys Val Tyr Ser Tyr 
225                 230                 235                 240 


Ala His Gly Trp Met Phe Gln Gly Trp Asn Cys Gly Asp Tyr Phe Pro 
                245                 250                 255     


Asp Gly Ile Thr Asn Gly Ala Ser Trp Tyr Ser Leu Ser Lys Gly Met 
            260                 265                 270         


Gln Asp Phe Asn Tyr Leu His Thr Asn Cys Phe Glu Ile Thr Leu Glu 
        275                 280                 285             


Leu Ser Cys Asp Lys Phe Pro Pro Glu Glu Glu Leu Gln Arg Glu Trp 
    290                 295                 300                 


Leu Gly Asn Arg Glu Ala Leu Ile Gln Phe Leu Glu Gln Val His Gln 
305                 310                 315                 320 


Gly Ile Lys Gly Met Val Leu Asp Glu Asn Tyr Asn Asn Leu Ala Asn 
                325                 330                 335     


Ala Val Ile Ser Val Ser Gly Ile Asn His Asp Val Thr Ser Gly Asp 
            340                 345                 350         


His Gly Asp Tyr Phe Arg Leu Leu Leu Pro Gly Ile Tyr Thr Val Ser 
        355                 360                 365             


Ala Thr Ala Pro Gly Tyr Asp Pro Glu Thr Val Thr Val Thr Val Gly 
    370                 375                 380                 


Pro Ala Glu Pro Thr Leu Val Asn Phe His Leu Lys Arg Ser Ile Pro 
385                 390                 395                 400 


Gln Val Ser Pro Val Arg Arg Ala Pro Ser Arg Arg His Gly Val Arg 
                405                 410                 415     


Ala Lys Val Gln Pro Gln Ala Arg Lys Lys Glu Met Glu Met Arg Gln 
            420                 425                 430         


Leu Gln Arg Gly Pro Ala 
        435             


<210>  2100
<211>  489
<212>  PRT
<213>  Homo Sapiens

<400>  2100

Arg Pro Pro Asn Ile Val Leu Ile Phe Ala Asp Asp Leu Gly Tyr Gly 
1               5                   10                  15      


Asp Leu Gly Cys Tyr Gly His Pro Ser Ser Thr Thr Pro Asn Leu Asp 
            20                  25                  30          


Gln Leu Ala Ala Gly Gly Leu Arg Phe Thr Asp Phe Tyr Val Pro Val 
        35                  40                  45              


Ser Leu Cys Thr Pro Ser Arg Ala Ala Leu Leu Thr Gly Arg Leu Pro 
    50                  55                  60                  


Val Arg Met Gly Met Tyr Pro Gly Val Leu Val Pro Ser Ser Arg Gly 
65                  70                  75                  80  


Gly Leu Pro Leu Glu Glu Val Thr Val Ala Glu Val Leu Ala Ala Arg 
                85                  90                  95      


Gly Tyr Leu Thr Gly Met Ala Gly Lys Trp His Leu Gly Val Gly Pro 
            100                 105                 110         


Glu Gly Ala Phe Leu Pro Pro His Gln Gly Phe His Arg Phe Leu Gly 
        115                 120                 125             


Ile Pro Tyr Ser His Asp Gln Gly Pro Cys Gln Asn Leu Thr Cys Phe 
    130                 135                 140                 


Pro Pro Ala Thr Pro Cys Asp Gly Gly Cys Asp Gln Gly Leu Val Pro 
145                 150                 155                 160 


Ile Pro Leu Leu Ala Asn Leu Ser Val Glu Ala Gln Pro Pro Trp Leu 
                165                 170                 175     


Pro Gly Leu Glu Ala Arg Tyr Met Ala Phe Ala His Asp Leu Met Ala 
            180                 185                 190         


Asp Ala Gln Arg Gln Asp Arg Pro Phe Phe Leu Tyr Tyr Ala Ser His 
        195                 200                 205             


His Thr His Tyr Pro Gln Phe Ser Gly Gln Ser Phe Ala Glu Arg Ser 
    210                 215                 220                 


Gly Arg Gly Pro Phe Gly Asp Ser Leu Met Glu Leu Asp Ala Ala Val 
225                 230                 235                 240 


Gly Thr Leu Met Thr Ala Ile Gly Asp Leu Gly Leu Leu Glu Glu Thr 
                245                 250                 255     


Leu Val Ile Phe Thr Ala Asp Asn Gly Pro Glu Thr Met Arg Met Ser 
            260                 265                 270         


Arg Gly Gly Cys Ser Gly Leu Leu Arg Cys Gly Lys Gly Thr Thr Tyr 
        275                 280                 285             


Glu Gly Gly Val Arg Glu Pro Ala Leu Ala Phe Trp Pro Gly His Ile 
    290                 295                 300                 


Ala Pro Gly Val Thr His Glu Leu Ala Ser Ser Leu Asp Leu Leu Pro 
305                 310                 315                 320 


Thr Leu Ala Ala Leu Ala Gly Ala Pro Leu Pro Asn Val Thr Leu Asp 
                325                 330                 335     


Gly Phe Asp Leu Ser Pro Leu Leu Leu Gly Thr Gly Lys Ser Pro Arg 
            340                 345                 350         


Gln Ser Leu Phe Phe Tyr Pro Ser Tyr Pro Asp Glu Val Arg Gly Val 
        355                 360                 365             


Phe Ala Val Arg Thr Gly Lys Tyr Lys Ala His Phe Phe Thr Gln Gly 
    370                 375                 380                 


Ser Ala His Ser Asp Thr Thr Ala Asp Pro Ala Cys His Ala Ser Ser 
385                 390                 395                 400 


Ser Leu Thr Ala His Glu Pro Pro Leu Leu Tyr Asp Leu Ser Lys Asp 
                405                 410                 415     


Pro Gly Glu Asn Tyr Asn Leu Leu Gly Gly Val Ala Gly Ala Thr Pro 
            420                 425                 430         


Glu Val Leu Gln Ala Leu Lys Gln Leu Gln Leu Leu Lys Ala Gln Leu 
        435                 440                 445             


Asp Ala Ala Val Thr Phe Gly Pro Ser Gln Val Ala Arg Gly Glu Asp 
    450                 455                 460                 


Pro Ala Leu Gln Ile Cys Cys His Pro Gly Cys Thr Pro Arg Pro Ala 
465                 470                 475                 480 


Cys Cys His Cys Pro Asp Pro His Ala 
                485                 


<210>  2101
<211>  386
<212>  PRT
<213>  Homo Sapiens

<400>  2101

Lys Glu Leu Lys Phe Val Thr Leu Val Phe Arg His Gly Asp Arg Ser 
1               5                   10                  15      


Pro Ile Asp Thr Phe Pro Thr Asp Pro Ile Lys Glu Ser Ser Trp Pro 
            20                  25                  30          


Gln Gly Phe Gly Gln Leu Thr Gln Leu Gly Met Glu Gln His Tyr Glu 
        35                  40                  45              


Leu Gly Glu Tyr Ile Arg Lys Arg Tyr Arg Lys Phe Leu Asn Glu Ser 
    50                  55                  60                  


Tyr Lys His Glu Gln Val Tyr Ile Arg Ser Thr Asp Val Asp Arg Thr 
65                  70                  75                  80  


Leu Met Ser Ala Met Thr Asn Leu Ala Ala Leu Phe Pro Pro Glu Gly 
                85                  90                  95      


Val Ser Ile Trp Asn Pro Ile Leu Leu Trp Gln Pro Ile Pro Val His 
            100                 105                 110         


Thr Val Pro Leu Ser Glu Asp Gln Leu Leu Tyr Leu Pro Phe Arg Asn 
        115                 120                 125             


Cys Pro Arg Phe Gln Glu Leu Glu Ser Glu Thr Leu Lys Ser Glu Glu 
    130                 135                 140                 


Phe Gln Lys Arg Leu His Pro Tyr Lys Asp Phe Ile Ala Thr Leu Gly 
145                 150                 155                 160 


Lys Leu Ser Gly Leu His Gly Gln Asp Leu Phe Gly Ile Trp Ser Lys 
                165                 170                 175     


Val Tyr Asp Pro Leu Tyr Cys Glu Ser Val His Asn Phe Thr Leu Pro 
            180                 185                 190         


Ser Trp Ala Thr Glu Asp Thr Met Thr Lys Leu Arg Glu Leu Ser Glu 
        195                 200                 205             


Leu Ser Leu Leu Ser Leu Tyr Gly Ile His Lys Gln Lys Glu Lys Ser 
    210                 215                 220                 


Arg Leu Gln Gly Gly Val Leu Val Asn Glu Ile Leu Asn His Met Lys 
225                 230                 235                 240 


Arg Ala Thr Gln Ile Pro Ser Tyr Lys Lys Leu Ile Met Tyr Ser Ala 
                245                 250                 255     


His Asp Thr Thr Val Ser Gly Leu Gln Met Ala Leu Asp Val Tyr Asn 
            260                 265                 270         


Gly Leu Leu Pro Pro Tyr Ala Ser Cys His Leu Thr Glu Leu Tyr Phe 
        275                 280                 285             


Glu Lys Gly Glu Tyr Phe Val Glu Met Tyr Tyr Arg Asn Glu Thr Gln 
    290                 295                 300                 


His Glu Pro Tyr Pro Leu Met Leu Pro Gly Cys Ser Pro Ser Cys Pro 
305                 310                 315                 320 


Leu Glu Arg Phe Ala Glu Leu Ala Gly Pro Val Ile Pro Gln Asp Trp 
                325                 330                 335     


Ser Thr Glu Cys Met Thr Thr Asn Ser His Gln Val Leu Lys Val Ile 
            340                 345                 350         


Phe Ala Val Ala Phe Cys Leu Ile Ser Ala Val Leu Met Val Leu Leu 
        355                 360                 365             


Phe Ile His Ile Arg Arg Gly Leu Cys Trp Gln Arg Glu Ser Tyr Gly 
    370                 375                 380                 


Asn Ile 
385     


<210>  2102
<211>  210
<212>  PRT
<213>  Homo Sapiens

<400>  2102

Arg Ile Ala Trp Ala Arg Thr Glu Leu Leu Asn Val Cys Met Asn Ala 
1               5                   10                  15      


Lys His His Lys Glu Lys Pro Gly Pro Glu Asp Lys Leu His Glu Gln 
            20                  25                  30          


Cys Arg Pro Trp Arg Lys Asn Ala Cys Cys Ser Thr Asn Thr Ser Gln 
        35                  40                  45              


Glu Ala His Lys Asp Val Ser Tyr Leu Tyr Arg Phe Asn Trp Asn His 
    50                  55                  60                  


Cys Gly Glu Met Ala Pro Ala Cys Lys Arg His Phe Ile Gln Asp Thr 
65                  70                  75                  80  


Cys Leu Tyr Glu Cys Ser Pro Asn Leu Gly Pro Trp Ile Gln Gln Val 
                85                  90                  95      


Asp Gln Ser Trp Arg Lys Glu Arg Val Leu Asn Val Pro Leu Cys Lys 
            100                 105                 110         


Glu Asp Cys Glu Gln Trp Trp Glu Asp Cys Arg Thr Ser Tyr Thr Cys 
        115                 120                 125             


Lys Ser Asn Trp His Lys Gly Trp Asn Trp Thr Ser Gly Phe Asn Lys 
    130                 135                 140                 


Cys Ala Val Gly Ala Ala Cys Gln Pro Phe His Phe Tyr Phe Pro Thr 
145                 150                 155                 160 


Pro Thr Val Leu Cys Asn Glu Ile Trp Thr His Ser Tyr Lys Val Ser 
                165                 170                 175     


Asn Tyr Ser Arg Gly Ser Gly Arg Cys Ile Gln Met Trp Phe Asp Pro 
            180                 185                 190         


Ala Gln Gly Asn Pro Asn Glu Glu Val Ala Arg Phe Tyr Ala Ala Ala 
        195                 200                 205             


Met Ser 
    210 


<210>  2103
<211>  516
<212>  PRT
<213>  Homo Sapiens

<400>  2103

Val Phe Gly Val Ala Ala Gly Thr Arg Arg Pro Asn Val Val Leu Leu 
1               5                   10                  15      


Leu Thr Asp Asp Gln Asp Glu Val Leu Gly Gly Met Thr Pro Leu Lys 
            20                  25                  30          


Lys Thr Lys Ala Leu Ile Gly Glu Met Gly Met Thr Phe Ser Ser Ala 
        35                  40                  45              


Tyr Val Pro Ser Ala Leu Cys Cys Pro Ser Arg Ala Ser Ile Leu Thr 
    50                  55                  60                  


Gly Lys Tyr Pro His Asn His His Val Val Asn Asn Thr Leu Glu Gly 
65                  70                  75                  80  


Asn Cys Ser Ser Lys Ser Trp Gln Lys Ile Gln Glu Pro Asn Thr Phe 
                85                  90                  95      


Pro Ala Ile Leu Arg Ser Met Cys Gly Tyr Gln Thr Phe Phe Ala Gly 
            100                 105                 110         


Lys Tyr Leu Asn Glu Tyr Gly Ala Pro Asp Ala Gly Gly Leu Glu His 
        115                 120                 125             


Val Pro Leu Gly Trp Ser Tyr Trp Tyr Ala Leu Glu Lys Asn Ser Lys 
    130                 135                 140                 


Tyr Tyr Asn Tyr Thr Leu Ser Ile Asn Gly Lys Ala Arg Lys His Gly 
145                 150                 155                 160 


Glu Asn Tyr Ser Val Asp Tyr Leu Thr Asp Val Leu Ala Asn Val Ser 
                165                 170                 175     


Leu Asp Phe Leu Asp Tyr Lys Ser Asn Phe Glu Pro Phe Phe Met Met 
            180                 185                 190         


Ile Ala Thr Pro Ala Pro His Ser Pro Trp Thr Ala Ala Pro Gln Tyr 
        195                 200                 205             


Gln Lys Ala Phe Gln Asn Val Phe Ala Pro Arg Asn Lys Asn Phe Asn 
    210                 215                 220                 


Ile His Gly Thr Asn Lys His Trp Leu Ile Arg Gln Ala Lys Thr Pro 
225                 230                 235                 240 


Met Thr Asn Ser Ser Ile Gln Phe Leu Asp Asn Ala Phe Arg Lys Arg 
                245                 250                 255     


Trp Gln Thr Leu Leu Ser Val Asp Asp Leu Val Glu Lys Leu Val Lys 
            260                 265                 270         


Arg Leu Glu Phe Thr Gly Glu Leu Asn Asn Thr Tyr Ile Phe Tyr Thr 
        275                 280                 285             


Ser Asp Asn Gly Tyr His Thr Gly Gln Phe Ser Leu Pro Ile Asp Lys 
    290                 295                 300                 


Arg Gln Leu Tyr Glu Phe Asp Ile Lys Val Pro Leu Leu Val Arg Gly 
305                 310                 315                 320 


Pro Gly Ile Lys Pro Asn Gln Thr Ser Lys Met Leu Val Ala Asn Ile 
                325                 330                 335     


Asp Leu Gly Pro Thr Ile Leu Asp Ile Ala Gly Tyr Asp Leu Asn Lys 
            340                 345                 350         


Thr Gln Met Asp Gly Met Ser Leu Leu Pro Ile Leu Arg Gly Ala Ser 
        355                 360                 365             


Asn Leu Thr Trp Arg Ser Asp Val Leu Val Glu Tyr Gln Gly Glu Gly 
    370                 375                 380                 


Arg Asn Val Thr Asp Pro Thr Cys Pro Ser Leu Ser Pro Gly Val Ser 
385                 390                 395                 400 


Gln Cys Phe Pro Asp Cys Val Cys Glu Asp Ala Tyr Asn Asn Thr Tyr 
                405                 410                 415     


Ala Cys Val Arg Thr Met Ser Ala Leu Trp Asn Leu Gln Tyr Cys Glu 
            420                 425                 430         


Phe Asp Asp Gln Glu Val Phe Val Glu Val Tyr Asn Leu Thr Ala Asp 
        435                 440                 445             


Pro Asp Gln Ile Thr Asn Ile Ala Lys Thr Ile Asp Pro Glu Leu Leu 
    450                 455                 460                 


Gly Lys Met Asn Tyr Arg Leu Met Met Leu Gln Ser Cys Ser Gly Pro 
465                 470                 475                 480 


Thr Cys Arg Thr Pro Gly Val Phe Asp Pro Gly Tyr Arg Phe Asp Pro 
                485                 490                 495     


Arg Leu Met Phe Ser Asn Arg Gly Ser Val Arg Thr Arg Arg Phe Ser 
            500                 505                 510         


Lys His Leu Leu 
        515     


<210>  2104
<211>  194
<212>  PRT
<213>  Homo Sapiens

<400>  2104

Cys Ser Cys Ser Pro Val His Pro Gln Gln Ala Phe Cys Asn Ala Asp 
1               5                   10                  15      


Val Val Ile Arg Ala Lys Ala Val Ser Glu Lys Glu Val Asp Ser Gly 
            20                  25                  30          


Asn Asp Ile Tyr Gly Asn Pro Ile Lys Arg Ile Gln Tyr Glu Ile Lys 
        35                  40                  45              


Gln Ile Lys Met Phe Lys Gly Pro Glu Lys Asp Ile Glu Phe Ile Tyr 
    50                  55                  60                  


Thr Ala Pro Ser Ser Ala Val Cys Gly Val Ser Leu Asp Val Gly Gly 
65                  70                  75                  80  


Lys Lys Glu Tyr Leu Ile Ala Gly Lys Ala Glu Gly Asp Gly Lys Met 
                85                  90                  95      


His Ile Thr Leu Cys Asp Phe Ile Val Pro Trp Asp Thr Leu Ser Thr 
            100                 105                 110         


Thr Gln Lys Lys Ser Leu Asn His Arg Tyr Gln Met Gly Cys Glu Cys 
        115                 120                 125             


Lys Ile Thr Arg Cys Pro Met Ile Pro Cys Tyr Ile Ser Ser Pro Asp 
    130                 135                 140                 


Glu Cys Leu Trp Met Asp Trp Val Thr Glu Lys Asn Ile Asn Gly His 
145                 150                 155                 160 


Gln Ala Lys Phe Phe Ala Cys Ile Lys Arg Ser Asp Gly Ser Cys Ala 
                165                 170                 175     


Trp Tyr Arg Gly Ala Ala Pro Pro Lys Gln Glu Phe Leu Asp Ile Glu 
            180                 185                 190         


Asp Pro 
        


<210>  2105
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2105

Ser Thr Thr Ala Val Gln Thr Pro Thr Ser Gly Glu Pro Leu Val Ser 
1               5                   10                  15      


Thr Ser Glu Pro Leu Ser Ser Lys Met Tyr Thr Thr Ser Ile Thr Ser 
            20                  25                  30          


Asp Pro Lys Ala Asp Ser Thr Gly Asp Gln Thr Ser Ala Leu Pro Pro 
        35                  40                  45              


Ser Thr Ser Ile Asn Glu Gly Ser Pro Leu Trp Thr Ser Ile Gly Ala 
    50                  55                  60                  


Ser Thr Gly Ser Pro Leu Pro Glu Pro Thr Thr Tyr Gln Glu Val Ser 
65                  70                  75                  80  


Ile Lys Met Ser Ser Val Pro Gln Glu Thr Pro His Ala Thr Ser His 
                85                  90                  95      


Pro Ala Val Pro Ile Thr Ala Asn Ser Leu Gly Ser His Thr Val Thr 
            100                 105                 110         


Gly Gly Thr Ile Thr Thr Asn Ser Pro Glu Thr Ser Ser Arg Thr Ser 
        115                 120                 125             


Gly Ala Pro Val Thr Thr Ala Ala Ser Ser Leu Glu Thr Ser Arg Gly 
    130                 135                 140                 


Thr Ser Gly Pro Pro Leu Thr Met Ala Thr Val Ser Leu Glu Thr Ser 
145                 150                 155                 160 


Lys Gly Thr Ser Gly Pro Pro Val Thr Met Ala Thr Asp Ser Leu Glu 
                165                 170                 175     


Thr Ser Thr Gly Thr Thr Gly Pro Pro Val Thr Met Thr Thr Gly Ser 
            180                 185                 190         


Leu Glu Pro Ser Ser Gly Ala Ser Gly Pro Gln Val Ser Ser Val Lys 
        195                 200                 205             


Leu Ser Thr Met Met Ser Pro Thr Thr Ser Thr Asn Ala Ser Thr Val 
    210                 215                 220                 


Pro Phe Arg Asn Pro Asp Glu Asn Ser Arg 
225                 230                 


<210>  2106
<211>  449
<212>  PRT
<213>  Homo Sapiens

<400>  2106

Lys Glu Val Cys Tyr Glu Arg Leu Gly Cys Phe Ser Asp Asp Ser Pro 
1               5                   10                  15      


Trp Ser Gly Ile Thr Glu Arg Pro Leu His Ile Leu Pro Trp Ser Pro 
            20                  25                  30          


Lys Asp Val Asn Thr Arg Phe Leu Leu Tyr Thr Asn Glu Asn Pro Asn 
        35                  40                  45              


Asn Phe Gln Glu Val Ala Ala Asp Ser Ser Ser Ile Ser Gly Ser Asn 
    50                  55                  60                  


Phe Lys Thr Asn Arg Lys Thr Arg Phe Ile Ile His Gly Phe Ile Asp 
65                  70                  75                  80  


Lys Gly Glu Glu Asn Trp Leu Ala Asn Val Cys Lys Asn Leu Phe Lys 
                85                  90                  95      


Val Glu Ser Val Asn Cys Ile Cys Val Asp Trp Lys Gly Gly Ser Arg 
            100                 105                 110         


Thr Gly Tyr Thr Gln Ala Ser Gln Asn Ile Arg Ile Val Gly Ala Glu 
        115                 120                 125             


Val Ala Tyr Phe Val Glu Phe Leu Gln Ser Ala Phe Gly Tyr Ser Pro 
    130                 135                 140                 


Ser Asn Val His Val Ile Gly His Ser Leu Gly Ala His Ala Ala Gly 
145                 150                 155                 160 


Glu Ala Gly Arg Arg Thr Asn Gly Thr Ile Gly Arg Ile Thr Gly Leu 
                165                 170                 175     


Asp Pro Ala Glu Pro Cys Phe Gln Gly Thr Pro Glu Leu Val Arg Leu 
            180                 185                 190         


Asp Pro Ser Asp Ala Lys Phe Val Asp Val Ile His Thr Asp Gly Ala 
        195                 200                 205             


Pro Ile Val Pro Asn Leu Gly Phe Gly Met Ser Gln Val Val Gly His 
    210                 215                 220                 


Leu Asp Phe Phe Pro Asn Gly Gly Val Glu Met Pro Gly Cys Lys Lys 
225                 230                 235                 240 


Asn Ile Leu Ser Gln Ile Val Asp Ile Asp Gly Ile Trp Glu Gly Thr 
                245                 250                 255     


Arg Asp Phe Ala Ala Cys Asn His Leu Arg Ser Tyr Lys Tyr Tyr Thr 
            260                 265                 270         


Asp Ser Ile Val Asn Pro Asp Gly Phe Ala Gly Phe Pro Cys Ala Ser 
        275                 280                 285             


Tyr Asn Val Phe Thr Ala Asn Lys Cys Phe Pro Cys Pro Ser Gly Gly 
    290                 295                 300                 


Cys Pro Gln Met Gly His Tyr Ala Asp Arg Tyr Pro Gly Lys Thr Asn 
305                 310                 315                 320 


Asp Val Gly Gln Lys Phe Tyr Leu Asp Thr Gly Asp Ala Ser Asn Phe 
                325                 330                 335     


Ala Arg Trp Arg Tyr Lys Val Ser Val Thr Leu Ser Gly Lys Lys Val 
            340                 345                 350         


Thr Gly His Ile Leu Val Ser Leu Phe Gly Asn Lys Gly Asn Ser Lys 
        355                 360                 365             


Gln Tyr Glu Ile Phe Lys Gly Thr Leu Lys Pro Asp Ser Thr His Ser 
    370                 375                 380                 


Asn Glu Phe Asp Ser Asp Val Asp Val Gly Asp Leu Gln Met Val Lys 
385                 390                 395                 400 


Phe Ile Trp Tyr Asn Asn Val Ile Asn Pro Thr Leu Pro Arg Val Gly 
                405                 410                 415     


Ala Ser Lys Ile Ile Val Glu Thr Asn Val Gly Lys Gln Phe Asn Phe 
            420                 425                 430         


Cys Ser Pro Glu Thr Val Arg Glu Glu Val Leu Leu Thr Leu Thr Pro 
        435                 440                 445             


Cys 
    


<210>  2107
<211>  649
<212>  PRT
<213>  Homo Sapiens

<400>  2107

Gln Arg Met Phe Glu Ile Asp Tyr Ser Arg Asp Ser Phe Leu Lys Asp 
1               5                   10                  15      


Gly Gln Pro Phe Arg Tyr Ile Ser Gly Ser Ile His Tyr Ser Arg Val 
            20                  25                  30          


Pro Arg Phe Tyr Trp Lys Asp Arg Leu Leu Lys Met Lys Met Ala Gly 
        35                  40                  45              


Leu Asn Ala Ile Gln Thr Tyr Val Pro Trp Asn Phe His Glu Pro Trp 
    50                  55                  60                  


Pro Gly Gln Tyr Gln Phe Ser Glu Asp His Asp Val Glu Tyr Phe Leu 
65                  70                  75                  80  


Arg Leu Ala His Glu Leu Gly Leu Leu Val Ile Leu Arg Pro Gly Pro 
                85                  90                  95      


Tyr Ile Cys Ala Glu Trp Glu Met Gly Gly Leu Pro Ala Trp Leu Leu 
            100                 105                 110         


Glu Lys Glu Ser Ile Leu Leu Arg Ser Ser Asp Pro Asp Tyr Leu Ala 
        115                 120                 125             


Ala Val Asp Lys Trp Leu Gly Val Leu Leu Pro Lys Met Lys Pro Leu 
    130                 135                 140                 


Leu Tyr Gln Asn Gly Gly Pro Val Ile Thr Val Gln Val Glu Asn Glu 
145                 150                 155                 160 


Tyr Gly Ser Tyr Phe Ala Cys Asp Phe Asp Tyr Leu Arg Phe Leu Gln 
                165                 170                 175     


Lys Arg Phe Arg His His Leu Gly Asp Asp Val Val Leu Phe Thr Thr 
            180                 185                 190         


Asp Gly Ala His Lys Thr Phe Leu Lys Cys Gly Ala Leu Gln Gly Leu 
        195                 200                 205             


Tyr Thr Thr Val Asp Phe Gly Thr Gly Ser Asn Ile Thr Asp Ala Phe 
    210                 215                 220                 


Leu Ser Gln Arg Lys Cys Glu Pro Lys Gly Pro Leu Ile Asn Ser Glu 
225                 230                 235                 240 


Phe Tyr Thr Gly Trp Leu Asp His Trp Gly Gln Pro His Ser Thr Ile 
                245                 250                 255     


Lys Thr Glu Ala Val Ala Ser Ser Leu Tyr Asp Ile Leu Ala Arg Gly 
            260                 265                 270         


Ala Ser Val Asn Leu Tyr Met Phe Ile Gly Gly Thr Asn Phe Ala Tyr 
        275                 280                 285             


Trp Asn Gly Ala Asn Ser Pro Tyr Ala Ala Gln Pro Thr Ser Tyr Asp 
    290                 295                 300                 


Tyr Asp Ala Pro Leu Ser Glu Ala Gly Asp Leu Thr Glu Lys Tyr Phe 
305                 310                 315                 320 


Ala Leu Arg Asn Ile Ile Gln Lys Phe Glu Lys Val Pro Glu Gly Pro 
                325                 330                 335     


Ile Pro Pro Ser Thr Pro Lys Phe Ala Tyr Gly Lys Val Thr Leu Glu 
            340                 345                 350         


Lys Leu Lys Thr Val Gly Ala Ala Leu Asp Ile Leu Cys Pro Ser Gly 
        355                 360                 365             


Pro Ile Lys Ser Leu Tyr Pro Leu Thr Phe Ile Gln Val Lys Gln His 
    370                 375                 380                 


Tyr Gly Phe Val Leu Tyr Arg Thr Thr Leu Pro Gln Asp Cys Ser Asn 
385                 390                 395                 400 


Pro Ala Pro Leu Ser Ser Pro Leu Asn Gly Val His Asp Arg Ala Tyr 
                405                 410                 415     


Val Ala Val Asp Gly Ile Pro Gln Gly Val Leu Glu Arg Asn Asn Val 
            420                 425                 430         


Ile Thr Leu Asn Ile Thr Gly Lys Ala Gly Ala Thr Leu Asp Leu Leu 
        435                 440                 445             


Val Glu Asn Met Gly Arg Val Asn Tyr Gly Ala Tyr Ile Asn Asp Phe 
    450                 455                 460                 


Lys Gly Leu Val Ser Asn Leu Thr Leu Ser Ser Asn Ile Leu Thr Asp 
465                 470                 475                 480 


Trp Thr Ile Phe Pro Leu Asp Thr Glu Asp Ala Val Arg Ser His Leu 
                485                 490                 495     


Gly Gly Trp Gly His Arg Asp Ser Gly His His Asp Glu Ala Trp Ala 
            500                 505                 510         


His Asn Ser Ser Asn Tyr Thr Leu Pro Ala Phe Tyr Met Gly Asn Phe 
        515                 520                 525             


Ser Ile Pro Ser Gly Ile Pro Asp Leu Pro Gln Asp Thr Phe Ile Gln 
    530                 535                 540                 


Phe Pro Gly Trp Thr Lys Gly Gln Val Trp Ile Asn Gly Phe Asn Leu 
545                 550                 555                 560 


Gly Arg Tyr Trp Pro Ala Arg Gly Pro Gln Leu Thr Leu Phe Val Pro 
                565                 570                 575     


Gln His Ile Leu Met Thr Ser Ala Pro Asn Thr Ile Thr Val Leu Glu 
            580                 585                 590         


Leu Glu Trp Ala Pro Cys Ser Ser Asp Asp Pro Glu Leu Cys Ala Val 
        595                 600                 605             


Thr Phe Val Asp Arg Pro Val Ile Gly Ser Ser Val Thr Tyr Asp His 
    610                 615                 620                 


Pro Ser Lys Pro Val Glu Lys Arg Leu Met Pro Pro Pro Pro Gln Lys 
625                 630                 635                 640 


Asn Lys Asp Ser Trp Leu Asp His Val 
                645                 


<210>  2108
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  2108

Gln Glu Glu Cys Val Cys Glu Asn Tyr Lys Leu Ala Val Asn Cys Phe 
1               5                   10                  15      


Val Asn Asn Asn Arg Gln Cys Gln Cys Thr Ser Val Gly Ala Gln Asn 
            20                  25                  30          


Thr Val Ile Cys Ser Lys Leu Ala Ala Lys Cys Leu Val Met Lys Ala 
        35                  40                  45              


Glu Met Asn Gly Ser Lys Leu Gly Arg Arg Ala Lys Pro Glu Gly Ala 
    50                  55                  60                  


Leu Gln Asn Asn Asp Gly Leu Tyr Asp Pro Asp Cys Asp Glu Ser Gly 
65                  70                  75                  80  


Leu Phe Lys Ala Lys Gln Cys Asn Gly Thr Ser Met Cys Trp Cys Val 
                85                  90                  95      


Asn Thr Ala Gly Val Arg Arg Thr Asp Lys Asp Thr Glu Ile Thr Cys 
            100                 105                 110         


Ser Glu Arg Val Arg Thr Tyr Trp Ile Ile Ile Glu Leu Lys His Lys 
        115                 120                 125             


Ala Arg Glu Lys Pro Tyr Asp Ser Lys Ser Leu Arg Thr Ala Leu Gln 
    130                 135                 140                 


Lys Glu Ile Thr Thr Arg Tyr Gln Leu Asp Pro Lys Phe Ile Thr Ser 
145                 150                 155                 160 


Ile Leu Tyr Glu Asn Asn Val Ile Thr Ile Asp Leu Val Gln Asn Ser 
                165                 170                 175     


Ser Gln Lys Thr Gln Asn Asp Val Asp Ile Ala Asp Val Ala Tyr Tyr 
            180                 185                 190         


Phe Glu Lys Asp Val Lys Gly Glu Ser Leu Phe His Ser Lys Lys Met 
        195                 200                 205             


Asp Leu Thr Val Asn Gly Glu Gln Leu Asp Leu Asp Pro Gly Gln Thr 
    210                 215                 220                 


Leu Ile Tyr Tyr Val Asp Glu Lys Ala Pro Glu Phe Ser Met Gln Gly 
225                 230                 235                 240 


Leu Lys 
        


<210>  2109
<211>  369
<212>  PRT
<213>  Homo Sapiens

<400>  2109

Asp Phe Phe Arg Asp Glu Ala Glu Arg Ile Met Arg Asp Ser Pro Val 
1               5                   10                  15      


Ile Asp Gly His Asn Asp Leu Pro Trp Gln Leu Leu Asp Met Phe Asn 
            20                  25                  30          


Asn Arg Leu Gln Asp Glu Arg Ala Asn Leu Thr Thr Leu Ala Gly Thr 
        35                  40                  45              


His Thr Asn Ile Pro Lys Leu Arg Ala Gly Phe Val Gly Gly Gln Phe 
    50                  55                  60                  


Trp Ser Val Tyr Thr Pro Cys Asp Thr Gln Asn Lys Asp Ala Val Arg 
65                  70                  75                  80  


Arg Thr Leu Glu Gln Met Asp Val Val His Arg Met Cys Arg Met Tyr 
                85                  90                  95      


Pro Glu Thr Phe Leu Tyr Val Thr Ser Ser Ala Gly Ile Arg Gln Ala 
            100                 105                 110         


Phe Arg Glu Gly Lys Val Ala Ser Leu Ile Gly Val Glu Gly Gly His 
        115                 120                 125             


Ser Ile Asp Ser Ser Leu Gly Val Leu Arg Ala Leu Tyr Gln Leu Gly 
    130                 135                 140                 


Met Arg Tyr Leu Thr Leu Thr His Ser Cys Asn Thr Pro Trp Ala Asp 
145                 150                 155                 160 


Asn Trp Leu Val Asp Thr Gly Asp Ser Glu Pro Gln Ser Gln Gly Leu 
                165                 170                 175     


Ser Pro Phe Gly Gln Arg Val Val Lys Glu Leu Asn Arg Leu Gly Val 
            180                 185                 190         


Leu Ile Asp Leu Ala His Val Ser Val Ala Thr Met Lys Ala Thr Leu 
        195                 200                 205             


Gln Leu Ser Arg Ala Pro Val Ile Phe Ser His Ser Ser Ala Tyr Ser 
    210                 215                 220                 


Val Cys Ala Ser Arg Arg Asn Val Pro Asp Asp Val Leu Arg Leu Val 
225                 230                 235                 240 


Lys Gln Thr Asp Ser Leu Val Met Val Asn Phe Tyr Asn Asn Tyr Ile 
                245                 250                 255     


Ser Cys Thr Asn Lys Ala Asn Leu Ser Gln Val Ala Asp His Leu Asp 
            260                 265                 270         


His Ile Lys Glu Val Ala Gly Ala Arg Ala Val Gly Phe Gly Gly Asp 
        275                 280                 285             


Phe Asp Gly Val Pro Arg Val Pro Glu Gly Leu Glu Asp Val Ser Lys 
    290                 295                 300                 


Tyr Pro Asp Leu Ile Ala Glu Leu Leu Arg Arg Asn Trp Thr Glu Ala 
305                 310                 315                 320 


Glu Val Lys Gly Ala Leu Ala Asp Asn Leu Leu Arg Val Phe Glu Ala 
                325                 330                 335     


Val Glu Gln Ala Ser Asn Leu Thr Gln Ala Pro Glu Glu Glu Pro Ile 
            340                 345                 350         


Pro Leu Asp Gln Leu Gly Gly Ser Cys Arg Thr His Tyr Gly Tyr Ser 
        355                 360                 365             


Ser 
    


<210>  2110
<211>  529
<212>  PRT
<213>  Homo Sapiens

<400>  2110

Gly Tyr Arg Asp Ile Asn Glu Ile Asp Ile Asn Met Asn Asp Pro Leu 
1               5                   10                  15      


Phe Thr Lys Gln Trp Tyr Leu Ile Asn Thr Gly Gln Ala Asp Gly Thr 
            20                  25                  30          


Pro Gly Leu Asp Leu Asn Val Ala Glu Ala Trp Glu Leu Gly Tyr Thr 
        35                  40                  45              


Gly Lys Gly Val Thr Ile Gly Ile Met Asp Asp Gly Ile Asp Tyr Leu 
    50                  55                  60                  


His Pro Asp Leu Ala Ser Asn Tyr Asn Ala Glu Ala Ser Tyr Asp Phe 
65                  70                  75                  80  


Ser Ser Asn Asp Pro Tyr Pro Tyr Pro Arg Tyr Thr Asp Asp Trp Phe 
                85                  90                  95      


Asn Ser His Gly Thr Arg Cys Ala Gly Glu Val Ser Ala Ala Ala Asn 
            100                 105                 110         


Asn Asn Ile Cys Gly Val Gly Val Ala Tyr Asn Ser Lys Val Ala Gly 
        115                 120                 125             


Ile Arg Met Leu Asp Gln Pro Phe Met Thr Asp Ile Ile Glu Ala Ser 
    130                 135                 140                 


Ser Ile Ser His Met Pro Gln Leu Ile Asp Ile Tyr Ser Ala Ser Trp 
145                 150                 155                 160 


Gly Pro Thr Asp Asn Gly Lys Thr Val Asp Gly Pro Arg Glu Leu Thr 
                165                 170                 175     


Leu Gln Ala Met Ala Asp Gly Val Asn Lys Gly Arg Gly Gly Lys Gly 
            180                 185                 190         


Ser Ile Tyr Val Trp Ala Ser Gly Asp Gly Gly Ser Tyr Asp Asp Cys 
        195                 200                 205             


Asn Cys Asp Gly Tyr Ala Ser Ser Met Trp Thr Ile Ser Ile Asn Ser 
    210                 215                 220                 


Ala Ile Asn Asp Gly Arg Thr Ala Leu Tyr Asp Glu Ser Cys Ser Ser 
225                 230                 235                 240 


Thr Leu Ala Ser Thr Phe Ser Asn Gly Arg Lys Arg Asn Pro Glu Ala 
                245                 250                 255     


Gly Val Ala Thr Thr Asp Leu Tyr Gly Asn Cys Thr Leu Arg His Ser 
            260                 265                 270         


Gly Thr Ser Ala Ala Ala Pro Glu Ala Ala Gly Val Phe Ala Leu Ala 
        275                 280                 285             


Leu Glu Ala Asn Leu Gly Leu Thr Trp Arg Asp Met Gln His Leu Thr 
    290                 295                 300                 


Val Leu Thr Ser Lys Arg Asn Gln Leu His Asp Glu Val His Gln Trp 
305                 310                 315                 320 


Arg Arg Asn Gly Val Gly Leu Glu Phe Asn His Leu Phe Gly Tyr Gly 
                325                 330                 335     


Val Leu Asp Ala Gly Ala Met Val Lys Met Ala Lys Asp Trp Lys Thr 
            340                 345                 350         


Val Pro Glu Arg Phe His Cys Val Gly Gly Ser Val Gln Asp Pro Glu 
        355                 360                 365             


Lys Ile Pro Ser Thr Gly Lys Leu Val Leu Thr Leu Thr Thr Asp Ala 
    370                 375                 380                 


Cys Glu Gly Lys Glu Asn Phe Val Arg Tyr Leu Glu His Val Gln Ala 
385                 390                 395                 400 


Val Ile Thr Val Asn Ala Thr Arg Arg Gly Asp Leu Asn Ile Asn Met 
                405                 410                 415     


Thr Ser Pro Met Gly Thr Lys Ser Ile Leu Leu Ser Arg Arg Pro Arg 
            420                 425                 430         


Asp Asp Asp Ser Lys Val Gly Phe Asp Lys Trp Pro Phe Met Thr Thr 
        435                 440                 445             


His Thr Trp Gly Glu Asp Ala Arg Gly Thr Trp Thr Leu Glu Leu Gly 
    450                 455                 460                 


Phe Val Gly Ser Ala Pro Gln Lys Gly Val Leu Lys Glu Trp Thr Leu 
465                 470                 475                 480 


Met Leu His Gly Thr Gln Ser Ala Pro Tyr Ile Asp Gln Val Val Arg 
                485                 490                 495     


Asp Tyr Gln Ser Lys Leu Ala Met Ser Lys Lys Glu Glu Leu Glu Glu 
            500                 505                 510         


Glu Leu Asp Glu Ala Val Glu Arg Ser Leu Lys Ser Ile Leu Asn Lys 
        515                 520                 525             


Asn 
    


<210>  2111
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  2111

Lys Asp Pro Ala Phe Thr Ala Leu Leu Thr Thr Gln Leu Gln Val Gln 
1               5                   10                  15      


Arg Glu Ile Val Asn Lys His Asn Glu Leu Arg Lys Ala Val Ser Pro 
            20                  25                  30          


Pro Ala Ser Asn Met Leu Lys Met Glu Trp Ser Arg Glu Val Thr Thr 
        35                  40                  45              


Asn Ala Gln Arg Trp Ala Asn Lys Cys Thr Leu Gln His Ser Asp Pro 
    50                  55                  60                  


Glu Asp Arg Lys Thr Ser Thr Arg Cys Gly Glu Asn Leu Tyr Met Ser 
65                  70                  75                  80  


Ser Asp Pro Thr Ser Trp Ser Ser Ala Ile Gln Ser Trp Tyr Asp Glu 
                85                  90                  95      


Ile Leu Asp Phe Val Tyr Gly Val Gly Pro Lys Ser Pro Asn Ala Val 
            100                 105                 110         


Val Gly His Tyr Thr Gln Leu Val Trp Tyr Ser Thr Tyr Gln Val Gly 
        115                 120                 125             


Cys Gly Ile Ala Tyr Cys Pro Asn Gln Asp Ser Leu Lys Tyr Tyr Tyr 
    130                 135                 140                 


Val Cys Gln Tyr Cys Pro Ala Gly Asn Asn Met Asn Arg Lys Asn Thr 
145                 150                 155                 160 


Pro Tyr Gln Gln Gly Thr Pro Cys Ala Gly Cys Pro Asp Asp Cys Asp 
                165                 170                 175     


Lys Gly Leu Cys Thr Asn Ser Cys Gln Tyr Gln Asp Leu Leu Ser Asn 
            180                 185                 190         


Cys Asp Ser Leu Lys Asn Thr Ala Gly Cys Glu His Glu Leu Leu Lys 
        195                 200                 205             


Glu Lys Cys Lys Ala Thr Cys Leu Cys Glu Asn Lys Ile Tyr 
    210                 215                 220         


<210>  2112
<211>  469
<212>  PRT
<213>  Homo Sapiens

<400>  2112

Gly Lys Val Leu Val Trp Ala Ala Glu Tyr Ser His Trp Met Asn Ile 
1               5                   10                  15      


Lys Thr Ile Leu Asp Glu Leu Ile Gln Arg Gly His Glu Val Thr Val 
            20                  25                  30          


Leu Ala Ser Ser Ala Ser Ile Leu Phe Asp Pro Asn Asn Ser Ser Ala 
        35                  40                  45              


Leu Lys Ile Glu Ile Tyr Pro Thr Ser Leu Thr Lys Thr Glu Leu Glu 
    50                  55                  60                  


Asn Phe Ile Met Gln Gln Ile Lys Arg Trp Ser Asp Leu Pro Lys Asp 
65                  70                  75                  80  


Thr Phe Trp Leu Tyr Phe Ser Gln Val Gln Glu Ile Met Ser Ile Phe 
                85                  90                  95      


Gly Asp Ile Thr Arg Lys Phe Cys Lys Asp Val Val Ser Asn Lys Lys 
            100                 105                 110         


Phe Met Lys Lys Val Gln Glu Ser Arg Phe Asp Val Ile Phe Ala Asp 
        115                 120                 125             


Ala Ile Phe Pro Cys Ser Glu Leu Leu Ala Glu Leu Phe Asn Ile Pro 
    130                 135                 140                 


Phe Val Tyr Ser Leu Ser Phe Ser Pro Gly Tyr Thr Phe Glu Lys His 
145                 150                 155                 160 


Ser Gly Gly Phe Ile Phe Pro Pro Ser Tyr Val Pro Val Val Met Ser 
                165                 170                 175     


Glu Leu Thr Asp Gln Met Thr Phe Met Glu Arg Val Lys Asn Met Ile 
            180                 185                 190         


Tyr Val Leu Tyr Phe Asp Phe Trp Phe Glu Ile Phe Asp Met Lys Lys 
        195                 200                 205             


Trp Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu Ser 
    210                 215                 220                 


Glu Thr Met Gly Lys Ala Asp Val Trp Leu Ile Arg Asn Ser Trp Asn 
225                 230                 235                 240 


Phe Gln Phe Pro Tyr Pro Leu Leu Pro Asn Val Asp Phe Val Gly Gly 
                245                 250                 255     


Leu His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Asp Phe 
            260                 265                 270         


Val Gln Ser Ser Gly Glu Asn Gly Val Val Val Phe Ser Leu Gly Ser 
        275                 280                 285             


Met Val Ser Asn Met Thr Glu Glu Arg Ala Asn Val Ile Ala Ser Ala 
    290                 295                 300                 


Leu Ala Gln Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Asn Lys 
305                 310                 315                 320 


Pro Asp Thr Leu Gly Leu Asn Thr Arg Leu Tyr Lys Trp Ile Pro Gln 
                325                 330                 335     


Asn Asp Leu Leu Gly His Pro Lys Thr Arg Ala Phe Ile Thr His Gly 
            340                 345                 350         


Gly Ala Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met Val 
        355                 360                 365             


Gly Ile Pro Leu Phe Ala Asp Gln Pro Asp Asn Ile Ala His Met Lys 
    370                 375                 380                 


Ala Arg Gly Ala Ala Val Arg Val Asp Phe Asn Thr Met Ser Ser Thr 
385                 390                 395                 400 


Asp Leu Leu Asn Ala Leu Lys Arg Val Ile Asn Asp Pro Ser Tyr Lys 
                405                 410                 415     


Glu Asn Val Met Lys Leu Ser Arg Ile Gln His Asp Gln Pro Val Lys 
            420                 425                 430         


Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His Lys 
        435                 440                 445             


Gly Ala Lys His Leu Arg Val Ala Ala His Asp Leu Thr Trp Phe Gln 
    450                 455                 460                 


Tyr His Ser Leu Asp 
465                 


<210>  2113
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  2113

Leu Gln Gln Glu Asp Gly Ile Ser Phe Glu Tyr His Arg Tyr Pro Glu 
1               5                   10                  15      


Leu Arg Glu Ala Leu Val Ser Val Trp Leu Gln Cys Thr Ala Ile Ser 
            20                  25                  30          


Arg Ile Tyr Thr Val Gly Arg Ser Phe Glu Gly Arg Glu Leu Leu Val 
        35                  40                  45              


Ile Glu Leu Ser Asp Asn Pro Gly Val His Glu Pro Gly Glu Pro Glu 
    50                  55                  60                  


Phe Lys Tyr Ile Gly Asn Met His Gly Asn Glu Ala Val Gly Arg Glu 
65                  70                  75                  80  


Leu Leu Ile Phe Leu Ala Gln Tyr Leu Cys Asn Glu Tyr Gln Lys Gly 
                85                  90                  95      


Asn Glu Thr Ile Val Asn Leu Ile His Ser Thr Arg Ile His Ile Met 
            100                 105                 110         


Pro Ser Leu Asn Pro Asp Gly Phe Glu Lys Ala Ala Ser Gln Pro Gly 
        115                 120                 125             


Glu Leu Lys Asp Trp Phe Val Gly Arg Ser Asn Ala Gln Gly Ile Asp 
    130                 135                 140                 


Leu Asn Arg Asn Phe Pro Asp Leu Asp Arg Ile Val Tyr Val Asn Glu 
145                 150                 155                 160 


Lys Glu Gly Gly Pro Asn Asn His Leu Leu Lys Asn Met Lys Lys Ile 
                165                 170                 175     


Val Asp Gln Asn Thr Lys Leu Ala Pro Glu Thr Lys Ala Val Ile His 
            180                 185                 190         


Trp Ile Met Asp Ile Pro Phe Val Leu Ser Ala Asn Leu His Gly Gly 
        195                 200                 205             


Asp Leu Val Ala Asn Tyr Pro Tyr Asp Glu Thr Arg Ser Gly Ser Ala 
    210                 215                 220                 


His Glu Tyr Ser Ser Ser Pro Asp Asp Ala Ile Phe Gln Ser Leu Ala 
225                 230                 235                 240 


Arg Ala Tyr Ser Ser Phe Asn Pro Ala Met Ser Asp Pro Asn Arg Pro 
                245                 250                 255     


Pro Cys Arg Lys Asn Asp Asp Asp Ser Ser Phe Val Asp Gly Thr Thr 
            260                 265                 270         


Asn Gly Gly Ala Trp Tyr Ser Val Pro Gly Gly Met Gln Asp Phe Asn 
        275                 280                 285             


Tyr Leu Ser Ser Asn Cys Phe Glu Ile Thr Val Glu Leu Ser Cys Glu 
    290                 295                 300                 


Lys Phe Pro Pro Glu Glu Thr Leu Lys Thr Tyr Trp Glu Asp Asn Lys 
305                 310                 315                 320 


Asn Ser Leu Ile Ser Tyr Leu Glu Gln Ile His Arg Gly Val Lys Gly 
                325                 330                 335     


Phe Val Arg Asp Leu Gln Gly Asn Pro Ile Ala Asn Ala Thr Ile Ser 
            340                 345                 350         


Val Glu Gly Ile Asp His Asp Val Thr Ser Ala Lys Asp Gly Asp Tyr 
        355                 360                 365             


Trp Arg Leu Leu Ile Pro Gly Asn Tyr Lys Leu Thr Ala Ser Ala Pro 
    370                 375                 380                 


Gly Tyr Leu Ala Ile Thr Lys Lys Val Ala Val Pro Tyr Ser Pro Ala 
385                 390                 395                 400 


Ala Gly Val Asp Phe Glu Leu Glu Ser Phe Ser Glu Arg Lys Glu Glu 
                405                 410                 415     


Glu Lys Glu Glu Leu Met Glu Trp Trp Lys Met Met Ser Glu Thr Leu 
            420                 425                 430         


Asn Phe 
        


<210>  2114
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  2114

Leu Asp Asn Gly Leu Leu Gln Thr Pro Pro Met Gly Trp Leu Ala Trp 
1               5                   10                  15      


Glu Arg Phe Arg Cys Asn Ile Asn Cys Asp Glu Asp Pro Lys Asn Cys 
            20                  25                  30          


Ile Ser Glu Gln Leu Phe Met Glu Met Ala Asp Arg Met Ala Gln Asp 
        35                  40                  45              


Gly Trp Arg Asp Met Gly Tyr Thr Tyr Leu Asn Ile Asp Asp Cys Trp 
    50                  55                  60                  


Ile Gly Gly Arg Asp Ala Ser Gly Arg Leu Met Pro Asp Pro Lys Arg 
65                  70                  75                  80  


Phe Pro His Gly Ile Pro Phe Leu Ala Asp Tyr Val His Ser Leu Gly 
                85                  90                  95      


Leu Lys Leu Gly Ile Tyr Ala Asp Met Gly Asn Phe Thr Cys Met Gly 
            100                 105                 110         


Tyr Pro Gly Thr Thr Leu Asp Lys Val Val Gln Asp Ala Gln Thr Phe 
        115                 120                 125             


Ala Glu Trp Lys Val Asp Met Leu Lys Leu Asp Gly Cys Phe Ser Thr 
    130                 135                 140                 


Pro Glu Glu Arg Ala Gln Gly Tyr Pro Lys Met Ala Ala Ala Leu Asn 
145                 150                 155                 160 


Ala Thr Gly Arg Pro Ile Ala Phe Ser Cys Ser Trp Pro Ala Tyr Glu 
                165                 170                 175     


Gly Gly Leu Pro Pro Arg Val Asn Tyr Ser Leu Leu Ala Asp Ile Cys 
            180                 185                 190         


Asn Leu Trp Arg Asn Tyr Asp Asp Ile Gln Asp Ser Trp Trp Ser Val 
        195                 200                 205             


Leu Ser Ile Leu Asn Trp Phe Val Glu His Gln Asp Ile Leu Gln Pro 
    210                 215                 220                 


Val Ala Gly Pro Gly His Trp Asn Asp Pro Asp Met Leu Leu Ile Gly 
225                 230                 235                 240 


Asn Phe Gly Leu Ser Leu Glu Gln Ser Arg Ala Gln Met Ala Leu Trp 
                245                 250                 255     


Thr Val Leu Ala Ala Pro Leu Leu Met Ser Thr Asp Leu Arg Thr Ile 
            260                 265                 270         


Ser Ala Gln Asn Met Asp Ile Leu Gln Asn Pro Leu Met Ile Lys Ile 
        275                 280                 285             


Asn Gln Asp Pro Leu Gly Ile Gln Gly Arg Arg Ile His Lys Glu Lys 
    290                 295                 300                 


Ser Leu Ile Glu Val Tyr Met Arg Pro Leu Ser Asn Lys Ala Ser Ala 
305                 310                 315                 320 


Leu Val Phe Phe Ser Cys Arg Thr Asp Met Pro Tyr Arg Tyr His Ser 
                325                 330                 335     


Ser Leu Gly Gln Leu Asn Phe Thr Gly Ser Val Ile Tyr Glu Ala Gln 
            340                 345                 350         


Asp Val Tyr Ser Gly Asp Ile Ile Ser Gly Leu Arg Asp Glu Thr Asn 
        355                 360                 365             


Phe Thr Val Ile Ile Asn Pro Ser Gly Val Val Met Trp Tyr Leu Tyr 
    370                 375                 380                 


Pro Ile Lys Asn Leu Glu Met Ser Gln Gln 
385                 390                 


<210>  2115
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  2115

Val Asn Pro Gly Val Val Val Arg Ile Ser Gln Lys Gly Leu Asp Tyr 
1               5                   10                  15      


Ala Ser Gln Gln Gly Thr Ala Ala Leu Gln Lys Glu Leu Lys Arg Ile 
            20                  25                  30          


Lys Ile Pro Asp Tyr Ser Asp Ser Phe Lys Ile Lys His Leu Gly Lys 
        35                  40                  45              


Gly His Tyr Ser Phe Tyr Ser Met Asp Ile Arg Glu Phe Gln Leu Pro 
    50                  55                  60                  


Ser Ser Gln Ile Ser Met Val Pro Asn Val Gly Leu Lys Phe Ser Ile 
65                  70                  75                  80  


Ser Asn Ala Asn Ile Lys Ile Ser Gly Lys Trp Lys Ala Gln Lys Arg 
                85                  90                  95      


Phe Leu Lys Met Ser Gly Asn Phe Asp Leu Ser Ile Glu Gly Met Ser 
            100                 105                 110         


Ile Ser Ala Asp Leu Lys Leu Gly Ser Asn Pro Thr Ser Gly Lys Pro 
        115                 120                 125             


Thr Ile Thr Cys Ser Ser Cys Ser Ser His Ile Asn Ser Val His Val 
    130                 135                 140                 


His Ile Ser Lys Ser Lys Val Gly Trp Leu Ile Gln Leu Phe His Lys 
145                 150                 155                 160 


Lys Ile Glu Ser Ala Leu Arg Asn Lys Met Asn Ser Gln Val Cys Glu 
                165                 170                 175     


Lys Val Thr Asn Ser Val Ser Ser Lys Leu Gln Pro Tyr Phe Gln Thr 
            180                 185                 190         


Leu Pro Val Met Thr Lys Ile Asp Ser Val Ala Gly Ile Asn Tyr Gly 
        195                 200                 205             


Leu Val Ala Pro Pro Ala Thr Thr Ala Glu Thr Leu Asp Val Gln Met 
    210                 215                 220                 


Lys Gly Glu Phe Tyr Ser Glu Asn His His Asn Pro Pro Pro Phe Ala 
225                 230                 235                 240 


Pro Pro Val Met Glu Phe Pro Ala Ala His Asp Arg Met Val Tyr Leu 
                245                 250                 255     


Gly Leu Ser Asp Tyr Phe Phe Asn Thr Ala Gly Leu Val Tyr Gln Glu 
            260                 265                 270         


Ala Gly Val Leu Lys Met Thr Leu Arg Asp Asp Met Ile Pro Lys Glu 
        275                 280                 285             


Ser Lys Phe Arg Leu Thr Thr Lys Phe Phe Gly Thr Phe Leu Pro Glu 
    290                 295                 300                 


Val Ala Lys Lys Phe Pro Asn Met Lys Ile Gln Ile His Val Ser Ala 
305                 310                 315                 320 


Ser Thr Pro Pro His Leu Ser Val Gln Pro Thr Gly Leu Thr Phe Tyr 
                325                 330                 335     


Pro Ala Val Asp Val Gln Ala Phe Ala Val Leu Pro Asn Ser Ser Leu 
            340                 345                 350         


Ala Ser Leu Phe Leu Ile Gly Met His Thr Thr Gly Ser Met Glu Val 
        355                 360                 365             


Ser Ala Glu Ser Asn Arg Leu Val Gly Glu Leu Lys Leu Asp Arg Leu 
    370                 375                 380                 


Leu Leu Glu Leu Lys His Ser Asn Ile Gly Pro Phe Pro Val Glu Leu 
385                 390                 395                 400 


Leu Gln Asp Ile Met Asn Tyr Ile Val Pro Ile Leu Val Leu Pro Arg 
                405                 410                 415     


Val Asn Glu Lys Leu Gln Lys Gly Phe Pro Leu Pro Thr Pro Ala Arg 
            420                 425                 430         


Val Gln Leu Tyr Asn Val Val Leu Gln Pro His Gln Asn Phe Leu Leu 
        435                 440                 445             


Phe Gly Ala Asp Val Val Tyr Lys 
    450                 455     


<210>  2116
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  2116

Thr Asp Thr Glu Glu Arg Leu Val Glu His Leu Leu Asp Pro Ser Arg 
1               5                   10                  15      


Tyr Asn Lys Leu Ile Arg Pro Ala Thr Asn Gly Ser Glu Leu Val Thr 
            20                  25                  30          


Val Gln Leu Met Val Ser Leu Ala Gln Leu Ile Ser Val His Glu Arg 
        35                  40                  45              


Glu Gln Ile Met Thr Thr Asn Val Trp Leu Thr Gln Glu Trp Glu Asp 
    50                  55                  60                  


Tyr Arg Leu Thr Trp Lys Pro Glu Glu Phe Asp Asn Met Lys Lys Val 
65                  70                  75                  80  


Arg Leu Pro Ser Lys His Ile Trp Leu Pro Asp Val Val Leu Tyr Asn 
                85                  90                  95      


Asn Ala Asp Gly Met Tyr Glu Val Ser Phe Tyr Ser Asn Ala Val Val 
            100                 105                 110         


Ser Tyr Asp Gly Ser Ile Phe Trp Leu Pro Pro Ala Ile Tyr Lys Ser 
        115                 120                 125             


Ala Cys Lys Ile Glu Val Lys His Phe Pro Phe Asp Gln Gln Asn Cys 
    130                 135                 140                 


Thr Met Lys Phe Arg Ser Trp Thr Tyr Asp Arg Thr Glu Ile Asp Leu 
145                 150                 155                 160 


Val Leu Lys Ser Glu Val Ala Ser Leu Asp Asp Phe Thr Pro Ser Gly 
                165                 170                 175     


Glu Trp Asp Ile Val Ala Leu Pro Gly Arg Arg Asn Glu Asn Pro Asp 
            180                 185                 190         


Asp Ser Thr Tyr Val Asp Ile Thr Tyr Asp Phe Ile Ile Arg Arg Lys 
        195                 200                 205             


<210>  2117
<211>  561
<212>  PRT
<213>  Homo Sapiens

<400>  2117

Glu Thr Val His Cys Asp Leu Gln Pro Val Gly Pro Glu Arg Asp Glu 
1               5                   10                  15      


Val Thr Tyr Thr Thr Ser Gln Val Ser Lys Gly Cys Val Ala Gln Ala 
            20                  25                  30          


Pro Asn Ala Ile Leu Glu Val His Val Leu Phe Leu Glu Phe Pro Thr 
        35                  40                  45              


Gly Pro Ser Gln Leu Glu Leu Thr Leu Gln Ala Ser Lys Gln Asn Gly 
    50                  55                  60                  


Thr Trp Pro Arg Glu Val Leu Leu Val Leu Ser Val Asn Ser Ser Val 
65                  70                  75                  80  


Phe Leu His Leu Gln Ala Leu Gly Ile Pro Leu His Leu Ala Tyr Asn 
                85                  90                  95      


Ser Ser Leu Val Thr Phe Gln Glu Pro Pro Gly Val Asn Thr Thr Glu 
            100                 105                 110         


Leu Pro Ser Phe Pro Lys Thr Gln Ile Leu Glu Trp Ala Ala Glu Arg 
        115                 120                 125             


Gly Pro Ile Thr Ser Ala Ala Glu Leu Asn Asp Pro Gln Ser Ile Leu 
    130                 135                 140                 


Leu Arg Leu Gly Gln Ala Gln Gly Ser Leu Ser Phe Cys Met Leu Glu 
145                 150                 155                 160 


Ala Ser Gln Asp Met Gly Arg Thr Leu Glu Trp Arg Pro Arg Thr Pro 
                165                 170                 175     


Ala Leu Val Arg Gly Cys His Leu Glu Gly Val Ala Gly His Lys Glu 
            180                 185                 190         


Ala His Ile Leu Arg Val Leu Pro Gly His Ser Ala Gly Pro Arg Thr 
        195                 200                 205             


Val Thr Val Lys Val Glu Leu Ser Cys Ala Pro Gly Asp Leu Asp Ala 
    210                 215                 220                 


Val Leu Ile Leu Gln Gly Pro Pro Tyr Val Ser Trp Leu Ile Asp Ala 
225                 230                 235                 240 


Asn His Asn Met Gln Ile Trp Thr Thr Gly Glu Tyr Ser Phe Lys Ile 
                245                 250                 255     


Phe Pro Glu Lys Asn Ile Arg Gly Phe Lys Leu Pro Asp Thr Pro Gln 
            260                 265                 270         


Gly Leu Leu Gly Glu Ala Arg Met Leu Asn Ala Ser Ile Val Ala Ser 
        275                 280                 285             


Phe Val Glu Leu Pro Leu Ala Ser Ile Val Ser Leu His Ala Ser Ser 
    290                 295                 300                 


Cys Gly Gly Arg Leu Gln Thr Ser Pro Ala Pro Ile Gln Thr Thr Pro 
305                 310                 315                 320 


Pro Lys Asp Thr Cys Ser Pro Glu Leu Leu Met Ser Leu Ile Gln Thr 
                325                 330                 335     


Lys Cys Ala Asp Asp Ala Met Thr Leu Val Leu Lys Lys Glu Leu Val 
            340                 345                 350         


Ala His Leu Lys Cys Thr Ile Thr Gly Leu Thr Phe Trp Asp Pro Ser 
        355                 360                 365             


Cys Glu Ala Glu Asp Arg Gly Asp Lys Phe Val Leu Arg Ser Ala Tyr 
    370                 375                 380                 


Ser Ser Cys Gly Met Gln Val Ser Ala Ser Met Ile Ser Asn Glu Ala 
385                 390                 395                 400 


Val Val Asn Ile Leu Ser Ser Ser Ser Pro Gln Arg Lys Lys Val His 
                405                 410                 415     


Cys Leu Asn Met Asp Ser Leu Ser Phe Gln Leu Gly Leu Tyr Leu Ser 
            420                 425                 430         


Pro His Phe Leu Gln Ala Ser Asn Thr Ile Glu Pro Gly Gln Gln Ser 
        435                 440                 445             


Phe Val Gln Val Arg Val Ser Pro Ser Val Ser Glu Phe Leu Leu Gln 
    450                 455                 460                 


Leu Asp Ser Cys His Leu Asp Leu Gly Pro Glu Gly Gly Thr Val Glu 
465                 470                 475                 480 


Leu Ile Gln Gly Arg Ala Ala Lys Gly Asn Cys Val Ser Leu Leu Ser 
                485                 490                 495     


Pro Ser Pro Glu Gly Asp Pro Arg Phe Ser Phe Leu Leu His Phe Tyr 
            500                 505                 510         


Thr Val Pro Ile Pro Lys Thr Gly Thr Leu Ser Cys Thr Val Ala Leu 
        515                 520                 525             


Arg Pro Lys Thr Gly Ser Gln Asp Gln Glu Val His Arg Thr Val Phe 
    530                 535                 540                 


Met Arg Leu Asn Ile Ile Ser Pro Asp Leu Ser Gly Cys Thr Ser Lys 
545                 550                 555                 560 


Gly 
    


<210>  2118
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2118

Ser Ser Phe Ser Trp Asp Asn Cys Asp Glu Gly Lys Asp Pro Ala Val 
1               5                   10                  15      


Ile Arg Ser Leu Thr Leu Glu Pro Asp Pro Ile Val Val Pro Gly Asn 
            20                  25                  30          


Val Thr Leu Ser Val Val Gly Ser Thr Ser Val Pro Leu Ser Ser Pro 
        35                  40                  45              


Leu Lys Val Asp Leu Val Leu Glu Lys Glu Val Ala Gly Leu Trp Ile 
    50                  55                  60                  


Lys Ile Pro Cys Thr Asp Tyr Ile Gly Ser Cys Thr Phe Glu His Phe 
65                  70                  75                  80  


Cys Asp Val Leu Asp Met Leu Ile Pro Thr Gly Glu Pro Cys Pro Glu 
                85                  90                  95      


Pro Leu Arg Thr Tyr Gly Leu Pro Cys His Cys Pro Phe Lys Glu Gly 
            100                 105                 110         


Thr Tyr Ser Leu Pro Lys Ser Glu Phe Val Val Pro Asp Leu Glu Leu 
        115                 120                 125             


Pro Ser Trp Leu Thr Thr Gly Asn Tyr Arg Ile Glu Ser Val Leu Ser 
    130                 135                 140                 


Ser Ser Gly Lys Arg Leu Gly Cys Ile Lys Ile Ala Ala Ser Leu Lys 
145                 150                 155                 160 


Gly Ile 
        


<210>  2119
<211>  249
<212>  PRT
<213>  Homo Sapiens

<400>  2119

Ala Asp Asn Phe Ser Leu His Asp Ala Leu Ser Gly Ser Gly Asn Pro 
1               5                   10                  15      


Asn Pro Gln Gly Trp Pro Gly Ala Trp Gly Asn Gln Pro Ala Gly Ala 
            20                  25                  30          


Gly Gly Tyr Pro Gly Ala Ser Tyr Pro Gly Ala Tyr Pro Gly Gln Ala 
        35                  40                  45              


Pro Pro Gly Ala Tyr Pro Gly Gln Ala Pro Pro Gly Ala Tyr Pro Gly 
    50                  55                  60                  


Ala Pro Gly Ala Tyr Pro Gly Ala Pro Ala Pro Gly Val Tyr Pro Gly 
65                  70                  75                  80  


Pro Pro Ser Gly Pro Gly Ala Tyr Pro Ser Ser Gly Gln Pro Ser Ala 
                85                  90                  95      


Thr Gly Ala Tyr Pro Ala Thr Gly Pro Tyr Gly Ala Pro Ala Gly Pro 
            100                 105                 110         


Leu Ile Val Pro Tyr Asn Leu Pro Leu Pro Gly Gly Val Val Pro Arg 
        115                 120                 125             


Met Leu Ile Thr Ile Leu Gly Thr Val Lys Pro Asn Ala Asn Arg Ile 
    130                 135                 140                 


Ala Leu Asp Phe Gln Arg Gly Asn Asp Val Ala Phe His Phe Asn Pro 
145                 150                 155                 160 


Arg Phe Asn Glu Asn Asn Arg Arg Val Ile Val Cys Asn Thr Lys Leu 
                165                 170                 175     


Asp Asn Asn Trp Gly Arg Glu Glu Arg Gln Ser Val Phe Pro Phe Glu 
            180                 185                 190         


Ser Gly Lys Pro Phe Lys Ile Gln Val Leu Val Glu Pro Asp His Phe 
        195                 200                 205             


Lys Val Ala Val Asn Asp Ala His Leu Leu Gln Tyr Asn His Arg Val 
    210                 215                 220                 


Lys Lys Leu Asn Glu Ile Ser Lys Leu Gly Ile Ser Gly Asp Ile Asp 
225                 230                 235                 240 


Leu Thr Ser Ala Ser Tyr Thr Met Ile 
                245                 


<210>  2120
<211>  264
<212>  PRT
<213>  Homo Sapiens

<400>  2120

Gly Ala Ser Ser Gly Gly Leu Gly Pro Val Val Arg Cys Glu Pro Cys 
1               5                   10                  15      


Asp Ala Arg Ala Leu Ala Gln Cys Ala Pro Pro Pro Ala Val Cys Ala 
            20                  25                  30          


Glu Leu Val Arg Glu Pro Gly Cys Gly Cys Cys Leu Thr Cys Ala Leu 
        35                  40                  45              


Ser Glu Gly Gln Pro Cys Gly Ile Tyr Thr Glu Arg Cys Gly Ser Gly 
    50                  55                  60                  


Leu Arg Cys Gln Pro Ser Pro Asp Glu Ala Arg Pro Leu Gln Ala Leu 
65                  70                  75                  80  


Leu Asp Gly Arg Gly Leu Cys Val Asn Ala Ser Ala Val Ser Arg Leu 
                85                  90                  95      


Arg Ala Tyr Leu Leu Pro Ala Pro Pro Ala Pro Gly Asn Ala Ser Glu 
            100                 105                 110         


Ser Glu Glu Asp Arg Ser Ala Gly Ser Val Glu Ser Pro Ser Val Ser 
        115                 120                 125             


Ser Thr His Arg Val Ser Asp Pro Lys Phe His Pro Leu His Ser Lys 
    130                 135                 140                 


Ile Ile Ile Ile Lys Lys Gly His Ala Lys Asp Ser Gln Arg Tyr Lys 
145                 150                 155                 160 


Val Asp Tyr Glu Ser Gln Ser Thr Asp Thr Gln Asn Phe Ser Ser Glu 
                165                 170                 175     


Ser Lys Arg Glu Thr Glu Tyr Gly Pro Cys Arg Arg Glu Met Glu Asp 
            180                 185                 190         


Thr Leu Asn His Leu Lys Phe Leu Asn Val Leu Ser Pro Arg Gly Val 
        195                 200                 205             


His Ile Pro Asn Cys Asp Lys Lys Gly Phe Tyr Lys Lys Lys Gln Cys 
    210                 215                 220                 


Arg Pro Ser Lys Gly Arg Lys Arg Gly Phe Cys Trp Cys Val Asp Lys 
225                 230                 235                 240 


Tyr Gly Gln Pro Leu Pro Gly Tyr Thr Thr Lys Gly Lys Glu Asp Val 
                245                 250                 255     


His Cys Tyr Ser Met Gln Ser Lys 
            260                 


<210>  2121
<211>  290
<212>  PRT
<213>  Homo Sapiens

<400>  2121

Ala Glu Val Leu Phe Arg Cys Pro Pro Cys Thr Pro Glu Arg Leu Ala 
1               5                   10                  15      


Ala Cys Gly Pro Pro Pro Val Ala Pro Pro Ala Ala Val Ala Ala Val 
            20                  25                  30          


Ala Gly Gly Ala Arg Met Pro Cys Ala Glu Leu Val Arg Glu Pro Gly 
        35                  40                  45              


Cys Gly Cys Cys Ser Val Cys Ala Arg Leu Glu Gly Glu Ala Cys Gly 
    50                  55                  60                  


Val Tyr Thr Pro Arg Cys Gly Gln Gly Leu Arg Cys Tyr Pro His Pro 
65                  70                  75                  80  


Gly Ser Glu Leu Pro Leu Gln Ala Leu Val Met Gly Glu Gly Thr Cys 
                85                  90                  95      


Glu Lys Arg Arg Asp Ala Glu Tyr Gly Ala Ser Pro Glu Gln Val Ala 
            100                 105                 110         


Asp Asn Gly Asp Asp His Ser Glu Gly Gly Leu Val Glu Asn His Val 
        115                 120                 125             


Asp Ser Thr Met Asn Met Leu Gly Gly Gly Gly Ser Ala Gly Arg Lys 
    130                 135                 140                 


Pro Leu Lys Ser Gly Met Lys Glu Leu Ala Val Phe Arg Glu Lys Val 
145                 150                 155                 160 


Thr Glu Gln His Arg Gln Met Gly Lys Gly Gly Lys His His Leu Gly 
                165                 170                 175     


Leu Glu Glu Pro Lys Lys Leu Arg Pro Pro Pro Ala Arg Thr Pro Cys 
            180                 185                 190         


Gln Gln Glu Leu Asp Gln Val Leu Glu Arg Ile Ser Thr Met Arg Leu 
        195                 200                 205             


Pro Asp Glu Arg Gly Pro Leu Glu His Leu Tyr Ser Leu His Ile Pro 
    210                 215                 220                 


Asn Cys Asp Lys His Gly Leu Tyr Asn Leu Lys Gln Cys Lys Met Ser 
225                 230                 235                 240 


Leu Asn Gly Gln Arg Gly Glu Cys Trp Cys Val Asn Pro Asn Thr Gly 
                245                 250                 255     


Lys Leu Ile Gln Gly Ala Pro Thr Ile Arg Gly Asp Pro Glu Cys His 
            260                 265                 270         


Leu Phe Tyr Asn Glu Gln Gln Glu Ala Arg Gly Val His Thr Gln Arg 
        275                 280                 285             


Met Gln 
    290 


<210>  2122
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2122

Asn Asn Ala Thr Thr Val Ala Pro Ser Val Gly Ile Thr Arg Leu Ile 
1               5                   10                  15      


Asn Ser Ser Thr Ala Glu Pro Val Lys Glu Glu Ala Lys Thr Ser Asn 
            20                  25                  30          


Pro Thr Ser Ser Leu Thr Ser Leu Ser Val Ala Pro Thr Phe Ser Pro 
        35                  40                  45              


Asn Ile Thr Leu Gly Pro Thr Tyr Leu Thr Thr Val Asn Ser Ser Asp 
    50                  55                  60                  


Ser Asp Asn Gly Thr Thr Arg Thr Ala Ser Thr Asn Ser Ile Gly Ile 
65                  70                  75                  80  


Thr Ile Ser Pro Asn Gly Thr Trp Leu Pro Asp Asn Gln Phe Thr Asp 
                85                  90                  95      


Ala Arg Thr Glu Pro Trp Glu Gly Asn Ser Ser Thr Ala Ala Thr Thr 
            100                 105                 110         


Pro Glu Thr Phe Pro Pro Ser Asp Glu Thr Pro 
        115                 120             


<210>  2123
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  2123

His Ser Thr Asn Glu Pro Ser Asn Met Ser Tyr Val Lys Glu Thr Val 
1               5                   10                  15      


Asp Arg Leu Leu Lys Gly Tyr Asp Ile Arg Leu Arg Pro Asp Phe Gly 
            20                  25                  30          


Gly Pro Pro Val Asp Val Gly Met Arg Ile Asp Val Ala Ser Ile Asp 
        35                  40                  45              


Met Val Ser Glu Val Asn Met Asp Tyr Thr Leu Thr Met Tyr Phe Gln 
    50                  55                  60                  


Gln Ser Trp Lys Asp Lys Arg Leu Ser Tyr Ser Gly Ile Pro Leu Asn 
65                  70                  75                  80  


Leu Thr Leu Asp Asn Arg Val Ala Asp Gln Leu Cys Val Pro Asp Thr 
                85                  90                  95      


Tyr Phe Leu Asn Asp Lys Lys Ser Phe Val His Gly Val Thr Val Lys 
            100                 105                 110         


Asn Arg Met Ile Arg Leu His Pro Asp Gly Thr Val Leu Tyr Gly Leu 
        115                 120                 125             


Arg Ile Thr Thr Thr Ala Ala Cys Met Met Asp Leu Arg Arg Tyr Pro 
    130                 135                 140                 


Leu Asp Glu Gln Asn Cys Thr Leu Glu Ile Glu Ser Tyr Gly Tyr Thr 
145                 150                 155                 160 


Thr Asp Asp Ile Glu Phe Tyr Trp Asn Gly Gly Glu Gly Ala Val Thr 
                165                 170                 175     


Gly Val Asn Lys Ile Glu Leu Pro Gln Phe Ser Ile Val Asp Tyr Lys 
            180                 185                 190         


Met Val Ser Lys Lys Val Glu Phe Thr Thr Gly Ala Tyr Pro Arg Leu 
        195                 200                 205             


Ser Leu Ser Phe Arg Leu Lys Arg Asn Ile Gly Tyr 
    210                 215                 220 


<210>  2124
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2124

Gln Lys Ser Asp Asp Asp Tyr Glu Asp Tyr Ala Ser Asn Lys Thr Trp 
1               5                   10                  15      


Val Leu Thr Pro Lys Val Pro Glu Gly Asp Val Thr Val Ile Leu Asn 
            20                  25                  30          


Asn Leu Leu Glu Gly Tyr Asp Asn Lys Leu Arg Pro Asp Ile Gly Val 
        35                  40                  45              


Lys Pro Thr Leu Ile His Thr Asp Met Tyr Val Asn Ser Ile Gly Pro 
    50                  55                  60                  


Val Asn Ala Ile Asn Met Glu Tyr Thr Ile Asp Ile Phe Phe Ala Gln 
65                  70                  75                  80  


Thr Trp Tyr Asp Arg Arg Leu Lys Phe Asn Ser Thr Ile Lys Val Leu 
                85                  90                  95      


Arg Leu Asn Ser Asn Met Val Gly Lys Ile Trp Ile Pro Asp Thr Phe 
            100                 105                 110         


Phe Arg Asn Ser Lys Lys Ala Asp Ala His Trp Ile Thr Thr Pro Asn 
        115                 120                 125             


Arg Met Leu Arg Ile Trp Asn Asp Gly Arg Val Leu Tyr Thr Leu Arg 
    130                 135                 140                 


Leu Thr Ile Asp Ala Glu Cys Gln Leu Gln Leu His Asn Phe Pro Met 
145                 150                 155                 160 


Asp Glu His Ser Cys Pro Leu Glu Phe Ser Ser Tyr Gly Tyr Pro Arg 
                165                 170                 175     


Glu Glu Ile Val Tyr Gln Trp Lys Arg Ser Ser Val Glu Val Gly Asp 
            180                 185                 190         


Thr Arg Ser Trp Arg Leu Tyr Gln Phe Ser Phe Val Gly Leu Arg Asn 
        195                 200                 205             


Thr Thr Glu Val Val Lys Thr Thr Ser Gly Asp Tyr Val Val Met Ser 
    210                 215                 220                 


Val Tyr Phe Asp Leu Ser Arg Arg Met Gly 
225                 230                 


<210>  2125
<211>  48
<212>  PRT
<213>  Homo Sapiens

<400>  2125

Asp Val Ala His Gly Ile Leu Asn Glu Ala Tyr Arg Lys Val Leu Asp 
1               5                   10                  15      


Gln Leu Ser Ala Gly Lys His Leu Gln Ser Leu Val Ala Arg Gly Val 
            20                  25                  30          


Gly Gly Ser Leu Gly Gly Gly Ala Gly Asp Asp Ala Glu Pro Leu Ser 
        35                  40                  45              


<210>  2126
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  2126

Asp Lys Leu Leu Val Val Pro Gln Asp Gly Ser His Trp Leu Ser Met 
1               5                   10                  15      


Lys Asp Ile Val Glu Val Leu Ser Asp Arg Gly His Glu Ile Val Val 
            20                  25                  30          


Val Val Pro Glu Val Asn Leu Leu Leu Lys Glu Ser Lys Tyr Tyr Thr 
        35                  40                  45              


Arg Lys Ile Tyr Pro Val Pro Tyr Asp Gln Glu Glu Leu Lys Asn Arg 
    50                  55                  60                  


Tyr Gln Ser Phe Gly Asn Asn His Phe Ala Glu Arg Ser Phe Leu Thr 
65                  70                  75                  80  


Ala Pro Gln Thr Glu Tyr Arg Asn Asn Met Ile Val Ile Gly Leu Tyr 
                85                  90                  95      


Phe Ile Asn Cys Gln Ser Leu Leu Gln Asp Arg Asp Thr Leu Asn Phe 
            100                 105                 110         


Phe Lys Glu Ser Lys Phe Asp Ala Leu Phe Thr Asp Pro Ala Leu Pro 
        115                 120                 125             


Cys Gly Val Ile Leu Ala Glu Tyr Leu Gly Leu Pro Ser Val Tyr Leu 
    130                 135                 140                 


Phe Arg Gly Phe Pro Cys Ser Leu Glu His Thr Phe Ser Arg Ser Pro 
145                 150                 155                 160 


Asp Pro Val Ser Tyr Ile Pro Arg Cys Tyr Thr Lys Phe Ser Asp His 
                165                 170                 175     


Met Thr Phe Ser Gln Arg Val Ala Asn Phe Leu Val Asn Leu Leu Glu 
            180                 185                 190         


Pro Tyr Leu Phe Tyr Cys Leu Phe Ser Lys Tyr Glu Glu Leu Ala Ser 
        195                 200                 205             


Ala Val Leu Lys Arg Asp Val Asp Ile Ile Thr Leu Tyr Gln Lys Val 
    210                 215                 220                 


Ser Val Trp Leu Leu Arg Tyr Asp Phe Val Leu Glu Tyr Pro Arg Pro 
225                 230                 235                 240 


Val Met Pro Asn Met Val Phe Ile Gly Gly Ile Asn Cys Lys Lys Arg 
                245                 250                 255     


Lys Asp Leu Ser Gln Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu 
            260                 265                 270         


His Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro 
        275                 280                 285             


Glu Lys Lys Ala Met Ala Thr Ala Asp Ala Leu Gly Lys Ile Pro Gln 
    290                 295                 300                 


Thr Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn 
305                 310                 315                 320 


Asn Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His 
                325                 330                 335     


Pro Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr 
            340                 345                 350         


Glu Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly 
        355                 360                 365             


Asp Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val 
    370                 375                 380                 


Thr Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu 
385                 390                 395                 400 


Lys Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu 
                405                 410                 415     


Ser Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val 
            420                 425                 430         


Phe Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg 
        435                 440                 445             


Pro Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460             


<210>  2127
<211>  543
<212>  PRT
<213>  Homo Sapiens

<400>  2127

Pro Ser Ala Ser Lys Glu Pro Asp Asn His Val Tyr Thr Arg Ala Ala 
1               5                   10                  15      


Val Ala Ala Asp Ala Lys Gln Cys Ser Lys Ile Gly Arg Asp Ala Leu 
            20                  25                  30          


Arg Asp Gly Gly Ser Ala Val Asp Ala Ala Ile Ala Ala Leu Leu Cys 
        35                  40                  45              


Val Gly Leu Met Asn Ala His Ser Met Gly Ile Gly Gly Gly Leu Phe 
    50                  55                  60                  


Leu Thr Ile Tyr Asn Ser Thr Thr Arg Lys Ala Glu Val Ile Asn Ala 
65                  70                  75                  80  


Arg Glu Val Ala Pro Arg Leu Ala Phe Ala Thr Met Phe Asn Ser Ser 
                85                  90                  95      


Glu Gln Ser Gln Lys Gly Gly Leu Ser Val Ala Val Pro Gly Glu Ile 
            100                 105                 110         


Arg Gly Tyr Glu Leu Ala His Gln Arg His Gly Arg Leu Pro Trp Ala 
        115                 120                 125             


Arg Leu Phe Gln Pro Ser Ile Gln Leu Ala Arg Gln Gly Phe Pro Val 
    130                 135                 140                 


Gly Lys Gly Leu Ala Ala Ala Leu Glu Asn Lys Arg Thr Val Ile Glu 
145                 150                 155                 160 


Gln Gln Pro Val Leu Cys Glu Val Phe Cys Arg Asp Arg Lys Val Leu 
                165                 170                 175     


Arg Glu Gly Glu Arg Leu Thr Leu Pro Gln Leu Ala Asp Thr Tyr Glu 
            180                 185                 190         


Thr Leu Ala Ile Glu Gly Ala Gln Ala Phe Tyr Asn Gly Ser Leu Thr 
        195                 200                 205             


Ala Gln Ile Val Lys Asp Ile Gln Ala Ala Gly Gly Ile Val Thr Ala 
    210                 215                 220                 


Glu Asp Leu Asn Asn Tyr Arg Ala Glu Leu Ile Glu His Pro Leu Asn 
225                 230                 235                 240 


Ile Ser Leu Gly Asp Val Val Leu Tyr Met Pro Ser Ala Pro Leu Ser 
                245                 250                 255     


Gly Pro Val Leu Ala Leu Ile Leu Asn Ile Leu Lys Gly Tyr Asn Phe 
            260                 265                 270         


Ser Arg Glu Ser Val Glu Ser Pro Glu Gln Lys Gly Leu Thr Tyr His 
        275                 280                 285             


Arg Ile Val Glu Ala Phe Arg Phe Ala Tyr Ala Lys Arg Thr Leu Leu 
    290                 295                 300                 


Gly Asp Pro Lys Phe Val Asp Val Thr Glu Val Val Arg Asn Met Thr 
305                 310                 315                 320 


Ser Glu Phe Phe Ala Ala Gln Leu Arg Ala Gln Ile Ser Asp Asp Thr 
                325                 330                 335     


Thr His Pro Ile Ser Tyr Tyr Lys Pro Glu Phe Tyr Thr Pro Asp Asp 
            340                 345                 350         


Gly Gly Thr Ala His Leu Ser Val Val Ala Glu Asp Gly Ser Ala Val 
        355                 360                 365             


Ser Ala Thr Ser Thr Ile Asn Leu Tyr Phe Gly Ser Lys Val Arg Ser 
    370                 375                 380                 


Pro Val Ser Gly Ile Leu Phe Asn Asn Glu Met Asp Asp Phe Ser Ser 
385                 390                 395                 400 


Pro Ser Ile Thr Asn Glu Phe Gly Val Pro Pro Ser Pro Ala Asn Phe 
                405                 410                 415     


Ile Gln Pro Gly Lys Gln Pro Leu Ser Ser Met Cys Pro Thr Ile Met 
            420                 425                 430         


Val Gly Gln Asp Gly Gln Val Arg Met Val Val Gly Ala Ala Gly Gly 
        435                 440                 445             


Thr Gln Ile Thr Thr Ala Thr Ala Leu Ala Ile Ile Tyr Asn Leu Trp 
    450                 455                 460                 


Phe Gly Tyr Asp Val Lys Arg Ala Val Glu Glu Pro Arg Leu His Asn 
465                 470                 475                 480 


Gln Leu Leu Pro Asn Val Thr Thr Val Glu Arg Asn Ile Asp Gln Ala 
                485                 490                 495     


Val Thr Ala Ala Leu Glu Thr Arg His His His Thr Gln Ile Ala Ser 
            500                 505                 510         


Thr Phe Ile Ala Val Val Gln Ala Ile Val Arg Thr Ala Gly Gly Trp 
        515                 520                 525             


Ala Ala Ala Ser Asp Ser Arg Lys Gly Gly Glu Pro Ala Gly Tyr 
    530                 535                 540             


<210>  2128
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2128

Gln Ile Pro Leu Cys Ala Asn Leu Val Pro Val Pro Ile Thr Asn Ala 
1               5                   10                  15      


Thr Leu Asp Arg Ile Thr Gly Lys Trp Phe Tyr Ile Ala Ser Ala Phe 
            20                  25                  30          


Arg Asn Glu Glu Tyr Asn Lys Ser Val Gln Glu Ile Gln Ala Thr Phe 
        35                  40                  45              


Phe Tyr Phe Thr Pro Asn Lys Thr Glu Asp Thr Ile Phe Leu Arg Glu 
    50                  55                  60                  


Tyr Gln Thr Arg Gln Asn Gln Cys Phe Tyr Asn Ser Ser Tyr Leu Asn 
65                  70                  75                  80  


Val Gln Arg Glu Asn Gly Thr Val Ser Arg Tyr Glu Gly Gly Arg Glu 
                85                  90                  95      


His Val Ala His Leu Leu Phe Leu Arg Asp Thr Lys Thr Leu Met Phe 
            100                 105                 110         


Gly Ser Tyr Leu Asp Asp Glu Lys Asn Trp Gly Leu Ser Phe Tyr Ala 
        115                 120                 125             


Asp Lys Pro Glu Thr Thr Lys Glu Gln Leu Gly Glu Phe Tyr Glu Ala 
    130                 135                 140                 


Leu Asp Cys Leu Cys Ile Pro Arg Ser Asp Val Met Tyr Thr Asp Trp 
145                 150                 155                 160 


Lys Lys Asp Lys Cys Glu Pro Leu Glu Lys Gln His Glu Lys Glu Arg 
                165                 170                 175     


Lys Gln Glu Glu Gly Glu Ser 
            180             


<210>  2129
<211>  315
<212>  PRT
<213>  Homo Sapiens

<400>  2129

Gly Asn Cys Trp Leu Arg Gln Ala Lys Asn Gly Arg Cys Gln Val Leu 
1               5                   10                  15      


Tyr Lys Thr Glu Leu Ser Lys Glu Glu Cys Cys Ser Thr Gly Arg Leu 
            20                  25                  30          


Ser Thr Ser Trp Thr Glu Glu Asp Val Asn Asp Asn Thr Leu Phe Lys 
        35                  40                  45              


Trp Met Ile Phe Asn Gly Gly Ala Pro Asn Cys Ile Pro Cys Lys Glu 
    50                  55                  60                  


Thr Cys Glu Asn Val Asp Cys Gly Pro Gly Lys Lys Cys Arg Met Asn 
65                  70                  75                  80  


Lys Lys Asn Lys Pro Arg Cys Val Cys Ala Pro Asp Cys Ser Asn Ile 
                85                  90                  95      


Thr Trp Lys Gly Pro Val Cys Gly Leu Asp Gly Lys Thr Tyr Arg Asn 
            100                 105                 110         


Glu Cys Ala Leu Leu Lys Ala Arg Cys Lys Glu Gln Pro Glu Leu Glu 
        115                 120                 125             


Val Gln Tyr Gln Gly Arg Cys Lys Lys Thr Cys Arg Asp Val Phe Cys 
    130                 135                 140                 


Pro Gly Ser Ser Thr Cys Val Val Asp Gln Thr Asn Asn Ala Tyr Cys 
145                 150                 155                 160 


Val Thr Cys Asn Arg Ile Cys Pro Glu Pro Ala Ser Ser Glu Gln Tyr 
                165                 170                 175     


Leu Cys Gly Asn Asp Gly Val Thr Tyr Ser Ser Ala Cys His Leu Arg 
            180                 185                 190         


Lys Ala Thr Cys Leu Leu Gly Arg Ser Ile Gly Leu Ala Tyr Glu Gly 
        195                 200                 205             


Lys Cys Ile Lys Ala Lys Ser Cys Glu Asp Ile Gln Cys Thr Gly Gly 
    210                 215                 220                 


Lys Lys Cys Leu Trp Asp Phe Lys Val Gly Arg Gly Arg Cys Ser Leu 
225                 230                 235                 240 


Cys Asp Glu Leu Cys Pro Asp Ser Lys Ser Asp Glu Pro Val Cys Ala 
                245                 250                 255     


Ser Asp Asn Ala Thr Tyr Ala Ser Glu Cys Ala Met Lys Glu Ala Ala 
            260                 265                 270         


Cys Ser Ser Gly Val Leu Leu Glu Val Lys His Ser Gly Ser Cys Asn 
        275                 280                 285             


Ser Ile Ser Glu Asp Thr Glu Glu Glu Glu Glu Asp Glu Asp Gln Asp 
    290                 295                 300                 


Tyr Ser Phe Pro Ile Ser Ser Ile Leu Glu Trp 
305                 310                 315 


<210>  2130
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2130

Ala Gln Glu Pro Val Lys Gly Pro Val Ser Thr Lys Pro Gly Ser Cys 
1               5                   10                  15      


Pro Ile Ile Leu Ile Arg Cys Ala Met Leu Asn Pro Pro Asn Arg Cys 
            20                  25                  30          


Leu Lys Asp Thr Asp Cys Pro Gly Ile Lys Lys Cys Cys Glu Gly Ser 
        35                  40                  45              


Cys Gly Met Ala Cys Phe Val Pro Gln 
    50                  55          


<210>  2131
<211>  1010
<212>  PRT
<213>  Homo Sapiens

<400>  2131

Ile Ser Cys Gly Ser Pro Pro Pro Ile Leu Asn Gly Arg Ile Ser Tyr 
1               5                   10                  15      


Tyr Ser Thr Pro Ile Ala Val Gly Thr Val Ile Arg Tyr Ser Cys Ser 
            20                  25                  30          


Gly Thr Phe Arg Leu Ile Gly Glu Lys Ser Leu Leu Cys Ile Thr Lys 
        35                  40                  45              


Asp Lys Val Asp Gly Thr Trp Asp Lys Pro Ala Pro Lys Cys Glu Tyr 
    50                  55                  60                  


Phe Asn Lys Tyr Ser Ser Cys Pro Glu Pro Ile Val Pro Gly Gly Tyr 
65                  70                  75                  80  


Lys Ile Arg Gly Ser Thr Pro Tyr Arg His Gly Asp Ser Val Thr Phe 
                85                  90                  95      


Ala Cys Lys Thr Asn Phe Ser Met Asn Gly Asn Lys Ser Val Trp Cys 
            100                 105                 110         


Gln Ala Asn Asn Met Trp Gly Pro Thr Arg Leu Pro Thr Cys Val Ser 
        115                 120                 125             


Val Phe Pro Leu Glu Cys Pro Ala Leu Pro Met Ile His Asn Gly His 
    130                 135                 140                 


His Thr Ser Glu Asn Val Gly Ser Ile Ala Pro Gly Leu Ser Val Thr 
145                 150                 155                 160 


Tyr Ser Cys Glu Ser Gly Tyr Leu Leu Val Gly Glu Lys Ile Ile Asn 
                165                 170                 175     


Cys Leu Ser Ser Gly Lys Trp Ser Ala Val Pro Pro Thr Cys Glu Glu 
            180                 185                 190         


Ala Arg Cys Lys Ser Leu Gly Arg Phe Pro Asn Gly Lys Val Lys Glu 
        195                 200                 205             


Pro Pro Ile Leu Arg Val Gly Val Thr Ala Asn Phe Phe Cys Asp Glu 
    210                 215                 220                 


Gly Tyr Arg Leu Gln Gly Pro Pro Ser Ser Arg Cys Val Ile Ala Gly 
225                 230                 235                 240 


Gln Gly Val Ala Trp Thr Lys Met Pro Val Cys Glu Glu Ile Phe Cys 
                245                 250                 255     


Pro Ser Pro Pro Pro Ile Leu Asn Gly Arg His Ile Gly Asn Ser Leu 
            260                 265                 270         


Ala Asn Val Ser Tyr Gly Ser Ile Val Thr Tyr Thr Cys Asp Pro Asp 
        275                 280                 285             


Pro Glu Glu Gly Val Asn Phe Ile Leu Ile Gly Glu Ser Thr Leu Arg 
    290                 295                 300                 


Cys Thr Val Asp Ser Gln Lys Thr Gly Thr Trp Ser Gly Pro Ala Pro 
305                 310                 315                 320 


Arg Cys Glu Leu Ser Thr Ser Ala Val Gln Cys Pro His Pro Gln Ile 
                325                 330                 335     


Leu Arg Gly Arg Met Val Ser Gly Gln Lys Asp Arg Tyr Thr Tyr Asn 
            340                 345                 350         


Asp Thr Val Ile Phe Ala Cys Met Phe Gly Phe Thr Leu Lys Gly Ser 
        355                 360                 365             


Lys Gln Ile Arg Cys Asn Ala Gln Gly Thr Trp Glu Pro Ser Ala Pro 
    370                 375                 380                 


Val Cys Glu Lys Glu Cys Gln Ala Pro Pro Asn Ile Leu Asn Gly Gln 
385                 390                 395                 400 


Lys Glu Asp Arg His Met Val Arg Phe Asp Pro Gly Thr Ser Ile Lys 
                405                 410                 415     


Tyr Ser Cys Asn Pro Gly Tyr Val Leu Val Gly Glu Glu Ser Ile Gln 
            420                 425                 430         


Cys Thr Ser Glu Gly Val Trp Thr Pro Pro Val Pro Gln Cys Lys Val 
        435                 440                 445             


Ala Ala Cys Glu Ala Thr Gly Arg Gln Leu Leu Thr Lys Pro Gln His 
    450                 455                 460                 


Gln Phe Val Arg Pro Asp Val Asn Ser Ser Cys Gly Glu Gly Tyr Lys 
465                 470                 475                 480 


Leu Ser Gly Ser Val Tyr Gln Glu Cys Gln Gly Thr Ile Pro Trp Phe 
                485                 490                 495     


Met Glu Ile Arg Leu Cys Lys Glu Ile Thr Cys Pro Pro Pro Pro Val 
            500                 505                 510         


Ile Tyr Asn Gly Ala His Thr Gly Ser Ser Leu Glu Asp Phe Pro Tyr 
        515                 520                 525             


Gly Thr Thr Val Thr Tyr Thr Cys Asn Pro Gly Pro Glu Arg Gly Val 
    530                 535                 540                 


Glu Phe Ser Leu Ile Gly Glu Ser Thr Ile Arg Cys Thr Ser Asn Asp 
545                 550                 555                 560 


Gln Glu Arg Gly Thr Trp Ser Gly Pro Ala Pro Leu Cys Lys Leu Ser 
                565                 570                 575     


Leu Leu Ala Val Gln Cys Ser His Val His Ile Ala Asn Gly Tyr Lys 
            580                 585                 590         


Ile Ser Gly Lys Glu Ala Pro Tyr Phe Tyr Asn Asp Thr Val Thr Phe 
        595                 600                 605             


Lys Cys Tyr Ser Gly Phe Thr Leu Lys Gly Ser Ser Gln Ile Arg Cys 
    610                 615                 620                 


Lys Ala Asp Asn Thr Trp Asp Pro Glu Ile Pro Val Cys Glu Lys Gly 
625                 630                 635                 640 


Cys Gln Ser Pro Pro Gly Leu His His Gly Arg His Thr Gly Gly Asn 
                645                 650                 655     


Thr Val Phe Phe Val Ser Gly Met Thr Val Asp Tyr Thr Cys Asp Pro 
            660                 665                 670         


Gly Tyr Leu Leu Val Gly Asn Lys Ser Ile His Cys Met Pro Ser Gly 
        675                 680                 685             


Asn Trp Ser Pro Ser Ala Pro Arg Cys Glu Glu Thr Cys Gln His Val 
    690                 695                 700                 


Arg Gln Ser Leu Gln Glu Leu Pro Ala Gly Ser Arg Val Glu Leu Val 
705                 710                 715                 720 


Asn Thr Ser Cys Gln Asp Gly Tyr Gln Leu Thr Gly His Ala Tyr Gln 
                725                 730                 735     


Met Cys Gln Asp Ala Glu Asn Gly Ile Trp Phe Lys Lys Ile Pro Leu 
            740                 745                 750         


Cys Lys Val Ile His Cys His Pro Pro Pro Val Ile Val Asn Gly Lys 
        755                 760                 765             


His Thr Gly Met Met Ala Glu Asn Phe Leu Tyr Gly Asn Glu Val Ser 
    770                 775                 780                 


Tyr Glu Cys Asp Gln Gly Phe Tyr Leu Leu Gly Glu Lys Lys Leu Gln 
785                 790                 795                 800 


Cys Arg Ser Asp Ser Lys Gly His Gly Ser Trp Ser Gly Pro Ser Pro 
                805                 810                 815     


Gln Cys Leu Arg Ser Pro Pro Val Thr Arg Cys Pro Asn Pro Glu Val 
            820                 825                 830         


Lys His Gly Tyr Lys Leu Asn Lys Thr His Ser Ala Tyr Ser His Asn 
        835                 840                 845             


Asp Ile Val Tyr Val Asp Cys Asn Pro Gly Phe Ile Met Asn Gly Ser 
    850                 855                 860                 


Arg Val Ile Arg Cys His Thr Asp Asn Thr Trp Val Pro Gly Val Pro 
865                 870                 875                 880 


Thr Cys Ile Lys Lys Ala Phe Ile Gly Cys Pro Pro Pro Pro Lys Thr 
                885                 890                 895     


Pro Asn Gly Asn His Thr Gly Gly Asn Ile Ala Arg Phe Ser Pro Gly 
            900                 905                 910         


Met Ser Ile Leu Tyr Ser Cys Asp Gln Gly Tyr Leu Leu Val Gly Glu 
        915                 920                 925             


Ala Leu Leu Leu Cys Thr His Glu Gly Thr Trp Ser Gln Pro Ala Pro 
    930                 935                 940                 


His Cys Lys Glu Val Asn Cys Ser Ser Pro Ala Asp Met Asp Gly Ile 
945                 950                 955                 960 


Gln Lys Gly Leu Glu Pro Arg Lys Met Tyr Gln Tyr Gly Ala Val Val 
                965                 970                 975     


Thr Leu Glu Cys Glu Asp Gly Tyr Met Leu Glu Gly Ser Pro Gln Ser 
            980                 985                 990         


Gln Cys Gln Ser Asp His Gln Trp  Asn Pro Pro Leu Ala  Val Cys Arg 
        995                 1000                 1005             


Ser Arg  
    1010 


<210>  2132
<211>  410
<212>  PRT
<213>  Homo Sapiens

<400>  2132

Glu Ile Cys Glu Val Ser Glu Glu Asn Tyr Ile Arg Leu Lys Pro Leu 
1               5                   10                  15      


Leu Asn Thr Met Ile Gln Ser Asn Tyr Asn Arg Gly Thr Ser Ala Val 
            20                  25                  30          


Asn Val Val Leu Ser Leu Lys Leu Val Gly Ile Gln Ile Gln Thr Leu 
        35                  40                  45              


Met Gln Lys Met Ile Gln Gln Ile Lys Tyr Asn Val Lys Ser Arg Leu 
    50                  55                  60                  


Ser Asp Val Ser Ser Gly Glu Leu Ala Leu Ile Ile Leu Ala Leu Gly 
65                  70                  75                  80  


Val Cys Arg Asn Ala Glu Glu Asn Leu Ile Tyr Asp Tyr His Leu Ile 
                85                  90                  95      


Asp Lys Leu Glu Asn Lys Phe Gln Ala Glu Ile Glu Asn Met Glu Ala 
            100                 105                 110         


His Asn Gly Thr Pro Leu Thr Asn Tyr Tyr Gln Leu Ser Leu Asp Val 
        115                 120                 125             


Leu Ala Leu Cys Leu Phe Asn Gly Asn Tyr Ser Thr Ala Glu Val Val 
    130                 135                 140                 


Asn His Phe Thr Pro Glu Asn Lys Asn Tyr Tyr Phe Gly Ser Gln Phe 
145                 150                 155                 160 


Ser Val Asp Thr Gly Ala Met Ala Val Leu Ala Leu Thr Cys Val Lys 
                165                 170                 175     


Lys Ser Leu Ile Asn Gly Gln Ile Lys Ala Asp Glu Gly Ser Leu Lys 
            180                 185                 190         


Asn Ile Ser Ile Tyr Thr Lys Ser Leu Val Glu Lys Ile Leu Ser Glu 
        195                 200                 205             


Lys Lys Glu Asn Gly Leu Ile Gly Asn Thr Phe Ser Thr Gly Glu Ala 
    210                 215                 220                 


Met Gln Ala Leu Phe Val Ser Ser Asp Tyr Tyr Asn Glu Asn Asp Trp 
225                 230                 235                 240 


Asn Cys Gln Gln Thr Leu Asn Thr Val Leu Thr Glu Ile Ser Gln Gly 
                245                 250                 255     


Ala Phe Ser Asn Pro Asn Ala Ala Ala Gln Val Leu Pro Ala Leu Met 
            260                 265                 270         


Gly Lys Thr Phe Leu Asp Ile Asn Lys Asp Ser Ser Cys Val Ser Ala 
        275                 280                 285             


Ser Gly Asn Phe Asn Ile Ser Ala Asp Glu Pro Ile Thr Val Thr Pro 
    290                 295                 300                 


Pro Asp Ser Gln Ser Tyr Ile Ser Val Asn Tyr Ser Val Arg Ile Asn 
305                 310                 315                 320 


Glu Thr Tyr Phe Thr Asn Val Thr Val Leu Asn Gly Ser Val Phe Leu 
                325                 330                 335     


Ser Val Met Glu Lys Ala Gln Lys Met Asn Asp Thr Ile Phe Gly Phe 
            340                 345                 350         


Thr Met Glu Glu Arg Ser Trp Gly Pro Tyr Ile Thr Cys Ile Gln Gly 
        355                 360                 365             


Leu Cys Ala Asn Asn Asn Asp Arg Thr Tyr Trp Glu Leu Leu Ser Gly 
    370                 375                 380                 


Gly Glu Pro Leu Ser Gln Gly Ala Gly Ser Tyr Val Val Arg Asn Gly 
385                 390                 395                 400 


Glu Asn Leu Glu Val Arg Trp Ser Lys Tyr 
                405                 410 


<210>  2133
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  2133

Glu Met Cys Glu Ile Pro Glu Met Asp Ser His Leu Val Glu Lys Leu 
1               5                   10                  15      


Gly Gln His Leu Leu Pro Trp Met Asp Arg Leu Ser Leu Glu His Leu 
            20                  25                  30          


Asn Pro Ser Ile Tyr Val Gly Leu Arg Leu Ser Ser Leu Gln Ala Gly 
        35                  40                  45              


Thr Lys Glu Asp Leu Tyr Leu His Ser Leu Lys Leu Gly Tyr Gln Gln 
    50                  55                  60                  


Cys Leu Leu Gly Ser Ala Phe Ser Glu Asp Asp Gly Asp Cys Gln Gly 
65                  70                  75                  80  


Lys Pro Ser Met Gly Gln Leu Ala Leu Tyr Leu Leu Ala Leu Arg Ala 
                85                  90                  95      


Asn Cys Glu Phe Val Arg Gly His Lys Gly Asp Arg Leu Val Ser Gln 
            100                 105                 110         


Leu Lys Trp Phe Leu Glu Asp Glu Lys Arg Ala Ile Gly His Asp His 
        115                 120                 125             


Lys Gly His Pro His Thr Ser Tyr Tyr Gln Tyr Gly Leu Gly Ile Leu 
    130                 135                 140                 


Ala Leu Cys Leu His Gln Lys Arg Val His Asp Ser Val Val Asp Lys 
145                 150                 155                 160 


Leu Leu Tyr Ala Val Glu Pro Phe His Gln Gly His His Ser Val Asp 
                165                 170                 175     


Thr Ala Ala Met Ala Gly Leu Ala Phe Thr Cys Leu Lys Arg Ser Asn 
            180                 185                 190         


Phe Asn Pro Gly Arg Arg Gln Arg Ile Thr Met Ala Ile Arg Thr Val 
        195                 200                 205             


Gln Glu Glu Ile Leu Lys Ala Gln Thr Pro Glu Gly His Phe Gly Asn 
    210                 215                 220                 


Val Tyr Ser Thr Pro Leu Ala Leu Gln Phe Leu Met Thr Ser Pro Met 
225                 230                 235                 240 


Arg Gly Ala Glu Leu Gly Thr Ala Cys Leu Lys Ala Arg Val Ala Leu 
                245                 250                 255     


Leu Ala Ser Leu Gln Asp Gly Ala Phe Gln Asn Ala Leu Met Ile Ser 
            260                 265                 270         


Gln Leu Leu Pro Val Leu Asn His Lys Thr Tyr Ile Asp Leu Ile Phe 
        275                 280                 285             


Pro Asp Cys Leu Ala Pro Arg Val Met Leu Glu Pro Ala Ala Glu Thr 
    290                 295                 300                 


Ile Pro Gln Thr Gln Glu Ile Ile Ser Val Thr Leu Gln Val Leu Ser 
305                 310                 315                 320 


Leu Leu Pro Pro Tyr Arg Gln Ser Ile Ser Val Leu Ala Gly Ser Thr 
                325                 330                 335     


Val Glu Asp Val Leu Lys Lys Ala His Glu Leu Gly Gly Phe Thr Tyr 
            340                 345                 350         


Glu Thr Gln Ala Ser Leu Ser Gly Pro Tyr Leu Thr Ser Val Met Gly 
        355                 360                 365             


Lys Ala Ala Gly Glu Arg Glu Phe Trp Gln Leu Leu Arg Asp Pro Asn 
    370                 375                 380                 


Thr Pro Leu Leu Gln Gly Ile Ala Asp Tyr Arg Pro Lys Asp Gly Glu 
385                 390                 395                 400 


Thr Ile Glu Leu Arg Leu Val Ser Trp 
                405                 


<210>  2134
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  2134

Ile Val Gly Gly Trp Glu Cys Glu Lys His Ser Gln Pro Trp Gln Val 
1               5                   10                  15      


Ala Val Tyr Ser His Gly Trp Ala His Cys Gly Gly Val Leu Val His 
            20                  25                  30          


Pro Gln Trp Val Leu Thr Ala Ala His Cys Leu Lys Lys Asn Ser Gln 
        35                  40                  45              


Val Trp Leu Gly Arg His Asn Leu Phe Glu Pro Glu Asp Thr Gly Gln 
    50                  55                  60                  


Arg Val Pro Val Ser His Ser Phe Pro His Pro Leu Tyr Asn Met Ser 
65                  70                  75                  80  


Leu Leu Lys His Gln Ser Leu Arg Pro Asp Glu Asp Ser Ser His Asp 
                85                  90                  95      


Leu Met Leu Leu Arg Leu Ser Glu Pro Ala Lys Ile Thr Asp Val Val 
            100                 105                 110         


Lys Val Leu Gly Leu Pro Thr Gln Glu Pro Ala Leu Gly Thr Thr Cys 
        115                 120                 125             


Tyr Ala Ser Gly Trp Gly Ser Ile Glu Pro Glu Glu Phe Leu Arg Pro 
    130                 135                 140                 


Arg Ser Leu Gln Cys Val Ser Leu His Leu Leu Ser Asn Asp Met Cys 
145                 150                 155                 160 


Ala Arg Ala Tyr Ser Glu Lys Val Thr Glu Phe Met Leu Cys Ala Gly 
                165                 170                 175     


Leu Trp Thr Gly Gly Lys Asp Thr Cys Gly Gly Asp Ser Gly Gly Pro 
            180                 185                 190         


Leu Val Cys Asn Gly Val Leu Gln Gly Ile Thr Ser Trp Gly Pro Glu 
        195                 200                 205             


Pro Cys Ala Leu Pro Glu Lys Pro Ala Val Tyr Thr Lys Val Val His 
    210                 215                 220                 


Tyr Arg Lys Trp Ile Lys Asp Thr Ile Ala Ala Asn Pro 
225                 230                 235         


<210>  2135
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  2135

Ile Val Gly Gly Arg Lys Ala Arg Pro Arg Gln Phe Pro Phe Leu Ala 
1               5                   10                  15      


Ser Ile Gln Asn Gln Gly Arg His Phe Cys Gly Gly Ala Leu Ile His 
            20                  25                  30          


Ala Arg Phe Val Met Thr Ala Ala Ser Cys Phe Gln Ser Gln Asn Pro 
        35                  40                  45              


Gly Val Ser Thr Val Val Leu Gly Ala Tyr Asp Leu Arg Arg Arg Glu 
    50                  55                  60                  


Arg Gln Ser Arg Gln Thr Phe Ser Ile Ser Ser Met Ser Glu Asn Gly 
65                  70                  75                  80  


Tyr Asp Pro Gln Gln Asn Leu Asn Asp Leu Met Leu Leu Gln Leu Asp 
                85                  90                  95      


Arg Glu Ala Asn Leu Thr Ser Ser Val Thr Ile Leu Pro Leu Pro Leu 
            100                 105                 110         


Gln Asn Ala Thr Val Glu Ala Gly Thr Arg Cys Gln Val Ala Gly Trp 
        115                 120                 125             


Gly Ser Gln Arg Ser Gly Gly Arg Leu Ser Arg Phe Pro Arg Phe Val 
    130                 135                 140                 


Asn Val Thr Val Thr Pro Glu Asp Gln Cys Arg Pro Asn Asn Val Cys 
145                 150                 155                 160 


Thr Gly Val Leu Thr Arg Arg Gly Gly Ile Cys Asn Gly Asp Gly Gly 
                165                 170                 175     


Thr Pro Leu Val Cys Glu Gly Leu Ala His Gly Val Ala Ser Phe Ser 
            180                 185                 190         


Leu Gly Pro Cys Gly Arg Gly Pro Asp Phe Phe Thr Arg Val Ala Leu 
        195                 200                 205             


Phe Arg Asp Trp Ile Asp Gly Val Leu Asn Asn Pro Gly Pro 
    210                 215                 220         


<210>  2136
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  2136

Ile Val Gly Gly Gln Glu Ala Pro Arg Ser Lys Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Arg Val Arg Asp Arg Tyr Trp Met His Phe Cys Gly Gly Ser 
            20                  25                  30          


Leu Ile His Pro Gln Trp Val Leu Thr Ala Ala His Cys Leu Gly Pro 
        35                  40                  45              


Asp Val Lys Asp Leu Ala Thr Leu Arg Val Gln Leu Arg Glu Gln His 
    50                  55                  60                  


Leu Tyr Tyr Gln Asp Gln Leu Leu Pro Val Ser Arg Ile Ile Val His 
65                  70                  75                  80  


Pro Gln Phe Tyr Ile Ile Gln Thr Gly Ala Asp Ile Ala Leu Leu Glu 
                85                  90                  95      


Leu Glu Glu Pro Val Asn Ile Ser Ser Arg Val His Thr Val Met Leu 
            100                 105                 110         


Pro Pro Ala Ser Glu Thr Phe Pro Pro Gly Met Pro Cys Trp Val Thr 
        115                 120                 125             


Gly Trp Gly Asp Val Asp Asn Asp Glu Pro Leu Pro Pro Pro Phe Pro 
    130                 135                 140                 


Leu Lys Gln Val Lys Val Pro Ile Met Glu Asn His Ile Cys Asp Ala 
145                 150                 155                 160 


Lys Tyr His Leu Gly Ala Tyr Thr Gly Asp Asp Val Arg Ile Ile Arg 
                165                 170                 175     


Asp Asp Met Leu Cys Ala Gly Asn Thr Arg Arg Asp Ser Cys Gln Gly 
            180                 185                 190         


Asp Ser Gly Gly Pro Leu Val Cys Lys Val Asn Gly Thr Trp Leu Gln 
        195                 200                 205             


Ala Gly Val Val Ser Trp Asp Glu Gly Cys Ala Gln Pro Asn Arg Pro 
    210                 215                 220                 


Gly Ile Tyr Thr Arg Val Thr Tyr Tyr Leu Asp Trp Ile His His Tyr 
225                 230                 235                 240 


Val Pro Lys Lys Pro 
                245 


<210>  2137
<211>  144
<212>  PRT
<213>  Homo Sapiens

<400>  2137

Ile Leu Leu Ser Ala Ser Lys Ser Ile Arg Asn Leu Asp Asp Asp Met 
1               5                   10                  15      


Val Phe Asn Thr Phe Arg Leu Gly Lys Gly Phe Gln Lys Glu Asp Thr 
            20                  25                  30          


Ala Glu Lys Ser Val Ile Ala Pro Ser Leu Glu Gln Tyr Lys Asn Asp 
        35                  40                  45              


Glu Ser Ser Phe Met Asn Glu Glu Glu Asn Lys Val Ser Lys Asn Thr 
    50                  55                  60                  


Gly Ser Lys His Asn Phe Leu Asn His Gly Leu Pro Leu Asn Leu Ala 
65                  70                  75                  80  


Ile Lys Pro Tyr Leu Ala Leu Lys Gly Ser Val Ala Phe Pro Ala Glu 
                85                  90                  95      


Asn Gly Val Gln Asn Thr Glu Ser Thr Gln Glu Lys Arg Glu Ile Gly 
            100                 105                 110         


Asp Glu Glu Asn Ser Ala Lys Phe Pro Ile Gly Arg Arg Asp Phe Asp 
        115                 120                 125             


Met Leu Arg Cys Met Leu Gly Arg Val Tyr Arg Pro Cys Trp Gln Val 
    130                 135                 140                 


<210>  2138
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  2138

Gln Pro Glu Ala Ala Gln Gln Glu Ala Val Thr Ala Ala Glu His Pro 
1               5                   10                  15      


Gly Leu Asp Asp Phe Leu Arg Gln Val Glu Arg Leu Leu Phe Leu Arg 
            20                  25                  30          


Glu Asn Ile Gln Arg Leu Gln Gly Asp Gln Gly Glu His Ser Ala Ser 
        35                  40                  45              


Gln Ile Phe Gln Ser Asp Trp Leu Ser Lys Arg Gln His Pro Gly Lys 
    50                  55                  60                  


Arg Glu Glu Glu Glu Glu Glu Gly Val Glu Glu Glu Glu Glu Glu Glu 
65                  70                  75                  80  


Gly Gly Ala Val Gly Pro His Lys Arg Gln His Pro Gly Arg Arg Glu 
                85                  90                  95      


Asp Glu Ala Ser Trp Ser Val Asp Val Thr Gln His Lys Arg Gln His 
            100                 105                 110         


Pro Gly Arg Arg Ser Pro Trp Leu Ala Tyr Ala Val Pro Lys Arg Gln 
        115                 120                 125             


His Pro Gly Arg Arg Leu Ala Asp Pro Lys Ala Gln Arg Ser Trp Glu 
    130                 135                 140                 


Glu Glu Glu Glu Glu Glu Glu Arg Glu Glu Asp Leu Met Pro Glu Lys 
145                 150                 155                 160 


Arg Gln His Pro Gly Lys Arg Ala Leu Gly Gly Pro Cys Gly Pro Gln 
                165                 170                 175     


Gly Ala Tyr Gly Gln Ala Gly Leu Leu Leu Gly Leu Leu Asp Asp Leu 
            180                 185                 190         


Ser Arg Ser Gln Gly Ala Glu Glu Lys Arg Gln His Pro Gly Arg Arg 
        195                 200                 205             


Ala Ala Trp Val Arg Glu Pro Leu Glu Glu 
    210                 215             


<210>  2139
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  2139

Ile Ile Gly Gly His Glu Ala Lys Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Phe Val Gln Phe Leu Gln Glu Lys Ser Arg Lys Arg Cys Gly Gly Ile 
            20                  25                  30          


Leu Val Arg Lys Asp Phe Val Leu Thr Ala Ala His Cys Gln Gly Ser 
        35                  40                  45              


Ser Ile Asn Val Thr Leu Gly Ala His Asn Ile Lys Glu Gln Glu Arg 
    50                  55                  60                  


Thr Gln Gln Phe Ile Pro Val Lys Arg Pro Ile Pro His Pro Ala Tyr 
65                  70                  75                  80  


Asn Pro Lys Asn Phe Ser Asn Asp Ile Met Leu Leu Gln Leu Glu Arg 
                85                  90                  95      


Lys Ala Lys Trp Thr Thr Ala Val Arg Pro Leu Arg Leu Pro Ser Ser 
            100                 105                 110         


Lys Ala Gln Val Lys Pro Gly Gln Leu Cys Ser Val Ala Gly Trp Gly 
        115                 120                 125             


Tyr Val Ser Met Ser Thr Leu Ala Thr Thr Leu Gln Glu Val Leu Leu 
    130                 135                 140                 


Thr Val Gln Lys Asp Cys Gln Cys Glu Arg Leu Phe His Gly Asn Tyr 
145                 150                 155                 160 


Ser Arg Ala Thr Glu Ile Cys Val Gly Asp Pro Lys Lys Thr Gln Thr 
                165                 170                 175     


Gly Phe Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Lys Asp Val Ala 
            180                 185                 190         


Gln Gly Ile Leu Ser Tyr Gly Asn Lys Lys Gly Thr Pro Pro Gly Val 
        195                 200                 205             


Tyr Ile Lys Val Ser His Phe Leu Pro Trp Ile Lys Arg Thr Met Lys 
    210                 215                 220                 


Arg Leu 
225     


<210>  2140
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2140

Ser Asp Glu His Cys Pro Glu Leu Pro Pro Val Asp Asn Ser Ile Phe 
1               5                   10                  15      


Val Ala Lys Glu Val Glu Gly Gln Ile Leu Gly Thr Tyr Val Cys Ile 
            20                  25                  30          


Lys Gly Tyr His Leu Val Gly Lys Lys Thr Leu Phe Cys Asn Ala Ser 
        35                  40                  45              


Lys Glu Trp Asp Asn Thr Thr Thr Glu Cys Arg Leu Gly His Cys Pro 
    50                  55                  60                  


Asp Pro Val Leu Val Asn Gly Glu Phe Ser Ser Ser Gly Pro Val Asn 
65                  70                  75                  80  


Val Ser Asp Lys Ile Thr Phe Met Cys Asn Asp His Tyr Ile Leu Lys 
                85                  90                  95      


Gly Ser Asn Arg Ser Gln Cys Leu Glu Asp His Thr Trp Ala Pro Pro 
            100                 105                 110         


Phe Pro Ile Cys Lys Ser Arg Asp Cys Asp Pro Pro Gly Asn Pro Val 
        115                 120                 125             


His Gly Tyr Phe Glu Gly Asn Asn Phe Thr Leu Gly Ser Thr Ile Ser 
    130                 135                 140                 


Tyr Tyr Cys Glu Asp Arg Tyr Tyr Leu Val Gly Val Gln Glu Gln Gln 
145                 150                 155                 160 


Cys Val Asp Gly Glu Trp Ser Ser Ala Leu Pro Val Cys Lys Leu Ile 
                165                 170                 175     


Gln Glu Ala Pro Lys Pro Glu Cys Glu Lys Ala Leu Leu Ala Phe Gln 
            180                 185                 190         


Glu Ser Lys Asn Leu Cys Glu Ala Met Glu Asn Phe Met Gln Gln Leu 
        195                 200                 205             


Lys Glu Ser Gly Met Thr Met Glu Glu Leu Lys Tyr Ser Leu Glu Leu 
    210                 215                 220                 


Lys Lys Ala Glu Leu Lys Ala Lys Leu Leu 
225                 230                 


<210>  2141
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  2141

Ser Ser Pro Leu Pro Leu Val Val Asn Thr Trp Pro Phe Lys Asn Ala 
1               5                   10                  15      


Thr Glu Ala Ala Trp Arg Ala Leu Ala Ser Gly Gly Ser Ala Leu Asp 
            20                  25                  30          


Ala Val Glu Ser Gly Cys Ala Met Cys Glu Arg Glu Gln Cys Asp Gly 
        35                  40                  45              


Ser Val Gly Phe Gly Gly Ser Pro Asp Glu Leu Gly Glu Thr Thr Leu 
    50                  55                  60                  


Asp Ala Met Ile Met Asp Gly Thr Thr Met Asp Val Gly Ala Val Gly 
65                  70                  75                  80  


Asp Leu Arg Arg Ile Lys Asn Ala Ile Gly Val Ala Arg Lys Val Leu 
                85                  90                  95      


Glu His Thr Thr His Thr Leu Leu Val Gly Glu Ser Ala Thr Thr Phe 
            100                 105                 110         


Ala Gln Ser Met Gly Phe Ile Asn Glu Asp Leu Ser Thr Ser Ala Ser 
        115                 120                 125             


Gln Ala Leu His Ser Asp Trp Leu Ala Arg Asn Cys Gln Pro Asn Tyr 
    130                 135                 140                 


Trp Arg Asn Val Ile Pro Asp Pro Ser Lys Tyr Cys Gly Pro Tyr Lys 
145                 150                 155                 160 


Pro Pro Gly Ile Leu Lys Gln Asp Ile Pro Ile His Lys Glu Thr Glu 
                165                 170                 175     


Asp Asp Arg Gly His Asp Thr Ile Gly Met Val Val Ile His Lys Thr 
            180                 185                 190         


Gly His Ile Ala Ala Gly Thr Ser Thr Asn Gly Ile Lys Phe Lys Ile 
        195                 200                 205             


His Gly Arg Val Gly Asp Ser Pro Ile Pro Gly Ala Gly Ala Tyr Ala 
    210                 215                 220                 


Asp Asp Thr Ala Gly Ala Ala Ala Ala Thr Gly Asn Gly Asp Ile Leu 
225                 230                 235                 240 


Met Arg Phe Leu Pro Ser Tyr Gln Ala Val Glu Tyr Met Arg Arg Gly 
                245                 250                 255     


Glu Asp Pro Thr Ile Ala Cys Gln Lys Val Ile Ser Arg Ile Gln Lys 
            260                 265                 270         


His Phe Pro Glu Phe Phe Gly Ala Val Ile Cys Ala Asn Val Thr Gly 
        275                 280                 285             


Ser Tyr Gly Ala Ala Cys Asn Lys Leu Ser Thr Phe Thr Gln Phe Ser 
    290                 295                 300                 


Phe Met Val Tyr Asn Ser Glu Lys Asn Gln Pro Thr Glu Glu Lys Val 
305                 310                 315                 320 


Asp Cys Ile 
            


<210>  2142
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  2142

Gly Lys Lys Glu Lys Pro Glu Lys Lys Val Lys Lys Ser Asp Cys Gly 
1               5                   10                  15      


Glu Trp Gln Trp Ser Val Cys Val Pro Thr Ser Gly Asp Cys Gly Leu 
            20                  25                  30          


Gly Thr Arg Glu Gly Thr Arg Thr Gly Ala Glu Cys Lys Gln Thr Met 
        35                  40                  45              


Lys Thr Gln Arg Cys Lys Ile Pro Cys Asn Trp Lys Lys Gln Phe Gly 
    50                  55                  60                  


Ala Glu Cys Lys Tyr Gln Phe Gln Ala Trp Gly Glu Cys Asp Leu Asn 
65                  70                  75                  80  


Thr Ala Leu Lys Thr Arg Thr Gly Ser Leu Lys Arg Ala Leu His Asn 
                85                  90                  95      


Ala Glu Cys Gln Lys Thr Val Thr Ile Ser Lys Pro Cys Gly Lys Leu 
            100                 105                 110         


Thr Lys Pro Lys Pro Gln Ala Glu Ser Lys Lys Lys Lys Lys Glu Gly 
        115                 120                 125             


Lys Lys Gln Glu Lys Met Leu Asp 
    130                 135     


<210>  2143
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2143

Val Ala Lys Lys Lys Asp Lys Val Lys Lys Gly Gly Pro Gly Ser Glu 
1               5                   10                  15      


Cys Ala Glu Trp Ala Trp Gly Pro Cys Thr Pro Ser Ser Lys Asp Cys 
            20                  25                  30          


Gly Val Gly Phe Arg Glu Gly Thr Cys Gly Ala Gln Thr Gln Arg Ile 
        35                  40                  45              


Arg Cys Arg Val Pro Cys Asn Trp Lys Lys Glu Phe Gly Ala Asp Cys 
    50                  55                  60                  


Lys Tyr Lys Phe Glu Asn Trp Gly Ala Cys Asp Gly Gly Thr Gly Thr 
65                  70                  75                  80  


Lys Val Arg Gln Gly Thr Leu Lys Lys Ala Arg Tyr Asn Ala Gln Cys 
                85                  90                  95      


Gln Glu Thr Ile Arg Val Thr Lys Pro Cys Thr Pro Lys Thr Lys Ala 
            100                 105                 110         


Lys Ala Lys Ala Lys Lys Gly Lys Gly Lys Asp 
        115                 120             


<210>  2144
<211>  301
<212>  PRT
<213>  Homo Sapiens

<400>  2144

Phe Ser Met Lys Asn Leu His Arg Arg Val Lys Ile Glu Asp Ser Glu 
1               5                   10                  15      


Glu Asn Gly Val Phe Lys Tyr Arg Pro Arg Tyr Tyr Leu Tyr Lys His 
            20                  25                  30          


Ala Tyr Phe Tyr Pro His Leu Lys Arg Phe Pro Val Gln Gly Ser Ser 
        35                  40                  45              


Asp Ser Ser Glu Glu Asn Gly Asp Asp Ser Ser Glu Glu Glu Glu Glu 
    50                  55                  60                  


Glu Glu Glu Thr Ser Asn Glu Gly Glu Asn Asn Glu Glu Ser Asn Glu 
65                  70                  75                  80  


Asp Glu Asp Ser Glu Ala Glu Asn Thr Thr Leu Ser Ala Thr Thr Leu 
                85                  90                  95      


Gly Tyr Gly Glu Asp Ala Thr Pro Gly Thr Gly Tyr Thr Gly Leu Ala 
            100                 105                 110         


Ala Ile Gln Leu Pro Lys Lys Ala Gly Asp Ile Thr Asn Lys Ala Thr 
        115                 120                 125             


Lys Glu Lys Glu Ser Asp Glu Glu Glu Glu Glu Glu Glu Glu Gly Asn 
    130                 135                 140                 


Glu Asn Glu Glu Ser Glu Ala Glu Val Asp Glu Asn Glu Gln Gly Ile 
145                 150                 155                 160 


Asn Gly Thr Ser Thr Asn Ser Thr Glu Ala Glu Asn Gly Asn Gly Ser 
                165                 170                 175     


Ser Gly Gly Asp Asn Gly Glu Glu Gly Glu Glu Glu Ser Val Thr Gly 
            180                 185                 190         


Ala Asn Ala Glu Asp Thr Thr Glu Thr Gly Arg Gln Gly Lys Gly Thr 
        195                 200                 205             


Ser Lys Thr Thr Thr Ser Pro Asn Gly Gly Phe Glu Pro Thr Thr Pro 
    210                 215                 220                 


Pro Gln Val Tyr Arg Thr Thr Ser Pro Pro Phe Gly Lys Thr Thr Thr 
225                 230                 235                 240 


Val Glu Tyr Glu Gly Glu Tyr Glu Tyr Thr Gly Ala Asn Glu Tyr Asp 
                245                 250                 255     


Asn Gly Tyr Glu Ile Tyr Glu Ser Glu Asn Gly Glu Pro Arg Gly Asp 
            260                 265                 270         


Asn Tyr Arg Ala Tyr Glu Asp Glu Tyr Ser Tyr Phe Lys Gly Gln Gly 
        275                 280                 285             


Tyr Asp Gly Tyr Asp Gly Gln Asn Tyr Tyr His His Gln 
    290                 295                 300     


<210>  2145
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  2145

Arg His Trp Gly Trp Gly Leu Cys Leu Ile Gly Trp Asn Glu Phe Ile 
1               5                   10                  15      


Leu Gln Pro Ile His Asn Leu Leu Met Gly Asp Thr Lys Glu Gln Arg 
            20                  25                  30          


Ile Leu Asn His Val Leu Gln His Ala Glu Pro Gly Asn Ala Gln Ser 
        35                  40                  45              


Val Leu Glu Ala Ile Asp Thr Tyr Cys Glu Gln Lys Glu Trp Ala Met 
    50                  55                  60                  


Asn Val Gly Asp Lys Lys Gly Lys Ile Val Asp Ala Val Ile Gln Glu 
65                  70                  75                  80  


His Gln Pro Ser Val Leu Leu Glu Leu Gly Ala Tyr Cys Gly Tyr Ser 
                85                  90                  95      


Ala Val Arg Met Ala Arg Leu Leu Ser Pro Gly Ala Arg Leu Ile Thr 
            100                 105                 110         


Ile Glu Ile Asn Pro Asp Cys Ala Ala Ile Thr Gln Arg Met Val Asp 
        115                 120                 125             


Phe Ala Gly Val Lys Asp Lys Val Thr Leu Val Val Gly Ala Ser Gln 
    130                 135                 140                 


Asp Ile Ile Pro Gln Leu Lys Lys Lys Tyr Asp Val Asp Thr Leu Asp 
145                 150                 155                 160 


Met Val Phe Leu Asp His Trp Lys Asp Arg Tyr Leu Pro Asp Thr Leu 
                165                 170                 175     


Leu Leu Glu Glu Cys Gly Leu Leu Arg Lys Gly Thr Val Leu Leu Ala 
            180                 185                 190         


Asp Asn Val Ile Cys Pro Gly Ala Pro Asp Phe Leu Ala His Val Arg 
        195                 200                 205             


Gly Ser Ser Cys Phe Glu Cys Thr His Tyr Gln Ser Phe Leu Glu Tyr 
    210                 215                 220                 


Arg Glu Val Val Asp Gly Leu Glu Lys Ala Ile Tyr Lys Gly Pro Gly 
225                 230                 235                 240 


Ser Glu Ala Gly Pro 
                245 


<210>  2146
<211>  465
<212>  PRT
<213>  Homo Sapiens

<400>  2146

His Ala Gly Lys Ile Leu Leu Ile Pro Val Asp Gly Ser His Trp Leu 
1               5                   10                  15      


Ser Met Leu Gly Ala Ile Gln Gln Leu Gln Gln Arg Gly His Glu Ile 
            20                  25                  30          


Val Val Leu Ala Pro Asp Ala Ser Leu Tyr Ile Arg Asp Gly Ala Phe 
        35                  40                  45              


Tyr Thr Leu Lys Thr Tyr Pro Val Pro Phe Gln Arg Glu Asp Val Lys 
    50                  55                  60                  


Glu Ser Phe Val Ser Leu Gly His Asn Val Phe Glu Asn Asp Ser Phe 
65                  70                  75                  80  


Leu Gln Arg Val Ile Lys Thr Tyr Lys Lys Ile Lys Lys Asp Ser Ala 
                85                  90                  95      


Met Leu Leu Ser Gly Cys Ser His Leu Leu His Asn Lys Glu Leu Met 
            100                 105                 110         


Ala Ser Leu Ala Glu Ser Ser Phe Asp Val Met Leu Thr Asp Pro Phe 
        115                 120                 125             


Leu Pro Cys Ser Pro Ile Val Ala Gln Tyr Leu Ser Leu Pro Thr Val 
    130                 135                 140                 


Phe Phe Leu His Ala Leu Pro Cys Ser Leu Glu Phe Glu Ala Thr Gln 
145                 150                 155                 160 


Cys Pro Asn Pro Phe Ser Tyr Val Pro Arg Pro Leu Ser Ser His Ser 
                165                 170                 175     


Asp His Met Thr Phe Leu Gln Arg Val Lys Asn Met Leu Ile Ala Phe 
            180                 185                 190         


Ser Gln Asn Phe Leu Cys Asp Val Val Tyr Ser Pro Tyr Ala Thr Leu 
        195                 200                 205             


Ala Ser Glu Phe Leu Gln Arg Glu Val Thr Val Gln Asp Leu Leu Ser 
    210                 215                 220                 


Ser Ala Ser Val Trp Leu Phe Arg Ser Asp Phe Val Lys Asp Tyr Pro 
225                 230                 235                 240 


Arg Pro Ile Met Pro Asn Met Val Phe Val Gly Gly Ile Asn Cys Leu 
                245                 250                 255     


His Gln Asn Pro Leu Ser Gln Glu Phe Glu Ala Tyr Ile Asn Ala Ser 
            260                 265                 270         


Gly Glu His Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu 
        275                 280                 285             


Ile Pro Glu Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile 
    290                 295                 300                 


Pro Gln Thr Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu 
305                 310                 315                 320 


Ala Asn Asn Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu 
                325                 330                 335     


Gly His Pro Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly 
            340                 345                 350         


Val Tyr Glu Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu 
        355                 360                 365             


Phe Gly Asp Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala 
    370                 375                 380                 


Gly Val Thr Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn 
385                 390                 395                 400 


Ala Leu Lys Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met 
                405                 410                 415     


Arg Leu Ser Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu 
            420                 425                 430         


Ala Val Phe Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His 
        435                 440                 445             


Leu Arg Pro Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu 
    450                 455                 460                 


Asp 
465 


<210>  2147
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  2147

Gly Lys Val Leu Val Val Pro Thr Asp Gly Ser Pro Trp Leu Ser Met 
1               5                   10                  15      


Arg Glu Ala Leu Arg Glu Leu His Ala Arg Gly His Gln Ala Val Val 
            20                  25                  30          


Leu Thr Pro Glu Val Asn Met His Ile Lys Glu Glu Lys Phe Phe Thr 
        35                  40                  45              


Leu Thr Ala Tyr Ala Val Pro Trp Thr Gln Lys Glu Phe Asp Arg Val 
    50                  55                  60                  


Thr Leu Gly Tyr Thr Gln Gly Phe Phe Glu Thr Glu His Leu Leu Lys 
65                  70                  75                  80  


Arg Tyr Ser Arg Ser Met Ala Ile Met Asn Asn Val Ser Leu Ala Leu 
                85                  90                  95      


His Arg Cys Cys Val Glu Leu Leu His Asn Glu Ala Leu Ile Arg His 
            100                 105                 110         


Leu Asn Ala Thr Ser Phe Asp Val Val Leu Thr Asp Pro Val Asn Leu 
        115                 120                 125             


Cys Gly Ala Val Leu Ala Lys Tyr Leu Ser Ile Pro Ala Val Phe Phe 
    130                 135                 140                 


Trp Arg Tyr Ile Pro Cys Asp Leu Asp Phe Lys Gly Thr Gln Cys Pro 
145                 150                 155                 160 


Asn Pro Ser Ser Tyr Ile Pro Lys Leu Leu Thr Thr Asn Ser Asp His 
                165                 170                 175     


Met Thr Phe Leu Gln Arg Val Lys Asn Met Leu Tyr Pro Leu Ala Leu 
            180                 185                 190         


Ser Tyr Ile Cys His Thr Phe Ser Ala Pro Tyr Ala Ser Leu Ala Ser 
        195                 200                 205             


Glu Leu Phe Gln Arg Glu Val Ser Val Val Asp Leu Val Ser Tyr Ala 
    210                 215                 220                 


Ser Val Trp Leu Phe Arg Gly Asp Phe Val Met Asp Tyr Pro Arg Pro 
225                 230                 235                 240 


Ile Met Pro Asn Met Val Phe Ile Gly Gly Ile Asn Cys Ala Asn Gly 
                245                 250                 255     


Lys Pro Leu Ser Gln Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu 
            260                 265                 270         


His Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro 
        275                 280                 285             


Glu Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile Pro Gln 
    290                 295                 300                 


Thr Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn 
305                 310                 315                 320 


Asn Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His 
                325                 330                 335     


Pro Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr 
            340                 345                 350         


Glu Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly 
        355                 360                 365             


Asp Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val 
    370                 375                 380                 


Thr Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu 
385                 390                 395                 400 


Lys Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu 
                405                 410                 415     


Ser Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val 
            420                 425                 430         


Phe Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg 
        435                 440                 445             


Pro Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460             


<210>  2148
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  2148

Asp Glu Ala Ile His Cys Pro Pro Cys Ser Glu Glu Lys Leu Ala Arg 
1               5                   10                  15      


Cys Arg Pro Pro Val Gly Cys Glu Glu Leu Val Arg Glu Pro Gly Cys 
            20                  25                  30          


Gly Cys Cys Ala Thr Cys Ala Leu Gly Leu Gly Met Pro Cys Gly Val 
        35                  40                  45              


Tyr Thr Pro Arg Cys Gly Ser Gly Leu Arg Cys Tyr Pro Pro Arg Gly 
    50                  55                  60                  


Val Glu Lys Pro Leu His Thr Leu Met His Gly Gln Gly Val Cys Met 
65                  70                  75                  80  


Glu Leu Ala Glu Ile Glu Ala Ile Gln Glu Ser Leu Gln Pro Ser Asp 
                85                  90                  95      


Lys Asp Glu Gly Asp His Pro Asn Asn Ser Phe Ser Pro Cys Ser Ala 
            100                 105                 110         


His Asp Arg Arg Cys Leu Gln Lys His Phe Ala Lys Ile Arg Asp Arg 
        115                 120                 125             


Ser Thr Ser Gly Gly Lys Met Lys Val Asn Gly Ala Pro Arg Glu Asp 
    130                 135                 140                 


Ala Arg Pro Val Pro Gln Gly Ser Cys Gln Ser Glu Leu His Arg Ala 
145                 150                 155                 160 


Leu Glu Arg Leu Ala Ala Ser Gln Ser Arg Thr His Glu Asp Leu Tyr 
                165                 170                 175     


Ile Ile Pro Ile Pro Asn Cys Asp Arg Asn Gly Asn Phe His Pro Lys 
            180                 185                 190         


Gln Cys His Pro Ala Leu Asp Gly Gln Arg Gly Lys Cys Trp Cys Val 
        195                 200                 205             


Asp Arg Lys Thr Gly Val Lys Leu Pro Gly Gly Leu Glu Pro Lys Gly 
    210                 215                 220                 


Glu Leu Asp Cys His Gln Leu Ala Asp Ser Phe Arg Glu 
225                 230                 235         


<210>  2149
<211>  266
<212>  PRT
<213>  Homo Sapiens

<400>  2149

Ala Glu Ser His Trp Cys Tyr Glu Val Gln Ala Glu Ser Ser Asn Tyr 
1               5                   10                  15      


Pro Cys Leu Val Pro Val Lys Trp Gly Gly Asn Cys Gln Lys Asp Arg 
            20                  25                  30          


Gln Ser Pro Ile Asn Ile Val Thr Thr Lys Ala Lys Val Asp Lys Lys 
        35                  40                  45              


Leu Gly Arg Phe Phe Phe Ser Gly Tyr Asp Lys Lys Gln Thr Trp Thr 
    50                  55                  60                  


Val Gln Asn Asn Gly His Ser Val Met Met Leu Leu Glu Asn Lys Ala 
65                  70                  75                  80  


Ser Ile Ser Gly Gly Gly Leu Pro Ala Pro Tyr Gln Ala Lys Gln Leu 
                85                  90                  95      


His Leu His Trp Ser Asp Leu Pro Tyr Lys Gly Ser Glu His Ser Leu 
            100                 105                 110         


Asp Gly Glu His Phe Ala Met Glu Met His Ile Val His Glu Lys Glu 
        115                 120                 125             


Lys Gly Thr Ser Arg Asn Val Lys Glu Ala Gln Asp Pro Glu Asp Glu 
    130                 135                 140                 


Ile Ala Val Leu Ala Phe Leu Val Glu Ala Gly Thr Gln Val Asn Glu 
145                 150                 155                 160 


Gly Phe Gln Pro Leu Val Glu Ala Leu Ser Asn Ile Pro Lys Pro Glu 
                165                 170                 175     


Met Ser Thr Thr Met Ala Glu Ser Ser Leu Leu Asp Leu Leu Pro Lys 
            180                 185                 190         


Glu Glu Lys Leu Arg His Tyr Phe Arg Tyr Leu Gly Ser Leu Thr Thr 
        195                 200                 205             


Pro Thr Cys Asp Glu Lys Val Val Trp Thr Val Phe Arg Glu Pro Ile 
    210                 215                 220                 


Gln Leu His Arg Glu Gln Ile Leu Ala Phe Ser Gln Lys Leu Tyr Tyr 
225                 230                 235                 240 


Asp Lys Glu Gln Thr Val Ser Met Lys Asp Asn Val Arg Pro Leu Gln 
                245                 250                 255     


Gln Leu Gly Gln Arg Thr Val Ile Lys Ser 
            260                 265     


<210>  2150
<211>  367
<212>  PRT
<213>  Homo Sapiens

<400>  2150

Leu Thr Pro Gly Asn Pro Lys Trp Glu Arg Thr Asn Leu Thr Tyr Arg 
1               5                   10                  15      


Ile Arg Asn Tyr Thr Pro Gln Leu Ser Glu Ala Glu Val Glu Arg Ala 
            20                  25                  30          


Ile Lys Asp Ala Phe Glu Leu Trp Ser Val Ala Ser Pro Leu Ile Phe 
        35                  40                  45              


Thr Arg Ile Ser Gln Gly Glu Ala Asp Ile Asn Ile Ala Phe Tyr Gln 
    50                  55                  60                  


Arg Asp His Gly Asp Asn Ser Pro Phe Asp Gly Pro Asn Gly Ile Leu 
65                  70                  75                  80  


Ala His Ala Phe Gln Pro Gly Gln Gly Ile Gly Gly Asp Ala His Phe 
                85                  90                  95      


Asp Ala Glu Glu Thr Trp Thr Asn Thr Ser Ala Asn Tyr Asn Leu Phe 
            100                 105                 110         


Leu Val Ala Ala His Glu Phe Gly His Ser Leu Gly Leu Ala His Ser 
        115                 120                 125             


Ser Asp Pro Gly Ala Leu Met Tyr Pro Asn Tyr Ala Phe Arg Glu Thr 
    130                 135                 140                 


Ser Asn Tyr Ser Leu Pro Gln Asp Asp Ile Asp Gly Ile Gln Ala Ile 
145                 150                 155                 160 


Tyr Gly Leu Ser Ser Asn Pro Ile Gln Pro Thr Gly Pro Ser Thr Pro 
                165                 170                 175     


Lys Pro Cys Asp Pro Ser Leu Thr Phe Asp Ala Ile Thr Thr Leu Arg 
            180                 185                 190         


Gly Glu Ile Leu Phe Phe Lys Asp Arg Tyr Phe Trp Arg Arg His Pro 
        195                 200                 205             


Gln Leu Gln Arg Val Glu Met Asn Phe Ile Ser Leu Phe Trp Pro Ser 
    210                 215                 220                 


Leu Pro Thr Gly Ile Gln Ala Ala Tyr Glu Asp Phe Asp Arg Asp Leu 
225                 230                 235                 240 


Ile Phe Leu Phe Lys Gly Asn Gln Tyr Trp Ala Leu Ser Gly Tyr Asp 
                245                 250                 255     


Ile Leu Gln Gly Tyr Pro Lys Asp Ile Ser Asn Tyr Gly Phe Pro Ser 
            260                 265                 270         


Ser Val Gln Ala Ile Asp Ala Ala Val Phe Tyr Arg Ser Lys Thr Tyr 
        275                 280                 285             


Phe Phe Val Asn Asp Gln Phe Trp Arg Tyr Asp Asn Gln Arg Gln Phe 
    290                 295                 300                 


Met Glu Pro Gly Tyr Pro Lys Ser Ile Ser Gly Ala Phe Pro Gly Ile 
305                 310                 315                 320 


Glu Ser Lys Val Asp Ala Val Phe Gln Gln Glu His Phe Phe His Val 
                325                 330                 335     


Phe Ser Gly Pro Arg Tyr Tyr Ala Phe Asp Leu Ile Ala Gln Arg Val 
            340                 345                 350         


Thr Arg Val Ala Arg Gly Asn Lys Trp Leu Asn Cys Arg Tyr Gly 
        355                 360                 365         


<210>  2151
<211>  549
<212>  PRT
<213>  Homo Sapiens

<400>  2151

Gly His Pro Ser Ser Pro Pro Val Val Asp Thr Val His Gly Lys Val 
1               5                   10                  15      


Leu Gly Lys Phe Val Ser Leu Glu Gly Phe Ala Gln Pro Val Ala Ile 
            20                  25                  30          


Phe Leu Gly Ile Pro Phe Ala Lys Pro Pro Leu Gly Pro Leu Arg Phe 
        35                  40                  45              


Thr Pro Pro Gln Pro Ala Glu Pro Trp Ser Phe Val Lys Asn Ala Thr 
    50                  55                  60                  


Ser Tyr Pro Pro Met Cys Thr Gln Asp Pro Lys Ala Gly Gln Leu Leu 
65                  70                  75                  80  


Ser Glu Leu Phe Thr Asn Arg Lys Glu Asn Ile Pro Leu Lys Leu Ser 
                85                  90                  95      


Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Thr Pro Ala Asp Leu Thr Lys 
            100                 105                 110         


Lys Asn Arg Leu Pro Val Met Val Trp Ile His Gly Gly Gly Leu Met 
        115                 120                 125             


Val Gly Ala Ala Ser Thr Tyr Asp Gly Leu Ala Leu Ala Ala His Glu 
    130                 135                 140                 


Asn Val Val Val Val Thr Ile Gln Tyr Arg Leu Gly Ile Trp Gly Phe 
145                 150                 155                 160 


Phe Ser Thr Gly Asp Glu His Ser Arg Gly Asn Trp Gly His Leu Asp 
                165                 170                 175     


Gln Val Ala Ala Leu Arg Trp Val Gln Asp Asn Ile Ala Ser Phe Gly 
            180                 185                 190         


Gly Asn Pro Gly Ser Val Thr Ile Phe Gly Glu Ser Ala Gly Gly Glu 
        195                 200                 205             


Ser Val Ser Val Leu Val Leu Ser Pro Leu Ala Lys Asn Leu Phe His 
    210                 215                 220                 


Arg Ala Ile Ser Glu Ser Gly Val Ala Leu Thr Ser Val Leu Val Lys 
225                 230                 235                 240 


Lys Gly Asp Val Lys Pro Leu Ala Glu Gln Ile Ala Ile Thr Ala Gly 
                245                 250                 255     


Cys Lys Thr Thr Thr Ser Ala Val Met Val His Cys Leu Arg Gln Lys 
            260                 265                 270         


Thr Glu Glu Glu Leu Leu Glu Thr Thr Leu Lys Met Lys Phe Leu Ser 
        275                 280                 285             


Leu Asp Leu Gln Gly Asp Pro Arg Glu Ser Gln Pro Leu Leu Gly Thr 
    290                 295                 300                 


Val Ile Asp Gly Met Leu Leu Leu Lys Thr Pro Glu Glu Leu Gln Ala 
305                 310                 315                 320 


Glu Arg Asn Phe His Thr Val Pro Tyr Met Val Gly Ile Asn Lys Gln 
                325                 330                 335     


Glu Phe Gly Trp Leu Ile Pro Met Leu Met Ser Tyr Pro Leu Ser Glu 
            340                 345                 350         


Gly Gln Leu Asp Gln Lys Thr Ala Met Ser Leu Leu Trp Lys Ser Tyr 
        355                 360                 365             


Pro Leu Val Cys Ile Ala Lys Glu Leu Ile Pro Glu Ala Thr Glu Lys 
    370                 375                 380                 


Tyr Leu Gly Gly Thr Asp Asp Thr Val Lys Lys Lys Asp Leu Phe Leu 
385                 390                 395                 400 


Asp Leu Ile Ala Asp Val Met Phe Gly Val Pro Ser Val Ile Val Ala 
                405                 410                 415     


Arg Asn His Arg Asp Ala Gly Ala Pro Thr Tyr Met Tyr Glu Phe Gln 
            420                 425                 430         


Tyr Arg Pro Ser Phe Ser Ser Asp Met Lys Pro Lys Thr Val Ile Gly 
        435                 440                 445             


Asp His Gly Asp Glu Leu Phe Ser Val Phe Gly Ala Pro Phe Leu Lys 
    450                 455                 460                 


Glu Gly Ala Ser Glu Glu Glu Ile Arg Leu Ser Lys Met Val Met Lys 
465                 470                 475                 480 


Phe Trp Ala Asn Phe Ala Arg Asn Gly Asn Pro Asn Gly Glu Gly Leu 
                485                 490                 495     


Pro His Trp Pro Glu Tyr Asn Gln Lys Glu Gly Tyr Leu Gln Ile Gly 
            500                 505                 510         


Ala Asn Thr Gln Ala Ala Gln Lys Leu Lys Asp Lys Glu Val Ala Phe 
        515                 520                 525             


Trp Thr Asn Leu Phe Ala Lys Lys Ala Val Glu Lys Pro Pro Gln Thr 
    530                 535                 540                 


Glu His Ile Glu Leu 
545                 


<210>  2152
<211>  665
<212>  PRT
<213>  Homo Sapiens

<400>  2152

Asn Phe Gln Asn Cys Gly Pro Arg Pro Cys Glu Thr Ser Val Cys Leu 
1               5                   10                  15      


Asp Leu Arg Asp His Tyr Leu Ala Ser Gly Asn Thr Ser Val Ala Pro 
            20                  25                  30          


Cys Thr Asp Phe Phe Ser Phe Ala Cys Gly Arg Ala Lys Glu Thr Asn 
        35                  40                  45              


Asn Ser Phe Gln Glu Leu Ala Thr Lys Asn Lys Asn Arg Leu Arg Arg 
    50                  55                  60                  


Ile Leu Glu Val Gln Asn Ser Trp His Pro Gly Ser Gly Glu Glu Lys 
65                  70                  75                  80  


Ala Phe Gln Phe Tyr Asn Ser Cys Met Asp Thr Leu Ala Ile Glu Ala 
                85                  90                  95      


Ala Gly Thr Gly Pro Leu Arg Gln Val Ile Glu Glu Leu Gly Gly Trp 
            100                 105                 110         


Arg Ile Ser Gly Lys Trp Thr Ser Leu Asn Phe Asn Arg Thr Leu Arg 
        115                 120                 125             


Leu Leu Met Ser Gln Tyr Gly His Phe Pro Phe Phe Arg Ala Tyr Leu 
    130                 135                 140                 


Gly Pro His Pro Ala Ser Pro His Thr Pro Val Ile Gln Ile Asp Gln 
145                 150                 155                 160 


Pro Glu Phe Asp Val Pro Leu Lys Gln Asp Gln Glu Gln Lys Ile Tyr 
                165                 170                 175     


Ala Gln Ile Phe Arg Glu Tyr Leu Thr Tyr Leu Asn Gln Leu Gly Thr 
            180                 185                 190         


Leu Leu Gly Gly Asp Pro Ser Lys Val Gln Glu His Ser Ser Leu Ser 
        195                 200                 205             


Ile Ser Ile Thr Ser Arg Leu Phe Gln Phe Leu Arg Pro Leu Glu Gln 
    210                 215                 220                 


Arg Arg Ala Gln Gly Lys Leu Phe Gln Met Val Thr Ile Asp Gln Leu 
225                 230                 235                 240 


Lys Glu Met Ala Pro Ala Ile Asp Trp Leu Ser Cys Leu Gln Ala Thr 
                245                 250                 255     


Phe Thr Pro Met Ser Leu Ser Pro Ser Gln Ser Leu Val Val His Asp 
            260                 265                 270         


Val Glu Tyr Leu Lys Asn Met Ser Gln Leu Val Glu Glu Met Leu Leu 
        275                 280                 285             


Lys Gln Arg Asp Phe Leu Gln Ser His Met Ile Leu Gly Leu Val Val 
    290                 295                 300                 


Thr Leu Ser Pro Ala Leu Asp Ser Gln Phe Gln Glu Ala Arg Arg Lys 
305                 310                 315                 320 


Leu Ser Gln Lys Leu Arg Glu Leu Thr Glu Gln Pro Pro Met Pro Ala 
                325                 330                 335     


Arg Pro Arg Trp Met Lys Cys Val Glu Glu Thr Gly Thr Phe Phe Glu 
            340                 345                 350         


Pro Thr Leu Ala Ala Leu Phe Val Arg Glu Ala Phe Gly Pro Ser Thr 
        355                 360                 365             


Arg Ser Ala Ala Met Lys Leu Phe Thr Ala Ile Arg Asp Ala Leu Ile 
    370                 375                 380                 


Thr Arg Leu Arg Asn Leu Pro Trp Met Asn Glu Glu Thr Gln Asn Met 
385                 390                 395                 400 


Ala Gln Asp Lys Val Ala Gln Leu Gln Val Glu Met Gly Ala Ser Glu 
                405                 410                 415     


Trp Ala Leu Lys Pro Glu Leu Ala Arg Gln Glu Tyr Asn Asp Ile Gln 
            420                 425                 430         


Leu Gly Ser Ser Phe Leu Gln Ser Val Leu Ser Cys Val Arg Ser Leu 
        435                 440                 445             


Arg Ala Arg Ile Val Gln Ser Phe Leu Gln Pro His Pro Gln His Arg 
    450                 455                 460                 


Trp Lys Val Ser Pro Trp Asp Val Asn Ala Tyr Tyr Ser Val Ser Asp 
465                 470                 475                 480 


His Val Val Val Phe Pro Ala Gly Leu Leu Gln Pro Pro Phe Phe His 
                485                 490                 495     


Pro Gly Tyr Pro Arg Ala Val Asn Phe Gly Ala Ala Gly Ser Ile Met 
            500                 505                 510         


Ala His Glu Leu Leu His Ile Phe Tyr Gln Leu Leu Leu Pro Gly Gly 
        515                 520                 525             


Cys Leu Ala Cys Asp Asn His Ala Leu Gln Glu Ala His Leu Cys Leu 
    530                 535                 540                 


Lys Arg His Tyr Ala Ala Phe Pro Leu Pro Ser Arg Thr Ser Phe Asn 
545                 550                 555                 560 


Asp Ser Leu Thr Phe Leu Glu Asn Ala Ala Asp Val Gly Gly Leu Ala 
                565                 570                 575     


Ile Ala Leu Gln Ala Tyr Ser Lys Arg Leu Leu Arg His His Gly Glu 
            580                 585                 590         


Thr Val Leu Pro Ser Leu Asp Leu Ser Pro Gln Gln Ile Phe Phe Arg 
        595                 600                 605             


Ser Tyr Ala Gln Val Met Cys Arg Lys Pro Ser Pro Gln Asp Ser His 
    610                 615                 620                 


Asp Thr His Ser Pro Pro His Leu Arg Val His Gly Pro Leu Ser Ser 
625                 630                 635                 640 


Thr Pro Ala Phe Ala Arg Tyr Phe Arg Cys Ala Arg Gly Ala Leu Leu 
                645                 650                 655     


Asn Pro Ser Ser Arg Cys Gln Leu Trp 
            660                 665 


<210>  2153
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2153

Asp Glu Lys Lys Lys Gly Pro Lys Val Thr Val Lys Val Tyr Phe Asp 
1               5                   10                  15      


Leu Arg Ile Gly Asp Glu Asp Val Gly Arg Val Ile Phe Gly Leu Phe 
            20                  25                  30          


Gly Lys Thr Val Pro Lys Thr Val Asp Asn Phe Val Ala Leu Ala Thr 
        35                  40                  45              


Gly Glu Lys Gly Phe Gly Tyr Lys Asn Ser Lys Phe His Arg Val Ile 
    50                  55                  60                  


Lys Asp Phe Met Ile Gln Gly Gly Asp Phe Thr Arg Gly Asp Gly Thr 
65                  70                  75                  80  


Gly Gly Lys Ser Ile Tyr Gly Glu Arg Phe Pro Asp Glu Asn Phe Lys 
                85                  90                  95      


Leu Lys His Tyr Gly Pro Gly Trp Val Ser Met Ala Asn Ala Gly Lys 
            100                 105                 110         


Asp Thr Asn Gly Ser Gln Phe Phe Ile Thr Thr Val Lys Thr Ala Trp 
        115                 120                 125             


Leu Asp Gly Lys His Val Val Phe Gly Lys Val Leu Glu Gly Met Glu 
    130                 135                 140                 


Val Val Arg Lys Val Glu Ser Thr Lys Thr Asp Ser Arg Asp Lys Pro 
145                 150                 155                 160 


Leu Lys Asp Val Ile Ile Ala Asp Cys Gly Lys Ile Glu Val Glu Lys 
                165                 170                 175     


Pro Phe Ala Ile Ala Lys Glu 
            180             


<210>  2154
<211>  671
<212>  PRT
<213>  Homo Sapiens

<400>  2154

Gln Leu Arg Gly Asp Gly Leu Gly Phe Arg Asn Arg Asn Asn Ser Thr 
1               5                   10                  15      


Gly Val Ala Gly Leu Ser Glu Glu Ala Ser Ala Glu Leu Arg His His 
            20                  25                  30          


Leu His Ser Pro Arg Asp His Pro Asp Glu Asn Lys Asp Val Ser Thr 
        35                  40                  45              


Glu Asn Gly His His Phe Trp Ser His Pro Asp Arg Glu Lys Glu Asp 
    50                  55                  60                  


Glu Asp Val Ser Lys Glu Tyr Gly His Leu Leu Pro Gly His Arg Ser 
65                  70                  75                  80  


Gln Asp His Lys Val Gly Asp Glu Gly Val Ser Gly Glu Glu Val Phe 
                85                  90                  95      


Ala Glu His Gly Gly Gln Ala Arg Gly His Arg Gly His Gly Ser Glu 
            100                 105                 110         


Asp Thr Glu Asp Ser Ala Glu His Arg His His Leu Pro Ser His Arg 
        115                 120                 125             


Ser His Ser His Gln Asp Glu Asp Glu Asp Glu Val Val Ser Ser Glu 
    130                 135                 140                 


His His His His Ile Leu Arg His Gly His Arg Gly His Asp Gly Glu 
145                 150                 155                 160 


Asp Asp Glu Gly Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu 
                165                 170                 175     


Ala Ser Thr Glu Tyr Gly His Gln Ala His Arg His Arg Gly His Gly 
            180                 185                 190         


Ser Glu Glu Asp Glu Asp Val Ser Asp Gly His His His His Gly Pro 
        195                 200                 205             


Ser His Arg His Gln Gly His Glu Glu Asp Asp Asp Asp Asp Asp Asp 
    210                 215                 220                 


Asp Asp Asp Asp Asp Asp Asp Asp Asp Val Ser Ile Glu Tyr Arg His 
225                 230                 235                 240 


Gln Ala His Arg His Gln Gly His Gly Ile Glu Glu Asp Glu Asp Val 
                245                 250                 255     


Ser Asp Gly His His His Arg Asp Pro Ser His Arg His Arg Ser His 
            260                 265                 270         


Glu Glu Asp Asp Asn Asp Asp Asp Asp Val Ser Thr Glu Tyr Gly His 
        275                 280                 285             


Gln Ala His Arg His Gln Asp His Arg Lys Glu Glu Val Glu Ala Val 
    290                 295                 300                 


Ser Gly Glu His His His His Val Pro Asp His Arg His Gln Gly His 
305                 310                 315                 320 


Arg Asp Glu Glu Glu Asp Glu Asp Val Ser Thr Glu Arg Trp His Gln 
                325                 330                 335     


Gly Pro Gln His Val His His Gly Leu Val Asp Glu Glu Glu Glu Glu 
            340                 345                 350         


Glu Glu Ile Thr Val Gln Phe Gly His Tyr Val Ala Ser His Gln Pro 
        355                 360                 365             


Arg Gly His Lys Ser Asp Glu Glu Asp Phe Gln Asp Glu Tyr Lys Thr 
    370                 375                 380                 


Glu Val Pro His His His His His Arg Val Pro Arg Glu Glu Asp Glu 
385                 390                 395                 400 


Glu Val Ser Ala Glu Leu Gly His Gln Ala Pro Ser His Arg Gln Ser 
                405                 410                 415     


His Gln Asp Glu Glu Thr Gly His Gly Gln Arg Gly Ser Ile Lys Glu 
            420                 425                 430         


Met Ser His His Pro Pro Gly His Thr Val Val Lys Asp Arg Ser His 
        435                 440                 445             


Leu Arg Lys Asp Asp Ser Glu Glu Glu Lys Glu Lys Glu Glu Asp Pro 
    450                 455                 460                 


Gly Ser His Glu Glu Asp Asp Glu Ser Ser Glu Gln Gly Glu Lys Gly 
465                 470                 475                 480 


Thr His His Gly Ser Arg Asp Gln Glu Asp Glu Glu Asp Glu Glu Glu 
                485                 490                 495     


Gly His Gly Leu Ser Leu Asn Gln Glu Glu Glu Glu Glu Glu Asp Lys 
            500                 505                 510         


Glu Glu Glu Glu Glu Glu Glu Asp Glu Glu Arg Arg Glu Glu Arg Ala 
        515                 520                 525             


Glu Val Gly Ala Pro Leu Ser Pro Asp His Ser Glu Glu Glu Glu Glu 
    530                 535                 540                 


Glu Glu Glu Gly Leu Glu Glu Asp Glu Pro Arg Phe Thr Ile Ile Pro 
545                 550                 555                 560 


Asn Pro Leu Asp Arg Arg Glu Glu Ala Gly Gly Ala Ser Ser Glu Glu 
                565                 570                 575     


Glu Ser Gly Glu Asp Thr Gly Pro Gln Asp Ala Gln Glu Tyr Gly Asn 
            580                 585                 590         


Tyr Gln Pro Gly Ser Leu Cys Gly Tyr Cys Ser Phe Cys Asn Arg Cys 
        595                 600                 605             


Thr Glu Cys Glu Ser Cys His Cys Asp Glu Glu Asn Met Gly Glu His 
    610                 615                 620                 


Cys Asp Gln Cys Gln His Cys Gln Phe Cys Tyr Leu Cys Pro Leu Val 
625                 630                 635                 640 


Cys Glu Thr Val Cys Ala Pro Gly Ser Tyr Val Asp Tyr Phe Ser Ser 
                645                 650                 655     


Ser Leu Tyr Gln Ala Leu Ala Asp Met Leu Glu Thr Pro Glu Pro 
            660                 665                 670     


<210>  2155
<211>  222
<212>  PRT
<213>  Homo Sapiens

<400>  2155

Ala Arg Ser Ala Pro Lys Pro Met Ser Pro Ser Asp Phe Leu Asp Lys 
1               5                   10                  15      


Leu Met Gly Arg Thr Ser Gly Tyr Asp Ala Arg Ile Arg Pro Asn Phe 
            20                  25                  30          


Lys Gly Pro Pro Val Asn Val Ser Cys Asn Ile Phe Ile Asn Ser Phe 
        35                  40                  45              


Gly Ser Ile Ala Glu Thr Thr Met Asp Tyr Arg Val Asn Ile Phe Leu 
    50                  55                  60                  


Arg Gln Gln Trp Asn Asp Pro Arg Leu Ala Tyr Asn Glu Tyr Pro Asp 
65                  70                  75                  80  


Asp Ser Leu Asp Leu Asp Pro Ser Met Leu Asp Ser Ile Trp Lys Pro 
                85                  90                  95      


Asp Leu Phe Phe Ala Asn Glu Lys Gly Ala His Phe His Glu Ile Thr 
            100                 105                 110         


Thr Asp Asn Lys Leu Leu Arg Ile Ser Arg Asn Gly Asn Val Leu Tyr 
        115                 120                 125             


Ser Ile Arg Ile Thr Leu Thr Leu Ala Cys Pro Met Asp Leu Lys Asn 
    130                 135                 140                 


Phe Pro Met Asp Val Gln Thr Cys Ile Met Gln Leu Glu Ser Phe Gly 
145                 150                 155                 160 


Tyr Thr Met Asn Asp Leu Ile Phe Glu Trp Gln Glu Gln Gly Ala Val 
                165                 170                 175     


Gln Val Ala Asp Gly Leu Thr Leu Pro Gln Phe Ile Leu Lys Glu Glu 
            180                 185                 190         


Lys Asp Leu Arg Tyr Cys Thr Lys His Tyr Asn Thr Gly Lys Phe Thr 
        195                 200                 205             


Cys Ile Glu Ala Arg Phe His Leu Glu Arg Gln Met Gly Tyr 
    210                 215                 220         


<210>  2156
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  2156

Lys Asp His Asp Ser Arg Ser Gly Lys Gln Pro Ser Gln Thr Leu Ser 
1               5                   10                  15      


Pro Ser Asp Phe Leu Asp Lys Leu Met Gly Arg Thr Ser Gly Tyr Asp 
            20                  25                  30          


Ala Arg Ile Arg Pro Asn Phe Lys Gly Pro Pro Val Asn Val Thr Cys 
        35                  40                  45              


Asn Ile Phe Ile Asn Ser Phe Gly Ser Val Thr Glu Thr Thr Met Asp 
    50                  55                  60                  


Tyr Arg Val Asn Ile Phe Leu Arg Gln Gln Trp Asn Asp Ser Arg Leu 
65                  70                  75                  80  


Ala Tyr Ser Glu Tyr Pro Asp Asp Ser Leu Asp Leu Asp Pro Ser Met 
                85                  90                  95      


Leu Asp Ser Ile Trp Lys Pro Asp Leu Phe Phe Ala Asn Glu Lys Gly 
            100                 105                 110         


Ala Asn Phe His Asp Val Thr Thr Asp Asn Lys Leu Leu Arg Ile Ser 
        115                 120                 125             


Lys Asn Gly Lys Val Leu Tyr Ser Ile Arg Leu Thr Leu Thr Leu Ser 
    130                 135                 140                 


Cys Pro Met Asp Leu Lys Asn Phe Pro Met Asp Val Gln Thr Cys Thr 
145                 150                 155                 160 


Met Gln Leu Glu Ser Phe Gly Tyr Thr Met Asn Asp Leu Ile Phe Glu 
                165                 170                 175     


Trp Leu Ser Asp Gly Pro Val Gln Val Ala Glu Gly Leu Thr Leu Pro 
            180                 185                 190         


Gln Phe Ile Leu Lys Glu Glu Lys Glu Leu Gly Tyr Cys Thr Lys His 
        195                 200                 205             


Tyr Asn Thr Gly Lys Phe Thr Cys Ile Glu Val Lys Phe His Leu Glu 
    210                 215                 220                 


Arg Gln Met Gly Tyr 
225                 


<210>  2157
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  2157

Gln Asn Glu Thr Glu Pro Ile Val Leu Glu Gly Lys Cys Leu Val Val 
1               5                   10                  15      


Cys Asp Ser Asn Pro Thr Ser Asp Pro Thr Gly Thr Ala Leu Gly Ile 
            20                  25                  30          


Ser Val Arg Ser Gly Ser Ala Lys Val Ala Phe Ser Ala Ile Arg Ser 
        35                  40                  45              


Thr Asn His Glu Pro Ser Glu Met Ser Asn Arg Thr Met Ile Ile Tyr 
    50                  55                  60                  


Phe Asp Gln Val Leu Val Asn Ile Gly Asn Asn Phe Asp Ser Glu Arg 
65                  70                  75                  80  


Ser Thr Phe Ile Ala Pro Arg Lys Gly Ile Tyr Ser Phe Asn Phe His 
                85                  90                  95      


Val Val Lys Val Tyr Asn Arg Gln Thr Ile Gln Val Ser Leu Met Leu 
            100                 105                 110         


Asn Gly Trp Pro Val Ile Ser Ala Phe Ala Gly Asp Gln Asp Val Thr 
        115                 120                 125             


Arg Glu Ala Ala Ser Asn Gly Val Leu Ile Gln Met Glu Lys Gly Asp 
    130                 135                 140                 


Arg Ala Tyr Leu Lys Leu Glu Arg Gly Asn Leu Met Gly Gly Trp Lys 
145                 150                 155                 160 


Tyr Ser Thr Phe Ser Gly Phe Leu Val Phe Pro Leu 
                165                 170         


<210>  2158
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2158

Asp Leu Arg Val Asp Thr Lys Ser Arg Ala Ala Trp Ala Arg Leu Leu 
1               5                   10                  15      


Gln Glu His Pro Asn Ala Arg Lys Tyr Lys Gly Ala Asn Lys Lys Gly 
            20                  25                  30          


Leu Ser Lys Gly Cys Phe Gly Leu Lys Leu Asp Arg Ile Gly Ser Met 
        35                  40                  45              


Ser Gly Leu Gly Cys 
    50              


<210>  2159
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  2159

Ile Ile Gly Gly Thr Glu Cys Lys Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Tyr Leu Glu Ile Val Thr Ser Asn Gly Pro Ser Lys Phe Cys Gly Gly 
            20                  25                  30          


Phe Leu Ile Arg Arg Asn Phe Val Leu Thr Ala Ala His Cys Ala Gly 
        35                  40                  45              


Arg Ser Ile Thr Val Thr Leu Gly Ala His Asn Ile Thr Glu Glu Glu 
    50                  55                  60                  


Asp Thr Trp Gln Lys Leu Glu Val Ile Lys Gln Phe Arg His Pro Lys 
65                  70                  75                  80  


Tyr Asn Thr Ser Thr Leu His His Asp Ile Met Leu Leu Lys Leu Lys 
                85                  90                  95      


Glu Lys Ala Ser Leu Thr Leu Ala Val Gly Thr Leu Pro Phe Pro Ser 
            100                 105                 110         


Gln Phe Asn Phe Val Pro Pro Gly Arg Met Cys Arg Val Ala Gly Trp 
        115                 120                 125             


Gly Arg Thr Gly Val Leu Lys Pro Gly Ser Asp Thr Leu Gln Glu Val 
    130                 135                 140                 


Lys Leu Arg Leu Met Asp Pro Gln Ala Cys Ser His Phe Arg Asp Phe 
145                 150                 155                 160 


Asp His Asn Leu Gln Leu Cys Val Gly Asn Pro Arg Lys Thr Lys Ser 
                165                 170                 175     


Ala Phe Lys Gly Asp Ser Gly Gly Pro Leu Leu Cys Ala Gly Val Ala 
            180                 185                 190         


Gln Gly Ile Val Ser Tyr Gly Arg Ser Asp Ala Lys Pro Pro Ala Val 
        195                 200                 205             


Phe Thr Arg Ile Ser His Tyr Arg Pro Trp Ile Asn Gln Ile Leu Gln 
    210                 215                 220                 


Ala Asn 
225     


<210>  2160
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  2160

Phe Thr Leu Asn Leu Pro Trp Thr Asp Cys Gly His Thr Trp Asn Ser 
1               5                   10                  15      


Pro Asn Cys Thr Asp Pro Lys Leu Leu Asn Gly Ser Val Leu Gly Asn 
            20                  25                  30          


His Thr Lys Tyr Ser Lys Tyr Lys Phe Thr Pro Ala Ala Glu Phe Tyr 
        35                  40                  45              


Glu Arg Gly Val Leu His Leu His Glu Ser Ser Gly Ile His Asp Ile 
    50                  55                  60                  


Gly Leu Pro 
65          


<210>  2161
<211>  261
<212>  PRT
<213>  Homo Sapiens

<400>  2161

Thr Glu Ser Arg Met His Trp Pro Gly Arg Glu Val His Glu Met Ser 
1               5                   10                  15      


Lys Lys Gly Ser Arg Pro Gln Arg Gln Arg Arg Glu Val His Glu Asp 
            20                  25                  30          


Ala His Lys Gln Val Ser Pro Ile Leu Arg Arg Ser Pro Asp Ile Thr 
        35                  40                  45              


Lys Ser Pro Leu Thr Lys Ser Glu Gln Leu Leu Arg Ile Asp Asp His 
    50                  55                  60                  


Asp Phe Ser Met Arg Pro Gly Phe Gly Gly Pro Ala Ile Pro Val Gly 
65                  70                  75                  80  


Val Asp Val Gln Val Glu Ser Leu Asp Ser Ile Ser Glu Val Asp Met 
                85                  90                  95      


Asp Phe Thr Met Thr Leu Tyr Leu Arg His Tyr Trp Lys Asp Glu Arg 
            100                 105                 110         


Leu Ser Phe Pro Ser Thr Asn Asn Leu Ser Met Thr Phe Asp Gly Arg 
        115                 120                 125             


Leu Val Lys Lys Ile Trp Val Pro Asp Met Phe Phe Val His Ser Lys 
    130                 135                 140                 


Arg Ser Phe Ile His Asp Thr Thr Thr Asp Asn Val Met Leu Arg Val 
145                 150                 155                 160 


Gln Pro Asp Gly Lys Val Leu Tyr Ser Leu Arg Val Thr Val Thr Ala 
                165                 170                 175     


Met Cys Asn Met Asp Phe Ser Arg Phe Pro Leu Asp Thr Gln Thr Cys 
            180                 185                 190         


Ser Leu Glu Ile Glu Ser Tyr Ala Tyr Thr Glu Asp Asp Leu Met Leu 
        195                 200                 205             


Tyr Trp Lys Lys Gly Asn Asp Ser Leu Lys Thr Asp Glu Arg Ile Ser 
    210                 215                 220                 


Leu Ser Gln Phe Leu Ile Gln Glu Phe His Thr Thr Thr Lys Leu Ala 
225                 230                 235                 240 


Phe Tyr Ser Ser Thr Gly Trp Tyr Asn Arg Leu Tyr Ile Asn Phe Thr 
                245                 250                 255     


Leu Arg Arg His Ile 
            260     


<210>  2162
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  2162

Ile Val Gly Gly His Glu Ala Gln Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Ser Leu Gln Met Arg Gly Asn Pro Gly Ser His Phe Cys Gly Gly Thr 
            20                  25                  30          


Leu Ile His Pro Ser Phe Val Leu Thr Ala Ala His Cys Leu Arg Asp 
        35                  40                  45              


Ile Pro Gln Arg Leu Val Asn Val Val Leu Gly Ala His Asn Val Arg 
    50                  55                  60                  


Thr Gln Glu Pro Thr Gln Gln His Phe Ser Val Ala Gln Val Phe Leu 
65                  70                  75                  80  


Asn Asn Tyr Asp Ala Glu Asn Lys Leu Asn Asp Val Leu Leu Ile Gln 
                85                  90                  95      


Leu Ser Ser Pro Ala Asn Leu Ser Ala Ser Val Ala Thr Val Gln Leu 
            100                 105                 110         


Pro Gln Gln Asp Gln Pro Val Pro His Gly Thr Gln Cys Leu Ala Met 
        115                 120                 125             


Gly Trp Gly Arg Val Gly Ala His Asp Pro Pro Ala Gln Val Leu Gln 
    130                 135                 140                 


Glu Leu Asn Val Thr Val Val Thr Phe Phe Cys Arg Pro His Asn Ile 
145                 150                 155                 160 


Cys Thr Phe Val Pro Arg Arg Lys Ala Gly Ile Cys Phe Gly Asp Ser 
                165                 170                 175     


Gly Gly Pro Leu Ile Cys Asp Gly Ile Ile Gln Gly Ile Asp Ser Phe 
            180                 185                 190         


Val Ile Trp Gly Cys Ala Thr Arg Leu Phe Pro Asp Phe Phe Thr Arg 
        195                 200                 205             


Val Ala Leu Tyr Val Asp Trp Ile Arg Ser Thr Leu Arg 
    210                 215                 220     


<210>  2163
<211>  298
<212>  PRT
<213>  Homo Sapiens

<400>  2163

Tyr Leu Glu Leu Arg Glu Ala Ala Asp Tyr Asp Pro Phe Leu Leu Phe 
1               5                   10                  15      


Ser Ala Asn Leu Lys Arg Glu Leu Ala Gly Glu Gln Pro Tyr Arg Arg 
            20                  25                  30          


Ala Leu Arg Cys Leu Asp Met Leu Ser Leu Gln Gly Gln Phe Thr Phe 
        35                  40                  45              


Thr Ala Asp Arg Pro Gln Leu His Cys Ala Ala Phe Phe Ile Ser Glu 
    50                  55                  60                  


Pro Glu Glu Phe Ile Thr Ile His Tyr Asp Gln Val Ser Ile Asp Cys 
65                  70                  75                  80  


Gln Gly Gly Asp Phe Leu Lys Val Phe Asp Gly Trp Ile Leu Lys Gly 
                85                  90                  95      


Glu Lys Phe Pro Ser Ser Gln Asp His Pro Leu Pro Ser Ala Glu Arg 
            100                 105                 110         


Tyr Ile Asp Phe Cys Glu Ser Gly Leu Ser Arg Arg Ser Ile Arg Ser 
        115                 120                 125             


Ser Gln Asn Val Ala Met Ile Phe Phe Arg Val His Glu Pro Gly Asn 
    130                 135                 140                 


Gly Phe Thr Leu Thr Ile Lys Thr Asp Pro Asn Leu Phe Pro Cys Asn 
145                 150                 155                 160 


Val Ile Ser Gln Thr Pro Asn Gly Lys Phe Thr Leu Val Val Pro His 
                165                 170                 175     


Gln His Arg Asn Cys Ser Phe Ser Ile Ile Tyr Pro Val Val Ile Lys 
            180                 185                 190         


Ile Ser Asp Leu Thr Leu Gly His Val Asn Gly Leu Gln Leu Lys Lys 
        195                 200                 205             


Ser Ser Ala Gly Cys Glu Gly Ile Gly Asp Phe Val Glu Leu Leu Gly 
    210                 215                 220                 


Gly Thr Gly Leu Asp Pro Ser Lys Met Thr Pro Leu Ala Asp Leu Cys 
225                 230                 235                 240 


Tyr Pro Phe His Gly Pro Ala Gln Met Lys Val Gly Cys Asp Asn Thr 
                245                 250                 255     


Val Val Arg Met Val Ser Ser Gly Lys His Val Asn Arg Val Thr Phe 
            260                 265                 270         


Glu Tyr Arg Gln Leu Glu Pro Tyr Glu Leu Glu Asn Pro Asn Gly Asn 
        275                 280                 285             


Ser Ile Gly Glu Phe Cys Leu Ser Gly Leu 
    290                 295             


<210>  2164
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  2164

Arg Cys Pro Gly Cys Gly Gln Gly Val Gln Ala Gly Cys Pro Gly Gly 
1               5                   10                  15      


Cys Val Glu Glu Glu Asp Gly Gly Ser Pro Ala Glu Gly Cys Ala Glu 
            20                  25                  30          


Ala Glu Gly Cys Leu Arg Arg Glu Gly Gln Glu Cys Gly Val Tyr Thr 
        35                  40                  45              


Pro Asn Cys Ala Pro Gly Leu Gln Cys His Pro Pro Lys Asp Asp Glu 
    50                  55                  60                  


Ala Pro Leu Arg Ala Leu Leu Leu Gly Arg Gly Arg Cys Leu Pro Ala 
65                  70                  75                  80  


Arg Ala Pro Ala Val Ala Glu Glu Asn Pro Lys Glu Ser Lys Pro Gln 
                85                  90                  95      


Ala Gly Thr Ala Arg Pro Gln Asp Val Asn Arg Arg Asp Gln Gln Arg 
            100                 105                 110         


Asn Pro Gly Thr Ser Thr Thr Pro Ser Gln Pro Asn Ser Ala Gly Val 
        115                 120                 125             


Gln Asp Thr Glu Met Gly Pro Cys Arg Arg His Leu Asp Ser Val Leu 
    130                 135                 140                 


Gln Gln Leu Gln Thr Glu Val Tyr Arg Gly Ala Gln Thr Leu Tyr Val 
145                 150                 155                 160 


Pro Asn Cys Asp His Arg Gly Phe Tyr Arg Lys Arg Gln Cys Arg Ser 
                165                 170                 175     


Ser Gln Gly Gln Arg Arg Gly Pro Cys Trp Cys Val Asp Arg Met Gly 
            180                 185                 190         


Lys Ser Leu Pro Gly Ser Pro Asp Gly Asn Gly Ser Ser Ser Cys Pro 
        195                 200                 205             


Thr Gly Ser Ser Gly 
    210             


<210>  2165
<211>  252
<212>  PRT
<213>  Homo Sapiens

<400>  2165

Leu Gly Ser Phe Val His Cys Glu Pro Cys Asp Glu Lys Ala Leu Ser 
1               5                   10                  15      


Met Cys Pro Pro Ser Pro Leu Gly Cys Glu Leu Val Lys Glu Pro Gly 
            20                  25                  30          


Cys Gly Cys Cys Met Thr Cys Ala Leu Ala Glu Gly Gln Ser Cys Gly 
        35                  40                  45              


Val Tyr Thr Glu Arg Cys Ala Gln Gly Leu Arg Cys Leu Pro Arg Gln 
    50                  55                  60                  


Asp Glu Glu Lys Pro Leu His Ala Leu Leu His Gly Arg Gly Val Cys 
65                  70                  75                  80  


Leu Asn Glu Lys Ser Tyr Arg Glu Gln Val Lys Ile Glu Arg Asp Ser 
                85                  90                  95      


Arg Glu His Glu Glu Pro Thr Thr Ser Glu Met Ala Glu Glu Thr Tyr 
            100                 105                 110         


Ser Pro Lys Ile Phe Arg Pro Lys His Thr Arg Ile Ser Glu Leu Lys 
        115                 120                 125             


Ala Glu Ala Val Lys Lys Asp Arg Arg Lys Lys Leu Thr Gln Ser Lys 
    130                 135                 140                 


Phe Val Gly Gly Ala Glu Asn Thr Ala His Pro Arg Ile Ile Ser Ala 
145                 150                 155                 160 


Pro Glu Met Arg Gln Glu Ser Glu Gln Gly Pro Cys Arg Arg His Met 
                165                 170                 175     


Glu Ala Ser Leu Gln Glu Leu Lys Ala Ser Pro Arg Met Val Pro Arg 
            180                 185                 190         


Ala Val Tyr Leu Pro Asn Cys Asp Arg Lys Gly Phe Tyr Lys Arg Lys 
        195                 200                 205             


Gln Cys Lys Pro Ser Arg Gly Arg Lys Arg Gly Ile Cys Trp Cys Val 
    210                 215                 220                 


Asp Lys Tyr Gly Met Lys Leu Pro Gly Met Glu Tyr Val Asp Gly Asp 
225                 230                 235                 240 


Phe Gln Cys His Thr Phe Asp Ser Ser Asn Val Glu 
                245                 250         


<210>  2166
<211>  260
<212>  PRT
<213>  Homo Sapiens

<400>  2166

Leu Lys Ile Ala Ala Phe Asn Ile Gln Thr Phe Gly Glu Thr Lys Met 
1               5                   10                  15      


Ser Asn Ala Thr Leu Val Ser Tyr Ile Val Gln Ile Leu Ser Arg Tyr 
            20                  25                  30          


Asp Ile Ala Leu Val Gln Glu Val Arg Asp Ser His Leu Thr Ala Val 
        35                  40                  45              


Gly Lys Leu Leu Asp Asn Leu Asn Gln Asp Ala Pro Asp Thr Tyr His 
    50                  55                  60                  


Tyr Val Val Ser Glu Pro Leu Gly Arg Asn Ser Tyr Lys Glu Arg Tyr 
65                  70                  75                  80  


Leu Phe Val Tyr Arg Pro Asp Gln Val Ser Ala Val Asp Ser Tyr Tyr 
                85                  90                  95      


Tyr Asp Asp Gly Cys Glu Pro Cys Gly Asn Asp Thr Phe Asn Arg Glu 
            100                 105                 110         


Pro Ala Ile Val Arg Phe Phe Ser Arg Phe Thr Glu Val Arg Glu Phe 
        115                 120                 125             


Ala Ile Val Pro Leu His Ala Ala Pro Gly Asp Ala Val Ala Glu Ile 
    130                 135                 140                 


Asp Ala Leu Tyr Asp Val Tyr Leu Asp Val Gln Glu Lys Trp Gly Leu 
145                 150                 155                 160 


Glu Asp Val Met Leu Met Gly Asp Phe Asn Ala Gly Cys Ser Tyr Val 
                165                 170                 175     


Arg Pro Ser Gln Trp Ser Ser Ile Arg Leu Trp Thr Ser Pro Thr Phe 
            180                 185                 190         


Gln Trp Leu Ile Pro Asp Ser Ala Asp Thr Thr Ala Thr Pro Thr His 
        195                 200                 205             


Cys Ala Tyr Asp Arg Ile Val Val Ala Gly Met Leu Leu Arg Gly Ala 
    210                 215                 220                 


Val Val Pro Asp Ser Ala Leu Pro Phe Asn Phe Gln Ala Ala Tyr Gly 
225                 230                 235                 240 


Leu Ser Asp Gln Leu Ala Gln Ala Ile Ser Asp His Tyr Pro Val Glu 
                245                 250                 255     


Val Met Leu Lys 
            260 


<210>  2167
<211>  407
<212>  PRT
<213>  Homo Sapiens

<400>  2167

Ser Gln Val Ser Gln Asn Cys His Asn Gly Ser Tyr Glu Ile Ser Val 
1               5                   10                  15      


Leu Met Met Gly Asn Ser Ala Phe Ala Glu Pro Leu Lys Asn Leu Glu 
            20                  25                  30          


Asp Ala Val Asn Glu Gly Leu Glu Ile Val Arg Gly Arg Leu Gln Asn 
        35                  40                  45              


Ala Gly Leu Asn Val Thr Val Asn Ala Thr Phe Met Tyr Ser Asp Gly 
    50                  55                  60                  


Leu Ile His Asn Ser Gly Asp Cys Arg Ser Ser Thr Cys Glu Gly Leu 
65                  70                  75                  80  


Asp Leu Leu Arg Lys Ile Ser Asn Ala Gln Arg Met Gly Cys Val Leu 
                85                  90                  95      


Ile Gly Pro Ser Cys Thr Tyr Ser Thr Phe Gln Met Tyr Leu Asp Thr 
            100                 105                 110         


Glu Leu Ser Tyr Pro Met Ile Ser Ala Gly Ser Phe Gly Leu Ser Cys 
        115                 120                 125             


Asp Tyr Lys Glu Thr Leu Thr Arg Leu Met Ser Pro Ala Arg Lys Leu 
    130                 135                 140                 


Met Tyr Phe Leu Val Asn Phe Trp Lys Thr Asn Asp Leu Pro Phe Lys 
145                 150                 155                 160 


Thr Tyr Ser Trp Ser Thr Ser Tyr Val Tyr Lys Asn Gly Thr Glu Thr 
                165                 170                 175     


Glu Asp Cys Phe Trp Tyr Leu Asn Ala Leu Glu Ala Ser Val Ser Tyr 
            180                 185                 190         


Phe Ser His Glu Leu Gly Phe Lys Val Val Leu Arg Gln Asp Lys Glu 
        195                 200                 205             


Phe Gln Asp Ile Leu Met Asp His Asn Arg Lys Ser Asn Val Ile Ile 
    210                 215                 220                 


Met Cys Gly Gly Pro Glu Phe Leu Tyr Lys Leu Lys Gly Asp Arg Ala 
225                 230                 235                 240 


Val Ala Glu Asp Ile Val Ile Ile Leu Val Asp Leu Phe Asn Asp Gln 
                245                 250                 255     


Tyr Leu Glu Asp Asn Val Thr Ala Pro Asp Tyr Met Lys Asn Val Leu 
            260                 265                 270         


Val Leu Thr Leu Ser Pro Gly Asn Ser Leu Leu Asn Ser Ser Phe Ser 
        275                 280                 285             


Arg Asn Leu Ser Pro Thr Lys Arg Asp Phe Ala Leu Ala Tyr Leu Asn 
    290                 295                 300                 


Gly Ile Leu Leu Phe Gly His Met Leu Lys Ile Phe Leu Glu Asn Gly 
305                 310                 315                 320 


Glu Asn Ile Thr Thr Pro Lys Phe Ala His Ala Phe Arg Asn Leu Thr 
                325                 330                 335     


Phe Glu Gly Tyr Asp Gly Pro Val Thr Leu Asp Asp Trp Gly Asp Val 
            340                 345                 350         


Asp Ser Thr Met Val Leu Leu Tyr Thr Ser Val Asp Thr Lys Lys Tyr 
        355                 360                 365             


Lys Val Leu Leu Thr Tyr Asp Thr His Val Asn Lys Thr Tyr Pro Val 
    370                 375                 380                 


Asp Met Ser Pro Thr Phe Thr Trp Lys Asn Ser Lys Leu Pro Asn Asp 
385                 390                 395                 400 


Ile Thr Gly Arg Gly Pro Gln 
                405         


<210>  2168
<211>  244
<212>  PRT
<213>  Homo Sapiens

<400>  2168

Gln Pro Asn Glu Leu Ser Gly Ser Ile Asp His Gln Thr Ser Val Gln 
1               5                   10                  15      


Gln Leu Pro Gly Glu Phe Phe Ser Leu Glu Asn Pro Ser Asp Ala Glu 
            20                  25                  30          


Ala Leu Tyr Glu Thr Ser Ser Gly Leu Asn Thr Leu Ser Glu His Gly 
        35                  40                  45              


Ser Ser Glu His Gly Ser Ser Lys His Thr Val Ala Glu His Thr Ser 
    50                  55                  60                  


Gly Glu His Ala Glu Ser Glu His Ala Ser Gly Glu Pro Ala Ala Thr 
65                  70                  75                  80  


Glu His Ala Glu Gly Glu His Thr Val Gly Glu Gln Pro Ser Gly Glu 
                85                  90                  95      


Gln Pro Ser Gly Glu His Leu Ser Gly Glu Gln Pro Leu Ser Glu Leu 
            100                 105                 110         


Glu Ser Gly Glu Gln Pro Ser Asp Glu Gln Pro Ser Gly Glu His Gly 
        115                 120                 125             


Ser Gly Glu Gln Pro Ser Gly Glu Gln Ala Ser Gly Glu Gln Pro Ser 
    130                 135                 140                 


Gly Glu His Ala Ser Gly Glu Gln Ala Ser Gly Ala Pro Ile Ser Ser 
145                 150                 155                 160 


Thr Ser Thr Gly Thr Ile Leu Asn Cys Tyr Thr Cys Ala Tyr Met Asn 
                165                 170                 175     


Asp Gln Gly Lys Cys Leu Arg Gly Glu Gly Thr Cys Ile Thr Gln Asn 
            180                 185                 190         


Ser Gln Gln Cys Met Leu Lys Lys Ile Phe Glu Gly Gly Lys Leu Gln 
        195                 200                 205             


Phe Met Val Gln Gly Cys Glu Asn Met Cys Pro Ser Met Asn Leu Phe 
    210                 215                 220                 


Ser His Gly Thr Arg Met Gln Ile Ile Cys Cys Arg Asn Gln Ser Phe 
225                 230                 235                 240 


Cys Asn Lys Ile 
                


<210>  2169
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  2169

Ala Thr Gly Ala Glu Gly Lys Arg Lys Leu Gln Ile Gly Val Lys Lys 
1               5                   10                  15      


Arg Val Asp His Cys Pro Ile Lys Ser Arg Lys Gly Asp Val Leu His 
            20                  25                  30          


Met His Tyr Thr Gly Lys Leu Glu Asp Gly Thr Glu Phe Asp Ser Ser 
        35                  40                  45              


Leu Pro Gln Asn Gln Pro Phe Val Phe Ser Leu Gly Thr Gly Gln Val 
    50                  55                  60                  


Ile Lys Gly Trp Asp Gln Gly Leu Leu Gly Met Cys Glu Gly Glu Lys 
65                  70                  75                  80  


Arg Lys Leu Val Ile Pro Ser Glu Leu Gly Tyr Gly Glu Arg Gly Ala 
                85                  90                  95      


Pro Pro Lys Ile Pro Gly Gly Ala Thr Leu Val Phe Glu Val Glu Leu 
            100                 105                 110         


Leu Lys Ile Glu Arg Arg Thr Glu Leu 
        115                 120     


<210>  2170
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  2170

Ala Ile Leu Gly Arg Ser Glu Thr Gln Glu Cys Leu Phe Phe Asn Ala 
1               5                   10                  15      


Asn Trp Glu Lys Asp Arg Thr Asn Gln Thr Gly Val Glu Pro Cys Tyr 
            20                  25                  30          


Gly Asp Lys Asp Lys Arg Arg His Cys Phe Ala Thr Trp Lys Asn Ile 
        35                  40                  45              


Ser Gly Ser Ile Glu Ile Val Lys Gln Gly Cys Trp Leu Asp Asp Ile 
    50                  55                  60                  


Asn Cys Tyr Asp Arg Thr Asp Cys Val Glu Lys Lys Asp Ser Pro Glu 
65                  70                  75                  80  


Val Tyr Phe Cys Cys Cys Glu Gly Asn Met Cys Asn Glu Lys Phe Ser 
                85                  90                  95      


Tyr Phe Pro Glu Met Glu Val Thr Gln Pro Thr Ser Asn Pro Val Thr 
            100                 105                 110         


Pro Lys Pro Pro 
        115     


<210>  2171
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  2171

Ala Lys Leu Ile Ala Leu Thr Leu Leu Gly Met Gly Leu Ala Leu Phe 
1               5                   10                  15      


Arg Asn His Gln Ser Ser Tyr Gln Thr Arg Leu Asn Ala Leu Arg Glu 
            20                  25                  30          


Val Gln Pro Val Glu Leu Pro Asn Cys Asn Leu Val Lys Gly Ile Glu 
        35                  40                  45              


Thr Gly Ser Glu Asp Leu Glu Ile Leu Pro Asn Gly Leu Ala Phe Ile 
    50                  55                  60                  


Ser Ser Gly Leu Lys Tyr Pro Gly Ile Lys Ser Phe Asn Pro Asn Ser 
65                  70                  75                  80  


Pro Gly Lys Ile Leu Leu Met Asp Leu Asn Glu Glu Asp Pro Thr Val 
                85                  90                  95      


Leu Glu Leu Gly Ile Thr Gly Ser Lys Phe Asp Val Ser Ser Phe Asn 
            100                 105                 110         


Pro His Gly Ile Ser Thr Phe Thr Asp Glu Asp Asn Ala Met Tyr Leu 
        115                 120                 125             


Leu Val Val Asn His Pro Asp Ala Lys Ser Thr Val Glu Leu Phe Lys 
    130                 135                 140                 


Phe Gln Glu Glu Glu Lys Ser Leu Leu His Leu Lys Thr Ile Arg His 
145                 150                 155                 160 


Lys Leu Leu Pro Asn Leu Asn Asp Ile Val Ala Val Gly Pro Glu His 
                165                 170                 175     


Phe Tyr Gly Thr Asn Asp His Tyr Phe Leu Asp Pro Tyr Leu Gln Ser 
            180                 185                 190         


Trp Glu Met Tyr Leu Gly Leu Ala Trp Ser Tyr Val Val Tyr Tyr Ser 
        195                 200                 205             


Pro Ser Glu Val Arg Val Val Ala Glu Gly Phe Asp Phe Ala Asn Gly 
    210                 215                 220                 


Ile Asn Ile Ser Pro Asp Gly Lys Tyr Val Tyr Ile Ala Glu Leu Leu 
225                 230                 235                 240 


Ala His Lys Ile His Val Tyr Glu Lys His Ala Asn Trp Thr Leu Thr 
                245                 250                 255     


Pro Leu Lys Ser Leu Asp Phe Asn Thr Leu Val Asp Asn Ile Ser Val 
            260                 265                 270         


Asp Pro Glu Thr Gly Asp Leu Trp Val Gly Cys His Pro Asn Gly Met 
        275                 280                 285             


Lys Ile Phe Phe Tyr Asp Ser Glu Asn Pro Pro Ala Ser Glu Val Leu 
    290                 295                 300                 


Arg Ile Gln Asn Ile Leu Thr Glu Glu Pro Lys Val Thr Gln Val Tyr 
305                 310                 315                 320 


Ala Glu Asn Gly Thr Val Leu Gln Gly Ser Thr Val Ala Ser Val Tyr 
                325                 330                 335     


Lys Gly Lys Leu Leu Ile Gly Thr Val Phe His Lys Ala Leu Tyr Cys 
            340                 345                 350         


Glu Leu 
        


<210>  2172
<211>  399
<212>  PRT
<213>  Homo Sapiens

<400>  2172

Ser Thr Gln Thr Gln Ser Ser Cys Ser Val Pro Ser Ala Gln Glu Pro 
1               5                   10                  15      


Leu Val Asn Gly Ile Gln Val Leu Met Glu Asn Ser Val Thr Ser Ser 
            20                  25                  30          


Ala Tyr Pro Asn Pro Ser Ile Leu Ile Ala Met Asn Leu Ala Gly Ala 
        35                  40                  45              


Tyr Asn Leu Lys Ala Gln Lys Leu Leu Thr Tyr Gln Leu Met Ser Ser 
    50                  55                  60                  


Asp Asn Asn Asp Leu Thr Ile Gly Gln Leu Gly Leu Thr Ile Met Ala 
65                  70                  75                  80  


Leu Thr Ser Ser Cys Arg Asp Pro Gly Asp Lys Val Ser Ile Leu Gln 
                85                  90                  95      


Arg Gln Met Glu Asn Trp Ala Pro Ser Ser Pro Asn Ala Glu Ala Ser 
            100                 105                 110         


Ala Phe Tyr Gly Pro Ser Leu Ala Ile Leu Ala Leu Cys Gln Lys Asn 
        115                 120                 125             


Ser Glu Ala Thr Leu Pro Ile Ala Val Arg Phe Ala Lys Thr Leu Leu 
    130                 135                 140                 


Ala Asn Ser Ser Pro Phe Asn Val Asp Thr Gly Ala Met Ala Thr Leu 
145                 150                 155                 160 


Ala Leu Thr Cys Met Tyr Asn Lys Ile Pro Val Gly Ser Glu Glu Gly 
                165                 170                 175     


Tyr Arg Ser Leu Phe Gly Gln Val Leu Lys Asp Ile Val Glu Lys Ile 
            180                 185                 190         


Ser Met Lys Ile Lys Asp Asn Gly Ile Ile Gly Asp Ile Tyr Ser Thr 
        195                 200                 205             


Gly Leu Ala Met Gln Ala Leu Ser Val Thr Pro Glu Pro Ser Lys Lys 
    210                 215                 220                 


Glu Trp Asn Cys Lys Lys Thr Thr Asp Met Ile Leu Asn Glu Ile Lys 
225                 230                 235                 240 


Gln Gly Lys Phe His Asn Pro Met Ser Ile Ala Gln Ile Leu Pro Ser 
                245                 250                 255     


Leu Lys Gly Lys Thr Tyr Leu Asp Val Pro Gln Val Thr Cys Ser Pro 
            260                 265                 270         


Asp His Glu Val Gln Pro Thr Leu Pro Ser Asn Pro Gly Pro Gly Pro 
        275                 280                 285             


Thr Ser Ala Ser Asn Ile Thr Val Ile Tyr Thr Ile Asn Asn Gln Leu 
    290                 295                 300                 


Arg Gly Val Glu Leu Leu Phe Asn Glu Thr Ile Asn Val Ser Val Lys 
305                 310                 315                 320 


Ser Gly Ser Val Leu Leu Val Val Leu Glu Glu Ala Gln Arg Lys Asn 
                325                 330                 335     


Pro Met Phe Lys Phe Glu Thr Thr Met Thr Ser Trp Gly Leu Val Val 
            340                 345                 350         


Ser Ser Ile Asn Asn Ile Ala Glu Asn Val Asn His Lys Thr Tyr Trp 
        355                 360                 365             


Gln Phe Leu Ser Gly Val Thr Pro Leu Asn Glu Gly Val Ala Asp Tyr 
    370                 375                 380                 


Ile Pro Phe Asn His Glu His Ile Thr Ala Asn Phe Thr Gln Tyr 
385                 390                 395                 


<210>  2173
<211>  173
<212>  PRT
<213>  Homo Sapiens

<400>  2173

Ala Val Met Pro Pro Thr Pro Pro Pro Gln Gly Glu Tyr Leu Pro Asp 
1               5                   10                  15      


Met Gly Leu Gly Ile Asp Gly Val Lys Pro Pro His Ala Tyr Gly Ala 
            20                  25                  30          


Lys Lys Gly Lys Asn Gly Gly Pro Ala Tyr Glu Met Pro Ala Phe Thr 
        35                  40                  45              


Ala Glu Leu Thr Ala Pro Phe Pro Pro Val Gly Ala Pro Val Lys Phe 
    50                  55                  60                  


Asn Lys Leu Leu Tyr Asn Gly Arg Gln Asn Tyr Asn Pro Gln Thr Gly 
65                  70                  75                  80  


Ile Phe Thr Cys Glu Val Pro Gly Val Tyr Tyr Phe Ala Tyr His Val 
                85                  90                  95      


His Cys Lys Gly Gly Asn Val Trp Val Ala Leu Phe Lys Asn Asn Glu 
            100                 105                 110         


Pro Val Met Tyr Thr Tyr Asp Glu Tyr Lys Lys Gly Phe Leu Asp Gln 
        115                 120                 125             


Ala Ser Gly Ser Ala Val Leu Leu Leu Arg Pro Gly Asp Arg Val Phe 
    130                 135                 140                 


Leu Gln Met Pro Ser Glu Gln Ala Ala Gly Leu Tyr Ala Gly Gln Tyr 
145                 150                 155                 160 


Val His Ser Ser Phe Ser Gly Tyr Leu Leu Tyr Pro Met 
                165                 170             


<210>  2174
<211>  400
<212>  PRT
<213>  Homo Sapiens

<400>  2174

Glu Pro Ala Val Tyr Phe Lys Glu Gln Phe Leu Asp Gly Asp Gly Trp 
1               5                   10                  15      


Thr Ser Arg Trp Ile Glu Ser Lys His Lys Ser Asp Phe Gly Lys Phe 
            20                  25                  30          


Val Leu Ser Ser Gly Lys Phe Tyr Gly Asp Glu Glu Lys Asp Lys Gly 
        35                  40                  45              


Leu Gln Thr Ser Gln Asp Ala Arg Phe Tyr Ala Leu Ser Ala Ser Phe 
    50                  55                  60                  


Glu Pro Phe Ser Asn Lys Gly Gln Thr Leu Val Val Gln Phe Thr Val 
65                  70                  75                  80  


Lys His Glu Gln Asn Ile Asp Cys Gly Gly Gly Tyr Val Lys Leu Phe 
                85                  90                  95      


Pro Asn Ser Leu Asp Gln Thr Asp Met His Gly Asp Ser Glu Tyr Asn 
            100                 105                 110         


Ile Met Phe Gly Pro Asp Ile Cys Gly Pro Gly Thr Lys Lys Val His 
        115                 120                 125             


Val Ile Phe Asn Tyr Lys Gly Lys Asn Val Leu Ile Asn Lys Asp Ile 
    130                 135                 140                 


Arg Cys Lys Asp Asp Glu Phe Thr His Leu Tyr Thr Leu Ile Val Arg 
145                 150                 155                 160 


Pro Asp Asn Thr Tyr Glu Val Lys Ile Asp Asn Ser Gln Val Glu Ser 
                165                 170                 175     


Gly Ser Leu Glu Asp Asp Trp Asp Phe Leu Pro Pro Lys Lys Ile Lys 
            180                 185                 190         


Asp Pro Asp Ala Ser Lys Pro Glu Asp Trp Asp Glu Arg Ala Lys Ile 
        195                 200                 205             


Asp Asp Pro Thr Asp Ser Lys Pro Glu Asp Trp Asp Lys Pro Glu His 
    210                 215                 220                 


Ile Pro Asp Pro Asp Ala Lys Lys Pro Glu Asp Trp Asp Glu Glu Met 
225                 230                 235                 240 


Asp Gly Glu Trp Glu Pro Pro Val Ile Gln Asn Pro Glu Tyr Lys Gly 
                245                 250                 255     


Glu Trp Lys Pro Arg Gln Ile Asp Asn Pro Asp Tyr Lys Gly Thr Trp 
            260                 265                 270         


Ile His Pro Glu Ile Asp Asn Pro Glu Tyr Ser Pro Asp Pro Ser Ile 
        275                 280                 285             


Tyr Ala Tyr Asp Asn Phe Gly Val Leu Gly Leu Asp Leu Trp Gln Val 
    290                 295                 300                 


Lys Ser Gly Thr Ile Phe Asp Asn Phe Leu Ile Thr Asn Asp Glu Ala 
305                 310                 315                 320 


Tyr Ala Glu Glu Phe Gly Asn Glu Thr Trp Gly Val Thr Lys Ala Ala 
                325                 330                 335     


Glu Lys Gln Met Lys Asp Lys Gln Asp Glu Glu Gln Arg Leu Lys Glu 
            340                 345                 350         


Glu Glu Glu Asp Lys Lys Arg Lys Glu Glu Glu Glu Ala Glu Asp Lys 
        355                 360                 365             


Glu Asp Asp Glu Asp Lys Asp Glu Asp Glu Glu Asp Glu Glu Asp Lys 
    370                 375                 380                 


Glu Glu Asp Glu Glu Glu Asp Val Pro Gly Gln Ala Lys Asp Glu Leu 
385                 390                 395                 400 


<210>  2175
<211>  442
<212>  PRT
<213>  Homo Sapiens

<400>  2175

Asp Pro Val Leu Cys Phe Thr Gln Tyr Glu Glu Ser Ser Gly Lys Cys 
1               5                   10                  15      


Lys Gly Leu Leu Gly Gly Gly Val Ser Val Glu Asp Cys Cys Leu Asn 
            20                  25                  30          


Thr Ala Phe Ala Tyr Gln Lys Arg Ser Gly Gly Leu Cys Gln Pro Cys 
        35                  40                  45              


Arg Ser Pro Arg Trp Ser Leu Trp Ser Thr Trp Ala Pro Cys Ser Val 
    50                  55                  60                  


Thr Cys Ser Glu Gly Ser Gln Leu Arg Tyr Arg Arg Cys Val Gly Trp 
65                  70                  75                  80  


Asn Gly Gln Cys Ser Gly Lys Val Ala Pro Gly Thr Leu Glu Trp Gln 
                85                  90                  95      


Leu Gln Ala Cys Glu Asp Gln Gln Cys Cys Pro Glu Met Gly Gly Trp 
            100                 105                 110         


Ser Gly Trp Gly Pro Trp Glu Pro Cys Ser Val Thr Cys Ser Lys Gly 
        115                 120                 125             


Thr Arg Thr Arg Arg Arg Ala Cys Asn His Pro Ala Pro Lys Cys Gly 
    130                 135                 140                 


Gly His Cys Pro Gly Gln Ala Gln Glu Ser Glu Ala Cys Asp Thr Gln 
145                 150                 155                 160 


Gln Val Cys Pro Thr His Gly Ala Trp Ala Thr Trp Gly Pro Trp Thr 
                165                 170                 175     


Pro Cys Ser Ala Ser Cys His Gly Gly Pro His Glu Pro Lys Glu Thr 
            180                 185                 190         


Arg Ser Arg Lys Cys Ser Ala Pro Glu Pro Ser Gln Lys Pro Pro Gly 
        195                 200                 205             


Lys Pro Cys Pro Gly Leu Ala Tyr Glu Gln Arg Arg Cys Thr Gly Leu 
    210                 215                 220                 


Pro Pro Cys Pro Val Ala Gly Gly Trp Gly Pro Trp Gly Pro Val Ser 
225                 230                 235                 240 


Pro Cys Pro Val Thr Cys Gly Leu Gly Gln Thr Met Glu Gln Arg Thr 
                245                 250                 255     


Cys Asn His Pro Val Pro Gln His Gly Gly Pro Phe Cys Ala Gly Asp 
            260                 265                 270         


Ala Thr Arg Thr His Ile Cys Asn Thr Ala Val Pro Cys Pro Val Asp 
        275                 280                 285             


Gly Glu Trp Asp Ser Trp Gly Glu Trp Ser Pro Cys Ile Arg Arg Asn 
    290                 295                 300                 


Met Lys Ser Ile Ser Cys Gln Glu Ile Pro Gly Gln Gln Ser Arg Gly 
305                 310                 315                 320 


Arg Thr Cys Arg Gly Arg Lys Phe Asp Gly His Arg Cys Ala Gly Gln 
                325                 330                 335     


Gln Gln Asp Ile Arg His Cys Tyr Ser Ile Gln His Cys Pro Leu Lys 
            340                 345                 350         


Gly Ser Trp Ser Glu Trp Ser Thr Trp Gly Leu Cys Met Pro Pro Cys 
        355                 360                 365             


Gly Pro Asn Pro Thr Arg Ala Arg Gln Arg Leu Cys Thr Pro Leu Leu 
    370                 375                 380                 


Pro Lys Tyr Pro Pro Thr Val Ser Met Val Glu Gly Gln Gly Glu Lys 
385                 390                 395                 400 


Asn Val Thr Phe Trp Gly Arg Pro Leu Pro Arg Cys Glu Glu Leu Gln 
                405                 410                 415     


Gly Gln Lys Leu Val Val Glu Glu Lys Arg Pro Cys Leu His Val Pro 
            420                 425                 430         


Ala Cys Lys Asp Pro Glu Glu Glu Glu Leu 
        435                 440         


<210>  2176
<211>  122
<212>  PRT
<213>  Homo Sapiens

<400>  2176

Gly Ser Ala Ser Ala Gln Ser Arg Thr Leu Ala Gly Gly Ile His Ala 
1               5                   10                  15      


Thr Asp Leu Asn Asp Lys Ser Val Gln Cys Ala Leu Asp Phe Ala Ile 
            20                  25                  30          


Ser Glu Tyr Asn Lys Val Ile Asn Lys Asp Glu Tyr Tyr Ser Arg Pro 
        35                  40                  45              


Leu Gln Val Met Ala Ala Tyr Gln Gln Ile Val Gly Gly Val Asn Tyr 
    50                  55                  60                  


Tyr Phe Asn Val Lys Phe Gly Arg Thr Thr Cys Thr Lys Ser Gln Pro 
65                  70                  75                  80  


Asn Leu Asp Asn Cys Pro Phe Asn Asp Gln Pro Lys Leu Lys Glu Glu 
                85                  90                  95      


Glu Phe Cys Ser Phe Gln Ile Asn Glu Val Pro Trp Glu Asp Lys Ile 
            100                 105                 110         


Ser Ile Leu Asn Tyr Lys Cys Arg Lys Val 
        115                 120         


<210>  2177
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  2177

Gln Ser Val Asn Asp Pro Gly Asn Met Ser Phe Val Lys Glu Thr Val 
1               5                   10                  15      


Asp Lys Leu Leu Lys Gly Tyr Asp Ile Arg Leu Arg Pro Asp Phe Gly 
            20                  25                  30          


Gly Pro Pro Val Cys Val Gly Met Asn Ile Asp Ile Ala Ser Ile Asp 
        35                  40                  45              


Met Val Ser Glu Val Asn Met Asp Tyr Thr Leu Thr Met Tyr Phe Gln 
    50                  55                  60                  


Gln Tyr Trp Arg Asp Lys Arg Leu Ala Tyr Ser Gly Ile Pro Leu Asn 
65                  70                  75                  80  


Leu Thr Leu Asp Asn Arg Val Ala Asp Gln Leu Trp Val Pro Asp Thr 
                85                  90                  95      


Tyr Phe Leu Asn Asp Lys Lys Ser Phe Val His Gly Val Thr Val Lys 
            100                 105                 110         


Asn Arg Met Ile Arg Leu His Pro Asp Gly Thr Val Leu Tyr Gly Leu 
        115                 120                 125             


Arg Ile Thr Thr Thr Ala Ala Cys Met Met Asp Leu Arg Arg Tyr Pro 
    130                 135                 140                 


Leu Asp Glu Leu Asn Cys Thr Leu Glu Ile Glu Ser Tyr Gly Tyr Thr 
145                 150                 155                 160 


Thr Asp Asp Ile Glu Phe Tyr Trp Arg Gly Gly Asp Lys Ala Val Thr 
                165                 170                 175     


Gly Val Glu Arg Ile Glu Leu Pro Gln Phe Ser Ile Val Glu His Arg 
            180                 185                 190         


Leu Val Ser Arg Asn Val Val Phe Ala Thr Gly Ala Tyr Pro Arg Leu 
        195                 200                 205             


Ser Leu Ser Phe Arg Leu Lys Arg Asn Ile Gly Tyr 
    210                 215                 220 


<210>  2178
<211>  240
<212>  PRT
<213>  Homo Sapiens

<400>  2178

Arg Lys Pro Lys Arg Lys Arg Trp Thr Gly Gln Val Glu Met Pro Lys 
1               5                   10                  15      


Pro Ser His Leu Tyr Lys Lys Asn Leu Asp Val Thr Lys Ile Arg Lys 
            20                  25                  30          


Gly Lys Pro Gln Gln Leu Leu Arg Val Asp Glu His Asp Phe Ser Met 
        35                  40                  45              


Arg Pro Ala Phe Gly Gly Pro Ala Ile Pro Val Gly Val Asp Val Gln 
    50                  55                  60                  


Val Glu Ser Leu Asp Ser Ile Ser Glu Val Asp Met Asp Phe Thr Met 
65                  70                  75                  80  


Thr Leu Tyr Leu Arg His Tyr Trp Lys Asp Glu Arg Leu Ala Phe Ser 
                85                  90                  95      


Ser Ala Ser Asn Lys Ser Met Thr Phe Asp Gly Arg Leu Val Lys Lys 
            100                 105                 110         


Ile Trp Val Pro Asp Val Phe Phe Val His Ser Lys Arg Ser Phe Thr 
        115                 120                 125             


His Asp Thr Thr Thr Asp Asn Ile Met Leu Arg Val Phe Pro Asp Gly 
    130                 135                 140                 


His Val Leu Tyr Ser Met Arg Ile Thr Val Thr Ala Met Cys Asn Met 
145                 150                 155                 160 


Asp Phe Ser His Phe Pro Leu Asp Ser Gln Thr Cys Ser Leu Glu Leu 
                165                 170                 175     


Glu Ser Tyr Ala Tyr Thr Asp Glu Asp Leu Met Leu Tyr Trp Lys Asn 
            180                 185                 190         


Gly Asp Glu Ser Leu Lys Thr Asp Glu Lys Ile Ser Leu Ser Gln Phe 
        195                 200                 205             


Leu Ile Gln Lys Phe His Thr Thr Ser Arg Leu Ala Phe Tyr Ser Ser 
    210                 215                 220                 


Thr Gly Trp Tyr Asn Arg Leu Tyr Ile Asn Phe Thr Leu Arg Arg His 
225                 230                 235                 240 


<210>  2179
<211>  576
<212>  PRT
<213>  Homo Sapiens

<400>  2179

Thr Arg Cys Pro Asp Gly Gln Phe Cys Pro Val Ala Cys Cys Leu Asp 
1               5                   10                  15      


Pro Gly Gly Ala Ser Tyr Ser Cys Cys Arg Pro Leu Leu Asp Lys Trp 
            20                  25                  30          


Pro Thr Thr Leu Ser Arg His Leu Gly Gly Pro Cys Gln Val Asp Ala 
        35                  40                  45              


His Cys Ser Ala Gly His Ser Cys Ile Phe Thr Val Ser Gly Thr Ser 
    50                  55                  60                  


Ser Cys Cys Pro Phe Pro Glu Ala Val Ala Cys Gly Asp Gly His His 
65                  70                  75                  80  


Cys Cys Pro Arg Gly Phe His Cys Ser Ala Asp Gly Arg Ser Cys Phe 
                85                  90                  95      


Gln Arg Ser Gly Asn Asn Ser Val Gly Ala Ile Gln Cys Pro Asp Ser 
            100                 105                 110         


Gln Phe Glu Cys Pro Asp Phe Ser Thr Cys Cys Val Met Val Asp Gly 
        115                 120                 125             


Ser Trp Gly Cys Cys Pro Met Pro Gln Ala Ser Cys Cys Glu Asp Arg 
    130                 135                 140                 


Val His Cys Cys Pro His Gly Ala Phe Cys Asp Leu Val His Thr Arg 
145                 150                 155                 160 


Cys Ile Thr Pro Thr Gly Thr His Pro Leu Ala Lys Lys Leu Pro Ala 
                165                 170                 175     


Gln Arg Thr Asn Arg Ala Val Ala Leu Ser Ser Ser Val Met Cys Pro 
            180                 185                 190         


Asp Ala Arg Ser Arg Cys Pro Asp Gly Ser Thr Cys Cys Glu Leu Pro 
        195                 200                 205             


Ser Gly Lys Tyr Gly Cys Cys Pro Met Pro Asn Ala Thr Cys Cys Ser 
    210                 215                 220                 


Asp His Leu His Cys Cys Pro Gln Asp Thr Val Cys Asp Leu Ile Gln 
225                 230                 235                 240 


Ser Lys Cys Leu Ser Lys Glu Asn Ala Thr Thr Asp Leu Leu Thr Lys 
                245                 250                 255     


Leu Pro Ala His Thr Val Gly Asp Val Lys Cys Asp Met Glu Val Ser 
            260                 265                 270         


Cys Pro Asp Gly Tyr Thr Cys Cys Arg Leu Gln Ser Gly Ala Trp Gly 
        275                 280                 285             


Cys Cys Pro Phe Thr Gln Ala Val Cys Cys Glu Asp His Ile His Cys 
    290                 295                 300                 


Cys Pro Ala Gly Phe Thr Cys Asp Thr Gln Lys Gly Thr Cys Glu Gln 
305                 310                 315                 320 


Gly Pro His Gln Val Pro Trp Met Glu Lys Ala Pro Ala His Leu Ser 
                325                 330                 335     


Leu Pro Asp Pro Gln Ala Leu Lys Arg Asp Val Pro Cys Asp Asn Val 
            340                 345                 350         


Ser Ser Cys Pro Ser Ser Asp Thr Cys Cys Gln Leu Thr Ser Gly Glu 
        355                 360                 365             


Trp Gly Cys Cys Pro Ile Pro Glu Ala Val Cys Cys Ser Asp His Gln 
    370                 375                 380                 


His Cys Cys Pro Gln Gly Tyr Thr Cys Val Ala Glu Gly Gln Cys Gln 
385                 390                 395                 400 


Arg Gly Ser Glu Ile Val Ala Gly Leu Glu Lys Met Pro Ala Arg Arg 
                405                 410                 415     


Ala Ser Leu Ser His Pro Arg Asp Ile Gly Cys Asp Gln His Thr Ser 
            420                 425                 430         


Cys Pro Val Gly Gln Thr Cys Cys Pro Ser Leu Gly Gly Ser Trp Ala 
        435                 440                 445             


Cys Cys Gln Leu Pro His Ala Val Cys Cys Glu Asp Arg Gln His Cys 
    450                 455                 460                 


Cys Pro Ala Gly Tyr Thr Cys Asn Val Lys Ala Arg Ser Cys Glu Lys 
465                 470                 475                 480 


Glu Val Val Ser Ala Gln Pro Ala Thr Phe Leu Ala Arg Ser Pro His 
                485                 490                 495     


Val Gly Val Lys Asp Val Glu Cys Gly Glu Gly His Phe Cys His Asp 
            500                 505                 510         


Asn Gln Thr Cys Cys Arg Asp Asn Arg Gln Gly Trp Ala Cys Cys Pro 
        515                 520                 525             


Tyr Arg Gln Gly Val Cys Cys Ala Asp Arg Arg His Cys Cys Pro Ala 
    530                 535                 540                 


Gly Phe Arg Cys Ala Ala Arg Gly Thr Lys Cys Leu Arg Arg Glu Ala 
545                 550                 555                 560 


Pro Arg Trp Asp Ala Pro Leu Arg Asp Pro Ala Leu Arg Gln Leu Leu 
                565                 570                 575     


<210>  2180
<211>  643
<212>  PRT
<213>  Homo Sapiens

<400>  2180

Ser Ala Leu Arg Asp Ser Ala Leu Asn Leu Phe Asn Asp Pro Met Trp 
1               5                   10                  15      


Asn Gln Gln Trp Tyr Leu Gln Asp Thr Arg Met Thr Ala Ala Leu Pro 
            20                  25                  30          


Lys Leu Asp Leu His Val Ile Pro Val Trp Gln Lys Gly Ile Thr Gly 
        35                  40                  45              


Lys Gly Val Val Ile Thr Val Leu Asp Asp Gly Leu Glu Trp Asn His 
    50                  55                  60                  


Thr Asp Ile Tyr Ala Asn Tyr Asp Pro Glu Ala Ser Tyr Asp Phe Asn 
65                  70                  75                  80  


Asp Asn Asp His Asp Pro Phe Pro Arg Tyr Asp Pro Thr Asn Glu Asn 
                85                  90                  95      


Lys His Gly Thr Arg Cys Ala Gly Glu Ile Ala Met Gln Ala Asn Asn 
            100                 105                 110         


His Lys Cys Gly Val Gly Val Ala Tyr Asn Ser Lys Val Gly Gly Ile 
        115                 120                 125             


Arg Met Leu Asp Gly Ile Val Thr Asp Ala Ile Glu Ala Ser Ser Ile 
    130                 135                 140                 


Gly Phe Asn Pro Gly His Val Asp Ile Tyr Ser Ala Ser Trp Gly Pro 
145                 150                 155                 160 


Asn Asp Asp Gly Lys Thr Val Glu Gly Pro Gly Arg Leu Ala Gln Lys 
                165                 170                 175     


Ala Phe Glu Tyr Gly Val Lys Gln Gly Arg Gln Gly Lys Gly Ser Ile 
            180                 185                 190         


Phe Val Trp Ala Ser Gly Asn Gly Gly Arg Gln Gly Asp Asn Cys Asp 
        195                 200                 205             


Cys Asp Gly Tyr Thr Asp Ser Ile Tyr Thr Ile Ser Ile Ser Ser Ala 
    210                 215                 220                 


Ser Gln Gln Gly Leu Ser Pro Trp Tyr Ala Glu Lys Cys Ser Ser Thr 
225                 230                 235                 240 


Leu Ala Thr Ser Tyr Ser Ser Gly Asp Tyr Thr Asp Gln Arg Ile Thr 
                245                 250                 255     


Ser Ala Asp Leu His Asn Asp Cys Thr Glu Thr His Thr Gly Thr Ser 
            260                 265                 270         


Ala Ser Ala Pro Leu Ala Ala Gly Ile Phe Ala Leu Ala Leu Glu Ala 
        275                 280                 285             


Asn Pro Asn Leu Thr Trp Arg Asp Met Gln His Leu Val Val Trp Thr 
    290                 295                 300                 


Ser Glu Tyr Asp Pro Leu Ala Asn Asn Pro Gly Trp Lys Lys Asn Gly 
305                 310                 315                 320 


Ala Gly Leu Met Val Asn Ser Arg Phe Gly Phe Gly Leu Leu Asn Ala 
                325                 330                 335     


Lys Ala Leu Val Asp Leu Ala Asp Pro Arg Thr Trp Arg Ser Val Pro 
            340                 345                 350         


Glu Lys Lys Glu Cys Val Val Lys Asp Asn Asp Phe Glu Pro Arg Ala 
        355                 360                 365             


Leu Lys Ala Asn Gly Glu Val Ile Ile Glu Ile Pro Thr Arg Ala Cys 
    370                 375                 380                 


Glu Gly Gln Glu Asn Ala Ile Lys Ser Leu Glu His Val Gln Phe Glu 
385                 390                 395                 400 


Ala Thr Ile Glu Tyr Ser Arg Arg Gly Asp Leu His Val Thr Leu Thr 
                405                 410                 415     


Ser Ala Ala Gly Thr Ser Thr Val Leu Leu Ala Glu Arg Glu Arg Asp 
            420                 425                 430         


Thr Ser Pro Asn Gly Phe Lys Asn Trp Asp Phe Met Ser Val His Thr 
        435                 440                 445             


Trp Gly Glu Asn Pro Ile Gly Thr Trp Thr Leu Arg Ile Thr Asp Met 
    450                 455                 460                 


Ser Gly Arg Ile Gln Asn Glu Gly Arg Ile Val Asn Trp Lys Leu Ile 
465                 470                 475                 480 


Leu His Gly Thr Ser Ser Gln Pro Glu His Met Lys Gln Pro Arg Val 
                485                 490                 495     


Tyr Thr Ser Tyr Asn Thr Val Gln Asn Asp Arg Arg Gly Val Glu Lys 
            500                 505                 510         


Met Val Asp Pro Gly Glu Glu Gln Pro Thr Gln Glu Asn Pro Lys Glu 
        515                 520                 525             


Asn Thr Leu Val Ser Lys Ser Pro Ser Ser Ser Ser Val Gly Gly Arg 
    530                 535                 540                 


Arg Asp Glu Leu Glu Glu Gly Ala Pro Ser Glu Ala Met Leu Arg Leu 
545                 550                 555                 560 


Leu Gln Ser Ala Phe Ser Lys Asn Ser Pro Pro Lys Gln Ser Pro Lys 
                565                 570                 575     


Lys Ser Pro Thr Ala Lys Leu Asn Ile Pro Tyr Glu Asn Phe Tyr Glu 
            580                 585                 590         


Ala Leu Glu Lys Leu Asn Lys Pro Ser Gln Leu Lys Asp Ser Glu Asp 
        595                 600                 605             


Ser Leu Tyr Asn Asp Tyr Val Asp Val Phe Tyr Asn Thr Lys Pro Tyr 
    610                 615                 620                 


Lys His Arg Asp Asp Arg Leu Leu Gln Ala Leu Val Asp Ile Leu Asn 
625                 630                 635                 640 


Glu Glu Asn 
            


<210>  2181
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  2181

Gln Asn Cys Ser Gly Pro Cys Arg Cys Pro Asp Glu Pro Ala Pro Arg 
1               5                   10                  15      


Cys Pro Ala Gly Val Ser Leu Val Leu Asp Gly Cys Gly Cys Cys Arg 
            20                  25                  30          


Val Cys Ala Lys Gln Leu Gly Glu Leu Cys Thr Glu Arg Asp Pro Cys 
        35                  40                  45              


Asp Pro His Lys Gly Leu Phe Cys Asp Phe Gly Ser Pro Ala Asn Arg 
    50                  55                  60                  


Lys Ile Gly Val Cys Thr Ala Lys Asp Gly Ala Pro Cys Ile Phe Gly 
65                  70                  75                  80  


Gly Thr Val Tyr Arg Ser Gly Glu Ser Phe Gln Ser Ser Cys Lys Tyr 
                85                  90                  95      


Gln Cys Thr Cys Leu Asp Gly Ala Val Gly Cys Met Pro Leu Cys Ser 
            100                 105                 110         


Met Asp Val Arg Leu Pro Ser Pro Asp Cys Pro Phe Pro Arg Arg Val 
        115                 120                 125             


Lys Leu Pro Gly Lys Cys Cys Glu Glu Trp Val Cys Asp Glu Pro Lys 
    130                 135                 140                 


Asp Gln Thr Val Val Gly Pro Ala Leu Ala Ala Tyr Arg Leu Glu Asp 
145                 150                 155                 160 


Thr Phe Gly Pro Asp Pro Thr Met Ile Arg Ala Asn Cys Leu Val Gln 
                165                 170                 175     


Thr Thr Glu Trp Ser Ala Cys Ser Lys Thr Cys Gly Met Gly Ile Ser 
            180                 185                 190         


Thr Arg Val Thr Asn Asp Asn Ala Ser Cys Arg Leu Glu Lys Gln Ser 
        195                 200                 205             


Arg Leu Cys Met Val Arg Pro Cys Glu Ala Asp Leu Glu Glu Asn Ile 
    210                 215                 220                 


Lys Lys Gly Lys Lys Cys Ile Arg Thr Pro Lys Ile Ser Lys Pro Ile 
225                 230                 235                 240 


Lys Phe Glu Leu Ser Gly Cys Thr Ser Met Lys Thr Tyr Arg Ala Lys 
                245                 250                 255     


Phe Cys Gly Val Cys Thr Asp Gly Arg Cys Cys Thr Pro His Arg Thr 
            260                 265                 270         


Thr Thr Leu Pro Val Glu Phe Lys Cys Pro Asp Gly Glu Val Met Lys 
        275                 280                 285             


Lys Asn Met Met Phe Ile Lys Thr Cys Ala Cys His Tyr Asn Cys Pro 
    290                 295                 300                 


Gly Asp Asn Asp Ile Phe Glu Ser Leu Tyr Tyr Arg Lys Met Tyr Gly 
305                 310                 315                 320 


Asp Met Ala 
            


<210>  2182
<211>  407
<212>  PRT
<213>  Homo Sapiens

<400>  2182

Gln Leu His Val Glu His Asp Gly Glu Ser Cys Ser Asn Ser Ser His 
1               5                   10                  15      


Gln Gln Ile Leu Glu Thr Gly Glu Gly Ser Pro Ser Leu Lys Ile Ala 
            20                  25                  30          


Pro Ala Asn Ala Asp Phe Ala Phe Arg Phe Tyr Tyr Leu Ile Ala Ser 
        35                  40                  45              


Glu Thr Pro Gly Lys Asn Ile Phe Phe Ser Pro Leu Ser Ile Ser Ala 
    50                  55                  60                  


Ala Tyr Ala Met Leu Ser Leu Gly Ala Cys Ser His Ser Arg Ser Gln 
65                  70                  75                  80  


Ile Leu Glu Gly Leu Gly Phe Asn Leu Thr Glu Leu Ser Glu Ser Asp 
                85                  90                  95      


Val His Arg Gly Phe Gln His Leu Leu His Thr Leu Asn Leu Pro Gly 
            100                 105                 110         


His Gly Leu Glu Thr Arg Val Gly Ser Ala Leu Phe Leu Ser His Asn 
        115                 120                 125             


Leu Lys Phe Leu Ala Lys Phe Leu Asn Asp Thr Met Ala Val Tyr Glu 
    130                 135                 140                 


Ala Lys Leu Phe His Thr Asn Phe Tyr Asp Thr Val Gly Thr Ile Gln 
145                 150                 155                 160 


Leu Ile Asn Asp His Val Lys Lys Glu Thr Arg Gly Lys Ile Val Asp 
                165                 170                 175     


Leu Val Ser Glu Leu Lys Lys Asp Val Leu Met Val Leu Val Asn Tyr 
            180                 185                 190         


Ile Tyr Phe Lys Ala Leu Trp Glu Lys Pro Phe Ile Ser Ser Arg Thr 
        195                 200                 205             


Thr Pro Lys Asp Phe Tyr Val Asp Glu Asn Thr Thr Val Arg Val Pro 
    210                 215                 220                 


Met Met Leu Gln Asp Gln Glu His His Trp Tyr Leu His Asp Arg Tyr 
225                 230                 235                 240 


Leu Pro Cys Ser Val Leu Arg Met Asp Tyr Lys Gly Asp Ala Thr Val 
                245                 250                 255     


Phe Phe Ile Leu Pro Asn Gln Gly Lys Met Arg Glu Ile Glu Glu Val 
            260                 265                 270         


Leu Thr Pro Glu Met Leu Met Arg Trp Asn Asn Leu Leu Arg Lys Arg 
        275                 280                 285             


Asn Phe Tyr Lys Lys Leu Glu Leu His Leu Pro Lys Phe Ser Ile Ser 
    290                 295                 300                 


Gly Ser Tyr Val Leu Asp Gln Ile Leu Pro Arg Leu Gly Phe Thr Asp 
305                 310                 315                 320 


Leu Phe Ser Lys Trp Ala Asp Leu Ser Gly Ile Thr Lys Gln Gln Lys 
                325                 330                 335     


Leu Glu Ala Ser Lys Ser Phe His Lys Ala Thr Leu Asp Val Asp Glu 
            340                 345                 350         


Ala Gly Thr Glu Ala Ala Ala Ala Thr Ser Phe Ala Ile Lys Phe Phe 
        355                 360                 365             


Ser Ala Gln Thr Asn Arg His Ile Leu Arg Phe Asn Arg Pro Phe Leu 
    370                 375                 380                 


Val Val Ile Phe Ser Thr Ser Thr Gln Ser Val Leu Phe Leu Gly Lys 
385                 390                 395                 400 


Val Val Asp Pro Thr Lys Pro 
                405         


<210>  2183
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  2183

Asn Ile Gly Ser Met Ile Ser Asn Met Asn Ala Ala Arg Ala Glu Phe 
1               5                   10                  15      


Gln Ala Arg Ile Asp Ala Ile Lys Gln Tyr Met His Phe Arg Asn Val 
            20                  25                  30          


Ser Lys Asp Met Glu Lys Arg Val Ile Lys Trp Phe Asp Tyr Leu Trp 
        35                  40                  45              


Thr Asn Lys Lys Thr Val Asp Glu Lys Glu Val Leu Lys Tyr Leu Pro 
    50                  55                  60                  


Asp Lys Leu Arg Ala Glu Ile Ala Ile Asn Val His Leu Asp Thr Leu 
65                  70                  75                  80  


Lys Lys Val Arg 
                


<210>  2184
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  2184

Leu His Thr Lys Gly Ala Leu Pro Leu Asp Thr Val Thr Phe Tyr Lys 
1               5                   10                  15      


Val Ile Pro Lys Ser Lys Phe Val Leu Val Lys Phe Asp Thr Gln Tyr 
            20                  25                  30          


Pro Tyr Gly Glu Lys Gln Asp Glu Phe Lys Arg Leu Ala Glu Asn Ser 
        35                  40                  45              


Ala Ser Ser Asp Asp Leu Leu Val Ala Glu Val Gly Ile Ser Asp Tyr 
    50                  55                  60                  


Gly Asp Lys Leu Asn Met Glu Leu Ser Glu Lys Tyr Lys Leu Asp Lys 
65                  70                  75                  80  


Glu Ser Tyr Pro Val Phe Tyr Leu Phe Arg Asp Gly Asp Phe Glu Asn 
                85                  90                  95      


Pro Val Pro Tyr Thr Gly Ala Val Lys Val Gly Ala Ile Gln Arg Trp 
            100                 105                 110         


Leu Lys Gly Gln Gly Val Tyr Leu Gly Met Pro Gly Cys Leu Pro Val 
        115                 120                 125             


Tyr Asp Ala Leu Ala Gly Glu Phe Ile Arg Ala Ser Gly Val Glu Ala 
    130                 135                 140                 


Arg Gln Ala Leu Leu Lys Gln Gly Gln Asp Asn Leu Ser Ser Val Lys 
145                 150                 155                 160 


Glu Thr Gln Lys Lys Trp Ala Glu Gln Tyr Leu Lys Ile Met Gly Lys 
                165                 170                 175     


Ile Leu Asp Gln Gly Glu Asp Phe Pro Ala Ser Glu Met Thr Arg Ile 
            180                 185                 190         


Ala Arg Leu Ile Glu Lys Asn Lys Met Ser Asp Gly Lys Lys Glu Glu 
        195                 200                 205             


Leu Gln Lys Ser Leu Asn Ile Leu Thr Ala Phe Gln Lys Lys Gly Ala 
    210                 215                 220                 


Glu Lys Glu Glu Leu 
225                 


<210>  2185
<211>  481
<212>  PRT
<213>  Homo Sapiens

<400>  2185

Ser Asp Val Leu Glu Leu Thr Asp Asp Asn Phe Glu Ser Arg Ile Ser 
1               5                   10                  15      


Asp Thr Gly Ser Ala Gly Leu Met Leu Val Glu Phe Phe Ala Pro Trp 
            20                  25                  30          


Cys Gly His Cys Lys Arg Leu Ala Pro Glu Tyr Glu Ala Ala Ala Thr 
        35                  40                  45              


Arg Leu Lys Gly Ile Val Pro Leu Ala Lys Val Asp Cys Thr Ala Asn 
    50                  55                  60                  


Thr Asn Thr Cys Asn Lys Tyr Gly Val Ser Gly Tyr Pro Thr Leu Lys 
65                  70                  75                  80  


Ile Phe Arg Asp Gly Glu Glu Ala Gly Ala Tyr Asp Gly Pro Arg Thr 
                85                  90                  95      


Ala Asp Gly Ile Val Ser His Leu Lys Lys Gln Ala Gly Pro Ala Ser 
            100                 105                 110         


Val Pro Leu Arg Thr Glu Glu Glu Phe Lys Lys Phe Ile Ser Asp Lys 
        115                 120                 125             


Asp Ala Ser Ile Val Gly Phe Phe Asp Asp Ser Phe Ser Glu Ala His 
    130                 135                 140                 


Ser Glu Phe Leu Lys Ala Ala Ser Asn Leu Arg Asp Asn Tyr Arg Phe 
145                 150                 155                 160 


Ala His Thr Asn Val Glu Ser Leu Val Asn Glu Tyr Asp Asp Asn Gly 
                165                 170                 175     


Glu Gly Ile Ile Leu Phe Arg Pro Ser His Leu Thr Asn Lys Phe Glu 
            180                 185                 190         


Asp Lys Thr Val Ala Tyr Thr Glu Gln Lys Met Thr Ser Gly Lys Ile 
        195                 200                 205             


Lys Lys Phe Ile Gln Glu Asn Ile Phe Gly Ile Cys Pro His Met Thr 
    210                 215                 220                 


Glu Asp Asn Lys Asp Leu Ile Gln Gly Lys Asp Leu Leu Ile Ala Tyr 
225                 230                 235                 240 


Tyr Asp Val Asp Tyr Glu Lys Asn Ala Lys Gly Ser Asn Tyr Trp Arg 
                245                 250                 255     


Asn Arg Val Met Met Val Ala Lys Lys Phe Leu Asp Ala Gly His Lys 
            260                 265                 270         


Leu Asn Phe Ala Val Ala Ser Arg Lys Thr Phe Ser His Glu Leu Ser 
        275                 280                 285             


Asp Phe Gly Leu Glu Ser Thr Ala Gly Glu Ile Pro Val Val Ala Ile 
    290                 295                 300                 


Arg Thr Ala Lys Gly Glu Lys Phe Val Met Gln Glu Glu Phe Ser Arg 
305                 310                 315                 320 


Asp Gly Lys Ala Leu Glu Arg Phe Leu Gln Asp Tyr Phe Asp Gly Asn 
                325                 330                 335     


Leu Lys Arg Tyr Leu Lys Ser Glu Pro Ile Pro Glu Ser Asn Asp Gly 
            340                 345                 350         


Pro Val Lys Val Val Val Ala Glu Asn Phe Asp Glu Ile Val Asn Asn 
        355                 360                 365             


Glu Asn Lys Asp Val Leu Ile Glu Phe Tyr Ala Pro Trp Cys Gly His 
    370                 375                 380                 


Cys Lys Asn Leu Glu Pro Lys Tyr Lys Glu Leu Gly Glu Lys Leu Ser 
385                 390                 395                 400 


Lys Asp Pro Asn Ile Val Ile Ala Lys Met Asp Ala Thr Ala Asn Asp 
                405                 410                 415     


Val Pro Ser Pro Tyr Glu Val Arg Gly Phe Pro Thr Ile Tyr Phe Ser 
            420                 425                 430         


Pro Ala Asn Lys Lys Leu Asn Pro Lys Lys Tyr Glu Gly Gly Arg Glu 
        435                 440                 445             


Leu Ser Asp Phe Ile Ser Tyr Leu Gln Arg Glu Ala Thr Asn Pro Pro 
    450                 455                 460                 


Val Ile Gln Glu Glu Lys Pro Lys Lys Lys Lys Lys Ala Gln Glu Asp 
465                 470                 475                 480 


Leu 
    


<210>  2186
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  2186

Ser Trp Ala Ile Tyr Tyr Leu Tyr Asn Ser Phe Thr Thr Thr Leu Pro 
1               5                   10                  15      


Trp Lys Gln Cys Asp Asn Pro Trp Asn Thr Asp Arg Cys Phe Ser Asn 
            20                  25                  30          


Tyr Ser Met Val Asn Thr Thr Asn Met Thr Ser Ala Val Val Glu Phe 
        35                  40                  45              


Trp Glu Arg Asn Met His Gln Met Thr Asp Gly Leu Asp Lys Pro Gly 
    50                  55                  60                  


Gln Ile Arg 
65          


<210>  2187
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  2187

Arg Cys Gly Leu Ala Gly Ala Ala Gly Gly Ala Gln Arg Gly Leu Ser 
1               5                   10                  15      


Glu Pro Ser Ser Ile Ala Lys His Glu Asp Ser Leu Leu Lys Asp Leu 
            20                  25                  30          


Phe Gln Asp Tyr Glu Arg Trp Val Arg Pro Val Glu His Leu Asn Asp 
        35                  40                  45              


Lys Ile Lys Ile Lys Phe Gly Leu Ala Ile Ser Gln Leu Val Asp Val 
    50                  55                  60                  


Asp Glu Lys Asn Gln Leu Met Thr Thr Asn Val Trp Leu Lys Gln Glu 
65                  70                  75                  80  


Trp Ile Asp Val Lys Leu Arg Trp Asn Pro Asp Asp Tyr Gly Gly Ile 
                85                  90                  95      


Lys Val Ile Arg Val Pro Ser Asp Ser Val Trp Thr Pro Asp Ile Val 
            100                 105                 110         


Leu Phe Asp Asn Ala Asp Gly Arg Phe Glu Gly Thr Ser Thr Lys Thr 
        115                 120                 125             


Val Ile Arg Tyr Asn Gly Thr Val Thr Trp Thr Pro Pro Ala Asn Tyr 
    130                 135                 140                 


Lys Ser Ser Cys Thr Ile Asp Val Thr Phe Phe Pro Phe Asp Leu Gln 
145                 150                 155                 160 


Asn Cys Ser Met Lys Phe Gly Ser Trp Thr Tyr Asp Gly Ser Gln Val 
                165                 170                 175     


Asp Ile Ile Leu Glu Asp Gln Asp Val Asp Lys Arg Asp Phe Phe Asp 
            180                 185                 190         


Asn Gly Glu Trp Glu Ile Val Ser Ala Thr Gly Ser Lys Gly Asn Arg 
        195                 200                 205             


Thr Asp Ser Cys Cys Trp Tyr Pro Tyr Val Thr Tyr Ser Phe Val Ile 
    210                 215                 220                 


Lys Arg Leu Pro Leu Phe Tyr Thr 
225                 230         


<210>  2188
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  2188

Tyr Ser Arg Glu Lys Asn Gln Pro Lys Pro Ser Pro Lys Arg Glu Ser 
1               5                   10                  15      


Gly Glu Glu Phe Arg Met Glu Lys Leu Asn Gln Leu Trp Glu Lys Ala 
            20                  25                  30          


Gln Arg Leu His Leu Pro Pro Val Arg Leu Ala Glu Leu His Ala Asp 
        35                  40                  45              


Leu Lys Ile Gln Glu Arg Asp Glu Leu Ala Trp Lys Lys Leu Lys Leu 
    50                  55                  60                  


Asp Gly Leu Asp Glu Asp Gly Glu Lys Glu Ala Arg Leu Ile Arg Asn 
65                  70                  75                  80  


Leu Asn Val Ile Leu Ala Lys Tyr Gly Leu Asp Gly Lys Lys Asp Ala 
                85                  90                  95      


Arg Gln Val Thr Ser Asn Ser Leu Ser Gly Thr Gln Glu Asp Gly Leu 
            100                 105                 110         


Asp Asp Pro Arg Leu Glu Lys Leu Trp His Lys Ala Lys Thr Ser Gly 
        115                 120                 125             


Lys Phe Ser Gly Glu Glu Leu Asp Lys Leu Trp Arg Glu Phe Leu His 
    130                 135                 140                 


His Lys Glu Lys Val His Glu Tyr Asn Val Leu Leu Glu Thr Leu Ser 
145                 150                 155                 160 


Arg Thr Glu Glu Ile His Glu Asn Val Ile Ser Pro Ser Asp Leu Ser 
                165                 170                 175     


Asp Ile Lys Gly Ser Val Leu His Ser Arg His Thr Glu Leu Lys Glu 
            180                 185                 190         


Lys Leu Arg Ser Ile Asn Gln Gly Leu Asp Arg Leu Arg Arg Val Ser 
        195                 200                 205             


His Gln Gly Tyr Ser Thr Glu Ala Glu Phe Glu Glu Pro Arg Val Ile 
    210                 215                 220                 


Asp Leu Trp Asp Leu Ala Gln Ser Ala Asn Leu Thr Asp Lys Glu Leu 
225                 230                 235                 240 


Glu Ala Phe Arg Glu Glu Leu Lys His Phe Glu Ala Lys Ile Glu Lys 
                245                 250                 255     


His Asn His Tyr Gln Lys Gln Leu Glu Ile Ala His Glu Lys Leu Arg 
            260                 265                 270         


His Ala Glu Ser Val Gly Asp Gly Glu Arg Val Ser Arg Ser Arg Glu 
        275                 280                 285             


Lys His Ala Leu Leu Glu Gly Arg Thr Lys Glu Leu Gly Tyr Thr Val 
    290                 295                 300                 


Lys Lys His Leu Gln Asp Leu Ser Gly Arg Ile Ser Arg Ala Arg His 
305                 310                 315                 320 


Asn Glu Leu 
            


<210>  2189
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  2189

Arg Val Ala Asn Ala Glu Glu Lys Leu Met Asp Asp Leu Leu Asn Lys 
1               5                   10                  15      


Thr Arg Tyr Asn Asn Leu Ile Arg Pro Ala Thr Ser Ser Ser Gln Leu 
            20                  25                  30          


Ile Ser Ile Lys Leu Gln Leu Ser Leu Ala Gln Leu Ile Ser Val Asn 
        35                  40                  45              


Glu Arg Glu Gln Ile Met Thr Thr Asn Val Trp Leu Lys Gln Glu Trp 
    50                  55                  60                  


Thr Asp Tyr Arg Leu Thr Trp Asn Ser Ser Arg Tyr Glu Gly Val Asn 
65                  70                  75                  80  


Ile Leu Arg Ile Pro Ala Lys Arg Ile Trp Leu Pro Asp Ile Val Leu 
                85                  90                  95      


Tyr Asn Asn Ala Asp Gly Thr Tyr Glu Val Ser Val Tyr Thr Asn Leu 
            100                 105                 110         


Ile Val Arg Ser Asn Gly Ser Val Leu Trp Leu Pro Pro Ala Ile Tyr 
        115                 120                 125             


Lys Ser Ala Cys Lys Ile Glu Val Lys Tyr Phe Pro Phe Asp Gln Gln 
    130                 135                 140                 


Asn Cys Thr Leu Lys Phe Arg Ser Trp Thr Tyr Asp His Thr Glu Ile 
145                 150                 155                 160 


Asp Met Val Leu Met Thr Pro Thr Ala Ser Met Asp Asp Phe Thr Pro 
                165                 170                 175     


Ser Gly Glu Trp Asp Ile Val Ala Leu Pro Gly Arg Arg Thr Val Asn 
            180                 185                 190         


Pro Gln Asp Pro Ser Tyr Val Asp Val Thr Tyr Asp Phe Ile Ile Lys 
        195                 200                 205             


Arg Lys Pro Leu Phe Tyr Thr 
    210                 215 


<210>  2190
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  2190

Ser Asp Ser Glu Glu Glu Met Lys Ala Leu Glu Ala Asp Phe Leu Thr 
1               5                   10                  15      


Asn Met His Thr Ser Lys Ile Ser Lys Ala His Val Pro Ser Trp Lys 
            20                  25                  30          


Met Thr Leu Leu Asn Val Cys Ser Leu Val Asn Asn Leu Asn Ser Pro 
        35                  40                  45              


Ala Glu Glu Thr Gly Glu Val His Glu Glu Glu Leu Val Ala Arg Arg 
    50                  55                  60                  


Lys Leu Pro Thr Ala Leu Asp Gly Phe Ser Leu Glu Ala Met Leu Thr 
65                  70                  75                  80  


Ile Tyr Gln Leu His Lys Ile Cys His Ser Arg Ala Phe Gln His Trp 
                85                  90                  95      


Glu Leu Ile Gln Glu Asp Ile Leu Asp Thr Gly Asn Asp Lys Asn Gly 
            100                 105                 110         


Lys Glu Glu Val Ile Lys Arg Lys Ile Pro Tyr Ile Leu 
        115                 120                 125 


<210>  2191
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  2191

Ser Asn Thr Gln Ala Glu Arg Ser Ile Ile Gly Met Ile Asp Met Phe 
1               5                   10                  15      


His Lys Tyr Thr Arg Arg Asp Asp Lys Ile Asp Lys Pro Ser Leu Leu 
            20                  25                  30          


Thr Met Met Lys Glu Asn Phe Pro Asn Phe Leu Ser Ala Cys Asp Lys 
        35                  40                  45              


Lys Gly Thr Asn Tyr Leu Ala Asp Val Phe Glu Lys Lys Asp Lys Asn 
    50                  55                  60                  


Glu Asp Lys Lys Ile Asp Phe Ser Glu Phe Leu Ser Leu Leu Gly Asp 
65                  70                  75                  80  


Ile Ala Thr Asp Tyr His Lys Gln Ser His Gly Ala Ala Pro Cys Ser 
                85                  90                  95      


Gly Gly Ser Gln 
            100 


<210>  2192
<211>  362
<212>  PRT
<213>  Homo Sapiens

<400>  2192

Gln Glu Gly Leu Asp Phe Pro Glu Tyr Asp Gly Val Asp Arg Val Ile 
1               5                   10                  15      


Asn Val Asn Ala Lys Asn Tyr Lys Asn Val Phe Lys Lys Tyr Glu Val 
            20                  25                  30          


Leu Ala Leu Leu Tyr His Glu Pro Pro Glu Asp Asp Lys Ala Ser Gln 
        35                  40                  45              


Arg Gln Phe Glu Met Glu Glu Leu Ile Leu Glu Leu Ala Ala Gln Val 
    50                  55                  60                  


Leu Glu Asp Lys Gly Val Gly Phe Gly Leu Val Asp Ser Glu Lys Asp 
65                  70                  75                  80  


Ala Ala Val Ala Lys Lys Leu Gly Leu Thr Glu Val Asp Ser Met Tyr 
                85                  90                  95      


Val Phe Lys Gly Asp Glu Val Ile Glu Tyr Asp Gly Glu Phe Ser Ala 
            100                 105                 110         


Asp Thr Ile Val Glu Phe Leu Leu Asp Val Leu Glu Asp Pro Val Glu 
        115                 120                 125             


Leu Ile Glu Gly Glu Arg Glu Leu Gln Ala Phe Glu Asn Ile Glu Asp 
    130                 135                 140                 


Glu Ile Lys Leu Ile Gly Tyr Phe Lys Ser Lys Asp Ser Glu His Tyr 
145                 150                 155                 160 


Lys Ala Phe Glu Asp Ala Ala Glu Glu Phe His Pro Tyr Ile Pro Phe 
                165                 170                 175     


Phe Ala Thr Phe Asp Ser Lys Val Ala Lys Lys Leu Thr Leu Lys Leu 
            180                 185                 190         


Asn Glu Ile Asp Phe Tyr Glu Ala Phe Met Glu Glu Pro Val Thr Ile 
        195                 200                 205             


Pro Asp Lys Pro Asn Ser Glu Glu Glu Ile Val Asn Phe Val Glu Glu 
    210                 215                 220                 


His Arg Arg Ser Thr Leu Arg Lys Leu Lys Pro Glu Ser Met Tyr Glu 
225                 230                 235                 240 


Thr Trp Glu Asp Asp Met Asp Gly Ile His Ile Val Ala Phe Ala Glu 
                245                 250                 255     


Glu Ala Asp Pro Asp Gly Phe Glu Phe Leu Glu Thr Leu Lys Ala Val 
            260                 265                 270         


Ala Gln Asp Asn Thr Glu Asn Pro Asp Leu Ser Ile Ile Trp Ile Asp 
        275                 280                 285             


Pro Asp Asp Phe Pro Leu Leu Val Pro Tyr Trp Glu Lys Thr Phe Asp 
    290                 295                 300                 


Ile Asp Leu Ser Ala Pro Gln Ile Gly Val Val Asn Val Thr Asp Ala 
305                 310                 315                 320 


Asp Ser Val Trp Met Glu Met Asp Asp Glu Glu Asp Leu Pro Ser Ala 
                325                 330                 335     


Glu Glu Leu Glu Asp Trp Leu Glu Asp Val Leu Glu Gly Glu Ile Asn 
            340                 345                 350         


Thr Glu Asp Asp Asp Asp Asp Asp Asp Asp 
        355                 360         


<210>  2193
<211>  228
<212>  PRT
<213>  Homo Sapiens

<400>  2193

Gln Met Pro Thr Ser Ser Val Lys Asp Glu Thr Asn Asp Asn Ile Thr 
1               5                   10                  15      


Ile Phe Thr Arg Ile Leu Asp Gly Leu Leu Asp Gly Tyr Asp Asn Arg 
            20                  25                  30          


Leu Arg Pro Gly Leu Gly Glu Arg Ile Thr Gln Val Arg Thr Asp Ile 
        35                  40                  45              


Tyr Val Thr Ser Phe Gly Pro Val Ser Asp Thr Glu Met Glu Tyr Thr 
    50                  55                  60                  


Ile Asp Val Phe Phe Arg Gln Ser Trp Lys Asp Glu Arg Leu Arg Phe 
65                  70                  75                  80  


Lys Gly Pro Met Gln Arg Leu Pro Leu Asn Asn Leu Leu Ala Ser Lys 
                85                  90                  95      


Ile Trp Thr Pro Asp Thr Phe Phe His Asn Gly Lys Lys Ser Ile Ala 
            100                 105                 110         


His Asn Met Thr Thr Pro Asn Lys Leu Leu Arg Leu Glu Asp Asp Gly 
        115                 120                 125             


Thr Leu Leu Tyr Thr Met Arg Leu Thr Ile Ser Ala Glu Cys Pro Met 
    130                 135                 140                 


Gln Leu Glu Asp Phe Pro Met Asp Ala His Ala Cys Pro Leu Lys Phe 
145                 150                 155                 160 


Gly Ser Tyr Ala Tyr Pro Asn Ser Glu Val Val Tyr Val Trp Thr Asn 
                165                 170                 175     


Gly Ser Thr Lys Ser Val Val Val Ala Glu Asp Gly Ser Arg Leu Asn 
            180                 185                 190         


Gln Tyr His Leu Met Gly Gln Thr Val Gly Thr Glu Asn Ile Ser Thr 
        195                 200                 205             


Ser Thr Gly Glu Tyr Thr Ile Met Thr Ala His Phe His Leu Lys Arg 
    210                 215                 220                 


Lys Ile Gly Tyr 
225             


<210>  2194
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2194

Met Glu Arg Ala Ser Leu Ile Gln Lys Ala Lys Leu Ala Glu Gln Ala 
1               5                   10                  15      


Glu Arg Tyr Glu Asp Met Ala Ala Phe Met Lys Gly Ala Val Glu Lys 
            20                  25                  30          


Gly Glu Glu Leu Ser Cys Glu Glu Arg Asn Leu Leu Ser Val Ala Tyr 
        35                  40                  45              


Lys Asn Val Val Gly Gly Gln Arg Ala Ala Trp Arg Val Leu Ser Ser 
    50                  55                  60                  


Ile Glu Gln Lys Ser Asn Glu Glu Gly Ser Glu Glu Lys Gly Pro Glu 
65                  70                  75                  80  


Val Arg Glu Tyr Arg Glu Lys Val Glu Thr Glu Leu Gln Gly Val Cys 
                85                  90                  95      


Asp Thr Val Leu Gly Leu Leu Asp Ser His Leu Ile Lys Glu Ala Gly 
            100                 105                 110         


Asp Ala Glu Ser Arg Val Phe Tyr Leu Lys Met Lys Gly Asp Tyr Tyr 
        115                 120                 125             


Arg Tyr Leu Ala Glu Val Ala Thr Gly Asp Asp Lys Lys Arg Ile Ile 
    130                 135                 140                 


Asp Ser Ala Arg Ser Ala Tyr Gln Glu Ala Met Asp Ile Ser Lys Lys 
145                 150                 155                 160 


Glu Met Pro Pro Thr Asn Pro Ile Arg Leu Gly Leu Ala Leu Asn Phe 
                165                 170                 175     


Ser Val Phe His Tyr Glu Ile Ala Asn Ser Pro Glu Glu Ala Ile Ser 
            180                 185                 190         


Leu Ala Lys Thr Thr Phe Asp Glu Ala Met Ala Asp Leu His Thr Leu 
        195                 200                 205             


Ser Glu Asp Ser Tyr Lys Asp Ser Thr Leu Ile Met Gln Leu Leu Arg 
    210                 215                 220                 


Asp Asn Leu Thr Leu Trp Thr Ala Asp Asn Ala Gly Glu Glu Gly Gly 
225                 230                 235                 240 


Glu Ala Pro Gln Glu Pro Gln Ser 
                245             


<210>  2195
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  2195

Ser Glu Ala Glu His Arg Leu Phe Glu Arg Leu Phe Glu Asp Tyr Asn 
1               5                   10                  15      


Glu Ile Ile Arg Pro Val Ala Asn Val Ser Asp Pro Val Ile Ile His 
            20                  25                  30          


Phe Glu Val Ser Met Ser Gln Leu Val Lys Val Asp Glu Val Asn Gln 
        35                  40                  45              


Ile Met Glu Thr Asn Leu Trp Leu Lys Gln Ile Trp Asn Asp Tyr Lys 
    50                  55                  60                  


Leu Lys Trp Asn Pro Ser Asp Tyr Gly Gly Ala Glu Phe Met Arg Val 
65                  70                  75                  80  


Pro Ala Gln Lys Ile Trp Lys Pro Asp Ile Val Leu Tyr Asn Asn Ala 
                85                  90                  95      


Val Gly Asp Phe Gln Val Asp Asp Lys Thr Lys Ala Leu Leu Lys Tyr 
            100                 105                 110         


Thr Gly Glu Val Thr Trp Ile Pro Pro Ala Ile Phe Lys Ser Ser Cys 
        115                 120                 125             


Lys Ile Asp Val Thr Tyr Phe Pro Phe Asp Tyr Gln Asn Cys Thr Met 
    130                 135                 140                 


Lys Phe Gly Ser Trp Ser Tyr Asp Lys Ala Lys Ile Asp Leu Val Leu 
145                 150                 155                 160 


Ile Gly Ser Ser Met Asn Leu Lys Asp Tyr Trp Glu Ser Gly Glu Trp 
                165                 170                 175     


Ala Ile Ile Lys Ala Pro Gly Tyr Lys His Asp Ile Lys Tyr Asn Cys 
            180                 185                 190         


Cys Glu Glu Ile Tyr Pro Asp Ile Thr Tyr Ser Leu Tyr Ile Arg Arg 
        195                 200                 205             


Leu 
    


<210>  2196
<211>  589
<212>  PRT
<213>  Homo Sapiens

<400>  2196

Met Ala Ser Glu Ile His Met Thr Gly Pro Met Cys Leu Ile Glu Asn 
1               5                   10                  15      


Thr Asn Gly Arg Leu Met Ala Asn Pro Glu Ala Leu Lys Ile Leu Ser 
            20                  25                  30          


Ala Ile Thr Gln Pro Met Val Val Val Ala Ile Val Gly Leu Tyr Arg 
        35                  40                  45              


Thr Gly Lys Ser Tyr Leu Met Asn Lys Leu Ala Gly Lys Lys Lys Gly 
    50                  55                  60                  


Phe Ser Leu Gly Ser Thr Val Gln Ser His Thr Lys Gly Ile Trp Met 
65                  70                  75                  80  


Trp Cys Val Pro His Pro Lys Lys Pro Gly His Ile Leu Val Leu Leu 
                85                  90                  95      


Asp Thr Glu Gly Leu Gly Asp Val Glu Lys Gly Asp Asn Gln Asn Asp 
            100                 105                 110         


Ser Trp Ile Phe Ala Leu Ala Val Leu Leu Ser Ser Thr Phe Val Tyr 
        115                 120                 125             


Asn Ser Ile Gly Thr Ile Asn Gln Gln Ala Met Asp Gln Leu Tyr Tyr 
    130                 135                 140                 


Val Thr Glu Leu Thr His Arg Ile Arg Ser Lys Ser Ser Pro Asp Glu 
145                 150                 155                 160 


Asn Glu Asn Glu Val Glu Asp Ser Ala Asp Phe Val Ser Phe Phe Pro 
                165                 170                 175     


Asp Phe Val Trp Thr Leu Arg Asp Phe Ser Leu Asp Leu Glu Ala Asp 
            180                 185                 190         


Gly Gln Pro Leu Thr Pro Asp Glu Tyr Leu Thr Tyr Ser Leu Lys Leu 
        195                 200                 205             


Lys Lys Gly Thr Ser Gln Lys Asp Glu Thr Phe Asn Leu Pro Arg Leu 
    210                 215                 220                 


Cys Ile Arg Lys Phe Phe Pro Lys Lys Lys Cys Phe Val Phe Asp Arg 
225                 230                 235                 240 


Pro Val His Arg Arg Lys Leu Ala Gln Leu Glu Lys Leu Gln Asp Glu 
                245                 250                 255     


Glu Leu Asp Pro Glu Phe Val Gln Gln Val Ala Asp Phe Cys Ser Tyr 
            260                 265                 270         


Ile Phe Ser Asn Ser Lys Thr Lys Thr Leu Ser Gly Gly Ile Gln Val 
        275                 280                 285             


Asn Gly Pro Arg Leu Glu Ser Leu Val Leu Thr Tyr Val Asn Ala Ile 
    290                 295                 300                 


Ser Ser Gly Asp Leu Pro Cys Met Glu Asn Ala Val Leu Ala Leu Ala 
305                 310                 315                 320 


Gln Ile Glu Asn Ser Ala Ala Val Gln Lys Ala Ile Ala His Tyr Glu 
                325                 330                 335     


Gln Gln Met Gly Gln Lys Val Gln Leu Pro Thr Glu Ser Leu Gln Glu 
            340                 345                 350         


Leu Leu Asp Leu His Arg Asp Ser Glu Arg Glu Ala Ile Glu Val Phe 
        355                 360                 365             


Ile Arg Ser Ser Phe Lys Asp Val Asp His Leu Phe Gln Lys Glu Leu 
    370                 375                 380                 


Ala Ala Gln Leu Glu Lys Lys Arg Asp Asp Phe Cys Lys Gln Asn Gln 
385                 390                 395                 400 


Glu Ala Ser Ser Asp Arg Cys Ser Gly Leu Leu Gln Val Ile Phe Ser 
                405                 410                 415     


Pro Leu Glu Glu Glu Val Lys Ala Gly Ile Tyr Ser Lys Pro Gly Gly 
            420                 425                 430         


Tyr Arg Leu Phe Val Gln Lys Leu Gln Asp Leu Lys Lys Lys Tyr Tyr 
        435                 440                 445             


Glu Glu Pro Arg Lys Gly Ile Gln Ala Glu Glu Ile Leu Gln Thr Tyr 
    450                 455                 460                 


Leu Lys Ser Lys Glu Ser Met Thr Asp Ala Ile Leu Gln Thr Asp Gln 
465                 470                 475                 480 


Thr Leu Thr Glu Lys Glu Lys Glu Ile Glu Val Glu Arg Val Lys Ala 
                485                 490                 495     


Glu Ser Ala Gln Ala Ser Ala Lys Met Leu Gln Glu Met Gln Arg Lys 
            500                 505                 510         


Asn Glu Gln Met Met Glu Gln Lys Glu Arg Ser Tyr Gln Glu His Leu 
        515                 520                 525             


Lys Gln Leu Thr Glu Lys Met Glu Asn Asp Arg Val Gln Leu Leu Lys 
    530                 535                 540                 


Glu Gln Glu Arg Thr Leu Ala Leu Lys Leu Gln Glu Gln Glu Gln Leu 
545                 550                 555                 560 


Leu Lys Glu Gly Phe Gln Lys Glu Ser Arg Ile Met Lys Asn Glu Ile 
                565                 570                 575     


Gln Asp Leu Gln Thr Lys Met Arg Arg Arg Lys Ala Cys 
            580                 585                 


<210>  2197
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  2197

Ala Pro Gln Pro Pro Asn Ile Leu Leu Leu Leu Met Asp Asp Met Gly 
1               5                   10                  15      


Trp Gly Asp Leu Gly Val Tyr Gly Glu Pro Ser Arg Glu Thr Pro Asn 
            20                  25                  30          


Leu Asp Arg Met Ala Ala Glu Gly Leu Leu Phe Pro Asn Phe Tyr Ser 
        35                  40                  45              


Ala Asn Pro Leu Cys Ser Pro Ser Arg Ala Ala Leu Leu Thr Gly Arg 
    50                  55                  60                  


Leu Pro Ile Arg Asn Gly Phe Tyr Thr Thr Asn Ala His Ala Arg Asn 
65                  70                  75                  80  


Ala Tyr Thr Pro Gln Glu Ile Val Gly Gly Ile Pro Asp Ser Glu Gln 
                85                  90                  95      


Leu Leu Pro Glu Leu Leu Lys Lys Ala Gly Tyr Val Ser Lys Ile Val 
            100                 105                 110         


Gly Lys Trp His Leu Gly His Arg Pro Gln Phe His Pro Leu Lys His 
        115                 120                 125             


Gly Phe Asp Glu Trp Phe Gly Ser Pro Asn Cys His Phe Gly Pro Tyr 
    130                 135                 140                 


Asp Asn Lys Ala Arg Pro Asn Ile Pro Val Tyr Arg Asp Trp Glu Met 
145                 150                 155                 160 


Val Gly Arg Tyr Tyr Glu Glu Phe Pro Ile Asn Leu Lys Thr Gly Glu 
                165                 170                 175     


Ala Asn Leu Thr Gln Ile Tyr Leu Gln Glu Ala Leu Asp Phe Ile Lys 
            180                 185                 190         


Arg Gln Ala Arg His His Pro Phe Phe Leu Tyr Trp Ala Val Asp Ala 
        195                 200                 205             


Thr His Ala Pro Val Tyr Ala Ser Lys Pro Phe Leu Gly Thr Ser Gln 
    210                 215                 220                 


Arg Gly Arg Tyr Gly Asp Ala Val Arg Glu Ile Asp Asp Ser Ile Gly 
225                 230                 235                 240 


Lys Ile Leu Glu Leu Leu Gln Asp Leu His Val Ala Asp Asn Thr Phe 
                245                 250                 255     


Val Phe Phe Thr Ser Asp Asn Gly Ala Ala Leu Ile Ser Ala Pro Glu 
            260                 265                 270         


Gln Gly Gly Ser Asn Gly Pro Phe Leu Cys Gly Lys Gln Thr Thr Phe 
        275                 280                 285             


Glu Gly Gly Met Arg Glu Pro Ala Leu Ala Trp Trp Pro Gly His Val 
    290                 295                 300                 


Thr Ala Gly Gln Val Ser His Gln Leu Gly Ser Ile Met Asp Leu Phe 
305                 310                 315                 320 


Thr Thr Ser Leu Ala Leu Ala Gly Leu Thr Pro Pro Ser Asp Arg Ala 
                325                 330                 335     


Ile Asp Gly Leu Asn Leu Leu Pro Thr Leu Leu Gln Gly Arg Leu Met 
            340                 345                 350         


Asp Arg Pro Ile Phe Tyr Tyr Arg Gly Asp Thr Leu Met Ala Ala Thr 
        355                 360                 365             


Leu Gly Gln His Lys Ala His Phe Trp Thr Trp Thr Asn Ser Trp Glu 
    370                 375                 380                 


Asn Phe Arg Gln Gly Ile Asp Phe Cys Pro Gly Gln Asn Val Ser Gly 
385                 390                 395                 400 


Val Thr Thr His Asn Leu Glu Asp His Thr Lys Leu Pro Leu Ile Phe 
                405                 410                 415     


His Leu Gly Arg Asp Pro Gly Glu Arg Phe Pro Leu Ser Phe Ala Ser 
            420                 425                 430         


Ala Glu Tyr Gln Glu Ala Leu Ser Arg Ile Thr Ser Val Val Gln Gln 
        435                 440                 445             


His Gln Glu Ala Leu Val Pro Ala Gln Pro Gln Leu Asn Val Cys Asn 
    450                 455                 460                 


Trp Ala Val Met Asn Trp Ala Pro Pro Gly Cys Glu Lys Leu Gly Lys 
465                 470                 475                 480 


Cys Leu Thr Pro Pro Glu Ser Ile Pro Lys Lys Cys Leu Trp Ser His 
                485                 490                 495     


<210>  2198
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  2198

Gln Asp Gly Met Tyr Gln Arg Phe Leu Arg Gln His Val His Pro Glu 
1               5                   10                  15      


Glu Thr Gly Gly Ser Asp Arg Tyr Cys Asn Leu Met Met Gln Arg Arg 
            20                  25                  30          


Lys Met Thr Leu Tyr His Cys Lys Arg Phe Asn Thr Phe Ile His Glu 
        35                  40                  45              


Asp Ile Trp Asn Ile Arg Ser Ile Cys Ser Thr Thr Asn Ile Gln Cys 
    50                  55                  60                  


Lys Asn Gly Lys Met Asn Cys His Glu Gly Val Val Lys Val Thr Asp 
65                  70                  75                  80  


Cys Arg Asp Thr Gly Ser Ser Arg Ala Pro Asn Cys Arg Tyr Arg Ala 
                85                  90                  95      


Ile Ala Ser Thr Arg Arg Val Val Ile Ala Cys Glu Gly Asn Pro Gln 
            100                 105                 110         


Val Pro Val His Phe Asp Gly 
        115                 


<210>  2199
<211>  298
<212>  PRT
<213>  Homo Sapiens

<400>  2199

Asn Asp Cys Pro His Lys Lys Ser Ala Thr Leu Leu Pro Ser Phe Thr 
1               5                   10                  15      


Val Thr Pro Thr Val Thr Glu Ser Thr Gly Thr Thr Ser His Arg Thr 
            20                  25                  30          


Thr Lys Ser His Lys Thr Thr Thr His Arg Thr Thr Thr Thr Gly Thr 
        35                  40                  45              


Thr Ser His Gly Pro Thr Thr Ala Thr His Asn Pro Thr Thr Thr Ser 
    50                  55                  60                  


His Gly Asn Val Thr Val His Pro Thr Ser Asn Ser Thr Ala Thr Ser 
65                  70                  75                  80  


Gln Gly Pro Ser Thr Ala Thr His Ser Pro Ala Thr Thr Ser His Gly 
                85                  90                  95      


Asn Ala Thr Val His Pro Thr Ser Asn Ser Thr Ala Thr Ser Pro Gly 
            100                 105                 110         


Phe Thr Ser Ser Ala His Pro Glu Pro Pro Pro Pro Ser Pro Ser Pro 
        115                 120                 125             


Ser Pro Thr Ser Lys Glu Thr Ile Gly Asp Tyr Thr Trp Thr Asn Gly 
    130                 135                 140                 


Ser Gln Pro Cys Val His Leu Gln Ala Gln Ile Gln Ile Arg Val Met 
145                 150                 155                 160 


Tyr Thr Thr Gln Gly Gly Gly Glu Ala Trp Gly Ile Ser Val Leu Asn 
                165                 170                 175     


Pro Asn Lys Thr Lys Val Gln Gly Ser Cys Glu Gly Ala His Pro His 
            180                 185                 190         


Leu Leu Leu Ser Phe Pro Tyr Gly His Leu Ser Phe Gly Phe Met Gln 
        195                 200                 205             


Asp Leu Gln Gln Lys Val Val Tyr Leu Ser Tyr Met Ala Val Glu Tyr 
    210                 215                 220                 


Asn Val Ser Phe Pro His Ala Ala Gln Trp Thr Phe Ser Ala Gln Asn 
225                 230                 235                 240 


Ala Ser Leu Arg Asp Leu Gln Ala Pro Leu Gly Gln Ser Phe Ser Cys 
                245                 250                 255     


Ser Asn Ser Ser Ile Ile Leu Ser Pro Ala Val His Leu Asp Leu Leu 
            260                 265                 270         


Ser Leu Arg Leu Gln Ala Ala Gln Leu Pro His Thr Gly Val Phe Gly 
        275                 280                 285             


Gln Ser Phe Ser Cys Pro Ser Asp Arg Ser 
    290                 295             


<210>  2200
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2200

Gln Gly Glu Ser Arg Arg Gln Glu Pro Gly Asp Phe Val Lys Gln Asp 
1               5                   10                  15      


Ile Gly Gly Leu Ser Pro Lys His Ala Pro Asp Ile Pro Asp Asp Ser 
            20                  25                  30          


Thr Asp Asn Ile Thr Ile Phe Thr Arg Ile Leu Asp Arg Leu Leu Asp 
        35                  40                  45              


Gly Tyr Asp Asn Arg Leu Arg Pro Gly Leu Gly Asp Ala Val Thr Glu 
    50                  55                  60                  


Val Lys Thr Asp Ile Tyr Val Thr Ser Phe Gly Pro Val Ser Asp Thr 
65                  70                  75                  80  


Asp Met Glu Tyr Thr Ile Asp Val Phe Phe Arg Gln Thr Trp His Asp 
                85                  90                  95      


Glu Arg Leu Lys Phe Asp Gly Pro Met Lys Ile Leu Pro Leu Asn Asn 
            100                 105                 110         


Leu Leu Ala Ser Lys Ile Trp Thr Pro Asp Thr Phe Phe His Asn Gly 
        115                 120                 125             


Lys Lys Ser Val Ala His Asn Met Thr Thr Pro Asn Lys Leu Leu Arg 
    130                 135                 140                 


Leu Val Asp Asn Gly Thr Leu Pro Tyr Thr Met Arg Leu Thr Ile His 
145                 150                 155                 160 


Ala Glu Cys Pro Met His Leu Glu Asp Phe Pro Met Asp Val His Ala 
                165                 170                 175     


Cys Pro Leu Lys Phe Gly Ser Tyr Ala Tyr Thr Thr Ala Glu Val Val 
            180                 185                 190         


Tyr Ser Trp Thr Leu Gly Lys Asn Lys Ser Val Glu Val Ala Gln Asp 
        195                 200                 205             


Gly Ser Arg Leu Asn Gln Tyr Asp Leu Leu Gly His Val Val Gly Thr 
    210                 215                 220                 


Glu Ile Ile Arg Ser Ser Thr Gly Glu Tyr Val Val Met Thr Thr His 
225                 230                 235                 240 


Phe His Leu Lys Arg Lys Ile Gly 
                245             


<210>  2201
<211>  181
<212>  PRT
<213>  Homo Sapiens

<400>  2201

Lys Thr Glu Thr Ile Thr Thr Glu Lys Gln Ser Gln Pro Thr Leu Phe 
1               5                   10                  15      


Thr Ser Ser Met Ser Gln Val Leu Ala Asn Ser Gln Asn Thr Thr Gly 
            20                  25                  30          


Asn Pro Leu Gly Gln Pro Thr Gln Phe Ser Asp Thr Phe Ser Gly Gln 
        35                  40                  45              


Ser Ile Ser Pro Ala Lys Val Thr Ala Gly Gln Pro Thr Pro Ala Val 
    50                  55                  60                  


Tyr Thr Ser Ser Glu Lys Pro Glu Ala His Thr Ser Ala Gly Gln Pro 
65                  70                  75                  80  


Leu Ala Tyr Asn Thr Lys Gln Pro Thr Pro Ile Ala Asn Thr Ser Ser 
                85                  90                  95      


Gln Gln Ala Val Phe Thr Ser Ala Arg Gln Leu Pro Ser Ala Arg Thr 
            100                 105                 110         


Ser Thr Thr Gln Pro Pro Lys Ser Phe Val Tyr Thr Phe Thr Gln Gln 
        115                 120                 125             


Ser Ser Ser Val Gln Ile Pro Ser Arg Lys Gln Ile Thr Val His Asn 
    130                 135                 140                 


Pro Ser Thr Gln Pro Thr Ser Thr Val Lys Asn Ser Pro Arg Ser Thr 
145                 150                 155                 160 


Pro Gly Phe Ile Leu Asp Thr Thr Ser Asn Lys Gln Thr Pro Gln Lys 
                165                 170                 175     


Asn Asn Tyr Asn Ser 
            180     


<210>  2202
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  2202

Pro Pro Pro Leu Leu Leu Leu Leu Ala Leu Leu Pro Leu Leu Pro Ala 
1               5                   10                  15      


Pro Gly Ala Ala Ala Ala Pro Ala Pro Arg Pro Pro Glu Leu Gln Ser 
            20                  25                  30          


Ala Ser Ala Gly Pro Ser Val Ser Leu Tyr Leu Ser Glu Asp Glu Val 
        35                  40                  45              


Arg Arg Leu Ile Gly Leu Asp Ala Glu Leu Tyr Tyr Val Arg Asn Asp 
    50                  55                  60                  


Leu Ile Ser His Tyr Ala Leu Ser Phe Ser Leu Leu Val Pro Ser Glu 
65                  70                  75                  80  


Thr Asn Phe Leu His Phe Thr Trp His Ala Lys Ser Lys Val Glu Tyr 
                85                  90                  95      


Lys Leu Gly Phe Gln Val Asp Asn Val Leu Ala Met Asp Met Pro Gln 
            100                 105                 110         


Val Asn Ile Ser Val Gln Gly Glu Val Pro Arg Thr Leu Ser Val Phe 
        115                 120                 125             


Arg Val Glu Leu Ser Cys Thr Gly Lys Val Asp Ser Glu Val Met Ile 
    130                 135                 140                 


Leu Met Gln Leu Asn Leu Thr Val Asn Ser Ser Lys Asn Phe Thr Val 
145                 150                 155                 160 


Leu Asn Phe Lys Arg Arg Lys Met Cys Tyr Lys Lys Leu Glu Glu Val 
                165                 170                 175     


Lys Thr Ser Ala Leu Asp Lys Asn Thr Ser Arg Thr Ile Tyr Asp Pro 
            180                 185                 190         


Val His Ala Ala Pro Thr Thr Ser Thr Arg 
        195                 200         


<210>  2203
<211>  507
<212>  PRT
<213>  Homo Sapiens

<400>  2203

Asp Pro Ala Ser Lys Ser Arg Ser Cys Gly Glu Val Arg Gln Ile Tyr 
1               5                   10                  15      


Gly Ala Lys Gly Phe Ser Leu Ser Asp Val Pro Gln Ala Glu Ile Ser 
            20                  25                  30          


Gly Glu His Leu Arg Ile Cys Pro Gln Gly Tyr Thr Cys Cys Thr Ser 
        35                  40                  45              


Glu Met Glu Glu Asn Leu Ala Asn Arg Ser His Ala Glu Leu Glu Thr 
    50                  55                  60                  


Ala Leu Arg Asp Ser Ser Arg Val Leu Gln Ala Met Leu Ala Thr Gln 
65                  70                  75                  80  


Leu Arg Ser Phe Asp Asp His Phe Gln His Leu Leu Asn Asp Ser Glu 
                85                  90                  95      


Arg Thr Leu Gln Ala Thr Phe Pro Gly Ala Phe Gly Glu Leu Tyr Thr 
            100                 105                 110         


Gln Asn Ala Arg Ala Phe Arg Asp Leu Tyr Ser Glu Leu Arg Leu Tyr 
        115                 120                 125             


Tyr Arg Gly Ala Asn Leu His Leu Glu Glu Thr Leu Ala Glu Phe Trp 
    130                 135                 140                 


Ala Arg Leu Leu Glu Arg Leu Phe Lys Gln Leu His Pro Gln Leu Leu 
145                 150                 155                 160 


Leu Pro Asp Asp Tyr Leu Asp Cys Leu Gly Lys Gln Ala Glu Ala Leu 
                165                 170                 175     


Arg Pro Phe Gly Glu Ala Pro Arg Glu Leu Arg Leu Arg Ala Thr Arg 
            180                 185                 190         


Ala Phe Val Ala Ala Arg Ser Phe Val Gln Gly Leu Gly Val Ala Ser 
        195                 200                 205             


Asp Val Val Arg Lys Val Ala Gln Val Pro Leu Gly Pro Glu Cys Ser 
    210                 215                 220                 


Arg Ala Val Met Lys Leu Val Tyr Cys Ala His Cys Leu Gly Val Pro 
225                 230                 235                 240 


Gly Ala Arg Pro Cys Pro Asp Tyr Cys Arg Asn Val Leu Lys Gly Cys 
                245                 250                 255     


Leu Ala Asn Gln Ala Asp Leu Asp Ala Glu Trp Arg Asn Leu Leu Asp 
            260                 265                 270         


Ser Met Val Leu Ile Thr Asp Lys Phe Trp Gly Thr Ser Gly Val Glu 
        275                 280                 285             


Ser Val Ile Gly Ser Val His Thr Trp Leu Ala Glu Ala Ile Asn Ala 
    290                 295                 300                 


Leu Gln Asp Asn Arg Asp Thr Leu Thr Ala Lys Val Ile Gln Gly Cys 
305                 310                 315                 320 


Gly Asn Pro Lys Val Asn Pro Gln Gly Pro Gly Pro Glu Glu Lys Arg 
                325                 330                 335     


Arg Arg Gly Lys Leu Ala Pro Arg Glu Arg Pro Pro Ser Gly Thr Leu 
            340                 345                 350         


Glu Lys Leu Val Ser Glu Ala Lys Ala Gln Leu Arg Asp Val Gln Asp 
        355                 360                 365             


Phe Trp Ile Ser Leu Pro Gly Thr Leu Cys Ser Glu Lys Met Ala Leu 
    370                 375                 380                 


Ser Thr Ala Ser Asp Asp Arg Cys Trp Asn Gly Met Ala Arg Gly Arg 
385                 390                 395                 400 


Tyr Leu Pro Glu Val Met Gly Asp Gly Leu Ala Asn Gln Ile Asn Asn 
                405                 410                 415     


Pro Glu Val Glu Val Asp Ile Thr Lys Pro Asp Met Thr Ile Arg Gln 
            420                 425                 430         


Gln Ile Met Gln Leu Lys Ile Met Thr Asn Arg Leu Arg Ser Ala Tyr 
        435                 440                 445             


Asn Gly Asn Asp Val Asp Phe Gln Asp Ala Ser Asp Asp Gly Ser Gly 
    450                 455                 460                 


Ser Gly Ser Gly Asp Gly Cys Leu Asp Asp Leu Cys Gly Arg Lys Val 
465                 470                 475                 480 


Ser Arg Lys Ser Ser Ser Ser Arg Thr Pro Leu Thr His Ala Leu Pro 
                485                 490                 495     


Gly Leu Ser Glu Gln Glu Gly Gln Lys Thr Ser 
            500                 505         


<210>  2204
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  2204

Gly Lys Val Leu Val Val Pro Thr Asp Gly Ser His Trp Leu Ser Met 
1               5                   10                  15      


Arg Glu Ala Leu Arg Asp Leu His Ala Arg Gly His Gln Val Val Val 
            20                  25                  30          


Leu Thr Leu Glu Val Asn Met Tyr Ile Lys Glu Glu Asn Phe Phe Thr 
        35                  40                  45              


Leu Thr Thr Tyr Ala Ile Ser Trp Thr Gln Asp Glu Phe Asp Arg Leu 
    50                  55                  60                  


Leu Leu Gly His Thr Gln Ser Phe Phe Glu Thr Glu His Leu Leu Met 
65                  70                  75                  80  


Lys Phe Ser Arg Arg Met Ala Ile Met Asn Asn Met Ser Leu Ile Ile 
                85                  90                  95      


His Arg Ser Cys Val Glu Leu Leu His Asn Glu Ala Leu Ile Arg His 
            100                 105                 110         


Leu His Ala Thr Ser Phe Asp Val Val Leu Thr Asp Pro Phe His Leu 
        115                 120                 125             


Cys Ala Ala Val Leu Ala Lys Tyr Leu Ser Ile Pro Ala Val Phe Phe 
    130                 135                 140                 


Leu Arg Asn Ile Pro Cys Asp Leu Asp Phe Lys Gly Thr Gln Cys Pro 
145                 150                 155                 160 


Asn Pro Ser Ser Tyr Ile Pro Arg Leu Leu Thr Thr Asn Ser Asp His 
                165                 170                 175     


Met Thr Phe Leu Gln Arg Val Lys Asn Met Leu Tyr Pro Leu Ala Leu 
            180                 185                 190         


Ser Tyr Leu Cys His Ala Val Ser Ala Pro Tyr Ala Ser Leu Ala Ser 
        195                 200                 205             


Glu Leu Phe Gln Arg Glu Val Ser Val Val Asp Leu Val Ser His Ala 
    210                 215                 220                 


Ser Val Trp Leu Phe Arg Gly Asp Phe Val Met Asp Tyr Pro Arg Pro 
225                 230                 235                 240 


Ile Met Pro Asn Met Val Phe Ile Gly Gly Ile Asn Cys Ala Asn Gly 
                245                 250                 255     


Lys Pro Leu Ser Gln Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu 
            260                 265                 270         


His Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro 
        275                 280                 285             


Glu Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile Pro Gln 
    290                 295                 300                 


Thr Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn 
305                 310                 315                 320 


Asn Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His 
                325                 330                 335     


Pro Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr 
            340                 345                 350         


Glu Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly 
        355                 360                 365             


Asp Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val 
    370                 375                 380                 


Thr Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu 
385                 390                 395                 400 


Lys Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu 
                405                 410                 415     


Ser Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val 
            420                 425                 430         


Phe Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg 
        435                 440                 445             


Pro Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460             


<210>  2205
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  2205

Glu Ser Trp Arg Ser Phe Phe Lys Glu Ala Leu Gln Gly Val Gly Asp 
1               5                   10                  15      


Met Gly Arg Ala Tyr Trp Asp Ile Met Ile Ser Asn His Gln Asn Ser 
            20                  25                  30          


Asn Arg Tyr Leu Tyr Ala Arg Gly Asn Tyr Asp Ala Ala Gln Arg Gly 
        35                  40                  45              


Pro Gly Gly Val Trp Ala Ala Lys Leu Ile Ser Arg Ser Arg Val Tyr 
    50                  55                  60                  


Leu Gln Gly Leu Ile Asp Tyr Tyr Leu Phe Gly Asn Ser Ser Thr Val 
65                  70                  75                  80  


Leu Glu Asp Ser Lys Ser Asn Glu Lys Ala Glu Glu Trp Gly Arg Ser 
                85                  90                  95      


Gly Lys Asp Pro Asp Arg Phe Arg Pro Asp Gly Leu Pro Lys Lys Tyr 
            100                 105                 110         


<210>  2206
<211>  188
<212>  PRT
<213>  Homo Sapiens

<400>  2206

Cys Thr Cys Ser Pro Ser His Pro Gln Asp Ala Phe Cys Asn Ser Asp 
1               5                   10                  15      


Ile Val Ile Arg Ala Lys Val Val Gly Lys Lys Leu Val Lys Glu Gly 
            20                  25                  30          


Pro Phe Gly Thr Leu Val Tyr Thr Ile Lys Gln Met Lys Met Tyr Arg 
        35                  40                  45              


Gly Phe Thr Lys Met Pro His Val Gln Tyr Ile His Thr Glu Ala Ser 
    50                  55                  60                  


Glu Ser Leu Cys Gly Leu Lys Leu Glu Val Asn Lys Tyr Gln Tyr Leu 
65                  70                  75                  80  


Leu Thr Gly Arg Val Tyr Asp Gly Lys Met Tyr Thr Gly Leu Cys Asn 
                85                  90                  95      


Phe Val Glu Arg Trp Asp Gln Leu Thr Leu Ser Gln Arg Lys Gly Leu 
            100                 105                 110         


Asn Tyr Arg Tyr His Leu Gly Cys Asn Cys Lys Ile Lys Ser Cys Tyr 
        115                 120                 125             


Tyr Leu Pro Cys Phe Val Thr Ser Lys Asn Glu Cys Leu Trp Thr Asp 
    130                 135                 140                 


Met Leu Ser Asn Phe Gly Tyr Pro Gly Tyr Gln Ser Lys His Tyr Ala 
145                 150                 155                 160 


Cys Ile Arg Gln Lys Gly Gly Tyr Cys Ser Trp Tyr Arg Gly Trp Ala 
                165                 170                 175     


Pro Pro Asp Lys Ser Ile Ile Asn Ala Thr Asp Pro 
            180                 185             


<210>  2207
<211>  362
<212>  PRT
<213>  Homo Sapiens

<400>  2207

Tyr Lys Leu Val Cys Tyr Tyr Thr Ser Trp Ser Gln Tyr Arg Glu Gly 
1               5                   10                  15      


Asp Gly Ser Cys Phe Pro Asp Ala Leu Asp Arg Phe Leu Cys Thr His 
            20                  25                  30          


Ile Ile Tyr Ser Phe Ala Asn Ile Ser Asn Asp His Ile Asp Thr Trp 
        35                  40                  45              


Glu Trp Asn Asp Val Thr Leu Tyr Gly Met Leu Asn Thr Leu Lys Asn 
    50                  55                  60                  


Arg Asn Pro Asn Leu Lys Thr Leu Leu Ser Val Gly Gly Trp Asn Phe 
65                  70                  75                  80  


Gly Ser Gln Arg Phe Ser Lys Ile Ala Ser Asn Thr Gln Ser Arg Arg 
                85                  90                  95      


Thr Phe Ile Lys Ser Val Pro Pro Phe Leu Arg Thr His Gly Phe Asp 
            100                 105                 110         


Gly Leu Asp Leu Ala Trp Leu Tyr Pro Gly Arg Arg Asp Lys Gln His 
        115                 120                 125             


Phe Thr Thr Leu Ile Lys Glu Met Lys Ala Glu Phe Ile Lys Glu Ala 
    130                 135                 140                 


Gln Pro Gly Lys Lys Gln Leu Leu Leu Ser Ala Ala Leu Ser Ala Gly 
145                 150                 155                 160 


Lys Val Thr Ile Asp Ser Ser Tyr Asp Ile Ala Lys Ile Ser Gln His 
                165                 170                 175     


Leu Asp Phe Ile Ser Ile Met Thr Tyr Asp Phe His Gly Ala Trp Arg 
            180                 185                 190         


Gly Thr Thr Gly His His Ser Pro Leu Phe Arg Gly Gln Glu Asp Ala 
        195                 200                 205             


Ser Pro Asp Arg Phe Ser Asn Thr Asp Tyr Ala Val Gly Tyr Met Leu 
    210                 215                 220                 


Arg Leu Gly Ala Pro Ala Ser Lys Leu Val Met Gly Ile Pro Thr Phe 
225                 230                 235                 240 


Gly Arg Ser Phe Thr Leu Ala Ser Ser Glu Thr Gly Val Gly Ala Pro 
                245                 250                 255     


Ile Ser Gly Pro Gly Ile Pro Gly Arg Phe Thr Lys Glu Ala Gly Thr 
            260                 265                 270         


Leu Ala Tyr Tyr Glu Ile Cys Asp Phe Leu Arg Gly Ala Thr Val His 
        275                 280                 285             


Arg Ile Leu Gly Gln Gln Val Pro Tyr Ala Thr Lys Gly Asn Gln Trp 
    290                 295                 300                 


Val Gly Tyr Asp Asp Gln Glu Ser Val Lys Ser Lys Val Gln Tyr Leu 
305                 310                 315                 320 


Lys Asp Arg Gln Leu Ala Gly Ala Met Val Trp Ala Leu Asp Leu Asp 
                325                 330                 335     


Asp Phe Gln Gly Ser Phe Cys Gly Gln Asp Leu Arg Phe Pro Leu Thr 
            340                 345                 350         


Asn Ala Ile Lys Asp Ala Leu Ala Ala Thr 
        355                 360         


<210>  2208
<211>  558
<212>  PRT
<213>  Homo Sapiens

<400>  2208

Ser Arg His Gln Ala Pro Cys Gly Pro Gln Ala Phe Ala His Ala Ala 
1               5                   10                  15      


Val Ala Ala Asp Ser Lys Val Cys Ser Asp Ile Gly Arg Ala Ile Leu 
            20                  25                  30          


Gln Gln Gln Gly Ser Pro Val Asp Ala Thr Ile Ala Ala Leu Val Cys 
        35                  40                  45              


Thr Ser Val Val Asn Pro Gln Ser Met Gly Leu Gly Gly Gly Val Ile 
    50                  55                  60                  


Phe Thr Ile Tyr Asn Val Thr Thr Gly Lys Val Glu Val Ile Asn Ala 
65                  70                  75                  80  


Arg Glu Thr Val Pro Ala Ser His Ala Pro Ser Leu Leu Asp Gln Cys 
                85                  90                  95      


Ala Gln Ala Leu Pro Leu Gly Thr Gly Ala Gln Trp Ile Gly Val Pro 
            100                 105                 110         


Gly Glu Leu Arg Gly Tyr Ala Glu Ala His Arg Arg His Gly Arg Leu 
        115                 120                 125             


Pro Trp Ala Gln Leu Phe Gln Pro Thr Ile Ala Leu Leu Arg Gly Gly 
    130                 135                 140                 


His Val Val Ala Pro Val Leu Ser Arg Phe Leu His Asn Ser Ile Leu 
145                 150                 155                 160 


Arg Pro Ser Leu Gln Ala Ser Thr Leu Arg Gln Leu Phe Phe Asn Gly 
                165                 170                 175     


Thr Glu Pro Leu Arg Pro Gln Asp Pro Leu Pro Trp Pro Ala Leu Ala 
            180                 185                 190         


Thr Thr Leu Glu Thr Val Ala Thr Glu Gly Val Glu Val Phe Tyr Thr 
        195                 200                 205             


Gly Arg Leu Gly Gln Met Leu Val Glu Asp Ile Ala Lys Glu Gly Ser 
    210                 215                 220                 


Gln Leu Thr Leu Gln Asp Leu Ala Lys Phe Gln Pro Glu Val Val Asp 
225                 230                 235                 240 


Ala Leu Glu Val Pro Leu Gly Asp Tyr Thr Leu Tyr Ser Pro Pro Pro 
                245                 250                 255     


Pro Ala Gly Gly Ala Ile Leu Ser Phe Ile Leu Asn Val Leu Arg Gly 
            260                 265                 270         


Phe Asn Phe Ser Thr Glu Ser Met Ala Arg Pro Glu Gly Arg Val Asn 
        275                 280                 285             


Val Tyr His His Leu Val Glu Thr Leu Lys Phe Ala Lys Gly Gln Arg 
    290                 295                 300                 


Trp Arg Leu Gly Asp Pro Arg Ser His Pro Lys Leu Gln Asn Ala Ser 
305                 310                 315                 320 


Arg Asp Leu Leu Gly Glu Thr Leu Ala Gln Leu Ile Arg Gln Gln Ile 
                325                 330                 335     


Asp Gly Arg Gly Asp His Gln Leu Ser His Tyr Ser Leu Ala Glu Ala 
            340                 345                 350         


Trp Gly His Gly Thr Gly Thr Ser His Val Ser Val Leu Gly Glu Asp 
        355                 360                 365             


Gly Ser Ala Val Ala Ala Thr Ser Thr Ile Asn Thr Pro Phe Gly Ala 
    370                 375                 380                 


Met Val Tyr Ser Pro Arg Thr Gly Ile Ile Leu Asn Asn Glu Leu Leu 
385                 390                 395                 400 


Asp Leu Cys Glu Arg Cys Pro Arg Gly Ser Gly Thr Thr Pro Ser Pro 
                405                 410                 415     


Ala Val Ser Gly Asp Arg Val Gly Gly Ala Pro Gly Arg Cys Trp Pro 
            420                 425                 430         


Pro Val Pro Gly Glu Arg Ser Pro Ser Ser Met Val Pro Ser Ile Leu 
        435                 440                 445             


Ile Asn Lys Ala Gln Gly Ser Lys Leu Val Ile Gly Gly Ala Gly Gly 
    450                 455                 460                 


Glu Leu Ile Ile Ser Ala Val Ala Gln Ala Ile Met Ser Lys Leu Trp 
465                 470                 475                 480 


Leu Gly Phe Asp Leu Arg Ala Ala Ile Ala Ala Pro Ile Leu His Val 
                485                 490                 495     


Asn Ser Lys Gly Cys Val Glu Tyr Glu Pro Asn Phe Ser Gln Glu Val 
            500                 505                 510         


Gln Arg Gly Leu Gln Asp Arg Gly Gln Asn Gln Thr Gln Arg Pro Phe 
        515                 520                 525             


Phe Leu Asn Val Val Gln Ala Val Ser Gln Glu Gly Ala Cys Val Tyr 
    530                 535                 540                 


Ala Val Ser Asp Leu Arg Lys Ser Gly Glu Ala Ala Gly Tyr 
545                 550                 555             


<210>  2209
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2209

Ser Gly Pro Arg Gly Val Gln Ala Leu Leu Cys Ala Cys Thr Ser Cys 
1               5                   10                  15      


Leu Gln Ala Asn Tyr Thr Cys Glu Thr Asp Gly Ala Cys Met Val Ser 
            20                  25                  30          


Ile Phe Asn Leu Asp Gly Met Glu His His Val Arg Thr Cys Ile Pro 
        35                  40                  45              


Lys Val Glu Leu Val Pro Ala Gly Lys Pro Phe Tyr Cys Leu Ser Ser 
    50                  55                  60                  


Glu Asp Leu Arg Asn Thr His Cys Cys Tyr Thr Asp Tyr Cys Asn Arg 
65                  70                  75                  80  


Ile Asp Leu Arg Val Pro Ser Gly His Leu Lys Glu Pro Glu His Pro 
                85                  90                  95      


Ser Met Trp Gly Pro Val Glu 
            100             


<210>  2210
<211>  399
<212>  PRT
<213>  Homo Sapiens

<400>  2210

Gln Asn Pro Ala Ser Pro Pro Glu Glu Gly Ser Pro Asp Pro Asp Ser 
1               5                   10                  15      


Thr Gly Ala Leu Val Glu Glu Glu Asp Pro Phe Phe Lys Val Pro Val 
            20                  25                  30          


Asn Lys Leu Ala Ala Ala Val Ser Asn Phe Gly Tyr Asp Leu Tyr Arg 
        35                  40                  45              


Val Arg Ser Ser Thr Ser Pro Thr Thr Asn Val Leu Leu Ser Pro Leu 
    50                  55                  60                  


Ser Val Ala Thr Ala Leu Ser Ala Leu Ser Leu Gly Ala Glu Gln Arg 
65                  70                  75                  80  


Thr Glu Ser Ile Ile His Arg Ala Leu Tyr Tyr Asp Leu Ile Ser Ser 
                85                  90                  95      


Pro Asp Ile His Gly Thr Tyr Lys Glu Leu Leu Asp Thr Val Thr Ala 
            100                 105                 110         


Pro Gln Lys Asn Leu Lys Ser Ala Ser Arg Ile Val Phe Glu Lys Lys 
        115                 120                 125             


Leu Arg Ile Lys Ser Ser Phe Val Ala Pro Leu Glu Lys Ser Tyr Gly 
    130                 135                 140                 


Thr Arg Pro Arg Val Leu Thr Gly Asn Pro Arg Leu Asp Leu Gln Glu 
145                 150                 155                 160 


Ile Asn Asn Trp Val Gln Ala Gln Met Lys Gly Lys Leu Ala Arg Ser 
                165                 170                 175     


Thr Lys Glu Ile Pro Asp Glu Ile Ser Ile Leu Leu Leu Gly Val Ala 
            180                 185                 190         


His Phe Lys Gly Gln Trp Val Thr Lys Phe Asp Ser Arg Lys Thr Ser 
        195                 200                 205             


Leu Glu Asp Phe Tyr Leu Asp Glu Glu Arg Thr Val Arg Val Pro Met 
    210                 215                 220                 


Met Ser Asp Pro Lys Ala Val Leu Arg Tyr Gly Leu Asp Ser Asp Leu 
225                 230                 235                 240 


Ser Cys Lys Ile Ala Gln Leu Pro Leu Thr Gly Ser Met Ser Ile Ile 
                245                 250                 255     


Phe Phe Leu Pro Leu Lys Val Thr Gln Asn Leu Thr Leu Ile Glu Glu 
            260                 265                 270         


Ser Leu Thr Ser Glu Phe Ile His Asp Ile Asp Arg Glu Leu Lys Thr 
        275                 280                 285             


Val Gln Ala Val Leu Thr Val Pro Lys Leu Lys Leu Ser Tyr Glu Gly 
    290                 295                 300                 


Glu Val Thr Lys Ser Leu Gln Glu Met Lys Leu Gln Ser Leu Phe Asp 
305                 310                 315                 320 


Ser Pro Asp Phe Ser Lys Ile Thr Gly Lys Pro Ile Lys Leu Thr Gln 
                325                 330                 335     


Val Glu His Arg Ala Gly Phe Glu Trp Asn Glu Asp Gly Ala Gly Thr 
            340                 345                 350         


Thr Pro Ser Pro Gly Leu Gln Pro Ala His Leu Thr Phe Pro Leu Asp 
        355                 360                 365             


Tyr His Leu Asn Gln Pro Phe Ile Phe Val Leu Arg Asp Thr Asp Thr 
    370                 375                 380                 


Gly Ala Leu Leu Phe Ile Gly Lys Ile Leu Asp Pro Arg Gly Pro 
385                 390                 395                 


<210>  2211
<211>  252
<212>  PRT
<213>  Homo Sapiens

<400>  2211

Glu Ala Met Phe Cys Asp Phe Pro Lys Ile Asn His Gly Ile Leu Tyr 
1               5                   10                  15      


Asp Glu Glu Lys Tyr Lys Pro Phe Ser Gln Val Pro Thr Gly Glu Val 
            20                  25                  30          


Phe Tyr Tyr Ser Cys Glu Tyr Asn Phe Val Ser Pro Ser Lys Ser Phe 
        35                  40                  45              


Trp Thr Arg Ile Thr Cys Ala Glu Glu Gly Trp Ser Pro Thr Pro Lys 
    50                  55                  60                  


Cys Leu Arg Leu Cys Phe Phe Pro Phe Val Glu Asn Gly His Ser Glu 
65                  70                  75                  80  


Ser Ser Gly Gln Thr His Leu Glu Gly Asp Thr Val Gln Ile Ile Cys 
                85                  90                  95      


Asn Thr Gly Tyr Arg Leu Gln Asn Asn Glu Asn Asn Ile Ser Cys Val 
            100                 105                 110         


Glu Arg Gly Trp Ser Thr Pro Pro Lys Cys Arg Ser Thr Ile Ser Ala 
        115                 120                 125             


Glu Lys Cys Gly Pro Pro Pro Pro Ile Asp Asn Gly Asp Ile Thr Ser 
    130                 135                 140                 


Phe Leu Leu Ser Val Tyr Ala Pro Gly Ser Ser Val Glu Tyr Gln Cys 
145                 150                 155                 160 


Gln Asn Leu Tyr Gln Leu Glu Gly Asn Asn Gln Ile Thr Cys Arg Asn 
                165                 170                 175     


Gly Gln Trp Ser Glu Pro Pro Lys Cys Leu Asp Pro Cys Val Ile Ser 
            180                 185                 190         


Gln Glu Ile Met Glu Lys Tyr Asn Ile Lys Leu Lys Trp Thr Asn Gln 
        195                 200                 205             


Gln Lys Leu Tyr Ser Arg Thr Gly Asp Ile Val Glu Phe Val Cys Lys 
    210                 215                 220                 


Ser Gly Tyr His Pro Thr Lys Ser His Ser Phe Arg Ala Met Cys Gln 
225                 230                 235                 240 


Asn Gly Lys Leu Val Tyr Pro Ser Cys Glu Glu Lys 
                245                 250         


<210>  2212
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  2212

Asp Pro Val Lys Pro Ser Arg Gly Pro Leu Val Thr Cys Thr Cys Glu 
1               5                   10                  15      


Ser Pro His Cys Lys Gly Pro Thr Cys Arg Gly Ala Trp Cys Thr Val 
            20                  25                  30          


Val Leu Val Arg Glu Glu Gly Arg His Pro Gln Glu His Arg Gly Cys 
        35                  40                  45              


Gly Asn Leu His Arg Glu Leu Cys Arg Gly Arg Pro Thr Glu Phe Val 
    50                  55                  60                  


Asn His Tyr Cys Cys Asp Ser His Leu Cys Asn His Asn Val Ser Leu 
65                  70                  75                  80  


Val Leu Glu Ala Thr Gln Pro Pro Ser Glu Gln Pro Gly Thr Asp Gly 
                85                  90                  95      


Gln 
    


<210>  2213
<211>  140
<212>  PRT
<213>  Homo Sapiens

<400>  2213

Met Asp Val Phe Met Lys Gly Leu Ser Lys Ala Lys Glu Gly Val Val 
1               5                   10                  15      


Ala Ala Ala Glu Lys Thr Lys Gln Gly Val Ala Glu Ala Ala Gly Lys 
            20                  25                  30          


Thr Lys Glu Gly Val Leu Tyr Val Gly Ser Lys Thr Lys Glu Gly Val 
        35                  40                  45              


Val His Gly Val Ala Thr Val Ala Glu Lys Thr Lys Glu Gln Val Thr 
    50                  55                  60                  


Asn Val Gly Gly Ala Val Val Thr Gly Val Thr Ala Val Ala Gln Lys 
65                  70                  75                  80  


Thr Val Glu Gly Ala Gly Ser Ile Ala Ala Ala Thr Gly Phe Val Lys 
                85                  90                  95      


Lys Asp Gln Leu Gly Lys Asn Glu Glu Gly Ala Pro Gln Glu Gly Ile 
            100                 105                 110         


Leu Glu Asp Met Pro Val Asp Pro Asp Asn Glu Ala Tyr Glu Met Pro 
        115                 120                 125             


Ser Glu Glu Gly Tyr Gln Asp Tyr Glu Pro Glu Ala 
    130                 135                 140 


<210>  2214
<211>  455
<212>  PRT
<213>  Homo Sapiens

<400>  2214

Leu Asn Phe Arg Ala Pro Pro Val Ile Pro Asn Val Pro Phe Leu Trp 
1               5                   10                  15      


Ala Trp Asn Ala Pro Ser Glu Phe Cys Leu Gly Lys Phe Asp Glu Pro 
            20                  25                  30          


Leu Asp Met Ser Leu Phe Ser Phe Ile Gly Ser Pro Arg Ile Asn Ala 
        35                  40                  45              


Thr Gly Gln Gly Val Thr Ile Phe Tyr Val Asp Arg Leu Gly Tyr Tyr 
    50                  55                  60                  


Pro Tyr Ile Asp Ser Ile Thr Gly Val Thr Val Asn Gly Gly Ile Pro 
65                  70                  75                  80  


Gln Lys Ile Ser Leu Gln Asp His Leu Asp Lys Ala Lys Lys Asp Ile 
                85                  90                  95      


Thr Phe Tyr Met Pro Val Asp Asn Leu Gly Met Ala Val Ile Asp Trp 
            100                 105                 110         


Glu Glu Trp Arg Pro Thr Trp Ala Arg Asn Trp Lys Pro Lys Asp Val 
        115                 120                 125             


Tyr Lys Asn Arg Ser Ile Glu Leu Val Gln Gln Gln Asn Val Gln Leu 
    130                 135                 140                 


Ser Leu Thr Glu Ala Thr Glu Lys Ala Lys Gln Glu Phe Glu Lys Ala 
145                 150                 155                 160 


Gly Lys Asp Phe Leu Val Glu Thr Ile Lys Leu Gly Lys Leu Leu Arg 
                165                 170                 175     


Pro Asn His Leu Trp Gly Tyr Tyr Leu Phe Pro Asp Cys Tyr Asn His 
            180                 185                 190         


His Tyr Lys Lys Pro Gly Tyr Asn Gly Ser Cys Phe Asn Val Glu Ile 
        195                 200                 205             


Lys Arg Asn Asp Asp Leu Ser Trp Leu Trp Asn Glu Ser Thr Ala Leu 
    210                 215                 220                 


Tyr Pro Ser Ile Tyr Leu Asn Thr Gln Gln Ser Pro Val Ala Ala Thr 
225                 230                 235                 240 


Leu Tyr Val Arg Asn Arg Val Arg Glu Ala Ile Arg Val Ser Lys Ile 
                245                 250                 255     


Pro Asp Ala Lys Ser Pro Leu Pro Val Phe Ala Tyr Thr Arg Ile Val 
            260                 265                 270         


Phe Thr Asp Gln Val Leu Lys Phe Leu Ser Gln Asp Glu Leu Val Tyr 
        275                 280                 285             


Thr Phe Gly Glu Thr Val Ala Leu Gly Ala Ser Gly Ile Val Ile Trp 
    290                 295                 300                 


Gly Thr Leu Ser Ile Met Arg Ser Met Lys Ser Cys Leu Leu Leu Asp 
305                 310                 315                 320 


Asn Tyr Met Glu Thr Ile Leu Asn Pro Tyr Ile Ile Asn Val Thr Leu 
                325                 330                 335     


Ala Ala Lys Met Cys Ser Gln Val Leu Cys Gln Glu Gln Gly Val Cys 
            340                 345                 350         


Ile Arg Lys Asn Trp Asn Ser Ser Asp Tyr Leu His Leu Asn Pro Asp 
        355                 360                 365             


Asn Phe Ala Ile Gln Leu Glu Lys Gly Gly Lys Phe Thr Val Arg Gly 
    370                 375                 380                 


Lys Pro Thr Leu Glu Asp Leu Glu Gln Phe Ser Glu Lys Phe Tyr Cys 
385                 390                 395                 400 


Ser Cys Tyr Ser Thr Leu Ser Cys Lys Glu Lys Ala Asp Val Lys Asp 
                405                 410                 415     


Thr Asp Ala Val Asp Val Cys Ile Ala Asp Gly Val Cys Ile Asp Ala 
            420                 425                 430         


Phe Leu Lys Pro Pro Met Glu Thr Glu Glu Pro Gln Ile Phe Tyr Asn 
        435                 440                 445             


Ala Ser Pro Ser Thr Leu Ser 
    450                 455 


<210>  2215
<211>  376
<212>  PRT
<213>  Homo Sapiens

<400>  2215

Gly Lys Leu Thr Ala Leu Asp Pro Glu Thr Asn Met Asn Val Ser Glu 
1               5                   10                  15      


Ile Ile Ser Tyr Trp Gly Phe Pro Ser Glu Glu Tyr Leu Val Glu Thr 
            20                  25                  30          


Glu Asp Gly Tyr Ile Leu Cys Leu Asn Arg Ile Pro His Gly Arg Lys 
        35                  40                  45              


Asn His Ser Asp Lys Gly Pro Lys Pro Val Val Phe Leu Gln His Gly 
    50                  55                  60                  


Leu Leu Ala Asp Ser Ser Asn Trp Val Thr Asn Leu Ala Asn Ser Ser 
65                  70                  75                  80  


Leu Gly Phe Ile Leu Ala Asp Ala Gly Phe Asp Val Trp Met Gly Asn 
                85                  90                  95      


Ser Arg Gly Asn Thr Trp Ser Arg Lys His Lys Thr Leu Ser Val Ser 
            100                 105                 110         


Gln Asp Glu Phe Trp Ala Phe Ser Tyr Asp Glu Met Ala Lys Tyr Asp 
        115                 120                 125             


Leu Pro Ala Ser Ile Asn Phe Ile Leu Asn Lys Thr Gly Gln Glu Gln 
    130                 135                 140                 


Val Tyr Tyr Val Gly His Ser Gln Gly Thr Thr Ile Gly Phe Ile Ala 
145                 150                 155                 160 


Phe Ser Gln Ile Pro Glu Leu Ala Lys Arg Ile Lys Met Phe Phe Ala 
                165                 170                 175     


Leu Gly Pro Val Ala Ser Val Ala Phe Cys Thr Ser Pro Met Ala Lys 
            180                 185                 190         


Leu Gly Arg Leu Pro Asp His Leu Ile Lys Asp Leu Phe Gly Asp Lys 
        195                 200                 205             


Glu Phe Leu Pro Gln Ser Ala Phe Leu Lys Trp Leu Gly Thr His Val 
    210                 215                 220                 


Cys Thr His Val Ile Leu Lys Glu Leu Cys Gly Asn Leu Cys Phe Leu 
225                 230                 235                 240 


Leu Cys Gly Phe Asn Glu Arg Asn Leu Asn Met Ser Arg Val Asp Val 
                245                 250                 255     


Tyr Thr Thr His Ser Pro Ala Gly Thr Ser Val Gln Asn Met Leu His 
            260                 265                 270         


Trp Ser Gln Ala Val Lys Phe Gln Lys Phe Gln Ala Phe Asp Trp Gly 
        275                 280                 285             


Ser Ser Ala Lys Asn Tyr Phe His Tyr Asn Gln Ser Tyr Pro Pro Thr 
    290                 295                 300                 


Tyr Asn Val Lys Asp Met Leu Val Pro Thr Ala Val Trp Ser Gly Gly 
305                 310                 315                 320 


His Asp Trp Leu Ala Asp Val Tyr Asp Val Asn Ile Leu Leu Thr Gln 
                325                 330                 335     


Ile Thr Asn Leu Val Phe His Glu Ser Ile Pro Glu Trp Glu His Leu 
            340                 345                 350         


Asp Phe Ile Trp Gly Leu Asp Ala Pro Trp Arg Leu Tyr Asn Lys Ile 
        355                 360                 365             


Ile Asn Leu Met Arg Lys Tyr Gln 
    370                 375     


<210>  2216
<211>  531
<212>  PRT
<213>  Homo Sapiens

<400>  2216

Gln Thr Ala Pro Gln Val Leu Arg Ile Gly Gly Ile Phe Glu Thr Val 
1               5                   10                  15      


Glu Asn Glu Pro Val Asn Val Glu Glu Leu Ala Phe Lys Phe Ala Val 
            20                  25                  30          


Thr Ser Ile Asn Arg Asn Arg Thr Leu Met Pro Asn Thr Thr Leu Thr 
        35                  40                  45              


Tyr Asp Ile Gln Arg Ile Asn Leu Phe Asp Ser Phe Glu Ala Ser Arg 
    50                  55                  60                  


Arg Ala Cys Asp Gln Leu Ala Leu Gly Val Ala Ala Leu Phe Gly Pro 
65                  70                  75                  80  


Ser His Ser Ser Ser Val Ser Ala Val Gln Ser Ile Cys Asn Ala Leu 
                85                  90                  95      


Glu Val Pro His Ile Gln Thr Arg Trp Lys His Pro Ser Val Asp Asn 
            100                 105                 110         


Lys Asp Leu Phe Tyr Ile Asn Leu Tyr Pro Asp Tyr Ala Ala Ile Ser 
        115                 120                 125             


Arg Ala Ile Leu Asp Leu Val Leu Tyr Tyr Asn Trp Lys Thr Val Thr 
    130                 135                 140                 


Val Val Tyr Glu Asp Ser Thr Gly Leu Ile Arg Leu Gln Glu Leu Ile 
145                 150                 155                 160 


Lys Ala Pro Ser Arg Tyr Asn Ile Lys Ile Lys Ile Arg Gln Leu Pro 
                165                 170                 175     


Ser Gly Asn Lys Asp Ala Lys Pro Leu Leu Lys Glu Met Lys Lys Gly 
            180                 185                 190         


Lys Glu Phe Tyr Val Ile Phe Asp Cys Ser His Glu Thr Ala Ala Glu 
        195                 200                 205             


Ile Leu Lys Gln Ile Leu Phe Met Gly Met Met Thr Glu Tyr Tyr His 
    210                 215                 220                 


Tyr Phe Phe Thr Thr Leu Asp Leu Phe Ala Leu Asp Leu Glu Leu Tyr 
225                 230                 235                 240 


Arg Tyr Ser Gly Val Asn Met Thr Gly Phe Arg Leu Leu Asn Ile Asp 
                245                 250                 255     


Asn Pro His Val Ser Ser Ile Ile Glu Lys Trp Ser Met Glu Arg Leu 
            260                 265                 270         


Gln Ala Pro Pro Arg Pro Glu Thr Gly Leu Leu Asp Gly Met Met Thr 
        275                 280                 285             


Thr Glu Ala Ala Leu Met Tyr Asp Ala Val Tyr Met Val Ala Ile Ala 
    290                 295                 300                 


Ser His Arg Ala Ser Gln Leu Thr Val Ser Ser Leu Gln Cys His Arg 
305                 310                 315                 320 


His Lys Pro Trp Arg Leu Gly Pro Arg Phe Met Asn Leu Ile Lys Glu 
                325                 330                 335     


Ala Arg Trp Asp Gly Leu Thr Gly His Ile Thr Phe Asn Lys Thr Asn 
            340                 345                 350         


Gly Leu Arg Lys Asp Phe Asp Leu Asp Ile Ile Ser Leu Lys Glu Glu 
        355                 360                 365             


Gly Thr Glu Lys Ile Gly Ile Trp Asn Ser Asn Ser Gly Leu Asn Met 
    370                 375                 380                 


Thr Asp Ser Asn Lys Asp Lys Ser Ser Asn Ile Thr Asp Ser Leu Ala 
385                 390                 395                 400 


Asn Arg Thr Leu Ile Val Thr Thr Ile Leu Glu Glu Pro Tyr Val Met 
                405                 410                 415     


Tyr Arg Lys Ser Asp Lys Pro Leu Tyr Gly Asn Asp Arg Phe Glu Gly 
            420                 425                 430         


Tyr Cys Leu Asp Leu Leu Lys Glu Leu Ser Asn Ile Leu Gly Phe Ile 
        435                 440                 445             


Tyr Asp Val Lys Leu Val Pro Asp Gly Lys Tyr Gly Ala Gln Asn Asp 
    450                 455                 460                 


Lys Gly Glu Trp Asn Gly Met Val Lys Glu Leu Ile Asp His Arg Ala 
465                 470                 475                 480 


Asp Leu Ala Val Ala Pro Leu Thr Ile Thr Tyr Val Arg Glu Lys Val 
                485                 490                 495     


Ile Asp Phe Ser Lys Pro Phe Met Thr Leu Gly Ile Ser Ile Leu Tyr 
            500                 505                 510         


Arg Lys Pro Asn Gly Thr Asn Pro Gly Val Phe Ser Phe Leu Asn Pro 
        515                 520                 525             


Leu Ser Pro 
    530     


<210>  2217
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  2217

Gly Leu Leu Asp Leu Lys Ser Met Ile Glu Lys Val Thr Gly Lys Asn 
1               5                   10                  15      


Ala Leu Thr Asn Tyr Gly Phe Tyr Gly Cys Tyr Cys Gly Trp Gly Gly 
            20                  25                  30          


Arg Gly Thr Pro Lys Asp Gly Thr Asp Trp Cys Cys Trp Ala His Asp 
        35                  40                  45              


His Cys Tyr Gly Arg Leu Glu Glu Lys Gly Cys Asn Ile Arg Thr Gln 
    50                  55                  60                  


Ser Tyr Lys Tyr Arg Phe Ala Trp Gly Val Val Thr Cys Glu Pro Gly 
65                  70                  75                  80  


Pro Phe Cys His Val Asn Leu Cys Ala Cys Asp Arg Lys Leu Val Tyr 
                85                  90                  95      


Cys Leu Lys Arg Asn Leu Arg Ser Tyr Asn Pro Gln Tyr Gln Tyr Phe 
            100                 105                 110         


Pro Asn Ile Leu Cys Ser 
        115             


<210>  2218
<211>  365
<212>  PRT
<213>  Homo Sapiens

<400>  2218

Gly Pro Val Trp Arg Lys His Tyr Ile Thr Tyr Arg Ile Asn Asn Tyr 
1               5                   10                  15      


Thr Pro Asp Met Asn Arg Glu Asp Val Asp Tyr Ala Ile Arg Lys Ala 
            20                  25                  30          


Phe Gln Val Trp Ser Asn Val Thr Pro Leu Lys Phe Ser Lys Ile Asn 
        35                  40                  45              


Thr Gly Met Ala Asp Ile Leu Val Val Phe Ala Arg Gly Ala His Gly 
    50                  55                  60                  


Asp Phe His Ala Phe Asp Gly Lys Gly Gly Ile Leu Ala His Ala Phe 
65                  70                  75                  80  


Gly Pro Gly Ser Gly Ile Gly Gly Asp Ala His Phe Asp Glu Asp Glu 
                85                  90                  95      


Phe Trp Thr Thr His Ser Gly Gly Thr Asn Leu Phe Leu Thr Ala Val 
            100                 105                 110         


His Glu Ile Gly His Ser Leu Gly Leu Gly His Ser Ser Asp Pro Lys 
        115                 120                 125             


Ala Val Met Phe Pro Thr Tyr Lys Tyr Val Asp Ile Asn Thr Phe Arg 
    130                 135                 140                 


Leu Ser Ala Asp Asp Ile Arg Gly Ile Gln Ser Leu Tyr Gly Asp Pro 
145                 150                 155                 160 


Lys Glu Asn Gln Arg Leu Pro Asn Pro Asp Asn Ser Glu Pro Ala Leu 
                165                 170                 175     


Cys Asp Pro Asn Leu Ser Phe Asp Ala Val Thr Thr Val Gly Asn Lys 
            180                 185                 190         


Ile Phe Phe Phe Lys Asp Arg Phe Phe Trp Leu Lys Val Ser Glu Arg 
        195                 200                 205             


Pro Lys Thr Ser Val Asn Leu Ile Ser Ser Leu Trp Pro Thr Leu Pro 
    210                 215                 220                 


Ser Gly Ile Glu Ala Ala Tyr Glu Ile Glu Ala Arg Asn Gln Val Phe 
225                 230                 235                 240 


Leu Phe Lys Asp Asp Lys Tyr Trp Leu Ile Ser Asn Leu Arg Pro Glu 
                245                 250                 255     


Pro Asn Tyr Pro Lys Ser Ile His Ser Phe Gly Phe Pro Asn Phe Val 
            260                 265                 270         


Lys Lys Ile Asp Ala Ala Val Phe Asn Pro Arg Phe Tyr Arg Thr Tyr 
        275                 280                 285             


Phe Phe Val Asp Asn Gln Tyr Trp Arg Tyr Asp Glu Arg Arg Gln Met 
    290                 295                 300                 


Met Asp Pro Gly Tyr Pro Lys Leu Ile Thr Lys Asn Phe Gln Gly Ile 
305                 310                 315                 320 


Gly Pro Lys Ile Asp Ala Val Phe Tyr Ser Lys Asn Lys Tyr Tyr Tyr 
                325                 330                 335     


Phe Phe Gln Gly Ser Asn Gln Phe Glu Tyr Asp Phe Leu Leu Gln Arg 
            340                 345                 350         


Ile Thr Lys Thr Leu Lys Ser Asn Ser Trp Phe Gly Cys 
        355                 360                 365 


<210>  2219
<211>  231
<212>  PRT
<213>  Homo Sapiens

<400>  2219

Ile Val Asn Gly Glu Asn Ala Val Leu Gly Ser Trp Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Gln Asp Ser Ser Gly Phe His Phe Cys Gly Gly Ser Leu Ile 
            20                  25                  30          


Ser Gln Ser Trp Val Val Thr Ala Ala His Cys Asn Val Ser Pro Gly 
        35                  40                  45              


Arg His Phe Val Val Leu Gly Glu Tyr Asp Arg Ser Ser Asn Ala Glu 
    50                  55                  60                  


Pro Leu Gln Val Leu Ser Val Ser Arg Ala Ile Thr His Pro Ser Trp 
65                  70                  75                  80  


Asn Ser Thr Thr Met Asn Asn Asp Val Thr Leu Leu Lys Leu Ala Ser 
                85                  90                  95      


Pro Ala Gln Tyr Thr Thr Arg Ile Ser Pro Val Cys Leu Ala Ser Ser 
            100                 105                 110         


Asn Glu Ala Leu Thr Glu Gly Leu Thr Cys Val Thr Thr Gly Trp Gly 
        115                 120                 125             


Arg Leu Ser Gly Val Gly Asn Val Thr Pro Ala His Leu Gln Gln Val 
    130                 135                 140                 


Ala Leu Pro Leu Val Thr Val Asn Gln Cys Arg Gln Tyr Trp Gly Ser 
145                 150                 155                 160 


Ser Ile Thr Asp Ser Met Ile Cys Ala Gly Gly Ala Gly Ala Ser Ser 
                165                 170                 175     


Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Gln Lys Gly Asn Thr 
            180                 185                 190         


Trp Val Leu Ile Gly Ile Val Ser Trp Gly Thr Lys Asn Cys Asn Val 
        195                 200                 205             


Arg Ala Pro Ala Val Tyr Thr Arg Val Ser Lys Phe Ser Thr Trp Ile 
    210                 215                 220                 


Asn Gln Val Ile Ala Tyr Asn 
225                 230     


<210>  2220
<211>  146
<212>  PRT
<213>  Homo Sapiens

<400>  2220

Val Pro Ile Gln Lys Val Gln Asp Asp Thr Lys Thr Leu Ile Lys Thr 
1               5                   10                  15      


Ile Val Thr Arg Ile Asn Asp Ile Ser His Thr Gln Ser Val Ser Ser 
            20                  25                  30          


Lys Gln Lys Val Thr Gly Leu Asp Phe Ile Pro Gly Leu His Pro Ile 
        35                  40                  45              


Leu Thr Leu Ser Lys Met Asp Gln Thr Leu Ala Val Tyr Gln Gln Ile 
    50                  55                  60                  


Leu Thr Ser Met Pro Ser Arg Asn Val Ile Gln Ile Ser Asn Asp Leu 
65                  70                  75                  80  


Glu Asn Leu Arg Asp Leu Leu His Val Leu Ala Phe Ser Lys Ser Cys 
                85                  90                  95      


His Leu Pro Trp Ala Ser Gly Leu Glu Thr Leu Asp Ser Leu Gly Gly 
            100                 105                 110         


Val Leu Glu Ala Ser Gly Tyr Ser Thr Glu Val Val Ala Leu Ser Arg 
        115                 120                 125             


Leu Gln Gly Ser Leu Gln Asp Met Leu Trp Gln Leu Asp Leu Ser Pro 
    130                 135                 140                 


Gly Cys 
145     


<210>  2221
<211>  319
<212>  PRT
<213>  Homo Sapiens

<400>  2221

Ile Ile Gly Ala Gln Pro Leu Cys Ser Gln Leu Ala Gly Leu Ser Gln 
1               5                   10                  15      


Gly Gln Lys Lys Leu Cys His Leu Tyr Gln Asp His Met Gln Tyr Ile 
            20                  25                  30          


Gly Glu Gly Ala Lys Thr Gly Ile Lys Glu Cys Gln Tyr Gln Phe Arg 
        35                  40                  45              


His Arg Arg Trp Asn Cys Ser Thr Val Asp Asn Thr Ser Val Phe Gly 
    50                  55                  60                  


Arg Val Met Gln Ile Gly Ser Arg Glu Thr Ala Phe Thr Tyr Ala Val 
65                  70                  75                  80  


Ser Ala Ala Gly Val Val Asn Ala Met Ser Arg Ala Cys Arg Glu Gly 
                85                  90                  95      


Glu Leu Ser Thr Cys Gly Cys Ser Arg Ala Ala Arg Pro Lys Asp Leu 
            100                 105                 110         


Pro Arg Asp Trp Leu Trp Gly Gly Cys Gly Asp Asn Ile Asp Tyr Gly 
        115                 120                 125             


Tyr Arg Phe Ala Lys Glu Phe Val Asp Ala Arg Glu Arg Glu Arg Ile 
    130                 135                 140                 


His Ala Lys Gly Ser Tyr Glu Ser Ala Arg Ile Leu Met Asn Leu His 
145                 150                 155                 160 


Asn Asn Glu Ala Gly Arg Arg Thr Val Tyr Asn Leu Ala Asp Val Ala 
                165                 170                 175     


Cys Lys Cys His Gly Val Ser Gly Ser Cys Ser Leu Lys Thr Cys Trp 
            180                 185                 190         


Leu Gln Leu Ala Asp Phe Arg Lys Val Gly Asp Ala Leu Lys Glu Lys 
        195                 200                 205             


Tyr Asp Ser Ala Ala Ala Met Arg Leu Asn Ser Arg Gly Lys Leu Val 
    210                 215                 220                 


Gln Val Asn Ser Arg Phe Asn Ser Pro Thr Thr Gln Asp Leu Val Tyr 
225                 230                 235                 240 


Ile Asp Pro Ser Pro Asp Tyr Cys Val Arg Asn Glu Ser Thr Gly Ser 
                245                 250                 255     


Leu Gly Thr Gln Gly Arg Leu Cys Asn Lys Thr Ser Glu Gly Met Asp 
            260                 265                 270         


Gly Cys Glu Leu Met Cys Cys Gly Arg Gly Tyr Asp Gln Phe Lys Thr 
        275                 280                 285             


Val Gln Thr Glu Arg Cys His Cys Lys Phe His Trp Cys Cys Tyr Val 
    290                 295                 300                 


Lys Cys Lys Lys Cys Thr Glu Ile Val Asp Gln Phe Val Cys Lys 
305                 310                 315                 


<210>  2222
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  2222

Ala Pro Glu Ala Gln Val Ser Val Gln Pro Asn Phe Gln Gln Asp Lys 
1               5                   10                  15      


Phe Leu Gly Arg Trp Phe Ser Ala Gly Leu Ala Ser Asn Ser Ser Trp 
            20                  25                  30          


Leu Arg Glu Lys Lys Ala Ala Leu Ser Met Cys Lys Ser Val Val Ala 
        35                  40                  45              


Pro Ala Thr Asp Gly Gly Leu Asn Leu Thr Ser Thr Phe Leu Arg Lys 
    50                  55                  60                  


Asn Gln Cys Glu Thr Arg Thr Met Leu Leu Gln Pro Ala Gly Ser Leu 
65                  70                  75                  80  


Gly Ser Tyr Ser Tyr Arg Ser Pro His Trp Gly Ser Thr Tyr Ser Val 
                85                  90                  95      


Ser Val Val Glu Thr Asp Tyr Asp Gln Tyr Ala Leu Leu Tyr Ser Gln 
            100                 105                 110         


Gly Ser Lys Gly Pro Gly Glu Asp Phe Arg Met Ala Thr Leu Tyr Ser 
        115                 120                 125             


Arg Thr Gln Thr Pro Arg Ala Glu Leu Lys Glu Lys Phe Thr Ala Phe 
    130                 135                 140                 


Cys Lys Ala Gln Gly Phe Thr Glu Asp Thr Ile Val Phe Leu Pro Gln 
145                 150                 155                 160 


Thr Asp Lys Cys Met Thr Glu Gln 
                165             


<210>  2223
<211>  220
<212>  PRT
<213>  Homo Sapiens

<400>  2223

Ser Ala Arg Ala Arg Thr Asp Leu Leu Asn Val Cys Met Asn Ala Lys 
1               5                   10                  15      


His His Lys Thr Gln Pro Ser Pro Glu Asp Glu Leu Tyr Gly Gln Cys 
            20                  25                  30          


Ser Pro Trp Lys Lys Asn Ala Cys Cys Thr Ala Ser Thr Ser Gln Glu 
        35                  40                  45              


Leu His Lys Asp Thr Ser Arg Leu Tyr Asn Phe Asn Trp Asp His Cys 
    50                  55                  60                  


Gly Lys Met Glu Pro Thr Cys Lys Arg His Phe Ile Gln Asp Ser Cys 
65                  70                  75                  80  


Leu Tyr Glu Cys Ser Pro Asn Leu Gly Pro Trp Ile Arg Gln Val Asn 
                85                  90                  95      


Gln Ser Trp Arg Lys Glu Arg Ile Leu Asn Val Pro Leu Cys Lys Glu 
            100                 105                 110         


Asp Cys Glu Arg Trp Trp Glu Asp Cys Arg Thr Ser Tyr Thr Cys Lys 
        115                 120                 125             


Ser Asn Trp His Lys Gly Trp Asn Trp Thr Ser Gly Ile Asn Glu Cys 
    130                 135                 140                 


Pro Ala Gly Ala Leu Cys Ser Thr Phe Glu Ser Tyr Phe Pro Thr Pro 
145                 150                 155                 160 


Ala Ala Leu Cys Glu Gly Leu Trp Ser His Ser Phe Lys Val Ser Asn 
                165                 170                 175     


Tyr Ser Arg Gly Ser Gly Arg Cys Ile Gln Met Trp Phe Asp Ser Ala 
            180                 185                 190         


Gln Gly Asn Pro Asn Glu Glu Val Ala Lys Phe Tyr Ala Ala Ala Met 
        195                 200                 205             


Asn Ala Gly Ala Pro Ser Arg Gly Ile Ile Asp Ser 
    210                 215                 220 


<210>  2224
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  2224

His Leu Pro Pro Glu Glu Lys Leu Arg Asp Asp Arg Ser Leu Arg Ser 
1               5                   10                  15      


Asn Ser Ser Val Asn Leu Leu Asp Val Pro Ser Val Ser Ile Val Ala 
            20                  25                  30          


Leu Asn Lys Lys Ser Lys Gln Ile Gly Arg Lys Ala Ala Glu Lys Lys 
        35                  40                  45              


Arg Ser Ser Lys Lys Glu Ala Ser Met Lys Lys Val Val Arg Pro Arg 
    50                  55                  60                  


Thr Pro Leu Ser Ala Pro Cys Val Ala Thr Arg Asn Ser Cys Lys Pro 
65                  70                  75                  80  


Pro Ala Pro Ala Cys Cys Asp Pro Cys Ala Ser Cys Gln Cys Arg Phe 
                85                  90                  95      


Phe Arg Ser Ala Cys Ser Cys Arg Val Leu Ser Leu Asn Cys 
            100                 105                 110 


<210>  2225
<211>  518
<212>  PRT
<213>  Homo Sapiens

<400>  2225

Ala Asn Phe Pro Asn Asn Ile Gln Ile Gly Gly Leu Phe Pro Asn Gln 
1               5                   10                  15      


Gln Ser Gln Glu His Ala Ala Phe Arg Phe Ala Leu Ser Gln Leu Thr 
            20                  25                  30          


Glu Pro Pro Lys Leu Leu Pro Gln Ile Asp Ile Val Asn Ile Ser Asp 
        35                  40                  45              


Ser Phe Glu Met Thr Tyr Arg Phe Cys Ser Gln Phe Ser Lys Gly Val 
    50                  55                  60                  


Tyr Ala Ile Phe Gly Phe Tyr Glu Arg Arg Thr Val Asn Met Leu Thr 
65                  70                  75                  80  


Ser Phe Cys Gly Ala Leu His Val Cys Phe Ile Thr Pro Ser Phe Pro 
                85                  90                  95      


Val Asp Thr Ser Asn Gln Phe Val Leu Gln Leu Arg Pro Glu Leu Gln 
            100                 105                 110         


Asp Ala Leu Ile Ser Ile Ile Asp His Tyr Lys Trp Gln Lys Phe Val 
        115                 120                 125             


Tyr Ile Tyr Asp Ala Asp Arg Gly Leu Ser Val Leu Gln Lys Val Leu 
    130                 135                 140                 


Asp Thr Ala Ala Glu Lys Asn Trp Gln Val Thr Ala Val Asn Ile Leu 
145                 150                 155                 160 


Thr Thr Thr Glu Glu Gly Tyr Arg Met Leu Phe Gln Asp Leu Glu Lys 
                165                 170                 175     


Lys Lys Glu Arg Leu Val Val Val Asp Cys Glu Ser Glu Arg Leu Asn 
            180                 185                 190         


Ala Ile Leu Gly Gln Ile Ile Lys Leu Glu Lys Asn Gly Ile Gly Tyr 
        195                 200                 205             


His Tyr Ile Leu Ala Asn Leu Gly Phe Met Asp Ile Asp Leu Asn Lys 
    210                 215                 220                 


Phe Lys Glu Ser Gly Ala Asn Val Thr Gly Phe Gln Leu Val Asn Tyr 
225                 230                 235                 240 


Thr Asp Thr Ile Pro Ala Lys Ile Met Gln Gln Trp Lys Asn Ser Asp 
                245                 250                 255     


Ala Arg Asp His Thr Arg Val Asp Trp Lys Arg Pro Lys Tyr Thr Ser 
            260                 265                 270         


Ala Leu Thr Tyr Asp Gly Val Lys Val Met Ala Glu Ala Phe Gln Ser 
        275                 280                 285             


Leu Arg Arg Gln Arg Ile Asp Ile Ser Arg Arg Gly Asn Ala Gly Asp 
    290                 295                 300                 


Cys Leu Ala Asn Pro Ala Val Pro Trp Gly Gln Gly Ile Asp Ile Gln 
305                 310                 315                 320 


Arg Ala Leu Gln Gln Val Arg Phe Glu Gly Leu Thr Gly Asn Val Gln 
                325                 330                 335     


Phe Asn Glu Lys Gly Arg Arg Thr Asn Tyr Thr Leu His Val Ile Glu 
            340                 345                 350         


Met Lys His Asp Gly Ile Arg Lys Ile Gly Tyr Trp Asn Glu Asp Asp 
        355                 360                 365             


Lys Phe Val Pro Ala Ala Thr Asp Ala Gln Ala Gly Gly Asp Asn Ser 
    370                 375                 380                 


Ser Val Gln Asn Arg Thr Tyr Ile Val Thr Thr Ile Leu Glu Asp Pro 
385                 390                 395                 400 


Tyr Val Met Leu Lys Lys Asn Ala Asn Gln Phe Glu Gly Asn Asp Arg 
                405                 410                 415     


Tyr Glu Gly Tyr Cys Val Glu Leu Ala Ala Glu Ile Ala Lys His Val 
            420                 425                 430         


Gly Tyr Ser Tyr Arg Leu Glu Ile Val Ser Asp Gly Lys Tyr Gly Ala 
        435                 440                 445             


Arg Asp Pro Asp Thr Lys Ala Trp Asn Gly Met Val Gly Glu Leu Val 
    450                 455                 460                 


Tyr Gly Arg Ala Asp Val Ala Val Ala Pro Leu Thr Ile Thr Leu Val 
465                 470                 475                 480 


Arg Glu Glu Val Ile Asp Phe Ser Lys Pro Phe Met Ser Leu Gly Ile 
                485                 490                 495     


Ser Ile Met Ile Lys Lys Pro Gln Lys Ser Lys Pro Gly Val Phe Ser 
            500                 505                 510         


Phe Leu Asp Pro Leu Ala 
        515             


<210>  2226
<211>  524
<212>  PRT
<213>  Homo Sapiens

<400>  2226

Gly Phe Pro Asn Thr Ile Ser Ile Gly Gly Leu Phe Met Arg Asn Thr 
1               5                   10                  15      


Val Gln Glu His Ser Ala Phe Arg Phe Ala Val Gln Leu Tyr Asn Thr 
            20                  25                  30          


Asn Gln Asn Thr Thr Glu Lys Pro Phe His Leu Asn Tyr His Val Asp 
        35                  40                  45              


His Leu Asp Ser Ser Asn Ser Phe Ser Val Thr Asn Ala Phe Cys Ser 
    50                  55                  60                  


Gln Phe Ser Arg Gly Val Tyr Ala Ile Phe Gly Phe Tyr Asp Gln Met 
65                  70                  75                  80  


Ser Met Asn Thr Leu Thr Ser Phe Cys Gly Ala Leu His Thr Ser Phe 
                85                  90                  95      


Val Thr Pro Ser Phe Pro Thr Asp Ala Asp Val Gln Phe Val Ile Gln 
            100                 105                 110         


Met Arg Pro Ala Leu Lys Gly Ala Ile Leu Ser Leu Leu Gly His Tyr 
        115                 120                 125             


Lys Trp Glu Lys Phe Val Tyr Leu Tyr Asp Thr Glu Arg Gly Phe Ser 
    130                 135                 140                 


Ile Leu Gln Ala Ile Met Glu Ala Ala Val Gln Asn Asn Trp Gln Val 
145                 150                 155                 160 


Thr Ala Arg Ser Val Gly Asn Ile Lys Asp Val Gln Glu Phe Arg Arg 
                165                 170                 175     


Ile Ile Glu Glu Met Asp Arg Arg Gln Glu Lys Arg Tyr Leu Ile Asp 
            180                 185                 190         


Cys Glu Val Glu Arg Ile Asn Thr Ile Leu Glu Gln Val Val Ile Leu 
        195                 200                 205             


Gly Lys His Ser Arg Gly Tyr His Tyr Met Leu Ala Asn Leu Gly Phe 
    210                 215                 220                 


Thr Asp Ile Leu Leu Glu Arg Val Met His Gly Gly Ala Asn Ile Thr 
225                 230                 235                 240 


Gly Phe Gln Ile Val Asn Asn Glu Asn Pro Met Val Gln Gln Phe Ile 
                245                 250                 255     


Gln Arg Trp Val Arg Leu Asp Glu Arg Glu Phe Pro Glu Ala Lys Asn 
            260                 265                 270         


Ala Pro Leu Lys Tyr Thr Ser Ala Leu Thr His Asp Ala Ile Leu Val 
        275                 280                 285             


Ile Ala Glu Ala Phe Arg Tyr Leu Arg Arg Gln Arg Val Asp Val Ser 
    290                 295                 300                 


Arg Arg Gly Ser Ala Gly Asp Cys Leu Ala Asn Pro Ala Val Pro Trp 
305                 310                 315                 320 


Ser Gln Gly Ile Asp Ile Glu Arg Ala Leu Lys Met Val Gln Val Gln 
                325                 330                 335     


Gly Met Thr Gly Asn Ile Gln Phe Asp Thr Tyr Gly Arg Arg Thr Asn 
            340                 345                 350         


Tyr Thr Ile Asp Val Tyr Glu Met Lys Val Ser Gly Ser Arg Lys Ala 
        355                 360                 365             


Gly Tyr Trp Asn Glu Tyr Glu Arg Phe Val Pro Phe Ser Asp Gln Gln 
    370                 375                 380                 


Ile Ser Asn Asp Ser Ala Ser Ser Glu Asn Arg Thr Ile Val Val Thr 
385                 390                 395                 400 


Thr Ile Leu Glu Ser Pro Tyr Val Met Tyr Lys Lys Asn His Glu Gln 
                405                 410                 415     


Leu Glu Gly Asn Glu Arg Tyr Glu Gly Tyr Cys Val Asp Leu Ala Tyr 
            420                 425                 430         


Glu Ile Ala Lys His Val Arg Ile Lys Tyr Lys Leu Ser Ile Val Gly 
        435                 440                 445             


Asp Gly Lys Tyr Gly Ala Arg Asp Pro Glu Thr Lys Ile Trp Asn Gly 
    450                 455                 460                 


Met Val Gly Glu Leu Val Tyr Gly Arg Ala Asp Ile Ala Val Ala Pro 
465                 470                 475                 480 


Leu Thr Ile Thr Leu Val Arg Glu Glu Val Ile Asp Phe Ser Lys Pro 
                485                 490                 495     


Phe Met Ser Leu Gly Ile Ser Ile Met Ile Lys Lys Pro Gln Lys Ser 
            500                 505                 510         


Lys Pro Gly Val Phe Ser Phe Leu Asp Pro Leu Ala 
        515                 520                 


<210>  2227
<211>  749
<212>  PRT
<213>  Homo Sapiens

<400>  2227

Leu Thr Pro Ala Glu Asp Asn Ser Leu Ser Gln Lys Lys Lys Val Thr 
1               5                   10                  15      


Val Glu Asp Leu Phe Ser Glu Asp Phe Lys Ile His Asp Pro Glu Ala 
            20                  25                  30          


Lys Trp Ile Ser Asp Thr Glu Phe Ile Tyr Arg Glu Gln Lys Gly Thr 
        35                  40                  45              


Val Arg Leu Trp Asn Val Glu Thr Asn Thr Ser Thr Val Leu Ile Glu 
    50                  55                  60                  


Gly Lys Lys Ile Glu Ser Leu Arg Ala Ile Arg Tyr Glu Ile Ser Pro 
65                  70                  75                  80  


Asp Arg Glu Tyr Ala Leu Phe Ser Tyr Asn Val Glu Pro Ile Tyr Gln 
                85                  90                  95      


His Ser Tyr Thr Gly Tyr Tyr Val Leu Ser Lys Ile Pro His Gly Asp 
            100                 105                 110         


Pro Gln Ser Leu Asp Pro Pro Glu Val Ser Asn Ala Lys Leu Gln Tyr 
        115                 120                 125             


Ala Gly Trp Gly Pro Lys Gly Gln Gln Leu Ile Phe Ile Phe Glu Asn 
    130                 135                 140                 


Asn Ile Tyr Tyr Cys Ala His Val Gly Lys Gln Ala Ile Arg Val Val 
145                 150                 155                 160 


Ser Thr Gly Lys Glu Gly Val Ile Tyr Asn Gly Leu Ser Asp Trp Leu 
                165                 170                 175     


Tyr Glu Glu Glu Ile Leu Lys Thr His Ile Ala His Trp Trp Ser Pro 
            180                 185                 190         


Asp Gly Thr Arg Leu Ala Tyr Ala Ala Ile Asn Asp Ser Arg Val Pro 
        195                 200                 205             


Ile Met Glu Leu Pro Thr Tyr Thr Gly Ser Ile Tyr Pro Thr Val Lys 
    210                 215                 220                 


Pro Tyr His Tyr Pro Lys Ala Gly Ser Glu Asn Pro Ser Ile Ser Leu 
225                 230                 235                 240 


His Val Ile Gly Leu Asn Gly Pro Thr His Asp Leu Glu Met Met Pro 
                245                 250                 255     


Pro Asp Asp Pro Arg Met Arg Glu Tyr Tyr Ile Thr Met Val Lys Trp 
            260                 265                 270         


Ala Thr Ser Thr Lys Val Ala Val Thr Trp Leu Asn Arg Ala Gln Asn 
        275                 280                 285             


Val Ser Ile Leu Thr Leu Cys Asp Ala Thr Thr Gly Val Cys Thr Lys 
    290                 295                 300                 


Lys His Glu Asp Glu Ser Glu Ala Trp Leu His Arg Gln Asn Glu Glu 
305                 310                 315                 320 


Pro Val Phe Ser Lys Asp Gly Arg Lys Phe Phe Phe Ile Arg Ala Ile 
                325                 330                 335     


Pro Gln Gly Gly Arg Gly Lys Phe Tyr His Ile Thr Val Ser Ser Ser 
            340                 345                 350         


Gln Pro Asn Ser Ser Asn Asp Asn Ile Gln Ser Ile Thr Ser Gly Asp 
        355                 360                 365             


Trp Asp Val Thr Lys Ile Leu Ala Tyr Asp Glu Lys Gly Asn Lys Ile 
    370                 375                 380                 


Tyr Phe Leu Ser Thr Glu Asp Leu Pro Arg Arg Arg Gln Leu Tyr Ser 
385                 390                 395                 400 


Ala Asn Thr Val Gly Asn Phe Asn Arg Gln Cys Leu Ser Cys Asp Leu 
                405                 410                 415     


Val Glu Asn Cys Thr Tyr Phe Ser Ala Ser Phe Ser His Ser Met Asp 
            420                 425                 430         


Phe Phe Leu Leu Lys Cys Glu Gly Pro Gly Val Pro Met Val Thr Val 
        435                 440                 445             


His Asn Thr Thr Asp Lys Lys Lys Met Phe Asp Leu Glu Thr Asn Glu 
    450                 455                 460                 


His Val Lys Lys Ala Ile Asn Asp Arg Gln Met Pro Lys Val Glu Tyr 
465                 470                 475                 480 


Arg Asp Ile Glu Ile Asp Asp Tyr Asn Leu Pro Met Gln Ile Leu Lys 
                485                 490                 495     


Pro Ala Thr Phe Thr Asp Thr Thr His Tyr Pro Leu Leu Leu Val Val 
            500                 505                 510         


Asp Gly Thr Pro Gly Ser Gln Ser Val Ala Glu Lys Phe Glu Val Ser 
        515                 520                 525             


Trp Glu Thr Val Met Val Ser Ser His Gly Ala Val Val Val Lys Cys 
    530                 535                 540                 


Glu Gly Arg Gly Ser Gly Phe Arg Gly Thr Lys Leu Leu His Glu Val 
545                 550                 555                 560 


Arg Arg Arg Leu Gly Leu Leu Glu Glu Lys Asp Gln Met Glu Ala Val 
                565                 570                 575     


Arg Thr Met Leu Lys Glu Gln Tyr Ile Asp Arg Thr Arg Val Ala Val 
            580                 585                 590         


Phe Gly Lys Asp Tyr Gly Gly Tyr Leu Ser Thr Tyr Ile Leu Pro Ala 
        595                 600                 605             


Lys Gly Glu Asn Gln Gly Gln Thr Phe Thr Cys Gly Ser Ala Leu Ser 
    610                 615                 620                 


Pro Ile Thr Asp Phe Lys Leu Tyr Ala Ser Ala Phe Ser Glu Arg Tyr 
625                 630                 635                 640 


Leu Gly Leu His Gly Leu Asp Asn Arg Ala Tyr Glu Met Thr Lys Val 
                645                 650                 655     


Ala His Arg Val Ser Ala Leu Glu Glu Gln Gln Phe Leu Ile Ile His 
            660                 665                 670         


Pro Thr Ala Asp Glu Lys Ile His Phe Gln His Thr Ala Glu Leu Ile 
        675                 680                 685             


Thr Gln Leu Ile Arg Gly Lys Ala Asn Tyr Ser Leu Gln Ile Tyr Pro 
    690                 695                 700                 


Asp Glu Ser His Tyr Phe Thr Ser Ser Ser Leu Lys Gln His Leu Tyr 
705                 710                 715                 720 


Arg Ser Ile Ile Asn Phe Phe Val Glu Cys Phe Arg Ile Gln Asp Lys 
                725                 730                 735     


Leu Leu Thr Val Thr Ala Lys Glu Asp Glu Glu Glu Asp 
            740                 745                 


<210>  2228
<211>  451
<212>  PRT
<213>  Homo Sapiens

<400>  2228

Lys Asn Tyr Ser Val Leu Tyr Phe Gln Gln Lys Val Asp His Phe Gly 
1               5                   10                  15      


Phe Asn Thr Val Lys Thr Phe Asn Gln Arg Tyr Leu Val Ala Asp Lys 
            20                  25                  30          


Tyr Trp Lys Lys Asn Gly Gly Ser Ile Leu Phe Tyr Thr Gly Asn Glu 
        35                  40                  45              


Gly Asp Ile Ile Trp Phe Cys Asn Asn Thr Gly Phe Met Trp Asp Val 
    50                  55                  60                  


Ala Glu Glu Leu Lys Ala Met Leu Val Phe Ala Glu His Arg Tyr Tyr 
65                  70                  75                  80  


Gly Glu Ser Leu Pro Phe Gly Asp Asn Ser Phe Lys Asp Ser Arg His 
                85                  90                  95      


Leu Asn Phe Leu Thr Ser Glu Gln Ala Leu Ala Asp Phe Ala Glu Leu 
            100                 105                 110         


Ile Lys His Leu Lys Arg Thr Ile Pro Gly Ala Glu Asn Gln Pro Val 
        115                 120                 125             


Ile Ala Ile Gly Gly Ser Tyr Gly Gly Met Leu Ala Ala Trp Phe Arg 
    130                 135                 140                 


Met Lys Tyr Pro His Met Val Val Gly Ala Leu Ala Ala Ser Ala Pro 
145                 150                 155                 160 


Ile Trp Gln Phe Glu Asp Leu Val Pro Cys Gly Val Phe Met Lys Ile 
                165                 170                 175     


Val Thr Thr Asp Phe Arg Lys Ser Gly Pro His Cys Ser Glu Ser Ile 
            180                 185                 190         


His Arg Ser Trp Asp Ala Ile Asn Arg Leu Ser Asn Thr Gly Ser Gly 
        195                 200                 205             


Leu Gln Trp Leu Thr Gly Ala Leu His Leu Cys Ser Pro Leu Thr Ser 
    210                 215                 220                 


Gln Asp Ile Gln His Leu Lys Asp Trp Ile Ser Glu Thr Trp Val Asn 
225                 230                 235                 240 


Leu Ala Met Val Asp Tyr Pro Tyr Ala Ser Asn Phe Leu Gln Pro Leu 
                245                 250                 255     


Pro Ala Trp Pro Ile Lys Val Val Cys Gln Tyr Leu Lys Asn Pro Asn 
            260                 265                 270         


Val Ser Asp Ser Leu Leu Leu Gln Asn Ile Phe Gln Ala Leu Asn Val 
        275                 280                 285             


Tyr Tyr Asn Tyr Ser Gly Gln Val Lys Cys Leu Asn Ile Ser Glu Thr 
    290                 295                 300                 


Ala Thr Ser Ser Leu Gly Thr Leu Gly Trp Ser Tyr Gln Ala Cys Thr 
305                 310                 315                 320 


Glu Val Val Met Pro Phe Cys Thr Asn Gly Val Asp Asp Met Phe Glu 
                325                 330                 335     


Pro His Ser Trp Asn Leu Lys Glu Leu Ser Asp Asp Cys Phe Gln Gln 
            340                 345                 350         


Trp Gly Val Arg Pro Arg Pro Ser Trp Ile Thr Thr Met Tyr Gly Gly 
        355                 360                 365             


Lys Asn Ile Ser Ser His Thr Asn Ile Val Phe Ser Asn Gly Glu Leu 
    370                 375                 380                 


Asp Pro Trp Ser Gly Gly Gly Val Thr Lys Asp Ile Thr Asp Thr Leu 
385                 390                 395                 400 


Val Ala Val Thr Ile Ser Glu Gly Ala His His Leu Asp Leu Arg Thr 
                405                 410                 415     


Lys Asn Ala Leu Asp Pro Met Ser Val Leu Leu Ala Arg Ser Leu Glu 
            420                 425                 430         


Val Arg His Met Lys Asn Trp Ile Arg Asp Phe Tyr Asp Ser Ala Gly 
        435                 440                 445             


Lys Gln His 
    450     


<210>  2229
<211>  681
<212>  PRT
<213>  Homo Sapiens

<400>  2229

Gln Tyr Gln Thr Arg Ser Pro Ser Val Cys Leu Ser Glu Ala Cys Val 
1               5                   10                  15      


Ser Val Thr Ser Ser Ile Leu Ser Ser Met Asp Pro Thr Val Asp Pro 
            20                  25                  30          


Cys His Asp Phe Phe Ser Tyr Ala Cys Gly Gly Trp Ile Lys Ala Asn 
        35                  40                  45              


Pro Val Pro Asp Gly His Ser Arg Trp Gly Thr Phe Ser Asn Leu Trp 
    50                  55                  60                  


Glu His Asn Gln Ala Ile Ile Lys His Leu Leu Glu Asn Ser Thr Ala 
65                  70                  75                  80  


Ser Val Ser Glu Ala Glu Arg Lys Ala Gln Val Tyr Tyr Arg Ala Cys 
                85                  90                  95      


Met Asn Glu Thr Arg Ile Glu Glu Leu Arg Ala Lys Pro Leu Met Glu 
            100                 105                 110         


Leu Ile Glu Arg Leu Gly Gly Trp Asn Ile Thr Gly Pro Trp Ala Lys 
        115                 120                 125             


Asp Asn Phe Gln Asp Thr Leu Gln Val Val Thr Ala His Tyr Arg Thr 
    130                 135                 140                 


Ser Pro Phe Phe Ser Val Tyr Val Ser Ala Asp Ser Lys Asn Ser Asn 
145                 150                 155                 160 


Ser Asn Val Ile Gln Val Asp Gln Ser Gly Leu Gly Leu Pro Ser Arg 
                165                 170                 175     


Asp Tyr Tyr Leu Asn Lys Thr Glu Asn Glu Lys Val Leu Thr Gly Tyr 
            180                 185                 190         


Leu Asn Tyr Met Val Gln Leu Gly Lys Leu Leu Gly Gly Gly Asp Glu 
        195                 200                 205             


Glu Ala Ile Arg Pro Gln Met Gln Gln Ile Leu Asp Phe Glu Thr Ala 
    210                 215                 220                 


Leu Ala Asn Ile Thr Ile Pro Gln Glu Lys Arg Arg Asp Glu Glu Leu 
225                 230                 235                 240 


Ile Tyr His Lys Val Thr Ala Ala Glu Leu Gln Thr Leu Ala Pro Ala 
                245                 250                 255     


Ile Asn Trp Leu Pro Phe Leu Asn Thr Ile Phe Tyr Pro Val Glu Ile 
            260                 265                 270         


Asn Glu Ser Glu Pro Ile Val Val Tyr Asp Lys Glu Tyr Leu Glu Gln 
        275                 280                 285             


Ile Ser Thr Leu Ile Asn Thr Thr Asp Arg Cys Leu Leu Asn Asn Tyr 
    290                 295                 300                 


Met Ile Trp Asn Leu Val Arg Lys Thr Ser Ser Phe Leu Asp Gln Arg 
305                 310                 315                 320 


Phe Gln Asp Ala Asp Glu Lys Phe Met Glu Val Met Tyr Gly Thr Lys 
                325                 330                 335     


Lys Thr Cys Leu Pro Arg Trp Lys Phe Cys Val Ser Asp Thr Glu Asn 
            340                 345                 350         


Asn Leu Gly Phe Ala Leu Gly Pro Met Phe Val Lys Ala Thr Phe Ala 
        355                 360                 365             


Glu Asp Ser Lys Ser Ile Ala Thr Glu Ile Ile Leu Glu Ile Lys Lys 
    370                 375                 380                 


Ala Phe Glu Glu Ser Leu Ser Thr Leu Lys Trp Met Asp Glu Glu Thr 
385                 390                 395                 400 


Arg Lys Ser Ala Lys Glu Lys Ala Asp Ala Ile Tyr Asn Met Ile Gly 
                405                 410                 415     


Tyr Pro Asn Phe Ile Met Asp Pro Lys Glu Leu Asp Lys Val Phe Asn 
            420                 425                 430         


Asp Tyr Thr Ala Val Pro Asp Leu Tyr Phe Glu Asn Ala Met Arg Phe 
        435                 440                 445             


Phe Asn Phe Ser Trp Arg Val Thr Ala Asp Gln Leu Arg Lys Ala Pro 
    450                 455                 460                 


Asn Arg Asp Gln Trp Ser Met Thr Pro Pro Met Val Asn Ala Tyr Tyr 
465                 470                 475                 480 


Ser Pro Thr Lys Asn Glu Ile Val Phe Pro Ala Gly Ile Leu Gln Ala 
                485                 490                 495     


Pro Phe Tyr Thr Arg Ser Ser Pro Lys Ala Leu Asn Phe Gly Gly Ile 
            500                 505                 510         


Gly Val Val Val Gly His Glu Leu Thr His Ala Phe Asp Asp Gln Gly 
        515                 520                 525             


Arg Glu Tyr Asp Lys Asp Gly Asn Leu Arg Pro Trp Trp Lys Asn Ser 
    530                 535                 540                 


Ser Val Glu Ala Phe Lys Arg Gln Thr Glu Cys Met Val Glu Gln Tyr 
545                 550                 555                 560 


Ser Asn Tyr Ser Val Asn Gly Glu Pro Val Asn Gly Arg His Thr Leu 
                565                 570                 575     


Gly Glu Asn Ile Ala Asp Asn Gly Gly Leu Lys Ala Ala Tyr Arg Ala 
            580                 585                 590         


Tyr Gln Asn Trp Val Lys Lys Asn Gly Ala Glu His Ser Leu Pro Thr 
        595                 600                 605             


Leu Gly Leu Thr Asn Asn Gln Leu Phe Phe Leu Gly Phe Ala Gln Val 
    610                 615                 620                 


Trp Cys Ser Val Arg Thr Pro Glu Ser Ser His Glu Gly Leu Ile Thr 
625                 630                 635                 640 


Asp Pro His Ser Pro Ser Arg Phe Arg Val Ile Gly Ser Leu Ser Asn 
                645                 650                 655     


Ser Lys Glu Phe Ser Glu His Phe Arg Cys Pro Pro Gly Ser Pro Met 
            660                 665                 670         


Asn Pro Pro His Lys Cys Glu Val Trp 
        675                 680     


<210>  2230
<211>  91
<212>  PRT
<213>  Homo Sapiens

<400>  2230

Ser Ile Lys Pro Gly Val Thr Gln Lys Val Gly Glu Ile Ala Arg Thr 
1               5                   10                  15      


Gly Ser Thr Pro Glu Val Ser Thr Val Asp Ala Met Leu Asp Leu Ile 
            20                  25                  30          


Arg Asn Met Phe Pro Glu Asn Leu Val Gln Ala Cys Phe Gln Gln Tyr 
        35                  40                  45              


Lys Thr Lys Arg Glu Glu Val Lys Pro Pro Ser Asp Pro Glu Met Asn 
    50                  55                  60                  


Met Thr Glu Glu Ser Phe Thr Ala Val Met Thr Thr Ala Ile Ser Lys 
65                  70                  75                  80  


Asn Lys Thr Lys Glu Tyr Lys Ile Val Gly Met 
                85                  90      


<210>  2231
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2231

Lys Pro Gly Ser Gly Ala Gln Thr Leu Gln Ser Ser Asp Leu Gly Leu 
1               5                   10                  15      


Glu Asp Ser Gly Pro Pro Pro Val Pro Lys Glu Thr Val Asp Ser Phe 
            20                  25                  30          


Leu Asp Leu Ala Arg Asn Leu Phe Pro Ser Asn Leu Val Val Ala Ala 
        35                  40                  45              


Phe Arg Thr Tyr Ala Thr Asp Tyr Lys Val Val Thr Gln Asn Ser Ser 
    50                  55                  60                  


Ser Gly Asn Val Thr His Glu Lys Ile Pro Ile Gly Thr 
65                  70                  75          


<210>  2232
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  2232

Leu Pro Leu Arg Phe Asp Trp Arg Asp Lys Gln Val Val Thr Gln Val 
1               5                   10                  15      


Arg Asn Gln Gln Met Cys Gly Gly Cys Trp Ala Phe Ser Val Val Gly 
            20                  25                  30          


Ala Val Glu Ser Ala Tyr Ala Ile Lys Gly Lys Pro Leu Glu Asp Leu 
        35                  40                  45              


Ser Val Gln Gln Val Ile Asp Cys Ser Tyr Asn Asn Tyr Gly Cys Asn 
    50                  55                  60                  


Gly Gly Ser Thr Leu Asn Ala Leu Asn Trp Leu Asn Lys Met Gln Val 
65                  70                  75                  80  


Lys Leu Val Lys Asp Ser Glu Tyr Pro Phe Lys Ala Gln Asn Gly Leu 
                85                  90                  95      


Cys His Tyr Phe Ser Gly Ser His Ser Gly Phe Ser Ile Lys Gly Tyr 
            100                 105                 110         


Ser Ala Tyr Asp Phe Ser Asp Gln Glu Asp Glu Met Ala Lys Ala Leu 
        115                 120                 125             


Leu Thr Phe Gly Pro Leu Val Val Ile Val Asp Ala Val Ser Trp Gln 
    130                 135                 140                 


Asp Tyr Leu Gly Gly Ile Ile Gln His His Cys Ser Ser Gly Glu Ala 
145                 150                 155                 160 


Asn His Ala Val Leu Ile Thr Gly Phe Asp Lys Thr Gly Ser Thr Pro 
                165                 170                 175     


Tyr Trp Ile Val Arg Asn Ser Trp Gly Ser Ser Trp Gly Val Asp Gly 
            180                 185                 190         


Tyr Ala His Val Lys Met Gly Ser Asn Val Cys Gly Ile Ala Asp Ser 
        195                 200                 205             


Val Ser Ser Ile Phe Val 
    210                 


<210>  2233
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  2233

Ala Pro Asp Ser Val Asp Tyr Arg Lys Lys Gly Tyr Val Thr Pro Val 
1               5                   10                  15      


Lys Asn Gln Gly Gln Cys Gly Ser Cys Trp Ala Phe Ser Ser Val Gly 
            20                  25                  30          


Ala Leu Glu Gly Gln Leu Lys Lys Lys Thr Gly Lys Leu Leu Asn Leu 
        35                  40                  45              


Ser Pro Gln Asn Leu Val Asp Cys Val Ser Glu Asn Asp Gly Cys Gly 
    50                  55                  60                  


Gly Gly Tyr Met Thr Asn Ala Phe Gln Tyr Val Gln Lys Asn Arg Gly 
65                  70                  75                  80  


Ile Asp Ser Glu Asp Ala Tyr Pro Tyr Val Gly Gln Glu Glu Ser Cys 
                85                  90                  95      


Met Tyr Asn Pro Thr Gly Lys Ala Ala Lys Cys Arg Gly Tyr Arg Glu 
            100                 105                 110         


Ile Pro Glu Gly Asn Glu Lys Ala Leu Lys Arg Ala Val Ala Arg Val 
        115                 120                 125             


Gly Pro Val Ser Val Ala Ile Asp Ala Ser Leu Thr Ser Phe Gln Phe 
    130                 135                 140                 


Tyr Ser Lys Gly Val Tyr Tyr Asp Glu Ser Cys Asn Ser Asp Asn Leu 
145                 150                 155                 160 


Asn His Ala Val Leu Ala Val Gly Tyr Gly Ile Gln Lys Gly Asn Lys 
                165                 170                 175     


His Trp Ile Ile Lys Asn Ser Trp Gly Glu Asn Trp Gly Asn Lys Gly 
            180                 185                 190         


Tyr Ile Leu Met Ala Arg Asn Lys Asn Asn Ala Cys Gly Ile Ala Asn 
        195                 200                 205             


Leu Ala Ser Phe Pro Lys Met 
    210                 215 


<210>  2234
<211>  502
<212>  PRT
<213>  Homo Sapiens

<400>  2234

Ala His Thr Gly Glu Glu Ser Val Ala Asp His His Glu Ala Glu Tyr 
1               5                   10                  15      


Tyr Val Ala Ala Val Tyr Glu His Pro Ser Ile Leu Ser Leu Asn Pro 
            20                  25                  30          


Leu Ala Leu Ile Ser Arg Gln Glu Ala Leu Glu Leu Met Asn Gln Asn 
        35                  40                  45              


Leu Asp Ile Tyr Glu Gln Gln Val Met Thr Ala Ala Gln Lys Asp Val 
    50                  55                  60                  


Gln Ile Ile Val Phe Pro Glu Asp Gly Ile His Gly Phe Asn Phe Thr 
65                  70                  75                  80  


Arg Thr Ser Ile Tyr Pro Phe Leu Asp Phe Met Pro Ser Pro Gln Val 
                85                  90                  95      


Val Arg Trp Asn Pro Cys Leu Glu Pro His Arg Phe Asn Asp Thr Glu 
            100                 105                 110         


Val Leu Gln Arg Leu Ser Cys Met Ala Ile Arg Gly Asp Met Phe Leu 
        115                 120                 125             


Val Ala Asn Leu Gly Thr Lys Glu Pro Cys His Ser Ser Asp Pro Arg 
    130                 135                 140                 


Cys Pro Lys Asp Gly Arg Tyr Gln Phe Asn Thr Asn Val Val Phe Ser 
145                 150                 155                 160 


Asn Asn Gly Thr Leu Val Asp Arg Tyr Arg Lys His Asn Leu Tyr Phe 
                165                 170                 175     


Glu Ala Ala Phe Asp Val Pro Leu Lys Val Asp Leu Ile Thr Phe Asp 
            180                 185                 190         


Thr Pro Phe Ala Gly Arg Phe Gly Ile Phe Thr Cys Phe Asp Ile Leu 
        195                 200                 205             


Phe Phe Asp Pro Ala Ile Arg Val Leu Arg Asp Tyr Lys Val Lys His 
    210                 215                 220                 


Val Val Tyr Pro Thr Ala Trp Met Asn Gln Leu Pro Leu Leu Ala Ala 
225                 230                 235                 240 


Ile Glu Ile Gln Lys Ala Phe Ala Val Ala Phe Gly Ile Asn Val Leu 
                245                 250                 255     


Ala Ala Asn Val His His Pro Val Leu Gly Met Thr Gly Ser Gly Ile 
            260                 265                 270         


His Thr Pro Leu Glu Ser Phe Trp Tyr His Asp Met Glu Asn Pro Lys 
        275                 280                 285             


Ser His Leu Ile Ile Ala Gln Val Ala Lys Asn Pro Val Gly Leu Ile 
    290                 295                 300                 


Gly Ala Glu Asn Ala Thr Gly Glu Thr Asp Pro Ser His Ser Lys Phe 
305                 310                 315                 320 


Leu Lys Ile Leu Ser Gly Asp Pro Tyr Cys Glu Lys Asp Ala Gln Glu 
                325                 330                 335     


Val His Cys Asp Glu Ala Thr Lys Trp Asn Val Asn Ala Pro Pro Thr 
            340                 345                 350         


Phe His Ser Glu Met Met Tyr Asp Asn Phe Thr Leu Val Pro Val Trp 
        355                 360                 365             


Gly Lys Glu Gly Tyr Leu His Val Cys Ser Asn Gly Leu Cys Cys Tyr 
    370                 375                 380                 


Leu Leu Tyr Glu Arg Pro Thr Leu Ser Lys Glu Leu Tyr Ala Leu Gly 
385                 390                 395                 400 


Val Phe Asp Gly Leu His Thr Val His Gly Thr Tyr Tyr Ile Gln Val 
                405                 410                 415     


Cys Ala Leu Val Arg Cys Gly Gly Leu Gly Phe Asp Thr Cys Gly Gln 
            420                 425                 430         


Glu Ile Thr Glu Ala Thr Gly Ile Phe Glu Phe His Leu Trp Gly Asn 
        435                 440                 445             


Phe Ser Thr Ser Tyr Ile Phe Pro Leu Phe Leu Thr Ser Gly Met Thr 
    450                 455                 460                 


Leu Glu Val Pro Asp Gln Leu Gly Trp Glu Asn Asp His Tyr Phe Leu 
465                 470                 475                 480 


Arg Lys Ser Arg Leu Ser Ser Gly Leu Val Thr Ala Ala Leu Tyr Gly 
                485                 490                 495     


Arg Leu Tyr Glu Arg Asp 
            500         


<210>  2235
<211>  491
<212>  PRT
<213>  Homo Sapiens

<400>  2235

Met Asn Pro Ala Ala Glu Ala Glu Phe Asn Ile Leu Leu Ala Thr Asp 
1               5                   10                  15      


Ser Tyr Lys Val Thr His Tyr Lys Gln Tyr Pro Pro Asn Thr Ser Lys 
            20                  25                  30          


Val Tyr Ser Tyr Phe Glu Cys Arg Glu Lys Lys Thr Glu Asn Ser Lys 
        35                  40                  45              


Leu Arg Lys Val Lys Tyr Glu Glu Thr Val Phe Tyr Gly Leu Gln Tyr 
    50                  55                  60                  


Ile Leu Asn Lys Tyr Leu Lys Gly Lys Val Val Thr Lys Glu Lys Ile 
65                  70                  75                  80  


Gln Glu Ala Lys Asp Val Tyr Lys Glu His Phe Gln Asp Asp Val Phe 
                85                  90                  95      


Asn Glu Lys Gly Trp Asn Tyr Ile Leu Glu Lys Tyr Asp Gly His Leu 
            100                 105                 110         


Pro Ile Glu Ile Lys Ala Val Pro Glu Gly Phe Val Ile Pro Arg Gly 
        115                 120                 125             


Asn Val Leu Phe Thr Val Glu Asn Thr Asp Pro Glu Cys Tyr Trp Leu 
    130                 135                 140                 


Thr Asn Trp Ile Glu Thr Ile Leu Val Gln Ser Trp Tyr Pro Ile Thr 
145                 150                 155                 160 


Val Ala Thr Asn Ser Arg Glu Gln Lys Lys Ile Leu Ala Lys Tyr Leu 
                165                 170                 175     


Leu Glu Thr Ser Gly Asn Leu Asp Gly Leu Glu Tyr Lys Leu His Asp 
            180                 185                 190         


Phe Gly Tyr Arg Gly Val Ser Ser Gln Glu Thr Ala Gly Ile Gly Ala 
        195                 200                 205             


Ser Ala His Leu Val Asn Phe Lys Gly Thr Asp Thr Val Ala Gly Leu 
    210                 215                 220                 


Ala Leu Ile Lys Lys Tyr Tyr Gly Thr Lys Asp Pro Val Pro Gly Tyr 
225                 230                 235                 240 


Ser Val Pro Ala Ala Glu His Ser Thr Ile Thr Ala Trp Gly Lys Asp 
                245                 250                 255     


His Glu Lys Asp Ala Phe Glu His Ile Val Thr Gln Phe Ser Ser Val 
            260                 265                 270         


Pro Val Ser Val Val Ser Asp Ser Tyr Asp Ile Tyr Asn Ala Cys Glu 
        275                 280                 285             


Lys Ile Trp Gly Glu Asp Leu Arg His Leu Ile Val Ser Arg Ser Thr 
    290                 295                 300                 


Gln Ala Pro Leu Ile Ile Arg Pro Asp Ser Gly Asn Pro Leu Asp Thr 
305                 310                 315                 320 


Val Leu Lys Val Leu Glu Ile Leu Gly Lys Lys Phe Pro Val Thr Glu 
                325                 330                 335     


Asn Ser Lys Gly Tyr Lys Leu Leu Pro Pro Tyr Leu Arg Val Ile Gln 
            340                 345                 350         


Gly Asp Gly Val Asp Ile Asn Thr Leu Gln Glu Ile Val Glu Gly Met 
        355                 360                 365             


Lys Gln Lys Met Trp Ser Ile Glu Asn Ile Ala Phe Gly Ser Gly Gly 
    370                 375                 380                 


Gly Leu Leu Gln Lys Leu Thr Arg Asp Leu Leu Asn Cys Ser Phe Lys 
385                 390                 395                 400 


Cys Ser Tyr Val Val Thr Asn Gly Leu Gly Ile Asn Val Phe Lys Asp 
                405                 410                 415     


Pro Val Ala Asp Pro Asn Lys Arg Ser Lys Lys Gly Arg Leu Ser Leu 
            420                 425                 430         


His Arg Thr Pro Ala Gly Asn Phe Val Thr Leu Glu Glu Gly Lys Gly 
        435                 440                 445             


Asp Leu Glu Glu Tyr Gly Gln Asp Leu Leu His Thr Val Phe Lys Asn 
    450                 455                 460                 


Gly Lys Val Thr Lys Ser Tyr Ser Phe Asp Glu Ile Arg Lys Asn Ala 
465                 470                 475                 480 


Gln Leu Asn Ile Glu Leu Glu Ala Ala His His 
                485                 490     


<210>  2236
<211>  578
<212>  PRT
<213>  Homo Sapiens

<400>  2236

Leu Pro Thr Gln Pro Arg Asp Ile Glu Asn Phe Asn Ser Thr Gln Lys 
1               5                   10                  15      


Phe Ile Glu Asp Asn Ile Glu Tyr Ile Thr Ile Ile Ala Phe Ala Gln 
            20                  25                  30          


Tyr Val Gln Glu Ala Thr Phe Glu Glu Met Glu Lys Leu Val Lys Asp 
        35                  40                  45              


Met Val Glu Tyr Lys Asp Arg Cys Met Ala Asp Lys Thr Leu Pro Glu 
    50                  55                  60                  


Cys Ser Lys Leu Pro Asn Asn Val Leu Gln Glu Lys Ile Cys Ala Met 
65                  70                  75                  80  


Glu Gly Leu Pro Gln Lys His Asn Phe Ser His Cys Cys Ser Lys Val 
                85                  90                  95      


Asp Ala Gln Arg Arg Leu Cys Phe Phe Tyr Asn Lys Lys Ser Asp Val 
            100                 105                 110         


Gly Phe Leu Pro Pro Phe Pro Thr Leu Asp Pro Glu Glu Lys Cys Gln 
        115                 120                 125             


Ala Tyr Glu Ser Asn Arg Glu Ser Leu Leu Asn His Phe Leu Tyr Glu 
    130                 135                 140                 


Val Ala Arg Arg Asn Pro Phe Val Phe Ala Pro Thr Leu Leu Thr Val 
145                 150                 155                 160 


Ala Val His Phe Glu Glu Val Ala Lys Ser Cys Cys Glu Glu Gln Asn 
                165                 170                 175     


Lys Val Asn Cys Leu Gln Thr Arg Ala Ile Pro Val Thr Gln Tyr Leu 
            180                 185                 190         


Lys Ala Phe Ser Ser Tyr Gln Lys His Val Cys Gly Ala Leu Leu Lys 
        195                 200                 205             


Phe Gly Thr Lys Val Val His Phe Ile Tyr Ile Ala Ile Leu Ser Gln 
    210                 215                 220                 


Lys Phe Pro Lys Ile Glu Phe Lys Glu Leu Ile Ser Leu Val Glu Asp 
225                 230                 235                 240 


Val Ser Ser Asn Tyr Asp Gly Cys Cys Glu Gly Asp Val Val Gln Cys 
                245                 250                 255     


Ile Arg Asp Thr Ser Lys Val Met Asn His Ile Cys Ser Lys Gln Asp 
            260                 265                 270         


Ser Ile Ser Ser Lys Ile Lys Glu Cys Cys Glu Lys Lys Ile Pro Glu 
        275                 280                 285             


Arg Gly Gln Cys Ile Ile Asn Ser Asn Lys Asp Asp Arg Pro Lys Asp 
    290                 295                 300                 


Leu Ser Leu Arg Glu Gly Lys Phe Thr Asp Ser Glu Asn Val Cys Gln 
305                 310                 315                 320 


Glu Arg Asp Ala Asp Pro Asp Thr Phe Phe Ala Lys Phe Thr Phe Glu 
                325                 330                 335     


Tyr Ser Arg Arg His Pro Asp Leu Ser Ile Pro Glu Leu Leu Arg Ile 
            340                 345                 350         


Val Gln Ile Tyr Lys Asp Leu Leu Arg Asn Cys Cys Asn Thr Glu Asn 
        355                 360                 365             


Pro Pro Gly Cys Tyr Arg Tyr Ala Glu Asp Lys Phe Asn Glu Thr Thr 
    370                 375                 380                 


Glu Lys Ser Leu Lys Met Val Gln Gln Glu Cys Lys His Phe Gln Asn 
385                 390                 395                 400 


Leu Gly Lys Asp Gly Leu Lys Tyr His Tyr Leu Ile Arg Leu Thr Lys 
                405                 410                 415     


Ile Ala Pro Gln Leu Ser Thr Glu Glu Leu Val Ser Leu Gly Glu Lys 
            420                 425                 430         


Met Val Thr Ala Phe Thr Thr Cys Cys Thr Leu Ser Glu Glu Phe Ala 
        435                 440                 445             


Cys Val Asp Asn Leu Ala Asp Leu Val Phe Gly Glu Leu Cys Gly Val 
    450                 455                 460                 


Asn Glu Asn Arg Thr Ile Asn Pro Ala Val Asp His Cys Cys Lys Thr 
465                 470                 475                 480 


Asn Phe Ala Phe Arg Arg Pro Cys Phe Glu Ser Leu Lys Ala Asp Lys 
                485                 490                 495     


Thr Tyr Val Pro Pro Pro Phe Ser Gln Asp Leu Phe Thr Phe His Ala 
            500                 505                 510         


Asp Met Cys Gln Ser Gln Asn Glu Glu Leu Gln Arg Lys Thr Asp Arg 
        515                 520                 525             


Phe Leu Val Asn Leu Val Lys Leu Lys His Glu Leu Thr Asp Glu Glu 
    530                 535                 540                 


Leu Gln Ser Leu Phe Thr Asn Phe Ala Asn Val Val Asp Lys Cys Cys 
545                 550                 555                 560 


Lys Ala Glu Ser Pro Glu Val Cys Phe Asn Glu Glu Ser Pro Lys Ile 
                565                 570                 575     


Gly Asn 
        


<210>  2237
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  2237

His Val Glu Thr Arg Ala His Ala Glu Glu Arg Leu Leu Lys Lys Leu 
1               5                   10                  15      


Phe Ser Gly Tyr Asn Lys Trp Ser Arg Pro Val Ala Asn Ile Ser Asp 
            20                  25                  30          


Val Val Leu Val Arg Phe Gly Leu Ser Ile Ala Gln Leu Ile Asp Val 
        35                  40                  45              


Asp Glu Lys Asn Gln Met Met Thr Thr Asn Val Trp Val Lys Gln Glu 
    50                  55                  60                  


Trp His Asp Tyr Lys Leu Arg Trp Asp Pro Ala Asp Tyr Glu Asn Val 
65                  70                  75                  80  


Thr Ser Ile Arg Ile Pro Ser Glu Leu Ile Trp Arg Pro Asp Ile Val 
                85                  90                  95      


Leu Tyr Asn Asn Ala Asp Gly Asp Phe Ala Val Thr His Leu Thr Lys 
            100                 105                 110         


Ala His Leu Phe His Asp Gly Arg Val Gln Trp Thr Pro Pro Ala Ile 
        115                 120                 125             


Tyr Lys Ser Ser Cys Ser Ile Asp Val Thr Phe Phe Pro Phe Asp Gln 
    130                 135                 140                 


Gln Asn Cys Thr Met Lys Phe Gly Ser Trp Thr Tyr Asp Lys Ala Lys 
145                 150                 155                 160 


Ile Asp Leu Val Asn Met His Ser Arg Val Asp Gln Leu Asp Phe Trp 
                165                 170                 175     


Glu Ser Gly Glu Trp Val Ile Val Asp Ala Val Gly Thr Tyr Asn Thr 
            180                 185                 190         


Arg Lys Tyr Glu Cys Cys Ala Glu Ile Tyr Pro Asp Ile Thr Tyr Ala 
        195                 200                 205             


Phe Val Ile Arg Arg Leu 
    210                 


<210>  2238
<211>  368
<212>  PRT
<213>  Homo Sapiens

<400>  2238

Tyr Asn Val Phe Pro Arg Thr Leu Lys Trp Ser Lys Met Asn Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Val Asn Tyr Thr Pro Asp Met Thr His Ser Glu Val Glu 
            20                  25                  30          


Lys Ala Phe Lys Lys Ala Phe Lys Val Trp Ser Asp Val Thr Pro Leu 
        35                  40                  45              


Asn Phe Thr Arg Leu His Asp Gly Ile Ala Asp Ile Met Ile Ser Phe 
    50                  55                  60                  


Gly Ile Lys Glu His Gly Asp Phe Tyr Pro Phe Asp Gly Pro Ser Gly 
65                  70                  75                  80  


Leu Leu Ala His Ala Phe Pro Pro Gly Pro Asn Tyr Gly Gly Asp Ala 
                85                  90                  95      


His Phe Asp Asp Asp Glu Thr Trp Thr Ser Ser Ser Lys Gly Tyr Asn 
            100                 105                 110         


Leu Phe Leu Val Ala Ala His Glu Phe Gly His Ser Leu Gly Leu Asp 
        115                 120                 125             


His Ser Lys Asp Pro Gly Ala Leu Met Phe Pro Ile Tyr Thr Tyr Thr 
    130                 135                 140                 


Gly Lys Ser His Phe Met Leu Pro Asp Asp Asp Val Gln Gly Ile Gln 
145                 150                 155                 160 


Ser Leu Tyr Gly Pro Gly Asp Glu Asp Pro Asn Pro Lys His Pro Lys 
                165                 170                 175     


Thr Pro Asp Lys Cys Asp Pro Ser Leu Ser Leu Asp Ala Ile Thr Ser 
            180                 185                 190         


Leu Arg Gly Glu Thr Met Ile Phe Lys Asp Arg Phe Phe Trp Arg Leu 
        195                 200                 205             


His Pro Gln Gln Val Asp Ala Glu Leu Phe Leu Thr Lys Ser Phe Trp 
    210                 215                 220                 


Pro Glu Leu Pro Asn Arg Ile Asp Ala Ala Tyr Glu His Pro Ser His 
225                 230                 235                 240 


Asp Leu Ile Phe Ile Phe Arg Gly Arg Lys Phe Trp Ala Leu Asn Gly 
                245                 250                 255     


Tyr Asp Ile Leu Glu Gly Tyr Pro Lys Lys Ile Ser Glu Leu Gly Leu 
            260                 265                 270         


Pro Lys Glu Val Lys Lys Ile Ser Ala Ala Val His Phe Glu Asp Thr 
        275                 280                 285             


Gly Lys Thr Leu Leu Phe Ser Gly Asn Gln Val Trp Arg Tyr Asp Asp 
    290                 295                 300                 


Thr Asn His Ile Met Asp Lys Asp Tyr Pro Arg Leu Ile Glu Glu Asp 
305                 310                 315                 320 


Phe Pro Gly Ile Gly Asp Lys Val Asp Ala Val Tyr Glu Lys Asn Gly 
                325                 330                 335     


Tyr Ile Tyr Phe Phe Asn Gly Pro Ile Gln Phe Glu Tyr Ser Ile Trp 
            340                 345                 350         


Ser Asn Arg Ile Val Arg Val Met Pro Ala Asn Ser Ile Leu Trp Cys 
        355                 360                 365             


<210>  2239
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  2239

Asp Thr Ile Pro Thr Tyr Leu Gln Trp Met Ser Tyr Ile Ser Tyr Val 
1               5                   10                  15      


Arg Tyr Gly Phe Glu Gly Val Ile Leu Ser Ile Tyr Gly Leu Asp Arg 
            20                  25                  30          


Glu Asp Leu His Cys Asp Ile Asp Glu Thr Cys His Phe Gln Lys Ser 
        35                  40                  45              


Glu Ala Ile Leu Arg Glu Leu Asp Val Glu Asn Ala Lys Leu Tyr 
    50                  55                  60              


<210>  2240
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  2240

Asp Lys Thr Leu Pro Val Phe Pro Lys Gly Asn Glu Val Gln Ile Lys 
1               5                   10                  15      


Val Leu Asn Ile Gly Asn Asn Thr Met Asn Ile Ser Leu Pro Gly Glu 
            20                  25                  30          


Met Val Thr Leu Gly Pro Met Ser Gln Thr Asn Ala Phe Met Thr Phe 
        35                  40                  45              


Asp Val Asn Lys Leu Thr Arg Ile Asn Ile Ser Ser Pro Gly Ser Pro 
    50                  55                  60                  


Val Thr Ala Val Thr Asp Asp Phe Lys Gln Gly Gln Arg His Thr Leu 
65                  70                  75                  80  


Leu Val Trp Ala Pro Asn His Tyr Gln Val Val Lys Asp Gly Leu Asn 
                85                  90                  95      


Gln Lys Pro Glu Lys Gly Glu Asn Gly Ile Arg Phe Val Asn Thr Phe 
            100                 105                 110         


Asn Glu Leu Ile Thr Ile Thr Met Ser Gly Lys Val Tyr Ala Asn Ile 
        115                 120                 125             


Ser Ser Tyr Asn Ala Ser Thr Tyr Gln Phe Phe Pro Ser Gly Ile Lys 
    130                 135                 140                 


Gly Phe Thr Ile Ser Ser Thr Glu Ile Pro Pro Gln Cys Gln Pro Asn 
145                 150                 155                 160 


Phe Asn Thr Phe Tyr Leu Glu Phe Gly Ser Ala Tyr Thr Tyr Ile Val 
                165                 170                 175     


Gln Arg Lys Asn Asp Ser Cys Pro Glu Val Lys Val Phe Glu Asp Ile 
            180                 185                 190         


Ser Ala Asn Thr Val Asn Met Ala Leu Gln 
        195                 200         


<210>  2241
<211>  218
<212>  PRT
<213>  Homo Sapiens

<400>  2241

Arg Arg Ser Arg Asn Thr Thr Arg Pro Ala Leu Leu Arg Leu Ser Asp 
1               5                   10                  15      


Tyr Leu Leu Thr Asn Tyr Arg Lys Gly Val Arg Pro Val Arg Asp Trp 
            20                  25                  30          


Arg Lys Pro Thr Thr Val Ser Ile Asp Val Ile Val Tyr Ala Ile Leu 
        35                  40                  45              


Asn Val Asp Glu Lys Asn Gln Val Leu Thr Thr Tyr Ile Trp Tyr Arg 
    50                  55                  60                  


Gln Tyr Trp Thr Asp Glu Phe Leu Gln Trp Asn Pro Glu Asp Phe Asp 
65                  70                  75                  80  


Asn Ile Thr Lys Leu Ser Ile Pro Thr Asp Ser Ile Trp Val Pro Asp 
                85                  90                  95      


Ile Leu Ile Asn Glu Phe Val Asp Val Gly Lys Ser Pro Asn Ile Pro 
            100                 105                 110         


Tyr Val Tyr Ile Arg His Gln Gly Glu Val Gln Asn Tyr Lys Pro Leu 
        115                 120                 125             


Gln Val Val Thr Ala Cys Ser Leu Asp Ile Tyr Asn Phe Pro Phe Asp 
    130                 135                 140                 


Val Gln Asn Cys Ser Leu Thr Phe Thr Ser Trp Leu His Thr Ile Gln 
145                 150                 155                 160 


Asp Ile Asn Ile Ser Leu Trp Arg Leu Pro Glu Lys Val Lys Ser Asp 
                165                 170                 175     


Arg Ser Val Phe Met Asn Gln Gly Glu Trp Glu Leu Leu Gly Val Leu 
            180                 185                 190         


Pro Tyr Phe Arg Glu Phe Ser Met Glu Ser Ser Asn Tyr Tyr Ala Glu 
        195                 200                 205             


Met Lys Phe Tyr Val Val Ile Arg Arg Arg 
    210                 215             


<210>  2242
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2242

Met Ala Glu Glu Gly Val Pro Ala Pro Leu Pro Pro Glu Asp Ala Pro 
1               5                   10                  15      


Asn Ala Ala Ser Leu Ala Pro Thr Pro Val Ser Pro Val Leu Glu Pro 
            20                  25                  30          


Phe Asn Leu Thr Ser Glu Pro Ser Asp Tyr Ala Leu Asp Leu Ser Thr 
        35                  40                  45              


Phe Leu Gln Gln His Pro Ala Ala Phe 
    50                  55          


<210>  2243
<211>  170
<212>  PRT
<213>  Homo Sapiens

<400>  2243

Arg Pro Lys Leu Pro Leu Arg Tyr Pro Glu Arg Leu Gln Asn Pro Ser 
1               5                   10                  15      


Glu Ser Ser Glu Pro Ile Pro Leu Glu Ser Arg Glu Glu Tyr Met Asn 
            20                  25                  30          


Gly Met Asn Arg Gln Arg Asn Ile Leu Arg Glu Lys Gln Thr Asp Glu 
        35                  40                  45              


Ile Lys Asp Thr Arg Asn Glu Ser Thr Gln Asn Cys Val Val Ala Glu 
    50                  55                  60                  


Pro Glu Lys Met Glu Ser Ser Ile Ser Ser Ser Ser Glu Glu Met Ser 
65                  70                  75                  80  


Leu Ser Lys Cys Ala Glu Gln Phe Cys Arg Leu Asn Glu Tyr Asn Gln 
                85                  90                  95      


Leu Gln Leu Gln Ala Val His Ala Gln Glu Gln Ile Arg Arg Met Asn 
            100                 105                 110         


Glu Asn Ser His Val Gln Val Pro Phe Gln Gln Leu Asn Gln Leu Ala 
        115                 120                 125             


Ala Tyr Pro Tyr Ala Val Trp Tyr Tyr Pro Gln Ile Met Gln Tyr Val 
    130                 135                 140                 


Pro Phe Pro Pro Phe Ser Asp Ile Ser Asn Pro Thr Ala His Glu Asn 
145                 150                 155                 160 


Tyr Glu Lys Asn Asn Val Met Leu Gln Trp 
                165                 170 


<210>  2244
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  2244

Ser Val Asn Asp Pro Ser Asn Met Ser Leu Val Lys Glu Thr Val Asp 
1               5                   10                  15      


Arg Leu Leu Lys Gly Tyr Asp Ile Arg Leu Arg Pro Asp Phe Gly Gly 
            20                  25                  30          


Pro Pro Val Ala Val Gly Met Asn Ile Asp Ile Ala Ser Ile Asp Met 
        35                  40                  45              


Val Ser Glu Val Asn Met Asp Tyr Thr Leu Thr Met Tyr Phe Gln Gln 
    50                  55                  60                  


Ala Trp Arg Asp Lys Arg Leu Ser Tyr Asn Val Ile Pro Leu Asn Leu 
65                  70                  75                  80  


Thr Leu Asp Asn Arg Val Ala Asp Gln Leu Trp Val Pro Asp Thr Tyr 
                85                  90                  95      


Phe Leu Asn Asp Lys Lys Ser Phe Val His Gly Val Thr Val Lys Asn 
            100                 105                 110         


Arg Met Ile Arg Leu His Pro Asp Gly Thr Val Leu Tyr Gly Leu Arg 
        115                 120                 125             


Ile Thr Thr Thr Ala Ala Cys Met Met Asp Leu Arg Arg Tyr Pro Leu 
    130                 135                 140                 


Asp Glu Gln Asn Cys Thr Leu Glu Ile Glu Ser Tyr Gly Tyr Thr Thr 
145                 150                 155                 160 


Asp Asp Ile Glu Phe Tyr Trp Arg Gly Asp Asp Asn Ala Val Thr Gly 
                165                 170                 175     


Val Thr Lys Ile Glu Leu Pro Gln Phe Ser Ile Val Asp Tyr Lys Leu 
            180                 185                 190         


Ile Thr Lys Lys Val Val Phe Ser Thr Gly Ser Tyr Pro Arg Leu Ser 
        195                 200                 205             


Leu Ser Phe Lys Leu Lys Arg Asn Ile Gly Tyr 
    210                 215                 


<210>  2245
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  2245

Met Ser Asn Val Pro His Lys Ser Ser Leu Pro Glu Gly Ile Arg Pro 
1               5                   10                  15      


Gly Thr Val Leu Arg Ile Arg Gly Leu Val Pro Pro Asn Ala Ser Arg 
            20                  25                  30          


Phe His Val Asn Leu Leu Cys Gly Glu Glu Gln Gly Ser Asp Ala Ala 
        35                  40                  45              


Leu His Phe Asn Pro Arg Leu Asp Thr Ser Glu Val Val Phe Asn Ser 
    50                  55                  60                  


Lys Glu Gln Gly Ser Trp Gly Arg Glu Glu Arg Gly Pro Gly Val Pro 
65                  70                  75                  80  


Phe Gln Arg Gly Gln Pro Phe Glu Val Leu Ile Ile Ala Ser Asp Asp 
                85                  90                  95      


Gly Phe Lys Ala Val Val Gly Asp Ala Gln Tyr His His Phe Arg His 
            100                 105                 110         


Arg Leu Pro Leu Ala Arg Val Arg Leu Val Glu Val Gly Gly Asp Val 
        115                 120                 125             


Gln Leu Asp Ser Val Arg Ile Phe 
    130                 135     


<210>  2246
<211>  416
<212>  PRT
<213>  Homo Sapiens

<400>  2246

Gly Ala Gln Asp Ser Pro Ala Pro Gly Ser Arg Phe Val Cys Thr Ala 
1               5                   10                  15      


Leu Pro Pro Glu Ala Val His Ala Gly Cys Pro Leu Pro Ala Met Pro 
            20                  25                  30          


Met Gln Gly Gly Ala Gln Ser Pro Glu Glu Glu Leu Arg Ala Ala Val 
        35                  40                  45              


Leu Gln Leu Arg Glu Thr Val Val Gln Gln Lys Glu Thr Leu Gly Ala 
    50                  55                  60                  


Gln Arg Glu Ala Ile Arg Glu Leu Thr Gly Lys Leu Ala Arg Cys Glu 
65                  70                  75                  80  


Gly Leu Ala Gly Gly Lys Ala Arg Gly Ala Gly Ala Thr Gly Lys Asp 
                85                  90                  95      


Thr Met Gly Asp Leu Pro Arg Asp Pro Gly His Val Val Glu Gln Leu 
            100                 105                 110         


Ser Arg Ser Leu Gln Thr Leu Lys Asp Arg Leu Glu Ser Leu Glu His 
        115                 120                 125             


Gln Leu Arg Ala Asn Val Ser Asn Ala Gly Leu Pro Gly Asp Phe Arg 
    130                 135                 140                 


Glu Val Leu Gln Gln Arg Leu Gly Glu Leu Glu Arg Gln Leu Leu Arg 
145                 150                 155                 160 


Lys Val Ala Glu Leu Glu Asp Glu Lys Ser Leu Leu His Asn Glu Thr 
                165                 170                 175     


Ser Ala His Arg Gln Lys Thr Glu Ser Thr Leu Asn Ala Leu Leu Gln 
            180                 185                 190         


Arg Val Thr Glu Leu Glu Arg Gly Asn Ser Ala Phe Lys Ser Pro Asp 
        195                 200                 205             


Ala Phe Lys Val Ser Leu Pro Leu Arg Thr Asn Tyr Leu Tyr Gly Lys 
    210                 215                 220                 


Ile Lys Lys Thr Leu Pro Glu Leu Tyr Ala Phe Thr Ile Cys Leu Trp 
225                 230                 235                 240 


Leu Arg Ser Ser Ala Ser Pro Gly Ile Gly Thr Pro Phe Ser Tyr Ala 
                245                 250                 255     


Val Pro Gly Gln Ala Asn Glu Ile Val Leu Ile Glu Trp Gly Asn Asn 
            260                 265                 270         


Pro Ile Glu Leu Leu Ile Asn Asp Lys Val Ala Gln Leu Pro Leu Phe 
        275                 280                 285             


Val Ser Asp Gly Lys Trp His His Ile Cys Val Thr Trp Thr Thr Arg 
    290                 295                 300                 


Asp Gly Met Trp Glu Ala Phe Gln Asp Gly Glu Lys Leu Gly Thr Gly 
305                 310                 315                 320 


Glu Asn Leu Ala Pro Trp His Pro Ile Lys Pro Gly Gly Val Leu Ile 
                325                 330                 335     


Leu Gly Gln Glu Gln Asp Thr Val Gly Gly Arg Phe Asp Ala Thr Gln 
            340                 345                 350         


Ala Phe Val Gly Glu Leu Ser Gln Phe Asn Ile Trp Asp Arg Val Leu 
        355                 360                 365             


Arg Ala Gln Glu Ile Val Asn Ile Ala Asn Cys Ser Thr Asn Met Pro 
    370                 375                 380                 


Gly Asn Ile Ile Pro Trp Val Asp Asn Asn Val Asp Val Phe Gly Gly 
385                 390                 395                 400 


Ala Ser Lys Trp Pro Val Glu Thr Cys Glu Glu Arg Leu Leu Asp Leu 
                405                 410                 415     


<210>  2247
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  2247

Val Lys Ser Phe Thr Thr Thr Leu Pro Trp Ala Thr Cys Gly His Thr 
1               5                   10                  15      


Trp Asn Thr Pro Asp Cys Val Glu Ile Phe Arg His Glu Asp Cys Ala 
            20                  25                  30          


Asn Ala Ser Leu Ala Asn Leu Thr Cys Asp Gln Leu Ala Asp Arg Arg 
        35                  40                  45              


Ser Pro Val Ile Glu Phe Trp Glu Asn Lys Val Leu Arg Leu Ser Gly 
    50                  55                  60                  


Gly Leu Glu Val Pro Gly Ala 
65                  70      


<210>  2248
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  2248

Ser Gly Asn Phe Asn Phe Gly Ala Tyr His Thr Leu Glu Glu Ile Ser 
1               5                   10                  15      


Gln Glu Met Asp Asn Leu Val Ala Glu His Pro Gly Leu Val Ser Lys 
            20                  25                  30          


Val Asn Ile Gly Ser Ser Phe Glu Asn Arg Pro Met Asn Val Leu Lys 
        35                  40                  45              


Phe Ser Thr Gly Gly Asp Lys Pro Ala Ile Trp Leu Asp Ala Gly Ile 
    50                  55                  60                  


His Ala Arg Glu Trp Val Thr Gln Ala Thr Ala Leu Trp Thr Ala Asn 
65                  70                  75                  80  


Lys Ile Val Ser Asp Tyr Gly Lys Asp Pro Ser Ile Thr Ser Ile Leu 
                85                  90                  95      


Asp Ala Leu Asp Ile Phe Leu Leu Pro Val Thr Asn Pro Asp Gly Tyr 
            100                 105                 110         


Val Phe Ser Gln Thr Lys Asn Arg Met Trp Arg Lys Thr Arg Ser Lys 
        115                 120                 125             


Val Ser Gly Ser Leu Cys Val Gly Val Asp Pro Asn Arg Asn Trp Asp 
    130                 135                 140                 


Ala Gly Phe Gly Gly Pro Gly Ala Ser Ser Asn Pro Cys Ser Asp Ser 
145                 150                 155                 160 


Tyr His Gly Pro Ser Ala Asn Ser Glu Val Glu Val Lys Ser Ile Val 
                165                 170                 175     


Asp Phe Ile Lys Ser His Gly Lys Val Lys Ala Phe Ile Thr Leu His 
            180                 185                 190         


Ser Tyr Ser Gln Leu Leu Met Phe Pro Tyr Gly Tyr Lys Cys Thr Lys 
        195                 200                 205             


Leu Asp Asp Phe Asp Glu Leu Ser Glu Val Ala Gln Lys Ala Ala Gln 
    210                 215                 220                 


Ser Leu Arg Ser Leu His Gly Thr Lys Tyr Lys Val Gly Pro Ile Cys 
225                 230                 235                 240 


Ser Val Ile Tyr Gln Ala Ser Gly Gly Ser Ile Asp Trp Ser Tyr Asp 
                245                 250                 255     


Tyr Gly Ile Lys Tyr Ser Phe Ala Phe Glu Leu Arg Asp Thr Gly Arg 
            260                 265                 270         


Tyr Gly Phe Leu Leu Pro Ala Arg Gln Ile Leu Pro Thr Ala Glu Glu 
        275                 280                 285             


Thr Trp Leu Gly Leu Lys Ala Ile Met Glu His Val Arg Asp His Pro 
    290                 295                 300                 


Tyr 
305 


<210>  2249
<211>  211
<212>  PRT
<213>  Homo Sapiens

<400>  2249

Ala Asn Ile Leu Pro Asp Ile Glu Asn Glu Asp Phe Ile Lys Asp Cys 
1               5                   10                  15      


Val Arg Ile His Asn Lys Phe Arg Ser Glu Val Lys Pro Thr Ala Ser 
            20                  25                  30          


Asp Met Leu Tyr Met Thr Trp Asp Pro Ala Leu Ala Gln Ile Ala Lys 
        35                  40                  45              


Ala Trp Ala Ser Asn Cys Gln Phe Ser His Asn Thr Arg Leu Lys Pro 
    50                  55                  60                  


Pro His Lys Leu His Pro Asn Phe Thr Ser Leu Gly Glu Asn Ile Trp 
65                  70                  75                  80  


Thr Gly Ser Val Pro Ile Phe Ser Val Ser Ser Ala Ile Thr Asn Trp 
                85                  90                  95      


Tyr Asp Glu Ile Gln Asp Tyr Asp Phe Lys Thr Arg Ile Cys Lys Lys 
            100                 105                 110         


Val Cys Gly His Tyr Thr Gln Val Val Trp Ala Asp Ser Tyr Lys Val 
        115                 120                 125             


Gly Cys Ala Val Gln Phe Cys Pro Lys Val Ser Gly Phe Asp Ala Leu 
    130                 135                 140                 


Ser Asn Gly Ala His Phe Ile Cys Asn Tyr Gly Pro Gly Gly Asn Tyr 
145                 150                 155                 160 


Pro Thr Trp Pro Tyr Lys Arg Gly Ala Thr Cys Ser Ala Cys Pro Asn 
                165                 170                 175     


Asn Asp Lys Cys Leu Asp Asn Leu Cys Val Asn Arg Gln Arg Asp Gln 
            180                 185                 190         


Val Lys Arg Tyr Tyr Ser Val Val Tyr Pro Gly Trp Pro Ile Tyr Pro 
        195                 200                 205             


Arg Asn Arg 
    210     


<210>  2250
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  2250

Ala Trp Ala Leu Phe Tyr Leu Phe Ser Ser Phe Thr Ser Glu Leu Pro 
1               5                   10                  15      


Trp Thr Thr Cys Asn Asn Phe Trp Asn Thr Glu His Cys Thr Asp Phe 
            20                  25                  30          


Leu Asn His Ser Gly Ala Gly Thr Val Thr Pro Phe Glu Asn Phe Thr 
        35                  40                  45              


Ser Pro Val Met Glu Phe Trp Glu Arg Arg Val Leu Gly Ile Thr Ser 
    50                  55                  60                  


Gly Ile His Asp Leu Gly Ser Leu Arg 
65                  70              


<210>  2251
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  2251

Ala Trp Ala Ile Phe Tyr Leu Ser Asn Cys Phe Thr Thr Glu Leu Pro 
1               5                   10                  15      


Trp Ala Thr Cys Gly His Glu Trp Asn Thr Glu Asn Cys Val Glu Phe 
            20                  25                  30          


Gln Lys Leu Asn Val Ser Asn Tyr Ser His Val Ser Leu Gln Asn Ala 
        35                  40                  45              


Thr Ser Pro Val Met Glu Phe Trp Glu His Arg Val Leu Ala Ile Ser 
    50                  55                  60                  


Asp Gly Ile Glu His Ile Gly Asn Leu Arg 
65                  70                  


<210>  2252
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2252

Ser Ser Met Thr His Val Leu Pro Trp Ala Tyr Cys Asn Asn Pro Trp 
1               5                   10                  15      


Asn Thr His Asp Cys Ala Gly Val Leu Asp Ala Ser Asn Leu Thr Asn 
            20                  25                  30          


Gly Ser Arg Pro Ala Ala Leu Pro Ser Asn Leu Ser His Leu Leu Asn 
        35                  40                  45              


His Ser Leu Gln Arg Thr Ser Pro Ser Glu Glu Tyr Trp Arg Leu Tyr 
    50                  55                  60                  


Val Leu Lys Leu Ser Asp Asp Ile Gly Asn Phe Gly Glu 
65                  70                  75          


<210>  2253
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  2253

Lys Glu Lys Ser Ser Lys Lys Gly Lys Gly Lys Lys Lys Gln Tyr Leu 
1               5                   10                  15      


Cys Pro Ser Gln Gln Ser Ala Glu Asp Leu Ala Arg Val Pro Ala Asn 
            20                  25                  30          


Ser Thr Ser Asn Ile Leu Asn Arg Leu Leu Val Ser Tyr Asp Pro Arg 
        35                  40                  45              


Ile Arg Pro Asn Phe Lys Gly Ile Pro Val Asp Val Val Val Asn Ile 
    50                  55                  60                  


Phe Ile Asn Ser Phe Gly Ser Ile Gln Glu Thr Thr Met Asp Tyr Arg 
65                  70                  75                  80  


Val Asn Ile Phe Leu Arg Gln Lys Trp Asn Asp Pro Arg Leu Lys Leu 
                85                  90                  95      


Pro Ser Asp Phe Arg Gly Ser Asp Ala Leu Thr Val Asp Pro Thr Met 
            100                 105                 110         


Tyr Lys Cys Leu Trp Lys Pro Asp Leu Phe Phe Ala Asn Glu Lys Ser 
        115                 120                 125             


Ala Asn Phe His Asp Val Thr Gln Glu Asn Ile Leu Leu Phe Ile Phe 
    130                 135                 140                 


Arg Asp Gly Asp Val Leu Val Ser Met Arg Leu Ser Ile Thr Leu Ser 
145                 150                 155                 160 


Cys Pro Leu Asp Leu Thr Leu Phe Pro Met Asp Thr Gln Arg Cys Lys 
                165                 170                 175     


Met Gln Leu Glu Ser Phe Gly Tyr Thr Thr Asp Asp Leu Arg Phe Ile 
            180                 185                 190         


Trp Gln Ser Gly Asp Pro Val Gln Leu Glu Lys Ile Ala Leu Pro Gln 
        195                 200                 205             


Phe Asp Ile Lys Lys Glu Asp Ile Glu Tyr Gly Asn Cys Thr Lys Tyr 
    210                 215                 220                 


Tyr Lys Gly Thr Gly Tyr Tyr Thr Cys Val Glu Val Ile Phe Thr Leu 
225                 230                 235                 240 


Arg Arg Gln Val Gly Phe 
                245     


<210>  2254
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2254

Gln Asn Gln Lys Glu Glu Lys Leu Cys Thr Glu Asn Phe Thr Arg Ile 
1               5                   10                  15      


Leu Asp Ser Leu Leu Asp Gly Tyr Asp Asn Arg Leu Arg Pro Gly Phe 
            20                  25                  30          


Gly Gly Pro Val Thr Glu Val Lys Thr Asp Ile Tyr Val Thr Ser Phe 
        35                  40                  45              


Gly Pro Val Ser Asp Val Glu Met Glu Tyr Thr Met Asp Val Phe Phe 
    50                  55                  60                  


Arg Gln Thr Trp Ile Asp Lys Arg Leu Lys Tyr Asp Gly Pro Ile Glu 
65                  70                  75                  80  


Ile Leu Arg Leu Asn Asn Met Met Val Thr Lys Val Trp Thr Pro Asp 
                85                  90                  95      


Thr Phe Phe Arg Asn Gly Lys Lys Ser Val Ser His Asn Met Thr Ala 
            100                 105                 110         


Pro Asn Lys Leu Phe Arg Ile Met Arg Asn Gly Thr Ile Leu Tyr Thr 
        115                 120                 125             


Met Arg Leu Thr Ile Ser Ala Glu Cys Pro Met Arg Leu Val Asp Phe 
    130                 135                 140                 


Pro Met Asp Gly His Ala Cys Pro Leu Lys Phe Gly Ser Tyr Ala Tyr 
145                 150                 155                 160 


Pro Lys Ser Glu Met Ile Tyr Thr Trp Thr Lys Gly Pro Glu Lys Ser 
                165                 170                 175     


Val Glu Val Pro Lys Glu Ser Ser Ser Leu Val Gln Tyr Asp Leu Ile 
            180                 185                 190         


Gly Gln Thr Val Ser Ser Glu Thr Ile Lys Ser Ile Thr Gly Glu Tyr 
        195                 200                 205             


Ile Val Met Thr Val Tyr Phe His Leu Arg Arg Lys Met Gly Tyr 
    210                 215                 220             


<210>  2255
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  2255

Asp Ala Ala Gln Glu Pro Thr Gly Asn Asn Ala Glu Ile Cys Leu Leu 
1               5                   10                  15      


Pro Leu Asp Tyr Gly Pro Cys Arg Ala Leu Leu Leu Arg Tyr Tyr Tyr 
            20                  25                  30          


Asp Arg Tyr Thr Gln Ser Cys Arg Gln Phe Leu Tyr Gly Gly Cys Glu 
        35                  40                  45              


Gly Asn Ala Asn Asn Phe Tyr Thr Trp Glu Ala Cys Asp Asp Ala Cys 
    50                  55                  60                  


Trp Arg Ile Glu Lys Val Pro Lys Val Cys Arg Leu Gln Val Ser Val 
65                  70                  75                  80  


Asp Asp Gln Cys Glu Gly Ser Thr Glu Lys Tyr Phe Phe Asn Leu Ser 
                85                  90                  95      


Ser Met Thr Cys Glu Lys Phe Phe Ser Gly Gly Cys His Arg Asn Arg 
            100                 105                 110         


Ile Glu Asn Arg Phe Pro Asp Glu Ala Thr Cys Met Gly Phe Cys Ala 
        115                 120                 125             


Pro Lys Lys Ile Pro Ser Phe Cys Tyr Ser Pro Lys Asp Glu Gly Leu 
    130                 135                 140                 


Cys Ser Ala Asn Val Thr Arg Tyr Tyr Phe Asn Pro Arg Tyr Arg Thr 
145                 150                 155                 160 


Cys Asp Ala Phe Thr Tyr Thr Gly Cys Gly Gly Asn Asp Asn Asn Phe 
                165                 170                 175     


Val Ser Arg Glu Asp Cys Lys Arg Ala Cys Ala Lys Ala Leu Lys Lys 
            180                 185                 190         


Lys Lys Lys Met Pro Lys Leu Arg Phe Ala Ser Arg Ile Arg Lys Ile 
        195                 200                 205             


Arg Lys Lys Gln Phe 
    210             


<210>  2256
<211>  449
<212>  PRT
<213>  Homo Sapiens

<400>  2256

Gln Gln Tyr Leu Pro Leu Pro Thr Pro Lys Val Ile Gly Ile Asp Leu 
1               5                   10                  15      


Gly Thr Thr Tyr Cys Ser Val Gly Val Phe Phe Pro Gly Thr Gly Lys 
            20                  25                  30          


Val Lys Val Ile Pro Asp Glu Asn Gly His Ile Ser Ile Pro Ser Met 
        35                  40                  45              


Val Ser Phe Thr Asp Asn Asp Val Tyr Val Gly Tyr Glu Ser Val Glu 
    50                  55                  60                  


Leu Ala Asp Ser Asn Pro Gln Asn Thr Ile Tyr Asp Ala Lys Arg Phe 
65                  70                  75                  80  


Ile Gly Lys Ile Phe Thr Ala Glu Glu Leu Glu Ala Glu Ile Gly Arg 
                85                  90                  95      


Tyr Pro Phe Lys Val Leu Asn Lys Asn Gly Met Val Glu Phe Ser Val 
            100                 105                 110         


Thr Ser Asn Glu Thr Ile Thr Val Ser Pro Glu Tyr Val Gly Ser Arg 
        115                 120                 125             


Leu Leu Leu Lys Leu Lys Glu Met Ala Glu Ala Tyr Leu Gly Met Pro 
    130                 135                 140                 


Val Ala Asn Ala Val Ile Ser Val Pro Ala Glu Phe Asp Leu Lys Gln 
145                 150                 155                 160 


Arg Asn Ser Thr Ile Glu Ala Ala Asn Leu Ala Gly Leu Lys Ile Leu 
                165                 170                 175     


Arg Val Ile Asn Glu Pro Thr Ala Ala Ala Met Ala Tyr Gly Leu His 
            180                 185                 190         


Lys Ala Asp Val Phe His Val Leu Val Ile Asp Leu Gly Gly Gly Thr 
        195                 200                 205             


Leu Asp Val Ser Leu Leu Asn Lys Gln Gly Gly Met Phe Leu Thr Arg 
    210                 215                 220                 


Ala Met Ser Gly Asn Asn Lys Leu Gly Gly Gln Asp Phe Asn Gln Arg 
225                 230                 235                 240 


Leu Leu Gln Tyr Leu Tyr Lys Gln Ile Tyr Gln Thr Tyr Gly Phe Val 
                245                 250                 255     


Pro Ser Arg Lys Glu Glu Ile His Arg Leu Arg Gln Ala Val Glu Met 
            260                 265                 270         


Val Lys Leu Asn Leu Thr Leu His Gln Ser Ala Gln Leu Ser Val Leu 
        275                 280                 285             


Leu Thr Val Glu Glu Gln Asp Arg Lys Glu Pro His Ser Ser Asp Thr 
    290                 295                 300                 


Glu Leu Pro Lys Asp Lys Leu Ser Ser Ala Asp Asp His Arg Val Asn 
305                 310                 315                 320 


Ser Gly Phe Gly Arg Gly Leu Ser Asp Lys Lys Ser Gly Glu Ser Gln 
                325                 330                 335     


Val Leu Phe Glu Thr Glu Ile Ser Arg Lys Leu Phe Asp Thr Leu Asn 
            340                 345                 350         


Glu Asp Leu Phe Gln Lys Ile Leu Val Pro Ile Gln Gln Val Leu Lys 
        355                 360                 365             


Glu Gly His Leu Glu Lys Thr Glu Ile Asp Glu Val Val Leu Val Gly 
    370                 375                 380                 


Gly Ser Thr Arg Ile Pro Arg Ile Arg Gln Val Ile Gln Glu Phe Phe 
385                 390                 395                 400 


Gly Lys Asp Pro Asn Thr Ser Val Asp Pro Asp Leu Ala Val Val Thr 
                405                 410                 415     


Gly Val Ala Ile Gln Ala Gly Ile Asp Gly Gly Phe Trp Pro Leu Gln 
            420                 425                 430         


Val Ser Ala Leu Glu Ile Pro Asn Lys His Leu Gln Lys Thr Asn Phe 
        435                 440                 445             


Asn 
    


<210>  2257
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  2257

Thr Gln Arg Cys Pro Pro Gln Cys Pro Gly Arg Cys Pro Ala Thr Pro 
1               5                   10                  15      


Pro Thr Cys Ala Pro Gly Val Arg Ala Val Leu Asp Gly Cys Ser Cys 
            20                  25                  30          


Cys Leu Val Cys Ala Arg Gln Arg Gly Glu Ser Cys Ser Asp Leu Glu 
        35                  40                  45              


Pro Cys Asp Glu Ser Ser Gly Leu Tyr Cys Asp Arg Ser Ala Asp Pro 
    50                  55                  60                  


Ser Lys Gln Thr Gly Ile Cys Thr Ala Val Glu Gly Asp Asn Cys Val 
65                  70                  75                  80  


Phe Asp Gly Val Ile Tyr Arg Ser Gly Glu Lys Phe Gln Pro Ser Cys 
                85                  90                  95      


Lys Phe Gln Cys Thr Cys Arg Asp Gly Gln Ile Gly Cys Val Pro Arg 
            100                 105                 110         


Cys Gln Leu Asp Val Leu Leu Pro Glu Pro Asn Cys Pro Ala Pro Arg 
        115                 120                 125             


Lys Val Glu Val Pro Gly Glu Cys Cys Glu Lys Trp Ile Cys Gly Pro 
    130                 135                 140                 


Asp Glu Glu Asp Ser Leu Gly Gly Leu Thr Leu Ala Ala Tyr Arg Pro 
145                 150                 155                 160 


Glu Ala Thr Leu Gly Val Glu Val Ser Asp Ser Ser Val Asn Cys Ile 
                165                 170                 175     


Glu Gln Thr Thr Glu Trp Thr Ala Cys Ser Lys Ser Cys Gly Met Gly 
            180                 185                 190         


Phe Ser Thr Arg Val Thr Asn Arg Asn Arg Gln Cys Glu Met Leu Lys 
        195                 200                 205             


Gln Thr Arg Leu Cys Met Val Arg Pro Cys Glu Gln Glu Pro Glu Gln 
    210                 215                 220                 


Pro Thr Asp Lys Lys Gly Lys Lys Cys Leu Arg Thr Lys Lys Ser Leu 
225                 230                 235                 240 


Lys Ala Ile His Leu Gln Phe Lys Asn Cys Thr Ser Leu His Thr Tyr 
                245                 250                 255     


Lys Pro Arg Phe Cys Gly Val Cys Ser Asp Gly Arg Cys Cys Thr Pro 
            260                 265                 270         


His Asn Thr Lys Thr Ile Gln Ala Glu Phe Gln Cys Ser Pro Gly Gln 
        275                 280                 285             


Ile Val Lys Lys Pro Val Met Val Ile Gly Thr Cys Thr Cys His Thr 
    290                 295                 300                 


Asn Cys Pro Lys Asn Asn Glu Ala Phe Leu Gln Glu Leu Glu Leu Lys 
305                 310                 315                 320 


Thr Thr Arg Gly Lys Met 
                325     


<210>  2258
<211>  64
<212>  PRT
<213>  Homo Sapiens

<400>  2258

Ala His Asn Lys Phe His Asp Phe Ala Asp Arg Lys Asp Trp Asp Ala 
1               5                   10                  15      


Phe His Pro Thr Leu Val Ala Glu Gly Leu Phe Ala Phe Ala Asn Val 
            20                  25                  30          


Leu Ser Tyr Leu Arg Leu Phe Phe Met Tyr Thr Thr Ser Ser Ile Leu 
        35                  40                  45              


Gly Pro Leu Gln Ile Ser Met Gly Gln Met Leu Gln Asp Phe Gly Lys 
    50                  55                  60                  


<210>  2259
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  2259

Phe Arg Ile Cys Ala Phe Asn Ala Gln Arg Leu Thr Leu Ala Lys Val 
1               5                   10                  15      


Ala Arg Glu Gln Val Met Asp Thr Leu Val Arg Ile Leu Ala Arg Cys 
            20                  25                  30          


Asp Ile Met Val Leu Gln Glu Val Val Asp Ser Ser Gly Ser Ala Ile 
        35                  40                  45              


Pro Leu Leu Leu Arg Glu Leu Asn Arg Phe Asp Gly Ser Gly Pro Tyr 
    50                  55                  60                  


Ser Thr Leu Ser Ser Pro Gln Leu Gly Arg Ser Thr Tyr Met Glu Thr 
65                  70                  75                  80  


Tyr Val Tyr Phe Tyr Arg Ser His Lys Thr Gln Val Leu Ser Ser Tyr 
                85                  90                  95      


Val Tyr Asn Asp Glu Asp Asp Val Phe Ala Arg Glu Pro Phe Val Ala 
            100                 105                 110         


Gln Phe Ser Leu Pro Ser Asn Val Leu Pro Ser Leu Val Leu Val Pro 
        115                 120                 125             


Leu His Thr Thr Pro Lys Ala Val Glu Lys Glu Leu Asn Ala Leu Tyr 
    130                 135                 140                 


Asp Val Phe Leu Glu Val Ser Gln His Trp Gln Ser Lys Asp Val Ile 
145                 150                 155                 160 


Leu Leu Gly Asp Phe Asn Ala Asp Cys Ala Ser Leu Thr Lys Lys Arg 
                165                 170                 175     


Leu Asp Lys Leu Glu Leu Arg Thr Glu Pro Gly Phe His Trp Val Ile 
            180                 185                 190         


Ala Asp Gly Glu Asp Thr Thr Val Arg Ala Ser Thr His Cys Thr Tyr 
        195                 200                 205             


Asp Arg Val Val Leu His Gly Glu Arg Cys Arg Ser Leu Leu His Thr 
    210                 215                 220                 


Ala Ala Ala Phe Asp Phe Pro Thr Ser Phe Gln Leu Thr Glu Glu Glu 
225                 230                 235                 240 


Ala Leu Asn Ile Ser Asp His Tyr Pro Val Glu Val Glu Leu Lys Leu 
                245                 250                 255     


Ser Gln Ala His Ser Val Gln Pro Leu Ser Leu Thr Val Leu Leu Leu 
            260                 265                 270         


Leu Ser Leu Leu Ser Pro Gln Leu Cys Pro Ala Ala 
        275                 280                 


<210>  2260
<211>  377
<212>  PRT
<213>  Homo Sapiens

<400>  2260

Met Ala Glu Gly Asn His Arg Lys Lys Pro Leu Lys Val Leu Glu Ser 
1               5                   10                  15      


Leu Gly Lys Asp Phe Leu Thr Gly Val Leu Asp Asn Leu Val Glu Gln 
            20                  25                  30          


Asn Val Leu Asn Trp Lys Glu Glu Glu Lys Lys Lys Tyr Tyr Asp Ala 
        35                  40                  45              


Lys Thr Glu Asp Lys Val Arg Val Met Ala Asp Ser Met Gln Glu Lys 
    50                  55                  60                  


Gln Arg Met Ala Gly Gln Met Leu Leu Gln Thr Phe Phe Asn Ile Asp 
65                  70                  75                  80  


Gln Ile Ser Pro Asn Lys Lys Ala His Pro Asn Met Glu Ala Gly Pro 
                85                  90                  95      


Pro Glu Ser Gly Glu Ser Thr Asp Ala Leu Lys Leu Cys Pro His Glu 
            100                 105                 110         


Glu Phe Leu Arg Leu Cys Lys Glu Arg Ala Glu Glu Ile Tyr Pro Ile 
        115                 120                 125             


Lys Glu Arg Asn Asn Arg Thr Arg Leu Ala Leu Ile Ile Cys Asn Thr 
    130                 135                 140                 


Glu Phe Asp His Leu Pro Pro Arg Asn Gly Ala Asp Phe Asp Ile Thr 
145                 150                 155                 160 


Gly Met Lys Glu Leu Leu Glu Gly Leu Asp Tyr Ser Val Asp Val Glu 
                165                 170                 175     


Glu Asn Leu Thr Ala Arg Asp Met Glu Ser Ala Leu Arg Ala Phe Ala 
            180                 185                 190         


Thr Arg Pro Glu His Lys Ser Ser Asp Ser Thr Phe Leu Val Leu Met 
        195                 200                 205             


Ser His Gly Ile Leu Glu Gly Ile Cys Gly Thr Val His Asp Glu Lys 
    210                 215                 220                 


Lys Pro Asp Val Leu Leu Tyr Asp Thr Ile Phe Gln Ile Phe Asn Asn 
225                 230                 235                 240 


Arg Asn Cys Leu Ser Leu Lys Asp Lys Pro Lys Val Ile Ile Val Gln 
                245                 250                 255     


Ala Cys Arg Gly Ala Asn Arg Gly Glu Leu Trp Val Arg Asp Ser Pro 
            260                 265                 270         


Ala Ser Leu Glu Val Ala Ser Ser Gln Ser Ser Glu Asn Leu Glu Glu 
        275                 280                 285             


Asp Ala Val Tyr Lys Thr His Val Glu Lys Asp Phe Ile Ala Phe Cys 
    290                 295                 300                 


Ser Ser Thr Pro His Asn Val Ser Trp Arg Asp Ser Thr Met Gly Ser 
305                 310                 315                 320 


Ile Phe Ile Thr Gln Leu Ile Thr Cys Phe Gln Lys Tyr Ser Trp Cys 
                325                 330                 335     


Cys His Leu Glu Glu Val Phe Arg Lys Val Gln Gln Ser Phe Glu Thr 
            340                 345                 350         


Pro Arg Ala Lys Ala Gln Met Pro Thr Ile Glu Arg Leu Ser Met Thr 
        355                 360                 365             


Arg Tyr Phe Tyr Leu Phe Pro Gly Asn 
    370                 375         


<210>  2261
<211>  158
<212>  PRT
<213>  Homo Sapiens

<400>  2261

Thr Gln Asp Cys Ser Phe Gln His Ser Pro Ile Ser Ser Asp Phe Ala 
1               5                   10                  15      


Val Lys Ile Arg Glu Leu Ser Asp Tyr Leu Leu Gln Asp Tyr Pro Val 
            20                  25                  30          


Thr Val Ala Ser Asn Leu Gln Asp Glu Glu Leu Cys Gly Gly Leu Trp 
        35                  40                  45              


Arg Leu Val Leu Ala Gln Arg Trp Met Glu Arg Leu Lys Thr Val Ala 
    50                  55                  60                  


Gly Ser Lys Met Gln Gly Leu Leu Glu Arg Val Asn Thr Glu Ile His 
65                  70                  75                  80  


Phe Val Thr Lys Cys Ala Phe Gln Pro Pro Pro Ser Cys Leu Arg Phe 
                85                  90                  95      


Val Gln Thr Asn Ile Ser Arg Leu Leu Gln Glu Thr Ser Glu Gln Leu 
            100                 105                 110         


Val Ala Leu Lys Pro Trp Ile Thr Arg Gln Asn Phe Ser Arg Cys Leu 
        115                 120                 125             


Glu Leu Gln Cys Gln Pro Asp Ser Ser Thr Leu Pro Pro Pro Trp Ser 
    130                 135                 140                 


Pro Arg Pro Leu Glu Ala Thr Ala Pro Thr Ala Pro Gln Pro 
145                 150                 155             


<210>  2262
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2262

Ile Ile Asp Gly Ala Pro Cys Ala Arg Gly Ser His Pro Trp Gln Val 
1               5                   10                  15      


Ala Leu Leu Ser Gly Asn Gln Leu His Cys Gly Gly Val Leu Val Asn 
            20                  25                  30          


Glu Arg Trp Val Leu Thr Ala Ala His Cys Lys Met Asn Glu Tyr Thr 
        35                  40                  45              


Val His Leu Gly Ser Asp Thr Leu Gly Asp Arg Arg Ala Gln Arg Ile 
    50                  55                  60                  


Lys Ala Ser Lys Ser Phe Arg His Pro Gly Tyr Ser Thr Gln Thr His 
65                  70                  75                  80  


Val Asn Asp Leu Met Leu Val Lys Leu Asn Ser Gln Ala Arg Leu Ser 
                85                  90                  95      


Ser Met Val Lys Lys Val Arg Leu Pro Ser Arg Cys Glu Pro Pro Gly 
            100                 105                 110         


Thr Thr Cys Thr Val Ser Gly Trp Gly Thr Thr Thr Ser Pro Asp Val 
        115                 120                 125             


Thr Phe Pro Ser Asp Leu Met Cys Val Asp Val Lys Leu Ile Ser Pro 
    130                 135                 140                 


Gln Asp Cys Thr Lys Val Tyr Lys Asp Leu Leu Glu Asn Ser Met Leu 
145                 150                 155                 160 


Cys Ala Gly Ile Pro Asp Ser Lys Lys Asn Ala Cys Asn Gly Asp Ser 
                165                 170                 175     


Gly Gly Pro Leu Val Cys Arg Gly Thr Leu Gln Gly Leu Val Ser Trp 
            180                 185                 190         


Gly Thr Phe Pro Cys Gly Gln Pro Asn Asp Pro Gly Val Tyr Thr Gln 
        195                 200                 205             


Val Cys Lys Phe Thr Lys Trp Ile Asn Asp Thr Met Lys Lys His Arg 
    210                 215                 220                 


<210>  2263
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  2263

Ile Ile Gly Gly Lys Glu Val Ser Pro His Ser Arg Pro Phe Met Ala 
1               5                   10                  15      


Ser Ile Gln Tyr Gly Gly His His Val Cys Gly Gly Val Leu Ile Asp 
            20                  25                  30          


Pro Gln Trp Val Leu Thr Ala Ala His Cys Gln Tyr Arg Phe Thr Lys 
        35                  40                  45              


Gly Gln Ser Pro Thr Val Val Leu Gly Ala His Ser Leu Ser Lys Asn 
    50                  55                  60                  


Glu Ala Ser Lys Gln Thr Leu Glu Ile Lys Lys Phe Ile Pro Phe Ser 
65                  70                  75                  80  


Arg Val Thr Ser Asp Pro Gln Ser Asn Asp Ile Met Leu Val Lys Leu 
                85                  90                  95      


Gln Thr Ala Ala Lys Leu Asn Lys His Val Lys Met Leu His Ile Arg 
            100                 105                 110         


Ser Lys Thr Ser Leu Arg Ser Gly Thr Lys Cys Lys Val Thr Gly Trp 
        115                 120                 125             


Gly Ala Thr Asp Pro Asp Ser Leu Arg Pro Ser Asp Thr Leu Arg Glu 
    130                 135                 140                 


Val Thr Val Thr Val Leu Ser Arg Lys Leu Cys Asn Ser Gln Ser Tyr 
145                 150                 155                 160 


Tyr Asn Gly Asp Pro Phe Ile Thr Lys Asp Met Val Cys Ala Gly Asp 
                165                 170                 175     


Ala Lys Gly Gln Lys Asp Ser Cys Lys Gly Asp Ser Gly Gly Pro Leu 
            180                 185                 190         


Ile Cys Lys Gly Val Phe His Ala Ile Val Ser Gly Gly His Glu Cys 
        195                 200                 205             


Gly Val Ala Thr Lys Pro Gly Ile Tyr Thr Leu Leu Thr Lys Lys Tyr 
    210                 215                 220                 


Gln Thr Trp Ile Lys Ser Asn Leu Val Pro Pro His Thr Asn 
225                 230                 235             


<210>  2264
<211>  430
<212>  PRT
<213>  Homo Sapiens

<400>  2264

Tyr Ala Ile Gln Gly Leu Lys Trp Gln His Asn Glu Ile Thr Phe Cys 
1               5                   10                  15      


Ile Gln Asn Tyr Thr Pro Lys Val Gly Glu Tyr Ala Thr Tyr Glu Ala 
            20                  25                  30          


Ile Arg Lys Ala Phe Arg Val Trp Glu Ser Ala Thr Pro Leu Arg Phe 
        35                  40                  45              


Arg Glu Val Pro Tyr Ala Tyr Ile Arg Glu Gly His Glu Lys Gln Ala 
    50                  55                  60                  


Asp Ile Met Ile Phe Phe Ala Glu Gly Phe His Gly Asp Ser Thr Pro 
65                  70                  75                  80  


Phe Asp Gly Glu Gly Gly Phe Leu Ala His Ala Tyr Phe Pro Gly Pro 
                85                  90                  95      


Asn Ile Gly Gly Asp Thr His Phe Asp Ser Ala Glu Pro Trp Thr Val 
            100                 105                 110         


Arg Asn Glu Asp Leu Asn Gly Asn Asp Ile Phe Leu Val Ala Val His 
        115                 120                 125             


Glu Leu Gly His Ala Leu Gly Leu Glu His Ser Ser Asp Pro Ser Ala 
    130                 135                 140                 


Ile Met Ala Pro Phe Tyr Gln Trp Met Asp Thr Glu Asn Phe Val Leu 
145                 150                 155                 160 


Pro Asp Asp Asp Arg Arg Gly Ile Gln Gln Leu Tyr Gly Gly Glu Ser 
                165                 170                 175     


Gly Phe Pro Thr Lys Met Pro Pro Gln Pro Arg Thr Thr Ser Arg Pro 
            180                 185                 190         


Ser Val Pro Asp Lys Pro Lys Asn Pro Thr Tyr Gly Pro Asn Ile Cys 
        195                 200                 205             


Asp Gly Asn Phe Asp Thr Val Ala Met Leu Arg Gly Glu Met Phe Val 
    210                 215                 220                 


Phe Lys Glu Arg Trp Phe Trp Arg Val Arg Asn Asn Gln Val Met Asp 
225                 230                 235                 240 


Gly Tyr Pro Met Pro Ile Gly Gln Phe Trp Arg Gly Leu Pro Ala Ser 
                245                 250                 255     


Ile Asn Thr Ala Tyr Glu Arg Lys Asp Gly Lys Phe Val Phe Phe Lys 
            260                 265                 270         


Gly Asp Lys His Trp Val Phe Asp Glu Ala Ser Leu Glu Pro Gly Tyr 
        275                 280                 285             


Pro Lys His Ile Lys Glu Leu Gly Arg Gly Leu Pro Thr Asp Lys Ile 
    290                 295                 300                 


Asp Ala Ala Leu Phe Trp Met Pro Asn Gly Lys Thr Tyr Phe Phe Arg 
305                 310                 315                 320 


Gly Asn Lys Tyr Tyr Arg Phe Asn Glu Glu Leu Arg Ala Val Asp Ser 
                325                 330                 335     


Glu Tyr Pro Lys Asn Ile Lys Val Trp Glu Gly Ile Pro Glu Ser Pro 
            340                 345                 350         


Arg Gly Ser Phe Met Gly Ser Asp Glu Val Phe Thr Tyr Phe Tyr Lys 
        355                 360                 365             


Gly Asn Lys Tyr Trp Lys Phe Asn Asn Gln Lys Leu Lys Val Glu Pro 
    370                 375                 380                 


Gly Tyr Pro Lys Ser Ala Leu Arg Asp Trp Met Gly Cys Pro Ser Gly 
385                 390                 395                 400 


Gly Arg Pro Asp Glu Gly Thr Glu Glu Glu Thr Glu Val Ile Ile Ile 
                405                 410                 415     


Glu Val Asp Glu Glu Gly Gly Gly Ala Val Ser Ala Ala Ala 
            420                 425                 430 


<210>  2265
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  2265

Met Ser Ser Glu Ser Lys Glu Gln His Asn Val Ser Pro Arg Asp Ser 
1               5                   10                  15      


Ala Glu Gly Asn Asp Ser Tyr Pro Ser Gly Ile His Leu Glu Leu Gln 
            20                  25                  30          


Arg Glu Ser Ser Thr Asp Phe Lys Gln Phe Glu Thr Asn Asp Gln Cys 
        35                  40                  45              


Arg Pro Tyr His Arg Ile Leu Ile Glu Arg Gln Glu Lys Ser Asp Thr 
    50                  55                  60                  


Asn Phe Lys Glu Phe Val Ile Lys Lys Leu Gln Lys Asn Cys Gln Cys 
65                  70                  75                  80  


Ser Pro Ala Lys Ala Lys Asn Met Ile Leu Gly Phe Leu Pro Val Leu 
                85                  90                  95      


Gln Trp Leu Pro Lys Tyr Asp Leu Lys Lys Asn Ile Leu Gly Asp 
            100                 105                 110     


<210>  2266
<211>  400
<212>  PRT
<213>  Homo Sapiens

<400>  2266

Ala Glu Val Lys Lys Pro Ala Ala Ala Ala Ala Pro Gly Thr Ala Glu 
1               5                   10                  15      


Lys Leu Ser Pro Lys Ala Ala Thr Leu Ala Glu Arg Ser Ala Gly Leu 
            20                  25                  30          


Ala Phe Ser Leu Tyr Gln Ala Met Ala Lys Asp Gln Ala Val Glu Asn 
        35                  40                  45              


Ile Leu Val Ser Pro Val Val Val Ala Ser Ser Leu Gly Leu Val Ser 
    50                  55                  60                  


Leu Gly Gly Lys Ala Thr Thr Ala Ser Gln Ala Lys Ala Val Leu Ser 
65                  70                  75                  80  


Ala Glu Gln Leu Arg Asp Glu Glu Val His Ala Gly Leu Gly Glu Leu 
                85                  90                  95      


Leu Arg Ser Leu Ser Asn Ser Thr Ala Arg Asn Val Thr Trp Lys Leu 
            100                 105                 110         


Gly Ser Arg Leu Tyr Gly Pro Ser Ser Val Ser Phe Ala Asp Asp Phe 
        115                 120                 125             


Val Arg Ser Ser Lys Gln His Tyr Asn Cys Glu His Ser Lys Ile Asn 
    130                 135                 140                 


Phe Arg Asp Lys Arg Ser Ala Leu Gln Ser Ile Asn Glu Trp Ala Ala 
145                 150                 155                 160 


Gln Thr Thr Asp Gly Lys Leu Pro Glu Val Thr Lys Asp Val Glu Arg 
                165                 170                 175     


Thr Asp Gly Ala Leu Leu Val Asn Ala Met Phe Phe Lys Pro His Trp 
            180                 185                 190         


Asp Glu Lys Phe His His Lys Met Val Asp Asn Arg Gly Phe Met Val 
        195                 200                 205             


Thr Arg Ser Tyr Thr Val Gly Val Met Met Met His Arg Thr Gly Leu 
    210                 215                 220                 


Tyr Asn Tyr Tyr Asp Asp Glu Lys Glu Lys Leu Gln Ile Val Glu Met 
225                 230                 235                 240 


Pro Leu Ala His Lys Leu Ser Ser Leu Ile Ile Leu Met Pro His His 
                245                 250                 255     


Val Glu Pro Leu Glu Arg Leu Glu Lys Leu Leu Thr Lys Glu Gln Leu 
            260                 265                 270         


Lys Ile Trp Met Gly Lys Met Gln Lys Lys Ala Val Ala Ile Ser Leu 
        275                 280                 285             


Pro Lys Gly Val Val Glu Val Thr His Asp Leu Gln Lys His Leu Ala 
    290                 295                 300                 


Gly Leu Gly Leu Thr Glu Ala Ile Asp Lys Asn Lys Ala Asp Leu Ser 
305                 310                 315                 320 


Arg Met Ser Gly Lys Lys Asp Leu Tyr Leu Ala Ser Val Phe His Ala 
                325                 330                 335     


Thr Ala Phe Glu Leu Asp Thr Asp Gly Asn Pro Phe Asp Gln Asp Ile 
            340                 345                 350         


Tyr Gly Arg Glu Glu Leu Arg Ser Pro Lys Leu Phe Tyr Ala Asp His 
        355                 360                 365             


Pro Phe Ile Phe Leu Val Arg Asp Thr Gln Ser Gly Ser Leu Leu Phe 
    370                 375                 380                 


Ile Gly Arg Leu Val Arg Pro Lys Gly Asp Lys Met Arg Asp Glu Leu 
385                 390                 395                 400 


<210>  2267
<211>  279
<212>  PRT
<213>  Homo Sapiens

<400>  2267

Asp Pro Pro Ala Pro Leu Pro Leu Val Ile Trp His Gly Met Gly Asp 
1               5                   10                  15      


Ser Cys Cys Asn Pro Leu Ser Met Gly Ala Ile Lys Lys Met Val Glu 
            20                  25                  30          


Lys Lys Ile Pro Gly Ile Tyr Val Leu Ser Leu Glu Ile Gly Lys Thr 
        35                  40                  45              


Leu Met Glu Asp Val Glu Asn Ser Phe Phe Leu Asn Val Asn Ser Gln 
    50                  55                  60                  


Val Thr Thr Val Cys Gln Ala Leu Ala Lys Asp Pro Lys Leu Gln Gln 
65                  70                  75                  80  


Gly Tyr Asn Ala Met Gly Phe Ser Gln Gly Gly Gln Phe Leu Arg Ala 
                85                  90                  95      


Val Ala Gln Arg Cys Pro Ser Pro Pro Met Ile Asn Leu Ile Ser Val 
            100                 105                 110         


Gly Gly Gln His Gln Gly Val Phe Gly Leu Pro Arg Cys Pro Gly Glu 
        115                 120                 125             


Ser Ser His Ile Cys Asp Phe Ile Arg Lys Thr Leu Asn Ala Gly Ala 
    130                 135                 140                 


Tyr Ser Lys Val Val Gln Glu Arg Leu Val Gln Ala Glu Tyr Trp His 
145                 150                 155                 160 


Asp Pro Ile Lys Glu Asp Val Tyr Arg Asn His Ser Ile Phe Leu Ala 
                165                 170                 175     


Asp Ile Asn Gln Glu Arg Gly Ile Asn Glu Ser Tyr Lys Lys Asn Leu 
            180                 185                 190         


Met Ala Leu Lys Lys Phe Val Met Val Lys Phe Leu Asn Asp Ser Ile 
        195                 200                 205             


Val Asp Pro Val Asp Ser Glu Trp Phe Gly Phe Tyr Arg Ser Gly Gln 
    210                 215                 220                 


Ala Lys Glu Thr Ile Pro Leu Gln Glu Thr Ser Leu Tyr Thr Gln Asp 
225                 230                 235                 240 


Arg Leu Gly Leu Lys Glu Met Asp Asn Ala Gly Gln Leu Val Phe Leu 
                245                 250                 255     


Ala Thr Glu Gly Asp His Leu Gln Leu Ser Glu Glu Trp Phe Tyr Ala 
            260                 265                 270         


His Ile Ile Pro Phe Leu Gly 
        275                 


<210>  2268
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  2268

Ile Ile Gly Gly Arg Glu Val Ile Pro His Ser Arg Pro Tyr Met Ala 
1               5                   10                  15      


Ser Leu Gln Arg Asn Gly Ser His Leu Cys Gly Gly Val Leu Val His 
            20                  25                  30          


Pro Lys Trp Val Leu Thr Ala Ala His Cys Leu Ala Gln Arg Met Ala 
        35                  40                  45              


Gln Leu Arg Leu Val Leu Gly Leu His Thr Leu Asp Ser Pro Gly Leu 
    50                  55                  60                  


Thr Phe His Ile Lys Ala Ala Ile Gln His Pro Arg Tyr Lys Pro Val 
65                  70                  75                  80  


Pro Ala Leu Glu Asn Asp Leu Ala Leu Leu Gln Leu Asp Gly Lys Val 
                85                  90                  95      


Lys Pro Ser Arg Thr Ile Arg Pro Leu Ala Leu Pro Ser Lys Arg Gln 
            100                 105                 110         


Val Val Ala Ala Gly Thr Arg Cys Ser Met Ala Gly Trp Gly Leu Thr 
        115                 120                 125             


His Gln Gly Gly Arg Leu Ser Arg Val Leu Arg Glu Leu Asp Leu Gln 
    130                 135                 140                 


Val Leu Asp Thr Arg Met Cys Asn Asn Ser Arg Phe Trp Asn Gly Ser 
145                 150                 155                 160 


Leu Ser Pro Ser Met Val Cys Leu Ala Ala Asp Ser Lys Asp Gln Ala 
                165                 170                 175     


Pro Cys Lys Gly Asp Ser Gly Gly Pro Leu Val Cys Gly Lys Gly Arg 
            180                 185                 190         


Val Leu Ala Gly Val Leu Ser Phe Ser Ser Arg Val Cys Thr Asp Ile 
        195                 200                 205             


Phe Lys Pro Pro Val Ala Thr Ala Val Ala Pro Tyr Val Ser Trp Ile 
    210                 215                 220                 


Arg Lys Val Thr Gly Arg Ser Ala 
225                 230         


<210>  2269
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2269

Cys Leu Tyr Val Leu Met Gln Thr Val Asp Pro Tyr Thr Pro Asp Tyr 
1               5                   10                  15      


Gln Asp Gln Leu Arg Ser Pro Gly Val Thr Leu Arg Pro Asp Val Tyr 
            20                  25                  30          


Gly Glu Lys Gly Leu Glu Ile Val Tyr Asn Val Ser Asp Asn Arg Thr 
        35                  40                  45              


Trp Ala Asp Leu Thr Gln Thr Leu His Ala Phe Leu Ala Gly Tyr Ser 
    50                  55                  60                  


Pro Ala Ala Gln Glu Asp Ser Ile Asn Cys Thr Ser Glu Gln Tyr Phe 
65                  70                  75                  80  


Phe Gln Glu Ser Phe Arg Ala Pro Asn His Thr Lys Phe Ser Cys Lys 
                85                  90                  95      


Phe Thr Ala Asp Met Leu Gln Asn Cys Ser Gly Leu Ala Asp Pro Asn 
            100                 105                 110         


Phe Gly Phe Glu Glu Gly Lys Pro Cys Phe Ile Ile Lys Met Asn Arg 
        115                 120                 125             


Ile Val Lys Phe Leu Pro Ser Asn Gly Ser Ala Pro Arg Val Asp Cys 
    130                 135                 140                 


Ala Phe Leu Asp Gln Pro Arg Glu Leu Gly Gln Pro Leu Gln Val Lys 
145                 150                 155                 160 


Tyr Tyr Pro Pro Asn Gly Thr Phe Ser Leu His Tyr Phe Pro Tyr Tyr 
                165                 170                 175     


Gly Lys Lys Ala Gln Pro His Tyr Ser Asn Pro Leu Val Ala Ala Lys 
            180                 185                 190         


Leu Leu Asn Ile Pro Arg Asn Ala Glu Val Ala Ile Val Cys Lys Val 
        195                 200                 205             


Met Ala Glu His Val Thr Phe Asn Asn Pro His Asp Pro Tyr Glu Gly 
    210                 215                 220                 


Lys Val Glu Phe Lys Leu Lys Ile Glu Lys 
225                 230                 


<210>  2270
<211>  461
<212>  PRT
<213>  Homo Sapiens

<400>  2270

Arg Thr Tyr Leu Ser Trp Glu Val Ser Val Ser Leu Ser Val Gly Phe 
1               5                   10                  15      


Lys Thr Met Asp Phe Pro Ala Val Thr Ile Cys Asn Ala Ser Pro Phe 
            20                  25                  30          


Lys Tyr Ser Lys Ile Lys His Leu Leu Lys Asp Leu Asp Glu Leu Met 
        35                  40                  45              


Glu Ala Val Leu Glu Arg Ile Leu Ala Pro Glu Leu Ser His Ala Asn 
    50                  55                  60                  


Ala Thr Arg Asn Leu Asn Phe Ser Ile Trp Asn His Thr Pro Leu Val 
65                  70                  75                  80  


Leu Ile Asp Glu Arg Asn Pro His His Pro Met Val Leu Asp Leu Phe 
                85                  90                  95      


Gly Asp Asn His Asn Gly Leu Thr Ser Ser Ser Ala Ser Glu Lys Ile 
            100                 105                 110         


Cys Asn Ala His Gly Cys Lys Met Ala Met Arg Leu Cys Ser Leu Asn 
        115                 120                 125             


Arg Thr Gln Cys Thr Phe Arg Asn Phe Thr Ser Ala Thr Gln Ala Leu 
    130                 135                 140                 


Thr Glu Trp Tyr Ile Leu Gln Ala Thr Asn Ile Phe Ala Gln Val Pro 
145                 150                 155                 160 


Gln Gln Glu Leu Val Glu Met Ser Tyr Pro Gly Glu Gln Met Ile Leu 
                165                 170                 175     


Ala Cys Leu Phe Gly Ala Glu Pro Cys Asn Tyr Arg Asn Phe Thr Ser 
            180                 185                 190         


Ile Phe Tyr Pro His Tyr Gly Asn Cys Tyr Ile Phe Asn Trp Gly Met 
        195                 200                 205             


Thr Glu Lys Ala Leu Pro Ser Ala Asn Pro Gly Thr Glu Phe Gly Leu 
    210                 215                 220                 


Lys Leu Ile Leu Asp Ile Gly Gln Glu Asp Tyr Val Pro Phe Leu Ala 
225                 230                 235                 240 


Ser Thr Ala Gly Val Arg Leu Met Leu His Glu Gln Arg Ser Tyr Pro 
                245                 250                 255     


Phe Ile Arg Asp Glu Gly Ile Tyr Ala Met Ser Gly Thr Glu Thr Ser 
            260                 265                 270         


Ile Gly Val Leu Val Asp Lys Leu Gln Arg Met Gly Glu Pro Tyr Ser 
        275                 280                 285             


Pro Cys Thr Val Asn Gly Ser Glu Val Pro Val Gln Asn Phe Tyr Ser 
    290                 295                 300                 


Asp Tyr Asn Thr Thr Tyr Ser Ile Gln Ala Cys Leu Arg Ser Cys Phe 
305                 310                 315                 320 


Gln Asp His Met Ile Arg Asn Cys Asn Cys Gly His Tyr Leu Tyr Pro 
                325                 330                 335     


Leu Pro Arg Gly Glu Lys Tyr Cys Asn Asn Arg Asp Phe Pro Asp Trp 
            340                 345                 350         


Ala His Cys Tyr Ser Asp Leu Gln Met Ser Val Ala Gln Arg Glu Thr 
        355                 360                 365             


Cys Ile Gly Met Cys Lys Glu Ser Cys Asn Asp Thr Gln Tyr Lys Met 
    370                 375                 380                 


Thr Ile Ser Met Ala Asp Trp Pro Ser Glu Ala Ser Glu Asp Trp Ile 
385                 390                 395                 400 


Phe His Val Leu Ser Gln Glu Arg Asp Gln Ser Thr Asn Ile Thr Leu 
                405                 410                 415     


Ser Arg Lys Gly Ile Val Lys Leu Asn Ile Tyr Phe Gln Glu Phe Asn 
            420                 425                 430         


Tyr Arg Thr Ile Glu Glu Ser Ala Ala Asn Asn Ile Val Trp Leu Leu 
        435                 440                 445             


Ser Asn Leu Gly Gly Gln Phe Gly Phe Trp Met Gly Gly 
    450                 455                 460     


<210>  2271
<211>  465
<212>  PRT
<213>  Homo Sapiens

<400>  2271

Ser Phe Tyr Thr Val Ser Val Ser Ile Lys Val His Phe Arg Lys Leu 
1               5                   10                  15      


Asp Phe Pro Ala Val Thr Ile Cys Asn Ile Asn Pro Tyr Lys Tyr Ser 
            20                  25                  30          


Thr Val Arg His Leu Leu Ala Asp Leu Glu Gln Glu Thr Arg Glu Ala 
        35                  40                  45              


Leu Lys Ser Leu Tyr Gly Phe Pro Glu Ser Arg Lys Arg Arg Glu Ala 
    50                  55                  60                  


Glu Ser Trp Asn Ser Val Ser Glu Gly Lys Gln Pro Arg Phe Ser His 
65                  70                  75                  80  


Arg Ile Pro Leu Leu Ile Phe Asp Gln Asp Glu Lys Gly Lys Ala Arg 
                85                  90                  95      


Asp Phe Phe Thr Gly Arg Lys Arg Lys Val Gly Gly Ser Ile Ile His 
            100                 105                 110         


Lys Ala Ser Asn Val Met His Ile Glu Ser Lys Gln Val Val Gly Phe 
        115                 120                 125             


Gln Leu Cys Ser Asn Asp Thr Ser Asp Cys Ala Thr Tyr Thr Phe Ser 
    130                 135                 140                 


Ser Gly Ile Asn Ala Ile Gln Glu Trp Tyr Lys Leu His Tyr Met Asn 
145                 150                 155                 160 


Ile Met Ala Gln Val Pro Leu Glu Lys Lys Ile Asn Met Ser Tyr Ser 
                165                 170                 175     


Ala Glu Glu Leu Leu Val Thr Cys Phe Phe Asp Gly Val Ser Cys Asp 
            180                 185                 190         


Ala Arg Asn Phe Thr Leu Phe His His Pro Met His Gly Asn Cys Tyr 
        195                 200                 205             


Thr Phe Asn Asn Arg Glu Asn Glu Thr Ile Leu Ser Thr Ser Met Gly 
    210                 215                 220                 


Gly Ser Glu Tyr Gly Leu Gln Val Ile Leu Tyr Ile Asn Glu Glu Glu 
225                 230                 235                 240 


Tyr Asn Pro Phe Leu Val Ser Ser Thr Gly Ala Lys Val Ile Ile His 
                245                 250                 255     


Arg Gln Asp Glu Tyr Pro Phe Val Glu Asp Val Gly Thr Glu Ile Glu 
            260                 265                 270         


Thr Ala Met Val Thr Ser Ile Gly Met His Leu Thr Glu Ser Phe Lys 
        275                 280                 285             


Leu Ser Glu Pro Tyr Ser Gln Cys Thr Glu Asp Gly Ser Asp Val Pro 
    290                 295                 300                 


Ile Arg Asn Ile Tyr Asn Ala Ala Tyr Ser Leu Gln Ile Cys Leu His 
305                 310                 315                 320 


Ser Cys Phe Gln Thr Lys Met Val Glu Lys Cys Gly Cys Ala Gln Tyr 
                325                 330                 335     


Ser Gln Pro Leu Pro Pro Ala Ala Asn Tyr Cys Asn Tyr Gln Gln His 
            340                 345                 350         


Pro Asn Trp Met Tyr Cys Tyr Tyr Gln Leu His Arg Ala Phe Val Gln 
        355                 360                 365             


Glu Glu Leu Gly Cys Gln Ser Val Cys Lys Glu Ala Cys Ser Phe Lys 
    370                 375                 380                 


Glu Trp Thr Leu Thr Thr Ser Leu Ala Gln Trp Pro Ser Val Val Ser 
385                 390                 395                 400 


Glu Lys Trp Leu Leu Pro Val Leu Thr Trp Asp Gln Gly Arg Gln Val 
                405                 410                 415     


Asn Lys Lys Leu Asn Lys Thr Asp Leu Ala Lys Leu Leu Ile Phe Tyr 
            420                 425                 430         


Lys Asp Leu Asn Gln Arg Ser Ile Met Glu Ser Pro Ala Asn Ser Ile 
        435                 440                 445             


Glu Met Leu Leu Ser Asn Phe Gly Gly Gln Leu Gly Leu Trp Met Ser 
    450                 455                 460                 


Cys 
465 


<210>  2272
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  2272

Tyr Glu Lys Gly Tyr Gln Thr Ser Ser Gly Leu Ile Ser Ser Val Ser 
1               5                   10                  15      


Val Lys Leu Lys Gly Leu Ala Val Thr Gln Leu Pro Gly Leu Gly Pro 
            20                  25                  30          


Gln Val Trp Asp Val Ala Asp Tyr Val Phe Pro Ala Gln Gly Asp Asn 
        35                  40                  45              


Ser Phe Val Val Met Thr Asn Phe Ile Val Thr Pro Lys Gln Thr Gln 
    50                  55                  60                  


Gly Tyr Cys Ala Glu His Pro Glu Gly Gly Ile Cys Lys Glu Asp Ser 
65                  70                  75                  80  


Gly Cys Thr Pro Gly Lys Ala Lys Arg Lys Ala Gln Gly Ile Arg Thr 
                85                  90                  95      


Gly Lys Cys Val Ala Phe Asn Asp Thr Val Lys Thr Cys Glu Ile Phe 
            100                 105                 110         


Gly Trp Cys Pro Val Glu Val Asp Asp Asp Ile Pro Arg Pro Ala Leu 
        115                 120                 125             


Leu Arg Glu Ala Glu Asn Phe Thr Leu Phe Ile Lys Asn Ser Ile Ser 
    130                 135                 140                 


Phe Pro Arg Phe Lys Val Asn Arg Arg Asn Leu Val Glu Glu Val Asn 
145                 150                 155                 160 


Ala Ala His Met Lys Thr Cys Leu Phe His Lys Thr Leu His Pro Leu 
                165                 170                 175     


Cys Pro Val Phe Gln Leu Gly Tyr Val Val Gln Glu Ser Gly Gln Asn 
            180                 185                 190         


Phe Ser Thr Leu Ala Glu Lys Gly Gly Val Val Gly Ile Thr Ile Asp 
        195                 200                 205             


Trp His Cys Asp Leu Asp Trp His Val Arg His Cys Arg Pro Ile Tyr 
    210                 215                 220                 


Glu Phe His Gly Leu Tyr Glu Glu Lys Asn Leu Ser Pro Gly Phe Asn 
225                 230                 235                 240 


Phe Arg Phe Ala Arg His Phe Val Glu Asn Gly Thr Asn Tyr Arg His 
                245                 250                 255     


Leu Phe Lys Val Phe Gly Ile Arg Phe Asp Ile Leu Val Asp Gly Lys 
            260                 265                 270         


Ala Gly Lys Phe Asp Ile Ile Pro Thr Met Thr Thr Ile Gly Ser Gly 
        275                 280                 285             


<210>  2273
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  2273

Gln Pro Pro Pro Pro Pro Pro Asp Ala Thr Cys His Gln Val Arg Ser 
1               5                   10                  15      


Phe Phe Gln Arg Leu Gln Pro Gly Leu Lys Trp Val Pro Glu Thr Pro 
            20                  25                  30          


Val Pro Gly Ser Asp Leu Gln Val Cys Leu Pro Lys Gly Pro Thr Cys 
        35                  40                  45              


Cys Ser Arg Lys Met Glu Glu Lys Tyr Gln Leu Thr Ala Arg Leu Asn 
    50                  55                  60                  


Met Glu Gln Leu Leu Gln Ser Ala Ser Met Glu Leu Lys Phe Leu Ile 
65                  70                  75                  80  


Ile Gln Asn Ala Ala Val Phe Gln Glu Ala Phe Glu Ile Val Val Arg 
                85                  90                  95      


His Ala Lys Asn Tyr Thr Asn Ala Met Phe Lys Asn Asn Tyr Pro Ser 
            100                 105                 110         


Leu Thr Pro Gln Ala Phe Glu Phe Val Gly Glu Phe Phe Thr Asp Val 
        115                 120                 125             


Ser Leu Tyr Ile Leu Gly Ser Asp Ile Asn Val Asp Asp Met Val Asn 
    130                 135                 140                 


Glu Leu Phe Asp Ser Leu Phe Pro Val Ile Tyr Thr Gln Leu Met Asn 
145                 150                 155                 160 


Pro Gly Leu Pro Asp Ser Ala Leu Asp Ile Asn Glu Cys Leu Arg Gly 
                165                 170                 175     


Ala Arg Arg Asp Leu Lys Val Phe Gly Asn Phe Pro Lys Leu Ile Met 
            180                 185                 190         


Thr Gln Val Ser Lys Ser Leu Gln Val Thr Arg Ile Phe Leu Gln Ala 
        195                 200                 205             


Leu Asn Leu Gly Ile Glu Val Ile Asn Thr Thr Asp His Leu Lys Phe 
    210                 215                 220                 


Ser Lys Asp Cys Gly Arg Met Leu Thr Arg Met Trp Tyr Cys Ser Tyr 
225                 230                 235                 240 


Cys Gln Gly Leu Met Met Val Lys Pro Cys Gly Gly Tyr Cys Asn Val 
                245                 250                 255     


Val Met Gln Gly Cys Met Ala Gly Val Val Glu Ile Asp Lys Tyr Trp 
            260                 265                 270         


Arg Glu Tyr Ile Leu Ser Leu Glu Glu Leu Val Asn Gly Met Tyr Arg 
        275                 280                 285             


Ile Tyr Asp Met Glu Asn Val Leu Leu Gly Leu Phe Ser Thr Ile His 
    290                 295                 300                 


Asp Ser Ile Gln Tyr Val Gln Lys Asn Ala Gly Lys Leu Thr Thr Thr 
305                 310                 315                 320 


Ile Gly Lys Leu Cys Ala His Ser Gln Gln Arg Gln Tyr Arg Phe Ala 
                325                 330                 335     


Tyr Tyr Pro Glu Asp Leu Phe Ile Asp Lys Lys Val Leu Lys Val Ala 
            340                 345                 350         


His Val Glu His Glu Glu Thr Leu Ser Ser Arg Arg Arg Glu Leu Ile 
        355                 360                 365             


Gln Lys Leu Lys Ser Phe Ile Ser Phe Tyr Ser Ala Leu Pro Gly Tyr 
    370                 375                 380                 


Ile Cys Ser His Ser Pro Val Ala Glu Asn Asp Thr Leu Cys Trp Asn 
385                 390                 395                 400 


Gly Gln Glu Leu Val Glu Arg Tyr Ser Gln Lys Ala Ala Arg Asn Gly 
                405                 410                 415     


Met Lys Asn Gln Phe Asn Leu His Glu Leu Lys Met Lys Gly Pro Glu 
            420                 425                 430         


Pro Val Val Ser Gln Ile Ile Asp Lys Leu Lys His Ile Asn Gln Leu 
        435                 440                 445             


Leu Arg Thr Met Ser Met Pro Lys Gly Arg Val Leu Asp Lys Asn Leu 
    450                 455                 460                 


Asp Glu Glu Gly Phe Glu Ser Gly Asp Cys Gly Asp Asp Glu Asp Glu 
465                 470                 475                 480 


Cys Ile Gly Gly Ser Gly Asp Gly Met Ile Lys Val Lys Asn Gln Leu 
                485                 490                 495     


Arg Phe Leu Ala Glu Leu Ala Tyr Asp Leu Asp Val Asp Asp Ala Pro 
            500                 505                 510         


Gly Asn Ser Gln Gln Ala Thr Pro Lys Asp Asn Glu Ile Ser Thr Phe 
        515                 520                 525             


His Asn Leu Gly Asn Val His Ser Pro Leu Lys Leu Leu Thr 
    530                 535                 540         


<210>  2274
<211>  65
<212>  PRT
<213>  Homo Sapiens

<400>  2274

Ser Leu Pro Val Tyr Met Tyr Phe Asn Leu Trp Thr Ile Cys Arg Asn 
1               5                   10                  15      


Thr Thr Leu Val Glu Gly Ala Asn Leu Cys Leu Asp Leu Arg Gln Phe 
            20                  25                  30          


Gly Ile Val Thr Ile Gly Glu Glu Lys Lys Ile Cys Thr Val Ser Glu 
        35                  40                  45              


Asn Phe Leu Arg Met Cys Glu Ser Thr Glu Leu Asn Met Thr Phe His 
    50                  55                  60                  


Leu 
65  


<210>  2275
<211>  48
<212>  PRT
<213>  Homo Sapiens

<400>  2275

Met Thr Pro Thr Asp Phe Thr Ser Pro Ile Pro Asn Met Ala Asp Asp 
1               5                   10                  15      


Tyr Gly Ser Glu Ser Thr Ser Ser Met Glu Asp Tyr Val Asn Phe Asn 
            20                  25                  30          


Phe Thr Asp Phe Tyr Cys Glu Lys Asn Asn Val Arg Gln Phe Ala Ser 
        35                  40                  45              


<210>  2276
<211>  482
<212>  PRT
<213>  Homo Sapiens

<400>  2276

Arg Pro Arg Asn Ala Leu Leu Leu Leu Ala Asp Asp Gly Gly Phe Glu 
1               5                   10                  15      


Ser Gly Ala Tyr Asn Asn Ser Ala Ile Ala Thr Pro His Leu Asp Ala 
            20                  25                  30          


Leu Ala Arg Arg Ser Leu Leu Phe Arg Asn Ala Phe Thr Ser Val Ser 
        35                  40                  45              


Ser Cys Ser Pro Ser Arg Ala Ser Leu Leu Thr Gly Leu Pro Gln His 
    50                  55                  60                  


Gln Asn Gly Met Tyr Gly Leu His Gln Asp Val His His Phe Asn Ser 
65                  70                  75                  80  


Phe Asp Lys Val Arg Ser Leu Pro Leu Leu Leu Ser Gln Ala Gly Val 
                85                  90                  95      


Arg Thr Gly Ile Ile Gly Lys Lys His Val Gly Pro Glu Thr Val Tyr 
            100                 105                 110         


Pro Phe Asp Phe Ala Tyr Thr Glu Glu Asn Gly Ser Val Leu Gln Val 
        115                 120                 125             


Gly Arg Asn Ile Thr Arg Ile Lys Leu Leu Val Arg Lys Phe Leu Gln 
    130                 135                 140                 


Thr Gln Asp Asp Arg Pro Phe Phe Leu Tyr Val Ala Phe His Asp Pro 
145                 150                 155                 160 


His Arg Cys Gly His Ser Gln Pro Gln Tyr Gly Thr Phe Cys Glu Lys 
                165                 170                 175     


Phe Gly Asn Gly Glu Ser Gly Met Gly Arg Ile Pro Asp Trp Thr Pro 
            180                 185                 190         


Gln Ala Tyr Asp Pro Leu Asp Val Leu Val Pro Tyr Phe Val Pro Asn 
        195                 200                 205             


Thr Pro Ala Ala Arg Ala Asp Leu Ala Ala Gln Tyr Thr Thr Val Gly 
    210                 215                 220                 


Arg Met Asp Gln Gly Val Gly Leu Val Leu Gln Glu Leu Arg Asp Ala 
225                 230                 235                 240 


Gly Val Leu Asn Asp Thr Leu Val Ile Phe Thr Ser Asp Asn Gly Ile 
                245                 250                 255     


Pro Phe Pro Ser Gly Arg Thr Asn Leu Tyr Trp Pro Gly Thr Ala Glu 
            260                 265                 270         


Pro Leu Leu Val Ser Ser Pro Glu His Pro Lys Arg Trp Gly Gln Val 
        275                 280                 285             


Ser Glu Ala Tyr Val Ser Leu Leu Asp Leu Thr Pro Thr Ile Leu Asp 
    290                 295                 300                 


Trp Phe Ser Ile Pro Tyr Pro Ser Tyr Ala Ile Phe Gly Ser Lys Thr 
305                 310                 315                 320 


Ile His Leu Thr Gly Arg Ser Leu Leu Pro Ala Leu Glu Ala Glu Pro 
                325                 330                 335     


Leu Trp Ala Thr Val Phe Gly Ser Gln Ser His His Glu Val Thr Met 
            340                 345                 350         


Ser Tyr Pro Met Arg Ser Val Gln His Arg His Phe Arg Leu Val His 
        355                 360                 365             


Asn Leu Asn Phe Lys Met Pro Phe Pro Ile Asp Gln Asp Phe Tyr Val 
    370                 375                 380                 


Ser Pro Thr Phe Gln Asp Leu Leu Asn Arg Thr Thr Ala Gly Gln Pro 
385                 390                 395                 400 


Thr Gly Trp Tyr Lys Asp Leu Arg His Tyr Tyr Tyr Arg Ala Arg Trp 
                405                 410                 415     


Glu Leu Tyr Asp Arg Ser Arg Asp Pro His Glu Thr Gln Asn Leu Ala 
            420                 425                 430         


Thr Asp Pro Arg Phe Ala Gln Leu Leu Glu Met Leu Arg Asp Gln Leu 
        435                 440                 445             


Ala Lys Trp Gln Trp Glu Thr His Asp Pro Trp Val Cys Ala Pro Asp 
    450                 455                 460                 


Gly Val Leu Glu Glu Lys Leu Ser Pro Gln Cys Gln Pro Leu His Asn 
465                 470                 475                 480 


Glu Leu 
        


<210>  2277
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  2277

Lys Thr Ala Asn Ala Phe Lys Pro Asn Ile Leu Leu Ile Met Ala Asp 
1               5                   10                  15      


Asp Leu Gly Thr Gly Asp Leu Gly Cys Tyr Gly Asn Asn Thr Leu Arg 
            20                  25                  30          


Thr Pro Asn Ile Asp Gln Leu Ala Glu Glu Gly Val Arg Leu Thr Gln 
        35                  40                  45              


His Leu Ala Ala Ala Pro Leu Cys Thr Pro Ser Arg Ala Ala Phe Leu 
    50                  55                  60                  


Thr Gly Arg His Ser Phe Arg Ser Gly Met Asp Ala Ser Asn Gly Tyr 
65                  70                  75                  80  


Arg Ala Leu Gln Trp Asn Ala Gly Ser Gly Gly Leu Pro Glu Asn Glu 
                85                  90                  95      


Thr Thr Phe Ala Arg Ile Leu Gln Gln His Gly Tyr Ala Thr Gly Leu 
            100                 105                 110         


Ile Gly Lys Trp His Gln Gly Val Asn Cys Ala Ser Arg Gly Asp His 
        115                 120                 125             


Cys His His Pro Leu Asn His Gly Phe Asp Tyr Phe Tyr Gly Met Pro 
    130                 135                 140                 


Phe Thr Leu Thr Asn Asp Cys Asp Pro Gly Arg Pro Pro Glu Val Asp 
145                 150                 155                 160 


Ala Ala Leu Arg Ala Gln Leu Trp Gly Tyr Thr Gln Phe Leu Ala Leu 
                165                 170                 175     


Gly Ile Leu Thr Leu Ala Ala Gly Gln Thr Cys Gly Phe Phe Ser Val 
            180                 185                 190         


Ser Ala Arg Ala Val Thr Gly Met Ala Gly Val Gly Cys Leu Phe Phe 
        195                 200                 205             


Ile Ser Trp Tyr Ser Ser Phe Gly Phe Val Arg Arg Trp Asn Cys Ile 
    210                 215                 220                 


Leu Met Arg Asn His Asp Val Thr Glu Gln Pro Met Val Leu Glu Lys 
225                 230                 235                 240 


Thr Ala Ser Leu Met Leu Lys Glu Ala Val Ser Tyr Ile Glu Arg His 
                245                 250                 255     


Lys His Gly Pro Phe Leu Leu Phe Leu Ser Leu Leu His Val His Ile 
            260                 265                 270         


Pro Leu Val Thr Thr Ser Ala Phe Leu Gly Lys Ser Gln His Gly Leu 
        275                 280                 285             


Tyr Gly Asp Asn Val Glu Glu Met Asp Trp Leu Ile Gly Lys Val Leu 
    290                 295                 300                 


Asn Ala Ile Glu Asp Asn Gly Leu Lys Asn Ser Thr Phe Thr Tyr Phe 
305                 310                 315                 320 


Thr Ser Asp His Gly Gly His Leu Glu Ala Arg Asp Gly His Ser Gln 
                325                 330                 335     


Leu Gly Gly Trp Asn Gly Ile Tyr Lys Gly Gly Lys Gly Met Gly Gly 
            340                 345                 350         


Trp Glu Gly Gly Ile Arg Val Pro Gly Ile Phe His Trp Pro Gly Val 
        355                 360                 365             


Leu Pro Ala Gly Arg Val Ile Gly Glu Pro Thr Ser Leu Met Asp Val 
    370                 375                 380                 


Phe Pro Thr Val Val Gln Leu Val Gly Gly Glu Val Pro Gln Asp Arg 
385                 390                 395                 400 


Val Ile Asp Gly His Ser Leu Val Pro Leu Leu Gln Gly Ala Glu Ala 
                405                 410                 415     


Arg Ser Ala His Glu Phe Leu Phe His Tyr Cys Gly Gln His Leu His 
            420                 425                 430         


Ala Ala Arg Trp His Gln Lys Asp Ser Gly Ser Val Trp Lys Val His 
        435                 440                 445             


Tyr Thr Thr Pro Gln Phe His Pro Glu Gly Ala Gly Ala Cys Tyr Gly 
    450                 455                 460                 


Arg Gly Val Cys Pro Cys Ser Gly Glu Gly Val Thr His His Arg Pro 
465                 470                 475                 480 


Pro Leu Leu Phe Asp Leu Ser Arg Asp Pro Ser Glu Ala Arg Pro Leu 
                485                 490                 495     


Thr Pro Asp Ser Glu Pro Leu Tyr His Ala Val Ile Ala Arg Val Gly 
            500                 505                 510         


Ala Ala Val Ser Glu His Arg Gln Thr Leu Ser Pro Val Pro Gln Gln 
        515                 520                 525             


Phe Ser Met Ser Asn Ile Leu Trp Lys Pro Trp Leu Gln Pro Cys Cys 
    530                 535                 540                 


Gly His Phe Pro Phe Cys Ser Cys His Glu Asp Gly Asp Gly Thr Pro 
545                 550                 555                 560 


<210>  2278
<211>  558
<212>  PRT
<213>  Homo Sapiens

<400>  2278

Asp Ile Ser Ala Ser Arg Pro Asn Ile Leu Leu Leu Met Ala Asp Asp 
1               5                   10                  15      


Leu Gly Ile Gly Asp Val Gly Cys Tyr Gly Asn Asn Thr Met Arg Thr 
            20                  25                  30          


Pro Asn Ile Asp Arg Leu Ala Glu Asp Gly Val Lys Leu Thr Gln His 
        35                  40                  45              


Ile Ser Ala Ala Ser Leu Cys Thr Pro Ser Arg Ala Ala Phe Leu Thr 
    50                  55                  60                  


Gly Arg Tyr Pro Val Arg Ser Gly Met Val Ser Ser Ile Gly Tyr Arg 
65                  70                  75                  80  


Val Leu Gln Trp Thr Gly Ala Ser Gly Gly Leu Pro Thr Asn Glu Thr 
                85                  90                  95      


Thr Phe Ala Lys Ile Leu Lys Glu Lys Gly Tyr Ala Thr Gly Leu Ile 
            100                 105                 110         


Gly Lys Trp His Leu Gly Leu Asn Cys Glu Ser Ala Ser Asp His Cys 
        115                 120                 125             


His His Pro Leu His His Gly Phe Asp His Phe Tyr Gly Met Pro Phe 
    130                 135                 140                 


Ser Leu Met Gly Asp Cys Ala Arg Trp Glu Leu Ser Glu Lys Arg Val 
145                 150                 155                 160 


Asn Leu Glu Gln Lys Leu Asn Phe Leu Phe Gln Val Leu Ala Leu Val 
                165                 170                 175     


Ala Leu Thr Leu Val Ala Gly Lys Leu Thr His Leu Ile Pro Val Ser 
            180                 185                 190         


Trp Met Pro Val Ile Trp Ser Ala Leu Ser Ala Val Leu Leu Leu Ala 
        195                 200                 205             


Ser Ser Tyr Phe Val Gly Ala Leu Ile Val His Ala Asp Cys Phe Leu 
    210                 215                 220                 


Met Arg Asn His Thr Ile Thr Glu Gln Pro Met Cys Phe Gln Arg Thr 
225                 230                 235                 240 


Thr Pro Leu Ile Leu Gln Glu Val Ala Ser Phe Leu Lys Arg Asn Lys 
                245                 250                 255     


His Gly Pro Phe Leu Leu Phe Val Ser Phe Leu His Val His Ile Pro 
            260                 265                 270         


Leu Ile Thr Met Glu Asn Phe Leu Gly Lys Ser Leu His Gly Leu Tyr 
        275                 280                 285             


Gly Asp Asn Val Glu Glu Met Asp Trp Met Val Gly Arg Ile Leu Asp 
    290                 295                 300                 


Thr Leu Asp Val Glu Gly Leu Ser Asn Ser Thr Leu Ile Tyr Phe Thr 
305                 310                 315                 320 


Ser Asp His Gly Gly Ser Leu Glu Asn Gln Leu Gly Asn Thr Gln Tyr 
                325                 330                 335     


Gly Gly Trp Asn Gly Ile Tyr Lys Gly Gly Lys Gly Met Gly Gly Trp 
            340                 345                 350         


Glu Gly Gly Ile Arg Val Pro Gly Ile Phe Arg Trp Pro Gly Val Leu 
        355                 360                 365             


Pro Ala Gly Arg Val Ile Gly Glu Pro Thr Ser Leu Met Asp Val Phe 
    370                 375                 380                 


Pro Thr Val Val Arg Leu Ala Gly Gly Glu Val Pro Gln Asp Arg Val 
385                 390                 395                 400 


Ile Asp Gly Gln Asp Leu Leu Pro Leu Leu Leu Gly Thr Ala Gln His 
                405                 410                 415     


Ser Asp His Glu Phe Leu Met His Tyr Cys Glu Arg Phe Leu His Ala 
            420                 425                 430         


Ala Arg Trp His Gln Arg Asp Arg Gly Thr Met Trp Lys Val His Phe 
        435                 440                 445             


Val Thr Pro Val Phe Gln Pro Glu Gly Ala Gly Ala Cys Tyr Gly Arg 
    450                 455                 460                 


Lys Val Cys Pro Cys Phe Gly Glu Lys Val Val His His Asp Pro Pro 
465                 470                 475                 480 


Leu Leu Phe Asp Leu Ser Arg Asp Pro Ser Glu Thr His Ile Leu Thr 
                485                 490                 495     


Pro Ala Ser Glu Pro Val Phe Tyr Gln Val Met Glu Arg Val Gln Gln 
            500                 505                 510         


Ala Val Trp Glu His Gln Arg Thr Leu Ser Pro Val Pro Leu Gln Leu 
        515                 520                 525             


Asp Arg Leu Gly Asn Ile Trp Arg Pro Trp Leu Gln Pro Cys Cys Gly 
    530                 535                 540                 


Pro Phe Pro Leu Cys Trp Cys Leu Arg Glu Asp Asp Pro Gln 
545                 550                 555             


<210>  2279
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  2279

Ser Leu Ala Gly Gly Ser Pro Gly Ala Ala Glu Ala Pro Gly Ser Ala 
1               5                   10                  15      


Gln Val Ala Gly Leu Cys Gly Arg Leu Thr Leu His Arg Asp Leu Arg 
            20                  25                  30          


Thr Gly Arg Trp Glu Pro Asp Pro Gln Arg Ser Arg Arg Cys Leu Arg 
        35                  40                  45              


Asp Pro Gln Arg Val Leu Glu Tyr Cys Arg Gln Met Tyr Pro Glu Leu 
    50                  55                  60                  


Gln Ile Ala Arg Val Glu Gln Ala Thr Gln Ala Ile Pro Met Glu Arg 
65                  70                  75                  80  


Trp Cys Gly Gly Ser Arg Ser Gly Ser Cys Ala His Pro His His Gln 
                85                  90                  95      


Val Val Pro Phe Arg Cys Leu Pro Gly Glu Phe Val Ser Glu Ala Leu 
            100                 105                 110         


Leu Val Pro Glu Gly Cys Arg Phe Leu His Gln Glu Arg Met Asp Gln 
        115                 120                 125             


Cys Glu Ser Ser Thr Arg Arg His Gln Glu Ala Gln Glu Ala Cys Ser 
    130                 135                 140                 


Ser Gln Gly Leu Ile Leu His Gly Ser Gly Met Leu Leu Pro Cys Gly 
145                 150                 155                 160 


Ser Asp Arg Phe Arg Gly Val Glu Tyr Val Cys Cys Pro Pro Pro Gly 
                165                 170                 175     


Thr Pro Asp Pro Ser Gly Thr Ala Val Gly Asp Pro Ser Thr Arg Ser 
            180                 185                 190         


Trp Pro Pro Gly Ser Arg Val Glu Gly Ala Glu Asp Glu Glu Glu Glu 
        195                 200                 205             


Glu Ser Phe Pro Gln Pro Val Asp Asp Tyr Phe Val Glu Pro Pro Gln 
    210                 215                 220                 


Ala Glu Glu Glu Glu Glu Thr Val Pro Pro Pro Ser Ser His Thr Leu 
225                 230                 235                 240 


Ala Val Val Gly Lys Val Thr Pro Thr Pro Arg Pro Thr Asp Gly Val 
                245                 250                 255     


Asp Ile Tyr Phe Gly Met Pro Gly Glu Ile Ser Glu His Glu Gly Phe 
            260                 265                 270         


Leu Arg Ala Lys Met Asp Leu Glu Glu Arg Arg Met Arg Gln Ile Asn 
        275                 280                 285             


Glu Val Met Arg Glu Trp Ala Met Ala Asp Asn Gln Ser Lys Asn Leu 
    290                 295                 300                 


Pro Lys Ala Asp Arg Gln Ala Leu Asn Glu His Phe Gln Ser Ile Leu 
305                 310                 315                 320 


Gln Thr Leu Glu Glu Gln Val Ser Gly Glu Arg Gln Arg Leu Val Glu 
                325                 330                 335     


Thr His Ala Thr Arg Val Ile Ala Leu Ile Asn Asp Gln Arg Arg Ala 
            340                 345                 350         


Ala Leu Glu Gly Phe Leu Ala Ala Leu Gln Ala Asp Pro Pro Gln Ala 
        355                 360                 365             


Glu Arg Val Leu Leu Ala Leu Arg Arg Tyr Leu Arg Ala Glu Gln Lys 
    370                 375                 380                 


Glu Gln Arg His Thr Leu Arg His Tyr Gln His Val Ala Ala Val Asp 
385                 390                 395                 400 


Pro Glu Lys Ala Gln Gln Met Arg Phe Gln Val His Thr His Leu Gln 
                405                 410                 415     


Val Ile Glu Glu Arg Val Asn Gln Ser Leu Gly Leu Leu Asp Gln Asn 
            420                 425                 430         


Pro His Leu Ala Gln Glu Leu Arg Pro Gln Ile Gln Glu Leu Leu His 
        435                 440                 445             


Ser Glu His Leu Gly Pro Ser Glu Leu Glu Ala Pro Ala Pro Gly Gly 
    450                 455                 460                 


Ser Ser Glu Asp Lys Gly Gly Leu Gln Pro Pro Asp Ser Lys Asp Asp 
465                 470                 475                 480 


Thr Pro Met Thr Leu Pro Lys Gly Ser Thr Glu Gln Asp Ala Ala Ser 
                485                 490                 495     


Pro Glu Lys Glu Lys Met Asn Pro Leu Glu Gln Tyr Glu Arg Lys Val 
            500                 505                 510         


Asn Ala Ser Val Pro Arg Gly Phe Pro Phe His Ser Ser Glu Ile Gln 
        515                 520                 525             


Arg Asp Glu Leu Ala Pro Ala Gly Thr Gly Val Ser Arg Glu 
    530                 535                 540         


<210>  2280
<211>  51
<212>  PRT
<213>  Homo Sapiens

<400>  2280

Tyr Phe Gln Ser Gly Asn Asn Glu Glu Pro Tyr Val Ser Ile Thr Lys 
1               5                   10                  15      


Lys Arg Gln Met Pro Lys Asn Gly Leu Ser Glu Glu Ile Glu Lys Glu 
            20                  25                  30          


Val Gly Gln Ala Glu Gly Lys Leu Ile Thr His Arg Ser Ala Phe Ser 
        35                  40                  45              


Arg Ala Ser 
    50      


<210>  2281
<211>  417
<212>  PRT
<213>  Homo Sapiens

<400>  2281

Leu Pro Tyr Lys Ile Gly Val Val Gly Pro Trp Ala Cys Asp Ser Leu 
1               5                   10                  15      


Phe Ser Lys Ala Leu Pro Glu Val Ala Ala Arg Leu Ala Ile Glu Arg 
            20                  25                  30          


Ile Asn Arg Asp Pro Ser Phe Asp Leu Ser Tyr Ser Phe Glu Tyr Val 
        35                  40                  45              


Ile Leu Asn Glu Asp Cys Gln Thr Ser Arg Ala Leu Ser Ser Phe Ile 
    50                  55                  60                  


Ser His His Gln Met Ala Ser Gly Phe Ile Gly Pro Thr Asn Pro Gly 
65                  70                  75                  80  


Tyr Cys Glu Ala Ala Ser Leu Leu Gly Asn Ser Trp Asp Lys Gly Ile 
                85                  90                  95      


Phe Ser Trp Ala Cys Val Asn Tyr Glu Leu Asp Asn Lys Ile Ser Tyr 
            100                 105                 110         


Pro Thr Phe Ser Arg Thr Leu Pro Ser Pro Ile Arg Val Leu Val Thr 
        115                 120                 125             


Val Met Lys Tyr Phe Gln Trp Ala His Ala Gly Val Ile Ser Ser Asp 
    130                 135                 140                 


Glu Asp Ile Trp Val His Thr Ala Asn Arg Val Ala Ser Ala Leu Arg 
145                 150                 155                 160 


Ser His Gly Leu Pro Val Gly Val Val Leu Thr Thr Gly Gln Asp Ser 
                165                 170                 175     


Gln Ser Met Arg Lys Ala Leu Gln Arg Ile His Gln Ala Asp Arg Ile 
            180                 185                 190         


Arg Ile Ile Ile Met Cys Met His Ser Ala Leu Ile Gly Gly Glu Thr 
        195                 200                 205             


Gln Met His Leu Leu Glu Cys Ala His Asp Leu Lys Met Thr Asp Gly 
    210                 215                 220                 


Thr Tyr Val Phe Val Pro Tyr Asp Ala Leu Leu Tyr Ser Leu Pro Tyr 
225                 230                 235                 240 


Lys His Thr Pro Tyr Arg Val Leu Arg Asn Asn Pro Lys Leu Arg Glu 
                245                 250                 255     


Ala Tyr Asp Ala Val Leu Thr Ile Thr Val Glu Ser Gln Glu Lys Thr 
            260                 265                 270         


Phe Tyr Gln Ala Phe Thr Glu Ala Ala Ala Arg Gly Glu Ile Pro Glu 
        275                 280                 285             


Lys Leu Glu Phe Asp Gln Val Ser Pro Leu Phe Gly Thr Ile Tyr Asn 
    290                 295                 300                 


Ser Ile Tyr Phe Ile Ala Gln Ala Met Asn Asn Ala Met Lys Glu Asn 
305                 310                 315                 320 


Gly Gln Ala Gly Ala Ala Ser Leu Val Gln His Ser Arg Asn Met Gln 
                325                 330                 335     


Phe His Gly Phe Asn Gln Leu Met Arg Thr Asp Ser Asn Gly Asn Gly 
            340                 345                 350         


Ile Ser Glu Tyr Val Ile Leu Asp Thr Asn Leu Lys Glu Trp Glu Leu 
        355                 360                 365             


His Ser Thr Tyr Thr Val Asp Met Glu Met Glu Leu Leu Arg Phe Gly 
    370                 375                 380                 


Gly Thr Pro Ile His Phe Pro Gly Gly Arg Pro Pro Arg Ala Asp Ala 
385                 390                 395                 400 


Lys Cys Trp Phe Ala Glu Gly Lys Ile Cys His Gly Gly Ile Asp Pro 
                405                 410                 415     


Ala 
    


<210>  2282
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  2282

Val Ala Ala Gln Asn Ser Ala Glu Val Val Arg Cys Leu Asn Ser Ala 
1               5                   10                  15      


Leu Gln Val Gly Cys Gly Ala Phe Ala Cys Leu Glu Asn Ser Thr Cys 
            20                  25                  30          


Asp Thr Asp Gly Met Tyr Asp Ile Cys Lys Ser Phe Leu Tyr Ser Ala 
        35                  40                  45              


Ala Lys Phe Asp Thr Gln Gly Lys Ala Phe Val Lys Glu Ser Leu Lys 
    50                  55                  60                  


Cys Ile Ala Asn Gly Val Thr Ser Lys Val Phe Leu Ala Ile Arg Arg 
65                  70                  75                  80  


Cys Ser Thr Phe Gln Arg Met Ile Ala Glu Val Gln Glu Glu Cys Tyr 
                85                  90                  95      


Ser Lys Leu Asn Val Cys Ser Ile Ala Lys Arg Asn Pro Glu Ala Ile 
            100                 105                 110         


Thr Glu Val Val Gln Leu Pro Asn His Phe Ser Asn Arg Tyr Tyr Asn 
        115                 120                 125             


Arg Leu Val Arg Ser Leu Leu Glu Cys Asp Glu Asp Thr Val Ser Thr 
    130                 135                 140                 


Ile Arg Asp Ser Leu Met Glu Lys Ile Gly Pro Asn Met Ala Ser Leu 
145                 150                 155                 160 


Phe His Ile Leu Gln Thr Asp His Cys Ala Gln Thr His Pro Arg Ala 
                165                 170                 175     


Asp Phe Asn Arg Arg Arg Thr Asn Glu Pro Gln Lys Leu Lys Val Leu 
            180                 185                 190         


Leu Arg Asn Leu Arg Gly Glu Glu Asp Ser Pro Ser His Ile Lys Arg 
        195                 200                 205             


Thr Ser His Glu Ser Ala 
    210                 


<210>  2283
<211>  273
<212>  PRT
<213>  Homo Sapiens

<400>  2283

Gln Ser His Pro Ile Thr Arg Arg Asp Leu Phe Ser Gln Glu Ile Gln 
1               5                   10                  15      


Leu Asp Met Ala Leu Ala Ser Phe Asp Asp Gln Tyr Ala Gly Cys Ala 
            20                  25                  30          


Ala Ala Met Thr Ala Ala Leu Pro Asp Leu Asn His Thr Glu Phe Gln 
        35                  40                  45              


Ala Asn Gln Val Tyr Ala Asp Ser Trp Thr Leu Ala Ser Ser Gln Trp 
    50                  55                  60                  


Gln Glu Arg Gln Ala Arg Trp Pro Glu Trp Ser Leu Ser Pro Thr Arg 
65                  70                  75                  80  


Pro Ser Pro Pro Pro Leu Gly Phe Arg Asp Glu His Gly Val Ala Leu 
                85                  90                  95      


Leu Ala Tyr Thr Ala Asn Ser Pro Leu His Lys Glu Phe Asn Ala Ala 
            100                 105                 110         


Val Arg Glu Ala Gly Arg Ser Arg Ala His Tyr Leu His His Phe Ser 
        115                 120                 125             


Phe Lys Thr Leu His Phe Leu Leu Thr Glu Ala Leu Gln Leu Leu Gly 
    130                 135                 140                 


Ser Gly Gln Arg Pro Pro Arg Cys His Gln Val Phe Arg Gly Val His 
145                 150                 155                 160 


Gly Leu Arg Phe Arg Pro Ala Gly Pro Arg Ala Thr Val Arg Leu Gly 
                165                 170                 175     


Gly Phe Ala Ser Ala Ser Leu Lys His Val Ala Ala Gln Gln Phe Gly 
            180                 185                 190         


Glu Asp Thr Phe Phe Gly Ile Trp Thr Cys Leu Gly Ala Pro Ile Lys 
        195                 200                 205             


Gly Tyr Ser Phe Phe Pro Gly Glu Glu Glu Val Leu Ile Pro Pro Phe 
    210                 215                 220                 


Glu Thr Phe Gln Val Ile Asn Ala Ser Arg Leu Ala Gln Gly Pro Ala 
225                 230                 235                 240 


Arg Ile Tyr Leu Arg Ala Leu Gly Lys His Ser Thr Tyr Asn Cys Glu 
                245                 250                 255     


Tyr Ile Lys Asp Lys Lys Cys Lys Ser Gly Pro Cys His Leu Asp Asn 
            260                 265                 270         


Ser 
    


<210>  2284
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  2284

Asp Thr Pro Ala Asn Cys Thr Tyr Leu Asp Leu Leu Gly Thr Trp Val 
1               5                   10                  15      


Phe Gln Val Gly Ser Ser Gly Ser Gln Arg Asp Val Asn Cys Ser Val 
            20                  25                  30          


Met Gly Pro Gln Glu Lys Lys Val Val Val Tyr Leu Gln Lys Leu Asp 
        35                  40                  45              


Thr Ala Tyr Asp Asp Leu Gly Asn Ser Gly His Phe Thr Ile Ile Tyr 
    50                  55                  60                  


Asn Gln Gly Phe Glu Ile Val Leu Asn Asp Tyr Lys Trp Phe Ala Phe 
65                  70                  75                  80  


Phe Lys Tyr Lys Glu Glu Gly Ser Lys Val Thr Thr Tyr Cys Asn Glu 
                85                  90                  95      


Thr Met Thr Gly Trp Val His Asp Val Leu Gly Arg Asn Trp Ala Cys 
            100                 105                 110         


Phe Thr Gly Lys Lys Val Gly Thr Ala Ser Glu Asn Val Tyr Val Asn 
        115                 120                 125             


Thr Ala His Leu Lys Asn Ser Gln Glu Lys Tyr Ser Asn Arg Leu Tyr 
    130                 135                 140                 


Lys Tyr Asp His Asn Phe Val Lys Ala Ile Asn Ala Ile Gln Lys Ser 
145                 150                 155                 160 


Trp Thr Ala Thr Thr Tyr Met Glu Tyr Glu Thr Leu Thr Leu Gly Asp 
                165                 170                 175     


Met Ile Arg Arg Ser Gly Gly His Ser Arg Lys Ile Pro Arg Pro Lys 
            180                 185                 190         


Pro Ala Pro Leu Thr Ala Glu Ile Gln Gln Lys Ile Leu His Leu Pro 
        195                 200                 205             


Thr Ser Trp Asp Trp Arg Asn Val His Gly Ile Asn Phe Val Ser Pro 
    210                 215                 220                 


Val Arg Asn Gln Ala Ser Cys Gly Ser Cys Tyr Ser Phe Ala Ser Met 
225                 230                 235                 240 


Gly Met Leu Glu Ala Arg Ile Arg Ile Leu Thr Asn Asn Ser Gln Thr 
                245                 250                 255     


Pro Ile Leu Ser Pro Gln Glu Val Val Ser Cys Ser Gln Tyr Ala Gln 
            260                 265                 270         


Gly Cys Glu Gly Gly Phe Pro Tyr Leu Ile Ala Gly Lys Tyr Ala Gln 
        275                 280                 285             


Asp Phe Gly Leu Val Glu Glu Ala Cys Phe Pro Tyr Thr Gly Thr Asp 
    290                 295                 300                 


Ser Pro Cys Lys Met Lys Glu Asp Cys Phe Arg Tyr Tyr Ser Ser Glu 
305                 310                 315                 320 


Tyr His Tyr Val Gly Gly Phe Tyr Gly Gly Cys Asn Glu Ala Leu Met 
                325                 330                 335     


Lys Leu Glu Leu Val His His Gly Pro Met Ala Val Ala Phe Glu Val 
            340                 345                 350         


Tyr Asp Asp Phe Leu His Tyr Lys Lys Gly Ile Tyr His His Thr Gly 
        355                 360                 365             


Leu Arg Asp Pro Phe Asn Pro Phe Glu Leu Thr Asn His Ala Val Leu 
    370                 375                 380                 


Leu Val Gly Tyr Gly Thr Asp Ser Ala Ser Gly Met Asp Tyr Trp Ile 
385                 390                 395                 400 


Val Lys Asn Ser Trp Gly Thr Gly Trp Gly Glu Asn Gly Tyr Phe Arg 
                405                 410                 415     


Ile Arg Arg Gly Thr Asp Glu Cys Ala Ile Glu Ser Ile Ala Val Ala 
            420                 425                 430         


Ala Thr Pro Ile Pro Lys Leu 
        435                 


<210>  2285
<211>  64
<212>  PRT
<213>  Homo Sapiens

<400>  2285

Gln Glu Pro Pro Gly Ala Ala Cys Ser Gln Asn Thr Asn Lys Thr Cys 
1               5                   10                  15      


Glu Glu Cys Leu Lys Asn Val Ser Cys Leu Trp Cys Asn Thr Asn Lys 
            20                  25                  30          


Ala Cys Leu Asp Tyr Pro Val Thr Ser Val Leu Pro Pro Ala Ser Leu 
        35                  40                  45              


Cys Lys Leu Ser Ser Ala Arg Trp Gly Val Cys Trp Val Asn Phe Glu 
    50                  55                  60                  


<210>  2286
<211>  225
<212>  PRT
<213>  Homo Sapiens

<400>  2286

Asn Glu Asp Lys Asp Pro Ala Phe Thr Ala Leu Leu Thr Thr Gln Thr 
1               5                   10                  15      


Gln Val Gln Arg Glu Ile Val Asn Lys His Asn Glu Leu Arg Arg Ala 
            20                  25                  30          


Val Ser Pro Pro Ala Arg Asn Met Leu Lys Met Glu Trp Asn Lys Glu 
        35                  40                  45              


Ala Ala Ala Asn Ala Gln Lys Trp Ala Asn Gln Cys Asn Tyr Arg His 
    50                  55                  60                  


Ser Asn Pro Lys Asp Arg Met Thr Ser Leu Lys Cys Gly Glu Asn Leu 
65                  70                  75                  80  


Tyr Met Ser Ser Ala Ser Ser Ser Trp Ser Gln Ala Ile Gln Ser Trp 
                85                  90                  95      


Phe Asp Glu Tyr Asn Asp Phe Asp Phe Gly Val Gly Pro Lys Thr Pro 
            100                 105                 110         


Asn Ala Val Val Gly His Tyr Thr Gln Val Val Trp Tyr Ser Ser Tyr 
        115                 120                 125             


Leu Val Gly Cys Gly Asn Ala Tyr Cys Pro Asn Gln Lys Val Leu Lys 
    130                 135                 140                 


Tyr Tyr Tyr Val Cys Gln Tyr Cys Pro Ala Gly Asn Trp Ala Asn Arg 
145                 150                 155                 160 


Leu Tyr Val Pro Tyr Glu Gln Gly Ala Pro Cys Ala Ser Cys Pro Asp 
                165                 170                 175     


Asn Cys Asp Asp Gly Leu Cys Thr Asn Gly Cys Lys Tyr Glu Asp Leu 
            180                 185                 190         


Tyr Ser Asn Cys Lys Ser Leu Lys Leu Thr Leu Thr Cys Lys His Gln 
        195                 200                 205             


Leu Val Arg Asp Ser Cys Lys Ala Ser Cys Asn Cys Ser Asn Ser Ile 
    210                 215                 220                 


Tyr 
225 


<210>  2287
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  2287

Lys Glu Val Cys Tyr Gly Gln Leu Gly Cys Phe Ser Asp Glu Lys Pro 
1               5                   10                  15      


Trp Ala Gly Thr Leu Gln Arg Pro Val Lys Leu Leu Pro Trp Ser Pro 
            20                  25                  30          


Glu Asp Ile Asp Thr Arg Phe Leu Leu Tyr Thr Asn Glu Asn Pro Asn 
        35                  40                  45              


Asn Phe Gln Leu Ile Thr Gly Thr Glu Pro Asp Thr Ile Glu Ala Ser 
    50                  55                  60                  


Asn Phe Gln Leu Asp Arg Lys Thr Arg Phe Ile Ile His Gly Phe Leu 
65                  70                  75                  80  


Asp Lys Ala Glu Asp Ser Trp Pro Ser Asp Met Cys Lys Lys Met Phe 
                85                  90                  95      


Glu Val Glu Lys Val Asn Cys Ile Cys Val Asp Trp Arg His Gly Ser 
            100                 105                 110         


Arg Ala Met Tyr Thr Gln Ala Val Gln Asn Ile Arg Val Val Gly Ala 
        115                 120                 125             


Glu Thr Ala Phe Leu Ile Gln Ala Leu Ser Thr Gln Leu Gly Tyr Ser 
    130                 135                 140                 


Leu Glu Asp Val His Val Ile Gly His Ser Leu Gly Ala His Thr Ala 
145                 150                 155                 160 


Ala Glu Ala Gly Arg Arg Leu Gly Gly Arg Val Gly Arg Ile Thr Gly 
                165                 170                 175     


Leu Asp Pro Ala Gly Pro Cys Phe Gln Asp Glu Pro Glu Glu Val Arg 
            180                 185                 190         


Leu Asp Pro Ser Asp Ala Val Phe Val Asp Val Ile His Thr Asp Ser 
        195                 200                 205             


Ser Pro Ile Val Pro Ser Leu Gly Phe Gly Met Ser Gln Lys Val Gly 
    210                 215                 220                 


His Leu Asp Phe Phe Pro Asn Gly Gly Lys Glu Met Pro Gly Cys Lys 
225                 230                 235                 240 


Lys Asn Val Leu Ser Thr Ile Thr Asp Ile Asp Gly Ile Trp Glu Gly 
                245                 250                 255     


Ile Gly Gly Phe Val Ser Cys Asn His Leu Arg Ser Phe Glu Tyr Tyr 
            260                 265                 270         


Ser Ser Ser Val Leu Asn Pro Asp Gly Phe Leu Gly Tyr Pro Cys Ala 
        275                 280                 285             


Ser Tyr Asp Glu Phe Gln Glu Ser Lys Cys Phe Pro Cys Pro Ala Glu 
    290                 295                 300                 


Gly Cys Pro Lys Met Gly His Tyr Ala Asp Gln Phe Lys Gly Lys Thr 
305                 310                 315                 320 


Ser Ala Val Glu Gln Thr Phe Phe Leu Asn Thr Gly Glu Ser Gly Asn 
                325                 330                 335     


Phe Thr Ser Trp Arg Tyr Lys Val Ser Val Thr Leu Ser Gly Lys Glu 
            340                 345                 350         


Lys Val Asn Gly Tyr Ile Arg Ile Ala Leu Tyr Gly Ser Asn Glu Asn 
        355                 360                 365             


Ser Lys Gln Tyr Glu Ile Phe Lys Gly Ser Leu Lys Pro Asp Ala Ser 
    370                 375                 380                 


His Thr Cys Ala Ile Asp Val Asp Phe Asn Val Gly Lys Ile Gln Lys 
385                 390                 395                 400 


Val Lys Phe Leu Trp Asn Lys Arg Gly Ile Asn Leu Ser Glu Pro Lys 
                405                 410                 415     


Leu Gly Ala Ser Gln Ile Thr Val Gln Ser Gly Glu Asp Gly Thr Glu 
            420                 425                 430         


Tyr Asn Phe Cys Ser Ser Asp Thr Val Glu Glu Asn Val Leu Gln Ser 
        435                 440                 445             


Leu Tyr Pro Cys 
    450         


<210>  2288
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2288

Thr Met Trp Val Met Leu Gln Thr Leu Asn Asp Glu Val Pro Lys Tyr 
1               5                   10                  15      


Arg Asp Gln Ile Pro Ser Pro Gly Leu Met Val Phe Pro Lys Pro Val 
            20                  25                  30          


Thr Ala Leu Glu Tyr Thr Phe Ser Arg Ser Asp Pro Thr Ser Tyr Ala 
        35                  40                  45              


Gly Tyr Ile Glu Asp Leu Lys Lys Phe Leu Lys Pro Tyr Thr Leu Glu 
    50                  55                  60                  


Glu Gln Lys Asn Leu Thr Val Cys Pro Asp Gly Ala Leu Phe Glu Gln 
65                  70                  75                  80  


Lys Gly Pro Val Tyr Val Ala Cys Gln Phe Pro Ile Ser Leu Leu Gln 
                85                  90                  95      


Ala Cys Ser Gly Met Asn Asp Pro Asp Phe Gly Tyr Ser Gln Gly Asn 
            100                 105                 110         


Pro Cys Ile Leu Val Lys Met Asn Arg Ile Ile Gly Leu Lys Pro Glu 
        115                 120                 125             


Gly Val Pro Arg Ile Asp Cys Val Ser Lys Asn Glu Asp Ile Pro Asn 
    130                 135                 140                 


Val Ala Val Tyr Pro His Asn Gly Met Ile Asp Leu Lys Tyr Phe Pro 
145                 150                 155                 160 


Tyr Tyr Gly Lys Lys Leu His Val Gly Tyr Leu Gln Pro Leu Val Ala 
                165                 170                 175     


Val Gln Val Ser Phe Ala Pro Asn Asn Thr Gly Lys Glu Val Thr Val 
            180                 185                 190         


Glu Cys Lys Ile Asp Gly Ser Ala Asn Leu Lys Ser Gln Asp Asp Arg 
        195                 200                 205             


Asp Lys Phe Leu Gly Arg Val Met Phe Lys Ile Thr Ala Arg Ala 
    210                 215                 220             


<210>  2289
<211>  568
<212>  PRT
<213>  Homo Sapiens

<400>  2289

His Arg Val His Asp Asp Lys Pro Asn Ile Val Leu Ile Met Val Asp 
1               5                   10                  15      


Asp Leu Gly Ile Gly Asp Leu Gly Cys Tyr Gly Asn Asp Thr Met Arg 
            20                  25                  30          


Thr Pro His Ile Asp Arg Leu Ala Arg Glu Gly Val Arg Leu Thr Gln 
        35                  40                  45              


His Ile Ser Ala Ala Ser Leu Cys Ser Pro Ser Arg Ser Ala Phe Leu 
    50                  55                  60                  


Thr Gly Arg Tyr Pro Ile Arg Ser Gly Met Val Ser Ser Gly Asn Arg 
65                  70                  75                  80  


Arg Val Ile Gln Asn Leu Ala Val Pro Ala Gly Leu Pro Leu Asn Glu 
                85                  90                  95      


Thr Thr Leu Ala Ala Leu Leu Lys Lys Gln Gly Tyr Ser Thr Gly Leu 
            100                 105                 110         


Ile Gly Lys Trp His Gln Gly Leu Asn Cys Asp Ser Arg Ser Asp Gln 
        115                 120                 125             


Cys His His Pro Tyr Asn Tyr Gly Phe Asp Tyr Tyr Tyr Gly Met Pro 
    130                 135                 140                 


Phe Thr Leu Val Asp Ser Cys Trp Pro Asp Pro Ser Arg Asn Thr Glu 
145                 150                 155                 160 


Leu Ala Phe Glu Ser Gln Leu Trp Leu Cys Val Gln Leu Val Ala Ile 
                165                 170                 175     


Ala Ile Leu Thr Leu Thr Phe Gly Lys Leu Ser Gly Trp Val Ser Val 
            180                 185                 190         


Pro Trp Leu Leu Ile Phe Ser Met Ile Leu Phe Ile Phe Leu Leu Gly 
        195                 200                 205             


Tyr Ala Trp Phe Ser Ser His Thr Ser Pro Leu Tyr Trp Asp Cys Leu 
    210                 215                 220                 


Leu Met Arg Gly His Glu Ile Thr Glu Gln Pro Met Lys Ala Glu Arg 
225                 230                 235                 240 


Ala Gly Ser Ile Met Val Lys Glu Ala Ile Ser Phe Leu Glu Arg His 
                245                 250                 255     


Ser Lys Glu Thr Phe Leu Leu Phe Phe Ser Phe Leu His Val His Thr 
            260                 265                 270         


Pro Leu Pro Thr Thr Asp Asp Phe Thr Gly Thr Ser Lys His Gly Leu 
        275                 280                 285             


Tyr Gly Asp Asn Val Glu Glu Met Asp Ser Met Val Gly Lys Ile Leu 
    290                 295                 300                 


Asp Ala Ile Asp Asp Phe Gly Leu Arg Asn Asn Thr Leu Val Tyr Phe 
305                 310                 315                 320 


Thr Ser Asp His Gly Gly His Leu Glu Ala Arg Arg Gly His Ala Gln 
                325                 330                 335     


Leu Gly Gly Trp Asn Gly Ile Tyr Lys Gly Gly Lys Gly Met Gly Gly 
            340                 345                 350         


Trp Glu Gly Gly Ile Arg Val Pro Gly Ile Val Arg Trp Pro Gly Lys 
        355                 360                 365             


Val Pro Ala Gly Arg Leu Ile Lys Glu Pro Thr Ser Leu Met Asp Ile 
    370                 375                 380                 


Leu Pro Thr Val Ala Ser Val Ser Gly Gly Ser Leu Pro Gln Asp Arg 
385                 390                 395                 400 


Val Ile Asp Gly Arg Asp Leu Met Pro Leu Leu Gln Gly Asn Val Arg 
                405                 410                 415     


His Ser Glu His Glu Phe Leu Phe His Tyr Cys Gly Ser Tyr Leu His 
            420                 425                 430         


Ala Val Arg Trp Ile Pro Lys Asp Asp Ser Gly Ser Val Trp Lys Ala 
        435                 440                 445             


His Tyr Val Thr Pro Val Phe Gln Pro Pro Ala Ser Gly Gly Cys Tyr 
    450                 455                 460                 


Val Thr Ser Leu Cys Arg Cys Phe Gly Glu Gln Val Thr Tyr His Asn 
465                 470                 475                 480 


Pro Pro Leu Leu Phe Asp Leu Ser Arg Asp Pro Ser Glu Ser Thr Pro 
                485                 490                 495     


Leu Thr Pro Ala Thr Glu Pro Leu Tyr Asp Phe Val Ile Lys Lys Val 
            500                 505                 510         


Ala Asn Ala Leu Lys Glu His Gln Glu Thr Ile Val Pro Val Thr Tyr 
        515                 520                 525             


Gln Leu Ser Glu Leu Asn Gln Gly Arg Thr Trp Leu Lys Pro Cys Cys 
    530                 535                 540                 


Gly Val Phe Pro Phe Cys Leu Cys Asp Lys Glu Glu Glu Val Ser Gln 
545                 550                 555                 560 


Pro Arg Gly Pro Asn Glu Lys Arg 
                565             


<210>  2290
<211>  643
<212>  PRT
<213>  Homo Sapiens

<400>  2290

Tyr Val Leu Asp Asp Ser Asp Gly Leu Gly Arg Glu Phe Asp Gly Ile 
1               5                   10                  15      


Gly Ala Val Ser Gly Gly Gly Ala Thr Ser Arg Leu Leu Val Asn Tyr 
            20                  25                  30          


Pro Glu Pro Tyr Arg Ser Gln Ile Leu Asp Tyr Leu Phe Lys Pro Asn 
        35                  40                  45              


Phe Gly Ala Ser Leu His Ile Leu Lys Val Glu Ile Gly Gly Asp Gly 
    50                  55                  60                  


Gln Thr Thr Asp Gly Thr Glu Pro Ser His Met His Tyr Ala Leu Asp 
65                  70                  75                  80  


Glu Asn Tyr Phe Arg Gly Tyr Glu Trp Trp Leu Met Lys Glu Ala Lys 
                85                  90                  95      


Lys Arg Asn Pro Asn Ile Thr Leu Ile Gly Leu Pro Trp Ser Phe Pro 
            100                 105                 110         


Gly Trp Leu Gly Lys Gly Phe Asp Trp Pro Tyr Val Asn Leu Gln Leu 
        115                 120                 125             


Thr Ala Tyr Tyr Val Val Thr Trp Ile Val Gly Ala Lys Arg Tyr His 
    130                 135                 140                 


Asp Leu Asp Ile Asp Tyr Ile Gly Ile Trp Asn Glu Arg Ser Tyr Asn 
145                 150                 155                 160 


Ala Asn Tyr Ile Lys Ile Leu Arg Lys Met Leu Asn Tyr Gln Gly Leu 
                165                 170                 175     


Gln Arg Val Lys Ile Ile Ala Ser Asp Asn Leu Trp Glu Ser Ile Ser 
            180                 185                 190         


Ala Ser Met Leu Leu Asp Ala Glu Leu Phe Lys Val Val Asp Val Ile 
        195                 200                 205             


Gly Ala His Tyr Pro Gly Thr His Ser Ala Lys Asp Ala Lys Leu Thr 
    210                 215                 220                 


Gly Lys Lys Leu Trp Ser Ser Glu Asp Phe Ser Thr Leu Asn Ser Asp 
225                 230                 235                 240 


Met Gly Ala Gly Cys Trp Gly Arg Ile Leu Asn Gln Asn Tyr Ile Asn 
                245                 250                 255     


Gly Tyr Met Thr Ser Thr Ile Ala Trp Asn Leu Val Ala Ser Tyr Tyr 
            260                 265                 270         


Glu Gln Leu Pro Tyr Gly Arg Cys Gly Leu Met Thr Ala Gln Glu Pro 
        275                 280                 285             


Trp Ser Gly His Tyr Val Val Glu Ser Pro Val Trp Val Ser Ala His 
    290                 295                 300                 


Thr Thr Gln Phe Thr Gln Pro Gly Trp Tyr Tyr Leu Lys Thr Val Gly 
305                 310                 315                 320 


His Leu Glu Lys Gly Gly Ser Tyr Val Ala Leu Thr Asp Gly Leu Gly 
                325                 330                 335     


Asn Leu Thr Ile Ile Ile Glu Thr Met Ser His Lys His Ser Lys Cys 
            340                 345                 350         


Ile Arg Pro Phe Leu Pro Tyr Phe Asn Val Ser Gln Gln Phe Ala Thr 
        355                 360                 365             


Phe Val Leu Lys Gly Ser Phe Ser Glu Ile Pro Glu Leu Gln Val Trp 
    370                 375                 380                 


Tyr Thr Lys Leu Gly Lys Thr Ser Glu Arg Phe Leu Phe Lys Gln Leu 
385                 390                 395                 400 


Asp Ser Leu Trp Leu Leu Asp Ser Asp Gly Ser Phe Thr Leu Ser Leu 
                405                 410                 415     


His Glu Asp Glu Leu Phe Thr Leu Thr Thr Leu Thr Thr Gly Arg Lys 
            420                 425                 430         


Gly Ser Tyr Pro Leu Pro Pro Lys Ser Gln Pro Phe Pro Ser Thr Tyr 
        435                 440                 445             


Lys Asp Asp Phe Asn Val Asp Tyr Pro Phe Phe Ser Glu Ala Pro Asn 
    450                 455                 460                 


Phe Ala Asp Gln Thr Gly Val Phe Glu Tyr Phe Thr Asn Ile Glu Asp 
465                 470                 475                 480 


Pro Gly Glu His His Phe Thr Leu Arg Gln Val Leu Asn Gln Arg Pro 
                485                 490                 495     


Ile Thr Trp Ala Ala Asp Ala Ser Asn Thr Ile Ser Ile Ile Gly Asp 
            500                 505                 510         


Tyr Asn Trp Thr Asn Leu Thr Thr Lys Cys Asp Val Tyr Ile Glu Thr 
        515                 520                 525             


Pro Asp Thr Gly Gly Val Phe Ile Ala Gly Arg Val Asn Lys Gly Gly 
    530                 535                 540                 


Ile Leu Ile Arg Ser Ala Arg Gly Ile Phe Phe Trp Ile Phe Ala Asn 
545                 550                 555                 560 


Gly Ser Tyr Arg Val Thr Gly Asp Leu Ala Gly Trp Ile Ile Tyr Ala 
                565                 570                 575     


Leu Gly Arg Val Glu Val Thr Ala Lys Lys Trp Tyr Thr Leu Thr Leu 
            580                 585                 590         


Thr Ile Lys Gly His Phe Ala Ser Gly Met Leu Asn Asp Lys Ser Leu 
        595                 600                 605             


Trp Thr Asp Ile Pro Val Asn Phe Pro Lys Asn Gly Trp Ala Ala Ile 
    610                 615                 620                 


Gly Thr His Ser Phe Glu Phe Ala Gln Phe Asp Asn Phe Leu Val Glu 
625                 630                 635                 640 


Ala Thr Arg 
            


<210>  2291
<211>  471
<212>  PRT
<213>  Homo Sapiens

<400>  2291

Gly Lys Val Leu Val Trp Pro Thr Glu Tyr Ser His Trp Ile Asn Met 
1               5                   10                  15      


Lys Thr Ile Leu Glu Glu Leu Val Gln Arg Gly His Glu Val Ile Val 
            20                  25                  30          


Leu Thr Ser Ser Ala Ser Ile Leu Val Asn Ala Ser Lys Ser Ser Ala 
        35                  40                  45              


Ile Lys Leu Glu Val Tyr Pro Thr Ser Leu Thr Lys Asn Asp Leu Glu 
    50                  55                  60                  


Asp Phe Phe Met Lys Met Phe Asp Arg Trp Thr Tyr Ser Ile Ser Lys 
65                  70                  75                  80  


Asn Thr Phe Trp Ser Tyr Phe Ser Gln Leu Gln Glu Leu Cys Trp Glu 
                85                  90                  95      


Tyr Ser Asp Tyr Asn Ile Lys Leu Cys Glu Asp Ala Val Leu Asn Lys 
            100                 105                 110         


Lys Leu Met Arg Lys Leu Gln Glu Ser Lys Phe Asp Val Leu Leu Ala 
        115                 120                 125             


Asp Ala Val Asn Pro Cys Gly Glu Leu Leu Ala Glu Leu Leu Asn Ile 
    130                 135                 140                 


Pro Phe Leu Tyr Ser Leu Arg Phe Ser Val Gly Tyr Thr Val Glu Lys 
145                 150                 155                 160 


Asn Gly Gly Gly Phe Leu Phe Pro Pro Ser Tyr Val Pro Val Val Met 
                165                 170                 175     


Ser Glu Leu Ser Asp Gln Met Ile Phe Met Glu Arg Ile Lys Asn Met 
            180                 185                 190         


Ile Tyr Met Leu Tyr Phe Asp Phe Trp Phe Gln Ala Tyr Asp Leu Lys 
        195                 200                 205             


Lys Trp Asp Gln Phe Tyr Ser Glu Val Leu Gly Arg Pro Thr Thr Leu 
    210                 215                 220                 


Phe Glu Thr Met Gly Lys Ala Glu Met Trp Leu Ile Arg Thr Tyr Trp 
225                 230                 235                 240 


Asp Phe Glu Phe Pro Arg Pro Phe Leu Pro Asn Val Asp Phe Val Gly 
                245                 250                 255     


Gly Leu His Cys Lys Pro Ala Lys Pro Leu Pro Lys Glu Met Glu Glu 
            260                 265                 270         


Phe Val Gln Ser Ser Gly Glu Asn Gly Ile Val Val Phe Ser Leu Gly 
        275                 280                 285             


Ser Met Ile Ser Asn Met Ser Glu Glu Ser Ala Asn Met Ile Ala Ser 
    290                 295                 300                 


Ala Leu Ala Gln Ile Pro Gln Lys Val Leu Trp Arg Phe Asp Gly Lys 
305                 310                 315                 320 


Lys Pro Asn Thr Leu Gly Ser Asn Thr Arg Leu Tyr Lys Trp Leu Pro 
                325                 330                 335     


Gln Asn Asp Leu Leu Gly His Pro Lys Thr Lys Ala Phe Ile Thr His 
            340                 345                 350         


Gly Gly Thr Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Ile Pro Met 
        355                 360                 365             


Val Gly Ile Pro Leu Phe Ala Asp Gln His Asp Asn Ile Ala His Met 
    370                 375                 380                 


Lys Ala Lys Gly Ala Ala Leu Ser Val Asp Ile Arg Thr Met Ser Ser 
385                 390                 395                 400 


Arg Asp Leu Leu Asn Ala Leu Lys Ser Val Ile Asn Asp Pro Ile Tyr 
                405                 410                 415     


Lys Glu Asn Ile Met Lys Leu Ser Arg Ile His His Asp Gln Pro Val 
            420                 425                 430         


Lys Pro Leu Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His 
        435                 440                 445             


Lys Gly Ala Lys His Leu Arg Val Ala Ala His Asn Leu Thr Trp Ile 
    450                 455                 460                 


Gln Tyr His Ser Leu Asp Val 
465                 470     


<210>  2292
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  2292

Gln Gly Gln Tyr Asp Leu Asp Pro Leu Pro Pro Phe Pro Asp His Val 
1               5                   10                  15      


Gln Tyr Thr His Tyr Ser Asp Gln Ile Asp Asn Pro Asp Tyr Tyr Asp 
            20                  25                  30          


Tyr Gln Glu Val Thr Pro Arg Pro Ser Glu Glu Gln Phe Gln Phe Gln 
        35                  40                  45              


Ser Gln Gln Gln Val Gln Gln Glu Val Ile Pro Ala Pro Thr Pro Glu 
    50                  55                  60                  


Pro Gly Asn Ala Glu Leu Glu Pro Thr Glu Pro Gly Pro Leu Asp Cys 
65                  70                  75                  80  


Arg Glu Glu Gln Tyr Pro Cys Thr Arg Leu Tyr Ser Ile His Arg Pro 
                85                  90                  95      


Cys Lys Gln Cys Leu Asn Glu Val Cys Phe Tyr Ser Leu Arg Arg Val 
            100                 105                 110         


Tyr Val Ile Asn Lys Glu Ile Cys Val Arg Thr Val Cys Ala His Glu 
        115                 120                 125             


Glu Leu Leu Arg Ala Asp Leu Cys Arg Asp Lys Phe Ser Lys Cys Gly 
    130                 135                 140                 


Val Met Ala Ser Ser Gly Leu Cys Gln Ser Val Ala Ala Ser Cys Ala 
145                 150                 155                 160 


Arg Ser Cys Gly Ser Cys 
                165     


<210>  2293
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  2293

Glu Ala Gln Glu Gly Thr Leu Ser Pro Pro Pro Lys Leu Lys Met Ser 
1               5                   10                  15      


Arg Trp Ser Leu Val Arg Gly Arg Met Lys Glu Leu Leu Glu Thr Val 
            20                  25                  30          


Val Asn Arg Thr Arg Asp Gly Trp Gln Trp Phe Trp Ser Pro Ser Thr 
        35                  40                  45              


Phe Arg Gly Phe Met Gln Thr Tyr Tyr Asp Asp His Leu Arg Asp Leu 
    50                  55                  60                  


Gly Pro Leu Thr Lys Ala Trp Phe Leu Glu Ser Lys Asp Ser Leu Leu 
65                  70                  75                  80  


Lys Lys Thr His Ser Leu Cys Pro Arg Leu Val Cys Gly Asp Lys Asp 
                85                  90                  95      


Gln Gly 
        


<210>  2294
<211>  476
<212>  PRT
<213>  Homo Sapiens

<400>  2294

Glu Phe Pro Gly Cys Lys Ile Arg Val Thr Ser Lys Ala Leu Glu Leu 
1               5                   10                  15      


Val Lys Gln Glu Gly Leu Arg Phe Leu Glu Gln Glu Leu Glu Thr Ile 
            20                  25                  30          


Thr Ile Pro Asp Leu Arg Gly Lys Glu Gly His Phe Tyr Tyr Asn Ile 
        35                  40                  45              


Ser Glu Val Lys Val Thr Glu Leu Gln Leu Thr Ser Ser Glu Leu Asp 
    50                  55                  60                  


Phe Gln Pro Gln Gln Glu Leu Met Leu Gln Ile Thr Asn Ala Ser Leu 
65                  70                  75                  80  


Gly Leu Arg Phe Arg Arg Gln Leu Leu Tyr Trp Phe Phe Tyr Asp Gly 
                85                  90                  95      


Gly Tyr Ile Asn Ala Ser Ala Glu Gly Val Ser Ile Arg Thr Gly Leu 
            100                 105                 110         


Glu Leu Ser Arg Asp Pro Ala Gly Arg Met Lys Val Ser Asn Val Ser 
        115                 120                 125             


Cys Gln Ala Ser Val Ser Arg Met His Ala Ala Phe Gly Gly Thr Phe 
    130                 135                 140                 


Lys Lys Val Tyr Asp Phe Leu Ser Thr Phe Ile Thr Ser Gly Met Arg 
145                 150                 155                 160 


Phe Leu Leu Asn Gln Gln Ile Cys Pro Val Leu Tyr His Ala Gly Thr 
                165                 170                 175     


Val Leu Leu Asn Ser Leu Leu Asp Thr Val Pro Val Arg Ser Ser Val 
            180                 185                 190         


Asp Glu Leu Val Gly Ile Asp Tyr Ser Leu Met Lys Asp Pro Val Ala 
        195                 200                 205             


Ser Thr Ser Asn Leu Asp Met Asp Phe Arg Gly Ala Phe Phe Pro Leu 
    210                 215                 220                 


Thr Glu Arg Asn Trp Ser Leu Pro Asn Arg Ala Val Glu Pro Gln Leu 
225                 230                 235                 240 


Gln Glu Glu Glu Arg Met Val Tyr Val Ala Phe Ser Glu Phe Phe Phe 
                245                 250                 255     


Asp Ser Ala Met Glu Ser Tyr Phe Arg Ala Gly Ala Leu Gln Leu Leu 
            260                 265                 270         


Leu Val Gly Asp Lys Val Pro His Asp Leu Asp Met Leu Leu Arg Ala 
        275                 280                 285             


Thr Tyr Phe Gly Ser Ile Val Leu Leu Ser Pro Ala Val Ile Asp Ser 
    290                 295                 300                 


Pro Leu Lys Leu Glu Leu Arg Val Leu Ala Pro Pro Arg Cys Thr Ile 
305                 310                 315                 320 


Lys Pro Ser Gly Thr Thr Ile Ser Val Thr Ala Ser Val Thr Ile Ala 
                325                 330                 335     


Leu Val Pro Pro Asp Gln Pro Glu Val Gln Leu Ser Ser Met Thr Met 
            340                 345                 350         


Asp Ala Arg Leu Ser Ala Lys Met Ala Leu Arg Gly Lys Ala Leu Arg 
        355                 360                 365             


Thr Gln Leu Asp Leu Arg Arg Phe Arg Ile Tyr Ser Asn His Ser Ala 
    370                 375                 380                 


Leu Glu Ser Leu Ala Leu Ile Pro Leu Gln Ala Pro Leu Lys Thr Met 
385                 390                 395                 400 


Leu Gln Ile Gly Val Met Pro Met Leu Asn Glu Arg Thr Trp Arg Gly 
                405                 410                 415     


Val Gln Ile Pro Leu Pro Glu Gly Ile Asn Phe Val His Glu Val Val 
            420                 425                 430         


Thr Asn His Ala Gly Phe Leu Thr Ile Gly Ala Asp Leu His Phe Ala 
        435                 440                 445             


Lys Gly Leu Arg Glu Val Ile Glu Lys Asn Arg Pro Ala Asp Val Arg 
    450                 455                 460                 


Ala Ser Thr Ala Pro Thr Pro Ser Thr Ala Ala Val 
465                 470                 475     


<210>  2295
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2295

Val Ser Gly Ile Arg Gly Asp Ala Leu Glu Arg Phe Cys Leu Gln Gln 
1               5                   10                  15      


Pro Leu Asp Cys Asp Asp Ile Tyr Ala Gln Gly Tyr Gln Ser Asp Gly 
            20                  25                  30          


Val Tyr Leu Ile Tyr Pro Ser Gly Pro Ser Val Pro Val Pro Val Phe 
        35                  40                  45              


Cys Asp Met Thr Thr Glu Gly Gly Lys Trp Thr Val Phe Gln Lys Arg 
    50                  55                  60                  


Phe Asn Gly Ser Val Ser Phe Phe Arg Gly Trp Asn Asp Tyr Lys Leu 
65                  70                  75                  80  


Gly Phe Gly Arg Ala Asp Gly Glu Tyr Trp Leu Gly Leu Gln Asn Met 
                85                  90                  95      


His Leu Leu Thr Leu Lys Gln Lys Tyr Glu Leu Arg Val Asp Leu Glu 
            100                 105                 110         


Asp Phe Glu Asn Asn Thr Ala Tyr Ala Lys Tyr Ala Asp Phe Ser Ile 
        115                 120                 125             


Ser Pro Asn Ala Val Ser Ala Glu Glu Asp Gly Tyr Thr Leu Phe Val 
    130                 135                 140                 


Ala Gly Phe Glu Asp Gly Gly Val Gly Asp Ser Leu Ser Tyr His Ser 
145                 150                 155                 160 


Gly Gln Lys Phe Ser Thr Phe Asp Arg Asp Gln Asp Leu Phe Val Gln 
                165                 170                 175     


Asn Cys Ala Ala Leu Ser Ser Gly Ala Phe Trp Phe Arg Ser Cys His 
            180                 185                 190         


Phe Ala Asn Leu Asn Gly Phe Tyr Leu Gly Gly Ser His Leu Ser Tyr 
        195                 200                 205             


Ala Asn Gly Ile Asn Trp Ala Gln Trp Lys Gly Phe Tyr Tyr Ser Leu 
    210                 215                 220                 


Lys Arg Thr Glu Met Lys Ile Arg Arg Ala 
225                 230                 


<210>  2296
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  2296

Gly Ile Asp Cys Gln Gly Gly Ser Arg Met Cys Cys Arg Gln Glu Phe 
1               5                   10                  15      


Phe Val Asp Phe Arg Glu Ile Gly Trp His Asp Trp Ile Ile Gln Pro 
            20                  25                  30          


Glu Gly Tyr Ala Met Asn Phe Cys Ile Gly Gln Cys Pro Leu His Ile 
        35                  40                  45              


Ala Gly Met Pro Gly Ile Ala Ala Ser Phe His Thr Ala Val Leu Asn 
    50                  55                  60                  


Leu Leu Lys Ala Asn Thr Ala Ala Gly Thr Thr Gly Gly Gly Ser Cys 
65                  70                  75                  80  


Cys Val Pro Thr Ala Arg Arg Pro Leu Ser Leu Leu Tyr Tyr Asp Arg 
                85                  90                  95      


Asp Ser Asn Ile Val Lys Thr Asp Ile Pro Asp Met Val Val Glu Ala 
            100                 105                 110         


Cys Gly Cys Ser 
        115     


<210>  2297
<211>  158
<212>  PRT
<213>  Homo Sapiens

<400>  2297

Leu Arg Pro Gly Asp Cys Glu Val Cys Ile Ser Tyr Leu Gly Arg Phe 
1               5                   10                  15      


Tyr Gln Asp Leu Lys Asp Arg Asp Val Thr Phe Ser Pro Ala Thr Ile 
            20                  25                  30          


Glu Asn Glu Leu Ile Lys Phe Cys Arg Glu Ala Arg Gly Lys Glu Asn 
        35                  40                  45              


Arg Leu Cys Tyr Tyr Ile Gly Ala Thr Asp Asp Ala Ala Thr Lys Ile 
    50                  55                  60                  


Ile Asn Glu Val Ser Lys Pro Leu Ala His His Ile Pro Val Glu Lys 
65                  70                  75                  80  


Ile Cys Glu Lys Leu Lys Lys Lys Asp Ser Gln Ile Cys Glu Leu Lys 
                85                  90                  95      


Tyr Asp Lys Gln Ile Asp Leu Ser Thr Val Asp Leu Lys Lys Leu Arg 
            100                 105                 110         


Val Lys Glu Leu Lys Lys Ile Leu Asp Asp Trp Gly Glu Thr Cys Lys 
        115                 120                 125             


Gly Cys Ala Glu Lys Ser Asp Tyr Ile Arg Lys Ile Asn Glu Leu Met 
    130                 135                 140                 


Pro Lys Tyr Ala Pro Lys Ala Ala Ser Ala Arg Thr Asp Leu 
145                 150                 155             


<210>  2298
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  2298

Gln Arg Asp Phe Asp Leu Ala Asp Ala Leu Asp Asp Pro Glu Pro Thr 
1               5                   10                  15      


Lys Lys Pro Asn Ser Asp Ile Tyr Pro Lys Pro Lys Pro Pro Tyr Tyr 
            20                  25                  30          


Pro Gln Pro Glu Asn Pro Asp Ser Gly Gly Asn Ile Tyr Pro Arg Pro 
        35                  40                  45              


Lys Pro Arg Pro Gln Pro Gln Pro Gly Asn Ser Gly Asn Ser Gly Gly 
    50                  55                  60                  


Tyr Phe Asn Asp Val Asp Arg Asp Asp Gly Arg Tyr Pro Pro Arg Pro 
65                  70                  75                  80  


Arg Pro Arg Pro Pro Ala Gly Gly Gly Gly Gly Gly Tyr Ser Ser Tyr 
                85                  90                  95      


Gly Asn Ser Asp Asn Thr His Gly Arg Gly Gly Tyr Arg Pro Asn Ser 
            100                 105                 110         


Arg Tyr Gly Asn Thr Tyr Gly Gly Asp His His Ser Thr Tyr Gly Asn 
        115                 120                 125             


Pro Glu Gly Asn Met Val Ala Lys 
    130                 135     


<210>  2299
<211>  279
<212>  PRT
<213>  Homo Sapiens

<400>  2299

Leu His Glu Lys Ala Tyr Gln Val Arg Asp Thr Ala Ile Glu Ser Ser 
1               5                   10                  15      


Val Val Thr Lys Val Lys Gly Ser Gly Leu Tyr Ala Asn Arg Val Met 
            20                  25                  30          


Asp Val Ser Asp Tyr Val Thr Pro Pro Gln Gly Thr Ser Val Phe Val 
        35                  40                  45              


Ile Ile Thr Lys Met Ile Val Thr Glu Asn Gln Met Gln Gly Phe Cys 
    50                  55                  60                  


Pro Glu Ser Glu Glu Lys Tyr Arg Cys Val Ser Asp Ser Gln Cys Gly 
65                  70                  75                  80  


Pro Glu Arg Leu Pro Gly Gly Gly Ile Leu Thr Gly Arg Cys Val Asn 
                85                  90                  95      


Tyr Ser Ser Val Leu Arg Thr Cys Glu Ile Gln Gly Trp Cys Pro Thr 
            100                 105                 110         


Glu Val Asp Thr Val Glu Thr Pro Ile Met Met Glu Ala Glu Asn Phe 
        115                 120                 125             


Thr Ile Phe Ile Lys Asn Ser Ile Arg Phe Pro Leu Phe Asn Phe Glu 
    130                 135                 140                 


Lys Gly Asn Leu Leu Pro Asn Leu Thr Ala Arg Asp Met Lys Thr Cys 
145                 150                 155                 160 


Arg Phe His Pro Asp Lys Asp Pro Phe Cys Pro Ile Leu Arg Val Gly 
                165                 170                 175     


Asp Val Val Lys Phe Ala Gly Gln Asp Phe Ala Lys Leu Ala Arg Thr 
            180                 185                 190         


Gly Gly Val Leu Gly Ile Lys Ile Gly Trp Val Cys Asp Leu Asp Lys 
        195                 200                 205             


Ala Trp Asp Gln Cys Ile Pro Lys Tyr Ser Phe Thr Arg Leu Asp Ser 
    210                 215                 220                 


Val Ser Glu Lys Ser Ser Val Ser Pro Gly Tyr Asn Phe Arg Phe Ala 
225                 230                 235                 240 


Lys Tyr Tyr Lys Met Glu Asn Gly Ser Glu Tyr Arg Thr Leu Leu Lys 
                245                 250                 255     


Ala Phe Gly Ile Arg Phe Asp Val Leu Val Tyr Gly Asn Ala Gly Lys 
            260                 265                 270         


Phe Asn Ile Ile Pro Thr Ile 
        275                 


<210>  2300
<211>  334
<212>  PRT
<213>  Homo Sapiens

<400>  2300

Ser Tyr Pro Ile Trp Trp Ser Leu Ala Val Gly Pro Gln Tyr Ser Ser 
1               5                   10                  15      


Leu Gly Ser Gln Pro Ile Leu Cys Ala Ser Ile Pro Gly Leu Val Pro 
            20                  25                  30          


Lys Gln Leu Arg Phe Cys Arg Asn Tyr Val Glu Ile Met Pro Ser Val 
        35                  40                  45              


Ala Glu Gly Ile Lys Ile Gly Ile Gln Glu Cys Gln His Gln Phe Arg 
    50                  55                  60                  


Gly Arg Arg Trp Asn Cys Thr Thr Val His Asp Ser Leu Ala Ile Phe 
65                  70                  75                  80  


Gly Pro Val Leu Asp Lys Ala Thr Arg Glu Ser Ala Phe Val His Ala 
                85                  90                  95      


Ile Ala Ser Ala Gly Val Ala Phe Ala Val Thr Arg Ser Cys Ala Glu 
            100                 105                 110         


Gly Thr Ala Ala Ile Cys Gly Cys Ser Ser Arg His Gln Gly Ser Pro 
        115                 120                 125             


Gly Lys Gly Trp Lys Trp Gly Gly Cys Ser Glu Asp Ile Glu Phe Gly 
    130                 135                 140                 


Gly Met Val Ser Arg Glu Phe Ala Asp Ala Arg Glu Asn Arg Pro Asp 
145                 150                 155                 160 


Ala Arg Ser Ala Met Asn Arg His Asn Asn Glu Ala Gly Arg Gln Ala 
                165                 170                 175     


Ile Ala Ser His Met His Leu Lys Cys Lys Cys His Gly Leu Ser Gly 
            180                 185                 190         


Ser Cys Glu Val Lys Thr Cys Trp Trp Ser Gln Pro Asp Phe Arg Ala 
        195                 200                 205             


Ile Gly Asp Phe Leu Lys Asp Lys Tyr Asp Ser Ala Ser Glu Met Val 
    210                 215                 220                 


Val Glu Lys His Arg Glu Ser Arg Gly Trp Val Glu Thr Leu Arg Pro 
225                 230                 235                 240 


Arg Tyr Thr Tyr Phe Lys Val Pro Thr Glu Arg Asp Leu Val Tyr Tyr 
                245                 250                 255     


Glu Ala Ser Pro Asn Phe Cys Glu Pro Asn Pro Glu Thr Gly Ser Phe 
            260                 265                 270         


Gly Thr Arg Asp Arg Thr Cys Asn Val Ser Ser His Gly Ile Asp Gly 
        275                 280                 285             


Cys Asp Leu Leu Cys Cys Gly Arg Gly His Asn Ala Arg Ala Glu Arg 
    290                 295                 300                 


Arg Arg Glu Lys Cys Arg Cys Val Phe His Trp Cys Cys Tyr Val Ser 
305                 310                 315                 320 


Cys Gln Glu Cys Thr Arg Val Tyr Asp Val His Thr Cys Lys 
                325                 330                 


<210>  2301
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  2301

Ser Asn Trp Leu Tyr Leu Ala Lys Leu Ser Ser Val Gly Ser Ile Ser 
1               5                   10                  15      


Glu Glu Glu Thr Cys Glu Lys Leu Lys Gly Leu Ile Gln Arg Gln Val 
            20                  25                  30          


Gln Met Cys Lys Arg Asn Leu Glu Val Met Asp Ser Val Arg Arg Gly 
        35                  40                  45              


Ala Gln Leu Ala Ile Glu Glu Cys Gln Tyr Gln Phe Arg Asn Arg Arg 
    50                  55                  60                  


Trp Asn Cys Ser Thr Leu Asp Ser Leu Pro Val Phe Gly Lys Val Val 
65                  70                  75                  80  


Thr Gln Gly Thr Arg Glu Ala Ala Phe Val Tyr Ala Ile Ser Ser Ala 
                85                  90                  95      


Gly Val Ala Phe Ala Val Thr Arg Ala Cys Ser Ser Gly Glu Leu Glu 
            100                 105                 110         


Lys Cys Gly Cys Asp Arg Thr Val His Gly Val Ser Pro Gln Gly Phe 
        115                 120                 125             


Gln Trp Ser Gly Cys Ser Asp Asn Ile Ala Tyr Gly Val Ala Phe Ser 
    130                 135                 140                 


Gln Ser Phe Val Asp Val Arg Glu Arg Ser Lys Gly Ala Ser Ser Ser 
145                 150                 155                 160 


Arg Ala Leu Met Asn Leu His Asn Asn Glu Ala Gly Arg Lys Ala Ile 
                165                 170                 175     


Leu Thr His Met Arg Val Glu Cys Lys Cys His Gly Val Ser Gly Ser 
            180                 185                 190         


Cys Glu Val Lys Thr Cys Trp Arg Ala Val Pro Pro Phe Arg Gln Val 
        195                 200                 205             


Gly His Ala Leu Lys Glu Lys Phe Asp Gly Ala Thr Glu Val Glu Pro 
    210                 215                 220                 


Arg Arg Val Gly Ser Ser Arg Ala Leu Val Pro Arg Asn Ala Gln Phe 
225                 230                 235                 240 


Lys Pro His Thr Asp Glu Asp Leu Val Tyr Leu Glu Pro Ser Pro Asp 
                245                 250                 255     


Phe Cys Glu Gln Asp Met Arg Ser Gly Val Leu Gly Thr Arg Gly Arg 
            260                 265                 270         


Thr Cys Asn Lys Thr Ser Lys Ala Ile Asp Gly Cys Glu Leu Leu Cys 
        275                 280                 285             


Cys Gly Arg Gly Phe His Thr Ala Gln Val Glu Leu Ala Glu Arg Cys 
    290                 295                 300                 


Ser Cys Lys Phe His Trp Cys Cys Phe Val Lys Cys Arg Gln Cys Gln 
305                 310                 315                 320 


Arg Leu Val Glu Leu His Thr Cys Arg 
                325                 


<210>  2302
<211>  325
<212>  PRT
<213>  Homo Sapiens

<400>  2302

Ala Leu Ser Ser Val Val Ala Leu Gly Ala Asn Ile Ile Cys Asn Lys 
1               5                   10                  15      


Ile Pro Gly Leu Ala Pro Arg Gln Arg Ala Ile Cys Gln Ser Arg Pro 
            20                  25                  30          


Asp Ala Ile Ile Val Ile Gly Glu Gly Ala Gln Met Gly Ile Asn Glu 
        35                  40                  45              


Cys Gln Tyr Gln Phe Arg Phe Gly Arg Trp Asn Cys Ser Ala Leu Gly 
    50                  55                  60                  


Glu Lys Thr Val Phe Gly Gln Glu Leu Arg Val Gly Ser Arg Glu Ala 
65                  70                  75                  80  


Ala Phe Thr Tyr Ala Ile Thr Ala Ala Gly Val Ala His Ala Val Thr 
                85                  90                  95      


Ala Ala Cys Ser Gln Gly Asn Leu Ser Asn Cys Gly Cys Asp Arg Glu 
            100                 105                 110         


Lys Gln Gly Tyr Tyr Asn Gln Ala Glu Gly Trp Lys Trp Gly Gly Cys 
        115                 120                 125             


Ser Ala Asp Val Arg Tyr Gly Ile Asp Phe Ser Arg Arg Phe Val Asp 
    130                 135                 140                 


Ala Arg Glu Ile Lys Lys Asn Ala Arg Arg Leu Met Asn Leu His Asn 
145                 150                 155                 160 


Asn Glu Ala Gly Arg Lys Val Leu Glu Asp Arg Met Gln Leu Glu Cys 
                165                 170                 175     


Lys Cys His Gly Val Ser Gly Ser Cys Thr Thr Lys Thr Cys Trp Thr 
            180                 185                 190         


Thr Leu Pro Lys Phe Arg Glu Val Gly His Leu Leu Lys Glu Lys Tyr 
        195                 200                 205             


Asn Ala Ala Val Gln Val Glu Val Val Arg Ala Ser Arg Leu Arg Gln 
    210                 215                 220                 


Pro Thr Phe Leu Arg Ile Lys Gln Leu Arg Ser Tyr Gln Lys Pro Met 
225                 230                 235                 240 


Glu Thr Asp Leu Val Tyr Ile Glu Lys Ser Pro Asn Tyr Cys Glu Glu 
                245                 250                 255     


Asp Ala Ala Thr Gly Ser Val Gly Thr Gln Gly Arg Leu Cys Asn Arg 
            260                 265                 270         


Thr Ser Pro Gly Ala Asp Gly Cys Asp Thr Met Cys Cys Gly Arg Gly 
        275                 280                 285             


Tyr Asn Thr His Gln Tyr Thr Lys Val Trp Gln Cys Asn Cys Lys Phe 
    290                 295                 300                 


His Trp Cys Cys Phe Val Lys Cys Asn Thr Cys Ser Glu Arg Thr Glu 
305                 310                 315                 320 


Val Phe Thr Cys Lys 
                325 


<210>  2303
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2303

Gln Trp Arg Val Ser Ala Phe Ile Glu Asn Asn Ile Val Val Phe Glu 
1               5                   10                  15      


Asn Phe Trp Glu Gly Leu Trp Met Asn Cys Val Arg Gln Ala Asn Ile 
            20                  25                  30          


Arg Met Gln Cys Lys Ile Tyr Asp Ser Leu Leu Ala Leu Ser Pro Asp 
        35                  40                  45              


Leu Gln Ala Ala Arg 
    50              


<210>  2304
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  2304

Asn Trp Arg Lys Leu Arg Leu Ile Thr Phe Asn Arg Asn Glu Lys Asn 
1               5                   10                  15      


Leu Thr Val Tyr Thr Gly Leu Trp Val Lys Cys Ala Arg Tyr Asp Gly 
            20                  25                  30          


Ser Ser Asp Cys Leu Met Tyr Asp Thr Thr Trp Tyr Ser Ser Val Asp 
        35                  40                  45              


Gln Leu Asp Leu Arg Val Leu Gln 
    50                  55      


<210>  2305
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2305

Gln Trp Arg Val Ser Ala Phe Val Gly Ser Asn Ile Ile Val Phe Glu 
1               5                   10                  15      


Arg Leu Trp Glu Gly Leu Trp Met Asn Cys Ile Arg Gln Ala Arg Val 
            20                  25                  30          


Arg Leu Gln Cys Lys Phe Tyr Ser Ser Leu Leu Ala Leu Pro Pro Ala 
        35                  40                  45              


Leu Glu Thr Ala Arg 
    50              


<210>  2306
<211>  436
<212>  PRT
<213>  Homo Sapiens

<400>  2306

Thr Gln His Gly Ile Arg Leu Pro Leu Arg Ser Gly Leu Gly Gly Ala 
1               5                   10                  15      


Pro Leu Gly Leu Arg Leu Pro Arg Glu Thr Asp Glu Glu Pro Glu Glu 
            20                  25                  30          


Pro Gly Arg Arg Gly Ser Phe Val Glu Met Val Asp Asn Leu Arg Gly 
        35                  40                  45              


Lys Ser Gly Gln Gly Tyr Tyr Val Glu Met Thr Val Gly Ser Pro Pro 
    50                  55                  60                  


Gln Thr Leu Asn Ile Leu Val Asp Thr Gly Ser Ser Asn Phe Ala Val 
65                  70                  75                  80  


Gly Ala Ala Pro His Pro Phe Leu His Arg Tyr Tyr Gln Arg Gln Leu 
                85                  90                  95      


Phe Ser Thr Tyr Arg Asp Leu Arg Lys Gly Val Tyr Val Pro Tyr Thr 
            100                 105                 110         


Gln Gly Lys Trp Glu Gly Glu Leu Gly Thr Asp Leu Val Ser Ile Pro 
        115                 120                 125             


His Gly Pro Asn Val Thr Val Arg Ala Asn Ile Ala Ala Ile Thr Glu 
    130                 135                 140                 


Ser Asp Lys Phe Phe Ile Asn Gly Ser Asn Trp Glu Gly Ile Leu Gly 
145                 150                 155                 160 


Leu Ala Tyr Ala Glu Ile Ala Arg Pro Asp Asp Ser Leu Glu Pro Phe 
                165                 170                 175     


Phe Asp Ser Leu Val Lys Gln Thr His Val Pro Asn Leu Phe Ser Leu 
            180                 185                 190         


Gln Leu Cys Gly Ala Gly Phe Pro Leu Asn Gln Ser Glu Val Leu Ala 
        195                 200                 205             


Ser Val Gly Gly Ser Met Ile Ile Gly Gly Ile Asp His Ser Leu Tyr 
    210                 215                 220                 


Thr Gly Ser Leu Trp Tyr Thr Pro Ile Arg Arg Glu Trp Tyr Tyr Glu 
225                 230                 235                 240 


Val Ile Ile Val Arg Val Glu Ile Asn Gly Gln Asp Leu Lys Met Asp 
                245                 250                 255     


Cys Lys Glu Tyr Asn Tyr Asp Lys Ser Ile Val Asp Ser Gly Thr Thr 
            260                 265                 270         


Asn Leu Arg Leu Pro Lys Lys Val Phe Glu Ala Ala Val Lys Ser Ile 
        275                 280                 285             


Lys Ala Ala Ser Ser Thr Glu Lys Phe Pro Asp Gly Phe Trp Leu Gly 
    290                 295                 300                 


Glu Gln Leu Val Cys Trp Gln Ala Gly Thr Thr Pro Trp Asn Ile Phe 
305                 310                 315                 320 


Pro Val Ile Ser Leu Tyr Leu Met Gly Glu Val Thr Asn Gln Ser Phe 
                325                 330                 335     


Arg Ile Thr Ile Leu Pro Gln Gln Tyr Leu Arg Pro Val Glu Asp Val 
            340                 345                 350         


Ala Thr Ser Gln Asp Asp Cys Tyr Lys Phe Ala Ile Ser Gln Ser Ser 
        355                 360                 365             


Thr Gly Thr Val Met Gly Ala Val Ile Met Glu Gly Phe Tyr Val Val 
    370                 375                 380                 


Phe Asp Arg Ala Arg Lys Arg Ile Gly Phe Ala Val Ser Ala Cys His 
385                 390                 395                 400 


Val His Asp Glu Phe Arg Thr Ala Ala Val Glu Gly Pro Phe Val Thr 
                405                 410                 415     


Leu Asp Met Glu Asp Cys Gly Tyr Asn Ile Pro Gln Thr Asp Glu Ser 
            420                 425                 430         


Thr Leu Met Thr 
        435     


<210>  2307
<211>  122
<212>  PRT
<213>  Homo Sapiens

<400>  2307

Lys Glu Val Ser Trp Arg Glu Phe Met Lys Gln His Tyr Leu Ser Pro 
1               5                   10                  15      


Ser Arg Glu Phe Arg Glu Tyr Lys Cys Asp Val Leu Met Arg Glu Asn 
            20                  25                  30          


Glu Ala Leu Lys Asp Lys Ser Ser His Met Phe Ile Tyr Ile Ser Trp 
        35                  40                  45              


Tyr Lys Ile Glu His Ile Cys Thr Ser Asp Asn Trp Met Asp Arg Phe 
    50                  55                  60                  


Arg Asn Ala Tyr Val Trp Val Gln Asn Pro Leu Lys Val Leu Lys Cys 
65                  70                  75                  80  


His Gln Glu Asn Ser Lys Asn Ser Tyr Thr Glu Ser Arg Ser Phe Asn 
                85                  90                  95      


Tyr Ile Glu Phe His Cys Ser Met Asp Gly Tyr Val Asp Ser Ile Glu 
            100                 105                 110         


Asp Leu Lys Met Val Glu Pro Ile Gly Asn 
        115                 120         


<210>  2308
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2308

Asp Met Trp Ser Thr Gln Asp Leu Tyr Asp Asn Pro Val Thr Ser Val 
1               5                   10                  15      


Phe Gln Tyr Glu Gly Leu Trp Arg Ser Cys Val Arg Gln Ser Ser Gly 
            20                  25                  30          


Phe Thr Glu Cys Arg Pro Tyr Phe Thr Ile Leu Gly Leu Pro Ala Met 
        35                  40                  45              


Leu Gln Ala Val Arg 
    50              


<210>  2309
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2309

Asn Trp Lys Val Asn Val Asp Val Asp Ser Asn Ile Ile Thr Ala Ile 
1               5                   10                  15      


Val Gln Leu His Gly Leu Trp Met Asp Cys Thr Trp Tyr Ser Thr Gly 
            20                  25                  30          


Met Phe Ser Cys Ala Leu Lys His Ser Ile Leu Ser Leu Pro Ile His 
        35                  40                  45              


Val Gln Ala Ala Arg 
    50              


<210>  2310
<211>  229
<212>  PRT
<213>  Homo Sapiens

<400>  2310

Met Arg Lys Val Val Leu Ile Thr Gly Ala Ser Ser Gly Ile Gly Leu 
1               5                   10                  15      


Ala Leu Cys Lys Arg Leu Leu Ala Glu Asp Asp Glu Leu His Leu Cys 
            20                  25                  30          


Leu Ala Cys Arg Asn Met Ser Lys Ala Glu Ala Val Cys Ala Ala Leu 
        35                  40                  45              


Leu Ala Ser His Pro Thr Ala Glu Val Thr Ile Val Gln Val Asp Val 
    50                  55                  60                  


Ser Asn Leu Gln Ser Val Phe Arg Ala Ser Lys Glu Leu Lys Gln Arg 
65                  70                  75                  80  


Phe Gln Arg Leu Asp Cys Ile Tyr Leu Asn Ala Gly Ile Met Pro Asn 
                85                  90                  95      


Pro Gln Leu Asn Ile Lys Ala Leu Phe Phe Gly Leu Phe Ser Arg Lys 
            100                 105                 110         


Val Ile His Met Phe Ser Thr Ala Glu Gly Leu Leu Thr Gln Gly Asp 
        115                 120                 125             


Lys Ile Thr Ala Asp Gly Leu Gln Glu Val Phe Glu Thr Asn Val Phe 
    130                 135                 140                 


Gly His Phe Ile Leu Ile Arg Glu Leu Glu Pro Leu Leu Cys His Ser 
145                 150                 155                 160 


Asp Asn Pro Ser Gln Leu Ile Trp Thr Ser Ser Arg Ser Ala Arg Lys 
                165                 170                 175     


Ser Asn Phe Ser Leu Glu Asp Phe Gln His Ser Lys Gly Lys Glu Pro 
            180                 185                 190         


Tyr Ser Ser Ser Lys Tyr Ala Thr Asp Leu Leu Ser Val Ala Leu Asn 
        195                 200                 205             


Arg Asn Phe Asn Gln Gln Gly Leu Tyr Ser Asn Val Ala Cys Pro Gly 
    210                 215                 220                 


Thr Ala Leu Thr Asn 
225                 


<210>  2311
<211>  384
<212>  PRT
<213>  Homo Sapiens

<400>  2311

His Phe Asp Cys Ser Gly Lys Tyr Arg Cys Arg Ser Ser Phe Lys Cys 
1               5                   10                  15      


Ile Glu Leu Ile Ala Arg Cys Asp Gly Val Ser Asp Cys Lys Asp Gly 
            20                  25                  30          


Glu Asp Glu Tyr Arg Cys Val Arg Val Gly Gly Gln Asn Ala Val Leu 
        35                  40                  45              


Gln Val Phe Thr Ala Ala Ser Trp Lys Thr Met Cys Ser Asp Asp Trp 
    50                  55                  60                  


Lys Gly His Tyr Ala Asn Val Ala Cys Ala Gln Leu Gly Phe Pro Ser 
65                  70                  75                  80  


Tyr Val Ser Ser Asp Asn Leu Arg Val Ser Ser Leu Glu Gly Gln Phe 
                85                  90                  95      


Arg Glu Glu Phe Val Ser Ile Asp His Leu Leu Pro Asp Asp Lys Val 
            100                 105                 110         


Thr Ala Leu His His Ser Val Tyr Val Arg Glu Gly Cys Ala Ser Gly 
        115                 120                 125             


His Val Val Thr Leu Gln Cys Thr Ala Cys Gly His Arg Arg Gly Tyr 
    130                 135                 140                 


Ser Ser Arg Ile Val Gly Gly Asn Met Ser Leu Leu Ser Gln Trp Pro 
145                 150                 155                 160 


Trp Gln Ala Ser Leu Gln Phe Gln Gly Tyr His Leu Cys Gly Gly Ser 
                165                 170                 175     


Val Ile Thr Pro Leu Trp Ile Ile Thr Ala Ala His Cys Val Tyr Asp 
            180                 185                 190         


Leu Tyr Leu Pro Lys Ser Trp Thr Ile Gln Val Gly Leu Val Ser Leu 
        195                 200                 205             


Leu Asp Asn Pro Ala Pro Ser His Leu Val Glu Lys Ile Val Tyr His 
    210                 215                 220                 


Ser Lys Tyr Lys Pro Lys Arg Leu Gly Asn Asp Ile Ala Leu Met Lys 
225                 230                 235                 240 


Leu Ala Gly Pro Leu Thr Phe Asn Glu Met Ile Gln Pro Val Cys Leu 
                245                 250                 255     


Pro Asn Ser Glu Glu Asn Phe Pro Asp Gly Lys Val Cys Trp Thr Ser 
            260                 265                 270         


Gly Trp Gly Ala Thr Glu Asp Gly Gly Asp Ala Ser Pro Val Leu Asn 
        275                 280                 285             


His Ala Ala Val Pro Leu Ile Ser Asn Lys Ile Cys Asn His Arg Asp 
    290                 295                 300                 


Val Tyr Gly Gly Ile Ile Ser Pro Ser Met Leu Cys Ala Gly Tyr Leu 
305                 310                 315                 320 


Thr Gly Gly Val Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu Val 
                325                 330                 335     


Cys Gln Glu Arg Arg Leu Trp Lys Leu Val Gly Ala Thr Ser Phe Gly 
            340                 345                 350         


Ile Gly Cys Ala Glu Val Asn Lys Pro Gly Val Tyr Thr Arg Val Thr 
        355                 360                 365             


Ser Phe Leu Asp Trp Ile His Glu Gln Met Glu Arg Asp Leu Lys Thr 
    370                 375                 380                 


<210>  2312
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2312

Ser Trp Lys Thr Ser Ser Tyr Val Gly Ala Ser Ile Val Thr Ala Val 
1               5                   10                  15      


Gly Phe Ser Lys Gly Leu Trp Met Glu Cys Ala Thr His Ser Thr Gly 
            20                  25                  30          


Ile Thr Gln Cys Asp Ile Tyr Ser Thr Leu Leu Gly Leu Pro Ala Asp 
        35                  40                  45              


Ile Gln Ala Ala Gln 
    50              


<210>  2313
<211>  66
<212>  PRT
<213>  Homo Sapiens

<400>  2313

Ser Glu Ala Ala Ser Leu Ser Pro Lys Lys Val Asp Cys Ser Ile Tyr 
1               5                   10                  15      


Lys Lys Tyr Pro Val Val Ala Ile Pro Cys Pro Ile Thr Tyr Leu Pro 
            20                  25                  30          


Val Cys Gly Ser Asp Tyr Ile Thr Tyr Gly Asn Glu Cys His Leu Cys 
        35                  40                  45              


Thr Glu Ser Leu Lys Ser Asn Gly Arg Val Gln Phe Leu His Asp Gly 
    50                  55                  60                  


Ser Cys 
65      


<210>  2314
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  2314

Thr Pro Thr Cys Glu Pro Ala Thr Pro Leu Cys Cys Arg Arg Asp His 
1               5                   10                  15      


Tyr Val Asp Phe Gln Glu Leu Gly Trp Arg Asp Trp Ile Leu Gln Pro 
            20                  25                  30          


Glu Gly Tyr Gln Leu Asn Tyr Cys Ser Gly Gln Cys Pro Pro His Leu 
        35                  40                  45              


Ala Gly Ser Pro Gly Ile Ala Ala Ser Phe His Ser Ala Val Phe Ser 
    50                  55                  60                  


Leu Leu Lys Ala Asn Asn Pro Trp Pro Ala Ser Thr Ser Cys Cys Val 
65                  70                  75                  80  


Pro Thr Ala Arg Arg Pro Leu Ser Leu Leu Tyr Leu Asp His Asn Gly 
                85                  90                  95      


Asn Val Val Lys Thr Asp Val Pro Asp Met Val Val Glu Ala Cys Gly 
            100                 105                 110         


Cys Ser 
        


<210>  2315
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  2315

Ala Val Ile Thr Gly Ala Cys Glu Arg Asp Val Gln Cys Gly Ala Gly 
1               5                   10                  15      


Thr Cys Cys Ala Ile Ser Leu Trp Leu Arg Gly Leu Arg Met Cys Thr 
            20                  25                  30          


Pro Leu Gly Arg Glu Gly Glu Glu Cys His Pro Gly Ser His Lys Ile 
        35                  40                  45              


Pro Phe Phe Arg Lys Arg Lys His His Thr Cys Pro Cys Leu Pro Asn 
    50                  55                  60                  


Leu Leu Cys Ser Arg Phe Pro Asp Gly Arg Tyr Arg Cys Ser Met Asp 
65                  70                  75                  80  


Leu Lys Asn Ile Asn Phe 
                85      


<210>  2316
<211>  250
<212>  PRT
<213>  Homo Sapiens

<400>  2316

Ala Asn Leu Thr Asn Gly Gly Lys Ser Glu Leu Leu Lys Ser Gly Ser 
1               5                   10                  15      


Ser Lys Ser Thr Leu Lys His Ile Trp Thr Glu Ser Ser Lys Asp Leu 
            20                  25                  30          


Ser Ile Ser Arg Leu Leu Ser Gln Thr Phe Arg Gly Lys Glu Asn Asp 
        35                  40                  45              


Thr Asp Leu Asp Leu Arg Tyr Asp Thr Pro Glu Pro Tyr Ser Glu Gln 
    50                  55                  60                  


Asp Leu Trp Asp Trp Leu Arg Asn Ser Thr Asp Leu Gln Glu Pro Arg 
65                  70                  75                  80  


Pro Arg Ala Lys Arg Arg Pro Ile Val Lys Thr Gly Lys Phe Lys Lys 
                85                  90                  95      


Met Phe Gly Trp Gly Asp Phe His Ser Asn Ile Lys Thr Val Lys Leu 
            100                 105                 110         


Asn Leu Leu Ile Thr Gly Lys Ile Val Asp His Gly Asn Gly Thr Phe 
        115                 120                 125             


Ser Val Tyr Phe Arg His Asn Ser Thr Gly Gln Gly Asn Val Ser Val 
    130                 135                 140                 


Ser Leu Val Pro Pro Thr Lys Ile Val Glu Phe Asp Leu Ala Gln Gln 
145                 150                 155                 160 


Thr Val Ile Asp Ala Lys Asp Ser Lys Ser Phe Asn Cys Arg Ile Glu 
                165                 170                 175     


Tyr Glu Lys Val Asp Lys Ala Thr Lys Asn Thr Leu Cys Asn Tyr Asp 
            180                 185                 190         


Pro Ser Lys Thr Cys Tyr Gln Glu Gln Thr Gln Ser His Val Ser Trp 
        195                 200                 205             


Leu Cys Ser Lys Pro Phe Lys Val Ile Cys Ile Tyr Ile Ser Phe Tyr 
    210                 215                 220                 


Ser Thr Asp Tyr Lys Leu Val Gln Lys Val Cys Pro Asp Tyr Asn Tyr 
225                 230                 235                 240 


His Ser Asp Thr Pro Tyr Phe Pro Ser Gly 
                245                 250 


<210>  2317
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  2317

Glu Leu Ile Pro Asp Ala Pro Leu Ser Ser Ala Ala Tyr Ser Ile Arg 
1               5                   10                  15      


Ser Ile Gly Glu Arg Pro Val Leu Lys Ala Pro Val Pro Lys Arg Gln 
            20                  25                  30          


Lys Cys Asp His Trp Thr Pro Cys Pro Ser Asp Thr Tyr Ala Tyr Arg 
        35                  40                  45              


Leu Leu Ser Gly Gly Gly Arg Ser Lys Tyr Ala Lys Ile Cys Phe Glu 
    50                  55                  60                  


Asp Asn Leu Leu Met Gly Glu Gln Leu Gly Asn Val Ala Arg Gly Ile 
65                  70                  75                  80  


Asn Ile Ala Ile Val Asn Tyr Val Thr Gly Asn Val Thr Ala Thr Arg 
                85                  90                  95      


Cys Phe Asp Met Tyr Glu Gly Asp Asn Ser Gly Pro Met Thr Lys Phe 
            100                 105                 110         


Ile Gln Ser Ala Ala Pro Lys Ser Leu Leu Phe Met Val Thr Tyr Asp 
        115                 120                 125             


Asp Gly Ser Thr Arg Leu Asn Asn Asp Ala Lys Asn Ala Ile Glu Ala 
    130                 135                 140                 


Leu Gly Ser Lys Glu Ile Arg Asn Met Lys Phe Arg Ser Ser Trp Val 
145                 150                 155                 160 


Phe Ile Ala Ala Lys Gly Leu Glu Leu Pro Ser Glu Ile Gln Arg Glu 
                165                 170                 175     


Lys Ile Asn His Ser Asp Ala Lys Asn Asn Arg Tyr Ser Gly Trp Pro 
            180                 185                 190         


Ala Glu Ile Gln Ile Glu Gly Cys Ile Pro Lys Glu Arg Ser 
        195                 200                 205     


<210>  2318
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  2318

Leu Thr Asp Phe Ser Gly Tyr Leu Thr Lys Leu Leu Gln Asn His Thr 
1               5                   10                  15      


Thr Tyr Ala Cys Asp Gly Asp Tyr Leu Asn Leu Gln Cys Pro Arg His 
            20                  25                  30          


Ser Thr Ile Ser Val Gln Ser Ala Phe Tyr Gly Gln Asp Tyr Gln Met 
        35                  40                  45              


Cys Ser Ser Gln Lys Pro Ala Ser Gln Arg Glu Asp Ser Leu Thr Cys 
    50                  55                  60                  


Val Ala Ala Thr Thr Phe Gln Lys Val Leu Asp Glu Cys Gln Asn Gln 
65                  70                  75                  80  


Arg Ala Cys His Leu Leu Val Asn Ser Arg Val Phe Gly Pro Asp Leu 
                85                  90                  95      


Cys Pro Gly Ser Ser Lys Tyr Leu Leu Val Ser Phe Lys Cys Gln Pro 
            100                 105                 110         


Asn Glu Leu Lys Asn Lys Thr Val Cys Glu Asp Gln Glu Leu Lys Leu 
        115                 120                 125             


His Cys His Glu Ser Lys Phe Leu Asn Ile Tyr Ser Ala Thr Tyr Gly 
    130                 135                 140                 


Arg Arg Thr Gln Glu Arg Asp Ile Cys Ser Ser Lys Ala Glu Arg Leu 
145                 150                 155                 160 


Pro Pro Phe Asp Cys Leu Ser Tyr Ser Ala Leu Gln Val Leu Ser Arg 
                165                 170                 175     


Arg Cys Tyr Gly Lys Gln Arg Cys Lys Ile Ile Val Asn Asn His His 
            180                 185                 190         


Phe Gly Ser Pro Cys Leu Pro Gly Val Lys Lys Tyr Leu Thr Val Thr 
        195                 200                 205             


Tyr Ala Cys Val Pro Lys Asn Ile Leu Thr Ala Ile Asp Pro Ala Ile 
    210                 215                 220                 


Ala Asn Leu Lys Pro Ser Leu Lys Gln Lys Asp Gly Ile Asn Phe Asp 
225                 230                 235                 240 


Pro Ser Gly Ser Lys Val Leu Arg Lys Asp Gly Ile Leu Val Ser Asn 
                245                 250                 255     


Ser Leu Ala Ala Phe Ala Tyr Ile Arg Ala His Pro Glu Arg Ala 
            260                 265                 270     


<210>  2319
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  2319

Asp Ile Pro Glu Val Val Val Ser Leu Ala Trp Asp Glu Ser Leu Ala 
1               5                   10                  15      


Pro Lys His Pro Gly Ser Arg Lys Asn Met Ala Cys Tyr Cys Arg Ile 
            20                  25                  30          


Pro Ala Cys Ile Ala Gly Glu Arg Arg Tyr Gly Thr Cys Ile Tyr Gln 
        35                  40                  45              


Gly Arg Leu Trp Ala Phe Cys Cys 
    50                  55      


<210>  2320
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  2320

Cys Gln Glu Leu Leu Glu Thr Val Gly Thr Leu Ala Arg Ile Asp Lys 
1               5                   10                  15      


Asp Glu Leu Gly Lys Ala Ile Gln Asn Ser Leu Val Gly Glu Pro Ile 
            20                  25                  30          


Leu Gln Asn Val Leu Gly Ser Val Thr Ala Val Asn Arg Gly Leu Leu 
        35                  40                  45              


Gly Ser Gly Gly Leu Leu Gly Gly Gly Gly Leu Leu Gly His Gly Gly 
    50                  55                  60                  


Val Phe Gly Val Val Glu Glu Leu Ser Gly Leu Lys Ile Glu Glu Leu 
65                  70                  75                  80  


Thr Leu Pro Lys Val Leu Leu Lys Leu Leu Pro Gly Phe Gly Val Gln 
                85                  90                  95      


Leu Ser Leu His Thr Lys Val Gly Met His Cys Ser Gly Pro Leu Gly 
            100                 105                 110         


Gly Leu Leu Gln Leu Ala Ala Glu Val Asn Val Thr Ser Arg Val Ala 
        115                 120                 125             


Leu Ala Val Ser Ser Arg Gly Thr Pro Ile Leu Ile Leu Lys Arg Cys 
    130                 135                 140                 


Ser Thr Leu Leu Gly His Ile Ser Leu Phe Ser Gly Leu Leu Pro Thr 
145                 150                 155                 160 


Pro Leu Phe Gly Val Val Glu Gln Met Leu Phe Lys Val Leu Pro Gly 
                165                 170                 175     


Leu Leu Cys Pro Val Val Asp Ser Val Leu Gly Val Val Asn Glu Leu 
            180                 185                 190         


Leu Gly Ala Val Leu Gly Leu Val Ser Leu Gly Ala Leu Gly Ser Val 
        195                 200                 205             


Glu Phe Ser Leu Ala Thr Leu Pro Leu Ile Ser Asn Gln Tyr Ile Glu 
    210                 215                 220                 


Leu Asp Ile Asn Pro Ile Val Lys Ser Val Ala Gly Asp Ile Ile Asp 
225                 230                 235                 240 


Phe Pro Lys Ser Arg Ala Pro Ala Lys Val Pro Pro Lys Lys Asp His 
                245                 250                 255     


Thr Ser Gln Val Met Val Pro Leu Tyr Leu Phe Asn Thr Met Phe Gly 
            260                 265                 270         


Leu Leu Gln Thr Asn Gly Ala Leu Asp Met Asp Ile Thr Pro Glu Leu 
        275                 280                 285             


Val Pro Ser Asp Val Pro Leu Thr Thr Thr Asp Leu Ala Ala Leu Leu 
    290                 295                 300                 


Pro Glu Ala Leu Gly Lys Leu Pro Leu His Gln Gln Leu Leu Leu Phe 
305                 310                 315                 320 


Leu Arg Val Arg Glu Ala Pro Thr Val Thr Leu His Asn Lys Lys Ala 
                325                 330                 335     


Leu Val Ser Leu Pro Ala Asn Ile His Val Leu Phe Tyr Val Pro Lys 
            340                 345                 350         


Gly Thr Pro Glu Ser Leu Phe Glu Leu Asn Ser Val Met Thr Val Arg 
        355                 360                 365             


Ala Gln Leu Ala Pro Ser Ala Thr Lys Leu His Ile Ser Leu Ser Leu 
    370                 375                 380                 


Glu Arg Leu Ser Val Lys Val Ala Ser Ser Phe Thr His Ala Phe Asp 
385                 390                 395                 400 


Gly Ser Arg Leu Glu Glu Trp Leu Ser His Val Val Gly Ala Val Tyr 
                405                 410                 415     


Ala Pro Lys Leu Asn Val Ala Leu Asp Val Gly Ile Ser Leu Pro Lys 
            420                 425                 430         


Val Leu Asn Ile Asn Phe Ser Asn Ser Val Leu Glu Ile Val Glu Asn 
        435                 440                 445             


Ala Val Val Leu Thr Val Ala Ser 
    450                 455     


<210>  2321
<211>  179
<212>  PRT
<213>  Homo Sapiens

<400>  2321

Gln Glu Val Asp Thr Asp Phe Asp Phe Pro Glu Glu Asp Lys Lys Glu 
1               5                   10                  15      


Glu Phe Glu Glu Cys Leu Glu Lys Phe Phe Ser Thr Gly Pro Ala Arg 
            20                  25                  30          


Pro Pro Thr Lys Glu Lys Val Lys Arg Arg Val Leu Ile Glu Pro Gly 
        35                  40                  45              


Met Pro Leu Asn His Ile Glu Tyr Cys Asn His Glu Ile Met Gly Lys 
    50                  55                  60                  


Asn Val Tyr Tyr Lys His Arg Trp Val Ala Glu His Tyr Phe Leu Leu 
65                  70                  75                  80  


Met Gln Tyr Asp Glu Leu Gln Lys Ile Cys Tyr Asn Arg Phe Val Pro 
                85                  90                  95      


Cys Lys Asn Gly Ile Arg Lys Cys Asn Arg Ser Lys Gly Leu Val Glu 
            100                 105                 110         


Gly Val Tyr Cys Asn Leu Thr Glu Ala Ser Glu Ile Pro Ala Cys Lys 
        115                 120                 125             


Tyr Glu Ser Leu Tyr Arg Lys Gly Tyr Val Leu Ile Thr Cys Ser Trp 
    130                 135                 140                 


Gln Asn Glu Met Gln Lys Arg Ile Pro His Thr Ile Asn Asp Leu Val 
145                 150                 155                 160 


Glu Pro Pro Glu His Arg Ser Phe Leu Ser Glu Asp Gly Val Phe Val 
                165                 170                 175     


Ile Pro Pro 
            


<210>  2322
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  2322

Ala Tyr Arg His Pro Asp Phe Pro Leu Leu Glu Lys Ala Gln Gln Leu 
1               5                   10                  15      


Leu Gln Ser Thr Gly Ser Pro Tyr Ser Thr Asn Cys Trp Leu Cys Thr 
            20                  25                  30          


Ser Ser Ser Thr Glu Thr Pro Gly Thr Ala Tyr Pro Ala Ser Pro Arg 
        35                  40                  45              


Glu Trp Thr Ser Ile Glu Ala Glu Leu His Ile Ser Tyr Arg Trp Asp 
    50                  55                  60                  


Pro Asn Leu Lys Gly Leu Met Arg Pro Ala Asn Ser Leu Leu Ser Thr 
65                  70                  75                  80  


Val Lys Gln Asp Phe Pro Asp Ile Arg Gln Lys Pro Pro Ile Phe Gly 
                85                  90                  95      


Pro Ile Phe Thr Asn Ile Asn Leu Met Gly Ile Ala Pro Ile Cys Val 
            100                 105                 110         


Met Ala Lys Arg Lys Asn Gly Thr Asn Val Gly Thr Leu Pro Ser Thr 
        115                 120                 125             


Val Cys Asn Val Thr Phe Thr Val Asp Ser Asn Gln Gln Thr Tyr Gln 
    130                 135                 140                 


Thr Tyr Thr His Asn Gln Phe Arg His Gln Pro Arg Phe Pro Lys Pro 
145                 150                 155                 160 


Pro Asn Ile Thr Phe Pro Gln Gly Thr Leu Leu Asp Lys Ser Ser Arg 
                165                 170                 175     


Phe Cys Gln Gly Arg Pro Ser Ser Cys Ser Thr Arg Asn Phe Trp Phe 
            180                 185                 190         


Arg Pro Ala Asp Tyr Asn Gln Cys Leu Gln Ile Ser Asn Leu Ser Ser 
        195                 200                 205             


Thr Ala Glu Trp Val Leu Leu Asp Gln Thr Arg Asn Ser Leu Phe Trp 
    210                 215                 220                 


Glu Asn Lys Thr Lys Gly Ala Asn Gln Ser Gln Thr Pro Cys Val Gln 
225                 230                 235                 240 


Val Leu Ala Gly Met Thr Ile Ala Thr Ser Tyr Leu Gly Ile Ser Ala 
                245                 250                 255     


Val Ser Glu Phe Phe Gly Thr Ser Leu Thr Pro Leu Phe His Phe His 
            260                 265                 270         


Ile Ser Thr Cys Leu Lys Thr Gln Gly Ala Phe Tyr Ile Cys Gly Gln 
        275                 280                 285             


Ser Ile His Gln Cys Leu Pro Ser Asn Trp Thr Gly Thr Cys Thr Ile 
    290                 295                 300                 


Gly Tyr Val Thr Pro Asp Ile Phe Ile Ala Pro Gly Asn Leu Ser Leu 
305                 310                 315                 320 


Pro Ile Pro Ile Tyr Gly Asn Ser Pro Leu Pro Arg Val Arg Arg Ala 
                325                 330                 335     


Ile His Phe Ile Pro Leu Leu Ala Gly Leu Gly Ile Leu Ala Gly Thr 
            340                 345                 350         


Gly Thr Gly Ile Ala Gly Ile Thr Lys Ala Ser Leu Thr Tyr Ser Gln 
        355                 360                 365             


Leu Ser Lys Glu Ile Ala Asn Asn Ile Asp Thr Met Ala Lys Ala Leu 
    370                 375                 380                 


Thr Thr Met Gln Glu Gln Ile Asp Ser Leu Ala Ala Val Val Leu Gln 
385                 390                 395                 400 


Asn Arg Arg Gly Leu Asp Met Leu Thr Ala Ala Gln Gly Gly Ile Cys 
                405                 410                 415     


Leu Ala Leu Asp Glu Lys Cys Cys Phe Trp Val Asn Gln Ser Gly Lys 
            420                 425                 430         


Val Gln Asp Asn Ile Arg Gln Leu Leu Asn Gln Ala Ser Ser Leu Arg 
        435                 440                 445             


Glu Arg Ala Thr Gln Gly Trp Leu Asn Trp Glu Gly Thr Trp Lys 
    450                 455                 460             


<210>  2323
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  2323

Trp Pro Gly Leu Pro Arg Arg Pro Cys Val His Cys Cys Arg Pro Ala 
1               5                   10                  15      


Trp Pro Pro Gly Pro Tyr Ala Arg Val Ser Asp Arg Asp Leu Trp Arg 
            20                  25                  30          


Gly Asp Leu Trp Arg Gly Leu Pro Arg Val Arg Pro Thr Ile Asp Ile 
        35                  40                  45              


Glu Ile Leu Lys Gly Glu Lys Gly Glu Ala Gly Val Arg Gly Arg Ala 
    50                  55                  60                  


Gly Arg Ser Gly Lys Glu Gly Pro Pro Gly Ala Arg Gly Leu Gln Gly 
65                  70                  75                  80  


Arg Arg Gly Gln Lys Gly Gln Val Gly Pro Pro Gly Ala Ala Cys Arg 
                85                  90                  95      


Arg Ala Tyr Ala Ala Phe Ser Val Gly Arg Arg Glu Gly Leu His Ser 
            100                 105                 110         


Ser Asp His Phe Gln Ala Val Pro Phe Asp Thr Glu Leu Val Asn Leu 
        115                 120                 125             


Asp Gly Ala Phe Asp Leu Ala Ala Gly Arg Phe Leu Cys Thr Val Pro 
    130                 135                 140                 


Gly Val Tyr Phe Leu Ser Leu Asn Val His Thr Trp Asn Tyr Lys Glu 
145                 150                 155                 160 


Thr Tyr Leu His Ile Met Leu Asn Arg Arg Pro Ala Ala Val Leu Tyr 
                165                 170                 175     


Ala Gln Pro Ser Glu Arg Ser Val Met Gln Ala Gln Ser Leu Met Leu 
            180                 185                 190         


Leu Leu Ala Ala Gly Asp Ala Val Trp Val Arg Met Phe Gln Arg Asp 
        195                 200                 205             


Arg Asp Asn Ala Ile Tyr Gly Glu His Gly Asp Leu Tyr Ile Thr Phe 
    210                 215                 220                 


Ser Gly His Leu Val Lys Pro Ala Ala Glu Leu 
225                 230                 235 


<210>  2324
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2324

Ala Thr Leu Gly Gly Pro Glu Glu Glu Ser Thr Ile Glu Asn Tyr Ala 
1               5                   10                  15      


Ser Arg Pro Glu Ala Phe Asn Thr Pro Phe Leu Asn Ile Asp Lys Leu 
            20                  25                  30          


Arg Ser Ala Phe Lys Ala Asp Glu Phe Leu Asn Trp His Ala Leu Phe 
        35                  40                  45              


Glu Ser Ile Lys Arg Lys Leu Pro Phe Leu Asn Trp Asp Ala Phe Pro 
    50                  55                  60                  


Lys Leu Lys Gly Leu Arg Ser Ala Thr Pro Asp Ala Gln 
65                  70                  75          


<210>  2325
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  2325

Val Asp Val Thr Thr Thr Glu Ala Phe Asp Ser Gly Val Ile Asp Val 
1               5                   10                  15      


Gln Ser Thr Pro Thr Val Arg Glu Glu Lys Ser Ala Thr Asp Leu Thr 
            20                  25                  30          


Ala Lys Leu Leu Leu Leu Asp Glu Leu Val Ser Leu Glu Asn Asp Val 
        35                  40                  45              


Ile Glu Thr Lys Lys Lys Arg Ser Phe Ser Gly Phe Gly Ser Pro Leu 
    50                  55                  60                  


Asp Arg Leu Ser Ala Gly Ser Val Asp His Lys Gly Lys Gln Arg Lys 
65                  70                  75                  80  


Val Val Asp His Pro Lys Arg Arg Phe Gly Ile Pro Met Asp Arg Ile 
                85                  90                  95      


Gly Arg Asn Arg Leu Ser Asn Ser Arg Gly 
            100                 105     


<210>  2326
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  2326

Lys Val Phe Glu Arg Cys Glu Leu Ala Arg Thr Leu Lys Arg Leu Gly 
1               5                   10                  15      


Met Asp Gly Tyr Arg Gly Ile Ser Leu Ala Asn Trp Met Cys Leu Ala 
            20                  25                  30          


Lys Trp Glu Ser Gly Tyr Asn Thr Arg Ala Thr Asn Tyr Asn Ala Gly 
        35                  40                  45              


Asp Arg Ser Thr Asp Tyr Gly Ile Phe Gln Ile Asn Ser Arg Tyr Trp 
    50                  55                  60                  


Cys Asn Asp Gly Lys Thr Pro Gly Ala Val Asn Ala Cys His Leu Ser 
65                  70                  75                  80  


Cys Ser Ala Leu Leu Gln Asp Asn Ile Ala Asp Ala Val Ala Cys Ala 
                85                  90                  95      


Lys Arg Val Val Arg Asp Pro Gln Gly Ile Arg Ala Trp Val Ala Trp 
            100                 105                 110         


Arg Asn Arg Cys Gln Asn Arg Asp Val Arg Gln Tyr Val Gln Gly Cys 
        115                 120                 125             


Gly Val 
    130 


<210>  2327
<211>  132
<212>  PRT
<213>  Homo Sapiens

<400>  2327

Glu Pro Val Gln Phe Lys Asp Cys Gly Ser Val Asp Gly Val Ile Lys 
1               5                   10                  15      


Glu Val Asn Val Ser Pro Cys Pro Thr Gln Pro Cys Gln Leu Ser Lys 
            20                  25                  30          


Gly Gln Ser Tyr Ser Val Asn Val Thr Phe Thr Ser Asn Ile Gln Ser 
        35                  40                  45              


Lys Ser Ser Lys Ala Val Val His Gly Ile Leu Met Gly Val Pro Val 
    50                  55                  60                  


Pro Phe Pro Ile Pro Glu Pro Asp Gly Cys Lys Ser Gly Ile Asn Cys 
65                  70                  75                  80  


Pro Ile Gln Lys Asp Lys Thr Tyr Ser Tyr Leu Asn Lys Leu Pro Val 
                85                  90                  95      


Lys Ser Glu Tyr Pro Ser Ile Lys Leu Val Val Glu Trp Gln Leu Gln 
            100                 105                 110         


Asp Asp Lys Asn Gln Ser Leu Phe Cys Trp Glu Ile Pro Val Gln Ile 
        115                 120                 125             


Val Ser His Leu 
    130         


<210>  2328
<211>  143
<212>  PRT
<213>  Homo Sapiens

<400>  2328

Val Trp Leu Gly Arg Leu Asp Pro Glu Gln Leu Leu Gly Pro Trp Tyr 
1               5                   10                  15      


Val Leu Ala Val Ala Ser Arg Glu Lys Gly Phe Ala Met Glu Lys Asp 
            20                  25                  30          


Met Lys Asn Val Val Gly Val Val Val Thr Leu Thr Pro Glu Asn Asn 
        35                  40                  45              


Leu Arg Thr Leu Ser Ser Gln His Gly Leu Gly Gly Cys Asp Gln Ser 
    50                  55                  60                  


Val Met Asp Leu Ile Lys Arg Asn Ser Gly Trp Val Phe Glu Asn Pro 
65                  70                  75                  80  


Ser Ile Gly Val Leu Glu Leu Trp Val Leu Ala Thr Asn Phe Arg Asp 
                85                  90                  95      


Tyr Ala Ile Ile Phe Thr Gln Leu Glu Phe Gly Asp Glu Pro Phe Asn 
            100                 105                 110         


Thr Val Glu Leu Tyr Ser Leu Thr Glu Thr Ala Ser Gln Glu Ala Met 
        115                 120                 125             


Gly Leu Phe Thr Lys Trp Ser Arg Ser Leu Gly Phe Leu Ser Gln 
    130                 135                 140             


<210>  2329
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  2329

Val Asn Pro Thr Val Phe Phe Asp Ile Ala Val Asp Gly Glu Pro Leu 
1               5                   10                  15      


Gly Arg Val Ser Phe Glu Leu Phe Ala Asp Lys Val Pro Lys Thr Ala 
            20                  25                  30          


Glu Asn Phe Arg Ala Leu Ser Thr Gly Glu Lys Gly Phe Gly Tyr Lys 
        35                  40                  45              


Gly Ser Cys Phe His Arg Ile Ile Pro Gly Phe Met Cys Gln Gly Gly 
    50                  55                  60                  


Asp Phe Thr Arg His Asn Gly Thr Gly Gly Lys Ser Ile Tyr Gly Glu 
65                  70                  75                  80  


Lys Phe Glu Asp Glu Asn Phe Ile Leu Lys His Thr Gly Pro Gly Ile 
                85                  90                  95      


Leu Ser Met Ala Asn Ala Gly Pro Asn Thr Asn Gly Ser Gln Phe Phe 
            100                 105                 110         


Ile Cys Thr Ala Lys Thr Glu Trp Leu Asp Gly Lys His Val Val Phe 
        115                 120                 125             


Gly Lys Val Lys Glu Gly Met Asn Ile Val Glu Ala Met Glu Arg Phe 
    130                 135                 140                 


Gly Ser Arg Asn Gly Lys Thr Ser Lys Lys Ile Thr Ile Ala Asp Cys 
145                 150                 155                 160 


Gly Gln Leu Glu 
                


<210>  2330
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  2330

Ser Ser Glu Ala Glu Thr Gln Gln Pro Pro Ala Ala Pro Pro Ala Ala 
1               5                   10                  15      


Pro Ala Leu Ser Ala Ala Asp Thr Lys Pro Gly Thr Thr Gly Ser Gly 
            20                  25                  30          


Ala Gly Ser Gly Gly Pro Gly Gly Leu Thr Ser Ala Ala Pro Ala Gly 
        35                  40                  45              


Gly Asp Lys Lys Val Ile Ala Thr Lys Val Leu Gly Thr Val Lys Trp 
    50                  55                  60                  


Phe Asn Val Arg Asn Gly Tyr Gly Phe Ile Asn Arg Asn Asp Thr Lys 
65                  70                  75                  80  


Glu Asp Val Phe Val His Gln Thr Ala Ile Lys Lys Asn Asn Pro Arg 
                85                  90                  95      


Lys Tyr Leu Arg Ser Val Gly Asp Gly Glu Thr Val Glu Phe Asp Val 
            100                 105                 110         


Val Glu Gly Glu Lys Gly Ala Glu Ala Ala Asn Val Thr Gly Pro Gly 
        115                 120                 125             


Gly Val Pro Val Gln Gly Ser Lys Tyr Ala Ala Asp Arg Asn His Tyr 
    130                 135                 140                 


Arg Arg Tyr Pro Arg Arg Arg Gly Pro Pro Arg Asn Tyr Gln Gln Asn 
145                 150                 155                 160 


Tyr Gln Asn Ser Glu Ser Gly Glu Lys Asn Glu Gly Ser Glu Ser Ala 
                165                 170                 175     


Pro Glu Gly Gln Ala Gln Gln Arg Arg Pro Tyr Arg Arg Arg Arg Phe 
            180                 185                 190         


Pro Pro Tyr Tyr Met Arg Arg Pro Tyr Gly Arg Arg Pro Gln Tyr Ser 
        195                 200                 205             


Asn Pro Pro Val Gln Gly Glu Val Met Glu Gly Ala Asp Asn Gln Gly 
    210                 215                 220                 


Ala Gly Glu Gln Gly Arg Pro Val Arg Gln Asn Met Tyr Arg Gly Tyr 
225                 230                 235                 240 


Arg Pro Arg Phe Arg Arg Gly Pro Pro Arg Gln Arg Gln Pro Arg Glu 
                245                 250                 255     


Asp Gly Asn Glu Glu Asp Lys Glu Asn Gln Gly Asp Glu Thr Gln Gly 
            260                 265                 270         


Gln Gln Pro Pro Gln Arg Arg Tyr Arg Arg Asn Phe Asn Tyr Arg Arg 
        275                 280                 285             


Arg Arg Pro Glu Asn Pro Lys Pro Gln Asp Gly Lys Glu Thr Lys Ala 
    290                 295                 300                 


Ala Asp Pro Pro Ala Glu Asn Ser Ser Ala Pro Glu Ala Glu Gln Gly 
305                 310                 315                 320 


Gly Ala Glu 
            


<210>  2331
<211>  522
<212>  PRT
<213>  Homo Sapiens

<400>  2331

Glu Gly Val Gln Thr Cys Glu Glu Val Arg Lys Leu Phe Gln Trp Arg 
1               5                   10                  15      


Leu Leu Gly Ala Val Arg Gly Leu Pro Asp Ser Pro Arg Ala Gly Pro 
            20                  25                  30          


Asp Leu Gln Val Cys Ile Ser Lys Lys Pro Thr Cys Cys Thr Arg Lys 
        35                  40                  45              


Met Glu Glu Arg Tyr Gln Ile Ala Ala Arg Gln Asp Met Gln Gln Phe 
    50                  55                  60                  


Leu Gln Thr Ser Ser Ser Thr Leu Lys Phe Leu Ile Ser Arg Asn Ala 
65                  70                  75                  80  


Ala Ala Phe Gln Glu Thr Leu Glu Thr Leu Ile Lys Gln Ala Glu Asn 
                85                  90                  95      


Tyr Thr Ser Ile Leu Phe Cys Ser Thr Tyr Arg Asn Met Ala Leu Glu 
            100                 105                 110         


Ala Ala Ala Ser Val Gln Glu Phe Phe Thr Asp Val Gly Leu Tyr Leu 
        115                 120                 125             


Phe Gly Ala Asp Val Asn Pro Glu Glu Phe Val Asn Arg Phe Phe Asp 
    130                 135                 140                 


Ser Leu Phe Pro Leu Val Tyr Asn His Leu Ile Asn Pro Gly Val Thr 
145                 150                 155                 160 


Asp Ser Ser Leu Glu Tyr Ser Glu Cys Ile Arg Met Ala Arg Arg Asp 
                165                 170                 175     


Val Ser Pro Phe Gly Asn Ile Pro Gln Arg Val Met Gly Gln Met Gly 
            180                 185                 190         


Arg Ser Leu Leu Pro Ser Arg Thr Phe Leu Gln Ala Leu Asn Leu Gly 
        195                 200                 205             


Ile Glu Val Ile Asn Thr Thr Asp Tyr Leu His Phe Ser Lys Glu Cys 
    210                 215                 220                 


Ser Arg Ala Leu Leu Lys Met Gln Tyr Cys Pro His Cys Gln Gly Leu 
225                 230                 235                 240 


Ala Leu Thr Lys Pro Cys Met Gly Tyr Cys Leu Asn Val Met Arg Gly 
                245                 250                 255     


Cys Leu Ala His Met Ala Glu Leu Asn Pro His Trp His Ala Tyr Ile 
            260                 265                 270         


Arg Ser Leu Glu Glu Leu Ser Asp Ala Met His Gly Thr Tyr Asp Ile 
        275                 280                 285             


Gly His Val Leu Leu Asn Phe His Leu Leu Val Asn Asp Ala Val Leu 
    290                 295                 300                 


Gln Ala His Leu Asn Gly Gln Lys Leu Leu Glu Gln Val Asn Arg Ile 
305                 310                 315                 320 


Cys Gly Arg Pro Val Arg Thr Pro Thr Gln Ser Pro Arg Cys Ser Phe 
                325                 330                 335     


Asp Gln Ser Lys Glu Lys His Gly Met Lys Thr Thr Thr Arg Asn Ser 
            340                 345                 350         


Glu Glu Thr Leu Ala Asn Arg Arg Lys Glu Phe Ile Asn Ser Leu Arg 
        355                 360                 365             


Leu Tyr Arg Ser Phe Tyr Gly Gly Leu Ala Asp Gln Leu Cys Ala Asn 
    370                 375                 380                 


Glu Leu Ala Ala Ala Asp Gly Leu Pro Cys Trp Asn Gly Glu Asp Ile 
385                 390                 395                 400 


Val Lys Ser Tyr Thr Gln Arg Val Val Gly Asn Gly Ile Lys Ala Gln 
                405                 410                 415     


Ser Gly Asn Pro Glu Val Lys Val Lys Gly Ile Asp Pro Val Ile Asn 
            420                 425                 430         


Gln Ile Ile Asp Lys Leu Lys His Val Val Gln Leu Leu Gln Gly Arg 
        435                 440                 445             


Ser Pro Lys Pro Asp Lys Trp Glu Leu Leu Gln Leu Gly Ser Gly Gly 
    450                 455                 460                 


Gly Met Val Glu Gln Val Ser Gly Asp Cys Asp Asp Glu Asp Gly Cys 
465                 470                 475                 480 


Gly Gly Ser Gly Ser Gly Glu Val Lys Arg Thr Leu Lys Ile Thr Asp 
                485                 490                 495     


Trp Met Pro Asp Asp Met Asn Phe Ser Asp Val Lys Gln Ile His Gln 
            500                 505                 510         


Thr Asp Thr Gly Ser Thr Leu Asp Thr Thr 
        515                 520         


<210>  2332
<211>  358
<212>  PRT
<213>  Homo Sapiens

<400>  2332

His Tyr His His Val Thr Lys Leu Asp Glu Val Ala Ala Ser Gln Leu 
1               5                   10                  15      


Thr Phe Pro Ala Val Thr Leu Cys Asn Leu Asn Glu Phe Arg Phe Ser 
            20                  25                  30          


Gln Val Ser Lys Asn Asp Leu Tyr His Ala Gly Glu Leu Leu Ala Leu 
        35                  40                  45              


Leu Asn Asn Arg Tyr Glu Ile Pro Asp Thr Gln Met Ala Asp Glu Lys 
    50                  55                  60                  


Gln Leu Glu Ile Leu Gln Asp Lys Ala Asn Phe Arg Ser Phe Lys Pro 
65                  70                  75                  80  


Lys Pro Phe Asn Met Arg Glu Phe Tyr Asp Arg Ala Gly His Asp Ile 
                85                  90                  95      


Arg Asp Met Leu Leu Ser Cys His Phe Arg Gly Glu Val Cys Ser Ala 
            100                 105                 110         


Glu Asp Phe Lys Val Val Phe Thr Arg Tyr Gly Lys Cys Tyr Thr Phe 
        115                 120                 125             


Asn Ser Gly Arg Asp Gly Arg Pro Arg Leu Lys Thr Met Lys Gly Gly 
    130                 135                 140                 


Thr Gly Asn Gly Leu Glu Ile Met Leu Asp Ile Gln Gln Asp Glu Tyr 
145                 150                 155                 160 


Leu Pro Val Trp Gly Glu Thr Asp Glu Thr Ser Phe Glu Ala Gly Ile 
                165                 170                 175     


Lys Val Gln Ile His Ser Gln Asp Glu Pro Pro Phe Ile Asp Gln Leu 
            180                 185                 190         


Gly Phe Gly Val Ala Pro Gly Phe Gln Thr Phe Val Ala Cys Gln Glu 
        195                 200                 205             


Gln Arg Leu Ile Tyr Leu Pro Pro Pro Trp Gly Thr Cys Lys Ala Val 
    210                 215                 220                 


Thr Met Asp Ser Asp Leu Asp Phe Phe Asp Ser Tyr Ser Ile Thr Ala 
225                 230                 235                 240 


Cys Arg Ile Asp Cys Glu Thr Arg Tyr Leu Val Glu Asn Cys Asn Cys 
                245                 250                 255     


Arg Met Val His Met Pro Gly Asp Ala Pro Tyr Cys Thr Pro Glu Gln 
            260                 265                 270         


Tyr Lys Glu Cys Ala Asp Pro Ala Leu Asp Phe Leu Val Glu Lys Asp 
        275                 280                 285             


Gln Glu Tyr Cys Val Cys Glu Met Pro Cys Asn Leu Thr Arg Tyr Gly 
    290                 295                 300                 


Lys Glu Leu Ser Met Val Lys Ile Pro Ser Lys Ala Ser Ala Lys Tyr 
305                 310                 315                 320 


Leu Ala Lys Lys Phe Asn Lys Ser Glu Gln Tyr Ile Gly Glu Asn Ile 
                325                 330                 335     


Leu Val Leu Asp Ile Phe Phe Glu Val Leu Asn Tyr Glu Thr Ile Glu 
            340                 345                 350         


Gln Lys Lys Ala Tyr Glu 
        355             


<210>  2333
<211>  59
<212>  PRT
<213>  Homo Sapiens

<400>  2333

Ser Ser Thr Leu Pro Thr Asp Tyr Trp Lys Val Ser Thr Ile Asp Gly 
1               5                   10                  15      


Thr Val Ile Thr Thr Ala Thr Tyr Trp Ala Asn Leu Trp Lys Ala Cys 
            20                  25                  30          


Val Thr Asp Ser Thr Gly Val Ser Asn Cys Lys Asp Phe Pro Ser Met 
        35                  40                  45              


Leu Ala Leu Asp Gly Tyr Ile Gln Ala Cys Arg 
    50                  55                  


<210>  2334
<211>  600
<212>  PRT
<213>  Homo Sapiens

<400>  2334

Gln Gly Leu Leu Ser Leu Gln Ala Lys Gln Glu Tyr Cys Leu Lys Pro 
1               5                   10                  15      


Glu Cys Ile Glu Ala Ala Ala Ala Ile Leu Ser Lys Val Asn Leu Ser 
            20                  25                  30          


Val Asp Pro Cys Asp Asn Phe Phe Arg Phe Ala Cys Asp Gly Trp Ile 
        35                  40                  45              


Ser Asn Asn Pro Ile Pro Glu Asp Met Pro Ser Tyr Gly Val Tyr Pro 
    50                  55                  60                  


Trp Leu Arg His Asn Val Asp Leu Lys Leu Lys Glu Leu Leu Glu Lys 
65                  70                  75                  80  


Ser Ile Ser Arg Arg Arg Asp Thr Glu Ala Ile Gln Lys Ala Lys Ile 
                85                  90                  95      


Leu Tyr Ser Ser Cys Met Asn Glu Lys Ala Ile Glu Lys Ala Asp Ala 
            100                 105                 110         


Lys Pro Leu Leu His Ile Leu Arg His Ser Pro Phe Arg Trp Pro Val 
        115                 120                 125             


Leu Glu Ser Asn Ile Gly Pro Glu Gly Val Trp Ser Glu Arg Lys Phe 
    130                 135                 140                 


Ser Leu Leu Gln Thr Leu Ala Thr Phe Arg Gly Gln Tyr Ser Asn Ser 
145                 150                 155                 160 


Val Phe Ile Arg Leu Tyr Val Ser Pro Asp Asp Lys Ala Ser Asn Glu 
                165                 170                 175     


His Ile Leu Lys Leu Asp Gln Ala Thr Leu Ser Leu Ala Val Arg Glu 
            180                 185                 190         


Asp Tyr Leu Asp Asn Ser Thr Glu Ala Lys Ser Tyr Arg Asp Ala Leu 
        195                 200                 205             


Tyr Lys Phe Met Val Asp Thr Ala Val Leu Leu Gly Ala Asn Ser Ser 
    210                 215                 220                 


Arg Ala Glu His Asp Met Lys Ser Val Leu Arg Leu Glu Ile Lys Ile 
225                 230                 235                 240 


Ala Glu Ile Met Ile Pro His Glu Asn Arg Thr Ser Glu Ala Met Tyr 
                245                 250                 255     


Asn Lys Met Asn Ile Ser Glu Leu Ser Ala Met Ile Pro Gln Phe Asp 
            260                 265                 270         


Trp Leu Gly Tyr Ile Lys Lys Val Ile Asp Thr Arg Leu Tyr Pro His 
        275                 280                 285             


Leu Lys Asp Ile Ser Pro Ser Glu Asn Val Val Val Arg Val Pro Gln 
    290                 295                 300                 


Tyr Phe Lys Asp Leu Phe Arg Ile Leu Gly Ser Glu Arg Lys Lys Thr 
305                 310                 315                 320 


Ile Ala Asn Tyr Leu Val Trp Arg Met Val Tyr Ser Arg Ile Pro Asn 
                325                 330                 335     


Leu Ser Arg Arg Phe Gln Tyr Arg Trp Leu Glu Phe Ser Arg Val Ile 
            340                 345                 350         


Gln Gly Thr Thr Thr Leu Leu Pro Gln Trp Asp Lys Cys Val Asn Phe 
        355                 360                 365             


Ile Glu Ser Ala Leu Pro Tyr Val Val Gly Lys Met Phe Val Asp Val 
    370                 375                 380                 


Tyr Phe Gln Glu Asp Lys Lys Glu Met Met Glu Glu Leu Val Glu Gly 
385                 390                 395                 400 


Val Arg Trp Ala Phe Ile Asp Met Leu Glu Lys Glu Asn Glu Trp Met 
                405                 410                 415     


Asp Ala Gly Thr Lys Arg Lys Ala Lys Glu Lys Ala Arg Ala Val Leu 
            420                 425                 430         


Ala Lys Val Gly Tyr Pro Glu Phe Ile Met Asn Asp Thr His Val Asn 
        435                 440                 445             


Glu Asp Leu Lys Ala Ile Lys Phe Ser Glu Ala Asp Tyr Phe Gly Asn 
    450                 455                 460                 


Val Leu Gln Thr Arg Lys Tyr Leu Ala Gln Ser Asp Phe Phe Trp Leu 
465                 470                 475                 480 


Arg Lys Ala Val Pro Lys Thr Glu Trp Phe Thr Asn Pro Thr Thr Val 
                485                 490                 495     


Asn Ala Phe Tyr Ser Ala Ser Thr Asn Gln Ile Arg Phe Pro Ala Gly 
            500                 505                 510         


Glu Leu Gln Lys Pro Phe Phe Trp Gly Thr Glu Tyr Pro Arg Ser Leu 
        515                 520                 525             


Ser Tyr Gly Ala Ile Gly Val Ile Val Gly His Glu Phe Thr His Gly 
    530                 535                 540                 


Phe Asp Asn Asn Gly Arg Lys Tyr Asp Lys Asn Gly Asn Leu Asp Pro 
545                 550                 555                 560 


Trp Trp Ser Thr Glu Ser Glu Glu Lys Phe Lys Glu Lys Thr Lys Cys 
                565                 570                 575     


Met Ile Asn Gln Tyr Ser Asn Tyr Tyr Trp Lys Lys Ala Gly Leu Asn 
            580                 585                 590         


Val Lys Gly Lys Arg Thr Leu Gly 
        595                 600 


<210>  2335
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  2335

Gly Asp Thr Arg Pro Arg Phe Leu Glu Leu Arg Lys Ser Glu Cys His 
1               5                   10                  15      


Phe Phe Asn Gly Thr Glu Arg Val Arg Tyr Leu Asp Arg Tyr Phe His 
            20                  25                  30          


Asn Gln Glu Glu Phe Leu Arg Phe Asp Ser Asp Val Gly Glu Tyr Arg 
        35                  40                  45              


Ala Val Thr Glu Leu Gly Arg Pro Val Ala Glu Ser Trp Asn Ser Gln 
    50                  55                  60                  


Lys Asp Leu Leu Glu Gln Lys Arg Gly Arg Val Asp Asn Tyr Cys Arg 
65                  70                  75                  80  


His Asn Tyr Gly Val Gly Glu Ser Phe Thr Val Gln Arg Arg Val His 
                85                  90                  95      


Pro Gln Val Thr Val Tyr Pro Ala Lys Thr Gln Pro Leu Gln His His 
            100                 105                 110         


Asn Leu Leu Val Cys Ser Val Ser Gly Phe Tyr Pro Gly Ser Ile Glu 
        115                 120                 125             


Val Arg Trp Phe Arg Asn Gly Gln Glu Glu Lys Ala Gly Val Val Ser 
    130                 135                 140                 


Thr Gly Leu Ile Gln Asn Gly Asp Trp Thr Phe Gln Thr Leu Val Met 
145                 150                 155                 160 


Leu Glu Thr Val Pro Arg Ser Gly Glu Val Tyr Thr Cys Gln Val Glu 
                165                 170                 175     


His Pro Ser Val Thr Ser Ala Leu Thr Val Glu Trp Arg Ala Arg Ser 
            180                 185                 190         


Glu Ser Ala Gln Ser Lys 
        195             


<210>  2336
<211>  817
<212>  PRT
<213>  Homo Sapiens

<400>  2336

Cys Gly Leu Ser Thr His Val Glu Ile Gly His Arg Ala Leu Glu Phe 
1               5                   10                  15      


Leu Gln Leu His Asn Gly Arg Val Asn Tyr Arg Glu Leu Leu Leu Glu 
            20                  25                  30          


His Gln Asp Ala Tyr Gln Ala Gly Ile Val Phe Pro Asp Cys Phe Tyr 
        35                  40                  45              


Pro Ser Ile Cys Lys Gly Gly Lys Phe His Asp Val Ser Glu Ser Thr 
    50                  55                  60                  


His Trp Thr Pro Phe Leu Asn Ala Ser Val His Tyr Ile Arg Glu Asn 
65                  70                  75                  80  


Tyr Pro Leu Pro Trp Glu Lys Asp Thr Glu Lys Leu Val Ala Phe Leu 
                85                  90                  95      


Phe Gly Ile Thr Ser His Met Ala Ala Asp Val Ser Trp His Ser Leu 
            100                 105                 110         


Gly Leu Glu Gln Gly Phe Leu Arg Thr Met Gly Ala Ile Asp Phe His 
        115                 120                 125             


Gly Ser Tyr Ser Glu Ala His Ser Ala Gly Asp Phe Gly Gly Asp Val 
    130                 135                 140                 


Leu Ser Gln Phe Glu Phe Asn Phe Asn Tyr Leu Ala Arg Arg Trp Tyr 
145                 150                 155                 160 


Val Pro Val Lys Asp Leu Leu Gly Ile Tyr Glu Lys Leu Tyr Gly Arg 
                165                 170                 175     


Lys Val Ile Thr Glu Asn Val Ile Val Asp Cys Ser His Ile Gln Phe 
            180                 185                 190         


Leu Glu Met Tyr Gly Glu Met Leu Ala Val Ser Lys Leu Tyr Pro Thr 
        195                 200                 205             


Tyr Ser Thr Lys Ser Pro Phe Leu Val Glu Gln Phe Gln Glu Tyr Phe 
    210                 215                 220                 


Leu Gly Gly Leu Asp Asp Met Ala Phe Trp Ser Thr Asn Ile Tyr His 
225                 230                 235                 240 


Leu Thr Ser Phe Met Leu Glu Asn Gly Thr Ser Asp Cys Asn Leu Pro 
                245                 250                 255     


Glu Asn Pro Leu Phe Ile Ala Cys Gly Gly Gln Gln Asn His Thr Gln 
            260                 265                 270         


Gly Ser Lys Met Gln Lys Asn Asp Phe His Arg Asn Leu Thr Thr Ser 
        275                 280                 285             


Leu Thr Glu Ser Val Asp Arg Asn Ile Asn Tyr Thr Glu Arg Gly Val 
    290                 295                 300                 


Phe Phe Ser Val Asn Ser Trp Thr Pro Asp Ser Met Ser Phe Ile Tyr 
305                 310                 315                 320 


Lys Ala Leu Glu Arg Asn Ile Arg Thr Met Phe Ile Gly Gly Ser Gln 
                325                 330                 335     


Leu Ser Gln Lys His Val Ser Ser Pro Leu Ala Ser Tyr Phe Leu Ser 
            340                 345                 350         


Phe Pro Tyr Ala Arg Leu Gly Trp Ala Met Thr Ser Ala Asp Leu Asn 
        355                 360                 365             


Gln Asp Gly His Gly Asp Leu Val Val Gly Ala Pro Gly Tyr Ser Arg 
    370                 375                 380                 


Pro Gly His Ile His Ile Gly Arg Val Tyr Leu Ile Tyr Gly Asn Asp 
385                 390                 395                 400 


Leu Gly Leu Pro Pro Val Asp Leu Asp Leu Asp Lys Glu Ala His Arg 
                405                 410                 415     


Ile Leu Glu Gly Phe Gln Pro Ser Gly Arg Phe Gly Ser Ala Leu Ala 
            420                 425                 430         


Val Leu Asp Phe Asn Val Asp Gly Val Pro Asp Leu Ala Val Gly Ala 
        435                 440                 445             


Pro Ser Val Gly Ser Glu Gln Leu Thr Tyr Lys Gly Ala Val Tyr Val 
    450                 455                 460                 


Tyr Phe Gly Ser Lys Gln Gly Gly Met Ser Ser Ser Pro Asn Ile Thr 
465                 470                 475                 480 


Ile Ser Cys Gln Asp Ile Tyr Cys Asn Leu Gly Trp Thr Leu Leu Ala 
                485                 490                 495     


Ala Asp Val Asn Gly Asp Ser Glu Pro Asp Leu Val Ile Gly Ser Pro 
            500                 505                 510         


Phe Ala Pro Gly Gly Gly Lys Gln Lys Gly Ile Val Ala Ala Phe Tyr 
        515                 520                 525             


Ser Gly Pro Ser Leu Ser Asp Lys Glu Lys Leu Asn Val Glu Ala Ala 
    530                 535                 540                 


Asn Trp Thr Val Arg Gly Glu Glu Asp Phe Ser Trp Phe Gly Tyr Ser 
545                 550                 555                 560 


Leu His Gly Val Thr Val Asp Asn Arg Thr Leu Leu Leu Val Gly Ser 
                565                 570                 575     


Pro Thr Trp Lys Asn Ala Ser Arg Leu Gly His Leu Leu His Ile Arg 
            580                 585                 590         


Asp Glu Lys Lys Ser Leu Gly Arg Val Tyr Gly Tyr Phe Pro Pro Asn 
        595                 600                 605             


Gly Gln Ser Trp Phe Thr Ile Ser Gly Asp Lys Ala Met Gly Lys Leu 
    610                 615                 620                 


Gly Thr Ser Leu Ser Ser Gly His Val Leu Met Asn Gly Thr Leu Lys 
625                 630                 635                 640 


Gln Val Leu Leu Val Gly Ala Pro Thr Tyr Asp Asp Val Ser Lys Val 
                645                 650                 655     


Ala Phe Leu Thr Val Thr Leu His Gln Gly Gly Ala Thr Arg Met Tyr 
            660                 665                 670         


Ala Leu Thr Ser Asp Ala Gln Pro Leu Leu Leu Ser Thr Phe Ser Gly 
        675                 680                 685             


Asp Arg Arg Phe Ser Arg Phe Gly Gly Val Leu His Leu Ser Asp Leu 
    690                 695                 700                 


Asp Asp Asp Gly Leu Asp Glu Ile Ile Met Ala Ala Pro Leu Arg Ile 
705                 710                 715                 720 


Ala Asp Val Thr Ser Gly Leu Ile Gly Gly Glu Asp Gly Arg Val Tyr 
                725                 730                 735     


Val Tyr Asn Gly Lys Glu Thr Thr Leu Gly Asp Met Thr Gly Lys Cys 
            740                 745                 750         


Lys Ser Trp Ile Thr Pro Cys Pro Glu Glu Lys Ala Gln Tyr Val Leu 
        755                 760                 765             


Ile Ser Pro Glu Ala Ser Ser Arg Phe Gly Ser Ser Leu Ile Thr Val 
    770                 775                 780                 


Arg Ser Lys Ala Lys Asn Gln Val Val Ile Ala Ala Gly Arg Ser Ser 
785                 790                 795                 800 


Leu Gly Ala Arg Leu Ser Gly Ala Leu His Val Tyr Ser Leu Gly Ser 
                805                 810                 815     


Asp 
    


<210>  2337
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  2337

Gln Asp Ser Thr Ser Asp Leu Ile Pro Ala Pro Pro Leu Ser Lys Val 
1               5                   10                  15      


Pro Leu Gln Gln Asn Phe Gln Asp Asn Gln Phe Gln Gly Lys Trp Tyr 
            20                  25                  30          


Val Val Gly Leu Ala Gly Asn Ala Ile Leu Arg Glu Asp Lys Asp Pro 
        35                  40                  45              


Gln Lys Met Tyr Ala Thr Ile Tyr Glu Leu Lys Glu Asp Lys Ser Tyr 
    50                  55                  60                  


Asn Val Thr Ser Val Leu Phe Arg Lys Lys Lys Cys Asp Tyr Trp Ile 
65                  70                  75                  80  


Arg Thr Phe Val Pro Gly Cys Gln Pro Gly Glu Phe Thr Leu Gly Asn 
                85                  90                  95      


Ile Lys Ser Tyr Pro Gly Leu Thr Ser Tyr Leu Val Arg Val Val Ser 
            100                 105                 110         


Thr Asn Tyr Asn Gln His Ala Met Val Phe Phe Lys Lys Val Ser Gln 
        115                 120                 125             


Asn Arg Glu Tyr Phe Lys Ile Thr Leu Tyr Gly Arg Thr Lys Glu Leu 
    130                 135                 140                 


Thr Ser Glu Leu Lys Glu Asn Phe Ile Arg Phe Ser Lys Ser Leu Gly 
145                 150                 155                 160 


Leu Pro Glu Asn His Ile Val Phe Pro Val Pro Ile Asp Gln Cys Ile 
                165                 170                 175     


Asp Gly 
        


<210>  2338
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  2338

Glu Lys Leu His Thr Gln Pro Ser Cys Pro Ala Val Cys Gln Pro Thr 
1               5                   10                  15      


Arg Cys Pro Ala Leu Pro Thr Cys Ala Leu Gly Thr Thr Pro Val Phe 
            20                  25                  30          


Asp Leu Cys Arg Cys Cys Arg Val Cys Pro Ala Ala Glu Arg Glu Val 
        35                  40                  45              


Cys Gly Gly Ala Gln Gly Gln Pro Cys Ala Pro Gly Leu Gln Cys Leu 
    50                  55                  60                  


Gln Pro Leu Arg Pro Gly Phe Pro Ser Thr Cys Gly Cys Pro Thr Leu 
65                  70                  75                  80  


Gly Gly Ala Val Cys Gly Ser Asp Arg Arg Thr Tyr Pro Ser Met Cys 
                85                  90                  95      


Ala Leu Arg Ala Glu Asn Arg Ala Ala Arg Arg Leu Gly Lys Val Pro 
            100                 105                 110         


Ala Val Pro Val Gln Trp Gly Asn Cys Gly Asp Thr Gly Thr Arg Ser 
        115                 120                 125             


Ala Gly Pro Leu Arg Arg Asn Tyr Asn Phe Ile Ala Ala Val Val Glu 
    130                 135                 140                 


Lys Val Ala Pro Ser Val Val His Val Gln Leu Trp Gly Arg Leu Leu 
145                 150                 155                 160 


His Gly Ser Arg Leu Val Pro Val Tyr Ser Gly Ser Gly Phe Ile Val 
                165                 170                 175     


Ser Glu Asp Gly Leu Ile Ile Thr Asn Ala His Val Val Arg Asn Gln 
            180                 185                 190         


Gln Trp Ile Glu Val Val Leu Gln Asn Gly Ala Arg Tyr Glu Ala Val 
        195                 200                 205             


Val Lys Asp Ile Asp Leu Lys Leu Asp Leu Ala Val Ile Lys Ile Glu 
    210                 215                 220                 


Ser Asn Ala Glu Leu Pro Val Leu Met Leu Gly Arg Ser Ser Asp Leu 
225                 230                 235                 240 


Arg Ala Gly Glu Phe Val Val Ala Leu Gly Ser Pro Phe Ser Leu Gln 
                245                 250                 255     


Asn Thr Ala Thr Ala Gly Ile Val Ser Thr Lys Gln Arg Gly Gly Lys 
            260                 265                 270         


Glu Leu Gly Met Lys Asp Ser Asp Met Asp Tyr Val Gln Ile Asp Ala 
        275                 280                 285             


Thr Ile Asn Tyr Gly Asn Ser Gly Gly Pro Leu Val Asn Leu Asp Gly 
    290                 295                 300                 


Asp Val Ile Gly Val Asn Ser Leu Arg Val Thr Asp Gly Ile Ser Phe 
305                 310                 315                 320 


Ala Ile Pro Ser Asp Arg Val Arg Gln Phe Leu Ala Glu Tyr His Glu 
                325                 330                 335     


His Gln Met Lys Gly Lys Ala Phe Ser Asn Lys Lys Tyr Leu Gly Leu 
            340                 345                 350         


Gln Met Leu Ser Leu Thr Val Pro Leu Ser Glu Glu Leu Lys Met His 
        355                 360                 365             


Tyr Pro Asp Phe Pro Asp Val Ser Ser Gly Val Tyr Val Cys Lys Val 
    370                 375                 380                 


Phe Glu Gly Thr Ala Ala Gln Ser Ser Gly Leu Arg Asp His Asp Val 
385                 390                 395                 400 


Ile Val Asn Ile Asn Gly Lys Pro Ile Thr Thr Thr Thr Asp Val Val 
                405                 410                 415     


Lys Ala Leu Asp Ser Asp Ser Leu Ser Met Ala Val Leu Arg Gly Lys 
            420                 425                 430         


Asp Asn Leu Leu Leu Thr Val Ile Pro Glu Thr Ile Asn 
        435                 440                 445 


<210>  2339
<211>  436
<212>  PRT
<213>  Homo Sapiens

<400>  2339

Arg Glu Pro Pro Ala Ala Pro Cys Pro Ala Arg Cys Asp Val Ser Arg 
1               5                   10                  15      


Cys Pro Ser Pro Arg Cys Pro Gly Gly Tyr Val Pro Asp Leu Cys Asn 
            20                  25                  30          


Cys Cys Leu Val Cys Ala Ala Ser Glu Gly Glu Pro Cys Gly Gly Pro 
        35                  40                  45              


Leu Asp Ser Pro Cys Gly Glu Ser Leu Glu Cys Val Arg Gly Leu Cys 
    50                  55                  60                  


Arg Cys Arg Trp Ser His Ala Val Cys Gly Thr Asp Gly His Thr Tyr 
65                  70                  75                  80  


Ala Asn Val Cys Ala Leu Gln Ala Ala Ser Arg Arg Ala Leu Gln Leu 
                85                  90                  95      


Ser Gly Thr Pro Val Arg Gln Leu Gln Lys Gly Ala Cys Pro Leu Gly 
            100                 105                 110         


Leu His Gln Leu Ser Ser Pro Arg Tyr Lys Phe Asn Phe Ile Ala Asp 
        115                 120                 125             


Val Val Glu Lys Ile Ala Pro Ala Val Val His Ile Glu Leu Phe Leu 
    130                 135                 140                 


Arg His Pro Leu Phe Gly Arg Asn Val Pro Leu Ser Ser Gly Ser Gly 
145                 150                 155                 160 


Phe Ile Met Ser Glu Ala Gly Leu Ile Ile Thr Asn Ala His Val Val 
                165                 170                 175     


Ser Ser Asn Ser Ala Ala Pro Gly Arg Gln Gln Leu Lys Val Gln Leu 
            180                 185                 190         


Gln Asn Gly Asp Ser Tyr Glu Ala Thr Ile Lys Asp Ile Asp Lys Lys 
        195                 200                 205             


Ser Asp Ile Ala Thr Ile Lys Ile His Pro Lys Lys Lys Leu Pro Val 
    210                 215                 220                 


Leu Leu Leu Gly His Ser Ala Asp Leu Arg Pro Gly Glu Phe Val Val 
225                 230                 235                 240 


Ala Ile Gly Ser Pro Phe Ala Leu Gln Asn Thr Val Thr Thr Gly Ile 
                245                 250                 255     


Val Ser Thr Ala Gln Arg Glu Gly Arg Glu Leu Gly Leu Arg Asp Ser 
            260                 265                 270         


Asp Met Asp Tyr Ile Gln Thr Asp Ala Ile Ile Asn Tyr Gly Asn Ser 
        275                 280                 285             


Gly Gly Pro Leu Val Asn Leu Asp Gly Glu Val Ile Gly Ile Asn Thr 
    290                 295                 300                 


Leu Lys Val Thr Ala Gly Ile Ser Phe Ala Ile Pro Ser Asp Arg Ile 
305                 310                 315                 320 


Thr Arg Phe Leu Thr Glu Phe Gln Asp Lys Gln Ile Lys Asp Trp Lys 
                325                 330                 335     


Lys Arg Phe Ile Gly Ile Arg Met Arg Thr Ile Thr Pro Ser Leu Val 
            340                 345                 350         


Asp Glu Leu Lys Ala Ser Asn Pro Asp Phe Pro Glu Val Ser Ser Gly 
        355                 360                 365             


Ile Tyr Val Gln Glu Val Ala Pro Asn Ser Pro Ser Gln Arg Gly Gly 
    370                 375                 380                 


Ile Gln Asp Gly Asp Ile Ile Val Lys Val Asn Gly Arg Pro Leu Val 
385                 390                 395                 400 


Asp Ser Ser Glu Leu Gln Glu Ala Val Leu Thr Glu Ser Pro Leu Leu 
                405                 410                 415     


Leu Glu Val Arg Arg Gly Asn Asp Asp Leu Leu Phe Ser Ile Ala Pro 
            420                 425                 430         


Glu Val Val Met 
        435     


<210>  2340
<211>  260
<212>  PRT
<213>  Homo Sapiens

<400>  2340

Trp Gly Phe Lys Asp Gly Ile Phe His Asn Ser Ile Trp Leu Glu Arg 
1               5                   10                  15      


Ala Ala Gly Val Tyr His Arg Glu Ala Arg Ser Gly Lys Tyr Lys Leu 
            20                  25                  30          


Thr Tyr Ala Glu Ala Lys Ala Val Cys Glu Phe Glu Gly Gly His Leu 
        35                  40                  45              


Ala Thr Tyr Lys Gln Leu Glu Ala Ala Arg Lys Ile Gly Phe His Val 
    50                  55                  60                  


Cys Ala Ala Gly Trp Met Ala Lys Gly Arg Val Gly Tyr Pro Ile Val 
65                  70                  75                  80  


Lys Pro Gly Pro Asn Cys Gly Phe Gly Lys Thr Gly Ile Ile Asp Tyr 
                85                  90                  95      


Gly Ile Arg Leu Asn Arg Ser Glu Arg Trp Asp Ala Tyr Cys Tyr Asn 
            100                 105                 110         


Pro His Ala Lys Glu Cys Gly Gly Val Phe Thr Asp Pro Lys Gln Ile 
        115                 120                 125             


Phe Lys Ser Pro Gly Phe Pro Asn Glu Tyr Glu Asp Asn Gln Ile Cys 
    130                 135                 140                 


Tyr Trp His Ile Arg Leu Lys Tyr Gly Gln Arg Ile His Leu Ser Phe 
145                 150                 155                 160 


Leu Asp Phe Asp Leu Glu Asp Asp Pro Gly Cys Leu Ala Asp Tyr Val 
                165                 170                 175     


Glu Ile Tyr Asp Ser Tyr Asp Asp Val His Gly Phe Val Gly Arg Tyr 
            180                 185                 190         


Cys Gly Asp Glu Leu Pro Asp Asp Ile Ile Ser Thr Gly Asn Val Met 
        195                 200                 205             


Thr Leu Lys Phe Leu Ser Asp Ala Ser Val Thr Ala Gly Gly Phe Gln 
    210                 215                 220                 


Ile Lys Tyr Val Ala Met Asp Pro Val Ser Lys Ser Ser Gln Gly Lys 
225                 230                 235                 240 


Asn Thr Ser Thr Thr Ser Thr Gly Asn Lys Asn Phe Leu Ala Gly Arg 
                245                 250                 255     


Phe Ser His Leu 
            260 


<210>  2341
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  2341

Lys Thr Asp Ser Ser Phe Ile Met Asp Ser Asp Pro Arg Arg Cys Met 
1               5                   10                  15      


Arg His His Tyr Val Asp Ser Ile Ser His Pro Leu Tyr Lys Cys Ser 
            20                  25                  30          


Ser Lys Met Val Leu Leu Ala Arg Cys Glu Gly His Cys Ser Gln Ala 
        35                  40                  45              


Ser Arg Ser Glu Pro Leu Val Ser Phe Ser Thr Val Leu Lys Gln Pro 
    50                  55                  60                  


Phe Arg Ser Ser Cys His Cys Cys Arg Pro Gln Thr Ser Lys Leu Lys 
65                  70                  75                  80  


Ala Leu Arg Leu Arg Cys Ser Gly Gly Met Arg Leu Thr Ala Thr Tyr 
                85                  90                  95      


Arg Tyr Ile Leu Ser Cys His Cys Glu Glu Cys Asn Ser 
            100                 105                 


<210>  2342
<211>  347
<212>  PRT
<213>  Homo Sapiens

<400>  2342

Thr Asp Cys Pro Cys Pro Glu Pro Glu Leu Cys Arg Pro Ile Arg His 
1               5                   10                  15      


His Pro Asp Phe Glu Val Phe Val Phe Asp Val Gly Gln Lys Thr Trp 
            20                  25                  30          


Lys Ser Tyr Asp Trp Ser Gln Ile Thr Thr Val Ala Thr Phe Gly Lys 
        35                  40                  45              


Tyr Asp Ser Glu Leu Met Cys Tyr Ala His Ser Lys Gly Ala Arg Val 
    50                  55                  60                  


Val Leu Lys Gly Asp Val Ser Leu Lys Asp Ile Ile Asp Pro Ala Phe 
65                  70                  75                  80  


Arg Ala Ser Trp Ile Ala Gln Lys Leu Asn Leu Ala Lys Thr Gln Tyr 
                85                  90                  95      


Met Asp Gly Ile Asn Ile Asp Ile Glu Gln Glu Val Asn Cys Leu Ser 
            100                 105                 110         


Pro Glu Tyr Asp Ala Leu Thr Ala Leu Val Lys Glu Thr Thr Asp Ser 
        115                 120                 125             


Phe His Arg Glu Ile Glu Gly Ser Gln Val Thr Phe Asp Val Ala Trp 
    130                 135                 140                 


Ser Pro Lys Asn Ile Asp Arg Arg Cys Tyr Asn Tyr Thr Gly Ile Ala 
145                 150                 155                 160 


Asp Ala Cys Asp Phe Leu Phe Val Met Ser Tyr Asp Glu Gln Ser Gln 
                165                 170                 175     


Ile Trp Ser Glu Cys Ile Ala Ala Ala Asn Ala Pro Tyr Asn Gln Thr 
            180                 185                 190         


Leu Thr Gly Tyr Asn Asp Tyr Ile Lys Met Ser Ile Asn Pro Lys Lys 
        195                 200                 205             


Leu Val Met Gly Val Pro Trp Tyr Gly Tyr Asp Tyr Thr Cys Leu Asn 
    210                 215                 220                 


Leu Ser Glu Asp His Val Cys Thr Ile Ala Lys Val Pro Phe Arg Gly 
225                 230                 235                 240 


Ala Pro Cys Ser Asp Ala Ala Gly Arg Gln Val Pro Tyr Lys Thr Ile 
                245                 250                 255     


Met Lys Gln Ile Asn Ser Ser Ile Ser Gly Asn Leu Trp Asp Lys Asp 
            260                 265                 270         


Gln Arg Ala Pro Tyr Tyr Asn Tyr Lys Asp Pro Ala Gly His Phe His 
        275                 280                 285             


Gln Val Trp Tyr Asp Asn Pro Gln Ser Ile Ser Leu Lys Ala Thr Tyr 
    290                 295                 300                 


Ile Gln Asn Tyr Arg Leu Arg Gly Ile Gly Met Trp Asn Ala Asn Cys 
305                 310                 315                 320 


Leu Asp Tyr Ser Gly Asp Ala Val Ala Lys Gln Gln Thr Glu Glu Met 
                325                 330                 335     


Trp Glu Val Leu Lys Pro Lys Leu Leu Gln Arg 
            340                 345         


<210>  2343
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  2343

Glu Ser Leu Gln Glu Arg Ala Asp Glu Ala Thr Thr Gln Lys Gln Ser 
1               5                   10                  15      


Gly Glu Asp Asn Gln Asp Leu Ala Ile Ser Phe Ala Gly Asn Gly Leu 
            20                  25                  30          


Ser Ala Leu Arg Thr Ser Gly Ser Gln Ala Arg Ala Thr Cys Tyr Cys 
        35                  40                  45              


Arg Thr Gly Arg Cys Ala Thr Arg Glu Ser Leu Ser Gly Val Cys Glu 
    50                  55                  60                  


Ile Ser Gly Arg Leu Tyr Arg Leu Cys Cys Arg 
65                  70                  75  


<210>  2344
<211>  559
<212>  PRT
<213>  Homo Sapiens

<400>  2344

Gln Lys Gly Gly Ser Lys Gly Gln Leu Pro Ser Gly Ser Ser Gln Phe 
1               5                   10                  15      


Pro His Gly Lys Lys Gly Gln His Tyr Phe Gly Gln Lys Asp Gln Gln 
            20                  25                  30          


His Thr Lys Ser Lys Gly Ser Phe Ser Ile Gln His Thr Tyr His Val 
        35                  40                  45              


Asp Ile Asn Asp His Asp Trp Thr Arg Lys Ser Gln Gln Tyr Asp Leu 
    50                  55                  60                  


Asn Ala Leu His Lys Ala Thr Lys Ser Lys Gln His Leu Gly Gly Ser 
65                  70                  75                  80  


Gln Gln Leu Leu Asn Tyr Lys Gln Glu Gly Arg Asp His Asp Lys Ser 
                85                  90                  95      


Lys Gly His Phe His Met Ile Val Ile His His Lys Gly Gly Gln Ala 
            100                 105                 110         


His His Gly Thr Gln Asn Pro Ser Gln Asp Gln Gly Asn Ser Pro Ser 
        115                 120                 125             


Gly Lys Gly Leu Ser Ser Gln Cys Ser Asn Thr Glu Lys Arg Leu Trp 
    130                 135                 140                 


Val His Gly Leu Ser Lys Glu Gln Ala Ser Ala Ser Gly Ala Gln Lys 
145                 150                 155                 160 


Gly Arg Thr Gln Gly Gly Ser Gln Ser Ser Tyr Val Leu Gln Thr Glu 
                165                 170                 175     


Glu Leu Val Val Asn Lys Gln Gln Arg Glu Thr Lys Asn Ser His Gln 
            180                 185                 190         


Asn Lys Gly His Tyr Gln Asn Val Val Asp Val Arg Glu Glu His Ser 
        195                 200                 205             


Ser Lys Leu Gln Thr Ser Leu His Pro Ala His Gln Asp Arg Leu Gln 
    210                 215                 220                 


His Gly Pro Lys Asp Ile Phe Thr Thr Gln Asp Glu Leu Leu Val Tyr 
225                 230                 235                 240 


Asn Lys Asn Gln His Gln Thr Lys Asn Leu Asn Gln Asp Gln Glu His 
                245                 250                 255     


Gly Arg Lys Ala His Lys Ile Ser Tyr Pro Ser Ser Arg Thr Glu Glu 
            260                 265                 270         


Arg Gln Leu His His Gly Glu Lys Ser Val Gln Lys Asp Val Ser Lys 
        275                 280                 285             


Gly Ser Ile Ser Ile Gln Thr Glu Glu Lys Ile His Gly Lys Ser Gln 
    290                 295                 300                 


Asn Gln Val Thr Ile His Ser Gln Asp Gln Glu His Gly His Lys Glu 
305                 310                 315                 320 


Asn Lys Ile Ser Tyr Gln Ser Ser Ser Thr Glu Glu Arg His Leu Asn 
                325                 330                 335     


Cys Gly Glu Lys Gly Ile Gln Lys Gly Val Ser Lys Gly Ser Ile Ser 
            340                 345                 350         


Ile Gln Thr Glu Glu Gln Ile His Gly Lys Ser Gln Asn Gln Val Arg 
        355                 360                 365             


Ile Pro Ser Gln Ala Gln Glu Tyr Gly His Lys Glu Asn Lys Ile Ser 
    370                 375                 380                 


Tyr Gln Ser Ser Ser Thr Glu Glu Arg Arg Leu Asn Ser Gly Glu Lys 
385                 390                 395                 400 


Asp Val Gln Lys Gly Val Ser Lys Gly Ser Ile Ser Ile Gln Thr Glu 
                405                 410                 415     


Glu Lys Ile His Gly Lys Ser Gln Asn Gln Val Thr Ile Pro Ser Gln 
            420                 425                 430         


Asp Gln Glu His Gly His Lys Glu Asn Lys Met Ser Tyr Gln Ser Ser 
        435                 440                 445             


Ser Thr Glu Glu Arg Arg Leu Asn Tyr Gly Gly Lys Ser Thr Gln Lys 
    450                 455                 460                 


Asp Val Ser Gln Ser Ser Ile Ser Phe Gln Ile Glu Lys Leu Val Glu 
465                 470                 475                 480 


Gly Lys Ser Gln Ile Gln Thr Pro Asn Pro Asn Gln Asp Gln Trp Ser 
                485                 490                 495     


Gly Gln Asn Ala Lys Gly Lys Ser Gly Gln Ser Ala Asp Ser Lys Gln 
            500                 505                 510         


Asp Leu Leu Ser His Glu Gln Lys Gly Arg Tyr Lys Gln Glu Ser Ser 
        515                 520                 525             


Glu Ser His Asn Ile Val Ile Thr Glu His Glu Val Ala Gln Asp Asp 
    530                 535                 540                 


His Leu Thr Gln Gln Tyr Asn Glu Asp Arg Asn Pro Ile Ser Thr 
545                 550                 555                 


<210>  2345
<211>  499
<212>  PRT
<213>  Homo Sapiens

<400>  2345

Glu Trp Ile Lys Phe Ala Ala Ala Cys Arg Glu Gly Glu Asp Asn Ser 
1               5                   10                  15      


Lys Arg Asn Pro Ile Ala Lys Ile His Ser Asp Cys Ala Ala Asn Gln 
            20                  25                  30          


Gln Val Thr Tyr Arg Ile Ser Gly Val Gly Ile Asp Gln Pro Pro Tyr 
        35                  40                  45              


Gly Ile Phe Val Ile Asn Gln Lys Thr Gly Glu Ile Asn Ile Thr Ser 
    50                  55                  60                  


Ile Val Asp Arg Glu Val Thr Pro Phe Phe Ile Ile Tyr Cys Arg Ala 
65                  70                  75                  80  


Leu Asn Ser Met Gly Gln Asp Leu Glu Arg Pro Leu Glu Leu Arg Val 
                85                  90                  95      


Arg Val Leu Asp Ile Asn Asp Asn Pro Pro Val Phe Ser Met Ala Thr 
            100                 105                 110         


Phe Ala Gly Gln Ile Glu Glu Asn Ser Asn Ala Asn Thr Leu Val Met 
        115                 120                 125             


Ile Leu Asn Ala Thr Asp Ala Asp Glu Pro Asn Asn Leu Asn Ser Lys 
    130                 135                 140                 


Ile Ala Phe Lys Ile Ile Arg Gln Glu Pro Ser Asp Ser Pro Met Phe 
145                 150                 155                 160 


Ile Ile Asn Arg Asn Thr Gly Glu Ile Arg Thr Met Asn Asn Phe Leu 
                165                 170                 175     


Asp Arg Glu Gln Tyr Gly Gln Tyr Ala Leu Ala Val Arg Gly Ser Asp 
            180                 185                 190         


Arg Asp Gly Gly Ala Asp Gly Met Ser Ala Glu Cys Glu Cys Asn Ile 
        195                 200                 205             


Lys Ile Leu Asp Val Asn Asp Asn Ile Pro Tyr Met Glu Gln Ser Ser 
    210                 215                 220                 


Tyr Thr Ile Glu Ile Gln Glu Asn Thr Leu Asn Ser Asn Leu Leu Glu 
225                 230                 235                 240 


Ile Arg Val Ile Asp Leu Asp Glu Glu Phe Ser Ala Asn Trp Met Ala 
                245                 250                 255     


Val Ile Phe Phe Ile Ser Gly Asn Glu Gly Asn Trp Phe Glu Ile Glu 
            260                 265                 270         


Met Asn Glu Arg Thr Asn Val Gly Ile Leu Lys Val Val Lys Pro Leu 
        275                 280                 285             


Asp Tyr Glu Ala Met Gln Ser Leu Gln Leu Ser Ile Gly Val Arg Asn 
    290                 295                 300                 


Lys Ala Glu Phe His His Ser Ile Met Ser Gln Tyr Lys Leu Lys Ala 
305                 310                 315                 320 


Ser Ala Ile Ser Val Thr Val Leu Asn Val Ile Glu Gly Pro Val Phe 
                325                 330                 335     


Arg Pro Gly Ser Lys Thr Tyr Val Val Thr Gly Asn Met Gly Ser Asn 
            340                 345                 350         


Asp Lys Val Gly Asp Phe Val Ala Thr Asp Leu Asp Thr Gly Arg Pro 
        355                 360                 365             


Ser Thr Thr Val Arg Tyr Val Met Gly Asn Asn Pro Ala Asp Leu Leu 
    370                 375                 380                 


Ala Val Asp Ser Arg Thr Gly Lys Leu Thr Leu Lys Asn Lys Val Thr 
385                 390                 395                 400 


Lys Glu Gln Tyr Asn Met Leu Gly Gly Lys Tyr Gln Gly Thr Ile Leu 
                405                 410                 415     


Ser Ile Asp Asp Asn Leu Gln Arg Thr Cys Thr Gly Thr Ile Asn Ile 
            420                 425                 430         


Asn Ile Gln Ser Phe Gly Asn Asp Asp Arg Thr Asn Thr Glu Pro Asn 
        435                 440                 445             


Thr Lys Ile Thr Thr Asn Thr Gly Arg Gln Glu Ser Thr Ser Ser Thr 
    450                 455                 460                 


Asn Tyr Asp Thr Ser Thr Thr Ser Thr Asp Ser Ser Gln Val Tyr Ser 
465                 470                 475                 480 


Ser Glu Pro Gly Asn Gly Ala Lys Asp Leu Leu Ser Asp Asn Val His 
                485                 490                 495     


Phe Gly Pro 
            


<210>  2346
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2346

Val Thr Val Gln Asp Gly Asn Phe Ser Phe Ser Leu Glu Ser Val Lys 
1               5                   10                  15      


Lys Leu Lys Asp Leu Gln Glu Pro Gln Glu Pro Arg Val Gly Lys Leu 
            20                  25                  30          


Arg Asn Phe Ala Pro Ile Pro Gly Glu Pro Val Val Pro Ile Leu Cys 
        35                  40                  45              


Ser Asn Pro Asn Phe Pro Glu Glu Leu Lys Pro Leu Cys Lys Glu Pro 
    50                  55                  60                  


Asn Ala Gln Glu Ile Leu Gln Arg Leu Glu Glu Ile Ala Glu Asp Pro 
65                  70                  75                  80  


Gly Thr Cys Glu Ile Cys Ala Tyr Ala Ala Cys Thr Gly Cys 
                85                  90                  


<210>  2347
<211>  709
<212>  PRT
<213>  Homo Sapiens

<400>  2347

Lys Gly Asp Ala Lys Pro Glu Asp Asn Leu Leu Val Leu Thr Val Ala 
1               5                   10                  15      


Thr Lys Glu Thr Glu Gly Phe Arg Arg Phe Lys Arg Ser Ala Gln Phe 
            20                  25                  30          


Phe Asn Tyr Lys Ile Gln Ala Leu Gly Leu Gly Glu Asp Trp Asn Val 
        35                  40                  45              


Glu Lys Gly Thr Ser Ala Gly Gly Gly Gln Lys Val Arg Leu Leu Lys 
    50                  55                  60                  


Lys Ala Leu Glu Lys His Ala Asp Lys Glu Asp Leu Val Ile Leu Phe 
65                  70                  75                  80  


Thr Asp Ser Tyr Asp Val Leu Phe Ala Ser Gly Pro Arg Glu Leu Leu 
                85                  90                  95      


Lys Lys Phe Arg Gln Ser Arg Ser Gln Val Val Phe Ser Ala Glu Glu 
            100                 105                 110         


Leu Ile Tyr Pro Asp Arg Arg Leu Glu Thr Lys Tyr Pro Val Val Ser 
        115                 120                 125             


Asp Gly Lys Arg Phe Leu Gly Ser Gly Gly Phe Ile Gly Tyr Ala Pro 
    130                 135                 140                 


Asn Leu Ser Lys Leu Val Ala Glu Trp Glu Gly Gln Asp Ser Asp Ser 
145                 150                 155                 160 


Asp Gln Leu Phe Tyr Thr Lys Ile Phe Leu Asp Pro Glu Lys Arg Glu 
                165                 170                 175     


Gln Ile Asn Ile Thr Leu Asp His Arg Cys Arg Ile Phe Gln Asn Leu 
            180                 185                 190         


Asp Gly Ala Leu Asp Glu Val Val Leu Lys Phe Glu Met Gly His Val 
        195                 200                 205             


Arg Ala Arg Asn Leu Ala Tyr Asp Thr Leu Pro Val Leu Ile His Gly 
    210                 215                 220                 


Asn Gly Pro Thr Lys Leu Gln Leu Asn Tyr Leu Gly Asn Tyr Ile Pro 
225                 230                 235                 240 


Arg Phe Trp Thr Phe Glu Thr Gly Cys Thr Val Cys Asp Glu Gly Leu 
                245                 250                 255     


Arg Ser Leu Lys Gly Ile Gly Asp Glu Ala Leu Pro Thr Val Leu Val 
            260                 265                 270         


Gly Val Phe Ile Glu Gln Pro Thr Pro Phe Val Ser Leu Phe Phe Gln 
        275                 280                 285             


Arg Leu Leu Arg Leu His Tyr Pro Gln Lys His Met Arg Leu Phe Ile 
    290                 295                 300                 


His Asn His Glu Gln His His Lys Ala Gln Val Glu Glu Phe Leu Ala 
305                 310                 315                 320 


Gln His Gly Ser Glu Tyr Gln Ser Val Lys Leu Val Gly Pro Glu Val 
                325                 330                 335     


Arg Met Ala Asn Ala Asp Ala Arg Asn Met Gly Ala Asp Leu Cys Arg 
            340                 345                 350         


Gln Asp Arg Ser Cys Thr Tyr Tyr Phe Ser Val Asp Ala Asp Val Ala 
        355                 360                 365             


Leu Thr Glu Pro Asn Ser Leu Arg Leu Leu Ile Gln Gln Asn Lys Asn 
    370                 375                 380                 


Val Ile Ala Pro Leu Met Thr Arg His Gly Arg Leu Trp Ser Asn Phe 
385                 390                 395                 400 


Trp Gly Ala Leu Ser Ala Asp Gly Tyr Tyr Ala Arg Ser Glu Asp Tyr 
                405                 410                 415     


Val Asp Ile Val Gln Gly Arg Arg Val Gly Val Trp Asn Val Pro Tyr 
            420                 425                 430         


Ile Ser Asn Ile Tyr Leu Ile Lys Gly Ser Ala Leu Arg Gly Glu Leu 
        435                 440                 445             


Gln Ser Ser Asp Leu Phe His His Ser Lys Leu Asp Pro Asp Met Ala 
    450                 455                 460                 


Phe Cys Ala Asn Ile Arg Gln Gln Asp Val Phe Met Phe Leu Thr Asn 
465                 470                 475                 480 


Arg His Thr Leu Gly His Leu Leu Ser Leu Asp Ser Tyr Arg Thr Thr 
                485                 490                 495     


His Leu His Asn Asp Leu Trp Glu Val Phe Ser Asn Pro Glu Asp Trp 
            500                 505                 510         


Lys Glu Lys Tyr Ile His Gln Asn Tyr Thr Lys Ala Leu Ala Gly Lys 
        515                 520                 525             


Leu Val Glu Thr Pro Cys Pro Asp Val Tyr Trp Phe Pro Ile Phe Thr 
    530                 535                 540                 


Glu Val Ala Cys Asp Glu Leu Val Glu Glu Met Glu His Phe Gly Gln 
545                 550                 555                 560 


Trp Ser Leu Gly Asn Asn Lys Asp Asn Arg Ile Gln Gly Gly Tyr Glu 
                565                 570                 575     


Asn Val Pro Thr Ile Asp Ile His Met Asn Gln Ile Gly Phe Glu Arg 
            580                 585                 590         


Glu Trp His Lys Phe Leu Leu Glu Tyr Ile Ala Pro Met Thr Glu Lys 
        595                 600                 605             


Leu Tyr Pro Gly Tyr Tyr Thr Arg Ala Gln Phe Asp Leu Ala Phe Val 
    610                 615                 620                 


Val Arg Tyr Lys Pro Asp Glu Gln Pro Ser Leu Met Pro His His Asp 
625                 630                 635                 640 


Ala Ser Thr Phe Thr Ile Asn Ile Ala Leu Asn Arg Val Gly Val Asp 
                645                 650                 655     


Tyr Glu Gly Gly Gly Cys Arg Phe Leu Arg Tyr Asn Cys Ser Ile Arg 
            660                 665                 670         


Ala Pro Arg Lys Gly Trp Thr Leu Met His Pro Gly Arg Leu Thr His 
        675                 680                 685             


Tyr His Glu Gly Leu Pro Thr Thr Arg Gly Thr Arg Tyr Ile Ala Val 
    690                 695                 700                 


Ser Phe Val Asp Pro 
705                 


<210>  2348
<211>  411
<212>  PRT
<213>  Homo Sapiens

<400>  2348

Ala Val Phe Thr Val Gly Val Leu Gly Pro Trp Ala Cys Asp Pro Ile 
1               5                   10                  15      


Phe Ser Arg Ala Arg Pro Asp Leu Ala Ala Arg Leu Ala Ala Ala Arg 
            20                  25                  30          


Leu Asn Arg Asp Pro Gly Leu Ala Gly Gly Pro Arg Phe Glu Val Ala 
        35                  40                  45              


Leu Leu Pro Glu Pro Cys Arg Thr Pro Gly Ser Leu Gly Ala Val Ser 
    50                  55                  60                  


Ser Ala Leu Ala Arg Val Ser Gly Leu Val Gly Pro Val Asn Pro Ala 
65                  70                  75                  80  


Ala Cys Arg Pro Ala Glu Leu Leu Ala Glu Glu Ala Gly Ile Ala Leu 
                85                  90                  95      


Val Pro Trp Gly Cys Pro Trp Thr Gln Ala Glu Gly Thr Thr Ala Pro 
            100                 105                 110         


Ala Val Thr Pro Ala Ala Asp Ala Leu Tyr Ala Leu Leu Arg Ala Phe 
        115                 120                 125             


Gly Trp Ala Arg Val Ala Leu Val Thr Ala Pro Gln Asp Leu Trp Val 
    130                 135                 140                 


Glu Ala Gly Arg Ser Leu Ser Thr Ala Leu Arg Ala Arg Gly Leu Pro 
145                 150                 155                 160 


Val Ala Ser Val Thr Ser Met Glu Pro Leu Asp Leu Ser Gly Ala Arg 
                165                 170                 175     


Glu Ala Leu Arg Lys Val Arg Asp Gly Pro Arg Val Thr Ala Val Ile 
            180                 185                 190         


Met Val Met His Ser Val Leu Leu Gly Gly Glu Glu Gln Arg Tyr Leu 
        195                 200                 205             


Leu Glu Ala Ala Glu Glu Leu Gly Leu Thr Asp Gly Ser Leu Val Phe 
    210                 215                 220                 


Leu Pro Phe Asp Thr Ile His Tyr Ala Leu Ser Pro Gly Pro Glu Ala 
225                 230                 235                 240 


Leu Ala Ala Leu Ala Asn Ser Ser Gln Leu Arg Arg Ala His Asp Ala 
                245                 250                 255     


Val Leu Thr Leu Thr Arg His Cys Pro Ser Glu Gly Ser Val Leu Asp 
            260                 265                 270         


Ser Leu Arg Arg Ala Gln Glu Arg Arg Glu Leu Pro Ser Asp Leu Asn 
        275                 280                 285             


Leu Gln Gln Val Ser Pro Leu Phe Gly Thr Ile Tyr Asp Ala Val Phe 
    290                 295                 300                 


Leu Leu Ala Arg Gly Val Ala Glu Ala Arg Ala Ala Ala Gly Gly Arg 
305                 310                 315                 320 


Trp Val Ser Gly Ala Ala Val Ala Arg His Ile Arg Asp Ala Gln Val 
                325                 330                 335     


Pro Gly Phe Cys Gly Asp Leu Gly Gly Asp Glu Glu Pro Pro Phe Val 
            340                 345                 350         


Leu Leu Asp Thr Asp Ala Ala Gly Asp Arg Leu Phe Ala Thr Tyr Met 
        355                 360                 365             


Leu Asp Pro Ala Arg Gly Ser Phe Leu Ser Ala Gly Thr Arg Met His 
    370                 375                 380                 


Phe Pro Arg Gly Gly Ser Ala Pro Gly Pro Asp Pro Ser Cys Trp Phe 
385                 390                 395                 400 


Asp Pro Asn Asn Ile Cys Gly Gly Gly Leu Glu 
                405                 410     


<210>  2349
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  2349

Gln Val Lys Pro Cys Asp Phe Pro Asp Ile Lys His Gly Gly Leu Phe 
1               5                   10                  15      


His Glu Asn Met Arg Arg Pro Tyr Phe Pro Val Ala Val Gly Lys Tyr 
            20                  25                  30          


Tyr Ser Tyr Tyr Cys Asp Glu His Phe Glu Thr Pro Ser Gly Ser Tyr 
        35                  40                  45              


Trp Asp Tyr Ile His Cys Thr Gln Asn Gly Trp Ser Pro Ala Val Pro 
    50                  55                  60                  


Cys Leu Arg Lys Cys Tyr Phe Pro Tyr Leu Glu Asn Gly Tyr Asn Gln 
65                  70                  75                  80  


Asn Tyr Gly Arg Lys Phe Val Gln Gly Asn Ser Thr Glu Val Ala Cys 
                85                  90                  95      


His Pro Gly Tyr Gly Leu Pro Lys Ala Gln Thr Thr Val Thr Cys Thr 
            100                 105                 110         


Glu Lys Gly Trp Ser Pro Thr Pro Arg Cys Ile Arg Val Arg Thr Cys 
        115                 120                 125             


Ser Lys Ser Asp Ile Glu Ile Glu Asn Gly Phe Ile Ser Glu Ser Ser 
    130                 135                 140                 


Ser Ile Tyr Ile Leu Asn Lys Glu Ile Gln Tyr Lys Cys Lys Pro Gly 
145                 150                 155                 160 


Tyr Ala Thr Ala Asp Gly Asn Ser Ser Gly Ser Ile Thr Cys Leu Gln 
                165                 170                 175     


Asn Gly Trp Ser Ala Gln Pro Ile Cys Ile Asn Ser Ser Glu Lys Cys 
            180                 185                 190         


Gly Pro Pro Pro Pro Ile Ser Asn Gly Asp Thr Thr Ser Phe Leu Leu 
        195                 200                 205             


Lys Val Tyr Val Pro Gln Ser Arg Val Glu Tyr Gln Cys Gln Pro Tyr 
    210                 215                 220                 


Tyr Glu Leu Gln Gly Ser Asn Tyr Val Thr Cys Ser Asn Gly Glu Trp 
225                 230                 235                 240 


Ser Glu Pro Pro Arg Cys Ile His Pro Cys Ile Ile Thr Glu Glu Asn 
                245                 250                 255     


Met Asn Lys Asn Asn Ile Lys Leu Lys Gly Arg Ser Asp Arg Lys Tyr 
            260                 265                 270         


Tyr Ala Lys Thr Gly Asp Thr Ile Glu Phe Met Cys Lys Leu Gly Tyr 
        275                 280                 285             


Asn Ala Asn Thr Ser Ile Leu Ser Phe Gln Ala Val Cys Arg Glu Gly 
    290                 295                 300                 


Ile Val Glu Tyr Pro Arg Cys Glu 
305                 310         


<210>  2350
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  2350

Glu Lys Pro Ser Pro Cys Gln Cys Ser Arg Leu Ser Pro His Asn Arg 
1               5                   10                  15      


Thr Asn Cys Gly Phe Pro Gly Ile Thr Ser Asp Gln Cys Phe Asp Asn 
            20                  25                  30          


Gly Cys Cys Phe Asp Ser Ser Val Thr Gly Val Pro Trp Cys Phe His 
        35                  40                  45              


Pro Leu Pro Lys Gln Glu Ser Asp Gln Cys Val Met Glu Val Ser Asp 
    50                  55                  60                  


Arg Arg Asn Cys Gly Tyr Pro Gly Ile Ser Pro Glu Glu Cys Ala Ser 
65                  70                  75                  80  


Arg Lys Cys Cys Phe Ser Asn Phe Ile Phe Glu Val Pro Trp Cys Phe 
                85                  90                  95      


Phe Pro Lys Ser Val Glu Asp Cys His Tyr 
            100                 105     


<210>  2351
<211>  312
<212>  PRT
<213>  Homo Sapiens

<400>  2351

Glu Ala Thr Phe Cys Asp Phe Pro Lys Ile Asn His Gly Ile Leu Tyr 
1               5                   10                  15      


Asp Glu Glu Lys Tyr Lys Pro Phe Ser Gln Val Pro Thr Gly Glu Val 
            20                  25                  30          


Phe Tyr Tyr Ser Cys Glu Tyr Asn Phe Val Ser Pro Ser Lys Ser Phe 
        35                  40                  45              


Trp Thr Arg Ile Thr Cys Thr Glu Glu Gly Trp Ser Pro Thr Pro Lys 
    50                  55                  60                  


Cys Leu Arg Leu Cys Phe Phe Pro Phe Val Glu Asn Gly His Ser Glu 
65                  70                  75                  80  


Ser Ser Gly Gln Thr His Leu Glu Gly Asp Thr Val Gln Ile Ile Cys 
                85                  90                  95      


Asn Thr Gly Tyr Arg Leu Gln Asn Asn Glu Asn Asn Ile Ser Cys Val 
            100                 105                 110         


Glu Arg Gly Trp Ser Thr Pro Pro Lys Cys Arg Ser Thr Asp Thr Ser 
        115                 120                 125             


Cys Val Asn Pro Pro Thr Val Gln Asn Ala His Ile Leu Ser Arg Gln 
    130                 135                 140                 


Met Ser Lys Tyr Pro Ser Gly Glu Arg Val Arg Tyr Glu Cys Arg Ser 
145                 150                 155                 160 


Pro Tyr Glu Met Phe Gly Asp Glu Glu Val Met Cys Leu Asn Gly Asn 
                165                 170                 175     


Trp Thr Glu Pro Pro Gln Cys Lys Asp Ser Thr Gly Lys Cys Gly Pro 
            180                 185                 190         


Pro Pro Pro Ile Asp Asn Gly Asp Ile Thr Ser Phe Pro Leu Ser Val 
        195                 200                 205             


Tyr Ala Pro Ala Ser Ser Val Glu Tyr Gln Cys Gln Asn Leu Tyr Gln 
    210                 215                 220                 


Leu Glu Gly Asn Lys Arg Ile Thr Cys Arg Asn Gly Gln Trp Ser Glu 
225                 230                 235                 240 


Pro Pro Lys Cys Leu His Pro Cys Val Ile Ser Arg Glu Ile Met Glu 
                245                 250                 255     


Asn Tyr Asn Ile Ala Leu Arg Trp Thr Ala Lys Gln Lys Leu Tyr Leu 
            260                 265                 270         


Arg Thr Gly Glu Ser Ala Glu Phe Val Cys Lys Arg Gly Tyr Arg Leu 
        275                 280                 285             


Ser Ser Arg Ser His Thr Leu Arg Thr Thr Cys Trp Asp Gly Lys Leu 
    290                 295                 300                 


Glu Tyr Pro Thr Cys Ala Lys Arg 
305                 310         


<210>  2352
<211>  662
<212>  PRT
<213>  Homo Sapiens

<400>  2352

Val Phe Tyr Ala Glu Arg Tyr Gln Met Pro Thr Gly Ile Lys Gly Pro 
1               5                   10                  15      


Leu Pro Asn Thr Lys Thr Gln Phe Phe Ile Pro Tyr Thr Ile Lys Ser 
            20                  25                  30          


Lys Gly Ile Ala Val Arg Gly Glu Gln Gly Thr Pro Gly Pro Pro Gly 
        35                  40                  45              


Pro Ala Gly Pro Arg Gly His Pro Gly Pro Ser Gly Pro Pro Gly Lys 
    50                  55                  60                  


Pro Gly Tyr Gly Ser Pro Gly Leu Gln Gly Glu Pro Gly Leu Pro Gly 
65                  70                  75                  80  


Pro Pro Gly Pro Ser Ala Val Gly Lys Pro Gly Val Pro Gly Leu Pro 
                85                  90                  95      


Gly Lys Pro Gly Glu Arg Gly Pro Tyr Gly Pro Lys Gly Asp Val Gly 
            100                 105                 110         


Pro Ala Gly Leu Pro Gly Pro Arg Gly Pro Pro Gly Pro Pro Gly Ile 
        115                 120                 125             


Pro Gly Pro Ala Gly Ile Ser Val Pro Gly Lys Pro Gly Gln Gln Gly 
    130                 135                 140                 


Pro Thr Gly Ala Pro Gly Pro Arg Gly Phe Pro Gly Glu Lys Gly Ala 
145                 150                 155                 160 


Pro Gly Val Pro Gly Met Asn Gly Gln Lys Gly Glu Met Gly Tyr Gly 
                165                 170                 175     


Ala Pro Gly Arg Pro Gly Glu Arg Gly Leu Pro Gly Pro Gln Gly Pro 
            180                 185                 190         


Thr Gly Pro Ser Gly Pro Pro Gly Val Gly Lys Arg Gly Glu Asn Gly 
        195                 200                 205             


Val Pro Gly Gln Pro Gly Ile Lys Gly Asp Arg Gly Phe Pro Gly Glu 
    210                 215                 220                 


Met Gly Pro Ile Gly Pro Pro Gly Pro Gln Gly Pro Pro Gly Glu Arg 
225                 230                 235                 240 


Gly Pro Glu Gly Ile Gly Lys Pro Gly Ala Ala Gly Ala Pro Gly Gln 
                245                 250                 255     


Pro Gly Ile Pro Gly Thr Lys Gly Leu Pro Gly Ala Pro Gly Ile Ala 
            260                 265                 270         


Gly Pro Pro Gly Pro Pro Gly Phe Gly Lys Pro Gly Leu Pro Gly Leu 
        275                 280                 285             


Lys Gly Glu Arg Gly Pro Ala Gly Leu Pro Gly Gly Pro Gly Ala Lys 
    290                 295                 300                 


Gly Glu Gln Gly Pro Ala Gly Leu Pro Gly Lys Pro Gly Leu Thr Gly 
305                 310                 315                 320 


Pro Pro Gly Asn Met Gly Pro Gln Gly Pro Lys Gly Ile Pro Gly Ser 
                325                 330                 335     


His Gly Leu Pro Gly Pro Lys Gly Glu Thr Gly Pro Ala Gly Pro Ala 
            340                 345                 350         


Gly Tyr Pro Gly Ala Lys Gly Glu Arg Gly Ser Pro Gly Ser Asp Gly 
        355                 360                 365             


Lys Pro Gly Tyr Pro Gly Lys Pro Gly Leu Asp Gly Pro Lys Gly Asn 
    370                 375                 380                 


Pro Gly Leu Pro Gly Pro Lys Gly Asp Pro Gly Val Gly Gly Pro Pro 
385                 390                 395                 400 


Gly Leu Pro Gly Pro Val Gly Pro Ala Gly Ala Lys Gly Met Pro Gly 
                405                 410                 415     


His Asn Gly Glu Ala Gly Pro Arg Gly Ala Pro Gly Ile Pro Gly Thr 
            420                 425                 430         


Arg Gly Pro Ile Gly Pro Pro Gly Ile Pro Gly Phe Pro Gly Ser Lys 
        435                 440                 445             


Gly Asp Pro Gly Ser Pro Gly Pro Pro Gly Pro Ala Gly Ile Ala Thr 
    450                 455                 460                 


Lys Gly Leu Asn Gly Pro Thr Gly Pro Pro Gly Pro Pro Gly Pro Arg 
465                 470                 475                 480 


Gly His Ser Gly Glu Pro Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly 
                485                 490                 495     


Pro Pro Gly Gln Ala Val Met Pro Glu Gly Phe Ile Lys Ala Gly Gln 
            500                 505                 510         


Arg Pro Ser Leu Ser Gly Thr Pro Leu Val Ser Ala Asn Gln Gly Val 
        515                 520                 525             


Thr Gly Met Pro Val Ser Ala Phe Thr Val Ile Leu Ser Lys Ala Tyr 
    530                 535                 540                 


Pro Ala Ile Gly Thr Pro Ile Pro Phe Asp Lys Ile Leu Tyr Asn Arg 
545                 550                 555                 560 


Gln Gln His Tyr Asp Pro Arg Thr Gly Ile Phe Thr Cys Gln Ile Pro 
                565                 570                 575     


Gly Ile Tyr Tyr Phe Ser Tyr His Val His Val Lys Gly Thr His Val 
            580                 585                 590         


Trp Val Gly Leu Tyr Lys Asn Gly Thr Pro Val Met Tyr Thr Tyr Asp 
        595                 600                 605             


Glu Tyr Thr Lys Gly Tyr Leu Asp Gln Ala Ser Gly Ser Ala Ile Ile 
    610                 615                 620                 


Asp Leu Thr Glu Asn Asp Gln Val Trp Leu Gln Leu Pro Asn Ala Glu 
625                 630                 635                 640 


Ser Asn Gly Leu Tyr Ser Ser Glu Tyr Val His Ser Ser Phe Ser Gly 
                645                 650                 655     


Phe Leu Val Ala Pro Met 
            660         


<210>  2353
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2353

Met Glu Asp Glu Lys Pro Lys Val Asn Pro Lys Leu Tyr Met Cys Val 
1               5                   10                  15      


Cys Glu Gly Leu Ser Cys Gly Asn Glu Asp His Cys Glu Gly Gln Gln 
            20                  25                  30          


Cys Phe Ser Ser Leu Ser Ile Asn Asp Gly Phe His Val Tyr Gln Lys 
        35                  40                  45              


Gly Cys Phe Gln Val Tyr Glu Gln Gly Lys Met Thr Cys Lys Thr Pro 
    50                  55                  60                  


Pro Ser Pro Gly Gln Ala Val Glu Cys Cys Gln Gly Asp Trp Cys Asn 
65                  70                  75                  80  


Arg Asn Ile Thr Ala Gln Leu Pro Thr Lys Gly Lys Ser Phe Pro Gly 
                85                  90                  95      


Thr Gln Asn Phe His Leu Glu 
            100             


<210>  2354
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  2354

Asp Lys Asn Thr Thr Gln His Pro Asn Val Thr Thr Leu Ala Pro Ile 
1               5                   10                  15      


Ser Asn Val Thr Ser Ala Pro Val Thr Ser Leu Pro Leu Val Thr Thr 
            20                  25                  30          


Pro Ala Pro Glu Thr Cys Glu Gly Arg Asn Ser Cys Val Ser Cys Phe 
        35                  40                  45              


Asn Val Ser Val Val Asn Thr Thr Cys Phe Trp Ile Glu Cys Lys Asp 
    50                  55                  60                  


Glu Ser Tyr Cys Ser His Asn Ser Thr Val Ser Asp Cys Gln Val Gly 
65                  70                  75                  80  


Asn Thr Thr Asp Phe Cys Ser Val Ser Thr Ala Thr Pro Val Pro Thr 
                85                  90                  95      


Ala Asn Ser Thr Ala Lys Pro Thr Val Gln Pro Ser Pro Ser Thr Thr 
            100                 105                 110         


Ser Lys Thr Val Thr Thr Ser Gly Thr Thr Asn Asn Thr Val Thr Pro 
        115                 120                 125             


Thr Ser Gln Pro Val Arg Lys Ser Thr Phe Asp 
    130                 135                 


<210>  2355
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  2355

Ile Ala Glu Asn Glu Asp Ala Leu Leu Arg His Leu Phe Gln Gly Tyr 
1               5                   10                  15      


Gln Lys Trp Val Arg Pro Val Leu His Ser Asn Asp Thr Ile Lys Val 
            20                  25                  30          


Tyr Phe Gly Leu Lys Ile Ser Gln Leu Val Asp Val Asp Glu Lys Asn 
        35                  40                  45              


Gln Leu Met Thr Thr Asn Val Trp Leu Lys Gln Glu Trp Thr Asp His 
    50                  55                  60                  


Lys Leu Arg Trp Asn Pro Asp Asp Tyr Gly Gly Ile His Ser Ile Lys 
65                  70                  75                  80  


Val Pro Ser Glu Ser Leu Trp Leu Pro Asp Ile Val Leu Phe Glu Asn 
                85                  90                  95      


Ala Asp Gly Arg Phe Glu Gly Ser Leu Met Thr Lys Val Ile Val Lys 
            100                 105                 110         


Ser Asn Gly Thr Val Val Trp Thr Pro Pro Ala Ser Tyr Lys Ser Ser 
        115                 120                 125             


Cys Thr Met Asp Val Thr Phe Phe Pro Phe Asp Arg Gln Asn Cys Ser 
    130                 135                 140                 


Met Lys Phe Gly Ser Trp Thr Tyr Asp Gly Thr Met Val Asp Leu Ile 
145                 150                 155                 160 


Leu Ile Asn Glu Asn Val Asp Arg Lys Asp Phe Phe Asp Asn Gly Glu 
                165                 170                 175     


Trp Glu Ile Leu Asn Ala Lys Gly Met Lys Gly Asn Arg Arg Asp Gly 
            180                 185                 190         


Val Tyr Ser Tyr Pro Phe Ile Thr Tyr Ser Phe Val Leu Arg Arg Leu 
        195                 200                 205             


<210>  2356
<211>  602
<212>  PRT
<213>  Homo Sapiens

<400>  2356

Ile Asp Val Ser Gln Leu Val Asn Pro Ala Phe Pro Gly Thr Val Thr 
1               5                   10                  15      


Cys Asp Glu Arg Glu Ile Thr Val Glu Phe Pro Ser Ser Pro Gly Thr 
            20                  25                  30          


Lys Lys Trp His Ala Ser Val Val Asp Pro Leu Gly Leu Asp Met Pro 
        35                  40                  45              


Asn Cys Thr Tyr Ile Leu Asp Pro Glu Lys Leu Thr Leu Arg Ala Thr 
    50                  55                  60                  


Tyr Asp Asn Cys Thr Arg Arg Val His Gly Gly His Gln Met Thr Ile 
65                  70                  75                  80  


Arg Val Met Asn Asn Ser Ala Ala Leu Arg His Gly Ala Val Met Tyr 
                85                  90                  95      


Gln Phe Phe Cys Pro Ala Met Gln Val Glu Glu Thr Gln Gly Leu Ser 
            100                 105                 110         


Ala Ser Thr Ile Cys Gln Lys Asp Phe Met Ser Phe Ser Leu Pro Arg 
        115                 120                 125             


Val Phe Ser Gly Leu Ala Asp Asp Ser Lys Gly Thr Lys Val Gln Met 
    130                 135                 140                 


Gly Trp Ser Ile Glu Val Gly Asp Gly Ala Arg Ala Lys Thr Leu Thr 
145                 150                 155                 160 


Leu Pro Glu Ala Met Lys Glu Gly Phe Ser Leu Leu Ile Asp Asn His 
                165                 170                 175     


Arg Met Thr Phe His Val Pro Phe Asn Ala Thr Gly Val Thr His Tyr 
            180                 185                 190         


Val Gln Gly Asn Ser His Leu Tyr Met Val Ser Leu Lys Leu Thr Phe 
        195                 200                 205             


Ile Ser Pro Gly Gln Lys Val Ile Phe Ser Ser Gln Ala Ile Cys Ala 
    210                 215                 220                 


Pro Asp Pro Val Thr Cys Asn Ala Thr His Met Thr Leu Thr Ile Pro 
225                 230                 235                 240 


Glu Phe Pro Gly Lys Leu Lys Ser Val Ser Phe Glu Asn Gln Asn Ile 
                245                 250                 255     


Asp Val Ser Gln Leu His Asp Asn Gly Ile Asp Leu Glu Ala Thr Asn 
            260                 265                 270         


Gly Met Lys Leu His Phe Ser Lys Thr Leu Leu Lys Thr Lys Leu Ser 
        275                 280                 285             


Glu Lys Cys Leu Leu His Gln Phe Tyr Leu Ala Ser Leu Lys Leu Thr 
    290                 295                 300                 


Phe Leu Leu Arg Pro Glu Thr Val Ser Met Val Ile Tyr Pro Glu Cys 
305                 310                 315                 320 


Leu Cys Glu Ser Pro Val Ser Ile Val Thr Gly Glu Leu Cys Thr Gln 
                325                 330                 335     


Asp Gly Phe Met Asp Val Glu Val Tyr Ser Tyr Gln Thr Gln Pro Ala 
            340                 345                 350         


Leu Asp Leu Gly Thr Leu Arg Val Gly Asn Ser Ser Cys Gln Pro Val 
        355                 360                 365             


Phe Glu Ala Gln Ser Gln Gly Leu Val Arg Phe His Ile Pro Leu Asn 
    370                 375                 380                 


Gly Cys Gly Thr Arg Tyr Lys Phe Glu Asp Asp Lys Val Val Tyr Glu 
385                 390                 395                 400 


Asn Glu Ile His Ala Leu Trp Thr Asp Phe Pro Pro Ser Lys Ile Ser 
                405                 410                 415     


Arg Asp Ser Glu Phe Arg Met Thr Val Lys Cys Ser Tyr Ser Arg Asn 
            420                 425                 430         


Asp Met Leu Leu Asn Ile Asn Val Glu Ser Leu Thr Pro Pro Val Ala 
        435                 440                 445             


Ser Val Lys Leu Gly Pro Phe Thr Leu Ile Leu Gln Ser Tyr Pro Asp 
    450                 455                 460                 


Asn Ser Tyr Gln Gln Pro Tyr Gly Glu Asn Glu Tyr Pro Leu Val Arg 
465                 470                 475                 480 


Phe Leu Arg Gln Pro Ile Tyr Met Glu Val Arg Val Leu Asn Arg Asp 
                485                 490                 495     


Asp Pro Asn Ile Lys Leu Val Leu Asp Asp Cys Trp Ala Thr Ser Thr 
            500                 505                 510         


Met Asp Pro Asp Ser Phe Pro Gln Trp Asn Val Val Val Asp Gly Cys 
        515                 520                 525             


Ala Tyr Asp Leu Asp Asn Tyr Gln Thr Thr Phe His Pro Val Gly Ser 
    530                 535                 540                 


Ser Val Thr His Pro Asp His Tyr Gln Arg Phe Asp Met Lys Ala Phe 
545                 550                 555                 560 


Ala Phe Val Ser Glu Ala His Val Leu Ser Ser Leu Val Tyr Phe His 
                565                 570                 575     


Cys Ser Ala Leu Ile Cys Asn Arg Leu Ser Pro Asp Ser Pro Leu Cys 
            580                 585                 590         


Ser Val Thr Cys Pro Val Ser Ser Arg His 
        595                 600         


<210>  2357
<211>  617
<212>  PRT
<213>  Homo Sapiens

<400>  2357

Leu Pro Glu Gly Val Ala Asn Gly Ile Glu Val Tyr Ser Thr Lys Ile 
1               5                   10                  15      


Asn Ser Lys Val Thr Ser Arg Phe Ala His Asn Val Val Thr Met Arg 
            20                  25                  30          


Ala Val Asn Arg Ala Asp Thr Ala Lys Glu Val Ser Phe Asp Val Glu 
        35                  40                  45              


Leu Pro Lys Thr Ala Phe Ile Thr Asn Phe Thr Leu Thr Ile Asp Gly 
    50                  55                  60                  


Val Thr Tyr Pro Gly Asn Val Lys Glu Lys Glu Val Ala Lys Lys Gln 
65                  70                  75                  80  


Tyr Glu Lys Ala Val Ser Gln Gly Lys Thr Ala Gly Leu Val Lys Ala 
                85                  90                  95      


Ser Gly Arg Lys Leu Glu Lys Phe Thr Val Ser Val Asn Val Ala Ala 
            100                 105                 110         


Gly Ser Lys Val Thr Phe Glu Leu Thr Tyr Glu Glu Leu Leu Lys Arg 
        115                 120                 125             


His Lys Gly Lys Tyr Glu Met Tyr Leu Lys Val Gln Pro Lys Gln Leu 
    130                 135                 140                 


Val Lys His Phe Glu Ile Glu Val Asp Ile Phe Glu Pro Gln Gly Ile 
145                 150                 155                 160 


Ser Met Leu Asp Ala Glu Ala Ser Phe Ile Thr Asn Asp Leu Leu Gly 
                165                 170                 175     


Ser Ala Leu Thr Lys Ser Phe Ser Gly Lys Lys Gly His Val Ser Phe 
            180                 185                 190         


Lys Pro Ser Leu Asp Gln Gln Arg Ser Cys Pro Thr Cys Thr Asp Ser 
        195                 200                 205             


Leu Leu Asn Gly Asp Phe Thr Ile Thr Tyr Asp Val Asn Arg Glu Ser 
    210                 215                 220                 


Pro Gly Asn Val Gln Ile Val Asn Gly Tyr Phe Val His Phe Phe Ala 
225                 230                 235                 240 


Pro Gln Gly Leu Pro Val Val Pro Lys Asn Val Ala Phe Val Ile Asp 
                245                 250                 255     


Ile Ser Gly Ser Met Ala Gly Arg Lys Leu Glu Gln Thr Lys Glu Ala 
            260                 265                 270         


Leu Leu Arg Ile Leu Glu Asp Met Gln Glu Glu Asp Tyr Leu Asn Phe 
        275                 280                 285             


Ile Leu Phe Ser Gly Asp Val Ser Thr Trp Lys Glu His Leu Val Gln 
    290                 295                 300                 


Ala Thr Pro Glu Asn Leu Gln Glu Ala Arg Thr Phe Val Lys Ser Met 
305                 310                 315                 320 


Glu Asp Lys Gly Met Thr Asn Ile Asn Asp Gly Leu Leu Arg Gly Ile 
                325                 330                 335     


Ser Met Leu Asn Lys Ala Arg Glu Glu His Arg Ile Pro Glu Arg Ser 
            340                 345                 350         


Thr Ser Ile Val Ile Met Leu Thr Asp Gly Asp Ala Asn Val Gly Glu 
        355                 360                 365             


Ser Arg Pro Glu Lys Ile Gln Glu Asn Val Arg Asn Ala Ile Gly Gly 
    370                 375                 380                 


Lys Phe Pro Leu Tyr Asn Leu Gly Phe Gly Asn Asn Leu Asn Tyr Asn 
385                 390                 395                 400 


Phe Leu Glu Asn Met Ala Leu Glu Asn His Gly Phe Ala Arg Arg Ile 
                405                 410                 415     


Tyr Glu Asp Ser Asp Ala Asp Leu Gln Leu Gln Gly Phe Tyr Glu Glu 
            420                 425                 430         


Val Ala Asn Pro Leu Leu Thr Gly Val Glu Met Glu Tyr Pro Glu Asn 
        435                 440                 445             


Ala Ile Leu Asp Leu Thr Gln Asn Thr Tyr Gln His Phe Tyr Asp Gly 
    450                 455                 460                 


Ser Glu Ile Val Val Ala Gly Arg Leu Val Asp Glu Asp Met Asn Ser 
465                 470                 475                 480 


Phe Lys Ala Asp Val Lys Gly His Gly Ala Thr Asn Asp Leu Thr Phe 
                485                 490                 495     


Thr Glu Glu Val Asp Met Lys Glu Met Glu Lys Ala Leu Gln Glu Arg 
            500                 505                 510         


Asp Tyr Ile Phe Gly Asn Tyr Ile Glu Arg Leu Trp Ala Tyr Leu Thr 
        515                 520                 525             


Ile Glu Gln Leu Leu Glu Lys Arg Lys Asn Ala His Gly Glu Glu Lys 
    530                 535                 540                 


Glu Asn Leu Thr Ala Arg Ala Leu Asp Leu Ser Leu Lys Tyr His Phe 
545                 550                 555                 560 


Val Thr Pro Leu Thr Ser Met Val Val Thr Lys Pro Glu Asp Asn Glu 
                565                 570                 575     


Asp Glu Arg Ala Ile Ala Asp Lys Pro Gly Glu Asp Ala Glu Ala Thr 
            580                 585                 590         


Pro Val Ser Pro Ala Met Ser Tyr Leu Thr Ser Tyr Gln Pro Pro Gln 
        595                 600                 605             


Asn Pro Tyr Tyr Tyr Val Asp Gly Asp 
    610                 615         


<210>  2358
<211>  649
<212>  PRT
<213>  Homo Sapiens

<400>  2358

Gly Tyr Ile Glu Ala Leu Ala Ala Asn Ala Gly Thr Gly Phe Ala Val 
1               5                   10                  15      


Ala Glu Pro Gln Ile Ala Met Phe Cys Gly Lys Leu Asn Met His Val 
            20                  25                  30          


Asn Ile Gln Thr Gly Lys Trp Glu Pro Asp Pro Thr Gly Thr Lys Ser 
        35                  40                  45              


Cys Phe Glu Thr Lys Glu Glu Val Leu Gln Tyr Cys Gln Glu Met Tyr 
    50                  55                  60                  


Pro Glu Leu Gln Ile Thr Asn Val Met Glu Ala Asn Gln Arg Val Ser 
65                  70                  75                  80  


Ile Asp Asn Trp Cys Arg Arg Asp Lys Lys Gln Cys Lys Ser Arg Phe 
                85                  90                  95      


Val Thr Pro Phe Lys Cys Leu Val Gly Glu Phe Val Ser Asp Val Leu 
            100                 105                 110         


Leu Val Pro Glu Lys Cys Gln Phe Phe His Lys Glu Arg Met Glu Val 
        115                 120                 125             


Cys Glu Asn His Gln His Trp His Thr Val Val Lys Glu Ala Cys Leu 
    130                 135                 140                 


Thr Gln Gly Met Thr Leu Tyr Ser Tyr Gly Met Leu Leu Pro Cys Gly 
145                 150                 155                 160 


Val Asp Gln Phe His Gly Thr Glu Tyr Val Cys Cys Pro Gln Thr Lys 
                165                 170                 175     


Ile Ile Gly Ser Val Ser Lys Glu Glu Glu Glu Glu Asp Glu Glu Glu 
            180                 185                 190         


Glu Glu Glu Glu Asp Glu Glu Glu Asp Tyr Asp Val Tyr Lys Ser Glu 
        195                 200                 205             


Phe Pro Thr Glu Ala Asp Leu Glu Asp Phe Thr Glu Ala Ala Val Asp 
    210                 215                 220                 


Glu Asp Asp Glu Asp Glu Glu Glu Gly Glu Glu Val Val Glu Asp Arg 
225                 230                 235                 240 


Asp Tyr Tyr Tyr Asp Thr Phe Lys Gly Asp Asp Tyr Asn Glu Glu Asn 
                245                 250                 255     


Pro Thr Glu Pro Gly Ser Asp Gly Thr Met Ser Asp Lys Glu Ile Thr 
            260                 265                 270         


His Asp Val Lys Ala Val Cys Ser Gln Glu Ala Met Thr Gly Pro Cys 
        275                 280                 285             


Arg Ala Val Met Pro Arg Trp Tyr Phe Asp Leu Ser Lys Gly Lys Cys 
    290                 295                 300                 


Val Arg Phe Ile Tyr Gly Gly Cys Gly Gly Asn Arg Asn Asn Phe Glu 
305                 310                 315                 320 


Ser Glu Asp Tyr Cys Met Ala Val Cys Lys Ala Met Ile Pro Pro Thr 
                325                 330                 335     


Pro Leu Pro Thr Asn Asp Val Asp Val Tyr Phe Glu Thr Ser Ala Asp 
            340                 345                 350         


Asp Asn Glu His Ala Arg Phe Gln Lys Ala Lys Glu Gln Leu Glu Ile 
        355                 360                 365             


Arg His Arg Asn Arg Met Asp Arg Val Lys Lys Glu Trp Glu Glu Ala 
    370                 375                 380                 


Glu Leu Gln Ala Lys Asn Leu Pro Lys Ala Glu Arg Gln Thr Leu Ile 
385                 390                 395                 400 


Gln His Phe Gln Ala Met Val Lys Ala Leu Glu Lys Glu Ala Ala Ser 
                405                 410                 415     


Glu Lys Gln Gln Leu Val Glu Thr His Leu Ala Arg Val Glu Ala Met 
            420                 425                 430         


Leu Asn Asp Arg Arg Arg Met Ala Leu Glu Asn Tyr Leu Ala Ala Leu 
        435                 440                 445             


Gln Ser Asp Pro Pro Arg Pro His Arg Ile Leu Gln Ala Leu Arg Arg 
    450                 455                 460                 


Tyr Val Arg Ala Glu Asn Lys Asp Arg Leu His Thr Ile Arg His Tyr 
465                 470                 475                 480 


Gln His Val Leu Ala Val Asp Pro Glu Lys Ala Ala Gln Met Lys Ser 
                485                 490                 495     


Gln Val Met Thr His Leu His Val Ile Glu Glu Arg Arg Asn Gln Ser 
            500                 505                 510         


Leu Ser Leu Leu Tyr Lys Val Pro Tyr Val Ala Gln Glu Ile Gln Glu 
        515                 520                 525             


Glu Ile Asp Glu Leu Leu Gln Glu Gln Arg Ala Asp Met Asp Gln Phe 
    530                 535                 540                 


Thr Ala Ser Ile Ser Glu Thr Pro Val Asp Val Arg Val Ser Ser Glu 
545                 550                 555                 560 


Glu Ser Glu Glu Ile Pro Pro Phe His Pro Phe His Pro Phe Pro Ala 
                565                 570                 575     


Leu Pro Glu Asn Glu Gly Ser Gly Val Gly Glu Gln Asp Gly Gly Leu 
            580                 585                 590         


Ile Gly Ala Glu Glu Lys Val Ile Asn Ser Lys Asn Lys Val Asp Glu 
        595                 600                 605             


Asn Met Val Ile Asp Glu Thr Leu Asp Val Lys Glu Met Ile Phe Asn 
    610                 615                 620                 


Ala Glu Arg Val Gly Gly Leu Glu Glu Glu Arg Glu Ser Val Gly Pro 
625                 630                 635                 640 


Leu Arg Glu Asp Phe Ser Leu Ser Ser 
                645                 


<210>  2359
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2359

Pro Ile Ile Met Gly Ser Asn Ile Gly Thr Ser Val Thr Asn Thr Ile 
1               5                   10                  15      


Val Ala Leu Met Gln Ala Gly Asp Arg Thr Asp Phe Arg Arg Ala Phe 
            20                  25                  30          


Ala Gly Ala Thr Val His Asp Cys Phe Asn Trp Leu Ser Val Leu Val 
        35                  40                  45              


Leu Leu Pro Leu Glu Ala Ala Thr Gly Tyr Leu His His Ile Thr Arg 
    50                  55                  60                  


Leu Val Val Ala Ser Phe Asn Ile His Gly Gly Arg Asp Ala Pro Asp 
65                  70                  75                  80  


Leu Leu Lys Ile Ile Thr Glu Pro Phe Thr Lys Leu Ile Ile Gln Leu 
                85                  90                  95      


Asp Glu Ser Val Ile Thr Ser Ile Ala Thr Gly Asp Glu Ser Leu Arg 
            100                 105                 110         


Asn His Ser Leu Ile Gln Ile Trp Cys His Pro Asp Ser Leu Gln Ala 
        115                 120                 125             


Pro Thr Ser Met Ser Arg Ala Glu Ala Asn Ser Ser Gln Thr Leu Gly 
    130                 135                 140                 


Asn Ala Thr Met Glu Lys Cys Asn His Ile Phe Val Asp Thr Gly Leu 
145                 150                 155                 160 


Pro Asp 
        


<210>  2360
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2360

Leu Asn Glu Glu Glu Arg Leu Ile Arg His Leu Phe Gln Glu Lys Gly 
1               5                   10                  15      


Tyr Asn Lys Glu Leu Arg Pro Val Ala His Lys Glu Glu Ser Val Asp 
            20                  25                  30          


Val Ala Leu Ala Leu Thr Leu Ser Asn Leu Ile Ser Leu Lys Glu Val 
        35                  40                  45              


Glu Glu Thr Leu Thr Thr Asn Val Trp Ile Glu His Gly Trp Thr Asp 
    50                  55                  60                  


Asn Arg Leu Lys Trp Asn Ala Glu Glu Phe Gly Asn Ile Ser Val Leu 
65                  70                  75                  80  


Arg Leu Pro Pro Asp Met Val Trp Leu Pro Glu Ile Val Leu Glu Asn 
                85                  90                  95      


Asn Asn Asp Gly Ser Phe Gln Ile Ser Tyr Ser Cys Asn Val Leu Val 
            100                 105                 110         


Tyr His Tyr Gly Phe Val Tyr Trp Leu Pro Pro Ala Ile Phe Arg Ser 
        115                 120                 125             


Ser Cys Pro Ile Ser Val Thr Tyr Phe Pro Phe Asp Trp Gln Asn Cys 
    130                 135                 140                 


Ser Leu Lys Phe Ser Ser Leu Lys Tyr Thr Ala Lys Glu Ile Thr Leu 
145                 150                 155                 160 


Ser Leu Lys Gln Asp Ala Lys Glu Asn Arg Thr Tyr Pro Val Glu Trp 
                165                 170                 175     


Ile Ile Ile Asp Pro Glu Gly Phe Thr Glu Asn Gly Glu Trp Glu Ile 
            180                 185                 190         


Val His Arg Pro Ala Arg Val Asn Val Asp Pro Arg Ala Pro Leu Asp 
        195                 200                 205             


Ser Pro Ser Arg Gln Asp Ile Thr Phe Tyr Leu Ile Ile Arg Arg Lys 
    210                 215                 220                 


<210>  2361
<211>  209
<212>  PRT
<213>  Homo Sapiens

<400>  2361

Leu His Thr Asp Gly Asp Lys Ala Phe Val Asp Phe Leu Ser Asp Glu 
1               5                   10                  15      


Ile Lys Glu Glu Arg Lys Ile Gln Lys His Lys Thr Leu Pro Lys Met 
            20                  25                  30          


Ser Gly Gly Trp Glu Leu Glu Leu Asn Gly Thr Glu Ala Lys Leu Val 
        35                  40                  45              


Arg Lys Val Ala Gly Glu Lys Ile Thr Val Thr Phe Asn Ile Asn Asn 
    50                  55                  60                  


Ser Ile Pro Pro Thr Phe Asp Gly Glu Glu Glu Pro Ser Gln Gly Gln 
65                  70                  75                  80  


Lys Val Glu Glu Gln Glu Pro Glu Leu Thr Ser Thr Pro Asn Phe Val 
                85                  90                  95      


Val Glu Val Ile Lys Asn Asp Asp Gly Lys Lys Ala Leu Val Leu Asp 
            100                 105                 110         


Cys His Tyr Pro Glu Asp Glu Val Gly Gln Glu Asp Glu Ala Glu Ser 
        115                 120                 125             


Asp Ile Phe Ser Ile Arg Glu Val Ser Phe Gln Ser Thr Gly Glu Ser 
    130                 135                 140                 


Glu Trp Lys Asp Thr Asn Tyr Thr Leu Asn Thr Asp Ser Leu Asp Trp 
145                 150                 155                 160 


Ala Leu Tyr Asp His Leu Met Asp Phe Leu Ala Asp Arg Gly Val Asp 
                165                 170                 175     


Asn Thr Phe Ala Asp Glu Leu Val Glu Leu Ser Thr Ala Leu Glu His 
            180                 185                 190         


Gln Glu Tyr Ile Thr Phe Leu Glu Asp Leu Lys Ser Phe Val Lys Ser 
        195                 200                 205             


Gln 
    


<210>  2362
<211>  918
<212>  PRT
<213>  Homo Sapiens

<400>  2362

Thr Arg Ser Cys Asp Ser Ser Gly Asp Gly Gly Pro Gly Thr Ala Pro 
1               5                   10                  15      


Ala Pro Ser His Leu Pro Ser Ser Thr Ala Ser Pro Ser Gly Pro Pro 
            20                  25                  30          


Ala Gln Asp Gln Asp Ile Cys Pro Ala Ser Glu Asp Glu Ser Gly Gln 
        35                  40                  45              


Trp Lys Asn Phe Arg Leu Pro Asp Phe Val Asn Pro Val His Tyr Asp 
    50                  55                  60                  


Leu His Val Lys Pro Leu Leu Glu Glu Asp Thr Tyr Thr Gly Thr Val 
65                  70                  75                  80  


Ser Ile Ser Ile Asn Leu Ser Ala Pro Thr Arg Tyr Leu Trp Leu His 
                85                  90                  95      


Leu Arg Glu Thr Arg Ile Thr Arg Leu Pro Glu Leu Lys Arg Pro Ser 
            100                 105                 110         


Gly Asp Gln Val Gln Val Arg Arg Cys Phe Glu Tyr Lys Lys Gln Glu 
        115                 120                 125             


Tyr Val Val Val Glu Ala Glu Glu Glu Leu Thr Pro Ser Ser Gly Asp 
    130                 135                 140                 


Gly Leu Tyr Leu Leu Thr Met Glu Phe Ala Gly Trp Leu Asn Gly Ser 
145                 150                 155                 160 


Leu Val Gly Phe Tyr Arg Thr Thr Tyr Thr Glu Asn Gly Arg Val Lys 
                165                 170                 175     


Ser Ile Val Ala Thr Asp His Glu Pro Thr Asp Ala Arg Lys Ser Phe 
            180                 185                 190         


Pro Cys Phe Asp Glu Pro Asn Lys Lys Ala Thr Tyr Thr Ile Ser Ile 
        195                 200                 205             


Thr His Pro Lys Glu Tyr Gly Ala Leu Ser Asn Met Pro Val Ala Lys 
    210                 215                 220                 


Glu Glu Ser Val Asp Asp Lys Trp Thr Arg Thr Thr Phe Glu Lys Ser 
225                 230                 235                 240 


Val Pro Met Ser Thr Tyr Leu Val Cys Phe Ala Val His Gln Phe Asp 
                245                 250                 255     


Ser Val Lys Arg Ile Ser Asn Ser Gly Lys Pro Leu Thr Ile Tyr Val 
            260                 265                 270         


Gln Pro Glu Gln Lys His Thr Ala Glu Tyr Ala Ala Asn Ile Thr Lys 
        275                 280                 285             


Ser Val Phe Asp Tyr Phe Glu Glu Tyr Phe Ala Met Asn Tyr Ser Leu 
    290                 295                 300                 


Pro Lys Leu Asp Lys Ile Ala Ile Pro Asp Phe Gly Thr Gly Ala Met 
305                 310                 315                 320 


Glu Asn Trp Gly Leu Ile Thr Tyr Arg Glu Thr Asn Leu Leu Tyr Asp 
                325                 330                 335     


Pro Lys Glu Ser Ala Ser Ser Asn Gln Gln Arg Val Ala Thr Val Val 
            340                 345                 350         


Ala His Glu Leu Val His Gln Trp Phe Gly Asn Ile Val Thr Met Asp 
        355                 360                 365             


Trp Trp Glu Asp Leu Trp Leu Asn Glu Gly Phe Ala Ser Phe Phe Glu 
    370                 375                 380                 


Phe Leu Gly Val Asn His Ala Glu Thr Asp Trp Gln Met Arg Asp Gln 
385                 390                 395                 400 


Met Leu Leu Glu Asp Val Leu Pro Val Gln Glu Asp Asp Ser Leu Met 
                405                 410                 415     


Ser Ser His Pro Ile Ile Val Thr Val Thr Thr Pro Asp Glu Ile Thr 
            420                 425                 430         


Ser Val Phe Asp Gly Ile Ser Tyr Ser Lys Gly Ser Ser Ile Leu Arg 
        435                 440                 445             


Met Leu Glu Asp Trp Ile Lys Pro Glu Asn Phe Gln Lys Gly Cys Gln 
    450                 455                 460                 


Met Tyr Leu Glu Lys Tyr Gln Phe Lys Asn Ala Lys Thr Ser Asp Phe 
465                 470                 475                 480 


Trp Ala Ala Leu Glu Glu Ala Ser Arg Leu Pro Val Lys Glu Val Met 
                485                 490                 495     


Asp Thr Trp Thr Arg Gln Met Gly Tyr Pro Val Leu Asn Val Asn Gly 
            500                 505                 510         


Val Lys Asn Ile Thr Gln Lys Arg Phe Leu Leu Asp Pro Arg Ala Asn 
        515                 520                 525             


Pro Ser Gln Pro Pro Ser Asp Leu Gly Tyr Thr Trp Asn Ile Pro Val 
    530                 535                 540                 


Lys Trp Thr Glu Asp Asn Ile Thr Ser Ser Val Leu Phe Asn Arg Ser 
545                 550                 555                 560 


Glu Lys Glu Gly Ile Thr Leu Asn Ser Ser Asn Pro Ser Gly Asn Ala 
                565                 570                 575     


Phe Leu Lys Ile Asn Pro Asp His Ile Gly Phe Tyr Arg Val Asn Tyr 
            580                 585                 590         


Glu Val Ala Thr Trp Asp Ser Ile Ala Thr Ala Leu Ser Leu Asn His 
        595                 600                 605             


Lys Thr Phe Ser Ser Ala Asp Arg Ala Ser Leu Ile Asp Asp Ala Phe 
    610                 615                 620                 


Ala Leu Ala Arg Ala Gln Leu Leu Asp Tyr Lys Val Ala Leu Asn Leu 
625                 630                 635                 640 


Thr Lys Tyr Leu Lys Arg Glu Glu Asn Phe Leu Pro Trp Gln Arg Val 
                645                 650                 655     


Ile Ser Ala Val Thr Tyr Ile Ile Ser Met Phe Glu Asp Asp Lys Glu 
            660                 665                 670         


Leu Tyr Pro Met Ile Glu Glu Tyr Phe Gln Gly Gln Val Lys Pro Ile 
        675                 680                 685             


Ala Asp Ser Leu Gly Trp Asn Asp Ala Gly Asp His Val Thr Lys Leu 
    690                 695                 700                 


Leu Arg Ser Ser Val Leu Gly Phe Ala Cys Lys Met Gly Asp Arg Glu 
705                 710                 715                 720 


Ala Leu Asn Asn Ala Ser Ser Leu Phe Glu Gln Trp Leu Asn Gly Thr 
                725                 730                 735     


Val Ser Leu Pro Val Asn Leu Arg Leu Leu Val Tyr Arg Tyr Gly Met 
            740                 745                 750         


Gln Asn Ser Gly Asn Glu Ile Ser Trp Asn Tyr Thr Leu Glu Gln Tyr 
        755                 760                 765             


Gln Lys Thr Ser Leu Ala Gln Glu Lys Glu Lys Leu Leu Tyr Gly Leu 
    770                 775                 780                 


Ala Ser Val Lys Asn Val Thr Leu Leu Ser Arg Tyr Leu Asp Leu Leu 
785                 790                 795                 800 


Lys Asp Thr Asn Leu Ile Lys Thr Gln Asp Val Phe Thr Val Ile Arg 
                805                 810                 815     


Tyr Ile Ser Tyr Asn Ser Tyr Gly Lys Asn Met Ala Trp Asn Trp Ile 
            820                 825                 830         


Gln Leu Asn Trp Asp Tyr Leu Val Asn Arg Tyr Thr Leu Asn Asn Arg 
        835                 840                 845             


Asn Leu Gly Arg Ile Val Thr Ile Ala Glu Pro Phe Asn Thr Glu Leu 
    850                 855                 860                 


Gln Leu Trp Gln Met Glu Ser Phe Phe Ala Lys Tyr Pro Gln Ala Gly 
865                 870                 875                 880 


Ala Gly Glu Lys Pro Arg Glu Gln Val Leu Glu Thr Val Lys Asn Asn 
                885                 890                 895     


Ile Glu Trp Leu Lys Gln His Arg Asn Thr Ile Arg Glu Trp Phe Phe 
            900                 905                 910         


Asn Leu Leu Glu Ser Gly 
        915             


<210>  2363
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2363

Gln Tyr Gly Asp Tyr Gly Tyr Pro Tyr Gln Gln Tyr His Asp Tyr Ser 
1               5                   10                  15      


Asp Asp Gly Trp Val Asn Leu Asn Arg Gln Gly Phe Ser Tyr Gln Cys 
            20                  25                  30          


Pro Gln Gly Gln Val Ile Val Ala Val Arg Ser Ile Phe Ser Lys Lys 
        35                  40                  45              


Glu Gly Ser Asp Arg Gln Trp Asn Tyr Ala Cys Met Pro Thr Pro Gln 
    50                  55                  60                  


Ser Leu Gly Glu Pro Thr Glu Cys Trp Trp Glu Glu Ile Asn Arg Ala 
65                  70                  75                  80  


Gly Met Glu Trp Tyr Gln Thr Cys Ser Asn Asn Gly Leu Val Ala Gly 
                85                  90                  95      


Phe Gln Ser Arg Tyr Phe Glu Ser Val Leu Asp Arg Glu Trp Gln Phe 
            100                 105                 110         


Tyr Cys Cys Arg Tyr Ser Lys Arg Cys Pro Tyr Ser Cys Trp Leu Thr 
        115                 120                 125             


Ile Glu Tyr Pro Gly His Tyr Gly Glu Glu Met Asp Met Ile Ser Tyr 
    130                 135                 140                 


Asn Tyr Asp Tyr Tyr Ile Arg Gly Ala Thr Thr Thr Phe Ser Ala Val 
145                 150                 155                 160 


Glu Arg Asp Arg Gln Trp Lys Phe Ile Met Cys Arg Met Thr Glu Tyr 
                165                 170                 175     


Asp Cys Glu Phe Ala Asn Val 
            180             


<210>  2364
<211>  577
<212>  PRT
<213>  Homo Sapiens

<400>  2364

Ala Leu Ser Pro Lys Cys Leu Asp Trp Trp Gln Glu Gly Pro Met Tyr 
1               5                   10                  15      


Gln Ile Tyr Pro Arg Ser Phe Lys Asp Ser Asn Lys Asp Gly Asn Gly 
            20                  25                  30          


Asp Leu Lys Gly Ile Gln Asp Lys Leu Asp Tyr Ile Thr Ala Leu Asn 
        35                  40                  45              


Ile Lys Thr Val Trp Ile Thr Ser Phe Tyr Lys Ser Ser Leu Lys Asp 
    50                  55                  60                  


Phe Arg Tyr Gly Val Glu Asp Phe Arg Glu Val Asp Pro Ile Phe Gly 
65                  70                  75                  80  


Thr Met Glu Asp Phe Glu Asn Leu Val Ala Ala Ile His Asp Lys Gly 
                85                  90                  95      


Leu Lys Leu Ile Ile Asp Phe Ile Pro Asn His Thr Ser Asp Lys His 
            100                 105                 110         


Ile Trp Phe Gln Leu Ser Arg Thr Arg Thr Gly Lys Tyr Thr Asp Tyr 
        115                 120                 125             


Tyr Ile Trp His Asp Cys Thr His Glu Asn Gly Lys Thr Ile Pro Pro 
    130                 135                 140                 


Asn Asn Trp Leu Ser Val Tyr Gly Asn Ser Ser Trp His Phe Asp Glu 
145                 150                 155                 160 


Val Arg Asn Gln Cys Tyr Phe His Gln Phe Met Lys Glu Gln Pro Asp 
                165                 170                 175     


Leu Asn Phe Arg Asn Pro Asp Val Gln Glu Glu Ile Lys Glu Ile Leu 
            180                 185                 190         


Arg Phe Trp Leu Thr Lys Gly Val Asp Gly Phe Ser Leu Asp Ala Val 
        195                 200                 205             


Lys Phe Leu Leu Glu Ala Lys His Leu Arg Asp Glu Ile Gln Val Asn 
    210                 215                 220                 


Lys Thr Gln Ile Pro Asp Thr Val Thr Gln Tyr Ser Glu Leu Tyr His 
225                 230                 235                 240 


Asp Phe Thr Thr Thr Gln Val Gly Met His Asp Ile Val Arg Ser Phe 
                245                 250                 255     


Arg Gln Thr Met Asp Gln Tyr Ser Thr Glu Pro Gly Arg Tyr Arg Phe 
            260                 265                 270         


Met Gly Thr Glu Ala Tyr Ala Glu Ser Ile Asp Arg Thr Val Met Tyr 
        275                 280                 285             


Tyr Gly Leu Pro Phe Ile Gln Glu Ala Asp Phe Pro Phe Asn Asn Tyr 
    290                 295                 300                 


Leu Ser Met Leu Asp Thr Val Ser Gly Asn Ser Val Tyr Glu Val Ile 
305                 310                 315                 320 


Thr Ser Trp Met Glu Asn Met Pro Glu Gly Lys Trp Pro Asn Trp Met 
                325                 330                 335     


Ile Gly Gly Pro Asp Ser Ser Arg Leu Thr Ser Arg Leu Gly Asn Gln 
            340                 345                 350         


Tyr Val Asn Val Met Asn Met Leu Leu Phe Thr Leu Pro Gly Thr Pro 
        355                 360                 365             


Ile Thr Tyr Tyr Gly Glu Glu Ile Gly Met Gly Asn Ile Val Ala Ala 
    370                 375                 380                 


Asn Leu Asn Glu Ser Tyr Asp Ile Asn Thr Leu Arg Ser Lys Ser Pro 
385                 390                 395                 400 


Met Gln Trp Asp Asn Ser Ser Asn Ala Gly Phe Ser Glu Ala Ser Asn 
                405                 410                 415     


Thr Trp Leu Pro Thr Asn Ser Asp Tyr His Thr Val Asn Val Asp Val 
            420                 425                 430         


Gln Lys Thr Gln Pro Arg Ser Ala Leu Lys Leu Tyr Gln Asp Leu Ser 
        435                 440                 445             


Leu Leu His Ala Asn Glu Leu Leu Leu Asn Arg Gly Trp Phe Cys His 
    450                 455                 460                 


Leu Arg Asn Asp Ser His Tyr Val Val Tyr Thr Arg Glu Leu Asp Gly 
465                 470                 475                 480 


Ile Asp Arg Ile Phe Ile Val Val Leu Asn Phe Gly Glu Ser Thr Leu 
                485                 490                 495     


Leu Asn Leu His Asn Met Ile Ser Gly Leu Pro Ala Lys Ile Arg Ile 
            500                 505                 510         


Arg Leu Ser Thr Asn Ser Ala Asp Lys Gly Ser Lys Val Asp Thr Ser 
        515                 520                 525             


Gly Ile Phe Leu Asp Lys Gly Glu Gly Leu Ile Phe Glu His Asn Thr 
    530                 535                 540                 


Lys Asn Leu Leu His Arg Gln Thr Ala Phe Arg Asp Arg Cys Phe Val 
545                 550                 555                 560 


Ser Asn Arg Ala Cys Tyr Ser Ser Val Leu Asn Ile Leu Tyr Thr Ser 
                565                 570                 575     


Cys 
    


<210>  2365
<211>  397
<212>  PRT
<213>  Homo Sapiens

<400>  2365

Asp Met Lys Gly His Phe Asp Pro Ala Lys Cys Arg Tyr Ala Leu Gly 
1               5                   10                  15      


Met Gln Asp Arg Thr Ile Pro Asp Ser Asp Ile Ser Ala Ser Ser Ser 
            20                  25                  30          


Trp Ser Asp Ser Thr Ala Ala Arg His Ser Arg Leu Glu Ser Ser Asp 
        35                  40                  45              


Gly Asp Gly Ala Trp Cys Pro Ala Gly Ser Val Phe Pro Lys Glu Glu 
    50                  55                  60                  


Glu Tyr Leu Gln Val Asp Leu Gln Arg Leu His Leu Val Ala Leu Val 
65                  70                  75                  80  


Gly Thr Gln Gly Arg His Ala Gly Gly Leu Gly Lys Glu Phe Ser Arg 
                85                  90                  95      


Ser Tyr Arg Leu Arg Tyr Ser Arg Asp Gly Arg Arg Trp Met Gly Trp 
            100                 105                 110         


Lys Asp Arg Trp Gly Gln Glu Val Ile Ser Gly Asn Glu Asp Pro Glu 
        115                 120                 125             


Gly Val Val Leu Lys Asp Leu Gly Pro Pro Met Val Ala Arg Leu Val 
    130                 135                 140                 


His Phe Tyr Pro Arg Ala Asp Arg Val Met Ser Val Cys Leu Arg Val 
145                 150                 155                 160 


Glu Leu Tyr Gly Cys Leu Trp Arg Asp Gly Leu Leu Ser Tyr Thr Ala 
                165                 170                 175     


Pro Val Gly Gln Thr Met Tyr Leu Ser Glu Ala Val Tyr Leu Asn Asp 
            180                 185                 190         


Ser Thr Tyr Asp Gly His Thr Val Gly Gly Leu Gln Tyr Gly Gly Leu 
        195                 200                 205             


Gly Gln Leu Ala Asp Gly Val Val Gly Leu Asp Asp Phe Arg Lys Ser 
    210                 215                 220                 


Gln Glu Leu Arg Val Trp Pro Gly Tyr Asp Tyr Val Gly Trp Ser Asn 
225                 230                 235                 240 


His Ser Phe Ser Ser Gly Tyr Val Glu Met Glu Phe Glu Phe Asp Arg 
                245                 250                 255     


Leu Arg Ala Phe Gln Ala Met Gln Val His Cys Asn Asn Met His Thr 
            260                 265                 270         


Leu Gly Ala Arg Leu Pro Gly Gly Val Glu Cys Arg Phe Arg Arg Gly 
        275                 280                 285             


Pro Ala Met Ala Trp Glu Gly Glu Pro Met Arg His Asn Leu Gly Gly 
    290                 295                 300                 


Asn Leu Gly Asp Pro Arg Ala Arg Ala Val Ser Val Pro Leu Gly Gly 
305                 310                 315                 320 


Arg Val Ala Arg Phe Leu Gln Cys Arg Phe Leu Phe Ala Gly Pro Trp 
                325                 330                 335     


Leu Leu Phe Ser Glu Ile Ser Phe Ile Ser Asp Val Val Asn Asn Ser 
            340                 345                 350         


Ser Pro Ala Leu Gly Gly Thr Phe Pro Pro Ala Pro Trp Trp Pro Pro 
        355                 360                 365             


Gly Pro Pro Pro Thr Asn Phe Ser Ser Leu Glu Leu Glu Pro Arg Gly 
    370                 375                 380                 


Gln Gln Pro Val Ala Lys Ala Glu Gly Ser Pro Thr Ala 
385                 390                 395         


<210>  2366
<211>  567
<212>  PRT
<213>  Homo Sapiens

<400>  2366

Val Asn Asp Gly Asp Met Arg Leu Ala Asp Gly Gly Ala Thr Asn Gln 
1               5                   10                  15      


Gly Arg Val Glu Ile Phe Tyr Arg Gly Gln Trp Gly Thr Val Cys Asp 
            20                  25                  30          


Asn Leu Trp Asp Leu Thr Asp Ala Ser Val Val Cys Arg Ala Leu Gly 
        35                  40                  45              


Phe Glu Asn Ala Thr Gln Ala Leu Gly Arg Ala Ala Phe Gly Gln Gly 
    50                  55                  60                  


Ser Gly Pro Ile Met Leu Asp Glu Val Gln Cys Thr Gly Thr Glu Ala 
65                  70                  75                  80  


Ser Leu Ala Asp Cys Lys Ser Leu Gly Trp Leu Lys Ser Asn Cys Arg 
                85                  90                  95      


His Glu Arg Asp Ala Gly Val Val Cys Thr Asn Glu Thr Arg Ser Thr 
            100                 105                 110         


His Thr Leu Asp Leu Ser Arg Glu Leu Ser Glu Ala Leu Gly Gln Ile 
        115                 120                 125             


Phe Asp Ser Gln Arg Gly Cys Asp Leu Ser Ile Ser Val Asn Val Gln 
    130                 135                 140                 


Gly Glu Asp Ala Leu Gly Phe Cys Gly His Thr Val Ile Leu Thr Ala 
145                 150                 155                 160 


Asn Leu Glu Ala Gln Ala Leu Trp Lys Glu Pro Gly Ser Asn Val Thr 
                165                 170                 175     


Met Ser Val Asp Ala Glu Cys Val Pro Met Val Arg Asp Leu Leu Arg 
            180                 185                 190         


Tyr Phe Tyr Ser Arg Arg Ile Asp Ile Thr Leu Ser Ser Val Lys Cys 
        195                 200                 205             


Phe His Lys Leu Ala Ser Ala Tyr Gly Ala Arg Gln Leu Gln Gly Tyr 
    210                 215                 220                 


Cys Ala Ser Leu Phe Ala Ile Leu Leu Pro Gln Asp Pro Ser Phe Gln 
225                 230                 235                 240 


Met Pro Leu Asp Leu Tyr Ala Tyr Ala Val Ala Thr Gly Asp Ala Leu 
                245                 250                 255     


Leu Glu Lys Leu Cys Leu Gln Phe Leu Ala Trp Asn Phe Glu Ala Leu 
            260                 265                 270         


Thr Gln Ala Glu Ala Trp Pro Ser Val Pro Thr Asp Leu Leu Gln Leu 
        275                 280                 285             


Leu Leu Pro Arg Ser Asp Leu Ala Val Pro Ser Glu Leu Ala Leu Leu 
    290                 295                 300                 


Lys Ala Val Asp Thr Trp Ser Trp Gly Glu Arg Ala Ser His Glu Glu 
305                 310                 315                 320 


Val Glu Gly Leu Val Glu Lys Ile Arg Phe Pro Met Met Leu Pro Glu 
                325                 330                 335     


Glu Leu Phe Glu Leu Gln Phe Asn Leu Ser Leu Tyr Trp Ser His Glu 
            340                 345                 350         


Ala Leu Phe Gln Lys Lys Thr Leu Gln Ala Leu Glu Phe His Thr Val 
        355                 360                 365             


Pro Phe Gln Leu Leu Ala Arg Tyr Lys Gly Leu Asn Leu Thr Glu Asp 
    370                 375                 380                 


Thr Tyr Lys Pro Arg Ile Tyr Thr Ser Pro Thr Trp Ser Ala Phe Val 
385                 390                 395                 400 


Thr Asp Ser Ser Trp Ser Ala Arg Lys Ser Gln Leu Val Tyr Gln Ser 
                405                 410                 415     


Arg Arg Gly Pro Leu Val Lys Tyr Ser Ser Asp Tyr Phe Gln Ala Pro 
            420                 425                 430         


Ser Asp Tyr Arg Tyr Tyr Pro Tyr Gln Ser Phe Gln Thr Pro Gln His 
        435                 440                 445             


Pro Ser Phe Leu Phe Gln Asp Lys Arg Val Ser Trp Ser Leu Val Tyr 
    450                 455                 460                 


Leu Pro Thr Ile Gln Ser Cys Trp Asn Tyr Gly Phe Ser Cys Ser Ser 
465                 470                 475                 480 


Asp Glu Leu Pro Val Leu Gly Leu Thr Lys Ser Gly Gly Ser Asp Arg 
                485                 490                 495     


Thr Ile Ala Tyr Glu Asn Lys Ala Leu Met Leu Cys Glu Gly Leu Phe 
            500                 505                 510         


Val Ala Asp Val Thr Asp Phe Glu Gly Trp Lys Ala Ala Ile Pro Ser 
        515                 520                 525             


Ala Leu Asp Thr Asn Ser Ser Lys Ser Thr Ser Ser Phe Pro Cys Pro 
    530                 535                 540                 


Ala Gly His Phe Asn Gly Phe Arg Thr Val Ile Arg Pro Phe Tyr Leu 
545                 550                 555                 560 


Thr Asn Ser Ser Gly Val Asp 
                565         


<210>  2367
<211>  557
<212>  PRT
<213>  Homo Sapiens

<400>  2367

Arg Trp Ala Pro Ile Pro Ala Ser Leu Met Glu Asn Ser Leu Gly Pro 
1               5                   10                  15      


Phe Pro Gln His Val Gln Gln Ile Gln Ser Asp Ala Ala Gln Asn Tyr 
            20                  25                  30          


Thr Ile Phe Tyr Ser Ile Ser Gly Pro Gly Val Asp Lys Glu Pro Phe 
        35                  40                  45              


Asn Leu Phe Tyr Ile Glu Lys Asp Thr Gly Asp Ile Phe Cys Thr Arg 
    50                  55                  60                  


Ser Ile Asp Arg Glu Lys Tyr Glu Gln Phe Ala Leu Tyr Gly Tyr Ala 
65                  70                  75                  80  


Thr Thr Ala Asp Gly Tyr Ala Pro Glu Tyr Pro Leu Pro Leu Ile Ile 
                85                  90                  95      


Lys Ile Glu Asp Asp Asn Asp Asn Ala Pro Tyr Phe Glu His Arg Val 
            100                 105                 110         


Thr Ile Phe Thr Val Pro Glu Asn Cys Arg Ser Gly Thr Ser Val Gly 
        115                 120                 125             


Lys Val Thr Ala Thr Asp Leu Asp Glu Pro Asp Thr Leu His Thr Arg 
    130                 135                 140                 


Leu Lys Tyr Lys Ile Leu Gln Gln Ile Pro Asp His Pro Lys His Phe 
145                 150                 155                 160 


Ser Ile His Pro Asp Thr Gly Val Ile Thr Thr Thr Thr Pro Phe Leu 
                165                 170                 175     


Asp Arg Glu Lys Cys Asp Thr Tyr Gln Leu Ile Met Glu Val Arg Asp 
            180                 185                 190         


Met Gly Gly Gln Pro Phe Gly Leu Phe Asn Thr Gly Thr Ile Thr Ile 
        195                 200                 205             


Ser Leu Glu Asp Glu Asn Asp Asn Pro Pro Ser Phe Thr Glu Thr Ser 
    210                 215                 220                 


Tyr Val Thr Glu Val Glu Glu Asn Arg Ile Asp Val Glu Ile Leu Arg 
225                 230                 235                 240 


Met Lys Val Gln Asp Gln Asp Leu Pro Asn Thr Pro His Ser Lys Ala 
                245                 250                 255     


Val Tyr Lys Ile Leu Gln Gly Asn Glu Asn Gly Asn Phe Ile Ile Ser 
            260                 265                 270         


Thr Asp Pro Asn Thr Asn Glu Gly Val Leu Cys Val Val Lys Pro Leu 
        275                 280                 285             


Asn Tyr Glu Val Asn Arg Gln Val Ile Leu Gln Val Gly Val Ile Asn 
    290                 295                 300                 


Glu Ala Gln Phe Ser Lys Ala Ala Ser Ser Gln Thr Pro Thr Met Cys 
305                 310                 315                 320 


Thr Thr Thr Val Thr Val Lys Ile Ile Asp Ser Asp Glu Gly Pro Glu 
                325                 330                 335     


Cys His Pro Pro Val Lys Val Ile Gln Ser Gln Asp Gly Phe Pro Ala 
            340                 345                 350         


Gly Gln Glu Leu Leu Gly Tyr Lys Ala Leu Asp Pro Glu Ile Ser Ser 
        355                 360                 365             


Gly Glu Gly Leu Arg Tyr Gln Lys Leu Gly Asp Glu Asp Asn Trp Phe 
    370                 375                 380                 


Glu Ile Asn Gln His Thr Gly Asp Leu Arg Thr Leu Lys Val Leu Asp 
385                 390                 395                 400 


Arg Glu Ser Lys Phe Val Lys Asn Asn Gln Tyr Asn Ile Ser Val Val 
                405                 410                 415     


Ala Val Asp Ala Val Gly Arg Ser Cys Thr Gly Thr Leu Val Val His 
            420                 425                 430         


Leu Asp Asp Tyr Asn Asp His Ala Pro Gln Ile Asp Lys Glu Val Thr 
        435                 440                 445             


Ile Cys Gln Asn Asn Glu Asp Phe Ala Val Leu Lys Pro Val Asp Pro 
    450                 455                 460                 


Asp Gly Pro Glu Asn Gly Pro Pro Phe Gln Phe Phe Leu Asp Asn Ser 
465                 470                 475                 480 


Ala Ser Lys Asn Trp Asn Ile Glu Glu Lys Asp Gly Lys Thr Ala Ile 
                485                 490                 495     


Leu Arg Gln Arg Gln Asn Leu Asp Tyr Asn Tyr Tyr Ser Val Pro Ile 
            500                 505                 510         


Gln Ile Lys Asp Arg His Gly Leu Val Ala Thr His Met Leu Thr Val 
        515                 520                 525             


Arg Val Cys Asp Cys Ser Thr Pro Ser Glu Cys Arg Met Lys Asp Lys 
    530                 535                 540                 


Ser Thr Arg Asp Val Arg Pro Asn Val Ile Leu Gly Arg 
545                 550                 555         


<210>  2368
<211>  418
<212>  PRT
<213>  Homo Sapiens

<400>  2368

Arg His Leu Asp Ala Leu Ala Gly Gly Ala Gly Pro Asn His Gly Asn 
1               5                   10                  15      


Phe Leu Asp Asn Asp Gln Trp Leu Ser Thr Val Ser Gln Tyr Asp Arg 
            20                  25                  30          


Asp Lys Tyr Trp Asn Arg Phe Arg Asp Asp Asp Tyr Phe Arg Asn Trp 
        35                  40                  45              


Asn Pro Asn Lys Pro Phe Asp Lys Ala Leu Asp Pro Ser Lys Asp Pro 
    50                  55                  60                  


Cys Leu Lys Val Lys Cys Ser Pro His Lys Val Cys Val Thr Gln Asp 
65                  70                  75                  80  


Tyr Gln Thr Ala Leu Cys Val Ser Arg Lys His Leu Leu Pro Arg Gln 
                85                  90                  95      


Lys Lys Gly Asn Val Ala Gln Lys His Trp Val Gly Pro Ser Asn Leu 
            100                 105                 110         


Val Lys Cys Lys Pro Cys Pro Val Ala Gln Ser Ala Met Val Cys Gly 
        115                 120                 125             


Ser Asp Gly His Ser Tyr Thr Ser Lys Cys Lys Leu Glu Phe His Ala 
    130                 135                 140                 


Cys Ser Thr Gly Lys Ser Leu Ala Thr Leu Cys Asp Gly Pro Cys Pro 
145                 150                 155                 160 


Cys Leu Pro Glu Pro Glu Pro Pro Lys His Lys Ala Glu Arg Ser Ala 
                165                 170                 175     


Cys Thr Asp Lys Glu Leu Arg Asn Leu Ala Ser Arg Leu Lys Asp Trp 
            180                 185                 190         


Phe Gly Ala Leu His Glu Asp Ala Asn Arg Val Ile Lys Pro Thr Ser 
        195                 200                 205             


Ser Asn Thr Ala Gln Gly Arg Phe Asp Thr Ser Ile Leu Pro Ile Cys 
    210                 215                 220                 


Lys Asp Ser Leu Gly Trp Met Phe Asn Lys Leu Asp Met Asn Tyr Asp 
225                 230                 235                 240 


Leu Leu Leu Asp Pro Ser Glu Ile Asn Ala Ile Tyr Leu Asp Lys Tyr 
                245                 250                 255     


Glu Pro Cys Ile Lys Pro Leu Phe Asn Ser Cys Asp Ser Phe Lys Asp 
            260                 265                 270         


Gly Lys Leu Ser Asn Asn Glu Trp Cys Tyr Cys Phe Gln Lys Pro Gly 
        275                 280                 285             


Gly Leu Pro Cys Gln Asn Glu Met Asn Arg Ile Gln Lys Leu Ser Lys 
    290                 295                 300                 


Gly Lys Ser Leu Leu Gly Ala Phe Ile Pro Arg Cys Asn Glu Glu Gly 
305                 310                 315                 320 


Tyr Tyr Lys Ala Thr Gln Cys His Gly Ser Thr Gly Gln Cys Trp Cys 
                325                 330                 335     


Val Asp Lys Tyr Gly Asn Glu Leu Ala Gly Ser Arg Lys Gln Gly Ala 
            340                 345                 350         


Val Ser Cys Glu Glu Glu Gln Glu Thr Ser Gly Asp Phe Gly Ser Gly 
        355                 360                 365             


Gly Ser Val Val Leu Leu Asp Asp Leu Glu Tyr Glu Arg Glu Leu Gly 
    370                 375                 380                 


Pro Lys Asp Lys Glu Gly Lys Leu Arg Val His Thr Arg Ala Val Thr 
385                 390                 395                 400 


Glu Asp Asp Glu Asp Glu Asp Asp Asp Lys Glu Asp Glu Val Gly Tyr 
                405                 410                 415     


Ile Trp 
        


<210>  2369
<211>  290
<212>  PRT
<213>  Homo Sapiens

<400>  2369

Leu Glu Asp Cys Ala Gln Glu Gln Met Arg Leu Arg Ala Gln Val Arg 
1               5                   10                  15      


Leu Leu Glu Thr Arg Val Lys Gln Gln Gln Val Lys Ile Lys Gln Leu 
            20                  25                  30          


Leu Gln Glu Asn Glu Val Gln Phe Leu Asp Lys Gly Asp Glu Asn Thr 
        35                  40                  45              


Val Ile Asp Leu Gly Ser Lys Arg Gln Tyr Ala Asp Cys Ser Glu Ile 
    50                  55                  60                  


Phe Asn Asp Gly Tyr Lys Leu Ser Gly Phe Tyr Lys Ile Lys Pro Leu 
65                  70                  75                  80  


Gln Ser Pro Ala Glu Phe Ser Val Tyr Cys Asp Met Ser Asp Gly Gly 
                85                  90                  95      


Gly Trp Thr Val Ile Gln Arg Arg Ser Asp Gly Ser Glu Asn Phe Asn 
            100                 105                 110         


Arg Gly Trp Lys Asp Tyr Glu Asn Gly Phe Gly Asn Phe Val Gln Lys 
        115                 120                 125             


His Gly Glu Tyr Trp Leu Gly Asn Lys Asn Leu His Phe Leu Thr Thr 
    130                 135                 140                 


Gln Glu Asp Tyr Thr Leu Lys Ile Asp Leu Ala Asp Phe Glu Lys Asn 
145                 150                 155                 160 


Ser Arg Tyr Ala Gln Tyr Lys Asn Phe Lys Val Gly Asp Glu Lys Asn 
                165                 170                 175     


Phe Tyr Glu Leu Asn Ile Gly Glu Tyr Ser Gly Thr Ala Gly Asp Ser 
            180                 185                 190         


Leu Ala Gly Asn Phe His Pro Glu Val Gln Trp Trp Ala Ser His Gln 
        195                 200                 205             


Arg Met Lys Phe Ser Thr Trp Asp Arg Asp His Asp Asn Tyr Glu Gly 
    210                 215                 220                 


Asn Cys Ala Glu Glu Asp Gln Ser Gly Trp Trp Phe Asn Arg Cys His 
225                 230                 235                 240 


Ser Ala Asn Leu Asn Gly Val Tyr Tyr Ser Gly Pro Tyr Thr Ala Lys 
                245                 250                 255     


Thr Asp Asn Gly Ile Val Trp Tyr Thr Trp His Gly Trp Trp Tyr Ser 
            260                 265                 270         


Leu Lys Ser Val Val Met Lys Ile Arg Pro Asn Asp Phe Ile Pro Asn 
        275                 280                 285             


Val Ile 
    290 


<210>  2370
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  2370

Glu Thr Ser Pro Ile Leu Thr Glu Lys Gln Ala Lys Gln Leu Leu Arg 
1               5                   10                  15      


Ser Arg Arg Gln Asp Arg Pro Ser Lys Pro Gly Phe Pro Asp Glu Pro 
            20                  25                  30          


Met Arg Glu Tyr Met His His Leu Leu Ala Leu Glu His Arg Ala Glu 
        35                  40                  45              


Glu Gln Phe Leu Glu His Trp Leu Asn Pro His Cys Lys Pro His Cys 
    50                  55                  60                  


Asp Arg Asn Arg Ile His Pro Val 
65                  70          


<210>  2371
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  2371

Ala Cys Pro Ala Ser Ala Asp Leu Lys His Ser Asp Gly Thr Arg Thr 
1               5                   10                  15      


Cys Ala Lys Leu Tyr Asp Lys Ser Asp Pro Tyr Tyr Glu Asn Cys Cys 
            20                  25                  30          


Gly Gly Ala Glu Leu Ser Leu Glu Ser Gly Ala Asp Leu Pro Tyr Leu 
        35                  40                  45              


Pro Ser Asn Trp Ala Asn Thr Ala Ser Ser Leu Val Val Ala Pro Arg 
    50                  55                  60                  


Cys Glu Leu Thr Val Trp Ser Arg Gln Gly Lys Ala Gly Lys Thr His 
65                  70                  75                  80  


Lys Phe Ser Ala Gly Thr Tyr Pro Arg Leu Glu Glu Tyr Arg Arg Gly 
                85                  90                  95      


Ile Leu Gly Asp Trp Ser Asn Ala Ile Ser Ala Leu Tyr Cys Arg Cys 
            100                 105                 110         


Ser 
    


<210>  2372
<211>  265
<212>  PRT
<213>  Homo Sapiens

<400>  2372

Gly Ala Arg Ala Arg Trp Arg Gly Glu Gly Thr Ser Ala His Leu Arg 
1               5                   10                  15      


Asp Ile Phe Leu Gly Arg Cys Ala Glu Tyr Arg Ala Leu Leu Ser Pro 
            20                  25                  30          


Glu Gln Arg Asn Lys Asn Cys Thr Ala Ile Trp Glu Ala Phe Lys Val 
        35                  40                  45              


Ala Leu Asp Lys Asp Pro Cys Ser Val Leu Pro Ser Asp Tyr Asp Leu 
    50                  55                  60                  


Phe Ile Asn Leu Ser Arg His Ser Ile Pro Arg Asp Lys Ser Leu Phe 
65                  70                  75                  80  


Trp Glu Asn Ser His Leu Leu Val Asn Ser Phe Ala Asp Asn Thr Arg 
                85                  90                  95      


Arg Phe Met Pro Leu Ser Asp Val Leu Tyr Gly Arg Val Ala Asp Phe 
            100                 105                 110         


Leu Ser Trp Cys Arg Gln Lys Asn Asp Ser Gly Leu Asp Tyr Gln Ser 
        115                 120                 125             


Cys Pro Thr Ser Glu Asp Cys Glu Asn Asn Pro Val Asp Ser Phe Trp 
    130                 135                 140                 


Lys Arg Ala Ser Ile Gln Tyr Ser Lys Asp Ser Ser Gly Val Ile His 
145                 150                 155                 160 


Val Met Leu Asn Gly Ser Glu Pro Thr Gly Ala Tyr Pro Ile Lys Gly 
                165                 170                 175     


Phe Phe Ala Asp Tyr Glu Ile Pro Asn Leu Gln Lys Glu Lys Ile Thr 
            180                 185                 190         


Arg Ile Glu Ile Trp Val Met His Glu Ile Gly Gly Pro Asn Val Glu 
        195                 200                 205             


Ser Cys Gly Glu Gly Ser Met Lys Val Leu Glu Lys Arg Leu Lys Asp 
    210                 215                 220                 


Met Gly Phe Gln Tyr Ser Cys Ile Asn Asp Tyr Arg Pro Val Lys Leu 
225                 230                 235                 240 


Leu Gln Cys Val Asp His Ser Thr His Pro Asp Cys Ala Leu Lys Ser 
                245                 250                 255     


Ala Ala Ala Ala Thr Gln Arg Lys Ala 
            260                 265 


<210>  2373
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  2373

Asn Ser Glu Ala Cys Arg Asp Gly Leu Arg Ala Val Met Glu Cys Arg 
1               5                   10                  15      


Asn Val Thr His Leu Leu Gln Gln Glu Leu Thr Glu Ala Gln Lys Gly 
            20                  25                  30          


Phe Gln Asp Val Glu Ala Gln Ala Ala Thr Cys Asn His Thr Val Met 
        35                  40                  45              


Ala Leu Met Ala Ser Leu Asp Ala Glu Lys Ala Gln Gly Gln Lys Lys 
    50                  55                  60                  


Val Glu Glu Leu Glu Gly Glu Ile Thr Thr Leu Asn His Lys Leu Gln 
65                  70                  75                  80  


Asp Ala Ser Ala Glu Val Glu Arg Leu Arg Arg Glu Asn Gln Val Leu 
                85                  90                  95      


Ser Val Arg Ile Ala Asp Lys Lys Tyr Tyr Pro Ser Ser Gln Asp Ser 
            100                 105                 110         


Ser 
    


<210>  2374
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  2374

Glu Glu Glu Leu Arg Ser Lys Ser Lys Ile Cys Ala Asn Val Phe Cys 
1               5                   10                  15      


Gly Ala Gly Arg Glu Cys Ala Val Thr Glu Lys Gly Glu Pro Thr Cys 
            20                  25                  30          


Leu Cys Ile Glu Gln Cys Lys Pro His Lys Arg Pro Val Cys Gly Ser 
        35                  40                  45              


Asn Gly Lys Thr Tyr Leu Asn His Cys Glu Leu His Arg Asp Ala Cys 
    50                  55                  60                  


Leu Thr Gly Ser Lys Ile Gln Val Asp Tyr Asp Gly His Cys Lys Glu 
65                  70                  75                  80  


Lys Lys Ser Val Ser Pro Ser Ala Ser Pro Val Val Cys Tyr Gln Ser 
                85                  90                  95      


Asn Arg Asp Glu Leu Arg Arg Arg Ile Ile Gln Trp Leu Glu Ala Glu 
            100                 105                 110         


Ile Ile Pro Asp Gly Trp Phe Ser Lys Gly Ser Asn Tyr Ser Glu Ile 
        115                 120                 125             


Leu Asp Lys Tyr Phe Lys Asn Phe Asp Asn Gly Asp Ser Arg Leu Asp 
    130                 135                 140                 


Ser Ser Glu Phe Leu Lys Phe Val Glu Gln Asn Glu Thr Ala Ile Asn 
145                 150                 155                 160 


Ile Thr Thr Tyr Pro Asp Gln Glu Asn Asn Lys Leu Leu Arg Gly Leu 
                165                 170                 175     


Cys Val Asp Ala Leu Ile Glu Leu Ser Asp Glu Asn Ala Asp Trp Lys 
            180                 185                 190         


Leu Ser Phe Gln Glu Phe Leu Lys Cys Leu Asn Pro Ser Phe Asn Pro 
        195                 200                 205             


Pro Glu Lys Lys Cys Ala Leu Glu Asp Glu Thr Tyr Ala Asp Gly Ala 
    210                 215                 220                 


Glu Thr Glu Val Asp Cys Asn Arg Cys Val Cys Ala Cys Gly Asn Trp 
225                 230                 235                 240 


Val Cys Thr Ala Met Thr Cys Asp Gly Lys Asn Gln Lys Gly Ala Gln 
                245                 250                 255     


Thr Gln Thr Glu Glu Glu Met Thr Arg Tyr Val Gln Glu Leu Gln Lys 
            260                 265                 270         


His Gln Glu Thr Ala Glu Lys Thr Lys Arg Val Ser Thr Lys Glu Ile 
        275                 280                 285             


<210>  2375
<211>  735
<212>  PRT
<213>  Homo Sapiens

<400>  2375

Leu Arg Pro Ser Arg Val His Asn Ser Glu Glu Asn Thr Met Arg Ala 
1               5                   10                  15      


Leu Thr Leu Lys Asp Ile Leu Asn Gly Thr Phe Ser Tyr Lys Thr Phe 
            20                  25                  30          


Phe Pro Asn Trp Ile Ser Gly Gln Glu Tyr Leu His Gln Ser Ala Asp 
        35                  40                  45              


Asn Asn Ile Val Leu Tyr Asn Ile Glu Thr Gly Gln Ser Tyr Thr Ile 
    50                  55                  60                  


Leu Ser Asn Arg Thr Met Lys Ser Val Asn Ala Ser Asn Tyr Gly Leu 
65                  70                  75                  80  


Ser Pro Asp Arg Gln Phe Val Tyr Leu Glu Ser Asp Tyr Ser Lys Leu 
                85                  90                  95      


Trp Arg Tyr Ser Tyr Thr Ala Thr Tyr Tyr Ile Tyr Asp Leu Ser Asn 
            100                 105                 110         


Gly Glu Phe Val Arg Gly Asn Glu Leu Pro Arg Pro Ile Gln Tyr Leu 
        115                 120                 125             


Cys Trp Ser Pro Val Gly Ser Lys Leu Ala Tyr Val Tyr Gln Asn Asn 
    130                 135                 140                 


Ile Tyr Leu Lys Gln Arg Pro Gly Asp Pro Pro Phe Gln Ile Thr Phe 
145                 150                 155                 160 


Asn Gly Arg Glu Asn Lys Ile Phe Asn Gly Ile Pro Asp Trp Val Tyr 
                165                 170                 175     


Glu Glu Glu Met Leu Ala Thr Lys Tyr Ala Leu Trp Trp Ser Pro Asn 
            180                 185                 190         


Gly Lys Phe Leu Ala Tyr Ala Glu Phe Asn Asp Thr Asp Ile Pro Val 
        195                 200                 205             


Ile Ala Tyr Ser Tyr Tyr Gly Asp Glu Gln Tyr Pro Arg Thr Ile Asn 
    210                 215                 220                 


Ile Pro Tyr Pro Lys Ala Gly Ala Lys Asn Pro Val Val Arg Ile Phe 
225                 230                 235                 240 


Ile Ile Asp Thr Thr Tyr Pro Ala Tyr Val Gly Pro Gln Glu Val Pro 
                245                 250                 255     


Val Pro Ala Met Ile Ala Ser Ser Asp Tyr Tyr Phe Ser Trp Leu Thr 
            260                 265                 270         


Trp Val Thr Asp Glu Arg Val Cys Leu Gln Trp Leu Lys Arg Val Gln 
        275                 280                 285             


Asn Val Ser Val Leu Ser Ile Cys Asp Phe Arg Glu Asp Trp Gln Thr 
    290                 295                 300                 


Trp Asp Cys Pro Lys Thr Gln Glu His Ile Glu Glu Ser Arg Thr Gly 
305                 310                 315                 320 


Trp Ala Gly Gly Phe Phe Val Ser Thr Pro Val Phe Ser Tyr Asp Ala 
                325                 330                 335     


Ile Ser Tyr Tyr Lys Ile Phe Ser Asp Lys Asp Gly Tyr Lys His Ile 
            340                 345                 350         


His Tyr Ile Lys Asp Thr Val Glu Asn Ala Ile Gln Ile Thr Ser Gly 
        355                 360                 365             


Lys Trp Glu Ala Ile Asn Ile Phe Arg Val Thr Gln Asp Ser Leu Phe 
    370                 375                 380                 


Tyr Ser Ser Asn Glu Phe Glu Glu Tyr Pro Gly Arg Arg Asn Ile Tyr 
385                 390                 395                 400 


Arg Ile Ser Ile Gly Ser Tyr Pro Pro Ser Lys Lys Cys Val Thr Cys 
                405                 410                 415     


His Leu Arg Lys Glu Arg Cys Gln Tyr Tyr Thr Ala Ser Phe Ser Asp 
            420                 425                 430         


Tyr Ala Lys Tyr Tyr Ala Leu Val Cys Tyr Gly Pro Gly Ile Pro Ile 
        435                 440                 445             


Ser Thr Leu His Asp Gly Arg Thr Asp Gln Glu Ile Lys Ile Leu Glu 
    450                 455                 460                 


Glu Asn Lys Glu Leu Glu Asn Ala Leu Lys Asn Ile Gln Leu Pro Lys 
465                 470                 475                 480 


Glu Glu Ile Lys Lys Leu Glu Val Asp Glu Ile Thr Leu Trp Tyr Lys 
                485                 490                 495     


Met Ile Leu Pro Pro Gln Phe Asp Arg Ser Lys Lys Tyr Pro Leu Leu 
            500                 505                 510         


Ile Gln Val Tyr Gly Gly Pro Cys Ser Gln Ser Val Arg Ser Val Phe 
        515                 520                 525             


Ala Val Asn Trp Ile Ser Tyr Leu Ala Ser Lys Glu Gly Met Val Ile 
    530                 535                 540                 


Ala Leu Val Asp Gly Arg Gly Thr Ala Phe Gln Gly Asp Lys Leu Leu 
545                 550                 555                 560 


Tyr Ala Val Tyr Arg Lys Leu Gly Val Tyr Glu Val Glu Asp Gln Ile 
                565                 570                 575     


Thr Ala Val Arg Lys Phe Ile Glu Met Gly Phe Ile Asp Glu Lys Arg 
            580                 585                 590         


Ile Ala Ile Trp Gly Trp Ser Tyr Gly Gly Tyr Val Ser Ser Leu Ala 
        595                 600                 605             


Leu Ala Ser Gly Thr Gly Leu Phe Lys Cys Gly Ile Ala Val Ala Pro 
    610                 615                 620                 


Val Ser Ser Trp Glu Tyr Tyr Ala Ser Val Tyr Thr Glu Arg Phe Met 
625                 630                 635                 640 


Gly Leu Pro Thr Lys Asp Asp Asn Leu Glu His Tyr Lys Asn Ser Thr 
                645                 650                 655     


Val Met Ala Arg Ala Glu Tyr Phe Arg Asn Val Asp Tyr Leu Leu Ile 
            660                 665                 670         


His Gly Thr Ala Asp Asp Asn Val His Phe Gln Asn Ser Ala Gln Ile 
        675                 680                 685             


Ala Lys Ala Leu Val Asn Ala Gln Val Asp Phe Gln Ala Met Trp Tyr 
    690                 695                 700                 


Ser Asp Gln Asn His Gly Leu Ser Gly Leu Ser Thr Asn His Leu Tyr 
705                 710                 715                 720 


Thr His Met Thr His Phe Leu Lys Gln Cys Phe Ser Leu Ser Asp 
                725                 730                 735 


<210>  2376
<211>  657
<212>  PRT
<213>  Homo Sapiens

<400>  2376

His Lys Leu Val Cys Tyr Phe Thr Asn Trp Ala His Ser Arg Pro Gly 
1               5                   10                  15      


Pro Ala Ser Ile Leu Pro His Asp Leu Asp Pro Phe Leu Cys Thr His 
            20                  25                  30          


Leu Ile Phe Ala Phe Ala Ser Met Asn Asn Asn Gln Ile Val Ala Lys 
        35                  40                  45              


Asp Leu Gln Asp Glu Lys Ile Leu Tyr Pro Glu Phe Asn Lys Leu Lys 
    50                  55                  60                  


Glu Arg Asn Arg Glu Leu Lys Thr Leu Leu Ser Ile Gly Gly Trp Asn 
65                  70                  75                  80  


Phe Gly Thr Ser Arg Phe Thr Thr Met Leu Ser Thr Phe Ala Asn Arg 
                85                  90                  95      


Glu Lys Phe Ile Ala Ser Val Ile Ser Leu Leu Arg Thr His Asp Phe 
            100                 105                 110         


Asp Gly Leu Asp Leu Phe Phe Leu Tyr Pro Gly Leu Arg Gly Ser Pro 
        115                 120                 125             


Met His Asp Arg Trp Thr Phe Leu Phe Leu Ile Glu Glu Leu Leu Phe 
    130                 135                 140                 


Ala Phe Arg Lys Glu Ala Leu Leu Thr Met Arg Pro Arg Leu Leu Leu 
145                 150                 155                 160 


Ser Ala Ala Val Ser Gly Val Pro His Ile Val Gln Thr Ser Tyr Asp 
                165                 170                 175     


Val Arg Phe Leu Gly Arg Leu Leu Asp Phe Ile Asn Val Leu Ser Tyr 
            180                 185                 190         


Asp Leu His Gly Ser Trp Glu Arg Phe Thr Gly His Asn Ser Pro Leu 
        195                 200                 205             


Phe Ser Leu Pro Glu Asp Pro Lys Ser Ser Ala Tyr Ala Met Asn Tyr 
    210                 215                 220                 


Trp Arg Lys Leu Gly Ala Pro Ser Glu Lys Leu Ile Met Gly Ile Pro 
225                 230                 235                 240 


Thr Tyr Gly Arg Thr Phe Arg Leu Leu Lys Ala Ser Lys Asn Gly Leu 
                245                 250                 255     


Gln Ala Arg Ala Ile Gly Pro Ala Ser Pro Gly Lys Tyr Thr Lys Gln 
            260                 265                 270         


Glu Gly Phe Leu Ala Tyr Phe Glu Ile Cys Ser Phe Val Trp Gly Ala 
        275                 280                 285             


Lys Lys His Trp Ile Asp Tyr Gln Tyr Val Pro Tyr Ala Asn Lys Gly 
    290                 295                 300                 


Lys Glu Trp Val Gly Tyr Asp Asn Ala Ile Ser Phe Ser Tyr Lys Ala 
305                 310                 315                 320 


Trp Phe Ile Arg Arg Glu His Phe Gly Gly Ala Met Val Trp Thr Leu 
                325                 330                 335     


Asp Met Asp Asp Val Arg Gly Thr Phe Cys Gly Thr Gly Pro Phe Pro 
            340                 345                 350         


Leu Val Tyr Val Leu Asn Asp Ile Leu Val Arg Ala Glu Phe Ser Ser 
        355                 360                 365             


Thr Ser Leu Pro Gln Phe Trp Leu Ser Ser Ala Val Asn Ser Ser Ser 
    370                 375                 380                 


Thr Asp Pro Glu Arg Leu Ala Val Thr Thr Ala Trp Thr Thr Asp Ser 
385                 390                 395                 400 


Lys Ile Leu Pro Pro Gly Gly Glu Ala Gly Val Thr Glu Ile His Gly 
                405                 410                 415     


Lys Cys Glu Asn Met Thr Ile Thr Pro Arg Gly Thr Thr Val Thr Pro 
            420                 425                 430         


Thr Lys Glu Thr Val Ser Leu Gly Lys His Thr Val Ala Leu Gly Glu 
        435                 440                 445             


Lys Thr Glu Ile Thr Gly Ala Met Thr Met Thr Ser Val Gly His Gln 
    450                 455                 460                 


Ser Met Thr Pro Gly Glu Lys Ala Leu Thr Pro Val Gly His Gln Ser 
465                 470                 475                 480 


Val Thr Thr Gly Gln Lys Thr Leu Thr Ser Val Gly Tyr Gln Ser Val 
                485                 490                 495     


Thr Pro Gly Glu Lys Thr Leu Thr Pro Val Gly His Gln Ser Val Thr 
            500                 505                 510         


Pro Val Ser His Gln Ser Val Ser Pro Gly Gly Thr Thr Met Thr Pro 
        515                 520                 525             


Val His Phe Gln Thr Glu Thr Leu Arg Gln Asn Thr Val Ala Pro Arg 
    530                 535                 540                 


Arg Lys Ala Val Ala Arg Glu Lys Val Thr Val Pro Ser Arg Asn Ile 
545                 550                 555                 560 


Ser Val Thr Pro Glu Gly Gln Thr Met Pro Leu Arg Gly Glu Asn Leu 
                565                 570                 575     


Thr Ser Glu Val Gly Thr His Pro Arg Met Gly Asn Leu Gly Leu Gln 
            580                 585                 590         


Met Glu Ala Glu Asn Arg Met Met Leu Ser Ser Ser Pro Val Ile Gln 
        595                 600                 605             


Leu Pro Glu Gln Thr Pro Leu Ala Phe Asp Asn Arg Phe Val Pro Ile 
    610                 615                 620                 


Tyr Gly Asn His Ser Ser Val Asn Ser Val Thr Pro Gln Thr Ser Pro 
625                 630                 635                 640 


Leu Ser Leu Lys Lys Glu Ile Pro Glu Asn Ser Ala Val Asp Glu Glu 
                645                 650                 655     


Ala 
    


<210>  2377
<211>  166
<212>  PRT
<213>  Homo Sapiens

<400>  2377

Ser Lys Pro Ile Asp Val Ser Arg Leu Asp Leu Arg Ile Gly Cys Ile 
1               5                   10                  15      


Ile Thr Ala Arg Lys His Pro Asp Ala Asp Ser Leu Tyr Val Glu Glu 
            20                  25                  30          


Val Asp Val Gly Glu Ile Ala Pro Arg Thr Val Val Ser Gly Leu Val 
        35                  40                  45              


Asn His Val Pro Leu Glu Gln Met Gln Asn Arg Met Val Ile Leu Leu 
    50                  55                  60                  


Cys Asn Leu Lys Pro Ala Lys Met Arg Gly Val Leu Ser Gln Ala Met 
65                  70                  75                  80  


Val Met Cys Ala Ser Ser Pro Glu Lys Ile Glu Ile Leu Ala Pro Pro 
                85                  90                  95      


Asn Gly Ser Val Pro Gly Asp Arg Ile Thr Phe Asp Ala Phe Pro Gly 
            100                 105                 110         


Glu Pro Asp Lys Glu Leu Asn Pro Lys Lys Lys Ile Trp Glu Gln Ile 
        115                 120                 125             


Gln Pro Asp Leu His Thr Asn Asp Glu Cys Val Ala Thr Tyr Lys Gly 
    130                 135                 140                 


Val Pro Phe Glu Val Lys Gly Lys Gly Val Cys Arg Ala Gln Thr Met 
145                 150                 155                 160 


Ser Asn Ser Gly Ile Lys 
                165     


<210>  2378
<211>  532
<212>  PRT
<213>  Homo Sapiens

<400>  2378

Met Pro His Val Ile Arg Ile Gly Gly Ile Phe Glu Tyr Ala Asp Gly 
1               5                   10                  15      


Pro Asn Ala Gln Val Met Asn Ala Glu Glu His Ala Phe Arg Phe Ser 
            20                  25                  30          


Ala Asn Ile Ile Asn Arg Asn Arg Thr Leu Leu Pro Asn Thr Thr Leu 
        35                  40                  45              


Thr Tyr Asp Ile Gln Arg Ile His Phe His Asp Ser Phe Glu Ala Thr 
    50                  55                  60                  


Lys Lys Ala Cys Asp Gln Leu Ala Leu Gly Val Val Ala Ile Phe Gly 
65                  70                  75                  80  


Pro Ser Gln Gly Ser Cys Thr Asn Ala Val Gln Ser Ile Cys Asn Ala 
                85                  90                  95      


Leu Glu Val Pro His Ile Gln Leu Arg Trp Lys His His Pro Leu Asp 
            100                 105                 110         


Asn Lys Asp Thr Phe Tyr Val Asn Leu Tyr Pro Asp Tyr Ala Ser Leu 
        115                 120                 125             


Ser His Ala Ile Leu Asp Leu Val Gln Tyr Leu Lys Trp Arg Ser Ala 
    130                 135                 140                 


Thr Val Val Tyr Asp Asp Ser Thr Gly Leu Ile Arg Leu Gln Glu Leu 
145                 150                 155                 160 


Ile Met Ala Pro Ser Arg Tyr Asn Ile Arg Leu Lys Ile Arg Gln Leu 
                165                 170                 175     


Pro Ile Asp Ser Asp Asp Ser Arg Pro Leu Leu Lys Glu Met Lys Arg 
            180                 185                 190         


Gly Arg Glu Phe Arg Ile Ile Phe Asp Cys Ser His Thr Met Ala Ala 
        195                 200                 205             


Gln Ile Leu Lys Gln Ala Met Ala Met Gly Met Met Thr Glu Tyr Tyr 
    210                 215                 220                 


His Phe Ile Phe Thr Thr Leu Asp Leu Tyr Ala Leu Asp Leu Glu Pro 
225                 230                 235                 240 


Tyr Arg Tyr Ser Gly Val Asn Leu Thr Gly Phe Arg Ile Leu Asn Val 
                245                 250                 255     


Asp Asn Pro His Val Ser Ala Ile Val Glu Lys Trp Ser Met Glu Arg 
            260                 265                 270         


Leu Gln Ala Ala Pro Arg Ser Glu Ser Gly Leu Leu Asp Gly Val Met 
        275                 280                 285             


Met Thr Asp Ala Ala Leu Leu Tyr Asp Ala Val His Ile Val Ser Val 
    290                 295                 300                 


Cys Tyr Gln Arg Ala Pro Gln Met Thr Val Asn Ser Leu Gln Cys His 
305                 310                 315                 320 


Arg His Lys Ala Trp Arg Phe Gly Gly Arg Phe Met Asn Phe Ile Lys 
                325                 330                 335     


Glu Ala Gln Trp Glu Gly Leu Thr Gly Arg Ile Val Phe Asn Lys Thr 
            340                 345                 350         


Ser Gly Leu Arg Thr Asp Phe Asp Leu Asp Ile Ile Ser Leu Lys Glu 
        355                 360                 365             


Asp Gly Leu Glu Lys Val Gly Val Trp Ser Pro Ala Asp Gly Leu Asn 
    370                 375                 380                 


Ile Thr Glu Val Ala Lys Gly Arg Gly Pro Asn Val Thr Asp Ser Leu 
385                 390                 395                 400 


Thr Asn Arg Ser Leu Ile Val Thr Thr Val Leu Glu Glu Pro Phe Val 
                405                 410                 415     


Met Phe Arg Lys Ser Asp Arg Thr Leu Tyr Gly Asn Asp Arg Phe Glu 
            420                 425                 430         


Gly Tyr Cys Ile Asp Leu Leu Lys Glu Leu Ala His Ile Leu Gly Phe 
        435                 440                 445             


Ser Tyr Glu Ile Arg Leu Val Glu Asp Gly Lys Tyr Gly Ala Gln Asp 
    450                 455                 460                 


Asp Lys Gly Gln Trp Asn Gly Met Val Lys Glu Leu Ile Asp His Lys 
465                 470                 475                 480 


Ala Asp Leu Ala Val Ala Pro Leu Thr Ile Thr His Val Arg Glu Lys 
                485                 490                 495     


Ala Ile Asp Phe Ser Lys Pro Phe Met Thr Leu Gly Val Ser Ile Leu 
            500                 505                 510         


Tyr Arg Lys Pro Asn Gly Thr Asn Pro Ser Val Phe Ser Phe Leu Asn 
        515                 520                 525             


Pro Leu Ser Pro 
    530         


<210>  2379
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  2379

Gln Glu Gln Gly Ala Arg Ser Pro Ser Glu Glu Pro Pro Glu Glu Glu 
1               5                   10                  15      


Ile Pro Lys Glu Asp Gly Ile Leu Val Leu Ser Arg His Thr Leu Gly 
            20                  25                  30          


Leu Ala Leu Arg Glu His Pro Ala Leu Leu Val Glu Phe Tyr Ala Pro 
        35                  40                  45              


Trp Cys Gly His Cys Gln Ala Leu Ala Pro Glu Tyr Ser Lys Ala Ala 
    50                  55                  60                  


Ala Val Leu Ala Ala Glu Ser Met Val Val Thr Leu Ala Lys Val Asp 
65                  70                  75                  80  


Gly Pro Ala Gln Arg Glu Leu Ala Glu Glu Phe Gly Val Thr Glu Tyr 
                85                  90                  95      


Pro Thr Leu Lys Phe Phe Arg Asn Gly Asn Arg Thr His Pro Glu Glu 
            100                 105                 110         


Tyr Thr Gly Pro Arg Asp Ala Glu Gly Ile Ala Glu Trp Leu Arg Arg 
        115                 120                 125             


Arg Val Gly Pro Ser Ala Met Arg Leu Glu Asp Glu Ala Ala Ala Gln 
    130                 135                 140                 


Ala Leu Ile Gly Gly Arg Asp Leu Val Val Ile Gly Phe Phe Gln Asp 
145                 150                 155                 160 


Leu Gln Asp Glu Asp Val Ala Thr Phe Leu Ala Leu Ala Gln Asp Ala 
                165                 170                 175     


Leu Asp Met Thr Phe Gly Leu Thr Asp Arg Pro Arg Leu Phe Gln Gln 
            180                 185                 190         


Phe Gly Leu Thr Lys Asp Thr Val Val Leu Phe Lys Lys Phe Asp Glu 
        195                 200                 205             


Gly Arg Ala Asp Phe Pro Val Asp Glu Glu Leu Gly Leu Asp Leu Gly 
    210                 215                 220                 


Asp Leu Ser Arg Phe Leu Val Thr His Ser Met Arg Leu Val Thr Glu 
225                 230                 235                 240 


Phe Asn Ser Gln Thr Ser Ala Lys Ile Phe Ala Ala Arg Ile Leu Asn 
                245                 250                 255     


His Leu Leu Leu Phe Val Asn Gln Thr Leu Ala Ala His Arg Glu Leu 
            260                 265                 270         


Leu Ala Gly Phe Gly Glu Ala Ala Pro Arg Phe Arg Gly Gln Val Leu 
        275                 280                 285             


Phe Val Val Val Asp Val Ala Ala Asp Asn Glu His Val Leu Gln Tyr 
    290                 295                 300                 


Phe Gly Leu Lys Ala Glu Ala Ala Pro Thr Leu Arg Leu Val Asn Leu 
305                 310                 315                 320 


Glu Thr Thr Lys Lys Tyr Ala Pro Val Asp Gly Gly Pro Val Thr Ala 
                325                 330                 335     


Ala Ser Ile Thr Ala Phe Cys His Ala Val Leu Asn Gly Gln Val Lys 
            340                 345                 350         


Pro Tyr Leu Leu Ser Gln Glu Ile Pro Pro Asp Trp Asp Gln Arg Pro 
        355                 360                 365             


Val Lys Thr Leu Val Gly Lys Asn Phe Glu Gln Val Ala Phe Asp Glu 
    370                 375                 380                 


Thr Lys Asn Val Phe Val Lys Phe Tyr Ala Pro Trp Cys Thr His Cys 
385                 390                 395                 400 


Lys Glu Met Ala Pro Ala Trp Glu Ala Leu Ala Glu Lys Tyr Gln Asp 
                405                 410                 415     


His Glu Asp Ile Ile Ile Ala Glu Leu Asp Ala Thr Ala Asn Glu Leu 
            420                 425                 430         


Asp Ala Phe Ala Val His Gly Phe Pro Thr Leu Lys Tyr Phe Pro Ala 
        435                 440                 445             


Gly Pro Gly Arg Lys Val Ile Glu Tyr Lys Ser Thr Arg Asp Leu Glu 
    450                 455                 460                 


Thr Phe Ser Lys Phe Leu Asp Asn Gly Gly Val Leu Pro Thr Glu Glu 
465                 470                 475                 480 


Pro Pro Glu Glu Pro Ala Ala Pro Phe Pro Glu Pro Pro Ala Asn Ser 
                485                 490                 495     


Thr Met Gly Ser 
            500 


<210>  2380
<211>  420
<212>  PRT
<213>  Homo Sapiens

<400>  2380

Phe Asp Trp Gln Tyr Ile Asn Pro Val Ala His Met Lys Ser Ser Ala 
1               5                   10                  15      


Trp Val Asn Lys Ile Gln Val Leu Met Ala Ala Ala Ser Phe Gly Gln 
            20                  25                  30          


Thr Lys Ile Pro Arg Gly Asn Gly Pro Tyr Ser Val Gly Cys Thr Asp 
        35                  40                  45              


Leu Met Phe Asp His Thr Asn Lys Gly Thr Phe Leu Arg Leu Tyr Tyr 
    50                  55                  60                  


Pro Ser Gln Asp Asn Asp Arg Leu Asp Thr Leu Trp Ile Pro Asn Lys 
65                  70                  75                  80  


Glu Tyr Phe Trp Gly Leu Ser Lys Phe Leu Gly Thr His Trp Leu Met 
                85                  90                  95      


Gly Asn Ile Leu Arg Leu Leu Phe Gly Ser Met Thr Thr Pro Ala Asn 
            100                 105                 110         


Trp Asn Ser Pro Leu Arg Pro Gly Glu Lys Tyr Pro Leu Val Val Phe 
        115                 120                 125             


Ser His Gly Leu Gly Ala Phe Arg Thr Leu Tyr Ser Ala Ile Gly Ile 
    130                 135                 140                 


Asp Leu Ala Ser His Gly Phe Ile Val Ala Ala Val Glu His Arg Asp 
145                 150                 155                 160 


Arg Ser Ala Ser Ala Thr Tyr Tyr Phe Lys Asp Gln Ser Ala Ala Glu 
                165                 170                 175     


Ile Gly Asp Lys Ser Trp Leu Tyr Leu Arg Thr Leu Lys Gln Glu Glu 
            180                 185                 190         


Glu Thr His Ile Arg Asn Glu Gln Val Arg Gln Arg Ala Lys Glu Cys 
        195                 200                 205             


Ser Gln Ala Leu Ser Leu Ile Leu Asp Ile Asp His Gly Lys Pro Val 
    210                 215                 220                 


Lys Asn Ala Leu Asp Leu Lys Phe Asp Met Glu Gln Leu Lys Asp Ser 
225                 230                 235                 240 


Ile Asp Arg Glu Lys Ile Ala Val Ile Gly His Ser Phe Gly Gly Ala 
                245                 250                 255     


Thr Val Ile Gln Thr Leu Ser Glu Asp Gln Arg Phe Arg Cys Gly Ile 
            260                 265                 270         


Ala Leu Asp Ala Trp Met Phe Pro Leu Gly Asp Glu Val Tyr Ser Arg 
        275                 280                 285             


Ile Pro Gln Pro Leu Phe Phe Ile Asn Ser Glu Tyr Phe Gln Tyr Pro 
    290                 295                 300                 


Ala Asn Ile Ile Lys Met Lys Lys Cys Tyr Ser Pro Asp Lys Glu Arg 
305                 310                 315                 320 


Lys Met Ile Thr Ile Arg Gly Ser Val His Gln Asn Phe Ala Asp Phe 
                325                 330                 335     


Thr Phe Ala Thr Gly Lys Ile Ile Gly His Met Leu Lys Leu Lys Gly 
            340                 345                 350         


Asp Ile Asp Ser Asn Ala Ala Ile Asp Leu Ser Asn Lys Ala Ser Leu 
        355                 360                 365             


Ala Phe Leu Gln Lys His Leu Gly Leu His Lys Asp Phe Asp Gln Trp 
    370                 375                 380                 


Asp Cys Leu Ile Glu Gly Asp Asp Glu Asn Leu Ile Pro Gly Thr Asn 
385                 390                 395                 400 


Ile Asn Thr Thr Asn Gln His Ile Met Leu Gln Asn Ser Ser Gly Ile 
                405                 410                 415     


Glu Lys Tyr Asn 
            420 


<210>  2381
<211>  132
<212>  PRT
<213>  Homo Sapiens

<400>  2381

Val Leu Leu Thr Lys Gly Glu Ile Arg Cys Tyr Cys Asp Ala Ala His 
1               5                   10                  15      


Cys Val Ala Thr Gly Tyr Met Cys Lys Ser Glu Leu Ser Ala Cys Phe 
            20                  25                  30          


Ser Arg Leu Leu Asp Pro Gln Asn Ser Asn Ser Pro Leu Thr His Gly 
        35                  40                  45              


Cys Leu Asp Ser Leu Ala Ser Thr Thr Asp Ile Cys Gln Ala Lys Gln 
    50                  55                  60                  


Ala Arg Asn His Ser Gly Thr Thr Ile Pro Thr Leu Glu Cys Cys His 
65                  70                  75                  80  


Glu Asp Met Cys Asn Tyr Arg Gly Leu His Asp Val Leu Ser Pro Pro 
                85                  90                  95      


Arg Gly Glu Ala Ser Gly Gln Gly Asn Arg Tyr Gln His Asp Gly Ser 
            100                 105                 110         


Arg Asn Leu Ile Thr Lys Val Gln Glu Leu Thr Ser Ser Lys Glu Leu 
        115                 120                 125             


Trp Phe Arg Ala 
    130         


<210>  2382
<211>  234
<212>  PRT
<213>  Homo Sapiens

<400>  2382

Trp Glu Thr Glu Glu Arg Pro Arg Thr Arg Glu Glu Glu Cys His Phe 
1               5                   10                  15      


Tyr Ala Gly Gly Gln Val Tyr Pro Gly Glu Ala Ser Arg Val Ser Val 
            20                  25                  30          


Ala Asp His Ser Leu His Leu Ser Lys Ala Lys Ile Ser Lys Pro Ala 
        35                  40                  45              


Pro Tyr Trp Glu Gly Thr Ala Val Ile Asp Gly Glu Phe Lys Glu Leu 
    50                  55                  60                  


Lys Leu Thr Asp Tyr Arg Gly Lys Tyr Leu Val Phe Phe Phe Tyr Pro 
65                  70                  75                  80  


Leu Asp Phe Thr Phe Val Cys Pro Thr Glu Ile Ile Ala Phe Gly Asp 
                85                  90                  95      


Arg Leu Glu Glu Phe Arg Ser Ile Asn Thr Glu Val Val Ala Cys Ser 
            100                 105                 110         


Val Asp Ser Gln Phe Thr His Leu Ala Trp Ile Asn Thr Pro Arg Arg 
        115                 120                 125             


Gln Gly Gly Leu Gly Pro Ile Arg Ile Pro Leu Leu Ser Asp Leu Thr 
    130                 135                 140                 


His Gln Ile Ser Lys Asp Tyr Gly Val Tyr Leu Glu Asp Ser Gly His 
145                 150                 155                 160 


Thr Leu Arg Gly Leu Phe Ile Ile Asp Asp Lys Gly Ile Leu Arg Gln 
                165                 170                 175     


Ile Thr Leu Asn Asp Leu Pro Val Gly Arg Ser Val Asp Glu Thr Leu 
            180                 185                 190         


Arg Leu Val Gln Ala Phe Gln Tyr Thr Asp Lys His Gly Glu Val Cys 
        195                 200                 205             


Pro Ala Gly Trp Lys Pro Gly Ser Glu Thr Ile Ile Pro Asp Pro Ala 
    210                 215                 220                 


Gly Lys Leu Lys Tyr Phe Asp Lys Leu Asn 
225                 230                 


<210>  2383
<211>  473
<212>  PRT
<213>  Homo Sapiens

<400>  2383

Gly Val Asn Ala Asp Val Glu Lys His Leu Glu Leu Gly Lys Lys Leu 
1               5                   10                  15      


Leu Ala Ala Gly Gln Leu Ala Asp Ala Leu Ser Gln Phe His Ala Ala 
            20                  25                  30          


Val Asp Gly Asp Pro Asp Asn Tyr Ile Ala Tyr Tyr Arg Arg Ala Thr 
        35                  40                  45              


Val Phe Leu Ala Met Gly Lys Ser Lys Ala Ala Leu Pro Asp Leu Thr 
    50                  55                  60                  


Lys Val Ile Gln Leu Lys Met Asp Phe Thr Ala Ala Arg Leu Gln Arg 
65                  70                  75                  80  


Gly His Leu Leu Leu Lys Gln Gly Lys Leu Asp Glu Ala Glu Asp Asp 
                85                  90                  95      


Phe Lys Lys Val Leu Lys Ser Asn Pro Ser Glu Asn Glu Glu Lys Glu 
            100                 105                 110         


Ala Gln Ser Gln Leu Ile Lys Ser Asp Glu Met Gln Arg Leu Arg Ser 
        115                 120                 125             


Gln Ala Leu Asn Ala Phe Gly Ser Gly Asp Tyr Thr Ala Ala Ile Ala 
    130                 135                 140                 


Phe Leu Asp Lys Ile Leu Glu Val Cys Val Trp Asp Ala Glu Leu Arg 
145                 150                 155                 160 


Glu Leu Arg Ala Glu Cys Phe Ile Lys Glu Gly Glu Pro Arg Lys Ala 
                165                 170                 175     


Ile Ser Asp Leu Lys Ala Ala Ser Lys Leu Lys Asn Asp Asn Thr Glu 
            180                 185                 190         


Ala Phe Tyr Lys Ile Ser Thr Leu Tyr Tyr Gln Leu Gly Asp His Glu 
        195                 200                 205             


Leu Ser Leu Ser Glu Val Arg Glu Cys Leu Lys Leu Asp Gln Asp His 
    210                 215                 220                 


Lys Arg Cys Phe Ala His Tyr Lys Gln Val Lys Lys Leu Asn Lys Leu 
225                 230                 235                 240 


Ile Glu Ser Ala Glu Glu Leu Ile Arg Asp Gly Arg Tyr Thr Asp Ala 
                245                 250                 255     


Thr Ser Lys Tyr Glu Ser Val Met Lys Thr Glu Pro Ser Ile Ala Glu 
            260                 265                 270         


Tyr Thr Val Arg Ser Lys Glu Arg Ile Cys His Cys Phe Ser Lys Asp 
        275                 280                 285             


Glu Lys Pro Val Glu Ala Ile Arg Val Cys Ser Glu Val Leu Gln Met 
    290                 295                 300                 


Glu Pro Asp Asn Val Asn Ala Leu Lys Asp Arg Ala Glu Ala Tyr Leu 
305                 310                 315                 320 


Ile Glu Glu Met Tyr Asp Glu Ala Ile Gln Asp Tyr Glu Thr Ala Gln 
                325                 330                 335     


Glu His Asn Glu Asn Asp Gln Gln Ile Arg Glu Gly Leu Glu Lys Ala 
            340                 345                 350         


Gln Arg Leu Leu Lys Gln Ser Gln Lys Arg Asp Tyr Tyr Lys Ile Leu 
        355                 360                 365             


Gly Val Lys Arg Asn Ala Lys Lys Gln Glu Ile Ile Lys Ala Tyr Arg 
    370                 375                 380                 


Lys Leu Ala Leu Gln Trp His Pro Asp Asn Phe Gln Asn Glu Glu Glu 
385                 390                 395                 400 


Lys Lys Lys Ala Glu Lys Lys Phe Ile Asp Ile Ala Ala Ala Lys Glu 
                405                 410                 415     


Val Leu Ser Asp Pro Glu Met Arg Lys Lys Phe Asp Asp Gly Glu Asp 
            420                 425                 430         


Pro Leu Asp Ala Glu Ser Gln Gln Gly Gly Gly Gly Asn Pro Phe His 
        435                 440                 445             


Arg Ser Trp Asn Ser Trp Gln Gly Phe Asn Pro Phe Ser Ser Gly Gly 
    450                 455                 460                 


Pro Phe Arg Phe Lys Phe His Phe Asn 
465                 470             


<210>  2384
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  2384

Ala Lys Leu Val Cys Tyr Phe Thr Asn Trp Ala Gln Tyr Arg Gln Gly 
1               5                   10                  15      


Glu Ala Arg Phe Leu Pro Lys Asp Leu Asp Pro Ser Leu Cys Thr His 
            20                  25                  30          


Leu Ile Tyr Ala Phe Ala Gly Met Thr Asn His Gln Leu Ser Thr Thr 
        35                  40                  45              


Glu Trp Asn Asp Glu Thr Leu Tyr Gln Glu Phe Asn Gly Leu Lys Lys 
    50                  55                  60                  


Met Asn Pro Lys Leu Lys Thr Leu Leu Ala Ile Gly Gly Trp Asn Phe 
65                  70                  75                  80  


Ser Thr Gln Lys Phe Thr Asp Met Val Ala Thr Ala Asn Asn Arg Gln 
                85                  90                  95      


Thr Phe Val Asn Ser Ala Ile Arg Phe Leu Arg Lys Tyr Ser Phe Asp 
            100                 105                 110         


Gly Leu Asp Leu Asp Trp Glu Tyr Pro Gly Ser Gln Gly Ser Pro Ala 
        115                 120                 125             


Val Asp Lys Glu Arg Phe Thr Thr Leu Val Gln Asp Leu Ala Asn Ala 
    130                 135                 140                 


Phe Gln Gln Glu Ala Gln Thr Ser Gly Lys Glu Arg Leu Leu Leu Ser 
145                 150                 155                 160 


Ala Ala Val Pro Ala Gly Gln Thr Tyr Val Asp Ala Gly Tyr Glu Val 
                165                 170                 175     


Asp Lys Ile Ala Gln Asn Leu Asp Phe Val Asn Leu Met Ala Tyr Asp 
            180                 185                 190         


Phe His Gly Ser Trp Glu Lys Val Thr Gly His Asn Ser Pro Leu Tyr 
        195                 200                 205             


Lys Arg Gln Glu Glu Ser Gly Ala Ala Ala Ser Leu Asn Val Asp Ala 
    210                 215                 220                 


Ala Val Gln Gln Trp Leu Gln Lys Gly Thr Pro Ala Ser Lys Leu Ile 
225                 230                 235                 240 


Leu Gly Met Pro Thr Tyr Gly Arg Ser Phe Thr Leu Ala Ser Ser Ser 
                245                 250                 255     


Asp Thr Arg Val Gly Ala Pro Ala Thr Gly Ser Gly Thr Pro Gly Pro 
            260                 265                 270         


Phe Thr Lys Glu Gly Gly Met Leu Ala Tyr Tyr Glu Val Cys Ser Trp 
        275                 280                 285             


Lys Gly Ala Thr Lys Gln Arg Ile Gln Asp Gln Lys Val Pro Tyr Ile 
    290                 295                 300                 


Phe Arg Asp Asn Gln Trp Val Gly Phe Asp Asp Val Glu Ser Phe Lys 
305                 310                 315                 320 


Thr Lys Val Ser Tyr Leu Lys Gln Lys Gly Leu Gly Gly Ala Met Val 
                325                 330                 335     


Trp Ala Leu Asp Leu Asp Asp Phe Ala Gly Phe Ser Cys Asn Gln Gly 
            340                 345                 350         


Arg Tyr Pro Leu Ile Gln Thr Leu Arg Gln Glu Leu Ser Leu Pro Tyr 
        355                 360                 365             


Leu Pro Ser Gly Thr Pro Glu Leu Glu Val Pro Lys Pro Gly Gln Pro 
    370                 375                 380                 


Ser Glu Pro Glu His Gly Pro Ser Pro Gly Gln Asp Thr Phe Cys Gln 
385                 390                 395                 400 


Gly Lys Ala Asp Gly Leu Tyr Pro Asn Pro Arg Glu Arg Ser Ser Phe 
                405                 410                 415     


Tyr Ser Cys Ala Ala Gly Arg Leu Phe Gln Gln Ser Cys Pro Thr Gly 
            420                 425                 430         


Leu Val Phe Ser Asn Ser Cys Lys Cys Cys Thr Trp Asn 
        435                 440                 445 


<210>  2385
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  2385

Gln His Tyr Leu His Ile Arg Pro Ala Pro Ser Asp Asn Leu Pro Leu 
1               5                   10                  15      


Val Asp Leu Ile Glu His Pro Asp Pro Ile Phe Asp Pro Lys Glu Lys 
            20                  25                  30          


Asp Leu Asn Glu Thr Leu Leu Arg Ser Leu Leu Gly Gly His Tyr Asp 
        35                  40                  45              


Pro Gly Phe Met Ala Thr Ser Pro Pro Glu Asp Arg Pro Gly Gly Gly 
    50                  55                  60                  


Gly Gly Ala Ala Gly Gly Ala Glu Asp Leu Ala Glu Leu Asp Gln Leu 
65                  70                  75                  80  


Leu Arg Gln Arg Pro Ser Gly Ala Met Pro Ser Glu Ile Lys Gly Leu 
                85                  90                  95      


Glu Phe Ser Glu Gly Leu Ala Gln Gly Lys Lys Gln Arg Leu Ser Lys 
            100                 105                 110         


Lys Leu Arg Arg Lys Leu Gln Met Trp Leu Trp Ser Gln Thr Phe Cys 
        115                 120                 125             


Pro Val Leu Tyr Ala Trp Asn Asp Leu Gly Ser Arg Phe Trp Pro Arg 
    130                 135                 140                 


Tyr Val Lys Val Gly Ser Cys Phe Ser Lys Arg Ser Cys Ser Val Pro 
145                 150                 155                 160 


Glu Gly Met Val Cys Lys Pro Ser Lys Ser Val His Leu Thr Val Leu 
                165                 170                 175     


Arg Trp Arg Cys Gln Arg Arg Gly Gly Gln Arg Cys Gly Trp Ile Pro 
            180                 185                 190         


Ile Gln Tyr Pro Ile Ile Ser Glu Cys Lys Cys Ser Cys 
        195                 200                 205 


<210>  2386
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  2386

Gly Ser Gly Cys Pro Leu Leu Glu Asn Val Ile Ser Lys Thr Ile Asn 
1               5                   10                  15      


Pro Gln Val Ser Lys Thr Glu Tyr Lys Glu Leu Leu Gln Glu Phe Ile 
            20                  25                  30          


Asp Asp Asn Ala Thr Thr Asn Ala Ile Asp Glu Leu Lys Glu Cys Phe 
        35                  40                  45              


Leu Asn Gln Thr Asp Glu Thr Leu Ser Asn Val Glu Val Phe Met Gln 
    50                  55                  60                  


Leu Ile Tyr Asp Ser Ser Leu Cys Asp Leu Phe 
65                  70                  75  


<210>  2387
<211>  497
<212>  PRT
<213>  Homo Sapiens

<400>  2387

Leu Pro Val Thr Arg Tyr Gln Asn Asn Glu Ser Glu Asp Ser Glu Glu 
1               5                   10                  15      


Trp Lys Gly His Leu Ala Gln Ala Pro Thr Pro Pro Leu Glu Ser Ser 
            20                  25                  30          


Glu Ser Ser Glu Gly Ser Lys Val Ser Ser Glu Glu Gln Ala Asn Glu 
        35                  40                  45              


Asp Pro Ser Asp Ser Thr Gln Ser Glu Glu Gly Leu Gly Ser Asp Asp 
    50                  55                  60                  


His Gln Tyr Ile Tyr Arg Leu Ala Gly Gly Phe Ser Arg Ser Thr Gly 
65                  70                  75                  80  


Lys Gly Gly Asp Asp Lys Asp Asp Asp Glu Asp Asp Ser Gly Asp Asp 
                85                  90                  95      


Thr Phe Gly Asp Asp Asp Ser Gly Pro Gly Pro Lys Asp Arg Gln Glu 
            100                 105                 110         


Gly Gly Asn Ser Arg Leu Gly Ser Asp Glu Asp Ser Asp Asp Thr Ile 
        115                 120                 125             


Gln Ala Ser Glu Glu Ser Ala Pro Gln Gly Gln Asp Ser Ala Gln Asp 
    130                 135                 140                 


Thr Thr Ser Glu Ser Arg Glu Leu Asp Asn Glu Asp Arg Val Asp Ser 
145                 150                 155                 160 


Lys Pro Glu Gly Gly Asp Ser Thr Gln Glu Ser Glu Ser Glu Glu His 
                165                 170                 175     


Trp Val Gly Gly Gly Ser Asp Gly Glu Ser Ser His Gly Asp Gly Ser 
            180                 185                 190         


Glu Leu Asp Asp Glu Gly Met Gln Ser Asp Asp Pro Glu Ser Ile Arg 
        195                 200                 205             


Ser Glu Arg Gly Asn Ser Arg Met Asn Ser Ala Gly Met Lys Ser Lys 
    210                 215                 220                 


Glu Ser Gly Glu Asn Ser Glu Gln Ala Asn Thr Gln Asp Ser Gly Gly 
225                 230                 235                 240 


Ser Gln Leu Leu Glu His Pro Ser Arg Lys Ile Phe Arg Lys Ser Arg 
                245                 250                 255     


Ile Ser Glu Glu Asp Asp Arg Ser Glu Leu Asp Asp Asn Asn Thr Met 
            260                 265                 270         


Glu Glu Val Lys Ser Asp Ser Thr Glu Asn Ser Asn Ser Arg Asp Thr 
        275                 280                 285             


Gly Leu Ser Gln Pro Arg Arg Asp Ser Lys Gly Asp Ser Gln Glu Asp 
    290                 295                 300                 


Ser Lys Glu Asn Leu Ser Gln Glu Glu Ser Gln Asn Val Asp Gly Pro 
305                 310                 315                 320 


Ser Ser Glu Ser Ser Gln Glu Ala Asn Leu Ser Ser Gln Glu Asn Ser 
                325                 330                 335     


Ser Glu Ser Gln Glu Glu Val Val Ser Glu Ser Arg Gly Asp Asn Pro 
            340                 345                 350         


Asp Pro Thr Thr Ser Tyr Val Glu Asp Gln Glu Asp Ser Asp Ser Ser 
        355                 360                 365             


Glu Glu Asp Ser Ser His Thr Leu Ser His Ser Lys Ser Glu Ser Arg 
    370                 375                 380                 


Glu Glu Gln Ala Asp Ser Glu Ser Ser Glu Ser Leu Asn Phe Ser Glu 
385                 390                 395                 400 


Glu Ser Pro Glu Ser Pro Glu Asp Glu Asn Ser Ser Ser Gln Glu Gly 
                405                 410                 415     


Leu Gln Ser His Ser Ser Ser Ala Glu Ser Gln Ser Glu Glu Ser His 
            420                 425                 430         


Ser Glu Glu Asp Asp Ser Asp Ser Gln Asp Ser Ser Arg Ser Lys Glu 
        435                 440                 445             


Asp Ser Asn Ser Thr Glu Ser Lys Ser Ser Ser Glu Glu Asp Gly Gln 
    450                 455                 460                 


Leu Lys Asn Ile Glu Ile Glu Ser Arg Lys Leu Thr Val Asp Ala Tyr 
465                 470                 475                 480 


His Asn Lys Pro Ile Gly Asp Gln Asp Asp Asn Asp Cys Gln Asp Gly 
                485                 490                 495     


Tyr 
    


<210>  2388
<211>  152
<212>  PRT
<213>  Homo Sapiens

<400>  2388

Ile Pro Leu Gly Val Asn Ser Gln Arg Gly Asp Asp Val Thr Gln Ala 
1               5                   10                  15      


Thr Pro Glu Thr Phe Thr Glu Asp Pro Asn Leu Val Asn Asp Pro Ala 
            20                  25                  30          


Thr Asp Glu Thr Val Leu Ala Val Leu Ala Asp Ile Ala Pro Ser Thr 
        35                  40                  45              


Asp Asp Leu Ala Ser Leu Ser Glu Lys Asn Thr Thr Ala Glu Cys Trp 
    50                  55                  60                  


Asp Glu Lys Phe Thr Cys Thr Arg Leu Tyr Ser Val His Arg Pro Val 
65                  70                  75                  80  


Lys Gln Cys Ile His Gln Leu Cys Phe Thr Ser Leu Arg Arg Met Tyr 
                85                  90                  95      


Ile Val Asn Lys Glu Ile Cys Ser Arg Leu Val Cys Lys Glu His Glu 
            100                 105                 110         


Ala Met Lys Asp Glu Leu Cys Arg Gln Met Ala Gly Leu Pro Pro Arg 
        115                 120                 125             


Arg Leu Arg Arg Ser Asn Tyr Phe Arg Leu Pro Pro Cys Glu Asn Val 
    130                 135                 140                 


Asp Leu Gln Arg Pro Asn Gly Leu 
145                 150         


<210>  2389
<211>  303
<212>  PRT
<213>  Homo Sapiens

<400>  2389

Glu Val Glu Lys Thr Ala Cys Pro Ser Gly Lys Lys Ala Pro Glu Ile 
1               5                   10                  15      


Asp Glu Ser Leu Ile Phe Tyr Lys Lys Trp Glu Leu Glu Ala Cys Val 
            20                  25                  30          


Asp Ala Ala Leu Leu Ala Thr Gln Met Asp Arg Val Asn Ala Ile Pro 
        35                  40                  45              


Phe Thr Tyr Glu Gln Leu Asp Val Leu Lys His Lys Leu Asp Glu Leu 
    50                  55                  60                  


Tyr Pro Gln Gly Tyr Pro Glu Ser Val Ile Gln His Leu Gly Tyr Leu 
65                  70                  75                  80  


Phe Leu Lys Met Ser Pro Glu Asp Ile Arg Lys Trp Asn Val Thr Ser 
                85                  90                  95      


Leu Glu Thr Leu Lys Ala Leu Leu Glu Val Asn Lys Gly His Glu Met 
            100                 105                 110         


Ser Pro Gln Val Ala Thr Leu Ile Asp Arg Phe Val Lys Gly Arg Gly 
        115                 120                 125             


Gln Leu Asp Lys Asp Thr Leu Asp Thr Leu Thr Ala Phe Tyr Pro Gly 
    130                 135                 140                 


Tyr Leu Cys Ser Leu Ser Pro Glu Glu Leu Ser Ser Val Pro Pro Ser 
145                 150                 155                 160 


Ser Ile Trp Ala Val Arg Pro Gln Asp Leu Asp Thr Cys Asp Pro Arg 
                165                 170                 175     


Gln Leu Asp Val Leu Tyr Pro Lys Ala Arg Leu Ala Phe Gln Asn Met 
            180                 185                 190         


Asn Gly Ser Glu Tyr Phe Val Lys Ile Gln Ser Phe Leu Gly Gly Ala 
        195                 200                 205             


Pro Thr Glu Asp Leu Lys Ala Leu Ser Gln Gln Asn Val Ser Met Asp 
    210                 215                 220                 


Leu Ala Thr Phe Met Lys Leu Arg Thr Asp Ala Val Leu Pro Leu Thr 
225                 230                 235                 240 


Val Ala Glu Val Gln Lys Leu Leu Gly Pro His Val Glu Gly Leu Lys 
                245                 250                 255     


Ala Glu Glu Arg His Arg Pro Val Arg Asp Trp Ile Leu Arg Gln Arg 
            260                 265                 270         


Gln Asp Asp Leu Asp Thr Leu Gly Leu Gly Leu Gln Gly Gly Ile Pro 
        275                 280                 285             


Asn Gly Tyr Leu Val Leu Asp Leu Ser Met Gln Glu Ala Leu Ser 
    290                 295                 300             


<210>  2390
<211>  587
<212>  PRT
<213>  Homo Sapiens

<400>  2390

Gly Gly Val Gly Ser Leu Asn Leu Glu Glu Leu Ser Glu Met Arg Tyr 
1               5                   10                  15      


Gly Ile Glu Ile Leu Pro Leu Pro Val Met Gly Gly Gln Ser Gln Ser 
            20                  25                  30          


Ser Asp Val Val Ile Val Ser Ser Lys Tyr Lys Gln Arg Tyr Glu Cys 
        35                  40                  45              


Arg Leu Pro Ala Gly Ala Ile His Phe Gln Arg Glu Arg Glu Glu Glu 
    50                  55                  60                  


Thr Pro Ala Tyr Gln Gly Pro Gly Ile Pro Glu Leu Leu Ser Pro Met 
65                  70                  75                  80  


Arg Asp Ala Pro Cys Leu Leu Lys Thr Lys Asp Trp Trp Thr Tyr Glu 
                85                  90                  95      


Phe Cys Tyr Gly Arg His Ile Gln Gln Tyr His Met Glu Asp Ser Glu 
            100                 105                 110         


Ile Lys Gly Glu Val Leu Tyr Leu Gly Tyr Tyr Gln Ser Ala Phe Asp 
        115                 120                 125             


Trp Asp Asp Glu Thr Ala Lys Ala Ser Lys Gln His Arg Leu Lys Arg 
    130                 135                 140                 


Tyr His Ser Gln Thr Tyr Gly Asn Gly Ser Lys Cys Asp Leu Asn Gly 
145                 150                 155                 160 


Arg Pro Arg Glu Ala Glu Val Arg Phe Leu Cys Asp Glu Gly Ala Gly 
                165                 170                 175     


Ile Ser Gly Asp Tyr Ile Asp Arg Val Asp Glu Pro Leu Ser Cys Ser 
            180                 185                 190         


Tyr Val Leu Thr Ile Arg Thr Pro Arg Leu Cys Pro His Pro Leu Leu 
        195                 200                 205             


Arg Pro Pro Pro Ser Ala Ala Pro Gln Ala Ile Leu Cys His Pro Ser 
    210                 215                 220                 


Leu Gln Pro Glu Glu Tyr Met Ala Tyr Val Gln Arg Gln Ala Asp Ser 
225                 230                 235                 240 


Lys Gln Tyr Gly Asp Lys Ile Ile Glu Glu Leu Gln Asp Leu Gly Pro 
                245                 250                 255     


Gln Val Trp Ser Glu Thr Lys Ser Gly Val Ala Pro Gln Lys Met Ala 
            260                 265                 270         


Gly Ala Ser Pro Thr Lys Asp Asp Ser Lys Asp Ser Asp Phe Trp Lys 
        275                 280                 285             


Met Leu Asn Glu Pro Glu Asp Gln Ala Pro Gly Gly Glu Glu Val Pro 
    290                 295                 300                 


Ala Glu Glu Gln Asp Pro Ser Pro Glu Ala Ala Asp Ser Ala Ser Gly 
305                 310                 315                 320 


Ala Pro Asn Asp Phe Gln Asn Asn Val Gln Val Lys Val Ile Arg Ser 
                325                 330                 335     


Pro Ala Asp Leu Ile Arg Phe Ile Glu Glu Leu Lys Gly Gly Thr Lys 
            340                 345                 350         


Lys Gly Lys Pro Asn Ile Gly Gln Glu Gln Pro Val Asp Asp Ala Ala 
        355                 360                 365             


Glu Val Pro Gln Arg Glu Pro Glu Lys Glu Arg Gly Asp Pro Glu Arg 
    370                 375                 380                 


Gln Arg Glu Met Glu Glu Glu Glu Asp Glu Asp Glu Asp Glu Asp Glu 
385                 390                 395                 400 


Asp Glu Asp Glu Arg Gln Leu Leu Gly Glu Phe Glu Lys Glu Leu Glu 
                405                 410                 415     


Gly Ile Leu Leu Pro Ser Asp Arg Asp Arg Leu Arg Ser Glu Val Lys 
            420                 425                 430         


Ala Gly Met Glu Arg Glu Leu Glu Asn Ile Ile Gln Glu Thr Glu Lys 
        435                 440                 445             


Glu Leu Asp Pro Asp Gly Leu Lys Lys Glu Ser Glu Arg Asp Arg Ala 
    450                 455                 460                 


Met Leu Ala Leu Thr Ser Thr Leu Asn Lys Leu Ile Lys Arg Leu Glu 
465                 470                 475                 480 


Glu Lys Gln Ser Pro Glu Leu Val Lys Lys His Lys Lys Lys Arg Val 
                485                 490                 495     


Val Pro Lys Lys Pro Pro Pro Ser Pro Gln Pro Thr Gly Lys Ile Glu 
            500                 505                 510         


Ile Lys Ile Val Arg Pro Trp Ala Glu Gly Thr Glu Glu Gly Ala Arg 
        515                 520                 525             


Trp Leu Thr Asp Glu Asp Thr Arg Asn Leu Lys Glu Ile Phe Phe Asn 
    530                 535                 540                 


Ile Leu Val Pro Gly Ala Glu Glu Ala Gln Lys Glu Arg Gln Arg Gln 
545                 550                 555                 560 


Lys Glu Leu Glu Ser Asn Tyr Arg Arg Val Trp Gly Ser Pro Gly Gly 
                565                 570                 575     


Glu Gly Thr Gly Asp Leu Asp Glu Phe Asp Phe 
            580                 585         


<210>  2391
<211>  171
<212>  PRT
<213>  Homo Sapiens

<400>  2391

Ala Gly Pro Pro Pro Ile Gln Asp Gly Glu Phe Thr Phe Leu Leu Pro 
1               5                   10                  15      


Ala Gly Arg Lys Gln Cys Phe Tyr Gln Ser Ala Pro Ala Asn Ala Ser 
            20                  25                  30          


Leu Glu Thr Glu Tyr Gln Val Ile Gly Gly Ala Gly Leu Asp Val Asp 
        35                  40                  45              


Phe Thr Leu Glu Ser Pro Gln Gly Val Leu Leu Val Ser Glu Ser Arg 
    50                  55                  60                  


Lys Ala Asp Gly Val His Thr Val Glu Pro Thr Glu Ala Gly Asp Tyr 
65                  70                  75                  80  


Lys Leu Cys Phe Asp Asn Ser Phe Ser Thr Ile Ser Glu Lys Leu Val 
                85                  90                  95      


Phe Phe Glu Leu Ile Phe Asp Ser Leu Gln Asp Asp Glu Glu Val Glu 
            100                 105                 110         


Gly Trp Ala Glu Ala Val Glu Pro Glu Glu Met Leu Asp Val Lys Met 
        115                 120                 125             


Glu Asp Ile Lys Glu Ser Ile Glu Thr Met Arg Thr Arg Leu Glu Arg 
    130                 135                 140                 


Ser Ile Gln Met Leu Thr Leu Leu Arg Ala Phe Glu Ala Arg Asp Arg 
145                 150                 155                 160 


Asn Leu Gln Glu Gly Asn Leu Glu Arg Val Asn 
                165                 170     


<210>  2392
<211>  212
<212>  PRT
<213>  Homo Sapiens

<400>  2392

Ala Ser Lys Ala Pro Val Cys Gln Glu Ile Thr Val Pro Met Cys Arg 
1               5                   10                  15      


Gly Ile Gly Tyr Asn Leu Thr His Met Pro Asn Gln Phe Asn His Asp 
            20                  25                  30          


Thr Gln Asp Glu Ala Gly Leu Glu Val His Gln Phe Trp Pro Leu Val 
        35                  40                  45              


Glu Ile Gln Cys Ser Pro Asp Leu Arg Phe Phe Leu Cys Ser Met Tyr 
    50                  55                  60                  


Thr Pro Ile Cys Leu Pro Asp Tyr His Lys Pro Leu Pro Pro Cys Arg 
65                  70                  75                  80  


Ser Val Cys Glu Arg Ala Lys Ala Gly Cys Ser Pro Leu Met Arg Gln 
                85                  90                  95      


Tyr Gly Phe Ala Trp Pro Glu Arg Met Ser Cys Asp Arg Leu Pro Val 
            100                 105                 110         


Leu Gly Arg Asp Ala Glu Val Leu Cys Met Asp Tyr Asn Arg Ser Glu 
        115                 120                 125             


Ala Thr Thr Ala Pro Pro Arg Pro Phe Pro Ala Lys Pro Thr Leu Pro 
    130                 135                 140                 


Gly Pro Pro Gly Ala Pro Ala Ser Gly Gly Glu Cys Pro Ala Gly Gly 
145                 150                 155                 160 


Pro Phe Val Cys Lys Cys Arg Glu Pro Phe Val Pro Ile Leu Lys Glu 
                165                 170                 175     


Ser His Pro Leu Tyr Asn Lys Val Arg Thr Gly Gln Val Pro Asn Cys 
            180                 185                 190         


Ala Val Pro Cys Tyr Gln Pro Ser Phe Ser Ala Asp Glu Arg Thr Phe 
        195                 200                 205             


Ala Thr Phe Trp 
    210         


<210>  2393
<211>  51
<212>  PRT
<213>  Homo Sapiens

<400>  2393

Thr Ala Arg Phe Leu Ala Phe Leu Gln Ala Thr Lys Ala Gln Gln Tyr 
1               5                   10                  15      


Val Asp Ser Tyr Val Gln Glu Ser Asp Leu Ser Glu Val Thr Leu Pro 
            20                  25                  30          


Pro Glu Ile Gln Tyr Phe Thr Tyr Ala Arg Asp Lys Trp Leu Pro Ser 
        35                  40                  45              


Asp Pro Gln 
    50      


<210>  2394
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  2394

Glu Val Leu Asp Met Ala Asp Asn Ala Phe Asp Asp Glu Tyr Leu Lys 
1               5                   10                  15      


Cys Thr Asp Arg Met Glu Ile Lys Tyr Val Pro Gln Leu Leu Lys Glu 
            20                  25                  30          


Glu Lys Ala Ser His Gln Gln Leu Asp Thr Val Trp Glu Asn Ala Lys 
        35                  40                  45              


Ala Lys Trp Ala Ala Arg Lys Thr Gln Ile Phe Leu Pro Met Asn Phe 
    50                  55                  60                  


Lys Asp Asn His Gly Ile Ala Leu Met Ala Tyr Ile Ser Glu Ala Gln 
65                  70                  75                  80  


Glu Gln Thr Pro Phe Tyr His Leu Phe Ser Glu Ala Val Lys Met Ala 
                85                  90                  95      


Gly Gln Ser Arg Glu Asp Tyr Ile Tyr Gly Phe Gln Phe Lys Ala Phe 
            100                 105                 110         


His Phe Tyr Leu Thr Arg Ala Leu Gln Leu Leu Arg Lys Pro Cys Glu 
        115                 120                 125             


Ala Ser Ser Lys Thr Val Val Tyr Arg Thr Ser Gln Gly Thr Ser Phe 
    130                 135                 140                 


Thr Phe Gly Gly Leu Asn Gln Ala Arg Phe Gly His Phe Thr Leu Ala 
145                 150                 155                 160 


Tyr Ser Ala Lys Pro Gln Ala Ala Asn Asp Gln Leu Thr Val Leu Ser 
                165                 170                 175     


Ile Tyr Thr Cys Leu Gly Val Asp Ile Glu Asn Phe Leu Asp Lys Glu 
            180                 185                 190         


Ser Glu Arg Ile Thr Leu Ile Pro Leu Asn Glu Val Phe Gln Val Ser 
        195                 200                 205             


Gln Glu Gly Ala Gly Asn Asn Leu Ile Leu Gln Ser Ile Asn Lys Thr 
    210                 215                 220                 


Cys Ser His Tyr Glu Cys Ala Phe Leu Gly Gly Leu Lys Thr Glu Asn 
225                 230                 235                 240 


Cys Ile Glu Asn Leu Glu Tyr Phe Gln Pro Ile Tyr Val Tyr Asn Pro 
                245                 250                 255     


Gly Glu Lys Asn Gln Lys Leu Glu Asp His Ser Glu Lys Asn Trp Lys 
            260                 265                 270         


Leu Glu Asp His Gly Glu Lys Asn Gln Lys Leu Glu Asp His Gly Val 
        275                 280                 285             


Lys Ile Leu Glu Pro Thr Gln Ile Pro Gly Met Lys Ile Pro Glu Pro 
    290                 295                 300                 


Phe Pro Leu Pro Glu Asp Lys Ser Gln Gly Asn Ile Asn Asn Pro Thr 
305                 310                 315                 320 


Pro Gly Pro Val Pro Val Pro Gly Pro Lys Ser His Pro Ser Ala Ser 
                325                 330                 335     


<210>  2395
<211>  96
<212>  PRT
<213>  Homo Sapiens

<400>  2395

Met Gly Ala Val Leu Gly Val Phe Ser Leu Ala Ser Trp Val Pro Cys 
1               5                   10                  15      


Leu Cys Ser Gly Ala Ser Cys Leu Leu Cys Ser Cys Cys Pro Asn Ser 
            20                  25                  30          


Lys Asn Ser Thr Val Thr Arg Leu Ile Tyr Ala Phe Ile Leu Leu Leu 
        35                  40                  45              


Ser Thr Val Val Ser Tyr Ile Met Gln Arg Lys Glu Met Glu Thr Tyr 
    50                  55                  60                  


Leu Lys Lys Ile Pro Gly Phe Cys Glu Gly Gly Phe Lys Ile His Glu 
65                  70                  75                  80  


Ala Asp Ile Asn Ala Asp Lys Asp Cys Asp Val Leu Val Gly Tyr Lys 
                85                  90                  95      


<210>  2396
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  2396

Met Ser Ser Asn Val Tyr Tyr Tyr Thr Arg Met Met Ser Gln Leu Phe 
1               5                   10                  15      


Leu Asp Thr Pro Val Ser Lys Thr Glu Lys Thr Asn Phe Lys Thr Leu 
            20                  25                  30          


Ser Ser Met Glu Asp Phe Trp Lys Phe Thr Glu Gly Ser Leu Leu Asp 
        35                  40                  45              


Gly Leu Tyr Trp Lys Met Gln Pro Ser Asn Gln Thr Glu Ala Asp Asn 
    50                  55                  60                  


Arg Ser Phe Ile Phe Tyr Glu Asn Leu Leu Leu Gly Val Pro Arg Ile 
65                  70                  75                  80  


Arg Gln Leu Arg Val Arg Asn Gly Ser Cys Ser Ile Pro Gln Asp Leu 
                85                  90                  95      


Arg Asp Glu Ile Lys Glu Cys Tyr Asp Val Tyr Ser Val Ser Ser Glu 
            100                 105                 110         


Asp Arg Ala Pro Phe Gly Pro Arg Asn Gly Thr Ala Trp Ile Tyr Thr 
        115                 120                 125             


Ser Glu Lys Asp Leu Asn Gly Ser Ser His Trp Gly Ile Ile Ala Thr 
    130                 135                 140                 


Tyr Ser Gly Ala Gly Tyr Tyr Leu Asp Leu Ser Arg Thr Arg Glu Glu 
145                 150                 155                 160 


Thr Ala Ala Gln Val Ala Ser Leu Lys Lys Asn Val Trp Leu Asp Arg 
                165                 170                 175     


Gly Thr Arg Ala Thr Phe Ile Asp Phe Ser Val Tyr Asn Ala Asn Ile 
            180                 185                 190         


Asn Leu Phe Cys Val Val Arg Leu Leu Val Glu Phe Pro Ala Thr Gly 
        195                 200                 205             


Gly Val Ile Pro Ser Trp Gln Phe Gln Pro Leu Lys Leu Ile Arg Tyr 
    210                 215                 220                 


Val Thr Thr 
225         


<210>  2397
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  2397

Met Arg Ile Cys Ser Phe Asn Val Arg Ser Phe Gly Glu Ser Lys Gln 
1               5                   10                  15      


Glu Asp Lys Asn Ala Met Asp Val Ile Val Lys Val Ile Lys Arg Cys 
            20                  25                  30          


Asp Ile Ile Leu Val Met Glu Ile Lys Asp Ser Asn Asn Arg Ile Cys 
        35                  40                  45              


Pro Ile Leu Met Glu Lys Leu Asn Arg Asn Ser Arg Arg Gly Ile Thr 
    50                  55                  60                  


Tyr Asn Tyr Val Ile Ser Ser Arg Leu Gly Arg Asn Thr Tyr Lys Glu 
65                  70                  75                  80  


Gln Tyr Ala Phe Leu Tyr Lys Glu Lys Leu Val Ser Val Lys Arg Ser 
                85                  90                  95      


Tyr His Tyr His Asp Tyr Gln Asp Gly Asp Ala Asp Val Phe Ser Arg 
            100                 105                 110         


Glu Pro Phe Val Val Trp Phe Gln Ser Pro His Thr Ala Val Lys Asp 
        115                 120                 125             


Phe Val Ile Ile Pro Leu His Thr Thr Pro Glu Thr Ser Val Lys Glu 
    130                 135                 140                 


Ile Asp Glu Leu Val Glu Val Tyr Thr Asp Val Lys His Arg Trp Lys 
145                 150                 155                 160 


Ala Glu Asn Phe Ile Phe Met Gly Asp Phe Asn Ala Gly Cys Ser Tyr 
                165                 170                 175     


Val Pro Lys Lys Ala Trp Lys Asn Ile Arg Leu Arg Thr Asp Pro Arg 
            180                 185                 190         


Phe Val Trp Leu Ile Gly Asp Gln Glu Asp Thr Thr Val Lys Lys Ser 
        195                 200                 205             


Thr Asn Cys Ala Tyr Asp Arg Ile Val Leu Arg Gly Gln Glu Ile Val 
    210                 215                 220                 


Ser Ser Val Val Pro Lys Ser Asn Ser Val Phe Asp Phe Gln Lys Ala 
225                 230                 235                 240 


Tyr Lys Leu Thr Glu Glu Glu Ala Leu Asp Val Ser Asp His Phe Pro 
                245                 250                 255     


Val Glu Phe Lys Leu Gln Ser Ser Arg Ala Phe Thr Asn Ser Lys Lys 
            260                 265                 270         


Ser Val Thr Leu Arg Lys Lys Thr Lys Ser Lys Arg Ser 
        275                 280                 285 


<210>  2398
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  2398

Ser Gly Arg Gly Glu Ala Glu Thr Arg Glu Cys Ile Tyr Tyr Asn Ala 
1               5                   10                  15      


Asn Trp Glu Leu Glu Arg Thr Asn Gln Ser Gly Leu Glu Arg Cys Glu 
            20                  25                  30          


Gly Glu Gln Asp Lys Arg Leu His Cys Tyr Ala Ser Trp Arg Asn Ser 
        35                  40                  45              


Ser Gly Thr Ile Glu Leu Val Lys Lys Gly Cys Trp Leu Asp Asp Phe 
    50                  55                  60                  


Asn Cys Tyr Asp Arg Gln Glu Cys Val Ala Thr Glu Glu Asn Pro Gln 
65                  70                  75                  80  


Val Tyr Phe Cys Cys Cys Glu Gly Asn Phe Cys Asn Glu Arg Phe Thr 
                85                  90                  95      


His Leu Pro Glu Ala Gly Gly Pro Glu Val Thr Tyr Glu Pro Pro Pro 
            100                 105                 110         


Thr Ala Pro Thr Leu Leu Thr 
        115                 


<210>  2399
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2399

Ser Leu Pro Thr Glu Asp Cys Glu Asn Glu Lys Glu Gln Ala Val His 
1               5                   10                  15      


Asn Val Val Gln Leu Leu Pro Gly Val Gly Thr Phe Tyr Asn Leu Gly 
            20                  25                  30          


Thr Ala Leu Tyr Tyr Ala Thr Gln Asn Cys Leu Gly Lys Ala Arg Glu 
        35                  40                  45              


Arg Gly Arg Asp Gly Ala Ile Asp Leu Gly Tyr Asp Leu Leu Met Thr 
    50                  55                  60                  


Met Ala Gly Met Ser Gly Gly Pro Met Gly Leu Ala Ile Ser Ala Ala 
65                  70                  75                  80  


Leu Lys Pro Ala Leu Arg Ser Gly Val Gln Gln Leu Ile Gln Tyr Tyr 
                85                  90                  95      


Gln Asp Gln Lys Asp Ala Asn Ile Ser Gln Pro Glu Thr Thr Lys Glu 
            100                 105                 110         


Gly Leu Arg Ala Ile Ser Asp Val Ser Asp Leu Glu Glu Thr Thr Thr 
        115                 120                 125             


Leu Ala Ser Phe Ile Ser Glu Val Val Ser Ser Ala Pro Tyr Trp Gly 
    130                 135                 140                 


Trp Ala Ile Ile Lys Ser Tyr Asp Leu Asp Pro Gly Ala Gly Ser Leu 
145                 150                 155                 160 


Glu Ile 
        


<210>  2400
<211>  828
<212>  PRT
<213>  Homo Sapiens

<400>  2400

Ala Glu Gly Trp Glu Glu Gly Pro Pro Thr Val Leu Ser Asp Ser Pro 
1               5                   10                  15      


Trp Thr Asn Ile Ser Gly Ser Cys Lys Gly Arg Cys Phe Glu Leu Gln 
            20                  25                  30          


Glu Ala Gly Pro Pro Asp Cys Arg Cys Asp Asn Leu Cys Lys Ser Tyr 
        35                  40                  45              


Thr Ser Cys Cys His Asp Phe Asp Glu Leu Cys Leu Lys Thr Ala Arg 
    50                  55                  60                  


Gly Trp Glu Cys Thr Lys Asp Arg Cys Gly Glu Val Arg Asn Glu Glu 
65                  70                  75                  80  


Asn Ala Cys His Cys Ser Glu Asp Cys Leu Ala Arg Gly Asp Cys Cys 
                85                  90                  95      


Thr Asn Tyr Gln Val Val Cys Lys Gly Glu Ser His Trp Val Asp Asp 
            100                 105                 110         


Asp Cys Glu Glu Ile Lys Ala Ala Glu Cys Pro Ala Gly Phe Val Arg 
        115                 120                 125             


Pro Pro Leu Ile Ile Phe Ser Val Asp Gly Phe Arg Ala Ser Tyr Met 
    130                 135                 140                 


Lys Lys Gly Ser Lys Val Met Pro Asn Ile Glu Lys Leu Arg Ser Cys 
145                 150                 155                 160 


Gly Thr His Ser Pro Tyr Met Arg Pro Val Tyr Pro Thr Lys Thr Phe 
                165                 170                 175     


Pro Asn Leu Tyr Thr Leu Ala Thr Gly Leu Tyr Pro Glu Ser His Gly 
            180                 185                 190         


Ile Val Gly Asn Ser Met Tyr Asp Pro Val Phe Asp Ala Thr Phe His 
        195                 200                 205             


Leu Arg Gly Arg Glu Lys Phe Asn His Arg Trp Trp Gly Gly Gln Pro 
    210                 215                 220                 


Leu Trp Ile Thr Ala Thr Lys Gln Gly Val Lys Ala Gly Thr Phe Phe 
225                 230                 235                 240 


Trp Ser Val Val Ile Pro His Glu Arg Arg Ile Leu Thr Ile Leu Gln 
                245                 250                 255     


Trp Leu Thr Leu Pro Asp His Glu Arg Pro Ser Val Tyr Ala Phe Tyr 
            260                 265                 270         


Ser Glu Gln Pro Asp Phe Ser Gly His Lys Tyr Gly Pro Phe Gly Pro 
        275                 280                 285             


Glu Met Thr Asn Pro Leu Arg Glu Ile Asp Lys Ile Val Gly Gln Leu 
    290                 295                 300                 


Met Asp Gly Leu Lys Gln Leu Lys Leu His Arg Cys Val Asn Val Ile 
305                 310                 315                 320 


Phe Val Gly Asp His Gly Met Glu Asp Val Thr Cys Asp Arg Thr Glu 
                325                 330                 335     


Phe Leu Ser Asn Tyr Leu Thr Asn Val Asp Asp Ile Thr Leu Val Pro 
            340                 345                 350         


Gly Thr Leu Gly Arg Ile Arg Ser Lys Phe Ser Asn Asn Ala Lys Tyr 
        355                 360                 365             


Asp Pro Lys Ala Ile Ile Ala Asn Leu Thr Cys Lys Lys Pro Asp Gln 
    370                 375                 380                 


His Phe Lys Pro Tyr Leu Lys Gln His Leu Pro Lys Arg Leu His Tyr 
385                 390                 395                 400 


Ala Asn Asn Arg Arg Ile Glu Asp Ile His Leu Leu Val Glu Arg Arg 
                405                 410                 415     


Trp His Val Ala Arg Lys Pro Leu Asp Val Tyr Lys Lys Pro Ser Gly 
            420                 425                 430         


Lys Cys Phe Phe Gln Gly Asp His Gly Phe Asp Asn Lys Val Asn Ser 
        435                 440                 445             


Met Gln Thr Val Phe Val Gly Tyr Gly Pro Thr Phe Lys Tyr Lys Thr 
    450                 455                 460                 


Lys Val Pro Pro Phe Glu Asn Ile Glu Leu Tyr Asn Val Met Cys Asp 
465                 470                 475                 480 


Leu Leu Gly Leu Lys Pro Ala Pro Asn Asn Gly Thr His Gly Ser Leu 
                485                 490                 495     


Asn His Leu Leu Arg Thr Asn Thr Phe Arg Pro Thr Met Pro Glu Glu 
            500                 505                 510         


Val Thr Arg Pro Asn Tyr Pro Gly Ile Met Tyr Leu Gln Ser Asp Phe 
        515                 520                 525             


Asp Leu Gly Cys Thr Cys Asp Asp Lys Val Glu Pro Lys Asn Lys Leu 
    530                 535                 540                 


Asp Glu Leu Asn Lys Arg Leu His Thr Lys Gly Ser Thr Glu Glu Arg 
545                 550                 555                 560 


His Leu Leu Tyr Gly Arg Pro Ala Val Leu Tyr Arg Thr Arg Tyr Asp 
                565                 570                 575     


Ile Leu Tyr His Thr Asp Phe Glu Ser Gly Tyr Ser Glu Ile Phe Leu 
            580                 585                 590         


Met Pro Leu Trp Thr Ser Tyr Thr Val Ser Lys Gln Ala Glu Val Ser 
        595                 600                 605             


Ser Val Pro Asp His Leu Thr Ser Cys Val Arg Pro Asp Val Arg Val 
    610                 615                 620                 


Ser Pro Ser Phe Ser Gln Asn Cys Leu Ala Tyr Lys Asn Asp Lys Gln 
625                 630                 635                 640 


Met Ser Tyr Gly Phe Leu Phe Pro Pro Tyr Leu Ser Ser Ser Pro Glu 
                645                 650                 655     


Ala Lys Tyr Asp Ala Phe Leu Val Thr Asn Met Val Pro Met Tyr Pro 
            660                 665                 670         


Ala Phe Lys Arg Val Trp Asn Tyr Phe Gln Arg Val Leu Val Lys Lys 
        675                 680                 685             


Tyr Ala Ser Glu Arg Asn Gly Val Asn Val Ile Ser Gly Pro Ile Phe 
    690                 695                 700                 


Asp Tyr Asp Tyr Asp Gly Leu His Asp Thr Glu Asp Lys Ile Lys Gln 
705                 710                 715                 720 


Tyr Val Glu Gly Ser Ser Ile Pro Val Pro Thr His Tyr Tyr Ser Ile 
                725                 730                 735     


Ile Thr Ser Cys Leu Asp Phe Thr Gln Pro Ala Asp Lys Cys Asp Gly 
            740                 745                 750         


Pro Leu Ser Val Ser Ser Phe Ile Leu Pro His Arg Pro Asp Asn Glu 
        755                 760                 765             


Glu Ser Cys Asn Ser Ser Glu Asp Glu Ser Lys Trp Val Glu Glu Leu 
    770                 775                 780                 


Met Lys Met His Thr Ala Arg Val Arg Asp Ile Glu His Leu Thr Ser 
785                 790                 795                 800 


Leu Asp Phe Phe Arg Lys Thr Ser Arg Ser Tyr Pro Glu Ile Leu Thr 
                805                 810                 815     


Leu Lys Thr Tyr Leu His Thr Tyr Glu Ser Glu Ile 
            820                 825             


<210>  2401
<211>  659
<212>  PRT
<213>  Homo Sapiens

<400>  2401

Gln Arg Val Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly 
1               5                   10                  15      


Lys Pro Gly Gln Asp Gly Ile Asp Gly Glu Ala Gly Pro Pro Gly Leu 
            20                  25                  30          


Pro Gly Pro Pro Gly Pro Lys Gly Ala Pro Gly Lys Pro Gly Lys Pro 
        35                  40                  45              


Gly Glu Ala Gly Leu Pro Gly Leu Pro Gly Val Asp Gly Leu Thr Gly 
    50                  55                  60                  


Arg Asp Gly Pro Pro Gly Pro Lys Gly Ala Pro Gly Glu Arg Gly Ser 
65                  70                  75                  80  


Leu Gly Pro Pro Gly Pro Pro Gly Leu Gly Gly Lys Gly Leu Pro Gly 
                85                  90                  95      


Pro Pro Gly Glu Ala Gly Val Ser Gly Pro Pro Gly Gly Ile Gly Leu 
            100                 105                 110         


Arg Gly Pro Pro Gly Pro Ser Gly Leu Pro Gly Leu Pro Gly Pro Pro 
        115                 120                 125             


Gly Pro Pro Gly Pro Pro Gly His Pro Gly Val Leu Pro Glu Gly Ala 
    130                 135                 140                 


Thr Asp Leu Gln Cys Pro Ser Ile Cys Pro Pro Gly Pro Pro Gly Pro 
145                 150                 155                 160 


Pro Gly Met Pro Gly Phe Lys Gly Pro Thr Gly Tyr Lys Gly Glu Gln 
                165                 170                 175     


Gly Glu Val Gly Lys Asp Gly Glu Lys Gly Asp Pro Gly Pro Pro Gly 
            180                 185                 190         


Pro Ala Gly Leu Pro Gly Ser Val Gly Leu Gln Gly Pro Arg Gly Leu 
        195                 200                 205             


Arg Gly Leu Pro Gly Pro Leu Gly Pro Pro Gly Asp Arg Gly Pro Ile 
    210                 215                 220                 


Gly Phe Arg Gly Pro Pro Gly Ile Pro Gly Ala Pro Gly Lys Ala Gly 
225                 230                 235                 240 


Asp Arg Gly Glu Arg Gly Pro Glu Gly Phe Arg Gly Pro Lys Gly Asp 
                245                 250                 255     


Leu Gly Arg Pro Gly Pro Lys Gly Thr Pro Gly Val Ala Gly Pro Ser 
            260                 265                 270         


Gly Glu Pro Gly Met Pro Gly Lys Asp Gly Gln Asn Gly Val Pro Gly 
        275                 280                 285             


Leu Asp Gly Gln Lys Gly Glu Ala Gly Arg Asn Gly Ala Pro Gly Glu 
    290                 295                 300                 


Lys Gly Pro Asn Gly Leu Pro Gly Leu Pro Gly Arg Ala Gly Ser Lys 
305                 310                 315                 320 


Gly Glu Lys Gly Glu Arg Gly Arg Ala Gly Glu Leu Gly Glu Ala Gly 
                325                 330                 335     


Pro Ser Gly Glu Pro Gly Val Pro Gly Asp Ala Gly Met Pro Gly Glu 
            340                 345                 350         


Arg Gly Glu Ala Gly His Arg Gly Ser Ala Gly Ala Leu Gly Pro Gln 
        355                 360                 365             


Gly Pro Pro Gly Ala Pro Gly Val Arg Gly Phe Gln Gly Gln Lys Gly 
    370                 375                 380                 


Ser Met Gly Asp Pro Gly Leu Pro Gly Pro Gln Gly Leu Arg Gly Asp 
385                 390                 395                 400 


Val Gly Asp Arg Gly Pro Gly Gly Ala Ala Gly Pro Lys Gly Asp Gln 
                405                 410                 415     


Gly Ile Ala Gly Ser Asp Gly Leu Pro Gly Asp Lys Gly Glu Leu Gly 
            420                 425                 430         


Pro Ser Gly Leu Val Gly Pro Lys Gly Glu Ser Gly Ser Arg Gly Glu 
        435                 440                 445             


Leu Gly Pro Lys Gly Thr Gln Gly Pro Asn Gly Thr Ser Gly Val Gln 
    450                 455                 460                 


Gly Val Pro Gly Pro Pro Gly Pro Leu Gly Leu Gln Gly Val Pro Gly 
465                 470                 475                 480 


Val Pro Gly Ile Thr Gly Lys Pro Gly Val Pro Gly Lys Glu Ala Ser 
                485                 490                 495     


Glu Gln Arg Ile Arg Glu Leu Cys Gly Gly Met Ile Ser Glu Gln Ile 
            500                 505                 510         


Ala Gln Leu Ala Ala His Leu Arg Lys Pro Leu Ala Pro Gly Ser Ile 
        515                 520                 525             


Gly Arg Pro Gly Pro Ala Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly 
    530                 535                 540                 


Ser Ile Gly His Pro Gly Ala Arg Gly Pro Pro Gly Tyr Arg Gly Pro 
545                 550                 555                 560 


Thr Gly Glu Leu Gly Asp Pro Gly Pro Arg Gly Asn Gln Gly Asp Arg 
                565                 570                 575     


Gly Asp Lys Gly Ala Ala Gly Ala Gly Leu Asp Gly Pro Glu Gly Asp 
            580                 585                 590         


Gln Gly Pro Gln Gly Pro Gln Gly Val Pro Gly Thr Ser Lys Asp Gly 
        595                 600                 605             


Gln Asp Gly Ala Pro Gly Glu Pro Gly Pro Pro Gly Asp Pro Gly Leu 
    610                 615                 620                 


Pro Gly Ala Ile Gly Ala Gln Gly Thr Pro Gly Ile Cys Asp Thr Ser 
625                 630                 635                 640 


Ala Cys Gln Gly Ala Val Leu Gly Gly Val Gly Glu Lys Ser Gly Ser 
                645                 650                 655     


Arg Ser Ser 
            


<210>  2402
<211>  293
<212>  PRT
<213>  Homo Sapiens

<400>  2402

Leu Gln Leu Trp Asp Thr Trp Ala Asp Glu Ala Glu Lys Ala Leu Gly 
1               5                   10                  15      


Pro Leu Leu Ala Arg Asp Arg Arg Gln Ala Thr Glu Tyr Glu Tyr Leu 
            20                  25                  30          


Asp Tyr Asp Phe Leu Pro Glu Thr Glu Pro Pro Glu Met Leu Arg Asn 
        35                  40                  45              


Ser Thr Asp Thr Thr Pro Leu Thr Gly Pro Gly Thr Pro Glu Ser Thr 
    50                  55                  60                  


Thr Val Glu Pro Ala Ala Arg Arg Ser Thr Gly Leu Asp Ala Gly Gly 
65                  70                  75                  80  


Ala Val Thr Glu Leu Thr Thr Glu Leu Ala Asn Met Gly Asn Leu Ser 
                85                  90                  95      


Thr Asp Ser Ala Ala Met Glu Ile Gln Thr Thr Gln Pro Ala Ala Thr 
            100                 105                 110         


Glu Ala Gln Thr Thr Pro Leu Ala Ala Thr Glu Ala Gln Thr Thr Arg 
        115                 120                 125             


Leu Thr Ala Thr Glu Ala Gln Thr Thr Pro Leu Ala Ala Thr Glu Ala 
    130                 135                 140                 


Gln Thr Thr Pro Pro Ala Ala Thr Glu Ala Gln Thr Thr Gln Pro Thr 
145                 150                 155                 160 


Gly Leu Glu Ala Gln Thr Thr Ala Pro Ala Ala Met Glu Ala Gln Thr 
                165                 170                 175     


Thr Ala Pro Ala Ala Met Glu Ala Gln Thr Thr Pro Pro Ala Ala Met 
            180                 185                 190         


Glu Ala Gln Thr Thr Gln Thr Thr Ala Met Glu Ala Gln Thr Thr Ala 
        195                 200                 205             


Pro Glu Ala Thr Glu Ala Gln Thr Thr Gln Pro Thr Ala Thr Glu Ala 
    210                 215                 220                 


Gln Thr Thr Pro Leu Ala Ala Met Glu Ala Leu Ser Thr Glu Pro Ser 
225                 230                 235                 240 


Ala Thr Glu Ala Leu Ser Met Glu Pro Thr Thr Lys Arg Gly Leu Phe 
                245                 250                 255     


Ile Pro Phe Ser Val Ser Ser Val Thr His Lys Gly Ile Pro Met Ala 
            260                 265                 270         


Ala Ser Asn Leu Ser Val Asn Tyr Pro Val Gly Ala Pro Asp His Ile 
        275                 280                 285             


Ser Val Lys Gln Cys 
    290             


<210>  2403
<211>  295
<212>  PRT
<213>  Homo Sapiens

<400>  2403

Gly Lys Ala Glu Glu Leu His Tyr Pro Leu Gly Glu Arg Arg Ser Asp 
1               5                   10                  15      


Tyr Asp Arg Glu Ala Leu Leu Gly Val Gln Glu Asp Val Asp Glu Tyr 
            20                  25                  30          


Val Lys Leu Gly His Glu Glu Gln Gln Lys Arg Leu Gln Ala Ile Ile 
        35                  40                  45              


Lys Lys Ile Asp Leu Asp Ser Asp Gly Phe Leu Thr Glu Ser Glu Leu 
    50                  55                  60                  


Ser Ser Trp Ile Gln Met Ser Phe Lys His Tyr Ala Met Gln Glu Ala 
65                  70                  75                  80  


Lys Gln Gln Phe Val Glu Tyr Asp Lys Asn Ser Asp Asp Thr Val Thr 
                85                  90                  95      


Trp Asp Glu Tyr Asn Ile Gln Met Tyr Asp Arg Val Ile Asp Phe Asp 
            100                 105                 110         


Glu Asn Thr Ala Leu Asp Asp Ala Glu Glu Glu Ser Phe Arg Lys Leu 
        115                 120                 125             


His Leu Lys Asp Lys Lys Arg Phe Glu Lys Ala Asn Gln Asp Ser Gly 
    130                 135                 140                 


Pro Gly Leu Ser Leu Glu Glu Phe Ile Ala Phe Glu His Pro Glu Glu 
145                 150                 155                 160 


Val Asp Tyr Met Thr Glu Phe Val Ile Gln Glu Ala Leu Glu Glu His 
                165                 170                 175     


Asp Lys Asn Gly Asp Gly Phe Val Ser Leu Glu Glu Phe Leu Gly Asp 
            180                 185                 190         


Tyr Arg Trp Asp Pro Thr Ala Asn Glu Asp Pro Glu Trp Ile Leu Val 
        195                 200                 205             


Glu Lys Asp Arg Phe Val Asn Asp Tyr Asp Lys Asp Asn Asp Gly Arg 
    210                 215                 220                 


Leu Asp Pro Gln Glu Leu Leu Pro Trp Val Val Pro Asn Asn Gln Gly 
225                 230                 235                 240 


Ile Ala Gln Glu Glu Ala Leu His Leu Ile Asp Glu Met Asp Leu Asn 
                245                 250                 255     


Gly Asp Lys Lys Leu Ser Glu Glu Glu Ile Leu Glu Asn Pro Asp Leu 
            260                 265                 270         


Phe Leu Thr Ser Glu Ala Thr Asp Tyr Gly Arg Gln Leu His Asp Asp 
        275                 280                 285             


Tyr Phe Tyr His Asp Glu Leu 
    290                 295 


<210>  2404
<211>  416
<212>  PRT
<213>  Homo Sapiens

<400>  2404

Asn Asn Glu Thr Glu Glu Ile Lys Asp Glu Arg Ala Lys Asp Val Cys 
1               5                   10                  15      


Pro Val Arg Leu Glu Ser Arg Gly Lys Cys Glu Glu Ala Gly Glu Cys 
            20                  25                  30          


Pro Tyr Gln Val Ser Leu Pro Pro Leu Thr Ile Gln Leu Pro Lys Gln 
        35                  40                  45              


Phe Ser Arg Ile Glu Glu Val Phe Lys Glu Val Gln Asn Leu Lys Glu 
    50                  55                  60                  


Ile Val Asn Ser Leu Lys Lys Ser Cys Gln Asp Cys Lys Leu Gln Ala 
65                  70                  75                  80  


Asp Asp Asn Gly Asp Pro Gly Arg Asn Gly Leu Leu Leu Pro Ser Thr 
                85                  90                  95      


Gly Ala Pro Gly Glu Val Gly Asp Asn Arg Val Arg Glu Leu Glu Ser 
            100                 105                 110         


Glu Val Asn Lys Leu Ser Ser Glu Leu Lys Asn Ala Lys Glu Glu Ile 
        115                 120                 125             


Asn Val Leu His Gly Arg Leu Glu Lys Leu Asn Leu Val Asn Met Asn 
    130                 135                 140                 


Asn Ile Glu Asn Tyr Val Asp Ser Lys Val Ala Asn Leu Thr Phe Val 
145                 150                 155                 160 


Val Asn Ser Leu Asp Gly Lys Cys Ser Lys Cys Pro Ser Gln Glu Gln 
                165                 170                 175     


Ile Gln Ser Arg Pro Val Gln His Leu Ile Tyr Lys Asp Cys Ser Asp 
            180                 185                 190         


Tyr Tyr Ala Ile Gly Lys Arg Ser Ser Glu Thr Tyr Arg Val Thr Pro 
        195                 200                 205             


Asp Pro Lys Asn Ser Ser Phe Glu Val Tyr Cys Asp Met Glu Thr Met 
    210                 215                 220                 


Gly Gly Gly Trp Thr Val Leu Gln Ala Arg Leu Asp Gly Ser Thr Asn 
225                 230                 235                 240 


Phe Thr Arg Thr Trp Gln Asp Tyr Lys Ala Gly Phe Gly Asn Leu Arg 
                245                 250                 255     


Arg Glu Phe Trp Leu Gly Asn Asp Lys Ile His Leu Leu Thr Lys Ser 
            260                 265                 270         


Lys Glu Met Ile Leu Arg Ile Asp Leu Glu Asp Phe Asn Gly Val Glu 
        275                 280                 285             


Leu Tyr Ala Leu Tyr Asp Gln Phe Tyr Val Ala Asn Glu Phe Leu Lys 
    290                 295                 300                 


Tyr Arg Leu His Val Gly Asn Tyr Asn Gly Thr Ala Gly Asp Ala Leu 
305                 310                 315                 320 


Arg Phe Asn Lys His Tyr Asn His Asp Leu Lys Phe Phe Thr Thr Pro 
                325                 330                 335     


Asp Lys Asp Asn Asp Arg Tyr Pro Ser Gly Asn Cys Gly Leu Tyr Tyr 
            340                 345                 350         


Ser Ser Gly Trp Trp Phe Asp Ala Cys Leu Ser Ala Asn Leu Asn Gly 
        355                 360                 365             


Lys Tyr Tyr His Gln Lys Tyr Arg Gly Val Arg Asn Gly Ile Phe Trp 
    370                 375                 380                 


Gly Thr Trp Pro Gly Val Ser Glu Ala His Pro Gly Gly Tyr Lys Ser 
385                 390                 395                 400 


Ser Phe Lys Glu Ala Lys Met Met Ile Arg Pro Lys His Phe Lys Pro 
                405                 410                 415     


<210>  2405
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  2405

Val Gln Thr Val Pro Leu Ser Arg Leu Phe Asp His Ala Met Leu Gln 
1               5                   10                  15      


Ala His Arg Ala His Gln Leu Ala Ile Asp Thr Tyr Gln Glu Phe Glu 
            20                  25                  30          


Glu Thr Tyr Ile Pro Lys Asp Gln Lys Tyr Ser Phe Leu His Asp Ser 
        35                  40                  45              


Gln Thr Ser Phe Cys Phe Ser Asp Ser Ile Pro Thr Pro Ser Asn Met 
    50                  55                  60                  


Glu Glu Thr Gln Gln Lys Ser Asn Leu Glu Leu Leu Arg Ile Ser Leu 
65                  70                  75                  80  


Leu Leu Ile Glu Ser Trp Leu Glu Pro Val Arg Phe Leu Arg Ser Met 
                85                  90                  95      


Phe Ala Asn Asn Leu Val Tyr Asp Thr Ser Asp Ser Asp Asp Tyr His 
            100                 105                 110         


Leu Leu Lys Asp Leu Glu Glu Gly Ile Gln Thr Leu Met Gly Arg Leu 
        115                 120                 125             


Glu Asp Gly Ser Arg Arg Thr Gly Gln Ile Leu Lys Gln Thr Tyr Ser 
    130                 135                 140                 


Lys Phe Asp Thr Asn Ser His Asn His Asp Ala Leu Leu Lys Asn Tyr 
145                 150                 155                 160 


Gly Leu Leu Tyr Cys Phe Arg Lys Asp Met Asp Lys Val Glu Thr Phe 
                165                 170                 175     


Leu Arg Met Val Gln Cys Arg Ser Val Glu Gly Ser Cys Gly Phe 
            180                 185                 190     


<210>  2406
<211>  122
<212>  PRT
<213>  Homo Sapiens

<400>  2406

Asn Asn Ile Tyr Trp Arg Glu Phe Ile Lys Leu His Tyr Leu Ser Pro 
1               5                   10                  15      


Ser Arg Glu Phe Lys Glu Tyr Lys Cys Asp Val Leu Met Arg Glu Lys 
            20                  25                  30          


Glu Ala Leu Lys Gly Lys Ser Phe His Met Phe Ile Tyr Ser Leu Trp 
        35                  40                  45              


Phe Lys Ile Gln Arg Ala Cys Ile Asn Glu Lys Gly Ser Asp Arg Tyr 
    50                  55                  60                  


Arg Asn Ala Tyr Val Trp Ala Pro Gly Ala Leu Lys Val Leu Glu Cys 
65                  70                  75                  80  


His Trp Glu Lys Tyr Asn Asn Arg Tyr Thr Glu Ser Arg Ser Phe Ser 
                85                  90                  95      


Tyr Ile Glu Phe His Cys Gly Val Asp Gly Tyr Val Asp Asn Ile Glu 
            100                 105                 110         


Asp Leu Arg Ile Ile Glu Pro Ile Ser Asn 
        115                 120         


<210>  2407
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2407

Glu Lys Thr Gly Val Cys Pro Glu Leu Gln Ala Asp Gln Asn Cys Thr 
1               5                   10                  15      


Gln Glu Cys Val Ser Asp Ser Glu Cys Ala Asp Asn Leu Lys Cys Cys 
            20                  25                  30          


Ser Ala Gly Cys Ala Thr Phe Cys Ser Leu Pro Asn Asp Lys Glu Gly 
        35                  40                  45              


Ser Cys Pro Gln Val Asn Ile Asn Phe Pro Gln Leu Gly Leu Cys Arg 
    50                  55                  60                  


Asp Gln Cys Gln Val Asp Ser Gln Cys Pro Gly Gln Met Lys Cys Cys 
65                  70                  75                  80  


Arg Asn Gly Cys Gly Lys Val Ser Cys Val Thr Pro Asn Phe 
                85                  90                  


<210>  2408
<211>  648
<212>  PRT
<213>  Homo Sapiens

<400>  2408

Ile Pro Thr Asn Ala Arg Leu Leu Ser Asp His Ser Lys Pro Thr Ala 
1               5                   10                  15      


Glu Thr Val Ala Ser Asp Asn Thr Ala Ile Pro Ser Leu Arg Ala Glu 
            20                  25                  30          


Ala Glu Glu Asn Glu Lys Glu Thr Ala Val Ser Thr Glu Asp Asp Ser 
        35                  40                  45              


His His Lys Ala Glu Lys Ser Ser Val Leu Lys Ser Lys Glu Glu Ser 
    50                  55                  60                  


His Glu Gln Ser Ala Glu Gln Gly Lys Ser Ser Ser Gln Glu Leu Gly 
65                  70                  75                  80  


Leu Lys Asp Gln Glu Asp Ser Asp Gly His Leu Ser Val Asn Leu Glu 
                85                  90                  95      


Tyr Ala Pro Thr Glu Gly Thr Ser Asp Ile Lys Glu Asp Met Ser Glu 
            100                 105                 110         


Pro Gln Glu Lys Lys Leu Ser Glu Asn Thr Asp Phe Leu Ala Pro Gly 
        115                 120                 125             


Val Ser Ser Phe Thr Asp Ser Asn Gln Gln Glu Ser Ile Thr Lys Arg 
    130                 135                 140                 


Glu Glu Asn Gln Glu Gln Pro Arg Asn Tyr Ser His His Gln Leu Asn 
145                 150                 155                 160 


Arg Ser Ser Lys His Ser Gln Gly Leu Arg Asp Gln Gly Asn Gln Glu 
                165                 170                 175     


Gln Asp Pro Asn Ile Ser Asn Gly Glu Glu Glu Glu Glu Lys Glu Pro 
            180                 185                 190         


Gly Glu Val Gly Thr His Asn Asp Asn Gln Glu Arg Lys Thr Glu Leu 
        195                 200                 205             


Pro Arg Glu His Ala Asn Ser Lys Gln Glu Glu Asp Asn Thr Gln Ser 
    210                 215                 220                 


Asp Asp Ile Leu Glu Glu Ser Asp Gln Pro Thr Gln Val Ser Lys Met 
225                 230                 235                 240 


Gln Glu Asp Glu Phe Asp Gln Gly Asn Gln Glu Gln Glu Asp Asn Ser 
                245                 250                 255     


Asn Ala Glu Met Glu Glu Glu Asn Ala Ser Asn Val Asn Lys His Ile 
            260                 265                 270         


Gln Glu Thr Glu Trp Gln Ser Gln Glu Gly Lys Thr Gly Leu Glu Ala 
        275                 280                 285             


Ile Ser Asn His Lys Glu Thr Glu Glu Lys Thr Val Ser Glu Ala Leu 
    290                 295                 300                 


Leu Met Glu Pro Thr Asp Asp Gly Asn Thr Thr Pro Arg Asn His Gly 
305                 310                 315                 320 


Val Asp Asp Asp Gly Asp Asp Asp Gly Asp Asp Gly Gly Thr Asp Gly 
                325                 330                 335     


Pro Arg His Ser Ala Ser Asp Asp Tyr Phe Ile Pro Ser Gln Ala Phe 
            340                 345                 350         


Leu Glu Ala Glu Arg Ala Gln Ser Ile Ala Tyr His Leu Lys Ile Glu 
        355                 360                 365             


Glu Gln Arg Glu Lys Val His Glu Asn Glu Asn Ile Gly Thr Thr Glu 
    370                 375                 380                 


Pro Gly Glu His Gln Glu Ala Lys Lys Ala Glu Asn Ser Ser Asn Glu 
385                 390                 395                 400 


Glu Glu Thr Ser Ser Glu Gly Asn Met Arg Val His Ala Val Asp Ser 
                405                 410                 415     


Cys Met Ser Phe Gln Cys Lys Arg Gly His Ile Cys Lys Ala Asp Gln 
            420                 425                 430         


Gln Gly Lys Pro His Cys Val Cys Gln Asp Pro Val Thr Cys Pro Pro 
        435                 440                 445             


Thr Lys Pro Leu Asp Gln Val Cys Gly Thr Asp Asn Gln Thr Tyr Ala 
    450                 455                 460                 


Ser Ser Cys His Leu Phe Ala Thr Lys Cys Arg Leu Glu Gly Thr Lys 
465                 470                 475                 480 


Lys Gly His Gln Leu Gln Leu Asp Tyr Phe Gly Ala Cys Lys Ser Ile 
                485                 490                 495     


Pro Thr Cys Thr Asp Phe Glu Val Ile Gln Phe Pro Leu Arg Met Arg 
            500                 505                 510         


Asp Trp Leu Lys Asn Ile Leu Met Gln Leu Tyr Glu Ala Asn Ser Glu 
        515                 520                 525             


His Ala Gly Tyr Leu Asn Glu Glu Gln Arg Asn Lys Val Lys Lys Ile 
    530                 535                 540                 


Tyr Leu Asp Glu Lys Arg Leu Leu Ala Gly Asp His Pro Ile Asp Leu 
545                 550                 555                 560 


Leu Leu Arg Asp Phe Lys Lys Asn Tyr His Met Tyr Val Tyr Pro Val 
                565                 570                 575     


His Trp Gln Phe Ser Glu Leu Asp Gln His Pro Met Asp Arg Val Leu 
            580                 585                 590         


Thr His Ser Glu Leu Ala Pro Leu Arg Ala Ser Leu Val Pro Met Glu 
        595                 600                 605             


His Cys Ile Thr Arg Phe Phe Glu Glu Cys Asp Pro Asn Lys Asp Lys 
    610                 615                 620                 


His Ile Thr Leu Lys Glu Trp Gly His Cys Phe Gly Ile Lys Glu Glu 
625                 630                 635                 640 


Asp Ile Asp Glu Asn Leu Leu Phe 
                645             


<210>  2409
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  2409

Ala Glu Gly Ser Pro Gly Thr Pro Asp Glu Ser Thr Pro Pro Pro Arg 
1               5                   10                  15      


Lys Lys Lys Lys Asp Ile Arg Asp Tyr Asn Asp Ala Asp Met Ala Arg 
            20                  25                  30          


Leu Leu Glu Gln Trp Glu Lys Asp Asp Asp Ile Glu Glu Gly Asp Leu 
        35                  40                  45              


Pro Glu His Lys Arg Pro Ser Ala Pro Val Asp Phe Ser Lys Ile Asp 
    50                  55                  60                  


Pro Ser Lys Pro Glu Ser Ile Leu Lys Met Thr Lys Lys Gly Lys Thr 
65                  70                  75                  80  


Leu Met Met Phe Val Thr Val Ser Gly Ser Pro Thr Glu Lys Glu Thr 
                85                  90                  95      


Glu Glu Ile Thr Ser Leu Trp Gln Gly Ser Leu Phe Asn Ala Asn Tyr 
            100                 105                 110         


Asp Val Gln Arg Phe Ile Val Gly Ser Asp Arg Ala Ile Phe Met Leu 
        115                 120                 125             


Arg Asp Gly Ser Tyr Ala Trp Glu Ile Lys Asp Phe Leu Val Gly Gln 
    130                 135                 140                 


Asp Arg Cys Ala Asp Val Thr Leu Glu Gly Gln Val Tyr Pro Gly Lys 
145                 150                 155                 160 


Gly Gly Gly Ser Lys Glu Lys Asn Lys Thr Lys Gln Asp Lys Gly Lys 
                165                 170                 175     


Lys Lys Lys Glu Gly Asp Leu Lys Ser Arg Ser Ser Lys Glu Glu Asn 
            180                 185                 190         


Arg Ala Gly Asn Lys Arg Glu Asp Leu 
        195                 200     


<210>  2410
<211>  50
<212>  PRT
<213>  Homo Sapiens

<400>  2410

Ala His His Tyr Ser Gln Leu Thr Gln Phe Thr Cys Glu Thr Thr Leu 
1               5                   10                  15      


Asp Ser Cys Gln Cys Lys Leu Pro Ser Ser Glu Pro Leu Ser Arg Thr 
            20                  25                  30          


Phe Val Tyr Arg Asp Val Thr Asp Cys Thr Ser Val Thr Gly Thr Phe 
        35                  40                  45              


Lys Leu 
    50  


<210>  2411
<211>  554
<212>  PRT
<213>  Homo Sapiens

<400>  2411

Leu Gly Asp His Asn Phe Leu Arg Arg Glu Ile Lys Ile Glu Gly Asp 
1               5                   10                  15      


Leu Val Leu Gly Gly Leu Phe Pro Ile Asn Glu Lys Gly Thr Gly Thr 
            20                  25                  30          


Glu Glu Cys Gly Arg Ile Asn Glu Asp Arg Gly Ile Gln Arg Leu Glu 
        35                  40                  45              


Ala Met Leu Phe Ala Ile Asp Glu Ile Asn Lys Asp Asp Tyr Leu Leu 
    50                  55                  60                  


Pro Gly Val Lys Leu Gly Val His Ile Leu Asp Thr Cys Ser Arg Asp 
65                  70                  75                  80  


Thr Tyr Ala Leu Glu Gln Ser Leu Glu Phe Val Arg Ala Ser Leu Thr 
                85                  90                  95      


Lys Val Asp Glu Ala Glu Tyr Met Cys Pro Asp Gly Ser Tyr Ala Ile 
            100                 105                 110         


Gln Glu Asn Ile Pro Leu Leu Ile Ala Gly Val Ile Gly Gly Ser Tyr 
        115                 120                 125             


Ser Ser Val Ser Ile Gln Val Ala Asn Leu Leu Arg Leu Phe Gln Ile 
    130                 135                 140                 


Pro Gln Ile Ser Tyr Ala Ser Thr Ser Ala Lys Leu Ser Asp Lys Ser 
145                 150                 155                 160 


Arg Tyr Asp Tyr Phe Ala Arg Thr Val Pro Pro Asp Phe Tyr Gln Ala 
                165                 170                 175     


Lys Ala Met Ala Glu Ile Leu Arg Phe Phe Asn Trp Thr Tyr Val Ser 
            180                 185                 190         


Thr Val Ala Ser Glu Gly Asp Tyr Gly Glu Thr Gly Ile Glu Ala Phe 
        195                 200                 205             


Glu Gln Glu Ala Arg Leu Arg Asn Ile Cys Ile Ala Thr Ala Glu Lys 
    210                 215                 220                 


Val Gly Arg Ser Asn Ile Arg Lys Ser Tyr Asp Ser Val Ile Arg Glu 
225                 230                 235                 240 


Leu Leu Gln Lys Pro Asn Ala Arg Val Val Val Leu Phe Met Arg Ser 
                245                 250                 255     


Asp Asp Ser Arg Glu Leu Ile Ala Ala Ala Ser Arg Ala Asn Ala Ser 
            260                 265                 270         


Phe Thr Trp Val Ala Ser Asp Gly Trp Gly Ala Gln Glu Ser Ile Ile 
        275                 280                 285             


Lys Gly Ser Glu His Val Ala Tyr Gly Ala Ile Thr Leu Glu Leu Ala 
    290                 295                 300                 


Ser Gln Pro Val Arg Gln Phe Asp Arg Tyr Phe Gln Ser Leu Asn Pro 
305                 310                 315                 320 


Tyr Asn Asn His Arg Asn Pro Trp Phe Arg Asp Phe Trp Glu Gln Lys 
                325                 330                 335     


Phe Gln Cys Ser Leu Gln Asn Lys Arg Asn His Arg Arg Val Cys Asp 
            340                 345                 350         


Lys His Leu Ala Ile Asp Ser Ser Asn Tyr Glu Gln Glu Ser Lys Ile 
        355                 360                 365             


Met Phe Val Val Asn Ala Val Tyr Ala Met Ala His Ala Leu His Lys 
    370                 375                 380                 


Met Gln Arg Thr Leu Cys Pro Asn Thr Thr Lys Leu Cys Asp Ala Met 
385                 390                 395                 400 


Lys Ile Leu Asp Gly Lys Lys Leu Tyr Lys Asp Tyr Leu Leu Lys Ile 
                405                 410                 415     


Asn Phe Thr Ala Pro Phe Asn Thr Asn Lys Asp Ala Asp Ser Ile Val 
            420                 425                 430         


Lys Phe Asp Thr Phe Gly Asp Gly Met Gly Arg Tyr Asn Val Phe Asn 
        435                 440                 445             


Phe Gln Asn Val Gly Gly Lys Tyr Ser Tyr Leu Lys Val Gly His Trp 
    450                 455                 460                 


Ala Glu Thr Leu Ser Leu Asp Val Asn Ser Ile His Trp Ser Arg Asn 
465                 470                 475                 480 


Ser Val Pro Thr Ser Gln Cys Ser Asp Ala Cys Ala Pro Asn Glu Met 
                485                 490                 495     


Lys Asn Met Gln Pro Gly Asp Val Cys Cys Trp Ile Cys Ile Pro Cys 
            500                 505                 510         


Glu Pro Tyr Glu Tyr Leu Ala Asp Glu Phe Thr Cys Met Asp Cys Gly 
        515                 520                 525             


Ser Gly Gln Trp Pro Thr Ala Asp Leu Thr Gly Cys Tyr Asp Leu Pro 
    530                 535                 540                 


Glu Asp Tyr Ile Arg Trp Glu Asp Ala Trp 
545                 550                 


<210>  2412
<211>  1119
<212>  PRT
<213>  Homo Sapiens

<400>  2412

Val Thr Val Arg Asp Lys Thr Glu Glu Ser Cys Pro Ile Leu Arg Ile 
1               5                   10                  15      


Glu Gly His Gln Leu Thr Tyr Asp Asn Ile Asn Lys Leu Glu Val Ser 
            20                  25                  30          


Gly Phe Asp Leu Gly Asp Ser Phe Ser Leu Arg Arg Ala Phe Cys Glu 
        35                  40                  45              


Ser Asp Lys Thr Cys Phe Lys Leu Gly Ser Ala Leu Leu Ile Arg Asp 
    50                  55                  60                  


Thr Ile Lys Ile Phe Pro Lys Gly Leu Pro Glu Glu Tyr Ser Val Ala 
65                  70                  75                  80  


Ala Met Phe Arg Val Arg Arg Asn Ala Lys Lys Glu Arg Trp Phe Leu 
                85                  90                  95      


Trp Gln Val Leu Asn Gln Gln Asn Ile Pro Gln Ile Ser Ile Val Val 
            100                 105                 110         


Asp Gly Gly Lys Lys Val Val Glu Phe Met Phe Gln Ala Thr Glu Gly 
        115                 120                 125             


Asp Val Leu Asn Tyr Ile Phe Arg Asn Arg Glu Leu Arg Pro Leu Phe 
    130                 135                 140                 


Asp Arg Gln Trp His Lys Leu Gly Ile Ser Ile Gln Ser Gln Val Ile 
145                 150                 155                 160 


Ser Leu Tyr Met Asp Cys Asn Leu Ile Ala Arg Arg Gln Thr Asp Glu 
                165                 170                 175     


Lys Asp Thr Val Asp Phe His Gly Arg Thr Val Ile Ala Thr Arg Ala 
            180                 185                 190         


Ser Asp Gly Lys Pro Val Asp Ile Glu Leu His Gln Leu Lys Ile Tyr 
        195                 200                 205             


Cys Ser Ala Asn Leu Ile Ala Gln Glu Thr Cys Cys Glu Ile Ser Asp 
    210                 215                 220                 


Thr Lys Cys Pro Glu Gln Asp Gly Phe Gly Asn Ile Ala Ser Ser Trp 
225                 230                 235                 240 


Val Thr Ala His Ala Ser Lys Met Ser Ser Tyr Leu Pro Ala Lys Gln 
                245                 250                 255     


Glu Leu Lys Asp Gln Cys Gln Cys Ile Pro Asn Lys Gly Glu Ala Gly 
            260                 265                 270         


Leu Pro Gly Ala Pro Gly Ser Pro Gly Gln Lys Gly His Lys Gly Glu 
        275                 280                 285             


Pro Gly Glu Asn Gly Leu His Gly Ala Pro Gly Phe Pro Gly Gln Lys 
    290                 295                 300                 


Gly Glu Gln Gly Phe Glu Gly Ser Lys Gly Glu Thr Gly Glu Lys Gly 
305                 310                 315                 320 


Glu Gln Gly Glu Lys Gly Asp Pro Ala Leu Ala Gly Leu Asn Gly Glu 
                325                 330                 335     


Asn Gly Leu Lys Gly Asp Leu Gly Pro His Gly Pro Pro Gly Pro Lys 
            340                 345                 350         


Gly Glu Lys Gly Asp Thr Gly Pro Pro Gly Pro Pro Ala Leu Pro Gly 
        355                 360                 365             


Ser Leu Gly Ile Gln Gly Pro Gln Gly Pro Pro Gly Lys Glu Gly Gln 
    370                 375                 380                 


Arg Gly Arg Arg Gly Lys Thr Gly Pro Pro Gly Lys Pro Gly Pro Pro 
385                 390                 395                 400 


Gly Pro Pro Gly Pro Pro Gly Ile Gln Gly Ile His Gln Thr Leu Gly 
                405                 410                 415     


Gly Tyr Tyr Asn Lys Asp Asn Lys Gly Asn Asp Glu His Glu Ala Gly 
            420                 425                 430         


Gly Leu Lys Gly Asp Lys Gly Glu Thr Gly Leu Pro Gly Phe Pro Gly 
        435                 440                 445             


Ser Val Gly Pro Lys Gly Gln Lys Gly Glu Pro Gly Glu Pro Phe Thr 
    450                 455                 460                 


Lys Gly Glu Lys Gly Asp Arg Gly Glu Pro Gly Val Ile Gly Ser Gln 
465                 470                 475                 480 


Gly Val Lys Gly Glu Pro Gly Asp Pro Gly Pro Pro Gly Leu Ile Gly 
                485                 490                 495     


Ser Pro Gly Leu Lys Gly Gln Gln Gly Ser Ala Gly Ser Met Gly Pro 
            500                 505                 510         


Arg Gly Pro Pro Gly Asp Val Gly Leu Pro Gly Glu His Gly Ile Pro 
        515                 520                 525             


Gly Lys Gln Gly Ile Lys Gly Glu Lys Gly Asp Pro Gly Gly Ile Ile 
    530                 535                 540                 


Gly Pro Pro Gly Leu Pro Gly Pro Lys Gly Glu Ala Gly Pro Pro Gly 
545                 550                 555                 560 


Lys Ser Leu Pro Gly Glu Pro Gly Leu Asp Gly Asn Pro Gly Ala Pro 
                565                 570                 575     


Gly Pro Arg Gly Pro Lys Gly Glu Arg Gly Leu Pro Gly Val His Gly 
            580                 585                 590         


Ser Pro Gly Asp Ile Gly Pro Gln Gly Ile Gly Ile Pro Gly Arg Thr 
        595                 600                 605             


Gly Ala Gln Gly Pro Ala Gly Glu Pro Gly Ile Gln Gly Pro Arg Gly 
    610                 615                 620                 


Leu Pro Gly Leu Pro Gly Thr Pro Gly Thr Pro Gly Asn Asp Gly Val 
625                 630                 635                 640 


Pro Gly Arg Asp Gly Lys Pro Gly Leu Pro Gly Pro Pro Gly Asp Pro 
                645                 650                 655     


Ile Ala Leu Pro Leu Leu Gly Asp Ile Gly Ala Leu Leu Lys Asn Phe 
            660                 665                 670         


Cys Gly Asn Cys Gln Ala Ser Val Pro Gly Leu Lys Ser Asn Lys Gly 
        675                 680                 685             


Glu Glu Gly Gly Ala Gly Glu Pro Gly Lys Tyr Asp Ser Met Ala Arg 
    690                 695                 700                 


Lys Gly Asp Ile Gly Pro Arg Gly Pro Pro Gly Ile Pro Gly Arg Glu 
705                 710                 715                 720 


Gly Pro Lys Gly Ser Lys Gly Glu Arg Gly Tyr Pro Gly Ile Pro Gly 
                725                 730                 735     


Glu Lys Gly Asp Glu Gly Leu Gln Gly Ile Pro Gly Ile Pro Gly Ala 
            740                 745                 750         


Pro Gly Pro Thr Gly Pro Pro Gly Leu Met Gly Arg Thr Gly His Pro 
        755                 760                 765             


Gly Pro Thr Gly Ala Lys Gly Glu Lys Gly Ser Asp Gly Pro Pro Gly 
    770                 775                 780                 


Lys Pro Gly Pro Pro Gly Pro Pro Gly Ile Pro Phe Asn Glu Arg Asn 
785                 790                 795                 800 


Gly Met Ser Ser Leu Tyr Lys Ile Lys Gly Gly Val Asn Val Pro Ser 
                805                 810                 815     


Tyr Pro Gly Pro Pro Gly Pro Pro Gly Pro Lys Gly Asp Pro Gly Pro 
            820                 825                 830         


Val Gly Glu Pro Gly Ala Met Gly Leu Pro Gly Leu Glu Gly Phe Pro 
        835                 840                 845             


Gly Val Lys Gly Asp Arg Gly Pro Ala Gly Pro Pro Gly Ile Ala Gly 
    850                 855                 860                 


Met Ser Gly Lys Pro Gly Ala Pro Gly Pro Pro Gly Val Pro Gly Glu 
865                 870                 875                 880 


Pro Gly Glu Arg Gly Pro Val Gly Asp Ile Gly Phe Pro Gly Pro Glu 
                885                 890                 895     


Gly Pro Ser Gly Lys Pro Gly Ile Asn Gly Lys Asp Gly Ile Pro Gly 
            900                 905                 910         


Ala Gln Gly Ile Met Gly Lys Pro Gly Asp Arg Gly Pro Lys Gly Glu 
        915                 920                 925             


Arg Gly Asp Gln Gly Ile Pro Gly Asp Arg Gly Ser Gln Gly Glu Arg 
    930                 935                 940                 


Gly Lys Pro Gly Leu Thr Gly Met Lys Gly Ala Ile Gly Pro Met Gly 
945                 950                 955                 960 


Pro Pro Gly Asn Lys Gly Ser Met Gly Ser Pro Gly His Gln Gly Pro 
                965                 970                 975     


Pro Gly Ser Pro Gly Ile Pro Gly Ile Pro Ala Asp Ala Val Ser Phe 
            980                 985                 990         


Glu Glu Ile Lys Lys Tyr Ile Asn  Gln Glu Val Leu Arg  Ile Phe Glu 
        995                 1000                 1005             


Glu Arg  Met Ala Val Phe Leu  Ser Gln Leu Lys Leu  Pro Ala Ala 
    1010                 1015                 1020             


Met Leu  Ala Ala Gln Ala Tyr  Gly Arg Pro Gly Pro  Pro Gly Lys 
    1025                 1030                 1035             


Asp Gly  Leu Pro Gly Pro Pro  Gly Asp Pro Gly Pro  Gln Gly Tyr 
    1040                 1045                 1050             


Arg Gly  Gln Lys Gly Glu Arg  Gly Glu Pro Gly Ile  Gly Leu Pro 
    1055                 1060                 1065             


Gly Ser  Pro Gly Leu Pro Gly  Thr Ser Ala Leu Gly  Leu Pro Gly 
    1070                 1075                 1080             


Ser Pro  Gly Ala Pro Gly Pro  Gln Gly Pro Pro Gly  Pro Ser Gly 
    1085                 1090                 1095             


Arg Cys  Asn Pro Glu Asp Cys  Leu Tyr Pro Val Ser  His Ala His 
    1100                 1105                 1110             


Gln Arg  Thr Gly Gly Asn 
    1115                 


<210>  2413
<211>  885
<212>  PRT
<213>  Homo Sapiens

<400>  2413

Arg Gly Ile Leu Glu Ser Ile Gln Arg Phe Ser Leu Leu Pro Thr Tyr 
1               5                   10                  15      


Leu Pro Val Thr Tyr His Ile Asn Asn Ala Asp Val Ser Phe Phe Leu 
            20                  25                  30          


Lys Glu Ala Asn Gln Asp Ile Met Arg Asn Ser Ser Leu Gln Ser Arg 
        35                  40                  45              


Val Glu Ser Phe Leu Ile Tyr Lys Ser Arg Arg Leu Pro Val Leu Asn 
    50                  55                  60                  


Ala Ser Tyr Gly Pro Phe Ser Ile Glu Gln Val Val Pro Gln Asp Leu 
65                  70                  75                  80  


Met Leu Pro Ser Asn Pro Phe Gly Phe Thr Asn Lys Phe Ser Leu Asn 
                85                  90                  95      


Trp Lys Leu Lys Ala His Ile Leu Arg Asp Lys Val Tyr Leu Ser Arg 
            100                 105                 110         


Pro Lys Val Gln Val Leu Phe His Ile Met Gly Arg Asp Trp Asp Asp 
        115                 120                 125             


Arg Ser Ala Gly Glu Lys Leu Pro Cys Leu Arg Val Phe Ala Phe Arg 
    130                 135                 140                 


Glu Thr Arg Glu Val Arg Gly Ser Cys Arg Leu Gln Gly Asp Leu Gly 
145                 150                 155                 160 


Leu Cys Val Ala Glu Leu Glu Leu Leu Ser Ser Trp Phe Ser Pro Pro 
                165                 170                 175     


Thr Val Val Ala Gly Arg Arg Lys Ser Val Asp Gln Pro Glu Gly Thr 
            180                 185                 190         


Pro Val Glu Leu Tyr Tyr Thr Val His Pro Gly Gly Glu Arg Gly Asp 
        195                 200                 205             


Cys Val Arg Glu Asp Ala Arg Arg Ser Asn Gly Ile Arg Thr Gly His 
    210                 215                 220                 


Ser Asp Ile Asp Glu Ser Gly Pro Pro Leu Gln Arg Ile Gly Ser Ile 
225                 230                 235                 240 


Phe Leu Tyr Gln Thr His Arg Lys Pro Ser Leu Arg Glu Leu Arg Leu 
                245                 250                 255     


Asp Asn Ser Val Ala Ile His Tyr Ile Pro Lys Thr Val Arg Lys Gly 
            260                 265                 270         


Asp Val Leu Thr Phe Pro Val Ser Ile Ser Arg Asn Ser Thr Glu Asp 
        275                 280                 285             


Arg Phe Thr Leu Arg Ala Lys Val Lys Lys Gly Val Asn Ile Ile Gly 
    290                 295                 300                 


Val Arg Ala Ser Ser Pro Ser Ile Trp Asp Val Lys Glu Arg Thr Asp 
305                 310                 315                 320 


Tyr Thr Gly Lys Tyr Ala Pro Ala Val Ile Val Cys Gln Lys Lys Ala 
                325                 330                 335     


Ala Gly Ser Glu Asn Ser Ala Asp Gly Ala Ser Tyr Glu Val Met Gln 
            340                 345                 350         


Ile Asp Val Glu Val Glu Glu Pro Gly Asp Leu Pro Ala Thr Gln Leu 
        355                 360                 365             


Val Thr Trp Gln Val Glu Tyr Pro Gly Glu Ile Thr Ser Asp Leu Gly 
    370                 375                 380                 


Val Ser Lys Ile Tyr Val Ser Pro Lys Asp Leu Ile Gly Val Val Pro 
385                 390                 395                 400 


Leu Ala Met Glu Ala Glu Ile Leu Asn Thr Ala Ile Leu Thr Gly Lys 
                405                 410                 415     


Thr Val Ala Val Pro Val Lys Val Val Ser Val Glu Asp Asp Gly Thr 
            420                 425                 430         


Val Thr Glu Leu Leu Glu Ser Val Glu Cys Arg Ser Ser Asp Glu Asp 
        435                 440                 445             


Val Ile Lys Val Ser Asp Arg Cys Asp Tyr Val Phe Val Asn Gly Lys 
    450                 455                 460                 


Glu Met Lys Gly Lys Val Asn Val Val Val Asn Phe Thr Tyr Gln His 
465                 470                 475                 480 


Leu Ser Ser Pro Leu Glu Met Thr Val Trp Val Pro Arg Leu Pro Leu 
                485                 490                 495     


Gln Ile Glu Val Ser Asp Thr Glu Leu Asn Gln Ile Lys Gly Trp Arg 
            500                 505                 510         


Val Pro Ile Val Ser Ser Arg Arg Pro Ala Gly Asp Ser Glu Glu Glu 
        515                 520                 525             


Glu Asp Asp Glu Arg Arg Gly Arg Gly Cys Thr Leu Gln Tyr Gln His 
    530                 535                 540                 


Ala Met Val Arg Val Leu Thr Gln Phe Val Ala Glu Ala Ala Gly Pro 
545                 550                 555                 560 


Gly Gly His Leu Ala His Leu Leu Gly Ser Asp Trp Gln Val Asp Ile 
                565                 570                 575     


Thr Glu Leu Ile Asn Asp Phe Met Gln Val Glu Glu Pro Arg Ile Ala 
            580                 585                 590         


Lys Leu Gln Gly Gly Gln Ile Leu Met Gly Gln Glu Leu Gly Met Thr 
        595                 600                 605             


Thr Ile Gln Ile Leu Ser Pro Leu Ser Asp Thr Ile Leu Ala Glu Lys 
    610                 615                 620                 


Thr Ile Thr Val Leu Asp Glu Lys Val Thr Ile Thr Asp Leu Gly Val 
625                 630                 635                 640 


Gln Leu Val Thr Gly Leu Ser Leu Ser Leu Gln Leu Ser Pro Gly Ser 
                645                 650                 655     


Asn Arg Ala Ile Phe Ala Thr Ala Val Ala Gln Glu Leu Leu Gln Arg 
            660                 665                 670         


Pro Lys Gln Glu Ala Ala Ile Ser Cys Trp Val Gln Phe Ser Asp Gly 
        675                 680                 685             


Ser Val Thr Pro Leu Asp Ile Tyr Asp Gly Lys Asp Phe Ser Leu Met 
    690                 695                 700                 


Ala Thr Ser Leu Asp Glu Lys Val Val Ser Ile His Gln Asp Pro Lys 
705                 710                 715                 720 


Phe Lys Trp Pro Ile Ile Ala Ala Glu Thr Glu Gly Gln Gly Thr Leu 
                725                 730                 735     


Val Lys Val Glu Met Val Ile Ser Glu Ser Cys Gln Lys Ser Lys Arg 
            740                 745                 750         


Lys Ser Val Leu Ala Val Gly Thr Ala Asn Ile Lys Val Lys Phe Gly 
        755                 760                 765             


Gln Asn Asp Ala Asn Pro Asn Thr Ser Asp Ser Arg His Thr Gly Ala 
    770                 775                 780                 


Gly Val His Met Glu Asn Asn Val Ser Asp Arg Arg Pro Lys Lys Pro 
785                 790                 795                 800 


Leu Gln Glu Trp Gly Ser Gln Glu Gly Gln Tyr Tyr Gly Ser Ser Ser 
                805                 810                 815     


Met Gly Leu Met Glu Gly Arg Gly Thr Thr Thr Asp Arg Ser Ile Leu 
            820                 825                 830         


Gln Lys Lys Lys Gly Gln Glu Ser Leu Leu Asp Asp Asn Ser His Leu 
        835                 840                 845             


Gln Thr Ile Pro Ser Asp Leu Thr Ser Phe Pro Ala Gln Val Asp Leu 
    850                 855                 860                 


Pro Arg Ser Asn Gly Glu Met Asp Gly Asn Asp Leu Met Gln Ala Ser 
865                 870                 875                 880 


Lys Gly Leu Ser Asp 
                885 


<210>  2414
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2414

Ser Ser Pro Gly Ala Pro Ala Ile Ser Ala Ala Ser Phe Leu Gln Asp 
1               5                   10                  15      


Leu Ile His Arg Tyr Gly Glu Gly Asp Ser Leu Thr Leu Gln Gln Leu 
            20                  25                  30          


Lys Ala Leu Leu Asn His Leu Asp Val Gly Val Gly Arg Gly Asn Val 
        35                  40                  45              


Thr Gln His Val Gln Gly His Arg Asn Leu Ser Thr Cys Phe Ser Ser 
    50                  55                  60                  


Gly Asp Leu Phe Thr Ala His Asn Phe Ser Glu Gln Ser Arg Ile Gly 
65                  70                  75                  80  


Ser Ser Glu Leu Gln Glu Phe Cys Pro Thr Ile Leu Gln Gln Leu Asp 
                85                  90                  95      


Ser Arg Ala Cys Thr Ser Glu Asn Gln Glu Asn Glu Glu Asn Glu Gln 
            100                 105                 110         


Thr Glu Glu Gly Arg Pro Ser Ala Val Glu Val Trp Gly Tyr Gly 
        115                 120                 125         


<210>  2415
<211>  596
<212>  PRT
<213>  Homo Sapiens

<400>  2415

Ala Ala Val Gln Ala Ala Glu Val Lys Val Asp Gly Ser Glu Pro Lys 
1               5                   10                  15      


Leu Ser Lys Asn Glu Leu Lys Arg Arg Leu Lys Ala Glu Lys Lys Val 
            20                  25                  30          


Ala Glu Lys Glu Ala Lys Gln Lys Glu Leu Ser Glu Lys Gln Leu Ser 
        35                  40                  45              


Gln Ala Thr Ala Ala Ala Thr Asn His Thr Thr Asp Asn Gly Val Gly 
    50                  55                  60                  


Pro Glu Glu Glu Ser Val Asp Pro Asn Gln Tyr Tyr Lys Ile Arg Ser 
65                  70                  75                  80  


Gln Ala Ile His Gln Leu Lys Val Asn Gly Glu Asp Pro Tyr Pro His 
                85                  90                  95      


Lys Phe His Val Asp Ile Ser Leu Thr Asp Phe Ile Gln Lys Tyr Ser 
            100                 105                 110         


His Leu Gln Pro Gly Asp His Leu Thr Asp Ile Thr Leu Lys Val Ala 
        115                 120                 125             


Gly Arg Ile His Ala Lys Arg Ala Ser Gly Gly Lys Leu Ile Phe Tyr 
    130                 135                 140                 


Asp Leu Arg Gly Glu Gly Val Lys Leu Gln Val Met Ala Asn Ser Arg 
145                 150                 155                 160 


Asn Tyr Lys Ser Glu Glu Glu Phe Ile His Ile Asn Asn Lys Leu Arg 
                165                 170                 175     


Arg Gly Asp Ile Ile Gly Val Gln Gly Asn Pro Gly Lys Thr Lys Lys 
            180                 185                 190         


Gly Glu Leu Ser Ile Ile Pro Tyr Glu Ile Thr Leu Leu Ser Pro Cys 
        195                 200                 205             


Leu His Met Leu Pro His Leu His Phe Gly Leu Lys Asp Lys Glu Thr 
    210                 215                 220                 


Arg Tyr Arg Gln Arg Tyr Leu Asp Leu Ile Leu Asn Asp Phe Val Arg 
225                 230                 235                 240 


Gln Lys Phe Ile Ile Arg Ser Lys Ile Ile Thr Tyr Ile Arg Ser Phe 
                245                 250                 255     


Leu Asp Glu Leu Gly Phe Leu Glu Ile Glu Thr Pro Met Met Asn Ile 
            260                 265                 270         


Ile Pro Gly Gly Ala Val Ala Lys Pro Phe Ile Thr Tyr His Asn Glu 
        275                 280                 285             


Leu Asp Met Asn Leu Tyr Met Arg Ile Ala Pro Glu Leu Tyr His Lys 
    290                 295                 300                 


Met Leu Val Val Gly Gly Ile Asp Arg Val Tyr Glu Ile Gly Arg Gln 
305                 310                 315                 320 


Phe Arg Asn Glu Gly Ile Asp Leu Thr His Asn Pro Glu Phe Thr Thr 
                325                 330                 335     


Cys Glu Phe Tyr Met Ala Tyr Ala Asp Tyr His Asp Leu Met Glu Ile 
            340                 345                 350         


Thr Glu Lys Met Val Ser Gly Met Val Lys His Ile Thr Gly Ser Tyr 
        355                 360                 365             


Lys Val Thr Tyr His Pro Asp Gly Pro Glu Gly Gln Ala Tyr Asp Val 
    370                 375                 380                 


Asp Phe Thr Pro Pro Phe Arg Arg Ile Asn Met Val Glu Glu Leu Glu 
385                 390                 395                 400 


Lys Ala Leu Gly Met Lys Leu Pro Glu Thr Asn Leu Phe Glu Thr Glu 
                405                 410                 415     


Glu Thr Arg Lys Ile Leu Asp Asp Ile Cys Val Ala Lys Ala Val Glu 
            420                 425                 430         


Cys Pro Pro Pro Arg Thr Thr Ala Arg Leu Leu Asp Lys Leu Val Gly 
        435                 440                 445             


Glu Phe Leu Glu Val Thr Cys Ile Asn Pro Thr Phe Ile Cys Asp His 
    450                 455                 460                 


Pro Gln Ile Met Ser Pro Leu Ala Lys Trp His Arg Ser Lys Glu Gly 
465                 470                 475                 480 


Leu Thr Glu Arg Phe Glu Leu Phe Val Met Lys Lys Glu Ile Cys Asn 
                485                 490                 495     


Ala Tyr Thr Glu Leu Asn Asp Pro Met Arg Gln Arg Gln Leu Phe Glu 
            500                 505                 510         


Glu Gln Ala Lys Ala Lys Ala Ala Gly Asp Asp Glu Ala Met Phe Ile 
        515                 520                 525             


Asp Glu Asn Phe Cys Thr Ala Leu Glu Tyr Gly Leu Pro Pro Thr Ala 
    530                 535                 540                 


Gly Trp Gly Met Gly Ile Asp Arg Val Ala Met Phe Leu Thr Asp Ser 
545                 550                 555                 560 


Asn Asn Ile Lys Glu Val Leu Leu Phe Pro Ala Met Lys Pro Glu Asp 
                565                 570                 575     


Lys Lys Glu Asn Val Ala Thr Thr Asp Thr Leu Glu Ser Thr Thr Val 
            580                 585                 590         


Gly Thr Ser Val 
        595     


<210>  2416
<211>  758
<212>  PRT
<213>  Homo Sapiens

<400>  2416

Asn Asn His Tyr Asp Lys Ile Leu Ala His Ser Arg Ile Arg Gly Arg 
1               5                   10                  15      


Asp Gln Gly Pro Asn Val Cys Ala Leu Gln Gln Ile Leu Gly Thr Lys 
            20                  25                  30          


Lys Lys Tyr Phe Ser Thr Cys Lys Asn Trp Tyr Lys Lys Ser Ile Cys 
        35                  40                  45              


Gly Gln Lys Thr Thr Val Leu Tyr Glu Cys Cys Pro Gly Tyr Met Arg 
    50                  55                  60                  


Met Glu Gly Met Lys Gly Cys Pro Ala Val Leu Pro Ile Asp His Val 
65                  70                  75                  80  


Tyr Gly Thr Leu Gly Ile Val Gly Ala Thr Thr Thr Gln Arg Tyr Ser 
                85                  90                  95      


Asp Ala Ser Lys Leu Arg Glu Glu Ile Glu Gly Lys Gly Ser Phe Thr 
            100                 105                 110         


Tyr Phe Ala Pro Ser Asn Glu Ala Trp Asp Asn Leu Asp Ser Asp Ile 
        115                 120                 125             


Arg Arg Gly Leu Glu Ser Asn Val Asn Val Glu Leu Leu Asn Ala Leu 
    130                 135                 140                 


His Ser His Met Ile Asn Lys Arg Met Leu Thr Lys Asp Leu Lys Asn 
145                 150                 155                 160 


Gly Met Ile Ile Pro Ser Met Tyr Asn Asn Leu Gly Leu Phe Ile Asn 
                165                 170                 175     


His Tyr Pro Asn Gly Val Val Thr Val Asn Cys Ala Arg Ile Ile His 
            180                 185                 190         


Gly Asn Gln Ile Ala Thr Asn Gly Val Val His Val Ile Asp Arg Val 
        195                 200                 205             


Leu Thr Gln Ile Gly Thr Ser Ile Gln Asp Phe Ile Glu Ala Glu Asp 
    210                 215                 220                 


Asp Leu Ser Ser Phe Arg Ala Ala Ala Ile Thr Ser Asp Ile Leu Glu 
225                 230                 235                 240 


Ala Leu Gly Arg Asp Gly His Phe Thr Leu Phe Ala Pro Thr Asn Glu 
                245                 250                 255     


Ala Phe Glu Lys Leu Pro Arg Gly Val Leu Glu Arg Ile Met Gly Asp 
            260                 265                 270         


Lys Val Ala Ser Glu Ala Leu Met Lys Tyr His Ile Leu Asn Thr Leu 
        275                 280                 285             


Gln Cys Ser Glu Ser Ile Met Gly Gly Ala Val Phe Glu Thr Leu Glu 
    290                 295                 300                 


Gly Asn Thr Ile Glu Ile Gly Cys Asp Gly Asp Ser Ile Thr Val Asn 
305                 310                 315                 320 


Gly Ile Lys Met Val Asn Lys Lys Asp Ile Val Thr Asn Asn Gly Val 
                325                 330                 335     


Ile His Leu Ile Asp Gln Val Leu Ile Pro Asp Ser Ala Lys Gln Val 
            340                 345                 350         


Ile Glu Leu Ala Gly Lys Gln Gln Thr Thr Phe Thr Asp Leu Val Ala 
        355                 360                 365             


Gln Leu Gly Leu Ala Ser Ala Leu Arg Pro Asp Gly Glu Tyr Thr Leu 
    370                 375                 380                 


Leu Ala Pro Val Asn Asn Ala Phe Ser Asp Asp Thr Leu Ser Met Asp 
385                 390                 395                 400 


Gln Arg Leu Leu Lys Leu Ile Leu Gln Asn His Ile Leu Lys Val Lys 
                405                 410                 415     


Val Gly Leu Asn Glu Leu Tyr Asn Gly Gln Ile Leu Glu Thr Ile Gly 
            420                 425                 430         


Gly Lys Gln Leu Arg Val Phe Val Tyr Arg Thr Ala Val Cys Ile Glu 
        435                 440                 445             


Asn Ser Cys Met Glu Lys Gly Ser Lys Gln Gly Arg Asn Gly Ala Ile 
    450                 455                 460                 


His Ile Phe Arg Glu Ile Ile Lys Pro Ala Glu Lys Ser Leu His Glu 
465                 470                 475                 480 


Lys Leu Lys Gln Asp Lys Arg Phe Ser Thr Phe Leu Ser Leu Leu Glu 
                485                 490                 495     


Ala Ala Asp Leu Lys Glu Leu Leu Thr Gln Pro Gly Asp Trp Thr Leu 
            500                 505                 510         


Phe Val Pro Thr Asn Asp Ala Phe Lys Gly Met Thr Ser Glu Glu Lys 
        515                 520                 525             


Glu Ile Leu Ile Arg Asp Lys Asn Ala Leu Gln Asn Ile Ile Leu Tyr 
    530                 535                 540                 


His Leu Thr Pro Gly Val Phe Ile Gly Lys Gly Phe Glu Pro Gly Val 
545                 550                 555                 560 


Thr Asn Ile Leu Lys Thr Thr Gln Gly Ser Lys Ile Phe Leu Lys Glu 
                565                 570                 575     


Val Asn Asp Thr Leu Leu Val Asn Glu Leu Lys Ser Lys Glu Ser Asp 
            580                 585                 590         


Ile Met Thr Thr Asn Gly Val Ile His Val Val Asp Lys Leu Leu Tyr 
        595                 600                 605             


Pro Ala Asp Thr Pro Val Gly Asn Asp Gln Leu Leu Glu Ile Leu Asn 
    610                 615                 620                 


Lys Leu Ile Lys Tyr Ile Gln Ile Lys Phe Val Arg Gly Ser Thr Phe 
625                 630                 635                 640 


Lys Glu Ile Pro Val Thr Val Tyr Lys Pro Ile Ile Lys Lys Tyr Thr 
                645                 650                 655     


Lys Ile Ile Asp Gly Val Pro Val Glu Ile Thr Glu Lys Glu Thr Arg 
            660                 665                 670         


Glu Glu Arg Ile Ile Thr Gly Pro Glu Ile Lys Tyr Thr Arg Ile Ser 
        675                 680                 685             


Thr Gly Gly Gly Glu Thr Glu Glu Thr Leu Lys Lys Leu Leu Gln Glu 
    690                 695                 700                 


Glu Val Thr Lys Val Thr Lys Phe Ile Glu Gly Gly Asp Gly His Leu 
705                 710                 715                 720 


Phe Glu Asp Glu Glu Ile Lys Arg Leu Leu Gln Gly Asp Thr Pro Val 
                725                 730                 735     


Arg Lys Leu Gln Ala Asn Lys Lys Val Gln Gly Ser Arg Arg Arg Leu 
            740                 745                 750         


Arg Glu Gly Arg Ser Gln 
        755             


<210>  2417
<211>  424
<212>  PRT
<213>  Homo Sapiens

<400>  2417

Gln Thr Pro Asn Tyr Thr Arg Pro Val Phe Leu Cys Gly Gly Asp Val 
1               5                   10                  15      


Lys Gly Glu Ser Gly Tyr Val Ala Ser Glu Gly Phe Pro Asn Leu Tyr 
            20                  25                  30          


Pro Pro Asn Lys Glu Cys Ile Trp Thr Ile Thr Val Pro Glu Gly Gln 
        35                  40                  45              


Thr Val Ser Leu Ser Phe Arg Val Phe Asp Leu Glu Leu His Pro Ala 
    50                  55                  60                  


Cys Arg Tyr Asp Ala Leu Glu Val Phe Ala Gly Ser Gly Thr Ser Gly 
65                  70                  75                  80  


Gln Arg Leu Gly Arg Phe Cys Gly Thr Phe Arg Pro Ala Pro Leu Val 
                85                  90                  95      


Ala Pro Gly Asn Gln Val Thr Leu Arg Met Thr Thr Asp Glu Gly Thr 
            100                 105                 110         


Gly Gly Arg Gly Phe Leu Leu Trp Tyr Ser Gly Arg Ala Thr Ser Gly 
        115                 120                 125             


Thr Glu His Gln Phe Cys Gly Gly Arg Leu Glu Lys Ala Gln Gly Thr 
    130                 135                 140                 


Leu Thr Thr Pro Asn Trp Pro Glu Ser Asp Tyr Pro Pro Gly Ile Ser 
145                 150                 155                 160 


Cys Ser Trp His Ile Ile Ala Pro Pro Asp Gln Val Ile Ala Leu Thr 
                165                 170                 175     


Phe Glu Lys Phe Asp Leu Glu Pro Asp Thr Tyr Cys Arg Tyr Asp Ser 
            180                 185                 190         


Val Ser Val Phe Asn Gly Ala Val Ser Asp Asp Ser Arg Arg Leu Gly 
        195                 200                 205             


Lys Phe Cys Gly Asp Ala Val Pro Gly Ser Ile Ser Ser Glu Gly Asn 
    210                 215                 220                 


Glu Leu Leu Val Gln Phe Val Ser Asp Leu Ser Val Thr Ala Asp Gly 
225                 230                 235                 240 


Phe Ser Ala Ser Tyr Lys Thr Leu Pro Arg Gly Thr Ala Lys Glu Gly 
                245                 250                 255     


Gln Gly Pro Gly Pro Lys Arg Gly Thr Glu Pro Lys Val Lys Leu Pro 
            260                 265                 270         


Pro Lys Ser Gln Pro Pro Glu Lys Thr Glu Glu Ser Pro Ser Ala Pro 
        275                 280                 285             


Asp Ala Pro Thr Cys Pro Lys Gln Cys Arg Arg Thr Gly Thr Leu Gln 
    290                 295                 300                 


Ser Asn Phe Cys Ala Ser Ser Leu Val Val Thr Ala Thr Val Lys Ser 
305                 310                 315                 320 


Met Val Arg Glu Pro Gly Glu Gly Leu Ala Val Thr Val Ser Leu Ile 
                325                 330                 335     


Gly Ala Tyr Lys Thr Gly Gly Leu Asp Leu Pro Ser Pro Pro Thr Gly 
            340                 345                 350         


Ala Ser Leu Lys Phe Tyr Val Pro Cys Lys Gln Cys Pro Pro Met Lys 
        355                 360                 365             


Lys Gly Val Ser Tyr Leu Leu Met Gly Gln Val Glu Glu Asn Arg Gly 
    370                 375                 380                 


Pro Val Leu Pro Pro Glu Ser Phe Val Val Leu His Arg Pro Asn Gln 
385                 390                 395                 400 


Asp Gln Ile Leu Thr Asn Leu Ser Lys Arg Lys Cys Pro Ser Gln Pro 
                405                 410                 415     


Val Arg Ala Ala Ala Ser Gln Asp 
            420                 


<210>  2418
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  2418

Met Gly Arg Leu Val Ala Val Gly Leu Leu Gly Ile Ala Leu Ala Leu 
1               5                   10                  15      


Leu Gly Glu Arg Leu Leu Ala Leu Arg Asn Arg Leu Lys Ala Ser Arg 
            20                  25                  30          


Glu Val Glu Ser Val Asp Leu Pro His Cys His Leu Ile Lys Gly Ile 
        35                  40                  45              


Glu Ala Gly Ser Glu Asp Ile Asp Ile Leu Pro Asn Gly Leu Ala Phe 
    50                  55                  60                  


Phe Ser Val Gly Leu Lys Phe Pro Gly Leu His Ser Phe Ala Pro Asp 
65                  70                  75                  80  


Lys Pro Gly Gly Ile Leu Met Met Asp Leu Lys Glu Glu Lys Pro Arg 
                85                  90                  95      


Ala Arg Glu Leu Arg Ile Ser Arg Gly Phe Asp Leu Ala Ser Phe Asn 
            100                 105                 110         


Pro His Gly Ile Ser Thr Phe Ile Asp Asn Asp Asp Thr Val Tyr Leu 
        115                 120                 125             


Phe Val Val Asn His Pro Glu Phe Lys Asn Thr Val Glu Ile Phe Lys 
    130                 135                 140                 


Phe Glu Glu Ala Glu Asn Ser Leu Leu His Leu Lys Thr Val Lys His 
145                 150                 155                 160 


Glu Leu Leu Pro Ser Val Asn Asp Ile Thr Ala Val Gly Pro Ala His 
                165                 170                 175     


Phe Tyr Ala Thr Asn Asp His Tyr Phe Ser Asp Pro Phe Leu Lys Tyr 
            180                 185                 190         


Leu Glu Thr Tyr Leu Asn Leu His Trp Ala Asn Val Val Tyr Tyr Ser 
        195                 200                 205             


Pro Asn Glu Val Lys Val Val Ala Glu Gly Phe Asp Ser Ala Asn Gly 
    210                 215                 220                 


Ile Asn Ile Ser Pro Asp Asp Lys Tyr Ile Tyr Val Ala Asp Ile Leu 
225                 230                 235                 240 


Ala His Glu Ile His Val Leu Glu Lys His Thr Asn Met Asn Leu Thr 
                245                 250                 255     


Gln Leu Lys Val Leu Glu Leu Asp Thr Leu Val Asp Asn Leu Ser Ile 
            260                 265                 270         


Asp Pro Ser Ser Gly Asp Ile Trp Val Gly Cys His Pro Asn Gly Gln 
        275                 280                 285             


Lys Leu Phe Val Tyr Asp Pro Asn Asn Pro Pro Ser Ser Glu Val Leu 
    290                 295                 300                 


Arg Ile Gln Asn Ile Leu Ser Glu Lys Pro Thr Val Thr Thr Val Tyr 
305                 310                 315                 320 


Ala Asn Asn Gly Ser Val Leu Gln Gly Ser Ser Val Ala Ser Val Tyr 
                325                 330                 335     


Asp Gly Lys Leu Leu Ile Gly Thr Leu Tyr His Arg Ala Leu Tyr Cys 
            340                 345                 350         


Glu Leu 
        


<210>  2419
<211>  354
<212>  PRT
<213>  Homo Sapiens

<400>  2419

Met Gly Lys Leu Val Ala Leu Val Leu Leu Gly Val Gly Leu Ser Leu 
1               5                   10                  15      


Val Gly Glu Met Phe Leu Ala Phe Arg Glu Arg Val Asn Ala Ser Arg 
            20                  25                  30          


Glu Val Glu Pro Val Glu Pro Glu Asn Cys His Leu Ile Glu Glu Leu 
        35                  40                  45              


Glu Asn Gly Ser Glu Asp Ile Asp Ile Leu Pro Ser Gly Leu Ala Phe 
    50                  55                  60                  


Ile Ser Ser Gly Leu Lys Tyr Pro Gly Met Pro Asn Phe Ala Pro Asp 
65                  70                  75                  80  


Glu Pro Gly Lys Ile Phe Leu Met Asp Leu Asn Glu Gln Asn Pro Arg 
                85                  90                  95      


Ala Gln Ala Leu Glu Ile Ser Gly Gly Phe Asp Lys Glu Leu Phe Asn 
            100                 105                 110         


Pro His Gly Ile Ser Ile Phe Ile Asp Lys Asp Asn Thr Val Tyr Leu 
        115                 120                 125             


Tyr Val Val Asn His Pro His Met Lys Ser Thr Val Glu Ile Phe Lys 
    130                 135                 140                 


Phe Glu Glu Gln Gln Arg Ser Leu Val Tyr Leu Lys Thr Ile Lys His 
145                 150                 155                 160 


Glu Leu Leu Lys Ser Val Asn Asp Ile Val Val Leu Gly Pro Glu Gln 
                165                 170                 175     


Phe Tyr Ala Thr Arg Asp His Tyr Phe Thr Asn Ser Leu Leu Ser Phe 
            180                 185                 190         


Phe Glu Met Ile Leu Asp Leu Arg Trp Thr Tyr Val Leu Phe Tyr Ser 
        195                 200                 205             


Pro Arg Glu Val Lys Val Val Ala Lys Gly Phe Cys Ser Ala Asn Gly 
    210                 215                 220                 


Ile Thr Val Ser Ala Asp Gln Lys Tyr Val Tyr Val Ala Asp Val Ala 
225                 230                 235                 240 


Ala Lys Asn Ile His Ile Met Glu Lys His Asp Asn Trp Asp Leu Thr 
                245                 250                 255     


Gln Leu Lys Val Ile Gln Leu Gly Thr Leu Val Asp Asn Leu Thr Val 
            260                 265                 270         


Asp Pro Ala Thr Gly Asp Ile Leu Ala Gly Cys His Pro Asn Pro Met 
        275                 280                 285             


Lys Leu Leu Asn Tyr Asn Pro Glu Asp Pro Pro Gly Ser Glu Val Leu 
    290                 295                 300                 


Arg Ile Gln Asn Val Leu Ser Glu Lys Pro Arg Val Ser Thr Val Tyr 
305                 310                 315                 320 


Ala Asn Asn Gly Ser Val Leu Gln Gly Thr Ser Val Ala Ser Val Tyr 
                325                 330                 335     


His Gly Lys Ile Leu Ile Gly Thr Val Phe His Lys Thr Leu Tyr Cys 
            340                 345                 350         


Glu Leu 
        


<210>  2420
<211>  302
<212>  PRT
<213>  Homo Sapiens

<400>  2420

Lys Pro Thr Val Arg Lys Glu Arg Val Val Arg Pro Asp Ser Glu Leu 
1               5                   10                  15      


Gly Glu Arg Pro Pro Glu Asp Asn Gln Ser Phe Gln Tyr Asp His Glu 
            20                  25                  30          


Ala Phe Leu Gly Lys Glu Asp Ser Lys Thr Phe Asp Gln Leu Thr Pro 
        35                  40                  45              


Asp Glu Ser Lys Glu Arg Leu Gly Lys Ile Val Asp Arg Ile Asp Asn 
    50                  55                  60                  


Asp Gly Asp Gly Phe Val Thr Thr Glu Glu Leu Lys Thr Trp Ile Lys 
65                  70                  75                  80  


Arg Val Gln Lys Arg Tyr Ile Phe Asp Asn Val Ala Lys Val Trp Lys 
                85                  90                  95      


Asp Tyr Asp Arg Asp Lys Asp Asp Lys Ile Ser Trp Glu Glu Tyr Lys 
            100                 105                 110         


Gln Ala Thr Tyr Gly Tyr Tyr Leu Gly Asn Pro Ala Glu Phe His Asp 
        115                 120                 125             


Ser Ser Asp His His Thr Phe Lys Lys Met Leu Pro Arg Asp Glu Arg 
    130                 135                 140                 


Arg Phe Lys Ala Ala Asp Leu Asn Gly Asp Leu Thr Ala Thr Arg Glu 
145                 150                 155                 160 


Glu Phe Thr Ala Phe Leu His Pro Glu Glu Phe Glu His Met Lys Glu 
                165                 170                 175     


Ile Val Val Leu Glu Thr Leu Glu Asp Ile Asp Lys Asn Gly Asp Gly 
            180                 185                 190         


Phe Val Asp Gln Asp Glu Tyr Ile Ala Asp Met Phe Ser His Glu Glu 
        195                 200                 205             


Asn Gly Pro Glu Pro Asp Trp Val Leu Ser Glu Arg Glu Gln Phe Asn 
    210                 215                 220                 


Glu Phe Arg Asp Leu Asn Lys Asp Gly Lys Leu Asp Lys Asp Glu Ile 
225                 230                 235                 240 


Arg His Trp Ile Leu Pro Gln Asp Tyr Asp His Ala Gln Ala Glu Ala 
                245                 250                 255     


Arg His Leu Val Tyr Glu Ser Asp Lys Asn Lys Asp Glu Lys Leu Thr 
            260                 265                 270         


Lys Glu Glu Ile Leu Glu Asn Trp Asn Met Phe Val Gly Ser Gln Ala 
        275                 280                 285             


Thr Asn Tyr Gly Glu Asp Leu Thr Lys Asn His Asp Glu Leu 
    290                 295                 300         


<210>  2421
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  2421

Cys Gly Pro Gly Arg Gly Phe Gly Lys Arg Arg His Pro Lys Lys Leu 
1               5                   10                  15      


Thr Pro Leu Ala Tyr Lys Gln Phe Ile Pro Asn Val Ala Glu Lys Thr 
            20                  25                  30          


Leu Gly Ala Ser Gly Arg Tyr Glu Gly Lys Ile Ser Arg Asn Ser Glu 
        35                  40                  45              


Arg Phe Lys Glu Leu Thr Pro Asn Tyr Asn Pro Asp Ile Ile Phe Lys 
    50                  55                  60                  


Asp Glu Glu Asn Thr Gly Ala Asp Arg Leu Met Thr Gln Arg Cys Lys 
65                  70                  75                  80  


Asp Lys Leu Asn Ala Leu Ala Ile Ser Val Met Asn Gln Trp Pro Gly 
                85                  90                  95      


Val Lys Leu Arg Val Thr Glu Gly Trp Asp Glu Asp Gly His His Ser 
            100                 105                 110         


Glu Glu Ser Leu His Tyr Glu Gly Arg Ala Val Asp Ile Thr Thr Ser 
        115                 120                 125             


Asp Arg Asp Arg Ser Lys Tyr Gly Met Leu Ala Arg Leu Ala Val Glu 
    130                 135                 140                 


Ala Gly Phe Asp Trp Val Tyr Tyr Glu Ser Lys Ala His Ile His Cys 
145                 150                 155                 160 


Ser Val Lys Ala Glu Asn Ser Val Ala Ala Lys Ser Gly Gly Cys Phe 
                165                 170                 175     


Pro Gly Ser Ala Thr Val His Leu Glu Gln Gly Gly Thr Lys Leu Val 
            180                 185                 190         


Lys Asp Leu Ser Pro Gly Asp Arg Val Leu Ala Ala Asp Asp Gln Gly 
        195                 200                 205             


Arg Leu Leu Tyr Ser Asp Phe Leu Thr Phe Leu Asp Arg Asp Asp Gly 
    210                 215                 220                 


Ala Lys Lys Val Phe Tyr Val Ile Glu Thr Arg Glu Pro Arg Glu Arg 
225                 230                 235                 240 


Leu Leu Leu Thr Ala Ala His Leu Leu Phe Val Ala Pro His Asn Asp 
                245                 250                 255     


Ser Ala Thr Gly Glu Pro Glu Ala Ser Ser Gly Ser Gly Pro Pro Ser 
            260                 265                 270         


Gly Gly Ala Leu Gly Pro Arg Ala Leu Phe Ala Ser Arg Val Arg Pro 
        275                 280                 285             


Gly Gln Arg Val Tyr Val Val Ala Glu Arg Asp Gly Asp Arg Arg Leu 
    290                 295                 300                 


Leu Pro Ala Ala Val His Ser Val Thr Leu Ser Glu Glu Ala Ala Gly 
305                 310                 315                 320 


Ala Tyr Ala Pro Leu Thr Ala Gln Gly Thr Ile Leu Ile Asn Arg Val 
                325                 330                 335     


Leu Ala Ser Cys Tyr Ala Val Ile Glu Glu His Ser Trp Ala His Arg 
            340                 345                 350         


Ala Phe Ala Pro Phe Arg Leu Ala His Ala Leu Leu Ala Ala Leu Ala 
        355                 360                 365             


Pro Ala Arg Thr Asp Arg Gly Gly Asp Ser Gly Gly Gly Asp Arg Gly 
    370                 375                 380                 


Gly Gly Gly Gly Arg Val Ala Leu Thr Ala Pro Gly Ala Ala Asp Ala 
385                 390                 395                 400 


Pro Gly Ala Gly Ala Thr Ala Gly Ile His Trp Tyr Ser Gln Leu Leu 
                405                 410                 415     


Tyr Gln Ile Gly Thr Trp Leu Leu Asp Ser Glu Ala Leu His Pro Leu 
            420                 425                 430         


Gly Met Ala Val Lys Ser Ser 
        435                 


<210>  2422
<211>  496
<212>  PRT
<213>  Homo Sapiens

<400>  2422

Lys Ser Ile Gly Thr Phe Ser Asp Pro Cys Lys Asp Pro Thr Arg Ile 
1               5                   10                  15      


Thr Ser Pro Asn Asp Pro Cys Leu Thr Gly Lys Gly Asp Ser Ser Gly 
            20                  25                  30          


Phe Ser Ser Tyr Ser Gly Ser Ser Ser Ser Gly Ser Ser Ile Ser Ser 
        35                  40                  45              


Ala Arg Ser Ser Gly Gly Gly Ser Ser Gly Ser Ser Ser Gly Ser Ser 
    50                  55                  60                  


Ile Ala Gln Gly Gly Ser Ala Gly Ser Phe Lys Pro Gly Thr Gly Tyr 
65                  70                  75                  80  


Ser Gln Val Ser Tyr Ser Ser Gly Ser Gly Ser Ser Leu Gln Gly Ala 
                85                  90                  95      


Ser Gly Ser Ser Gln Leu Gly Ser Ser Ser Ser His Ser Gly Ser Ser 
            100                 105                 110         


Gly Ser His Ser Gly Ser Ser Ser His Ser Ser Ser Ser Ser Ser Phe 
        115                 120                 125             


Gln Phe Ser Ser Ser Ser Phe Gln Val Gly Asn Gly Ser Ala Leu Pro 
    130                 135                 140                 


Thr Asn Asp Asn Ser Tyr Arg Gly Ile Leu Asn Pro Ser Gln Pro Gly 
145                 150                 155                 160 


Gln Ser Ser Ser Ser Ser Gln Thr Phe Gly Val Ser Ser Ser Gly Gln 
                165                 170                 175     


Ser Val Ser Ser Asn Gln Arg Pro Cys Ser Ser Asp Ile Pro Asp Ser 
            180                 185                 190         


Pro Cys Ser Gly Gly Pro Ile Val Ser His Ser Gly Pro Tyr Ile Pro 
        195                 200                 205             


Ser Ser His Ser Val Ser Gly Gly Gln Arg Pro Val Val Val Val Val 
    210                 215                 220                 


Asp Gln His Gly Ser Gly Ala Pro Gly Val Val Gln Gly Pro Pro Cys 
225                 230                 235                 240 


Ser Asn Gly Gly Leu Pro Gly Lys Pro Cys Pro Pro Ile Thr Ser Val 
                245                 250                 255     


Asp Lys Ser Tyr Gly Gly Tyr Glu Val Val Gly Gly Ser Ser Asp Ser 
            260                 265                 270         


Tyr Leu Val Pro Gly Met Thr Tyr Ser Lys Gly Lys Ile Tyr Pro Val 
        275                 280                 285             


Gly Tyr Phe Thr Lys Glu Asn Pro Val Lys Gly Ser Pro Gly Val Pro 
    290                 295                 300                 


Ser Phe Ala Ala Gly Pro Pro Ile Ser Glu Gly Lys Tyr Phe Ser Ser 
305                 310                 315                 320 


Asn Pro Ile Ile Pro Ser Gln Ser Ala Ala Ser Ser Ala Ile Ala Phe 
                325                 330                 335     


Gln Pro Val Gly Thr Gly Gly Val Gln Leu Cys Gly Gly Gly Ser Thr 
            340                 345                 350         


Gly Ser Lys Gly Pro Cys Ser Pro Ser Ser Ser Arg Val Pro Ser Ser 
        355                 360                 365             


Ser Ser Ile Ser Ser Ser Ser Gly Leu Pro Tyr His Pro Cys Gly Ser 
    370                 375                 380                 


Ala Ser Gln Ser Pro Cys Ser Pro Pro Gly Thr Gly Ser Phe Ser Ser 
385                 390                 395                 400 


Ser Ser Ser Ser Gln Ser Ser Gly Lys Ile Ile Leu Gln Pro Cys Gly 
                405                 410                 415     


Ser Lys Ser Ser Ser Ser Gly His Pro Cys Met Ser Val Ser Ser Leu 
            420                 425                 430         


Thr Leu Thr Gly Gly Pro Asp Gly Ser Pro His Pro Asp Pro Ser Ala 
        435                 440                 445             


Gly Ala Lys Pro Cys Gly Ser Ser Ser Ala Gly Lys Ile Pro Cys Arg 
    450                 455                 460                 


Ser Ile Arg Asp Ile Leu Ala Gln Val Lys Pro Leu Gly Pro Gln Leu 
465                 470                 475                 480 


Ala Asp Pro Glu Val Phe Leu Pro Gln Gly Glu Leu Leu Asp Ser Pro 
                485                 490                 495     


<210>  2423
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  2423

Glu Pro Leu Glu Lys Val Ala Ser Val Gly Asn Ser Arg Pro Thr Gly 
1               5                   10                  15      


Gln Gln Leu Glu Ser Leu Gly Leu Leu Ala Pro Gly Glu Gln Ser Leu 
            20                  25                  30          


Pro Cys Thr Glu Arg Lys Pro Ala Ala Thr Ala Arg Leu Ser Arg Arg 
        35                  40                  45              


Gly Thr Ser Leu Ser Pro Pro Pro Glu Ser Ser Gly Ser Pro Gln Gln 
    50                  55                  60                  


Pro Gly Leu Ser Ala Pro His Ser Arg Gln Ile Pro Ala Pro Gln Gly 
65                  70                  75                  80  


Ala Val Leu Val Gln Arg Glu Lys Asp Leu Pro Asn Tyr Asn Trp Asn 
                85                  90                  95      


Ser Phe Gly Leu Arg Phe Gly Lys Arg Glu Ala Ala Pro Gly Asn His 
            100                 105                 110         


Gly Arg Ser Ala Gly Arg Gly 
        115                 


<210>  2424
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  2424

Gln Pro Gly Ala Ala Ser Ala Ala Ile Asn Ala Ser Val Gly Ala Ala 
1               5                   10                  15      


Gly Ser Ala Glu Asn Ala Pro Ser Lys Glu Val Leu Asp Ser Phe Leu 
            20                  25                  30          


Asp Leu Ala Arg Asn Ile Phe Pro Ser Asn Leu Val Ser Ala Ala Phe 
        35                  40                  45              


Arg Ser Tyr Ser Thr Thr Tyr Glu Glu Arg Asn Ile Thr Gly Thr Arg 
    50                  55                  60                  


Val Lys Val Pro Val Gly Gln 
65                  70      


<210>  2425
<211>  364
<212>  PRT
<213>  Homo Sapiens

<400>  2425

Tyr Lys Leu Val Cys Tyr Phe Thr Asn Trp Ser Gln Asp Arg Gln Glu 
1               5                   10                  15      


Pro Gly Lys Phe Thr Pro Glu Asn Ile Asp Pro Phe Leu Cys Ser His 
            20                  25                  30          


Leu Ile Tyr Ser Phe Ala Ser Ile Glu Asn Asn Lys Val Ile Ile Lys 
        35                  40                  45              


Asp Lys Ser Glu Val Met Leu Tyr Gln Thr Ile Asn Ser Leu Lys Thr 
    50                  55                  60                  


Lys Asn Pro Lys Leu Lys Ile Leu Leu Ser Ile Gly Gly Tyr Leu Phe 
65                  70                  75                  80  


Gly Ser Lys Gly Phe His Pro Met Val Asp Ser Ser Thr Ser Arg Leu 
                85                  90                  95      


Glu Phe Ile Asn Ser Ile Ile Leu Phe Leu Arg Asn His Asn Phe Asp 
            100                 105                 110         


Gly Leu Asp Val Ser Trp Ile Tyr Pro Asp Gln Lys Glu Asn Thr His 
        115                 120                 125             


Phe Thr Val Leu Ile His Glu Leu Ala Glu Ala Phe Gln Lys Asp Phe 
    130                 135                 140                 


Thr Lys Ser Thr Lys Glu Arg Leu Leu Leu Thr Val Gly Val Ser Ala 
145                 150                 155                 160 


Gly Arg Gln Met Ile Asp Asn Ser Tyr Gln Val Glu Lys Leu Ala Lys 
                165                 170                 175     


Asp Leu Asp Phe Ile Asn Leu Leu Ser Phe Asp Phe His Gly Ser Trp 
            180                 185                 190         


Glu Lys Pro Leu Ile Thr Gly His Asn Ser Pro Leu Ser Lys Gly Trp 
        195                 200                 205             


Gln Asp Arg Gly Pro Ser Ser Tyr Tyr Asn Val Glu Tyr Ala Val Gly 
    210                 215                 220                 


Tyr Trp Ile His Lys Gly Met Pro Ser Glu Lys Val Val Met Gly Ile 
225                 230                 235                 240 


Pro Thr Tyr Gly His Ser Phe Thr Leu Ala Ser Ala Glu Thr Thr Val 
                245                 250                 255     


Gly Ala Pro Ala Ser Gly Pro Gly Ala Ala Gly Pro Ile Thr Glu Ser 
            260                 265                 270         


Ser Gly Phe Leu Ala Tyr Tyr Glu Ile Cys Gln Phe Leu Lys Gly Ala 
        275                 280                 285             


Lys Ile Thr Arg Leu Gln Asp Gln Gln Val Pro Tyr Ala Val Lys Gly 
    290                 295                 300                 


Asn Gln Trp Val Gly Tyr Asp Asp Val Lys Ser Met Glu Thr Lys Val 
305                 310                 315                 320 


Gln Phe Leu Lys Asn Leu Asn Leu Gly Gly Ala Met Ile Trp Ser Ile 
                325                 330                 335     


Asp Met Asp Asp Phe Thr Gly Lys Ser Cys Asn Gln Gly Pro Tyr Pro 
            340                 345                 350         


Leu Val Gln Ala Val Lys Arg Ser Leu Gly Ser Leu 
        355                 360                 


<210>  2426
<211>  410
<212>  PRT
<213>  Homo Sapiens

<400>  2426

Gln Asp Phe Gly Pro Thr Arg Phe Ile Cys Thr Ser Val Pro Val Asp 
1               5                   10                  15      


Ala Asp Met Cys Ala Ala Ser Val Ala Ala Gly Gly Ala Glu Glu Leu 
            20                  25                  30          


Arg Ser Ser Val Leu Gln Leu Arg Glu Thr Val Leu Gln Gln Lys Glu 
        35                  40                  45              


Thr Ile Leu Ser Gln Lys Glu Thr Ile Arg Glu Leu Thr Ala Lys Leu 
    50                  55                  60                  


Gly Arg Cys Glu Ser Gln Ser Thr Leu Asp Pro Gly Ala Gly Glu Ala 
65                  70                  75                  80  


Arg Ala Gly Gly Gly Arg Lys Gln Pro Gly Ser Gly Lys Asn Thr Met 
                85                  90                  95      


Gly Asp Leu Ser Arg Thr Pro Ala Ala Glu Thr Leu Ser Gln Leu Gly 
            100                 105                 110         


Gln Thr Leu Gln Ser Leu Lys Thr Arg Leu Glu Asn Leu Glu Gln Tyr 
        115                 120                 125             


Ser Arg Leu Asn Ser Ser Ser Gln Thr Asn Ser Leu Lys Asp Leu Leu 
    130                 135                 140                 


Gln Ser Lys Ile Asp Glu Leu Glu Arg Gln Val Leu Ser Arg Val Asn 
145                 150                 155                 160 


Thr Leu Glu Glu Gly Lys Gly Gly Pro Arg Asn Asp Thr Glu Glu Arg 
                165                 170                 175     


Val Lys Ile Glu Thr Ala Leu Thr Ser Leu His Gln Arg Ile Ser Glu 
            180                 185                 190         


Leu Glu Lys Gly Gln Lys Asp Asn Arg Pro Gly Asp Lys Phe Gln Leu 
        195                 200                 205             


Thr Phe Pro Leu Arg Thr Asn Tyr Met Tyr Ala Lys Val Lys Lys Ser 
    210                 215                 220                 


Leu Pro Glu Met Tyr Ala Phe Thr Val Cys Met Trp Leu Lys Ser Ser 
225                 230                 235                 240 


Ala Thr Pro Gly Val Gly Thr Pro Phe Ser Tyr Ala Val Pro Gly Gln 
                245                 250                 255     


Ala Asn Glu Leu Val Leu Ile Glu Trp Gly Asn Asn Pro Met Glu Ile 
            260                 265                 270         


Leu Ile Asn Asp Lys Val Ala Lys Leu Pro Phe Val Ile Asn Asp Gly 
        275                 280                 285             


Lys Trp His His Ile Cys Val Thr Trp Thr Thr Arg Asp Gly Val Trp 
    290                 295                 300                 


Glu Ala Tyr Gln Asp Gly Thr Gln Gly Gly Ser Gly Glu Asn Leu Ala 
305                 310                 315                 320 


Pro Tyr His Pro Ile Lys Pro Gln Gly Val Leu Val Leu Gly Gln Glu 
                325                 330                 335     


Gln Asp Thr Leu Gly Gly Gly Phe Asp Ala Thr Gln Ala Phe Val Gly 
            340                 345                 350         


Glu Leu Ala His Phe Asn Ile Trp Asp Arg Lys Leu Thr Pro Gly Glu 
        355                 360                 365             


Val Tyr Asn Leu Ala Thr Cys Ser Thr Lys Ala Leu Ser Gly Asn Val 
    370                 375                 380                 


Ile Ala Trp Ala Glu Ser His Ile Glu Ile Tyr Gly Gly Ala Thr Lys 
385                 390                 395                 400 


Trp Thr Phe Glu Ala Cys Arg Gln Ile Asn 
                405                 410 


<210>  2427
<211>  214
<212>  PRT
<213>  Homo Sapiens

<400>  2427

Lys Gly Cys Val Gly Cys Ala Thr Glu Glu Arg Leu Phe His Lys Leu 
1               5                   10                  15      


Phe Ser His Tyr Asn Gln Phe Ile Arg Pro Val Glu Asn Val Ser Asp 
            20                  25                  30          


Pro Val Thr Val His Phe Glu Val Ala Ile Thr Gln Leu Ala Asn Val 
        35                  40                  45              


Asp Glu Val Asn Gln Ile Met Glu Thr Asn Leu Trp Leu Arg His Ile 
    50                  55                  60                  


Trp Asn Asp Tyr Lys Leu Arg Trp Asp Pro Met Glu Tyr Asp Gly Ile 
65                  70                  75                  80  


Glu Thr Leu Arg Val Pro Ala Asp Lys Ile Trp Lys Pro Asp Ile Val 
                85                  90                  95      


Leu Tyr Asn Asn Ala Val Gly Asp Phe Gln Val Glu Gly Lys Thr Lys 
            100                 105                 110         


Ala Leu Leu Lys Tyr Asn Gly Met Ile Thr Trp Thr Pro Pro Ala Ile 
        115                 120                 125             


Phe Lys Ser Ser Cys Pro Met Asp Ile Thr Phe Phe Pro Phe Asp His 
    130                 135                 140                 


Gln Asn Cys Ser Leu Lys Phe Gly Ser Trp Thr Tyr Asp Lys Ala Glu 
145                 150                 155                 160 


Ile Asp Leu Leu Ile Ile Gly Ser Lys Val Asp Met Asn Asp Phe Trp 
                165                 170                 175     


Glu Asn Ser Glu Trp Glu Ile Ile Asp Ala Ser Gly Tyr Lys His Asp 
            180                 185                 190         


Ile Lys Tyr Asn Cys Cys Glu Glu Ile Tyr Thr Asp Ile Thr Tyr Ser 
        195                 200                 205             


Phe Tyr Ile Arg Arg Leu 
    210                 


<210>  2428
<211>  121
<212>  PRT
<213>  Homo Sapiens

<400>  2428

Arg Pro Gln Glu Arg Met Val Gly Glu Leu Arg Asp Leu Ser Pro Asp 
1               5                   10                  15      


Asp Pro Gln Val Gln Lys Ala Ala Gln Ala Ala Val Ala Ser Tyr Asn 
            20                  25                  30          


Met Gly Ser Asn Ser Ile Tyr Tyr Phe Arg Asp Thr His Ile Ile Lys 
        35                  40                  45              


Ala Gln Ser Gln Leu Val Ala Gly Ile Lys Tyr Phe Leu Thr Met Glu 
    50                  55                  60                  


Met Gly Ser Thr Asp Cys Arg Lys Thr Arg Val Thr Gly Asp His Val 
65                  70                  75                  80  


Asp Leu Thr Thr Cys Pro Leu Ala Ala Gly Ala Gln Gln Glu Lys Leu 
                85                  90                  95      


Arg Cys Asp Phe Glu Val Leu Val Val Pro Trp Gln Asn Ser Ser Gln 
            100                 105                 110         


Leu Leu Lys His Asn Cys Val Gln Met 
        115                 120     


<210>  2429
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  2429

Glu Thr Thr Thr Gln Gly Pro Gly Val Leu Leu Pro Leu Pro Lys Gly 
1               5                   10                  15      


Ala Cys Thr Gly Trp Met Ala Gly Ile Pro Gly His Pro Gly His Asn 
            20                  25                  30          


Gly Ala Pro Gly Arg Asp Gly Arg Asp Gly Thr Pro Gly Glu Lys Gly 
        35                  40                  45              


Glu Lys Gly Asp Pro Gly Leu Ile Gly Pro Lys Gly Asp Ile Gly Glu 
    50                  55                  60                  


Thr Gly Val Pro Gly Ala Glu Gly Pro Arg Gly Phe Pro Gly Ile Gln 
65                  70                  75                  80  


Gly Arg Lys Gly Glu Pro Gly Glu Gly Ala Tyr Val Tyr Arg Ser Ala 
                85                  90                  95      


Phe Ser Val Gly Leu Glu Thr Tyr Val Thr Ile Pro Asn Met Pro Ile 
            100                 105                 110         


Arg Phe Thr Lys Ile Phe Tyr Asn Gln Gln Asn His Tyr Asp Gly Ser 
        115                 120                 125             


Thr Gly Lys Phe His Cys Asn Ile Pro Gly Leu Tyr Tyr Phe Ala Tyr 
    130                 135                 140                 


His Ile Thr Val Tyr Met Lys Asp Val Lys Val Ser Leu Phe Lys Lys 
145                 150                 155                 160 


Asp Lys Ala Met Leu Phe Thr Tyr Asp Gln Tyr Gln Glu Asn Asn Val 
                165                 170                 175     


Asp Gln Ala Ser Gly Ser Val Leu Leu His Leu Glu Val Gly Asp Gln 
            180                 185                 190         


Val Trp Leu Gln Val Tyr Gly Glu Gly Glu Arg Asn Gly Leu Tyr Ala 
        195                 200                 205             


Asp Asn Asp Asn Asp Ser Thr Phe Thr Gly Phe Leu Leu Tyr His Asp 
    210                 215                 220                 


Thr Asn 
225     


<210>  2430
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  2430

Ala Gln Phe Val Ser Ser Val Pro Arg Cys Asp Leu Val Asp Leu Gly 
1               5                   10                  15      


Glu Gly Lys Ile Cys Phe Cys Cys Glu Glu Phe Gln Pro Ala Lys Cys 
            20                  25                  30          


Thr Asp Lys Glu Asn Ala Leu Lys Leu Phe Pro Val Gln Pro Cys Ser 
        35                  40                  45              


Ala Val His Leu Leu Leu Lys Lys 
    50                  55      


<210>  2431
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2431

Glu Gln Gln Val Pro Leu Val Leu Trp Ser Ser Asp Arg Asp Leu Trp 
1               5                   10                  15      


Ala Pro Ala Ala Asp Thr His Glu Gly His Ile Thr Ser Asp Leu Gln 
            20                  25                  30          


Leu Ser Thr Tyr Leu Asp Pro Ala Leu Glu Leu Gly Pro Arg Asn Val 
        35                  40                  45              


Leu Leu Phe Leu Gln Asp Lys Leu Ser Ile Glu Asp Phe Thr Ala Tyr 
    50                  55                  60                  


Gly Gly Val Phe Gly Asn Lys Gln Asp Ser Ala Phe Ser Asn Leu Glu 
65                  70                  75                  80  


Asn Ala Leu Asp Leu Ala Pro Ser Ser Leu Val Leu Pro Ala Val Asp 
                85                  90                  95      


Trp Tyr Ala Val Ser Thr Leu Thr Thr Tyr Leu Gln Glu Lys Leu Gly 
            100                 105                 110         


Ala Ser Pro Leu His Val Asp Leu Ala Thr Leu Arg Glu Leu Lys Leu 
        115                 120                 125             


Asn Ala Ser Leu Pro Ala Leu Leu Leu Ile Arg Leu Pro Tyr Thr Ala 
    130                 135                 140                 


Ser Ser Gly Leu Met Ala Pro Arg Glu Val Leu Thr Gly Asn Asp Glu 
145                 150                 155                 160 


Val Ile Gly Gln Val Leu Ser Thr Leu Lys Ser Glu Asp Val Pro Tyr 
                165                 170                 175     


Thr Ala Ala Leu Thr Ala Val Arg Pro Ser Arg Val Ala Arg Asp Val 
            180                 185                 190         


Ala Val Val Ala Gly Gly Leu Gly Arg Gln Leu Leu Gln Lys Gln Pro 
        195                 200                 205             


Val Ser Pro Val Ile His Pro Pro Val Ser Tyr Asn Asp Thr Ala Pro 
    210                 215                 220                 


Arg Ile Leu Phe Trp Ala Gln Asn Phe Ser Val Ala Tyr Lys Asp Gln 
225                 230                 235                 240 


Trp Glu Asp Leu Thr Pro Leu Thr Phe Gly Val Gln Glu Leu Asn Leu 
                245                 250                 255     


Thr Gly Ser Phe Trp Asn Asp Ser Phe Ala Arg Leu Ser Leu Thr Tyr 
            260                 265                 270         


Glu Arg Leu Phe Gly Thr Thr Val Thr Phe Lys Phe Ile Leu Ala Asn 
        275                 280                 285             


Arg Leu Tyr Pro Val Ser Ala Arg His Trp Phe Thr Met Glu Arg Leu 
    290                 295                 300                 


Glu Val His Ser Asn Gly Ser Val Ala Tyr Phe Asn Ala Ser Gln Val 
305                 310                 315                 320 


Thr Gly Pro Ser Ile Tyr Ser Phe His Cys Glu Tyr Val Ser Ser Leu 
                325                 330                 335     


Ser Lys Lys Gly Ser Leu Leu Val Ala Arg Thr Gln Pro Ser Pro Trp 
            340                 345                 350         


Gln Met Met Leu Gln Asp Phe Gln Ile Gln Ala Phe Asn Val Met Gly 
        355                 360                 365             


Glu Gln Phe Ser Tyr Ala Ser Asp Cys Ala 
    370                 375             


<210>  2432
<211>  82
<212>  PRT
<213>  Homo Sapiens

<400>  2432

Gly Ser Met Ile Ser Asn Met Asn Ala Ser Arg Ala Glu Phe Gln Ala 
1               5                   10                  15      


Lys Ile Asp Ser Ile Lys Gln Tyr Met Gln Phe Arg Lys Val Thr Lys 
            20                  25                  30          


Asp Leu Glu Thr Arg Val Ile Arg Trp Phe Asp Tyr Leu Trp Ala Asn 
        35                  40                  45              


Lys Lys Thr Val Asp Glu Lys Glu Val Leu Lys Ser Leu Pro Asp Lys 
    50                  55                  60                  


Leu Lys Ala Glu Ile Ala Ile Asn Val His Leu Asp Thr Leu Lys Lys 
65                  70                  75                  80  


Val Arg 
        


<210>  2433
<211>  118
<212>  PRT
<213>  Homo Sapiens

<400>  2433

Gln Ser Thr Asp Asn Asp Val Asn Tyr Glu Asp Phe Thr Phe Thr Ile 
1               5                   10                  15      


Pro Asp Val Glu Asp Ser Ser Gln Arg Pro Asp Gln Gly Pro Gln Arg 
            20                  25                  30          


Pro Pro Pro Glu Gly Leu Leu Pro Arg Pro Pro Gly Asp Ser Gly Asn 
        35                  40                  45              


Gln Asp Asp Gly Pro Gln Gln Arg Pro Pro Lys Pro Gly Gly His His 
    50                  55                  60                  


Arg His Pro Pro Pro Pro Pro Phe Gln Asn Gln Gln Arg Pro Pro Gln 
65                  70                  75                  80  


Arg Gly His Arg Gln Leu Ser Leu Pro Arg Phe Pro Ser Val Ser Leu 
                85                  90                  95      


Gln Glu Ala Ser Ser Phe Phe Arg Arg Asp Arg Pro Ala Arg His Pro 
            100                 105                 110         


Gln Glu Gln Pro Leu Trp 
        115             


<210>  2434
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2434

Lys Leu Glu Val Glu Gly Asn Phe Tyr Ser Glu Asn Val Ser Arg Ile 
1               5                   10                  15      


Leu Asp Asn Leu Leu Glu Gly Tyr Asp Asn Arg Leu Arg Pro Gly Phe 
            20                  25                  30          


Gly Gly Ala Val Thr Glu Val Lys Thr Asp Ile Tyr Val Thr Ser Phe 
        35                  40                  45              


Gly Pro Val Ser Asp Val Glu Met Glu Tyr Thr Met Asp Val Phe Phe 
    50                  55                  60                  


Arg Gln Thr Trp Thr Asp Glu Arg Leu Lys Phe Gly Gly Pro Thr Glu 
65                  70                  75                  80  


Ile Leu Ser Leu Asn Asn Leu Met Val Ser Lys Ile Trp Thr Pro Asp 
                85                  90                  95      


Thr Phe Phe Arg Asn Gly Lys Lys Ser Ile Ala His Asn Met Thr Thr 
            100                 105                 110         


Pro Asn Lys Leu Phe Arg Ile Met Gln Asn Gly Thr Ile Leu Tyr Thr 
        115                 120                 125             


Met Arg Leu Thr Ile Asn Ala Asp Cys Pro Met Arg Leu Val Asn Phe 
    130                 135                 140                 


Pro Met Asp Gly His Ala Cys Pro Leu Lys Phe Gly Ser Tyr Ala Tyr 
145                 150                 155                 160 


Pro Lys Ser Glu Ile Ile Tyr Thr Trp Lys Lys Gly Pro Leu Tyr Ser 
                165                 170                 175     


Val Glu Val Pro Glu Glu Ser Ser Ser Leu Leu Gln Tyr Asp Leu Ile 
            180                 185                 190         


Gly Gln Thr Val Ser Ser Glu Thr Ile Lys Ser Asn Thr Gly Glu Tyr 
        195                 200                 205             


Val Ile Met Thr Val Tyr Phe His Leu Gln Arg Lys Met Gly Tyr 
    210                 215                 220             


<210>  2435
<211>  526
<212>  PRT
<213>  Homo Sapiens

<400>  2435

Ser Val His Phe Asn Asp Pro Lys Tyr Pro Gln Gln Trp His Leu Asn 
1               5                   10                  15      


Asn Arg Arg Ser Pro Gly Arg Asp Ile Asn Val Thr Gly Val Trp Glu 
            20                  25                  30          


Arg Asn Val Thr Gly Arg Gly Val Thr Val Val Val Val Asp Asp Gly 
        35                  40                  45              


Val Glu His Thr Ile Gln Asp Ile Ala Pro Asn Tyr Ser Pro Glu Gly 
    50                  55                  60                  


Ser Tyr Asp Leu Asn Ser Asn Asp Pro Asp Pro Met Pro His Pro Asp 
65                  70                  75                  80  


Val Glu Asn Gly Asn His His Gly Thr Arg Cys Ala Gly Glu Ile Ala 
                85                  90                  95      


Ala Val Pro Asn Asn Ser Phe Cys Ala Val Gly Val Ala Tyr Gly Ser 
            100                 105                 110         


Arg Ile Ala Gly Ile Arg Val Leu Asp Gly Pro Leu Thr Asp Ser Met 
        115                 120                 125             


Glu Ala Val Ala Phe Asn Lys His Tyr Gln Ile Asn Asp Ile Tyr Ser 
    130                 135                 140                 


Cys Ser Trp Gly Pro Asp Asp Asp Gly Lys Thr Val Asp Gly Pro His 
145                 150                 155                 160 


Gln Leu Gly Lys Ala Ala Leu Gln His Gly Val Ile Ala Gly Arg Gln 
                165                 170                 175     


Gly Phe Gly Ser Ile Phe Val Val Ala Ser Gly Asn Gly Gly Gln His 
            180                 185                 190         


Asn Asp Asn Cys Asn Tyr Asp Gly Tyr Ala Asn Ser Ile Tyr Thr Val 
        195                 200                 205             


Thr Ile Gly Ala Val Asp Glu Glu Gly Arg Met Pro Phe Tyr Ala Glu 
    210                 215                 220                 


Glu Cys Ala Ser Met Leu Ala Val Thr Phe Ser Gly Gly Asp Lys Met 
225                 230                 235                 240 


Leu Arg Ser Ile Val Thr Thr Asp Trp Asp Leu Gln Lys Gly Thr Gly 
                245                 250                 255     


Cys Thr Glu Gly His Thr Gly Thr Ser Ala Ala Ala Pro Leu Ala Ala 
            260                 265                 270         


Gly Met Ile Ala Leu Met Leu Gln Val Arg Pro Cys Leu Thr Trp Arg 
        275                 280                 285             


Asp Val Gln His Ile Ile Val Phe Thr Ala Thr Arg Tyr Glu Asp Arg 
    290                 295                 300                 


Arg Ala Glu Trp Val Thr Asn Glu Ala Gly Phe Ser His Ser His Gln 
305                 310                 315                 320 


His Gly Phe Gly Leu Leu Asn Ala Trp Arg Leu Val Asn Ala Ala Lys 
                325                 330                 335     


Ile Trp Thr Ser Val Pro Tyr Leu Ala Ser Tyr Val Ser Pro Val Leu 
            340                 345                 350         


Lys Glu Asn Lys Ala Ile Pro Gln Ser Pro Arg Ser Leu Glu Val Leu 
        355                 360                 365             


Trp Asn Val Ser Arg Met Asp Leu Glu Met Ser Gly Leu Lys Thr Leu 
    370                 375                 380                 


Glu His Val Ala Val Thr Val Ser Ile Thr His Pro Arg Arg Gly Ser 
385                 390                 395                 400 


Leu Glu Leu Lys Leu Phe Cys Pro Ser Gly Met Met Ser Leu Ile Gly 
                405                 410                 415     


Ala Pro Arg Ser Met Asp Ser Asp Pro Asn Gly Phe Asn Asp Trp Thr 
            420                 425                 430         


Phe Ser Thr Val Arg Cys Trp Gly Glu Arg Ala Arg Gly Thr Tyr Arg 
        435                 440                 445             


Leu Val Ile Arg Asp Val Gly Asp Glu Ser Phe Gln Val Gly Ile Leu 
    450                 455                 460                 


Arg Gln Trp Gln Leu Thr Leu Tyr Gly Ser Val Trp Ser Ala Val Asp 
465                 470                 475                 480 


Ile Arg Asp Arg Gln Arg Leu Leu Glu Ser Ala Met Ser Gly Lys Tyr 
                485                 490                 495     


Leu His Asp Asp Phe Ala Leu Pro Cys Pro Pro Gly Leu Lys Ile Pro 
            500                 505                 510         


Glu Glu Asp Gly Tyr Thr Ile Thr Pro Asn Thr Leu Lys Thr 
        515                 520                 525     


<210>  2436
<211>  48
<212>  PRT
<213>  Homo Sapiens

<400>  2436

Val Pro Ile Tyr Glu Lys Lys Tyr Gly Gln Val Pro Met Cys Asp Ala 
1               5                   10                  15      


Gly Glu Gln Cys Ala Val Arg Lys Gly Ala Arg Ile Gly Lys Leu Cys 
            20                  25                  30          


Asp Cys Pro Arg Gly Thr Ser Cys Asn Ser Phe Leu Leu Lys Cys Leu 
        35                  40                  45              


<210>  2437
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  2437

Met Gly Asn Cys Leu His Arg Ala Glu Leu Ser Pro Ser Thr Glu Asn 
1               5                   10                  15      


Ser Ser Gln Leu Asp Phe Glu Asp Val Trp Asn Ser Ser Tyr Gly Val 
            20                  25                  30          


Asn Asp Ser Phe Pro Asp Gly Asp Tyr Gly Ala Asn Leu Glu Ala Ala 
        35                  40                  45              


Ala Pro Cys His Ser Cys Asn Leu Leu Asp Asp Ser Ala Leu Pro 
    50                  55                  60              


<210>  2438
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  2438

Trp Ala Val Ile Arg Ile Gly Pro Asn Gly Cys Asp Ser Met Glu Phe 
1               5                   10                  15      


His Glu Ser Gly Leu Leu Arg Phe Lys Gln Val Ser Asp Met Gly Val 
            20                  25                  30          


Ile His Pro Leu Tyr Lys Ser Thr Val Gly Gly Arg Arg Asn Glu Asn 
        35                  40                  45              


Leu Val Ile Thr Gly Asn Asn Gln Pro Ile Val Phe Gln Gln Gly Thr 
    50                  55                  60                  


Thr Lys Leu Ser Val Glu Asn Asn Lys Thr Ser Ile Thr Ser Asp Ile 
65                  70                  75                  80  


Gly Met Gln Phe Phe Asp Pro Arg Thr Gln Asn Ile Leu Phe Ser Thr 
                85                  90                  95      


Asp Tyr Glu Thr His Glu Phe His Leu Pro Ser Gly Val Lys Ser Leu 
            100                 105                 110         


Asn Val Gln Lys Ala Ser Thr Glu Arg Ile Thr Ser Asn Ala Thr Ser 
        115                 120                 125             


Asp Leu Asn Ile Lys Val Asp Gly Arg Ala Ile Val Arg Gly Asn Glu 
    130                 135                 140                 


Gly Val Phe Ile Met Gly Lys Thr Ile Glu Phe His Met Gly Gly Asn 
145                 150                 155                 160 


Met Glu Leu Lys Ala Glu Asn Ser Ile Ile Leu Asn Gly Ser Val Met 
                165                 170                 175     


Val Ser Thr Thr Arg Leu Pro Ser Ser Ser Ser Gly Asp Gln Leu Gly 
            180                 185                 190         


Ser Gly Asp Trp Val Arg Tyr Lys Leu Cys Met Cys Ala Asp Gly Thr 
        195                 200                 205             


Leu Phe Lys Val Gln Val Thr Ser Gln Asn Met Gly Cys Gln Ile Ser 
    210                 215                 220                 


Asp Asn Pro Cys Gly Asn Thr His 
225                 230         


<210>  2439
<211>  267
<212>  PRT
<213>  Homo Sapiens

<400>  2439

Gln Gln Thr Thr Leu His Pro Leu Val Gly Arg Val Phe Val His Thr 
1               5                   10                  15      


Leu Asp His Glu Thr Phe Leu Ser Leu Pro Glu His Val Ala Val Pro 
            20                  25                  30          


Pro Ala Val His Ile Thr Tyr His Ala His Leu Gln Gly His Pro Asp 
        35                  40                  45              


Leu Pro Arg Trp Leu Arg Tyr Thr Gln Arg Ser Pro His His Pro Gly 
    50                  55                  60                  


Phe Leu Tyr Gly Ser Ala Thr Pro Glu Asp Arg Gly Leu Gln Val Ile 
65                  70                  75                  80  


Glu Val Thr Ala Tyr Asn Arg Asp Ser Phe Asp Thr Thr Arg Gln Arg 
                85                  90                  95      


Leu Val Leu Glu Ile Gly Asp Pro Glu Gly Pro Leu Leu Pro Tyr Gln 
            100                 105                 110         


Ala Glu Phe Leu Val Arg Ser His Asp Ala Glu Glu Val Leu Pro Ser 
        115                 120                 125             


Thr Pro Ala Ser Arg Phe Leu Ser Ala Leu Gly Gly Leu Trp Glu Pro 
    130                 135                 140                 


Gly Glu Leu Gln Leu Leu Asn Val Thr Ser Ala Leu Asp Arg Gly Gly 
145                 150                 155                 160 


Arg Val Pro Leu Pro Ile Glu Gly Arg Lys Glu Gly Val Tyr Ile Lys 
                165                 170                 175     


Val Gly Ser Ala Ser Pro Phe Ser Thr Cys Leu Lys Met Val Ala Ser 
            180                 185                 190         


Pro Asp Ser His Ala Arg Cys Ala Gln Gly Gln Pro Pro Leu Leu Ser 
        195                 200                 205             


Cys Tyr Asp Thr Leu Ala Pro His Phe Arg Val Asp Trp Cys Asn Val 
    210                 215                 220                 


Thr Leu Val Asp Lys Ser Val Pro Glu Pro Ala Asp Glu Val Pro Thr 
225                 230                 235                 240 


Pro Gly Asp Gly Ile Leu Glu His Asp Pro Phe Phe Cys Pro Pro Thr 
                245                 250                 255     


Glu Ala Pro Asp Arg Asp Phe Leu Val Asp Ala 
            260                 265         


<210>  2440
<211>  521
<212>  PRT
<213>  Homo Sapiens

<400>  2440

Ala Ser Glu Gly Gly Phe Thr Ala Thr Gly Gln Arg Gln Leu Arg Pro 
1               5                   10                  15      


Glu His Phe Gln Glu Val Gly Tyr Ala Ala Pro Pro Ser Pro Pro Leu 
            20                  25                  30          


Ser Arg Ser Leu Pro Met Asp His Pro Asp Ser Ser Gln His Gly Pro 
        35                  40                  45              


Pro Phe Glu Gly Gln Ser Gln Val Gln Pro Pro Pro Ser Gln Glu Ala 
    50                  55                  60                  


Thr Pro Leu Gln Gln Glu Lys Leu Leu Pro Ala Gln Leu Pro Ala Glu 
65                  70                  75                  80  


Lys Glu Val Gly Pro Pro Leu Pro Gln Glu Ala Val Pro Leu Gln Lys 
                85                  90                  95      


Glu Leu Pro Ser Leu Gln His Pro Asn Glu Gln Lys Glu Gly Met Pro 
            100                 105                 110         


Ala Pro Phe Gly Asp Gln Ser His Pro Glu Pro Glu Ser Trp Asn Ala 
        115                 120                 125             


Ala Gln His Cys Gln Gln Asp Arg Ser Gln Gly Gly Trp Gly His Arg 
    130                 135                 140                 


Leu Asp Gly Phe Pro Pro Gly Arg Pro Ser Pro Asp Asn Leu Asn Gln 
145                 150                 155                 160 


Ile Cys Leu Pro Asn Arg Gln His Val Val Tyr Gly Pro Trp Asn Leu 
                165                 170                 175     


Pro Gln Ser Ser Tyr Ser His Leu Thr Arg Gln Gly Glu Thr Leu Asn 
            180                 185                 190         


Phe Leu Glu Ile Gly Tyr Ser Arg Cys Cys His Cys Arg Ser His Thr 
        195                 200                 205             


Asn Arg Leu Glu Cys Ala Lys Leu Val Trp Glu Glu Ala Met Ser Arg 
    210                 215                 220                 


Phe Cys Glu Ala Glu Phe Ser Val Lys Thr Arg Pro His Trp Cys Cys 
225                 230                 235                 240 


Thr Arg Gln Gly Glu Ala Arg Phe Ser Cys Phe Gln Glu Glu Ala Pro 
                245                 250                 255     


Gln Pro His Tyr Gln Leu Arg Ala Cys Pro Ser His Gln Pro Asp Ile 
            260                 265                 270         


Ser Ser Gly Leu Glu Leu Pro Phe Pro Pro Gly Val Pro Thr Leu Asp 
        275                 280                 285             


Asn Ile Lys Asn Ile Cys His Leu Arg Arg Phe Arg Ser Val Pro Arg 
    290                 295                 300                 


Asn Leu Pro Ala Thr Asp Pro Leu Gln Arg Glu Leu Leu Ala Leu Ile 
305                 310                 315                 320 


Gln Leu Glu Arg Glu Phe Gln Arg Cys Cys Arg Gln Gly Asn Asn His 
                325                 330                 335     


Thr Cys Thr Trp Lys Ala Trp Glu Asp Thr Leu Asp Lys Tyr Cys Asp 
            340                 345                 350         


Arg Glu Tyr Ala Val Lys Thr His His His Leu Cys Cys Arg His Pro 
        355                 360                 365             


Pro Ser Pro Thr Arg Asp Glu Cys Phe Ala Arg Arg Ala Pro Tyr Pro 
    370                 375                 380                 


Asn Tyr Asp Arg Asp Ile Leu Thr Ile Asp Ile Ser Arg Val Thr Pro 
385                 390                 395                 400 


Asn Leu Met Gly His Leu Cys Gly Asn Gln Arg Val Leu Thr Lys His 
                405                 410                 415     


Lys His Ile Pro Gly Leu Ile His Asn Met Thr Ala Arg Cys Cys Asp 
            420                 425                 430         


Leu Pro Phe Pro Glu Gln Ala Cys Cys Ala Glu Glu Glu Lys Leu Thr 
        435                 440                 445             


Phe Ile Asn Asp Leu Cys Gly Pro Arg Arg Asn Ile Trp Arg Asp Pro 
    450                 455                 460                 


Ala Leu Cys Cys Tyr Leu Ser Pro Gly Asp Glu Gln Val Asn Cys Phe 
465                 470                 475                 480 


Asn Ile Asn Tyr Leu Arg Asn Val Ala Leu Val Ser Gly Asp Thr Glu 
                485                 490                 495     


Asn Ala Lys Gly Gln Gly Glu Gln Gly Ser Thr Gly Gly Thr Asn Ile 
            500                 505                 510         


Ser Ser Thr Ser Glu Pro Lys Glu Glu 
        515                 520     


<210>  2441
<211>  287
<212>  PRT
<213>  Homo Sapiens

<400>  2441

Ala Glu Ala Pro Cys Gly Val Ala Pro Gln Ala Arg Ile Thr Gly Gly 
1               5                   10                  15      


Ser Ser Ala Val Ala Gly Gln Trp Pro Trp Gln Val Ser Ile Thr Tyr 
            20                  25                  30          


Glu Gly Val His Val Cys Gly Gly Ser Leu Val Ser Glu Gln Trp Val 
        35                  40                  45              


Leu Ser Ala Ala His Cys Phe Pro Ser Glu His His Lys Glu Ala Tyr 
    50                  55                  60                  


Glu Val Lys Leu Gly Ala His Gln Leu Asp Ser Tyr Ser Glu Asp Ala 
65                  70                  75                  80  


Lys Val Ser Thr Leu Lys Asp Ile Ile Pro His Pro Ser Tyr Leu Gln 
                85                  90                  95      


Glu Gly Ser Gln Gly Asp Ile Ala Leu Leu Gln Leu Ser Arg Pro Ile 
            100                 105                 110         


Thr Phe Ser Arg Tyr Ile Arg Pro Ile Cys Leu Pro Ala Ala Asn Ala 
        115                 120                 125             


Ser Phe Pro Asn Gly Leu His Cys Thr Val Thr Gly Trp Gly His Val 
    130                 135                 140                 


Ala Pro Ser Val Ser Leu Leu Thr Pro Lys Pro Leu Gln Gln Leu Glu 
145                 150                 155                 160 


Val Pro Leu Ile Ser Arg Glu Thr Cys Asn Cys Leu Tyr Asn Ile Asp 
                165                 170                 175     


Ala Lys Pro Glu Glu Pro His Phe Val Gln Glu Asp Met Val Cys Ala 
            180                 185                 190         


Gly Tyr Val Glu Gly Gly Lys Asp Ala Cys Gln Gly Asp Ser Gly Gly 
        195                 200                 205             


Pro Leu Ser Cys Pro Val Glu Gly Leu Trp Tyr Leu Thr Gly Ile Val 
    210                 215                 220                 


Ser Trp Gly Asp Ala Cys Gly Ala Arg Asn Arg Pro Gly Val Tyr Thr 
225                 230                 235                 240 


Leu Ala Ser Ser Tyr Ala Ser Trp Ile Gln Ser Lys Val Thr Glu Leu 
                245                 250                 255     


Gln Pro Arg Val Val Pro Gln Thr Gln Glu Ser Gln Pro Asp Ser Asn 
            260                 265                 270         


Leu Cys Gly Ser His Leu Ala Phe Ser Ser Ala Pro Ala Gln Gly 
        275                 280                 285         


<210>  2442
<211>  132
<212>  PRT
<213>  Homo Sapiens

<400>  2442

Pro Pro Asn Arg Arg Thr Cys Val Phe Phe Glu Ala Pro Gly Val Arg 
1               5                   10                  15      


Gly Ser Thr Lys Thr Leu Gly Glu Leu Leu Asp Thr Gly Thr Glu Leu 
            20                  25                  30          


Pro Arg Ala Ile Arg Cys Leu Tyr Ser Arg Cys Cys Phe Gly Ile Trp 
        35                  40                  45              


Asn Leu Thr Gln Asp Arg Ala Gln Val Glu Met Gln Gly Cys Arg Asp 
    50                  55                  60                  


Ser Asp Glu Pro Gly Cys Glu Ser Leu His Cys Asp Pro Ser Pro Arg 
65                  70                  75                  80  


Ala His Pro Ser Pro Gly Ser Thr Leu Phe Thr Cys Ser Cys Gly Thr 
                85                  90                  95      


Asp Phe Cys Asn Ala Asn Tyr Ser His Leu Pro Pro Pro Gly Ser Pro 
            100                 105                 110         


Gly Thr Pro Gly Ser Gln Gly Pro Gln Ala Ala Pro Gly Glu Ser Ile 
        115                 120                 125             


Trp Met Ala Leu 
    130         


<210>  2443
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  2443

Gly Pro Met Pro Lys Leu Ala Asp Arg Lys Leu Cys Ala Asp Gln Glu 
1               5                   10                  15      


Cys Ser His Pro Ile Ser Met Ala Val Ala Leu Gln Asp Tyr Met Ala 
            20                  25                  30          


Pro Asp Cys Arg Phe Leu Thr Ile His Arg Gly Gln Val Val Tyr Val 
        35                  40                  45              


Phe Ser Lys Leu Lys Gly Arg Gly Arg Leu Phe Trp Gly Gly Ser Val 
    50                  55                  60                  


Gln Gly Asp Tyr Tyr Gly Asp Leu Ala Ala Arg Leu Gly Tyr Phe Pro 
65                  70                  75                  80  


Ser Ser Ile Val Arg Glu Asp Gln Thr Leu Lys Pro Gly Lys Val Asp 
                85                  90                  95      


Val Lys Thr Asp Lys Trp Asp Phe Tyr Cys Gln 
            100                 105         


<210>  2444
<211>  333
<212>  PRT
<213>  Homo Sapiens

<400>  2444

Val Ser Pro Ser Ala Ser Ala Trp Pro Glu Glu Lys Asn Tyr His Gln 
1               5                   10                  15      


Pro Ala Ile Leu Asn Ser Ser Ala Leu Arg Gln Ile Ala Glu Gly Thr 
            20                  25                  30          


Ser Ile Ser Glu Met Trp Gln Asn Asp Leu Gln Pro Leu Leu Ile Glu 
        35                  40                  45              


Arg Tyr Pro Gly Ser Pro Gly Ser Tyr Ala Ala Arg Gln His Ile Met 
    50                  55                  60                  


Gln Arg Ile Gln Arg Leu Gln Ala Asp Trp Val Leu Glu Ile Asp Thr 
65                  70                  75                  80  


Phe Leu Ser Gln Thr Pro Tyr Gly Tyr Arg Ser Phe Ser Asn Ile Ile 
                85                  90                  95      


Ser Thr Leu Asn Pro Thr Ala Lys Arg His Leu Val Leu Ala Cys His 
            100                 105                 110         


Tyr Asp Ser Lys Tyr Phe Ser His Trp Asn Asn Arg Val Phe Val Gly 
        115                 120                 125             


Ala Thr Asp Ser Ala Val Pro Cys Ala Met Met Leu Glu Leu Ala Arg 
    130                 135                 140                 


Ala Leu Asp Lys Lys Leu Leu Ser Leu Lys Thr Val Ser Asp Ser Lys 
145                 150                 155                 160 


Pro Asp Leu Ser Leu Gln Leu Ile Phe Phe Asp Gly Glu Glu Ala Phe 
                165                 170                 175     


Leu His Trp Ser Pro Gln Asp Ser Leu Tyr Gly Ser Arg His Leu Ala 
            180                 185                 190         


Ala Lys Met Ala Ser Thr Pro His Pro Pro Gly Ala Arg Gly Thr Ser 
        195                 200                 205             


Gln Leu His Gly Met Asp Leu Leu Val Leu Leu Asp Leu Ile Gly Ala 
    210                 215                 220                 


Pro Asn Pro Thr Phe Pro Asn Phe Phe Pro Asn Ser Ala Arg Trp Phe 
225                 230                 235                 240 


Glu Arg Leu Gln Ala Ile Glu His Glu Leu His Glu Leu Gly Leu Leu 
                245                 250                 255     


Lys Asp His Ser Leu Glu Gly Arg Tyr Phe Gln Asn Tyr Ser Tyr Gly 
            260                 265                 270         


Gly Val Ile Gln Asp Asp His Ile Pro Phe Leu Arg Arg Gly Val Pro 
        275                 280                 285             


Val Leu His Leu Ile Pro Ser Pro Phe Pro Glu Val Trp His Thr Met 
    290                 295                 300                 


Asp Asp Asn Glu Glu Asn Leu Asp Glu Ser Thr Ile Asp Asn Leu Asn 
305                 310                 315                 320 


Lys Ile Leu Gln Val Phe Val Leu Glu Tyr Leu His Leu 
                325                 330             


<210>  2445
<211>  377
<212>  PRT
<213>  Homo Sapiens

<400>  2445

Gln Arg Leu Pro Arg Met Gln Glu Asp Ser Pro Leu Gly Gly Gly Ser 
1               5                   10                  15      


Ser Gly Glu Asp Asp Pro Leu Gly Glu Glu Asp Leu Pro Ser Glu Glu 
            20                  25                  30          


Asp Ser Pro Arg Glu Glu Asp Pro Pro Gly Glu Glu Asp Leu Pro Gly 
        35                  40                  45              


Glu Glu Asp Leu Pro Gly Glu Glu Asp Leu Pro Glu Val Lys Pro Lys 
    50                  55                  60                  


Ser Glu Glu Glu Gly Ser Leu Lys Leu Glu Asp Leu Pro Thr Val Glu 
65                  70                  75                  80  


Ala Pro Gly Asp Pro Gln Glu Pro Gln Asn Asn Ala His Arg Asp Lys 
                85                  90                  95      


Glu Gly Asp Asp Gln Ser His Trp Arg Tyr Gly Gly Asp Pro Pro Trp 
            100                 105                 110         


Pro Arg Val Ser Pro Ala Cys Ala Gly Arg Phe Gln Ser Pro Val Asp 
        115                 120                 125             


Ile Arg Pro Gln Leu Ala Ala Phe Cys Pro Ala Leu Arg Pro Leu Glu 
    130                 135                 140                 


Leu Leu Gly Phe Gln Leu Pro Pro Leu Pro Glu Leu Arg Leu Arg Asn 
145                 150                 155                 160 


Asn Gly His Ser Val Gln Leu Thr Leu Pro Pro Gly Leu Glu Met Ala 
                165                 170                 175     


Leu Gly Pro Gly Arg Glu Tyr Arg Ala Leu Gln Leu His Leu His Trp 
            180                 185                 190         


Gly Ala Ala Gly Arg Pro Gly Ser Glu His Thr Val Glu Gly His Arg 
        195                 200                 205             


Phe Pro Ala Glu Ile His Val Val His Leu Ser Thr Ala Phe Ala Arg 
    210                 215                 220                 


Val Asp Glu Ala Leu Gly Arg Pro Gly Gly Leu Ala Val Leu Ala Ala 
225                 230                 235                 240 


Phe Leu Glu Glu Gly Pro Glu Glu Asn Ser Ala Tyr Glu Gln Leu Leu 
                245                 250                 255     


Ser Arg Leu Glu Glu Ile Ala Glu Glu Gly Ser Glu Thr Gln Val Pro 
            260                 265                 270         


Gly Leu Asp Ile Ser Ala Leu Leu Pro Ser Asp Phe Ser Arg Tyr Phe 
        275                 280                 285             


Gln Tyr Glu Gly Ser Leu Thr Thr Pro Pro Cys Ala Gln Gly Val Ile 
    290                 295                 300                 


Trp Thr Val Phe Asn Gln Thr Val Met Leu Ser Ala Lys Gln Leu His 
305                 310                 315                 320 


Thr Leu Ser Asp Thr Leu Trp Gly Pro Gly Asp Ser Arg Leu Gln Leu 
                325                 330                 335     


Asn Phe Arg Ala Thr Gln Pro Leu Asn Gly Arg Val Ile Glu Ala Ser 
            340                 345                 350         


Phe Pro Ala Gly Val Asp Ser Ser Pro Arg Ala Ala Glu Pro Val Gln 
        355                 360                 365             


Leu Asn Ser Cys Leu Ala Ala Gly Asp 
    370                 375         


<210>  2446
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2446

Lys Ala Gln Val Asn Pro Ala Ile Cys Arg Tyr Pro Leu Gly Met Ser 
1               5                   10                  15      


Gly Gly Gln Ile Pro Asp Glu Asp Ile Thr Ala Ser Ser Gln Trp Ser 
            20                  25                  30          


Glu Ser Thr Ala Ala Lys Tyr Gly Arg Leu Asp Ser Glu Glu Gly Asp 
        35                  40                  45              


Gly Ala Trp Cys Pro Glu Ile Pro Val Glu Pro Asp Asp Leu Lys Glu 
    50                  55                  60                  


Phe Leu Gln Ile Asp Leu His Thr Leu His Phe Ile Thr Leu Val Gly 
65                  70                  75                  80  


Thr Gln Gly Arg His Ala Gly Gly His Gly Ile Glu Phe Ala Pro Met 
                85                  90                  95      


Tyr Lys Ile Asn Tyr Ser Arg Asp Gly Thr Arg Trp Ile Ser Trp Arg 
            100                 105                 110         


Asn Arg His Gly Lys Gln Val Leu Asp Gly Asn Ser Asn Pro Tyr Asp 
        115                 120                 125             


Ile Phe Leu Lys Asp Leu Glu Pro Pro Ile Val Ala Arg Phe Val Arg 
    130                 135                 140                 


Phe Ile Pro Val Thr Asp His Ser Met Asn Val Cys Met Arg Val Glu 
145                 150                 155                 160 


Leu Tyr Gly Cys Val Trp Leu Asp Gly Leu Val Ser Tyr Asn Ala Pro 
                165                 170                 175     


Ala Gly Gln Gln Phe Val Leu Pro Gly Gly Ser Ile Ile Tyr Leu Asn 
            180                 185                 190         


Asp Ser Val Tyr Asp Gly Ala Val Gly Tyr Ser Met Thr Glu Gly Leu 
        195                 200                 205             


Gly Gln Leu Thr Asp Gly Val Ser Gly Leu Asp Asp Phe Thr Gln Thr 
    210                 215                 220                 


His Glu Tyr His Val Trp Pro Gly Tyr Asp Tyr Val Gly Trp Arg Asn 
225                 230                 235                 240 


Glu Ser Ala Thr Asn Gly Tyr Ile Glu Ile Met Phe Glu Phe Asp Arg 
                245                 250                 255     


Ile Arg Asn Phe Thr Thr Met Lys Val His Cys Asn Asn Met Phe Ala 
            260                 265                 270         


Lys Gly Val Lys Ile Phe Lys Glu Val Gln Cys Tyr Phe Arg Ser Glu 
        275                 280                 285             


Ala Ser Glu Trp Glu Pro Asn Ala Ile Ser Phe Pro Leu Val Leu Asp 
    290                 295                 300                 


Asp Val Asn Pro Ser Ala Arg Phe Val Thr Val Pro Leu His His Arg 
305                 310                 315                 320 


Met Ala Ser Ala Ile Lys Cys Gln Tyr His Phe Ala Asp Thr Trp Met 
                325                 330                 335     


Met Phe Ser Glu Ile Thr Phe Gln Ser Asp Ala Ala Met Tyr Asn Asn 
            340                 345                 350         


Ser Glu Ala Leu Pro Thr Ser Pro Met Ala Pro Thr Thr Tyr Asp Pro 
        355                 360                 365             


Met Leu Lys Val Asp Asp Ser Asn Thr Arg 
    370                 375             


<210>  2447
<211>  737
<212>  PRT
<213>  Homo Sapiens

<400>  2447

Gly Arg Gly Gly Asp Gly Gly Glu Pro Ser Gln Leu Pro His Cys Pro 
1               5                   10                  15      


Ser Val Ser Pro Ser Ala Gln Pro Trp Thr His Pro Gly Gln Ser Gln 
            20                  25                  30          


Leu Phe Ala Asp Leu Ser Arg Glu Glu Leu Thr Ala Val Met Arg Phe 
        35                  40                  45              


Leu Thr Gln Arg Leu Gly Pro Gly Leu Val Asp Ala Ala Gln Ala Arg 
    50                  55                  60                  


Pro Ser Asp Asn Cys Val Phe Ser Val Glu Leu Gln Leu Pro Pro Lys 
65                  70                  75                  80  


Ala Ala Ala Leu Ala His Leu Asp Arg Gly Ser Pro Pro Pro Ala Arg 
                85                  90                  95      


Glu Ala Leu Ala Ile Val Phe Phe Gly Arg Gln Pro Gln Pro Asn Val 
            100                 105                 110         


Ser Glu Leu Val Val Gly Pro Leu Pro His Pro Ser Tyr Met Arg Asp 
        115                 120                 125             


Val Thr Val Glu Arg His Gly Gly Pro Leu Pro Tyr His Arg Arg Pro 
    130                 135                 140                 


Val Leu Phe Gln Glu Tyr Leu Asp Ile Asp Gln Met Ile Phe Asn Arg 
145                 150                 155                 160 


Glu Leu Pro Gln Ala Ser Gly Leu Leu His His Cys Cys Phe Tyr Lys 
                165                 170                 175     


His Arg Gly Arg Asn Leu Val Thr Met Thr Thr Ala Pro Arg Gly Leu 
            180                 185                 190         


Gln Ser Gly Asp Arg Ala Thr Trp Phe Gly Leu Tyr Tyr Asn Ile Ser 
        195                 200                 205             


Gly Ala Gly Phe Phe Leu His His Val Gly Leu Glu Leu Leu Val Asn 
    210                 215                 220                 


His Lys Ala Leu Asp Pro Ala Arg Trp Thr Ile Gln Lys Val Phe Tyr 
225                 230                 235                 240 


Gln Gly Arg Tyr Tyr Asp Ser Leu Ala Gln Leu Glu Ala Gln Phe Glu 
                245                 250                 255     


Ala Gly Leu Val Asn Val Val Leu Ile Pro Asp Asn Gly Thr Gly Gly 
            260                 265                 270         


Ser Trp Ser Leu Lys Ser Pro Val Pro Pro Gly Pro Ala Pro Pro Leu 
        275                 280                 285             


Gln Phe Tyr Pro Gln Gly Pro Arg Phe Ser Val Gln Gly Ser Arg Val 
    290                 295                 300                 


Ala Ser Ser Leu Trp Thr Phe Ser Phe Gly Leu Gly Ala Phe Ser Gly 
305                 310                 315                 320 


Pro Arg Ile Phe Asp Val Arg Phe Gln Gly Glu Arg Leu Val Tyr Glu 
                325                 330                 335     


Ile Ser Leu Gln Glu Ala Leu Ala Ile Tyr Gly Gly Asn Ser Pro Ala 
            340                 345                 350         


Ala Met Thr Thr Arg Tyr Val Asp Gly Gly Phe Gly Met Gly Lys Tyr 
        355                 360                 365             


Thr Thr Pro Leu Thr Arg Gly Val Asp Cys Pro Tyr Leu Ala Thr Tyr 
    370                 375                 380                 


Val Asp Trp His Phe Leu Leu Glu Ser Gln Ala Pro Lys Thr Ile Arg 
385                 390                 395                 400 


Asp Ala Phe Cys Val Phe Glu Gln Asn Gln Gly Leu Pro Leu Arg Arg 
                405                 410                 415     


His His Ser Asp Leu Tyr Ser His Tyr Phe Gly Gly Leu Ala Glu Thr 
            420                 425                 430         


Val Leu Val Val Arg Ser Met Ser Thr Leu Leu Asn Tyr Asp Tyr Val 
        435                 440                 445             


Trp Asp Thr Val Phe His Pro Ser Gly Ala Ile Glu Ile Arg Phe Tyr 
    450                 455                 460                 


Ala Thr Gly Tyr Ile Ser Ser Ala Phe Leu Phe Gly Ala Thr Gly Lys 
465                 470                 475                 480 


Tyr Gly Asn Gln Val Ser Glu His Thr Leu Gly Thr Val His Thr His 
                485                 490                 495     


Ser Ala His Phe Lys Val Asp Leu Asp Val Ala Gly Leu Glu Asn Trp 
            500                 505                 510         


Val Trp Ala Glu Asp Met Val Phe Val Pro Met Ala Val Pro Trp Ser 
        515                 520                 525             


Pro Glu His Gln Leu Gln Arg Leu Gln Val Thr Arg Lys Leu Leu Glu 
    530                 535                 540                 


Met Glu Glu Gln Ala Ala Phe Leu Val Gly Ser Ala Thr Pro Arg Tyr 
545                 550                 555                 560 


Leu Tyr Leu Ala Ser Asn His Ser Asn Lys Trp Gly His Pro Arg Gly 
                565                 570                 575     


Tyr Arg Ile Gln Met Leu Ser Phe Ala Gly Glu Pro Leu Pro Gln Asn 
            580                 585                 590         


Ser Ser Met Ala Arg Gly Phe Ser Trp Glu Arg Tyr Gln Leu Ala Val 
        595                 600                 605             


Thr Gln Arg Lys Glu Glu Glu Pro Ser Ser Ser Ser Val Phe Asn Gln 
    610                 615                 620                 


Asn Asp Pro Trp Ala Pro Thr Val Asp Phe Ser Asp Phe Ile Asn Asn 
625                 630                 635                 640 


Glu Thr Ile Ala Gly Lys Asp Leu Val Ala Trp Val Thr Ala Gly Phe 
                645                 650                 655     


Leu His Ile Pro His Ala Glu Asp Ile Pro Asn Thr Val Thr Val Gly 
            660                 665                 670         


Asn Gly Val Gly Phe Phe Leu Arg Pro Tyr Asn Phe Phe Asp Glu Asp 
        675                 680                 685             


Pro Ser Phe Tyr Ser Ala Asp Ser Ile Tyr Phe Arg Gly Asp Gln Asp 
    690                 695                 700                 


Ala Gly Ala Cys Glu Val Asn Pro Leu Ala Cys Leu Pro Gln Ala Ala 
705                 710                 715                 720 


Ala Cys Ala Pro Asp Leu Pro Ala Phe Ser His Gly Gly Phe Ser His 
                725                 730                 735     


Asn 
    


<210>  2448
<211>  777
<212>  PRT
<213>  Homo Sapiens

<400>  2448

Thr Lys Asp Ile Ser Ile Asn Ile Tyr His Ser Glu Thr Lys Asp Ile 
1               5                   10                  15      


Asp Asn Pro Pro Arg Asn Glu Thr Thr Glu Ser Thr Glu Lys Met Tyr 
            20                  25                  30          


Lys Met Ser Thr Met Arg Arg Ile Phe Asp Leu Ala Lys His Arg Thr 
        35                  40                  45              


Lys Arg Ser Ala Phe Phe Pro Thr Gly Val Lys Val Cys Pro Gln Glu 
    50                  55                  60                  


Ser Met Lys Gln Ile Leu Asp Ser Leu Gln Ala Tyr Tyr Arg Leu Arg 
65                  70                  75                  80  


Val Cys Gln Glu Ala Val Trp Glu Ala Tyr Arg Ile Phe Leu Asp Arg 
                85                  90                  95      


Ile Pro Asp Thr Gly Glu Tyr Gln Asp Trp Val Ser Ile Cys Gln Gln 
            100                 105                 110         


Glu Thr Phe Cys Leu Phe Asp Ile Gly Lys Asn Phe Ser Asn Ser Gln 
        115                 120                 125             


Glu His Leu Asp Leu Leu Gln Gln Arg Ile Lys Gln Arg Ser Phe Pro 
    130                 135                 140                 


Asp Arg Lys Asp Glu Ile Ser Ala Glu Lys Thr Leu Gly Glu Pro Gly 
145                 150                 155                 160 


Glu Thr Ile Val Ile Ser Thr Asp Val Ala Asn Val Ser Leu Gly Pro 
                165                 170                 175     


Phe Pro Leu Thr Pro Asp Asp Thr Leu Leu Asn Glu Ile Leu Asp Asn 
            180                 185                 190         


Thr Leu Asn Asp Thr Lys Met Pro Thr Thr Glu Arg Glu Thr Glu Phe 
        195                 200                 205             


Ala Val Leu Glu Glu Gln Arg Val Glu Leu Ser Val Ser Leu Val Asn 
    210                 215                 220                 


Gln Lys Phe Lys Ala Glu Leu Ala Asp Ser Gln Ser Pro Tyr Tyr Gln 
225                 230                 235                 240 


Glu Leu Ala Gly Lys Ser Gln Leu Gln Met Gln Lys Ile Phe Lys Lys 
                245                 250                 255     


Leu Pro Gly Phe Lys Lys Ile His Val Leu Gly Phe Arg Pro Lys Lys 
            260                 265                 270         


Glu Lys Asp Gly Ser Ser Ser Thr Glu Met Gln Leu Thr Ala Ile Phe 
        275                 280                 285             


Lys Arg His Ser Ala Glu Ala Lys Ser Pro Ala Ser Asp Leu Leu Ser 
    290                 295                 300                 


Phe Asp Ser Asn Lys Ile Glu Ser Glu Glu Val Tyr His Gly Thr Met 
305                 310                 315                 320 


Glu Glu Asp Lys Gln Pro Glu Ile Tyr Leu Thr Ala Thr Asp Leu Lys 
                325                 330                 335     


Arg Leu Ile Ser Lys Ala Leu Glu Glu Glu Gln Ser Leu Asp Val Gly 
            340                 345                 350         


Thr Ile Gln Phe Thr Asp Glu Ile Ala Gly Ser Leu Pro Ala Phe Gly 
        355                 360                 365             


Pro Asp Thr Gln Ser Glu Leu Pro Thr Ser Phe Ala Val Ile Thr Glu 
    370                 375                 380                 


Asp Ala Thr Leu Ser Pro Glu Leu Pro Pro Val Glu Pro Gln Leu Glu 
385                 390                 395                 400 


Thr Val Asp Gly Ala Glu His Gly Leu Pro Asp Thr Ser Trp Ser Pro 
                405                 410                 415     


Pro Ala Met Ala Ser Thr Ser Leu Ser Glu Ala Pro Pro Phe Phe Met 
            420                 425                 430         


Ala Ser Ser Ile Phe Ser Leu Thr Asp Gln Gly Thr Thr Asp Thr Met 
        435                 440                 445             


Ala Thr Asp Gln Thr Met Leu Val Pro Gly Leu Thr Ile Pro Thr Ser 
    450                 455                 460                 


Asp Tyr Ser Ala Ile Ser Gln Leu Ala Leu Gly Ile Ser His Pro Pro 
465                 470                 475                 480 


Ala Ser Ser Asp Asp Ser Arg Ser Ser Ala Gly Gly Glu Asp Met Val 
                485                 490                 495     


Arg Asp Leu Asp Glu Met Asp Leu Ser Asp Thr Pro Ala Pro Ser Glu 
            500                 505                 510         


Val Pro Glu Leu Ser Glu Tyr Val Ser Val Pro Asp His Phe Leu Glu 
        515                 520                 525             


Asp Thr Thr Pro Val Ser Ala Leu Gln Tyr Ile Thr Thr Ser Ser Met 
    530                 535                 540                 


Thr Ile Ala Pro Lys Gly Arg Glu Leu Val Val Phe Phe Ser Leu Arg 
545                 550                 555                 560 


Val Ala Asn Met Ala Phe Ser Asn Asp Leu Phe Asn Lys Ser Ser Leu 
                565                 570                 575     


Glu Tyr Arg Ala Leu Glu Gln Gln Phe Thr Gln Leu Leu Val Pro Tyr 
            580                 585                 590         


Leu Arg Ser Asn Leu Thr Gly Phe Lys Gln Leu Glu Ile Leu Asn Phe 
        595                 600                 605             


Arg Asn Gly Ser Val Ile Val Asn Ser Lys Met Lys Phe Ala Lys Ser 
    610                 615                 620                 


Val Pro Tyr Asn Leu Thr Lys Ala Val His Gly Val Leu Glu Asp Phe 
625                 630                 635                 640 


Arg Ser Ala Ala Ala Gln Gln Leu His Leu Glu Ile Asp Ser Tyr Ser 
                645                 650                 655     


Leu Asn Ile Glu Pro Ala Asp Gln Ala Asp Pro Cys Lys Phe Leu Ala 
            660                 665                 670         


Cys Gly Glu Phe Ala Gln Cys Val Lys Asn Glu Trp Thr Glu Glu Ala 
        675                 680                 685             


Glu Cys Arg Cys Lys Pro Gly Tyr Asp Ser Gln Gly Ser Leu Asp Gly 
    690                 695                 700                 


Leu Glu Pro Gly Leu Cys Gly Pro Gly Thr Lys Glu Cys Glu Val Leu 
705                 710                 715                 720 


Gln Gly Lys Gly Ala Pro Cys Arg Leu Pro Asp His Ser Glu Asn Gln 
                725                 730                 735     


Ala Tyr Lys Thr Ser Val Lys Lys Phe Gln Asn Gln Gln Asn Asn Lys 
            740                 745                 750         


Val Ile Ser Lys Arg Asn Ser Glu Leu Leu Thr Val Glu Tyr Glu Glu 
        755                 760                 765             


Phe Asn His Gln Asp Trp Glu Gly Asn 
    770                 775         


<210>  2449
<211>  450
<212>  PRT
<213>  Homo Sapiens

<400>  2449

Lys Glu Val Cys Tyr Glu Arg Leu Gly Cys Phe Lys Asp Gly Leu Pro 
1               5                   10                  15      


Trp Thr Arg Thr Phe Ser Thr Glu Leu Val Gly Leu Pro Trp Ser Pro 
            20                  25                  30          


Glu Lys Ile Asn Thr Arg Phe Leu Leu Tyr Thr Ile His Asn Pro Asn 
        35                  40                  45              


Ala Tyr Gln Glu Ile Ser Ala Val Asn Ser Ser Thr Ile Gln Ala Ser 
    50                  55                  60                  


Tyr Phe Gly Thr Asp Lys Ile Thr Arg Ile Asn Ile Ala Gly Trp Lys 
65                  70                  75                  80  


Thr Asp Gly Lys Trp Gln Arg Asp Met Cys Asn Val Leu Leu Gln Leu 
                85                  90                  95      


Glu Asp Ile Asn Cys Ile Asn Leu Asp Trp Ile Asn Gly Ser Arg Glu 
            100                 105                 110         


Tyr Ile His Ala Val Asn Asn Leu Arg Val Val Gly Ala Glu Val Ala 
        115                 120                 125             


Tyr Phe Ile Asp Val Leu Met Lys Lys Phe Glu Tyr Ser Pro Ser Lys 
    130                 135                 140                 


Val His Leu Ile Gly His Ser Leu Gly Ala His Leu Ala Gly Glu Ala 
145                 150                 155                 160 


Gly Ser Arg Ile Pro Gly Leu Gly Arg Ile Thr Gly Leu Asp Pro Ala 
                165                 170                 175     


Gly Pro Phe Phe His Asn Thr Pro Lys Glu Val Arg Leu Asp Pro Ser 
            180                 185                 190         


Asp Ala Asn Phe Val Asp Val Ile His Thr Asn Ala Ala Arg Ile Leu 
        195                 200                 205             


Phe Glu Leu Gly Val Gly Thr Ile Asp Ala Cys Gly His Leu Asp Phe 
    210                 215                 220                 


Tyr Pro Asn Gly Gly Lys His Met Pro Gly Cys Glu Asp Leu Ile Thr 
225                 230                 235                 240 


Pro Leu Leu Lys Phe Asn Phe Asn Ala Tyr Lys Lys Glu Met Ala Ser 
                245                 250                 255     


Phe Phe Asp Cys Asn His Ala Arg Ser Tyr Gln Phe Tyr Ala Glu Ser 
            260                 265                 270         


Ile Leu Asn Pro Asp Ala Phe Ile Ala Tyr Pro Cys Arg Ser Tyr Thr 
        275                 280                 285             


Ser Phe Lys Ala Gly Asn Cys Phe Phe Cys Ser Lys Glu Gly Cys Pro 
    290                 295                 300                 


Thr Met Gly His Phe Ala Asp Arg Phe His Phe Lys Asn Met Lys Thr 
305                 310                 315                 320 


Asn Gly Ser His Tyr Phe Leu Asn Thr Gly Ser Leu Ser Pro Phe Ala 
                325                 330                 335     


Arg Trp Arg His Lys Leu Ser Val Lys Leu Ser Gly Ser Glu Val Thr 
            340                 345                 350         


Gln Gly Thr Val Phe Leu Arg Val Gly Gly Ala Ile Gly Lys Thr Gly 
        355                 360                 365             


Glu Phe Ala Ile Val Ser Gly Lys Leu Glu Pro Gly Met Thr Tyr Thr 
    370                 375                 380                 


Lys Leu Ile Asp Ala Asp Val Asn Val Gly Asn Ile Thr Ser Val Gln 
385                 390                 395                 400 


Phe Ile Trp Lys Lys His Leu Phe Glu Asp Ser Gln Asn Lys Leu Gly 
                405                 410                 415     


Ala Glu Met Val Ile Asn Thr Ser Gly Lys Tyr Gly Tyr Lys Ser Thr 
            420                 425                 430         


Phe Cys Ser Gln Asp Ile Met Gly Pro Asn Ile Leu Gln Asn Leu Lys 
        435                 440                 445             


Pro Cys 
    450 


<210>  2450
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  2450

Gln Pro Thr Met Thr Gln Thr Ser Ser Ser Gln Gly Gly Leu Gly Gly 
1               5                   10                  15      


Leu Ser Leu Thr Thr Glu Pro Val Ser Ser Asn Pro Gly Tyr Ile Pro 
            20                  25                  30          


Ser Ser Glu Ala Asn Arg Pro Ser His Leu Ser Ser Thr Gly Thr Pro 
        35                  40                  45              


Gly Ala Gly Val Pro Ser Ser Gly Arg Asp Gly Gly Thr Ser Arg Asp 
    50                  55                  60                  


Thr Phe Gln Thr Val Pro Pro Asn Ser Thr Thr Met Ser Leu Ser Met 
65                  70                  75                  80  


Arg Glu Asp Ala Thr Ile Leu Pro Ser Pro Thr Ser Glu Thr Val Leu 
                85                  90                  95      


Thr Val Ala Ala 
            100 


<210>  2451
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  2451

Ser Ser Glu Trp Ser Val Gly Gln Val Ser Thr Asn Thr Ser Tyr Lys 
1               5                   10                  15      


Ala Phe Ser Ser Glu Trp Ile Ser Ala Asp Ile Gly Leu Gln Val Gly 
            20                  25                  30          


Leu Gly Gly Val Asn Ile Thr Leu Thr Gly Thr Pro Val Gln Gln Leu 
        35                  40                  45              


Asn Glu Thr Ile Asn Tyr Asn Glu Glu Phe Thr Trp Arg Leu Gly Glu 
    50                  55                  60                  


Asn Tyr Ala Glu Glu Tyr Ala Lys Ala Leu Glu Lys Gly Leu Pro Asp 
65                  70                  75                  80  


Pro Val Leu Tyr Leu Ala Glu Lys Phe Thr Pro Arg Ser Pro Cys Gly 
                85                  90                  95      


Leu Tyr Arg Gln Tyr Arg Leu Ala Gly His Tyr Thr Ser Ala Met 
            100                 105                 110     


<210>  2452
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  2452

Val Gly Thr Val Asn Thr Asn Thr Ser Tyr Lys Ala Phe Ser Ala Ala 
1               5                   10                  15      


Arg Val Thr Ala Arg Val Arg Leu Leu Val Gly Leu Glu Gly Ile Asn 
            20                  25                  30          


Ile Thr Leu Thr Gly Thr Pro Val His Gln Leu Asn Glu Thr Ile Asp 
        35                  40                  45              


Tyr Asn Glu Gln Phe Thr Trp Arg Leu Lys Glu Asn Tyr Ala Ala Glu 
    50                  55                  60                  


Tyr Ala Asn Ala Leu Glu Lys Gly Leu Pro Asp Pro Val Leu Tyr Leu 
65                  70                  75                  80  


Ala Glu Lys Phe Thr Pro Ser Ser Pro Cys Gly Leu Tyr His Gln Tyr 
                85                  90                  95      


His Leu Ala Gly His Tyr Ala Ser Ala Thr 
            100                 105     


<210>  2453
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  2453

Gly Ile Phe Asn Lys Arg Asp Phe Thr Arg Trp Pro Lys Pro Arg Cys 
1               5                   10                  15      


Lys Met Tyr Ile Pro Leu Asp Pro Asp Tyr Asn Ala Asp Cys Pro Asn 
            20                  25                  30          


Val Thr Ala Pro Val Cys Ala Ser Asn Gly His Thr Phe Gln Asn Glu 
        35                  40                  45              


Cys Phe Phe Cys Val Glu Gln Arg Glu Phe His Tyr Arg Ile Lys Phe 
    50                  55                  60                  


Glu Lys Tyr Gly Lys Cys Asp 
65                  70      


<210>  2454
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  2454

His Gly Cys Leu His Cys His Ser Asn Phe Ser Lys Lys Phe Ser Phe 
1               5                   10                  15      


Tyr Arg His His Val Asn Phe Lys Ser Trp Trp Val Gly Asp Ile Pro 
            20                  25                  30          


Val Ser Gly Ala Leu Leu Thr Asp Trp Ser Asp Asp Thr Met Lys Glu 
        35                  40                  45              


Leu His Leu Ala Ile Pro Ala Lys Ile Thr Arg Glu Lys Leu Asp Gln 
    50                  55                  60                  


Val Ala Thr Ala Val Tyr Gln Met Met Asp Gln Leu Tyr Gln Gly Lys 
65                  70                  75                  80  


Met Tyr Phe Pro Gly Tyr Phe Pro Asn Glu Leu Arg Asn Ile Phe Arg 
                85                  90                  95      


Glu Gln Val His Leu Ile Gln Asn Ala Ile Ile Glu Ser Arg Ile Asp 
            100                 105                 110         


Cys Gln His Arg Cys Gly Ile Phe Gln Tyr Glu Thr Ile Ser Cys Asn 
        115                 120                 125             


Asn Cys Thr Asp Ser His Val Ala Cys Phe Gly Tyr Asn Cys Glu Ser 
    130                 135                 140                 


Ser Ala Gln Trp Lys Ser Ala Val Gln Gly Leu Leu Asn Tyr Ile Asn 
145                 150                 155                 160 


Asn Trp His Lys Gln Asp Thr Ser Met Ser Leu Val Ser Pro Ala Leu 
                165                 170                 175     


Arg Cys Leu Glu Pro Pro His Leu Ala Asn Leu Thr Leu Glu Asp Ala 
            180                 185                 190         


Ala Glu Cys Leu Lys Gln His 
        195                 


<210>  2455
<211>  817
<212>  PRT
<213>  Homo Sapiens

<400>  2455

Cys Gly Gln Ala Pro Leu Asp Pro Val Tyr Leu Pro Ala Ala Leu Glu 
1               5                   10                  15      


Leu Leu Asp Ala Pro Glu His Phe Arg Val Gln Gln Val Gly His Tyr 
            20                  25                  30          


Pro Pro Ala Asn Ser Ser Leu Ser Ser Arg Ser Glu Thr Phe Leu Leu 
        35                  40                  45              


Leu Gln Pro Trp Pro Arg Ala Gln Pro Leu Leu Arg Ala Ser Tyr Pro 
    50                  55                  60                  


Pro Phe Ala Thr Gln Gln Val Val Pro Pro Arg Val Thr Glu Pro His 
65                  70                  75                  80  


Gln Arg Pro Val Pro Trp Asp Val Arg Ala Val Ser Val Glu Ala Ala 
                85                  90                  95      


Val Thr Pro Ala Glu Pro Tyr Ala Arg Val Leu Phe His Leu Lys Gly 
            100                 105                 110         


Gln Asp Trp Pro Pro Gly Ser Gly Ser Leu Pro Cys Ala Arg Leu His 
        115                 120                 125             


Ala Thr His Pro Ala Gly Thr Ala His Gln Ala Cys Arg Phe Gln Pro 
    130                 135                 140                 


Ser Leu Gly Ala Cys Val Val Glu Leu Glu Leu Pro Ser His Trp Phe 
145                 150                 155                 160 


Ser Gln Ala Ser Thr Thr Arg Ala Glu Leu Ala Tyr Thr Leu Glu Pro 
                165                 170                 175     


Ala Ala Glu Gly Pro Gly Gly Cys Gly Ser Gly Glu Glu Asn Asp Pro 
            180                 185                 190         


Gly Glu Gln Ala Leu Pro Val Gly Gly Val Glu Leu Arg Pro Ala Asp 
        195                 200                 205             


Pro Pro Gln Tyr Gln Glu Val Pro Leu Asp Glu Ala Val Thr Leu Arg 
    210                 215                 220                 


Val Pro Asp Met Pro Val Arg Pro Gly Gln Leu Phe Ser Ala Thr Leu 
225                 230                 235                 240 


Leu Leu Arg His Asn Phe Thr Ala Ser Leu Leu Thr Leu Arg Ile Lys 
                245                 250                 255     


Val Lys Lys Gly Leu His Val Thr Ala Ala Arg Pro Ala Gln Pro Thr 
            260                 265                 270         


Leu Trp Thr Ala Lys Leu Asp Arg Phe Lys Gly Ser Arg His His Thr 
        275                 280                 285             


Thr Leu Ile Thr Cys His Arg Ala Gly Leu Thr Glu Pro Asp Ser Ser 
    290                 295                 300                 


Pro Leu Glu Leu Ser Glu Phe Leu Trp Val Asp Phe Val Val Glu Asn 
305                 310                 315                 320 


Ser Thr Gly Gly Gly Val Ala Val Thr Arg Pro Val Thr Trp Gln Leu 
                325                 330                 335     


Glu Tyr Pro Gly Gln Ala Pro Glu Ala Glu Lys Asp Lys Met Val Trp 
            340                 345                 350         


Glu Ile Leu Val Ser Glu Arg Asp Ile Arg Ala Leu Ile Pro Leu Ala 
        355                 360                 365             


Lys Ala Glu Glu Leu Val Asn Thr Ala Pro Leu Thr Gly Val Pro Gln 
    370                 375                 380                 


His Val Pro Val Arg Leu Val Thr Val Asp Gly Gly Gly Ala Leu Val 
385                 390                 395                 400 


Glu Val Thr Glu His Val Gly Cys Glu Ser Ala Asn Thr Gln Val Leu 
                405                 410                 415     


Gln Val Ser Glu Ala Cys Asp Ala Val Phe Val Ala Gly Lys Glu Ser 
            420                 425                 430         


Arg Gly Ala Arg Gly Val Arg Val Asp Phe Trp Trp Arg Arg Leu Arg 
        435                 440                 445             


Ala Ser Leu Arg Leu Thr Val Trp Ala Pro Leu Leu Pro Leu Arg Ile 
    450                 455                 460                 


Glu Leu Thr Asp Thr Thr Leu Glu Gln Val Arg Gly Trp Arg Val Pro 
465                 470                 475                 480 


Gly Pro Ala Glu Gly Pro Ala Glu Pro Ala Ala Glu Ala Ser Asp Glu 
                485                 490                 495     


Ala Glu Arg Arg Ala Arg Gly Cys His Leu Gln Tyr Gln Arg Ala Gly 
            500                 505                 510         


Val Arg Phe Leu Ala Pro Phe Ala Ala His Pro Leu Asp Gly Gly Arg 
        515                 520                 525             


Arg Leu Thr His Leu Leu Gly Pro Asp Trp Leu Leu Asp Val Ser His 
    530                 535                 540                 


Leu Val Ala Pro His Ala Arg Val Leu Asp Ser Arg Val Ala Ser Leu 
545                 550                 555                 560 


Glu Gly Gly Arg Val Val Val Gly Arg Glu Pro Gly Val Thr Ser Ile 
                565                 570                 575     


Glu Val Arg Ser Pro Leu Ser Asp Ser Ile Leu Gly Glu Gln Ala Leu 
            580                 585                 590         


Ala Val Thr Asp Asp Lys Val Ser Val Leu Glu Leu Arg Val Gln Pro 
        595                 600                 605             


Val Met Gly Ile Ser Leu Thr Leu Ser Arg Gly Thr Ala His Pro Gly 
    610                 615                 620                 


Glu Val Thr Ala Thr Cys Trp Ala Gln Ser Ala Leu Pro Ala Pro Lys 
625                 630                 635                 640 


Gln Glu Val Ala Leu Ser Leu Trp Leu Ser Phe Ser Asp His Thr Val 
                645                 650                 655     


Ala Pro Ala Glu Leu Tyr Asp Arg Arg Asp Leu Gly Leu Ser Val Ser 
            660                 665                 670         


Ala Glu Glu Pro Gly Ala Ile Leu Pro Ala Glu Glu Gln Gly Ala Gln 
        675                 680                 685             


Leu Gly Val Val Val Ser Gly Ala Gly Ala Glu Gly Leu Pro Leu His 
    690                 695                 700                 


Val Ala Leu His Pro Pro Glu Pro Cys Arg Arg Gly Arg His Arg Val 
705                 710                 715                 720 


Pro Leu Ala Ser Gly Thr Ala Trp Leu Gly Leu Pro Pro Ala Ser Thr 
                725                 730                 735     


Pro Ala Pro Ala Leu Pro Ser Ser Pro Ala Trp Ser Pro Pro Ala Thr 
            740                 745                 750         


Glu Ala Thr Met Gly Gly Lys Arg Gln Val Ala Gly Ser Val Gly Gly 
        755                 760                 765             


Asn Thr Gly Val Arg Gly Lys Phe Glu Arg Ala Glu Glu Glu Ala Arg 
    770                 775                 780                 


Lys Glu Glu Thr Glu Ala Arg Glu Glu Glu Glu Glu Glu Glu Glu Glu 
785                 790                 795                 800 


Met Val Pro Ala Pro Gln His Val Thr Glu Leu Glu Leu Gly Met Tyr 
                805                 810                 815     


Ala 
    


<210>  2456
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  2456

Leu Asn Arg Arg Lys Lys Gln Val Gly Thr Gly Leu Gly Gly Asn Cys 
1               5                   10                  15      


Thr Gly Cys Ile Ile Cys Ser Glu Glu Asn Gly Cys Ser Thr Cys Gln 
            20                  25                  30          


Gln Arg Leu Phe Leu Phe Ile Arg Arg Glu Gly Ile Arg Gln Tyr Gly 
        35                  40                  45              


Lys Cys Leu His Asp Cys Pro Pro Gly Tyr Phe Gly Ile Arg Gly Gln 
    50                  55                  60                  


Glu Val Asn Arg Cys Lys Lys Cys Gly Ala Thr Cys Glu Ser Cys Phe 
65                  70                  75                  80  


Ser Gln Asp Phe Cys Ile Arg Cys Lys Arg Gln Phe Tyr Leu Tyr Lys 
                85                  90                  95      


Gly Lys Cys Leu Pro Thr Cys Pro Pro Gly Thr Leu Ala His Gln Asn 
            100                 105                 110         


Thr Arg Glu Cys Gln Gly Glu Cys Glu Leu Gly Pro Trp Gly Gly Trp 
        115                 120                 125             


Ser Pro Cys Thr His Asn Gly Lys Thr Cys Gly Ser Ala Trp Gly Leu 
    130                 135                 140                 


Glu Ser Arg Val Arg Glu Ala Gly Arg Ala Gly His Glu Glu Ala Ala 
145                 150                 155                 160 


Thr Cys Gln Val Leu Ser Glu Ser Arg Lys Cys Pro Ile Gln Arg Pro 
                165                 170                 175     


Cys Pro Gly Glu Arg Ser Pro Gly Gln Lys Lys Gly Arg Lys Asp Arg 
            180                 185                 190         


Arg Pro Arg Lys Asp Arg Lys Leu Asp Arg Arg Leu Asp Val Arg Pro 
        195                 200                 205             


Arg Gln Pro Gly Leu Gln Pro 
    210                 215 


<210>  2457
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  2457

Phe Gln Pro Pro Gln Leu Gly Arg Thr Asn Met His Tyr Ser Lys Leu 
1               5                   10                  15      


Pro Arg Thr Ala Ile Glu Thr Glu Phe Lys Gln Asn Val Gly Pro Pro 
            20                  25                  30          


Pro Lys Asp Leu Thr Thr Glu Val Tyr Phe Pro Ser Ile Lys Ser Arg 
        35                  40                  45              


Ser His Leu Pro Ala Val Phe Tyr Asn Gln Tyr Phe Lys His Pro Lys 
    50                  55                  60                  


Cys Val Gly Glu Tyr Gly Pro Lys Asn Gly Ala Glu Arg Gln Ile Glu 
65                  70                  75                  80  


Glu Trp Lys Val Leu Pro Thr Thr Met Met Phe Ser Met Leu Ala Asp 
                85                  90                  95      


Cys Val Leu Lys Ser Thr Pro Ile Pro Ile Leu Gly Val Ala Met 
            100                 105                 110     


<210>  2458
<211>  631
<212>  PRT
<213>  Homo Sapiens

<400>  2458

Glu Met Asp Glu Val Gly Val Gln Lys Cys Lys Asn Ala Leu Lys Leu 
1               5                   10                  15      


Pro Val Leu Glu Val Leu Pro Gly Gly Gly Trp Asp Asn Leu Arg Asn 
            20                  25                  30          


Val Asp Met Gly Arg Val Met Glu Leu Thr Tyr Ser Asn Cys Arg Thr 
        35                  40                  45              


Thr Glu Asp Gly Gln Tyr Ile Ile Pro Asp Glu Ile Phe Thr Ile Pro 
    50                  55                  60                  


Gln Lys Gln Ser Asn Leu Glu Met Asn Ser Glu Ile Leu Glu Ser Trp 
65                  70                  75                  80  


Ala Asn Tyr Gln Ser Ser Thr Ser Tyr Ser Ile Asn Thr Glu Leu Ser 
                85                  90                  95      


Leu Phe Ser Lys Val Asn Gly Lys Phe Ser Thr Glu Phe Gln Arg Met 
            100                 105                 110         


Lys Thr Leu Gln Val Lys Asp Gln Ala Ile Thr Thr Arg Val Gln Val 
        115                 120                 125             


Arg Asn Leu Val Tyr Thr Val Lys Ile Asn Pro Thr Leu Glu Leu Ser 
    130                 135                 140                 


Ser Gly Phe Arg Lys Glu Leu Leu Asp Ile Ser Asp Arg Leu Glu Asn 
145                 150                 155                 160 


Asn Gln Thr Arg Met Ala Thr Tyr Leu Ala Glu Leu Leu Val Leu Asn 
                165                 170                 175     


Tyr Gly Thr His Val Thr Thr Ser Val Asp Ala Gly Ala Ala Leu Ile 
            180                 185                 190         


Gln Glu Asp His Leu Arg Ala Ser Phe Leu Gln Asp Ser Gln Ser Ser 
        195                 200                 205             


Arg Ser Ala Val Thr Ala Ser Ala Gly Leu Ala Phe Gln Asn Thr Val 
    210                 215                 220                 


Asn Phe Lys Phe Glu Glu Asn Tyr Thr Ser Gln Asn Val Leu Thr Lys 
225                 230                 235                 240 


Ser Tyr Leu Ser Asn Arg Thr Asn Ser Arg Val Gln Ser Ile Gly Gly 
                245                 250                 255     


Val Pro Phe Tyr Pro Gly Ile Thr Leu Gln Ala Trp Gln Gln Gly Ile 
            260                 265                 270         


Thr Asn His Leu Val Ala Ile Asp Arg Ser Gly Leu Pro Leu His Phe 
        275                 280                 285             


Phe Ile Asn Pro Asn Met Leu Pro Asp Leu Pro Gly Pro Leu Val Lys 
    290                 295                 300                 


Lys Val Ser Lys Thr Val Glu Thr Ala Val Lys Arg Tyr Tyr Thr Phe 
305                 310                 315                 320 


Asn Thr Tyr Pro Gly Cys Thr Asp Leu Asn Ser Pro Asn Phe Asn Phe 
                325                 330                 335     


Gln Ala Asn Thr Asp Asp Gly Ser Cys Glu Gly Lys Met Thr Asn Phe 
            340                 345                 350         


Ser Phe Gly Gly Val Tyr Gln Glu Cys Thr Gln Leu Ser Gly Asn Arg 
        355                 360                 365             


Asp Val Leu Leu Cys Gln Lys Leu Glu Gln Lys Asn Pro Leu Thr Gly 
    370                 375                 380                 


Asp Phe Ser Cys Pro Ser Gly Tyr Ser Pro Val His Leu Leu Ser Gln 
385                 390                 395                 400 


Ile His Glu Glu Gly Tyr Asn His Leu Glu Cys His Arg Lys Cys Thr 
                405                 410                 415     


Leu Leu Val Phe Cys Lys Thr Val Cys Glu Asp Val Phe Gln Val Ala 
            420                 425                 430         


Lys Ala Glu Phe Arg Ala Phe Trp Cys Val Ala Ser Ser Gln Val Pro 
        435                 440                 445             


Glu Asn Ser Gly Leu Leu Phe Gly Gly Leu Phe Ser Ser Lys Ser Ile 
    450                 455                 460                 


Asn Pro Met Thr Asn Ala Gln Ser Cys Pro Ala Gly Tyr Phe Pro Leu 
465                 470                 475                 480 


Arg Leu Phe Glu Asn Leu Lys Val Cys Val Ser Gln Asp Tyr Glu Leu 
                485                 490                 495     


Gly Ser Arg Phe Ala Val Pro Phe Gly Gly Phe Phe Ser Cys Thr Val 
            500                 505                 510         


Gly Asn Pro Leu Val Asp Pro Ala Ile Ser Arg Asp Leu Gly Ala Leu 
        515                 520                 525             


Ser Leu Lys Lys Cys Pro Gly Gly Phe Ser Gln His Pro Ala Leu Ile 
    530                 535                 540                 


Ser Asp Gly Cys Gln Val Ser Tyr Cys Val Lys Ser Gly Leu Phe Thr 
545                 550                 555                 560 


Gly Gly Ser Leu Pro Pro Ala Arg Leu Pro Pro Phe Thr Arg Pro Pro 
                565                 570                 575     


Leu Met Ser Gln Ala Ala Thr Asn Thr Val Ile Val Thr Asn Ser Glu 
            580                 585                 590         


Asn Ala Arg Ser Trp Ile Lys Asp Ser Gln Thr His Gln Trp Arg Leu 
        595                 600                 605             


Gly Glu Pro Ile Glu Leu Arg Arg Ala Met Asn Val Ile His Gly Asp 
    610                 615                 620                 


Gly Gly Gly Leu Ser Gly Gly 
625                 630     


<210>  2459
<211>  424
<212>  PRT
<213>  Homo Sapiens

<400>  2459

Lys Ser Ile Ser Cys Leu Lys Pro Ala Arg Leu Pro Ile Tyr Gln Arg 
1               5                   10                  15      


Lys Pro Phe Ile Ala Ala Trp Asn Ala Pro Thr Asp Gln Cys Leu Ile 
            20                  25                  30          


Lys Tyr Asn Leu Arg Leu Asn Leu Lys Met Phe Pro Val Ile Gly Ser 
        35                  40                  45              


Pro Leu Ala Lys Ala Arg Gly Gln Asn Val Thr Ile Phe Tyr Val Asn 
    50                  55                  60                  


Arg Leu Gly Tyr Tyr Pro Trp Tyr Thr Ser Gln Gly Val Pro Ile Asn 
65                  70                  75                  80  


Gly Gly Leu Pro Gln Asn Ile Ser Leu Gln Val His Leu Glu Lys Ala 
                85                  90                  95      


Asp Gln Asp Ile Asn Tyr Tyr Ile Pro Ala Glu Asp Phe Ser Gly Leu 
            100                 105                 110         


Ala Val Ile Asp Trp Glu Tyr Trp Arg Pro Gln Trp Ala Arg Asn Trp 
        115                 120                 125             


Asn Ser Lys Asp Val Tyr Arg Gln Lys Ser Arg Lys Leu Ile Ser Asp 
    130                 135                 140                 


Met Gly Lys Asn Val Ser Ala Thr Asp Ile Glu Tyr Leu Ala Lys Val 
145                 150                 155                 160 


Thr Phe Glu Glu Ser Ala Lys Ala Phe Met Lys Glu Thr Ile Lys Leu 
                165                 170                 175     


Gly Ile Lys Ser Arg Pro Lys Gly Leu Trp Gly Tyr Tyr Leu Tyr Pro 
            180                 185                 190         


Asp Cys His Asn Tyr Asn Val Tyr Ala Pro Asn Tyr Ser Gly Ser Cys 
        195                 200                 205             


Pro Glu Asp Glu Val Leu Arg Asn Asn Glu Leu Ser Trp Leu Trp Asn 
    210                 215                 220                 


Ser Ser Ala Ala Leu Tyr Pro Ser Ile Gly Val Trp Lys Ser Leu Gly 
225                 230                 235                 240 


Asp Ser Glu Asn Ile Leu Arg Phe Ser Lys Phe Arg Val His Glu Ser 
                245                 250                 255     


Met Arg Ile Ser Thr Met Thr Ser His Asp Tyr Ala Leu Pro Val Phe 
            260                 265                 270         


Val Tyr Thr Arg Leu Gly Tyr Arg Asp Glu Pro Leu Phe Phe Leu Ser 
        275                 280                 285             


Lys Gln Asp Leu Val Ser Thr Ile Gly Glu Ser Ala Ala Leu Gly Ala 
    290                 295                 300                 


Ala Gly Ile Val Ile Trp Gly Asp Met Asn Leu Thr Ser Ser Lys Ala 
305                 310                 315                 320 


Asn Cys Thr Lys Val Lys Gln Phe Val Ser Ser Asp Leu Gly Ser Tyr 
                325                 330                 335     


Ile Ala Asn Val Thr Arg Ala Ala Glu Val Cys Ser Leu His Leu Cys 
            340                 345                 350         


Arg Asn Asn Gly Arg Cys Ile Arg Lys Met Trp Asn Ala Pro Ser Tyr 
        355                 360                 365             


Leu His Leu Asn Pro Ala Ser Tyr His Ile Glu Ala Ser Glu Asp Gly 
    370                 375                 380                 


Glu Phe Thr Val Lys Gly Lys Ala Ser Asp Thr Asp Leu Ala Val Met 
385                 390                 395                 400 


Ala Asp Thr Phe Ser Cys His Cys Tyr Gln Gly Tyr Glu Gly Ala Asp 
                405                 410                 415     


Cys Arg Glu Ile Lys Thr Ala Asp 
            420                 


<210>  2460
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  2460

Ser Arg Gly Ile Lys Gly Lys Arg Gln Arg Arg Ile Ser Ala Glu Gly 
1               5                   10                  15      


Ser Gln Ala Cys Ala Lys Gly Cys Glu Leu Cys Ser Glu Val Asn Gly 
            20                  25                  30          


Cys Leu Lys Cys Ser Pro Lys Leu Phe Ile Leu Leu Glu Arg Asn Asp 
        35                  40                  45              


Ile Arg Gln Val Gly Val Cys Leu Pro Ser Cys Pro Pro Gly Tyr Phe 
    50                  55                  60                  


Asp Ala Arg Asn Pro Asp Met Asn Lys Cys Ile Lys Cys Lys Ile Glu 
65                  70                  75                  80  


His Cys Glu Ala Cys Phe Ser His Asn Phe Cys Thr Lys Cys Lys Glu 
                85                  90                  95      


Gly Leu Tyr Leu His Lys Gly Arg Cys Tyr Pro Ala Cys Pro Glu Gly 
            100                 105                 110         


Ser Ser Ala Ala Asn Gly Thr Met Glu Cys Ser Ser Pro Ala Gln Cys 
        115                 120                 125             


Glu Met Ser Glu Trp Ser Pro Trp Gly Pro Cys Ser Lys Lys Gln Gln 
    130                 135                 140                 


Leu Cys Gly Phe Arg Arg Gly Ser Glu Glu Arg Thr Arg Arg Val Leu 
145                 150                 155                 160 


His Ala Pro Val Gly Asp His Ala Ala Cys Ser Asp Thr Lys Glu Thr 
                165                 170                 175     


Arg Arg Cys Thr Val Arg Arg Val Pro Cys Pro Glu Gly Gln Lys Arg 
            180                 185                 190         


Arg Lys Gly Gly Gln Gly Arg Arg Glu Asn Ala Asn Arg Asn Leu Ala 
        195                 200                 205             


Arg Lys Glu Ser Lys Glu Ala Gly Ala Gly Ser Arg Arg Arg Lys Gly 
    210                 215                 220                 


Gln Gln Gln Gln Gln Gln Gln Gly Thr Val Gly Pro Leu Thr Ser Ala 
225                 230                 235                 240 


Gly Pro Ala 
            


<210>  2461
<211>  565
<212>  PRT
<213>  Homo Sapiens

<400>  2461

Gln Thr Asp Ala Thr Pro Ala Val Thr Thr Glu Gly Leu Asn Ser Thr 
1               5                   10                  15      


Glu Ala Ala Leu Ala Thr Phe Gly Thr Phe Pro Ser Thr Arg Pro Pro 
            20                  25                  30          


Gly Thr Pro Arg Ala Pro Gly Pro Ser Ser Gly Pro Arg Pro Thr Pro 
        35                  40                  45              


Val Thr Asp Val Ala Val Leu Cys Val Cys Asp Leu Ser Pro Ala Gln 
    50                  55                  60                  


Cys Asp Ile Asn Cys Cys Cys Asp Pro Asp Cys Ser Ser Val Asp Phe 
65                  70                  75                  80  


Ser Val Phe Ser Ala Cys Ser Val Pro Val Val Thr Gly Asp Ser Gln 
                85                  90                  95      


Phe Cys Ser Gln Lys Ala Val Ile Tyr Ser Leu Asn Phe Thr Ala Asn 
            100                 105                 110         


Pro Pro Gln Arg Val Phe Glu Leu Val Asp Gln Ile Asn Pro Ser Ile 
        115                 120                 125             


Phe Cys Ile His Ile Thr Asn Tyr Lys Pro Ala Leu Ser Phe Ile Asn 
    130                 135                 140                 


Pro Glu Val Pro Asp Glu Asn Asn Phe Asp Thr Leu Met Lys Thr Ser 
145                 150                 155                 160 


Asp Gly Phe Thr Leu Asn Ala Glu Ser Tyr Val Ser Phe Thr Thr Lys 
                165                 170                 175     


Leu Asp Ile Pro Thr Ala Ala Lys Tyr Glu Tyr Gly Val Pro Leu Gln 
            180                 185                 190         


Thr Ser Asp Ser Phe Leu Arg Phe Pro Ser Ser Leu Thr Ser Ser Leu 
        195                 200                 205             


Cys Thr Asp Asn Asn Pro Ala Ala Phe Leu Val Asn Gln Ala Val Lys 
    210                 215                 220                 


Cys Thr Arg Lys Ile Asn Leu Glu Gln Cys Glu Glu Ile Glu Ala Leu 
225                 230                 235                 240 


Ser Met Ala Phe Tyr Ser Ser Pro Glu Ile Leu Arg Val Pro Asp Ser 
                245                 250                 255     


Arg Lys Lys Val Pro Ile Thr Val Gln Ser Ile Val Ile Gln Ser Leu 
            260                 265                 270         


Asn Lys Thr Leu Thr Arg Arg Glu Asp Thr Asp Val Leu Gln Pro Thr 
        275                 280                 285             


Leu Val Asn Ala Gly His Phe Ser Leu Cys Val Asn Val Val Leu Glu 
    290                 295                 300                 


Val Lys Tyr Ser Leu Thr Tyr Thr Asp Ala Gly Glu Val Thr Lys Ala 
305                 310                 315                 320 


Asp Leu Ser Phe Val Leu Gly Thr Val Ser Ser Val Val Val Pro Leu 
                325                 330                 335     


Gln Gln Lys Phe Glu Ile His Phe Leu Gln Glu Asn Thr Gln Pro Val 
            340                 345                 350         


Pro Leu Ser Gly Asn Pro Gly Tyr Val Val Gly Leu Pro Leu Ala Ala 
        355                 360                 365             


Gly Phe Gln Pro His Lys Gly Ser Gly Ile Ile Gln Thr Thr Asn Arg 
    370                 375                 380                 


Tyr Gly Gln Leu Thr Ile Leu His Ser Thr Thr Glu Gln Asp Cys Leu 
385                 390                 395                 400 


Ala Leu Glu Gly Val Arg Thr Pro Val Leu Phe Gly Tyr Thr Met Gln 
                405                 410                 415     


Ser Gly Cys Lys Leu Arg Leu Thr Gly Ala Leu Pro Cys Gln Leu Val 
            420                 425                 430         


Ala Gln Lys Val Lys Ser Leu Leu Trp Gly Gln Gly Phe Pro Asp Tyr 
        435                 440                 445             


Val Ala Pro Phe Gly Asn Ser Gln Ala Gln Asp Met Leu Asp Trp Val 
    450                 455                 460                 


Pro Ile His Phe Ile Thr Gln Ser Phe Asn Arg Lys Asp Ser Cys Gln 
465                 470                 475                 480 


Leu Pro Gly Ala Leu Val Ile Glu Val Lys Trp Thr Lys Tyr Gly Ser 
                485                 490                 495     


Leu Leu Asn Pro Gln Ala Lys Ile Val Asn Val Thr Ala Asn Leu Ile 
            500                 505                 510         


Ser Ser Ser Phe Pro Glu Ala Asn Ser Gly Asn Glu Arg Thr Ile Leu 
        515                 520                 525             


Ile Ser Thr Ala Val Thr Phe Val Asp Val Ser Ala Pro Ala Glu Ala 
    530                 535                 540                 


Gly Phe Arg Ala Pro Pro Ala Ile Asn Ala Arg Leu Pro Phe Asn Phe 
545                 550                 555                 560 


Phe Phe Pro Phe Val 
                565 


<210>  2462
<211>  298
<212>  PRT
<213>  Homo Sapiens

<400>  2462

Ser Pro Ser Ile Pro Leu Glu Lys Leu Ala Gln Ala Pro Glu Gln Pro 
1               5                   10                  15      


Gly Gln Glu Lys Arg Glu His Ala Ser Arg Asp Gly Pro Gly Arg Val 
            20                  25                  30          


Asn Glu Leu Gly Arg Pro Ala Arg Asp Glu Gly Gly Ser Gly Arg Asp 
        35                  40                  45              


Trp Lys Ser Lys Ser Gly Arg Gly Leu Ala Gly Arg Glu Pro Trp Ser 
    50                  55                  60                  


Lys Leu Lys Gln Ala Trp Val Ser Gln Gly Gly Gly Ala Lys Ala Gly 
65                  70                  75                  80  


Asp Leu Gln Val Arg Pro Arg Gly Asp Thr Pro Gln Ala Glu Ala Leu 
                85                  90                  95      


Ala Ala Ala Ala Gln Asp Ala Ile Gly Pro Glu Leu Ala Pro Thr Pro 
            100                 105                 110         


Glu Pro Pro Glu Glu Tyr Val Tyr Pro Asp Tyr Arg Gly Lys Gly Cys 
        115                 120                 125             


Val Asp Glu Ser Gly Phe Val Tyr Ala Ile Gly Glu Lys Phe Ala Pro 
    130                 135                 140                 


Gly Pro Ser Ala Cys Pro Cys Leu Cys Thr Glu Glu Gly Pro Leu Cys 
145                 150                 155                 160 


Ala Gln Pro Glu Cys Pro Arg Leu His Pro Arg Cys Ile His Val Asp 
                165                 170                 175     


Thr Ser Gln Cys Cys Pro Gln Cys Lys Glu Arg Lys Asn Tyr Cys Glu 
            180                 185                 190         


Phe Arg Gly Lys Thr Tyr Gln Thr Leu Glu Glu Phe Val Val Ser Pro 
        195                 200                 205             


Cys Glu Arg Cys Arg Cys Glu Ala Asn Gly Glu Val Leu Cys Thr Val 
    210                 215                 220                 


Ser Ala Cys Pro Gln Thr Glu Cys Val Asp Pro Val Tyr Glu Pro Asp 
225                 230                 235                 240 


Gln Cys Cys Pro Ile Cys Lys Asn Gly Pro Asn Cys Phe Ala Glu Thr 
                245                 250                 255     


Ala Val Ile Pro Ala Gly Arg Glu Val Lys Thr Asp Glu Cys Thr Ile 
            260                 265                 270         


Cys His Cys Thr Tyr Glu Glu Gly Thr Trp Arg Ile Glu Arg Gln Ala 
        275                 280                 285             


Met Cys Thr Arg His Glu Cys Arg Gln Met 
    290                 295             


<210>  2463
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  2463

Gly Asp Thr Arg Pro Arg Phe Leu Gln Gln Asp Lys Tyr Glu Cys His 
1               5                   10                  15      


Phe Phe Asn Gly Thr Glu Arg Val Arg Phe Leu His Arg Asp Ile Tyr 
            20                  25                  30          


Asn Gln Glu Glu Asp Leu Arg Phe Asp Ser Asp Val Gly Glu Tyr Arg 
        35                  40                  45              


Ala Val Thr Glu Leu Gly Arg Pro Asp Ala Glu Tyr Trp Asn Ser Gln 
    50                  55                  60                  


Lys Asp Phe Leu Glu Asp Arg Arg Ala Ala Val Asp Thr Tyr Cys Arg 
65                  70                  75                  80  


His Asn Tyr Gly Val Gly Glu Ser Phe Thr Val Gln Arg Arg Val Glu 
                85                  90                  95      


Pro Lys Val Thr Val Tyr Pro Ala Arg Thr Gln Thr Leu Gln His His 
            100                 105                 110         


Asn Leu Leu Val Cys Ser Val Asn Gly Phe Tyr Pro Gly Ser Ile Glu 
        115                 120                 125             


Val Arg Trp Phe Arg Asn Ser Gln Glu Glu Lys Ala Gly Val Val Ser 
    130                 135                 140                 


Thr Gly Leu Ile Gln Asn Gly Asp Trp Thr Phe Gln Thr Leu Val Met 
145                 150                 155                 160 


Leu Glu Thr Val Pro Arg Ser Gly Glu Val Tyr Thr Cys Gln Val Glu 
                165                 170                 175     


His Pro Ser Val Thr Ser Pro Leu Thr Val Glu Trp Arg Ala Gln Ser 
            180                 185                 190         


Glu Ser Ala Gln Ser Lys 
        195             


<210>  2464
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2464

Met Phe Gly Asn Asp Gly Val Lys Val Arg Thr Cys Thr Ser Gln Lys 
1               5                   10                  15      


Ala Val Cys Phe Phe Gly Cys Pro Pro Gly Tyr Arg Trp Ile Ala Phe 
            20                  25                  30          


Cys His Asn Ile Leu Ser Cys Cys Lys Asn Met Thr Arg Phe Gln Pro 
        35                  40                  45              


Pro Gln Ala Lys Asp Pro Trp Val His 
    50                  55          


<210>  2465
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2465

Gly Pro Asn Val Tyr Ile Gln Lys Ile Phe Ala Ser Cys Trp Arg Leu 
1               5                   10                  15      


Gln Gly Thr Cys Arg Pro Lys Cys Leu Lys Asn Glu Gln Tyr Arg Ile 
            20                  25                  30          


Leu Cys Asp Thr Ile His Leu Cys Cys Val Asn Pro Lys Tyr Leu Pro 
        35                  40                  45              


Ile Leu Thr Gly Lys 
    50              


<210>  2466
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  2466

Gly Leu Phe Arg Ser His Asn Gly Lys Ser Arg Glu Pro Trp Asn Pro 
1               5                   10                  15      


Cys Glu Leu Tyr Gln Gly Met Cys Arg Asn Ala Cys Arg Glu Tyr Glu 
            20                  25                  30          


Ile Gln Tyr Leu Thr Cys Pro Asn Asp Gln Lys Cys Cys Leu Lys Leu 
        35                  40                  45              


Ser Val Lys Ile Thr Ser Ser Lys Asn Val Lys Glu Asp Tyr Asp Ser 
    50                  55                  60                  


Asn Ser Asn Leu Ser Val Thr Asn Ser Ser Ser Tyr Ser His Ile 
65                  70                  75                  


<210>  2467
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  2467

Gln Thr Ala Pro Asp Gly Trp Ile Arg Arg Cys Tyr Tyr Gly Thr Gly 
1               5                   10                  15      


Arg Cys Arg Lys Ser Cys Lys Glu Ile Glu Arg Lys Lys Glu Lys Cys 
            20                  25                  30          


Gly Glu Lys His Ile Cys Cys Val Pro Lys Glu Lys Asp Lys Leu Ser 
        35                  40                  45              


His Ile His Asp Gln Lys Glu Thr Ser Glu Leu Tyr Ile 
    50                  55                  60      


<210>  2468
<211>  66
<212>  PRT
<213>  Homo Sapiens

<400>  2468

Gly Pro Ser Val Pro Gln Lys Lys Thr Arg Glu Val Ala Glu Arg Lys 
1               5                   10                  15      


Arg Glu Cys Gln Leu Val Arg Gly Ala Cys Lys Pro Glu Cys Asn Ser 
            20                  25                  30          


Trp Glu Tyr Val Tyr Tyr Tyr Cys Asn Val Asn Pro Cys Cys Ala Val 
        35                  40                  45              


Trp Glu Tyr Gln Lys Pro Ile Ile Asn Lys Ile Thr Ser Lys Leu His 
    50                  55                  60                  


Gln Lys 
65      


<210>  2469
<211>  113
<212>  PRT
<213>  Homo Sapiens

<400>  2469

Met Lys Leu Leu Thr Thr Ile Cys Arg Leu Lys Leu Glu Lys Met Tyr 
1               5                   10                  15      


Ser Lys Thr Asn Thr Ser Ser Thr Ile Phe Glu Lys Ala Arg His Gly 
            20                  25                  30          


Thr Glu Lys Ile Ser Thr Ala Arg Ser Glu Gly His His Ile Thr Phe 
        35                  40                  45              


Ser Arg Trp Lys Ser Cys Thr Ala Ile Gly Gly Arg Cys Lys Asn Gln 
    50                  55                  60                  


Cys Asp Asp Ser Glu Phe Arg Ile Ser Tyr Cys Ala Arg Pro Thr Thr 
65                  70                  75                  80  


His Cys Cys Val Thr Glu Cys Asp Pro Thr Asp Pro Asn Asn Trp Ile 
                85                  90                  95      


Pro Lys Asp Ser Val Gly Thr Gln Glu Trp Tyr Pro Lys Asp Ser Arg 
            100                 105                 110         


His 
    


<210>  2470
<211>  352
<212>  PRT
<213>  Homo Sapiens

<400>  2470

Met Glu Ala Ser Ser Ser Gly Ile Thr Asn Gly Lys Thr Lys Val Phe 
1               5                   10                  15      


His Pro Glu Gly Gly Val Asp Leu Gln Gly Tyr Gln Leu Asp Met Gln 
            20                  25                  30          


Ile Leu Pro Asp Gly Pro Lys Ser Asp Val Asp Phe Ser Glu Ile Leu 
        35                  40                  45              


Asn Ala Ile Gln Glu Met Ala Lys Asp Val Asn Ile Leu Phe Asp Glu 
    50                  55                  60                  


Leu Glu Ala Val Ser Ser Pro Cys Lys Asp Asp Asp Ser Leu Leu His 
65                  70                  75                  80  


Pro Gly Asn Leu Thr Ser Thr Ser Asp Asp Ala Ser Arg Leu Glu Ala 
                85                  90                  95      


Gly Gly Glu Thr Val Pro Glu Arg Asn Lys Ser Asn Gly Leu Tyr Phe 
            100                 105                 110         


Arg Asp Gly Lys Cys Arg Ile Asp Tyr Ile Leu Val Tyr Arg Lys Ser 
        115                 120                 125             


Asn Pro Gln Thr Glu Lys Arg Glu Val Phe Glu Arg Asn Ile Arg Ala 
    130                 135                 140                 


Glu Gly Leu Gln Met Glu Lys Glu Ser Ser Leu Ile Asn Ser Asp Ile 
145                 150                 155                 160 


Ile Phe Val Lys Leu His Ala Pro Trp Glu Val Leu Gly Arg Tyr Ala 
                165                 170                 175     


Glu Gln Met Asn Val Arg Met Pro Phe Arg Arg Lys Ile Tyr Tyr Leu 
            180                 185                 190         


Pro Arg Arg Tyr Lys Phe Met Ser Arg Ile Asp Lys Gln Ile Ser Arg 
        195                 200                 205             


Phe Arg Arg Trp Leu Pro Lys Lys Pro Met Arg Leu Asp Lys Glu Thr 
    210                 215                 220                 


Leu Pro Asp Leu Glu Glu Asn Asp Cys Tyr Thr Ala Pro Phe Ser Gln 
225                 230                 235                 240 


Gln Arg Ile His His Phe Ile Ile His Asn Lys Glu Thr Phe Phe Asn 
                245                 250                 255     


Asn Ala Thr Arg Ser Arg Ile Val His His Ile Leu Gln Arg Ile Lys 
            260                 265                 270         


Tyr Glu Glu Gly Lys Asn Lys Ile Gly Leu Asn Arg Leu Leu Thr Asn 
        275                 280                 285             


Gly Ser Tyr Glu Ala Ala Phe Pro Leu His Glu Gly Ser Tyr Arg Ser 
    290                 295                 300                 


Lys Asn Ser Ile Arg Thr His Gly Ala Glu Asn His Arg His Leu Leu 
305                 310                 315                 320 


Tyr Glu Cys Trp Ala Ser Trp Gly Val Trp Tyr Lys Tyr Gln Pro Leu 
                325                 330                 335     


Asp Leu Val Arg Arg Tyr Phe Gly Glu Lys Ile Gly Leu Tyr Phe Ala 
            340                 345                 350         


<210>  2471
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  2471

Cys Val Phe Cys Arg Leu Pro Ala His Asp Leu Ser Gly Arg Leu Ala 
1               5                   10                  15      


Arg Leu Cys Ser Gln Met Glu Ala Arg Gln Lys Glu Cys Gly Ala Ser 
            20                  25                  30          


Pro Asp Phe Ser Ala Phe Ala Leu Asp Glu Val Ser Met Asn Lys Val 
        35                  40                  45              


Thr Glu Lys Thr His Arg Val Leu Arg Val Met Glu Ile Lys Glu Ala 
    50                  55                  60                  


Val Ser Ser Leu Pro Ser Tyr Trp Ser Trp Leu Arg Lys Thr Lys Leu 
65                  70                  75                  80  


Pro Glu Tyr Thr Arg Glu Ala Leu Cys Pro Pro Ala Cys Arg Gly Ser 
                85                  90                  95      


Thr Thr Leu Tyr Asn Cys Ser Thr Cys Lys Gly Thr Glu Val Ser Cys 
            100                 105                 110         


Trp Pro Arg Lys Arg Cys Phe Pro Gly Ser Gln Asp Leu Trp Glu Ala 
        115                 120                 125             


Lys 
    


<210>  2472
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  2472

Ala His Phe Arg Val Cys Glu Pro Tyr Thr Asp His Lys Gly Arg Tyr 
1               5                   10                  15      


His Phe Gly Phe His Cys Pro Arg Leu Ser Asp Asn Lys Thr Phe Ile 
            20                  25                  30          


Leu Cys Cys His His Asn Asn Thr Val Phe Lys Tyr Cys Cys Asn Glu 
        35                  40                  45              


Thr Glu Phe Gln Ala Val Met Gln Ala Asn Leu Thr Ala Ser Ser Glu 
    50                  55                  60                  


Gly Tyr Met His Asn Asn Tyr Thr 
65                  70          


<210>  2473
<211>  461
<212>  PRT
<213>  Homo Sapiens

<400>  2473

Ala Lys Ile Leu Thr Ile Ser Thr Val Gly Gly Ser His Tyr Leu Leu 
1               5                   10                  15      


Met Asp Arg Val Ser Gln Ile Leu Gln Asp His Gly His Asn Val Thr 
            20                  25                  30          


Met Leu Asn His Lys Arg Gly Pro Phe Met Pro Asp Phe Lys Lys Glu 
        35                  40                  45              


Glu Lys Ser Tyr Gln Val Ile Ser Trp Leu Ala Pro Glu Asp His Gln 
    50                  55                  60                  


Arg Glu Phe Lys Lys Ser Phe Asp Phe Phe Leu Glu Glu Thr Leu Gly 
65                  70                  75                  80  


Gly Arg Gly Lys Phe Glu Asn Leu Leu Asn Val Leu Glu Tyr Leu Ala 
                85                  90                  95      


Leu Gln Cys Ser His Phe Leu Asn Arg Lys Asp Ile Met Asp Ser Leu 
            100                 105                 110         


Lys Asn Glu Asn Phe Asp Met Val Ile Val Glu Thr Phe Asp Tyr Cys 
        115                 120                 125             


Pro Phe Leu Ile Ala Glu Lys Leu Gly Lys Pro Phe Val Ala Ile Leu 
    130                 135                 140                 


Ser Thr Ser Phe Gly Ser Leu Glu Phe Gly Leu Pro Ile Pro Leu Ser 
145                 150                 155                 160 


Tyr Val Pro Val Phe Arg Ser Leu Leu Thr Asp His Met Asp Phe Trp 
                165                 170                 175     


Gly Arg Val Lys Asn Phe Leu Met Phe Phe Ser Phe Cys Arg Arg Gln 
            180                 185                 190         


Gln His Met Gln Ser Thr Phe Asp Asn Thr Ile Lys Glu His Phe Thr 
        195                 200                 205             


Glu Gly Ser Arg Pro Val Leu Ser His Leu Leu Leu Lys Ala Glu Leu 
    210                 215                 220                 


Trp Phe Ile Asn Ser Asp Phe Ala Phe Asp Phe Ala Arg Pro Leu Leu 
225                 230                 235                 240 


Pro Asn Thr Val Tyr Val Gly Gly Leu Met Glu Lys Pro Ile Lys Pro 
                245                 250                 255     


Val Pro Gln Asp Leu Glu Asn Phe Ile Ala Lys Phe Gly Asp Ser Gly 
            260                 265                 270         


Phe Val Leu Val Thr Leu Gly Ser Met Val Asn Thr Cys Gln Asn Pro 
        275                 280                 285             


Glu Ile Phe Lys Glu Met Asn Asn Ala Phe Ala His Leu Pro Gln Gly 
    290                 295                 300                 


Val Ile Trp Lys Cys Gln Cys Ser His Trp Pro Lys Asp Val His Leu 
305                 310                 315                 320 


Ala Ala Asn Val Lys Ile Val Asp Trp Leu Pro Gln Ser Asp Leu Leu 
                325                 330                 335     


Ala His Pro Ser Ile Arg Leu Phe Val Thr His Gly Gly Gln Asn Ser 
            340                 345                 350         


Ile Met Glu Ala Ile Gln His Gly Val Pro Met Val Gly Ile Pro Leu 
        355                 360                 365             


Phe Gly Asp Gln Pro Glu Asn Met Val Arg Val Glu Ala Lys Lys Phe 
    370                 375                 380                 


Gly Val Ser Ile Gln Leu Lys Lys Leu Lys Ala Glu Thr Leu Ala Leu 
385                 390                 395                 400 


Lys Met Lys Gln Ile Met Glu Asp Lys Arg Tyr Lys Ser Ala Ala Val 
                405                 410                 415     


Ala Ala Ser Val Ile Leu Arg Ser His Pro Leu Ser Pro Thr Gln Arg 
            420                 425                 430         


Leu Val Gly Trp Ile Asp His Val Leu Gln Thr Gly Gly Ala Thr His 
        435                 440                 445             


Leu Lys Pro Tyr Val Phe Gln Gln Pro Trp His Glu Gln 
    450                 455                 460     


<210>  2474
<211>  208
<212>  PRT
<213>  Homo Sapiens

<400>  2474

Gly Phe Gln Gly Thr Ala Ala Ile Trp Pro Ser Leu Phe Asn Val Asn 
1               5                   10                  15      


Leu Ser Lys Lys Val Gln Glu Ser Ile Gln Ile Pro Asn Asn Gly Ser 
            20                  25                  30          


Ala Pro Leu Leu Val Asp Val Arg Val Phe Val Ser Asn Val Phe Asn 
        35                  40                  45              


Val Asp Ile Leu Arg Tyr Thr Met Ser Ser Met Leu Leu Leu Arg Leu 
    50                  55                  60                  


Ser Trp Leu Asp Thr Arg Leu Ala Trp Asn Thr Ser Ala His Pro Arg 
65                  70                  75                  80  


His Ala Ile Thr Leu Pro Trp Glu Ser Leu Trp Thr Pro Arg Leu Thr 
                85                  90                  95      


Ile Leu Glu Ala Leu Trp Val Asp Trp Arg Asp Gln Ser Pro Gln Ala 
            100                 105                 110         


Arg Val Asp Gln Asp Gly His Val Lys Leu Asn Leu Ala Leu Thr Thr 
        115                 120                 125             


Glu Thr Asn Cys Asn Phe Glu Leu Leu His Phe Pro Arg Asp His Ser 
    130                 135                 140                 


Asn Cys Ser Leu Ser Phe Tyr Ala Leu Ser Asn Thr Ala Met Glu Leu 
145                 150                 155                 160 


Glu Phe Gln Ala His Val Val Asn Glu Ile Val Ser Val Lys Arg Glu 
                165                 170                 175     


Tyr Val Val Tyr Asp Leu Lys Thr Gln Val Pro Pro Gln Gln Leu Val 
            180                 185                 190         


Pro Cys Phe Gln Val Thr Leu Arg Leu Lys Asn Thr Ala Leu Lys Ser 
        195                 200                 205             


<210>  2475
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  2475

Ala Ala Gly Pro Asn Arg Cys Asp Thr Ile Tyr Gln Gly Phe Ala Glu 
1               5                   10                  15      


Cys Leu Ile Arg Leu Gly Asp Ser Met Gly Arg Gly Gly Glu Leu Glu 
            20                  25                  30          


Thr Ile Cys Arg Ser Trp Asn Asp Phe His Ala Cys Ala Ser Gln Val 
        35                  40                  45              


Leu Ser Gly Cys Pro Glu Glu Ala Ala Ala Val Trp Glu Ser Leu Gln 
    50                  55                  60                  


Gln Glu Ala Arg Gln Ala Pro Arg Pro Asn Asn Leu His Thr Leu Cys 
65                  70                  75                  80  


Gly Ala Pro Val His Val Arg Glu Arg Gly Thr Gly Ser Glu Thr Asn 
                85                  90                  95      


Gln Glu Thr Leu Arg Ala Thr Ala 
            100                 


<210>  2476
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  2476

Lys Pro Leu Gln Ser Asp Glu Tyr Ala Leu Leu Thr Arg Asn Val Glu 
1               5                   10                  15      


Arg Asp Lys Tyr Ala Asn Phe Thr Ile Asn Phe Thr Met Glu Asn Gln 
            20                  25                  30          


Ile His Thr Gly Met Glu Tyr Asp Asn Gly Arg Phe Ile Gly Val Lys 
        35                  40                  45              


Phe Lys Ser Val Thr Phe Lys Asp Ser Val Phe Lys Ser Cys Thr Phe 
    50                  55                  60                  


Glu Asp Val Thr Ser Val Asn Thr Tyr Phe Lys Asn Cys Thr Phe Ile 
65                  70                  75                  80  


Asp Thr Val Phe Asp Asn Thr Asp Phe Glu Pro Tyr Lys Phe Ile Asp 
                85                  90                  95      


Ser Glu Phe Lys Asn Cys Ser Phe Phe His Asn Lys Thr Gly Cys Gln 
            100                 105                 110         


Ile Thr Phe Asp Asp Asp Tyr Ser 
        115                 120 


<210>  2477
<211>  163
<212>  PRT
<213>  Homo Sapiens

<400>  2477

Gln Gly Gln Glu Ala Gly Gly Arg Pro Gly Ala Asp Cys Glu Val Cys 
1               5                   10                  15      


Lys Glu Phe Leu Asn Arg Phe Tyr Lys Ser Leu Ile Asp Arg Gly Val 
            20                  25                  30          


Asn Phe Ser Leu Asp Thr Ile Glu Lys Glu Leu Ile Ser Phe Cys Leu 
        35                  40                  45              


Asp Thr Lys Gly Lys Glu Asn Arg Leu Cys Tyr Tyr Leu Gly Ala Thr 
    50                  55                  60                  


Lys Asp Ala Ala Thr Lys Ile Leu Ser Glu Val Thr Arg Pro Met Ser 
65                  70                  75                  80  


Val His Met Pro Ala Met Lys Ile Cys Glu Lys Leu Lys Lys Leu Asp 
                85                  90                  95      


Ser Gln Ile Cys Glu Leu Lys Tyr Glu Lys Thr Leu Asp Leu Ala Ser 
            100                 105                 110         


Val Asp Leu Arg Lys Met Arg Val Ala Glu Leu Lys Gln Ile Leu His 
        115                 120                 125             


Ser Trp Gly Glu Glu Cys Arg Ala Cys Ala Glu Lys Thr Asp Tyr Val 
    130                 135                 140                 


Asn Leu Ile Gln Glu Leu Ala Pro Lys Tyr Ala Ala Thr His Pro Lys 
145                 150                 155                 160 


Thr Glu Leu 
            


<210>  2478
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  2478

Cys Leu Asp Ile Asp Lys Leu Leu Ala Asn Val Val Phe Asp Val Ser 
1               5                   10                  15      


Gln Asp Leu Leu Lys Glu Glu Leu Ala Arg Tyr Asn Pro Ser Pro Leu 
            20                  25                  30          


Thr Glu Glu Ser Phe Leu Asn Val Gln Gln Cys Phe Ala Asn Val Ser 
        35                  40                  45              


Val Thr Glu Arg Phe Ala His Ser Val Val Ile Lys Lys Ile Leu Gln 
    50                  55                  60                  


Ser Asn Asp Cys Ile Glu Ala Ala Phe 
65                  70              


<210>  2479
<211>  97
<212>  PRT
<213>  Homo Sapiens

<400>  2479

Lys Gly Lys Phe Val Gly Tyr Pro Gly Asp Pro Val Tyr Trp Leu Gly 
1               5                   10                  15      


Lys Tyr Arg Asn Glu Glu Cys Asp Pro Gly Gly Cys Leu Leu Glu Leu 
            20                  25                  30          


Thr Thr Gln Leu Thr Ile Ile Met Gly Gly Lys Ala Ile Trp Asn Asn 
        35                  40                  45              


Ile Gln Glu Val Leu Leu Pro Trp Ile Met Asn Leu Ile Gly Arg Phe 
    50                  55                  60                  


His Arg Val Ser Gly Ser Glu Lys Ile Thr Pro Arg Trp Glu Gln Asp 
65                  70                  75                  80  


Tyr His Leu Gln Pro Met Gly Lys Leu Gly Leu Phe Tyr Glu Tyr Leu 
                85                  90                  95      


Glu 
    


<210>  2480
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  2480

Met Ala Ser His Asn Thr Leu Gln Asn Phe Thr Ala Ala Ile Pro Thr 
1               5                   10                  15      


His His Cys Arg Pro Pro Ala Asp Ala Asn Leu Ser Lys Asn Gly Gly 
            20                  25                  30          


Leu Glu Val Trp Leu Pro Arg Asp Arg Gln Gly Gln Pro Glu Ser Cys 
        35                  40                  45              


Leu Arg Phe Thr Ser Pro Gln Trp Gly Leu Pro Phe Leu Asn Gly Thr 
    50                  55                  60                  


Glu Ala Asn Gly Thr Gly Ala Thr Glu Pro Cys Thr Asp Gly Trp Ile 
65                  70                  75                  80  


Tyr Asp Asn Ser Thr Phe Pro Ser Thr Ile Val Thr Glu Trp Asp Leu 
                85                  90                  95      


Val Cys Ser His Arg Ala Leu Arg Gln 
            100                 105 


<210>  2481
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  2481

Glu Leu Met Pro Ser Gly Ala Ile Leu Gln Asn Lys Arg Glu Asn Leu 
1               5                   10                  15      


Pro Arg Val Cys His Ala Leu Ala Phe Leu Gly Met Ala Arg Cys Gln 
            20                  25                  30          


Asp Leu Phe Leu Val Arg Leu Gln Gly Trp Lys Leu Gly Thr Arg Phe 
        35                  40                  45              


Gln Asp Gly Pro Arg Ser Thr Pro Gln Glu Glu Gly Gly Ser Pro Gln 
    50                  55                  60                  


Arg Lys Arg Gly Met Pro Val Gln Ile His Phe Leu Leu Lys Ser Phe 
65                  70                  75                  80  


Leu Ser Ser Pro Ile Thr Phe Ala Phe Ile Ser Leu Ala Arg Thr Val 
                85                  90                  95      


Ser Leu Ala Thr Ala Ile Cys Lys Ile Val 
            100                 105     


<210>  2482
<211>  202
<212>  PRT
<213>  Homo Sapiens

<400>  2482

Met Cys Phe Arg Thr Lys Leu Ser Val Ser Trp Val Pro Leu Phe Leu 
1               5                   10                  15      


Leu Leu Ser Arg Val Phe Ser Thr Glu Thr Asp Lys Pro Ser Ala Gln 
            20                  25                  30          


Asp Ser Arg Ser Arg Gly Ser Ser Gly Gln Pro Ala Asp Leu Leu Gln 
        35                  40                  45              


Val Leu Ser Ala Gly Asp His Pro Pro His Asn His Ser Arg Ser Leu 
    50                  55                  60                  


Ile Lys Thr Leu Leu Glu Lys Thr Gly Cys Pro Arg Arg Arg Asn Gly 
65                  70                  75                  80  


Met Gln Gly Asp Cys Asn Leu Cys Phe Glu Pro Asp Ala Leu Leu Leu 
                85                  90                  95      


Ile Ala Gly Gly Asn Phe Glu Asp Gln Leu Arg Glu Glu Val Val Gln 
            100                 105                 110         


Arg Val Ser Leu Leu Leu Leu Tyr Tyr Ile Ile His Gln Glu Glu Ile 
        115                 120                 125             


Cys Ser Ser Lys Leu Asn Met Ser Asn Lys Glu Tyr Lys Phe Tyr Leu 
    130                 135                 140                 


His Ser Leu Leu Ser Leu Arg Gln Asp Glu Asp Ser Ser Phe Leu Ser 
145                 150                 155                 160 


Gln Asn Glu Thr Glu Asp Ile Leu Ala Phe Thr Arg Gln Tyr Phe Asp 
                165                 170                 175     


Thr Ser Gln Ser Gln Cys Met Glu Thr Lys Thr Leu Gln Lys Lys Ser 
            180                 185                 190         


Gly Ile Val Ser Ser Glu Gly Ala Asn Glu 
        195                 200         


<210>  2483
<211>  906
<212>  PRT
<213>  Homo Sapiens

<400>  2483

Leu Ser Leu Glu Ala Pro Thr Val Gly Lys Gly Gln Ala Pro Gly Ile 
1               5                   10                  15      


Glu Glu Thr Asp Gly Glu Leu Thr Ala Ala Pro Thr Pro Glu Gln Pro 
            20                  25                  30          


Glu Arg Gly Val His Phe Val Thr Thr Ala Pro Thr Leu Lys Leu Leu 
        35                  40                  45              


Asn His His Pro Leu Leu Glu Glu Phe Leu Gln Glu Gly Leu Glu Lys 
    50                  55                  60                  


Gly Asp Glu Glu Leu Arg Pro Ala Leu Pro Phe Gln Pro Asp Pro Pro 
65                  70                  75                  80  


Ala Pro Phe Thr Pro Ser Pro Leu Pro Arg Leu Ala Asn Gln Asp Ser 
                85                  90                  95      


Arg Pro Val Phe Thr Ser Pro Thr Pro Ala Met Ala Ala Val Pro Thr 
            100                 105                 110         


Gln Pro Gln Ser Lys Glu Gly Pro Trp Ser Pro Glu Ser Glu Ser Pro 
        115                 120                 125             


Met Leu Arg Ile Thr Ala Pro Leu Pro Pro Gly Pro Ser Met Ala Val 
    130                 135                 140                 


Pro Thr Leu Gly Pro Gly Glu Ile Ala Ser Thr Thr Pro Pro Ser Arg 
145                 150                 155                 160 


Ala Trp Thr Pro Thr Gln Glu Gly Pro Gly Asp Met Gly Arg Pro Trp 
                165                 170                 175     


Val Ala Glu Val Val Ser Gln Gly Ala Gly Ile Gly Ile Gln Gly Thr 
            180                 185                 190         


Ile Thr Ser Ser Thr Ala Ser Gly Asp Asp Glu Glu Thr Thr Thr Thr 
        195                 200                 205             


Thr Thr Ile Ile Thr Thr Thr Ile Thr Thr Val Gln Thr Pro Gly Pro 
    210                 215                 220                 


Cys Ser Trp Asn Phe Ser Gly Pro Glu Gly Ser Leu Asp Ser Pro Thr 
225                 230                 235                 240 


Asp Leu Ser Ser Pro Thr Asp Val Gly Leu Asp Cys Phe Phe Tyr Ile 
                245                 250                 255     


Ser Val Tyr Pro Gly Tyr Gly Val Glu Ile Lys Val Gln Asn Ile Ser 
            260                 265                 270         


Leu Arg Glu Gly Glu Thr Val Thr Val Glu Gly Leu Gly Gly Pro Asp 
        275                 280                 285             


Pro Leu Pro Leu Ala Asn Gln Ser Phe Leu Leu Arg Gly Gln Val Ile 
    290                 295                 300                 


Arg Ser Pro Thr His Gln Ala Ala Leu Arg Phe Gln Ser Leu Pro Pro 
305                 310                 315                 320 


Pro Ala Gly Pro Gly Thr Phe His Phe His Tyr Gln Ala Tyr Leu Leu 
                325                 330                 335     


Ser Cys His Phe Pro Arg Arg Pro Ala Tyr Gly Asp Val Thr Val Thr 
            340                 345                 350         


Ser Leu His Pro Gly Gly Ser Ala Arg Phe His Cys Ala Thr Gly Tyr 
        355                 360                 365             


Gln Leu Lys Gly Ala Arg His Leu Thr Cys Leu Asn Ala Thr Gln Pro 
    370                 375                 380                 


Phe Trp Asp Ser Lys Glu Pro Val Cys Ile Gly Glu Cys Pro Gly Val 
385                 390                 395                 400 


Ile Arg Asn Ala Thr Thr Gly Arg Ile Val Ser Pro Gly Phe Pro Gly 
                405                 410                 415     


Asn Tyr Ser Asn Asn Leu Thr Cys His Trp Leu Leu Glu Ala Pro Glu 
            420                 425                 430         


Gly Gln Arg Leu His Leu His Phe Glu Lys Val Ser Leu Ala Glu Asp 
        435                 440                 445             


Asp Asp Arg Leu Ile Ile Arg Asn Gly Asp Asn Val Glu Ala Pro Pro 
    450                 455                 460                 


Val Tyr Asp Ser Tyr Glu Val Glu Tyr Leu Pro Ile Glu Gly Leu Leu 
465                 470                 475                 480 


Ser Ser Gly Lys His Phe Phe Val Glu Leu Ser Thr Asp Ser Ser Gly 
                485                 490                 495     


Ala Ala Ala Gly Met Ala Leu Arg Tyr Glu Ala Phe Gln Gln Gly His 
            500                 505                 510         


Cys Tyr Glu Pro Phe Val Lys Tyr Gly Asn Phe Ser Ser Ser Thr Pro 
        515                 520                 525             


Thr Tyr Pro Val Gly Thr Thr Val Glu Phe Ser Cys Asp Pro Gly Tyr 
    530                 535                 540                 


Thr Leu Glu Gln Gly Ser Ile Ile Ile Glu Cys Val Asp Pro His Asp 
545                 550                 555                 560 


Pro Gln Trp Asn Glu Thr Glu Pro Ala Cys Arg Ala Val Cys Ser Gly 
                565                 570                 575     


Glu Ile Thr Asp Ser Ala Gly Val Val Leu Ser Pro Asn Trp Pro Glu 
            580                 585                 590         


Pro Tyr Gly Arg Gly Gln Asp Cys Ile Trp Gly Val His Val Glu Glu 
        595                 600                 605             


Asp Lys Arg Ile Met Leu Asp Ile Arg Val Leu Arg Ile Gly Pro Gly 
    610                 615                 620                 


Asp Val Leu Thr Phe Tyr Asp Gly Asp Asp Leu Thr Ala Arg Val Leu 
625                 630                 635                 640 


Gly Gln Tyr Ser Gly Pro Arg Ser His Phe Lys Leu Phe Thr Ser Met 
                645                 650                 655     


Ala Asp Val Thr Ile Gln Phe Gln Ser Asp Pro Gly Thr Ser Val Leu 
            660                 665                 670         


Gly Tyr Gln Gln Gly Phe Val Ile His Phe Phe Glu Val Pro Arg Asn 
        675                 680                 685             


Asp Thr Cys Pro Glu Leu Pro Glu Ile Pro Asn Gly Trp Lys Ser Pro 
    690                 695                 700                 


Ser Gln Pro Glu Leu Val His Gly Thr Val Val Thr Tyr Gln Cys Tyr 
705                 710                 715                 720 


Pro Gly Tyr Gln Val Val Gly Ser Ser Val Leu Met Cys Gln Trp Asp 
                725                 730                 735     


Leu Thr Trp Ser Glu Asp Leu Pro Ser Cys Gln Arg Val Thr Ser Cys 
            740                 745                 750         


His Asp Pro Gly Asp Val Glu His Ser Arg Arg Leu Ile Ser Ser Pro 
        755                 760                 765             


Lys Phe Pro Val Gly Ala Thr Val Gln Tyr Ile Cys Asp Gln Gly Phe 
    770                 775                 780                 


Val Leu Met Gly Ser Ser Ile Leu Thr Cys His Asp Arg Gln Ala Gly 
785                 790                 795                 800 


Ser Pro Lys Trp Ser Asp Arg Ala Pro Lys Cys Leu Leu Glu Gln Leu 
                805                 810                 815     


Lys Pro Cys His Gly Leu Ser Ala Pro Glu Asn Gly Ala Arg Ser Pro 
            820                 825                 830         


Glu Lys Gln Leu His Pro Ala Gly Ala Thr Ile His Phe Ser Cys Ala 
        835                 840                 845             


Pro Gly Tyr Val Leu Lys Gly Gln Ala Ser Ile Lys Cys Val Pro Gly 
    850                 855                 860                 


His Pro Ser His Trp Ser Asp Pro Pro Pro Ile Cys Arg Ala Ala Ser 
865                 870                 875                 880 


Leu Asp Gly Phe Tyr Asn Ser Arg Ser Leu Asp Val Ala Lys Ala Pro 
                885                 890                 895     


Ala Ala Ser Ser Thr Leu Asp Ala Ala His 
            900                 905     


<210>  2484
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  2484

Asp Ala Pro Pro Thr Pro Gln Pro Lys Cys Ala Asp Phe Gln Ser Ala 
1               5                   10                  15      


Asn Leu Phe Glu Gly Thr Asp Leu Lys Val Gln Phe Leu Leu Phe Val 
            20                  25                  30          


Pro Ser Asn Pro Ser Cys Gly Gln Leu Val Glu Gly Ser Ser Asp Leu 
        35                  40                  45              


Gln Asn Ser Gly Phe Asn Ala Thr Leu Gly Thr Lys Leu Ile Ile His 
    50                  55                  60                  


Gly Phe Arg Val Leu Gly Thr Lys Pro Ser Trp Ile Asp Thr Phe Ile 
65                  70                  75                  80  


Arg Thr Leu Leu Arg Ala Thr Asn Ala Asn Val Ile Ala Val Asp Trp 
                85                  90                  95      


Ile Tyr Gly Ser Thr Gly Val Tyr Phe Ser Ala Val Lys Asn Val Leu 
            100                 105                 110         


Gly Val Ser Glu Ser Ser Ile His Ile Ile Gly Val Ser Leu Gly Ala 
        115                 120                 125             


His Val Gly Gly Met Val Gly Gln Leu Phe Gly Gly Gln Leu Gly Gln 
    130                 135                 140                 


Ile Thr Gly Leu Asp Pro Ala Gly Pro Glu Tyr Thr Arg Ala Ser Val 
145                 150                 155                 160 


Glu Glu Arg Leu Asp Ala Gly Asp Ala Leu Phe Val Glu Ala Ile His 
                165                 170                 175     


Thr Asp Thr Asp Asn Leu Gly Ile Arg Ile Pro Val Gly His Val Asp 
            180                 185                 190         


Tyr Phe Val Asn Gly Gly Gln Asp Gln Pro Gly Cys Pro Thr Phe Phe 
        195                 200                 205             


Tyr Ala Gly Tyr Ser Tyr Leu Ile Cys Asp His Met Arg Ala Val His 
    210                 215                 220                 


Leu Tyr Ile Ser Ala Leu Glu Asn Ser Cys Pro Leu Met Ala Phe Pro 
225                 230                 235                 240 


Cys Ala Ser Tyr Lys Ala Phe Leu Ala Gly Arg Cys Leu Asp Cys Phe 
                245                 250                 255     


Asn Pro Phe Leu Leu Ser Cys Pro Arg Ile Gly Leu Val Glu Gln Gly 
            260                 265                 270         


Gly Val Lys Ile Glu Pro Leu Pro Lys Glu Val Lys Val Tyr Leu Leu 
        275                 280                 285             


Thr Thr Ser Ser Ala Pro Tyr Cys Met His His Ser Leu Val Glu Phe 
    290                 295                 300                 


His Leu Lys Glu Leu Arg Asn Lys Asp Thr Asn Ile Glu Val Thr Phe 
305                 310                 315                 320 


Leu Ser Ser Asn Ile Thr Ser Ser Ser Lys Ile Thr Ile Pro Lys Gln 
                325                 330                 335     


Gln Arg Tyr Gly Lys Gly Ile Ile Ala His Ala Thr Pro Gln Cys Gln 
            340                 345                 350         


Ile Asn Gln Val Lys Phe Lys Phe Gln Ser Ser Asn Arg Val Trp Lys 
        355                 360                 365             


Lys Asp Arg Thr Thr Ile Ile Gly Lys Phe Cys Thr Ala Leu Leu Pro 
    370                 375                 380                 


Val Asn Asp Arg Glu Lys Met Val Cys Leu Pro Glu Pro Val Asn Leu 
385                 390                 395                 400 


Gln Ala Ser Val Thr Val Ser Cys Asp Leu Lys Ile Ala Cys Val 
                405                 410                 415 


<210>  2485
<211>  267
<212>  PRT
<213>  Homo Sapiens

<400>  2485

Glu Val Pro Glu Glu Ser Ser Arg Met Ala Gly Ser Gly Ala Arg Ser 
1               5                   10                  15      


Glu Glu Gly Arg Arg Gln His Ala Phe Val Pro Glu Pro Phe Asp Gly 
            20                  25                  30          


Ala Asn Val Val Pro Asn Leu Trp Leu His Ser Phe Glu Val Ile Asn 
        35                  40                  45              


Asp Leu Asn His Trp Asp His Ile Thr Lys Leu Arg Phe Leu Lys Glu 
    50                  55                  60                  


Ser Leu Arg Gly Glu Ala Leu Gly Val Tyr Asn Arg Leu Ser Pro Gln 
65                  70                  75                  80  


Asp Gln Gly Asp Tyr Gly Thr Val Lys Glu Ala Leu Leu Lys Ala Phe 
                85                  90                  95      


Gly Val Pro Gly Ala Ala Pro Ser His Leu Pro Lys Glu Ile Val Phe 
            100                 105                 110         


Ala Asn Ser Met Gly Lys Gly Tyr Tyr Leu Lys Gly Lys Ile Gly Lys 
        115                 120                 125             


Val Pro Val Arg Phe Leu Val Asp Ser Gly Ala Gln Val Ser Val Val 
    130                 135                 140                 


His Pro Asn Leu Trp Glu Glu Val Thr Asp Gly Asp Leu Asp Thr Leu 
145                 150                 155                 160 


Gln Pro Phe Glu Asn Val Val Lys Val Ala Asn Gly Ala Glu Met Lys 
                165                 170                 175     


Ile Leu Gly Val Trp Asp Thr Ala Val Ser Leu Gly Lys Leu Lys Leu 
            180                 185                 190         


Lys Ala Gln Phe Leu Val Ala Asn Ala Ser Ala Glu Glu Ala Ile Ile 
        195                 200                 205             


Gly Thr Asp Val Leu Gln Asp His Asn Ala Ile Leu Asp Phe Glu His 
    210                 215                 220                 


Arg Thr Cys Thr Leu Lys Gly Lys Lys Phe Arg Leu Leu Pro Val Gly 
225                 230                 235                 240 


Gly Ser Leu Glu Asp Glu Phe Asp Leu Glu Leu Ile Glu Glu Asp Pro 
                245                 250                 255     


Ser Ser Glu Glu Gly Arg Gln Glu Leu Ser His 
            260                 265         


<210>  2486
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  2486

Ile Glu Cys Ala Lys Gln Thr Lys Gln Met Val Asp Cys Ser His Tyr 
1               5                   10                  15      


Lys Lys Leu Pro Pro Gly Gln Gln Arg Phe Cys His His Met Tyr Asp 
            20                  25                  30          


Pro Ile Cys Gly Ser Asp Gly Lys Thr Tyr Lys Asn Asp Cys Phe Phe 
        35                  40                  45              


Cys Ser Lys Val Lys Lys Thr Asp Gly Thr Leu Lys Phe Val His Phe 
    50                  55                  60                  


Gly Lys Cys 
65          


<210>  2487
<211>  140
<212>  PRT
<213>  Homo Sapiens

<400>  2487

Met Asp Ser Arg Ile Pro Tyr Asp Asp Tyr Pro Val Val Phe Leu Pro 
1               5                   10                  15      


Ala Tyr Glu Asn Pro Pro Ala Trp Ile Pro Pro His Glu Arg Val His 
            20                  25                  30          


His Pro Asp Tyr Asn Asn Glu Leu Thr Gln Phe Leu Pro Arg Thr Ile 
        35                  40                  45              


Thr Leu Lys Lys Pro Pro Gly Ala Gln Leu Gly Phe Asn Ile Arg Gly 
    50                  55                  60                  


Gly Lys Ala Ser Gln Leu Gly Ile Phe Ile Ser Lys Val Ile Pro Asp 
65                  70                  75                  80  


Ser Asp Ala His Arg Ala Gly Leu Gln Glu Gly Asp Gln Val Leu Ala 
                85                  90                  95      


Val Asn Asp Val Asp Phe Gln Asp Ile Glu His Ser Lys Ala Val Glu 
            100                 105                 110         


Ile Leu Lys Thr Ala Arg Glu Ile Ser Met Arg Val Arg Phe Phe Pro 
        115                 120                 125             


Tyr Asn Tyr His Arg Gln Lys Glu Arg Thr Val His 
    130                 135                 140 


<210>  2488
<211>  447
<212>  PRT
<213>  Homo Sapiens

<400>  2488

Arg Gly Phe Pro Arg Pro Leu Glu Asn Ser Glu Ile Pro Met Ile Pro 
1               5                   10                  15      


Gly Ala His Pro Lys Gly Ser Val Gly Ser Glu Pro Gln Ala Phe Asp 
            20                  25                  30          


Val Phe Pro Glu Asn Pro Arg Ala Asp Ser His Arg Asn Ser Asp Val 
        35                  40                  45              


Arg His Ala Pro Ala Glu Glu Met Pro Glu Lys Pro Val Ala Ser Pro 
    50                  55                  60                  


Leu Gly Pro Ala Leu Tyr Gly Pro Lys Ala Ala Gln Gly Ala Gln Arg 
65                  70                  75                  80  


Glu Arg Leu Pro Val Thr Asp Asp Leu Gln Met Ala Gln Gly Pro Ser 
                85                  90                  95      


Ser His Gly Trp Thr Gly Pro Leu Asp Ser Gln Glu Leu Leu Glu Gln 
            100                 105                 110         


Glu Ala Val Ala Pro His Pro Val Gly His Pro His Leu Thr Phe Ile 
        115                 120                 125             


Pro Thr Thr Pro Arg Arg Gln Leu Arg Val Ala Thr Val Pro Pro Ser 
    130                 135                 140                 


Leu Gln His Glu Gly Gln Glu Gly Gln Trp Pro Pro Arg Asp Glu Gly 
145                 150                 155                 160 


Leu Lys Ala Lys Thr Lys Ser Arg Val Pro Pro Thr Ser Pro Ser Asp 
                165                 170                 175     


His Gln Gly Pro Pro His Thr Leu Val Ser His Ser Gly Thr Val Lys 
            180                 185                 190         


Arg Pro Val Leu Glu Gly Gln Gly Gly Phe Glu Glu His Leu Gln Glu 
        195                 200                 205             


Ala Ala Gln Gly Pro His Phe Thr Gln Gln Asp Pro Ala Ala Pro Asp 
    210                 215                 220                 


Val Gly Ser Val Pro Pro Val Glu Val Val Tyr Ser Gln Glu Pro Gly 
225                 230                 235                 240 


Ala Gln Pro Asp Leu Ala Leu Ala Arg Ser Leu Pro Pro Ala Glu Glu 
                245                 250                 255     


Leu Pro Val Glu Thr Pro Lys Arg Ala Gly Ala Glu Val Ser Trp Glu 
            260                 265                 270         


Val Ser Ser Pro Gly Pro Pro Pro Lys Gln Ala Asp Leu Pro Asp Ala 
        275                 280                 285             


Lys Asp Ser Pro Gly Pro Gln Pro Thr Asp Pro Pro Ala Ser Glu Ala 
    290                 295                 300                 


Pro Asp Arg Pro Ser Lys Pro Glu Arg Ala Ala Met Asn Gly Ala Asp 
305                 310                 315                 320 


Pro Ile Ser Pro Gln Arg Val Arg Gly Ala Val Glu Ala Pro Gly Thr 
                325                 330                 335     


Pro Lys Ser Leu Ile Pro Gly Pro Ser Asp Pro Gly Pro Ala Val Asn 
            340                 345                 350         


Arg Thr Glu Ser Pro Met Gly Ala Leu Gln Pro Asp Glu Ala Glu Glu 
        355                 360                 365             


Trp Pro Gly Arg Pro Gln Ser His Pro Pro Ala Pro Pro Val Gln Ala 
    370                 375                 380                 


Pro Ser Thr Ser Arg Arg Gly Leu Ile Arg Val Thr Thr Gln Arg Ala 
385                 390                 395                 400 


Leu Gly Gln Pro Pro Pro Pro Glu Pro Thr Ala Ser Ser Met Ala Ser 
                405                 410                 415     


Ala Pro Ala Ser Ser Pro Pro Ala Asn Ala Thr Ala Pro Pro Leu Arg 
            420                 425                 430         


Trp Gly Pro Leu Arg Arg Val Leu Ser Phe Ser Trp Glu Leu His 
        435                 440                 445         


<210>  2489
<211>  550
<212>  PRT
<213>  Homo Sapiens

<400>  2489

Leu Glu Glu Glu Glu Glu Gly Ala Leu Leu Ala Gln Ala Gly Glu Lys 
1               5                   10                  15      


Leu Glu Pro Ser Thr Thr Ser Thr Ser Gln Pro His Leu Ile Phe Ile 
            20                  25                  30          


Leu Ala Asp Asp Gln Gly Phe Arg Asp Val Gly Tyr His Gly Ser Glu 
        35                  40                  45              


Ile Lys Thr Pro Thr Leu Asp Lys Leu Ala Ala Glu Gly Val Lys Leu 
    50                  55                  60                  


Glu Asn Tyr Tyr Val Gln Pro Ile Cys Thr Pro Ser Arg Ser Gln Phe 
65                  70                  75                  80  


Ile Thr Gly Lys Tyr Gln Ile His Thr Gly Leu Gln His Ser Ile Ile 
                85                  90                  95      


Arg Pro Thr Gln Pro Asn Cys Leu Pro Leu Asp Asn Ala Thr Leu Pro 
            100                 105                 110         


Gln Lys Leu Lys Glu Val Gly Tyr Ser Thr His Met Val Gly Lys Trp 
        115                 120                 125             


His Leu Gly Phe Tyr Arg Lys Glu Cys Met Pro Thr Arg Arg Gly Phe 
    130                 135                 140                 


Asp Thr Phe Phe Gly Ser Leu Leu Gly Ser Gly Asp Tyr Tyr Thr His 
145                 150                 155                 160 


Tyr Lys Cys Asp Ser Pro Gly Met Cys Gly Tyr Asp Leu Tyr Glu Asn 
                165                 170                 175     


Asp Asn Ala Ala Trp Asp Tyr Asp Asn Gly Ile Tyr Ser Thr Gln Met 
            180                 185                 190         


Tyr Thr Gln Arg Val Gln Gln Ile Leu Ala Ser His Asn Pro Thr Lys 
        195                 200                 205             


Pro Ile Phe Leu Tyr Ile Ala Tyr Gln Ala Val His Ser Pro Leu Gln 
    210                 215                 220                 


Ala Pro Gly Arg Tyr Phe Glu His Tyr Arg Ser Ile Ile Asn Ile Asn 
225                 230                 235                 240 


Arg Arg Arg Tyr Ala Ala Met Leu Ser Cys Leu Asp Glu Ala Ile Asn 
                245                 250                 255     


Asn Val Thr Leu Ala Leu Lys Thr Tyr Gly Phe Tyr Asn Asn Ser Ile 
            260                 265                 270         


Ile Ile Tyr Ser Ser Asp Asn Gly Gly Gln Pro Thr Ala Gly Gly Ser 
        275                 280                 285             


Asn Trp Pro Leu Arg Gly Ser Lys Gly Thr Tyr Trp Glu Gly Gly Ile 
    290                 295                 300                 


Arg Ala Val Gly Phe Val His Ser Pro Leu Leu Lys Asn Lys Gly Thr 
305                 310                 315                 320 


Val Cys Lys Glu Leu Val His Ile Thr Asp Trp Tyr Pro Thr Leu Ile 
                325                 330                 335     


Ser Leu Ala Glu Gly Gln Ile Asp Glu Asp Ile Gln Leu Asp Gly Tyr 
            340                 345                 350         


Asp Ile Trp Glu Thr Ile Ser Glu Gly Leu Arg Ser Pro Arg Val Asp 
        355                 360                 365             


Ile Leu His Asn Ile Asp Pro Ile Tyr Thr Lys Ala Lys Asn Gly Ser 
    370                 375                 380                 


Trp Ala Ala Gly Tyr Gly Ile Trp Asn Thr Ala Ile Gln Ser Ala Ile 
385                 390                 395                 400 


Arg Val Gln His Trp Lys Leu Leu Thr Gly Asn Pro Gly Tyr Ser Asp 
                405                 410                 415     


Trp Val Pro Pro Gln Ser Phe Ser Asn Leu Gly Pro Asn Arg Trp His 
            420                 425                 430         


Asn Glu Arg Ile Thr Leu Ser Thr Gly Lys Ser Val Trp Leu Phe Asn 
        435                 440                 445             


Ile Thr Ala Asp Pro Tyr Glu Arg Val Asp Leu Ser Asn Arg Tyr Pro 
    450                 455                 460                 


Gly Ile Val Lys Lys Leu Leu Arg Arg Leu Ser Gln Phe Asn Lys Thr 
465                 470                 475                 480 


Ala Val Pro Val Arg Tyr Pro Pro Lys Asp Pro Arg Ser Asn Pro Arg 
                485                 490                 495     


Leu Asn Gly Gly Val Trp Gly Pro Trp Tyr Lys Glu Glu Thr Lys Lys 
            500                 505                 510         


Lys Lys Pro Ser Lys Asn Gln Ala Glu Lys Lys Gln Lys Lys Ser Lys 
        515                 520                 525             


Lys Lys Lys Lys Lys Gln Gln Lys Ala Val Ser Gly Ser Thr Cys His 
    530                 535                 540                 


Ser Gly Val Thr Cys Gly 
545                 550 


<210>  2490
<211>  546
<212>  PRT
<213>  Homo Sapiens

<400>  2490

Lys Pro Ser Phe Val Ala Asp Gly Pro Gly Glu Ala Gly Glu Gln Pro 
1               5                   10                  15      


Ser Ala Ala Pro Pro Gln Pro Pro His Ile Ile Phe Ile Leu Thr Asp 
            20                  25                  30          


Asp Gln Gly Tyr His Asp Val Gly Tyr His Gly Ser Asp Ile Glu Thr 
        35                  40                  45              


Pro Thr Leu Asp Arg Leu Ala Ala Lys Gly Val Lys Leu Glu Asn Tyr 
    50                  55                  60                  


Tyr Ile Gln Pro Ile Cys Thr Pro Ser Arg Ser Gln Leu Leu Thr Gly 
65                  70                  75                  80  


Arg Tyr Gln Ile His Thr Gly Leu Gln His Ser Ile Ile Arg Pro Gln 
                85                  90                  95      


Gln Pro Asn Cys Leu Pro Leu Asp Gln Val Thr Leu Pro Gln Lys Leu 
            100                 105                 110         


Gln Glu Ala Gly Tyr Ser Thr His Met Val Gly Lys Trp His Leu Gly 
        115                 120                 125             


Phe Tyr Arg Lys Glu Cys Leu Pro Thr Arg Arg Gly Phe Asp Thr Phe 
    130                 135                 140                 


Leu Gly Ser Leu Thr Gly Asn Val Asp Tyr Tyr Thr Tyr Asp Asn Cys 
145                 150                 155                 160 


Asp Gly Pro Gly Val Cys Gly Phe Asp Leu His Glu Gly Glu Asn Val 
                165                 170                 175     


Ala Trp Gly Leu Ser Gly Gln Tyr Ser Thr Met Leu Tyr Ala Gln Arg 
            180                 185                 190         


Ala Ser His Ile Leu Ala Ser His Ser Pro Gln Arg Pro Leu Phe Leu 
        195                 200                 205             


Tyr Val Ala Phe Gln Ala Val His Thr Pro Leu Gln Ser Pro Arg Glu 
    210                 215                 220                 


Tyr Leu Tyr Arg Tyr Arg Thr Met Gly Asn Val Ala Arg Arg Lys Tyr 
225                 230                 235                 240 


Ala Ala Met Val Thr Cys Met Asp Glu Ala Val Arg Asn Ile Thr Trp 
                245                 250                 255     


Ala Leu Lys Arg Tyr Gly Phe Tyr Asn Asn Ser Val Ile Ile Phe Ser 
            260                 265                 270         


Ser Asp Asn Gly Gly Gln Thr Phe Ser Gly Gly Ser Asn Trp Pro Leu 
        275                 280                 285             


Arg Gly Arg Lys Gly Thr Tyr Trp Glu Gly Gly Val Arg Gly Leu Gly 
    290                 295                 300                 


Phe Val His Ser Pro Leu Leu Lys Arg Lys Gln Arg Thr Ser Arg Ala 
305                 310                 315                 320 


Leu Met His Ile Thr Asp Trp Tyr Pro Thr Leu Val Gly Leu Ala Gly 
                325                 330                 335     


Gly Thr Thr Ser Ala Ala Asp Gly Leu Asp Gly Tyr Asp Val Trp Pro 
            340                 345                 350         


Ala Ile Ser Glu Gly Arg Ala Ser Pro Arg Thr Glu Ile Leu His Asn 
        355                 360                 365             


Ile Asp Pro Leu Tyr Asn His Ala Gln His Gly Ser Leu Glu Gly Gly 
    370                 375                 380                 


Phe Gly Ile Trp Asn Thr Ala Val Gln Ala Ala Ile Arg Val Gly Glu 
385                 390                 395                 400 


Trp Lys Leu Leu Thr Gly Asp Pro Gly Tyr Gly Asp Trp Ile Pro Pro 
                405                 410                 415     


Gln Thr Leu Ala Thr Phe Pro Gly Ser Trp Trp Asn Leu Glu Arg Met 
            420                 425                 430         


Ala Ser Val Arg Gln Ala Val Trp Leu Phe Asn Ile Ser Ala Asp Pro 
        435                 440                 445             


Tyr Glu Arg Glu Asp Leu Ala Gly Gln Arg Pro Asp Val Val Arg Thr 
    450                 455                 460                 


Leu Leu Ala Arg Leu Ala Glu Tyr Asn Arg Thr Ala Ile Pro Val Arg 
465                 470                 475                 480 


Tyr Pro Ala Glu Asn Pro Arg Ala His Pro Asp Phe Asn Gly Gly Ala 
                485                 490                 495     


Trp Gly Pro Trp Ala Ser Asp Glu Glu Glu Glu Glu Glu Glu Gly Arg 
            500                 505                 510         


Ala Arg Ser Phe Ser Arg Gly Arg Arg Lys Lys Lys Cys Lys Ile Cys 
        515                 520                 525             


Lys Leu Arg Ser Phe Phe Arg Lys Leu Asn Thr Arg Leu Met Ser Gln 
    530                 535                 540                 


Arg Ile 
545     


<210>  2491
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  2491

Met Asp Ile Lys Met Gln Ile Gly Ser Arg Asn Phe Tyr Thr Leu Ser 
1               5                   10                  15      


Ile Asp Tyr Pro Arg Val Asn Tyr Pro Lys Gly Phe Arg Gly Tyr Cys 
            20                  25                  30          


Asn Gly Leu Met Ser Tyr Met Arg Gly Lys Met Gln Asn Ser Asp Cys 
        35                  40                  45              


Pro Lys Ile His Tyr Val Ile His Ala Pro Trp Lys Ala Ile Gln Lys 
    50                  55                  60                  


Phe Cys Lys Tyr Ser Asp Ser Phe Cys Glu Asn Tyr Asn Glu Tyr Cys 
65                  70                  75                  80  


Thr Leu Thr Gln Asp Ser Leu Pro Ile Thr Val Cys Ser Leu Ser His 
                85                  90                  95      


Gln Gln Pro Pro Thr Ser Cys Tyr Tyr Asn Ser Thr Leu Thr Asn Gln 
            100                 105                 110         


Lys Leu Tyr Leu Leu Cys Ser Arg Lys Tyr Glu Ala Asp Pro Ile Gly 
        115                 120                 125             


Ile Ala Gly Leu Tyr Ser Gly Ile 
    130                 135     


<210>  2492
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2492

Glu Ala Val Met Ser Thr Leu Glu His Leu His Val Asp Tyr Pro Gln 
1               5                   10                  15      


Asn Asp Val Pro Val Pro Ala Arg Tyr Cys Asn His Met Ile Ile Gln 
            20                  25                  30          


Arg Val Ile Arg Glu Pro Asp His Thr Cys Lys Lys Glu His Val Phe 
        35                  40                  45              


Ile His Glu Arg Pro Arg Lys Ile Asn Gly Ile Cys Ile Ser Pro Lys 
    50                  55                  60                  


Lys Val Ala Cys Gln Asn Leu Ser Ala Ile Phe Cys Phe Gln Ser Glu 
65                  70                  75                  80  


Thr Lys Phe Lys Met Thr Val Cys Gln Leu Ile Glu Gly Thr Arg Tyr 
                85                  90                  95      


Pro Ala Cys Arg Tyr His Tyr Ser Pro Thr Glu Gly Phe Val Leu Val 
            100                 105                 110         


Thr Cys Asp Asp Leu Arg Pro Asp Ser Phe Leu Gly Tyr Val Lys 
        115                 120                 125         


<210>  2493
<211>  190
<212>  PRT
<213>  Homo Sapiens

<400>  2493

Leu His Met Ala Thr Ala Val Leu Glu Glu Ser Asp Gln Pro Leu Asn 
1               5                   10                  15      


Glu Phe Trp Ser Ser Asp Ser Gln Asp Lys Ala Glu Ala Thr Glu Glu 
            20                  25                  30          


Gly Asp Gly Thr Gln Thr Thr Glu Thr Leu Val Leu Ser Asn Lys Glu 
        35                  40                  45              


Val Val Gln Pro Gly Trp Pro Glu Asp Pro Ile Leu Gly Glu Asp Glu 
    50                  55                  60                  


Val Gly Gly Asn Lys Met Leu Arg Ala Ser Ala Leu Phe Gln Ser Asn 
65                  70                  75                  80  


Lys Asp Tyr Leu Arg Leu Asp Gln Thr Asp Arg Glu Cys Asn Asp Met 
                85                  90                  95      


Met Ala His Lys Met Lys Glu Pro Ser Gln Ser Cys Ile Ala Gln Tyr 
            100                 105                 110         


Ala Phe Ile His Glu Asp Leu Asn Thr Val Lys Ala Val Cys Asn Ser 
        115                 120                 125             


Pro Val Ile Ala Cys Glu Leu Lys Gly Gly Lys Cys His Lys Ser Ser 
    130                 135                 140                 


Arg Pro Phe Asp Leu Thr Leu Cys Glu Leu Ser Gln Pro Asp Gln Val 
145                 150                 155                 160 


Thr Pro Asn Cys Asn Tyr Leu Thr Ser Val Ile Lys Lys His Ile Ile 
                165                 170                 175     


Ile Thr Cys Asn Asp Met Lys Arg Gln Leu Pro Thr Gly Gln 
            180                 185                 190 


<210>  2494
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  2494

Gln Val Thr Pro Val Met Lys Cys Trp Gly Lys Ser Gly Arg Cys Arg 
1               5                   10                  15      


Thr Thr Cys Lys Glu Ser Glu Val Tyr Tyr Ile Leu Cys Lys Thr Glu 
            20                  25                  30          


Ala Lys Cys Cys Val Asp Pro Lys Tyr Val Pro Val Lys Pro Lys Leu 
        35                  40                  45              


Thr Asp Thr Asn Thr Ser Leu Glu Ser Thr Ser Ala Val 
    50                  55                  60      


<210>  2495
<211>  322
<212>  PRT
<213>  Homo Sapiens

<400>  2495

Gly Ser Pro Val Leu Arg Asn Phe Thr Phe Ala Val Ser Trp Arg Thr 
1               5                   10                  15      


Glu Lys Ile Leu Tyr Arg Leu Asp Val Gly Trp Pro Lys His Pro Glu 
            20                  25                  30          


Tyr Phe Thr Gly Thr Thr Phe Cys Val Ala Val Asp Ser Leu Asn Gly 
        35                  40                  45              


Leu Val Tyr Ile Gly Gln Arg Gly Asp Asn Ile Pro Lys Ile Leu Val 
    50                  55                  60                  


Phe Thr Glu Asp Gly Tyr Phe Leu Arg Ala Trp Asn Tyr Thr Val Asp 
65                  70                  75                  80  


Thr Pro His Gly Ile Phe Ala Ala Ser Thr Leu Tyr Glu Gln Ser Val 
                85                  90                  95      


Trp Ile Thr Asp Val Gly Ser Gly Phe Phe Gly His Thr Val Lys Lys 
            100                 105                 110         


Tyr Ser Ser Phe Gly Asp Leu Val Gln Val Leu Gly Thr Pro Gly Lys 
        115                 120                 125             


Lys Gly Thr Ser Leu Asn Pro Leu Gln Phe Asp Asn Pro Ala Glu Leu 
    130                 135                 140                 


Tyr Val Glu Asp Thr Gly Asp Ile Tyr Ile Val Asp Gly Asp Gly Gly 
145                 150                 155                 160 


Leu Asn Asn Arg Leu Ile Lys Leu Ser Gln Asp Phe Met Ile Leu Trp 
                165                 170                 175     


Leu His Gly Glu Asn Gly Thr Gly Pro Ala Lys Phe Asn Ile Pro His 
            180                 185                 190         


Ser Val Thr Leu Asp Ser Ala Gly Arg Val Trp Val Ala Asp Arg Gly 
        195                 200                 205             


Asn Lys Arg Ile Gln Val Phe Asp Lys Asp Thr Gly Glu Trp Leu Gly 
    210                 215                 220                 


Ala Trp Asn Asn Cys Phe Thr Glu Glu Gly Pro Ser Ser Val Arg Phe 
225                 230                 235                 240 


Thr Pro Asp Gly Lys Tyr Leu Ile Val Ala Gln Leu Asn Leu Ser Arg 
                245                 250                 255     


Leu Ser Val Val Ala Ala Pro Pro Val Gly Ser Ile Gly Glu Cys Ser 
            260                 265                 270         


Val Ile Ser Thr Ile Gln Leu Ala Asp Gln Val Leu Pro His Leu Leu 
        275                 280                 285             


Glu Val Asp Arg Lys Thr Gly Ala Val Tyr Val Ala Glu Ile Gly Ala 
    290                 295                 300                 


Lys Gln Val Gln Lys Tyr Val Pro Leu Asn Ser Tyr Val Pro Ser Phe 
305                 310                 315                 320 


Gly Ser 
        


<210>  2496
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  2496

Ala Glu Pro Phe Ser Pro Pro Arg Gly Asp Ser Ala Gln Ser Thr Ala 
1               5                   10                  15      


Cys Asp Arg His Met Ala Val Gln Arg Arg Leu Asp Val Met Glu Glu 
            20                  25                  30          


Met Val Glu Lys Thr Val Asp His Leu Gly Thr Glu Val Lys Gly Leu 
        35                  40                  45              


Leu Gly Leu Leu Glu Glu Leu Ala Trp Asn Leu Pro Pro Gly Pro Phe 
    50                  55                  60                  


Ser Pro Ala Pro Asp Leu Leu Gly Asp Gly Phe 
65                  70                  75  


<210>  2497
<211>  405
<212>  PRT
<213>  Homo Sapiens

<400>  2497

Val Glu Ala Thr Ser Val Leu Leu Pro Thr Asp Ile Lys Phe Gly Ile 
1               5                   10                  15      


Val Phe Asp Ala Gly Ser Ser His Thr Ser Leu Phe Leu Tyr Gln Trp 
            20                  25                  30          


Leu Ala Asn Lys Glu Asn Gly Thr Gly Val Val Ser Gln Ala Leu Ala 
        35                  40                  45              


Cys Gln Val Glu Gly Pro Gly Ile Ser Ser Tyr Thr Ser Asn Ala Ala 
    50                  55                  60                  


Gln Ala Gly Glu Ser Leu Gln Gly Cys Leu Glu Glu Ala Leu Val Leu 
65                  70                  75                  80  


Ile Pro Glu Ala Gln His Arg Lys Thr Pro Thr Phe Leu Gly Ala Thr 
                85                  90                  95      


Ala Gly Met Arg Leu Leu Ser Arg Lys Asn Ser Ser Gln Ala Arg Asp 
            100                 105                 110         


Ile Phe Ala Ala Val Thr Gln Val Leu Gly Arg Ser Pro Val Asp Phe 
        115                 120                 125             


Trp Gly Ala Glu Leu Leu Ala Gly Gln Ala Glu Gly Ala Phe Gly Trp 
    130                 135                 140                 


Ile Thr Val Asn Tyr Gly Leu Gly Thr Leu Val Lys Tyr Ser Phe Thr 
145                 150                 155                 160 


Gly Glu Trp Ile Gln Pro Pro Glu Glu Met Leu Val Gly Ala Leu Asp 
                165                 170                 175     


Met Gly Gly Ala Ser Thr Gln Ile Thr Phe Val Pro Gly Gly Pro Ile 
            180                 185                 190         


Leu Asp Lys Ser Thr Gln Ala Asp Phe Arg Leu Tyr Gly Ser Asp Tyr 
        195                 200                 205             


Ser Val Tyr Thr His Ser Tyr Leu Cys Phe Gly Arg Asp Gln Met Leu 
    210                 215                 220                 


Ser Arg Leu Leu Val Gly Leu Val Gln Ser Arg Pro Ala Ala Leu Leu 
225                 230                 235                 240 


Arg His Pro Cys Tyr Leu Ser Gly Tyr Gln Thr Thr Leu Ala Leu Gly 
                245                 250                 255     


Pro Leu Tyr Glu Ser Pro Cys Val His Ala Thr Pro Pro Leu Ser Leu 
            260                 265                 270         


Pro Gln Asn Leu Thr Val Glu Gly Thr Gly Asn Pro Gly Ala Cys Val 
        275                 280                 285             


Ser Ala Ile Arg Glu Leu Phe Asn Phe Ser Ser Cys Gln Gly Gln Glu 
    290                 295                 300                 


Asp Cys Ala Phe Asp Gly Val Tyr Gln Pro Pro Leu Arg Gly Gln Phe 
305                 310                 315                 320 


Tyr Val Glu Ala Ser Tyr Pro Gly Gln Asp Arg Trp Leu Arg Asp Tyr 
                325                 330                 335     


Cys Ala Ser Gly Leu Tyr Ile Leu Thr Leu Leu His Glu Gly Tyr Gly 
            340                 345                 350         


Phe Ser Glu Glu Thr Trp Pro Ser Leu Glu Phe Arg Lys Gln Ala Gly 
        355                 360                 365             


Gly Val Asp Ile Gly Trp Thr Leu Gly Tyr Met Leu Asn Leu Thr Gly 
    370                 375                 380                 


Met Ile Pro Ala Asp Ala Pro Ala Gln Trp Arg Ala Glu Ser Tyr Gly 
385                 390                 395                 400 


Val Trp Val Ala Lys 
                405 


<210>  2498
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2498

Arg Met Ser Ser Leu Ser Phe Leu Asn Ile Glu Lys Thr Glu Ile Leu 
1               5                   10                  15      


Phe Phe Thr Lys Thr Glu Glu Thr Ile Leu Val Ser Ser Ser Tyr Glu 
            20                  25                  30          


Asn Lys Arg Pro Asn Ser Ser His Leu Phe Val Lys Ile Glu Asp Pro 
        35                  40                  45              


Lys Ile Leu Gln Met Val Asn Val Ala Lys Lys Ile Ser Ser Asp Ala 
    50                  55                  60                  


Thr Asn Phe Thr Ile Asn Leu Val Thr Asp Glu Glu Gly Glu Thr Asn 
65                  70                  75                  80  


Val Thr Ile Gln Leu Trp Asp Ser Glu Gly Arg Gln Glu Arg Leu Ile 
                85                  90                  95      


Glu Glu Ile Lys Asn Val Lys Val Lys Val Leu Lys Gln Lys Asp Ser 
            100                 105                 110         


Leu Leu Gln Ala Pro Met His Ile Asp Arg Asn 
        115                 120             


<210>  2499
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2499

Asp Pro Arg Asp Leu Lys Ser Cys Asn Arg Pro Cys Val Trp Ser Arg 
1               5                   10                  15      


Leu Leu Lys Pro Asn Ser Ser Leu Ser Asn Leu Glu Thr Ala Tyr Phe 
            20                  25                  30          


Pro Gln Asn Leu Arg Phe Leu Arg Pro Trp Tyr Phe Ser Arg Ser His 
        35                  40                  45              


Leu Asn Tyr His Gln Lys Ala Pro Ala Arg Trp Glu Trp Leu Tyr Ser 
    50                  55                  60                  


Ile Tyr Arg Lys Gly Thr Lys Ala Gln Arg Arg Asn Val Leu Arg Ser 
65                  70                  75                  80  


Pro Cys Ala Pro Pro Gln Pro Ser Trp Pro Cys Ser Val Ile 
                85                  90                  


<210>  2500
<211>  893
<212>  PRT
<213>  Homo Sapiens

<400>  2500

Ala Thr Glu Ala Arg Leu His Pro Glu Gly Ser Ser Arg Lys Gln Gln 
1               5                   10                  15      


Arg Ala Gln Ser Pro Ala Arg Pro Arg Asp Ser Ser Leu Arg Gln Thr 
            20                  25                  30          


Ile Ala Ala Thr Arg Ser Pro Val Gly Ala Gly Thr Lys Leu Asn Ser 
        35                  40                  45              


Val Arg Gln Gln Gln Leu Gln Gln Gln Gln Gln Gln Gly Asn Lys Thr 
    50                  55                  60                  


Gly Ser Arg Thr Gly Pro Pro Ala Ser Ile Arg Gly Gly Gly Gly Gly 
65                  70                  75                  80  


Ala Glu Lys Ala Thr Pro Leu Ala Pro Lys Gly Ala Ala Pro Gly Ala 
                85                  90                  95      


Val Gln Pro Val Ala Gly Ala Glu Ala Ala Pro Ala Ala Thr Leu Ala 
            100                 105                 110         


Ala Leu Gly Gly Arg Arg Pro Gly Pro Pro Glu Glu Pro Pro Arg Glu 
        115                 120                 125             


Leu Glu Ser Val Pro Ser Lys Leu Gly Glu Pro Pro Pro Leu Gly Glu 
    130                 135                 140                 


Gly Gly Gly Gly Gly Gly Glu Gly Gly Gly Ala Gly Gly Gly Ser Gly 
145                 150                 155                 160 


Glu Arg Glu Gly Gly Ala Pro Gln Pro Pro Pro Pro Arg Gly Trp Arg 
                165                 170                 175     


Gly Lys Gly Val Arg Ala Gln Gln Arg Gly Gly Ser Gly Gly Glu Gly 
            180                 185                 190         


Ala Ser Pro Ser Pro Ser Ser Ser Ser Ala Gly Lys Thr Pro Gly Thr 
        195                 200                 205             


Gly Ser Arg Asn Ser Gly Ser Gly Val Ala Gly Gly Gly Ser Gly Gly 
    210                 215                 220                 


Gly Gly Ser Tyr Trp Lys Glu Gly Cys Leu Gln Ser Glu Leu Ile Gln 
225                 230                 235                 240 


Phe His Leu Lys Lys Glu Arg Ala Ala Ala Ala Ala Ala Ala Ala Gln 
                245                 250                 255     


Met His Ala Lys Asn Gly Gly Gly Ser Ser Ser Arg Ser Ser Pro Val 
            260                 265                 270         


Ser Gly Pro Pro Ala Val Cys Glu Thr Leu Ala Val Ala Ser Ala Ser 
        275                 280                 285             


Pro Met Ala Ala Ala Ala Glu Gly Pro Gln Gln Ser Ala Glu Gly Ser 
    290                 295                 300                 


Ala Ser Gly Gly Gly Met Gln Ala Ala Ala Pro Pro Ser Ser Gln Pro 
305                 310                 315                 320 


His Pro Gln Gln Leu Gln Glu Gln Glu Glu Met Gln Glu Glu Met Glu 
                325                 330                 335     


Lys Leu Arg Glu Glu Asn Glu Thr Leu Lys Asn Glu Ile Asp Glu Leu 
            340                 345                 350         


Arg Thr Glu Met Asp Glu Met Arg Asp Thr Phe Phe Glu Glu Asp Ala 
        355                 360                 365             


Cys Gln Leu Gln Glu Met Arg His Glu Leu Glu Arg Ala Asn Lys Asn 
    370                 375                 380                 


Cys Arg Ile Leu Gln Tyr Arg Leu Arg Lys Ala Glu Arg Lys Arg Leu 
385                 390                 395                 400 


Arg Tyr Ala Gln Thr Gly Glu Ile Asp Gly Glu Leu Leu Arg Ser Leu 
                405                 410                 415     


Glu Gln Asp Leu Lys Val Ala Lys Asp Val Ser Val Arg Leu His His 
            420                 425                 430         


Glu Leu Glu Asn Val Glu Glu Lys Arg Thr Thr Thr Glu Asp Glu Asn 
        435                 440                 445             


Glu Lys Leu Arg Gln Gln Leu Ile Glu Val Glu Ile Ala Lys Gln Ala 
    450                 455                 460                 


Leu Gln Asn Glu Leu Glu Lys Met Lys Glu Leu Ser Leu Lys Arg Arg 
465                 470                 475                 480 


Gly Ser Lys Asp Leu Pro Lys Ser Glu Lys Lys Ala Gln Gln Thr Pro 
                485                 490                 495     


Thr Glu Glu Asp Asn Glu Asp Leu Lys Cys Gln Leu Gln Phe Val Lys 
            500                 505                 510         


Glu Glu Ala Ala Leu Met Arg Lys Lys Met Ala Lys Ile Asp Lys Glu 
        515                 520                 525             


Lys Asp Arg Phe Glu His Glu Leu Gln Lys Tyr Arg Ser Phe Tyr Gly 
    530                 535                 540                 


Asp Leu Asp Ser Pro Leu Pro Lys Gly Glu Ala Gly Gly Pro Pro Ser 
545                 550                 555                 560 


Thr Arg Glu Ala Glu Leu Lys Leu Arg Leu Arg Leu Val Glu Glu Glu 
                565                 570                 575     


Ala Asn Ile Leu Gly Arg Lys Ile Val Glu Leu Glu Val Glu Asn Arg 
            580                 585                 590         


Gly Leu Lys Ala Glu Leu Asp Asp Leu Arg Gly Asp Asp Phe Asn Gly 
        595                 600                 605             


Ser Ala Asn Pro Leu Met Arg Glu Gln Ser Glu Ser Leu Ser Glu Leu 
    610                 615                 620                 


Arg Gln His Leu Gln Leu Val Glu Asp Glu Thr Glu Leu Leu Arg Arg 
625                 630                 635                 640 


Asn Val Ala Asp Leu Glu Glu Gln Asn Lys Arg Ile Thr Ala Glu Leu 
                645                 650                 655     


Asn Lys Tyr Lys Tyr Lys Ser Gly Gly His Asp Ser Ala Arg His His 
            660                 665                 670         


Asp Asn Ala Lys Thr Glu Ala Leu Gln Glu Glu Leu Lys Ala Ala Arg 
        675                 680                 685             


Leu Gln Ile Asn Glu Leu Ser Gly Lys Val Met Gln Leu Gln Tyr Glu 
    690                 695                 700                 


Asn Arg Val Leu Met Ser Asn Met Gln Arg Tyr Asp Leu Ala Ser His 
705                 710                 715                 720 


Leu Gly Ile Arg Gly Ser Pro Arg Asp Ser Asp Ala Glu Ser Asp Ala 
                725                 730                 735     


Gly Lys Lys Glu Ser Asp Asp Asp Ser Arg Pro Pro His Arg Lys Arg 
            740                 745                 750         


Glu Gly Pro Ile Gly Gly Glu Ser Asp Ser Glu Glu Val Arg Asn Ile 
        755                 760                 765             


Arg Cys Leu Thr Pro Thr Arg Ser Phe Tyr Pro Ala Pro Gly Pro Trp 
    770                 775                 780                 


Pro Lys Ser Phe Ser Asp Arg Gln Gln Met Lys Asp Ile Arg Ser Glu 
785                 790                 795                 800 


Ala Glu Arg Leu Gly Lys Thr Ile Asp Arg Leu Ile Ala Asp Thr Ser 
                805                 810                 815     


Thr Ile Ile Thr Glu Ala Arg Ile Tyr Val Ala Asn Gly Asp Leu Phe 
            820                 825                 830         


Gly Leu Met Asp Glu Glu Asp Asp Gly Ser Arg Ile Arg Glu His Glu 
        835                 840                 845             


Leu Leu Tyr Arg Ile Asn Ala Gln Met Lys Ala Phe Arg Lys Glu Leu 
    850                 855                 860                 


Gln Thr Phe Ile Asp Arg Leu Glu Val Pro Lys Ser Ala Asp Asp Arg 
865                 870                 875                 880 


Gly Ala Glu Glu Pro Ile Ser Val Ser Gln Met Phe Gln 
                885                 890             


<210>  2501
<211>  194
<212>  PRT
<213>  Homo Sapiens

<400>  2501

Ser Gly Cys Arg Ala Gly Thr Gly Ala Arg Gly Ala Gly Ala Glu Gly 
1               5                   10                  15      


Arg Glu Gly Glu Ala Cys Gly Thr Val Gly Leu Leu Leu Glu His Ser 
            20                  25                  30          


Phe Glu Ile Asp Asp Ser Ala Asn Phe Arg Lys Arg Gly Ser Leu Leu 
        35                  40                  45              


Trp Asn Gln Gln Asp Gly Thr Leu Ser Leu Ser Gln Arg Gln Leu Ser 
    50                  55                  60                  


Glu Glu Glu Arg Gly Arg Leu Arg Asp Val Ala Ala Leu Asn Gly Leu 
65                  70                  75                  80  


Tyr Arg Val Arg Ile Pro Arg Arg Pro Gly Ala Leu Asp Gly Leu Glu 
                85                  90                  95      


Ala Gly Gly Tyr Val Ser Ser Phe Val Pro Ala Cys Ser Leu Val Glu 
            100                 105                 110         


Ser His Leu Ser Asp Gln Leu Thr Leu His Val Asp Val Ala Gly Asn 
        115                 120                 125             


Val Val Gly Val Ser Val Val Thr His Pro Gly Gly Cys Arg Gly His 
    130                 135                 140                 


Glu Val Glu Asp Val Asp Leu Glu Leu Phe Asn Thr Ser Val Gln Leu 
145                 150                 155                 160 


Gln Pro Pro Thr Thr Ala Pro Gly Pro Glu Thr Ala Ala Phe Ile Glu 
                165                 170                 175     


Arg Leu Glu Met Glu Gln Ala Gln Lys Ala Lys Asn Pro Gln Glu Gln 
            180                 185                 190         


Lys Ser 
        


<210>  2502
<211>  380
<212>  PRT
<213>  Homo Sapiens

<400>  2502

Tyr Asp Lys Lys Gly Asn Asn Ala Asn Pro Glu Ala Asn Met Asn Ile 
1               5                   10                  15      


Ser Gln Ile Ile Ser Tyr Trp Gly Tyr Pro Tyr Glu Glu Tyr Asp Val 
            20                  25                  30          


Thr Thr Lys Asp Gly Tyr Ile Leu Gly Ile Tyr Arg Ile Pro His Gly 
        35                  40                  45              


Arg Gly Cys Pro Gly Arg Thr Ala Pro Lys Pro Ala Val Tyr Leu Gln 
    50                  55                  60                  


His Gly Leu Ile Ala Ser Ala Ser Asn Trp Ile Cys Asn Leu Pro Asn 
65                  70                  75                  80  


Asn Ser Leu Ala Phe Leu Leu Ala Asp Ser Gly Tyr Asp Val Trp Leu 
                85                  90                  95      


Gly Asn Ser Arg Gly Asn Thr Trp Ser Arg Lys His Leu Lys Leu Ser 
            100                 105                 110         


Pro Lys Ser Pro Glu Tyr Trp Ala Phe Ser Leu Asp Glu Met Ala Lys 
        115                 120                 125             


Tyr Asp Leu Pro Ala Thr Ile Asn Phe Ile Ile Glu Lys Thr Gly Gln 
    130                 135                 140                 


Lys Arg Leu Tyr Tyr Val Gly His Ser Gln Gly Thr Thr Ile Ala Phe 
145                 150                 155                 160 


Ile Ala Phe Ser Thr Asn Pro Glu Leu Ala Lys Lys Ile Lys Ile Phe 
                165                 170                 175     


Phe Ala Leu Ala Pro Val Val Thr Val Lys Tyr Thr Gln Ser Pro Met 
            180                 185                 190         


Lys Lys Leu Thr Thr Leu Ser Arg Arg Val Val Lys Val Leu Phe Gly 
        195                 200                 205             


Asp Lys Met Phe His Pro His Thr Leu Phe Asp Gln Phe Ile Ala Thr 
    210                 215                 220                 


Lys Val Cys Asn Arg Lys Leu Phe Arg Arg Ile Cys Ser Asn Phe Leu 
225                 230                 235                 240 


Phe Thr Leu Ser Gly Phe Asp Pro Gln Asn Leu Asn Met Ser Arg Leu 
                245                 250                 255     


Asp Val Tyr Leu Ser His Asn Pro Ala Gly Thr Ser Val Gln Asn Met 
            260                 265                 270         


Leu His Trp Ala Gln Ala Val Asn Ser Gly Gln Leu Gln Ala Phe Asp 
        275                 280                 285             


Trp Gly Asn Ser Asp Gln Asn Met Met His Phe His Gln Leu Thr Pro 
    290                 295                 300                 


Pro Leu Tyr Asn Ile Thr Lys Met Glu Val Pro Thr Ala Ile Trp Asn 
305                 310                 315                 320 


Gly Gly Gln Asp Ile Val Ala Asp Pro Lys Asp Val Glu Asn Leu Leu 
                325                 330                 335     


Pro Gln Ile Ala Asn Leu Ile Tyr Tyr Lys Leu Ile Pro His Tyr Asn 
            340                 345                 350         


His Val Asp Phe Tyr Leu Gly Glu Asp Ala Pro Gln Glu Ile Tyr Gln 
        355                 360                 365             


Asp Leu Ile Ile Leu Met Glu Glu Tyr Leu Gln Asn 
    370                 375                 380 


<210>  2503
<211>  427
<212>  PRT
<213>  Homo Sapiens

<400>  2503

Gln Ala Met Glu Gly Val Lys Cys Gly Gly Val Leu Ser Ala Pro Ser 
1               5                   10                  15      


Gly Asn Phe Ser Ser Pro Asn Phe Pro Arg Leu Tyr Pro Tyr Asn Thr 
            20                  25                  30          


Glu Cys Ser Trp Leu Ile Val Val Ala Glu Gly Ser Ser Val Leu Leu 
        35                  40                  45              


Thr Phe His Ala Phe Asp Leu Glu Tyr His Asp Thr Cys Ser Phe Asp 
    50                  55                  60                  


Phe Leu Glu Ile Tyr Asn Gly Ala Ser Pro Asp Lys Gly Asn Leu Leu 
65                  70                  75                  80  


Gly Arg Phe Cys Gly Lys Val Pro Pro Pro Pro Phe Thr Ser Ser Trp 
                85                  90                  95      


His Val Met Ser Val Ile Phe His Ser Asp Lys His Val Ala Ser His 
            100                 105                 110         


Gly Phe Ser Ala Gly Tyr Gln Lys Asp Val Cys Gly Gly Val Leu Thr 
        115                 120                 125             


Gly Leu Ser Gly Val Leu Thr Ser Pro Glu Tyr Pro Asn Asn Tyr Pro 
    130                 135                 140                 


Asn Ser Met Glu Cys His Trp Val Ile Arg Ala Ala Gly Pro Ala His 
145                 150                 155                 160 


Val Lys Leu Val Phe Val Asp Phe Gln Val Glu Gly Asn Glu Glu Cys 
                165                 170                 175     


Thr Tyr Asp Tyr Val Ala Val Leu Gly Gly Pro Gly Pro Thr Arg Gly 
            180                 185                 190         


His His Tyr Cys Gly Ser Thr Arg Pro Pro Thr Leu Val Ser Leu Gly 
        195                 200                 205             


His Glu Leu Gln Val Val Phe Lys Ser Asp Phe Asn Ile Gly Gly Arg 
    210                 215                 220                 


Gly Phe Lys Ala Tyr Tyr Phe Ser Gly Glu Cys Gln Glu Val Tyr Met 
225                 230                 235                 240 


Ala Met Arg Gly Asn Phe Ser Ser Pro Gln Tyr Pro Ser Ser Tyr Pro 
                245                 250                 255     


Asn Asn Ile Arg Cys His Trp Thr Ile Arg Leu Pro Pro Gly Tyr Gln 
            260                 265                 270         


Val Lys Val Phe Phe Leu Asp Leu Asp Leu Glu Glu Pro Asn Ser Leu 
        275                 280                 285             


Thr Lys Thr Cys Asp Phe Asp His Leu Ala Ala Phe Asp Gly Ala Ser 
    290                 295                 300                 


Glu Glu Ala Pro Leu Leu Gly Asn Trp Cys Gly His His Leu Pro Pro 
305                 310                 315                 320 


Pro Val Thr Ser Ser His Asn Gln Leu Leu Leu Leu Leu His Thr Asp 
                325                 330                 335     


Arg Ser Thr Thr Arg Arg Gly Phe Ser Val Ala Tyr Ile Gly Gly Gln 
            340                 345                 350         


Leu Gly Cys Gly Ser Gly Ser Thr Glu Gly Glu Gly Glu Ala Leu Gln 
        355                 360                 365             


Pro Gln Ser Leu Gln Ser Pro Ser Ser Ile Pro Pro Val Cys Pro Ala 
    370                 375                 380                 


Pro Pro Met Asn Gly Leu Leu Gln Leu Leu Leu His Trp Leu His Pro 
385                 390                 395                 400 


Cys Pro Leu Ser Gly Pro Leu Arg Leu Asp Gly Thr Ala Pro Ala Cys 
                405                 410                 415     


Phe His Tyr Cys Arg Ala Ser Phe Pro Ser Phe 
            420                 425         


<210>  2504
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  2504

Trp Cys Ser Glu Glu Glu Met Gly Gly Asn Asn Lys Ile Val Gln Asp 
1               5                   10                  15      


Pro Met Phe Leu Ala Thr Val Glu Phe Ala Leu Asn Thr Phe Asn Val 
            20                  25                  30          


Gln Ser Lys Glu Glu His Ala Tyr Arg Leu Leu Arg Val Leu Ser Ser 
        35                  40                  45              


Trp Arg Glu Asp Ser Met Asp Arg Lys Trp Arg Gly Lys Met Val Phe 
    50                  55                  60                  


Ser Met Asn Leu Gln Leu Arg Gln Thr Val Cys Arg Lys Phe Glu Asp 
65                  70                  75                  80  


Asp Ile Asp Asn Cys Pro Phe Gln Glu Ser Leu Glu Leu Asn Asn Val 
                85                  90                  95      


Arg Gln Gly Ile Ser Phe Pro Gln Val His Ser Cys Gly Cys Cys Met 
            100                 105                 110         


Gly Cys Gly Val Gly Thr Gly Ala Ala Asp Lys Ala Ile Pro Arg Asp 
        115                 120                 125             


Lys Gly Lys 
    130     


<210>  2505
<211>  728
<212>  PRT
<213>  Homo Sapiens

<400>  2505

Ile Val Leu Thr Gly Thr Ser Glu Pro Pro Asp Ala Gln Thr Val Ala 
1               5                   10                  15      


Pro Ala Glu Asp Glu Thr Leu Gln Asn Glu Ala Asp Asn Gln Glu Asn 
            20                  25                  30          


Val Leu Ser Gln Leu Leu Gly Asp Tyr Asp Lys Val Lys Ala Met Ser 
        35                  40                  45              


Glu Gly Ser Asp Cys Gln Cys Lys Cys Val Val Arg Pro Leu Gly Arg 
    50                  55                  60                  


Asp Ala Cys Gln Arg Ile Asn Ala Gly Ala Ser Arg Lys Glu Asp Phe 
65                  70                  75                  80  


Tyr Thr Val Glu Thr Ile Thr Ser Gly Ser Ser Cys Lys Cys Ala Cys 
                85                  90                  95      


Val Ala Pro Pro Ser Ala Leu Asn Pro Cys Glu Gly Asp Phe Arg Leu 
            100                 105                 110         


Gln Lys Leu Arg Glu Ala Asp Ser Gln Asp Leu Lys Leu Ser Thr Ile 
        115                 120                 125             


Ile Asp Met Leu Glu Gly Ala Phe Tyr Gly Leu Asp Leu Leu Lys Leu 
    130                 135                 140                 


His Ser Val Thr Thr Lys Leu Val Gly Arg Val Asp Lys Leu Glu Glu 
145                 150                 155                 160 


Glu Val Ser Lys Asn Leu Thr Lys Glu Asn Glu Gln Ile Lys Glu Asp 
                165                 170                 175     


Met Glu Glu Ile Arg Thr Glu Met Asn Lys Arg Gly Lys Glu Asn Cys 
            180                 185                 190         


Ser Glu Asn Ile Leu Asp Ser Met Pro Asp Ile Arg Ser Ala Leu Gln 
        195                 200                 205             


Arg Asp Ala Ala Ala Ala Tyr Ala His Pro Glu Tyr Glu Glu Arg Phe 
    210                 215                 220                 


Leu Gln Glu Glu Thr Val Ser Gln Gln Ile Asn Ser Ile Glu Leu Leu 
225                 230                 235                 240 


Gln Thr Arg Pro Leu Ala Leu Pro Glu Val Val Lys Ser Gln Arg Pro 
                245                 250                 255     


Leu Gln Arg Gln Val His Leu Arg Gly Arg Pro Ala Ser Gln Pro Thr 
            260                 265                 270         


Val Ile Arg Gly Ile Thr Tyr Tyr Lys Ala Lys Val Ser Glu Glu Glu 
        275                 280                 285             


Asn Asp Ile Glu Glu Gln Gln Asp Glu Phe Phe Ser Gly Asp Asn Gly 
    290                 295                 300                 


Val Asp Leu Leu Ile Glu Asp Gln Leu Leu Arg His Asn Gly Leu Met 
305                 310                 315                 320 


Thr Ser Val Thr Arg Arg Pro Ala Ala Thr Arg Gln Gly His Ser Thr 
                325                 330                 335     


Ala Val Thr Ser Asp Leu Asn Ala Arg Thr Ala Pro Trp Ser Ser Ala 
            340                 345                 350         


Leu Pro Gln Pro Ser Thr Ser Asp Pro Ser Ile Ala Asn His Ala Ser 
        355                 360                 365             


Val Gly Pro Thr Leu Gln Thr Thr Ser Val Ser Pro Asp Pro Thr Arg 
    370                 375                 380                 


Glu Ser Val Leu Gln Pro Ser Pro Gln Val Pro Ala Thr Thr Val Ala 
385                 390                 395                 400 


His Thr Ala Thr Gln Gln Pro Ala Ala Pro Ala Pro Pro Ala Val Ser 
                405                 410                 415     


Pro Arg Glu Ala Leu Met Glu Ala Met His Thr Val Pro Val Pro Pro 
            420                 425                 430         


Thr Thr Val Arg Thr Asp Ser Leu Gly Lys Asp Ala Pro Ala Gly Trp 
        435                 440                 445             


Gly Thr Thr Pro Ala Ser Pro Thr Leu Ser Pro Glu Glu Glu Asp Asp 
    450                 455                 460                 


Ile Arg Asn Val Ile Gly Arg Cys Lys Asp Thr Leu Ser Thr Ile Thr 
465                 470                 475                 480 


Gly Pro Thr Thr Gln Asn Thr Tyr Gly Arg Asn Glu Gly Ala Trp Met 
                485                 490                 495     


Lys Asp Pro Leu Ala Lys Asp Glu Arg Ile Tyr Val Thr Asn Tyr Tyr 
            500                 505                 510         


Tyr Gly Asn Thr Leu Val Glu Phe Arg Asn Leu Glu Asn Phe Lys Gln 
        515                 520                 525             


Gly Arg Trp Ser Asn Ser Tyr Lys Leu Pro Tyr Ser Trp Ile Gly Thr 
    530                 535                 540                 


Gly His Val Val Tyr Asn Gly Ala Phe Tyr Tyr Asn Arg Ala Phe Thr 
545                 550                 555                 560 


Arg Asn Ile Ile Lys Tyr Asp Leu Lys Gln Arg Tyr Val Ala Ala Trp 
                565                 570                 575     


Ala Met Leu His Asp Val Ala Tyr Glu Glu Ala Thr Pro Trp Arg Trp 
            580                 585                 590         


Gln Gly His Ser Asp Val Asp Phe Ala Val Asp Glu Asn Gly Leu Trp 
        595                 600                 605             


Leu Ile Tyr Pro Ala Leu Asp Asp Glu Gly Phe Ser Gln Glu Val Ile 
    610                 615                 620                 


Val Leu Ser Lys Leu Asn Ala Ala Asp Leu Ser Thr Gln Lys Glu Thr 
625                 630                 635                 640 


Thr Trp Arg Thr Gly Leu Arg Arg Asn Phe Tyr Gly Asn Cys Phe Val 
                645                 650                 655     


Ile Cys Gly Val Leu Tyr Ala Val Asp Ser Tyr Asn Gln Arg Asn Ala 
            660                 665                 670         


Asn Ile Ser Tyr Ala Phe Asp Thr His Thr Asn Thr Gln Ile Val Pro 
        675                 680                 685             


Arg Leu Leu Phe Glu Asn Glu Tyr Ser Tyr Thr Thr Gln Ile Asp Tyr 
    690                 695                 700                 


Asn Pro Lys Asp Arg Leu Leu Tyr Ala Trp Asp Asn Gly His Gln Val 
705                 710                 715                 720 


Thr Tyr His Val Ile Phe Ala Tyr 
                725             


<210>  2506
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  2506

Leu Asp Val Ser Thr Thr Ile Tyr Asn Arg Cys Lys His Ala Ala Ala 
1               5                   10                  15      


Asn Ser Ser Pro Pro Glu Asn Ser Asn Ile Thr Gly Leu Tyr Ala Thr 
            20                  25                  30          


Ala Asn Pro Val Pro Ser Gln His Pro Cys Phe Lys Pro Trp Ser Tyr 
        35                  40                  45              


Ile Pro Asp Gly 
    50          


<210>  2507
<211>  174
<212>  PRT
<213>  Homo Sapiens

<400>  2507

Gly Phe Gly Arg Thr Gly Leu Val Leu Ala Ala Ala Val Glu Ser Glu 
1               5                   10                  15      


Arg Ser Ala Glu Gln Lys Ala Ile Ile Arg Val Ile Pro Leu Lys Met 
            20                  25                  30          


Asp Pro Thr Gly Lys Leu Asn Leu Thr Leu Glu Gly Val Phe Ala Gly 
        35                  40                  45              


Val Ala Glu Ile Thr Pro Ala Glu Gly Lys Leu Met Gln Ser His Pro 
    50                  55                  60                  


Leu Tyr Leu Cys Asn Ala Ser Asp Asp Asp Asn Leu Glu Pro Gly Phe 
65                  70                  75                  80  


Ile Ser Ile Val Lys Leu Glu Ser Pro Arg Arg Ala Pro Arg Pro Cys 
                85                  90                  95      


Leu Ser Leu Ala Ser Lys Ala Arg Met Ala Gly Glu Arg Gly Ala Ser 
            100                 105                 110         


Ala Val Leu Phe Asp Ile Thr Glu Asp Arg Ala Ala Ala Glu Gln Leu 
        115                 120                 125             


Gln Gln Pro Leu Gly Leu Thr Trp Pro Val Val Leu Ile Trp Gly Asn 
    130                 135                 140                 


Asp Ala Glu Lys Leu Met Glu Phe Val Tyr Lys Asn Gln Lys Ala His 
145                 150                 155                 160 


Val Arg Ile Glu Leu Lys Glu Pro Pro Ala Trp Pro Asp Tyr 
                165                 170                 


<210>  2508
<211>  88
<212>  PRT
<213>  Homo Sapiens

<400>  2508

Gly Phe Arg Ala Thr Gln Arg Tyr Asp Asp Cys Phe Ser Thr Asn Ile 
1               5                   10                  15      


Leu Thr Leu Ile Asn Gly Phe Asp Leu Pro Glu Gly Asn Val Thr Gln 
            20                  25                  30          


Glu Asn Phe Val Asp Met Gln Gln Arg Cys Asn Ala Ser Asp Pro Ala 
        35                  40                  45              


Ala Tyr Ala Gln Leu Val Phe Gln Thr Cys Asp Ile Asn Ala Phe Leu 
    50                  55                  60                  


Ser Glu Ala Val Glu Gly Thr Gly Leu Ala Phe Ile Val Phe Thr Glu 
65                  70                  75                  80  


Ala Ile Thr Lys Met Pro Leu Ser 
                85              


<210>  2509
<211>  455
<212>  PRT
<213>  Homo Sapiens

<400>  2509

Gly Pro Leu Gln Ser Gly Glu Glu Ser Thr Gly Thr Asn Ile Gly Glu 
1               5                   10                  15      


Ala Leu Gly His Gly Leu Gly Asp Ala Leu Ser Glu Gly Val Gly Lys 
            20                  25                  30          


Ala Ile Gly Lys Glu Ala Gly Gly Ala Ala Gly Ser Lys Val Ser Glu 
        35                  40                  45              


Ala Leu Gly Gln Gly Thr Arg Glu Ala Val Gly Thr Gly Val Arg Gln 
    50                  55                  60                  


Val Pro Gly Phe Gly Ala Ala Asp Ala Leu Gly Asn Arg Val Gly Glu 
65                  70                  75                  80  


Ala Ala His Ala Leu Gly Asn Thr Gly His Glu Ile Gly Arg Gln Ala 
                85                  90                  95      


Glu Asp Val Ile Arg His Gly Ala Asp Ala Val Arg Gly Ser Trp Gln 
            100                 105                 110         


Gly Val Pro Gly His Asn Gly Ala Trp Glu Thr Ser Gly Gly His Gly 
        115                 120                 125             


Ile Phe Gly Ser Gln Gly Gly Leu Gly Gly Gln Gly Gln Gly Asn Pro 
    130                 135                 140                 


Gly Gly Leu Gly Thr Pro Trp Val His Gly Tyr Pro Gly Asn Ser Ala 
145                 150                 155                 160 


Gly Ser Phe Gly Met Asn Pro Gln Gly Ala Pro Trp Gly Gln Gly Gly 
                165                 170                 175     


Asn Gly Gly Pro Pro Asn Phe Gly Thr Asn Thr Gln Gly Ala Val Ala 
            180                 185                 190         


Gln Pro Gly Tyr Gly Ser Val Arg Ala Ser Asn Gln Asn Glu Gly Cys 
        195                 200                 205             


Thr Asn Pro Pro Pro Ser Gly Ser Gly Gly Gly Ser Ser Asn Ser Gly 
    210                 215                 220                 


Gly Gly Ser Gly Ser Gln Ser Gly Ser Ser Gly Ser Gly Ser Asn Gly 
225                 230                 235                 240 


Asp Asn Asn Asn Gly Ser Ser Ser Gly Gly Ser Ser Ser Gly Ser Ser 
                245                 250                 255     


Ser Gly Gly Ser Ser Gly Gly Ser Ser Gly Gly Ser Ser Gly Asn Ser 
            260                 265                 270         


Gly Gly Ser Arg Gly Asp Ser Gly Ser Glu Ser Ser Trp Gly Ser Ser 
        275                 280                 285             


Thr Gly Ser Ser Ser Gly Asn His Gly Gly Ser Gly Gly Gly Asn Gly 
    290                 295                 300                 


His Lys Pro Gly Cys Glu Lys Pro Gly Asn Glu Ala Arg Gly Ser Gly 
305                 310                 315                 320 


Glu Ser Gly Ile Gln Asn Ser Glu Thr Ser Pro Gly Met Phe Asn Phe 
                325                 330                 335     


Asp Thr Phe Trp Lys Asn Phe Lys Ser Lys Leu Gly Phe Ile Asn Trp 
            340                 345                 350         


Asp Ala Ile Asn Lys Asn Gln Val Pro Pro Pro Ser Thr Arg Ala Leu 
        355                 360                 365             


Leu Tyr Phe Ser Arg Leu Trp Glu Asp Phe Lys Gln Asn Thr Pro Phe 
    370                 375                 380                 


Leu Asn Trp Lys Ala Ile Ile Glu Gly Ala Asp Ala Ser Ser Leu Gln 
385                 390                 395                 400 


Lys Arg Ala Gly Arg Ala Asp Gln Asn Tyr Asn Tyr Asn Gln His Ala 
                405                 410                 415     


Tyr Pro Thr Ala Tyr Gly Gly Lys Tyr Ser Val Lys Thr Pro Ala Lys 
            420                 425                 430         


Gly Gly Val Ser Pro Ser Ser Ser Ala Ser Arg Val Gln Pro Gly Leu 
        435                 440                 445             


Leu Gln Trp Val Lys Phe Trp 
    450                 455 


<210>  2510
<211>  328
<212>  PRT
<213>  Homo Sapiens

<400>  2510

Val Arg Gly Ala Pro Cys Glu Ala Val Arg Ile Pro Met Cys Arg His 
1               5                   10                  15      


Met Pro Trp Asn Ile Thr Arg Met Pro Asn His Leu His His Ser Thr 
            20                  25                  30          


Gln Glu Asn Ala Ile Leu Ala Ile Glu Gln Tyr Glu Glu Leu Val Asp 
        35                  40                  45              


Val Asn Cys Ser Ala Val Leu Arg Phe Phe Leu Cys Ala Met Tyr Ala 
    50                  55                  60                  


Pro Ile Cys Thr Leu Glu Phe Leu His Asp Pro Ile Lys Pro Cys Lys 
65                  70                  75                  80  


Ser Val Cys Gln Arg Ala Arg Asp Asp Cys Glu Pro Leu Met Lys Met 
                85                  90                  95      


Tyr Asn His Ser Trp Pro Glu Ser Leu Ala Cys Asp Glu Leu Pro Val 
            100                 105                 110         


Tyr Asp Arg Gly Val Cys Ile Ser Pro Glu Ala Ile Val Thr Asp Leu 
        115                 120                 125             


Pro Glu Asp Val Lys Trp Ile Asp Ile Thr Pro Asp Met Met Val Gln 
    130                 135                 140                 


Glu Arg Pro Leu Asp Val Asp Cys Lys Arg Leu Ser Pro Asp Arg Cys 
145                 150                 155                 160 


Lys Cys Lys Lys Val Lys Pro Thr Leu Ala Thr Tyr Leu Ser Lys Asn 
                165                 170                 175     


Tyr Ser Tyr Val Ile His Ala Lys Ile Lys Ala Val Gln Arg Ser Gly 
            180                 185                 190         


Cys Asn Glu Val Thr Thr Val Val Asp Val Lys Glu Ile Phe Lys Ser 
        195                 200                 205             


Ser Ser Pro Ile Pro Arg Thr Gln Val Pro Leu Ile Thr Asn Ser Ser 
    210                 215                 220                 


Cys Gln Cys Pro His Ile Leu Pro His Gln Asp Val Leu Ile Met Cys 
225                 230                 235                 240 


Tyr Glu Trp Arg Ser Arg Met Met Leu Leu Glu Asn Cys Leu Val Glu 
                245                 250                 255     


Lys Trp Arg Asp Gln Leu Ser Lys Arg Ser Ile Gln Trp Glu Glu Arg 
            260                 265                 270         


Leu Gln Glu Gln Arg Arg Thr Val Gln Asp Lys Lys Lys Thr Ala Gly 
        275                 280                 285             


Arg Thr Ser Arg Ser Asn Pro Pro Lys Pro Lys Gly Lys Pro Pro Ala 
    290                 295                 300                 


Pro Lys Pro Ala Ser Pro Lys Lys Asn Ile Lys Thr Arg Ser Ala Gln 
305                 310                 315                 320 


Lys Arg Thr Asn Pro Lys Arg Val 
                325             


<210>  2511
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  2511

Cys Gly Val Pro Ala Ile His Pro Val Leu Ser Gly Leu Ser Arg Ile 
1               5                   10                  15      


Val Asn Gly Glu Asp Ala Val Pro Gly Ser Trp Pro Trp Gln Val Ser 
            20                  25                  30          


Leu Gln Asp Lys Thr Gly Phe His Phe Cys Gly Gly Ser Leu Ile Ser 
        35                  40                  45              


Glu Asp Trp Val Val Thr Ala Ala His Cys Gly Val Arg Thr Ser Asp 
    50                  55                  60                  


Val Val Val Ala Gly Glu Phe Asp Gln Gly Ser Asp Glu Glu Asn Ile 
65                  70                  75                  80  


Gln Val Leu Lys Ile Ala Lys Val Phe Lys Asn Pro Lys Phe Ser Ile 
                85                  90                  95      


Leu Thr Val Asn Asn Asp Ile Thr Leu Leu Lys Leu Ala Thr Pro Ala 
            100                 105                 110         


Arg Phe Ser Gln Thr Val Ser Ala Val Cys Leu Pro Ser Ala Asp Asp 
        115                 120                 125             


Asp Phe Pro Ala Gly Thr Leu Cys Ala Thr Thr Gly Trp Gly Lys Thr 
    130                 135                 140                 


Lys Tyr Asn Ala Asn Lys Thr Pro Asp Lys Leu Gln Gln Ala Ala Leu 
145                 150                 155                 160 


Pro Leu Leu Ser Asn Ala Glu Cys Lys Lys Ser Trp Gly Arg Arg Ile 
                165                 170                 175     


Thr Asp Val Met Ile Cys Ala Gly Ala Ser Gly Val Ser Ser Cys Met 
            180                 185                 190         


Gly Asp Ser Gly Gly Pro Leu Val Cys Gln Lys Asp Gly Ala Trp Thr 
        195                 200                 205             


Leu Val Gly Ile Val Ser Trp Gly Ser Arg Thr Cys Ser Thr Thr Thr 
    210                 215                 220                 


Pro Ala Val Tyr Ala Arg Val Thr Lys Leu Ile Pro Trp Val Gln Lys 
225                 230                 235                 240 


Ile Leu Ala Ala Asn 
                245 


<210>  2512
<211>  545
<212>  PRT
<213>  Homo Sapiens

<400>  2512

Leu Pro Val Lys Lys Pro Arg Leu Arg Gly Pro Arg Pro Gly Ser Leu 
1               5                   10                  15      


Thr Arg Leu Ala Glu Val Ser Ala Ser Pro Asp Pro Arg Pro Leu Lys 
            20                  25                  30          


Glu Glu Glu Glu Ala Pro Leu Leu Pro Arg Thr His Leu Gln Ala Glu 
        35                  40                  45              


Pro His Gln His Gly Cys Trp Thr Val Thr Glu Pro Ala Ala Met Thr 
    50                  55                  60                  


Pro Gly Asn Thr Thr Pro Pro Arg Thr Pro Glu Val Thr Pro Leu Arg 
65                  70                  75                  80  


Leu Glu Leu Gln Lys Leu Pro Gly Leu Ala Asn Thr Thr Leu Ser Thr 
                85                  90                  95      


Pro Asn Pro Asp Thr Gln Ala Ser Ala Ser Pro Asp Pro Arg Pro Leu 
            100                 105                 110         


Arg Glu Glu Glu Glu Ala Arg Leu Leu Pro Arg Thr His Leu Gln Ala 
        115                 120                 125             


Glu Leu His Gln His Gly Cys Trp Thr Val Thr Glu Pro Ala Ala Leu 
    130                 135                 140                 


Thr Pro Gly Asn Ala Thr Pro Pro Arg Thr Gln Glu Val Thr Pro Leu 
145                 150                 155                 160 


Leu Leu Glu Leu Gln Lys Leu Pro Glu Leu Val His Ala Thr Leu Ser 
                165                 170                 175     


Thr Pro Asn Pro Asp Asn Gln Val Thr Ile Lys Val Val Glu Asp Pro 
            180                 185                 190         


Gln Ala Glu Val Ser Ile Asp Leu Leu Ala Glu Pro Ser Asn Pro Pro 
        195                 200                 205             


Pro Gln Asp Thr Leu Ser Trp Leu Pro Ala Leu Trp Ser Phe Leu Trp 
    210                 215                 220                 


Gly Asp Tyr Lys Gly Glu Glu Lys Asp Arg Ala Pro Gly Glu Lys Gly 
225                 230                 235                 240 


Glu Glu Lys Glu Glu Asp Glu Asp Tyr Pro Ser Glu Asp Ile Glu Gly 
                245                 250                 255     


Glu Asp Gln Glu Asp Lys Glu Glu Asp Glu Glu Glu Gln Ala Leu Trp 
            260                 265                 270         


Phe Asn Gly Thr Thr Asp Asn Trp Asp Gln Gly Trp Leu Ala Pro Gly 
        275                 280                 285             


Asp Trp Val Phe Lys Asp Ser Val Ser Tyr Asp Tyr Glu Pro Gln Lys 
    290                 295                 300                 


Glu Trp Ser Pro Trp Ser Pro Cys Ser Gly Asn Cys Ser Thr Gly Lys 
305                 310                 315                 320 


Gln Gln Arg Thr Arg Pro Cys Gly Tyr Gly Cys Thr Ala Thr Glu Thr 
                325                 330                 335     


Arg Thr Cys Asp Leu Pro Ser Cys Pro Gly Thr Glu Asp Lys Asp Thr 
            340                 345                 350         


Leu Gly Leu Pro Ser Glu Glu Trp Lys Leu Leu Ala Arg Asn Ala Thr 
        355                 360                 365             


Asp Met His Asp Gln Asp Val Asp Ser Cys Glu Lys Trp Leu Asn Cys 
    370                 375                 380                 


Lys Ser Asp Phe Leu Ile Lys Tyr Leu Ser Gln Met Leu Arg Asp Leu 
385                 390                 395                 400 


Pro Ser Cys Pro Cys Ala Tyr Pro Leu Glu Ala Met Asp Ser Pro Val 
                405                 410                 415     


Ser Leu Gln Asp Glu His Gln Gly Arg Ser Phe Arg Trp Arg Asp Ala 
            420                 425                 430         


Ser Gly Pro Arg Glu Arg Leu Asp Ile Tyr Gln Pro Thr Ala Arg Phe 
        435                 440                 445             


Cys Leu Arg Ser Met Leu Ser Gly Glu Ser Ser Thr Leu Ala Ala Gln 
    450                 455                 460                 


His Cys Cys Tyr Asp Glu Asp Ser Arg Leu Leu Thr Arg Gly Lys Gly 
465                 470                 475                 480 


Ala Gly Met Pro Asn Leu Ile Ser Thr Asp Phe Ser Pro Lys Leu His 
                485                 490                 495     


Phe Lys Phe Asp Thr Thr Pro Trp Ile Leu Cys Lys Gly Asp Trp Ser 
            500                 505                 510         


Arg Leu His Ala Val Leu Pro Pro Asn Asn Gly Arg Ala Cys Thr Asp 
        515                 520                 525             


Asn Pro Leu Glu Glu Glu Tyr Leu Ala Gln Leu Gln Glu Ala Lys Glu 
    530                 535                 540                 


Tyr 
545 


<210>  2513
<211>  408
<212>  PRT
<213>  Homo Sapiens

<400>  2513

Ala Pro Leu Ala Ser Ser Cys Ala Gly Ala Cys Gly Thr Ser Phe Pro 
1               5                   10                  15      


Asp Gly Leu Thr Pro Glu Gly Thr Gln Ala Ser Gly Asp Lys Asp Ile 
            20                  25                  30          


Pro Ala Ile Asn Gln Gly Leu Ile Leu Glu Glu Thr Pro Glu Ser Ser 
        35                  40                  45              


Phe Leu Ile Glu Gly Asp Ile Ile Arg Pro Ser Pro Phe Arg Leu Leu 
    50                  55                  60                  


Ser Ala Thr Ser Asn Lys Trp Pro Met Gly Gly Ser Gly Val Val Glu 
65                  70                  75                  80  


Val Pro Phe Leu Leu Ser Ser Lys Tyr Asp Glu Pro Ser Arg Gln Val 
                85                  90                  95      


Ile Leu Glu Ala Leu Ala Glu Phe Glu Arg Ser Thr Cys Ile Arg Phe 
            100                 105                 110         


Val Thr Tyr Gln Asp Gln Arg Asp Phe Ile Ser Ile Ile Pro Met Tyr 
        115                 120                 125             


Gly Cys Phe Ser Ser Val Gly Arg Ser Gly Gly Met Gln Val Val Ser 
    130                 135                 140                 


Leu Ala Pro Thr Cys Leu Gln Lys Gly Arg Gly Ile Val Leu His Glu 
145                 150                 155                 160 


Leu Met His Val Leu Gly Phe Trp His Glu His Thr Arg Ala Asp Arg 
                165                 170                 175     


Asp Arg Tyr Ile Arg Val Asn Trp Asn Glu Ile Leu Pro Gly Phe Glu 
            180                 185                 190         


Ile Asn Phe Ile Lys Ser Arg Ser Ser Asn Met Leu Thr Pro Tyr Asp 
        195                 200                 205             


Tyr Ser Ser Val Met His Tyr Gly Arg Leu Ala Phe Ser Arg Arg Gly 
    210                 215                 220                 


Leu Pro Thr Ile Thr Pro Leu Trp Ala Pro Ser Val His Ile Gly Gln 
225                 230                 235                 240 


Arg Trp Asn Leu Ser Ala Ser Asp Ile Thr Arg Val Leu Gln Leu Tyr 
                245                 250                 255     


Gly Cys Ser Pro Ser Gly Pro Arg Pro Arg Gly Arg Gly Ser His Ala 
            260                 265                 270         


His Ser Thr Gly Arg Ser Pro Ala Pro Ala Ser Leu Ser Leu Gln Arg 
        275                 280                 285             


Leu Leu Glu Ala Leu Ser Ala Glu Ser Arg Ser Pro Asp Pro Ser Gly 
    290                 295                 300                 


Ser Ser Ala Gly Gly Gln Pro Val Pro Ala Gly Pro Gly Glu Ser Pro 
305                 310                 315                 320 


His Gly Trp Glu Ser Pro Ala Leu Lys Lys Leu Ser Ala Glu Ala Ser 
                325                 330                 335     


Ala Arg Gln Pro Gln Thr Leu Ala Ser Ser Pro Arg Ser Arg Pro Gly 
            340                 345                 350         


Ala Gly Ala Pro Gly Val Ala Gln Glu Gln Ser Trp Leu Ala Gly Val 
        355                 360                 365             


Ser Thr Lys Pro Thr Val Pro Ser Ser Glu Ala Gly Ile Gln Pro Val 
    370                 375                 380                 


Pro Val Gln Gly Ser Pro Ala Leu Pro Gly Gly Cys Val Pro Arg Asn 
385                 390                 395                 400 


His Phe Lys Gly Met Ser Glu Asp 
                405             


<210>  2514
<211>  76
<212>  PRT
<213>  Homo Sapiens

<400>  2514

Ser Val Ser Gly Pro Arg His Trp Trp Pro Pro Arg Gly Ile Ile Lys 
1               5                   10                  15      


Val Lys Cys Pro Tyr Glu Lys Val Asn Leu Ser Trp Tyr Asn Gly Thr 
            20                  25                  30          


Val Asn Pro Cys Pro Gly Leu Tyr Gln Pro Ile Cys Gly Thr Asn Phe 
        35                  40                  45              


Ile Thr Tyr Asp Asn Pro Cys Ile Leu Cys Val Glu Ser Leu Lys Ser 
    50                  55                  60                  


His Gly Arg Ile Arg Phe Tyr His Asp Gly Lys Cys 
65                  70                  75      


<210>  2515
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2515

Thr Pro Phe Pro Ser Leu Ala Pro Pro Ile Met Leu Leu Val Asp Gly 
1               5                   10                  15      


Lys Gln Gln Met Val Val Val Cys Leu Val Leu Asp Val Ala Pro Pro 
            20                  25                  30          


Gly Leu Asp Ser Pro Ile Trp Phe Ser Ala Gly Asn Gly Ser Ala Leu 
        35                  40                  45              


Asp Ala Phe Thr Tyr Gly Pro Ser Pro Ala Thr Asp Gly Thr Trp Thr 
    50                  55                  60                  


Asn Leu Ala His Leu Ser Leu Pro Ser Glu Glu Leu Ala Ser Trp Glu 
65                  70                  75                  80  


Pro Leu Val Cys His Thr Gly Pro Gly Ala Glu Gly His Ser Arg Ser 
                85                  90                  95      


Thr Gln Pro Met His Leu Ser Gly Glu Ala Ser Thr Ala Arg Thr Cys 
            100                 105                 110         


Pro Gln Glu Pro Leu Arg Gly Thr Pro Gly Gly 
        115                 120             


<210>  2516
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  2516

Thr Arg Gly Ser Ser Thr Gly Ala His Ile Ser Pro Gln Phe Pro Ala 
1               5                   10                  15      


Ser Gly Val Asn Gln Thr Pro Val Val Asp Cys Arg Lys Val Cys Gly 
            20                  25                  30          


Leu Asn Val Ser Asp Arg Cys Asp Phe Ile Arg Thr Asn Pro Asp Cys 
        35                  40                  45              


His Ser Asp Gly Gly Tyr Leu Asp Tyr Leu Glu Gly Ile Phe Cys His 
    50                  55                  60                  


Phe Pro Pro Ser Leu 
65                  


<210>  2517
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  2517

Arg Lys Arg Arg Phe Pro Phe Ile Gly Glu Asp Asp Asn Asp Asp Gly 
1               5                   10                  15      


His Pro Leu His Pro Ser Leu Asn Ile Pro Tyr Gly Ile Arg Asn Leu 
            20                  25                  30          


Pro Pro Pro Leu Tyr Tyr Arg Pro Val Asn Thr Val Pro Ser Tyr Pro 
        35                  40                  45              


Gly Asn Thr Tyr Thr Asp Thr Gly Leu Pro Ser Tyr Pro Trp Ile Leu 
    50                  55                  60                  


Thr Ser Pro Gly Phe Pro Tyr Val Tyr His Ile Arg Gly Phe Pro Leu 
65                  70                  75                  80  


Ala Thr Gln Leu Asn Val Pro Pro Leu Pro Pro Arg Gly Phe Pro Phe 
                85                  90                  95      


Val Pro Pro Ser Arg Phe Phe Ser Ala Ala Ala Ala Pro Ala Ala Pro 
            100                 105                 110         


Pro Ile Ala Ala Glu Pro Ala Ala Ala Ala Pro Leu Thr Ala Thr Pro 
        115                 120                 125             


Val Ala Ala Glu Pro Ala Ala Gly Ala Pro Val Ala Ala Glu Pro Ala 
    130                 135                 140                 


Ala Glu Ala Pro Val Gly Ala Glu Pro Ala Ala Glu Ala Pro Val Ala 
145                 150                 155                 160 


Ala Glu Pro Ala Ala Glu Ala Pro Val Gly Val Glu Pro Ala Ala Glu 
                165                 170                 175     


Glu Pro Ser Pro Ala Glu Pro Ala Thr Ala Lys Pro Ala Ala Pro Glu 
            180                 185                 190         


Pro His Pro Ser Pro Ser Leu Glu Gln Ala Asn Gln 
        195                 200                 


<210>  2518
<211>  637
<212>  PRT
<213>  Homo Sapiens

<400>  2518

Tyr Ser Val Ser Leu Arg Lys Ala Glu Arg Leu Arg Ala Glu Leu Leu 
1               5                   10                  15      


Asp Leu Lys Ala Gly Gly Phe Ser Ile Arg Asn Gln Lys Gly Glu Gln 
            20                  25                  30          


Val Phe Arg Leu Ala Phe Arg Ser Gly Ala Leu Asp Leu Asp Ser Cys 
        35                  40                  45              


Ser Arg Asp Gly Ala Leu Leu Gly Cys Ser Leu Thr Ala Asp Gly Leu 
    50                  55                  60                  


Pro Leu His Phe Phe Ile Gln Thr Val Arg Pro Lys Asp Thr Val Met 
65                  70                  75                  80  


Cys Tyr Arg Val Arg Trp Glu Glu Ala Ala Pro Gly Arg Ala Val Glu 
                85                  90                  95      


His Ala Met Phe Leu Gly Asp Ala Ala Ala His Trp Tyr Gly Gly Ala 
            100                 105                 110         


Glu Met Arg Thr Gln His Trp Pro Ile Arg Leu Asp Gly Gln Gln Glu 
        115                 120                 125             


Pro Gln Pro Phe Val Thr Ser Asp Val Tyr Ser Ser Asp Ala Ala Phe 
    130                 135                 140                 


Gly Gly Ile Leu Glu Arg Tyr Trp Leu Ser Ser Arg Ala Ala Ala Ile 
145                 150                 155                 160 


Lys Val Asn Asp Ser Val Pro Phe His Leu Gly Trp Asn Ser Thr Glu 
                165                 170                 175     


Arg Ser Leu Arg Leu Gln Ala Arg Tyr His Asp Thr Pro Tyr Lys Pro 
            180                 185                 190         


Pro Ala Gly Arg Ala Ala Ala Pro Glu Leu Ser Tyr Arg Val Cys Val 
        195                 200                 205             


Gly Ser Asp Val Thr Ser Ile His Lys Tyr Met Val Arg Arg Tyr Phe 
    210                 215                 220                 


Asn Lys Pro Ser Arg Val Pro Ala Pro Glu Ala Phe Arg Asp Pro Ile 
225                 230                 235                 240 


Trp Ser Thr Trp Ala Leu Tyr Gly Arg Ala Val Asp Gln Asp Lys Val 
                245                 250                 255     


Leu Arg Phe Ala Gln Gln Ile Arg Leu His His Phe Asn Ser Ser His 
            260                 265                 270         


Leu Glu Ile Asp Asp Met Tyr Thr Pro Ala Tyr Gly Asp Phe Asp Phe 
        275                 280                 285             


Asp Glu Val Lys Phe Pro Asn Ala Ser Asp Met Phe Arg Arg Leu Arg 
    290                 295                 300                 


Asp Ala Gly Phe Arg Val Thr Leu Trp Val His Pro Phe Val Asn Tyr 
305                 310                 315                 320 


Asn Ser Ser Arg Phe Gly Glu Gly Val Glu Arg Glu Leu Phe Val Arg 
                325                 330                 335     


Glu Pro Thr Gly Arg Leu Pro Ala Leu Val Arg Trp Trp Asn Gly Ile 
            340                 345                 350         


Gly Ala Val Leu Asp Phe Thr His Pro Lys Ala Arg Asp Trp Phe Gln 
        355                 360                 365             


Gly His Leu Arg Arg Leu Arg Ser Arg Tyr Ser Val Ala Ser Phe Lys 
    370                 375                 380                 


Phe Asp Ala Gly Glu Val Ser Tyr Leu Pro Arg Asp Phe Ser Thr Tyr 
385                 390                 395                 400 


Arg Pro Leu Pro Asp Pro Ser Val Trp Ser Arg Arg Tyr Thr Glu Met 
                405                 410                 415     


Ala Leu Pro Phe Phe Ser Leu Ala Glu Val Arg Val Gly Tyr Gln Ser 
            420                 425                 430         


Gln Asn Ile Ser Cys Phe Phe Arg Leu Val Asp Arg Asp Ser Val Trp 
        435                 440                 445             


Gly Tyr Asp Leu Gly Leu Arg Ser Leu Ile Pro Ala Val Leu Thr Val 
    450                 455                 460                 


Ser Met Leu Gly Tyr Pro Phe Ile Leu Pro Asp Met Val Gly Gly Asn 
465                 470                 475                 480 


Ala Val Pro Gln Arg Thr Ala Gly Gly Asp Val Pro Glu Arg Glu Leu 
                485                 490                 495     


Tyr Ile Arg Trp Leu Glu Val Ala Ala Phe Met Pro Ala Met Gln Phe 
            500                 505                 510         


Ser Ile Pro Pro Trp Arg Tyr Asp Ala Glu Val Val Ala Ile Ala Gln 
        515                 520                 525             


Lys Phe Ala Ala Leu Arg Ala Ser Leu Val Ala Pro Leu Leu Leu Glu 
    530                 535                 540                 


Leu Ala Gly Glu Val Thr Asp Thr Gly Asp Pro Ile Val Arg Pro Leu 
545                 550                 555                 560 


Trp Trp Ile Ala Pro Gly Asp Glu Thr Ala His Arg Ile Asp Ser Gln 
                565                 570                 575     


Phe Leu Ile Gly Asp Thr Leu Leu Val Ala Pro Val Leu Glu Pro Gly 
            580                 585                 590         


Lys Gln Glu Arg Asp Val Tyr Leu Pro Ala Gly Lys Trp Arg Ser Tyr 
        595                 600                 605             


Lys Gly Glu Leu Phe Asp Lys Thr Pro Val Leu Leu Thr Asp Tyr Pro 
    610                 615                 620                 


Val Asp Leu Asp Glu Ile Ala Tyr Phe Thr Trp Ala Ser 
625                 630                 635         


<210>  2519
<211>  201
<212>  PRT
<213>  Homo Sapiens

<400>  2519

Ser Pro Ser Ile Arg Gln Lys Lys Leu Met His Lys Leu Gln Glu Glu 
1               5                   10                  15      


Lys Ala Phe Arg Glu Glu Met Lys Ile Phe Arg Glu Lys Ile Glu Asp 
            20                  25                  30          


Phe Arg Glu Glu Met Trp Thr Phe Arg Gly Lys Ile His Ala Phe Arg 
        35                  40                  45              


Gly Gln Ile Leu Gly Phe Trp Glu Glu Glu Arg Pro Phe Trp Glu Glu 
    50                  55                  60                  


Glu Lys Thr Phe Trp Lys Glu Glu Lys Ser Phe Trp Glu Met Glu Lys 
65                  70                  75                  80  


Ser Phe Arg Glu Glu Glu Lys Thr Phe Trp Lys Lys Tyr Arg Thr Phe 
                85                  90                  95      


Trp Lys Glu Asp Lys Ala Phe Trp Lys Glu Asp Asn Ala Leu Trp Glu 
            100                 105                 110         


Arg Asp Arg Asn Leu Leu Gln Glu Asp Lys Ala Leu Trp Glu Glu Glu 
        115                 120                 125             


Lys Ala Leu Trp Val Glu Glu Arg Ala Leu Leu Glu Gly Glu Lys Ala 
    130                 135                 140                 


Leu Trp Glu Asp Lys Thr Ser Leu Trp Glu Glu Glu Asn Ala Leu Trp 
145                 150                 155                 160 


Glu Glu Glu Arg Ala Phe Trp Met Glu Asn Asn Gly His Val Ala Gly 
                165                 170                 175     


Glu Gln Met Leu Glu Asp Gly Pro His Asn Ala Asn Arg Gly Gln Arg 
            180                 185                 190         


Leu Leu Ala Phe Ser Arg Gly Arg Ala 
        195                 200     


<210>  2520
<211>  592
<212>  PRT
<213>  Homo Sapiens

<400>  2520

Lys Val Tyr Leu Gly Leu Phe Ser Gly Ser Ser Pro Asn Pro Phe Ser 
1               5                   10                  15      


Glu Asp Val Lys Arg Pro Pro Ala Pro Leu Val Thr Asp Lys Glu Ala 
            20                  25                  30          


Arg Lys Lys Val Leu Lys Gln Ala Phe Ser Ala Asn Gln Val Pro Glu 
        35                  40                  45              


Lys Leu Asp Val Val Val Ile Gly Ser Gly Phe Gly Gly Leu Ala Ala 
    50                  55                  60                  


Ala Ala Ile Leu Ala Lys Ala Gly Lys Arg Val Leu Val Leu Glu Gln 
65                  70                  75                  80  


His Thr Lys Ala Gly Gly Cys Cys His Thr Phe Gly Lys Asn Gly Pro 
                85                  90                  95      


Glu Phe Asp Thr Gly Ile His Tyr Ile Gly Arg Met Glu Glu Gly Ser 
            100                 105                 110         


Ile Gly Arg Phe Ile Leu Asp Gln Ile Thr Glu Gly Gln Leu Asp Trp 
        115                 120                 125             


Ala Pro Leu Ser Ser Pro Phe Asp Ile Met Val Leu Glu Gly Pro Asn 
    130                 135                 140                 


Gly Arg Lys Glu Tyr Pro Met Tyr Ser Gly Glu Lys Ala Tyr Ile Gln 
145                 150                 155                 160 


Gly Leu Lys Glu Lys Phe Pro Gln Glu Glu Ala Ile Ile Asp Lys Tyr 
                165                 170                 175     


Ile Lys Leu Val Lys Val Val Ser Ser Gly Ala Pro His Ala Ile Leu 
            180                 185                 190         


Leu Lys Phe Leu Pro Leu Pro Val Val Gln Leu Leu Asp Arg Cys Gly 
        195                 200                 205             


Leu Leu Thr Arg Phe Ser Pro Phe Leu Gln Ala Ser Thr Gln Ser Leu 
    210                 215                 220                 


Ala Glu Val Leu Gln Gln Leu Gly Ala Ser Ser Glu Leu Gln Ala Val 
225                 230                 235                 240 


Leu Ser Tyr Ile Phe Pro Thr Tyr Gly Val Thr Pro Asn His Ser Ala 
                245                 250                 255     


Phe Ser Met His Ala Leu Leu Val Asn His Tyr Met Lys Gly Gly Phe 
            260                 265                 270         


Tyr Pro Arg Gly Gly Ser Ser Glu Ile Ala Phe His Thr Ile Pro Val 
        275                 280                 285             


Ile Gln Arg Ala Gly Gly Ala Val Leu Thr Lys Ala Thr Val Gln Ser 
    290                 295                 300                 


Val Leu Leu Asp Ser Ala Gly Lys Ala Cys Gly Val Ser Val Lys Lys 
305                 310                 315                 320 


Gly His Glu Leu Val Asn Ile Tyr Cys Pro Ile Val Val Ser Asn Ala 
                325                 330                 335     


Gly Leu Phe Asn Thr Tyr Glu His Leu Leu Pro Gly Asn Ala Arg Cys 
            340                 345                 350         


Leu Pro Gly Val Lys Gln Gln Leu Gly Thr Val Arg Pro Gly Leu Gly 
        355                 360                 365             


Met Thr Ser Val Phe Ile Cys Leu Arg Gly Thr Arg Glu Asp Leu His 
    370                 375                 380                 


Leu Pro Ser Thr Asn Tyr Tyr Val Tyr Tyr Asp Thr Asp Met Asp Gln 
385                 390                 395                 400 


Ala Met Glu Arg Tyr Val Ser Met Pro Arg Glu Glu Ala Ala Glu His 
                405                 410                 415     


Ile Pro Leu Leu Phe Phe Ala Phe Pro Ser Ala Lys Asp Pro Thr Trp 
            420                 425                 430         


Glu Asp Arg Phe Pro Gly Arg Ser Thr Met Ile Met Leu Ile Pro Thr 
        435                 440                 445             


Ala Tyr Glu Trp Phe Glu Glu Trp Gln Ala Glu Leu Lys Gly Lys Arg 
    450                 455                 460                 


Gly Ser Asp Tyr Glu Thr Phe Lys Asn Ser Phe Val Glu Ala Ser Met 
465                 470                 475                 480 


Ser Val Val Leu Lys Leu Phe Pro Gln Leu Glu Gly Lys Val Glu Ser 
                485                 490                 495     


Val Thr Ala Gly Ser Pro Leu Thr Asn Gln Phe Tyr Leu Ala Ala Pro 
            500                 505                 510         


Arg Gly Ala Cys Tyr Gly Ala Asp His Asp Leu Gly Arg Leu His Pro 
        515                 520                 525             


Cys Val Met Ala Ser Leu Arg Ala Gln Ser Pro Ile Pro Asn Leu Tyr 
    530                 535                 540                 


Leu Thr Gly Gln Asp Ile Phe Thr Cys Gly Leu Val Gly Ala Leu Gln 
545                 550                 555                 560 


Gly Ala Leu Leu Cys Ser Ser Ala Ile Leu Lys Arg Asn Leu Tyr Ser 
                565                 570                 575     


Asp Leu Lys Asn Leu Asp Ser Arg Ile Arg Ala Gln Lys Lys Lys Asn 
            580                 585                 590         


<210>  2521
<211>  559
<212>  PRT
<213>  Homo Sapiens

<400>  2521

Gln Pro Ser Ser Ser Pro Ser Gly Ala Val Pro Thr Ser Leu Glu Leu 
1               5                   10                  15      


Gln Arg Gly Thr Asp Gly Gly Thr Leu Gln Ser Pro Ser Glu Ala Thr 
            20                  25                  30          


Ala Thr Arg Pro Ala Val Pro Gly Leu Pro Thr Val Val Pro Thr Leu 
        35                  40                  45              


Val Thr Pro Ser Ala Pro Gly Asn Arg Thr Val Asp Leu Phe Pro Val 
    50                  55                  60                  


Leu Pro Ile Cys Val Cys Asp Leu Thr Pro Gly Ala Cys Asp Ile Asn 
65                  70                  75                  80  


Cys Cys Cys Asp Arg Asp Cys Tyr Leu Leu His Pro Arg Thr Val Phe 
                85                  90                  95      


Ser Phe Cys Leu Pro Gly Ser Val Arg Ser Ser Ser Trp Val Cys Val 
            100                 105                 110         


Asp Asn Ser Val Ile Phe Arg Ser Asn Ser Pro Phe Pro Ser Arg Val 
        115                 120                 125             


Phe Met Asp Ser Asn Gly Ile Arg Gln Phe Cys Val His Val Asn Asn 
    130                 135                 140                 


Ser Asn Leu Asn Tyr Phe Gln Lys Leu Gln Lys Val Asn Ala Thr Asn 
145                 150                 155                 160 


Phe Gln Ala Leu Ala Ala Glu Phe Gly Gly Glu Ser Phe Thr Ser Thr 
                165                 170                 175     


Phe Gln Thr Gln Ser Pro Pro Ser Phe Tyr Arg Ala Gly Asp Pro Ile 
            180                 185                 190         


Leu Thr Tyr Phe Pro Lys Trp Ser Val Ile Ser Leu Leu Arg Gln Pro 
        195                 200                 205             


Ala Gly Val Gly Ala Gly Gly Leu Cys Ala Glu Ser Asn Pro Ala Gly 
    210                 215                 220                 


Phe Leu Glu Ser Lys Ser Thr Thr Cys Thr Arg Phe Phe Lys Asn Leu 
225                 230                 235                 240 


Ala Ser Ser Cys Thr Leu Asp Ser Ala Leu Asn Ala Ala Ser Tyr Tyr 
                245                 250                 255     


Asn Phe Thr Val Leu Lys Val Pro Arg Ser Met Thr Asp Pro Gln Asn 
            260                 265                 270         


Met Glu Phe Gln Val Pro Val Ile Leu Thr Ser Gln Ala Asn Ala Pro 
        275                 280                 285             


Leu Leu Ala Gly Asn Thr Cys Gln Asn Val Val Ser Gln Val Thr Tyr 
    290                 295                 300                 


Glu Ile Glu Thr Asn Gly Thr Phe Gly Ile Gln Lys Val Ser Val Ser 
305                 310                 315                 320 


Leu Gly Gln Thr Asn Leu Thr Val Glu Pro Gly Ala Ser Leu Gln Gln 
                325                 330                 335     


His Phe Ile Leu Arg Phe Arg Ala Phe Gln Gln Ser Thr Ala Ala Ser 
            340                 345                 350         


Leu Thr Ser Pro Arg Ser Gly Asn Pro Gly Tyr Ile Val Gly Lys Pro 
        355                 360                 365             


Leu Leu Ala Leu Thr Asp Asp Ile Ser Tyr Ser Met Thr Leu Leu Gln 
    370                 375                 380                 


Ser Gln Gly Asn Gly Ser Cys Ser Val Lys Arg His Glu Val Gln Phe 
385                 390                 395                 400 


Gly Val Asn Ala Ile Ser Gly Cys Lys Leu Arg Leu Lys Lys Ala Asp 
                405                 410                 415     


Cys Ser His Leu Gln Gln Glu Ile Tyr Gln Thr Leu His Gly Arg Pro 
            420                 425                 430         


Arg Pro Glu Tyr Val Ala Ile Phe Gly Asn Ala Asp Pro Ala Gln Lys 
        435                 440                 445             


Gly Gly Trp Thr Arg Ile Leu Asn Arg His Cys Ser Ile Ser Ala Ile 
    450                 455                 460                 


Asn Cys Thr Ser Cys Cys Leu Ile Pro Val Ser Leu Glu Ile Gln Val 
465                 470                 475                 480 


Leu Trp Ala Tyr Val Gly Leu Leu Ser Asn Pro Gln Ala His Val Ser 
                485                 490                 495     


Gly Val Arg Phe Leu Tyr Gln Cys Gln Ser Ile Gln Asp Ser Gln Gln 
            500                 505                 510         


Val Thr Glu Val Ser Leu Thr Thr Leu Val Asn Phe Val Asp Ile Thr 
        515                 520                 525             


Gln Lys Pro Gln Pro Pro Arg Gly Gln Pro Lys Met Asp Trp Lys Trp 
    530                 535                 540                 


Pro Phe Asp Phe Phe Pro Phe Lys Val Ala Phe Ser Arg Gly Val 
545                 550                 555                 


<210>  2522
<211>  461
<212>  PRT
<213>  Homo Sapiens

<400>  2522

Ala Lys Ile Leu Thr Ile Ser Thr Leu Gly Gly Ser His Tyr Leu Leu 
1               5                   10                  15      


Leu Asp Arg Val Ser Gln Ile Leu Gln Glu His Gly His Asn Val Thr 
            20                  25                  30          


Met Leu His Gln Ser Gly Lys Phe Leu Ile Pro Asp Ile Lys Glu Glu 
        35                  40                  45              


Glu Lys Ser Tyr Gln Val Ile Arg Trp Phe Ser Pro Glu Asp His Gln 
    50                  55                  60                  


Lys Arg Ile Lys Lys His Phe Asp Ser Tyr Ile Glu Thr Ala Leu Asp 
65                  70                  75                  80  


Gly Arg Lys Glu Ser Glu Ala Leu Val Lys Leu Met Glu Ile Phe Gly 
                85                  90                  95      


Thr Gln Cys Ser Tyr Leu Leu Ser Arg Lys Asp Ile Met Asp Ser Leu 
            100                 105                 110         


Lys Asn Glu Asn Tyr Asp Leu Val Phe Val Glu Ala Phe Asp Phe Cys 
        115                 120                 125             


Ser Phe Leu Ile Ala Glu Lys Leu Val Lys Pro Phe Val Ala Ile Leu 
    130                 135                 140                 


Pro Thr Thr Phe Gly Ser Leu Asp Phe Gly Leu Pro Ser Pro Leu Ser 
145                 150                 155                 160 


Tyr Val Pro Val Phe Pro Ser Leu Leu Thr Asp His Met Asp Phe Trp 
                165                 170                 175     


Gly Arg Val Lys Asn Phe Leu Met Phe Phe Ser Phe Ser Arg Ser Gln 
            180                 185                 190         


Trp Asp Met Gln Ser Thr Phe Asp Asn Thr Ile Lys Glu His Phe Pro 
        195                 200                 205             


Glu Gly Ser Arg Pro Val Leu Ser His Leu Leu Leu Lys Ala Glu Leu 
    210                 215                 220                 


Trp Phe Val Asn Ser Asp Phe Ala Phe Asp Phe Ala Arg Pro Leu Leu 
225                 230                 235                 240 


Pro Asn Thr Val Tyr Ile Gly Gly Leu Met Glu Lys Pro Ile Lys Pro 
                245                 250                 255     


Val Pro Gln Asp Leu Asp Asn Phe Ile Ala Asn Phe Gly Asp Ala Gly 
            260                 265                 270         


Phe Val Leu Val Ala Phe Gly Ser Met Leu Asn Thr His Gln Ser Gln 
        275                 280                 285             


Glu Val Leu Lys Lys Met His Asn Ala Phe Ala His Leu Pro Gln Gly 
    290                 295                 300                 


Val Ile Trp Thr Cys Gln Ser Ser His Trp Pro Arg Asp Val His Leu 
305                 310                 315                 320 


Ala Thr Asn Val Lys Ile Val Asp Trp Leu Pro Gln Ser Asp Leu Leu 
                325                 330                 335     


Ala His Pro Ser Ile Arg Leu Phe Val Thr His Gly Gly Gln Asn Ser 
            340                 345                 350         


Val Met Glu Ala Ile Arg His Gly Val Pro Met Val Gly Leu Pro Val 
        355                 360                 365             


Asn Gly Asp Gln His Gly Asn Met Val Arg Val Val Ala Lys Asn Tyr 
    370                 375                 380                 


Gly Val Ser Ile Arg Leu Asn Gln Val Thr Ala Asp Thr Leu Thr Leu 
385                 390                 395                 400 


Thr Met Lys Gln Val Ile Glu Asp Lys Arg Tyr Lys Ser Ala Val Val 
                405                 410                 415     


Ala Ala Ser Val Ile Leu His Ser Gln Pro Leu Ser Pro Ala Gln Arg 
            420                 425                 430         


Leu Val Gly Trp Ile Asp His Ile Leu Gln Thr Gly Gly Ala Thr His 
        435                 440                 445             


Leu Lys Pro Tyr Ala Phe Gln Gln Pro Trp His Glu Gln 
    450                 455                 460     


<210>  2523
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  2523

Met Gly Ala Gln Val Arg Leu Pro Pro Gly Glu Pro Cys Arg Glu Gly 
1               5                   10                  15      


Tyr Val Leu Ser Leu Val Cys Pro Asn Ser Ser Gln Ala Trp Cys Glu 
            20                  25                  30          


Ile Thr Asn Val Ser Gln Leu Leu Ala Ser Pro Val Leu Tyr Thr Asp 
        35                  40                  45              


Leu Asn Tyr Ser Ile Asn Asn Leu Ser Ile Ser Ala Asn Val Glu Asn 
    50                  55                  60                  


Lys Tyr Ser 
65          


<210>  2524
<211>  368
<212>  PRT
<213>  Homo Sapiens

<400>  2524

Gly Asp Cys Gln Gln Pro Ala Gln Cys Arg Ile Gln Lys Cys Thr Thr 
1               5                   10                  15      


Asp Phe Val Ser Leu Thr Ser His Leu Asn Ser Ala Val Asp Gly Phe 
            20                  25                  30          


Asp Ser Glu Phe Cys Lys Ala Leu Arg Ala Tyr Ala Gly Cys Thr Gln 
        35                  40                  45              


Arg Thr Ser Lys Ala Cys Arg Gly Asn Leu Val Tyr His Ser Ala Val 
    50                  55                  60                  


Leu Gly Ile Ser Asp Leu Met Ser Gln Arg Asn Cys Ser Lys Asp Gly 
65                  70                  75                  80  


Pro Thr Ser Ser Thr Asn Pro Glu Val Thr His Asp Pro Cys Asn Tyr 
                85                  90                  95      


His Ser His Ala Gly Ala Arg Glu His Arg Arg Gly Asp Gln Asn Pro 
            100                 105                 110         


Pro Ser Tyr Leu Phe Cys Gly Leu Phe Gly Asp Pro His Leu Arg Thr 
        115                 120                 125             


Phe Lys Asp Asn Phe Gln Thr Cys Lys Val Glu Gly Ala Trp Pro Leu 
    130                 135                 140                 


Ile Asp Asn Asn Tyr Leu Ser Val Gln Val Thr Asn Val Pro Val Val 
145                 150                 155                 160 


Pro Gly Ser Ser Ala Thr Ala Thr Asn Lys Ile Thr Ile Ile Phe Lys 
                165                 170                 175     


Ala His His Gly Cys Thr Asp Gln Lys Val Tyr Gln Ala Val Thr Asp 
            180                 185                 190         


Asp Leu Pro Ala Ala Phe Val Asp Gly Thr Thr Ser Gly Gly Asp Ser 
        195                 200                 205             


Asp Ala Lys Ser Leu Arg Ile Val Glu Arg Glu Ser Gly His Tyr Val 
    210                 215                 220                 


Glu Met His Ala Arg Tyr Ile Gly Thr Thr Val Phe Val Arg Gln Val 
225                 230                 235                 240 


Gly Arg Tyr Leu Thr Leu Ala Ile Arg Met Pro Glu Asp Leu Ala Met 
                245                 250                 255     


Ser Tyr Glu Glu Ser Gln Asp Leu Gln Leu Cys Val Asn Gly Cys Pro 
            260                 265                 270         


Leu Ser Glu Arg Ile Asp Asp Gly Gln Gly Gln Val Ser Ala Ile Leu 
        275                 280                 285             


Gly His Ser Leu Pro Arg Thr Ser Leu Val Gln Ala Trp Pro Gly Tyr 
    290                 295                 300                 


Thr Leu Glu Thr Ala Asn Thr Gln Cys His Glu Lys Met Pro Val Lys 
305                 310                 315                 320 


Asp Ile Tyr Phe Gln Ser Cys Val Phe Asp Leu Leu Thr Thr Gly Asp 
                325                 330                 335     


Ala Asn Phe Thr Ala Ala Ala His Ser Ala Leu Glu Asp Val Glu Ala 
            340                 345                 350         


Leu His Pro Arg Lys Glu Arg Trp His Ile Phe Pro Ser Ser Gly Asn 
        355                 360                 365             


<210>  2525
<211>  383
<212>  PRT
<213>  Homo Sapiens

<400>  2525

Phe Tyr Thr Pro Met Pro Asp Asn Ile Glu Glu Ser Trp Lys Ile Met 
1               5                   10                  15      


Ala Leu Asp Ala Ile Ala Lys Thr Cys Thr Phe Thr Ala Met Cys Phe 
            20                  25                  30          


Glu Asn Met Arg Ile Met Arg Tyr Glu Glu Phe Ile Ser Met Ile Phe 
        35                  40                  45              


Arg Leu Asp Tyr Thr Gln Pro Leu Ser Asp Glu Tyr Ile Thr Val Thr 
    50                  55                  60                  


Asp Thr Thr Phe Val Asp Ile Pro Val Arg Leu Tyr Leu Pro Lys Arg 
65                  70                  75                  80  


Lys Ser Glu Thr Arg Arg Arg Ala Val Ile Tyr Phe His Gly Gly Gly 
                85                  90                  95      


Phe Cys Phe Gly Ser Ser Lys Gln Arg Ala Phe Asp Phe Leu Asn Arg 
            100                 105                 110         


Trp Thr Ala Asn Thr Leu Asp Ala Val Val Val Gly Val Asp Tyr Arg 
        115                 120                 125             


Leu Ala Pro Gln His His Phe Pro Ala Gln Phe Glu Asp Gly Leu Ala 
    130                 135                 140                 


Ala Val Lys Phe Phe Leu Leu Glu Lys Ile Leu Thr Lys Tyr Gly Val 
145                 150                 155                 160 


Asp Pro Thr Arg Ile Cys Ile Ser Gly Asp Ser Ser Gly Gly Asn Leu 
                165                 170                 175     


Ala Thr Ala Val Thr Gln Gln Val Gln Asn Asp Ala Glu Ile Lys His 
            180                 185                 190         


Lys Ile Lys Met Gln Val Leu Leu Tyr Pro Gly Leu Gln Ile Thr Asp 
        195                 200                 205             


Ser Tyr Leu Pro Ser His Arg Glu Asn Glu His Gly Ile Val Leu Thr 
    210                 215                 220                 


Arg Asp Val Ala Ile Lys Leu Val Ser Leu Tyr Phe Thr Lys Asp Glu 
225                 230                 235                 240 


Ala Leu Pro Trp Ala Met Arg Arg Asn Gln His Met Pro Leu Glu Ser 
                245                 250                 255     


Arg His Leu Phe Lys Phe Val Asn Trp Ser Ile Leu Leu Pro Glu Lys 
            260                 265                 270         


Tyr Arg Lys Asp Tyr Val Tyr Thr Glu Pro Ile Leu Gly Gly Leu Ser 
        275                 280                 285             


Tyr Ser Leu Pro Gly Leu Thr Asp Ser Arg Ala Leu Pro Leu Leu Ala 
    290                 295                 300                 


Asn Asp Ser Gln Leu Gln Asn Leu Pro Leu Thr Tyr Ile Leu Thr Cys 
305                 310                 315                 320 


Gln His Asp Leu Leu Arg Asp Asp Gly Leu Met Tyr Val Thr Arg Leu 
                325                 330                 335     


Arg Asn Val Gly Val Gln Val Val His Glu His Ile Glu Asp Gly Ile 
            340                 345                 350         


His Gly Ala Leu Ser Phe Met Thr Ser Pro Phe Tyr Leu Arg Leu Gly 
        355                 360                 365             


Leu Arg Ile Arg Asp Met Tyr Val Ser Trp Leu Asp Lys Asn Leu 
    370                 375                 380             


<210>  2526
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  2526

Met Ala Pro Val Gly Gly Gly Gly Arg Pro Val Gly Gly Pro Ala Arg 
1               5                   10                  15      


Gly Arg Leu Leu Leu Ala Ala Pro Val Leu Leu Val Leu Leu Trp Ala 
            20                  25                  30          


Leu Gly Ala Arg Gly Gln Gly Ser Pro Gln Gln Gly Thr Ile Val Gly 
        35                  40                  45              


Met Arg Leu Ala Ser Cys Asn Lys Ser Cys Gly Thr Asn Pro Asp Gly 
    50                  55                  60                  


Ile Ile Phe Val Ser Glu Gly Ser Thr Val Asn Leu Arg Leu Tyr Gly 
65                  70                  75                  80  


Tyr Ser Leu Gly Asn Ile Ser Ser Asn Leu Ile Ser Phe Thr Glu Val 
                85                  90                  95      


Asp Asp Ala Glu Thr Leu His Lys Ser Thr Ser Cys Leu Glu Leu Thr 
            100                 105                 110         


Lys Asp Leu Val Val Gln Gln Leu Val Asn Val Ser Arg Arg Asn Thr 
        115                 120                 125             


Ser Gly Val Leu Val Val Leu Thr Lys Phe Leu Arg Arg Ser Glu Ser 
    130                 135                 140                 


Met Lys Leu Tyr Ala Leu Cys Thr Arg Ala Gln Pro Asp Gly Pro Trp 
145                 150                 155                 160 


Leu Lys Trp Thr Asp Lys Asp Ser Leu Leu Phe Met Val Glu Glu Pro 
                165                 170                 175     


Gly Arg 
        


<210>  2527
<211>  305
<212>  PRT
<213>  Homo Sapiens

<400>  2527

Ser Pro Pro Ala Gly Leu Leu Ser Leu Leu Thr Ser Gly Gln Gly Ala 
1               5                   10                  15      


Leu Asp Gln Glu Ala Leu Gly Gly Leu Leu Asn Thr Leu Ala Asp Arg 
            20                  25                  30          


Val His Cys Thr Asn Gly Pro Cys Gly Lys Cys Leu Ser Val Glu Asp 
        35                  40                  45              


Ala Leu Gly Leu Gly Glu Pro Glu Gly Ser Gly Leu Pro Pro Gly Pro 
    50                  55                  60                  


Val Leu Glu Ala Arg Tyr Val Ala Arg Leu Ser Ala Ala Ala Val Leu 
65                  70                  75                  80  


Tyr Leu Ser Asn Pro Glu Gly Thr Cys Glu Asp Thr Arg Ala Gly Leu 
                85                  90                  95      


Trp Ala Ser His Ala Asp His Leu Leu Ala Leu Leu Glu Ser Pro Lys 
            100                 105                 110         


Ala Leu Thr Pro Gly Leu Ser Trp Leu Leu Gln Arg Met Gln Ala Arg 
        115                 120                 125             


Ala Ala Gly Gln Thr Pro Lys Thr Ala Cys Val Asp Ile Pro Gln Leu 
    130                 135                 140                 


Leu Glu Glu Ala Val Gly Ala Gly Ala Pro Gly Ser Ala Gly Gly Val 
145                 150                 155                 160 


Leu Ala Ala Leu Leu Asp His Val Arg Ser Gly Ser Cys Phe His Ala 
                165                 170                 175     


Leu Pro Ser Pro Gln Tyr Phe Val Asp Phe Val Phe Gln Gln His Ser 
            180                 185                 190         


Ser Glu Val Pro Met Thr Leu Ala Glu Leu Ser Ala Leu Met Gln Arg 
        195                 200                 205             


Leu Gly Val Gly Arg Glu Ala His Ser Asp His Ser His Arg His Arg 
    210                 215                 220                 


Gly Ala Ser Ser Arg Asp Pro Val Pro Leu Ile Ser Ser Ser Asn Ser 
225                 230                 235                 240 


Ser Ser Val Trp Asp Thr Val Cys Leu Ser Ala Arg Asp Val Met Ala 
                245                 250                 255     


Ala Tyr Gly Leu Ser Glu Gln Ala Gly Val Thr Pro Glu Ala Trp Ala 
            260                 265                 270         


Gln Leu Ser Pro Ala Leu Leu Gln Gln Gln Leu Ser Gly Ala Cys Thr 
        275                 280                 285             


Ser Gln Ser Arg Pro Pro Val Gln Asp Gln Leu Ser Gln Ser Glu Arg 
    290                 295                 300                 


Tyr 
305 


<210>  2528
<211>  323
<212>  PRT
<213>  Homo Sapiens

<400>  2528

Glu Leu Ser Arg Ser Asp Leu Ser Leu Ile Gln Gln Gln Gln Gln Gln 
1               5                   10                  15      


Gln Gln Gln Gln Gln Gln Gln Gln Gln Gln Lys Gln Leu Glu Glu Ala 
            20                  25                  30          


Glu Glu Glu Arg Thr Glu Val Pro Gly Ala Thr Ser Thr Leu Thr Val 
        35                  40                  45              


Pro Val Ser Val Phe Met Leu Lys Val Gln Val Asn Asp Ile Ile Ser 
    50                  55                  60                  


Arg Gln Tyr Leu Ser Gln Ala Val Val Glu Val Phe Val Asn Tyr Thr 
65                  70                  75                  80  


Lys Thr Asn Ser Thr Val Thr Lys Ser Asn Gly Ala Val Leu Ile Lys 
                85                  90                  95      


Val Pro Tyr Lys Leu Gly Leu Ser Leu Thr Ile Ile Ala Tyr Lys Asp 
            100                 105                 110         


Gly Tyr Val Leu Thr Pro Leu Pro Trp Lys Thr Arg Arg Met Pro Ile 
        115                 120                 125             


Tyr Ser Ser Val Thr Leu Ser Leu Phe Pro Gln Ser Gln Ala Asn Ile 
    130                 135                 140                 


Trp Leu Phe Glu Asp Thr Val Leu Ile Thr Gly Lys Leu Ala Asp Ala 
145                 150                 155                 160 


Lys Ser Gln Pro Ser Val Gln Phe Ser Lys Ala Leu Ile Lys Leu Pro 
                165                 170                 175     


Asp Asn His His Ile Ser Asn Val Thr Gly Tyr Leu Thr Val Leu Gln 
            180                 185                 190         


Gln Phe Leu Lys Val Asp Asn Phe Leu His Thr Thr Gly Ile Thr Leu 
        195                 200                 205             


Asn Lys Pro Gly Phe Glu Asn Ile Glu Leu Thr Pro Leu Ala Ala Ile 
    210                 215                 220                 


Cys Val Lys Ile Tyr Ser Gly Gly Lys Glu Leu Lys Val Asn Gly Ser 
225                 230                 235                 240 


Ile Gln Val Ser Leu Pro Leu Leu Arg Leu Asn Asp Ile Ser Ala Gly 
                245                 250                 255     


Asp Arg Ile Pro Ala Trp Thr Phe Asp Met Asn Thr Gly Ala Trp Ile 
            260                 265                 270         


Asn His Gly Arg Gly Met Val Lys Glu His Asn Asn His Leu Ile Trp 
        275                 280                 285             


Thr Tyr Asp Ala Pro His Leu Gly Tyr Trp Ile Ala Ala Pro Leu Pro 
    290                 295                 300                 


Gly Thr Arg Gly Ser Gly Ile Asn Glu Asp Ser Lys Asp Ile Thr Ala 
305                 310                 315                 320 


Tyr His Thr 
            


<210>  2529
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2529

Asn Tyr Glu Glu Leu Glu Asn Ser Gly Asp Thr Thr Val Glu Ser Glu 
1               5                   10                  15      


Arg Pro Asn Lys Val Thr Ile Pro Ser Thr Phe Ala Ala Val Thr Ile 
            20                  25                  30          


Lys Glu Thr Leu Asn Ala Asn Ile Asn Ser Thr Asn Phe Ala Pro Asp 
        35                  40                  45              


Glu Asn Gln Leu Glu 
    50              


<210>  2530
<211>  59
<212>  PRT
<213>  Homo Sapiens

<400>  2530

Asp Gln Val Asp Trp Ser Arg Leu Tyr Arg Asp Thr Gly Leu Val Lys 
1               5                   10                  15      


Met Ser Arg Lys Pro Arg Ala Ser Ser Pro Phe Ser Asn Asn His Pro 
            20                  25                  30          


Ser Thr Pro Lys Arg Phe Pro Arg Gln Pro Arg Arg Glu Lys Gly Pro 
        35                  40                  45              


Val Lys Glu Val Pro Gly Thr Lys Gly Ser Pro 
    50                  55                  


<210>  2531
<211>  151
<212>  PRT
<213>  Homo Sapiens

<400>  2531

Gly Ser Ala Gln Gly Pro Pro Lys Pro Arg Leu Gln Thr Leu Arg Met 
1               5                   10                  15      


Thr Leu Pro Ser Pro His Met Pro Arg Pro Asn Gln Thr Ile Leu Val 
            20                  25                  30          


Asp Val Ala Arg Asn Ala Ala Thr Ile Thr Val Thr Pro Pro Gln Ser 
        35                  40                  45              


Asn His Ser Trp Ala Val Leu Phe Asp Gly Gln Ser Gly Cys Ile Cys 
    50                  55                  60                  


Tyr Arg Pro Glu Glu His Gln Val Cys Phe Leu Arg Leu Met Glu Asp 
65                  70                  75                  80  


Ser Asp Arg Glu Thr Leu Arg Leu Leu Val Asp Thr Ser Lys Val Gln 
                85                  90                  95      


Glu Ala Trp Val Pro Ser Gln Asp Thr His His Thr Gln Glu Leu Leu 
            100                 105                 110         


Ala Val Gln Gly Ser Leu Glu Val Asp Pro Ala Gln Ala Gly Ala Leu 
        115                 120                 125             


Val Gln Arg Leu Cys Met Arg Thr Pro Ile Tyr Trp Ala Arg Arg Ala 
    130                 135                 140                 


Glu Gly Pro Arg Arg Gln Arg 
145                 150     


<210>  2532
<211>  343
<212>  PRT
<213>  Homo Sapiens

<400>  2532

Arg Lys Gly Phe Trp Asp Tyr Phe Ser Gln Thr Ser Gly Asp Lys Gly 
1               5                   10                  15      


Arg Val Glu Gln Ile His Gln Gln Lys Met Ala Arg Glu Pro Ala Thr 
            20                  25                  30          


Leu Lys Asp Ser Leu Glu Gln Asp Leu Asn Asn Met Asn Lys Phe Leu 
        35                  40                  45              


Glu Lys Leu Arg Pro Leu Ser Gly Ser Glu Ala Pro Arg Leu Pro Gln 
    50                  55                  60                  


Asp Pro Val Gly Met Arg Arg Gln Leu Gln Glu Glu Leu Glu Glu Val 
65                  70                  75                  80  


Lys Ala Arg Leu Gln Pro Tyr Met Ala Glu Ala His Glu Leu Val Gly 
                85                  90                  95      


Trp Asn Leu Glu Gly Leu Arg Gln Gln Leu Lys Pro Tyr Thr Met Asp 
            100                 105                 110         


Leu Met Glu Gln Val Ala Leu Arg Val Gln Glu Leu Gln Glu Gln Leu 
        115                 120                 125             


Arg Val Val Gly Glu Asp Thr Lys Ala Gln Leu Leu Gly Gly Val Asp 
    130                 135                 140                 


Glu Ala Trp Ala Leu Leu Gln Gly Leu Gln Ser Arg Val Val His His 
145                 150                 155                 160 


Thr Gly Arg Phe Lys Glu Leu Phe His Pro Tyr Ala Glu Ser Leu Val 
                165                 170                 175     


Ser Gly Ile Gly Arg His Val Gln Glu Leu His Arg Ser Val Ala Pro 
            180                 185                 190         


His Ala Pro Ala Ser Pro Ala Arg Leu Ser Arg Cys Val Gln Val Leu 
        195                 200                 205             


Ser Arg Lys Leu Thr Leu Lys Ala Lys Ala Leu His Ala Arg Ile Gln 
    210                 215                 220                 


Gln Asn Leu Asp Gln Leu Arg Glu Glu Leu Ser Arg Ala Phe Ala Gly 
225                 230                 235                 240 


Thr Gly Thr Glu Glu Gly Ala Gly Pro Asp Pro Gln Met Leu Ser Glu 
                245                 250                 255     


Glu Val Arg Gln Arg Leu Gln Ala Phe Arg Gln Asp Thr Tyr Leu Gln 
            260                 265                 270         


Ile Ala Ala Phe Thr Arg Ala Ile Asp Gln Glu Thr Glu Glu Val Gln 
        275                 280                 285             


Gln Gln Leu Ala Pro Pro Pro Pro Gly His Ser Ala Phe Ala Pro Glu 
    290                 295                 300                 


Phe Gln Gln Thr Asp Ser Gly Lys Val Leu Ser Lys Leu Gln Ala Arg 
305                 310                 315                 320 


Leu Asp Asp Leu Trp Glu Asp Ile Thr His Ser Leu His Asp Gln Gly 
                325                 330                 335     


His Ser His Leu Gly Asp Pro 
            340             


<210>  2533
<211>  538
<212>  PRT
<213>  Homo Sapiens

<400>  2533

Met Ala Gly Pro Pro Ala Leu Pro Pro Pro Glu Thr Ala Ala Ala Ala 
1               5                   10                  15      


Thr Thr Ala Ala Ala Ala Ser Ser Ser Ala Ala Ser Pro His Tyr Gln 
            20                  25                  30          


Glu Trp Ile Leu Asp Thr Ile Asp Ser Leu Arg Ser Arg Lys Ala Arg 
        35                  40                  45              


Pro Asp Leu Glu Arg Ile Cys Arg Met Val Arg Arg Arg His Gly Pro 
    50                  55                  60                  


Glu Pro Glu Arg Thr Arg Ala Glu Leu Glu Lys Leu Ile Gln Gln Arg 
65                  70                  75                  80  


Ala Val Leu Arg Val Ser Tyr Lys Gly Ser Ile Ser Tyr Arg Asn Ala 
                85                  90                  95      


Ala Arg Val Gln Pro Pro Arg Arg Gly Ala Thr Pro Pro Ala Pro Pro 
            100                 105                 110         


Arg Ala Pro Arg Gly Ala Pro Ala Ala Ala Ala Ala Ala Ala Pro Pro 
        115                 120                 125             


Pro Thr Pro Ala Pro Pro Pro Pro Pro Ala Pro Val Ala Ala Ala Ala 
    130                 135                 140                 


Pro Ala Arg Ala Pro Arg Ala Ala Ala Ala Ala Ala Thr Ala Pro Pro 
145                 150                 155                 160 


Ser Pro Gly Pro Ala Gln Pro Gly Pro Arg Ala Gln Arg Ala Ala Pro 
                165                 170                 175     


Leu Ala Ala Pro Pro Pro Ala Pro Ala Ala Pro Pro Ala Val Ala Pro 
            180                 185                 190         


Pro Ala Gly Pro Arg Arg Ala Pro Pro Pro Ala Val Ala Ala Arg Glu 
        195                 200                 205             


Pro Pro Leu Pro Pro Pro Pro Gln Pro Pro Ala Pro Pro Gln Gln Gln 
    210                 215                 220                 


Gln Pro Pro Pro Pro Gln Pro Gln Pro Pro Pro Glu Gly Gly Ala Val 
225                 230                 235                 240 


Arg Ala Gly Gly Ala Ala Arg Pro Val Ser Leu Arg Glu Val Val Arg 
                245                 250                 255     


Tyr Leu Gly Gly Ser Gly Gly Ala Gly Gly Arg Leu Thr Arg Gly Arg 
            260                 265                 270         


Val Gln Gly Leu Leu Glu Glu Glu Ala Ala Ala Arg Gly Arg Leu Glu 
        275                 280                 285             


Arg Thr Arg Leu Gly Ala Leu Ala Leu Pro Arg Gly Asp Arg Pro Gly 
    290                 295                 300                 


Arg Ala Pro Pro Ala Ala Ser Ala Arg Pro Ser Arg Ser Lys Arg Gly 
305                 310                 315                 320 


Gly Glu Glu Arg Val Leu Glu Lys Glu Glu Glu Glu Asp Asp Asp Glu 
                325                 330                 335     


Asp Glu Asp Glu Glu Asp Asp Val Ser Glu Gly Ser Glu Val Pro Glu 
            340                 345                 350         


Ser Asp Arg Pro Ala Gly Ala Gln His His Gln Leu Asn Gly Glu Arg 
        355                 360                 365             


Gly Pro Gln Ser Ala Lys Glu Arg Val Lys Glu Trp Thr Pro Cys Gly 
    370                 375                 380                 


Pro His Gln Gly Gln Asp Glu Gly Arg Gly Pro Ala Pro Gly Ser Gly 
385                 390                 395                 400 


Thr Arg Gln Val Phe Ser Met Ala Ala Met Asn Lys Glu Gly Gly Thr 
                405                 410                 415     


Ala Ser Val Ala Thr Gly Pro Asp Ser Pro Ser Pro Val Pro Leu Pro 
            420                 425                 430         


Pro Gly Lys Pro Ala Leu Pro Gly Ala Asp Gly Thr Pro Phe Gly Cys 
        435                 440                 445             


Pro Pro Gly Arg Lys Glu Lys Pro Ser Asp Pro Val Glu Trp Thr Val 
    450                 455                 460                 


Met Asp Val Val Glu Tyr Phe Thr Glu Ala Gly Phe Pro Glu Gln Ala 
465                 470                 475                 480 


Thr Ala Phe Gln Glu Gln Glu Ile Asp Gly Lys Ser Leu Leu Leu Met 
                485                 490                 495     


Gln Arg Thr Asp Val Leu Thr Gly Leu Ser Ile Arg Leu Gly Pro Ala 
            500                 505                 510         


Leu Lys Ile Tyr Glu His His Ile Lys Val Leu Gln Gln Gly His Phe 
        515                 520                 525             


Glu Asp Asp Asp Pro Asp Gly Phe Leu Gly 
    530                 535             


<210>  2534
<211>  252
<212>  PRT
<213>  Homo Sapiens

<400>  2534

Arg Pro Pro Pro Phe Leu Phe Cys Pro Leu Ser Ser Gln Arg Thr Glu 
1               5                   10                  15      


Ser Pro Tyr Lys Pro Val His Leu Gly Leu Gly Pro Thr Asp Lys Val 
            20                  25                  30          


Ala Ala Ile Ala Met Ala Arg Ile Ile Asp Leu Val Pro Trp Asp Asp 
        35                  40                  45              


Gly Ser Thr His Val Tyr Ala Ser Pro Ala Ile Leu Leu Pro Met Glu 
    50                  55                  60                  


Arg Gln Arg Asn Gln Leu Ala Gly Val Lys Gln Gln Leu Tyr His Pro 
65                  70                  75                  80  


Ala Leu Pro Thr Leu Arg His Met Asp Arg Asp Thr Val Lys Ala Cys 
                85                  90                  95      


Leu Pro Asp Glu His Cys Gln Ser Thr Thr Tyr Cys Arg Lys Asp Glu 
            100                 105                 110         


Phe Asp Asn Ala His Phe Thr Leu Leu Gly Val Pro Asn Lys Pro Leu 
        115                 120                 125             


Gln Cys Leu Asp Ile Thr Ala Thr Gly Gln Lys Leu Arg Asn Arg Tyr 
    130                 135                 140                 


His Glu Gly Lys Leu Ala Pro Ile Ala Pro Gly Ile Asn Arg Val Asp 
145                 150                 155                 160 


Trp Pro Cys Phe Thr Arg Ala Ile Glu Asp Trp Ser His Phe Val Ser 
                165                 170                 175     


Ser Ala Gly Glu Phe Lys Leu Pro Cys Leu Arg Lys Arg Ala Glu Gly 
            180                 185                 190         


Leu Ser Gly Tyr Ala Val Arg Tyr Leu Lys Pro Asp Val Thr Gln Thr 
        195                 200                 205             


Trp Arg Tyr Cys Leu Asn Gln Asn Pro Ser Leu Asp Arg Tyr Gly Gln 
    210                 215                 220                 


Lys Pro Leu Pro Phe Asp Ser Leu Asn Thr Phe Arg Ser Phe Gly Ser 
225                 230                 235                 240 


Ser Tyr Ser Arg Val Asn Tyr Leu Thr Pro Trp His 
                245                 250         


<210>  2535
<211>  59
<212>  PRT
<213>  Homo Sapiens

<400>  2535

Thr Gly Pro Gly Met Thr Leu Gln Leu Lys Leu Lys Glu Ser Phe Leu 
1               5                   10                  15      


Thr Asn Ser Ser Tyr Glu Ser Ser Phe Leu Glu Leu Leu Glu Lys Leu 
            20                  25                  30          


Cys Leu Leu Leu His Leu Pro Ser Gly Thr Ser Val Thr Leu His His 
        35                  40                  45              


Ala Arg Ser Gln His His Val Val Cys Asn Thr 
    50                  55                  


<210>  2536
<211>  331
<212>  PRT
<213>  Homo Sapiens

<400>  2536

Tyr Pro Ser Ile Thr Val Thr Pro Asp Glu Glu Gln Asn Leu Asn His 
1               5                   10                  15      


Tyr Ile Gln Val Leu Glu Asn Leu Val Arg Ser Val Pro Ser Gly Glu 
            20                  25                  30          


Pro Gly Arg Glu Lys Lys Ser Asn Ser Pro Lys His Val Tyr Ser Ile 
        35                  40                  45              


Ala Ser Lys Gly Ser Lys Phe Lys Glu Leu Val Thr His Gly Asp Ala 
    50                  55                  60                  


Ser Thr Glu Asn Asp Val Leu Thr Asn Pro Ile Ser Glu Glu Thr Thr 
65                  70                  75                  80  


Thr Phe Pro Thr Gly Gly Phe Thr Pro Glu Ile Gly Lys Lys Lys His 
                85                  90                  95      


Thr Glu Ser Thr Pro Phe Trp Ser Ile Lys Pro Asn Asn Val Ser Ile 
            100                 105                 110         


Val Leu His Ala Glu Glu Pro Tyr Ile Glu Asn Glu Glu Pro Glu Pro 
        115                 120                 125             


Glu Pro Glu Pro Ala Ala Lys Gln Thr Glu Ala Pro Arg Met Leu Pro 
    130                 135                 140                 


Val Val Thr Glu Ser Ser Thr Ser Pro Tyr Val Thr Ser Tyr Lys Ser 
145                 150                 155                 160 


Pro Val Thr Thr Leu Asp Lys Ser Thr Gly Ile Gly Ile Ser Thr Glu 
                165                 170                 175     


Ser Glu Asp Val Pro Gln Leu Ser Gly Glu Thr Ala Ile Glu Lys Pro 
            180                 185                 190         


Glu Glu Phe Gly Lys His Pro Glu Ser Trp Asn Asn Asp Asp Ile Leu 
        195                 200                 205             


Lys Lys Ile Leu Asp Ile Asn Ser Gln Val Gln Gln Ala Leu Leu Ser 
    210                 215                 220                 


Asp Thr Ser Asn Pro Ala Tyr Arg Glu Asp Ile Glu Ala Ser Lys Asp 
225                 230                 235                 240 


His Leu Lys Arg Ser Leu Ala Leu Ala Ala Ala Ala Glu His Lys Leu 
                245                 250                 255     


Lys Thr Met Tyr Lys Ser Gln Leu Leu Pro Val Gly Arg Thr Ser Asn 
            260                 265                 270         


Lys Ile Asp Asp Ile Glu Thr Val Ile Asn Met Leu Cys Asn Ser Arg 
        275                 280                 285             


Ser Lys Leu Tyr Glu Tyr Leu Asp Ile Lys Cys Val Pro Pro Glu Met 
    290                 295                 300                 


Arg Glu Lys Ala Ala Thr Val Phe Asn Thr Leu Lys Asn Met Cys Arg 
305                 310                 315                 320 


Ser Arg Arg Val Thr Ala Leu Leu Lys Val Tyr 
                325                 330     


<210>  2537
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  2537

Ser Met Cys His Arg Trp Ser Arg Ala Val Leu Phe Pro Ala Ala His 
1               5                   10                  15      


Arg Pro Lys Arg Ser Ser Ser Leu Pro Leu Asn Pro Val Leu Gln Thr 
            20                  25                  30          


Ser Leu Glu Glu Val Glu Leu Leu Tyr Glu Phe Leu Leu Ala Glu Leu 
        35                  40                  45              


Glu Ile Ser Pro Asp Leu Gln Ile Ser Ile Lys Asp Glu Glu Leu Ala 
    50                  55                  60                  


Ser Leu Arg Lys Ala Ser Asp Phe Arg Thr Val Cys Asn Asn Val Ile 
65                  70                  75                  80  


Pro Lys Ser Ile Pro Asp Ile Arg Arg Leu Ser Ala Ser Leu Ser Ser 
                85                  90                  95      


His Pro Gly Ile Leu Lys Lys Glu Asp Phe Glu Arg Thr Val Leu Thr 
            100                 105                 110         


Leu Ala Tyr Thr Ala Tyr Arg Thr Ala Leu Ser His Gly His Gln Lys 
        115                 120                 125             


Asp Ile Trp Ala Gln Ser Leu Val Ser Leu Phe Gln Ala Leu Arg His 
    130                 135                 140                 


Asp Leu Met Arg Ser Ser Gln Pro Gly Val Pro Pro 
145                 150                 155     


<210>  2538
<211>  464
<212>  PRT
<213>  Homo Sapiens

<400>  2538

Gly Arg Ala Ser Leu Gln His Gly Gln Ala Ala Glu Lys Gly Pro His 
1               5                   10                  15      


Arg Ser Arg Asp Thr Ala Glu Pro Ser Phe Pro Glu Ile Pro Leu Asp 
            20                  25                  30          


Gly Thr Leu Ala Pro Pro Glu Ser Gln Gly Asn Gly Ser Thr Leu Gln 
        35                  40                  45              


Pro Asn Val Val Tyr Ile Thr Leu Arg Ser Lys Arg Ser Lys Pro Ala 
    50                  55                  60                  


Asn Ile Arg Gly Thr Val Lys Pro Lys Arg Arg Lys Lys His Ala Val 
65                  70                  75                  80  


Ala Ser Ala Ala Pro Gly Gln Glu Ala Leu Val Gly Pro Ser Leu Gln 
                85                  90                  95      


Pro Gln Glu Ala Ala Arg Glu Ala Asp Ala Val Ala Pro Gly Tyr Ala 
            100                 105                 110         


Gln Gly Ala Asn Leu Val Lys Ile Gly Glu Arg Pro Trp Arg Leu Val 
        115                 120                 125             


Arg Gly Pro Gly Val Arg Ala Gly Gly Pro Asp Phe Leu Gln Pro Ser 
    130                 135                 140                 


Ser Arg Glu Ser Asn Ile Arg Ile Tyr Ser Glu Ser Ala Pro Ser Trp 
145                 150                 155                 160 


Leu Ser Lys Asp Asp Ile Arg Arg Met Arg Leu Leu Ala Asp Ser Ala 
                165                 170                 175     


Val Ala Gly Leu Arg Pro Val Ser Ser Arg Ser Gly Ala Arg Leu Leu 
            180                 185                 190         


Val Leu Glu Gly Gly Ala Pro Gly Ala Val Leu Arg Cys Gly Pro Ser 
        195                 200                 205             


Pro Cys Gly Leu Leu Lys Gln Pro Leu Asp Met Ser Glu Val Phe Ala 
    210                 215                 220                 


Phe His Leu Asp Arg Ile Leu Gly Leu Asn Arg Thr Leu Pro Ser Val 
225                 230                 235                 240 


Ser Arg Lys Ala Glu Phe Ile Gln Asp Gly Arg Pro Cys Pro Ile Ile 
                245                 250                 255     


Leu Trp Asp Ala Ser Leu Ser Ser Ala Ser Asn Asp Thr His Ser Ser 
            260                 265                 270         


Val Lys Leu Thr Trp Gly Thr Tyr Gln Gln Leu Leu Lys Gln Lys Cys 
        275                 280                 285             


Trp Gln Asn Gly Arg Val Pro Lys Pro Glu Ser Gly Cys Thr Glu Ile 
    290                 295                 300                 


His His His Glu Trp Ser Lys Met Ala Leu Phe Asp Phe Leu Leu Gln 
305                 310                 315                 320 


Ile Tyr Asn Arg Leu Asp Thr Asn Cys Cys Gly Phe Arg Pro Arg Lys 
                325                 330                 335     


Glu Asp Ala Cys Val Gln Asn Gly Leu Arg Pro Lys Cys Asp Asp Gln 
            340                 345                 350         


Gly Ser Ala Ala Leu Ala His Ile Ile Gln Arg Lys His Asp Pro Arg 
        355                 360                 365             


His Leu Val Phe Ile Asp Asn Lys Gly Phe Phe Asp Arg Ser Glu Asp 
    370                 375                 380                 


Asn Leu Asn Phe Lys Leu Leu Glu Gly Ile Lys Glu Phe Pro Ala Ser 
385                 390                 395                 400 


Ala Val Ser Val Leu Lys Ser Gln His Leu Arg Gln Lys Leu Leu Gln 
                405                 410                 415     


Ser Leu Phe Leu Asp Lys Val Tyr Trp Glu Ser Gln Gly Gly Arg Gln 
            420                 425                 430         


Gly Ile Glu Lys Leu Ile Asp Val Ile Glu His Arg Ala Lys Ile Leu 
        435                 440                 445             


Ile Thr Tyr Ile Asn Ala His Gly Val Lys Val Leu Pro Met Asn Glu 
    450                 455                 460                 


<210>  2539
<211>  238
<212>  PRT
<213>  Homo Sapiens

<400>  2539

Leu Pro Thr Ser Ala Pro Leu Ser Val Ser Leu Pro Thr Asn Ile Val 
1               5                   10                  15      


Pro Pro Thr Thr Ile Trp Thr Ser Ser Pro Gln Asn Thr Asp Ala Asp 
            20                  25                  30          


Thr Ala Ser Pro Ser Asn Gly Thr His Asn Asn Ser Val Leu Pro Val 
        35                  40                  45              


Thr Ala Ser Ala Pro Thr Ser Leu Leu Pro Lys Asn Ile Ser Ile Glu 
    50                  55                  60                  


Ser Arg Glu Glu Glu Ile Thr Ser Pro Gly Ser Asn Trp Glu Gly Thr 
65                  70                  75                  80  


Asn Thr Asp Pro Ser Pro Ser Gly Phe Ser Ser Thr Ser Gly Gly Val 
                85                  90                  95      


His Leu Thr Thr Thr Leu Lys Glu His Ser Ser Gly Thr Pro Glu Ala 
            100                 105                 110         


Gly Val Ala Ala Thr Leu Ser Gln Ser Ala Ala Glu Pro Pro Thr Leu 
        115                 120                 125             


Ile Ser Pro Gln Ala Pro Ala Ser Ser Pro Ser Ser Leu Ser Thr Ser 
    130                 135                 140                 


Pro Pro Glu Val Phe Ser Ala Ser Val Thr Thr Asn His Ser Ser Thr 
145                 150                 155                 160 


Val Thr Ser Thr Gln Pro Thr Gly Ala Pro Thr Ala Pro Glu Ser Pro 
                165                 170                 175     


Thr Glu Glu Ser Ser Ser Asp His Thr Pro Thr Ser His Ala Thr Ala 
            180                 185                 190         


Glu Pro Val Pro Gln Glu Lys Thr Pro Pro Thr Thr Val Ser Gly Lys 
        195                 200                 205             


Val Met Cys Glu Leu Ile Asp Met Glu Thr Thr Thr Thr Phe Pro Arg 
    210                 215                 220                 


Val Ile Met Gln Glu Val Glu His Ala Leu Ser Ser Gly Ser 
225                 230                 235             


<210>  2540
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2540

Ser Gly Glu Tyr Cys His Gly Trp Leu Asp Ala Gln Gly Val Trp Arg 
1               5                   10                  15      


Ile Gly Phe Gln Cys Pro Glu Arg Phe Asp Gly Gly Asp Ala Thr Ile 
            20                  25                  30          


Cys Cys Gly Ser Cys Ala Leu Arg Tyr Cys Cys Ser Ser Ala Glu Ala 
        35                  40                  45              


Arg Leu Asp Gln Gly Gly Cys Asp Asn Asp Arg Gln Gln Gly Ala Gly 
    50                  55                  60                  


Glu Pro Gly Arg Ala Asp Lys Asp Gly Pro Asp Gly Ser 
65                  70                  75          


<210>  2541
<211>  263
<212>  PRT
<213>  Homo Sapiens

<400>  2541

Val Glu His Glu Glu Val Ala Gln Arg Val Ile Lys Leu His Arg Gly 
1               5                   10                  15      


Arg Gly Val Ala Ala Met Gln Ser Arg Gln Trp Val Arg Asp Ser Cys 
            20                  25                  30          


Arg Lys Leu Ser Gly Leu Leu Arg Gln Lys Asn Ala Val Leu Asn Lys 
        35                  40                  45              


Leu Lys Thr Ala Ile Gly Ala Val Glu Lys Asp Val Gly Leu Ser Asp 
    50                  55                  60                  


Glu Glu Lys Leu Phe Gln Val His Thr Phe Glu Ile Phe Gln Lys Glu 
65                  70                  75                  80  


Leu Asn Glu Ser Glu Asn Ser Val Phe Gln Ala Val Tyr Gly Leu Gln 
                85                  90                  95      


Arg Ala Leu Gln Gly Asp Tyr Lys Asp Val Val Asn Met Lys Glu Ser 
            100                 105                 110         


Ser Arg Gln Arg Leu Glu Ala Leu Arg Glu Ala Ala Ile Lys Glu Glu 
        115                 120                 125             


Thr Glu Tyr Met Glu Leu Leu Ala Ala Glu Lys His Gln Val Glu Ala 
    130                 135                 140                 


Leu Lys Asn Met Gln His Gln Asn Gln Ser Leu Ser Met Leu Asp Glu 
145                 150                 155                 160 


Ile Leu Glu Asp Val Arg Lys Ala Ala Asp Arg Leu Glu Glu Glu Ile 
                165                 170                 175     


Glu Glu His Ala Phe Asp Asp Asn Lys Ser Val Lys Gly Val Asn Phe 
            180                 185                 190         


Glu Ala Val Leu Arg Val Glu Glu Glu Glu Ala Asn Ser Lys Gln Asn 
        195                 200                 205             


Ile Thr Lys Arg Glu Val Glu Asp Asp Leu Gly Leu Ser Met Leu Ile 
    210                 215                 220                 


Asp Ser Gln Asn Asn Gln Tyr Ile Leu Thr Lys Pro Arg Asp Ser Thr 
225                 230                 235                 240 


Ile Pro Arg Ala Asp His His Phe Ile Lys Asp Ile Val Thr Ile Gly 
                245                 250                 255     


Met Leu Ser Leu Pro Cys Gly 
            260             


<210>  2542
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  2542

Gly Lys Gly Ala Arg Gly Phe Gly Arg Gly Ala Leu Ile Arg Leu Asn 
1               5                   10                  15      


Ile Trp Pro Ala Val Gln Gly Ala Cys Lys Gln Leu Glu Val Cys Glu 
            20                  25                  30          


His Cys Val Glu Gly Asp Arg Ala Arg Asn Leu Ser Ser Cys Met Trp 
        35                  40                  45              


Glu Gln Cys Arg Pro Glu Glu Pro Gly His Cys Val Ala Gln Ser Glu 
    50                  55                  60                  


Val Val Lys Glu Gly Cys Ser Ile Tyr Asn Arg Ser Glu Ala Cys Pro 
65                  70                  75                  80  


Ala Ala His His His Pro Thr Tyr Glu Pro Lys Thr Val Thr Thr Gly 
                85                  90                  95      


Ser Pro Pro Val Pro Glu Ala His Ser Pro Gly Phe Asp Gly Ala Ser 
            100                 105                 110         


<210>  2543
<211>  190
<212>  PRT
<213>  Homo Sapiens

<400>  2543

Ser Lys Ile Pro Ser Ile Thr Asp Pro His Phe Ile Asp Asn Cys Ile 
1               5                   10                  15      


Glu Ala His Asn Glu Trp Arg Gly Lys Val Asn Pro Pro Ala Ala Asp 
            20                  25                  30          


Met Lys Tyr Met Ile Trp Asp Lys Gly Leu Ala Lys Met Ala Lys Ala 
        35                  40                  45              


Trp Ala Asn Gln Cys Lys Phe Glu His Asn Asp Cys Leu Asp Lys Ser 
    50                  55                  60                  


Tyr Lys Cys Tyr Ala Ala Phe Glu Tyr Val Gly Glu Asn Ile Trp Leu 
65                  70                  75                  80  


Gly Gly Ile Lys Ser Phe Thr Pro Arg His Ala Ile Thr Ala Trp Tyr 
                85                  90                  95      


Asn Glu Thr Gln Phe Tyr Asp Phe Asp Ser Leu Ser Cys Ser Arg Val 
            100                 105                 110         


Cys Gly His Tyr Thr Gln Leu Val Trp Ala Asn Ser Phe Tyr Val Gly 
        115                 120                 125             


Cys Ala Val Ala Met Cys Pro Asn Leu Gly Gly Ala Ser Thr Ala Ile 
    130                 135                 140                 


Phe Val Cys Asn Tyr Gly Pro Ala Gly Asn Phe Ala Asn Met Pro Pro 
145                 150                 155                 160 


Tyr Val Arg Gly Glu Ser Cys Ser Leu Cys Ser Lys Glu Glu Lys Cys 
                165                 170                 175     


Val Lys Asn Leu Cys Lys Asn Pro Phe Leu Lys Pro Thr Gly 
            180                 185                 190 


<210>  2544
<211>  519
<212>  PRT
<213>  Homo Sapiens

<400>  2544

Arg Lys Gly Ser Pro Glu Glu Ala Ser Phe Tyr Tyr Gly Thr Phe Pro 
1               5                   10                  15      


Leu Gly Phe Ser Trp Gly Val Gly Ser Ser Ala Tyr Gln Thr Glu Gly 
            20                  25                  30          


Ala Trp Asp Gln Asp Gly Lys Gly Pro Ser Ile Trp Asp Val Phe Thr 
        35                  40                  45              


His Ser Gly Lys Gly Lys Val Leu Gly Asn Glu Thr Ala Asp Val Ala 
    50                  55                  60                  


Cys Asp Gly Tyr Tyr Lys Val Gln Glu Asp Ile Ile Leu Leu Arg Glu 
65                  70                  75                  80  


Leu His Val Asn His Tyr Arg Phe Ser Leu Ser Trp Pro Arg Leu Leu 
                85                  90                  95      


Pro Thr Gly Ile Arg Ala Glu Gln Val Asn Lys Lys Gly Ile Glu Phe 
            100                 105                 110         


Tyr Ser Asp Leu Ile Asp Ala Leu Leu Ser Ser Asn Ile Thr Pro Ile 
        115                 120                 125             


Val Thr Leu His His Trp Asp Leu Pro Gln Leu Leu Gln Val Lys Tyr 
    130                 135                 140                 


Gly Gly Trp Gln Asn Val Ser Met Ala Asn Tyr Phe Arg Asp Tyr Ala 
145                 150                 155                 160 


Asn Leu Cys Phe Glu Ala Phe Gly Asp Arg Val Lys His Trp Ile Thr 
                165                 170                 175     


Phe Ser Asp Pro Arg Ala Met Ala Glu Lys Gly Tyr Glu Thr Gly His 
            180                 185                 190         


His Ala Pro Gly Leu Lys Leu Arg Gly Thr Gly Leu Tyr Lys Ala Ala 
        195                 200                 205             


His His Ile Ile Lys Ala His Ala Lys Ala Trp His Ser Tyr Asn Thr 
    210                 215                 220                 


Thr Trp Arg Ser Lys Gln Gln Gly Leu Val Gly Ile Ser Leu Asn Cys 
225                 230                 235                 240 


Asp Trp Gly Glu Pro Val Asp Ile Ser Asn Pro Lys Asp Leu Glu Ala 
                245                 250                 255     


Ala Glu Arg Tyr Leu Gln Phe Cys Leu Gly Trp Phe Ala Asn Pro Ile 
            260                 265                 270         


Tyr Ala Gly Asp Tyr Pro Gln Val Met Lys Asp Tyr Ile Gly Arg Lys 
        275                 280                 285             


Ser Ala Glu Gln Gly Leu Glu Met Ser Arg Leu Pro Val Phe Ser Leu 
    290                 295                 300                 


Gln Glu Lys Ser Tyr Ile Lys Gly Thr Ser Asp Phe Leu Gly Leu Gly 
305                 310                 315                 320 


His Phe Thr Thr Arg Tyr Ile Thr Glu Arg Asn Tyr Pro Ser Arg Gln 
                325                 330                 335     


Gly Pro Ser Tyr Gln Asn Asp Arg Asp Leu Ile Glu Leu Val Asp Pro 
            340                 345                 350         


Asn Trp Pro Asp Leu Gly Ser Lys Trp Leu Tyr Ser Val Pro Trp Gly 
        355                 360                 365             


Phe Arg Arg Leu Leu Asn Phe Ala Gln Thr Gln Tyr Gly Asp Pro Pro 
    370                 375                 380                 


Ile Tyr Val Met Glu Asn Gly Ala Ser Gln Lys Phe His Cys Thr Gln 
385                 390                 395                 400 


Leu Cys Asp Glu Trp Arg Ile Gln Tyr Leu Lys Gly Tyr Ile Asn Glu 
                405                 410                 415     


Met Leu Lys Ala Ile Lys Asp Gly Ala Asn Ile Lys Gly Tyr Thr Ser 
            420                 425                 430         


Trp Ser Leu Leu Asp Lys Phe Glu Trp Glu Lys Gly Tyr Ser Asp Arg 
        435                 440                 445             


Tyr Gly Phe Tyr Tyr Val Glu Phe Asn Asp Arg Asn Lys Pro Arg Tyr 
    450                 455                 460                 


Pro Lys Ala Ser Val Gln Tyr Tyr Lys Lys Ile Ile Ile Ala Asn Gly 
465                 470                 475                 480 


Phe Pro Asn Pro Arg Glu Val Glu Ser Trp Tyr Leu Lys Ala Leu Glu 
                485                 490                 495     


Thr Cys Ser Ile Asn Asn Gln Met Leu Ala Ala Glu Pro Leu Leu Ser 
            500                 505                 510         


His Met Gln Met Val Thr Glu 
        515                 


<210>  2545
<211>  468
<212>  PRT
<213>  Homo Sapiens

<400>  2545

Gly Lys Val Leu Val Trp Pro Cys Asp Met Ser His Trp Leu Asn Val 
1               5                   10                  15      


Lys Val Ile Leu Glu Glu Leu Ile Val Arg Gly His Glu Val Thr Val 
            20                  25                  30          


Leu Thr His Ser Lys Pro Ser Leu Ile Asp Tyr Arg Lys Pro Ser Ala 
        35                  40                  45              


Leu Lys Phe Glu Val Val His Met Pro Gln Asp Arg Thr Glu Glu Asn 
    50                  55                  60                  


Glu Ile Phe Val Asp Leu Ala Leu Asn Val Leu Pro Gly Leu Ser Thr 
65                  70                  75                  80  


Trp Gln Ser Val Ile Lys Leu Asn Asp Phe Phe Val Glu Ile Arg Gly 
                85                  90                  95      


Thr Leu Lys Met Met Cys Glu Ser Phe Ile Tyr Asn Gln Thr Leu Met 
            100                 105                 110         


Lys Lys Leu Gln Glu Thr Asn Tyr Asp Val Met Leu Ile Asp Pro Val 
        115                 120                 125             


Ile Pro Cys Gly Asp Leu Met Ala Glu Leu Leu Ala Val Pro Phe Val 
    130                 135                 140                 


Leu Thr Leu Arg Ile Ser Val Gly Gly Asn Met Glu Arg Ser Cys Gly 
145                 150                 155                 160 


Lys Leu Pro Ala Pro Leu Ser Tyr Val Pro Val Pro Met Thr Gly Leu 
                165                 170                 175     


Thr Asp Arg Met Thr Phe Leu Glu Arg Val Lys Asn Ser Met Leu Ser 
            180                 185                 190         


Val Leu Phe His Phe Trp Ile Gln Asp Tyr Asp Tyr His Phe Trp Glu 
        195                 200                 205             


Glu Phe Tyr Ser Lys Ala Leu Gly Arg Pro Thr Thr Leu Cys Glu Thr 
    210                 215                 220                 


Val Gly Lys Ala Glu Ile Trp Leu Ile Arg Thr Tyr Trp Asp Phe Glu 
225                 230                 235                 240 


Phe Pro Gln Pro Tyr Gln Pro Asn Phe Glu Phe Val Gly Gly Leu His 
                245                 250                 255     


Cys Lys Pro Ala Lys Ala Leu Pro Lys Glu Met Glu Asn Phe Val Gln 
            260                 265                 270         


Ser Ser Gly Glu Asp Gly Ile Val Val Phe Ser Leu Gly Ser Leu Phe 
        275                 280                 285             


Gln Asn Val Thr Glu Glu Lys Ala Asn Ile Ile Ala Ser Ala Leu Ala 
    290                 295                 300                 


Gln Ile Pro Gln Lys Val Leu Trp Arg Tyr Lys Gly Lys Lys Pro Ser 
305                 310                 315                 320 


Thr Leu Gly Ala Asn Thr Arg Leu Tyr Asp Trp Ile Pro Gln Asn Asp 
                325                 330                 335     


Leu Leu Gly His Pro Lys Thr Lys Ala Phe Ile Thr His Gly Gly Met 
            340                 345                 350         


Asn Gly Ile Tyr Glu Ala Ile Tyr His Gly Val Pro Met Val Gly Val 
        355                 360                 365             


Pro Ile Phe Gly Asp Gln Leu Asp Asn Ile Ala His Met Lys Ala Lys 
    370                 375                 380                 


Gly Ala Ala Val Glu Ile Asn Phe Lys Thr Met Thr Ser Glu Asp Leu 
385                 390                 395                 400 


Leu Arg Ala Leu Arg Thr Val Ile Thr Asp Ser Ser Tyr Lys Glu Asn 
                405                 410                 415     


Ala Met Arg Leu Ser Arg Ile His His Asp Gln Pro Val Lys Pro Leu 
            420                 425                 430         


Asp Arg Ala Val Phe Trp Ile Glu Phe Val Met Arg His Lys Gly Ala 
        435                 440                 445             


Lys His Leu Arg Ser Ala Ala His Asp Leu Thr Trp Phe Gln His Tyr 
    450                 455                 460                 


Ser Ile Asp Val 
465             


<210>  2546
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2546

Gln Gly Gly Gln Val Asp Cys Gly Glu Phe Gln Asp Thr Lys Val Tyr 
1               5                   10                  15      


Cys Thr Arg Glu Ser Asn Pro His Cys Gly Ser Asp Gly Gln Thr Tyr 
            20                  25                  30          


Gly Asn Lys Cys Ala Phe Cys Lys Ala Ile Val Lys Ser Gly Gly Lys 
        35                  40                  45              


Ile Ser Leu Lys His Pro Gly Lys Cys 
    50                  55          


<210>  2547
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  2547

Lys Ile Tyr Thr Arg Cys Lys Leu Ala Lys Ile Phe Ser Arg Ala Gly 
1               5                   10                  15      


Leu Asp Asn Tyr Trp Gly Phe Ser Leu Gly Asn Trp Ile Cys Met Ala 
            20                  25                  30          


Tyr Tyr Glu Ser Gly Tyr Asn Thr Thr Ala Pro Thr Val Leu Asp Asp 
        35                  40                  45              


Gly Ser Ile Asp Tyr Gly Ile Phe Gln Ile Asn Ser Phe Ala Trp Cys 
    50                  55                  60                  


Arg Arg Gly Lys Leu Lys Glu Asn Asn His Cys His Val Ala Cys Ser 
65                  70                  75                  80  


Ala Leu Ile Thr Asp Asp Leu Thr Asp Ala Ile Ile Cys Ala Arg Lys 
                85                  90                  95      


Ile Val Lys Glu Thr Gln Gly Met Asn Tyr Trp Gln Gly Trp Lys Lys 
            100                 105                 110         


His Cys Glu Gly Arg Asp Leu Ser Glu Trp Lys Lys Gly Cys Glu Val 
        115                 120                 125             


Ser 
    


<210>  2548
<211>  397
<212>  PRT
<213>  Homo Sapiens

<400>  2548

Arg Arg Lys Leu Leu Val Phe Leu Leu Asp Gly Phe Arg Ser Asp Tyr 
1               5                   10                  15      


Ile Ser Asp Glu Ala Leu Glu Ser Leu Pro Gly Phe Lys Glu Ile Val 
            20                  25                  30          


Ser Arg Gly Val Lys Val Asp Tyr Leu Thr Pro Asp Phe Pro Ser Leu 
        35                  40                  45              


Ser Tyr Pro Asn Tyr Tyr Thr Leu Met Thr Gly Arg His Cys Glu Val 
    50                  55                  60                  


His Gln Met Ile Gly Asn Tyr Met Trp Asp Pro Thr Thr Asn Lys Ser 
65                  70                  75                  80  


Phe Asp Ile Gly Val Asn Lys Asp Ser Leu Met Pro Leu Trp Trp Asn 
                85                  90                  95      


Gly Ser Glu Pro Leu Trp Val Thr Leu Thr Lys Ala Lys Arg Lys Val 
            100                 105                 110         


Tyr Met Tyr Tyr Trp Pro Gly Cys Glu Val Glu Ile Leu Gly Val Arg 
        115                 120                 125             


Pro Thr Tyr Cys Leu Glu Tyr Lys Asn Val Pro Thr Asp Ile Asn Phe 
    130                 135                 140                 


Ala Asn Ala Val Ser Asp Ala Leu Asp Ser Phe Lys Ser Gly Arg Ala 
145                 150                 155                 160 


Asp Leu Ala Ala Ile Tyr His Glu Arg Ile Asp Val Glu Gly His His 
                165                 170                 175     


Tyr Gly Pro Ala Ser Pro Gln Arg Lys Asp Ala Leu Lys Ala Val Asp 
            180                 185                 190         


Thr Val Leu Lys Tyr Met Thr Lys Trp Ile Gln Glu Arg Gly Leu Gln 
        195                 200                 205             


Asp Arg Leu Asn Val Ile Ile Phe Ser Asp His Gly Met Thr Asp Ile 
    210                 215                 220                 


Phe Trp Met Asp Lys Val Ile Glu Leu Asn Lys Tyr Ile Ser Leu Asn 
225                 230                 235                 240 


Asp Leu Gln Gln Val Lys Asp Arg Gly Pro Val Val Ser Leu Trp Pro 
                245                 250                 255     


Ala Pro Gly Lys His Ser Glu Ile Tyr Asn Lys Leu Ser Thr Val Glu 
            260                 265                 270         


His Met Thr Val Tyr Glu Lys Glu Ala Ile Pro Ser Arg Phe Tyr Tyr 
        275                 280                 285             


Lys Lys Gly Lys Phe Val Ser Pro Leu Thr Leu Val Ala Asp Glu Gly 
    290                 295                 300                 


Trp Phe Ile Thr Glu Asn Arg Glu Met Leu Pro Phe Trp Met Asn Ser 
305                 310                 315                 320 


Thr Gly Arg Arg Glu Gly Trp Gln Arg Gly Trp His Gly Tyr Asp Asn 
                325                 330                 335     


Glu Leu Met Asp Met Arg Gly Ile Phe Leu Ala Phe Gly Pro Asp Phe 
            340                 345                 350         


Lys Ser Asn Phe Arg Ala Ala Pro Ile Arg Ser Val Asp Val Tyr Asn 
        355                 360                 365             


Val Met Cys Asn Val Val Gly Ile Thr Pro Leu Pro Asn Asn Gly Ser 
    370                 375                 380                 


Trp Ser Arg Val Met Cys Met Leu Lys Gly Arg Ala Ser 
385                 390                 395         


<210>  2549
<211>  268
<212>  PRT
<213>  Homo Sapiens

<400>  2549

Gln Pro Phe Ser Pro Leu Ala Pro Glu Pro Val Leu Ser Gly Ala His 
1               5                   10                  15      


Thr Trp Arg Ser Leu Ile His His Ile Arg Leu Met Ser Leu Pro Ile 
            20                  25                  30          


Ala Lys Lys Tyr Met Ser Glu Asn Lys Gly Val Pro Leu His Gly Gly 
        35                  40                  45              


Asp Glu Asp Arg Pro Phe Pro Asp Phe Asp Pro Trp Trp Thr Asn Asp 
    50                  55                  60                  


Cys Glu Gln Asn Glu Ser Glu Pro Ile Pro Ala Asn Cys Thr Gly Cys 
65                  70                  75                  80  


Ala Gln Lys His Leu Lys Val Met Leu Leu Glu Asp Ala Pro Arg Lys 
                85                  90                  95      


Phe Glu Arg Leu His Pro Leu Val Ile Lys Thr Gly Lys Pro Leu Leu 
            100                 105                 110         


Glu Glu Glu Ile Gln His Phe Leu Cys Gln Tyr Pro Glu Ala Thr Glu 
        115                 120                 125             


Gly Phe Ser Glu Gly Phe Phe Ala Lys Trp Trp Arg Cys Phe Pro Glu 
    130                 135                 140                 


Arg Trp Phe Pro Phe Pro Tyr Pro Trp Arg Arg Pro Leu Asn Arg Ser 
145                 150                 155                 160 


Gln Met Leu Arg Glu Leu Phe Pro Val Phe Thr His Leu Pro Phe Pro 
                165                 170                 175     


Lys Asp Ala Ser Leu Asn Lys Cys Ser Phe Leu His Pro Glu Pro Val 
            180                 185                 190         


Val Gly Ser Lys Met His Lys Met Pro Asp Leu Phe Ile Ile Gly Ser 
        195                 200                 205             


Gly Glu Ala Met Leu Gln Leu Ile Pro Pro Phe Gln Cys Arg Arg His 
    210                 215                 220                 


Cys Gln Ser Val Ala Met Pro Ile Glu Pro Gly Asp Ile Gly Tyr Val 
225                 230                 235                 240 


Asp Thr Thr His Trp Lys Val Tyr Val Ile Ala Arg Gly Val Gln Pro 
                245                 250                 255     


Leu Val Ile Cys Asp Gly Thr Ala Phe Ser Glu Leu 
            260                 265             


<210>  2550
<211>  412
<212>  PRT
<213>  Homo Sapiens

<400>  2550

Ala Pro Val Gln Ser Gln Gly Ser Gln Asn Lys Leu Leu Leu Val Ser 
1               5                   10                  15      


Phe Asp Gly Phe Arg Trp Asn Tyr Asp Gln Asp Val Asp Thr Pro Asn 
            20                  25                  30          


Leu Asp Ala Met Ala Arg Asp Gly Val Lys Ala Arg Tyr Met Thr Pro 
        35                  40                  45              


Ala Phe Val Thr Met Thr Ser Pro Cys His Phe Thr Leu Val Thr Gly 
    50                  55                  60                  


Lys Tyr Ile Glu Asn His Gly Val Val His Asn Met Tyr Tyr Asn Thr 
65                  70                  75                  80  


Thr Ser Lys Val Lys Leu Pro Tyr His Ala Thr Leu Gly Ile Gln Arg 
                85                  90                  95      


Trp Trp Asp Asn Gly Ser Val Pro Ile Trp Ile Thr Ala Gln Arg Gln 
            100                 105                 110         


Gly Leu Arg Ala Gly Ser Phe Phe Tyr Pro Gly Gly Asn Val Thr Tyr 
        115                 120                 125             


Gln Gly Val Ala Val Thr Arg Ser Arg Lys Glu Gly Ile Ala His Asn 
    130                 135                 140                 


Tyr Lys Asn Glu Thr Glu Trp Arg Ala Asn Ile Asp Thr Val Met Ala 
145                 150                 155                 160 


Trp Phe Thr Glu Glu Asp Leu Asp Leu Val Thr Leu Tyr Phe Gly Glu 
                165                 170                 175     


Pro Asp Ser Thr Gly His Arg Tyr Gly Pro Glu Ser Pro Glu Arg Arg 
            180                 185                 190         


Glu Met Val Arg Gln Val Asp Arg Thr Val Gly Tyr Leu Arg Glu Ser 
        195                 200                 205             


Ile Ala Arg Asn His Leu Thr Asp Arg Leu Asn Leu Ile Ile Thr Ser 
    210                 215                 220                 


Asp His Gly Met Thr Thr Val Asp Lys Arg Ala Gly Asp Leu Val Glu 
225                 230                 235                 240 


Phe His Lys Phe Pro Asn Phe Thr Phe Arg Asp Ile Glu Phe Glu Leu 
                245                 250                 255     


Leu Asp Tyr Gly Pro Asn Gly Met Leu Leu Pro Lys Glu Gly Arg Leu 
            260                 265                 270         


Glu Lys Val Tyr Asp Ala Leu Lys Asp Ala His Pro Lys Leu His Val 
        275                 280                 285             


Tyr Lys Lys Glu Ala Phe Pro Glu Ala Phe His Tyr Ala Asn Asn Pro 
    290                 295                 300                 


Arg Val Thr Pro Leu Leu Met Tyr Ser Asp Leu Gly Tyr Val Ile His 
305                 310                 315                 320 


Gly Arg Ile Asn Val Gln Phe Asn Asn Gly Glu His Gly Phe Asp Asn 
                325                 330                 335     


Lys Asp Met Asp Met Lys Thr Ile Phe Arg Ala Val Gly Pro Ser Phe 
            340                 345                 350         


Arg Ala Gly Leu Glu Val Glu Pro Phe Glu Ser Val His Val Tyr Glu 
        355                 360                 365             


Leu Met Cys Arg Leu Leu Gly Ile Val Pro Glu Ala Asn Asp Gly His 
    370                 375                 380                 


Leu Ala Thr Leu Leu Pro Met Leu His Thr Glu Ser Ala Leu Pro Pro 
385                 390                 395                 400 


Asp Gly Arg Pro Thr Leu Leu Pro Lys Gly Arg Ser 
                405                 410         


<210>  2551
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  2551

Glu Val Leu Leu Gln Pro Asp Phe Asn Ala Glu Lys Phe Ser Gly Leu 
1               5                   10                  15      


Trp Tyr Val Val Ser Met Ala Ser Asp Cys Arg Val Phe Leu Gly Lys 
            20                  25                  30          


Lys Asp His Leu Ser Met Ser Thr Arg Ala Ile Arg Pro Thr Glu Glu 
        35                  40                  45              


Gly Gly Leu His Val His Met Glu Phe Pro Gly Ala Asp Gly Cys Asn 
    50                  55                  60                  


Gln Val Asp Ala Glu Tyr Leu Lys Val Gly Ser Glu Gly His Phe Arg 
65                  70                  75                  80  


Val Pro Ala Leu Gly Tyr Leu Asp Val Arg Ile Val Asp Thr Asp Tyr 
                85                  90                  95      


Ser Ser Phe Ala Val Leu Tyr Ile Tyr Lys Glu Leu Glu Gly Ala Leu 
            100                 105                 110         


Ser Thr Met Val Gln Leu Tyr Ser Arg Thr Gln Asp Val Ser Pro Gln 
        115                 120                 125             


Ala Leu Lys Ser Phe Gln Asp Phe Tyr Pro Thr Leu Gly Leu Pro Lys 
    130                 135                 140                 


Asp Met Met Val Met Leu Pro Gln Ser Asp Ala Cys Asn Pro Glu Ser 
145                 150                 155                 160 


Lys Glu Ala Pro 
                


<210>  2552
<211>  542
<212>  PRT
<213>  Homo Sapiens

<400>  2552

Thr Gly Pro Glu Val Ala Gln Pro Glu Val Asp Thr Thr Leu Gly Arg 
1               5                   10                  15      


Val Arg Gly Arg Gln Val Gly Val Lys Gly Thr Asp Arg Leu Val Asn 
            20                  25                  30          


Val Phe Leu Gly Ile Pro Phe Ala Gln Pro Pro Leu Gly Pro Asp Arg 
        35                  40                  45              


Phe Ser Ala Pro His Pro Ala Gln Pro Trp Glu Gly Val Arg Asp Ala 
    50                  55                  60                  


Ser Thr Ala Pro Pro Met Cys Leu Gln Asp Val Glu Ser Met Asn Ser 
65                  70                  75                  80  


Ser Arg Phe Val Leu Asn Gly Lys Gln Gln Ile Phe Ser Val Ser Glu 
                85                  90                  95      


Asp Cys Leu Val Leu Asn Val Tyr Ser Pro Ala Glu Val Pro Ala Gly 
            100                 105                 110         


Ser Gly Arg Pro Val Met Val Trp Val His Gly Gly Ala Leu Ile Thr 
        115                 120                 125             


Gly Ala Ala Thr Ser Tyr Asp Gly Ser Ala Leu Ala Ala Tyr Gly Asp 
    130                 135                 140                 


Val Val Val Val Thr Val Gln Tyr Arg Leu Gly Val Leu Gly Phe Phe 
145                 150                 155                 160 


Ser Thr Gly Asp Glu His Ala Pro Gly Asn Gln Gly Phe Leu Asp Val 
                165                 170                 175     


Val Ala Ala Leu Arg Trp Val Gln Glu Asn Ile Ala Pro Phe Gly Gly 
            180                 185                 190         


Asp Leu Asn Cys Val Thr Val Phe Gly Gly Ser Ala Gly Gly Ser Ile 
        195                 200                 205             


Ile Ser Gly Leu Val Leu Ser Pro Val Ala Ala Gly Leu Phe His Arg 
    210                 215                 220                 


Ala Ile Thr Gln Ser Gly Val Ile Thr Thr Pro Gly Ile Ile Asp Ser 
225                 230                 235                 240 


His Pro Trp Pro Leu Ala Gln Lys Ile Ala Asn Thr Leu Ala Cys Ser 
                245                 250                 255     


Ser Ser Ser Pro Ala Glu Met Val Gln Cys Leu Gln Gln Lys Glu Gly 
            260                 265                 270         


Glu Glu Leu Val Leu Ser Lys Lys Leu Lys Asn Thr Ile Tyr Pro Leu 
        275                 280                 285             


Thr Val Asp Gly Thr Val Phe Pro Lys Ser Pro Lys Glu Leu Leu Lys 
    290                 295                 300                 


Glu Lys Pro Phe His Ser Val Pro Phe Leu Met Gly Val Asn Asn His 
305                 310                 315                 320 


Glu Phe Ser Trp Leu Ile Pro Arg Gly Trp Gly Leu Leu Asp Thr Met 
                325                 330                 335     


Glu Gln Met Ser Arg Glu Asp Met Leu Ala Ile Ser Thr Pro Val Leu 
            340                 345                 350         


Thr Ser Leu Asp Val Pro Pro Glu Met Met Pro Thr Val Ile Asp Glu 
        355                 360                 365             


Tyr Leu Gly Ser Asn Ser Asp Ala Gln Ala Lys Cys Gln Ala Phe Gln 
    370                 375                 380                 


Glu Phe Met Gly Asp Val Phe Ile Asn Val Pro Thr Val Ser Phe Ser 
385                 390                 395                 400 


Arg Tyr Leu Arg Asp Ser Gly Ser Pro Val Phe Phe Tyr Glu Phe Gln 
                405                 410                 415     


His Arg Pro Ser Ser Phe Ala Lys Ile Lys Pro Ala Trp Val Lys Ala 
            420                 425                 430         


Asp His Gly Ala Glu Gly Ala Phe Val Phe Gly Gly Pro Phe Leu Met 
        435                 440                 445             


Asp Glu Ser Ser Arg Leu Glu Ala Thr Glu Glu Glu Lys Gln Leu Ser 
    450                 455                 460                 


Leu Thr Met Met Ala Gln Trp Thr His Phe Ala Arg Thr Gly Asp Pro 
465                 470                 475                 480 


Asn Ser Lys Ala Leu Pro Pro Trp Pro Gln Phe Asn Gln Ala Glu Gln 
                485                 490                 495     


Tyr Leu Glu Ile Asn Pro Val Pro Arg Ala Gly Gln Lys Phe Arg Glu 
            500                 505                 510         


Ala Trp Met Gln Phe Trp Ser Glu Thr Leu Pro Ser Lys Ile Gln Gln 
        515                 520                 525             


Trp His Gln Lys Gln Lys Asn Arg Lys Ala Gln Glu Asp Leu 
    530                 535                 540         


<210>  2553
<211>  514
<212>  PRT
<213>  Homo Sapiens

<400>  2553

Glu Gln Arg Arg Arg Ala Ala Lys Ala Pro Asn Val Val Leu Val Val 
1               5                   10                  15      


Ser Asp Ser Phe Asp Gly Arg Leu Thr Phe His Pro Gly Ser Gln Val 
            20                  25                  30          


Val Lys Leu Pro Phe Ile Asn Phe Met Lys Thr Arg Gly Thr Ser Phe 
        35                  40                  45              


Leu Asn Ala Tyr Thr Asn Ser Pro Ile Cys Cys Pro Ser Arg Ala Ala 
    50                  55                  60                  


Met Trp Ser Gly Leu Phe Thr His Leu Thr Glu Ser Trp Asn Asn Phe 
65                  70                  75                  80  


Lys Gly Leu Asp Pro Asn Tyr Thr Thr Trp Met Asp Val Met Glu Arg 
                85                  90                  95      


His Gly Tyr Arg Thr Gln Lys Phe Gly Lys Leu Asp Tyr Thr Ser Gly 
            100                 105                 110         


His His Ser Ile Ser Asn Arg Val Glu Ala Trp Thr Arg Asp Val Ala 
        115                 120                 125             


Phe Leu Leu Arg Gln Glu Gly Arg Pro Met Val Asn Leu Ile Arg Asn 
    130                 135                 140                 


Arg Thr Lys Val Arg Val Met Glu Arg Asp Trp Gln Asn Thr Asp Lys 
145                 150                 155                 160 


Ala Val Asn Trp Leu Arg Lys Glu Ala Ile Asn Tyr Thr Glu Pro Phe 
                165                 170                 175     


Val Ile Tyr Leu Gly Leu Asn Leu Pro His Pro Tyr Pro Ser Pro Ser 
            180                 185                 190         


Ser Gly Glu Asn Phe Gly Ser Ser Thr Phe His Thr Ser Leu Tyr Trp 
        195                 200                 205             


Leu Glu Lys Val Ser His Asp Ala Ile Lys Ile Pro Lys Trp Ser Pro 
    210                 215                 220                 


Leu Ser Glu Met His Pro Val Asp Tyr Tyr Ser Ser Tyr Thr Lys Asn 
225                 230                 235                 240 


Cys Thr Gly Arg Phe Thr Lys Lys Glu Ile Lys Asn Ile Arg Ala Phe 
                245                 250                 255     


Tyr Tyr Ala Met Cys Ala Glu Thr Asp Ala Met Leu Gly Glu Ile Ile 
            260                 265                 270         


Leu Ala Leu His Gln Leu Asp Leu Leu Gln Lys Thr Ile Val Ile Tyr 
        275                 280                 285             


Ser Ser Asp His Gly Glu Leu Ala Met Glu His Arg Gln Phe Tyr Lys 
    290                 295                 300                 


Met Ser Met Tyr Glu Ala Ser Ala His Val Pro Leu Leu Met Met Gly 
305                 310                 315                 320 


Pro Gly Ile Lys Ala Gly Leu Gln Val Ser Asn Val Val Ser Leu Val 
                325                 330                 335     


Asp Ile Tyr Pro Thr Met Leu Asp Ile Ala Gly Ile Pro Leu Pro Gln 
            340                 345                 350         


Asn Leu Ser Gly Tyr Ser Leu Leu Pro Leu Ser Ser Glu Thr Phe Lys 
        355                 360                 365             


Asn Glu His Lys Val Lys Asn Leu His Pro Pro Trp Ile Leu Ser Glu 
    370                 375                 380                 


Phe His Gly Cys Asn Val Asn Ala Ser Thr Tyr Met Leu Arg Thr Asn 
385                 390                 395                 400 


His Trp Lys Tyr Ile Ala Tyr Ser Asp Gly Ala Ser Ile Leu Pro Gln 
                405                 410                 415     


Leu Phe Asp Leu Ser Ser Asp Pro Asp Glu Leu Thr Asn Val Ala Val 
            420                 425                 430         


Lys Phe Pro Glu Ile Thr Tyr Ser Leu Asp Gln Lys Leu His Ser Ile 
        435                 440                 445             


Ile Asn Tyr Pro Lys Val Ser Ala Ser Val His Gln Tyr Asn Lys Glu 
    450                 455                 460                 


Gln Phe Ile Lys Trp Lys Gln Ser Ile Gly Gln Asn Tyr Ser Asn Val 
465                 470                 475                 480 


Ile Ala Asn Leu Arg Trp His Gln Asp Trp Gln Lys Glu Pro Arg Lys 
                485                 490                 495     


Tyr Glu Asn Ala Ile Asp Gln Trp Leu Lys Thr His Met Asn Pro Arg 
            500                 505                 510         


Ala Val 
        


<210>  2554
<211>  252
<212>  PRT
<213>  Homo Sapiens

<400>  2554

Ala Gln Ile Ile Gly Gly His Glu Val Thr Pro His Ser Arg Pro Tyr 
1               5                   10                  15      


Met Ala Ser Val Arg Phe Gly Gly Gln His His Cys Gly Gly Phe Leu 
            20                  25                  30          


Leu Arg Ala Arg Trp Val Val Ser Ala Ala His Cys Phe Ser His Arg 
        35                  40                  45              


Asp Leu Arg Thr Gly Leu Val Val Leu Gly Ala His Val Leu Ser Thr 
    50                  55                  60                  


Ala Glu Pro Thr Gln Gln Val Phe Gly Ile Asp Ala Leu Thr Thr His 
65                  70                  75                  80  


Pro Asp Tyr His Pro Met Thr His Ala Asn Asp Ile Cys Leu Leu Arg 
                85                  90                  95      


Leu Asn Gly Ser Ala Val Leu Gly Pro Ala Val Gly Leu Leu Arg Leu 
            100                 105                 110         


Pro Gly Arg Arg Ala Arg Pro Pro Thr Ala Gly Thr Arg Cys Arg Val 
        115                 120                 125             


Ala Gly Trp Gly Phe Val Ser Asp Phe Glu Glu Leu Pro Pro Gly Leu 
    130                 135                 140                 


Met Glu Ala Lys Val Arg Val Leu Asp Pro Asp Val Cys Asn Ser Ser 
145                 150                 155                 160 


Trp Lys Gly His Leu Thr Leu Thr Met Leu Cys Thr Arg Ser Gly Asp 
                165                 170                 175     


Ser His Arg Arg Gly Phe Cys Ser Ala Asp Ser Gly Gly Pro Leu Val 
            180                 185                 190         


Cys Arg Asn Arg Ala His Gly Leu Val Ser Phe Ser Gly Leu Trp Cys 
        195                 200                 205             


Gly Asp Pro Lys Thr Pro Asp Val Tyr Thr Gln Val Ser Ala Phe Val 
    210                 215                 220                 


Ala Trp Ile Trp Asp Val Val Arg Arg Ser Ser Pro Gln Pro Gly Pro 
225                 230                 235                 240 


Leu Pro Gly Thr Thr Arg Pro Pro Gly Glu Ala Ala 
                245                 250         


<210>  2555
<211>  374
<212>  PRT
<213>  Homo Sapiens

<400>  2555

Pro Ala Met Val His Tyr Ile Tyr Gln Arg Phe Arg Val Leu Glu Gln 
1               5                   10                  15      


Gly Leu Glu Lys Cys Thr Gln Ala Thr Arg Ala Tyr Ile Gln Glu Phe 
            20                  25                  30          


Gln Glu Phe Ser Lys Asn Ile Ser Val Met Leu Gly Arg Cys Gln Thr 
        35                  40                  45              


Tyr Thr Ser Glu Tyr Lys Ser Ala Val Gly Asn Leu Ala Leu Arg Val 
    50                  55                  60                  


Glu Arg Ala Gln Arg Glu Ile Asp Tyr Ile Gln Tyr Leu Arg Glu Ala 
65                  70                  75                  80  


Asp Glu Cys Ile Val Ser Glu Asp Lys Thr Leu Ala Glu Met Leu Leu 
                85                  90                  95      


Gln Glu Ala Glu Glu Glu Lys Lys Ile Arg Thr Leu Leu Asn Ala Ser 
            100                 105                 110         


Cys Asp Asn Met Leu Met Gly Ile Lys Ser Leu Lys Ile Val Lys Lys 
        115                 120                 125             


Met Met Asp Thr His Gly Ser Trp Met Lys Asp Ala Val Tyr Asn Ser 
    130                 135                 140                 


Pro Lys Val Tyr Leu Leu Ile Gly Ser Arg Asn Asn Thr Val Trp Glu 
145                 150                 155                 160 


Phe Ala Asn Ile Arg Ala Phe Met Glu Asp Asn Thr Lys Pro Ala Pro 
                165                 170                 175     


Arg Lys Gln Ile Leu Thr Leu Ser Trp Gln Gly Thr Gly Gln Val Ile 
            180                 185                 190         


Tyr Lys Gly Phe Leu Phe Phe His Asn Gln Ala Thr Ser Asn Glu Ile 
        195                 200                 205             


Ile Lys Tyr Asn Leu Gln Lys Arg Thr Val Glu Asp Arg Met Leu Leu 
    210                 215                 220                 


Pro Gly Gly Val Gly Arg Ala Leu Val Tyr Gln His Ser Pro Ser Thr 
225                 230                 235                 240 


Tyr Ile Asp Leu Ala Val Asp Glu His Gly Leu Trp Ala Ile His Ser 
                245                 250                 255     


Gly Pro Gly Thr His Ser His Leu Val Leu Thr Lys Ile Glu Pro Gly 
            260                 265                 270         


Thr Leu Gly Val Glu His Ser Trp Asp Thr Pro Cys Arg Ser Gln Asp 
        275                 280                 285             


Ala Glu Ala Ser Phe Leu Leu Cys Gly Val Leu Tyr Val Val Tyr Ser 
    290                 295                 300                 


Thr Gly Gly Gln Gly Pro His Arg Ile Thr Cys Ile Tyr Asp Pro Leu 
305                 310                 315                 320 


Gly Thr Ile Ser Glu Glu Asp Leu Pro Asn Leu Phe Phe Pro Lys Arg 
                325                 330                 335     


Pro Arg Ser His Ser Met Ile His Tyr Asn Pro Arg Asp Lys Gln Leu 
            340                 345                 350         


Tyr Ala Trp Asn Glu Gly Asn Gln Ile Ile Tyr Lys Leu Gln Thr Lys 
        355                 360                 365             


Arg Lys Leu Pro Leu Lys 
    370                 


<210>  2556
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  2556

Asp Leu Gly Asp Val Gly Pro Pro Ile Pro Ser Pro Gly Phe Ser Ser 
1               5                   10                  15      


Phe Pro Gly Val Asp Ser Ser Ser Ser Phe Ser Ser Ser Ser Arg Ser 
            20                  25                  30          


Gly Ser Ser Ser Ser Arg Ser Leu Gly Ser Gly Gly Ser Val Ser Gln 
        35                  40                  45              


Leu Phe Ser Asn Phe Thr Gly Ser Val Asp Asp Arg Gly Thr Cys Gln 
    50                  55                  60                  


Cys Ser Val Ser Leu Pro Asp Thr Thr Phe Pro Val Asp Arg Val Glu 
65                  70                  75                  80  


Arg Leu Glu Phe Thr Ala His Val Leu Ser Gln Lys Phe Glu Lys Glu 
                85                  90                  95      


Leu Ser Lys Val Arg Glu Tyr Val Gln Leu Ile Ser Val Tyr Glu Lys 
            100                 105                 110         


Lys Leu Leu Asn Leu Thr Val Arg Ile Asp Ile Met Glu Lys Asp Thr 
        115                 120                 125             


Ile Ser Tyr Thr Glu Leu Asp Phe Glu Leu Ile Lys Val Glu Val Lys 
    130                 135                 140                 


Glu Met Glu Lys Leu Val Ile Gln Leu Lys Glu Ser Phe Gly Gly Ser 
145                 150                 155                 160 


Ser Glu Ile Val Asp Gln Leu Glu Val Glu Ile Arg Asn Met Thr Leu 
                165                 170                 175     


Leu Val Glu Lys Leu Glu Thr Leu Asp Lys Asn Asn Val Leu Ala Ile 
            180                 185                 190         


Arg Arg Glu Ile Val Ala Leu Lys Thr Lys Leu Lys Glu Cys Glu Ala 
        195                 200                 205             


Ser Lys Asp Gln Asn Thr Pro Val Val His Pro Pro Pro Thr Pro Gly 
    210                 215                 220                 


Ser Cys Gly His Gly Gly Val Val Asn Ile Ser Lys Pro Ser Val Val 
225                 230                 235                 240 


Gln Leu Asn Trp Arg Gly Phe Ser Tyr Leu Tyr Gly Ala Trp Gly Arg 
                245                 250                 255     


Asp Tyr Ser Pro Gln His Pro Asn Lys Gly Leu Tyr Trp Val Ala Pro 
            260                 265                 270         


Leu Asn Thr Asp Gly Arg Leu Leu Glu Tyr Tyr Arg Leu Tyr Asn Thr 
        275                 280                 285             


Leu Asp Asp Leu Leu Leu Tyr Ile Asn Ala Arg Glu Leu Arg Ile Thr 
    290                 295                 300                 


Tyr Gly Gln Gly Ser Gly Thr Ala Val Tyr Asn Asn Asn Met Tyr Val 
305                 310                 315                 320 


Asn Met Tyr Asn Thr Gly Asn Ile Ala Arg Val Asn Leu Thr Thr Asn 
                325                 330                 335     


Thr Ile Ala Val Thr Gln Thr Leu Pro Asn Ala Ala Tyr Asn Asn Arg 
            340                 345                 350         


Phe Ser Tyr Ala Asn Val Ala Trp Gln Asp Ile Asp Phe Ala Val Asp 
        355                 360                 365             


Glu Asn Gly Leu Trp Val Ile Tyr Ser Thr Glu Ala Ser Thr Gly Asn 
    370                 375                 380                 


Met Val Ile Ser Lys Leu Asn Asp Thr Thr Leu Gln Val Leu Asn Thr 
385                 390                 395                 400 


Trp Tyr Thr Lys Gln Tyr Lys Pro Ser Ala Ser Asn Ala Phe Met Val 
                405                 410                 415     


Cys Gly Val Leu Tyr Ala Thr Arg Thr Met Asn Thr Arg Thr Glu Glu 
            420                 425                 430         


Ile Phe Tyr Tyr Tyr Asp Thr Asn Thr Gly Lys Glu Gly Lys Leu Asp 
        435                 440                 445             


Ile Val Met His Lys Met Gln Glu Lys Val Gln Ser Ile Asn Tyr Asn 
    450                 455                 460                 


Pro Phe Asp Gln Lys Leu Tyr Val Tyr Asn Asp Gly Tyr Leu Leu Asn 
465                 470                 475                 480 


Tyr Asp Leu Ser Val Leu Gln Lys Pro Gln 
                485                 490 


<210>  2557
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  2557

Asp Asp Val Pro Gln Glu Pro Val Pro Thr Leu Trp Asn Glu Pro Ala 
1               5                   10                  15      


Glu Leu Pro Ser Gly Glu Gly Pro Val Glu Ser Thr Ser Pro Gly Arg 
            20                  25                  30          


Glu Pro Val Asp Thr Gly Pro Pro Ala Pro Thr Val Ala Pro Gly Pro 
        35                  40                  45              


Glu Asp Ser Thr Ala Gln Glu Arg Leu Asp Gln Gly Gly Gly Ser Leu 
    50                  55                  60                  


Gly Pro Gly Ala 
65              


<210>  2558
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  2558

Leu Pro Gln Leu Lys Pro Ala Leu Gly Leu Pro Pro Thr Lys Leu Ala 
1               5                   10                  15      


Pro Asp Gln Gly Thr Leu Pro Asn Gln Gln Gln Ser Asn Gln Val Phe 
            20                  25                  30          


Pro Ser Leu Ser Leu Ile Pro Leu Thr Gln Met Leu Thr Leu Gly Pro 
        35                  40                  45              


Asp Leu His Leu Leu Asn Pro Ala Ala Gly Met Thr Pro Gly Thr Gln 
    50                  55                  60                  


Thr His Pro Leu Thr Leu Gly Gly Leu Asn Val Gln Gln Gln Leu His 
65                  70                  75                  80  


Pro His Val Leu Pro Ile Phe Val Thr Gln Leu Gly Ala Gln Gly Thr 
                85                  90                  95      


Ile Leu Ser Ser Glu Glu Leu Pro Gln Ile Phe Thr Ser Leu Ile Ile 
            100                 105                 110         


His Ser Leu Phe Pro Gly Gly Ile Leu Pro Thr Ser Gln Ala Gly Ala 
        115                 120                 125             


Asn Pro Asp Val Gln Asp Gly Ser Leu Pro Ala Gly Gly Ala Gly Val 
    130                 135                 140                 


Asn Pro Ala Thr Gln Gly Thr Pro Ala Gly Arg Leu Pro Thr Pro Ser 
145                 150                 155                 160 


Gly Thr Asp Asp Asp Phe Ala Val Thr Thr Pro Ala Gly Ile Gln Arg 
                165                 170                 175     


Ser Thr His Ala Ile Glu Glu Ala Thr Thr Glu Ser Ala Asn Gly Ile 
            180                 185                 190         


Gln 
    


<210>  2559
<211>  375
<212>  PRT
<213>  Homo Sapiens

<400>  2559

Lys Pro Gly Asp Gln Ile Leu Asp Trp Gln Tyr Gly Val Thr Gln Ala 
1               5                   10                  15      


Phe Pro His Thr Glu Glu Glu Val Glu Val Asp Ser His Ala Tyr Ser 
            20                  25                  30          


His Arg Trp Lys Arg Asn Leu Asp Phe Leu Lys Ala Val Asp Thr Asn 
        35                  40                  45              


Arg Ala Ser Val Gly Gln Asp Ser Pro Glu Pro Arg Ser Phe Thr Asp 
    50                  55                  60                  


Leu Leu Leu Asp Asp Gly Gln Asp Asn Asn Thr Gln Ile Glu Arg Val 
65                  70                  75                  80  


Asn Leu Ser Phe Asp Phe Pro Phe Tyr Gly His Phe Leu Arg Glu Ile 
                85                  90                  95      


Thr Val Ala Thr Gly Gly Phe Ile Tyr Thr Gly Glu Val Val His Arg 
            100                 105                 110         


Met Leu Thr Ala Thr Gln Tyr Ile Ala Pro Leu Met Ala Asn Phe Asp 
        115                 120                 125             


Pro Ser Val Ser Arg Asn Ser Thr Val Arg Tyr Phe Asp Asn Gly Thr 
    130                 135                 140                 


Ala Leu Val Val Gln Trp Asp His Val His Leu Gln Asp Asn Tyr Asn 
145                 150                 155                 160 


Leu Gly Ser Phe Thr Phe Gln Ala Thr Leu Leu Met Asp Gly Arg Ile 
                165                 170                 175     


Ile Phe Gly Tyr Lys Glu Ile Pro Val Leu Val Thr Gln Ile Ser Ser 
            180                 185                 190         


Thr Asn His Pro Val Lys Val Gly Leu Ser Asp Ala Phe Val Val Val 
        195                 200                 205             


His Arg Ile Gln Gln Ile Pro Asn Val Arg Arg Arg Thr Ile Tyr Glu 
    210                 215                 220                 


Tyr His Arg Val Glu Leu Gln Met Ser Lys Ile Thr Asn Ile Ser Ala 
225                 230                 235                 240 


Val Glu Met Thr Pro Leu Pro Thr Cys Leu Gln Phe Asn Arg Cys Gly 
                245                 250                 255     


Pro Cys Val Ser Ser Gln Ile Gly Phe Asn Cys Ser Trp Cys Ser Lys 
            260                 265                 270         


Leu Gln Arg Cys Ser Ser Gly Phe Asp Arg His Arg Gln Asp Trp Val 
        275                 280                 285             


Asp Ser Gly Cys Pro Glu Glu Ser Lys Glu Lys Met Cys Glu Asn Thr 
    290                 295                 300                 


Glu Pro Val Glu Thr Ser Ser Arg Thr Thr Thr Thr Val Gly Ala Thr 
305                 310                 315                 320 


Thr Thr Gln Phe Arg Val Leu Thr Thr Thr Arg Arg Ala Val Thr Ser 
                325                 330                 335     


Gln Phe Pro Thr Ser Leu Pro Thr Glu Asp Asp Thr Lys Ile Ala Leu 
            340                 345                 350         


His Leu Lys Asp Asn Gly Ala Ser Thr Asp Asp Ser Ala Ala Glu Lys 
        355                 360                 365             


Lys Gly Gly Thr Leu His Ala 
    370                 375 


<210>  2560
<211>  299
<212>  PRT
<213>  Homo Sapiens

<400>  2560

Arg Ser Ile Gly Val Val Glu Glu Lys Val Ser Gln Asn Leu Gly Thr 
1               5                   10                  15      


Asn Leu Pro Gln Leu Gly Gln Pro Ser Ser Thr Gly Pro Ser Asn Ser 
            20                  25                  30          


Glu His Pro Gln Pro Ala Leu Asp Pro Arg Ser Asn Asp Leu Ala Arg 
        35                  40                  45              


Val Pro Leu Lys Leu Ser Val Pro Ala Ser Asp Gly Phe Pro Pro Ala 
    50                  55                  60                  


Gly Gly Ser Ala Val Gln Arg Trp Pro Pro Ser Trp Gly Leu Pro Ala 
65                  70                  75                  80  


Met Asp Ser Trp Pro Pro Glu Asp Pro Trp Gln Met Met Ala Ala Ala 
                85                  90                  95      


Ala Glu Asp Arg Leu Gly Glu Ala Leu Pro Glu Glu Leu Ser Tyr Leu 
            100                 105                 110         


Ser Ser Ala Ala Ala Leu Ala Pro Gly Ser Gly Pro Leu Pro Gly Glu 
        115                 120                 125             


Ser Ser Pro Asp Ala Thr Gly Leu Ser Pro Lys Ala Ser Leu Leu His 
    130                 135                 140                 


Gln Asp Ser Glu Ser Arg Arg Leu Pro Arg Ser Asn Ser Leu Gly Ala 
145                 150                 155                 160 


Gly Gly Lys Ile Leu Ser Gln Arg Pro Pro Trp Ser Leu Ile His Arg 
                165                 170                 175     


Val Leu Pro Asp His Pro Trp Gly Thr Leu Asn Pro Ser Val Ser Trp 
            180                 185                 190         


Gly Gly Gly Gly Pro Gly Thr Gly Trp Gly Thr Arg Pro Met Pro His 
        195                 200                 205             


Pro Glu Gly Ile Trp Gly Ile Asn Asn Gln Pro Pro Gly Thr Ser Trp 
    210                 215                 220                 


Gly Asn Ile Asn Arg Tyr Pro Gly Gly Ser Trp Gly Asn Ile Asn Arg 
225                 230                 235                 240 


Tyr Pro Gly Gly Ser Trp Gly Asn Ile Asn Arg Tyr Pro Gly Gly Ser 
                245                 250                 255     


Trp Gly Asn Ile His Leu Tyr Pro Gly Ile Asn Asn Pro Phe Pro Pro 
            260                 265                 270         


Gly Val Leu Arg Pro Pro Gly Ser Ser Trp Asn Ile Pro Ala Gly Phe 
        275                 280                 285             


Pro Asn Pro Pro Ser Pro Arg Leu Gln Trp Gly 
    290                 295                 


<210>  2561
<211>  86
<212>  PRT
<213>  Homo Sapiens

<400>  2561

Cys Cys Met Lys Arg Lys Lys Lys Thr Ala Asn Pro Glu Asn Asn Leu 
1               5                   10                  15      


Ser Tyr Trp Asn Asn Thr Ile Thr Met Asp Tyr Phe Asn Arg His Ala 
            20                  25                  30          


Val Glu Leu Pro Arg Glu Ile Gln Ser Leu Glu Thr Ser Glu Asp Gln 
        35                  40                  45              


Leu Ser Glu Pro Arg Ser Pro Ala Asn Gly Asp Tyr Arg Asp Thr Gly 
    50                  55                  60                  


Met Val Leu Val Asn Pro Phe Cys Gln Glu Thr Leu Phe Val Gly Asn 
65                  70                  75                  80  


Asp Gln Val Ser Glu Ile 
                85      


<210>  2562
<211>  631
<212>  PRT
<213>  Homo Sapiens

<400>  2562

Asn Lys Glu Thr Ala Lys Lys Ile Lys Arg Pro Lys Phe Thr Val Pro 
1               5                   10                  15      


Gln Ile Asn Cys Asp Val Lys Ala Gly Lys Ile Ile Asp Pro Glu Phe 
            20                  25                  30          


Ile Val Lys Cys Pro Ala Gly Cys Gln Asp Pro Lys Tyr His Val Tyr 
        35                  40                  45              


Gly Thr Asp Val Tyr Ala Ser Tyr Ser Ser Val Cys Gly Ala Ala Val 
    50                  55                  60                  


His Ser Gly Val Leu Asp Asn Ser Gly Gly Lys Ile Leu Val Arg Lys 
65                  70                  75                  80  


Val Ala Gly Gln Ser Gly Tyr Lys Gly Ser Tyr Ser Asn Gly Val Gln 
                85                  90                  95      


Ser Leu Ser Leu Pro Arg Trp Arg Glu Ser Phe Ile Val Leu Glu Ser 
            100                 105                 110         


Lys Pro Lys Lys Gly Val Thr Tyr Pro Ser Ala Leu Thr Tyr Ser Ser 
        115                 120                 125             


Ser Lys Ser Pro Ala Ala Gln Ala Gly Glu Thr Thr Lys Ala Tyr Gln 
    130                 135                 140                 


Arg Pro Pro Ile Pro Gly Thr Thr Ala Gln Pro Val Thr Leu Met Gln 
145                 150                 155                 160 


Leu Leu Ala Val Thr Val Ala Val Ala Thr Pro Thr Thr Leu Pro Arg 
                165                 170                 175     


Pro Ser Pro Ser Ala Ala Ser Thr Thr Ser Ile Pro Arg Pro Gln Ser 
            180                 185                 190         


Val Gly His Arg Ser Gln Glu Met Asp Leu Trp Ser Thr Ala Thr Tyr 
        195                 200                 205             


Thr Ser Ser Gln Asn Arg Pro Arg Ala Asp Pro Gly Ile Gln Arg Gln 
    210                 215                 220                 


Asp Pro Ser Gly Ala Ala Phe Gln Lys Pro Val Gly Ala Asp Val Ser 
225                 230                 235                 240 


Leu Asp Cys Lys Ile Asp Leu Ser Phe Leu Ile Asp Gly Ser Thr Ser 
                245                 250                 255     


Ile Gly Lys Arg Arg Phe Arg Ile Gln Lys Gln Leu Leu Ala Asp Val 
            260                 265                 270         


Ala Gln Ala Leu Asp Ile Gly Pro Ala Gly Pro Leu Met Gly Val Val 
        275                 280                 285             


Gln Tyr Gly Asp Asn Pro Ala Thr His Phe Asn Leu Lys Thr His Thr 
    290                 295                 300                 


Asn Ser Arg Asp Leu Lys Thr Ala Ile Glu Lys Ile Thr Gln Arg Gly 
305                 310                 315                 320 


Gly Leu Ser Asn Val Gly Arg Ala Ile Ser Phe Val Thr Lys Asn Phe 
                325                 330                 335     


Phe Ser Lys Ala Asn Gly Asn Arg Ser Gly Ala Pro Asn Val Val Val 
            340                 345                 350         


Val Met Val Asp Gly Trp Pro Thr Asp Lys Val Glu Glu Ala Ser Arg 
        355                 360                 365             


Leu Ala Arg Glu Ser Gly Ile Asn Ile Phe Phe Ile Thr Ile Glu Gly 
    370                 375                 380                 


Ala Ala Glu Asn Glu Lys Gln Tyr Val Val Glu Pro Asn Phe Ala Asn 
385                 390                 395                 400 


Lys Ala Val Cys Arg Thr Asn Gly Phe Tyr Ser Leu His Val Gln Ser 
                405                 410                 415     


Trp Phe Gly Leu His Lys Thr Leu Gln Pro Leu Val Lys Arg Val Cys 
            420                 425                 430         


Asp Thr Asp Arg Leu Ala Cys Ser Lys Thr Cys Leu Asn Ser Ala Asp 
        435                 440                 445             


Ile Gly Phe Val Ile Asp Gly Ser Ser Ser Val Gly Thr Gly Asn Phe 
    450                 455                 460                 


Arg Thr Val Leu Gln Phe Val Thr Asn Leu Thr Lys Glu Phe Glu Ile 
465                 470                 475                 480 


Ser Asp Thr Asp Thr Arg Ile Gly Ala Val Gln Tyr Thr Tyr Glu Gln 
                485                 490                 495     


Arg Leu Glu Phe Gly Phe Asp Lys Tyr Ser Ser Arg Pro Asp Ile Ile 
            500                 505                 510         


Asn Ala Ile Lys Arg Val Gly Tyr Trp Ser Gly Gly Thr Ser Thr Gly 
        515                 520                 525             


Ala Ala Ile Asn Phe Ala Leu Glu Gln Leu Phe Lys Lys Ser Lys Pro 
    530                 535                 540                 


Asn Lys Arg Lys Leu Met Ile Leu Ile Thr Asp Gly Arg Ser Tyr Asp 
545                 550                 555                 560 


Asp Val Arg Ile Pro Ala Met Ala Ala His Leu Lys Gly Val Ile Thr 
                565                 570                 575     


Tyr Ala Ile Gly Val Ala Trp Ala Ala Gln Glu Glu Leu Glu Val Ile 
            580                 585                 590         


Ala Thr His Pro Ala Arg Asp His Ser Phe Phe Val Asp Glu Phe Asp 
        595                 600                 605             


Asn Leu Tyr Gln Tyr Val Pro Arg Ile Ile Gln Asn Ile Cys Thr Glu 
    610                 615                 620                 


Phe Asn Ser Gln Pro Arg Asn 
625                 630     


<210>  2563
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  2563

Ala Thr Val Arg Asn Glu Asp Lys Trp Lys Pro Leu Asn Asn Pro Arg 
1               5                   10                  15      


Asn Arg Asp Leu Phe Phe Arg Arg Leu Gln Ala Tyr Phe Lys Gly Arg 
            20                  25                  30          


Gly Leu Asp Leu Gly Thr Phe Pro Asn Pro Phe Pro Thr Asn Glu Asn 
        35                  40                  45              


Pro Arg Pro Leu Ser Phe Gln Ser Glu Leu Thr Ala Ser Ala Ser Ala 
    50                  55                  60                  


Asp Tyr Glu Glu Gln Lys Asn Ser Phe His Asn Tyr Leu Lys Gly 
65                  70                  75                  


<210>  2564
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  2564

Arg Pro Arg Gly Arg Arg Gly Ala Arg Val Thr Asp Lys Glu Pro Lys 
1               5                   10                  15      


Pro Leu Leu Phe Leu Pro Ala Ala Gly Ala Gly Arg Thr Pro Ser Gly 
            20                  25                  30          


Ser Arg Ser Ala Glu Ile Phe Pro Arg Asp Ser Asn Leu Lys Asp Lys 
        35                  40                  45              


Phe Ile Lys His Phe Thr Gly Pro Val Thr Phe Ser Pro Glu Cys Ser 
    50                  55                  60                  


Lys His Phe His Arg Leu Tyr Tyr Asn Thr Arg Glu Cys Ser Thr Pro 
65                  70                  75                  80  


Ala Tyr Tyr Lys Arg Cys Ala Arg Leu Leu Thr Arg Leu Ala Val Ser 
                85                  90                  95      


Pro Leu Cys Ser Gln Thr 
            100         


<210>  2565
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  2565

Arg Leu Arg Gly Pro Trp Gly Arg Ala Val Gly Glu Arg Thr Leu Pro 
1               5                   10                  15      


Gly Ala Gln Asp Arg Asp Asp Gly Glu Glu Ala Asp Gly Gly Gly Pro 
            20                  25                  30          


Ala Asp Gln Phe Ser Asp Gly Arg Glu Pro Leu Pro Gly Gly Cys Ser 
        35                  40                  45              


Leu Val Cys Lys Pro Ser Ala Leu Ala Gln Cys Leu Leu Arg Ala Leu 
    50                  55                  60                  


Arg Arg Ser Glu Ala Leu Glu Ala Gly Pro Arg Ser Trp Phe Ser Gly 
65                  70                  75                  80  


Pro His Leu Gln Thr Leu Cys His Phe Val Leu Pro Val Ala Pro Gly 
                85                  90                  95      


Pro Glu Leu Ala Arg Glu Tyr Leu Gln Leu Ala Asp Asp Gly Leu Val 
            100                 105                 110         


Ala Leu Asp Trp Val Val Gly Pro Cys Val Arg Gly Arg Arg Ile Thr 
        115                 120                 125             


Ser Ala Gly Gly Leu Pro Ala Val Leu Leu Val Ile Pro Asn Ala Trp 
    130                 135                 140                 


Gly Arg Leu Thr Arg Asn Val Leu Gly Leu Cys Leu Leu Ala Leu Glu 
145                 150                 155                 160 


Arg Gly Tyr Tyr Pro Val Ile Phe His Arg Arg Gly His His Gly Cys 
                165                 170                 175     


Pro Leu Val Ser Pro Arg Leu Gln Pro Phe Gly Asp Pro Ser Asp Leu 
            180                 185                 190         


Lys Glu Ala Val Thr Tyr Ile Arg Phe Arg His Pro Ala Ala Pro Leu 
        195                 200                 205             


Phe Ala Val Ser Glu Gly Ser Gly Ser Ala Leu Leu Leu Ser Tyr Leu 
    210                 215                 220                 


Gly Glu Cys Gly Ser Ser Ser Tyr Val Thr Gly Ala Ala Cys Ile Ser 
225                 230                 235                 240 


Pro Val Leu Arg Cys Arg Glu Trp Phe Glu Ala Gly Leu Pro Trp Pro 
                245                 250                 255     


Tyr Glu Arg Gly Phe Leu Leu Tyr Gln Lys Ile Ala Leu Ser Arg Tyr 
            260                 265                 270         


Ala Thr Ala Leu Glu Asp Thr Val Asp Thr Ser Arg Leu Phe Arg Ser 
        275                 280                 285             


Arg Ser Leu Arg Glu Phe Glu Glu Ala Leu Phe Cys His Thr Lys Ser 
    290                 295                 300                 


Phe Pro Ile Ser Trp Asp Ala Tyr Trp Asp Arg Asn Asp Pro Leu Arg 
305                 310                 315                 320 


Asp Val Asp Glu Ala Ala Val Pro Val Leu Cys Ile Cys Ser Ala Asp 
                325                 330                 335     


Asp Pro Val Cys Gly Pro Pro Asp His Thr Leu Thr Thr Glu Leu Phe 
            340                 345                 350         


His Ser Asn Pro Tyr Phe Phe Leu Leu Leu Ser Arg His Gly Gly His 
        355                 360                 365             


Cys Gly Phe Leu Arg Gln Glu Pro Leu Pro Ala Trp Ser His Glu Val 
    370                 375                 380                 


Ile Leu Glu Ser Phe Arg Ala Leu Thr Glu Phe Phe Arg Thr Glu Glu 
385                 390                 395                 400 


Arg Ile Lys Gly Leu Ser Arg His Arg Ala Ser Phe Leu Gly Gly Arg 
                405                 410                 415     


Arg Arg Gly Gly Ala Leu Gln Arg Arg Glu Val Ser Ser Ser Ser Asn 
            420                 425                 430         


Leu Glu Glu Ile Phe Asn Trp Lys Arg Ser Tyr Thr Arg 
        435                 440                 445 


<210>  2566
<211>  1290
<212>  PRT
<213>  Homo Sapiens

<400>  2566

Gly Pro Pro Val Pro Ala Ser Ser Ser Thr Lys Leu Leu Met Thr Ser 
1               5                   10                  15      


Tyr Ser Met Arg Ser Thr Val Val Ser Arg Tyr Ala His Thr Leu Val 
            20                  25                  30          


Thr Ser Val Leu Phe Asn Pro His Ala Glu Ala His Glu Ala Ile Phe 
        35                  40                  45              


Asp Leu Asp Leu Pro His Leu Ala Phe Ile Ser Asn Phe Thr Met Thr 
    50                  55                  60                  


Ile Asn Asn Lys Val Tyr Ile Ala Glu Val Lys Glu Lys His Gln Ala 
65                  70                  75                  80  


Lys Lys Ile Tyr Glu Glu Ala His Gln Gln Gly Lys Thr Ala Ala His 
                85                  90                  95      


Val Gly Ile Arg Asp Arg Glu Ser Glu Lys Phe Arg Ile Ser Thr Ser 
            100                 105                 110         


Leu Ala Ala Gly Thr Glu Val Thr Phe Ser Leu Ala Tyr Glu Glu Leu 
        115                 120                 125             


Leu Gln Arg His Gln Gly Gln Tyr Gln Leu Val Val Ser Leu Arg Pro 
    130                 135                 140                 


Gly Gln Leu Val Lys Arg Leu Ser Ile Glu Val Thr Val Ser Glu Arg 
145                 150                 155                 160 


Thr Gly Ile Ser Tyr Val His Ile Pro Pro Leu Arg Thr Gly Arg Leu 
                165                 170                 175     


Arg Thr Asn Ala His Ala Ser Glu Val Asp Ser Pro Pro Ser Thr Arg 
            180                 185                 190         


Ile Glu Arg Gly Glu Thr Cys Val Arg Ile Thr Tyr Cys Pro Thr Leu 
        195                 200                 205             


Gln Asp Gln Ser Ser Ile Ser Gly Ser Gly Ile Met Ala Asp Phe Leu 
    210                 215                 220                 


Val Gln Tyr Asp Val Val Met Glu Asp Ile Ile Gly Asp Val Gln Ile 
225                 230                 235                 240 


Tyr Asp Asp Tyr Phe Ile His Tyr Phe Ala Pro Arg Gly Leu Pro Pro 
                245                 250                 255     


Met Glu Lys Asn Val Val Phe Val Ile Asp Val Ser Ser Ser Met Phe 
            260                 265                 270         


Gly Thr Lys Met Glu Gln Thr Lys Thr Ala Met Asn Val Ile Leu Ser 
        275                 280                 285             


Asp Leu Gln Ala Asn Asp Tyr Phe Asn Ile Ile Ser Phe Ser Asp Thr 
    290                 295                 300                 


Val Asn Val Trp Lys Ala Gly Gly Ser Ile Gln Ala Thr Ile Gln Asn 
305                 310                 315                 320 


Val His Ser Ala Lys Asp Tyr Leu His Cys Met Glu Ala Asp Gly Trp 
                325                 330                 335     


Thr Asp Val Asn Ser Ala Leu Leu Ala Ala Ala Ser Val Leu Asn His 
            340                 345                 350         


Ser Asn Gln Glu Pro Gly Arg Gly Pro Ser Val Gly Arg Ile Pro Leu 
        355                 360                 365             


Ile Ile Phe Leu Thr Asp Gly Glu Pro Thr Ala Gly Val Thr Thr Pro 
    370                 375                 380                 


Ser Val Ile Leu Ser Asn Val Arg Gln Ala Leu Gly His Arg Val Ser 
385                 390                 395                 400 


Leu Phe Ser Leu Ala Phe Gly Asp Asp Ala Asp Phe Thr Leu Leu Arg 
                405                 410                 415     


Arg Leu Ser Leu Glu Asn Arg Gly Ile Ala Arg Arg Ile Tyr Glu Asp 
            420                 425                 430         


Thr Asp Ala Ala Leu Gln Leu Lys Gly Leu Tyr Glu Glu Ile Ser Met 
        435                 440                 445             


Pro Leu Leu Ala Asp Val Arg Leu Asn Tyr Leu Gly Gly Leu Val Gly 
    450                 455                 460                 


Ala Ser Pro Trp Ala Val Phe Pro Asn Tyr Phe Gly Gly Ser Glu Leu 
465                 470                 475                 480 


Val Val Ala Gly Gln Val Gln Pro Gly Lys Gln Glu Leu Gly Ile His 
                485                 490                 495     


Leu Ala Ala Arg Gly Pro Lys Asp Gln Leu Leu Val Ala His His Ser 
            500                 505                 510         


Glu Gly Ala Thr Asn Asn Ser Gln Lys Ala Phe Gly Cys Pro Gly Glu 
        515                 520                 525             


Pro Ala Pro Asn Val Ala His Phe Ile Arg Arg Leu Trp Ala Tyr Val 
    530                 535                 540                 


Thr Ile Gly Glu Leu Leu Asp Ala His Phe Gln Ala Arg Asp Thr Thr 
545                 550                 555                 560 


Thr Arg His Leu Leu Ala Ala Lys Val Leu Asn Leu Ser Leu Glu Tyr 
                565                 570                 575     


Asn Phe Val Thr Pro Leu Thr Ser Leu Val Met Val Gln Pro Lys Gln 
            580                 585                 590         


Ala Ser Glu Glu Thr Arg Arg Gln Thr Ser Thr Ser Ala Gly Pro Asp 
        595                 600                 605             


Thr Ile Met Pro Ser Ser Ser Ser Arg His Gly Leu Gly Val Ser Thr 
    610                 615                 620                 


Ala Gln Pro Ala Leu Val Pro Lys Val Ile Ser Pro Lys Ser Arg Pro 
625                 630                 635                 640 


Val Lys Pro Lys Phe Tyr Leu Ser Ser Thr Thr Thr Ala Ser Thr Lys 
                645                 650                 655     


Lys Met Leu Ser Ser Lys Glu Leu Glu Pro Leu Gly Glu Ser Pro His 
            660                 665                 670         


Thr Leu Ser Met Pro Thr Tyr Pro Lys Ala Lys Ile Pro Ala Gln Gln 
        675                 680                 685             


Asp Ser Gly Thr Leu Ala Gln Pro Thr Leu Arg Thr Lys Pro Thr Ile 
    690                 695                 700                 


Leu Val Pro Ser Asn Ser Gly Thr Leu Leu Pro Leu Lys Pro Gly Ser 
705                 710                 715                 720 


Leu Ser His Gln Asn Pro Asp Ile Leu Pro Thr Asn Ser Arg Thr Gln 
                725                 730                 735     


Val Pro Pro Val Lys Pro Gly Ile Pro Ala Ser Pro Lys Ala Asp Thr 
            740                 745                 750         


Val Lys Cys Val Thr Pro Leu His Ser Lys Pro Gly Ala Pro Ser His 
        755                 760                 765             


Pro Gln Leu Gly Ala Leu Thr Ser Gln Ala Pro Lys Gly Leu Pro Gln 
    770                 775                 780                 


Ser Arg Pro Gly Val Ser Thr Leu Gln Val Pro Lys Tyr Pro Leu His 
785                 790                 795                 800 


Thr Arg Pro Arg Val Pro Ala Pro Lys Thr Arg Asn Asn Met Pro His 
                805                 810                 815     


Leu Gly Pro Gly Ile Leu Leu Ser Lys Thr Pro Lys Ile Leu Leu Ser 
            820                 825                 830         


Leu Lys Pro Ser Ala Pro Pro His Gln Ile Ser Thr Ser Ile Ser Leu 
        835                 840                 845             


Ser Lys Pro Glu Thr Pro Asn Pro His Met Pro Gln Thr Pro Leu Pro 
    850                 855                 860                 


Pro Arg Pro Asp Arg Pro Arg Pro Pro Leu Pro Glu Ser Leu Ser Thr 
865                 870                 875                 880 


Phe Pro Asn Thr Ile Ser Ser Ser Thr Gly Pro Ser Ser Thr Thr Thr 
                885                 890                 895     


Thr Ser Val Leu Gly Glu Pro Leu Pro Met Pro Phe Thr Pro Thr Leu 
            900                 905                 910         


Pro Pro Gly Arg Phe Trp His Gln Tyr Asp Leu Leu Pro Gly Pro Gln 
        915                 920                 925             


Arg Thr Arg Gln Val Leu Gly Pro Ser Arg Pro Gly Val Pro Thr Met 
    930                 935                 940                 


Ser Leu Leu Asn Ser Ser Arg Pro Thr Pro Glu Gly Ser Pro Pro Asn 
945                 950                 955                 960 


Leu Pro Ile Leu Leu Pro Ser Ser Ile Leu Pro Glu Ala Ile Ser Leu 
                965                 970                 975     


Leu Leu Leu Pro Glu Glu Leu Glu Leu Leu Ser Glu Ser Met Val Glu 
            980                 985                 990         


Ser Lys Phe Val Glu Ser Leu Asn  Pro Pro Ala Phe Tyr  Thr Phe Leu 
        995                 1000                 1005             


Thr Pro  Asp Glu Asp Gly Ser  Pro Asn Trp Asp Gly  Asn Ser Glu 
    1010                 1015                 1020             


Glu Ile  Leu Gly Gly Ala Gly  Gly Ser Met Glu Ser  Gln Gly Ser 
    1025                 1030                 1035             


Ser Val  Gly Leu Ala Lys Gly  Thr Leu Pro Ser Ile  Phe Thr Phe 
    1040                 1045                 1050             


Ser Ser  Ser Val Asp Gly Asp  Pro His Phe Val Ile  Gln Ile Pro 
    1055                 1060                 1065             


His Ser  Glu Glu Lys Ile Cys  Phe Thr Leu Asn Gly  His Pro Gly 
    1070                 1075                 1080             


Asp Leu  Leu Gln Leu Ile Glu  Asp Pro Lys Ala Gly  Leu His Val 
    1085                 1090                 1095             


Ser Gly  Lys Leu Leu Gly Ala  Pro Pro Arg Pro Gly  His Lys Asp 
    1100                 1105                 1110             


Gln Thr  Arg Thr Tyr Phe Gln  Ile Ile Thr Val Thr  Thr Asp Lys 
    1115                 1120                 1125             


Pro Arg  Ala Tyr Thr Ile Thr  Ile Ser Arg Ser Ser  Ile Ser Leu 
    1130                 1135                 1140             


Arg Gly  Glu Gly Thr Leu Arg  Leu Ser Trp Asp Gln  Pro Ala Leu 
    1145                 1150                 1155             


Leu Lys  Arg Pro Gln Leu Glu  Leu Tyr Val Ala Ala  Ala Ala Arg 
    1160                 1165                 1170             


Leu Thr  Leu Arg Leu Gly Pro  Tyr Leu Glu Phe Leu  Val Leu Arg 
    1175                 1180                 1185             


His Arg  Tyr Arg His Pro Ser  Thr Leu Gln Leu Pro  His Leu Gly 
    1190                 1195                 1200             


Phe Tyr  Val Ala Asn Gly Ser  Gly Leu Ser Pro Ser  Ala Arg Gly 
    1205                 1210                 1215             


Leu Ile  Gly Gln Phe Gln His  Ala Asp Ile Arg Leu  Val Thr Gly 
    1220                 1225                 1230             


Pro Met  Gly Pro Cys Leu Arg  Arg His His Gly Pro  Asp Val Pro 
    1235                 1240                 1245             


Val Ile  Leu Gly Lys Arg Leu  Leu Lys Asp Ser Pro  Arg Leu Leu 
    1250                 1255                 1260             


Pro Arg  Trp Ala Ser Cys Trp  Leu Val Lys Arg Ser  His Val Glu 
    1265                 1270                 1275             


Leu Leu  Leu Gly His Pro Tyr  Leu Ser Tyr Val Leu  
    1280                 1285                 1290 


<210>  2567
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  2567

Arg Ala Arg Pro Asp Met Phe Cys Leu Phe His Gly Lys Arg Tyr Ser 
1               5                   10                  15      


Pro Gly Glu Ser Trp His Pro Tyr Leu Glu Pro Gln Gly Leu Met Tyr 
            20                  25                  30          


Cys Leu Arg Cys Thr Cys Ser Glu Gly Ala His Val Ser Cys Tyr Arg 
        35                  40                  45              


Leu His Cys Pro Pro Val His Cys Pro Gln Pro Val Thr Glu Pro Gln 
    50                  55                  60                  


Gln Cys Cys Pro Lys Cys Val Glu Pro His Thr Pro Ser Gly Leu Arg 
65                  70                  75                  80  


Ala Pro Pro Lys Ser Cys Gln His Asn Gly Thr Met Tyr Gln His Gly 
                85                  90                  95      


Glu Ile Phe Ser Ala His Glu Leu Phe Pro Ser Arg Leu Pro Asn Gln 
            100                 105                 110         


Cys Val Leu Cys Ser Cys Thr Glu Gly Gln Ile Tyr Cys Gly Leu Thr 
        115                 120                 125             


Thr Cys Pro Glu Pro Gly Cys Pro Ala Pro Leu Pro Leu Pro Asp Ser 
    130                 135                 140                 


Cys Cys Gln Ala Cys Lys Asp Glu Ala Ser Glu Gln Ser Asp Glu Glu 
145                 150                 155                 160 


Asp Ser Val Gln Ser Leu His Gly Val Arg His Pro Gln Asp Pro Cys 
                165                 170                 175     


Ser Ser Asp Ala Gly Arg Lys Arg Gly Pro Gly Thr Pro Ala Pro Thr 
            180                 185                 190         


Gly Leu Ser Ala Pro Leu Ser Phe Ile Pro Arg His Phe Arg Pro Lys 
        195                 200                 205             


Gly Ala Gly Ser Thr Thr Val Lys Ile Val Leu Lys Glu Lys His Lys 
    210                 215                 220                 


Lys Ala Cys Val His Gly Gly Lys Thr Tyr Ser His Gly Glu Val Trp 
225                 230                 235                 240 


His Pro Ala Phe Arg Ala Phe Gly Pro Leu Pro Cys Ile Leu Cys Thr 
                245                 250                 255     


Cys Glu Asp Gly Arg Gln Asp Cys Gln Arg Val Thr Cys Pro Thr Glu 
            260                 265                 270         


Tyr Pro Cys Arg His Pro Glu Lys Val Ala Gly Lys Cys Cys Lys Ile 
        275                 280                 285             


Cys Pro Glu Asp Lys Ala Asp Pro Gly His Ser Glu Ile Ser Ser Thr 
    290                 295                 300                 


Arg Cys Pro Lys Ala Pro Gly Arg Val Leu Val His Thr Ser Val Ser 
305                 310                 315                 320 


Pro Ser Pro Asp Asn Leu Arg Arg Phe Ala Leu Glu His Glu Ala Ser 
                325                 330                 335     


Asp Leu Val Glu Ile Tyr Leu Trp Lys Leu Val Lys Asp Glu Glu Thr 
            340                 345                 350         


Glu Ala Gln Arg Gly Glu Val Pro Gly Pro Arg Pro His Ser Gln Asn 
        355                 360                 365             


Leu Pro Leu Asp Ser Asp Gln Glu Ser Gln Glu Ala Arg Leu Pro Glu 
    370                 375                 380                 


Arg Gly Thr Ala Leu Pro Thr Ala Arg Trp Pro Pro Arg Arg Ser Leu 
385                 390                 395                 400 


Glu Arg Leu Pro Ser Pro Asp Pro Gly Ala Glu Gly His Gly Gln Ser 
                405                 410                 415     


Arg Gln Ser Asp Gln Asp Ile 
            420             


<210>  2568
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2568

Phe Lys Asn Asp Ala Thr Glu Ile Leu Tyr Ser His Val Val Lys Pro 
1               5                   10                  15      


Val Pro Ala His Pro Ser Ser Asn Ser Thr Leu Asn Gln Ala Arg Asn 
            20                  25                  30          


Gly Gly Arg His Phe Ser Asn Thr Gly Leu Asp Arg Asn Thr Arg Val 
        35                  40                  45              


Gln Val Gly Cys Arg Glu Leu Arg Ser Thr Lys Tyr Ile Ser Asp Gly 
    50                  55                  60                  


Gln Cys Thr Ser Ile Ser Pro Leu Lys Glu Leu Val Cys Ala Gly Glu 
65                  70                  75                  80  


Cys Leu Pro Leu Pro Val Leu Pro Asn Trp Ile Gly Gly Gly Tyr Gly 
                85                  90                  95      


Thr Lys Tyr Trp Ser Arg Arg Ser Ser Gln Glu Trp Arg Cys Val Asn 
            100                 105                 110         


Asp Lys Thr Arg Thr Gln Arg Ile Gln Leu Gln Cys Gln Asp Gly Ser 
        115                 120                 125             


Thr Arg Thr Tyr Lys Ile Thr Val Val Thr Ala Cys Lys Cys Lys Arg 
    130                 135                 140                 


Tyr Thr Arg Gln His Asn Glu Ser Ser His Asn Phe Glu Ser Met Ser 
145                 150                 155                 160 


Pro Ala Lys Pro Val Gln His His Arg Glu Arg Lys Arg Ala Ser Lys 
                165                 170                 175     


Ser Ser Lys His Ser Met Ser 
            180             


<210>  2569
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  2569

Leu Val Cys Pro Ala Val Ala Ser Glu Ile Thr Val Phe Leu Phe Leu 
1               5                   10                  15      


Ser Asp Ala Ala Val Asn Leu Gln Val Ala Lys Leu Asn Pro Pro Pro 
            20                  25                  30          


Glu Ala Leu Ala Ala Lys Leu Glu Val Lys His Cys Thr Asp Gln Ile 
        35                  40                  45              


Ser Phe Lys Lys Arg Leu Ser Leu Lys Lys Ser Trp Trp Lys 
    50                  55                  60          


<210>  2570
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  2570

Asp Asn Lys Arg Pro Cys Leu Glu Phe Ser Gln Leu Ser Val Lys Asp 
1               5                   10                  15      


Ser Phe Arg Asp Leu Phe Ile Pro Arg Ile Glu Thr Ile Leu Met Met 
            20                  25                  30          


Tyr Thr Arg Asn Asn Leu Asn Cys Ala Glu Pro Leu Phe Glu Gln Asn 
        35                  40                  45              


Asn Ser Leu Asn Val Asn Phe Asn Thr Gln Lys Lys Thr Val Trp Leu 
    50                  55                  60                  


Ile His Gly Tyr Arg Pro Val Gly Ser Ile Pro Leu Trp Leu Gln Asn 
65                  70                  75                  80  


Phe Val Arg Ile Leu Leu Asn Glu Glu Asp Met Asn Val Ile Val Val 
                85                  90                  95      


Asp Trp Ser Arg Gly Ala Thr Thr Phe Ile Tyr Asn Arg Ala Val Lys 
            100                 105                 110         


Asn Thr Arg Lys Val Ala Val Ser Leu Ser Val His Ile Lys Asn Leu 
        115                 120                 125             


Leu Lys His Gly Ala Ser Leu Asp Asn Phe His Phe Ile Gly Val Ser 
    130                 135                 140                 


Leu Gly Ala His Ile Ser Gly Phe Val Gly Lys Ile Phe His Gly Gln 
145                 150                 155                 160 


Leu Gly Arg Ile Thr Gly Leu Asp Pro Ala Gly Pro Arg Phe Ser Arg 
                165                 170                 175     


Lys Pro Pro Tyr Ser Arg Leu Asp Tyr Thr Asp Ala Lys Phe Val Asp 
            180                 185                 190         


Val Ile His Ser Asp Ser Asn Gly Leu Gly Ile Gln Glu Pro Leu Gly 
        195                 200                 205             


His Ile Asp Phe Tyr Pro Asn Gly Gly Asn Lys Gln Pro Gly Cys Pro 
    210                 215                 220                 


Lys Ser Ile Phe Ser Gly Ile Gln Phe Ile Lys Cys Asn His Gln Arg 
225                 230                 235                 240 


Ala Val His Leu Phe Met Ala Ser Leu Glu Thr Asn Cys Asn Phe Ile 
                245                 250                 255     


Ser Phe Pro Cys Arg Ser Tyr Lys Asp Tyr Lys Thr Ser Leu Cys Val 
            260                 265                 270         


Asp Cys Asp Cys Phe Lys Glu Lys Ser Cys Pro Arg Leu Gly Tyr Gln 
        275                 280                 285             


Ala Lys Leu Phe Lys Gly Val Leu Lys Glu Arg Met Glu Gly Arg Pro 
    290                 295                 300                 


Leu Arg Thr Thr Val Phe Leu Asp Thr Ser Gly Thr Tyr Pro Phe Cys 
305                 310                 315                 320 


Thr Tyr Tyr Phe Val Leu Ser Ile Ile Val Pro Asp Lys Thr Met Met 
                325                 330                 335     


Asp Gly Ser Phe Ser Phe Lys Leu Leu Asn Gln Leu Gly Met Ile Glu 
            340                 345                 350         


Glu Pro Arg Leu Tyr Glu Lys Asn Lys Pro Phe Tyr Lys Leu Gln Glu 
        355                 360                 365             


Val Lys Ile Leu Ala Gln Phe Tyr Asn Asp Phe Val Asn Ile Ser Ser 
    370                 375                 380                 


Ile Gly Leu Thr Tyr Phe Gln Ser Ser Asn Leu Gln Cys Ser Thr Cys 
385                 390                 395                 400 


Thr Tyr Lys Ile Gln Arg Leu Met Leu Lys Ser Leu Thr Tyr Pro Glu 
                405                 410                 415     


Arg Pro Pro Leu Cys Arg Tyr Asn Ile Val Leu Lys Asp Arg Glu Glu 
            420                 425                 430         


Val Phe Leu Asn Pro Asn Thr Cys Thr Pro Lys Asn Thr 
        435                 440                 445 


<210>  2571
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  2571

Trp Val Gly Gly Ser Val Pro Asn Leu Gly Pro Ala Glu Gln Glu Gln 
1               5                   10                  15      


Asn His Tyr Leu Ala Gln Leu Phe Gly Leu Tyr Gly Glu Asn Gly Thr 
            20                  25                  30          


Leu Thr Ala Gly Gly Leu Ala Arg Leu Leu His Ser Leu Gly Leu Gly 
        35                  40                  45              


Arg Val Gln Gly Leu Arg Leu Gly Gln His Gly Pro Leu Thr Gly Arg 
    50                  55                  60                  


Ala Ala Ser Pro Ala Ala Asp Asn Ser Thr His Arg Pro Gln Asn Pro 
65                  70                  75                  80  


Glu Leu Ser Val Asp Val Trp Ala Gly Met Pro Leu Gly Pro Ser Gly 
                85                  90                  95      


Trp Gly Asp Leu Glu Glu Ser Lys Ala Pro His Leu Pro Arg Gly Pro 
            100                 105                 110         


Ala Pro Ser Gly Leu Asp Leu Leu His Arg Leu Leu Leu Leu Asp His 
        115                 120                 125             


Ser Leu Ala Asp His Leu Asn Glu Asp Cys Leu Asn Gly Ser Gln Leu 
    130                 135                 140                 


Leu Val Asn Phe Gly Leu Ser Pro Ala Ala Pro Leu Thr Pro Arg Gln 
145                 150                 155                 160 


Phe Ala Leu Leu Cys Pro Ala Leu Leu Tyr Gln Ile Asp Ser Arg Val 
                165                 170                 175     


Cys Ile Gly Ala Pro Ala Pro Ala Pro Pro Gly Asp Leu Leu Ser Ala 
            180                 185                 190         


<210>  2572
<211>  379
<212>  PRT
<213>  Homo Sapiens

<400>  2572

His Phe Leu Val Phe Asp Gln Lys Lys Glu Tyr Tyr His Gly Ser Phe 
1               5                   10                  15      


Lys Ile Leu Asp Pro Gln Ile Asn Asn Asn Phe Gly Gln Ser Asn Thr 
            20                  25                  30          


Tyr Gln Leu Lys Asp Leu Arg Glu Thr Thr Glu Asn Leu Val Asp Glu 
        35                  40                  45              


Ile Phe Ile Asp Ser Ala Trp Lys Lys Asn Tyr Ile Lys Asn Gln Val 
    50                  55                  60                  


Val Arg Leu Thr Pro Glu Glu Asp Gly Val Lys Val Asp Val Ile Met 
65                  70                  75                  80  


Val Phe Gln Phe Pro Ser Thr Glu Gln Arg Ala Val Arg Glu Lys Lys 
                85                  90                  95      


Ile Gln Ser Ile Leu Asn Gln Lys Ile Arg Asn Leu Arg Ala Leu Pro 
            100                 105                 110         


Ile Asn Ala Ser Ser Val Gln Val Asn Ala Met Ser Ser Ser Thr Gly 
        115                 120                 125             


Glu Leu Thr Val Gln Ala Ser Cys Gly Lys Arg Val Val Pro Leu Asn 
    130                 135                 140                 


Val Asn Arg Ile Ala Ser Gly Val Ile Ala Pro Lys Ala Ala Trp Pro 
145                 150                 155                 160 


Trp Gln Ala Ser Leu Gln Tyr Asp Asn Ile His Gln Cys Gly Ala Thr 
                165                 170                 175     


Leu Ile Ser Asn Thr Trp Leu Val Thr Ala Ala His Cys Phe Gln Lys 
            180                 185                 190         


Tyr Lys Asn Pro His Gln Trp Thr Val Ser Phe Gly Thr Lys Ile Asn 
        195                 200                 205             


Pro Pro Leu Met Lys Arg Asn Val Arg Arg Phe Ile Ile His Glu Lys 
    210                 215                 220                 


Tyr Arg Ser Ala Ala Arg Glu Tyr Asp Ile Ala Val Val Gln Val Ser 
225                 230                 235                 240 


Ser Arg Val Thr Phe Ser Asp Asp Ile Arg Arg Ile Cys Leu Pro Glu 
                245                 250                 255     


Ala Ser Ala Ser Phe Gln Pro Asn Leu Thr Val His Ile Thr Gly Phe 
            260                 265                 270         


Gly Ala Leu Tyr Tyr Gly Gly Glu Ser Gln Asn Asp Leu Arg Glu Ala 
        275                 280                 285             


Arg Val Lys Ile Ile Ser Asp Asp Val Cys Lys Gln Pro Gln Val Tyr 
    290                 295                 300                 


Gly Asn Asp Ile Lys Pro Gly Met Phe Cys Ala Gly Tyr Met Glu Gly 
305                 310                 315                 320 


Ile Tyr Asp Ala Cys Arg Gly Asp Ser Gly Gly Pro Leu Val Thr Arg 
                325                 330                 335     


Asp Leu Lys Asp Thr Trp Tyr Leu Ile Gly Ile Val Ser Trp Gly Asp 
            340                 345                 350         


Asn Cys Gly Gln Lys Asp Lys Pro Gly Val Tyr Thr Gln Val Thr Tyr 
        355                 360                 365             


Tyr Arg Asn Trp Ile Ala Ser Lys Thr Gly Ile 
    370                 375                 


<210>  2573
<211>  412
<212>  PRT
<213>  Homo Sapiens

<400>  2573

Ala Pro Ser Ala Ala Pro Glu Gln Val His Leu Ser Tyr Pro Gly Glu 
1               5                   10                  15      


Pro Gly Ser Met Thr Val Thr Trp Thr Thr Trp Val Pro Thr Arg Ser 
            20                  25                  30          


Glu Val Gln Phe Gly Leu Gln Pro Ser Gly Pro Leu Pro Leu Arg Ala 
        35                  40                  45              


Gln Gly Thr Phe Val Pro Phe Val Asp Gly Gly Ile Leu Arg Arg Lys 
    50                  55                  60                  


Leu Tyr Ile His Arg Val Thr Leu Arg Lys Leu Leu Pro Gly Val Gln 
65                  70                  75                  80  


Tyr Val Tyr Arg Cys Gly Ser Ala Gln Gly Trp Ser Arg Arg Phe Arg 
                85                  90                  95      


Phe Arg Ala Leu Lys Asn Gly Ala His Trp Ser Pro Arg Leu Ala Val 
            100                 105                 110         


Phe Gly Asp Leu Gly Ala Asp Asn Pro Lys Ala Val Pro Arg Leu Arg 
        115                 120                 125             


Arg Asp Thr Gln Gln Gly Met Tyr Asp Ala Val Leu His Val Gly Asp 
    130                 135                 140                 


Phe Ala Tyr Asn Leu Asp Gln Asp Asn Ala Arg Val Gly Asp Arg Phe 
145                 150                 155                 160 


Met Arg Leu Ile Glu Pro Val Ala Ala Ser Leu Pro Tyr Met Thr Cys 
                165                 170                 175     


Pro Gly Asn His Glu Glu Arg Tyr Asn Phe Ser Asn Tyr Lys Ala Arg 
            180                 185                 190         


Phe Ser Met Pro Gly Asp Asn Glu Gly Leu Trp Tyr Ser Trp Asp Leu 
        195                 200                 205             


Gly Pro Ala His Ile Ile Ser Phe Ser Thr Glu Val Tyr Phe Phe Leu 
    210                 215                 220                 


His Tyr Gly Arg His Leu Val Gln Arg Gln Phe Arg Trp Leu Glu Ser 
225                 230                 235                 240 


Asp Leu Gln Lys Ala Asn Lys Asn Arg Ala Ala Arg Pro Trp Ile Ile 
                245                 250                 255     


Thr Met Gly His Arg Pro Met Tyr Cys Ser Asn Ala Asp Leu Asp Asp 
            260                 265                 270         


Cys Thr Arg His Glu Ser Lys Val Arg Lys Gly Leu Gln Gly Lys Leu 
        275                 280                 285             


Tyr Gly Leu Glu Asp Leu Phe Tyr Lys Tyr Gly Val Asp Leu Gln Leu 
    290                 295                 300                 


Trp Ala His Glu His Ser Tyr Glu Arg Leu Trp Pro Ile Tyr Asn Tyr 
305                 310                 315                 320 


Gln Val Phe Asn Gly Ser Arg Glu Met Pro Tyr Thr Asn Pro Arg Gly 
                325                 330                 335     


Pro Val His Ile Ile Thr Gly Ser Ala Gly Cys Glu Glu Arg Leu Thr 
            340                 345                 350         


Pro Phe Ala Val Phe Pro Arg Pro Trp Ser Ala Val Arg Val Lys Glu 
        355                 360                 365             


Tyr Gly Tyr Thr Arg Leu His Ile Leu Asn Gly Thr His Ile His Ile 
    370                 375                 380                 


Gln Gln Val Ser Asp Asp Gln Asp Gly Lys Ile Val Asp Asp Val Trp 
385                 390                 395                 400 


Val Val Arg Pro Leu Phe Gly Arg Arg Met Tyr Leu 
                405                 410         


<210>  2574
<211>  88
<212>  PRT
<213>  Homo Sapiens

<400>  2574

Ser Asp Tyr Trp Leu Leu Ala Thr Glu Val Gly Arg Cys Ser Gly Glu 
1               5                   10                  15      


Lys Asn Ile Glu Asn Val Thr Phe His His Glu Gly Phe Phe Trp Arg 
            20                  25                  30          


Cys Trp Phe Asn Gly Ile Val Glu Glu Asn Asp Ser Asn Ile Trp Lys 
        35                  40                  45              


Phe Trp Tyr Thr Asn Gln Pro Pro Ser Lys Asn Cys Thr His Ala Tyr 
    50                  55                  60                  


Leu Ser Pro Tyr Pro Phe Met Arg Gly Glu His Asn Ser Thr Ser Tyr 
65                  70                  75                  80  


Asp Ser Ala Val Ile Tyr Arg Gly 
                85              


<210>  2575
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  2575

Met Tyr Ala Lys Cys Glu Asn Glu Pro Phe Ala Gly Val Ser Glu Ser 
1               5                   10                  15      


Tyr Asn Gly Thr Gly Glu Leu Gly Asn Leu Ile Ala Pro Cys Asn Ala 
            20                  25                  30          


Asn Cys Asn Cys Ser Arg Ser Tyr Tyr Tyr Pro Val Cys Gly Asp Gly 
        35                  40                  45              


Val Gln Tyr Phe Ser Pro Cys Phe Ala Gly Cys Ser Asn Pro Val Ala 
    50                  55                  60                  


His Arg Lys Pro Lys Val Tyr Tyr Asn Cys Ser Cys Ile Glu Arg Lys 
65                  70                  75                  80  


Thr Glu Ile Thr Ser Thr Ala Glu Thr Phe Gly Phe Glu Ala Lys Ala 
                85                  90                  95      


Gly Lys Cys Glu Thr His Cys Ala Lys Leu Pro Ile Phe 
            100                 105                 


<210>  2576
<211>  694
<212>  PRT
<213>  Homo Sapiens

<400>  2576

Leu His Leu Ile Leu Leu Pro Ala Thr Gly Asn Val Ala Glu Asn Ser 
1               5                   10                  15      


Pro Pro Gly Thr Ser Val His Lys Phe Ser Val Lys Leu Ser Ala Ser 
            20                  25                  30          


Leu Ser Pro Val Ile Pro Gly Phe Pro Gln Ile Val Asn Ser Asn Pro 
        35                  40                  45              


Leu Thr Glu Ala Phe Arg Val Asn Trp Leu Ser Gly Thr Tyr Phe Glu 
    50                  55                  60                  


Val Val Thr Thr Gly Met Glu Gln Leu Asp Phe Glu Thr Gly Pro Asn 
65                  70                  75                  80  


Ile Phe Asp Leu Gln Ile Tyr Val Lys Asp Glu Val Gly Val Thr Asp 
                85                  90                  95      


Leu Gln Val Leu Thr Val Gln Val Thr Asp Val Asn Glu Pro Pro Gln 
            100                 105                 110         


Phe Gln Gly Asn Leu Ala Glu Gly Leu His Leu Tyr Ile Val Glu Arg 
        115                 120                 125             


Ala Asn Pro Gly Phe Ile Tyr Gln Val Glu Ala Phe Asp Pro Glu Asp 
    130                 135                 140                 


Thr Ser Arg Asn Ile Pro Leu Ser Tyr Phe Leu Ile Ser Pro Pro Lys 
145                 150                 155                 160 


Ser Phe Arg Met Ser Ala Asn Gly Thr Leu Phe Ser Thr Thr Glu Leu 
                165                 170                 175     


Asp Phe Glu Ala Gly His Arg Ser Phe His Leu Ile Val Glu Val Arg 
            180                 185                 190         


Asp Ser Gly Gly Leu Lys Ala Ser Thr Glu Leu Gln Val Asn Ile Val 
        195                 200                 205             


Asn Leu Asn Asp Glu Val Pro Arg Phe Thr Ser Pro Thr Arg Val Tyr 
    210                 215                 220                 


Thr Val Leu Glu Glu Leu Ser Pro Gly Thr Ile Val Ala Asn Ile Thr 
225                 230                 235                 240 


Ala Glu Asp Pro Asp Asp Glu Gly Phe Pro Ser His Leu Leu Tyr Ser 
                245                 250                 255     


Ile Thr Thr Val Ser Lys Tyr Phe Met Ile Asn Gln Leu Thr Gly Thr 
            260                 265                 270         


Ile Gln Val Ala Gln Arg Ile Asp Arg Asp Ala Gly Glu Leu Arg Gln 
        275                 280                 285             


Asn Pro Thr Ile Ser Leu Glu Val Leu Val Lys Asp Arg Pro Tyr Gly 
    290                 295                 300                 


Gly Gln Glu Asn Arg Ile Gln Ile Thr Phe Ile Val Glu Asp Val Asn 
305                 310                 315                 320 


Asp Asn Pro Ala Thr Cys Gln Lys Phe Thr Phe Ser Ile Met Val Pro 
                325                 330                 335     


Glu Arg Thr Ala Lys Gly Thr Leu Leu Leu Asp Leu Asn Lys Phe Cys 
            340                 345                 350         


Phe Asp Asp Asp Ser Glu Ala Pro Asn Asn Arg Phe Asn Phe Thr Met 
        355                 360                 365             


Pro Ser Gly Val Gly Ser Gly Ser Arg Phe Leu Gln Asp Pro Ala Gly 
    370                 375                 380                 


Ser Gly Lys Ile Val Leu Ile Gly Asp Leu Asp Tyr Glu Asn Pro Ser 
385                 390                 395                 400 


Asn Leu Ala Ala Gly Asn Lys Tyr Thr Val Ile Ile Gln Val Gln Asp 
                405                 410                 415     


Val Ala Pro Pro Tyr Tyr Lys Asn Asn Val Tyr Val Tyr Ile Leu Thr 
            420                 425                 430         


Ser Pro Glu Asn Glu Phe Pro Leu Ile Phe Asp Arg Pro Ser Tyr Val 
        435                 440                 445             


Phe Asp Val Ser Glu Arg Arg Pro Ala Arg Thr Arg Val Gly Gln Val 
    450                 455                 460                 


Arg Ala Thr Asp Lys Asp Leu Pro Gln Ser Ser Leu Leu Tyr Ser Ile 
465                 470                 475                 480 


Ser Thr Gly Gly Ala Ser Leu Gln Tyr Pro Asn Val Phe Trp Ile Asn 
                485                 490                 495     


Pro Lys Thr Gly Glu Leu Gln Leu Val Thr Lys Val Asp Cys Glu Thr 
            500                 505                 510         


Thr Pro Ile Tyr Ile Leu Arg Ile Gln Ala Thr Asn Asn Glu Asp Thr 
        515                 520                 525             


Ser Ser Val Thr Val Thr Val Asn Ile Leu Glu Glu Asn Asp Glu Lys 
    530                 535                 540                 


Pro Ile Cys Thr Pro Asn Ser Tyr Phe Leu Ala Leu Pro Val Asp Leu 
545                 550                 555                 560 


Lys Val Gly Thr Asn Ile Gln Asn Phe Lys Leu Thr Cys Thr Asp Leu 
                565                 570                 575     


Asp Ser Ser Pro Arg Ser Phe Arg Tyr Ser Ile Gly Pro Gly Asn Val 
            580                 585                 590         


Asn Asn His Phe Thr Phe Ser Pro Asn Ala Gly Ser Asn Val Thr Arg 
        595                 600                 605             


Leu Leu Leu Thr Ser Arg Phe Asp Tyr Ala Gly Gly Phe Asp Lys Ile 
    610                 615                 620                 


Trp Asp Tyr Lys Leu Leu Val Tyr Val Thr Asp Asp Asn Leu Met Ser 
625                 630                 635                 640 


Asp Arg Lys Lys Ala Glu Ala Leu Val Glu Thr Gly Thr Val Thr Leu 
                645                 650                 655     


Ser Ile Lys Val Ile Pro His Pro Thr Thr Ile Ile Thr Thr Thr Pro 
            660                 665                 670         


Arg Pro Arg Val Thr Tyr Gln Val Leu Arg Lys Asn Val Tyr Ser Pro 
        675                 680                 685             


Ser Ala Trp Tyr Val Pro 
    690                 


<210>  2577
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  2577

Lys Gly Lys Phe Val Gly Tyr Pro Gly Lys Tyr Thr Tyr Leu Phe Asn 
1               5                   10                  15      


Glu Trp Arg Ser Glu Glu Cys Asp Pro Gly Gly Cys Leu Ile Glu Leu 
            20                  25                  30          


Thr Thr Gln Leu Thr Ile Ile Met Thr Gly Lys Gln Ile Phe Gly Asn 
        35                  40                  45              


Ile Lys Glu Ala Ile Tyr Pro Leu Ala Leu Asn Trp Trp Arg Arg Arg 
    50                  55                  60                  


Lys Ala Arg Thr Asn Ser Glu Lys Leu Tyr Ser Arg Trp Glu Gln Asp 
65                  70                  75                  80  


His Asp Leu Glu Ser Phe Gly Pro Leu Gly Leu Phe Tyr Glu Tyr Leu 
                85                  90                  95      


Glu Thr Val Thr Gln 
            100     


<210>  2578
<211>  733
<212>  PRT
<213>  Homo Sapiens

<400>  2578

Ala Val Ser Asp Gln His Ala Thr Ser Pro Phe Asp Trp Leu Leu Ser 
1               5                   10                  15      


Asp Lys Gly Pro Phe His Arg Ser Gln Glu Tyr Thr Asp Phe Val Asp 
            20                  25                  30          


Arg Ser Arg Gln Gly Phe Ser Thr Arg Tyr Lys Ile Tyr Arg Glu Phe 
        35                  40                  45              


Gly Arg Trp Lys Val Asn Asn Leu Ala Val Glu Arg Arg Asn Phe Leu 
    50                  55                  60                  


Gly Ser Pro Leu Pro Leu Ala Pro Glu Phe Phe Arg Asn Ile Arg Leu 
65                  70                  75                  80  


Leu Gly Arg Arg Pro Thr Leu Gln Gln Ile Thr Glu Asn Leu Ile Lys 
                85                  90                  95      


Lys Tyr Gly Thr His Phe Leu Leu Ser Ala Thr Leu Gly Gly Glu Glu 
            100                 105                 110         


Ser Leu Thr Ile Phe Val Asp Lys Arg Lys Leu Ser Lys Arg Ala Glu 
        115                 120                 125             


Gly Ser Asp Ser Thr Thr Asn Ser Ser Ser Val Thr Leu Glu Thr Leu 
    130                 135                 140                 


His Gln Leu Ala Ala Ser Tyr Phe Ile Asp Arg Asp Ser Thr Leu Arg 
145                 150                 155                 160 


Arg Leu His His Ile Gln Ile Ala Ser Thr Ala Ile Lys Val Thr Glu 
                165                 170                 175     


Thr Arg Thr Gly Pro Leu Gly Cys Ser Asn Tyr Asp Asn Leu Asp Ser 
            180                 185                 190         


Val Ser Ser Val Leu Val Gln Ser Pro Glu Asn Lys Ile Gln Leu Gln 
        195                 200                 205             


Gly Leu Gln Val Leu Leu Pro Asp Tyr Leu Gln Glu Arg Phe Val Gln 
    210                 215                 220                 


Ala Ala Leu Ser Tyr Ile Ala Cys Asn Ser Glu Gly Glu Phe Ile Cys 
225                 230                 235                 240 


Lys Glu Asn Asp Cys Trp Cys His Cys Gly Pro Lys Phe Pro Glu Cys 
                245                 250                 255     


Asn Cys Pro Ser Met Asp Ile Gln Ala Met Glu Glu Asn Leu Leu Arg 
            260                 265                 270         


Ile Thr Glu Thr Trp Lys Ala Tyr Asn Ser Asp Phe Glu Glu Ser Asp 
        275                 280                 285             


Glu Phe Lys Leu Phe Met Lys Arg Leu Pro Met Asn Tyr Phe Leu Asn 
    290                 295                 300                 


Thr Ser Thr Ile Met His Leu Trp Thr Met Asp Ser Asn Phe Gln Arg 
305                 310                 315                 320 


Arg Tyr Glu Gln Leu Glu Asn Ser Met Lys Gln Leu Phe Leu Lys Ala 
                325                 330                 335     


Gln Lys Ile Val His Lys Leu Phe Ser Leu Ser Lys Arg Cys His Lys 
            340                 345                 350         


Gln Pro Leu Ile Ser Leu Pro Arg Gln Arg Thr Ser Thr Tyr Trp Leu 
        355                 360                 365             


Thr Arg Ile Gln Ser Phe Leu Tyr Cys Asn Glu Asn Gly Leu Leu Gly 
    370                 375                 380                 


Ser Phe Ser Glu Glu Thr His Ser Cys Thr Cys Pro Asn Asp Gln Val 
385                 390                 395                 400 


Val Cys Thr Ala Phe Leu Pro Cys Thr Val Gly Asp Ala Ser Ala Cys 
                405                 410                 415     


Leu Thr Cys Ala Pro Asp Asn Arg Thr Arg Cys Gly Thr Cys Asn Thr 
            420                 425                 430         


Gly Tyr Met Leu Ser Gln Gly Leu Cys Lys Pro Glu Val Ala Glu Ser 
        435                 440                 445             


Thr Asp His Tyr Ile Gly Phe Glu Thr Asp Leu Gln Asp Leu Glu Met 
    450                 455                 460                 


Lys Tyr Leu Leu Gln Lys Thr Asp Arg Arg Ile Glu Val His Ala Ile 
465                 470                 475                 480 


Phe Ile Ser Asn Asp Met Arg Leu Asn Ser Trp Phe Asp Pro Ser Trp 
                485                 490                 495     


Arg Lys Arg Met Leu Leu Thr Leu Lys Ser Asn Lys Tyr Lys Ser Ser 
            500                 505                 510         


Leu Val His Met Ile Leu Gly Leu Ser Leu Gln Ile Cys Leu Thr Lys 
        515                 520                 525             


Asn Ser Thr Leu Glu Pro Val Leu Ala Val Tyr Val Asn Pro Phe Gly 
    530                 535                 540                 


Gly Ser His Ser Glu Ser Trp Phe Met Pro Val Asn Glu Asn Ser Phe 
545                 550                 555                 560 


Pro Asp Trp Glu Arg Thr Lys Leu Asp Leu Pro Leu Gln Cys Tyr Asn 
                565                 570                 575     


Trp Thr Leu Thr Leu Gly Asn Lys Trp Lys Thr Phe Phe Glu Thr Val 
            580                 585                 590         


His Ile Tyr Leu Arg Ser Arg Ile Lys Ser Asn Gly Pro Asn Gly Asn 
        595                 600                 605             


Glu Ser Ile Tyr Tyr Glu Pro Leu Glu Phe Ile Asp Pro Ser Arg Asn 
    610                 615                 620                 


Leu Gly Tyr Met Lys Ile Asn Asn Ile Gln Val Phe Gly Tyr Ser Met 
625                 630                 635                 640 


His Phe Asp Pro Glu Ala Ile Arg Asp Leu Ile Leu Gln Leu Asp Tyr 
                645                 650                 655     


Pro Tyr Thr Gln Gly Ser Gln Asp Ser Ala Leu Leu Gln Leu Leu Glu 
            660                 665                 670         


Ile Arg Asp Arg Val Asn Lys Leu Ser Pro Pro Gly Gln Arg Arg Leu 
        675                 680                 685             


Asp Leu Phe Ser Cys Leu Leu Arg His Arg Leu Lys Leu Ser Thr Ser 
    690                 695                 700                 


Glu Val Val Arg Ile Gln Ser Ala Leu Gln Ala Phe Asn Ala Lys Leu 
705                 710                 715                 720 


Pro Asn Thr Met Asp Tyr Asp Thr Thr Lys Leu Cys Ser 
                725                 730             


<210>  2579
<211>  130
<212>  PRT
<213>  Homo Sapiens

<400>  2579

Pro Asp Met Ile Arg His Leu Gln Ala Val Asp Tyr Ala Ser Arg Thr 
1               5                   10                  15      


Lys Val Phe Pro Gly Glu Arg Val Glu His Val Thr Phe Asn Phe Thr 
            20                  25                  30          


Leu Glu Asn Gln Ile His Arg Gly Gly Gln Tyr Phe Asn Asp Lys Phe 
        35                  40                  45              


Ile Gly Leu Arg Leu Lys Ser Val Ser Phe Glu Asp Ser Leu Phe Glu 
    50                  55                  60                  


Glu Cys Tyr Phe Glu Asp Val Thr Ser Ser Asn Thr Phe Phe Arg Asn 
65                  70                  75                  80  


Cys Thr Phe Ile Asn Thr Val Phe Tyr Asn Thr Asp Leu Phe Glu Tyr 
                85                  90                  95      


Lys Phe Val Asn Ser Arg Leu Ile Asn Ser Thr Phe Leu His Asn Lys 
            100                 105                 110         


Glu Gly Cys Pro Leu Asp Val Thr Gly Thr Gly Glu Gly Ala Tyr Met 
        115                 120                 125             


Val Tyr 
    130 


<210>  2580
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  2580

Pro Asp Met Ile Arg Tyr Phe Gln Asp Glu Glu Tyr Lys Ser Lys Met 
1               5                   10                  15      


Lys Val Phe Phe Gly Glu His Val Tyr Gly Ala Thr Ile Asn Phe Thr 
            20                  25                  30          


Met Glu Asn Gln Ile His Gln His Gly Lys Leu Val Asn Asp Lys Phe 
        35                  40                  45              


Thr Arg Met Tyr Phe Lys His Val Leu Phe Glu Asp Thr Phe Phe Asp 
    50                  55                  60                  


Glu Cys Tyr Phe Glu Asp Val Thr Ser Thr Asp Thr Tyr Phe Lys Asn 
65                  70                  75                  80  


Cys Thr Ile Glu Ser Thr Ile Phe Tyr Asn Thr Asp Leu Tyr Glu His 
                85                  90                  95      


Lys Phe Ile Asn Cys Arg Phe Ile Asn Ser Thr Phe Leu Glu Gln Lys 
            100                 105                 110         


Glu Gly Cys His Met Asp Leu Glu Gln Asp Asn Asp 
        115                 120                 


<210>  2581
<211>  365
<212>  PRT
<213>  Homo Sapiens

<400>  2581

Met Pro Gly Gly Lys Lys Val Ala Gly Gly Gly Ser Ser Gly Ala Thr 
1               5                   10                  15      


Pro Thr Ser Ala Ala Ala Thr Ala Pro Ser Gly Val Arg Arg Leu Glu 
            20                  25                  30          


Thr Ser Glu Gly Thr Ser Ala Gln Arg Asp Glu Glu Pro Glu Glu Glu 
        35                  40                  45              


Gly Glu Glu Asp Leu Arg Asp Gly Gly Val Pro Phe Phe Val Asn Arg 
    50                  55                  60                  


Gly Gly Leu Pro Val Asp Glu Ala Thr Trp Glu Arg Met Trp Lys His 
65                  70                  75                  80  


Val Ala Lys Ile His Pro Asp Gly Glu Lys Val Ala Gln Arg Ile Arg 
                85                  90                  95      


Gly Ala Thr Asp Leu Pro Lys Ile Pro Ile Pro Ser Val Pro Thr Phe 
            100                 105                 110         


Gln Pro Ser Thr Pro Val Pro Glu Arg Leu Glu Ala Val Gln Arg Tyr 
        115                 120                 125             


Ile Arg Glu Leu Gln Tyr Asn His Thr Gly Thr Gln Phe Phe Glu Ile 
    130                 135                 140                 


Lys Lys Ser Arg Pro Leu Thr Gly Leu Met Asp Leu Ala Lys Glu Met 
145                 150                 155                 160 


Thr Lys Glu Ala Leu Pro Ile Lys Cys Leu Glu Ala Val Ile Leu Gly 
                165                 170                 175     


Ile Tyr Leu Thr Asn Ser Met Pro Thr Leu Glu Arg Phe Pro Ile Ser 
            180                 185                 190         


Phe Lys Thr Tyr Phe Ser Gly Asn Tyr Phe Arg His Ile Val Leu Gly 
        195                 200                 205             


Val Asn Phe Ala Gly Arg Tyr Gly Ala Leu Gly Met Ser Arg Arg Glu 
    210                 215                 220                 


Asp Leu Met Tyr Lys Pro Pro Ala Phe Arg Thr Leu Ser Glu Leu Val 
225                 230                 235                 240 


Leu Asp Phe Glu Ala Ala Tyr Gly Arg Cys Trp His Val Leu Lys Lys 
                245                 250                 255     


Val Lys Leu Gly Gln Ser Val Ser His Asp Pro His Ser Val Glu Gln 
            260                 265                 270         


Ile Glu Trp Lys His Ser Val Leu Asp Val Glu Arg Leu Gly Arg Asp 
        275                 280                 285             


Asp Phe Arg Lys Glu Leu Glu Arg His Ala Arg Asp Met Arg Leu Lys 
    290                 295                 300                 


Ile Gly Lys Gly Thr Gly Pro Pro Ser Pro Thr Lys Asp Arg Lys Lys 
305                 310                 315                 320 


Asp Val Ser Ser Pro Gln Arg Ala Gln Ser Ser Pro His Arg Arg Asn 
                325                 330                 335     


Ser Arg Ser Glu Arg Arg Pro Ser Gly Asp Lys Lys Thr Ser Glu Pro 
            340                 345                 350         


Lys Ala Met Pro Asp Leu Asn Gly Tyr Gln Ile Arg Val 
        355                 360                 365 


<210>  2582
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  2582

Met Gly Ser Val Gly Ser Gln Arg Leu Glu Glu Pro Ser Val Ala Gly 
1               5                   10                  15      


Thr Pro Asp Pro Gly Val Val Met Ser Phe Thr Phe Asp Ser His Gln 
            20                  25                  30          


Leu Glu Glu Ala Ala Glu Ala Ala Gln Gly Gln Gly Leu Arg Ala Arg 
        35                  40                  45              


Gly Val Pro Ala Phe Thr Asp Thr Thr Leu Asp Glu Pro Val Pro Asp 
    50                  55                  60                  


Asp Arg Tyr His 
65              


<210>  2583
<211>  1094
<212>  PRT
<213>  Homo Sapiens

<400>  2583

Tyr Thr Val Pro Asn Ser Arg Gln Asp Leu His Pro Leu Leu Gln Asn 
1               5                   10                  15      


Met Ala Glu Glu Ile Ile Asp Gly Ser Tyr Leu Asn Ala Leu Leu Asp 
            20                  25                  30          


Leu Ile Gln Phe Gln Ser Ser His Val Trp Thr Asp Asp Leu Ser His 
        35                  40                  45              


Arg Val Leu Ala Tyr Leu Asn Ser Arg Asn Val Ala Phe Thr Ile Pro 
    50                  55                  60                  


Ser Leu Gln Ala Ala Val Glu Asn His Leu Glu Gln Arg Leu His Gln 
65                  70                  75                  80  


Pro Gln Lys Leu Leu Glu Asp Leu Arg Lys Thr Asp Ala Gln Gln Phe 
                85                  90                  95      


Arg Thr Ala Met Lys Cys Leu Leu Glu Asp Lys Lys Asp Gly Leu Asp 
            100                 105                 110         


Leu Lys Asp Ile Ile Ile Asp Leu Gly Glu Ile Arg Glu Arg Ala Leu 
        115                 120                 125             


Gln Ser Pro Gly Val Asn Arg Ser Leu Phe Leu Ile Thr Leu Glu Arg 
    130                 135                 140                 


Cys Phe Gln Met Leu Asn Ser Leu Glu Cys Val Glu Ile Leu Gly Lys 
145                 150                 155                 160 


Val Leu Arg Gly Ser Ser Gly Ser Phe Leu Gln Pro Asp Ile Thr Glu 
                165                 170                 175     


Arg Leu Pro Arg Asp Leu Arg Glu Asp Ala Phe Lys Asn Leu Ser Ala 
            180                 185                 190         


Val Phe Lys Asp Leu Tyr Asp Lys Thr Ser Ala His Ser Gln Arg Ala 
        195                 200                 205             


Leu Tyr Ser Trp Met Thr Gly Ile Leu Gln Thr Ser Ser Asn Ala Thr 
    210                 215                 220                 


Asp Asp Ser Ala Ser Trp Val Ser Ala Glu His Leu Trp Val Leu Gly 
225                 230                 235                 240 


Arg Tyr Met Val His Leu Ser Phe Glu Glu Ile Thr Lys Ile Ser Pro 
                245                 250                 255     


Ile Glu Ile Gly Leu Phe Ile Ser Tyr Asp Asn Ala Thr Lys Gln Leu 
            260                 265                 270         


Asp Met Val Tyr Asp Ile Thr Pro Glu Leu Ala Gln Ala Phe Leu Glu 
        275                 280                 285             


Arg Ile Ser Ser Ser Asn Phe Asn Met Arg Asn Thr Ser Thr Ile His 
    290                 295                 300                 


Arg Leu Gly Leu Leu Val Cys Phe Tyr Asn Asp Leu Glu Leu Leu Asp 
305                 310                 315                 320 


Ala Thr Val Ala Gln Val Leu Leu Tyr Gln Met Ile Lys Cys Ser His 
                325                 330                 335     


Leu Arg Gly Phe Gln Ala Gly Val Gln Lys Leu Lys Ala Glu Leu Leu 
            340                 345                 350         


Asp Ile Ala Met Glu Asn Gln Thr Leu Asn Glu Thr Leu Gly Ser Leu 
        355                 360                 365             


Ser Asp Ala Val Val Gly Leu Thr Tyr Ser Gln Leu Glu Ser Leu Ser 
    370                 375                 380                 


Pro Glu Ala Val His Gly Ala Ile Ser Thr Leu Asn Gln Val Ser Gly 
385                 390                 395                 400 


Trp Ala Lys Ser Gln Val Ile Ile Leu Ser Ala Lys Tyr Leu Ala His 
                405                 410                 415     


Glu Lys Val Leu Ser Phe Tyr Asn Val Ser Gln Met Gly Ala Leu Leu 
            420                 425                 430         


Ala Gly Val Ser Thr Gln Ala Phe Cys Ser Met Lys Arg Lys Asp Ile 
        435                 440                 445             


Ser Gln Val Leu Arg Ser Ala Val Ser Gln Tyr Val Ser Asp Leu Ser 
    450                 455                 460                 


Pro Ala Gln Gln Gln Gly Ile Leu Ser Lys Met Val Gln Ala Glu Asp 
465                 470                 475                 480 


Thr Ala Pro Gly Ile Val Glu Ile Gln Gly Ala Phe Phe Lys Glu Val 
                485                 490                 495     


Ser Leu Phe Asp Leu Arg Arg Gln Pro Gly Phe Asn Ser Thr Val Leu 
            500                 505                 510         


Lys Asp Lys Glu Leu Gly Arg Ser Gln Ala Leu Phe Leu Tyr Glu Leu 
        515                 520                 525             


Leu Leu Lys Thr Thr Arg Arg Pro Glu Glu Leu Leu Ser Ala Gly Gln 
    530                 535                 540                 


Leu Val Lys Gly Val Thr Cys Ser His Ile Asp Ala Met Ser Thr Asp 
545                 550                 555                 560 


Phe Phe Leu Ala His Phe Gln Asp Phe Gln Asn Asn Phe Ala Leu Leu 
                565                 570                 575     


Ser Pro Tyr Gln Val Asn Cys Leu Ala Trp Lys Tyr Trp Glu Val Ser 
            580                 585                 590         


Arg Leu Ser Met Pro Pro Phe Leu Leu Ala Ala Leu Pro Ala Arg Tyr 
        595                 600                 605             


Leu Ala Ser Val Pro Ala Ser Gln Cys Val Pro Phe Leu Ile Ser Leu 
    610                 615                 620                 


Gly Lys Ser Trp Leu Asp Ser Leu Val Leu Asp Ser His Lys Lys Thr 
625                 630                 635                 640 


Ser Val Leu Arg Lys Val Gln Gln Cys Leu Asp Asp Ser Ile Ala Asp 
                645                 650                 655     


Glu Tyr Thr Val Asp Ile Met Gly Asn Leu Leu Cys His Leu Pro Ala 
            660                 665                 670         


Ala Ile Ile Asp Arg Gly Ile Ser Pro Arg Ala Trp Ala Thr Ala Leu 
        675                 680                 685             


His Gly Leu Arg Asp Cys Pro Asp Leu Asn Pro Glu Gln Lys Ala Ala 
    690                 695                 700                 


Val Arg Leu Lys Leu Leu Gly Gln Tyr Gly Leu Pro Gln His Trp Thr 
705                 710                 715                 720 


Ala Glu Thr Thr Lys Asp Leu Gly Pro Phe Leu Val Leu Phe Ser Gly 
                725                 730                 735     


Asp Glu Leu Ser Ser Ile Ala Thr Lys Phe Pro Glu Ile Leu Leu Gln 
            740                 745                 750         


Ala Ala Ser Lys Met Ala Arg Thr Leu Pro Thr Lys Glu Phe Leu Trp 
        755                 760                 765             


Ala Val Phe Gln Ser Val Arg Asn Ser Ser Asp Lys Ile Pro Ser Tyr 
    770                 775                 780                 


Asp Pro Met Pro Gly Cys His Gly Val Val Ala Pro Ser Ser Asp Asp 
785                 790                 795                 800 


Ile Phe Lys Leu Ala Glu Ala Asn Ala Cys Trp Ala Leu Glu Asp Leu 
                805                 810                 815     


Arg Cys Met Glu Glu Asp Thr Phe Ile Arg Thr Val Glu Leu Leu Gly 
            820                 825                 830         


Ala Val Gln Gly Phe Ser Arg Pro Gln Leu Met Thr Leu Lys Glu Lys 
        835                 840                 845             


Ala Ile Gln Val Trp Asp Met Pro Ser Tyr Trp Arg Glu His His Ile 
    850                 855                 860                 


Val Ser Leu Gly Arg Ile Ala Leu Ala Leu Asn Glu Ser Glu Leu Glu 
865                 870                 875                 880 


Gln Leu Asp Leu Ser Ser Ile Asp Thr Val Ala Ser Leu Ser Trp Gln 
                885                 890                 895     


Thr Glu Trp Thr Pro Gly Gln Ala Glu Ser Ile Leu Gln Gly Tyr Leu 
            900                 905                 910         


Asp Asp Ser Gly Tyr Ser Ile Gln Asp Leu Lys Ser Phe His Leu Val 
        915                 920                 925             


Gly Leu Gly Ala Thr Leu Cys Ala Ile Asn Ile Thr Glu Ile Pro Leu 
    930                 935                 940                 


Ile Lys Ile Ser Glu Phe Arg Val Val Val Ala Arg Ile Gly Thr Leu 
945                 950                 955                 960 


Leu Cys Ser Thr His Val Leu Ala Glu Phe Lys Arg Lys Ala Glu Val 
                965                 970                 975     


Val Phe Gly Asp Pro Thr Glu Trp Thr Ser Ser Val Leu Gln Glu Leu 
            980                 985                 990         


Gly Thr Ile Ala Ala Gly Leu Thr  Lys Ala Ala Leu Arg  Met Leu Asp 
        995                 1000                 1005             


Lys Asp  Leu Met Pro Tyr Phe  Gln Pro Ser Ala Ile  Lys Cys Leu 
    1010                 1015                 1020             


Pro Asp  Glu Ile Phe Lys Glu  Leu Ser Ala Glu Gln  Ile Ala Ser 
    1025                 1030                 1035             


Leu Gly  Pro Glu Asn Ala Ala  Ala Val Thr His Ala  Gln Arg Arg 
    1040                 1045                 1050             


Arg Leu  Ser Pro Leu Gln Leu  Gln Ser Leu Gln Gln  Ala Leu Asp 
    1055                 1060                 1065             


Gly Ala  Lys Thr His Ser Trp  Gln Asp Ala Pro Ala  Ser Ala Gly 
    1070                 1075                 1080             


Pro Thr  Arg Thr Ser Ser Ser  Arg Ser Pro Ala 
    1085                 1090                 


<210>  2584
<211>  550
<212>  PRT
<213>  Homo Sapiens

<400>  2584

Ala Pro Leu Cys Leu Ser Gln Gln Leu Arg Met Lys Gly Asp Tyr Val 
1               5                   10                  15      


Leu Gly Gly Leu Phe Pro Leu Gly Glu Ala Glu Glu Ala Gly Leu Arg 
            20                  25                  30          


Ser Arg Thr Arg Pro Ser Ser Pro Val Cys Thr Arg Phe Ser Ser Asn 
        35                  40                  45              


Gly Leu Leu Trp Ala Leu Ala Met Lys Met Ala Val Glu Glu Ile Asn 
    50                  55                  60                  


Asn Lys Ser Asp Leu Leu Pro Gly Leu Arg Leu Gly Tyr Asp Leu Phe 
65                  70                  75                  80  


Asp Thr Cys Ser Glu Pro Val Val Ala Met Lys Pro Ser Leu Met Phe 
                85                  90                  95      


Leu Ala Lys Ala Gly Ser Arg Asp Ile Ala Ala Tyr Cys Asn Tyr Thr 
            100                 105                 110         


Gln Tyr Gln Pro Arg Val Leu Ala Val Ile Gly Pro His Ser Ser Glu 
        115                 120                 125             


Leu Ala Met Val Thr Gly Lys Phe Phe Ser Phe Phe Leu Met Pro Gln 
    130                 135                 140                 


Val Ser Tyr Gly Ala Ser Met Glu Leu Leu Ser Ala Arg Glu Thr Phe 
145                 150                 155                 160 


Pro Ser Phe Phe Arg Thr Val Pro Ser Asp Arg Val Gln Leu Thr Ala 
                165                 170                 175     


Ala Ala Glu Leu Leu Gln Glu Phe Gly Trp Asn Trp Val Ala Ala Leu 
            180                 185                 190         


Gly Ser Asp Asp Glu Tyr Gly Arg Gln Gly Leu Ser Ile Phe Ser Ala 
        195                 200                 205             


Leu Ala Ala Ala Arg Gly Ile Cys Ile Ala His Glu Gly Leu Val Pro 
    210                 215                 220                 


Leu Pro Arg Ala Asp Asp Ser Arg Leu Gly Lys Val Gln Asp Val Leu 
225                 230                 235                 240 


His Gln Val Asn Gln Ser Ser Val Gln Val Val Leu Leu Phe Ala Ser 
                245                 250                 255     


Val His Ala Ala His Ala Leu Phe Asn Tyr Ser Ile Ser Ser Arg Leu 
            260                 265                 270         


Ser Pro Lys Val Trp Val Ala Ser Glu Ala Trp Leu Thr Ser Asp Leu 
        275                 280                 285             


Val Met Gly Leu Pro Gly Met Ala Gln Met Gly Thr Val Leu Gly Phe 
    290                 295                 300                 


Leu Gln Arg Gly Ala Gln Leu His Glu Phe Pro Gln Tyr Val Lys Thr 
305                 310                 315                 320 


His Leu Ala Leu Ala Thr Asp Pro Ala Phe Cys Ser Ala Leu Gly Glu 
                325                 330                 335     


Arg Glu Gln Gly Leu Glu Glu Asp Val Val Gly Gln Arg Cys Pro Gln 
            340                 345                 350         


Cys Asp Cys Ile Thr Leu Gln Asn Val Ser Ala Gly Leu Asn His His 
        355                 360                 365             


Gln Thr Phe Ser Val Tyr Ala Ala Val Tyr Ser Val Ala Gln Ala Leu 
    370                 375                 380                 


His Asn Thr Leu Gln Cys Asn Ala Ser Gly Cys Pro Ala Gln Asp Pro 
385                 390                 395                 400 


Val Lys Pro Trp Gln Leu Leu Glu Asn Met Tyr Asn Leu Thr Phe His 
                405                 410                 415     


Val Gly Gly Leu Pro Leu Arg Phe Asp Ser Ser Gly Asn Val Asp Met 
            420                 425                 430         


Glu Tyr Asp Leu Lys Leu Trp Val Trp Gln Gly Ser Val Pro Arg Leu 
        435                 440                 445             


His Asp Val Gly Arg Phe Asn Gly Ser Leu Arg Thr Glu Arg Leu Lys 
    450                 455                 460                 


Ile Arg Trp His Thr Ser Asp Asn Gln Lys Pro Val Ser Arg Cys Ser 
465                 470                 475                 480 


Arg Gln Cys Gln Glu Gly Gln Val Arg Arg Val Lys Gly Phe His Ser 
                485                 490                 495     


Cys Cys Tyr Asp Cys Val Asp Cys Glu Ala Gly Ser Tyr Arg Gln Asn 
            500                 505                 510         


Pro Asp Asp Ile Ala Cys Thr Phe Cys Gly Gln Asp Glu Trp Ser Pro 
        515                 520                 525             


Glu Arg Ser Thr Arg Cys Phe Arg Arg Arg Ser Arg Phe Leu Ala Trp 
    530                 535                 540                 


Gly Glu Pro Ala Val Leu 
545                 550 


<210>  2585
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  2585

Gln Pro Val Tyr Ser Ser Arg Val Val Gly Gly Gln Asp Ala Ala Ala 
1               5                   10                  15      


Gly Arg Trp Pro Trp Gln Val Ser Leu His Phe Asp His Asn Phe Ile 
            20                  25                  30          


Tyr Gly Gly Ser Leu Val Ser Glu Arg Leu Ile Leu Thr Ala Ala His 
        35                  40                  45              


Cys Ile Gln Pro Thr Trp Thr Thr Phe Ser Tyr Thr Val Trp Leu Gly 
    50                  55                  60                  


Ser Ile Thr Val Gly Asp Ser Arg Lys Arg Val Lys Tyr Tyr Val Ser 
65                  70                  75                  80  


Lys Ile Val Ile His Pro Lys Tyr Gln Asp Thr Thr Ala Asp Val Ala 
                85                  90                  95      


Leu Leu Lys Leu Ser Ser Gln Val Thr Phe Thr Ser Ala Ile Leu Pro 
            100                 105                 110         


Ile Cys Leu Pro Ser Val Thr Lys Gln Leu Ala Ile Pro Pro Phe Cys 
        115                 120                 125             


Trp Val Thr Gly Trp Gly Lys Val Lys Glu Ser Ser Asp Arg Asp Tyr 
    130                 135                 140                 


His Ser Ala Leu Gln Glu Ala Glu Val Pro Ile Ile Asp Arg Gln Ala 
145                 150                 155                 160 


Cys Glu Gln Leu Tyr Asn Pro Ile Gly Ile Phe Leu Pro Ala Leu Glu 
                165                 170                 175     


Pro Val Ile Lys Glu Asp Lys Ile Cys Ala Gly Asp Thr Gln Asn Met 
            180                 185                 190         


Lys Asp Ser Cys Lys Gly Asp Ser Gly Gly Pro Leu Ser Cys His Ile 
        195                 200                 205             


Asp Gly Val Trp Ile Gln Thr Gly Val Val Ser Trp Gly Leu Glu Cys 
    210                 215                 220                 


Gly Lys Ser Leu Pro Gly Val Tyr Thr Asn Val Ile Tyr Tyr Gln Lys 
225                 230                 235                 240 


Trp Ile Asn Ala Thr Ile Ser Arg Ala Asn Asn Leu Asp Phe Ser Asp 
                245                 250                 255     


Phe Leu Phe Pro Ile Val Leu Leu Ser Leu Ala Leu Leu Cys Pro Ser 
            260                 265                 270         


Cys Ala Phe Gly Pro Asn Thr Ile His Arg Val Gly Thr Val Ala Glu 
        275                 280                 285             


Ala Val Ala Cys Ile Gln Gly Trp Glu Glu Asn Ala Trp Arg Phe Ser 
    290                 295                 300                 


Pro Arg Gly Arg 
305             


<210>  2586
<211>  1088
<212>  PRT
<213>  Homo Sapiens

<400>  2586

Ile Ser Ser Trp Arg Asn Ser Thr Val Thr Gly His Pro Trp Gln Val 
1               5                   10                  15      


Ser Leu Lys Ser Asp Glu His His Phe Cys Gly Gly Ser Leu Ile Gln 
            20                  25                  30          


Glu Asp Arg Val Val Thr Ala Ala His Cys Leu Asp Ser Leu Ser Glu 
        35                  40                  45              


Lys Gln Leu Lys Asn Ile Thr Val Thr Ser Gly Glu Tyr Ser Leu Phe 
    50                  55                  60                  


Gln Lys Asp Lys Gln Glu Gln Asn Ile Pro Val Ser Lys Ile Ile Thr 
65                  70                  75                  80  


His Pro Glu Tyr Asn Ser Arg Glu Tyr Met Ser Pro Asp Ile Ala Leu 
                85                  90                  95      


Leu Tyr Leu Lys His Lys Val Lys Phe Gly Asn Ala Val Gln Pro Ile 
            100                 105                 110         


Cys Leu Pro Asp Ser Asp Asp Lys Val Glu Pro Gly Ile Leu Cys Leu 
        115                 120                 125             


Ser Ser Gly Trp Gly Lys Ile Ser Lys Thr Ser Glu Tyr Ser Asn Val 
    130                 135                 140                 


Leu Gln Glu Met Glu Leu Pro Ile Met Asp Asp Arg Ala Cys Asn Thr 
145                 150                 155                 160 


Val Leu Lys Ser Met Asn Leu Pro Pro Leu Gly Arg Thr Met Leu Cys 
                165                 170                 175     


Ala Gly Phe Pro Asp Trp Gly Met Asp Ala Cys Gln Gly Asp Ser Gly 
            180                 185                 190         


Gly Pro Leu Val Cys Arg Arg Gly Gly Gly Ile Trp Ile Leu Ala Gly 
        195                 200                 205             


Ile Thr Ser Trp Val Ala Gly Cys Ala Gly Gly Ser Val Pro Val Arg 
    210                 215                 220                 


Asn Asn His Val Lys Ala Ser Leu Gly Ile Phe Ser Lys Val Ser Glu 
225                 230                 235                 240 


Leu Met Asp Phe Ile Thr Gln Asn Leu Phe Thr Gly Leu Asp Arg Gly 
                245                 250                 255     


Gln Pro Leu Ser Lys Val Gly Ser Arg Tyr Ile Thr Lys Ala Leu Ser 
            260                 265                 270         


Ser Val Gln Glu Val Asn Gly Ser Gln Arg Gly Lys Gly Ile Leu Asp 
        275                 280                 285             


Met Glu Lys Gln Val Gly Cys Asp His Asp Tyr Val Ser Leu Arg Ser 
    290                 295                 300                 


Ser Ser Gly Val Leu Phe Asn Gln Arg Ser Leu Met Glu Asp Asp Gly 
305                 310                 315                 320 


Lys Gln Asn Lys Arg Val Cys Gly Lys Ile Leu Pro Ser Pro Leu Leu 
                325                 330                 335     


Ala Glu Thr Ser Glu Ala Met Val Pro Phe Val Ser Asp Thr Glu Asp 
            340                 345                 350         


Ser Gly Ser Gly Phe Glu Leu Thr Val Thr Ala Val Gln Lys Ser Glu 
        355                 360                 365             


Ala Gly Ser Gly Cys Gly Ser Leu Ala Ile Leu Val Glu Glu Gly Thr 
    370                 375                 380                 


Asn His Ser Ala Lys Tyr Pro Asp Leu Tyr Pro Ser Asn Thr Arg Cys 
385                 390                 395                 400 


His Trp Phe Ile Cys Ala Pro Glu Lys His Ile Ile Lys Leu Thr Phe 
                405                 410                 415     


Glu Asp Phe Ala Val Lys Phe Ser Pro Asn Cys Ile Tyr Asp Ala Val 
            420                 425                 430         


Val Ile Tyr Gly Asp Ser Glu Glu Lys His Lys Leu Ala Lys Leu Cys 
        435                 440                 445             


Gly Met Leu Thr Ile Thr Ser Ile Phe Ser Ser Ser Asn Met Thr Val 
    450                 455                 460                 


Ile Tyr Phe Lys Ser Asp Gly Lys Asn Arg Leu Gln Gly Phe Lys Ala 
465                 470                 475                 480 


Arg Phe Thr Ile Leu Pro Ser Glu Ser Leu Asn Lys Phe Glu Pro Lys 
                485                 490                 495     


Leu Pro Pro Gln Asn Asn Pro Val Ser Thr Val Lys Ala Ile Leu His 
            500                 505                 510         


Asp Val Cys Gly Ile Pro Pro Phe Ser Pro Gln Trp Leu Ser Arg Arg 
        515                 520                 525             


Ile Ala Gly Gly Glu Glu Ala Cys Pro His Cys Trp Pro Trp Gln Val 
    530                 535                 540                 


Gly Leu Arg Phe Leu Gly Asp Tyr Gln Cys Gly Gly Ala Ile Ile Asn 
545                 550                 555                 560 


Pro Val Trp Ile Leu Thr Ala Ala His Cys Val Gln Leu Lys Asn Asn 
                565                 570                 575     


Pro Leu Ser Trp Thr Ile Ile Ala Gly Asp His Asp Arg Asn Leu Lys 
            580                 585                 590         


Glu Ser Thr Glu Gln Val Arg Arg Ala Lys His Ile Ile Val His Glu 
        595                 600                 605             


Asp Phe Asn Thr Leu Ser Tyr Asp Ser Asp Ile Ala Leu Ile Gln Leu 
    610                 615                 620                 


Ser Ser Pro Leu Glu Tyr Asn Ser Val Val Arg Pro Val Cys Leu Pro 
625                 630                 635                 640 


His Ser Ala Glu Pro Leu Phe Ser Ser Glu Ile Cys Ala Val Thr Gly 
                645                 650                 655     


Trp Gly Ser Ile Ser Ala Asp Gly Gly Leu Ala Ser Arg Leu Gln Gln 
            660                 665                 670         


Ile Gln Val His Val Leu Glu Arg Glu Val Cys Glu His Thr Tyr Tyr 
        675                 680                 685             


Ser Ala His Pro Gly Gly Ile Thr Glu Lys Met Ile Cys Ala Gly Phe 
    690                 695                 700                 


Ala Ala Ser Gly Glu Lys Asp Phe Cys Gln Gly Asp Ser Gly Gly Pro 
705                 710                 715                 720 


Leu Val Cys Arg His Glu Asn Gly Pro Phe Val Leu Tyr Gly Ile Val 
                725                 730                 735     


Ser Trp Gly Ala Gly Cys Val Gln Pro Trp Lys Pro Gly Val Phe Ala 
            740                 745                 750         


Arg Val Met Ile Phe Leu Asp Trp Ile Gln Ser Lys Ile Asn Gly Pro 
        755                 760                 765             


Ala Ser Leu Gln Thr Asn Asn Lys Cys Lys Thr Leu Lys Gln Gln Leu 
    770                 775                 780                 


Pro Pro Pro Thr Pro Ser Pro Asp Ser Ala Ser Trp Pro Gly Cys Cys 
785                 790                 795                 800 


Ser Glu Ala Glu Leu Glu Lys Pro Arg Gly Phe Phe Pro Thr Pro Arg 
                805                 810                 815     


Tyr Leu Leu Asp Tyr Arg Gly Arg Leu Glu Cys Ser Trp Val Leu Arg 
            820                 825                 830         


Val Ser Ala Ser Ser Met Ala Lys Phe Thr Ile Glu Tyr Leu Ser Leu 
        835                 840                 845             


Leu Gly Ser Pro Val Cys Gln Asp Ser Val Leu Ile Ile Tyr Glu Glu 
    850                 855                 860                 


Arg His Ser Lys Arg Lys Thr Ala Gly Gly Leu His Gly Arg Arg Leu 
865                 870                 875                 880 


Tyr Ser Met Thr Phe Met Ser Pro Gly Pro Leu Val Arg Val Thr Phe 
                885                 890                 895     


His Ala Leu Val Arg Gly Ala Phe Gly Ile Ser Tyr Ile Val Leu Lys 
            900                 905                 910         


Val Leu Gly Pro Lys Asp Ser Lys Ile Thr Arg Leu Ser Gln Ser Ser 
        915                 920                 925             


Asn Arg Glu His Leu Val Pro Cys Glu Asp Val Leu Leu Thr Lys Pro 
    930                 935                 940                 


Glu Gly Ile Met Gln Ile Pro Arg Asn Ser His Arg Thr Thr Met Gly 
945                 950                 955                 960 


Cys Gln Trp Arg Leu Val Ala Pro Leu Asn His Ile Ile Gln Leu Asn 
                965                 970                 975     


Ile Ile Asn Phe Pro Met Lys Pro Thr Thr Phe Val Cys His Gly His 
            980                 985                 990         


Leu Arg Val Tyr Glu Gly Phe Gly  Pro Gly Lys Lys Leu  Ile Ala Ser 
        995                 1000                 1005             


Phe Ala  Gly Thr Leu Ala Met  Ile Leu Thr Lys Asp  Ile Leu Lys 
    1010                 1015                 1020             


Arg Glu  Lys Leu Asn Phe Ile  Asn Thr Tyr Ile Met  His Ile Trp 
    1025                 1030                 1035             


Glu Asn  Ser Val Tyr Asp Asn  Val Arg Ser Val Gly  Lys Arg Lys 
    1040                 1045                 1050             


Gln Lys  Lys Phe Ala Ser Asn  Leu Ser Tyr Ser Met  Glu Ala Glu 
    1055                 1060                 1065             


Lys Ser  Arg Ile Gln Val Pro  Ala Asp Leu Val Pro  Ala Lys Gly 
    1070                 1075                 1080             


Ser Leu  Ser Gly Ser 
    1085             


<210>  2587
<211>  668
<212>  PRT
<213>  Homo Sapiens

<400>  2587

Leu Asp Leu Pro Ala Gly Ser Cys Ala Phe Glu Glu Ser Thr Cys Gly 
1               5                   10                  15      


Phe Asp Ser Val Leu Ala Ser Leu Pro Trp Ile Leu Asn Glu Glu Gly 
            20                  25                  30          


His Tyr Ile Tyr Val Asp Thr Ser Phe Gly Lys Gln Gly Glu Lys Ala 
        35                  40                  45              


Val Leu Leu Ser Pro Asp Leu Gln Ala Glu Glu Trp Ser Cys Leu Arg 
    50                  55                  60                  


Leu Val Tyr Gln Ile Thr Thr Ser Ser Glu Ser Leu Ser Asp Pro Ser 
65                  70                  75                  80  


Gln Leu Asn Leu Tyr Met Arg Phe Glu Asp Glu Ser Phe Asp Arg Leu 
                85                  90                  95      


Leu Trp Ser Ala Lys Glu Pro Ser Asp Ser Trp Leu Ile Ala Ser Leu 
            100                 105                 110         


Asp Leu Gln Asn Ser Ser Lys Lys Phe Lys Ile Leu Ile Glu Gly Val 
        115                 120                 125             


Leu Gly Gln Gly Asn Thr Ala Ser Ile Ala Leu Phe Glu Ile Lys Met 
    130                 135                 140                 


Thr Thr Gly Tyr Cys Ile Glu Cys Asp Phe Glu Glu Asn His Leu Cys 
145                 150                 155                 160 


Gly Phe Val Asn Arg Trp Asn Pro Asn Val Asn Trp Phe Val Gly Gly 
                165                 170                 175     


Gly Ser Ile Arg Asn Val His Ser Ile Leu Pro Gln Asp His Thr Phe 
            180                 185                 190         


Lys Ser Glu Leu Gly His Tyr Met Tyr Val Asp Ser Val Tyr Val Lys 
        195                 200                 205             


His Phe Gln Glu Val Ala Gln Leu Ile Ser Pro Leu Thr Thr Ala Pro 
    210                 215                 220                 


Met Ala Gly Cys Leu Ser Phe Tyr Tyr Gln Ile Gln Gln Gly Asn Asp 
225                 230                 235                 240 


Asn Val Phe Ser Leu Tyr Thr Arg Asp Val Ala Gly Leu Tyr Glu Glu 
                245                 250                 255     


Ile Trp Lys Ala Asp Arg Pro Gly Asn Ala Ala Trp Asn Leu Ala Glu 
            260                 265                 270         


Val Glu Phe Asn Ala Pro Tyr Pro Met Glu Val Ile Phe Glu Val Ala 
        275                 280                 285             


Phe Asn Gly Pro Lys Gly Gly Tyr Val Ala Leu Asp Asp Ile Ser Phe 
    290                 295                 300                 


Ser Pro Val His Cys Gln Asn Gln Thr Glu Leu Leu Phe Ser Ala Val 
305                 310                 315                 320 


Glu Ala Ser Cys Asn Phe Glu Gln Asp Leu Cys Asn Phe Tyr Gln Asp 
                325                 330                 335     


Lys Glu Gly Pro Gly Trp Thr Arg Val Lys Val Lys Pro Asn Met Tyr 
            340                 345                 350         


Arg Ala Gly Asp His Thr Thr Gly Leu Gly Tyr Tyr Leu Leu Ala Asn 
        355                 360                 365             


Thr Lys Phe Thr Ser Gln Pro Gly Tyr Ile Gly Arg Leu Tyr Gly Pro 
    370                 375                 380                 


Ser Leu Pro Gly Asn Leu Gln Tyr Cys Leu Arg Phe His Tyr Ala Ile 
385                 390                 395                 400 


Tyr Gly Phe Leu Lys Met Ser Asp Thr Leu Ala Val Tyr Ile Phe Glu 
                405                 410                 415     


Glu Asn His Val Val Gln Glu Lys Ile Trp Ser Val Leu Glu Ser Pro 
            420                 425                 430         


Arg Gly Val Trp Met Gln Ala Glu Ile Thr Phe Lys Lys Pro Met Pro 
        435                 440                 445             


Thr Lys Val Val Phe Met Ser Leu Cys Lys Ser Phe Trp Asp Cys Gly 
    450                 455                 460                 


Leu Val Ala Leu Asp Asp Ile Thr Ile Gln Leu Gly Ser Cys Ser Ser 
465                 470                 475                 480 


Ser Glu Lys Leu Pro Pro Pro Pro Gly Glu Cys Thr Phe Glu Gln Asp 
                485                 490                 495     


Glu Cys Thr Phe Thr Gln Glu Lys Arg Asn Arg Ser Ser Trp His Arg 
            500                 505                 510         


Arg Arg Gly Glu Thr Pro Thr Ser Tyr Thr Gly Pro Lys Gly Asp His 
        515                 520                 525             


Thr Thr Gly Val Gly Tyr Tyr Met Tyr Ile Glu Ala Ser His Met Val 
    530                 535                 540                 


Tyr Gly Gln Lys Ala Arg Leu Leu Ser Arg Pro Leu Arg Gly Val Ser 
545                 550                 555                 560 


Gly Lys His Cys Leu Thr Phe Phe Tyr His Met Tyr Gly Gly Gly Thr 
                565                 570                 575     


Gly Leu Leu Ser Val Tyr Leu Lys Lys Glu Glu Asp Ser Glu Glu Ser 
            580                 585                 590         


Leu Leu Trp Arg Arg Arg Gly Glu Gln Ser Ile Ser Trp Leu Arg Ala 
        595                 600                 605             


Leu Ile Glu Tyr Ser Cys Glu Arg Gln His Gln Ile Ile Phe Glu Ala 
    610                 615                 620                 


Ile Arg Gly Val Ser Ile Arg Ser Asp Ile Ala Ile Asp Asp Val Lys 
625                 630                 635                 640 


Phe Gln Ala Gly Pro Cys Gly Glu Met Glu Asp Thr Thr Gln Gln Ser 
                645                 650                 655     


Ser Gly Tyr Ser Glu Asp Leu Asn Glu Ile Glu Tyr 
            660                 665             


<210>  2588
<211>  217
<212>  PRT
<213>  Homo Sapiens

<400>  2588

Met Ala Gly Arg His Gln Asn Arg Ser Phe Pro Leu Pro Gly Val Gln 
1               5                   10                  15      


Ser Ser Gly Gln Val His Ala Phe Gly Asn Cys Ser Asp Ser Asp Ile 
            20                  25                  30          


Leu Glu Glu Asp Ala Glu Val Tyr Glu Leu Arg Ser Arg Gly Lys Glu 
        35                  40                  45              


Lys Val Arg Arg Ser Thr Ser Arg Asp Arg Leu Asp Asp Ile Ile Val 
    50                  55                  60                  


Leu Thr Lys Asp Ile Gln Glu Gly Asp Thr Leu Asn Ala Ile Ala Leu 
65                  70                  75                  80  


Gln Tyr Cys Cys Thr Val Ala Asp Ile Lys Arg Val Asn Asn Leu Ile 
                85                  90                  95      


Ser Asp Gln Asp Phe Phe Ala Leu Arg Ser Ile Lys Ile Pro Val Lys 
            100                 105                 110         


Lys Phe Ser Ser Leu Thr Glu Thr Leu Cys Pro Pro Lys Gly Arg Gln 
        115                 120                 125             


Thr Ser Arg His Ser Ser Val Gln Tyr Ser Ser Glu Gln Gln Glu Ile 
    130                 135                 140                 


Leu Pro Ala Asn Asp Ser Leu Ala Tyr Ser Asp Ser Ala Gly Ser Phe 
145                 150                 155                 160 


Leu Lys Glu Val Asp Arg Asp Ile Glu Gln Ile Val Lys Cys Thr Asp 
                165                 170                 175     


Asn Lys Arg Glu Asn Leu Asn Glu Val Val Ser Ala Leu Thr Ala Gln 
            180                 185                 190         


Gln Met Arg Phe Glu Pro Asp Asn Lys Asn Thr Gln Arg Lys Asp Pro 
        195                 200                 205             


Tyr Tyr Gly Ala Asp Trp Gly Ile Gly 
    210                 215         


<210>  2589
<211>  1096
<212>  PRT
<213>  Homo Sapiens

<400>  2589

Ala Thr Pro Asn Phe Leu Ala Asn Pro Ser Ser Ser Ser Arg Trp Ile 
1               5                   10                  15      


Pro Leu Gln Pro Met Pro Val Ala Trp Ala Phe Val Gln Lys Thr Ser 
            20                  25                  30          


Ala Leu Leu Trp Leu Leu Leu Leu Gly Thr Ser Leu Ser Pro Ala Trp 
        35                  40                  45              


Gly Gln Ala Lys Ile Pro Leu Glu Thr Val Lys Leu Trp Ala Asp Thr 
    50                  55                  60                  


Phe Gly Gly Asp Leu Tyr Asn Thr Val Thr Lys Tyr Ser Gly Ser Leu 
65                  70                  75                  80  


Leu Leu Gln Lys Lys Tyr Lys Asp Val Glu Ser Ser Leu Lys Ile Glu 
                85                  90                  95      


Glu Val Asp Gly Leu Glu Leu Val Arg Lys Phe Ser Glu Asp Met Glu 
            100                 105                 110         


Asn Met Leu Arg Arg Lys Val Glu Ala Val Gln Asn Leu Val Glu Ala 
        115                 120                 125             


Ala Glu Glu Ala Asp Leu Asn His Glu Phe Asn Glu Ser Leu Val Phe 
    130                 135                 140                 


Asp Tyr Tyr Asn Ser Val Leu Ile Asn Glu Arg Asp Glu Lys Gly Asn 
145                 150                 155                 160 


Phe Val Glu Leu Gly Ala Glu Phe Leu Leu Glu Ser Asn Ala His Phe 
                165                 170                 175     


Ser Asn Leu Pro Val Asn Thr Ser Ile Ser Ser Val Gln Leu Pro Thr 
            180                 185                 190         


Asn Val Tyr Asn Lys Asp Pro Asp Ile Leu Asn Gly Val Tyr Met Ser 
        195                 200                 205             


Glu Ala Leu Asn Ala Val Phe Val Glu Asn Phe Gln Arg Asp Pro Thr 
    210                 215                 220                 


Leu Thr Trp Gln Tyr Phe Gly Ser Ala Thr Gly Phe Phe Arg Ile Tyr 
225                 230                 235                 240 


Pro Gly Ile Lys Trp Thr Pro Asp Glu Asn Gly Val Ile Thr Phe Asp 
                245                 250                 255     


Cys Arg Asn Arg Gly Trp Tyr Ile Gln Ala Ala Thr Ser Pro Lys Asp 
            260                 265                 270         


Ile Val Ile Leu Val Asp Val Ser Gly Ser Met Lys Gly Leu Arg Met 
        275                 280                 285             


Thr Ile Ala Lys His Thr Ile Thr Thr Ile Leu Asp Thr Leu Gly Glu 
    290                 295                 300                 


Asn Asp Phe Val Asn Ile Ile Ala Tyr Asn Asp Tyr Val His Tyr Ile 
305                 310                 315                 320 


Glu Pro Cys Phe Lys Gly Ile Leu Val Gln Ala Asp Arg Asp Asn Arg 
                325                 330                 335     


Glu His Phe Lys Leu Leu Val Glu Glu Leu Met Val Lys Gly Val Gly 
            340                 345                 350         


Val Val Asp Gln Ala Leu Arg Glu Ala Phe Gln Ile Leu Lys Gln Phe 
        355                 360                 365             


Gln Glu Ala Lys Gln Gly Ser Leu Cys Asn Gln Ala Ile Met Leu Ile 
    370                 375                 380                 


Ser Asp Gly Ala Val Glu Asp Tyr Glu Pro Val Phe Glu Lys Tyr Asn 
385                 390                 395                 400 


Trp Pro Asp Cys Lys Val Arg Val Phe Thr Tyr Leu Ile Gly Arg Glu 
                405                 410                 415     


Val Ser Phe Ala Asp Arg Met Lys Trp Ile Ala Cys Asn Asn Lys Gly 
            420                 425                 430         


Tyr Tyr Thr Gln Ile Ser Thr Leu Ala Asp Thr Gln Glu Asn Val Met 
        435                 440                 445             


Glu Tyr Leu His Val Leu Ser Arg Pro Met Val Ile Asn His Asp His 
    450                 455                 460                 


Asp Ile Ile Trp Thr Glu Ala Tyr Met Asp Ser Lys Leu Leu Ser Ser 
465                 470                 475                 480 


Gln Ala Gln Ser Leu Thr Leu Leu Thr Thr Val Ala Met Pro Val Phe 
                485                 490                 495     


Ser Lys Lys Asn Glu Thr Arg Ser His Gly Ile Leu Leu Gly Val Val 
            500                 505                 510         


Gly Ser Asp Val Ala Leu Arg Glu Leu Met Lys Leu Ala Pro Arg Tyr 
        515                 520                 525             


Lys Leu Gly Val His Gly Tyr Ala Phe Leu Asn Thr Asn Asn Gly Tyr 
    530                 535                 540                 


Ile Leu Ser His Pro Asp Leu Arg Pro Leu Tyr Arg Glu Gly Lys Lys 
545                 550                 555                 560 


Leu Lys Pro Lys Pro Asn Tyr Asn Ser Val Asp Leu Ser Glu Val Glu 
                565                 570                 575     


Trp Glu Asp Gln Ala Glu Ser Leu Arg Thr Ala Met Ile Asn Arg Glu 
            580                 585                 590         


Thr Gly Thr Leu Ser Met Asp Val Lys Val Pro Met Asp Lys Gly Lys 
        595                 600                 605             


Arg Val Leu Phe Leu Thr Asn Asp Tyr Phe Phe Thr Asp Ile Ser Asp 
    610                 615                 620                 


Thr Pro Phe Ser Leu Gly Val Val Leu Ser Arg Gly His Gly Glu Tyr 
625                 630                 635                 640 


Ile Leu Leu Gly Asn Thr Ser Val Glu Glu Gly Leu His Asp Leu Leu 
                645                 650                 655     


His Pro Asp Leu Ala Leu Ala Gly Asp Trp Ile Tyr Cys Ile Thr Asp 
            660                 665                 670         


Ile Asp Pro Asp His Arg Lys Leu Ser Gln Leu Glu Ala Met Ile Arg 
        675                 680                 685             


Phe Leu Ala Arg Lys Asp Pro Asp Leu Glu Cys Asp Glu Glu Leu Val 
    690                 695                 700                 


Arg Glu Val Leu Phe Asp Ala Val Val Thr Ala Pro Met Glu Ala Tyr 
705                 710                 715                 720 


Trp Thr Ala Leu Ala Leu Asn Met Ser Glu Glu Ser Glu His Val Val 
                725                 730                 735     


Asp Met Ala Phe Leu Gly Thr Arg Ala Gly Leu Leu Arg Ser Ser Leu 
            740                 745                 750         


Phe Val Gly Ser Glu Lys Val Ser Asp Arg Lys Phe Leu Thr Pro Glu 
        755                 760                 765             


Asp Glu Ala Ser Val Phe Thr Leu Asp Arg Phe Pro Leu Trp Tyr Arg 
    770                 775                 780                 


Gln Ala Ser Glu His Pro Ala Gly Ser Phe Val Phe Asn Leu Arg Trp 
785                 790                 795                 800 


Ala Glu Gly Pro Glu Ser Ala Gly Glu Pro Met Val Val Thr Ala Ser 
                805                 810                 815     


Thr Ala Val Ala Val Thr Val Asp Lys Arg Thr Ala Ile Ala Ala Ala 
            820                 825                 830         


Ala Gly Val Gln Met Lys Leu Glu Phe Leu Gln Arg Lys Phe Trp Ala 
        835                 840                 845             


Ala Thr Arg Gln Cys Ser Thr Val Asp Gly Pro Cys Thr Gln Ser Cys 
    850                 855                 860                 


Glu Asp Ser Asp Leu Asp Cys Phe Val Ile Asp Asn Asn Gly Phe Ile 
865                 870                 875                 880 


Leu Ile Ser Lys Arg Ser Arg Glu Thr Gly Arg Phe Leu Gly Glu Val 
                885                 890                 895     


Asp Gly Ala Val Leu Thr Gln Leu Leu Ser Met Gly Val Phe Ser Gln 
            900                 905                 910         


Val Thr Met Tyr Asp Tyr Gln Ala Met Cys Lys Pro Ser Ser His His 
        915                 920                 925             


His Ser Ala Ala Gln Pro Leu Val Ser Pro Ile Ser Ala Phe Leu Thr 
    930                 935                 940                 


Ala Thr Arg Trp Leu Leu Gln Glu Leu Val Leu Phe Leu Leu Glu Trp 
945                 950                 955                 960 


Ser Val Trp Gly Ser Trp Tyr Asp Arg Gly Ala Glu Ala Lys Ser Val 
                965                 970                 975     


Phe His His Ser His Lys His Lys Lys Gln Asp Pro Leu Gln Pro Cys 
            980                 985                 990         


Asp Thr Glu Tyr Pro Val Phe Val  Tyr Gln Pro Ala Ile  Arg Glu Ala 
        995                 1000                 1005             


Asn Gly  Ile Val Glu Cys Glu  Pro Cys Gln Lys Val  Phe Val Val 
    1010                 1015                 1020             


Gln Gln  Ile Pro Asn Ser Asn  Leu Leu Leu Leu Val  Thr Asp Pro 
    1025                 1030                 1035             


Thr Cys  Asp Cys Ser Ile Phe  Pro Pro Val Leu Gln  Glu Ala Thr 
    1040                 1045                 1050             


Glu Val  Lys Tyr Asn Ala Ser  Val Lys Cys Asp Arg  Met Arg Ser 
    1055                 1060                 1065             


Gln Lys  Leu Arg Arg Arg Pro  Asp Ser Cys His Ala  Phe His Pro 
    1070                 1075                 1080             


Glu Glu  Asn Ala Gln Asp Cys  Gly Gly Ala Ser Asp  Thr 
    1085                 1090                 1095     


<210>  2590
<211>  78
<212>  PRT
<213>  Homo Sapiens

<400>  2590

His Arg Ser Val Ser Gly Leu Lys Gln Thr Leu Leu Ala Glu Ser Glu 
1               5                   10                  15      


Ala Leu Thr Ser Tyr Ser His Arg Val Phe Ser Ala Trp Asp Phe Gly 
            20                  25                  30          


Leu Cys Gly Asp Val His Val Arg Leu Arg Gln Arg Ile Ile Leu Tyr 
        35                  40                  45              


Glu Leu Lys Val Glu Leu Glu Glu Thr Val Val Arg Arg Gln Ala Ala 
    50                  55                  60                  


Val Arg Thr Leu Gly Gln Gln Ala Arg Val Trp Leu Val Arg 
65                  70                  75              


<210>  2591
<211>  1009
<212>  PRT
<213>  Homo Sapiens

<400>  2591

Ser Thr Gln Gly Phe His Val Asp His Thr Ala Glu Leu Arg Gly Ile 
1               5                   10                  15      


Arg Trp Thr Ser Ser Leu Arg Arg Glu Thr Ser Asp Tyr His Arg Thr 
            20                  25                  30          


Leu Thr Pro Thr Leu Glu Ala Leu Leu His Phe Leu Leu Arg Pro Leu 
        35                  40                  45              


Gln Thr Leu Ser Leu Gly Leu Glu Glu Glu Leu Leu Gln Arg Gly Ile 
    50                  55                  60                  


Arg Ala Arg Leu Arg Glu His Gly Ile Ser Leu Ala Ala Tyr Gly Thr 
65                  70                  75                  80  


Ile Val Ser Ala Glu Leu Thr Gly Arg His Lys Gly Pro Leu Ala Glu 
                85                  90                  95      


Arg Asp Phe Lys Ser Gly Arg Cys Pro Gly Asn Ser Phe Ser Cys Gly 
            100                 105                 110         


Asn Ser Gln Cys Val Thr Lys Val Asn Pro Glu Cys Asp Asp Gln Glu 
        115                 120                 125             


Asp Cys Ser Asp Gly Ser Asp Glu Ala His Cys Glu Cys Gly Leu Gln 
    130                 135                 140                 


Pro Ala Trp Arg Met Ala Gly Arg Ile Val Gly Gly Met Glu Ala Ser 
145                 150                 155                 160 


Pro Gly Glu Phe Pro Trp Gln Ala Ser Leu Arg Glu Asn Lys Glu His 
                165                 170                 175     


Phe Cys Gly Ala Ala Ile Ile Asn Ala Arg Trp Leu Val Ser Ala Ala 
            180                 185                 190         


His Cys Phe Asn Glu Phe Gln Asp Pro Thr Lys Trp Val Ala Tyr Val 
        195                 200                 205             


Gly Ala Thr Tyr Leu Ser Gly Ser Glu Ala Ser Thr Val Arg Ala Gln 
    210                 215                 220                 


Val Val Gln Ile Val Lys His Pro Leu Tyr Asn Ala Asp Thr Ala Asp 
225                 230                 235                 240 


Phe Asp Val Ala Val Leu Glu Leu Thr Ser Pro Leu Pro Phe Gly Arg 
                245                 250                 255     


His Ile Gln Pro Val Cys Leu Pro Ala Ala Thr His Ile Phe Pro Pro 
            260                 265                 270         


Ser Lys Lys Cys Leu Ile Ser Gly Trp Gly Tyr Leu Lys Glu Asp Phe 
        275                 280                 285             


Leu Val Lys Pro Glu Val Leu Gln Lys Ala Thr Val Glu Leu Leu Asp 
    290                 295                 300                 


Gln Ala Leu Cys Ala Ser Leu Tyr Gly His Ser Leu Thr Asp Arg Met 
305                 310                 315                 320 


Val Cys Ala Gly Tyr Leu Asp Gly Lys Val Asp Ser Cys Gln Gly Asp 
                325                 330                 335     


Ser Gly Gly Pro Leu Val Cys Glu Glu Pro Ser Gly Arg Phe Phe Leu 
            340                 345                 350         


Ala Gly Ile Val Ser Trp Gly Ile Gly Cys Ala Glu Ala Arg Arg Pro 
        355                 360                 365             


Gly Val Tyr Ala Arg Val Thr Arg Leu Arg Asp Trp Ile Leu Glu Ala 
    370                 375                 380                 


Thr Thr Lys Ala Ser Met Pro Leu Ala Pro Thr Met Ala Pro Ala Pro 
385                 390                 395                 400 


Ala Ala Pro Ser Thr Ala Trp Pro Thr Ser Pro Glu Ser Pro Val Val 
                405                 410                 415     


Ser Thr Pro Thr Lys Ser Met Gln Ala Leu Ser Thr Val Pro Leu Asp 
            420                 425                 430         


Trp Val Thr Val Pro Lys Leu Gln Glu Cys Gly Ala Arg Pro Ala Met 
        435                 440                 445             


Glu Lys Pro Thr Arg Val Val Gly Gly Phe Gly Ala Ala Ser Gly Glu 
    450                 455                 460                 


Val Pro Trp Gln Val Ser Leu Lys Glu Gly Ser Arg His Phe Cys Gly 
465                 470                 475                 480 


Ala Thr Val Val Gly Asp Arg Trp Leu Leu Ser Ala Ala His Cys Phe 
                485                 490                 495     


Asn His Thr Lys Val Glu Gln Val Arg Ala His Leu Gly Thr Ala Ser 
            500                 505                 510         


Leu Leu Gly Leu Gly Gly Ser Pro Val Lys Ile Gly Leu Arg Arg Val 
        515                 520                 525             


Val Leu His Pro Leu Tyr Asn Pro Gly Ile Leu Asp Phe Asp Leu Ala 
    530                 535                 540                 


Val Leu Glu Leu Ala Ser Pro Leu Ala Phe Asn Lys Tyr Ile Gln Pro 
545                 550                 555                 560 


Val Cys Leu Pro Leu Ala Ile Gln Lys Phe Pro Val Gly Arg Lys Cys 
                565                 570                 575     


Met Ile Ser Gly Trp Gly Asn Thr Gln Glu Gly Asn Ala Thr Lys Pro 
            580                 585                 590         


Glu Leu Leu Gln Lys Ala Ser Val Gly Ile Ile Asp Gln Lys Thr Cys 
        595                 600                 605             


Ser Val Leu Tyr Asn Phe Ser Leu Thr Asp Arg Met Ile Cys Ala Gly 
    610                 615                 620                 


Phe Leu Glu Gly Lys Val Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro 
625                 630                 635                 640 


Leu Ala Cys Glu Glu Ala Pro Gly Val Phe Tyr Leu Ala Gly Ile Val 
                645                 650                 655     


Ser Trp Gly Ile Gly Cys Ala Gln Val Lys Lys Pro Gly Val Tyr Thr 
            660                 665                 670         


Arg Ile Thr Arg Leu Lys Gly Trp Ile Leu Glu Ile Met Ser Ser Gln 
        675                 680                 685             


Pro Leu Pro Met Ser Pro Pro Ser Thr Thr Arg Met Leu Ala Thr Thr 
    690                 695                 700                 


Ser Pro Arg Thr Thr Ala Gly Leu Thr Val Pro Gly Ala Thr Pro Ser 
705                 710                 715                 720 


Arg Pro Thr Pro Gly Ala Ala Ser Arg Val Thr Gly Gln Pro Ala Asn 
                725                 730                 735     


Ser Thr Leu Ser Ala Val Ser Thr Thr Ala Arg Gly Gln Thr Pro Phe 
            740                 745                 750         


Pro Asp Ala Pro Glu Ala Thr Thr His Thr Gln Leu Pro Asp Cys Gly 
        755                 760                 765             


Leu Ala Pro Ala Ala Leu Thr Arg Ile Val Gly Gly Ser Ala Ala Gly 
    770                 775                 780                 


Arg Gly Glu Trp Pro Trp Gln Val Ser Leu Trp Leu Arg Arg Arg Glu 
785                 790                 795                 800 


His Arg Cys Gly Ala Val Leu Val Ala Glu Arg Trp Leu Leu Ser Ala 
                805                 810                 815     


Ala His Cys Phe Asp Val Tyr Gly Asp Pro Lys Gln Trp Ala Ala Phe 
            820                 825                 830         


Leu Gly Thr Pro Phe Leu Ser Gly Ala Glu Gly Gln Leu Glu Arg Val 
        835                 840                 845             


Ala Arg Ile Tyr Lys His Pro Phe Tyr Asn Leu Tyr Thr Leu Asp Tyr 
    850                 855                 860                 


Asp Val Ala Leu Leu Glu Leu Ala Gly Pro Val Arg Arg Ser Arg Leu 
865                 870                 875                 880 


Val Arg Pro Ile Cys Leu Pro Glu Pro Ala Pro Arg Pro Pro Asp Gly 
                885                 890                 895     


Thr Arg Cys Val Ile Thr Gly Trp Gly Ser Val Arg Glu Gly Gly Ser 
            900                 905                 910         


Met Ala Arg Gln Leu Gln Lys Ala Ala Val Arg Leu Leu Ser Glu Gln 
        915                 920                 925             


Thr Cys Arg Arg Phe Tyr Pro Val Gln Ile Ser Ser Arg Met Leu Cys 
    930                 935                 940                 


Ala Gly Phe Pro Gln Gly Gly Val Asp Ser Cys Ser Gly Asp Ala Gly 
945                 950                 955                 960 


Gly Pro Leu Ala Cys Arg Glu Pro Ser Gly Arg Trp Val Leu Thr Gly 
                965                 970                 975     


Val Thr Ser Trp Gly Tyr Gly Cys Gly Arg Pro His Phe Pro Gly Val 
            980                 985                 990         


Tyr Thr Arg Val Ala Ala Val Arg  Gly Trp Ile Gly Gln  His Ile Gln 
        995                 1000                 1005             


Glu 
    


<210>  2592
<211>  424
<212>  PRT
<213>  Homo Sapiens

<400>  2592

His Pro Asp Arg Ile Ile Phe Pro Asn His Ala Cys Glu Asp Pro Pro 
1               5                   10                  15      


Ala Val Leu Leu Glu Val Gln Gly Thr Leu Gln Arg Pro Leu Val Arg 
            20                  25                  30          


Asp Ser Arg Thr Ser Pro Ala Asn Cys Thr Trp Leu Ile Leu Gly Ser 
        35                  40                  45              


Lys Glu Gln Thr Val Thr Ile Arg Phe Gln Lys Leu His Leu Ala Cys 
    50                  55                  60                  


Gly Ser Glu Arg Leu Thr Leu Arg Ser Pro Leu Gln Pro Leu Ile Ser 
65                  70                  75                  80  


Leu Cys Glu Ala Pro Pro Ser Pro Leu Gln Leu Pro Gly Gly Asn Val 
                85                  90                  95      


Thr Ile Thr Tyr Ser Tyr Ala Gly Ala Arg Ala Pro Met Gly Gln Gly 
            100                 105                 110         


Phe Leu Leu Ser Tyr Ser Gln Asp Trp Leu Met Cys Leu Gln Glu Glu 
        115                 120                 125             


Phe Gln Cys Leu Asn His Arg Cys Val Ser Ala Val Gln Arg Cys Asp 
    130                 135                 140                 


Gly Val Asp Ala Cys Gly Asp Gly Ser Asp Glu Ala Gly Cys Ser Ser 
145                 150                 155                 160 


Asp Pro Phe Pro Gly Leu Thr Pro Arg Pro Val Pro Ser Leu Pro Cys 
                165                 170                 175     


Asn Val Thr Leu Glu Asp Phe Tyr Gly Val Phe Ser Ser Pro Gly Tyr 
            180                 185                 190         


Thr His Leu Ala Ser Val Ser His Pro Gln Ser Cys His Trp Leu Leu 
        195                 200                 205             


Asp Pro His Asp Gly Arg Arg Leu Ala Val Arg Phe Thr Ala Leu Asp 
    210                 215                 220                 


Leu Gly Phe Gly Asp Ala Val His Val Tyr Asp Gly Pro Gly Pro Pro 
225                 230                 235                 240 


Glu Ser Ser Arg Leu Leu Arg Ser Leu Thr His Phe Ser Asn Gly Lys 
                245                 250                 255     


Ala Val Thr Val Glu Thr Leu Ser Gly Gln Ala Val Val Ser Tyr His 
            260                 265                 270         


Thr Val Ala Trp Ser Asn Gly Arg Gly Phe Asn Ala Thr Tyr His Val 
        275                 280                 285             


Arg Gly Tyr Cys Leu Pro Trp Asp Arg Pro Cys Gly Leu Gly Ser Gly 
    290                 295                 300                 


Leu Gly Ala Gly Glu Gly Leu Gly Glu Arg Cys Tyr Ser Glu Ala Gln 
305                 310                 315                 320 


Arg Cys Asp Gly Ser Trp Asp Cys Ala Asp Gly Thr Asp Glu Glu Asp 
                325                 330                 335     


Cys Pro Gly Cys Pro Pro Gly His Phe Pro Cys Gly Ala Ala Gly Thr 
            340                 345                 350         


Ser Gly Ala Thr Ala Cys Tyr Leu Pro Ala Asp Arg Cys Asn Tyr Gln 
        355                 360                 365             


Thr Phe Cys Ala Asp Gly Ala Asp Glu Arg Arg Cys Arg His Cys Gln 
    370                 375                 380                 


Pro Gly Asn Phe Arg Cys Arg Asp Glu Lys Cys Val Tyr Glu Thr Trp 
385                 390                 395                 400 


Val Cys Asp Gly Gln Pro Asp Cys Ala Asp Gly Ser Asp Glu Trp Asp 
                405                 410                 415     


Cys Ser Tyr Val Leu Pro Arg Lys 
            420                 


<210>  2593
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  2593

Lys Ile Tyr Thr Arg Cys Lys Leu Ala Lys Ile Phe Ser Arg Ala Gly 
1               5                   10                  15      


Leu Asp Asn Tyr Trp Gly Phe Ser Leu Gly Asn Trp Ile Cys Met Ala 
            20                  25                  30          


Tyr Tyr Glu Ser Gly Tyr Asn Thr Thr Ala Gln Thr Val Leu Asp Asp 
        35                  40                  45              


Gly Ser Ile Asp Tyr Gly Ile Phe Gln Ile Asn Ser Phe Ala Trp Cys 
    50                  55                  60                  


Arg Arg Gly Lys Leu Lys Glu Asn Asn His Cys His Val Ala Cys Ser 
65                  70                  75                  80  


Ala Leu Val Thr Asp Asp Leu Thr Asp Ala Ile Ile Cys Ala Lys Lys 
                85                  90                  95      


Ile Val Lys Glu Thr Gln Gly Met Asn Tyr Trp Gln Gly Trp Lys Lys 
            100                 105                 110         


His Cys Glu Gly Arg Asp Leu Ser Asp Trp Lys Lys Asp Cys Glu Val 
        115                 120                 125             


Ser 
    


<210>  2594
<211>  267
<212>  PRT
<213>  Homo Sapiens

<400>  2594

Gly Met Ala Ala Pro Arg Leu Pro Ser Pro Leu Leu Ser Glu Glu Gly 
1               5                   10                  15      


Gly Glu Asn Pro Glu Ala Ser Pro Ala Pro Gly Pro Glu Ala Gly Pro 
            20                  25                  30          


Pro Leu Asn Leu Phe Thr Ser Phe Pro Gly Asp Ser Leu Leu Cys Gly 
        35                  40                  45              


Arg Thr Pro Leu Arg Ile Val Gly Gly Val Asp Ala Glu Glu Gly Arg 
    50                  55                  60                  


Trp Pro Trp Gln Val Ser Val Arg Thr Lys Gly Arg His Ile Cys Gly 
65                  70                  75                  80  


Gly Thr Leu Val Thr Ala Thr Trp Val Leu Thr Ala Gly His Cys Ile 
                85                  90                  95      


Ser Ser Arg Phe His Tyr Ser Val Lys Met Gly Asp Arg Ser Val Tyr 
            100                 105                 110         


Asn Glu Asn Thr Ser Val Val Val Ser Val Gln Arg Ala Phe Val His 
        115                 120                 125             


Pro Lys Phe Ser Thr Val Thr Thr Ile Arg Asn Asp Leu Ala Leu Leu 
    130                 135                 140                 


Gln Leu Gln His Pro Val Asn Phe Thr Ser Asn Ile Gln Pro Ile Cys 
145                 150                 155                 160 


Ile Pro Gln Glu Asn Phe Gln Val Glu Gly Arg Thr Arg Cys Trp Val 
                165                 170                 175     


Thr Gly Trp Gly Lys Thr Pro Glu Arg Glu Lys Leu Ala Ser Glu Ile 
            180                 185                 190         


Leu Gln Asp Val Asp Gln Tyr Ile Met Cys Tyr Glu Glu Cys Asn Lys 
        195                 200                 205             


Ile Ile Gln Lys Ala Leu Ser Ser Thr Lys Asp Val Ile Ile Lys Gly 
    210                 215                 220                 


Met Val Cys Gly Tyr Lys Glu Gln Gly Lys Asp Ser Cys Gln Gly Asp 
225                 230                 235                 240 


Ser Gly Gly Arg Leu Ala Cys Glu Tyr Asn Asp Thr Trp Val Gln Val 
                245                 250                 255     


Gly Ile Val Ser Trp Gly Ile Gly Cys Gly Arg 
            260                 265         


<210>  2595
<211>  139
<212>  PRT
<213>  Homo Sapiens

<400>  2595

Ala Leu Gln Pro Pro Thr Ala Thr Val Leu Val Gln Gln Gly Thr Cys 
1               5                   10                  15      


Glu Val Ile Ala Ala His Arg Cys Cys Asn Arg Asn Arg Ile Glu Glu 
            20                  25                  30          


Arg Ser Gln Thr Val Lys Cys Ser Cys Phe Ser Gly Gln Val Ala Gly 
        35                  40                  45              


Thr Thr Arg Ala Lys Pro Ser Cys Val Asp Asp Leu Leu Leu Ala Ala 
    50                  55                  60                  


His Cys Ala Arg Arg Asp Pro Arg Ala Ala Leu Arg Leu Leu Leu Pro 
65                  70                  75                  80  


Gln Pro Pro Ser Ser Cys Arg Asp Gly Gly Val Arg Trp Ser Pro Ala 
                85                  90                  95      


Cys Arg Gly Arg Ser Val Arg Cys Ser Arg Thr Cys Arg Asp Gly Ala 
            100                 105                 110         


Ala Ala Val Asp Thr Lys Ser Lys Pro Pro Arg Ser His Asp Ser Ser 
        115                 120                 125             


Trp Gly Ser Arg Pro Gly Gln Glu Arg Leu Asp 
    130                 135                 


<210>  2596
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  2596

Met Leu Leu Cys His Gly Ser Leu Gln His Thr Phe Gln Gln His His 
1               5                   10                  15      


Leu His Arg Pro Glu Gly Gly Thr Cys Glu Val Ile Ala Ala His Arg 
            20                  25                  30          


Cys Cys Asn Lys Asn Arg Ile Glu Glu Arg Ser Gln Thr Val Lys Cys 
        35                  40                  45              


Ser Cys Leu Pro Gly Lys Val Ala Gly Thr Thr Arg Asn Arg Pro Ser 
    50                  55                  60                  


Cys Val Asp Ala Ser Ile Val Ile Gly Lys Trp Trp Cys Glu Met Glu 
65                  70                  75                  80  


Pro Cys Leu Glu Gly Glu Glu Cys Lys Thr Leu Pro Asp Asn Ser Gly 
                85                  90                  95      


Trp Met Cys Ala Thr Gly Asn Lys Ile Lys Thr Thr Arg Ile His Pro 
            100                 105                 110         


Arg Thr 
        


<210>  2597
<211>  178
<212>  PRT
<213>  Homo Sapiens

<400>  2597

Gln Thr Asp Gly Arg Asn Gly Tyr Thr Ala Val Ile Glu Val Thr Ser 
1               5                   10                  15      


Gly Gly Pro Trp Gly Asp Trp Ala Trp Pro Glu Met Cys Pro Asp Gly 
            20                  25                  30          


Phe Phe Ala Ser Gly Phe Ser Leu Lys Val Glu Pro Pro Gln Gly Ile 
        35                  40                  45              


Pro Gly Asp Asp Thr Ala Leu Asn Gly Ile Arg Leu His Cys Ala Arg 
    50                  55                  60                  


Gly Asn Val Leu Gly Asn Thr His Val Val Glu Ser Gln Ser Gly Ser 
65                  70                  75                  80  


Trp Gly Glu Trp Ser Glu Pro Leu Trp Cys Arg Gly Gly Ala Tyr Leu 
                85                  90                  95      


Val Ala Phe Ser Leu Arg Val Glu Ala Pro Thr Thr Leu Gly Asp Asn 
            100                 105                 110         


Thr Ala Ala Asn Asn Val Arg Phe Arg Cys Ser Asp Gly Glu Glu Leu 
        115                 120                 125             


Gln Gly Pro Gly Leu Ser Trp Gly Asp Phe Gly Asp Trp Ser Asp His 
    130                 135                 140                 


Cys Pro Lys Gly Ala Cys Gly Leu Gln Thr Lys Ile Gln Gly Pro Arg 
145                 150                 155                 160 


Gly Leu Gly Asp Asp Thr Ala Leu Asn Asp Ala Arg Leu Phe Cys Cys 
                165                 170                 175     


Arg Ser 
        


<210>  2598
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  2598

Lys Lys Met Ala Lys Asn Ser Arg Thr Ser Leu Ala Ser Ala Ser Asn 
1               5                   10                  15      


Glu Asn Tyr Thr Phe Cys Trp Arg Val Phe Cys Ala Trp Asp Tyr Leu 
            20                  25                  30          


Ile Gly Asn Pro Glu Ala Ala Glu Ser Lys Thr Ala Ala Ile Val Asn 
        35                  40                  45              


Ser Ile Arg Glu Ala Ile Leu Glu Glu Gln Glu Lys Lys Lys Ser Lys 
    50                  55                  60                  


Asn Leu Ala Val Thr Ile Cys Leu Arg 
65                  70              


<210>  2599
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  2599

Glu Ser Leu Val Lys Phe Phe Ile Pro Gln Arg Arg Lys Ser Val Ala 
1               5                   10                  15      


Gly Glu Ile Val Leu Ile Thr Gly Ala Gly His Gly Ile Gly Arg Gln 
            20                  25                  30          


Thr Thr Tyr Glu Phe Ala Lys Arg Gln Ser Ile Leu Val Leu Trp Asp 
        35                  40                  45              


Ile Asn Lys Arg Gly Val Glu Glu Thr Ala Ala Glu Cys Arg Lys Leu 
    50                  55                  60                  


Gly Val Thr Ala His Ala Tyr Val Val Asp Cys Ser Asn Arg Glu Glu 
65                  70                  75                  80  


Ile Tyr Arg Ser Leu Asn Gln Val Lys Lys Glu Val Gly Asp Val Thr 
                85                  90                  95      


Ile Val Val Asn Asn Ala Gly Thr Val Tyr Pro Ala Asp Leu Leu Ser 
            100                 105                 110         


Thr Lys Asp Glu Glu Ile Thr Lys Thr Phe Glu Val Asn Ile Leu Gly 
        115                 120                 125             


His Phe Trp Ile Thr Lys Ala Leu Leu Pro Ser Met Met Glu Arg Asn 
    130                 135                 140                 


His Gly His Ile Val Thr Val Ala Ser Val Cys Gly His Glu Gly Ile 
145                 150                 155                 160 


Pro Tyr Leu Ile Pro Tyr Cys Ser Ser Lys Phe Ala Ala Val Gly Phe 
                165                 170                 175     


His Arg Gly Leu Thr Ser Glu Leu Gln Ala Leu Gly Lys Thr Gly Ile 
            180                 185                 190         


Lys Thr Ser Cys Leu Cys Pro Val Phe Val Asn Thr Gly Phe Thr Lys 
        195                 200                 205             


Asn Pro Ser Thr Arg Leu Trp Pro Val Leu Glu Thr Asp Glu Val Val 
    210                 215                 220                 


Arg Ser Leu Ile Asp Gly Ile Leu Thr Asn Lys Lys Met Ile Phe Val 
225                 230                 235                 240 


Pro Ser Tyr Ile Asn Ile Phe Leu Arg Leu Gln Lys Phe Leu Pro Glu 
                245                 250                 255     


Arg Ala Ser Ala Ile Leu Asn Arg Met Gln Asn Ile Gln Phe Glu Ala 
            260                 265                 270         


Val Val Gly His Lys Ile Lys Met Lys 
        275                 280     


<210>  2600
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  2600

Gly Gly Ser Lys Cys Val Ser Asn Thr Pro Gly Tyr Cys Arg Thr Cys 
1               5                   10                  15      


Cys His Trp Gly Glu Thr Ala Leu Phe Met Cys Asn Ala Ser Arg Lys 
            20                  25                  30          


Cys Cys Ile Ser Tyr Ser Phe Leu Pro Lys Pro Asp Leu Pro Gln Leu 
        35                  40                  45              


Ile Gly Asn His Trp Gln Ser Arg Arg Arg Asn Thr Gln Arg Lys Asp 
    50                  55                  60                  


Lys Lys Gln Gln Thr Thr Val Thr Ser 
65                  70              


<210>  2601
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  2601

Ser Tyr Pro Phe Ser His Ser Met Lys Pro His Leu His Pro Arg Leu 
1               5                   10                  15      


Tyr His Gly Cys Tyr Gly Asp Ile Met Thr Met Lys Thr Ser Gly Ala 
            20                  25                  30          


Thr Cys Asp Ala Asn Ser Val Met Asn Cys Gly Ile Arg Gly Ser Glu 
        35                  40                  45              


Met Phe Ala Glu Met Asp Leu Arg Ala Ile Lys Pro Tyr Gln Thr Leu 
    50                  55                  60                  


Ile Lys Glu Val Gly Gln Arg His Cys Val Asp Pro Ala Val Ile Ala 
65                  70                  75                  80  


Ala Ile Ile Ser Arg Glu Ser His Gly Gly Ser Val Leu Gln Asp Gly 
                85                  90                  95      


Trp Asp His Arg Gly Leu Lys Phe Gly Leu Met Gln Leu Asp Lys Gln 
            100                 105                 110         


Thr Tyr His Pro Val Gly Ala Trp Asp Ser Lys Glu His Leu Ser Gln 
        115                 120                 125             


Ala Thr Gly Ile Leu Thr Glu Arg Ile Lys Ala Ile Gln Lys Lys Phe 
    130                 135                 140                 


Pro Thr Trp Ser Val Ala Gln His Leu Lys Gly Gly Leu Ser Ala Phe 
145                 150                 155                 160 


Lys Ser Gly Ile Glu Ala Ile Ala Thr Pro Ser Asp Ile Asp Asn Asp 
                165                 170                 175     


Phe Val Asn Asp Ile Ile Ala Arg Ala Lys Phe Tyr Lys Arg Gln Ser 
            180                 185                 190         


Phe 
    


<210>  2602
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2602

Leu Ala Ser Gly Arg Leu Pro Leu Ala Val His Ser Ala Gln His Gly 
1               5                   10                  15      


Pro Gly Ser Gly Ala Pro Trp Leu Arg Ile Ala Arg Arg Ala Leu Arg 
            20                  25                  30          


Phe Val Leu Ser Lys His Trp Gly Asp Asp Cys Tyr Leu Thr Asn Arg 
        35                  40                  45              


Leu Trp Gln Asp Leu Lys Pro Pro Ser His Val Glu Asn Gly Gln Glu 
    50                  55                  60                  


Leu Arg Leu Ala Pro Pro Val Gln Trp Ala Leu Gln Val Gln Gly Asn 
65                  70                  75                  80  


Gln Leu Gln Thr Ala Val Leu Cys Leu Arg Met Ala Pro Pro Glu Pro 
                85                  90                  95      


Ala Gly Ser Arg Gln Arg Ile 
            100             


<210>  2603
<211>  378
<212>  PRT
<213>  Homo Sapiens

<400>  2603

Leu Ala Val Glu Lys Thr Tyr Tyr Tyr Gln Gly Asp Phe His Ile Ser 
1               5                   10                  15      


Gly Val Thr Tyr Asn Asp Asn Cys Glu Asn Ala Ala Ser Gln Ala Ser 
            20                  25                  30          


Thr Asn Leu Ser Lys Asp Ile Glu Thr Lys Met Leu Asn Ala Phe Gln 
        35                  40                  45              


Asn Ser Ser Ile Tyr Lys Glu Tyr Val Lys Ser Glu Val Ile Lys Leu 
    50                  55                  60                  


Leu Pro Asn Ala Asn Gly Ser Asn Val Gln Leu Gln Leu Lys Phe Lys 
65                  70                  75                  80  


Phe Pro Pro Ala Glu Gly Val Ser Met Arg Thr Lys Ile Lys Ala Lys 
                85                  90                  95      


Leu His Gln Met Leu Lys Asn Asn Met Ala Ser Trp Asn Ala Val Pro 
            100                 105                 110         


Ala Ser Ile Lys Leu Met Glu Ile Ser Lys Ala Ala Ser Glu Met Leu 
        115                 120                 125             


Thr Asn Asn Cys Cys Gly Arg Gln Val Ala Asn Ser Ile Ile Thr Gly 
    130                 135                 140                 


Asn Lys Ile Val Asn Gly Lys Ser Ser Leu Glu Gly Ala Trp Pro Trp 
145                 150                 155                 160 


Gln Ala Ser Met Gln Trp Lys Gly Arg His Tyr Cys Gly Ala Ser Leu 
                165                 170                 175     


Ile Ser Ser Arg Trp Leu Leu Ser Ala Ala His Cys Phe Ala Lys Lys 
            180                 185                 190         


Asn Asn Ser Lys Asp Trp Thr Val Asn Phe Gly Val Val Val Asn Lys 
        195                 200                 205             


Pro Tyr Met Thr Arg Lys Val Gln Asn Ile Ile Phe His Glu Asn Tyr 
    210                 215                 220                 


Ser Ser Pro Gly Leu His Asp Asp Ile Ala Leu Val Gln Leu Ala Glu 
225                 230                 235                 240 


Glu Val Ser Phe Thr Glu Tyr Ile Arg Lys Ile Cys Leu Pro Glu Ala 
                245                 250                 255     


Lys Met Lys Leu Ser Glu Asn Asp Asn Val Val Val Thr Gly Trp Gly 
            260                 265                 270         


Thr Leu Tyr Met Asn Gly Ser Phe Pro Val Ile Leu Gln Glu Ala Phe 
        275                 280                 285             


Leu Lys Ile Ile Asp Asn Lys Ile Cys Asn Ala Ser Tyr Ala Tyr Ser 
    290                 295                 300                 


Gly Phe Val Thr Asp Ser Met Leu Cys Ala Gly Phe Met Ser Gly Glu 
305                 310                 315                 320 


Ala Asp Ala Cys Gln Asn Asp Ser Gly Gly Pro Leu Ala Tyr Pro Asp 
                325                 330                 335     


Ser Arg Asn Ile Trp His Leu Val Gly Ile Val Ser Trp Gly Asp Gly 
            340                 345                 350         


Cys Gly Lys Lys Asn Lys Pro Gly Val Tyr Thr Arg Val Thr Ser Tyr 
        355                 360                 365             


Arg Asn Trp Ile Thr Ser Lys Thr Gly Leu 
    370                 375             


<210>  2604
<211>  327
<212>  PRT
<213>  Homo Sapiens

<400>  2604

Thr Arg Gln Asp Tyr Glu Glu Leu Glu Lys Gln Leu Lys Glu Val Phe 
1               5                   10                  15      


Lys Glu Arg Ser Thr Ile Leu Arg Gln Leu Thr Lys Thr Ser Arg Glu 
            20                  25                  30          


Leu Asp Gly Ile Lys Val Asn Leu Gln Ser Leu Lys Asn Asp Glu Gln 
        35                  40                  45              


Ser Ala Lys Thr Asp Val Gln Lys Leu Leu Glu Leu Gly Gln Lys Gln 
    50                  55                  60                  


Arg Glu Glu Met Lys Ser Leu Gln Glu Ala Leu Gln Asn Gln Leu Lys 
65                  70                  75                  80  


Glu Thr Ser Glu Lys Ala Glu Lys His Gln Ala Thr Ile Asn Phe Leu 
                85                  90                  95      


Lys Thr Glu Val Glu Arg Lys Ser Lys Met Ile Arg Asp Leu Gln Asn 
            100                 105                 110         


Glu Asn Lys Ser Leu Lys Asn Lys Leu Leu Ser Gly Asn Lys Leu Cys 
        115                 120                 125             


Gly Ile His Ala Glu Glu Ser Lys Lys Ile Gln Ala Gln Leu Lys Glu 
    130                 135                 140                 


Leu Arg Tyr Gly Lys Lys Asp Leu Leu Phe Lys Ala Gln Gln Leu Thr 
145                 150                 155                 160 


Asp Leu Glu Gln Lys Leu Ala Val Ala Lys Asn Glu Leu Glu Lys Ala 
                165                 170                 175     


Ala Leu Asp Arg Glu Ser Gln Met Lys Ala Met Lys Glu Thr Val Gln 
            180                 185                 190         


Leu Cys Leu Thr Ser Val Phe Arg Asp Gln Pro Pro Pro Pro Leu Ser 
        195                 200                 205             


Leu Ile Thr Ser Asn Pro Thr Arg Met Leu Leu Pro Pro Arg Asn Ile 
    210                 215                 220                 


Ala Ser Lys Leu Pro Asp Ala Ala Ala Lys Ser Lys Pro Gln Gln Ser 
225                 230                 235                 240 


Ala Ser Gly Asn Asn Glu Ser Ser Gln Val Glu Ser Thr Lys Glu Gly 
                245                 250                 255     


Asn Pro Ser Thr Thr Ala Cys Asp Ser Gln Asp Glu Gly Arg Pro Cys 
            260                 265                 270         


Ser Met Lys His Lys Glu Ser Pro Pro Ser Asn Ala Thr Ala Glu Thr 
        275                 280                 285             


Glu Pro Ile Pro Gln Lys Leu Gln Met Pro Pro Cys Ser Glu Cys Glu 
    290                 295                 300                 


Val Lys Lys Ala Pro Glu Lys Pro Leu Thr Ser Phe Glu Gly Met Ala 
305                 310                 315                 320 


Ala Arg Glu Glu Lys Ile Leu 
                325         


<210>  2605
<211>  506
<212>  PRT
<213>  Homo Sapiens

<400>  2605

Ala Ser Gly Ile Tyr Phe Tyr Ser Asn Lys Tyr Leu Asp Pro Asn Asp 
1               5                   10                  15      


Phe Gly Ala Val Arg Val Gly Arg Ala Val Ala Thr Thr Ala Val Ile 
            20                  25                  30          


Ser Tyr Asp Tyr Leu Thr Ser Leu Lys Ser Val Pro Tyr Gly Ser Glu 
        35                  40                  45              


Glu Tyr Leu Gln Leu Arg Ser Lys Val His Leu Arg Ser Ala Arg Arg 
    50                  55                  60                  


Leu Cys Glu Leu Cys Cys Ala Asn Arg Gly Thr Phe Ile Lys Val Gly 
65                  70                  75                  80  


Gln His Leu Gly Ala Leu Asp Tyr Leu Leu Pro Glu Glu Tyr Thr Ser 
                85                  90                  95      


Thr Leu Lys Val Leu His Ser Gln Ala Pro Gln Ser Ser Met Gln Glu 
            100                 105                 110         


Ile Arg Gln Val Ile Arg Glu Asp Leu Gly Lys Glu Ile His Asp Leu 
        115                 120                 125             


Phe Gln Ser Phe Asp Asp Thr Pro Leu Gly Thr Ala Ser Leu Ala Gln 
    130                 135                 140                 


Val His Lys Ala Val Leu His Asp Gly Arg Thr Val Ala Val Lys Val 
145                 150                 155                 160 


Gln His Pro Lys Val Arg Ala Gln Ser Ser Lys Asp Ile Leu Leu Met 
                165                 170                 175     


Glu Val Leu Val Leu Ala Val Lys Gln Leu Phe Pro Glu Phe Glu Phe 
            180                 185                 190         


Met Trp Leu Val Asp Glu Ala Lys Lys Asn Leu Pro Leu Glu Leu Asp 
        195                 200                 205             


Phe Leu Asn Glu Gly Arg Asn Ala Glu Lys Val Ser Gln Met Leu Arg 
    210                 215                 220                 


His Phe Asp Phe Leu Lys Val Pro Arg Ile His Trp Asp Leu Ser Thr 
225                 230                 235                 240 


Glu Arg Val Leu Leu Met Glu Phe Val Asp Gly Gly Gln Val Asn Asp 
                245                 250                 255     


Arg Asp Tyr Met Glu Arg Asn Lys Ile Asp Val Asn Glu Ile Ser Arg 
            260                 265                 270         


His Leu Gly Lys Met Tyr Ser Glu Met Ile Phe Val Asn Gly Phe Val 
        275                 280                 285             


His Cys Asp Pro His Pro Gly Asn Val Leu Val Arg Lys His Pro Gly 
    290                 295                 300                 


Thr Gly Lys Ala Glu Ile Val Leu Leu Asp His Gly Leu Tyr Gln Met 
305                 310                 315                 320 


Leu Thr Glu Glu Phe Arg Leu Asn Tyr Cys His Leu Trp Gln Ser Leu 
                325                 330                 335     


Ile Trp Thr Asp Met Lys Arg Val Lys Glu Tyr Ser Gln Arg Leu Gly 
            340                 345                 350         


Ala Gly Asp Leu Tyr Pro Leu Phe Ala Cys Met Leu Thr Ala Arg Ser 
        355                 360                 365             


Trp Asp Ser Val Asn Arg Gly Ile Ser Gln Ala Pro Val Thr Ala Thr 
    370                 375                 380                 


Glu Asp Leu Glu Ile Arg Asn Asn Ala Ala Asn Tyr Leu Pro Gln Ile 
385                 390                 395                 400 


Ser His Leu Leu Asn His Val Pro Arg Gln Met Leu Leu Ile Leu Lys 
                405                 410                 415     


Thr Asn Asp Leu Leu Arg Gly Ile Glu Ala Ala Leu Gly Thr Arg Ala 
            420                 425                 430         


Ser Ala Ser Ser Phe Leu Asn Met Ser Arg Cys Cys Ile Arg Ala Leu 
        435                 440                 445             


Ala Glu His Lys Lys Lys Asn Thr Cys Ser Phe Phe Arg Arg Thr Gln 
    450                 455                 460                 


Ile Ser Phe Ser Glu Ala Phe Asn Leu Trp Gln Ile Asn Leu His Glu 
465                 470                 475                 480 


Leu Ile Leu Arg Val Lys Gly Leu Lys Leu Ala Asp Arg Val Leu Ala 
                485                 490                 495     


Leu Ile Cys Trp Leu Phe Pro Ala Pro Leu 
            500                 505     


<210>  2606
<211>  747
<212>  PRT
<213>  Homo Sapiens

<400>  2606

Phe Pro Lys Ile Glu Arg Arg Arg Glu Ile Ala His Val His Ala Glu 
1               5                   10                  15      


Lys Gly Gln Ser Asp Lys Met Asn Thr Asp Asp Leu Glu Asn Ser Ser 
            20                  25                  30          


Val Thr Ser Lys Gln Thr Pro Gln Leu Val Val Ser Glu Asp Pro Met 
        35                  40                  45              


Met Met Ser Ala Val Pro Ser Ala Thr Ser Leu Asn Lys Ala Phe Ser 
    50                  55                  60                  


Ile Asn Lys Glu Ile Gln Pro Gly Gln Ala Gly Leu Met Gln Thr Glu 
65                  70                  75                  80  


Arg Pro Gly Val Ser Thr Pro Thr Glu Ser Gly Val Pro Ser Ala Glu 
                85                  90                  95      


Glu Val Phe Gly Ser Ser Gln Pro Glu Arg Ile Ser Pro Glu Ser Gly 
            100                 105                 110         


Leu Ala Lys Ala Met Leu Thr Ile Ala Ile Thr Ala Thr Pro Ser Leu 
        115                 120                 125             


Thr Val Asp Glu Lys Glu Glu Leu Leu Thr Ser Thr Asn Phe Gln Pro 
    130                 135                 140                 


Ile Val Glu Glu Ile Thr Glu Thr Thr Lys Gly Phe Leu Lys Tyr Met 
145                 150                 155                 160 


Asp Asn Gln Ser Phe Ala Thr Glu Ser Gln Glu Gly Val Gly Leu Gly 
                165                 170                 175     


His Ser Pro Ser Ser Tyr Val Asn Thr Lys Glu Met Leu Thr Thr Asn 
            180                 185                 190         


Pro Lys Thr Glu Lys Phe Glu Ala Asp Thr Asp His Arg Thr Thr Ser 
        195                 200                 205             


Phe Pro Gly Ala Glu Ser Thr Ala Gly Ser Glu Pro Gly Ser Leu Thr 
    210                 215                 220                 


Pro Asp Lys Glu Lys Pro Ser Gln Met Thr Ala Asp Asn Thr Gln Ala 
225                 230                 235                 240 


Ala Ala Thr Lys Gln Pro Leu Glu Thr Ser Glu Tyr Thr Leu Ser Val 
                245                 250                 255     


Glu Pro Glu Thr Asp Ser Leu Leu Gly Ala Pro Glu Val Thr Val Ser 
            260                 265                 270         


Val Ser Thr Ala Val Pro Ala Ala Ser Ala Leu Ser Asp Glu Trp Asp 
        275                 280                 285             


Asp Thr Lys Leu Glu Ser Val Ser Arg Ile Arg Thr Pro Lys Leu Gly 
    290                 295                 300                 


Asp Asn Glu Glu Thr Gln Val Arg Thr Glu Met Ser Gln Thr Ala Gln 
305                 310                 315                 320 


Val Ser His Glu Gly Met Glu Gly Gly Gln Pro Trp Thr Glu Ala Ala 
                325                 330                 335     


Gln Val Ala Leu Gly Leu Pro Glu Gly Glu Thr His Thr Gly Thr Ala 
            340                 345                 350         


Leu Leu Ile Ala His Gly Asn Glu Arg Ser Pro Ala Phe Thr Asp Gln 
        355                 360                 365             


Ser Ser Phe Thr Pro Thr Ser Leu Met Glu Asp Met Lys Val Ser Ile 
    370                 375                 380                 


Val Asn Leu Leu Gln Ser Thr Gly Asp Phe Thr Glu Ser Thr Lys Glu 
385                 390                 395                 400 


Asn Asp Ala Leu Phe Phe Leu Glu Thr Thr Val Ser Val Ser Val Tyr 
                405                 410                 415     


Glu Ser Glu Ala Asp Gln Leu Leu Gly Asn Thr Met Lys Asp Ile Ile 
            420                 425                 430         


Thr Gln Glu Met Thr Thr Ala Val Gln Glu Pro Asp Ala Thr Leu Ser 
        435                 440                 445             


Met Val Thr Gln Glu Gln Val Ala Thr Leu Glu Leu Ile Arg Asp Ser 
    450                 455                 460                 


Gly Lys Thr Glu Glu Glu Lys Glu Asp Pro Ser Pro Val Ser Asp Val 
465                 470                 475                 480 


Pro Gly Val Thr Gln Leu Ser Arg Arg Trp Glu Pro Leu Ala Thr Thr 
                485                 490                 495     


Ile Ser Thr Thr Val Val Pro Leu Ser Phe Glu Val Thr Pro Thr Val 
            500                 505                 510         


Glu Glu Gln Met Asp Thr Val Thr Gly Pro Asn Glu Glu Phe Thr Pro 
        515                 520                 525             


Val Leu Gly Ser Pro Val Thr Pro Pro Gly Ile Met Val Gly Glu Pro 
    530                 535                 540                 


Ser Ile Ser Pro Ala Leu Pro Ala Leu Glu Ala Ser Ser Glu Arg Arg 
545                 550                 555                 560 


Thr Val Val Pro Ser Ile Thr Arg Val Asn Thr Ala Ala Ser Tyr Gly 
                565                 570                 575     


Leu Asp Gln Leu Glu Ser Glu Glu Gly Glu Glu Asp Glu Asp Glu Glu 
            580                 585                 590         


Asp Glu Glu Asp Glu Asp Glu Glu Glu Glu Asp Glu Glu Glu Asp Glu 
        595                 600                 605             


Glu Asp Lys Asp Ala Asp Ser Leu Asp Glu Gly Leu Asp Gly Asp Thr 
    610                 615                 620                 


Glu Leu Pro Gly Phe Thr Leu Pro Gly Ile Thr Ser Gln Glu Pro Gly 
625                 630                 635                 640 


Leu Glu Glu Gly Asn Met Asp Leu Leu Glu Gly Ala Thr Tyr Gln Val 
                645                 650                 655     


Pro Asp Ala Leu Glu Trp Glu Gln Gln Asn Gln Gly Leu Val Arg Ser 
            660                 665                 670         


Trp Met Glu Lys Leu Lys Asp Lys Ala Gly Tyr Met Ser Gly Met Leu 
        675                 680                 685             


Val Pro Val Gly Val Gly Ile Ala Gly Ala Leu Phe Ile Leu Gly Ala 
    690                 695                 700                 


Leu Tyr Ser Ile Lys Val Met Asn Arg Arg Arg Arg Asn Gly Phe Lys 
705                 710                 715                 720 


Arg His Lys Arg Lys Gln Arg Glu Phe Asn Ser Met Gln Asp Arg Val 
                725                 730                 735     


Met Leu Leu Ala Asp Ser Ser Glu Asp Glu Phe 
            740                 745         


<210>  2607
<211>  403
<212>  PRT
<213>  Homo Sapiens

<400>  2607

Gln Pro Leu Leu Ala His Gly Asp Lys Ser Leu Gln Gly Pro Gln Pro 
1               5                   10                  15      


Pro Arg His Gln Leu Ser Glu Pro Ala Pro Ala Tyr His Arg Ile Thr 
            20                  25                  30          


Pro Thr Ile Thr Asn Phe Ala Leu Arg Leu Tyr Lys Glu Leu Ala Ala 
        35                  40                  45              


Asp Ala Pro Gly Asn Ile Phe Phe Ser Pro Val Ser Ile Ser Thr Thr 
    50                  55                  60                  


Leu Ala Leu Leu Ser Leu Gly Ala Gln Ala Asn Thr Ser Ala Leu Ile 
65                  70                  75                  80  


Leu Glu Gly Leu Gly Phe Asn Leu Thr Glu Thr Pro Glu Ala Asp Ile 
                85                  90                  95      


His Gln Gly Phe Arg Ser Leu Leu His Thr Leu Ala Leu Pro Ser Pro 
            100                 105                 110         


Lys Leu Glu Leu Lys Val Gly Asn Ser Leu Phe Leu Asp Lys Arg Leu 
        115                 120                 125             


Lys Pro Arg Gln His Tyr Leu Asp Ser Ile Lys Glu Leu Tyr Gly Ala 
    130                 135                 140                 


Phe Ala Phe Ser Ala Asn Phe Thr Asp Ser Val Thr Thr Gly Arg Gln 
145                 150                 155                 160 


Ile Asn Asp Tyr Leu Arg Arg Gln Thr Tyr Gly Gln Val Val Asp Cys 
                165                 170                 175     


Leu Pro Glu Phe Ser Gln Asp Thr Phe Met Val Leu Ala Asn Tyr Ile 
            180                 185                 190         


Phe Phe Lys Ala Lys Trp Lys His Pro Phe Ser Arg Tyr Gln Thr Gln 
        195                 200                 205             


Lys Gln Glu Ser Phe Phe Val Asp Glu Arg Thr Ser Leu Gln Val Pro 
    210                 215                 220                 


Met Met His Gln Lys Glu Met His Arg Phe Leu Tyr Asp Gln Asp Leu 
225                 230                 235                 240 


Ala Cys Thr Val Leu Gln Ile Glu Tyr Arg Gly Asn Ala Leu Ala Leu 
                245                 250                 255     


Leu Val Leu Pro Asp Pro Gly Lys Met Lys Gln Val Glu Ala Ala Leu 
            260                 265                 270         


Gln Pro Gln Thr Leu Arg Lys Trp Gly Gln Leu Leu Leu Pro Ser Leu 
        275                 280                 285             


Leu Asp Leu His Leu Pro Arg Phe Ser Ile Ser Gly Thr Tyr Asn Leu 
    290                 295                 300                 


Glu Asp Ile Leu Pro Gln Ile Gly Leu Thr Asn Ile Leu Asn Leu Glu 
305                 310                 315                 320 


Ala Asp Phe Ser Gly Val Thr Gly Gln Leu Asn Lys Thr Ile Ser Lys 
                325                 330                 335     


Val Ser His Lys Ala Met Val Asp Met Ser Glu Lys Gly Thr Glu Ala 
            340                 345                 350         


Gly Ala Ala Ser Gly Leu Leu Ser Gln Pro Pro Ser Leu Asn Thr Met 
        355                 360                 365             


Ser Asp Pro His Ala His Phe Asn Arg Pro Phe Leu Leu Leu Leu Trp 
    370                 375                 380                 


Glu Val Thr Thr Gln Ser Leu Leu Phe Leu Gly Lys Val Val Asn Pro 
385                 390                 395                 400 


Val Ala Gly 
            


<210>  2608
<211>  246
<212>  PRT
<213>  Homo Sapiens

<400>  2608

Ala Pro Ala Glu Leu Arg Val Arg Val Arg Leu Pro Asp Gly Gln Val 
1               5                   10                  15      


Thr Glu Glu Ser Leu Gln Ala Asp Ser Asp Ala Asp Ser Ile Ser Leu 
            20                  25                  30          


Glu Leu Arg Lys Pro Asp Gly Thr Leu Val Ser Phe Thr Ala Asp Phe 
        35                  40                  45              


Lys Lys Asp Val Lys Val Phe Arg Ala Leu Ile Leu Gly Glu Leu Glu 
    50                  55                  60                  


Lys Gly Gln Ser Gln Phe Gln Ala Leu Cys Phe Val Thr Gln Leu Gln 
65                  70                  75                  80  


His Asn Glu Ile Ile Pro Ser Glu Ala Met Ala Lys Leu Arg Gln Lys 
                85                  90                  95      


Asn Pro Arg Ala Val Arg Gln Ala Glu Glu Val Arg Gly Leu Glu His 
            100                 105                 110         


Leu His Met Asp Val Ala Val Asn Phe Ser Gln Gly Ala Leu Leu Ser 
        115                 120                 125             


Pro His Leu His Asn Val Cys Ala Glu Ala Val Asp Ala Ile Tyr Thr 
    130                 135                 140                 


Arg Gln Glu Asp Val Arg Phe Trp Leu Glu Gln Gly Val Asp Ser Ser 
145                 150                 155                 160 


Val Phe Glu Ala Leu Pro Lys Ala Ser Glu Gln Ala Glu Leu Pro Arg 
                165                 170                 175     


Cys Arg Gln Val Gly Asp His Gly Lys Pro Cys Val Cys Arg Tyr Gly 
            180                 185                 190         


Leu Ser Leu Ala Trp Tyr Pro Cys Met Leu Lys Tyr Cys His Ser Arg 
        195                 200                 205             


Asp Arg Pro Thr Pro Tyr Lys Cys Gly Ile Arg Ser Cys Gln Lys Ser 
    210                 215                 220                 


Tyr Ser Phe Asp Phe Tyr Val Pro Gln Arg Gln Leu Cys Leu Trp Asp 
225                 230                 235                 240 


Glu Asp Pro Tyr Pro Gly 
                245     


<210>  2609
<211>  419
<212>  PRT
<213>  Homo Sapiens

<400>  2609

Val Ser Phe Gly Ile Arg Lys Leu Tyr Met Lys Ser Leu Leu Lys Ile 
1               5                   10                  15      


Phe Ala Trp Ala Thr Leu Arg Met Glu Arg Gly Ala Lys Glu Lys Asn 
            20                  25                  30          


His Gln Leu Tyr Lys Pro Tyr Thr Asn Gly Ile Ile Ala Lys Asp Pro 
        35                  40                  45              


Thr Ser Leu Glu Glu Glu Ile Lys Glu Ile Arg Arg Ser Gly Ser Ser 
    50                  55                  60                  


Lys Ala Leu Asp Asn Thr Pro Glu Phe Glu Leu Ser Asp Ile Phe Tyr 
65                  70                  75                  80  


Phe Cys Arg Lys Gly Met Glu Thr Ile Met Asp Asp Glu Val Thr Lys 
                85                  90                  95      


Arg Phe Ser Ala Glu Glu Leu Glu Ser Trp Asn Leu Leu Ser Arg Thr 
            100                 105                 110         


Asn Tyr Asn Phe Gln Tyr Ile Ser Leu Arg Leu Thr Val Leu Trp Gly 
        115                 120                 125             


Leu Gly Val Leu Ile Arg Tyr Cys Phe Leu Leu Pro Leu Arg Ile Ala 
    130                 135                 140                 


Leu Ala Phe Thr Gly Ile Ser Leu Leu Val Val Gly Thr Thr Val Val 
145                 150                 155                 160 


Gly Tyr Leu Pro Asn Gly Arg Phe Lys Glu Phe Met Ser Lys His Val 
                165                 170                 175     


His Leu Met Cys Tyr Arg Ile Cys Val Arg Ala Leu Thr Ala Ile Ile 
            180                 185                 190         


Thr Tyr His Asp Arg Glu Asn Arg Pro Arg Asn Gly Gly Ile Cys Val 
        195                 200                 205             


Ala Asn His Thr Ser Pro Ile Asp Val Ile Ile Leu Ala Ser Asp Gly 
    210                 215                 220                 


Tyr Tyr Ala Met Val Gly Gln Val His Gly Gly Leu Met Gly Val Ile 
225                 230                 235                 240 


Gln Arg Ala Met Val Lys Ala Cys Pro His Val Trp Phe Glu Arg Ser 
                245                 250                 255     


Glu Val Lys Asp Arg His Leu Val Ala Lys Arg Leu Thr Glu His Val 
            260                 265                 270         


Gln Asp Lys Ser Lys Leu Pro Ile Leu Ile Phe Pro Glu Gly Thr Cys 
        275                 280                 285             


Ile Asn Asn Thr Ser Val Met Met Phe Lys Lys Gly Ser Phe Glu Ile 
    290                 295                 300                 


Gly Ala Thr Val Tyr Pro Val Ala Ile Lys Tyr Asp Pro Gln Phe Gly 
305                 310                 315                 320 


Asp Ala Phe Trp Asn Ser Ser Lys Tyr Gly Met Val Thr Tyr Leu Leu 
                325                 330                 335     


Arg Met Met Thr Ser Trp Ala Ile Val Cys Ser Val Trp Tyr Leu Pro 
            340                 345                 350         


Pro Met Thr Arg Glu Ala Asp Glu Asp Ala Val Gln Phe Ala Asn Arg 
        355                 360                 365             


Val Lys Ser Ala Ile Ala Arg Gln Gly Gly Leu Val Asp Leu Leu Trp 
    370                 375                 380                 


Asp Gly Gly Leu Lys Arg Glu Lys Val Lys Asp Thr Phe Lys Glu Glu 
385                 390                 395                 400 


Gln Gln Lys Leu Tyr Ser Lys Met Ile Val Gly Asn His Lys Asp Arg 
                405                 410                 415     


Ser Arg Ser 
            


<210>  2610
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2610

Ser Pro Ala Leu Gln Asp Leu Gln Ala Thr Glu Ala Asn Cys Thr Val 
1               5                   10                  15      


Leu Ser Val Gln Gln Ile Gly Glu Val Phe Glu Cys Thr Phe Thr Cys 
            20                  25                  30          


Gly Ala Asp Cys Arg Gly Thr Ser Gln Tyr Pro Cys Val Gln Val Tyr 
        35                  40                  45              


Val Asn Asn Ser Glu Ser Asn Ser Arg Ala Leu Leu His Ser Asp Glu 
    50                  55                  60                  


His Gln Leu Leu Thr Asn Pro Lys Cys Ser Tyr Ile Pro Pro Cys Lys 
65                  70                  75                  80  


Arg Glu Asn Gln Lys Asn Leu Glu Ser Val Met Asn Trp Gln Gln Tyr 
                85                  90                  95      


Trp Lys Asp Glu Ile Gly Ser Gln Pro Phe Thr Cys Tyr Phe Asn Gln 
            100                 105                 110         


His Gln Arg Pro Asp Asp Val Leu Leu His Arg Thr His Asp Glu 
        115                 120                 125         


<210>  2611
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  2611

Ala Asn Ala Pro Ser Ala Tyr Pro Arg Pro Ser Ser Thr Lys Ser Thr 
1               5                   10                  15      


Pro Ala Ser Gln Val Tyr Ser Leu Asn Thr Asp Phe Ala Phe Arg Leu 
            20                  25                  30          


Tyr Arg Arg Leu Val Leu Glu Thr Pro Ser Gln Asn Ile Phe Phe Ser 
        35                  40                  45              


Pro Val Ser Val Ser Thr Ser Leu Ala Met Leu Ser Leu Gly Ala His 
    50                  55                  60                  


Ser Val Thr Lys Thr Gln Ile Leu Gln Gly Leu Gly Phe Asn Leu Thr 
65                  70                  75                  80  


His Thr Pro Glu Ser Ala Ile His Gln Gly Phe Gln His Leu Val His 
                85                  90                  95      


Ser Leu Thr Val Pro Ser Lys Asp Leu Thr Leu Lys Met Gly Ser Ala 
            100                 105                 110         


Leu Phe Val Lys Lys Glu Leu Gln Leu Gln Ala Asn Phe Leu Gly Asn 
        115                 120                 125             


Val Lys Arg Leu Tyr Glu Ala Glu Val Phe Ser Thr Asp Phe Ser Asn 
    130                 135                 140                 


Pro Ser Ile Ala Gln Ala Arg Ile Asn Ser His Val Lys Lys Lys Thr 
145                 150                 155                 160 


Gln Gly Lys Val Val Asp Ile Ile Gln Gly Leu Asp Leu Leu Thr Ala 
                165                 170                 175     


Met Val Leu Val Asn His Ile Phe Phe Lys Ala Lys Trp Glu Lys Pro 
            180                 185                 190         


Phe His Pro Glu Tyr Thr Arg Lys Asn Phe Pro Phe Leu Val Gly Glu 
        195                 200                 205             


Gln Val Thr Val His Val Pro Met Met His Gln Lys Glu Gln Phe Ala 
    210                 215                 220                 


Phe Gly Val Asp Thr Glu Leu Asn Cys Phe Val Leu Gln Met Asp Tyr 
225                 230                 235                 240 


Lys Gly Asp Ala Val Ala Phe Phe Val Leu Pro Ser Lys Gly Lys Met 
                245                 250                 255     


Arg Gln Leu Glu Gln Ala Leu Ser Ala Arg Thr Leu Arg Lys Trp Ser 
            260                 265                 270         


His Ser Leu Gln Lys Arg Trp Ile Glu Val Phe Ile Pro Arg Phe Ser 
        275                 280                 285             


Ile Ser Ala Ser Tyr Asn Leu Glu Thr Ile Leu Pro Lys Met Gly Ile 
    290                 295                 300                 


Gln Asn Val Phe Asp Lys Asn Ala Asp Phe Ser Gly Ile Ala Lys Arg 
305                 310                 315                 320 


Asp Ser Leu Gln Val Ser Lys Ala Thr His Lys Ala Val Leu Asp Val 
                325                 330                 335     


Ser Glu Glu Gly Thr Glu Ala Thr Ala Ala Thr Thr Thr Lys Phe Ile 
            340                 345                 350         


Val Arg Ser Lys Asp Gly Pro Ser Tyr Phe Thr Val Ser Phe Asn Arg 
        355                 360                 365             


Thr Phe Leu Met Met Ile Thr Asn Lys Ala Thr Asp Gly Ile Leu Phe 
    370                 375                 380                 


Leu Gly Lys Val Glu Asn Pro Thr Lys Ser 
385                 390                 


<210>  2612
<211>  65
<212>  PRT
<213>  Homo Sapiens

<400>  2612

Val Thr Ser Ser Thr Ser Tyr Phe Leu Pro Tyr Trp Leu Phe Gly Ser 
1               5                   10                  15      


Gln Met Gly Lys Pro Val Ser Phe Ser Thr Phe Arg Arg Cys Asn Tyr 
            20                  25                  30          


Pro Val Arg Gly Glu Gly His Ser Leu Ile Met Val Glu Glu Cys Gly 
        35                  40                  45              


Arg Tyr Ala Ser Phe Asn Ala Ile Pro Ser Leu Ala Trp Gln Met Cys 
    50                  55                  60                  


Thr 
65  


<210>  2613
<211>  304
<212>  PRT
<213>  Homo Sapiens

<400>  2613

Asp His Tyr Ser Pro Ser Gly Arg His Arg Leu Gly Pro Ser Pro Glu 
1               5                   10                  15      


Pro Ala Ala Ser Ser Gln Gln Ala Glu Ala Val Arg Lys Arg Leu Arg 
            20                  25                  30          


Arg Arg Arg Glu Gly Gly Ala His Ala Lys Asp Cys Gly Thr Ala Pro 
        35                  40                  45              


Leu Lys Asp Val Leu Gln Gly Ser Arg Ile Ile Gly Gly Thr Glu Ala 
    50                  55                  60                  


Gln Ala Gly Ala Trp Pro Trp Val Val Ser Leu Gln Ile Lys Tyr Gly 
65                  70                  75                  80  


Arg Val Leu Val His Val Cys Gly Gly Thr Leu Val Arg Glu Arg Trp 
                85                  90                  95      


Val Leu Thr Ala Ala His Cys Thr Lys Asp Ala Ser Asp Pro Leu Met 
            100                 105                 110         


Trp Thr Ala Val Ile Gly Thr Asn Asn Ile His Gly Arg Tyr Pro His 
        115                 120                 125             


Thr Lys Lys Ile Lys Ile Lys Ala Ile Ile Ile His Pro Asn Phe Ile 
    130                 135                 140                 


Leu Glu Ser Tyr Val Asn Asp Ile Ala Leu Phe His Leu Lys Lys Ala 
145                 150                 155                 160 


Val Arg Tyr Asn Asp Tyr Ile Gln Pro Ile Cys Leu Pro Phe Asp Val 
                165                 170                 175     


Phe Gln Ile Leu Asp Gly Asn Thr Lys Cys Phe Ile Ser Gly Trp Gly 
            180                 185                 190         


Arg Thr Lys Glu Glu Gly Asn Ala Thr Asn Ile Leu Gln Asp Ala Glu 
        195                 200                 205             


Val His Tyr Ile Ser Arg Glu Met Cys Asn Ser Glu Arg Ser Tyr Gly 
    210                 215                 220                 


Gly Ile Ile Pro Asn Thr Ser Phe Cys Ala Gly Asp Glu Asp Gly Ala 
225                 230                 235                 240 


Phe Asp Thr Cys Arg Gly Asp Ser Gly Gly Pro Leu Met Cys Tyr Leu 
                245                 250                 255     


Pro Glu Tyr Lys Arg Phe Phe Val Met Gly Ile Thr Ser Tyr Gly His 
            260                 265                 270         


Gly Cys Gly Arg Arg Gly Phe Pro Gly Val Tyr Ile Gly Pro Ser Phe 
        275                 280                 285             


Tyr Gln Lys Trp Leu Thr Glu His Phe Phe His Ala Ser Thr Gln Gly 
    290                 295                 300                 


<210>  2614
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  2614

Tyr Glu Val Phe Asn Ile Ile Ser Pro Ser Asn Asn Gly Gly Asn Val 
1               5                   10                  15      


Gln Glu Thr Val Thr Ile Asp Asn Glu Lys Asn Thr Ala Ile Ile Asn 
            20                  25                  30          


Ile His Ala Gly Ser Cys Ser Ser Thr Thr Ile Phe Asp Tyr Lys His 
        35                  40                  45              


Gly Tyr Ile Ala Ser Arg Val Leu Ser Arg Arg Ala Cys Phe Ile Leu 
    50                  55                  60                  


Lys Met Asp His Gln Asn Ile Pro Pro Leu Asn Asn Leu Gln Trp Tyr 
65                  70                  75                  80  


Ile Tyr Glu Lys Gln Ala Leu Asp Asn Met Phe Ser Ser Lys Tyr Thr 
                85                  90                  95      


Trp Val Lys Tyr Asn Pro Leu Glu Ser Leu Ile Lys Asp Val Asp Trp 
            100                 105                 110         


Phe Leu Leu Gly Ser Pro Ile Glu Lys Leu Cys Lys His Ile Pro Leu 
        115                 120                 125             


Tyr Lys Gly Glu Val Val Glu Asn Thr His Asn Val Gly Ala Gly Gly 
    130                 135                 140                 


Cys Ala Lys Ala Gly Leu Leu Gly Ile Leu Gly Ile Ser Ile Cys Ala 
145                 150                 155                 160 


Asp Ile His Val 
                


<210>  2615
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  2615

Gln Val Thr Gly Val Leu Asp Asp Cys Leu Cys Asp Ile Asp Ser Ile 
1               5                   10                  15      


Asp Asn Phe Asn Thr Tyr Lys Ile Phe Pro Lys Ile Lys Lys Leu Gln 
            20                  25                  30          


Glu Arg Asp Tyr Phe Arg Tyr Tyr Lys Val Asn Leu Lys Arg Pro Cys 
        35                  40                  45              


Pro Phe Trp Ala Glu Asp Gly His Cys Ser Ile Lys Asp Cys His Val 
    50                  55                  60                  


Glu Pro Cys Pro Glu Ser Lys Ile Pro Val Gly Ile Lys Ala Gly His 
65                  70                  75                  80  


Ser Asn Lys Tyr Leu Lys Met Ala Asn Asn Thr Lys Glu Leu Glu Val 
                85                  90                  95      


Cys Glu Gln Ala Asn Lys Leu Gly Ala Ile Asn Ser Thr Leu Ser Asn 
            100                 105                 110         


Gln Ser Lys Glu Ala Phe Ile Asp Trp Ala Arg Tyr Asp Asp Ser Arg 
        115                 120                 125             


Asp His Phe Cys Glu Leu Asp Asp Glu Arg Ser Pro Ala Ala Gln Tyr 
    130                 135                 140                 


Val Asp Leu Leu Leu Asn Pro Glu Arg Tyr Thr Gly Tyr Lys Gly Thr 
145                 150                 155                 160 


Ser Ala Trp Arg Val Trp Asn Ser Ile Tyr Glu Glu Asn Cys Phe Lys 
                165                 170                 175     


Pro Arg Ser Val Tyr Arg Pro Leu Asn Pro Leu Ala Pro Ser Arg Gly 
            180                 185                 190         


Glu Asp Asp Gly Glu Ser Phe Tyr Thr Trp Leu Glu Gly Leu Cys Leu 
        195                 200                 205             


Glu Lys Arg Val Phe Tyr Lys Leu Ile Ser Gly Leu His Ala Ser Ile 
    210                 215                 220                 


Asn Leu His Leu Cys Ala Asn Tyr Leu Leu Glu Glu Thr Trp Gly Lys 
225                 230                 235                 240 


Pro Ser Trp Gly Pro Asn Ile Lys Glu Phe Lys His Arg Phe Asp Pro 
                245                 250                 255     


Val Glu Thr Lys Gly Glu Gly Pro Arg Arg Leu Lys Asn Leu Tyr Phe 
            260                 265                 270         


Leu Tyr Leu Ile Glu Leu Arg Ala Leu Ser Lys Val Ala Pro Tyr Phe 
        275                 280                 285             


Glu Arg Ser Ile Val Asp Leu Tyr Thr Gly Asn Ala Glu Glu Asp Ala 
    290                 295                 300                 


Asp Thr Lys Thr Leu Leu Leu Asn Ile Phe Gln Asp Thr Lys Ser Phe 
305                 310                 315                 320 


Pro Met His Phe Asp Glu Lys Ser Met Phe Ala Gly Asp Lys Lys Gly 
                325                 330                 335     


Ala Lys Ser Leu Lys Glu Glu Phe Arg Leu His Phe Lys Asn Ile Ser 
            340                 345                 350         


Arg Ile Met Asp Cys Val Gly Cys Asp Lys Cys Arg Leu Trp Gly Lys 
        355                 360                 365             


Leu Gln Thr Gln Gly Leu Gly Thr Ala Leu Lys Ile Leu Phe Ser Glu 
    370                 375                 380                 


Lys Glu Ile Gln Lys Leu Pro Glu Asn Ser Pro Ser Lys Gly Phe Gln 
385                 390                 395                 400 


Leu Thr Arg Gln Glu Ile Val Ala Leu Leu Asn Ala Phe Gly Arg Leu 
                405                 410                 415     


Ser Thr Ser Ile Arg Asp Leu Gln Asn Phe Lys Val Leu Leu Gln His 
            420                 425                 430         


Ser Arg 
        


<210>  2616
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  2616

Ala Ser Thr Gly Gln Pro Glu Asp Asp Thr Glu Thr Thr Gly Leu Glu 
1               5                   10                  15      


Gly Gly Val Ala Met Pro Gly Ala Glu Asp Asp Val Val Thr Pro Gly 
            20                  25                  30          


Thr Ser Glu Asp Arg Tyr Lys Ser Gly Leu Thr Thr Leu Val Ala Thr 
        35                  40                  45              


Ser Val Asn Ser Val Thr Gly Ile Arg Ile Glu Asp Leu Pro Thr Ser 
    50                  55                  60                  


Glu Ser Thr Val His Ala Gln Glu Gln Ser Pro Ser Ala Thr Ala Ser 
65                  70                  75                  80  


Asn Val Ala Thr Ser His Ser Thr Glu Lys Val Asp Gly Asp Thr Gln 
                85                  90                  95      


Thr Thr Val Glu Lys Asp Gly Leu Ser Thr Val Thr Leu 
            100                 105                 


<210>  2617
<211>  996
<212>  PRT
<213>  Homo Sapiens

<400>  2617

Met Lys Pro Gly Cys Ala Ala Gly Ser Pro Gly Asn Glu Trp Ile Phe 
1               5                   10                  15      


Phe Ser Thr Asp Glu Ile Thr Thr Arg Tyr Arg Asn Thr Met Ser Asn 
            20                  25                  30          


Gly Gly Leu Gln Arg Ser Val Ile Leu Ser Ala Leu Ile Leu Leu Arg 
        35                  40                  45              


Ala Val Thr Gly Phe Ser Gly Asp Gly Arg Ala Ile Trp Ser Lys Asn 
    50                  55                  60                  


Pro Asn Phe Thr Pro Val Asn Glu Ser Gln Leu Phe Leu Tyr Asp Thr 
65                  70                  75                  80  


Phe Pro Lys Asn Phe Phe Trp Gly Ile Gly Thr Gly Ala Leu Gln Val 
                85                  90                  95      


Glu Gly Ser Trp Lys Lys Asp Gly Lys Gly Pro Ser Ile Trp Asp His 
            100                 105                 110         


Phe Ile His Thr His Leu Lys Asn Val Ser Ser Thr Asn Gly Ser Ser 
        115                 120                 125             


Asp Ser Tyr Ile Phe Leu Glu Lys Asp Leu Ser Ala Leu Asp Phe Ile 
    130                 135                 140                 


Gly Val Ser Phe Tyr Gln Phe Ser Ile Ser Trp Pro Arg Leu Phe Pro 
145                 150                 155                 160 


Asp Gly Ile Val Thr Val Ala Asn Ala Lys Gly Leu Gln Tyr Tyr Ser 
                165                 170                 175     


Thr Leu Leu Asp Ala Leu Val Leu Arg Asn Ile Glu Pro Ile Val Thr 
            180                 185                 190         


Leu Tyr His Trp Asp Leu Pro Leu Ala Leu Gln Glu Lys Tyr Gly Gly 
        195                 200                 205             


Trp Lys Asn Asp Thr Ile Ile Asp Ile Phe Asn Asp Tyr Ala Thr Tyr 
    210                 215                 220                 


Cys Phe Gln Met Phe Gly Asp Arg Val Lys Tyr Trp Ile Thr Ile His 
225                 230                 235                 240 


Asn Pro Tyr Leu Val Ala Trp His Gly Tyr Gly Thr Gly Met His Ala 
                245                 250                 255     


Pro Gly Glu Lys Gly Asn Leu Ala Ala Val Tyr Thr Val Gly His Asn 
            260                 265                 270         


Leu Ile Lys Ala His Ser Lys Val Trp His Asn Tyr Asn Thr His Phe 
        275                 280                 285             


Arg Pro His Gln Lys Gly Trp Leu Ser Ile Thr Leu Gly Ser His Trp 
    290                 295                 300                 


Ile Glu Pro Asn Arg Ser Glu Asn Thr Met Asp Ile Phe Lys Cys Gln 
305                 310                 315                 320 


Gln Ser Met Val Ser Val Leu Gly Trp Phe Ala Asn Pro Ile His Gly 
                325                 330                 335     


Asp Gly Asp Tyr Pro Glu Gly Met Arg Lys Lys Leu Phe Ser Val Leu 
            340                 345                 350         


Pro Ile Phe Ser Glu Ala Glu Lys His Glu Met Arg Gly Thr Ala Asp 
        355                 360                 365             


Phe Phe Ala Phe Ser Phe Gly Pro Asn Asn Phe Lys Pro Leu Asn Thr 
    370                 375                 380                 


Met Ala Lys Met Gly Gln Asn Val Ser Leu Asn Leu Arg Glu Ala Leu 
385                 390                 395                 400 


Asn Trp Ile Lys Leu Glu Tyr Asn Asn Pro Arg Ile Leu Ile Ala Glu 
                405                 410                 415     


Asn Gly Trp Phe Thr Asp Ser Arg Val Lys Thr Glu Asp Thr Thr Ala 
            420                 425                 430         


Ile Tyr Met Met Lys Asn Phe Leu Ser Gln Val Leu Gln Ala Ile Arg 
        435                 440                 445             


Leu Asp Glu Ile Arg Val Phe Gly Tyr Thr Ala Trp Ser Leu Leu Asp 
    450                 455                 460                 


Gly Phe Glu Trp Gln Asp Ala Tyr Thr Ile Arg Arg Gly Leu Phe Tyr 
465                 470                 475                 480 


Val Asp Phe Asn Ser Lys Gln Lys Glu Arg Lys Pro Lys Ser Ser Ala 
                485                 490                 495     


His Tyr Tyr Lys Gln Ile Ile Arg Glu Asn Gly Phe Ser Leu Lys Glu 
            500                 505                 510         


Ser Thr Pro Asp Val Gln Gly Gln Phe Pro Cys Asp Phe Ser Trp Gly 
        515                 520                 525             


Val Thr Glu Ser Val Leu Lys Pro Glu Ser Val Ala Ser Ser Pro Gln 
    530                 535                 540                 


Phe Ser Asp Pro His Leu Tyr Val Trp Asn Ala Thr Gly Asn Arg Leu 
545                 550                 555                 560 


Leu His Arg Val Glu Gly Val Arg Leu Lys Thr Arg Pro Ala Gln Cys 
                565                 570                 575     


Thr Asp Phe Val Asn Ile Lys Lys Gln Leu Glu Met Leu Ala Arg Met 
            580                 585                 590         


Lys Val Thr His Tyr Arg Phe Ala Leu Asp Trp Ala Ser Val Leu Pro 
        595                 600                 605             


Thr Gly Asn Leu Ser Ala Val Asn Arg Gln Ala Leu Arg Tyr Tyr Arg 
    610                 615                 620                 


Cys Val Val Ser Glu Gly Leu Lys Leu Gly Ile Ser Ala Met Val Thr 
625                 630                 635                 640 


Leu Tyr Tyr Pro Thr His Ala His Leu Gly Leu Pro Glu Pro Leu Leu 
                645                 650                 655     


His Ala Asp Gly Trp Leu Asn Pro Ser Thr Ala Glu Ala Phe Gln Ala 
            660                 665                 670         


Tyr Ala Gly Leu Cys Phe Gln Glu Leu Gly Asp Leu Val Lys Leu Trp 
        675                 680                 685             


Ile Thr Ile Asn Glu Pro Asn Arg Leu Ser Asp Ile Tyr Asn Arg Ser 
    690                 695                 700                 


Gly Asn Asp Thr Tyr Gly Ala Ala His Asn Leu Leu Val Ala His Ala 
705                 710                 715                 720 


Leu Ala Trp Arg Leu Tyr Asp Arg Gln Phe Arg Pro Ser Gln Arg Gly 
                725                 730                 735     


Ala Val Ser Leu Ser Leu His Ala Asp Trp Ala Glu Pro Ala Asn Pro 
            740                 745                 750         


Tyr Ala Asp Ser His Trp Arg Ala Ala Glu Arg Phe Leu Gln Phe Glu 
        755                 760                 765             


Ile Ala Trp Phe Ala Glu Pro Leu Phe Lys Thr Gly Asp Tyr Pro Ala 
    770                 775                 780                 


Ala Met Arg Glu Tyr Ile Ala Ser Lys His Arg Arg Gly Leu Ser Ser 
785                 790                 795                 800 


Ser Ala Leu Pro Arg Leu Thr Glu Ala Glu Arg Arg Leu Leu Lys Gly 
                805                 810                 815     


Thr Val Asp Phe Cys Ala Leu Asn His Phe Thr Thr Arg Phe Val Met 
            820                 825                 830         


His Glu Gln Leu Ala Gly Ser Arg Tyr Asp Ser Asp Arg Asp Ile Gln 
        835                 840                 845             


Phe Leu Gln Asp Ile Thr Arg Leu Ser Ser Pro Thr Arg Leu Ala Val 
    850                 855                 860                 


Ile Pro Trp Gly Val Arg Lys Leu Leu Arg Trp Val Arg Arg Asn Tyr 
865                 870                 875                 880 


Gly Asp Met Asp Ile Tyr Ile Thr Ala Ser Gly Ile Asp Asp Gln Ala 
                885                 890                 895     


Leu Glu Asp Asp Arg Leu Arg Lys Tyr Tyr Leu Gly Lys Tyr Leu Gln 
            900                 905                 910         


Glu Val Leu Lys Ala Tyr Leu Ile Asp Lys Val Arg Ile Lys Gly Tyr 
        915                 920                 925             


Tyr Ala Phe Lys Leu Ala Glu Glu Lys Ser Lys Pro Arg Phe Gly Phe 
    930                 935                 940                 


Phe Thr Ser Asp Phe Lys Ala Lys Ser Ser Ile Gln Phe Tyr Asn Lys 
945                 950                 955                 960 


Val Ile Ser Ser Arg Gly Phe Pro Phe Glu Asn Ser Ser Ser Arg Cys 
                965                 970                 975     


Ser Gln Thr Gln Glu Asn Thr Glu Cys Thr Val Cys Leu Phe Leu Val 
            980                 985                 990         


Gln Lys Lys Pro 
        995     


<210>  2618
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2618

Ser Arg Gly Pro Ala His Tyr Glu Met Leu Gly Arg Cys Arg Met Val 
1               5                   10                  15      


Cys Asp Pro His Gly Pro Arg Gly Pro Gly Pro Asp Gly Ala Pro Ala 
            20                  25                  30          


Ser Val Pro Pro Phe Pro Pro Gly Ala Lys Gly Glu Val Gly Arg Arg 
        35                  40                  45              


Gly Lys Ala Gly Leu Arg Gly Pro Pro Gly Pro Pro Gly Pro Arg Gly 
    50                  55                  60                  


Pro Pro Gly Glu Pro Gly Arg Pro Gly Pro Pro Gly Pro Pro Gly Pro 
65                  70                  75                  80  


Gly Pro Gly Gly Val Ala Pro Ala Ala Gly Tyr Val Pro Arg Ile Ala 
                85                  90                  95      


Phe Tyr Ala Gly Leu Arg Arg Pro His Glu Gly Tyr Glu Val Leu Arg 
            100                 105                 110         


Phe Asp Asp Val Val Thr Asn Val Gly Asn Ala Tyr Glu Ala Ala Ser 
        115                 120                 125             


Gly Lys Phe Thr Cys Pro Met Pro Gly Val Tyr Phe Phe Ala Tyr His 
    130                 135                 140                 


Val Leu Met Arg Gly Gly Asp Gly Thr Ser Met Trp Ala Asp Leu Met 
145                 150                 155                 160 


Lys Asn Gly Gln Val Arg Ala Ser Ala Ile Ala Gln Asp Ala Asp Gln 
                165                 170                 175     


Asn Tyr Asp Tyr Ala Ser Asn Ser Val Ile Leu His Leu Asp Val Gly 
            180                 185                 190         


Asp Glu Val Phe Ile Lys Leu Asp Gly Gly Lys Val His Gly Gly Asn 
        195                 200                 205             


Thr Asn Lys Tyr Ser Thr Phe Ser Gly Phe Ile Ile Tyr Pro Asp 
    210                 215                 220             


<210>  2619
<211>  757
<212>  PRT
<213>  Homo Sapiens

<400>  2619

Gly Tyr Lys Ala Glu Val Met Val Ser Gln Val Tyr Ser Gly Ser Leu 
1               5                   10                  15      


Arg Val Leu Asn Arg His Phe Ser Gln Asp Leu Thr Arg Arg Glu Ser 
            20                  25                  30          


Ser Ala Phe Arg Ser Glu Thr Ala Lys Ala Gln Lys Met Leu Lys Glu 
        35                  40                  45              


Leu Ile Thr Ser Thr Arg Leu Gly Thr Tyr Tyr Asn Ser Ser Ser Val 
    50                  55                  60                  


Tyr Ser Phe Gly Glu Gly Pro Leu Thr Cys Phe Phe Trp Phe Ile Leu 
65                  70                  75                  80  


Gln Ile Pro Glu His Arg Arg Leu Met Leu Ser Pro Glu Val Val Gln 
                85                  90                  95      


Ala Leu Leu Val Glu Glu Leu Leu Ser Thr Val Asn Ser Ser Ala Ala 
            100                 105                 110         


Val Pro Tyr Arg Ala Glu Tyr Glu Val Asp Pro Glu Gly Leu Val Ile 
        115                 120                 125             


Leu Glu Ala Ser Val Lys Asp Ile Ala Ala Leu Asn Ser Thr Leu Gly 
    130                 135                 140                 


Cys Tyr Arg Tyr Ser Tyr Val Gly Gln Gly Gln Val Leu Arg Leu Lys 
145                 150                 155                 160 


Gly Pro Asp His Leu Ala Ser Ser Cys Leu Trp His Leu Gln Gly Pro 
                165                 170                 175     


Lys Asp Leu Met Leu Lys Leu Arg Leu Glu Trp Thr Leu Ala Glu Cys 
            180                 185                 190         


Arg Asp Arg Leu Ala Met Tyr Asp Val Ala Gly Pro Leu Glu Lys Arg 
        195                 200                 205             


Leu Ile Thr Ser Val Tyr Gly Cys Ser Arg Gln Glu Pro Val Val Glu 
    210                 215                 220                 


Val Leu Ala Ser Gly Ala Ile Met Ala Val Val Trp Lys Lys Gly Leu 
225                 230                 235                 240 


His Ser Tyr Tyr Asp Pro Phe Val Leu Ser Val Gln Pro Val Val Phe 
                245                 250                 255     


Gln Ala Cys Glu Val Asn Leu Thr Leu Asp Asn Arg Leu Asp Ser Gln 
            260                 265                 270         


Gly Val Leu Ser Thr Pro Tyr Phe Pro Ser Tyr Tyr Ser Pro Gln Thr 
        275                 280                 285             


His Cys Ser Trp His Leu Thr Val Pro Ser Leu Asp Tyr Gly Leu Ala 
    290                 295                 300                 


Leu Trp Phe Asp Ala Tyr Ala Leu Arg Arg Gln Lys Tyr Asp Leu Pro 
305                 310                 315                 320 


Cys Thr Gln Gly Gln Trp Thr Ile Gln Asn Arg Arg Leu Cys Gly Leu 
                325                 330                 335     


Arg Ile Leu Gln Pro Tyr Ala Glu Arg Ile Pro Val Val Ala Thr Ala 
            340                 345                 350         


Gly Ile Thr Ile Asn Phe Thr Ser Gln Ile Ser Leu Thr Gly Pro Gly 
        355                 360                 365             


Val Arg Val His Tyr Gly Leu Tyr Asn Gln Ser Asp Pro Cys Pro Gly 
    370                 375                 380                 


Glu Phe Leu Cys Ser Val Asn Gly Leu Cys Val Pro Ala Cys Asp Gly 
385                 390                 395                 400 


Val Lys Asp Cys Pro Asn Gly Leu Asp Glu Arg Asn Cys Val Cys Arg 
                405                 410                 415     


Ala Thr Phe Gln Cys Lys Glu Asp Ser Thr Cys Ile Ser Leu Pro Lys 
            420                 425                 430         


Val Cys Asp Gly Gln Pro Asp Cys Leu Asn Gly Ser Asp Glu Glu Gln 
        435                 440                 445             


Cys Gln Glu Gly Val Pro Cys Gly Thr Phe Thr Phe Gln Cys Glu Asp 
    450                 455                 460                 


Arg Ser Cys Val Lys Lys Pro Asn Pro Gln Cys Asp Gly Arg Pro Asp 
465                 470                 475                 480 


Cys Arg Asp Gly Ser Asp Glu Glu His Cys Asp Cys Gly Leu Gln Gly 
                485                 490                 495     


Pro Ser Ser Arg Ile Val Gly Gly Ala Val Ser Ser Glu Gly Glu Trp 
            500                 505                 510         


Pro Trp Gln Ala Ser Leu Gln Val Arg Gly Arg His Ile Cys Gly Gly 
        515                 520                 525             


Ala Leu Ile Ala Asp Arg Trp Val Ile Thr Ala Ala His Cys Phe Gln 
    530                 535                 540                 


Glu Asp Ser Met Ala Ser Thr Val Leu Trp Thr Val Phe Leu Gly Lys 
545                 550                 555                 560 


Val Trp Gln Asn Ser Arg Trp Pro Gly Glu Val Ser Phe Lys Val Ser 
                565                 570                 575     


Arg Leu Leu Leu His Pro Tyr His Glu Glu Asp Ser His Asp Tyr Asp 
            580                 585                 590         


Val Ala Leu Leu Gln Leu Asp His Pro Val Val Arg Ser Ala Ala Val 
        595                 600                 605             


Arg Pro Val Cys Leu Pro Ala Arg Ser His Phe Phe Glu Pro Gly Leu 
    610                 615                 620                 


His Cys Trp Ile Thr Gly Trp Gly Ala Leu Arg Glu Gly Ala Leu Arg 
625                 630                 635                 640 


Ala Asp Ala Val Ala Leu Phe Tyr Gly Trp Arg Asn Gln Gly Ser Glu 
                645                 650                 655     


Thr Cys Cys Cys Pro Ile Ser Asn Ala Leu Gln Lys Val Asp Val Gln 
            660                 665                 670         


Leu Ile Pro Gln Asp Leu Cys Ser Glu Val Tyr Arg Tyr Gln Val Thr 
        675                 680                 685             


Pro Arg Met Leu Cys Ala Gly Tyr Arg Lys Gly Lys Lys Asp Ala Cys 
    690                 695                 700                 


Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Lys Ala Leu Ser Gly Arg 
705                 710                 715                 720 


Trp Phe Leu Ala Gly Leu Val Ser Trp Gly Leu Gly Cys Gly Arg Pro 
                725                 730                 735     


Asn Tyr Phe Gly Val Tyr Thr Arg Ile Thr Gly Val Ile Ser Trp Ile 
            740                 745                 750         


Gln Gln Val Val Thr 
        755         


<210>  2620
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  2620

Cys Thr Ala Val Pro Val Ser Ala Leu Gly Asn Gly Ser Leu Ala Pro 
1               5                   10                  15      


Gly Leu Pro Ala Pro Glu Leu Ala Arg Leu Leu Ala Arg Val Pro Cys 
            20                  25                  30          


Pro Glu Ile Tyr Asp Gly Asp Trp Leu Leu Ala Arg Glu Val Ala Val 
        35                  40                  45              


Arg Tyr Leu Arg 
    50          


<210>  2621
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  2621

Gly Glu His Ala Lys Glu Gly Glu Cys Pro Pro His Lys Asn Pro Cys 
1               5                   10                  15      


Lys Glu Leu Cys Gln Gly Asp Glu Leu Cys Pro Ala Glu Gln Lys Cys 
            20                  25                  30          


Cys Thr Thr Gly Cys Gly Arg Ile Cys Arg Asp Ile Pro Lys Gly Arg 
        35                  40                  45              


Lys Arg Asp Cys Pro Arg Val Ile Arg Lys Gln Ser Cys Leu Lys Arg 
    50                  55                  60                  


Cys Ile Thr Asp Glu Thr Cys Pro Gly Val Lys Lys Cys Cys Thr Leu 
65                  70                  75                  80  


Gly Cys Asn Lys Ser Cys Val Val Pro Ile Ser Lys Gln Lys Leu Ala 
                85                  90                  95      


Glu Phe Gly Gly Glu Cys Pro Ala Asp Pro Leu Pro Cys Glu Glu Leu 
            100                 105                 110         


Cys Asp Gly Asp Ala Ser Cys Pro Gln Gly His Lys Cys Cys Ser Thr 
        115                 120                 125             


Gly Cys Gly Arg Thr Cys Leu Gly Asp Ile Glu Gly Gly Arg Gly Gly 
    130                 135                 140                 


Asp Cys Pro Lys Val Leu Val Gly Leu Cys Ile Val Gly Cys Val Met 
145                 150                 155                 160 


Asp Glu Asn Cys Gln Ala Gly Glu Lys Cys Cys Lys Ser Gly Cys Gly 
                165                 170                 175     


Arg Phe Cys Val Pro Pro Val Leu Pro Pro Lys Leu Thr Met Asn Pro 
            180                 185                 190         


Asn Trp Thr Val Arg Ser Asp Ser Glu Leu Glu Ile Pro Val Pro 
        195                 200                 205         


<210>  2622
<211>  259
<212>  PRT
<213>  Homo Sapiens

<400>  2622

Tyr Val Ile Val Ser Ser Val Ser Trp Ala Val Thr Asn Glu Val Asp 
1               5                   10                  15      


Glu Glu Leu Asp Ser Ala Ser Thr Glu Glu Ala Met Pro Ala Leu Leu 
            20                  25                  30          


Glu Asp Ser Gly Ser Ile Trp Gln Gln Ser Phe Pro Ala Ser Ala His 
        35                  40                  45              


Lys Glu Asp Ala His Leu Arg Pro Arg Ala Gly Ala Ala Arg Ala Arg 
    50                  55                  60                  


Gln Pro Pro Ala Pro Pro Gly Met Phe Ser Tyr Arg Arg Glu Gly Gly 
65                  70                  75                  80  


Gln Thr Ala Ser Ala Pro Pro Gly Pro Arg Leu Arg Ala Ala Thr Ala 
                85                  90                  95      


Arg Ser Leu Ala His Ala Ser Val Trp Gly Cys Leu Ala Thr Val Ser 
            100                 105                 110         


Thr His Lys Lys Ile Gln Gly Leu Pro Phe Gly Asn Cys Leu Pro Val 
        115                 120                 125             


Ser Asp Gly Pro Phe Asn Asn Ser Thr Gly Ile Pro Phe Phe Tyr Met 
    130                 135                 140                 


Thr Ala Lys Asp Pro Val Val Ala Asp Leu Met Lys Asn Pro Met Ala 
145                 150                 155                 160 


Ser Leu Met Leu Pro Glu Ser Glu Gly Glu Phe Cys Arg Lys Asn Ile 
                165                 170                 175     


Val Asp Pro Glu Asp Pro Arg Cys Val Gln Leu Thr Leu Thr Gly Gln 
            180                 185                 190         


Met Ile Ala Val Ser Pro Glu Glu Val Glu Phe Ala Lys Gln Ala Met 
        195                 200                 205             


Phe Ser Arg His Pro Gly Met Arg Lys Trp Pro Arg Gln Tyr Glu Trp 
    210                 215                 220                 


Phe Phe Met Lys Met Arg Ile Glu His Ile Trp Leu Gln Lys Trp Tyr 
225                 230                 235                 240 


Gly Gly Ala Ser Ser Ile Ser Arg Glu Glu Tyr Phe Lys Ala Val Pro 
                245                 250                 255     


Arg Lys Ala 
            


<210>  2623
<211>  408
<212>  PRT
<213>  Homo Sapiens

<400>  2623

Leu Ser Pro Gln Pro Gly Ala Gly His Asp Glu Gly Pro Gly Ser Gly 
1               5                   10                  15      


Trp Ala Ala Lys Gly Thr Val Arg Gly Trp Asn Arg Arg Ala Arg Glu 
            20                  25                  30          


Ser Pro Gly His Val Ser Glu Pro Asp Arg Thr Gln Leu Ser Gln Asp 
        35                  40                  45              


Leu Gly Gly Gly Thr Leu Ala Met Asp Thr Leu Pro Asp Asn Arg Thr 
    50                  55                  60                  


Arg Val Val Glu Asp Asn His Ser Tyr Tyr Val Ser Arg Leu Tyr Gly 
65                  70                  75                  80  


Pro Ser Glu Pro His Ser Arg Glu Leu Trp Val Asp Val Ala Glu Ala 
                85                  90                  95      


Asn Arg Ser Gln Val Lys Ile His Thr Ile Leu Ser Asn Thr His Arg 
            100                 105                 110         


Gln Ala Ser Arg Val Val Leu Ser Phe Asp Phe Pro Phe Tyr Gly His 
        115                 120                 125             


Pro Leu Arg Gln Ile Thr Met Ala Thr Gly Gly Phe Ile Phe Met Gly 
    130                 135                 140                 


Asp Val Ile His Arg Met Leu Thr Ala Thr Gln Tyr Val Ala Pro Leu 
145                 150                 155                 160 


Met Ala Asn Phe Asn Pro Gly Tyr Ser Asp Asn Ser Thr Val Val Tyr 
                165                 170                 175     


Phe Asp Asn Gly Thr Val Phe Val Val Gln Trp Asp His Val Tyr Leu 
            180                 185                 190         


Gln Gly Trp Glu Asp Lys Gly Ser Phe Thr Phe Gln Ala Ala Leu His 
        195                 200                 205             


His Asp Gly Arg Ile Val Phe Ala Tyr Lys Glu Ile Pro Met Ser Val 
    210                 215                 220                 


Pro Glu Ile Ser Ser Ser Gln His Pro Val Lys Thr Gly Leu Ser Asp 
225                 230                 235                 240 


Ala Phe Met Ile Leu Asn Pro Ser Pro Asp Val Pro Glu Ser Arg Arg 
                245                 250                 255     


Arg Ser Ile Phe Glu Tyr His Arg Ile Glu Leu Asp Pro Ser Lys Val 
            260                 265                 270         


Thr Ser Met Ser Ala Val Glu Phe Thr Pro Leu Pro Thr Cys Leu Gln 
        275                 280                 285             


His Arg Ser Cys Asp Ala Cys Met Ser Ser Asp Leu Thr Phe Asn Cys 
    290                 295                 300                 


Ser Trp Cys His Val Leu Gln Arg Cys Ser Ser Gly Phe Asp Arg Tyr 
305                 310                 315                 320 


Arg Gln Glu Trp Met Asp Tyr Gly Cys Ala Gln Glu Ala Glu Gly Arg 
                325                 330                 335     


Met Cys Glu Asp Phe Gln Asp Glu Asp His Asp Ser Ala Ser Pro Asp 
            340                 345                 350         


Thr Ser Phe Ser Pro Tyr Asp Gly Asp Leu Thr Thr Thr Ser Ser Ser 
        355                 360                 365             


Leu Phe Ile Asp Ser Leu Thr Thr Glu Asp Asp Thr Lys Leu Asn Pro 
    370                 375                 380                 


Tyr Ala Gly Gly Asp Gly Leu Gln Asn Asn Leu Ser Pro Lys Thr Lys 
385                 390                 395                 400 


Gly Thr Pro Val His Leu Gly Thr 
                405             


<210>  2624
<211>  716
<212>  PRT
<213>  Homo Sapiens

<400>  2624

Glu Pro Pro Gly Leu Thr Gln Leu Ser Pro Gly Ala Pro Pro Gln Ala 
1               5                   10                  15      


Pro Asp Leu Leu Tyr Ala Asp Gly Leu Arg Ala Tyr Ala Ala Gly Ala 
            20                  25                  30          


Trp Ala Pro Ala Val Ala Leu Leu Arg Glu Ala Leu Arg Ser Gln Ala 
        35                  40                  45              


Ala Leu Gly Arg Val Arg Leu Asp Cys Gly Ala Ser Cys Ala Ala Asp 
    50                  55                  60                  


Pro Gly Ala Ala Leu Pro Ala Val Leu Leu Gly Ala Pro Glu Pro Asp 
65                  70                  75                  80  


Ser Gly Pro Gly Pro Thr Gln Gly Ser Trp Glu Arg Gln Leu Leu Arg 
                85                  90                  95      


Ala Ala Leu Arg Arg Ala Asp Cys Leu Thr Gln Cys Ala Ala Arg Arg 
            100                 105                 110         


Leu Gly Pro Gly Gly Ala Ala Arg Leu Arg Val Gly Ser Ala Leu Arg 
        115                 120                 125             


Asp Ala Phe Arg Arg Arg Glu Pro Tyr Asn Tyr Leu Gln Arg Ala Tyr 
    130                 135                 140                 


Tyr Gln Leu Lys Lys Leu Asp Leu Ala Ala Ala Ala Ala His Thr Phe 
145                 150                 155                 160 


Phe Val Ala Asn Pro Met His Leu Gln Met Arg Glu Asp Met Ala Lys 
                165                 170                 175     


Tyr Arg Arg Met Ser Gly Val Arg Pro Gln Ser Phe Arg Asp Leu Glu 
            180                 185                 190         


Thr Pro Pro His Trp Ala Ala Tyr Asp Thr Gly Leu Glu Leu Leu Gly 
        195                 200                 205             


Arg Gln Glu Ala Gly Leu Ala Leu Pro Arg Leu Glu Glu Ala Leu Gln 
    210                 215                 220                 


Gly Ser Leu Ala Gln Met Glu Ser Cys Arg Ala Asp Cys Glu Gly Pro 
225                 230                 235                 240 


Glu Glu Gln Gln Gly Ala Glu Glu Glu Glu Asp Gly Ala Ala Ser Gln 
                245                 250                 255     


Gly Gly Leu Tyr Glu Ala Ile Ala Gly His Trp Ile Gln Val Leu Gln 
            260                 265                 270         


Cys Arg Gln Arg Cys Val Gly Glu Thr Ala Thr Arg Pro Gly Arg Ser 
        275                 280                 285             


Phe Pro Val Pro Asp Phe Leu Pro Asn Gln Leu Arg Arg Leu His Glu 
    290                 295                 300                 


Ala His Ala Gln Val Gly Asn Leu Ser Gln Ala Ile Glu Asn Val Leu 
305                 310                 315                 320 


Ser Val Leu Leu Phe Tyr Pro Glu Asp Glu Ala Ala Lys Arg Ala Leu 
                325                 330                 335     


Asn Gln Tyr Gln Ala Gln Leu Gly Glu Pro Arg Pro Gly Leu Gly Pro 
            340                 345                 350         


Arg Glu Asp Ile Gln Arg Phe Ile Leu Arg Ser Leu Gly Glu Lys Arg 
        355                 360                 365             


Gln Leu Tyr Tyr Ala Met Glu His Leu Gly Thr Ser Phe Lys Asp Pro 
    370                 375                 380                 


Asp Pro Trp Thr Pro Ala Ala Leu Ile Pro Glu Ala Leu Arg Glu Lys 
385                 390                 395                 400 


Leu Arg Glu Asp Gln Glu Lys Arg Pro Trp Asp His Glu Pro Val Lys 
                405                 410                 415     


Pro Lys Pro Leu Thr Tyr Trp Lys Asp Val Leu Leu Leu Glu Gly Val 
            420                 425                 430         


Thr Leu Thr Gln Asp Ser Arg Gln Leu Asn Gly Ser Glu Arg Ala Val 
        435                 440                 445             


Leu Asp Gly Leu Leu Thr Pro Ala Glu Cys Gly Val Leu Leu Gln Leu 
    450                 455                 460                 


Ala Lys Asp Ala Ala Gly Ala Gly Ala Arg Ser Gly Tyr Arg Gly Arg 
465                 470                 475                 480 


Arg Ser Pro His Thr Pro His Glu Arg Phe Glu Gly Leu Thr Val Leu 
                485                 490                 495     


Lys Ala Ala Gln Leu Ala Arg Ala Gly Thr Val Gly Ser Gln Gly Ala 
            500                 505                 510         


Lys Leu Leu Leu Glu Val Ser Glu Arg Val Arg Thr Leu Thr Gln Ala 
        515                 520                 525             


Tyr Phe Ser Pro Glu Arg Pro Leu His Leu Ser Phe Thr His Leu Val 
    530                 535                 540                 


Cys Arg Ser Ala Ile Glu Gly Glu Gln Glu Gln Arg Met Asp Leu Ser 
545                 550                 555                 560 


His Pro Val His Ala Asp Asn Cys Val Leu Asp Pro Asp Thr Gly Glu 
                565                 570                 575     


Cys Trp Arg Glu Pro Pro Ala Tyr Thr Tyr Arg Asp Tyr Ser Gly Leu 
            580                 585                 590         


Leu Tyr Leu Asn Asp Asp Phe Gln Gly Gly Asp Leu Phe Phe Thr Glu 
        595                 600                 605             


Pro Asn Ala Leu Thr Val Thr Ala Arg Val Arg Pro Arg Cys Gly Arg 
    610                 615                 620                 


Leu Val Ala Phe Ser Ser Gly Val Glu Asn Pro His Gly Val Trp Ala 
625                 630                 635                 640 


Val Thr Arg Gly Arg Arg Cys Ala Leu Ala Leu Trp His Thr Trp Ala 
                645                 650                 655     


Pro Glu His Arg Glu Gln Glu Trp Ile Glu Ala Lys Glu Leu Leu Gln 
            660                 665                 670         


Glu Ser Gln Glu Glu Glu Glu Glu Glu Glu Glu Glu Met Pro Ser Lys 
        675                 680                 685             


Asp Pro Ser Pro Glu Pro Pro Ser Arg Arg His Gln Arg Val Gln Asp 
    690                 695                 700                 


Lys Thr Gly Arg Ala Pro Arg Val Arg Glu Glu Leu 
705                 710                 715     


<210>  2625
<211>  332
<212>  PRT
<213>  Homo Sapiens

<400>  2625

Tyr Asp Arg Ser Leu Ala Gln His Arg Gln Glu Ile Val Asp Lys Ser 
1               5                   10                  15      


Val Ser Pro Trp Ser Leu Glu Thr Tyr Ser Tyr Asn Ile Tyr His Pro 
            20                  25                  30          


Met Gly Glu Ile Tyr Glu Trp Met Arg Glu Ile Ser Glu Lys Tyr Lys 
        35                  40                  45              


Glu Val Val Thr Gln His Phe Leu Gly Val Thr Tyr Glu Thr His Pro 
    50                  55                  60                  


Ile Tyr Tyr Leu Lys Ile Ser Gln Pro Ser Gly Asn Pro Lys Lys Ile 
65                  70                  75                  80  


Ile Trp Met Asp Cys Gly Ile His Ala Arg Glu Trp Ile Ala Pro Ala 
                85                  90                  95      


Phe Cys Gln Trp Phe Val Lys Glu Ile Leu Gln Asn His Lys Asp Asn 
            100                 105                 110         


Ser Arg Ile Arg Lys Leu Leu Arg Asn Leu Asp Phe Tyr Val Leu Pro 
        115                 120                 125             


Val Leu Asn Ile Asp Gly Tyr Ile Tyr Thr Trp Thr Thr Asp Arg Leu 
    130                 135                 140                 


Trp Arg Lys Ser Arg Ser Pro His Asn Asn Gly Thr Cys Phe Gly Thr 
145                 150                 155                 160 


Asp Leu Asn Arg Asn Phe Asn Ala Ser Trp Cys Ser Ile Gly Ala Ser 
                165                 170                 175     


Arg Asn Cys Gln Asp Gln Thr Phe Cys Gly Thr Gly Pro Val Ser Glu 
            180                 185                 190         


Pro Glu Thr Lys Ala Val Ala Ser Phe Ile Glu Ser Lys Lys Asp Asp 
        195                 200                 205             


Ile Leu Cys Phe Leu Thr Met His Ser Tyr Gly Gln Leu Ile Leu Thr 
    210                 215                 220                 


Pro Tyr Gly Tyr Thr Lys Asn Lys Ser Ser Asn His Pro Glu Met Ile 
225                 230                 235                 240 


Gln Val Gly Gln Lys Ala Ala Asn Ala Leu Lys Ala Lys Tyr Gly Thr 
                245                 250                 255     


Asn Tyr Arg Val Gly Ser Ser Ala Asp Ile Leu Tyr Ala Ser Ser Gly 
            260                 265                 270         


Ser Ser Arg Asp Trp Ala Arg Asp Ile Gly Ile Pro Phe Ser Tyr Thr 
        275                 280                 285             


Phe Glu Leu Arg Asp Ser Gly Thr Tyr Gly Phe Val Leu Pro Glu Ala 
    290                 295                 300                 


Gln Ile Gln Pro Thr Cys Glu Glu Thr Met Glu Ala Val Leu Ser Val 
305                 310                 315                 320 


Leu Asp Asp Val Tyr Ala Lys His Trp His Ser Asp 
                325                 330         


<210>  2626
<211>  107
<212>  PRT
<213>  Homo Sapiens

<400>  2626

Leu Glu Asn Phe Thr Ala Phe Ile Pro Gly His Arg Cys Trp Val His 
1               5                   10                  15      


Ile Leu Asp Asn Asp Thr Val Ser Asp Asn Asp Thr Gly Ala Leu Ser 
            20                  25                  30          


Gln Asp Ala Leu Leu Arg Ile Ser Ile Pro Leu Asp Ser Asn Met Arg 
        35                  40                  45              


Pro Glu Lys Cys Arg Arg Phe Val His Pro Gln Trp Gln Leu Leu His 
    50                  55                  60                  


Leu Asn Gly Thr Phe Pro Asn Thr Ser Asp Ala Asp Met Glu Pro Cys 
65                  70                  75                  80  


Val Asp Gly Trp Val Tyr Asp Arg Ile Ser Phe Ser Ser Thr Ile Val 
                85                  90                  95      


Thr Glu Trp Asp Leu Val Cys Asp Ser Gln Ser 
            100                 105         


<210>  2627
<211>  244
<212>  PRT
<213>  Homo Sapiens

<400>  2627

Gly Cys Ala Glu Ala Gly Arg Cys Cys Pro Gly Arg Asp Pro Ala Cys 
1               5                   10                  15      


Phe Ala Arg Gly Trp Arg Leu Asp Arg Val Tyr Gly Thr Cys Phe Cys 
            20                  25                  30          


Asp Gln Ala Cys Arg Phe Thr Gly Asp Cys Cys Phe Asp Tyr Asp Arg 
        35                  40                  45              


Ala Cys Pro Ala Arg Pro Cys Phe Val Gly Glu Trp Ser Pro Trp Ser 
    50                  55                  60                  


Gly Cys Ala Asp Gln Cys Lys Pro Thr Thr Arg Val Arg Arg Arg Ser 
65                  70                  75                  80  


Val Gln Gln Glu Pro Gln Asn Gly Gly Ala Pro Cys Pro Pro Leu Glu 
                85                  90                  95      


Glu Arg Ala Gly Cys Leu Glu Tyr Ser Thr Pro Gln Gly Gln Asp Cys 
            100                 105                 110         


Gly His Thr Tyr Val Pro Ala Phe Ile Thr Thr Ser Ala Phe Asn Lys 
        115                 120                 125             


Glu Arg Thr Arg Gln Ala Thr Ser Pro His Trp Ser Thr His Thr Glu 
    130                 135                 140                 


Asp Ala Gly Tyr Cys Met Glu Phe Lys Thr Glu Ser Leu Thr Pro His 
145                 150                 155                 160 


Cys Ala Leu Glu Asn Trp Pro Leu Thr Arg Trp Met Gln Tyr Leu Arg 
                165                 170                 175     


Glu Gly Tyr Thr Val Cys Val Asp Cys Gln Pro Pro Ala Met Asn Ser 
            180                 185                 190         


Val Ser Leu Arg Cys Ser Gly Asp Gly Leu Asp Ser Asp Gly Asn Gln 
        195                 200                 205             


Thr Leu His Trp Gln Ala Ile Gly Asn Pro Arg Cys Gln Gly Thr Trp 
    210                 215                 220                 


Lys Lys Val Arg Arg Val Asp Gln Cys Ser Cys Pro Ala Val His Ser 
225                 230                 235                 240 


Phe Ile Phe Ile 
                


<210>  2628
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  2628

Leu Lys Pro Ser Phe Ser Pro Arg Asn Tyr Lys Ala Leu Ser Glu Val 
1               5                   10                  15      


Gln Gly Trp Lys Gln Arg Met Ala Ala Lys Glu Leu Ala Arg Gln Asn 
            20                  25                  30          


Met Asp Leu Gly Phe Lys Leu Leu Lys Lys Leu Ala Phe Tyr Asn Pro 
        35                  40                  45              


Gly Arg Asn Ile Phe Leu Ser Pro Leu Ser Ile Ser Thr Ala Phe Ser 
    50                  55                  60                  


Met Leu Cys Leu Gly Ala Gln Asp Ser Thr Leu Asp Glu Ile Lys Gln 
65                  70                  75                  80  


Gly Phe Asn Phe Arg Lys Met Pro Glu Lys Asp Leu His Glu Gly Phe 
                85                  90                  95      


His Tyr Ile Ile His Glu Leu Thr Gln Lys Thr Gln Asp Leu Lys Leu 
            100                 105                 110         


Ser Ile Gly Asn Thr Leu Phe Ile Asp Gln Arg Leu Gln Pro Gln Arg 
        115                 120                 125             


Lys Phe Leu Glu Asp Ala Lys Asn Phe Tyr Ser Ala Glu Thr Ile Leu 
    130                 135                 140                 


Thr Asn Phe Gln Asn Leu Glu Met Ala Gln Lys Gln Ile Asn Asp Phe 
145                 150                 155                 160 


Ile Ser Gln Lys Thr His Gly Lys Ile Asn Asn Leu Ile Glu Asn Ile 
                165                 170                 175     


Asp Pro Gly Thr Val Met Leu Leu Ala Asn Tyr Ile Phe Phe Arg Ala 
            180                 185                 190         


Arg Trp Lys His Glu Phe Asp Pro Asn Val Thr Lys Glu Glu Asp Phe 
        195                 200                 205             


Phe Leu Glu Lys Asn Ser Ser Val Lys Val Pro Met Met Phe Arg Ser 
    210                 215                 220                 


Gly Ile Tyr Gln Val Gly Tyr Asp Asp Lys Leu Ser Cys Thr Ile Leu 
225                 230                 235                 240 


Glu Ile Pro Tyr Gln Lys Asn Ile Thr Ala Ile Phe Ile Leu Pro Asp 
                245                 250                 255     


Glu Gly Lys Leu Lys His Leu Glu Lys Gly Leu Gln Val Asp Thr Phe 
            260                 265                 270         


Ser Arg Trp Lys Thr Leu Leu Ser Arg Arg Val Val Asp Val Ser Val 
        275                 280                 285             


Pro Arg Leu His Met Thr Gly Thr Phe Asp Leu Lys Lys Thr Leu Ser 
    290                 295                 300                 


Tyr Ile Gly Val Ser Lys Ile Phe Glu Glu His Gly Asp Leu Thr Lys 
305                 310                 315                 320 


Ile Ala Pro His Arg Ser Leu Lys Val Gly Glu Ala Val His Lys Ala 
                325                 330                 335     


Glu Leu Lys Met Asp Glu Arg Gly Thr Glu Gly Ala Ala Gly Thr Gly 
            340                 345                 350         


Ala Gln Thr Leu Pro Met Glu Thr Pro Leu Val Val Lys Ile Asp Lys 
        355                 360                 365             


Pro Tyr Leu Leu Leu Ile Tyr Ser Glu Lys Ile Pro Ser Val Leu Phe 
    370                 375                 380                 


Leu Gly Lys Ile Val Asn Pro Ile Gly Lys 
385                 390                 


<210>  2629
<211>  604
<212>  PRT
<213>  Homo Sapiens

<400>  2629

Ser Thr Leu Val Pro Leu Arg Leu Arg His Arg Gln Leu Gly Leu Gln 
1               5                   10                  15      


Ala Lys Gly Trp Asn Phe Met Leu Glu Asp Ser Thr Phe Trp Ile Phe 
            20                  25                  30          


Gly Gly Ser Ile His Tyr Phe Arg Val Pro Arg Glu Tyr Trp Arg Asp 
        35                  40                  45              


Arg Leu Leu Lys Met Lys Ala Cys Gly Leu Asn Thr Leu Thr Thr Tyr 
    50                  55                  60                  


Val Pro Trp Asn Leu His Glu Pro Glu Arg Gly Lys Phe Asp Phe Ser 
65                  70                  75                  80  


Gly Asn Leu Asp Leu Glu Ala Phe Val Leu Met Ala Ala Glu Ile Gly 
                85                  90                  95      


Leu Trp Val Ile Leu Arg Pro Gly Pro Tyr Ile Cys Ser Glu Met Asp 
            100                 105                 110         


Leu Gly Gly Leu Pro Ser Trp Leu Leu Gln Asp Pro Gly Met Arg Leu 
        115                 120                 125             


Arg Thr Thr Tyr Lys Gly Phe Thr Glu Ala Val Asp Leu Tyr Phe Asp 
    130                 135                 140                 


His Leu Met Ser Arg Val Val Pro Leu Gln Tyr Lys Arg Gly Gly Pro 
145                 150                 155                 160 


Ile Ile Ala Val Gln Val Glu Asn Glu Tyr Gly Ser Tyr Asn Lys Asp 
                165                 170                 175     


Pro Ala Tyr Met Pro Tyr Val Lys Lys Ala Leu Glu Asp Arg Gly Ile 
            180                 185                 190         


Val Glu Leu Leu Leu Thr Ser Asp Asn Lys Asp Gly Leu Ser Lys Gly 
        195                 200                 205             


Ile Val Gln Gly Val Leu Ala Thr Ile Asn Leu Gln Ser Thr His Glu 
    210                 215                 220                 


Leu Gln Leu Leu Thr Thr Phe Leu Phe Asn Val Gln Gly Thr Gln Pro 
225                 230                 235                 240 


Lys Met Val Met Glu Tyr Trp Thr Gly Trp Phe Asp Ser Trp Gly Gly 
                245                 250                 255     


Pro His Asn Ile Leu Asp Ser Ser Glu Val Leu Lys Thr Val Ser Ala 
            260                 265                 270         


Ile Val Asp Ala Gly Ser Ser Ile Asn Leu Tyr Met Phe His Gly Gly 
        275                 280                 285             


Thr Asn Phe Gly Phe Met Asn Gly Ala Met His Phe His Asp Tyr Lys 
    290                 295                 300                 


Ser Asp Val Thr Ser Tyr Asp Tyr Asp Ala Val Leu Thr Glu Ala Gly 
305                 310                 315                 320 


Asp Tyr Thr Ala Lys Tyr Met Lys Leu Arg Asp Phe Phe Gly Ser Ile 
                325                 330                 335     


Ser Gly Ile Pro Leu Pro Pro Pro Pro Asp Leu Leu Pro Lys Met Pro 
            340                 345                 350         


Tyr Glu Pro Leu Thr Pro Val Leu Tyr Leu Ser Leu Trp Asp Ala Leu 
        355                 360                 365             


Lys Tyr Leu Gly Glu Pro Ile Lys Ser Glu Lys Pro Ile Asn Met Glu 
    370                 375                 380                 


Asn Leu Pro Val Asn Gly Gly Asn Gly Gln Ser Phe Gly Tyr Ile Leu 
385                 390                 395                 400 


Tyr Glu Thr Ser Ile Thr Ser Ser Gly Ile Leu Ser Gly His Val His 
                405                 410                 415     


Asp Arg Gly Gln Val Phe Val Asn Thr Val Ser Ile Gly Phe Leu Asp 
            420                 425                 430         


Tyr Lys Thr Thr Lys Ile Ala Val Pro Leu Ile Gln Gly Tyr Thr Val 
        435                 440                 445             


Leu Arg Ile Leu Val Glu Asn Arg Gly Arg Val Asn Tyr Gly Glu Asn 
    450                 455                 460                 


Ile Asp Asp Gln Arg Lys Gly Leu Ile Gly Asn Leu Tyr Leu Asn Asp 
465                 470                 475                 480 


Ser Pro Leu Lys Asn Phe Arg Ile Tyr Ser Leu Asp Met Lys Lys Ser 
                485                 490                 495     


Phe Phe Gln Arg Phe Gly Leu Asp Lys Trp Ser Ser Leu Pro Glu Thr 
            500                 505                 510         


Pro Thr Leu Pro Ala Phe Phe Leu Gly Ser Leu Ser Ile Ser Ser Thr 
        515                 520                 525             


Pro Cys Asp Thr Phe Leu Lys Leu Glu Gly Trp Glu Lys Gly Val Val 
    530                 535                 540                 


Phe Ile Asn Gly Gln Asn Leu Gly Arg Tyr Trp Asn Ile Gly Pro Gln 
545                 550                 555                 560 


Lys Thr Leu Tyr Leu Pro Gly Pro Trp Leu Ser Ser Gly Ile Asn Gln 
                565                 570                 575     


Val Ile Val Phe Glu Glu Thr Met Ala Gly Pro Ala Leu Gln Phe Thr 
            580                 585                 590         


Glu Thr Pro His Leu Gly Arg Asn Gln Tyr Ile Lys 
        595                 600                 


<210>  2630
<211>  658
<212>  PRT
<213>  Homo Sapiens

<400>  2630

Val Pro Pro Arg Arg Asp Tyr Cys Val Leu Gly Ala Gly Pro Ala Gly 
1               5                   10                  15      


Leu Gln Met Ala Tyr Phe Leu Gln Arg Ala Gly Arg Asp Tyr Ala Val 
            20                  25                  30          


Phe Glu Arg Ala Pro Arg Pro Gly Ser Phe Phe Thr Arg Tyr Pro Arg 
        35                  40                  45              


His Arg Lys Leu Ile Ser Ile Asn Lys Arg Tyr Thr Gly Lys Ala Asn 
    50                  55                  60                  


Ala Glu Phe Asn Leu Arg His Asp Trp Asn Ser Leu Leu Ser His Asp 
65                  70                  75                  80  


Pro Arg Leu Leu Phe Arg His Tyr Ser Arg Ala Tyr Phe Pro Asp Ala 
                85                  90                  95      


Arg Asp Met Val Arg Tyr Leu Gly Asp Phe Ala Asp Thr Leu Gly Leu 
            100                 105                 110         


Arg Val Gln Tyr Asn Thr Thr Ile Ala His Val Thr Leu Asp Lys Asp 
        115                 120                 125             


Arg Gln Ala Trp Asn Gly His Tyr Phe Ile Leu Thr Asp Gln Lys Gly 
    130                 135                 140                 


Gln Val His Gln Cys Ser Val Leu Phe Val Ala Thr Gly Leu Ser Val 
145                 150                 155                 160 


Pro Asn Gln Val Asp Phe Pro Gly Ser Glu Tyr Ala Glu Gly Tyr Glu 
                165                 170                 175     


Ser Val Ser Val Asp Pro Glu Asp Phe Val Gly Gln Asn Val Leu Ile 
            180                 185                 190         


Leu Gly Arg Gly Asn Ser Ala Phe Glu Thr Ala Glu Asn Ile Leu Gly 
        195                 200                 205             


Val Thr Asn Phe Ile His Met Leu Ser Arg Ser Arg Val Arg Leu Ser 
    210                 215                 220                 


Trp Ala Thr His Tyr Val Gly Asp Leu Arg Ala Ile Asn Asn Gly Leu 
225                 230                 235                 240 


Leu Asp Thr Tyr Gln Leu Lys Ser Leu Asp Gly Leu Leu Glu Ser Asp 
                245                 250                 255     


Leu Thr Asp Leu Ala Ile Leu Lys Asp Ser Lys Gly Lys Phe His Val 
            260                 265                 270         


Thr Pro Lys Phe Phe Leu Glu Glu Ala Asn Thr Asn Gln Ser Ala Asp 
        275                 280                 285             


Ser Ile Thr Leu Pro Gln Asp Asp Asn Asp Asn Phe Ala Met Arg Val 
    290                 295                 300                 


Pro Tyr Asp Arg Val Ile Arg Cys Leu Gly Trp Asn Phe Asp Phe Ser 
305                 310                 315                 320 


Ile Phe Asn Lys Ser Leu Arg Leu Asn Ser Gly Asn Ala Phe Gly Lys 
                325                 330                 335     


Lys Tyr Pro Leu Ile Arg Ala Ser Tyr Glu Ser Lys Gly Ser Arg Gly 
            340                 345                 350         


Leu Phe Ile Leu Gly Thr Ala Ser His Ser Val Asp Tyr Arg Lys Ser 
        355                 360                 365             


Ala Gly Gly Phe Ile His Gly Phe Arg Tyr Thr Val Arg Ala Val His 
    370                 375                 380                 


Arg Leu Leu Glu His Arg His His Ser Val Thr Trp Pro Ala Thr Glu 
385                 390                 395                 400 


Leu Pro Ile Thr Gln Leu Thr Ser Ser Ile Val Arg Arg Val Asn Glu 
                405                 410                 415     


Ala Ser Gly Leu Tyr Gln Met Phe Gly Val Leu Ala Asp Val Ile Leu 
            420                 425                 430         


Leu Lys Glu Asn Ser Thr Ala Phe Glu Tyr Leu Glu Glu Phe Pro Ile 
        435                 440                 445             


Gln Met Leu Ala Gln Leu Glu Thr Leu Thr Gly Arg Lys Ala Lys His 
    450                 455                 460                 


Gly Leu Phe Val Ile Asn Met Glu Tyr Gly Arg Asn Phe Ser Gly Pro 
465                 470                 475                 480 


Asp Lys Asp Val Phe Phe Asp Asp Arg Ser Val Gly His Thr Glu Asp 
                485                 490                 495     


Ala Trp Gln Ser Asn Phe Leu His Pro Val Ile Tyr Tyr Tyr Arg Tyr 
            500                 505                 510         


Leu Pro Thr Glu Gln Glu Val Arg Phe Arg Pro Ala His Trp Pro Leu 
        515                 520                 525             


Pro Arg Pro Thr Ala Ile His His Ile Val Glu Asp Phe Leu Thr Asp 
    530                 535                 540                 


Trp Thr Ala Pro Ile Gly His Ile Leu Pro Leu Arg Arg Phe Leu Glu 
545                 550                 555                 560 


Asn Cys Leu Asp Thr Asp Leu Arg Ser Phe Tyr Ala Glu Ser Cys Phe 
                565                 570                 575     


Leu Phe Ala Leu Thr Arg Gln Lys Leu Pro Pro Phe Cys Gln Gln Gly 
            580                 585                 590         


Tyr Leu Arg Met Gln Gly Leu Val Ser Thr Glu Ser Leu Trp Gln His 
        595                 600                 605             


Arg Val Glu Ser Arg Leu Leu Arg Asp Tyr Ala Pro Thr Gly Arg Arg 
    610                 615                 620                 


Leu Glu Asp Ser Ser Gln Gln Leu Gly Asp Gln Glu Pro Leu Gly Ser 
625                 630                 635                 640 


Pro Leu Ala Pro Gly Pro Leu Ala Gln Ser Val Asp Ser Asn Lys Glu 
                645                 650                 655     


Glu Leu 
        


<210>  2631
<211>  846
<212>  PRT
<213>  Homo Sapiens

<400>  2631

Phe Leu Ser His His Arg Leu Lys Gly Arg Phe Gln Arg Asp Arg Arg 
1               5                   10                  15      


Asn Ile Arg Pro Asn Ile Ile Leu Val Leu Thr Asp Asp Gln Asp Val 
            20                  25                  30          


Glu Leu Gly Ser Met Gln Val Met Asn Lys Thr Arg Arg Ile Met Glu 
        35                  40                  45              


Gln Gly Gly Ala His Phe Ile Asn Ala Phe Val Thr Thr Pro Met Cys 
    50                  55                  60                  


Cys Pro Ser Arg Ser Ser Ile Leu Thr Gly Lys Tyr Val His Asn His 
65                  70                  75                  80  


Asn Thr Tyr Thr Asn Asn Glu Asn Cys Ser Ser Pro Ser Trp Gln Ala 
                85                  90                  95      


Gln His Glu Ser Arg Thr Phe Ala Val Tyr Leu Asn Ser Thr Gly Tyr 
            100                 105                 110         


Arg Thr Ala Phe Phe Gly Lys Tyr Leu Asn Glu Tyr Asn Gly Ser Tyr 
        115                 120                 125             


Val Pro Pro Gly Trp Lys Glu Trp Val Gly Leu Leu Lys Asn Ser Arg 
    130                 135                 140                 


Phe Tyr Asn Tyr Thr Leu Cys Arg Asn Gly Val Lys Glu Lys His Gly 
145                 150                 155                 160 


Ser Asp Tyr Ser Lys Asp Tyr Leu Thr Asp Leu Ile Thr Asn Asp Ser 
                165                 170                 175     


Val Ser Phe Phe Arg Thr Ser Lys Lys Met Tyr Pro His Arg Pro Val 
            180                 185                 190         


Leu Met Val Ile Ser His Ala Ala Pro His Gly Pro Glu Asp Ser Ala 
        195                 200                 205             


Pro Gln Tyr Ser Arg Leu Phe Pro Asn Ala Ser Gln His Ile Thr Pro 
    210                 215                 220                 


Ser Tyr Asn Tyr Ala Pro Asn Pro Asp Lys His Trp Ile Met Arg Tyr 
225                 230                 235                 240 


Thr Gly Pro Met Lys Pro Ile His Met Glu Phe Thr Asn Met Leu Gln 
                245                 250                 255     


Arg Lys Arg Leu Gln Thr Leu Met Ser Val Asp Asp Ser Met Glu Thr 
            260                 265                 270         


Ile Tyr Asn Met Leu Val Glu Thr Gly Glu Leu Asp Asn Thr Tyr Ile 
        275                 280                 285             


Val Tyr Thr Ala Asp His Gly Tyr His Ile Gly Gln Phe Gly Leu Val 
    290                 295                 300                 


Lys Gly Lys Ser Met Pro Tyr Glu Phe Asp Ile Arg Val Pro Phe Tyr 
305                 310                 315                 320 


Val Arg Gly Pro Asn Val Glu Ala Gly Cys Leu Asn Pro His Ile Val 
                325                 330                 335     


Leu Asn Ile Asp Leu Ala Pro Thr Ile Leu Asp Ile Ala Gly Leu Asp 
            340                 345                 350         


Ile Pro Ala Asp Met Asp Gly Lys Ser Ile Leu Lys Leu Leu Asp Thr 
        355                 360                 365             


Glu Arg Pro Val Asn Arg Phe His Leu Lys Lys Lys Met Arg Val Trp 
    370                 375                 380                 


Arg Asp Ser Phe Leu Val Glu Arg Gly Lys Leu Leu His Lys Arg Asp 
385                 390                 395                 400 


Asn Asp Lys Val Asp Ala Gln Glu Glu Asn Phe Leu Pro Lys Tyr Gln 
                405                 410                 415     


Arg Val Lys Asp Leu Cys Gln Arg Ala Glu Tyr Gln Thr Ala Cys Glu 
            420                 425                 430         


Gln Leu Gly Gln Lys Trp Gln Cys Val Glu Asp Ala Thr Gly Lys Leu 
        435                 440                 445             


Lys Leu His Lys Cys Lys Gly Pro Met Arg Leu Gly Gly Ser Arg Ala 
    450                 455                 460                 


Leu Ser Asn Leu Val Pro Lys Tyr Tyr Gly Gln Gly Ser Glu Ala Cys 
465                 470                 475                 480 


Thr Cys Asp Ser Gly Asp Tyr Lys Leu Ser Leu Ala Gly Arg Arg Lys 
                485                 490                 495     


Lys Leu Phe Lys Lys Lys Tyr Lys Ala Ser Tyr Val Arg Ser Arg Ser 
            500                 505                 510         


Ile Arg Ser Val Ala Ile Glu Val Asp Gly Arg Val Tyr His Val Gly 
        515                 520                 525             


Leu Gly Asp Ala Ala Gln Pro Arg Asn Leu Thr Lys Arg His Trp Pro 
    530                 535                 540                 


Gly Ala Pro Glu Asp Gln Asp Asp Lys Asp Gly Gly Asp Phe Ser Gly 
545                 550                 555                 560 


Thr Gly Gly Leu Pro Asp Tyr Ser Ala Ala Asn Pro Ile Lys Val Thr 
                565                 570                 575     


His Arg Cys Tyr Ile Leu Glu Asn Asp Thr Val Gln Cys Asp Leu Asp 
            580                 585                 590         


Leu Tyr Lys Ser Leu Gln Ala Trp Lys Asp His Lys Leu His Ile Asp 
        595                 600                 605             


His Glu Ile Glu Thr Leu Gln Asn Lys Ile Lys Asn Leu Arg Glu Val 
    610                 615                 620                 


Arg Gly His Leu Lys Lys Lys Arg Pro Glu Glu Cys Asp Cys His Lys 
625                 630                 635                 640 


Ile Ser Tyr His Thr Gln His Lys Gly Arg Leu Lys His Arg Gly Ser 
                645                 650                 655     


Ser Leu His Pro Phe Arg Lys Gly Leu Gln Glu Lys Asp Lys Val Trp 
            660                 665                 670         


Leu Leu Arg Glu Gln Lys Arg Lys Lys Lys Leu Arg Lys Leu Leu Lys 
        675                 680                 685             


Arg Leu Gln Asn Asn Asp Thr Cys Ser Met Pro Gly Leu Thr Cys Phe 
    690                 695                 700                 


Thr His Asp Asn Gln His Trp Gln Thr Ala Pro Phe Trp Thr Leu Gly 
705                 710                 715                 720 


Pro Phe Cys Ala Cys Thr Ser Ala Asn Asn Asn Thr Tyr Trp Cys Met 
                725                 730                 735     


Arg Thr Ile Asn Glu Thr His Asn Phe Leu Phe Cys Glu Phe Ala Thr 
            740                 745                 750         


Gly Phe Leu Glu Tyr Phe Asp Leu Asn Thr Asp Pro Tyr Gln Leu Met 
        755                 760                 765             


Asn Ala Val Asn Thr Leu Asp Arg Asp Val Leu Asn Gln Leu His Val 
    770                 775                 780                 


Gln Leu Met Glu Leu Arg Ser Cys Lys Gly Tyr Lys Gln Cys Asn Pro 
785                 790                 795                 800 


Arg Thr Arg Asn Met Asp Leu Gly Leu Lys Asp Gly Gly Ser Tyr Glu 
                805                 810                 815     


Gln Tyr Arg Gln Phe Gln Arg Arg Lys Trp Pro Glu Met Lys Arg Pro 
            820                 825                 830         


Ser Ser Lys Ser Leu Gly Gln Leu Trp Glu Gly Trp Glu Gly 
        835                 840                 845     


<210>  2632
<211>  849
<212>  PRT
<213>  Homo Sapiens

<400>  2632

Ser Thr Val Arg Ser Pro Arg Phe Arg Gly Arg Ile Gln Gln Glu Arg 
1               5                   10                  15      


Lys Asn Ile Arg Pro Asn Ile Ile Leu Val Leu Thr Asp Asp Gln Asp 
            20                  25                  30          


Val Glu Leu Gly Ser Leu Gln Val Met Asn Lys Thr Arg Lys Ile Met 
        35                  40                  45              


Glu His Gly Gly Ala Thr Phe Ile Asn Ala Phe Val Thr Thr Pro Met 
    50                  55                  60                  


Cys Cys Pro Ser Arg Ser Ser Met Leu Thr Gly Lys Tyr Val His Asn 
65                  70                  75                  80  


His Asn Val Tyr Thr Asn Asn Glu Asn Cys Ser Ser Pro Ser Trp Gln 
                85                  90                  95      


Ala Met His Glu Pro Arg Thr Phe Ala Val Tyr Leu Asn Asn Thr Gly 
            100                 105                 110         


Tyr Arg Thr Val Phe Phe Gly Lys Tyr Leu Asn Glu Tyr Asn Gly Ser 
        115                 120                 125             


Tyr Ile Pro Pro Gly Trp Arg Glu Trp Leu Gly Leu Ile Lys Asn Ser 
    130                 135                 140                 


Arg Phe Tyr Asn Tyr Thr Val Cys Arg Asn Gly Ile Lys Glu Lys His 
145                 150                 155                 160 


Gly Phe Asp Tyr Ala Lys Asp Tyr Phe Thr Asp Leu Ile Thr Asn Glu 
                165                 170                 175     


Ser Ile Asn Tyr Phe Lys Met Ser Lys Arg Met Tyr Pro His Arg Pro 
            180                 185                 190         


Val Met Met Val Ile Ser His Ala Ala Pro His Gly Pro Glu Asp Ser 
        195                 200                 205             


Ala Pro Gln Phe Ser Lys Leu Tyr Pro Asn Ala Ser Gln His Ile Thr 
    210                 215                 220                 


Pro Ser Tyr Asn Tyr Ala Pro Asn Met Asp Lys His Trp Ile Met Gln 
225                 230                 235                 240 


Tyr Thr Gly Pro Met Leu Pro Ile His Met Glu Phe Thr Asn Ile Leu 
                245                 250                 255     


Gln Arg Lys Arg Leu Gln Thr Leu Met Ser Val Asp Asp Ser Val Glu 
            260                 265                 270         


Arg Leu Tyr Asn Met Leu Val Glu Thr Gly Glu Leu Glu Asn Thr Tyr 
        275                 280                 285             


Ile Ile Tyr Thr Ala Asp His Gly Tyr His Ile Gly Gln Phe Gly Leu 
    290                 295                 300                 


Val Lys Gly Lys Ser Met Pro Tyr Asp Phe Asp Ile Arg Val Pro Phe 
305                 310                 315                 320 


Phe Ile Arg Gly Pro Ser Val Glu Pro Gly Ser Ile Val Pro Gln Ile 
                325                 330                 335     


Val Leu Asn Ile Asp Leu Ala Pro Thr Ile Leu Asp Ile Ala Gly Leu 
            340                 345                 350         


Asp Thr Pro Pro Asp Val Asp Gly Lys Ser Val Leu Lys Leu Leu Asp 
        355                 360                 365             


Pro Glu Lys Pro Gly Asn Arg Phe Arg Thr Asn Lys Lys Ala Lys Ile 
    370                 375                 380                 


Trp Arg Asp Thr Phe Leu Val Glu Arg Gly Lys Phe Leu Arg Lys Lys 
385                 390                 395                 400 


Glu Glu Ser Ser Lys Asn Ile Gln Gln Ser Asn His Leu Pro Lys Tyr 
                405                 410                 415     


Glu Arg Val Lys Glu Leu Cys Gln Gln Ala Arg Tyr Gln Thr Ala Cys 
            420                 425                 430         


Glu Gln Pro Gly Gln Lys Trp Gln Cys Ile Glu Asp Thr Ser Gly Lys 
        435                 440                 445             


Leu Arg Ile His Lys Cys Lys Gly Pro Ser Asp Leu Leu Thr Val Arg 
    450                 455                 460                 


Gln Ser Thr Arg Asn Leu Tyr Ala Arg Gly Phe His Asp Lys Asp Lys 
465                 470                 475                 480 


Glu Cys Ser Cys Arg Glu Ser Gly Tyr Arg Ala Ser Arg Ser Gln Arg 
                485                 490                 495     


Lys Ser Gln Arg Gln Phe Leu Arg Asn Gln Gly Thr Pro Lys Tyr Lys 
            500                 505                 510         


Pro Arg Phe Val His Thr Arg Gln Thr Arg Ser Leu Ser Val Glu Phe 
        515                 520                 525             


Glu Gly Glu Ile Tyr Asp Ile Asn Leu Glu Glu Glu Glu Glu Leu Gln 
    530                 535                 540                 


Val Leu Gln Pro Arg Asn Ile Ala Lys Arg His Asp Glu Gly His Lys 
545                 550                 555                 560 


Gly Pro Arg Asp Leu Gln Ala Ser Ser Gly Gly Asn Arg Gly Arg Met 
                565                 570                 575     


Leu Ala Asp Ser Ser Asn Ala Val Gly Pro Pro Thr Thr Val Arg Val 
            580                 585                 590         


Thr His Lys Cys Phe Ile Leu Pro Asn Asp Ser Ile His Cys Glu Arg 
        595                 600                 605             


Glu Leu Tyr Gln Ser Ala Arg Ala Trp Lys Asp His Lys Ala Tyr Ile 
    610                 615                 620                 


Asp Lys Glu Ile Glu Ala Leu Gln Asp Lys Ile Lys Asn Leu Arg Glu 
625                 630                 635                 640 


Val Arg Gly His Leu Lys Arg Arg Lys Pro Glu Glu Cys Ser Cys Ser 
                645                 650                 655     


Lys Gln Ser Tyr Tyr Asn Lys Glu Lys Gly Val Lys Lys Gln Glu Lys 
            660                 665                 670         


Leu Lys Ser His Leu His Pro Phe Lys Glu Ala Ala Gln Glu Val Asp 
        675                 680                 685             


Ser Lys Leu Gln Leu Phe Lys Glu Asn Asn Arg Arg Arg Lys Lys Glu 
    690                 695                 700                 


Arg Lys Glu Lys Arg Arg Gln Arg Lys Gly Glu Glu Cys Ser Leu Pro 
705                 710                 715                 720 


Gly Leu Thr Cys Phe Thr His Asp Asn Asn His Trp Gln Thr Ala Pro 
                725                 730                 735     


Phe Trp Asn Leu Gly Ser Phe Cys Ala Cys Thr Ser Ser Asn Asn Asn 
            740                 745                 750         


Thr Tyr Trp Cys Leu Arg Thr Val Asn Glu Thr His Asn Phe Leu Phe 
        755                 760                 765             


Cys Glu Phe Ala Thr Gly Phe Leu Glu Tyr Phe Asp Met Asn Thr Asp 
    770                 775                 780                 


Pro Tyr Gln Leu Thr Asn Thr Val His Thr Val Glu Arg Gly Ile Leu 
785                 790                 795                 800 


Asn Gln Leu His Val Gln Leu Met Glu Leu Arg Ser Cys Gln Gly Tyr 
                805                 810                 815     


Lys Gln Cys Asn Pro Arg Pro Lys Asn Leu Asp Val Gly Asn Lys Asp 
            820                 825                 830         


Gly Gly Ser Tyr Asp Leu His Arg Gly Gln Leu Trp Asp Gly Trp Glu 
        835                 840                 845             


Gly 
    


<210>  2633
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  2633

Lys Asn Ala Glu Met Ser Lys Glu Leu Leu Gly Phe Lys Arg Glu Leu 
1               5                   10                  15      


Trp Asn Val Ser Asn Ser Val Gln Ala Cys Glu Glu Arg Gln Lys Arg 
            20                  25                  30          


Gly Trp Asp Ser Val Gln Gln Ser Ile Thr Met Val Arg Ser Lys Ile 
        35                  40                  45              


Asp Arg Leu Glu Thr Thr Leu Ala Gly Ile Lys Asn Ile Asp Thr Lys 
    50                  55                  60                  


Val Gln Lys Ile Leu Glu Val Leu Gln Lys Met Pro Gln Ser Ser Pro 
65                  70                  75                  80  


Gln 
    


<210>  2634
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  2634

Ser Glu Ala Lys Leu Tyr Gly Arg Cys Glu Leu Ala Arg Val Leu His 
1               5                   10                  15      


Asp Phe Gly Leu Asp Gly Tyr Arg Gly Tyr Ser Leu Ala Asp Trp Val 
            20                  25                  30          


Cys Leu Ala Tyr Phe Thr Ser Gly Phe Asn Ala Ala Ala Leu Asp Tyr 
        35                  40                  45              


Glu Ala Asp Gly Ser Thr Asn Asn Gly Ile Phe Gln Ile Asn Ser Arg 
    50                  55                  60                  


Arg Trp Cys Ser Asn Leu Thr Pro Asn Val Pro Asn Val Cys Arg Met 
65                  70                  75                  80  


Tyr Cys Ser Asp Leu Leu Asn Pro Asn Leu Lys Asp Thr Val Ile Cys 
                85                  90                  95      


Ala Met Lys Ile Thr Gln Glu Pro Gln Gly Leu Gly Tyr Trp Glu Ala 
            100                 105                 110         


Trp Arg His His Cys Gln Gly Lys Asp Leu Thr Glu Trp Val Asp Gly 
        115                 120                 125             


Cys Asp Phe 
    130     


<210>  2635
<211>  761
<212>  PRT
<213>  Homo Sapiens

<400>  2635

Asp Gln Asp Phe Tyr Ser Leu Leu Gly Val Ser Lys Thr Ala Ser Ser 
1               5                   10                  15      


Arg Glu Ile Arg Gln Ala Phe Lys Lys Leu Ala Leu Lys Leu His Pro 
            20                  25                  30          


Asp Lys Asn Pro Asn Asn Pro Asn Ala His Gly Asp Phe Leu Lys Ile 
        35                  40                  45              


Asn Arg Ala Tyr Glu Val Leu Lys Asp Glu Asp Leu Arg Lys Lys Tyr 
    50                  55                  60                  


Asp Lys Tyr Gly Glu Lys Gly Leu Glu Asp Asn Gln Gly Gly Gln Tyr 
65                  70                  75                  80  


Glu Ser Trp Asn Tyr Tyr Arg Tyr Asp Phe Gly Ile Tyr Asp Asp Asp 
                85                  90                  95      


Pro Glu Ile Ile Thr Leu Glu Arg Arg Glu Phe Asp Ala Ala Val Asn 
            100                 105                 110         


Ser Gly Glu Leu Trp Phe Val Asn Phe Tyr Ser Pro Gly Cys Ser His 
        115                 120                 125             


Cys His Asp Leu Ala Pro Thr Trp Arg Asp Phe Ala Lys Glu Val Asp 
    130                 135                 140                 


Gly Leu Leu Arg Ile Gly Ala Val Asn Cys Gly Asp Asp Arg Met Leu 
145                 150                 155                 160 


Cys Arg Met Lys Gly Val Asn Ser Tyr Pro Ser Leu Phe Ile Phe Arg 
                165                 170                 175     


Ser Gly Met Ala Pro Val Lys Tyr His Gly Asp Arg Ser Lys Glu Ser 
            180                 185                 190         


Leu Val Ser Phe Ala Met Gln His Val Arg Ser Thr Val Thr Glu Leu 
        195                 200                 205             


Trp Thr Gly Asn Phe Val Asn Ser Ile Gln Thr Ala Phe Ala Ala Gly 
    210                 215                 220                 


Ile Gly Trp Leu Ile Thr Phe Cys Ser Lys Gly Gly Asp Cys Leu Thr 
225                 230                 235                 240 


Ser Gln Thr Arg Leu Arg Leu Ser Gly Met Leu Asp Gly Leu Val Asn 
                245                 250                 255     


Val Gly Trp Met Asp Cys Ala Thr Gln Asp Asn Leu Cys Lys Ser Leu 
            260                 265                 270         


Asp Ile Thr Thr Ser Thr Thr Ala Tyr Phe Pro Pro Gly Ala Thr Leu 
        275                 280                 285             


Asn Asn Lys Glu Lys Asn Ser Ile Leu Phe Leu Asn Ser Leu Asp Ala 
    290                 295                 300                 


Lys Glu Ile Tyr Leu Glu Val Ile His Asn Leu Pro Asp Phe Glu Leu 
305                 310                 315                 320 


Leu Ser Ala Asn Thr Leu Glu Asp Arg Leu Ala His His Arg Trp Leu 
                325                 330                 335     


Leu Phe Phe His Phe Gly Lys Asn Glu Asn Ser Asn Asp Pro Glu Leu 
            340                 345                 350         


Lys Lys Leu Lys Thr Leu Leu Lys Asn Asp His Ile Gln Val Gly Arg 
        355                 360                 365             


Phe Asp Cys Ser Ser Ala Pro Asp Ile Cys Ser Asn Leu Tyr Val Phe 
    370                 375                 380                 


Gln Pro Ser Leu Ala Val Phe Lys Gly Gln Gly Thr Lys Glu Tyr Glu 
385                 390                 395                 400 


Ile His His Gly Lys Lys Ile Leu Tyr Asp Ile Leu Ala Phe Ala Lys 
                405                 410                 415     


Glu Ser Val Asn Ser His Val Thr Thr Leu Gly Pro Gln Asn Phe Pro 
            420                 425                 430         


Ala Asn Asp Lys Glu Pro Trp Leu Val Asp Phe Phe Ala Pro Trp Cys 
        435                 440                 445             


Pro Pro Cys Arg Ala Leu Leu Pro Glu Leu Arg Arg Ala Ser Asn Leu 
    450                 455                 460                 


Leu Tyr Gly Gln Leu Lys Phe Gly Thr Leu Asp Cys Thr Val His Glu 
465                 470                 475                 480 


Gly Leu Cys Asn Met Tyr Asn Ile Gln Ala Tyr Pro Thr Thr Val Val 
                485                 490                 495     


Phe Asn Gln Ser Asn Ile His Glu Tyr Glu Gly His His Ser Ala Glu 
            500                 505                 510         


Gln Ile Leu Glu Phe Ile Glu Asp Leu Met Asn Pro Ser Val Val Ser 
        515                 520                 525             


Leu Thr Pro Thr Thr Phe Asn Glu Leu Val Thr Gln Arg Lys His Asn 
    530                 535                 540                 


Glu Val Trp Met Val Asp Phe Tyr Ser Pro Trp Cys His Pro Cys Gln 
545                 550                 555                 560 


Val Leu Met Pro Glu Trp Lys Arg Met Ala Arg Thr Leu Thr Gly Leu 
                565                 570                 575     


Ile Asn Val Gly Ser Ile Asp Cys Gln Gln Tyr His Ser Phe Cys Ala 
            580                 585                 590         


Gln Glu Asn Val Gln Arg Tyr Pro Glu Ile Arg Phe Phe Pro Pro Lys 
        595                 600                 605             


Ser Asn Lys Ala Tyr Gln Tyr His Ser Tyr Asn Gly Trp Asn Arg Asp 
    610                 615                 620                 


Ala Tyr Ser Leu Arg Ile Trp Gly Leu Gly Phe Leu Pro Gln Val Ser 
625                 630                 635                 640 


Thr Asp Leu Thr Pro Gln Thr Phe Ser Glu Lys Val Leu Gln Gly Lys 
                645                 650                 655     


Asn His Trp Val Ile Asp Phe Tyr Ala Pro Trp Cys Gly Pro Cys Gln 
            660                 665                 670         


Asn Phe Ala Pro Glu Phe Glu Leu Leu Ala Arg Met Ile Lys Gly Lys 
        675                 680                 685             


Val Lys Ala Gly Lys Val Asp Cys Gln Ala Tyr Ala Gln Thr Cys Gln 
    690                 695                 700                 


Lys Ala Gly Ile Arg Ala Tyr Pro Thr Val Lys Phe Tyr Phe Tyr Glu 
705                 710                 715                 720 


Arg Ala Lys Arg Asn Phe Gln Glu Glu Gln Ile Asn Thr Arg Asp Ala 
                725                 730                 735     


Lys Ala Ile Ala Ala Leu Ile Ser Glu Lys Leu Glu Thr Leu Arg Asn 
            740                 745                 750         


Gln Gly Lys Arg Asn Lys Asp Glu Leu 
        755                 760     


<210>  2636
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  2636

Met Ala His Pro Val Gln Ser Glu Phe Pro Ser Ala Gln Glu Ser Gly 
1               5                   10                  15      


Ser Ala Ala Ser Leu Asp Leu Pro Glu Met Glu Ile Leu Leu Thr Lys 
            20                  25                  30          


Ala Glu Asn Lys Asp Asp Lys Thr Leu Asn Leu Ser Lys Thr Leu Ser 
        35                  40                  45              


Gly Pro Leu Asp Leu Glu Gln Asn Gly Gln Gly Leu Pro Phe Lys Ala 
    50                  55                  60                  


Ile Ser Glu Gly His Leu Glu Ala Pro Leu Pro Arg Ser Pro Ser Arg 
65                  70                  75                  80  


Ala Ser Ser Arg Arg Ala Ser Ser Ile Ala Thr Thr Ser Tyr Ala Gln 
                85                  90                  95      


Asp Gln Glu Ala Pro Arg Asp Tyr Leu 
            100                 105 


<210>  2637
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  2637

Ser Ser Ser Ser Pro Arg Thr Pro Pro Ala Pro Ala Arg Pro Pro Cys 
1               5                   10                  15      


Ala Arg Gly Gly Pro Ser Ala Pro Arg His Val Cys Val Trp Glu Arg 
            20                  25                  30          


Ala Pro Pro Pro Ser Arg Ser Pro Arg Val Pro Arg Ser Arg Arg Gln 
        35                  40                  45              


Val Leu Pro Gly Thr Ala Pro Pro Ala Thr Pro Ser Gly Phe Glu Glu 
    50                  55                  60                  


Gly Pro Pro Ser Ser Gln Tyr Pro Trp Ala Ile Val Trp Gly Pro Thr 
65                  70                  75                  80  


Val Ser Arg Glu Asp Gly Gly Asp Pro Asn Ser Ala Asn Pro Gly Phe 
                85                  90                  95      


Leu Asp Tyr Gly Phe Ala Ala Pro His Gly Leu Ala Thr Pro His Pro 
            100                 105                 110         


Asn Ser Asp Ser Met Arg Gly Asp Gly Asp Gly Leu Ile Leu Gly Glu 
        115                 120                 125             


Ala Pro Ala Thr Leu Arg Pro Phe Leu Phe Gly Gly Arg Gly Glu Gly 
    130                 135                 140                 


Val Asp Pro 
145         


<210>  2638
<211>  599
<212>  PRT
<213>  Homo Sapiens

<400>  2638

Arg Phe Val Ala Glu Arg Asp Ser Glu Asp Asp Gly Glu Glu Pro Val 
1               5                   10                  15      


Val Phe Pro Glu Ser Pro Leu Gln Ser Pro Thr Val Leu Val Ala Val 
            20                  25                  30          


Leu Ala Arg Asn Ala Ala His Thr Leu Pro His Phe Leu Gly Cys Leu 
        35                  40                  45              


Glu Arg Leu Asp Tyr Pro Lys Ser Arg Met Ala Ile Trp Ala Ala Thr 
    50                  55                  60                  


Asp His Asn Val Asp Asn Thr Thr Glu Ile Phe Arg Glu Trp Leu Lys 
65                  70                  75                  80  


Asn Val Gln Arg Leu Tyr His Tyr Val Glu Trp Arg Pro Met Asp Glu 
                85                  90                  95      


Pro Glu Ser Tyr Pro Asp Glu Ile Gly Pro Lys His Trp Pro Thr Ser 
            100                 105                 110         


Arg Phe Ala His Val Met Lys Leu Arg Gln Ala Ala Leu Arg Thr Ala 
        115                 120                 125             


Arg Glu Lys Trp Ser Asp Tyr Ile Leu Phe Ile Asp Val Asp Asn Phe 
    130                 135                 140                 


Leu Thr Asn Pro Gln Thr Leu Asn Leu Leu Ile Ala Glu Asn Lys Thr 
145                 150                 155                 160 


Ile Val Ala Pro Met Leu Glu Ser Arg Gly Leu Tyr Ser Asn Phe Trp 
                165                 170                 175     


Cys Gly Ile Thr Pro Lys Gly Phe Tyr Lys Arg Thr Pro Asp Tyr Val 
            180                 185                 190         


Gln Ile Arg Glu Trp Lys Arg Thr Gly Cys Phe Pro Val Pro Met Val 
        195                 200                 205             


His Ser Thr Phe Leu Ile Asp Leu Arg Lys Glu Ala Ser Asp Lys Leu 
    210                 215                 220                 


Thr Phe Tyr Pro Pro His Gln Asp Tyr Thr Trp Thr Phe Asp Asp Ile 
225                 230                 235                 240 


Ile Val Phe Ala Phe Ser Ser Arg Gln Ala Gly Ile Gln Met Tyr Leu 
                245                 250                 255     


Cys Asn Arg Glu His Tyr Gly Tyr Leu Pro Ile Pro Leu Lys Pro His 
            260                 265                 270         


Gln Thr Leu Gln Glu Asp Ile Glu Asn Leu Ile His Val Gln Ile Glu 
        275                 280                 285             


Ala Met Ile Asp Arg Pro Pro Met Glu Pro Ser Gln Tyr Val Ser Val 
    290                 295                 300                 


Val Pro Lys Tyr Pro Asp Lys Met Gly Phe Asp Glu Ile Phe Met Ile 
305                 310                 315                 320 


Asn Leu Lys Arg Arg Lys Asp Arg Arg Asp Arg Met Leu Arg Thr Leu 
                325                 330                 335     


Tyr Glu Gln Glu Ile Glu Val Lys Ile Val Glu Ala Val Asp Gly Lys 
            340                 345                 350         


Ala Leu Asn Thr Ser Gln Leu Lys Ala Leu Asn Ile Glu Met Leu Pro 
        355                 360                 365             


Gly Tyr Arg Asp Pro Tyr Ser Ser Arg Pro Leu Thr Arg Gly Glu Ile 
    370                 375                 380                 


Gly Cys Phe Leu Ser His Tyr Ser Val Trp Lys Glu Val Ile Asp Arg 
385                 390                 395                 400 


Glu Leu Glu Lys Thr Leu Val Ile Glu Asp Asp Val Arg Phe Glu His 
                405                 410                 415     


Gln Phe Lys Lys Lys Leu Met Lys Leu Met Asp Asn Ile Asp Gln Ala 
            420                 425                 430         


Gln Leu Asp Trp Glu Leu Ile Tyr Ile Gly Arg Lys Arg Met Gln Val 
        435                 440                 445             


Lys Glu Pro Glu Lys Ala Val Pro Asn Val Ala Asn Leu Val Glu Ala 
    450                 455                 460                 


Asp Tyr Ser Tyr Trp Thr Leu Gly Tyr Val Ile Ser Leu Glu Gly Ala 
465                 470                 475                 480 


Gln Lys Leu Val Gly Ala Asn Pro Phe Gly Lys Met Leu Pro Val Asp 
                485                 490                 495     


Glu Phe Leu Pro Val Met Tyr Asn Lys His Pro Val Ala Glu Tyr Lys 
            500                 505                 510         


Glu Tyr Tyr Glu Ser Arg Asp Leu Lys Ala Phe Ser Ala Glu Pro Leu 
        515                 520                 525             


Leu Ile Tyr Pro Thr His Tyr Thr Gly Gln Pro Gly Tyr Leu Ser Asp 
    530                 535                 540                 


Thr Glu Thr Ser Thr Ile Trp Asp Asn Glu Thr Val Ala Thr Asp Trp 
545                 550                 555                 560 


Asp Arg Thr His Ala Trp Lys Ser Arg Lys Gln Ser Arg Ile Tyr Ser 
                565                 570                 575     


Asn Ala Lys Asn Thr Glu Ala Leu Pro Pro Pro Thr Ser Leu Asp Thr 
            580                 585                 590         


Val Pro Ser Arg Asp Glu Leu 
        595                 


<210>  2639
<211>  549
<212>  PRT
<213>  Homo Sapiens

<400>  2639

Arg Arg Ala Ala Gly Gly Leu His Leu Leu Pro Trp Ser Arg Gly Glu 
1               5                   10                  15      


Pro Gly Ala Ala Glu Pro Ser Ala Cys Leu Glu Ala Ala Thr Arg Ala 
            20                  25                  30          


Trp Arg Gly Leu Arg Glu Arg Gly Glu Val Val Pro Leu Gly Pro Gly 
        35                  40                  45              


Val Pro Ala Leu Val Ala Asn Gly Phe Leu Ala Leu Asp Val Ala Ala 
    50                  55                  60                  


Asn Arg Leu Trp Val Thr Pro Gly Glu Arg Glu Pro Ala Val Ala Pro 
65                  70                  75                  80  


Asp Phe Val Pro Phe Val Gln Leu Arg Pro Leu Ser Ala Leu Ala Glu 
                85                  90                  95      


Ala Gly Glu Ala Val Leu Leu Leu Arg Glu Gly Leu Leu Arg Arg Val 
            100                 105                 110         


Arg Cys Leu Gln Leu Gly Ser Pro Gly Pro Gly Pro Val Ala Ala Gly 
        115                 120                 125             


Pro Gly Pro Ala Ser Val Ser Gly Leu Ala Ala Gly Ser Gly Arg Asp 
    130                 135                 140                 


Cys Val Leu Leu Gln Glu Asp Phe Leu Ala His Arg Gly Arg Pro His 
145                 150                 155                 160 


Val Tyr Leu Gln Arg Ile Gln Leu Asn Asn Pro Thr Glu Arg Val Ala 
                165                 170                 175     


Ala Leu Gln Thr Val Gly Pro Thr Ala Gly Pro Ala Pro Lys Ala Phe 
            180                 185                 190         


Thr Ser Thr Leu Glu Lys Val Gly Asp His Gln Phe Leu Leu Tyr Ser 
        195                 200                 205             


Gly Arg Ser Pro Pro Thr Pro Thr Gly Leu Val His Leu Val Val Val 
    210                 215                 220                 


Ala Ala Lys Lys Leu Val Asn Arg Leu Gln Val Ala Pro Lys Thr Gln 
225                 230                 235                 240 


Leu Asp Glu Thr Val Leu Trp Val Val His Val Ser Gly Pro Ile Asn 
                245                 250                 255     


Pro Gln Val Leu Lys Ser Lys Ala Ala Lys Glu Leu Lys Ala Leu Gln 
            260                 265                 270         


Asp Leu Ala Arg Lys Glu Met Leu Glu Leu Leu Asp Met Pro Ala Ala 
        275                 280                 285             


Glu Leu Leu Gln Asp His Gln Leu Leu Trp Ala Gln Leu Phe Ser Pro 
    290                 295                 300                 


Gly Val Glu Met Lys Lys Ile Thr Asp Thr His Thr Pro Ser Gly Leu 
305                 310                 315                 320 


Thr Val Asn Leu Thr Leu Tyr Tyr Met Leu Ser Cys Ser Pro Ala Pro 
                325                 330                 335     


Leu Leu Ser Pro Ser Leu Ser His Arg Glu Arg Asp Gln Met Glu Ser 
            340                 345                 350         


Thr Leu Asn Tyr Glu Asp His Cys Phe Ser Gly His Ala Thr Met His 
        355                 360                 365             


Ala Glu Asn Leu Trp Pro Gly Arg Leu Ser Ser Val Gln Gln Ile Leu 
    370                 375                 380                 


Gln Leu Ser Asp Leu Trp Arg Leu Thr Leu Gln Lys Arg Gly Cys Lys 
385                 390                 395                 400 


Gly Leu Val Lys Val Gly Ala Pro Gly Ile Leu Gln Gly Met Val Leu 
                405                 410                 415     


Ser Phe Gly Gly Leu Gln Phe Thr Glu Asn His Leu Gln Phe Gln Ala 
            420                 425                 430         


Asp Pro Asp Val Leu His Asn Ser Tyr Ala Leu His Gly Ile Arg Tyr 
        435                 440                 445             


Lys Asn Asp His Ile Asn Leu Ala Val Leu Ala Asp Ala Glu Gly Lys 
    450                 455                 460                 


Pro Tyr Leu His Val Ser Val Glu Ser Arg Gly Gln Pro Val Lys Ile 
465                 470                 475                 480 


Tyr Ala Cys Lys Ala Gly Cys Leu Asp Glu Pro Val Glu Leu Thr Ser 
                485                 490                 495     


Ala Pro Thr Gly His Thr Phe Ser Val Met Val Thr Gln Pro Ile Thr 
            500                 505                 510         


Pro Leu Leu Tyr Ile Ser Thr Asp Leu Thr His Leu Gln Asp Leu Arg 
        515                 520                 525             


His Thr Leu His Leu Lys Ala Ile Leu Ala His Asp Glu His Met Ala 
    530                 535                 540                 


Gln Gln Asp Pro Gly 
545                 


<210>  2640
<211>  1040
<212>  PRT
<213>  Homo Sapiens

<400>  2640

Asp Val Val Arg Ser Glu Gln Gln Ile Pro Leu Ser Val Val Lys Leu 
1               5                   10                  15      


Trp Ala Ser Ala Phe Gly Gly Glu Ile Lys Ser Ile Ala Ala Lys Tyr 
            20                  25                  30          


Ser Gly Ser Gln Leu Leu Gln Lys Lys Tyr Lys Glu Tyr Glu Lys Asp 
        35                  40                  45              


Val Ala Ile Glu Glu Ile Asp Gly Leu Gln Leu Val Lys Lys Leu Ala 
    50                  55                  60                  


Lys Asn Met Glu Glu Met Phe His Lys Lys Ser Glu Ala Val Arg Arg 
65                  70                  75                  80  


Leu Val Glu Ala Ala Glu Glu Ala His Leu Lys His Glu Phe Asp Ala 
                85                  90                  95      


Asp Leu Gln Tyr Glu Tyr Phe Asn Ala Val Leu Ile Asn Glu Arg Asp 
            100                 105                 110         


Lys Asp Gly Asn Phe Leu Glu Leu Gly Lys Glu Phe Ile Leu Ala Pro 
        115                 120                 125             


Asn Asp His Phe Asn Asn Leu Pro Val Asn Ile Ser Leu Ser Asp Val 
    130                 135                 140                 


Gln Val Pro Thr Asn Met Tyr Asn Lys Asp Pro Ala Ile Val Asn Gly 
145                 150                 155                 160 


Val Tyr Trp Ser Glu Ser Leu Asn Lys Val Phe Val Asp Asn Phe Asp 
                165                 170                 175     


Arg Asp Pro Ser Leu Ile Trp Gln Tyr Phe Gly Ser Ala Lys Gly Phe 
            180                 185                 190         


Phe Arg Gln Tyr Pro Gly Ile Lys Trp Glu Pro Asp Glu Asn Gly Val 
        195                 200                 205             


Ile Ala Phe Asp Cys Arg Asn Arg Lys Trp Tyr Ile Gln Ala Ala Thr 
    210                 215                 220                 


Ser Pro Lys Asp Val Val Ile Leu Val Asp Val Ser Gly Ser Met Lys 
225                 230                 235                 240 


Gly Leu Arg Leu Thr Ile Ala Lys Gln Thr Val Ser Ser Ile Leu Asp 
                245                 250                 255     


Thr Leu Gly Asp Asp Asp Phe Phe Asn Ile Ile Ala Tyr Asn Glu Glu 
            260                 265                 270         


Leu His Tyr Val Glu Pro Cys Leu Asn Gly Thr Leu Val Gln Ala Asp 
        275                 280                 285             


Arg Thr Asn Lys Glu His Phe Arg Glu His Leu Asp Lys Leu Phe Ala 
    290                 295                 300                 


Lys Gly Ile Gly Met Leu Asp Ile Ala Leu Asn Glu Ala Phe Asn Ile 
305                 310                 315                 320 


Leu Ser Asp Phe Asn His Thr Gly Gln Gly Ser Ile Cys Ser Gln Ala 
                325                 330                 335     


Ile Met Leu Ile Thr Asp Gly Ala Val Asp Thr Tyr Asp Thr Ile Phe 
            340                 345                 350         


Ala Lys Tyr Asn Trp Pro Asp Arg Lys Val Arg Ile Phe Thr Tyr Leu 
        355                 360                 365             


Ile Gly Arg Glu Ala Ala Phe Ala Asp Asn Leu Lys Trp Met Ala Cys 
    370                 375                 380                 


Ala Asn Lys Gly Phe Phe Thr Gln Ile Ser Thr Leu Ala Asp Val Gln 
385                 390                 395                 400 


Glu Asn Val Met Glu Tyr Leu His Val Leu Ser Arg Pro Lys Val Ile 
                405                 410                 415     


Asp Gln Glu His Asp Val Val Trp Thr Glu Ala Tyr Ile Asp Ser Thr 
            420                 425                 430         


Leu Pro Gln Ala Gln Lys Leu Thr Asp Asp Gln Gly Pro Val Leu Met 
        435                 440                 445             


Thr Thr Val Ala Met Pro Val Phe Ser Lys Gln Asn Glu Thr Arg Ser 
    450                 455                 460                 


Lys Gly Ile Leu Leu Gly Val Val Gly Thr Asp Val Pro Val Lys Glu 
465                 470                 475                 480 


Leu Leu Lys Thr Ile Pro Lys Tyr Lys Leu Gly Ile His Gly Tyr Ala 
                485                 490                 495     


Phe Ala Ile Thr Asn Asn Gly Tyr Ile Leu Thr His Pro Glu Leu Arg 
            500                 505                 510         


Leu Leu Tyr Glu Glu Gly Lys Lys Arg Arg Lys Pro Asn Tyr Ser Ser 
        515                 520                 525             


Val Asp Leu Ser Glu Val Glu Trp Glu Asp Arg Asp Asp Val Leu Arg 
    530                 535                 540                 


Asn Ala Met Val Asn Arg Lys Thr Gly Lys Phe Ser Met Glu Val Lys 
545                 550                 555                 560 


Lys Thr Val Asp Lys Gly Lys Arg Val Leu Val Met Thr Asn Asp Tyr 
                565                 570                 575     


Tyr Tyr Thr Asp Ile Lys Gly Thr Pro Phe Ser Leu Gly Val Ala Leu 
            580                 585                 590         


Ser Arg Gly His Gly Lys Tyr Phe Phe Arg Gly Asn Val Thr Ile Glu 
        595                 600                 605             


Glu Gly Leu His Asp Leu Glu His Pro Asp Val Ser Leu Ala Asp Glu 
    610                 615                 620                 


Trp Ser Tyr Cys Asn Thr Asp Leu His Pro Glu His Arg His Leu Ser 
625                 630                 635                 640 


Gln Leu Glu Ala Ile Lys Leu Tyr Leu Lys Gly Lys Glu Pro Leu Leu 
                645                 650                 655     


Gln Cys Asp Lys Glu Leu Ile Gln Glu Val Leu Phe Asp Ala Val Val 
            660                 665                 670         


Ser Ala Pro Ile Glu Ala Tyr Trp Thr Ser Leu Ala Leu Asn Lys Ser 
        675                 680                 685             


Glu Asn Ser Asp Lys Gly Val Glu Val Ala Phe Leu Gly Thr Arg Thr 
    690                 695                 700                 


Gly Leu Ser Arg Ile Asn Leu Phe Val Gly Ala Glu Gln Leu Thr Asn 
705                 710                 715                 720 


Gln Asp Phe Leu Lys Ala Gly Asp Lys Glu Asn Ile Phe Asn Ala Asp 
                725                 730                 735     


His Phe Pro Leu Trp Tyr Arg Arg Ala Ala Glu Gln Ile Pro Gly Ser 
            740                 745                 750         


Phe Val Tyr Ser Ile Pro Phe Ser Thr Gly Pro Val Asn Lys Ser Asn 
        755                 760                 765             


Val Val Thr Ala Ser Thr Ser Ile Gln Leu Leu Asp Glu Arg Lys Ser 
    770                 775                 780                 


Pro Val Val Ala Ala Val Gly Ile Gln Met Lys Leu Glu Phe Phe Gln 
785                 790                 795                 800 


Arg Lys Phe Trp Thr Ala Ser Arg Gln Cys Ala Ser Leu Asp Gly Lys 
                805                 810                 815     


Cys Ser Ile Ser Cys Asp Asp Glu Thr Val Asn Cys Tyr Leu Ile Asp 
            820                 825                 830         


Asn Asn Gly Phe Ile Leu Val Ser Glu Asp Tyr Thr Gln Thr Gly Asp 
        835                 840                 845             


Phe Phe Gly Glu Ile Glu Gly Ala Val Met Asn Lys Leu Leu Thr Met 
    850                 855                 860                 


Gly Ser Phe Lys Arg Ile Thr Leu Tyr Asp Tyr Gln Ala Met Cys Arg 
865                 870                 875                 880 


Ala Asn Lys Glu Ser Ser Asp Gly Ala His Gly Leu Leu Asp Pro Tyr 
                885                 890                 895     


Asn Ala Phe Leu Ser Ala Val Lys Trp Ile Met Thr Glu Leu Val Leu 
            900                 905                 910         


Phe Leu Val Glu Phe Asn Leu Cys Ser Trp Trp His Ser Asp Met Thr 
        915                 920                 925             


Ala Lys Ala Gln Lys Leu Lys Gln Thr Leu Glu Pro Cys Asp Thr Glu 
    930                 935                 940                 


Tyr Pro Ala Phe Val Ser Glu Arg Thr Ile Lys Glu Thr Thr Gly Asn 
945                 950                 955                 960 


Ile Ala Cys Glu Asp Cys Ser Lys Ser Phe Val Ile Gln Gln Ile Pro 
                965                 970                 975     


Ser Ser Asn Leu Phe Met Val Val Val Asp Ser Ser Cys Leu Cys Glu 
            980                 985                 990         


Ser Val Ala Pro Ile Thr Met Ala  Pro Ile Glu Ile Arg  Tyr Asn Glu 
        995                 1000                 1005             


Ser Leu  Lys Cys Glu Arg Leu  Lys Ala Gln Lys Ile  Arg Arg Arg 
    1010                 1015                 1020             


Pro Glu  Ser Cys His Gly Phe  His Pro Glu Glu Asn  Ala Arg Glu 
    1025                 1030                 1035             


Cys Gly  
    1040 


<210>  2641
<211>  466
<212>  PRT
<213>  Homo Sapiens

<400>  2641

Leu Leu His Pro Asp Ser Arg Ser His Pro Arg Ser Leu Glu Lys Ser 
1               5                   10                  15      


Ala Trp Arg Ala Phe Lys Glu Ser Gln Cys His His Met Leu Lys His 
            20                  25                  30          


Leu His Asn Gly Ala Arg Ile Thr Val Gln Met Pro Pro Thr Ile Glu 
        35                  40                  45              


Gly His Trp Val Ser Thr Gly Cys Glu Val Arg Ser Gly Pro Glu Phe 
    50                  55                  60                  


Ile Thr Arg Ser Tyr Arg Phe Tyr His Asn Asn Thr Phe Lys Ala Tyr 
65                  70                  75                  80  


Gln Phe Tyr Tyr Gly Ser Asn Arg Cys Thr Asn Pro Thr Tyr Thr Leu 
                85                  90                  95      


Ile Ile Arg Gly Lys Ile Arg Leu Arg Gln Ala Ser Trp Ile Ile Arg 
            100                 105                 110         


Gly Gly Thr Glu Ala Asp Tyr Gln Leu His Asn Val Gln Val Ile Cys 
        115                 120                 125             


His Thr Glu Ala Val Ala Glu Lys Leu Gly Gln Gln Val Asn Arg Thr 
    130                 135                 140                 


Cys Pro Gly Phe Leu Ala Asp Gly Gly Pro Trp Val Gln Asp Val Ala 
145                 150                 155                 160 


Tyr Asp Leu Trp Arg Glu Glu Asn Gly Cys Glu Cys Thr Lys Ala Val 
                165                 170                 175     


Asn Phe Ala Met His Glu Leu Gln Leu Ile Arg Val Glu Lys Gln Tyr 
            180                 185                 190         


Leu His His Asn Leu Asp His Leu Val Glu Glu Leu Phe Leu Gly Asp 
        195                 200                 205             


Ile His Thr Asp Ala Thr Gln Arg Met Phe Tyr Arg Pro Ser Ser Tyr 
    210                 215                 220                 


Gln Pro Pro Leu Gln Asn Ala Lys Asn His Asp His Ala Cys Ile Ala 
225                 230                 235                 240 


Cys Arg Ile Ile Tyr Arg Ser Asp Glu His His Pro Pro Ile Leu Pro 
                245                 250                 255     


Pro Lys Ala Asp Leu Thr Ile Gly Leu His Gly Glu Trp Val Ser Gln 
            260                 265                 270         


Arg Cys Glu Val Arg Pro Glu Val Leu Phe Leu Thr Arg His Phe Ile 
        275                 280                 285             


Phe His Asp Asn Asn Asn Thr Trp Glu Gly His Tyr Tyr His Tyr Ser 
    290                 295                 300                 


Asp Pro Val Cys Lys His Pro Thr Phe Ser Ile Tyr Ala Arg Gly Arg 
305                 310                 315                 320 


Tyr Ser Arg Gly Val Leu Ser Ser Arg Val Met Gly Gly Thr Glu Phe 
                325                 330                 335     


Val Phe Lys Val Asn His Met Lys Val Thr Pro Met Asp Ala Ala Thr 
            340                 345                 350         


Ala Ser Leu Leu Asn Val Phe Asn Gly Asn Glu Cys Gly Ala Glu Gly 
        355                 360                 365             


Ser Trp Gln Val Gly Ile Gln Gln Asp Val Thr His Thr Asn Gly Cys 
    370                 375                 380                 


Val Ala Leu Gly Ile Lys Leu Pro His Thr Glu Tyr Glu Ile Phe Lys 
385                 390                 395                 400 


Met Glu Gln Asp Ala Arg Gly Arg Tyr Leu Leu Phe Asn Gly Gln Arg 
                405                 410                 415     


Pro Ser Asp Gly Ser Ser Pro Asp Arg Pro Glu Lys Arg Ala Thr Ser 
            420                 425                 430         


Tyr Gln Met Pro Leu Val Gln Cys Ala Ser Ser Ser Pro Arg Ala Glu 
        435                 440                 445             


Asp Leu Ala Glu Asp Ser Gly Ser Ser Leu Tyr Gly Arg Ala Pro Gly 
    450                 455                 460                 


Arg His 
465     


<210>  2642
<211>  635
<212>  PRT
<213>  Homo Sapiens

<400>  2642

Gln Ala Gln Tyr Pro Val Val Asn Thr Asn Tyr Gly Lys Ile Arg Gly 
1               5                   10                  15      


Leu Arg Thr Pro Leu Pro Asn Glu Ile Leu Gly Pro Val Glu Gln Tyr 
            20                  25                  30          


Leu Gly Val Pro Tyr Ala Ser Pro Pro Thr Gly Glu Arg Arg Phe Gln 
        35                  40                  45              


Pro Pro Glu Pro Pro Ser Ser Trp Thr Gly Ile Arg Asn Thr Thr Gln 
    50                  55                  60                  


Phe Ala Ala Val Cys Pro Gln His Leu Asp Glu Arg Ser Leu Leu His 
65                  70                  75                  80  


Asp Met Leu Pro Ile Trp Phe Thr Ala Asn Leu Asp Thr Leu Met Thr 
                85                  90                  95      


Tyr Val Gln Asp Gln Asn Glu Asp Cys Leu Tyr Leu Asn Ile Tyr Val 
            100                 105                 110         


Pro Thr Glu Asp Asp Ile His Asp Gln Asn Ser Lys Lys Pro Val Met 
        115                 120                 125             


Val Tyr Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly Asn Met Ile 
    130                 135                 140                 


Asp Gly Ser Ile Leu Ala Ser Tyr Gly Asn Val Ile Val Ile Thr Ile 
145                 150                 155                 160 


Asn Tyr Arg Leu Gly Ile Leu Gly Phe Leu Ser Thr Gly Asp Gln Ala 
                165                 170                 175     


Ala Lys Gly Asn Tyr Gly Leu Leu Asp Gln Ile Gln Ala Leu Arg Trp 
            180                 185                 190         


Ile Glu Glu Asn Val Gly Ala Phe Gly Gly Asp Pro Lys Arg Val Thr 
        195                 200                 205             


Ile Phe Gly Ser Gly Ala Gly Ala Ser Cys Val Ser Leu Leu Thr Leu 
    210                 215                 220                 


Ser His Tyr Ser Glu Gly Leu Phe Gln Lys Ala Ile Ile Gln Ser Gly 
225                 230                 235                 240 


Thr Ala Leu Ser Ser Trp Ala Val Asn Tyr Gln Pro Ala Lys Tyr Thr 
                245                 250                 255     


Arg Ile Leu Ala Asp Lys Val Gly Cys Asn Met Leu Asp Thr Thr Asp 
            260                 265                 270         


Met Val Glu Cys Leu Arg Asn Lys Asn Tyr Lys Glu Leu Ile Gln Gln 
        275                 280                 285             


Thr Ile Thr Pro Ala Thr Tyr His Ile Ala Phe Gly Pro Val Ile Asp 
    290                 295                 300                 


Gly Asp Val Ile Pro Asp Asp Pro Gln Ile Leu Met Glu Gln Gly Glu 
305                 310                 315                 320 


Phe Leu Asn Tyr Asp Ile Met Leu Gly Val Asn Gln Gly Glu Gly Leu 
                325                 330                 335     


Lys Phe Val Asp Gly Ile Val Asp Asn Glu Asp Gly Val Thr Pro Asn 
            340                 345                 350         


Asp Phe Asp Phe Ser Val Ser Asn Phe Val Asp Asn Leu Tyr Gly Tyr 
        355                 360                 365             


Pro Glu Gly Lys Asp Thr Leu Arg Glu Thr Ile Lys Phe Met Tyr Thr 
    370                 375                 380                 


Asp Trp Ala Asp Lys Glu Asn Pro Glu Thr Arg Arg Lys Thr Leu Val 
385                 390                 395                 400 


Ala Leu Phe Thr Asp His Gln Trp Val Ala Pro Ala Val Ala Thr Ala 
                405                 410                 415     


Asp Leu His Ala Gln Tyr Gly Ser Pro Thr Tyr Phe Tyr Ala Phe Tyr 
            420                 425                 430         


His His Cys Gln Ser Glu Met Lys Pro Ser Trp Ala Asp Ser Ala His 
        435                 440                 445             


Gly Asp Glu Val Pro Tyr Val Phe Gly Ile Pro Met Ile Gly Pro Thr 
    450                 455                 460                 


Glu Leu Phe Ser Cys Asn Phe Ser Lys Asn Asp Val Met Leu Ser Ala 
465                 470                 475                 480 


Val Val Met Thr Tyr Trp Thr Asn Phe Ala Lys Thr Gly Asp Pro Asn 
                485                 490                 495     


Gln Pro Val Pro Gln Asp Thr Lys Phe Ile His Thr Lys Pro Asn Arg 
            500                 505                 510         


Phe Glu Glu Val Ala Trp Ser Lys Tyr Asn Pro Lys Asp Gln Leu Tyr 
        515                 520                 525             


Leu His Ile Gly Leu Lys Pro Arg Val Arg Asp His Tyr Arg Ala Thr 
    530                 535                 540                 


Lys Val Ala Phe Trp Leu Glu Leu Val Pro His Leu His Asn Leu Asn 
545                 550                 555                 560 


Glu Ile Phe Gln Tyr Val Ser Thr Thr Thr Lys Val Pro Pro Pro Asp 
                565                 570                 575     


Met Thr Ser Phe Pro Tyr Gly Thr Arg Arg Ser Pro Ala Lys Ile Trp 
            580                 585                 590         


Pro Thr Thr Lys Arg Pro Ala Ile Thr Pro Ala Asn Asn Pro Lys His 
        595                 600                 605             


Ser Lys Asp Pro His Lys Thr Gly Pro Glu Asp Thr Thr Val Leu Ile 
    610                 615                 620                 


Glu Thr Lys Arg Asp Tyr Ser Thr Glu Leu Ser 
625                 630                 635 


<210>  2643
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2643

Leu Cys Ser Gly Ser Ser Tyr Phe Val Leu Ala Asn Gly His Ile Leu 
1               5                   10                  15      


Pro Asn Ser Glu Asn Ala His Gly Gln Ser Leu Glu Glu Asp Ser Ala 
            20                  25                  30          


Leu Glu Ala Leu Leu Asn Phe Phe Phe Pro Thr Thr Cys Asn Leu Arg 
        35                  40                  45              


Glu Asn Gln Val Ala Lys Pro Cys Asn Glu Leu Gln Asp Leu Ser Glu 
    50                  55                  60                  


Ser Glu Cys Leu Arg His Lys Cys Cys Phe Ser Ser Ser Gly Thr Thr 
65                  70                  75                  80  


Ser Phe Lys Cys Phe Ala Pro Phe Arg Asp Val Pro Lys Gln 
                85                  90                  


<210>  2644
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  2644

Gly Met Leu Lys Glu Glu Asp Asp Asp Thr Glu Arg Leu Pro Ser Lys 
1               5                   10                  15      


Cys Glu Val Cys Lys Leu Leu Ser Thr Glu Leu Gln Ala Glu Leu Ser 
            20                  25                  30          


Arg Thr Gly Arg Ser Arg Glu Val Leu Glu Leu Gly Gln Val Leu Asp 
        35                  40                  45              


Thr Gly Lys Arg Lys Arg His Val Pro Tyr Ser Val Ser Glu Thr Arg 
    50                  55                  60                  


Leu Glu Glu Ala Leu Glu Asn Leu Cys Glu Arg Ile Leu Asp Tyr Ser 
65                  70                  75                  80  


Val His Ala Glu Arg Lys Gly Ser Leu Arg Tyr Ala Lys Gly Gln Ser 
                85                  90                  95      


Gln Thr Met Ala Thr Leu Lys Gly Leu Val Gln Lys Gly Val Lys Val 
            100                 105                 110         


Asp Leu Gly Ile Pro Leu Glu Leu Trp Asp Glu Pro Ser Val Glu Val 
        115                 120                 125             


Thr Tyr Leu Lys Lys Gln Cys Glu Thr Met Leu Glu Glu Phe Glu Asp 
    130                 135                 140                 


Ile Val Gly Asp Trp Tyr Phe His His Gln Glu Gln Pro Leu Gln Asn 
145                 150                 155                 160 


Phe Leu Cys Glu Gly His Val Leu Pro Ala Ala Glu Thr Ala Cys Leu 
                165                 170                 175     


Gln Glu Thr Trp Thr Gly Lys Glu Ile Thr Asp Gly Glu Glu Lys Thr 
            180                 185                 190         


Glu Gly Glu Glu Glu Gln Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu 
        195                 200                 205             


Gly Gly Asp Lys Met Thr Lys Thr Gly Ser His Pro Lys Leu Asp Arg 
    210                 215                 220                 


Glu Asp Leu 
225         


<210>  2645
<211>  140
<212>  PRT
<213>  Homo Sapiens

<400>  2645

His Glu Ser Ala Ala Met Ala Ala Ser Ala Asn Ile Glu Asn Ser Gly 
1               5                   10                  15      


Leu Pro His Asn Ser Ser Ala Asn Ser Thr Glu Thr Leu Gln His Val 
            20                  25                  30          


Pro Ser Asp His Thr Asn Glu Thr Ser Asn Ser Thr Val Lys Pro Pro 
        35                  40                  45              


Thr Ser Val Ala Ser Asp Ser Ser Asn Thr Thr Val Thr Thr Met Lys 
    50                  55                  60                  


Pro Thr Ala Ala Ser Asn Thr Thr Thr Pro Gly Met Val Ser Thr Asn 
65                  70                  75                  80  


Met Thr Ser Thr Thr Leu Lys Ser Thr Pro Lys Thr Thr Ser Val Ser 
                85                  90                  95      


Gln Asn Thr Ser Gln Ile Ser Thr Ser Thr Met Thr Val Thr His Asn 
            100                 105                 110         


Ser Ser Val Thr Ser Ala Ala Ser Ser Val Thr Ile Thr Thr Thr Met 
        115                 120                 125             


His Ser Glu Ala Lys Lys Gly Ser Lys Phe Asp Thr 
    130                 135                 140 


<210>  2646
<211>  531
<212>  PRT
<213>  Homo Sapiens

<400>  2646

Ser Glu Ala Lys Val Thr Arg Ser Cys Ala Glu Thr Arg Gln Val Leu 
1               5                   10                  15      


Gly Ala Arg Gly Tyr Ser Leu Asn Leu Ile Pro Pro Ala Leu Ile Ser 
            20                  25                  30          


Gly Glu His Leu Arg Val Cys Pro Gln Glu Tyr Thr Cys Cys Ser Ser 
        35                  40                  45              


Glu Thr Glu Gln Arg Leu Ile Arg Glu Thr Glu Ala Thr Phe Arg Gly 
    50                  55                  60                  


Leu Val Glu Asp Ser Gly Ser Phe Leu Val His Thr Leu Ala Ala Arg 
65                  70                  75                  80  


His Arg Lys Phe Asp Glu Phe Phe Leu Glu Met Leu Ser Val Ala Gln 
                85                  90                  95      


His Ser Leu Thr Gln Leu Phe Ser His Ser Tyr Gly Arg Leu Tyr Ala 
            100                 105                 110         


Gln His Ala Leu Ile Phe Asn Gly Leu Phe Ser Arg Leu Arg Asp Phe 
        115                 120                 125             


Tyr Gly Glu Ser Gly Glu Gly Leu Asp Asp Thr Leu Ala Asp Phe Trp 
    130                 135                 140                 


Ala Gln Leu Leu Glu Arg Val Phe Pro Leu Leu His Pro Gln Tyr Ser 
145                 150                 155                 160 


Phe Pro Pro Asp Tyr Leu Leu Cys Leu Ser Arg Leu Ala Ser Ser Thr 
                165                 170                 175     


Asp Gly Ser Leu Gln Pro Phe Gly Asp Ser Pro Arg Arg Leu Arg Leu 
            180                 185                 190         


Gln Ile Thr Arg Thr Leu Val Ala Ala Arg Ala Phe Val Gln Gly Leu 
        195                 200                 205             


Glu Thr Gly Arg Asn Val Val Ser Glu Ala Leu Lys Val Pro Val Ser 
    210                 215                 220                 


Glu Gly Cys Ser Gln Ala Leu Met Arg Leu Ile Gly Cys Pro Leu Cys 
225                 230                 235                 240 


Arg Gly Val Pro Ser Leu Met Pro Cys Gln Gly Phe Cys Leu Asn Val 
                245                 250                 255     


Val Arg Gly Cys Leu Ser Ser Arg Gly Leu Glu Pro Asp Trp Gly Asn 
            260                 265                 270         


Tyr Leu Asp Gly Leu Leu Ile Leu Ala Asp Lys Leu Gln Gly Pro Phe 
        275                 280                 285             


Ser Phe Glu Leu Thr Ala Glu Ser Ile Gly Val Lys Ile Ser Glu Gly 
    290                 295                 300                 


Leu Met Tyr Leu Gln Glu Asn Ser Ala Lys Val Ser Ala Gln Val Phe 
305                 310                 315                 320 


Gln Glu Cys Gly Pro Pro Asp Pro Val Pro Ala Arg Asn Arg Arg Ala 
                325                 330                 335     


Pro Pro Pro Arg Glu Glu Ala Gly Arg Leu Trp Ser Met Val Thr Glu 
            340                 345                 350         


Glu Glu Arg Pro Thr Thr Ala Ala Gly Thr Asn Leu His Arg Leu Val 
        355                 360                 365             


Trp Glu Leu Arg Glu Arg Leu Ala Arg Met Arg Gly Phe Trp Ala Arg 
    370                 375                 380                 


Leu Ser Leu Thr Val Cys Gly Asp Ser Arg Met Ala Ala Asp Ala Ser 
385                 390                 395                 400 


Leu Glu Ala Ala Pro Cys Trp Thr Gly Ala Gly Arg Gly Arg Tyr Leu 
                405                 410                 415     


Pro Pro Val Val Gly Gly Ser Pro Ala Glu Gln Val Asn Asn Pro Glu 
            420                 425                 430         


Leu Lys Val Asp Ala Ser Gly Pro Asp Val Pro Thr Arg Arg Arg Arg 
        435                 440                 445             


Leu Gln Leu Arg Ala Ala Thr Ala Arg Met Lys Thr Ala Ala Leu Gly 
    450                 455                 460                 


His Asp Leu Asp Gly Gln Asp Ala Asp Glu Asp Ala Ser Gly Ser Gly 
465                 470                 475                 480 


Gly Gly Gln Gln Tyr Ala Asp Asp Trp Met Ala Gly Ala Val Ala Pro 
                485                 490                 495     


Pro Ala Arg Pro Pro Arg Pro Pro Tyr Pro Pro Arg Arg Asp Gly Ser 
            500                 505                 510         


Gly Gly Lys Gly Gly Gly Gly Ser Ala Arg Tyr Asn Gln Gly Arg Ser 
        515                 520                 525             


Arg Ser Gly 
    530     


<210>  2647
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  2647

Val Asp Lys Ala Asp Asp Glu Asp Asp Glu Asp Leu Thr Val Asn Lys 
1               5                   10                  15      


Thr Trp Val Leu Ala Pro Lys Ile His Glu Gly Asp Ile Thr Gln Ile 
            20                  25                  30          


Leu Asn Ser Leu Leu Gln Gly Tyr Asp Asn Lys Leu Arg Pro Asp Ile 
        35                  40                  45              


Gly Val Arg Pro Thr Val Ile Glu Thr Asp Val Tyr Val Asn Ser Ile 
    50                  55                  60                  


Gly Pro Val Asp Pro Ile Asn Met Glu Tyr Thr Ile Asp Ile Ile Phe 
65                  70                  75                  80  


Ala Gln Thr Trp Phe Asp Ser Arg Leu Lys Phe Asn Ser Thr Met Lys 
                85                  90                  95      


Val Leu Met Leu Asn Ser Asn Met Val Gly Lys Ile Trp Ile Pro Asp 
            100                 105                 110         


Thr Phe Phe Arg Asn Ser Arg Lys Ser Asp Ala His Trp Ile Thr Thr 
        115                 120                 125             


Pro Asn Arg Leu Leu Arg Ile Trp Asn Asp Gly Arg Val Leu Tyr Thr 
    130                 135                 140                 


Leu Arg Leu Thr Ile Asn Ala Glu Cys Tyr Leu Gln Leu His Asn Phe 
145                 150                 155                 160 


Pro Met Asp Glu His Ser Cys Pro Leu Glu Phe Ser Ser Tyr Gly Tyr 
                165                 170                 175     


Pro Lys Asn Glu Ile Glu Tyr Lys Trp Lys Lys Pro Ser Val Glu Val 
            180                 185                 190         


Ala Asp Pro Lys Tyr Trp Arg Leu Tyr Gln Phe Ala Phe Val Gly Leu 
        195                 200                 205             


Arg Asn Ser Thr Glu Ile Thr His Thr Ile Ser Gly Asp Tyr Val Ile 
    210                 215                 220                 


Met Thr Ile Phe Phe Asp Leu Ser Arg Arg Met Gly Tyr 
225                 230                 235         


<210>  2648
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  2648

Ser Asn Trp Gly Cys Tyr Gly Asn Ile Gln Ser Leu Asp Thr Pro Gly 
1               5                   10                  15      


Ala Ser Cys Gly Ile Gly Arg Arg His Gly Leu Asn Tyr Cys Gly Val 
            20                  25                  30          


Arg Ala Ser Glu Arg Leu Ala Glu Ile Asp Met Pro Tyr Leu Leu Lys 
        35                  40                  45              


Tyr Gln Pro Met Met Gln Thr Ile Gly Gln Lys Tyr Cys Met Asp Pro 
    50                  55                  60                  


Ala Val Ile Ala Gly Val Leu Ser Arg Lys Ser Pro Gly Asp Lys Ile 
65                  70                  75                  80  


Leu Val Asn Met Gly Asp Arg Thr Ser Met Val Gln Asp Pro Gly Ser 
                85                  90                  95      


Gln Ala Pro Thr Ser Trp Ile Ser Glu Ser Gln Val Ser Gln Thr Thr 
            100                 105                 110         


Glu Val Leu Thr Thr Arg Ile Lys Glu Ile Gln Arg Arg Phe Pro Thr 
        115                 120                 125             


Trp Thr Pro Asp Gln Tyr Leu Arg Gly Gly Leu Cys Ala Tyr Ser Gly 
    130                 135                 140                 


Gly Ala Gly Tyr Val Arg Ser Ser Gln Asp Leu Ser Cys Asp Phe Cys 
145                 150                 155                 160 


Asn Asp Val Leu Ala Arg Ala Lys Tyr Leu Lys Arg His Gly Phe 
                165                 170                 175 


<210>  2649
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  2649

Ile Gln Ala Lys Leu Ile Phe Leu Asn Phe Val Arg Val Pro Tyr Phe 
1               5                   10                  15      


Ile Asp Leu Lys Lys Pro Gln Asp Gln Gly Leu Asn His Thr Cys Asn 
            20                  25                  30          


Tyr Tyr Leu Gln Pro Glu Glu Asp Val Thr Ile Gly Val Trp His Thr 
        35                  40                  45              


Val Pro Ala Val Trp Trp Lys Asn Ala Gln Gly Lys Asp Gln Met Trp 
    50                  55                  60                  


Tyr Glu Asp Ala Leu Ala Ser Ser His Pro Ile Ile Leu Tyr Leu His 
65                  70                  75                  80  


Gly Asn Ala Gly Thr Arg Gly Gly Asp His Arg Val Glu Leu Tyr Lys 
                85                  90                  95      


Val Leu Ser Ser Leu Gly Tyr His Val Val Thr Phe Asp Tyr Arg Gly 
            100                 105                 110         


Trp Gly Asp Ser Val Gly Thr Pro Ser Glu Arg Gly Met Thr Tyr Asp 
        115                 120                 125             


Ala Leu His Val Phe Asp Trp Ile Lys Ala Arg Ser Gly Asp Asn Pro 
    130                 135                 140                 


Val Tyr Ile Trp Gly His Ser Leu Gly Thr Gly Val Ala Thr Asn Leu 
145                 150                 155                 160 


Val Arg Arg Leu Cys Glu Arg Glu Thr Pro Pro Asp Ala Leu Ile Leu 
                165                 170                 175     


Glu Ser Pro Phe Thr Asn Ile Arg Glu Glu Ala Lys Ser His Pro Phe 
            180                 185                 190         


Ser Val Ile Tyr Arg Tyr Phe Pro Gly Phe Asp Trp Phe Phe Leu Asp 
        195                 200                 205             


Pro Ile Thr Ser Ser Gly Ile Lys Phe Ala Asn Asp Glu Asn Val Lys 
    210                 215                 220                 


His Ile Ser Cys Pro Leu Leu Ile Leu His Ala Glu Asp Asp Pro Val 
225                 230                 235                 240 


Val Pro Phe Gln Leu Gly Arg Lys Leu Tyr Ser Ile Ala Ala Pro Ala 
                245                 250                 255     


Arg Ser Phe Arg Asp Phe Lys Val Gln Phe Val Pro Phe His Ser Asp 
            260                 265                 270         


Leu Gly Tyr Arg His Lys Tyr Ile Tyr Lys Ser Pro Glu Leu Pro Arg 
        275                 280                 285             


Ile Leu Arg Pro Gln Gln Gly Pro Gly Ser Ser Pro Asp Pro Ser Met 
    290                 295                 300                 


Trp Ser Glu Leu Val 
305                 


<210>  2650
<211>  632
<212>  PRT
<213>  Homo Sapiens

<400>  2650

Gln Lys Leu Asp Asp Val Asp Pro Leu Val Ala Thr Asn Phe Gly Lys 
1               5                   10                  15      


Ile Arg Gly Ile Lys Lys Glu Leu Asn Asn Glu Ile Leu Gly Pro Val 
            20                  25                  30          


Ile Gln Phe Leu Gly Val Pro Tyr Ala Ala Pro Pro Thr Gly Glu Arg 
        35                  40                  45              


Arg Phe Gln Pro Pro Glu Pro Pro Ser Pro Trp Ser Asp Ile Arg Asn 
    50                  55                  60                  


Ala Thr Gln Phe Ala Pro Val Cys Pro Gln Asn Ile Ile Asp Gly Arg 
65                  70                  75                  80  


Leu Pro Glu Val Met Leu Pro Val Trp Phe Thr Asn Asn Leu Asp Val 
                85                  90                  95      


Val Ser Ser Tyr Val Gln Asp Gln Ser Glu Asp Cys Leu Tyr Leu Asn 
            100                 105                 110         


Ile Tyr Val Pro Thr Glu Asp Asp Ile Arg Asp Ser Gly Gly Pro Lys 
        115                 120                 125             


Pro Val Met Val Tyr Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly 
    130                 135                 140                 


Asn Leu Tyr Asp Gly Ser Val Leu Ala Ser Tyr Gly Asn Val Ile Val 
145                 150                 155                 160 


Ile Thr Val Asn Tyr Arg Leu Gly Val Leu Gly Phe Leu Ser Thr Gly 
                165                 170                 175     


Asp Gln Ala Ala Lys Gly Asn Tyr Gly Leu Leu Asp Leu Ile Gln Ala 
            180                 185                 190         


Leu Arg Trp Thr Ser Glu Asn Ile Gly Phe Phe Gly Gly Asp Pro Leu 
        195                 200                 205             


Arg Ile Thr Val Phe Gly Ser Gly Ala Gly Gly Ser Cys Val Asn Leu 
    210                 215                 220                 


Leu Thr Leu Ser His Tyr Ser Glu Gly Asn Arg Trp Ser Asn Ser Thr 
225                 230                 235                 240 


Lys Gly Leu Phe Gln Arg Ala Ile Ala Gln Ser Gly Thr Ala Leu Ser 
                245                 250                 255     


Ser Trp Ala Val Ser Phe Gln Pro Ala Lys Tyr Ala Arg Met Leu Ala 
            260                 265                 270         


Thr Lys Val Gly Cys Asn Val Ser Asp Thr Val Glu Leu Val Glu Cys 
        275                 280                 285             


Leu Gln Lys Lys Pro Tyr Lys Glu Leu Val Asp Gln Asp Ile Gln Pro 
    290                 295                 300                 


Ala Arg Tyr His Ile Ala Phe Gly Pro Val Ile Asp Gly Asp Val Ile 
305                 310                 315                 320 


Pro Asp Asp Pro Gln Ile Leu Met Glu Gln Gly Glu Phe Leu Asn Tyr 
                325                 330                 335     


Asp Ile Met Leu Gly Val Asn Gln Gly Glu Gly Leu Lys Phe Val Glu 
            340                 345                 350         


Asn Ile Val Asp Ser Asp Asp Gly Ile Ser Ala Ser Asp Phe Asp Phe 
        355                 360                 365             


Ala Val Ser Asn Phe Val Asp Asn Leu Tyr Gly Tyr Pro Glu Gly Lys 
    370                 375                 380                 


Asp Val Leu Arg Glu Thr Ile Lys Phe Met Tyr Thr Asp Trp Ala Asp 
385                 390                 395                 400 


Arg His Asn Pro Glu Thr Arg Arg Lys Thr Leu Leu Ala Leu Phe Thr 
                405                 410                 415     


Asp His Gln Trp Val Ala Pro Ala Val Ala Thr Ala Asp Leu His Ser 
            420                 425                 430         


Asn Phe Gly Ser Pro Thr Tyr Phe Tyr Ala Phe Tyr His His Cys Gln 
        435                 440                 445             


Thr Asp Gln Val Pro Ala Trp Ala Asp Ala Ala His Gly Asp Glu Val 
    450                 455                 460                 


Pro Tyr Val Leu Gly Ile Pro Met Ile Gly Pro Thr Glu Leu Phe Pro 
465                 470                 475                 480 


Cys Asn Phe Ser Lys Asn Asp Val Met Leu Ser Ala Val Val Met Thr 
                485                 490                 495     


Tyr Trp Thr Asn Phe Ala Lys Thr Gly Asp Pro Asn Gln Pro Val Pro 
            500                 505                 510         


Gln Asp Thr Lys Phe Ile His Thr Lys Pro Asn Arg Phe Glu Glu Val 
        515                 520                 525             


Ala Trp Thr Arg Tyr Ser Gln Lys Asp Gln Leu Tyr Leu His Ile Gly 
    530                 535                 540                 


Leu Lys Pro Arg Val Lys Glu His Tyr Arg Ala Asn Lys Val Asn Leu 
545                 550                 555                 560 


Trp Leu Glu Leu Val Pro His Leu His Asn Leu Asn Asp Ile Ser Gln 
                565                 570                 575     


Tyr Thr Ser Thr Thr Thr Lys Val Pro Ser Thr Asp Ile Thr Phe Arg 
            580                 585                 590         


Pro Thr Arg Lys Asn Ser Val Pro Val Thr Ser Ala Phe Pro Thr Ala 
        595                 600                 605             


Lys Gln Asp Asp Pro Lys Gln Gln Pro Ser Pro Phe Ser Val Asp Gln 
    610                 615                 620                 


Arg Asp Tyr Ser Thr Glu Leu Ser 
625                 630         


<210>  2651
<211>  713
<212>  PRT
<213>  Homo Sapiens

<400>  2651

Ala Ser Glu Ala Pro Ser Pro Pro Arg Ser Pro Pro Pro Pro Thr Ser 
1               5                   10                  15      


Pro Glu Pro Glu Leu Ala Gln Leu Arg Arg Lys Val Glu Lys Leu Glu 
            20                  25                  30          


Arg Glu Leu Arg Ser Cys Lys Arg Gln Val Arg Glu Ile Glu Lys Leu 
        35                  40                  45              


Leu His His Thr Glu Arg Leu Tyr Gln Asn Ala Glu Ser Asn Asn Gln 
    50                  55                  60                  


Glu Leu Arg Thr Gln Val Glu Glu Leu Ser Lys Ile Leu Gln Arg Gly 
65                  70                  75                  80  


Arg Asn Glu Asp Asn Lys Lys Ser Asp Val Glu Val Gln Thr Glu Asn 
                85                  90                  95      


His Ala Pro Trp Ser Ile Ser Asp Tyr Phe Tyr Gln Thr Tyr Tyr Asn 
            100                 105                 110         


Asp Val Ser Leu Pro Asn Lys Val Thr Glu Leu Ser Asp Gln Gln Asp 
        115                 120                 125             


Gln Ala Ile Glu Thr Ser Ile Leu Asn Ser Lys Asp His Leu Gln Val 
    130                 135                 140                 


Glu Asn Asp Ala Tyr Pro Gly Thr Asp Arg Thr Glu Asn Val Lys Tyr 
145                 150                 155                 160 


Arg Gln Val Asp His Phe Ala Ser Asn Ser Gln Glu Pro Ala Ser Ala 
                165                 170                 175     


Leu Ala Thr Glu Asp Thr Ser Leu Glu Gly Ser Ser Leu Ala Glu Ser 
            180                 185                 190         


Leu Arg Ala Ala Ala Glu Ala Ala Val Ser Gln Thr Gly Phe Ser Tyr 
        195                 200                 205             


Asp Glu Asn Thr Gly Leu Tyr Phe Asp His Ser Thr Gly Phe Tyr Tyr 
    210                 215                 220                 


Asp Ser Glu Asn Gln Leu Tyr Tyr Asp Pro Ser Thr Gly Ile Tyr Tyr 
225                 230                 235                 240 


Tyr Cys Asp Val Glu Ser Gly Arg Tyr Gln Phe His Ser Arg Val Asp 
                245                 250                 255     


Leu Gln Pro Tyr Pro Thr Ser Ser Thr Lys Gln Ser Lys Asp Lys Lys 
            260                 265                 270         


Leu Lys Lys Lys Arg Lys Asp Pro Asp Ser Ser Ala Thr Asn Glu Glu 
        275                 280                 285             


Lys Asp Leu Asn Ser Glu Asp Gln Lys Ala Phe Ser Val Glu His Thr 
    290                 295                 300                 


Ser Cys Asn Glu Glu Glu Asn Phe Ala Asn Met Lys Lys Lys Ala Lys 
305                 310                 315                 320 


Ile Gly Ile His His Lys Asn Ser Pro Pro Lys Val Thr Val Pro Thr 
                325                 330                 335     


Ser Gly Asn Thr Ile Glu Ser Pro Leu His Glu Asn Ile Ser Asn Ser 
            340                 345                 350         


Thr Ser Phe Lys Asp Glu Lys Ile Met Glu Thr Asp Ser Glu Pro Glu 
        355                 360                 365             


Glu Gly Glu Ile Thr Asp Ser Gln Thr Glu Asp Ser Tyr Asp Glu Ala 
    370                 375                 380                 


Ile Thr Ser Glu Gly Asn Val Thr Ala Glu Asp Ser Glu Asp Glu Asp 
385                 390                 395                 400 


Glu Asp Lys Ile Trp Pro Pro Cys Ile Arg Val Ile Val Ile Arg Ser 
                405                 410                 415     


Pro Val Leu Gln Ile Gly Ser Leu Phe Ile Ile Thr Ala Val Asn Pro 
            420                 425                 430         


Ala Thr Ile Gly Arg Glu Lys Asp Met Glu His Thr Leu Arg Ile Pro 
        435                 440                 445             


Glu Val Gly Val Ser Lys Phe His Ala Glu Ile Tyr Phe Asp His Asp 
    450                 455                 460                 


Leu Gln Ser Tyr Val Leu Val Asp Gln Gly Ser Gln Asn Gly Thr Ile 
465                 470                 475                 480 


Val Asn Gly Lys Gln Ile Leu Gln Pro Lys Thr Lys Cys Asp Pro Tyr 
                485                 490                 495     


Val Leu Glu His Gly Asp Glu Val Lys Ile Gly Glu Thr Val Leu Ser 
            500                 505                 510         


Phe His Ile His Pro Gly Ser Asp Thr Cys Asp Gly Cys Glu Arg Gly 
        515                 520                 525             


Gln Val Arg Ala His Leu Arg Leu Asp Lys Lys Asp Glu Ser Phe Val 
    530                 535                 540                 


Gly Pro Thr Leu Ser Lys Glu Glu Lys Glu Leu Glu Gly Arg Lys Glu 
545                 550                 555                 560 


Leu Lys Lys Ile Arg Val Lys Tyr Gly Leu Gln Asn Thr Glu Tyr Glu 
                565                 570                 575     


Asp Glu Lys Thr Leu Lys Asn Pro Lys Tyr Lys Asp Arg Ala Gly Lys 
            580                 585                 590         


Arg Arg Glu Gln Val Gly Ser Glu Gly Thr Phe Gln Arg Asp Asp Ala 
        595                 600                 605             


Pro Ala Ser Val His Ser Glu Ile Thr Asp Ser Asn Lys Gly Arg Lys 
    610                 615                 620                 


Leu Leu Glu Lys Met Gly Trp Lys Lys Gly Glu Gly Leu Gly Lys Asp 
625                 630                 635                 640 


Gly Gly Gly Met Lys Thr Pro Ile Gln Leu Gln Leu Arg Arg Thr His 
                645                 650                 655     


Ala Gly Leu Gly Thr Gly Lys Pro Ser Ser Phe Glu Asp Val His Leu 
            660                 665                 670         


Leu Gln Asn Lys Asn Lys Lys Asn Trp Asp Lys Ala Arg Glu Arg Phe 
        675                 680                 685             


Thr Glu Asn Phe Pro Glu Thr Lys Pro Gln Lys Asp Asp Pro Gly Thr 
    690                 695                 700                 


Met Pro Trp Val Lys Gly Thr Leu Glu 
705                 710             


<210>  2652
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  2652

Lys Glu Asn Gln Asp Ile Asn Thr Thr Gln Asn Ile Ala Glu Val Phe 
1               5                   10                  15      


Lys Thr Met Glu Asn Lys Pro Ile Ser Leu Glu Ser Glu Ala Asn Leu 
            20                  25                  30          


Asn Ser Asp Lys Glu Asn Ile Thr Thr Ser Asn Leu Lys Ala Ser His 
        35                  40                  45              


Ser Pro Pro Leu Asn Leu Pro Asn Asn Ser His Gly Ile Thr Asp Phe 
    50                  55                  60                  


Ser Ser Asn Ser Ser Ala Glu His Ser Leu Gly Ser Leu Lys Pro Thr 
65                  70                  75                  80  


Ser Thr Ile Ser Thr Ser Pro Pro Leu Ile His Ser Phe Val Ser Lys 
                85                  90                  95      


Val Pro Trp Asn Ala Pro Ile Ala Asp Glu Asp Leu Leu Pro Ile Ser 
            100                 105                 110         


Ala His Pro Asn Ala Thr Pro Ala Leu Ser Ser Glu Asn Phe Thr Trp 
        115                 120                 125             


Ser Leu Val Asn Asp Thr Val Lys Thr Pro Asp Asn Ser Ser Ile Thr 
    130                 135                 140                 


Val Ser Ile Leu Ser Ser Glu Pro Thr Ser Pro Ser Val Thr Pro Leu 
145                 150                 155                 160 


Ile Val Glu Pro Ser Gly Trp Leu Thr Thr Asn Ser Asp Ser Phe Thr 
                165                 170                 175     


Gly Phe Ile Pro Tyr Gln Glu Lys Thr Thr Leu Gln Pro Thr Leu Lys 
            180                 185                 190         


Phe Thr Asn Asn Ser Lys Leu Phe Pro Asn Thr Ser Asp Pro Gln Lys 
        195                 200                 205             


Glu Asn Arg Asn Thr 
    210             


<210>  2653
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  2653

Ala Asn His His Lys Ala His His Val Lys Thr Gly Thr Cys Glu Val 
1               5                   10                  15      


Val Ala Leu His Arg Tyr Cys Asn Lys Asn Lys Ile Glu Glu Arg Ser 
            20                  25                  30          


Gln Thr Val Lys Tyr Ser Cys Phe Pro Gly Gln Val Ala Gly Thr Thr 
        35                  40                  45              


Arg Ala Ala Pro Ser Cys Val Asp Ala Ser Ile Val Glu Gln Lys Trp 
    50                  55                  60                  


Trp Cys His Met Gln Pro Cys Leu Glu Gly Glu Glu Cys Lys Val Leu 
65                  70                  75                  80  


Pro Asp Arg Lys Gly Trp Ser Cys Ser Ser Gly Asn Lys Val Lys Thr 
                85                  90                  95      


Thr Arg Val Thr His 
            100     


<210>  2654
<211>  397
<212>  PRT
<213>  Homo Sapiens

<400>  2654

Leu Ile Asp Gly Ser Glu Met Glu Trp Asp Phe Met Trp His Leu Arg 
1               5                   10                  15      


Lys Val Pro Arg Ile Val Ser Glu Arg Thr Phe His Leu Thr Ser Pro 
            20                  25                  30          


Ala Phe Glu Ala Asp Ala Lys Met Met Val Asn Thr Val Cys Gly Ile 
        35                  40                  45              


Glu Cys Gln Lys Glu Leu Pro Thr Pro Ser Leu Ser Glu Leu Glu Asp 
    50                  55                  60                  


Tyr Leu Ser Tyr Glu Thr Val Phe Glu Asn Gly Thr Arg Thr Leu Thr 
65                  70                  75                  80  


Arg Val Lys Val Gln Asp Leu Val Leu Glu Pro Thr Gln Asn Ile Thr 
                85                  90                  95      


Thr Lys Gly Val Ser Val Arg Arg Lys Arg Gln Val Tyr Gly Thr Asp 
            100                 105                 110         


Ser Arg Phe Ser Ile Leu Asp Lys Arg Phe Leu Thr Asn Phe Pro Phe 
        115                 120                 125             


Ser Thr Ala Val Lys Leu Ser Thr Gly Cys Ser Gly Ile Leu Ile Ser 
    130                 135                 140                 


Pro Gln His Val Leu Thr Ala Ala His Cys Val His Asp Gly Lys Asp 
145                 150                 155                 160 


Tyr Val Lys Gly Ser Lys Lys Leu Arg Val Gly Leu Leu Lys Met Arg 
                165                 170                 175     


Asn Lys Ser Gly Gly Lys Lys Arg Arg Gly Ser Lys Arg Ser Arg Arg 
            180                 185                 190         


Glu Ala Ser Gly Gly Asp Gln Arg Glu Gly Thr Arg Glu His Leu Gln 
        195                 200                 205             


Glu Arg Ala Lys Gly Gly Arg Arg Arg Lys Lys Ser Gly Arg Gly Gln 
    210                 215                 220                 


Arg Ile Ala Glu Gly Arg Pro Ser Phe Gln Trp Thr Arg Val Lys Asn 
225                 230                 235                 240 


Thr His Ile Pro Lys Gly Trp Ala Arg Gly Gly Met Gly Asp Ala Thr 
                245                 250                 255     


Leu Asp Tyr Asp Tyr Ala Leu Leu Glu Leu Lys Arg Ala His Lys Lys 
            260                 265                 270         


Lys Tyr Met Glu Leu Gly Ile Ser Pro Thr Ile Lys Lys Met Pro Gly 
        275                 280                 285             


Gly Met Ile His Phe Ser Gly Phe Asp Asn Asp Arg Ala Asp Gln Leu 
    290                 295                 300                 


Val Tyr Arg Phe Cys Ser Val Ser Asp Glu Ser Asn Asp Leu Leu Tyr 
305                 310                 315                 320 


Gln Tyr Cys Asp Ala Glu Ser Gly Ser Thr Gly Ser Gly Val Tyr Leu 
                325                 330                 335     


Arg Leu Lys Asp Pro Asp Lys Lys Asn Trp Lys Arg Lys Ile Ile Ala 
            340                 345                 350         


Val Tyr Ser Gly His Gln Trp Val Asp Val His Gly Val Gln Lys Asp 
        355                 360                 365             


Tyr Asn Val Ala Val Arg Ile Thr Pro Leu Lys Tyr Ala Gln Ile Cys 
    370                 375                 380                 


Leu Trp Ile His Gly Asn Asp Ala Asn Cys Ala Tyr Gly 
385                 390                 395         


<210>  2655
<211>  731
<212>  PRT
<213>  Homo Sapiens

<400>  2655

Gln Gly Ala Ala Leu Glu Asp Pro Asp Tyr Tyr Gly Gln Glu Ile Trp 
1               5                   10                  15      


Ser Arg Glu Pro Tyr Tyr Ala Arg Pro Glu Pro Glu Leu Glu Thr Phe 
            20                  25                  30          


Ser Pro Pro Leu Pro Ala Gly Pro Gly Glu Glu Trp Glu Arg Arg Pro 
        35                  40                  45              


Gln Glu Pro Arg Pro Pro Lys Arg Ala Thr Lys Pro Lys Lys Ala Pro 
    50                  55                  60                  


Lys Arg Glu Lys Ser Ala Pro Glu Pro Pro Pro Pro Gly Lys His Ser 
65                  70                  75                  80  


Asn Lys Lys Val Met Arg Thr Lys Ser Ser Glu Lys Ala Ala Asn Asp 
                85                  90                  95      


Asp His Ser Val Arg Val Ala Arg Glu Asp Val Arg Glu Ser Cys Pro 
            100                 105                 110         


Pro Leu Gly Leu Glu Thr Leu Lys Ile Thr Asp Phe Gln Leu His Ala 
        115                 120                 125             


Ser Thr Val Lys Arg Tyr Gly Leu Gly Ala His Arg Gly Arg Leu Asn 
    130                 135                 140                 


Ile Gln Ala Gly Ile Asn Glu Asn Asp Phe Tyr Asp Gly Ala Trp Cys 
145                 150                 155                 160 


Ala Gly Arg Asn Asp Leu Gln Gln Trp Ile Glu Val Asp Ala Arg Arg 
                165                 170                 175     


Leu Thr Arg Phe Thr Gly Val Ile Thr Gln Gly Arg Asn Ser Leu Trp 
            180                 185                 190         


Leu Ser Asp Trp Val Thr Ser Tyr Lys Val Met Val Ser Asn Asp Ser 
        195                 200                 205             


His Thr Trp Val Thr Val Lys Asn Gly Ser Gly Asp Met Ile Phe Glu 
    210                 215                 220                 


Gly Asn Ser Glu Lys Glu Ile Pro Val Leu Asn Glu Leu Pro Val Pro 
225                 230                 235                 240 


Met Val Ala Arg Tyr Ile Arg Ile Asn Pro Gln Ser Trp Phe Asp Asn 
                245                 250                 255     


Gly Ser Ile Cys Met Arg Met Glu Ile Leu Gly Cys Pro Leu Pro Asp 
            260                 265                 270         


Pro Asn Asn Tyr Tyr His Arg Arg Asn Glu Met Thr Thr Thr Asp Asp 
        275                 280                 285             


Leu Asp Phe Lys His His Asn Tyr Lys Glu Met Arg Gln Leu Met Lys 
    290                 295                 300                 


Val Val Asn Glu Met Cys Pro Asn Ile Thr Arg Ile Tyr Asn Ile Gly 
305                 310                 315                 320 


Lys Ser His Gln Gly Leu Lys Leu Tyr Ala Val Glu Ile Ser Asp His 
                325                 330                 335     


Pro Gly Glu His Glu Val Gly Glu Pro Glu Phe His Tyr Ile Ala Gly 
            340                 345                 350         


Ala His Gly Asn Glu Val Leu Gly Arg Glu Leu Leu Leu Leu Leu Val 
        355                 360                 365             


Gln Phe Val Cys Gln Glu Tyr Leu Ala Arg Asn Ala Arg Ile Val His 
    370                 375                 380                 


Leu Val Glu Glu Thr Arg Ile His Val Leu Pro Ser Leu Asn Pro Asp 
385                 390                 395                 400 


Gly Tyr Glu Lys Ala Tyr Glu Gly Gly Ser Glu Leu Gly Gly Trp Ser 
                405                 410                 415     


Leu Gly Arg Trp Thr His Asp Gly Ile Asp Ile Asn Asn Asn Phe Pro 
            420                 425                 430         


Asp Leu Asn Thr Leu Leu Trp Glu Ala Glu Asp Arg Gln Asn Val Pro 
        435                 440                 445             


Arg Lys Val Pro Asn His Tyr Ile Ala Ile Pro Glu Trp Phe Leu Ser 
    450                 455                 460                 


Glu Asn Ala Thr Val Ala Ala Glu Thr Arg Ala Val Ile Ala Trp Met 
465                 470                 475                 480 


Glu Lys Ile Pro Phe Val Leu Gly Gly Asn Leu Gln Gly Gly Glu Leu 
                485                 490                 495     


Val Val Ala Tyr Pro Tyr Asp Leu Val Arg Ser Pro Trp Lys Thr Gln 
            500                 505                 510         


Glu His Thr Pro Thr Pro Asp Asp His Val Phe Arg Trp Leu Ala Tyr 
        515                 520                 525             


Ser Tyr Ala Ser Thr His Arg Leu Met Thr Asp Ala Arg Arg Arg Val 
    530                 535                 540                 


Cys His Thr Glu Asp Phe Gln Lys Glu Glu Gly Thr Val Asn Gly Ala 
545                 550                 555                 560 


Ser Trp His Thr Val Ala Gly Ser Leu Asn Asp Phe Ser Tyr Leu His 
                565                 570                 575     


Thr Asn Cys Phe Glu Leu Ser Ile Tyr Val Gly Cys Asp Lys Tyr Pro 
            580                 585                 590         


His Glu Ser Gln Leu Pro Glu Glu Trp Glu Asn Asn Arg Glu Ser Leu 
        595                 600                 605             


Ile Val Phe Met Glu Gln Val His Arg Gly Ile Lys Gly Leu Val Arg 
    610                 615                 620                 


Asp Ser His Gly Lys Gly Ile Pro Asn Ala Ile Ile Ser Val Glu Gly 
625                 630                 635                 640 


Ile Asn His Asp Ile Arg Thr Ala Asn Asp Gly Asp Tyr Trp Arg Leu 
                645                 650                 655     


Leu Asn Pro Gly Glu Tyr Val Val Thr Ala Lys Ala Glu Gly Phe Thr 
            660                 665                 670         


Ala Ser Thr Lys Asn Cys Met Val Gly Tyr Asp Met Gly Ala Thr Arg 
        675                 680                 685             


Cys Asp Phe Thr Leu Ser Lys Thr Asn Met Ala Arg Ile Arg Glu Ile 
    690                 695                 700                 


Met Glu Lys Phe Gly Lys Gln Pro Val Ser Leu Pro Ala Arg Arg Leu 
705                 710                 715                 720 


Lys Leu Arg Gly Arg Lys Arg Arg Gln Arg Gly 
                725                 730     


<210>  2656
<211>  283
<212>  PRT
<213>  Homo Sapiens

<400>  2656

Ser Glu Tyr Asp Tyr Val Ser Phe Gln Ser Asp Ile Gly Pro Tyr Gln 
1               5                   10                  15      


Ser Gly Arg Phe Tyr Thr Lys Pro Pro Gln Cys Val Asp Ile Pro Ala 
            20                  25                  30          


Asp Leu Arg Leu Cys His Asn Val Gly Tyr Lys Lys Met Val Leu Pro 
        35                  40                  45              


Asn Leu Leu Glu His Glu Thr Met Ala Glu Val Lys Gln Gln Ala Ser 
    50                  55                  60                  


Ser Trp Val Pro Leu Leu Asn Lys Asn Cys His Ala Gly Thr Gln Val 
65                  70                  75                  80  


Phe Leu Cys Ser Leu Phe Ala Pro Val Cys Leu Asp Arg Pro Ile Tyr 
                85                  90                  95      


Pro Cys Arg Trp Leu Cys Glu Ala Val Arg Asp Ser Cys Glu Pro Val 
            100                 105                 110         


Met Gln Phe Phe Gly Phe Tyr Trp Pro Glu Met Leu Lys Cys Asp Lys 
        115                 120                 125             


Phe Pro Glu Gly Asp Val Cys Ile Ala Met Thr Pro Pro Asn Ala Thr 
    130                 135                 140                 


Glu Ala Ser Lys Pro Gln Gly Thr Thr Val Cys Pro Pro Cys Asp Asn 
145                 150                 155                 160 


Glu Leu Lys Ser Glu Ala Ile Ile Glu His Leu Cys Ala Ser Glu Phe 
                165                 170                 175     


Ala Leu Arg Met Lys Ile Lys Glu Val Lys Lys Glu Asn Gly Asp Lys 
            180                 185                 190         


Lys Ile Val Pro Lys Lys Lys Lys Pro Leu Lys Leu Gly Pro Ile Lys 
        195                 200                 205             


Lys Lys Asp Leu Lys Lys Leu Val Leu Tyr Leu Lys Asn Gly Ala Asp 
    210                 215                 220                 


Cys Pro Cys His Gln Leu Asp Asn Leu Ser His His Phe Leu Ile Met 
225                 230                 235                 240 


Gly Arg Lys Val Lys Ser Gln Tyr Leu Leu Thr Ala Ile His Lys Trp 
                245                 250                 255     


Asp Lys Lys Asn Lys Glu Phe Lys Asn Phe Met Lys Lys Met Lys Asn 
            260                 265                 270         


His Glu Cys Pro Thr Phe Gln Ser Val Phe Lys 
        275                 280             


<210>  2657
<211>  438
<212>  PRT
<213>  Homo Sapiens

<400>  2657

Ser Thr Pro Gly Thr Val Val Arg Leu Asn Lys Ala Ala Leu Ser Tyr 
1               5                   10                  15      


Val Ser Glu Ile Gly Lys Ala Pro Leu Gln Arg Ala Leu Gln Val Thr 
            20                  25                  30          


Val Pro His Phe Leu Asp Trp Ser Gly Glu Ala Leu Gln Pro Thr Arg 
        35                  40                  45              


Ile Arg Ile Leu Asn Val His Val Pro Arg Leu His Leu Lys Phe Ile 
    50                  55                  60                  


Ala Gly Phe Gly Val Arg Leu Leu Ala Ala Ala Asn Phe Thr Phe Lys 
65                  70                  75                  80  


Val Phe Arg Ala Pro Glu Pro Leu Glu Leu Thr Leu Pro Val Glu Leu 
                85                  90                  95      


Leu Ala Asp Thr Arg Val Thr Gln Ser Ser Ile Arg Thr Pro Val Val 
            100                 105                 110         


Ser Ile Ser Ala Cys Ser Leu Phe Ser Gly His Ala Asn Glu Phe Asp 
        115                 120                 125             


Gly Ser Asn Ser Thr Ser His Ala Leu Leu Val Leu Val Gln Lys His 
    130                 135                 140                 


Ile Lys Ala Val Leu Ser Asn Lys Leu Cys Leu Ser Ile Ser Asn Leu 
145                 150                 155                 160 


Val Gln Gly Val Asn Val His Leu Gly Thr Leu Ile Gly Leu Asn Pro 
                165                 170                 175     


Val Gly Pro Glu Ser Gln Ile Arg Tyr Ser Met Val Ser Val Pro Thr 
            180                 185                 190         


Val Thr Ser Asp Tyr Ile Ser Leu Glu Val Asn Ala Val Leu Phe Leu 
        195                 200                 205             


Leu Gly Lys Pro Ile Ile Leu Pro Thr Asp Ala Thr Pro Phe Val Leu 
    210                 215                 220                 


Pro Arg His Val Gly Thr Glu Gly Ser Met Ala Thr Gly Gly Leu Ser 
225                 230                 235                 240 


Gln Gln Leu Phe Asp Ser Ala Leu Leu Leu Leu Gln Lys Ala Gly Ala 
                245                 250                 255     


Leu Asn Leu Asp Ile Thr Gly Gln Leu Arg Ser Asp Asp Asn Leu Leu 
            260                 265                 270         


Asn Thr Ser Ala Leu Gly Arg Leu Ile Pro Glu Val Ala Arg Gln Phe 
        275                 280                 285             


Pro Glu Pro Met Pro Val Val Leu Lys Val Arg Leu Gly Ala Thr Pro 
    290                 295                 300                 


Val Ala Met Leu His Thr Asn Asn Ala Thr Leu Arg Leu Gln Pro Phe 
305                 310                 315                 320 


Val Glu Val Leu Ala Thr Ala Ser Asn Ser Ala Phe Gln Ser Leu Phe 
                325                 330                 335     


Ser Leu Asp Val Val Val Asn Leu Arg Leu Gln Leu Ser Val Ser Lys 
            340                 345                 350         


Val Lys Leu Gln Gly Thr Thr Ser Val Leu Gly Asp Val Gln Leu Thr 
        355                 360                 365             


Val Ala Ser Ser Asn Val Gly Phe Ile Asp Thr Asp Gln Val Arg Thr 
    370                 375                 380                 


Leu Met Gly Thr Val Phe Glu Lys Pro Leu Leu Asp His Leu Asn Ala 
385                 390                 395                 400 


Leu Leu Ala Met Gly Ile Ala Leu Pro Gly Val Val Asn Leu His Tyr 
                405                 410                 415     


Val Ala Pro Glu Ile Phe Val Tyr Glu Gly Tyr Val Val Ile Ser Ser 
            420                 425                 430         


Gly Leu Phe Tyr Gln Ser 
        435             


<210>  2658
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  2658

Ser Leu Ser Gly Tyr Asn Tyr Glu Val Tyr His Ser Leu Glu Glu Ile 
1               5                   10                  15      


Gln Asn Trp Met His His Leu Asn Lys Thr His Ser Gly Leu Ile His 
            20                  25                  30          


Met Phe Ser Ile Gly Arg Ser Tyr Glu Gly Arg Cys Leu Phe Ile Leu 
        35                  40                  45              


Lys Leu Gly Arg Arg Ser Arg Leu Lys Arg Ala Val Trp Ile Asp Cys 
    50                  55                  60                  


Gly Ile His Ala Arg Glu Trp Ile Gly Pro Ala Phe Cys Gln Trp Phe 
65                  70                  75                  80  


Val Lys Glu Ala Leu Leu Thr Tyr Lys Ser Asp Pro Ala Met Arg Lys 
                85                  90                  95      


Met Leu Asn His Leu Tyr Phe Tyr Ile Met Pro Val Phe Asn Val Asp 
            100                 105                 110         


Gly Tyr His Phe Ser Trp Thr Asn Asp Arg Phe Trp Arg Lys Thr Arg 
        115                 120                 125             


Ser Arg Asn Ser Arg Phe Arg Cys Arg Gly Val Asp Ala Asn Arg Asn 
    130                 135                 140                 


Trp Lys Val Lys Trp Cys Asp Glu Gly Ala Ser Met His Pro Cys Asp 
145                 150                 155                 160 


Asp Thr Tyr Cys Gly Pro Phe Pro Glu Ser Glu Pro Glu Val Lys Ala 
                165                 170                 175     


Val Ala Asn Phe Leu Arg Lys His Arg Lys His Ile Arg Ala Tyr Leu 
            180                 185                 190         


Ser Phe His Ala Tyr Ala Gln Met Leu Leu Tyr Pro Tyr Ser Tyr Lys 
        195                 200                 205             


Tyr Ala Thr Ile Pro Asn Phe Arg Cys Val Glu Ser Ala Ala Tyr Lys 
    210                 215                 220                 


Ala Val Asn Ala Leu Gln Ser Val Tyr Gly Val Arg Tyr Arg Tyr Gly 
225                 230                 235                 240 


Pro Ala Ser Thr Thr Leu Tyr Val Ser Ser Gly Ser Ser Met Asp Trp 
                245                 250                 255     


Ala Tyr Lys Asn Gly Ile Pro Tyr Ala Phe Ala Phe Glu Leu Arg Asp 
            260                 265                 270         


Thr Gly Tyr Phe Gly Phe Leu Leu Pro Glu Met Leu Ile Lys Pro Thr 
        275                 280                 285             


Cys Thr Glu Thr Met Leu Ala Val Lys Asn Ile Thr Met His Leu Leu 
    290                 295                 300                 


Lys Lys Cys Pro 
305             


<210>  2659
<211>  407
<212>  PRT
<213>  Homo Sapiens

<400>  2659

Asn His Ala His Ala Pro Gly Thr Ala Pro Pro Pro Val Val Ser Thr 
1               5                   10                  15      


Gly Ala Ala Ser Ala Asn Ser Ala Val Val Thr Val Glu Arg Ala Asp 
            20                  25                  30          


Ser Ser His Leu Ser Ile Leu Ile Asp Pro Arg Cys Pro Asp Leu Thr 
        35                  40                  45              


Asp Ser Phe Ala Arg Leu Glu Ser Ala Gln Ala Ser Val Leu Gln Ala 
    50                  55                  60                  


Leu Thr Glu His Gln Ala Gln Pro Arg Leu Val Gly Asp Gln Glu Gln 
65                  70                  75                  80  


Glu Leu Leu Asp Thr Leu Ala Asp Gln Leu Pro Arg Leu Leu Ala Arg 
                85                  90                  95      


Ala Ser Glu Leu Gln Thr Glu Cys Met Gly Leu Arg Lys Gly His Gly 
            100                 105                 110         


Thr Leu Gly Gln Gly Leu Ser Ala Leu Gln Ser Glu Gln Gly Arg Leu 
        115                 120                 125             


Ile Gln Leu Leu Ser Glu Ser Gln Gly His Met Ala His Leu Val Asn 
    130                 135                 140                 


Ser Val Ser Asp Ile Leu Asp Ala Leu Gln Arg Asp Arg Gly Leu Gly 
145                 150                 155                 160 


Arg Pro Arg Asn Lys Ala Asp Leu Gln Arg Ala Pro Ala Arg Gly Thr 
                165                 170                 175     


Arg Pro Arg Gly Cys Ala Thr Gly Ser Arg Pro Arg Asp Cys Leu Asp 
            180                 185                 190         


Val Leu Leu Ser Gly Gln Gln Asp Asp Gly Val Tyr Ser Val Phe Pro 
        195                 200                 205             


Thr His Tyr Pro Ala Gly Phe Gln Val Tyr Cys Asp Met Arg Thr Asp 
    210                 215                 220                 


Gly Gly Gly Trp Thr Val Phe Gln Arg Arg Glu Asp Gly Ser Val Asn 
225                 230                 235                 240 


Phe Phe Arg Gly Trp Asp Ala Tyr Arg Asp Gly Phe Gly Arg Leu Thr 
                245                 250                 255     


Gly Glu His Trp Leu Gly Leu Lys Arg Ile His Ala Leu Thr Thr Gln 
            260                 265                 270         


Ala Ala Tyr Glu Leu His Val Asp Leu Glu Asp Phe Glu Asn Gly Thr 
        275                 280                 285             


Ala Tyr Ala Arg Tyr Gly Ser Phe Gly Val Gly Leu Phe Ser Val Asp 
    290                 295                 300                 


Pro Glu Glu Asp Gly Tyr Pro Leu Thr Val Ala Asp Tyr Ser Gly Thr 
305                 310                 315                 320 


Ala Gly Asp Ser Leu Leu Lys His Ser Gly Met Arg Phe Thr Thr Lys 
                325                 330                 335     


Asp Arg Asp Ser Asp His Ser Glu Asn Asn Cys Ala Ala Phe Tyr Arg 
            340                 345                 350         


Gly Ala Trp Trp Tyr Arg Asn Cys His Thr Ser Asn Leu Asn Gly Gln 
        355                 360                 365             


Tyr Leu Arg Gly Ala His Ala Ser Tyr Ala Asp Gly Val Glu Trp Ser 
    370                 375                 380                 


Ser Trp Thr Gly Trp Gln Tyr Ser Leu Lys Phe Ser Glu Met Lys Ile 
385                 390                 395                 400 


Arg Pro Val Arg Glu Asp Arg 
                405         


<210>  2660
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  2660

Ser Pro Leu Ser Ala Ala Arg Ala Ala Leu Arg Val Tyr Ala Val Gly 
1               5                   10                  15      


Ala Ala Val Ile Leu Ala Gln Leu Leu Arg Arg Cys Arg Gly Gly Phe 
            20                  25                  30          


Leu Glu Pro Val Phe Pro Pro Arg Pro Asp Arg Val Ala Ile Val Thr 
        35                  40                  45              


Gly Gly Thr Asp Gly Ile Gly Tyr Ser Thr Ala Lys His Leu Ala Arg 
    50                  55                  60                  


Leu Gly Met His Val Ile Ile Ala Gly Asn Asn Asp Ser Lys Ala Lys 
65                  70                  75                  80  


Gln Val Val Ser Lys Ile Lys Glu Glu Thr Leu Asn Asp Lys Val Glu 
                85                  90                  95      


Phe Leu Tyr Cys Asp Leu Ala Ser Met Thr Ser Ile Arg Gln Phe Val 
            100                 105                 110         


Gln Lys Phe Lys Met Lys Lys Ile Pro Leu His Val Leu Ile Asn Asn 
        115                 120                 125             


Ala Gly Val Met Met Val Pro Gln Arg Lys Thr Arg Asp Gly Phe Glu 
    130                 135                 140                 


Glu His Phe Gly Leu Asn Tyr Leu Gly His Phe Leu Leu Thr Asn Leu 
145                 150                 155                 160 


Leu Leu Asp Thr Leu Lys Glu Ser Gly Ser Pro Gly His Ser Ala Arg 
                165                 170                 175     


Val Val Thr Val Ser Ser Ala Thr His Tyr Val Ala Glu Leu Asn Met 
            180                 185                 190         


Asp Asp Leu Gln Ser Ser Ala Cys Tyr Ser Pro His Ala Ala Tyr Ala 
        195                 200                 205             


Gln Ser Lys Leu Ala Leu Val Leu Phe Thr Tyr His Leu Gln Arg Leu 
    210                 215                 220                 


Leu Ala Ala Glu Gly Ser His Val Thr Ala Asn Val Val Asp Pro Gly 
225                 230                 235                 240 


Val Val Asn Thr Asp Leu Tyr Lys His Val Phe Trp Ala Thr Arg Leu 
                245                 250                 255     


Ala Lys Lys Leu Leu Gly Trp Leu Leu Phe Lys Thr Pro Asp Glu Gly 
            260                 265                 270         


Ala Trp Thr Ser Ile Tyr Ala Ala Val Thr Pro Glu Leu Glu Gly Val 
        275                 280                 285             


Gly Gly Arg Tyr Leu Tyr Asn Glu Lys Glu Thr Lys Ser Leu His Val 
    290                 295                 300                 


Thr Tyr Asn Gln Lys Leu Gln Gln Gln Leu Trp Ser Lys Ser Cys Glu 
305                 310                 315                 320 


Met Thr Gly Val Leu Asp Val Thr Leu 
                325                 


<210>  2661
<211>  73
<212>  PRT
<213>  Homo Sapiens

<400>  2661

Leu Tyr Phe Lys Ile His Asn Ala Leu Lys Ala Ala Lys Glu Pro Glu 
1               5                   10                  15      


Ala Val Ala Val Lys Asn His Asn Pro Asp Lys Val Trp Trp Ala Lys 
            20                  25                  30          


Asn Ser Gln Ala Lys Thr Ile Ala Thr Glu Ser Cys Pro Ala Leu Gln 
        35                  40                  45              


Cys Cys Glu Gly Tyr Arg Met Cys Ala Ser Phe Asp Ser Leu Pro Pro 
    50                  55                  60                  


Cys Cys Cys Asp Ile Asn Glu Gly Leu 
65                  70              


<210>  2662
<211>  741
<212>  PRT
<213>  Homo Sapiens

<400>  2662

Leu Thr Pro Asp Glu Leu Thr Asn Ser Ser Glu Thr Arg Leu Ser Leu 
1               5                   10                  15      


Glu Asp Leu Phe Arg Lys Asp Phe Val Leu His Asp Pro Glu Ala Arg 
            20                  25                  30          


Trp Ile Asn Asp Thr Asp Val Val Tyr Lys Ser Glu Asn Gly His Val 
        35                  40                  45              


Ile Lys Leu Asn Ile Glu Thr Asn Ala Thr Thr Leu Leu Leu Glu Asn 
    50                  55                  60                  


Thr Thr Phe Val Thr Phe Lys Ala Ser Arg His Ser Val Ser Pro Asp 
65                  70                  75                  80  


Leu Lys Tyr Val Leu Leu Ala Tyr Asp Val Lys Gln Ile Phe His Tyr 
                85                  90                  95      


Ser Tyr Thr Ala Ser Tyr Val Ile Tyr Asn Ile His Thr Arg Glu Val 
            100                 105                 110         


Trp Glu Leu Asn Pro Pro Glu Val Glu Asp Ser Val Leu Gln Tyr Ala 
        115                 120                 125             


Ala Trp Gly Val Gln Gly Gln Gln Leu Ile Tyr Ile Phe Glu Asn Asn 
    130                 135                 140                 


Ile Tyr Tyr Gln Pro Asp Ile Lys Ser Ser Ser Leu Arg Leu Thr Ser 
145                 150                 155                 160 


Ser Gly Lys Glu Glu Ile Ile Phe Asn Gly Ile Ala Asp Trp Leu Tyr 
                165                 170                 175     


Glu Glu Glu Leu Leu His Ser His Ile Ala His Trp Trp Ser Pro Asp 
            180                 185                 190         


Gly Glu Arg Leu Ala Phe Leu Met Ile Asn Asp Ser Leu Val Pro Thr 
        195                 200                 205             


Met Val Ile Pro Arg Phe Thr Gly Ala Leu Tyr Pro Lys Gly Lys Gln 
    210                 215                 220                 


Tyr Pro Tyr Pro Lys Ala Gly Gln Met Asn Pro Thr Ile Lys Leu Tyr 
225                 230                 235                 240 


Val Val Asn Leu Tyr Gly Pro Thr His Thr Leu Glu Leu Met Pro Pro 
                245                 250                 255     


Asp Ser Phe Lys Ser Arg Glu Tyr Tyr Ile Thr Met Val Lys Trp Val 
            260                 265                 270         


Ser Asn Thr Lys Thr Val Val Arg Trp Leu Asn Arg Ala Gln Asn Ile 
        275                 280                 285             


Ser Ile Leu Thr Val Cys Glu Thr Thr Thr Gly Ala Cys Ser Lys Lys 
    290                 295                 300                 


Tyr Glu Met Thr Ser Asp Thr Trp Leu Ser Gln Gln Asn Glu Glu Pro 
305                 310                 315                 320 


Val Phe Ser Arg Asp Gly Ser Lys Phe Phe Met Thr Val Pro Val Lys 
                325                 330                 335     


Gln Gly Gly Arg Gly Glu Phe His His Ile Ala Met Phe Leu Ile Gln 
            340                 345                 350         


Ser Lys Ser Glu Gln Ile Thr Val Arg His Leu Thr Ser Gly Asn Trp 
        355                 360                 365             


Glu Val Ile Lys Ile Leu Ala Tyr Asp Glu Thr Thr Gln Lys Ile Tyr 
    370                 375                 380                 


Phe Leu Ser Thr Glu Ser Ser Pro Arg Gly Arg Gln Leu Tyr Ser Ala 
385                 390                 395                 400 


Ser Thr Glu Gly Leu Leu Asn Arg Gln Cys Ile Ser Cys Asn Phe Met 
                405                 410                 415     


Lys Glu Gln Cys Thr Tyr Phe Asp Ala Ser Phe Ser Pro Met Asn Gln 
            420                 425                 430         


His Phe Leu Leu Phe Cys Glu Gly Pro Arg Val Pro Val Val Ser Leu 
        435                 440                 445             


His Ser Thr Asp Asn Pro Ala Lys Tyr Phe Ile Leu Glu Ser Asn Ser 
    450                 455                 460                 


Met Leu Lys Glu Ala Ile Leu Lys Lys Lys Ile Gly Lys Pro Glu Ile 
465                 470                 475                 480 


Lys Ile Leu His Ile Asp Asp Tyr Glu Leu Pro Leu Gln Leu Ser Leu 
                485                 490                 495     


Pro Lys Asp Phe Met Asp Arg Asn Gln Tyr Ala Leu Leu Leu Ile Met 
            500                 505                 510         


Asp Glu Glu Pro Gly Gly Gln Leu Val Thr Asp Lys Phe His Ile Asp 
        515                 520                 525             


Trp Asp Ser Val Leu Ile Asp Met Asp Asn Val Ile Val Ala Arg Phe 
    530                 535                 540                 


Asp Gly Arg Gly Ser Gly Phe Gln Gly Leu Lys Ile Leu Gln Glu Ile 
545                 550                 555                 560 


His Arg Arg Leu Gly Ser Val Glu Val Lys Asp Gln Ile Thr Ala Val 
                565                 570                 575     


Lys Phe Leu Leu Lys Leu Pro Tyr Ile Asp Ser Lys Arg Leu Ser Ile 
            580                 585                 590         


Phe Gly Lys Gly Tyr Gly Gly Tyr Ile Ala Ser Met Ile Leu Lys Ser 
        595                 600                 605             


Asp Glu Lys Leu Phe Lys Cys Gly Ser Val Val Ala Pro Ile Thr Asp 
    610                 615                 620                 


Leu Lys Leu Tyr Ala Ser Ala Phe Ser Glu Arg Tyr Leu Gly Met Pro 
625                 630                 635                 640 


Ser Lys Glu Glu Ser Thr Tyr Gln Ala Ala Ser Val Leu His Asn Val 
                645                 650                 655     


His Gly Leu Lys Glu Glu Asn Ile Leu Ile Ile His Gly Thr Ala Asp 
            660                 665                 670         


Thr Lys Val His Phe Gln His Ser Ala Glu Leu Ile Lys His Leu Ile 
        675                 680                 685             


Lys Ala Gly Val Asn Tyr Thr Met Gln Val Tyr Pro Asp Glu Gly His 
    690                 695                 700                 


Asn Val Ser Glu Lys Ser Lys Tyr His Leu Tyr Ser Thr Ile Leu Lys 
705                 710                 715                 720 


Phe Phe Ser Asp Cys Leu Lys Glu Glu Ile Ser Val Leu Pro Gln Glu 
                725                 730                 735     


Pro Glu Glu Asp Glu 
            740     


<210>  2663
<211>  58
<212>  PRT
<213>  Homo Sapiens

<400>  2663

Gln Ile Tyr Pro Pro Leu Pro Glu Arg Thr Leu Pro Leu His Leu Asp 
1               5                   10                  15      


Ile Gln Gly Cys Asn Ser Thr Tyr Asn Glu Thr Asn Leu Met Thr Thr 
            20                  25                  30          


Thr Glu Met Pro Phe Thr Thr Ser Val Phe Gln Ile Tyr Asn Val Gln 
        35                  40                  45              


Arg Thr Pro Leu Met Asp Asn Trp Tyr Ser 
    50                  55              


<210>  2664
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2664

Gln Trp Lys Gln Ser Ser Tyr Ala Gly Asp Ala Ile Ile Thr Ala Val 
1               5                   10                  15      


Gly Leu Tyr Glu Gly Leu Trp Met Ser Cys Ala Ser Gln Ser Thr Gly 
            20                  25                  30          


Gln Val Gln Cys Lys Leu Tyr Asp Ser Leu Leu Ala Leu Asp Gly His 
        35                  40                  45              


Ile Gln Ser Ala Arg 
    50              


<210>  2665
<211>  937
<212>  PRT
<213>  Homo Sapiens

<400>  2665

Val Tyr Glu Asp Gln Val Gly Lys Phe Asp Trp Arg Gln Gln Tyr Val 
1               5                   10                  15      


Gly Lys Val Lys Phe Ala Ser Leu Glu Phe Ser Pro Gly Ser Lys Lys 
            20                  25                  30          


Leu Val Val Ala Thr Glu Lys Asn Val Ile Ala Ala Leu Asn Ser Arg 
        35                  40                  45              


Thr Gly Glu Ile Leu Trp Arg His Val Asp Lys Gly Thr Ala Glu Gly 
    50                  55                  60                  


Ala Val Asp Ala Met Leu Leu His Gly Gln Asp Val Ile Thr Val Ser 
65                  70                  75                  80  


Asn Gly Gly Arg Ile Met Arg Ser Trp Glu Thr Asn Ile Gly Gly Leu 
                85                  90                  95      


Asn Trp Glu Ile Thr Leu Asp Ser Gly Ser Phe Gln Ala Leu Gly Leu 
            100                 105                 110         


Val Gly Leu Gln Glu Ser Val Arg Tyr Ile Ala Val Leu Lys Lys Thr 
        115                 120                 125             


Thr Leu Ala Leu His His Leu Ser Ser Gly His Leu Lys Trp Val Glu 
    130                 135                 140                 


His Leu Pro Glu Ser Asp Ser Ile His Tyr Gln Met Val Tyr Ser Tyr 
145                 150                 155                 160 


Gly Ser Gly Val Val Trp Ala Leu Gly Val Val Pro Phe Ser His Val 
                165                 170                 175     


Asn Ile Val Lys Phe Asn Val Glu Asp Gly Glu Ile Val Gln Gln Val 
            180                 185                 190         


Arg Val Ser Thr Pro Trp Leu Gln His Leu Ser Gly Ala Cys Gly Val 
        195                 200                 205             


Val Asp Glu Ala Val Leu Val Cys Pro Asp Pro Ser Ser Arg Ser Leu 
    210                 215                 220                 


Gln Thr Leu Ala Leu Glu Thr Glu Trp Glu Leu Arg Gln Ile Pro Leu 
225                 230                 235                 240 


Gln Ser Leu Asp Leu Glu Phe Gly Ser Gly Phe Gln Pro Arg Val Leu 
                245                 250                 255     


Pro Thr Gln Pro Asn Pro Val Asp Ala Ser Arg Ala Gln Phe Phe Leu 
            260                 265                 270         


His Leu Ser Pro Ser His Tyr Ala Leu Leu Gln Tyr His Tyr Gly Thr 
        275                 280                 285             


Leu Ser Leu Leu Lys Asn Phe Pro Gln Thr Ala Leu Val Ser Phe Ala 
    290                 295                 300                 


Thr Thr Gly Glu Lys Thr Val Ala Ala Val Met Ala Cys Arg Asn Glu 
305                 310                 315                 320 


Val Gln Lys Ser Ser Ser Ser Glu Asp Gly Ser Met Gly Ser Phe Ser 
                325                 330                 335     


Glu Lys Ser Ser Ser Lys Asp Ser Leu Ala Cys Phe Asn Gln Thr Tyr 
            340                 345                 350         


Thr Ile Asn Leu Tyr Leu Val Glu Thr Gly Arg Arg Leu Leu Asp Thr 
        355                 360                 365             


Thr Ile Thr Phe Ser Leu Glu Gln Ser Gly Thr Arg Pro Glu Arg Leu 
    370                 375                 380                 


Tyr Ile Gln Val Phe Leu Lys Lys Asp Asp Ser Val Gly Tyr Arg Ala 
385                 390                 395                 400 


Leu Val Gln Thr Glu Asp His Leu Leu Leu Phe Leu Gln Gln Leu Ala 
                405                 410                 415     


Gly Lys Val Val Leu Trp Ser Arg Glu Glu Ser Leu Ala Glu Val Val 
            420                 425                 430         


Cys Leu Glu Met Val Asp Leu Pro Leu Thr Gly Ala Gln Ala Glu Leu 
        435                 440                 445             


Glu Gly Glu Phe Gly Lys Lys Ala Asp Gly Leu Leu Gly Met Phe Leu 
    450                 455                 460                 


Lys Arg Leu Ser Ser Gln Leu Ile Leu Leu Gln Ala Trp Thr Ser His 
465                 470                 475                 480 


Leu Trp Lys Met Phe Tyr Asp Ala Arg Lys Pro Arg Ser Gln Ile Lys 
                485                 490                 495     


Asn Glu Ile Asn Ile Asp Thr Leu Ala Arg Asp Glu Phe Asn Leu Gln 
            500                 505                 510         


Lys Met Met Val Met Val Thr Ala Ser Gly Lys Leu Phe Gly Ile Glu 
        515                 520                 525             


Ser Ser Ser Gly Thr Ile Leu Trp Lys Gln Tyr Leu Pro Asn Val Lys 
    530                 535                 540                 


Pro Asp Ser Ser Phe Lys Leu Met Val Gln Arg Thr Thr Ala His Phe 
545                 550                 555                 560 


Pro His Pro Pro Gln Cys Thr Leu Leu Val Lys Asp Lys Glu Ser Gly 
                565                 570                 575     


Met Ser Ser Leu Tyr Val Phe Asn Pro Ile Phe Gly Lys Trp Ser Gln 
            580                 585                 590         


Val Ala Pro Pro Val Leu Lys Arg Pro Ile Leu Gln Ser Leu Leu Leu 
        595                 600                 605             


Pro Val Met Asp Gln Asp Tyr Ala Lys Val Leu Leu Leu Ile Asp Asp 
    610                 615                 620                 


Glu Tyr Lys Val Thr Ala Phe Pro Ala Thr Arg Asn Val Leu Arg Gln 
625                 630                 635                 640 


Leu His Glu Leu Ala Pro Ser Ile Phe Phe Tyr Leu Val Asp Ala Glu 
                645                 650                 655     


Gln Gly Arg Leu Cys Gly Tyr Arg Leu Arg Lys Asp Leu Thr Thr Glu 
            660                 665                 670         


Leu Ser Trp Glu Leu Thr Ile Pro Pro Glu Val Gln Arg Ile Val Lys 
        675                 680                 685             


Val Lys Gly Lys Arg Ser Ser Glu His Val His Ser Gln Gly Arg Val 
    690                 695                 700                 


Met Gly Asp Arg Ser Val Leu Tyr Lys Ser Leu Asn Pro Asn Leu Leu 
705                 710                 715                 720 


Ala Val Val Thr Glu Ser Thr Asp Ala His His Glu Arg Thr Phe Ile 
                725                 730                 735     


Gly Ile Phe Leu Ile Asp Gly Val Thr Gly Arg Ile Ile His Ser Ser 
            740                 745                 750         


Val Gln Lys Lys Ala Lys Gly Pro Val His Ile Val His Ser Glu Asn 
        755                 760                 765             


Trp Val Val Tyr Gln Tyr Trp Asn Thr Lys Ala Arg Arg Asn Glu Phe 
    770                 775                 780                 


Thr Val Leu Glu Leu Tyr Glu Gly Thr Glu Gln Tyr Asn Ala Thr Ala 
785                 790                 795                 800 


Phe Ser Ser Leu Asp Arg Pro Gln Leu Pro Gln Val Leu Gln Gln Ser 
                805                 810                 815     


Tyr Ile Phe Pro Ser Ser Ile Ser Ala Met Glu Ala Thr Ile Thr Glu 
            820                 825                 830         


Arg Gly Ile Thr Ser Arg His Leu Leu Ile Gly Leu Pro Ser Gly Ala 
        835                 840                 845             


Ile Leu Ser Leu Pro Lys Ala Leu Leu Asp Pro Arg Arg Pro Glu Ile 
    850                 855                 860                 


Pro Thr Glu Gln Ser Arg Glu Glu Asn Leu Ile Pro Tyr Ser Pro Asp 
865                 870                 875                 880 


Val Gln Ile His Ala Glu Arg Phe Ile Asn Tyr Asn Gln Thr Val Ser 
                885                 890                 895     


Arg Met Arg Gly Ile Tyr Thr Ala Pro Ser Gly Leu Glu Ser Thr Cys 
            900                 905                 910         


Leu Val Val Ala Tyr Gly Leu Asp Ile Tyr Gln Thr Arg Val Tyr Pro 
        915                 920                 925             


Ser Lys Gln Phe Asp Val Leu Lys Asp 
    930                 935         


<210>  2666
<211>  564
<212>  PRT
<213>  Homo Sapiens

<400>  2666

Ser Pro Glu Val Asn Ala Gly Val Ser Ser Ile His Ile Thr Lys Pro 
1               5                   10                  15      


Val His Ile Leu Glu Glu Arg Ser Leu Leu Val Leu Thr Pro Ala Gly 
            20                  25                  30          


Leu Thr Gln Met Leu Asn Gln Thr Arg Phe Leu Met Val Leu Phe His 
        35                  40                  45              


Asn Pro Ser Ser Lys Gln Ser Arg Asn Leu Ala Glu Glu Leu Gly Lys 
    50                  55                  60                  


Ala Val Glu Ile Met Gly Lys Gly Lys Asn Gly Ile Gly Phe Gly Lys 
65                  70                  75                  80  


Val Asp Ile Thr Ile Glu Lys Glu Leu Gln Gln Glu Phe Gly Ile Thr 
                85                  90                  95      


Lys Ala Pro Glu Leu Lys Leu Phe Phe Glu Gly Asn Arg Ser Glu Pro 
            100                 105                 110         


Ile Ser Cys Lys Gly Val Val Glu Ser Ala Ala Leu Val Val Trp Leu 
        115                 120                 125             


Arg Arg Gln Ile Ser Gln Lys Ala Phe Leu Phe Asn Ser Ser Glu Gln 
    130                 135                 140                 


Val Ala Glu Phe Val Ile Ser Arg Pro Leu Val Ile Val Gly Phe Phe 
145                 150                 155                 160 


Gln Asp Leu Glu Glu Glu Val Ala Glu Leu Phe Tyr Asp Val Ile Lys 
                165                 170                 175     


Asp Phe Pro Glu Leu Thr Phe Gly Val Ile Thr Ile Gly Asn Val Ile 
            180                 185                 190         


Gly Arg Phe His Val Thr Leu Asp Ser Val Leu Val Phe Lys Lys Gly 
        195                 200                 205             


Lys Ile Val Asn Arg Gln Lys Leu Ile Asn Asp Ser Thr Asn Lys Gln 
    210                 215                 220                 


Glu Leu Asn Arg Val Ile Lys Gln His Leu Thr Asp Phe Val Ile Glu 
225                 230                 235                 240 


Tyr Asn Thr Glu Asn Lys Asp Leu Ile Ser Glu Leu His Ile Met Ser 
                245                 250                 255     


His Met Leu Leu Phe Val Ser Lys Ser Ser Glu Ser Tyr Gly Ile Ile 
            260                 265                 270         


Ile Gln His Tyr Lys Leu Ala Ser Lys Glu Phe Gln Asn Lys Ile Leu 
        275                 280                 285             


Phe Ile Leu Val Asp Ala Asp Glu Pro Arg Asn Gly Arg Val Phe Lys 
    290                 295                 300                 


Tyr Phe Arg Val Thr Glu Val Asp Ile Pro Ser Val Gln Ile Leu Asn 
305                 310                 315                 320 


Leu Ser Ser Asp Ala Arg Tyr Lys Met Pro Ser Asp Asp Ile Thr Tyr 
                325                 330                 335     


Glu Ser Leu Lys Lys Phe Gly Arg Ser Phe Leu Ser Lys Asn Ala Thr 
            340                 345                 350         


Lys His Gln Ser Ser Glu Glu Ile Pro Lys Tyr Trp Asp Gln Gly Leu 
        355                 360                 365             


Val Lys Gln Leu Val Gly Lys Asn Phe Asn Val Val Val Phe Asp Lys 
    370                 375                 380                 


Glu Lys Asp Val Phe Val Met Phe Tyr Ala Pro Trp Ser Lys Lys Cys 
385                 390                 395                 400 


Lys Met Leu Phe Pro Leu Leu Glu Glu Leu Gly Arg Lys Tyr Gln Asn 
                405                 410                 415     


His Ser Thr Ile Ile Ile Ala Lys Ile Asp Val Thr Ala Asn Asp Ile 
            420                 425                 430         


Gln Leu Met Tyr Leu Asp Arg Tyr Pro Phe Phe Arg Leu Phe Pro Ser 
        435                 440                 445             


Gly Ser Gln Gln Ala Val Leu Tyr Lys Gly Glu His Thr Leu Lys Gly 
    450                 455                 460                 


Phe Ser Asp Phe Leu Glu Ser His Ile Lys Thr Lys Ile Glu Asp Glu 
465                 470                 475                 480 


Asp Glu Leu Leu Ser Val Glu Gln Asn Glu Val Ile Glu Glu Glu Val 
                485                 490                 495     


Leu Ala Glu Glu Lys Glu Val Pro Met Met Arg Lys Gly Leu Pro Glu 
            500                 505                 510         


Gln Gln Ser Pro Glu Leu Glu Asn Met Thr Lys Tyr Val Ser Lys Leu 
        515                 520                 525             


Glu Glu Pro Ala Gly Lys Lys Lys Thr Ser Glu Glu Val Val Val Val 
    530                 535                 540                 


Val Ala Lys Pro Lys Gly Pro Pro Val Gln Lys Lys Lys Pro Lys Val 
545                 550                 555                 560 


Lys Glu Glu Leu 
                


<210>  2667
<211>  260
<212>  PRT
<213>  Homo Sapiens

<400>  2667

Met Ala Ser Ala Val Trp Gly Ser Ala Pro Trp Trp Gly Pro Pro Pro 
1               5                   10                  15      


Pro Ala Pro Ala Arg Pro Leu Thr Asp Ile Asp Phe Cys Ser Gly Ala 
            20                  25                  30          


Gln Leu Gln Glu Leu Thr Gln Leu Ile Gln Glu Leu Gly Val Gln Glu 
        35                  40                  45              


Ser Trp Ser Asp Gly Pro Lys Pro Gly Ala Asp Leu Leu Arg Ala Lys 
    50                  55                  60                  


Asp Phe Val Phe Ser Leu Leu Gly Leu Val His Arg Arg Asp Pro Arg 
65                  70                  75                  80  


Phe Pro Pro Gln Ala Glu Leu Leu Leu Leu Arg Gly Gly Ile Arg Glu 
                85                  90                  95      


Gly Ser Leu Asp Leu Gly His Ala Pro Leu Gly Pro Tyr Ala Arg Gly 
            100                 105                 110         


Pro His Tyr Asp Ala Gly Phe Thr Leu Leu Val Pro Met Phe Ser Leu 
        115                 120                 125             


Asp Gly Thr Glu Leu Gln Leu Asp Leu Glu Ser Cys Tyr Ala Gln Val 
    130                 135                 140                 


Cys Leu Pro Glu Met Val Cys Gly Thr Pro Ile Arg Glu Met Trp Gln 
145                 150                 155                 160 


Asp Cys Leu Gly Pro Pro Val Pro Gly Ala Arg Asp Ser Ile His Arg 
                165                 170                 175     


Thr Glu Ser Glu Glu Ser Ser Lys Asp Trp Gln Ser Ser Val Asp Gln 
            180                 185                 190         


Pro His Ser Tyr Val Thr Glu His Glu Ala Pro Val Ser Leu Glu Lys 
        195                 200                 205             


Ser Pro Ser Asp Val Ser Ala Ser Glu Ser Pro Gln His Asp Val Val 
    210                 215                 220                 


Asp Leu Gly Ser Thr Ala Pro Leu Lys Thr Met Ser Ser Asp Val Thr 
225                 230                 235                 240 


Lys Ala Ala Val Glu Ser Pro Val Pro Lys Pro Ser Glu Ala Arg Glu 
                245                 250                 255     


Ala Trp Pro Thr 
            260 


<210>  2668
<211>  75
<212>  PRT
<213>  Homo Sapiens

<400>  2668

Thr Met Phe Ile Ser Thr Glu Gln Thr Glu Arg Asp Ser Ala Thr Ala 
1               5                   10                  15      


Tyr Arg Met Thr Val Glu Val Leu Gly Thr Val Leu Gly Thr Ala Ile 
            20                  25                  30          


Gln Gly Gln Ile Val Gly Gln Ala Asp Thr Pro Cys Phe Gln Asp Leu 
        35                  40                  45              


Asn Ser Ser Thr Val Ala Ser Gln Ser Ala Asn His Thr His Gly Thr 
    50                  55                  60                  


Thr Ser His Arg Glu Thr Gln Lys Ala Tyr Leu 
65                  70                  75  


<210>  2669
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  2669

Ile Glu Phe Thr Gly Leu Arg Ser Asn Leu Ser Gly Pro Gln Gln Ile 
1               5                   10                  15      


Ser Leu Phe Asp Leu Pro Ser Glu Trp Tyr Leu Lys Thr Arg Gln Ser 
            20                  25                  30          


Val Gln Gln Phe Thr Val Cys Gln Ile Gly Leu Ser Val Phe Ser Ala 
        35                  40                  45              


Ile Glu Gly Glu Ala Asn Lys Tyr Ile Ala His Ser Cys Asn Phe Tyr 
    50                  55                  60                  


Leu Phe Pro Thr Thr Phe Gly Ile Leu Asp Ser Glu Phe Ser Phe Gln 
65                  70                  75                  80  


Ala Ser Ser Val Gln Phe Leu Asn Gln Tyr Gly Phe Asn Tyr Asn Lys 
                85                  90                  95      


Phe Leu Lys Asn Gly Ile Pro Tyr Met Asn Glu Glu Gln Glu Lys Lys 
            100                 105                 110         


Ile Arg His Asp Ile Leu Thr Gly Asn Trp Arg Val Arg Ser Ser Pro 
        115                 120                 125             


Asp Lys Asp Gln Ile Lys Val Val Ile Asp Glu Val Thr Arg Trp Leu 
    130                 135                 140                 


Glu Leu Ala Lys Glu Gly Asp Trp Met Thr Leu Pro Gly Ile Thr Gly 
145                 150                 155                 160 


Phe Gln Ala Phe Glu Val Gln Leu Val Leu Arg Gln Ala Leu Pro Asn 
                165                 170                 175     


Ile Trp Thr Val Leu Lys Asp Glu Gly Val Val Val Lys Lys Val Ser 
            180                 185                 190         


Lys Gln His Arg Trp Tyr Leu Gln Asn Thr Ser Cys Asp Arg Glu Ser 
        195                 200                 205             


Cys Trp Lys Glu Asn Ile Leu Leu Ser Ala Arg Gly Phe Ser Val Phe 
    210                 215                 220                 


Phe Gln Met Leu Val Lys Ala Gln Lys Pro Leu Val Gly His Asn Met 
225                 230                 235                 240 


Met Met Asp Leu Leu His Leu His Glu Lys Phe Phe Arg Pro Leu Pro 
                245                 250                 255     


Glu Ser Tyr Asp Gln Phe Lys Gln Asn Ile His Ser Leu Phe Pro Val 
            260                 265                 270         


Leu Ile Asp Thr Lys Ser Val Thr Lys Asp Ile Trp Lys Glu Met Asn 
        275                 280                 285             


Phe Pro Arg Val Ser Asn Leu Ser Glu Val Tyr Glu Val Leu Asn Ser 
    290                 295                 300                 


Asp Leu Asn Pro Thr Lys Asn Ser Gly Pro Glu Ile Val His Ala Ser 
305                 310                 315                 320 


Arg Cys Glu Lys Tyr Val Glu Thr Lys Cys Pro His Glu Ala Ala Tyr 
                325                 330                 335     


Asp Ala Phe Leu Cys Gly Ser Val Leu Leu Lys Val Ala His Leu Leu 
            340                 345                 350         


Leu Gln Lys Ile Tyr His Ile Asp Pro Val Pro Glu Ser Ser Phe Pro 
        355                 360                 365             


Gln Tyr Leu Asp Val Leu Ala Pro Tyr Val Asn Gln Val Asn Leu Ile 
    370                 375                 380                 


Arg Ala Gly Val Pro Lys Ile Asn Phe Ser Gly Pro Asp Tyr Pro Ser 
385                 390                 395                 400 


Ile Arg Pro Pro Ile Leu Ile Leu Ser Val Lys Arg Trp Pro Gly Val 
                405                 410                 415     


Ser Glu Gln Gln Val Tyr His Lys Phe Gln Asn Leu Cys Lys Phe Asp 
            420                 425                 430         


Val Arg Arg Leu Thr Arg Ser Gln Phe Leu Leu Leu Thr Asn Lys Phe 
        435                 440                 445             


Lys Asp Ala Arg Asn Ile Leu Lys Glu Tyr Arg Asp His Pro Thr Leu 
    450                 455                 460                 


Cys Ile Ser Leu Tyr Arg Tyr Trp Arg His Ser Pro Asn 
465                 470                 475         


<210>  2670
<211>  182
<212>  PRT
<213>  Homo Sapiens

<400>  2670

Phe Asn Leu Gln Val Ala Thr Pro Gly Gly Lys Ala Met Glu Phe Val 
1               5                   10                  15      


Asp Val Thr Glu Ser Asn Ala Arg Trp Val Gln Asp Phe Arg Leu Lys 
            20                  25                  30          


Ala Tyr Ala Ser Pro Ala Lys Leu Glu Ser Ile Asp Gly Ala Arg Tyr 
        35                  40                  45              


His Ala Leu Leu Ile Pro Ser Cys Pro Gly Ala Leu Thr Asp Leu Ala 
    50                  55                  60                  


Ser Ser Gly Ser Leu Ala Arg Ile Leu Gln His Phe His Ser Glu Ser 
65                  70                  75                  80  


Lys Pro Ile Cys Ala Val Gly His Gly Val Ala Ala Leu Cys Cys Ala 
                85                  90                  95      


Thr Asn Glu Asp Arg Ser Trp Val Phe Asp Ser Tyr Ser Leu Thr Gly 
            100                 105                 110         


Pro Ser Val Cys Glu Leu Val Arg Ala Pro Gly Phe Ala Arg Leu Pro 
        115                 120                 125             


Leu Val Val Glu Asp Phe Val Lys Asp Ser Gly Ala Cys Phe Ser Ala 
    130                 135                 140                 


Ser Glu Pro Asp Ala Val His Val Val Leu Asp Arg His Leu Val Thr 
145                 150                 155                 160 


Gly Gln Asn Ala Ser Ser Thr Val Pro Ala Val Gln Asn Leu Leu Phe 
                165                 170                 175     


Leu Cys Gly Ser Arg Lys 
            180         


<210>  2671
<211>  278
<212>  PRT
<213>  Homo Sapiens

<400>  2671

His Leu Gly Val Leu Gly Pro Lys Asn Val Ser Gln Lys Asp Ala Glu 
1               5                   10                  15      


Phe Glu Arg Thr Tyr Val Asp Glu Val Asn Ser Glu Leu Val Asn Ile 
            20                  25                  30          


Tyr Thr Phe Asn His Thr Val Thr Arg Asn Arg Thr Glu Gly Val Arg 
        35                  40                  45              


Val Ser Val Asn Val Leu Asn Lys Gln Lys Gly Ala Pro Leu Leu Phe 
    50                  55                  60                  


Val Val Arg Gln Lys Glu Ala Val Val Ser Phe Gln Val Pro Leu Ile 
65                  70                  75                  80  


Leu Arg Gly Met Phe Gln Arg Lys Tyr Leu Tyr Gln Lys Val Glu Arg 
                85                  90                  95      


Thr Leu Cys Gln Pro Pro Thr Lys Asn Glu Ser Glu Ile Gln Phe Phe 
            100                 105                 110         


Tyr Val Asp Val Ser Thr Leu Ser Pro Val Asn Thr Thr Tyr Gln Leu 
        115                 120                 125             


Arg Val Ser Arg Met Asp Asp Phe Val Leu Arg Thr Gly Glu Gln Phe 
    130                 135                 140                 


Ser Phe Asn Thr Thr Ala Ala Gln Pro Gln Tyr Phe Lys Tyr Glu Leu 
145                 150                 155                 160 


Pro Glu Gly Val Asp Ser Val Ile Val Lys Val Thr Ser Asn Lys Ala 
                165                 170                 175     


Phe Pro Cys Ser Val Ile Ser Ile Gln Asp Val Leu Cys Pro Val Tyr 
            180                 185                 190         


Asp Leu Asp Asn Asn Val Ala Phe Ile Gly Met Tyr Gln Thr Met Thr 
        195                 200                 205             


Lys Lys Ala Ala Ile Thr Val Gln Arg Lys Asp Phe Pro Ser Asn Ser 
    210                 215                 220                 


Phe Tyr Val Val Val Val Val Lys Thr Glu Asp Gln Ala Cys Gly Gly 
225                 230                 235                 240 


Ser Leu Pro Phe Tyr Pro Phe Ala Glu Asp Glu Pro Val Asp Gln Gly 
                245                 250                 255     


His Arg Gln Lys Thr Leu Ser Val Leu Val Ser Gln Ala Val Thr Ser 
            260                 265                 270         


Glu Ala Tyr Val Ser Gly 
        275             


<210>  2672
<211>  341
<212>  PRT
<213>  Homo Sapiens

<400>  2672

Ser Gln Glu Ala Gly Thr Gly Ala Gly Ala Gly Ser Leu Ala Gly Ser 
1               5                   10                  15      


Cys Gly Cys Gly Thr Pro Gln Arg Pro Gly Ala His Gly Ser Ser Ala 
            20                  25                  30          


Ala Ala His Arg Tyr Ser Arg Glu Ala Asn Ala Pro Gly Pro Val Pro 
        35                  40                  45              


Gly Glu Arg Gln Leu Ala His Ser Lys Met Val Pro Ile Pro Ala Gly 
    50                  55                  60                  


Val Phe Thr Met Gly Thr Asp Asp Pro Gln Ile Lys Gln Asp Gly Glu 
65                  70                  75                  80  


Ala Pro Ala Arg Arg Val Thr Ile Asp Ala Phe Tyr Met Asp Ala Tyr 
                85                  90                  95      


Glu Val Ser Asn Thr Glu Phe Glu Lys Phe Val Asn Ser Thr Gly Tyr 
            100                 105                 110         


Leu Thr Glu Ala Glu Lys Phe Gly Asp Ser Phe Val Phe Glu Gly Met 
        115                 120                 125             


Leu Ser Glu Gln Val Lys Thr Asn Ile Gln Gln Ala Val Ala Ala Ala 
    130                 135                 140                 


Pro Trp Trp Leu Pro Val Lys Gly Ala Asn Trp Arg His Pro Glu Gly 
145                 150                 155                 160 


Pro Asp Ser Thr Ile Leu His Arg Pro Asp His Pro Val Leu His Val 
                165                 170                 175     


Ser Trp Asn Asp Ala Val Ala Tyr Cys Thr Trp Ala Gly Lys Arg Leu 
            180                 185                 190         


Pro Thr Glu Ala Glu Trp Glu Tyr Ser Cys Arg Gly Gly Leu His Asn 
        195                 200                 205             


Arg Leu Phe Pro Trp Gly Asn Lys Leu Gln Pro Lys Gly Gln His Tyr 
    210                 215                 220                 


Ala Asn Ile Trp Gln Gly Glu Phe Pro Val Thr Asn Thr Gly Glu Asp 
225                 230                 235                 240 


Gly Phe Gln Gly Thr Ala Pro Val Asp Ala Phe Pro Pro Asn Gly Tyr 
                245                 250                 255     


Gly Leu Tyr Asn Ile Val Gly Asn Ala Trp Glu Trp Thr Ser Asp Trp 
            260                 265                 270         


Trp Thr Val His His Ser Val Glu Glu Thr Leu Asn Pro Lys Gly Pro 
        275                 280                 285             


Pro Ser Gly Lys Asp Arg Val Lys Lys Gly Gly Ser Tyr Met Cys His 
    290                 295                 300                 


Arg Ser Tyr Cys Tyr Arg Tyr Arg Cys Ala Ala Arg Ser Gln Asn Thr 
305                 310                 315                 320 


Pro Asp Ser Ser Ala Ser Asn Leu Gly Phe Arg Cys Ala Ala Asp Arg 
                325                 330                 335     


Leu Pro Thr Met Asp 
            340     


<210>  2673
<211>  369
<212>  PRT
<213>  Homo Sapiens

<400>  2673

Arg Gln Lys Glu Ser Gly Ser Lys Trp Lys Val Phe Ile Asp Gln Ile 
1               5                   10                  15      


Asn Arg Ser Leu Glu Asn Tyr Glu Pro Cys Ser Ser Gln Asn Cys Ser 
            20                  25                  30          


Cys Tyr His Gly Val Ile Glu Glu Asp Leu Thr Pro Phe Arg Gly Gly 
        35                  40                  45              


Ile Ser Arg Arg Met Met Ala Glu Val Val Arg Arg Lys Leu Gly Thr 
    50                  55                  60                  


His Tyr Gln Ile Thr Lys Asn Arg Leu Tyr Arg Glu Asn Asp Cys Met 
65                  70                  75                  80  


Phe Pro Ser Arg Cys Ser Gly Val Glu His Phe Ile Leu Glu Val Ile 
                85                  90                  95      


Gly Arg Leu Pro Asp Met Glu Met Val Ile Asn Val Arg Asp Tyr Pro 
            100                 105                 110         


Gln Val Pro Lys Trp Met Glu Pro Ala Ile Pro Val Phe Ser Phe Ser 
        115                 120                 125             


Lys Thr Ser Glu Tyr His Asp Ile Met Tyr Pro Ala Trp Thr Phe Trp 
    130                 135                 140                 


Glu Gly Gly Pro Ala Val Trp Pro Ile Tyr Pro Thr Gly Leu Gly Arg 
145                 150                 155                 160 


Trp Asp Leu Phe Arg Glu Asp Leu Val Arg Ser Ala Ala Gln Trp Pro 
                165                 170                 175     


Trp Lys Lys Lys Asn Ser Thr Ala Tyr Phe Arg Gly Ser Arg Thr Ser 
            180                 185                 190         


Pro Glu Arg Asp Pro Leu Ile Leu Leu Ser Arg Lys Asn Thr Lys Leu 
        195                 200                 205             


Val Asp Ala Glu Tyr Thr Lys Asn Gln Ala Trp Lys Ser Met Lys Asp 
    210                 215                 220                 


Thr Leu Gly Lys Pro Ala Ala Lys Asp Val His Leu Val Asp His Cys 
225                 230                 235                 240 


Lys Tyr Lys Tyr Leu Phe Asn Phe Arg Gly Val Ala Ala Ser Phe Arg 
                245                 250                 255     


Phe Lys His Leu Phe Leu Cys Gly Ser Leu Val Phe His Val Gly Asp 
            260                 265                 270         


Glu Trp Leu Glu Phe Phe Tyr Pro Gln Leu Lys Pro Trp Val His Tyr 
        275                 280                 285             


Ile Pro Val Lys Thr Asp Leu Ser Asn Val Gln Glu Leu Leu Gln Phe 
    290                 295                 300                 


Val Lys Ala Asn Asp Asp Val Ala Gln Glu Ile Ala Glu Arg Gly Ser 
305                 310                 315                 320 


Gln Phe Ile Arg Asn His Leu Gln Met Asp Asp Ile Thr Cys Tyr Trp 
                325                 330                 335     


Glu Asn Leu Leu Ser Glu Tyr Ser Lys Phe Leu Ser Tyr Asn Val Thr 
            340                 345                 350         


Arg Arg Lys Gly Tyr Asp Gln Ile Ile Pro Lys Met Leu Lys Thr Glu 
        355                 360                 365             


Leu 
    


<210>  2674
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  2674

Glu Ser Phe Val Lys Leu Phe Ile Pro Lys Arg Arg Lys Ser Val Thr 
1               5                   10                  15      


Gly Glu Ile Val Leu Ile Thr Gly Ala Gly His Gly Ile Gly Arg Leu 
            20                  25                  30          


Thr Ala Tyr Glu Phe Ala Lys Leu Lys Ser Lys Leu Val Leu Trp Asp 
        35                  40                  45              


Ile Asn Lys His Gly Leu Glu Glu Thr Ala Ala Lys Cys Lys Gly Leu 
    50                  55                  60                  


Gly Ala Lys Val His Thr Phe Val Val Asp Cys Ser Asn Arg Glu Asp 
65                  70                  75                  80  


Ile Tyr Ser Ser Ala Lys Lys Val Lys Ala Glu Ile Gly Asp Val Ser 
                85                  90                  95      


Ile Leu Val Asn Asn Ala Gly Val Val Tyr Thr Ser Asp Leu Phe Ala 
            100                 105                 110         


Thr Gln Asp Pro Gln Ile Glu Lys Thr Phe Glu Val Asn Val Leu Ala 
        115                 120                 125             


His Phe Trp Thr Thr Lys Ala Phe Leu Pro Ala Met Thr Lys Asn Asn 
    130                 135                 140                 


His Gly His Ile Val Thr Val Ala Ser Ala Ala Gly His Val Ser Val 
145                 150                 155                 160 


Pro Phe Leu Leu Ala Tyr Cys Ser Ser Lys Phe Ala Ala Val Gly Phe 
                165                 170                 175     


His Lys Thr Leu Thr Asp Glu Leu Ala Ala Leu Gln Ile Thr Gly Val 
            180                 185                 190         


Lys Thr Thr Cys Leu Cys Pro Asn Phe Val Asn Thr Gly Phe Ile Lys 
        195                 200                 205             


Asn Pro Ser Thr Ser Leu Gly Pro Thr Leu Glu Pro Glu Glu Val Val 
    210                 215                 220                 


Asn Arg Leu Met His Gly Ile Leu Thr Glu Gln Lys Met Ile Phe Ile 
225                 230                 235                 240 


Pro Ser Ser Ile Ala Phe Leu Thr Thr Leu Glu Arg Ile Leu Pro Glu 
                245                 250                 255     


Arg Phe Leu Ala Val Leu Lys Arg Lys Ile Ser Val Lys Phe Asp Ala 
            260                 265                 270         


Val Ile Gly Tyr Lys Met Lys Ala Gln 
        275                 280     


<210>  2675
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  2675

Arg Ala Leu Glu Trp Phe Ser Ala Val Val Asn Ile Glu Tyr Val Asp 
1               5                   10                  15      


Pro Gln Thr Asn Leu Thr Val Trp Ser Val Ser Glu Ser Gly Arg Phe 
            20                  25                  30          


Gly Asp Ser Ser Pro Lys Glu Gly Ala His Gly Leu Val Gly Val Pro 
        35                  40                  45              


Trp Ala Pro Gly Gly Asp Leu Glu Gly Cys Ala Pro Asp Thr Arg Phe 
    50                  55                  60                  


Phe Val Pro Glu Pro Gly Gly Arg Gly Ala Ala Pro Trp Val Ala Leu 
65                  70                  75                  80  


Val Ala Arg Gly Gly Cys Thr Phe Lys Asp Lys Val Leu Val Ala Ala 
                85                  90                  95      


Arg Arg Asn Ala Ser Ala Val Val Leu Tyr Asn Glu Glu Arg Tyr Gly 
            100                 105                 110         


Asn Ile Thr Leu Pro Met Ser His Ala Gly Thr Gly Asn Ile Val Val 
        115                 120                 125             


Ile Met Ile Ser Tyr Pro Lys Gly Arg Glu Ile Leu Glu Leu Val Gln 
    130                 135                 140                 


Lys Gly Ile Pro Val Thr Met Thr Ile Gly Val Gly Thr Arg His Val 
145                 150                 155                 160 


Gln Glu Phe Ile Ser Gly Gln Ser 
                165             


<210>  2676
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  2676

Arg Thr Asp Ser Pro Ser Pro Thr Val Leu Asn Ser His Ile Ser Thr 
1               5                   10                  15      


Pro Asn Val Asn Ala Leu Thr His Glu Asn Gln Thr Lys Pro Ser Ile 
            20                  25                  30          


Ser Gln Ile Ser Thr Thr Leu Pro Pro Thr Thr Ser Thr Lys Lys Ser 
        35                  40                  45              


Gly Gly Ala Ser Val Val Pro His Pro Ser Pro Thr Pro Leu Ser Gln 
    50                  55                  60                  


Glu Glu Ala Asp Asn Asn Glu Asp Pro Ser Ile Glu Glu Glu Asp Leu 
65                  70                  75                  80  


Leu Met Leu Asn Ser Ser Pro Ser Thr Ala Lys Asp Thr Leu Asp Asn 
                85                  90                  95      


Gly Asp Tyr Gly Glu Pro Asp Tyr Asp Trp Thr Thr Gly Pro Arg Asp 
            100                 105                 110         


Asp Asp Glu Ser Asp Asp Thr Leu Glu Glu Asn Arg Gly Tyr Met Glu 
        115                 120                 125             


Ile Glu Gln Ser Val Lys Ser Phe Lys Met Pro Ser Ser Asn Ile Glu 
    130                 135                 140                 


Glu Glu Asp 
145         


<210>  2677
<211>  325
<212>  PRT
<213>  Homo Sapiens

<400>  2677

Ile Ala Val Ala Gln Lys Thr Gln Asp Gly Gln Asn Ile Gly Ile Lys 
1               5                   10                  15      


His Ile Pro Ala Thr Gln Cys Gly Ile Trp Val Arg Thr Ser Asn Gly 
            20                  25                  30          


Gly His Phe Ala Ser Pro Asn Tyr Pro Asp Ser Tyr Pro Pro Asn Lys 
        35                  40                  45              


Glu Cys Ile Tyr Ile Leu Glu Ala Ala Pro Arg Gln Arg Ile Glu Leu 
    50                  55                  60                  


Thr Phe Asp Glu His Tyr Tyr Ile Glu Pro Ser Phe Glu Cys Arg Phe 
65                  70                  75                  80  


Asp His Leu Glu Val Arg Asp Gly Pro Phe Gly Phe Ser Pro Leu Ile 
                85                  90                  95      


Asp Arg Tyr Cys Gly Val Lys Ser Pro Pro Leu Ile Arg Ser Thr Gly 
            100                 105                 110         


Arg Phe Met Trp Ile Lys Phe Ser Ser Asp Glu Glu Leu Glu Gly Leu 
        115                 120                 125             


Gly Phe Arg Ala Lys Tyr Ser Phe Ile Pro Asp Pro Asp Phe Thr Tyr 
    130                 135                 140                 


Leu Gly Gly Ile Leu Asn Pro Ile Pro Asp Cys Gln Phe Glu Leu Ser 
145                 150                 155                 160 


Gly Ala Asp Gly Ile Val Arg Ser Ser Gln Val Glu Gln Glu Glu Lys 
                165                 170                 175     


Thr Lys Pro Gly Gln Ala Val Asp Cys Ile Trp Thr Ile Lys Ala Thr 
            180                 185                 190         


Pro Lys Ala Lys Ile Tyr Leu Arg Phe Leu Asp Tyr Gln Met Glu His 
        195                 200                 205             


Ser Asn Glu Cys Lys Arg Asn Phe Val Ala Val Tyr Asp Gly Ser Ser 
    210                 215                 220                 


Ser Ile Glu Asn Leu Lys Ala Lys Phe Cys Ser Thr Val Ala Asn Asp 
225                 230                 235                 240 


Val Met Leu Lys Thr Gly Ile Gly Val Ile Arg Met Trp Ala Asp Glu 
                245                 250                 255     


Gly Ser Arg Leu Ser Arg Phe Arg Met Leu Phe Thr Ser Phe Val Glu 
            260                 265                 270         


Pro Pro Cys Thr Ser Ser Thr Phe Phe Cys His Ser Asn Met Cys Ile 
        275                 280                 285             


Asn Asn Ser Leu Val Cys Asn Gly Val Gln Asn Cys Ala Tyr Pro Trp 
    290                 295                 300                 


Asp Glu Asn His Cys Lys Glu Lys Lys Lys Ala Gly Val Phe Glu Gln 
305                 310                 315                 320 


Ile Thr Lys Thr His 
                325 


<210>  2678
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2678

Trp Val His Gly Asp Pro Arg Arg Ala Ala Tyr Pro Thr Asp Ser Gln 
1               5                   10                  15      


Gly His Phe Cys Gly Gln Lys Gly Thr Pro Asn Glu Asn Lys Thr Ile 
            20                  25                  30          


Leu Phe Tyr Phe Asn Leu Leu Arg Cys Thr Ser Pro Ser Val Leu Leu 
        35                  40                  45              


Asn Leu Gln Cys Pro Thr Thr Gln Ile Cys Val Ser Lys Cys Pro Glu 
    50                  55                  60                  


Lys Phe Leu Thr Tyr Val Glu Met Gln Leu Leu Tyr Thr Lys Asp Lys 
65                  70                  75                  80  


Ser Tyr Trp Glu Asp Tyr Arg Gln Phe Cys Lys Thr Thr Ala Lys Pro 
                85                  90                  95      


Val Lys Ser Leu Thr Gln Leu Leu Leu Asp Asp Asp Cys Pro Thr Ala 
            100                 105                 110         


Ile Phe Pro Ser Lys Pro Phe Leu Gln Arg Cys Phe Pro Asp Phe Ser 
        115                 120                 125             


Thr Lys Asn Gly Thr Leu Thr Ile Gly Ser Lys Met Met Phe Gln Asp 
    130                 135                 140                 


Gly Asn Gly Gly Thr Arg Ser Val Val Glu Leu Gly Ile Ala Ala Asn 
145                 150                 155                 160 


Gly Ile Asn Lys Leu Leu Asp Ala Lys Ser Leu Gly Leu Lys Val Phe 
                165                 170                 175     


Glu Asp Tyr Ala Arg Thr Trp 
            180             


<210>  2679
<211>  241
<212>  PRT
<213>  Homo Sapiens

<400>  2679

Asp Ser Glu Val Met Ala Ser Thr Val Val Lys Tyr Leu Ser Gln Glu 
1               5                   10                  15      


Glu Ala Gln Ala Val Asp Gln Glu Leu Phe Asn Glu Tyr Gln Phe Ser 
            20                  25                  30          


Val Asp Gln Leu Met Glu Leu Ala Gly Leu Ser Cys Ala Thr Ala Ile 
        35                  40                  45              


Ala Lys Ala Tyr Pro Pro Thr Ser Met Ser Arg Ser Pro Pro Thr Val 
    50                  55                  60                  


Leu Val Ile Cys Gly Pro Gly Asn Asn Gly Gly Asp Gly Leu Val Cys 
65                  70                  75                  80  


Ala Arg His Leu Lys Leu Phe Gly Tyr Glu Pro Thr Ile Tyr Tyr Pro 
                85                  90                  95      


Lys Arg Pro Asn Lys Pro Leu Phe Thr Ala Leu Val Thr Gln Cys Gln 
            100                 105                 110         


Lys Met Asp Ile Pro Phe Leu Gly Glu Met Pro Ala Glu Pro Met Thr 
        115                 120                 125             


Ile Asp Glu Leu Tyr Glu Leu Val Val Asp Ala Ile Phe Gly Phe Ser 
    130                 135                 140                 


Phe Lys Gly Asp Val Arg Glu Pro Phe His Ser Ile Leu Ser Val Leu 
145                 150                 155                 160 


Lys Gly Leu Thr Val Pro Ile Ala Ser Ile Asp Ile Pro Ser Gly Trp 
                165                 170                 175     


Asp Val Glu Lys Gly Asn Ala Gly Gly Ile Gln Pro Asp Leu Leu Ile 
            180                 185                 190         


Ser Leu Thr Ala Pro Lys Lys Ser Ala Thr Gln Phe Thr Gly Arg Tyr 
        195                 200                 205             


His Tyr Leu Gly Gly Arg Phe Val Pro Pro Ala Leu Glu Lys Lys Tyr 
    210                 215                 220                 


Gln Leu Asn Leu Pro Pro Tyr Pro Asp Thr Glu Cys Val Tyr Arg Leu 
225                 230                 235                 240 


Gln 
    


<210>  2680
<211>  395
<212>  PRT
<213>  Homo Sapiens

<400>  2680

Leu Ala Ser Trp Gln Arg Asn Glu Leu Thr Asp Arg Arg Phe Leu Gln 
1               5                   10                  15      


Leu Asn Lys Cys Pro Ala Cys Phe Gly Thr Ser Trp Cys Arg Arg Phe 
            20                  25                  30          


Leu Asn Gly Gln Val Val Phe Glu Ala Trp Gly Arg Leu Arg Leu Leu 
        35                  40                  45              


Asp Phe Leu Asn Val Lys Asn Val Tyr Phe Ala Gln Tyr Gly Glu Pro 
    50                  55                  60                  


Arg Glu Gly Gly Arg Arg Arg Val Val Leu Lys Arg Leu Gly Ser Gln 
65                  70                  75                  80  


Arg Glu Leu Ala Gln Leu Asp Gln Ser Ile Cys Lys Arg Ala Thr Gly 
                85                  90                  95      


Arg Pro Arg Cys Asp Leu Leu Gln Ala Met Pro Arg Thr Glu Phe Ala 
            100                 105                 110         


Arg Leu Asn Gly Asp Val Arg Leu Leu Thr Pro Glu Ala Val Glu Gly 
        115                 120                 125             


Trp Ser Asp Leu Val His Cys Pro Ser Gln Arg Leu Leu Asp Arg Leu 
    130                 135                 140                 


Val Arg Arg Tyr Ala Glu Thr Lys Asp Ser Gly Ser Phe Leu Leu Arg 
145                 150                 155                 160 


Asn Leu Lys Asp Ser Glu Arg Met Gln Leu Leu Leu Thr Leu Ala Phe 
                165                 170                 175     


Asn Pro Glu Pro Leu Val Leu Gln Ser Phe Pro Ser Asp Glu Gly Trp 
            180                 185                 190         


Pro Phe Ala Lys Tyr Leu Gly Ala Cys Gly Arg Met Val Ala Val Asn 
        195                 200                 205             


Tyr Val Gly Glu Glu Leu Trp Ser Tyr Phe Asn Ala Pro Trp Glu Lys 
    210                 215                 220                 


Arg Val Asp Leu Ala Trp Gln Leu Met Glu Ile Ala Glu Gln Leu Thr 
225                 230                 235                 240 


Asn Asn Asp Phe Glu Phe Ala Leu Tyr Leu Leu Asp Val Ser Phe Asp 
                245                 250                 255     


Asn Phe Ala Val Gly Pro Arg Asp Gly Lys Val Ile Ile Val Asp Ala 
            260                 265                 270         


Glu Asn Val Leu Val Ala Asp Lys Arg Leu Ile Arg Gln Asn Lys Pro 
        275                 280                 285             


Glu Asn Trp Asp Val Trp Tyr Glu Ser Lys Phe Asp Asp Cys Asp Lys 
    290                 295                 300                 


Glu Ala Cys Leu Ser Phe Ser Lys Glu Ile Leu Cys Ala Arg Ala Thr 
305                 310                 315                 320 


Val Asp His Asn Tyr Tyr Ala Val Cys Gln Asn Leu Leu Ser Arg His 
                325                 330                 335     


Ala Thr Trp Arg Gly Thr Ser Gly Gly Leu Leu His Asp Pro Pro Ser 
            340                 345                 350         


Glu Ile Ala Lys Asp Gly Arg Leu Glu Ala Leu Leu Asp Glu Cys Ala 
        355                 360                 365             


Asn Pro Lys Lys Arg Tyr Gly Arg Phe Gln Ala Ala Lys Glu Leu Arg 
    370                 375                 380                 


Glu Tyr Leu Ala Gln Leu Ser Asn Asn Val Arg 
385                 390                 395 


<210>  2681
<211>  48
<212>  PRT
<213>  Homo Sapiens

<400>  2681

Met Asn Tyr Thr Glu Ser Ser Pro Leu Arg Glu Ser Thr Ala Ile Gly 
1               5                   10                  15      


Phe Thr Pro Glu Leu Glu Ser Ile Ile Pro Val Pro Ser Asn Lys Thr 
            20                  25                  30          


Thr Cys Glu Asn Trp Arg Glu Ile His His Leu Val Phe His Val Ala 
        35                  40                  45              


<210>  2682
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  2682

Leu His Pro Thr Gly Asn Ile Thr Gly Leu Pro Gly Ser Lys Arg Ser 
1               5                   10                  15      


Gln Pro Pro Arg Asn Ile Thr Lys Glu Pro Lys Val Phe Phe His Lys 
            20                  25                  30          


Thr Gln Leu Pro Gly Ile Gln Gly Ala Ala Ser Arg Ser Thr Ala Ala 
        35                  40                  45              


Ser Pro Thr Asn Pro Met Lys Phe Leu Arg Asn Lys Ala Ile Ile Arg 
    50                  55                  60                  


His Arg Pro Ala Leu Val Lys 
65                  70      


<210>  2683
<211>  518
<212>  PRT
<213>  Homo Sapiens

<400>  2683

Gln Asp Ser Thr Gln Ala Ser Thr Pro Gly Ser Pro Leu Ser Pro Thr 
1               5                   10                  15      


Glu Tyr Glu Arg Phe Phe Ala Leu Leu Thr Pro Thr Trp Lys Ala Glu 
            20                  25                  30          


Thr Thr Cys Arg Leu Arg Ala Thr His Gly Cys Arg Asn Pro Thr Leu 
        35                  40                  45              


Val Gln Leu Asp Gln Tyr Glu Asn His Gly Leu Val Pro Asp Gly Ala 
    50                  55                  60                  


Val Cys Ser Asn Leu Pro Tyr Ala Ser Trp Phe Glu Ser Phe Cys Gln 
65                  70                  75                  80  


Phe Thr His Tyr Arg Cys Ser Asn His Val Tyr Tyr Ala Lys Arg Val 
                85                  90                  95      


Leu Cys Ser Gln Pro Val Ser Ile Leu Ser Pro Asn Thr Leu Lys Glu 
            100                 105                 110         


Ile Glu Ala Ser Ala Glu Val Ser Pro Thr Thr Met Thr Ser Pro Ile 
        115                 120                 125             


Ser Pro His Phe Thr Val Thr Glu Arg Gln Thr Phe Gln Pro Trp Pro 
    130                 135                 140                 


Glu Arg Leu Ser Asn Asn Val Glu Glu Leu Leu Gln Ser Ser Leu Ser 
145                 150                 155                 160 


Leu Gly Gly Gln Glu Gln Ala Pro Glu His Lys Gln Glu Gln Gly Val 
                165                 170                 175     


Glu His Arg Gln Glu Pro Thr Gln Glu His Lys Gln Glu Glu Gly Gln 
            180                 185                 190         


Lys Gln Glu Glu Gln Glu Glu Glu Gln Glu Glu Glu Gly Lys Gln Glu 
        195                 200                 205             


Glu Gly Gln Gly Thr Lys Glu Gly Arg Glu Ala Val Ser Gln Leu Gln 
    210                 215                 220                 


Thr Asp Ser Glu Pro Lys Phe His Ser Glu Ser Leu Ser Ser Asn Pro 
225                 230                 235                 240 


Ser Ser Phe Ala Pro Arg Val Arg Glu Val Glu Ser Thr Pro Met Ile 
                245                 250                 255     


Met Glu Asn Ile Gln Glu Leu Ile Arg Ser Ala Gln Glu Ile Asp Glu 
            260                 265                 270         


Met Asn Glu Ile Tyr Asp Glu Asn Ser Tyr Trp Arg Asn Gln Asn Pro 
        275                 280                 285             


Gly Ser Leu Leu Gln Leu Pro His Thr Glu Ala Leu Leu Val Leu Cys 
    290                 295                 300                 


Tyr Ser Ile Val Glu Asn Thr Cys Ile Ile Thr Pro Thr Ala Lys Ala 
305                 310                 315                 320 


Trp Lys Tyr Met Glu Glu Glu Ile Leu Gly Phe Gly Lys Ser Val Cys 
                325                 330                 335     


Asp Ser Leu Gly Arg Arg His Met Ser Thr Cys Ala Leu Cys Asp Phe 
            340                 345                 350         


Cys Ser Leu Lys Leu Glu Gln Cys His Ser Glu Ala Ser Leu Gln Arg 
        355                 360                 365             


Gln Gln Cys Asp Thr Ser His Lys Thr Pro Phe Val Ser Pro Leu Leu 
    370                 375                 380                 


Ala Ser Gln Ser Leu Ser Ile Gly Asn Gln Val Gly Ser Pro Glu Ser 
385                 390                 395                 400 


Gly Arg Phe Tyr Gly Leu Asp Leu Tyr Gly Gly Leu His Met Asp Phe 
                405                 410                 415     


Trp Cys Ala Arg Leu Ala Thr Lys Gly Cys Glu Asp Val Arg Val Ser 
            420                 425                 430         


Gly Trp Leu Gln Thr Glu Phe Leu Ser Phe Gln Asp Gly Asp Phe Pro 
        435                 440                 445             


Thr Lys Ile Cys Asp Thr Asp Tyr Ile Gln Tyr Pro Asn Tyr Cys Ser 
    450                 455                 460                 


Phe Lys Ser Gln Gln Cys Leu Met Arg Asn Arg Asn Arg Lys Val Ser 
465                 470                 475                 480 


Arg Met Arg Cys Leu Gln Asn Glu Thr Tyr Ser Ala Leu Ser Pro Gly 
                485                 490                 495     


Lys Ser Glu Asp Val Val Leu Arg Trp Ser Gln Glu Phe Ser Thr Leu 
            500                 505                 510         


Thr Leu Gly Gln Phe Gly 
        515             


<210>  2684
<211>  59
<212>  PRT
<213>  Homo Sapiens

<400>  2684

Glu Asp Gly Lys Asn Asp Ser Leu Pro Ser Glu Ser Thr Ser His Arg 
1               5                   10                  15      


Trp Arg Gly Pro Ala Cys Arg Pro Pro Asp Ser Ser Tyr Asn Ser Leu 
            20                  25                  30          


Tyr Ser Thr Cys Leu Glu Leu Phe Lys Phe Thr Ile Gly Met Gly Asp 
        35                  40                  45              


Leu Glu Phe Thr Glu Asn Tyr Asp Phe Lys Ala 
    50                  55                  


<210>  2685
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  2685

Leu Ser Pro Gly Leu Lys Cys Val Cys Leu Leu Cys Asp Ser Ser Asn 
1               5                   10                  15      


Phe Thr Cys Gln Thr Glu Gly Ala Cys Trp Ala Ser Val Met Leu Thr 
            20                  25                  30          


Asn Gly Lys Glu Gln Val Ile Lys Ser Cys Val Ser Leu Pro Glu Leu 
        35                  40                  45              


Asn Ala Gln Val Phe Cys His Ser Ser Asn Asn Val Thr Lys Thr Glu 
    50                  55                  60                  


Cys Cys Phe Thr Asp Phe Cys Asn Asn Ile Thr Leu His Leu Pro Thr 
65                  70                  75                  80  


Ala Ser Pro Asn Ala Pro Lys Leu Gly Pro Met Glu 
                85                  90          


<210>  2686
<211>  51
<212>  PRT
<213>  Homo Sapiens

<400>  2686

Lys Phe Lys Glu Ile Cys Glu Arg Pro Asn Gly Ser Cys Arg Asp Phe 
1               5                   10                  15      


Cys Leu Glu Thr Glu Ile His Val Gly Arg Cys Leu Asn Ser Gln Pro 
            20                  25                  30          


Cys Cys Leu Pro Leu Gly His Gln Pro Arg Ile Glu Ser Thr Thr Pro 
        35                  40                  45              


Lys Lys Asp 
    50      


<210>  2687
<211>  66
<212>  PRT
<213>  Homo Sapiens

<400>  2687

Ser Phe Trp Asn Lys Asp Pro Phe Leu Asp Met Ile Arg Glu Thr Glu 
1               5                   10                  15      


Gln Cys Trp Val Gln Pro Pro Tyr Lys Tyr Cys Glu Lys Arg Cys Thr 
            20                  25                  30          


Lys Ile Met Thr Cys Val Arg Pro Asn His Thr Cys Cys Trp Thr Tyr 
        35                  40                  45              


Cys Gly Asn Ile Cys Leu Asp Asn Glu Glu Pro Leu Lys Ser Met Leu 
    50                  55                  60                  


Asn Pro 
65      


<210>  2688
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  2688

Glu Met Arg Lys Lys Arg Tyr Asp Arg Lys Glu Leu Leu Leu Glu Glu 
1               5                   10                  15      


Cys Trp Gly Lys Pro Asn Val Lys Glu Cys Thr Asn Lys Cys Ser Lys 
            20                  25                  30          


Ala Phe Arg Cys Lys Asp Lys Asn Tyr Thr Cys Cys Trp Thr Tyr Cys 
        35                  40                  45              


Gly Asn Ile Cys Trp Ile Asn Val Glu Thr Ser Gly Asp Tyr 
    50                  55                  60          


<210>  2689
<211>  258
<212>  PRT
<213>  Homo Sapiens

<400>  2689

Arg Lys Ser Ala Ala Cys Gly Gln Pro Arg Met Ser Ser Arg Ile Val 
1               5                   10                  15      


Gly Gly Arg Asp Gly Arg Asp Gly Glu Trp Pro Trp Gln Ala Ser Ile 
            20                  25                  30          


Gln His Arg Gly Ala His Val Cys Gly Gly Ser Leu Ile Ala Pro Gln 
        35                  40                  45              


Trp Val Leu Thr Ala Ala His Cys Phe Pro Arg Arg Ala Leu Pro Ala 
    50                  55                  60                  


Glu Tyr Arg Val Arg Leu Gly Ala Leu Arg Leu Gly Ser Thr Ser Pro 
65                  70                  75                  80  


Arg Thr Leu Ser Val Pro Val Arg Arg Val Leu Leu Pro Pro Asp Tyr 
                85                  90                  95      


Ser Glu Asp Gly Ala Arg Gly Asp Leu Ala Leu Leu Gln Leu Arg Arg 
            100                 105                 110         


Pro Val Pro Leu Ser Ala Arg Val Gln Pro Val Cys Leu Pro Val Pro 
        115                 120                 125             


Gly Ala Arg Pro Pro Pro Gly Thr Pro Cys Arg Val Thr Gly Trp Gly 
    130                 135                 140                 


Ser Leu Arg Pro Gly Val Pro Leu Pro Glu Trp Arg Pro Leu Gln Gly 
145                 150                 155                 160 


Val Arg Val Pro Leu Leu Asp Ser Arg Thr Cys Asp Gly Leu Tyr His 
                165                 170                 175     


Val Gly Ala Asp Val Pro Gln Ala Glu Arg Ile Val Leu Pro Gly Ser 
            180                 185                 190         


Leu Cys Ala Gly Tyr Pro Gln Gly His Lys Asp Ala Cys Gln Gly Asp 
        195                 200                 205             


Ser Gly Gly Pro Leu Thr Cys Leu Gln Ser Gly Ser Trp Val Leu Val 
    210                 215                 220                 


Gly Val Val Ser Trp Gly Lys Gly Cys Ala Leu Pro Asn Arg Pro Gly 
225                 230                 235                 240 


Val Tyr Thr Ser Val Ala Thr Tyr Ser Pro Trp Ile Gln Ala Arg Val 
                245                 250                 255     


Ser Phe 
        


<210>  2690
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  2690

Met Ala Ala Gln Asn Gly Asn Thr Ser Phe Thr Pro Asn Phe Asn Pro 
1               5                   10                  15      


Pro Gln Asp His Ala Ser Ser Leu Ser Phe Asn Phe Ser Tyr Gly Asp 
            20                  25                  30          


Tyr Asp Leu Pro Met Asp Glu Asp Glu Asp Met Thr Lys Thr Arg Thr 
        35                  40                  45              


Phe Phe Ala Ala Lys Ile 
    50                  


<210>  2691
<211>  435
<212>  PRT
<213>  Homo Sapiens

<400>  2691

Asp Pro Gly Ala Leu Leu Arg Leu Gly Met Asp Ile Met Asn Gln Val 
1               5                   10                  15      


Gln Ser Ala Met Asp Glu Ser His Ile Leu Glu Lys Met Ala Ala Glu 
            20                  25                  30          


Ala Gly Lys Lys Gln Pro Gly Met Lys Pro Ile Lys Gly Ile Thr Asn 
        35                  40                  45              


Leu Lys Val Lys Asp Val Gln Leu Pro Val Ile Thr Leu Asn Phe Val 
    50                  55                  60                  


Pro Gly Val Gly Ile Phe Gln Cys Val Ser Thr Gly Met Thr Val Thr 
65                  70                  75                  80  


Gly Lys Ser Phe Met Gly Gly Asn Met Glu Ile Ile Val Ala Leu Asn 
                85                  90                  95      


Ile Thr Ala Thr Asn Arg Leu Leu Arg Asp Glu Glu Thr Gly Leu Pro 
            100                 105                 110         


Val Phe Lys Ser Glu Gly Cys Glu Val Ile Leu Val Asn Val Lys Thr 
        115                 120                 125             


Asn Leu Pro Ser Asn Met Leu Pro Lys Met Val Asn Lys Phe Leu Asp 
    130                 135                 140                 


Ser Thr Leu His Lys Val Leu Pro Gly Leu Met Cys Pro Ala Ile Asp 
145                 150                 155                 160 


Ala Val Leu Val Tyr Val Asn Arg Lys Trp Thr Asn Leu Ser Asp Pro 
                165                 170                 175     


Met Pro Val Gly Gln Met Gly Thr Val Lys Tyr Val Leu Met Ser Ala 
            180                 185                 190         


Pro Ala Thr Thr Ala Ser Tyr Ile Gln Leu Asp Phe Ser Pro Val Val 
        195                 200                 205             


Gln Gln Gln Lys Gly Lys Thr Ile Lys Leu Ala Asp Ala Gly Glu Ala 
    210                 215                 220                 


Leu Thr Phe Pro Glu Gly Tyr Ala Lys Gly Ser Ser Gln Leu Leu Leu 
225                 230                 235                 240 


Pro Ala Thr Phe Leu Ser Ala Glu Leu Ala Leu Leu Gln Lys Ser Phe 
                245                 250                 255     


His Val Asn Ile Gln Asp Thr Met Ile Gly Glu Leu Pro Pro Gln Thr 
            260                 265                 270         


Thr Lys Thr Leu Ala Arg Phe Ile Pro Glu Val Ala Val Ala Tyr Pro 
        275                 280                 285             


Lys Ser Lys Pro Leu Thr Thr Gln Ile Lys Ile Lys Lys Pro Pro Lys 
    290                 295                 300                 


Val Thr Met Lys Thr Gly Lys Ser Leu Leu His Leu His Ser Thr Leu 
305                 310                 315                 320 


Glu Met Phe Ala Ala Arg Trp Arg Ser Lys Ala Pro Met Ser Leu Phe 
                325                 330                 335     


Leu Leu Glu Val His Phe Asn Leu Lys Val Gln Tyr Ser Val His Glu 
            340                 345                 350         


Asn Gln Leu Gln Met Ala Thr Ser Leu Asp Arg Leu Leu Ser Leu Ser 
        355                 360                 365             


Arg Lys Ser Ser Ser Ile Gly Asn Phe Asn Glu Arg Glu Leu Thr Gly 
    370                 375                 380                 


Phe Ile Thr Ser Tyr Leu Glu Glu Ala Tyr Ile Pro Val Val Asn Asp 
385                 390                 395                 400 


Val Leu Gln Val Gly Leu Pro Leu Pro Asp Phe Leu Ala Met Asn Tyr 
                405                 410                 415     


Asn Leu Ala Glu Leu Asp Ile Val Glu Asn Ala Leu Met Leu Asp Leu 
            420                 425                 430         


Lys Leu Gly 
        435 


<210>  2692
<211>  68
<212>  PRT
<213>  Homo Sapiens

<400>  2692

Phe Pro Val Ser Gln Asp Gln Glu Arg Glu Lys Arg Ser Ile Ser Asp 
1               5                   10                  15      


Ser Asp Glu Leu Ala Ser Gly Phe Phe Val Phe Pro Tyr Pro Tyr Pro 
            20                  25                  30          


Phe Arg Pro Leu Pro Pro Ile Pro Phe Pro Arg Phe Pro Trp Phe Arg 
        35                  40                  45              


Arg Asn Phe Pro Ile Pro Ile Pro Glu Ser Ala Pro Thr Thr Pro Leu 
    50                  55                  60                  


Pro Ser Glu Lys 
65              


<210>  2693
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  2693

Tyr Phe Arg Gly Tyr Lys Pro Arg Ser Thr Asp Leu Ile Leu Arg His 
1               5                   10                  15      


Leu Thr Val Ala Asp Ser Leu Val Ile Leu Ser Lys Arg Ile Pro Glu 
            20                  25                  30          


Thr Met Ala Thr Phe Gly Leu Lys His Phe Asp Asn Tyr Phe Gly Cys 
        35                  40                  45              


Lys Phe Leu Leu Tyr Ala His Arg 
    50                  55      


<210>  2694
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  2694

Glu Glu Pro Ala Ala Ser Phe Ser Gln Pro Gly Ser Met Gly Leu Asp 
1               5                   10                  15      


Lys Asn Thr Val His Asp Gln Glu His Ile Met Glu His Leu Glu Gly 
            20                  25                  30          


Val Ile Asn Lys Pro Glu Ala Glu Met Ser Pro Gln Glu Leu Gln Leu 
        35                  40                  45              


His Tyr Phe Lys Met His Asp Tyr Asp Gly Asn Asn Leu Leu Asp Gly 
    50                  55                  60                  


Leu Glu Leu Ser Thr Ala Ile Thr His Val His Lys Glu Glu Gly Ser 
65                  70                  75                  80  


Glu Gln Ala Pro Leu Met Ser Glu Asp Glu Leu Ile Asn Ile Ile Asp 
                85                  90                  95      


Gly Val Leu Arg Asp Asp Asp Lys Asn Asn Asp Gly Tyr Ile Asp Tyr 
            100                 105                 110         


Ala Glu Phe Ala Lys Ser Leu Gln 
        115                 120 


<210>  2695
<211>  183
<212>  PRT
<213>  Homo Sapiens

<400>  2695

Glu Ala Ser Glu Ser Thr Met Lys Ile Ile Lys Glu Glu Phe Thr Asp 
1               5                   10                  15      


Glu Glu Met Gln Tyr Asp Met Ala Lys Ser Gly Gln Glu Lys Gln Thr 
            20                  25                  30          


Ile Glu Ile Leu Met Asn Pro Ile Leu Leu Val Lys Asn Thr Ser Leu 
        35                  40                  45              


Ser Met Ser Lys Asp Asp Met Ser Ser Thr Leu Leu Thr Phe Arg Ser 
    50                  55                  60                  


Leu His Tyr Asn Asp Pro Lys Gly Asn Ser Ser Gly Asn Asp Lys Glu 
65                  70                  75                  80  


Cys Cys Asn Asp Met Thr Val Trp Arg Lys Val Ser Glu Ala Asn Gly 
                85                  90                  95      


Ser Cys Lys Trp Ser Asn Asn Phe Ile Arg Ser Ser Thr Glu Val Met 
            100                 105                 110         


Arg Arg Val His Arg Ala Pro Ser Cys Lys Phe Val Gln Asn Pro Gly 
        115                 120                 125             


Ile Ser Cys Cys Glu Ser Leu Glu Leu Glu Asn Thr Val Cys Gln Phe 
    130                 135                 140                 


Thr Thr Gly Lys Gln Phe Pro Arg Cys Gln Tyr His Ser Val Thr Ser 
145                 150                 155                 160 


Leu Glu Lys Ile Leu Thr Val Leu Thr Gly His Ser Leu Met Ser Trp 
                165                 170                 175     


Leu Val Cys Gly Ser Lys Leu 
            180             


<210>  2696
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  2696

Gln Pro Tyr Trp Ile Gly Asp Ser Val Asn Thr Pro Gln Ala Gly Tyr 
1               5                   10                  15      


Phe Gly Leu Phe Ser Tyr Cys Val Gly Asn Val Leu Ser Ser Glu Leu 
            20                  25                  30          


Ile Cys Lys Gly Gly Pro Leu Asp Phe Ser Ser Ile Pro Ser Arg Ala 
        35                  40                  45              


Phe Lys Thr Ala Met Phe 
    50                  


<210>  2697
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  2697

Tyr Phe Asp Gly Pro Leu Tyr Pro Glu Met Ser Asn Gly Thr Leu His 
1               5                   10                  15      


His Tyr Phe Val Pro Asp Gly Asp Tyr Glu Glu Asn Asp Asp Pro Glu 
            20                  25                  30          


Lys Cys Gln Leu Leu Phe Arg Val Ser Asp His Arg Arg Cys Ser Gln 
        35                  40                  45              


Gly Glu Gly Ser Gln Val Gly Ser Leu Leu Ser Leu Thr Leu Arg Glu 
    50                  55                  60                  


Glu Phe Thr Val Leu Gly Arg Gln Val Glu Asp Ala Gly Arg Val Leu 
65                  70                  75                  80  


Glu Gly Ile Ser Lys Ser Ile Ser Tyr Asp Leu Asp Gly Glu Glu Ser 
                85                  90                  95      


Tyr Gly Lys Tyr Leu Arg Arg Glu Ser His Gln Ile Gly Asp Ala Tyr 
            100                 105                 110         


Ser Asn Ser Asp Lys Ser Leu Thr Glu Leu Glu Ser Lys Phe Lys Gln 
        115                 120                 125             


Gly Gln Glu Gln Asp Ser Arg Gln Glu Ser Arg Leu Asn Glu Asp Phe 
    130                 135                 140                 


Leu Gly Met Leu Val His Thr Arg Ser Leu Leu Lys Glu Thr Leu Asp 
145                 150                 155                 160 


Ile Ser Val Gly Leu Arg Asp Lys Tyr Glu Leu Leu Ala Leu Thr Ile 
                165                 170                 175     


Arg Ser His Gly Thr Arg Leu Gly Arg Leu Lys Asn Asp Tyr Leu Lys 
            180                 185                 190         


Val 
    


<210>  2698
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2698

Ala Ile Ser Trp Glu Leu Asp Asn Val Leu Met Pro Ser Pro Arg Ile 
1               5                   10                  15      


Trp Pro Gln Val Thr Pro Thr Gly Arg Ser Ala Ser Val Arg Ser Glu 
            20                  25                  30          


Gly Asn Thr Ser Ser Leu Trp Asn Phe Ser Ala Gly Gln Asp Val His 
        35                  40                  45              


Ala Ile Val Thr Arg Thr Cys Glu Ser Val Leu Ser Ser Ala Val Tyr 
    50                  55                  60                  


Thr His Gly Cys Gly Cys Val Arg Ser Ala Thr Asn Ile Thr Cys Gln 
65                  70                  75                  80  


Ser Ser Gly Gln Gln Arg Gln Ala Ala Arg Gln Glu Glu Glu Asn Ser 
                85                  90                  95      


Ile Cys Lys Ala His Asp Ser Arg Glu Gly Arg Leu Gly Tyr Pro Leu 
            100                 105                 110         


Ser Ala His Gln Pro Gly Ser Gly Gly Pro Asn 
        115                 120             


<210>  2699
<211>  355
<212>  PRT
<213>  Homo Sapiens

<400>  2699

Arg Glu Arg Asp His Glu Leu Arg His Arg Arg His His His Gln Ser 
1               5                   10                  15      


Pro Lys Ser His Phe Glu Leu Pro His Tyr Pro Gly Leu Leu Ala His 
            20                  25                  30          


Gln Lys Pro Phe Ile Arg Lys Ser Tyr Lys Cys Leu His Lys Arg Cys 
        35                  40                  45              


Arg Pro Lys Leu Pro Pro Ser Pro Asn Asn Pro Pro Lys Phe Pro Asn 
    50                  55                  60                  


Pro His Gln Pro Pro Lys His Pro Asp Lys Asn Ser Ser Val Val Asn 
65                  70                  75                  80  


Pro Thr Leu Val Ala Thr Thr Gln Ile Pro Ser Val Thr Phe Pro Ser 
                85                  90                  95      


Ala Ser Thr Lys Ile Thr Thr Leu Pro Asn Val Thr Phe Leu Pro Gln 
            100                 105                 110         


Asn Ala Thr Thr Ile Ser Ser Arg Glu Asn Val Asn Thr Ser Ser Ser 
        115                 120                 125             


Val Ala Thr Leu Ala Pro Val Asn Ser Pro Ala Pro Gln Asp Thr Thr 
    130                 135                 140                 


Ala Ala Pro Pro Thr Pro Ser Ala Thr Thr Pro Ala Pro Pro Ser Ser 
145                 150                 155                 160 


Ser Ala Pro Pro Glu Thr Thr Ala Ala Pro Pro Thr Pro Ser Ala Thr 
                165                 170                 175     


Thr Gln Ala Pro Pro Ser Ser Ser Ala Pro Pro Glu Thr Thr Ala Ala 
            180                 185                 190         


Pro Pro Thr Pro Pro Ala Thr Thr Pro Ala Pro Pro Ser Ser Ser Ala 
        195                 200                 205             


Pro Pro Glu Thr Thr Ala Ala Pro Pro Thr Pro Ser Ala Thr Thr Pro 
    210                 215                 220                 


Ala Pro Leu Ser Ser Ser Ala Pro Pro Glu Thr Thr Ala Val Pro Pro 
225                 230                 235                 240 


Thr Pro Ser Ala Thr Thr Leu Asp Pro Ser Ser Ala Ser Ala Pro Pro 
                245                 250                 255     


Glu Thr Thr Ala Ala Pro Pro Thr Pro Ser Ala Thr Thr Pro Ala Pro 
            260                 265                 270         


Pro Ser Ser Pro Ala Pro Gln Glu Thr Thr Ala Ala Pro Ile Thr Thr 
        275                 280                 285             


Pro Asn Ser Ser Pro Thr Thr Leu Ala Pro Asp Thr Ser Glu Thr Ser 
    290                 295                 300                 


Ala Ala Pro Thr His Gln Thr Ile Thr Ser Val Thr Thr Gln Thr Thr 
305                 310                 315                 320 


Thr Thr Lys Gln Pro Thr Ser Ala Pro Gly Gln Asn Lys Ile Ser Arg 
                325                 330                 335     


Phe Leu Leu Tyr Met Lys Asn Leu Leu Asn Arg Ile Ile Asp Asp Met 
            340                 345                 350         


Val Glu Gln 
        355 


<210>  2700
<211>  742
<212>  PRT
<213>  Homo Sapiens

<400>  2700

Met Pro Ala Gly Gly Lys Gly Ser His Pro Ser Ser Thr Pro Gln Arg 
1               5                   10                  15      


Val Pro Asn Arg Leu Ile His Glu Lys Ser Pro Tyr Leu Leu Gln His 
            20                  25                  30          


Ala Tyr Asn Pro Val Asp Trp Tyr Pro Trp Gly Glu Glu Ala Phe Asp 
        35                  40                  45              


Lys Ala Arg Lys Glu Asn Lys Pro Ile Phe Leu Ser Val Gly Tyr Ser 
    50                  55                  60                  


Thr Cys His Trp Cys His Met Met Glu Glu Glu Ser Phe Gln Asn Glu 
65                  70                  75                  80  


Glu Ile Gly Arg Leu Leu Ser Glu Asp Phe Val Ser Val Lys Val Asp 
                85                  90                  95      


Arg Glu Glu Arg Pro Asp Val Asp Lys Val Tyr Met Thr Phe Val Gln 
            100                 105                 110         


Ala Thr Ser Ser Gly Gly Gly Trp Pro Met Asn Val Trp Leu Thr Pro 
        115                 120                 125             


Asn Leu Gln Pro Phe Val Gly Gly Thr Tyr Phe Pro Pro Glu Asp Gly 
    130                 135                 140                 


Leu Thr Arg Val Gly Phe Arg Thr Val Leu Leu Arg Ile Arg Glu Gln 
145                 150                 155                 160 


Trp Lys Gln Asn Lys Asn Thr Leu Leu Glu Asn Ser Gln Arg Val Thr 
                165                 170                 175     


Thr Ala Leu Leu Ala Arg Ser Glu Ile Ser Val Gly Asp Arg Gln Leu 
            180                 185                 190         


Pro Pro Ser Ala Ala Thr Val Asn Asn Arg Cys Phe Gln Gln Leu Asp 
        195                 200                 205             


Glu Gly Tyr Asp Glu Glu Tyr Gly Gly Phe Ala Glu Ala Pro Lys Phe 
    210                 215                 220                 


Pro Thr Pro Val Ile Leu Ser Phe Leu Phe Ser Tyr Trp Leu Ser His 
225                 230                 235                 240 


Arg Leu Thr Gln Asp Gly Ser Arg Ala Gln Gln Met Ala Leu His Thr 
                245                 250                 255     


Leu Lys Met Met Ala Asn Gly Gly Ile Arg Asp His Val Gly Gln Gly 
            260                 265                 270         


Phe His Arg Tyr Ser Thr Asp Arg Gln Trp His Val Pro His Phe Glu 
        275                 280                 285             


Lys Met Leu Tyr Asp Gln Ala Gln Leu Ala Val Ala Tyr Ser Gln Ala 
    290                 295                 300                 


Phe Gln Leu Ser Gly Asp Glu Phe Tyr Ser Asp Val Ala Lys Gly Ile 
305                 310                 315                 320 


Leu Gln Tyr Val Ala Arg Ser Leu Ser His Arg Ser Gly Gly Phe Tyr 
                325                 330                 335     


Ser Ala Glu Asp Ala Asp Ser Pro Pro Glu Arg Gly Gln Arg Pro Lys 
            340                 345                 350         


Glu Gly Ala Tyr Tyr Val Trp Thr Val Lys Glu Val Gln Gln Leu Leu 
        355                 360                 365             


Pro Glu Pro Val Leu Gly Ala Thr Glu Pro Leu Thr Ser Gly Gln Leu 
    370                 375                 380                 


Leu Met Lys His Tyr Gly Leu Thr Glu Ala Gly Asn Ile Ser Pro Ser 
385                 390                 395                 400 


Gln Asp Pro Lys Gly Glu Leu Gln Gly Gln Asn Val Leu Thr Val Arg 
                405                 410                 415     


Tyr Ser Leu Glu Leu Thr Ala Ala Arg Phe Gly Leu Asp Val Glu Ala 
            420                 425                 430         


Val Arg Thr Leu Leu Asn Thr Gly Leu Glu Lys Leu Phe Gln Ala Arg 
        435                 440                 445             


Lys His Arg Pro Lys Pro His Leu Asp Ser Lys Met Leu Ala Ala Trp 
    450                 455                 460                 


Asn Gly Leu Met Val Ser Gly Tyr Ala Val Thr Gly Ala Val Leu Gly 
465                 470                 475                 480 


Gln Asp Arg Leu Ile Asn Tyr Ala Thr Asn Gly Ala Lys Phe Leu Lys 
                485                 490                 495     


Arg His Met Phe Asp Val Ala Ser Gly Arg Leu Met Arg Thr Cys Tyr 
            500                 505                 510         


Thr Gly Pro Gly Gly Thr Val Glu His Ser Asn Pro Pro Cys Trp Gly 
        515                 520                 525             


Phe Leu Glu Asp Tyr Ala Phe Val Val Arg Gly Leu Leu Asp Leu Tyr 
    530                 535                 540                 


Glu Ala Ser Gln Glu Ser Ala Trp Leu Glu Trp Ala Leu Arg Leu Gln 
545                 550                 555                 560 


Asp Thr Gln Asp Arg Leu Phe Trp Asp Ser Gln Gly Gly Gly Tyr Phe 
                565                 570                 575     


Cys Ser Glu Ala Glu Leu Gly Ala Gly Leu Pro Leu Arg Leu Lys Asp 
            580                 585                 590         


Asp Gln Asp Gly Ala Glu Pro Ser Ala Asn Ser Val Ser Ala His Asn 
        595                 600                 605             


Leu Leu Arg Leu His Gly Phe Thr Gly His Lys Asp Trp Met Asp Lys 
    610                 615                 620                 


Cys Val Cys Leu Leu Thr Ala Phe Ser Glu Arg Met Arg Arg Val Pro 
625                 630                 635                 640 


Val Ala Leu Pro Glu Met Val Arg Ala Leu Ser Ala Gln Gln Gln Thr 
                645                 650                 655     


Leu Lys Gln Ile Val Ile Cys Gly Asp Arg Gln Ala Lys Asp Thr Lys 
            660                 665                 670         


Ala Leu Val Gln Cys Val His Ser Val Tyr Ile Pro Asn Lys Val Leu 
        675                 680                 685             


Ile Leu Ala Asp Gly Asp Pro Ser Ser Phe Leu Ser Arg Gln Leu Pro 
    690                 695                 700                 


Phe Leu Ser Thr Leu Arg Arg Leu Glu Asp Gln Ala Thr Ala Tyr Val 
705                 710                 715                 720 


Cys Glu Asn Gln Ala Cys Ser Val Pro Ile Thr Asp Pro Cys Glu Leu 
                725                 730                 735     


Arg Lys Leu Leu His Pro 
            740         


<210>  2701
<211>  533
<212>  PRT
<213>  Homo Sapiens

<400>  2701

Leu His Asn Val Thr Ala Glu Leu Phe Gly Ala Glu Ala Trp Gly Thr 
1               5                   10                  15      


Leu Ala Ala Phe Gly Asp Leu Asn Ser Asp Lys Gln Thr Asp Leu Phe 
            20                  25                  30          


Val Leu Arg Glu Arg Asn Asp Leu Ile Val Phe Leu Ala Asp Gln Asn 
        35                  40                  45              


Ala Pro Tyr Phe Lys Pro Lys Val Lys Val Ser Phe Lys Asn His Ser 
    50                  55                  60                  


Ala Leu Ile Thr Ser Val Val Pro Gly Asp Tyr Asp Gly Asp Ser Gln 
65                  70                  75                  80  


Met Asp Val Leu Leu Thr Tyr Leu Pro Lys Asn Tyr Ala Lys Ser Glu 
                85                  90                  95      


Leu Gly Ala Val Ile Phe Trp Gly Gln Asn Gln Thr Leu Asp Pro Asn 
            100                 105                 110         


Asn Met Thr Ile Leu Asn Arg Thr Phe Gln Asp Glu Pro Leu Ile Met 
        115                 120                 125             


Asp Phe Asn Gly Asp Leu Ile Pro Asp Ile Phe Gly Ile Thr Asn Glu 
    130                 135                 140                 


Ser Asn Gln Pro Gln Ile Leu Leu Gly Gly Asn Leu Ser Trp His Pro 
145                 150                 155                 160 


Ala Leu Thr Thr Thr Ser Lys Met Arg Ile Pro His Ser His Ala Phe 
                165                 170                 175     


Ile Asp Leu Thr Glu Asp Phe Thr Ala Asp Leu Phe Leu Thr Thr Leu 
            180                 185                 190         


Asn Ala Thr Thr Ser Thr Phe Gln Phe Glu Ile Trp Glu Asn Leu Asp 
        195                 200                 205             


Gly Asn Phe Ser Val Ser Thr Ile Leu Glu Lys Pro Gln Asn Met Met 
    210                 215                 220                 


Val Val Gly Gln Ser Ala Phe Ala Asp Phe Asp Gly Asp Gly His Met 
225                 230                 235                 240 


Asp His Leu Leu Pro Gly Cys Glu Asp Lys Asn Cys Gln Lys Ser Thr 
                245                 250                 255     


Ile Tyr Leu Val Arg Ser Gly Met Lys Gln Trp Val Pro Val Leu Gln 
            260                 265                 270         


Asp Phe Ser Asn Lys Gly Thr Leu Trp Gly Phe Val Pro Phe Val Asp 
        275                 280                 285             


Glu Gln Gln Pro Thr Glu Ile Pro Ile Pro Ile Thr Leu His Ile Gly 
    290                 295                 300                 


Asp Tyr Asn Met Asp Gly Tyr Pro Asp Ala Leu Val Ile Leu Lys Asn 
305                 310                 315                 320 


Thr Ser Gly Ser Asn Gln Gln Ala Phe Leu Leu Glu Asn Val Pro Cys 
                325                 330                 335     


Asn Asn Ala Ser Cys Glu Glu Ala Arg Arg Met Phe Lys Val Tyr Trp 
            340                 345                 350         


Glu Leu Thr Asp Leu Asn Gln Ile Lys Asp Ala Met Val Ala Thr Phe 
        355                 360                 365             


Phe Asp Ile Tyr Glu Asp Gly Ile Leu Asp Ile Val Val Leu Ser Lys 
    370                 375                 380                 


Gly Tyr Thr Lys Asn Asp Phe Ala Ile His Thr Leu Lys Asn Asn Phe 
385                 390                 395                 400 


Glu Ala Asp Ala Tyr Phe Val Lys Val Ile Val Leu Ser Gly Leu Cys 
                405                 410                 415     


Ser Asn Asp Cys Pro Arg Lys Ile Thr Pro Phe Gly Val Asn Gln Pro 
            420                 425                 430         


Gly Pro Tyr Ile Met Tyr Thr Thr Val Asp Ala Asn Gly Tyr Leu Lys 
        435                 440                 445             


Asn Gly Ser Ala Gly Gln Leu Ser Gln Ser Ala His Leu Ala Leu Gln 
    450                 455                 460                 


Leu Pro Tyr Asn Val Leu Gly Leu Gly Arg Ser Ala Asn Phe Leu Asp 
465                 470                 475                 480 


His Leu Tyr Val Gly Ile Pro Arg Pro Ser Gly Glu Lys Ser Ile Arg 
                485                 490                 495     


Lys Gln Glu Trp Thr Ala Ile Ile Pro Asn Ser Gln Leu Ile Val Ile 
            500                 505                 510         


Pro Tyr Pro His Asn Val Pro Arg Ser Trp Ser Ala Lys Leu Tyr Leu 
        515                 520                 525             


Thr Pro Ser Asn Ile 
    530             


<210>  2702
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2702

Leu Ala Val Leu Leu Gln Ala Ala Glu Ala Ala Pro Gly Leu Gly Pro 
1               5                   10                  15      


Pro Asp Pro Arg Pro Arg Thr Leu Pro Pro Leu Pro Pro Gly Pro Thr 
            20                  25                  30          


Pro Ala Gln Gln Pro Gly Arg Gly Leu Ala Glu Ala Ala Gly Pro Arg 
        35                  40                  45              


Gly Ser Glu Gly Gly Asn Gly Ser Asn Pro Val Ala Gly Leu Glu Thr 
    50                  55                  60                  


Asp Asp His Gly Gly Lys Ala Gly Glu Gly Ser Val Gly Gly Gly Leu 
65                  70                  75                  80  


Ala Val Ser Pro Asn Pro Gly Asp Lys Pro Met Thr Gln Arg 
                85                  90                  


<210>  2703
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  2703

Met Ala Asn His Asn Leu Leu Gln Ile Phe Thr Ala Ala Thr Pro Val 
1               5                   10                  15      


His His Cys Arg Pro Pro His Asn Ala Ser Thr Gly Pro Trp Val Leu 
            20                  25                  30          


Pro Met Gly Pro Asn Gly Lys Pro Glu Arg Cys Leu Arg Phe Val His 
        35                  40                  45              


Pro Pro Asn Ala Ser Leu Pro Asn Asp Thr Gln Arg Ala Met Glu Pro 
    50                  55                  60                  


Cys Leu Asp Gly Trp Val Tyr Asn Ser Thr Lys Asp Ser Ile Val Thr 
65                  70                  75                  80  


Glu Trp Asp Leu Val Cys Asn Ser Asn Lys Leu Lys Glu 
                85                  90              


<210>  2704
<211>  513
<212>  PRT
<213>  Homo Sapiens

<400>  2704

Met Thr Pro Glu Ser Arg Asp Thr Thr Asp Leu Ser Pro Gly Gly Thr 
1               5                   10                  15      


Gln Glu Met Glu Gly Ile Val Ile Val Lys Val Glu Glu Glu Asp Glu 
            20                  25                  30          


Glu Asp His Phe Gln Lys Glu Arg Asn Lys Val Glu Ser Ser Pro Gln 
        35                  40                  45              


Val Leu Ser Arg Ser Thr Thr Met Asn Glu Arg Ala Leu Leu Ser Ser 
    50                  55                  60                  


Tyr Leu Val Ala Tyr Arg Val Ala Lys Glu Lys Met Ala His Thr Ala 
65                  70                  75                  80  


Ala Glu Lys Ile Ile Leu Pro Ala Cys Met Asp Met Val Arg Thr Ile 
                85                  90                  95      


Phe Asp Asp Lys Ser Ala Asp Lys Leu Arg Thr Ile Pro Leu Ser Asp 
            100                 105                 110         


Asn Thr Ile Ser Arg Arg Ile Cys Thr Ile Ala Lys His Leu Glu Ala 
        115                 120                 125             


Met Leu Ile Thr Arg Leu Gln Ser Gly Ile Asp Phe Ala Ile Gln Leu 
    130                 135                 140                 


Asp Glu Ser Thr Asp Ile Ala Ser Cys Pro Thr Leu Leu Val Tyr Val 
145                 150                 155                 160 


Arg Tyr Val Trp Gln Asp Asp Phe Val Glu Asp Leu Leu Cys Cys Leu 
                165                 170                 175     


Asn Leu Asn Ser His Ile Thr Gly Leu Asp Leu Phe Thr Glu Leu Glu 
            180                 185                 190         


Asn Cys Leu Leu Gly Gln Tyr Lys Leu Asn Trp Lys His Cys Lys Gly 
        195                 200                 205             


Ile Ser Ser Asp Gly Thr Ala Asn Met Thr Gly Lys His Ser Arg Leu 
    210                 215                 220                 


Thr Glu Lys Leu Leu Glu Ala Thr His Asn Asn Ala Val Trp Asn His 
225                 230                 235                 240 


Cys Phe Ile His Arg Glu Ala Leu Val Ser Lys Glu Ile Ser Pro Ser 
                245                 250                 255     


Leu Met Asp Val Leu Lys Asn Ala Val Lys Thr Val Asn Phe Ile Lys 
            260                 265                 270         


Gly Ser Ser Leu Asn Ser Arg Leu Leu Glu Ile Phe Cys Ser Glu Ile 
        275                 280                 285             


Gly Val Asn His Thr His Leu Leu Phe His Thr Glu Val Arg Trp Leu 
    290                 295                 300                 


Ser Gln Gly Lys Val Leu Ser Arg Val Tyr Glu Leu Arg Asn Glu Ile 
305                 310                 315                 320 


Tyr Ile Phe Leu Val Glu Lys Gln Ser His Leu Ala Asn Ile Phe Glu 
                325                 330                 335     


Asp Asp Ile Trp Val Thr Lys Leu Ala Tyr Leu Ser Asp Ile Phe Gly 
            340                 345                 350         


Ile Leu Asn Glu Leu Ser Leu Lys Met Gln Gly Lys Asn Asn Asp Ile 
        355                 360                 365             


Phe Gln Tyr Leu Glu His Ile Leu Gly Phe Gln Lys Thr Leu Leu Leu 
    370                 375                 380                 


Trp Gln Ala Arg Leu Lys Ser Asn Arg Pro Ser Tyr Tyr Met Phe Pro 
385                 390                 395                 400 


Thr Leu Leu Gln His Ile Glu Glu Asn Ile Ile Asn Glu Asp Cys Leu 
                405                 410                 415     


Lys Glu Ile Lys Leu Glu Ile Leu Leu His Leu Thr Ser Leu Ser Gln 
            420                 425                 430         


Thr Phe Asn Tyr Tyr Phe Pro Glu Glu Lys Phe Glu Ser Leu Lys Glu 
        435                 440                 445             


Asn Ile Trp Met Lys Asp Pro Phe Ala Phe Gln Asn Pro Glu Ser Ile 
    450                 455                 460                 


Ile Glu Leu Asn Leu Glu Pro Glu Glu Glu Asn Glu Leu Leu Gln Leu 
465                 470                 475                 480 


Ser Ser Ser Phe Thr Leu Lys Asn Tyr Tyr Lys Ile Leu Ser Leu Ser 
                485                 490                 495     


Ala Phe Trp Ile Lys Ile Lys Asp Asp Phe Pro Leu Leu Ser Arg Lys 
            500                 505                 510         


Ser 
    


<210>  2705
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  2705

Gln Phe Asn Gly Tyr Asn Cys Asp Ala Asn Leu His Ser Arg Phe Pro 
1               5                   10                  15      


Ala Glu Arg Asp Ile Ser Val Tyr Cys Gly Val Gln Ala Ile Thr Met 
            20                  25                  30          


Lys Ile Asn Phe Cys Thr Val Leu Phe Ser Gly Tyr Ser Glu Thr Asp 
        35                  40                  45              


Leu Ala Leu Asn Gly Arg His Gly Asp Ser His Cys Arg Gly Phe Ile 
    50                  55                  60                  


Asn Asn Asn Thr Phe Pro Ala Val Val Ile Phe Ile Ile Asn Leu Ser 
65                  70                  75                  80  


Thr Leu Glu Gly Cys Gly Asn Asn Leu Val Val Ser Thr Ile Pro Gly 
                85                  90                  95      


Val Ser Ala Tyr Gly Asn Ala Thr Ser Val Gln Val Gly Asn Ile Ser 
            100                 105                 110         


Gly Tyr Ile Asp Thr Pro Asp Pro Pro Thr Ile Ile Ser Tyr Leu Pro 
        115                 120                 125             


Gly Leu Leu Tyr Lys Phe Ser Cys Ser Tyr Pro Leu Glu Tyr Leu Val 
    130                 135                 140                 


Asn Asn Thr Gln Leu Ala Ser Ser Ser Ala Ala Ile Ser Val Arg Glu 
145                 150                 155                 160 


Asn Asn Gly Thr Phe Val Ser Thr Leu Asn Leu Leu Leu Tyr Asn Asp 
                165                 170                 175     


Ser Thr Tyr Asn Gln Gln Leu Ile Ile Pro Ser Ile Gly Leu Pro Leu 
            180                 185                 190         


Lys Thr Lys Val Phe Ala Ala Val Gln Ala Thr Asn Leu Asp Gly Arg 
        195                 200                 205             


Trp Asn Val Leu Met Asp Tyr Cys Tyr Thr Thr Pro Ser Gly Ser Pro 
    210                 215                 220                 


Asn Asp Asp Ile Arg Tyr Asp Leu Phe Leu Ser Cys Asp Lys Asp Pro 
225                 230                 235                 240 


Gln Thr Thr Val Ile Glu Asn Gly Arg Ser Gln Arg Gly Arg Phe Ser 
                245                 250                 255     


Phe Glu Val Phe Arg Phe Val Lys His Lys Asn Gln Lys Met Ser Thr 
            260                 265                 270         


Val Phe Leu His Cys Val Thr Lys Leu Cys Arg Ala Asp Asp Cys Pro 
        275                 280                 285             


Phe Leu Met Pro Ile Cys Ser His Arg Glu Arg Arg 
    290                 295                 300 


<210>  2706
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  2706

Met Glu Thr Thr Met Gly Phe Met Asp Asp Asn Ala Thr Asn Thr Ser 
1               5                   10                  15      


Thr Ser Phe Leu Ser Val Leu Asn Pro His Gly Ala His Ala Thr Ser 
            20                  25                  30          


Phe Pro Phe Asn Phe Ser Tyr Ser Asp Tyr Asp Met Pro Leu Asp Glu 
        35                  40                  45              


Asp Glu Asp Val Thr Asn Ser Arg Thr Phe Phe Ala Ala Lys 
    50                  55                  60          


<210>  2707
<211>  160
<212>  PRT
<213>  Homo Sapiens

<400>  2707

Asp Phe Asp Asp Phe Asn Leu Glu Asp Ala Val Lys Glu Thr Ser Ser 
1               5                   10                  15      


Val Lys Gln Pro Trp Asp His Thr Thr Thr Thr Thr Thr Asn Arg Pro 
            20                  25                  30          


Gly Thr Thr Arg Ala Pro Ala Lys Pro Pro Gly Ser Gly Leu Asp Leu 
        35                  40                  45              


Ala Asp Ala Leu Asp Asp Gln Asp Asp Gly Arg Arg Lys Pro Gly Ile 
    50                  55                  60                  


Gly Gly Arg Glu Arg Trp Asn His Val Thr Thr Thr Thr Lys Arg Pro 
65                  70                  75                  80  


Val Thr Thr Arg Ala Pro Ala Asn Thr Leu Gly Asn Asp Phe Asp Leu 
                85                  90                  95      


Ala Asp Ala Leu Asp Asp Arg Asn Asp Arg Asp Asp Gly Arg Arg Lys 
            100                 105                 110         


Pro Ile Ala Gly Gly Gly Gly Phe Ser Asp Lys Asp Leu Glu Asp Ile 
        115                 120                 125             


Val Gly Gly Gly Glu Tyr Lys Pro Asp Lys Gly Lys Gly Asp Gly Arg 
    130                 135                 140                 


Tyr Gly Ser Asn Asp Asp Pro Gly Ser Gly Met Val Ala Glu Pro Gly 
145                 150                 155                 160 


<210>  2708
<211>  145
<212>  PRT
<213>  Homo Sapiens

<400>  2708

Ile Ala Ile Lys Lys Glu Lys Arg Pro Pro Gln Thr Leu Ser Arg Gly 
1               5                   10                  15      


Trp Gly Asp Asp Ile Thr Trp Val Gln Thr Tyr Glu Glu Gly Leu Phe 
            20                  25                  30          


Tyr Ala Gln Lys Ser Lys Lys Pro Leu Met Val Ile His His Leu Glu 
        35                  40                  45              


Asp Cys Gln Tyr Ser Gln Ala Leu Lys Lys Val Phe Ala Gln Asn Glu 
    50                  55                  60                  


Glu Ile Gln Glu Met Ala Gln Asn Lys Phe Ile Met Leu Asn Leu Met 
65                  70                  75                  80  


His Glu Thr Thr Asp Lys Asn Leu Ser Pro Asp Gly Gln Tyr Val Pro 
                85                  90                  95      


Arg Ile Met Phe Val Asp Pro Ser Leu Thr Val Arg Ala Asp Ile Ala 
            100                 105                 110         


Gly Arg Tyr Ser Asn Arg Leu Tyr Thr Tyr Glu Pro Arg Asp Leu Pro 
        115                 120                 125             


Leu Leu Ile Glu Asn Met Lys Lys Ala Leu Arg Leu Ile Gln Ser Glu 
    130                 135                 140                 


Leu 
145 


<210>  2709
<211>  195
<212>  PRT
<213>  Homo Sapiens

<400>  2709

His Ser Leu Cys Phe Asn Phe Thr Ile Lys Ser Leu Ser Arg Pro Gly 
1               5                   10                  15      


Gln Pro Trp Cys Glu Ala Gln Val Phe Leu Asn Lys Asn Leu Phe Leu 
            20                  25                  30          


Gln Tyr Asn Ser Asp Asn Asn Met Val Lys Pro Leu Gly Leu Leu Gly 
        35                  40                  45              


Lys Lys Val Asn Ala Thr Ser Thr Trp Gly Glu Leu Thr Gln Thr Leu 
    50                  55                  60                  


Gly Glu Val Gly Arg Asp Leu Arg Met Leu Leu Cys Asp Ile Lys Pro 
65                  70                  75                  80  


Gln Ile Lys Thr Ser Asp Pro Ser Thr Leu Gln Val Glu Met Phe Cys 
                85                  90                  95      


Gln His Glu Ala Glu Arg Cys Thr Gly Ala Ser Trp Gln Phe Thr Ile 
            100                 105                 110         


Asn Gly Glu Lys Ser Leu Leu Phe Asp Ala Met Asn Met Thr Trp Thr 
        115                 120                 125             


Val Ile Asn His Glu Ala Ser Lys Ile Lys Glu Thr Trp Lys Lys Asp 
    130                 135                 140                 


Arg Gly Leu Glu Lys Tyr Phe Arg Lys Leu Ser Lys Gly Asp Cys Asp 
145                 150                 155                 160 


His Trp Leu Arg Glu Phe Leu Gly His Trp Glu Ala Met Pro Glu Pro 
                165                 170                 175     


Thr Val Ser Pro Val Asn Ala Ser Asp Ile His Trp Ser Ser Ser Ser 
            180                 185                 190         


Leu Pro Asp 
        195 


<210>  2710
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  2710

Asn Ile His Met Asn Phe Thr His Ile Cys Arg Ser His Asn Ser Ile 
1               5                   10                  15      


Asn Gln Ser Leu Asp Glu Ser Val Ile Tyr Gly Pro Gly Asn Leu Ser 
            20                  25                  30          


Thr Asn Asn Asn Thr Leu Arg Asp His Phe Lys Gly Ile Ser Ser His 
        35                  40                  45              


Ser Arg Ser Ser Leu Met Pro Leu Arg Asn Asp Val Asp Lys Arg Gly 
    50                  55                  60                  


Glu Thr Thr Ser Ala Ser Leu Leu Asn Ala Gly Leu Ser His Thr Glu 
65                  70                  75                  80  


Tyr Gln Ile Val Thr Asp Pro Gly Asp Val Pro Ala Phe Leu Lys Trp 
                85                  90                  95      


Leu Ser Leu Ala 
            100 


<210>  2711
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2711

Lys Pro Lys Asp Met Thr Ser Ser Gln Trp Phe Lys Thr Gln His Val 
1               5                   10                  15      


Gln Pro Ser Pro Gln Ala Cys Asn Ser Ala Met Ser Ile Ile Asn Lys 
            20                  25                  30          


Tyr Thr Glu Arg Cys Lys Asp Leu Asn Thr Phe Leu His Glu Pro Phe 
        35                  40                  45              


Ser Ser Val Ala Ile Thr Cys Gln Thr Pro Asn Ile Ala Cys Lys Asn 
    50                  55                  60                  


Ser Cys Lys Asn Cys His Gln Ser His Gly Pro Met Ser Leu Thr Met 
65                  70                  75                  80  


Gly Glu Leu Thr Ser Gly Lys Tyr Pro Asn Cys Arg Tyr Lys Glu Lys 
                85                  90                  95      


His Leu Asn Thr Pro Tyr Ile Val Ala Cys Asp Pro Pro Gln Gln Gly 
            100                 105                 110         


Asp Pro Gly Tyr Pro Leu Val Pro Val His Leu Asp Lys Val Val 
        115                 120                 125         


<210>  2712
<211>  463
<212>  PRT
<213>  Homo Sapiens

<400>  2712

Thr Leu Ser Pro Thr Ala Val Leu Ile Leu Gly Pro Lys Val Ile Lys 
1               5                   10                  15      


Glu Lys Leu Thr Gln Glu Leu Lys Asp His Asn Ala Thr Ser Ile Leu 
            20                  25                  30          


Gln Gln Leu Pro Leu Leu Ser Ala Met Arg Glu Lys Pro Ala Gly Gly 
        35                  40                  45              


Ile Pro Val Leu Gly Ser Leu Val Asn Thr Val Leu Lys His Val Ile 
    50                  55                  60                  


Trp Leu Lys Val Ile Thr Ala Asn Ile Leu Gln Leu Gln Val Lys Pro 
65                  70                  75                  80  


Ser Ala Asn Asp Gln Glu Leu Leu Val Lys Ile Pro Leu Asp Met Val 
                85                  90                  95      


Ala Gly Phe Asn Thr Pro Leu Val Lys Thr Ile Val Glu Phe His Met 
            100                 105                 110         


Thr Thr Glu Ala Gln Ala Thr Ile Arg Met Asp Thr Ser Ala Ser Gly 
        115                 120                 125             


Pro Thr Arg Leu Val Leu Ser Asp Cys Ala Thr Ser His Gly Ser Leu 
    130                 135                 140                 


Arg Ile Gln Leu Leu His Lys Leu Ser Phe Leu Val Asn Ala Leu Ala 
145                 150                 155                 160 


Lys Gln Val Met Asn Leu Leu Val Pro Ser Leu Pro Asn Leu Val Lys 
                165                 170                 175     


Asn Gln Leu Cys Pro Val Ile Glu Ala Ser Phe Asn Gly Met Tyr Ala 
            180                 185                 190         


Asp Leu Leu Gln Leu Val Lys Val Pro Ile Ser Leu Ser Ile Asp Arg 
        195                 200                 205             


Leu Glu Phe Asp Leu Leu Tyr Pro Ala Ile Lys Gly Asp Thr Ile Gln 
    210                 215                 220                 


Leu Tyr Leu Gly Ala Lys Leu Leu Asp Ser Gln Gly Lys Val Thr Lys 
225                 230                 235                 240 


Trp Phe Asn Asn Ser Ala Ala Ser Leu Thr Met Pro Thr Leu Asp Asn 
                245                 250                 255     


Ile Pro Phe Ser Leu Ile Val Ser Gln Asp Val Val Lys Ala Ala Val 
            260                 265                 270         


Ala Ala Val Leu Ser Pro Glu Glu Phe Met Val Leu Leu Asp Ser Val 
        275                 280                 285             


Leu Pro Glu Ser Ala His Arg Leu Lys Ser Ser Ile Gly Leu Ile Asn 
    290                 295                 300                 


Glu Lys Ala Ala Asp Lys Leu Gly Ser Thr Gln Ile Val Lys Ile Leu 
305                 310                 315                 320 


Thr Gln Asp Thr Pro Glu Phe Phe Ile Asp Gln Gly His Ala Lys Val 
                325                 330                 335     


Ala Gln Leu Ile Val Leu Glu Val Phe Pro Ser Ser Glu Ala Leu Arg 
            340                 345                 350         


Pro Leu Phe Thr Leu Gly Ile Glu Ala Ser Ser Glu Ala Gln Phe Tyr 
        355                 360                 365             


Thr Lys Gly Asp Gln Leu Ile Leu Asn Leu Asn Asn Ile Ser Ser Asp 
    370                 375                 380                 


Arg Ile Gln Leu Met Asn Ser Gly Ile Gly Trp Phe Gln Pro Asp Val 
385                 390                 395                 400 


Leu Lys Asn Ile Ile Thr Glu Ile Ile His Ser Ile Leu Leu Pro Asn 
                405                 410                 415     


Gln Asn Gly Lys Leu Arg Ser Gly Val Pro Val Ser Leu Val Lys Ala 
            420                 425                 430         


Leu Gly Phe Glu Ala Ala Glu Ser Ser Leu Ser Lys Asp Ala Leu Val 
        435                 440                 445             


Leu Thr Pro Ala Ser Leu Trp Lys Pro Thr Ser Pro Val Ser Gln 
    450                 455                 460             


<210>  2713
<211>  85
<212>  PRT
<213>  Homo Sapiens

<400>  2713

Cys Pro Arg Arg Phe Leu Glu Glu Leu Gly Tyr Trp Gly Val Arg Leu 
1               5                   10                  15      


Lys Tyr Thr Pro Arg Cys Cys Arg Ile Cys Phe Glu Glu Arg Arg Asp 
            20                  25                  30          


Glu Leu Ser Glu Arg Leu Lys Ile Gln His Glu Leu Arg Ala Gln Ala 
        35                  40                  45              


Gln Val Glu Glu Ala Glu Glu Leu Phe Arg Asp Met Arg Phe Tyr Gly 
    50                  55                  60                  


Pro Gln Arg Arg Arg Leu Trp Asn Leu Met Glu Lys Pro Phe Ser Ser 
65                  70                  75                  80  


Val Ala Ala Lys Ala 
                85  


<210>  2714
<211>  547
<212>  PRT
<213>  Homo Sapiens

<400>  2714

Glu Pro Ala Glu Asn Ser Asp Phe Tyr Leu Pro Gly Asp Tyr Leu Leu 
1               5                   10                  15      


Gly Gly Leu Phe Ser Leu His Ala Asn Met Lys Gly Ile Val His Leu 
            20                  25                  30          


Asn Phe Leu Gln Val Pro Met Cys Lys Glu Tyr Glu Val Lys Val Ile 
        35                  40                  45              


Gly Tyr Asn Leu Met Gln Ala Met Arg Phe Ala Val Glu Glu Ile Asn 
    50                  55                  60                  


Asn Asp Ser Ser Leu Leu Pro Gly Val Leu Leu Gly Tyr Glu Ile Val 
65                  70                  75                  80  


Asp Val Cys Tyr Ile Ser Asn Asn Val Gln Pro Val Leu Tyr Phe Leu 
                85                  90                  95      


Ala His Glu Asp Asn Leu Leu Pro Ile Gln Glu Asp Tyr Ser Asn Tyr 
            100                 105                 110         


Ile Ser Arg Val Val Ala Val Ile Gly Pro Asp Asn Ser Glu Ser Val 
        115                 120                 125             


Met Thr Val Ala Asn Phe Leu Ser Leu Phe Leu Leu Pro Gln Ile Thr 
    130                 135                 140                 


Tyr Ser Ala Ile Ser Asp Glu Leu Arg Asp Lys Val Arg Phe Pro Ala 
145                 150                 155                 160 


Leu Leu Arg Thr Thr Pro Ser Ala Asp His His Ile Glu Ala Met Val 
                165                 170                 175     


Gln Leu Met Leu His Phe Arg Trp Asn Trp Ile Ile Val Leu Val Ser 
            180                 185                 190         


Ser Asp Thr Tyr Gly Arg Asp Asn Gly Gln Leu Leu Gly Glu Arg Val 
        195                 200                 205             


Ala Arg Arg Asp Ile Cys Ile Ala Phe Gln Glu Thr Leu Pro Thr Leu 
    210                 215                 220                 


Gln Pro Asn Gln Asn Met Thr Ser Glu Glu Arg Gln Arg Leu Val Thr 
225                 230                 235                 240 


Ile Val Asp Lys Leu Gln Gln Ser Thr Ala Arg Val Val Val Val Phe 
                245                 250                 255     


Ser Pro Asp Leu Thr Leu Tyr His Phe Phe Asn Glu Val Leu Arg Gln 
            260                 265                 270         


Asn Phe Thr Gly Ala Val Trp Ile Ala Ser Glu Ser Trp Ala Ile Asp 
        275                 280                 285             


Pro Val Leu His Asn Leu Thr Glu Leu Arg His Leu Gly Thr Phe Leu 
    290                 295                 300                 


Gly Ile Thr Ile Gln Ser Val Pro Ile Pro Gly Phe Ser Glu Phe Arg 
305                 310                 315                 320 


Glu Trp Gly Pro Gln Ala Gly Pro Pro Pro Leu Ser Arg Thr Ser Gln 
                325                 330                 335     


Ser Tyr Thr Cys Asn Gln Glu Cys Asp Asn Cys Leu Asn Ala Thr Leu 
            340                 345                 350         


Ser Phe Asn Thr Ile Leu Arg Leu Ser Gly Glu Arg Val Val Tyr Ser 
        355                 360                 365             


Val Tyr Ser Ala Val Tyr Ala Val Ala His Ala Leu His Ser Leu Leu 
    370                 375                 380                 


Gly Cys Asp Lys Ser Thr Cys Thr Lys Arg Val Val Tyr Pro Trp Gln 
385                 390                 395                 400 


Leu Leu Glu Glu Ile Trp Lys Val Asn Phe Thr Leu Leu Asp His Gln 
                405                 410                 415     


Ile Phe Phe Asp Pro Gln Gly Asp Val Ala Leu His Leu Glu Ile Val 
            420                 425                 430         


Gln Trp Gln Trp Asp Arg Ser Gln Asn Pro Phe Gln Ser Val Ala Ser 
        435                 440                 445             


Tyr Tyr Pro Leu Gln Arg Gln Leu Lys Asn Ile Gln Asp Ile Ser Trp 
    450                 455                 460                 


His Thr Ile Asn Asn Thr Ile Pro Met Ser Met Cys Ser Lys Arg Cys 
465                 470                 475                 480 


Gln Ser Gly Gln Lys Lys Lys Pro Val Gly Ile His Val Cys Cys Phe 
                485                 490                 495     


Glu Cys Ile Asp Cys Leu Pro Gly Thr Phe Leu Asn His Thr Glu Asp 
            500                 505                 510         


Glu Tyr Glu Cys Gln Ala Cys Pro Asn Asn Glu Trp Ser Tyr Gln Ser 
        515                 520                 525             


Glu Thr Ser Cys Phe Lys Arg Gln Leu Val Phe Leu Glu Trp His Glu 
    530                 535                 540                 


Ala Pro Thr 
545         


<210>  2715
<211>  872
<212>  PRT
<213>  Homo Sapiens

<400>  2715

Asn Ala Ile Arg Leu Thr Ser Glu His Thr Val Glu Thr Leu Val Val 
1               5                   10                  15      


Ala Asp Ala Asp Met Val Gln Tyr His Gly Ala Glu Ala Ala Gln Arg 
            20                  25                  30          


Phe Ile Leu Thr Val Met Asn Met Val Tyr Asn Met Phe Gln His Gln 
        35                  40                  45              


Ser Leu Gly Ile Lys Ile Asn Ile Gln Val Thr Lys Leu Val Leu Leu 
    50                  55                  60                  


Arg Gln Arg Pro Ala Lys Leu Ser Ile Gly His His Gly Glu Arg Ser 
65                  70                  75                  80  


Leu Glu Ser Phe Cys His Trp Gln Asn Glu Glu Tyr Gly Gly Ala Arg 
                85                  90                  95      


Tyr Leu Gly Asn Asn Gln Val Pro Gly Gly Lys Asp Asp Pro Pro Leu 
            100                 105                 110         


Val Asp Ala Ala Val Phe Val Thr Arg Thr Asp Phe Cys Val His Lys 
        115                 120                 125             


Asp Glu Pro Cys Asp Thr Val Gly Ile Ala Tyr Leu Gly Gly Val Cys 
    130                 135                 140                 


Ser Ala Lys Arg Lys Cys Val Leu Ala Glu Asp Asn Gly Leu Asn Leu 
145                 150                 155                 160 


Ala Phe Thr Ile Ala His Glu Leu Gly His Asn Leu Gly Met Asn His 
                165                 170                 175     


Asp Asp Asp His Ser Ser Cys Ala Gly Arg Ser His Ile Met Ser Gly 
            180                 185                 190         


Glu Trp Val Lys Gly Arg Asn Pro Ser Asp Leu Ser Trp Ser Ser Cys 
        195                 200                 205             


Ser Arg Asp Asp Leu Glu Asn Phe Leu Lys Ser Lys Val Ser Thr Cys 
    210                 215                 220                 


Leu Leu Val Thr Asp Pro Arg Ser Gln His Thr Val Arg Leu Pro His 
225                 230                 235                 240 


Lys Leu Pro Gly Met His Tyr Ser Ala Asn Glu Gln Cys Gln Ile Leu 
                245                 250                 255     


Phe Gly Met Asn Ala Thr Phe Cys Arg Asn Met Glu His Leu Met Cys 
            260                 265                 270         


Ala Gly Leu Trp Cys Leu Val Glu Gly Asp Thr Ser Cys Lys Thr Lys 
        275                 280                 285             


Leu Asp Pro Pro Leu Asp Gly Thr Glu Cys Gly Ala Asp Lys Trp Cys 
    290                 295                 300                 


Arg Ala Gly Glu Cys Val Ser Lys Thr Pro Ile Pro Glu His Val Asp 
305                 310                 315                 320 


Gly Asp Trp Ser Pro Trp Gly Ala Trp Ser Met Cys Ser Arg Thr Cys 
                325                 330                 335     


Gly Thr Gly Ala Arg Phe Arg Gln Arg Lys Cys Asp Asn Pro Pro Pro 
            340                 345                 350         


Gly Pro Gly Gly Thr His Cys Pro Gly Ala Ser Val Glu His Ala Val 
        355                 360                 365             


Cys Glu Asn Leu Pro Cys Pro Lys Gly Leu Pro Ser Phe Arg Asp Gln 
    370                 375                 380                 


Gln Cys Gln Ala His Asp Arg Leu Ser Pro Lys Lys Lys Gly Leu Leu 
385                 390                 395                 400 


Thr Ala Val Val Val Asp Asp Lys Pro Cys Glu Leu Tyr Cys Ser Pro 
                405                 410                 415     


Leu Gly Lys Glu Ser Pro Leu Leu Val Ala Asp Arg Val Leu Asp Gly 
            420                 425                 430         


Thr Pro Cys Gly Pro Tyr Glu Thr Asp Leu Cys Val His Gly Lys Cys 
        435                 440                 445             


Gln Lys Ile Gly Cys Asp Gly Ile Ile Gly Ser Ala Ala Lys Glu Asp 
    450                 455                 460                 


Arg Cys Gly Val Cys Ser Gly Asp Gly Lys Thr Cys His Leu Val Lys 
465                 470                 475                 480 


Gly Asp Phe Ser His Ala Arg Gly Thr Ala Leu Lys Asp Ser Gly Lys 
                485                 490                 495     


Gly Ser Ile Asn Ser Asp Trp Lys Ile Glu Leu Pro Gly Glu Phe Gln 
            500                 505                 510         


Ile Ala Gly Thr Thr Val Arg Tyr Val Arg Arg Gly Leu Trp Glu Lys 
        515                 520                 525             


Ile Ser Ala Lys Gly Pro Thr Lys Leu Pro Leu His Leu Met Val Leu 
    530                 535                 540                 


Leu Phe His Asp Gln Asp Tyr Gly Ile His Tyr Glu Tyr Thr Val Pro 
545                 550                 555                 560 


Val Asn Arg Thr Ala Glu Asn Gln Ser Glu Pro Glu Lys Pro Gln Asp 
                565                 570                 575     


Ser Leu Phe Ile Trp Thr His Ser Gly Trp Glu Gly Cys Ser Val Gln 
            580                 585                 590         


Cys Gly Gly Gly Glu Arg Arg Thr Ile Val Ser Cys Thr Arg Ile Val 
        595                 600                 605             


Asn Lys Thr Thr Thr Leu Val Asn Asp Ser Asp Cys Pro Gln Ala Ser 
    610                 615                 620                 


Arg Pro Glu Pro Gln Val Arg Arg Cys Asn Leu His Pro Cys Gln Ser 
625                 630                 635                 640 


Arg Trp Val Ala Gly Pro Trp Ser Pro Cys Ser Ala Thr Cys Glu Lys 
                645                 650                 655     


Gly Phe Gln His Arg Glu Val Thr Cys Val Tyr Gln Leu Gln Asn Gly 
            660                 665                 670         


Thr His Val Ala Thr Arg Pro Leu Tyr Cys Pro Gly Pro Arg Pro Ala 
        675                 680                 685             


Ala Val Gln Ser Cys Glu Gly Gln Asp Cys Leu Ser Ile Trp Glu Ala 
    690                 695                 700                 


Ser Glu Trp Ser Gln Cys Ser Ala Ser Cys Gly Lys Gly Val Trp Lys 
705                 710                 715                 720 


Arg Thr Val Ala Cys Thr Asn Ser Gln Gly Lys Cys Asp Ala Ser Thr 
                725                 730                 735     


Arg Pro Arg Ala Glu Glu Ala Cys Glu Asp Tyr Ser Gly Cys Tyr Glu 
            740                 745                 750         


Trp Lys Thr Gly Asp Trp Ser Thr Cys Ser Ser Thr Cys Gly Lys Gly 
        755                 760                 765             


Leu Gln Ser Arg Val Val Gln Cys Met His Lys Val Thr Gly Arg His 
    770                 775                 780                 


Gly Ser Glu Cys Pro Ala Leu Ser Lys Pro Ala Pro Tyr Arg Gln Cys 
785                 790                 795                 800 


Tyr Gln Glu Val Cys Asn Asp Arg Ile Asn Ala Asn Thr Ile Thr Ser 
                805                 810                 815     


Pro Arg Leu Ala Ala Leu Thr Tyr Lys Cys Thr Arg Asp Gln Trp Thr 
            820                 825                 830         


Val Tyr Cys Arg Val Ile Arg Glu Lys Asn Leu Cys Gln Asp Met Arg 
        835                 840                 845             


Trp Tyr Gln Arg Cys Cys Gln Thr Cys Arg Asp Phe Tyr Ala Asn Lys 
    850                 855                 860                 


Met Arg Gln Pro Pro Pro Asn Ser 
865                 870         


<210>  2716
<211>  945
<212>  PRT
<213>  Homo Sapiens

<400>  2716

Ser Leu Leu Arg Ser His Arg Asn Glu Glu Leu Asn Val Glu Thr Leu 
1               5                   10                  15      


Val Val Val Asp Lys Lys Met Met Gln Asn His Gly His Glu Asn Ile 
            20                  25                  30          


Thr Thr Tyr Val Leu Thr Ile Leu Asn Met Val Ser Ala Leu Phe Lys 
        35                  40                  45              


Asp Gly Thr Ile Gly Gly Asn Ile Asn Ile Ala Ile Val Gly Leu Ile 
    50                  55                  60                  


Leu Leu Glu Asp Glu Gln Pro Gly Leu Val Ile Ser His His Ala Asp 
65                  70                  75                  80  


His Thr Leu Ser Ser Phe Cys Gln Trp Gln Ser Gly Leu Met Gly Lys 
                85                  90                  95      


Asp Gly Thr Arg His Asp His Ala Ile Leu Leu Thr Gly Leu Asp Ile 
            100                 105                 110         


Cys Ser Trp Lys Asn Glu Pro Cys Asp Thr Leu Gly Phe Ala Pro Ile 
        115                 120                 125             


Ser Gly Met Cys Ser Lys Tyr Arg Ser Cys Thr Ile Asn Glu Asp Thr 
    130                 135                 140                 


Gly Leu Gly Leu Ala Phe Thr Ile Ala His Glu Ser Gly His Asn Phe 
145                 150                 155                 160 


Gly Met Ile His Asp Gly Glu Gly Asn Met Cys Lys Lys Ser Glu Gly 
                165                 170                 175     


Asn Ile Met Ser Pro Thr Leu Ala Gly Arg Asn Gly Val Phe Ser Trp 
            180                 185                 190         


Ser Pro Cys Ser Arg Gln Tyr Leu His Lys Phe Leu Ser Thr Ala Gln 
        195                 200                 205             


Ala Ile Cys Leu Ala Asp Gln Pro Lys Pro Val Lys Glu Tyr Lys Tyr 
    210                 215                 220                 


Pro Glu Lys Leu Pro Gly Glu Leu Tyr Asp Ala Asn Thr Gln Cys Lys 
225                 230                 235                 240 


Trp Gln Phe Gly Glu Lys Ala Lys Leu Cys Met Leu Asp Phe Lys Lys 
                245                 250                 255     


Asp Ile Cys Lys Ala Leu Trp Cys His Arg Ile Gly Arg Lys Cys Glu 
            260                 265                 270         


Thr Lys Phe Met Pro Ala Ala Glu Gly Thr Ile Cys Gly His Asp Met 
        275                 280                 285             


Trp Cys Arg Gly Gly Gln Cys Val Lys Tyr Gly Asp Glu Gly Pro Lys 
    290                 295                 300                 


Pro Thr His Gly His Trp Ser Asp Trp Ser Ser Trp Ser Pro Cys Ser 
305                 310                 315                 320 


Arg Thr Cys Gly Gly Gly Val Ser His Arg Ser Arg Leu Cys Thr Asn 
                325                 330                 335     


Pro Lys Pro Ser His Gly Gly Lys Phe Cys Glu Gly Ser Thr Arg Thr 
            340                 345                 350         


Leu Lys Leu Cys Asn Ser Gln Lys Cys Pro Arg Asp Ser Val Asp Phe 
        355                 360                 365             


Arg Ala Ala Gln Cys Ala Glu His Asn Ser Arg Arg Phe Arg Gly Arg 
    370                 375                 380                 


His Tyr Lys Trp Lys Pro Tyr Thr Gln Val Glu Asp Gln Asp Leu Cys 
385                 390                 395                 400 


Lys Leu Tyr Cys Ile Ala Glu Gly Phe Asp Phe Phe Phe Ser Leu Ser 
                405                 410                 415     


Asn Lys Val Lys Asp Gly Thr Pro Cys Ser Glu Asp Ser Arg Asn Val 
            420                 425                 430         


Cys Ile Asp Gly Ile Cys Glu Arg Val Gly Cys Asp Asn Val Leu Gly 
        435                 440                 445             


Ser Asp Ala Val Glu Asp Val Cys Gly Val Cys Asn Gly Asn Asn Ser 
    450                 455                 460                 


Ala Cys Thr Ile His Arg Gly Leu Tyr Thr Lys His His His Thr Asn 
465                 470                 475                 480 


Gln Tyr Tyr His Met Val Thr Ile Pro Ser Gly Ala Arg Ser Ile Arg 
                485                 490                 495     


Ile Tyr Glu Met Asn Val Ser Thr Ser Tyr Ile Ser Val Arg Asn Ala 
            500                 505                 510         


Leu Arg Arg Tyr Tyr Leu Asn Gly His Trp Thr Val Asp Trp Pro Gly 
        515                 520                 525             


Arg Tyr Lys Phe Ser Gly Thr Thr Phe Asp Tyr Arg Arg Ser Tyr Asn 
    530                 535                 540                 


Glu Pro Glu Asn Leu Ile Ala Thr Gly Pro Thr Asn Glu Thr Leu Ile 
545                 550                 555                 560 


Val Glu Leu Leu Phe Gln Gly Arg Asn Pro Gly Val Ala Trp Glu Tyr 
                565                 570                 575     


Ser Met Pro Arg Leu Gly Thr Glu Lys Gln Pro Pro Ala Gln Pro Ser 
            580                 585                 590         


Tyr Thr Trp Ala Ile Val Arg Ser Glu Cys Ser Val Ser Cys Gly Gly 
        595                 600                 605             


Gly Gln Met Thr Val Arg Glu Gly Cys Tyr Arg Asp Leu Lys Phe Gln 
    610                 615                 620                 


Val Asn Met Ser Phe Cys Asn Pro Lys Thr Arg Pro Val Thr Gly Leu 
625                 630                 635                 640 


Val Pro Cys Lys Val Ser Ala Cys Pro Pro Ser Trp Ser Val Gly Asn 
                645                 650                 655     


Trp Ser Ala Cys Ser Arg Thr Cys Gly Gly Gly Ala Gln Ser Arg Pro 
            660                 665                 670         


Val Gln Cys Thr Arg Arg Val His Tyr Asp Ser Glu Pro Val Pro Ala 
        675                 680                 685             


Ser Leu Cys Pro Gln Pro Ala Pro Ser Ser Arg Gln Ala Cys Asn Ser 
    690                 695                 700                 


Gln Ser Cys Pro Pro Ala Trp Ser Ala Gly Pro Trp Ala Glu Cys Ser 
705                 710                 715                 720 


His Thr Cys Gly Lys Gly Trp Arg Lys Arg Ala Val Ala Cys Lys Ser 
                725                 730                 735     


Thr Asn Pro Ser Ala Arg Ala Gln Leu Leu Pro Asp Ala Val Cys Thr 
            740                 745                 750         


Ser Glu Pro Lys Pro Arg Met His Glu Ala Cys Leu Leu Gln Arg Cys 
        755                 760                 765             


His Lys Pro Lys Lys Leu Gln Trp Leu Val Ser Ala Trp Ser Gln Cys 
    770                 775                 780                 


Ser Val Thr Cys Glu Arg Gly Thr Gln Lys Arg Phe Leu Lys Cys Ala 
785                 790                 795                 800 


Glu Lys Tyr Val Ser Gly Lys Tyr Arg Glu Leu Ala Ser Lys Lys Cys 
                805                 810                 815     


Ser His Leu Pro Lys Pro Ser Leu Glu Leu Glu Arg Ala Cys Ala Pro 
            820                 825                 830         


Leu Pro Cys Pro Arg His Pro Pro Phe Ala Ala Ala Gly Pro Ser Arg 
        835                 840                 845             


Gly Ser Trp Phe Ala Ser Pro Trp Ser Gln Cys Thr Ala Ser Cys Gly 
    850                 855                 860                 


Gly Gly Val Gln Thr Arg Ser Val Gln Cys Leu Ala Gly Gly Arg Pro 
865                 870                 875                 880 


Ala Ser Gly Cys Leu Leu His Gln Lys Pro Ser Ala Ser Leu Ala Cys 
                885                 890                 895     


Asn Thr His Phe Cys Pro Ile Ala Glu Lys Lys Asp Ala Phe Cys Lys 
            900                 905                 910         


Asp Tyr Phe His Trp Cys Tyr Leu Val Pro Gln His Gly Met Cys Ser 
        915                 920                 925             


His Lys Phe Tyr Gly Lys Gln Cys Cys Lys Thr Cys Ser Lys Ser Asn 
    930                 935                 940                 


Leu 
945 


<210>  2717
<211>  738
<212>  PRT
<213>  Homo Sapiens

<400>  2717

Phe Val Ser Ile Pro Arg Tyr Val Glu Thr Leu Val Val Ala Asp Glu 
1               5                   10                  15      


Ser Met Val Lys Phe His Gly Ala Asp Leu Glu His Tyr Leu Leu Thr 
            20                  25                  30          


Leu Leu Ala Thr Ala Ala Arg Leu Tyr Arg His Pro Ser Ile Leu Asn 
        35                  40                  45              


Pro Ile Asn Ile Val Val Val Lys Val Leu Leu Leu Arg Asp Arg Asp 
    50                  55                  60                  


Ser Gly Pro Lys Val Thr Gly Asn Ala Ala Leu Thr Leu Arg Asn Phe 
65                  70                  75                  80  


Cys Ala Trp Gln Lys Lys Leu Asn Lys Val Ser Asp Lys His Pro Glu 
                85                  90                  95      


Tyr Trp Asp Thr Ala Ile Leu Phe Thr Arg Gln Asp Leu Cys Gly Ala 
            100                 105                 110         


Thr Thr Cys Asp Thr Leu Gly Met Ala Asp Val Gly Thr Met Cys Asp 
        115                 120                 125             


Pro Lys Arg Ser Cys Ser Val Ile Glu Asp Asp Gly Leu Pro Ser Ala 
    130                 135                 140                 


Phe Thr Thr Ala His Glu Leu Gly His Val Phe Asn Met Pro His Asp 
145                 150                 155                 160 


Asn Val Lys Val Cys Glu Glu Val Phe Gly Lys Leu Arg Ala Asn His 
                165                 170                 175     


Met Met Ser Pro Thr Leu Ile Gln Ile Asp Arg Ala Asn Pro Trp Ser 
            180                 185                 190         


Ala Cys Ser Ala Ala Ile Ile Thr Asp Phe Leu Asp Ser Gly His Gly 
        195                 200                 205             


Asp Cys Leu Leu Asp Gln Pro Ser Lys Pro Ile Ser Leu Pro Glu Asp 
    210                 215                 220                 


Leu Pro Gly Ala Ser Tyr Thr Leu Ser Gln Gln Cys Glu Leu Ala Phe 
225                 230                 235                 240 


Gly Val Gly Ser Lys Pro Cys Pro Tyr Met Gln Tyr Cys Thr Lys Leu 
                245                 250                 255     


Trp Cys Thr Gly Lys Ala Lys Gly Gln Met Val Cys Gln Thr Arg His 
            260                 265                 270         


Phe Pro Trp Ala Asp Gly Thr Ser Cys Gly Glu Gly Lys Leu Cys Leu 
        275                 280                 285             


Lys Gly Ala Cys Val Glu Arg His Asn Leu Asn Lys His Arg Val Asp 
    290                 295                 300                 


Gly Ser Trp Ala Lys Trp Asp Pro Tyr Gly Pro Cys Ser Arg Thr Cys 
305                 310                 315                 320 


Gly Gly Gly Val Gln Leu Ala Arg Arg Gln Cys Thr Asn Pro Thr Pro 
                325                 330                 335     


Ala Asn Gly Gly Lys Tyr Cys Glu Gly Val Arg Val Lys Tyr Arg Ser 
            340                 345                 350         


Cys Asn Leu Glu Pro Cys Pro Ser Ser Ala Ser Gly Lys Ser Phe Arg 
        355                 360                 365             


Glu Glu Gln Cys Glu Ala Phe Asn Gly Tyr Asn His Ser Thr Asn Arg 
    370                 375                 380                 


Leu Thr Leu Ala Val Ala Trp Val Pro Lys Tyr Ser Gly Val Ser Pro 
385                 390                 395                 400 


Arg Asp Lys Cys Lys Leu Ile Cys Arg Ala Asn Gly Thr Gly Tyr Phe 
                405                 410                 415     


Tyr Val Leu Ala Pro Lys Val Val Asp Gly Thr Leu Cys Ser Pro Asp 
            420                 425                 430         


Ser Thr Ser Val Cys Val Gln Gly Lys Cys Ile Lys Ala Gly Cys Asp 
        435                 440                 445             


Gly Asn Leu Gly Ser Lys Lys Arg Phe Asp Lys Cys Gly Val Cys Gly 
    450                 455                 460                 


Gly Asp Asn Lys Ser Cys Lys Lys Val Thr Gly Leu Phe Thr Lys Pro 
465                 470                 475                 480 


Met His Gly Tyr Asn Phe Val Val Ala Ile Pro Ala Gly Ala Ser Ser 
                485                 490                 495     


Ile Asp Ile Arg Gln Arg Gly Tyr Lys Gly Leu Ile Gly Asp Asp Asn 
            500                 505                 510         


Tyr Leu Ala Leu Lys Asn Ser Gln Gly Lys Tyr Leu Leu Asn Gly His 
        515                 520                 525             


Phe Val Val Ser Ala Val Glu Arg Asp Leu Val Val Lys Gly Ser Leu 
    530                 535                 540                 


Leu Arg Tyr Ser Gly Thr Gly Thr Ala Val Glu Ser Leu Gln Ala Ser 
545                 550                 555                 560 


Arg Pro Ile Leu Glu Pro Leu Thr Val Glu Val Leu Ser Val Gly Lys 
                565                 570                 575     


Met Thr Pro Pro Arg Val Arg Tyr Ser Phe Tyr Leu Pro Lys Glu Pro 
            580                 585                 590         


Arg Glu Asp Lys Ser Ser His Pro Lys Asp Pro Arg Gly Pro Ser Val 
        595                 600                 605             


Leu His Asn Ser Val Leu Ser Leu Ser Asn Gln Val Glu Gln Pro Asp 
    610                 615                 620                 


Asp Arg Pro Pro Ala Arg Trp Val Ala Gly Ser Trp Gly Pro Cys Ser 
625                 630                 635                 640 


Ala Ser Cys Gly Ser Gly Leu Gln Lys Arg Ala Val Asp Cys Arg Gly 
                645                 650                 655     


Ser Ala Gly Gln Arg Thr Val Pro Ala Cys Asp Ala Ala His Arg Pro 
            660                 665                 670         


Val Glu Thr Gln Ala Cys Gly Glu Pro Cys Pro Thr Trp Glu Leu Ser 
        675                 680                 685             


Ala Trp Ser Pro Cys Ser Lys Ser Cys Gly Arg Gly Phe Gln Arg Arg 
    690                 695                 700                 


Ser Leu Lys Cys Val Gly His Gly Gly Arg Leu Leu Ala Arg Asp Gln 
705                 710                 715                 720 


Cys Asn Leu His Arg Lys Pro Gln Glu Leu Asp Phe Cys Val Leu Arg 
                725                 730                 735     


Pro Cys 
        


<210>  2718
<211>  937
<212>  PRT
<213>  Homo Sapiens

<400>  2718

Ser Ala Gly Lys Ser Gln Lys Gly Leu Asn Val Glu Thr Leu Val Val 
1               5                   10                  15      


Ala Asp Lys Lys Met Val Glu Lys His Gly Lys Gly Asn Val Thr Thr 
            20                  25                  30          


Tyr Ile Leu Thr Val Met Asn Met Val Ser Gly Leu Phe Lys Asp Gly 
        35                  40                  45              


Thr Ile Gly Ser Asp Ile Asn Val Val Val Val Ser Leu Ile Leu Leu 
    50                  55                  60                  


Glu Gln Glu Pro Gly Gly Leu Leu Ile Asn His His Ala Asp Gln Ser 
65                  70                  75                  80  


Leu Asn Ser Phe Cys Gln Trp Gln Ser Ala Leu Ile Gly Lys Asn Gly 
                85                  90                  95      


Lys Arg His Asp His Ala Ile Leu Leu Thr Gly Phe Asp Ile Cys Ser 
            100                 105                 110         


Trp Lys Asn Glu Pro Cys Asp Thr Leu Gly Phe Ala Pro Ile Ser Gly 
        115                 120                 125             


Met Cys Ser Lys Tyr Arg Ser Cys Thr Ile Asn Glu Asp Thr Gly Leu 
    130                 135                 140                 


Gly Leu Ala Phe Thr Ile Ala His Glu Ser Gly His Asn Phe Gly Met 
145                 150                 155                 160 


Ile His Asp Gly Glu Gly Asn Pro Cys Arg Lys Ala Glu Gly Asn Ile 
                165                 170                 175     


Met Ser Pro Thr Leu Thr Gly Asn Asn Gly Val Phe Ser Trp Ser Ser 
            180                 185                 190         


Cys Ser Arg Gln Tyr Leu Lys Lys Phe Leu Ser Thr Pro Gln Ala Gly 
        195                 200                 205             


Cys Leu Val Asp Glu Pro Lys Gln Ala Gly Gln Tyr Lys Tyr Pro Asp 
    210                 215                 220                 


Lys Leu Pro Gly Gln Ile Tyr Asp Ala Asp Thr Gln Cys Lys Trp Gln 
225                 230                 235                 240 


Phe Gly Ala Lys Ala Lys Leu Cys Ser Leu Gly Phe Val Lys Asp Ile 
                245                 250                 255     


Cys Lys Ser Leu Trp Cys His Arg Val Gly His Arg Cys Glu Thr Lys 
            260                 265                 270         


Phe Met Pro Ala Ala Glu Gly Thr Val Cys Gly Leu Ser Met Trp Cys 
        275                 280                 285             


Arg Gln Gly Gln Cys Val Lys Phe Gly Glu Leu Gly Pro Arg Pro Ile 
    290                 295                 300                 


His Gly Gln Trp Ser Ala Trp Ser Lys Trp Ser Glu Cys Ser Arg Thr 
305                 310                 315                 320 


Cys Gly Gly Gly Val Lys Phe Gln Glu Arg His Cys Asn Asn Pro Lys 
                325                 330                 335     


Pro Gln Tyr Gly Gly Ile Phe Cys Pro Gly Ser Ser Arg Ile Tyr Gln 
            340                 345                 350         


Leu Cys Asn Ile Asn Pro Cys Asn Glu Asn Ser Leu Asp Phe Arg Ala 
        355                 360                 365             


Gln Gln Cys Ala Glu Tyr Asn Ser Lys Pro Phe Arg Gly Trp Phe Tyr 
    370                 375                 380                 


Gln Trp Lys Pro Tyr Thr Lys Val Glu Glu Glu Asp Arg Cys Lys Leu 
385                 390                 395                 400 


Tyr Cys Lys Ala Glu Asn Phe Glu Phe Phe Phe Ala Met Ser Gly Lys 
                405                 410                 415     


Val Lys Asp Gly Thr Pro Cys Ser Pro Asn Lys Asn Asp Val Cys Ile 
            420                 425                 430         


Asp Gly Val Cys Glu Leu Val Gly Cys Asp His Glu Leu Gly Ser Lys 
        435                 440                 445             


Ala Val Ser Asp Ala Cys Gly Val Cys Lys Gly Asp Asn Ser Thr Cys 
    450                 455                 460                 


Lys Phe Tyr Lys Gly Leu Tyr Leu Asn Gln His Lys Ala Asn Glu Tyr 
465                 470                 475                 480 


Tyr Pro Val Val Ile Ile Pro Ala Gly Ala Arg Ser Ile Glu Ile Gln 
                485                 490                 495     


Glu Leu Gln Val Ser Ser Ser Tyr Leu Ala Val Arg Ser Leu Ser Gln 
            500                 505                 510         


Lys Tyr Tyr Leu Thr Gly Gly Trp Ser Ile Asp Trp Pro Gly Glu Phe 
        515                 520                 525             


Pro Phe Ala Gly Thr Thr Phe Glu Tyr Gln Arg Ser Phe Asn Arg Pro 
    530                 535                 540                 


Glu Arg Leu Tyr Ala Pro Gly Pro Thr Asn Glu Thr Leu Val Phe Glu 
545                 550                 555                 560 


Ile Leu Met Gln Gly Lys Asn Pro Gly Ile Ala Trp Lys Tyr Ala Leu 
                565                 570                 575     


Pro Lys Val Met Asn Gly Thr Pro Pro Ala Thr Lys Arg Pro Ala Tyr 
            580                 585                 590         


Thr Trp Ser Ile Val Gln Ser Glu Cys Ser Val Ser Cys Gly Gly Gly 
        595                 600                 605             


Tyr Ile Asn Val Lys Ala Ile Cys Leu Arg Asp Gln Asn Thr Gln Val 
    610                 615                 620                 


Asn Ser Ser Phe Cys Ser Ala Lys Thr Lys Pro Val Thr Glu Pro Lys 
625                 630                 635                 640 


Ile Cys Asn Ala Phe Ser Cys Pro Ala Tyr Trp Met Pro Gly Glu Trp 
                645                 650                 655     


Ser Thr Cys Ser Lys Ala Cys Ala Gly Gly Gln Gln Ser Arg Lys Ile 
            660                 665                 670         


Gln Cys Val Gln Lys Lys Pro Phe Gln Lys Glu Glu Ala Val Leu His 
        675                 680                 685             


Ser Leu Cys Pro Val Ser Thr Pro Thr Gln Val Gln Ala Cys Asn Ser 
    690                 695                 700                 


His Ala Cys Pro Pro Gln Trp Ser Leu Gly Pro Trp Ser Gln Cys Ser 
705                 710                 715                 720 


Lys Thr Cys Gly Arg Gly Val Arg Lys Arg Glu Leu Leu Cys Lys Gly 
                725                 730                 735     


Ser Ala Ala Glu Thr Leu Pro Glu Ser Gln Cys Thr Ser Leu Pro Arg 
            740                 745                 750         


Pro Glu Leu Gln Glu Gly Cys Val Leu Gly Arg Cys Pro Lys Asn Ser 
        755                 760                 765             


Arg Leu Gln Trp Val Ala Ser Ser Trp Ser Glu Cys Ser Ala Thr Cys 
    770                 775                 780                 


Gly Leu Gly Val Arg Lys Arg Glu Met Lys Cys Ser Glu Lys Gly Phe 
785                 790                 795                 800 


Gln Gly Lys Leu Ile Thr Phe Pro Glu Arg Arg Cys Arg Asn Ile Lys 
                805                 810                 815     


Lys Pro Asn Leu Asp Leu Glu Glu Thr Cys Asn Arg Arg Ala Cys Pro 
            820                 825                 830         


Ala His Pro Val Tyr Asn Met Val Ala Gly Trp Tyr Ser Leu Pro Trp 
        835                 840                 845             


Gln Gln Cys Thr Val Thr Cys Gly Gly Gly Val Gln Thr Arg Ser Val 
    850                 855                 860                 


His Cys Val Gln Gln Gly Arg Pro Ser Ser Ser Cys Leu Leu His Gln 
865                 870                 875                 880 


Lys Pro Pro Val Leu Arg Ala Cys Asn Thr Asn Phe Cys Pro Ala Pro 
                885                 890                 895     


Glu Lys Arg Glu Asp Pro Ser Cys Val Asp Phe Phe Asn Trp Cys His 
            900                 905                 910         


Leu Val Pro Gln His Gly Val Cys Asn His Lys Phe Tyr Gly Lys Gln 
        915                 920                 925             


Cys Cys Lys Ser Cys Thr Arg Lys Ile 
    930                 935         


<210>  2719
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  2719

Ala Glu Ala Val Trp Thr Ala Tyr Leu Asn Val Ser Trp Arg Val Pro 
1               5                   10                  15      


His Thr Gly Val Asn Arg Thr Val Trp Glu Leu Ser Glu Glu Gly Val 
            20                  25                  30          


Tyr Gly Gln Asp Ser Pro Leu Glu Pro Val Ala Gly Val Leu Val Pro 
        35                  40                  45              


Pro Asp Gly Pro Gly Ala Leu Asn Ala Cys Asn Pro His Thr Asn Phe 
    50                  55                  60                  


Thr Val Pro Thr Val Trp Gly Ser Thr Val Gln Val Ser Trp Leu Ala 
65                  70                  75                  80  


Leu Ile Gln Arg Gly Gly Gly Cys Thr Phe Ala Asp Lys Ile His Leu 
                85                  90                  95      


Ala Tyr Glu Arg Gly Ala Ser Gly Ala Val Ile Phe Asn Phe Pro Gly 
            100                 105                 110         


Thr Arg Asn Glu Val Ile Pro Met Ser His Pro Gly Ala Val Asp Ile 
        115                 120                 125             


Val Ala Ile Met Ile Gly Asn Leu Lys Gly Thr Lys Ile Leu Gln Ser 
    130                 135                 140                 


Ile Gln Arg Gly Ile Gln Val Thr Met Val Ile Glu Val Gly Lys Lys 
145                 150                 155                 160 


His Gly Pro Trp Val Asn His Tyr Ser 
                165                 


<210>  2720
<211>  64
<212>  PRT
<213>  Homo Sapiens

<400>  2720

Leu Asn Pro Gln Lys Pro Leu Tyr Ser Ser Cys Leu Ser Val Glu Lys 
1               5                   10                  15      


Cys Tyr Gln Gln Lys Asp Trp Gln Arg Leu Leu Leu Ser Pro Leu His 
            20                  25                  30          


His Ala Asp Asp Trp His Leu Tyr Phe Asn Met Ala Ser Met Leu Trp 
        35                  40                  45              


Lys Gly Ile Asn Leu Glu Arg Arg Leu Gly Ser Arg Trp Phe Ala Tyr 
    50                  55                  60                  


<210>  2721
<211>  283
<212>  PRT
<213>  Homo Sapiens

<400>  2721

Ser Ser Pro Cys Ile Met Glu Lys Lys Asp Leu Gly Pro Lys Pro Ala 
1               5                   10                  15      


Leu Ile Gly His Arg Gly Ala Pro Met Leu Ala Pro Glu His Thr Leu 
            20                  25                  30          


Met Ser Phe Arg Lys Ala Leu Glu Gln Lys Leu Tyr Gly Leu Gln Ala 
        35                  40                  45              


Asp Ile Thr Ile Ser Leu Asp Gly Val Pro Phe Leu Met His Asp Thr 
    50                  55                  60                  


Thr Leu Arg Arg Thr Thr Asn Val Glu Glu Glu Phe Pro Glu Leu Ala 
65                  70                  75                  80  


Arg Arg Pro Ala Ser Met Leu Asn Trp Thr Thr Leu Gln Arg Leu Asn 
                85                  90                  95      


Ala Gly Gln Trp Phe Leu Lys Thr Val Pro Phe Trp Thr Ala Ser Ser 
            100                 105                 110         


Leu Ser Pro Ser Asp His Arg Glu Ala Gln Asn Gln Ser Ile Cys Ser 
        115                 120                 125             


Leu Ala Glu Leu Leu Glu Leu Ala Lys Gly Asn Ala Thr Leu Leu Leu 
    130                 135                 140                 


Asn Leu Arg Asp Pro Pro Arg Glu His Pro Tyr Arg Ser Ser Phe Ile 
145                 150                 155                 160 


Asn Val Thr Leu Glu Ala Val Leu His Ser Gly Phe Pro Gln His Gln 
                165                 170                 175     


Val Met Trp Leu Pro Ser Arg Gln Arg Pro Leu Val Arg Lys Val Ala 
            180                 185                 190         


Pro Gly Phe Gln Gln Thr Ser Gly Ser Lys Glu Ala Val Ala Ser Leu 
        195                 200                 205             


Arg Arg Gly His Ile Gln Arg Leu Asn Leu Arg Tyr Thr Gln Val Ser 
    210                 215                 220                 


Arg Gln Glu Leu Arg Asp Tyr Ala Ser Trp Asn Leu Ser Val Asn Leu 
225                 230                 235                 240 


Tyr Thr Val Asn Ala Pro Trp Leu Phe Ser Leu Leu Trp Cys Ala Gly 
                245                 250                 255     


Val Pro Ser Val Thr Ser Asp Asn Ser His Thr Leu Ser Gln Val Pro 
            260                 265                 270         


Ser Pro Leu Trp Ile Met Pro Pro Asp Glu Tyr 
        275                 280             


<210>  2722
<211>  411
<212>  PRT
<213>  Homo Sapiens

<400>  2722

Pro Ser Leu Ile Lys Gln Gln Val Leu Lys Asn Val Arg Ile Asp Pro 
1               5                   10                  15      


Ser Ser Leu Ser Phe Asn Met Trp Lys Glu Ile Pro Ile Pro Phe Tyr 
            20                  25                  30          


Leu Ser Val Tyr Phe Phe Asp Val Met Asn Pro Ser Glu Ile Leu Lys 
        35                  40                  45              


Gly Glu Lys Pro Gln Val Arg Glu Arg Gly Pro Tyr Val Tyr Arg Glu 
    50                  55                  60                  


Phe Arg His Lys Ser Asn Ile Thr Phe Asn Asn Asn Asp Thr Val Ser 
65                  70                  75                  80  


Phe Leu Glu Tyr Arg Thr Phe Gln Phe Gln Pro Ser Lys Ser His Gly 
                85                  90                  95      


Ser Glu Ser Asp Tyr Ile Val Met Pro Asn Ile Leu Val Leu Gly Ala 
            100                 105                 110         


Ala Val Met Met Glu Asn Lys Pro Met Thr Leu Lys Leu Ile Met Thr 
        115                 120                 125             


Leu Ala Phe Thr Thr Leu Gly Glu Arg Ala Phe Met Asn Arg Thr Val 
    130                 135                 140                 


Gly Glu Ile Met Trp Gly Tyr Lys Asp Pro Leu Val Asn Leu Ile Asn 
145                 150                 155                 160 


Lys Tyr Phe Pro Gly Met Phe Pro Phe Lys Asp Lys Phe Gly Leu Phe 
                165                 170                 175     


Ala Glu Leu Asn Asn Ser Asp Ser Gly Leu Phe Thr Val Phe Thr Gly 
            180                 185                 190         


Val Gln Asn Ile Ser Arg Ile His Leu Val Asp Lys Trp Asn Gly Leu 
        195                 200                 205             


Ser Lys Val Asp Phe Trp His Ser Asp Gln Cys Asn Met Ile Asn Gly 
    210                 215                 220                 


Thr Ser Gly Gln Met Trp Pro Pro Phe Met Thr Pro Glu Ser Ser Leu 
225                 230                 235                 240 


Glu Phe Tyr Ser Pro Glu Ala Cys Arg Ser Met Lys Leu Met Tyr Lys 
                245                 250                 255     


Glu Ser Gly Val Phe Glu Gly Ile Pro Thr Tyr Arg Phe Val Ala Pro 
            260                 265                 270         


Lys Thr Leu Phe Ala Asn Gly Ser Ile Tyr Pro Pro Asn Glu Gly Phe 
        275                 280                 285             


Cys Pro Cys Leu Glu Ser Gly Ile Gln Asn Val Ser Thr Cys Arg Phe 
    290                 295                 300                 


Ser Ala Pro Leu Phe Leu Ser His Pro His Phe Leu Asn Ala Asp Pro 
305                 310                 315                 320 


Val Leu Ala Glu Ala Val Thr Gly Leu His Pro Asn Gln Glu Ala His 
                325                 330                 335     


Ser Leu Phe Leu Asp Ile His Pro Val Thr Gly Ile Pro Met Asn Cys 
            340                 345                 350         


Ser Val Lys Leu Gln Leu Ser Leu Tyr Met Lys Ser Val Ala Gly Ile 
        355                 360                 365             


Gly Gln Thr Gly Lys Ile Glu Pro Val Val Leu Pro Leu Leu Trp Phe 
    370                 375                 380                 


Ala Glu Ser Gly Ala Met Glu Gly Glu Thr Leu His Thr Phe Tyr Thr 
385                 390                 395                 400 


Gln Leu Val Leu Met Pro Lys Val Met His Tyr 
                405                 410     


<210>  2723
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  2723

Asp Arg Ala Pro Leu Thr Ala Thr Ala Pro Gln Leu Asp Asp Glu Glu 
1               5                   10                  15      


Met Tyr Ser Ala His Met Pro Ala His Leu Arg Cys Asp Ala Cys Arg 
            20                  25                  30          


Ala Val Ala Tyr Gln Met Trp Gln Asn Leu Ala Lys Ala Glu Thr Lys 
        35                  40                  45              


Leu His Thr Ser Asn Ser Gly Gly Arg Arg Glu Leu Ser Glu Leu Val 
    50                  55                  60                  


Tyr Thr Asp Val Leu Asp Arg Ser Cys Ser Arg Asn Trp Gln Asp Tyr 
65                  70                  75                  80  


Gly Val Arg Glu Val Asp Gln Val Lys Arg Leu Thr Gly Pro Gly Leu 
                85                  90                  95      


Ser Glu Gly Pro Glu Pro Ser Ile Ser Val Met Val Thr Gly Gly Pro 
            100                 105                 110         


Trp Pro Thr Arg Leu Ser Arg Thr Cys Leu His Tyr Leu Gly Glu Phe 
        115                 120                 125             


Gly Glu Asp Gln Ile Tyr Glu Ala His Gln Gln Gly Arg Gly Ala Leu 
    130                 135                 140                 


Glu Ala Leu Leu Cys Gly Gly Pro Gln Gly Ala Cys Ser Glu Lys Val 
145                 150                 155                 160 


Ser Ala Thr Arg Glu Glu Leu 
                165         


<210>  2724
<211>  398
<212>  PRT
<213>  Homo Sapiens

<400>  2724

Gln Ile Gln Gln Gly Gly Pro Asp Glu Lys Glu Lys Thr Thr Ala Leu 
1               5                   10                  15      


Lys Asp Leu Leu Ser Arg Ile Asp Leu Asp Glu Leu Met Lys Lys Asp 
            20                  25                  30          


Glu Pro Pro Leu Asp Phe Pro Asp Thr Leu Gly Gly Phe Glu Tyr Ala 
        35                  40                  45              


Phe Asn Glu Lys Gly Gln Leu Arg His Ile Lys Thr Gly Glu Pro Phe 
    50                  55                  60                  


Val Phe Asn Tyr Arg Glu Asp Leu His Arg Trp Asn Gln Lys Arg Tyr 
65                  70                  75                  80  


Glu Ala Leu Gly Glu Ile Ile Thr Lys Tyr Val Tyr Glu Leu Leu Glu 
                85                  90                  95      


Lys Asp Cys Asn Leu Lys Lys Val Ser Ile Pro Val Asp Ala Thr Glu 
            100                 105                 110         


Ser Glu Pro Lys Ser Phe Ile Phe Met Ser Glu Asp Ala Leu Thr Asn 
        115                 120                 125             


Pro Gln Lys Leu Met Val Leu Ile His Gly Ser Gly Val Val Arg Ala 
    130                 135                 140                 


Gly Gln Trp Ala Arg Arg Leu Ile Ile Asn Glu Asp Leu Asp Ser Gly 
145                 150                 155                 160 


Thr Gln Ile Pro Phe Ile Lys Arg Ala Val Ala Glu Gly Tyr Gly Val 
                165                 170                 175     


Ile Val Leu Asn Pro Asn Glu Asn Tyr Ile Glu Val Glu Lys Pro Lys 
            180                 185                 190         


Ile His Val Gln Ser Ser Ser Asp Ser Ser Asp Glu Pro Ala Glu Lys 
        195                 200                 205             


Arg Glu Arg Lys Asp Lys Val Ser Lys Glu Thr Lys Lys Arg Arg Asp 
    210                 215                 220                 


Phe Tyr Glu Lys Tyr Arg Asn Pro Gln Arg Glu Lys Glu Met Met Gln 
225                 230                 235                 240 


Leu Tyr Ile Arg Glu Asn Gly Ser Pro Glu Glu His Ala Ile Tyr Val 
                245                 250                 255     


Trp Asp His Phe Ile Ala Gln Ala Ala Ala Glu Asn Val Phe Phe Val 
            260                 265                 270         


Ala His Ser Tyr Gly Gly Leu Ala Phe Val Glu Leu Met Ile Gln Arg 
        275                 280                 285             


Glu Ala Asp Val Lys Asn Lys Val Thr Ala Val Ala Leu Thr Asp Ser 
    290                 295                 300                 


Val His Asn Val Trp His Gln Glu Ala Gly Lys Thr Ile Arg Glu Trp 
305                 310                 315                 320 


Met Arg Glu Asn Cys Cys Asn Trp Val Ser Ser Ser Glu Pro Leu Asp 
                325                 330                 335     


Thr Ser Val Glu Ser Met Leu Pro Asp Cys Pro Arg Val Ser Ala Gly 
            340                 345                 350         


Thr Asp Arg His Glu Leu Thr Ser Trp Lys Ser Phe Pro Ser Ile Phe 
        355                 360                 365             


Lys Phe Phe Thr Glu Ala Ser Glu Ala Lys Thr Ser Ser Leu Lys Pro 
    370                 375                 380                 


Ala Val Thr Arg Arg Ser His Arg Ile Lys His Glu Asp Leu 
385                 390                 395             


<210>  2725
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  2725

Ala Arg Leu Met Gly Trp Trp Gly Pro Arg Ala Gly Phe Arg Leu Phe 
1               5                   10                  15      


Ile Pro Glu Glu Leu Ser Arg Tyr Arg Gly Gly Pro Gly Asp Pro Gly 
            20                  25                  30          


Leu Tyr Leu Ala Leu Leu Gly Arg Val Tyr Asp Val Ser Ser Gly Arg 
        35                  40                  45              


Arg His Tyr Glu Pro Gly Ser His Tyr Ser Gly Phe Ala Gly Arg Asp 
    50                  55                  60                  


Ala Ser Arg Ala Phe Val Thr Gly Asp Cys Ser Glu Ala Gly Leu Val 
65                  70                  75                  80  


Asp Asp Val Ser Asp Leu Ser Ala Ala Glu Met Leu Thr Leu His Asn 
                85                  90                  95      


Trp Leu Ser Phe Tyr Glu Lys Asn Tyr Val Cys Val Gly Arg Val Thr 
            100                 105                 110         


Gly Arg Phe Tyr Gly Glu Asp Gly Leu Pro Thr Pro Ala Leu Thr Gln 
        115                 120                 125             


Val Glu Ala Ala Ile Thr Arg Gly Leu Glu Ala Asn Lys Leu Gln Leu 
    130                 135                 140                 


Gln Glu Lys Gln Thr Phe Pro Pro Cys Asn Ala Glu Trp Ser Ser Ala 
145                 150                 155                 160 


Arg Gly Ser Arg Leu Trp Cys Ser Gln Lys Ser Gly Gly Val Ser Arg 
                165                 170                 175     


Asp Trp Ile Gly Val Pro Arg Lys Leu Tyr Lys Pro Gly Ala Lys Glu 
            180                 185                 190         


Pro Arg Cys Val Cys Val Arg Thr Thr Gly Pro Pro Ser Gly Gln Met 
        195                 200                 205             


Pro Asp Asn Pro Pro His Arg Asn Arg Gly Asp Leu Asp His Pro Asn 
    210                 215                 220                 


Leu Ala Glu Tyr Thr Gly Cys Pro Pro Leu Ala Ile Thr Cys Ser Phe 
225                 230                 235                 240 


Pro Leu 
        


<210>  2726
<211>  872
<212>  PRT
<213>  Homo Sapiens

<400>  2726

Ala Thr Phe Ile Ser Met Gln Leu Lys Lys Thr Ser Glu Val Asp Leu 
1               5                   10                  15      


Ala Lys Pro Leu Val Lys Phe Ile Gln Gln Thr Tyr Pro Ser Gly Gly 
            20                  25                  30          


Glu Glu Gln Ala Gln Tyr Cys Arg Ala Ala Glu Glu Leu Ser Lys Leu 
        35                  40                  45              


Arg Arg Ala Ala Val Gly Arg Pro Leu Asp Lys His Glu Gly Ala Leu 
    50                  55                  60                  


Glu Thr Leu Leu Arg Tyr Tyr Asp Gln Ile Cys Ser Ile Glu Pro Lys 
65                  70                  75                  80  


Phe Pro Phe Ser Glu Asn Gln Ile Cys Leu Thr Phe Thr Trp Lys Asp 
                85                  90                  95      


Ala Phe Asp Lys Gly Ser Leu Phe Gly Gly Ser Val Lys Leu Ala Leu 
            100                 105                 110         


Ala Ser Leu Gly Tyr Glu Lys Ser Cys Val Leu Phe Asn Cys Ala Ala 
        115                 120                 125             


Leu Ala Ser Gln Ile Ala Ala Glu Gln Asn Leu Asp Asn Asp Glu Gly 
    130                 135                 140                 


Leu Lys Ile Ala Ala Lys His Tyr Gln Phe Ala Ser Gly Ala Phe Leu 
145                 150                 155                 160 


His Ile Lys Glu Thr Val Leu Ser Ala Leu Ser Arg Glu Pro Thr Val 
                165                 170                 175     


Asp Ile Ser Pro Asp Thr Val Gly Thr Leu Ser Leu Ile Met Leu Ala 
            180                 185                 190         


Gln Ala Gln Glu Val Phe Phe Leu Lys Ala Thr Arg Asp Lys Met Lys 
        195                 200                 205             


Asp Ala Ile Ile Ala Lys Leu Ala Asn Gln Ala Ala Asp Tyr Phe Gly 
    210                 215                 220                 


Asp Ala Phe Lys Gln Cys Gln Tyr Lys Asp Thr Leu Pro Lys Tyr Phe 
225                 230                 235                 240 


Tyr Phe Gln Glu Val Phe Pro Val Leu Ala Ala Lys His Cys Ile Met 
                245                 250                 255     


Gln Ala Asn Ala Glu Tyr His Gln Ser Ile Leu Ala Lys Gln Gln Lys 
            260                 265                 270         


Lys Phe Gly Glu Glu Ile Ala Arg Leu Gln His Ala Ala Glu Leu Ile 
        275                 280                 285             


Lys Thr Val Ala Ser Arg Tyr Asp Glu Tyr Val Asn Val Lys Asp Phe 
    290                 295                 300                 


Ser Asp Lys Ile Asn Arg Ala Leu Ala Ala Ala Lys Lys Asp Asn Asp 
305                 310                 315                 320 


Phe Ile Tyr His Asp Arg Val Pro Asp Leu Lys Asp Leu Asp Pro Ile 
                325                 330                 335     


Gly Lys Ala Thr Leu Val Lys Ser Thr Pro Val Asn Val Pro Ile Ser 
            340                 345                 350         


Gln Lys Phe Thr Asp Leu Phe Glu Lys Met Val Pro Val Ser Val Gln 
        355                 360                 365             


Gln Ser Leu Ala Ala Tyr Asn Gln Arg Lys Ala Asp Leu Ile Asn Arg 
    370                 375                 380                 


Ser Ile Ala Gln Met Arg Glu Ala Thr Thr Leu Ala Asn Gly Val Leu 
385                 390                 395                 400 


Ala Ser Leu Asn Leu Pro Ala Ala Ile Glu Asp Val Ser Gly Asp Thr 
                405                 410                 415     


Val Pro Gln Ser Ile Leu Thr Lys Ser Arg Ser Val Ile Glu Gln Gly 
            420                 425                 430         


Gly Ile Gln Thr Val Asp Gln Leu Ile Lys Glu Leu Pro Glu Leu Leu 
        435                 440                 445             


Gln Arg Asn Arg Glu Ile Leu Asp Glu Ser Leu Arg Leu Leu Asp Glu 
    450                 455                 460                 


Glu Glu Ala Thr Asp Asn Asp Leu Arg Ala Lys Phe Lys Glu Arg Trp 
465                 470                 475                 480 


Gln Arg Thr Pro Ser Asn Glu Leu Tyr Lys Pro Leu Arg Ala Glu Gly 
                485                 490                 495     


Thr Asn Phe Arg Thr Val Leu Asp Lys Ala Val Gln Ala Asp Gly Gln 
            500                 505                 510         


Val Lys Glu Cys Tyr Gln Ser His Arg Asp Thr Ile Val Leu Leu Cys 
        515                 520                 525             


Lys Pro Glu Pro Glu Leu Asn Ala Ala Ile Pro Ser Ala Asn Pro Ala 
    530                 535                 540                 


Lys Thr Met Gln Gly Ser Glu Val Val Asn Val Leu Lys Ser Leu Leu 
545                 550                 555                 560 


Ser Asn Leu Asp Glu Val Lys Lys Glu Arg Glu Gly Leu Glu Asn Asp 
                565                 570                 575     


Leu Lys Ser Val Asn Phe Asp Met Thr Ser Lys Phe Leu Thr Ala Leu 
            580                 585                 590         


Ala Gln Asp Gly Val Ile Asn Glu Glu Ala Leu Ser Val Thr Glu Leu 
        595                 600                 605             


Asp Arg Val Tyr Gly Gly Leu Thr Thr Lys Val Gln Glu Ser Leu Lys 
    610                 615                 620                 


Lys Gln Glu Gly Leu Leu Lys Asn Ile Gln Val Ser His Gln Glu Phe 
625                 630                 635                 640 


Ser Lys Met Lys Gln Ser Asn Asn Glu Ala Asn Leu Arg Glu Glu Val 
                645                 650                 655     


Leu Lys Asn Leu Ala Thr Ala Tyr Asp Asn Phe Val Glu Leu Val Ala 
            660                 665                 670         


Asn Leu Lys Glu Gly Thr Lys Phe Tyr Asn Glu Leu Thr Glu Ile Leu 
        675                 680                 685             


Val Arg Phe Gln Asn Lys Cys Ser Asp Ile Val Phe Ala Arg Lys Thr 
    690                 695                 700                 


Glu Arg Asp Glu Leu Leu Lys Asp Leu Gln Gln Ser Ile Ala Arg Glu 
705                 710                 715                 720 


Pro Ser Ala Pro Ser Ile Pro Thr Pro Ala Tyr Gln Ser Ser Pro Ala 
                725                 730                 735     


Gly Gly His Ala Pro Thr Pro Pro Thr Pro Ala Pro Arg Thr Met Pro 
            740                 745                 750         


Pro Thr Lys Pro Gln Pro Pro Ala Arg Pro Pro Pro Pro Val Leu Pro 
        755                 760                 765             


Ala Asn Arg Ala Pro Ser Ala Thr Ala Pro Ser Pro Val Gly Ala Gly 
    770                 775                 780                 


Thr Ala Ala Pro Ala Pro Ser Gln Thr Pro Gly Ser Ala Pro Pro Pro 
785                 790                 795                 800 


Gln Ala Gln Gly Pro Pro Tyr Pro Thr Tyr Pro Gly Tyr Pro Gly Tyr 
                805                 810                 815     


Cys Gln Met Pro Met Pro Met Gly Tyr Asn Pro Tyr Ala Tyr Gly Gln 
            820                 825                 830         


Tyr Asn Met Pro Tyr Pro Pro Val Tyr His Gln Ser Pro Gly Gln Ala 
        835                 840                 845             


Pro Tyr Pro Gly Pro Gln Gln Pro Ser Tyr Pro Phe Pro Gln Pro Pro 
    850                 855                 860                 


Gln Gln Ser Tyr Tyr Pro Gln Gln 
865                 870         


<210>  2727
<211>  260
<212>  PRT
<213>  Homo Sapiens

<400>  2727

Cys Pro Arg Met Lys Arg Lys Ile Glu Arg Glu Ile Lys Cys Ser Pro 
1               5                   10                  15      


Ser Glu Ser Pro Leu Met Glu Lys Lys Asn Ser Leu Lys Glu Asp His 
            20                  25                  30          


Glu Glu Thr Lys Leu Ser Val Gly Asp Ile Glu Asn Lys His Pro Val 
        35                  40                  45              


Ser Glu Val Gly Pro Ala Thr Val Pro Leu Gln Ala Val Val Glu Glu 
    50                  55                  60                  


Arg Thr Val Ser Phe Lys Leu Gly Asp Leu Glu Glu Ala Pro Glu Arg 
65                  70                  75                  80  


Glu Arg Leu Pro Ser Val Asp Leu Lys Glu Glu Thr Ser Ile Asp Ser 
                85                  90                  95      


Thr Val Asn Gly Ala Val Gln Leu Pro Asn Gly Asn Leu Val Gln Phe 
            100                 105                 110         


Ser Gln Ala Val Ser Asn Gln Ile Asn Ser Ser Gly His Tyr Gln Tyr 
        115                 120                 125             


His Thr Val His Lys Asp Ser Gly Leu Tyr Lys Glu Leu Leu His Lys 
    130                 135                 140                 


Leu His Leu Ala Lys Val Gly Asp Cys Met Gly Asp Ser Gly Asp Lys 
145                 150                 155                 160 


Pro Leu Arg Arg Asn Asn Ser Tyr Thr Ser Tyr Thr Met Ala Ile Cys 
                165                 170                 175     


Gly Met Pro Leu Asp Ser Phe Arg Ala Lys Glu Gly Glu Gln Lys Gly 
            180                 185                 190         


Glu Glu Met Glu Lys Leu Thr Trp Pro Asn Ala Asp Ser Lys Lys Arg 
        195                 200                 205             


Ile Arg Met Asp Ser Tyr Thr Ser Tyr Cys Asn Ala Val Ser Asp Leu 
    210                 215                 220                 


His Ser Ala Ser Glu Ile Asp Met Ser Val Lys Ala Glu Met Gly Leu 
225                 230                 235                 240 


Gly Asp Arg Lys Gly Ser Asn Gly Ser Leu Glu Glu Trp Tyr Asp Gln 
                245                 250                 255     


Asp Lys Pro Glu 
            260 


<210>  2728
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  2728

Thr Asp Glu Ala Asn Thr Tyr Phe Lys Glu Trp Thr Cys Ser Ser Ser 
1               5                   10                  15      


Pro Ser Leu Pro Arg Ser Cys Lys Glu Ile Lys Asp Glu Cys Pro Ser 
            20                  25                  30          


Ala Phe Asp Gly Leu Tyr Phe Leu Arg Thr Glu Asn Gly Val Ile Tyr 
        35                  40                  45              


Gln Thr Phe Cys Asp Met Thr Ser Gly Gly Gly Gly Trp Thr Leu Val 
    50                  55                  60                  


Ala Ser Val His Glu Asn Asp Met Arg Gly Lys Cys Thr Val Gly Asp 
65                  70                  75                  80  


Arg Trp Ser Ser Gln Gln Gly Ser Lys Ala Val Tyr Pro Glu Gly Asp 
                85                  90                  95      


Gly Asn Trp Ala Asn Tyr Asn Thr Phe Gly Ser Ala Glu Ala Ala Thr 
            100                 105                 110         


Ser Asp Asp Tyr Lys Asn Pro Gly Tyr Tyr Asp Ile Gln Ala Lys Asp 
        115                 120                 125             


Leu Gly Ile Trp His Val Pro Asn Lys Ser Pro Met Gln His Trp Arg 
    130                 135                 140                 


Asn Ser Ser Leu Leu Arg Tyr Arg Thr Asp Thr Gly Phe Leu Gln Thr 
145                 150                 155                 160 


Leu Gly His Asn Leu Phe Gly Ile Tyr Gln Lys Tyr Pro Val Lys Tyr 
                165                 170                 175     


Gly Glu Gly Lys Cys Trp Thr Asp Asn Gly Pro Val Ile Pro Val Val 
            180                 185                 190         


Tyr Asp Phe Gly Asp Ala Gln Lys Thr Ala Ser Tyr Tyr Ser Pro Tyr 
        195                 200                 205             


Gly Gln Arg Glu Phe Thr Ala Gly Phe Val Gln Phe Arg Val Phe Asn 
    210                 215                 220                 


Asn Glu Arg Ala Ala Asn Ala Leu Cys Ala Gly Met Arg Val Thr Gly 
225                 230                 235                 240 


Cys Asn Thr Glu His His Cys Ile Gly Gly Gly Gly Tyr Phe Pro Glu 
                245                 250                 255     


Ala Ser Pro Gln Gln Cys Gly Asp Phe Ser Gly Phe Asp Trp Ser Gly 
            260                 265                 270         


Tyr Gly Thr His Val Gly Tyr Ser 
        275                 280 


<210>  2729
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  2729

Gln Glu Tyr Glu Asp Glu Glu Arg Leu Gly Glu Asp Glu Tyr Tyr Gln 
1               5                   10                  15      


Val Val Tyr Tyr Tyr Thr Val Thr Pro Ser Tyr Asp Asp Phe Ser Ala 
            20                  25                  30          


Asp Phe Thr Ile Asp Tyr Ser Ile Phe Glu Ser Glu Asp Arg Leu Asn 
        35                  40                  45              


Arg Leu Asp Lys Asp Ile Thr Glu Ala Ile Glu Thr Thr Ile Ser Leu 
    50                  55                  60                  


Glu Thr Ala Arg Ala Asp His Pro Lys Pro Val Thr Val Lys Pro Val 
65                  70                  75                  80  


Thr Thr Glu Pro Ser Pro Asp Leu Asn Asp Ala Val Ser Ser Leu Arg 
                85                  90                  95      


Ser Pro Ile Pro Leu Leu Leu Ser Cys Ala Phe Val Gln Val Gly Met 
            100                 105                 110         


Tyr Phe Met 
        115 


<210>  2730
<211>  551
<212>  PRT
<213>  Homo Sapiens

<400>  2730

Gly Asp Arg Arg Pro Leu Pro Val Asp Arg Ala Ala Gly Leu Lys Glu 
1               5                   10                  15      


Lys Thr Leu Ile Leu Leu Asp Val Ser Thr Lys Asn Pro Val Arg Thr 
            20                  25                  30          


Val Asn Glu Asn Phe Leu Ser Leu Gln Leu Asp Pro Ser Ile Ile His 
        35                  40                  45              


Asp Gly Trp Leu Asp Phe Leu Ser Ser Lys Arg Leu Val Thr Leu Ala 
    50                  55                  60                  


Arg Gly Leu Ser Pro Ala Phe Leu Arg Phe Gly Gly Lys Arg Thr Asp 
65                  70                  75                  80  


Phe Leu Gln Phe Gln Asn Leu Arg Asn Pro Ala Lys Ser Arg Gly Gly 
                85                  90                  95      


Pro Gly Pro Asp Tyr Tyr Leu Lys Asn Tyr Glu Asp Asp Ile Val Arg 
            100                 105                 110         


Ser Asp Val Ala Leu Asp Lys Gln Lys Gly Cys Lys Ile Ala Gln His 
        115                 120                 125             


Pro Asp Val Met Leu Glu Leu Gln Arg Glu Lys Ala Ala Gln Met His 
    130                 135                 140                 


Leu Val Leu Leu Lys Glu Gln Phe Ser Asn Thr Tyr Ser Asn Leu Ile 
145                 150                 155                 160 


Leu Thr Ala Arg Ser Leu Asp Lys Leu Tyr Asn Phe Ala Asp Cys Ser 
                165                 170                 175     


Gly Leu His Leu Ile Phe Ala Leu Asn Ala Leu Arg Arg Asn Pro Asn 
            180                 185                 190         


Asn Ser Trp Asn Ser Ser Ser Ala Leu Ser Leu Leu Lys Tyr Ser Ala 
        195                 200                 205             


Ser Lys Lys Tyr Asn Ile Ser Trp Glu Leu Gly Asn Glu Pro Asn Asn 
    210                 215                 220                 


Tyr Arg Thr Met His Gly Arg Ala Val Asn Gly Ser Gln Leu Gly Lys 
225                 230                 235                 240 


Asp Tyr Ile Gln Leu Lys Ser Leu Leu Gln Pro Ile Arg Ile Tyr Ser 
                245                 250                 255     


Arg Ala Ser Leu Tyr Gly Pro Asn Ile Gly Arg Pro Arg Lys Asn Val 
            260                 265                 270         


Ile Ala Leu Leu Asp Gly Phe Met Lys Val Ala Gly Ser Thr Val Asp 
        275                 280                 285             


Ala Val Thr Trp Gln His Cys Tyr Ile Asp Gly Arg Val Val Lys Val 
    290                 295                 300                 


Met Asp Phe Leu Lys Thr Arg Leu Leu Asp Thr Leu Ser Asp Gln Ile 
305                 310                 315                 320 


Arg Lys Ile Gln Lys Val Val Asn Thr Tyr Thr Pro Gly Lys Lys Ile 
                325                 330                 335     


Trp Leu Glu Gly Val Val Thr Thr Ser Ala Gly Gly Thr Asn Asn Leu 
            340                 345                 350         


Ser Asp Ser Tyr Ala Ala Gly Phe Leu Trp Leu Asn Thr Leu Gly Met 
        355                 360                 365             


Leu Ala Asn Gln Gly Ile Asp Val Val Ile Arg His Ser Phe Phe Asp 
    370                 375                 380                 


His Gly Tyr Asn His Leu Val Asp Gln Asn Phe Asn Pro Leu Pro Asp 
385                 390                 395                 400 


Tyr Trp Leu Ser Leu Leu Tyr Lys Arg Leu Ile Gly Pro Lys Val Leu 
                405                 410                 415     


Ala Val His Val Ala Gly Leu Gln Arg Lys Pro Arg Pro Gly Arg Val 
            420                 425                 430         


Ile Arg Asp Lys Leu Arg Ile Tyr Ala His Cys Thr Asn His His Asn 
        435                 440                 445             


His Asn Tyr Val Arg Gly Ser Ile Thr Leu Phe Ile Ile Asn Leu His 
    450                 455                 460                 


Arg Ser Arg Lys Lys Ile Lys Leu Thr Gly Thr Leu Arg Asp Lys Leu 
465                 470                 475                 480 


Val His Gln Tyr Leu Leu Gln Pro Tyr Gly Gln Glu Gly Leu Lys Ser 
                485                 490                 495     


Lys Ser Val Gln Leu Asn Gly Gln Pro Leu Val Met Val Asp Asp Gly 
            500                 505                 510         


Thr Leu Pro Glu Leu Lys Pro Arg Pro Leu Arg Ala Gly Arg Thr Leu 
        515                 520                 525             


Val Ile Pro Pro Val Thr Met Gly Phe Phe Val Val Lys Asn Val Asn 
    530                 535                 540                 


Ala Leu Ala Cys Arg Tyr Arg 
545                 550     


<210>  2731
<211>  299
<212>  PRT
<213>  Homo Sapiens

<400>  2731

Ala Ala Ala Ser Ser Leu Glu Met Leu Ser Arg Glu Phe Glu Thr Cys 
1               5                   10                  15      


Ala Phe Ser Phe Ser Ser Leu Pro Arg Ser Cys Lys Glu Ile Lys Glu 
            20                  25                  30          


Arg Cys His Ser Ala Gly Asp Gly Leu Tyr Phe Leu Arg Thr Lys Asn 
        35                  40                  45              


Gly Val Val Tyr Gln Thr Phe Cys Asp Met Thr Ser Gly Gly Gly Gly 
    50                  55                  60                  


Trp Thr Leu Val Ala Ser Val His Glu Asn Asp Met His Gly Lys Cys 
65                  70                  75                  80  


Thr Val Gly Asp Arg Trp Ser Ser Gln Gln Gly Asn Lys Ala Asp Tyr 
                85                  90                  95      


Pro Glu Gly Asp Gly Asn Trp Ala Asn Tyr Asn Thr Phe Gly Ser Ala 
            100                 105                 110         


Glu Ala Ala Thr Ser Asp Asp Tyr Lys Asn Pro Gly Tyr Tyr Asp Ile 
        115                 120                 125             


Gln Ala Lys Asp Leu Gly Ile Trp His Val Pro Asn Lys Ser Pro Met 
    130                 135                 140                 


Gln His Trp Arg Asn Ser Ala Leu Leu Arg Tyr Arg Thr Asn Thr Gly 
145                 150                 155                 160 


Phe Leu Gln Arg Leu Gly His Asn Leu Phe Gly Ile Tyr Gln Lys Tyr 
                165                 170                 175     


Pro Val Lys Tyr Arg Ser Gly Lys Cys Trp Asn Asp Asn Gly Pro Ala 
            180                 185                 190         


Ile Pro Val Val Tyr Asp Phe Gly Asp Ala Lys Lys Thr Ala Ser Tyr 
        195                 200                 205             


Tyr Ser Pro Tyr Gly Gln Arg Glu Phe Val Ala Gly Phe Val Gln Phe 
    210                 215                 220                 


Arg Val Phe Asn Asn Glu Arg Ala Ala Asn Ala Leu Cys Ala Gly Ile 
225                 230                 235                 240 


Lys Val Thr Gly Cys Asn Thr Glu His His Cys Ile Gly Gly Gly Gly 
                245                 250                 255     


Phe Phe Pro Gln Gly Lys Pro Arg Gln Cys Gly Asp Phe Ser Ala Phe 
            260                 265                 270         


Asp Trp Asp Gly Tyr Gly Thr His Val Lys Ser Ser Cys Ser Arg Glu 
        275                 280                 285             


Ile Thr Glu Ala Ala Val Leu Leu Phe Tyr Arg 
    290                 295                 


<210>  2732
<211>  88
<212>  PRT
<213>  Homo Sapiens

<400>  2732

Val Lys Glu Gly Ile Glu Lys Ala Gly Val Cys Pro Ala Asp Asn Val 
1               5                   10                  15      


Arg Cys Phe Lys Ser Asp Pro Pro Gln Cys His Thr Asp Gln Asp Cys 
            20                  25                  30          


Leu Gly Glu Arg Lys Cys Cys Tyr Leu His Cys Gly Phe Lys Cys Val 
        35                  40                  45              


Ile Pro Val Lys Glu Leu Glu Glu Gly Gly Asn Lys Asp Glu Asp Val 
    50                  55                  60                  


Ser Arg Pro Tyr Pro Glu Pro Gly Trp Glu Ala Lys Cys Pro Gly Ser 
65                  70                  75                  80  


Ser Ser Thr Arg Cys Pro Gln Lys 
                85              


<210>  2733
<211>  433
<212>  PRT
<213>  Homo Sapiens

<400>  2733

Glu Glu Thr Cys Pro Ser Phe Thr Arg Leu Ser Phe His Ser Ala Val 
1               5                   10                  15      


Val Gly Thr Gly Leu Asn Val Arg Leu Met Leu Tyr Thr Arg Lys Asn 
            20                  25                  30          


Leu Thr Cys Ala Gln Thr Ile Asn Ser Ser Ala Phe Gly Asn Leu Asn 
        35                  40                  45              


Val Thr Lys Lys Thr Thr Phe Ile Val His Gly Phe Arg Pro Thr Gly 
    50                  55                  60                  


Ser Pro Pro Val Trp Met Asp Asp Leu Val Lys Gly Leu Leu Ser Val 
65                  70                  75                  80  


Glu Asp Met Asn Val Val Val Val Asp Trp Asn Arg Gly Ala Thr Thr 
                85                  90                  95      


Leu Ile Tyr Thr His Ala Ser Ser Lys Thr Arg Lys Val Ala Met Val 
            100                 105                 110         


Leu Lys Glu Phe Ile Asp Gln Met Leu Ala Glu Gly Ala Ser Leu Asp 
        115                 120                 125             


Asp Ile Tyr Met Ile Gly Val Ser Leu Gly Ala His Ile Ser Gly Phe 
    130                 135                 140                 


Val Gly Glu Met Tyr Asp Gly Trp Leu Gly Arg Ile Thr Gly Leu Asp 
145                 150                 155                 160 


Pro Ala Gly Pro Leu Phe Asn Gly Lys Pro His Gln Asp Arg Leu Asp 
                165                 170                 175     


Pro Ser Asp Ala Gln Phe Val Asp Val Ile His Ser Asp Thr Asp Ala 
            180                 185                 190         


Leu Gly Tyr Lys Glu Pro Leu Gly Asn Ile Asp Phe Tyr Pro Asn Gly 
        195                 200                 205             


Gly Leu Asp Gln Pro Gly Cys Pro Lys Thr Ile Leu Gly Gly Phe Gln 
    210                 215                 220                 


Tyr Phe Lys Cys Asp His Gln Arg Ser Val Tyr Leu Tyr Leu Ser Ser 
225                 230                 235                 240 


Leu Arg Glu Ser Cys Thr Ile Thr Ala Tyr Pro Cys Asp Ser Tyr Gln 
                245                 250                 255     


Asp Tyr Arg Asn Gly Lys Cys Val Ser Cys Gly Thr Ser Gln Lys Glu 
            260                 265                 270         


Ser Cys Pro Leu Leu Gly Tyr Tyr Ala Asp Asn Trp Lys Asp His Leu 
        275                 280                 285             


Arg Gly Lys Asp Pro Pro Met Thr Lys Ala Phe Phe Asp Thr Ala Glu 
    290                 295                 300                 


Glu Ser Pro Phe Cys Met Tyr His Tyr Phe Val Asp Ile Ile Thr Trp 
305                 310                 315                 320 


Asn Lys Asn Val Arg Arg Gly Asp Ile Thr Ile Lys Leu Arg Asp Lys 
                325                 330                 335     


Ala Gly Asn Thr Thr Glu Ser Lys Ile Asn His Glu Pro Thr Thr Phe 
            340                 345                 350         


Gln Lys Tyr His Gln Val Ser Leu Leu Ala Arg Phe Asn Gln Asp Leu 
        355                 360                 365             


Asp Lys Val Ala Ala Ile Ser Leu Met Phe Ser Thr Gly Ser Leu Ile 
    370                 375                 380                 


Gly Pro Arg Tyr Lys Leu Arg Ile Leu Arg Met Lys Leu Arg Ser Leu 
385                 390                 395                 400 


Ala His Pro Glu Arg Pro Gln Leu Cys Arg Tyr Asp Leu Val Leu Met 
                405                 410                 415     


Glu Asn Val Glu Thr Val Phe Gln Pro Ile Leu Cys Pro Glu Leu Gln 
            420                 425                 430         


Leu 
    


<210>  2734
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  2734

Gln Glu Phe Asp Pro His Thr Val Met Gln Arg Asn Tyr Asn Val Ala 
1               5                   10                  15      


Arg Val Ser Gly Val Trp Tyr Ser Ile Phe Met Ala Ser Asp Asp Leu 
            20                  25                  30          


Asn Arg Ile Lys Glu Asn Gly Asp Leu Arg Val Phe Val Arg Asn Ile 
        35                  40                  45              


Glu His Leu Lys Asn Gly Ser Leu Ile Phe Asp Phe Glu Tyr Met Val 
    50                  55                  60                  


Gln Gly Glu Cys Val Ala Val Val Val Val Cys Glu Lys Thr Glu Lys 
65                  70                  75                  80  


Asn Gly Glu Tyr Ser Ile Asn Tyr Glu Gly Gln Asn Thr Val Ala Val 
                85                  90                  95      


Ser Glu Thr Asp Tyr Arg Leu Phe Ile Thr Phe His Leu Gln Asn Phe 
            100                 105                 110         


Arg Asn Gly Thr Glu Thr His Thr Leu Ala Leu Tyr Glu Thr Cys Glu 
        115                 120                 125             


Lys Tyr Gly Leu Gly Ser Gln Asn Ile Ile Asp Leu Thr Asn Lys Asp 
    130                 135                 140                 


Pro Cys Tyr Ser Lys His Tyr Arg Ser Pro Pro Arg Pro Pro Met Arg 
145                 150                 155                 160 


Trp 
    


<210>  2735
<211>  221
<212>  PRT
<213>  Homo Sapiens

<400>  2735

Phe Thr Ile Asn Cys Ser Gly Phe Asp Gln His Gly Val Asp Pro Ala 
1               5                   10                  15      


Val Phe Gln Ala Val Phe Asp Arg Lys Ala Phe Arg Pro Phe Thr Asn 
            20                  25                  30          


Tyr Ser Ile Pro Thr Arg Val Asn Ile Ser Phe Thr Leu Ser Ala Ile 
        35                  40                  45              


Leu Gly Val Asp Ala Gln Leu Gln Leu Leu Thr Ser Phe Leu Trp Met 
    50                  55                  60                  


Asp Leu Val Trp Asp Asn Pro Phe Ile Asn Trp Asn Pro Lys Glu Cys 
65                  70                  75                  80  


Val Gly Ile Asn Lys Leu Thr Val Leu Ala Glu Asn Leu Trp Leu Pro 
                85                  90                  95      


Asp Ile Phe Ile Val Glu Ser Met Asp Val Asp Gln Thr Pro Ser Gly 
            100                 105                 110         


Leu Thr Ala Tyr Ile Ser Ser Glu Gly Arg Ile Lys Tyr Asp Lys Pro 
        115                 120                 125             


Met Arg Val Thr Ser Ile Cys Asn Leu Asp Ile Phe Tyr Phe Pro Phe 
    130                 135                 140                 


Asp Gln Gln Asn Cys Thr Phe Thr Phe Ser Ser Phe Leu Tyr Thr Val 
145                 150                 155                 160 


Asp Ser Met Leu Leu Gly Met Asp Lys Glu Val Trp Glu Ile Thr Asp 
                165                 170                 175     


Thr Ser Arg Lys Val Ile Gln Thr Gln Gly Glu Trp Glu Leu Leu Gly 
            180                 185                 190         


Ile Asn Lys Ala Thr Pro Lys Met Ser Met Gly Asn Asn Leu Tyr Asp 
        195                 200                 205             


Gln Ile Met Phe Tyr Val Ala Ile Arg Arg Arg Pro Ser 
    210                 215                 220     


<210>  2736
<211>  449
<212>  PRT
<213>  Homo Sapiens

<400>  2736

Phe Pro Lys Pro Gly Gly Ser Gln Asp Lys Ser Leu His Asn Arg Glu 
1               5                   10                  15      


Leu Ser Ala Glu Arg Pro Leu Asn Glu Gln Ile Ala Glu Ala Glu Glu 
            20                  25                  30          


Asp Lys Ile Lys Lys Thr Tyr Pro Pro Glu Asn Lys Pro Gly Gln Ser 
        35                  40                  45              


Asn Tyr Ser Phe Val Asp Asn Leu Asn Leu Leu Lys Ala Ile Thr Glu 
    50                  55                  60                  


Lys Glu Lys Ile Glu Lys Glu Arg Gln Ser Ile Arg Ser Ser Pro Leu 
65                  70                  75                  80  


Asp Asn Lys Leu Asn Val Glu Asp Val Asp Ser Thr Lys Asn Arg Lys 
                85                  90                  95      


Leu Ile Asp Asp Tyr Asp Ser Thr Lys Ser Gly Leu Asp His Lys Phe 
            100                 105                 110         


Gln Asp Asp Pro Asp Gly Leu His Gln Leu Asp Gly Thr Pro Leu Thr 
        115                 120                 125             


Ala Glu Asp Ile Val His Lys Ile Ala Ala Arg Ile Tyr Glu Glu Asn 
    130                 135                 140                 


Asp Arg Ala Ala Phe Asp Lys Ile Val Ser Lys Leu Leu Asn Leu Gly 
145                 150                 155                 160 


Leu Ile Thr Glu Ser Gln Ala His Thr Leu Glu Asp Glu Val Ala Glu 
                165                 170                 175     


Val Leu Gln Lys Leu Ile Ser Lys Glu Ala Asn Asn Tyr Glu Glu Asp 
            180                 185                 190         


Pro Asn Lys Pro Thr Ser Trp Thr Glu Asn Gln Ala Gly Lys Ile Pro 
        195                 200                 205             


Glu Lys Val Thr Pro Met Ala Ala Ile Gln Asp Gly Leu Ala Lys Gly 
    210                 215                 220                 


Glu Asn Asp Glu Thr Val Ser Asn Thr Leu Thr Leu Thr Asn Gly Leu 
225                 230                 235                 240 


Glu Arg Arg Thr Lys Thr Tyr Ser Glu Asp Asn Phe Glu Glu Leu Gln 
                245                 250                 255     


Tyr Phe Pro Asn Phe Tyr Ala Leu Leu Lys Ser Ile Asp Ser Glu Lys 
            260                 265                 270         


Glu Ala Lys Glu Lys Glu Thr Leu Ile Thr Ile Met Lys Thr Leu Ile 
        275                 280                 285             


Asp Phe Val Lys Met Met Val Lys Tyr Gly Thr Ile Ser Pro Glu Glu 
    290                 295                 300                 


Gly Val Ser Tyr Leu Glu Asn Leu Asp Glu Met Ile Ala Leu Gln Thr 
305                 310                 315                 320 


Lys Asn Lys Leu Glu Lys Asn Ala Thr Asp Asn Ile Ser Lys Leu Phe 
                325                 330                 335     


Pro Ala Pro Ser Glu Lys Ser His Glu Glu Thr Asp Ser Thr Lys Glu 
            340                 345                 350         


Glu Ala Ala Lys Met Glu Lys Glu Tyr Gly Ser Leu Lys Asp Ser Thr 
        355                 360                 365             


Lys Asp Asp Asn Ser Asn Pro Gly Gly Lys Thr Asp Glu Pro Lys Gly 
    370                 375                 380                 


Lys Thr Glu Ala Tyr Leu Glu Ala Ile Arg Lys Asn Ile Glu Trp Leu 
385                 390                 395                 400 


Lys Lys His Asp Lys Lys Gly Asn Lys Glu Asp Tyr Asp Leu Ser Lys 
                405                 410                 415     


Met Arg Asp Phe Ile Asn Lys Gln Ala Asp Ala Tyr Val Glu Lys Gly 
            420                 425                 430         


Ile Leu Asp Lys Glu Glu Ala Glu Ala Ile Lys Arg Ile Tyr Ser Ser 
        435                 440                 445             


Leu 
    


<210>  2737
<211>  310
<212>  PRT
<213>  Homo Sapiens

<400>  2737

Leu Glu Arg Ser Thr Asn Ser Phe Ser Tyr Ser Ser Tyr His Thr Leu 
1               5                   10                  15      


Glu Glu Ile Tyr Ser Trp Ile Asp Asn Phe Val Met Glu His Ser Asp 
            20                  25                  30          


Ile Val Ser Lys Ile Gln Ile Gly Asn Ser Phe Glu Asn Gln Ser Ile 
        35                  40                  45              


Leu Val Leu Lys Phe Ser Thr Gly Gly Ser Arg His Pro Ala Ile Trp 
    50                  55                  60                  


Ile Asp Thr Gly Ile His Ser Arg Glu Trp Ile Thr His Ala Thr Gly 
65                  70                  75                  80  


Ile Trp Thr Ala Asn Lys Ile Val Ser Asp Tyr Gly Lys Asp Arg Val 
                85                  90                  95      


Leu Thr Asp Ile Leu Asn Ala Met Asp Ile Phe Ile Glu Leu Val Thr 
            100                 105                 110         


Asn Pro Asp Gly Phe Ala Phe Thr His Ser Met Asn Arg Leu Trp Arg 
        115                 120                 125             


Lys Asn Lys Ser Ile Arg Pro Gly Ile Phe Cys Ile Gly Val Asp Leu 
    130                 135                 140                 


Asn Arg Asn Trp Lys Ser Gly Phe Gly Gly Asn Gly Ser Asn Ser Asn 
145                 150                 155                 160 


Pro Cys Ser Glu Thr Tyr His Gly Pro Ser Pro Gln Ser Glu Pro Glu 
                165                 170                 175     


Val Ala Ala Ile Val Asn Phe Ile Thr Ala His Gly Asn Phe Lys Ala 
            180                 185                 190         


Leu Ile Ser Ile His Ser Tyr Ser Gln Met Leu Met Tyr Pro Tyr Gly 
        195                 200                 205             


Arg Leu Leu Glu Pro Val Ser Asn Gln Arg Glu Leu Tyr Asp Leu Ala 
    210                 215                 220                 


Lys Asp Ala Val Glu Ala Leu Tyr Lys Val His Gly Ile Glu Tyr Ile 
225                 230                 235                 240 


Phe Gly Ser Ile Ser Thr Thr Leu Tyr Val Ala Ser Gly Ile Thr Val 
                245                 250                 255     


Asp Trp Ala Tyr Asp Ser Gly Ile Lys Tyr Ala Phe Ser Phe Glu Leu 
            260                 265                 270         


Arg Asp Thr Gly Gln Tyr Gly Phe Leu Leu Pro Ala Thr Gln Ile Ile 
        275                 280                 285             


Pro Thr Ala Gln Glu Thr Trp Met Ala Leu Arg Thr Ile Met Glu His 
    290                 295                 300                 


Thr Leu Asn His Pro Tyr 
305                 310 


<210>  2738
<211>  974
<212>  PRT
<213>  Homo Sapiens

<400>  2738

His Ala Lys Pro Gly Ser Tyr Ser Ile Glu Val Leu Leu Val Val Asp 
1               5                   10                  15      


Asp Ser Val Val Arg Phe His Gly Lys Glu His Val Gln Asn Tyr Val 
            20                  25                  30          


Leu Thr Leu Met Asn Ile Val Asp Glu Ile Tyr His Asp Glu Ser Leu 
        35                  40                  45              


Gly Val His Ile Asn Ile Ala Leu Val Arg Leu Ile Met Val Gly Tyr 
    50                  55                  60                  


Arg Gln Ser Leu Ser Leu Ile Glu Arg Gly Asn Pro Ser Arg Ser Leu 
65                  70                  75                  80  


Glu Gln Val Cys Arg Trp Ala His Ser Gln Gln Arg Gln Asp Pro Ser 
                85                  90                  95      


His Ala Glu His His Asp His Val Val Phe Leu Thr Arg Gln Asp Phe 
            100                 105                 110         


Gly Pro Ser Gly Met Gln Gly Tyr Ala Pro Val Thr Gly Met Cys His 
        115                 120                 125             


Pro Leu Arg Ser Cys Ala Leu Asn His Glu Asp Gly Phe Ser Ser Ala 
    130                 135                 140                 


Phe Val Ile Ala His Glu Thr Gly His Val Leu Gly Met Glu His Asp 
145                 150                 155                 160 


Gly Gln Gly Asn Gly Cys Ala Asp Glu Thr Ser Leu Gly Ser Val Met 
                165                 170                 175     


Ala Pro Leu Val Gln Ala Ala Phe His Arg Phe His Trp Ser Arg Cys 
            180                 185                 190         


Ser Lys Leu Glu Leu Ser Arg Tyr Leu Pro Ser Tyr Asp Cys Leu Leu 
        195                 200                 205             


Asp Asp Pro Phe Asp Pro Ala Trp Pro Gln Pro Pro Glu Leu Pro Gly 
    210                 215                 220                 


Ile Asn Tyr Ser Met Asp Glu Gln Cys Arg Phe Asp Phe Gly Ser Gly 
225                 230                 235                 240 


Tyr Gln Thr Cys Leu Ala Phe Arg Thr Phe Glu Pro Cys Lys Gln Leu 
                245                 250                 255     


Trp Cys Ser His Pro Asp Asn Pro Tyr Phe Cys Lys Thr Lys Lys Gly 
            260                 265                 270         


Pro Pro Leu Asp Gly Thr Glu Cys Ala Pro Gly Lys Trp Cys Phe Lys 
        275                 280                 285             


Gly His Cys Ile Trp Lys Ser Pro Glu Gln Thr Tyr Gly Gln Asp Gly 
    290                 295                 300                 


Gly Trp Ser Ser Trp Thr Lys Phe Gly Ser Cys Ser Arg Ser Cys Gly 
305                 310                 315                 320 


Gly Gly Val Arg Ser Arg Ser Arg Ser Cys Asn Asn Pro Ser Pro Ala 
                325                 330                 335     


Tyr Gly Gly Arg Leu Cys Leu Gly Pro Met Phe Glu Tyr Gln Val Cys 
            340                 345                 350         


Asn Ser Glu Glu Cys Pro Gly Thr Tyr Glu Asp Phe Arg Ala Gln Gln 
        355                 360                 365             


Cys Ala Lys Arg Asn Ser Tyr Tyr Val His Gln Asn Ala Lys His Ser 
    370                 375                 380                 


Trp Val Pro Tyr Glu Pro Asp Asp Asp Ala Gln Lys Cys Glu Leu Ile 
385                 390                 395                 400 


Cys Gln Ser Ala Asp Thr Gly Asp Val Val Phe Met Asn Gln Val Val 
                405                 410                 415     


His Asp Gly Thr Arg Cys Ser Tyr Arg Asp Pro Tyr Ser Val Cys Ala 
            420                 425                 430         


Arg Gly Glu Cys Val Pro Val Gly Cys Asp Lys Glu Val Gly Ser Met 
        435                 440                 445             


Lys Ala Asp Asp Lys Cys Gly Val Cys Gly Gly Asp Asn Ser His Cys 
    450                 455                 460                 


Arg Thr Val Lys Gly Thr Leu Gly Lys Ala Ser Lys Gln Ala Gly Ala 
465                 470                 475                 480 


Leu Lys Leu Val Gln Ile Pro Ala Gly Ala Arg His Ile Gln Ile Glu 
                485                 490                 495     


Ala Leu Glu Lys Ser Pro His Arg Ile Val Val Lys Asn Gln Val Thr 
            500                 505                 510         


Gly Ser Phe Ile Leu Asn Pro Lys Gly Lys Glu Ala Thr Ser Arg Thr 
        515                 520                 525             


Phe Thr Ala Met Gly Leu Glu Trp Glu Asp Ala Val Glu Asp Ala Lys 
    530                 535                 540                 


Glu Ser Leu Lys Thr Ser Gly Pro Leu Pro Glu Ala Ile Ala Ile Leu 
545                 550                 555                 560 


Ala Leu Pro Pro Thr Glu Gly Gly Pro Arg Ser Ser Leu Ala Tyr Lys 
                565                 570                 575     


Tyr Val Ile His Glu Asp Leu Leu Pro Leu Ile Gly Ser Asn Asn Val 
            580                 585                 590         


Leu Leu Glu Glu Met Asp Thr Tyr Glu Trp Ala Leu Lys Ser Trp Ala 
        595                 600                 605             


Pro Cys Ser Lys Ala Cys Gly Gly Gly Ile Gln Phe Thr Lys Tyr Gly 
    610                 615                 620                 


Cys Arg Arg Arg Arg Asp His His Met Val Gln Arg His Leu Cys Asp 
625                 630                 635                 640 


His Lys Lys Arg Pro Lys Pro Ile Arg Arg Arg Cys Asn Gln His Pro 
                645                 650                 655     


Cys Ser Gln Pro Val Trp Val Thr Glu Glu Trp Gly Ala Cys Ser Arg 
            660                 665                 670         


Ser Cys Gly Lys Leu Gly Val Gln Thr Arg Gly Ile Gln Cys Leu Leu 
        675                 680                 685             


Pro Leu Ser Asn Gly Thr His Lys Val Met Pro Ala Lys Ala Cys Ala 
    690                 695                 700                 


Gly Asp Arg Pro Glu Ala Arg Arg Pro Cys Leu Arg Val Pro Cys Pro 
705                 710                 715                 720 


Ala Gln Trp Arg Leu Gly Ala Trp Ser Gln Cys Ser Ala Thr Cys Gly 
                725                 730                 735     


Glu Gly Ile Gln Gln Arg Gln Val Val Cys Arg Thr Asn Ala Asn Ser 
            740                 745                 750         


Leu Gly His Cys Glu Gly Asp Arg Pro Asp Thr Val Gln Val Cys Ser 
        755                 760                 765             


Leu Pro Ala Cys Gly Gly Asn His Gln Asn Ser Thr Val Arg Ala Asp 
    770                 775                 780                 


Val Trp Glu Leu Gly Thr Pro Glu Gly Gln Trp Val Pro Gln Ser Glu 
785                 790                 795                 800 


Pro Leu His Pro Ile Asn Lys Ile Ser Ser Thr Glu Pro Cys Thr Gly 
                805                 810                 815     


Asp Arg Ser Val Phe Cys Gln Met Glu Val Leu Asp Arg Tyr Cys Ser 
            820                 825                 830         


Ile Pro Gly Tyr His Arg Leu Cys Cys Val Ser Cys Ile Lys Lys Ala 
        835                 840                 845             


Ser Gly Pro Asn Pro Gly Pro Asp Pro Gly Pro Thr Ser Leu Pro Pro 
    850                 855                 860                 


Phe Ser Thr Pro Gly Ser Pro Leu Pro Gly Pro Gln Asp Pro Ala Asp 
865                 870                 875                 880 


Ala Ala Glu Pro Pro Gly Lys Pro Thr Gly Ser Glu Asp His Gln His 
                885                 890                 895     


Gly Arg Ala Thr Gln Leu Pro Gly Ala Leu Asp Thr Ser Ser Pro Gly 
            900                 905                 910         


Thr Gln His Pro Phe Ala Pro Glu Thr Pro Ile Pro Gly Ala Ser Trp 
        915                 920                 925             


Ser Ile Ser Pro Thr Thr Pro Gly Gly Leu Pro Trp Gly Trp Thr Gln 
    930                 935                 940                 


Thr Pro Thr Pro Val Pro Glu Asp Lys Gly Gln Pro Gly Glu Asp Leu 
945                 950                 955                 960 


Arg His Pro Gly Thr Ser Leu Pro Ala Ala Ser Pro Val Thr 
                965                 970                 


<210>  2739
<211>  419
<212>  PRT
<213>  Homo Sapiens

<400>  2739

Met Ser Arg Lys Ile Ser Lys Glu Ser Lys Lys Val Asn Ile Ser Ser 
1               5                   10                  15      


Ser Leu Glu Ser Glu Asp Ile Ser Leu Glu Thr Thr Val Pro Thr Asp 
            20                  25                  30          


Asp Ile Ser Ser Ser Glu Glu Arg Glu Gly Lys Val Arg Ile Thr Arg 
        35                  40                  45              


Gln Leu Ile Glu Arg Lys Glu Leu Leu His Asn Ile Gln Leu Leu Lys 
    50                  55                  60                  


Ile Glu Leu Ser Gln Lys Thr Met Met Ile Asp Asn Leu Lys Val Asp 
65                  70                  75                  80  


Tyr Leu Thr Lys Ile Glu Glu Leu Glu Glu Lys Leu Asn Asp Ala Leu 
                85                  90                  95      


His Gln Lys Gln Leu Leu Thr Leu Arg Leu Asp Asn Gln Leu Ala Phe 
            100                 105                 110         


Gln Gln Lys Asp Ala Ser Lys Tyr Gln Glu Leu Met Lys Gln Glu Met 
        115                 120                 125             


Glu Thr Ile Leu Leu Arg Gln Lys Gln Leu Glu Glu Thr Asn Leu Gln 
    130                 135                 140                 


Leu Arg Glu Lys Ala Gly Asp Val Arg Arg Asn Leu Arg Asp Phe Glu 
145                 150                 155                 160 


Leu Thr Glu Glu Gln Tyr Val Lys Leu Lys Ala Phe Pro Glu Asp Gln 
                165                 170                 175     


Leu Ser Ile Pro Glu Tyr Val Ser Val Arg Phe Tyr Glu Leu Val Asn 
            180                 185                 190         


Pro Leu Arg Lys Glu Ile Cys Glu Leu Gln Val Lys Lys Asn Ile Leu 
        195                 200                 205             


Ala Glu Glu Leu Ser Thr Asn Lys Asn Gln Leu Lys Gln Leu Thr Glu 
    210                 215                 220                 


Thr Tyr Glu Glu Asp Arg Lys Asn Tyr Ser Glu Val Gln Ile Arg Cys 
225                 230                 235                 240 


Gln Arg Leu Ala Leu Glu Leu Ala Asp Thr Lys Gln Leu Ile Gln Gln 
                245                 250                 255     


Gly Asp Tyr Arg Gln Glu Asn Tyr Asp Lys Val Lys Ser Glu Arg Asp 
            260                 265                 270         


Ala Leu Glu Gln Glu Val Ile Glu Leu Arg Arg Lys His Glu Ile Leu 
        275                 280                 285             


Glu Ala Ser His Met Ile Gln Thr Lys Glu Arg Ser Glu Leu Ser Lys 
    290                 295                 300                 


Glu Val Val Thr Leu Glu Gln Thr Val Thr Leu Leu Gln Lys Asp Lys 
305                 310                 315                 320 


Glu Tyr Leu Asn Arg Gln Asn Met Glu Leu Ser Val Arg Cys Ala His 
                325                 330                 335     


Glu Glu Asp Arg Leu Glu Arg Leu Gln Ala Gln Leu Glu Glu Ser Lys 
            340                 345                 350         


Lys Ala Arg Glu Glu Met Tyr Glu Lys Tyr Val Ala Ser Arg Asp His 
        355                 360                 365             


Tyr Lys Thr Glu Tyr Glu Asn Lys Leu His Asp Glu Leu Glu Gln Ile 
    370                 375                 380                 


Arg Leu Lys Thr Asn Gln Glu Ile Asp Gln Leu Arg Asn Ala Ser Arg 
385                 390                 395                 400 


Glu Met Tyr Glu Arg Glu Asn Arg Asn Leu Arg Glu Ala Arg Asp Asn 
                405                 410                 415     


Ala Val Ala 
            


<210>  2740
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  2740

Asn Gly Ile Gln Gly Phe Phe Tyr Pro Trp Ser Cys Glu Gly Asp Ile 
1               5                   10                  15      


Trp Asp Arg Glu Ser Cys Gly Gly Gln Ala Ala Ile Asp Ser Pro Asn 
            20                  25                  30          


Leu Cys Leu Arg Leu Arg Cys Cys Tyr Arg Asn Gly Val Cys Tyr His 
        35                  40                  45              


Gln Arg Pro Asp Glu Asn Val Arg Arg Lys His Met 
    50                  55                  60  


<210>  2741
<211>  334
<212>  PRT
<213>  Homo Sapiens

<400>  2741

Ala Thr Ile Ser Cys Arg Asn Glu Glu Gly Lys Ala Val Asp Trp Phe 
1               5                   10                  15      


Thr Phe Tyr Lys Leu Pro Lys Lys Gln Asn Lys Glu Ser Gly Glu Thr 
            20                  25                  30          


Gly Leu Glu Tyr Leu Tyr Leu Asp Ser Thr Thr Arg Ser Trp Arg Lys 
        35                  40                  45              


Ser Glu Gln Leu Met Asn Asp Thr Lys Ser Val Leu Gly Arg Thr Leu 
    50                  55                  60                  


Gln Gln Leu Tyr Glu Ala Tyr Ala Ser Lys Ser Asn Asn Thr Ala Tyr 
65                  70                  75                  80  


Leu Ile Tyr Asn Asp Gly Val Pro Lys Pro Val Asn Tyr Ser Arg Lys 
                85                  90                  95      


Tyr Gly His Thr Lys Gly Leu Leu Leu Trp Asn Arg Val Gln Gly Phe 
            100                 105                 110         


Trp Leu Ile His Ser Ile Pro Gln Phe Pro Pro Ile Pro Glu Glu Gly 
        115                 120                 125             


Tyr Asp Tyr Pro Pro Thr Gly Arg Arg Asn Gly Gln Ser Gly Ile Cys 
    130                 135                 140                 


Ile Thr Phe Lys Tyr Asn Gln Tyr Glu Ala Ile Asp Ser Gln Leu Leu 
145                 150                 155                 160 


Val Cys Asn Pro Asn Val Tyr Ser Cys Ser Ile Pro Ala Thr Phe His 
                165                 170                 175     


Gln Glu Leu Ile His Met Pro Gln Leu Cys Thr Arg Ala Ser Ser Ser 
            180                 185                 190         


Glu Ile Pro Gly Arg Leu Leu Thr Thr Leu Gln Ser Ala Gln Gly Gln 
        195                 200                 205             


Lys Phe Leu His Phe Ala Lys Ser Asp Ser Phe Leu Asp Asp Ile Phe 
    210                 215                 220                 


Ala Ala Trp Met Ala Gln Arg Leu Lys Thr His Leu Leu Thr Glu Thr 
225                 230                 235                 240 


Trp Gln Arg Lys Arg Gln Glu Leu Pro Ser Asn Cys Ser Leu Pro Tyr 
                245                 250                 255     


His Val Tyr Asn Ile Lys Ala Ile Lys Leu Ser Arg His Ser Tyr Phe 
            260                 265                 270         


Ser Ser Tyr Gln Asp His Ala Lys Trp Cys Ile Ser Gln Lys Gly Thr 
        275                 280                 285             


Lys Asn Arg Trp Thr Cys Ile Gly Asp Leu Asn Arg Ser Pro His Gln 
    290                 295                 300                 


Ala Phe Arg Ser Gly Gly Phe Ile Cys Thr Gln Asn Trp Gln Ile Tyr 
305                 310                 315                 320 


Gln Ala Phe Gln Gly Leu Val Leu Tyr Tyr Glu Ser Cys Lys 
                325                 330                 


<210>  2742
<211>  431
<212>  PRT
<213>  Homo Sapiens

<400>  2742

Leu Pro Val Ala Pro Ala Gly Gly Arg Asn Pro Pro Pro Ala Ile Gly 
1               5                   10                  15      


Gln Phe Trp His Val Thr Asp Leu His Leu Asp Pro Thr Tyr His Ile 
            20                  25                  30          


Thr Asp Asp His Thr Lys Val Cys Ala Ser Ser Lys Gly Ala Asn Ala 
        35                  40                  45              


Ser Asn Pro Gly Pro Phe Gly Asp Val Leu Cys Asp Ser Pro Tyr Gln 
    50                  55                  60                  


Leu Ile Leu Ser Ala Phe Asp Phe Ile Lys Asn Ser Gly Gln Glu Ala 
65                  70                  75                  80  


Ser Phe Met Ile Trp Thr Gly Asp Ser Pro Pro His Val Pro Val Pro 
                85                  90                  95      


Glu Leu Ser Thr Asp Thr Val Ile Asn Val Ile Thr Asn Met Thr Thr 
            100                 105                 110         


Thr Ile Gln Ser Leu Phe Pro Asn Leu Gln Val Phe Pro Ala Leu Gly 
        115                 120                 125             


Asn His Asp Tyr Trp Pro Gln Asp Gln Leu Pro Val Val Thr Ser Lys 
    130                 135                 140                 


Val Tyr Asn Ala Val Ala Asn Leu Trp Lys Pro Trp Leu Asp Glu Glu 
145                 150                 155                 160 


Ala Ile Ser Thr Leu Arg Lys Gly Gly Phe Tyr Ser Gln Lys Val Thr 
                165                 170                 175     


Thr Asn Pro Asn Leu Arg Ile Ile Ser Leu Asn Thr Asn Leu Tyr Tyr 
            180                 185                 190         


Gly Pro Asn Ile Met Thr Leu Asn Lys Thr Asp Pro Ala Asn Gln Phe 
        195                 200                 205             


Glu Trp Leu Glu Ser Thr Leu Asn Asn Ser Gln Gln Asn Lys Glu Lys 
    210                 215                 220                 


Val Tyr Ile Ile Ala His Val Pro Val Gly Tyr Leu Pro Ser Ser Gln 
225                 230                 235                 240 


Asn Ile Thr Ala Met Arg Glu Tyr Tyr Asn Glu Lys Leu Ile Asp Ile 
                245                 250                 255     


Phe Gln Lys Tyr Ser Asp Val Ile Ala Gly Gln Phe Tyr Gly His Thr 
            260                 265                 270         


His Arg Asp Ser Ile Met Val Leu Ser Asp Lys Lys Gly Ser Pro Val 
        275                 280                 285             


Asn Ser Leu Phe Val Ala Pro Ala Val Thr Pro Val Lys Ser Val Leu 
    290                 295                 300                 


Glu Lys Gln Thr Asn Asn Pro Gly Ile Arg Leu Phe Gln Tyr Asp Pro 
305                 310                 315                 320 


Arg Asp Tyr Lys Leu Leu Asp Met Leu Gln Tyr Tyr Leu Asn Leu Thr 
                325                 330                 335     


Glu Ala Asn Leu Lys Gly Glu Ser Ile Trp Lys Leu Glu Tyr Ile Leu 
            340                 345                 350         


Thr Gln Thr Tyr Asp Ile Glu Asp Leu Gln Pro Glu Ser Leu Tyr Gly 
        355                 360                 365             


Leu Ala Lys Gln Phe Thr Ile Leu Asp Ser Lys Gln Phe Ile Lys Tyr 
    370                 375                 380                 


Tyr Asn Tyr Phe Phe Val Ser Tyr Asp Ser Ser Val Thr Cys Asp Lys 
385                 390                 395                 400 


Thr Cys Lys Ala Phe Gln Ile Cys Ala Ile Met Asn Leu Asp Asn Ile 
                405                 410                 415     


Ser Tyr Ala Asp Cys Leu Lys Gln Leu Tyr Ile Lys His Asn Tyr 
            420                 425                 430     


<210>  2743
<211>  203
<212>  PRT
<213>  Homo Sapiens

<400>  2743

Gln Val Phe Glu Ile Lys Met Asp Ala Ser Leu Gly Asn Leu Phe Ala 
1               5                   10                  15      


Arg Ser Ala Leu Asp Thr Ala Ala Arg Ser Thr Lys Pro Pro Arg Tyr 
            20                  25                  30          


Lys Cys Gly Ile Ser Lys Ala Cys Pro Glu Lys His Phe Ala Phe Lys 
        35                  40                  45              


Met Ala Ser Gly Ala Ala Asn Val Val Gly Pro Lys Ile Cys Leu Glu 
    50                  55                  60                  


Asp Asn Val Leu Met Ser Gly Val Lys Asn Asn Val Gly Arg Gly Ile 
65                  70                  75                  80  


Asn Val Ala Leu Ala Asn Gly Lys Thr Gly Glu Val Leu Asp Thr Lys 
                85                  90                  95      


Tyr Phe Asp Met Trp Gly Gly Asp Val Ala Pro Phe Ile Glu Phe Leu 
            100                 105                 110         


Lys Ala Ile Gln Asp Gly Thr Ile Val Leu Met Gly Thr Tyr Asp Asp 
        115                 120                 125             


Gly Ala Thr Lys Leu Asn Asp Glu Ala Arg Arg Leu Ile Ala Asp Leu 
    130                 135                 140                 


Gly Ser Thr Ser Ile Thr Asn Leu Gly Phe Arg Asp Asn Trp Val Phe 
145                 150                 155                 160 


Cys Gly Gly Lys Gly Ile Lys Thr Lys Ser Pro Phe Glu Gln His Ile 
                165                 170                 175     


Lys Asn Asn Lys Asp Thr Asn Lys Tyr Glu Gly Trp Pro Glu Val Val 
            180                 185                 190         


Glu Met Glu Gly Cys Ile Pro Gln Lys Gln Asp 
        195                 200             


<210>  2744
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  2744

Ser Val Cys Pro Leu Pro Pro Glu Pro Glu Asn Gly Gly Tyr Ile Cys 
1               5                   10                  15      


His Pro Arg Pro Cys Arg Asp Pro Leu Thr Ala Gly Ser Val Ile Glu 
            20                  25                  30          


Tyr Leu Cys Ala Glu Gly Tyr Met Leu Lys Gly Asp Tyr Lys Tyr Leu 
        35                  40                  45              


Thr Cys Lys Asn Gly Glu Trp Lys Pro Ala Met Glu Ile Ser Cys Arg 
    50                  55                  60                  


Leu Asn Glu Asp Lys Asp Thr His Thr Ser Leu Gly Val Pro Thr Leu 
65                  70                  75                  80  


Ser 
    


<210>  2745
<211>  636
<212>  PRT
<213>  Homo Sapiens

<400>  2745

Asn Ser Val Glu Arg Lys Ile Tyr Ile Pro Leu Asn Lys Thr Ala Pro 
1               5                   10                  15      


Cys Val Arg Leu Leu Asn Ala Thr His Gln Ile Gly Cys Gln Ser Ser 
            20                  25                  30          


Ile Ser Gly Asp Thr Gly Val Ile His Val Val Glu Lys Glu Glu Asp 
        35                  40                  45              


Leu Gln Trp Val Leu Thr Asp Gly Pro Asn Pro Pro Tyr Met Val Leu 
    50                  55                  60                  


Leu Glu Ser Lys His Phe Thr Arg Asp Leu Met Glu Lys Leu Lys Gly 
65                  70                  75                  80  


Arg Thr Ser Arg Ile Ala Gly Leu Ala Val Ser Leu Thr Lys Pro Ser 
                85                  90                  95      


Pro Ala Ser Gly Phe Ser Pro Ser Val Gln Cys Pro Asn Asp Gly Phe 
            100                 105                 110         


Gly Val Tyr Ser Asn Ser Tyr Gly Pro Glu Phe Ala His Cys Arg Glu 
        115                 120                 125             


Ile Gln Trp Asn Ser Leu Gly Asn Gly Leu Ala Tyr Glu Asp Phe Ser 
    130                 135                 140                 


Phe Pro Ile Phe Leu Leu Glu Asp Glu Asn Glu Thr Lys Val Ile Lys 
145                 150                 155                 160 


Gln Cys Tyr Gln Asp His Asn Leu Ser Gln Asn Gly Ser Ala Pro Thr 
                165                 170                 175     


Phe Pro Leu Cys Ala Met Gln Leu Phe Ser His Met His Ala Val Ile 
            180                 185                 190         


Ser Thr Ala Thr Cys Met Arg Arg Ser Ser Ile Gln Ser Thr Phe Ser 
        195                 200                 205             


Ile Asn Pro Glu Ile Val Cys Asp Pro Leu Ser Asp Tyr Asn Val Trp 
    210                 215                 220                 


Ser Met Leu Lys Pro Ile Asn Thr Thr Gly Thr Leu Lys Pro Asp Asp 
225                 230                 235                 240 


Arg Val Val Val Ala Ala Thr Arg Leu Asp Ser Arg Ser Phe Phe Trp 
                245                 250                 255     


Asn Val Ala Pro Gly Ala Glu Ser Ala Val Ala Ser Phe Val Thr Gln 
            260                 265                 270         


Leu Ala Ala Ala Glu Ala Leu Gln Lys Ala Pro Asp Val Thr Thr Leu 
        275                 280                 285             


Pro Arg Asn Val Met Phe Val Phe Phe Gln Gly Glu Thr Phe Asp Tyr 
    290                 295                 300                 


Ile Gly Ser Ser Arg Met Val Tyr Asp Met Glu Lys Gly Lys Phe Pro 
305                 310                 315                 320 


Val Gln Leu Glu Asn Val Asp Ser Phe Val Glu Leu Gly Gln Val Ala 
                325                 330                 335     


Leu Arg Thr Ser Leu Glu Leu Trp Met His Thr Asp Pro Val Ser Gln 
            340                 345                 350         


Lys Asn Glu Ser Val Arg Asn Gln Val Glu Asp Leu Leu Ala Thr Leu 
        355                 360                 365             


Glu Lys Ser Gly Ala Gly Val Pro Ala Val Ile Leu Arg Arg Pro Asn 
    370                 375                 380                 


Gln Ser Gln Pro Leu Pro Pro Ser Ser Leu Gln Arg Phe Leu Arg Ala 
385                 390                 395                 400 


Arg Asn Ile Ser Gly Val Val Leu Ala Asp His Ser Gly Ala Phe His 
                405                 410                 415     


Asn Lys Tyr Tyr Gln Ser Ile Tyr Asp Thr Ala Glu Asn Ile Asn Val 
            420                 425                 430         


Ser Tyr Pro Glu Trp Leu Ser Pro Glu Glu Asp Leu Asn Phe Val Thr 
        435                 440                 445             


Asp Thr Ala Lys Ala Leu Ala Asp Val Ala Thr Val Leu Gly Arg Ala 
    450                 455                 460                 


Leu Tyr Glu Leu Ala Gly Gly Thr Asn Phe Ser Asp Thr Val Gln Ala 
465                 470                 475                 480 


Asp Pro Gln Thr Val Thr Arg Leu Leu Tyr Gly Phe Leu Ile Lys Ala 
                485                 490                 495     


Asn Asn Ser Trp Phe Gln Ser Ile Leu Arg Gln Asp Leu Arg Ser Tyr 
            500                 505                 510         


Leu Gly Asp Gly Pro Leu Gln His Tyr Ile Ala Val Ser Ser Pro Thr 
        515                 520                 525             


Asn Thr Thr Tyr Val Val Gln Tyr Ala Leu Ala Asn Leu Thr Gly Thr 
    530                 535                 540                 


Val Val Asn Leu Thr Arg Glu Gln Cys Gln Asp Pro Ser Lys Val Pro 
545                 550                 555                 560 


Ser Glu Asn Lys Asp Leu Tyr Glu Tyr Ser Trp Val Gln Gly Pro Leu 
                565                 570                 575     


His Ser Asn Glu Thr Asp Arg Leu Pro Arg Cys Val Arg Ser Thr Ala 
            580                 585                 590         


Arg Leu Ala Arg Ala Leu Ser Pro Ala Phe Glu Leu Ser Gln Trp Ser 
        595                 600                 605             


Ser Thr Glu Tyr Ser Thr Trp Thr Glu Ser Arg Trp Lys Asp Ile His 
    610                 615                 620                 


Ala Arg Ile Phe Leu Ile Ala Ser Lys Glu Leu Glu 
625                 630                 635     


<210>  2746
<211>  402
<212>  PRT
<213>  Homo Sapiens

<400>  2746

Glu Gly Asp Ala Lys Gly Leu Lys Glu Gly Glu Thr Pro Gly Asn Phe 
1               5                   10                  15      


Met Glu Asp Glu Gln Trp Leu Ser Ser Ile Ser Gln Tyr Ser Gly Lys 
            20                  25                  30          


Ile Lys His Trp Asn Arg Phe Arg Asp Glu Val Glu Asp Asp Tyr Ile 
        35                  40                  45              


Lys Ser Trp Glu Asp Asn Gln Gln Gly Asp Glu Ala Leu Asp Thr Thr 
    50                  55                  60                  


Lys Asp Pro Cys Gln Lys Val Lys Cys Ser Arg His Lys Val Cys Ile 
65                  70                  75                  80  


Ala Gln Gly Tyr Gln Arg Ala Met Cys Ile Ser Arg Lys Lys Leu Glu 
                85                  90                  95      


His Arg Ile Lys Gln Pro Thr Val Lys Leu His Gly Asn Lys Asp Ser 
            100                 105                 110         


Ile Cys Lys Pro Cys His Met Ala Gln Leu Ala Ser Val Cys Gly Ser 
        115                 120                 125             


Asp Gly His Thr Tyr Ser Ser Val Cys Lys Leu Glu Gln Gln Ala Cys 
    130                 135                 140                 


Leu Ser Ser Lys Gln Leu Ala Val Arg Cys Glu Gly Pro Cys Pro Cys 
145                 150                 155                 160 


Pro Thr Glu Gln Ala Ala Thr Ser Thr Ala Asp Gly Lys Pro Glu Thr 
                165                 170                 175     


Cys Thr Gly Gln Asp Leu Ala Asp Leu Gly Asp Arg Leu Arg Asp Trp 
            180                 185                 190         


Phe Gln Leu Leu His Glu Asn Ser Lys Gln Asn Gly Ser Ala Ser Ser 
        195                 200                 205             


Val Ala Gly Pro Ala Ser Gly Leu Asp Lys Ser Leu Gly Ala Ser Cys 
    210                 215                 220                 


Lys Asp Ser Ile Gly Trp Met Phe Ser Lys Leu Asp Thr Ser Ala Asp 
225                 230                 235                 240 


Leu Phe Leu Asp Gln Thr Glu Leu Ala Ala Ile Asn Leu Asp Lys Tyr 
                245                 250                 255     


Glu Val Cys Ile Arg Pro Phe Phe Asn Ser Cys Asp Thr Tyr Lys Asp 
            260                 265                 270         


Gly Arg Val Ser Thr Ala Glu Trp Cys Phe Cys Phe Trp Arg Glu Lys 
        275                 280                 285             


Pro Pro Cys Leu Ala Glu Leu Glu Arg Ile Gln Ile Gln Glu Ala Ala 
    290                 295                 300                 


Lys Lys Lys Pro Gly Ile Phe Ile Pro Ser Cys Asp Glu Asp Gly Tyr 
305                 310                 315                 320 


Tyr Arg Lys Met Gln Cys Asp Gln Ser Ser Gly Asp Cys Trp Cys Val 
                325                 330                 335     


Asp Gln Leu Gly Leu Glu Leu Thr Gly Thr Arg Thr His Gly Ser Pro 
            340                 345                 350         


Asp Cys Asp Asp Ile Val Gly Phe Ser Gly Asp Phe Gly Ser Gly Val 
        355                 360                 365             


Gly Trp Glu Asp Glu Glu Glu Lys Glu Thr Glu Glu Ala Gly Glu Glu 
    370                 375                 380                 


Ala Glu Glu Glu Glu Gly Glu Ala Gly Glu Ala Asp Asp Gly Gly Tyr 
385                 390                 395                 400 


Ile Trp 
        


<210>  2747
<211>  233
<212>  PRT
<213>  Homo Sapiens

<400>  2747

Lys Val Met Asn Phe Thr Ile Asp Gly Met Gly Asn Leu Arg Ile Thr 
1               5                   10                  15      


Glu Lys Gly Leu Lys Leu Glu Gly Asp Ser Glu Phe Leu Gln Pro Leu 
            20                  25                  30          


Tyr Ala Lys Glu Ile Gln Ser Arg Pro Gly Asn Ala Leu Tyr Phe Lys 
        35                  40                  45              


Ser Ala Arg Asn Val Thr Val Asn Ile Leu Asn Asp Gln Thr Lys Val 
    50                  55                  60                  


Leu Thr Gln Leu Ile Thr Gly Pro Lys Ala Val Glu Ala Tyr Gly Lys 
65                  70                  75                  80  


Lys Phe Glu Val Lys Thr Val Ser Gly Lys Leu Leu Phe Ser Ala Asp 
                85                  90                  95      


Asn Asn Glu Val Val Val Gly Ala Glu Arg Leu Arg Val Leu Gly Ala 
            100                 105                 110         


Glu Gly Thr Val Phe Pro Lys Ser Ile Glu Thr Pro Asn Val Arg Ala 
        115                 120                 125             


Asp Pro Phe Lys Glu Leu Arg Leu Glu Ser Pro Thr Arg Ser Leu Val 
    130                 135                 140                 


Met Glu Ala Pro Lys Gly Val Glu Ile Asn Ala Glu Ala Gly Asn Met 
145                 150                 155                 160 


Glu Ala Thr Cys Arg Thr Glu Leu Arg Leu Glu Ser Lys Asp Gly Glu 
                165                 170                 175     


Ile Lys Leu Asp Ala Ala Lys Ile Arg Leu Pro Arg Leu Pro His Gly 
            180                 185                 190         


Ser Tyr Thr Pro Thr Gly Thr Arg Gln Lys Val Phe Glu Ile Cys Val 
        195                 200                 205             


Cys Ala Asn Gly Arg Leu Phe Leu Ser Gln Ala Gly Ala Gly Ser Thr 
    210                 215                 220                 


Cys Gln Ile Asn Thr Ser Val Cys Leu 
225                 230             


<210>  2748
<211>  293
<212>  PRT
<213>  Homo Sapiens

<400>  2748

Ala Ala Cys Glu Pro Val Arg Ile Pro Leu Cys Lys Ser Leu Pro Trp 
1               5                   10                  15      


Asn Met Thr Lys Met Pro Asn His Leu His His Ser Thr Gln Ala Asn 
            20                  25                  30          


Ala Ile Leu Ala Ile Glu Gln Phe Glu Gly Leu Leu Gly Thr His Cys 
        35                  40                  45              


Ser Pro Asp Leu Leu Phe Phe Leu Cys Ala Met Tyr Ala Pro Ile Cys 
    50                  55                  60                  


Thr Ile Asp Phe Gln His Glu Pro Ile Lys Pro Cys Lys Ser Val Cys 
65                  70                  75                  80  


Glu Arg Ala Arg Gln Gly Cys Glu Pro Ile Leu Ile Lys Tyr Arg His 
                85                  90                  95      


Ser Trp Pro Glu Asn Leu Ala Cys Glu Glu Leu Pro Val Tyr Asp Arg 
            100                 105                 110         


Gly Val Cys Ile Ser Pro Glu Ala Ile Val Thr Ala Asp Gly Ala Asp 
        115                 120                 125             


Phe Pro Met Asp Ser Ser Asn Gly Asn Cys Arg Gly Ala Ser Ser Glu 
    130                 135                 140                 


Arg Cys Lys Cys Lys Pro Ile Arg Ala Thr Gln Lys Thr Tyr Phe Arg 
145                 150                 155                 160 


Asn Asn Tyr Asn Tyr Val Ile Arg Ala Lys Val Lys Glu Ile Lys Thr 
                165                 170                 175     


Lys Cys His Asp Val Thr Ala Val Val Glu Val Lys Glu Ile Leu Lys 
            180                 185                 190         


Ser Ser Leu Val Asn Ile Pro Arg Asp Thr Val Asn Leu Tyr Thr Ser 
        195                 200                 205             


Ser Gly Cys Leu Cys Pro Pro Leu Asn Val Asn Glu Glu Tyr Ile Ile 
    210                 215                 220                 


Met Gly Tyr Glu Asp Glu Glu Arg Ser Arg Leu Leu Leu Val Glu Gly 
225                 230                 235                 240 


Ser Ile Ala Glu Lys Trp Lys Asp Arg Leu Gly Lys Lys Val Lys Arg 
                245                 250                 255     


Trp Asp Met Lys Leu Arg His Leu Gly Leu Ser Lys Ser Asp Ser Ser 
            260                 265                 270         


Asn Ser Asp Ser Thr Gln Ser Gln Lys Ser Gly Arg Asn Ser Asn Pro 
        275                 280                 285             


Arg Gln Ala Arg Asn 
    290             


<210>  2749
<211>  295
<212>  PRT
<213>  Homo Sapiens

<400>  2749

Leu Pro Ala Ser Asn Ala Leu Val Phe Ile Thr Gly Cys Asp Ser Gly 
1               5                   10                  15      


Phe Gly Arg Leu Leu Ala Leu Gln Leu Asp Gln Arg Gly Phe Arg Val 
            20                  25                  30          


Leu Ala Ser Cys Leu Thr Pro Ser Gly Ala Glu Asp Leu Gln Arg Val 
        35                  40                  45              


Ala Ser Ser Arg Leu His Thr Thr Leu Leu Asp Ile Thr Asp Pro Gln 
    50                  55                  60                  


Ser Val Gln Gln Ala Ala Lys Trp Val Glu Met His Val Lys Glu Ala 
65                  70                  75                  80  


Gly Leu Phe Gly Leu Val Asn Asn Ala Gly Val Ala Gly Ile Ile Gly 
                85                  90                  95      


Pro Thr Pro Trp Leu Thr Arg Asp Asp Phe Gln Arg Val Leu Asn Val 
            100                 105                 110         


Asn Thr Met Gly Pro Ile Gly Val Thr Leu Ala Leu Leu Pro Leu Leu 
        115                 120                 125             


Gln Gln Ala Arg Gly Arg Val Ile Asn Ile Thr Ser Val Leu Gly Arg 
    130                 135                 140                 


Leu Ala Ala Asn Gly Gly Gly Tyr Cys Val Ser Lys Phe Gly Leu Glu 
145                 150                 155                 160 


Ala Phe Ser Asp Ser Leu Arg Arg Asp Val Ala His Phe Gly Ile Arg 
                165                 170                 175     


Val Ser Ile Val Glu Pro Gly Phe Phe Arg Thr Pro Val Thr Asn Leu 
            180                 185                 190         


Glu Ser Leu Glu Lys Thr Leu Gln Ala Cys Trp Ala Arg Leu Pro Pro 
        195                 200                 205             


Ala Thr Gln Ala His Tyr Gly Gly Ala Phe Leu Thr Lys Tyr Leu Lys 
    210                 215                 220                 


Met Gln Gln Arg Ile Met Asn Leu Ile Cys Asp Pro Asp Leu Thr Lys 
225                 230                 235                 240 


Val Ser Arg Cys Leu Glu His Ala Leu Thr Ala Arg His Pro Arg Thr 
                245                 250                 255     


Arg Tyr Ser Pro Gly Trp Asp Ala Lys Leu Leu Trp Leu Pro Ala Ser 
            260                 265                 270         


Tyr Leu Pro Ala Ser Leu Val Asp Ala Val Leu Thr Trp Val Leu Pro 
        275                 280                 285             


Lys Pro Ala Gln Ala Val Tyr 
    290                 295 


<210>  2750
<211>  294
<212>  PRT
<213>  Homo Sapiens

<400>  2750

Arg Pro His Gly Asp Thr Ala Lys Lys Pro Ile Ile Gly Ile Leu Met 
1               5                   10                  15      


Gln Lys Cys Arg Asn Lys Val Met Lys Asn Tyr Gly Arg Tyr Tyr Ile 
            20                  25                  30          


Ala Ala Ser Tyr Val Lys Tyr Leu Glu Ser Ala Gly Ala Arg Val Val 
        35                  40                  45              


Pro Val Arg Leu Asp Leu Thr Glu Lys Asp Tyr Glu Ile Leu Phe Lys 
    50                  55                  60                  


Ser Ile Asn Gly Ile Leu Phe Pro Gly Gly Ser Val Asp Leu Arg Arg 
65                  70                  75                  80  


Ser Asp Tyr Ala Lys Val Ala Lys Ile Phe Tyr Asn Leu Ser Ile Gln 
                85                  90                  95      


Ser Phe Asp Asp Gly Asp Tyr Phe Pro Val Trp Gly Thr Cys Leu Gly 
            100                 105                 110         


Phe Glu Glu Leu Ser Leu Leu Ile Ser Gly Glu Cys Leu Leu Thr Ala 
        115                 120                 125             


Thr Asp Thr Val Asp Val Ala Met Pro Leu Asn Phe Thr Gly Gly Gln 
    130                 135                 140                 


Leu His Ser Arg Met Phe Gln Asn Phe Pro Thr Glu Leu Leu Leu Ser 
145                 150                 155                 160 


Leu Ala Val Glu Pro Leu Thr Ala Asn Phe His Lys Trp Ser Leu Ser 
                165                 170                 175     


Val Lys Asn Phe Thr Met Asn Glu Lys Leu Lys Lys Phe Phe Asn Val 
            180                 185                 190         


Leu Thr Thr Asn Thr Asp Gly Lys Ile Glu Phe Ile Ser Thr Met Glu 
        195                 200                 205             


Gly Tyr Lys Tyr Pro Val Tyr Gly Val Gln Trp His Pro Glu Lys Ala 
    210                 215                 220                 


Pro Tyr Glu Trp Lys Asn Leu Asp Gly Ile Ser His Ala Pro Asn Ala 
225                 230                 235                 240 


Val Lys Thr Ala Phe Tyr Leu Ala Glu Phe Phe Val Asn Glu Ala Arg 
                245                 250                 255     


Lys Asn Asn His His Phe Lys Ser Glu Ser Glu Glu Glu Lys Ala Leu 
            260                 265                 270         


Ile Tyr Gln Phe Ser Pro Ile Tyr Thr Gly Asn Ile Ser Ser Phe Gln 
        275                 280                 285             


Gln Cys Tyr Ile Phe Asp 
    290                 


<210>  2751
<211>  279
<212>  PRT
<213>  Homo Sapiens

<400>  2751

Ala Leu Arg Ile Gly Ala Phe Asn Ile Gln Ser Phe Gly Asp Ser Lys 
1               5                   10                  15      


Val Ser Asp Pro Ala Cys Gly Ser Ile Ile Ala Lys Ile Leu Ala Gly 
            20                  25                  30          


Tyr Asp Leu Ala Leu Val Gln Glu Val Arg Asp Pro Asp Leu Ser Ala 
        35                  40                  45              


Val Ser Ala Leu Met Glu Gln Ile Asn Ser Val Ser Glu His Glu Tyr 
    50                  55                  60                  


Ser Phe Val Ser Ser Gln Pro Leu Gly Arg Asp Gln Tyr Lys Glu Met 
65                  70                  75                  80  


Tyr Leu Phe Val Tyr Arg Lys Asp Ala Val Ser Val Val Asp Thr Tyr 
                85                  90                  95      


Leu Tyr Pro Asp Pro Glu Asp Val Phe Ser Arg Glu Pro Phe Val Val 
            100                 105                 110         


Lys Phe Ser Ala Pro Gly Thr Gly Glu Arg Ala Pro Pro Leu Pro Ser 
        115                 120                 125             


Arg Arg Ala Leu Thr Pro Pro Pro Leu Pro Ala Ala Ala Gln Asn Leu 
    130                 135                 140                 


Val Leu Ile Pro Leu His Ala Ala Pro His Gln Ala Val Ala Glu Ile 
145                 150                 155                 160 


Asp Ala Leu Tyr Asp Val Tyr Leu Asp Val Ile Asp Lys Trp Gly Thr 
                165                 170                 175     


Asp Asp Met Leu Phe Leu Gly Asp Phe Asn Ala Asp Cys Ser Tyr Val 
            180                 185                 190         


Arg Ala Gln Asp Trp Ala Ala Ile Arg Leu Arg Ser Ser Glu Val Phe 
        195                 200                 205             


Lys Trp Leu Ile Pro Asp Ser Ala Asp Thr Thr Val Gly Asn Ser Asp 
    210                 215                 220                 


Cys Ala Tyr Asp Arg Ile Val Ala Cys Gly Ala Arg Leu Arg Arg Ser 
225                 230                 235                 240 


Leu Lys Pro Gln Ser Ala Thr Val His Asp Phe Gln Glu Glu Phe Gly 
                245                 250                 255     


Leu Asp Gln Thr Gln Ala Leu Ala Ile Ser Asp His Phe Pro Val Glu 
            260                 265                 270         


Val Thr Leu Lys Phe His Arg 
        275                 


<210>  2752
<211>  223
<212>  PRT
<213>  Homo Sapiens

<400>  2752

Leu Val His Gly Gly Pro Cys Asp Lys Thr Ser His Pro Tyr Gln Ala 
1               5                   10                  15      


Ala Leu Tyr Thr Ser Gly His Leu Leu Cys Gly Gly Val Leu Ile His 
            20                  25                  30          


Pro Leu Trp Val Leu Thr Ala Ala His Cys Lys Lys Pro Asn Leu Gln 
        35                  40                  45              


Val Phe Leu Gly Lys His Asn Leu Arg Gln Arg Glu Ser Ser Gln Glu 
    50                  55                  60                  


Gln Ser Ser Val Val Arg Ala Val Ile His Pro Asp Tyr Asp Ala Ala 
65                  70                  75                  80  


Ser His Asp Gln Asp Ile Met Leu Leu Arg Leu Ala Arg Pro Ala Lys 
                85                  90                  95      


Leu Ser Glu Leu Ile Gln Pro Leu Pro Leu Glu Arg Asp Cys Ser Ala 
            100                 105                 110         


Asn Thr Thr Ser Cys His Ile Leu Gly Trp Gly Lys Thr Ala Asp Gly 
        115                 120                 125             


Asp Phe Pro Asp Thr Ile Gln Cys Ala Tyr Ile His Leu Val Ser Arg 
    130                 135                 140                 


Glu Glu Cys Glu His Ala Tyr Pro Gly Gln Ile Thr Gln Asn Met Leu 
145                 150                 155                 160 


Cys Ala Gly Asp Glu Lys Tyr Gly Lys Asp Ser Cys Gln Gly Asp Ser 
                165                 170                 175     


Gly Gly Pro Leu Val Cys Gly Asp His Leu Arg Gly Leu Val Ser Trp 
            180                 185                 190         


Gly Asn Ile Pro Cys Gly Ser Lys Glu Lys Pro Gly Val Tyr Thr Asn 
        195                 200                 205             


Val Cys Arg Tyr Thr Asn Trp Ile Gln Lys Thr Ile Gln Ala Lys 
    210                 215                 220             


<210>  2753
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  2753

Tyr Pro Pro Ser Glu Gln Thr Met Arg Val Leu Pro Ser Ser Ala Ala 
1               5                   10                  15      


Arg Cys Val Ala Leu Ser Val Asn Ala Ser Gly Leu Leu Asp Pro Ala 
            20                  25                  30          


Leu Leu Pro Ala Asn Asp Ser Ser Arg Ala Pro Ser Ser Gly Met Asp 
        35                  40                  45              


Ala Ser Arg Pro Ala Leu Ala Asp Ser Phe Tyr Ala 
    50                  55                  60  


<210>  2754
<211>  565
<212>  PRT
<213>  Homo Sapiens

<400>  2754

Ala Ala Pro Ser Ser Val Pro Arg Gly Arg Gln Leu Pro Gly Arg Leu 
1               5                   10                  15      


Gly Cys Leu Leu Glu Glu Gly Leu Cys Gly Ala Ser Glu Ala Cys Val 
            20                  25                  30          


Asn Asp Gly Val Phe Gly Arg Cys Gln Lys Val Pro Ala Met Asp Phe 
        35                  40                  45              


Tyr Arg Tyr Glu Val Ser Pro Val Ala Leu Gln Arg Leu Arg Val Ala 
    50                  55                  60                  


Leu Gln Lys Leu Ser Gly Thr Gly Phe Thr Trp Gln Asp Asp Tyr Thr 
65                  70                  75                  80  


Gln Tyr Val Met Asp Gln Glu Leu Ala Asp Leu Pro Lys Thr Tyr Leu 
                85                  90                  95      


Arg Arg Pro Glu Ala Ser Ser Pro Ala Arg Pro Ser Lys His Ser Val 
            100                 105                 110         


Gly Ser Glu Arg Arg Tyr Ser Arg Glu Gly Gly Ala Ala Leu Ala Asn 
        115                 120                 125             


Ala Leu Arg Arg His Leu Pro Phe Leu Glu Ala Leu Ser Gln Ala Pro 
    130                 135                 140                 


Ala Ser Asp Val Leu Ala Arg Thr His Thr Ala Gln Asp Arg Pro Pro 
145                 150                 155                 160 


Ala Glu Gly Asp Asp Arg Phe Ser Glu Ser Ile Leu Thr Tyr Val Ala 
                165                 170                 175     


His Thr Ser Ala Leu Thr Tyr Pro Pro Gly Pro Arg Thr Gln Leu Arg 
            180                 185                 190         


Glu Asp Leu Leu Pro Arg Thr Leu Gly Gln Leu Gln Pro Asp Glu Leu 
        195                 200                 205             


Ser Pro Lys Val Asp Ser Gly Val Asp Arg His His Leu Met Ala Ala 
    210                 215                 220                 


Leu Ser Ala Tyr Ala Ala Gln Arg Pro Pro Ala Pro Pro Gly Glu Gly 
225                 230                 235                 240 


Ser Leu Glu Pro Gln Tyr Leu Leu Arg Ala Pro Ser Arg Met Pro Arg 
                245                 250                 255     


Pro Leu Leu Ala Pro Ala Ala Pro Gln Lys Trp Pro Ser Pro Leu Gly 
            260                 265                 270         


Asp Ser Glu Asp Pro Ser Ser Thr Gly Asp Gly Ala Arg Ile His Thr 
        275                 280                 285             


Leu Leu Lys Asp Leu Gln Arg Gln Pro Ala Glu Val Arg Gly Leu Ser 
    290                 295                 300                 


Gly Leu Glu Leu Asp Gly Met Ala Glu Leu Met Ala Gly Leu Met Gln 
305                 310                 315                 320 


Gly Val Asp His Gly Val Ala Arg Gly Ser Pro Gly Arg Ala Ala Leu 
                325                 330                 335     


Gly Glu Ser Gly Glu Gln Ala Asp Gly Pro Lys Ala Thr Leu Arg Gly 
            340                 345                 350         


Asp Ser Phe Pro Asp Asp Gly Val Gln Asp Asp Asp Asp Arg Leu Tyr 
        355                 360                 365             


Gln Glu Val His Arg Leu Ser Ala Thr Leu Gly Gly Leu Leu Gln Asp 
    370                 375                 380                 


His Gly Ser Arg Leu Leu Pro Gly Ala Leu Pro Phe Ala Arg Pro Leu 
385                 390                 395                 400 


Asp Met Glu Arg Lys Lys Ser Glu His Pro Glu Ser Ser Leu Ser Ser 
                405                 410                 415     


Glu Glu Glu Thr Ala Gly Val Glu Asn Val Lys Ser Gln Thr Tyr Ser 
            420                 425                 430         


Lys Asp Leu Leu Gly Gln Gln Pro His Ser Glu Pro Gly Ala Ala Ala 
        435                 440                 445             


Phe Gly Glu Leu Gln Asn Gln Met Pro Gly Pro Ser Lys Glu Glu Gln 
    450                 455                 460                 


Ser Leu Pro Ala Gly Ala Gln Glu Ala Leu Ser Asp Gly Leu Gln Leu 
465                 470                 475                 480 


Glu Val Gln Pro Ser Glu Glu Glu Ala Arg Gly Tyr Ile Val Thr Asp 
                485                 490                 495     


Arg Glu Val Leu Gly Pro Ala Val Thr Phe Lys Val Ser Ala Asn Val 
            500                 505                 510         


Gln Asn Val Thr Thr Glu Asp Val Glu Lys Ala Thr Val Asp Asn Lys 
        515                 520                 525             


Asp Lys Leu Glu Glu Thr Ser Gly Leu Lys Ile Leu Gln Thr Gly Val 
    530                 535                 540                 


Gly Ser Lys Ser Lys Leu Lys Phe Leu Pro Pro Gln Ala Glu Gln Glu 
545                 550                 555                 560 


Asp Ser Thr Lys Phe 
                565 


<210>  2755
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2755

Phe Phe Met Gly Cys Ser Thr Pro Thr Val Ala Glu Val Tyr Pro Pro 
1               5                   10                  15      


Ser Thr Ser Ser Ser Ile His Pro Gln Ser Pro Ala Cys Arg Arg Asp 
            20                  25                  30          


Cys Ser Cys Pro Asp Ser Ile Phe His Pro Val Cys Gly Asp Asn Gly 
        35                  40                  45              


Ile Glu Tyr Leu Ser Pro Cys His Ala Gly Cys Ser Asn Ile Asn Met 
    50                  55                  60                  


Ser Ser Ala Thr Ser Lys Gln Leu Ile Tyr Leu Asn Cys Ser Cys Val 
65                  70                  75                  80  


Thr Gly Gly Ser Ala Ser Ala Lys Thr Gly Ser Cys Pro Val Pro Cys 
                85                  90                  95      


Ala His Phe Leu Leu Pro Ala 
            100             


<210>  2756
<211>  80
<212>  PRT
<213>  Homo Sapiens

<400>  2756

Met Asp Ser Gly Thr Glu Glu Tyr Glu Leu Asn Gly Gly Leu Pro Pro 
1               5                   10                  15      


Gly Thr Pro Gly Ser Pro Asp Ala Ser Pro Ala Arg Trp Gly Trp Arg 
            20                  25                  30          


His Gly Pro Ile Asn Val Asn His Tyr Ala Ser Lys Lys Ser Ala Ala 
        35                  40                  45              


Glu Ser Met Leu Asp Ile Ala Leu Leu Met Ala Asn Ala Ser Gln Leu 
    50                  55                  60                  


Lys Ala Val Val Glu Gln Gly Pro Ser Phe Ala Phe Tyr Val Pro Leu 
65                  70                  75                  80  


<210>  2757
<211>  239
<212>  PRT
<213>  Homo Sapiens

<400>  2757

Ser Glu Val Ala Ile Lys Ile Asp Phe Asp Phe Ala Pro Gly Ser Phe 
1               5                   10                  15      


Asp Asp Gln Tyr Gln Gly Cys Ser Lys Gln Val Met Glu Lys Leu Thr 
            20                  25                  30          


Gln Gly Asp Tyr Phe Thr Lys Asp Ile Glu Ala Gln Lys Asn Tyr Phe 
        35                  40                  45              


Arg Met Trp Gln Lys Ala His Leu Ala Trp Leu Asn Gln Gly Lys Val 
    50                  55                  60                  


Leu Pro Gln Asn Met Thr Thr Thr His Ala Val Ala Ile Leu Phe Tyr 
65                  70                  75                  80  


Thr Leu Asn Ser Asn Val His Ser Asp Phe Thr Arg Ala Met Ala Ser 
                85                  90                  95      


Val Ala Arg Thr Pro Gln Gln Tyr Glu Arg Ser Phe His Phe Lys Tyr 
            100                 105                 110         


Leu His Tyr Tyr Leu Thr Ser Ala Ile Gln Leu Leu Arg Lys Asp Ser 
        115                 120                 125             


Ile Met Glu Asn Gly Thr Leu Cys Tyr Glu Val His Tyr Arg Thr Lys 
    130                 135                 140                 


Asp Val His Phe Asn Ala Tyr Thr Gly Ala Thr Ile Arg Phe Gly Gln 
145                 150                 155                 160 


Phe Leu Ser Thr Ser Leu Leu Lys Glu Glu Ala Gln Glu Phe Gly Asn 
                165                 170                 175     


Gln Thr Leu Phe Thr Ile Phe Thr Cys Leu Gly Ala Pro Val Gln Tyr 
            180                 185                 190         


Phe Ser Leu Lys Lys Glu Val Leu Ile Pro Pro Tyr Glu Leu Phe Lys 
        195                 200                 205             


Val Ile Asn Met Ser Tyr His Pro Arg Gly Asn Trp Leu Gln Leu Arg 
    210                 215                 220                 


Ser Thr Gly Asn Leu Ser Thr Tyr Asn Cys Gln Leu Leu Lys Ala 
225                 230                 235                 


<210>  2758
<211>  268
<212>  PRT
<213>  Homo Sapiens

<400>  2758

Lys Lys Gly Tyr Gln Asp Val Asp Thr Ser Leu Gln Ser Ala Val Ile 
1               5                   10                  15      


Thr Lys Val Lys Gly Val Ala Phe Thr Asn Thr Ser Asp Leu Gly Gln 
            20                  25                  30          


Arg Ile Trp Asp Val Ala Asp Tyr Val Ile Pro Ala Gln Gly Glu Asn 
        35                  40                  45              


Val Phe Phe Val Val Thr Asn Leu Ile Val Thr Pro Asn Gln Arg Gln 
    50                  55                  60                  


Asn Val Cys Ala Glu Asn Glu Gly Ile Pro Asp Gly Ala Cys Ser Lys 
65                  70                  75                  80  


Asp Ser Asp Cys His Ala Gly Glu Ala Val Thr Ala Gly Asn Gly Val 
                85                  90                  95      


Lys Thr Gly Arg Cys Leu Arg Arg Glu Asn Leu Ala Arg Gly Thr Cys 
            100                 105                 110         


Glu Ile Phe Ala Trp Cys Pro Leu Glu Thr Ser Ser Arg Pro Glu Glu 
        115                 120                 125             


Pro Phe Leu Lys Glu Ala Glu Asp Phe Thr Ile Phe Ile Lys Asn His 
    130                 135                 140                 


Ile Arg Phe Pro Lys Phe Asn Phe Ser Lys Ser Asn Val Met Asp Val 
145                 150                 155                 160 


Lys Asp Arg Ser Phe Leu Lys Ser Cys His Phe Gly Pro Lys Asn His 
                165                 170                 175     


Tyr Cys Pro Ile Phe Arg Leu Gly Ser Val Ile Arg Trp Ala Gly Ser 
            180                 185                 190         


Asp Phe Gln Asp Ile Ala Leu Glu Gly Gly Val Ile Gly Ile Asn Ile 
        195                 200                 205             


Glu Trp Asn Cys Asp Leu Asp Lys Ala Ala Ser Glu Cys His Pro His 
    210                 215                 220                 


Tyr Ser Phe Ser Arg Leu Asp Asn Lys Leu Ser Lys Ser Val Ser Ser 
225                 230                 235                 240 


Gly Tyr Asn Phe Arg Phe Ala Arg Tyr Tyr Arg Asp Ala Ala Gly Val 
                245                 250                 255     


Glu Phe Arg Thr Leu Met Lys Ala Tyr Gly Ile Arg 
            260                 265             


<210>  2759
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2759

Trp Pro Lys Arg Leu Thr Lys Ala His Trp Phe Glu Ile Gln His Ile 
1               5                   10                  15      


Gln Pro Ser Pro Leu Gln Cys Asn Arg Ala Met Ser Gly Ile Asn Asn 
            20                  25                  30          


Tyr Thr Gln His Cys Lys His Gln Asn Thr Phe Leu His Asp Ser Phe 
        35                  40                  45              


Gln Asn Val Ala Ala Val Cys Asp Leu Leu Ser Ile Val Cys Lys Asn 
    50                  55                  60                  


Arg Arg His Asn Cys His Gln Ser Ser Lys Pro Val Asn Met Thr Asp 
65                  70                  75                  80  


Cys Arg Leu Thr Ser Gly Lys Tyr Pro Gln Cys Arg Tyr Ser Ala Ala 
                85                  90                  95      


Ala Gln Tyr Lys Phe Phe Ile Val Ala Cys Asp Pro Pro Gln Lys Ser 
            100                 105                 110         


Asp Pro Pro Tyr Lys Leu Val Pro Val His Leu Asp Ser Ile Leu 
        115                 120                 125         


<210>  2760
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  2760

Trp Ser Val Asn Asn Phe Leu Met Thr Gly Pro Lys Ala Tyr Leu Ile 
1               5                   10                  15      


Tyr Ser Ser Ser Val Ala Ala Gly Ala Gln Ser Gly Ile Glu Glu Cys 
            20                  25                  30          


Lys Tyr Gln Phe Ala Trp Asp Arg Trp Asn Cys Pro Glu Arg Ala Leu 
        35                  40                  45              


Gln Leu Ser Ser His Gly Gly Leu Arg Ser Ala Asn Arg Glu Thr Ala 
    50                  55                  60                  


Phe Val His Ala Ile Ser Ser Ala Gly Val Met Tyr Thr Leu Thr Arg 
65                  70                  75                  80  


Asn Cys Ser Leu Gly Asp Phe Asp Asn Cys Gly Cys Asp Asp Ser Arg 
                85                  90                  95      


Asn Gly Gln Leu Gly Gly Gln Gly Trp Leu Trp Gly Gly Cys Ser Asp 
            100                 105                 110         


Asn Val Gly Phe Gly Glu Ala Ile Ser Lys Gln Phe Val Asp Ala Leu 
        115                 120                 125             


Glu Thr Gly Gln Asp Ala Arg Ala Ala Met Asn Leu His Asn Asn Glu 
    130                 135                 140                 


Ala Gly Arg Lys Ala Val Lys Gly Thr Met Lys Arg Thr Cys Lys Cys 
145                 150                 155                 160 


His Gly Val Ser Gly Ser Cys Thr Thr Gln Thr Cys Trp Leu Gln Leu 
                165                 170                 175     


Pro Glu Phe Arg Glu Val Gly Ala His Leu Lys Glu Lys Tyr His Ala 
            180                 185                 190         


Ala Leu Lys Val Asp Leu Leu Gln Gly Ala Gly Asn Ser Ala Ala Gly 
        195                 200                 205             


Arg Gly Ala Ile Ala Asp Thr Phe Arg Ser Ile Ser Thr Arg Glu Leu 
    210                 215                 220                 


Val His Leu Glu Asp Ser Pro Asp Tyr Cys Leu Glu Asn Lys Thr Leu 
225                 230                 235                 240 


Gly Leu Leu Gly Thr Glu Gly Arg Glu Cys Leu Arg Arg Gly Arg Ala 
                245                 250                 255     


Leu Gly Arg Trp Glu Arg Arg Ser Cys Arg Arg Leu Cys Gly Asp Cys 
            260                 265                 270         


Gly Leu Ala Val Glu Glu Arg Arg Ala Glu Thr Val Ser Ser Cys Asn 
        275                 280                 285             


Cys Lys Phe His Trp Cys Cys Ala Val Arg Cys Glu Gln Cys Arg Arg 
    290                 295                 300                 


Arg Val Thr Lys Tyr Phe Cys Ser Arg Ala Glu Arg Pro Arg Gly Gly 
305                 310                 315                 320 


Ala Ala His Lys Pro Gly Arg Lys Pro 
                325                 


<210>  2761
<211>  115
<212>  PRT
<213>  Homo Sapiens

<400>  2761

Lys Phe Asp Asp Phe Glu Asp Glu Glu Asp Ile Val Glu Tyr Asp Asp 
1               5                   10                  15      


Asn Asp Phe Ala Glu Phe Glu Asp Val Met Glu Asp Ser Val Thr Glu 
            20                  25                  30          


Ser Pro Gln Arg Val Ile Ile Thr Glu Asp Asp Glu Asp Glu Thr Thr 
        35                  40                  45              


Val Glu Leu Glu Gly Gln Asp Glu Asn Gln Glu Gly Asp Phe Glu Asp 
    50                  55                  60                  


Ala Asp Thr Gln Glu Gly Asp Thr Glu Ser Glu Pro Tyr Asp Asp Glu 
65                  70                  75                  80  


Glu Phe Glu Gly Tyr Glu Asp Lys Pro Asp Thr Ser Ser Ser Lys Asn 
                85                  90                  95      


Lys Asp Pro Ile Thr Ile Val Asp Val Pro Ala His Leu Gln Asn Ser 
            100                 105                 110         


Trp Glu Ser 
        115 


<210>  2762
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  2762

Trp Ser Ile Gly Ala Ala Pro Phe Ser Gly Arg Arg Asn Trp Cys Ser 
1               5                   10                  15      


Tyr Val Val Thr Arg Thr Ile Ser Cys His Val Gln Asn Gly Thr Tyr 
            20                  25                  30          


Leu Gln Arg Val Leu Gln Asn Cys Pro Trp Pro Met Ser Cys Pro Gly 
        35                  40                  45              


Ser Ser Tyr Arg Thr Val Val Arg Pro Thr Tyr Lys Val Met Tyr Lys 
    50                  55                  60                  


Ile Val Thr Ala Arg Glu Trp Arg Cys Cys Pro Gly His Ser Gly Val 
65                  70                  75                  80  


Ser Cys Glu Glu Val Ala Ala Ser Ser Ala Ser Leu Glu Pro Met Trp 
                85                  90                  95      


Ser Gly Ser Thr Met Arg Arg Met Ala Leu Arg Pro Thr Ala Phe Ser 
            100                 105                 110         


Gly Cys Leu Asn Cys Ser Lys Val Ser Glu Leu Thr Glu Arg Leu Lys 
        115                 120                 125             


Val Leu Glu Ala Lys Met Thr Met Leu Thr Val Ile Glu Gln Pro Val 
    130                 135                 140                 


Pro Pro Thr Pro Ala Thr Pro Glu Asp Pro Ala Pro Leu Trp Gly Pro 
145                 150                 155                 160 


Pro Pro Ala Gln Gly Ser Pro Gly Asp Gly Gly Leu Gln Asp Gln Val 
                165                 170                 175     


Gly Ala Trp Gly Leu Pro Gly Pro Thr Gly Pro Lys Gly Asp Ala Gly 
            180                 185                 190         


Ser Arg Gly Pro Met Gly Met Arg Gly Pro Pro Gly Pro Gln Gly Pro 
        195                 200                 205             


Pro Gly Ser Pro Gly Arg Ala Gly Ala Val Gly Thr Pro Gly Glu Arg 
    210                 215                 220                 


Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Gly Pro Pro Ala 
225                 230                 235                 240 


Pro Val Gly Pro Pro His Ala Arg Ile Ser Gln His Gly Asp Pro Leu 
                245                 250                 255     


Leu Ser Asn Thr Phe Thr Glu Thr Asn Asn His Trp Pro Gln Gly Pro 
            260                 265                 270         


Thr Gly Pro Pro Gly Pro Pro Gly Pro Met Gly Pro Pro Gly Pro Pro 
        275                 280                 285             


Gly Pro Thr Gly Val Pro Gly Ser Pro Gly His Ile Gly Pro Pro Gly 
    290                 295                 300                 


Pro Thr Gly Pro Lys Gly Ile Ser Gly His Pro Gly Glu Lys Gly Glu 
305                 310                 315                 320 


Arg Gly Leu Arg Gly Glu Pro Gly Pro Gln Gly Ser Ala Gly Gln Arg 
                325                 330                 335     


Gly Glu Pro Gly Pro Lys Gly Asp Pro Gly Glu Lys Ser His Trp Gly 
            340                 345                 350         


Glu Gly Leu His Gln Leu Arg Glu Ala Leu Lys Ile Leu Ala Glu Arg 
        355                 360                 365             


Val Leu Ile Leu Glu Thr Met Ile Gly Leu Tyr Glu Pro Glu Leu Gly 
    370                 375                 380                 


Ser Gly Ala Gly Pro Ala Gly Thr Gly Thr Pro Ser Leu Leu Arg Gly 
385                 390                 395                 400 


Lys Arg Gly Gly His Ala Thr Asn Tyr Arg Ile Val Ala Pro Arg Ser 
                405                 410                 415     


Arg Asp Glu Arg Gly 
            420     


<210>  2763
<211>  556
<212>  PRT
<213>  Homo Sapiens

<400>  2763

Val Gly Arg Gly Leu Gly Arg Ala Ser Pro Ala Gly Gly Pro Leu Glu 
1               5                   10                  15      


Asp Val Val Ile Glu Arg Tyr His Ile Pro Arg Ala Cys Pro Arg Glu 
            20                  25                  30          


Val Gln Met Gly Asp Phe Val Arg Tyr His Tyr Asn Gly Thr Phe Glu 
        35                  40                  45              


Asp Gly Lys Lys Phe Asp Ser Ser Tyr Asp Arg Asn Thr Leu Val Ala 
    50                  55                  60                  


Ile Val Val Gly Val Gly Arg Leu Ile Thr Gly Met Asp Arg Gly Leu 
65                  70                  75                  80  


Met Gly Met Cys Val Asn Glu Arg Arg Arg Leu Ile Val Pro Pro His 
                85                  90                  95      


Leu Gly Tyr Gly Ser Ile Gly Leu Ala Gly Leu Ile Pro Pro Asp Ala 
            100                 105                 110         


Thr Leu Tyr Phe Asp Val Val Leu Leu Asp Val Trp Asn Lys Glu Asp 
        115                 120                 125             


Thr Val Gln Val Ser Thr Leu Leu Arg Pro Pro His Cys Pro Arg Met 
    130                 135                 140                 


Val Gln Asp Gly Asp Phe Val Arg Tyr His Tyr Asn Gly Thr Leu Leu 
145                 150                 155                 160 


Asp Gly Thr Ser Phe Asp Thr Ser Tyr Ser Lys Gly Gly Thr Tyr Asp 
                165                 170                 175     


Thr Tyr Val Gly Ser Gly Trp Leu Ile Lys Gly Met Asp Gln Gly Leu 
            180                 185                 190         


Leu Gly Met Cys Pro Gly Glu Arg Arg Lys Ile Ile Ile Pro Pro Phe 
        195                 200                 205             


Leu Ala Tyr Gly Glu Lys Gly Tyr Gly Thr Val Ile Pro Pro Gln Ala 
    210                 215                 220                 


Ser Leu Val Phe His Val Leu Leu Ile Asp Val His Asn Pro Lys Asp 
225                 230                 235                 240 


Ala Val Gln Leu Glu Thr Leu Glu Leu Pro Pro Gly Cys Val Arg Arg 
                245                 250                 255     


Ala Gly Ala Gly Asp Phe Met Arg Tyr His Tyr Asn Gly Ser Leu Met 
            260                 265                 270         


Asp Gly Thr Leu Phe Asp Ser Ser Tyr Ser Arg Asn His Thr Tyr Asn 
        275                 280                 285             


Thr Tyr Ile Gly Gln Gly Tyr Ile Ile Pro Gly Met Asp Gln Gly Leu 
    290                 295                 300                 


Gln Gly Ala Cys Met Gly Glu Arg Arg Arg Ile Thr Ile Pro Pro His 
305                 310                 315                 320 


Leu Ala Tyr Gly Glu Asn Gly Thr Gly Asp Lys Ile Pro Gly Ser Ala 
                325                 330                 335     


Val Leu Ile Phe Asn Val His Val Ile Asp Phe His Asn Pro Ala Asp 
            340                 345                 350         


Val Val Glu Ile Arg Thr Leu Ser Arg Pro Ser Glu Thr Cys Asn Glu 
        355                 360                 365             


Thr Thr Lys Leu Gly Asp Phe Val Arg Tyr His Tyr Asn Cys Ser Leu 
    370                 375                 380                 


Leu Asp Gly Thr Gln Leu Phe Thr Ser His Asp Tyr Gly Ala Pro Gln 
385                 390                 395                 400 


Glu Ala Thr Leu Gly Ala Asn Lys Val Ile Glu Gly Leu Asp Thr Gly 
                405                 410                 415     


Leu Gln Gly Met Cys Val Gly Glu Arg Arg Gln Leu Ile Val Pro Pro 
            420                 425                 430         


His Leu Ala His Gly Glu Ser Gly Ala Arg Gly Val Pro Gly Ser Ala 
        435                 440                 445             


Val Leu Leu Phe Glu Val Glu Leu Val Ser Arg Glu Asp Gly Leu Pro 
    450                 455                 460                 


Thr Gly Tyr Leu Phe Val Trp His Lys Asp Pro Pro Ala Asn Leu Phe 
465                 470                 475                 480 


Glu Asp Met Asp Leu Asn Lys Asp Gly Glu Val Pro Pro Glu Glu Phe 
                485                 490                 495     


Ser Thr Phe Ile Lys Ala Gln Val Ser Glu Gly Lys Gly Arg Leu Met 
            500                 505                 510         


Pro Gly Gln Asp Pro Glu Lys Thr Ile Gly Asp Met Phe Gln Asn Gln 
        515                 520                 525             


Asp Arg Asn Gln Asp Gly Lys Ile Thr Val Asp Glu Leu Lys Leu Lys 
    530                 535                 540                 


Ser Asp Glu Asp Glu Glu Arg Val His Glu Glu Leu 
545                 550                 555     


<210>  2764
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2764

Thr Leu Ala Pro Gly Trp Arg Leu Val Lys Gly Phe Leu Asn Gln Pro 
1               5                   10                  15      


Val Asp Val Glu Leu Tyr Gln Gly Leu Trp Asp Met Cys Arg Glu Gln 
            20                  25                  30          


Ser Ser Arg Glu Arg Glu Cys Gly Gln Thr Asp Gln Trp Gly Tyr Phe 
        35                  40                  45              


Glu Ala Gln Pro Val Leu Val Ala Arg 
    50                  55          


<210>  2765
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  2765

Pro His Leu Arg Thr Phe Thr Asp Arg Phe Gln Thr Cys Lys Val Gln 
1               5                   10                  15      


Gly Ala Trp Pro Leu Ile Asp Asn Asn Tyr Leu Asn Val Gln Val Thr 
            20                  25                  30          


Asn Thr Pro Val Leu Pro Gly Ser Ala Ala Thr Ala Thr Ser Lys Leu 
        35                  40                  45              


Thr Ile Ile Phe Lys Asn Phe Gln Glu Cys Val Asp Gln Lys Val Tyr 
    50                  55                  60                  


Gln Ala Glu Met Asp Glu Leu Pro Ala Ala Phe Val Asp Gly Ser Lys 
65                  70                  75                  80  


Asn Gly Gly Asp Lys His Gly Ala Asn Ser Leu Lys Ile Thr Glu Lys 
                85                  90                  95      


Val Ser Gly Gln His Val Glu Ile Gln Ala Lys Tyr Ile Gly Thr Thr 
            100                 105                 110         


Ile Val Val Arg Gln Val Gly Arg Tyr Leu Thr Phe Ala Val Arg Met 
        115                 120                 125             


Pro Glu Glu Val Val Asn Ala Val Glu Asp Trp Asp Ser Gln Gly Leu 
    130                 135                 140                 


Tyr Leu Cys Leu Arg Gly Cys Pro Leu Asn Gln Gln Ile Asp Phe Gln 
145                 150                 155                 160 


Ala Phe His Thr Asn Ala Glu Gly Thr Gly Ala Arg Arg Leu Ala Ala 
                165                 170                 175     


Ala Ser Pro Ala Pro Thr Ala Pro Glu Thr Phe Pro Tyr Glu Thr Ala 
            180                 185                 190         


Val Ala Lys Cys Lys Glu Lys Leu Pro Val Glu Asp Leu Tyr Tyr Gln 
        195                 200                 205             


Ala Cys Val Phe Asp Leu Leu Thr Thr Gly Asp Val Asn Phe Thr Leu 
    210                 215                 220                 


Ala Ala Tyr Tyr Ala Leu Glu Asp Val Lys Met Leu His Ser Asn Lys 
225                 230                 235                 240 


Asp Lys Leu His Leu Tyr Glu Arg Thr Arg Asp Leu Pro Gly Arg Ala 
                245                 250                 255     


<210>  2766
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  2766

Phe Ser Leu His Cys Pro Ser Val Pro Met Ala Gly Val Thr Ala Ser 
1               5                   10                  15      


Tyr Gly Gly Ser Leu Leu Pro Glu Gly His Leu Asn Leu Thr Ala Pro 
            20                  25                  30          


Cys Asn Ala Ala Cys Ser Cys Gln Pro Glu His Tyr Ser Pro Val Cys 
        35                  40                  45              


Gly Ser Asp Gly Leu Met Tyr Phe Ser Leu Cys His Ala Gly Cys Pro 
    50                  55                  60                  


Ala Ala Thr Glu Thr Asn Val Asp Gly Gln Lys Val Tyr Arg Asp Cys 
65                  70                  75                  80  


Ser Cys Ile Pro Gln Asn Leu Ser Ser Gly Phe Gly His Ala Thr Ala 
                85                  90                  95      


Gly Lys Cys Thr Ser Thr Cys Gln Arg Lys Pro Leu Leu 
            100                 105                 


<210>  2767
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  2767

Tyr Met Ser Phe Ser Met Lys Thr Ile Arg Leu Pro Arg Trp Leu Ala 
1               5                   10                  15      


Ala Ser Pro Thr Lys Glu Ile Gln Val Lys Lys Tyr Lys Cys Gly Leu 
            20                  25                  30          


Ile Lys Pro Cys Pro Ala Asn Tyr Phe Ala Phe Lys Ile Cys Ser Gly 
        35                  40                  45              


Ala Ala Asn Val Val Gly Pro Thr Met Cys Phe Glu Asp Arg Met Ile 
    50                  55                  60                  


Met Ser Pro Val Lys Asn Asn Val Gly Arg Gly Leu Asn Ile Ala Leu 
65                  70                  75                  80  


Val Asn Gly Thr Thr Gly Ala Val Leu Gly Gln Lys Ala Phe Asp Met 
                85                  90                  95      


Tyr Ser Gly Asp Val Met His Leu Val Lys Phe Leu Lys Glu Ile Pro 
            100                 105                 110         


Gly Gly Ala Leu Val Leu Val Ala Ser Tyr Asp Asp Pro Gly Thr Lys 
        115                 120                 125             


Met Asn Asp Glu Ser Arg Lys Leu Phe Ser Asp Leu Gly Ser Ser Tyr 
    130                 135                 140                 


Ala Lys Gln Leu Gly Phe Arg Asp Ser Trp Val Phe Ile Gly Ala Lys 
145                 150                 155                 160 


Asp Leu Arg Gly Lys Ser Pro Phe Glu Gln Phe Leu Lys Asn Ser Pro 
                165                 170                 175     


Asp Thr Asn Lys Tyr Glu Gly Trp Pro Glu Leu Leu Glu Met Glu Gly 
            180                 185                 190         


Cys Met Pro Pro Lys Pro Phe 
        195                 


<210>  2768
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  2768

Ser Glu Ile Pro Lys Gly Lys Gln Lys Ala Gln Leu Arg Gln Arg Glu 
1               5                   10                  15      


Val Val Asp Leu Tyr Asn Gly Met Cys Leu Gln Gly Pro Ala Gly Val 
            20                  25                  30          


Pro Gly Arg Asp Gly Ser Pro Gly Ala Asn Gly Ile Pro Gly Thr Pro 
        35                  40                  45              


Gly Ile Pro Gly Arg Asp Gly Phe Lys Gly Glu Lys Gly Glu Cys Leu 
    50                  55                  60                  


Arg Glu Ser Phe Glu Glu Ser Trp Thr Pro Asn Tyr Lys Gln Cys Ser 
65                  70                  75                  80  


Trp Ser Ser Leu Asn Tyr Gly Ile Asp Leu Gly Lys Ile Ala Glu Cys 
                85                  90                  95      


Thr Phe Thr Lys Met Arg Ser Asn Ser Ala Leu Arg Val Leu Phe Ser 
            100                 105                 110         


Gly Ser Leu Arg Leu Lys Cys Arg Asn Ala Cys Cys Gln Arg Trp Tyr 
        115                 120                 125             


Phe Thr Phe Asn Gly Ala Glu Cys Ser Gly Pro Leu Pro Ile Glu Ala 
    130                 135                 140                 


Ile Ile Tyr Leu Asp Gln Gly Ser Pro Glu Met Asn Ser Thr Ile Asn 
145                 150                 155                 160 


Ile His Arg Thr Ser Ser Val Glu Gly Leu Cys Glu Gly Ile Gly Ala 
                165                 170                 175     


Gly Leu Val Asp Val Ala Ile Trp Val Gly Thr Cys Ser Asp Tyr Pro 
            180                 185                 190         


Lys Gly Asp Ala Ser Thr Gly Trp Asn Ser Val Ser Arg Ile Ile Ile 
        195                 200                 205             


Glu Glu Leu Pro Lys 
    210             


<210>  2769
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  2769

Lys Pro Ser Pro Asp Ala Gly Pro His Gly Gln Gly Arg Val His Gln 
1               5                   10                  15      


Ala Ala Pro Leu Ser Asp Ala Pro His Asp Asp Ala His Gly Asn Phe 
            20                  25                  30          


Gln Tyr Asp His Glu Ala Phe Leu Gly Arg Glu Val Ala Lys Glu Phe 
        35                  40                  45              


Asp Gln Leu Thr Pro Glu Glu Ser Gln Ala Arg Leu Gly Arg Ile Val 
    50                  55                  60                  


Asp Arg Met Asp Arg Ala Gly Asp Gly Asp Gly Trp Val Ser Leu Ala 
65                  70                  75                  80  


Glu Leu Arg Ala Trp Ile Ala His Thr Gln Gln Arg His Ile Arg Asp 
                85                  90                  95      


Ser Val Ser Ala Ala Trp Asp Thr Tyr Asp Thr Asp Arg Asp Gly Arg 
            100                 105                 110         


Val Gly Trp Glu Glu Leu Arg Asn Ala Thr Tyr Gly His Tyr Ala Pro 
        115                 120                 125             


Gly Glu Glu Phe His Asp Val Glu Asp Ala Glu Thr Tyr Lys Lys Met 
    130                 135                 140                 


Leu Ala Arg Asp Glu Arg Arg Phe Arg Val Ala Asp Gln Asp Gly Asp 
145                 150                 155                 160 


Ser Met Ala Thr Arg Glu Glu Leu Thr Ala Phe Leu His Pro Glu Glu 
                165                 170                 175     


Phe Pro His Met Arg Asp Ile Val Ile Ala Glu Thr Leu Glu Asp Leu 
            180                 185                 190         


Asp Arg Asn Lys Asp Gly Tyr Val Gln Val Glu Glu Tyr Ile Ala Asp 
        195                 200                 205             


Leu Tyr Ser Ala Glu Pro Gly Glu Glu Glu Pro Ala Trp Val Gln Thr 
    210                 215                 220                 


Glu Arg Gln Gln Phe Arg Asp Phe Arg Asp Leu Asn Lys Asp Gly His 
225                 230                 235                 240 


Leu Asp Gly Ser Glu Val Gly His Trp Val Leu Pro Pro Ala Gln Asp 
                245                 250                 255     


Gln Pro Leu Val Glu Ala Asn His Leu Leu His Glu Ser Asp Thr Asp 
            260                 265                 270         


Lys Asp Gly Arg Leu Ser Lys Ala Glu Ile Leu Gly Asn Trp Asn Met 
        275                 280                 285             


Phe Val Gly Ser Gln Ala Thr Asn Tyr Gly Glu Asp Leu Thr Arg His 
    290                 295                 300                 


His Asp Glu Leu 
305             


<210>  2770
<211>  156
<212>  PRT
<213>  Homo Sapiens

<400>  2770

Gly Lys Met Tyr Gly Pro Gly Gly Gly Lys Tyr Phe Ser Thr Thr Glu 
1               5                   10                  15      


Asp Tyr Asp His Glu Ile Thr Gly Leu Arg Val Ser Val Gly Leu Leu 
            20                  25                  30          


Leu Val Lys Ser Val Gln Val Lys Leu Gly Asp Ser Trp Asp Val Lys 
        35                  40                  45              


Leu Gly Ala Leu Gly Gly Asn Thr Gln Glu Val Thr Leu Gln Pro Gly 
    50                  55                  60                  


Glu Tyr Ile Thr Lys Val Phe Val Ala Phe Gln Ala Phe Leu Arg Gly 
65                  70                  75                  80  


Met Val Met Tyr Thr Ser Lys Asp Arg Tyr Phe Tyr Phe Gly Lys Leu 
                85                  90                  95      


Asp Gly Gln Ile Ser Ser Ala Tyr Pro Ser Gln Glu Gly Gln Val Leu 
            100                 105                 110         


Val Gly Ile Tyr Gly Gln Tyr Gln Leu Leu Gly Ile Lys Ser Ile Gly 
        115                 120                 125             


Phe Glu Trp Asn Tyr Pro Leu Glu Glu Pro Thr Thr Glu Pro Pro Val 
    130                 135                 140                 


Asn Leu Thr Tyr Ser Ala Asn Ser Pro Val Gly Arg 
145                 150                 155     


<210>  2771
<211>  124
<212>  PRT
<213>  Homo Sapiens

<400>  2771

Gln Thr Leu Lys Asp Thr Thr Ser Ser Ser Ser Ala Asp Ser Thr Ile 
1               5                   10                  15      


Met Asp Ile Gln Val Pro Thr Arg Ala Pro Asp Ala Val Tyr Thr Glu 
            20                  25                  30          


Leu Gln Pro Thr Ser Pro Thr Pro Thr Trp Pro Ala Asp Glu Thr Pro 
        35                  40                  45              


Gln Pro Gln Thr Gln Thr Gln Gln Leu Glu Gly Thr Asp Gly Pro Leu 
    50                  55                  60                  


Val Thr Asp Pro Glu Thr His Lys Ser Thr Lys Ala Ala His Pro Thr 
65                  70                  75                  80  


Asp Asp Thr Thr Thr Leu Ser Glu Arg Pro Ser Pro Ser Thr Asp Val 
                85                  90                  95      


Gln Thr Asp Pro Gln Thr Leu Lys Pro Ser Gly Phe His Glu Asp Asp 
            100                 105                 110         


Pro Phe Phe Tyr Asp Glu His Thr Leu Arg Lys Arg 
        115                 120                 


<210>  2772
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  2772

Gly Glu Asp Cys Leu Trp Tyr Leu Asp Arg Asn Gly Ser Trp His Pro 
1               5                   10                  15      


Gly Phe Asn Cys Glu Phe Phe Thr Phe Cys Cys Gly Thr Cys Tyr His 
            20                  25                  30          


Arg Tyr Cys Cys Arg Asp Leu Thr Leu Leu Ile Thr Glu Arg Gln Gln 
        35                  40                  45              


Lys His Cys Leu Ala Phe Ser Pro Lys Thr Ile Ala 
    50                  55                  60  


<210>  2773
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2773

Glu Val Glu Lys Ser Ser Asp Gly Pro Gly Ala Ala Gln Glu Pro Thr 
1               5                   10                  15      


Trp Leu Thr Asp Val Pro Ala Ala Met Glu Phe Ile Ala Ala Thr Glu 
            20                  25                  30          


Val Ala Val Ile Gly Phe Phe Gln Asp Leu Glu Ile Pro Ala Val Pro 
        35                  40                  45              


Ile Leu His Ser Met Val Gln Lys Phe Pro Gly Val Ser Phe Gly Ile 
    50                  55                  60                  


Ser Thr Asp Ser Glu Val Leu Thr His Tyr Asn Ile Thr Gly Asn Thr 
65                  70                  75                  80  


Ile Cys Leu Phe Arg Leu Val Asp Asn Glu Gln Leu Asn Leu Glu Asp 
                85                  90                  95      


Glu Asp Ile Glu Ser Ile Asp Ala Thr Lys Leu Ser Arg Phe Ile Glu 
            100                 105                 110         


Ile Asn Ser Leu His Met Val Thr Glu Tyr Asn Pro Val Thr Val Ile 
        115                 120                 125             


Gly Leu Phe Asn Ser Val Ile Gln Ile His Leu Leu Leu Ile Met Asn 
    130                 135                 140                 


Lys Ala Ser Pro Glu Tyr Glu Glu Asn Met His Arg Tyr Gln Lys Ala 
145                 150                 155                 160 


Ala Lys Leu Phe Gln Gly Lys Ile Leu Phe Ile Leu Val Asp Ser Gly 
                165                 170                 175     


Met Lys Glu Asn Gly Lys Val Ile Ser Phe Phe Lys Leu Lys Glu Ser 
            180                 185                 190         


Gln Leu Pro Ala Leu Ala Ile Tyr Gln Thr Leu Asp Asp Glu Trp Asp 
        195                 200                 205             


Thr Leu Pro Thr Ala Glu Val Ser Val Glu His Val Gln Asn Phe Cys 
    210                 215                 220                 


Asp Gly Phe Leu Ser Gly Lys Leu Leu Lys Glu Asn Arg Glu Ser Glu 
225                 230                 235                 240 


Gly Lys Thr Pro Lys Val Glu Leu 
                245             


<210>  2774
<211>  231
<212>  PRT
<213>  Homo Sapiens

<400>  2774

Glu Ser Leu Leu Asp Asn Leu Gly Asn Asp Leu Ser Asn Val Val Asp 
1               5                   10                  15      


Lys Leu Glu Pro Val Leu His Glu Gly Leu Glu Thr Val Asp Asn Thr 
            20                  25                  30          


Leu Lys Gly Ile Leu Glu Lys Leu Lys Val Asp Leu Gly Val Leu Gln 
        35                  40                  45              


Lys Ser Ser Ala Trp Gln Leu Ala Lys Gln Lys Ala Gln Glu Ala Glu 
    50                  55                  60                  


Lys Leu Leu Asn Asn Val Ile Ser Lys Leu Leu Pro Thr Asn Thr Asp 
65                  70                  75                  80  


Ile Phe Gly Leu Lys Ile Ser Asn Ser Leu Ile Leu Asp Val Lys Ala 
                85                  90                  95      


Glu Pro Ile Asp Asp Gly Lys Gly Leu Asn Leu Ser Phe Pro Val Thr 
            100                 105                 110         


Ala Asn Val Thr Val Ala Gly Pro Ile Ile Gly Gln Ile Ile Asn Leu 
        115                 120                 125             


Lys Ala Ser Leu Asp Leu Leu Thr Ala Val Thr Ile Glu Thr Asp Pro 
    130                 135                 140                 


Gln Thr His Gln Pro Val Ala Val Leu Gly Glu Cys Ala Ser Asp Pro 
145                 150                 155                 160 


Thr Ser Ile Ser Leu Ser Leu Leu Asp Lys His Ser Gln Ile Ile Asn 
                165                 170                 175     


Lys Phe Val Asn Ser Val Ile Asn Thr Leu Lys Ser Thr Val Ser Ser 
            180                 185                 190         


Leu Leu Gln Lys Glu Ile Cys Pro Leu Ile Arg Ile Phe Ile His Ser 
        195                 200                 205             


Leu Asp Val Asn Val Ile Gln Gln Val Val Asp Asn Pro Gln His Lys 
    210                 215                 220                 


Thr Gln Leu Gln Thr Leu Ile 
225                 230     


<210>  2775
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  2775

Asn Pro Thr Thr Ala Ala Pro Ala Asp Thr Tyr Pro Ala Thr Gly Pro 
1               5                   10                  15      


Ala Asp Asp Glu Ala Pro Asp Ala Glu Thr Thr Ala Ala Ala Thr Thr 
            20                  25                  30          


Ala Thr Thr Ala Ala Pro Thr Thr Ala Thr Thr Ala Ala Ser Thr Thr 
        35                  40                  45              


Ala Arg Lys Asp Ile Pro Val Leu Pro Lys Trp Val Gly Asp Leu Pro 
    50                  55                  60                  


Asn Gly Arg Val Cys Pro 
65                  70  


<210>  2776
<211>  560
<212>  PRT
<213>  Homo Sapiens

<400>  2776

Gln Gly Leu Leu Leu Thr Leu Glu Glu His Ile Ala His Phe Leu Gly 
1               5                   10                  15      


Thr Gly Gly Ala Ala Thr Thr Met Gly Asn Ser Cys Ile Cys Arg Asp 
            20                  25                  30          


Asp Ser Gly Thr Asp Asp Ser Val Asp Thr Gln Gln Gln Gln Ala Glu 
        35                  40                  45              


Asn Ser Ala Val Pro Thr Ala Asp Thr Arg Ser Gln Pro Arg Asp Pro 
    50                  55                  60                  


Val Arg Pro Pro Arg Arg Gly Arg Gly Pro His Glu Pro Arg Arg Lys 
65                  70                  75                  80  


Lys Gln Asn Val Asp Gly Leu Val Leu Asp Thr Leu Ala Val Ile Arg 
                85                  90                  95      


Thr Leu Val Asp Asn Asp Gln Glu Pro Pro Tyr Ser Met Ile Thr Leu 
            100                 105                 110         


His Glu Met Ala Glu Thr Asp Glu Gly Trp Leu Asp Val Val Gln Ser 
        115                 120                 125             


Leu Ile Arg Val Ile Pro Leu Glu Asp Pro Leu Gly Pro Ala Val Ile 
    130                 135                 140                 


Thr Leu Leu Leu Asp Glu Cys Pro Leu Pro Thr Lys Asp Ala Leu Gln 
145                 150                 155                 160 


Lys Leu Thr Glu Ile Leu Asn Leu Asn Gly Glu Val Ala Cys Gln Asp 
                165                 170                 175     


Ser Ser His Pro Ala Lys His Arg Asn Thr Ser Ala Val Leu Gly Cys 
            180                 185                 190         


Leu Ala Glu Lys Leu Ala Gly Pro Ala Ser Ile Gly Leu Leu Ser Pro 
        195                 200                 205             


Gly Ile Leu Glu Tyr Leu Leu Gln Cys Leu Lys Leu Gln Ser His Pro 
    210                 215                 220                 


Thr Val Met Leu Phe Ala Leu Ile Ala Leu Glu Lys Phe Ala Gln Thr 
225                 230                 235                 240 


Ser Glu Asn Lys Leu Thr Ile Ser Glu Ser Ser Ile Ser Asp Arg Leu 
                245                 250                 255     


Val Thr Leu Glu Ser Trp Ala Asn Asp Pro Asp Tyr Leu Lys Arg Gln 
            260                 265                 270         


Val Gly Phe Cys Ala Gln Trp Ser Leu Asp Asn Leu Phe Leu Lys Glu 
        275                 280                 285             


Gly Arg Gln Leu Thr Tyr Glu Lys Val Asn Leu Ser Ser Ile Arg Ala 
    290                 295                 300                 


Met Leu Asn Ser Asn Asp Val Ser Glu Tyr Leu Lys Ile Ser Pro His 
305                 310                 315                 320 


Gly Leu Glu Ala Arg Cys Asp Ala Ser Ser Phe Glu Ser Val Arg Cys 
                325                 330                 335     


Thr Phe Cys Val Asp Ala Gly Val Trp Tyr Tyr Glu Val Thr Val Val 
            340                 345                 350         


Thr Ser Gly Val Met Gln Ile Gly Trp Ala Thr Arg Asp Ser Lys Phe 
        355                 360                 365             


Leu Asn His Glu Gly Tyr Gly Ile Gly Asp Asp Glu Tyr Ser Cys Ala 
    370                 375                 380                 


Tyr Asp Gly Cys Arg Gln Leu Ile Trp Tyr Asn Ala Arg Ser Lys Pro 
385                 390                 395                 400 


His Ile His Pro Cys Trp Lys Glu Gly Asp Thr Val Gly Phe Leu Leu 
                405                 410                 415     


Asp Leu Asn Glu Lys Gln Met Ile Phe Phe Leu Asn Gly Asn Gln Leu 
            420                 425                 430         


Pro Pro Glu Lys Gln Val Phe Ser Ser Thr Val Ser Gly Phe Phe Ala 
        435                 440                 445             


Ala Ala Ser Phe Met Ser Tyr Gln Gln Cys Glu Phe Asn Phe Gly Ala 
    450                 455                 460                 


Lys Pro Phe Lys Tyr Pro Pro Ser Met Lys Phe Ser Thr Phe Asn Asp 
465                 470                 475                 480 


Tyr Ala Phe Leu Thr Ala Glu Glu Lys Ile Ile Leu Pro Arg His Arg 
                485                 490                 495     


Arg Leu Ala Leu Leu Lys Gln Val Ser Ile Arg Glu Asn Cys Cys Ser 
            500                 505                 510         


Leu Cys Cys Asp Glu Val Ala Asp Thr Gln Leu Lys Pro Cys Gly His 
        515                 520                 525             


Ser Asp Leu Cys Met Asp Cys Ala Leu Gln Leu Glu Thr Cys Pro Leu 
    530                 535                 540                 


Cys Arg Lys Glu Ile Val Ser Arg Ile Arg Gln Ile Ser His Ile Ser 
545                 550                 555                 560 


<210>  2777
<211>  450
<212>  PRT
<213>  Homo Sapiens

<400>  2777

Leu Pro Gln Leu Ser Asp Asp Ile Pro Phe Arg Val Asn Trp Pro Gly 
1               5                   10                  15      


Thr Glu Phe Ser Leu Pro Thr Thr Gly Val Leu Tyr Lys Glu Asp Asn 
            20                  25                  30          


Tyr Val Ile Met Thr Thr Ala His Lys Glu Lys Tyr Lys Cys Ile Leu 
        35                  40                  45              


Pro Leu Val Thr Ser Gly Asp Glu Glu Glu Glu Lys Asp Tyr Lys Gly 
    50                  55                  60                  


Pro Asn Pro Arg Glu Leu Leu Glu Pro Leu Phe Lys Gln Ser Ser Cys 
65                  70                  75                  80  


Ser Tyr Arg Ile Glu Ser Tyr Trp Thr Tyr Glu Val Cys His Gly Lys 
                85                  90                  95      


His Ile Arg Gln Tyr His Glu Glu Lys Glu Thr Gly Gln Lys Ile Asn 
            100                 105                 110         


Ile His Glu Tyr Tyr Leu Gly Asn Met Leu Ala Lys Asn Leu Leu Phe 
        115                 120                 125             


Glu Lys Glu Arg Glu Ala Glu Glu Lys Glu Lys Ser Asn Glu Ile Pro 
    130                 135                 140                 


Thr Lys Asn Ile Glu Gly Gln Met Thr Pro Tyr Tyr Pro Val Gly Met 
145                 150                 155                 160 


Gly Asn Gly Thr Pro Cys Ser Leu Lys Gln Asn Arg Pro Arg Ser Ser 
                165                 170                 175     


Thr Val Met Tyr Ile Cys His Pro Glu Ser Lys His Glu Ile Leu Ser 
            180                 185                 190         


Val Ala Glu Val Thr Thr Cys Glu Tyr Glu Val Val Ile Leu Thr Pro 
        195                 200                 205             


Leu Leu Cys Ser His Pro Lys Tyr Arg Phe Arg Ala Ser Pro Val Asn 
    210                 215                 220                 


Asp Ile Phe Cys Gln Ser Leu Pro Gly Ser Pro Phe Lys Pro Leu Thr 
225                 230                 235                 240 


Leu Arg Gln Leu Glu Gln Gln Glu Glu Ile Leu Arg Val Pro Phe Arg 
                245                 250                 255     


Arg Asn Lys Glu Glu Asp Leu Gln Ser Thr Lys Glu Glu Arg Phe Pro 
            260                 265                 270         


Ala Ile His Lys Ser Ile Ala Ile Gly Ser Gln Pro Val Leu Thr Val 
        275                 280                 285             


Gly Thr Thr His Ile Ser Lys Leu Thr Asp Asp Gln Leu Ile Lys Glu 
    290                 295                 300                 


Phe Leu Ser Gly Ser Tyr Cys Phe Arg Gly Gly Val Gly Trp Trp Lys 
305                 310                 315                 320 


Tyr Glu Phe Cys Tyr Gly Lys His Val His Gln Tyr His Glu Asp Lys 
                325                 330                 335     


Asp Ser Gly Lys Thr Ser Val Val Val Gly Thr Trp Asn Gln Glu Glu 
            340                 345                 350         


His Ile Glu Trp Ala Lys Lys Asn Thr Ala Arg Ala Tyr His Leu Gln 
        355                 360                 365             


Asp Asp Gly Thr Gln Thr Val Arg Met Val Ser His Phe Tyr Gly Asn 
    370                 375                 380                 


Gly Asp Ile Cys Asp Ile Thr Asp Lys Pro Arg Gln Val Thr Val Lys 
385                 390                 395                 400 


Leu Lys Cys Lys Glu Ser Asp Ser Pro His Ala Val Thr Val Tyr Met 
                405                 410                 415     


Leu Glu Pro His Ser Cys Gln Tyr Ile Leu Gly Val Glu Ser Pro Val 
            420                 425                 430         


Ile Cys Lys Ile Leu Asp Thr Ala Asp Glu Asn Gly Leu Leu Ser Leu 
        435                 440                 445             


Pro Asn 
    450 


<210>  2778
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  2778

Leu Met Leu Leu His Tyr Thr Phe Gln Gln Pro Arg His Gln Ser Ser 
1               5                   10                  15      


Val Lys Leu Arg Glu Gln Ile Leu Asp Leu Ser Lys Arg Tyr Val Lys 
            20                  25                  30          


Ala Leu Ala Glu Glu Asn Lys Asn Thr Val Asp Val Glu Asn Gly Ala 
        35                  40                  45              


Ser Met Ala Gly Tyr Ala Asp Leu Lys Arg Thr Ile Ala Val Leu Leu 
    50                  55                  60                  


Asp Asp Ile Leu Gln Arg Leu Val Lys Leu Glu Asn Lys Val Asp Tyr 
65                  70                  75                  80  


Ile Val Val Asn Gly Ser Ala Ala Asn Thr Thr Asn Gly Thr Ser Gly 
                85                  90                  95      


Asn Leu Val Pro Val Thr Thr Asn Lys Arg Thr Asn Val Ser Gly Ser 
            100                 105                 110         


Ile Arg 
        


<210>  2779
<211>  509
<212>  PRT
<213>  Homo Sapiens

<400>  2779

Gly Phe Leu Tyr Pro Leu Val Asp Phe Cys Ile Ser Gly Lys Thr Arg 
1               5                   10                  15      


Gly Gln Lys Pro Asn Phe Val Ile Ile Leu Ala Asp Asp Met Gly Trp 
            20                  25                  30          


Gly Asp Leu Gly Ala Asn Trp Ala Glu Thr Lys Asp Thr Ala Asn Leu 
        35                  40                  45              


Asp Lys Met Ala Ser Glu Gly Met Arg Phe Val Asp Phe His Ala Ala 
    50                  55                  60                  


Ala Ser Thr Cys Ser Pro Ser Arg Ala Ser Leu Leu Thr Gly Arg Leu 
65                  70                  75                  80  


Gly Leu Arg Asn Gly Val Thr Arg Asn Phe Ala Val Thr Ser Val Gly 
                85                  90                  95      


Gly Leu Pro Leu Asn Glu Thr Thr Leu Ala Glu Val Leu Gln Gln Ala 
            100                 105                 110         


Gly Tyr Val Thr Gly Ile Ile Gly Lys Trp His Leu Gly His His Gly 
        115                 120                 125             


Ser Tyr His Pro Asn Phe Arg Gly Phe Asp Tyr Tyr Phe Gly Ile Pro 
    130                 135                 140                 


Tyr Ser His Asp Met Gly Cys Thr Asp Thr Pro Gly Tyr Asn His Pro 
145                 150                 155                 160 


Pro Cys Pro Ala Cys Pro Gln Gly Asp Gly Pro Ser Arg Asn Leu Gln 
                165                 170                 175     


Arg Asp Cys Tyr Thr Asp Val Ala Leu Pro Leu Tyr Glu Asn Leu Asn 
            180                 185                 190         


Ile Val Glu Gln Pro Val Asn Leu Ser Ser Leu Ala Gln Lys Tyr Ala 
        195                 200                 205             


Glu Lys Ala Thr Gln Phe Ile Gln Arg Ala Ser Thr Ser Gly Arg Pro 
    210                 215                 220                 


Phe Leu Leu Tyr Val Ala Leu Ala His Met His Val Pro Leu Pro Val 
225                 230                 235                 240 


Thr Gln Leu Pro Ala Ala Pro Arg Gly Arg Ser Leu Tyr Gly Ala Gly 
                245                 250                 255     


Leu Trp Glu Met Asp Ser Leu Val Gly Gln Ile Lys Asp Lys Val Asp 
            260                 265                 270         


His Thr Val Lys Glu Asn Thr Phe Leu Trp Phe Thr Gly Asp Asn Gly 
        275                 280                 285             


Pro Trp Ala Gln Lys Cys Glu Leu Ala Gly Ser Val Gly Pro Phe Thr 
    290                 295                 300                 


Gly Phe Trp Gln Thr Arg Gln Gly Gly Ser Pro Ala Lys Gln Thr Thr 
305                 310                 315                 320 


Trp Glu Gly Gly His Arg Val Pro Ala Leu Ala Tyr Trp Pro Gly Arg 
                325                 330                 335     


Val Pro Val Asn Val Thr Ser Thr Ala Leu Leu Ser Val Leu Asp Ile 
            340                 345                 350         


Phe Pro Thr Val Val Ala Leu Ala Gln Ala Ser Leu Pro Gln Gly Arg 
        355                 360                 365             


Arg Phe Asp Gly Val Asp Val Ser Glu Val Leu Phe Gly Arg Ser Gln 
    370                 375                 380                 


Pro Gly His Arg Val Leu Phe His Pro Asn Ser Gly Ala Ala Gly Glu 
385                 390                 395                 400 


Phe Gly Ala Leu Gln Thr Val Arg Leu Glu Arg Tyr Lys Ala Phe Tyr 
                405                 410                 415     


Ile Thr Gly Gly Ala Arg Ala Cys Asp Gly Ser Thr Gly Pro Glu Leu 
            420                 425                 430         


Gln His Lys Phe Pro Leu Ile Phe Asn Leu Glu Asp Asp Thr Ala Glu 
        435                 440                 445             


Ala Val Pro Leu Glu Arg Gly Gly Ala Glu Tyr Gln Ala Val Leu Pro 
    450                 455                 460                 


Glu Val Arg Lys Val Leu Ala Asp Val Leu Gln Asp Ile Ala Asn Asp 
465                 470                 475                 480 


Asn Ile Ser Ser Ala Asp Tyr Thr Gln Asp Pro Ser Val Thr Pro Cys 
                485                 490                 495     


Cys Asn Pro Tyr Gln Ile Ala Cys Arg Cys Gln Ala Ala 
            500                 505                 


<210>  2780
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2780

Met Asp Gly Asn Asp Asn Val Thr Leu Leu Phe Ala Pro Leu Leu Arg 
1               5                   10                  15      


Asp Asn Tyr Thr Leu Ala Pro Asn Ala Ser Ser Leu Gly Pro Gly Thr 
            20                  25                  30          


Asp Leu Ala Leu Ala Pro Ala Ser Ser Ala Gly Pro Gly Pro Gly Leu 
        35                  40                  45              


Ser Leu Gly Pro Gly Pro Ser Phe Gly Phe Ser Pro Gly Pro Thr Pro 
    50                  55                  60                  


Thr Pro Glu Pro Thr Thr Ser Gly Leu Ala Gly Gly Ala Ala Ser His 
65                  70                  75                  80  


Gly Pro Ser Pro Phe Pro Arg Pro Trp Ala Pro His Ala Leu Pro Phe 
                85                  90                  95      


Trp Asp Thr Pro Leu Asn His 
            100             


<210>  2781
<211>  429
<212>  PRT
<213>  Homo Sapiens

<400>  2781

Ala Ser Asn Asp Pro Arg Asn Phe Val Pro Asn Lys Met Trp Lys Gly 
1               5                   10                  15      


Leu Val Lys Arg Asn Ala Ser Val Glu Thr Val Asp Asn Lys Thr Ser 
            20                  25                  30          


Glu Asp Val Thr Met Ala Ala Ala Ser Pro Val Thr Leu Thr Lys Gly 
        35                  40                  45              


Thr Ser Ala Ala His Leu Asn Ser Met Glu Val Thr Thr Glu Asp Thr 
    50                  55                  60                  


Ser Arg Thr Asp Val Ser Glu Pro Ala Thr Ser Gly Val Ala Ala Asp 
65                  70                  75                  80  


Gly Val Thr Ser Ile Ala Pro Thr Ala Val Ala Ser Ser Thr Thr Ala 
                85                  90                  95      


Ala Ser Ile Thr Thr Ala Ala Ser Ser Met Thr Val Ala Ser Ser Ala 
            100                 105                 110         


Pro Thr Thr Ala Ala Ser Ser Thr Thr Val Ala Ser Ile Ala Pro Thr 
        115                 120                 125             


Thr Ala Ala Ser Ser Met Thr Ala Ala Ser Ser Thr Pro Met Thr Leu 
    130                 135                 140                 


Ala Leu Pro Ala Pro Thr Ser Thr Ser Thr Gly Arg Thr Pro Ser Thr 
145                 150                 155                 160 


Thr Ala Thr Gly His Pro Ser Leu Ser Thr Ala Leu Ala Gln Val Pro 
                165                 170                 175     


Lys Ser Ser Ala Leu Pro Arg Thr Ala Thr Leu Ala Thr Leu Ala Thr 
            180                 185                 190         


Arg Ala Gln Thr Val Ala Thr Thr Ala Asn Thr Ser Ser Pro Met Ser 
        195                 200                 205             


Thr Arg Pro Ser Pro Ser Lys His Met Pro Ser Asp Thr Ala Ala Ser 
    210                 215                 220                 


Pro Val Pro Pro Met Arg Pro Gln Ala Gln Gly Pro Ile Ser Gln Val 
225                 230                 235                 240 


Ser Val Asp Gln Pro Val Val Asn Thr Thr Asn Lys Ser Thr Pro Met 
                245                 250                 255     


Pro Ser Asn Thr Thr Pro Glu Pro Ala Pro Thr Pro Thr Val Val Thr 
            260                 265                 270         


Thr Thr Lys Ala Gln Ala Arg Glu Pro Thr Ala Ser Pro Val Pro Val 
        275                 280                 285             


Pro His Thr Ser Pro Ile Pro Glu Met Glu Ala Met Ser Pro Thr Thr 
    290                 295                 300                 


Gln Pro Ser Pro Met Pro Tyr Thr Gln Arg Ala Ala Gly Pro Gly Thr 
305                 310                 315                 320 


Ser Gln Ala Pro Glu Gln Val Glu Thr Glu Ala Thr Pro Gly Thr Asp 
                325                 330                 335     


Ser Thr Gly Pro Thr Pro Arg Ser Ser Gly Gly Thr Lys Met Pro Ala 
            340                 345                 350         


Thr Asp Ser Cys Gln Pro Ser Thr Gln Gly Gln Tyr Met Val Val Thr 
        355                 360                 365             


Thr Glu Pro Leu Thr Gln Ala Val Val Asp Lys Thr Leu Leu Leu Val 
    370                 375                 380                 


Val Leu Leu Leu Gly Val Thr Leu Phe Ile Thr Val Leu Val Leu Phe 
385                 390                 395                 400 


Ala Leu Gln Ala Tyr Glu Ser Tyr Lys Lys Lys Asp Tyr Thr Gln Val 
                405                 410                 415     


Asp Tyr Leu Ile Asn Gly Met Tyr Ala Asp Ser Glu Met 
            420                 425                 


<210>  2782
<211>  330
<212>  PRT
<213>  Homo Sapiens

<400>  2782

Arg Gly Tyr Leu Thr Arg Pro His Leu Val Ala Met Asp Pro Ala Ala 
1               5                   10                  15      


Pro Ala Pro Val Ala Gly Phe Pro Ala Val Thr Leu Cys Asn Ile Asn 
            20                  25                  30          


Arg Phe Arg His Ser Ala Leu Ser Asp Ala Asp Ile Phe His Leu Ala 
        35                  40                  45              


Asn Leu Thr Gly Leu Pro Pro Lys Asp Arg Asp Gly His Arg Ala Ala 
    50                  55                  60                  


Gly Leu Arg Tyr Pro Glu Pro Asp Met Val Asp Ile Leu Asn Arg Thr 
65                  70                  75                  80  


Gly His Gln Leu Ala Asp Met Leu Lys Ser Cys Asn Phe Ser Gly His 
                85                  90                  95      


His Cys Ser Ala Ser Asn Phe Ser Val Val Tyr Thr Arg Tyr Gly Lys 
            100                 105                 110         


Cys Tyr Thr Phe Asn Ala Asp Pro Arg Ser Ser Leu Pro Ser Arg Ala 
        115                 120                 125             


Gly Gly Met Gly Ser Gly Leu Glu Ile Met Leu Asp Ile Gln Gln Glu 
    130                 135                 140                 


Glu Tyr Leu Pro Ile Trp Arg Glu Thr Asn Glu Thr Ser Phe Glu Ala 
145                 150                 155                 160 


Gly Ile Arg Val Gln Ile His Ser Gln Glu Glu Pro Pro Tyr Ile His 
                165                 170                 175     


Gln Leu Gly Phe Gly Val Ser Pro Gly Phe Gln Thr Phe Val Ser Cys 
            180                 185                 190         


Gln Glu Gln Arg Leu Thr Tyr Leu Pro Gln Pro Trp Gly Asn Cys Arg 
        195                 200                 205             


Ala Glu Ser Glu Leu Arg Glu Pro Glu Leu Gln Gly Tyr Ser Ala Tyr 
    210                 215                 220                 


Ser Val Ser Ala Cys Arg Leu Arg Cys Glu Lys Glu Ala Val Leu Gln 
225                 230                 235                 240 


Arg Cys His Cys Arg Met Val His Met Pro Asp Ser Leu Gly Gly Gly 
                245                 250                 255     


Pro Glu Gly Pro Cys Phe Cys Pro Thr Pro Cys Asn Leu Thr Arg Tyr 
            260                 265                 270         


Gly Lys Glu Ile Ser Met Val Arg Ile Pro Asn Arg Gly Ser Ala Arg 
        275                 280                 285             


Tyr Leu Ala Arg Lys Tyr Asn Arg Asn Glu Thr Tyr Ile Arg Glu Asn 
    290                 295                 300                 


Phe Leu Val Leu Asp Val Phe Phe Glu Ala Leu Thr Ser Glu Ala Met 
305                 310                 315                 320 


Glu Gln Arg Ala Ala Tyr Gly Leu Ser Ala 
                325                 330 


<210>  2783
<211>  120
<212>  PRT
<213>  Homo Sapiens

<400>  2783

Leu His Thr Phe Leu Leu Tyr Leu Gly Pro His Ile Ala Ser Val Thr 
1               5                   10                  15      


Leu Ala Ala Tyr Glu Cys Asn Ser Val Asn Phe Pro Glu Pro Pro Tyr 
            20                  25                  30          


Pro Asp Gln Ile Ile Cys Pro Asp Glu Glu Gly Thr Glu Gly Thr Ile 
        35                  40                  45              


Phe Leu Trp Ser Ile Ile Ser Lys Val Arg Ile Glu Ala Cys Met Trp 
    50                  55                  60                  


Gly Ile Gly Thr Ala Ile Gly Glu Leu Pro Pro Tyr Phe Met Ala Arg 
65                  70                  75                  80  


Ala Ala Arg Leu Ser Gly Ala Glu Pro Asp Asp Glu Glu Tyr Gln Glu 
                85                  90                  95      


Phe Glu Glu Met Leu Glu His Ala Glu Ser Ala Gln Asp Phe Ala Ser 
            100                 105                 110         


Arg Ala Lys Leu Ala Val Gln Lys 
        115                 120 


<210>  2784
<211>  643
<212>  PRT
<213>  Homo Sapiens

<400>  2784

Asp Leu Ala Phe Ile Pro Pro Phe Ile Arg Met Ser Gly Pro Ala Val 
1               5                   10                  15      


Ser Ala Ser Leu Val Gly Asp Thr Glu Gly Val Thr Val Ser Leu Ala 
            20                  25                  30          


Val Leu Gln Asp Glu Ala Gly Ile Leu Pro Ile Pro Thr Cys Gly Val 
        35                  40                  45              


Leu Asn Asn Glu Thr Glu Asp Trp Ser Val Thr Val Ile Pro Gly Ala 
    50                  55                  60                  


Lys Val Leu Glu Val Thr Val Arg Trp Lys Arg Gly Leu Asp Trp Cys 
65                  70                  75                  80  


Ser Ser Asn Glu Thr Asp Ser Phe Ser Glu Ser Pro Cys Ile Leu Gln 
                85                  90                  95      


Thr Leu Leu Val Ser Ala Ser His Asn Ser Ser Cys Ser Ala His Leu 
            100                 105                 110         


Leu Ile Gln Val Glu Ile Tyr Ala Asn Ser Ser Leu Thr His Asn Ala 
        115                 120                 125             


Ser Glu Asn Val Thr Val Ile Pro Asn Gln Val Tyr Gln Pro Leu Gly 
    130                 135                 140                 


Pro Cys Pro Cys Asn Leu Thr Ala Gly Ala Cys Asp Val Arg Cys Cys 
145                 150                 155                 160 


Cys Asp Gln Glu Cys Ser Ser Asn Leu Thr Thr Leu Phe Arg Arg Ser 
                165                 170                 175     


Cys Phe Thr Gly Val Phe Gly Gly Asp Val Asn Pro Pro Phe Asp Gln 
            180                 185                 190         


Leu Cys Ser Ala Gly Thr Thr Thr Arg Gly Val Pro Asp Trp Phe Pro 
        195                 200                 205             


Phe Leu Cys Val Gln Ser Pro Leu Ala Asn Thr Pro Phe Leu Gly Tyr 
    210                 215                 220                 


Phe Tyr His Gly Ala Val Ser Pro Lys Gln Asp Ser Ser Phe Glu Val 
225                 230                 235                 240 


Tyr Val Asp Thr Asp Ala Lys Asp Phe Ala Asp Phe Gly Tyr Lys Gln 
                245                 250                 255     


Gly Asp Pro Ile Met Thr Val Lys Lys Ala Tyr Phe Thr Ile Pro Gln 
            260                 265                 270         


Val Ser Leu Ala Gly Gln Cys Met Gln Asn Ala Pro Val Ala Phe Leu 
        275                 280                 285             


His Asn Phe Asp Val Lys Cys Val Thr Asn Leu Glu Leu Tyr Gln Glu 
    290                 295                 300                 


Arg Asp Gly Ile Ile Asn Ala Lys Ile Lys Asn Val Ala Leu Gly Gly 
305                 310                 315                 320 


Ile Val Thr Pro Lys Val Ile Tyr Glu Glu Ala Thr Asp Leu Asp Lys 
                325                 330                 335     


Phe Ile Thr Asn Thr Glu Thr Pro Leu Asn Asn Gly Ser Thr Pro Arg 
            340                 345                 350         


Ile Val Asn Val Glu Glu His Tyr Ile Phe Lys Trp Asn Asn Asn Thr 
        355                 360                 365             


Ile Ser Glu Ile Asn Val Lys Ile Phe Arg Ala Glu Ile Asn Ala His 
    370                 375                 380                 


Gln Lys Gly Ile Met Thr Gln Arg Phe Val Val Lys Phe Leu Ser Tyr 
385                 390                 395                 400 


Asn Ser Gly Asn Glu Glu Glu Leu Ser Gly Asn Pro Gly Tyr Gln Leu 
                405                 410                 415     


Gly Lys Pro Val Arg Ala Leu Asn Ile Asn Arg Met Asn Asn Val Thr 
            420                 425                 430         


Thr Leu His Leu Trp Gln Ser Ala Gly Arg Gly Leu Cys Thr Ser Ala 
        435                 440                 445             


Thr Phe Lys Pro Ile Leu Phe Gly Glu Asn Val Leu Ser Gly Cys Leu 
    450                 455                 460                 


Leu Glu Val Gly Ile Asn Glu Asn Cys Thr Gln Leu Arg Glu Asn Ala 
465                 470                 475                 480 


Val Glu Arg Leu Asp Ser Leu Ile Gln Ala Thr His Val Ala Met Arg 
                485                 490                 495     


Gly Asn Ser Asp Tyr Ala Asp Leu Ser Asp Gly Trp Leu Glu Ile Ile 
            500                 505                 510         


Arg Val Asp Ala Pro Asp Pro Gly Ala Asp Pro Leu Ala Ser Ser Val 
        515                 520                 525             


Asn Gly Met Cys Leu Asp Ile Pro Ala His Leu Ser Ile Arg Ile Leu 
    530                 535                 540                 


Ile Ser Asp Ala Gly Ala Val Glu Gly Ile Thr Gln Gln Glu Ile Leu 
545                 550                 555                 560 


Gly Val Glu Thr Arg Phe Ser Ser Val Asn Trp Gln Tyr Gln Cys Gly 
                565                 570                 575     


Leu Thr Cys Glu His Lys Ala Asp Leu Leu Pro Ile Ser Ala Ser Val 
            580                 585                 590         


Gln Phe Ile Lys Ile Pro Ala Gln Leu Pro His Pro Leu Thr Arg Phe 
        595                 600                 605             


Gln Ile Asn Tyr Thr Glu Tyr Asp Cys Asn Arg Asn Glu Val Cys Trp 
    610                 615                 620                 


Pro Gln Leu Leu Tyr Pro Trp Thr Gln Tyr Tyr Gln Gly Glu Leu His 
625                 630                 635                 640 


Ser Gln Cys 
            


<210>  2785
<211>  445
<212>  PRT
<213>  Homo Sapiens

<400>  2785

Glu Glu Gln Pro Pro Glu Thr Ala Ala Gln Arg Cys Phe Cys Gln Val 
1               5                   10                  15      


Ser Gly Tyr Leu Asp Asp Cys Thr Cys Asp Val Glu Thr Ile Asp Arg 
            20                  25                  30          


Phe Asn Asn Tyr Arg Leu Phe Pro Arg Leu Gln Lys Leu Leu Glu Ser 
        35                  40                  45              


Asp Tyr Phe Arg Tyr Tyr Lys Val Asn Leu Lys Arg Pro Cys Pro Phe 
    50                  55                  60                  


Trp Asn Asp Ile Ser Gln Cys Gly Arg Arg Asp Cys Ala Val Lys Pro 
65                  70                  75                  80  


Cys Gln Ser Asp Glu Val Pro Asp Gly Ile Lys Ser Ala Ser Tyr Lys 
                85                  90                  95      


Tyr Ser Glu Glu Ala Asn Asn Leu Ile Glu Glu Cys Glu Gln Ala Glu 
            100                 105                 110         


Arg Leu Gly Ala Val Asp Glu Ser Leu Ser Glu Glu Thr Gln Lys Ala 
        115                 120                 125             


Val Leu Gln Trp Thr Lys His Asp Asp Ser Ser Asp Asn Phe Cys Glu 
    130                 135                 140                 


Ala Asp Asp Ile Gln Ser Pro Glu Ala Glu Tyr Val Asp Leu Leu Leu 
145                 150                 155                 160 


Asn Pro Glu Arg Tyr Thr Gly Tyr Lys Gly Pro Asp Ala Trp Lys Ile 
                165                 170                 175     


Trp Asn Val Ile Tyr Glu Glu Asn Cys Phe Lys Pro Gln Thr Ile Lys 
            180                 185                 190         


Arg Pro Leu Asn Pro Leu Ala Ser Gly Gln Gly Thr Ser Glu Glu Asn 
        195                 200                 205             


Thr Phe Tyr Ser Trp Leu Glu Gly Leu Cys Val Glu Lys Arg Ala Phe 
    210                 215                 220                 


Tyr Arg Leu Ile Ser Gly Leu His Ala Ser Ile Asn Val His Leu Ser 
225                 230                 235                 240 


Ala Arg Tyr Leu Leu Gln Glu Thr Trp Leu Glu Lys Lys Trp Gly His 
                245                 250                 255     


Asn Ile Thr Glu Phe Gln Gln Arg Phe Asp Gly Ile Leu Thr Glu Gly 
            260                 265                 270         


Glu Gly Pro Arg Arg Leu Lys Asn Leu Tyr Phe Leu Tyr Leu Ile Glu 
        275                 280                 285             


Leu Arg Ala Leu Ser Lys Val Leu Pro Phe Phe Glu Arg Pro Asp Phe 
    290                 295                 300                 


Gln Leu Phe Thr Gly Asn Lys Ile Gln Asp Glu Glu Asn Lys Met Leu 
305                 310                 315                 320 


Leu Leu Glu Ile Leu His Glu Ile Lys Ser Phe Pro Leu His Phe Asp 
                325                 330                 335     


Glu Asn Ser Phe Phe Ala Gly Asp Lys Lys Glu Ala His Lys Leu Lys 
            340                 345                 350         


Glu Asp Phe Arg Leu His Phe Arg Asn Ile Ser Arg Ile Met Asp Cys 
        355                 360                 365             


Val Gly Cys Phe Lys Cys Arg Leu Trp Gly Lys Leu Gln Thr Gln Gly 
    370                 375                 380                 


Leu Gly Thr Ala Leu Lys Ile Leu Phe Ser Glu Lys Leu Ile Ala Asn 
385                 390                 395                 400 


Met Pro Glu Ser Gly Pro Ser Tyr Glu Phe His Leu Thr Arg Gln Glu 
                405                 410                 415     


Ile Val Ser Leu Phe Asn Ala Phe Gly Arg Ile Ser Thr Ser Val Lys 
            420                 425                 430         


Glu Leu Glu Asn Phe Arg Asn Leu Leu Gln Asn Ile His 
        435                 440                 445 


<210>  2786
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  2786

Leu Phe Leu Phe Gly Gln Pro Asp Phe Ser Tyr Lys Arg Ser Asn Cys 
1               5                   10                  15      


Lys Pro Ile Pro Val Asn Leu Gln Leu Cys His Gly Ile Glu Tyr Gln 
            20                  25                  30          


Asn Met Arg Leu Pro Asn Leu Leu Gly His Glu Thr Met Lys Glu Val 
        35                  40                  45              


Leu Glu Gln Ala Gly Ala Trp Ile Pro Leu Val Met Lys Gln Cys His 
    50                  55                  60                  


Pro Asp Thr Lys Lys Phe Leu Cys Ser Leu Phe Ala Pro Val Cys Leu 
65                  70                  75                  80  


Asp Asp Leu Asp Glu Thr Ile Gln Pro Cys His Ser Leu Cys Val Gln 
                85                  90                  95      


Val Lys Asp Arg Cys Ala Pro Val Met Ser Ala Phe Gly Phe Pro Trp 
            100                 105                 110         


Pro Asp Met Leu Glu Cys Asp Arg Phe Pro Gln Asp Asn Asp Leu Cys 
        115                 120                 125             


Ile Pro Leu Ala Ser Ser Asp His Leu Leu Pro Ala Thr Glu Glu Ala 
    130                 135                 140                 


Pro Lys Val Cys Glu Ala Cys Lys Asn Lys Asn Asp Asp Asp Asn Asp 
145                 150                 155                 160 


Ile Met Glu Thr Leu Cys Lys Asn Asp Phe Ala Leu Lys Ile Lys Val 
                165                 170                 175     


Lys Glu Ile Thr Tyr Ile Asn Arg Asp Thr Lys Ile Ile Leu Glu Thr 
            180                 185                 190         


Lys Ser Lys Thr Ile Tyr Lys Leu Asn Gly Val Ser Glu Arg Asp Leu 
        195                 200                 205             


Lys Lys Ser Val Leu Trp Leu Lys Asp Ser Leu Gln Cys Thr Cys Glu 
    210                 215                 220                 


Glu Met Asn Asp Ile Asn Ala Pro Tyr Leu Val Met Gly Gln Lys Gln 
225                 230                 235                 240 


Gly Gly Glu Leu Val Ile Thr Ser Val Lys Arg Trp Gln Lys Gly Gln 
                245                 250                 255     


Arg Glu Phe Lys Arg Ile Ser Arg Ser Ile Arg Lys Leu Gln Cys 
            260                 265                 270     


<210>  2787
<211>  159
<212>  PRT
<213>  Homo Sapiens

<400>  2787

Met Glu Glu Pro Thr Ala Val Glu Gly Gln Val Gln Leu Pro Ser Pro 
1               5                   10                  15      


His Gln Gly Ser Leu Arg Lys Ala Val Ala Ala Ala Leu Ala Leu Asp 
            20                  25                  30          


Gly Glu Ser Thr Met Gly His Arg Lys Lys Lys Arg Lys Glu Ser Arg 
        35                  40                  45              


Pro Glu Ser Ile Ile Ile Tyr Arg Ser Asp Asn Glu Lys Thr Asp Glu 
    50                  55                  60                  


Glu Pro Gly Glu Ser Glu Gly Gly Asp Gln Pro Lys Glu Glu Glu Gly 
65                  70                  75                  80  


Asp Asp Phe Leu Asp Tyr Pro Val Asp Asp Asp Met Trp Asn Leu Pro 
                85                  90                  95      


Leu Asp Ser Arg Tyr Val Thr Leu Thr Gly Thr Ile Thr Arg Gly Lys 
            100                 105                 110         


Lys Lys Gly Gln Met Val Asp Ile His Val Thr Leu Thr Glu Lys Glu 
        115                 120                 125             


Leu Gln Glu Leu Thr Lys Pro Lys Glu Ser Ser Arg Glu Thr Thr Pro 
    130                 135                 140                 


Glu Gly Arg Met Ala Cys Gln Met Gly Ala Asp Arg Gly Pro His 
145                 150                 155                 


<210>  2788
<211>  295
<212>  PRT
<213>  Homo Sapiens

<400>  2788

Ala Ile Arg Ile Glu Ala Ala Ser Leu Arg Leu Thr Leu Ser Thr Leu 
1               5                   10                  15      


Arg His Leu Thr Leu Thr Ser Ile Met Lys Ser Lys Arg Lys Thr Asp 
            20                  25                  30          


His Met Glu Arg Thr Ala Ser Val Leu Arg Arg Glu Ile Val Ser Ala 
        35                  40                  45              


Ala Lys Val Cys Gly Ala Ala Ser Glu Ser Pro Ser Val Lys Ser Leu 
    50                  55                  60                  


Arg Leu Leu Val Ala Asp Gln Asp Phe Ser Phe Lys Ala Gly Gln Trp 
65                  70                  75                  80  


Val Asp Phe Phe Ile Pro Gly Val Ser Val Val Gly Gly Phe Ser Ile 
                85                  90                  95      


Cys Ser Ser Pro Arg Leu Leu Glu Gln Glu Arg Val Ile Glu Leu Ala 
            100                 105                 110         


Val Lys Tyr Thr Asn His Pro Pro Ala Leu Trp Val His Asn Thr Cys 
        115                 120                 125             


Thr Leu Asp Cys Glu Val Ala Val Arg Val Gly Gly Glu Phe Phe Phe 
    130                 135                 140                 


Asp Pro Gln Pro Ala Asp Ala Ser Arg Asn Leu Val Leu Ile Ala Gly 
145                 150                 155                 160 


Gly Val Gly Ile Asn Pro Leu Leu Ser Ile Leu Arg His Ala Ala Asp 
                165                 170                 175     


Leu Leu Arg Glu Gln Ala Asn Lys Arg Asn Gly Tyr Glu Ile Gly Thr 
            180                 185                 190         


Ile Lys Leu Phe Tyr Ser Ala Lys Asn Thr Ser Glu Leu Leu Phe Lys 
        195                 200                 205             


Lys Asn Ile Leu Asp Leu Val Asn Glu Phe Pro Glu Lys Ile Ala Cys 
    210                 215                 220                 


Ser Leu His Val Thr Lys Gln Thr Thr Gln Ile Asn Ala Glu Leu Lys 
225                 230                 235                 240 


Pro Tyr Ile Thr Glu Gly Arg Ile Thr Glu Lys Glu Ile Arg Asp His 
                245                 250                 255     


Ile Ser Lys Glu Thr Leu Phe Tyr Ile Cys Gly Pro Pro Pro Met Thr 
            260                 265                 270         


Asp Phe Phe Ser Lys Gln Leu Glu Asn Asn His Val Pro Lys Glu His 
        275                 280                 285             


Ile Cys Phe Glu Lys Trp Trp 
    290                 295 


<210>  2789
<211>  49
<212>  PRT
<213>  Homo Sapiens

<400>  2789

Leu Tyr Leu Leu Ser Thr Arg Leu Pro Arg Gly Arg Arg Leu Gly Ser 
1               5                   10                  15      


Thr Glu Glu Ala Gly Gly Arg Ser Leu Trp Phe Pro Ser Asp Leu Ala 
            20                  25                  30          


Glu Leu Arg Glu Leu Ser Glu Val Leu Arg Glu Tyr Arg Lys Glu His 
        35                  40                  45              


Gln 
    


<210>  2790
<211>  286
<212>  PRT
<213>  Homo Sapiens

<400>  2790

Ala Ser Ala Gly Gln Glu Pro Leu His Asn Glu Glu Leu Ala Gly Ala 
1               5                   10                  15      


Gly Arg Val Ala Gln Pro Gly Pro Leu Glu Pro Glu Glu Pro Arg Ala 
            20                  25                  30          


Gly Gly Arg Pro Arg Arg Arg Arg Asp Leu Gly Ser Arg Leu Gln Ala 
        35                  40                  45              


Gln Arg Arg Ala Gln Arg Val Ala Trp Ala Glu Ala Asp Glu Asn Glu 
    50                  55                  60                  


Glu Glu Ala Val Ile Leu Ala Gln Glu Glu Glu Gly Val Glu Lys Pro 
65                  70                  75                  80  


Ala Glu Thr His Leu Ser Gly Lys Ile Gly Ala Lys Lys Leu Arg Lys 
                85                  90                  95      


Leu Glu Glu Lys Gln Ala Arg Lys Ala Gln Arg Glu Ala Glu Glu Ala 
            100                 105                 110         


Glu Arg Glu Glu Arg Lys Arg Leu Glu Ser Gln Arg Glu Ala Glu Trp 
        115                 120                 125             


Lys Lys Glu Glu Glu Arg Leu Arg Leu Glu Glu Glu Gln Lys Glu Glu 
    130                 135                 140                 


Glu Glu Arg Lys Ala Arg Glu Glu Gln Ala Gln Arg Glu His Glu Glu 
145                 150                 155                 160 


Tyr Leu Lys Leu Lys Glu Ala Phe Val Val Glu Glu Glu Gly Val Gly 
                165                 170                 175     


Glu Thr Met Thr Glu Glu Gln Ser Gln Ser Phe Leu Thr Glu Phe Ile 
            180                 185                 190         


Asn Tyr Ile Lys Gln Ser Lys Val Val Leu Leu Glu Asp Leu Ala Ser 
        195                 200                 205             


Gln Val Gly Leu Arg Thr Gln Asp Thr Ile Asn Arg Ile Gln Asp Leu 
    210                 215                 220                 


Leu Ala Glu Gly Thr Ile Thr Gly Val Ile Asp Asp Arg Gly Lys Phe 
225                 230                 235                 240 


Ile Tyr Ile Thr Pro Glu Glu Leu Ala Ala Val Ala Asn Phe Ile Arg 
                245                 250                 255     


Gln Arg Gly Arg Val Ser Ile Ala Glu Leu Ala Gln Ala Ser Asn Ser 
            260                 265                 270         


Leu Ile Ala Trp Gly Arg Glu Ser Pro Ala Gln Ala Pro Ala 
        275                 280                 285     


<210>  2791
<211>  309
<212>  PRT
<213>  Homo Sapiens

<400>  2791

Ala Ser Ala Ser Tyr Tyr Glu Gln Tyr His Ser Leu Asn Glu Ile Tyr 
1               5                   10                  15      


Ser Trp Ile Glu Phe Ile Thr Glu Arg His Pro Asp Met Leu Thr Lys 
            20                  25                  30          


Ile His Ile Gly Ser Ser Phe Glu Lys Tyr Pro Leu Tyr Val Leu Lys 
        35                  40                  45              


Val Ser Gly Lys Glu Gln Ala Ala Lys Asn Ala Ile Trp Ile Asp Cys 
    50                  55                  60                  


Gly Ile His Ala Arg Glu Trp Ile Ser Pro Ala Phe Cys Leu Trp Phe 
65                  70                  75                  80  


Ile Gly His Ile Thr Gln Phe Tyr Gly Ile Ile Gly Gln Tyr Thr Asn 
                85                  90                  95      


Leu Leu Arg Leu Val Asp Phe Tyr Val Met Pro Val Val Asn Val Asp 
            100                 105                 110         


Gly Tyr Asp Tyr Ser Trp Lys Lys Asn Arg Met Trp Arg Lys Asn Arg 
        115                 120                 125             


Ser Phe Tyr Ala Asn Asn His Cys Ile Gly Thr Asp Leu Asn Arg Asn 
    130                 135                 140                 


Phe Ala Ser Lys His Trp Cys Glu Glu Gly Ala Ser Ser Ser Ser Cys 
145                 150                 155                 160 


Ser Glu Thr Tyr Cys Gly Leu Tyr Pro Glu Ser Glu Pro Glu Val Lys 
                165                 170                 175     


Ala Val Ala Ser Phe Leu Arg Arg Asn Ile Asn Gln Ile Lys Ala Tyr 
            180                 185                 190         


Ile Ser Met His Ser Tyr Ser Gln His Ile Val Phe Pro Tyr Ser Tyr 
        195                 200                 205             


Thr Arg Ser Lys Ser Lys Asp His Glu Glu Leu Ser Leu Val Ala Ser 
    210                 215                 220                 


Glu Ala Val Arg Ala Ile Glu Lys Thr Ser Lys Asn Thr Arg Tyr Thr 
225                 230                 235                 240 


His Gly His Gly Ser Glu Thr Leu Tyr Leu Ala Pro Gly Gly Gly Asp 
                245                 250                 255     


Asp Trp Ile Tyr Asp Leu Gly Ile Lys Tyr Ser Phe Thr Ile Glu Leu 
            260                 265                 270         


Arg Asp Thr Gly Thr Tyr Gly Phe Leu Leu Pro Glu Arg Tyr Ile Lys 
        275                 280                 285             


Pro Thr Cys Arg Glu Ala Phe Ala Ala Val Ser Lys Ile Ala Trp His 
    290                 295                 300                 


Val Ile Arg Asn Val 
305                 


<210>  2792
<211>  289
<212>  PRT
<213>  Homo Sapiens

<400>  2792

Val Glu Val Ala Glu Glu Ser Gly Arg Leu Trp Ser Glu Glu Gln Pro 
1               5                   10                  15      


Ala His Pro Leu Gln Val Gly Ala Val Tyr Leu Gly Glu Glu Glu Leu 
            20                  25                  30          


Leu His Asp Pro Met Gly Gln Asp Arg Ala Ala Glu Glu Ala Asn Ala 
        35                  40                  45              


Val Leu Gly Leu Asp Thr Gln Gly Asp His Met Val Met Leu Ser Val 
    50                  55                  60                  


Ile Pro Gly Glu Ala Glu Asp Lys Val Ser Ser Glu Pro Ser Gly Val 
65                  70                  75                  80  


Thr Cys Gly Ala Gly Gly Ala Glu Asp Ser Arg Cys Asn Val Arg Glu 
                85                  90                  95      


Ser Leu Phe Ser Leu Asp Gly Ala Gly Ala His Phe Pro Asp Arg Glu 
            100                 105                 110         


Glu Glu Tyr Tyr Thr Glu Pro Glu Val Ala Glu Ser Asp Ala Ala Pro 
        115                 120                 125             


Thr Glu Asp Ser Asn Asn Thr Glu Ser Leu Lys Ser Pro Lys Val Asn 
    130                 135                 140                 


Cys Glu Glu Arg Asn Ile Thr Gly Leu Glu Asn Phe Thr Leu Lys Ile 
145                 150                 155                 160 


Leu Asn Met Ser Gln Asp Leu Met Asp Phe Leu Asn Pro Asn Gly Ser 
                165                 170                 175     


Asp Cys Thr Leu Val Leu Phe Tyr Thr Pro Trp Cys Arg Phe Ser Ala 
            180                 185                 190         


Ser Leu Ala Pro His Phe Asn Ser Leu Pro Arg Ala Phe Pro Ala Leu 
        195                 200                 205             


His Phe Leu Ala Leu Asp Ala Ser Gln His Ser Ser Leu Ser Thr Arg 
    210                 215                 220                 


Phe Gly Thr Val Ala Val Pro Asn Ile Leu Leu Phe Gln Gly Ala Lys 
225                 230                 235                 240 


Pro Met Ala Arg Phe Asn His Thr Asp Arg Thr Leu Glu Thr Leu Lys 
                245                 250                 255     


Ile Phe Ile Phe Asn Gln Thr Gly Ile Glu Ala Lys Lys Asn Val Val 
            260                 265                 270         


Val Thr Gln Ala Asp Gln Ile Gly Pro Leu Pro Ser Thr Leu Ile Lys 
        275                 280                 285             


Ser 
    


<210>  2793
<211>  732
<212>  PRT
<213>  Homo Sapiens

<400>  2793

Gln Ser Leu Gly Thr Thr Lys Leu Arg Leu Val Gly Pro Glu Ser Lys 
1               5                   10                  15      


Pro Glu Glu Gly Arg Leu Glu Val Leu His Gln Gly Gln Trp Gly Thr 
            20                  25                  30          


Val Cys Asp Asp Asn Phe Ala Ile Gln Glu Ala Thr Val Ala Cys Arg 
        35                  40                  45              


Gln Leu Gly Phe Glu Ala Ala Leu Thr Trp Ala His Ser Ala Lys Tyr 
    50                  55                  60                  


Gly Gln Gly Glu Gly Pro Ile Trp Leu Asp Asn Val Arg Cys Val Gly 
65                  70                  75                  80  


Thr Glu Ser Ser Leu Asp Gln Cys Gly Ser Asn Gly Trp Gly Val Ser 
                85                  90                  95      


Asp Cys Ser His Ser Glu Asp Val Gly Val Ile Cys His Pro Arg Arg 
            100                 105                 110         


His Arg Gly Tyr Leu Ser Glu Thr Val Ser Asn Ala Leu Gly Pro Gln 
        115                 120                 125             


Gly Arg Arg Leu Glu Glu Val Arg Leu Lys Pro Ile Leu Ala Ser Ala 
    130                 135                 140                 


Lys Gln His Ser Pro Val Thr Glu Gly Ala Val Glu Val Lys Tyr Glu 
145                 150                 155                 160 


Gly His Trp Arg Gln Val Cys Asp Gln Gly Trp Thr Met Asn Asn Ser 
                165                 170                 175     


Arg Val Val Cys Gly Met Leu Gly Phe Pro Ser Glu Val Pro Val Asp 
            180                 185                 190         


Ser His Tyr Tyr Arg Lys Val Trp Asp Leu Lys Met Arg Asp Pro Lys 
        195                 200                 205             


Ser Arg Leu Lys Ser Leu Thr Asn Lys Asn Ser Phe Trp Ile His Gln 
    210                 215                 220                 


Val Thr Cys Leu Gly Thr Glu Pro His Met Ala Asn Cys Gln Val Gln 
225                 230                 235                 240 


Val Ala Pro Ala Arg Gly Lys Leu Arg Pro Ala Cys Pro Gly Gly Met 
                245                 250                 255     


His Ala Val Val Ser Cys Val Ala Gly Pro His Phe Arg Pro Pro Lys 
            260                 265                 270         


Thr Lys Pro Gln Arg Lys Gly Ser Trp Ala Glu Glu Pro Arg Val Arg 
        275                 280                 285             


Leu Arg Ser Gly Ala Gln Val Gly Glu Gly Arg Val Glu Val Leu Met 
    290                 295                 300                 


Asn Arg Gln Trp Gly Thr Val Cys Asp His Arg Trp Asn Leu Ile Ser 
305                 310                 315                 320 


Ala Ser Val Val Cys Arg Gln Leu Gly Phe Gly Ser Ala Arg Glu Ala 
                325                 330                 335     


Leu Phe Gly Ala Arg Leu Gly Gln Gly Leu Gly Pro Ile His Leu Ser 
            340                 345                 350         


Glu Val Arg Cys Arg Gly Tyr Glu Arg Thr Leu Ser Asp Cys Pro Ala 
        355                 360                 365             


Leu Glu Gly Ser Gln Asn Gly Cys Gln His Glu Asn Ala Ala Ala Val 
    370                 375                 380                 


Arg Cys Asn Val Pro Asn Met Gly Phe Gln Asn Gln Val Arg Leu Ala 
385                 390                 395                 400 


Gly Gly Arg Ile Pro Glu Glu Gly Leu Leu Glu Val Gln Val Glu Val 
                405                 410                 415     


Asn Gly Val Pro Arg Trp Gly Ser Val Cys Ser Glu Asn Trp Gly Leu 
            420                 425                 430         


Thr Glu Ala Met Val Ala Cys Arg Gln Leu Gly Leu Gly Phe Ala Ile 
        435                 440                 445             


His Ala Tyr Lys Glu Thr Trp Phe Trp Ser Gly Thr Pro Arg Ala Gln 
    450                 455                 460                 


Glu Val Val Met Ser Gly Val Arg Cys Ser Gly Thr Glu Leu Ala Leu 
465                 470                 475                 480 


Gln Gln Cys Gln Arg His Gly Pro Val His Cys Ser His Gly Gly Gly 
                485                 490                 495     


Arg Phe Leu Ala Gly Val Ser Cys Met Asp Ser Ala Pro Asp Leu Val 
            500                 505                 510         


Met Asn Ala Gln Leu Val Gln Glu Thr Ala Tyr Leu Glu Asp Arg Pro 
        515                 520                 525             


Leu Ser Gln Leu Tyr Cys Ala His Glu Glu Asn Cys Leu Ser Lys Ser 
    530                 535                 540                 


Ala Asp His Met Asp Trp Pro Tyr Gly Tyr Arg Arg Leu Leu Arg Phe 
545                 550                 555                 560 


Ser Thr Gln Ile Tyr Asn Leu Gly Arg Thr Asp Phe Arg Pro Lys Thr 
                565                 570                 575     


Gly Arg Asp Ser Trp Val Trp His Gln Cys His Arg His Tyr His Ser 
            580                 585                 590         


Ile Glu Val Phe Thr His Tyr Asp Leu Leu Thr Leu Asn Gly Ser Lys 
        595                 600                 605             


Val Ala Glu Gly His Lys Ala Ser Phe Cys Leu Glu Asp Thr Asn Cys 
    610                 615                 620                 


Pro Thr Gly Leu Gln Arg Arg Tyr Ala Cys Ala Asn Phe Gly Glu Gln 
625                 630                 635                 640 


Gly Val Thr Val Gly Cys Trp Asp Thr Tyr Arg His Asp Ile Asp Cys 
                645                 650                 655     


Gln Trp Val Asp Ile Thr Asp Val Gly Pro Gly Asn Tyr Ile Phe Gln 
            660                 665                 670         


Val Ile Val Asn Pro His Tyr Glu Val Ala Glu Ser Asp Phe Ser Asn 
        675                 680                 685             


Asn Met Leu Gln Cys Arg Cys Lys Tyr Asp Gly His Arg Val Trp Leu 
    690                 695                 700                 


His Asn Cys His Thr Gly Asn Ser Tyr Pro Ala Asn Ala Glu Leu Ser 
705                 710                 715                 720 


Leu Glu Gln Glu Gln Arg Leu Arg Asn Asn Leu Ile 
                725                 730         


<210>  2794
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  2794

Met Thr Asn Ser Lys Gly Arg Ser Ile Thr Asp Lys Thr Ser Gly Gly 
1               5                   10                  15      


Pro Ser Ser Gly Gly Gly Phe Val Asp Trp Thr Leu Arg Leu Asn Thr 
            20                  25                  30          


Ile Gln Ser Asp Lys Phe Leu Asn Leu Leu Leu Ser Met Val Pro Val 
        35                  40                  45              


Ile Tyr Gln Lys Asn Gln Glu Asp Arg His Lys Lys Ala Asn Gly Ile 
    50                  55                  60                  


Trp Gln Asp Gly Leu Ser Thr Ala Val Gln Thr Phe Ser Asn Arg Ser 
65                  70                  75                  80  


Glu Gln His Met Glu Tyr His Ser Phe Ser Glu Gln Ser Phe His Ala 
                85                  90                  95      


Asn Asn Gly His Ala Ser Ser Ser Cys Ser Gln Lys Tyr Asp Asp Tyr 
            100                 105                 110         


Ala Asn Tyr Asn Tyr Cys Asp Gly Arg Glu Thr Ser Glu Thr Thr Ala 
        115                 120                 125             


Met Leu Gln Asp Glu Asp Ile Ser Ser Asp Gly Asp Glu Asp Ala Ile 
    130                 135                 140                 


Val Glu Val Thr Pro Lys Leu Pro Lys Glu Ser Ser Gly Ile Met Ala 
145                 150                 155                 160 


Leu Gln 
        


<210>  2795
<211>  412
<212>  PRT
<213>  Homo Sapiens

<400>  2795

Leu Gly Ile Trp Arg Ile Val Ile Arg Ile Gln Arg Gly Lys Ser Thr 
1               5                   10                  15      


Ser Ser Ser Ser Thr Pro Thr Glu Phe Cys Arg Asn Gly Gly Thr Trp 
            20                  25                  30          


Glu Asn Gly Arg Cys Ile Cys Thr Glu Glu Trp Lys Gly Leu Arg Cys 
        35                  40                  45              


Thr Ile Ala Asn Phe Cys Glu Asn Ser Thr Tyr Met Gly Phe Thr Phe 
    50                  55                  60                  


Ala Arg Ile Pro Val Gly Arg Tyr Gly Pro Ser Leu Gln Thr Cys Gly 
65                  70                  75                  80  


Lys Asp Thr Pro Asn Ala Gly Asn Pro Met Ala Val Arg Leu Cys Ser 
                85                  90                  95      


Leu Ser Leu Tyr Gly Glu Ile Glu Leu Gln Lys Val Thr Ile Gly Asn 
            100                 105                 110         


Cys Asn Glu Asn Leu Glu Thr Leu Glu Lys Gln Val Lys Asp Val Thr 
        115                 120                 125             


Ala Pro Leu Asn Asn Ile Ser Ser Glu Val Gln Ile Leu Thr Ser Asp 
    130                 135                 140                 


Ala Asn Lys Leu Thr Ala Glu Asn Ile Thr Ser Ala Thr Arg Val Val 
145                 150                 155                 160 


Gly Gln Ile Phe Asn Thr Ser Arg Asn Ala Ser Pro Glu Ala Lys Lys 
                165                 170                 175     


Val Ala Ile Val Thr Val Ser Gln Leu Leu Asp Ala Ser Glu Asp Ala 
            180                 185                 190         


Phe Gln Arg Val Ala Ala Thr Ala Asn Asp Asp Ala Leu Thr Thr Leu 
        195                 200                 205             


Ile Glu Gln Met Glu Thr Tyr Ser Leu Ser Leu Gly Asn Gln Ser Val 
    210                 215                 220                 


Val Glu Pro Asn Ile Ala Ile Gln Ser Ala Asn Phe Ser Ser Glu Asn 
225                 230                 235                 240 


Ala Val Gly Pro Ser Asn Val Arg Phe Ser Val Gln Lys Gly Ala Ser 
                245                 250                 255     


Ser Ser Leu Val Ser Ser Ser Thr Phe Ile His Thr Asn Val Asp Gly 
            260                 265                 270         


Leu Asn Pro Asp Ala Gln Thr Glu Leu Gln Val Leu Leu Asn Met Thr 
        275                 280                 285             


Lys Asn Tyr Thr Lys Thr Cys Gly Phe Val Val Tyr Gln Asn Asp Lys 
    290                 295                 300                 


Leu Phe Gln Ser Lys Thr Phe Thr Ala Lys Ser Asp Phe Ser Gln Lys 
305                 310                 315                 320 


Ile Ile Ser Ser Lys Thr Asp Glu Asn Glu Gln Asp Gln Ser Ala Ser 
                325                 330                 335     


Val Asp Met Val Phe Ser Pro Lys Tyr Asn Gln Lys Glu Phe Gln Leu 
            340                 345                 350         


Tyr Ser Tyr Ala Cys Val Tyr Trp Asn Leu Ser Ala Lys Asp Trp Asp 
        355                 360                 365             


Thr Tyr Gly Cys Gln Lys Asp Lys Gly Thr Asp Gly Phe Leu Arg Cys 
    370                 375                 380                 


Arg Cys Asn His Thr Thr Asn Phe Ala Val Leu Met Thr Phe Lys Lys 
385                 390                 395                 400 


Asp Tyr Gln Tyr Pro Lys Ser Leu Asp Ile Leu Ser 
                405                 410         


<210>  2796
<211>  253
<212>  PRT
<213>  Homo Sapiens

<400>  2796

Tyr Thr Arg Pro Cys Ser Gly Asp Ala Asn Cys Ile Gln Pro Tyr Leu 
1               5                   10                  15      


Ala Arg Arg Pro Lys Leu Gln Leu Ser Val Tyr Thr Thr Thr Arg Ser 
            20                  25                  30          


His Leu Gly Ala Glu Asn Asn Ile Asp Leu Val Leu Asn Val Glu Asp 
        35                  40                  45              


Phe Asp Val Glu Ser Lys Phe Glu Arg Thr Val Asn Val Ser Val Pro 
    50                  55                  60                  


Lys Lys Thr Arg Asn Asn Gly Thr Leu Tyr Ala Tyr Ile Phe Leu His 
65                  70                  75                  80  


His Ala Gly Val Leu Pro Trp His Asp Gly Lys Gln Val His Leu Val 
                85                  90                  95      


Ser Pro Leu Thr Thr Tyr Met Val Pro Lys Pro Glu Glu Ile Asn Leu 
            100                 105                 110         


Leu Thr Gly Glu Ser Asp Thr Gln Gln Ile Glu Ala Glu Lys Lys Pro 
        115                 120                 125             


Thr Ser Ala Leu Asp Glu Pro Val Ser His Trp Arg Pro Arg Leu Ala 
    130                 135                 140                 


Leu Asn Val Met Ala Asp Asn Phe Val Phe Asp Gly Ser Ser Leu Pro 
145                 150                 155                 160 


Ala Asp Val His Arg Tyr Met Lys Met Ile Gln Leu Gly Lys Thr Val 
                165                 170                 175     


His Tyr Leu Pro Ile Leu Phe Ile Asp Gln Leu Ser Asn Arg Val Lys 
            180                 185                 190         


Asp Leu Met Val Ile Asn Arg Ser Thr Thr Glu Leu Pro Leu Thr Val 
        195                 200                 205             


Ser Tyr Asp Lys Val Ser Leu Gly Arg Leu Arg Phe Trp Ile His Met 
    210                 215                 220                 


Gln Asp Ala Val Tyr Ser Leu Gln Gln Phe Gly Phe Ser Glu Lys Asp 
225                 230                 235                 240 


Ala Asp Glu Val Lys Gly Ile Phe Val Asp Thr Asn Leu 
                245                 250             


<210>  2797
<211>  481
<212>  PRT
<213>  Homo Sapiens

<400>  2797

Ser Pro Ser Pro Pro Pro Ala Leu Leu Glu Lys Val Phe Gln Tyr Ile 
1               5                   10                  15      


Asp Leu His Gln Asp Glu Phe Val Gln Thr Leu Lys Glu Trp Val Ala 
            20                  25                  30          


Ile Glu Ser Asp Ser Val Gln Pro Val Pro Arg Phe Arg Gln Glu Leu 
        35                  40                  45              


Phe Arg Met Met Ala Val Ala Ala Asp Thr Leu Gln Arg Leu Gly Ala 
    50                  55                  60                  


Arg Val Ala Ser Val Asp Met Gly Pro Gln Gln Leu Pro Asp Gly Gln 
65                  70                  75                  80  


Ser Leu Pro Ile Pro Pro Val Ile Leu Ala Glu Leu Gly Ser Asp Pro 
                85                  90                  95      


Thr Lys Gly Thr Val Cys Phe Tyr Gly His Leu Asp Val Gln Pro Ala 
            100                 105                 110         


Asp Arg Gly Asp Gly Trp Leu Thr Asp Pro Tyr Val Leu Thr Glu Val 
        115                 120                 125             


Asp Gly Lys Leu Tyr Gly Arg Gly Ala Thr Asp Asn Lys Gly Pro Val 
    130                 135                 140                 


Leu Ala Trp Ile Asn Ala Val Ser Ala Phe Arg Ala Leu Glu Gln Asp 
145                 150                 155                 160 


Leu Pro Val Asn Ile Lys Phe Ile Ile Glu Gly Met Glu Glu Ala Gly 
                165                 170                 175     


Ser Val Ala Leu Glu Glu Leu Val Glu Lys Glu Lys Asp Arg Phe Phe 
            180                 185                 190         


Ser Gly Val Asp Tyr Ile Val Ile Ser Asp Asn Leu Trp Ile Ser Gln 
        195                 200                 205             


Arg Lys Pro Ala Ile Thr Tyr Gly Thr Arg Gly Asn Ser Tyr Phe Met 
    210                 215                 220                 


Val Glu Val Lys Cys Arg Asp Gln Asp Phe His Ser Gly Thr Phe Gly 
225                 230                 235                 240 


Gly Ile Leu His Glu Pro Met Ala Asp Leu Val Ala Leu Leu Gly Ser 
                245                 250                 255     


Leu Val Asp Ser Ser Gly His Ile Leu Val Pro Gly Ile Tyr Asp Glu 
            260                 265                 270         


Val Val Pro Leu Thr Glu Glu Glu Ile Asn Thr Tyr Lys Ala Ile His 
        275                 280                 285             


Leu Asp Leu Glu Glu Tyr Arg Asn Ser Ser Arg Val Glu Lys Phe Leu 
    290                 295                 300                 


Phe Asp Thr Lys Glu Glu Ile Leu Met His Leu Trp Arg Tyr Pro Ser 
305                 310                 315                 320 


Leu Ser Ile His Gly Ile Glu Gly Ala Phe Asp Glu Pro Gly Thr Lys 
                325                 330                 335     


Thr Val Ile Pro Gly Arg Val Ile Gly Lys Phe Ser Ile Arg Leu Val 
            340                 345                 350         


Pro His Met Asn Val Ser Ala Val Glu Lys Gln Val Thr Arg His Leu 
        355                 360                 365             


Glu Asp Val Phe Ser Lys Arg Asn Ser Ser Asn Lys Met Val Val Ser 
    370                 375                 380                 


Met Thr Leu Gly Leu His Pro Trp Ile Ala Asn Ile Asp Asp Thr Gln 
385                 390                 395                 400 


Tyr Leu Ala Ala Lys Arg Ala Ile Arg Thr Val Phe Gly Thr Glu Pro 
                405                 410                 415     


Asp Met Ile Arg Asp Gly Ser Thr Ile Pro Ile Ala Lys Met Phe Gln 
            420                 425                 430         


Glu Ile Val His Lys Ser Val Val Leu Ile Pro Leu Gly Ala Val Asp 
        435                 440                 445             


Asp Gly Glu His Ser Gln Asn Glu Lys Ile Asn Arg Trp Asn Tyr Ile 
    450                 455                 460                 


Glu Gly Thr Lys Leu Phe Ala Ala Phe Phe Leu Glu Met Ala Gln Leu 
465                 470                 475                 480 


His 
    


<210>  2798
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2798

Tyr Ile Leu Gly Arg Cys Thr Val Ala Lys Lys Leu His Asp Gly Gly 
1               5                   10                  15      


Leu Asp Tyr Phe Glu Gly Tyr Ser Leu Glu Asn Trp Val Cys Leu Ala 
            20                  25                  30          


Tyr Phe Glu Ser Lys Phe Asn Pro Met Ala Ile Tyr Glu Asn Thr Arg 
        35                  40                  45              


Glu Gly Tyr Thr Gly Phe Gly Leu Phe Gln Met Arg Gly Ser Asp Trp 
    50                  55                  60                  


Cys Gly Asp His Gly Arg Asn Arg Cys His Met Ser Cys Ser Ala Leu 
65                  70                  75                  80  


Leu Asn Pro Asn Leu Glu Lys Thr Ile Lys Cys Ala Lys Thr Ile Val 
                85                  90                  95      


Lys Gly Lys Glu Gly Met Gly Ala Trp Pro Thr Trp Ser Arg Tyr Cys 
            100                 105                 110         


Gln Tyr Ser Asp Thr Leu Ala Arg Trp Leu Asp Gly Cys Lys Leu 
        115                 120                 125         


<210>  2799
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  2799

Met Arg Trp Ala Ala Ala Thr Leu Arg Gly Lys Ala Arg Pro Arg Gly 
1               5                   10                  15      


Arg Ala Gly Val Thr Thr Pro Ala Pro Gly Asn Arg Thr Gly Thr Cys 
            20                  25                  30          


Ala Lys Leu Arg Leu Pro Pro Gln Ala Thr Phe Gln Val Leu Arg Gly 
        35                  40                  45              


Asn Gly Ala Ser Val Gly Thr Val Leu Met Phe Arg Cys Pro Ser Asn 
    50                  55                  60                  


His Gln Met Val Gly Ser Gly Leu Leu Thr Cys Thr Trp Lys Gly Ser 
65                  70                  75                  80  


Ile Ala Glu Trp Ser Ser Gly Ser Pro Val Cys Lys Leu Val Pro Pro 
                85                  90                  95      


His Glu Thr Phe Gly Phe Lys 
            100             


<210>  2800
<211>  365
<212>  PRT
<213>  Homo Sapiens

<400>  2800

Thr Val Tyr Phe Gln Glu Glu Phe Leu Asp Gly Glu His Trp Arg Asn 
1               5                   10                  15      


Arg Trp Leu Gln Ser Thr Asn Asp Ser Arg Phe Gly His Phe Arg Leu 
            20                  25                  30          


Ser Ser Gly Lys Phe Tyr Gly His Lys Glu Lys Asp Lys Gly Leu Gln 
        35                  40                  45              


Thr Thr Gln Asn Gly Arg Phe Tyr Ala Ile Ser Ala Arg Phe Lys Pro 
    50                  55                  60                  


Phe Ser Asn Lys Gly Lys Thr Leu Val Ile Gln Tyr Thr Val Lys His 
65                  70                  75                  80  


Glu Gln Lys Met Asp Cys Gly Gly Gly Tyr Ile Lys Val Phe Pro Ala 
                85                  90                  95      


Asp Ile Asp Gln Lys Asn Leu Asn Gly Lys Ser Gln Tyr Tyr Ile Met 
            100                 105                 110         


Phe Gly Pro Asp Ile Cys Gly Phe Asp Ile Lys Lys Val His Val Ile 
        115                 120                 125             


Leu His Phe Lys Asn Lys Tyr His Glu Asn Lys Lys Leu Ile Arg Cys 
    130                 135                 140                 


Lys Val Asp Gly Phe Thr His Leu Tyr Thr Leu Ile Leu Arg Pro Asp 
145                 150                 155                 160 


Leu Ser Tyr Asp Val Lys Ile Asp Gly Gln Ser Ile Glu Ser Gly Ser 
                165                 170                 175     


Ile Glu Tyr Asp Trp Asn Leu Thr Ser Leu Lys Lys Glu Thr Ser Pro 
            180                 185                 190         


Ala Glu Ser Lys Asp Trp Glu Gln Thr Lys Asp Asn Lys Ala Gln Asp 
        195                 200                 205             


Trp Glu Lys His Phe Leu Asp Ala Ser Thr Ser Lys Gln Ser Asp Trp 
    210                 215                 220                 


Asn Gly Asp Leu Asp Gly Asp Trp Pro Ala Pro Met Leu Gln Lys Pro 
225                 230                 235                 240 


Pro Tyr Gln Asp Gly Leu Lys Pro Glu Gly Ile His Lys Asp Val Trp 
                245                 250                 255     


Leu His Arg Lys Met Lys Asn Thr Asp Tyr Leu Thr Gln Tyr Asp Leu 
            260                 265                 270         


Ser Glu Phe Glu Asn Ile Gly Ala Ile Gly Leu Glu Leu Trp Gln Val 
        275                 280                 285             


Arg Ser Gly Thr Ile Phe Asp Asn Phe Leu Ile Thr Asp Asp Glu Glu 
    290                 295                 300                 


Tyr Ala Asp Asn Phe Gly Lys Ala Thr Trp Gly Glu Thr Lys Gly Pro 
305                 310                 315                 320 


Glu Arg Glu Met Asp Ala Ile Gln Ala Lys Glu Glu Met Lys Lys Ala 
                325                 330                 335     


Arg Glu Glu Glu Glu Glu Glu Leu Leu Ser Gly Lys Ile Asn Arg His 
            340                 345                 350         


Glu His Tyr Phe Asn Gln Phe His Arg Arg Asn Glu Leu 
        355                 360                 365 


<210>  2801
<211>  270
<212>  PRT
<213>  Homo Sapiens

<400>  2801

Val Pro Thr Ile Leu Pro Leu Gly Leu Ala Pro Asp Thr Phe Asp Asp 
1               5                   10                  15      


Thr Tyr Val Gly Cys Val Glu Glu Met Glu Glu Lys Ala Ala Pro Leu 
            20                  25                  30          


Leu Lys Glu Glu Met Ala His His Ala Leu Leu Arg Glu Ser Trp Glu 
        35                  40                  45              


Ala Ala Gln Glu Thr Trp Glu Asp Lys Arg Arg Gly Leu Thr Leu Pro 
    50                  55                  60                  


Pro Gly Phe Lys Ala Gln Asn Gly Ile Ala Ile Met Val Tyr Thr Asn 
65                  70                  75                  80  


Ser Ser Asn Thr Leu Tyr Trp Glu Leu Asn Gln Ala Val Arg Thr Gly 
                85                  90                  95      


Gly Gly Ser Arg Glu Leu Tyr Met Arg His Phe Pro Phe Lys Ala Leu 
            100                 105                 110         


His Phe Tyr Leu Ile Arg Ala Leu Gln Leu Leu Arg Gly Ser Gly Gly 
        115                 120                 125             


Cys Ser Arg Gly Pro Gly Glu Val Val Phe Arg Gly Val Gly Ser Leu 
    130                 135                 140                 


Arg Phe Glu Pro Lys Arg Leu Gly Asp Ser Val Arg Leu Gly Gln Phe 
145                 150                 155                 160 


Ala Ser Ser Ser Leu Asp Lys Ala Val Ala His Arg Phe Gly Asn Ala 
                165                 170                 175     


Thr Leu Phe Ser Leu Thr Thr Cys Phe Gly Ala Pro Ile Gln Ala Phe 
            180                 185                 190         


Ser Val Phe Pro Lys Glu Arg Glu Val Leu Ile Pro Pro His Glu Val 
        195                 200                 205             


Phe Leu Val Thr Arg Phe Ser Gln Asp Gly Ala Gln Ser Leu Val Thr 
    210                 215                 220                 


Leu Trp Ser Tyr Asn Gln Thr Cys Ser His Phe Asn Cys Ala Tyr Leu 
225                 230                 235                 240 


Gly Gly Glu Lys Arg Arg Gly Cys Val Ser Ala Pro Gly Ala Leu Gly 
                245                 250                 255     


Thr Gly Asp Leu His Met Thr Lys Arg His Leu Gln Gln Pro 
            260                 265                 270 


<210>  2802
<211>  324
<212>  PRT
<213>  Homo Sapiens

<400>  2802

Trp Asp Thr Pro Thr Ile Val Ser Arg Lys Glu Trp Gly Ala Arg Pro 
1               5                   10                  15      


Leu Ala Cys Arg Ala Leu Leu Thr Leu Pro Val Ala Tyr Ile Ile Thr 
            20                  25                  30          


Asp Gln Leu Pro Gly Met Gln Cys Gln Gln Gln Ser Val Cys Ser Gln 
        35                  40                  45              


Met Leu Arg Gly Leu Gln Ser His Ser Val Tyr Thr Ile Gly Trp Cys 
    50                  55                  60                  


Asp Val Ala Tyr Asn Phe Leu Val Gly Asp Asp Gly Arg Val Tyr Glu 
65                  70                  75                  80  


Gly Val Gly Trp Asn Ile Gln Gly Leu His Thr Gln Gly Tyr Asn Asn 
                85                  90                  95      


Ile Ser Leu Gly Ile Ala Phe Phe Gly Asn Lys Ile Gly Ser Ser Pro 
            100                 105                 110         


Ser Pro Ala Ala Leu Ser Ala Ala Glu Gly Leu Ile Ser Tyr Ala Ile 
        115                 120                 125             


Gln Lys Gly His Leu Ser Pro Arg Tyr Ile Gln Pro Leu Leu Leu Lys 
    130                 135                 140                 


Glu Glu Thr Cys Leu Asp Pro Gln His Pro Val Met Pro Arg Lys Val 
145                 150                 155                 160 


Cys Pro Asn Ile Ile Lys Arg Ser Ala Trp Glu Ala Arg Glu Thr His 
                165                 170                 175     


Cys Pro Lys Met Asn Leu Pro Ala Lys Tyr Val Ile Ile Ile His Thr 
            180                 185                 190         


Ala Gly Thr Ser Cys Thr Val Ser Thr Asp Cys Gln Thr Val Val Arg 
        195                 200                 205             


Asn Ile Gln Ser Phe His Met Asp Thr Arg Asn Phe Cys Asp Ile Gly 
    210                 215                 220                 


Tyr His Phe Leu Val Gly Gln Asp Gly Gly Val Tyr Glu Gly Val Gly 
225                 230                 235                 240 


Trp His Ile Gln Gly Ser His Thr Tyr Gly Phe Asn Asp Ile Ala Leu 
                245                 250                 255     


Gly Ile Ala Phe Ile Gly Tyr Phe Val Glu Lys Pro Pro Asn Ala Ala 
            260                 265                 270         


Ala Leu Glu Ala Ala Gln Asp Leu Ile Gln Cys Ala Val Val Glu Gly 
        275                 280                 285             


Tyr Leu Thr Pro Asn Tyr Leu Leu Met Gly His Ser Asp Val Val Asn 
    290                 295                 300                 


Ile Leu Ser Pro Gly Gln Ala Leu Tyr Asn Ile Ile Ser Thr Trp Pro 
305                 310                 315                 320 


His Phe Lys His 
                


<210>  2803
<211>  105
<212>  PRT
<213>  Homo Sapiens

<400>  2803

Ser Gln His Leu Arg Gly His Ala Gly His His Gln Ile Lys Gln Gly 
1               5                   10                  15      


Thr Cys Glu Val Val Ala Val His Arg Cys Cys Asn Lys Asn Arg Ile 
            20                  25                  30          


Glu Glu Arg Ser Gln Thr Val Lys Cys Ser Cys Phe Pro Gly Gln Val 
        35                  40                  45              


Ala Gly Thr Thr Arg Ala Gln Pro Ser Cys Val Glu Ala Ser Ile Val 
    50                  55                  60                  


Ile Gln Lys Trp Trp Cys His Met Asn Pro Cys Leu Glu Gly Glu Asp 
65                  70                  75                  80  


Cys Lys Val Leu Pro Asp Tyr Ser Gly Trp Ser Cys Ser Ser Gly Asn 
                85                  90                  95      


Lys Val Lys Thr Thr Lys Val Thr Arg 
            100                 105 


<210>  2804
<211>  481
<212>  PRT
<213>  Homo Sapiens

<400>  2804

Met Ser Thr Leu Cys Pro Pro Pro Ser Pro Ala Val Ala Lys Thr Glu 
1               5                   10                  15      


Ile Ala Leu Ser Gly Lys Ser Pro Leu Leu Ala Ala Thr Phe Ala Tyr 
            20                  25                  30          


Trp Asp Asn Ile Leu Gly Pro Arg Val Arg His Ile Trp Ala Pro Lys 
        35                  40                  45              


Thr Glu Gln Val Leu Leu Ser Asp Gly Glu Ile Thr Phe Leu Ala Asn 
    50                  55                  60                  


His Thr Leu Asn Gly Glu Ile Leu Arg Asn Ala Glu Ser Gly Ala Ile 
65                  70                  75                  80  


Asp Val Lys Phe Phe Val Leu Ser Glu Lys Gly Val Ile Ile Val Ser 
                85                  90                  95      


Leu Ile Phe Asp Gly Asn Trp Asn Gly Asp Arg Ser Thr Tyr Gly Leu 
            100                 105                 110         


Ser Ile Ile Leu Pro Gln Thr Glu Leu Ser Phe Tyr Leu Pro Leu His 
        115                 120                 125             


Arg Val Cys Val Asp Arg Leu Thr His Ile Ile Arg Lys Gly Arg Ile 
    130                 135                 140                 


Trp Met His Lys Glu Arg Gln Glu Asn Val Gln Lys Ile Ile Leu Glu 
145                 150                 155                 160 


Gly Thr Glu Arg Met Glu Asp Gln Gly Gln Ser Ile Ile Pro Met Leu 
                165                 170                 175     


Thr Gly Glu Val Ile Pro Val Met Glu Leu Leu Ser Ser Met Lys Ser 
            180                 185                 190         


His Ser Val Pro Glu Glu Ile Asp Ile Ala Asp Thr Val Leu Asn Asp 
        195                 200                 205             


Asp Asp Ile Gly Asp Ser Cys His Glu Gly Phe Leu Leu Asn Ala Ile 
    210                 215                 220                 


Ser Ser His Leu Gln Thr Cys Gly Cys Ser Val Val Val Gly Ser Ser 
225                 230                 235                 240 


Ala Glu Lys Val Asn Lys Ile Val Arg Thr Leu Cys Leu Phe Leu Thr 
                245                 250                 255     


Pro Ala Glu Arg Lys Cys Ser Arg Leu Cys Glu Ala Glu Ser Ser Phe 
            260                 265                 270         


Lys Tyr Glu Ser Gly Leu Phe Val Gln Gly Leu Leu Lys Asp Ser Thr 
        275                 280                 285             


Gly Ser Phe Val Leu Pro Phe Arg Gln Val Met Tyr Ala Pro Tyr Pro 
    290                 295                 300                 


Thr Thr His Ile Asp Val Asp Val Asn Thr Val Lys Gln Met Pro Pro 
305                 310                 315                 320 


Cys His Glu His Ile Tyr Asn Gln Arg Arg Tyr Met Arg Ser Glu Leu 
                325                 330                 335     


Thr Ala Phe Trp Arg Ala Thr Ser Glu Glu Asp Met Ala Gln Asp Thr 
            340                 345                 350         


Ile Ile Tyr Thr Asp Glu Ser Phe Thr Pro Asp Leu Asn Ile Phe Gln 
        355                 360                 365             


Asp Val Leu His Arg Asp Thr Leu Val Lys Ala Phe Leu Asp Gln Val 
    370                 375                 380                 


Phe Gln Leu Lys Pro Gly Leu Ser Leu Arg Ser Thr Phe Leu Ala Gln 
385                 390                 395                 400 


Phe Leu Leu Val Leu His Arg Lys Ala Leu Thr Leu Ile Lys Tyr Ile 
                405                 410                 415     


Glu Asp Asp Thr Gln Lys Gly Lys Lys Pro Phe Lys Ser Leu Arg Asn 
            420                 425                 430         


Leu Lys Ile Asp Leu Asp Leu Thr Ala Glu Gly Asp Leu Asn Ile Ile 
        435                 440                 445             


Met Ala Leu Ala Glu Lys Ile Lys Pro Gly Leu His Ser Phe Ile Phe 
    450                 455                 460                 


Gly Arg Pro Phe Tyr Thr Ser Val Gln Glu Arg Asp Val Leu Met Thr 
465                 470                 475                 480 


Phe 
    


<210>  2805
<211>  508
<212>  PRT
<213>  Homo Sapiens

<400>  2805

Gln Leu Arg Pro Arg Glu Arg Pro Arg Gly Cys Pro Cys Thr Gly Arg 
1               5                   10                  15      


Ala Ser Ser Leu Ala Arg Asp Ser Ala Ala Ala Ala Ser Asp Pro Gly 
            20                  25                  30          


Thr Ile Val His Asn Phe Ser Arg Thr Glu Pro Arg Thr Glu Pro Ala 
        35                  40                  45              


Gly Gly Ser His Ser Gly Ser Ser Ser Lys Leu Gln Ala Leu Phe Ala 
    50                  55                  60                  


His Pro Leu Tyr Asn Val Pro Glu Glu Pro Pro Leu Leu Gly Ala Glu 
65                  70                  75                  80  


Asp Ser Leu Leu Ala Ser Gln Glu Ala Leu Arg Tyr Tyr Arg Arg Lys 
                85                  90                  95      


Val Ala Arg Trp Asn Arg Arg His Lys Met Tyr Arg Glu Gln Met Asn 
            100                 105                 110         


Leu Thr Ser Leu Asp Pro Pro Leu Gln Leu Arg Leu Glu Ala Ser Trp 
        115                 120                 125             


Val Gln Phe His Leu Gly Ile Asn Arg His Gly Leu Tyr Ser Arg Ser 
    130                 135                 140                 


Ser Pro Val Val Ser Lys Leu Leu Gln Asp Met Arg His Phe Pro Thr 
145                 150                 155                 160 


Ile Ser Ala Asp Tyr Ser Gln Asp Glu Lys Ala Leu Leu Gly Ala Cys 
                165                 170                 175     


Asp Cys Thr Gln Ile Val Lys Pro Ser Gly Val His Leu Lys Leu Val 
            180                 185                 190         


Leu Arg Phe Ser Asp Phe Gly Lys Ala Met Phe Lys Pro Met Arg Gln 
        195                 200                 205             


Gln Arg Asp Glu Glu Thr Pro Val Asp Phe Phe Tyr Phe Ile Asp Phe 
    210                 215                 220                 


Gln Arg His Asn Ala Glu Ile Ala Ala Phe His Leu Asp Arg Ile Leu 
225                 230                 235                 240 


Asp Phe Arg Arg Val Pro Pro Thr Val Gly Arg Ile Val Asn Val Thr 
                245                 250                 255     


Lys Glu Ile Leu Glu Val Thr Lys Asn Glu Ile Leu Gln Ser Val Phe 
            260                 265                 270         


Phe Val Ser Pro Ala Ser Asn Val Cys Phe Phe Ala Lys Cys Pro Tyr 
        275                 280                 285             


Met Cys Lys Thr Glu Tyr Ala Val Cys Gly Asn Pro His Leu Leu Glu 
    290                 295                 300                 


Gly Ser Leu Ser Ala Phe Leu Pro Ser Leu Asn Leu Ala Pro Arg Leu 
305                 310                 315                 320 


Ser Val Pro Asn Pro Trp Ile Arg Ser Tyr Thr Leu Ala Gly Lys Glu 
                325                 330                 335     


Glu Trp Glu Val Asn Pro Leu Tyr Cys Asp Thr Val Lys Gln Ile Tyr 
            340                 345                 350         


Pro Tyr Asn Asn Ser Gln Arg Leu Leu Asn Val Ile Asp Met Ala Ile 
        355                 360                 365             


Phe Asp Phe Leu Ile Gly Asn Met Asp Arg His His Tyr Glu Met Phe 
    370                 375                 380                 


Thr Lys Phe Gly Asp Asp Gly Phe Leu Ile His Leu Asp Asn Ala Arg 
385                 390                 395                 400 


Gly Phe Gly Arg His Ser His Asp Glu Ile Ser Ile Leu Ser Pro Leu 
                405                 410                 415     


Ser Gln Cys Cys Met Ile Lys Lys Lys Thr Leu Leu His Leu Gln Leu 
            420                 425                 430         


Leu Ala Gln Ala Asp Tyr Arg Leu Ser Asp Val Met Arg Glu Ser Leu 
        435                 440                 445             


Leu Glu Asp Gln Leu Ser Pro Val Leu Thr Glu Pro His Leu Leu Ala 
    450                 455                 460                 


Leu Asp Arg Arg Leu Gln Thr Ile Leu Arg Thr Val Glu Gly Cys Ile 
465                 470                 475                 480 


Val Ala His Gly Gln Gln Ser Val Ile Val Asp Gly Pro Val Glu Gln 
                485                 490                 495     


Ser Ala Pro Asp Ser Gly Gln Ala Asn Leu Thr Ser 
            500                 505             


<210>  2806
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  2806

Ser Leu Ser Pro Ser Gln Pro Leu Ser Phe Gln Cys Leu Lys Ala Pro 
1               5                   10                  15      


Ala Thr Leu Thr Trp Glu Asp Glu Lys Gln Gln Arg Trp Gly Gln Pro 
            20                  25                  30          


His Gly Pro Val Ser Ser Pro Leu Leu Gly Asp His Arg Cys Leu Val 
        35                  40                  45              


Pro Phe Arg Asp Leu Asn Pro Ser Ser Glu Val Asn Thr Ala Asn Leu 
    50                  55                  60                  


Leu Glu Ser Pro Ser Ser Leu Leu Leu Thr Ser Cys Tyr Ile Cys Ser 
65                  70                  75                  80  


Tyr Phe Ser Phe Tyr Ile Leu Gly Glu Lys Arg Cys His Ser Leu Lys 
                85                  90                  95      


Arg Leu Arg Tyr Ser Val Cys Cys Lys Val Cys Pro Asn Phe Cys Ala 
            100                 105                 110         


Cys Gly Lys Glu Asn Val Ser Gly Thr Gly Gln Val Cys Thr Gly Val 
        115                 120                 125             


His Val Gly Ala Lys Glu Gln Glu Glu Pro Gly Gly Thr Gln Ala Leu 
    130                 135                 140                 


Arg Ser Cys Gly Ile Tyr Cys Leu Glu Glu Arg Thr Asp Lys Ala Ser 
145                 150                 155                 160 


His Glu Glu Cys Arg Glu Arg Ser Thr Leu Gly Arg Pro Gln Cys Thr 
                165                 170                 175     


Gly Leu Thr Pro Ser Leu Ala Gly Glu Ser Pro Cys Pro Arg Leu Leu 
            180                 185                 190         


Pro Gly Ser Pro Thr Val Arg His Leu Ile Ala Ser Ser Cys Pro Gly 
        195                 200                 205             


Leu Ser Asp Pro Leu Pro Leu Pro Pro Gly Thr Leu Pro Leu Gly Ser 
    210                 215                 220                 


<210>  2807
<211>  131
<212>  PRT
<213>  Homo Sapiens

<400>  2807

Val Pro Ala Pro Lys Val Pro Ile Lys Met Gln Val Lys His Trp Pro 
1               5                   10                  15      


Ser Glu Gln Asp Pro Glu Lys Ala Trp Gly Ala Arg Val Val Glu Pro 
            20                  25                  30          


Pro Glu Lys Asp Asp Gln Leu Val Val Leu Phe Pro Val Gln Lys Pro 
        35                  40                  45              


Lys Leu Leu Thr Thr Glu Glu Lys Pro Arg Gly Gln Gly Arg Gly Pro 
    50                  55                  60                  


Ile Leu Pro Gly Thr Lys Ala Trp Met Glu Thr Glu Asp Thr Leu Gly 
65                  70                  75                  80  


Arg Val Leu Ser Pro Glu Pro Asp His Asp Ser Leu Tyr His Pro Pro 
                85                  90                  95      


Pro Glu Glu Asp Gln Gly Glu Glu Arg Pro Arg Leu Trp Val Met Pro 
            100                 105                 110         


Asn His Gln Val Leu Leu Gly Pro Glu Glu Asp Gln Asp His Ile Tyr 
        115                 120                 125             


His Pro Gln 
    130     


<210>  2808
<211>  935
<212>  PRT
<213>  Homo Sapiens

<400>  2808

Glu Asp Gly Glu Val Arg Ser Ser Cys Arg Thr Ala Pro Thr Asp Leu 
1               5                   10                  15      


Val Phe Ile Leu Asp Gly Ser Tyr Ser Val Gly Pro Glu Asn Phe Glu 
            20                  25                  30          


Ile Val Lys Lys Trp Leu Val Asn Ile Thr Lys Asn Phe Asp Ile Gly 
        35                  40                  45              


Pro Lys Phe Ile Gln Val Gly Val Val Gln Tyr Ser Asp Tyr Pro Val 
    50                  55                  60                  


Leu Glu Ile Pro Leu Gly Ser Tyr Asp Ser Gly Glu His Leu Thr Ala 
65                  70                  75                  80  


Ala Val Glu Ser Ile Leu Tyr Leu Gly Gly Asn Thr Lys Thr Gly Lys 
                85                  90                  95      


Ala Ile Gln Phe Ala Leu Asp Tyr Leu Phe Ala Lys Ser Ser Arg Phe 
            100                 105                 110         


Leu Thr Lys Ile Ala Val Val Leu Thr Asp Gly Lys Ser Gln Asp Asp 
        115                 120                 125             


Val Lys Asp Ala Ala Gln Ala Ala Arg Asp Ser Lys Ile Thr Leu Phe 
    130                 135                 140                 


Ala Ile Gly Val Gly Ser Glu Thr Glu Asp Ala Glu Leu Arg Ala Ile 
145                 150                 155                 160 


Ala Asn Lys Pro Ser Ser Thr Tyr Val Phe Tyr Val Glu Asp Tyr Ile 
                165                 170                 175     


Ala Ile Ser Lys Ile Arg Glu Val Met Lys Gln Lys Leu Cys Glu Glu 
            180                 185                 190         


Ser Val Cys Pro Thr Arg Ile Pro Val Ala Ala Arg Asp Glu Arg Gly 
        195                 200                 205             


Phe Asp Ile Leu Leu Gly Leu Asp Val Asn Lys Lys Val Lys Lys Arg 
    210                 215                 220                 


Ile Gln Leu Ser Pro Lys Lys Ile Lys Gly Tyr Glu Val Thr Ser Lys 
225                 230                 235                 240 


Val Asp Leu Ser Glu Leu Thr Ser Asn Val Phe Pro Glu Gly Leu Pro 
                245                 250                 255     


Pro Ser Tyr Val Phe Val Ser Thr Gln Arg Phe Lys Val Lys Lys Ile 
            260                 265                 270         


Trp Asp Leu Trp Arg Ile Leu Thr Ile Asp Gly Arg Pro Gln Ile Ala 
        275                 280                 285             


Val Thr Leu Asn Gly Val Asp Lys Ile Leu Leu Phe Thr Thr Thr Ser 
    290                 295                 300                 


Val Ile Asn Gly Ser Gln Val Val Thr Phe Ala Asn Pro Gln Val Lys 
305                 310                 315                 320 


Thr Leu Phe Asp Glu Gly Trp His Gln Ile Arg Leu Leu Val Thr Glu 
                325                 330                 335     


Gln Asp Val Thr Leu Tyr Ile Asp Asp Gln Gln Ile Glu Asn Lys Pro 
            340                 345                 350         


Leu His Pro Val Leu Gly Ile Leu Ile Asn Gly Gln Thr Gln Ile Gly 
        355                 360                 365             


Lys Tyr Ser Gly Lys Glu Glu Thr Val Gln Phe Asp Val Gln Lys Leu 
    370                 375                 380                 


Arg Ile Tyr Cys Asp Pro Glu Gln Asn Asn Arg Glu Thr Ala Cys Glu 
385                 390                 395                 400 


Ile Pro Gly Phe Asn Gly Glu Cys Leu Asn Gly Pro Ser Asp Val Gly 
                405                 410                 415     


Ser Thr Pro Ala Pro Cys Ile Cys Pro Pro Gly Lys Pro Gly Leu Gln 
            420                 425                 430         


Gly Pro Lys Gly Asp Pro Gly Leu Pro Gly Asn Pro Gly Tyr Pro Gly 
        435                 440                 445             


Gln Pro Gly Gln Asp Gly Lys Pro Gly Tyr Gln Gly Ile Ala Gly Thr 
    450                 455                 460                 


Pro Gly Val Pro Gly Ser Pro Gly Ile Gln Gly Ala Arg Gly Leu Pro 
465                 470                 475                 480 


Gly Tyr Lys Gly Glu Pro Gly Arg Asp Gly Asp Lys Gly Asp Arg Gly 
                485                 490                 495     


Leu Pro Gly Phe Pro Gly Leu His Gly Met Pro Gly Ser Lys Gly Glu 
            500                 505                 510         


Met Gly Ala Lys Gly Asp Lys Gly Ser Pro Gly Phe Tyr Gly Lys Lys 
        515                 520                 525             


Gly Ala Lys Gly Glu Lys Gly Asn Ala Gly Phe Pro Gly Leu Pro Gly 
    530                 535                 540                 


Pro Ala Gly Glu Pro Gly Arg His Gly Lys Asp Gly Leu Met Gly Ser 
545                 550                 555                 560 


Pro Gly Phe Lys Gly Glu Ala Gly Ser Pro Gly Ala Pro Gly Gln Asp 
                565                 570                 575     


Gly Thr Arg Gly Glu Pro Gly Ile Pro Gly Phe Pro Gly Asn Arg Gly 
            580                 585                 590         


Leu Met Gly Gln Lys Gly Glu Ile Gly Pro Pro Gly Gln Gln Gly Lys 
        595                 600                 605             


Lys Gly Ala Pro Gly Met Pro Gly Leu Met Gly Ser Asn Gly Ser Pro 
    610                 615                 620                 


Gly Gln Pro Gly Thr Pro Gly Ser Lys Gly Ser Lys Gly Glu Pro Gly 
625                 630                 635                 640 


Ile Gln Gly Met Pro Gly Ala Ser Gly Leu Lys Gly Glu Pro Gly Ala 
                645                 650                 655     


Thr Gly Ser Pro Gly Glu Pro Gly Tyr Met Gly Leu Pro Gly Ile Gln 
            660                 665                 670         


Gly Lys Lys Gly Asp Lys Gly Asn Gln Gly Glu Lys Gly Ile Gln Gly 
        675                 680                 685             


Gln Lys Gly Glu Asn Gly Arg Gln Gly Ile Pro Gly Gln Gln Gly Ile 
    690                 695                 700                 


Gln Gly His His Gly Ala Lys Gly Glu Arg Gly Glu Lys Gly Glu Pro 
705                 710                 715                 720 


Gly Val Arg Gly Ala Ile Gly Ser Lys Gly Glu Ser Gly Val Asp Gly 
                725                 730                 735     


Leu Met Gly Pro Ala Gly Pro Lys Gly Gln Pro Gly Asp Pro Gly Pro 
            740                 745                 750         


Gln Gly Pro Pro Gly Leu Asp Gly Lys Pro Gly Arg Glu Phe Ser Glu 
        755                 760                 765             


Gln Phe Ile Arg Gln Val Cys Thr Asp Val Ile Arg Ala Gln Leu Pro 
    770                 775                 780                 


Val Leu Leu Gln Ser Gly Arg Ile Arg Asn Cys Asp His Cys Leu Ser 
785                 790                 795                 800 


Gln His Gly Ser Pro Gly Ile Pro Gly Pro Pro Gly Pro Ile Gly Pro 
                805                 810                 815     


Glu Gly Pro Arg Gly Leu Pro Gly Leu Pro Gly Arg Asp Gly Val Pro 
            820                 825                 830         


Gly Leu Val Gly Val Pro Gly Arg Pro Gly Val Arg Gly Leu Lys Gly 
        835                 840                 845             


Leu Pro Gly Arg Asn Gly Glu Lys Gly Ser Gln Gly Phe Gly Tyr Pro 
    850                 855                 860                 


Gly Glu Gln Gly Pro Pro Gly Pro Pro Gly Pro Glu Gly Pro Pro Gly 
865                 870                 875                 880 


Ile Ser Lys Glu Gly Pro Pro Gly Asp Pro Gly Leu Pro Gly Lys Asp 
                885                 890                 895     


Gly Asp His Gly Lys Pro Gly Ile Gln Gly Gln Pro Gly Pro Pro Gly 
            900                 905                 910         


Ile Cys Asp Pro Ser Leu Cys Phe Ser Val Ile Ala Arg Arg Asp Pro 
        915                 920                 925             


Phe Arg Lys Gly Pro Asn Tyr 
    930                 935 


<210>  2809
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  2809

Gln Ile Ser Pro Lys Glu Gly Trp Gln Val Tyr Ser Ser Ala Gln Asp 
1               5                   10                  15      


Pro Asp Gly Arg Cys Ile Cys Thr Val Val Ala Pro Glu Gln Asn Leu 
            20                  25                  30          


Cys Ser Arg Asp Ala Lys Ser Arg Gln Leu Arg Lys Leu Leu Glu Lys 
        35                  40                  45              


Val Gln Asn Met Ser Gln Ser Ile Glu Val Leu Asn Leu Arg Thr Gln 
    50                  55                  60                  


Arg Asp Phe Gln Tyr Val Leu Lys Met Glu Thr Gln Met Lys Gly Leu 
65                  70                  75                  80  


Lys Ala Lys Phe Arg Gln Ile Glu Asp Asp Arg Lys Thr Leu Met Thr 
                85                  90                  95      


Lys His Phe Gln Glu Leu Lys Glu Lys Met Asp Glu Leu Leu Pro Leu 
            100                 105                 110         


Ile Pro Val Leu Glu Gln Tyr Lys Thr Asp Ala Lys Leu Ile Thr Gln 
        115                 120                 125             


Phe Lys Glu Glu Ile Arg Asn Leu Ser Ala Val Leu Thr Gly Ile Gln 
    130                 135                 140                 


Glu Glu Ile Gly Ala Tyr Asp Tyr Glu Glu Leu His Gln Arg Val Leu 
145                 150                 155                 160 


Ser Leu Glu Thr Arg Leu Arg Asp Cys Met Lys Lys Leu Thr Cys Gly 
                165                 170                 175     


Lys Leu Met Lys Ile Thr Gly Pro Val Thr Val Lys Thr Ser Gly Thr 
            180                 185                 190         


Arg Phe Gly Ala Trp Met Thr Asp Pro Leu Ala Ser Glu Lys Asn Asn 
        195                 200                 205             


Arg Val Trp Tyr Met Asp Ser Tyr Thr Asn Asn Lys Ile Val Arg Glu 
    210                 215                 220                 


Tyr Lys Ser Ile Ala Asp Phe Val Ser Gly Ala Glu Ser Arg Thr Tyr 
225                 230                 235                 240 


Asn Leu Pro Phe Lys Trp Ala Gly Thr Asn His Val Val Tyr Asn Gly 
                245                 250                 255     


Ser Leu Tyr Phe Asn Lys Tyr Gln Ser Asn Ile Ile Ile Lys Tyr Ser 
            260                 265                 270         


Phe Asp Met Gly Arg Val Leu Ala Gln Arg Ser Leu Glu Tyr Ala Gly 
        275                 280                 285             


Phe His Asn Val Tyr Pro Tyr Thr Trp Gly Gly Phe Ser Asp Ile Asp 
    290                 295                 300                 


Leu Met Ala Asp Glu Ile Gly Leu Trp Ala Val Tyr Ala Thr Asn Gln 
305                 310                 315                 320 


Asn Ala Gly Asn Ile Val Ile Ser Gln Leu Asn Gln Asp Thr Leu Glu 
                325                 330                 335     


Val Met Lys Ser Trp Ser Thr Gly Tyr Pro Lys Arg Ser Ala Gly Glu 
            340                 345                 350         


Ser Phe Met Ile Cys Gly Thr Leu Tyr Val Thr Asn Ser His Leu Thr 
        355                 360                 365             


Gly Ala Lys Val Tyr Tyr Ser Tyr Ser Thr Lys Thr Ser Thr Tyr Glu 
    370                 375                 380                 


Tyr Thr Asp Ile Pro Phe His Asn Gln Tyr Phe His Ile Ser Met Leu 
385                 390                 395                 400 


Asp Tyr Asn Ala Arg Asp Arg Ala Leu Cys Ala Trp Asn Asn Gly His 
                405                 410                 415     


Gln Val Leu Phe Asn Val Thr Leu Phe His Ile Ile Lys Thr Glu Asp 
            420                 425                 430         


Asp Thr 
        


<210>  2810
<211>  586
<212>  PRT
<213>  Homo Sapiens

<400>  2810

Leu Glu Ser Thr Lys Leu Leu Ala Asp Leu Lys Lys Cys Gly Asp Leu 
1               5                   10                  15      


Glu Cys Glu Ala Leu Ile Asn Arg Val Ser Ala Met Arg Asp Tyr Arg 
            20                  25                  30          


Gly Pro Asp Cys Arg Tyr Leu Asn Phe Thr Lys Gly Glu Glu Ile Ser 
        35                  40                  45              


Val Tyr Val Lys Leu Ala Gly Glu Arg Glu Asp Leu Trp Ala Gly Ser 
    50                  55                  60                  


Lys Gly Lys Glu Phe Gly Tyr Phe Pro Arg Asp Ala Val Gln Ile Glu 
65                  70                  75                  80  


Glu Val Phe Ile Ser Glu Glu Ile Gln Met Ser Thr Lys Glu Ser Asp 
                85                  90                  95      


Phe Leu Cys Leu Leu Gly Val Ser Tyr Thr Phe Asp Asn Glu Asp Ser 
            100                 105                 110         


Glu Leu Asn Gly Asp Tyr Gly Glu Asn Ile Tyr Pro Tyr Glu Glu Asp 
        115                 120                 125             


Lys Asp Glu Lys Ser Ser Ile Tyr Glu Ser Asp Phe Gln Ile Glu Pro 
    130                 135                 140                 


Gly Phe Tyr Ala Thr Tyr Glu Ser Thr Leu Phe Glu Asp Gln Val Pro 
145                 150                 155                 160 


Ala Leu Glu Ala Pro Glu Asp Ile Gly Ser Thr Ser Glu Ser Lys Asp 
                165                 170                 175     


Trp Glu Glu Val Val Val Glu Ser Met Glu Gln Asp Arg Ile Pro Glu 
            180                 185                 190         


Val His Val Pro Pro Ser Ser Ala Val Ser Gly Val Lys Glu Trp Phe 
        195                 200                 205             


Gly Leu Gly Gly Glu Gln Ala Glu Glu Lys Ala Phe Glu Ser Val Ile 
    210                 215                 220                 


Glu Pro Val Gln Glu Ser Ser Phe Arg Ser Arg Lys Ile Ala Val Glu 
225                 230                 235                 240 


Asp Glu Asn Asp Leu Glu Glu Leu Asn Asn Gly Glu Pro Gln Thr Glu 
                245                 250                 255     


His Gln Gln Glu Ser Glu Ser Glu Ile Asp Ser Val Pro Lys Thr Gln 
            260                 265                 270         


Ser Glu Leu Ala Ser Glu Ser Glu His Ile Pro Lys Pro Gln Ser Thr 
        275                 280                 285             


Gly Trp Phe Gly Gly Gly Phe Thr Ser Tyr Leu Gly Phe Gly Asp Glu 
    290                 295                 300                 


Asp Thr Gly Leu Glu Leu Ile Ala Glu Glu Ser Asn Pro Pro Leu Gln 
305                 310                 315                 320 


Asp Phe Pro Asn Ser Ile Ser Ser Asp Lys Glu Ala Thr Val Pro Cys 
                325                 330                 335     


Thr Glu Ile Leu Thr Glu Lys Lys Asp Thr Ile Thr Asn Asp Ser Leu 
            340                 345                 350         


Ser Leu Lys Pro Ser Trp Phe Asp Phe Gly Phe Ala Ile Leu Gly Phe 
        355                 360                 365             


Ala Tyr Ala Lys Glu Asp Lys Ile Met Leu Asp Asp Arg Lys Asn Glu 
    370                 375                 380                 


Glu Asp Gly Gly Ala Asp Glu His Glu His Pro Leu Thr Ser Glu Leu 
385                 390                 395                 400 


Asp Pro Glu Lys Glu Gln Glu Ile Glu Thr Ile Lys Ile Ile Glu Thr 
                405                 410                 415     


Glu Asp Gln Ile Asp Lys Lys Pro Val Ser Glu Lys Thr Asp Glu Ser 
            420                 425                 430         


Asp Thr Ile Pro Tyr Leu Lys Lys Phe Leu Tyr Asn Phe Asp Asn Pro 
        435                 440                 445             


Trp Asn Phe Gln Asn Ile Pro Lys Glu Thr Glu Leu Pro Phe Pro Lys 
    450                 455                 460                 


Gln Ile Leu Asp Gln Asn Asn Val Ile Glu Asn Glu Glu Thr Gly Glu 
465                 470                 475                 480 


Phe Ser Ile Asp Asn Tyr Pro Thr Asp Asn Thr Lys Val Met Ile Phe 
                485                 490                 495     


Lys Ser Ser Tyr Ser Leu Ser Asp Met Val Ser Asn Ile Glu Leu Pro 
            500                 505                 510         


Thr Arg Ile His Glu Glu Val Tyr Phe Glu Pro Ser Ser Ser Lys Asp 
        515                 520                 525             


Ser Asp Glu Asn Ser Lys Pro Ser Val Asp Thr Glu Gly Pro Ala Leu 
    530                 535                 540                 


Val Glu Ile Asp Arg Ser Val Glu Asn Thr Leu Leu Asn Ser Gln Met 
545                 550                 555                 560 


Val Ser Thr Asp Asn Ser Leu Ser Ser Gln Asn Tyr Ile Ser Gln Lys 
                565                 570                 575     


Glu Asp Ala Ser Glu Phe Gln Ile Leu Lys 
            580                 585     


<210>  2811
<211>  462
<212>  PRT
<213>  Homo Sapiens

<400>  2811

Gln Gln Gly Asp Gly Cys Gly His Thr Val Leu Gly Pro Glu Ser Gly 
1               5                   10                  15      


Thr Leu Thr Ser Ile Asn Tyr Pro Gln Thr Tyr Pro Asn Ser Thr Val 
            20                  25                  30          


Cys Glu Trp Glu Ile Arg Val Lys Met Gly Glu Arg Val Arg Ile Lys 
        35                  40                  45              


Phe Gly Asp Phe Asp Ile Glu Asp Ser Asp Ser Cys His Phe Asn Tyr 
    50                  55                  60                  


Leu Arg Ile Tyr Asn Gly Ile Gly Val Ser Arg Thr Glu Ile Gly Lys 
65                  70                  75                  80  


Tyr Cys Gly Leu Gly Leu Gln Met Asn His Ser Ile Glu Ser Lys Gly 
                85                  90                  95      


Asn Glu Ile Thr Leu Leu Phe Met Ser Gly Ile His Val Ser Gly Arg 
            100                 105                 110         


Gly Phe Leu Ala Ser Tyr Ser Val Ile Asp Lys Gln Asp Leu Ile Thr 
        115                 120                 125             


Cys Leu Asp Thr Ala Ser Asn Phe Leu Glu Pro Glu Phe Ser Lys Tyr 
    130                 135                 140                 


Cys Pro Ala Gly Cys Leu Leu Pro Phe Ala Glu Ile Ser Gly Thr Ile 
145                 150                 155                 160 


Pro His Gly Tyr Arg Asp Ser Ser Pro Leu Cys Met Ala Gly Val His 
                165                 170                 175     


Ala Gly Val Val Ser Asn Thr Leu Gly Gly Gln Ile Ser Val Val Ile 
            180                 185                 190         


Ser Lys Gly Ile Pro Tyr Tyr Glu Ser Ser Leu Ala Asn Asn Val Thr 
        195                 200                 205             


Ser Val Val Gly His Leu Ser Thr Ser Leu Phe Thr Phe Lys Thr Ser 
    210                 215                 220                 


Gly Cys Tyr Gly Thr Leu Gly Met Glu Ser Gly Val Ile Ala Asp Pro 
225                 230                 235                 240 


Gln Ile Thr Ala Ser Ser Val Leu Glu Trp Thr Asp His Thr Gly Gln 
                245                 250                 255     


Glu Asn Ser Trp Lys Pro Lys Lys Ala Arg Leu Lys Lys Pro Gly Pro 
            260                 265                 270         


Pro Trp Ala Ala Phe Ala Thr Asp Glu Tyr Gln Trp Leu Gln Ile Asp 
        275                 280                 285             


Leu Asn Lys Glu Lys Lys Ile Thr Gly Ile Ile Thr Thr Gly Ser Thr 
    290                 295                 300                 


Met Val Glu His Asn Tyr Tyr Val Ser Ala Tyr Arg Ile Leu Tyr Ser 
305                 310                 315                 320 


Asp Asp Gly Gln Lys Trp Thr Val Tyr Arg Glu Pro Gly Val Glu Gln 
                325                 330                 335     


Asp Lys Ile Phe Gln Gly Asn Lys Asp Tyr His Gln Asp Val Arg Asn 
            340                 345                 350         


Asn Phe Leu Pro Pro Ile Ile Ala Arg Phe Ile Arg Val Asn Pro Thr 
        355                 360                 365             


Gln Trp Gln Gln Lys Ile Ala Met Lys Met Glu Leu Leu Gly Cys Gln 
    370                 375                 380                 


Phe Ile Pro Lys Gly Arg Pro Pro Lys Leu Thr Gln Pro Pro Pro Pro 
385                 390                 395                 400 


Arg Asn Ser Asn Asp Leu Lys Asn Thr Thr Ala Pro Pro Lys Ile Ala 
                405                 410                 415     


Lys Gly Arg Ala Pro Lys Phe Thr Gln Pro Leu Gln Pro Arg Ser Ser 
            420                 425                 430         


Asn Glu Phe Pro Ala Gln Thr Glu Gln Thr Thr Ala Ser Pro Asp Ile 
        435                 440                 445             


Arg Asn Thr Thr Val Thr Pro Asn Val Thr Lys Asp Val Ala 
    450                 455                 460         


<210>  2812
<211>  161
<212>  PRT
<213>  Homo Sapiens

<400>  2812

Tyr Arg His Gln Lys Arg Lys His Thr Cys Pro Ser Cys Gln His Ser 
1               5                   10                  15      


Trp Ile Glu Gly Val Gln Asp Asn Met Lys Leu His Lys Val Asp Phe 
            20                  25                  30          


Ile Trp Ile Asn Arg Asp Gln Arg Ser Phe Glu Trp Phe Val Ser Leu 
        35                  40                  45              


Leu Thr Lys Leu Glu Met Asp Gln Ala Glu Glu Ala Gln Tyr Gly Arg 
    50                  55                  60                  


Phe Leu Glu Leu His Met Tyr Met Thr Ser Ala Leu Gly Lys Asn Asp 
65                  70                  75                  80  


Met Lys Ala Ile Gly Leu Gln Met Ala Leu Asp Leu Leu Ala Asn Lys 
                85                  90                  95      


Glu Lys Lys Asp Ser Ile Thr Gly Leu Gln Thr Arg Thr Gln Pro Gly 
            100                 105                 110         


Arg Pro Asp Trp Ser Lys Val Phe Gln Lys Val Ala Ala Glu Lys Lys 
        115                 120                 125             


Gly Lys Val Gln Val Phe Phe Cys Gly Ser Pro Ala Leu Ala Lys Val 
    130                 135                 140                 


Leu Lys Gly His Cys Glu Lys Phe Gly Phe Arg Phe Phe Gln Glu Asn 
145                 150                 155                 160 


Phe 
    


<210>  2813
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  2813

Phe Leu Ile Asn Lys Val Pro Leu Pro Val Asp Lys Leu Ala Pro Leu 
1               5                   10                  15      


Pro Leu Asp Asn Ile Leu Pro Phe Met Asp Pro Leu Lys Leu Leu Leu 
            20                  25                  30          


Lys Thr Leu Gly Ile Ser Val Glu His Leu Val Glu Gly Leu Arg Lys 
        35                  40                  45              


Cys Val Asn Glu Leu Gly Pro Glu Ala Ser Glu Ala Val Lys Lys Leu 
    50                  55                  60                  


Leu Glu Ala Leu Ser His Leu Val 
65                  70          


<210>  2814
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  2814

Lys Ser Cys Ala Pro Asn Lys Ala Asp Val Ile Leu Val Phe Cys Tyr 
1               5                   10                  15      


Pro Lys Thr Ile Ile Thr Lys Ile Pro Glu Cys Pro Tyr Gly Trp Glu 
            20                  25                  30          


Val His Gln Leu Ala Leu Gly Gly Leu Cys Tyr Asn Gly Val His Glu 
        35                  40                  45              


Gly Gly Tyr Tyr Gln Phe Val Ile Pro Asp Leu Ser Pro Lys Asn Lys 
    50                  55                  60                  


Ser Tyr Cys Gly Thr Gln Ser Glu Tyr Lys Pro Pro Ile Tyr His Phe 
65                  70                  75                  80  


Tyr Ser His Ile Val Ser Asn Asp Thr Thr Val Ile Val Lys Asn Gln 
                85                  90                  95      


Pro Val Asn Tyr Ser Phe Ser Cys Thr Tyr His Ser Thr Tyr Leu Val 
            100                 105                 110         


Asn Gln Ala Ala Phe Asp Gln Arg Val Ala Thr Val His Val Lys Asn 
        115                 120                 125             


Gly Ser Met Gly Thr Phe Glu Ser Gln Leu Ser Leu Asn Phe Tyr Thr 
    130                 135                 140                 


Asn Ala Lys Phe Ser Ile Lys Lys Glu Ala Pro Phe Val Leu Glu Ala 
145                 150                 155                 160 


Ser Glu Ile Gly Ser Asp Leu Phe Ala Gly Val Glu Ala Lys Gly Leu 
                165                 170                 175     


Ser Ile Arg Phe Lys Val Val Leu Asn Ser Cys Trp Ala Thr Pro Ser 
            180                 185                 190         


Ala Asp Phe Met Tyr Pro Leu Gln Trp Gln Leu Ile Asn Lys Gly Cys 
        195                 200                 205             


Pro Thr Asp Glu Thr Val Leu Val His Glu Asn Gly Arg Asp His Arg 
    210                 215                 220                 


Ala Thr Phe Gln Phe Asn Ala Phe Arg Phe Gln Asn Ile Pro Lys Leu 
225                 230                 235                 240 


Ser Lys Val Trp Leu His Cys Glu Thr Phe Ile Cys Asp Ser Glu Lys 
                245                 250                 255     


Leu Ser Cys Pro Val Thr Cys Asp Lys Arg Lys Arg Leu Leu Arg Asp 
            260                 265                 270         


Gln Thr Gly Gly Val Leu Val Val Glu Leu Ser Leu Arg Ser Arg Gly 
        275                 280                 285             


<210>  2815
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  2815

Cys Gly Ile Pro Leu Asn Pro Ala Arg Asp Leu Gly Pro Arg Leu Phe 
1               5                   10                  15      


Thr Tyr Val Ala Gly Trp Gly Pro Glu Val Phe Ser Ala Gly Asn Gly 
            20                  25                  30          


Trp Trp Trp Val Pro Val Val Ala Pro Leu Val Gly Ala Thr Val Gly 
        35                  40                  45              


Thr Ala Thr Tyr Gln Leu Leu Val Ala Leu His His Pro Glu Gly Pro 
    50                  55                  60                  


Glu Pro Ala Gln Asp Leu Val Ser Ala Gln His Lys Ala Ser Glu Leu 
65                  70                  75                  80  


Glu Thr Pro Ala Ser Ala Gln Met Leu Glu Cys Lys Leu 
                85                  90              


<210>  2816
<211>  829
<212>  PRT
<213>  Homo Sapiens

<400>  2816

Ile Thr Cys Gly His Pro Gly Asn Pro Ala His Gly Phe Thr Asn Gly 
1               5                   10                  15      


Ser Glu Phe Asn Leu Asn Asp Val Val Asn Phe Thr Cys Asn Thr Gly 
            20                  25                  30          


Tyr Leu Leu Gln Gly Val Ser Arg Ala Gln Cys Arg Ser Asn Gly Gln 
        35                  40                  45              


Trp Ser Ser Pro Leu Pro Thr Cys Arg Val Val Asn Cys Ser Asp Pro 
    50                  55                  60                  


Gly Phe Val Glu Asn Ala Ile Arg His Gly Gln Gln Asn Phe Pro Glu 
65                  70                  75                  80  


Ser Phe Glu Tyr Gly Met Ser Ile Leu Tyr His Cys Lys Lys Gly Phe 
                85                  90                  95      


Tyr Leu Leu Gly Ser Ser Ala Leu Thr Cys Met Ala Asn Gly Leu Trp 
            100                 105                 110         


Asp Arg Ser Leu Pro Lys Cys Leu Ala Ile Ser Cys Gly His Pro Gly 
        115                 120                 125             


Val Pro Ala Asn Ala Val Leu Thr Gly Glu Leu Phe Thr Tyr Gly Ala 
    130                 135                 140                 


Val Val His Tyr Ser Cys Arg Gly Ser Glu Ser Leu Ile Gly Asn Asp 
145                 150                 155                 160 


Thr Arg Val Cys Gln Glu Asp Ser His Trp Ser Gly Ala Leu Pro His 
                165                 170                 175     


Cys Thr Gly Asn Asn Pro Gly Phe Cys Gly Asp Pro Gly Thr Pro Ala 
            180                 185                 190         


His Gly Ser Arg Leu Gly Asp Asp Phe Lys Thr Lys Ser Leu Leu Arg 
        195                 200                 205             


Phe Ser Cys Glu Met Gly His Gln Leu Arg Gly Ser Pro Glu Arg Thr 
    210                 215                 220                 


Cys Leu Leu Asn Gly Ser Trp Ser Gly Leu Gln Pro Val Cys Glu Ala 
225                 230                 235                 240 


Val Ser Cys Gly Asn Pro Gly Thr Pro Thr Asn Gly Met Ile Val Ser 
                245                 250                 255     


Ser Asp Gly Ile Leu Phe Ser Ser Ser Val Ile Tyr Ala Cys Trp Glu 
            260                 265                 270         


Gly Tyr Lys Thr Ser Gly Leu Met Thr Arg His Cys Thr Ala Asn Gly 
        275                 280                 285             


Thr Trp Thr Gly Thr Ala Pro Asp Cys Thr Ile Ile Ser Cys Gly Asp 
    290                 295                 300                 


Pro Gly Thr Leu Ala Asn Gly Ile Gln Phe Gly Thr Asp Phe Thr Phe 
305                 310                 315                 320 


Asn Lys Thr Val Ser Tyr Gln Cys Asn Pro Gly Tyr Val Met Glu Ala 
                325                 330                 335     


Val Thr Ser Ala Thr Ile Arg Cys Thr Lys Asp Gly Arg Trp Asn Pro 
            340                 345                 350         


Ser Lys Pro Val Cys Lys Ala Val Leu Cys Pro Gln Pro Pro Pro Val 
        355                 360                 365             


Gln Asn Gly Thr Val Glu Gly Ser Asp Phe Arg Trp Gly Ser Ser Ile 
    370                 375                 380                 


Ser Tyr Ser Cys Met Asp Gly Tyr Gln Leu Ser His Ser Ala Ile Leu 
385                 390                 395                 400 


Ser Cys Glu Gly Arg Gly Val Trp Lys Gly Glu Ile Pro Gln Cys Leu 
                405                 410                 415     


Pro Val Phe Cys Gly Asp Pro Gly Ile Pro Ala Glu Gly Arg Leu Ser 
            420                 425                 430         


Gly Lys Ser Phe Thr Tyr Lys Ser Glu Val Phe Phe Gln Cys Lys Ser 
        435                 440                 445             


Pro Phe Ile Leu Val Gly Ser Ser Arg Arg Val Cys Gln Ala Asp Gly 
    450                 455                 460                 


Thr Trp Ser Gly Ile Gln Pro Thr Cys Ile Asp Pro Ala His Asn Thr 
465                 470                 475                 480 


Cys Pro Asp Pro Gly Thr Pro His Phe Gly Ile Gln Asn Ser Ser Arg 
                485                 490                 495     


Gly Tyr Glu Val Gly Ser Thr Val Phe Phe Arg Cys Arg Lys Gly Tyr 
            500                 505                 510         


His Ile Gln Gly Ser Thr Thr Arg Thr Cys Leu Ala Asn Leu Thr Trp 
        515                 520                 525             


Ser Gly Ile Gln Thr Glu Cys Ile Pro His Ala Cys Arg Gln Pro Glu 
    530                 535                 540                 


Thr Pro Ala His Ala Asp Val Arg Ala Ile Asp Leu Pro Thr Phe Gly 
545                 550                 555                 560 


Tyr Thr Leu Val Tyr Thr Cys His Pro Gly Phe Phe Leu Ala Gly Gly 
                565                 570                 575     


Ser Glu His Arg Thr Cys Lys Ala Asp Met Lys Trp Thr Gly Lys Ser 
            580                 585                 590         


Pro Val Cys Lys Ser Lys Gly Val Arg Glu Val Asn Glu Thr Val Thr 
        595                 600                 605             


Lys Thr Pro Val Pro Ser Asp Val Phe Phe Val Asn Ser Leu Trp Lys 
    610                 615                 620                 


Gly Tyr Tyr Glu Tyr Leu Gly Lys Arg Gln Pro Ala Thr Leu Thr Val 
625                 630                 635                 640 


Asp Trp Phe Asn Ala Thr Ser Ser Lys Val Asn Ala Thr Phe Ser Glu 
                645                 650                 655     


Ala Ser Pro Val Glu Leu Lys Leu Thr Gly Ile Tyr Lys Lys Glu Glu 
            660                 665                 670         


Ala His Leu Leu Leu Lys Ala Phe Gln Ile Lys Gly Gln Ala Asp Ile 
        675                 680                 685             


Phe Val Ser Lys Phe Glu Asn Asp Asn Trp Gly Leu Asp Gly Tyr Val 
    690                 695                 700                 


Ser Ser Gly Leu Glu Arg Gly Gly Phe Thr Phe Gln Gly Asp Ile His 
705                 710                 715                 720 


Gly Lys Asp Phe Gly Lys Phe Lys Leu Glu Arg Gln Asp Pro Leu Asn 
                725                 730                 735     


Pro Asp Gln Asp Ser Ser Ser His Tyr His Gly Thr Ser Ser Gly Ser 
            740                 745                 750         


Val Ala Ala Ala Ile Leu Val Pro Phe Phe Ala Leu Ile Leu Ser Gly 
        755                 760                 765             


Phe Ala Phe Tyr Leu Tyr Lys His Arg Thr Arg Pro Lys Val Gln Tyr 
    770                 775                 780                 


Asn Gly Tyr Ala Gly His Glu Asn Ser Asn Gly Gln Ala Ser Phe Glu 
785                 790                 795                 800 


Asn Pro Met Tyr Asp Thr Asn Leu Lys Pro Thr Glu Ala Lys Ala Val 
                805                 810                 815     


Arg Phe Asp Thr Thr Leu Asn Thr Val Cys Thr Val Val 
            820                 825                 


<210>  2817
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  2817

Lys Lys Phe Gln Val Pro Cys Pro Val Glu Ala Ala Leu Ile Ile Asn 
1               5                   10                  15      


Glu Thr Ile Asn Thr Thr Leu Thr Gln Pro Thr Ala Leu Val Pro Ala 
            20                  25                  30          


Leu Ser His Asn Val Thr Glu Asn Asp Ser Cys Arg Pro His Tyr Phe 
        35                  40                  45              


Ile Phe Asn Ser Gln Thr 
    50                  


<210>  2818
<211>  94
<212>  PRT
<213>  Homo Sapiens

<400>  2818

Ser Ala Gln Val Ser Pro Arg Ile Thr Phe Lys Pro Ile Ala Pro Ser 
1               5                   10                  15      


Gly Gln Asn Ala Thr Cys Thr Arg Tyr Ser Tyr Cys Asn Glu Cys Met 
            20                  25                  30          


Leu Asp Pro Asp Cys Gly Phe Cys Tyr Lys Met Asn Lys Ser Thr Val 
        35                  40                  45              


Ile Asp Ser Ser Cys Val Pro Val Asn Lys Ala Ser Thr Asn Glu Ala 
    50                  55                  60                  


Ala Trp Gly Arg Cys Glu Asn Glu Thr Lys Phe Lys Thr Glu Asp Ile 
65                  70                  75                  80  


Phe Trp Ala Tyr Asn Phe Cys Pro Thr Pro Tyr Ser Trp Thr 
                85                  90                  


<210>  2819
<211>  84
<212>  PRT
<213>  Homo Sapiens

<400>  2819

Phe Leu Val Gly Ser Ala Lys Pro Val Ala Gln Pro Val Ala Ala Leu 
1               5                   10                  15      


Glu Ser Ala Ala Glu Ala Gly Ala Gly Thr Leu Ala Asn Pro Leu Gly 
            20                  25                  30          


Thr Leu Asn Pro Leu Lys Leu Leu Leu Ser Ser Leu Gly Ile Pro Val 
        35                  40                  45              


Asn His Leu Ile Glu Gly Ser Gln Lys Cys Val Ala Glu Leu Gly Pro 
    50                  55                  60                  


Gln Ala Val Gly Ala Val Lys Ala Leu Lys Ala Leu Leu Gly Ala Leu 
65                  70                  75                  80  


Thr Val Phe Gly 
                


<210>  2820
<211>  53
<212>  PRT
<213>  Homo Sapiens

<400>  2820

Gly Ser Pro Ile Ser Cys Phe Ser Pro Ser Asn Phe Ser Ile Arg Gln 
1               5                   10                  15      


Ala Ala Tyr Val Asp Ser Ser Cys Trp Asp Ser Leu Leu His His Lys 
            20                  25                  30          


Gln Asp Gly Pro Gly Gln Asp Lys Met Lys Ser Leu Trp Pro His Lys 
        35                  40                  45              


Ala Leu Pro Tyr Ser 
    50              


<210>  2821
<211>  546
<212>  PRT
<213>  Homo Sapiens

<400>  2821

Gln Asp Trp Lys Ala Glu Arg Ser Gln Asp Pro Phe Glu Lys Cys Met 
1               5                   10                  15      


Gln Asp Pro Asp Tyr Glu Gln Leu Leu Lys Val Val Thr Trp Gly Leu 
            20                  25                  30          


Asn Arg Thr Leu Lys Pro Gln Arg Val Ile Val Val Gly Ala Gly Val 
        35                  40                  45              


Ala Gly Leu Val Ala Ala Lys Val Leu Ser Asp Ala Gly His Lys Val 
    50                  55                  60                  


Thr Ile Leu Glu Ala Asp Asn Arg Ile Gly Gly Arg Ile Phe Thr Tyr 
65                  70                  75                  80  


Arg Asp Gln Asn Met Gly Trp Ile Gly Glu Leu Gly Ala Met Arg Met 
                85                  90                  95      


Pro Ser Ser His Arg Ile Leu His Lys Leu Cys Gln Gly Leu Gly Leu 
            100                 105                 110         


Asn Leu Thr Lys Phe Thr Gln Tyr Asp Lys Asn Thr Trp Thr Glu Val 
        115                 120                 125             


His Glu Val Lys Leu Arg Asn Tyr Val Val Glu Lys Val Pro Glu Lys 
    130                 135                 140                 


Leu Gly Tyr Ala Leu Arg Pro Gln Glu Lys Gly His Ser Pro Glu Asp 
145                 150                 155                 160 


Ile Tyr Gln Met Ala Leu Asn Gln Ala Leu Lys Asp Leu Lys Ala Leu 
                165                 170                 175     


Gly Cys Arg Lys Ala Met Lys Lys Phe Glu Arg His Thr Leu Leu Glu 
            180                 185                 190         


Tyr Leu Leu Gly Glu Gly Asn Leu Ser Arg Pro Ala Val Gln Leu Leu 
        195                 200                 205             


Gly Asp Val Met Ser Glu Asp Gly Phe Phe Tyr Leu Ser Phe Ala Glu 
    210                 215                 220                 


Ala Leu Arg Ala His Ser Cys Leu Ser Asp Arg Leu Gln Tyr Ser Arg 
225                 230                 235                 240 


Ile Val Gly Gly Trp Asp Leu Leu Pro Arg Ala Leu Leu Ser Ser Leu 
                245                 250                 255     


Ser Gly Leu Val Leu Leu Asn Ala Pro Val Val Ala Met Thr Gln Gly 
            260                 265                 270         


Pro His Asp Val His Val Gln Ile Glu Thr Ser Pro Pro Ala Arg Asn 
        275                 280                 285             


Leu Lys Val Leu Lys Ala Asp Val Val Leu Leu Thr Ala Ser Gly Pro 
    290                 295                 300                 


Ala Val Lys Arg Ile Thr Phe Ser Pro Pro Leu Pro Arg His Met Gln 
305                 310                 315                 320 


Glu Ala Leu Arg Arg Leu His Tyr Val Pro Ala Thr Lys Val Phe Leu 
                325                 330                 335     


Ser Phe Arg Arg Pro Phe Trp Arg Glu Glu His Ile Glu Gly Gly His 
            340                 345                 350         


Ser Asn Thr Asp Arg Pro Ser Arg Met Ile Phe Tyr Pro Pro Pro Arg 
        355                 360                 365             


Glu Gly Ala Leu Leu Leu Ala Ser Tyr Thr Trp Ser Asp Ala Ala Ala 
    370                 375                 380                 


Ala Phe Ala Gly Leu Ser Arg Glu Glu Ala Leu Arg Leu Ala Leu Asp 
385                 390                 395                 400 


Asp Val Ala Ala Leu His Gly Pro Val Val Arg Gln Leu Trp Asp Gly 
                405                 410                 415     


Thr Gly Val Val Lys Arg Trp Ala Glu Asp Gln His Ser Gln Gly Gly 
            420                 425                 430         


Phe Val Val Gln Pro Pro Ala Leu Trp Gln Thr Glu Lys Asp Asp Trp 
        435                 440                 445             


Thr Val Pro Tyr Gly Arg Ile Tyr Phe Ala Gly Glu His Thr Ala Tyr 
    450                 455                 460                 


Pro His Gly Trp Val Glu Thr Ala Val Lys Ser Ala Leu Arg Ala Ala 
465                 470                 475                 480 


Ile Lys Ile Asn Ser Arg Lys Gly Pro Ala Ser Asp Thr Ala Ser Pro 
                485                 490                 495     


Glu Gly His Ala Ser Asp Met Glu Gly Gln Gly His Val His Gly Val 
            500                 505                 510         


Ala Ser Ser Pro Ser His Asp Leu Ala Lys Glu Glu Gly Ser His Pro 
        515                 520                 525             


Pro Val Gln Gly Gln Leu Ser Leu Gln Asn Thr Thr His Thr Arg Thr 
    530                 535                 540                 


Ser His 
545     


<210>  2822
<211>  110
<212>  PRT
<213>  Homo Sapiens

<400>  2822

His His Leu Pro Asp Arg Ser Gln Leu Cys Arg Lys Val Lys Phe Gln 
1               5                   10                  15      


Val Asp Phe Asn Leu Ile Gly Trp Gly Ser Trp Ile Ile Tyr Pro Lys 
            20                  25                  30          


Gln Tyr Asn Ala Tyr Arg Cys Glu Gly Glu Cys Pro Asn Pro Val Gly 
        35                  40                  45              


Glu Glu Phe His Pro Thr Asn His Ala Tyr Ile Gln Ser Leu Leu Lys 
    50                  55                  60                  


Arg Tyr Gln Pro His Arg Val Pro Ser Thr Cys Cys Ala Pro Val Lys 
65                  70                  75                  80  


Thr Lys Pro Leu Ser Met Leu Tyr Val Asp Asn Gly Arg Val Leu Leu 
                85                  90                  95      


Asp His His Lys Asp Met Ile Val Glu Glu Cys Gly Cys Leu 
            100                 105                 110 


<210>  2823
<211>  116
<212>  PRT
<213>  Homo Sapiens

<400>  2823

His Asp Asp Asp Trp Ile Asp Pro Thr Asp Met Leu Asn Tyr Asp Ala 
1               5                   10                  15      


Ala Ser Gly Thr Met Arg Lys Ser Gln Ala Lys Tyr Gly Ile Ser Gly 
            20                  25                  30          


Glu Lys Asp Val Ser Pro Asp Leu Ser Cys Ala Asp Glu Ile Ser Glu 
        35                  40                  45              


Cys Tyr His Lys Leu Asp Ser Leu Thr Tyr Lys Ile Asp Glu Cys Glu 
    50                  55                  60                  


Lys Lys Lys Arg Glu Asp Tyr Glu Ser Gln Ser Asn Pro Val Phe Arg 
65                  70                  75                  80  


Arg Tyr Leu Asn Lys Ile Leu Ile Glu Ala Gly Lys Leu Gly Leu Phe 
                85                  90                  95      


His Asp Phe Glu Thr Trp Lys Trp Arg Phe Glu Asp Ser Phe Gly Val 
            100                 105                 110         


Asp Pro Tyr Asn 
        115     


<210>  2824
<211>  168
<212>  PRT
<213>  Homo Sapiens

<400>  2824

Gln Gln Glu Gln Asp Phe Tyr Asp Phe Lys Ala Val Asn Ile Arg Gly 
1               5                   10                  15      


Lys Leu Val Ser Leu Glu Lys Tyr Arg Gly Ser Val Ser Leu Val Val 
            20                  25                  30          


Asn Val Ala Ser Glu Cys Gly Phe Thr Asp Gln His Tyr Arg Ala Leu 
        35                  40                  45              


Gln Gln Leu Gln Arg Asp Leu Gly Pro His His Phe Asn Val Leu Ala 
    50                  55                  60                  


Phe Pro Cys Asn Gln Phe Gly Gln Gln Glu Pro Asp Ser Asn Lys Glu 
65                  70                  75                  80  


Ile Glu Ser Phe Ala Arg Arg Thr Tyr Ser Val Ser Phe Pro Met Phe 
                85                  90                  95      


Ser Lys Ile Ala Val Thr Gly Thr Gly Ala His Pro Ala Phe Lys Tyr 
            100                 105                 110         


Leu Ala Gln Thr Ser Gly Lys Glu Pro Thr Trp Asn Phe Trp Lys Tyr 
        115                 120                 125             


Leu Val Ala Pro Asp Gly Lys Val Val Gly Ala Trp Asp Pro Thr Val 
    130                 135                 140                 


Ser Val Glu Glu Val Arg Pro Gln Ile Thr Ala Leu Val Arg Lys Leu 
145                 150                 155                 160 


Ile Leu Leu Lys Arg Glu Asp Leu 
                165             


<210>  2825
<211>  106
<212>  PRT
<213>  Homo Sapiens

<400>  2825

Gln Glu Ala Val Ile Pro Gly Cys His Leu His Pro Phe Asn Val Thr 
1               5                   10                  15      


Val Arg Ser Asp Arg Gln Gly Thr Cys Gln Gly Ser His Val Ala Gln 
            20                  25                  30          


Ala Cys Val Gly His Cys Glu Ser Ser Ala Phe Pro Ser Arg Tyr Ser 
        35                  40                  45              


Val Leu Val Ala Ser Gly Tyr Arg His Asn Ile Thr Ser Val Ser Gln 
    50                  55                  60                  


Cys Cys Thr Ile Ser Gly Leu Lys Lys Val Lys Val Gln Leu Gln Cys 
65                  70                  75                  80  


Val Gly Ser Arg Arg Glu Glu Leu Glu Ile Phe Thr Ala Arg Ala Cys 
                85                  90                  95      


Gln Cys Asp Met Cys Arg Leu Ser Arg Tyr 
            100                 105     


<210>  2826
<211>  175
<212>  PRT
<213>  Homo Sapiens

<400>  2826

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Ile Arg Pro Pro 
            20                  25                  30          


Tyr Pro Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His Gln 
        35                  40                  45              


Ile Ile Pro Val Leu Ser Gln Gln His Pro Pro Thr His Thr Leu Gln 
    50                  55                  60                  


Pro His His His Ile Pro Val Val Pro Ala Gln Gln Pro Val Ile Pro 
65                  70                  75                  80  


Gln Gln Pro Met Met Pro Val Pro Gly Gln His Ser Met Thr Pro Ile 
                85                  90                  95      


Gln His His Gln Pro Asn Leu Pro Pro Pro Ala Gln Gln Pro Tyr Gln 
            100                 105                 110         


Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Met Gln Pro Gln Pro 
        115                 120                 125             


Pro Val His Pro Met Gln Pro Leu Pro Pro Gln Pro Pro Leu Pro Pro 
    130                 135                 140                 


Met Phe Pro Met Gln Pro Leu Pro Pro Met Leu Pro Asp Leu Thr Leu 
145                 150                 155                 160 


Glu Ala Trp Pro Ser Thr Asp Lys Thr Lys Arg Glu Glu Val Asp 
                165                 170                 175 


<210>  2827
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  2827

Met Pro Leu Pro Pro His Pro Gly His Pro Gly Tyr Ile Asn Phe Ser 
1               5                   10                  15      


Tyr Glu Val Leu Thr Pro Leu Lys Trp Tyr Gln Ser Met Ile Arg Pro 
            20                  25                  30          


Pro Tyr Ser Ser Tyr Gly Tyr Glu Pro Met Gly Gly Trp Leu His His 
        35                  40                  45              


Gln Ile Ile Pro Val Val Ser Gln Gln His Pro Leu Thr His Thr Leu 
    50                  55                  60                  


Gln Ser His His His Ile Pro Val Val Pro Ala Gln Gln Pro Arg Val 
65                  70                  75                  80  


Arg Gln Gln Ala Leu Met Pro Val Pro Gly Gln Gln Ser Met Thr Pro 
                85                  90                  95      


Thr Gln His His Gln Pro Asn Leu Pro Leu Pro Ala Gln Gln Pro Phe 
            100                 105                 110         


Gln Pro Gln Pro Val Gln Pro Gln Pro His Gln Pro Met Gln Pro Gln 
        115                 120                 125             


Pro Pro Val Gln Pro Met Gln Pro Leu Leu Pro Gln Pro Pro Leu Pro 
    130                 135                 140                 


Pro Met Phe Pro Leu Arg Pro Leu Pro Pro Ile Leu Pro Asp Leu His 
145                 150                 155                 160 


Leu Glu Ala Trp Pro Ala Thr Asp Lys Thr Lys Gln Glu Glu Val Asp 
                165                 170                 175     


<210>  2828
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  2828

Ser Ser Leu Gly Val Val Thr Cys Gly Ser Val Val Lys Leu Leu Asn 
1               5                   10                  15      


Thr Arg His Asn Val Arg Leu His Ser His Asp Val Arg Tyr Gly Ser 
            20                  25                  30          


Gly Ser Gly Gln Gln Ser Val Thr Gly Val Thr Ser Val Asp Asp Ser 
        35                  40                  45              


Asn Ser Tyr Trp Arg Ile Arg Gly Lys Ser Ala Thr Val Cys Glu Arg 
    50                  55                  60                  


Gly Thr Pro Ile Lys Cys Gly Gln Pro Ile Arg Leu Thr His Val Asn 
65                  70                  75                  80  


Thr Gly Arg Asn Leu His Ser His His Phe Thr Ser Pro Leu Ser Gly 
                85                  90                  95      


Asn Gln Glu Val Ser Ala Phe Gly Glu Glu Gly Glu Gly Asp Tyr Leu 
            100                 105                 110         


Asp Asp Trp Thr Val Leu Cys Asn Gly Pro Tyr Trp Val Arg Asp Gly 
        115                 120                 125             


Glu Val Arg Phe Lys His Ser Ser Thr Glu Val Leu Leu Ser Val Thr 
    130                 135                 140                 


Gly Glu Gln Tyr Gly Arg Pro Ile Ser Gly Gln Lys Glu Val His Gly 
145                 150                 155                 160 


Met Ala Gln Pro Ser Gln Asn Asn Tyr Trp Lys Ala Met Glu Gly Ile 
                165                 170                 175     


Phe Met Lys Pro Ser Glu Leu Leu Lys Ala Glu Ala His His Ala Glu 
            180                 185                 190         


Leu 
    


<210>  2829
<211>  368
<212>  PRT
<213>  Homo Sapiens

<400>  2829

Glu Asn Asp Phe Gly Leu Val Gln Pro Leu Val Thr Met Glu Gln Leu 
1               5                   10                  15      


Leu Trp Val Ser Gly Arg Gln Ile Gly Ser Val Asp Thr Phe Arg Ile 
            20                  25                  30          


Pro Leu Ile Thr Ala Thr Pro Arg Gly Thr Leu Leu Ala Phe Ala Glu 
        35                  40                  45              


Ala Arg Lys Met Ser Ser Ser Asp Glu Gly Ala Lys Phe Ile Ala Leu 
    50                  55                  60                  


Arg Arg Ser Met Asp Gln Gly Ser Thr Trp Ser Pro Thr Ala Phe Ile 
65                  70                  75                  80  


Val Asn Asp Gly Asp Val Pro Asp Gly Leu Asn Leu Gly Ala Val Val 
                85                  90                  95      


Ser Asp Val Glu Thr Gly Val Val Phe Leu Phe Tyr Ser Leu Cys Ala 
            100                 105                 110         


His Lys Ala Gly Cys Gln Val Ala Ser Thr Met Leu Val Trp Ser Lys 
        115                 120                 125             


Asp Asp Gly Val Ser Trp Ser Thr Pro Arg Asn Leu Ser Leu Asp Ile 
    130                 135                 140                 


Gly Thr Glu Val Phe Ala Pro Gly Pro Gly Ser Gly Ile Gln Lys Gln 
145                 150                 155                 160 


Arg Glu Pro Arg Lys Gly Arg Leu Ile Val Cys Gly His Gly Thr Leu 
                165                 170                 175     


Glu Arg Asp Gly Val Phe Cys Leu Leu Ser Asp Asp His Gly Ala Ser 
            180                 185                 190         


Trp Arg Tyr Gly Ser Gly Val Ser Gly Ile Pro Tyr Gly Gln Pro Lys 
        195                 200                 205             


Gln Glu Asn Asp Phe Asn Pro Asp Glu Cys Gln Pro Tyr Glu Leu Pro 
    210                 215                 220                 


Asp Gly Ser Val Val Ile Asn Ala Arg Asn Gln Asn Asn Tyr His Cys 
225                 230                 235                 240 


His Cys Arg Ile Val Leu Arg Ser Tyr Asp Ala Cys Asp Thr Leu Arg 
                245                 250                 255     


Pro Arg Asp Val Thr Phe Asp Pro Glu Leu Val Asp Pro Val Val Ala 
            260                 265                 270         


Ala Gly Ala Val Val Thr Ser Ser Gly Ile Val Phe Phe Ser Asn Pro 
        275                 280                 285             


Ala His Pro Glu Phe Arg Val Asn Leu Thr Leu Arg Trp Ser Phe Ser 
    290                 295                 300                 


Asn Gly Thr Ser Trp Arg Lys Glu Thr Val Gln Leu Trp Pro Gly Pro 
305                 310                 315                 320 


Ser Gly Tyr Ser Ser Leu Ala Thr Leu Glu Gly Ser Met Asp Gly Glu 
                325                 330                 335     


Glu Gln Ala Pro Gln Leu Tyr Val Leu Tyr Glu Lys Gly Arg Asn His 
            340                 345                 350         


Tyr Thr Glu Ser Ile Ser Val Ala Lys Ile Ser Val Tyr Gly Thr Leu 
        355                 360                 365             


<210>  2830
<211>  678
<212>  PRT
<213>  Homo Sapiens

<400>  2830

Ser Ala Pro Gly Glu Asp Glu Glu Cys Gly Arg Val Arg Asp Phe Val 
1               5                   10                  15      


Ala Lys Leu Ala Asn Asn Thr His Gln His Val Phe Asp Asp Leu Arg 
            20                  25                  30          


Gly Ser Val Ser Leu Ser Trp Val Gly Asp Ser Thr Gly Val Ile Leu 
        35                  40                  45              


Val Leu Thr Thr Phe His Val Pro Leu Val Ile Met Thr Phe Gly Gln 
    50                  55                  60                  


Ser Lys Leu Tyr Arg Ser Glu Asp Tyr Gly Lys Asn Phe Lys Asp Ile 
65                  70                  75                  80  


Thr Asp Leu Ile Asn Asn Thr Phe Ile Arg Thr Glu Phe Gly Met Ala 
                85                  90                  95      


Ile Gly Pro Glu Asn Ser Gly Lys Val Val Leu Thr Ala Glu Val Ser 
            100                 105                 110         


Gly Gly Ser Arg Gly Gly Arg Ile Phe Arg Ser Ser Asp Phe Ala Lys 
        115                 120                 125             


Asn Phe Val Gln Thr Asp Leu Pro Phe His Pro Leu Thr Gln Met Met 
    130                 135                 140                 


Tyr Ser Pro Gln Asn Ser Asp Tyr Leu Leu Ala Leu Ser Thr Glu Asn 
145                 150                 155                 160 


Gly Leu Trp Val Ser Lys Asn Phe Gly Gly Lys Trp Glu Glu Ile His 
                165                 170                 175     


Lys Ala Val Cys Leu Ala Lys Trp Gly Ser Asp Asn Thr Ile Phe Phe 
            180                 185                 190         


Thr Thr Tyr Ala Asn Gly Ser Cys Lys Ala Asp Leu Gly Ala Leu Glu 
        195                 200                 205             


Leu Trp Arg Thr Ser Asp Leu Gly Lys Ser Phe Lys Thr Ile Gly Val 
    210                 215                 220                 


Lys Ile Tyr Ser Phe Gly Leu Gly Gly Arg Phe Leu Phe Ala Ser Val 
225                 230                 235                 240 


Met Ala Asp Lys Asp Thr Thr Arg Arg Ile His Val Ser Thr Asp Gln 
                245                 250                 255     


Gly Asp Thr Trp Ser Met Ala Gln Leu Pro Ser Val Gly Gln Glu Gln 
            260                 265                 270         


Phe Tyr Ser Ile Leu Ala Ala Asn Asp Asp Met Val Phe Met His Val 
        275                 280                 285             


Asp Glu Pro Gly Asp Thr Gly Phe Gly Thr Ile Phe Thr Ser Asp Asp 
    290                 295                 300                 


Arg Gly Ile Val Tyr Ser Lys Ser Leu Asp Arg His Leu Tyr Thr Thr 
305                 310                 315                 320 


Thr Gly Gly Glu Thr Asp Phe Thr Asn Val Thr Ser Leu Arg Gly Val 
                325                 330                 335     


Tyr Ile Thr Ser Val Leu Ser Glu Asp Asn Ser Ile Gln Thr Met Ile 
            340                 345                 350         


Thr Phe Asp Gln Gly Gly Arg Trp Thr His Leu Arg Lys Pro Glu Asn 
        355                 360                 365             


Ser Glu Cys Asp Ala Thr Ala Lys Asn Lys Asn Glu Cys Ser Leu His 
    370                 375                 380                 


Ile His Ala Ser Tyr Ser Ile Ser Gln Lys Leu Asn Val Pro Met Ala 
385                 390                 395                 400 


Pro Leu Ser Glu Pro Asn Ala Val Gly Ile Val Ile Ala His Gly Ser 
                405                 410                 415     


Val Gly Asp Ala Ile Ser Val Met Val Pro Asp Val Tyr Ile Ser Asp 
            420                 425                 430         


Asp Gly Gly Tyr Ser Trp Thr Lys Met Leu Glu Gly Pro His Tyr Tyr 
        435                 440                 445             


Thr Ile Leu Asp Ser Gly Gly Ile Ile Val Ala Ile Glu His Ser Ser 
    450                 455                 460                 


Arg Pro Ile Asn Val Ile Lys Phe Ser Thr Asp Glu Gly Gln Cys Trp 
465                 470                 475                 480 


Gln Thr Tyr Thr Phe Thr Arg Asp Pro Ile Tyr Phe Thr Gly Leu Ala 
                485                 490                 495     


Ser Glu Pro Gly Ala Arg Ser Met Asn Ile Ser Ile Trp Gly Phe Thr 
            500                 505                 510         


Glu Ser Phe Leu Thr Ser Gln Trp Val Ser Tyr Thr Ile Asp Phe Lys 
        515                 520                 525             


Asp Ile Leu Glu Arg Asn Cys Glu Glu Lys Asp Tyr Thr Ile Trp Leu 
    530                 535                 540                 


Ala His Ser Thr Asp Pro Glu Asp Tyr Glu Asp Gly Cys Ile Leu Gly 
545                 550                 555                 560 


Tyr Lys Glu Gln Phe Leu Arg Leu Arg Lys Ser Ser Val Cys Gln Asn 
                565                 570                 575     


Gly Arg Asp Tyr Val Val Thr Lys Gln Pro Ser Ile Cys Leu Cys Ser 
            580                 585                 590         


Leu Glu Asp Phe Leu Cys Asp Phe Gly Tyr Tyr Arg Pro Glu Asn Asp 
        595                 600                 605             


Ser Lys Cys Val Glu Gln Pro Glu Leu Lys Gly His Asp Leu Glu Phe 
    610                 615                 620                 


Cys Leu Tyr Gly Arg Glu Glu His Leu Thr Thr Asn Gly Tyr Arg Lys 
625                 630                 635                 640 


Ile Pro Gly Asp Lys Cys Gln Gly Gly Val Asn Pro Val Arg Glu Val 
                645                 650                 655     


Lys Asp Leu Lys Lys Lys Cys Thr Ser Asn Phe Leu Ser Pro Glu Lys 
            660                 665                 670         


Gln Asn Ser Lys Ser Asn 
        675             


<210>  2831
<211>  306
<212>  PRT
<213>  Homo Sapiens

<400>  2831

Ile Pro Ile Asp Asp Pro Glu Asp Gly Gly Lys His Trp Val Val Ile 
1               5                   10                  15      


Val Ala Gly Ser Asn Gly Trp Tyr Asn Tyr Arg His Gln Ala Asp Ala 
            20                  25                  30          


Cys His Ala Tyr Gln Ile Ile His Arg Asn Gly Ile Pro Asp Glu Gln 
        35                  40                  45              


Ile Val Val Met Met Tyr Asp Asp Ile Ala Tyr Ser Glu Asp Asn Pro 
    50                  55                  60                  


Thr Pro Gly Ile Val Ile Asn Arg Pro Asn Gly Thr Asp Val Tyr Gln 
65                  70                  75                  80  


Gly Val Pro Lys Asp Tyr Thr Gly Glu Asp Val Thr Pro Gln Asn Phe 
                85                  90                  95      


Leu Ala Val Leu Arg Gly Asp Ala Glu Ala Val Lys Gly Ile Gly Ser 
            100                 105                 110         


Gly Lys Val Leu Lys Ser Gly Pro Gln Asp His Val Phe Ile Tyr Phe 
        115                 120                 125             


Thr Asp His Gly Ser Thr Gly Ile Leu Val Phe Pro Asn Glu Asp Leu 
    130                 135                 140                 


His Val Lys Asp Leu Asn Glu Thr Ile His Tyr Met Tyr Lys His Lys 
145                 150                 155                 160 


Met Tyr Arg Lys Met Val Phe Tyr Ile Glu Ala Cys Glu Ser Gly Ser 
                165                 170                 175     


Met Met Asn His Leu Pro Asp Asn Ile Asn Val Tyr Ala Thr Thr Ala 
            180                 185                 190         


Ala Asn Pro Arg Glu Ser Ser Tyr Ala Cys Tyr Tyr Asp Glu Lys Arg 
        195                 200                 205             


Ser Thr Tyr Leu Gly Asp Trp Tyr Ser Val Asn Trp Met Glu Asp Ser 
    210                 215                 220                 


Asp Val Glu Asp Leu Thr Lys Glu Thr Leu His Lys Gln Tyr His Leu 
225                 230                 235                 240 


Val Lys Ser His Thr Asn Thr Ser His Val Met Gln Tyr Gly Asn Lys 
                245                 250                 255     


Thr Ile Ser Thr Met Lys Val Met Gln Phe Gln Gly Met Lys Arg Lys 
            260                 265                 270         


Ala Ser Ser Pro Val Pro Leu Pro Pro Val Thr His Leu Asp Leu Thr 
        275                 280                 285             


Pro Ser Pro Asp Val Pro Leu Thr Ile Met Lys Arg Lys Leu Met Asn 
    290                 295                 300                 


Thr Asn 
305     


<210>  2832
<211>  411
<212>  PRT
<213>  Homo Sapiens

<400>  2832

Tyr Leu Leu Leu Gly Arg Trp Arg Lys Lys His Leu Thr Phe Arg Ile 
1               5                   10                  15      


Leu Asn Leu Pro Ser Thr Leu Pro Pro His Thr Ala Arg Ala Ala Leu 
            20                  25                  30          


Arg Gln Ala Phe Gln Asp Trp Ser Asn Val Ala Pro Leu Thr Phe Gln 
        35                  40                  45              


Glu Val Gln Ala Gly Ala Ala Asp Ile Arg Leu Ser Phe His Gly Arg 
    50                  55                  60                  


Gln Ser Ser Tyr Cys Ser Asn Thr Phe Asp Gly Pro Gly Arg Val Leu 
65                  70                  75                  80  


Ala His Ala Asp Ile Pro Glu Leu Gly Ser Val His Phe Asp Glu Asp 
                85                  90                  95      


Glu Phe Trp Thr Glu Gly Thr Tyr Arg Gly Val Asn Leu Arg Ile Ile 
            100                 105                 110         


Ala Ala His Glu Val Gly His Ala Leu Gly Leu Gly His Ser Arg Tyr 
        115                 120                 125             


Ser Gln Ala Leu Met Ala Pro Val Tyr Glu Gly Tyr Arg Pro His Phe 
    130                 135                 140                 


Lys Leu His Pro Asp Asp Val Ala Gly Ile Gln Ala Leu Tyr Gly Lys 
145                 150                 155                 160 


Lys Ser Pro Val Ile Arg Asp Glu Glu Glu Glu Glu Thr Glu Leu Pro 
                165                 170                 175     


Thr Val Pro Pro Val Pro Thr Glu Pro Ser Pro Met Pro Asp Pro Cys 
            180                 185                 190         


Ser Ser Glu Leu Asp Ala Met Met Leu Gly Pro Arg Gly Lys Thr Tyr 
        195                 200                 205             


Ala Phe Lys Gly Asp Tyr Val Trp Thr Val Ser Asp Ser Gly Pro Gly 
    210                 215                 220                 


Pro Leu Phe Arg Val Ser Ala Leu Trp Glu Gly Leu Pro Gly Asn Leu 
225                 230                 235                 240 


Asp Ala Ala Val Tyr Ser Pro Arg Thr Gln Trp Ile His Phe Phe Lys 
                245                 250                 255     


Gly Asp Lys Val Trp Arg Tyr Ile Asn Phe Lys Met Ser Pro Gly Phe 
            260                 265                 270         


Pro Lys Lys Leu Asn Arg Val Glu Pro Asn Leu Asp Ala Ala Leu Tyr 
        275                 280                 285             


Trp Pro Leu Asn Gln Lys Val Phe Leu Phe Lys Gly Ser Gly Tyr Trp 
    290                 295                 300                 


Gln Trp Asp Glu Leu Ala Arg Thr Asp Phe Ser Ser Tyr Pro Lys Pro 
305                 310                 315                 320 


Ile Lys Gly Leu Phe Thr Gly Val Pro Asn Gln Pro Ser Ala Ala Met 
                325                 330                 335     


Ser Trp Gln Asp Gly Arg Val Tyr Phe Phe Lys Gly Lys Val Tyr Trp 
            340                 345                 350         


Arg Leu Asn Gln Gln Leu Arg Val Glu Lys Gly Tyr Pro Arg Asn Ile 
        355                 360                 365             


Ser His Asn Trp Met His Cys Arg Pro Arg Thr Ile Asp Thr Thr Pro 
    370                 375                 380                 


Ser Gly Gly Asn Thr Thr Pro Ser Gly Thr Gly Ile Thr Leu Asp Thr 
385                 390                 395                 400 


Thr Leu Ser Ala Thr Glu Thr Thr Phe Glu Tyr 
                405                 410     


<210>  2833
<211>  284
<212>  PRT
<213>  Homo Sapiens

<400>  2833

Gln Glu Thr Asp Ser Val Val Ser Ser Val Thr Thr Lys Val Lys Gly 
1               5                   10                  15      


Val Ala Val Thr Asn Thr Ser Lys Leu Gly Phe Arg Ile Trp Asp Val 
            20                  25                  30          


Ala Asp Tyr Val Ile Pro Ala Gln Glu Glu Asn Ser Leu Phe Val Met 
        35                  40                  45              


Thr Asn Val Ile Leu Thr Met Asn Gln Thr Gln Gly Leu Cys Pro Glu 
    50                  55                  60                  


Ile Pro Asp Ala Thr Thr Val Cys Lys Ser Asp Ala Ser Cys Thr Ala 
65                  70                  75                  80  


Gly Ser Ala Gly Thr His Ser Asn Gly Val Ser Thr Gly Arg Cys Val 
                85                  90                  95      


Ala Phe Asn Gly Ser Val Lys Thr Cys Glu Val Ala Ala Trp Cys Pro 
            100                 105                 110         


Val Glu Asp Asp Thr His Val Pro Gln Pro Ala Phe Leu Lys Ala Ala 
        115                 120                 125             


Glu Asn Phe Thr Leu Leu Val Lys Asn Asn Ile Trp Tyr Pro Lys Phe 
    130                 135                 140                 


Asn Phe Ser Lys Arg Asn Ile Leu Pro Asn Ile Thr Thr Thr Tyr Leu 
145                 150                 155                 160 


Lys Ser Cys Ile Tyr Asp Ala Lys Thr Asp Pro Phe Cys Pro Ile Phe 
                165                 170                 175     


Arg Leu Gly Lys Ile Val Glu Asn Ala Gly His Gly Phe Gln Asp Met 
            180                 185                 190         


Ala Val Glu Gly Gly Ile Met Gly Ile Gln Val Asn Trp Asp Cys Asn 
        195                 200                 205             


Leu Asp Arg Ala Ala Ser Leu Cys Leu Pro Arg Tyr Ser Phe Arg Arg 
    210                 215                 220                 


Leu Asp Thr Arg Asp Val Glu His Asn Val Ser Pro Gly Tyr Asn Phe 
225                 230                 235                 240 


Arg Phe Ala Lys Tyr Tyr Arg Asp Leu Ala Gly Asn Glu Gln Arg Thr 
                245                 250                 255     


Leu Ile Lys Ala Tyr Gly Ile Arg Phe Asp Ile Ile Val Phe Gly Lys 
            260                 265                 270         


Ala Gly Lys Phe Asp Ile Ile Pro Thr Met Ile Asn 
        275                 280                 


<210>  2834
<211>  288
<212>  PRT
<213>  Homo Sapiens

<400>  2834

Ser Asp Lys Leu Tyr Gln Arg Lys Glu Pro Val Ile Ser Ser Val His 
1               5                   10                  15      


Thr Lys Val Lys Gly Ile Ala Glu Val Lys Glu Glu Ile Val Glu Asn 
            20                  25                  30          


Gly Val Lys Lys Leu Val His Ser Val Phe Asp Thr Ala Asp Tyr Thr 
        35                  40                  45              


Phe Pro Leu Gln Gly Asn Ser Phe Phe Val Met Thr Asn Phe Leu Lys 
    50                  55                  60                  


Thr Glu Gly Gln Glu Gln Arg Leu Cys Pro Glu Tyr Pro Thr Arg Arg 
65                  70                  75                  80  


Thr Leu Cys Ser Ser Asp Arg Gly Cys Lys Lys Gly Trp Met Asp Pro 
                85                  90                  95      


Gln Ser Lys Gly Ile Gln Thr Gly Arg Cys Val Val His Glu Gly Asn 
            100                 105                 110         


Gln Lys Thr Cys Glu Val Ser Ala Trp Cys Pro Ile Glu Ala Val Glu 
        115                 120                 125             


Glu Ala Pro Arg Pro Ala Leu Leu Asn Ser Ala Glu Asn Phe Thr Val 
    130                 135                 140                 


Leu Ile Lys Asn Asn Ile Asp Phe Pro Gly His Asn Tyr Thr Thr Arg 
145                 150                 155                 160 


Asn Ile Leu Pro Gly Leu Asn Ile Thr Cys Thr Phe His Lys Thr Gln 
                165                 170                 175     


Asn Pro Gln Cys Pro Ile Phe Arg Leu Gly Asp Ile Phe Arg Glu Thr 
            180                 185                 190         


Gly Asp Asn Phe Ser Asp Val Ala Ile Gln Gly Gly Ile Met Gly Ile 
        195                 200                 205             


Glu Ile Tyr Trp Asp Cys Asn Leu Asp Arg Trp Phe His His Cys His 
    210                 215                 220                 


Pro Lys Tyr Ser Phe Arg Arg Leu Asp Asp Lys Thr Thr Asn Val Ser 
225                 230                 235                 240 


Leu Tyr Pro Gly Tyr Asn Phe Arg Tyr Ala Lys Tyr Tyr Lys Glu Asn 
                245                 250                 255     


Asn Val Glu Lys Arg Thr Leu Ile Lys Val Phe Gly Ile Arg Phe Asp 
            260                 265                 270         


Ile Leu Val Phe Gly Thr Gly Gly Lys Phe Asp Ile Ile Gln Leu Val 
        275                 280                 285             


<210>  2835
<211>  98
<212>  PRT
<213>  Homo Sapiens

<400>  2835

Met Ala Ala Glu Pro Leu Thr Glu Leu Glu Glu Ser Ile Glu Thr Val 
1               5                   10                  15      


Val Thr Thr Phe Phe Thr Phe Ala Arg Gln Glu Gly Arg Lys Asp Ser 
            20                  25                  30          


Leu Ser Val Asn Glu Phe Lys Glu Leu Val Thr Gln Gln Leu Pro His 
        35                  40                  45              


Leu Leu Lys Asp Val Gly Ser Leu Asp Glu Lys Met Lys Ser Leu Asp 
    50                  55                  60                  


Val Asn Gln Asp Ser Glu Leu Lys Phe Asn Glu Tyr Trp Arg Leu Ile 
65                  70                  75                  80  


Gly Glu Leu Ala Lys Glu Ile Arg Lys Lys Lys Asp Leu Lys Ile Arg 
                85                  90                  95      


Lys Lys 
        


<210>  2836
<211>  282
<212>  PRT
<213>  Homo Sapiens

<400>  2836

Ala Pro Lys Asp Gly Val Thr Arg Pro Asp Ser Glu Val Gln His Gln 
1               5                   10                  15      


Leu Leu Pro Asn Pro Phe Gln Pro Gly Gln Glu Gln Leu Gly Leu Leu 
            20                  25                  30          


Gln Ser Tyr Leu Lys Gly Leu Gly Arg Thr Glu Val Gln Leu Glu His 
        35                  40                  45              


Leu Ser Arg Glu Gln Val Leu Leu Tyr Leu Phe Ala Leu His Asp Tyr 
    50                  55                  60                  


Asp Gln Ser Gly Gln Leu Asp Gly Leu Glu Leu Leu Ser Met Leu Thr 
65                  70                  75                  80  


Ala Ala Leu Ala Pro Gly Ala Ala Asn Ser Pro Thr Thr Asn Pro Val 
                85                  90                  95      


Ile Leu Ile Val Asp Lys Val Leu Glu Thr Gln Asp Leu Asn Gly Asp 
            100                 105                 110         


Gly Leu Met Thr Pro Ala Glu Leu Ile Asn Phe Pro Gly Val Ala Leu 
        115                 120                 125             


Arg His Val Glu Pro Gly Glu Pro Leu Ala Pro Ser Pro Gln Glu Pro 
    130                 135                 140                 


Gln Ala Val Gly Arg Gln Ser Leu Leu Ala Lys Ser Pro Leu Arg Gln 
145                 150                 155                 160 


Glu Thr Gln Glu Ala Pro Gly Pro Arg Glu Glu Ala Lys Gly Gln Val 
                165                 170                 175     


Glu Ala Arg Arg Glu Ser Leu Asp Pro Val Gln Glu Pro Gly Gly Gln 
            180                 185                 190         


Ala Glu Ala Asp Gly Asp Val Pro Gly Pro Arg Gly Glu Ala Glu Gly 
        195                 200                 205             


Gln Ala Glu Ala Lys Gly Asp Ala Pro Gly Pro Arg Gly Glu Ala Gly 
    210                 215                 220                 


Gly Gln Ala Glu Ala Glu Gly Asp Ala Pro Gly Pro Arg Gly Glu Ala 
225                 230                 235                 240 


Gly Gly Gln Ala Glu Ala Arg Glu Asn Gly Glu Glu Ala Lys Glu Leu 
                245                 250                 255     


Pro Gly Glu Thr Leu Glu Ser Lys Asn Thr Gln Asn Asp Phe Glu Val 
            260                 265                 270         


His Ile Val Gln Val Glu Asn Asp Glu Ile 
        275                 280         


<210>  2837
<211>  195
<212>  PRT
<213>  Homo Sapiens

<400>  2837

Cys Ser Cys Ala Pro Ala His Pro Gln Gln His Ile Cys His Ser Ala 
1               5                   10                  15      


Leu Val Ile Arg Ala Lys Ile Ser Ser Glu Lys Val Val Pro Ala Ser 
            20                  25                  30          


Ala Asp Pro Ala Asp Thr Glu Lys Met Leu Arg Tyr Glu Ile Lys Gln 
        35                  40                  45              


Ile Lys Met Phe Lys Gly Phe Glu Lys Val Lys Asp Val Gln Tyr Ile 
    50                  55                  60                  


Tyr Thr Pro Phe Asp Ser Ser Leu Cys Gly Val Lys Leu Glu Ala Asn 
65                  70                  75                  80  


Ser Gln Lys Gln Tyr Leu Leu Thr Gly Gln Val Leu Ser Asp Gly Lys 
                85                  90                  95      


Val Phe Ile His Leu Cys Asn Tyr Ile Glu Pro Trp Glu Asp Leu Ser 
            100                 105                 110         


Leu Val Gln Arg Glu Ser Leu Asn His His Tyr His Leu Asn Cys Gly 
        115                 120                 125             


Cys Gln Ile Thr Thr Cys Tyr Thr Val Pro Cys Thr Ile Ser Ala Pro 
    130                 135                 140                 


Asn Glu Cys Leu Trp Thr Asp Trp Leu Leu Glu Arg Lys Leu Tyr Gly 
145                 150                 155                 160 


Tyr Gln Ala Gln His Tyr Val Cys Met Lys His Val Asp Gly Thr Cys 
                165                 170                 175     


Ser Trp Tyr Arg Gly His Leu Pro Leu Arg Lys Glu Phe Val Asp Ile 
            180                 185                 190         


Val Gln Pro 
        195 


<210>  2838
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  2838

Leu Pro Thr Asn Pro Glu Glu Ser Trp Gln Val Tyr Ser Ser Ala Gln 
1               5                   10                  15      


Asp Ser Glu Gly Arg Cys Ile Cys Thr Val Val Ala Pro Gln Gln Thr 
            20                  25                  30          


Met Cys Ser Arg Asp Ala Arg Thr Lys Gln Leu Arg Gln Leu Leu Glu 
        35                  40                  45              


Lys Val Gln Asn Met Ser Gln Ser Ile Glu Val Leu Asp Arg Arg Thr 
    50                  55                  60                  


Gln Arg Asp Leu Gln Tyr Val Glu Lys Met Glu Asn Gln Met Lys Gly 
65                  70                  75                  80  


Leu Glu Ser Lys Phe Lys Gln Val Glu Glu Ser His Lys Gln His Leu 
                85                  90                  95      


Ala Arg Gln Phe Lys Ala Ile Lys Ala Lys Met Asp Glu Leu Arg Pro 
            100                 105                 110         


Leu Ile Pro Val Leu Glu Glu Tyr Lys Ala Asp Ala Lys Leu Val Leu 
        115                 120                 125             


Gln Phe Lys Glu Glu Val Gln Asn Leu Thr Ser Val Leu Asn Glu Leu 
    130                 135                 140                 


Gln Glu Glu Ile Gly Ala Tyr Asp Tyr Asp Glu Leu Gln Ser Arg Val 
145                 150                 155                 160 


Ser Asn Leu Glu Glu Arg Leu Arg Ala Cys Met Gln Lys Leu Ala Cys 
                165                 170                 175     


Gly Lys Leu Thr Gly Ile Ser Asp Pro Val Thr Val Lys Thr Ser Gly 
            180                 185                 190         


Ser Arg Phe Gly Ser Trp Met Thr Asp Pro Leu Ala Pro Glu Gly Asp 
        195                 200                 205             


Asn Arg Val Trp Tyr Met Asp Gly Tyr His Asn Asn Arg Phe Val Arg 
    210                 215                 220                 


Glu Tyr Lys Ser Met Val Asp Phe Met Asn Thr Asp Asn Phe Thr Ser 
225                 230                 235                 240 


His Arg Leu Pro His Pro Trp Ser Gly Thr Gly Gln Val Val Tyr Asn 
                245                 250                 255     


Gly Ser Ile Tyr Phe Asn Lys Phe Gln Ser His Ile Ile Ile Arg Phe 
            260                 265                 270         


Asp Leu Lys Thr Glu Thr Ile Leu Lys Thr Arg Ser Leu Asp Tyr Ala 
        275                 280                 285             


Gly Tyr Asn Asn Met Tyr His Tyr Ala Trp Gly Gly His Ser Asp Ile 
    290                 295                 300                 


Asp Leu Met Val Asp Glu Ser Gly Leu Trp Ala Val Tyr Ala Thr Asn 
305                 310                 315                 320 


Gln Asn Ala Gly Asn Ile Val Val Ser Arg Leu Asp Pro Val Ser Leu 
                325                 330                 335     


Gln Thr Leu Gln Thr Trp Asn Thr Ser Tyr Pro Lys Arg Ser Ala Gly 
            340                 345                 350         


Glu Ala Phe Ile Ile Cys Gly Thr Leu Tyr Val Thr Asn Gly Tyr Ser 
        355                 360                 365             


Gly Gly Thr Lys Val His Tyr Ala Tyr Gln Thr Asn Ala Ser Thr Tyr 
    370                 375                 380                 


Glu Tyr Ile Asp Ile Pro Phe Gln Asn Lys Tyr Ser His Ile Ser Met 
385                 390                 395                 400 


Leu Asp Tyr Asn Pro Lys Asp Arg Ala Leu Tyr Ala Trp Asn Asn Gly 
                405                 410                 415     


His Gln Ile Leu Tyr Asn Val Thr Leu Phe His Val Ile Arg Ser Asp 
            420                 425                 430         


Glu Leu 
        


<210>  2839
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  2839

Arg Gly Ala Ala Ser Ser Gly Asn Ala Thr Gly Pro Gly Pro Arg Ser 
1               5                   10                  15      


Ala Gly Gly Ser Ala Arg Arg Ser Ala Ala Val Thr Gly Pro Pro Pro 
            20                  25                  30          


Pro Leu Ser His Cys Gly Arg Ala Ala Pro Cys Glu Pro Leu Arg Tyr 
        35                  40                  45              


Asn Val Cys Leu Gly Ser Val Leu Pro Tyr Gly Ala Thr Ser Thr Leu 
    50                  55                  60                  


Leu Ala Gly Asp Ser Asp Ser Gln Glu Glu Ala His Gly Lys Leu Val 
65                  70                  75                  80  


Leu Trp Ser Gly Leu Arg Asn Ala Pro Arg Cys Trp Ala Val Ile Gln 
                85                  90                  95      


Pro Leu Leu Cys Ala Val Tyr Met Pro Lys Cys Glu Asn Asp Arg Val 
            100                 105                 110         


Glu Leu Pro Ser Arg Thr Leu Cys Gln Ala Thr Arg Gly Pro Cys Ala 
        115                 120                 125             


Ile Val Glu Arg Glu Arg Gly Trp Pro Asp Phe Leu Arg Cys Thr Pro 
    130                 135                 140                 


Asp Arg Phe Pro Glu Gly Cys Thr Asn Glu Val Gln Asn Ile Lys Phe 
145                 150                 155                 160 


Asn Ser Ser Gly Gln Cys Glu Val Pro Leu Val Arg Thr Asp Asn Pro 
                165                 170                 175     


Lys Ser Trp Tyr Glu Asp Val Glu Gly Cys Gly Ile Gln Cys Gln Asn 
            180                 185                 190         


Pro Leu Phe Thr Glu Ala Glu His Gln Asp Met His Ser Tyr 
        195                 200                 205     


<210>  2840
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2840

Ala Tyr Val Leu Phe Tyr Leu Phe Ala Ser Leu Thr Ser Asp Leu Pro 
1               5                   10                  15      


Trp Glu His Cys Gly Asn Trp Trp Asn Thr Glu Leu Cys Leu Glu His 
            20                  25                  30          


Arg Val Ser Lys Asp Gly Asn Gly Ala Leu Pro Leu Asn Leu Thr Cys 
        35                  40                  45              


Thr Val Ser Pro Ser Glu Glu Tyr Trp Ser Arg Tyr Val Leu His Ile 
    50                  55                  60                  


Gln Gly Ser Gln Gly Ile Gly Ser Pro Gly Glu Ile Arg 
65                  70                  75          


<210>  2841
<211>  239
<212>  PRT
<213>  Homo Sapiens

<400>  2841

Val Val Gly Gly Glu Asp Ala Arg Pro His Ser Trp Pro Trp Gln Ile 
1               5                   10                  15      


Ser Leu Gln Tyr Leu Lys Asn Asp Thr Trp Arg His Thr Cys Gly Gly 
            20                  25                  30          


Thr Leu Ile Ala Ser Asn Phe Val Leu Thr Ala Ala His Cys Ile Ser 
        35                  40                  45              


Asn Thr Arg Thr Tyr Arg Val Ala Val Gly Lys Asn Asn Leu Glu Val 
    50                  55                  60                  


Glu Asp Glu Glu Gly Ser Leu Phe Val Gly Val Asp Thr Ile His Val 
65                  70                  75                  80  


His Lys Arg Trp Asn Ala Leu Leu Leu Arg Asn Asp Ile Ala Leu Ile 
                85                  90                  95      


Lys Leu Ala Glu His Val Glu Leu Ser Asp Thr Ile Gln Val Ala Cys 
            100                 105                 110         


Leu Pro Glu Lys Asp Ser Leu Leu Pro Lys Asp Tyr Pro Cys Tyr Val 
        115                 120                 125             


Thr Gly Trp Gly Arg Leu Trp Thr Asn Gly Pro Ile Ala Asp Lys Leu 
    130                 135                 140                 


Gln Gln Gly Leu Gln Pro Val Val Asp His Ala Thr Cys Ser Arg Ile 
145                 150                 155                 160 


Asp Trp Trp Gly Phe Arg Val Lys Lys Thr Met Val Cys Ala Gly Gly 
                165                 170                 175     


Asp Gly Val Ile Ser Ala Cys Asn Gly Asp Ser Gly Gly Pro Leu Asn 
            180                 185                 190         


Cys Gln Leu Glu Asn Gly Ser Trp Glu Val Phe Gly Ile Val Ser Phe 
        195                 200                 205             


Gly Ser Arg Arg Gly Cys Asn Thr Arg Lys Lys Pro Val Val Tyr Thr 
    210                 215                 220                 


Arg Val Ser Ala Tyr Ile Asp Trp Ile Asn Glu Lys Met Gln Leu 
225                 230                 235                 


<210>  2842
<211>  69
<212>  PRT
<213>  Homo Sapiens

<400>  2842

Arg Gly Arg Asn Val Glu Asn Met Lys Ile Leu Arg Leu Met Leu Leu 
1               5                   10                  15      


His Ile Lys Tyr Leu Tyr Gly Ile Arg Val Glu Val Arg Gly Ala His 
            20                  25                  30          


His Phe Pro Pro Ser Gln Pro Tyr Val Val Val Ser Asn His Gln Ser 
        35                  40                  45              


Ser Leu Asp Leu Leu Gly Met Met Glu Val Leu Pro Gly Arg Cys Val 
    50                  55                  60                  


Pro Ile Ala Lys Arg 
65                  


<210>  2843
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  2843

Gln Arg Gly Pro Arg Gly Pro Tyr Pro Pro Gly Pro Leu Ala Pro Pro 
1               5                   10                  15      


Pro Pro Pro Arg Phe Pro Phe Gly Thr Gly Phe Val Pro Pro Pro His 
            20                  25                  30          


Pro Pro Pro Tyr Gly Pro Gly Arg Phe Pro Pro Pro Leu Ser Pro Pro 
        35                  40                  45              


Tyr Gly Pro Gly Arg Ile Pro Pro Ser Pro Pro Pro Pro Tyr Gly Pro 
    50                  55                  60                  


Gly Arg Ile Gln Ser His Ser Leu Pro Pro Pro Tyr Gly Pro Gly Tyr 
65                  70                  75                  80  


Pro Gln Pro Pro Ser Gln Pro Arg Pro Tyr Pro Pro Gly Pro Pro Phe 
                85                  90                  95      


Phe Pro Val Asn Ser Pro Thr Asp Pro Ala Leu Pro Thr Leu Ala Pro 
            100                 105                 110         


<210>  2844
<211>  137
<212>  PRT
<213>  Homo Sapiens

<400>  2844

Glu Leu Thr Glu Ala Gln Arg Arg Gly Leu Gln Val Ala Leu Glu Glu 
1               5                   10                  15      


Phe His Lys His Pro Pro Val Gln Trp Ala Phe Gln Glu Thr Ser Val 
            20                  25                  30          


Glu Ser Ala Val Asp Thr Pro Phe Pro Ala Gly Ile Phe Val Arg Leu 
        35                  40                  45              


Glu Phe Lys Leu Gln Gln Thr Ser Cys Arg Lys Arg Asp Trp Lys Lys 
    50                  55                  60                  


Pro Glu Cys Lys Val Arg Pro Asn Gly Arg Lys Arg Lys Cys Leu Ala 
65                  70                  75                  80  


Cys Ile Lys Leu Gly Ser Glu Asp Lys Val Leu Gly Arg Leu Val His 
                85                  90                  95      


Cys Pro Ile Glu Thr Gln Val Leu Arg Glu Ala Glu Glu His Gln Glu 
            100                 105                 110         


Thr Gln Cys Leu Arg Val Gln Arg Ala Gly Glu Asp Pro His Ser Phe 
        115                 120                 125             


Tyr Phe Pro Gly Gln Phe Ala Phe Ser 
    130                 135         


<210>  2845
<211>  472
<212>  PRT
<213>  Homo Sapiens

<400>  2845

Arg Thr Ala Gln Leu Arg Lys Ala Asn Asp Gln Ser Gly Arg Cys Gln 
1               5                   10                  15      


Tyr Thr Phe Ser Val Ala Ser Pro Asn Glu Ser Ser Cys Pro Glu Gln 
            20                  25                  30          


Ser Gln Ala Met Ser Val Ile His Asn Leu Gln Arg Asp Ser Ser Thr 
        35                  40                  45              


Gln Arg Leu Asp Leu Glu Ala Thr Lys Ala Arg Leu Ser Ser Leu Glu 
    50                  55                  60                  


Ser Leu Leu His Gln Leu Thr Leu Asp Gln Ala Ala Arg Pro Gln Glu 
65                  70                  75                  80  


Thr Gln Glu Gly Leu Gln Arg Glu Leu Gly Thr Leu Arg Arg Glu Arg 
                85                  90                  95      


Asp Gln Leu Glu Thr Gln Thr Arg Glu Leu Glu Thr Ala Tyr Ser Asn 
            100                 105                 110         


Leu Leu Arg Asp Lys Ser Val Leu Glu Glu Glu Lys Lys Arg Leu Arg 
        115                 120                 125             


Gln Glu Asn Glu Asn Leu Ala Arg Arg Leu Glu Ser Ser Ser Gln Glu 
    130                 135                 140                 


Val Ala Arg Leu Arg Arg Gly Gln Cys Pro Gln Thr Arg Asp Thr Ala 
145                 150                 155                 160 


Arg Ala Val Pro Pro Gly Ser Arg Glu Val Ser Thr Trp Asn Leu Asp 
                165                 170                 175     


Thr Leu Ala Phe Gln Glu Leu Lys Ser Glu Leu Thr Glu Val Pro Ala 
            180                 185                 190         


Ser Arg Ile Leu Lys Glu Ser Pro Ser Gly Tyr Leu Arg Ser Gly Glu 
        195                 200                 205             


Gly Asp Thr Gly Cys Gly Glu Leu Val Trp Val Gly Glu Pro Leu Thr 
    210                 215                 220                 


Leu Arg Thr Ala Glu Thr Ile Thr Gly Lys Tyr Gly Val Trp Met Arg 
225                 230                 235                 240 


Asp Pro Lys Pro Thr Tyr Pro Tyr Thr Gln Glu Thr Thr Trp Arg Ile 
                245                 250                 255     


Asp Thr Val Gly Thr Asp Val Arg Gln Val Phe Glu Tyr Asp Leu Ile 
            260                 265                 270         


Ser Gln Phe Met Gln Gly Tyr Pro Ser Lys Val His Ile Leu Pro Arg 
        275                 280                 285             


Pro Leu Glu Ser Thr Gly Ala Val Val Tyr Ser Gly Ser Leu Tyr Phe 
    290                 295                 300                 


Gln Gly Ala Glu Ser Arg Thr Val Ile Arg Tyr Glu Leu Asn Thr Glu 
305                 310                 315                 320 


Thr Val Lys Ala Glu Lys Glu Ile Pro Gly Ala Gly Tyr His Gly Gln 
                325                 330                 335     


Phe Pro Tyr Ser Trp Gly Gly Tyr Thr Asp Ile Asp Leu Ala Val Asp 
            340                 345                 350         


Glu Ala Gly Leu Trp Val Ile Tyr Ser Thr Asp Glu Ala Lys Gly Ala 
        355                 360                 365             


Ile Val Leu Ser Lys Leu Asn Pro Glu Asn Leu Glu Leu Glu Gln Thr 
    370                 375                 380                 


Trp Glu Thr Asn Ile Arg Lys Gln Ser Val Ala Asn Ala Phe Ile Ile 
385                 390                 395                 400 


Cys Gly Thr Leu Tyr Thr Val Ser Ser Tyr Thr Ser Ala Asp Ala Thr 
                405                 410                 415     


Val Asn Phe Ala Tyr Asp Thr Gly Thr Gly Ile Ser Lys Thr Leu Thr 
            420                 425                 430         


Ile Pro Phe Lys Asn Arg Tyr Lys Tyr Ser Ser Met Ile Asp Tyr Asn 
        435                 440                 445             


Pro Leu Glu Lys Lys Leu Phe Ala Trp Asp Asn Leu Asn Met Val Thr 
    450                 455                 460                 


Tyr Asp Ile Lys Leu Ser Lys Met 
465                 470         


<210>  2846
<211>  330
<212>  PRT
<213>  Homo Sapiens

<400>  2846

Gly Trp Thr Val Ala Gly Gln Phe Gln Glu Lys Lys Arg Phe Thr Glu 
1               5                   10                  15      


Glu Val Ile Glu Tyr Phe Gln Lys Lys Val Ser Pro Val His Leu Lys 
            20                  25                  30          


Ile Leu Leu Thr Ser Asp Glu Ala Trp Lys Arg Phe Val Arg Val Ala 
        35                  40                  45              


Glu Leu Pro Arg Glu Glu Ala Asp Ala Leu Tyr Glu Ala Leu Lys Asn 
    50                  55                  60                  


Leu Thr Pro Tyr Val Ala Ile Glu Asp Lys Asp Met Gln Gln Lys Glu 
65                  70                  75                  80  


Gln Gln Phe Arg Glu Trp Phe Leu Lys Glu Phe Pro Gln Ile Arg Trp 
                85                  90                  95      


Lys Ile Gln Glu Ser Ile Glu Arg Leu Arg Val Ile Ala Asn Glu Ile 
            100                 105                 110         


Glu Lys Val His Arg Gly Cys Val Ile Ala Asn Val Val Ser Gly Ser 
        115                 120                 125             


Thr Gly Ile Leu Ser Val Ile Gly Val Met Leu Ala Pro Phe Thr Ala 
    130                 135                 140                 


Gly Leu Ser Leu Ser Ile Thr Ala Ala Gly Val Gly Leu Gly Ile Ala 
145                 150                 155                 160 


Ser Ala Thr Ala Gly Ile Ala Ser Ser Ile Val Glu Asn Thr Tyr Thr 
                165                 170                 175     


Arg Ser Ala Glu Leu Thr Ala Ser Arg Leu Thr Ala Thr Ser Thr Asp 
            180                 185                 190         


Gln Leu Glu Ala Leu Arg Asp Ile Leu Arg Asp Ile Thr Pro Asn Val 
        195                 200                 205             


Leu Ser Phe Ala Leu Asp Phe Asp Glu Ala Thr Lys Met Ile Ala Asn 
    210                 215                 220                 


Asp Val His Thr Leu Arg Arg Ser Lys Ala Thr Val Gly Arg Pro Leu 
225                 230                 235                 240 


Ile Ala Trp Arg Tyr Val Pro Ile Asn Val Val Glu Thr Leu Arg Thr 
                245                 250                 255     


Arg Gly Ala Pro Thr Arg Ile Val Arg Lys Val Ala Arg Asn Leu Gly 
            260                 265                 270         


Lys Ala Thr Ser Gly Val Leu Val Val Leu Asp Val Val Asn Leu Val 
        275                 280                 285             


Gln Asp Ser Leu Asp Leu His Lys Gly Ala Lys Ser Glu Ser Ala Glu 
    290                 295                 300                 


Ser Leu Arg Gln Trp Ala Gln Glu Leu Glu Glu Asn Leu Asn Glu Leu 
305                 310                 315                 320 


Thr His Ile His Gln Ser Leu Lys Ala Gly 
                325                 330 


<210>  2847
<211>  88
<212>  PRT
<213>  Homo Sapiens

<400>  2847

Gln Cys Ser Leu Asp Ser Val Met Asp Lys Lys Ile Lys Asp Val Leu 
1               5                   10                  15      


Asn Ser Leu Glu Tyr Ser Pro Ser Pro Ile Ser Lys Lys Leu Ser Cys 
            20                  25                  30          


Ala Ser Val Lys Ser Gln Gly Arg Pro Ser Ser Cys Pro Ala Gly Met 
        35                  40                  45              


Ala Val Thr Gly Cys Ala Cys Gly Tyr Gly Cys Gly Ser Trp Asp Val 
    50                  55                  60                  


Gln Leu Glu Thr Thr Cys His Cys Gln Cys Ser Val Val Asp Trp Thr 
65                  70                  75                  80  


Thr Ala Arg Cys Cys His Leu Thr 
                85              


<210>  2848
<211>  412
<212>  PRT
<213>  Homo Sapiens

<400>  2848

Ala Ala Ala Ala Val Ala Ala Ala Gly Gly Arg Ser Asp Gly Gly Asn 
1               5                   10                  15      


Phe Leu Asp Asp Lys Gln Trp Leu Thr Thr Ile Ser Gln Tyr Asp Lys 
            20                  25                  30          


Glu Val Gly Gln Trp Asn Lys Phe Arg Asp Asp Asp Tyr Phe Arg Thr 
        35                  40                  45              


Trp Ser Pro Gly Lys Pro Phe Asp Gln Ala Leu Asp Pro Ala Lys Asp 
    50                  55                  60                  


Pro Cys Leu Lys Met Lys Cys Ser Arg His Lys Val Cys Ile Ala Gln 
65                  70                  75                  80  


Asp Ser Gln Thr Ala Val Cys Ile Ser His Arg Arg Leu Thr His Arg 
                85                  90                  95      


Met Lys Glu Ala Gly Val Asp His Arg Gln Trp Arg Gly Pro Ile Leu 
            100                 105                 110         


Ser Thr Cys Lys Gln Cys Pro Val Val Tyr Pro Ser Pro Val Cys Gly 
        115                 120                 125             


Ser Asp Gly His Thr Tyr Ser Phe Gln Cys Lys Leu Glu Tyr Gln Ala 
    130                 135                 140                 


Cys Val Leu Gly Lys Gln Ile Ser Val Lys Cys Glu Gly His Cys Pro 
145                 150                 155                 160 


Cys Pro Ser Asp Lys Pro Thr Ser Thr Ser Arg Asn Val Lys Arg Ala 
                165                 170                 175     


Cys Ser Asp Leu Glu Phe Arg Glu Val Ala Asn Arg Leu Arg Asp Trp 
            180                 185                 190         


Phe Lys Ala Leu His Glu Ser Gly Ser Gln Asn Lys Lys Thr Lys Thr 
        195                 200                 205             


Leu Leu Arg Pro Glu Arg Ser Arg Phe Asp Thr Ser Ile Leu Pro Ile 
    210                 215                 220                 


Cys Lys Asp Ser Leu Gly Trp Met Phe Asn Arg Leu Asp Thr Asn Tyr 
225                 230                 235                 240 


Asp Leu Leu Leu Asp Gln Ser Glu Leu Arg Ser Ile Tyr Leu Asp Lys 
                245                 250                 255     


Asn Glu Gln Cys Thr Lys Ala Phe Phe Asn Ser Cys Asp Thr Tyr Lys 
            260                 265                 270         


Asp Ser Leu Ile Ser Asn Asn Glu Trp Cys Tyr Cys Phe Gln Arg Gln 
        275                 280                 285             


Gln Asp Pro Pro Cys Gln Thr Glu Leu Ser Asn Ile Gln Lys Arg Gln 
    290                 295                 300                 


Gly Val Lys Lys Leu Leu Gly Gln Tyr Ile Pro Leu Cys Asp Glu Asp 
305                 310                 315                 320 


Gly Tyr Tyr Lys Pro Thr Gln Cys His Gly Ser Val Gly Gln Cys Trp 
                325                 330                 335     


Cys Val Asp Arg Tyr Gly Asn Glu Val Met Gly Ser Arg Ile Asn Gly 
            340                 345                 350         


Val Ala Asp Cys Ala Ile Asp Phe Glu Ile Ser Gly Asp Phe Ala Ser 
        355                 360                 365             


Gly Asp Phe His Glu Trp Thr Asp Asp Glu Asp Asp Glu Asp Asp Ile 
    370                 375                 380                 


Met Asn Asp Glu Asp Glu Ile Glu Asp Asp Asp Glu Asp Glu Gly Asp 
385                 390                 395                 400 


Asp Asp Asp Gly Gly Asp Asp His Asp Val Tyr Ile 
                405                 410         


<210>  2849
<211>  190
<212>  PRT
<213>  Homo Sapiens

<400>  2849

Gln Gly Trp Gln Ala Phe Lys Asn Asp Ala Thr Glu Ile Ile Pro Glu 
1               5                   10                  15      


Leu Gly Glu Tyr Pro Glu Pro Pro Pro Glu Leu Glu Asn Asn Lys Thr 
            20                  25                  30          


Met Asn Arg Ala Glu Asn Gly Gly Arg Pro Pro His His Pro Phe Glu 
        35                  40                  45              


Thr Lys Asp Val Ser Glu Tyr Ser Cys Arg Glu Leu His Phe Thr Arg 
    50                  55                  60                  


Tyr Val Thr Asp Gly Pro Cys Arg Ser Ala Lys Pro Val Thr Glu Leu 
65                  70                  75                  80  


Val Cys Ser Gly Gln Cys Gly Pro Ala Arg Leu Leu Pro Asn Ala Ile 
                85                  90                  95      


Gly Arg Gly Lys Trp Trp Arg Pro Ser Gly Pro Asp Phe Arg Cys Ile 
            100                 105                 110         


Pro Asp Arg Tyr Arg Ala Gln Arg Val Gln Leu Leu Cys Pro Gly Gly 
        115                 120                 125             


Glu Ala Pro Arg Ala Arg Lys Val Arg Leu Val Ala Ser Cys Lys Cys 
    130                 135                 140                 


Lys Arg Leu Thr Arg Phe His Asn Gln Ser Glu Leu Lys Asp Phe Gly 
145                 150                 155                 160 


Thr Glu Ala Ala Arg Pro Gln Lys Gly Arg Lys Pro Arg Pro Arg Ala 
                165                 170                 175     


Arg Ser Ala Lys Ala Asn Gln Ala Glu Leu Glu Asn Ala Tyr 
            180                 185                 190 


<210>  2850
<211>  249
<212>  PRT
<213>  Homo Sapiens

<400>  2850

Cys Gln Leu Pro Ser Glu Trp Arg Pro Leu Ser Glu Gly Cys Arg Ala 
1               5                   10                  15      


Glu Leu Ala Glu Thr Ile Val Tyr Ala Arg Val Leu Ala Leu His Pro 
            20                  25                  30          


Glu Ala Pro Gly Leu Tyr Asn His Leu Pro Trp Gln Tyr His Ala Gly 
        35                  40                  45              


Gln Gly Gly Leu Phe Tyr Ser Ala Glu Val Glu Met Leu Cys Asp Gln 
    50                  55                  60                  


Ala Trp Gly Ser Met Leu Glu Val Pro Ala Gly Ser Arg Leu Asn Leu 
65                  70                  75                  80  


Thr Gly Leu Gly Tyr Phe Ser Cys His Ser His Thr Val Val Gln Asp 
                85                  90                  95      


Tyr Ser Tyr Phe Phe Phe Leu Arg Met Asp Glu Asn Tyr Asn Leu Leu 
            100                 105                 110         


Pro His Gly Val Asn Phe Gln Asp Ala Ile Phe Pro Asp Thr Gln Glu 
        115                 120                 125             


Asn Arg Arg Met Phe Ser Ser Leu Phe Gln Phe Ser Asn Cys Ser Gln 
    130                 135                 140                 


Gly Gln Gln Leu Ala Thr Phe Ser Ser Asp Trp Glu Ile Gln Glu Asp 
145                 150                 155                 160 


Ser Arg Leu Met Cys Ser Ser Val Gln Lys Ala Leu Phe Glu Glu Glu 
                165                 170                 175     


Asp His Val Lys Lys Leu Gln Gln Lys Val Ala Thr Leu Glu Lys Arg 
            180                 185                 190         


Asn Arg Gln Leu Arg Glu Arg Val Lys Lys Val Lys Arg Ser Leu Arg 
        195                 200                 205             


Gln Ala Arg Lys Lys Gly Arg His Leu Glu Leu Ala Asn Gln Lys Leu 
    210                 215                 220                 


Ser Glu Lys Leu Ala Ala Gly Ala Leu Pro His Ile Asn Ala Arg Gly 
225                 230                 235                 240 


Pro Val Arg Pro Pro Tyr Leu Arg Gly 
                245                 


<210>  2851
<211>  1087
<212>  PRT
<213>  Homo Sapiens

<400>  2851

Ala Thr Arg Val Tyr Tyr Leu Gly Ile Arg Asp Val Gln Trp Asn Tyr 
1               5                   10                  15      


Ala Pro Lys Gly Arg Asn Val Ile Thr Asn Gln Pro Leu Asp Ser Asp 
            20                  25                  30          


Ile Val Ala Ser Ser Phe Leu Lys Ser Asp Lys Asn Arg Ile Gly Gly 
        35                  40                  45              


Thr Tyr Lys Lys Thr Ile Tyr Lys Glu Tyr Lys Asp Asp Ser Tyr Thr 
    50                  55                  60                  


Asp Glu Val Ala Gln Pro Ala Trp Leu Gly Phe Leu Gly Pro Val Leu 
65                  70                  75                  80  


Gln Ala Glu Val Gly Asp Val Ile Leu Ile His Leu Lys Asn Phe Ala 
                85                  90                  95      


Thr Arg Pro Tyr Thr Ile His Pro His Gly Val Phe Tyr Glu Lys Asp 
            100                 105                 110         


Ser Glu Gly Ser Leu Tyr Pro Asp Gly Ser Ser Gly Pro Leu Lys Ala 
        115                 120                 125             


Asp Asp Ser Val Pro Pro Gly Gly Ser His Ile Tyr Asn Trp Thr Ile 
    130                 135                 140                 


Pro Glu Gly His Ala Pro Thr Asp Ala Asp Pro Ala Cys Leu Thr Trp 
145                 150                 155                 160 


Ile Tyr His Ser His Val Asp Ala Pro Arg Asp Ile Ala Thr Gly Leu 
                165                 170                 175     


Ile Gly Pro Leu Ile Thr Cys Lys Arg Gly Ala Leu Asp Gly Asn Ser 
            180                 185                 190         


Pro Pro Gln Arg Gln Asp Val Asp His Asp Phe Phe Leu Leu Phe Ser 
        195                 200                 205             


Val Val Asp Glu Asn Leu Ser Trp His Leu Asn Glu Asn Ile Ala Thr 
    210                 215                 220                 


Tyr Cys Ser Asp Pro Ala Ser Val Asp Lys Glu Asp Glu Thr Phe Gln 
225                 230                 235                 240 


Glu Ser Asn Arg Met His Ala Ile Asn Gly Phe Val Phe Gly Asn Leu 
                245                 250                 255     


Pro Glu Leu Asn Met Cys Ala Gln Lys Arg Val Ala Trp His Leu Phe 
            260                 265                 270         


Gly Met Gly Asn Glu Ile Asp Val His Thr Ala Phe Phe His Gly Gln 
        275                 280                 285             


Met Leu Thr Thr Arg Gly His His Thr Asp Val Ala Asn Ile Phe Pro 
    290                 295                 300                 


Ala Thr Phe Val Thr Ala Glu Met Val Pro Trp Glu Pro Gly Thr Trp 
305                 310                 315                 320 


Leu Ile Ser Cys Gln Val Asn Ser His Phe Arg Asp Gly Met Gln Ala 
                325                 330                 335     


Leu Tyr Lys Val Lys Ser Cys Ser Met Ala Pro Pro Val Asp Leu Leu 
            340                 345                 350         


Thr Gly Lys Val Arg Gln Tyr Phe Ile Glu Ala His Glu Ile Gln Trp 
        355                 360                 365             


Asp Tyr Gly Pro Met Gly His Asp Gly Ser Thr Gly Lys Asn Leu Arg 
    370                 375                 380                 


Glu Pro Gly Ser Ile Ser Asp Lys Phe Phe Gln Lys Ser Ser Ser Arg 
385                 390                 395                 400 


Ile Gly Gly Thr Tyr Trp Lys Val Arg Tyr Glu Ala Phe Gln Asp Glu 
                405                 410                 415     


Thr Phe Gln Glu Lys Met His Leu Glu Glu Asp Arg His Leu Gly Ile 
            420                 425                 430         


Leu Gly Pro Val Ile Arg Ala Glu Val Gly Asp Thr Ile Gln Val Val 
        435                 440                 445             


Phe Tyr Asn Arg Ala Ser Gln Pro Phe Ser Met Gln Pro His Gly Val 
    450                 455                 460                 


Phe Tyr Glu Lys Asp Tyr Glu Gly Thr Val Tyr Asn Asp Gly Ser Ser 
465                 470                 475                 480 


Tyr Pro Gly Leu Val Ala Lys Pro Phe Glu Lys Val Thr Tyr Arg Trp 
                485                 490                 495     


Thr Val Pro Pro His Ala Gly Pro Thr Ala Gln Asp Pro Ala Cys Leu 
            500                 505                 510         


Thr Trp Met Tyr Phe Ser Ala Ala Asp Pro Ile Arg Asp Thr Asn Ser 
        515                 520                 525             


Gly Leu Val Gly Pro Leu Leu Val Cys Arg Ala Gly Ala Leu Gly Ala 
    530                 535                 540                 


Asp Gly Lys Gln Lys Gly Val Asp Lys Glu Phe Phe Leu Leu Phe Thr 
545                 550                 555                 560 


Val Leu Asp Glu Asn Lys Ser Trp Tyr Ser Asn Ala Asn Gln Ala Ala 
                565                 570                 575     


Ala Met Leu Asp Phe Arg Leu Leu Ser Glu Asp Ile Glu Gly Phe Gln 
            580                 585                 590         


Asp Ser Asn Arg Met His Ala Ile Asn Gly Phe Leu Phe Ser Asn Leu 
        595                 600                 605             


Pro Arg Leu Asp Met Cys Lys Gly Asp Thr Val Ala Trp His Leu Leu 
    610                 615                 620                 


Gly Leu Gly Thr Glu Thr Asp Val His Gly Val Met Phe Gln Gly Asn 
625                 630                 635                 640 


Thr Val Gln Leu Gln Gly Met Arg Lys Gly Ala Ala Met Leu Phe Pro 
                645                 650                 655     


His Thr Phe Val Met Ala Ile Met Gln Pro Asp Asn Leu Gly Thr Phe 
            660                 665                 670         


Glu Ile Tyr Cys Gln Ala Gly Ser His Arg Glu Ala Gly Met Arg Ala 
        675                 680                 685             


Ile Tyr Asn Val Ser Gln Cys Pro Gly His Gln Ala Thr Pro Arg Gln 
    690                 695                 700                 


Arg Tyr Gln Ala Ala Arg Ile Tyr Tyr Ile Met Ala Glu Glu Val Glu 
705                 710                 715                 720 


Trp Asp Tyr Cys Pro Asp Arg Ser Trp Glu Arg Glu Trp His Asn Gln 
                725                 730                 735     


Ser Glu Lys Asp Ser Tyr Gly Tyr Ile Phe Leu Ser Asn Lys Asp Gly 
            740                 745                 750         


Leu Leu Gly Ser Arg Tyr Lys Lys Ala Val Phe Arg Glu Tyr Thr Asp 
        755                 760                 765             


Gly Thr Phe Arg Ile Pro Arg Pro Arg Thr Gly Pro Glu Glu His Leu 
    770                 775                 780                 


Gly Ile Leu Gly Pro Leu Ile Lys Gly Glu Val Gly Asp Ile Leu Thr 
785                 790                 795                 800 


Val Val Phe Lys Asn Asn Ala Ser Arg Pro Tyr Ser Val His Ala His 
                805                 810                 815     


Gly Val Leu Glu Ser Thr Thr Val Trp Pro Leu Ala Ala Glu Pro Gly 
            820                 825                 830         


Glu Val Val Thr Tyr Gln Trp Asn Ile Pro Glu Arg Ser Gly Pro Gly 
        835                 840                 845             


Pro Asn Asp Ser Ala Cys Val Ser Trp Ile Tyr Tyr Ser Ala Val Asp 
    850                 855                 860                 


Pro Ile Lys Asp Met Tyr Ser Gly Leu Val Gly Pro Leu Ala Ile Cys 
865                 870                 875                 880 


Gln Lys Gly Ile Leu Glu Pro His Gly Gly Arg Ser Asp Met Asp Arg 
                885                 890                 895     


Glu Phe Ala Leu Leu Phe Leu Ile Phe Asp Glu Asn Lys Ser Trp Tyr 
            900                 905                 910         


Leu Glu Glu Asn Val Ala Thr His Gly Ser Gln Asp Pro Gly Ser Ile 
        915                 920                 925             


Asn Leu Gln Asp Glu Thr Phe Leu Glu Ser Asn Lys Met His Ala Ile 
    930                 935                 940                 


Asn Gly Lys Leu Tyr Ala Asn Leu Arg Gly Leu Thr Met Tyr Gln Gly 
945                 950                 955                 960 


Glu Arg Val Ala Trp Tyr Met Leu Ala Met Gly Gln Asp Val Asp Leu 
                965                 970                 975     


His Thr Ile His Phe His Ala Glu Ser Phe Leu Tyr Arg Asn Gly Glu 
            980                 985                 990         


Asn Tyr Arg Ala Asp Val Val Asp  Leu Phe Pro Gly Thr  Phe Glu Val 
        995                 1000                 1005             


Val Glu  Met Val Ala Ser Asn  Pro Gly Thr Trp Leu  Met His Cys 
    1010                 1015                 1020             


His Val  Thr Asp His Val His  Ala Gly Met Glu Thr  Leu Phe Thr 
    1025                 1030                 1035             


Val Phe  Ser Arg Thr Glu His  Leu Ser Pro Leu Thr  Val Ile Thr 
    1040                 1045                 1050             


Lys Glu  Thr Glu Lys Ala Val  Pro Pro Arg Asp Ile  Glu Glu Gly 
    1055                 1060                 1065             


Asn Val  Lys Met Leu Gly Met  Gln Ile Pro Ile Lys  Asn Val Glu 
    1070                 1075                 1080             


Met Leu  Ala Ser 
    1085         


<210>  2852
<211>  828
<212>  PRT
<213>  Homo Sapiens

<400>  2852

Asn Lys Ala Asn Lys His Lys Pro Trp Ile Glu Ala Glu Tyr Gln Gly 
1               5                   10                  15      


Ile Val Met Glu Asn Asp Asn Thr Val Leu Leu Asn Pro Pro Leu Phe 
            20                  25                  30          


Ala Leu Asp Lys Asp Ala Pro Leu Arg Tyr Ala Gly Glu Ile Cys Gly 
        35                  40                  45              


Phe Arg Leu His Gly Ser Gly Val Pro Phe Glu Ala Val Ile Leu Asp 
    50                  55                  60                  


Lys Ala Thr Gly Glu Gly Leu Ile Arg Ala Lys Glu Pro Val Asp Cys 
65                  70                  75                  80  


Glu Ala Gln Lys Glu His Thr Phe Thr Ile Gln Ala Tyr Asp Cys Gly 
                85                  90                  95      


Glu Gly Pro Asp Gly Ala Asn Thr Lys Lys Ser His Lys Ala Thr Val 
            100                 105                 110         


His Val Arg Val Asn Asp Val Asn Glu Phe Ala Pro Val Phe Val Glu 
        115                 120                 125             


Arg Leu Tyr Arg Ala Ala Val Thr Glu Gly Lys Leu Tyr Asp Arg Ile 
    130                 135                 140                 


Leu Arg Val Glu Ala Ile Asp Gly Asp Cys Ser Pro Gln Tyr Ser Gln 
145                 150                 155                 160 


Ile Cys Tyr Tyr Glu Ile Leu Thr Pro Asn Thr Pro Phe Leu Ile Asp 
                165                 170                 175     


Asn Asp Gly Asn Ile Glu Asn Thr Glu Lys Leu Gln Tyr Ser Gly Glu 
            180                 185                 190         


Arg Leu Tyr Lys Phe Thr Val Thr Ala Tyr Asp Cys Gly Lys Lys Arg 
        195                 200                 205             


Ala Ala Asp Asp Ala Glu Val Glu Ile Gln Val Lys Pro Thr Cys Lys 
    210                 215                 220                 


Pro Ser Trp Gln Gly Trp Asn Lys Arg Ile Glu Tyr Ala Pro Gly Ala 
225                 230                 235                 240 


Gly Ser Leu Ala Leu Phe Pro Gly Ile Arg Leu Glu Thr Cys Asp Glu 
                245                 250                 255     


Pro Leu Trp Asn Ile Gln Ala Thr Ile Glu Leu Gln Thr Ser His Val 
            260                 265                 270         


Ala Lys Gly Cys Asp Arg Asp Asn Tyr Ser Glu Arg Ala Leu Arg Lys 
        275                 280                 285             


Leu Cys Gly Ala Ala Thr Gly Glu Val Asp Leu Leu Pro Met Pro Gly 
    290                 295                 300                 


Pro Asn Ala Asn Trp Thr Ala Gly Leu Ser Val His Tyr Ser Gln Asp 
305                 310                 315                 320 


Ser Ser Leu Ile Tyr Trp Phe Asn Gly Thr Gln Ala Val Gln Val Pro 
                325                 330                 335     


Leu Gly Gly Pro Ser Gly Leu Gly Ser Gly Pro Gln Asp Ser Leu Ser 
            340                 345                 350         


Asp His Phe Thr Leu Ser Phe Trp Met Lys His Gly Val Thr Pro Asn 
        355                 360                 365             


Lys Gly Lys Lys Glu Glu Glu Thr Ile Val Cys Asn Thr Val Gln Asn 
    370                 375                 380                 


Glu Asp Gly Phe Ser His Tyr Ser Leu Thr Val His Gly Cys Arg Ile 
385                 390                 395                 400 


Ala Phe Leu Tyr Trp Pro Leu Leu Glu Ser Ala Arg Pro Val Lys Phe 
                405                 410                 415     


Leu Trp Lys Leu Glu Gln Val Cys Asp Asp Glu Trp His His Tyr Ala 
            420                 425                 430         


Leu Asn Leu Glu Phe Pro Thr Val Thr Leu Tyr Thr Asp Gly Ile Ser 
        435                 440                 445             


Phe Asp Pro Ala Leu Ile His Asp Asn Gly Leu Ile His Pro Pro Arg 
    450                 455                 460                 


Arg Glu Pro Ala Leu Met Ile Gly Ala Cys Trp Thr Glu Glu Lys Asn 
465                 470                 475                 480 


Lys Glu Lys Glu Lys Gly Asp Asn Ser Thr Asp Thr Thr Gln Gly Asp 
                485                 490                 495     


Pro Leu Ser Ile His His Tyr Phe His Gly Tyr Leu Ala Gly Phe Ser 
            500                 505                 510         


Val Arg Ser Gly Arg Leu Glu Ser Arg Glu Val Ile Glu Cys Leu Tyr 
        515                 520                 525             


Ala Cys Arg Glu Gly Leu Asp Tyr Arg Asp Phe Glu Ser Leu Gly Lys 
    530                 535                 540                 


Gly Met Lys Val His Val Asn Pro Ser Gln Ser Leu Leu Thr Leu Glu 
545                 550                 555                 560 


Gly Asp Asp Val Glu Thr Phe Asn His Ala Leu Gln His Val Ala Tyr 
                565                 570                 575     


Met Asn Thr Leu Arg Phe Ala Thr Pro Gly Val Arg Pro Leu Arg Leu 
            580                 585                 590         


Thr Thr Ala Val Lys Cys Phe Ser Glu Glu Ser Cys Val Ser Ile Pro 
        595                 600                 605             


Glu Val Glu Gly Tyr Val Val Val Leu Gln Pro Asp Ala Pro Gln Ile 
    610                 615                 620                 


Leu Leu Ser Gly Thr Ala His Phe Ala Arg Pro Ala Val Asp Phe Glu 
625                 630                 635                 640 


Gly Thr Asn Gly Val Pro Leu Phe Pro Asp Leu Gln Ile Thr Cys Ser 
                645                 650                 655     


Ile Ser His Gln Val Glu Ala Lys Lys Asp Glu Ser Trp Gln Gly Thr 
            660                 665                 670         


Val Thr Asp Thr Arg Met Ser Asp Glu Ile Val His Asn Leu Asp Gly 
        675                 680                 685             


Cys Glu Ile Ser Leu Val Gly Asp Asp Leu Asp Pro Glu Arg Glu Ser 
    690                 695                 700                 


Leu Leu Leu Asp Thr Thr Ser Leu Gln Gln Arg Gly Leu Glu Leu Thr 
705                 710                 715                 720 


Asn Thr Ser Ala Tyr Leu Thr Ile Ala Gly Val Glu Ser Ile Thr Val 
                725                 730                 735     


Tyr Glu Glu Ile Leu Arg Gln Ala Arg Tyr Arg Leu Arg His Gly Ala 
            740                 745                 750         


Ala Leu Tyr Thr Arg Lys Phe Arg Leu Ser Cys Ser Glu Met Asn Gly 
        755                 760                 765             


Arg Tyr Ser Ser Asn Glu Phe Ile Val Glu Val Asn Val Leu His Ser 
    770                 775                 780                 


Met Asn Arg Val Ala His Pro Ser His Val Leu Ser Ser Gln Gln Phe 
785                 790                 795                 800 


Leu His Arg Gly His Gln Pro Pro Pro Glu Met Ala Gly His Ser Leu 
                805                 810                 815     


Ala Ser Ser His Arg Asn Ser Met Ile Pro Ser Ala 
            820                 825             


<210>  2853
<211>  61
<212>  PRT
<213>  Homo Sapiens

<400>  2853

Glu Gly Ile Leu Gly Lys Pro Cys Pro Lys Ile Lys Val Glu Cys Glu 
1               5                   10                  15      


Val Glu Glu Ile Asp Gln Cys Thr Lys Pro Arg Asp Cys Pro Glu Asn 
            20                  25                  30          


Met Lys Cys Cys Pro Phe Ser Arg Gly Lys Lys Cys Leu Asp Phe Arg 
        35                  40                  45              


Lys Val Ser Leu Thr Leu Tyr His Lys Glu Glu Leu Glu 
    50                  55                  60      


<210>  2854
<211>  326
<212>  PRT
<213>  Homo Sapiens

<400>  2854

Arg Pro Ala Asn His Ser Ser Thr Arg Glu Arg Val Ala Asn Arg Glu 
1               5                   10                  15      


Glu Asn Glu Ile Leu Pro Pro Asp His Leu Asn Gly Val Lys Leu Glu 
            20                  25                  30          


Met Asp Gly His Leu Asn Arg Gly Phe His Gln Glu Val Phe Leu Gly 
        35                  40                  45              


Lys Asp Leu Gly Gly Phe Asp Glu Asp Ala Glu Pro Arg Arg Ser Arg 
    50                  55                  60                  


Arg Lys Leu Met Val Ile Phe Ser Lys Val Asp Val Asn Thr Asp Arg 
65                  70                  75                  80  


Lys Ile Ser Ala Lys Glu Met Gln Arg Trp Ile Met Glu Lys Thr Ala 
                85                  90                  95      


Glu His Phe Gln Glu Ala Met Glu Glu Ser Lys Thr His Phe Arg Ala 
            100                 105                 110         


Val Asp Pro Asp Gly Asp Gly His Val Ser Trp Asp Glu Tyr Lys Val 
        115                 120                 125             


Lys Phe Leu Ala Ser Lys Gly His Ser Glu Lys Glu Val Ala Asp Ala 
    130                 135                 140                 


Ile Arg Leu Asn Glu Glu Leu Lys Val Asp Glu Glu Thr Gln Glu Val 
145                 150                 155                 160 


Leu Glu Asn Leu Lys Asp Arg Trp Tyr Gln Ala Asp Ser Pro Pro Ala 
                165                 170                 175     


Asp Leu Leu Leu Thr Glu Glu Glu Phe Leu Ser Phe Leu His Pro Glu 
            180                 185                 190         


His Ser Arg Gly Met Leu Arg Phe Met Val Lys Glu Ile Val Arg Asp 
        195                 200                 205             


Leu Asp Gln Asp Gly Asp Lys Gln Leu Ser Val Pro Glu Phe Ile Ser 
    210                 215                 220                 


Leu Pro Val Gly Thr Val Glu Asn Gln Gln Gly Gln Asp Ile Asp Asp 
225                 230                 235                 240 


Asn Trp Val Lys Asp Arg Lys Lys Glu Phe Glu Glu Leu Ile Asp Ser 
                245                 250                 255     


Asn His Asp Gly Ile Val Thr Ala Glu Glu Leu Glu Ser Tyr Met Asp 
            260                 265                 270         


Pro Met Asn Glu Tyr Asn Ala Leu Asn Glu Ala Lys Gln Met Ile Ala 
        275                 280                 285             


Val Ala Asp Glu Asn Gln Asn His His Leu Glu Pro Glu Glu Val Leu 
    290                 295                 300                 


Lys Tyr Ser Glu Phe Phe Thr Gly Ser Lys Leu Val Asp Tyr Ala Arg 
305                 310                 315                 320 


Ser Val His Glu Glu Phe 
                325     


<210>  2855
<211>  150
<212>  PRT
<213>  Homo Sapiens

<400>  2855

Gly Glu Gln Ser Gln Ala Leu Ala Gln Ser Ile Lys Asp Pro Gly Pro 
1               5                   10                  15      


Thr Arg Thr Phe Thr Val Val Pro Arg Ala Ala Glu Ser Thr Glu Ile 
            20                  25                  30          


Pro Pro Tyr Val Met Lys Cys Pro Ser Asn Gly Leu Cys Ser Arg Leu 
        35                  40                  45              


Pro Ala Asp Cys Ile Asp Cys Thr Thr Asn Phe Ser Cys Thr Tyr Gly 
    50                  55                  60                  


Lys Pro Val Thr Phe Asp Cys Ala Val Lys Pro Ser Val Thr Cys Val 
65                  70                  75                  80  


Asp Gln Asp Phe Lys Ser Gln Lys Asn Phe Ile Ile Asn Met Thr Cys 
                85                  90                  95      


Arg Phe Cys Trp Gln Leu Pro Glu Thr Asp Tyr Glu Cys Thr Asn Ser 
            100                 105                 110         


Thr Ser Cys Met Thr Val Ser Cys Pro Arg Gln Arg Tyr Pro Ala Asn 
        115                 120                 125             


Cys Thr Val Arg Asp His Val His Cys Leu Gly Asn Arg Thr Phe Pro 
    130                 135                 140                 


Lys Met Leu Tyr Cys Asn 
145                 150 


<210>  2856
<211>  475
<212>  PRT
<213>  Homo Sapiens

<400>  2856

Leu Glu Pro Glu Leu Pro Gly Ser Ala Leu Arg Ser Leu Trp Ser Ser 
1               5                   10                  15      


Leu Cys Leu Gly Pro Ala Pro Ala Pro Pro Gly Pro Val Ser Pro Glu 
            20                  25                  30          


Gly Arg Leu Ala Ala Ala Trp Asp Ala Leu Ile Val Arg Pro Val Arg 
        35                  40                  45              


Arg Trp Arg Arg Val Ala Val Gly Val Asn Ala Cys Val Asp Val Val 
    50                  55                  60                  


Leu Ser Gly Val Lys Leu Leu Gln Ala Leu Gly Leu Ser Pro Gly Asn 
65                  70                  75                  80  


Gly Lys Asp His Ser Ile Leu His Ser Arg Asn Asp Leu Glu Glu Ala 
                85                  90                  95      


Phe Ile His Phe Met Gly Lys Gly Ala Ala Ala Glu Arg Phe Phe Ser 
            100                 105                 110         


Asp Lys Glu Thr Phe His Asp Ile Ala Gln Val Ala Ser Glu Phe Pro 
        115                 120                 125             


Gly Ala Gln His Tyr Val Gly Gly Asn Ala Ala Leu Ile Gly Gln Lys 
    130                 135                 140                 


Phe Ala Ala Asn Ser Asp Leu Lys Val Leu Leu Cys Gly Pro Val Gly 
145                 150                 155                 160 


Pro Lys Leu His Glu Leu Leu Asp Asp Asn Val Phe Val Pro Pro Glu 
                165                 170                 175     


Ser Leu Gln Glu Val Asp Glu Phe His Leu Ile Leu Glu Tyr Gln Ala 
            180                 185                 190         


Gly Glu Glu Trp Gly Gln Leu Lys Ala Pro His Ala Asn Arg Phe Ile 
        195                 200                 205             


Phe Ser His Asp Leu Ser Asn Gly Ala Met Asn Met Leu Glu Val Phe 
    210                 215                 220                 


Val Ser Ser Leu Glu Glu Phe Gln Pro Asp Leu Val Val Leu Ser Gly 
225                 230                 235                 240 


Leu His Met Met Glu Gly Gln Ser Lys Glu Leu Gln Arg Lys Arg Leu 
                245                 250                 255     


Leu Glu Val Val Thr Ser Ile Ser Asp Ile Pro Thr Gly Ile Pro Val 
            260                 265                 270         


His Leu Glu Leu Ala Ser Met Thr Asn Arg Glu Leu Met Ser Ser Ile 
        275                 280                 285             


Val His Gln Gln Val Phe Pro Ala Val Thr Ser Leu Gly Leu Asn Glu 
    290                 295                 300                 


Gln Glu Leu Leu Phe Leu Thr Gln Ser Ala Ser Gly Pro His Ser Ser 
305                 310                 315                 320 


Leu Ser Ser Trp Asn Gly Val Pro Asp Val Gly Met Val Ser Asp Ile 
                325                 330                 335     


Leu Phe Trp Ile Leu Lys Glu His Gly Arg Ser Lys Ser Arg Ala Ser 
            340                 345                 350         


Asp Leu Thr Arg Ile His Phe His Thr Leu Val Tyr His Ile Leu Ala 
        355                 360                 365             


Thr Val Asp Gly His Trp Ala Asn Gln Leu Ala Ala Val Ala Ala Gly 
    370                 375                 380                 


Ala Arg Val Ala Gly Thr Gln Ala Cys Ala Thr Glu Thr Ile Asp Thr 
385                 390                 395                 400 


Ser Arg Val Ser Leu Arg Ala Pro Gln Glu Phe Met Thr Ser His Ser 
                405                 410                 415     


Glu Ala Gly Ser Arg Ile Val Leu Asn Pro Asn Lys Pro Val Val Glu 
            420                 425                 430         


Trp His Arg Glu Gly Ile Ser Phe His Phe Thr Pro Val Leu Val Cys 
        435                 440                 445             


Lys Asp Pro Ile Arg Thr Val Gly Leu Gly Asp Ala Ile Ser Ala Glu 
    450                 455                 460                 


Gly Leu Phe Tyr Ser Glu Val His Pro His Tyr 
465                 470                 475 


<210>  2857
<211>  377
<212>  PRT
<213>  Homo Sapiens

<400>  2857

Glu Ile Thr Ser Leu Asp Thr Glu Asn Ile Asp Glu Ile Leu Asn Asn 
1               5                   10                  15      


Ala Asp Val Ala Leu Val Asn Phe Tyr Ala Asp Trp Cys Arg Phe Ser 
            20                  25                  30          


Gln Met Leu His Pro Ile Phe Glu Glu Ala Ser Asp Val Ile Lys Glu 
        35                  40                  45              


Glu Phe Pro Asn Glu Asn Gln Val Val Phe Ala Arg Val Asp Cys Asp 
    50                  55                  60                  


Gln His Ser Asp Ile Ala Gln Arg Tyr Arg Ile Ser Lys Tyr Pro Thr 
65                  70                  75                  80  


Leu Lys Leu Phe Arg Asn Gly Met Met Met Lys Arg Glu Tyr Arg Gly 
                85                  90                  95      


Gln Arg Ser Val Lys Ala Leu Ala Asp Tyr Ile Arg Gln Gln Lys Ser 
            100                 105                 110         


Asp Pro Ile Gln Glu Ile Arg Asp Leu Ala Glu Ile Thr Thr Leu Asp 
        115                 120                 125             


Arg Ser Lys Arg Asn Ile Ile Gly Tyr Phe Glu Gln Lys Asp Ser Asp 
    130                 135                 140                 


Asn Tyr Arg Val Phe Glu Arg Val Ala Asn Ile Leu His Asp Asp Cys 
145                 150                 155                 160 


Ala Phe Leu Ser Ala Phe Gly Asp Val Ser Lys Pro Glu Arg Tyr Ser 
                165                 170                 175     


Gly Asp Asn Ile Ile Tyr Lys Pro Pro Gly His Ser Ala Pro Asp Met 
            180                 185                 190         


Val Tyr Leu Gly Ala Met Thr Asn Phe Asp Val Thr Tyr Asn Trp Ile 
        195                 200                 205             


Gln Asp Lys Cys Val Pro Leu Val Arg Glu Ile Thr Phe Glu Asn Gly 
    210                 215                 220                 


Glu Glu Leu Thr Glu Glu Gly Leu Pro Phe Leu Ile Leu Phe His Met 
225                 230                 235                 240 


Lys Glu Asp Thr Glu Ser Leu Glu Ile Phe Gln Asn Glu Val Ala Arg 
                245                 250                 255     


Gln Leu Ile Ser Glu Lys Gly Thr Ile Asn Phe Leu His Ala Asp Cys 
            260                 265                 270         


Asp Lys Phe Arg His Pro Leu Leu His Ile Gln Lys Thr Pro Ala Asp 
        275                 280                 285             


Cys Pro Val Ile Ala Ile Asp Ser Phe Arg His Met Tyr Val Phe Gly 
    290                 295                 300                 


Asp Phe Lys Asp Val Leu Ile Pro Gly Lys Leu Lys Gln Phe Val Phe 
305                 310                 315                 320 


Asp Leu His Ser Gly Lys Leu His Arg Glu Phe His His Gly Pro Asp 
                325                 330                 335     


Pro Thr Asp Thr Ala Pro Gly Glu Gln Ala Gln Asp Val Ala Ser Ser 
            340                 345                 350         


Pro Pro Glu Ser Ser Phe Gln Lys Leu Ala Pro Ser Glu Tyr Arg Tyr 
        355                 360                 365             


Thr Leu Leu Arg Asp Arg Asp Glu Leu 
    370                 375         


<210>  2858
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  2858

Ala Asp Gly Ser Ala Ala Val Ala Thr Ser Asp Phe Cys Val Ala Pro 
1               5                   10                  15      


Asp Thr Phe Ile Leu Asn Val Thr Glu Gly Gln Ile Ser Thr Glu Val 
            20                  25                  30          


Thr Arg Tyr Tyr Leu Tyr Cys Ser Gln Ser Gly Ser Ser Pro Phe Gln 
        35                  40                  45              


Gln Thr Leu Thr Thr Phe Gln Arg Ala Leu Thr Thr Met Gln Ile Gln 
    50                  55                  60                  


Val Ala Gly Leu Leu Gln Phe Ala Val Pro Leu Phe Ser Thr Ala Glu 
65                  70                  75                  80  


Glu Asp Leu Leu Ala Ile Gln Leu Leu Leu Asn Ser Ser Glu Ser Ser 
                85                  90                  95      


Leu His Gln Leu Thr Ala Met Val Asp Cys Arg Gly Leu His Lys Asp 
            100                 105                 110         


Tyr Leu Asp Ala Leu Ala Gly Ile Cys Tyr Asp Gly Leu Gln Gly 
        115                 120                 125         


<210>  2859
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  2859

His Gly Phe Arg Ile His Asp Tyr Leu Tyr Phe Gln Val Leu Ser Pro 
1               5                   10                  15      


Gly Asp Ile Arg Tyr Ile Phe Thr Ala Thr Pro Ala Lys Asp Phe Gly 
            20                  25                  30          


Gly Ile Phe His Thr Arg Tyr Glu Gln Ile His Leu Val Pro Ala Glu 
        35                  40                  45              


Pro Pro Glu Ala Cys Gly Glu Leu Ser Asn Gly Phe Phe Ile Gln Asp 
    50                  55                  60                  


Gln Ile Ala Leu Val Glu Arg Gly Gly Cys Ser Phe Leu Ser Lys Thr 
65                  70                  75                  80  


Arg Val Val Gln Glu His Gly Gly Arg Ala Val Ile Ile Ser Asp Asn 
                85                  90                  95      


Ala Val Asp Asn Asp Ser Phe Tyr Val Glu Met Ile Gln Asp Ser Thr 
            100                 105                 110         


Gln Arg Thr Ala Asp Ile Pro Ala Leu Phe Leu Leu Gly Arg Asp Gly 
        115                 120                 125             


Tyr Met Ile Arg Arg Ser Leu Glu Gln His Gly Leu Pro Trp Ala Ile 
    130                 135                 140                 


Ile Ser Ile Pro Val Asn Val Thr Ser Ile Pro Thr Phe Glu Leu Leu 
145                 150                 155                 160 


Gln Pro Pro Trp Thr Phe Trp 
                165         


<210>  2860
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  2860

Ser Arg Pro Leu Gln Ala Arg Ser Gln Gln His His Gly Leu Ala Ala 
1               5                   10                  15      


Asp Leu Gly Lys Gly Lys Leu His Leu Ala Gly Pro Cys Cys Pro Ser 
            20                  25                  30          


Glu Met Asp Thr Thr Glu Thr Ser Gly Pro Gly Asn His Pro Glu Arg 
        35                  40                  45              


Cys Gly Val Pro Ser Pro Glu Cys Glu Ser Phe Leu Glu His Leu Gln 
    50                  55                  60                  


Arg Ala Leu Arg Ser Arg Phe Arg Leu Arg Leu Leu Gly Val Arg Gln 
65                  70                  75                  80  


Ala Gln Pro Leu Cys Glu Glu Leu Cys Gln Ala Trp Phe Ala Asn Cys 
                85                  90                  95      


Glu Asp Asp Ile Thr Cys Gly Pro Thr Trp Leu Pro Leu Ser Glu Lys 
            100                 105                 110         


Arg Gly Cys Glu Pro Ser Cys Leu Thr Tyr Gly Gln Thr Phe Ala Asp 
        115                 120                 125             


Gly Thr Asp Leu Cys Arg Ser Ala Leu Gly His Ala Leu Pro Val Ala 
    130                 135                 140                 


Ala Pro Gly Ala Arg His Cys Phe Asn Ile Ser Ile Ser Ala Val Pro 
145                 150                 155                 160 


Arg Pro Arg Pro Gly Arg Arg Gly Arg Glu Ala Pro Ser Arg Arg Ser 
                165                 170                 175     


Arg Ser Pro Arg Thr Ser Ile Leu Asp Ala Ala Gly Ser Gly Ser Gly 
            180                 185                 190         


Ser Gly Ser Gly Ser Gly Pro 
        195                 


<210>  2861
<211>  552
<212>  PRT
<213>  Homo Sapiens

<400>  2861

Met Ser Asp Asn Pro Pro Arg Met Glu Val Cys Pro Tyr Cys Lys Lys 
1               5                   10                  15      


Pro Phe Lys Arg Leu Lys Ser His Leu Pro Tyr Cys Lys Met Ile Gly 
            20                  25                  30          


Pro Thr Ile Pro Thr Asp Gln Lys Val Tyr Gln Ser Lys Pro Ala Thr 
        35                  40                  45              


Leu Pro Arg Ala Lys Lys Met Lys Gly Pro Ile Lys Asp Leu Ile Lys 
    50                  55                  60                  


Ala Lys Gly Lys Glu Leu Glu Thr Glu Asn Glu Glu Arg Asn Ser Lys 
65                  70                  75                  80  


Leu Val Val Asp Lys Pro Glu Gln Thr Val Lys Thr Phe Pro Leu Pro 
                85                  90                  95      


Ala Val Gly Leu Glu Arg Ala Ala Thr Thr Lys Ala Asp Lys Asp Ile 
            100                 105                 110         


Lys Asn Pro Ile Gln Pro Ser Phe Lys Met Leu Lys Asn Thr Lys Pro 
        115                 120                 125             


Met Thr Thr Phe Gln Glu Glu Thr Lys Ala Gln Phe Tyr Ala Ser Glu 
    130                 135                 140                 


Lys Thr Ser Pro Lys Arg Glu Leu Ala Lys Asp Leu Pro Lys Ser Gly 
145                 150                 155                 160 


Glu Ser Arg Cys Asn Pro Ser Glu Ala Gly Ala Ser Leu Leu Val Gly 
                165                 170                 175     


Ser Ile Glu Pro Ser Leu Ser Asn Gln Asp Arg Lys Tyr Ser Ser Thr 
            180                 185                 190         


Leu Pro Asn Asp Val Gln Thr Thr Ser Gly Asp Leu Lys Leu Asp Lys 
        195                 200                 205             


Ile Asp Pro Gln Arg Gln Glu Leu Leu Val Lys Leu Leu Asp Val Pro 
    210                 215                 220                 


Thr Gly Asp Cys His Ile Ser Pro Lys Asn Val Ser Asp Gly Val Lys 
225                 230                 235                 240 


Arg Val Arg Thr Leu Leu Ser Asn Glu Arg Asp Ser Lys Gly Arg Asp 
                245                 250                 255     


His Leu Ser Gly Val Pro Thr Asp Val Thr Val Thr Glu Thr Pro Glu 
            260                 265                 270         


Lys Asn Thr Glu Ser Leu Ile Leu Ser Leu Lys Met Ser Ser Leu Gly 
        275                 280                 285             


Lys Ile Gln Val Met Glu Lys Gln Glu Lys Gly Leu Thr Leu Gly Val 
    290                 295                 300                 


Glu Thr Cys Gly Ser Lys Gly Asn Ala Glu Lys Ser Met Ser Ala Thr 
305                 310                 315                 320 


Glu Lys Gln Glu Arg Thr Val Met Ser His Gly Cys Glu Asn Phe Asn 
                325                 330                 335     


Thr Arg Asp Ser Val Thr Gly Lys Glu Ser Gln Gly Glu Arg Pro His 
            340                 345                 350         


Leu Ser Leu Phe Ile Pro Arg Glu Thr Thr Tyr Gln Phe His Ser Val 
        355                 360                 365             


Ser Gln Ser Ser Ser Gln Ser Leu Ala Ser Leu Ala Thr Thr Phe Leu 
    370                 375                 380                 


Gln Glu Lys Lys Ala Glu Ala Gln Asn His Asn Cys Val Pro Asp Val 
385                 390                 395                 400 


Lys Ala Leu Met Glu Ser Pro Glu Gly Gln Leu Ser Leu Glu Pro Lys 
                405                 410                 415     


Ser Asp Ser Gln Phe Gln Ala Ser His Thr Gly Cys Gln Ser Pro Leu 
            420                 425                 430         


Cys Ser Ala Gln Arg His Thr Pro Gln Ser Pro Phe Thr Asn His Ala 
        435                 440                 445             


Ala Ala Ala Gly Arg Lys Thr Leu Arg Ser Cys Met Gly Leu Glu Trp 
    450                 455                 460                 


Phe Pro Glu Leu Tyr Pro Gly Tyr Leu Gly Leu Gly Val Leu Pro Gly 
465                 470                 475                 480 


Lys Pro Gln Cys Trp Asn Ala Met Thr Gln Lys Pro Gln Leu Ile Ser 
                485                 490                 495     


Pro Gln Gly Glu Arg Leu Ser Gln Val Ser Leu Leu Glu Arg Ser Ser 
            500                 505                 510         


Thr His Ile Arg Ser Leu Glu Pro Pro Ala Gly Leu Thr Thr Ser Asn 
        515                 520                 525             


Phe Ser Leu Met Arg Leu Leu Gly Ala Val Gln Lys Gly Trp Ile Arg 
    530                 535                 540                 


Cys Asn Thr Thr Ile Arg Lys Ser 
545                 550         


<210>  2862
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  2862

Thr Ser Asn Trp Val Cys Gln Thr Leu Glu Asp Gly Arg Arg Arg Ser 
1               5                   10                  15      


Val Gly Leu Trp Arg Ser Cys Trp Leu Val Asp Arg Thr Arg Gly Gly 
            20                  25                  30          


Pro Ser Pro Gly Ala Arg Ala Gly Gln Val Asp Ala His Asp Cys Glu 
        35                  40                  45              


Ala Leu Gly Trp Gly Ser Glu Ala Ala Gly Phe Gln Glu Ser Arg Gly 
    50                  55                  60                  


Thr Val Lys Leu Gln Phe Asp Met Met Arg Ala Cys Asn 
65                  70                  75          


<210>  2863
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2863

Gly Pro Ser Gln Ala Gly Ala Glu Glu Asn Asp Trp Val Arg Leu Pro 
1               5                   10                  15      


Ser Lys Cys Glu Val Cys Lys Tyr Val Ala Val Glu Leu Lys Ser Ala 
            20                  25                  30          


Phe Glu Glu Thr Gly Lys Thr Lys Glu Val Ile Gly Thr Gly Tyr Gly 
        35                  40                  45              


Ile Leu Asp Gln Lys Ala Ser Gly Val Lys Tyr Thr Lys Ser Asp Leu 
    50                  55                  60                  


Arg Leu Ile Glu Val Thr Glu Thr Ile Cys Lys Arg Leu Leu Asp Tyr 
65                  70                  75                  80  


Ser Leu His Lys Glu Arg Thr Gly Ser Asn Arg Phe Ala Lys Gly Met 
                85                  90                  95      


Ser Glu Thr Phe Glu Thr Leu His Asn Leu Val His Lys Gly Val Lys 
            100                 105                 110         


Val Val Met Asp Ile Pro Tyr Glu Leu Trp Asn Glu Thr Ser Ala Glu 
        115                 120                 125             


Val Ala Asp Leu Lys Lys Gln Cys Asp Val Leu Val Glu Glu Phe Glu 
    130                 135                 140                 


Glu Val Ile Glu Asp Trp Tyr Arg Asn His Gln Glu Glu Asp Leu Thr 
145                 150                 155                 160 


Glu Phe Leu Cys Ala Asn His Val Leu Lys Gly Lys Asp Thr Ser Cys 
                165                 170                 175     


Leu Ala Glu Gln Trp Ser Gly Lys Lys Gly Asp Thr Ala Ala Leu Gly 
            180                 185                 190         


Gly Lys Lys Ser Lys Lys Lys Ser Ser Arg Ala Lys Ala Ala Gly Gly 
        195                 200                 205             


Arg Ser Ser Ser Ser Lys Gln Arg Lys Glu Leu Gly Gly Leu Glu Gly 
    210                 215                 220                 


Asp Pro Ser Pro Glu Glu Asp Glu Gly Ile Gln Lys Ala Ser Pro Leu 
225                 230                 235                 240 


Thr His Ser Pro Pro Asp Glu Leu 
                245             


<210>  2864
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  2864

Ala Pro Gln Arg Leu Leu Glu Arg Arg Asn Trp Thr Pro Gln Ala Met 
1               5                   10                  15      


Leu Tyr Leu Lys Gly Ala Gln Gly Arg Arg Phe Ile Ser Asp Gln Ser 
            20                  25                  30          


Arg Arg Lys Asp Leu Ser Asp Arg Pro Leu Pro Glu Arg Arg Ser Pro 
        35                  40                  45              


Asn Pro Gln Leu Leu Thr Ile Pro Glu Ala Ala Thr Ile Leu Leu Ala 
    50                  55                  60                  


Ser Leu Gln Lys Ser Pro Glu Asp Glu Glu Lys Asn Phe Asp Gln Thr 
65                  70                  75                  80  


Arg Phe Leu Glu Asp Ser Leu Leu Asn Trp 
                85                  90  


<210>  2865
<211>  439
<212>  PRT
<213>  Homo Sapiens

<400>  2865

His Ser Ala Thr Arg Phe Asp Pro Thr Trp Glu Ser Leu Asp Ala Arg 
1               5                   10                  15      


Gln Leu Pro Ala Trp Phe Asp Gln Ala Lys Phe Gly Ile Phe Ile His 
            20                  25                  30          


Trp Gly Val Phe Ser Val Pro Ser Phe Gly Ser Glu Trp Phe Trp Trp 
        35                  40                  45              


Tyr Trp Gln Lys Glu Lys Ile Pro Lys Tyr Val Glu Phe Met Lys Asp 
    50                  55                  60                  


Asn Tyr Pro Pro Ser Phe Lys Tyr Glu Asp Phe Gly Pro Leu Phe Thr 
65                  70                  75                  80  


Ala Lys Phe Phe Asn Ala Asn Gln Trp Ala Asp Ile Phe Gln Ala Ser 
                85                  90                  95      


Gly Ala Lys Tyr Ile Val Leu Thr Ser Lys His His Glu Gly Phe Thr 
            100                 105                 110         


Leu Trp Gly Ser Glu Tyr Ser Trp Asn Trp Asn Ala Ile Asp Glu Gly 
        115                 120                 125             


Pro Lys Arg Asp Ile Val Lys Glu Leu Glu Val Ala Ile Arg Asn Arg 
    130                 135                 140                 


Thr Asp Leu Arg Phe Gly Leu Tyr Tyr Ser Leu Phe Glu Trp Phe His 
145                 150                 155                 160 


Pro Leu Phe Leu Glu Asp Glu Ser Ser Ser Phe His Lys Arg Gln Phe 
                165                 170                 175     


Pro Val Ser Lys Thr Leu Pro Glu Leu Tyr Glu Leu Val Asn Asn Tyr 
            180                 185                 190         


Gln Pro Glu Val Leu Trp Ser Asp Gly Asp Gly Gly Ala Pro Asp Gln 
        195                 200                 205             


Tyr Trp Asn Ser Thr Gly Phe Leu Ala Trp Leu Tyr Asn Glu Ser Pro 
    210                 215                 220                 


Val Arg Gly Thr Val Val Thr Asn Asp Arg Trp Gly Ala Gly Ser Ile 
225                 230                 235                 240 


Cys Lys His Gly Gly Phe Tyr Thr Cys Ser Asp Arg Tyr Asn Pro Gly 
                245                 250                 255     


His Leu Leu Pro His Lys Trp Glu Asn Cys Met Thr Ile Asp Lys Leu 
            260                 265                 270         


Ser Trp Gly Tyr Arg Arg Glu Ala Gly Ile Ser Asp Tyr Leu Thr Ile 
        275                 280                 285             


Glu Glu Leu Val Lys Gln Leu Val Glu Thr Val Ser Cys Gly Gly Asn 
    290                 295                 300                 


Leu Leu Met Asn Ile Gly Pro Thr Leu Asp Gly Thr Ile Ser Val Val 
305                 310                 315                 320 


Phe Glu Glu Arg Leu Arg Gln Val Gly Ser Trp Leu Lys Val Asn Gly 
                325                 330                 335     


Glu Ala Ile Tyr Glu Thr Tyr Thr Trp Arg Ser Gln Asn Asp Thr Val 
            340                 345                 350         


Thr Pro Asp Val Trp Tyr Thr Ser Lys Pro Lys Glu Lys Leu Val Tyr 
        355                 360                 365             


Ala Ile Phe Leu Lys Trp Pro Thr Ser Gly Gln Leu Phe Leu Gly His 
    370                 375                 380                 


Pro Lys Ala Ile Leu Gly Ala Thr Glu Val Lys Leu Leu Gly His Gly 
385                 390                 395                 400 


Gln Pro Leu Asn Trp Ile Ser Leu Glu Gln Asn Gly Ile Met Val Glu 
                405                 410                 415     


Leu Pro Gln Leu Thr Ile His Gln Met Pro Cys Lys Trp Gly Trp Ala 
            420                 425                 430         


Leu Ala Leu Thr Asn Val Ile 
        435                 


<210>  2866
<211>  429
<212>  PRT
<213>  Homo Sapiens

<400>  2866

Glu Gln Val Lys His Ser Glu Thr Tyr Cys Met Phe Gln Asp Lys Lys 
1               5                   10                  15      


Tyr Arg Val Gly Glu Arg Trp His Pro Tyr Leu Glu Pro Tyr Gly Leu 
            20                  25                  30          


Val Tyr Cys Val Asn Cys Ile Cys Ser Glu Asn Gly Asn Val Leu Cys 
        35                  40                  45              


Ser Arg Val Arg Cys Pro Asn Val His Cys Leu Ser Pro Val His Ile 
    50                  55                  60                  


Pro His Leu Cys Cys Pro Arg Cys Pro Asp Ser Leu Pro Pro Val Asn 
65                  70                  75                  80  


Asn Lys Val Thr Ser Lys Ser Cys Glu Tyr Asn Gly Thr Thr Tyr Gln 
                85                  90                  95      


His Gly Glu Leu Phe Val Ala Glu Gly Leu Phe Gln Asn Arg Gln Pro 
            100                 105                 110         


Asn Gln Cys Thr Gln Cys Ser Cys Ser Glu Gly Asn Val Tyr Cys Gly 
        115                 120                 125             


Leu Lys Thr Cys Pro Lys Leu Thr Cys Ala Phe Pro Val Ser Val Pro 
    130                 135                 140                 


Asp Ser Cys Cys Arg Val Cys Arg Gly Asp Gly Glu Leu Ser Trp Glu 
145                 150                 155                 160 


His Ser Asp Gly Asp Ile Phe Arg Gln Pro Ala Asn Arg Glu Ala Arg 
                165                 170                 175     


His Ser Tyr His Arg Ser His Tyr Asp Pro Pro Pro Ser Arg Gln Ala 
            180                 185                 190         


Gly Gly Leu Ser Arg Phe Pro Gly Ala Arg Ser His Arg Gly Ala Leu 
        195                 200                 205             


Met Asp Ser Gln Gln Ala Ser Gly Thr Ile Val Gln Ile Val Ile Asn 
    210                 215                 220                 


Asn Lys His Lys His Gly Gln Val Cys Val Ser Asn Gly Lys Thr Tyr 
225                 230                 235                 240 


Ser His Gly Glu Ser Trp His Pro Asn Leu Arg Ala Phe Gly Ile Val 
                245                 250                 255     


Glu Cys Val Leu Cys Thr Cys Asn Val Thr Lys Gln Glu Cys Lys Lys 
            260                 265                 270         


Ile His Cys Pro Asn Arg Tyr Pro Cys Lys Tyr Pro Gln Lys Ile Asp 
        275                 280                 285             


Gly Lys Cys Cys Lys Val Cys Pro Gly Lys Lys Ala Lys Glu Leu Pro 
    290                 295                 300                 


Gly Gln Ser Phe Asp Asn Lys Gly Tyr Phe Cys Gly Glu Glu Thr Met 
305                 310                 315                 320 


Pro Val Tyr Glu Ser Val Phe Met Glu Asp Gly Glu Thr Thr Arg Lys 
                325                 330                 335     


Ile Ala Leu Glu Thr Glu Arg Pro Pro Gln Val Glu Val His Val Trp 
            340                 345                 350         


Thr Ile Arg Lys Gly Ile Leu Gln His Phe His Ile Glu Lys Ile Ser 
        355                 360                 365             


Lys Arg Met Phe Glu Glu Leu Pro His Phe Lys Leu Val Thr Arg Thr 
    370                 375                 380                 


Thr Leu Ser Gln Trp Lys Ile Phe Thr Glu Gly Glu Ala Gln Ile Ser 
385                 390                 395                 400 


Gln Met Cys Ser Ser Arg Val Cys Arg Thr Glu Leu Glu Asp Leu Val 
                405                 410                 415     


Lys Val Leu Tyr Leu Glu Arg Ser Glu Lys Gly His Cys 
            420                 425                 


<210>  2867
<211>  82
<212>  PRT
<213>  Homo Sapiens

<400>  2867

Lys Lys Asp Ser Pro Pro Lys Asn Ser Val Lys Val Asp Glu Leu Ser 
1               5                   10                  15      


Leu Tyr Ser Val Pro Glu Gly Gln Ser Lys Tyr Val Glu Glu Ala Arg 
            20                  25                  30          


Ser Gln Leu Glu Glu Ser Ile Ser Gln Leu Arg His Tyr Cys Glu Pro 
        35                  40                  45              


Tyr Thr Thr Trp Cys Gln Glu Thr Tyr Ser Gln Thr Lys Pro Lys Met 
    50                  55                  60                  


Gln Ser Leu Val Gln Trp Gly Leu Asp Ser Tyr Asp Tyr Leu Gln Asn 
65                  70                  75                  80  


Ala Pro 
        


<210>  2868
<211>  557
<212>  PRT
<213>  Homo Sapiens

<400>  2868

Ala Pro Gly Pro Asp Gly Ser Ala Pro Asp Pro Ala His Tyr Arg Glu 
1               5                   10                  15      


Arg Val Lys Ala Met Phe Tyr His Ala Tyr Asp Ser Tyr Leu Glu Asn 
            20                  25                  30          


Ala Phe Pro Phe Asp Glu Leu Arg Pro Leu Thr Cys Asp Gly His Asp 
        35                  40                  45              


Thr Trp Gly Ser Phe Ser Leu Thr Leu Ile Asp Ala Leu Asp Thr Leu 
    50                  55                  60                  


Leu Ile Leu Gly Asn Val Ser Glu Phe Gln Arg Val Val Glu Val Leu 
65                  70                  75                  80  


Gln Asp Ser Val Asp Phe Asp Ile Asp Val Asn Ala Ser Val Phe Glu 
                85                  90                  95      


Thr Asn Ile Arg Val Val Gly Gly Leu Leu Ser Ala His Leu Leu Ser 
            100                 105                 110         


Lys Lys Ala Gly Val Glu Val Glu Ala Gly Trp Pro Cys Ser Gly Pro 
        115                 120                 125             


Leu Leu Arg Met Ala Glu Glu Ala Ala Arg Lys Leu Leu Pro Ala Phe 
    130                 135                 140                 


Gln Thr Pro Thr Gly Met Pro Tyr Gly Thr Val Asn Leu Leu His Gly 
145                 150                 155                 160 


Val Asn Pro Gly Glu Thr Pro Val Thr Cys Thr Ala Gly Ile Gly Thr 
                165                 170                 175     


Phe Ile Val Glu Phe Ala Thr Leu Ser Ser Leu Thr Gly Asp Pro Val 
            180                 185                 190         


Phe Glu Asp Val Ala Arg Val Ala Leu Met Arg Leu Trp Glu Ser Arg 
        195                 200                 205             


Ser Asp Ile Gly Leu Val Gly Asn His Ile Asp Val Leu Thr Gly Lys 
    210                 215                 220                 


Trp Val Ala Gln Asp Ala Gly Ile Gly Ala Gly Val Asp Ser Tyr Phe 
225                 230                 235                 240 


Glu Tyr Leu Val Lys Gly Ala Ile Leu Leu Gln Asp Lys Lys Leu Met 
                245                 250                 255     


Ala Met Phe Leu Glu Tyr Asn Lys Ala Ile Arg Asn Tyr Thr Arg Phe 
            260                 265                 270         


Asp Asp Trp Tyr Leu Trp Val Gln Met Tyr Lys Gly Thr Val Ser Met 
        275                 280                 285             


Pro Val Phe Gln Ser Leu Glu Ala Tyr Trp Pro Gly Leu Gln Ser Leu 
    290                 295                 300                 


Ile Gly Asp Ile Asp Asn Ala Met Arg Thr Phe Leu Asn Tyr Tyr Thr 
305                 310                 315                 320 


Val Trp Lys Gln Phe Gly Gly Leu Pro Glu Phe Tyr Asn Ile Pro Gln 
                325                 330                 335     


Gly Tyr Thr Val Glu Lys Arg Glu Gly Tyr Pro Leu Arg Pro Glu Leu 
            340                 345                 350         


Ile Glu Ser Ala Met Tyr Leu Tyr Arg Ala Thr Gly Asp Pro Thr Leu 
        355                 360                 365             


Leu Glu Leu Gly Arg Asp Ala Val Glu Ser Ile Glu Lys Ile Ser Lys 
    370                 375                 380                 


Val Glu Cys Gly Phe Ala Thr Ile Lys Asp Leu Arg Asp His Lys Leu 
385                 390                 395                 400 


Asp Asn Arg Met Glu Ser Phe Phe Leu Ala Glu Thr Val Lys Tyr Leu 
                405                 410                 415     


Tyr Leu Leu Phe Asp Pro Thr Asn Phe Ile His Asn Asn Gly Ser Thr 
            420                 425                 430         


Phe Asp Thr Val Ile Thr Pro Tyr Gly Glu Cys Ile Leu Gly Ala Gly 
        435                 440                 445             


Gly Tyr Ile Phe Asn Thr Glu Ala His Pro Ile Asp Pro Ala Ala Leu 
    450                 455                 460                 


His Cys Cys Gln Arg Leu Lys Glu Glu Gln Trp Glu Val Glu Asp Leu 
465                 470                 475                 480 


Met Arg Glu Phe Tyr Ser Leu Lys Arg Ser Arg Ser Lys Phe Gln Lys 
                485                 490                 495     


Asn Thr Val Ser Ser Gly Pro Trp Glu Pro Pro Ala Arg Pro Gly Thr 
            500                 505                 510         


Leu Phe Ser Pro Glu Asn His Asp Gln Ala Arg Glu Arg Lys Pro Ala 
        515                 520                 525             


Lys Gln Lys Val Pro Leu Leu Ser Cys Pro Ser Gln Pro Phe Thr Ser 
    530                 535                 540                 


Lys Leu Ala Leu Leu Gly Gln Val Phe Leu Asp Ser Ser 
545                 550                 555         


<210>  2869
<211>  374
<212>  PRT
<213>  Homo Sapiens

<400>  2869

Thr Leu Ser Lys Ser Asp Ala Lys Lys Ala Ala Ser Lys Thr Leu Leu 
1               5                   10                  15      


Glu Lys Ser Gln Phe Ser Asp Lys Pro Val Gln Asp Arg Gly Leu Val 
            20                  25                  30          


Val Thr Asp Leu Lys Ala Glu Ser Val Val Leu Glu His Arg Ser Tyr 
        35                  40                  45              


Cys Ser Ala Lys Ala Arg Asp Arg His Phe Ala Gly Asp Val Leu Gly 
    50                  55                  60                  


Tyr Val Thr Pro Trp Asn Ser His Gly Tyr Asp Val Thr Lys Val Phe 
65                  70                  75                  80  


Gly Ser Lys Phe Thr Gln Ile Ser Pro Val Trp Leu Gln Leu Lys Arg 
                85                  90                  95      


Arg Gly Arg Glu Met Phe Glu Val Thr Gly Leu His Asp Val Asp Gln 
            100                 105                 110         


Gly Trp Met Arg Ala Val Arg Lys His Ala Lys Gly Leu His Ile Val 
        115                 120                 125             


Pro Arg Leu Leu Phe Glu Asp Trp Thr Tyr Asp Asp Phe Arg Asn Val 
    130                 135                 140                 


Leu Asp Ser Glu Asp Glu Ile Glu Glu Leu Ser Lys Thr Val Val Gln 
145                 150                 155                 160 


Val Ala Lys Asn Gln His Phe Asp Gly Phe Val Val Glu Val Trp Asn 
                165                 170                 175     


Gln Leu Leu Ser Gln Lys Arg Val Gly Leu Ile His Met Leu Thr His 
            180                 185                 190         


Leu Ala Glu Ala Leu His Gln Ala Arg Leu Leu Ala Leu Leu Val Ile 
        195                 200                 205             


Pro Pro Ala Ile Thr Pro Gly Thr Asp Gln Leu Gly Met Phe Thr His 
    210                 215                 220                 


Lys Glu Phe Glu Gln Leu Ala Pro Val Leu Asp Gly Phe Ser Leu Met 
225                 230                 235                 240 


Thr Tyr Asp Tyr Ser Thr Ala His Gln Pro Gly Pro Asn Ala Pro Leu 
                245                 250                 255     


Ser Trp Val Arg Ala Cys Val Gln Val Leu Asp Pro Lys Ser Lys Trp 
            260                 265                 270         


Arg Ser Lys Ile Leu Leu Gly Leu Asn Phe Tyr Gly Met Asp Tyr Ala 
        275                 280                 285             


Thr Ser Lys Asp Ala Arg Glu Pro Val Val Gly Ala Arg Tyr Ile Gln 
    290                 295                 300                 


Thr Leu Lys Asp His Arg Pro Arg Met Val Trp Asp Ser Gln Ala Ser 
305                 310                 315                 320 


Glu His Phe Phe Glu Tyr Lys Lys Ser Arg Ser Gly Arg His Val Val 
                325                 330                 335     


Phe Tyr Pro Thr Leu Lys Ser Leu Gln Val Arg Leu Glu Leu Ala Arg 
            340                 345                 350         


Glu Leu Gly Val Gly Val Ser Ile Trp Glu Leu Gly Gln Gly Leu Asp 
        355                 360                 365             


Tyr Phe Tyr Asp Leu Leu 
    370                 


<210>  2870
<211>  109
<212>  PRT
<213>  Homo Sapiens

<400>  2870

Gln Asn Ala Thr Ala Glu Pro Glu Leu Thr Ser Ala Gly Ala Ala Gln 
1               5                   10                  15      


Pro Glu Gly Pro Gly Gly Ala Ala Ser Trp Glu Tyr Gly Asp Pro His 
            20                  25                  30          


Ser Pro Val Ile Leu Cys Ser Tyr Leu Pro Asp Glu Phe Ile Glu Cys 
        35                  40                  45              


Glu Asp Pro Val Asp His Val Gly Asn Ala Thr Ala Ser Gln Glu Leu 
    50                  55                  60                  


Gly Tyr Gly Cys Leu Lys Phe Gly Gly Gln Ala Tyr Ser Asp Val Glu 
65                  70                  75                  80  


His Thr Ser Val Gln Cys His Ala Leu Asp Gly Ile Glu Cys Ala Ser 
                85                  90                  95      


Pro Arg Thr Phe Leu Arg Glu Asn Lys Pro Cys Ile Lys 
            100                 105                 


<210>  2871
<211>  81
<212>  PRT
<213>  Homo Sapiens

<400>  2871

Thr Ser Ala Gly Gly Glu Glu Ser Leu Lys Cys Glu Asp Leu Lys Val 
1               5                   10                  15      


Gly Gln Tyr Ile Cys Lys Asp Pro Lys Ile Asn Asp Ala Thr Gln Glu 
            20                  25                  30          


Pro Val Asn Cys Thr Asn Tyr Thr Ala His Val Ser Cys Phe Pro Ala 
        35                  40                  45              


Pro Asn Ile Thr Cys Lys Asp Ser Ser Gly Asn Glu Thr His Phe Thr 
    50                  55                  60                  


Gly Asn Glu Val Gly Phe Phe Lys Pro Ile Ser Cys Arg Asn Val Asn 
65                  70                  75                  80  


Gly 
    


<210>  2872
<211>  176
<212>  PRT
<213>  Homo Sapiens

<400>  2872

Gln Ser Asp Thr Ser Pro Asp Thr Glu Glu Ser Tyr Ser Asp Trp Gly 
1               5                   10                  15      


Leu Arg His Leu Arg Gly Ser Phe Glu Ser Val Asn Ser Tyr Phe Asp 
            20                  25                  30          


Ser Phe Leu Glu Leu Leu Gly Gly Lys Asn Gly Val Cys Gln Tyr Arg 
        35                  40                  45              


Cys Arg Tyr Gly Lys Ala Pro Met Pro Arg Pro Gly Tyr Lys Pro Gln 
    50                  55                  60                  


Glu Pro Asn Gly Cys Gly Ser Tyr Phe Leu Gly Leu Lys Val Pro Glu 
65                  70                  75                  80  


Ser Met Asp Leu Gly Ile Pro Ala Met Thr Lys Cys Cys Asn Gln Leu 
                85                  90                  95      


Asp Val Cys Tyr Asp Thr Cys Gly Ala Asn Lys Tyr Arg Cys Asp Ala 
            100                 105                 110         


Lys Phe Arg Trp Cys Leu His Ser Ile Cys Ser Asp Leu Lys Arg Ser 
        115                 120                 125             


Leu Gly Phe Val Ser Lys Val Glu Ala Ala Cys Asp Ser Leu Val Asp 
    130                 135                 140                 


Thr Val Phe Asn Thr Val Trp Thr Leu Gly Cys Arg Pro Phe Met Asn 
145                 150                 155                 160 


Ser Gln Arg Ala Ala Cys Ile Cys Ala Glu Glu Glu Lys Glu Glu Leu 
                165                 170                 175     


<210>  2873
<211>  394
<212>  PRT
<213>  Homo Sapiens

<400>  2873

Tyr Gly Asn Val His Val Ser Thr Glu Ser Asn Leu Gln Ala Thr Glu 
1               5                   10                  15      


Arg Arg Ala Glu Gly Leu Tyr Ser Gln Leu Leu Gly Leu Thr Ala Ser 
            20                  25                  30          


Gln Ser Asn Leu Thr Lys Glu Leu Asn Phe Thr Thr Arg Ala Lys Asp 
        35                  40                  45              


Ala Ile Met Gln Met Trp Leu Asn Ala Arg Arg Asp Leu Asp Arg Ile 
    50                  55                  60                  


Asn Ala Ser Phe Arg Gln Cys Gln Gly Asp Arg Val Ile Tyr Thr Asn 
65                  70                  75                  80  


Asn Gln Arg Tyr Met Ala Ala Ile Ile Leu Ser Glu Lys Gln Cys Arg 
                85                  90                  95      


Asp Gln Phe Lys Asp Met Asn Lys Ser Cys Asp Ala Leu Leu Phe Met 
            100                 105                 110         


Leu Asn Gln Lys Val Lys Thr Leu Glu Val Glu Ile Ala Lys Glu Lys 
        115                 120                 125             


Thr Ile Cys Thr Lys Asp Lys Glu Ser Val Leu Leu Asn Lys Arg Val 
    130                 135                 140                 


Ala Glu Glu Gln Leu Val Glu Cys Val Lys Thr Arg Glu Leu Gln His 
145                 150                 155                 160 


Gln Glu Arg Gln Leu Ala Lys Glu Gln Leu Gln Lys Val Gln Ala Leu 
                165                 170                 175     


Cys Leu Pro Leu Asp Lys Asp Lys Phe Glu Met Asp Leu Arg Asn Leu 
            180                 185                 190         


Trp Arg Asp Ser Ile Ile Pro Arg Ser Leu Asp Asn Leu Gly Tyr Asn 
        195                 200                 205             


Leu Tyr His Pro Leu Gly Ser Glu Leu Ala Ser Ile Arg Arg Ala Cys 
    210                 215                 220                 


Asp His Met Pro Ser Leu Met Ser Ser Lys Val Glu Glu Leu Ala Arg 
225                 230                 235                 240 


Ser Leu Arg Ala Asp Ile Glu Arg Val Ala Arg Glu Asn Ser Asp Leu 
                245                 250                 255     


Gln Arg Gln Lys Leu Glu Ala Gln Gln Gly Leu Arg Ala Ser Gln Glu 
            260                 265                 270         


Ala Lys Gln Lys Val Glu Lys Glu Ala Gln Ala Arg Glu Ala Lys Leu 
        275                 280                 285             


Gln Ala Glu Cys Ser Arg Gln Thr Gln Leu Ala Leu Glu Glu Lys Ala 
    290                 295                 300                 


Val Leu Arg Lys Glu Arg Asp Asn Leu Ala Lys Glu Leu Glu Glu Lys 
305                 310                 315                 320 


Lys Arg Glu Ala Glu Gln Leu Arg Met Glu Leu Ala Ile Arg Asn Ser 
                325                 330                 335     


Ala Leu Asp Thr Cys Ile Lys Thr Lys Ser Gln Pro Met Met Pro Val 
            340                 345                 350         


Ser Arg Pro Met Gly Pro Val Pro Asn Pro Gln Pro Ile Asp Pro Ala 
        355                 360                 365             


Ser Leu Glu Glu Phe Lys Arg Lys Ile Leu Glu Ser Gln Arg Pro Pro 
    370                 375                 380                 


Ala Gly Ile Pro Val Ala Pro Ser Ser Gly 
385                 390                 


<210>  2874
<211>  232
<212>  PRT
<213>  Homo Sapiens

<400>  2874

Thr Phe Asp Arg Ala Val Ala Ser Gly Cys Gln Arg Cys Cys Asp Ser 
1               5                   10                  15      


Glu Asp Pro Leu Asp Pro Ala His Val Ser Ser Ala Ser Ser Ser Gly 
            20                  25                  30          


Arg Pro His Ala Leu Pro Glu Ile Arg Pro Tyr Ile Asn Ile Thr Ile 
        35                  40                  45              


Leu Lys Gly Asp Lys Gly Asp Pro Gly Pro Met Gly Leu Pro Gly Tyr 
    50                  55                  60                  


Met Gly Arg Glu Gly Pro Gln Gly Glu Pro Gly Pro Gln Gly Ser Lys 
65                  70                  75                  80  


Gly Asp Lys Gly Glu Met Gly Ser Pro Gly Ala Pro Cys Gln Lys Arg 
                85                  90                  95      


Phe Phe Ala Phe Ser Val Gly Arg Lys Thr Ala Leu His Ser Gly Glu 
            100                 105                 110         


Asp Phe Gln Thr Leu Leu Phe Glu Arg Val Phe Val Asn Leu Asp Gly 
        115                 120                 125             


Cys Phe Asp Met Ala Thr Gly Gln Phe Ala Ala Pro Leu Arg Gly Ile 
    130                 135                 140                 


Tyr Phe Phe Ser Leu Asn Val His Ser Trp Asn Tyr Lys Glu Thr Tyr 
145                 150                 155                 160 


Val His Ile Met His Asn Gln Lys Glu Ala Val Ile Leu Tyr Ala Gln 
                165                 170                 175     


Pro Ser Glu Arg Ser Ile Met Gln Ser Gln Ser Val Met Leu Asp Leu 
            180                 185                 190         


Ala Tyr Gly Asp Arg Val Trp Val Arg Leu Phe Lys Arg Gln Arg Glu 
        195                 200                 205             


Asn Ala Ile Tyr Ser Asn Asp Phe Asp Thr Tyr Ile Thr Phe Ser Gly 
    210                 215                 220                 


His Leu Ile Lys Ala Glu Asp Asp 
225                 230         


<210>  2875
<211>  256
<212>  PRT
<213>  Homo Sapiens

<400>  2875

Arg Val Pro His Val Gln Gly Glu Gln Gln Glu Trp Glu Gly Thr Glu 
1               5                   10                  15      


Glu Leu Pro Ser Pro Pro Asp His Ala Glu Arg Ala Glu Glu Gln His 
            20                  25                  30          


Glu Lys Tyr Arg Pro Ser Gln Asp Gln Gly Leu Pro Ala Ser Arg Cys 
        35                  40                  45              


Leu Arg Cys Cys Asp Pro Gly Thr Ser Met Tyr Pro Ala Thr Ala Val 
    50                  55                  60                  


Pro Gln Ile Asn Ile Thr Ile Leu Lys Gly Glu Lys Gly Asp Arg Gly 
65                  70                  75                  80  


Asp Arg Gly Leu Gln Gly Lys Tyr Gly Lys Thr Gly Ser Ala Gly Ala 
                85                  90                  95      


Arg Gly His Thr Gly Pro Lys Gly Gln Lys Gly Ser Met Gly Ala Pro 
            100                 105                 110         


Gly Glu Arg Cys Lys Ser His Tyr Ala Ala Phe Ser Val Gly Arg Lys 
        115                 120                 125             


Lys Pro Met His Ser Asn His Tyr Tyr Gln Thr Val Ile Phe Asp Thr 
    130                 135                 140                 


Glu Phe Val Asn Leu Tyr Asp His Phe Asn Met Phe Thr Gly Lys Phe 
145                 150                 155                 160 


Tyr Cys Tyr Val Pro Gly Leu Tyr Phe Phe Ser Leu Asn Val His Thr 
                165                 170                 175     


Trp Asn Gln Lys Glu Thr Tyr Leu His Ile Met Lys Asn Glu Glu Glu 
            180                 185                 190         


Val Val Ile Leu Phe Ala Gln Val Gly Asp Arg Ser Ile Met Gln Ser 
        195                 200                 205             


Gln Ser Leu Met Leu Glu Leu Arg Glu Gln Asp Gln Val Trp Val Arg 
    210                 215                 220                 


Leu Tyr Lys Gly Glu Arg Glu Asn Ala Ile Phe Ser Glu Glu Leu Asp 
225                 230                 235                 240 


Thr Tyr Ile Thr Phe Ser Gly Tyr Leu Val Lys His Ala Thr Glu Pro 
                245                 250                 255     


<210>  2876
<211>  273
<212>  PRT
<213>  Homo Sapiens

<400>  2876

Gln Pro Arg Gly Asn Gln Leu Lys Gly Glu Asn Tyr Ser Pro Arg Tyr 
1               5                   10                  15      


Ile Cys Ser Ile Pro Gly Leu Pro Gly Pro Pro Gly Pro Pro Gly Ala 
            20                  25                  30          


Asn Gly Ser Pro Gly Pro His Gly Arg Ile Gly Leu Pro Gly Arg Asp 
        35                  40                  45              


Gly Arg Asp Gly Arg Lys Gly Glu Lys Gly Glu Lys Gly Thr Ala Gly 
    50                  55                  60                  


Leu Arg Gly Lys Thr Gly Pro Leu Gly Leu Ala Gly Glu Lys Gly Asp 
65                  70                  75                  80  


Gln Gly Glu Thr Gly Lys Lys Gly Pro Ile Gly Pro Glu Gly Glu Lys 
                85                  90                  95      


Gly Glu Val Gly Pro Ile Gly Pro Pro Gly Pro Lys Gly Asp Arg Gly 
            100                 105                 110         


Glu Gln Gly Asp Pro Gly Leu Pro Gly Val Cys Arg Cys Gly Ser Ile 
        115                 120                 125             


Val Leu Lys Ser Ala Phe Ser Val Gly Ile Thr Thr Ser Tyr Pro Glu 
    130                 135                 140                 


Glu Arg Leu Pro Ile Ile Phe Asn Lys Val Leu Phe Asn Glu Gly Glu 
145                 150                 155                 160 


His Tyr Asn Pro Ala Thr Gly Lys Phe Ile Cys Ala Phe Pro Gly Ile 
                165                 170                 175     


Tyr Tyr Phe Ser Tyr Asp Ile Thr Leu Ala Asn Lys His Leu Ala Ile 
            180                 185                 190         


Gly Leu Val His Asn Gly Gln Tyr Arg Ile Lys Thr Phe Asp Ala Asn 
        195                 200                 205             


Thr Gly Asn His Asp Val Ala Ser Gly Ser Thr Val Ile Tyr Leu Gln 
    210                 215                 220                 


Pro Glu Asp Glu Val Trp Leu Glu Ile Phe Phe Thr Asp Gln Asn Gly 
225                 230                 235                 240 


Leu Phe Ser Asp Pro Gly Trp Ala Asp Ser Leu Phe Ser Gly Phe Leu 
                245                 250                 255     


Leu Tyr Val Asp Thr Asp Tyr Leu Asp Ser Ile Ser Glu Asp Asp Glu 
            260                 265                 270         


Leu 
    


<210>  2877
<211>  297
<212>  PRT
<213>  Homo Sapiens

<400>  2877

Gln Asp Glu Tyr Met Glu Val Ser Gly Arg Thr Asn Lys Val Val Ala 
1               5                   10                  15      


Arg Ile Val Gln Ser His Gln Gln Thr Gly Arg Ser Gly Ser Arg Arg 
            20                  25                  30          


Glu Lys Val Arg Glu Arg Ser His Pro Lys Thr Gly Thr Val Asp Asn 
        35                  40                  45              


Asn Thr Ser Thr Asp Leu Lys Ser Leu Arg Pro Asp Glu Leu Pro His 
    50                  55                  60                  


Pro Glu Val Asp Asp Leu Ala Gln Ile Thr Thr Phe Trp Gly Gln Ser 
65                  70                  75                  80  


Pro Gln Thr Gly Gly Leu Pro Pro Asp Cys Ser Lys Cys Cys His Gly 
                85                  90                  95      


Asp Tyr Ser Phe Arg Gly Tyr Gln Gly Pro Pro Gly Pro Pro Gly Pro 
            100                 105                 110         


Pro Gly Ile Pro Gly Asn His Gly Asn Asn Gly Asn Asn Gly Ala Thr 
        115                 120                 125             


Gly His Glu Gly Ala Lys Gly Glu Lys Gly Asp Lys Gly Asp Leu Gly 
    130                 135                 140                 


Pro Arg Gly Glu Arg Gly Gln His Gly Pro Lys Gly Glu Lys Gly Tyr 
145                 150                 155                 160 


Pro Gly Ile Pro Pro Glu Leu Gln Ile Ala Phe Met Ala Ser Leu Ala 
                165                 170                 175     


Thr His Phe Ser Asn Gln Asn Ser Gly Ile Ile Phe Ser Ser Val Glu 
            180                 185                 190         


Thr Asn Ile Gly Asn Phe Phe Asp Val Met Thr Gly Arg Phe Gly Ala 
        195                 200                 205             


Pro Val Ser Gly Val Tyr Phe Phe Thr Phe Ser Met Met Lys His Glu 
    210                 215                 220                 


Asp Val Glu Glu Val Tyr Val Tyr Leu Met His Asn Gly Asn Thr Val 
225                 230                 235                 240 


Phe Ser Met Tyr Ser Tyr Glu Met Lys Gly Lys Ser Asp Thr Ser Ser 
                245                 250                 255     


Asn His Ala Val Leu Lys Leu Ala Lys Gly Asp Glu Val Trp Leu Arg 
            260                 265                 270         


Met Gly Asn Gly Ala Leu His Gly Asp His Gln Arg Phe Ser Thr Phe 
        275                 280                 285             


Ala Gly Phe Leu Leu Phe Glu Thr Lys 
    290                 295         


<210>  2878
<211>  551
<212>  PRT
<213>  Homo Sapiens

<400>  2878

Glu Gly Thr Leu Cys Asp Phe Pro Lys Ile His His Gly Phe Leu Tyr 
1               5                   10                  15      


Asp Glu Glu Asp Tyr Asn Pro Phe Ser Gln Val Pro Thr Gly Glu Val 
            20                  25                  30          


Phe Tyr Tyr Ser Cys Glu Tyr Asn Phe Val Ser Pro Ser Lys Ser Phe 
        35                  40                  45              


Trp Thr Arg Ile Thr Cys Thr Glu Glu Gly Trp Ser Pro Thr Pro Lys 
    50                  55                  60                  


Cys Leu Arg Met Cys Ser Phe Pro Phe Val Lys Asn Gly His Ser Glu 
65                  70                  75                  80  


Ser Ser Gly Leu Ile His Leu Glu Gly Asp Thr Val Gln Ile Ile Cys 
                85                  90                  95      


Asn Thr Gly Tyr Ser Leu Gln Asn Asn Glu Lys Asn Ile Ser Cys Val 
            100                 105                 110         


Glu Arg Gly Trp Ser Thr Pro Pro Ile Cys Ser Phe Thr Lys Gly Glu 
        115                 120                 125             


Cys His Val Pro Ile Leu Glu Ala Asn Val Asp Ala Gln Pro Lys Lys 
    130                 135                 140                 


Glu Ser Tyr Lys Val Gly Asp Val Leu Lys Phe Ser Cys Arg Lys Asn 
145                 150                 155                 160 


Leu Ile Arg Val Gly Ser Asp Ser Val Gln Cys Tyr Gln Phe Gly Trp 
                165                 170                 175     


Ser Pro Asn Phe Pro Thr Cys Lys Gly Gln Val Arg Ser Cys Gly Pro 
            180                 185                 190         


Pro Pro Gln Leu Ser Asn Gly Glu Val Lys Glu Ile Arg Lys Glu Glu 
        195                 200                 205             


Tyr Gly His Asn Glu Val Val Glu Tyr Asp Cys Asn Pro Asn Phe Ile 
    210                 215                 220                 


Ile Asn Gly Pro Lys Lys Ile Gln Cys Val Asp Gly Glu Trp Thr Thr 
225                 230                 235                 240 


Leu Pro Thr Cys Val Glu Gln Val Lys Thr Cys Gly Tyr Ile Pro Glu 
                245                 250                 255     


Leu Glu Tyr Gly Tyr Val Gln Pro Ser Val Pro Pro Tyr Gln His Gly 
            260                 265                 270         


Val Ser Val Glu Val Asn Cys Arg Asn Glu Tyr Ala Met Ile Gly Asn 
        275                 280                 285             


Asn Met Ile Thr Cys Ile Asn Gly Ile Trp Thr Glu Leu Pro Met Cys 
    290                 295                 300                 


Val Ala Thr His Gln Leu Lys Arg Cys Lys Ile Ala Gly Val Asn Ile 
305                 310                 315                 320 


Lys Thr Leu Leu Lys Leu Ser Gly Lys Glu Phe Asn His Asn Ser Arg 
                325                 330                 335     


Ile Arg Tyr Arg Cys Ser Asp Ile Phe Arg Tyr Arg His Ser Val Cys 
            340                 345                 350         


Ile Asn Gly Lys Trp Asn Pro Glu Val Asp Cys Thr Glu Lys Arg Glu 
        355                 360                 365             


Gln Phe Cys Pro Pro Pro Pro Gln Ile Pro Asn Ala Gln Asn Met Thr 
    370                 375                 380                 


Thr Thr Val Asn Tyr Gln Asp Gly Glu Lys Val Ala Val Leu Cys Lys 
385                 390                 395                 400 


Glu Asn Tyr Leu Leu Pro Glu Ala Lys Glu Ile Val Cys Lys Asp Gly 
                405                 410                 415     


Arg Trp Gln Ser Leu Pro Arg Cys Val Glu Ser Thr Ala Tyr Cys Gly 
            420                 425                 430         


Pro Pro Pro Ser Ile Asn Asn Gly Asp Thr Thr Ser Phe Pro Leu Ser 
        435                 440                 445             


Val Tyr Pro Pro Gly Ser Thr Val Thr Tyr Arg Cys Gln Ser Phe Tyr 
    450                 455                 460                 


Lys Leu Gln Gly Ser Val Thr Val Thr Cys Arg Asn Lys Gln Trp Ser 
465                 470                 475                 480 


Glu Pro Pro Arg Cys Leu Asp Pro Cys Val Val Ser Glu Glu Asn Met 
                485                 490                 495     


Asn Lys Asn Asn Ile Gln Leu Lys Trp Arg Asn Asp Gly Lys Leu Tyr 
            500                 505                 510         


Ala Lys Thr Gly Asp Ala Val Glu Phe Gln Cys Lys Phe Pro His Lys 
        515                 520                 525             


Ala Met Ile Ser Ser Pro Pro Phe Arg Ala Ile Cys Gln Glu Gly Lys 
    530                 535                 540                 


Phe Glu Tyr Pro Ile Cys Glu 
545                 550     


<210>  2879
<211>  204
<212>  PRT
<213>  Homo Sapiens

<400>  2879

Glu Ala Phe Asp Ser Val Leu Gly Asp Thr Ala Ser Cys His Arg Ala 
1               5                   10                  15      


Cys Gln Leu Thr Tyr Pro Leu His Thr Tyr Pro Lys Glu Glu Glu Leu 
            20                  25                  30          


Tyr Ala Cys Gln Arg Gly Cys Arg Leu Phe Ser Ile Cys Gln Phe Val 
        35                  40                  45              


Asp Asp Gly Ile Asp Leu Asn Arg Thr Lys Leu Glu Cys Glu Ser Ala 
    50                  55                  60                  


Cys Thr Glu Ala Tyr Ser Gln Ser Asp Glu Gln Tyr Ala Cys His Leu 
65                  70                  75                  80  


Gly Cys Gln Asn Gln Leu Pro Phe Ala Glu Leu Arg Gln Glu Gln Leu 
                85                  90                  95      


Met Ser Leu Met Pro Lys Met His Leu Leu Phe Pro Leu Thr Leu Val 
            100                 105                 110         


Arg Ser Phe Trp Ser Asp Met Met Asp Ser Ala Gln Ser Phe Ile Thr 
        115                 120                 125             


Ser Ser Trp Thr Phe Tyr Leu Gln Ala Asp Asp Gly Lys Ile Val Ile 
    130                 135                 140                 


Phe Gln Ser Lys Pro Glu Ile Gln Tyr Ala Pro His Leu Glu Gln Glu 
145                 150                 155                 160 


Pro Thr Asn Leu Arg Glu Ser Ser Leu Ser Lys Met Ser Ser Asp Leu 
                165                 170                 175     


Gln Met Arg Asn Ser Gln Ala His Arg Asn Phe Leu Glu Asp Gly Glu 
            180                 185                 190         


Ser Asp Gly Phe Leu Arg Cys Leu Ser Leu Asn Ser 
        195                 200                 


<210>  2880
<211>  251
<212>  PRT
<213>  Homo Sapiens

<400>  2880

Gln Asn Ala Ser Arg Gly Arg Arg Gln Arg Arg Met His Pro Asn Val 
1               5                   10                  15      


Ser Gln Gly Cys Gln Gly Gly Cys Ala Thr Cys Ser Asp Tyr Asn Gly 
            20                  25                  30          


Cys Leu Ser Cys Lys Pro Arg Leu Phe Phe Ala Leu Glu Arg Ile Gly 
        35                  40                  45              


Met Lys Gln Ile Gly Val Cys Leu Ser Ser Cys Pro Ser Gly Tyr Tyr 
    50                  55                  60                  


Gly Thr Arg Tyr Pro Asp Ile Asn Lys Cys Thr Lys Cys Lys Ala Asp 
65                  70                  75                  80  


Cys Asp Thr Cys Phe Asn Lys Asn Phe Cys Thr Lys Cys Lys Ser Gly 
                85                  90                  95      


Phe Tyr Leu His Leu Gly Lys Cys Leu Asp Asn Cys Pro Glu Gly Leu 
            100                 105                 110         


Glu Ala Asn Asn His Thr Met Glu Cys Val Ser Ile Val His Cys Glu 
        115                 120                 125             


Val Ser Glu Trp Asn Pro Trp Ser Pro Cys Thr Lys Lys Gly Lys Thr 
    130                 135                 140                 


Cys Gly Phe Lys Arg Gly Thr Glu Thr Arg Val Arg Glu Ile Ile Gln 
145                 150                 155                 160 


His Pro Ser Ala Lys Gly Asn Leu Cys Pro Pro Thr Asn Glu Thr Arg 
                165                 170                 175     


Lys Cys Thr Val Gln Arg Lys Lys Cys Gln Lys Gly Glu Arg Gly Lys 
            180                 185                 190         


Lys Gly Arg Glu Arg Lys Arg Lys Lys Pro Asn Lys Gly Glu Ser Lys 
        195                 200                 205             


Glu Ala Ile Pro Asp Ser Lys Ser Leu Glu Ser Ser Lys Glu Ile Pro 
    210                 215                 220                 


Glu Gln Arg Glu Asn Lys Gln Gln Gln Lys Lys Arg Lys Val Gln Asp 
225                 230                 235                 240 


Lys Gln Lys Ser Val Ser Val Ser Thr Val His 
                245                 250     


<210>  2881
<211>  381
<212>  PRT
<213>  Homo Sapiens

<400>  2881

Gln Phe Trp Gln Gly His Thr Gly Ile Arg Tyr Lys Glu Gln Arg Glu 
1               5                   10                  15      


Ser Cys Pro Lys His Ala Val Arg Cys Asp Gly Val Val Asp Cys Lys 
            20                  25                  30          


Leu Lys Ser Asp Glu Leu Gly Cys Val Arg Phe Asp Trp Asp Lys Ser 
        35                  40                  45              


Leu Leu Lys Ile Tyr Ser Gly Ser Ser His Gln Trp Leu Pro Ile Cys 
    50                  55                  60                  


Ser Ser Asn Trp Asn Asp Ser Tyr Ser Glu Lys Thr Cys Gln Gln Leu 
65                  70                  75                  80  


Gly Phe Glu Ser Ala His Arg Thr Thr Glu Val Ala His Arg Asp Phe 
                85                  90                  95      


Ala Asn Ser Phe Ser Ile Leu Arg Tyr Asn Ser Thr Ile Gln Glu Ser 
            100                 105                 110         


Leu His Arg Ser Glu Cys Pro Ser Gln Arg Tyr Ile Ser Leu Gln Cys 
        115                 120                 125             


Ser His Cys Gly Leu Arg Ala Met Thr Gly Arg Ile Val Gly Gly Ala 
    130                 135                 140                 


Leu Ala Ser Asp Ser Lys Trp Pro Trp Gln Val Ser Leu His Phe Gly 
145                 150                 155                 160 


Thr Thr His Ile Cys Gly Gly Thr Leu Ile Asp Ala Gln Trp Val Leu 
                165                 170                 175     


Thr Ala Ala His Cys Phe Phe Val Thr Arg Glu Lys Val Leu Glu Gly 
            180                 185                 190         


Trp Lys Val Tyr Ala Gly Thr Ser Asn Leu His Gln Leu Pro Glu Ala 
        195                 200                 205             


Ala Ser Ile Ala Glu Ile Ile Ile Asn Ser Asn Tyr Thr Asp Glu Glu 
    210                 215                 220                 


Asp Asp Tyr Asp Ile Ala Leu Met Arg Leu Ser Lys Pro Leu Thr Leu 
225                 230                 235                 240 


Ser Ala His Ile His Pro Ala Cys Leu Pro Met His Gly Gln Thr Phe 
                245                 250                 255     


Ser Leu Asn Glu Thr Cys Trp Ile Thr Gly Phe Gly Lys Thr Arg Glu 
            260                 265                 270         


Thr Asp Asp Lys Thr Ser Pro Phe Leu Arg Glu Val Gln Val Asn Leu 
        275                 280                 285             


Ile Asp Phe Lys Lys Cys Asn Asp Tyr Leu Val Tyr Asp Ser Tyr Leu 
    290                 295                 300                 


Thr Pro Arg Met Met Cys Ala Gly Asp Leu Arg Gly Gly Arg Asp Ser 
305                 310                 315                 320 


Cys Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Glu Gln Asn Asn Arg 
                325                 330                 335     


Trp Tyr Leu Ala Gly Val Thr Ser Trp Gly Thr Gly Cys Gly Gln Arg 
            340                 345                 350         


Asn Lys Pro Gly Val Tyr Thr Lys Val Thr Glu Val Leu Pro Trp Ile 
        355                 360                 365             


Tyr Ser Lys Met Glu Ser Glu Val Arg Phe Arg Lys Ser 
    370                 375                 380     


<210>  2882
<211>  1134
<212>  PRT
<213>  Homo Sapiens

<400>  2882

Asn Val Ala Pro Lys Phe Leu Ala Asn Met Thr Ser Val Ile Leu Pro 
1               5                   10                  15      


Glu Asp Leu Pro Val Gly Ala Gln Ala Phe Trp Leu Val Ala Glu Asp 
            20                  25                  30          


Gln Asp Asn Asp Pro Leu Thr Tyr Gly Met Ser Gly Pro Asn Ala Tyr 
        35                  40                  45              


Phe Phe Ala Val Thr Pro Lys Thr Gly Glu Val Lys Leu Ala Ser Ala 
    50                  55                  60                  


Leu Asp Tyr Glu Thr Leu Tyr Thr Phe Lys Val Thr Ile Ser Val Ser 
65                  70                  75                  80  


Asp Pro Tyr Ile Gln Val Gln Arg Glu Met Leu Val Ile Val Glu Asp 
                85                  90                  95      


Arg Asn Asp Asn Ala Pro Val Phe Gln Asn Thr Ala Phe Ser Thr Ser 
            100                 105                 110         


Ile Asn Glu Thr Leu Pro Val Gly Ser Val Val Phe Ser Val Leu Ala 
        115                 120                 125             


Val Asp Lys Asp Met Gly Ser Ala Gly Met Val Val Tyr Ser Ile Glu 
    130                 135                 140                 


Lys Val Ile Pro Ser Thr Gly Asp Ser Glu His Leu Phe Arg Ile Leu 
145                 150                 155                 160 


Ala Asn Gly Ser Ile Val Leu Asn Gly Ser Leu Ser Tyr Asn Asn Lys 
                165                 170                 175     


Ser Ala Phe Tyr Gln Leu Glu Leu Lys Ala Cys Asp Leu Gly Gly Met 
            180                 185                 190         


Tyr His Asn Thr Phe Thr Ile Gln Cys Ser Leu Pro Val Phe Leu Ser 
        195                 200                 205             


Ile Ser Val Val Asp Gln Pro Asp Leu Asp Pro Gln Phe Val Arg Glu 
    210                 215                 220                 


Phe Tyr Ser Ala Ser Val Ala Glu Asp Ala Ala Lys Gly Thr Ser Val 
225                 230                 235                 240 


Leu Thr Val Glu Ala Val Asp Gly Asp Lys Gly Ile Asn Asp Pro Val 
                245                 250                 255     


Ile Tyr Ser Ile Ser Tyr Ser Thr Arg Pro Gly Trp Phe Asp Ile Gly 
            260                 265                 270         


Ala Asp Gly Val Ile Arg Val Asn Gly Ser Leu Asp Arg Glu Gln Leu 
        275                 280                 285             


Leu Glu Ala Asp Glu Glu Val Gln Leu Gln Val Thr Ala Thr Glu Thr 
    290                 295                 300                 


His Leu Asn Ile Tyr Gly Gln Glu Ala Lys Val Ser Ile Trp Val Thr 
305                 310                 315                 320 


Val Arg Val Met Asp Val Asn Asp His Lys Pro Glu Phe Tyr Asn Cys 
                325                 330                 335     


Ser Leu Pro Ala Cys Thr Phe Thr Pro Glu Glu Ala Gln Val Asn Phe 
            340                 345                 350         


Thr Gly Tyr Val Asp Glu His Ala Ser Pro Arg Ile Pro Ile Asp Asp 
        355                 360                 365             


Leu Thr Met Val Val Tyr Asp Pro Asp Lys Gly Ser Asn Gly Thr Phe 
    370                 375                 380                 


Leu Leu Ser Leu Gly Gly Pro Asp Ala Glu Ala Phe Ser Val Ser Pro 
385                 390                 395                 400 


Glu Arg Ala Ala Gly Ser Ala Ser Val Gln Val Leu Val Arg Val Ser 
                405                 410                 415     


Ala Leu Val Asp Tyr Glu Arg Gln Thr Ala Met Ala Val Gln Val Val 
            420                 425                 430         


Ala Thr Asp Ser Val Ser Gln Asn Phe Ser Val Ala Met Val Thr Ile 
        435                 440                 445             


His Leu Arg Asp Ile Asn Asp His Arg Pro Thr Phe Pro Gln Ser Leu 
    450                 455                 460                 


Tyr Val Leu Thr Val Pro Glu His Ser Ala Thr Gly Ser Val Val Thr 
465                 470                 475                 480 


Asp Ser Ile His Ala Thr Asp Pro Asp Thr Gly Ala Trp Gly Gln Ile 
                485                 490                 495     


Thr Tyr Ser Leu Leu Pro Gly Asn Gly Ala Asp Leu Phe Gln Val Asp 
            500                 505                 510         


Pro Val Ser Gly Thr Val Thr Val Arg Asn Gly Glu Leu Leu Asp Arg 
        515                 520                 525             


Glu Ser Gln Ala Val Tyr Tyr Leu Thr Leu Gln Ala Thr Asp Gly Gly 
    530                 535                 540                 


Asn Leu Ser Ser Ser Thr Thr Leu Gln Ile His Leu Leu Asp Ile Asn 
545                 550                 555                 560 


Asp Asn Ala Pro Val Val Ser Gly Ser Tyr Asn Ile Phe Val Gln Glu 
                565                 570                 575     


Glu Glu Gly Asn Val Ser Val Thr Ile Gln Ala His Asp Asn Asp Glu 
            580                 585                 590         


Pro Gly Thr Asn Asn Ser Arg Leu Leu Phe Asn Leu Leu Pro Gly Pro 
        595                 600                 605             


Tyr Ser His Asn Phe Ser Leu Asp Pro Asp Thr Gly Leu Leu Arg Asn 
    610                 615                 620                 


Leu Gly Pro Leu Asp Arg Glu Ala Ile Asp Pro Ala Leu Glu Gly Arg 
625                 630                 635                 640 


Ile Val Leu Thr Val Leu Val Ser Asp Cys Gly Glu Pro Val Leu Gly 
                645                 650                 655     


Thr Lys Val Asn Val Thr Ile Thr Val Glu Asp Ile Asn Asp Asn Leu 
            660                 665                 670         


Pro Ile Phe Asn Gln Ser Ser Tyr Asn Phe Thr Val Lys Glu Glu Asp 
        675                 680                 685             


Pro Gly Val Leu Val Gly Val Val Lys Ala Trp Asp Ala Asp Gln Thr 
    690                 695                 700                 


Glu Ala Asn Asn Arg Ile Ser Phe Ser Leu Ser Gly Ser Gly Ala Asn 
705                 710                 715                 720 


Tyr Phe Met Ile Arg Gly Leu Val Leu Gly Ala Gly Trp Ala Glu Gly 
                725                 730                 735     


Tyr Leu Arg Leu Pro Pro Asp Val Ser Leu Asp Tyr Glu Thr Gln Pro 
            740                 745                 750         


Val Phe Asn Leu Thr Val Ser Ala Glu Asn Pro Asp Pro Gln Gly Gly 
        755                 760                 765             


Glu Thr Ile Val Asp Val Cys Val Asn Val Lys Asp Val Asn Asp Asn 
    770                 775                 780                 


Pro Pro Thr Leu Asp Val Ala Ser Leu Arg Gly Ile Arg Val Ala Glu 
785                 790                 795                 800 


Asn Gly Ser Gln His Gly Gln Val Ala Val Val Val Ala Ser Asp Val 
                805                 810                 815     


Asp Thr Ser Ala Gln Leu Glu Ile Gln Leu Val Asn Ile Leu Cys Thr 
            820                 825                 830         


Lys Ala Gly Val Asp Val Gly Ser Leu Cys Trp Gly Trp Phe Ser Val 
        835                 840                 845             


Ala Ala Asn Gly Ser Val Tyr Ile Asn Gln Ser Lys Ala Ile Asp Tyr 
    850                 855                 860                 


Glu Ala Cys Asp Leu Val Thr Leu Val Val Arg Ala Cys Asp Leu Ala 
865                 870                 875                 880 


Thr Asp Pro Gly Phe Gln Ala Tyr Ser Asn Asn Gly Ser Leu Leu Ile 
                885                 890                 895     


Thr Ile Glu Asp Val Asn Asp Asn Ala Pro Tyr Phe Leu Pro Glu Asn 
            900                 905                 910         


Lys Thr Phe Val Ile Ile Pro Glu Leu Val Leu Pro Asn Arg Glu Val 
        915                 920                 925             


Ala Ser Val Arg Ala Arg Asp Asp Asp Ser Gly Asn Asn Gly Val Ile 
    930                 935                 940                 


Leu Phe Ser Ile Leu Arg Val Asp Phe Ile Ser Lys Asp Gly Ala Thr 
945                 950                 955                 960 


Ile Pro Phe Gln Gly Val Phe Ser Ile Phe Thr Ser Ser Glu Ala Asp 
                965                 970                 975     


Val Phe Ala Gly Ser Ile Gln Pro Val Thr Ser Leu Asp Ser Thr Leu 
            980                 985                 990         


Gln Gly Thr Tyr Gln Val Thr Val  Gln Ala Arg Asp Arg  Pro Ser Leu 
        995                 1000                 1005             


Gly Pro  Phe Leu Glu Ala Thr  Thr Thr Leu Asn Leu  Phe Thr Val 
    1010                 1015                 1020             


Asp Gln  Ser Tyr Arg Ser Arg  Leu Gln Phe Ser Thr  Pro Lys Glu 
    1025                 1030                 1035             


Glu Val  Gly Ala Asn Arg Gln  Ala Ile Asn Ala Ala  Leu Thr Gln 
    1040                 1045                 1050             


Ala Thr  Arg Thr Thr Val Tyr  Ile Val Asp Ile Gln  Asp Ile Asp 
    1055                 1060                 1065             


Ser Ala  Ala Arg Ala Arg Pro  His Ser Tyr Leu Asp  Ala Tyr Phe 
    1070                 1075                 1080             


Val Phe  Pro Asn Gly Ser Ala  Leu Thr Leu Asp Glu  Leu Ser Val 
    1085                 1090                 1095             


Met Ile  Arg Asn Asp Gln Asp  Ser Leu Met Gln Leu  Leu Gln Leu 
    1100                 1105                 1110             


Gly Leu  Val Val Leu Gly Ser  Gln Glu Ser Gln Glu  Ser Asp Leu 
    1115                 1120                 1125             


Ser Lys  Gln Leu Ile Ser 
    1130                 


<210>  2883
<211>  64
<212>  PRT
<213>  Homo Sapiens

<400>  2883

Leu Leu Tyr Asn Arg Phe Asp Leu Glu Leu Phe Thr Pro Gly Asn Leu 
1               5                   10                  15      


Glu Arg Glu Cys Asn Glu Glu Leu Cys Asn Tyr Glu Glu Ala Arg Glu 
            20                  25                  30          


Ile Phe Val Asp Glu Asp Lys Thr Ile Ala Phe Trp Gln Glu Tyr Ser 
        35                  40                  45              


Ala Lys Gly Pro Thr Thr Lys Ser Asp Gly Asn Arg Glu Lys Ile Asp 
    50                  55                  60                  


<210>  2884
<211>  59
<212>  PRT
<213>  Homo Sapiens

<400>  2884

Ala Asn Glu Phe Leu Glu Glu Leu Arg Gln Gly Thr Ile Glu Arg Glu 
1               5                   10                  15      


Cys Met Glu Glu Ile Cys Ser Tyr Glu Glu Val Lys Glu Val Phe Glu 
            20                  25                  30          


Asn Lys Glu Lys Thr Met Glu Phe Trp Lys Gly Tyr Pro Asn Ala Val 
        35                  40                  45              


Tyr Ser Val Arg Asp Pro Ser Gln Ser Ser Asp 
    50                  55                  


<210>  2885
<211>  367
<212>  PRT
<213>  Homo Sapiens

<400>  2885

Leu Pro Glu Gly Pro Leu Val Phe Val Ala Leu Val Phe Arg His Gly 
1               5                   10                  15      


Asp Arg Ala Pro Leu Ala Ser Tyr Pro Met Asp Pro His Lys Glu Val 
            20                  25                  30          


Ala Ser Thr Leu Trp Pro Arg Gly Leu Gly Gln Leu Thr Thr Glu Gly 
        35                  40                  45              


Val Arg Gln Gln Leu Glu Leu Gly Arg Phe Leu Arg Ser Arg Tyr Glu 
    50                  55                  60                  


Ala Phe Leu Ser Pro Glu Tyr Arg Arg Glu Glu Val Tyr Ile Arg Ser 
65                  70                  75                  80  


Thr Asp Phe Asp Arg Thr Leu Glu Ser Ala Gln Ala Asn Leu Ala Gly 
                85                  90                  95      


Leu Phe Pro Glu Ala Ala Pro Gly Ser Pro Glu Ala Arg Trp Arg Pro 
            100                 105                 110         


Ile Pro Val His Thr Val Pro Val Ala Glu Asp Lys Leu Leu Arg Phe 
        115                 120                 125             


Pro Met Arg Ser Cys Pro Arg Tyr His Glu Leu Leu Arg Glu Ala Thr 
    130                 135                 140                 


Glu Ala Ala Glu Tyr Gln Glu Ala Leu Glu Gly Trp Thr Gly Phe Leu 
145                 150                 155                 160 


Ser Arg Leu Glu Asn Phe Thr Gly Leu Ser Leu Val Gly Glu Pro Leu 
                165                 170                 175     


Arg Arg Ala Trp Lys Val Leu Asp Thr Leu Met Cys Gln Gln Ala His 
            180                 185                 190         


Gly Leu Pro Leu Pro Ala Trp Ala Ser Pro Asp Val Leu Arg Thr Leu 
        195                 200                 205             


Ala Gln Ile Ser Ala Leu Asp Ile Gly Ala His Val Gly Pro Pro Arg 
    210                 215                 220                 


Ala Ala Glu Lys Ala Gln Leu Thr Gly Gly Ile Leu Leu Asn Ala Ile 
225                 230                 235                 240 


Leu Ala Asn Phe Ser Arg Val Gln Arg Leu Gly Leu Pro Leu Lys Met 
                245                 250                 255     


Val Met Tyr Ser Ala His Asp Ser Thr Leu Leu Ala Leu Gln Gly Ala 
            260                 265                 270         


Leu Gly Leu Tyr Asp Gly His Thr Pro Pro Tyr Ala Ala Cys Leu Gly 
        275                 280                 285             


Phe Glu Phe Arg Lys His Leu Gly Asn Pro Ala Lys Asp Gly Gly Asn 
    290                 295                 300                 


Val Thr Val Ser Leu Phe Tyr Arg Asn Asp Ser Ala His Leu Pro Leu 
305                 310                 315                 320 


Pro Leu Ser Leu Pro Gly Cys Pro Ala Pro Cys Pro Leu Gly Arg Phe 
                325                 330                 335     


Tyr Gln Leu Thr Ala Pro Ala Arg Pro Pro Ala His Gly Val Ser Cys 
            340                 345                 350         


His Gly Pro Tyr Glu Ala Ala Ile Pro Pro Ala Pro Val Val Pro 
        355                 360                 365         


<210>  2886
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  2886

Gln Glu Gln Ala Gln Thr Thr Asp Trp Arg Ala Thr Leu Lys Thr Ile 
1               5                   10                  15      


Arg Asn Gly Val His Lys Ile Asp Thr Tyr Leu Asn Ala Ala Leu Asp 
            20                  25                  30          


Leu Leu Gly Gly Glu Asp Gly Leu Cys Gln Tyr Lys Cys Ser Asp Gly 
        35                  40                  45              


Ser Lys Pro Phe Pro Arg Tyr Gly Tyr Lys Pro Ser Pro Pro Asn Gly 
    50                  55                  60                  


Cys Gly Ser Pro Leu Phe Gly Val His Leu Asn Ile Gly Ile Pro Ser 
65                  70                  75                  80  


Leu Thr Lys Cys Cys Asn Gln His Asp Arg Cys Tyr Glu Thr Cys Gly 
                85                  90                  95      


Lys Ser Lys Asn Asp Cys Asp Glu Glu Phe Gln Tyr Cys Leu Ser Lys 
            100                 105                 110         


Ile Cys Arg Asp Val Gln Lys Thr Leu Gly Leu Thr Gln His Val Gln 
        115                 120                 125             


Ala Cys Glu Thr Thr Val Glu Leu Leu Phe Asp Ser Val Ile His Leu 
    130                 135                 140                 


Gly Cys Lys Pro Tyr Leu Asp Ser Gln Arg Ala Ala Cys Arg Cys His 
145                 150                 155                 160 


Tyr Glu Glu Lys Thr Asp Leu 
                165         


<210>  2887
<211>  148
<212>  PRT
<213>  Homo Sapiens

<400>  2887

Ser Leu Leu Asn Leu Lys Ala Met Val Glu Ala Val Thr Gly Arg Ser 
1               5                   10                  15      


Ala Ile Leu Ser Phe Val Gly Tyr Gly Cys Tyr Cys Gly Leu Gly Gly 
            20                  25                  30          


Arg Gly Gln Pro Lys Asp Glu Val Asp Trp Cys Cys His Ala His Asp 
        35                  40                  45              


Cys Cys Tyr Gln Glu Leu Phe Asp Gln Gly Cys His Pro Tyr Val Asp 
    50                  55                  60                  


His Tyr Asp His Thr Ile Glu Asn Asn Thr Glu Ile Val Cys Ser Asp 
65                  70                  75                  80  


Leu Asn Lys Thr Glu Cys Asp Lys Gln Thr Cys Met Cys Asp Lys Asn 
                85                  90                  95      


Met Val Leu Cys Leu Met Asn Gln Thr Tyr Arg Glu Glu Tyr Arg Gly 
            100                 105                 110         


Phe Leu Asn Val Tyr Cys Gln Gly Pro Thr Pro Asn Cys Ser Ile Tyr 
        115                 120                 125             


Glu Pro Pro Pro Glu Glu Val Thr Cys Ser His Gln Ser Pro Ala Pro 
    130                 135                 140                 


Pro Ala Pro Pro 
145             


<210>  2888
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  2888

Arg Arg Asp Asp Pro His Ser Leu Cys Tyr Asp Ile Thr Val Ile Pro 
1               5                   10                  15      


Lys Phe Arg Pro Gly Pro Arg Trp Cys Ala Val Gln Gly Gln Val Asp 
            20                  25                  30          


Glu Lys Thr Phe Leu His Tyr Asp Cys Gly Asn Lys Thr Val Thr Pro 
        35                  40                  45              


Val Ser Pro Leu Gly Lys Lys Leu Asn Val Thr Met Ala Trp Lys Ala 
    50                  55                  60                  


Gln Asn Pro Val Leu Arg Glu Val Val Asp Ile Leu Thr Glu Gln Leu 
65                  70                  75                  80  


Leu Asp Ile Gln Leu Glu Asn Tyr Thr Pro Lys Glu Pro Leu Thr Leu 
                85                  90                  95      


Gln Ala Arg Met Ser Cys Glu Gln Lys Ala Glu Gly His Ser Ser Gly 
            100                 105                 110         


Ser Trp Gln Phe Ser Ile Asp Gly Gln Thr Phe Leu Leu Phe Asp Ser 
        115                 120                 125             


Glu Lys Arg Met Trp Thr Thr Val His Pro Gly Ala Arg Lys Met Lys 
    130                 135                 140                 


Glu Lys Trp Glu Asn Asp Lys Asp Val Ala Met Ser Phe His Tyr Ile 
145                 150                 155                 160 


Ser Met Gly Asp Cys Ile Gly Trp Leu Glu Asp Phe Leu Met Gly Met 
                165                 170                 175     


Asp Ser Thr Leu Glu Pro Ser Ala Gly Ala Pro Leu Ala Met Ser 
            180                 185                 190     


<210>  2889
<211>  191
<212>  PRT
<213>  Homo Sapiens

<400>  2889

Gly Trp Val Asp Thr His Cys Leu Cys Tyr Asp Phe Ile Ile Thr Pro 
1               5                   10                  15      


Lys Ser Arg Pro Glu Pro Gln Trp Cys Glu Val Gln Gly Leu Val Asp 
            20                  25                  30          


Glu Arg Pro Phe Leu His Tyr Asp Cys Val Asn His Lys Ala Lys Ala 
        35                  40                  45              


Phe Ala Ser Leu Gly Lys Lys Val Asn Val Thr Lys Thr Trp Glu Glu 
    50                  55                  60                  


Gln Thr Glu Thr Leu Arg Asp Val Val Asp Phe Leu Lys Gly Gln Leu 
65                  70                  75                  80  


Leu Asp Ile Gln Val Glu Asn Leu Ile Pro Ile Glu Pro Leu Thr Leu 
                85                  90                  95      


Gln Ala Arg Met Ser Cys Glu His Glu Ala His Gly His Gly Arg Gly 
            100                 105                 110         


Ser Trp Gln Phe Leu Phe Asn Gly Gln Lys Phe Leu Leu Phe Asp Ser 
        115                 120                 125             


Asn Asn Arg Lys Trp Thr Ala Leu His Pro Gly Ala Lys Lys Met Thr 
    130                 135                 140                 


Glu Lys Trp Glu Lys Asn Arg Asp Val Thr Met Phe Phe Gln Lys Ile 
145                 150                 155                 160 


Ser Leu Gly Asp Cys Lys Met Trp Leu Glu Glu Phe Leu Met Tyr Trp 
                165                 170                 175     


Glu Gln Met Leu Asp Pro Thr Lys Pro Pro Ser Leu Ala Pro Gly 
            180                 185                 190     


<210>  2890
<211>  750
<212>  PRT
<213>  Homo Sapiens

<400>  2890

Val Ser Ala Thr Ala Ala Ala Val Val Pro Glu Gln His Ala Ser Val 
1               5                   10                  15      


Ala Gly Gln His Pro Leu Asp Trp Leu Leu Thr Asp Arg Gly Pro Phe 
            20                  25                  30          


His Arg Ala Gln Glu Tyr Ala Asp Phe Met Glu Arg Tyr Arg Gln Gly 
        35                  40                  45              


Phe Thr Thr Arg Tyr Arg Ile Tyr Arg Glu Phe Ala Arg Trp Lys Val 
    50                  55                  60                  


Asn Asn Leu Ala Leu Glu Arg Lys Asp Phe Phe Ser Leu Pro Leu Pro 
65                  70                  75                  80  


Leu Ala Pro Glu Phe Ile Arg Asn Ile Arg Leu Leu Gly Arg Arg Pro 
                85                  90                  95      


Asn Leu Gln Gln Val Thr Glu Asn Leu Ile Lys Lys Tyr Gly Thr His 
            100                 105                 110         


Phe Leu Leu Ser Ala Thr Leu Gly Gly Glu Glu Ser Leu Thr Ile Phe 
        115                 120                 125             


Val Asp Lys Gln Lys Leu Gly Arg Lys Thr Glu Thr Thr Gly Gly Ala 
    130                 135                 140                 


Ser Ile Ile Gly Gly Ser Gly Asn Ser Thr Ala Val Ser Leu Glu Thr 
145                 150                 155                 160 


Leu His Gln Leu Ala Ala Ser Tyr Phe Ile Asp Arg Glu Ser Thr Leu 
                165                 170                 175     


Arg Arg Leu His His Ile Gln Ile Ala Thr Gly Ala Ile Lys Val Thr 
            180                 185                 190         


Glu Thr Arg Thr Gly Pro Leu Gly Cys Ser Asn Tyr Asp Asn Leu Asp 
        195                 200                 205             


Ser Val Ser Ser Val Leu Val Gln Ser Pro Glu Asn Lys Val Gln Leu 
    210                 215                 220                 


Leu Gly Leu Gln Val Leu Leu Pro Glu Tyr Leu Arg Glu Arg Phe Val 
225                 230                 235                 240 


Ala Ala Ala Leu Ser Tyr Ile Thr Cys Ser Ser Glu Gly Glu Leu Val 
                245                 250                 255     


Cys Lys Glu Asn Asp Cys Trp Cys Lys Cys Ser Pro Thr Phe Pro Glu 
            260                 265                 270         


Cys Asn Cys Pro Asp Ala Asp Ile Gln Ala Met Glu Asp Ser Leu Leu 
        275                 280                 285             


Gln Ile Gln Asp Ser Trp Ala Thr His Asn Arg Gln Phe Glu Glu Ser 
    290                 295                 300                 


Glu Glu Phe Gln Ala Leu Leu Lys Arg Leu Pro Asp Asp Arg Phe Leu 
305                 310                 315                 320 


Asn Ser Thr Ala Ile Ser Gln Phe Trp Ala Met Asp Thr Ser Leu Gln 
                325                 330                 335     


His Arg Tyr Gln Gln Leu Gly Ala Gly Leu Lys Val Leu Phe Lys Lys 
            340                 345                 350         


Thr His Arg Ile Leu Arg Arg Leu Phe Asn Leu Cys Lys Arg Cys His 
        355                 360                 365             


Arg Gln Pro Arg Phe Arg Leu Pro Lys Glu Arg Ser Leu Ser Tyr Trp 
    370                 375                 380                 


Trp Asn Arg Ile Gln Ser Leu Leu Tyr Cys Gly Glu Ser Thr Phe Pro 
385                 390                 395                 400 


Gly Thr Phe Leu Glu Gln Ser His Ser Cys Thr Cys Pro Tyr Asp Gln 
                405                 410                 415     


Ser Ser Cys Gln Gly Pro Ile Pro Cys Ala Leu Gly Glu Gly Pro Ala 
            420                 425                 430         


Cys Ala His Cys Ala Pro Asp Asn Ser Thr Arg Cys Gly Ser Cys Asn 
        435                 440                 445             


Pro Gly Tyr Val Leu Ala Gln Gly Leu Cys Arg Pro Glu Val Ala Glu 
    450                 455                 460                 


Ser Leu Glu Asn Phe Leu Gly Leu Glu Thr Asp Leu Gln Asp Leu Glu 
465                 470                 475                 480 


Leu Lys Tyr Leu Leu Gln Lys Gln Asp Ser Arg Ile Glu Val His Ser 
                485                 490                 495     


Ile Phe Ile Ser Asn Asp Met Arg Leu Gly Ser Trp Phe Asp Pro Ser 
            500                 505                 510         


Trp Arg Lys Arg Met Leu Leu Thr Leu Lys Ser Asn Lys Tyr Lys Pro 
        515                 520                 525             


Gly Leu Val His Val Met Leu Ala Leu Ser Leu Gln Ile Cys Leu Thr 
    530                 535                 540                 


Lys Asn Ser Thr Leu Glu Pro Val Met Ala Ile Tyr Val Asn Pro Phe 
545                 550                 555                 560 


Gly Gly Ser His Ser Glu Ser Trp Phe Met Pro Val Asn Glu Gly Ser 
                565                 570                 575     


Phe Pro Asp Trp Glu Arg Thr Asn Val Asp Ala Ala Ala Gln Cys Gln 
            580                 585                 590         


Asn Trp Thr Ile Thr Leu Gly Asn Arg Trp Lys Thr Phe Phe Glu Thr 
        595                 600                 605             


Val His Val Tyr Leu Arg Ser Arg Ile Lys Ser Leu Asp Asp Ser Ser 
    610                 615                 620                 


Asn Glu Thr Ile Tyr Tyr Glu Pro Leu Glu Met Thr Asp Pro Ser Lys 
625                 630                 635                 640 


Asn Leu Gly Tyr Met Lys Ile Asn Thr Leu Gln Val Phe Gly Tyr Ser 
                645                 650                 655     


Leu Pro Phe Asp Pro Asp Ala Ile Arg Asp Leu Ile Leu Gln Leu Asp 
            660                 665                 670         


Tyr Pro Tyr Thr Gln Gly Ser Gln Asp Ser Ala Leu Leu Gln Leu Ile 
        675                 680                 685             


Glu Leu Arg Asp Arg Val Asn Gln Leu Ser Pro Pro Gly Lys Val Arg 
    690                 695                 700                 


Leu Asp Leu Phe Ser Cys Leu Leu Arg His Arg Leu Lys Leu Ala Asn 
705                 710                 715                 720 


Asn Glu Val Gly Arg Ile Gln Ser Ser Leu Arg Ala Phe Asn Ser Lys 
                725                 730                 735     


Leu Pro Asn Pro Val Glu Tyr Glu Thr Gly Lys Leu Cys Ser 
            740                 745                 750 


<210>  2891
<211>  129
<212>  PRT
<213>  Homo Sapiens

<400>  2891

Gly Leu Glu Leu Ala Val Ser Val Gly Ser Ser Asp Phe Cys Val Asp 
1               5                   10                  15      


Pro Asp Ala Tyr Val Thr Lys Met Val Glu Glu Tyr Ser Val Leu Ser 
            20                  25                  30          


Gly Asp Ile Leu Gln Tyr Tyr Leu Ala Cys Ser Pro Arg Ala Ala Asn 
        35                  40                  45              


Pro Phe Gln Gln Lys Leu Ser Gly Ser His Lys Ala Leu Val Glu Met 
    50                  55                  60                  


Gln Asp Val Val Ala Glu Leu Leu Arg Thr Val Pro Trp Glu Gln Pro 
65                  70                  75                  80  


Ala Thr Lys Asp Pro Leu Leu Arg Val Gln Glu Val Leu Asn Gly Thr 
                85                  90                  95      


Glu Val Asn Leu Gln His Leu Thr Ala Leu Val Asp Cys Arg Ser Leu 
            100                 105                 110         


His Leu Asp Tyr Val Gln Ala Leu Thr Gly Phe Cys Tyr Asp Gly Val 
        115                 120                 125             


Glu 
    


<210>  2892
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  2892

Glu Arg Met Leu Lys Met Leu Leu Lys Thr Tyr Gly Gln Asn Gly His 
1               5                   10                  15      


Thr His Phe Gly Asn Asp Asn Phe Gly Pro Gln Glu Lys Thr His Gln 
            20                  25                  30          


Pro Lys Ala Leu Pro Ala Ile Asn Gly Val Thr Cys Tyr Ala Asn Pro 
        35                  40                  45              


Ala Val Thr Glu Ala Asn Gly His Ile His Phe Asp Asn Val Ser Val 
    50                  55                  60                  


Val Ser Leu Gln Asp Gly Lys Lys Glu Pro Ser Ser Cys Thr Cys Leu 
65                  70                  75                  80  


Lys Gly Pro Lys Leu Ser Glu Ile Gly Thr 
                85                  90  


<210>  2893
<211>  446
<212>  PRT
<213>  Homo Sapiens

<400>  2893

Ala Gln Gln Gly Arg Gly Arg Arg Glu Leu Ala Pro Gly Leu His Leu 
1               5                   10                  15      


Arg Gly Ile Arg Asp Ala Gly Gly Arg Tyr Cys Gln Glu Gln Asp Leu 
            20                  25                  30          


Cys Cys Arg Gly Arg Ala Asp Asp Cys Ala Leu Pro Tyr Leu Gly Ala 
        35                  40                  45              


Ile Cys Tyr Cys Asp Leu Phe Cys Asn Arg Thr Val Ser Asp Cys Cys 
    50                  55                  60                  


Pro Asp Phe Trp Asp Phe Cys Leu Gly Val Pro Pro Pro Phe Pro Pro 
65                  70                  75                  80  


Ile Gln Gly Cys Met His Gly Gly Arg Ile Tyr Pro Val Leu Gly Thr 
                85                  90                  95      


Tyr Trp Asp Asn Cys Asn Arg Cys Thr Cys Gln Glu Asn Arg Gln Trp 
            100                 105                 110         


Gln Cys Asp Gln Glu Pro Cys Leu Val Asp Pro Asp Met Ile Lys Ala 
        115                 120                 125             


Ile Asn Gln Gly Asn Tyr Gly Trp Gln Ala Gly Asn His Ser Ala Phe 
    130                 135                 140                 


Trp Gly Met Thr Leu Asp Glu Gly Ile Arg Tyr Arg Leu Gly Thr Ile 
145                 150                 155                 160 


Arg Pro Ser Ser Ser Val Met Asn Met His Glu Ile Tyr Thr Val Leu 
                165                 170                 175     


Asn Pro Gly Glu Val Leu Pro Thr Ala Phe Glu Ala Ser Glu Lys Trp 
            180                 185                 190         


Pro Asn Leu Ile His Glu Pro Leu Asp Gln Gly Asn Cys Ala Gly Ser 
        195                 200                 205             


Trp Ala Phe Ser Thr Ala Ala Val Ala Ser Asp Arg Val Ser Ile His 
    210                 215                 220                 


Ser Leu Gly His Met Thr Pro Val Leu Ser Pro Gln Asn Leu Leu Ser 
225                 230                 235                 240 


Cys Asp Thr His Gln Gln Gln Gly Cys Arg Gly Gly Arg Leu Asp Gly 
                245                 250                 255     


Ala Trp Trp Phe Leu Arg Arg Arg Gly Val Val Ser Asp His Cys Tyr 
            260                 265                 270         


Pro Phe Ser Gly Arg Glu Arg Asp Glu Ala Gly Pro Ala Pro Pro Cys 
        275                 280                 285             


Met Met His Ser Arg Ala Met Gly Arg Gly Lys Arg Gln Ala Thr Ala 
    290                 295                 300                 


His Cys Pro Asn Ser Tyr Val Asn Asn Asn Asp Ile Tyr Gln Val Thr 
305                 310                 315                 320 


Pro Val Tyr Arg Leu Gly Ser Asn Asp Lys Glu Ile Met Lys Glu Leu 
                325                 330                 335     


Met Glu Asn Gly Pro Val Gln Ala Leu Met Glu Val His Glu Asp Phe 
            340                 345                 350         


Phe Leu Tyr Lys Gly Gly Ile Tyr Ser His Thr Pro Val Ser Leu Gly 
        355                 360                 365             


Arg Pro Glu Arg Tyr Arg Arg His Gly Thr His Ser Val Lys Ile Thr 
    370                 375                 380                 


Gly Trp Gly Glu Glu Thr Leu Pro Asp Gly Arg Thr Leu Lys Tyr Trp 
385                 390                 395                 400 


Thr Ala Ala Asn Ser Trp Gly Pro Ala Trp Gly Glu Arg Gly His Phe 
                405                 410                 415     


Arg Ile Val Arg Gly Val Asn Glu Cys Asp Ile Glu Ser Phe Val Leu 
            420                 425                 430         


Gly Val Trp Gly Arg Val Gly Met Glu Asp Met Gly His His 
        435                 440                 445     


<210>  2894
<211>  285
<212>  PRT
<213>  Homo Sapiens

<400>  2894

Ala Arg Ile Pro Val Pro Pro Ala Cys Gly Lys Pro Gln Gln Leu Asn 
1               5                   10                  15      


Arg Val Val Gly Gly Glu Asp Ser Thr Asp Ser Glu Trp Pro Trp Ile 
            20                  25                  30          


Val Ser Ile Gln Lys Asn Gly Thr His His Cys Ala Gly Ser Leu Leu 
        35                  40                  45              


Thr Ser Arg Trp Val Ile Thr Ala Ala His Cys Phe Lys Asp Asn Leu 
    50                  55                  60                  


Asn Lys Pro Tyr Leu Phe Ser Val Leu Leu Gly Ala Trp Gln Leu Gly 
65                  70                  75                  80  


Asn Pro Gly Ser Arg Ser Gln Lys Val Gly Val Ala Trp Val Glu Pro 
                85                  90                  95      


His Pro Val Tyr Ser Trp Lys Glu Gly Ala Cys Ala Asp Ile Ala Leu 
            100                 105                 110         


Val Arg Leu Glu Arg Ser Ile Gln Phe Ser Glu Arg Val Leu Pro Ile 
        115                 120                 125             


Cys Leu Pro Asp Ala Ser Ile His Leu Pro Pro Asn Thr His Cys Trp 
    130                 135                 140                 


Ile Ser Gly Trp Gly Ser Ile Gln Asp Gly Val Pro Leu Pro His Pro 
145                 150                 155                 160 


Gln Thr Leu Gln Lys Leu Lys Val Pro Ile Ile Asp Ser Glu Val Cys 
                165                 170                 175     


Ser His Leu Tyr Trp Arg Gly Ala Gly Gln Gly Pro Ile Thr Glu Asp 
            180                 185                 190         


Met Leu Cys Ala Gly Tyr Leu Glu Gly Glu Arg Asp Ala Cys Leu Gly 
        195                 200                 205             


Asp Ser Gly Gly Pro Leu Met Cys Gln Val Asp Gly Ala Trp Leu Leu 
    210                 215                 220                 


Ala Gly Ile Ile Ser Trp Gly Glu Gly Cys Ala Glu Arg Asn Arg Pro 
225                 230                 235                 240 


Gly Val Tyr Ile Ser Leu Ser Ala His Arg Ser Trp Val Glu Lys Ile 
                245                 250                 255     


Val Gln Gly Val Gln Leu Arg Gly Arg Ala Gln Gly Gly Gly Ala Leu 
            260                 265                 270         


Arg Ala Pro Ser Gln Gly Ser Gly Ala Ala Ala Arg Ser 
        275                 280                 285 


<210>  2895
<211>  382
<212>  PRT
<213>  Homo Sapiens

<400>  2895

Met Pro Arg Ser Ala Pro Asn Asp Ile Leu Asp Leu Arg Leu Pro Pro 
1               5                   10                  15      


Glu Pro Val Leu Asn Ala Asn Thr Val Cys Leu Thr Leu Pro Gly Leu 
            20                  25                  30          


Ser Arg Arg Gln Met Glu Val Cys Val Arg His Pro Asp Val Ala Ala 
        35                  40                  45              


Ser Ala Ile Gln Gly Ile Gln Ile Ala Ile His Glu Cys Gln His Gln 
    50                  55                  60                  


Phe Arg Asp Gln Arg Trp Asn Cys Ser Ser Leu Glu Thr Arg Asn Lys 
65                  70                  75                  80  


Ile Pro Tyr Glu Ser Pro Ile Phe Ser Arg Gly Phe Arg Glu Ser Ala 
                85                  90                  95      


Phe Ala Tyr Ala Ile Ala Ala Ala Gly Val Val His Ala Val Ser Asn 
            100                 105                 110         


Ala Cys Ala Leu Gly Lys Leu Lys Ala Cys Gly Cys Asp Ala Ser Arg 
        115                 120                 125             


Arg Gly Asp Glu Glu Ala Phe Arg Arg Lys Leu His Arg Leu Gln Leu 
    130                 135                 140                 


Asp Ala Leu Gln Arg Gly Lys Gly Leu Ser His Gly Val Pro Glu His 
145                 150                 155                 160 


Pro Ala Leu Pro Thr Ala Ser Pro Gly Leu Gln Asp Ser Trp Glu Trp 
                165                 170                 175     


Gly Gly Cys Ser Pro Asp Met Gly Phe Gly Glu Arg Phe Ser Lys Asp 
            180                 185                 190         


Phe Leu Asp Ser Arg Glu Pro His Arg Asp Ile His Ala Arg Met Arg 
        195                 200                 205             


Leu His Asn Asn Arg Val Gly Arg Gln Ala Val Met Glu Asn Met Arg 
    210                 215                 220                 


Arg Lys Cys Lys Cys His Gly Thr Ser Gly Ser Cys Gln Leu Lys Thr 
225                 230                 235                 240 


Cys Trp Gln Val Thr Pro Glu Phe Arg Thr Val Gly Ala Leu Leu Arg 
                245                 250                 255     


Ser Arg Phe His Arg Ala Thr Leu Ile Arg Pro His Asn Arg Asn Gly 
            260                 265                 270         


Gly Gln Leu Glu Pro Gly Pro Ala Gly Ala Pro Ser Pro Ala Pro Gly 
        275                 280                 285             


Ala Pro Gly Pro Arg Arg Arg Ala Ser Pro Ala Asp Leu Val Tyr Phe 
    290                 295                 300                 


Glu Lys Ser Pro Asp Phe Cys Glu Arg Glu Pro Arg Leu Asp Ser Ala 
305                 310                 315                 320 


Gly Thr Val Gly Arg Leu Cys Asn Lys Ser Ser Ala Gly Ser Asp Gly 
                325                 330                 335     


Cys Gly Ser Met Cys Cys Gly Arg Gly His Asn Ile Leu Arg Gln Thr 
            340                 345                 350         


Arg Ser Glu Arg Cys His Cys Arg Phe His Trp Cys Cys Phe Val Val 
        355                 360                 365             


Cys Glu Glu Cys Arg Ile Thr Glu Trp Val Ser Val Cys Lys 
    370                 375                 380         


<210>  2896
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  2896

Cys Asn Lys Ala Leu Cys Ala Ser Asp Val Ser Lys Cys Leu Ile Gln 
1               5                   10                  15      


Glu Leu Cys Gln Cys Arg Pro Gly Glu Gly Asn Cys Ser Cys Cys Lys 
            20                  25                  30          


Glu Cys Met Leu Cys Leu Gly Ala Leu Trp Asp Glu Cys Cys Asp Cys 
        35                  40                  45              


Val Gly Met Cys Asn Pro Arg Asn Tyr Ser Asp Thr Pro Pro Thr Ser 
    50                  55                  60                  


Lys Ser Thr Val Glu Glu Leu His Glu Pro Ile Pro Ser Leu Phe Arg 
65                  70                  75                  80  


Ala Leu Thr Glu Gly Asp Thr Gln Leu Asn Trp Asn Ile Val Ser Phe 
                85                  90                  95      


Pro Val Ala Glu Glu Leu Ser His His Glu Asn Leu Val Ser Phe Leu 
            100                 105                 110         


Glu Thr Val Asn Gln Pro His His Gln Asn Val Ser Val Pro Ser Asn 
        115                 120                 125             


Asn Val His Ala Pro Tyr Ser Ser Asp Lys Glu His Met Cys Thr Val 
    130                 135                 140                 


Val Tyr Phe Asp Asp Cys Met Ser Ile His Gln Cys Lys Ile Ser Cys 
145                 150                 155                 160 


Glu Ser Met Gly Ala Ser Lys Tyr Arg Trp Phe His Asn Ala Cys Cys 
                165                 170                 175     


Glu Cys Ile Gly Pro Glu Cys Ile Asp Tyr Gly Ser Lys Thr Val Lys 
            180                 185                 190         


Cys Met Asn Cys Met Phe 
        195             


<210>  2897
<211>  213
<212>  PRT
<213>  Homo Sapiens

<400>  2897

Ala Glu Gly Arg Leu Ala Leu Lys Leu Phe Arg Asp Leu Phe Ala Asn 
1               5                   10                  15      


Tyr Thr Ser Ala Leu Arg Pro Val Ala Asp Thr Asp Gln Thr Leu Asn 
            20                  25                  30          


Val Thr Leu Glu Val Thr Leu Ser Gln Ile Ile Asp Met Asp Glu Arg 
        35                  40                  45              


Asn Gln Val Leu Thr Leu Tyr Leu Trp Ile Arg Gln Glu Trp Thr Asp 
    50                  55                  60                  


Ala Tyr Leu Arg Trp Asp Pro Asn Ala Tyr Gly Gly Leu Asp Ala Ile 
65                  70                  75                  80  


Arg Ile Pro Ser Ser Leu Val Trp Arg Pro Asp Ile Val Leu Tyr Asn 
                85                  90                  95      


Lys Ala Asp Ala Gln Pro Pro Gly Ser Ala Ser Thr Asn Val Val Leu 
            100                 105                 110         


Arg His Asp Gly Ala Val Arg Trp Asp Ala Pro Ala Ile Thr Arg Ser 
        115                 120                 125             


Ser Cys Arg Val Asp Val Ala Ala Phe Pro Phe Asp Ala Gln His Cys 
    130                 135                 140                 


Gly Leu Thr Phe Gly Ser Trp Thr His Gly Gly His Gln Leu Asp Val 
145                 150                 155                 160 


Arg Pro Arg Gly Ala Ala Ala Ser Leu Ala Asp Phe Val Glu Asn Val 
                165                 170                 175     


Glu Trp Arg Val Leu Gly Met Pro Ala Arg Arg Arg Val Leu Thr Tyr 
            180                 185                 190         


Gly Cys Cys Ser Glu Pro Tyr Pro Asp Val Thr Phe Thr Leu Leu Leu 
        195                 200                 205             


Arg Arg Arg Ala Ala 
    210             


<210>  2898
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  2898

Glu Asp Ala Ser Ser Asp Ser Thr Gly Ala Asp Pro Ala Gln Glu Ala 
1               5                   10                  15      


Gly Thr Ser Lys Pro Asn Glu Glu Ile Ser Gly Pro Ala Glu Pro Ala 
            20                  25                  30          


Ser Pro Pro Glu Thr Thr Thr Thr Ala Gln Glu Thr Ser Ala Ala Ala 
        35                  40                  45              


Val Gln Gly Thr Ala Lys Val Thr Ser Ser Arg Gln Glu Leu Asn Pro 
    50                  55                  60                  


Leu Lys Ser Ile Val Glu Lys Ser Ile Leu Leu Thr Glu Gln Ala Leu 
65                  70                  75                  80  


Ala Lys Ala Gly Lys Gly Met His Gly Gly Val Pro Gly Gly Lys Gln 
                85                  90                  95      


Phe Ile Glu Asn Gly Ser Glu Phe Ala Gln Lys Leu Leu Lys Lys Phe 
            100                 105                 110         


Ser Leu Leu Lys Pro Trp Ala 
        115                 


<210>  2899
<211>  100
<212>  PRT
<213>  Homo Sapiens

<400>  2899

Leu Ala Gly Thr Pro Glu His Arg Cys Arg Val Pro Asp Ala Ala Asn 
1               5                   10                  15      


Leu Ser Ser Ala Trp Arg Asn Asn Ser Val Pro Leu Arg Leu Arg Asp 
            20                  25                  30          


Gly Arg Glu Val Pro His Ser Cys Ser Arg Tyr Arg Leu Ala Thr Ile 
        35                  40                  45              


Ala Asn Phe Ser Ala Leu Gly Leu Glu Pro Gly Arg Asp Val Asp Leu 
    50                  55                  60                  


Gly Gln Leu Glu Gln Glu Ser Cys Leu Asp Gly Trp Glu Phe Ser Gln 
65                  70                  75                  80  


Asp Val Tyr Leu Ser Thr Val Val Thr Glu Trp Asn Leu Val Cys Glu 
                85                  90                  95      


Asp Asn Trp Lys 
            100 


<210>  2900
<211>  475
<212>  PRT
<213>  Homo Sapiens

<400>  2900

Tyr Leu Leu Pro Asn Val Thr Leu Leu Glu Glu Leu Leu Ser Lys Tyr 
1               5                   10                  15      


Gln His Asn Glu Ser His Ser Arg Val Arg Arg Ala Ile Pro Arg Glu 
            20                  25                  30          


Asp Lys Glu Glu Ile Leu Met Leu His Asn Lys Leu Arg Gly Gln Val 
        35                  40                  45              


Gln Pro Gln Ala Ser Asn Met Glu Tyr Met Thr Trp Asp Asp Glu Leu 
    50                  55                  60                  


Glu Lys Ser Ala Ala Ala Trp Ala Ser Gln Cys Ile Trp Glu His Gly 
65                  70                  75                  80  


Pro Thr Ser Leu Leu Val Ser Ile Gly Gln Asn Leu Gly Ala His Trp 
                85                  90                  95      


Gly Arg Tyr Arg Ser Pro Gly Phe His Val Gln Ser Trp Tyr Asp Glu 
            100                 105                 110         


Val Lys Asp Tyr Thr Tyr Pro Tyr Pro Ser Glu Cys Asn Pro Trp Cys 
        115                 120                 125             


Pro Glu Arg Cys Ser Gly Pro Met Cys Thr His Tyr Thr Gln Ile Val 
    130                 135                 140                 


Trp Ala Thr Thr Asn Lys Ile Gly Cys Ala Val Asn Thr Cys Arg Lys 
145                 150                 155                 160 


Met Thr Val Trp Gly Glu Val Trp Glu Asn Ala Val Tyr Phe Val Cys 
                165                 170                 175     


Asn Tyr Ser Pro Lys Gly Asn Trp Ile Gly Glu Ala Pro Tyr Lys Asn 
            180                 185                 190         


Gly Arg Pro Cys Ser Glu Cys Pro Pro Ser Tyr Gly Gly Ser Cys Arg 
        195                 200                 205             


Asn Asn Leu Cys Tyr Arg Glu Glu Thr Tyr Thr Pro Lys Pro Glu Thr 
    210                 215                 220                 


Asp Glu Met Asn Glu Val Glu Thr Ala Pro Ile Pro Glu Glu Asn His 
225                 230                 235                 240 


Val Trp Leu Gln Pro Arg Val Met Arg Pro Thr Lys Pro Lys Lys Thr 
                245                 250                 255     


Ser Ala Val Asn Tyr Met Thr Gln Val Val Arg Cys Asp Thr Lys Met 
            260                 265                 270         


Lys Asp Arg Cys Lys Gly Ser Thr Cys Asn Arg Tyr Gln Cys Pro Ala 
        275                 280                 285             


Gly Cys Leu Asn His Lys Ala Lys Ile Phe Gly Thr Leu Phe Tyr Glu 
    290                 295                 300                 


Ser Ser Ser Ser Ile Cys Arg Ala Ala Ile His Tyr Gly Ile Leu Asp 
305                 310                 315                 320 


Asp Lys Gly Gly Leu Val Asp Ile Thr Arg Asn Gly Lys Val Pro Phe 
                325                 330                 335     


Phe Val Lys Ser Glu Arg His Gly Val Gln Ser Leu Ser Lys Tyr Lys 
            340                 345                 350         


Pro Ser Ser Ser Phe Met Val Ser Lys Val Lys Val Gln Asp Leu Asp 
        355                 360                 365             


Cys Tyr Thr Thr Val Ala Gln Leu Cys Pro Phe Glu Lys Pro Ala Thr 
    370                 375                 380                 


His Cys Pro Arg Ile His Cys Pro Ala His Cys Lys Asp Glu Pro Ser 
385                 390                 395                 400 


Tyr Trp Ala Pro Val Phe Gly Thr Asn Ile Tyr Ala Asp Thr Ser Ser 
                405                 410                 415     


Ile Cys Lys Thr Ala Val His Ala Gly Val Ile Ser Asn Glu Ser Gly 
            420                 425                 430         


Gly Asp Val Asp Val Met Pro Val Asp Lys Lys Lys Thr Tyr Val Gly 
        435                 440                 445             


Ser Leu Arg Asn Gly Val Gln Ser Glu Ser Leu Gly Thr Pro Arg Asp 
    450                 455                 460                 


Gly Lys Ala Phe Arg Ile Phe Ala Val Arg Gln 
465                 470                 475 


<210>  2901
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  2901

Gln Arg Lys Lys Glu Met Val Leu Ser Glu Lys Val Ser Gln Leu Met 
1               5                   10                  15      


Glu Trp Thr Asn Lys Arg Pro Val Ile Arg Met Asn Gly Asp Lys Phe 
            20                  25                  30          


Arg Arg Leu Val Lys Ala Pro Pro Arg Asn Tyr Ser Val Ile Val Met 
        35                  40                  45              


Phe Thr Ala Leu Gln Leu His Arg Gln Cys Val Val Cys Lys Gln Ala 
    50                  55                  60                  


Asp Glu Glu Phe Gln Ile Leu Ala Asn Ser Trp Arg Tyr Ser Ser Ala 
65                  70                  75                  80  


Phe Thr Asn Arg Ile Phe Phe Ala Met Val Asp Phe Asp Glu Gly Ser 
                85                  90                  95      


Asp Val Phe Gln Met Leu Asn Met Asn Ser Ala Pro Thr Phe Ile Asn 
            100                 105                 110         


Phe Pro Ala Lys Gly Lys Pro Lys Arg Gly Asp Thr Tyr Glu Leu Gln 
        115                 120                 125             


Val Arg Gly Phe Ser Ala Glu Gln Ile Ala Arg Trp Ile Ala Asp Arg 
    130                 135                 140                 


Thr Asp Val Asn Ile Arg Val Ile Arg Pro Pro 
145                 150                 155 


<210>  2902
<211>  482
<212>  PRT
<213>  Homo Sapiens

<400>  2902

Pro Cys Pro Asp Arg Pro Ala Ser Gln Arg Met Trp Arg Ile Asp Tyr 
1               5                   10                  15      


Ser Ala Ala Val Ile Tyr Asp Phe Leu Ala Val Asp Asp Ile Asn Gly 
            20                  25                  30          


Asp Arg Ile Gln Asp Val Leu Phe Leu Tyr Lys Asn Thr Asn Ser Ser 
        35                  40                  45              


Asn Asn Phe Ser Arg Ser Cys Val Asp Glu Gly Phe Ser Ser Pro Cys 
    50                  55                  60                  


Thr Phe Ala Ala Ala Val Ser Gly Ala Asn Gly Ser Thr Leu Trp Glu 
65                  70                  75                  80  


Arg Pro Val Ala Gln Asp Val Ala Leu Val Glu Cys Ala Val Pro Gln 
                85                  90                  95      


Pro Arg Gly Ser Glu Ala Pro Ser Ala Cys Ile Leu Val Gly Arg Pro 
            100                 105                 110         


Ser Ser Phe Ile Ala Val Asn Leu Phe Thr Gly Glu Thr Leu Trp Asn 
        115                 120                 125             


His Ser Ser Ser Phe Ser Gly Asn Ala Ser Ile Leu Ser Pro Leu Leu 
    130                 135                 140                 


Gln Val Pro Asp Val Asp Gly Asp Gly Ala Pro Asp Leu Leu Val Leu 
145                 150                 155                 160 


Thr Gln Glu Arg Glu Glu Val Ser Gly His Leu Tyr Ser Gly Ser Thr 
                165                 170                 175     


Gly His Gln Ile Gly Leu Arg Gly Ser Leu Gly Val Asp Gly Glu Ser 
            180                 185                 190         


Gly Phe Leu Leu His Val Thr Arg Thr Gly Ala His Tyr Ile Leu Phe 
        195                 200                 205             


Pro Cys Ala Ser Ser Leu Cys Gly Cys Ser Val Lys Gly Leu Tyr Glu 
    210                 215                 220                 


Lys Val Thr Gly Ser Gly Gly Pro Phe Lys Ser Asp Pro His Trp Glu 
225                 230                 235                 240 


Ser Met Leu Asn Ala Thr Thr Arg Arg Met Leu Ser His Ser Ser Gly 
                245                 250                 255     


Ala Val Arg Tyr Leu Met His Val Pro Gly Asn Ala Gly Ala Asp Val 
            260                 265                 270         


Leu Leu Val Gly Ser Glu Ala Phe Val Leu Leu Asp Gly Gln Glu Leu 
        275                 280                 285             


Thr Pro Arg Trp Thr Pro Lys Ala Ala His Val Leu Arg Lys Pro Ile 
    290                 295                 300                 


Phe Gly Arg Tyr Lys Pro Asp Thr Leu Ala Val Ala Val Glu Asn Gly 
305                 310                 315                 320 


Thr Gly Thr Asp Arg Gln Ile Leu Phe Leu Asp Leu Gly Thr Gly Ala 
                325                 330                 335     


Val Leu Cys Ser Leu Ala Leu Pro Ser Leu Pro Gly Gly Pro Leu Ser 
            340                 345                 350         


Ala Ser Leu Pro Thr Ala Asp His Arg Ser Ala Phe Phe Phe Trp Gly 
        355                 360                 365             


Leu His Glu Leu Gly Ser Thr Ser Glu Thr Glu Thr Gly Glu Ala Arg 
    370                 375                 380                 


His Ser Leu Tyr Met Phe His Pro Thr Leu Pro Arg Val Leu Leu Glu 
385                 390                 395                 400 


Leu Ala Asn Val Ser Thr His Ile Val Ala Phe Asp Ala Val Leu Phe 
                405                 410                 415     


Glu Pro Ser Arg His Ala Ala Tyr Ile Leu Leu Thr Gly Pro Ala Asp 
            420                 425                 430         


Ser Glu Ala Pro Gly Leu Val Ser Val Ile Lys His Lys Val Arg Asp 
        435                 440                 445             


Leu Val Pro Ser Ser Arg Val Val Arg Leu Gly Glu Gly Gly Pro Asp 
    450                 455                 460                 


Ser Asp Gln Ala Ile Arg Asp Arg Phe Ser Arg Leu Arg Tyr Gln Ser 
465                 470                 475                 480 


Glu Ala 
        


<210>  2903
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  2903

Arg Lys Lys Thr Phe Leu Ser Val His Glu Val Met Ala Val Glu Asn 
1               5                   10                  15      


Tyr Ala Lys Asp Ser Leu Gln Trp Ile Thr Asp Gln Tyr Asn Lys Glu 
            20                  25                  30          


Ser Asp Asp Lys Tyr His Phe Arg Ile Phe Arg Val Leu Lys Val Gln 
        35                  40                  45              


Arg Gln Val Thr Asp His Leu Glu Tyr His Leu Asn Val Glu Met Gln 
    50                  55                  60                  


Trp Thr Thr Cys Gln Lys Pro Glu Thr Thr Asn Cys Val Pro Gln Glu 
65                  70                  75                  80  


Arg Glu Leu His Lys Gln Val Asn Cys Phe Phe Ser Val Phe Ala Val 
                85                  90                  95      


Pro Trp Phe Glu Gln Tyr Lys Ile Leu Asn Lys Ser Cys Ser Ser Asp 
            100                 105                 110         


<210>  2904
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  2904

Ala Lys Leu Gly His Phe Gln Arg Trp Glu Gly Phe Gln Gln Lys Leu 
1               5                   10                  15      


Met Ser Lys Lys Asn Met Asn Ser Thr Leu Asn Phe Phe Ile Gln Ser 
            20                  25                  30          


Tyr Asn Asn Ala Ser Asn Asp Thr Tyr Leu Tyr Arg Val Gln Arg Leu 
        35                  40                  45              


Ile Arg Ser Gln Met Gln Leu Thr Thr Gly Val Glu Tyr Ile Val Thr 
    50                  55                  60                  


Val Lys Ile Gly Arg Thr Lys Cys Lys Arg Asn Asp Thr Ser Asn Ser 
65                  70                  75                  80  


Ser Cys Pro Leu Gln Ser Lys Lys Leu Arg Lys Ser Leu Ile Cys Glu 
                85                  90                  95      


Ser Leu Ile Tyr Thr Met Pro Trp Ile Asn Tyr Phe Gln Leu Trp Asn 
            100                 105                 110         


Asn Ser Cys Leu Glu Ala Glu His Val Gly Arg Asn Leu Arg 
        115                 120                 125     


<210>  2905
<211>  430
<212>  PRT
<213>  Homo Sapiens

<400>  2905

His Gln Asn Leu Lys Glu Phe Ala Leu Thr Asn Pro Glu Lys Ser Ser 
1               5                   10                  15      


Thr Lys Glu Thr Glu Arg Lys Glu Thr Lys Ala Glu Glu Glu Leu Asp 
            20                  25                  30          


Ala Glu Val Leu Glu Val Phe His Pro Thr His Glu Trp Gln Ala Leu 
        35                  40                  45              


Gln Pro Gly Gln Ala Val Pro Ala Gly Ser His Val Arg Leu Asn Leu 
    50                  55                  60                  


Gln Thr Gly Glu Arg Glu Ala Lys Leu Gln Tyr Glu Asp Lys Phe Arg 
65                  70                  75                  80  


Asn Asn Leu Lys Gly Lys Arg Leu Asp Ile Asn Thr Asn Thr Tyr Thr 
                85                  90                  95      


Ser Gln Asp Leu Lys Ser Ala Leu Ala Lys Phe Lys Glu Gly Ala Glu 
            100                 105                 110         


Met Glu Ser Ser Lys Glu Asp Lys Ala Arg Gln Ala Glu Val Lys Arg 
        115                 120                 125             


Leu Phe Arg Pro Ile Glu Glu Leu Lys Lys Asp Phe Asp Glu Leu Asn 
    130                 135                 140                 


Val Val Ile Glu Thr Asp Met Gln Ile Met Val Arg Leu Ile Asn Lys 
145                 150                 155                 160 


Phe Asn Ser Ser Ser Ser Ser Leu Glu Glu Lys Ile Ala Ala Leu Phe 
                165                 170                 175     


Asp Leu Glu Tyr Tyr Val His Gln Met Asp Asn Ala Gln Asp Leu Leu 
            180                 185                 190         


Ser Phe Gly Gly Leu Gln Val Val Ile Asn Gly Leu Asn Ser Thr Glu 
        195                 200                 205             


Pro Leu Val Lys Glu Tyr Ala Ala Phe Val Leu Gly Ala Ala Phe Ser 
    210                 215                 220                 


Ser Asn Pro Lys Val Gln Val Glu Ala Ile Glu Gly Gly Ala Leu Gln 
225                 230                 235                 240 


Lys Leu Leu Val Ile Leu Ala Thr Glu Gln Pro Leu Thr Ala Lys Lys 
                245                 250                 255     


Lys Val Leu Phe Ala Leu Cys Ser Leu Leu Arg His Phe Pro Tyr Ala 
            260                 265                 270         


Gln Arg Gln Phe Leu Lys Leu Gly Gly Leu Gln Val Leu Arg Thr Leu 
        275                 280                 285             


Val Gln Glu Lys Gly Thr Glu Val Leu Ala Val Arg Val Val Thr Leu 
    290                 295                 300                 


Leu Tyr Asp Leu Val Thr Glu Lys Met Phe Ala Glu Glu Glu Ala Glu 
305                 310                 315                 320 


Leu Thr Gln Glu Met Ser Pro Glu Lys Leu Gln Gln Tyr Arg Gln Val 
                325                 330                 335     


His Leu Leu Pro Gly Leu Trp Glu Gln Gly Trp Cys Glu Ile Thr Ala 
            340                 345                 350         


His Leu Leu Ala Leu Pro Glu His Asp Ala Arg Glu Lys Val Leu Gln 
        355                 360                 365             


Thr Leu Gly Val Leu Leu Thr Thr Cys Arg Asp Arg Tyr Arg Gln Asp 
    370                 375                 380                 


Pro Gln Leu Gly Arg Thr Leu Ala Ser Leu Gln Ala Glu Tyr Gln Val 
385                 390                 395                 400 


Leu Ala Ser Leu Glu Leu Gln Asp Gly Glu Asp Glu Gly Tyr Phe Gln 
                405                 410                 415     


Glu Leu Leu Gly Ser Val Asn Ser Leu Leu Lys Glu Leu Arg 
            420                 425                 430 


<210>  2906
<211>  300
<212>  PRT
<213>  Homo Sapiens

<400>  2906

Arg Arg Met Trp Thr Leu Arg Ser Pro Leu Thr Arg Ser Leu Tyr Val 
1               5                   10                  15      


Asn Met Thr Ser Gly Pro Gly Gly Pro Ala Ala Ala Ala Gly Gly Arg 
            20                  25                  30          


Lys Glu Asn His Gln Trp Tyr Val Cys Asn Arg Glu Lys Leu Cys Glu 
        35                  40                  45              


Ser Leu Gln Ala Val Phe Val Gln Ser Tyr Leu Asp Gln Gly Thr Gln 
    50                  55                  60                  


Ile Phe Leu Asn Asn Ser Ile Glu Lys Ser Gly Trp Leu Phe Ile Gln 
65                  70                  75                  80  


Leu Tyr His Ser Phe Val Ser Ser Val Phe Ser Leu Phe Met Ser Arg 
                85                  90                  95      


Thr Ser Ile Asn Gly Leu Leu Gly Arg Gly Ser Met Phe Val Phe Ser 
            100                 105                 110         


Pro Asp Gln Phe Gln Arg Leu Leu Lys Ile Asn Pro Asp Trp Lys Thr 
        115                 120                 125             


His Arg Leu Leu Asp Leu Gly Ala Gly Asp Gly Glu Val Thr Lys Ile 
    130                 135                 140                 


Met Ser Pro His Phe Glu Glu Ile Tyr Ala Thr Glu Leu Ser Glu Thr 
145                 150                 155                 160 


Met Ile Trp Gln Leu Gln Lys Lys Lys Tyr Arg Val Leu Gly Ile Asn 
                165                 170                 175     


Glu Trp Gln Asn Thr Gly Phe Gln Tyr Asp Val Ile Ser Cys Leu Asn 
            180                 185                 190         


Leu Leu Asp Arg Cys Asp Gln Pro Leu Thr Leu Leu Lys Asp Ile Arg 
        195                 200                 205             


Ser Val Leu Glu Pro Thr Arg Gly Arg Val Ile Leu Ala Leu Val Leu 
    210                 215                 220                 


Pro Phe His Pro Tyr Val Glu Asn Val Gly Gly Lys Trp Glu Lys Pro 
225                 230                 235                 240 


Ser Glu Ile Leu Glu Ile Lys Gly Gln Asn Trp Glu Glu Gln Val Asn 
                245                 250                 255     


Ser Leu Pro Glu Val Phe Arg Lys Ala Gly Phe Val Ile Glu Ala Phe 
            260                 265                 270         


Thr Arg Leu Pro Tyr Leu Cys Glu Gly Asp Met Tyr Asn Asp Tyr Tyr 
        275                 280                 285             


Val Leu Asp Asp Ala Val Phe Val Leu Lys Pro Val 
    290                 295                 300 


<210>  2907
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  2907

Lys Pro Lys Gly Met Thr Ser Ser Gln Trp Phe Lys Ile Gln His Met 
1               5                   10                  15      


Gln Pro Ser Pro Gln Ala Cys Asn Ser Ala Met Lys Asn Ile Asn Lys 
            20                  25                  30          


His Thr Lys Arg Cys Lys Asp Leu Asn Thr Phe Leu His Glu Pro Phe 
        35                  40                  45              


Ser Ser Val Ala Ala Thr Cys Gln Thr Pro Lys Ile Ala Cys Lys Asn 
    50                  55                  60                  


Gly Asp Lys Asn Cys His Gln Ser His Gly Pro Val Ser Leu Thr Met 
65                  70                  75                  80  


Cys Lys Leu Thr Ser Gly Lys Tyr Pro Asn Cys Arg Tyr Lys Glu Lys 
                85                  90                  95      


Arg Gln Asn Lys Ser Tyr Val Val Ala Cys Lys Pro Pro Gln Lys Lys 
            100                 105                 110         


Asp Ser Gln Gln Phe His Leu Val Pro Val His Leu Asp Arg Val Leu 
        115                 120                 125             


<210>  2908
<211>  58
<212>  PRT
<213>  Homo Sapiens

<400>  2908

Gly Tyr Arg Asp Lys Lys Arg Met Gln Lys Thr Gln Leu Ser Pro Glu 
1               5                   10                  15      


Ile Lys Val Cys Gln Gln Gln Pro Lys Leu Tyr Leu Cys Lys His Leu 
            20                  25                  30          


Cys Glu Ser His Arg Asp Cys Gln Ala Asn Asn Ile Cys Cys Ser Thr 
        35                  40                  45              


Tyr Cys Gly Asn Val Cys Met Ser Ile Leu 
    50                  55              


<210>  2909
<211>  342
<212>  PRT
<213>  Homo Sapiens

<400>  2909

Gln Leu Leu Thr Asp Ala Asn Ser Trp Trp Ser Leu Ala Leu Asn Pro 
1               5                   10                  15      


Val Gln Arg Pro Glu Met Phe Ile Ile Gly Ala Gln Pro Val Cys Ser 
            20                  25                  30          


Gln Leu Pro Gly Leu Ser Pro Gly Gln Arg Lys Leu Cys Gln Leu Tyr 
        35                  40                  45              


Gln Glu His Met Ala Tyr Ile Gly Glu Gly Ala Lys Thr Gly Ile Lys 
    50                  55                  60                  


Glu Cys Gln His Gln Phe Arg Gln Arg Arg Trp Asn Cys Ser Thr Ala 
65                  70                  75                  80  


Asp Asn Ala Ser Val Phe Gly Arg Val Met Gln Ile Gly Ser Arg Glu 
                85                  90                  95      


Thr Ala Phe Thr His Ala Val Ser Ala Ala Gly Val Val Asn Ala Ile 
            100                 105                 110         


Ser Arg Ala Cys Arg Glu Gly Glu Leu Ser Thr Cys Gly Cys Ser Arg 
        115                 120                 125             


Thr Ala Arg Pro Lys Asp Leu Pro Arg Asp Trp Leu Trp Gly Gly Cys 
    130                 135                 140                 


Gly Asp Asn Val Glu Tyr Gly Tyr Arg Phe Ala Lys Glu Phe Val Asp 
145                 150                 155                 160 


Ala Arg Glu Arg Glu Lys Asn Phe Ala Lys Gly Ser Glu Glu Gln Gly 
                165                 170                 175     


Arg Val Leu Met Asn Leu Gln Asn Asn Glu Ala Gly Arg Arg Ala Val 
            180                 185                 190         


Tyr Lys Met Ala Asp Val Ala Cys Lys Cys His Gly Val Ser Gly Ser 
        195                 200                 205             


Cys Ser Leu Lys Thr Cys Trp Leu Gln Leu Ala Glu Phe Arg Lys Val 
    210                 215                 220                 


Gly Asp Arg Leu Lys Glu Lys Tyr Asp Ser Ala Ala Ala Met Arg Val 
225                 230                 235                 240 


Thr Arg Lys Gly Arg Leu Glu Leu Val Asn Ser Arg Phe Thr Gln Pro 
                245                 250                 255     


Thr Pro Glu Asp Leu Val Tyr Val Asp Pro Ser Pro Asp Tyr Cys Leu 
            260                 265                 270         


Arg Asn Glu Ser Thr Gly Ser Leu Gly Thr Gln Gly Arg Leu Cys Asn 
        275                 280                 285             


Lys Thr Ser Glu Gly Met Asp Gly Cys Glu Leu Met Cys Cys Gly Arg 
    290                 295                 300                 


Gly Tyr Asn Gln Phe Lys Ser Val Gln Val Glu Arg Cys His Cys Lys 
305                 310                 315                 320 


Phe His Trp Cys Cys Phe Val Arg Cys Lys Lys Cys Thr Glu Ile Val 
                325                 330                 335     


Asp Gln Tyr Ile Cys Lys 
            340         


<210>  2910
<211>  164
<212>  PRT
<213>  Homo Sapiens

<400>  2910

Glu Phe Ile Gly Leu Arg Arg Cys Leu Met Gly Leu Gly Arg Cys Arg 
1               5                   10                  15      


Asp His Cys Asn Val Asp Glu Lys Glu Ile Gln Lys Cys Lys Met Lys 
            20                  25                  30          


Lys Cys Cys Val Gly Pro Lys Val Val Lys Leu Ile Lys Asn Tyr Leu 
        35                  40                  45              


Gln Tyr Gly Thr Pro Asn Val Leu Asn Glu Asp Val Gln Glu Met Leu 
    50                  55                  60                  


Lys Pro Ala Lys Asn Ser Ser Ala Val Ile Gln Arg Lys His Ile Leu 
65                  70                  75                  80  


Ser Val Leu Pro Gln Ile Lys Ser Thr Ser Phe Phe Ala Asn Thr Asn 
                85                  90                  95      


Phe Val Ile Ile Pro Asn Ala Thr Pro Met Asn Ser Ala Thr Ile Ser 
            100                 105                 110         


Thr Met Thr Pro Gly Gln Ile Thr Tyr Thr Ala Thr Ser Thr Lys Ser 
        115                 120                 125             


Asn Thr Lys Glu Ser Arg Asp Ser Ala Thr Ala Ser Pro Pro Pro Ala 
    130                 135                 140                 


Pro Pro Pro Pro Asn Ile Leu Pro Thr Pro Ser Leu Glu Leu Glu Glu 
145                 150                 155                 160 


Ala Glu Glu Gln 
                


<210>  2911
<211>  64
<212>  PRT
<213>  Homo Sapiens

<400>  2911

Lys Arg Gln Leu Trp Asp Arg Thr Arg Pro Glu Val Gln Gln Trp Tyr 
1               5                   10                  15      


Gln Gln Phe Leu Tyr Met Gly Phe Asp Glu Ala Lys Phe Glu Asp Asp 
            20                  25                  30          


Ile Thr Tyr Trp Leu Asn Arg Asp Arg Asn Gly His Glu Tyr Tyr Gly 
        35                  40                  45              


Asp Tyr Tyr Gln Arg His Tyr Asp Glu Asp Ser Ala Ile Gly Pro Arg 
    50                  55                  60                  


<210>  2912
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  2912

Met Ile Asn Leu Ser Ser Leu Trp Thr Val Pro Ala Trp Ile Ser Lys 
1               5                   10                  15      


Val Ser Phe Leu Arg Trp Cys Phe Glu Gly Leu Met Lys Ile Gln Phe 
            20                  25                  30          


Ser Arg Arg Thr Tyr Lys Met Pro Leu Gly Asn Leu Thr Ile Ala Val 
        35                  40                  45              


Ser Gly Asp Lys Ile Leu Ser Ala Met Glu Leu Asp Ser Tyr Pro 
    50                  55                  60              


<210>  2913
<211>  96
<212>  PRT
<213>  Homo Sapiens

<400>  2913

Gly Phe Lys Ala Asn Val Ile Asn Glu Lys Cys Ile Thr Gln Asn Ser 
1               5                   10                  15      


Glu Thr Ile Met Lys Phe Leu Lys Met Gly Asn Ile Ser Gln Asp Ile 
            20                  25                  30          


Ile Pro His His Ile Asn Leu Ser Thr Val Thr Ala Glu Asp Tyr His 
        35                  40                  45              


Leu Val Tyr Asp Ile Ile Gln Lys Val Lys Glu Glu Glu Phe Pro Ala 
    50                  55                  60                  


Leu His Leu Asn Ser Cys Lys Ile Glu Glu Glu Leu Asn Lys Ala Val 
65                  70                  75                  80  


Gln Gly Thr Gly Leu Ala Phe Ile Ala Phe Thr Glu Ala Met Thr His 
                85                  90                  95      


<210>  2914
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  2914

Leu Leu Glu Gly Asp Glu Cys Ala Pro His Ser Gln Pro Trp Gln Val 
1               5                   10                  15      


Ala Leu Tyr Glu Arg Gly Arg Phe Asn Cys Gly Ala Ser Leu Ile Ser 
            20                  25                  30          


Pro His Trp Val Leu Ser Ala Ala His Cys Gln Ser Arg Phe Met Arg 
        35                  40                  45              


Val Arg Leu Gly Glu His Asn Leu Arg Lys Arg Asp Gly Pro Glu Gln 
    50                  55                  60                  


Leu Arg Thr Thr Ser Arg Val Ile Pro His Pro Arg Tyr Glu Ala Arg 
65                  70                  75                  80  


Ser His Arg Asn Asp Ile Met Leu Leu Arg Leu Val Gln Pro Ala Arg 
                85                  90                  95      


Leu Asn Pro Gln Val Arg Pro Ala Val Leu Pro Thr Arg Cys Pro His 
            100                 105                 110         


Pro Gly Glu Ala Cys Val Val Ser Gly Trp Gly Leu Val Ser His Asn 
        115                 120                 125             


Glu Pro Gly Thr Ala Gly Ser Pro Arg Ser Gln Val Ser Leu Pro Asp 
    130                 135                 140                 


Thr Leu His Cys Ala Asn Ile Ser Ile Ile Ser Asp Thr Ser Cys Asp 
145                 150                 155                 160 


Lys Ser Tyr Pro Gly Arg Leu Thr Asn Thr Met Val Cys Ala Gly Ala 
                165                 170                 175     


Glu Gly Arg Gly Ala Glu Ser Cys Glu Gly Asp Ser Gly Gly Pro Leu 
            180                 185                 190         


Val Cys Gly Gly Ile Leu Gln Gly Ile Val Ser Trp Gly Asp Val Pro 
        195                 200                 205             


Cys Asp Asn Thr Thr Lys Pro Gly Val Tyr Thr Lys Val Cys His Tyr 
    210                 215                 220                 


Leu Glu Trp Ile Arg Glu Thr Met Lys Arg Asn 
225                 230                 235 


<210>  2915
<211>  492
<212>  PRT
<213>  Homo Sapiens

<400>  2915

Arg Lys Thr Val Pro Gly Asp Asn Glu Ser Glu Glu Asp Ser Lys Ile 
1               5                   10                  15      


Lys Gly Ile His Asp Glu Lys Tyr Val Glu Leu Phe Ile Val Ala Asp 
            20                  25                  30          


Asp Thr Val Tyr Arg Arg Asn Gly His Pro His Asn Lys Leu Arg Asn 
        35                  40                  45              


Arg Ile Trp Gly Met Val Asn Phe Val Asn Met Ile Tyr Lys Thr Leu 
    50                  55                  60                  


Asn Ile His Val Thr Leu Val Gly Ile Glu Ile Trp Thr His Glu Asp 
65                  70                  75                  80  


Lys Ile Glu Leu Tyr Ser Asn Ile Glu Thr Thr Leu Leu Arg Phe Ser 
                85                  90                  95      


Phe Trp Gln Glu Lys Ile Leu Lys Thr Arg Lys Asp Phe Asp His Val 
            100                 105                 110         


Val Leu Leu Ser Gly Lys Trp Leu Tyr Ser His Val Gln Gly Ile Ser 
        115                 120                 125             


Tyr Pro Gly Gly Met Cys Leu Pro Tyr Tyr Ser Thr Ser Ile Ile Lys 
    130                 135                 140                 


Asp Leu Leu Pro Asp Thr Asn Ile Ile Ala Asn Arg Met Ala His Gln 
145                 150                 155                 160 


Leu Gly His Asn Leu Gly Met Gln His Asp Glu Phe Pro Cys Thr Cys 
                165                 170                 175     


Pro Ser Gly Lys Cys Val Met Asp Ser Asp Gly Ser Ile Pro Ala Leu 
            180                 185                 190         


Lys Phe Ser Lys Cys Ser Gln Asn Gln Tyr His Gln Tyr Leu Lys Asp 
        195                 200                 205             


Tyr Lys Pro Thr Cys Met Leu Asn Ile Pro Phe Pro Tyr Asn Phe His 
    210                 215                 220                 


Asp Phe Gln Phe Cys Gly Asn Lys Lys Leu Asp Glu Gly Glu Glu Cys 
225                 230                 235                 240 


Asp Cys Gly Pro Ala Gln Glu Cys Thr Asn Pro Cys Cys Asp Ala His 
                245                 250                 255     


Thr Cys Val Leu Lys Pro Gly Phe Thr Cys Ala Glu Gly Glu Cys Cys 
            260                 265                 270         


Glu Ser Cys Gln Ile Lys Lys Ala Gly Ser Ile Cys Arg Pro Ala Lys 
        275                 280                 285             


Asp Glu Cys Asp Phe Pro Glu Met Cys Thr Gly His Ser Pro Ala Cys 
    290                 295                 300                 


Pro Lys Asp Gln Phe Arg Val Asn Gly Phe Pro Cys Lys Asn Ser Glu 
305                 310                 315                 320 


Gly Tyr Cys Phe Met Gly Lys Cys Pro Thr Arg Glu Asp Gln Cys Ser 
                325                 330                 335     


Glu Leu Phe Asp Asp Glu Ala Ile Glu Ser His Asp Ile Cys Tyr Lys 
            340                 345                 350         


Met Asn Thr Lys Gly Asn Lys Phe Gly Tyr Cys Lys Asn Lys Glu Asn 
        355                 360                 365             


Arg Phe Leu Pro Cys Glu Glu Lys Asp Val Arg Cys Gly Lys Ile Tyr 
    370                 375                 380                 


Cys Thr Gly Gly Glu Leu Ser Ser Leu Leu Gly Glu Asp Lys Thr Tyr 
385                 390                 395                 400 


His Leu Lys Asp Pro Gln Lys Asn Ala Thr Val Lys Cys Lys Thr Ile 
                405                 410                 415     


Phe Leu Tyr His Asp Ser Thr Asp Ile Gly Leu Val Ala Ser Gly Thr 
            420                 425                 430         


Lys Cys Gly Glu Gly Met Val Cys Asn Asn Gly Glu Cys Leu Asn Met 
        435                 440                 445             


Glu Lys Val Tyr Ile Ser Thr Asn Cys Pro Ser Gln Cys Asn Glu Asn 
    450                 455                 460                 


Pro Val Asp Gly His Gly Leu Gln Cys His Cys Glu Glu Gly Gln Ala 
465                 470                 475                 480 


Pro Val Ala Cys Glu Glu Thr Leu His Val Thr Asn 
                485                 490         


<210>  2916
<211>  415
<212>  PRT
<213>  Homo Sapiens

<400>  2916

Tyr Gly Tyr Thr Leu Pro Gly Trp Arg Lys Tyr Asn Leu Thr Tyr Arg 
1               5                   10                  15      


Ile Ile Asn Tyr Thr Pro Asp Met Ala Arg Ala Ala Val Asp Glu Ala 
            20                  25                  30          


Ile Gln Glu Gly Leu Glu Val Trp Ser Lys Val Thr Pro Leu Lys Phe 
        35                  40                  45              


Thr Lys Ile Ser Lys Gly Ile Ala Asp Ile Met Ile Ala Phe Arg Thr 
    50                  55                  60                  


Arg Val His Gly Arg Cys Pro Arg Tyr Phe Asp Gly Pro Leu Gly Val 
65                  70                  75                  80  


Leu Gly His Ala Phe Pro Pro Gly Pro Gly Leu Gly Gly Asp Thr His 
                85                  90                  95      


Phe Asp Glu Asp Glu Asn Trp Thr Lys Asp Gly Ala Gly Phe Asn Leu 
            100                 105                 110         


Phe Leu Val Ala Ala His Glu Phe Gly His Ala Leu Gly Leu Ser His 
        115                 120                 125             


Ser Asn Asp Gln Thr Ala Leu Met Phe Pro Asn Tyr Val Ser Leu Asp 
    130                 135                 140                 


Pro Arg Lys Tyr Pro Leu Ser Gln Asp Asp Ile Asn Gly Ile Gln Ser 
145                 150                 155                 160 


Ile Tyr Gly Gly Leu Pro Lys Glu Pro Ala Lys Pro Lys Glu Pro Thr 
                165                 170                 175     


Ile Pro His Ala Cys Asp Pro Asp Leu Thr Phe Asp Ala Ile Thr Thr 
            180                 185                 190         


Phe Arg Arg Glu Val Met Phe Phe Lys Gly Arg His Leu Trp Arg Ile 
        195                 200                 205             


Tyr Tyr Asp Ile Thr Asp Val Glu Phe Glu Leu Ile Ala Ser Phe Trp 
    210                 215                 220                 


Pro Ser Leu Pro Ala Asp Leu Gln Ala Ala Tyr Glu Asn Pro Arg Asp 
225                 230                 235                 240 


Lys Ile Leu Val Phe Lys Asp Glu Asn Phe Trp Met Ile Arg Gly Tyr 
                245                 250                 255     


Ala Val Leu Pro Asp Tyr Pro Lys Ser Ile His Thr Leu Gly Phe Pro 
            260                 265                 270         


Gly Arg Val Lys Lys Ile Asp Ala Ala Val Cys Asp Lys Thr Thr Arg 
        275                 280                 285             


Lys Thr Tyr Phe Phe Val Gly Ile Trp Cys Trp Arg Phe Asp Glu Met 
    290                 295                 300                 


Thr Gln Thr Met Asp Lys Gly Phe Pro Gln Arg Val Val Lys His Phe 
305                 310                 315                 320 


Pro Gly Ile Ser Ile Arg Val Asp Ala Ala Phe Gln Tyr Lys Gly Phe 
                325                 330                 335     


Phe Phe Phe Ser Arg Gly Ser Lys Gln Phe Glu Tyr Asp Ile Lys Thr 
            340                 345                 350         


Lys Asn Ile Thr Arg Ile Met Arg Thr Asn Thr Trp Phe Gln Cys Lys 
        355                 360                 365             


Glu Pro Lys Asn Ser Ser Phe Gly Phe Asp Ile Asn Lys Glu Lys Ala 
    370                 375                 380                 


His Ser Gly Gly Ile Lys Ile Leu Tyr His Lys Ser Leu Ser Leu Phe 
385                 390                 395                 400 


Ile Phe Gly Ile Val His Leu Leu Lys Asn Thr Ser Ile Tyr Gln 
                405                 410                 415 


<210>  2917
<211>  477
<212>  PRT
<213>  Homo Sapiens

<400>  2917

Met Val Val Pro Asn Ala Thr Leu Leu Glu Lys Leu Leu Glu Lys Tyr 
1               5                   10                  15      


Met Asp Glu Asp Gly Glu Trp Trp Ile Ala Lys Gln Arg Gly Lys Arg 
            20                  25                  30          


Ala Ile Thr Asp Asn Asp Met Gln Ser Ile Leu Asp Leu His Asn Lys 
        35                  40                  45              


Leu Arg Ser Gln Val Tyr Pro Thr Ala Ser Asn Met Glu Tyr Met Thr 
    50                  55                  60                  


Trp Asp Val Glu Leu Glu Arg Ser Ala Glu Ser Trp Ala Glu Ser Cys 
65                  70                  75                  80  


Leu Trp Glu His Gly Pro Ala Ser Leu Leu Pro Ser Ile Gly Gln Asn 
                85                  90                  95      


Leu Gly Ala His Trp Gly Arg Tyr Arg Pro Pro Thr Phe His Val Gln 
            100                 105                 110         


Ser Trp Tyr Asp Glu Val Lys Asp Phe Ser Tyr Pro Tyr Glu His Glu 
        115                 120                 125             


Cys Asn Pro Tyr Cys Pro Phe Arg Cys Ser Gly Pro Val Cys Thr His 
    130                 135                 140                 


Tyr Thr Gln Val Val Trp Ala Thr Ser Asn Arg Ile Gly Cys Ala Ile 
145                 150                 155                 160 


Asn Leu Cys His Asn Met Asn Ile Trp Gly Gln Ile Trp Pro Lys Ala 
                165                 170                 175     


Val Tyr Leu Val Cys Asn Tyr Ser Pro Lys Gly Asn Trp Trp Gly His 
            180                 185                 190         


Ala Pro Tyr Lys His Gly Arg Pro Cys Ser Ala Cys Pro Pro Ser Phe 
        195                 200                 205             


Gly Gly Gly Cys Arg Glu Asn Leu Cys Tyr Lys Glu Gly Ser Asp Arg 
    210                 215                 220                 


Tyr Tyr Pro Pro Arg Glu Glu Glu Thr Asn Glu Ile Glu Arg Gln Gln 
225                 230                 235                 240 


Ser Gln Val His Asp Thr His Val Arg Thr Arg Ser Asp Asp Ser Ser 
                245                 250                 255     


Arg Asn Glu Val Ile Ser Ala Gln Gln Met Ser Gln Ile Val Ser Cys 
            260                 265                 270         


Glu Val Arg Leu Arg Asp Gln Cys Lys Gly Thr Thr Cys Asn Arg Tyr 
        275                 280                 285             


Glu Cys Pro Ala Gly Cys Leu Asp Ser Lys Ala Lys Val Ile Gly Ser 
    290                 295                 300                 


Val His Tyr Glu Met Gln Ser Ser Ile Cys Arg Ala Ala Ile His Tyr 
305                 310                 315                 320 


Gly Ile Ile Asp Asn Asp Gly Gly Trp Val Asp Ile Thr Arg Gln Gly 
                325                 330                 335     


Arg Lys His Tyr Phe Ile Lys Ser Asn Arg Asn Gly Ile Gln Thr Ile 
            340                 345                 350         


Gly Lys Tyr Gln Ser Ala Asn Ser Phe Thr Val Ser Lys Val Thr Val 
        355                 360                 365             


Gln Ala Val Thr Cys Glu Thr Thr Val Glu Gln Leu Cys Pro Phe His 
    370                 375                 380                 


Lys Pro Ala Ser His Cys Pro Arg Val Tyr Cys Pro Arg Asn Cys Met 
385                 390                 395                 400 


Gln Ala Asn Pro His Tyr Ala Arg Val Ile Gly Thr Arg Val Tyr Ser 
                405                 410                 415     


Asp Leu Ser Ser Ile Cys Arg Ala Ala Val His Ala Gly Val Val Arg 
            420                 425                 430         


Asn His Gly Gly Tyr Val Asp Val Met Pro Val Asp Lys Arg Lys Thr 
        435                 440                 445             


Tyr Ile Ala Ser Phe Gln Asn Gly Ile Phe Ser Glu Ser Leu Gln Asn 
    450                 455                 460                 


Pro Pro Gly Gly Lys Ala Phe Arg Val Phe Ala Val Val 
465                 470                 475         


<210>  2918
<211>  454
<212>  PRT
<213>  Homo Sapiens

<400>  2918

Leu Phe Arg Ser Leu Tyr Arg Ser Val Ser Met Pro Pro Lys Gly Asp 
1               5                   10                  15      


Ser Gly Gln Pro Leu Phe Leu Thr Pro Tyr Ile Glu Ala Gly Lys Ile 
            20                  25                  30          


Gln Lys Gly Arg Glu Leu Ser Leu Val Gly Pro Phe Pro Gly Leu Asn 
        35                  40                  45              


Met Lys Ser Tyr Ala Gly Phe Leu Thr Val Asn Lys Thr Tyr Asn Ser 
    50                  55                  60                  


Asn Leu Phe Phe Trp Phe Phe Pro Ala Gln Ile Gln Pro Glu Asp Ala 
65                  70                  75                  80  


Pro Val Val Leu Trp Leu Gln Gly Gly Pro Gly Gly Ser Ser Met Phe 
                85                  90                  95      


Gly Leu Phe Val Glu His Gly Pro Tyr Val Val Thr Ser Asn Met Thr 
            100                 105                 110         


Leu Arg Asp Arg Asp Phe Pro Trp Thr Thr Thr Leu Ser Met Leu Tyr 
        115                 120                 125             


Ile Asp Asn Pro Val Gly Thr Gly Phe Ser Phe Thr Asp Asp Thr His 
    130                 135                 140                 


Gly Tyr Ala Val Asn Glu Asp Asp Val Ala Arg Asp Leu Tyr Ser Ala 
145                 150                 155                 160 


Leu Ile Gln Phe Phe Gln Ile Phe Pro Glu Tyr Lys Asn Asn Asp Phe 
                165                 170                 175     


Tyr Val Thr Gly Glu Ser Tyr Ala Gly Lys Tyr Val Pro Ala Ile Ala 
            180                 185                 190         


His Leu Ile His Ser Leu Asn Pro Val Arg Glu Val Lys Ile Asn Leu 
        195                 200                 205             


Asn Gly Ile Ala Ile Gly Asp Gly Tyr Ser Asp Pro Glu Ser Ile Ile 
    210                 215                 220                 


Gly Gly Tyr Ala Glu Phe Leu Tyr Gln Ile Gly Leu Leu Asp Glu Lys 
225                 230                 235                 240 


Gln Lys Lys Tyr Phe Gln Lys Gln Cys His Glu Cys Ile Glu His Ile 
                245                 250                 255     


Arg Lys Gln Asn Trp Phe Glu Ala Phe Glu Ile Leu Asp Lys Leu Leu 
            260                 265                 270         


Asp Gly Asp Leu Thr Ser Asp Pro Ser Tyr Phe Gln Asn Val Thr Gly 
        275                 280                 285             


Cys Ser Asn Tyr Tyr Asn Phe Leu Arg Cys Thr Glu Pro Glu Asp Gln 
    290                 295                 300                 


Leu Tyr Tyr Val Lys Phe Leu Ser Leu Pro Glu Val Arg Gln Ala Ile 
305                 310                 315                 320 


His Val Gly Asn Gln Thr Phe Asn Asp Gly Thr Ile Val Glu Lys Tyr 
                325                 330                 335     


Leu Arg Glu Asp Thr Val Gln Ser Val Lys Pro Trp Leu Thr Glu Ile 
            340                 345                 350         


Met Asn Asn Tyr Lys Val Leu Ile Tyr Asn Gly Gln Leu Asp Ile Ile 
        355                 360                 365             


Val Ala Ala Ala Leu Thr Glu Arg Ser Leu Met Gly Met Asp Trp Lys 
    370                 375                 380                 


Gly Ser Gln Glu Tyr Lys Lys Ala Glu Lys Lys Val Trp Lys Ile Phe 
385                 390                 395                 400 


Lys Ser Asp Ser Glu Val Ala Gly Tyr Ile Arg Gln Val Gly Asp Phe 
                405                 410                 415     


His Gln Val Ile Ile Arg Gly Gly Gly His Ile Leu Pro Tyr Asp Gln 
            420                 425                 430         


Pro Leu Arg Ala Phe Asp Met Ile Asn Arg Phe Ile Tyr Gly Lys Gly 
        435                 440                 445             


Trp Asp Pro Tyr Val Gly 
    450                 


<210>  2919
<211>  154
<212>  PRT
<213>  Homo Sapiens

<400>  2919

Arg Arg Ser Asn Val Arg Val Ile Thr Asp Glu Asn Trp Arg Glu Leu 
1               5                   10                  15      


Leu Glu Gly Asp Trp Met Ile Glu Phe Tyr Ala Pro Trp Cys Pro Ala 
            20                  25                  30          


Cys Gln Asn Leu Gln Pro Glu Trp Glu Ser Phe Ala Glu Trp Gly Glu 
        35                  40                  45              


Asp Leu Glu Val Asn Ile Ala Lys Val Asp Val Thr Glu Gln Pro Gly 
    50                  55                  60                  


Leu Ser Gly Arg Phe Ile Ile Thr Ala Leu Pro Thr Ile Tyr His Cys 
65                  70                  75                  80  


Lys Asp Gly Glu Phe Arg Arg Tyr Gln Gly Pro Arg Thr Lys Lys Asp 
                85                  90                  95      


Phe Ile Asn Phe Ile Ser Asp Lys Glu Trp Lys Ser Ile Glu Pro Val 
            100                 105                 110         


Ser Ser Trp Phe Gly Pro Gly Ser Val Leu Met Ser Ser Met Ser Ala 
        115                 120                 125             


Leu Phe Gln Leu Ser Met Trp Ile Arg Thr Cys His Asn Tyr Phe Ile 
    130                 135                 140                 


Glu Asp Leu Gly Leu Pro Val Trp Gly Ser 
145                 150                 


<210>  2920
<211>  387
<212>  PRT
<213>  Homo Sapiens

<400>  2920

Tyr Leu Cys Pro Ala Ala Ser Gln Pro Ile Ser Gly Thr Leu Gln Asp 
1               5                   10                  15      


Glu Glu Ile Thr Leu Ser Cys Ser Glu Ala Ser Ala Glu Glu Ala Leu 
            20                  25                  30          


Leu Pro Ala Leu Pro Lys Thr Val Ser Phe Arg Ile Asn Ser Glu Asp 
        35                  40                  45              


Phe Leu Leu Glu Ala Gln Val Arg Asp Gln Pro Arg Trp Leu Leu Val 
    50                  55                  60                  


Cys His Glu Gly Trp Ser Pro Ala Leu Gly Leu Gln Ile Cys Trp Ser 
65                  70                  75                  80  


Leu Gly His Leu Arg Leu Thr His His Lys Gly Val Asn Leu Thr Asp 
                85                  90                  95      


Ile Lys Leu Asn Ser Ser Gln Glu Phe Ala Gln Leu Ser Pro Arg Leu 
            100                 105                 110         


Gly Gly Phe Leu Glu Glu Ala Trp Gln Pro Arg Asn Asn Cys Thr Ser 
        115                 120                 125             


Gly Gln Val Val Ser Leu Arg Cys Ser Glu Cys Gly Ala Arg Pro Leu 
    130                 135                 140                 


Ala Ser Arg Ile Val Gly Gly Gln Ser Val Ala Pro Gly Arg Trp Pro 
145                 150                 155                 160 


Trp Gln Ala Ser Val Ala Leu Gly Phe Arg His Thr Cys Gly Gly Ser 
                165                 170                 175     


Val Leu Ala Pro Arg Trp Val Val Thr Ala Ala His Cys Met His Ser 
            180                 185                 190         


Phe Arg Leu Ala Arg Leu Ser Ser Trp Arg Val His Ala Gly Leu Val 
        195                 200                 205             


Ser His Ser Ala Val Arg Pro His Gln Gly Ala Leu Val Glu Arg Ile 
    210                 215                 220                 


Ile Pro His Pro Leu Tyr Ser Ala Gln Asn His Asp Tyr Asp Val Ala 
225                 230                 235                 240 


Leu Leu Arg Leu Gln Thr Ala Leu Asn Phe Ser Asp Thr Val Gly Ala 
                245                 250                 255     


Val Cys Leu Pro Ala Lys Glu Gln His Phe Pro Lys Gly Ser Arg Cys 
            260                 265                 270         


Trp Val Ser Gly Trp Gly His Thr His Pro Ser His Thr Tyr Ser Ser 
        275                 280                 285             


Asp Met Leu Gln Asp Thr Val Val Pro Leu Leu Ser Thr Gln Leu Cys 
    290                 295                 300                 


Asn Ser Ser Cys Val Tyr Ser Gly Ala Leu Thr Pro Arg Met Leu Cys 
305                 310                 315                 320 


Ala Gly Tyr Leu Asp Gly Arg Ala Asp Ala Cys Gln Gly Asp Ser Gly 
                325                 330                 335     


Gly Pro Leu Val Cys Pro Asp Gly Asp Thr Trp Arg Leu Val Gly Val 
            340                 345                 350         


Val Ser Trp Gly Arg Gly Cys Ala Glu Pro Asn His Pro Gly Val Tyr 
        355                 360                 365             


Ala Lys Val Ala Glu Phe Leu Asp Trp Ile His Asp Thr Ala Gln Asp 
    370                 375                 380                 


Ser Leu Leu 
385         


<210>  2921
<211>  425
<212>  PRT
<213>  Homo Sapiens

<400>  2921

Gln Lys Phe Ser Ala Leu Thr Phe Leu Arg Val Asp Gln Asp Lys Asp 
1               5                   10                  15      


Lys Asp Cys Ser Leu Asp Cys Ala Gly Ser Pro Gln Lys Pro Leu Cys 
            20                  25                  30          


Ala Ser Asp Gly Arg Thr Phe Leu Ser Arg Cys Glu Phe Gln Arg Ala 
        35                  40                  45              


Lys Cys Lys Asp Pro Gln Leu Glu Ile Ala Tyr Arg Gly Asn Cys Lys 
    50                  55                  60                  


Asp Val Ser Arg Cys Val Ala Glu Arg Lys Tyr Thr Gln Glu Gln Ala 
65                  70                  75                  80  


Arg Lys Glu Phe Gln Gln Val Phe Ile Pro Glu Cys Asn Asp Asp Gly 
                85                  90                  95      


Thr Tyr Ser Gln Val Gln Cys His Ser Tyr Thr Gly Tyr Cys Trp Cys 
            100                 105                 110         


Val Thr Pro Asn Gly Arg Pro Ile Ser Gly Thr Ala Val Ala His Lys 
        115                 120                 125             


Thr Pro Arg Cys Pro Gly Ser Val Asn Glu Lys Leu Pro Gln Arg Glu 
    130                 135                 140                 


Gly Thr Gly Lys Thr Asp Asp Ala Ala Ala Pro Ala Leu Glu Thr Gln 
145                 150                 155                 160 


Pro Gln Gly Asp Glu Glu Asp Ile Ala Ser Arg Tyr Pro Thr Leu Trp 
                165                 170                 175     


Thr Glu Gln Val Lys Ser Arg Gln Asn Lys Thr Asn Lys Asn Ser Val 
            180                 185                 190         


Ser Ser Cys Asp Gln Glu His Gln Ser Ala Leu Glu Glu Ala Lys Gln 
        195                 200                 205             


Pro Lys Asn Asp Asn Val Val Ile Pro Glu Cys Ala His Gly Gly Leu 
    210                 215                 220                 


Tyr Lys Pro Val Gln Cys His Pro Ser Thr Gly Tyr Cys Trp Cys Val 
225                 230                 235                 240 


Leu Val Asp Thr Gly Arg Pro Ile Pro Gly Thr Ser Thr Arg Tyr Glu 
                245                 250                 255     


Gln Pro Lys Cys Asp Asn Thr Ala Arg Ala His Pro Ala Lys Ala Arg 
            260                 265                 270         


Asp Leu Tyr Lys Gly Arg Gln Leu Gln Gly Cys Pro Gly Ala Lys Lys 
        275                 280                 285             


His Glu Phe Leu Thr Ser Val Leu Asp Ala Leu Ser Thr Asp Met Val 
    290                 295                 300                 


His Ala Ala Ser Asp Pro Ser Ser Ser Ser Gly Arg Leu Ser Glu Pro 
305                 310                 315                 320 


Asp Pro Ser His Thr Leu Glu Glu Arg Val Val His Trp Tyr Phe Lys 
                325                 330                 335     


Leu Leu Asp Lys Asn Ser Ser Gly Asp Ile Gly Lys Lys Glu Ile Lys 
            340                 345                 350         


Pro Phe Lys Arg Phe Leu Arg Lys Lys Ser Lys Pro Lys Lys Cys Val 
        355                 360                 365             


Lys Lys Phe Val Glu Tyr Cys Asp Val Asn Asn Asp Lys Ser Ile Ser 
    370                 375                 380                 


Val Gln Glu Leu Met Gly Cys Leu Gly Val Ala Lys Glu Asp Gly Lys 
385                 390                 395                 400 


Ala Asp Thr Lys Lys Arg His Thr Pro Arg Gly His Val Glu Ser Thr 
                405                 410                 415     


Ser Asn Arg Gln Pro Arg Lys Gln Gly 
            420                 425 


<210>  2922
<211>  197
<212>  PRT
<213>  Homo Sapiens

<400>  2922

His Ile Ser Val Arg Asp Met Asn Ala Leu Leu Asp Tyr His Asn His 
1               5                   10                  15      


Ile Arg Ala Ser Val Tyr Pro Pro Ala Ala Asn Met Glu Tyr Met Val 
            20                  25                  30          


Trp Asp Lys Arg Leu Ala Arg Ala Ala Glu Ala Trp Ala Thr Gln Cys 
        35                  40                  45              


Ile Trp Ala His Gly Pro Ser Gln Leu Met Arg Tyr Val Gly Gln Asn 
    50                  55                  60                  


Leu Ser Ile His Ser Gly Gln Tyr Arg Ser Val Val Asp Leu Met Lys 
65                  70                  75                  80  


Ser Trp Ser Glu Glu Lys Trp His Tyr Leu Phe Pro Ala Pro Arg Asp 
                85                  90                  95      


Cys Asn Pro His Cys Pro Trp Arg Cys Asp Gly Pro Thr Cys Ser His 
            100                 105                 110         


Tyr Thr Gln Met Val Trp Ala Ser Ser Asn Arg Leu Gly Cys Ala Ile 
        115                 120                 125             


His Thr Cys Ser Ser Ile Ser Val Trp Gly Asn Thr Trp His Arg Ala 
    130                 135                 140                 


Ala Tyr Leu Val Cys Asn Tyr Ala Ile Lys Gly Asn Trp Ile Gly Glu 
145                 150                 155                 160 


Ser Pro Tyr Lys Met Gly Lys Pro Cys Ser Ser Cys Pro Pro Ser Tyr 
                165                 170                 175     


Gln Gly Ser Cys Asn Ser Asn Met Cys Phe Lys Gly Leu Lys Ser Asn 
            180                 185                 190         


Lys Phe Thr Trp Phe 
        195         


<210>  2923
<211>  248
<212>  PRT
<213>  Homo Sapiens

<400>  2923

Ala Ser Ala Lys Glu Leu Ala Cys Gln Glu Ile Thr Val Pro Leu Cys 
1               5                   10                  15      


Lys Gly Ile Gly Tyr Asn Tyr Thr Tyr Met Pro Asn Gln Phe Asn His 
            20                  25                  30          


Asp Thr Gln Asp Glu Ala Gly Leu Glu Val His Gln Phe Trp Pro Leu 
        35                  40                  45              


Val Glu Ile Gln Cys Ser Pro Asp Leu Lys Phe Phe Leu Cys Ser Met 
    50                  55                  60                  


Tyr Thr Pro Ile Cys Leu Glu Asp Tyr Lys Lys Pro Leu Pro Pro Cys 
65                  70                  75                  80  


Arg Ser Val Cys Glu Arg Ala Lys Ala Gly Cys Ala Pro Leu Met Arg 
                85                  90                  95      


Gln Tyr Gly Phe Ala Trp Pro Asp Arg Met Arg Cys Asp Arg Leu Pro 
            100                 105                 110         


Glu Gln Gly Asn Pro Asp Thr Leu Cys Met Asp Tyr Asn Arg Thr Asp 
        115                 120                 125             


Leu Thr Thr Ala Ala Pro Ser Pro Pro Arg Arg Leu Pro Pro Pro Pro 
    130                 135                 140                 


Pro Gly Glu Gln Pro Pro Ser Gly Ser Gly His Gly Arg Pro Pro Gly 
145                 150                 155                 160 


Ala Arg Pro Pro His Arg Gly Gly Gly Arg Gly Gly Gly Gly Gly Asp 
                165                 170                 175     


Ala Ala Ala Pro Pro Ala Arg Gly Gly Gly Gly Gly Gly Lys Ala Arg 
            180                 185                 190         


Pro Pro Gly Gly Gly Ala Ala Pro Cys Glu Pro Gly Cys Gln Cys Arg 
        195                 200                 205             


Ala Pro Met Val Ser Val Ser Ser Glu Arg His Pro Leu Tyr Asn Arg 
    210                 215                 220                 


Val Lys Thr Gly Gln Ile Ala Asn Cys Ala Leu Pro Cys His Asn Pro 
225                 230                 235                 240 


Phe Phe Ser Gln Asp Glu Arg Ala 
                245             


<210>  2924
<211>  372
<212>  PRT
<213>  Homo Sapiens

<400>  2924

Ala Ser Arg Pro Trp Glu Gly Thr Asp Glu Pro Gly Ser Ala Trp Ala 
1               5                   10                  15      


Trp Pro Gly Phe Gln Arg Leu Gln Glu Gln Leu Arg Ala Ala Gly Ala 
            20                  25                  30          


Leu Ser Lys Arg Tyr Trp Thr Leu Phe Ser Cys Gln Val Trp Pro Asp 
        35                  40                  45              


Asp Cys Asp Glu Asp Glu Glu Ala Ala Thr Gly Pro Leu Gly Trp Arg 
    50                  55                  60                  


Leu Pro Leu Leu Gly Gln Arg Tyr Leu Asp Leu Leu Thr Thr Trp Tyr 
65                  70                  75                  80  


Cys Ser Phe Lys Asp Cys Cys Pro Arg Gly Asp Cys Arg Ile Ser Asn 
                85                  90                  95      


Asn Phe Thr Gly Leu Glu Trp Asp Leu Asn Val Arg Leu His Gly Gln 
            100                 105                 110         


His Leu Val Gln Gln Leu Val Leu Arg Thr Val Arg Gly Tyr Leu Glu 
        115                 120                 125             


Thr Pro Gln Pro Glu Lys Ala Leu Ala Leu Ser Phe His Gly Trp Ser 
    130                 135                 140                 


Gly Thr Gly Lys Asn Phe Val Ala Arg Met Leu Val Glu Asn Leu Tyr 
145                 150                 155                 160 


Arg Asp Gly Leu Met Ser Asp Cys Val Arg Met Phe Ile Ala Thr Phe 
                165                 170                 175     


His Phe Pro His Pro Lys Tyr Val Asp Leu Tyr Lys Glu Gln Leu Met 
            180                 185                 190         


Ser Gln Ile Arg Glu Thr Gln Gln Leu Cys His Gln Thr Leu Phe Ile 
        195                 200                 205             


Phe Asp Glu Ala Glu Lys Leu His Pro Gly Leu Leu Glu Val Leu Gly 
    210                 215                 220                 


Pro His Leu Glu Arg Arg Ala Pro Glu Gly His Arg Ala Glu Ser Pro 
225                 230                 235                 240 


Trp Thr Ile Phe Leu Phe Pro Ser Asn Leu Arg Gly Asp Ile Ile Asn 
                245                 250                 255     


Glu Val Val Leu Lys Leu Leu Lys Ala Gly Trp Ser Arg Glu Glu Ile 
            260                 265                 270         


Thr Met Glu His Leu Glu Pro His Leu Gln Ala Glu Ile Val Glu Thr 
        275                 280                 285             


Ile Asp Asn Gly Phe Gly His Ser Arg Leu Val Lys Glu Asn Leu Ile 
    290                 295                 300                 


Asp Tyr Phe Ile Pro Phe Leu Pro Leu Glu Tyr Arg His Val Arg Leu 
305                 310                 315                 320 


Cys Ala Arg Asp Ala Phe Leu Ser Gln Glu Leu Leu Tyr Lys Glu Glu 
                325                 330                 335     


Thr Leu Asp Glu Ile Ala Gln Met Met Val Tyr Val Pro Lys Glu Glu 
            340                 345                 350         


Gln Leu Phe Ser Ser Gln Gly Cys Lys Ser Ile Ser Gln Arg Ile Asn 
        355                 360                 365             


Tyr Phe Leu Ser 
    370         


<210>  2925
<211>  649
<212>  PRT
<213>  Homo Sapiens

<400>  2925

Ala Ser Gly Glu His Ser Pro Gly Ser Gly Ala Ala Arg Arg Pro Leu 
1               5                   10                  15      


His Ser Ala Gln Ala Val Asp Val Ala Ser Ala Ser Asn Phe Arg Ala 
            20                  25                  30          


Phe Glu Leu Leu His Leu His Leu Asp Leu Arg Ala Glu Phe Gly Pro 
        35                  40                  45              


Pro Gly Pro Gly Ala Gly Ser Arg Gly Leu Ser Gly Thr Ala Val Leu 
    50                  55                  60                  


Asp Leu Arg Cys Leu Glu Pro Glu Gly Ala Ala Glu Leu Arg Leu Asp 
65                  70                  75                  80  


Ser His Pro Cys Leu Glu Val Thr Ala Ala Ala Leu Arg Arg Glu Arg 
                85                  90                  95      


Pro Gly Ser Glu Glu Pro Pro Ala Glu Pro Val Ser Phe Tyr Thr Gln 
            100                 105                 110         


Pro Phe Ser His Tyr Gly Gln Ala Leu Cys Val Ser Phe Pro Gln Pro 
        115                 120                 125             


Cys Arg Ala Ala Glu Arg Leu Gln Val Leu Leu Thr Tyr Arg Val Gly 
    130                 135                 140                 


Glu Gly Pro Gly Val Cys Trp Leu Ala Pro Glu Gln Thr Ala Gly Lys 
145                 150                 155                 160 


Lys Lys Pro Phe Val Tyr Thr Gln Gly Gln Ala Val Leu Asn Arg Ala 
                165                 170                 175     


Phe Phe Pro Cys Phe Asp Thr Pro Ala Val Lys Tyr Lys Tyr Ser Ala 
            180                 185                 190         


Leu Ile Glu Val Pro Asp Gly Phe Thr Ala Val Met Ser Ala Ser Thr 
        195                 200                 205             


Trp Glu Lys Arg Gly Pro Asn Lys Phe Phe Phe Gln Met Cys Gln Pro 
    210                 215                 220                 


Ile Pro Ser Tyr Leu Ile Ala Leu Ala Ile Gly Asp Leu Val Ser Ala 
225                 230                 235                 240 


Glu Val Gly Pro Arg Ser Arg Val Trp Ala Glu Pro Cys Leu Ile Asp 
                245                 250                 255     


Ala Ala Lys Glu Glu Tyr Asn Gly Val Ile Glu Glu Phe Leu Ala Thr 
            260                 265                 270         


Gly Glu Lys Leu Phe Gly Pro Tyr Val Trp Gly Arg Tyr Asp Leu Leu 
        275                 280                 285             


Phe Met Pro Pro Ser Phe Pro Phe Gly Gly Met Glu Asn Pro Cys Leu 
    290                 295                 300                 


Thr Phe Val Thr Pro Cys Leu Leu Ala Gly Asp Arg Ser Leu Ala Asp 
305                 310                 315                 320 


Val Ile Ile His Glu Ile Ser His Ser Trp Phe Gly Asn Leu Val Thr 
                325                 330                 335     


Asn Ala Asn Trp Gly Glu Phe Trp Leu Asn Glu Gly Phe Thr Met Tyr 
            340                 345                 350         


Ala Gln Arg Arg Ile Ser Thr Ile Leu Phe Gly Ala Ala Tyr Thr Cys 
        355                 360                 365             


Leu Glu Ala Ala Thr Gly Arg Ala Leu Leu Arg Gln His Met Asp Ile 
    370                 375                 380                 


Thr Gly Glu Glu Asn Pro Leu Asn Lys Leu Arg Val Lys Ile Glu Pro 
385                 390                 395                 400 


Gly Val Asp Pro Asp Asp Thr Tyr Asn Glu Thr Pro Tyr Glu Lys Gly 
                405                 410                 415     


Phe Cys Phe Val Ser Tyr Leu Ala His Leu Val Gly Asp Gln Asp Gln 
            420                 425                 430         


Phe Asp Ser Phe Leu Lys Ala Tyr Val His Glu Phe Lys Phe Arg Ser 
        435                 440                 445             


Ile Leu Ala Asp Asp Phe Leu Asp Phe Tyr Leu Glu Tyr Phe Pro Glu 
    450                 455                 460                 


Leu Lys Lys Lys Arg Val Asp Ile Ile Pro Gly Phe Glu Phe Asp Arg 
465                 470                 475                 480 


Trp Leu Asn Thr Pro Gly Trp Pro Pro Tyr Leu Pro Asp Leu Ser Pro 
                485                 490                 495     


Gly Asp Ser Leu Met Lys Pro Ala Glu Glu Leu Ala Gln Leu Trp Ala 
            500                 505                 510         


Ala Glu Glu Leu Asp Met Lys Ala Ile Glu Ala Val Ala Ile Ser Pro 
        515                 520                 525             


Trp Lys Thr Tyr Gln Leu Val Tyr Phe Leu Asp Lys Ile Leu Gln Lys 
    530                 535                 540                 


Ser Pro Leu Pro Pro Gly Asn Val Lys Lys Leu Gly Asp Thr Tyr Pro 
545                 550                 555                 560 


Ser Ile Ser Asn Ala Arg Asn Ala Glu Leu Arg Leu Arg Trp Gly Gln 
                565                 570                 575     


Ile Val Leu Lys Asn Asp His Gln Glu Asp Phe Trp Lys Val Lys Glu 
            580                 585                 590         


Phe Leu His Asn Gln Gly Lys Gln Lys Tyr Thr Leu Pro Leu Tyr His 
        595                 600                 605             


Ala Met Met Gly Gly Ser Glu Val Ala Gln Thr Leu Ala Lys Glu Thr 
    610                 615                 620                 


Phe Ala Ser Thr Ala Ser Gln Leu His Ser Asn Val Val Asn Tyr Val 
625                 630                 635                 640 


Gln Gln Ile Val Ala Pro Lys Gly Ser 
                645                 


<210>  2926
<211>  427
<212>  PRT
<213>  Homo Sapiens

<400>  2926

Ala Glu Thr Thr Pro Gly Ala Pro Arg Ala Leu Ser Leu Gly Ser Pro 
1               5                   10                  15      


Ser Leu Phe Thr Thr Pro Gly Val Pro Ser Ala Leu Thr Thr Pro Gly 
            20                  25                  30          


Leu Thr Thr Pro Gly Thr Pro Lys Thr Leu Asp Leu Arg Gly Arg Ala 
        35                  40                  45              


Gln Ala Leu Met Arg Ser Phe Pro Leu Val Asp Gly His Asn Asp Leu 
    50                  55                  60                  


Pro Gln Val Leu Arg Gln Arg Tyr Lys Asn Val Leu Gln Asp Val Asn 
65                  70                  75                  80  


Leu Arg Asn Phe Ser His Gly Gln Thr Ser Leu Asp Arg Leu Arg Asp 
                85                  90                  95      


Gly Leu Val Gly Ala Gln Phe Trp Ser Ala Ser Val Ser Cys Gln Ser 
            100                 105                 110         


Gln Asp Gln Thr Ala Val Arg Leu Ala Leu Glu Gln Ile Asp Leu Ile 
        115                 120                 125             


His Arg Met Cys Ala Ser Tyr Ser Glu Leu Glu Leu Val Thr Ser Ala 
    130                 135                 140                 


Glu Gly Leu Asn Ser Ser Gln Lys Leu Ala Cys Leu Ile Gly Val Glu 
145                 150                 155                 160 


Gly Gly His Ser Leu Asp Ser Ser Leu Ser Val Leu Arg Ser Phe Tyr 
                165                 170                 175     


Val Leu Gly Val Arg Tyr Leu Thr Leu Thr Phe Thr Cys Ser Thr Pro 
            180                 185                 190         


Trp Ala Glu Ser Ser Thr Lys Phe Arg His His Met Tyr Thr Asn Val 
        195                 200                 205             


Ser Gly Leu Thr Ser Phe Gly Glu Lys Val Val Glu Glu Leu Asn Arg 
    210                 215                 220                 


Leu Gly Met Met Ile Asp Leu Ser Tyr Ala Ser Asp Thr Leu Ile Arg 
225                 230                 235                 240 


Arg Val Leu Glu Val Ser Gln Ala Pro Val Ile Phe Ser His Ser Ala 
                245                 250                 255     


Ala Arg Ala Val Cys Asp Asn Leu Leu Asn Val Pro Asp Asp Ile Leu 
            260                 265                 270         


Gln Leu Leu Lys Lys Asn Gly Gly Ile Val Met Val Thr Leu Ser Met 
        275                 280                 285             


Gly Val Leu Gln Cys Asn Leu Leu Ala Asn Val Ser Thr Val Ala Asp 
    290                 295                 300                 


His Phe Asp His Ile Arg Ala Val Ile Gly Ser Glu Phe Ile Gly Ile 
305                 310                 315                 320 


Gly Gly Asn Tyr Asp Gly Thr Gly Arg Phe Pro Gln Gly Leu Glu Asp 
                325                 330                 335     


Val Ser Thr Tyr Pro Val Leu Ile Glu Glu Leu Leu Ser Arg Ser Trp 
            340                 345                 350         


Ser Glu Glu Glu Leu Gln Gly Val Leu Arg Gly Asn Leu Leu Arg Val 
        355                 360                 365             


Phe Arg Gln Val Glu Lys Val Arg Glu Glu Ser Arg Ala Gln Ser Pro 
    370                 375                 380                 


Val Glu Ala Glu Phe Pro Tyr Gly Gln Leu Ser Thr Ser Cys His Ser 
385                 390                 395                 400 


His Leu Val Pro Gln Asn Gly His Gln Ala Thr His Leu Glu Val Thr 
                405                 410                 415     


Lys Gln Pro Thr Asn Arg Val Pro Trp Arg Ser 
            420                 425         


<210>  2927
<211>  811
<212>  PRT
<213>  Homo Sapiens

<400>  2927

Ser Gly Gly Gly Gly Asp Ser Arg Gln Arg Arg Leu Leu Ala Ala Lys 
1               5                   10                  15      


Val Asn Lys His Lys Pro Trp Ile Glu Thr Ser Tyr His Gly Val Ile 
            20                  25                  30          


Thr Glu Asn Asn Asp Thr Val Ile Leu Asp Pro Pro Leu Val Ala Leu 
        35                  40                  45              


Asp Lys Asp Ala Pro Val Pro Phe Ala Gly Glu Ile Cys Ala Phe Lys 
    50                  55                  60                  


Ile His Gly Gln Glu Leu Pro Phe Glu Ala Val Val Leu Asn Lys Thr 
65                  70                  75                  80  


Ser Gly Glu Gly Arg Leu Arg Ala Lys Ser Pro Ile Asp Cys Glu Leu 
                85                  90                  95      


Gln Lys Glu Tyr Thr Phe Ile Ile Gln Ala Tyr Asp Cys Gly Ala Gly 
            100                 105                 110         


Pro His Glu Thr Ala Trp Lys Lys Ser His Lys Ala Val Val His Ile 
        115                 120                 125             


Gln Val Lys Asp Val Asn Glu Phe Ala Pro Thr Phe Lys Glu Pro Ala 
    130                 135                 140                 


Tyr Lys Ala Val Val Thr Glu Gly Lys Ile Tyr Asp Ser Ile Leu Gln 
145                 150                 155                 160 


Val Glu Ala Ile Asp Glu Asp Cys Ser Pro Gln Tyr Ser Gln Ile Cys 
                165                 170                 175     


Asn Tyr Glu Ile Val Thr Thr Asp Val Pro Phe Ala Ile Asp Arg Asn 
            180                 185                 190         


Gly Asn Ile Arg Asn Thr Glu Lys Leu Ser Tyr Asp Lys Gln His Gln 
        195                 200                 205             


Tyr Glu Ile Leu Val Thr Ala Tyr Asp Cys Gly Gln Lys Pro Ala Ala 
    210                 215                 220                 


Gln Asp Thr Leu Val Gln Val Asp Val Lys Pro Val Cys Lys Pro Gly 
225                 230                 235                 240 


Trp Gln Asp Trp Thr Lys Arg Ile Glu Tyr Gln Pro Gly Ser Gly Ser 
                245                 250                 255     


Met Pro Leu Phe Pro Ser Ile His Leu Glu Thr Cys Asp Gly Ala Val 
            260                 265                 270         


Ser Ser Leu Gln Ile Val Thr Glu Leu Gln Thr Asn Tyr Ile Gly Lys 
        275                 280                 285             


Gly Cys Asp Arg Glu Thr Tyr Ser Glu Lys Ser Leu Gln Lys Leu Cys 
    290                 295                 300                 


Gly Ala Ser Ser Gly Ile Ile Asp Leu Leu Pro Ser Pro Ser Ala Ala 
305                 310                 315                 320 


Thr Asn Trp Thr Ala Gly Leu Leu Val Asp Ser Ser Glu Met Ile Phe 
                325                 330                 335     


Lys Phe Asp Gly Arg Gln Gly Ala Lys Val Pro Asp Gly Ile Val Pro 
            340                 345                 350         


Lys Asn Leu Thr Asp Gln Phe Thr Ile Thr Met Trp Met Lys His Gly 
        355                 360                 365             


Pro Ser Pro Gly Val Arg Ala Glu Lys Glu Thr Ile Leu Cys Asn Ser 
    370                 375                 380                 


Asp Lys Thr Glu Met Asn Arg His His Tyr Ala Leu Tyr Val His Asn 
385                 390                 395                 400 


Cys Arg Leu Val Phe Leu Leu Arg Lys Asp Phe Asp Gln Ala Asp Thr 
                405                 410                 415     


Phe Arg Pro Ala Glu Phe His Trp Lys Leu Asp Gln Ile Cys Asp Lys 
            420                 425                 430         


Glu Trp His Tyr Tyr Val Ile Asn Val Glu Phe Pro Val Val Thr Leu 
        435                 440                 445             


Tyr Met Asp Gly Ala Thr Tyr Glu Pro Tyr Leu Val Thr Asn Asp Trp 
    450                 455                 460                 


Pro Ile His Pro Ser His Ile Ala Met Gln Leu Thr Val Gly Ala Cys 
465                 470                 475                 480 


Trp Gln Gly Gly Glu Val Thr Lys Pro Gln Phe Ala Gln Phe Phe His 
                485                 490                 495     


Gly Ser Leu Ala Ser Leu Thr Ile Arg Pro Gly Lys Met Glu Ser Gln 
            500                 505                 510         


Lys Val Ile Ser Cys Leu Gln Ala Cys Lys Glu Gly Leu Asp Ile Asn 
        515                 520                 525             


Ser Leu Glu Ser Leu Gly Gln Gly Ile Lys Tyr His Phe Asn Pro Ser 
    530                 535                 540                 


Gln Ser Ile Leu Val Met Glu Gly Asp Asp Ile Gly Asn Ile Asn Arg 
545                 550                 555                 560 


Ala Leu Gln Lys Val Ser Tyr Ile Asn Ser Arg Gln Phe Pro Thr Ala 
                565                 570                 575     


Gly Val Arg Arg Leu Lys Val Ser Ser Lys Val Gln Cys Phe Gly Glu 
            580                 585                 590         


Asp Val Cys Ile Ser Ile Pro Glu Val Asp Ala Tyr Val Met Val Leu 
        595                 600                 605             


Gln Ala Ile Glu Pro Arg Ile Thr Leu Arg Gly Thr Asp His Phe Trp 
    610                 615                 620                 


Arg Pro Ala Ala Gln Phe Glu Ser Ala Arg Gly Val Thr Leu Phe Pro 
625                 630                 635                 640 


Asp Ile Lys Ile Val Ser Thr Phe Ala Lys Thr Glu Ala Pro Gly Asp 
                645                 650                 655     


Val Lys Thr Thr Asp Pro Lys Ser Glu Val Leu Glu Glu Met Leu His 
            660                 665                 670         


Asn Leu Asp Phe Cys Asp Ile Leu Val Ile Gly Gly Asp Leu Asp Pro 
        675                 680                 685             


Arg Gln Glu Cys Leu Glu Leu Asn His Ser Glu Leu His Gln Arg His 
    690                 695                 700                 


Leu Asp Ala Thr Asn Ser Thr Ala Gly Tyr Ser Ile Tyr Gly Val Gly 
705                 710                 715                 720 


Ser Met Ser Arg Tyr Glu Gln Val Leu His His Ile Arg Tyr Arg Asn 
                725                 730                 735     


Trp Arg Pro Ala Ser Leu Glu Ala Arg Arg Phe Arg Ile Lys Cys Ser 
            740                 745                 750         


Glu Leu Asn Gly Arg Tyr Thr Ser Asn Glu Phe Asn Leu Glu Val Ser 
        755                 760                 765             


Ile Leu His Glu Asp Gln Val Ser Asp Lys Glu His Val Asn His Leu 
    770                 775                 780                 


Ile Val Gln Pro Pro Phe Leu Gln Ser Val His His Pro Glu Ser Arg 
785                 790                 795                 800 


Ser Ser Ile Gln His Ser Ser Val Val Pro Ser 
                805                 810     


<210>  2928
<211>  409
<212>  PRT
<213>  Homo Sapiens

<400>  2928

His Arg Thr Thr Gly Pro Arg Phe Leu Ile Ser Asp Arg Asp Pro Gln 
1               5                   10                  15      


Cys Asn Leu His Cys Ser Arg Thr Gln Pro Lys Pro Ile Cys Ala Ser 
            20                  25                  30          


Asp Gly Arg Ser Tyr Glu Ser Met Cys Glu Tyr Gln Arg Ala Lys Cys 
        35                  40                  45              


Arg Asp Pro Thr Leu Gly Val Val His Arg Gly Arg Cys Lys Asp Ala 
    50                  55                  60                  


Gly Gln Ser Lys Cys Arg Leu Glu Arg Ala Gln Ala Leu Glu Gln Ala 
65                  70                  75                  80  


Lys Lys Pro Gln Glu Ala Val Phe Val Pro Glu Cys Gly Glu Asp Gly 
                85                  90                  95      


Ser Phe Thr Gln Val Gln Cys His Thr Tyr Thr Gly Tyr Cys Trp Cys 
            100                 105                 110         


Val Thr Pro Asp Gly Lys Pro Ile Ser Gly Ser Ser Val Gln Asn Lys 
        115                 120                 125             


Thr Pro Val Cys Ser Gly Ser Val Thr Asp Lys Pro Leu Ser Gln Gly 
    130                 135                 140                 


Asn Ser Gly Arg Lys Asp Asp Gly Ser Lys Pro Thr Pro Thr Met Glu 
145                 150                 155                 160 


Thr Gln Pro Val Phe Asp Gly Asp Glu Ile Thr Ala Pro Thr Leu Trp 
                165                 170                 175     


Ile Lys His Leu Val Ile Lys Asp Ser Lys Leu Asn Asn Thr Asn Ile 
            180                 185                 190         


Arg Asn Ser Glu Lys Val Tyr Ser Cys Asp Gln Glu Arg Gln Ser Ala 
        195                 200                 205             


Leu Glu Glu Ala Gln Gln Asn Pro Arg Glu Gly Ile Val Ile Pro Glu 
    210                 215                 220                 


Cys Ala Pro Gly Gly Leu Tyr Lys Pro Val Gln Cys His Gln Ser Thr 
225                 230                 235                 240 


Gly Tyr Cys Trp Cys Val Leu Val Asp Thr Gly Arg Pro Leu Pro Gly 
                245                 250                 255     


Thr Ser Thr Arg Tyr Val Met Pro Ser Cys Glu Ser Asp Ala Arg Ala 
            260                 265                 270         


Lys Thr Thr Glu Ala Asp Asp Pro Phe Lys Asp Arg Glu Leu Pro Gly 
        275                 280                 285             


Cys Pro Glu Gly Lys Lys Met Glu Phe Ile Thr Ser Leu Leu Asp Ala 
    290                 295                 300                 


Leu Thr Thr Asp Met Val Gln Ala Ile Asn Ser Ala Ala Pro Thr Gly 
305                 310                 315                 320 


Gly Gly Arg Phe Ser Glu Pro Asp Pro Ser His Thr Leu Glu Glu Arg 
                325                 330                 335     


Val Val His Trp Tyr Phe Ser Gln Leu Asp Ser Asn Ser Ser Asn Asp 
            340                 345                 350         


Ile Asn Lys Arg Glu Met Lys Pro Phe Lys Arg Tyr Val Lys Lys Lys 
        355                 360                 365             


Ala Lys Pro Lys Lys Cys Ala Arg Arg Phe Thr Asp Tyr Cys Asp Leu 
    370                 375                 380                 


Asn Lys Asp Lys Val Ile Ser Leu Pro Glu Leu Lys Gly Cys Leu Gly 
385                 390                 395                 400 


Val Ser Lys Glu Val Gly Arg Leu Val 
                405                 


<210>  2929
<211>  119
<212>  PRT
<213>  Homo Sapiens

<400>  2929

Trp His Phe His Glu Gln Arg Asp Cys Asp Glu His Asn Val Met Ala 
1               5                   10                  15      


Arg Tyr Leu Pro Ala Thr Val Glu Phe Ala Val His Thr Phe Asn Gln 
            20                  25                  30          


Gln Ser Lys Asp Tyr Tyr Ala Tyr Arg Leu Gly His Ile Leu Asn Ser 
        35                  40                  45              


Trp Lys Glu Gln Val Glu Ser Lys Thr Val Phe Ser Met Glu Leu Leu 
    50                  55                  60                  


Leu Gly Arg Thr Arg Cys Gly Lys Phe Glu Asp Asp Ile Asp Asn Cys 
65                  70                  75                  80  


His Phe Gln Glu Ser Thr Glu Leu Asn Asn Thr Phe Thr Cys Phe Phe 
                85                  90                  95      


Thr Ile Ser Thr Arg Pro Trp Met Thr Gln Phe Ser Leu Leu Asn Lys 
            100                 105                 110         


Thr Cys Leu Glu Gly Phe His 
        115                 


<210>  2930
<211>  638
<212>  PRT
<213>  Homo Sapiens

<400>  2930

Phe Glu Ile Ala Leu Pro Arg Glu Ser Asn Ile Thr Val Leu Ile Lys 
1               5                   10                  15      


Leu Gly Thr Pro Thr Leu Leu Ala Lys Pro Cys Tyr Ile Val Ile Ser 
            20                  25                  30          


Lys Arg His Ile Thr Met Leu Ser Ile Lys Ser Gly Glu Arg Ile Val 
        35                  40                  45              


Phe Thr Phe Ser Cys Gln Ser Pro Glu Asn His Phe Val Ile Glu Ile 
    50                  55                  60                  


Gln Lys Asn Ile Asp Cys Met Ser Gly Pro Cys Pro Phe Gly Glu Val 
65                  70                  75                  80  


Gln Leu Gln Pro Ser Thr Ser Leu Leu Pro Thr Leu Asn Arg Thr Phe 
                85                  90                  95      


Ile Trp Asp Val Lys Ala His Lys Ser Ile Gly Leu Glu Leu Gln Phe 
            100                 105                 110         


Ser Ile Pro Arg Leu Arg Gln Ile Gly Pro Gly Glu Ser Cys Pro Asp 
        115                 120                 125             


Gly Val Thr His Ser Ile Ser Gly Arg Ile Asp Ala Thr Val Val Arg 
    130                 135                 140                 


Ile Gly Thr Phe Cys Ser Asn Gly Thr Val Ser Arg Ile Lys Met Gln 
145                 150                 155                 160 


Glu Gly Val Lys Met Ala Leu His Leu Pro Trp Phe His Pro Arg Asn 
                165                 170                 175     


Val Ser Gly Phe Ser Ile Ala Asn Arg Ser Ser Ile Lys Arg Leu Cys 
            180                 185                 190         


Ile Ile Glu Ser Val Phe Glu Gly Glu Gly Ser Ala Thr Leu Met Ser 
        195                 200                 205             


Ala Asn Tyr Pro Glu Gly Phe Pro Glu Asp Glu Leu Met Thr Trp Gln 
    210                 215                 220                 


Phe Val Val Pro Ala His Leu Arg Ala Ser Val Ser Phe Leu Asn Phe 
225                 230                 235                 240 


Asn Leu Ser Asn Cys Glu Arg Lys Glu Glu Arg Val Glu Tyr Tyr Ile 
                245                 250                 255     


Pro Gly Ser Thr Thr Asn Pro Glu Val Phe Lys Leu Glu Asp Lys Gln 
            260                 265                 270         


Pro Gly Asn Met Ala Gly Asn Phe Asn Leu Ser Leu Gln Gly Cys Asp 
        275                 280                 285             


Gln Asp Ala Gln Ser Pro Gly Ile Leu Arg Leu Gln Phe Gln Val Leu 
    290                 295                 300                 


Val Gln His Pro Gln Asn Glu Ser Asn Lys Ile Tyr Val Val Asp Leu 
305                 310                 315                 320 


Ser Asn Glu Arg Ala Met Ser Leu Thr Ile Glu Pro Arg Pro Val Lys 
                325                 330                 335     


Gln Ser Arg Lys Phe Val Pro Gly Cys Phe Val Cys Leu Glu Ser Arg 
            340                 345                 350         


Thr Cys Ser Ser Asn Leu Thr Leu Thr Ser Gly Ser Lys His Lys Ile 
        355                 360                 365             


Ser Phe Leu Cys Asp Asp Leu Thr Arg Leu Trp Met Asn Val Glu Lys 
    370                 375                 380                 


Thr Ile Ser Cys Thr Asp His Arg Tyr Cys Gln Arg Lys Ser Tyr Ser 
385                 390                 395                 400 


Leu Gln Val Pro Ser Asp Ile Leu His Leu Pro Val Glu Leu His Asp 
                405                 410                 415     


Phe Ser Trp Lys Leu Leu Val Pro Lys Asp Arg Leu Ser Leu Val Leu 
            420                 425                 430         


Val Pro Ala Gln Lys Leu Gln Gln His Thr His Glu Lys Pro Cys Asn 
        435                 440                 445             


Thr Ser Phe Ser Tyr Leu Val Ala Ser Ala Ile Pro Ser Gln Asp Leu 
    450                 455                 460                 


Tyr Phe Gly Ser Phe Cys Pro Gly Gly Ser Ile Lys Gln Ile Gln Val 
465                 470                 475                 480 


Lys Gln Asn Ile Ser Val Thr Leu Arg Thr Phe Ala Pro Ser Phe Gln 
                485                 490                 495     


Gln Glu Ala Ser Arg Gln Gly Leu Thr Val Ser Phe Ile Pro Tyr Phe 
            500                 505                 510         


Lys Glu Glu Gly Val Phe Thr Val Thr Pro Asp Thr Lys Ser Lys Val 
        515                 520                 525             


Tyr Leu Arg Thr Pro Asn Trp Asp Arg Gly Leu Pro Ser Leu Thr Ser 
    530                 535                 540                 


Val Ser Trp Asn Ile Ser Val Pro Arg Asp Gln Val Ala Cys Leu Thr 
545                 550                 555                 560 


Phe Phe Lys Glu Arg Ser Gly Val Val Cys Gln Thr Gly Arg Ala Phe 
                565                 570                 575     


Met Ile Ile Gln Glu Gln Arg Thr Arg Ala Glu Glu Ile Phe Ser Leu 
            580                 585                 590         


Asp Glu Asp Val Leu Pro Lys Pro Ser Phe His His His Ser Phe Trp 
        595                 600                 605             


Val Asn Ile Ser Asn Cys Ser Pro Thr Ser Gly Lys Gln Leu Asp Leu 
    610                 615                 620                 


Leu Phe Ser Val Thr Leu Thr Pro Arg Thr Val Asp Leu Thr 
625                 630                 635             


<210>  2931
<211>  318
<212>  PRT
<213>  Homo Sapiens

<400>  2931

Ala Leu Thr His Val Leu Cys Arg Pro Arg Arg Gly Cys Cys Gly Arg 
1               5                   10                  15      


Arg Arg Ser Ala Ser Pro Ala Cys Leu Ser Asp Pro Ser Leu Gly Glu 
            20                  25                  30          


His Gly Phe Leu Asn Leu Lys Ser Ser Gly Leu Arg Leu His Tyr Val 
        35                  40                  45              


Ser Ala Gly Arg Gly Asn Gly Pro Leu Met Leu Phe Leu His Gly Phe 
    50                  55                  60                  


Pro Glu Asn Trp Phe Ser Trp Arg Tyr Gln Leu Arg Glu Phe Gln Ser 
65                  70                  75                  80  


Arg Phe His Val Val Ala Val Asp Leu Arg Gly Tyr Gly Pro Ser Asp 
                85                  90                  95      


Ala Pro Arg Asp Val Asp Cys Tyr Thr Ile Asp Leu Leu Leu Val Asp 
            100                 105                 110         


Ile Lys Asp Val Ile Leu Gly Leu Gly Tyr Ser Lys Cys Ile Leu Val 
        115                 120                 125             


Ala His Asp Trp Gly Ala Leu Leu Ala Trp His Phe Ser Ile Tyr Tyr 
    130                 135                 140                 


Pro Ser Leu Val Glu Arg Met Val Val Val Ser Gly Ala Pro Met Ser 
145                 150                 155                 160 


Val Tyr Gln Asp Tyr Ser Leu His His Ile Ser Gln Phe Phe Arg Ser 
                165                 170                 175     


His Tyr Met Phe Leu Phe Gln Leu Pro Trp Leu Pro Glu Lys Leu Leu 
            180                 185                 190         


Ser Met Ser Asp Phe Gln Ile Leu Lys Thr Thr Leu Thr His Arg Lys 
        195                 200                 205             


Thr Gly Ile Pro Cys Leu Thr Pro Ser Glu Leu Glu Ala Phe Leu Tyr 
    210                 215                 220                 


Asn Phe Ser Gln Pro Gly Gly Leu Thr Gly Pro Leu Asn Tyr Tyr Arg 
225                 230                 235                 240 


Asn Leu Phe Arg Asn Phe Pro Leu Glu Pro Gln Glu Leu Thr Thr Pro 
                245                 250                 255     


Thr Leu Leu Leu Trp Gly Glu Lys Asp Thr Tyr Leu Glu Leu Gly Leu 
            260                 265                 270         


Val Glu Ala Ile Gly Ser Arg Phe Val Pro Gly Arg Leu Glu Ala His 
        275                 280                 285             


Ile Leu Pro Gly Ile Gly His Trp Ile Pro Gln Ser Asn Pro Gln Glu 
    290                 295                 300                 


Met His Gln Tyr Met Trp Ala Phe Leu Gln Asp Leu Leu Asp 
305                 310                 315             


<210>  2932
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  2932

Thr Leu Arg Thr Ser Leu Asp Pro Ser Leu Glu Ile Tyr Lys Lys Met 
1               5                   10                  15      


Phe Glu Val Lys Arg Arg Glu Gln Leu Leu Ala Leu Lys Asn Leu Ala 
            20                  25                  30          


Gln Leu Asn Asp Ile His Gln Gln Tyr Lys Ile Leu Asp Val Met Leu 
        35                  40                  45              


Lys Gly Leu Phe Lys Val Leu Glu Asp Ser Arg Thr Val Leu Thr Ala 
    50                  55                  60                  


Ala Asp Val Leu Pro Asp Gly Pro Phe Pro Gln Asp Glu Lys Leu Lys 
65                  70                  75                  80  


Asp Ala Phe Ser His Val Val Glu Asn Thr Ala Phe Phe Gly Asp Val 
                85                  90                  95      


Val Leu Arg Phe Pro Arg Ile Val His Tyr Tyr Phe Asp His Asn Ser 
            100                 105                 110         


Asn Trp Asn Leu Leu Ile Arg Trp Gly Ile Ser Phe Cys Asn Gln Thr 
        115                 120                 125             


Gly Val Phe Asn Gln Gly Pro His Ser Pro Ile Leu Ser Leu Met Ala 
    130                 135                 140                 


Gln Glu Leu Gly Ile Ser Glu Lys Asp Ser Asn Phe Gln Asn Pro Phe 
145                 150                 155                 160 


Lys Ile Asp Arg Thr Glu Phe Ile Pro Ser Thr Asp Pro Phe Gln Lys 
                165                 170                 175     


Ala Leu Arg Glu Glu Glu Lys Arg Arg Lys Lys Glu Glu Lys Arg Lys 
            180                 185                 190         


Glu Ile Arg Lys Gly Pro Arg Ile Ser Arg Ser Gln Ser Glu Leu 
        195                 200                 205         


<210>  2933
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  2933

Thr Phe Lys Gln Glu Glu Arg Ala Val Arg Asp Arg Asn Leu Leu Gln 
1               5                   10                  15      


Val His Asp His Asn Gln Pro Ile Pro Trp Lys Val Gln Phe Asn Leu 
            20                  25                  30          


Gly Asn Ser Ser Arg Pro Ser Asn Gln Cys Arg Asn Ser Ile Gln Gly 
        35                  40                  45              


Lys His Leu Ile Thr Asp Glu Leu Gly Tyr Val Cys Glu Arg Lys Asp 
    50                  55                  60                  


Leu Leu Val Asn Gly Cys Cys Asn Val Asn Val Pro Ser Thr Lys Gln 
65                  70                  75                  80  


Tyr Cys Cys Asp Gly Cys Trp Pro Asn Gly Cys Cys Ser Ala Tyr Glu 
                85                  90                  95      


Tyr Cys Val Ser Cys Cys Leu Gln Pro Asn Lys Gln Leu Leu Leu Glu 
            100                 105                 110         


Arg Phe Leu Asn Arg Ala Ala Val Ala Phe Gln Asn Leu Phe Met Ala 
        115                 120                 125             


Val Glu Asp His Phe Glu Leu Cys Leu Ala Lys Cys Arg Thr Ser Ser 
    130                 135                 140                 


Gln Ser Val Gln His Glu Asn Thr Tyr Arg Asp Pro Ile Ala Lys Tyr 
145                 150                 155                 160 


Cys Tyr Gly Glu Ser Pro Pro Glu Leu Phe Pro Ala 
                165                 170         


<210>  2934
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  2934

Arg Lys Asn Arg Pro Ala Gly Ala Ile His Ser Pro Tyr Lys Asp Gly 
1               5                   10                  15      


Ser Ser Asn Asn Ser Glu Arg Trp Gln His Gln Ile Lys Glu Val Leu 
            20                  25                  30          


Ala Ser Ser Gln Glu Ala Leu Val Val Thr Glu Arg Lys Tyr Leu Lys 
        35                  40                  45              


Ser Asp Trp Cys Lys Thr Gln Pro Leu Arg Gln Thr Val Ser Glu Glu 
    50                  55                  60                  


Gly Cys Arg Ser Arg Thr Ile Leu Asn Arg Phe Cys Tyr Gly Gln Cys 
65                  70                  75                  80  


Asn Ser Phe Tyr Ile Pro Arg His Val Lys Lys Glu Glu Glu Ser Phe 
                85                  90                  95      


Gln Ser Cys Ala Phe Cys Lys Pro Gln Arg Val Thr Ser Val Leu Val 
            100                 105                 110         


Glu Leu Glu Cys Pro Gly Leu Asp Pro Pro Phe Arg Leu Lys Lys Ile 
        115                 120                 125             


Gln Lys Val Lys Gln Cys Arg Cys Met Ser Val Asn Leu Ser Asp Ser 
    130                 135                 140                 


Asp Lys Gln 
145         


<210>  2935
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  2935

Leu Ser Pro Pro Thr Met Asn Leu Arg Pro Pro Lys Ser Cys Gly Asn 
1               5                   10                  15      


Val Phe Tyr Trp Val Leu Val Leu Asn Ser Gly Leu Leu Tyr Lys Phe 
            20                  25                  30          


Cys Gln Thr Ile Lys Cys Arg Ala Asn Trp Arg Pro Ala Arg Ala Pro 
        35                  40                  45              


Arg Gly Trp Asn Glu Ala Thr Glu Arg His Gln Glu Arg Arg Thr Gln 
    50                  55                  60                  


Met Glu Thr Glu Met Gly Gly Ile Ser Thr Thr Tyr Trp His Arg Leu 
65                  70                  75                  80  


Cys Thr Cys Thr Asp Arg Arg Ala Glu Lys Leu Val Met Asp Gly Asn 
                85                  90                  95      


Asn Cys Trp Phe His Lys 
            100         


<210>  2936
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  2936

Trp Ile Cys Lys Lys Trp Phe Pro Tyr Phe Leu Val Arg Phe Thr Val 
1               5                   10                  15      


Ile Tyr Asn Glu Gln Met Ala Ser Lys Lys Arg Glu Leu Phe Ser Asn 
            20                  25                  30          


Leu Gln Glu Phe Ala Gly Pro Ser Gly Lys Leu Ser Leu Leu Glu Val 
        35                  40                  45              


Gly Cys Gly Thr Gly Ala Asn Phe Lys Phe Tyr Pro Pro Gly Cys Arg 
    50                  55                  60                  


Val Thr Cys Ile Asp Pro Asn Pro Asn Phe Glu Lys Phe Leu Ile Lys 
65                  70                  75                  80  


Ser Ile Ala Glu Asn Arg His Leu Gln Phe Glu Arg Phe Val Val Ala 
                85                  90                  95      


Ala Gly Glu Asn Met His Gln Val Ala Asp Gly Ser Val Asp Val Val 
            100                 105                 110         


Val Cys Thr Leu Val Leu Cys Ser Val Lys Asn Gln Glu Arg Ile Leu 
        115                 120                 125             


Arg Glu Val Cys Arg Val Leu Arg Pro Gly Gly Ala Phe Tyr Phe Met 
    130                 135                 140                 


Glu His Val Ala Ala Glu Cys Ser Thr Trp Asn Tyr Phe Trp Gln Gln 
145                 150                 155                 160 


Val Leu Asp Pro Ala Trp His Leu Leu Phe Asp Gly Cys Asn Leu Thr 
                165                 170                 175     


Arg Glu Ser Trp Lys Ala Leu Glu Arg Ala Ser Phe Ser Lys Leu Lys 
            180                 185                 190         


Leu Gln His Ile Gln Ala Pro Leu Ser Trp Glu Leu Val Arg Pro His 
        195                 200                 205             


Ile Tyr Gly Tyr Ala Val Lys 
    210                 215 


<210>  2937
<211>  405
<212>  PRT
<213>  Homo Sapiens

<400>  2937

Gln Asn Cys Leu Lys Lys Ser Leu Glu Asp Val Val Ile Asp Ile Gln 
1               5                   10                  15      


Ser Ser Leu Ser Lys Gly Ile Arg Gly Asn Glu Pro Ile Tyr Thr Ser 
            20                  25                  30          


Thr Gln Glu Asp Cys Ile Asn Ser Cys Cys Ser Thr Lys Asn Ile Ser 
        35                  40                  45              


Gly Asp Lys Ala Cys Asn Leu Met Ile Phe Asp Thr Arg Lys Thr Ala 
    50                  55                  60                  


Arg Gln Pro Asn Cys Tyr Leu Phe Phe Cys Pro Asn Glu Glu Ala Cys 
65                  70                  75                  80  


Pro Leu Lys Pro Ala Lys Gly Leu Met Ser Tyr Arg Ile Ile Thr Asp 
                85                  90                  95      


Phe Pro Ser Leu Thr Arg Asn Leu Pro Ser Gln Glu Leu Pro Gln Glu 
            100                 105                 110         


Asp Ser Leu Leu His Gly Gln Phe Ser Gln Ala Val Thr Pro Leu Ala 
        115                 120                 125             


His His His Thr Asp Tyr Ser Lys Pro Thr Asp Ile Ser Trp Arg Asp 
    130                 135                 140                 


Thr Leu Ser Gln Lys Phe Gly Ser Ser Asp His Leu Glu Lys Leu Phe 
145                 150                 155                 160 


Lys Met Asp Glu Ala Ser Ala Gln Leu Leu Ala Tyr Lys Glu Lys Gly 
                165                 170                 175     


His Ser Gln Ser Ser Gln Phe Ser Ser Asp Gln Glu Ile Ala His Leu 
            180                 185                 190         


Leu Pro Glu Asn Val Ser Ala Leu Pro Ala Thr Val Ala Val Ala Ser 
        195                 200                 205             


Pro His Thr Thr Ser Ala Thr Pro Lys Pro Ala Thr Leu Leu Pro Thr 
    210                 215                 220                 


Asn Ala Ser Val Thr Pro Ser Gly Thr Ser Gln Pro Gln Leu Ala Thr 
225                 230                 235                 240 


Thr Ala Pro Pro Val Thr Thr Val Thr Ser Gln Pro Pro Thr Thr Leu 
                245                 250                 255     


Ile Ser Thr Val Phe Thr Arg Ala Ala Ala Thr Leu Gln Ala Met Ala 
            260                 265                 270         


Thr Thr Ala Val Leu Thr Thr Thr Phe Gln Ala Pro Thr Asp Ser Lys 
        275                 280                 285             


Gly Ser Leu Glu Thr Ile Pro Phe Thr Glu Ile Ser Asn Leu Thr Leu 
    290                 295                 300                 


Asn Thr Gly Asn Val Tyr Asn Pro Thr Ala Leu Ser Met Ser Asn Val 
305                 310                 315                 320 


Glu Ser Ser Thr Met Asn Lys Thr Ala Ser Trp Glu Gly Arg Glu Ala 
                325                 330                 335     


Ser Pro Gly Ser Ser Ser Gln Gly Ser Val Pro Glu Asn Gln Tyr Gly 
            340                 345                 350         


Leu Pro Phe Glu Lys Trp Leu Leu Ile Gly Ser Leu Leu Phe Gly Val 
        355                 360                 365             


Leu Phe Leu Val Ile Gly Leu Val Leu Leu Gly Arg Ile Leu Ser Glu 
    370                 375                 380                 


Ser Leu Arg Arg Lys Arg Tyr Ser Arg Leu Asp Tyr Leu Ile Asn Gly 
385                 390                 395                 400 


Ile Tyr Val Asp Ile 
                405 


<210>  2938
<211>  406
<212>  PRT
<213>  Homo Sapiens

<400>  2938

Leu Leu Ala Pro Val Phe Arg Thr Leu Ser Ile Leu Thr Asn Gln Ser 
1               5                   10                  15      


Asn Cys Trp Leu Cys Glu His Leu Asp Asn Ala Glu Gln Pro Glu Leu 
            20                  25                  30          


Val Phe Val Pro Ala Ser Ala Ser Thr Trp Trp Thr Tyr Ser Gly Gln 
        35                  40                  45              


Trp Met Tyr Glu Arg Val Trp Tyr Pro Gln Ala Glu Val Gln Asn His 
    50                  55                  60                  


Ser Thr Ser Ser Tyr Arg Lys Val Thr Trp His Trp Glu Ala Ser Met 
65                  70                  75                  80  


Glu Ala Gln Gly Leu Ser Phe Ala Gln Val Arg Leu Leu Glu Gly Asn 
                85                  90                  95      


Phe Ser Leu Cys Val Glu Asn Lys Asn Gly Ser Gly Pro Phe Leu Gly 
            100                 105                 110         


Asn Ile Pro Lys Gln Tyr Cys Asn Gln Ile Leu Trp Phe Asp Ser Thr 
        115                 120                 125             


Asp Gly Thr Phe Met Pro Ser Ile Asp Val Thr Asn Glu Ser Arg Asn 
    130                 135                 140                 


Asp Asp Asp Asp Thr Ser Val Cys Leu Gly Thr Arg Gln Cys Ser Trp 
145                 150                 155                 160 


Phe Ala Gly Cys Thr Asn Arg Thr Trp Asn Ser Ser Ala Val Pro Leu 
                165                 170                 175     


Ile Gly Leu Pro Asn Thr Gln Asp Tyr Lys Trp Val Asp Arg Asn Ser 
            180                 185                 190         


Gly Leu Thr Trp Ser Gly Asn Asp Thr Cys Leu Tyr Ser Cys Gln Asn 
        195                 200                 205             


Gln Thr Lys Gly Leu Leu Tyr Gln Leu Phe Arg Asn Leu Phe Cys Ser 
    210                 215                 220                 


Tyr Gly Leu Thr Glu Ala His Gly Lys Trp Arg Cys Ala Asp Ala Ser 
225                 230                 235                 240 


Ile Thr Asn Asp Lys Gly His Asp Gly His Arg Thr Pro Thr Trp Trp 
                245                 250                 255     


Leu Thr Gly Ser Asn Leu Thr Leu Ser Val Asn Asn Ser Gly Leu Phe 
            260                 265                 270         


Phe Leu Cys Gly Asn Gly Val Tyr Lys Gly Phe Pro Pro Lys Trp Ser 
        275                 280                 285             


Gly Arg Cys Gly Leu Gly Tyr Leu Val Pro Ser Leu Thr Arg Tyr Leu 
    290                 295                 300                 


Thr Leu Asn Ala Ser Gln Ile Thr Asn Leu Arg Ser Phe Ile His Lys 
305                 310                 315                 320 


Val Thr Pro His Arg Cys Thr Gln Gly Asp Thr Asp Asn Pro Pro Leu 
                325                 330                 335     


Tyr Cys Asn Pro Lys Asp Asn Ser Thr Ile Arg Ala Leu Phe Pro Ser 
            340                 345                 350         


Leu Gly Thr Tyr Asp Leu Glu Lys Ala Ile Leu Asn Ile Ser Lys Ala 
        355                 360                 365             


Met Glu Gln Glu Phe Ser Ala Thr Lys Gln Thr Leu Glu Ala His Gln 
    370                 375                 380                 


Ser Lys Val Ser Ser Leu Ala Ser Ala Ser Arg Lys Asp His Val Leu 
385                 390                 395                 400 


Asp Ile Pro Thr Thr Gln 
                405     


<210>  2939
<211>  500
<212>  PRT
<213>  Homo Sapiens

<400>  2939

Ile Gly Phe Arg Phe Ala Ser Tyr Ile Asn Asn Asp Met Val Leu Gln 
1               5                   10                  15      


Lys Glu Pro Ala Gly Ala Val Ile Trp Gly Phe Gly Thr Pro Gly Ala 
            20                  25                  30          


Thr Val Thr Val Thr Leu Arg Gln Gly Gln Glu Thr Ile Met Lys Lys 
        35                  40                  45              


Val Thr Ser Val Lys Ala His Ser Asp Thr Trp Met Val Val Leu Asp 
    50                  55                  60                  


Pro Met Lys Pro Gly Gly Pro Phe Glu Val Met Ala Gln Gln Thr Leu 
65                  70                  75                  80  


Glu Lys Ile Asn Phe Thr Leu Arg Val His Asp Val Leu Phe Gly Asp 
                85                  90                  95      


Val Trp Leu Cys Ser Gly Gln Ser Asn Met Gln Met Thr Val Leu Gln 
            100                 105                 110         


Ile Phe Asn Ala Thr Arg Glu Leu Ser Asn Thr Ala Ala Tyr Gln Ser 
        115                 120                 125             


Val Arg Ile Leu Ser Val Ser Pro Ile Gln Ala Glu Gln Glu Leu Glu 
    130                 135                 140                 


Asp Leu Val Ala Val Asp Leu Gln Trp Ser Lys Pro Thr Ser Glu Asn 
145                 150                 155                 160 


Leu Gly His Gly Tyr Phe Lys Tyr Met Ser Ala Val Cys Trp Leu Phe 
                165                 170                 175     


Gly Arg His Leu Tyr Asp Thr Leu Gln Tyr Pro Ile Gly Leu Ile Ala 
            180                 185                 190         


Ser Ser Trp Gly Gly Thr Pro Ile Glu Ala Trp Ser Ser Gly Arg Ser 
        195                 200                 205             


Leu Lys Ala Cys Gly Val Pro Lys Gln Gly Ser Ile Pro Tyr Asp Ser 
    210                 215                 220                 


Val Thr Gly Pro Ser Lys His Ser Val Leu Trp Asn Ala Met Ile His 
225                 230                 235                 240 


Pro Leu Cys Asn Met Thr Leu Lys Gly Val Val Trp Tyr Gln Gly Glu 
                245                 250                 255     


Ser Asn Ile Asn Tyr Asn Thr Asp Leu Tyr Asn Cys Thr Phe Pro Ala 
            260                 265                 270         


Leu Ile Glu Asp Trp Arg Glu Thr Phe His Arg Gly Ser Gln Gly Gln 
        275                 280                 285             


Thr Glu Arg Phe Phe Pro Phe Gly Leu Val Gln Leu Ser Ser Asp Leu 
    290                 295                 300                 


Ser Lys Lys Ser Ser Asp Asp Gly Phe Pro Gln Ile Arg Trp His Gln 
305                 310                 315                 320 


Thr Ala Asp Phe Gly Tyr Val Pro Asn Pro Lys Met Pro Asn Thr Phe 
                325                 330                 335     


Met Ala Val Ala Met Asp Leu Cys Asp Arg Asp Ser Pro Phe Gly Ser 
            340                 345                 350         


Ile His Pro Arg Asp Lys Gln Thr Val Ala Tyr Arg Leu His Leu Gly 
        355                 360                 365             


Ala Arg Ala Leu Ala Tyr Gly Glu Lys Asn Leu Thr Phe Glu Gly Pro 
    370                 375                 380                 


Leu Pro Glu Lys Ile Glu Leu Leu Ala His Lys Gly Leu Leu Asn Leu 
385                 390                 395                 400 


Thr Tyr Tyr Gln Gln Ile Gln Val Gln Lys Lys Asp Asn Lys Ile Phe 
                405                 410                 415     


Glu Ile Ser Cys Cys Ser Asp His Arg Cys Lys Trp Leu Pro Ala Ser 
            420                 425                 430         


Met Asn Thr Val Ser Thr Gln Ser Leu Thr Leu Ala Ile Asp Ser Cys 
        435                 440                 445             


His Gly Thr Val Val Ala Leu Arg Tyr Ala Trp Thr Thr Trp Pro Cys 
    450                 455                 460                 


Glu Tyr Lys Gln Cys Pro Leu Tyr His Pro Ser Ser Ala Leu Pro Ala 
465                 470                 475                 480 


Pro Pro Phe Ile Ala Phe Ile Thr Asp Gln Gly Pro Gly His Gln Ser 
                485                 490                 495     


Asn Val Ala Lys 
            500 


<210>  2940
<211>  462
<212>  PRT
<213>  Homo Sapiens

<400>  2940

Gly Lys Leu Leu Val Val Pro Met Asp Gly Ser His Trp Phe Thr Met 
1               5                   10                  15      


Gln Ser Val Val Glu Lys Leu Ile Leu Arg Gly His Glu Val Val Val 
            20                  25                  30          


Val Met Pro Glu Val Ser Trp Gln Leu Gly Arg Ser Leu Asn Cys Thr 
        35                  40                  45              


Val Lys Thr Tyr Ser Thr Ser Tyr Thr Leu Glu Asp Gln Asp Arg Glu 
    50                  55                  60                  


Phe Met Val Phe Ala Asp Ala Arg Trp Thr Ala Pro Leu Arg Ser Ala 
65                  70                  75                  80  


Phe Ser Leu Leu Thr Ser Ser Ser Asn Gly Ile Phe Asp Leu Phe Phe 
                85                  90                  95      


Ser Asn Cys Arg Ser Leu Phe Asn Asp Arg Lys Leu Val Glu Tyr Leu 
            100                 105                 110         


Lys Glu Ser Cys Phe Asp Ala Val Phe Leu Asp Pro Phe Asp Ala Cys 
        115                 120                 125             


Gly Leu Ile Val Ala Lys Tyr Phe Ser Leu Pro Ser Val Val Phe Ala 
    130                 135                 140                 


Arg Gly Ile Phe Cys His Tyr Leu Glu Glu Gly Ala Gln Cys Pro Ala 
145                 150                 155                 160 


Pro Leu Ser Tyr Val Pro Arg Leu Leu Leu Gly Phe Ser Asp Ala Met 
                165                 170                 175     


Thr Phe Lys Glu Arg Val Trp Asn His Ile Met His Leu Glu Glu His 
            180                 185                 190         


Leu Phe Cys Pro Tyr Phe Phe Lys Asn Val Leu Glu Ile Ala Ser Glu 
        195                 200                 205             


Ile Leu Gln Thr Pro Val Thr Ala Tyr Asp Leu Tyr Ser His Thr Ser 
    210                 215                 220                 


Ile Trp Leu Leu Arg Thr Asp Phe Val Leu Glu Tyr Pro Lys Pro Val 
225                 230                 235                 240 


Met Pro Asn Met Ile Phe Ile Gly Gly Ile Asn Cys His Gln Gly Lys 
                245                 250                 255     


Pro Val Pro Met Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu His 
            260                 265                 270         


Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro Glu 
        275                 280                 285             


Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile Pro Gln Thr 
    290                 295                 300                 


Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn Asn 
305                 310                 315                 320 


Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His Pro 
                325                 330                 335     


Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr Glu 
            340                 345                 350         


Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly Asp 
        355                 360                 365             


Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val Thr 
    370                 375                 380                 


Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu Lys 
385                 390                 395                 400 


Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu Ser 
                405                 410                 415     


Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val Phe 
            420                 425                 430         


Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg Pro 
        435                 440                 445             


Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460         


<210>  2941
<211>  462
<212>  PRT
<213>  Homo Sapiens

<400>  2941

Gly Lys Leu Leu Val Val Pro Met Asp Gly Ser His Trp Phe Thr Met 
1               5                   10                  15      


Gln Ser Val Val Glu Lys Leu Ile Leu Arg Gly His Glu Val Val Val 
            20                  25                  30          


Val Met Pro Glu Val Ser Trp Gln Leu Gly Lys Ser Leu Asn Cys Thr 
        35                  40                  45              


Val Lys Thr Tyr Ser Thr Ser Tyr Thr Leu Glu Asp Leu Asp Arg Glu 
    50                  55                  60                  


Phe Met Asp Phe Ala Asp Ala Gln Trp Lys Ala Gln Val Arg Ser Leu 
65                  70                  75                  80  


Phe Ser Leu Phe Leu Ser Ser Ser Asn Gly Phe Phe Asn Leu Phe Phe 
                85                  90                  95      


Ser His Cys Arg Ser Leu Phe Asn Asp Arg Lys Leu Val Glu Tyr Leu 
            100                 105                 110         


Lys Glu Ser Ser Phe Asp Ala Val Phe Leu Asp Pro Phe Asp Ala Cys 
        115                 120                 125             


Gly Leu Ile Val Ala Lys Tyr Phe Ser Leu Pro Ser Val Val Phe Ala 
    130                 135                 140                 


Arg Gly Ile Ala Cys His Tyr Leu Glu Glu Gly Ala Gln Cys Pro Ala 
145                 150                 155                 160 


Pro Leu Ser Tyr Val Pro Arg Ile Leu Leu Gly Phe Ser Asp Ala Met 
                165                 170                 175     


Thr Phe Lys Glu Arg Val Arg Asn His Ile Met His Leu Glu Glu His 
            180                 185                 190         


Leu Phe Cys Gln Tyr Phe Ser Lys Asn Ala Leu Glu Ile Ala Ser Glu 
        195                 200                 205             


Ile Leu Gln Thr Pro Val Thr Ala Tyr Asp Leu Tyr Ser His Thr Ser 
    210                 215                 220                 


Ile Trp Leu Leu Arg Thr Asp Phe Val Leu Asp Tyr Pro Lys Pro Val 
225                 230                 235                 240 


Met Pro Asn Met Ile Phe Ile Gly Gly Ile Asn Cys His Gln Gly Lys 
                245                 250                 255     


Pro Leu Pro Met Glu Phe Glu Ala Tyr Ile Asn Ala Ser Gly Glu His 
            260                 265                 270         


Gly Ile Val Val Phe Ser Leu Gly Ser Met Val Ser Glu Ile Pro Glu 
        275                 280                 285             


Lys Lys Ala Met Ala Ile Ala Asp Ala Leu Gly Lys Ile Pro Gln Thr 
    290                 295                 300                 


Val Leu Trp Arg Tyr Thr Gly Thr Arg Pro Ser Asn Leu Ala Asn Asn 
305                 310                 315                 320 


Thr Ile Leu Val Lys Trp Leu Pro Gln Asn Asp Leu Leu Gly His Pro 
                325                 330                 335     


Met Thr Arg Ala Phe Ile Thr His Ala Gly Ser His Gly Val Tyr Glu 
            340                 345                 350         


Ser Ile Cys Asn Gly Val Pro Met Val Met Met Pro Leu Phe Gly Asp 
        355                 360                 365             


Gln Met Asp Asn Ala Lys Arg Met Glu Thr Lys Gly Ala Gly Val Thr 
    370                 375                 380                 


Leu Asn Val Leu Glu Met Thr Ser Glu Asp Leu Glu Asn Ala Leu Lys 
385                 390                 395                 400 


Ala Val Ile Asn Asp Lys Ser Tyr Lys Glu Asn Ile Met Arg Leu Ser 
                405                 410                 415     


Ser Leu His Lys Asp Arg Pro Val Glu Pro Leu Asp Leu Ala Val Phe 
            420                 425                 430         


Trp Val Glu Phe Val Met Arg His Lys Gly Ala Pro His Leu Arg Pro 
        435                 440                 445             


Ala Ala His Asp Leu Thr Trp Tyr Gln Tyr His Ser Leu Asp 
    450                 455                 460         


<210>  2942
<211>  426
<212>  PRT
<213>  Homo Sapiens

<400>  2942

Ala Val Ile Asp Trp Pro Thr Glu Glu Gly Lys Glu Val Trp Asp Tyr 
1               5                   10                  15      


Val Thr Val Arg Lys Asp Ala Tyr Met Phe Trp Trp Leu Tyr Tyr Ala 
            20                  25                  30          


Thr Asn Ser Cys Lys Asn Phe Ser Glu Leu Pro Leu Val Met Trp Leu 
        35                  40                  45              


Gln Gly Gly Pro Gly Gly Ser Ser Thr Gly Phe Gly Asn Phe Glu Glu 
    50                  55                  60                  


Ile Gly Pro Leu Asp Ser Asp Leu Lys Pro Arg Lys Thr Thr Trp Leu 
65                  70                  75                  80  


Gln Ala Ala Ser Leu Leu Phe Val Asp Asn Pro Val Gly Thr Gly Phe 
                85                  90                  95      


Ser Tyr Val Asn Gly Ser Gly Ala Tyr Ala Lys Asp Leu Ala Met Val 
            100                 105                 110         


Ala Ser Asp Met Met Val Leu Leu Lys Thr Phe Phe Ser Cys His Lys 
        115                 120                 125             


Glu Phe Gln Thr Val Pro Phe Tyr Ile Phe Ser Glu Ser Tyr Gly Gly 
    130                 135                 140                 


Lys Met Ala Ala Gly Ile Gly Leu Glu Leu Tyr Lys Ala Ile Gln Arg 
145                 150                 155                 160 


Gly Thr Ile Lys Cys Asn Phe Ala Gly Val Ala Leu Gly Asp Ser Trp 
                165                 170                 175     


Ile Ser Pro Val Asp Ser Val Leu Ser Trp Gly Pro Tyr Leu Tyr Ser 
            180                 185                 190         


Met Ser Leu Leu Glu Asp Lys Gly Leu Ala Glu Val Ser Lys Val Ala 
        195                 200                 205             


Glu Gln Val Leu Asn Ala Val Asn Lys Gly Leu Tyr Arg Glu Ala Thr 
    210                 215                 220                 


Glu Leu Trp Gly Lys Ala Glu Met Ile Ile Glu Gln Asn Thr Asp Gly 
225                 230                 235                 240 


Val Asn Phe Tyr Asn Ile Leu Thr Lys Ser Thr Pro Thr Ser Thr Met 
                245                 250                 255     


Glu Ser Ser Leu Glu Phe Thr Gln Ser His Leu Val Cys Leu Cys Gln 
            260                 265                 270         


Arg His Val Arg His Leu Gln Arg Asp Ala Leu Ser Gln Leu Met Asn 
        275                 280                 285             


Gly Pro Ile Arg Lys Lys Leu Lys Ile Ile Pro Glu Asp Gln Ser Trp 
    290                 295                 300                 


Gly Gly Gln Ala Thr Asn Val Phe Val Asn Met Glu Glu Asp Phe Met 
305                 310                 315                 320 


Lys Pro Val Ile Ser Ile Val Asp Glu Leu Leu Glu Ala Gly Ile Asn 
                325                 330                 335     


Val Thr Val Tyr Asn Gly Gln Leu Asp Leu Ile Val Asp Thr Met Gly 
            340                 345                 350         


Gln Glu Ala Trp Val Arg Lys Leu Lys Trp Pro Glu Leu Pro Lys Phe 
        355                 360                 365             


Ser Gln Leu Lys Trp Lys Ala Leu Tyr Ser Asp Pro Lys Ser Leu Glu 
    370                 375                 380                 


Thr Ser Ala Phe Val Lys Ser Tyr Lys Asn Leu Ala Phe Tyr Trp Ile 
385                 390                 395                 400 


Leu Lys Ala Gly His Met Val Pro Ser Asp Gln Gly Asp Met Ala Leu 
                405                 410                 415     


Lys Met Met Arg Leu Val Thr Gln Gln Glu 
            420                 425     


<210>  2943
<211>  190
<212>  PRT
<213>  Homo Sapiens

<400>  2943

Gln Ser Pro Met Thr Val Leu Cys Ser Ile Asp Trp Phe Met Val Thr 
1               5                   10                  15      


Val His Pro Phe Met Leu Asn Asn Asp Val Cys Val His Phe His Glu 
            20                  25                  30          


Leu His Leu Gly Leu Gly Cys Pro Pro Asn His Val Gln Pro His Ala 
        35                  40                  45              


Tyr Gln Phe Thr Tyr Arg Val Thr Glu Cys Gly Ile Arg Ala Lys Ala 
    50                  55                  60                  


Val Ser Gln Asp Met Val Ile Tyr Ser Thr Glu Ile His Tyr Ser Ser 
65                  70                  75                  80  


Lys Gly Thr Pro Ser Lys Phe Val Ile Pro Val Ser Cys Ala Ala Pro 
                85                  90                  95      


Gln Lys Ser Pro Trp Leu Thr Lys Pro Cys Ser Met Arg Val Ala Ser 
            100                 105                 110         


Lys Ser Arg Ala Thr Ala Gln Lys Asp Glu Lys Cys Tyr Glu Val Phe 
        115                 120                 125             


Ser Leu Ser Gln Ser Ser Gln Arg Pro Asn Cys Asp Cys Pro Pro Cys 
    130                 135                 140                 


Val Phe Ser Glu Glu Glu His Thr Gln Val Pro Cys His Gln Ala Gly 
145                 150                 155                 160 


Ala Gln Glu Ala Gln Pro Leu Gln Pro Ser His Phe Leu Asp Ile Ser 
                165                 170                 175     


Glu Asp Trp Ser Leu His Thr Asp Asp Met Ile Gly Ser Met 
            180                 185                 190 


<210>  2944
<211>  52
<212>  PRT
<213>  Homo Sapiens

<400>  2944

Met Gly Phe Ile Phe Ser Lys Ser Met Asn Glu Ser Met Lys Asn Gln 
1               5                   10                  15      


Lys Glu Phe Met Leu Met Asn Ala Arg Leu Gln Leu Glu Arg Gln Leu 
            20                  25                  30          


Ile Met Gln Ser Glu Met Arg Glu Arg Gln Met Ala Met Gln Ile Ala 
        35                  40                  45              


Trp Ser Arg Glu 
    50          


<210>  2945
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  2945

Thr Asn Val Thr Ala Ala Val Gln Asp Ala Gly Leu Ala His Glu Gly 
1               5                   10                  15      


Glu Gly Glu Glu Glu Thr Glu Asn Asn Asp Ser Glu Thr Ala Glu Asn 
            20                  25                  30          


Tyr Ala Pro Pro Glu Thr Glu Asp Val Ser Asn Arg Asn Val Val Lys 
        35                  40                  45              


Glu Val Glu Phe Gly Met Cys Thr Val Thr Cys Gly Ile Gly Val Arg 
    50                  55                  60                  


Glu Val Ile Leu Thr Asn Gly Cys Pro Gly Gly Glu Ser Lys Cys Val 
65                  70                  75                  80  


Val Arg Val Glu Glu Cys Arg Gly Pro Thr Asp Cys Gly Trp Gly Lys 
                85                  90                  95      


Pro Ile Ser Glu Ser Leu Glu Ser Val Arg Leu Ala Cys Ile His Thr 
            100                 105                 110         


Ser Pro Leu Asn Arg Phe Lys Tyr Met Trp Lys Leu Leu Arg Gln Asp 
        115                 120                 125             


Gln Gln Ser Ile Ile Leu Val Asn Asp Ser Ala Ile Leu Glu Val Arg 
    130                 135                 140                 


Lys Glu Ser His Pro Leu Ala Phe Glu Cys Asp Thr Leu Asp Asn Asn 
145                 150                 155                 160 


Glu Ile Val Ala Thr Ile Lys Phe Thr Val Tyr Thr Ser Ser Glu Leu 
                165                 170                 175     


Gln Met Arg Arg Ser Ser Leu Pro Ala Thr Asp Ala Ala Leu Ile Phe 
            180                 185                 190         


<210>  2946
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  2946

Ala Val Ile Thr Gly Ala Cys Asp Lys Asp Ser Gln Cys Gly Gly Gly 
1               5                   10                  15      


Met Cys Cys Ala Val Ser Ile Trp Val Lys Ser Ile Arg Ile Cys Thr 
            20                  25                  30          


Pro Met Gly Lys Leu Gly Asp Ser Cys His Pro Leu Thr Arg Lys Asn 
        35                  40                  45              


Asn Phe Gly Asn Gly Arg Gln Glu Arg Arg Lys Arg Lys Arg Ser Lys 
    50                  55                  60                  


Arg Lys Lys Glu Val Pro Phe Phe Gly Arg Arg Met His His Thr Cys 
65                  70                  75                  80  


Pro Cys Leu Pro Gly Leu Ala Cys Leu Arg Thr Ser Phe Asn Arg Phe 
                85                  90                  95      


Ile Cys Leu Ala Gln Lys 
            100         


<210>  2947
<211>  189
<212>  PRT
<213>  Homo Sapiens

<400>  2947

Lys Asn Ile Trp Lys Arg Ala Leu Pro Ala Arg Leu Ala Glu Lys Ser 
1               5                   10                  15      


Arg Ala Glu Glu Ala Gly Ala Pro Gly Gly Pro Arg Gln Pro Arg Ala 
            20                  25                  30          


Asp Arg Cys Pro Pro Pro Pro Arg Thr Leu Pro Pro Gly Ala Cys Gln 
        35                  40                  45              


Ala Ala Arg Cys Gln Ala Asp Ser Glu Cys Pro Arg His Arg Arg Cys 
    50                  55                  60                  


Cys Tyr Asn Gly Cys Ala Tyr Ala Cys Leu Glu Ala Val Pro Pro Pro 
65                  70                  75                  80  


Pro Val Leu Asp Trp Leu Val Gln Pro Lys Pro Arg Trp Leu Gly Gly 
                85                  90                  95      


Asn Gly Trp Leu Leu Asp Gly Pro Glu Glu Val Leu Gln Ala Glu Ala 
            100                 105                 110         


Cys Ser Thr Thr Glu Asp Gly Ala Glu Pro Leu Leu Cys Pro Ser Gly 
        115                 120                 125             


Tyr Glu Cys His Ile Leu Ser Pro Gly Asp Val Ala Glu Gly Ile Pro 
    130                 135                 140                 


Asn Arg Gly Gln Cys Val Lys Gln Arg Arg Gln Ala Asp Gly Arg Ile 
145                 150                 155                 160 


Leu Arg His Lys Leu Tyr Lys Glu Tyr Pro Glu Gly Asp Ser Lys Asn 
                165                 170                 175     


Val Ala Glu Pro Gly Arg Gly Gln Gln Lys His Phe Gln 
            180                 185                 


<210>  2948
<211>  63
<212>  PRT
<213>  Homo Sapiens

<400>  2948

Glu Gln Lys Glu Leu Asp Leu Met Asp Leu Val Gly Glu Asp Arg Lys 
1               5                   10                  15      


Trp Met Met Ala Arg Lys Leu Met Gln Val Asn Asp Thr Leu Thr Ser 
            20                  25                  30          


Glu Asp Ala Gly Leu Arg Asn Ser Lys Asn Cys Thr Glu Pro Ala Leu 
        35                  40                  45              


His Glu Phe Pro Asn Asp Ile Phe Thr Asn Glu Asp Arg Arg Gln 
    50                  55                  60              


<210>  2949
<211>  779
<212>  PRT
<213>  Homo Sapiens

<400>  2949

Phe Ser Asp Glu Thr Leu Asp Lys Val Pro Lys Ser Glu Gly Tyr Cys 
1               5                   10                  15      


Ser Arg Ile Leu Arg Ala Gln Gly Thr Arg Arg Glu Gly Tyr Thr Glu 
            20                  25                  30          


Phe Ser Leu Arg Val Glu Gly Asp Pro Asp Phe Tyr Lys Pro Gly Thr 
        35                  40                  45              


Ser Tyr Arg Val Thr Leu Ser Ala Ala Pro Pro Ser Tyr Phe Arg Gly 
    50                  55                  60                  


Phe Thr Leu Ile Ala Leu Arg Glu Asn Arg Glu Gly Asp Lys Glu Glu 
65                  70                  75                  80  


Asp His Ala Gly Thr Phe Gln Ile Ile Asp Glu Glu Glu Thr Gln Phe 
                85                  90                  95      


Met Ser Asn Cys Pro Val Ala Val Thr Glu Ser Thr Pro Arg Arg Arg 
            100                 105                 110         


Thr Arg Ile Gln Val Phe Trp Ile Ala Pro Pro Ala Gly Thr Gly Cys 
        115                 120                 125             


Val Ile Leu Lys Ala Ser Ile Val Gln Lys Arg Ile Ile Tyr Phe Gln 
    130                 135                 140                 


Asp Glu Gly Ser Leu Thr Lys Lys Leu Cys Glu Gln Asp Ser Thr Phe 
145                 150                 155                 160 


Asp Gly Val Thr Asp Lys Pro Ile Leu Asp Cys Cys Ala Cys Gly Thr 
                165                 170                 175     


Ala Lys Tyr Arg Leu Thr Phe Tyr Gly Asn Trp Ser Glu Lys Thr His 
            180                 185                 190         


Pro Lys Asp Tyr Pro Arg Arg Ala Asn His Trp Ser Ala Ile Ile Gly 
        195                 200                 205             


Gly Ser His Ser Lys Asn Tyr Val Leu Trp Glu Tyr Gly Gly Tyr Ala 
    210                 215                 220                 


Ser Glu Gly Val Lys Gln Val Ala Glu Leu Gly Ser Pro Val Lys Met 
225                 230                 235                 240 


Glu Glu Glu Ile Arg Gln Gln Ser Asp Glu Val Leu Thr Val Ile Lys 
                245                 250                 255     


Ala Lys Ala Gln Trp Pro Ala Trp Gln Pro Leu Asn Val Arg Ala Ala 
            260                 265                 270         


Pro Ser Ala Glu Phe Ser Val Asp Arg Thr Arg His Leu Met Ser Phe 
        275                 280                 285             


Leu Thr Met Met Gly Pro Ser Pro Asp Trp Asn Val Gly Leu Ser Ala 
    290                 295                 300                 


Glu Asp Leu Cys Thr Lys Glu Cys Gly Trp Val Gln Lys Val Val Gln 
305                 310                 315                 320 


Asp Leu Ile Pro Trp Asp Ala Gly Thr Asp Ser Gly Val Thr Tyr Glu 
                325                 330                 335     


Ser Pro Asn Lys Pro Thr Ile Pro Gln Glu Lys Ile Arg Pro Leu Thr 
            340                 345                 350         


Ser Leu Asp His Pro Gln Ser Pro Phe Tyr Asp Pro Glu Gly Gly Ser 
        355                 360                 365             


Ile Thr Gln Val Ala Arg Val Val Ile Glu Arg Ile Ala Arg Lys Gly 
    370                 375                 380                 


Glu Gln Cys Asn Ile Val Pro Asp Asn Val Asp Asp Ile Val Ala Asp 
385                 390                 395                 400 


Leu Ala Pro Glu Glu Lys Asp Glu Asp Asp Thr Pro Glu Thr Cys Ile 
                405                 410                 415     


Tyr Ser Asn Trp Ser Pro Trp Ser Ala Cys Ser Ser Ser Thr Cys Asp 
            420                 425                 430         


Lys Gly Lys Arg Met Arg Gln Arg Met Leu Lys Ala Gln Leu Asp Leu 
        435                 440                 445             


Ser Val Pro Cys Pro Asp Thr Gln Asp Phe Gln Pro Cys Met Gly Pro 
    450                 455                 460                 


Gly Cys Ser Asp Glu Asp Gly Ser Thr Cys Thr Met Ser Glu Trp Ile 
465                 470                 475                 480 


Thr Trp Ser Pro Cys Ser Ile Ser Cys Gly Met Gly Met Arg Ser Arg 
                485                 490                 495     


Glu Arg Tyr Val Lys Gln Phe Pro Glu Asp Gly Ser Val Cys Thr Leu 
            500                 505                 510         


Pro Thr Glu Glu Thr Glu Lys Cys Thr Val Asn Glu Glu Cys Ser Pro 
        515                 520                 525             


Ser Ser Cys Leu Met Thr Glu Trp Gly Glu Trp Asp Glu Cys Ser Ala 
    530                 535                 540                 


Thr Cys Gly Met Gly Met Lys Lys Arg His Arg Met Ile Lys Met Asn 
545                 550                 555                 560 


Pro Ala Asp Gly Ser Met Cys Lys Ala Glu Thr Ser Gln Ala Glu Lys 
                565                 570                 575     


Cys Met Met Pro Glu Cys His Thr Ile Pro Cys Leu Leu Ser Pro Trp 
            580                 585                 590         


Ser Glu Trp Ser Asp Cys Ser Val Thr Cys Gly Lys Gly Met Arg Thr 
        595                 600                 605             


Arg Gln Arg Met Leu Lys Ser Leu Ala Glu Leu Gly Asp Cys Asn Glu 
    610                 615                 620                 


Asp Leu Glu Gln Val Glu Lys Cys Met Leu Pro Glu Cys Pro Ile Asp 
625                 630                 635                 640 


Cys Glu Leu Thr Glu Trp Ser Gln Trp Ser Glu Cys Asn Lys Ser Cys 
                645                 650                 655     


Gly Lys Gly His Val Ile Arg Thr Arg Met Ile Gln Met Glu Pro Gln 
            660                 665                 670         


Phe Gly Gly Ala Pro Cys Pro Glu Thr Val Gln Arg Lys Lys Cys Arg 
        675                 680                 685             


Ile Arg Lys Cys Leu Arg Asn Pro Ser Ile Gln Lys Leu Arg Trp Arg 
    690                 695                 700                 


Glu Ala Arg Glu Ser Arg Arg Ser Glu Gln Leu Lys Glu Glu Ser Glu 
705                 710                 715                 720 


Gly Glu Gln Phe Pro Gly Cys Arg Met Arg Pro Trp Thr Ala Trp Ser 
                725                 730                 735     


Glu Cys Thr Lys Leu Cys Gly Gly Gly Ile Gln Glu Arg Tyr Met Thr 
            740                 745                 750         


Val Lys Lys Arg Phe Lys Ser Ser Gln Phe Thr Ser Cys Lys Asp Lys 
        755                 760                 765             


Lys Glu Ile Arg Ala Cys Asn Val His Pro Cys 
    770                 775                 


<210>  2950
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  2950

Ser Ser Pro Cys Ile Met Glu Pro Arg Asp Leu Pro Pro Lys Pro Gly 
1               5                   10                  15      


Leu Val Gly His Arg Gly Ala Pro Met Leu Ala Pro Glu Asn Thr Leu 
            20                  25                  30          


Met Ser Leu Arg Lys Thr Ala Glu Cys Gly Ala Thr Val Phe Glu Thr 
        35                  40                  45              


Asp Val Met Val Ser Ser Asp Gly Val Pro Phe Leu Met His Asp Glu 
    50                  55                  60                  


His Leu Ser Arg Thr Thr Asn Val Ala Ser Val Phe Pro Thr Arg Ile 
65                  70                  75                  80  


Thr Ala His Ser Ser Asp Phe Ser Trp Thr Glu Leu Lys Arg Leu Asn 
                85                  90                  95      


Ala Gly Ser Trp Phe Leu Glu Arg Arg Pro Phe Trp Gly Ala Lys Pro 
            100                 105                 110         


Leu Ala Gly Pro Asp Gln Lys Glu Ala Glu Ser Gln Thr Val Pro Ala 
        115                 120                 125             


Leu Glu Glu Leu Leu Glu Glu Ala Ala Ala Leu Asn Leu Ser Ile Met 
    130                 135                 140                 


Phe Asp Leu Arg Arg Pro Pro Gln Asn His Thr Tyr Tyr Asp Thr Phe 
145                 150                 155                 160 


Val Ile Gln Thr Leu Glu Thr Val Leu Asn Ala Arg Val Pro Gln Ala 
                165                 170                 175     


Met Val Phe Trp Leu Pro Asp Glu Asp Arg Ala Asn Val Gln Arg Arg 
            180                 185                 190         


Ala Pro Gly Met Arg Gln Ile Tyr Gly Arg Gln Gly Gly Asn Arg Thr 
        195                 200                 205             


Glu Arg Pro Gln Phe Leu Asn Leu Pro Tyr Gln Asp Leu Pro Leu Leu 
    210                 215                 220                 


Asp Ile Lys Ala Leu His Lys Asp Asn Val Ser Val Asn Leu Phe Val 
225                 230                 235                 240 


Val Asn Lys Pro Trp Leu Phe Ser Leu Leu Trp Cys Ala Gly Val Asp 
                245                 250                 255     


Ser Val Thr Thr Asn Asp Cys Gln Leu Leu Gln Gln Met Arg Tyr Pro 
            260                 265                 270         


Ile Trp Leu Ile Thr Pro Gln Thr Tyr 
        275                 280     


<210>  2951
<211>  193
<212>  PRT
<213>  Homo Sapiens

<400>  2951

Ala Lys Thr Gly Ala Glu Leu Val Thr Cys Gly Ser Val Leu Lys Leu 
1               5                   10                  15      


Leu Asn Thr His His Arg Val Arg Leu His Ser His Asp Ile Lys Tyr 
            20                  25                  30          


Gly Ser Gly Ser Gly Gln Gln Ser Val Thr Gly Val Glu Ala Ser Asp 
        35                  40                  45              


Asp Ala Asn Ser Tyr Trp Arg Ile Arg Gly Gly Ser Glu Gly Gly Cys 
    50                  55                  60                  


Pro Arg Gly Ser Pro Val Arg Cys Gly Gln Ala Val Arg Leu Thr His 
65                  70                  75                  80  


Val Leu Thr Gly Lys Asn Leu His Thr His His Phe Pro Ser Pro Leu 
                85                  90                  95      


Ser Asn Asn Gln Glu Val Ser Ala Phe Gly Glu Asp Gly Glu Gly Asp 
            100                 105                 110         


Asp Leu Asp Leu Trp Thr Val Arg Cys Ser Gly Gln His Trp Glu Arg 
        115                 120                 125             


Glu Ala Ala Val Arg Phe Gln His Val Gly Thr Ser Val Phe Leu Ser 
    130                 135                 140                 


Val Thr Gly Glu Gln Tyr Gly Ser Pro Ile Arg Gly Gln His Glu Val 
145                 150                 155                 160 


His Gly Met Pro Ser Ala Asn Thr His Asn Thr Trp Lys Ala Met Glu 
                165                 170                 175     


Gly Ile Phe Ile Lys Pro Ser Val Glu Pro Ser Ala Gly His Asp Glu 
            180                 185                 190         


Leu 
    


<210>  2952
<211>  51
<212>  PRT
<213>  Homo Sapiens

<400>  2952

Thr Ala Arg Phe Met Ala Phe Leu Lys Ala Thr Glu Ala Gln Leu Tyr 
1               5                   10                  15      


Val Asp Gln His Val Gln Asp Asp Thr Leu His Asn Val Ser Leu Pro 
            20                  25                  30          


Pro Glu Val Ala Tyr Phe Thr Tyr Ala Arg Asp Lys Trp Trp Pro Ser 
        35                  40                  45              


Asp Pro Gln 
    50      


<210>  2953
<211>  90
<212>  PRT
<213>  Homo Sapiens

<400>  2953

Lys Thr Leu Cys Ser Met Glu Glu Ala Ile Asn Glu Arg Ile Gln Glu 
1               5                   10                  15      


Val Ala Gly Ser Leu Ile Phe Arg Ala Ile Ser Ser Ile Gly Leu Glu 
            20                  25                  30          


Cys Gln Ser Val Thr Ser Arg Gly Asp Leu Ala Thr Cys Pro Arg Gly 
        35                  40                  45              


Phe Ala Val Thr Gly Cys Thr Cys Gly Ser Ala Cys Gly Ser Trp Asp 
    50                  55                  60                  


Val Arg Ala Glu Thr Thr Cys His Cys Gln Cys Ala Gly Met Asp Trp 
65                  70                  75                  80  


Thr Gly Ala Arg Cys Cys Arg Val Gln Pro 
                85                  90  


<210>  2954
<211>  355
<212>  PRT
<213>  Homo Sapiens

<400>  2954

Glu Ser Pro Ile Asp Pro Gln Pro Leu Ser Phe Lys Glu Pro Pro Leu 
1               5                   10                  15      


Leu Leu Gly Val Leu His Pro Asn Thr Lys Leu Arg Gln Ala Glu Arg 
            20                  25                  30          


Leu Phe Glu Asn Gln Leu Val Gly Pro Glu Ser Ile Ala His Ile Gly 
        35                  40                  45              


Asp Val Met Phe Thr Gly Thr Ala Asp Gly Arg Val Val Lys Leu Glu 
    50                  55                  60                  


Asn Gly Glu Ile Glu Thr Ile Ala Arg Phe Gly Ser Gly Pro Cys Lys 
65                  70                  75                  80  


Thr Arg Asp Asp Glu Pro Val Cys Gly Arg Pro Leu Gly Ile Arg Ala 
                85                  90                  95      


Gly Pro Asn Gly Thr Leu Phe Val Ala Asp Ala Tyr Lys Gly Leu Phe 
            100                 105                 110         


Glu Val Asn Pro Trp Lys Arg Glu Val Lys Leu Leu Leu Ser Ser Glu 
        115                 120                 125             


Thr Pro Ile Glu Gly Lys Asn Met Ser Phe Val Asn Asp Leu Thr Val 
    130                 135                 140                 


Thr Gln Asp Gly Arg Lys Ile Tyr Phe Thr Asp Ser Ser Ser Lys Trp 
145                 150                 155                 160 


Gln Arg Arg Asp Tyr Leu Leu Leu Val Met Glu Gly Thr Asp Asp Gly 
                165                 170                 175     


Arg Leu Leu Glu Tyr Asp Thr Val Thr Arg Glu Val Lys Val Leu Leu 
            180                 185                 190         


Asp Gln Leu Arg Phe Pro Asn Gly Val Gln Leu Ser Pro Ala Glu Asp 
        195                 200                 205             


Phe Val Leu Val Ala Glu Thr Thr Met Ala Arg Ile Arg Arg Val Tyr 
    210                 215                 220                 


Val Ser Gly Leu Met Lys Gly Gly Ala Asp Leu Phe Val Glu Asn Met 
225                 230                 235                 240 


Pro Gly Phe Pro Asp Asn Ile Arg Pro Ser Ser Ser Gly Gly Tyr Trp 
                245                 250                 255     


Val Gly Met Ser Thr Ile Arg Pro Asn Pro Gly Phe Ser Met Leu Asp 
            260                 265                 270         


Phe Leu Ser Glu Arg Pro Trp Ile Lys Arg Met Ile Phe Lys Leu Phe 
        275                 280                 285             


Ser Gln Glu Thr Val Met Lys Phe Val Pro Arg Tyr Ser Leu Val Leu 
    290                 295                 300                 


Glu Leu Ser Asp Ser Gly Ala Phe Arg Arg Ser Leu His Asp Pro Asp 
305                 310                 315                 320 


Gly Leu Val Ala Thr Tyr Ile Ser Glu Val His Glu His Asp Gly His 
                325                 330                 335     


Leu Tyr Leu Gly Ser Phe Arg Ser Pro Phe Leu Cys Arg Leu Ser Leu 
            340                 345                 350         


Gln Ala Val 
        355 


<210>  2955
<211>  390
<212>  PRT
<213>  Homo Sapiens

<400>  2955

Met Asn Gly Thr Arg Asn Trp Cys Thr Leu Val Asp Val His Pro Glu 
1               5                   10                  15      


Asp Gln Ala Ala Gly Ser Val Asp Ile Leu Arg Leu Thr Leu Gln Gly 
            20                  25                  30          


Glu Leu Thr Gly Asp Glu Leu Glu His Ile Ala Gln Lys Ala Gly Arg 
        35                  40                  45              


Lys Thr Tyr Ala Met Val Ser Ser His Ser Ala Gly His Ser Leu Ala 
    50                  55                  60                  


Ser Glu Leu Val Glu Ser His Asp Gly His Glu Glu Ile Ile Lys Val 
65                  70                  75                  80  


Tyr Leu Lys Gly Arg Ser Gly Asp Lys Met Ile His Glu Lys Asn Ile 
                85                  90                  95      


Asn Gln Leu Lys Ser Glu Val Gln Tyr Ile Gln Glu Ala Arg Asn Cys 
            100                 105                 110         


Leu Gln Lys Leu Arg Glu Asp Ile Ser Ser Lys Leu Asp Arg Asn Leu 
        115                 120                 125             


Gly Asp Ser Leu His Arg Gln Glu Ile Gln Val Val Leu Glu Lys Pro 
    130                 135                 140                 


Asn Gly Phe Ser Gln Ser Pro Thr Ala Leu Tyr Ser Ser Pro Pro Glu 
145                 150                 155                 160 


Val Asp Thr Cys Ile Asn Glu Asp Val Glu Ser Leu Arg Lys Thr Val 
                165                 170                 175     


Gln Asp Leu Leu Ala Lys Leu Gln Glu Ala Lys Arg Gln His Gln Ser 
            180                 185                 190         


Asp Cys Val Ala Phe Glu Val Thr Leu Ser Arg Tyr Gln Arg Glu Ala 
        195                 200                 205             


Glu Gln Ser Asn Val Ala Leu Gln Arg Glu Glu Asp Arg Val Glu Gln 
    210                 215                 220                 


Lys Glu Ala Glu Val Gly Glu Leu Gln Arg Arg Leu Leu Gly Met Glu 
225                 230                 235                 240 


Thr Glu His Gln Ala Leu Leu Ala Lys Val Arg Glu Gly Glu Val Ala 
                245                 250                 255     


Leu Glu Glu Leu Arg Ser Asn Asn Ala Asp Cys Gln Ala Glu Arg Glu 
            260                 265                 270         


Lys Ala Ala Thr Leu Glu Lys Glu Val Ala Gly Leu Arg Glu Lys Ile 
        275                 280                 285             


His His Leu Asp Asp Met Leu Lys Ser Gln Gln Arg Lys Val Arg Gln 
    290                 295                 300                 


Met Ile Glu Gln Leu Gln Asn Ser Lys Ala Val Ile Gln Ser Lys Asp 
305                 310                 315                 320 


Ala Thr Ile Gln Glu Leu Lys Glu Lys Ile Ala Tyr Leu Glu Ala Glu 
                325                 330                 335     


Asn Leu Glu Met His Asp Arg Met Glu His Leu Ile Glu Lys Gln Ile 
            340                 345                 350         


Ser His Gly Asn Phe Ser Thr Gln Ala Arg Ala Lys Thr Glu Asn Pro 
        355                 360                 365             


Gly Ser Ile Arg Ile Ser Lys Pro Pro Ser Pro Lys Pro Met Pro Val 
    370                 375                 380                 


Ile Arg Val Val Glu Thr 
385                 390 


<210>  2956
<211>  237
<212>  PRT
<213>  Homo Sapiens

<400>  2956

Gln Phe Gly Gly Leu Pro Val Pro Leu Asp Gln Thr Leu Pro Leu Asn 
1               5                   10                  15      


Val Asn Pro Ala Leu Pro Leu Ser Pro Thr Gly Leu Ala Gly Ser Leu 
            20                  25                  30          


Thr Asn Ala Leu Ser Asn Gly Leu Leu Ser Gly Gly Leu Leu Gly Ile 
        35                  40                  45              


Leu Glu Asn Leu Pro Leu Leu Asp Ile Leu Lys Pro Gly Gly Gly Thr 
    50                  55                  60                  


Ser Gly Gly Leu Leu Gly Gly Leu Leu Gly Lys Val Thr Ser Val Ile 
65                  70                  75                  80  


Pro Gly Leu Asn Asn Ile Ile Asp Ile Lys Val Thr Asp Pro Gln Leu 
                85                  90                  95      


Leu Glu Leu Gly Leu Val Gln Ser Pro Asp Gly His Arg Leu Tyr Val 
            100                 105                 110         


Thr Ile Pro Leu Gly Ile Lys Leu Gln Val Asn Thr Pro Leu Val Gly 
        115                 120                 125             


Ala Ser Leu Leu Arg Leu Ala Val Lys Leu Asp Ile Thr Ala Glu Ile 
    130                 135                 140                 


Leu Ala Val Arg Asp Lys Gln Glu Arg Ile His Leu Val Leu Gly Asp 
145                 150                 155                 160 


Cys Thr His Ser Pro Gly Ser Leu Gln Ile Ser Leu Leu Asp Gly Leu 
                165                 170                 175     


Gly Pro Leu Pro Ile Gln Gly Leu Leu Asp Ser Leu Thr Gly Ile Leu 
            180                 185                 190         


Asn Lys Val Leu Pro Glu Leu Val Gln Gly Asn Val Cys Pro Leu Val 
        195                 200                 205             


Asn Glu Val Leu Arg Gly Leu Asp Ile Thr Leu Val His Asp Ile Val 
    210                 215                 220                 


Asn Met Leu Ile His Gly Leu Gln Phe Val Ile Lys Val 
225                 230                 235         


<210>  2957
<211>  421
<212>  PRT
<213>  Homo Sapiens

<400>  2957

Val Pro Phe Phe Pro Gln Gln Ser Gly Thr Pro Gly Met Ala Ser Leu 
1               5                   10                  15      


Ser Leu Glu Thr Met Arg Gln Leu Gly Ser Leu Gln Arg Leu Asn Thr 
            20                  25                  30          


Leu Ser Gln Tyr Ser Arg Tyr Gly Phe Gly Lys Ser Phe Asn Ser Leu 
        35                  40                  45              


Trp Met His Gly Leu Leu Pro Pro His Ser Ser Leu Pro Trp Met Arg 
    50                  55                  60                  


Pro Arg Glu His Glu Thr Gln Gln Tyr Glu Tyr Ser Leu Pro Val His 
65                  70                  75                  80  


Pro Pro Pro Leu Pro Ser Gln Pro Ser Leu Lys Pro Gln Gln Pro Gly 
                85                  90                  95      


Leu Lys Pro Phe Leu Gln Ser Ala Ala Ala Thr Thr Asn Gln Ala Thr 
            100                 105                 110         


Ala Leu Lys Glu Ala Leu Gln Pro Pro Ile His Leu Gly His Leu Pro 
        115                 120                 125             


Leu Gln Glu Gly Glu Leu Pro Leu Val Gln Gln Gln Val Ala Pro Ser 
    130                 135                 140                 


Asp Lys Pro Pro Lys Pro Glu Leu Pro Gly Val Asp Phe Ala Asp Pro 
145                 150                 155                 160 


Gln Gly Pro Ser Leu Pro Gly Met Asp Phe Pro Asp Pro Gln Gly Pro 
                165                 170                 175     


Ser Leu Pro Gly Leu Asp Phe Ala Asp Pro Gln Gly Ser Thr Ile Phe 
            180                 185                 190         


Gln Ile Ala Arg Leu Ile Ser His Gly Pro Met Pro Gln Asn Lys Gln 
        195                 200                 205             


Ser Pro Leu Tyr Pro Gly Met Leu Tyr Val Pro Phe Gly Ala Asn Gln 
    210                 215                 220                 


Leu Asn Ala Pro Ala Arg Leu Gly Ile Met Ser Ser Glu Glu Val Ala 
225                 230                 235                 240 


Gly Gly Arg Glu Asp Pro Met Ala Tyr Gly Ala Met Phe Pro Gly Phe 
                245                 250                 255     


Gly Gly Met Arg Pro Gly Phe Glu Gly Met Pro His Asn Pro Ala Met 
            260                 265                 270         


Gly Gly Asp Phe Thr Leu Glu Phe Asp Ser Pro Val Ala Ala Thr Lys 
        275                 280                 285             


Gly Pro Glu Asn Glu Glu Gly Gly Ala Gln Gly Ser Pro Met Pro Glu 
    290                 295                 300                 


Ala Asn Pro Asp Asn Leu Glu Asn Pro Ala Phe Leu Thr Glu Leu Glu 
305                 310                 315                 320 


Pro Ala Pro His Ala Gly Leu Pro Ala Leu Pro Lys Asp Asp Ile Pro 
                325                 330                 335     


Gly Leu Pro Arg Ser Pro Ser Gly Lys Met Lys Gly Leu Pro Ser Val 
            340                 345                 350         


Thr Pro Ala Ala Ala Asp Pro Leu Met Thr Pro Glu Leu Ala Asp Val 
        355                 360                 365             


Tyr Arg Thr Tyr Asp Ala Asp Met Thr Thr Ser Val Asp Phe Gln Glu 
    370                 375                 380                 


Glu Ala Thr Met Asp Thr Thr Met Ala Pro Asn Ser Leu Gln Thr Ser 
385                 390                 395                 400 


Met Pro Gly Asn Lys Ala Gln Glu Pro Glu Met Met His Asp Ala Trp 
                405                 410                 415     


His Phe Gln Glu Pro 
            420     


<210>  2958
<211>  92
<212>  PRT
<213>  Homo Sapiens

<400>  2958

Tyr Gly Phe Lys Ala Thr Phe Asn Tyr Glu Asn Cys Leu Lys Lys Val 
1               5                   10                  15      


Ser Leu Leu Leu Thr Asn Thr Phe Asp Leu Glu Asp Gly Phe Leu Thr 
            20                  25                  30          


Ala Ser Asn Leu Glu Gln Val Lys Gly Tyr Leu Ala Ser Ala Tyr Pro 
        35                  40                  45              


Ser Lys Tyr Ser Glu Met Phe Pro Gln Ile Lys Asn Cys Ser Leu Glu 
    50                  55                  60                  


Ser Glu Leu Asp Thr Ala Val Gln Gly Thr Gly Leu Ala Phe Ile Val 
65                  70                  75                  80  


Tyr Thr Glu Ala Ile Lys Asn Met Glu Val Ser Gln 
                85                  90          


<210>  2959
<211>  136
<212>  PRT
<213>  Homo Sapiens

<400>  2959

Ser Glu Val Pro Gly Ala Ala Ala Glu Gly Ser Gly Gly Ser Gly Val 
1               5                   10                  15      


Gly Ile Gly Asp Arg Phe Lys Ile Glu Gly Arg Ala Val Val Pro Gly 
            20                  25                  30          


Val Lys Pro Gln Asp Trp Ile Ser Ala Ala Arg Val Leu Val Asp Gly 
        35                  40                  45              


Glu Glu His Val Gly Phe Leu Lys Thr Asp Gly Ser Phe Val Val His 
    50                  55                  60                  


Asp Ile Pro Ser Gly Ser Tyr Val Val Glu Val Val Ser Pro Ala Tyr 
65                  70                  75                  80  


Arg Phe Asp Pro Val Arg Val Asp Ile Thr Ser Lys Gly Lys Met Arg 
                85                  90                  95      


Ala Arg Tyr Val Asn Tyr Ile Lys Thr Ser Glu Val Val Arg Leu Pro 
            100                 105                 110         


Tyr Pro Leu Gln Met Lys Ser Ser Gly Pro Pro Ser Tyr Phe Ile Lys 
        115                 120                 125             


Arg Glu Ser Trp Gly Trp Thr Asp 
    130                 135     


<210>  2960
<211>  126
<212>  PRT
<213>  Homo Sapiens

<400>  2960

Lys Pro Phe Met Leu Ser Ile Gln Arg Glu Glu Ser Thr Cys Thr Ala 
1               5                   10                  15      


Ile His Thr Asp Ile Met Asp Asp Trp Leu Asp Cys Ala Phe Thr Cys 
            20                  25                  30          


Gly Val His Cys His Gly Gln Gly Lys Tyr Pro Cys Leu Gln Val Phe 
        35                  40                  45              


Val Asn Leu Ser His Pro Gly Gln Lys Ala Leu Leu His Tyr Asn Glu 
    50                  55                  60                  


Glu Ala Val Gln Ile Asn Pro Lys Cys Phe Tyr Thr Pro Lys Cys His 
65                  70                  75                  80  


Gln Asp Arg Asn Asp Leu Leu Asn Ser Ala Leu Asp Ile Lys Glu Phe 
                85                  90                  95      


Phe Asp His Lys Asn Gly Thr Pro Phe Ser Cys Phe Tyr Ser Pro Ala 
            100                 105                 110         


Ser Gln Ser Glu Asp Val Ile Leu Ile Lys Lys Tyr Asp Gln 
        115                 120                 125     


<210>  2961
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  2961

Phe Pro Leu Ile Cys Glu Ser Lys Ser Val Ala Gly Leu Thr Leu Thr 
1               5                   10                  15      


Tyr Asp Gly Asn Asn Ser Val Ala Ser His Val Asp Val Pro Leu Ser 
            20                  25                  30          


Tyr Cys Asn Ser Glu Cys Asn Cys Asp Glu Ser Gln Trp Glu Pro Val 
        35                  40                  45              


Cys Gly Asn Asn Gly Ile Thr Tyr Leu Ser Pro Cys Leu Ala Gly Cys 
    50                  55                  60                  


Lys Ser Ser Ser Gly Ile Lys Lys His Thr Val Phe Tyr Asn Cys Ser 
65                  70                  75                  80  


Cys Val Glu Val Thr Gly Leu Gln Asn Arg Asn Tyr Ser Ala His Leu 
                85                  90                  95      


Gly Glu Cys Pro Arg Asp Asn Thr Cys Thr Arg Lys Phe Phe Ile Tyr 
            100                 105                 110         


<210>  2962
<211>  215
<212>  PRT
<213>  Homo Sapiens

<400>  2962

Gly Gly Leu Leu Lys Tyr Gln Thr Asn Leu Asp Thr His Pro Pro Gly 
1               5                   10                  15      


Cys Ile Ser Leu Asn Arg Thr Ser Ser Gln Asn Ile Ser Leu Pro Glu 
            20                  25                  30          


Tyr Phe Ser Glu His Phe His Glu Pro Phe Pro Glu Gly Phe Ser Lys 
        35                  40                  45              


Pro Ala Glu Phe Thr Gln His Lys Phe Val Lys Ile Cys Met Glu Glu 
    50                  55                  60                  


Pro Arg Phe Gln Ala Asn Phe Pro Gln Thr Trp Leu Trp Ile Ser Gly 
65                  70                  75                  80  


Pro Leu Cys Leu Tyr Cys Ala Glu Arg Leu Tyr Arg Tyr Ile Arg Ser 
                85                  90                  95      


Asn Lys Pro Val Thr Ile Ile Ser Val Ile Ser His Pro Ser Asp Val 
            100                 105                 110         


Met Glu Ile Arg Met Val Lys Glu Asn Phe Lys Ala Arg Pro Gly Gln 
        115                 120                 125             


Tyr Ile Thr Leu His Cys Pro Ser Val Ser Ala Leu Glu Asn His Pro 
    130                 135                 140                 


Phe Thr Leu Thr Met Cys Pro Thr Glu Thr Lys Ala Thr Phe Gly Val 
145                 150                 155                 160 


His Leu Lys Ile Val Gly Asp Trp Thr Glu Arg Phe Arg Asp Leu Leu 
                165                 170                 175     


Leu Pro Pro Ser Ser Gln Asp Ser Glu Ile Leu Pro Phe Ile Gln Ser 
            180                 185                 190         


Arg Asn Tyr Pro Lys Leu Tyr Ile Asp Gly Pro Phe Gly Ser Pro Phe 
        195                 200                 205             


Glu Glu Ser Leu Asn Tyr Glu 
    210                 215 


<210>  2963
<211>  155
<212>  PRT
<213>  Homo Sapiens

<400>  2963

Leu Ser Phe Thr Leu Glu Glu Glu Asp Ile Thr Gly Thr Trp Tyr Val 
1               5                   10                  15      


Lys Ala Met Val Val Asp Lys Asp Phe Pro Glu Asp Arg Arg Pro Arg 
            20                  25                  30          


Lys Val Ser Pro Val Lys Val Thr Ala Leu Gly Gly Gly Lys Leu Glu 
        35                  40                  45              


Ala Thr Phe Thr Phe Met Arg Glu Asp Arg Cys Ile Gln Lys Lys Ile 
    50                  55                  60                  


Leu Met Arg Lys Thr Glu Glu Pro Gly Lys Tyr Ser Ala Tyr Gly Gly 
65                  70                  75                  80  


Arg Lys Leu Met Tyr Leu Gln Glu Leu Pro Arg Arg Asp His Tyr Ile 
                85                  90                  95      


Phe Tyr Cys Lys Asp Gln His His Gly Gly Leu Leu His Met Gly Lys 
            100                 105                 110         


Leu Val Gly Arg Asn Ser Asp Thr Asn Arg Glu Ala Leu Glu Glu Phe 
        115                 120                 125             


Lys Lys Leu Val Gln Arg Lys Gly Leu Ser Glu Glu Asp Ile Phe Thr 
    130                 135                 140                 


Pro Leu Gln Thr Gly Ser Cys Val Pro Glu His 
145                 150                 155 


<210>  2964
<211>  165
<212>  PRT
<213>  Homo Sapiens

<400>  2964

Trp Ser Asn Asn Tyr Ala Val Asp Cys Pro Gln His Cys Asp Ser Ser 
1               5                   10                  15      


Glu Cys Lys Ser Ser Pro Arg Cys Lys Arg Thr Val Leu Asp Asp Cys 
            20                  25                  30          


Gly Cys Cys Arg Val Cys Ala Ala Gly Arg Gly Glu Thr Cys Tyr Arg 
        35                  40                  45              


Thr Val Ser Gly Met Asp Gly Met Lys Cys Gly Pro Gly Leu Arg Cys 
    50                  55                  60                  


Gln Pro Ser Asn Gly Glu Asp Pro Phe Gly Glu Glu Phe Gly Ile Cys 
65                  70                  75                  80  


Lys Asp Cys Pro Tyr Gly Thr Phe Gly Met Asp Cys Arg Glu Thr Cys 
                85                  90                  95      


Asn Cys Gln Ser Gly Ile Cys Asp Arg Gly Thr Gly Lys Cys Leu Lys 
            100                 105                 110         


Phe Pro Phe Phe Gln Tyr Ser Val Thr Lys Ser Ser Asn Arg Phe Val 
        115                 120                 125             


Ser Leu Thr Glu His Asp Met Ala Ser Gly Asp Gly Asn Ile Val Arg 
    130                 135                 140                 


Glu Glu Val Val Lys Glu Asn Ala Ala Gly Ser Pro Val Met Arg Lys 
145                 150                 155                 160 


Trp Leu Asn Pro Arg 
                165 


<210>  2965
<211>  71
<212>  PRT
<213>  Homo Sapiens

<400>  2965

Ala Lys Asn Phe Glu Asp Val Arg Cys Lys Cys Ile Cys Pro Pro Tyr 
1               5                   10                  15      


Lys Glu Asn Ser Gly His Ile Tyr Asn Lys Asn Ile Ser Gln Lys Asp 
            20                  25                  30          


Cys Asp Cys Leu His Val Val Glu Pro Met Pro Val Arg Gly Pro Asp 
        35                  40                  45              


Val Glu Ala Tyr Cys Leu Arg Cys Glu Cys Lys Tyr Glu Glu Arg Ser 
    50                  55                  60                  


Ser Val Thr Ile Lys Val Thr 
65                  70      


<210>  2966
<211>  1042
<212>  PRT
<213>  Homo Sapiens

<400>  2966

Lys Asn Glu Asp Gln Glu Met Cys His Glu Phe Gln Ala Phe Met Lys 
1               5                   10                  15      


Asn Gly Lys Leu Phe Cys Pro Gln Asp Lys Lys Phe Phe Gln Ser Leu 
            20                  25                  30          


Asp Gly Ile Met Phe Ile Asn Lys Cys Ala Thr Cys Lys Met Ile Leu 
        35                  40                  45              


Glu Lys Glu Ala Lys Ser Gln Lys Arg Ala Arg His Leu Ala Arg Ala 
    50                  55                  60                  


Pro Lys Ala Thr Ala Pro Thr Glu Leu Asn Cys Asp Asp Phe Lys Lys 
65                  70                  75                  80  


Gly Glu Arg Asp Gly Asp Phe Ile Cys Pro Asp Tyr Tyr Glu Ala Val 
                85                  90                  95      


Cys Gly Thr Asp Gly Lys Thr Tyr Asp Asn Arg Cys Ala Leu Cys Ala 
            100                 105                 110         


Glu Asn Ala Lys Thr Gly Ser Gln Ile Gly Val Lys Ser Glu Gly Glu 
        115                 120                 125             


Cys Lys Ser Ser Asn Pro Glu Gln Asp Val Cys Ser Ala Phe Arg Pro 
    130                 135                 140                 


Phe Val Arg Asp Gly Arg Leu Gly Cys Thr Arg Glu Asn Asp Pro Val 
145                 150                 155                 160 


Leu Gly Pro Asp Gly Lys Thr His Gly Asn Lys Cys Ala Met Cys Ala 
                165                 170                 175     


Glu Leu Phe Leu Lys Glu Ala Glu Asn Ala Lys Arg Glu Gly Glu Thr 
            180                 185                 190         


Arg Ile Arg Arg Asn Ala Glu Lys Asp Phe Cys Lys Glu Tyr Glu Lys 
        195                 200                 205             


Gln Val Arg Asn Gly Arg Leu Phe Cys Thr Arg Glu Ser Asp Pro Val 
    210                 215                 220                 


Arg Gly Pro Asp Gly Arg Met His Gly Asn Lys Cys Ala Leu Cys Ala 
225                 230                 235                 240 


Glu Ile Phe Lys Gln Arg Phe Ser Glu Glu Asn Ser Lys Thr Asp Gln 
                245                 250                 255     


Asn Leu Gly Lys Ala Glu Glu Lys Thr Lys Val Lys Arg Glu Ile Val 
            260                 265                 270         


Lys Leu Cys Ser Gln Tyr Gln Asn Gln Ala Lys Asn Gly Ile Leu Phe 
        275                 280                 285             


Cys Thr Arg Glu Asn Asp Pro Ile Arg Gly Pro Asp Gly Lys Met His 
    290                 295                 300                 


Gly Asn Leu Cys Ser Met Cys Gln Ala Tyr Phe Gln Ala Glu Asn Glu 
305                 310                 315                 320 


Glu Lys Lys Lys Ala Glu Ala Arg Ala Arg Asn Lys Arg Glu Ser Gly 
                325                 330                 335     


Lys Ala Thr Ser Tyr Ala Glu Leu Cys Ser Glu Tyr Arg Lys Leu Val 
            340                 345                 350         


Arg Asn Gly Lys Leu Ala Cys Thr Arg Glu Asn Asp Pro Ile Gln Gly 
        355                 360                 365             


Pro Asp Gly Lys Val His Gly Asn Thr Cys Ser Met Cys Glu Val Phe 
    370                 375                 380                 


Phe Gln Ala Glu Glu Glu Glu Lys Lys Lys Lys Glu Gly Lys Ser Arg 
385                 390                 395                 400 


Asn Lys Arg Gln Ser Lys Ser Thr Ala Ser Phe Glu Glu Leu Cys Ser 
                405                 410                 415     


Glu Tyr Arg Lys Ser Arg Lys Asn Gly Arg Leu Phe Cys Thr Arg Glu 
            420                 425                 430         


Asn Asp Pro Ile Gln Gly Pro Asp Gly Lys Met His Gly Asn Thr Cys 
        435                 440                 445             


Ser Met Cys Glu Ala Phe Phe Gln Gln Glu Glu Arg Ala Arg Ala Lys 
    450                 455                 460                 


Ala Lys Arg Glu Ala Ala Lys Glu Ile Cys Ser Glu Phe Arg Asp Gln 
465                 470                 475                 480 


Val Arg Asn Gly Thr Leu Ile Cys Thr Arg Glu His Asn Pro Val Arg 
                485                 490                 495     


Gly Pro Asp Gly Lys Met His Gly Asn Lys Cys Ala Met Cys Ala Ser 
            500                 505                 510         


Val Phe Lys Leu Glu Glu Glu Glu Lys Lys Asn Asp Lys Glu Glu Lys 
        515                 520                 525             


Gly Lys Val Glu Ala Glu Lys Val Lys Arg Glu Ala Val Gln Glu Leu 
    530                 535                 540                 


Cys Ser Glu Tyr Arg His Tyr Val Arg Asn Gly Arg Leu Pro Cys Thr 
545                 550                 555                 560 


Arg Glu Asn Asp Pro Ile Glu Gly Leu Asp Gly Lys Ile His Gly Asn 
                565                 570                 575     


Thr Cys Ser Met Cys Glu Ala Phe Phe Gln Gln Glu Ala Lys Glu Lys 
            580                 585                 590         


Glu Arg Ala Glu Pro Arg Ala Lys Val Lys Arg Glu Ala Glu Lys Glu 
        595                 600                 605             


Thr Cys Asp Glu Phe Arg Arg Leu Leu Gln Asn Gly Lys Leu Phe Cys 
    610                 615                 620                 


Thr Arg Glu Asn Asp Pro Val Arg Gly Pro Asp Gly Lys Thr His Gly 
625                 630                 635                 640 


Asn Lys Cys Ala Met Cys Lys Ala Val Phe Gln Lys Glu Asn Glu Glu 
                645                 650                 655     


Arg Lys Arg Lys Glu Glu Glu Asp Gln Arg Asn Ala Ala Gly His Gly 
            660                 665                 670         


Ser Ser Gly Gly Gly Gly Gly Asn Thr Gln Asp Glu Cys Ala Glu Tyr 
        675                 680                 685             


Arg Glu Gln Met Lys Asn Gly Arg Leu Ser Cys Thr Arg Glu Ser Asp 
    690                 695                 700                 


Pro Val Arg Asp Ala Asp Gly Lys Ser Tyr Asn Asn Gln Cys Thr Met 
705                 710                 715                 720 


Cys Lys Ala Lys Leu Glu Arg Glu Ala Glu Arg Lys Asn Glu Tyr Ser 
                725                 730                 735     


Arg Ser Arg Ser Asn Gly Thr Gly Ser Glu Ser Gly Lys Asp Thr Cys 
            740                 745                 750         


Asp Glu Phe Arg Ser Gln Met Lys Asn Gly Lys Leu Ile Cys Thr Arg 
        755                 760                 765             


Glu Ser Asp Pro Val Arg Gly Pro Asp Gly Lys Thr His Gly Asn Lys 
    770                 775                 780                 


Cys Thr Met Cys Lys Glu Lys Leu Glu Arg Glu Ala Ala Glu Lys Lys 
785                 790                 795                 800 


Lys Lys Glu Asp Glu Asp Arg Ser Asn Thr Gly Glu Arg Ser Asn Thr 
                805                 810                 815     


Gly Glu Arg Ser Asn Asp Lys Glu Asp Leu Cys Arg Glu Phe Arg Ser 
            820                 825                 830         


Met Gln Arg Asn Gly Lys Leu Ile Cys Thr Arg Glu Asn Asn Pro Val 
        835                 840                 845             


Arg Gly Pro Tyr Gly Lys Met His Ile Asn Lys Cys Ala Met Cys Gln 
    850                 855                 860                 


Ser Ile Phe Asp Arg Glu Ala Asn Glu Arg Lys Lys Lys Asp Glu Glu 
865                 870                 875                 880 


Lys Ser Ser Ser Lys Pro Ser Asn Asn Ala Lys Asp Glu Cys Ser Glu 
                885                 890                 895     


Phe Arg Asn Tyr Ile Arg Asn Asn Glu Leu Ile Cys Pro Arg Glu Asn 
            900                 905                 910         


Asp Pro Val His Gly Ala Asp Gly Lys Phe Tyr Thr Asn Lys Cys Tyr 
        915                 920                 925             


Met Cys Arg Ala Val Phe Leu Thr Glu Ala Leu Glu Arg Ala Lys Leu 
    930                 935                 940                 


Gln Glu Lys Pro Ser His Val Arg Ala Ser Gln Glu Glu Asp Ser Pro 
945                 950                 955                 960 


Asp Ser Phe Ser Ser Leu Asp Ser Glu Met Cys Lys Asp Tyr Arg Val 
                965                 970                 975     


Leu Pro Arg Ile Gly Tyr Leu Cys Pro Lys Asp Leu Lys Pro Val Cys 
            980                 985                 990         


Gly Asp Asp Gly Gln Thr Tyr Asn  Asn Pro Cys Met Leu  Cys His Glu 
        995                 1000                 1005             


Asn Leu  Ile Arg Gln Thr Asn  Thr His Ile Arg Ser  Thr Gly Lys 
    1010                 1015                 1020             


Cys Glu  Glu Ser Ser Thr Pro  Gly Thr Thr Ala Ala  Ser Met Pro 
    1025                 1030                 1035             


Pro Ser  Asp Glu 
    1040         


<210>  2967
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  2967

Gln Gly Ser Gly Leu Thr Thr Cys Val Asn Val Thr Glu Ile Ser Asp 
1               5                   10                  15      


Ser Val Pro Ser Pro Val Pro Thr Arg Glu Thr Asp Ile Ala Gln Gly 
            20                  25                  30          


Val Pro Arg Ala Leu Val Ser Ala Leu Pro Gly Met Glu Ala Pro Leu 
        35                  40                  45              


Ser His Leu Glu Ser Arg Tyr Leu Pro Ala His Phe Ser Pro 
    50                  55                  60          


<210>  2968
<211>  167
<212>  PRT
<213>  Homo Sapiens

<400>  2968

Leu Lys Ser Ser Thr Leu Lys Pro Thr Ile Glu Ala Leu Pro Asn Val 
1               5                   10                  15      


Leu Pro Leu Asn Glu Asp Val Asn Lys Gln Glu Glu Lys Asn Glu Asp 
            20                  25                  30          


His Thr Pro Asn Tyr Ala Pro Ala Asn Glu Lys Asn Gly Asn Tyr Tyr 
        35                  40                  45              


Lys Asp Ile Lys Gln Tyr Val Phe Thr Thr Gln Asn Pro Asn Gly Thr 
    50                  55                  60                  


Glu Ser Glu Ile Ser Val Arg Ala Thr Thr Asp Leu Asn Phe Ala Leu 
65                  70                  75                  80  


Lys Asn Asp Lys Thr Val Asn Ala Thr Thr Tyr Glu Lys Ser Thr Ile 
                85                  90                  95      


Glu Glu Glu Thr Thr Thr Ser Glu Pro Ser His Lys Asn Ile Gln Arg 
            100                 105                 110         


Ser Thr Pro Asn Val Pro Ala Phe Trp Thr Met Leu Ala Lys Ala Ile 
        115                 120                 125             


Asn Gly Thr Ala Val Val Met Asp Asp Lys Asp Gln Leu Phe His Pro 
    130                 135                 140                 


Ile Pro Glu Ser Asp Val Asn Ala Thr Gln Gly Glu Asn Gln Pro Asp 
145                 150                 155                 160 


Leu Glu Asp Leu Lys Ile Lys 
                165         


<210>  2969
<211>  508
<212>  PRT
<213>  Homo Sapiens

<400>  2969

Pro Thr Phe Gln Pro Gln Thr Glu Lys Thr Lys Gln Ser Cys Val Glu 
1               5                   10                  15      


Glu Gln Arg Gln Glu Glu Lys Asn Lys Asp Asn Ile Gly Phe His His 
            20                  25                  30          


Leu Gly Lys Arg Ile Asn Gln Glu Leu Ser Ser Lys Glu Asn Ile Val 
        35                  40                  45              


Gln Glu Arg Lys Lys Asp Leu Ser Leu Ser Glu Ala Ser Glu Asn Lys 
    50                  55                  60                  


Gly Ser Ser Lys Ser Gln Asn Tyr Phe Thr Asn Arg Gln Arg Leu Asn 
65                  70                  75                  80  


Lys Glu Tyr Ser Ile Ser Asn Lys Glu Asn Thr His Asn Gly Leu Arg 
                85                  90                  95      


Met Ser Ile Tyr Pro Lys Ser Thr Gly Asn Lys Gly Phe Glu Asp Gly 
            100                 105                 110         


Asp Asp Ala Ile Ser Lys Leu His Asp Gln Glu Glu Tyr Gly Ala Ala 
        115                 120                 125             


Leu Ile Arg Asn Asn Met Gln His Ile Met Gly Pro Val Thr Ala Ile 
    130                 135                 140                 


Lys Leu Leu Gly Glu Glu Asn Lys Glu Asn Thr Pro Arg Asn Val Leu 
145                 150                 155                 160 


Asn Ile Ile Pro Ala Ser Met Asn Tyr Ala Lys Ala His Ser Lys Asp 
                165                 170                 175     


Lys Lys Lys Pro Gln Arg Asp Ser Gln Ala Gln Lys Ser Pro Val Lys 
            180                 185                 190         


Ser Lys Ser Thr His Arg Ile Gln His Asn Ile Asp Tyr Leu Lys His 
        195                 200                 205             


Leu Ser Lys Val Lys Lys Ile Pro Ser Asp Phe Glu Gly Ser Gly Tyr 
    210                 215                 220                 


Thr Asp Leu Gln Glu Arg Gly Asp Asn Asp Ile Ser Pro Phe Ser Gly 
225                 230                 235                 240 


Asp Gly Gln Pro Phe Lys Asp Ile Pro Gly Lys Gly Glu Ala Thr Gly 
                245                 250                 255     


Pro Asp Leu Glu Gly Lys Asp Ile Gln Thr Gly Phe Ala Gly Pro Ser 
            260                 265                 270         


Glu Ala Glu Ser Thr His Leu Asp Thr Lys Lys Pro Gly Tyr Asn Glu 
        275                 280                 285             


Ile Pro Glu Arg Glu Glu Asn Gly Gly Asn Thr Ile Gly Thr Arg Asp 
    290                 295                 300                 


Glu Thr Ala Lys Glu Ala Asp Ala Val Asp Val Ser Leu Val Glu Gly 
305                 310                 315                 320 


Ser Asn Asp Ile Met Gly Ser Thr Asn Phe Lys Glu Leu Pro Gly Arg 
                325                 330                 335     


Glu Gly Asn Arg Val Asp Ala Gly Ser Gln Asn Ala His Gln Gly Lys 
            340                 345                 350         


Val Glu Phe His Tyr Pro Pro Ala Pro Ser Lys Glu Lys Arg Lys Glu 
        355                 360                 365             


Gly Ser Ser Asp Ala Ala Glu Ser Thr Asn Tyr Asn Glu Ile Pro Lys 
    370                 375                 380                 


Asn Gly Lys Gly Ser Thr Arg Lys Gly Val Asp His Ser Asn Arg Asn 
385                 390                 395                 400 


Gln Ala Thr Leu Asn Glu Lys Gln Arg Phe Pro Ser Lys Gly Lys Ser 
                405                 410                 415     


Gln Gly Leu Pro Ile Pro Ser Arg Gly Leu Asp Asn Glu Ile Lys Asn 
            420                 425                 430         


Glu Met Asp Ser Phe Asn Gly Pro Ser His Glu Asn Ile Ile Thr His 
        435                 440                 445             


Gly Arg Lys Tyr His Tyr Val Pro His Arg Gln Asn Asn Ser Thr Arg 
    450                 455                 460                 


Asn Lys Gly Met Pro Gln Gly Lys Gly Ser Trp Gly Arg Gln Pro His 
465                 470                 475                 480 


Ser Asn Arg Arg Phe Ser Ser Arg Arg Arg Asp Asp Ser Ser Glu Ser 
                485                 490                 495     


Ser Asp Ser Gly Ser Ser Ser Glu Ser Asp Gly Asp 
            500                 505             


<210>  2970
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  2970

Phe Lys Gly Arg Phe Val Gly Arg Pro Gly Ser Tyr Val Tyr Val Phe 
1               5                   10                  15      


Asp Gly Tyr Arg Met Glu Glu Cys Ala Pro Gly Gly Cys Leu Met Glu 
            20                  25                  30          


Leu Cys Ile Gln Leu Ser Ile Ile Met Leu Gly Lys Gln Leu Ile Gln 
        35                  40                  45              


Asn Asn Ile Phe Glu Ile Gly Val Pro Lys Leu Lys Lys Leu Phe Arg 
    50                  55                  60                  


Lys Leu Lys Asp Glu Thr Glu Ala Gly Glu Thr Asp Ser Ala His Ser 
65                  70                  75                  80  


Lys His Pro Glu Gln Trp Asp Leu Asp Tyr Ser Leu Glu Pro Tyr Thr 
                85                  90                  95      


Gly Leu Thr Pro Glu Tyr Met Glu 
            100                 


<210>  2971
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  2971

Ser Leu Leu Arg Arg Leu Gly Glu His Ile Gln Gln Phe Gln Glu Ser 
1               5                   10                  15      


Ser Ala Gln Gly Leu Gly Leu Ser Leu Gly Pro Gly Ala Ala Ala Leu 
            20                  25                  30          


Pro Lys Val Gly Trp Leu Glu Gln Leu Leu Asp Pro Phe Asn Val Ser 
        35                  40                  45              


Asp Arg Arg Ser Phe Leu Gln Arg Tyr Trp Val Asn Asp Gln His Trp 
    50                  55                  60                  


Val Gly Gln Asp Gly Pro Ile Phe Leu His Leu Gly Gly Glu Gly Ser 
65                  70                  75                  80  


Leu Gly Pro Gly Ser Val Met Arg Gly His Pro Ala Ala Leu Ala Pro 
                85                  90                  95      


Ala Trp Gly Ala Leu Val Ile Ser Leu Glu His Arg Phe Tyr Gly Leu 
            100                 105                 110         


Ser Ile Pro Ala Gly Gly Leu Glu Met Ala Gln Leu Arg Phe Leu Ser 
        115                 120                 125             


Ser Arg Leu Ala Leu Ala Asp Val Val Ser Ala Arg Leu Ala Leu Ser 
    130                 135                 140                 


Arg Leu Phe Asn Ile Ser Ser Ser Ser Pro Trp Ile Cys Phe Gly Gly 
145                 150                 155                 160 


Ser Tyr Ala Gly Ser Leu Ala Ala Trp Ala Arg Leu Lys Phe Pro His 
                165                 170                 175     


Leu Ile Phe Ala Ser Val Ala Ser Ser Ala Pro Val Arg Ala Val Leu 
            180                 185                 190         


Asp Phe Ser Glu Tyr Asn Asp Val Val Ser Arg Ser Leu Met Ser Thr 
        195                 200                 205             


Ala Ile Gly Gly Ser Leu Glu Cys Arg Ala Ala Val Ser Val Ala Phe 
    210                 215                 220                 


Ala Glu Val Glu Arg Arg Leu Arg Ser Gly Gly Ala Ala Gln Ala Ala 
225                 230                 235                 240 


Leu Arg Thr Glu Leu Ser Ala Cys Gly Pro Leu Gly Arg Ala Glu Asn 
                245                 250                 255     


Gln Ala Glu Leu Leu Gly Ala Leu Gln Ala Leu Val Gly Gly Val Val 
            260                 265                 270         


Gln Tyr Asp Gly Gln Thr Gly Ala Pro Leu Ser Val Arg Gln Leu Cys 
        275                 280                 285             


Gly Leu Leu Leu Gly Gly Gly Gly Asn Arg Ser His Ser Thr Pro Tyr 
    290                 295                 300                 


Cys Gly Leu Arg Arg Ala Val Gln Ile Val Leu His Ser Leu Gly Gln 
305                 310                 315                 320 


Lys Cys Leu Ser Phe Ser Arg Ala Glu Thr Val Ala Gln Leu Arg Ser 
                325                 330                 335     


Thr Glu Pro Gln Leu Ser Gly Val Gly Asp Arg Gln Trp Leu Tyr Gln 
            340                 345                 350         


Thr Cys Thr Glu Phe Gly Phe Tyr Val Thr Cys Glu Asn Pro Arg Cys 
        355                 360                 365             


Pro Phe Ser Gln Leu Pro Ala Leu Pro Ser Gln Leu Asp Leu Cys Glu 
    370                 375                 380                 


Gln Val Phe Gly Leu Ser Ala Leu Ser Val Ala Gln Ala Val Ala Gln 
385                 390                 395                 400 


Thr Asn Ser Tyr Tyr Gly Gly Gln Thr Pro Gly Ala Asn Lys Val Leu 
                405                 410                 415     


Phe Val Asn Gly Asp Thr Asp Pro Trp His Val Leu Ser Val Thr Gln 
            420                 425                 430         


Ala Leu Gly Ser Ser Glu Ser Thr Leu Leu Ile Arg Thr Gly Ser His 
        435                 440                 445             


Cys Leu Asp Met Ala Pro Glu Arg Pro Ser Asp Ser Pro Ser Leu Arg 
    450                 455                 460                 


Leu Gly Arg Gln Asn Ile Phe Gln Gln Leu Gln Thr Trp Leu Lys Leu 
465                 470                 475                 480 


Ala Lys Glu Ser Gln Ile Lys Gly Glu Val 
                485                 490 


<210>  2972
<211>  147
<212>  PRT
<213>  Homo Sapiens

<400>  2972

Gly His Pro Asp Val Ala Ala Cys Pro Gly Ser Leu Asp Cys Ala Leu 
1               5                   10                  15      


Lys Arg Arg Ala Arg Cys Pro Pro Gly Ala His Ala Cys Gly Pro Cys 
            20                  25                  30          


Leu Gln Pro Phe Gln Glu Asp Gln Gln Gly Leu Cys Val Pro Arg Met 
        35                  40                  45              


Arg Arg Pro Pro Gly Gly Gly Arg Pro Gln Pro Arg Leu Glu Asp Glu 
    50                  55                  60                  


Ile Asp Phe Leu Ala Gln Glu Leu Ala Arg Lys Glu Ser Gly His Ser 
65                  70                  75                  80  


Thr Pro Pro Leu Pro Lys Asp Arg Gln Arg Leu Pro Glu Pro Ala Thr 
                85                  90                  95      


Leu Gly Phe Ser Ala Arg Gly Gln Gly Leu Glu Leu Gly Leu Pro Ser 
            100                 105                 110         


Thr Pro Gly Thr Pro Thr Pro Thr Pro His Thr Ser Leu Gly Ser Pro 
        115                 120                 125             


Val Ser Ser Asp Pro Val His Met Ser Pro Leu Glu Pro Arg Gly Gly 
    130                 135                 140                 


Gln Gly Asp 
145         


<210>  2973
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  2973

Val His Gly Ile Phe Met Asp Arg Leu Ala Ser Lys Lys Leu Cys Ala 
1               5                   10                  15      


Asp Asp Glu Cys Val Tyr Thr Ile Ser Leu Ala Ser Ala Gln Glu Asp 
            20                  25                  30          


Tyr Asn Ala Pro Asp Cys Arg Phe Ile Asn Val Lys Lys Gly Gln Gln 
        35                  40                  45              


Ile Tyr Val Tyr Ser Lys Leu Val Lys Glu Asn Gly Ala Gly Glu Phe 
    50                  55                  60                  


Trp Ala Gly Ser Val Tyr Gly Asp Gly Gln Asp Glu Met Gly Val Val 
65                  70                  75                  80  


Gly Tyr Phe Pro Arg Asn Leu Val Lys Glu Gln Arg Val Tyr Gln Glu 
                85                  90                  95      


Ala Thr Lys Glu Val Pro Thr Thr Asp Ile Asp Phe Phe Cys Glu 
            100                 105                 110     


<210>  2974
<211>  172
<212>  PRT
<213>  Homo Sapiens

<400>  2974

Thr Ser Ile Ser Pro Gly Arg Cys Lys Trp Asn Lys His Thr Leu Thr 
1               5                   10                  15      


Tyr Arg Ile Ile Asn Tyr Pro His Asp Met Lys Pro Ser Ala Val Lys 
            20                  25                  30          


Asp Ser Ile Tyr Asn Ala Val Ser Ile Trp Ser Asn Val Thr Pro Leu 
        35                  40                  45              


Ile Phe Gln Gln Val Gln Asn Gly Asp Ala Asp Ile Lys Val Ser Phe 
    50                  55                  60                  


Trp Gln Trp Ala His Glu Asp Gly Trp Pro Phe Asp Gly Pro Gly Gly 
65                  70                  75                  80  


Ile Leu Gly His Ala Phe Leu Pro Asn Ser Gly Asn Pro Gly Val Val 
                85                  90                  95      


His Phe Asp Lys Asn Glu His Trp Ser Ala Ser Asp Thr Gly Tyr Asn 
            100                 105                 110         


Leu Phe Leu Val Ala Thr His Glu Ile Gly His Ser Leu Gly Leu Gln 
        115                 120                 125             


His Ser Gly Asn Gln Ser Ser Ile Met Tyr Pro Thr Tyr Trp Tyr His 
    130                 135                 140                 


Asp Pro Arg Thr Phe Gln Leu Ser Ala Asp Asp Ile Gln Arg Ile Gln 
145                 150                 155                 160 


His Leu Tyr Gly Glu Lys Cys Ser Ser Asp Ile Pro 
                165                 170         


<210>  2975
<211>  1103
<212>  PRT
<213>  Homo Sapiens

<400>  2975

Met Pro Met His Met Pro Arg Met Pro Gly Phe Ser Ser Lys Ser Glu 
1               5                   10                  15      


Glu Met Met Arg Tyr Asn Gln Phe Asn Phe Met Asn Gly Pro His Met 
            20                  25                  30          


Ala His Leu Gly Pro Phe Phe Gly Asn Gly Leu Pro Gln Gln Phe Pro 
        35                  40                  45              


Gln Tyr Gln Met Pro Met Trp Pro Gln Pro Pro Pro Asn Thr Trp His 
    50                  55                  60                  


Pro Arg Lys Ser Ser Ala Pro Lys Arg His Asn Lys Thr Asp Gln Thr 
65                  70                  75                  80  


Gln Glu Thr Gln Lys Pro Asn Gln Thr Gln Ser Lys Lys Pro Pro Gln 
                85                  90                  95      


Lys Arg Pro Leu Lys Gln Pro Ser His Asn Gln Pro Gln Pro Glu Glu 
            100                 105                 110         


Glu Ala Gln Pro Pro Gln Ala Phe Pro Pro Phe Gly Asn Gly Leu Phe 
        115                 120                 125             


Pro Tyr Gln Gln Pro Pro Trp Gln Ile Pro Gln Arg Leu Pro Pro Pro 
    130                 135                 140                 


Gly Tyr Gly Arg Pro Pro Ile Ser Asn Glu Glu Gly Gly Asn Pro Tyr 
145                 150                 155                 160 


Phe Gly Tyr Phe Gly Tyr His Gly Phe Gly Gly Arg Pro Pro Tyr Tyr 
                165                 170                 175     


Ser Glu Glu Met Phe Glu Gln Asp Phe Glu Lys Pro Lys Glu Glu Asp 
            180                 185                 190         


Pro Pro Lys Ala Glu Ser Pro Gly Thr Glu Pro Thr Ala Asn Ser Thr 
        195                 200                 205             


Val Thr Glu Thr Asn Ser Thr Gln Pro Asn Pro Lys Gly Ser Gln Gly 
    210                 215                 220                 


Gly Asn Asp Thr Ser Pro Thr Gly Asn Ser Thr Pro Gly Leu Asn Thr 
225                 230                 235                 240 


Gly Asn Asn Pro Pro Ala Gln Asn Gly Ile Gly Pro Leu Pro Ala Val 
                245                 250                 255     


Asn Ala Ser Gly Gln Gly Gly Pro Gly Ser Gln Ile Pro Trp Arg Pro 
            260                 265                 270         


Ser Gln Pro Asn Ile Arg Glu Asn His Pro Tyr Pro Asn Ile Arg Asn 
        275                 280                 285             


Phe Pro Ser Gly Arg Gln Trp Tyr Phe Thr Gly Thr Val Met Gly His 
    290                 295                 300                 


Arg Gln Asn Arg Pro Phe Tyr Arg Asn Gln Gln Val Gln Arg Gly Pro 
305                 310                 315                 320 


Arg Trp Asn Phe Phe Ala Trp Glu Arg Lys Gln Val Ala Arg Pro Gly 
                325                 330                 335     


Asn Pro Val Tyr His Lys Ala Tyr Pro Pro Thr Ser Arg Gly Asn Tyr 
            340                 345                 350         


Pro Asn Tyr Ala Gly Asn Pro Ala Asn Leu Arg Arg Lys Pro Gln Gly 
        355                 360                 365             


Pro Asn Lys His Pro Val Gly Thr Thr Val Ala Pro Leu Gly Pro Lys 
    370                 375                 380                 


Pro Gly Pro Val Val Arg Asn Glu Lys Ile Gln Asn Pro Lys Glu Lys 
385                 390                 395                 400 


Pro Leu Gly Pro Lys Glu Gln Ile Ile Val Pro Thr Lys Asn Pro Thr 
                405                 410                 415     


Ser Pro Trp Arg Asn Ser Gln Gln Tyr Glu Val Asn Lys Ser Asn Tyr 
            420                 425                 430         


Lys Leu Pro His Ser Glu Gly Tyr Met Pro Val Pro Asn Phe Asn Ser 
        435                 440                 445             


Val Asp Gln His Glu Asn Ser Tyr Tyr Pro Arg Gly Asp Ser Arg Lys 
    450                 455                 460                 


Val Pro Asn Ser Asp Gly Gln Thr Gln Ser Gln Asn Leu Pro Lys Gly 
465                 470                 475                 480 


Ile Val Leu Gly Ser Arg Arg Met Pro Tyr Glu Ser Glu Thr Asn Gln 
                485                 490                 495     


Ser Glu Leu Lys His Ser Ser Tyr Gln Pro Ala Val Tyr Pro Glu Glu 
            500                 505                 510         


Ile Pro Ser Pro Ala Lys Glu His Phe Pro Ala Gly Arg Asn Thr Trp 
        515                 520                 525             


Asp His Gln Glu Ile Ser Pro Pro Phe Lys Glu Asp Pro Gly Arg Gln 
    530                 535                 540                 


Glu Glu His Leu Pro His Pro Ser His Gly Ser Arg Gly Ser Val Phe 
545                 550                 555                 560 


Tyr Pro Glu Tyr Asn Pro Tyr Asp Pro Arg Glu Asn Ser Pro Tyr Leu 
                565                 570                 575     


Arg Gly Asn Thr Trp Asp Glu Arg Asp Asp Ser Pro Asn Thr Met Gly 
            580                 585                 590         


Gln Lys Glu Ser Pro Leu Tyr Pro Ile Asn Thr Pro Asp Gln Lys Glu 
        595                 600                 605             


Ile Val Pro Tyr Asn Glu Glu Asp Pro Val Asp Pro Thr Gly Asp Glu 
    610                 615                 620                 


Val Phe Pro Gly Gln Asn Arg Trp Gly Glu Glu Leu Ser Phe Lys Gly 
625                 630                 635                 640 


Gly Pro Thr Val Arg His Tyr Glu Gly Glu Gln Tyr Thr Ser Asn Gln 
                645                 650                 655     


Pro Lys Glu Tyr Leu Pro Tyr Ser Leu Asp Asn Pro Ser Lys Pro Arg 
            660                 665                 670         


Glu Asp Phe Tyr Tyr Ser Glu Phe Tyr Pro Trp Ser Pro Asp Glu Asn 
        675                 680                 685             


Phe Pro Ser Tyr Asn Thr Ala Ser Thr Met Pro Pro Pro Ile Glu Ser 
    690                 695                 700                 


Arg Gly Tyr Tyr Val Asn Asn Ala Ala Gly Pro Glu Glu Ser Thr Leu 
705                 710                 715                 720 


Phe Pro Ser Arg Asn Ser Trp Asp His Arg Ile Gln Ala Gln Gly Gln 
                725                 730                 735     


Arg Glu Arg Arg Pro Tyr Phe Asn Arg Asn Ile Trp Asp Gln Ala Thr 
            740                 745                 750         


His Leu Gln Lys Ala Pro Ala Arg Pro Pro Asp Gln Lys Gly Asn Gln 
        755                 760                 765             


Pro Tyr Tyr Ser Asn Thr Pro Ala Gly Leu Gln Lys Asn Pro Ile Trp 
    770                 775                 780                 


His Glu Gly Glu Asn Leu Asn Tyr Gly Met Gln Ile Thr Arg Met Asn 
785                 790                 795                 800 


Ser Pro Glu Arg Glu His Ser Ser Phe Pro Asn Phe Ile Pro Pro Ser 
                805                 810                 815     


Tyr Pro Ser Gly Gln Lys Glu Ala His Leu Phe His Leu Ser Gln Arg 
            820                 825                 830         


Gly Ser Cys Cys Ala Gly Ser Ser Thr Gly Pro Lys Asp Asn Pro Leu 
        835                 840                 845             


Ala Leu Gln Asp Tyr Thr Pro Ser Tyr Gly Leu Ala Pro Gly Glu Asn 
    850                 855                 860                 


Gln Asp Thr Ser Pro Leu Tyr Thr Asp Gly Ser His Thr Lys Gln Thr 
865                 870                 875                 880 


Arg Asp Ile Ile Ser Pro Thr Ser Ile Leu Pro Gly Gln Arg Asn Ser 
                885                 890                 895     


Ser Glu Lys Arg Glu Ser Gln Asn Pro Phe Arg Asp Asp Val Ser Thr 
            900                 905                 910         


Leu Arg Arg Asn Thr Pro Cys Ser Ile Lys Asn Gln Leu Gly Gln Lys 
        915                 920                 925             


Glu Ile Met Pro Phe Pro Glu Ala Ser Ser Leu Gln Ser Lys Asn Thr 
    930                 935                 940                 


Pro Cys Leu Lys Asn Asp Leu Gly Gly Asp Gly Asn Asn Ile Leu Glu 
945                 950                 955                 960 


Gln Val Phe Glu Asp Asn Gln Leu Asn Glu Arg Thr Val Asp Leu Thr 
                965                 970                 975     


Pro Glu Gln Leu Val Ile Gly Thr Pro Asp Glu Gly Ser Asn Pro Glu 
            980                 985                 990         


Gly Ile Gln Ser Gln Val Gln Glu  Asn Glu Ser Glu Arg  Gln Gln Gln 
        995                 1000                 1005             


Arg Pro  Ser Asn Ile Leu His  Leu Pro Cys Phe Gly  Ser Lys Leu 
    1010                 1015                 1020             


Ala Lys  His His Ser Ser Thr  Thr Gly Thr Pro Ser  Ser Asp Gly 
    1025                 1030                 1035             


Arg Gln  Ser Pro Phe Asp Gly  Asp Ser Ile Thr Pro  Thr Glu Asn 
    1040                 1045                 1050             


Pro Asn  Thr Leu Val Glu Leu  Ala Thr Glu Glu Gln  Phe Lys Ser 
    1055                 1060                 1065             


Ile Asn  Val Asp Pro Leu Asp  Ala Asp Glu His Ser  Pro Phe Glu 
    1070                 1075                 1080             


Phe Leu  Gln Arg Gly Thr Asn  Val Gln Asp Gln Val  Gln Asp Cys 
    1085                 1090                 1095             


Leu Leu  Leu Gln Ala 
    1100             


<210>  2976
<211>  385
<212>  PRT
<213>  Homo Sapiens

<400>  2976

Gln Gln His His Leu Val Glu Tyr Met Glu Arg Arg Leu Ala Ala Leu 
1               5                   10                  15      


Glu Glu Arg Leu Ala Gln Cys Gln Asp Gln Ser Ser Arg His Ala Ala 
            20                  25                  30          


Glu Leu Arg Asp Phe Lys Asn Lys Met Leu Pro Leu Leu Glu Val Ala 
        35                  40                  45              


Glu Lys Glu Arg Glu Ala Leu Arg Thr Glu Ala Asp Thr Ile Ser Gly 
    50                  55                  60                  


Arg Val Asp Arg Leu Glu Arg Glu Val Asp Tyr Leu Glu Thr Gln Asn 
65                  70                  75                  80  


Pro Ala Leu Pro Cys Val Glu Phe Asp Glu Lys Val Thr Gly Gly Pro 
                85                  90                  95      


Gly Thr Lys Gly Lys Gly Arg Arg Asn Glu Lys Tyr Asp Met Val Thr 
            100                 105                 110         


Asp Cys Gly Tyr Thr Ile Ser Gln Val Arg Ser Met Lys Ile Leu Lys 
        115                 120                 125             


Arg Phe Gly Gly Pro Ala Gly Leu Trp Thr Lys Asp Pro Leu Gly Gln 
    130                 135                 140                 


Thr Glu Lys Ile Tyr Val Leu Asp Gly Thr Gln Asn Asp Thr Ala Phe 
145                 150                 155                 160 


Val Phe Pro Arg Leu Arg Asp Phe Thr Leu Ala Met Ala Ala Arg Lys 
                165                 170                 175     


Ala Ser Arg Val Arg Val Pro Phe Pro Trp Val Gly Thr Gly Gln Leu 
            180                 185                 190         


Val Tyr Gly Gly Phe Leu Tyr Phe Ala Arg Arg Pro Pro Gly Arg Pro 
        195                 200                 205             


Gly Gly Gly Gly Glu Met Glu Asn Thr Leu Gln Leu Ile Lys Phe His 
    210                 215                 220                 


Leu Ala Asn Arg Thr Val Val Asp Ser Ser Val Phe Pro Ala Glu Gly 
225                 230                 235                 240 


Leu Ile Pro Pro Tyr Gly Leu Thr Ala Asp Thr Tyr Ile Asp Leu Ala 
                245                 250                 255     


Ala Asp Glu Glu Gly Leu Trp Ala Val Tyr Ala Thr Arg Glu Asp Asp 
            260                 265                 270         


Arg His Leu Cys Leu Ala Lys Leu Asp Pro Gln Thr Leu Asp Thr Glu 
        275                 280                 285             


Gln Gln Trp Asp Thr Pro Cys Pro Arg Glu Asn Ala Glu Ala Ala Phe 
    290                 295                 300                 


Val Ile Cys Gly Thr Leu Tyr Val Val Tyr Asn Thr Arg Pro Ala Ser 
305                 310                 315                 320 


Arg Ala Arg Ile Gln Cys Ser Phe Asp Ala Ser Gly Thr Leu Thr Pro 
                325                 330                 335     


Glu Arg Ala Ala Leu Pro Tyr Phe Pro Arg Arg Tyr Gly Ala His Ala 
            340                 345                 350         


Ser Leu Arg Tyr Asn Pro Arg Glu Arg Gln Leu Tyr Ala Trp Asp Asp 
        355                 360                 365             


Gly Tyr Gln Ile Val Tyr Lys Leu Glu Met Arg Lys Lys Glu Glu Glu 
    370                 375                 380                 


Val 
385 


<210>  2977
<211>  114
<212>  PRT
<213>  Homo Sapiens

<400>  2977

Thr Pro Pro Thr Cys Tyr Ser Arg Met Arg Ala Leu Ser Gln Glu Ile 
1               5                   10                  15      


Thr Arg Asp Phe Asn Leu Leu Gln Val Ser Glu Pro Ser Glu Pro Cys 
            20                  25                  30          


Val Arg Tyr Leu Pro Arg Leu Tyr Leu Asp Ile His Asn Tyr Cys Val 
        35                  40                  45              


Leu Asp Lys Leu Arg Asp Phe Val Ala Ser Pro Pro Cys Trp Lys Val 
    50                  55                  60                  


Ala Gln Val Asp Ser Leu Lys Asp Lys Ala Arg Lys Leu Tyr Thr Ile 
65                  70                  75                  80  


Met Asn Ser Phe Cys Arg Arg Asp Leu Val Phe Leu Leu Asp Asp Cys 
                85                  90                  95      


Asn Ala Leu Glu Tyr Pro Ile Pro Val Thr Thr Val Leu Pro Asp Arg 
            100                 105                 110         


Gln Arg 
        


<210>  2978
<211>  384
<212>  PRT
<213>  Homo Sapiens

<400>  2978

Lys Val Ile Leu Asp Lys Tyr Tyr Phe Leu Cys Gly Gln Pro Leu His 
1               5                   10                  15      


Phe Ile Pro Arg Lys Gln Leu Cys Asp Gly Glu Leu Asp Cys Pro Leu 
            20                  25                  30          


Gly Glu Asp Glu Glu His Cys Val Lys Ser Phe Pro Glu Gly Pro Ala 
        35                  40                  45              


Val Ala Val Arg Leu Ser Lys Asp Arg Ser Thr Leu Gln Val Leu Asp 
    50                  55                  60                  


Ser Ala Thr Gly Asn Trp Phe Ser Ala Cys Phe Asp Asn Phe Thr Glu 
65                  70                  75                  80  


Ala Leu Ala Glu Thr Ala Cys Arg Gln Met Gly Tyr Ser Ser Lys Pro 
                85                  90                  95      


Thr Phe Arg Ala Val Glu Ile Gly Pro Asp Gln Asp Leu Asp Val Val 
            100                 105                 110         


Glu Ile Thr Glu Asn Ser Gln Glu Leu Arg Met Arg Asn Ser Ser Gly 
        115                 120                 125             


Pro Cys Leu Ser Gly Ser Leu Val Ser Leu His Cys Leu Ala Cys Gly 
    130                 135                 140                 


Lys Ser Leu Lys Thr Pro Arg Val Val Gly Gly Glu Glu Ala Ser Val 
145                 150                 155                 160 


Asp Ser Trp Pro Trp Gln Val Ser Ile Gln Tyr Asp Lys Gln His Val 
                165                 170                 175     


Cys Gly Gly Ser Ile Leu Asp Pro His Trp Val Leu Thr Ala Ala His 
            180                 185                 190         


Cys Phe Arg Lys His Thr Asp Val Phe Asn Trp Lys Val Arg Ala Gly 
        195                 200                 205             


Ser Asp Lys Leu Gly Ser Phe Pro Ser Leu Ala Val Ala Lys Ile Ile 
    210                 215                 220                 


Ile Ile Glu Phe Asn Pro Met Tyr Pro Lys Asp Asn Asp Ile Ala Leu 
225                 230                 235                 240 


Met Lys Leu Gln Phe Pro Leu Thr Phe Ser Gly Thr Val Arg Pro Ile 
                245                 250                 255     


Cys Leu Pro Phe Phe Asp Glu Glu Leu Thr Pro Ala Thr Pro Leu Trp 
            260                 265                 270         


Ile Ile Gly Trp Gly Phe Thr Lys Gln Asn Gly Gly Lys Met Ser Asp 
        275                 280                 285             


Ile Leu Leu Gln Ala Ser Val Gln Val Ile Asp Ser Thr Arg Cys Asn 
    290                 295                 300                 


Ala Asp Asp Ala Tyr Gln Gly Glu Val Thr Glu Lys Met Met Cys Ala 
305                 310                 315                 320 


Gly Ile Pro Glu Gly Gly Val Asp Thr Cys Gln Gly Asp Ser Gly Gly 
                325                 330                 335     


Pro Leu Met Tyr Gln Ser Asp Gln Trp His Val Val Gly Ile Val Ser 
            340                 345                 350         


Trp Gly Tyr Gly Cys Gly Gly Pro Ser Thr Pro Gly Val Tyr Thr Lys 
        355                 360                 365             


Val Ser Ala Tyr Leu Asn Trp Ile Tyr Asn Val Trp Lys Ala Glu Leu 
    370                 375                 380                 


<210>  2979
<211>  165
<212>  PRT
<213>  Homo Sapiens

<400>  2979

Asn Tyr Asn Ile Asn Val Asn Asp Asp Asn Asn Asn Ala Gly Ser Gly 
1               5                   10                  15      


Gln Gln Ser Val Ser Val Asn Asn Glu His Asn Val Ala Asn Val Asp 
            20                  25                  30          


Asn Asn Asn Gly Trp Asp Ser Trp Asn Ser Ile Trp Asp Tyr Gly Asn 
        35                  40                  45              


Gly Phe Ala Ala Thr Arg Leu Phe Gln Lys Lys Thr Cys Ile Val His 
    50                  55                  60                  


Lys Met Asn Lys Glu Val Met Pro Ser Ile Gln Ser Leu Asp Ala Leu 
65                  70                  75                  80  


Val Lys Glu Lys Lys Leu Gln Gly Lys Gly Pro Gly Gly Pro Pro Pro 
                85                  90                  95      


Lys Gly Leu Met Tyr Ser Val Asn Pro Asn Lys Val Asp Asp Leu Ser 
            100                 105                 110         


Lys Phe Gly Lys Asn Ile Ala Asn Met Cys Arg Gly Ile Pro Thr Tyr 
        115                 120                 125             


Met Ala Glu Glu Met Gln Glu Ala Ser Leu Phe Phe Tyr Ser Gly Thr 
    130                 135                 140                 


Cys Tyr Thr Thr Ser Val Leu Trp Ile Val Asp Ile Ser Phe Cys Gly 
145                 150                 155                 160 


Asp Thr Val Glu Asn 
                165 


<210>  2980
<211>  111
<212>  PRT
<213>  Homo Sapiens

<400>  2980

Pro Ser Gln Met Leu Leu Glu Asn Phe Ser Ala Ala Ile Pro Gly His 
1               5                   10                  15      


Arg Cys Trp Thr His Met Leu Asp Asn Gly Ser Ala Val Ser Thr Asn 
            20                  25                  30          


Met Thr Pro Lys Ala Leu Leu Thr Ile Ser Ile Pro Pro Gly Pro Asn 
        35                  40                  45              


Gln Gly Pro His Gln Cys Arg Arg Phe Arg Gln Pro Gln Trp Gln Leu 
    50                  55                  60                  


Leu Asp Pro Asn Ala Thr Ala Thr Ser Trp Ser Glu Ala Asp Thr Glu 
65                  70                  75                  80  


Pro Cys Val Asp Gly Trp Val Tyr Asp Arg Ser Val Phe Thr Ser Thr 
                85                  90                  95      


Ile Val Ala Lys Trp Asp Leu Val Cys Ser Ser Gln Gly Leu Lys 
            100                 105                 110     


<210>  2981
<211>  65
<212>  PRT
<213>  Homo Sapiens

<400>  2981

Ser Ser Phe Thr Ile Asp Leu Pro Trp Gly Gly Cys Tyr His Glu Trp 
1               5                   10                  15      


Asn Thr Glu His Cys Met Glu Phe Gln Lys Thr Asn Gly Ser Leu Asn 
            20                  25                  30          


Gly Thr Ser Glu Asn Ala Thr Ser Pro Val Ile Glu Phe Trp Glu Arg 
        35                  40                  45              


Arg Val Leu Lys Ile Ser Asp Gly Ile Gln His Leu Gly Ala Leu Arg 
    50                  55                  60                  


Trp 
65  


<210>  2982
<211>  744
<212>  PRT
<213>  Homo Sapiens

<400>  2982

Arg Gly Thr Pro Leu Leu Ala Arg Pro Ala Pro Pro Gly Ala Ser Arg 
1               5                   10                  15      


Tyr Ser Leu Tyr Thr Thr Gly Trp Arg Pro Arg Leu Arg Pro Gly Pro 
            20                  25                  30          


His Lys Ala Leu Cys Ala Tyr Val Val His Arg Asn Val Thr Cys Ile 
        35                  40                  45              


Leu Gln Glu Gly Ala Glu Ser Tyr Val Lys Ala Glu Tyr Arg Gln Cys 
    50                  55                  60                  


Arg Trp Gly Pro Lys Cys Pro Gly Thr Val Thr Tyr Arg Thr Val Leu 
65                  70                  75                  80  


Arg Pro Lys Tyr Lys Val Gly Tyr Lys Thr Val Thr Asp Leu Ala Trp 
                85                  90                  95      


Arg Cys Cys Pro Gly Phe Thr Gly Lys Arg Cys Pro Glu His Leu Thr 
            100                 105                 110         


Asp His Gly Ala Ala Ser Pro Gln Leu Glu Pro Glu Pro Gln Ile Pro 
        115                 120                 125             


Ser Gly Gln Leu Asp Pro Gly Pro Arg Pro Pro Ser Tyr Ser Arg Ala 
    130                 135                 140                 


Ala Pro Ser Pro His Gly Arg Lys Gly Pro Gly Leu Phe Gly Glu Arg 
145                 150                 155                 160 


Leu Glu Arg Leu Glu Gly Asp Val Gln Arg Leu Ala Gln Thr Tyr Gly 
                165                 170                 175     


Thr Leu Ser Gly Leu Val Ala Ser His Glu Asp Pro Asn Arg Met Thr 
            180                 185                 190         


Gly Gly Pro Arg Ala Pro Ala Val Pro Val Gly Phe Gly Val Ile Pro 
        195                 200                 205             


Glu Gly Leu Val Gly Pro Gly Asp Arg Ala Arg Gly Pro Leu Thr Pro 
    210                 215                 220                 


Pro Leu Asp Glu Ile Leu Ser Lys Val Thr Glu Val Ser Asn Thr Leu 
225                 230                 235                 240 


Gln Thr Lys Val Gln Leu Leu Asp Lys Val His Gly Leu Ala Leu Gly 
                245                 250                 255     


His Glu Ala His Leu Gln Arg Leu Arg Glu Ala Pro Pro Ser Pro Leu 
            260                 265                 270         


Thr Ser Leu Ala Leu Leu Glu Glu Tyr Val Asp Arg Arg Leu His Arg 
        275                 280                 285             


Leu Trp Gly Ser Leu Leu Asp Gly Phe Glu Gln Lys Leu Gln Gly Val 
    290                 295                 300                 


Gln Ser Glu Cys Asp Leu Arg Val Gln Glu Val Arg Arg Gln Cys Glu 
305                 310                 315                 320 


Glu Gly Gln Ala Ala Ser Arg Arg Leu His Gln Ser Leu Asp Gly Arg 
                325                 330                 335     


Glu Leu Ala Leu Arg Gln Glu Leu Ser Gln Leu Gly Ser Gln Leu Gln 
            340                 345                 350         


Gly Leu Ser Val Ser Gly Arg Gly Ser Cys Cys Gly Gln Leu Ala Leu 
        355                 360                 365             


Ile Asn Ala Arg Met Asp Gly Leu Glu Arg Ala Leu Gln Ala Val Thr 
    370                 375                 380                 


Glu Thr Gln Arg Gly Pro Gly Ala Pro Ala Gly Asp Glu Leu Thr Arg 
385                 390                 395                 400 


Leu Ser Ala Ala Met Leu Glu Gly Gly Val Asp Gly Leu Leu Glu Gly 
                405                 410                 415     


Leu Glu Thr Leu Asn Gly Thr Glu Gly Gly Ala Arg Gly Cys Cys Leu 
            420                 425                 430         


Arg Leu Asp Met Gly Gly Trp Gly Val Gly Gly Phe Gly Thr Met Leu 
        435                 440                 445             


Glu Glu Arg Val Gln Ser Leu Glu Glu Arg Leu Ala Thr Leu Ala Gly 
    450                 455                 460                 


Glu Leu Ser His Asp Ser Ala Ser Pro Gly Arg Ser Ala Arg Pro Leu 
465                 470                 475                 480 


Val Gln Thr Glu Leu Ala Val Leu Glu Gln Arg Leu Val Ser Leu Glu 
                485                 490                 495     


Thr Ser Cys Thr Pro Ser Thr Thr Ser Ala Ile Leu Asp Asn Leu Val 
            500                 505                 510         


Ala Glu Val Lys Ala Trp Gln Ser Arg Ser Glu Ala Leu Leu Arg Gln 
        515                 520                 525             


Val Ala Ser His Ala Ala Leu Leu Gln Gln Leu Asn Gly Thr Val Ala 
    530                 535                 540                 


Glu Val Gln Gly Gln Leu Ala Glu Gly Thr Gly Ser Ser Leu Gln Gly 
545                 550                 555                 560 


Glu Ile Thr Leu Leu Lys Val Asn Leu Asn Ser Val Ser Lys Ser Leu 
                565                 570                 575     


Thr Gly Leu Ser Asp Ser Val Ser Gln Tyr Ser Asp Ala Phe Leu Ala 
            580                 585                 590         


Ala Asn Thr Ser Leu Asp Glu Arg Glu Arg Lys Val Glu Ala Glu Val 
        595                 600                 605             


Gln Ala Ile Gln Glu Gln Val Ser Ser Gln Gly Ser Arg Leu Gln Ala 
    610                 615                 620                 


Gly His Arg Gln Val Leu Asn Leu Arg Gly Glu Leu Glu Gln Leu Lys 
625                 630                 635                 640 


Ala Gly Val Ala Lys Val Ala Ser Gly Leu Ser Arg Cys Gln Asp Thr 
                645                 650                 655     


Ala Gln Lys Leu Gln His Thr Val Gly His Phe Asp Gln Arg Val Ala 
            660                 665                 670         


Gln Val Glu Gly Ala Cys Arg Arg Leu Gly Leu Leu Ala Ala Gly Leu 
        675                 680                 685             


Asp Ser Leu Pro Thr Glu Pro Leu Arg Pro Arg Glu Gly Leu Trp Ser 
    690                 695                 700                 


His Val Asp Gln Leu Asn Arg Thr Leu Ala Gln His Thr Gln Asp Ile 
705                 710                 715                 720 


Ala Arg Leu Arg Asp Asp Leu Leu Asp Cys Gln Ala Gln Leu Ala Glu 
                725                 730                 735     


Gln Val Arg Pro Gly Gln Ala Asn 
            740                 


<210>  2983
<211>  174
<212>  PRT
<213>  Homo Sapiens

<400>  2983

Gln Asn Asp Thr Glu Pro Ile Val Leu Glu Gly Lys Cys Leu Val Val 
1               5                   10                  15      


Cys Asp Ser Asn Pro Ala Thr Asp Ser Lys Gly Ser Ser Ser Ser Pro 
            20                  25                  30          


Leu Gly Ile Ser Val Arg Ala Ala Asn Ser Lys Val Ala Phe Ser Ala 
        35                  40                  45              


Val Arg Ser Thr Asn His Glu Pro Ser Glu Met Ser Asn Lys Thr Arg 
    50                  55                  60                  


Ile Ile Tyr Phe Asp Gln Ile Leu Val Asn Val Gly Asn Phe Phe Thr 
65                  70                  75                  80  


Leu Glu Ser Val Phe Val Ala Pro Arg Lys Gly Ile Tyr Ser Phe Ser 
                85                  90                  95      


Phe His Val Ile Lys Val Tyr Gln Ser Gln Thr Ile Gln Val Asn Leu 
            100                 105                 110         


Met Leu Asn Gly Lys Pro Val Ile Ser Ala Phe Ala Gly Asp Lys Asp 
        115                 120                 125             


Val Thr Arg Glu Ala Ala Thr Asn Gly Val Leu Leu Tyr Leu Asp Lys 
    130                 135                 140                 


Glu Asp Lys Val Tyr Leu Lys Leu Glu Lys Gly Asn Leu Val Gly Gly 
145                 150                 155                 160 


Trp Gln Tyr Ser Thr Phe Ser Gly Phe Leu Val Phe Pro Leu 
                165                 170                 


<210>  2984
<211>  245
<212>  PRT
<213>  Homo Sapiens

<400>  2984

Trp Leu Thr Thr Gly Ala Pro Glu Pro Pro Pro Leu Ser Gly Ala Pro 
1               5                   10                  15      


Gln Asp Gly Ile Arg Ile Asn Val Thr Thr Leu Lys Asp Asp Gly Asp 
            20                  25                  30          


Ile Ser Lys Gln Gln Val Val Leu Asn Ile Thr Tyr Glu Ser Gly Gln 
        35                  40                  45              


Val Tyr Val Asn Asp Leu Pro Val Asn Ser Gly Val Thr Arg Ile Ser 
    50                  55                  60                  


Cys Gln Thr Leu Ile Val Lys Asn Glu Asn Leu Glu Asn Leu Glu Glu 
65                  70                  75                  80  


Lys Glu Tyr Phe Gly Ile Val Ser Val Arg Ile Leu Val His Glu Trp 
                85                  90                  95      


Pro Met Thr Ser Gly Ser Ser Leu Gln Leu Ile Val Ile Gln Glu Glu 
            100                 105                 110         


Val Val Glu Ile Asp Gly Lys Gln Val Gln Gln Lys Asp Val Thr Glu 
        115                 120                 125             


Ile Asp Ile Leu Val Lys Asn Arg Gly Val Leu Arg His Ser Asn Tyr 
    130                 135                 140                 


Thr Leu Pro Leu Glu Glu Ser Met Leu Tyr Ser Ile Ser Arg Asp Ser 
145                 150                 155                 160 


Asp Ile Leu Phe Thr Leu Pro Asn Leu Ser Lys Lys Glu Ser Val Ser 
                165                 170                 175     


Ser Leu Gln Thr Thr Ser Gln Tyr Leu Ile Arg Asn Val Glu Thr Thr 
            180                 185                 190         


Val Asp Glu Asp Val Leu Pro Gly Lys Leu Pro Glu Thr Pro Leu Arg 
        195                 200                 205             


Ala Glu Pro Pro Ser Ser Tyr Lys Val Met Cys Gln Trp Met Glu Lys 
    210                 215                 220                 


Phe Arg Lys Asp Leu Cys Arg Phe Trp Ser Asn Val Phe Pro Val Phe 
225                 230                 235                 240 


Phe Gln Phe Leu Asn 
                245 


<210>  2985
<211>  57
<212>  PRT
<213>  Homo Sapiens

<400>  2985

Ser Leu Ala Pro Gln Tyr Val Met Tyr Gly Ser Gln Asn Tyr Leu Ile 
1               5                   10                  15      


Glu Thr Asn Ile Thr Ser Asp Asn His Lys Gly Asn Ser Thr Leu Ser 
            20                  25                  30          


Val Pro Lys Arg Cys Asp Ala Asp Ala Pro Glu Asp Gln Cys Thr Val 
        35                  40                  45              


Thr Arg Thr Tyr Leu Phe Leu His Lys 
    50                  55          


<210>  2986
<211>  79
<212>  PRT
<213>  Homo Sapiens

<400>  2986

Val Leu Lys Asp Met Lys Leu Leu Arg Gln Ser Leu Ala Thr Leu Leu 
1               5                   10                  15      


Ile Thr Ser Gln Ile Leu Asn Gln Ile Met Glu Ser Phe Leu Pro Tyr 
            20                  25                  30          


Trp Leu Gln Arg Lys His Gly Val Arg Val Lys Arg Lys Val Gln Ala 
        35                  40                  45              


Leu Lys Ala Asp Ile Asp Ala Thr Leu Tyr Glu Gln Val Ile Leu Glu 
    50                  55                  60                  


Lys Glu Met Gly Thr Tyr Leu Gly Thr Phe Asp Asp Tyr Leu Glu 
65                  70                  75                  


<210>  2987
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  2987

Pro Gly Val Val Pro Lys Asp Ile Glu Asp Ile Tyr Leu Ser Ile Cys 
1               5                   10                  15      


Val Phe Gly Gln Tyr Lys Lys Thr Gln Cys Val Pro Ala Thr Phe Pro 
            20                  25                  30          


Leu Val Phe Asn Ala Arg Met Val Phe Glu Lys Val Phe Pro Asp Ala 
        35                  40                  45              


Val Asp Pro Gly Asp Val Val Thr Gln Leu Glu Tyr Asp Thr Ala Val 
    50                  55                  60                  


Phe Glu Leu Ile Gln Leu Val Pro Pro Val Gly Glu Thr Leu Ser Thr 
65                  70                  75                  80  


Tyr Asp Glu Asn Thr Arg Asp Phe Met Phe Pro Gly Pro Asn Gln Met 
                85                  90                  95      


Ser Gly His His Asp Ser Asn Arg Gln Val Thr Met Arg Arg Ile Ser 
            100                 105                 110         


Gly Leu Arg Gly Asn Ala Pro Arg Leu Glu Phe Ser Thr Thr Ser Val 
        115                 120                 125             


Ile Thr Glu Cys Leu Ile Ser Ser Arg Lys Cys His Thr Gln Asp Lys 
    130                 135                 140                 


Phe Ile Tyr His Leu Ala Pro Val Glu Lys Ser His Gly Arg Leu Gln 
145                 150                 155                 160 


Asn Arg Thr Ser Arg Ser Gln Lys Lys Lys Ser Lys Ser Pro Glu Arg 
                165                 170                 175     


Ser Lys Tyr Cys Ile Asn Ala Lys Asn Tyr Glu Gln Pro Thr Ile Ser 
            180                 185                 190         


Ser Lys Ser His Ser Pro Ser Pro Tyr Thr Lys Arg Arg Met Cys Glu 
        195                 200                 205             


Leu Ser Glu Asp Thr Arg Arg Arg Leu Ala His Leu Asn Leu Gly Pro 
    210                 215                 220                 


Tyr Glu Phe Lys Lys Glu Thr Asp Lys Pro Pro Phe Val Ile Arg His 
225                 230                 235                 240 


Val Asp Pro Pro Ser Pro Arg Ala Asp Thr Leu Leu Gly Ser Ser Gly 
                245                 250                 255     


Arg Asp Cys Glu Arg Asp Gly Trp Ser Arg Val His Asn Asp His Ser 
            260                 265                 270         


His Leu Gly Cys Cys Arg Pro Lys Asp Tyr Lys Val Ile Arg Thr Pro 
        275                 280                 285             


His Gly Arg Asp Phe Asp Asp Ser Leu Glu Lys Cys Glu Glu Tyr Leu 
    290                 295                 300                 


Ser Pro Arg Ser Cys Ser Lys Pro Arg His Ser Ala Arg Thr Leu Leu 
305                 310                 315                 320 


Val His Ser Ala Pro Ser Thr Met Pro Lys His Ser Pro Ser Pro Val 
                325                 330                 335     


Leu Asn Arg Ala Ser Leu Arg Glu Arg Phe His Ser Asp Trp Cys Ser 
            340                 345                 350         


Pro Ser Asn Cys Asp Glu Ile His Asp Arg Asp Glu Arg Asp Leu Glu 
        355                 360                 365             


Lys Asp Asp Glu Leu Glu Leu Lys Arg Ser Leu Leu Cys Arg Asp Ser 
    370                 375                 380                 


Ala Tyr Asp Ser Asp Pro Glu Tyr Ser Ser Cys Gln Gln Pro Arg Gly 
385                 390                 395                 400 


Thr Phe His Leu Asp Asp Gly Glu Tyr Trp Ser Asn Arg Ala Ala Ser 
                405                 410                 415     


Tyr Lys Gly Lys Ser His Arg Pro Ile Phe Glu Asn Ser Met Asp Lys 
            420                 425                 430         


Met Tyr Arg Asn Leu Tyr Lys Lys Ala Cys Ser Ser Ala Ser His Thr 
        435                 440                 445             


Gln Glu Ser Phe 
    450         


<210>  2988
<211>  192
<212>  PRT
<213>  Homo Sapiens

<400>  2988

Ala Leu Ile Pro Glu Pro Glu Val Lys Ile Glu Val Leu Gln Lys Pro 
1               5                   10                  15      


Phe Ile Cys His Arg Lys Thr Lys Gly Gly Asp Leu Met Leu Val His 
            20                  25                  30          


Tyr Glu Gly Tyr Leu Glu Lys Asp Gly Ser Leu Phe His Ser Thr His 
        35                  40                  45              


Lys His Asn Asn Gly Gln Pro Ile Trp Phe Thr Leu Gly Ile Leu Glu 
    50                  55                  60                  


Ala Leu Lys Gly Trp Asp Gln Gly Leu Lys Gly Met Cys Val Gly Glu 
65                  70                  75                  80  


Lys Arg Lys Leu Ile Ile Pro Pro Ala Leu Gly Tyr Gly Lys Glu Gly 
                85                  90                  95      


Lys Gly Lys Ile Pro Pro Glu Ser Thr Leu Ile Phe Asn Ile Asp Leu 
            100                 105                 110         


Leu Glu Ile Arg Asn Gly Pro Arg Ser His Glu Ser Phe Gln Glu Met 
        115                 120                 125             


Asp Leu Asn Asp Asp Trp Lys Leu Ser Lys Asp Glu Val Lys Ala Tyr 
    130                 135                 140                 


Leu Lys Lys Glu Phe Glu Lys His Gly Ala Val Val Asn Glu Ser His 
145                 150                 155                 160 


His Asp Ala Leu Val Glu Asp Ile Phe Asp Lys Glu Asp Glu Asp Lys 
                165                 170                 175     


Asp Gly Phe Ile Ser Ala Arg Glu Phe Thr Tyr Lys His Asp Glu Leu 
            180                 185                 190         


<210>  2989
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  2989

Arg Trp Leu Leu Cys Asn Gly Ser Leu Phe Arg Tyr Lys His Pro Ser 
1               5                   10                  15      


Glu Glu Glu Leu Arg Ala Leu Ala Gly Lys Pro Arg Pro Arg Gly Arg 
            20                  25                  30          


Lys Glu Arg Trp Ala Asn Gly Leu Ser Glu Glu Lys Pro Leu Ser Val 
        35                  40                  45              


Pro Arg Asp Ala Pro Phe Gln Leu Glu Thr Cys Pro Leu Thr Thr Val 
    50                  55                  60                  


Asp Ala Leu Val Leu Arg 
65                  70  


<210>  2990
<211>  369
<212>  PRT
<213>  Homo Sapiens

<400>  2990

Lys Asp Glu Gly Phe Ala Val Lys Ala Leu Trp Gly Arg Thr Gln Glu 
1               5                   10                  15      


Glu Ala Glu Glu Leu Ala Lys Glu Met Ser Val Pro Phe Tyr Thr Ser 
            20                  25                  30          


Arg Ile Asp Glu Val Leu Leu His Gln Asp Val Asp Leu Val Cys Ile 
        35                  40                  45              


Asn Leu Pro Pro Pro Leu Thr Arg Gln Ile Ala Val Lys Thr Leu Gly 
    50                  55                  60                  


Ile Gly Lys Asn Val Ile Cys Asp Arg Thr Ala Thr Pro Leu Asp Ala 
65                  70                  75                  80  


Phe Arg Met Thr Ser Ala Ala His Tyr Tyr Pro Lys Leu Met Ser Ile 
                85                  90                  95      


Met Gly Asn Val Leu Arg Phe Leu Pro Ala Phe Val Arg Met Lys Gln 
            100                 105                 110         


Leu Ile Glu Glu Gly Tyr Val Gly Glu Pro Leu Val Cys Glu Val Gln 
        115                 120                 125             


Val His Gly Gly Ser Leu Leu Gly Lys Lys Tyr Asn Trp Ser Cys Asp 
    130                 135                 140                 


Asp Leu Met Gly Gly Gly Gly Leu His Ser Val Gly Thr Tyr Ile Ile 
145                 150                 155                 160 


Asp Leu Leu Thr Phe Leu Thr Gly Gln Lys Ala Val Lys Val His Gly 
                165                 170                 175     


Leu Leu Lys Thr Phe Val Lys Gln Thr Asp His Ile Lys Gly Ile Arg 
            180                 185                 190         


Gln Ile Thr Ser Asp Asp Phe Cys Thr Phe Gln Met Val Leu Glu Gly 
        195                 200                 205             


Gly Val Cys Cys Thr Val Thr Leu Asn Phe Asn Val Pro Gly Glu Phe 
    210                 215                 220                 


Lys Gln Asp Val Thr Val Val Gly Ser Ala Gly Arg Leu Leu Ala Val 
225                 230                 235                 240 


Gly Thr Asp Leu Tyr Gly Gln Arg Asn Ser Ala Pro Glu Gln Glu Leu 
                245                 250                 255     


Leu Val Gln Asp Ala Thr Pro Val Ser Asn Ser Leu Leu Pro Glu Lys 
            260                 265                 270         


Ala Phe Ser Asp Ile Pro Ser Pro Tyr Leu Arg Gly Thr Ile Lys Met 
        275                 280                 285             


Met Gln Ala Val Arg Gln Ala Phe Gln Asp Gln Asp Asp Arg Arg Thr 
    290                 295                 300                 


Trp Asp Gly Arg Pro Leu Thr Met Ala Ala Thr Phe Asp Asp Cys Leu 
305                 310                 315                 320 


Tyr Ala Leu Cys Val Val Asp Thr Ile Lys Arg Ser Ser Gln Thr Gly 
                325                 330                 335     


Glu Trp Gln Asn Ile Ala Ile Met Thr Glu Glu Pro Glu Leu Ser Pro 
            340                 345                 350         


Ala Tyr Leu Ile Ser Glu Ala Met Arg Arg Ser Arg Met Ser Leu Tyr 
        355                 360                 365             


Cys 
    


<210>  2991
<211>  377
<212>  PRT
<213>  Homo Sapiens

<400>  2991

Arg Leu Leu Asn Tyr Phe Thr Trp Pro Thr Thr Thr Ser Ile Glu Val 
1               5                   10                  15      


Gln Tyr Val Glu Lys Met Glu Phe Pro Ala Val Thr Phe Cys Asn Leu 
            20                  25                  30          


Asn Arg Phe Gln Thr Asp Ala Val Ala Lys Phe Gly Val Ile Phe Phe 
        35                  40                  45              


Leu Trp His Ile Val Ser Lys Val Leu His Leu Gln Glu Ile Thr Ala 
    50                  55                  60                  


Asn Ser Thr Gly Ser Arg Glu Ala Thr Asp Phe Ala Ala Ser His Gln 
65                  70                  75                  80  


Asn Phe Ser Ile Val Glu Phe Ile Arg Asn Lys Gly Phe Tyr Leu Asn 
                85                  90                  95      


Asn Ser Thr Leu Leu Asp Cys Glu Phe Phe Gly Lys Pro Cys Ser Pro 
            100                 105                 110         


Lys Asp Phe Ala His Val Phe Thr Glu Tyr Gly Asn Cys Phe Thr Phe 
        115                 120                 125             


Asn His Gly Glu Thr Leu Gln Ala Lys Arg Lys Val Ser Val Ser Gly 
    130                 135                 140                 


Arg Gly Leu Ser Leu Leu Phe Asn Val Asn Gln Glu Ala Phe Thr Asp 
145                 150                 155                 160 


Asn Pro Ala Leu Gly Phe Val Asp Ala Gly Ile Ile Phe Val Ile His 
                165                 170                 175     


Ser Pro Lys Lys Val Pro Gln Phe Asp Gly Leu Gly Leu Leu Ser Pro 
            180                 185                 190         


Val Gly Met His Ala Arg Val Thr Ile Arg Gln Val Lys Thr Val His 
        195                 200                 205             


Gln Glu Tyr Pro Trp Gly Glu Cys Asn Pro Asn Ile Lys Leu Gln Asn 
    210                 215                 220                 


Phe Ser Ser Tyr Ser Thr Ser Gly Cys Leu Lys Glu Cys Lys Ala Gln 
225                 230                 235                 240 


His Ile Lys Lys Gln Cys Gly Cys Val Pro Phe Leu Leu Pro Gly Tyr 
                245                 250                 255     


Gly Ile Glu Cys Asp Leu Gln Lys Tyr Phe Ser Cys Val Ser Pro Val 
            260                 265                 270         


Leu Asp His Ile Glu Phe Lys Asp Leu Cys Thr Val Gly Thr His Asn 
        275                 280                 285             


Ser Ser Cys Pro Val Ser Cys Glu Glu Ile Glu Tyr Pro Ala Thr Ile 
    290                 295                 300                 


Ser Tyr Ser Ser Phe Pro Ser Gln Lys Ala Leu Lys Tyr Leu Ser Lys 
305                 310                 315                 320 


Lys Leu Asn Gln Ser Arg Lys Tyr Ile Arg Glu Asn Leu Val Lys Ile 
                325                 330                 335     


Glu Ile Asn Tyr Ser Asp Leu Asn Tyr Lys Ile Thr Gln Gln Gln Lys 
            340                 345                 350         


Ala Val Ser Val Ser Glu Leu Leu Ala Asp Leu Gly Gly Gln Leu Gly 
        355                 360                 365             


Leu Phe Cys Gly Ala Ser Leu Ile Thr 
    370                 375         


<210>  2992
<211>  89
<212>  PRT
<213>  Homo Sapiens

<400>  2992

Ser Arg Ile Leu Tyr Thr Asp Met Val Ala Cys Val Val Pro Ser Glu 
1               5                   10                  15      


Cys Val Lys His Cys Gly Val Asp Val Gly Cys Thr Asn Tyr Ala Tyr 
            20                  25                  30          


Pro Thr Met Val Leu Glu Leu Met Pro Gln Gly Leu Arg Gly Leu Met 
        35                  40                  45              


Leu Ser Val Met Leu Ala Ser Leu Met Ser Ser Leu Thr Ser Ile Phe 
    50                  55                  60                  


Asn Ser Ala Ser Thr Leu Phe Thr Ile Asp Leu Tyr Thr Lys Met Arg 
65                  70                  75                  80  


Lys Gln Ala Ser Glu Lys Glu Leu Leu 
                85                  


<210>  2993
<211>  128
<212>  PRT
<213>  Homo Sapiens

<400>  2993

Gly Leu Glu Thr Glu Ser Pro Val Arg Thr Leu Gln Val Glu Thr Leu 
1               5                   10                  15      


Val Glu Pro Pro Glu Pro Cys Ala Glu Pro Ala Ala Phe Gly Asp Thr 
            20                  25                  30          


Leu His Ile His Tyr Thr Gly Ser Leu Val Asp Gly Arg Ile Ile Asp 
        35                  40                  45              


Thr Ser Leu Thr Arg Asp Pro Leu Val Ile Glu Leu Gly Gln Lys Gln 
    50                  55                  60                  


Val Ile Pro Gly Leu Glu Gln Ser Leu Leu Asp Met Cys Val Gly Glu 
65                  70                  75                  80  


Lys Arg Arg Ala Ile Ile Pro Ser His Leu Ala Tyr Gly Lys Arg Gly 
                85                  90                  95      


Phe Pro Pro Ser Val Pro Ala Asp Ala Val Val Gln Tyr Asp Val Glu 
            100                 105                 110         


Leu Ile Ala Leu Ile Arg Ala Asn Tyr Trp Leu Lys Leu Val Lys Gly 
        115                 120                 125             


<210>  2994
<211>  490
<212>  PRT
<213>  Homo Sapiens

<400>  2994

Gly Ser Pro Ala Leu Arg Trp Tyr Arg Thr Ser Cys His Leu Thr Lys 
1               5                   10                  15      


Ala Val Pro Gly Asn Pro Leu Gly Tyr Leu Ser Phe Leu Ala Lys Asp 
            20                  25                  30          


Ala Gln Gly Leu Ala Leu Ile His Ala Arg Trp Asp Ala His Arg Arg 
        35                  40                  45              


Leu Gln Ala Cys Ser Trp Glu Asp Glu Pro Glu Leu Thr Ala Ala Tyr 
    50                  55                  60                  


Gly Ala Leu Cys Ala His Glu Thr Ala Trp Gly Ser Phe Ile His Thr 
65                  70                  75                  80  


Pro Gly Pro Glu Leu Gln Arg Ala Leu Ala Thr Leu Gln Ser Gln Trp 
                85                  90                  95      


Glu Ala Cys Arg Ala Leu Glu Glu Ser Pro Ala Gly Ala Arg Lys Lys 
            100                 105                 110         


Arg Ala Ala Gly Gln Ser Gly Val Pro Gly Gly Gly His Gln Arg Glu 
        115                 120                 125             


Lys Arg Gly Trp Thr Met Pro Gly Thr Leu Trp Cys Gly Val Gly Asp 
    130                 135                 140                 


Ser Ala Gly Asn Ser Ser Glu Leu Gly Val Phe Gln Gly Pro Asp Leu 
145                 150                 155                 160 


Cys Cys Arg Glu His Asp Arg Cys Pro Gln Asn Ile Ser Pro Leu Gln 
                165                 170                 175     


Tyr Asn Tyr Gly Ile Arg Asn Tyr Arg Phe His Thr Ile Ser His Cys 
            180                 185                 190         


Asp Cys Asp Thr Arg Phe Gln Gln Cys Leu Gln Asn Gln His Asp Ser 
        195                 200                 205             


Ile Ser Asp Ile Val Gly Val Ala Phe Phe Asn Val Leu Glu Ile Pro 
    210                 215                 220                 


Cys Phe Val Leu Glu Glu Gln Glu Ala Cys Val Ala Trp Tyr Trp Trp 
225                 230                 235                 240 


Gly Gly Cys Arg Met Tyr Gly Thr Val Pro Leu Ala Arg Leu Gln Pro 
                245                 250                 255     


Arg Thr Phe Tyr Asn Ala Ser Trp Ser Ser Arg Ala Thr Ser Pro Thr 
            260                 265                 270         


Pro Ser Ser Arg Ser Pro Ala Pro Pro Lys Pro Arg Gln Lys Gln His 
        275                 280                 285             


Leu Arg Lys Gly Pro Pro His Gln Lys Gly Ser Lys Arg Pro Ser Lys 
    290                 295                 300                 


Ala Asn Thr Thr Ala Leu Gln Asp Pro Met Val Ser Pro Arg Leu Asp 
305                 310                 315                 320 


Val Ala Pro Thr Gly Leu Gln Gly Pro Gln Gly Gly Leu Lys Pro Gln 
                325                 330                 335     


Gly Ala Arg Trp Val Cys Arg Ser Phe Arg Arg His Leu Asp Gln Cys 
            340                 345                 350         


Glu His Gln Ile Gly Pro Arg Glu Ile Glu Phe Gln Leu Leu Asn Ser 
        355                 360                 365             


Ala Gln Glu Pro Leu Phe His Cys Asn Cys Thr Arg Arg Leu Ala Arg 
    370                 375                 380                 


Phe Leu Arg Leu His Ser Pro Pro Glu Val Thr Asn Met Leu Trp Glu 
385                 390                 395                 400 


Leu Leu Gly Thr Thr Cys Phe Lys Leu Ala Pro Pro Leu Asp Cys Val 
                405                 410                 415     


Glu Gly Lys Asn Cys Ser Arg Asp Pro Arg Ala Ile Arg Val Ser Ala 
            420                 425                 430         


Arg His Leu Arg Arg Leu Gln Gln Arg Arg His Gln Leu Gln Asp Lys 
        435                 440                 445             


Gly Thr Asp Glu Arg Gln Pro Trp Pro Ser Glu Pro Leu Arg Gly Pro 
    450                 455                 460                 


Met Ser Phe Tyr Asn Gln Cys Leu Gln Leu Thr Gln Ala Ala Arg Arg 
465                 470                 475                 480 


Pro Asp Arg Gln Gln Lys Ser Trp Ser Gln 
                485                 490 


<210>  2995
<211>  468
<212>  PRT
<213>  Homo Sapiens

<400>  2995

Gly Ser Asp Glu Pro Gly Pro Glu Gly Leu Thr Ser Thr Ser Leu Leu 
1               5                   10                  15      


Asp Leu Leu Leu Pro Thr Gly Leu Glu Pro Leu Asp Ser Glu Glu Pro 
            20                  25                  30          


Ser Glu Thr Met Gly Leu Gly Ala Gly Leu Gly Ala Pro Gly Ser Gly 
        35                  40                  45              


Phe Pro Ser Glu Glu Asn Glu Glu Ser Arg Ile Leu Gln Pro Pro Gln 
    50                  55                  60                  


Tyr Phe Trp Glu Glu Glu Glu Glu Leu Asn Asp Ser Ser Leu Asp Leu 
65                  70                  75                  80  


Gly Pro Thr Ala Asp Tyr Val Phe Pro Asp Leu Thr Glu Lys Ala Gly 
                85                  90                  95      


Ser Ile Glu Asp Thr Ser Gln Ala Gln Glu Leu Pro Asn Leu Pro Ser 
            100                 105                 110         


Pro Leu Pro Lys Met Asn Leu Val Glu Pro Pro Trp His Met Pro Pro 
        115                 120                 125             


Arg Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Glu Arg Glu Lys Glu 
    130                 135                 140                 


Glu Val Glu Lys Gln Glu Glu Glu Glu Glu Glu Glu Leu Leu Pro Val 
145                 150                 155                 160 


Asn Gly Ser Gln Glu Glu Ala Lys Pro Gln Val Arg Asp Phe Ser Leu 
                165                 170                 175     


Thr Ser Ser Ser Gln Thr Pro Gly Ala Thr Lys Ser Arg His Glu Asp 
            180                 185                 190         


Ser Gly Asp Gln Ala Ser Ser Gly Val Glu Val Glu Ser Ser Met Gly 
        195                 200                 205             


Pro Ser Leu Leu Leu Pro Ser Val Thr Pro Thr Thr Val Thr Pro Gly 
    210                 215                 220                 


Asp Gln Asp Ser Thr Ser Gln Glu Ala Glu Ala Thr Val Leu Pro Ala 
225                 230                 235                 240 


Ala Gly Leu Gly Val Glu Phe Glu Ala Pro Gln Glu Ala Ser Glu Glu 
                245                 250                 255     


Ala Thr Ala Gly Ala Ala Gly Leu Ser Gly Gln His Glu Glu Val Pro 
            260                 265                 270         


Ala Leu Pro Ser Phe Pro Gln Thr Thr Ala Pro Ser Gly Ala Glu His 
        275                 280                 285             


Pro Asp Glu Asp Pro Leu Gly Ser Arg Thr Ser Ala Ser Ser Pro Leu 
    290                 295                 300                 


Ala Pro Gly Asp Met Glu Leu Thr Pro Ser Ser Ala Thr Leu Gly Gln 
305                 310                 315                 320 


Glu Asp Leu Asn Gln Gln Leu Leu Glu Gly Gln Ala Ala Glu Ala Gln 
                325                 330                 335     


Ser Arg Ile Pro Trp Asp Ser Thr Gln Val Ile Cys Lys Asp Trp Ser 
            340                 345                 350         


Asn Leu Ala Gly Lys Asn Tyr Ile Ile Leu Asn Met Thr Glu Asn Ile 
        355                 360                 365             


Asp Cys Glu Val Phe Arg Gln His Arg Gly Pro Gln Leu Leu Ala Leu 
    370                 375                 380                 


Val Glu Glu Val Leu Pro Arg His Gly Ser Gly His His Gly Ala Trp 
385                 390                 395                 400 


His Ile Ser Leu Ser Lys Pro Ser Glu Lys Glu Gln His Leu Leu Met 
                405                 410                 415     


Thr Leu Val Gly Glu Gln Gly Val Val Pro Thr Gln Asp Val Leu Ser 
            420                 425                 430         


Met Leu Gly Asp Ile Arg Arg Ser Leu Glu Glu Ile Gly Ile Gln Asn 
        435                 440                 445             


Tyr Ser Thr Thr Ser Ser Cys Gln Ala Arg Ala Ser Gln Val Arg Ser 
    450                 455                 460                 


Asp Tyr Gly Thr 
465             


<210>  2996
<211>  652
<212>  PRT
<213>  Homo Sapiens

<400>  2996

Gln Ala Pro Ala Pro Thr Val Asn Thr His Phe Gly Lys Leu Arg Gly 
1               5                   10                  15      


Ala Arg Val Pro Leu Pro Ser Glu Ile Leu Gly Pro Val Asp Gln Tyr 
            20                  25                  30          


Leu Gly Val Pro Tyr Ala Ala Pro Pro Ile Gly Glu Lys Arg Phe Leu 
        35                  40                  45              


Pro Pro Glu Pro Pro Pro Tyr Trp Ser Gly Ile Arg Asn Ala Thr His 
    50                  55                  60                  


Phe Pro Pro Val Cys Pro Gln Asn Ile His Thr Ala Val Pro Glu Val 
65                  70                  75                  80  


Met Leu Pro Val Trp Phe Thr Ala Asn Leu Asp Ile Val Ala Thr Tyr 
                85                  90                  95      


Ile Gln Glu Pro Asn Glu Asp Cys Leu Tyr Leu Asn Val Tyr Val Pro 
            100                 105                 110         


Thr Glu Asp Gly Ser Gly Ala Lys Lys Gln Gly Glu Asp Leu Ala Asp 
        115                 120                 125             


Asn Asp Gly Asp Glu Asp Glu Asp Ile Arg Asp Ser Gly Ala Lys Pro 
    130                 135                 140                 


Val Met Val Tyr Ile His Gly Gly Ser Tyr Met Glu Gly Thr Gly Asn 
145                 150                 155                 160 


Met Ile Asp Gly Ser Ile Leu Ala Ser Tyr Gly Asn Val Ile Val Ile 
                165                 170                 175     


Thr Leu Asn Tyr Arg Val Gly Val Leu Gly Phe Leu Ser Thr Gly Asp 
            180                 185                 190         


Gln Ala Ala Lys Gly Asn Tyr Gly Leu Leu Asp Gln Ile Gln Ala Leu 
        195                 200                 205             


Arg Trp Val Ser Glu Asn Ile Ala Phe Phe Gly Gly Asp Pro Arg Arg 
    210                 215                 220                 


Ile Thr Val Phe Gly Ser Gly Ile Gly Ala Ser Cys Val Ser Leu Leu 
225                 230                 235                 240 


Thr Leu Ser His His Ser Glu Gly Leu Phe Gln Arg Ala Ile Ile Gln 
                245                 250                 255     


Ser Gly Ser Ala Leu Ser Ser Trp Ala Val Asn Tyr Gln Pro Val Lys 
            260                 265                 270         


Tyr Thr Ser Leu Leu Ala Asp Lys Val Gly Cys Asn Val Leu Asp Thr 
        275                 280                 285             


Val Asp Met Val Asp Cys Leu Arg Gln Lys Ser Ala Lys Glu Leu Val 
    290                 295                 300                 


Glu Gln Asp Ile Gln Pro Ala Arg Tyr His Val Ala Phe Gly Pro Val 
305                 310                 315                 320 


Ile Asp Gly Asp Val Ile Pro Asp Asp Pro Glu Ile Leu Met Glu Gln 
                325                 330                 335     


Gly Glu Phe Leu Asn Tyr Asp Ile Met Leu Gly Val Asn Gln Gly Glu 
            340                 345                 350         


Gly Leu Lys Phe Val Glu Gly Val Val Asp Pro Glu Asp Gly Val Ser 
        355                 360                 365             


Gly Thr Asp Phe Asp Tyr Ser Val Ser Asn Phe Val Asp Asn Leu Tyr 
    370                 375                 380                 


Gly Tyr Pro Glu Gly Lys Asp Thr Leu Arg Glu Thr Ile Lys Phe Met 
385                 390                 395                 400 


Tyr Thr Asp Trp Ala Asp Arg Asp Asn Pro Glu Thr Arg Arg Lys Thr 
                405                 410                 415     


Leu Val Ala Leu Phe Thr Asp His Gln Trp Val Glu Pro Ser Val Val 
            420                 425                 430         


Thr Ala Asp Leu His Ala Arg Tyr Gly Ser Pro Thr Tyr Phe Tyr Ala 
        435                 440                 445             


Phe Tyr His His Cys Gln Ser Leu Met Lys Pro Ala Trp Ser Asp Ala 
    450                 455                 460                 


Ala His Gly Asp Glu Val Pro Tyr Val Phe Gly Val Pro Met Val Gly 
465                 470                 475                 480 


Pro Thr Asp Leu Phe Pro Cys Asn Phe Ser Lys Asn Asp Val Met Leu 
                485                 490                 495     


Ser Ala Val Val Met Thr Tyr Trp Thr Asn Phe Ala Lys Thr Gly Asp 
            500                 505                 510         


Pro Asn Lys Pro Val Pro Gln Asp Thr Lys Phe Ile His Thr Lys Ala 
        515                 520                 525             


Asn Arg Phe Glu Glu Val Ala Trp Ser Lys Tyr Asn Pro Arg Asp Gln 
    530                 535                 540                 


Leu Tyr Leu His Ile Gly Leu Lys Pro Arg Val Arg Asp His Tyr Arg 
545                 550                 555                 560 


Ala Thr Lys Val Ala Phe Trp Lys His Leu Val Pro His Leu Tyr Asn 
                565                 570                 575     


Leu His Asp Met Phe His Tyr Thr Ser Thr Thr Thr Lys Val Pro Pro 
            580                 585                 590         


Pro Asp Thr Thr His Ser Ser His Ile Thr Arg Arg Pro Asn Gly Lys 
        595                 600                 605             


Thr Trp Ser Thr Lys Arg Pro Ala Ile Ser Pro Ala Tyr Ser Asn Glu 
    610                 615                 620                 


Asn Ala Gln Gly Ser Trp Asn Gly Asp Gln Asp Ala Gly Pro Leu Leu 
625                 630                 635                 640 


Val Glu Asn Pro Arg Asp Tyr Ser Thr Glu Leu Ser 
                645                 650         


<210>  2997
<211>  65
<212>  PRT
<213>  Homo Sapiens

<400>  2997

Met Glu Ser Ala Arg Glu Asn Ile Asp Leu Gln Pro Gly Ser Ser Asp 
1               5                   10                  15      


Pro Arg Ser Gln Pro Ile Asn Leu Asn His Tyr Ala Thr Lys Lys Ser 
            20                  25                  30          


Val Ala Glu Ser Met Leu Asp Val Ala Leu Phe Met Ser Asn Ala Met 
        35                  40                  45              


Arg Leu Lys Ala Val Leu Glu Gln Gly Pro Ser Ser His Tyr Tyr Thr 
    50                  55                  60                  


Thr 
65  


<210>  2998
<211>  482
<212>  PRT
<213>  Homo Sapiens

<400>  2998

Ile Asp Glu Thr Arg Ala His Leu Leu Leu Lys Glu Lys Met Met Arg 
1               5                   10                  15      


Leu Gly Gly Arg Leu Val Leu Asn Thr Lys Glu Glu Leu Ala Asn Glu 
            20                  25                  30          


Arg Leu Met Thr Leu Lys Ile Ala Glu Met Lys Glu Ala Met Arg Thr 
        35                  40                  45              


Leu Ile Phe Pro Pro Ser Met His Phe Phe Gln Ala Lys His Leu Ile 
    50                  55                  60                  


Glu Arg Ser Gln Val Phe Asn Ile Leu Arg Met Met Pro Lys Gly Ala 
65                  70                  75                  80  


Ala Leu His Leu His Asp Ile Gly Ile Val Thr Met Asp Trp Leu Val 
                85                  90                  95      


Arg Asn Val Thr Tyr Arg Pro His Cys His Ile Cys Phe Thr Pro Arg 
            100                 105                 110         


Gly Ile Met Gln Phe Arg Phe Ala His Pro Thr Pro Arg Pro Ser Glu 
        115                 120                 125             


Lys Cys Ser Lys Trp Ile Leu Leu Glu Asp Tyr Arg Lys Arg Val Gln 
    130                 135                 140                 


Asn Val Thr Glu Phe Asp Asp Ser Leu Leu Arg Asn Phe Thr Leu Val 
145                 150                 155                 160 


Thr Gln His Pro Glu Val Ile Tyr Thr Asn Gln Asn Val Val Trp Ser 
                165                 170                 175     


Lys Phe Glu Thr Ile Phe Phe Thr Ile Ser Gly Leu Ile His Tyr Ala 
            180                 185                 190         


Pro Val Phe Arg Asp Tyr Val Phe Arg Ser Met Gln Glu Phe Tyr Glu 
        195                 200                 205             


Asp Asn Val Leu Tyr Met Glu Ile Arg Ala Arg Leu Leu Pro Val Tyr 
    210                 215                 220                 


Glu Leu Ser Gly Glu His His Asp Glu Glu Trp Ser Val Lys Thr Tyr 
225                 230                 235                 240 


Gln Glu Val Ala Gln Lys Phe Val Glu Thr His Pro Glu Phe Ile Gly 
                245                 250                 255     


Ile Lys Ile Ile Tyr Ser Asp His Arg Ser Lys Asp Val Ala Val Ile 
            260                 265                 270         


Ala Glu Ser Ile Arg Met Ala Met Gly Leu Arg Ile Lys Phe Pro Thr 
        275                 280                 285             


Val Val Ala Gly Phe Asp Leu Val Gly His Glu Asp Thr Gly His Ser 
    290                 295                 300                 


Leu His Asp Tyr Lys Glu Ala Leu Met Ile Pro Ala Lys Asp Gly Val 
305                 310                 315                 320 


Lys Leu Pro Tyr Phe Phe His Ala Gly Glu Thr Asp Trp Gln Gly Thr 
                325                 330                 335     


Ser Ile Asp Arg Asn Ile Leu Asp Ala Leu Met Leu Asn Thr Thr Arg 
            340                 345                 350         


Ile Gly His Gly Phe Ala Leu Ser Lys His Pro Ala Val Arg Thr Tyr 
        355                 360                 365             


Ser Trp Lys Lys Asp Ile Pro Ile Glu Val Cys Pro Ile Ser Asn Gln 
    370                 375                 380                 


Val Leu Lys Leu Val Ser Asp Leu Arg Asn His Pro Val Ala Thr Leu 
385                 390                 395                 400 


Met Ala Thr Gly His Pro Met Val Ile Ser Ser Asp Asp Pro Ala Met 
                405                 410                 415     


Phe Gly Ala Lys Gly Leu Ser Tyr Asp Phe Tyr Glu Val Phe Met Gly 
            420                 425                 430         


Ile Gly Gly Met Lys Ala Asp Leu Arg Thr Leu Lys Gln Leu Ala Met 
        435                 440                 445             


Asn Ser Ile Lys Tyr Ser Thr Leu Leu Glu Ser Glu Lys Asn Thr Phe 
    450                 455                 460                 


Met Glu Ile Trp Lys Lys Arg Trp Asp Lys Phe Ile Ala Asp Val Ala 
465                 470                 475                 480 


Thr Lys 
        


<210>  2999
<211>  123
<212>  PRT
<213>  Homo Sapiens

<400>  2999

Asn Leu Val Gln Phe Gly Val Met Ile Glu Lys Met Thr Gly Lys Ser 
1               5                   10                  15      


Ala Leu Gln Tyr Asn Asp Tyr Gly Cys Tyr Cys Gly Ile Gly Gly Ser 
            20                  25                  30          


His Trp Pro Val Asp Gln Thr Asp Trp Cys Cys His Ala His Asp Cys 
        35                  40                  45              


Cys Tyr Gly Arg Leu Glu Lys Leu Gly Cys Glu Pro Lys Leu Glu Lys 
    50                  55                  60                  


Tyr Leu Phe Ser Val Ser Glu Arg Gly Ile Phe Cys Ala Gly Arg Thr 
65                  70                  75                  80  


Thr Cys Gln Arg Leu Thr Cys Glu Cys Asp Lys Arg Ala Ala Leu Cys 
                85                  90                  95      


Phe Arg Arg Asn Leu Gly Thr Tyr Asn Arg Lys Tyr Ala His Tyr Pro 
            100                 105                 110         


Asn Lys Leu Cys Thr Gly Pro Thr Pro Pro Cys 
        115                 120             


<210>  3000
<211>  452
<212>  PRT
<213>  Homo Sapiens

<400>  3000

Cys Pro Thr Arg Gly Ser Val Leu Leu Ala Gln Glu Leu Pro Gln Gln 
1               5                   10                  15      


Leu Thr Ser Pro Gly Tyr Pro Glu Pro Tyr Gly Lys Gly Gln Glu Ser 
            20                  25                  30          


Ser Thr Asp Ile Lys Ala Pro Glu Gly Phe Ala Val Arg Leu Val Phe 
        35                  40                  45              


Gln Asp Phe Asp Leu Glu Pro Ser Gln Asp Cys Ala Gly Asp Ser Val 
    50                  55                  60                  


Thr Ile Ser Phe Val Gly Ser Asp Pro Ser Gln Phe Cys Gly Gln Gln 
65                  70                  75                  80  


Gly Ser Pro Leu Gly Arg Pro Pro Gly Gln Arg Glu Phe Val Ser Ser 
                85                  90                  95      


Gly Arg Ser Leu Arg Leu Thr Phe Arg Thr Gln Pro Ser Ser Glu Asn 
            100                 105                 110         


Lys Thr Ala His Leu His Lys Gly Phe Leu Ala Leu Tyr Gln Thr Val 
        115                 120                 125             


Ala Val Asn Tyr Ser Gln Pro Ile Ser Glu Ala Ser Arg Gly Ser Glu 
    130                 135                 140                 


Ala Ile Asn Ala Pro Gly Asp Asn Pro Ala Lys Val Gln Asn His Cys 
145                 150                 155                 160 


Gln Glu Pro Tyr Tyr Gln Ala Ala Ala Ala Gly Ala Leu Thr Cys Ala 
                165                 170                 175     


Thr Pro Gly Thr Trp Lys Asp Arg Gln Asp Gly Glu Glu Val Leu Gln 
            180                 185                 190         


Cys Met Pro Val Cys Gly Arg Pro Val Thr Pro Ile Ala Gln Asn Gln 
        195                 200                 205             


Thr Thr Leu Gly Ser Ser Arg Ala Lys Leu Gly Asn Phe Pro Trp Gln 
    210                 215                 220                 


Ala Phe Thr Ser Ile His Gly Arg Gly Gly Gly Ala Leu Leu Gly Asp 
225                 230                 235                 240 


Arg Trp Ile Leu Thr Ala Ala His Thr Val Tyr Pro Lys Asp Ser Val 
                245                 250                 255     


Ser Leu Arg Lys Asn Gln Ser Val Asn Val Phe Leu Gly His Thr Ala 
            260                 265                 270         


Ile Asp Glu Met Leu Lys Leu Gly Asn His Pro Val His Arg Val Val 
        275                 280                 285             


Val His Pro Asp Tyr Arg Gln Asn Glu Ser His Asn Phe Ser Gly Asp 
    290                 295                 300                 


Ile Ala Leu Leu Glu Leu Gln His Ser Ile Pro Leu Gly Pro Asn Val 
305                 310                 315                 320 


Leu Pro Val Cys Leu Pro Asp Asn Glu Thr Leu Tyr Arg Ser Gly Leu 
                325                 330                 335     


Leu Gly Tyr Val Ser Gly Phe Gly Met Glu Met Gly Trp Leu Thr Thr 
            340                 345                 350         


Glu Leu Lys Tyr Ser Arg Leu Pro Val Ala Pro Arg Glu Ala Cys Asn 
        355                 360                 365             


Ala Trp Leu Gln Lys Arg Gln Arg Pro Glu Val Phe Ser Asp Asn Met 
    370                 375                 380                 


Phe Cys Val Gly Asp Glu Thr Gln Arg His Ser Val Cys Gln Gly Asp 
385                 390                 395                 400 


Ser Gly Ser Val Tyr Val Val Trp Asp Asn His Ala His His Trp Val 
                405                 410                 415     


Ala Thr Gly Ile Val Ser Trp Gly Ile Gly Cys Gly Glu Gly Tyr Asp 
            420                 425                 430         


Phe Tyr Thr Lys Val Leu Ser Tyr Val Asp Trp Ile Lys Gly Val Met 
        435                 440                 445             


Asn Gly Lys Asn 
    450         


<210>  3001
<211>  66
<212>  PRT
<213>  Homo Sapiens

<400>  3001

Ser Glu Glu Ala Pro Leu Arg Thr Gly Leu Glu Asp Leu Gln Asp Leu 
1               5                   10                  15      


Asp Ser Leu Asp Thr Glu Lys Ser Pro Leu Tyr Gly Leu Gln Ser Arg 
            20                  25                  30          


Val Glu Glu Leu Val Glu Ala Pro Arg Ala Gln Gly Asp Arg Gly Pro 
        35                  40                  45              


Arg Ala Val Phe Leu Leu Thr Arg Trp Arg Lys Phe Trp Gly Ala Pro 
    50                  55                  60                  


Val Thr 
65      


<210>  3002
<211>  227
<212>  PRT
<213>  Homo Sapiens

<400>  3002

Ile Ile Gly Gly His Thr Cys Thr Arg Ser Ser Gln Pro Trp Gln Ala 
1               5                   10                  15      


Ala Leu Leu Ala Gly Pro Arg Arg Arg Phe Leu Cys Gly Gly Ala Leu 
            20                  25                  30          


Leu Ser Gly Gln Trp Val Ile Thr Ala Ala His Cys Gly Arg Pro Ile 
        35                  40                  45              


Leu Gln Val Ala Leu Gly Lys His Asn Leu Arg Arg Trp Glu Ala Thr 
    50                  55                  60                  


Gln Gln Val Leu Arg Val Val Arg Gln Val Thr His Pro Asn Tyr Asn 
65                  70                  75                  80  


Ser Arg Thr His Asp Asn Asp Leu Met Leu Leu Gln Leu Gln Gln Pro 
                85                  90                  95      


Ala Arg Ile Gly Arg Ala Val Arg Pro Ile Glu Val Thr Gln Ala Cys 
            100                 105                 110         


Ala Ser Pro Gly Thr Ser Cys Arg Val Ser Gly Trp Gly Thr Ile Ser 
        115                 120                 125             


Ser Pro Ile Ala Arg Tyr Pro Ala Ser Leu Gln Cys Val Asn Ile Asn 
    130                 135                 140                 


Ile Ser Pro Asp Glu Val Cys Gln Lys Ala Tyr Pro Arg Thr Ile Thr 
145                 150                 155                 160 


Pro Gly Met Val Cys Ala Gly Val Pro Gln Gly Gly Lys Asp Ser Cys 
                165                 170                 175     


Gln Gly Asp Ser Gly Gly Pro Leu Val Cys Arg Gly Gln Leu Gln Gly 
            180                 185                 190         


Leu Val Ser Trp Gly Met Glu Arg Cys Ala Leu Pro Gly Tyr Pro Gly 
        195                 200                 205             


Val Tyr Thr Asn Leu Cys Lys Tyr Arg Ser Trp Ile Glu Glu Thr Met 
    210                 215                 220                 


Arg Asp Lys 
225         


<210>  3003
<211>  189
<212>  PRT
<213>  Homo Sapiens

<400>  3003

Ser Ala Tyr Tyr Tyr Thr Lys Val Met Ser Glu Leu Phe Leu His Thr 
1               5                   10                  15      


Pro Ser Asp Thr Gly Val Ser Phe Gln Ala Ile Ser Ser Met Ala Asp 
            20                  25                  30          


Phe Trp Asp Phe Ala Gln Gly Pro Leu Leu Asp Ser Leu Tyr Trp Thr 
        35                  40                  45              


Lys Trp Tyr Asn Asn Gln Ser Leu Gly His Gly Ser His Ser Phe Ile 
    50                  55                  60                  


Tyr Tyr Glu Asn Met Leu Leu Gly Val Pro Arg Leu Arg Gln Leu Lys 
65                  70                  75                  80  


Val Arg Asn Asp Ser Cys Val Val His Glu Asp Phe Arg Glu Asp Ile 
                85                  90                  95      


Leu Ser Cys Tyr Asp Val Tyr Ser Pro Asp Lys Glu Glu Gln Leu Pro 
            100                 105                 110         


Phe Gly Pro Phe Asn Gly Thr Ala Trp Thr Tyr His Ser Gln Asp Glu 
        115                 120                 125             


Leu Gly Gly Phe Ser His Trp Gly Arg Leu Thr Ser Tyr Ser Gly Gly 
    130                 135                 140                 


Gly Tyr Tyr Leu Asp Leu Pro Gly Ser Arg Gln Gly Ser Ala Glu Ala 
145                 150                 155                 160 


Leu Arg Ala Leu Gln Glu Gly Leu Trp Leu Asp Arg Gly Thr Arg Val 
                165                 170                 175     


Val Phe Ile Asp Phe Ser Val Tyr Asn Ala Asn Ile Asn 
            180                 185                 


<210>  3004
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  3004

Trp Tyr Cys Tyr Gly Leu Cys Ala Pro Ala Pro Gln Met Leu Arg His 
1               5                   10                  15      


Gln Gly Leu Leu Lys Cys Arg Cys Arg Met Leu Phe Asn Asp Leu Lys 
            20                  25                  30          


Val Phe Leu Leu Arg Arg Pro Pro Gln Ala Pro Leu Pro Met His Gly 
        35                  40                  45              


Asp Pro Gln Pro Pro Gly Leu Ala Ala Asn Asn Thr Leu Pro Ala Leu 
    50                  55                  60                  


Gly Ala Gly Gly Trp Ala Gly Trp Arg Gly Pro Arg Glu Val Val Gly 
65                  70                  75                  80  


Arg Glu Pro Pro Pro Val Pro Pro Pro Pro Pro Leu Pro Pro Ser Ser 
                85                  90                  95      


Val Glu Asp Asp Trp Gly Gly Pro Ala Thr Glu Pro Pro Ala Ser Leu 
            100                 105                 110         


Leu Ser Ser Ala Ser Ser Asp Asp Phe Cys Lys Glu Lys Thr Glu Asp 
        115                 120                 125             


Arg Tyr Ser Leu Gly Ser Ser Leu Asp Ser Gly Met Arg Thr Pro Leu 
    130                 135                 140                 


Cys Arg Ile Cys Phe Gln Gly Pro Glu Gln Gly Glu Leu Leu Ser Pro 
145                 150                 155                 160 


Cys Arg Cys Asp Gly Ser Val Lys Cys Thr His Gln Pro Cys Leu Ile 
                165                 170                 175     


Lys Trp Ile Ser Glu Arg Gly Cys Trp Ser Cys Glu Leu Cys Tyr Tyr 
            180                 185                 190         


Lys Tyr His Val Ile Ala Ile Ser Thr Lys Asn Pro Leu Gln Trp Gln 
        195                 200                 205             


Ala Ile Ser Leu Thr Val Ile Glu Lys Val Gln 
    210                 215                 


<210>  3005
<211>  798
<212>  PRT
<213>  Homo Sapiens

<400>  3005

Leu Pro Glu Leu Ser Pro Gln Lys Tyr Phe Ser Thr Leu Gln Pro Gly 
1               5                   10                  15      


Lys Ala Ser Leu Ala Tyr Phe Cys Gln Ala Asp Ser Pro Arg Thr Ser 
            20                  25                  30          


Val Phe Leu Glu Glu Leu Asn Glu Ala Val Arg Pro Leu Gln Asp Tyr 
        35                  40                  45              


Gly Ile Ser Val Ala Lys Val Asn Cys Val Lys Glu Glu Ile Ser Arg 
    50                  55                  60                  


Tyr Cys Gly Lys Glu Lys Asp Leu Met Lys Ala Tyr Leu Phe Lys Gly 
65                  70                  75                  80  


Asn Ile Leu Leu Arg Glu Phe Pro Thr Asp Thr Leu Phe Asp Val Asn 
                85                  90                  95      


Ala Ile Val Ala His Val Leu Phe Ala Leu Leu Phe Ser Glu Val Lys 
            100                 105                 110         


Tyr Ile Thr Asn Leu Glu Asp Leu Gln Asn Ile Glu Asn Ala Leu Lys 
        115                 120                 125             


Gly Lys Ala Asn Ile Ile Phe Ser Tyr Val Arg Ala Ile Gly Ile Pro 
    130                 135                 140                 


Glu His Arg Ala Val Met Glu Ala Ala Phe Val Tyr Gly Thr Thr Tyr 
145                 150                 155                 160 


Gln Phe Val Leu Thr Thr Glu Ile Ala Leu Leu Glu Ser Ile Gly Ser 
                165                 170                 175     


Glu Asp Val Glu Tyr Ala His Leu Tyr Phe Phe His Cys Lys Leu Val 
            180                 185                 190         


Leu Asp Leu Thr Gln Gln Cys Arg Arg Thr Leu Met Glu Gln Pro Leu 
        195                 200                 205             


Thr Thr Leu Asn Ile His Leu Phe Ile Lys Thr Met Lys Ala Pro Leu 
    210                 215                 220                 


Leu Thr Glu Val Ala Glu Asp Pro Gln Gln Val Ser Thr Val His Leu 
225                 230                 235                 240 


Gln Leu Gly Leu Pro Leu Val Phe Ile Val Ser Gln Gln Ala Thr Tyr 
                245                 250                 255     


Glu Ala Asp Arg Arg Thr Ala Glu Trp Val Ala Trp Arg Leu Leu Gly 
            260                 265                 270         


Lys Ala Gly Val Leu Leu Leu Leu Arg Asp Ser Leu Glu Val Asn Ile 
        275                 280                 285             


Pro Gln Asp Ala Asn Val Val Phe Lys Arg Ala Glu Glu Gly Val Pro 
    290                 295                 300                 


Val Glu Phe Leu Val Leu His Asp Val Asp Leu Ile Ile Ser His Val 
305                 310                 315                 320 


Glu Asn Asn Met His Ile Glu Glu Ile Gln Glu Asp Glu Asp Asn Asp 
                325                 330                 335     


Met Glu Gly Pro Asp Ile Asp Val Gln Asp Asp Glu Val Ala Glu Thr 
            340                 345                 350         


Val Phe Arg Asp Arg Lys Arg Lys Leu Pro Leu Glu Leu Thr Val Glu 
        355                 360                 365             


Leu Thr Glu Glu Thr Phe Asn Ala Thr Val Met Ala Ser Asp Ser Ile 
    370                 375                 380                 


Val Leu Phe Tyr Ala Gly Trp Gln Ala Val Ser Met Ala Phe Leu Gln 
385                 390                 395                 400 


Ser Tyr Ile Asp Val Ala Val Lys Leu Lys Gly Thr Ser Thr Met Leu 
                405                 410                 415     


Leu Thr Arg Ile Asn Cys Ala Asp Trp Ser Asp Val Cys Thr Lys Gln 
            420                 425                 430         


Asn Val Thr Glu Phe Pro Ile Ile Lys Met Tyr Lys Lys Gly Glu Asn 
        435                 440                 445             


Pro Val Ser Tyr Ala Gly Met Leu Gly Thr Lys Asp Leu Leu Lys Phe 
    450                 455                 460                 


Ile Gln Leu Asn Arg Ile Ser Tyr Pro Val Asn Ile Thr Ser Ile Gln 
465                 470                 475                 480 


Glu Ala Glu Glu Tyr Leu Ser Gly Glu Leu Tyr Lys Asp Leu Ile Leu 
                485                 490                 495     


Tyr Ser Ser Val Ser Val Leu Gly Leu Phe Ser Pro Thr Met Lys Thr 
            500                 505                 510         


Ala Lys Glu Asp Phe Ser Glu Ala Gly Asn Tyr Leu Lys Gly Tyr Val 
        515                 520                 525             


Ile Thr Gly Ile Tyr Ser Glu Glu Asp Val Leu Leu Leu Ser Thr Lys 
    530                 535                 540                 


Tyr Ala Ala Ser Leu Pro Ala Leu Leu Leu Ala Arg His Thr Glu Gly 
545                 550                 555                 560 


Lys Ile Glu Ser Ile Pro Leu Ala Ser Thr His Ala Gln Asp Ile Val 
                565                 570                 575     


Gln Ile Ile Thr Asp Ala Leu Leu Glu Met Phe Pro Glu Ile Thr Val 
            580                 585                 590         


Glu Asn Leu Pro Ser Tyr Phe Arg Leu Gln Lys Pro Leu Leu Ile Leu 
        595                 600                 605             


Phe Ser Asp Gly Thr Val Asn Pro Gln Tyr Lys Lys Ala Ile Leu Thr 
    610                 615                 620                 


Leu Val Lys Gln Lys Tyr Leu Asp Ser Phe Thr Pro Cys Trp Leu Asn 
625                 630                 635                 640 


Leu Lys Asn Thr Pro Val Gly Arg Gly Ile Leu Arg Ala Tyr Phe Asp 
                645                 650                 655     


Pro Leu Pro Pro Leu Pro Leu Leu Val Leu Val Asn Leu His Ser Gly 
            660                 665                 670         


Gly Gln Val Phe Ala Phe Pro Ser Asp Gln Ala Ile Ile Glu Glu Asn 
        675                 680                 685             


Leu Val Leu Trp Leu Lys Lys Leu Glu Ala Gly Leu Glu Asn His Ile 
    690                 695                 700                 


Thr Ile Leu Pro Ala Gln Glu Trp Lys Pro Pro Leu Pro Ala Tyr Asp 
705                 710                 715                 720 


Phe Leu Ser Met Ile Asp Ala Ala Thr Ser Gln Arg Gly Thr Arg Lys 
                725                 730                 735     


Val Pro Lys Cys Met Lys Glu Thr Asp Val Gln Glu Asn Asp Lys Glu 
            740                 745                 750         


Gln His Glu Asp Lys Ser Ala Val Arg Lys Glu Pro Ile Glu Thr Leu 
        755                 760                 765             


Arg Ile Lys His Trp Asn Arg Ser Asn Trp Phe Lys Glu Ala Glu Lys 
    770                 775                 780                 


Ser Phe Arg Arg Asp Lys Glu Leu Gly Cys Ser Lys Val Asn 
785                 790                 795             


<210>  3006
<211>  60
<212>  PRT
<213>  Homo Sapiens

<400>  3006

Ala Pro Ala His Arg Gly Arg Gly Gly Trp Thr Leu Asn Ser Ala Gly 
1               5                   10                  15      


Tyr Leu Leu Gly Pro Val Leu His Leu Pro Gln Met Gly Asp Gln Asp 
            20                  25                  30          


Gly Lys Arg Glu Thr Ala Leu Glu Ile Leu Asp Leu Trp Lys Ala Ile 
        35                  40                  45              


Asp Gly Leu Pro Tyr Ser His Pro Pro Gln Pro Ser 
    50                  55                  60  


<210>  3007
<211>  198
<212>  PRT
<213>  Homo Sapiens

<400>  3007

Leu Asn Arg Thr Gly Asp Pro Gly Pro Gly Pro Ser Ile Gln Lys Thr 
1               5                   10                  15      


Tyr Asp Leu Thr His Tyr Leu Glu His Gln Leu Arg Ser Leu Ala Gly 
            20                  25                  30          


Thr Tyr Leu Asn Tyr Leu Gly Pro Pro Phe Asn Glu Pro Asp Phe Asn 
        35                  40                  45              


Pro Pro Arg Leu Gly Ala Glu Thr Leu Pro Arg Ala Thr Val Asp Leu 
    50                  55                  60                  


Glu Val Trp Arg Ser Leu Asn Asp Lys Leu Arg Leu Thr Gln Asn Tyr 
65                  70                  75                  80  


Glu Ala Tyr Ser His Leu Leu Cys Tyr Leu Arg Gly Leu Asn Arg Gln 
                85                  90                  95      


Ala Ala Thr Ala Glu Leu Arg Arg Ser Leu Ala His Phe Cys Thr Ser 
            100                 105                 110         


Leu Gln Gly Leu Leu Gly Ser Ile Ala Gly Val Met Ala Ala Leu Gly 
        115                 120                 125             


Tyr Pro Leu Pro Gln Pro Leu Pro Gly Thr Glu Pro Thr Trp Thr Pro 
    130                 135                 140                 


Gly Pro Ala His Ser Asp Phe Leu Gln Lys Met Asp Asp Phe Trp Leu 
145                 150                 155                 160 


Leu Lys Glu Leu Gln Thr Trp Leu Trp Arg Ser Ala Lys Asp Phe Asn 
                165                 170                 175     


Arg Leu Lys Lys Lys Met Gln Pro Pro Ala Ala Ala Val Thr Leu His 
            180                 185                 190         


Leu Gly Ala His Gly Phe 
        195             


<210>  3008
<211>  77
<212>  PRT
<213>  Homo Sapiens

<400>  3008

Asp Tyr Trp Leu Tyr Ser Ser Ala His Ile Cys Asn Gly Thr Asn Leu 
1               5                   10                  15      


Thr Met Asp Asp Gly Pro Pro Pro Arg Arg Ala Arg Gly Asp Leu Thr 
            20                  25                  30          


His Ser Gly Leu Trp Arg Val Cys Cys Ile Glu Gly Ile Tyr Lys Gly 
        35                  40                  45              


His Cys Phe Arg Ile Asn His Phe Pro Glu Asp Asn Asp Tyr Asp His 
    50                  55                  60                  


Asp Ser Ser Glu Tyr Leu Leu Arg Ile Val Arg Ala Ser 
65                  70                  75          


<210>  3009
<211>  67
<212>  PRT
<213>  Homo Sapiens

<400>  3009

Gly Leu Asn Gln Leu Tyr Phe Tyr Tyr Glu Glu Thr Lys Gly Leu Thr 
1               5                   10                  15      


Cys Lys Gly Ile Arg Cys Glu Lys Gln Asn Asn Ala Phe Ser Thr Leu 
            20                  25                  30          


Phe Glu Thr Leu Gln Ser Leu Phe Trp Ser Ile Phe Gly Leu Ile Asn 
        35                  40                  45              


Leu Tyr Val Thr Asn Val Lys Ala Gln His Glu Phe Thr Glu Phe Val 
    50                  55                  60                  


Gly Ala Thr 
65          


<210>  3010
<211>  329
<212>  PRT
<213>  Homo Sapiens

<400>  3010

Ala Pro Ala Pro Thr Ala Thr Ser Ala Pro Val Lys Pro Gly Pro Ala 
1               5                   10                  15      


Leu Ser Tyr Pro Gln Glu Glu Ala Thr Leu Asn Glu Met Phe Arg Glu 
            20                  25                  30          


Val Glu Glu Leu Met Glu Asp Thr Gln His Lys Leu Arg Ser Ala Val 
        35                  40                  45              


Glu Glu Met Glu Ala Glu Glu Ala Ala Ala Lys Ala Ser Ser Glu Val 
    50                  55                  60                  


Asn Leu Ala Asn Leu Pro Pro Ser Tyr His Asn Glu Thr Asn Thr Asp 
65                  70                  75                  80  


Thr Lys Val Gly Asn Asn Thr Ile His Val His Arg Glu Ile His Lys 
                85                  90                  95      


Ile Thr Asn Asn Gln Thr Gly Gln Met Val Phe Ser Glu Thr Val Ile 
            100                 105                 110         


Thr Ser Val Gly Asp Glu Glu Gly Arg Arg Ser His Glu Cys Ile Ile 
        115                 120                 125             


Asp Glu Asp Cys Gly Pro Ser Met Tyr Cys Gln Phe Ala Ser Phe Gln 
    130                 135                 140                 


Tyr Thr Cys Gln Pro Cys Arg Gly Gln Arg Met Leu Cys Thr Arg Asp 
145                 150                 155                 160 


Ser Glu Cys Cys Gly Asp Gln Leu Cys Val Trp Gly His Cys Thr Lys 
                165                 170                 175     


Met Ala Thr Arg Gly Ser Asn Gly Thr Ile Cys Asp Asn Gln Arg Asp 
            180                 185                 190         


Cys Gln Pro Gly Leu Cys Cys Ala Phe Gln Arg Gly Leu Leu Phe Pro 
        195                 200                 205             


Val Cys Thr Pro Leu Pro Val Glu Gly Glu Leu Cys His Asp Pro Ala 
    210                 215                 220                 


Ser Arg Leu Leu Asp Leu Ile Thr Trp Glu Leu Glu Pro Asp Gly Ala 
225                 230                 235                 240 


Leu Asp Arg Cys Pro Cys Ala Ser Gly Leu Leu Cys Gln Pro His Ser 
                245                 250                 255     


His Ser Leu Val Tyr Val Cys Lys Pro Thr Phe Val Gly Ser Arg Asp 
            260                 265                 270         


Gln Asp Gly Glu Ile Leu Leu Pro Arg Glu Val Pro Asp Glu Tyr Glu 
        275                 280                 285             


Val Gly Ser Phe Met Glu Glu Val Arg Gln Glu Leu Glu Asp Leu Glu 
    290                 295                 300                 


Arg Ser Leu Thr Glu Glu Met Ala Leu Gly Glu Pro Ala Ala Ala Ala 
305                 310                 315                 320 


Ala Ala Leu Leu Gly Gly Glu Glu Ile 
                325                 


<210>  3011
<211>  242
<212>  PRT
<213>  Homo Sapiens

<400>  3011

Leu Pro Lys Ser Trp Asp Trp Arg Asn Val Asp Gly Val Asn Tyr Ala 
1               5                   10                  15      


Ser Ile Thr Arg Asn Gln His Ile Pro Gln Tyr Cys Gly Ser Cys Trp 
            20                  25                  30          


Ala His Ala Ser Thr Ser Ala Met Ala Asp Arg Ile Asn Ile Lys Arg 
        35                  40                  45              


Lys Gly Ala Trp Pro Ser Thr Leu Leu Ser Val Gln Asn Val Ile Asp 
    50                  55                  60                  


Cys Gly Asn Ala Gly Ser Cys Glu Gly Gly Asn Asp Leu Ser Val Trp 
65                  70                  75                  80  


Asp Tyr Ala His Gln His Gly Ile Pro Asp Glu Thr Cys Asn Asn Tyr 
                85                  90                  95      


Gln Ala Lys Asp Gln Glu Cys Asp Lys Phe Asn Gln Cys Gly Thr Cys 
            100                 105                 110         


Asn Glu Phe Lys Glu Cys His Ala Ile Arg Asn Tyr Thr Leu Trp Arg 
        115                 120                 125             


Val Gly Asp Tyr Gly Ser Leu Ser Gly Arg Glu Lys Met Met Ala Glu 
    130                 135                 140                 


Ile Tyr Ala Asn Gly Pro Ile Ser Cys Gly Ile Met Ala Thr Glu Arg 
145                 150                 155                 160 


Leu Ala Asn Tyr Thr Gly Gly Ile Tyr Ala Glu Tyr Gln Asp Thr Thr 
                165                 170                 175     


Tyr Ile Asn His Val Val Ser Val Ala Gly Trp Gly Ile Ser Asp Gly 
            180                 185                 190         


Thr Glu Tyr Trp Ile Val Arg Asn Ser Trp Gly Glu Pro Trp Gly Glu 
        195                 200                 205             


Arg Gly Trp Leu Arg Ile Val Thr Ser Thr Tyr Lys Asp Gly Lys Gly 
    210                 215                 220                 


Ala Arg Tyr Asn Leu Ala Ile Glu Glu His Cys Thr Phe Gly Asp Pro 
225                 230                 235                 240 


Ile Val 
        


<210>  3012
<211>  200
<212>  PRT
<213>  Homo Sapiens

<400>  3012

Ser Lys Ser Tyr Tyr Asp Ile Leu Gly Val Pro Lys Ser Ala Ser Glu 
1               5                   10                  15      


Arg Gln Ile Lys Lys Ala Phe His Lys Leu Ala Met Lys Tyr His Pro 
            20                  25                  30          


Asp Lys Asn Lys Ser Pro Asp Ala Glu Ala Lys Phe Arg Glu Ile Ala 
        35                  40                  45              


Glu Ala Tyr Glu Thr Leu Ser Asp Ala Asn Arg Arg Lys Glu Tyr Asp 
    50                  55                  60                  


Thr Leu Gly His Ser Ala Phe Thr Ser Gly Lys Gly Gln Arg Gly Ser 
65                  70                  75                  80  


Gly Ser Ser Phe Glu Gln Ser Phe Asn Phe Asn Phe Asp Asp Leu Phe 
                85                  90                  95      


Lys Asp Phe Gly Phe Phe Gly Gln Asn Gln Asn Thr Gly Ser Lys Lys 
            100                 105                 110         


Arg Phe Glu Asn His Phe Gln Thr Arg Gln Asp Gly Gly Ser Ser Arg 
        115                 120                 125             


Gln Arg His His Phe Gln Glu Phe Ser Phe Gly Gly Gly Leu Phe Asp 
    130                 135                 140                 


Asp Met Phe Glu Asp Met Glu Lys Met Phe Ser Phe Ser Gly Phe Asp 
145                 150                 155                 160 


Ser Thr Asn Gln His Thr Val Gln Thr Glu Asn Arg Phe His Gly Ser 
                165                 170                 175     


Ser Lys His Cys Arg Thr Val Thr Gln Arg Arg Gly Asn Met Val Thr 
            180                 185                 190         


Thr Tyr Thr Asp Cys Ser Gly Gln 
        195                 200 


<210>  3013
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  3013

Gly Arg Asp Phe Tyr Lys Ile Leu Gly Val Pro Arg Ser Ala Ser Ile 
1               5                   10                  15      


Lys Asp Ile Lys Lys Ala Tyr Arg Lys Leu Ala Leu Gln Leu His Pro 
            20                  25                  30          


Asp Arg Asn Pro Asp Asp Pro Gln Ala Gln Glu Lys Phe Gln Asp Leu 
        35                  40                  45              


Gly Ala Ala Tyr Glu Val Leu Ser Asp Ser Glu Lys Arg Lys Gln Tyr 
    50                  55                  60                  


Asp Thr Tyr Gly Glu Glu Gly Leu Lys Asp Gly His Gln Ser Ser His 
65                  70                  75                  80  


Gly Asp Ile Phe Ser His Phe Phe Gly Asp Phe Gly Phe Met Phe Gly 
                85                  90                  95      


Gly Thr Pro Arg Gln Gln Asp Arg Asn Ile Pro Arg Gly Ser Asp Ile 
            100                 105                 110         


Ile Val Asp Leu Glu Val Thr Leu Glu Glu Val Tyr Ala Gly Asn Phe 
        115                 120                 125             


Val Glu Val Val Arg Asn Lys Pro Val Ala Arg Gln Ala Pro Gly Lys 
    130                 135                 140                 


Arg Lys Cys Asn Cys Arg Gln Glu Met Arg Thr Thr Gln Leu Gly Pro 
145                 150                 155                 160 


Gly Arg Phe Gln Met Thr Gln Glu Val Val Cys Asp Glu Cys Pro Asn 
                165                 170                 175     


Val Lys Leu Val Asn Glu Glu Arg Thr Leu Glu Val Glu Ile Glu Pro 
            180                 185                 190         


Gly Val Arg Asp Gly Met Glu Tyr Pro Phe Ile Gly Glu Gly Glu Pro 
        195                 200                 205             


His Val Asp Gly Glu Pro Gly Asp Leu Arg Phe Arg Ile Lys Val Val 
    210                 215                 220                 


Lys His Pro Ile Phe Glu Arg Arg Gly Asp Asp Leu Tyr Thr Asn Val 
225                 230                 235                 240 


Thr Ile Ser Leu Val Glu Ser Leu Val Gly Phe Glu Met Asp Ile Thr 
                245                 250                 255     


His Leu Asp Gly His Lys Val His Ile Ser Arg Asp Lys Ile Thr Arg 
            260                 265                 270         


Pro Gly Ala Lys Leu Trp Lys Lys Gly Glu Gly Leu Pro Asn Phe Asp 
        275                 280                 285             


Asn Asn Asn Ile Lys Gly Ser Leu Ile Ile Thr Phe Asp Val Asp Phe 
    290                 295                 300                 


Pro Lys Glu Gln Leu Thr Glu Glu Ala Arg Glu Gly Ile Lys Gln Leu 
305                 310                 315                 320 


Leu Lys Gln Gly Ser Val Gln Lys Val Tyr Asn Gly Leu Gln Gly Tyr 
                325                 330                 335     


<210>  3014
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  3014

Leu Val Leu Asp Phe Asn Asn Ile Arg Ser Ser Ala Asp Leu His Gly 
1               5                   10                  15      


Ala Arg Lys Gly Ser Gln Cys Leu Ser Asp Thr Asp Cys Asn Thr Arg 
            20                  25                  30          


Lys Phe Cys Leu Gln Pro Arg Asp Glu Lys Pro Phe Cys Ala Thr Cys 
        35                  40                  45              


Arg Gly Leu Arg Arg Arg Cys Gln Arg Asp Ala Met Cys Cys Pro Gly 
    50                  55                  60                  


Thr Leu Cys Val Asn Asp Val Cys Thr Thr Met Glu Asp Ala Thr Pro 
65                  70                  75                  80  


Ile Leu Glu Arg Gln Leu Asp Glu Gln Asp Gly Thr His Ala Glu Gly 
                85                  90                  95      


Thr Thr Gly His Pro Val Gln Glu Asn Gln Pro Lys Arg Lys Pro Ser 
            100                 105                 110         


Ile Lys Lys Ser Gln Gly Arg Lys Gly Gln Glu Gly Glu Ser Cys Leu 
        115                 120                 125             


Arg Thr Phe Asp Cys Gly Pro Gly Leu Cys Cys Ala Arg His Phe Trp 
    130                 135                 140                 


Thr Lys Ile Cys Lys Pro Val Leu Leu Glu Gly Gln Val Cys Ser Arg 
145                 150                 155                 160 


Arg Gly His Lys Asp Thr Ala Gln Ala Pro Glu Ile Phe Gln Arg Cys 
                165                 170                 175     


Asp Cys Gly Pro Gly Leu Leu Cys Arg Ser Gln Leu Thr Ser Asn Arg 
            180                 185                 190         


Gln His Ala Arg Leu Arg Val Cys Gln Lys Ile Glu Lys Leu 
        195                 200                 205     


<210>  3015
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  3015

Lys Leu Asn Ser Ile Lys Ser Ser Leu Gly Gly Glu Thr Pro Gly Gln 
1               5                   10                  15      


Ala Ala Asn Arg Ser Ala Gly Met Tyr Gln Gly Leu Ala Phe Gly Gly 
            20                  25                  30          


Ser Lys Lys Gly Lys Asn Leu Gly Gln Ala Tyr Pro Cys Ser Ser Asp 
        35                  40                  45              


Lys Glu Cys Glu Val Gly Arg Tyr Cys His Ser Pro His Gln Gly Ser 
    50                  55                  60                  


Ser Ala Cys Met Val Cys Arg Arg Lys Lys Lys Arg Cys His Arg Asp 
65                  70                  75                  80  


Gly Met Cys Cys Pro Ser Thr Arg Cys Asn Asn Gly Ile Cys Ile Pro 
                85                  90                  95      


Val Thr Glu Ser Ile Leu Thr Pro His Ile Pro Ala Leu Asp Gly Thr 
            100                 105                 110         


Gln His Arg Asp Arg Asn His Gly His Tyr Ser Asn His Asp Leu Gly 
        115                 120                 125             


Trp Gln Asn Leu Gly Arg Pro His Thr Lys Met Ser His Ile Lys Gly 
    130                 135                 140                 


His Glu Gly Asp Pro Cys Leu Arg Ser Ser Asp Cys Ile Glu Gly Phe 
145                 150                 155                 160 


Cys Cys Ala Arg His Phe Trp Thr Lys Ile Cys Lys Pro Val Leu His 
                165                 170                 175     


Gln Gly Glu Val Cys Thr Lys Gln Arg Lys Lys Gly Ser His Gly Leu 
            180                 185                 190         


Glu Ile Phe Gln Arg Cys Asp Cys Ala Lys Gly Leu Ser Cys Lys Val 
        195                 200                 205             


Trp Lys Asp Ala Thr Tyr Ser Ser Lys Ala Arg Leu His Val Cys Gln 
    210                 215                 220                 


Lys Ile 
225     


<210>  3016
<211>  336
<212>  PRT
<213>  Homo Sapiens

<400>  3016

Asn Trp Met Trp Leu Gly Ile Ala Ser Phe Gly Val Pro Glu Lys Leu 
1               5                   10                  15      


Gly Cys Ala Asn Leu Pro Leu Asn Ser Arg Gln Lys Glu Leu Cys Lys 
            20                  25                  30          


Arg Lys Pro Tyr Leu Leu Pro Ser Ile Arg Glu Gly Ala Arg Leu Gly 
        35                  40                  45              


Ile Gln Glu Cys Gly Ser Gln Phe Arg His Glu Arg Trp Asn Cys Met 
    50                  55                  60                  


Ile Thr Ala Ala Ala Thr Thr Ala Pro Met Gly Ala Ser Pro Leu Phe 
65                  70                  75                  80  


Gly Tyr Glu Leu Ser Ser Gly Thr Lys Glu Thr Ala Phe Ile Tyr Ala 
                85                  90                  95      


Val Met Ala Ala Gly Leu Val His Ser Val Thr Arg Ser Cys Ser Ala 
            100                 105                 110         


Gly Asn Met Thr Glu Cys Ser Cys Asp Thr Thr Leu Gln Asn Gly Gly 
        115                 120                 125             


Ser Ala Ser Glu Gly Trp His Trp Gly Gly Cys Ser Asp Asp Val Gln 
    130                 135                 140                 


Tyr Gly Met Trp Phe Ser Arg Lys Phe Leu Asp Phe Pro Ile Gly Asn 
145                 150                 155                 160 


Thr Thr Gly Lys Glu Asn Lys Val Leu Leu Ala Met Asn Leu His Asn 
                165                 170                 175     


Asn Glu Ala Gly Arg Gln Ala Val Ala Lys Leu Met Ser Val Asp Cys 
            180                 185                 190         


Arg Cys His Gly Val Ser Gly Ser Cys Ala Val Lys Thr Cys Trp Lys 
        195                 200                 205             


Thr Met Ser Ser Phe Glu Lys Ile Gly His Leu Leu Lys Asp Lys Tyr 
    210                 215                 220                 


Glu Asn Ser Ile Gln Ile Ser Asp Lys Thr Lys Arg Lys Met Arg Arg 
225                 230                 235                 240 


Arg Glu Lys Asp Gln Arg Lys Ile Pro Ile His Lys Asp Asp Leu Leu 
                245                 250                 255     


Tyr Val Asn Lys Ser Pro Asn Tyr Cys Val Glu Asp Lys Lys Leu Gly 
            260                 265                 270         


Ile Pro Gly Thr Gln Gly Arg Glu Cys Asn Arg Thr Ser Glu Gly Ala 
        275                 280                 285             


Asp Gly Cys Asn Leu Leu Cys Cys Gly Arg Gly Tyr Asn Thr His Val 
    290                 295                 300                 


Val Arg His Val Glu Arg Cys Glu Cys Lys Phe Ile Trp Cys Cys Tyr 
305                 310                 315                 320 


Val Arg Cys Arg Arg Cys Glu Ser Met Thr Asp Val His Thr Cys Lys 
                325                 330                 335     


<210>  3017
<211>  456
<212>  PRT
<213>  Homo Sapiens

<400>  3017

Val Gln Val Leu Asn Leu Gln Ala Arg Leu Arg Val Leu Glu Met Tyr 
1               5                   10                  15      


Phe Leu Asn Asp Thr Leu Ala Ala Glu Asp Ser Pro Ser Phe Ser Leu 
            20                  25                  30          


Leu Gln Ser Ala His Pro Gly Glu His Leu Ala Gln Gly Ala Ser Arg 
        35                  40                  45              


Leu Gln Val Leu Gln Ala Gln Leu Thr Trp Val Arg Val Ser His Glu 
    50                  55                  60                  


His Leu Leu Gln Arg Val Asp Asn Phe Thr Gln Asn Pro Gly Met Phe 
65                  70                  75                  80  


Arg Ile Lys Gly Glu Gln Gly Ala Pro Gly Leu Gln Gly His Lys Gly 
                85                  90                  95      


Ala Met Gly Met Pro Gly Ala Pro Gly Pro Pro Gly Pro Pro Ala Glu 
            100                 105                 110         


Lys Gly Ala Lys Gly Ala Met Gly Arg Asp Gly Ala Thr Gly Pro Ser 
        115                 120                 125             


Gly Pro Gln Gly Pro Pro Gly Val Lys Gly Glu Ala Gly Leu Gln Gly 
    130                 135                 140                 


Pro Gln Gly Ala Pro Gly Lys Gln Gly Ala Thr Gly Thr Pro Gly Pro 
145                 150                 155                 160 


Gln Gly Glu Lys Gly Ser Lys Gly Asp Gly Gly Leu Ile Gly Pro Lys 
                165                 170                 175     


Gly Glu Thr Gly Thr Lys Gly Glu Lys Gly Asp Leu Gly Leu Pro Gly 
            180                 185                 190         


Ser Lys Gly Asp Arg Gly Met Lys Gly Asp Ala Gly Val Met Gly Pro 
        195                 200                 205             


Pro Gly Ala Gln Gly Ser Lys Gly Asp Phe Gly Arg Pro Gly Pro Pro 
    210                 215                 220                 


Gly Leu Ala Gly Phe Pro Gly Ala Lys Gly Asp Gln Gly Gln Pro Gly 
225                 230                 235                 240 


Leu Gln Gly Val Pro Gly Pro Pro Gly Ala Val Gly His Pro Gly Ala 
                245                 250                 255     


Lys Gly Glu Pro Gly Ser Ala Gly Ser Pro Gly Arg Ala Gly Leu Pro 
            260                 265                 270         


Gly Ser Pro Gly Ser Pro Gly Ala Thr Gly Leu Lys Gly Ser Lys Gly 
        275                 280                 285             


Asp Thr Gly Leu Gln Gly Gln Gln Gly Arg Lys Gly Glu Ser Gly Val 
    290                 295                 300                 


Pro Gly Pro Ala Gly Val Lys Gly Glu Gln Gly Ser Pro Gly Leu Ala 
305                 310                 315                 320 


Gly Pro Lys Gly Ala Pro Gly Gln Ala Gly Gln Lys Gly Asp Gln Gly 
                325                 330                 335     


Val Lys Gly Ser Ser Gly Glu Gln Gly Val Lys Gly Glu Lys Gly Glu 
            340                 345                 350         


Arg Gly Glu Asn Ser Val Ser Val Arg Ile Val Gly Ser Ser Asn Arg 
        355                 360                 365             


Gly Arg Ala Glu Val Tyr Tyr Ser Gly Thr Trp Gly Thr Ile Cys Asp 
    370                 375                 380                 


Asp Glu Trp Gln Asn Ser Asp Ala Ile Val Phe Cys Arg Met Leu Gly 
385                 390                 395                 400 


Tyr Ser Lys Gly Arg Ala Leu Tyr Lys Val Gly Ala Gly Thr Gly Gln 
                405                 410                 415     


Ile Trp Leu Asp Asn Val Gln Cys Arg Gly Thr Glu Ser Thr Leu Trp 
            420                 425                 430         


Ser Cys Thr Lys Asn Ser Trp Gly His His Asp Cys Ser His Glu Glu 
        435                 440                 445             


Asp Ala Gly Val Glu Cys Ser Val 
    450                 455     


<210>  3018
<211>  212
<212>  PRT
<213>  Homo Sapiens

<400>  3018

Ala Asp Gly Lys Tyr Ala Gln Lys Leu Phe Asn Asp Leu Phe Glu Asp 
1               5                   10                  15      


Tyr Ser Asn Ala Leu Arg Pro Val Glu Asp Thr Asp Lys Val Leu Asn 
            20                  25                  30          


Val Thr Leu Gln Ile Thr Leu Ser Gln Ile Lys Asp Met Asp Glu Arg 
        35                  40                  45              


Asn Gln Ile Leu Thr Ala Tyr Leu Trp Ile Arg Gln Ile Trp His Asp 
    50                  55                  60                  


Ala Tyr Leu Thr Trp Asp Arg Asp Gln Tyr Asp Gly Leu Asp Ser Ile 
65                  70                  75                  80  


Arg Ile Pro Ser Asp Leu Val Trp Arg Pro Asp Ile Val Leu Tyr Asn 
                85                  90                  95      


Lys Ala Asp Asp Glu Ser Ser Glu Pro Val Asn Thr Asn Val Val Leu 
            100                 105                 110         


Arg Tyr Asp Gly Leu Ile Thr Trp Asp Ala Pro Ala Ile Thr Lys Ser 
        115                 120                 125             


Ser Cys Val Val Asp Val Thr Tyr Phe Pro Phe Asp Asn Gln Gln Cys 
    130                 135                 140                 


Asn Leu Thr Phe Gly Ser Trp Thr Tyr Asn Gly Asn Gln Val Asp Ile 
145                 150                 155                 160 


Phe Asn Ala Leu Asp Ser Gly Asp Leu Ser Asp Phe Ile Glu Asp Val 
                165                 170                 175     


Glu Trp Glu Val His Gly Met Pro Ala Val Lys Asn Val Ile Ser Tyr 
            180                 185                 190         


Gly Cys Cys Ser Glu Pro Tyr Pro Asp Val Thr Phe Thr Leu Leu Leu 
        195                 200                 205             


Lys Arg Arg Ser 
    210         


<210>  3019
<211>  380
<212>  PRT
<213>  Homo Sapiens

<400>  3019

Glu Arg Val Arg Tyr Tyr Arg Glu Phe His His Gln Thr Ala Leu Asp 
1               5                   10                  15      


Glu Arg Glu Ser His Arg Leu Ile Phe Pro Ala Val Thr Leu Cys Asn 
            20                  25                  30          


Ile Asn Pro Leu Arg Arg Ser Arg Leu Thr Pro Asn Asp Leu His Trp 
        35                  40                  45              


Ala Gly Ser Ala Leu Leu Gly Leu Asp Pro Ala Glu His Ala Ala Phe 
    50                  55                  60                  


Leu Arg Ala Leu Gly Arg Pro Pro Ala Pro Pro Gly Phe Met Pro Ser 
65                  70                  75                  80  


Pro Thr Phe Asp Met Ala Gln Leu Tyr Ala Arg Ala Gly His Ser Leu 
                85                  90                  95      


Asp Asp Met Leu Leu Asp Cys Arg Phe Arg Gly Gln Pro Cys Gly Pro 
            100                 105                 110         


Glu Asn Phe Thr Thr Ile Phe Thr Arg Met Gly Lys Cys Tyr Thr Phe 
        115                 120                 125             


Asn Ser Gly Ala Asp Gly Ala Glu Leu Leu Thr Thr Thr Arg Gly Gly 
    130                 135                 140                 


Met Gly Asn Gly Leu Asp Ile Met Leu Asp Val Gln Gln Glu Glu Tyr 
145                 150                 155                 160 


Leu Pro Val Trp Arg Asp Asn Glu Glu Thr Pro Phe Glu Val Gly Ile 
                165                 170                 175     


Arg Val Gln Ile His Ser Gln Glu Glu Pro Pro Ile Ile Asp Gln Leu 
            180                 185                 190         


Gly Leu Gly Val Ser Pro Gly Tyr Gln Thr Phe Val Ser Cys Gln Gln 
        195                 200                 205             


Gln Gln Leu Ser Phe Leu Pro Pro Pro Trp Gly Asp Cys Ser Ser Ala 
    210                 215                 220                 


Ser Leu Asn Pro Asn Tyr Glu Pro Glu Pro Ser Asp Pro Leu Gly Ser 
225                 230                 235                 240 


Pro Ser Pro Ser Pro Ser Pro Pro Tyr Thr Leu Met Gly Cys Arg Leu 
                245                 250                 255     


Ala Cys Glu Thr Arg Tyr Val Ala Arg Lys Cys Gly Cys Arg Met Val 
            260                 265                 270         


Tyr Met Pro Gly Asp Val Pro Val Cys Ser Pro Gln Gln Tyr Lys Asn 
        275                 280                 285             


Cys Ala His Pro Ala Ile Asp Ala Met Leu Arg Lys Asp Ser Cys Ala 
    290                 295                 300                 


Cys Pro Asn Pro Cys Ala Ser Thr Arg Tyr Ala Lys Glu Leu Ser Met 
305                 310                 315                 320 


Val Arg Ile Pro Ser Arg Ala Ala Ala Arg Phe Leu Ala Arg Lys Leu 
                325                 330                 335     


Asn Arg Ser Glu Ala Tyr Ile Ala Glu Asn Val Leu Ala Leu Asp Ile 
            340                 345                 350         


Phe Phe Glu Ala Leu Asn Tyr Glu Thr Val Glu Gln Lys Lys Ala Tyr 
        355                 360                 365             


Glu Met Ser Glu Leu Leu Gly Asp Ile Gly Gly Gln 
    370                 375                 380 


<210>  3020
<211>  478
<212>  PRT
<213>  Homo Sapiens

<400>  3020

Ala Glu Leu Arg Ala Pro Pro Asp Lys Ile Ala Ile Ile Gly Ala Gly 
1               5                   10                  15      


Ile Gly Gly Thr Ser Ala Ala Tyr Tyr Leu Arg Gln Lys Phe Gly Lys 
            20                  25                  30          


Asp Val Lys Ile Asp Leu Phe Glu Arg Glu Glu Val Gly Gly Arg Leu 
        35                  40                  45              


Ala Thr Met Met Val Gln Gly Gln Glu Tyr Glu Ala Gly Gly Ser Val 
    50                  55                  60                  


Ile His Pro Leu Asn Leu His Met Lys Arg Phe Val Lys Asp Leu Gly 
65                  70                  75                  80  


Leu Ser Ala Val Gln Ala Ser Gly Gly Leu Leu Gly Ile Tyr Asn Gly 
                85                  90                  95      


Glu Thr Leu Val Phe Glu Glu Ser Asn Trp Phe Ile Ile Asn Val Ile 
            100                 105                 110         


Lys Leu Val Trp Arg Tyr Gly Phe Gln Ser Leu Arg Met His Met Trp 
        115                 120                 125             


Val Glu Asp Val Leu Asp Lys Phe Met Arg Ile Tyr Arg Tyr Gln Ser 
    130                 135                 140                 


His Asp Tyr Ala Phe Ser Ser Val Glu Lys Leu Leu His Ala Leu Gly 
145                 150                 155                 160 


Gly Asp Asp Phe Leu Gly Met Leu Asn Arg Thr Leu Leu Glu Thr Leu 
                165                 170                 175     


Gln Lys Ala Gly Phe Ser Glu Lys Phe Leu Asn Glu Met Ile Ala Pro 
            180                 185                 190         


Val Met Arg Val Asn Tyr Gly Gln Ser Thr Asp Ile Asn Ala Phe Val 
        195                 200                 205             


Gly Ala Val Ser Leu Ser Cys Ser Asp Ser Gly Leu Trp Ala Val Glu 
    210                 215                 220                 


Gly Gly Asn Lys Leu Val Cys Ser Gly Leu Leu Gln Ala Ser Lys Ser 
225                 230                 235                 240 


Asn Leu Ile Ser Gly Ser Val Met Tyr Ile Glu Glu Lys Thr Lys Thr 
                245                 250                 255     


Lys Tyr Thr Gly Asn Pro Thr Lys Met Tyr Glu Val Val Tyr Gln Ile 
            260                 265                 270         


Gly Thr Glu Thr Arg Ser Asp Phe Tyr Asp Ile Val Leu Val Ala Thr 
        275                 280                 285             


Pro Leu Asn Arg Lys Met Ser Asn Ile Thr Phe Leu Asn Phe Asp Pro 
    290                 295                 300                 


Pro Ile Glu Glu Phe His Gln Tyr Tyr Gln His Ile Val Thr Thr Leu 
305                 310                 315                 320 


Val Lys Gly Glu Leu Asn Thr Ser Ile Phe Ser Ser Arg Pro Ile Asp 
                325                 330                 335     


Lys Phe Gly Leu Asn Thr Val Leu Thr Thr Asp Asn Ser Asp Leu Phe 
            340                 345                 350         


Ile Asn Ser Ile Gly Ile Val Pro Ser Val Arg Glu Lys Glu Asp Pro 
        355                 360                 365             


Glu Pro Ser Thr Asp Gly Thr Tyr Val Trp Lys Ile Phe Ser Gln Glu 
    370                 375                 380                 


Thr Leu Thr Lys Ala Gln Ile Leu Lys Leu Phe Leu Ser Tyr Asp Tyr 
385                 390                 395                 400 


Ala Val Lys Lys Pro Trp Leu Ala Tyr Pro His Tyr Lys Pro Pro Glu 
                405                 410                 415     


Lys Cys Pro Ser Ile Ile Leu His Asp Arg Leu Tyr Tyr Leu Asn Gly 
            420                 425                 430         


Ile Glu Cys Ala Ala Ser Ala Met Glu Met Ser Ala Ile Ala Ala His 
        435                 440                 445             


Asn Ala Ala Leu Leu Ala Tyr His Arg Trp Asn Gly His Thr Asp Met 
    450                 455                 460                 


Ile Asp Gln Asp Gly Leu Tyr Glu Lys Leu Lys Thr Glu Leu 
465                 470                 475             


<210>  3021
<211>  715
<212>  PRT
<213>  Homo Sapiens

<400>  3021

Phe Val Ser Ser His Arg Tyr Val Glu Thr Met Leu Val Ala Asp Gln 
1               5                   10                  15      


Ser Met Ala Glu Phe His Gly Ser Gly Leu Lys His Tyr Leu Leu Thr 
            20                  25                  30          


Leu Phe Ser Val Ala Ala Arg Leu Tyr Lys His Pro Ser Ile Arg Asn 
        35                  40                  45              


Ser Val Ser Leu Val Val Val Lys Ile Leu Val Ile His Asp Glu Gln 
    50                  55                  60                  


Lys Gly Pro Glu Val Thr Ser Asn Ala Ala Leu Thr Leu Arg Asn Phe 
65                  70                  75                  80  


Cys Asn Trp Gln Lys Gln His Asn Pro Pro Ser Asp Arg Asp Ala Glu 
                85                  90                  95      


His Tyr Asp Thr Ala Ile Leu Phe Thr Arg Gln Asp Leu Cys Gly Ser 
            100                 105                 110         


Gln Thr Cys Asp Thr Leu Gly Met Ala Asp Val Gly Thr Val Cys Asp 
        115                 120                 125             


Pro Ser Arg Ser Cys Ser Val Ile Glu Asp Asp Gly Leu Gln Ala Ala 
    130                 135                 140                 


Phe Thr Thr Ala His Glu Leu Gly His Val Phe Asn Met Pro His Asp 
145                 150                 155                 160 


Asp Ala Lys Gln Cys Ala Ser Leu Asn Gly Val Asn Gln Asp Ser His 
                165                 170                 175     


Met Met Ala Ser Met Leu Ser Asn Leu Asp His Ser Gln Pro Trp Ser 
            180                 185                 190         


Pro Cys Ser Ala Tyr Met Ile Thr Ser Phe Leu Asp Asn Gly His Gly 
        195                 200                 205             


Glu Cys Leu Met Asp Lys Pro Gln Asn Pro Ile Gln Leu Pro Gly Asp 
    210                 215                 220                 


Leu Pro Gly Thr Ser Tyr Asp Ala Asn Arg Gln Cys Gln Phe Thr Phe 
225                 230                 235                 240 


Gly Glu Asp Ser Lys His Cys Pro Asp Ala Ala Ser Thr Cys Ser Thr 
                245                 250                 255     


Leu Trp Cys Thr Gly Thr Ser Gly Gly Val Leu Val Cys Gln Thr Lys 
            260                 265                 270         


His Phe Pro Trp Ala Asp Gly Thr Ser Cys Gly Glu Gly Lys Trp Cys 
        275                 280                 285             


Ile Asn Gly Lys Cys Val Asn Lys Thr Asp Arg Lys His Phe Asp Thr 
    290                 295                 300                 


Pro Phe His Gly Ser Trp Gly Met Trp Gly Pro Trp Gly Asp Cys Ser 
305                 310                 315                 320 


Arg Thr Cys Gly Gly Gly Val Gln Tyr Thr Met Arg Glu Cys Asp Asn 
                325                 330                 335     


Pro Val Pro Lys Asn Gly Gly Lys Tyr Cys Glu Gly Lys Arg Val Arg 
            340                 345                 350         


Tyr Arg Ser Cys Asn Leu Glu Asp Cys Pro Asp Asn Asn Gly Lys Thr 
        355                 360                 365             


Phe Arg Glu Glu Gln Cys Glu Ala His Asn Glu Phe Ser Lys Ala Ser 
    370                 375                 380                 


Phe Gly Ser Gly Pro Ala Val Glu Trp Ile Pro Lys Tyr Ala Gly Val 
385                 390                 395                 400 


Ser Pro Lys Asp Arg Cys Lys Leu Ile Cys Gln Ala Lys Gly Ile Gly 
                405                 410                 415     


Tyr Phe Phe Val Leu Gln Pro Lys Val Val Asp Gly Thr Pro Cys Ser 
            420                 425                 430         


Thr Asp Ser Thr Ser Val Cys Val Gln Gly Gln Cys Val Lys Ala Gly 
        435                 440                 445             


Cys Asp Arg Ile Ile Asp Ser Lys Lys Lys Phe Asp Lys Cys Gly Val 
    450                 455                 460                 


Cys Gly Gly Asn Gly Ser Thr Cys Lys Lys Ile Ser Gly Ser Val Thr 
465                 470                 475                 480 


Ser Ala Lys Pro Gly Tyr His Asp Ile Ile Thr Ile Pro Thr Gly Ala 
                485                 490                 495     


Thr Asn Ile Glu Val Lys Gln Arg Asn Gln Arg Gly Ser Arg Asn Asn 
            500                 505                 510         


Gly Ser Phe Leu Ala Ile Lys Ala Ala Asp Gly Thr Tyr Ile Leu Asn 
        515                 520                 525             


Gly Asp Tyr Thr Leu Ser Thr Leu Glu Gln Asp Ile Met Tyr Lys Gly 
    530                 535                 540                 


Val Val Leu Arg Tyr Ser Gly Ser Ser Ala Ala Leu Glu Arg Ile Arg 
545                 550                 555                 560 


Ser Phe Ser Pro Leu Lys Glu Pro Leu Thr Ile Gln Val Leu Thr Val 
                565                 570                 575     


Gly Asn Ala Leu Arg Pro Lys Ile Lys Tyr Thr Tyr Phe Val Lys Lys 
            580                 585                 590         


Lys Lys Glu Ser Phe Asn Ala Ile Pro Thr Phe Ser Ala Trp Val Ile 
        595                 600                 605             


Glu Glu Trp Gly Glu Cys Ser Lys Ser Cys Glu Leu Gly Trp Gln Arg 
    610                 615                 620                 


Arg Leu Val Glu Cys Arg Asp Ile Asn Gly Gln Pro Ala Ser Glu Cys 
625                 630                 635                 640 


Ala Lys Glu Val Lys Pro Ala Ser Thr Arg Pro Cys Ala Asp His Pro 
                645                 650                 655     


Cys Pro Gln Trp Gln Leu Gly Glu Trp Ser Ser Cys Ser Lys Thr Cys 
            660                 665                 670         


Gly Lys Gly Tyr Lys Lys Arg Ser Leu Lys Cys Leu Ser His Asp Gly 
        675                 680                 685             


Gly Val Leu Ser His Glu Ser Cys Asp Pro Leu Lys Lys Pro Lys His 
    690                 695                 700                 


Phe Ile Asp Phe Cys Thr Met Ala Glu Cys Ser 
705                 710                 715 


<210>  3022
<211>  467
<212>  PRT
<213>  Homo Sapiens

<400>  3022

Ala Pro Asp Pro Gly Phe Gln Glu Arg Phe Phe Gln Gln Arg Leu Asp 
1               5                   10                  15      


His Phe Asn Phe Glu Arg Phe Gly Asn Lys Thr Phe Pro Gln Arg Phe 
            20                  25                  30          


Leu Val Ser Asp Arg Phe Trp Val Arg Gly Glu Gly Pro Ile Phe Phe 
        35                  40                  45              


Tyr Thr Gly Asn Glu Gly Asp Val Trp Ala Phe Ala Asn Asn Ser Gly 
    50                  55                  60                  


Phe Val Ala Glu Leu Ala Ala Glu Arg Gly Ala Leu Leu Val Phe Ala 
65                  70                  75                  80  


Glu His Arg Tyr Tyr Gly Lys Ser Leu Pro Phe Gly Ala Gln Ser Thr 
                85                  90                  95      


Gln Arg Gly His Thr Glu Leu Leu Thr Val Glu Gln Ala Leu Ala Asp 
            100                 105                 110         


Phe Ala Glu Leu Leu Arg Ala Leu Arg Arg Asp Leu Gly Ala Gln Asp 
        115                 120                 125             


Ala Pro Ala Ile Ala Phe Gly Gly Ser Tyr Gly Gly Met Leu Ser Ala 
    130                 135                 140                 


Tyr Leu Arg Met Lys Tyr Pro His Leu Val Ala Gly Ala Leu Ala Ala 
145                 150                 155                 160 


Ser Ala Pro Val Leu Ala Val Ala Gly Leu Gly Asp Ser Asn Gln Phe 
                165                 170                 175     


Phe Arg Asp Val Thr Ala Asp Phe Glu Gly Gln Ser Pro Lys Cys Thr 
            180                 185                 190         


Gln Gly Val Arg Glu Ala Phe Arg Gln Ile Lys Asp Leu Phe Leu Gln 
        195                 200                 205             


Gly Ala Tyr Asp Thr Val Arg Trp Glu Phe Gly Thr Cys Gln Pro Leu 
    210                 215                 220                 


Ser Asp Glu Lys Asp Leu Thr Gln Leu Phe Met Phe Ala Arg Asn Ala 
225                 230                 235                 240 


Phe Thr Val Leu Ala Met Met Asp Tyr Pro Tyr Pro Thr Asp Phe Leu 
                245                 250                 255     


Gly Pro Leu Pro Ala Asn Pro Val Lys Val Gly Cys Asp Arg Leu Leu 
            260                 265                 270         


Ser Glu Ala Gln Arg Ile Thr Gly Leu Arg Ala Leu Ala Gly Leu Val 
        275                 280                 285             


Tyr Asn Ala Ser Gly Ser Glu His Cys Tyr Asp Ile Tyr Arg Leu Tyr 
    290                 295                 300                 


His Ser Cys Ala Asp Pro Thr Gly Cys Gly Thr Gly Pro Asp Ala Arg 
305                 310                 315                 320 


Ala Trp Asp Tyr Gln Ala Cys Thr Glu Ile Asn Leu Thr Phe Ala Ser 
                325                 330                 335     


Asn Asn Val Thr Asp Met Phe Pro Asp Leu Pro Phe Thr Asp Glu Leu 
            340                 345                 350         


Arg Gln Arg Tyr Cys Leu Asp Thr Trp Gly Val Trp Pro Arg Pro Asp 
        355                 360                 365             


Trp Leu Leu Thr Ser Phe Trp Gly Gly Asp Leu Arg Ala Ala Ser Asn 
    370                 375                 380                 


Ile Ile Phe Ser Asn Gly Asn Leu Asp Pro Trp Ala Gly Gly Gly Ile 
385                 390                 395                 400 


Arg Arg Asn Leu Ser Ala Ser Val Ile Ala Val Thr Ile Gln Gly Gly 
                405                 410                 415     


Ala His His Leu Asp Leu Arg Ala Ser His Pro Glu Asp Pro Ala Ser 
            420                 425                 430         


Val Val Glu Ala Arg Lys Leu Glu Ala Thr Ile Ile Gly Glu Trp Val 
        435                 440                 445             


Lys Ala Ala Arg Arg Glu Gln Gln Pro Ala Leu Arg Gly Gly Pro Arg 
    450                 455                 460                 


Leu Ser Leu 
465         


<210>  3023
<211>  72
<212>  PRT
<213>  Homo Sapiens

<400>  3023

Met Asn Pro Pro Ser Gly Pro Arg Val Leu Pro Ser Pro Thr Gln Glu 
1               5                   10                  15      


Pro Ser Cys Met Ala Thr Pro Ala Pro Pro Ser Trp Trp Asp Ser Ser 
            20                  25                  30          


Gln Ser Ser Ile Ser Ser Leu Gly Arg Leu Pro Ser Ile Ser Pro Thr 
        35                  40                  45              


Ala Pro Gly Thr Trp Ala Ala Ala Trp Val Pro Leu Pro Thr Val Asp 
    50                  55                  60                  


Val Pro Asp His Ala His Tyr Thr 
65                  70          


<210>  3024
<211>  346
<212>  PRT
<213>  Homo Sapiens

<400>  3024

Ala Gly Glu Ala Pro Gly Ala Leu Ser Thr Ala Asp Pro Ala Asp Gln 
1               5                   10                  15      


Ser Val Gln Cys Val Pro Lys Ala Thr Cys Pro Ser Ser Arg Pro Arg 
            20                  25                  30          


Leu Leu Trp Gln Thr Pro Thr Thr Gln Thr Leu Pro Ser Thr Thr Met 
        35                  40                  45              


Glu Thr Gln Phe Pro Val Ser Glu Gly Lys Val Asp Pro Tyr Arg Ser 
    50                  55                  60                  


Cys Gly Phe Ser Tyr Glu Gln Asp Pro Thr Leu Arg Asp Pro Glu Ala 
65                  70                  75                  80  


Val Ala Arg Arg Trp Pro Trp Met Val Ser Val Arg Ala Asn Gly Thr 
                85                  90                  95      


His Ile Cys Ala Gly Thr Ile Ile Ala Ser Gln Trp Val Leu Thr Val 
            100                 105                 110         


Ala His Cys Leu Ile Trp Arg Asp Val Ile Tyr Ser Val Arg Val Gly 
        115                 120                 125             


Ser Pro Trp Ile Asp Gln Met Thr Gln Thr Ala Ser Asp Val Pro Val 
    130                 135                 140                 


Leu Gln Val Ile Met His Ser Arg Tyr Arg Ala Gln Arg Phe Trp Ser 
145                 150                 155                 160 


Trp Val Gly Gln Ala Asn Asp Ile Gly Leu Leu Lys Leu Lys Gln Glu 
                165                 170                 175     


Leu Lys Tyr Ser Asn Tyr Val Arg Pro Ile Cys Leu Pro Gly Thr Asp 
            180                 185                 190         


Tyr Val Leu Lys Asp His Ser Arg Cys Thr Val Thr Gly Trp Gly Leu 
        195                 200                 205             


Ser Lys Ala Asp Gly Met Trp Pro Gln Phe Arg Thr Ile Gln Glu Lys 
    210                 215                 220                 


Glu Val Ile Ile Leu Asn Asn Lys Glu Cys Asp Asn Phe Tyr His Asn 
225                 230                 235                 240 


Phe Thr Lys Ile Pro Thr Leu Val Gln Ile Ile Lys Ser Gln Met Met 
                245                 250                 255     


Cys Ala Glu Asp Thr His Arg Glu Lys Phe Cys Tyr Glu Leu Thr Gly 
            260                 265                 270         


Glu Pro Leu Val Cys Ser Met Glu Gly Thr Trp Tyr Leu Val Gly Leu 
        275                 280                 285             


Val Ser Trp Gly Ala Gly Cys Gln Lys Ser Glu Ala Pro Pro Ile Tyr 
    290                 295                 300                 


Leu Gln Val Ser Ser Tyr Gln His Trp Ile Trp Asp Cys Leu Asn Gly 
305                 310                 315                 320 


Gln Ala Leu Ala Leu Pro Ala Pro Ser Arg Thr Leu Leu Leu Ala Leu 
                325                 330                 335     


Pro Leu Pro Leu Ser Leu Leu Ala Ala Leu 
            340                 345     


<210>  3025
<211>  308
<212>  PRT
<213>  Homo Sapiens

<400>  3025

Ser Ser Asn Asn Phe Asn Tyr Gly Ala Tyr His Ser Leu Glu Ala Ile 
1               5                   10                  15      


Tyr His Glu Met Asp Asn Ile Ala Ala Asp Phe Pro Asp Leu Ala Arg 
            20                  25                  30          


Arg Val Lys Ile Gly His Ser Phe Glu Asn Arg Pro Met Tyr Val Leu 
        35                  40                  45              


Lys Phe Ser Thr Gly Lys Gly Val Arg Arg Pro Ala Val Trp Leu Asn 
    50                  55                  60                  


Ala Gly Ile His Ser Arg Glu Trp Ile Ser Gln Ala Thr Ala Ile Trp 
65                  70                  75                  80  


Thr Ala Arg Lys Ile Val Ser Asp Tyr Gln Arg Asp Pro Ala Ile Thr 
                85                  90                  95      


Ser Ile Leu Glu Lys Met Asp Ile Phe Leu Leu Pro Val Ala Asn Pro 
            100                 105                 110         


Asp Gly Tyr Val Tyr Thr Gln Thr Gln Asn Arg Leu Trp Arg Lys Thr 
        115                 120                 125             


Arg Ser Arg Asn Pro Gly Ser Ser Cys Ile Gly Ala Asp Pro Asn Arg 
    130                 135                 140                 


Asn Trp Asn Ala Ser Phe Ala Gly Lys Gly Ala Ser Asp Asn Pro Cys 
145                 150                 155                 160 


Ser Glu Val Tyr His Gly Pro His Ala Asn Ser Glu Val Glu Val Lys 
                165                 170                 175     


Ser Val Val Asp Phe Ile Gln Lys His Gly Asn Phe Lys Gly Phe Ile 
            180                 185                 190         


Asp Leu His Ser Tyr Ser Gln Leu Leu Met Tyr Pro Tyr Gly Tyr Ser 
        195                 200                 205             


Val Lys Lys Ala Pro Asp Ala Glu Glu Leu Asp Lys Val Ala Arg Leu 
    210                 215                 220                 


Ala Ala Lys Ala Leu Ala Ser Val Ser Gly Thr Glu Tyr Gln Val Gly 
225                 230                 235                 240 


Pro Thr Cys Thr Thr Val Tyr Pro Ala Ser Gly Ser Ser Ile Asp Trp 
                245                 250                 255     


Ala Tyr Asp Asn Gly Ile Lys Phe Ala Phe Thr Phe Glu Leu Arg Asp 
            260                 265                 270         


Thr Gly Thr Tyr Gly Phe Leu Leu Pro Ala Asn Gln Ile Ile Pro Thr 
        275                 280                 285             


Ala Glu Glu Thr Trp Leu Gly Leu Lys Thr Ile Met Glu His Val Arg 
    290                 295                 300                 


Asp Asn Leu Tyr 
305             


<210>  3026
<211>  101
<212>  PRT
<213>  Homo Sapiens

<400>  3026

Leu Phe Leu Gly Cys Asp Thr Gly Pro Val Ala Gly Val Thr Val Pro 
1               5                   10                  15      


Tyr Gly Asn Ser Thr Ala Pro Gly Ser Ala Leu Asp Pro Tyr Ser Pro 
            20                  25                  30          


Cys Asn Asn Asn Cys Glu Cys Gln Thr Asp Ser Phe Thr Pro Val Cys 
        35                  40                  45              


Gly Ala Asp Gly Ile Thr Tyr Leu Ser Ala Cys Phe Ala Gly Cys Asn 
    50                  55                  60                  


Ser Thr Asn Leu Thr Gly Cys Ala Cys Leu Thr Thr Val Pro Ala Glu 
65                  70                  75                  80  


Asn Ala Thr Val Val Pro Gly Lys Cys Pro Ser Pro Gly Cys Gln Glu 
                85                  90                  95      


Ala Phe Leu Thr Phe 
            100     


<210>  3027
<211>  535
<212>  PRT
<213>  Homo Sapiens

<400>  3027

Gln Ile Tyr Phe Gly Asp Pro Gln Ile Phe Gln Gln Gly Ala Val Val 
1               5                   10                  15      


Thr Asp Ala Ala Arg Cys Thr Ser Leu Gly Ile Glu Val Leu Ser Lys 
            20                  25                  30          


Gln Gly Ser Ser Val Asp Ala Ala Val Ala Val Ala Leu Cys Leu Gly 
        35                  40                  45              


Ile Val Ala Pro His Ser Ser Gly Leu Gly Gly Gly Gly Val Met Leu 
    50                  55                  60                  


Val His Val Ile Arg Arg Asn Glu Ser His Leu Ile Asp Phe Arg Glu 
65                  70                  75                  80  


Ser Ala Pro Gly Ala Leu Arg Glu Glu Thr Leu Gln Arg Ser Trp Glu 
                85                  90                  95      


Thr Lys Pro Gly Leu Leu Val Gly Val Pro Gly Met Val Lys Gly Leu 
            100                 105                 110         


His Glu Ala His Gln Leu Tyr Gly Arg Leu Pro Trp Ser Gln Val Leu 
        115                 120                 125             


Ala Phe Ala Ala Ala Val Ala Gln Asp Gly Phe Asn Val Thr His Asp 
    130                 135                 140                 


Leu Ala Arg Ala Leu Ala Glu Gln Leu Pro Pro Asn Met Ser Glu Arg 
145                 150                 155                 160 


Phe Arg Glu Thr Phe Leu Pro Ser Gly Arg Pro Pro Leu Pro Gly Ser 
                165                 170                 175     


Leu Leu His Arg Pro Asp Leu Ala Glu Val Leu Asp Val Leu Gly Thr 
            180                 185                 190         


Ser Gly Pro Ala Ala Phe Tyr Ala Gly Gly Asn Leu Thr Leu Glu Met 
        195                 200                 205             


Val Ala Glu Ala Gln His Ala Gly Gly Val Ile Thr Glu Glu Asp Phe 
    210                 215                 220                 


Ser Asn Tyr Ser Ala Leu Val Glu Lys Pro Val Cys Gly Val Tyr Arg 
225                 230                 235                 240 


Gly His Leu Val Leu Ser Pro Pro Pro Pro His Thr Gly Pro Ala Leu 
                245                 250                 255     


Ile Ser Ala Leu Asn Ile Leu Glu Gly Phe Asn Leu Thr Ser Leu Val 
            260                 265                 270         


Ser Arg Glu Gln Ala Leu His Trp Val Ala Glu Thr Leu Lys Ile Ala 
        275                 280                 285             


Leu Ala Leu Ala Ser Arg Leu Gly Asp Pro Val Tyr Asp Ser Thr Ile 
    290                 295                 300                 


Thr Glu Ser Met Asp Asp Met Leu Ser Lys Val Glu Ala Ala Tyr Leu 
305                 310                 315                 320 


Arg Gly His Ile Asn Asp Ser Gln Ala Ala Pro Ala Pro Leu Leu Pro 
                325                 330                 335     


Val Tyr Glu Leu Asp Gly Ala Pro Thr Ala Ala Gln Val Leu Ile Met 
            340                 345                 350         


Gly Pro Asp Asp Phe Ile Val Ala Met Val Ser Ser Leu Asn Gln Pro 
        355                 360                 365             


Phe Gly Ser Gly Leu Ile Thr Pro Ser Gly Ile Leu Leu Asn Ser Gln 
    370                 375                 380                 


Met Leu Asp Phe Ser Trp Pro Asn Arg Thr Ala Asn His Ser Ala Pro 
385                 390                 395                 400 


Ser Leu Glu Asn Ser Val Gln Pro Gly Lys Arg Pro Leu Ser Phe Leu 
                405                 410                 415     


Leu Pro Thr Val Val Arg Pro Ala Glu Gly Leu Cys Gly Thr Tyr Leu 
            420                 425                 430         


Ala Leu Gly Ala Asn Gly Ala Ala Arg Gly Leu Ser Gly Leu Thr Gln 
        435                 440                 445             


Val Leu Leu Asn Val Leu Thr Leu Asn Arg Asn Leu Ser Asp Ser Leu 
    450                 455                 460                 


Ala Arg Gly Arg Leu His Pro Asp Leu Gln Ser Asn Leu Leu Gln Val 
465                 470                 475                 480 


Asp Ser Glu Phe Thr Glu Glu Glu Ile Glu Phe Leu Glu Ala Arg Gly 
                485                 490                 495     


His His Val Glu Lys Val Asp Val Leu Ser Trp Val His Gly Ser Arg 
            500                 505                 510         


Arg Thr Asn Asn Phe Ile Ile Ala Val Lys Asp Pro Arg Ser Pro Asp 
        515                 520                 525             


Ala Ala Gly Ala Thr Ile Leu 
    530                 535 


<210>  3028
<211>  407
<212>  PRT
<213>  Homo Sapiens

<400>  3028

Pro Asp Gln Gln Lys Val Leu Leu Val Ser Phe Asp Gly Phe Arg Trp 
1               5                   10                  15      


Asp Tyr Leu Tyr Lys Val Pro Thr Pro His Phe His Tyr Ile Met Lys 
            20                  25                  30          


Tyr Gly Val His Val Lys Gln Val Thr Asn Val Phe Ile Thr Lys Thr 
        35                  40                  45              


Tyr Pro Asn His Tyr Thr Leu Val Thr Gly Leu Phe Ala Glu Asn His 
    50                  55                  60                  


Gly Ile Val Ala Asn Asp Met Phe Asp Pro Ile Arg Asn Lys Ser Phe 
65                  70                  75                  80  


Ser Leu Asp His Met Asn Ile Tyr Asp Ser Lys Phe Trp Glu Glu Ala 
                85                  90                  95      


Thr Pro Ile Trp Ile Thr Asn Gln Arg Ala Gly His Thr Ser Gly Ala 
            100                 105                 110         


Ala Met Trp Pro Gly Thr Asp Val Lys Ile His Lys Arg Phe Pro Thr 
        115                 120                 125             


His Tyr Met Pro Tyr Asn Glu Ser Val Ser Phe Glu Asp Arg Val Ala 
    130                 135                 140                 


Lys Ile Ile Glu Trp Phe Thr Ser Lys Glu Pro Ile Asn Leu Gly Leu 
145                 150                 155                 160 


Leu Tyr Trp Glu Asp Pro Asp Asp Met Gly His His Leu Gly Pro Asp 
                165                 170                 175     


Ser Pro Leu Met Gly Pro Val Ile Ser Asp Ile Asp Lys Lys Leu Gly 
            180                 185                 190         


Tyr Leu Ile Gln Met Leu Lys Lys Ala Lys Leu Trp Asn Thr Leu Asn 
        195                 200                 205             


Leu Ile Ile Thr Ser Asp His Gly Met Thr Gln Cys Ser Glu Glu Arg 
    210                 215                 220                 


Leu Ile Glu Leu Asp Gln Tyr Leu Asp Lys Asp His Tyr Thr Leu Ile 
225                 230                 235                 240 


Asp Gln Ser Pro Val Ala Ala Ile Leu Pro Lys Glu Gly Lys Phe Asp 
                245                 250                 255     


Glu Val Tyr Glu Ala Leu Thr His Ala His Pro Asn Leu Thr Val Tyr 
            260                 265                 270         


Lys Lys Glu Asp Val Pro Glu Arg Trp His Tyr Lys Tyr Asn Ser Arg 
        275                 280                 285             


Ile Gln Pro Ile Ile Ala Val Ala Asp Glu Gly Trp His Ile Leu Gln 
    290                 295                 300                 


Asn Lys Ser Asp Asp Phe Leu Leu Gly Asn His Gly Tyr Asp Asn Ala 
305                 310                 315                 320 


Leu Ala Asp Met His Pro Ile Phe Leu Ala His Gly Pro Ala Phe Arg 
                325                 330                 335     


Lys Asn Phe Ser Lys Glu Ala Met Asn Ser Thr Asp Leu Tyr Pro Leu 
            340                 345                 350         


Leu Cys His Leu Leu Asn Ile Thr Ala Met Pro His Asn Gly Ser Phe 
        355                 360                 365             


Trp Asn Val Gln Asp Leu Leu Asn Ser Ala Met Pro Arg Val Val Pro 
    370                 375                 380                 


Tyr Thr Gln Ser Thr Ile Leu Leu Pro Gly Ser Val Lys Pro Ala Glu 
385                 390                 395                 400 


Tyr Asp Gln Glu Gly Ser Tyr 
                405         


<210>  3029
<211>  280
<212>  PRT
<213>  Homo Sapiens

<400>  3029

Ala Lys Met Lys Val Val Glu Glu Pro Asn Ala Phe Gly Val Asn Asn 
1               5                   10                  15      


Pro Phe Leu Pro Gln Ala Ser Arg Leu Gln Ala Lys Arg Asp Pro Ser 
            20                  25                  30          


Pro Val Ser Gly Pro Val His Leu Phe Arg Leu Ser Gly Lys Cys Phe 
        35                  40                  45              


Ser Leu Val Glu Ser Thr Tyr Lys Tyr Glu Phe Cys Pro Phe His Asn 
    50                  55                  60                  


Val Thr Gln His Glu Gln Thr Phe Arg Trp Asn Ala Tyr Ser Gly Ile 
65                  70                  75                  80  


Leu Gly Ile Trp His Glu Trp Glu Ile Ala Asn Asn Thr Phe Thr Gly 
                85                  90                  95      


Met Trp Met Arg Asp Gly Asp Ala Cys Arg Ser Arg Ser Arg Gln Ser 
            100                 105                 110         


Lys Val Glu Leu Ala Cys Gly Lys Ser Asn Arg Leu Ala His Val Ser 
        115                 120                 125             


Glu Pro Ser Thr Cys Val Tyr Ala Leu Thr Phe Glu Thr Pro Leu Val 
    130                 135                 140                 


Cys His Pro His Ala Leu Leu Val Tyr Pro Thr Leu Pro Glu Ala Leu 
145                 150                 155                 160 


Gln Arg Gln Trp Asp Gln Val Glu Gln Asp Leu Ala Asp Glu Leu Ile 
                165                 170                 175     


Thr Pro Gln Gly His Glu Lys Leu Leu Arg Thr Leu Phe Glu Asp Ala 
            180                 185                 190         


Gly Tyr Leu Lys Thr Pro Glu Asn Glu Pro Thr Gln Leu Glu Gly Gly 
        195                 200                 205             


Pro Asp Ser Leu Gly Phe Glu Thr Leu Glu Asn Cys Arg Lys Ala His 
    210                 215                 220                 


Lys Glu Leu Ser Lys Glu Ile Lys Arg Leu Lys Gly Leu Leu Thr Gln 
225                 230                 235                 240 


His Gly Ile Pro Tyr Thr Arg Pro Thr Glu Thr Ser Asn Leu Glu His 
                245                 250                 255     


Leu Gly His Glu Thr Pro Arg Ala Lys Ser Pro Glu Gln Leu Arg Gly 
            260                 265                 270         


Asp Pro Gly Leu Arg Gly Ser Leu 
        275                 280 


<210>  3030
<211>  206
<212>  PRT
<213>  Homo Sapiens

<400>  3030

Glu Gln Glu Val Glu Asn Leu Ser Gly Leu Ser Thr Asn Pro Glu Lys 
1               5                   10                  15      


Asp Ile Phe Val Val Arg Glu Asn Gly Thr Thr Cys Leu Met Ala Glu 
            20                  25                  30          


Phe Ala Ala Lys Phe Ile Val Pro Tyr Asp Val Trp Ala Ser Asn Tyr 
        35                  40                  45              


Val Asp Leu Ile Thr Glu Gln Ala Asp Ile Ala Leu Thr Arg Gly Ala 
    50                  55                  60                  


Glu Val Lys Gly Arg Cys Gly His Ser Gln Ser Glu Leu Gln Val Phe 
65                  70                  75                  80  


Trp Val Asp Arg Ala Tyr Ala Leu Lys Met Leu Phe Val Lys Glu Ser 
                85                  90                  95      


His Asn Met Ser Lys Gly Pro Glu Ala Thr Trp Arg Leu Ser Lys Val 
            100                 105                 110         


Gln Phe Val Tyr Asp Ser Ser Glu Lys Thr His Phe Lys Asp Ala Val 
        115                 120                 125             


Ser Ala Gly Lys His Thr Ala Asn Ser His His Leu Ser Ala Leu Val 
    130                 135                 140                 


Thr Pro Ala Gly Lys Ser Tyr Glu Cys Gln Ala Gln Gln Thr Ile Ser 
145                 150                 155                 160 


Leu Ala Ser Ser Asp Pro Gln Lys Thr Val Thr Met Ile Leu Ser Ala 
                165                 170                 175     


Val His Ile Gln Pro Phe Asp Ile Ile Ser Asp Phe Val Phe Ser Glu 
            180                 185                 190         


Glu His Lys Cys Pro Val Asp Glu Arg Glu Gln Leu Glu Glu 
        195                 200                 205     


<210>  3031
<211>  476
<212>  PRT
<213>  Homo Sapiens

<400>  3031

Met Trp Thr Gly Tyr Lys Ile Leu Ile Phe Ser Tyr Leu Thr Thr Glu 
1               5                   10                  15      


Ile Trp Met Glu Lys Arg Tyr Leu Ser Gln Arg Glu Val Asp Leu Glu 
            20                  25                  30          


Ala Tyr Phe Thr Arg Asn His Thr Val Leu Gln Gly Thr Arg Phe Lys 
        35                  40                  45              


Arg Ala Ile Phe Gln Gly Gln Tyr Cys Arg Asn Phe Gly Cys Cys Glu 
    50                  55                  60                  


Asp Arg Asp Asp Gly Cys Val Thr Glu Phe Tyr Ala Ala Asn Ala Leu 
65                  70                  75                  80  


Cys Tyr Cys Asp Lys Phe Cys Asp Arg Glu Asn Ser Asp Cys Cys Pro 
                85                  90                  95      


Asp Tyr Lys Ser Phe Cys Arg Glu Glu Lys Glu Trp Pro Pro His Thr 
            100                 105                 110         


Gln Pro Trp Tyr Pro Glu Gly Cys Phe Lys Asp Gly Gln His Tyr Glu 
        115                 120                 125             


Glu Gly Ser Val Ile Lys Glu Asn Cys Asn Ser Cys Thr Cys Ser Gly 
    130                 135                 140                 


Gln Gln Trp Lys Cys Ser Gln His Val Cys Leu Val Arg Ser Glu Leu 
145                 150                 155                 160 


Ile Glu Gln Val Asn Lys Gly Asp Tyr Gly Trp Thr Ala Gln Asn Tyr 
                165                 170                 175     


Ser Gln Phe Trp Gly Met Thr Leu Glu Asp Gly Phe Lys Phe Arg Leu 
            180                 185                 190         


Gly Thr Leu Pro Pro Ser Leu Met Leu Leu Ser Met Asn Glu Met Thr 
        195                 200                 205             


Ala Ser Leu Pro Ala Thr Thr Asp Leu Pro Glu Phe Phe Val Ala Ser 
    210                 215                 220                 


Tyr Lys Trp Pro Gly Trp Thr His Gly Pro Leu Asp Gln Lys Asn Cys 
225                 230                 235                 240 


Ala Ala Ser Trp Ala Phe Ser Thr Ala Ser Val Ala Ala Asp Arg Ile 
                245                 250                 255     


Ala Ile Gln Ser Lys Gly Arg Tyr Thr Ala Asn Leu Ser Pro Gln Asn 
            260                 265                 270         


Leu Ile Ser Cys Cys Ala Lys Asn Arg His Gly Cys Asn Ser Gly Ser 
        275                 280                 285             


Ile Asp Arg Ala Trp Trp Tyr Leu Arg Lys Arg Gly Leu Val Ser His 
    290                 295                 300                 


Ala Cys Tyr Pro Leu Phe Lys Asp Gln Asn Ala Thr Asn Asn Gly Cys 
305                 310                 315                 320 


Ala Met Ala Ser Arg Ser Asp Gly Arg Gly Lys Arg His Ala Thr Lys 
                325                 330                 335     


Pro Cys Pro Asn Asn Val Glu Lys Ser Asn Arg Ile Tyr Gln Cys Ser 
            340                 345                 350         


Pro Pro Tyr Arg Val Ser Ser Asn Glu Thr Glu Ile Met Lys Glu Ile 
        355                 360                 365             


Met Gln Asn Gly Pro Val Gln Ala Ile Met Gln Val His Glu Asp Phe 
    370                 375                 380                 


Phe His Tyr Lys Thr Gly Ile Tyr Arg His Val Thr Ser Thr Asn Lys 
385                 390                 395                 400 


Glu Ser Glu Lys Tyr Arg Lys Leu Gln Thr His Ala Val Lys Leu Thr 
                405                 410                 415     


Gly Trp Gly Thr Leu Arg Gly Ala Gln Gly Gln Lys Glu Lys Phe Trp 
            420                 425                 430         


Ile Ala Ala Asn Ser Trp Gly Lys Ser Trp Gly Glu Asn Gly Tyr Phe 
        435                 440                 445             


Arg Ile Leu Arg Gly Val Asn Glu Ser Asp Ile Glu Lys Leu Ile Ile 
    450                 455                 460                 


Ala Ala Trp Gly Gln Leu Thr Ser Ser Asp Glu Pro 
465                 470                 475     


<210>  3032
<211>  243
<212>  PRT
<213>  Homo Sapiens

<400>  3032

Ala Pro Ser Ala Arg Asp Pro Phe Ala Pro Gln Leu Gly Asp Thr Gln 
1               5                   10                  15      


Asn Cys Gln Leu Arg Cys Arg Asp Arg Asp Leu Gly Pro Gln Pro Ser 
            20                  25                  30          


Gln Ala Gly Leu Glu Gly Ala Ser Glu Ser Pro Tyr Asp Arg Ala Val 
        35                  40                  45              


Leu Ile Ser Ala Cys Glu Arg Gly Cys Arg Leu Phe Ser Ile Cys Arg 
    50                  55                  60                  


Phe Val Ala Arg Ser Ser Lys Pro Asn Ala Thr Gln Thr Glu Cys Glu 
65                  70                  75                  80  


Ala Ala Cys Val Glu Ala Tyr Val Lys Glu Ala Glu Gln Gln Ala Cys 
                85                  90                  95      


Ser His Gly Cys Trp Ser Gln Pro Ala Glu Pro Glu Pro Glu Gln Lys 
            100                 105                 110         


Arg Lys Val Leu Glu Ala Pro Ser Gly Ala Leu Ser Leu Leu Asp Leu 
        115                 120                 125             


Phe Ser Thr Leu Cys Asn Asp Leu Val Asn Ser Ala Gln Gly Phe Val 
    130                 135                 140                 


Ser Ser Thr Trp Thr Tyr Tyr Leu Gln Thr Asp Asn Gly Lys Val Val 
145                 150                 155                 160 


Val Phe Gln Thr Gln Pro Ile Val Glu Ser Leu Gly Phe Gln Gly Gly 
                165                 170                 175     


Arg Leu Gln Arg Val Glu Val Thr Trp Arg Gly Ser His Pro Glu Ala 
            180                 185                 190         


Leu Glu Val His Val Asp Pro Val Gly Pro Leu Asp Lys Val Arg Lys 
        195                 200                 205             


Ala Lys Ile Arg Val Lys Thr Ser Ser Lys Ala Lys Val Glu Ser Glu 
    210                 215                 220                 


Glu Pro Gln Asp Asn Asp Phe Leu Ser Cys Met Ser Arg Arg Ser Gly 
225                 230                 235                 240 


Leu Pro Arg 
            


<210>  3033
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  3033

Leu Ala Pro Ser Pro Gln Ser Pro Glu Thr Pro Ala Pro Gln Asn Gln 
1               5                   10                  15      


Thr Ser Arg Val Val Gln Ala Pro Lys Glu Glu Glu Glu Asp Glu Gln 
            20                  25                  30          


Glu Ala Ser Glu Glu Lys Ala Ser Glu Glu Glu Lys Ala Trp Leu Met 
        35                  40                  45              


Ala Ser Arg Gln Gln Leu Ala Lys Glu Thr Ser Asn Phe Gly Phe Ser 
    50                  55                  60                  


Leu Leu Arg Lys Ile Ser Met Arg His Asp Gly Asn Met Val Phe Ser 
65                  70                  75                  80  


Pro Phe Gly Met Ser Leu Ala Met Thr Gly Leu Met Leu Gly Ala Thr 
                85                  90                  95      


Gly Pro Thr Glu Thr Gln Ile Lys Arg Gly Leu His Leu Gln Ala Leu 
            100                 105                 110         


Lys Pro Thr Lys Pro Gly Leu Leu Pro Ser Leu Phe Lys Gly Leu Arg 
        115                 120                 125             


Glu Thr Leu Ser Arg Asn Leu Glu Leu Gly Leu Thr Gln Gly Ser Phe 
    130                 135                 140                 


Ala Phe Ile His Lys Asp Phe Asp Val Lys Glu Thr Phe Phe Asn Leu 
145                 150                 155                 160 


Ser Lys Arg Tyr Phe Asp Thr Glu Cys Val Pro Met Asn Phe Arg Asn 
                165                 170                 175     


Ala Ser Gln Ala Lys Arg Leu Met Asn His Tyr Ile Asn Lys Glu Thr 
            180                 185                 190         


Arg Gly Lys Ile Pro Lys Leu Phe Asp Glu Ile Asn Pro Glu Thr Lys 
        195                 200                 205             


Leu Ile Leu Val Asp Tyr Ile Leu Phe Lys Gly Lys Trp Leu Thr Pro 
    210                 215                 220                 


Phe Asp Pro Val Phe Thr Glu Val Asp Thr Phe His Leu Asp Lys Tyr 
225                 230                 235                 240 


Lys Thr Ile Lys Val Pro Met Met Tyr Gly Ala Gly Lys Phe Ala Ser 
                245                 250                 255     


Thr Phe Asp Lys Asn Phe Arg Cys His Val Leu Lys Leu Pro Tyr Gln 
            260                 265                 270         


Gly Asn Ala Thr Met Leu Val Val Leu Met Glu Lys Met Gly Asp His 
        275                 280                 285             


Leu Ala Leu Glu Asp Tyr Leu Thr Thr Asp Leu Val Glu Thr Trp Leu 
    290                 295                 300                 


Arg Asn Met Lys Thr Arg Asn Met Glu Val Phe Phe Pro Lys Phe Lys 
305                 310                 315                 320 


Leu Asp Gln Lys Tyr Glu Met His Glu Leu Leu Arg Gln Met Gly Ile 
                325                 330                 335     


Arg Arg Ile Phe Ser Pro Phe Ala Asp Leu Ser Glu Leu Ser Ala Thr 
            340                 345                 350         


Gly Arg Asn Leu Gln Val Ser Arg Val Leu Gln Arg Thr Val Ile Glu 
        355                 360                 365             


Val Asp Glu Arg Gly Thr Glu Ala Val Ala Gly Ile Leu Ser Glu Ile 
    370                 375                 380                 


Thr Ala Tyr Ser Met Pro Pro Val Ile Lys Val Asp Arg Pro Phe His 
385                 390                 395                 400 


Phe Met Ile Tyr Glu Glu Thr Ser Gly Met Leu Leu Phe Leu Gly Arg 
                405                 410                 415     


Val Val Asn Pro Thr Leu Leu 
            420             


<210>  3034
<211>  212
<212>  PRT
<213>  Homo Sapiens

<400>  3034

Ala Pro Ile His Asp Ala Asp Ala Gln Glu Ser Ser Leu Gly Leu Thr 
1               5                   10                  15      


Gly Leu Gln Ser Leu Leu Gln Gly Phe Ser Arg Leu Phe Leu Lys Gly 
            20                  25                  30          


Asn Leu Leu Arg Gly Ile Asp Ser Leu Phe Ser Ala Pro Met Asp Phe 
        35                  40                  45              


Arg Gly Leu Pro Gly Asn Tyr His Lys Glu Glu Asn Gln Glu His Gln 
    50                  55                  60                  


Leu Gly Asn Asn Thr Leu Ser Ser His Leu Gln Ile Asp Lys Met Thr 
65                  70                  75                  80  


Asp Asn Lys Thr Gly Glu Val Leu Ile Ser Glu Asn Val Val Ala Ser 
                85                  90                  95      


Ile Gln Pro Ala Glu Gly Ser Phe Glu Gly Asp Leu Lys Val Pro Arg 
            100                 105                 110         


Met Glu Glu Lys Glu Ala Leu Val Pro Ile Gln Lys Ala Thr Asp Ser 
        115                 120                 125             


Phe His Thr Glu Leu His Pro Arg Val Ala Phe Trp Ile Ile Lys Leu 
    130                 135                 140                 


Pro Arg Arg Arg Ser His Gln Asp Ala Leu Glu Gly Gly His Trp Leu 
145                 150                 155                 160 


Ser Glu Lys Arg His Arg Leu Gln Ala Ile Arg Asp Gly Leu Arg Lys 
                165                 170                 175     


Gly Thr His Lys Asp Val Leu Glu Glu Gly Thr Glu Ser Ser Ser His 
            180                 185                 190         


Ser Arg Leu Ser Pro Arg Lys Thr His Leu Leu Tyr Ile Leu Arg Pro 
        195                 200                 205             


Ser Arg Gln Leu 
    210         


<210>  3035
<211>  103
<212>  PRT
<213>  Homo Sapiens

<400>  3035

Val Leu Ala Gln Leu Asp Ala Leu Leu Val Phe Pro Gly Gln Val Ala 
1               5                   10                  15      


Gln Leu Ser Cys Thr Leu Ser Pro Gln His Val Thr Ile Arg Asp Tyr 
            20                  25                  30          


Gly Val Ser Trp Tyr Gln Gln Arg Ala Gly Ser Ala Pro Arg Tyr Leu 
        35                  40                  45              


Leu Tyr Tyr Arg Ser Glu Glu Asp His His Arg Pro Ala Asp Ile Pro 
    50                  55                  60                  


Asp Arg Phe Ser Ala Ala Lys Asp Glu Ala His Asn Ala Cys Val Leu 
65                  70                  75                  80  


Thr Ile Ser Pro Val Gln Pro Glu Asp Asp Ala Asp Tyr Tyr Cys Ser 
                85                  90                  95      


Val Gly Tyr Gly Phe Ser Pro 
            100             


<210>  3036
<211>  235
<212>  PRT
<213>  Homo Sapiens

<400>  3036

His Gly Trp Ala Asp Thr Arg Ala Ile Gly Ala Glu Glu Cys Arg Pro 
1               5                   10                  15      


Asn Ser Gln Pro Trp Gln Ala Gly Leu Phe His Leu Thr Arg Leu Phe 
            20                  25                  30          


Cys Gly Ala Thr Leu Ile Ser Asp Arg Trp Leu Leu Thr Ala Ala His 
        35                  40                  45              


Cys Arg Lys Pro Tyr Leu Trp Val Arg Leu Gly Glu His His Leu Trp 
    50                  55                  60                  


Lys Trp Glu Gly Pro Glu Gln Leu Phe Arg Val Thr Asp Phe Phe Pro 
65                  70                  75                  80  


His Pro Gly Phe Asn Lys Asp Leu Ser Ala Asn Asp His Asn Asp Asp 
                85                  90                  95      


Ile Met Leu Ile Arg Leu Pro Arg Gln Ala Arg Leu Ser Pro Ala Val 
            100                 105                 110         


Gln Pro Leu Asn Leu Ser Gln Thr Cys Val Ser Pro Gly Met Gln Cys 
        115                 120                 125             


Leu Ile Ser Gly Trp Gly Ala Val Ser Ser Pro Lys Ala Leu Phe Pro 
    130                 135                 140                 


Val Thr Leu Gln Cys Ala Asn Ile Ser Ile Leu Glu Asn Lys Leu Cys 
145                 150                 155                 160 


His Trp Ala Tyr Pro Gly His Ile Ser Asp Ser Met Leu Cys Ala Gly 
                165                 170                 175     


Leu Trp Glu Gly Gly Arg Gly Ser Cys Gln Gly Asp Ser Gly Gly Pro 
            180                 185                 190         


Leu Val Cys Asn Gly Thr Leu Ala Gly Val Val Ser Gly Gly Ala Glu 
        195                 200                 205             


Pro Cys Ser Arg Pro Arg Arg Pro Ala Val Tyr Thr Ser Val Cys His 
    210                 215                 220                 


Tyr Leu Asp Trp Ile Gln Glu Ile Met Glu Asn 
225                 230                 235 


<210>  3037
<211>  261
<212>  PRT
<213>  Homo Sapiens

<400>  3037

Gly Gly Val Ser Gln Glu Ser Ser Lys Val Leu Asn Thr Asn Gly Thr 
1               5                   10                  15      


Ser Gly Phe Leu Pro Gly Gly Tyr Thr Cys Phe Pro His Ser Gln Pro 
            20                  25                  30          


Trp Gln Ala Ala Leu Leu Val Gln Gly Arg Leu Leu Cys Gly Gly Val 
        35                  40                  45              


Leu Val His Pro Lys Trp Val Leu Thr Ala Ala His Cys Leu Lys Glu 
    50                  55                  60                  


Gly Leu Lys Val Tyr Leu Gly Lys His Ala Leu Gly Arg Val Glu Ala 
65                  70                  75                  80  


Gly Glu Gln Val Arg Glu Val Val His Ser Ile Pro His Pro Glu Tyr 
                85                  90                  95      


Arg Arg Ser Pro Thr His Leu Asn His Asp His Asp Ile Met Leu Leu 
            100                 105                 110         


Glu Leu Gln Ser Pro Val Gln Leu Thr Gly Tyr Ile Gln Thr Leu Pro 
        115                 120                 125             


Leu Ser His Asn Asn Arg Leu Thr Pro Gly Thr Thr Cys Arg Val Ser 
    130                 135                 140                 


Gly Trp Gly Thr Thr Thr Ser Pro Gln Val Asn Tyr Pro Lys Thr Leu 
145                 150                 155                 160 


Gln Cys Ala Asn Ile Gln Leu Arg Ser Asp Glu Glu Cys Arg Gln Val 
                165                 170                 175     


Tyr Pro Gly Lys Ile Thr Asp Asn Met Leu Cys Ala Gly Thr Lys Glu 
            180                 185                 190         


Gly Gly Lys Asp Ser Cys Glu Gly Asp Ser Gly Gly Pro Leu Val Cys 
        195                 200                 205             


Asn Arg Thr Leu Tyr Gly Ile Val Ser Trp Gly Asp Phe Pro Cys Gly 
    210                 215                 220                 


Gln Pro Asp Arg Pro Gly Val Tyr Thr Arg Val Ser Arg Tyr Val Leu 
225                 230                 235                 240 


Trp Ile Arg Glu Thr Ile Arg Lys Tyr Glu Thr Gln Gln Gln Lys Trp 
                245                 250                 255     


Leu Lys Gly Pro Gln 
            260     


<210>  3038
<211>  963
<212>  PRT
<213>  Homo Sapiens

<400>  3038

Ser Leu Arg Phe Asp Glu Cys Gly Ala Ser Ala Thr Pro Gly Ala Asp 
1               5                   10                  15      


Gly Gly Pro Ser Gly Phe Pro Glu Arg Gly Gly Asn Gly Ser Leu Pro 
            20                  25                  30          


Gly Ser Ala Arg Arg Asn His His Ala Gly Gly Asp Ser Trp Gln Pro 
        35                  40                  45              


Glu Ala Gly Gly Val Ala Ser Pro Gly Thr Thr Ser Ala Gln Pro Pro 
    50                  55                  60                  


Ser Glu Glu Glu Arg Glu Pro Trp Glu Pro Trp Thr Gln Leu Arg Leu 
65                  70                  75                  80  


Ser Gly His Leu Lys Pro Leu His Tyr Asn Leu Met Leu Thr Ala Phe 
                85                  90                  95      


Met Glu Asn Phe Thr Phe Ser Gly Glu Val Asn Val Glu Ile Ala Cys 
            100                 105                 110         


Arg Asn Ala Thr Arg Tyr Val Val Leu His Ala Ser Arg Val Ala Val 
        115                 120                 125             


Glu Lys Val Gln Leu Ala Glu Asp Arg Ala Phe Gly Ala Val Pro Val 
    130                 135                 140                 


Ala Gly Phe Phe Leu Tyr Pro Gln Thr Gln Val Leu Val Val Val Leu 
145                 150                 155                 160 


Asn Arg Thr Leu Asp Ala Gln Arg Asn Tyr Asn Leu Lys Ile Ile Tyr 
                165                 170                 175     


Asn Ala Leu Ile Glu Asn Glu Leu Leu Gly Phe Phe Arg Ser Ser Tyr 
            180                 185                 190         


Val Leu His Gly Glu Arg Arg Phe Leu Gly Val Thr Gln Phe Ser Pro 
        195                 200                 205             


Thr His Ala Arg Lys Ala Phe Pro Cys Phe Asp Glu Pro Ile Tyr Lys 
    210                 215                 220                 


Ala Thr Phe Lys Ile Ser Ile Lys His Gln Ala Thr Tyr Leu Ser Leu 
225                 230                 235                 240 


Ser Asn Met Pro Val Glu Thr Ser Val Phe Glu Glu Asp Gly Trp Val 
                245                 250                 255     


Thr Asp His Phe Ser Gln Thr Pro Leu Met Ser Thr Tyr Tyr Leu Ala 
            260                 265                 270         


Trp Ala Ile Cys Asn Phe Thr Tyr Arg Glu Thr Thr Thr Lys Ser Gly 
        275                 280                 285             


Val Val Val Arg Leu Tyr Ala Arg Pro Asp Ala Ile Arg Arg Gly Ser 
    290                 295                 300                 


Gly Asp Tyr Ala Leu His Ile Thr Lys Arg Leu Ile Glu Phe Tyr Glu 
305                 310                 315                 320 


Asp Tyr Phe Lys Val Pro Tyr Ser Leu Pro Lys Leu Asp Leu Leu Ala 
                325                 330                 335     


Val Pro Lys His Pro Tyr Ala Ala Met Glu Asn Trp Gly Leu Ser Ile 
            340                 345                 350         


Phe Val Glu Gln Arg Ile Leu Leu Asp Pro Ser Val Ser Ser Ile Ser 
        355                 360                 365             


Tyr Leu Leu Asp Val Thr Met Val Ile Val His Glu Ile Cys His Gln 
    370                 375                 380                 


Trp Phe Gly Asp Leu Val Thr Pro Val Trp Trp Glu Asp Val Trp Leu 
385                 390                 395                 400 


Lys Glu Gly Phe Ala His Tyr Phe Glu Phe Val Gly Thr Asp Tyr Leu 
                405                 410                 415     


Tyr Pro Gly Trp Asn Met Glu Lys Gln Arg Phe Leu Thr Asp Val Leu 
            420                 425                 430         


His Glu Val Met Leu Leu Asp Gly Leu Ala Ser Ser His Pro Val Ser 
        435                 440                 445             


Gln Glu Val Leu Gln Ala Thr Asp Ile Asp Arg Val Phe Asp Trp Ile 
    450                 455                 460                 


Ala Tyr Lys Lys Gly Ala Ala Leu Ile Arg Met Leu Ala Asn Phe Met 
465                 470                 475                 480 


Gly His Ser Val Phe Gln Arg Gly Leu Gln Asp Tyr Leu Thr Ile His 
                485                 490                 495     


Lys Tyr Gly Asn Ala Ala Arg Asn Asp Leu Trp Asn Thr Leu Ser Glu 
            500                 505                 510         


Ala Leu Lys Arg Asn Gly Lys Tyr Val Asn Ile Gln Glu Val Met Asp 
        515                 520                 525             


Gln Trp Thr Leu Gln Met Gly Tyr Pro Val Ile Thr Ile Leu Gly Asn 
    530                 535                 540                 


Thr Thr Ala Glu Asn Arg Ile Ile Ile Thr Gln Gln His Phe Ile Tyr 
545                 550                 555                 560 


Asp Ile Ser Ala Lys Thr Lys Ala Leu Lys Leu Gln Asn Asn Ser Tyr 
                565                 570                 575     


Leu Trp Gln Ile Pro Leu Thr Ile Val Val Gly Asn Arg Ser His Val 
            580                 585                 590         


Ser Ser Glu Ala Ile Ile Trp Val Ser Asn Lys Ser Glu His His Arg 
        595                 600                 605             


Ile Thr Tyr Leu Asp Lys Gly Ser Trp Leu Leu Gly Asn Ile Asn Gln 
    610                 615                 620                 


Thr Gly Tyr Phe Arg Val Asn Tyr Asp Leu Arg Asn Trp Arg Leu Leu 
625                 630                 635                 640 


Ile Asp Gln Leu Ile Arg Asn His Glu Val Leu Ser Val Ser Asn Arg 
                645                 650                 655     


Ala Gly Leu Ile Asp Asp Ala Phe Ser Leu Ala Arg Ala Gly Tyr Leu 
            660                 665                 670         


Pro Gln Asn Ile Pro Leu Glu Ile Ile Arg Tyr Leu Ser Glu Glu Lys 
        675                 680                 685             


Asp Phe Leu Pro Trp His Ala Ala Ser Arg Ala Leu Tyr Pro Leu Asp 
    690                 695                 700                 


Lys Leu Leu Asp Arg Met Glu Asn Tyr Asn Ile Phe Asn Glu Tyr Ile 
705                 710                 715                 720 


Leu Lys Gln Val Ala Thr Thr Tyr Ile Lys Leu Gly Trp Pro Lys Asn 
                725                 730                 735     


Asn Phe Asn Gly Ser Leu Val Gln Ala Ser Tyr Gln His Glu Glu Leu 
            740                 745                 750         


Arg Arg Glu Val Ile Met Leu Ala Cys Ser Phe Gly Asn Lys His Cys 
        755                 760                 765             


His Gln Gln Ala Ser Thr Leu Ile Ser Asp Trp Ile Ser Ser Asn Arg 
    770                 775                 780                 


Asn Arg Ile Pro Leu Asn Val Arg Asp Ile Val Tyr Cys Thr Gly Val 
785                 790                 795                 800 


Ser Leu Leu Asp Glu Asp Val Trp Glu Phe Ile Trp Met Lys Phe His 
                805                 810                 815     


Ser Thr Thr Ala Val Ser Glu Lys Lys Ile Leu Leu Glu Ala Leu Thr 
            820                 825                 830         


Cys Ser Asp Asp Arg Asn Leu Leu Asn Arg Leu Leu Asn Leu Ser Leu 
        835                 840                 845             


Asn Ser Glu Val Val Leu Asp Gln Asp Ala Ile Asp Val Ile Ile His 
    850                 855                 860                 


Val Ala Arg Asn Pro His Gly Arg Asp Leu Ala Trp Lys Phe Phe Arg 
865                 870                 875                 880 


Asp Lys Trp Lys Ile Leu Asn Thr Arg Tyr Gly Glu Ala Leu Phe Met 
                885                 890                 895     


Asn Ser Lys Leu Ile Ser Gly Val Thr Glu Phe Leu Asn Thr Glu Gly 
            900                 905                 910         


Glu Leu Lys Glu Leu Lys Asn Phe Met Lys Asn Tyr Asp Gly Val Ala 
        915                 920                 925             


Ala Ala Ser Phe Ser Arg Ala Val Glu Thr Val Glu Ala Asn Val Arg 
    930                 935                 940                 


Trp Lys Met Leu Tyr Gln Asp Glu Leu Phe Gln Trp Leu Gly Lys Ala 
945                 950                 955                 960 


Leu Arg His 
            


<210>  3039
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  3039

Thr Arg Gly Ile Lys His Arg Ile Lys Trp Asn Arg Lys Ala Leu Pro 
1               5                   10                  15      


Ser Thr Ala Gln Ile Thr Glu Ala Gln Val Ala Glu Asn Arg Pro Gly 
            20                  25                  30          


Ala Phe Ile Lys Gln Gly Arg Lys Leu Asp Ile Asp Phe Gly Ala Glu 
        35                  40                  45              


Gly Asn Arg Tyr Tyr Glu Ala Asn Tyr Trp Gln Phe Pro Asp Gly Ile 
    50                  55                  60                  


His Tyr Asn Gly Cys Ser Glu Ala Asn Val Thr Lys Glu Ala Phe Val 
65                  70                  75                  80  


Thr Gly Cys Ile Asn Ala Thr Gln Ala Ala Asn Gln Gly Glu Phe Gln 
                85                  90                  95      


Lys Pro Asp Asn Lys Leu His Gln Gln Val Leu Trp Arg Leu Val Gln 
            100                 105                 110         


Glu Leu Cys Ser Leu Lys His Cys Glu Phe Trp Leu Glu Arg Gly 
        115                 120                 125         


<210>  3040
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  3040

Gln Ser Pro Glu Arg Pro Val Phe Thr Cys Gly Gly Ile Leu Thr Gly 
1               5                   10                  15      


Glu Ser Gly Phe Ile Gly Ser Glu Gly Phe Pro Gly Val Tyr Pro Pro 
            20                  25                  30          


Asn Ser Lys Cys Thr Trp Lys Ile Thr Val Pro Glu Gly Lys Val Val 
        35                  40                  45              


Val Leu Asn Phe Arg Phe Ile Asp Leu Glu Ser Asp Asn Leu Cys Arg 
    50                  55                  60                  


Tyr Asp Phe Val Asp Val Tyr Asn Gly His Ala Asn Gly Gln Arg Ile 
65                  70                  75                  80  


Gly Arg Phe Cys Gly Thr Phe Arg Pro Gly Ala Leu Val Ser Ser Gly 
                85                  90                  95      


Asn Lys Met Met Val Gln Met Ile Ser Asp Ala Asn Thr Ala Gly Asn 
            100                 105                 110         


Gly Phe Met Ala Met Phe Ser Ala Ala Glu Pro Asn Glu Arg Gly Asp 
        115                 120                 125             


Gln Tyr Cys Gly Gly Leu Leu Asp Arg Pro Ser Gly Ser Phe Lys Thr 
    130                 135                 140                 


Pro Asn Trp Pro Asp Arg Asp Tyr Pro Ala Gly Val Thr Cys Val Trp 
145                 150                 155                 160 


His Ile Val Ala Pro Lys Asn Gln Leu Ile Glu Leu Lys Phe Glu Lys 
                165                 170                 175     


Phe Asp Val Glu Arg Asp Asn Tyr Cys Arg Tyr Asp Tyr Val Ala Val 
            180                 185                 190         


Phe Asn Gly Gly Glu Val Asn Asp Ala Arg Arg Ile Gly Lys Tyr Cys 
        195                 200                 205             


Gly Asp Ser Pro Pro Ala Pro Ile Val Ser Glu Arg Asn Glu Leu Leu 
    210                 215                 220                 


Ile Gln Phe Leu Ser Asp Leu Ser Leu Thr Ala Asp Gly Phe Ile Gly 
225                 230                 235                 240 


His Tyr Ile Phe Arg Pro Lys Lys Leu Pro Thr Thr Thr Glu Gln Pro 
                245                 250                 255     


Val Thr Thr Thr Phe Pro Val Thr Thr Gly Leu Lys Pro Thr Val Ala 
            260                 265                 270         


Leu Cys Gln Gln Lys Cys Arg Arg Thr Gly Thr Leu Glu Gly Asn Tyr 
        275                 280                 285             


Cys Ser Ser Asp Phe Val Leu Ala Gly Thr Val Ile Thr Thr Ile Thr 
    290                 295                 300                 


Arg Asp Gly Ser Leu His Ala Thr Val Ser Ile Ile Asn Ile Tyr Lys 
305                 310                 315                 320 


Glu Gly Asn Leu Ala Ile Gln Gln Ala Gly Lys Asn Met Ser Ala Arg 
                325                 330                 335     


Leu Thr Val Val Cys Lys Gln Cys Pro Leu Leu Arg Arg Gly Leu Asn 
            340                 345                 350         


Tyr Ile Ile Met Gly Gln Val Gly Glu Asp Gly Arg Gly Lys Ile Met 
        355                 360                 365             


Pro Asn Ser Phe Ile Met Met Phe Lys Thr Lys Asn Gln Lys Leu Leu 
    370                 375                 380                 


Asp Ala Leu Lys Asn Lys Gln Cys 
385                 390         


<210>  3041
<211>  880
<212>  PRT
<213>  Homo Sapiens

<400>  3041

Tyr Ile Thr Asp Glu Asn Pro Glu Val Met Ile Pro Phe Thr Asn Ala 
1               5                   10                  15      


Asn Tyr Asp Ser His Pro Met Leu Tyr Phe Ser Arg Ala Glu Val Ala 
            20                  25                  30          


Glu Leu Gln Leu Arg Ala Ala Ser Ser His Glu His Ile Ala Ala Arg 
        35                  40                  45              


Leu Thr Glu Ala Val His Thr Met Leu Ser Ser Pro Leu Glu Tyr Leu 
    50                  55                  60                  


Pro Pro Trp Asp Pro Lys Asp Tyr Ser Ala Arg Trp Asn Glu Ile Phe 
65                  70                  75                  80  


Gly Asn Asn Leu Gly Ala Leu Ala Met Phe Cys Val Leu Tyr Pro Glu 
                85                  90                  95      


Asn Ile Glu Ala Arg Asp Met Ala Lys Asp Tyr Met Glu Arg Met Ala 
            100                 105                 110         


Ala Gln Pro Ser Trp Leu Val Lys Asp Ala Pro Trp Asp Glu Val Pro 
        115                 120                 125             


Leu Ala His Ser Leu Val Gly Phe Ala Thr Ala Tyr Asp Phe Leu Tyr 
    130                 135                 140                 


Asn Tyr Leu Ser Lys Thr Gln Gln Glu Lys Phe Leu Glu Val Ile Ala 
145                 150                 155                 160 


Asn Ala Ser Gly Tyr Met Tyr Glu Thr Ser Tyr Arg Arg Gly Trp Gly 
                165                 170                 175     


Phe Gln Tyr Leu His Asn His Gln Pro Thr Asn Cys Met Ala Leu Leu 
            180                 185                 190         


Thr Gly Ser Leu Val Leu Met Asn Gln Gly Tyr Leu Gln Glu Ala Tyr 
        195                 200                 205             


Leu Trp Thr Lys Gln Val Leu Thr Ile Met Glu Lys Ser Leu Val Leu 
    210                 215                 220                 


Leu Arg Glu Val Thr Asp Gly Ser Leu Tyr Glu Gly Val Ala Tyr Gly 
225                 230                 235                 240 


Ser Tyr Thr Thr Arg Ser Leu Phe Gln Tyr Met Phe Leu Val Gln Arg 
                245                 250                 255     


His Phe Asn Ile Asn His Phe Gly His Pro Trp Leu Lys Gln His Phe 
            260                 265                 270         


Ala Phe Met Tyr Arg Thr Ile Leu Pro Gly Phe Gln Arg Thr Val Ala 
        275                 280                 285             


Ile Ala Asp Ser Asn Tyr Asn Trp Phe Tyr Gly Pro Glu Ser Gln Leu 
    290                 295                 300                 


Val Phe Leu Asp Lys Phe Val Met Arg Asn Gly Ser Gly Asn Trp Leu 
305                 310                 315                 320 


Ala Asp Gln Ile Arg Arg Asn Arg Val Val Glu Gly Pro Gly Thr Pro 
                325                 330                 335     


Ser Lys Gly Gln Arg Trp Cys Thr Leu His Thr Glu Phe Leu Trp Tyr 
            340                 345                 350         


Asp Gly Ser Leu Lys Ser Val Pro Pro Pro Asp Phe Gly Thr Pro Thr 
        355                 360                 365             


Leu His Tyr Phe Glu Asp Trp Gly Val Val Thr Tyr Gly Ser Ala Leu 
    370                 375                 380                 


Pro Ala Glu Ile Asn Arg Ser Phe Leu Ser Phe Lys Ser Gly Lys Leu 
385                 390                 395                 400 


Gly Gly Arg Ala Ile Tyr Asp Ile Val His Arg Asn Lys Tyr Lys Asp 
                405                 410                 415     


Trp Ile Lys Gly Trp Arg Asn Phe Asn Ala Gly His Glu His Pro Asp 
            420                 425                 430         


Gln Asn Ser Phe Thr Phe Ala Pro Asn Gly Val Pro Phe Ile Thr Glu 
        435                 440                 445             


Ala Leu Tyr Gly Pro Lys Tyr Thr Phe Phe Asn Asn Val Leu Met Phe 
    450                 455                 460                 


Ser Pro Ala Val Ser Lys Ser Cys Phe Ser Pro Trp Val Gly Gln Val 
465                 470                 475                 480 


Thr Glu Asp Cys Ser Ser Lys Trp Ser Lys Tyr Lys His Asp Leu Ala 
                485                 490                 495     


Ala Ser Cys Gln Gly Arg Val Val Ala Ala Glu Glu Lys Asn Gly Val 
            500                 505                 510         


Val Phe Ile Arg Gly Glu Gly Val Gly Ala Tyr Asn Pro Gln Leu Asn 
        515                 520                 525             


Leu Lys Asn Val Gln Arg Asn Leu Ile Leu Leu His Pro Gln Leu Leu 
    530                 535                 540                 


Leu Leu Val Asp Gln Ile His Leu Gly Glu Glu Ser Pro Leu Glu Thr 
545                 550                 555                 560 


Ala Ala Ser Phe Phe His Asn Val Asp Val Pro Phe Glu Glu Thr Val 
                565                 570                 575     


Val Asp Gly Val His Gly Ala Phe Ile Arg Gln Arg Asp Gly Leu Tyr 
            580                 585                 590         


Lys Met Tyr Trp Met Asp Asp Thr Gly Tyr Ser Glu Lys Ala Thr Phe 
        595                 600                 605             


Ala Ser Val Thr Tyr Pro Arg Gly Tyr Pro Tyr Asn Gly Thr Asn Tyr 
    610                 615                 620                 


Val Asn Val Thr Met His Leu Arg Ser Pro Ile Thr Arg Ala Ala Tyr 
625                 630                 635                 640 


Leu Phe Ile Gly Pro Ser Ile Asp Val Gln Ser Phe Thr Val His Gly 
                645                 650                 655     


Asp Ser Gln Gln Leu Asp Val Phe Ile Ala Thr Ser Lys His Ala Tyr 
            660                 665                 670         


Ala Thr Tyr Leu Trp Thr Gly Glu Ala Thr Gly Gln Ser Ala Phe Ala 
        675                 680                 685             


Gln Val Ile Ala Asp Arg His Lys Ile Leu Phe Asp Arg Asn Ser Ala 
    690                 695                 700                 


Ile Lys Ser Ser Ile Val Pro Glu Val Lys Asp Tyr Ala Ala Ile Val 
705                 710                 715                 720 


Glu Gln Asn Leu Gln His Phe Lys Pro Val Phe Gln Leu Leu Glu Lys 
                725                 730                 735     


Gln Ile Leu Ser Arg Val Arg Asn Thr Ala Ser Phe Arg Lys Thr Ala 
            740                 745                 750         


Glu Arg Leu Leu Arg Phe Ser Asp Lys Arg Gln Thr Glu Glu Ala Ile 
        755                 760                 765             


Asp Arg Ile Phe Ala Ile Ser Gln Gln Gln Gln Gln Gln Ser Lys Ser 
    770                 775                 780                 


Lys Lys Asn Arg Arg Ala Gly Lys Arg Tyr Lys Phe Val Asp Ala Val 
785                 790                 795                 800 


Pro Asp Ile Phe Ala Gln Ile Glu Val Asn Glu Lys Lys Ile Arg Gln 
                805                 810                 815     


Lys Ala Gln Ile Leu Ala Gln Lys Glu Leu Pro Ile Asp Glu Asp Glu 
            820                 825                 830         


Glu Met Lys Asp Leu Leu Asp Phe Ala Asp Val Thr Tyr Glu Lys His 
        835                 840                 845             


Lys Asn Gly Gly Leu Ile Lys Gly Arg Phe Gly Gln Ala Arg Met Val 
    850                 855                 860                 


Thr Thr Thr His Ser Arg Ala Pro Ser Leu Ser Ala Ser Tyr Thr Arg 
865                 870                 875                 880 


<210>  3042
<211>  383
<212>  PRT
<213>  Homo Sapiens

<400>  3042

His Tyr Val Arg Tyr Asn Gln Lys Lys Thr Tyr Asn Tyr Tyr Ser Thr 
1               5                   10                  15      


Leu Ser Phe Thr Thr Asp Lys Leu Tyr Ala Glu Phe Gly Arg Glu Ala 
            20                  25                  30          


Ser Asn Asn Phe Thr Glu Met Ser Gln Arg Leu Glu Ser Met Val Lys 
        35                  40                  45              


Asn Ala Phe Tyr Lys Ser Pro Leu Arg Glu Glu Phe Val Lys Ser Gln 
    50                  55                  60                  


Val Ile Lys Phe Ser Gln Gln Lys His Gly Val Leu Ala His Met Leu 
65                  70                  75                  80  


Leu Ile Cys Arg Phe His Ser Thr Glu Asp Pro Glu Thr Val Asp Lys 
                85                  90                  95      


Ile Val Gln Leu Val Leu His Glu Lys Leu Gln Asp Ala Val Gly Pro 
            100                 105                 110         


Pro Lys Val Asp Pro His Ser Val Lys Ile Lys Lys Ile Asn Lys Thr 
        115                 120                 125             


Glu Thr Asp Ser Tyr Leu Asn His Cys Cys Gly Thr Arg Arg Ser Lys 
    130                 135                 140                 


Thr Leu Gly Gln Ser Leu Arg Ile Val Gly Gly Thr Glu Val Glu Glu 
145                 150                 155                 160 


Gly Glu Trp Pro Trp Gln Ala Ser Leu Gln Trp Asp Gly Ser His Arg 
                165                 170                 175     


Cys Gly Ala Thr Leu Ile Asn Ala Thr Trp Leu Val Ser Ala Ala His 
            180                 185                 190         


Cys Phe Thr Thr Tyr Lys Asn Pro Ala Arg Trp Thr Ala Ser Phe Gly 
        195                 200                 205             


Val Thr Ile Lys Pro Ser Lys Met Lys Arg Gly Leu Arg Arg Ile Ile 
    210                 215                 220                 


Val His Glu Lys Tyr Lys His Pro Ser His Asp Tyr Asp Ile Ser Leu 
225                 230                 235                 240 


Ala Glu Leu Ser Ser Pro Val Pro Tyr Thr Asn Ala Val His Arg Val 
                245                 250                 255     


Cys Leu Pro Asp Ala Ser Tyr Glu Phe Gln Pro Gly Asp Val Met Phe 
            260                 265                 270         


Val Thr Gly Phe Gly Ala Leu Lys Asn Asp Gly Tyr Ser Gln Asn His 
        275                 280                 285             


Leu Arg Gln Ala Gln Val Thr Leu Ile Asp Ala Thr Thr Cys Asn Glu 
    290                 295                 300                 


Pro Gln Ala Tyr Asn Asp Ala Ile Thr Pro Arg Met Leu Cys Ala Gly 
305                 310                 315                 320 


Ser Leu Glu Gly Lys Thr Asp Ala Cys Gln Gly Asp Ser Gly Gly Pro 
                325                 330                 335     


Leu Val Ser Ser Asp Ala Arg Asp Ile Trp Tyr Leu Ala Gly Ile Val 
            340                 345                 350         


Ser Trp Gly Asp Glu Cys Ala Lys Pro Asn Lys Pro Gly Val Tyr Thr 
        355                 360                 365             


Arg Val Thr Ala Leu Arg Asp Trp Ile Thr Ser Lys Thr Gly Ile 
    370                 375                 380             


<210>  3043
<211>  70
<212>  PRT
<213>  Homo Sapiens

<400>  3043

Gly Leu Asn Gln Leu Tyr Phe Tyr Tyr Glu Thr Arg Ala Ile Asp Glu 
1               5                   10                  15      


Pro Asn Asn Cys Lys Gly Ile Arg Cys Glu Lys Gln Asn Asn Ala Phe 
            20                  25                  30          


Ser Thr Leu Phe Glu Thr Leu Gln Ser Leu Phe Trp Ser Val Phe Gly 
        35                  40                  45              


Leu Leu Asn Leu Tyr Val Thr Asn Val Lys Ala Arg His Glu Phe Thr 
    50                  55                  60                  


Glu Phe Val Gly Ala Thr 
65                  70  


<210>  3044
<211>  186
<212>  PRT
<213>  Homo Sapiens

<400>  3044

Phe Gly Asp Glu Glu Glu Arg Arg Cys Asp Pro Ile Arg Ile Ser Met 
1               5                   10                  15      


Cys Gln Asn Leu Gly Tyr Asn Val Thr Lys Met Pro Asn Leu Val Gly 
            20                  25                  30          


His Glu Leu Gln Thr Asp Ala Glu Leu Gln Leu Thr Thr Phe Thr Pro 
        35                  40                  45              


Leu Ile Gln Tyr Gly Cys Ser Ser Gln Leu Gln Phe Phe Leu Cys Ser 
    50                  55                  60                  


Val Tyr Val Pro Met Cys Thr Glu Lys Ile Asn Ile Pro Ile Gly Pro 
65                  70                  75                  80  


Cys Gly Gly Met Cys Leu Ser Val Lys Arg Arg Cys Glu Pro Val Leu 
                85                  90                  95      


Lys Glu Phe Gly Phe Ala Trp Pro Glu Ser Leu Asn Cys Ser Lys Phe 
            100                 105                 110         


Pro Pro Gln Asn Asp His Asn His Met Cys Met Glu Gly Pro Gly Asp 
        115                 120                 125             


Glu Glu Val Pro Leu Pro His Lys Thr Pro Ile Gln Pro Gly Glu Glu 
    130                 135                 140                 


Cys His Ser Val Gly Thr Asn Ser Asp Gln Tyr Ile Trp Val Lys Arg 
145                 150                 155                 160 


Ser Leu Asn Cys Val Leu Lys Cys Gly Tyr Asp Ala Gly Leu Tyr Ser 
                165                 170                 175     


Arg Ser Ala Lys Glu Phe Thr Asp Ile Trp 
            180                 185     


<210>  3045
<211>  205
<212>  PRT
<213>  Homo Sapiens

<400>  3045

Ile Ser Ser Met Asp Met Glu Arg Pro Gly Asp Gly Lys Cys Gln Pro 
1               5                   10                  15      


Ile Glu Ile Pro Met Cys Lys Asp Ile Gly Tyr Asn Met Thr Arg Met 
            20                  25                  30          


Pro Asn Leu Met Gly His Glu Asn Gln Arg Glu Ala Ala Ile Gln Leu 
        35                  40                  45              


His Glu Phe Ala Pro Leu Val Glu Tyr Gly Cys His Gly His Leu Arg 
    50                  55                  60                  


Phe Phe Leu Cys Ser Leu Tyr Ala Pro Met Cys Thr Glu Gln Val Ser 
65                  70                  75                  80  


Thr Pro Ile Pro Ala Cys Arg Val Met Cys Glu Gln Ala Arg Leu Lys 
                85                  90                  95      


Cys Ser Pro Ile Met Glu Gln Phe Asn Phe Lys Trp Pro Asp Ser Leu 
            100                 105                 110         


Asp Cys Arg Lys Leu Pro Asn Lys Asn Asp Pro Asn Tyr Leu Cys Met 
        115                 120                 125             


Glu Ala Pro Asn Asn Gly Ser Asp Glu Pro Thr Arg Gly Ser Gly Leu 
    130                 135                 140                 


Phe Pro Pro Leu Phe Arg Pro Gln Arg Pro His Ser Ala Gln Glu His 
145                 150                 155                 160 


Pro Leu Lys Asp Gly Gly Pro Gly Arg Gly Gly Cys Asp Asn Pro Gly 
                165                 170                 175     


Lys Phe His His Val Glu Lys Ser Ala Ser Cys Ala Pro Leu Cys Thr 
            180                 185                 190         


Pro Gly Val Asp Val Tyr Trp Ser Arg Glu Asp Lys Arg 
        195                 200                 205 


<210>  3046
<211>  275
<212>  PRT
<213>  Homo Sapiens

<400>  3046

Ala Asp Gly Gly Gln His Trp Thr Tyr Glu Gly Pro His Gly Gln Asp 
1               5                   10                  15      


His Trp Pro Ala Ser Tyr Pro Glu Cys Gly Asn Asn Ala Gln Ser Pro 
            20                  25                  30          


Ile Asp Ile Gln Thr Asp Ser Val Thr Phe Asp Pro Asp Leu Pro Ala 
        35                  40                  45              


Leu Gln Pro His Gly Tyr Asp Gln Pro Gly Thr Glu Pro Leu Asp Leu 
    50                  55                  60                  


His Asn Asn Gly His Thr Val Gln Leu Ser Leu Pro Ser Thr Leu Tyr 
65                  70                  75                  80  


Leu Gly Gly Leu Pro Arg Lys Tyr Val Ala Ala Gln Leu His Leu His 
                85                  90                  95      


Trp Gly Gln Lys Gly Ser Pro Gly Gly Ser Glu His Gln Ile Asn Ser 
            100                 105                 110         


Glu Ala Thr Phe Ala Glu Leu His Ile Val His Tyr Asp Ser Asp Ser 
        115                 120                 125             


Tyr Asp Ser Leu Ser Glu Ala Ala Glu Arg Pro Gln Gly Leu Ala Val 
    130                 135                 140                 


Leu Gly Ile Leu Ile Glu Val Gly Glu Thr Lys Asn Ile Ala Tyr Glu 
145                 150                 155                 160 


His Ile Leu Ser His Leu His Glu Val Arg His Lys Asp Gln Lys Thr 
                165                 170                 175     


Ser Val Pro Pro Phe Asn Leu Arg Glu Leu Leu Pro Lys Gln Leu Gly 
            180                 185                 190         


Gln Tyr Phe Arg Tyr Asn Gly Ser Leu Thr Thr Pro Pro Cys Tyr Gln 
        195                 200                 205             


Ser Val Leu Trp Thr Val Phe Tyr Arg Arg Ser Gln Ile Ser Met Glu 
    210                 215                 220                 


Gln Leu Glu Lys Leu Gln Gly Thr Leu Phe Ser Thr Glu Glu Glu Pro 
225                 230                 235                 240 


Ser Lys Leu Leu Val Gln Asn Tyr Arg Ala Leu Gln Pro Leu Asn Gln 
                245                 250                 255     


Arg Met Val Phe Ala Ser Phe Ile Gln Ala Gly Ser Ser Tyr Thr Thr 
            260                 265                 270         


Gly Glu Met 
        275 


<210>  3047
<211>  187
<212>  PRT
<213>  Homo Sapiens

<400>  3047

Ala Pro Arg Pro Cys Gln Ala Pro Gln Gln Trp Glu Gly Arg Gln Val 
1               5                   10                  15      


Met Tyr Gln Gln Ser Ser Gly Arg Asn Ser Arg Ala Leu Leu Ser Tyr 
            20                  25                  30          


Asp Gly Leu Asn Gln Arg Val Arg Val Leu Asp Glu Arg Lys Ala Leu 
        35                  40                  45              


Ile Pro Cys Lys Arg Leu Phe Glu Tyr Ile Leu Leu Tyr Lys Asp Gly 
    50                  55                  60                  


Val Met Phe Gln Ile Asp Gln Ala Thr Lys Gln Cys Ser Lys Met Thr 
65                  70                  75                  80  


Leu Thr Gln Pro Trp Asp Pro Leu Asp Ile Pro Gln Asn Ser Thr Phe 
                85                  90                  95      


Glu Asp Gln Tyr Ser Ile Gly Gly Pro Gln Glu Gln Ile Thr Val Gln 
            100                 105                 110         


Glu Trp Ser Asp Arg Lys Ser Ala Arg Ser Tyr Glu Thr Trp Ile Gly 
        115                 120                 125             


Ile Tyr Thr Val Lys Asp Cys Tyr Pro Val Gln Glu Thr Phe Thr Ile 
    130                 135                 140                 


Asn Tyr Ser Val Ile Leu Ser Thr Arg Phe Phe Asp Ile Gln Leu Gly 
145                 150                 155                 160 


Ile Lys Asp Pro Ser Val Phe Thr Pro Pro Ser Thr Cys Gln Met Ala 
                165                 170                 175     


Gln Leu Glu Lys Met Ser Glu Asp Cys Ser Trp 
            180                 185         


<210>  3048
<211>  275
<212>  PRT
<213>  Homo Sapiens

<400>  3048

Ala Pro Ala Pro His Arg Ala Ser Tyr Lys Pro Val Ile Val Val His 
1               5                   10                  15      


Gly Leu Phe Asp Ser Ser Tyr Ser Phe Arg His Leu Leu Glu Tyr Ile 
            20                  25                  30          


Asn Glu Thr His Pro Gly Thr Val Val Thr Val Leu Asp Leu Phe Asp 
        35                  40                  45              


Gly Arg Glu Ser Leu Arg Pro Leu Trp Glu Gln Val Gln Gly Phe Arg 
    50                  55                  60                  


Glu Ala Val Val Pro Ile Met Ala Lys Ala Pro Gln Gly Val His Leu 
65                  70                  75                  80  


Ile Cys Tyr Ser Gln Gly Gly Leu Val Cys Arg Ala Leu Leu Ser Val 
                85                  90                  95      


Met Asp Asp His Asn Val Asp Ser Phe Ile Ser Leu Ser Ser Pro Gln 
            100                 105                 110         


Met Gly Gln Tyr Gly Asp Thr Asp Tyr Leu Lys Trp Leu Phe Pro Thr 
        115                 120                 125             


Ser Met Arg Ser Asn Leu Tyr Arg Ile Cys Tyr Ser Pro Trp Gly Gln 
    130                 135                 140                 


Glu Phe Ser Ile Cys Asn Tyr Trp His Asp Pro His His Asp Asp Leu 
145                 150                 155                 160 


Tyr Leu Asn Ala Ser Ser Phe Leu Ala Leu Ile Asn Gly Glu Arg Asp 
                165                 170                 175     


His Pro Asn Ala Thr Val Trp Arg Lys Asn Phe Leu Arg Val Gly His 
            180                 185                 190         


Leu Val Leu Ile Gly Gly Pro Asp Asp Gly Val Ile Thr Pro Trp Gln 
        195                 200                 205             


Ser Ser Phe Phe Gly Phe Tyr Asp Ala Asn Glu Thr Val Leu Glu Met 
    210                 215                 220                 


Glu Glu Gln Leu Val Tyr Leu Arg Asp Ser Phe Gly Leu Lys Thr Leu 
225                 230                 235                 240 


Leu Ala Arg Gly Ala Ile Val Arg Cys Pro Met Ala Gly Ile Ser His 
                245                 250                 255     


Thr Ala Trp His Ser Asn Arg Thr Leu Tyr Glu Thr Cys Ile Glu Pro 
            260                 265                 270         


Trp Leu Ser 
        275 


<210>  3049
<211>  141
<212>  PRT
<213>  Homo Sapiens

<400>  3049

Gly Gln Thr Pro Arg Pro Ala Glu Arg Gly Pro Pro Val Arg Leu Phe 
1               5                   10                  15      


Thr Glu Glu Glu Leu Ala Arg Tyr Gly Gly Glu Glu Glu Asp Gln Pro 
            20                  25                  30          


Ile Tyr Leu Ala Val Lys Gly Val Val Phe Asp Val Thr Ser Gly Lys 
        35                  40                  45              


Glu Phe Tyr Gly Arg Gly Ala Pro Tyr Asn Ala Leu Thr Gly Lys Asp 
    50                  55                  60                  


Ser Thr Arg Gly Val Ala Lys Met Ser Leu Asp Pro Ala Asp Leu Thr 
65                  70                  75                  80  


His Asp Thr Thr Gly Leu Thr Ala Lys Glu Leu Glu Ala Leu Asp Glu 
                85                  90                  95      


Val Phe Thr Lys Val Tyr Lys Ala Lys Tyr Pro Ile Val Gly Tyr Thr 
            100                 105                 110         


Ala Arg Arg Ile Leu Asn Glu Asp Gly Ser Pro Asn Leu Asp Phe Lys 
        115                 120                 125             


Pro Glu Asp Gln Pro His Phe Asp Ile Lys Asp Glu Phe 
    130                 135                 140     


<210>  3050
<211>  104
<212>  PRT
<213>  Homo Sapiens

<400>  3050

Tyr Tyr Asn Val Ile Ile Ala Tyr Ser Leu Tyr Tyr Met Phe Ala Ser 
1               5                   10                  15      


Phe Gln Ser Glu Leu Pro Trp Lys Asn Cys Ser Ser Trp Ser Asp Lys 
            20                  25                  30          


Asn Cys Ser Arg Ser Pro Ile Val Thr His Cys Asn Val Ser Thr Val 
        35                  40                  45              


Asn Lys Gly Ile Gln Glu Ile Ile Gln Met Asn Lys Ser Trp Val Asp 
    50                  55                  60                  


Ile Asn Asn Phe Thr Cys Ile Asn Gly Ser Glu Ile Tyr Gln Pro Gly 
65                  70                  75                  80  


Gln Leu Pro Ser Glu Gln Tyr Trp Asn Lys Val Ala Leu Gln Arg Ser 
                85                  90                  95      


Ser Gly Met Asn Glu Thr Gly Val 
            100                 


<210>  3051
<211>  247
<212>  PRT
<213>  Homo Sapiens

<400>  3051

Glu Gly Asn Tyr Pro Ser Pro Ile Pro Lys Phe His Phe Glu Phe Ser 
1               5                   10                  15      


Ser Ala Val Pro Glu Val Val Leu Asn Leu Phe Asn Cys Lys Asn Cys 
            20                  25                  30          


Ala Asn Glu Ala Val Val Gln Lys Ile Leu Asp Arg Val Leu Ser Arg 
        35                  40                  45              


Tyr Asp Val Arg Leu Arg Pro Asn Phe Gly Gly Ala Pro Val Pro Val 
    50                  55                  60                  


Arg Ile Ser Ile Tyr Val Thr Ser Ile Glu Gln Ile Ser Glu Met Asn 
65                  70                  75                  80  


Met Asp Tyr Thr Ile Thr Met Phe Phe His Gln Thr Trp Lys Asp Ser 
                85                  90                  95      


Arg Leu Ala Tyr Tyr Glu Thr Thr Leu Asn Leu Thr Leu Asp Tyr Arg 
            100                 105                 110         


Met His Glu Lys Leu Trp Val Pro Asp Cys Tyr Phe Leu Asn Ser Lys 
        115                 120                 125             


Asp Ala Phe Val His Asp Val Thr Val Glu Asn Arg Val Phe Gln Leu 
    130                 135                 140                 


His Pro Asp Gly Thr Val Arg Tyr Gly Ile Arg Leu Thr Thr Thr Ala 
145                 150                 155                 160 


Ala Cys Ser Leu Asp Leu His Lys Phe Pro Met Asp Lys Gln Ala Cys 
                165                 170                 175     


Asn Leu Val Val Glu Ser Tyr Gly Tyr Thr Val Glu Asp Ile Ile Leu 
            180                 185                 190         


Phe Trp Asp Asp Asn Gly Asn Ala Ile His Met Thr Glu Glu Leu His 
        195                 200                 205             


Ile Pro Gln Phe Thr Phe Leu Gly Arg Thr Ile Thr Ser Lys Glu Val 
    210                 215                 220                 


Tyr Phe Tyr Thr Gly Ser Tyr Ile Arg Leu Ile Leu Lys Phe Gln Val 
225                 230                 235                 240 


Gln Arg Glu Val Asn Ser Tyr 
                245         


<210>  3052
<211>  240
<212>  PRT
<213>  Homo Sapiens

<400>  3052

Val Val Gly Gly Thr Glu Ala Gly Arg Asn Ser Trp Pro Ser Gln Ile 
1               5                   10                  15      


Ser Leu Gln Tyr Arg Ser Gly Gly Ser Arg Tyr His Thr Cys Gly Gly 
            20                  25                  30          


Thr Leu Ile Arg Gln Asn Trp Val Met Thr Ala Ala His Cys Val Asp 
        35                  40                  45              


Tyr Gln Lys Thr Phe Arg Val Val Ala Gly Asp His Asn Leu Ser Gln 
    50                  55                  60                  


Asn Asp Gly Thr Glu Gln Tyr Val Ser Val Gln Lys Ile Val Val His 
65                  70                  75                  80  


Pro Tyr Trp Asn Ser Asp Asn Val Ala Ala Gly Tyr Asp Ile Ala Leu 
                85                  90                  95      


Leu Arg Leu Ala Gln Ser Val Thr Leu Asn Ser Tyr Val Gln Leu Gly 
            100                 105                 110         


Val Leu Pro Gln Glu Gly Ala Ile Leu Ala Asn Asn Ser Pro Cys Tyr 
        115                 120                 125             


Ile Thr Gly Trp Gly Lys Thr Lys Thr Asn Gly Gln Leu Ala Gln Thr 
    130                 135                 140                 


Leu Gln Gln Ala Tyr Leu Pro Ser Val Asp Tyr Ala Ile Cys Ser Ser 
145                 150                 155                 160 


Ser Ser Tyr Trp Gly Ser Thr Val Lys Asn Thr Met Val Cys Ala Gly 
                165                 170                 175     


Gly Asp Gly Val Arg Ser Gly Cys Gln Gly Asp Ser Gly Gly Pro Leu 
            180                 185                 190         


His Cys Leu Val Asn Gly Lys Tyr Ser Val His Gly Val Thr Ser Phe 
        195                 200                 205             


Val Ser Ser Arg Gly Cys Asn Val Ser Arg Lys Pro Thr Val Phe Thr 
    210                 215                 220                 


Gln Val Ser Ala Tyr Ile Ser Trp Ile Asn Asn Val Ile Ala Ser Asn 
225                 230                 235                 240 


<210>  3053
<211>  125
<212>  PRT
<213>  Homo Sapiens

<400>  3053

Gly Ile Leu Asn Leu Asn Lys Met Val Lys Gln Val Thr Gly Lys Met 
1               5                   10                  15      


Pro Ile Leu Ser Tyr Trp Pro Tyr Gly Cys His Cys Gly Leu Gly Gly 
            20                  25                  30          


Arg Gly Gln Pro Lys Asp Ala Thr Asp Trp Cys Cys Gln Thr His Asp 
        35                  40                  45              


Cys Cys Tyr Asp His Leu Lys Thr Gln Gly Cys Ser Ile Tyr Lys Asp 
    50                  55                  60                  


Tyr Tyr Arg Tyr Asn Phe Ser Gln Gly Asn Ile His Cys Ser Asp Lys 
65                  70                  75                  80  


Gly Ser Trp Cys Glu Gln Gln Leu Cys Ala Cys Asp Lys Glu Val Ala 
                85                  90                  95      


Phe Cys Leu Lys Arg Asn Leu Asp Thr Tyr Gln Lys Arg Leu Arg Phe 
            100                 105                 110         


Tyr Trp Arg Pro His Cys Arg Gly Gln Thr Pro Gly Cys 
        115                 120                 125 


<210>  3054
<211>  74
<212>  PRT
<213>  Homo Sapiens

<400>  3054

Asn Leu Thr Thr Ile Ala Ser Trp Leu Ser Trp Leu Gln Tyr Phe Ser 
1               5                   10                  15      


Ile Pro Arg Tyr Gly Phe Thr Ala Leu Gln His Asn Glu Phe Leu Gly 
            20                  25                  30          


Gln Asn Phe Cys Pro Gly Leu Asn Ala Thr Gly Asn Asn Pro Cys Asn 
        35                  40                  45              


Tyr Ala Thr Cys Thr Gly Glu Glu Tyr Leu Val Lys Gln Gly Ile Asp 
    50                  55                  60                  


Leu Ser Pro Trp Gly Leu Trp Lys Asn His 
65                  70                  


<210>  3055
<211>  457
<212>  PRT
<213>  Homo Sapiens

<400>  3055

Ser Leu Leu Glu Pro Arg Asp Pro Val Ala Ser Ser Leu Ser Pro Tyr 
1               5                   10                  15      


Phe Gly Thr Lys Thr Arg Tyr Glu Asp Val Asn Pro Val Leu Leu Ser 
            20                  25                  30          


Gly Pro Glu Ala Pro Trp Arg Asp Pro Glu Leu Leu Glu Gly Thr Cys 
        35                  40                  45              


Thr Pro Val Gln Leu Val Ala Leu Ile Arg His Gly Thr Arg Tyr Pro 
    50                  55                  60                  


Thr Val Lys Gln Ile Arg Lys Leu Arg Gln Leu His Gly Leu Leu Gln 
65                  70                  75                  80  


Ala Arg Gly Ser Arg Asp Gly Gly Ala Ser Ser Thr Gly Ser Arg Asp 
                85                  90                  95      


Leu Gly Ala Ala Leu Ala Asp Trp Pro Leu Trp Tyr Ala Asp Trp Met 
            100                 105                 110         


Asp Gly Gln Leu Val Glu Lys Gly Arg Gln Asp Met Arg Gln Leu Ala 
        115                 120                 125             


Leu Arg Leu Ala Ser Leu Phe Pro Ala Leu Phe Ser Arg Glu Asn Tyr 
    130                 135                 140                 


Gly Arg Leu Arg Leu Ile Thr Ser Ser Lys His Arg Cys Met Asp Ser 
145                 150                 155                 160 


Ser Ala Ala Phe Leu Gln Gly Leu Trp Gln His Tyr His Pro Gly Leu 
                165                 170                 175     


Pro Pro Pro Asp Val Ala Asp Met Glu Phe Gly Pro Pro Thr Val Asn 
            180                 185                 190         


Asp Lys Leu Met Arg Phe Phe Asp His Cys Glu Lys Phe Leu Thr Glu 
        195                 200                 205             


Val Glu Lys Asn Ala Thr Ala Leu Tyr His Val Glu Ala Phe Lys Thr 
    210                 215                 220                 


Gly Pro Glu Met Gln Asn Ile Leu Lys Lys Val Ala Ala Thr Leu Gln 
225                 230                 235                 240 


Val Pro Val Asn Asp Leu Asn Ala Asp Leu Ile Gln Val Ala Phe Phe 
                245                 250                 255     


Thr Cys Ser Phe Asp Leu Ala Ile Lys Gly Val Lys Ser Pro Trp Cys 
            260                 265                 270         


Asp Val Phe Asp Ile Asp Asp Ala Lys Val Leu Glu Tyr Leu Asn Asp 
        275                 280                 285             


Leu Lys Gln Tyr Trp Lys Arg Gly Tyr Gly Tyr Thr Ile Asn Ser Arg 
    290                 295                 300                 


Ser Ser Cys Thr Leu Phe Gln Asp Ile Phe Gln His Leu Asp Lys Ala 
305                 310                 315                 320 


Val Glu Gln Lys Gln Arg Ser Gln Pro Ile Ser Ser Pro Val Ile Leu 
                325                 330                 335     


Gln Phe Gly His Ala Glu Thr Leu Leu Pro Leu Leu Ser Leu Met Gly 
            340                 345                 350         


Tyr Phe Lys Asp Lys Glu Pro Leu Thr Ala Tyr Asn Tyr Lys Lys Gln 
        355                 360                 365             


Met His Arg Lys Phe Arg Ser Gly Leu Ile Val Pro Tyr Ala Ser Asn 
    370                 375                 380                 


Leu Ile Phe Val Leu Tyr His Cys Glu Asn Ala Lys Thr Pro Lys Glu 
385                 390                 395                 400 


Gln Phe Arg Val Gln Met Leu Leu Asn Glu Lys Val Leu Pro Leu Ala 
                405                 410                 415     


Tyr Ser Gln Glu Thr Val Ser Phe Tyr Glu Asp Leu Lys Asn His Tyr 
            420                 425                 430         


Lys Asp Ile Leu Gln Ser Cys Gln Thr Ser Glu Glu Cys Glu Leu Ala 
        435                 440                 445             


Arg Ala Asn Ser Thr Ser Asp Glu Leu 
    450                 455         


<210>  3056
<211>  423
<212>  PRT
<213>  Homo Sapiens

<400>  3056

Ala Pro Pro Pro Cys Arg Cys Met Thr Ser Ser Ser Pro Tyr Gln Glu 
1               5                   10                  15      


Phe Leu Trp Arg Met Gln Arg Pro Gly Asn Ile Asp Ala Pro Ser Tyr 
            20                  25                  30          


Arg Ser Leu Ser Lys Gly Thr Pro Thr Phe Thr Ala His Thr His Met 
        35                  40                  45              


Pro Arg Asn Cys Tyr His Ser Ala Thr Leu Cys Met His Ala Asn Thr 
    50                  55                  60                  


His Tyr Trp Thr Gly Lys Met Ile Asn Pro Ser Cys Pro Gly Gly Leu 
65                  70                  75                  80  


Gly Val Thr Val Cys Trp Thr Tyr Phe Thr Gln Thr Gly Met Ser Asp 
                85                  90                  95      


Gly Gly Gly Val Gln Asp Gln Ala Arg Glu Lys His Val Lys Glu Val 
            100                 105                 110         


Ile Ser Gln Leu Thr Arg Val His Gly Thr Ser Ser Pro Tyr Lys Gly 
        115                 120                 125             


Leu Asp Leu Ser Lys Leu His Glu Thr Leu Arg Thr His Thr Arg Leu 
    130                 135                 140                 


Val Ser Leu Phe Asn Thr Thr Leu Thr Gly Leu His Glu Val Ser Ala 
145                 150                 155                 160 


Gln Asn Pro Thr Asn Cys Trp Ile Cys Leu Pro Leu Asn Phe Arg Pro 
                165                 170                 175     


Tyr Val Ser Ile Pro Val Pro Glu Gln Trp Asn Asn Phe Ser Thr Glu 
            180                 185                 190         


Ile Asn Thr Thr Ser Val Leu Val Gly Pro Leu Val Ser Asn Leu Glu 
        195                 200                 205             


Ile Thr His Thr Ser Asn Leu Thr Cys Val Lys Phe Ser Asn Thr Thr 
    210                 215                 220                 


Tyr Thr Thr Asn Ser Gln Cys Ile Arg Trp Val Thr Pro Pro Thr Gln 
225                 230                 235                 240 


Ile Val Cys Leu Pro Ser Gly Ile Phe Phe Val Cys Gly Thr Ser Ala 
                245                 250                 255     


Tyr Arg Cys Leu Asn Gly Ser Ser Glu Ser Met Cys Phe Leu Ser Phe 
            260                 265                 270         


Leu Val Pro Pro Met Thr Ile Tyr Thr Glu Gln Asp Leu Tyr Ser Tyr 
        275                 280                 285             


Val Ile Ser Lys Pro Arg Asn Lys Arg Val Pro Ile Leu Pro Phe Val 
    290                 295                 300                 


Ile Gly Ala Gly Val Leu Gly Ala Leu Gly Thr Gly Ile Gly Gly Ile 
305                 310                 315                 320 


Thr Thr Ser Thr Gln Phe Tyr Tyr Lys Leu Ser Gln Glu Leu Asn Gly 
                325                 330                 335     


Asp Met Glu Arg Val Ala Asp Ser Leu Val Thr Leu Gln Asp Gln Leu 
            340                 345                 350         


Asn Ser Leu Ala Ala Val Val Leu Gln Asn Arg Arg Ala Leu Asp Leu 
        355                 360                 365             


Leu Thr Ala Glu Arg Gly Gly Thr Cys Leu Phe Leu Gly Glu Glu Cys 
    370                 375                 380                 


Cys Tyr Tyr Val Asn Gln Ser Gly Ile Val Thr Glu Lys Val Lys Glu 
385                 390                 395                 400 


Ile Arg Asp Arg Ile Gln Arg Arg Ala Glu Glu Leu Arg Asn Thr Gly 
                405                 410                 415     


Pro Trp Gly Leu Leu Ser Gln 
            420             


<210>  3057
<211>  712
<212>  PRT
<213>  Homo Sapiens

<400>  3057

Pro Lys Lys Ala Asn Ser Leu Ala Pro Gln Asp Leu Asp Leu Glu Ile 
1               5                   10                  15      


Leu Glu Thr Val Met Gly Gln Leu Asp Ala His Arg Ile Arg Glu Asn 
            20                  25                  30          


Leu Arg Glu Leu Ser Arg Glu Pro His Leu Ala Ser Ser Pro Arg Asp 
        35                  40                  45              


Glu Asp Leu Val Gln Leu Leu Leu Gln Arg Trp Lys Asp Pro Glu Ser 
    50                  55                  60                  


Gly Leu Asp Ser Ala Glu Ala Ser Thr Tyr Glu Val Leu Leu Ser Phe 
65                  70                  75                  80  


Pro Ser Gln Glu Gln Pro Asn Val Val Asp Ile Val Gly Pro Thr Gly 
                85                  90                  95      


Gly Ile Ile His Ser Cys His Arg Thr Glu Glu Asn Val Thr Gly Glu 
            100                 105                 110         


Gln Gly Gly Pro Asp Val Val Gln Pro Tyr Ala Ala Tyr Ala Pro Ser 
        115                 120                 125             


Gly Thr Pro Gln Gly Leu Leu Val Tyr Ala Asn Arg Gly Ala Glu Glu 
    130                 135                 140                 


Asp Phe Lys Glu Leu Gln Thr Gln Gly Ile Lys Leu Glu Gly Thr Ile 
145                 150                 155                 160 


Ala Leu Thr Arg Tyr Gly Gly Val Gly Arg Gly Ala Lys Ala Val Asn 
                165                 170                 175     


Ala Ala Lys His Gly Val Ala Gly Val Leu Val Tyr Thr Asp Pro Ala 
            180                 185                 190         


Asp Ile Asn Asp Gly Leu Ser Ser Pro Asp Glu Thr Phe Pro Asn Ser 
        195                 200                 205             


Trp Tyr Leu Pro Pro Ser Gly Val Glu Arg Gly Ser Tyr Tyr Glu Tyr 
    210                 215                 220                 


Phe Gly Asp Pro Leu Thr Pro Tyr Leu Pro Ala Val Pro Ser Ser Phe 
225                 230                 235                 240 


Arg Val Asp Leu Ala Asn Val Ser Gly Phe Pro Pro Ile Pro Thr Gln 
                245                 250                 255     


Pro Ile Gly Phe Gln Asp Ala Arg Asp Leu Leu Cys Asn Leu Asn Gly 
            260                 265                 270         


Thr Leu Ala Pro Ala Thr Trp Gln Gly Ala Leu Gly Cys His Tyr Arg 
        275                 280                 285             


Leu Gly Pro Gly Phe Arg Pro Asp Gly Asp Phe Pro Ala Asp Ser Gln 
    290                 295                 300                 


Val Asn Val Ser Val Tyr Asn Arg Leu Glu Leu Arg Asn Ser Ser Asn 
305                 310                 315                 320 


Val Leu Gly Ile Ile Arg Gly Ala Val Glu Pro Asp Arg Tyr Val Leu 
                325                 330                 335     


Tyr Gly Asn His Arg Asp Ser Trp Val His Gly Ala Val Asp Pro Ser 
            340                 345                 350         


Ser Gly Thr Ala Val Leu Leu Glu Leu Ser Arg Val Leu Gly Thr Leu 
        355                 360                 365             


Leu Lys Lys Gly Thr Trp Arg Pro Arg Arg Ser Ile Val Phe Ala Ser 
    370                 375                 380                 


Trp Gly Ala Glu Glu Phe Gly Leu Ile Gly Ser Thr Glu Phe Thr Glu 
385                 390                 395                 400 


Glu Phe Phe Asn Lys Leu Gln Glu Arg Thr Val Ala Tyr Ile Asn Val 
                405                 410                 415     


Asp Ile Ser Val Phe Ala Asn Ala Thr Leu Arg Val Gln Gly Thr Pro 
            420                 425                 430         


Pro Val Gln Ser Val Val Phe Ser Ala Thr Lys Glu Ile Arg Ser Pro 
        435                 440                 445             


Gly Pro Gly Asp Leu Ser Ile Tyr Asp Asn Trp Ile Arg Tyr Phe Asn 
    450                 455                 460                 


Arg Ser Ser Pro Val Tyr Gly Leu Val Pro Ser Leu Gly Ser Leu Gly 
465                 470                 475                 480 


Ala Gly Ser Asp Tyr Ala Pro Phe Val His Phe Leu Gly Ile Ser Ser 
                485                 490                 495     


Met Asp Ile Ala Tyr Thr Tyr Asp Arg Ser Lys Thr Ser Ala Arg Ile 
            500                 505                 510         


Tyr Pro Thr Tyr His Thr Ala Phe Asp Thr Phe Asp Tyr Val Asp Lys 
        515                 520                 525             


Phe Leu Asp Pro Gly Phe Ser Ser His Gln Ala Val Ala Arg Thr Ala 
    530                 535                 540                 


Gly Ser Val Ile Leu Arg Leu Ser Asp Ser Phe Phe Leu Pro Leu Lys 
545                 550                 555                 560 


Val Ser Asp Tyr Ser Glu Thr Leu Arg Ser Phe Leu Gln Ala Ala Gln 
                565                 570                 575     


Gln Asp Leu Gly Ala Leu Leu Glu Gln His Ser Ile Ser Leu Gly Pro 
            580                 585                 590         


Leu Val Thr Ala Val Glu Lys Phe Glu Ala Glu Ala Ala Ala Leu Gly 
        595                 600                 605             


Gln Arg Ile Ser Thr Leu Gln Lys Gly Ser Pro Asp Pro Leu Gln Val 
    610                 615                 620                 


Arg Met Leu Asn Asp Gln Leu Met Leu Leu Glu Arg Thr Phe Leu Asn 
625                 630                 635                 640 


Pro Arg Ala Phe Pro Glu Glu Arg Tyr Tyr Ser His Val Leu Trp Ala 
                645                 650                 655     


Pro Arg Thr Gly Ser Val Val Thr Phe Pro Gly Leu Ser Asn Ala Cys 
            660                 665                 670         


Ser Arg Ala Arg Asp Thr Ala Ser Gly Ser Glu Ala Trp Ala Glu Val 
        675                 680                 685             


Gln Arg Gln Leu Ser Ile Val Val Thr Ala Leu Glu Gly Ala Ala Ala 
    690                 695                 700                 


Thr Leu Arg Pro Val Ala Asp Leu 
705                 710         


<210>  3058
<211>  433
<212>  PRT
<213>  Homo Sapiens

<400>  3058

Gln Pro Thr Phe Ile Asn Ser Val Leu Pro Ile Ser Ala Ala Leu Pro 
1               5                   10                  15      


Ser Leu Asp Gln Lys Lys Arg Gly Gly His Lys Ala Cys Cys Leu Leu 
            20                  25                  30          


Thr Pro Pro Pro Pro Pro Leu Phe Pro Pro Pro Phe Phe Arg Gly Gly 
        35                  40                  45              


Arg Ser Pro Leu Leu Ser Pro Asp Met Lys Asn Leu Met Leu Glu Leu 
    50                  55                  60                  


Glu Thr Ser Gln Ser Pro Cys Met Gln Gly Ser Leu Gly Ser Pro Gly 
65                  70                  75                  80  


Pro Pro Gly Pro Gln Gly Pro Pro Gly Leu Pro Gly Lys Thr Gly Pro 
                85                  90                  95      


Lys Gly Glu Lys Gly Glu Leu Gly Arg Pro Gly Arg Lys Gly Arg Pro 
            100                 105                 110         


Gly Pro Pro Gly Val Pro Gly Met Pro Gly Pro Ile Gly Trp Pro Gly 
        115                 120                 125             


Pro Glu Gly Pro Arg Gly Glu Lys Gly Asp Leu Gly Met Met Gly Leu 
    130                 135                 140                 


Pro Gly Ser Arg Gly Pro Met Gly Ser Lys Gly Tyr Pro Gly Ser Arg 
145                 150                 155                 160 


Gly Glu Lys Gly Ser Arg Gly Glu Lys Gly Asp Leu Gly Pro Lys Gly 
                165                 170                 175     


Glu Lys Gly Phe Pro Gly Phe Pro Gly Met Leu Gly Gln Lys Gly Glu 
            180                 185                 190         


Met Gly Pro Lys Gly Glu Pro Gly Ile Ala Gly His Arg Gly Pro Thr 
        195                 200                 205             


Gly Arg Pro Gly Lys Arg Gly Lys Gln Gly Gln Lys Gly Asp Ser Gly 
    210                 215                 220                 


Val Met Gly Pro Pro Gly Lys Pro Gly Pro Ser Gly Gln Pro Gly Arg 
225                 230                 235                 240 


Pro Gly Pro Pro Gly Pro Pro Pro Ala Gly Gln Leu Ile Met Gly Pro 
                245                 250                 255     


Lys Gly Glu Arg Gly Phe Pro Gly Pro Pro Gly Arg Cys Leu Cys Gly 
            260                 265                 270         


Pro Thr Met Asn Val Asn Asn Pro Ser Tyr Gly Glu Ser Val Tyr Gly 
        275                 280                 285             


Pro Ser Ser Pro Arg Val Pro Val Ile Phe Val Val Asn Asn Gln Glu 
    290                 295                 300                 


Glu Leu Glu Arg Leu Asn Thr Gln Asn Ala Ile Ala Phe Arg Arg Asp 
305                 310                 315                 320 


Gln Arg Ser Leu Tyr Phe Lys Asp Ser Leu Gly Trp Leu Pro Ile Gln 
                325                 330                 335     


Leu Thr Pro Phe Tyr Pro Val Asp Tyr Thr Ala Asp Gln His Gly Thr 
            340                 345                 350         


Cys Gly Asp Gly Leu Leu Gln Pro Gly Glu Glu Cys Asp Asp Gly Asn 
        355                 360                 365             


Ser Asp Val Gly Asp Asp Cys Ile Arg Cys His Arg Ala Tyr Cys Gly 
    370                 375                 380                 


Asp Gly His Arg His Glu Gly Val Glu Asp Cys Asp Gly Ser Asp Phe 
385                 390                 395                 400 


Gly Tyr Leu Thr Cys Glu Thr Tyr Leu Pro Gly Ser Tyr Gly Asp Leu 
                405                 410                 415     


Gln Cys Thr Gln Tyr Cys Tyr Ile Asp Ser Thr Pro Cys Arg Tyr Phe 
            420                 425                 430         


Thr 
    


<210>  3059
<211>  508
<212>  PRT
<213>  Homo Sapiens

<400>  3059

Gln Asp Val Val Asp Leu Asp Phe Phe Thr Gln Glu Pro Leu His Leu 
1               5                   10                  15      


Val Ser Pro Ser Phe Leu Ser Val Thr Ile Asp Ala Asn Leu Ala Thr 
            20                  25                  30          


Asp Pro Arg Phe Leu Ile Leu Leu Gly Ser Pro Lys Leu Arg Thr Leu 
        35                  40                  45              


Ala Arg Gly Leu Ser Pro Ala Tyr Leu Arg Phe Gly Gly Thr Lys Thr 
    50                  55                  60                  


Asp Phe Leu Ile Phe Asp Pro Lys Lys Glu Ser Thr Phe Glu Glu Arg 
65                  70                  75                  80  


Ser Tyr Trp Gln Ser Gln Val Asn Gln Asp Ile Cys Lys Tyr Gly Ser 
                85                  90                  95      


Ile Pro Pro Asp Val Glu Glu Lys Leu Arg Leu Glu Trp Pro Tyr Gln 
            100                 105                 110         


Glu Gln Leu Leu Leu Arg Glu His Tyr Gln Lys Lys Phe Lys Asn Ser 
        115                 120                 125             


Thr Tyr Ser Arg Ser Ser Val Asp Val Leu Tyr Thr Phe Ala Asn Cys 
    130                 135                 140                 


Ser Gly Leu Asp Leu Ile Phe Gly Leu Asn Ala Leu Leu Arg Thr Ala 
145                 150                 155                 160 


Asp Leu Gln Trp Asn Ser Ser Asn Ala Gln Leu Leu Leu Asp Tyr Cys 
                165                 170                 175     


Ser Ser Lys Gly Tyr Asn Ile Ser Trp Glu Leu Gly Asn Glu Pro Asn 
            180                 185                 190         


Ser Phe Leu Lys Lys Ala Asp Ile Phe Ile Asn Gly Ser Gln Leu Gly 
        195                 200                 205             


Glu Asp Phe Ile Gln Leu His Lys Leu Leu Arg Lys Ser Thr Phe Lys 
    210                 215                 220                 


Asn Ala Lys Leu Tyr Gly Pro Asp Val Gly Gln Pro Arg Arg Lys Thr 
225                 230                 235                 240 


Ala Lys Met Leu Lys Ser Phe Leu Lys Ala Gly Gly Glu Val Ile Asp 
                245                 250                 255     


Ser Val Thr Trp His His Tyr Tyr Leu Asn Gly Arg Thr Ala Thr Arg 
            260                 265                 270         


Glu Asp Phe Leu Asn Pro Asp Val Leu Asp Ile Phe Ile Ser Ser Val 
        275                 280                 285             


Gln Lys Val Phe Gln Val Val Glu Ser Thr Arg Pro Gly Lys Lys Val 
    290                 295                 300                 


Trp Leu Gly Glu Thr Ser Ser Ala Tyr Gly Gly Gly Ala Pro Leu Leu 
305                 310                 315                 320 


Ser Asp Thr Phe Ala Ala Gly Phe Met Trp Leu Asp Lys Leu Gly Leu 
                325                 330                 335     


Ser Ala Arg Met Gly Ile Glu Val Val Met Arg Gln Val Phe Phe Gly 
            340                 345                 350         


Ala Gly Asn Tyr His Leu Val Asp Glu Asn Phe Asp Pro Leu Pro Asp 
        355                 360                 365             


Tyr Trp Leu Ser Leu Leu Phe Lys Lys Leu Val Gly Thr Lys Val Leu 
    370                 375                 380                 


Met Ala Ser Val Gln Gly Ser Lys Arg Arg Lys Leu Arg Val Tyr Leu 
385                 390                 395                 400 


His Cys Thr Asn Thr Asp Asn Pro Arg Tyr Lys Glu Gly Asp Leu Thr 
                405                 410                 415     


Leu Tyr Ala Ile Asn Leu His Asn Val Thr Lys Tyr Leu Arg Leu Pro 
            420                 425                 430         


Tyr Pro Phe Ser Asn Lys Gln Val Asp Lys Tyr Leu Leu Arg Pro Leu 
        435                 440                 445             


Gly Pro His Gly Leu Leu Ser Lys Ser Val Gln Leu Asn Gly Leu Thr 
    450                 455                 460                 


Leu Lys Met Val Asp Asp Gln Thr Leu Pro Pro Leu Met Glu Lys Pro 
465                 470                 475                 480 


Leu Arg Pro Gly Ser Ser Leu Gly Leu Pro Ala Phe Ser Tyr Ser Phe 
                485                 490                 495     


Phe Val Ile Arg Asn Ala Lys Val Ala Ala Cys Ile 
            500                 505             


<210>  3060
<211>  93
<212>  PRT
<213>  Homo Sapiens

<400>  3060

Thr Ala Gln Lys Pro Tyr Cys Asn Thr Ser Trp Ile Leu Ala Val Gly 
1               5                   10                  15      


Pro His Leu Ser Lys Ala Glu Gln Leu Asn Leu Thr Ile Pro Gln Ala 
            20                  25                  30          


Pro Asn Gly Ser Phe Leu Thr Cys Phe Met Tyr Leu Pro Val Pro Trp 
        35                  40                  45              


Asn Leu Asp Ser Ile Ile Gln Phe Gly Leu Asn Asp Thr Asp Thr Cys 
    50                  55                  60                  


Gln Asp Gly Trp Ile Tyr Pro Asp Ala Lys Lys Arg Ser Leu Ile Asn 
65                  70                  75                  80  


Glu Phe Asp Leu Val Cys Gly Met Glu Thr Lys Lys Asp 
                85                  90              


<210>  3061
<211>  162
<212>  PRT
<213>  Homo Sapiens

<400>  3061

Arg Arg Ser Gln Asp Leu His Cys Gly Ala Cys Arg Ala Leu Val Asp 
1               5                   10                  15      


Glu Leu Glu Trp Glu Ile Ala Gln Val Asp Pro Lys Lys Thr Ile Gln 
            20                  25                  30          


Met Gly Ser Phe Arg Ile Asn Pro Asp Gly Ser Gln Ser Val Val Glu 
        35                  40                  45              


Val Pro Tyr Ala Arg Ser Glu Ala His Leu Thr Glu Leu Leu Glu Glu 
    50                  55                  60                  


Ile Cys Asp Arg Met Lys Glu Tyr Gly Glu Gln Ile Asp Pro Ser Thr 
65                  70                  75                  80  


His Arg Lys Asn Tyr Val Arg Val Val Gly Arg Asn Gly Glu Ser Ser 
                85                  90                  95      


Glu Leu Asp Leu Gln Gly Ile Arg Ile Asp Ser Asp Ile Ser Gly Thr 
            100                 105                 110         


Leu Lys Phe Ala Cys Glu Ser Ile Val Glu Glu Tyr Glu Asp Glu Leu 
        115                 120                 125             


Ile Glu Phe Phe Ser Arg Glu Ala Asp Asn Val Lys Asp Lys Leu Cys 
    130                 135                 140                 


Ser Lys Arg Thr Asp Leu Cys Asp His Ala Leu His Ile Ser His Asp 
145                 150                 155                 160 


Glu Leu 
        


<210>  3062
<211>  413
<212>  PRT
<213>  Homo Sapiens

<400>  3062

Arg Arg Arg Gln Ala Pro Ala Gly Ser Pro Arg Gly Leu Arg Lys Gly 
1               5                   10                  15      


Ala Ala Pro Ala Arg Glu Arg Arg Gly Arg Glu Gln Ser Thr Leu Glu 
            20                  25                  30          


Ser Glu Glu Trp Asn Pro Trp Glu Gly Asp Glu Lys Asn Glu Gln Gln 
        35                  40                  45              


His Arg Phe Lys Thr Ser Leu Gln Ile Leu Asp Lys Ser Thr Lys Gly 
    50                  55                  60                  


Lys Thr Asp Leu Ser Val Gln Ile Trp Gly Lys Ala Ala Ile Gly Leu 
65                  70                  75                  80  


Tyr Leu Trp Glu His Ile Phe Glu Gly Leu Leu Asp Pro Ser Asp Val 
                85                  90                  95      


Thr Ala Gln Trp Arg Glu Gly Lys Ser Ile Val Gly Arg Thr Gln Tyr 
            100                 105                 110         


Ser Phe Ile Thr Gly Pro Ala Val Ile Pro Gly Tyr Phe Ser Val Asp 
        115                 120                 125             


Val Asn Asn Val Val Leu Ile Leu Asn Gly Arg Glu Lys Ala Lys Ile 
    130                 135                 140                 


Phe Tyr Ala Thr Gln Trp Leu Leu Tyr Ala Gln Asn Leu Val Gln Ile 
145                 150                 155                 160 


Gln Lys Leu Gln His Leu Ala Val Val Leu Leu Gly Asn Glu His Cys 
                165                 170                 175     


Asp Asn Glu Trp Ile Asn Pro Phe Leu Lys Arg Asn Gly Gly Phe Val 
            180                 185                 190         


Glu Leu Leu Phe Ile Ile Tyr Asp Ser Pro Trp Ile Asn Asp Val Asp 
        195                 200                 205             


Val Phe Gln Trp Pro Leu Gly Val Ala Thr Tyr Arg Asn Phe Pro Val 
    210                 215                 220                 


Val Glu Ala Ser Trp Ser Met Leu His Asp Glu Arg Pro Tyr Leu Cys 
225                 230                 235                 240 


Asn Phe Leu Gly Thr Ile Tyr Glu Asn Ser Ser Arg Gln Ala Leu Met 
                245                 250                 255     


Asn Ile Leu Lys Lys Asp Gly Asn Asp Lys Leu Cys Trp Val Ser Ala 
            260                 265                 270         


Arg Glu His Trp Gln Pro Gln Glu Thr Asn Glu Ser Leu Lys Asn Tyr 
        275                 280                 285             


Gln Asp Ala Leu Leu Gln Ser Asp Leu Thr Leu Cys Pro Val Gly Val 
    290                 295                 300                 


Asn Thr Glu Cys Tyr Arg Ile Tyr Glu Ala Cys Ser Tyr Gly Ser Ile 
305                 310                 315                 320 


Pro Val Val Glu Asp Val Met Thr Ala Gly Asn Cys Gly Asn Thr Ser 
                325                 330                 335     


Val His His Gly Ala Pro Leu Gln Leu Leu Lys Ser Met Gly Ala Pro 
            340                 345                 350         


Phe Ile Phe Ile Lys Asn Trp Lys Glu Leu Pro Ala Val Leu Glu Lys 
        355                 360                 365             


Glu Lys Thr Ile Ile Leu Gln Glu Lys Ile Glu Arg Arg Lys Met Leu 
    370                 375                 380                 


Leu Gln Trp Tyr Gln His Phe Lys Thr Glu Leu Lys Met Lys Phe Thr 
385                 390                 395                 400 


Asn Ile Leu Glu Ser Ser Phe Leu Met Asn Asn Lys Ser 
                405                 410             


<210>  3063
<211>  986
<212>  PRT
<213>  Homo Sapiens

<400>  3063

Ala Gly Pro Ile Arg Ala Phe Val Val Pro His Ser His Met Asp Val 
1               5                   10                  15      


Gly Trp Val Tyr Thr Val Gln Glu Ser Met Arg Ala Tyr Ala Ala Asn 
            20                  25                  30          


Val Tyr Thr Ser Val Val Glu Glu Leu Ala Arg Gly Gln Gln Arg Arg 
        35                  40                  45              


Phe Ile Ala Val Glu Gln Glu Phe Phe Arg Leu Trp Trp Asp Gly Val 
    50                  55                  60                  


Ala Ser Asp Gln Gln Lys Tyr Gln Val Arg Gln Leu Leu Glu Glu Gly 
65                  70                  75                  80  


Arg Leu Glu Phe Val Ile Gly Gly Gln Val Met His Asp Glu Ala Val 
                85                  90                  95      


Thr His Leu Asp Asp Gln Ile Leu Gln Leu Thr Glu Gly His Gly Phe 
            100                 105                 110         


Leu Tyr Glu Thr Phe Gly Ile Arg Pro Gln Phe Ser Trp His Val Asp 
        115                 120                 125             


Pro Phe Gly Ala Ser Ala Thr Thr Pro Thr Leu Phe Ala Leu Ala Gly 
    130                 135                 140                 


Phe Asn Ala His Leu Gly Ser Arg Ile Asp Tyr Asp Leu Lys Ala Ala 
145                 150                 155                 160 


Met Gln Glu Ala Arg Gly Leu Gln Phe Val Trp Arg Gly Ser Pro Ser 
                165                 170                 175     


Leu Ser Glu Arg Gln Glu Ile Phe Thr His Ile Met Asp Gln Tyr Ser 
            180                 185                 190         


Tyr Cys Thr Pro Ser His Ile Pro Phe Ser Asn Arg Ser Gly Phe Tyr 
        195                 200                 205             


Trp Asn Gly Val Ala Val Phe Pro Lys Pro Pro Pro Asp Gly Val Tyr 
    210                 215                 220                 


Pro Asn Met Ser Glu Pro Val Thr Pro Ala Asn Ile Asn Leu Tyr Ala 
225                 230                 235                 240 


Glu Ala Leu Val Ala Asn Val Lys Gln Arg Ala Ala Trp Phe Arg Thr 
                245                 250                 255     


Pro His Val Leu Trp Pro Trp Gly Cys Asp Lys Gln Phe Phe Asn Ala 
            260                 265                 270         


Ser Val Gln Phe Ala Asn Met Asp Pro Leu Leu Asp His Ile Asn Ser 
        275                 280                 285             


His Ala Ala Glu Leu Gly Val Ser Val Gln Tyr Ala Thr Leu Gly Asp 
    290                 295                 300                 


Tyr Phe Arg Ala Leu His Ala Leu Asn Val Thr Trp Arg Val Arg Asp 
305                 310                 315                 320 


His His Asp Phe Leu Pro Tyr Ser Thr Glu Pro Phe Gln Ala Trp Thr 
                325                 330                 335     


Gly Phe Tyr Thr Ser Arg Ser Ser Leu Lys Gly Leu Ala Arg Arg Ala 
            340                 345                 350         


Ser Ala Leu Leu Tyr Ala Gly Glu Ser Met Phe Thr Arg Tyr Leu Trp 
        355                 360                 365             


Pro Ala Pro Arg Gly His Leu Asp Pro Thr Trp Ala Leu Gln Gln Leu 
    370                 375                 380                 


Gln Gln Leu Arg Trp Ala Val Ser Glu Val Gln His His Asp Ala Ile 
385                 390                 395                 400 


Thr Gly Thr Glu Ser Pro Lys Val Arg Asp Met Tyr Ala Thr His Leu 
                405                 410                 415     


Ala Ser Gly Met Leu Gly Val Arg Lys Leu Met Ala Ser Ile Val Leu 
            420                 425                 430         


Asp Glu Leu Gln Pro Gln Ala Pro Met Ala Ala Ser Ser Asp Ala Gly 
        435                 440                 445             


Pro Ala Gly His Phe Ala Ser Val Tyr Asn Pro Leu Ala Trp Thr Val 
    450                 455                 460                 


Thr Thr Ile Val Thr Leu Thr Val Gly Phe Pro Gly Val Arg Val Thr 
465                 470                 475                 480 


Asp Glu Ala Gly His Pro Val Pro Ser Gln Ile Gln Asn Ser Thr Glu 
                485                 490                 495     


Thr Pro Ser Ala Tyr Asp Leu Leu Ile Leu Thr Thr Ile Pro Gly Leu 
            500                 505                 510         


Ser Tyr Arg His Tyr Ser Ile Arg Pro Thr Ala Gly Ala Gln Glu Gly 
        515                 520                 525             


Thr Gln Glu Pro Ala Ala Thr Val Ala Ser Thr Leu Gln Phe Gly Arg 
    530                 535                 540                 


Arg Leu Arg Arg Arg Thr Ser His Ala Gly Arg Tyr Leu Val Pro Val 
545                 550                 555                 560 


Ala Asn Asp Cys Tyr Ile Val Leu Leu Asp Gln Asp Thr Asn Leu Met 
                565                 570                 575     


His Ser Ile Trp Glu Arg Gln Ser Asn Arg Thr Val Arg Val Thr Gln 
            580                 585                 590         


Glu Phe Leu Glu Tyr His Val Asn Gly Asp Val Lys Gln Gly Pro Ile 
        595                 600                 605             


Ser Asp Asn Tyr Leu Phe Thr Pro Gly Lys Ala Ala Val Pro Ala Trp 
    610                 615                 620                 


Glu Ala Val Glu Met Glu Ile Val Ala Gly Gln Leu Val Thr Glu Ile 
625                 630                 635                 640 


Arg Gln Tyr Phe Tyr Arg Asn Met Thr Ala Gln Asn Tyr Thr Tyr Ala 
                645                 650                 655     


Ile Arg Ser Arg Leu Thr His Val Pro Gln Gly His Asp Gly Glu Leu 
            660                 665                 670         


Leu Cys His Arg Ile Glu Gln Glu Tyr Gln Ala Gly Pro Leu Glu Leu 
        675                 680                 685             


Asn Arg Glu Ala Val Leu Arg Thr Ser Thr Asn Leu Asn Ser Gln Gln 
    690                 695                 700                 


Val Ile Tyr Ser Asp Asn Asn Gly Tyr Gln Met Gln Arg Arg Pro Tyr 
705                 710                 715                 720 


Val Ser Tyr Val Asn Asn Ser Ile Ala Arg Asn Tyr Tyr Pro Met Val 
                725                 730                 735     


Gln Ser Ala Phe Met Glu Asp Gly Lys Ser Arg Leu Val Leu Leu Ser 
            740                 745                 750         


Glu Arg Ala His Gly Ile Ser Ser Gln Gly Asn Gly Gln Val Glu Val 
        755                 760                 765             


Met Leu His Arg Arg Leu Trp Asn Asn Phe Asp Trp Asp Leu Gly Tyr 
    770                 775                 780                 


Asn Leu Thr Leu Asn Asp Thr Ser Val Val His Pro Val Leu Trp Leu 
785                 790                 795                 800 


Leu Leu Gly Ser Trp Ser Leu Thr Thr Ala Leu Arg Gln Arg Ser Ala 
                805                 810                 815     


Leu Ala Leu Gln His Arg Pro Val Val Leu Phe Gly Asp Leu Ala Gly 
            820                 825                 830         


Thr Ala Pro Lys Leu Pro Gly Pro Gln Gln Gln Glu Ala Val Thr Leu 
        835                 840                 845             


Pro Pro Asn Leu His Leu Gln Ile Leu Ser Ile Pro Gly Trp Arg Tyr 
    850                 855                 860                 


Ser Ser Asn His Thr Glu His Ser Gln Asn Leu Arg Lys Gly His Arg 
865                 870                 875                 880 


Gly Glu Ala Gln Ala Asp Leu Arg Arg Val Leu Leu Arg Leu Tyr His 
                885                 890                 895     


Leu Tyr Glu Val Gly Glu Asp Pro Val Leu Ser Gln Pro Val Thr Val 
            900                 905                 910         


Asn Leu Glu Ala Val Leu Gln Ala Leu Gly Ser Val Val Ala Val Glu 
        915                 920                 925             


Glu Arg Ser Leu Thr Gly Thr Trp Asp Leu Ser Met Leu His Arg Trp 
    930                 935                 940                 


Ser Trp Arg Thr Gly Pro Gly Arg His Arg Gly Asp Thr Thr Ser Pro 
945                 950                 955                 960 


Ser Arg Pro Pro Gly Gly Pro Ile Ile Thr Val His Pro Lys Glu Ile 
                965                 970                 975     


Arg Thr Phe Phe Ile His Phe Gln Gln Gln 
            980                 985     


<210>  3064
<211>  408
<212>  PRT
<213>  Homo Sapiens

<400>  3064

Ser Gly Gln Glu Phe Trp Pro Gly Gln Ser Ala Ala Asp Ile Leu Ser 
1               5                   10                  15      


Gly Ala Ala Ser Arg Arg Arg Tyr Leu Leu Tyr Asp Val Asn Pro Pro 
            20                  25                  30          


Glu Gly Phe Asn Leu Arg Arg Asp Val Tyr Ile Arg Ile Ala Ser Leu 
        35                  40                  45              


Leu Lys Thr Leu Leu Lys Thr Glu Glu Trp Val Leu Val Leu Pro Pro 
    50                  55                  60                  


Trp Gly Arg Leu Tyr His Trp Gln Ser Pro Asp Ile His Gln Val Arg 
65                  70                  75                  80  


Ile Pro Trp Ser Glu Phe Phe Asp Leu Pro Ser Leu Asn Lys Asn Ile 
                85                  90                  95      


Pro Val Ile Glu Tyr Glu Gln Phe Ile Ala Glu Ser Gly Gly Pro Phe 
            100                 105                 110         


Ile Asp Gln Val Tyr Val Leu Gln Ser Tyr Ala Glu Gly Trp Lys Glu 
        115                 120                 125             


Gly Thr Trp Glu Glu Lys Val Asp Glu Arg Pro Cys Ile Asp Gln Leu 
    130                 135                 140                 


Leu Tyr Ser Gln Asp Lys His Glu Tyr Tyr Arg Gly Trp Phe Trp Gly 
145                 150                 155                 160 


Tyr Glu Glu Thr Arg Gly Leu Asn Val Ser Cys Leu Ser Val Gln Gly 
                165                 170                 175     


Ser Ala Ser Ile Val Ala Pro Leu Leu Leu Arg Asn Thr Ser Ala Arg 
            180                 185                 190         


Ser Val Met Leu Asp Arg Ala Glu Asn Leu Leu His Asp His Tyr Gly 
        195                 200                 205             


Gly Lys Glu Tyr Trp Asp Thr Arg Arg Ser Met Val Phe Ala Arg His 
    210                 215                 220                 


Leu Arg Glu Val Gly Asp Glu Phe Arg Ser Arg His Leu Asn Ser Thr 
225                 230                 235                 240 


Asp Asp Ala Asp Arg Ile Pro Phe Gln Glu Asp Trp Met Lys Met Lys 
                245                 250                 255     


Val Lys Leu Gly Ser Ala Leu Gly Gly Pro Tyr Leu Gly Val His Leu 
            260                 265                 270         


Arg Arg Lys Asp Phe Ile Trp Gly His Arg Gln Asp Val Pro Ser Leu 
        275                 280                 285             


Glu Gly Ala Val Arg Lys Ile Arg Ser Leu Met Lys Thr His Arg Leu 
    290                 295                 300                 


Asp Lys Val Phe Val Ala Thr Asp Ala Val Arg Lys Glu Tyr Glu Glu 
305                 310                 315                 320 


Leu Lys Lys Leu Leu Pro Glu Met Val Arg Phe Glu Pro Thr Trp Glu 
                325                 330                 335     


Glu Leu Glu Leu Tyr Lys Asp Gly Gly Val Ala Ile Ile Asp Gln Trp 
            340                 345                 350         


Ile Cys Ala His Ala Arg Phe Phe Ile Gly Thr Ser Val Ser Thr Phe 
        355                 360                 365             


Ser Phe Arg Ile His Glu Glu Arg Glu Ile Leu Gly Leu Asp Pro Lys 
    370                 375                 380                 


Thr Thr Tyr Asn Arg Phe Cys Gly Asp Gln Glu Lys Ala Cys Glu Gln 
385                 390                 395                 400 


Pro Thr His Trp Lys Ile Thr Tyr 
                405             


<210>  3065
<211>  226
<212>  PRT
<213>  Homo Sapiens

<400>  3065

Gln Ala Phe Ser Asp Ser Asn Asp Glu Arg Glu Ser Ser Pro Pro Glu 
1               5                   10                  15      


Lys Glu Glu Ala Gln Glu Lys Thr Gly Lys Thr Glu Pro Ser Phe Thr 
            20                  25                  30          


Lys Glu Asn Ser Ser Lys Ile Pro Lys Lys Gly Phe Val Glu Val Thr 
        35                  40                  45              


Glu Leu Thr Asp Val Thr Tyr Thr Ser Asn Leu Val Arg Leu Arg Pro 
    50                  55                  60                  


Gly His Met Asn Val Val Leu Ile Leu Ser Asn Ser Thr Lys Thr Ser 
65                  70                  75                  80  


Leu Leu Gln Lys Phe Ala Leu Glu Val Tyr Thr Phe Thr Gly Ser Ser 
                85                  90                  95      


Cys Leu His Phe Ser Phe Leu Ser Leu Asp Lys His Arg Glu Trp Leu 
            100                 105                 110         


Glu Tyr Leu Leu Glu Phe Ala Gln Asp Ala Ala Pro Ile Pro Asn Gln 
        115                 120                 125             


Tyr Asp Lys His Phe Met Glu Arg Asp Tyr Thr Gly Tyr Val Leu Ala 
    130                 135                 140                 


Leu Asn Gly His Lys Lys Tyr Phe Cys Leu Phe Lys Pro Gln Lys Thr 
145                 150                 155                 160 


Val Glu Glu Glu Glu Ala Ile Gly Ser Cys Ser Asp Val Asp Ser Ser 
                165                 170                 175     


Leu Tyr Leu Gly Glu Ser Arg Gly Lys Pro Ser Cys Gly Leu Gly Ser 
            180                 185                 190         


Arg Pro Ile Lys Gly Lys Leu Ser Lys Leu Ser Leu Trp Met Glu Arg 
        195                 200                 205             


Leu Leu Glu Gly Ser Leu Gln Arg Phe Tyr Ile Pro Ser Trp Pro Glu 
    210                 215                 220                 


Leu Asp 
225     


<210>  3066
<211>  54
<212>  PRT
<213>  Homo Sapiens

<400>  3066

Leu Pro Thr Gln Arg Glu Asp Gly Asn Pro Cys Asp Phe Asp Trp Arg 
1               5                   10                  15      


Glu Val Glu Ile Leu Met Phe Leu Ser Ala Ile Val Met Met Lys Asn 
            20                  25                  30          


Arg Arg Ser Ile Thr Val Glu Gln His Ile Gly Asn Ile Phe Met Phe 
        35                  40                  45              


Ser Lys Val Ala Asn Thr 
    50                  


<210>  3067
<211>  271
<212>  PRT
<213>  Homo Sapiens

<400>  3067

Val Thr Glu His Val Leu Ala Asn Asn Asp Val Ser Cys Asp His Pro 
1               5                   10                  15      


Ser Asn Thr Val Pro Ser Gly Ser Asn Gln Asp Leu Gly Ala Gly Ala 
            20                  25                  30          


Gly Glu Asp Ala Arg Ser Asp Asp Ser Ser Ser Arg Ile Ile Asn Gly 
        35                  40                  45              


Ser Asp Cys Asp Met His Thr Gln Pro Trp Gln Ala Ala Leu Leu Leu 
    50                  55                  60                  


Arg Pro Asn Gln Leu Tyr Cys Gly Ala Val Leu Val His Pro Gln Trp 
65                  70                  75                  80  


Leu Leu Thr Ala Ala His Cys Arg Lys Lys Val Phe Arg Val Arg Leu 
                85                  90                  95      


Gly His Tyr Ser Leu Ser Pro Val Tyr Glu Ser Gly Gln Gln Met Phe 
            100                 105                 110         


Gln Gly Val Lys Ser Ile Pro His Pro Gly Tyr Ser His Pro Gly His 
        115                 120                 125             


Ser Asn Asp Leu Met Leu Ile Lys Leu Asn Arg Arg Ile Arg Pro Thr 
    130                 135                 140                 


Lys Asp Val Arg Pro Ile Asn Val Ser Ser His Cys Pro Ser Ala Gly 
145                 150                 155                 160 


Thr Lys Cys Leu Val Ser Gly Trp Gly Thr Thr Lys Ser Pro Gln Val 
                165                 170                 175     


His Phe Pro Lys Val Leu Gln Cys Leu Asn Ile Ser Val Leu Ser Gln 
            180                 185                 190         


Lys Arg Cys Glu Asp Ala Tyr Pro Arg Gln Ile Asp Asp Thr Met Phe 
        195                 200                 205             


Cys Ala Gly Asp Lys Ala Gly Arg Asp Ser Cys Gln Gly Asp Ser Gly 
    210                 215                 220                 


Gly Pro Val Val Cys Asn Gly Ser Leu Gln Gly Leu Val Ser Trp Gly 
225                 230                 235                 240 


Asp Tyr Pro Cys Ala Arg Pro Asn Arg Pro Gly Val Tyr Thr Asn Leu 
                245                 250                 255     


Cys Lys Phe Thr Lys Trp Ile Gln Glu Thr Ile Gln Ala Asn Ser 
            260                 265                 270     


<210>  3068
<211>  102
<212>  PRT
<213>  Homo Sapiens

<400>  3068

Cys Tyr Thr Leu Phe Tyr Leu Phe Ala Ser Phe Val Ser Val Leu Pro 
1               5                   10                  15      


Trp Gly Ser Cys Asn Asn Pro Trp Asn Thr Pro Glu Cys Lys Asp Lys 
            20                  25                  30          


Thr Lys Leu Leu Leu Asp Ser Cys Val Ile Ser Asp His Pro Lys Ile 
        35                  40                  45              


Gln Ile Lys Asn Ser Thr Phe Cys Met Thr Ala Tyr Pro Asn Val Thr 
    50                  55                  60                  


Met Val Asn Phe Thr Ser Gln Ala Asn Lys Thr Phe Val Ser Gly Ser 
65                  70                  75                  80  


Glu Glu Tyr Phe Lys Tyr Phe Val Leu Lys Ile Ser Ala Gly Ile Glu 
                85                  90                  95      


Tyr Pro Gly Glu Ile Arg 
            100         


<210>  3069
<211>  311
<212>  PRT
<213>  Homo Sapiens

<400>  3069

Asp Gly Asp Leu Thr Leu Leu Trp Ala Glu Trp Gln Gly Arg Arg Pro 
1               5                   10                  15      


Glu Trp Glu Leu Thr Asp Met Val Val Trp Val Thr Gly Ala Ser Ser 
            20                  25                  30          


Gly Ile Gly Glu Glu Leu Ala Tyr Gln Leu Ser Lys Leu Gly Val Ser 
        35                  40                  45              


Leu Val Leu Ser Ala Arg Arg Val His Glu Leu Glu Arg Val Lys Arg 
    50                  55                  60                  


Arg Cys Leu Glu Asn Gly Asn Leu Lys Glu Lys Asp Ile Leu Val Leu 
65                  70                  75                  80  


Pro Leu Asp Leu Thr Asp Thr Gly Ser His Glu Ala Ala Thr Lys Ala 
                85                  90                  95      


Val Leu Gln Glu Phe Gly Arg Ile Asp Ile Leu Val Asn Asn Gly Gly 
            100                 105                 110         


Met Ser Gln Arg Ser Leu Cys Met Asp Thr Ser Leu Asp Val Tyr Arg 
        115                 120                 125             


Lys Leu Ile Glu Leu Asn Tyr Leu Gly Thr Val Ser Leu Thr Lys Cys 
    130                 135                 140                 


Val Leu Pro His Met Ile Glu Arg Lys Gln Gly Lys Ile Val Thr Val 
145                 150                 155                 160 


Asn Ser Ile Leu Gly Ile Ile Ser Val Pro Leu Ser Ile Gly Tyr Cys 
                165                 170                 175     


Ala Ser Lys His Ala Leu Arg Gly Phe Phe Asn Gly Leu Arg Thr Glu 
            180                 185                 190         


Leu Ala Thr Tyr Pro Gly Ile Ile Val Ser Asn Ile Cys Pro Gly Pro 
        195                 200                 205             


Val Gln Ser Asn Ile Val Glu Asn Ser Leu Ala Gly Glu Val Thr Lys 
    210                 215                 220                 


Thr Ile Gly Asn Asn Gly Asp Gln Ser His Lys Met Thr Thr Ser Arg 
225                 230                 235                 240 


Cys Val Arg Leu Met Leu Ile Ser Met Ala Asn Asp Leu Lys Glu Val 
                245                 250                 255     


Trp Ile Ser Glu Gln Pro Phe Leu Leu Val Thr Tyr Leu Trp Gln Tyr 
            260                 265                 270         


Met Pro Thr Trp Ala Trp Trp Ile Thr Asn Lys Met Gly Lys Lys Arg 
        275                 280                 285             


Ile Glu Asn Phe Lys Ser Gly Val Asp Ala Asp Ser Ser Tyr Phe Lys 
    290                 295                 300                 


Ile Phe Lys Thr Lys His Asp 
305                 310     


<210>  3070
<211>  749
<212>  PRT
<213>  Homo Sapiens

<400>  3070

Gln Tyr Asp Ser Trp Pro His Tyr Pro Glu Tyr Phe Gln Gln Pro Ala 
1               5                   10                  15      


Pro Glu Tyr His Gln Pro Gln Ala Pro Ala Asn Val Ala Lys Ile Gln 
            20                  25                  30          


Leu Arg Leu Ala Gly Gln Lys Arg Lys His Ser Glu Gly Arg Val Glu 
        35                  40                  45              


Val Tyr Tyr Asp Gly Gln Trp Gly Thr Val Cys Asp Asp Asp Phe Ser 
    50                  55                  60                  


Ile His Ala Ala His Val Val Cys Arg Glu Leu Gly Tyr Val Glu Ala 
65                  70                  75                  80  


Lys Ser Trp Thr Ala Ser Ser Ser Tyr Gly Lys Gly Glu Gly Pro Ile 
                85                  90                  95      


Trp Leu Asp Asn Leu His Cys Thr Gly Asn Glu Ala Thr Leu Ala Ala 
            100                 105                 110         


Cys Thr Ser Asn Gly Trp Gly Val Thr Asp Cys Lys His Thr Glu Asp 
        115                 120                 125             


Val Gly Val Val Cys Ser Asp Lys Arg Ile Pro Gly Phe Lys Phe Asp 
    130                 135                 140                 


Asn Ser Leu Ile Asn Gln Ile Glu Asn Leu Asn Ile Gln Val Glu Asp 
145                 150                 155                 160 


Ile Arg Ile Arg Ala Ile Leu Ser Thr Tyr Arg Lys Arg Thr Pro Val 
                165                 170                 175     


Met Glu Gly Tyr Val Glu Val Lys Glu Gly Lys Thr Trp Lys Gln Ile 
            180                 185                 190         


Cys Asp Lys His Trp Thr Ala Lys Asn Ser Arg Val Val Cys Gly Met 
        195                 200                 205             


Phe Gly Phe Pro Gly Glu Arg Thr Tyr Asn Thr Lys Val Tyr Lys Met 
    210                 215                 220                 


Phe Ala Ser Arg Arg Lys Gln Arg Tyr Trp Pro Phe Ser Met Asp Cys 
225                 230                 235                 240 


Thr Gly Thr Glu Ala His Ile Ser Ser Cys Lys Leu Gly Pro Gln Val 
                245                 250                 255     


Ser Leu Asp Pro Met Lys Asn Val Thr Cys Glu Asn Gly Leu Pro Ala 
            260                 265                 270         


Val Val Ser Cys Val Pro Gly Gln Val Phe Ser Pro Asp Gly Pro Ser 
        275                 280                 285             


Arg Phe Arg Lys Ala Tyr Lys Pro Glu Gln Pro Leu Val Arg Leu Arg 
    290                 295                 300                 


Gly Gly Ala Tyr Ile Gly Glu Gly Arg Val Glu Val Leu Lys Asn Gly 
305                 310                 315                 320 


Glu Trp Gly Thr Val Cys Asp Asp Lys Trp Asp Leu Val Ser Ala Ser 
                325                 330                 335     


Val Val Cys Arg Glu Leu Gly Phe Gly Ser Ala Lys Glu Ala Val Thr 
            340                 345                 350         


Gly Ser Arg Leu Gly Gln Gly Ile Gly Pro Ile His Leu Asn Glu Ile 
        355                 360                 365             


Gln Cys Thr Gly Asn Glu Lys Ser Ile Ile Asp Cys Lys Phe Asn Ala 
    370                 375                 380                 


Glu Ser Gln Gly Cys Asn His Glu Glu Asp Ala Gly Val Arg Cys Asn 
385                 390                 395                 400 


Thr Pro Ala Met Gly Leu Gln Lys Lys Leu Arg Leu Asn Gly Gly Arg 
                405                 410                 415     


Asn Pro Tyr Glu Gly Arg Val Glu Val Leu Val Glu Arg Asn Gly Ser 
            420                 425                 430         


Leu Val Trp Gly Met Val Cys Gly Gln Asn Trp Gly Ile Val Glu Ala 
        435                 440                 445             


Met Val Val Cys Arg Gln Leu Gly Leu Gly Phe Ala Ser Asn Ala Phe 
    450                 455                 460                 


Gln Glu Thr Trp Tyr Trp His Gly Asp Val Asn Ser Asn Lys Val Val 
465                 470                 475                 480 


Met Ser Gly Val Lys Cys Ser Gly Thr Glu Leu Ser Leu Ala His Cys 
                485                 490                 495     


Arg His Asp Gly Glu Asp Val Ala Cys Pro Gln Gly Gly Val Gln Tyr 
            500                 505                 510         


Gly Ala Gly Val Ala Cys Ser Glu Thr Ala Pro Asp Leu Val Leu Asn 
        515                 520                 525             


Ala Glu Met Val Gln Gln Thr Thr Tyr Leu Glu Asp Arg Pro Met Phe 
    530                 535                 540                 


Leu Leu Gln Cys Ala Met Glu Glu Asn Cys Leu Ser Ala Ser Ala Ala 
545                 550                 555                 560 


Gln Thr Asp Pro Thr Thr Gly Tyr Arg Arg Leu Leu Arg Phe Ser Ser 
                565                 570                 575     


Gln Ile His Asn Asn Gly Gln Ser Asp Phe Arg Pro Lys Asn Gly Arg 
            580                 585                 590         


His Ala Trp Ile Trp His Asp Cys His Arg His Tyr His Ser Met Glu 
        595                 600                 605             


Val Phe Thr His Tyr Asp Leu Leu Asn Leu Asn Gly Thr Lys Val Ala 
    610                 615                 620                 


Glu Gly His Lys Ala Ser Phe Cys Leu Glu Asp Thr Glu Cys Glu Gly 
625                 630                 635                 640 


Asp Ile Gln Lys Asn Tyr Glu Cys Ala Asn Phe Gly Asp Gln Gly Ile 
                645                 650                 655     


Thr Met Gly Cys Trp Asp Met Tyr Arg His Asp Ile Asp Cys Gln Trp 
            660                 665                 670         


Val Asp Ile Thr Asp Val Pro Pro Gly Asp Tyr Leu Phe Gln Val Val 
        675                 680                 685             


Ile Asn Pro Asn Phe Glu Val Ala Glu Ser Asp Tyr Ser Asn Asn Ile 
    690                 695                 700                 


Met Lys Cys Arg Ser Arg Tyr Asp Gly His Arg Ile Trp Met Tyr Asn 
705                 710                 715                 720 


Cys His Ile Gly Gly Ser Phe Ser Glu Glu Thr Glu Lys Lys Phe Glu 
                725                 730                 735     


His Phe Ser Gly Leu Leu Asn Asn Gln Leu Ser Pro Gln 
            740                 745                 


<210>  3071
<211>  460
<212>  PRT
<213>  Homo Sapiens

<400>  3071

Glu His Ser Glu Asn Val His Ile Ser Gly Val Ser Thr Ala Cys Gly 
1               5                   10                  15      


Glu Thr Pro Glu Gln Ile Arg Ala Pro Ser Gly Ile Ile Thr Ser Pro 
            20                  25                  30          


Gly Trp Pro Ser Glu Tyr Pro Ala Lys Ile Asn Cys Ser Trp Phe Ile 
        35                  40                  45              


Arg Ala Asn Pro Gly Glu Ile Ile Thr Ile Ser Phe Gln Asp Phe Asp 
    50                  55                  60                  


Ile Gln Gly Ser Arg Arg Cys Asn Leu Asp Trp Leu Thr Ile Glu Thr 
65                  70                  75                  80  


Tyr Lys Asn Ile Glu Ser Tyr Arg Ala Cys Gly Ser Thr Ile Pro Pro 
                85                  90                  95      


Pro Tyr Ile Ser Ser Gln Asp His Ile Trp Ile Arg Phe His Ser Asp 
            100                 105                 110         


Asp Asn Ile Ser Arg Lys Gly Phe Arg Leu Ala Tyr Phe Ser Gly Lys 
        115                 120                 125             


Ser Glu Glu Pro Asn Cys Ala Cys Asp Gln Phe Arg Cys Gly Asn Gly 
    130                 135                 140                 


Lys Cys Ile Pro Glu Ala Trp Lys Cys Asn Asn Met Asp Glu Cys Gly 
145                 150                 155                 160 


Asp Ser Ser Asp Glu Glu Ile Cys Ala Lys Glu Ala Asn Pro Pro Thr 
                165                 170                 175     


Ala Ala Ala Phe Gln Pro Cys Ala Tyr Asn Gln Phe Gln Cys Leu Ser 
            180                 185                 190         


Arg Phe Thr Lys Val Tyr Thr Cys Leu Pro Glu Ser Leu Lys Cys Asp 
        195                 200                 205             


Gly Asn Ile Asp Cys Leu Asp Leu Gly Asp Glu Ile Asp Cys Asp Val 
    210                 215                 220                 


Pro Thr Cys Gly Gln Trp Leu Lys Tyr Phe Tyr Gly Thr Phe Asn Ser 
225                 230                 235                 240 


Pro Asn Tyr Pro Asp Phe Tyr Pro Pro Gly Ser Asn Cys Thr Trp Leu 
                245                 250                 255     


Ile Asp Thr Gly Asp His Arg Lys Val Ile Leu Arg Phe Thr Asp Phe 
            260                 265                 270         


Lys Leu Asp Gly Thr Gly Tyr Gly Asp Tyr Val Lys Ile Tyr Asp Gly 
        275                 280                 285             


Leu Glu Glu Asn Pro His Lys Leu Leu Arg Val Leu Thr Ala Phe Asp 
    290                 295                 300                 


Ser His Ala Pro Leu Thr Val Val Ser Ser Ser Gly Gln Ile Arg Val 
305                 310                 315                 320 


His Phe Cys Ala Asp Lys Val Asn Ala Ala Arg Gly Phe Asn Ala Thr 
                325                 330                 335     


Tyr Gln Val Asp Gly Phe Cys Leu Pro Trp Glu Ile Pro Cys Gly Gly 
            340                 345                 350         


Asn Trp Gly Cys Tyr Thr Glu Gln Gln Arg Cys Asp Gly Tyr Trp His 
        355                 360                 365             


Cys Pro Asn Gly Arg Asp Glu Thr Asn Cys Thr Met Cys Gln Lys Glu 
    370                 375                 380                 


Glu Phe Pro Cys Ser Arg Asn Gly Val Cys Tyr Pro Arg Ser Asp Arg 
385                 390                 395                 400 


Cys Asn Tyr Gln Asn His Cys Pro Asn Gly Ser Asp Glu Lys Asn Cys 
                405                 410                 415     


Phe Phe Cys Gln Pro Gly Asn Phe His Cys Lys Asn Asn Arg Cys Val 
            420                 425                 430         


Phe Glu Ser Trp Val Cys Asp Ser Gln Asp Asp Cys Gly Asp Gly Ser 
        435                 440                 445             


Asp Glu Glu Asn Cys Pro Val Ile Val Pro Thr Arg 
    450                 455                 460 


<210>  3072
<211>  56
<212>  PRT
<213>  Homo Sapiens

<400>  3072

Trp Thr Asp Cys Trp Met Val Asn Ala Asp Asp Ser Leu Glu Val Ser 
1               5                   10                  15      


Thr Lys Cys Arg Gly Leu Trp Trp Glu Cys Val Thr Asn Ala Phe Asp 
            20                  25                  30          


Gly Ile Arg Thr Cys Asp Glu Tyr Asp Ser Ile Leu Ala Glu His Pro 
        35                  40                  45              


Leu Lys Leu Val Val Thr Arg Ala 
    50                  55      


<210>  3073
<211>  224
<212>  PRT
<213>  Homo Sapiens

<400>  3073

Ile Ile Asn Gly Glu Asp Cys Ser Pro His Ser Gln Pro Trp Gln Ala 
1               5                   10                  15      


Ala Leu Val Met Glu Asn Glu Leu Phe Cys Ser Gly Val Leu Val His 
            20                  25                  30          


Pro Gln Trp Val Leu Ser Ala Ala His Cys Phe Gln Asn Ser Tyr Thr 
        35                  40                  45              


Ile Gly Leu Gly Leu His Ser Leu Glu Ala Asp Gln Glu Pro Gly Ser 
    50                  55                  60                  


Gln Met Val Glu Ala Ser Leu Ser Val Arg His Pro Glu Tyr Asn Arg 
65                  70                  75                  80  


Pro Leu Leu Ala Asn Asp Leu Met Leu Ile Lys Leu Asp Glu Ser Val 
                85                  90                  95      


Ser Glu Ser Asp Thr Ile Arg Ser Ile Ser Ile Ala Ser Gln Cys Pro 
            100                 105                 110         


Thr Ala Gly Asn Ser Cys Leu Val Ser Gly Trp Gly Leu Leu Ala Asn 
        115                 120                 125             


Gly Arg Met Pro Thr Val Leu Gln Cys Val Asn Val Ser Val Val Ser 
    130                 135                 140                 


Glu Glu Val Cys Ser Lys Leu Tyr Asp Pro Leu Tyr His Pro Ser Met 
145                 150                 155                 160 


Phe Cys Ala Gly Gly Gly Gln Asp Gln Lys Asp Ser Cys Asn Gly Asp 
                165                 170                 175     


Ser Gly Gly Pro Leu Ile Cys Asn Gly Tyr Leu Gln Gly Leu Val Ser 
            180                 185                 190         


Phe Gly Lys Ala Pro Cys Gly Gln Val Gly Val Pro Gly Val Tyr Thr 
        195                 200                 205             


Asn Leu Cys Lys Phe Thr Glu Trp Ile Glu Lys Thr Val Gln Ala Ser 
    210                 215                 220                 


<210>  3074
<211>  434
<212>  PRT
<213>  Homo Sapiens

<400>  3074

Thr Arg Asp Val Arg Glu Pro Pro Ala Leu Lys Tyr Gly Ile Val Leu 
1               5                   10                  15      


Asp Ala Gly Ser Ser His Thr Ser Met Phe Ile Tyr Lys Trp Pro Ala 
            20                  25                  30          


Asp Lys Glu Asn Asp Thr Gly Ile Val Gly Gln His Ser Ser Cys Asp 
        35                  40                  45              


Val Pro Gly Gly Gly Ile Ser Ser Tyr Ala Asp Asn Pro Ser Gly Ala 
    50                  55                  60                  


Ser Gln Ser Leu Val Gly Cys Leu Glu Gln Ala Leu Gln Asp Val Pro 
65                  70                  75                  80  


Lys Glu Arg His Ala Gly Thr Pro Leu Tyr Leu Gly Ala Thr Ala Gly 
                85                  90                  95      


Met Arg Leu Leu Asn Leu Thr Asn Pro Glu Ala Ser Thr Ser Val Leu 
            100                 105                 110         


Met Ala Val Thr His Thr Leu Thr Gln Tyr Pro Phe Asp Phe Arg Gly 
        115                 120                 125             


Ala Arg Ile Leu Ser Gly Gln Glu Glu Gly Val Phe Gly Trp Val Thr 
    130                 135                 140                 


Ala Asn Tyr Leu Leu Glu Asn Phe Ile Lys Tyr Gly Trp Val Gly Arg 
145                 150                 155                 160 


Trp Phe Arg Pro Arg Lys Gly Thr Leu Gly Ala Met Asp Leu Gly Gly 
                165                 170                 175     


Ala Ser Thr Gln Ile Thr Phe Glu Thr Thr Ser Pro Ala Glu Asp Arg 
            180                 185                 190         


Ala Ser Glu Val Gln Leu His Leu Tyr Gly Gln His Tyr Arg Val Tyr 
        195                 200                 205             


Thr His Ser Phe Leu Cys Tyr Gly Arg Asp Gln Val Leu Gln Arg Leu 
    210                 215                 220                 


Leu Ala Ser Ala Leu Gln Thr His Gly Phe His Pro Cys Trp Pro Arg 
225                 230                 235                 240 


Gly Phe Ser Thr Gln Val Leu Leu Gly Asp Val Tyr Gln Ser Pro Cys 
                245                 250                 255     


Thr Met Ala Gln Arg Pro Gln Asn Phe Asn Ser Ser Ala Arg Val Ser 
            260                 265                 270         


Leu Ser Gly Ser Ser Asp Pro His Leu Cys Arg Asp Leu Val Ser Gly 
        275                 280                 285             


Leu Phe Ser Phe Ser Ser Cys Pro Phe Ser Arg Cys Ser Phe Asn Gly 
    290                 295                 300                 


Val Phe Gln Pro Pro Val Ala Gly Asn Phe Val Ala Phe Ser Ala Phe 
305                 310                 315                 320 


Phe Tyr Thr Val Asp Phe Leu Arg Thr Ser Met Gly Leu Pro Val Ala 
                325                 330                 335     


Thr Leu Gln Gln Leu Glu Ala Ala Ala Val Asn Val Cys Asn Gln Thr 
            340                 345                 350         


Trp Ala Gln Leu Gln Ala Arg Val Pro Gly Gln Arg Ala Arg Leu Ala 
        355                 360                 365             


Asp Tyr Cys Ala Gly Ala Met Phe Val Gln Gln Leu Leu Ser Arg Gly 
    370                 375                 380                 


Tyr Gly Phe Asp Glu Arg Ala Phe Gly Gly Val Ile Phe Gln Lys Lys 
385                 390                 395                 400 


Ala Ala Asp Thr Ala Val Gly Trp Ala Leu Gly Tyr Met Leu Asn Leu 
                405                 410                 415     


Thr Asn Leu Ile Pro Ala Asp Pro Pro Gly Leu Arg Lys Gly Thr Asp 
            420                 425                 430         


Phe Ser 
        


<210>  3075
<211>  169
<212>  PRT
<213>  Homo Sapiens

<400>  3075

Arg Gly Gln Thr Glu Glu Ser Met Asn Glu Ser His Pro Arg Lys Cys 
1               5                   10                  15      


Ala Glu Ser Phe Glu Met Trp Asp Asp Arg Asp Ser His Cys Arg Arg 
            20                  25                  30          


Pro Lys Phe Glu Gly His Pro Pro Glu Ser Trp Lys Trp Ile Leu Ala 
        35                  40                  45              


Pro Val Ile Leu Tyr Ile Cys Glu Arg Ile Leu Arg Phe Tyr Arg Ser 
    50                  55                  60                  


Gln Gln Lys Val Val Ile Thr Lys Val Val Met His Pro Ser Lys Val 
65                  70                  75                  80  


Leu Glu Leu Gln Met Asn Lys Arg Gly Phe Ser Met Glu Val Gly Gln 
                85                  90                  95      


Tyr Ile Phe Val Asn Cys Pro Ser Ile Ser Leu Leu Glu Trp His Pro 
            100                 105                 110         


Phe Thr Leu Thr Ser Ala Pro Glu Glu Asp Phe Phe Ser Ile His Ile 
        115                 120                 125             


Arg Ala Ala Gly Asp Trp Thr Glu Asn Leu Ile Arg Ala Phe Glu Gln 
    130                 135                 140                 


Gln Tyr Ser Pro Ile Pro Arg Ile Glu Val Asp Gly Pro Phe Gly Thr 
145                 150                 155                 160 


Ala Ser Glu Asp Val Phe Gln Tyr Glu 
                165                 


<210>  3076
<211>  480
<212>  PRT
<213>  Homo Sapiens

<400>  3076

Ser Pro Val Pro Phe Gly Pro Glu Gly Arg Leu Glu Asp Lys Leu His 
1               5                   10                  15      


Lys Pro Lys Ala Thr Gln Thr Glu Val Lys Pro Ser Val Arg Phe Asn 
            20                  25                  30          


Leu Arg Thr Ser Lys Asp Pro Glu His Glu Gly Cys Tyr Leu Ser Val 
        35                  40                  45              


Gly His Ser Gln Pro Leu Glu Asp Cys Ser Phe Asn Met Thr Ala Lys 
    50                  55                  60                  


Thr Phe Phe Ile Ile His Gly Trp Thr Met Ser Gly Ile Phe Glu Asn 
65                  70                  75                  80  


Trp Leu His Lys Leu Val Ser Ala Leu His Thr Arg Glu Lys Asp Ala 
                85                  90                  95      


Asn Val Val Val Val Asp Trp Leu Pro Leu Ala His Gln Leu Tyr Thr 
            100                 105                 110         


Asp Ala Val Asn Asn Thr Arg Val Val Gly His Ser Ile Ala Arg Met 
        115                 120                 125             


Leu Asp Trp Leu Gln Glu Lys Asp Asp Phe Ser Leu Gly Asn Val His 
    130                 135                 140                 


Leu Ile Gly Tyr Ser Leu Gly Ala His Val Ala Gly Tyr Ala Gly Asn 
145                 150                 155                 160 


Phe Val Lys Gly Thr Val Gly Arg Ile Thr Gly Leu Asp Pro Ala Gly 
                165                 170                 175     


Pro Met Phe Glu Gly Ala Asp Ile His Lys Arg Leu Ser Pro Asp Asp 
            180                 185                 190         


Ala Asp Phe Val Asp Val Leu His Thr Tyr Thr Arg Ser Phe Gly Leu 
        195                 200                 205             


Ser Ile Gly Ile Gln Met Pro Val Gly His Ile Asp Ile Tyr Pro Asn 
    210                 215                 220                 


Gly Gly Asp Phe Gln Pro Gly Cys Gly Leu Asn Asp Val Leu Gly Ser 
225                 230                 235                 240 


Ile Ala Tyr Gly Thr Ile Thr Glu Val Val Lys Cys Glu His Glu Arg 
                245                 250                 255     


Ala Val His Leu Phe Val Asp Ser Leu Val Asn Gln Asp Lys Pro Ser 
            260                 265                 270         


Phe Ala Phe Gln Cys Thr Asp Ser Asn Arg Phe Lys Lys Gly Ile Cys 
        275                 280                 285             


Leu Ser Cys Arg Lys Asn Arg Cys Asn Ser Ile Gly Tyr Asn Ala Lys 
    290                 295                 300                 


Lys Met Arg Asn Lys Arg Asn Ser Lys Met Tyr Leu Lys Thr Arg Ala 
305                 310                 315                 320 


Gly Met Pro Phe Arg Val Tyr His Tyr Gln Met Lys Ile His Val Phe 
                325                 330                 335     


Ser Tyr Lys Asn Met Gly Glu Ile Glu Pro Thr Phe Tyr Val Thr Leu 
            340                 345                 350         


Tyr Gly Thr Asn Ala Asp Ser Gln Thr Leu Pro Leu Glu Ile Val Glu 
        355                 360                 365             


Arg Ile Glu Gln Asn Ala Thr Asn Thr Phe Leu Val Tyr Thr Glu Glu 
    370                 375                 380                 


Asp Leu Gly Asp Leu Leu Lys Ile Gln Leu Thr Trp Glu Gly Ala Ser 
385                 390                 395                 400 


Gln Ser Trp Tyr Asn Leu Trp Lys Glu Phe Arg Ser Tyr Leu Ser Gln 
                405                 410                 415     


Pro Arg Asn Pro Gly Arg Glu Leu Asn Ile Arg Arg Ile Arg Val Lys 
            420                 425                 430         


Ser Gly Glu Thr Gln Arg Lys Leu Thr Phe Cys Thr Glu Asp Pro Glu 
        435                 440                 445             


Asn Thr Ser Ile Ser Pro Gly Gln Glu Leu Trp Phe Arg Lys Cys Arg 
    450                 455                 460                 


Asp Gly Trp Arg Met Lys Asn Glu Thr Ser Pro Thr Val Glu Leu Pro 
465                 470                 475                 480 


<210>  3077
<211>  779
<212>  PRT
<213>  Homo Sapiens

<400>  3077

Trp His Leu Gln Tyr Arg Asp Val Arg Val Gln Lys Val Phe Asn Gly 
1               5                   10                  15      


Tyr Met Arg Ile Thr Asn Glu Asn Phe Val Asp Ala Tyr Glu Asn Ser 
            20                  25                  30          


Asn Ser Thr Glu Phe Val Ser Leu Ala Ser Lys Val Lys Asp Ala Leu 
        35                  40                  45              


Lys Leu Leu Tyr Ser Gly Val Pro Phe Leu Gly Pro Tyr His Lys Glu 
    50                  55                  60                  


Ser Ala Val Thr Ala Phe Ser Glu Gly Ser Val Ile Ala Tyr Tyr Trp 
65                  70                  75                  80  


Ser Glu Phe Ser Ile Pro Gln His Leu Val Glu Glu Ala Glu Arg Val 
                85                  90                  95      


Met Ala Glu Glu Arg Val Val Met Leu Pro Pro Arg Ala Arg Ser Leu 
            100                 105                 110         


Lys Ser Phe Val Val Thr Ser Val Val Ala Phe Pro Thr Asp Ser Lys 
        115                 120                 125             


Thr Val Gln Arg Thr Gln Asp Asn Ser Cys Ser Phe Gly Leu His Ala 
    130                 135                 140                 


Arg Gly Val Glu Leu Met Arg Phe Thr Thr Pro Gly Phe Pro Asp Ser 
145                 150                 155                 160 


Pro Tyr Pro Ala His Ala Arg Cys Gln Trp Ala Leu Arg Gly Asp Ala 
                165                 170                 175     


Asp Ser Val Leu Ser Leu Thr Phe Arg Ser Phe Asp Leu Ala Ser Cys 
            180                 185                 190         


Asp Glu Arg Gly Ser Asp Leu Val Thr Val Tyr Asn Thr Leu Ser Pro 
        195                 200                 205             


Met Glu Pro His Ala Leu Val Gln Leu Cys Gly Thr Tyr Pro Pro Ser 
    210                 215                 220                 


Tyr Asn Leu Thr Phe His Ser Ser Gln Asn Val Leu Leu Ile Thr Leu 
225                 230                 235                 240 


Ile Thr Asn Thr Glu Arg Arg His Pro Gly Phe Glu Ala Thr Phe Phe 
                245                 250                 255     


Gln Leu Pro Arg Met Ser Ser Cys Gly Gly Arg Leu Arg Lys Ala Gln 
            260                 265                 270         


Gly Thr Phe Asn Ser Pro Tyr Tyr Pro Gly His Tyr Pro Pro Asn Ile 
        275                 280                 285             


Asp Cys Thr Trp Asn Ile Glu Val Pro Asn Asn Gln His Val Lys Val 
    290                 295                 300                 


Arg Phe Lys Phe Phe Tyr Leu Leu Glu Pro Gly Val Pro Ala Gly Thr 
305                 310                 315                 320 


Cys Pro Lys Asp Tyr Val Glu Ile Asn Gly Glu Lys Tyr Cys Gly Glu 
                325                 330                 335     


Arg Ser Gln Phe Val Val Thr Ser Asn Ser Asn Lys Ile Thr Val Arg 
            340                 345                 350         


Phe His Ser Asp Gln Ser Tyr Thr Asp Thr Gly Phe Leu Ala Glu Tyr 
        355                 360                 365             


Leu Ser Tyr Asp Ser Ser Asp Pro Cys Pro Gly Gln Phe Thr Cys Arg 
    370                 375                 380                 


Thr Gly Arg Cys Ile Arg Lys Glu Leu Arg Cys Asp Gly Trp Ala Asp 
385                 390                 395                 400 


Cys Thr Asp His Ser Asp Glu Leu Asn Cys Ser Cys Asp Ala Gly His 
                405                 410                 415     


Gln Phe Thr Cys Lys Asn Lys Phe Cys Lys Pro Leu Phe Trp Val Cys 
            420                 425                 430         


Asp Ser Val Asn Asp Cys Gly Asp Asn Ser Asp Glu Gln Gly Cys Ser 
        435                 440                 445             


Cys Pro Ala Gln Thr Phe Arg Cys Ser Asn Gly Lys Cys Leu Ser Lys 
    450                 455                 460                 


Ser Gln Gln Cys Asn Gly Lys Asp Asp Cys Gly Asp Gly Ser Asp Glu 
465                 470                 475                 480 


Ala Ser Cys Pro Lys Val Asn Val Val Thr Cys Thr Lys His Thr Tyr 
                485                 490                 495     


Arg Cys Leu Asn Gly Leu Cys Leu Ser Lys Gly Asn Pro Glu Cys Asp 
            500                 505                 510         


Gly Lys Glu Asp Cys Ser Asp Gly Ser Asp Glu Lys Asp Cys Asp Cys 
        515                 520                 525             


Gly Leu Arg Ser Phe Thr Arg Gln Ala Arg Val Val Gly Gly Thr Asp 
    530                 535                 540                 


Ala Asp Glu Gly Glu Trp Pro Trp Gln Val Ser Leu His Ala Leu Gly 
545                 550                 555                 560 


Gln Gly His Ile Cys Gly Ala Ser Leu Ile Ser Pro Asn Trp Leu Val 
                565                 570                 575     


Ser Ala Ala His Cys Tyr Ile Asp Asp Arg Gly Phe Arg Tyr Ser Asp 
            580                 585                 590         


Pro Thr Gln Trp Thr Ala Phe Leu Gly Leu His Asp Gln Ser Gln Arg 
        595                 600                 605             


Ser Ala Pro Gly Val Gln Glu Arg Arg Leu Lys Arg Ile Ile Ser His 
    610                 615                 620                 


Pro Phe Phe Asn Asp Phe Thr Phe Asp Tyr Asp Ile Ala Leu Leu Glu 
625                 630                 635                 640 


Leu Glu Lys Pro Ala Glu Tyr Ser Ser Met Val Arg Pro Ile Cys Leu 
                645                 650                 655     


Pro Asp Ala Ser His Val Phe Pro Ala Gly Lys Ala Ile Trp Val Thr 
            660                 665                 670         


Gly Trp Gly His Thr Gln Tyr Gly Gly Thr Gly Ala Leu Ile Leu Gln 
        675                 680                 685             


Lys Gly Glu Ile Arg Val Ile Asn Gln Thr Thr Cys Glu Asn Leu Leu 
    690                 695                 700                 


Pro Gln Gln Ile Thr Pro Arg Met Met Cys Val Gly Phe Leu Ser Gly 
705                 710                 715                 720 


Gly Val Asp Ser Cys Gln Gly Asp Ser Gly Gly Pro Leu Ser Ser Val 
                725                 730                 735     


Glu Ala Asp Gly Arg Ile Phe Gln Ala Gly Val Val Ser Trp Gly Asp 
            740                 745                 750         


Gly Cys Ala Gln Arg Asn Lys Pro Gly Val Tyr Thr Arg Leu Pro Leu 
        755                 760                 765             


Phe Arg Asp Trp Ile Lys Glu Asn Thr Gly Val 
    770                 775                 


<210>  3078
<211>  219
<212>  PRT
<213>  Homo Sapiens

<400>  3078

Leu Val Gln Gly Ser Leu Arg Ala Glu Glu Leu Ser Ile Gln Val Ser 
1               5                   10                  15      


Cys Arg Ile Met Gly Ile Thr Leu Val Ser Lys Lys Ala Asn Gln Gln 
            20                  25                  30          


Leu Asn Phe Thr Glu Ala Lys Glu Ala Cys Arg Leu Leu Gly Leu Ser 
        35                  40                  45              


Leu Ala Gly Lys Asp Gln Val Glu Thr Ala Leu Lys Ala Ser Phe Glu 
    50                  55                  60                  


Thr Cys Ser Tyr Gly Trp Val Gly Asp Gly Phe Val Val Ile Ser Arg 
65                  70                  75                  80  


Ile Ser Pro Asn Pro Lys Cys Gly Lys Asn Gly Val Gly Val Leu Ile 
                85                  90                  95      


Arg Lys Val Pro Val Ser Arg Gln Phe Ala Ala Tyr Cys Tyr Asn Ser 
            100                 105                 110         


Ser Asp Thr Trp Thr Asn Ser Cys Ile Pro Glu Ile Ile Thr Thr Lys 
        115                 120                 125             


Asp Pro Ile Phe Asn Thr Gln Thr Ala Thr Gln Thr Thr Glu Phe Ile 
    130                 135                 140                 


Val Ser Asp Ser Thr Tyr Ser Val Ala Ser Pro Tyr Ser Thr Ile Pro 
145                 150                 155                 160 


Ala Pro Thr Thr Thr Pro Pro Ala Pro Ala Ser Thr Ser Ile Pro Arg 
                165                 170                 175     


Arg Lys Lys Leu Ile Cys Val Thr Glu Val Phe Met Glu Thr Ser Thr 
            180                 185                 190         


Met Ser Thr Glu Thr Glu Pro Phe Val Glu Asn Lys Ala Ala Phe Lys 
        195                 200                 205             


Asn Glu Ala Ala Gly Phe Gly Gly Val Pro Thr 
    210                 215                 


<210>  3079
<211>  453
<212>  PRT
<213>  Homo Sapiens

<400>  3079

Ala Pro Glu Leu Ala Pro Ala Pro Phe Thr Leu Pro Leu Arg Val Ala 
1               5                   10                  15      


Ala Ala Thr Asn Arg Val Val Ala Pro Thr Pro Gly Pro Gly Thr Pro 
            20                  25                  30          


Ala Glu Arg His Ala Asp Gly Leu Ala Leu Ala Leu Glu Pro Ala Leu 
        35                  40                  45              


Ala Ser Pro Ala Gly Ala Ala Asn Phe Leu Ala Met Val Asp Asn Leu 
    50                  55                  60                  


Gln Gly Asp Ser Gly Arg Gly Tyr Tyr Leu Glu Met Leu Ile Gly Thr 
65                  70                  75                  80  


Pro Pro Gln Lys Leu Gln Ile Leu Val Asp Thr Gly Ser Ser Asn Phe 
                85                  90                  95      


Ala Val Ala Gly Thr Pro His Ser Tyr Ile Asp Thr Tyr Phe Asp Thr 
            100                 105                 110         


Glu Arg Ser Ser Thr Tyr Arg Ser Lys Gly Phe Asp Val Thr Val Lys 
        115                 120                 125             


Tyr Thr Gln Gly Ser Trp Thr Gly Phe Val Gly Glu Asp Leu Val Thr 
    130                 135                 140                 


Ile Pro Lys Gly Phe Asn Thr Ser Phe Leu Val Asn Ile Ala Thr Ile 
145                 150                 155                 160 


Phe Glu Ser Glu Asn Phe Phe Leu Pro Gly Ile Lys Trp Asn Gly Ile 
                165                 170                 175     


Leu Gly Leu Ala Tyr Ala Thr Leu Ala Lys Pro Ser Ser Ser Leu Glu 
            180                 185                 190         


Thr Phe Phe Asp Ser Leu Val Thr Gln Ala Asn Ile Pro Asn Val Phe 
        195                 200                 205             


Ser Met Gln Met Cys Gly Ala Gly Leu Pro Val Ala Gly Ser Gly Thr 
    210                 215                 220                 


Asn Gly Gly Ser Leu Val Leu Gly Gly Ile Glu Pro Ser Leu Tyr Lys 
225                 230                 235                 240 


Gly Asp Ile Trp Tyr Thr Pro Ile Lys Glu Glu Trp Tyr Tyr Gln Ile 
                245                 250                 255     


Glu Ile Leu Lys Leu Glu Ile Gly Gly Gln Ser Leu Asn Leu Asp Cys 
            260                 265                 270         


Arg Glu Tyr Asn Ala Asp Lys Ala Ile Val Asp Ser Gly Thr Thr Leu 
        275                 280                 285             


Leu Arg Leu Pro Gln Lys Val Phe Asp Ala Val Val Glu Ala Val Ala 
    290                 295                 300                 


Arg Ala Ser Leu Ile Pro Glu Phe Ser Asp Gly Phe Trp Thr Gly Ser 
305                 310                 315                 320 


Gln Leu Ala Cys Trp Thr Asn Ser Glu Thr Pro Trp Ser Tyr Phe Pro 
                325                 330                 335     


Lys Ile Ser Ile Tyr Leu Arg Asp Glu Asn Ser Ser Arg Ser Phe Arg 
            340                 345                 350         


Ile Thr Ile Leu Pro Gln Leu Tyr Ile Gln Pro Met Met Gly Ala Gly 
        355                 360                 365             


Leu Asn Tyr Glu Cys Tyr Arg Phe Gly Ile Ser Pro Ser Thr Asn Ala 
    370                 375                 380                 


Leu Val Ile Gly Ala Thr Val Met Glu Gly Phe Tyr Val Ile Phe Asp 
385                 390                 395                 400 


Arg Ala Gln Lys Arg Val Gly Phe Ala Ala Ser Pro Cys Ala Glu Ile 
                405                 410                 415     


Ala Gly Ala Ala Val Ser Glu Ile Ser Gly Pro Phe Ser Thr Glu Asp 
            420                 425                 430         


Val Ala Ser Asn Cys Val Pro Ala Gln Ser Leu Ser Glu Pro Ile Leu 
        435                 440                 445             


Trp Ile Val Ser Tyr 
    450             


<210>  3080
<211>  506
<212>  PRT
<213>  Homo Sapiens

<400>  3080

Asp Val Lys Ala Arg Ser Cys Gly Glu Val Arg Gln Ala Tyr Gly Ala 
1               5                   10                  15      


Lys Gly Phe Ser Leu Ala Asp Ile Pro Tyr Gln Glu Ile Ala Gly Glu 
            20                  25                  30          


His Leu Arg Ile Cys Pro Gln Glu Tyr Thr Cys Cys Thr Thr Glu Met 
        35                  40                  45              


Glu Asp Lys Leu Ser Gln Gln Ser Lys Leu Glu Phe Glu Asn Leu Val 
    50                  55                  60                  


Glu Glu Thr Ser His Phe Val Arg Thr Thr Phe Val Ser Arg His Lys 
65                  70                  75                  80  


Lys Phe Asp Glu Phe Phe Arg Glu Leu Leu Glu Asn Ala Glu Lys Ser 
                85                  90                  95      


Leu Asn Asp Met Phe Val Arg Thr Tyr Gly Met Leu Tyr Met Gln Asn 
            100                 105                 110         


Ser Glu Val Phe Gln Asp Leu Phe Thr Glu Leu Lys Arg Tyr Tyr Thr 
        115                 120                 125             


Gly Gly Asn Val Asn Leu Glu Glu Met Leu Asn Asp Phe Trp Ala Arg 
    130                 135                 140                 


Leu Leu Glu Arg Met Phe Gln Leu Ile Asn Pro Gln Tyr His Phe Ser 
145                 150                 155                 160 


Glu Asp Tyr Leu Glu Cys Val Ser Lys Tyr Thr Asp Gln Leu Lys Pro 
                165                 170                 175     


Phe Gly Asp Val Pro Arg Lys Leu Lys Ile Gln Val Thr Arg Ala Phe 
            180                 185                 190         


Ile Ala Ala Arg Thr Phe Val Gln Gly Leu Thr Val Gly Arg Glu Val 
        195                 200                 205             


Ala Asn Arg Val Ser Lys Val Ser Pro Thr Pro Gly Cys Ile Arg Ala 
    210                 215                 220                 


Leu Met Lys Met Leu Tyr Cys Pro Tyr Cys Arg Gly Leu Pro Thr Val 
225                 230                 235                 240 


Arg Pro Cys Asn Asn Tyr Cys Leu Asn Val Met Lys Gly Cys Leu Ala 
                245                 250                 255     


Asn Gln Ala Asp Leu Asp Thr Glu Trp Asn Leu Phe Ile Asp Ala Met 
            260                 265                 270         


Leu Leu Val Ala Glu Arg Leu Glu Gly Pro Phe Asn Ile Glu Ser Val 
        275                 280                 285             


Met Asp Pro Ile Asp Val Lys Ile Ser Glu Ala Ile Met Asn Met Gln 
    290                 295                 300                 


Glu Asn Ser Met Gln Val Ser Ala Lys Val Phe Gln Gly Cys Gly Gln 
305                 310                 315                 320 


Pro Lys Pro Ala Pro Ala Leu Arg Ser Ala Arg Ser Ala Pro Glu Asn 
                325                 330                 335     


Phe Asn Thr Arg Phe Arg Pro Tyr Asn Pro Glu Glu Arg Pro Thr Thr 
            340                 345                 350         


Ala Ala Gly Thr Ser Leu Asp Arg Leu Val Thr Asp Ile Lys Glu Lys 
        355                 360                 365             


Leu Lys Leu Ser Lys Lys Val Trp Ser Ala Leu Pro Tyr Thr Ile Cys 
    370                 375                 380                 


Lys Asp Glu Ser Val Thr Ala Gly Thr Ser Asn Glu Glu Glu Cys Trp 
385                 390                 395                 400 


Asn Gly His Ser Lys Ala Arg Tyr Leu Pro Glu Ile Met Asn Asp Gly 
                405                 410                 415     


Leu Thr Asn Gln Ile Asn Asn Pro Glu Val Asp Val Asp Ile Thr Arg 
            420                 425                 430         


Pro Asp Thr Phe Ile Arg Gln Gln Ile Met Ala Leu Arg Val Met Thr 
        435                 440                 445             


Asn Lys Leu Lys Asn Ala Tyr Asn Gly Asn Asp Val Asn Phe Gln Asp 
    450                 455                 460                 


Thr Ser Asp Glu Ser Ser Gly Ser Gly Ser Gly Ser Gly Cys Met Asp 
465                 470                 475                 480 


Asp Val Cys Pro Thr Glu Phe Glu Phe Val Thr Thr Glu Ala Pro Ala 
                485                 490                 495     


Val Asp Pro Asp Arg Arg Glu Val Asp Ser 
            500                 505     


<210>  3081
<211>  428
<212>  PRT
<213>  Homo Sapiens

<400>  3081

Asp Val Ala Lys Ala Ile Ile Asn Leu Ala Val Tyr Gly Lys Ala Gln 
1               5                   10                  15      


Asn Arg Ser Tyr Glu Arg Leu Ala Leu Leu Val Asp Thr Val Gly Pro 
            20                  25                  30          


Arg Leu Ser Gly Ser Lys Asn Leu Glu Lys Ala Ile Gln Ile Met Tyr 
        35                  40                  45              


Gln Asn Leu Gln Gln Asp Gly Leu Glu Lys Val His Leu Glu Pro Val 
    50                  55                  60                  


Arg Ile Pro His Trp Glu Arg Gly Glu Glu Ser Ala Val Met Leu Glu 
65                  70                  75                  80  


Pro Arg Ile His Lys Ile Ala Ile Leu Gly Leu Gly Ser Ser Ile Gly 
                85                  90                  95      


Thr Pro Pro Glu Gly Ile Thr Ala Glu Val Leu Val Val Thr Ser Phe 
            100                 105                 110         


Asp Glu Leu Gln Arg Arg Ala Ser Glu Ala Arg Gly Lys Ile Val Val 
        115                 120                 125             


Tyr Asn Gln Pro Tyr Ile Asn Tyr Ser Arg Thr Val Gln Tyr Arg Thr 
    130                 135                 140                 


Gln Gly Ala Val Glu Ala Ala Lys Val Gly Ala Leu Ala Ser Leu Ile 
145                 150                 155                 160 


Arg Ser Val Ala Ser Phe Ser Ile Tyr Ser Pro His Thr Gly Ile Gln 
                165                 170                 175     


Glu Tyr Gln Asp Gly Val Pro Lys Ile Pro Thr Ala Cys Ile Thr Val 
            180                 185                 190         


Glu Asp Ala Glu Met Met Ser Arg Met Ala Ser His Gly Ile Lys Ile 
        195                 200                 205             


Val Ile Gln Leu Lys Met Gly Ala Lys Thr Tyr Pro Asp Thr Asp Ser 
    210                 215                 220                 


Phe Asn Thr Val Ala Glu Ile Thr Gly Ser Lys Tyr Pro Glu Gln Val 
225                 230                 235                 240 


Val Leu Val Ser Gly His Leu Asp Ser Trp Asp Val Gly Gln Gly Ala 
                245                 250                 255     


Met Asp Asp Gly Gly Gly Ala Phe Ile Ser Trp Glu Ala Leu Ser Leu 
            260                 265                 270         


Ile Lys Asp Leu Gly Leu Arg Pro Lys Arg Thr Leu Arg Leu Val Leu 
        275                 280                 285             


Trp Thr Ala Glu Glu Gln Gly Gly Val Gly Ala Phe Gln Tyr Tyr Gln 
    290                 295                 300                 


Leu His Lys Val Asn Ile Ser Asn Tyr Ser Leu Val Met Glu Ser Asp 
305                 310                 315                 320 


Ala Gly Thr Phe Leu Pro Thr Gly Leu Gln Phe Thr Gly Ser Glu Lys 
                325                 330                 335     


Ala Arg Ala Ile Met Glu Glu Val Met Ser Leu Leu Gln Pro Leu Asn 
            340                 345                 350         


Ile Thr Gln Val Leu Ser His Gly Glu Gly Thr Asp Ile Asn Phe Trp 
        355                 360                 365             


Ile Gln Ala Gly Val Pro Gly Ala Ser Leu Leu Asp Asp Leu Tyr Lys 
    370                 375                 380                 


Tyr Phe Phe Phe His His Ser His Gly Asp Thr Met Thr Val Met Asp 
385                 390                 395                 400 


Pro Lys Gln Met Asn Val Ala Ala Ala Val Trp Ala Val Val Ser Tyr 
                405                 410                 415     


Val Val Ala Asp Met Glu Glu Met Leu Pro Arg Ser 
            420                 425             


<210>  3082
<211>  199
<212>  PRT
<213>  Homo Sapiens

<400>  3082

Gln Arg Gln Lys Lys Glu Glu Ser Thr Glu Glu Val Lys Ile Glu Val 
1               5                   10                  15      


Leu His Arg Pro Glu Asn Cys Ser Lys Thr Ser Lys Lys Gly Asp Leu 
            20                  25                  30          


Leu Asn Ala His Tyr Asp Gly Tyr Leu Ala Lys Asp Gly Ser Lys Phe 
        35                  40                  45              


Tyr Cys Ser Arg Thr Gln Asn Glu Gly His Pro Lys Trp Phe Val Leu 
    50                  55                  60                  


Gly Val Gly Gln Val Ile Lys Gly Leu Asp Ile Ala Met Thr Asp Met 
65                  70                  75                  80  


Cys Pro Gly Glu Lys Arg Lys Val Val Ile Pro Pro Ser Phe Ala Tyr 
                85                  90                  95      


Gly Lys Glu Gly Tyr Ala Glu Gly Lys Ile Pro Pro Asp Ala Thr Leu 
            100                 105                 110         


Ile Phe Glu Ile Glu Leu Tyr Ala Val Thr Lys Gly Pro Arg Ser Ile 
        115                 120                 125             


Glu Thr Phe Lys Gln Ile Asp Met Asp Asn Asp Arg Gln Leu Ser Lys 
    130                 135                 140                 


Ala Glu Ile Asn Leu Tyr Leu Gln Arg Glu Phe Glu Lys Asp Glu Lys 
145                 150                 155                 160 


Pro Arg Asp Lys Ser Tyr Gln Asp Ala Val Leu Glu Asp Ile Phe Lys 
                165                 170                 175     


Lys Asn Asp His Asp Gly Asp Gly Phe Ile Ser Pro Lys Glu Tyr Asn 
            180                 185                 190         


Val Tyr Gln His Asp Glu Leu 
        195                 


<210>  3083
<211>  127
<212>  PRT
<213>  Homo Sapiens

<400>  3083

Thr Leu Leu Arg Ser Tyr Met Gln Ser Val Trp Thr Glu Glu Ser Gln 
1               5                   10                  15      


Cys Thr Leu Leu Asn Ala Ser Ile Thr Glu Thr Phe Asn Cys Ser Phe 
            20                  25                  30          


Ser Cys Gly Pro Asp Cys Trp Lys Leu Ser Gln Tyr Pro Cys Leu Gln 
        35                  40                  45              


Val Tyr Val Asn Leu Thr Ser Ser Gly Glu Lys Leu Leu Leu Tyr His 
    50                  55                  60                  


Thr Glu Glu Thr Ile Lys Ile Asn Gln Lys Cys Ser Tyr Ile Pro Lys 
65                  70                  75                  80  


Cys Gly Lys Asn Phe Glu Glu Ser Met Ser Leu Val Asn Val Val Met 
                85                  90                  95      


Glu Asn Phe Arg Lys Tyr Gln His Phe Ser Cys Tyr Ser Asp Pro Glu 
            100                 105                 110         


Gly Asn Gln Lys Ser Val Ile Leu Thr Lys Leu Tyr Ser Ser Asn 
        115                 120                 125         


<210>  3084
<211>  62
<212>  PRT
<213>  Homo Sapiens

<400>  3084

Thr Ser Cys Val Gly Phe Phe Met Pro Tyr Trp Leu Trp Gly Ser Gln 
1               5                   10                  15      


Leu Gly Lys Pro Val Ser Phe Gly Thr Phe Arg Arg Cys Ser Tyr Pro 
            20                  25                  30          


Val His Asp Glu Ser Arg Gln Met Met Val Met Val Glu Glu Cys Gly 
        35                  40                  45              


Arg Tyr Ala Ser Phe Gln Gly Ile Pro Ser Ala Glu Trp Arg 
    50                  55                  60          


<210>  3085
<211>  314
<212>  PRT
<213>  Homo Sapiens

<400>  3085

Glu Thr Asn Leu Glu Gln Leu Trp Val Glu Val Gly Ser Arg Val Ser 
1               5                   10                  15      


Gln Glu Leu His Tyr Thr Lys Glu Lys Leu Gly Glu Glu Ala Ala Tyr 
            20                  25                  30          


Thr Ser Gln Met Leu Ile Gln Thr Ala Arg Gln Glu Gly Glu Asn Ile 
        35                  40                  45              


Leu Thr Pro Glu Ala Leu Gly Leu His Leu Gln Ala Ala Leu Thr Ala 
    50                  55                  60                  


Ser Lys Val Gln Val Ser Leu Tyr Gly Lys Ser Trp Asp Leu Asn Lys 
65                  70                  75                  80  


Ile Cys Tyr Lys Ser Gly Val Pro Leu Ile Glu Asn Gly Met Ile Glu 
                85                  90                  95      


Arg Met Ile Glu Lys Leu Phe Pro Cys Val Ile Leu Thr Pro Leu Asp 
            100                 105                 110         


Cys Phe Trp Glu Gly Ala Lys Leu Gln Gly Gly Ser Ala Tyr Leu Pro 
        115                 120                 125             


Gly Arg Pro Asp Ile Gln Trp Thr Asn Leu Asp Pro Glu Gln Leu Leu 
    130                 135                 140                 


Glu Glu Leu Gly Pro Phe Ala Ser Leu Glu Gly Phe Arg Glu Leu Leu 
145                 150                 155                 160 


Asp Lys Ala Gln Val Gly Gln Ala Tyr Val Gly Arg Pro Cys Leu His 
                165                 170                 175     


Pro Asp Asp Leu His Cys Pro Pro Ser Ala Pro Asn His His Ser Arg 
            180                 185                 190         


Gln Ala Pro Asn Val Ala His Glu Leu Ser Gly Gly Cys His Gly Phe 
        195                 200                 205             


Ser His Lys Phe Met His Trp Gln Glu Glu Leu Leu Leu Gly Gly Met 
    210                 215                 220                 


Ala Arg Asp Pro Gln Gly Glu Leu Leu Arg Ala Glu Ala Leu Gln Ser 
225                 230                 235                 240 


Thr Phe Leu Leu Met Ser Pro Arg Gln Leu Tyr Glu His Phe Arg Gly 
                245                 250                 255     


Asp Tyr Gln Thr His Asp Ile Gly Trp Ser Glu Glu Gln Ala Ser Thr 
            260                 265                 270         


Val Leu Gln Ala Trp Gln Arg Arg Phe Val Gln Leu Ala Gln Glu Ala 
        275                 280                 285             


Leu Pro Glu Asn Ala Ser Gln Gln Ile His Ala Phe Ser Ser Thr Thr 
    290                 295                 300                 


Leu Asp Asp Ile Leu His Ala Phe Ser Glu 
305                 310                 


<210>  3086
<211>  281
<212>  PRT
<213>  Homo Sapiens

<400>  3086

Gly Val Glu Val Ser Ala Gly Ser Pro Pro Ile Arg Asn Val Thr Val 
1               5                   10                  15      


Ala Tyr Lys Phe His Met Gly Leu Tyr Gly Glu Thr Gly Arg Leu Phe 
            20                  25                  30          


Thr Glu Ser Cys Ser Ile Ser Pro Lys Leu Arg Ser Ile Ala Val Tyr 
        35                  40                  45              


Tyr Asp Asn Pro His Met Val Pro Pro Asp Lys Cys Arg Cys Ala Val 
    50                  55                  60                  


Gly Ser Ile Leu Ser Glu Gly Glu Glu Ser Pro Ser Pro Glu Leu Ile 
65                  70                  75                  80  


Asp Leu Tyr Gln Lys Phe Gly Phe Lys Val Phe Ser Phe Pro Ala Pro 
                85                  90                  95      


Ser His Val Val Thr Ala Thr Phe Pro Tyr Thr Thr Ile Leu Ser Ile 
            100                 105                 110         


Trp Leu Ala Thr Arg Arg Val His Pro Ala Leu Asp Thr Tyr Ile Lys 
        115                 120                 125             


Glu Arg Lys Leu Cys Ala Tyr Pro Arg Leu Glu Ile Tyr Gln Glu Asp 
    130                 135                 140                 


Gln Ile His Phe Met Cys Pro Leu Ala Arg Gln Gly Asp Phe Tyr Val 
145                 150                 155                 160 


Pro Glu Met Lys Glu Thr Glu Trp Lys Trp Arg Gly Leu Val Glu Ala 
                165                 170                 175     


Ile Asp Thr Gln Val Asp Gly Thr Gly Ala Asp Thr Met Ser Asp Thr 
            180                 185                 190         


Ser Ser Val Ser Leu Glu Val Ser Pro Gly Ser Arg Glu Thr Ser Ala 
        195                 200                 205             


Ala Thr Leu Ser Pro Gly Ala Ser Ser Arg Gly Trp Asp Asp Gly Asp 
    210                 215                 220                 


Thr Arg Ser Glu His Ser Tyr Ser Glu Ser Gly Ala Ser Gly Ser Ser 
225                 230                 235                 240 


Phe Glu Glu Leu Asp Leu Glu Gly Glu Gly Pro Leu Gly Glu Ser Arg 
                245                 250                 255     


Leu Asp Pro Gly Thr Glu Pro Leu Gly Thr Thr Lys Trp Leu Trp Glu 
            260                 265                 270         


Pro Thr Ala Pro Glu Lys Gly Lys Glu 
        275                 280     


<210>  3087
<211>  112
<212>  PRT
<213>  Homo Sapiens

<400>  3087

Phe Phe Ile Leu Cys Glu Asn Lys Ser Val Ala Gly Leu Thr Met Thr 
1               5                   10                  15      


Tyr Asp Gly Asn Asn Pro Val Thr Ser His Arg Asp Val Pro Leu Ser 
            20                  25                  30          


Tyr Cys Asn Ser Asp Cys Asn Cys Asp Glu Ser Gln Trp Glu Pro Val 
        35                  40                  45              


Cys Gly Asn Asn Gly Ile Thr Tyr Ile Ser Pro Cys Leu Ala Gly Cys 
    50                  55                  60                  


Lys Ser Ser Ser Gly Asn Lys Lys Pro Ile Val Phe Tyr Asn Cys Ser 
65                  70                  75                  80  


Cys Leu Glu Val Thr Gly Leu Gln Asn Arg Asn Tyr Ser Ala His Leu 
                85                  90                  95      


Gly Glu Cys Pro Arg Asp Asp Ala Cys Thr Arg Lys Phe Tyr Phe Phe 
            100                 105                 110         


<210>  3088
<211>  247
<212>  PRT
<213>  Homo Sapiens

<400>  3088

Ile Val Gly Gly Glu Asp Ala Glu Leu Gly Arg Trp Pro Trp Gln Gly 
1               5                   10                  15      


Ser Leu Arg Leu Trp Asp Ser His Val Cys Gly Val Ser Leu Leu Ser 
            20                  25                  30          


His Arg Trp Ala Leu Thr Ala Ala His Cys Phe Glu Thr Tyr Ser Asp 
        35                  40                  45              


Leu Ser Asp Pro Ser Gly Trp Met Val Gln Phe Gly Gln Leu Thr Ser 
    50                  55                  60                  


Met Pro Ser Phe Trp Ser Leu Gln Ala Tyr Tyr Thr Arg Tyr Phe Val 
65                  70                  75                  80  


Ser Asn Ile Tyr Leu Ser Pro Arg Tyr Leu Gly Asn Ser Pro Tyr Asp 
                85                  90                  95      


Ile Ala Leu Val Lys Leu Ser Ala Pro Val Thr Tyr Thr Lys His Ile 
            100                 105                 110         


Gln Pro Ile Cys Leu Gln Ala Ser Thr Phe Glu Phe Glu Asn Arg Thr 
        115                 120                 125             


Asp Cys Trp Val Thr Gly Trp Gly Tyr Ile Lys Glu Asp Glu Ala Leu 
    130                 135                 140                 


Pro Ser Pro His Thr Leu Gln Glu Val Gln Val Ala Ile Ile Asn Asn 
145                 150                 155                 160 


Ser Met Cys Asn His Leu Phe Leu Lys Tyr Ser Phe Arg Lys Asp Ile 
                165                 170                 175     


Phe Gly Asp Met Val Cys Ala Gly Asn Ala Gln Gly Gly Lys Asp Ala 
            180                 185                 190         


Cys Phe Gly Asp Ser Gly Gly Pro Leu Ala Cys Asn Lys Asn Gly Leu 
        195                 200                 205             


Trp Tyr Gln Ile Gly Val Val Ser Trp Gly Val Gly Cys Gly Arg Pro 
    210                 215                 220                 


Asn Arg Pro Gly Val Tyr Thr Asn Ile Ser His His Phe Glu Trp Ile 
225                 230                 235                 240 


Gln Lys Leu Met Ala Gln Ser 
                245         


<210>  3089
<211>  608
<212>  PRT
<213>  Homo Sapiens

<400>  3089

Met Glu Arg Phe Arg Leu Glu Lys Lys Leu Pro Gly Pro Asp Glu Glu 
1               5                   10                  15      


Ala Val Val Asp Leu Gly Lys Thr Ser Ser Thr Val Asn Thr Lys Phe 
            20                  25                  30          


Glu Lys Glu Glu Leu Glu Ser His Arg Ala Val Tyr Ile Gly Val His 
        35                  40                  45              


Val Pro Phe Ser Lys Glu Ser Arg Arg Arg His Arg His Arg Gly His 
    50                  55                  60                  


Lys His His His Arg Arg Arg Lys Asp Lys Glu Ser Asp Lys Glu Asp 
65                  70                  75                  80  


Gly Arg Glu Ser Pro Ser Tyr Asp Thr Pro Ser Gln Arg Val Gln Phe 
                85                  90                  95      


Ile Leu Gly Thr Glu Asp Asp Asp Glu Glu His Ile Pro His Asp Leu 
            100                 105                 110         


Phe Thr Glu Met Asp Glu Leu Cys Tyr Arg Asp Gly Glu Glu Tyr Glu 
        115                 120                 125             


Trp Lys Glu Thr Ala Arg Trp Leu Lys Phe Glu Glu Asp Val Glu Asp 
    130                 135                 140                 


Gly Gly Asp Arg Trp Ser Lys Pro Tyr Val Ala Thr Leu Ser Leu His 
145                 150                 155                 160 


Ser Leu Phe Glu Leu Arg Ser Cys Ile Leu Asn Gly Thr Val Met Leu 
                165                 170                 175     


Asp Met Arg Ala Ser Thr Leu Asp Glu Ile Ala Asp Met Val Leu Asp 
            180                 185                 190         


Asn Met Ile Ala Ser Gly Gln Leu Asp Glu Ser Ile Arg Glu Asn Val 
        195                 200                 205             


Arg Glu Ala Leu Leu Lys Arg His His His Gln Asn Glu Lys Arg Phe 
    210                 215                 220                 


Thr Ser Arg Ile Pro Leu Val Arg Ser Phe Ala Asp Ile Gly Lys Lys 
225                 230                 235                 240 


His Ser Asp Pro His Leu Leu Glu Arg Asn Gly Glu Gly Leu Ser Ala 
                245                 250                 255     


Ser Arg His Ser Leu Arg Thr Gly Leu Ser Ala Ser Asn Leu Ser Leu 
            260                 265                 270         


Arg Gly Glu Ser Pro Leu Ser Leu Leu Leu Gly His Leu Leu Pro Ser 
        275                 280                 285             


Ser Arg Ala Gly Thr Pro Ala Gly Ser Arg Cys Thr Thr Pro Val Pro 
    290                 295                 300                 


Thr Pro Gln Asn Ser Pro Pro Ser Ser Pro Ser Ile Ser Arg Leu Thr 
305                 310                 315                 320 


Ser Arg Ser Ser Gln Glu Ser Gln Arg Gln Ala Pro Glu Leu Leu Val 
                325                 330                 335     


Ser Pro Ala Ser Asp Asp Ile Pro Thr Val Val Ile His Pro Pro Glu 
            340                 345                 350         


Glu Asp Leu Glu Ala Ala Leu Lys Gly Glu Glu Gln Lys Asn Glu Glu 
        355                 360                 365             


Asn Val Asp Leu Thr Pro Gly Ile Leu Ala Ser Pro Gln Ser Ala Pro 
    370                 375                 380                 


Gly Asn Leu Asp Asn Ser Lys Ser Gly Glu Ile Lys Gly Asn Gly Ser 
385                 390                 395                 400 


Gly Gly Ser Arg Glu Asn Ser Thr Val Asp Phe Ser Lys Val Asp Met 
                405                 410                 415     


Asn Phe Met Arg Lys Ile Pro Thr Gly Ala Glu Ala Ser Asn Val Leu 
            420                 425                 430         


Val Gly Glu Val Asp Phe Leu Glu Arg Pro Ile Ile Ala Phe Val Arg 
        435                 440                 445             


Leu Ala Pro Ala Val Leu Leu Thr Gly Leu Thr Glu Val Pro Val Pro 
    450                 455                 460                 


Thr Arg Phe Leu Phe Leu Leu Leu Gly Pro Ala Gly Lys Ala Pro Gln 
465                 470                 475                 480 


Tyr His Glu Ile Gly Arg Ser Ile Ala Thr Leu Met Thr Asp Glu Ile 
                485                 490                 495     


Phe His Asp Val Ala Tyr Lys Ala Lys Asp Arg Asn Asp Leu Leu Ser 
            500                 505                 510         


Gly Ile Asp Glu Phe Leu Asp Gln Val Thr Val Leu Pro Pro Gly Glu 
        515                 520                 525             


Trp Asp Pro Ser Ile Arg Ile Glu Pro Pro Lys Ser Val Pro Ser Gln 
    530                 535                 540                 


Glu Lys Arg Lys Ile Pro Val Phe His Asn Gly Ser Thr Pro Thr Leu 
545                 550                 555                 560 


Gly Glu Thr Pro Lys Glu Ala Ala His His Ala Gly Pro Glu Leu Gln 
                565                 570                 575     


Arg Thr Gly Arg Leu Phe Gly Gly Leu Ile Leu Asp Ile Lys Arg Lys 
            580                 585                 590         


Ala Pro Phe Phe Leu Ser Asp Phe Lys Asp Ala Leu Ser Leu Gln Cys 
        595                 600                 605             


<210>  3090
<211>  207
<212>  PRT
<213>  Homo Sapiens

<400>  3090

Asp Gly Ser Glu Pro Ala Ala Gly Ala Gly Arg Gly Gly Ala Arg Ala 
1               5                   10                  15      


Val Arg Val Asp Val Arg Leu Pro Arg Gln Asp Ala Leu Val Leu Glu 
            20                  25                  30          


Gly Val Arg Ile Gly Ser Glu Ala Asp Pro Ala Pro Leu Leu Gly Gly 
        35                  40                  45              


Arg Leu Leu Leu Met Asp Ile Val Asp Ala Glu Gln Glu Ala Pro Val 
    50                  55                  60                  


Glu Gly Trp Ile Ala Val Ala Tyr Val Gly Lys Glu Gln Ala Ala Gln 
65                  70                  75                  80  


Phe His Gln Glu Asn Lys Gly Ser Gly Pro Gln Ala Tyr Pro Lys Ala 
                85                  90                  95      


Leu Val Gln Gln Met Arg Arg Ala Leu Phe Leu Gly Ala Ser Ala Leu 
            100                 105                 110         


Leu Leu Leu Ile Leu Asn His Asn Val Val Arg Glu Leu Asp Ile Ser 
        115                 120                 125             


Gln Leu Leu Leu Arg Pro Val Ile Val Leu His Tyr Ser Ser Asn Val 
    130                 135                 140                 


Thr Lys Leu Leu Asp Ala Leu Leu Gln Arg Thr Gln Ala Thr Ala Glu 
145                 150                 155                 160 


Ile Thr Ser Gly Glu Ser Leu Ser Ala Asn Ile Glu Trp Lys Leu Thr 
                165                 170                 175     


Leu Trp Thr Thr Cys Gly Leu Ser Lys Asp Gly Tyr Gly Gly Trp Gln 
            180                 185                 190         


Asp Leu Val Cys Leu Gly Gly Ser Arg Ala Gln Glu Gln Lys Pro 
        195                 200                 205         


<210>  3091
<211>  392
<212>  PRT
<213>  Homo Sapiens

<400>  3091

Phe Arg Ser Asp Ser Ser Ser Ser Leu Pro Pro Lys Leu Leu Leu Val 
1               5                   10                  15      


Ser Phe Asp Gly Phe Arg Ala Asp Tyr Leu Lys Asn Tyr Glu Phe Pro 
            20                  25                  30          


His Leu Gln Asn Phe Ile Lys Glu Gly Val Leu Val Glu His Val Lys 
        35                  40                  45              


Asn Val Phe Ile Thr Lys Thr Phe Pro Asn His Tyr Ser Ile Val Thr 
    50                  55                  60                  


Gly Leu Tyr Glu Glu Ser His Gly Ile Val Ala Asn Ser Met Tyr Asp 
65                  70                  75                  80  


Ala Val Thr Lys Lys His Phe Ser Asp Ser Asn Asp Lys Asp Pro Phe 
                85                  90                  95      


Trp Trp Asn Glu Ala Val Pro Ile Trp Val Thr Asn Gln Leu Gln Glu 
            100                 105                 110         


Asn Arg Ser Ser Ala Ala Ala Met Trp Pro Gly Thr Asp Val Pro Ile 
        115                 120                 125             


His Asp Thr Ile Ser Ser Tyr Phe Met Asn Tyr Asn Ser Ser Val Ser 
    130                 135                 140                 


Phe Glu Glu Arg Leu Asn Asn Ile Thr Met Trp Leu Asn Asn Ser Asn 
145                 150                 155                 160 


Pro Pro Val Thr Phe Ala Thr Leu Tyr Trp Glu Glu Pro Asp Ala Ser 
                165                 170                 175     


Gly His Lys Tyr Gly Pro Glu Asp Lys Glu Asn Met Ser Arg Val Leu 
            180                 185                 190         


Lys Lys Ile Asp Asp Leu Ile Gly Asp Leu Val Gln Arg Leu Lys Met 
        195                 200                 205             


Leu Gly Leu Trp Glu Asn Leu Asn Val Ile Ile Thr Ser Asp His Gly 
    210                 215                 220                 


Met Thr Gln Cys Ser Gln Asp Arg Leu Ile Asn Leu Asp Ser Cys Ile 
225                 230                 235                 240 


Asp His Ser Tyr Tyr Thr Leu Ile Asp Leu Ser Pro Val Ala Ala Ile 
                245                 250                 255     


Leu Pro Lys Ile Asn Arg Thr Glu Val Tyr Asn Lys Leu Lys Asn Cys 
            260                 265                 270         


Ser Pro His Met Asn Val Tyr Leu Lys Glu Asp Ile Pro Asn Arg Phe 
        275                 280                 285             


Tyr Tyr Gln His Asn Asp Arg Ile Gln Pro Ile Ile Leu Val Ala Asp 
    290                 295                 300                 


Glu Gly Trp Thr Ile Val Leu Asn Glu Ser Ser Gln Lys Leu Gly Asp 
305                 310                 315                 320 


His Gly Tyr Asp Asn Ser Leu Pro Ser Met His Pro Phe Leu Ala Ala 
                325                 330                 335     


His Gly Pro Ala Phe His Lys Gly Tyr Lys His Ser Thr Ile Asn Ile 
            340                 345                 350         


Val Asp Ile Tyr Pro Met Met Cys His Ile Leu Gly Leu Lys Pro His 
        355                 360                 365             


Pro Asn Asn Gly Thr Phe Gly His Thr Lys Cys Leu Leu Val Asp Gln 
    370                 375                 380                 


Trp Cys Ile Asn Leu Pro Glu Ala 
385                 390         


<210>  3092
<211>  142
<212>  PRT
<213>  Homo Sapiens

<400>  3092

Gln Lys Gln Tyr Trp Val Cys Asn Ser Ser Asp Ala Ser Ile Ser Tyr 
1               5                   10                  15      


Thr Tyr Cys Asp Lys Met Gln Tyr Pro Ile Ser Ile Asn Val Asn Pro 
            20                  25                  30          


Cys Ile Glu Leu Lys Gly Ser Lys Gly Leu Leu His Ile Phe Tyr Ile 
        35                  40                  45              


Pro Arg Arg Asp Leu Lys Gln Leu Tyr Phe Asn Leu Tyr Ile Thr Val 
    50                  55                  60                  


Asn Thr Met Asn Leu Pro Lys Arg Lys Glu Val Ile Cys Arg Gly Ser 
65                  70                  75                  80  


Asp Asp Asp Tyr Ser Phe Cys Arg Ala Leu Lys Gly Glu Thr Val Asn 
                85                  90                  95      


Thr Thr Ile Ser Phe Ser Phe Lys Gly Ile Lys Phe Ser Lys Gly Lys 
            100                 105                 110         


Tyr Lys Cys Val Val Glu Ala Ile Ser Gly Ser Pro Glu Glu Met Leu 
        115                 120                 125             


Phe Cys Leu Glu Phe Val Ile Leu His Gln Pro Asn Ser Asn 
    130                 135                 140         


<210>  3093
<211>  1422
<212>  DNA
<213>  Homo Sapiens

<400>  3093
gccatatttt atgagacgca gcccagcctg tgggcagagt ccgaatcact gctgaaaccc       60

ttggccaatg tgacgctgac gtgccaggcc cgcctggaga ctccagactt ccagctgttc      120

aagaatgggg tggcccagga gcctgtgcac cttgactcac ctgccatcaa gcaccagttc      180

ctgctgacgg gtgacaccca gggccgctac cgctgccgct cgggcttgtc cacaggatgg      240

acccagctga gcaagctcct ggagctgaca gggccaaagt ccttgcctgc tccctggctc      300

tcgatggcgc cagtgtcctg gatcaccccc ggcctgaaaa caacagcagt gtgccgaggt      360

gtgctgcggg gtgtgacttt tctgctgagg cgggagggcg accatgagtt tctggaggtg      420

cctgaggccc aggaggatgt ggaggccacc tttccagtcc atcagcctgg caactacagc      480

tgcagctacc ggaccgatgg ggaaggcgcc ctctctgagc ccagcgctac tgtgaccatt      540

gaggagctcg ctgcaccacc accgcctgtg ctgatgcacc atggagagtc ctcccaggtc      600

ctgcaccctg gcaacaaggt gaccctcacc tgcgtggctc ccctgagtgg agtggacttc      660

cagctacggc gcggggagaa agagctgctg gtacccagga gcagcaccag cccagatcgc      720

atcttctttc acctgaacgc ggtggccctg ggggatggag gtcactacac ctgccgctac      780

cggctgcatg acaaccaaaa cggctggtcc ggggacagcg cgccggtcga gctgattctg      840

agcgatgaga cgctgcccgc gccggagttc tccccggagc cggagtccgg cagggccttg      900

cggctgcggt gcctggcgcc cctggagggc gcgcgcttcg ccctggtgcg cgaggacagg      960

ggcgggcgcc gcgtgcaccg tttccagagc cccgctggga ccgaggcgct cttcgagctg     1020

cacaacattt ccgtggctga ctccgccaac tacagctgcg tctacgtgga cctgaagccg     1080

cctttcgggg gctccgcgcc cagcgagcgc ttggagctgc acgtggacgg accccctccc     1140

aggcctcagc tccgggcgac gtggagtggg gcggtcctgg cgggccgaga tgccgtcctg     1200

cgctgcgagg gacccatccc cgacgtcacc ttcgagctgc tgcgcgaggg cgagacgaag     1260

gccgtgaaga cggtccgcac ccccggggcc gcggcgaacc tcgagctgat cttcgtgggg     1320

ccccagcacg ccggcaacta caggtgccgc taccgctcct gggtgcccca caccttcgaa     1380

tcggagctca gcgaccctgt ggagctcctg gtggcagaaa gc                        1422


<210>  3094
<211>  4353
<212>  DNA
<213>  Homo Sapiens

<400>  3094
tcagtctctg gaaaaccgca gtatatggtt ctggtcccct ccctgctcca cactgagacc       60

actgagaagg gctgtgtcct tctgagctac ctgaatgaga cagtgactgt aagtgcttcc      120

ttggagtctg tcaggggaaa caggagcctc ttcactgacc tggaggcgga gaatgacgta      180

ctccactgtg tcgccttcgc tgtcccaaag tcttcatcca atgaggaggt aatgttcctc      240

actgtccaag tgaaaggacc aacccaagaa tttaagaagc ggaccacagt gatggttaag      300

aacgaggaca gtctggtctt tgtccagaca gacaaatcaa tctacaaacc agggcagaca      360

gtgaaatttc gtgttgtctc catggatgaa aactttcacc ccctgaatga gttgattcca      420

ctagtataca ttcaggatcc caaaggaaat cgcatcgcac aatggcagag tttccagtta      480

gagggtggcc tcaagcaatt ttcttttccc ctctcatcag agcccttcca gggctcctac      540

aaggtggtgg tacagaagaa atcaggtgga aggacagagc accctttcac cgtggaggaa      600

tttgttcttc ccaagtttga agtacaagta acagtgccaa agataatcac catcttggaa      660

gaagagatga atgtatcagt gtgtggccta tacacatatg ggaagcctgt ccctggacat      720

gtgactgtga gcatttgcag aaagtatagt gacgcttccg actgccacgg tgaagattca      780

caggctttct gtgagaaatt cagtggacag ctaaacagcc atggctgctt ctatcagcaa      840

gtaaaaacca aggtcttcca gctgaagagg aaggagtatg aaatgaaact tcacactgag      900

gcccagatcc aagaagaagg aacagtggtg gaattgactg gaaggcagtc cagtgaaatc      960

acaagaacca taaccaaact ctcatttgtg aaagtggact cacactttcg acagggaatt     1020

cccttctttg ggcaggtgcg cctagtagat gggaaaggcg tccctatacc aaataaagtc     1080

atattcatca gaggaaatga agcaaactat tactccaatg ctaccacgga tgagcatggc     1140

cttgtacagt tctctatcaa caccaccaat gttatgggta cctctcttac tgttagggtc     1200

aattacaagg atcgtagtcc ctgttacggc taccagtggg tgtcagaaga acacgaagag     1260

gcacatcaca ctgcttatct tgtgttctcc ccaagcaaga gctttgtcca ccttgagccc     1320

atgtctcatg aactaccctg tggccatact cagacagtcc aggcacatta tattctgaat     1380

ggaggcaccc tgctggggct gaagaagctc tccttctatt atctgataat ggcaaaggga     1440

ggcattgtcc gaactgggac tcatggactg cttgtgaagc aggaagacat gaagggccat     1500

ttttccatct caatccctgt gaagtcagac attgctcctg tcgctcggtt gctcatctat     1560

gctgttttac ctaccgggga cgtgattggg gattctgcaa aatatgatgt tgaaaattgt     1620

ctggccaaca aggtggattt gagcttcagc ccatcacaaa gtctcccagc ctcacacgcc     1680

cacctgcgag tcacagcggc tcctcagtcc gtctgcgccc tccgtgctgt ggaccaaagc     1740

gtgctgctca tgaagcctga tgctgagctc tcggcgtcct cggtttacaa cctgctacca     1800

gaaaaggacc tcactggctt ccctgggcct ttgaatgacc aggacgatga agactgcatc     1860

aatcgtcata atgtctatat taatggaatc acatatactc cagtatcaag tacaaatgaa     1920

aaggatatgt acagcttcct agaggacatg ggcttaaagg cattcaccaa ctcaaagatt     1980

cgtaaaccca aaatgtgtcc acagcttcaa cagtatgaaa tgcatggacc tgaaggtcta     2040

cgtgtaggtt tttatgagtc agatgtaatg ggaagaggcc atgcacgcct ggtgcatgtt     2100

gaagagcctc acacggagac cgtacgaaag tacttccctg agacatggat ctgggatttg     2160

gtggtggtaa actcagcagg tgtggctgag gtaggagtaa cagtccctga caccatcacc     2220

gagtggaagg caggggcctt ctgcctgtct gaagatgctg gacttggtat ctcttccact     2280

gcctctctcc gagccttcca gcccttcttt gtggagctca caatgcctta ctctgtgatt     2340

cgtggagagg ccttcacact caaggccacg gtcctaaact accttcccaa atgcatccgg     2400

gtcagtgtgc agctggaagc ctctcccgcc ttcctagctg tcccagtgga gaaggaacaa     2460

gcgcctcact gcatctgtgc aaacgggcgg caaactgtgt cctgggcagt aaccccaaag     2520

tcattaggaa atgtgaattt cactgtgagc gcagaggcac tagagtctca agagctgtgt     2580

gggactgagg tgccttcagt tcctgaacac ggaaggaaag acacagtcat caagcctctg     2640

ttggttgaac ctgaaggact agagaaggaa acaacattca actccctact ttgtccatca     2700

ggtggtgagg tttctgaaga attatccctg aaactgccac caaatgtggt agaagaatct     2760

gcccgagctt ctgtctcagt tttgggagac atattaggct ctgccatgca aaacacacaa     2820

aatcttctcc agatgcccta tggctgtgga gagcagaata tggtcctctt tgctcctaac     2880

atctatgtac tggattatct aaatgaaaca cagcagctta ctccagaggt caagtccaag     2940

gccattggct atctcaacac tggttaccag agacagttga actacaaaca ctatgatggc     3000

tcctacagca cctttgggga gcgatatggc aggaaccagg gcaacacctg gctcacagcc     3060

tttgttctga agacttttgc ccaagctcga gcctacatct tcatcgatga agcacacatt     3120

acccaagccc tcatatggct ctcccagagg cagaaggaca atggctgttt caggagctct     3180

gggtcactgc tcaacaatgc cataaaggga ggagtagaag atgaagtgac cctctccgcc     3240

tatatcacca tcgcccttct ggagattcct ctcacagtca ctcaccctgt tgtccgcaat     3300

gccctgtttt gcctggagtc agcctggaag acagcacaag aaggggacca tggcagccat     3360

gtatatacca aagcactgct ggcctatgct tttgccctgg caggtaacca ggacaagagg     3420

aaggaagtac tcaagtcact taatgaggaa gctgtgaaga aagacaactc tgtccattgg     3480

gagcgccctc agaaacccaa ggcaccagtg gggcattttt acgaacccca ggctccctct     3540

gctgaggtgg agatgacatc ctatgtgctc ctcgcttatc tcacggccca gccagcccca     3600

acctcggagg acctgacctc tgcaaccaac atcgtgaagt ggatcacgaa gcagcagaat     3660

gcccagggcg gtttctcctc cacccaggac acagtggtgg ctctccatgc tctgtccaaa     3720

tatggagcag ccacatttac caggactggg aaggctgcac aggtgactat ccagtcttca     3780

gggacatttt ccagcaaatt ccaagtggac aacaacaacc gcctgttact gcagcaggtc     3840

tcattgccag agctgcctgg ggaatacagc atgaaagtga caggagaagg atgtgtctac     3900

ctccagacat ccttgaaata caatattctc ccagaaaagg aagagttccc ctttgcttta     3960

ggagtgcaga ctctgcctca aacttgtgat gaacccaaag cccacaccag cttccaaatc     4020

tccctaagtg tcagttacac agggagccgc tctgcctcca acatggcgat cgttgatgtg     4080

aagatggtct ctggcttcat tcccctgaag ccaacagtga aaatgcttga aagatctaac     4140

catgtgagcc ggacagaagt cagcagcaac catgtcttga tttaccttga taaggtgtca     4200

aatcagacac tgagcttgtt cttcacggtt ctgcaagatg tcccagtaag agatctgaaa     4260

ccagccatag tgaaagtcta tgattactac gagacggatg agtttgcaat tgctgagtac     4320

aatgctcctt gcagcaaaga tcttggaaat gct                                  4353


<210>  3095
<211>  3141
<212>  DNA
<213>  Homo Sapiens

<400>  3095
cagaaattgc caaaaggtaa aaggccaaac ctcaaagtcc acatcaatac cacaagtgac       60

tccatcctct tgaagttctt gcgtccaagt ccaaatgtaa agcttgaagg tcttctcctg      120

ggatatggca gcaatgtatc accaaaccag tacttccctc ttcccgctga agggaaattc      180

acagaagcta tagttgatgc agagccgaaa tatctgatag ttgtgcgacc tgctccacct      240

ccaagtcaaa agaagtcatg ttcaggtaaa actcgttctc gcaaacctct gcagctggtg      300

gttggcactc tgacaccgag ctcagtcttc ctgtcctggg gtttcctcat caacccacac      360

catgactgga cattgccaag tcactgtccc aatgacagat tttatacaat tcgctatcga      420

gaaaaggata aagaaaagaa gtggattttt caaatctgtc cagccactga aacaattgtg      480

gaaaacctaa agcccaacac agtttatgaa tttggagtga aagacaatgt ggaaggtgga      540

atttggagta agattttcaa tcacaagact gttgttggaa gtaaaaaagt aaatgggaaa      600

atccaaagta cctatgacca agaccacaca gtgccagcat atgtcccaag gaaactaatc      660

ccaataacaa tcatcaagca agtgattcag aatgttactc acaaggattc agctaaatcc      720

ccagaaaaag ctccactggg aggagtgata ctagtccacc ttattattcc aggtcttaat      780

gaaactactg taaaacttcc tgcatcccta atgtttgaga tttcagatgc actcaagaca      840

caattagcta agaatgaaac cttggcatta cctgccgaat ctaaaacacc agaggttgaa      900

aaaatctcag cacgacccac aacagtgact cctgaaacag ttccaagaag cactaaaccc      960

actacgtcta gtgcattaga tgtttcagaa acaacactgg cttcaagtga aaagccatgg     1020

attgtgccta cagctaaaat atctgaagat tccaaagttc tgcagcctca aactgcaact     1080

tatgatgttt tctcaagccc tacaacatca gatgagcctg agatatcaga ttcctacaca     1140

gcaacaagtg atcgtattct ggattctatc ccacctaaaa cttctagaac tcttgaacag     1200

ccaagggcaa cactggctcc aagtgaaaca ccatttgttc ctcaaaaact ggaaatcttt     1260

accagtccag aaatgcagcc tacgacacct gctccccagc aaactacatc tatcccttct     1320

acacctaaac gacgcccccg gcccaaaccg ccaagaacca aacctgaaag aaccacaagt     1380

gccggaacaa ttacacctaa aatttctaaa agccctgaac ctacatggac aacaccggct     1440

cccggtaaaa cacaatttat ttctctgaaa cctaaaatcc ctctcagccc agaagtgaca     1500

cacaccaaac ctgctcccaa gcagacacca cgtgctcctc ctaagccaaa aacatcacca     1560

cgcccaagaa tcccacaaac acaaccagtt cctaaggtgc cccagcgtgt tactgcaaaa     1620

ccaaaaacgt caccaagtcc agaagtgtca tacaccacac ctgctccaaa agatgtgctc     1680

cttcctcata aaccataccc tgaggtctct cagagcgaac ctgctcctct agagacacga     1740

ggcatccctt ttatacccat gatttcccca agtcctagtc aagaggaact acagaccact     1800

ctggaagaaa cagaccaatc cacccaagaa cctttcacaa ctaagattcc acgaacaact     1860

gaactagcaa agacaactca ggcgccacac agattttata ctactgtgag gcccagaaca     1920

tctgacaagc cacacatcag acctggggtc aagcaagcac ccaggccatc aggtgctgat     1980

agaaatgtat cagtggactc tacccacccc actaaaaagc cagggactcg ccgcccaccc     2040

ttgccaccca gacctacaca cccacgaaga aaacctttac caccaaataa tgtcactgga     2100

aagccaggaa gtgcaggaat catttcatca ggcccaataa ctacaccacc cctgaggtca     2160

acacccaggc ctactggaac tcccttggag agaatagaga cagatataaa gcaaccaaca     2220

gttcctgcct ctggagaaga actggaaaat ataactgact ttagctcaag cccaacaaga     2280

gaaactgatc ctcttgggaa gccaagattc aaaggacctc atgtgcgata catccaaaag     2340

cctgacaaca gtccctgctc cattactgac tctgtcaaac ggttccccaa agaggaggcc     2400

acagagggga atgccaccag cccaccacag aacccaccca ccaacctcac tgtggtcacc     2460

gtggaagggt gcccctcatt tgtcatcttg gactgggaaa agccactaaa tgacactgtc     2520

actgaatatg aagttatatc cagagaaaat gggtcattca gtgggaagaa caagtccatt     2580

caaatgacaa atcagacatt ttccacagta gaaaatctga aaccaaacac gagttatgaa     2640

ttccaggtga aacccaaaaa cccgcttggt gaaggcccgg tcagcaacac agtggcattc     2700

agtactgaat cagcggaccc aagagtgagt gagccagttt ctgcaggaag agatgccatc     2760

tggactgaaa gaccctttaa ttcagactct tactcagagt gtaagggcaa acaatatgtc     2820

aaaaggacat ggtataaaaa atttgtagga gtgcagctgt gcaactctct cagatacaag     2880

atttacttga gcgactccct cacaggaaaa ttttataaca taggtgatca gaggggccat     2940

ggagaagatc actgccagtt tgtggattca tttttagatg gacgcactgg gcagcaactc     3000

acttctgacc agttaccaat caaagaaggt tatttcagag cagttcgcca ggaacctgtc     3060

caatttggag aaataggtgg tcacacccaa atcaattatg ttcagtggta tgaatgtggg     3120

actacaattc ctggaaaatg g                                               3141


<210>  3096
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  3096
ccccaaccgt ccccgctgag ggtcctcctg gggacctccc tcaccatccc ctgctatttc       60

atcgacccca tgcaccctgt gaccaccgcc ccttctaccg ccccactggc cccaagaatc      120

aagtggagcc gtgtgtccaa ggagaaggag gtagtgctgc tggtggccac tgaagggcgc      180

gtgcgggtca acagtgccta tcaggacaag gtctcactgc ccaactaccc ggccatcccc      240

agtgacgcca ccttggaagt ccagagcctg cgctccaatg actctggggt ctaccgctgc      300

gaggtgatgc atggcatcga ggacagcgag gccaccctgg aa                         342


<210>  3097
<211>  2169
<212>  DNA
<213>  Homo Sapiens

<400>  3097
cagtccacca ttgaggaaca ggccaagaca tttttggaca agtttaacca cgaagccgaa       60

gacctgttct atcaaagttc acttgcttct tggaattata acaccaatat tactgaagag      120

aatgtccaaa acatgaataa tgctggggac aaatggtctg cctttttaaa ggaacagtcc      180

acacttgccc aaatgtatcc actacaagaa attcagaatc tcacagtcaa gcttcagctg      240

caggctcttc agcaaaatgg gtcttcagtg ctctcagaag acaagagcaa acggttgaac      300

acaattctaa atacaatgag caccatctac agtactggaa aagtttgtaa cccagataat      360

ccacaagaat gcttattact tgaaccaggt ttgaatgaaa taatggcaaa cagtttagac      420

tacaatgaga ggctctgggc ttgggaaagc tggagatctg aggtcggcaa gcagctgagg      480

ccattatatg aagagtatgt ggtcttgaaa aatgagatgg caagagcaaa tcattatgag      540

gactatgggg attattggag aggagactat gaagtaaatg gggtagatgg ctatgactac      600

agccgcggcc agttgattga agatgtggaa catacctttg aagagattaa accattatat      660

gaacatcttc atgcctatgt gagggcaaag ttgatgaatg cctatccttc ctatatcagt      720

ccaattggat gcctccctgc tcatttgctt ggtgatatgt ggggtagatt ttggacaaat      780

ctgtactctt tgacagttcc ctttggacag aaaccaaaca tagatgttac tgatgcaatg      840

gtggaccagg cctgggatgc acagagaata ttcaaggagg ccgagaagtt ctttgtatct      900

gttggtcttc ctaatatgac tcaaggattc tgggaaaatt ccatgctaac ggacccagga      960

aatgttcaga aagcagtctg ccatcccaca gcttgggacc tggggaaggg cgacttcagg     1020

atccttatgt gcacaaaggt gacaatggac gacttcctga cagctcatca tgagatgggg     1080

catatccagt atgatatggc atatgctgca caaccttttc tgctaagaaa tggagctaat     1140

gaaggattcc atgaagctgt tggggaaatc atgtcacttt ctgcagccac acctaagcat     1200

ttaaaatcca ttggtcttct gtcacccgat tttcaagaag acaatgaaac agaaataaac     1260

ttcctgctca aacaagcact cacgattgtt gggactctgc catttactta catgttagag     1320

aagtggaggt ggatggtctt taaaggggaa attcccaaag accagtggat gaaaaagtgg     1380

tgggagatga agcgagagat agttggggtg gtggaacctg tgccccatga tgaaacatac     1440

tgtgaccccg catctctgtt ccatgtttct aatgattact cattcattcg atattacaca     1500

aggacccttt accaattcca gtttcaagaa gcactttgtc aagcagctaa acatgaaggc     1560

cctctgcaca aatgtgacat ctcaaactct acagaagctg gacagaaact gttcaatatg     1620

ctgaggcttg gaaaatcaga accctggacc ctagcattgg aaaatgttgt aggagcaaag     1680

aacatgaatg taaggccact gctcaactac tttgagccct tatttacctg gctgaaagac     1740

cagaacaaga attcttttgt gggatggagt accgactgga gtccatatgc agaccaaagc     1800

atcaaagtga ggataagcct aaaatcagct cttggagata aagcatatga atggaacgac     1860

aatgaaatgt acctgttccg atcatctgtt gcatatgcta tgaggcagta ctttttaaaa     1920

gtaaaaaatc agatgattct ttttggggag gaggatgtgc gagtggctaa tttgaaacca     1980

agaatctcct ttaatttctt tgtcactgca cctaaaaatg tgtctgatat cattcctaga     2040

actgaagttg aaaaggccat caggatgtcc cggagccgta tcaatgatgc tttccgtctg     2100

aatgacaaca gcctagagtt tctggggata cagccaacac ttggacctcc taaccagccc     2160

cctgtttcc                                                             2169


<210>  3098
<211>  1527
<212>  DNA
<213>  Homo Sapiens

<400>  3098
caggtccgcc ggggccaccc tacagtgcac agtgaaacca agtatgtgga gctaattgtg       60

atcaacgacc accagctgtt cgagcagatg cgacagtcgg tggtcctcac cagcaacttt      120

gccaagtccg tggtgaacct ggccgatgtg atatacaagg agcagctcaa cactcgcatc      180

gtcctggttg ccatggaaac atgggcagat ggggacaaga tccaggtgca ggatgacctc      240

ctggagaccc tggcccggct catggtctac cgacgggagg gtctgcctga gcccagtgat      300

gccacccacc tcttctcggg caggaccttc cagagcacga gcagcggggc agcctacgtg      360

gggggcatat gctccctgtc ccacggcggg ggtgtgaacg agtacggcaa catgggggcg      420

atggccgtga cccttgccca gacgctggga cagaacctgg gcatgatgtg gaacaaacac      480

cggagctcgg caggggactg caagtgtcca gacatctggc tgggctgcat catggaggac      540

actgggttct acctgccccg caagttctcg cgctgtagca tcgacgagta caaccagttt      600

ctgcaggagg gtggtggcag ctgcctcttc aacaagcccc tcaagctcct ggacccccca      660

gagtgcggga acggcttcgt ggaggcaggg gaggagtgcg actgcggctc ggtgcaggag      720

tgcagccgcg caggtggcaa ctgctgcaag aaatgcaccc tgactcacga cgccatgtgc      780

agcgacgggc tctgctgtcg ccgctgcaag tacgaaccac ggggtgtgtc ctgccgagag      840

gccgtgaacg agtgcgacat cgcggagacc tgcaccgggg actctagcca gtgcccgcct      900

aacctgcaca agctggacgg ttactactgt gaccatgagc agggccgctg ctacggaggt      960

cgctgcaaaa cccgggaccg gcagtgccag gttctttggg gccatgcggc tgctgatcgc     1020

ttctgctacg agaagctgaa tgtggagggg acggagcgtg ggagctgtgg gcgcaaggga     1080

tctggctggg tccagtgcag taagcaggac gtgctgtgtg gcttcctcct ctgtgtcaac     1140

atctctggag ctcctcggct aggggacctg gtgggagaca tcagtagtgt caccttctac     1200

caccagggca aggagctgga ctgcagggga ggccacgtgc agctggcgga cggctctgac     1260

ctgagctatg tggaggatgg cacagcctgc gggcctaaca tgttgtgcct ggaccatcgc     1320

tgcctgccag cttctgcctt caacttcagc acctgccccg gcagtgggga gcgccggatt     1380

tgctcccacc acggggtctg cagcaatgaa gggaagtgca tctgtcagcc agactggaca     1440

ggcaaagact gcagtatcca taaccccctg cccacgtccc cacccacggg ggagacggag     1500

agatataaag gtcccagcgg caccaac                                         1527


<210>  3099
<211>  1599
<212>  DNA
<213>  Homo Sapiens

<400>  3099
gagaccctca aggcaactaa gtatgtggag ctggtgatcg tggcagacaa ccgagagttt       60

cagaggcaag gaaaagatct ggaaaaagtt aagcagcgat taatagagat tgctaatcac      120

gttgacaagt tttacagacc actgaacatt cggatcgtgt tggtaggcgt ggaagtgtgg      180

aatgacatgg acaaatgctc tgtaagtcag gacccattca ccagcctcca tgaatttctg      240

gactggagga agatgaagct tctacctcgc aaatcccatg acaatgcgca gcttgtcagt      300

ggggtttatt tccaagggac caccatcggc atggccccaa tcatgagcat gtgcacggca      360

gaccagtctg ggggaattgt catggaccat tcagacaatc cccttggtgc agccgtgacc      420

ctggcacatg agctgggcca caatttcggg atgaatcatg acacactgga caggggctgt      480

agctgtcaaa tggcggttga gaaaggaggc tgcatcatga acgcttccac cgggtaccca      540

tttcccatgg tgttcagcag ttgcagcagg aaggacttgg agaccagcct ggagaaagga      600

atgggggtgt gcctgtttaa cctgccggaa gtcagggagt ctttcggggg ccagaagtgt      660

gggaacagat ttgtggaaga aggagaggag tgtgactgtg gggagccaga ggaatgtatg      720

aatcgctgct gcaatgccac cacctgtacc ctgaagccgg acgctgtgtg cgcacatggg      780

ctgtgctgtg aagactgcca gctgaagcct gcaggaacag cgtgcaggga ctccagcaac      840

tcctgtgacc tcccagagtt ctgcacaggg gccagccctc actgcccagc caacgtgtac      900

ctgcacgatg ggcactcatg tcaggatgtg gacggctact gctacaatgg catctgccag      960

actcacgagc agcagtgtgt cacgctctgg ggaccaggtg ctaaacctgc ccctgggatc     1020

tgctttgaga gagtcaattc tgcaggtgat ccttatggca actgtggcaa agtctcgaag     1080

agttcctttg ccaaatgcga gatgagagat gctaaatgtg gaaaaatcca gtgtcaagga     1140

ggtgccagcc ggccagtcat tggtaccaat gccgtttcca tagaaacaaa catccccctg     1200

cagcaaggag gccggattct gtgccggggg acccacgtgt acttgggcga tgacatgccg     1260

gacccagggc ttgtgcttgc aggcacaaag tgtgcagatg gaaaaatctg cctgaatcgt     1320

caatgtcaaa atattagtgt ctttggggtt cacgagtgtg caatgcagtg ccacggcaga     1380

ggggtgtgca acaacaggaa gaactgccac tgcgaggccc actgggcacc tcccttctgt     1440

gacaagtttg gctttggagg aagcacagac agcggcccca tccggcaagc agggaaagaa     1500

gcaaggcagg aagctgcaga gtccaacagg gagcgcggcc agggccagga gcccgtggga     1560

tcgcaggagc atgcgtctac tgcctcactg acactcatc                            1599


<210>  3100
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  3100
gatgtggtaa cagagaccaa gactgtggag ttggtgattg tggctgatca ctcggaggcc       60

cagaaatacc gggacttcca gcacctgcta aaccgcacac tggaagtggc cctcttgctg      120

gacacattct tccggcccct gaatgtacga gtggcactag tgggcctgga ggcctggacc      180

cagcgtgacc tggtggagat cagcccaaac ccagctgtca ccctcgaaaa cttcctccac      240

tggcgcaggg cacatttgct gcctcgattg ccccatgaca gtgcccagct ggtgactggt      300

acttcattct ctgggcctac ggtgggcatg gccattcaga actccatctg ttctcctgac      360

ttctcaggag gtgtgaacat ggaccactcc accagcatcc tgggagtcgc ctcctccata      420

gcccatgagt tgggccacag cctgggcctg gaccatgatt tgcctgggaa tagctgcccc      480

tgtccaggtc cagccccagc caagacctgc atcatggagg cctccacaga cttcctacca      540

ggcctgaact tcagcaactg cagccgacgg gccctggaga aagccctcct ggatggaatg      600

ggcagctgcc tcttcgaacg gctgcctagc ctacccccta tggctgcttt ctgcggaaat      660

atgtttgtgg agccgggcga gcagtgtgac tgtggcttcc tggatgactg cgtcgatccc      720

tgctgtgatt ctttgacctg ccagctgagg ccaggtgcac agtgtgcatc tgacggaccc      780

tgttgtcaaa attgccagct gcgcccgtct ggctggcagt gtcgtcctac cagaggggat      840

tgtgacttgc ctgaattctg cccaggagac agctcccagt gtccccctga tgtcagccta      900

ggggatggcg agccctgcgc tggcgggcaa gctgtgtgca tgcacgggcg ttgtgcctcc      960

tatgcccagc agtgccagtc actttgggga cctggagccc agcccgctgc gccactttgc     1020

ctccagaccg ctaatactcg gggaaatgct tttgggagct gtgggcgcaa ccccagtggc     1080

agttatgtgt cctgcacccc tagagatgcc atttgtgggc agctccagtg ccagacaggt     1140

aggacccagc ctctgctggg ctccatccgg gatctactct gggagacaat agatgtgaat     1200

gggactgagc tgaactgcag ctgggtgcac ctggacctgg gcagtgatgt ggcccagccc     1260

ctcctgactc tgcctggcac agcctgtggc cctggcctgg tgtgtataga ccatcgatgc     1320

cagcgtgtgg atctcctggg ggcacaggaa tgtcgaagca aatgccatgg acatggggtc     1380

tgtgacagca acaggcactg ctactgtgag gagggctggg caccccctga ctgcaccact     1440

cagctcaaag caaccagctc cctgaccaca                                      1470


<210>  3101
<211>  1533
<212>  DNA
<213>  Homo Sapiens

<400>  3101
aatctttcaa aactattacc ccaatatctg gaaatataca ttatagtgga aaaagctttg       60

tatgattata tgggatctga aatgatggct gtaacacaaa aaattgtcca ggttattggg      120

cttgtcaaca ctatgtttac ccagttcaaa ttgactgtta tactgtcttc cttggaattg      180

tggtcaaatg aaaaccagat ttccaccagt ggggatgctg atgatatatt acaaagattt      240

ttggcatgga aacgggacta tctcatccta cggccccatg acatagcata cttacttgtt      300

tacaggaaac atcctaaata tgtgggagca acatttcctg gcactgtatg caataaaagc      360

tatgatgcag gtattgctat gtatccagat gcaataggtt tggagggatt ttcggttatt      420

atagctcaac tgcttggcct taatgtagga ttaacatatg atgacatcac tcagtgtttc      480

tgtctgagag ctacatgcat catgaatcat gaagcagtga gtgccagtgg tagaaagatt      540

tttagcaact gcagcatgca cgactataga tattttgttt caaaatttga gactaaatgc      600

cttcagaagc tttcaaattt gcaaccatta catcaaaatc aaccagtgtg tggtaatggg      660

attttggaat ccaatgaaga atgtgactgt ggtaataaaa atgaatgtca atttaagaag      720

tgctgtgatt ataacacatg taaactgaag ggctcagtaa aatgtggttc tggaccatgt      780

tgtacatcaa agtgtgagtt gtcaatagca ggcactccat gtagaaagag tattgatcca      840

gagtgtgatt ttacagagta ctgcaatgga acctctagta attgtgttcc tgacacttat      900

gcattgaatg gccgtttgtg caagttggga actgcctatt gctataacgg acaatgtcaa      960

actactgata accagtgtgc caagatattt ggaaaaggtg ctcaaggtgc tccatttgcc     1020

tgttttaaag aagttaattc tctgcatgaa agatctgaaa actgtggttt taaaaattca     1080

caaccattac cttgtgaacg gaaggatgtt ctctgtggaa aattagcttg tgttcagcca     1140

cataaaaatg ctaataaaag tgacgctcaa tctacagttt attcatatat tcaagaccat     1200

gtatgtgtat ctatagccac tggttcctcc atgagatcag atggaacaga caatgcctat     1260

gtggctgatg gcaccatgtg tggtccagaa atgtactgtg taaataaaac ctgcagaaaa     1320

gttcatttaa tgggatataa ctgtaatgcc accacaaaat gcaaagggaa agggatatgt     1380

aataattttg gtaattgtca atgcttccct ggacatagac ctccagattg taaattccag     1440

tttggttccc cagggggtag tattgatgat ggaaattttc agaaatctgg tgacttttat     1500

actgaaaaag gctacaatac acactggaac aac                                  1533


<210>  3102
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  3102
agggaagatt taaactccat gaagtatgtg gagctttacc tcgtggctga ttatttagag       60

tttcagaaga atcgacgaga ccaggacgcc accaaacaca agctcataga gatcgccaac      120

tatgttgata agttttaccg atccttgaac atccggattg ctctcgtggg cttggaagtg      180

tggacccacg ggaacatgtg tgaagtttca gagaatccat attctaccct ctggtccttt      240

ctcagttgga ggcgcaagct gcttgcccag aagtaccatg acaacgccca attaatcacg      300

ggcatgtcct tccacggcac caccatcggc ctggcccccc tcatggccat gtgctctgtg      360

taccagtctg gaggagtcaa catggaccac tccgagaatg ccattggcgt ggctgccacc      420

atggcccacg agatgggcca caactttggc atgacccatg attctgcaga ttgctgctcg      480

gccagtgcgg ctgatggtgg gtgcatcatg gcagctgcca ctgggcaccc ctttcccaaa      540

gtgttcaatg gatgcaacag gagggagctg gacaggtatc tgcagtcagg tggtggaatg      600

tgtctctcca acatgccaga caccaggatg ttgtatggag gccggaggtg tgggaacggg      660

tatctggaag atggggaaga gtgtgactgt ggagaagaag aggaatgtaa caacccctgc      720

tgcaatgcct ctaattgtac cctgaggccg ggggcggagt gtgctcacgg ctcctgctgc      780

caccagtgta agctgttggc tcctgggacc ctgtgccgcg agcaggccag gcagtgtgac      840

ctcccggagt tctgtacggg caagtctccc cactgcccta ccaacttcta ccagatggat      900

ggtaccccct gtgagggcgg ccaggcctac tgctacaacg gcatgtgcct cacctaccag      960

gagcagtgcc agcagctgtg gggacccgga gcccgacctg cccctgacct ctgcttcgag     1020

aaggtgaatg tggcaggaga cacctttgga aactgtggaa aggacatgaa tggtgaacac     1080

aggaagtgca acatgagaga tgcgaagtgt gggaagatcc agtgtcagag ctctgaggcc     1140

cggcccctgg agtccaacgc ggtgcccatt gacaccacta tcatcatgaa tgggaggcag     1200

atccagtgcc ggggcaccca cgtctaccga ggtcctgagg aggagggtga catgctggac     1260

ccagggctgg tgatgactgg aaccaagtgt ggctacaacc atatttgctt tgaggggcag     1320

tgcaggaaca cctccttctt tgaaactgaa ggctgtggga agaagtgcaa tggccatggg     1380

gtctgtaaca acaaccagaa ctgccactgc ctgccgggct gggccccgcc cttctgcaac     1440

acaccgggcc acgggggcag tatcgacagt gggcctatgc cccctgagag t              1491


<210>  3103
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  3103
tataatcata tggggtctga tacaactgtt gtcgctcaaa aagttttcca gttgattgga       60

ttgacgaatg ctatttttgt ttcatttaat attacaatta ttctgtcttc attggagctt      120

tggatagatg aaaataaaat tgcaaccact ggagaagcta atgagttatt acacacattt      180

ttaagatgga aaacatctta tcttgtttta cgtcctcatg atgtggcatt tttacttgtt      240

tacagagaaa agtcaaatta tgttggtgca acctttcaag ggaagatgtg tgatgcaaac      300

tatgcaggag gtgttgttct gcaccccaga accataagtc tggaatcact tgcagttatt      360

ttagctcaat tattgagcct tagtatgggg atcacttatg atgacattaa caaatgccag      420

tgctcaggag ctgtctgcat tatgaatcca gaagcaattc atttcagtgg tgtgaagatc      480

tttagtaact gcagcttcga agactttgca cattttattt caaagcagaa gtcccagtgt      540

cttcacaatc agcctcgctt agatcctttt ttcaaacagc aagcagtgtg tggtaatgca      600

aagctggaag caggagagga gtgtgactgt gggactgaac aggattgtgc ccttattgga      660

gaaacatgct gtgatattgc cacatgtaga tttaaagccg gttcaaactg tgctgaagga      720

ccatgctgcg aaaactgtct atttatgtca aaagaaagaa tgtgtaggcc ttcctttgaa      780

gaatgcgacc tccctgaata ttgcaatgga tcatctgcat catgcccaga aaaccactat      840

gttcagactg ggcatccgtg tggactgaat caatggatct gtatagatgg agtttgtatg      900

agtggggata aacaatgtac agacacattt ggcaaagaag tagagtttgg cccttcagaa      960

tgttattctc accttaattc aaagactgat gtatctggaa actgtggtat aagtgattca     1020

ggatacacac agtgtgaagc tgacaatctg cagtgcggaa aattaatatg taaatatgta     1080

ggtaaatttt tattacaaat tccaagagcc actattattt atgccaacat aagtggacat     1140

ctctgcattg ctgtggaatt tgccagtgat catgcagaca gccaaaagat gtggataaaa     1200

gatggaactt cttgtggttc aaataaggtt tgcaggaatc aaagatgtgt gagttcttca     1260

tacttgggtt atgattgtac tactgacaaa tgcaatgata gaggtgtatg caataacaaa     1320

aagcactgtc actgtagtgc ttcatattta cctccagatt gctcagttca atcagatcta     1380

tggcctggtg ggagtattga cagtggcaat tttccacctg tagctatacc agccagactc     1440

cctgaaaggc gctacattga gaacatttac cattccaaac caatgaga                  1488


<210>  3104
<211>  1461
<212>  DNA
<213>  Homo Sapiens

<400>  3104
cggtttgttg agctggtagt ggtcgtggat aatattagat atcttttctc tcaaagtaat       60

gcaacaacag tgcagcatga agtatttaac gttgtcaata tagtggattc cttctatcat      120

cctttggagg ttgatgtaat tttgactgga attgatatat ggactgcatc aaatccactt      180

cctaccagtg gagacctaga taatgtttta gaggactttt ctatttggaa gaattataac      240

cttaataatc gactacaaca tgatgttgca catcttttca taaaagacac acaaggcatg      300

aagcttggtg ttgcctatgt taaaggaata tgccagaatc cttttaatac tggagttgat      360

gtttttgaag acaacaggtt ggtcgttttt gcaattactt tgggccacga gcttggtcat      420

aatttgggta tgcaacatga cacccagtgg tgtgtgtgcg agctacagtg gtgcataatg      480

catgcctata gaaaggtgac aactaaattt agcaactgca gttatgccca atattgggac      540

agtactatca gtagtggatt atgtattcaa ccgcctccat atccagggaa tatatttaga      600

ctgaagtact gtgggaatct agtggttgaa gaaggggagg aatgtgactg tggaaccata      660

cggcagtgtg caaaagatcc ctgttgtctg ttaaactgta ctctacatcc tggggctgct      720

tgtgcttttg gaatatgttg caaagactgc aaatttctgc catcaggaac tttatgtaga      780

caacaagttg gtgaatgtga ccttccagag tggtgcaatg ggacatccca tcaatgccca      840

gatgatgtgt atgtgcagga cgggatctcc tgtaatgtga atgccttctg ctatgaaaag      900

acgtgtaata accatgatat acaatgtaaa gagatttttg gccaagatgc aaggagtgca      960

tctcagagtt gctaccaaga aatcaacacc caaggaaacc gtttcggtca ctgtggtatt     1020

gtaggcacaa catatgtaaa atgttggacc cctgatatca tgtgtgggag ggttcagtgt     1080

gaaaatgtgg gagtaattcc caatctgata gagcattcta cagtgcagca gtttcacctc     1140

aatgacacca cttgctgggg cactgattat catttaggga tggctatacc tgatattggt     1200

gaggtgaaag atggcacagt atgtggtcca gaaaagatct gcatccgtaa gaagtgtgcc     1260

agtatggttc atctgtcaca agcctgtcag cctaagacct gcaacatgag gggaatctgc     1320

aacaacaaac aacactgtca ctgcaaccat gaatgggcac ccccatactg caaggacaaa     1380

ggctatggag gtagtgctga tagtggccca cctcctaaga acaacatgga aggattaaat     1440

gtgatgggaa agttgcgtta c                                               1461


<210>  3105
<211>  1401
<212>  DNA
<213>  Homo Sapiens

<400>  3105
ccaaaatctg ctggtgactg gtggactcat gcatggtttc tggagctagt tgttgtggtg       60

aaccatgatt tcttcattta ctctcaaagc aacatctcaa aggtgcaaga ggatgtattt      120

cttgttgtca acatagtgga ttccatgtat cagcagttag gtacttacat aattttgatt      180

ggaattgaaa tttggaatca aggaaatgtt ttcccaatga caagcataga acaggtcctg      240

aacgatttct ctcaatggaa acaaatcagt ctttcccagc tacagcatga tgctgcacat      300

atgttcataa aaaattcact tataagtata cttggcctag cctatgttgc aggaatatgt      360

cgtccaccta ttgattgtgg agttgataat tttcaaggag atacctggtc tctttttgcc      420

aacactgtgg cccatgagtt aggtcatacg ttgggtatgc agcatgatga agaattctgt      480

ttttgtgggg aaagaggttg catcatgaat acttttagag tgccagcaga gaaattcacc      540

aattgcagtt acgctgattt tatgaagacc accttaaacc agggatcatg tctgcataat      600

cctccaagat tgggggaaat ctttatgcta aagcgctgtg ggaatggtgt ggttgaaaga      660

gaagagcagt gtgactgtgg atccgtacag cagtgtgaac aagacgcctg ttgtctgttg      720

aactgcactc taaggcctgg ggctgcctgt gcttttgggc tttgttgcaa agactgcaag      780

ttcatgccat caggggaact ctgtagacaa gaggtcaatg aatgtgacct tccagaatgg      840

tgcaatggaa catctcatca gtgtccagaa gatagatatg tgcaggacgg gatcccctgt      900

agtgacagtg cctactgcta tcaaaagagg tgtaataacc atgaccagca ttgcagggag      960

atttttggta aagatgcaaa aagtgcatct cagaattgct ataaagaaat caactctcag     1020

ggaaaccgtt ttggtcactg tggtataaat ggcacaacat acctaaaatg tcatatctct     1080

gatgtctttt gtgggagagt tcaatgtgag aatgtgagag acattcctct tctccaagat     1140

cattttactt tgcagcacac tcatatcaat ggtgtcacct gctggggtat tgactatcat     1200

ttaaggatga acatatctga cattggtgaa gtgaaagatg gtactgtgtg tggcccagga     1260

aagatctgca tccataagaa gtgtgtcagt ctgtctgtct tgtcacatgt ctgccttcct     1320

gagacctgca atatgaaggg gatctgcaat aacaaacatc actgccactg tggctatggg     1380

tggtccccac cctactgcca g                                               1401


<210>  3106
<211>  1542
<212>  DNA
<213>  Homo Sapiens

<400>  3106
agtaaacggc agcttcgtcg atatcctcgt aatgtagaag aagaaaccaa atacattgaa       60

ctgatgattg tgaatgatca ccttatgttt aaaaaacatc ggctttccgt tgtacatacc      120

aatacctatg cgaaatctgt ggtgaacatg gcagatttaa tatataaaga ccaacttaag      180

accaggatag tattggttgc tatggaaacc tgggcgactg acaacaagtt tgccatatct      240

gaaaatccat tgatcaccct acgtgagttt atgaaataca ggagggattt tatcaaagag      300

aaaagtgatg cagttcacct tttttcggga agtcaatttg agagtagccg gagcggggca      360

gcttatattg gtgggatttg ctcgttgctg aaaggaggag gcgtgaatga atttgggaaa      420

actgatttaa tggctgttac acttgcccag tcattagccc ataatattgg tattatctca      480

gacaaaagaa agttagcaag tggtgaatgt aaatgcgagg acacgtggtc cgggtgcata      540

atgggagaca ctggctatta tcttcctaaa aagttcaccc agtgtaatat tgaagagtat      600

catgacttcc tgaatagtgg aggtggtgcc tgccttttca acaaaccttc taagcttctt      660

gatcctcctg agtgtggcaa tggcttcatt gaaactggag aggagtgtga ttgtggaacc      720

ccggccgaat gtgtccttga aggagcagag tgttgtaaga aatgcacctt gactcaagac      780

tctcaatgca gtgacggtct ttgctgtaaa aagtgcaagt ttcagcctat gggcactgtg      840

tgccgagaag cagtaaatga ttgtgatatt cgtgaaacgt gctcaggaaa ttcaagccag      900

tgtgccccta atattcataa aatggatgga tattcatgtg atggtgttca gggaatttgc      960

tttggaggaa gatgcaaaac cagagataga caatgcaaat acatttgggg gcaaaaggtg     1020

acagcatcag acaaatattg ctatgagaaa ctgaatattg aagggacgga gaagggtaac     1080

tgtgggaaag acaaagacac atggatacag tgcaacaaac gggatgtgct ttgtggttac     1140

cttttgtgta ccaatattgg caatatccca aggcttggag aactcgatgg tgaaatcaca     1200

tctactttag ttgtgcagca aggaagaaca ttaaactgca gtggtgggca tgttaagctt     1260

gaagaagatg tagatcttgg ctatgtggaa gatgggacac cttgtggtcc ccaaatgatg     1320

tgcttagaac acaggtgtct tcctgtggct tctttcaact ttagtacttg cttgagcagt     1380

aaagaaggca ctatttgctc aggaaatgga gtttgcagta atgagctgaa gtgtgtgtgt     1440

aacagacact ggataggttc tgattgcaac acttacttcc ctcacaatga tgatgcaaag     1500

actggtatca ctctgtctgg caatggtgtt gctggcacca at                        1542


<210>  3107
<211>  1518
<212>  DNA
<213>  Homo Sapiens

<400>  3107
gcagtcaacc catctcgtgg tatattcgag gagatgaagt atttggaatt gatgatcgtt       60

aacgatcata agacctacaa aaagcataga agttcccatg ctcacaccaa caattttgcg      120

aaaagtgtgg tgaatctggt ggacagtatt tacaaggagc agttaaatac tagagtagta      180

ttagttgctg tagagacatg gacagaaaag gatcagatag acatcactac aaatcccgta      240

cagatgttgc atgaatttag taagtacagg cagcgtataa aacagcacgc cgatgctgtg      300

catctaattt ctcgtgtgac tttccactat aagaggtcca gcctgtccta cttcggaggg      360

gtatgttcca gaacgcgtgg agttggtgtt aatgaatatg ggctaccaat ggctgtcgcc      420

caggtgctta gtcagagctt agcccagaat ctggggatcc aatgggagcc atcttcaaga      480

aaaccaaagt gcgactgtac tgagtcatgg ggggggtgca tcatggagga aaccggagtg      540

tcccactccc gtaaattcag taaatgcagt attctagagt atagagactt tctgcaaaga      600

ggcggcggag cgtgtctgtt taacagacct accaaactgt ttgagcccac cgagtgcggt      660

aacgggtatg tagaggcagg tgaagagtgt gactgtggct ttcatgtgga atgctacggt      720

ctatgctgta aaaaatgcag tctatccaac ggtgctcatt gctccgacgg cccctgttgt      780

aacaacacat cttgtttgtt ccagccgcgt ggatatgaat gcagggatgc ggtaaacgag      840

tgcgacatca ctgaatactg tacgggcgac tcaggccaat gtcctcccaa tttgcacaaa      900

caagacggct acgcttgtaa ccagaatcaa gggcgttgtt ataatggtga gtgtaagacc      960

cgtgacaatc aatgtcagta catctggggg acgaaggccg ccggaagcga caagttctgc     1020

tacgaaaagt taaacaccga gggtactgaa aagggtaatt gtggtaagga cggtgacagg     1080

tggattcaat gttccaagca tgacgtgttt tgtgggtttt tgctgtgtac taaccttacg     1140

agagccccga gaattggcca gctacaaggg gaaatcatac ctacaagttt ctatcaccag     1200

ggacgtgtta tcgactgcag tggggcacac gtcgtactag acgatgacac tgatgttggg     1260

tatgtggaag atggtacacc ctgtggccca tccatgatgt gcttagatag gaaatgttta     1320

caaatccaag cgctaaacat gtccagctgt ccccttgaca gcaagggcaa ggtgtgctca     1380

ggacatggag tttgttcaaa tgaggcaact tgtatttgcg acttcacttg ggcaggcaca     1440

gattgttcaa ttcgtgaccc agtcagaaac ctacaccccc cgaaagacga ggggcccaaa     1500

ggtccctctg cgactaat                                                   1518


<210>  3108
<211>  1401
<212>  DNA
<213>  Homo Sapiens

<400>  3108
gttcaggaac atgagaaata catagaatat tatttggtcc tggataatgg tgagtttaaa       60

aggtacaatg agaatcaaga tgagatcaga aagagggtat ttgagatggc taattatgtc      120

aacatgcttt ataaaaagct caatactcat gtggccttag ttggtatgga aatctggact      180

gacaaggata agataaagat aaccccaaat gcaagcttca ccttggagaa tttttctaaa      240

tggaggggga gtgttctctc aagaagaaag cgtcatgata ttgctcagtt aatcacagca      300

acagaacttg ctggaacgac tgtgggtctt gcatttatgt ctacaatgtg ttctccttat      360

tctgttggcg ttgttcagga ccacagcgat aatcttctta gagttgcagg gacaatggca      420

catgaaatgg gccacaactt tggaatgttt catgacgact attcttgcaa gtgtccttct      480

acaatatgtg tgatggacaa agcactgagc ttctatatac ccacagactt cagttcctgc      540

agccgtctca gctatgacaa gttttttgaa gataaattat caaattgcct ctttaatgct      600

ccattgccta cagatatcat atccactcca atttgtggga accagttggt ggaaatggga      660

gaggactgtg attgtgggac atctgaggaa tgtaccaata tttgctgtga tgctaagaca      720

tgtaaaatca aagcaacttt tcaatgtgca ttaggagaat gttgtgaaaa atgccaattt      780

aaaaaggctg ggatggtgtg cagaccagca aaagatgagt gcgacctgcc tgaaatgtgt      840

aatggtaaat ctggtaattg tcctgatgat agattccaag tcaatggctt cccttgccat      900

cacgggaagg gccactgctt gatggggaca tgccccacac tgcaggagca gtgcacagag      960

ctgtggggac caggaactga ggttgcagat aagtcatgtt acaacaggaa tgaaggtggg     1020

tcaaagtacg ggtactgtcg cagagtggat gacacactca ttccctgcaa agcaaatgat     1080

accatgtgtg ggaagttgtt ctgtcaaggt gggtcggata atttgccctg gaaaggacgg     1140

atagtgactt tcctgacatg taaaacattt gatcctgaag acacaagtca agaaataggc     1200

atggtggcca atggaactaa gtgtggcgat aacaaggttt gcattaatgc agaatgtgtg     1260

gatattgaga aagcctacaa atcaaccaat tgctcatcta agtgcaaagg acatgctgtg     1320

tgtgaccatg agctccagtg tcaatgtgag gaaggatgga tccctcccga ctgcgatgac     1380

tcctcagtgg tcttccactt c                                               1401


<210>  3109
<211>  1443
<212>  DNA
<213>  Homo Sapiens

<400>  3109
tggatccatt ttaggattgt tgaaattgta gtcgtcattg ataattatct gtacattcgt       60

tatgaaagga acgactcaaa gttgctggag gatctatatg ttattgttaa tatagtggat      120

tccattttgg atgtcattgg tgttaaggtg ttattatttg gtttggagat ctggaccaat      180

aaaaacctca ttgtagtaga tgatgtaagg aaatctgtgc acctgtattg caagtggaag      240

tcggagaaca ttacgccccg gatgcaacat gacacctcac atcttttcac aactctagga      300

ttaagagggt taagtggcat aggagctttt agaggaatgt gtacaccaca ccgtagttgt      360

gcaattgtta ctttcatgaa caaaactttg ggcacttttt caattgcagt ggctcatcat      420

ctaggtcata atttgggcat gaaccatgat gaggatacat gtcgttgttc acaacctaga      480

tgcataatgc atgaaggcaa cccaccaata actaaattta gcaattgtag ttatggtgat      540

ttttgggaat atactgtaga gaggacaaag tgtttgcttg aaacagtaca cacaaaggac      600

atctttaatg tgaagcgctg tgggaatggt gttgttgaag aaggagaaga gtgtgactgt      660

ggacctttaa agcattgtgc aaaagatccc tgctgtctgt caaattgcac tctgactgat      720

ggttctactt gtgcttttgg gctttgttgc aaagactgca agttcctacc atcagggaaa      780

gtgtgtagaa aggaggtcaa tgaatgtgat cttccagagt ggtgcaatgg tacttcccat      840

aagtgcccag atgactttta tgtggaagat ggaattccct gtaaggagag gggctactgc      900

tatgaaaaga gctgtcatga ccgcaatgaa cagtgtagga ggatttttgg tgcaggcgca      960

aatactgcaa gtgagacttg ctacaaagaa ttgaacacct taggtgaccg tgttggtcac     1020

tgtggtatca aaaatgctac atatataaag tgtaatatct cagatgtcca gtgtggaaga     1080

attcagtgtg agaatgtgac agaaattccc aatatgagtg atcatactac tgtgcattgg     1140

gctcgcttca atgacataat gtgctggagt actgattacc atttggggat gaagggacct     1200

gatattggtg aagtgaaaga tggaacagag tgtgggatag atcatatatg catccacagg     1260

cactgtgtcc atataaccat cttgaatagt aattgctcac ctgcattttg taacaagagg     1320

ggcatctgca acaataaaca tcactgccat tgcaattatc tgtgggaccc tcccaactgc     1380

ctgataaaag gctatggagg tagtgttgac agtggcccac cccctaagag aaagaagaaa     1440

aag                                                                   1443


<210>  3110
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  3110
tataaacacc caaagtactt ggaattgatc ctactctttg atcaaagtag gtataggttt       60

gtgaacaaca atctttctca agtcatacat gatgccattc ttttgactgg gattatggac      120

acctactttc aagatgttcg tatgaggata cacttaaagg ctcttgaagt atggacagat      180

tttaacaaaa tacgcgttgg atatccagag ttagctgaag ttttaggcag atttgtaata      240

tataaaaaaa gtgtattaaa tgctcgcctg tcatcagatt gggcacattt atatcttcaa      300

agaaaatata atgatgctct tgcatggtcg tttggaaaag tgtgttctct agaatatgct      360

ggatcagtga gtactttact agatacaaat atccttgccc ctgctacctg gtctgctcat      420

gagctgggtc atgctgtagg aatgtcacat gatgaacaat actgccaatg taggggtagg      480

cttaattgca tcatgggctc aggacgcact gggtttagca attgcagtta tatctctttt      540

tttaaacata tctcttcggg agcaacatgt ctaaataata tcccaggact aggttatgtg      600

cttaagagat gtggaaacaa aattgtggag gacaatgagg aatgtgactg tggttccaca      660

gaggagtgtc agaaagatcg gtgttgccaa tcaaattgta agttgcaacc aggtgccaac      720

tgtagcattg gactttgctg tcatgattgt cggtttcgtc catctggata cgtgtgtagg      780

caggaaggaa atgaatgtga ccttgcagag tactgcgacg ggaattcaag ttcctgccca      840

aatgacgttt ataagcagga tggaacccct tgcaagtatg aaggccgttg tttcaggaag      900

gggtgcagat ccagatatat gcagtgccaa agcatttttg gacctgatgc catggaggct      960

cctagtgagt gctatgatgc agttaactta ataggtgatc aatttggtaa ctgtgagatt     1020

acaggaattc gaaattttaa aaagtgtgaa agtgcaaatt caatatgtgg caggctacag     1080

tgtataaatg ttgaaaccat ccctgatttg ccagagcata cgactataat ttctactcat     1140

ttacaggcag aaaatctcat gtgctggggc acaggctatc atctatccat gaaacccatg     1200

ggaatacctg acctaggtat gataaatgat ggcacctcct gtggagaagg ccgggtatgt     1260

tttaaaaaaa attgcgtcaa tagctcagtc ctgcagtttg actgtttgcc tgagaaatgc     1320

aatacccggg gtgtttgcaa caacagaaaa aactgccact gcatgtatgg gtgggcacct     1380

ccattctgtg aggaagtggg gtatggagga agcattgaca gtgggcctcc aggactgctc     1440

agaggggcga ttccctcgtc aatttgg                                         1467


<210>  3111
<211>  1524
<212>  DNA
<213>  Homo Sapiens

<400>  3111
aaatcagaac cagctgttcc agatttattt cctctttatc tagaaatgca tattgtggtg       60

gacaaaactt tgtatgatta ctggggctct gatagcatga tagtaacaaa taaagtcatc      120

gaaattgttg gccttgcaaa ttcaatgttc acccaattta aagttactat tgtgctgtca      180

tcattggagt tatggtcaga tgaaaataag atttctacag ttggtgaggc agatgaatta      240

ttgcaaaaat ttttagaatg gaaacaatct tatcttaacc taaggcctca tgatattgca      300

tatctactaa tttatatgga ttatcctcgt tatttgggag cagtgtttcc tggaacaatg      360

tgtattactc gttattctgc aggagttgca ttgtacccca aggagataac tctggaggca      420

tttgcagtta ttgtcaccca gatgctggca ctcagtctgg gaatatcata tgacgaccca      480

aagaaatgtc aatgttcaga atccacctgt ataatgaatc cagaagttgt gcaatccaat      540

ggtgtgaaga cttttagcag ttgcagtttg aggagctttc aaaatttcat ttcaaatgtg      600

ggtgtcaaat gtcttcagaa taagccacaa atgcaaaaaa aatctccgaa accagtctgc      660

ggcaatggca gattggaggg aaatgaaatc tgtgattgtg gtactgaggc tcaatgtgga      720

cctgcaagct gttgtgattt tcgaacttgt gtactgaaag acggagcaaa atgttataaa      780

ggactgtgct gcaaagactg tcaaatttta caatcaggcg ttgaatgtag gccgaaagca      840

catcctgaat gtgacatcgc tgaaaattgt aatggaagct caccagaatg tggtcctgac      900

ataactttaa tcaatggact ttcatgcaaa aataataagt ttatttgtta tgacggagac      960

tgccatgatc tcgatgcacg ttgtgagagt gtatttggaa aaggttcaag aaatgctcca     1020

tttgcctgct atgaagaaat acaatctcaa tcagacagat ttgggaactg tggtagggat     1080

agaaataaca aatatgtgtt ctgtggatgg aggaatctta tatgtggaag attagtttgt     1140

acatacccta ctcgaaagcc tttccatcaa gaaaatggtg atgtgattta tgctttcgta     1200

cgagattctg tatgcataac tgtagactac aaattgcctc gaacagttcc agatccactg     1260

gctgtcaaaa atggctctca gtgtgatatt gggagggttt gtgtaaatcg tgaatgtgta     1320

gaatcaagga taattaaggc ttcagcacat gtttgttcac aacagtgttc tggacatgga     1380

gtgtgtgatt ccagaaacaa gtgccattgt tcgccaggct ataagcctcc aaactgccaa     1440

atacgttcca aaggattttc catatttcct gaggaagata tgggttcaat catggaaaga     1500

gcatctggga agactgaaaa cacc                                            1524


<210>  3112
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  3112
gaagcgcgca ggacccggaa gtacctggaa ctgtacattg tggcagacca caccctgttc       60

ttgactcggc accgaaactt gaaccacacc aaacagcgtc tcctggaagt cgccaactac      120

gtggaccagc ttctcaggac tctggacatt caggtggcgc tgaccggcct ggaggtgtgg      180

accgagcggg accgcagccg ccgccagctg cgcgccttct tccgcaaggg gggcggcgct      240

tgcctctcca atgccccgga ccccggactc ccggtgccgc cggcgctctg cgggaacggc      300

ttcgtggaag cgggcgagga gtgtgactgc ggccctggcc aggagtgccg cgacctctgc      360

tgctttgctc acaactgctc gctgcgcccg ggggcccagt gcgcccacgg ggactgctgc      420

gtgcgctgcc tgctgaagcc ggctggagcg ctgtgccgcc aggccatggg tgactgtgac      480

ctccctgagt tttgcacggg cacctcctcc cactgtcccc cagacgttta cctactggac      540

ggctcaccct gtgccagggg cagtggctac tgctgggatg gcgcatgtcc cacgctggag      600

cagcagtgcc agcagctctg ggggcctggc tcccacccag ctcccgaggc ctgtttccag      660

gtggtgaact ctgcgggaga tgctcatgga aactgcggcc aggacagcga gggccacttc      720

ctgccctgtg cagggaggga tgccctgtgt gggaagctgc agtgccaggg tggaaagccc      780

agcctgctcg caccgcacat ggtgccagtg gactctaccg ttcacctaga tggccaggaa      840

gtgacttgtc ggggagcctt ggcactcccc agtgcccagc tggacctgct tggcctgggc      900

ctggtagagc caggcaccca gtgtggacct agaatggtgt gccagagcag gcgctgcagg      960

aagaatgcct tccaggagct tcagcgctgc ctgactgcct gccacagcca cggggtttgc     1020

aatagcaacc ataactgcca ctgtgctcca ggctgggctc cacccttctg tgacaagcca     1080

ggctttggtg gcagcatgga cagtggccct gtgcaggctg aaaaccatga caccttcctg     1140

ctggccatgc tcctcagcgt cctgctgcct ctgctcccag gggccggcct ggcctggtgt     1200

tgctaccgac tcccaggagc ccatctgcag cgatgcagct ggggctgcag aagggaccct     1260

gcgtgcagtg gccccaaaga tggcccacac agggaccacc ccctgggcgg cgttcacccc     1320

atggagttgg gccccacagc cactggacag ccctggcccc tggaccctga gaactctcat     1380

gagcccagca gccaccctga gaagcctctg ccagcagtct cgcctgaccc ccaagatcaa     1440

gtccagatgc caagatcctg cctctgg                                         1467


<210>  3113
<211>  1917
<212>  DNA
<213>  Homo Sapiens

<400>  3113
attgccccca gccggccctg ggccctcatg gagcagtatg aggtcgtgtt gccgcggcgt       60

ctgccaggcc cccgagtccg ccgagctctg ccctcccact tgggcctgca cccagagagg      120

gtgagctacg tccttggggc cacagggcac aacttcaccc tccacctgcg gaagaacagg      180

gacctgctgg gttccggcta cacagagacc tatacggctg ccaatggctc cgaggtgacg      240

gagcagcctc gcgggcagga ccactgcttc taccagggcc acgtagaggg gtacccggac      300

tcagccgcca gcctcagcac ctgtgccggc ctcaggggtt tcttccaggt ggggtcagac      360

ctgcacctga tcgagcccct ggatgaaggt ggcgagggcg gacggcacgc cgtgtaccag      420

gctgagcacc tgctgcagac ggccgggacc tgcggggtca gcgacgacag cctgggcagc      480

ctcctgggac cccggacggc agccgtcttc aggcctcggc ccggggactc tctgccatcc      540

cgagagaccc gctacgtgga gctgtatgtg gtcgtggaca atgcagagtt ccagatgctg      600

gggagcgaag cagccgtgcg tcatcgggtg ctggaggtgg tgaatcacgt ggacaagcta      660

tatcagaaac tcaacttccg tgtggtcctg gtgggcctgg agatttggaa tagtcaggac      720

aggttccacg tcagccccga ccccagtgtc acactggaga acctcctgac ctggcaggca      780

cggcaacgga cacggcggca cctgcatgac aacgtacagc tcatcacggg tgtcgacttc      840

accgggacta ctgtggggtt tgccagggtg tccgccatgt gctcccacag ctcaggggct      900

gtgaaccagg accacagcaa gaaccccgtg ggcgtggcct gcaccatggc ccatgagatg      960

ggccacaacc tgggcatgga ccatgatgag aacgtccagg gctgccgctg ccaggaacgc     1020

ttcgaggccg gccgctgcat catggcaggc agcattggct ccagtttccc caggatgttc     1080

agtgactgca gccaggccta cctggagagc tttttggagc ggccgcagtc ggtgtgcctc     1140

gccaacgccc ctgacctcag ccacctggtg ggcggccccg tgtgtgggaa cctgtttgtg     1200

gagcgtgggg agcagtgcga ctgcggcccc cccgaggact gccggaaccg ctgctgcaac     1260

tctaccacct gccagctggc tgagggggcc cagtgtgcgc acggtacctg ctgccaggag     1320

tgcaaggtga agccggctgg tgagctgtgc cgtcccaaga aggacatgtg tgacctcgag     1380

gagttctgtg acggccggca ccctgagtgc ccggaagacg ccttccagga gaacggcacg     1440

ccctgctccg ggggctactg ctacaacggg gcctgtccca cactggccca gcagtgccag     1500

gccttctggg ggccaggtgg gcaggctgcc gaggagtcct gcttctccta tgacatccta     1560

ccaggctgca aggccagccg gtacagggct gacatgtgtg gcgttctgca gtgcaagggt     1620

gggcagcagc ccctggggcg tgccatctgc atcgtggatg tgtgccacgc gctcaccaca     1680

gaggatggca ctgcgtatga accagtgccc gagggcaccc ggtgtggacc agagaaggtt     1740

tgctggaaag gacgttgcca ggacttacac gtttacagat ccagcaactg ctctgcccag     1800

tgccacaacc atggggtgtg caaccacaag caggagtgcc actgccacgc gggctgggcc     1860

ccgccccact gcgcgaagct gctgactgag gtgcacgcag cgtccgggag cctcccc        1917


<210>  3114
<211>  888
<212>  DNA
<213>  Homo Sapiens

<400>  3114
gctgtcttgc cacagacccg gtatgtggag ctgttcattg tcgtagacaa ggaaaggtat       60

gacatgatgg gaagaaatca gactgctgtg agagaagaga tgattctcct ggcaaactac      120

ttggatagta tgtatattat gttaaatatt cgaattgtgc tagttggact ggagatttgg      180

accaatggaa acctgatcaa catagttggg ggtgctggtg atgtgctggg gaacttcgtg      240

cagtggcggg aaaagtttct tatcacacgt cggagacatg acagtgcaca gctagttcta      300

aagaaaggtt ttggtggaac tgcaggaatg gcatttgtgg gaacagtgtg ttcaaggagc      360

cacgcaggcg ggattaatgt gtttggacaa atcactgtgg agacatttgc ttccattgtt      420

gctcatgaat tgggtcataa tcttggaatg aatcacgatg atgggagaga ttgttcctgt      480

ggagcaaaga gctgcatcat gaattcagga gcatcgggtt ccagaaactt tagcagttgc      540

agtgcagagg actttgagaa gttaacttta aataaaggag gaaactgcct tcttaatatt      600

ccaaagcctg atgaagccta tagtgctccc tcctgtggta ataagttggt ggacgctggg      660

gaagagtgtg actgtggtac tccaaaggaa tgtgaattgg acccttgctg cgaaggaagt      720

acctgtaagc ttaaatcatt tgctgagtgt gcatatggtg actgttgtaa agactgtcgg      780

ttccttccag gaggtacttt atgccgagga aaaaccagtg agtgtgatgt tccagagtac      840

tgcaatggtt cttctcagtt ctgtcagcca gatgttttta ttcagaat                   888


<210>  3115
<211>  4995
<212>  DNA
<213>  Homo Sapiens

<400>  3115
gagaaatctc ctggagccta tttccttccc gagtttgcac tttctcctca gggaagtttt       60

ctggaagaca caacagggga gcagttcctc acttatcgct atgatgacca gacctcaaga      120

aacactcgtt cagatgaaga caaagatggc aactgggatg cttggggcga ctggagtgac      180

tgctcccgga cctgtggggg aggagcatca tattctctgc ggagatgttt gactggaagg      240

aattgtgaag ggcagaacat tcggtacaag acatgcagca atcatgactg ccctccagat      300

gcagaagatt tcagagccca gcagtgctca gcctacaatg atgtccagta tcaggggcgt      360

tactatgaat ggcttccacg atataatgat cctgctgccc cgtgtgcact caagtgtcat      420

gcacaaggac aaaacttggt ggtggagctg gcacctaagg tactggatgg aactcgttgc      480

aacacggact ccttggacat gtgtatcagt ggcatctgtc aggcagtggg ctgcgatcgg      540

caactgggaa gcaatgccaa ggaggacaac tgtggagtct gtgccggcga tggctccacc      600

tgcaggcttg tacggggaca atcaaagtca cacgtttctc ctgaaaaaag agaagaaaat      660

gtaattgctg ttcctttggg aagtcgaagt gtgagaatta cagtgaaagg acctgcccac      720

ctctttattg aatcaaaaac acttcaagga agcaaaggag aacacagctt taacagcccc      780

ggcgtctttg tcgtagaaaa cacaacagtg gaatttcaga ggggctccga gaggcaaact      840

tttaagattc caggacctct gatggctgat ttcatcttca agaccaggta cactgcagcc      900

aaagacagcg tggttcagtt cttcttttac cagcccatca gtcatcagtg gagacaaact      960

gacttctttc cctgcactgt gacgtgtgga ggaggttatc agctcaattc tgctgaatgt     1020

gtggatatcc gcttgaagag ggtagttcct gaccattatt gtcactacta ccctgaaaat     1080

gtaaaaccaa aaccaaaact gaaggaatgc agcatggatc cctgcccatc aagtgatgga     1140

tttaaagaga taatgcccta tgaccacttc caacctcttc ctcgctggga acataatcct     1200

tggactgcat gttccgtgtc ctgtggagga gggattcaga gacggagctt tgtgtgtgta     1260

gaggaatcca tgcatggaga gatattgcag gtggaagaat ggaagtgcat gtacgcaccc     1320

aaacccaagg ttatgcaaac ttgtaatctg tttgattgcc ccaagtggat tgccatggag     1380

tggtctcagt gcacagtgac ttgtggccga gggttacggt accgggttgt tctgtgtatt     1440

aaccaccgcg gagagcatgt tgggggctgc aatccacaac tgaagttaca catcaaagaa     1500

gaatgtgtca ttcccatccc gtgttataaa ccaaaagaaa aaagtccagt ggaagcaaaa     1560

ttgccttggc tgaaacaagc acaagaacta gaagagacca gaatagcaac agaagaacca     1620

acgttcattc cagaaccctg gtcagcctgc agtaccacgt gtgggccagg tgtgcaggtc     1680

cgcgaggtga agtgccgtgt gctcctcaca ttcacgcaga ctgagactga gctgcccgag     1740

gaagagtgtg aaggccccaa gctgcccacc gaacggccct gcctcctgga agcatgtgat     1800

gagagcccgg cctcccgaga gctagacatc cctctccctg aggacagtga gacgacttac     1860

gactgggagt acgctgggtt caccccttgc acagcaacat gcttgggagg ccatcaagaa     1920

gccatagcag tgtgcttaca tatccagacc cagcagacag tcaatgacag cttgtgtgat     1980

atggtccacc gtcctccagc catgagccag gcctgtaaca cagagccctg tccccccagg     2040

tggcatgtgg gctcttgggg gccctgctca gctacctgtg gagttggaat tcagacccga     2100

gatgtgtact gcctgcaccc aggggagacc cctgcccctc ctgaggagtg ccgagatgaa     2160

aagccccatg ctttacaagc atgcaatcag tttgactgcc ctcctggctg gcacattgaa     2220

gaatggcagc agtgttccag gacttgtggc gggggaactc agaacagaag agtcacctgt     2280

cggcagctgc taacggatgg cagctttttg aatctctcag atgaattgtg ccaaggaccc     2340

aaggcatcgt ctcacaagtc ctgtgccagg acagactgtc ctccacattt agctgtggga     2400

gactggtcga agtgttctgt cagttgtggt gttggaatcc agagaagaaa gcaggtgtgt     2460

caaaggctgg cagccaaagg tcggcgcatc cccctcagtg agatgatgtg cagggatcta     2520

ccagggctcc ctcttgtaag atcttgccag atgcctgagt gcagtaaaat caaatcagag     2580

atgaagacaa aacttggtga gcagggtccg cagatcctca gtgtccagag agtctacatt     2640

cagacaaggg aagagaagcg tattaacctg accattggta gcagagccta tttgctgccc     2700

aacacatccg tgattattaa gtgccccgtg cgacgattcc agaaatctct gatccagtgg     2760

gagaaggatg gccgttgcct gcagaactcc aaacggcttg gcatcaccaa gtcaggctca     2820

ctaaaaatcc acggtcttgc tgcccccgac atcggcgtgt accggtgcat tgcaggcttt     2880

gcacaggaaa cagttgtgct caagctcatt ggtactgaca accggctcat cgcacgccca     2940

gccctcaggg agcctatgag ggaatatcct gggatggacc acagcgaagc caatagtttg     3000

ggagtcacat ggcacaaaat gaggcaaatg tggaataaca aaaatgacct ttatctggat     3060

gatgaccaca ttagtaacca gcctttcttg agagctctgt taggccactg cagcaattct     3120

gcaggaagca ccaactcctg ggagttgaag aataagcagt ttgaagcagc agttaaacaa     3180

ggagcatata gcatggatac agcccagttt gatgagctga taagaaacat gagtcagctc     3240

atggaaaccg gagaggtcag cgatgatctt gcgtcccagc tgatatatca gctggtggcc     3300

gaattagcca aggcacagcc aacacacatg cagtggcggg gcatccagga agagacacct     3360

cctgctgctc agctcagagg ggaaacaggg agtgtgtccc aaagctcgca tgcaaaaaac     3420

tcaggcaagc tgacattcaa gccgaaagga cctgttctca tgaggcaaag ccaacctccc     3480

tcaatttcat ttaataaaac aataaattcc aggattggaa atacagtata cattacaaaa     3540

aggacagagg tcatcaatat actgtgtgac cttattaccc ccagtgaggc cacatataca     3600

tggaccaagg atggaacctt gttacagccc tcagtaaaaa taattttgga tggaactggg     3660

aagatacaga tacagaatcc tacaaggaaa gaacaaggca tatatgaatg ttctgtagct     3720

aatcatcttg gttcagatgt ggaaagttct tctgtgctgt atgcagaggc acctgtcatc     3780

ttgtctgttg aaagaaatat caccaaacca gagcacaacc atctgtctgt tgtggttgga     3840

ggcatcgtgg aggcagccct tggagcaaac gtgacaatcc gatgtcctgt aaaaggtgtc     3900

cctcagccta atataacttg gttgaagaga ggaggatctc tgagtggcaa tgtttccttg     3960

cttttcaatg gatccctgtt gttgcagaat gtttcccttg aaaatgaagg aacctacgtc     4020

tgcatagcca ccaatgctct tggaaaggca gtggcaacat ctgtactcca cttgctggaa     4080

cgaagatggc cagagagtag aatcgtattt ctgcaaggac ataaaaagta cattctccag     4140

gcaaccaaca ctagaaccaa cagcaatgac ccaacaggag aacccccgcc tcaagagcct     4200

ttttgggagc ctggtaactg gtcacattgt tctgccacct gtggtcattt gggagcccgc     4260

attcagagac cccagtgtgt gatggccaat gggcaggaag tgagtgaggc cctgtgtgat     4320

cacctccaga agccactggc tgggtttgag ccctgtaaca tccgggactg cccagcgagg     4380

tggttcacaa gtgtgtggtc acagtgctct gtgtcttgcg gtgaaggata ccacagtcgg     4440

caggtgacgt gcaagcggac aaaagccaat ggaactgtgc aggtggtgtc tccaagatca     4500

tgtgccccta aagaccggcc tctgggaaga aaaccatgtt ttggtcatcc atgtgttcag     4560

tgggaaccag ggaaccggtg tcctggacgt tgcatgggcc gtgctgtgag gatgcagcag     4620

cgtcacacag cttgtcaaca caacagctct gactccaact gtgatgacag aaagagaccc     4680

accttaagaa ggaactgcac atcaggggcc tgtgatgtgt gttggcacac aggcccttgg     4740

aagccctgta cagcagcctg tggcaggggt ttccagtctc ggaaagtcga ctgtatccac     4800

acaaggagtt gcaaacctgt ggccaagaga cactgtgtac agaaaaagaa accaatttcc     4860

tggcggcact gtcttgggcc ctcctgtgat agagactgca cagacacaac tcactactgt     4920

atgtttgtaa aacatcttaa tttgtgttct ctagaccgct acaaacaaag gtgctgccag     4980

tcatgtcaag aggga                                                      4995


<210>  3116
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  3116
caggactcca ggggctgtgc ccggtggtgc cctcaggact cctcgtgtgt caatgccacc       60

gcctgtcgct gcaatccagg gttcagctct ttttctgaga tcatcaccac ccccatggag      120

acttgtgacg acatcaacga gtgtgcaaca ctgtcgaaag tgtcatgcgg aaaattctcg      180

gactgctgga acacagaggg gagctacgac tgcgtgtgca gcccaggata tgagcctgtt      240

tctggggcaa aaacattcaa gaatgagagc gagaacacgt gtcaagatgt ggacgaatgt      300

cagcagaacc caaggctctg taaaagctac ggcacctgcg tcaacaccct tggcagctat      360

acctgccagt gcctgcctgg cttcaagttc atacctgagg atccgaaggt ctgcacagat      420

gtgaatgaat gcacctccgg acaaaaccca tgccacagct ccacccactg cctcaacaac      480

gtgggcagct atcagtgccg ctgccgcccg ggctggcaac cgattccggg gtcccccaat      540

ggcccaaaca ataccgtctg tgaagatgtg gacgagtgca gctccgggca gcatcagtgt      600

gacagctcca ccgtctgctt caacaccgtg ggttcataca gctgccgctg ccgcccaggc      660

tggaagccca gacacggaat cccgaataac caaaaggaca ctgtctgtga agatatgact      720

ttctccacct ggaccccgcc ccctggagtc cacagccaga cgctttcccg attcttcgac      780

aaagtccagg acctgggcag agactacaag ccaggcttgg ccaataacac catccagagc      840

atcttacagg cgctggatga gctgctggag gtccctgggg acctggagac cctgccccgc      900

ttacagcagc actgtgtggc cagtcacctg ctggatggcc tagaggatgt cctcagaggc      960

ctgagcaaga acctttccaa tgggctgttg aacttcagtt atcctgcagg cacagaattg     1020

tccctggagg tgcagaagca agtagacagg agtgtcacct tgagacagaa tcaggcagtg     1080

atgcagctcg actggaatca ggcacagaaa tctggtgacc caggcccttc tgtggtgggc     1140

cttgtctcca ttccagggat gggcaagttg ctggctgagg cccctctggt cctggaacct     1200

gagaagcaga tgcttctgca tgagacacac cagggcttgc tgcaggacgg ctcccccatc     1260

ctgctctcag atgtgatctc tgcctttctg agcaacaacg acacccaaaa cctcagctcc     1320

ccagttacct tcaccttctc ccaccgttca gtgatcccga gacagaaggt gctctgtgtc     1380

ttctgggagc atggccagaa tggatgtggt cactgggcca ccacaggctg cagcacaata     1440

ggcaccagag acaccagcac catctgccgt tgcacccacc tgagcagctt tgccgtcctc     1500

atggcccact acgatgtgca ggaggaggat cccgtgctga ctgtcatcac c              1551


<210>  3117
<211>  873
<212>  DNA
<213>  Homo Sapiens

<400>  3117
gacattaatg aatgtacacc accctatagt gtatattgtg gatttaacgc tgtgtgttac       60

aatgtcgaag gaagtttcta ctgtcaatgt gtcccaggat atagactgca ttctgggaat      120

gaacaattca gtaattccaa tgagaacacc tgtcaggaca ccacctcctc aaagacaacc      180

cagggcagga aagagctgca aaagattgtg gacaaatttg agtcacttct caccaatcag      240

actttatgga gaacagaagg gagacaagaa atctcatcca cagctaccac tattctccgg      300

gatgtggaat cgaaagttct agaaactgcc ttgaaagatc cagaacaaaa agtcctgaaa      360

atccaaaacg atagtgtagc tattgaaact caagcgatta cagacaattg ctctgaagaa      420

agaaagacat tcaacttgaa cgtccaaatg aactcaatgg acatccgttg cagtgacatc      480

atccagggag acacacaagg tcccagtgcc attgccttta tctcatattc ttctcttgga      540

aacatcataa atgcaacttt ttttgaagag atggataaga aagatcaagt gtatctgaac      600

tctcaggttg tgagtgctgc tattggaccc aaaaggaacg tgtctctctc caagtctgtg      660

acgctgactt tccagcacgt gaagatgacc cccagtacca aaaaggtctt ctgtgtctac      720

tggaagagca cagggcaggg cagccagtgg tccagggatg gctgcttcct gatacacgtg      780

aacaagagtc acaccatgtg taattgcagt cacctgtcca gcttcgctgt cctgatggcc      840

ctgaccagcc aggaggagga tcccgtgctg act                                   873


<210>  3118
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  3118
cccccttgtc caaaatacgc aagttgtcac aattccacac attgtacgtg cgaggatggt       60

tttagagcta gatctggaag aacgtatttt cacgacagca gcgaaaaatg cgaagacata      120

aacgagtgtg agacggggct ggcgaaatgt aaatacaagg cctattgtag aaataaggta      180

ggaggataca tttgcagctg ccttgttaag tatacacttt tcaattttct ggcaggtata      240

atagattatg accacccgga ttgttacgag aataacagtc aagggactac tcaaagcaat      300

gttgatatat gggtgagcgg ggtaaaaccg ggattcggga aacaattgcc aggcgataaa      360

cgtacaaaac atatttgcgt atactgggaa ggaagtgagg ggggttggag cacagaaggg      420

tgctcacacg tacatagtaa cggtagctac actaaatgca agtgtttcca tttgagttct      480

tttgcagtgc tggtcgcctt ggctcctaaa gaagaccccg tcttaaca                   528


<210>  3119
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  3119
gatgtggacg agtgcagctc cgggcagcat cagtgtgaca gctccaccgt ctgcttcaac       60

accgtgggtt catacagctg ccgctgccgc ccaggctgga agcccagaca cggaatcccg      120

aataaccaaa aggacactgt ctgtgaagat atgactttct ccacctggac cccgccccct      180

ggagtccaca gccagacgct ttcccgattc ttcgacaaag tccaggacct gggcagagac      240

tccaagacaa gctcagccga ggtcaccatc cagaatgtca tcaaattggt ggatgaactg      300

atggaagctc ctggagacgt agaggccctg gcgccacctg tccggcacct catagccacc      360

cagctgctct caaaccttga agatatcatg aggatcctgg ccaagagcct gcctaaaggc      420

cccttcacct acatttcccc ttcgaacaca gagctgaccc tgatgatcca ggagcggggg      480

gacaagaacg tcactatggg tcagagcagc gcacgcatga agctgaattg ggctgtggca      540

gctggagccg aggatccagg ccccgccgtg gcgggcatcc tctccatcca gaacatgacg      600

acattgctgg ccaatgcctc cttgaacctg cattccaaga agcaagccga actggaggag      660

atatatgaaa gcagcatccg tggtgtccaa ctcagacgcc tctctgccgt caactccatc      720

tttctgagcc acaacaacac caaggaactc aactccccca tccttttcgc cttctcccac      780

cttgagtcct ccgatgggga ggcgggaaga gaccctcctg ccaaggacgt gatgcctggg      840

ccacggcagg agctgctctg tgccttctgg aagagtgaca gcgacagggg agggcactgg      900

gccaccgagg gctgccaggt gctgggcagc aagaacggca gcaccacctg ccaatgcagc      960

cacctg                                                                 966


<210>  3120
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  3120
taccgccaga gcatgaacaa cttccagggc ctccggagct ttggctgccg cttcgggacg       60

tgcacggtgc agaagctggc acaccagatc taccagttca cagataagga caaggacaac      120

gtcgccccca ggagcaagat cagcccccag ggctac                                156


<210>  3121
<211>  141
<212>  DNA
<213>  Homo Sapiens

<400>  3121
acccaagccc agctcctgcg agtgggctgt gtgctgggca cctgccaggt gcagaatctc       60

agccaccgcc tgtggcaact catgggaccg gccggccggc aggactcagc tcctgtggac      120

cccagcagcc cccacagcta t                                                141


<210>  3122
<211>  960
<212>  DNA
<213>  Homo Sapiens

<400>  3122
gctcaaaaca tcacagcccg gattggcgag ccactggtgc tgaagtgtaa gggggccccc       60

aagaaaccac cccagcggct ggaatggaaa ctgaacacag gccggacaga agcttggaag      120

gtcctgtctc cccagggagg aggcccctgg gacagtgtgg ctcgtgtcct tcccaacggc      180

tccctcttcc ttccggctgt cgggatccag gatgagggga ttttccggtg ccaggcaatg      240

aacaggaatg gaaaggagac caagtccaac taccgagtcc gtgtctacca gattcctggg      300

aagccagaaa ttgtagattc tgcctctgaa ctcacggctg gtgttcccaa taaggtgggg      360

acatgtgtgt cagagggaag ctaccctgca gggactctta gctggcactt ggatgggaag      420

cccctggtgc ctaatgagaa gggagtatct gtgaaggaac agaccaggag acaccctgag      480

acagggctct tcacactgca gtcggagcta atggtgaccc cagcccgggg aggagatccc      540

cgtcccacct tctcctgtag cttcagccca ggccttcccc gacaccgggc cttgcgcaca      600

gcccccatcc agccccgtgt ctgggagcct gtgcctctgg aggaggtcca attggtggtg      660

gagccagaag gtggagcagt agctcctggt ggaaccgtaa ccctgacctg tgaagtccct      720

gcccagccct ctcctcaaat ccactggatg aaggatggtg tgcccttgcc ccttcccccc      780

agccctgtgc tgatcctccc tgagataggg cctcaggacc agggaaccta cagctgtgtg      840

gccacccatt ccagccacgg gccccaggaa agccgtgctg tcagcatcag catcatcgaa      900

ccaggcgagg aggggccaac tgcaggctct gtgggaggat cagggctggg aactctagcc      960


<210>  3123
<211>  1296
<212>  DNA
<213>  Homo Sapiens

<400>  3123
tgccgctttg gagccctgtg cgaggccgag accgggcgct gcgtgtgccc ctctgaatgc       60

gtggctttgg cccagcccgt gtgtggctcc gacgggcaca cgtaccccag cgagtgcatg      120

ctgcacgtgc acgcctgcac acaccagatc agcctgcacg tggcctcagc tggaccctgt      180

gagacctgtg gagatgccgt gtgtgctttt ggggctgtgt gctccgcagg gcagtgtgtg      240

tgtccccggt gtgagcaccc cccgcccggc cccgtgtgtg gcagcgacgg tgtcacctac      300

ggcagtgcct gcgagctacg ggaagccgcc tgcctccagc agacacagat cgaggaggcc      360

cgggcagggc cgtgcgagca ggccgagtgc ggttccggag gctctggctc tggggaggac      420

ggtgactgtg agcaggagct gtgccggcag cgcggtggca tctgggacga ggactcggag      480

gacgggccgt gtgtctgtga cttcagctgc cagagtgtcc caggcagccc ggtgtgcggc      540

tcagatgggg tcacctacag caccgagtgt gagctgaaga aggccaggtg tgagtcacag      600

cgagggctct acgtagcggc ccagggagcc tgccgaggcc ccaccttcgc cccgctgccg      660

cctgtggccc ccttacactg tgcccagacg ccctacggct gctgccagga caatatcacc      720

gcagcccggg gcgtgggcct ggctggctgc cccagtgcct gccagtgcaa cccccatggc      780

tcttacggcg gcacctgtga cccagccaca ggccagtgct cctgccgccc aggtgtgggg      840

ggcctcaggt gtgaccgctg tgagcctggc ttctggaact ttcgaggcat cgtcaccgat      900

ggccggagtg gctgtacacc ctgcagctgt gatccccaag gcgccgtgcg ggatgactgt      960

gagcagatga cggggctgtg ctcgtgtaag cccggggtgg ctggacccaa gtgtgggcag     1020

tgtccagacg gccgtgccct gggccccgcg ggctgtgaag ctgacgcttc tgcgcctgcg     1080

acctgtgcgg agatgcgctg tgagttcggt gcgcggtgcg tggaggagtc tggctcagcc     1140

cactgtgtct gcccgatgct cacctgtcca gaggccaacg ctaccaaggt ctgtgggtca     1200

gatggagtca catacggcaa cgagtgtcag ctgaagacca tcgcctgccg ccagggcctg     1260

caaatctcta tccagagcct gggcccgtgc caggag                               1296


<210>  3124
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  3124
tggtatactg taaattcagc atatggagat accattatca taccttgccg acttgacgta       60

cctcagaatc tcatgtttgg caaatggaaa tatgaaaagc ccgatggctc cccagtattt      120

attgccttca gatcctctac aaagaaaagt gtgcagtacg acgatgtacc agaatacaaa      180

gacagattga acctctcaga aaactacact ttgtctatca gtaatgcaag gatcagtgat      240

gaaaagagat ttgtgtgcat gctagtaact gaggacaacg tgtttgaggc acctacaata      300

gtcaaggtgt tcaagcaacc atctaaacct gaaattgtaa gcaaagcact gtttctcgaa      360

acagagcagc taaaaaagtt gggtgactgc atttcagaag acagttatcc agatggcaat      420

atcacatggt acaggaatgg aaaagtgcta catccccttg aaggagcggt ggtcataatt      480

tttaaaaagg aaatggaccc agtgactcag ctctatacca tgacttccac cctggagtac      540

aagacaacca aggctgacat acaaatgcca ttcacctgct cggtgacata ttatggacca      600

tctggccaga aaacaattca ttctgaacag gcagtatttg atatttacta tcctacagag      660

caggtgacaa tacaagtgct gccaccaaaa aatgccatca aagaagggga taacatcact      720

cttaaatgct tagggaatgg caaccctccc ccagaggaat ttttgtttta cttaccagga      780

cagcccgaag gaataagaag ctcaaatact tacacactaa cggatgtgag gcgcaatgca      840

acaggagact acaagtgttc cctgatagac aaaaaaagca tgattgcttc aacagccatc      900

acagttcact atttggattt gtccttaaac ccaagtggag aagtgactag acagattggt      960

gatgccctac ccgtgtcatg cacaatatct gctagcagga atgcaactgt ggtatggatg     1020

aaagataaca tcaggcttcg atctagcccg tcattttcta gtcttcatta tcaggatgct     1080

ggaaactatg tctgcgaaac tgctctgcag gaggttgaag gactaaagaa aagagagtca     1140

ttgactctca ttgtagaagg caaacctcaa ataaaaatga caaaaaaaac tgatcccagt     1200

ggactatcta aaacaataat ctgccatgtg gaaggttttc caaagccagc cattcaatgg     1260

acaattactg gcagtggaag cgtcataaac caaacagagg aatctcctta tattaatggc     1320

aggtattata gtaaaattat catttcccct gaagagaatg ttacattaac ttgcacagca     1380

gaaaaccaac tggagagaac agtaaactcc ttgaatgtct ctgctataag tattccagaa     1440

cacgatgagg cagacgagat aagtgatgaa aacagagaaa aggtgaatga ccaggcaaaa     1500


<210>  3125
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  3125
ctgaatgact tgaatgtttc cccgcctgag ctaacagtcc atgtgggtga ttcagctctg       60

atgggatgtg ttttccagag cacagaagac aaatgtatat tcaagataga ctggactctg      120

tcaccaggag agcacgccaa ggacgaatat gtgctatact attactccaa tctcagtgtg      180

cctattgggc gcttccagaa ccgcgtacac ttgatggggg acatcttatg caatgatggc      240

tctctcctgc tccaagatgt gcaagaggct gaccagggaa cctatatctg tgaaatccgc      300

ctcaaagggg agagccaggt gttcaagaag gcggtggtac tgcatgtgct tccagaggag      360

cccaaagagc tcatggtcca tgtgggtgga ttgattcaga tgggatgtgt tttccagagc      420

acagaagtga aacacgtgac caaggtagaa tggatatttt caggacggcg cgcaaaggag      480

gagattgtat ttcgttacta ccacaaactc aggatgtctg tggagtactc ccagagctgg      540

ggccacttcc agaatcgtgt gaacctggtg ggggacattt tccgcaatga cggttccatc      600

atgcttcaag gagtgaggga gtcagatgga ggaaactaca cctgcagtat ccacctaggg      660

aacctggtgt tcaagaaaac cattgtgctg catgtcagcc cggaagagcc tcgaacactg      720

gtgaccccgg cagccctgag gcctctggtc ttgggtggta atcagttg                   768


<210>  3126
<211>  1035
<212>  DNA
<213>  Homo Sapiens

<400>  3126
ggccgagccg tggttagctg tcctgccgcc tgcttgtgcg ccagcaacat cctcagctgc       60

tccaagcagc agctgcccaa tgtgccccat tccctgccca gttacacagc actactggac      120

ctcagtcaca acaacctgag ccgcctgcgg gccgagtgga cccccacgcg cctgacccaa      180

ctgcactccc tgctgctgag ccacaaccac ctgaacttca tctcctctga ggccttttcc      240

ccggtaccca acctgcgcta cctggacctc tcctccaacc agctgcgtac actggatgag      300

ttcctgttca gtgacctgca agtactggag gtgctgctgc tctacaataa ccacatcatg      360

gcggtggacc ggtgcgcctt cgatgacatg gcccagctgc agaaactcta cttgagccag      420

aaccagatct ctcgcttccc tctggaactg gtcaaggaag gagccaagct acccaaacta      480

acgctcctgg atctctcttc taacaagctg aagaacttgc cattgcctga cctgcagaag      540

ctgccggcct ggatcaagaa tgggctgtac ctacataaca accccctgaa ctgcgactgt      600

gagctctacc agctgttttc acactggcag tatcggcagc tgagctccgt gatggacttt      660

caagaggatc tgtactgcat gaactccaag aagctgcaca atgtcttcaa cctgagtttc      720

ctcaactgtg gcgagtacaa ggagcgtgcc tgggaggccc acctgggtga caccttgatc      780

atcaagtgtg acaccaagca gcaagggatg accaaggtgt gggtgacacc aagtaatgaa      840

cgggtgctag atgaggtgac caatggcaca gtgagtgtgt ctaaggatgg cagtcttctt      900

ttccagcagg tgcaggtcga ggacggtggt gtgtatacct gctatgccat gggagagact      960

ttcaatgaga cactgtctgt ggaattgaaa gtgcacaatt tcaccttgca cggacaccat     1020

gacaccctca acaca                                                      1035


<210>  3127
<211>  1077
<212>  DNA
<213>  Homo Sapiens

<400>  3127
gtgtgcccca ccgcttgcat ctgtgccact gacatcgtca gctgcaccaa caaaaacctg       60

tccaaggtgc ctgggaacct tttcagactg attaagagac tggacctgag ttataacaga      120

attgggcttc tggattctga gtggattcca gtatcgtttg caaagctgaa caccctaatt      180

cttcgtcata acaacatcac cagcatttcc acgggcagtt tttccacaac tccaaatttg      240

aagtgtcttg acttatcgtc caataagctg aagacggtga aaaatgctgt attccaagag      300

ttgaaggttc tggaagtgct tctgctttac aacaatcaca tatcctatct cgatccttca      360

gcgtttggag ggctctccca gttgcagaaa ctctacttaa gtggaaattt tctcacacag      420

tttccgatgg atttgtatgt tggaaggttc aagctggcag aactgatgtt tttagatgtt      480

tcttataacc gaattccttc catgccaatg caccacataa atttagtgcc aggaaaacag      540

ctgagaggca tctaccttca tggaaaccca tttgtctgtg actgttccct gtactccttg      600

ctggtctttt ggtatcgtag gcactttagc tcagtgatgg attttaagaa cgattacacc      660

tgtcgcctgt ggtctgactc caggcactcg cgtcaggtac ttctgctcca ggatagcttt      720

atgaattgct ctgacagcat catcaatggt tcctttcgtg cgcttggctt tattcatgag      780

gctcaggtcg gggaaagact gatggtccac tgtgacagca agacaggtaa tgcaaatacg      840

gatttcatct gggtgggtcc agataacaga ctgctagagc cggataaaga gatggaaaac      900

ttttacgtgt ttcacaatgg aagtctggtt atagaaagcc ctcgttttga ggatgctgga      960

gtgtattctt gtatcgcaat gaataagcaa cgcctgttaa atgaaactgt ggacgtcaca     1020

ataaatgtga gcaatttcac tgtaagcaga tcccatgctc atgaggcatt taacaca        1077


<210>  3128
<211>  1092
<212>  DNA
<213>  Homo Sapiens

<400>  3128
accccggact ccgagggttt cccgccccgt gcgctccaca actgccccta caaatgtatc       60

tgcgctgccg acctgctaag ctgcactggc ctagggctgc aggacgtgcc agccgagtta      120

cctgccgcta ctgcggacct cgacctgagc cacaacgcgc tccagcgcct gcgccccggc      180

tggttggcgc ccctcttcca gctgcgcgcc ctgcacctag accacaacga actagatgcg      240

ctgggtcgcg gcgtcttcgt caacgccagc ggcctgaggc tgctcgatct atcatctaac      300

acgttgcggg cgcttggccg ccacgacctc gacgggctgg gggcgctgga gaagctgctt      360

ctgttcaata accgcttggt gcacttggac gagcatgcct tccacggcct gcgcgcgctc      420

agccatctct acctgggctg caacgaactc gcctcgttct ccttcgacca cctgcacggt      480

ctgagcgcca cccacctgct tactctggac ctctcctcca accggctggg acacatctcc      540

gtacctgagc tggccgcgct gccggccttc ctcaagaacg gcctctactt gcacaacaac      600

cctttgcctt gcgactgccg cctctaccac ctgctacagc gctggcacca gcggggcctg      660

agcgccgtgc gcgactttgc gcgcgagtac gtatgcttgg ccttcaaggt acccgcgtcc      720

cgcgtgcgct tcttccagca cagccgcgtc tttgagaact gctcgtcggc cccagctctt      780

ggcctagagc ggccggaaga gcacctgtac gcgctggtgg gtcggtccct gaggctttac      840

tgcaacacca gcgtcccggc catgcgcatt gcctgggttt cgccgcagca ggagcttctc      900

agggcgccag gatcccgcga tggcagcatc gcggtgctgg ccgacggcag cttggccata      960

ggcaacgtac aggagcagca tgcgggactc ttcgtgtgcc tggccactgg gccccgcctg     1020

caccacaacc agacgcacga gtacaacgtg agcgtgcact ttccgcgccc agagcccgag     1080

gctttcaaca ca                                                         1092


<210>  3129
<211>  1449
<212>  DNA
<213>  Homo Sapiens

<400>  3129
cacatagggt gcagcaatca gcgccgaagt ccagaaaaca gtgggagaag atataaccgg       60

attcaacatg ggcaatgtgc ctacactttc attcttccag aacacgatgg caactgtcgt      120

gagagtacga cagaccagta caacacaaac gctctgcaga gagatgctcc acacgtggaa      180

ccggatttct cttcccagaa acttcaacat ctggaacatg tgatggaaaa ttatactcag      240

tggctgcaaa aacttgagaa ttacattgtg gaaaacatga agtcggagat ggcccagata      300

cagcagaatg cagttcagaa ccacacggct accatgctgg agataggaac cagcctcctc      360

tctcagactg cagagcagac cagaaagctg acagatgttg agacccaggt actaaatcaa      420

acttctcgac ttgagataca gctgctggag aattcattat ccacctacaa gctagagaag      480

caacttcttc aacagacaaa tgaaatcttg aagatccatg aaaaaaacag tttattagaa      540

cataaaatct tagaaatgga aggaaaacac aaggaagagt tggacacctt aaaggaagag      600

aaagagaacc ttcaaggctt ggttactcgt caaacatata taatccagga gctggaaaag      660

caattaaaca gagctaccac caacaacagt gtccttcaga agcagcaact ggagctgatg      720

gacacagtcc acaaccttgt caatctttgc actaaagaag gtgttttact aaagggagga      780

aaaagagagg aagagaaacc atttagagac tgtgcagatg tatatcaagc tggttttaat      840

aaaagtggaa tctacactat ttatattaat aatatgccag aacccaaaaa ggtgttttgc      900

aatatggatg tcaatggggg aggttggact gtaatacaac atcgtgaaga tggaagtcta      960

gatttccaaa gaggctggaa ggaatataaa atgggttttg gaaatccctc cggtgaatat     1020

tggctgggga atgagtttat ttttgccatt accagtcaga ggcagtacat gctaagaatt     1080

gagttaatgg actgggaagg gaaccgagcc tattcacagt atgacagatt ccacatagga     1140

aatgaaaagc aaaactatag gttgtattta aaaggtcaca ctgggacagc aggaaaacag     1200

agcagcctga tcttacacgg tgctgatttc agcactaaag atgctgataa tgacaactgt     1260

atgtgcaaat gtgccctcat gttaacagga ggatggtggt ttgatgcttg tggcccctcc     1320

aatctaaatg gaatgttcta tactgcggga caaaaccatg gaaaactgaa tgggataaag     1380

tggcactact tcaaagggcc cagttactcc ttacgttcca caactatgat gattcgacct     1440

ttagatttt                                                             1449


<210>  3130
<211>  1434
<212>  DNA
<213>  Homo Sapiens

<400>  3130
tataacaact ttcggaagag catggacagc ataggaaaga agcaatatca ggtccagcat       60

gggtcctgca gctacacttt cctcctgcca gagatggaca actgccgctc ttcctccagc      120

ccctacgtgt ccaatgctgt gcagagggac gcgccgctcg aatacgatga ctcggtgcag      180

aggctgcaag tgctggagaa catcatggaa aacaacactc agtggctaat gaagcttgag      240

aattatatcc aggacaacat gaagaaagaa atggtagaga tacagcagaa tgcagtacag      300

aaccagacgg ctgtgatgat agaaataggg acaaacctgt tgaaccaaac agcggagcaa      360

acgcggaagt taactgatgt ggaagcccaa gtattaaatc agaccacgag acttgaactt      420

cagctcttgg aacactccct ctcgacaaac aaattggaaa aacagatttt ggaccagacc      480

agtgaaataa acaaattgca agataagaac agtttcctag aaaagaaggt gctagctatg      540

gaagacaagc acatcatcca actacagtca ataaaagaag agaaagatca gctacaggtg      600

ttagtatcca agcaaaattc catcattgaa gaactagaaa aaaaaatagt gactgccacg      660

gtgaataatt cagttcttca aaagcagcaa catgatctca tggagacagt taataactta      720

ctgactatga tgtccacatc aaactcagct aaggacccca ctgttgctaa agaagaacaa      780

atcagcttca gagactgtgc tgaagtattc aaatcaggac acaccacgaa tggcatctac      840

acgttaacat tccctaattc tacagaagag atcaaggcct actgtgacat ggaagctgga      900

ggaggcgggt ggacaattat tcagcgacgt gaggatggca gcgttgattt tcagaggact      960

tggaaagaat ataaagtggg atttggtaac ccttcaggag aatattggct gggaaatgag     1020

tttgtttcgc aactgactaa tcagcaacgc tacgtgctta aaatacacct taaagactgg     1080

gaagggaatg aggcttactc attgtatgaa catttctatc tctcaagtga agaactcaat     1140

tataggattc accttaaagg acttacaggg acagccggca aaataagcag catcagccaa     1200

ccaggaaatg attttagcac aaaggatgga gacaacgaca aatgtatttg caaatgttca     1260

caaatgctaa caggaggctg gtggtttgat gcatgtggtc cttccaactt gaacggaatg     1320

tactatccac agaggcagaa cacaaataag ttcaacggca ttaaatggta ctactggaaa     1380

ggctcaggct attcgctcaa ggccacaacc atgatgatcc gaccagcaga tttc           1434


<210>  3131
<211>  1437
<212>  DNA
<213>  Homo Sapiens

<400>  3131
acaaggcagg aggcggatag gggctgcgag acacttgtag tccagcacgg ccactgtagc       60

tacaccttct tgctgcccaa gtctgagccc tgccctccgg ggcctgaggt ctccagggac      120

tccaacaccc tccagagaga atcactggcc aacccactgc acctggggaa gttgcccacc      180

cagcaggtga aacagctgga gcaggcactg cagaacaaca cgcagtggct gaagaagcta      240

gagagggcca tcaagacgat cttgaggtcg aagctggagc aggtccagca gcaaatggcc      300

cagaatcaga cggcccccat gctagagctg ggcaccagcc tcctgaacca gaccactgcc      360

cagatccgca agctgaccga catggaggct cagctcctga accagacatc aagaatggat      420

gcccagatgc cagagacctt tctgtccacc aacaagctgg agaaccagct gctgctacag      480

aggcagaagc tccagcagct tcagggccaa aacagcgcgc tggagaagcg gttgcaggcc      540

ctggagacca agcagcagga ggagctggcc agcatcctca gcaagaaggc gaagctgctg      600

aacacgctga gccgccagag cgccgccctc accaacatcg agcgcggcct gcgcggtgtc      660

aggcacaact ccagcctcct gcaggaccag cagcacagcc tgcgccagct gctggtgttg      720

ttgcggcacc tggtgcaaga aagggctaac gcctcggccc cggccttcat aatggcaggt      780

gagcaggtgt tccaggactg tgcagagatc cagcgctctg gggccagtgc cagtggtgtc      840

tacaccatcc aggtgtccaa tgcaacgaag cccaggaagg tgttctgtga cctgcagagc      900

agtggaggca ggtggaccct catccagcgc cgtgagaatg gcaccgtgaa ttttcagcgg      960

aactggaagg attacaaaca gggcttcgga gacccagctg gggagcactg gctgggcaat     1020

gaagtggtgc accagctcac cagaagggca gcctactctc tgcgtgtgga gctgcaagac     1080

tgggaaggcc acgaggccta tgcccagtac gaacatttcc acctgggcag tgagaaccag     1140

ctatacaggc tttctgtggt cgggtacagc ggctcagcag ggcgccagag cagcctggtc     1200

ctgcagaaca ccagctttag cacccttgac tcagacaacg accactgtct ctgcaagtgt     1260

gcccaagtga tgtctggagg gtggtggttt gacgcctgtg gcctgtcaaa cctcaacggc     1320

gtctactacc acgctcccga caacaagtac aagatggacg gcatccgctg gcactacttc     1380

aagggcccca gctactcact gcgtgcctct cgcatgatga tacggccttt ggacatc        1437


<210>  3132
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  3132
caggaggacg gttttgaggg cactgaggag ggctcgccaa gagagttcat ttacctaaac       60

aggtacaagc gggcgggcga gtcccaggac aagtgcacct acaccttcat tgtgccccag      120

cagcgggtca cgggtgccat ctgcgtcaac tccaaggagc ctgaggtgct tctggagaac      180

cgagtgcata agcaggagct agagctgctc aacaatgagc tgctcaagca gaagcggcag      240

atcgagacgc tgcagcagct ggtggaggtg gacggcggca ttgtgagcga ggtgaagctg      300

ctgcgcaagg agagccgcaa catgaactcg cgggtcacgc agctctacat gcagctcctg      360

cacgagatca tccgcaagcg ggacaacgcg ttggagctct cccagctgga gaacaggatc      420

ctgaaccaga cagccgacat gctgcagctg gccagcaagt acaaggacct ggagcacaag      480

taccagcacc tggccacact ggcccacaac caatcagaga tcatcgcgca gcttgaggag      540

cactgccaga gggtgccctc ggccaggccc gtcccccagc caccccccgc tgccccgccc      600

cgggtctacc aaccacccac ctacaaccgc atcatcaacc agatctctac caacgagatc      660

cagagtgacc agaacctgaa ggtgctgcca ccccctctgc ccactatgcc cactctcacc      720

agcctcccat cttccaccga caagccgtcg ggcccatgga gagactgcct gcaggccctg      780

gaggatggcc acgacaccag ctccatctac ctggtgaagc cggagaacac caaccgcctc      840

atgcaggtgt ggtgcgacca gagacacgac cccgggggct ggaccgtcat ccagagacgc      900

ctggatggct ctgttaactt cttcaggaac tgggagacgt acaagcaagg gtttgggaac      960

attgacggcg aatactggct gggcctggag aacatttact ggctgacgaa ccaaggcaac     1020

tacaaactcc tggtgaccat ggaggactgg tccggccgca aagtctttgc agaatacgcc     1080

agtttccgcc tggaacctga gagcgagtat tataagctgc ggctggggcg ctaccatggc     1140

aatgcgggtg actcctttac atggcacaac ggcaagcagt tcaccaccct ggacagagat     1200

catgatgtct acacaggaaa ctgtgcccac taccagaagg gaggctggtg gtataacgcc     1260

tgtgcccact ccaacctcaa cggggtctgg taccgcgggg gccattaccg gagccgctac     1320

caggacggag tctactgggc tgagttccga ggaggctctt actcactcaa gaaagtggtg     1380

atgatgatcc gaccgaaccc caacaccttc cac                                  1413


<210>  3133
<211>  1332
<212>  DNA
<213>  Homo Sapiens

<400>  3133
tccagaattg atcaagacaa ttcatcattt gattctctat ctccagagcc aaaatcaaga       60

tttgctatgt tagacgatgt aaaaatttta gccaatggcc tccttcagtt gggacatggt      120

cttaaagact ttgtccataa gacgaagggc caaattaatg acatatttca aaaactcaac      180

atatttgatc agtcttttta tgatctatcg ctgcaaacca gtgaaatcaa agaagaagaa      240

aaggaactga gaagaactac atataaacta caagtcaaaa atgaagaggt aaagaatatg      300

tcacttgaac tcaactcaaa acttgaaagc ctcctagaag aaaaaattct acttcaacaa      360

aaagtgaaat atttagaaga gcaactaact aacttaattc aaaatcaacc tgaaactcca      420

gaacacccag aagtaacttc acttaaaact tttgtagaaa aacaagataa tagcatcaaa      480

gaccttctcc agaccgtgga agaccaatat aaacaattaa accaacagca tagtcaaata      540

aaagaaatag aaaatcagct cagaaggact agtattcaag aacccacaga aatttctcta      600

tcttccaagc caagagcacc aagaactact ccctttcttc agttgaatga aataagaaat      660

gtaaaacatg atggcattcc tgctgaatgt accaccattt ataacagagg tgaacataca      720

agtggcatgt atgccatcag acccagcaac tctcaagttt ttcatgtcta ctgtgatgtt      780

atatcaggta gtccatggac attaattcaa catcgaatag atggatcaca aaacttcaat      840

gaaacgtggg agaactacaa atatggtttt gggaggcttg atggagaatt ttggttgggc      900

ctagagaaga tatactccat agtgaagcaa tctaattatg ttttacgaat tgagttggaa      960

gactggaaag acaacaaaca ttatattgaa tattcttttt acttgggaaa tcacgaaacc     1020

aactatacgc tacatctagt tgcgattact ggcaatgtcc ccaatgcaat cccggaaaac     1080

aaagatttgg tgttttctac ttgggatcac aaagcaaaag gacacttcaa ctgtccagag     1140

ggttattcag gaggctggtg gtggcatgat gagtgtggag aaaacaacct aaatggtaaa     1200

tataacaaac caagagcaaa atctaagcca gagaggagaa gaggattatc ttggaagtct     1260

caaaatggaa ggttatactc tataaaatca accaaaatgt tgatccatcc aacagattca     1320

gaaagctttg aa                                                         1332


<210>  3134
<211>  1143
<212>  DNA
<213>  Homo Sapiens

<400>  3134
ggacccgtgc agtccaagtc gccgcgcttt gcgtcctggg acgagatgaa tgtcctggcg       60

cacggactcc tgcagctcgg ccaggggctg cgcgaacacg cggagcgcac ccgcagtcag      120

ctgagcgcgc tggagcggcg cctgagcgcg tgcgggtccg cctgtcaggg aaccgagggg      180

tccaccgacc tcccgttagc ccctgagagc cgggtggacc ctgaggtcct tcacagcctg      240

cagacacaac tcaaggctca gaacagcagg atccagcaac tcttccacaa ggtggcccag      300

cagcagcggc acctggagaa gcagcacctg cgaattcagc atctgcaaag ccagtttggc      360

ctcctggacc acaagcacct agaccatgag gtggccaagc ctgcccgaag aaagaggctg      420

cccgagatgg cccagccagt tgacccggct cacaatgtca gccgcctgca ccggctgccc      480

agggattgcc aggagctgtt ccaggttggg gagaggcaga gtggactatt tgaaatccag      540

cctcaggggt ctccgccatt tttggtgaac tgcaagatga cctcagatgg aggctggaca      600

gtaattcaga ggcgccacga tggctcagtg gacttcaacc ggccctggga agcctacaag      660

gcggggtttg gggatcccca cggcgagttc tggctgggtc tggagaaggt gcatagcatc      720

acgggggacc gcaacagccg cctggccgtg cagctgcggg actgggatgg caacgccgag      780

ttgctgcagt tctccgtgca cctgggtggc gaggacacgg cctatagcct gcagctcact      840

gcacccgtgg ccggccagct gggcgccacc accgtcccac ccagcggcct ctccgtaccc      900

ttctccactt gggaccagga tcacgacctc cgcagggaca agaactgcgc caagagcctc      960

tctggaggct ggtggtttgg cacctgcagc cattccaacc tcaacggcca gtacttccgc     1020

tccatcccac agcagcggca gaagcttaag aagggaatct tctggaagac ctggcggggc     1080

cgctactacc cactgcaggc caccaccatg ttgatccagc ccatggcagc agaggcagcc     1140

tcc                                                                   1143


<210>  3135
<211>  903
<212>  DNA
<213>  Homo Sapiens

<400>  3135
gaggatgggg gtccagcctg ctacggcgga tttgacctgt acttcatttt ggacaaatca       60

ggaagtgtgc tgcaccactg gaatgaaatc tattactttg tggaacagtt ggctcacaaa      120

ttcatcagcc cacagttgag aatgtccttt attgttttct ccacccgagg aacaacctta      180

atgaaactga cagaagacag agaacaaatc cgtcaaggcc tagaagaact ccagaaagtt      240

ctgccaggag gagacactta catgcatgaa ggatttgaaa gggccagtga gcagatttat      300

tatgaaaaca gacaagggta caggacagcc agcgtcatca ttgctttgac tgatggagaa      360

ctccatgaag atctcttttt ctattcagag agggaggcta ataggtctcg agatcttggt      420

gcaattgttt actgtgttgg tgtgaaagat ttcaatgaga cacagctggc ccggattgcg      480

gacagtaagg atcatgtgtt tcccgtgaat gacggctttc aggctctgca aggcatcatc      540

cactcaattt tgaagaagtc ctgcatcgaa attctagcag ctgaaccatc caccatatgt      600

gcaggagagt catttcaagt tgtcgtgaga ggaaacggct tccgacatgc ccgcaacgtg      660

gacagggtcc tctgcagctt caagatcaat gactcggtca cactcaatga gaagcccttt      720

tctgtggaag atacttattt actgtgtcca gcgcctatct taaaagaagt tggcatgaaa      780

gctgcactcc aggtcagcat gaacgatggc ctctctttta tctccagttc tgtcatcatc      840

accaccacac actgtagcct ccacaaaatt gcatcaggcc ccacaacagc tgcttgcatg      900

gaa                                                                    903


<210>  3136
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  3136
caggaacaac cttcatgcag gcgtgccttt gatttgtatt tcgtcctgga caagtccgga       60

tctgttgcga ataattggat agagatctac aattttgttc agcaattggc agaacgtttt      120

gtaagtccgg aaatgcgtct ttccttcatc gtattctcaa gtcaagcaac tattattctt      180

ccactgacgg gggacagggg taaaatctca aagggacttg aagacttaaa aagggtatcc      240

ccagtgggcg agacttatat ccatgagggc ctgaaattag caaacgagca gattcagaaa      300

gcgggtggcc taaaaacttc aagtatcatt attgccctaa ccgacggaaa attggacggt      360

cttgtaccgt catatgcaga gaaagaggca aagattagca ggtccctggg agcaagtgtt      420

tattgtgtag gcgtattaga cttcgagcag gcacagctag agaggattgc tgatagcaaa      480

gaacaggttt ttcctgtgaa ggggggtttc caggcgttaa aggggataat caatagtatt      540

ctagcacaga gctgtacgga gatattggaa cttcaaccta gtagcgtctg cgtcggtgag      600

gagtttcaga ttgtattatc agggaggggg tttatgctag ggagtcgtaa tggttctgtc      660

ttgtgtacct atactgtgaa cgagacctac acgacatcag ttaaacctgt gtccgtccag      720

ctaaacagta tgctttgccc cgcaccaatc ctgaacaaag ccggcgagac actagacgtg      780

agtgtatcat tcaatggtgg aaaaagtgtt attagcgggt ccctgatagt cactgcaact      840

gaatgtagta acggg                                                       855


<210>  3137
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  3137
ggctctttgc gttaccatgg tcccgactgg agaatcttcc accgtctagc tttgggttcc       60

agaagggcgc atcatcatca tggccccgga tggcgtcagc actggaggca aggacaagcg      120

ggacacagat gccagggcag tttcgacctt tatttcatcc ttgataagtc tgggtcagta      180

aacaacaact ggattgatct gtatatgtgg gttgaggaga cagttgcaag gtttcagagt      240

cccaacataa gaatgtgttt tattacctac tcaaccgacg ggcagacggt gttgcctcta      300

accagtgaca agaataggat aaaaaatggg ctagatcaac ttcagaaaat cgtgccggat      360

ggtcacacat tcatgcaggc cggctttagg aaagcaatac aacagattga gtctttcaac      420

agtggcaaca aggtcccatc catgattatc gcgatgactg atggagagtt agttgcacac      480

gcgttccagg atacattgag ggaggcgcag aaagcgagaa aactaggagc taacgtctac      540

actctaggcg tagccgatta taatctggat cagatcaccg ccatcgcgga ctcccccgga      600

cacgtattcg ctgtggagaa cgggttcaag gcccttcgtt caacgataga tgcactaact      660

agtaaagtgt gcttggatgt tacctccgta gagccctcta gcgaatgcgt gggagagccc      720

tatcatgtag tgattcatgg gaatgggttt caaaatttga aaaagaggga cgaggttata      780

tgcaggttta tttttaatga gagcactatt atagacgaga agcccacttc cattgataac      840

aatagcatga attgtccagg ccccaaactt gagaaacctg gagaggagta ttccatagaa      900

gtatctttga acaagggcaa gactttcttt aaatccaatg tctctatcac gagcacgact      960

tgcgggatat ttagaaac                                                    978


<210>  3138
<211>  261
<212>  DNA
<213>  Homo Sapiens

<400>  3138
tcagtcagag ttgaacaggt agttaagccc ccccaaaaca agacggaaag tgaaaatact       60

tcagataaac ccaaaagaaa gaaaaaggga ggcaaaaatg gaaaaaatag aagaaacaga      120

aagaagaaaa atccatgtaa tgcagaattt caaaatttct gcattcacgg agaatgcaaa      180

tatatagagc acctggaagc agtaacatgc aaatgtcagc aagaatattt cggtgaacgg      240

tgtggggaaa agtccatgaa a                                                261


<210>  3139
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  3139
actcacactg agatcaagag agtggcagag gaaaaggtca ctttgccctg ccaccatcaa       60

ctggggcttc cagaaaaaga cactctggat attgaatggc tgctcaccga taatgaaggg      120

aaccaaaaag tggtgatcac ttactccagt cgtcatgtct acaataactt gactgaggaa      180

cagaagggcc gagtggcctt tgcttccaat ttcctggcag gagatgcctc cttgcagatt      240

gaacctctga agcccagtga tgagggccgg tacacctgta aggttaagaa ttcagggcgc      300

tacgtgtgga gccatgtcat cttaaaagtc ttagtgagac catccaagcc caagtgtgag      360

ttggaaggag agctgacaga aggaagtgac ctgactttgc agtgtgagtc atcctctggc      420

acagagccca ttgtgtatta ctggcagcga atccgagaga aagagggaga ggatgaacgt      480

ctgcctccca aatctaggat tgactacaac caccctggac gagttctgct gcagaatctt      540

accatgtcct actctggact gtaccagtgc acagcaggca acgaagctgg gaaggaaagc      600

tgtgtggtgc gagtaactgt acagtatgta caaagcatcg gcatggttgc a               651


<210>  3140
<211>  690
<212>  DNA
<213>  Homo Sapiens

<400>  3140
caaaactccc agctgcagga ggagctgcgg ggcctgagag agacgttcag caacttcaca       60

gcgagcacgg aggcccaggt caagggcttg agcacccagg gaggcaatgt gggaagaaag      120

atgaagtcgc tagagtccca gctggagaaa cagcagaagg acctgagtga agatcactcc      180

agcctgctgc tccacgtgaa gcagttcgtg tctgacctgc ggagcctgag ctgtcagatg      240

gcggcgctcc agggcaatgg ctcagaaagg acctgctgcc cggtcaactg ggtggagcac      300

gagcgcagct gctactggtt ctctcgctcc gggaaggcct gggctgacgc cgacaactac      360

tgccggctgg aggacgcgca cctggtggtg gtcacgtcct gggaggagca gaaatttgtc      420

cagcaccaca taggccctgt gaacacctgg atgggcctcc acgaccaaaa cgggccctgg      480

aagtgggtgg acgggacgga ctacgagacg ggcttcaaga actggaggcc ggagcagccg      540

gacgactggt acggccacgg gctcggagga ggcgaggact gtgcccactt caccgacgac      600

ggccgctgga acgacgacgt ctgccagagg ccctaccgct gggtctgcga gacagagctg      660

gacaaggcca gccaggagcc acctctcctt                                       690


<210>  3141
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  3141
caaagtgcac agctgcaagc cgagctgcgg agcctgaagg aagctttcag caacttctcc       60

tcgagcaccc tgacggaggt ccaggcaatc agcacccacg gaggcagcgt gggtgacaag      120

atcacatccc taggagccaa gctggagaaa cagcagcagg acctgaaagc agatcacgat      180

gccctgctct tccatctgaa gcacttcccc gtggacctgc gcttcgtggc ctgccagatg      240

gagctcctcc acagcaacgg ctcccaaagg acctgctgcc ccgtcaactg ggtggagcac      300

caaggcagct gctactggtt ctctcactcc gggaaggcct gggctgaggc ggagaagtac      360

tgccagctgg agaacgcaca cctggtggtc atcaactcct gggaggagca gaaattcatt      420

gtacaacaca cgaacccctt caatacctgg ataggtctca cggacagtga tggctcttgg      480

aaatgggtgg atggcacaga ctataggcac aactacaaga actgggctgt cactcagcca      540

gataattggc acgggcacga gctgggtgga agtgaagact gtgttgaagt ccagccggat      600

ggccgctgga acgatgactt ctgcctgcag gtgtaccgct gggtgtgtga gaaaaggcgg      660

aatgccaccg gcgaggtggc c                                                681


<210>  3142
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  3142
gatatggaag acacagatga tgatgatgat gatgatgatg atgatgatga tgatgatgat       60

gatgatgagg aggacaactc tctttttcca acaagagagc caagaagcca tttttttcca      120

tttgatctgt ttccaatgtg tccatttgga tgtcagtgct attcacgagt tgtacattgc      180

tcagatttag gtttgacctc agtcccaacc aacattccat ttgatactcg aatgcttgat      240

cttcaaaaca ataaaattaa ggaaatcaaa gaaaatgatt ttaaaggact cacttcactt      300

tatggtctga tcctgaacaa caacaagcta acgaagattc acccaaaagc ctttctaacc      360

acaaagaagt tgcgaaggct gtatctgtcc cacaatcaac taagtgaaat accacttaat      420

cttcccaaat cattagcaga actcagaatt catgaaaata aagttaagaa aatacaaaag      480

gacacattca aaggaatgaa tgctttacac gttttggaaa tgagtgcaaa ccctcttgat      540

aataatggga tagagccagg ggcatttgaa ggggtgacgg tgttccatat cagaattgca      600

gaagcaaaac tgacctcagt tcctaaaggc ttaccaccaa ctttattgga gcttcactta      660

gattataata aaatttcaac agtggaactt gaggatttta aacgatacaa agaactacaa      720

aggctgggcc taggaaacaa caaaatcaca gatatcgaaa atgggagtct tgctaacata      780

ccacgtgtga gagaaataca tttggaaaac aataaactaa aaaaaatccc ttcaggatta      840

ccagagttga aatacctcca gataatcttc cttcattcta attcaattgc aagagtggga      900

gtaaatgact tctgtccaac agtgccaaag atgaagaaat ctttatacag tgcaataagt      960

ttattcaaca acccggtgaa atactgggaa atgcaacctg caacatttcg ttgtgttttg     1020

agcagaatga gtgttcagct tgggaacttt ggaatg                               1056


<210>  3143
<211>  2442
<212>  DNA
<213>  Homo Sapiens

<400>  3143
cacgtcaact gccctctcgt tgtcaagatc accctgcatg tccctgagca cctgattgct       60

gatgggagcc gcttcatctt gctggagggg agccagctgg atgccagtga ctggctgaac      120

cctgcccaag tggttctctt ctctcagcag aactccagcg gaccctgggc catggacctc      180

tgtgcccggc ggctcctgga cccctgtgaa caccaatgtg accccgaaac tggggaatgc      240

ctctgctatg aaggctacat gaaggatcca gtacataagc acctttgcat tcggaacgaa      300

tgggggacaa accaggggcc atggccttac acaatatttc agcgaggctt tgacctggtt      360

ttgggagagc agccctctga taaaatattt agattcacct acactcttgg ggagggcatg      420

tggttgcccc tcagcaagag ctttgtgatt ccaccagccg aactggccat caatccatca      480

gcaaagtgca agacggacat gactgtgatg gaggatgctg tggaggtcag agaggagctg      540

atgacttcat cctccttcga cagcctggag gttctcttag attcctttgg gccggtgcgc      600

gactgcagca aagataacgg gggctgcagt aagaatttcc gctgtatttc agatcgcaag      660

ctggactcca ctggttgcgt gtgcccatct ggactcagtc ccatgaagga cagctctggc      720

tgctatgacc gccacatcgg ggtggactgt tccgacggct tcaacggcgg ctgtgagcag      780

ctgtgcctcc agcagatggc gcccttcccg gacgacccca ccttgtataa catcctcatg      840

ttctgtgggt gcatcgagga ctacaagctt ggtgtggatg gacgctcttg ccaactcatc      900

acggagacct gtccagaggg aagtgactgt ggggaaagca gggagcttcc catgaaccag      960

accctctttg gggagatgtt ctttggttac aacaaccatt ccaaggaagt ggctgccgga     1020

caggtgctga aaggaacatt caggcaaaac aactttgctc gtggtttaga ccagcaactg     1080

ccagatggtc ttgtggtggc cactgtgccc ctggagaatc aatgcctaga ggagatctcg     1140

gagcccaccc ctgaccctga cttcctgact gggatggtga acttcagtga agtgtctggg     1200

taccctgtgc tgcagcactg gaaggtccgg tctgtgatgt accacatcaa actcaaccaa     1260

gtggccatct ctcaggccct cagcaatgct ctccactcgc tggatggggc tacatctcgt     1320

gcagattttg tggcgctgtt ggaccagttc ggcaaccatt acatccagga agctatctac     1380

ggctttgagg agtcctgttc tatctggtac ccaaacaagc aggtccagcg gcgactctgg     1440

ctggagtatg aagacatcag taaaggcaac tccccatcag atgagtctga ggagcgggaa     1500

agagacccca aggtgctgac attcccagaa tacatcacca gcttgtcaga ctccggcacc     1560

aagcgcatgg cggctggagt ccgcatggag tgccagagca agggacgatg cccctcgtcc     1620

tgccccctgt gtcatgtgac atccagccct gacacccctg ctgagccggt tctgctggag     1680

gtgaccaaag cagcccccat ctatgaacta gtgaccaaca accagaccca gaggctcttg     1740

caggaggcta ccatgagctc tctctggtgc tcagggactg gagatgtcat cgaggactgg     1800

tgtcgatgtg actccactgc ttttggagct gatggactcc ccacctgtgc gcctctccca     1860

cagcctgtgc tgagactctc cacggttcac gagcccagca gcactcttgt ggtcctggag     1920

tgggaacact cagagccacc aatcggggtg cagattgtag attacctcct ccgtcaagag     1980

aaagtcactg acaggatgga ccactccaaa gtggagacag aaacagtgct gagctttgtg     2040

gacgacatca tctctggagc aaagtctcct tgtgcaatgc catctcaggt gccggacaag     2100

cagctcacca ccatctctct gatcatacga tgcctggaac ctgacaccat ttacatgttc     2160

acgctgtggg gagtggacaa cacaggacgg cgctccaggc caagcgacgt gatcgtgaag     2220

accccatgcc ccgtggtgga tgatgtcaag gctcaagaaa tagcagacaa gatctacaat     2280

ctcttcaatg gctacactag tgggaaggag cagcagaccg cctacaacac cctcctggat     2340

ctgggttccc ccaccttaca ccgggtcctc taccactata accagcacta tgagagtttt     2400

ggggaattca cctggcgatg tgaggatgag ttaggtccca gg                        2442


<210>  3144
<211>  471
<212>  DNA
<213>  Homo Sapiens

<400>  3144
ggagctactg cggcagctag tagggaacca gactcacctt gtagacttaa gacagtaacg       60

gtctctactc taccggcttt gagggaaagt gacattggct ggtctggggc aagagccggt      120

gcaggtgccg gaaccggcgc aggagcggct gctgctgcgg cctcccctgg gagtccggga      180

agcgctggaa cagctgcgga gagtcgtcta ctattattcg tcaggaatga actgccggga      240

aggatcgccg ttcaggacga tctggataac actgagttac ctttttttac gttggaaatg      300

agcgggacag ccgccgacat atcattggtc cactggcgtc agcagtggct tgaaaacggt      360

acactttact ttcatgtatc tatgtcttca tcaggtcagc tggcacaggc aacggcacca      420

accttgcagg agccgtcaga gatagtagaa gagcagatgc acatattaca t               471


<210>  3145
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  3145
ctacccgaga tatgcaccca atgtccaggg agcgtgcaaa atttgtcaaa agtggccttt       60

tattgtaaaa cgacacgaga gctaatgctg catgcccgtt gctgcctgaa tcagaagggc      120

accatcttgg ggctggatct ccagaactgt tctctggagg accctggtcc aaactttcat      180

caggcacata ccactgtcat catagacctg caagcaaacc ccctcaaagg tgacttggcc      240

aacaccttcc gtggctttac tcagctccag actctgatac tgccacaaca tgtcaactgt      300

cctggaggaa ttaatgcctg gaatactatc acctcttata tagacaacca aatctgtcaa      360

gggcaaaaga acctttgcaa taacactggg gacccagaaa tgtgtcctga gaatggatct      420

tgtgtacctg atggtccagg tcttttgcag tgtgtttgtg ctgatggttt ccatggatac      480

aagtgtatgc gccagggctc gttctca                                          507


<210>  3146
<211>  3567
<212>  DNA
<213>  Homo Sapiens

<400>  3146
gccgcggcgg cggcggcggt gtcgggctca gccgcagccg aggccaagga atgtgaccgg       60

ccctgtgtca acggcggtcg ctgcaaccct ggcaccggcc agtgcgtctg ccccgccggc      120

tgggtgggcg agcaatgcca gcactgcggg ggccgcttca gactaactgg atcttctggg      180

tttgtgacag atggacctgg aaattataaa tacaaaacga agtgcacgtg gctcattgaa      240

ggacagccaa atagaataat gagacttcgt ttcaatcatt ttgctacaga gtgtagttgg      300

gaccatttat atgtttatga tggggactca atttatgcac cgctagttgc tgcatttagt      360

ggcctcattg ttcctgagag agatggcaat gagactgtcc ctgaggttgt tgccacatca      420

ggttatgcct tgctgcattt ttttagtgat gctgcttata atttgactgg atttaatatt      480

acttacagtt ttgatatgtg tccaaataac tgctcaggcc gaggagagtg taagatcagt      540

aatagcagcg atactgttga atgtgaatgt tctgaaaact ggaaaggtga agcatgtgac      600

attcctcact gtacagacaa ctgtggtttt cctcatcgag gcatctgcaa ttcaagtgat      660

gtcagaggat gctcctgctt ctcagactgg cagggtcctg gatgttcagt tcctgtacca      720

gctaaccagt cattttggac tcgagaggaa tattctaact taaagctccc cagagcatct      780

cataaagctg tggtcaatgg aaacattatg tgggttgttg gaggatatat gttcaaccac      840

tcagattata acatggttct agcgtatgac cttgcttcta gggagtggct tccactaaac      900

cgttctgtga acaatgtggt tgttagatat ggtcattctt tggcattata caaggataaa      960

atttacatgt atggaggaaa aattgattca actgggaatg tgaccaatga gttgagagtt     1020

tttcacattc ataatgagtc atgggtgttg ttgaccccta aggcaaagga gcagtatgca     1080

gtggttgggc actctgcaca cattgttaca ctgaagaatg gccgagtggt catgctggtc     1140

atctttggtc actgccctct ctatggatat ataagcaatg tgcaggaata tgatttggat     1200

aagaacacat ggagtatatt acacacccag ggtgcccttg tgcaaggggg ttacggccat     1260

agcagtgttt acgaccatag gaccagggcc ctatacgttc atggtggcta caaggctttc     1320

agtgccaata agtaccggct tgcagatgat ctctaccgat atgatgtgga tacccagatg     1380

tggaccattc ttaaggacag ccgatttttc cgttacttgc acacagctgt gatagtgagt     1440

ggaaccatgc tggtgtttgg aggaaacaca cacaatgaca catctatgag ccatggcgcc     1500

aaatgcttct cttcagattt catggcctat gacattgcct gtgaccgctg gtcagtgctt     1560

cccagacctg atctccacca tgatgtcaac agatttggcc attcagcagt cttacacaac     1620

agcaccatgt atgtgttcgg tggtttcaat agtctcctcc tcagcgacat cctggtattc     1680

acctcggaac agtgtgatgc gcatcggagt gaagccgctt gtttagcagc aggacctggt     1740

attcggtgtg tgtggaacac agggtcgtct cagtgtatct cgtgggcgct ggcaactgat     1800

gaacaagaag aaaagttaaa atcagaatgt ttttccaaaa gaactcttga ccatgacaga     1860

tgtgaccagc acacagattg ttacagctgc acagccaaca ccaatgactg ccactggtgc     1920

aatgaccatt gtgtccccag gaaccacagc tgctcagaag gccagatctc catttttagg     1980

tatgagaatt gccccaagga taaccccatg tactactgta acaagaagac cagctgcagg     2040

agctgtgccc tggaccagaa ctgccagtgg gagccccgga atcaggagtg cattgccctg     2100

cccgaaaata tctgtggcat tggctggcat ttggttggaa actcatgttt gaaaattact     2160

actgccaagg agaattatga caatgctaaa ttgttctgta ggaaccacaa tgcccttttg     2220

gcttctctta caacccagaa gaaggtagaa tttgtcctta agcagctgcg aataatgcag     2280

tcatctcaga gcatgtccaa gctcacctta accccatggg tcggccttcg gaagatcaat     2340

gtgtcctact ggtgctggga agatatgtcc ccatttacaa atagtttact acagtggatg     2400

ccgtctgagc ccagtgatgc tggattctgt ggaattttat cagaacccag tactcgggga     2460

ctgaaggctg caacctgcat caacccactc aatggtagtg tctgtgaaag gcctgcaaac     2520

cacagtgcta agcagtgccg gacaccatgt gccttgagga cagcatgtgg agattgcacc     2580

agcggcagct ctgagtgcat gtggtgcagc aacatgaagc agtgtgtgga ctccaatgcc     2640

tatgtggcct ccttcccttt tggccagtgt atggaatggt atacgatgag cacctgcccc     2700

cctgaaaatt gttcaggcta ctgtacctgt agtcattgct tggagcaacc aggctgtggc     2760

tggtgtactg atcccagcaa tactggcaaa gggaaatgca tagagggttc ctataaagga     2820

ccagtgaaga tgccttcgca agcccctaca ggaaatttct atccacagcc cctgctcaat     2880

tccagcatgt gtctagagga cagcagatac aactggtctt tcattcactg tccagcttgc     2940

caatgcaacg gccacagtaa atgcatcaat cagagcatct gtgagaagtg tgagaacctg     3000

accacaggca agcactgcga gacctgcata tctggcttct acggtgatcc caccaatgga     3060

gggaaatgtc agccatgcaa gtgcaatggg cacgcgtctc tgtgcaacac caacacgggc     3120

aagtgcttct gcaccaccaa gggcgtcaag ggggacgagt gccagctatg tgaggtagaa     3180

aatcgatacc aaggaaaccc tctcagagga acatgttatt atactcttct tattgactat     3240

cagttcacct ttagtctatc ccaggaagat gatcgctatt acacagctat caattttgtg     3300

gctactcctg acgaacaaaa cagggatttg gacatgttca tcaatgcctc caagaatttc     3360

aacctcaaca tcacctgggc tgccagtttc tcagctggaa cccaggctgg agaagagatg     3420

cctgttgttt caaaaaccaa cattaaggag tacaaagata gtttctctaa tgagaagttt     3480

gattttcgca accacccaaa tatcactttc tttgtttatg tcagtaattt cacctggccc     3540

atcaaaattc aggtgcaaac tgaacaa                                         3567


<210>  3147
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  3147
ctctacgcgc aggtgtccca gtccaagccg tgcgagagga ccggctcctg cttctcgggc       60

cgctgtgtca actccacctg cctctgcgac ccgggctggg tgggggacca gtgccagcac      120

tgccagggca ggttcaagtt aacagaacct tctggatatt taacagatgg cccaattaac      180

tataaatata aaactaaatg tacttggctc attgaaggct atccaaatgc agtgttaaga      240

ttaagattca atcattttgc tacagaatgt agctgggatc atatgtatgt ttatgatgga      300

gattcaatat atgcaccttt aatagctgta cttagtggtt tgatagtccc tgaaataagg      360

ggcaatgaaa ctgtgcctga agttgttact acatctggct atgcactgtt acattttttt      420

agtgatgctg cgtataatct aactggtttc aacattttct attcaatcaa ttcttgtcct      480

aacaattgct ctggtcatgg gaagtgtaca actagtgtct ctgttccaag tcaagtatat      540

tgtgaatgtg ataaatactg gaagggtgaa gcttgtgata ttccttactg taaagccaat      600

tgcggcagtc cagatcacgg ttactgtgac ctgactggag aaaaattatg tgtctgcaat      660

gatagttggc aaggtcctga ttgttctttg aatgttccct ctactgagtc ttactggatt      720

ctgccaaacg ttaaaccctt cagtccttct gtaggtcggg cttcacataa agcagtttta      780

cacgggaaat ttatgtgggt gattggtgga tatactttta actacagttc ttttcaaatg      840

gtcctaaatt acaatttaga aagcagtata tggaatgtag gaactccatc aaggggacct      900

ctccagagat atggacactc tcttgcttta tatcaggaaa acatctttat gtatggaggc      960

agaattgaaa caaatgatgg caatgtcaca gatgaattat gggtttttaa catacatagt     1020

cagtcatgga gtacaaaaac tcctactgtt cttggacatg gtcagcagta tgctgtggag     1080

ggacattcag cacatattat ggagttggat agtagagatg ttgtcatgat cataatattt     1140

ggatattctg caatatatgg ttatacaagc agcatacagg aataccatat ctgtgagtta     1200

cttaaaaatt gtaatttctt tattgattgg gaatgttttt ctctt                     1245


<210>  3148
<211>  1278
<212>  DNA
<213>  Homo Sapiens

<400>  3148
gcccccaggg gcacgcaggc tgaagaaagt cccttcgtgg gcaacccagg gaatatcaca       60

ggtgcccggg gactcacggg cacccttcgg tgtcagctcc aggttcaggg agagcccccc      120

gaggtacatt ggcttcggga tggacagatc ctggagctcg cggacagcac ccagacccag      180

gtgcccctgg gtgaggatga acaggatgac tggatagtgg tcagccagct cagaatcacc      240

tccctgcagc tttccgacac gggacagtac cagtgtttgg tgtttctggg acatcagacc      300

ttcgtgtccc agcctggcta tgttgggctg gagggcttgc cttacttcct ggaggagccc      360

gaagacagga ctgtggccgc caacaccccc ttcaacctga gctgccaagc tcagggaccc      420

ccagagcccg tggacctact ctggctccag gatgctgtcc ccctggccac ggctccaggt      480

cacggccccc agcgcagcct gcatgttcca gggctgaaca agacatcctc tttctcctgc      540

gaagcccata acgccaaggg ggtcaccaca tcccgcacag ccaccatcac agtgctcccc      600

cagcagcccc gtaacctcca cctggtctcc cgccaaccca cggagctgga ggtggcttgg      660

actccaggcc tgagcggcat ctaccccctg acccactgca ccctgcaggc tgtgctgtca      720

gacgatggga tgggcatcca ggcgggagaa ccagaccccc cagaggagcc cctcacctcg      780

caagcatccg tgccccccca tcagcttcgg ctaggcagcc tccatcctca caccccttat      840

cacatccgcg tggcatgcac cagcagccag ggcccctcat cctggaccca ctggcttcct      900

gtggagacgc cggagggagt gcccctgggc ccccctgaga acattagtgc tacgcggaat      960

gggagccagg ccttcgtgca ttggcaagag ccccgggcgc ccctgcaggg taccctgtta     1020

gggtaccggc tggcgtatca aggccaggac accccagagg tgctaatgga catagggcta     1080

aggcaagagg tgaccctgga gctgcagggg gacgggtctg tgtccaatct gacagtgtgt     1140

gtggcagcct acactgctgc tggggatgga ccctggagcc tcccagtacc cctggaggcc     1200

tggcgcccag ggcaagcaca gccagtccac cagctggtga aggaaccttc aactcctgcc     1260

ttctcgtggc cctggtgg                                                   1278


<210>  3149
<211>  834
<212>  DNA
<213>  Homo Sapiens

<400>  3149
caggagaacc aagatggtcg ttactctctg acctatatct acactgggct gtccaagcat       60

gttgaagacg tccccgcgtt tcaggccctt ggctcactca atgacctcca gttctttaga      120

tacaacagta aagacaggaa gtctcagccc atgggactct ggagacaggt ggaaggaatg      180

gaggattgga agcaggacag ccaacttcag aaggccaggg aggacatctt tatggagacc      240

ctgaaagaca ttgtggagta ttacaacgac agtaacgggt ctcacgtatt gcagggaagg      300

tttggttgtg agatcgagaa taacagaagc agcggagcat tctggaaata ttactatgat      360

ggaaaggact acattgaatt caacaaagaa atcccagcct gggtcccctt cgacccagca      420

gcccagataa ccaagcagaa gtgggaggca gaaccagtct acgtgcagcg ggccaaggct      480

tacctggagg aggagtgccc tgcgactctg cggaaatacc tgaaatacag caaaaatatc      540

ctggaccggc aagatcctcc ctctgtggtg gtcaccagcc accaggcccc aggagaaaag      600

aagaaactga agtgcctggc ctacgacttc tacccaggga aaattgatgt gcactggact      660

cgggccggcg aggtgcagga gcctgagtta cggggagatg ttcttcacaa tggaaatggc      720

acttaccagt cctgggtggt ggtggcagtg cccccgcagg acacagcccc ctactcctgc      780

cacgtgcagc acagcagcct ggcccagccc ctcgtggtgc cctgggaggc cagc            834


<210>  3150
<211>  297
<212>  DNA
<213>  Homo Sapiens

<400>  3150
atccagcgta ctccaaagat tcaggtttac tcacgtcatc cagcagagaa tggaaagtca       60

aatttcctga attgctatgt gtctgggttt catccatccg acattgaagt tgacttactg      120

aagaatggag agagaattga aaaagtggag cattcagact tgtctttcag caaggactgg      180

tctttctatc tcttgtacta cactgaattc acccccactg aaaaagatga gtatgcctgc      240

cgtgtgaacc atgtgacttt gtcacagccc aagatagtta agtgggatcg agacatg         297


<210>  3151
<211>  1548
<212>  DNA
<213>  Homo Sapiens

<400>  3151
gaggtgcgct tgtctgtacc cccgctggtg gaggtgatgc gaggaaagtc tgtcattctg       60

gactgcaccc ctacgggaac ccacgaccat tatatgctgg aatggttcct taccgaccgc      120

tcgggagctc gcccccgcct agcctcggct gagatgcagg gctctgagct ccaggtcaca      180

atgcacgaca cccggggccg cagtccccca taccagctgg actcccaggg gcgcctggtg      240

ctggctgagg cccaggtggg cgacgagcga gactacgtgt gcgtggtgag ggcaggggcg      300

gcaggcactg ctgaggccac tgcgcggctc aacgtgtttg caaagccaga ggccactgag      360

gtctccccca acaaagggac actgtctgtg atggaggact ctgcccagga gatcgccacc      420

tgcaacagcc ggaacgggaa cccggccccc aagatcacgt ggtatcgcaa cgggcagcgc      480

ctggaggtgc ccgtagagat gaacccagag ggctacatga ccagccgcac ggtccgggag      540

gcctcgggcc tgctctccct caccagcacc ctctacctgc ggctccgcaa ggatgaccga      600

gacgccagct tccactgcgc cgcccactac agcctgcccg agggccgcca cggccgcctg      660

gacagcccca ccttccacct caccctgcac tatcccacgg agcacgtgca gttctgggtg      720

ggcagcccgt ccaccccagc aggctgggta cgcgagggtg acactgtcca gctgctctgc      780

cggggggacg gcagccccag cccggagtat acgcttttcc gccttcagga tgagcaggag      840

gaagtgctga atgtgaatct cgaggggaac ttgaccctgg agggagtgac ccggggccag      900

agcgggacct atggctgcag agtggaggat tacgacgcgg cagatgacgt gcagctctcc      960

aagacgctgg agctgcgcgt ggcctatctg gaccccctgg agctcagcga ggggaaggtg     1020

ctttccttac ctctaaacag cagtgcagtc gtgaactgct ccgtgcacgg cctgcccacc     1080

cctgccctac gctggaccaa ggactccact cccctgggcg atggccccat gctgtcgctc     1140

agttctatca ccttcgattc caatggcacc tacgtatgtg aggcctccct gcccacagtc     1200

ccggtcctca gccgcaccca gaacttcacg ctgctggtcc aaggctcgcc agagctaaag     1260

acagcggaaa tagagcccaa ggcagatggc agctggaggg aaggagacga agtcacactc     1320

atctgctctg cccgcggcca tccagacccc aaactcagct ggagccaatt ggggggcagc     1380

cccgcagagc caatccccgg acggcagggt tgggtgagca gctctctgac cctgaaagtg     1440

accagcgccc tgagccgcga tggcatctcc tgtgaagcct ccaaccccca cgggaacaag     1500

cgccatgtct tccacttcgg caccgtgagc ccccagacct cccaggct                  1548


<210>  3152
<211>  2667
<212>  DNA
<213>  Homo Sapiens

<400>  3152
gatgttctgg aaggagacag ctcagaggac cgcgcttttc gcgtgcgcat cgcgggcgac       60

gcgccactgc agggcgtgct cggcggcgcc ctcaccatcc cttgccacgt ccactacctg      120

cggccaccgc cgagccgccg ggctgtgctg ggctctccgc gggtcaagtg gactttcctg      180

tcccggggcc gggaggcaga ggtgctggtg gcgcggggag tgcgcgtcaa ggtgaacgag      240

gcctaccggt tccgcgtggc actgcctgcg tacccagcgt cgctcaccga cgtctccctg      300

gcgctgagcg agctgcgccc caacgactca ggtatctatc gctgtgaggt ccagcacggc      360

atcgatgaca gcagcgacgc tgtggaggtc aaggtcaaag gggtcgtctt tctctaccga      420

gagggctctg cccgctatgc tttctccttt tctggggccc aggaggcctg tgcccgcatt      480

ggagcccaca tcgccacccc ggagcagctc tatgccgcct accttggggg ctatgagcaa      540

tgtgatgctg gctggctgtc ggatcagacc gtgaggtatc ccatccagac cccacgagag      600

gcctgttacg gagacatgga tggcttcccc ggggtccgga actatggtgt ggtggacccg      660

gatgacctct atgatgtgta ctgttatgct gaagacctaa atggagaact gttcctgggt      720

gaccctccag agaagctgac attggaggaa gcacgggcgt actgccagga gcggggtgca      780

gagattgcca ccacgggcca actgtatgca gcctgggatg gtggcctgga ccactgcagc      840

ccagggtggc tagctgatgg cagtgtgcgc taccccatcg tcacacccag ccagcgctgt      900

ggtgggggct tgcctggtgt caagactctc ttcctcttcc ccaaccagac tggcttcccc      960

aataagcaca gccgcttcaa cgtctactgc ttccgagact cggcccagcc ttctgccatc     1020

cctgaggcct ccaacccagc ctccaaccca gcctctgatg gactagaggc tatcgtcaca     1080

gtgacagaga ccctggagga actgcagctg cctcaggaag ccacagagag tgaatcccgt     1140

ggggccatct actccatccc catcatggag gacggaggag gtggaagctc cactccagaa     1200

gacccagcag aggcccctag gacgctccta gaatttgaaa cacaatccat ggtaccgccc     1260

acggggttct cagaagagga aggtaaggca ttggaggaag aagagaaata tgaagatgaa     1320

gaagagaaag aggaggaaga agaagaggag gaggtggagg atgaggctct gtgggcatgg     1380

cccagcgagc tcagcagccc gggccctgag gcctctctcc ccactgagcc agcagcccag     1440

gagaagtcac tctcccaggc gccagcaagg gcagtcctgc agcctggtgc atcaccactt     1500

cctgatggag agtcagaagc ttccaggcct ccaagggtcc atggaccacc tactgagact     1560

ctgcccactc ccagggagag gaacctagca tccccatcac cttccactct ggttgaggca     1620

agagaggtgg gggaggcaac tggtggtcct gagctatctg gggtccctcg aggagagagc     1680

gaggagacag gaagctccga gggtgcccct tccctgcttc cagccacacg ggcccctgag     1740

ggtaccaggg agctggaggc cccctctgaa gataattctg gaagaactgc cccagcaggg     1800

acctcagtgc aggcccagcc agtgctgccc actgacagcg ccagccgagg tggagtggcc     1860

gtggtccccg catcaggtga ctgtgtcccc agcccctgcc acaatggtgg gacatgcttg     1920

gaggaggagg aaggggtccg ctgcctatgt ctgcctggct atggggggga cctgtgcgat     1980

gttggcctcc gcttctgcaa ccccggctgg gacgccttcc agggcgcctg ctacaagcac     2040

ttttccacac gaaggagctg ggaggaggca gagacccagt gccggatgta cggcgcgcat     2100

ctggccagca tcagcacacc cgaggaacag gacttcatca acaaccggta ccgggagtac     2160

cagtggatcg gactcaacga caggaccatc gaaggcgact tcttgtggtc ggatggcgtc     2220

cccctgctct atgagaactg gaaccctggg cagcctgaca gctacttcct gtctggagag     2280

aactgcgtgg tcatggtgtg gcatgatcag ggacaatgga gtgacgtgcc ctgcaactac     2340

cacctgtcct acacctgcaa gatggggctg gtgtcctgtg ggccgccacc ggagctgccc     2400

ctggctcaag tgttcggccg cccacggctg cgctatgagg tggacactgt gcttcgctac     2460

cggtgccggg aaggactggc ccagcgcaat ctgccgctga tccgatgcca agagaacggt     2520

cgttgggagg ccccccagat ctcctgtgtg cccagaagac ctgcccgagc tctgcaccca     2580

gaggaggacc cagaaggacg tcaggggagg ctactgggac gctggaaggc gctgttgatc     2640

cccccttcca gccccatgcc aggtccc                                         2667


<210>  3153
<211>  993
<212>  DNA
<213>  Homo Sapiens

<400>  3153
gatgaggaag cttcgggcgc tgacacctca ggcgtcctgg acccggactc tgtcacaccc       60

acctacagcg ccatgtgtcc tttcggctgc cactgccacc tgcgggtggt tcagtgctcc      120

gacctgggtc tgaagtctgt gcccaaagag atctcccctg acaccacgct gctggacctg      180

cagaacaacg acatctccga gctccgcaag gatgacttca agggtctcca gcacctctac      240

gccctcgtcc tggtgaacaa caagatctcc aagatccatg agaaggcctt cagcccactg      300

cggaagctgc agaagctcta catctccaag aaccacctgg tggagatccc gcccaaccta      360

cccagctccc tggtggagct ccgcatccac gacaaccgca tccgcaaggt gcccaaggga      420

gtgttcagcg ggctccggaa catgaactgc atcgagatgg gcgggaaccc actggagaac      480

agtggctttg aacctggagc cttcgatggc ctgaagctca actacctgcg catctcagag      540

gccaagctga ctggcatccc caaagacctc cctgagaccc tgaatgaact ccacctagac      600

cacaacaaaa tccaggccat cgaactggag gacctgcttc gctactccaa gctgtacagg      660

ctgggcctag gccacaacca gatcaggatg atcgagaacg ggagcctgag cttcctgccc      720

accctccggg agctccactt ggacaacaac aagttggcca gggtgccctc agggctccca      780

gacctcaagc tcctccaggt ggtctatctg cactccaaca acatcaccaa agtgggtgtc      840

aacgacttct gtcccatggg cttcggggtg aagcgggcct actacaacgg catcagcctc      900

ttcaacaacc ccgtgcccta ctgggaggtg cagccggcca ctttccgctg cgtcactgac      960

cgcctggcca tccagtttgg caactacaaa aag                                   993


<210>  3154
<211>  2598
<212>  DNA
<213>  Homo Sapiens

<400>  3154
gcggcgacgt cccgaccaga gcgtgtgtgg cccgatgggg tcatcccctt tgtcattggg       60

ggaaacttca ctggtagcca gagggcagtc ttccggcagg ccatgaggca ctgggagaag      120

cacacctgtg tcaccttcct ggagcgcact gacgaggaca gctatattgt gttcacctat      180

cgaccttgcg ggtgctgctc ctacgtgggt cgccgcggcg ggggccccca ggccatctcc      240

atcggcaaga actgtgacaa gttcggcatt gtggtccacg agctgggcca cgtcgtcggc      300

ttctggcacg aacacactcg gccagaccgg gaccgccacg tttccatcgt tcgtgagaac      360

atccagccag ggcaggagta taacttcctg aagatggagc ctcaggaggt ggagtccctg      420

ggggagacct atgacttcga cagcatcatg cattacgctc ggaacacatt ctccaggggc      480

atcttcctgg ataccattgt ccccaagtat gaggtgaacg gggtgaaacc tcccattggc      540

caaaggacac ggctcagcaa gggggacatt gcccaagccc gcaagcttta caagtgccca      600

gcctgtggag agaccctgca agacagcaca ggcaacttct cctcccctga ataccccaat      660

ggctactctg ctcacatgca ctgcgtgtgg cgcatctctg tcacacccgg ggagaagatc      720

atcctgaact tcacgtccct ggacctgtac cgcagccgcc tgtgctggta cgactatgtg      780

gaggtccgag atggcttctg gaggaaggcg cccctccgag gccgcttctg cgggtccaaa      840

ctccctgagc ctatcgtctc cactgacagc cgcctctggg ttgaattccg cagcagcagc      900

aattgggttg gaaagggctt ctttgcagtc tacgaagcca tctgcggggg tgatgtgaaa      960

aaggactatg gccacattca atcgcccaac tacccagacg attaccggcc cagcaaagtc     1020

tgcatctggc ggatccaggt gtctgagggc ttccacgtgg gcctcacatt ccagtccttt     1080

gagattgagc gccacgacag ctgtgcctac gactatctgg aggtgcgcga cgggcacagt     1140

gagagcagca ccctcatcgg gcgctactgt ggctatgaga agcctgatga catcaagagc     1200

acgtccagcc gcctctggct caagttcgtc tctgacgggt ccattaacaa agcgggcttt     1260

gccgtcaact ttttcaaaga ggtggacgag tgctctcggc ccaaccgcgg gggctgtgag     1320

cagcggtgcc tcaacaccct gggcagctac aagtgcagct gtgaccccgg gtacgagctg     1380

gccccagaca agcgccgctg tgaggctgct tgtggcggat tcctcaccaa gctcaacggc     1440

tccatcacca gcccgggctg gcccaaggag taccccccca acaagaactg catctggcag     1500

ctggtggccc ccacccagta ccgcatctcc ctgcagtttg acttctttga gacagagggc     1560

aatgatgtgt gcaagtacga cttcgtggag gtgcgcagtg gactcacagc tgactccaag     1620

ctgcatggca agttctgtgg ttctgagaag cccgaggtca tcacctccca gtacaacaac     1680

atgcgcgtgg agttcaagtc cgacaacacc gtgtccaaaa agggcttcaa ggcccacttc     1740

ttctcagaca aggacgagtg ctccaaggat aacggcggct gccagcagga ctgcatcaac     1800

acgttcggca gttatgagtg ccaatgccgc agtggcttcg tcctccatga caacaagcac     1860

gactgcaaag aagccggctg tgaccacaag gtgacatcca ccagtggtac catcaccagc     1920

cccaactggc ctgacaagta tcccagcaag aatgagtgca cgtgggccat ctccagcacc     1980

cccgggcacc gggtcaagct gaccttcatg gagatggaca tcgagtccca gcctgagtgt     2040

gcctacgacc acctagaggt gttcgacggg cgagacgcca aggcccccgt cctcggccgc     2100

ttctgtggga gcaagaagcc cgagcccgtc ctggccacag gcagccgcat gttcctgcgc     2160

ttctactcag ataactcggt ccagcgaaag ggcttccagg cctcccacgc cacagagtgc     2220

gggggccagg tacgggcaga cgtgaagacc aaggaccttt actcccacgc ccagtttggc     2280

gacaacaact accctggggg tgtggactgt gagtgggtca ttgtggccga ggaaggctac     2340

ggcgtggagc tcgtgttcca gacctttgag gtggaggagg agaccgactg cggctatgac     2400

tacatggagc tcttcgacgg ctacgacagc acagccccca ggctggggcg ctactgtggc     2460

tcagggcctc ctgaggaggt gtactcggcg ggagattctg tcctggtgaa gttccactcg     2520

gatgacacca tcaccaaaaa aggtttccac ctgcgataca ccagcaccaa gttccaggac     2580

acactccaca gcaggaag                                                   2598


<210>  3155
<211>  324
<212>  DNA
<213>  Homo Sapiens

<400>  3155
aacgccaaag gaaactactg taagaggacc ccgctctaca tcgacttcaa ggagattggg       60

tgggactcct ggatcatcgc tccgcctgga tacgaagcct atgaatgccg tggtgtttgt      120

aactaccccc tggcagagca tctcacaccc acaaagcatg caattatcca ggccttggtc      180

cacctcaaga attcccagaa agcttccaaa gcctgctgtg tgcccacgaa gctagagccc      240

atctccatcc tctatttaga caaaggcgtc gtcacctaca agtttaaata cgaaggcatg      300

gccgtctccg aatgtggctg taga                                             324


<210>  3156
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  3156
caagcagatg gtatctcagc tgaggttact gcctcttcct caaaacatag cgggcctgaa       60

aataaccagt gttccctcca ccctttccaa atcagcttcc gccagctggg ttgggatcac      120

tggatcattg ctcccccttt ctacacccca aactactgta aaggaacttg tctccgagta      180

ctacgcgatg gtctcaattc ccccaatcac gccattattc agaaccttat caatcagttg      240

gtggaccaga gtgtcccccg gccctcctgt gtcccgtata agtatgttcc aattagtgtc      300

cttatgattg aggcaaatgg gagtattttg tacaaggagt atgagggtat gattgctgag      360

tcttgtacat gcaga                                                       375


<210>  3157
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  3157
caagccaaac acaaacagcg gaaacgcctt aagtccagct gtaagagaca ccctttgtac       60

gtggacttca gtgacgtggg gtggaatgac tggattgtgg ctcccccggg gtatcacgcc      120

ttttactgcc acggagaatg cccttttcct ctggctgatc atctgaactc cactaatcat      180

gccattgttc agacgttggt caactctgtt aactctaaga ttcctaaggc atgctgtgtc      240

ccgacagaac tcagtgctat ctcgatgctg taccttgacg agaatgaaaa ggttgtatta      300

aagaactatc aggacatggt tgtggagggt tgtgggtgtc gc                         342


<210>  3158
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  3158
cagtggattg aacctcggaa ttgcgccagg agatacctca aggtagactt tgcagatatt       60

ggctggagtg aatggattat ctcccccaag tcctttgatg cctattattg ctctggagca      120

tgccagttcc ccatgccaaa gtctttgaag ccatcaaatc atgctaccat ccagagtata      180

gtgagagctg tgggggtcgt tcctgggatt cctgagcctt gctgtgtacc agaaaagatg      240

tcctcactca gtattttatt ctttgatgaa aataagaatg tagtgcttaa agtataccct      300

aacatgacag tagagtcttg cgcttgcaga                                       330


<210>  3159
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  3159
agccctaagc atcactcaca gcgggccagg aagaagaata agaactgccg gcgccactcg       60

ctctatgtgg acttcagcga tgtgggctgg aatgactgga ttgtggcccc accaggctac      120

caggccttct actgccatgg ggactgcccc tttccactgg ctgaccacct caactcaacc      180

aaccatgcca ttgtgcagac cctggtcaat tctgtcaatt ccagtatccc caaagcctgt      240

tgtgtgccca ctgaactgag tgccatctcc atgctgtacc tggatgagta tgataaggtg      300

gtactgaaaa attatcagga gatggtagta gagggatgtg ggtgccgc                   348


<210>  3160
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  3160
gcagccaaca aacgaaaaaa tcaaaaccgc aataaatcca gctctcatca ggactcctcc       60

agaatgtcca gtgttggaga ttataacaca agtgagcaaa aacaagcctg taagaagcac      120

gaactctatg tgagcttccg ggatctggga tggcaggact ggattatagc accagaagga      180

tacgctgcat tttattgtga tggagaatgt tcttttccac ttaacgccca tatgaatgcc      240

accaaccacg ctatagttca gactctggtt catctgatgt ttcctgacca cgtaccaaag      300

ccttgttgtg ctccaaccaa attaaatgcc atctctgttc tgtactttga tgacagctcc      360

aatgtcattt tgaaaaaata tagaaatatg gtagtacgct catgtggctg ccac            414


<210>  3161
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  3161
tccacgggga gcaaacagcg cagccagaac cgctccaaga cgcccaagaa ccaggaagcc       60

ctgcggatgg ccaacgtggc agagaacagc agcagcgacc agaggcaggc ctgtaagaag      120

cacgagctgt atgtcagctt ccgagacctg ggctggcagg actggatcat cgcgcctgaa      180

ggctacgccg cctactactg tgagggggag tgtgccttcc ctctgaactc ctacatgaac      240

gccaccaacc acgccatcgt gcagacgctg gtccacttca tcaacccgga aacggtgccc      300

aagccctgct gtgcgcccac gcagctcaat gccatctccg tcctctactt cgatgacagc      360

tccaacgtca tcctgaagaa atacagaaac atggtggtcc gggcctgtgg ctgccac         417


<210>  3162
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  3162
gcggtgaggc cgctaagacg tcgtcaaccc aagaagagta atgaactacc gcaggcaaat       60

agattaccag gtattttcga cgacgttagg ggttctcacg gacgtcaagt gtgcagaaga      120

cacgagctat atgtatcatt tcaggacctt ggttggttgg attgggtaat cgctccgcag      180

ggatatagtg cgtactattg tgaaggtgaa tgctcattcc cacttgatag ctgcatgaac      240

gcaactaacc atgcaatttt gcagtcttta gtccacctta tgaagcctaa tgccgtacca      300

aaagcgtgct gcgctccgac taagctatct gcgacgtccg ttctatatta tgattcctca      360

aataacgtta tccttcgtaa gcacagaaat atggtcgtta aagcctgcgg ctgtcat         417


<210>  3163
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  3163
gcagtgaggc cactgaggag gaggcagccg aagaaaagca acgagctgcc gcaggccaac       60

cgactcccag ggatctttga tgacgtccgc ggctcccacg gccggcaggt ctgccgtcgg      120

cacgagctct acgtcagctt ccaggacctc ggctggctgg taattgctga ctctccttgt      180

ttc                                                                    183


<210>  3164
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  3164
cagaatctgg atagtatgct tcatggcact gggatgaaat cagactccga ccagaaaaag       60

tcagaaaatg gagtaacctt agcaccagag gataccttgc cttttttaaa gtgctattgc      120

tcagggcact gtccagatga tgctattaat aacacatgca taactaatgg acattgcttt      180

gccatcatag aagaagatga ccagggagaa accacattag cttcagggtg tatgaaatat      240

gaaggatctg attttcagtg caaagattct ccaaaagccc agctacgccg gacaatagaa      300

tgttgtcgga ccaatttatg taaccagtat ttgcaaccca cactgccccc tgttgtcata      360

ggtccgtttt ttgatggcag cattcga                                          387


<210>  3165
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  3165
aagaaagagg atggtgagag tacagccccc accccccgtc caaaggtctt gcgttgtaaa       60

tgccaccacc attgtccaga agactcagtc aacaatattt gcagcacaga cggatattgt      120

ttcacgatga tagaagagga tgactctggg ttgcctgtgg tcacttctgg ttgcctagga      180

ctagaaggct cagattttca gtgtcgggac actcccattc ctcatcaaag aagatcaatt      240

gaatgctgca cagaaaggaa cgaatgtaat aaagacctac accctacact gcctccattg      300

aaaaacagag attttgttga tggacctata caccacagg                             339


<210>  3166
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  3166
tcgcagaatc aagaacggct atgtgcgttt aaagatccgt atcagcaaga ccttgggata       60

ggtgagagta gaatctctca tgaaaatggg acaatattat gctcgaaagg tagcacctgc      120

tatggccttt gggagaaatc aaaaggggac ataaatcttg taaaacaagg atgttggtct      180

cacattggag atccccaaga gtgtcactat gaagaatgtg tagtaactac cactcctccc      240

tcaattcaga atggaacata ccgtttctgc tgttgtagca cagatttatg taatgtcaac      300

tttactgaga attttccacc tcctgacaca acaccactca gtccacctca ttcatttaac      360

cgagatgaga ca                                                          372


<210>  3167
<211>  2475
<212>  DNA
<213>  Homo Sapiens

<400>  3167
gacttgaacg aggtccctca ggtcaccgtc cagcctgcgt ccaccgtcca gaagcccgga       60

ggcactgtga tcttgggctg cgtggtggaa cctccaagga tgaatgtaac ctggcgcctg      120

aatggaaagg agctgaatgg ctcggatgat gctctgggtg tcctcatcac ccacgggacc      180

ctcgtcatca ctgcccttaa caaccacact gtgggacggt accagtgtgt ggcccggatg      240

cctgcggggg ctgtggccag cgtgccagcc actgtgacac tagccaatct ccaggacttc      300

aagttagatg tgcagcacgt gattgaagtg gatgagggaa acacagcagt cattgcctgc      360

cacctgcctg agagccaccc caaagcccag gtccggtaca gcgtcaaaca agagtggctg      420

gaggcctcca gaggtaacta cctgatcatg ccctcaggga acctccagat tgtgaatgcc      480

agccaggagg acgagggcat gtacaagtgt gcagcctaca acccagtgac ccaggaagtg      540

aaaacctccg gctccagcga caggctacgt gtgcgccgct ccaccgctga ggctgcccgc      600

atcatctacc ccccagaggc ccaaaccatc atcgtcacca aaggccagag tctcattctg      660

gagtgtgtgg ccagtggaat cccaccccca cgggtcacct gggccaagga tgggtccagt      720

gtcaccggct acaacaagac gcgcttcctg ctgagcaacc tcctcatcga caccaccagc      780

gaggaggact caggcaccta ccgctgcatg gccgacaatg gggttgggca gcccggggca      840

gcggtcatcc tctacaatgt ccaggtgttt gaaccccctg aggtcaccat ggagctatcc      900

cagctggtca tcccctgggg ccagagtgcc aagcttacct gtgaggtgcg tgggaacccc      960

ccgccctccg tgctgtggct gaggaatgct gtgcccctca tctccagcca gcgcctccgg     1020

ctctcccgca gggccctgcg cgtgctcagc atggggcctg aggacgaagg cgtctaccag     1080

tgcatggccg agaacgaggt tgggagcgcc catgccgtag tccagctgcg gacctccagg     1140

ccaagcataa ccccaaggct atggcaggat gctgagctgg ctactggcac acctcctgta     1200

tcaccctcca aacttggcaa ccctgagcag atgctgaggg ggcaaccggc gctccccaga     1260

cccccaacgt cagtggggcc tgcttcccca cagtgtccag gagagaaggg gcagggggct     1320

cccgccgagg ctcccatcat cctcagctcg ccccgcacct ccaagacaga ctcatatgaa     1380

ctggtgtggc ggcctcggca tgagggcagt ggccgggcgc caatcctcta ctatgtggtg     1440

aaacaccgca aggtcacaaa ttcctctgac gattggacca tctctggcat tccagccaac     1500

cagcaccgcc tgaccctcac cagacttgac cccgggagct tgtatgaagt ggagatggca     1560

gcttacaact gtgcgggaga gggccagaca gccatggtca ccttccgaac tggacggcgg     1620

cccaaacccg agatcatggc cagcaaggag cagcagatcc agagagacga ccctggagcc     1680

agtccccaga gcagcagcca gccagaccac ggccgcctct cccccccaga agctcccgac     1740

aggcccacca tctccacggc ctccgagacc tcagtgtacg tgacctggat tccccgtggg     1800

aatggtgggt tcccaatcca gtccttccgt gtggagtaca agaagctaaa gaaagtggga     1860

gactggattc tggccaccag cgccatcccc ccatcacggc tgtccgtgga gatcacgggc     1920

ctagagaaag gcacctccta caagtttcga gtccgggctc tgaacatgct gggggagagc     1980

gagcccagcg ccccctctcg gccctacgtg gtgtcgggct acagcggtcg cgtgtacgag     2040

aggcccgtgg caggtcctta tatcaccttc acggatgcgg tcaatgagac caccatcatg     2100

ctcaagtgga tgtacatccc agcaagtaac aacaacaccc caatccatgg cttttatatc     2160

tattatcgac ccacagacag tgacaatgat agtgactaca agaaggatat ggtggaaggg     2220

gacaagtact ggcactccat cagccacctg cagccagaga cctcctacga cattaagatg     2280

cagtgcttca atgaaggagg ggagagcgag ttcagcaacg tgatgatctg tgagaccaaa     2340

gctcggaagt cttctggcca gcctggtcga ctgccacccc caactctggc cccaccacag     2400

ccgccccttc ctgaaaccat agagcggccg gtgggcactg gggccatggt ggctcgctcc     2460

agcgacctgc cctat                                                      2475


<210>  3168
<211>  558
<212>  DNA
<213>  Homo Sapiens

<400>  3168
gctgccggca cagtcttcac taccgtagaa gaccttggct ccaagatact cctcacctgc       60

tccttgaatg acagcgccac agaggtcaca gggcaccgct ggctgaaggg gggcgtggtg      120

ctgaaggagg atgcgctgcc cggccagaaa acggagttca aggtggactc ggacgaccag      180

tggggagagt actcctgcgt cttcctcccc gagcccatgg gcacggccaa catccagctc      240

cacgggcctc ccagagtgaa ggctgtgaag tcgtcagaac acatcaacga gggggagacg      300

gccatgctgg tctgcaagtc agagtccgtg ccacctgtca ctgactgggc ctggtacaag      360

atcactgact ctgaggacaa ggccctcatg aacggctccg agagcaggtt cttcgtgagt      420

tcctcgcagg gccggtcaga gctacacatt gagaacctga acatggaggc cgaccccggc      480

cagtaccggt gcaacggcac cagctccaag ggctccgacc aggccatcat cacgctccgc      540

gtgcgcagcc acctggcc                                                    558


<210>  3169
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  3169
tgtatttttc ccgtgattct gaatgagtta tcatcaacag ttgaaacgat cacgcatttc       60

ccggaagtaa cggacgggga atgcgtgttc ccctttcact ataaaaatgg tacgtactat      120

gattgcatca agagcaaggc aaggcacaaa tggtgttcct taaacaaaac ctatgagggg      180

tattggaaat tttgcagcgc cgaagacttt gcgaactgtg ttttcccatt ttggtacaga      240

aggcttattt attgggaatg caccgacgac ggagaggctt tcggtaaaaa atggtgctct      300

ttgacaaaaa atttcaataa agatcgtatt tggaagtact gcgaa                      345


<210>  3170
<211>  240
<212>  DNA
<213>  Homo Sapiens

<400>  3170
gatgggaatt ccaccagaag tcctgaaact aatggcctcc tctgtggaga ccctgaggaa       60

aactgtgcag ctaccaccac acaatcaaag cggaaaggcc acttctctag gtgccccaag      120

caatacaagc attactgcat caaagggaga tgccgcttcg tggtggccga gcagacgccc      180

tcctgtgtct gtgatgaagg ctacattgga gcaaggtgtg agagagttga cttgttttac      240


<210>  3171
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  3171
aaagaatcat gtgatgtaca gctttatata aagagacaat ctgaacactc catcttagca       60

ggagatccct ttgaactaga atgccctgtg aaatactgtg ctaacaggcc tcatgtgact      120

tggtgcaagc tcaatggaac aacatgtgta aaacttgaag atagacaaac aagttggaag      180

gaagagaaga acatttcatt tttcattcta cattttgaac cagtgcttcc taatgacaat      240

gggtcatacc gctgttctgc aaattttcag tctaatctca ttgaaagcca ctcaacaact      300

ctttatgtga ca                                                          312


<210>  3172
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  3172
gctccctttg acgtgattgg acccccggag cccatcctgg ccgttgtggg tgaggacgcc       60

gagctgccct gtcgcctgtc tccgaacgcg agcgccgagc acttggagct acgctggttc      120

cgaaagaagg tttcgccggc cgtgctggtg catagggacg ggcgcgagca ggaagccgag      180

cagatgcccg agtaccgcgg gcgggcgacg ctggtccagg acggcatcgc caaggggcgc      240

gtggccttga ggatccgtgg cgtcagagtc tctgacgacg gggagtacac gtgctttttc      300

agggaggatg gaagctacga agaagccctg gtgcatctga aggtggctgc tctgggctct      360

gaccctcaca tcagtatgca agttcaagag aatggagaaa tctgtctgga gtgcacctca      420

gtgggatggt acccagagcc ccaggtgcag tggagaactt ccaagggaga gaagtttcca      480

tctacatcag agtccaggaa tcctgatgaa gaaggtttgt tcactgtggc tgcttcagtg      540

atcatcagag acacttctgc gaaaaatgtg tcctgctaca tccagaatct ccttcttggc      600

caggagaaga aagtagaaat atccatacca gcttcctccc tcccaagg                   648


<210>  3173
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  3173
cagtttattg tcgtggggcc cactgatccc atcttggcca cggttggaga aaacactacg       60

ttacgctgcc atctgtcacc cgagaaaaat gctgaggaca tggaggtgcg gtggttccgg      120

tctcagttct cccccgcagt gtttgtgtat aaaggtggca gagagagaac agaggagcag      180

atggaggagt accgaggaag aaccaccttt gtgagcaaag acatcagcag gggcagcgtg      240

gccctggtca tacacaacat cacagcccag gaaaacggca cctaccgctg ttacttccaa      300

gaaggcaggt cctacgatga ggccatcctg cacctcgtag tggcaggact aggctctaag      360

cccctcattt caatgagggg ccatgaagac gggggcatcc ggctggagtg catatctaga      420

gggtggtacc caaagcccct cacagtgtgg agggacccct acggtggggt tgcgcctgcc      480

ctgaaagagg tctccatgcc tgatgcagac ggcctcttca tggtcaccac ggctgtgatc      540

atcagagaca agtctgtgag gaacatgtcc tgctctatca acaacaccct gctcggccag      600

aagaaagaaa gtgtcatttt tattccagaa tcctttatgc ccagtgtgtc tccctgtgca      660


<210>  3174
<211>  699
<212>  DNA
<213>  Homo Sapiens

<400>  3174
cagtttactg tcgtggggcc agctaatccc atcctggcca tggtgggaga aaacactaca       60

ttacgctgcc atctgtcacc cgagaaaaat gctgaggaca tggaggtgcg gtggttccgg      120

tctcagttct cccccgcagt gtttgtgtat aagggtggga gagagagaac agaggagcag      180

atggaggagt accggggaag aatcaccttt gtgagcaaag acatcaacag gggcagcgtg      240

gccctggtca tacataacgt cacagcccag gagaatggga tctaccgctg ttacttccaa      300

gaaggcaggt cctacgatga ggccatccta cgcctcgtgg tggcaggcct tgggtctaag      360

cccctcattg aaatcaaggc ccaagaggat gggagcatct ggctggagtg catatctgga      420

gggtggtacc cagagcccct cacagtgtgg agggacccct acggtgaggt tgtgcccgcc      480

ctgaaggagg tttccatcgc tgatgctgac ggcctcttca tggtcaccac agctgtgatc      540

atcagagaca agtatgtgag gaatgtgtcc tgctctgtca acaacaccct gctcggccag      600

gagaaggaaa ctgtcatttt tattccagaa tcctttatgc ccagcgcatc tccctggatg      660

gtggccctag ctgtcatcct gaccgcatct ccctggatg                             699


<210>  3175
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  3175
caggtcactg tcgtggggcc cactgatccc atcctggcca tggtgggaga aaacactacg       60

ttacgatgct gtctgtcacc cgaggaaaat gctgaggaca tggaggtgcg gtggttccag      120

tctcagttct cccctgcagt gtttgtgtat aagggtggaa gagagagaac agaggagcag      180

aaggaggagt accgagggag aaccaccttt gtgagcaaag acagcagggg cagcgtggcc      240

ctgatcatac acaatgttac agccgaggat aacggcatct accagtgtta cttccaagaa      300

ggcaggtcct gcaatgaggc catcctgcac cttgtg                                336


<210>  3176
<211>  675
<212>  DNA
<213>  Homo Sapiens

<400>  3176
cagttttctg tgcttggacc ctctgggccc atcctggcca tggtgggtga agacgctgat       60

ctgccctgtc acctgttccc gaccatgagt gcagagacca tggagctgaa gtgggtgagt      120

tccagcctaa ggcaggtggt gaacgtgtat gcagatggaa aggaagtgga agacaggcag      180

agtgcaccgt atcgagggag aacttcgatt ctgcgggatg gcatcactgc agggaaggct      240

gctctccgaa tacacaacgt cacagcctct gacagtggaa agtacttgtg ttatttccaa      300

gatggtgact tctatgaaaa agccctggtg gagctgaagg ttgcagcact gggttctgat      360

cttcacgttg atgtgaaggg ttacaaggat ggagggatcc atctggagtg caggtccact      420

ggctggtacc cccaacccca aatacagtgg agcaacaaca agggagagaa catcccgact      480

gtggaagcac ctgtggttgc agacggagtg ggcctgtatg cagtagcagc atctgtgatc      540

atgagaggca gctctgggga gggtgtatcc tgtaccatca gaagttccct cctcggcctg      600

gaaaagacag ccagcatttc catcgcagac cccttcttca ggagcgccca gaggtggatc      660

gccgccctgg caggg                                                       675


<210>  3177
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3177
cagttttctg tgcttggacc ctctgggccc atcctggcca tggtgggtga agacgctgat       60

ctgccctgtc acctgttccc gaccatgagt gcagagacca tggagctgaa gtgggtaagt      120

tccagcctaa ggcaggtggt gaacgtgtat gcagatggaa aggaagtgga agacaggcag      180

agtgcaccgt atcgagggag aacttcgatt ctgcgggatg gcatcactgc agggaaggct      240

gctctccgaa tacacaacgt cacagcctct gacagtggaa agtacttgtg ttatttccaa      300

gatggtgact tctatgaaaa agccctggtg gagctgaagg ttgcagcact gggttctaat      360

cttcacgtcg aagtgaaggg ttatgaggat ggagggatcc atctggagtg caggtccacc      420

ggctggtacc cccaacccca aatacagtgg agcaacgcca agggagagaa catcccagct      480

gtggaagcac ctgtggttgc agatggagtg ggcctatatg aagtagcagc atctgtgatc      540

atgagaggcg gctccgggga gggtgtatcc tgcatcatca gaaattccct cctcggcctg      600

gaaaagacag ccagcatttc catcgcagac cccttcttca ggagcgccca gccctgg         657


<210>  3178
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3178
cagttttctg tgcttggacc ctctgggccc atcctggcca tggtgggtga agacgctgat       60

ctgccctgtc acctgttccc gaccatgagt gcagagacca tggagctgag gtgggtgagt      120

tccagcctaa ggcaggtggt gaacgtgtat gcagatggaa aggaagtgga agacaggcag      180

agtgcaccgt atcgagggag aacttcgatt ctgcgggatg gcatcactgc agggaaggct      240

gctctccgaa tacacaacgt cacagcctct gacagtggaa agtacttgtg ttatttccaa      300

gatggtgact tctacgaaaa agccctggtg gagctgaagg ttgcagcatt gggttctgat      360

cttcacattg aagtgaaggg ttatgaggat ggagggatcc atctggagtg caggtccact      420

ggctggtacc cccaacccca aataaagtgg agcgacacca agggagagaa catcccggct      480

gtggaagcac ctgtggttgc agatggagtg ggcctgtatg cagtagcagc atctgtgatc      540

atgagaggca gctctggtgg gggtgtatcc tgcatcatca gaaattccct cctcggcctg      600

gaaaagacag ccagcatatc catcgcagac cccttcttca ggagcgccca gccctgg         657


<210>  3179
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  3179
agtatttgga aggcggattt tgacgtgacg ggaccccatg cacctatctt agcgatggca       60

ggcgggcatg tagagcttca atgccaatta tttcctaaca taagcgcaga ggatatggag      120

ctaaggtggt acaggtgtca gccaagtcta gccgtccaca tgcacgagcg tggaatggat      180

atggatggcg aacagaagtg gcaatacaga ggtcgtacca ctttcatgtc cgatcatgtc      240

gccagaggga aggccatggt acgtagtcat agagtcacaa cttttgataa cagaacttac      300

tgttgcaggt tcaaagacgg ggtaaagttt ggagaagcta ccgtccaggt ccaagtagct      360

ggtttgggaa gggagccgag gattcaagta accgatcaac aggacggggt aagagctgaa      420

tgcacgagcg cagggtgctt tccgaagtca tgggtagaaa gaagggattt tagagggcag      480

gctaggcctg ctgtgacgaa tcttagtgca tctgctacga ccagattatg ggctgtcgcg      540

agttccctaa cgctgtggga cagagctgta gaaggattat cctgctcaat aagttccccg      600

cttttacctg aaagacgtaa ggtagccgaa tctcatcttc cagcgacctt tagtaggagc      660

agccagttca ctgcttggaa ggca                                             684


<210>  3180
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  3180
ccagagaaac tccagactga gctggcttct ttaaaagtga atggaccttc ccagcccatc       60

ctcgtcagag tgggagaaga tatacagcta acctgttacc tgtcccccaa ggcgaatgca      120

cagagcatgg aggtgaggtg ggaccgatcc caccgttacc ctgctgtgca tgtgtatatg      180

gatggggacc atgtggctgg agagcagatg gcagagtaca gagggaggac tgtgctggtg      240

agtgacgcca ttgacgaggg cagactgacc ctgcagatac tcagtgccag accttcggac      300

gacgggcagt accgctgcct ttttgaaaaa gatgatgtct accaagaggc cagtttggat      360

ctgaaggtgg taggtctggg ttcttcccca ctgatcactg tggaggggca agaagatgga      420

gaaatgcagc cgatgtgctc ttcagatggg tggttcccac agccccacgt gccatggagg      480

gacatggaag gaaagacgat accatcatct tcccaggccc tgactcaagg cagccacggg      540

ctgttccacg tgcagacatt gctaagggtc acaaacatct ccgctgtgga cgtcacttgt      600

tccatcagca tccccttttt gggcgaggag aaaatcgcaa ctttttctct ctcaggttgg      660


<210>  3181
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  3181
cagtggcaag tcactggacc gggcaagttt gtccaggcct tggtggggga ggacgccgtg       60

ttctcctgct ccctctttcc tgagaccagt gcagaggcta tggaagtgcg gttcttcagg      120

aatcagttcc atgctgtggt ccacctctac agagatgggg aagactggga atctaagcag      180

atgccacagt atcgagggag aactgagttt gtgaaggact ccattgcagg ggggcgtgtc      240

tctctaaggc taaaaaacat cactccctcg gacatcggcc tgtatgggtg ctggttcagt      300

tcccagattt acgatgagga ggccacctgg gagctgcggg tggcagcact gggctcactt      360

cctctcattt ccatcgtggg atatgttgac ggaggtatcc agttactctg cctgtcctca      420

ggctggttcc cccagcccac agccaagtgg aaaggtccac aaggacagga tttgtcttca      480

gactccagag caaatgcaga tgggtacagc ctgtatgatg tggagatctc cattatagtc      540

caggaaaatg ctgggagcat attgtgttcc atccaccttg ctgagcagag tcatgaggtg      600

gaatccaagg tattgatagg agagacgttt ttccagccct caccttggcg cctggcttct      660


<210>  3182
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  3182
gcactgggct cagttcctct catttccatc gcgggatatg ttgatagaga catccagcta       60

ctctgtcagt cctcgggctg gttcccccgg cccacagcga agtggaaagg tccacaagga      120

caggatttgt ccacagactc caggacaaac agagacatgc atggcctgtt tgatgtggag      180

atctctctga ccgtccaaga gaacgccggg agcatatcct gttccatgcg gcatgctcat      240

ctgagccgag aggtggaatc cagggtacag ataggagata cctttttcaa gcctatatca      300

tggcacctgg ctaccaaa                                                    318


<210>  3183
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  3183
agctcagagg tcaaggtgct aggccctgag tatcccatcc tggccctcgt cggggaggag       60

gtggagttcc cgtgccacct atggccacag ctggatgccc agcaaatgga gatccgctgg      120

ttccggagtc agaccttcaa tgtggtacac ctgtaccagg agcagcagga gctccctggc      180

aggcagatgc cggcgttccg gaacaggacc aagttggtca aggacgacat cgcctatggc      240

agcgtggtcc tgcagcttca cagcatcatc ccctctgaca agggcacata tggctgccgc      300

ttccactccg acaacttctc tggcgaagct ctctgggaac tggaggtagc agggctgggc      360

tcagaccctc acctctccct tgagggcttc aaggaaggag gcattcagct gaggctcaga      420

tccagtggct ggtaccccaa gcctaaggtt cagtggagag accaccaggg acagtgcctg      480

cctccagagt ttgaagccat cgtctgggat gcccaggacc tgttcagtct ggaaacatct      540

gtggttgtcc gagcgggagc cctcagcaat gtgtccgtct ccatccagaa tctcctcttg      600

agccagaaga aagagttggt ggtccagata gcagacgtgt tcgtacccgg agcctctgcg      660

tggaag                                                                 666


<210>  3184
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3184
attaacatca ccagctcagc ttcccaggaa ggaacgcgac taaacttaat ctgtactgta       60

tggcataaga aagaagaggc tgaggggttt gtagtgtttt tgtgcaagga caggtctgga      120

gactgttctc ctgagaccag tttaaaacag ctgagactta aaagggatcc tgggatagat      180

ggtgttggtg aaatatcatc tcagttgatg ttcaccataa gccaagtcac accgttgcac      240

agtgggacct accagtgttg tgccagaagc cagaagtcag gtatccgcct tcagggccat      300

tttttctcca ttctattcac agagacaggg aactacacag tgacgggatt gaaacaaaga      360

caacaccttg agttcagcca taatgaaggc actctcagt                             399


<210>  3185
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  3185
ttcaaggtcg ccacgccgta ttccctgtat gtctgtcccg aggggcagaa cgtcaccctc       60

acctgcaggc tcttgggccc tgtggacaaa gggcacgatg tgaccttcta caagacgtgg      120

taccgcagct cgaggggcga ggtgcagacc tgctcagagc gccggcccat ccgcaacctc      180

acgttccagg accttcacct gcaccatgga ggccaccagg ctgccaacac cagccacgac      240

ctggctcagc gccacgggct ggagtcggcc tccgaccacc atggcaactt ctccatcacc      300

atgcgcaacc tgaccctgct ggatagcggc ctctactgct gcctggtggt ggagatcagg      360

caccaccact cggagcacag ggtccatggt gccatggagc tgcaggtgca gacaggcaaa      420

gatgcaccat ccaactgtgt ggtgtaccca tcctcctccc aggagagtga aaacatcacg      480

gctgca                                                                 486


<210>  3186
<211>  975
<212>  DNA
<213>  Homo Sapiens

<400>  3186
gcgctgctga ggaggcagac gtccggtccc ttgtaccttg ctgtgtggga caaggctgac       60

gactcagggg gaagaatgac tacagcctgc agtcctcata atcctcagtg cacagctgac      120

ttgggtgctc agtacatcac ctgcactcct cattatgcca aaaaacacca acgtttttat      180

gatgaactgt tagcctatgg cgttttgagg cctctaagct cgcctattga aggaatggtg      240

atgaaagaag gagactgtaa ctttgtggca cctcaaggaa tttcttcaat tattaagcat      300

tacttgaaag aatcaggtgc agaagtctac ttcagacatc gtgtgacaca gatcaaccta      360

agagatgaca aatgggaagt atccaaacaa acaggctccc ctgagcagtt tgatcttatt      420

gttctcacaa tgccagttcc tgagattctg cagcttcaag gtgacatcac caccttaatt      480

agtgaatgcc aaaggcagca actggaggct gtgagctact cctctcgata tgctctgggc      540

ctcttttatg aagctggtac gaagattgat gtcccttggg ctgggcagta catcaccagt      600

aatccctgca tacgcttcgt ctccattgat aataagaagc gcaatataga gtcatcagaa      660

attgggcctt ccctcgtgat tcacaccact gtcccatttg gagttacata cttggaacac      720

agcattgagg atgtgcaaga gttagtcttc cagcagctgg aaaacatttt gccgggtttg      780

cctcagccaa ttgctaccaa atgccaaaaa tggagacatt cacaggttac aaatgctgct      840

gccaactgtc ctggccaaat gactctgcat cacaaacctt tccttgcatg tggaggggat      900

ggatttactc agtccaactt tgatggctgc atcacttctg ccctatgtgt tctggaagct      960

ttaaagaatt atatt                                                       975


<210>  3187
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  3187
cgtgaagaag agatcacccc cgtggtttcc atagcatata aagtattaga ggtctttcct       60

aagggcagat gggttctgat cacctgttgt gcccctcagc ctccaccccc aataacgtac      120

agtctgtgtg gaactaaaaa tattaaagtg gcgaaaaaag tggtaaaaac gcacgagccg      180

gcctctttca atcttaatgt gacgcttaaa tcttctcccg accttcttac atacttttgc      240

tgggcctcct caacaagtgg ggcccacgtt gactccgcgc gtctgcagat gcattgggag      300

ttatggtcaa aacccgtatc cgagttgcgt gccaatttta cgttacagga cagaggggct      360

ggacctagag tagaaatgat ttgccaggct tcctctggtt cccccccaat aacaaacagt      420

ttaattggaa aggacggcca agttcatctg cagcagaggc cctgtcacag gcagccggct      480

aatttctctt tcctaccttc acagacatca gactggttct ggtgccaagc ggccaataac      540

gcaaatgtcc agcatagtgc cctaactgta gtaccccctg gaggagacca gaaaatggaa      600

gattggcagg gtcctcttga atcacccatt ttggcgcttc cactttatag atcaacccgt      660

cgtctgagtg aggaggagtt cggtgggttt aggataggaa acggagaagt aagaggaagg      720

aaagcagccg ctatg                                                       735


<210>  3188
<211>  426
<212>  DNA
<213>  Homo Sapiens

<400>  3188
gtgtccgagc ccacgacggt ggcgtttgac gtgcggcccg gcggcgtcgt gcattccttc       60

tcccataacg tgggcccggg ggacaaatat acgtgtatgt tcacttacgc ctctcaagga      120

gggaccaatg agcaatggca gatgagtctg gggaccagcg aagaccacca gcacttcacc      180

tgcaccatct ggaggcccca ggggaagtcc tatctgtact tcacacagtt caaggcagag      240

gtgcggggcg ctgagattga gtacgccatg gcctactcta aagccgcatt tgaaagggaa      300

agtgatgtcc ctctgaaaac tgaggaattt gaagtgacca aaacagcagt ggctcacagg      360

cccggggcat tcaaagctga gctgtccaag ctggtgattg tggccaaggc atcgcgcact      420

gagctg                                                                 426


<210>  3189
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  3189
gccgcaccca ctccgccagg atgggaaccc acaccagacg cgccatggtg cccctataag       60

gtcttgccag aaggccctga agcgggggga ggccgtctgt gctttaggag cccagctagg      120

ggattccgtt gtcaggcccc tggatgtgtt ctgcacgcgc ccgccggcag atcactaagg      180

gcgagtgtac ttcgtaatag aagcgtcctt cttcagtggc gtttagcgcc agctgcggcg      240

cgtcgtgtac gtgcattcgc tttgaattgc tcatggcgtg gcgcatacac gagatttcct      300

tgtgaacgtg tcttattagg tgcgtcatgc agagattatc tacttccaga tgtgcatgat      360

tcagttcttt ataggttgtg cttgcaacct cttccactga gggccggacc ggctgcagct      420

gcccctgaga cacccgaacc tgcagagtgt gtagaattca ctgctgaacc cgccggtatg      480

caagat                                                                 486


<210>  3190
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3190
cttcaggtca cagtgcccga caagaagaag gtggccatgc tcttccagcc cactgtgctt       60

cgctgccact tctcaacatc ctcccatcag cctgcagttg tgcagtggaa gttcaagtcc      120

tactgccagg atcgcatggg agaatccttg ggcatgtcct ctacccgggc ccaatctctc      180

agcaagagaa acctggaatg ggacccctac ttggattgtt tggacagcag gaggactgtt      240

cgagtagtag cttcaaaaca gggctcgact gtcaccctgg gagatttcta caggggcaga      300

gagatcacga ttgttcatga tgcagatctt caaattggaa agcttatgtg gggagacagc      360

ggactctatt actgtattat caccacccca gatgacctgg aggggaaaaa tgaggactca      420

gtggaactgc tggtgttggg caggacaggg ctgcttgctg atctcttgcc cagttttgct      480

gtggagatta tgccagag                                                    498


<210>  3191
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  3191
ggcccggaag gccactatga gatgctgggc acctgccgca tggtgtgcga cccctacccc       60

gcgcggggcc ccggcgccgg cgcgcggacc gacggcggcg acgccctgag cgagcagagc      120

ggcgcgcccc cgccttccac gctggtgcag ggcccccagg ggaagccggg ccgcaccggc      180

aagcccggcc ctccggggcc tcccggggac ccaggtcctc ccggccctgt ggggccgccg      240

ggggagaagg gtgagccagg caagccgggc cctccggggc tgccgggcgc ggggggcagc      300

ggcgccatca gcactgccac ctacaccacg gtgccgcgcg tggccttcta cgccggcctc      360

aagaaccccc acgagggtta cgaggtactc aagtttgacg acgtggtcac caacctaggc      420

aacaactacg acgcggccag cggcaagttt acgtgcaaca ttcccggcac ctactttttc      480

acctaccatg tcctcatgcg cggcggcgac ggcaccagta tgtgggcaga cctctgcaag      540

aatggccagg tgcgggccag tgctattgcc caggacgcgg accagaacta cgactacgcc      600

agcaacagcg tgatcctgca cctggacgcc ggcgacgagg tcttcatcaa gctggatgga      660

ggcaaagcac acggcggcaa cagcaacaaa tacagcacgt tctctggctt catcatctac      720

tccgac                                                                 726


<210>  3192
<211>  798
<212>  DNA
<213>  Homo Sapiens

<400>  3192
cattatgaga tgatgggaac atgtagaatg atttgcgacc catacactgc cgctcccggc       60

ggggaaccac cgggagctaa agcgcaacct cctgggccgt ccacagcggc tctggaggta      120

atgcaggacc ttagtgcaaa cccacccccg ccctttatcc aaggacctaa gggggaccca      180

ggtaggccag gcaagcctgg gcctcgtggt ccaccgggag agccggggcc tcctggtcca      240

agaggtccac ctggcgaaaa gggggattct ggtagaccag gccttccagg gttgcaacta      300

accgccggaa ccgccagcgg cgttggtgta gttggaggcg gcgctggggt cgggggtgat      360

tcagagggag aggttacgag tgccttaagc gctactttta gtggacctaa gatagccttc      420

tacgtgggcc taaagtcccc ccacgagggg tacgaggttc tgaaattcga tgatgtcgta      480

actaatctgg gaaatcacta tgacccaacc acgggcaaat tttcctgtca agtgcgtggc      540

atatatttct ttacttatca tatactaatg agaggaggtg acggcacctc tatgtgggct      600

gatctatgca agaacggtca ggtgagggcc tccgccatag cgcaagatgc tgatcaaaat      660

tacgactatg caagtaactc cgttgtactg catctggaca gtggtgacga ggtttatgtg      720

aaattagacg ggggaaaagc gcatggcggc aataacaata agtatagtac tttttcagga      780

ttccttttat atccagac                                                    798


<210>  3193
<211>  1671
<212>  DNA
<213>  Homo Sapiens

<400>  3193
gctgacacgg aggcggtggt ctgcgtgggg accgcctgct acacggccca ctcgggcaag       60

ctgagcgctg ccgaggccca gaaccactgc aaccagaacg ggggcaacct ggccactgtg      120

aagagcaagg aggaggccca gcacgtccag cgagtactgg cccagctcct gaggcgggag      180

gcagccctga cggcgaggat gagcaagttc tggattgggc tccagcgaga gaagggcaag      240

tgcctggacc ctagtctgcc gctgaagggc ttcagctggg tgggcggggg ggaggacacg      300

ccttactcta actggcacaa ggagctccgg aactcgtgca tctccaagcg ctgtgtgtct      360

ctgctgctgg acctgtccca gccgctcctt cccagccgcc tccccaagtg gtctgagggc      420

ccctgtggga gcccaggctc ccccggaagt aacattgagg gcttcgtgtg caagttcagc      480

ttcaaaggca tgtgccggcc tctggccctg gggggcccag gtcaggtgac ctacaccacc      540

cccttccaga ccaccagttc ctccttggag gctgtgccct ttgcctctgc ggccaatgta      600

gcctgtgggg aaggtgacaa ggacgagact cagagtcatt atttcctgtg caaggagaag      660

gcccccgatg tgttcgactg gggcagctcg ggccccctct gtgtcagccc caagtatggc      720

tgcaacttca acaatggggg ctgccaccag gactgctttg aaggggggga tggctccttc      780

ctctgcggct gccgaccagg attccggctg ctggatgacc tggtgacctg tgcctctcga      840

aacccttgca gctccagccc atgtcgtggg ggggccacgt gcgtcctggg accccatggg      900

aaaaactaca cgtgccgctg cccccaaggg taccagctgg actcgagtca gctggactgt      960

gtggacgtgg atgaatgcca ggactccccc tgtgcccagg agtgtgtcaa cacccctggg     1020

ggcttccgct gcgaatgctg ggttggctat gagccgggcg gtcctggaga gggggcctgt     1080

caggatgtgg atgagtgtgc tctgggtcgc tcgccttgcg cccagggctg caccaacaca     1140

gatggctcat ttcactgctc ctgtgaggag ggctacgtcc tggccgggga ggacgggact     1200

cagtgccagg acgtggatga gtgtgtgggc ccggggggcc ccctctgcga cagcttgtgc     1260

ttcaacacac aagggtcctt ccactgtggc tgcctgccag gctgggtgct ggccccaaat     1320

ggggtctctt gcaccatggg gcctgtgtct ctgggaccac catctgggcc ccccgatgag     1380

gaggacaaag gagagaaaga agggagcacc gtgccccgtg ctgcaacagc cagtcccaca     1440

aggggccccg agggcacccc caaggctaca cccaccacaa gtagaccttc gctgtcatct     1500

gacgccccca tcacatctgc cccactcaag atgctggccc ccagtgggtc cccaggcgtc     1560

tggagggagc ccagcatcca tcacgccaca gctgcctctg gcccccagga gcctgcaggt     1620

ggggactcct ccgtggccac acaaaacaac gatggcactg acgggcaaaa g              1671


<210>  3194
<211>  810
<212>  DNA
<213>  Homo Sapiens

<400>  3194
gacccactgc ttggcgcctt tgctcgcagg gacttccgga aaggctcccc tcaactggtc       60

tgcagcctgc ctggccccca gggcccaccc ggccccccag gagccccagg gccctcagga      120

atgatgggac gaatgggctt tcctggcaaa gacggccaag atggacacga cggcgaccgg      180

ggggacagcg gagaggaagg tccacctggc cggacaggta accggggaaa gccaggacca      240

aagggcaaag ccggggccat tgggcgggct ggcccccgtg gccccaaggg ggtcaacggt      300

acccccggga agcatggcac accaggcaag aaggggccca agggcaagaa gggggagcca      360

ggcctcccag gcccctgcag ctgtggcagt ggccatacca agtcagcttt ctcggtggca      420

gtgaccaaga gctacccacg ggagcggctg cccatcaagt ttgacaagat tctgatgaac      480

gagggtggcc actacaatgc ttccagcggc aagttcgtct gcggcgtgcc tgggatctac      540

tacttcacct acgacatcac gctggccaac aagcacctgg ccatcggcct ggtgcacaac      600

ggccagtacc gcatccggac ctttgatgcc aacaccggca accacgatgt ggcctcaggc      660

tccaccatcc tggctctcaa gcagggtgac gaagtttggc tgcagatctt ctactcagag      720

cagaacgggc tcttctatga cccttactgg acagacagcc tctttacggg cttcctaatc      780

tatgccgacc aggatgaccc caacgaggta                                       810


<210>  3195
<211>  939
<212>  DNA
<213>  Homo Sapiens

<400>  3195
ctgggcccga cccccggccc gggatcctct gagctgcgct cggccttctc ggcggcacgc       60

accacccccc tggagggcac gtcggagatg gcggtgacct tcgacaaggt gtacgtgaac      120

atcgggggcg acttcgatgt ggccaccggc cagtttcgct gccgcgtgcc cggcgcctac      180

ttcttctcct tcacggctgg caaggccccg cacaagagcc tgtcggtgat gctggtgcga      240

aaccgcgacg aggtgcaggc gctggccttc gacgagcagc ggcggccagg cgcgcggcgc      300

gcagccagcc agagcgccat gctgcagctc gactacggcg acacagtgtg gctgcggctg      360

catggcgccc cgcagtacgc gctaggcgcg cccggcgcca ccttcagcgg ctacctagtc      420

tacgccgacg ccgacgctga cgcgcctgcg cgcgggccgc ccgcgccccc cgagccgcgc      480

tcggccttct cggcggcgcg cacgcgcagc ttggtgggct cggacgctgg ccccgggccg      540

cggcaccaac cactcgcctt cgacaccgag ttcgtcaaca ttggcggcga cttcgacgcg      600

gcggccggcg tgttccgctg ccgtctgccc ggcgcctact tcttctcctt cacgctgggc      660

aagctgccgc gtaagacgct gtcggttaag ctgatgaaga accgcgacga ggtgcaggcc      720

atgatttacg acgacggcgc gtcgcggcgc cgcgagatgc agagccagag cgtgatgctg      780

gccctgcggc gcggcgacgc cgtctggctg ctcagccacg accacgacgg ctacggcgcc      840

tacagcaacc acggcaagta catcaccttc tccggcttcc tggtgtaccc cgacctcgcc      900

cccgccgccc cgccgggcct cggggcctcg gagctactg                             939


<210>  3196
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  3196
tcgcccccac tggacgacaa caagatcccc agcctctgcc cggggcaccc cggccttcca       60

ggcacgccgg gccaccatgg cagccggggc ttgccgggcc gcgatggccg cgacggccgc      120

gacggcgcgc ccggggctcc gggagagaaa ggcgagggcg ggaggccggg actgccggga      180

cctcgagggg accccgggcc gcgaggagag gcgggacccg cggggcccac cgggcctgcc      240

ggggagtgct cggtgcctcc gcgatccgcc ttcagcgcca agcgctccga gagccgggtg      300

cctccgccgt ctgacgcacc cttgcccttc gaccgcgtgc tggtgaacga gcagggacat      360

tacgacgccg tcaccggcaa gttcacctgc caggtgcctg gggtctacta cttcgccgtc      420

catgccaccg tctaccgggc cagcctgcag tttgatctgg tgaagaatgg cgaatccatt      480

gcctctttct tccagttttt cggggggtgg cccaagccag cctcgctctc ggggggggcc      540

atggtgaggc tggagcctga ggaccaagtg tgggtgcagg tgggtgtggg tgactacatt      600

ggcatctatg ccagcatcaa gacagacagc accttctccg gatttctggt gtactccgac      660

tggcacagct ccccagtctt tgct                                             684


<210>  3197
<211>  2064
<212>  DNA
<213>  Homo Sapiens

<400>  3197
tccattccca tccctcagaa gttatttggg gaggtgactt cccctctgtt ccccaagcct       60

taccccaaca actttgaaac aaccactgtg atcacagtcc ccacgggata cagggtgaag      120

ctcgtcttcc agcagtttga cctggagcct tctgaaggct gcttctatga ttatgtcaag      180

atctctgctg ataagaaaag cctggggagg ttctgtgggc aactgggttc tccactgggc      240

aaccccccgg gaaagaagga atttatgtcc caagggaaca agatgctgct gaccttccac      300

acagacttct ccaacgagga gaatgggacc atcatgttct acaagggctt cctggcctac      360

taccaagctg tggaccttga tgaatgtgct tcccggagca aattagggga ggaggatccc      420

cagccccagt gccagcacct gtgtcacaac tacgttggag gctacttctg ttcctgccgt      480

ccaggctatg agcttcagga agacaggcat tcctgccagg ctgagtgcag cagcgagctg      540

tacacggagg catcaggcta catctccagc ctggagtacc ctcggtccta cccccctgac      600

ctgcgctgca actacagcat ccgggtggag cggggcctca ccctgcacct caagttcctg      660

gagccttttg atattgatga ccaccagcaa gtacactgcc cctatgacca gctacagatc      720

tatgccaacg ggaagaacat tggcgagttc tgtgggaagc aaaggccccc cgacctcgac      780

accagcagca atgctgtgga tctgctgttc ttcacagatg agtcggggga cagccggggc      840

tggaagctgc gctacaccac cgagatcatc aagtgccccc agcccaagac cctagacgag      900

ttcaccatca tccagaacct gcagcctcag taccagttcc gtgactactt cattgctacc      960

tgcaagcaag gctaccagct catagagggg aaccaggtgc tgcattcctt cacagctgtc     1020

tgccaggatg atggcacgtg gcatcgtgcc atgcccagat gcaagatcaa ggactgtggg     1080

cagccccgaa acctgcctaa tggtgacttc cgttacacca ccacaatggg agtgaacacc     1140

tacaaggccc gtatccagta ctactgccat gagccatatt acaagatgca gaccagagct     1200

ggcagcaggg agtctgagca aggggtgtac acctgcacag cacagggcat ttggaagaat     1260

gaacagaagg gagagaagat tcctcggtgc ttgccagtgt gtgggaagcc cgtgaacccc     1320

gtggaacaga ggcagcgcat catcggaggg caaaaagcca agatgggcaa cttcccctgg     1380

caggtgttca ccaacatcca cgggcgcggg ggcggggccc tgctgggcga ccgctggatc     1440

ctcacagctg cccacaccct gtatcccaag gaacacgaag cgcaaagcaa cgcctctttg     1500

gatgtgttcc tgggccacac aaatgtggaa gagctcatga agctaggaaa tcaccccatc     1560

cgcagggtca gcgtccaccc ggactaccgt caggatgagt cctacaattt tgagggggac     1620

atcgccctgc tggagctgga aaatagtgtc accctgggtc ccaacctcct ccccatctgc     1680

ctccctgaca acgatacctt ctacgacctg ggcttgatgg gctatgtcag tggcttcggg     1740

gtcatggagg agaagattgc tcatgacctc aggtttgtcc gtctgcccgt agctaatcca     1800

caggcctgtg agaactggct ccggggaaag aataggatgg atgtgttctc tcaaaacatg     1860

ttctgtgctg gacacccatc tctaaagcag gacgcctgcc agggggatag tgggggcgtt     1920

tttgcagtaa gggacccgaa cactgatcgc tgggtggcca cgggcatcgt gtcctggggc     1980

atcgggtgca gcaggggcta tggcttctac accaaagtgc tcaactacgt ggactggatc     2040

aagaaagaga tggaggagga ggac                                            2064


<210>  3198
<211>  2019
<212>  DNA
<213>  Homo Sapiens

<400>  3198
gagcctacca tgtatgggga gatcctgtcc cctaactatc ctcaggcata tcccagtgag       60

gtagagaaat cttgggacat agaagttcct gaagggtatg ggattcacct ctacttcacc      120

catctggaca ttgagctgtc agagaactgt gcgtatgact cagtgcagat aatctcagga      180

gacactgaag aagggaggct ctgtggacag aggagcagta acaatcccca ctctccaatt      240

gtggaagagt tccaagtccc atacaacaaa ctccaggtga tctttaagtc agacttttcc      300

aatgaagagc gttttacggg gtttgctgca tactatgttg ccacagacat aaatgaatgc      360

acagattttg tagatgtccc ttgtagccac ttctgcaaca atttcattgg tggttacttc      420

tgctcctgcc ccccggaata tttcctccat gatgacatga agaattgcgg agttaattgc      480

agtggggatg tattcactgc actgattggg gagattgcaa gtcccaatta tcccaaacca      540

tatccagaga actcaaggtg tgaataccag atccggttgg agaaagggtt ccaagtggtg      600

gtgaccttgc ggagagaaga ttttgatgtg gaagcagctg actcagcggg aaactgcctt      660

gacagtttag tttttgttgc aggagatcgg caatttggtc cttactgtgg tcatggattc      720

cctgggcctc taaatattga aaccaagagt aatgctcttg atatcatctt ccaaactgat      780

ctaacagggc aaaaaaaggg ctggaaactt cgctatcatg gagatccaat gccctgccct      840

aaggaagaca ctcccaattc tgtttgggag cctgcgaagg caaaatatgt ctttagagat      900

gtggtgcaga taacctgtct ggatgggttt gaagttgtgg agggacgtgt tggtgcaaca      960

tctttctatt cgacttgtca aagcaatgga aagtggagta attccaaact gaaatgtcaa     1020

cctgtggact gtggcattcc tgaatccatt gagaatggta aagttgaaga cccagagagc     1080

actttgtttg gttctgtcat ccgctacact tgtgaggagc catattacta catggaaaat     1140

ggaggaggtg gggagtatca ctgtgctggt aacgggagct gggtgaatga ggtgctgggc     1200

ccggagctgc cgaaatgtgt tccagtctgt ggagtcccca gagaaccctt tgaagaaaaa     1260

cagaggataa ttggaggatc cgatgcagat attaaaaact tcccctggca agtcttcttt     1320

gacaacccat gggctggtgg agcgctcatt aatgagtact gggtgctgac ggctgctcat     1380

gttgtggagg gaaacaggga gccaacaatg tatgttgggt ccacctcagt gcagacctca     1440

cggctggcaa aatccaagat gctcactcct gagcatgtgt ttattcatcc gggatggaag     1500

ctgctggaag tcccagaagg acgaaccaat tttgataatg acattgcact ggtgcggctg     1560

aaagacccag tgaaaatggg acccaccgtc tctcccatct gcctaccagg cacctcttcc     1620

gactacaacc tcatggatgg ggacctggga ctgatctcag gctggggccg aacagagaag     1680

agagatcgtg ctgttcgcct caaggcggca aggttacctg tagctccttt aagaaaatgc     1740

aaagaagtga aagtggagaa acccacagca gatgcagagg cctatgtttt cactcctaac     1800

atgatctgtg ctggaggaga gaagggcatg gatagctgta aaggggacag tggtggggcc     1860

tttgctgtac aggatcccaa tgacaagacc aaattctacg cagctggcct ggtgtcctgg     1920

gggccccagt gtgggaccta tgggctctac acacgggtaa agaactatgt tgactggata     1980

atgaagacta tgcaggaaaa tagcaccccc cgtgaggac                            2019


<210>  3199
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3199
tccgtgcagc tcacggagaa gcgaatggac aaagtcggca agtaccccaa ggagctgcgc       60

aagtgctgcg aggacggcat gcgggagaac cccatgaggt tctcgtgcca gcgccggacc      120

cgtttcatct ccctgggcga ggcgtgcaag aaggtcttcc tggactgctg caactacatc      180

acagagctgc ggcggcagca cgcgcgggcc agccacctgg gcctggccag g               231


<210>  3200
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3200
aacgtgaact tccaaaaggc gattaatgag aaattgggtc agtatgcttc cccgacagcc       60

aagcgctgct gccaggatgg ggtgacacgt ctgcccatga tgcgttcctg cgagcagcgg      120

gcagcccgcg tgcagcagcc ggactgctgg gagcccttcc tgtcctgctg ccaatttgct      180

gagagtctgc gcaagaagag cagggacaag ggccaggcgg gcctccaacg a               231


<210>  3201
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  3201
acgctgcaaa agaagataga agaaatagct gctaaatata aacattcagt agtgaagaaa       60

tgttgttacg atggagcctg cgttaataat gatgaaacct gtgagcagcg agctgcacgg      120

attagtttag ggccaagatg catcaaagct ttcactgaat gttgtgtcgt cgcaagccag      180

ctccgtgcta atatctctca taaagacatg caattgggaa gg                         222


<210>  3202
<211>  2739
<212>  DNA
<213>  Homo Sapiens

<400>  3202
tgcttctgtg atcactatgc atggactcag tggaccagct gctcaaaaac ttgcaattct       60

ggaacccaga gcagacacag acaaatagta gtagataagt actaccagga aaacttttgt      120

gaacagattt gcagcaagca ggagactaga gaatgtaact ggcaaagatg ccccatcaac      180

tgcctcctgg gagattttgg accatggtca gactgtgacc cttgtattga aaaacagtct      240

aaagttagat ctgtcttgcg tcccagtcag tttgggggac agccatgcac tgagcctctg      300

gtagcctttc aaccatgcat tccatctaag ctctgcaaaa ttgaagaggc tgactgcaag      360

aataaatttc gctgtgacag tggccgctgc attgccagaa agttagaatg caatggagaa      420

aatgactgtg gagacaattc agatgaaagg gactgtggga ggacaaaggc agtatgcaca      480

cggaagtata atcccatccc tagtgtacag ttgatgggca atgggtttca ttttctggca      540

ggagagccca gaggagaagt ccttgataac tctttcactg gaggaatatg taaaactgtc      600

aaaagcagta ggacaagtaa tccataccgt gttccggcca atctggaaaa tgtcggcttt      660

gaggtacaaa ctgcagaaga tgacttgaaa acagatttct acaaggattt aacttctctt      720

ggacacaatg aaaatcaaca aggctcattc tcaagtcagg gggggagctc tttcagtgta      780

ccaatttttt attcctcaaa gagaagtgaa aatatcaacc ataattctgc cttcaaacaa      840

gccattcaag cctctcacaa aaaggattct agttttatta ggatccataa agtgatgaaa      900

gtcttaaact tcacaacgaa agctaaagat ctgcaccttt ctgatgtctt tttgaaagca      960

cttaaccatc tgcctctaga atacaactct gctttgtaca gccgaatatt cgatgacttt     1020

gggactcatt acttcacctc tggctccctg ggaggcgtgt atgaccttct ctatcagttt     1080

agcagtgagg aactaaagaa ctcaggttta accgaggaag aagccaaaca ctgtgtcagg     1140

attgaaacaa agaaacgcgt tttatttgct aagaaaacaa aagtggaaca taggtgcacc     1200

accaacaagc tgtcagagaa acatgaaggt tcatttatac agggagcaga gaaatccata     1260

tccctgattc gaggtggaag gagtgaatat ggagcagctt tggcatggga gaaagggagc     1320

tctggtctgg aggagaagac attttctgag tggttagaat cagtgaagga aaatcctgct     1380

gtgattgact ttgagcttgc ccccatcgtg gacttggtaa gaaacatccc ctgtgcagtg     1440

acaaaacgga acaacctcag gaaagctttg caagagtatg cagccaagtt cgatccttgc     1500

cagtgtgctc catgccctaa taatggccga cccaccctct cagggactga atgtctgtgt     1560

gtgtgtcaga gtggcaccta tggtgagaac tgtgagaaac agtctccaga ttataaatcc     1620

aatgcagtag acggacagtg gggttgttgg tcttcctgga gtacctgtga tgctacttat     1680

aagagatcga gaacccgaga atgcaataat cctgcccccc aacgaggagg gaaacgctgt     1740

gagggggaga agcgacaaga ggaagactgc acattttcaa tcatggaaaa caatggacaa     1800

ccatgtatca atgatgatga agaaatgaaa gaggtcgatc ttcctgagat agaagcagat     1860

tccgggtgtc ctcagccagt tcctccagaa aatggattta tccggaatga aaagcaacta     1920

tacttggttg gagaagatgt tgaaatttca tgccttactg gctttgaaac tgttggatac     1980

cagtacttca gatgcttacc agacgggacc tggagacaag gggatgtgga atgccaacgg     2040

acggagtgca tcaagccagt tgtgcaggaa gtcctgacaa ttacaccatt tcagagattg     2100

tatagaattg gtgaatccat tgagctaact tgccccaaag gctttgttgt tgctgggcca     2160

tcaaggtaca catgccaggg gaattcctgg acaccaccca tttcaaactc tctcacctgt     2220

gaaaaagata ctctaacaaa attaaaaggc cattgtcagc tgggacagaa acaatcagga     2280

tctgaatgca tttgtatgtc tccagaagaa gactgtagcc atcattcaga agatctctgt     2340

gtgtttgaca cagactccaa cgattacttt acttcacccg cttgtaagtt tttggctgag     2400

aaatgtttaa ataatcagca actccatttt ctacatattg gttcctgcca agacggccgc     2460

cagttagaat ggggtcttga aaggacaaga ctttcatcca acagcacaaa gaaagaatcc     2520

tgtggctatg acacctgcta tgactgggaa aaatgttcag cctccacttc caaatgtgtc     2580

tgcctattgc ccccacagtg cttcaagggt ggaaaccaac tctactgtgt caaaatggga     2640

tcatcaacaa gtgagaaaac attgaacatc tgtgaagtgg gaactataag atgtgcaaac     2700

aggaagatgg aaatactgca tcctggaaag tgtttggcc                            2739


<210>  3203
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  3203
aaccctgggg cttctctgga cggccgccct ggggaccggg tgaatctctc ctgcggagga       60

gtctctcatc ccatccgctg ggtctgggca cccagcttcc cggcctgcaa gggcctgtcc      120

aaaggacgcc gaccgatcct gtgggcctct tcgagcggga cccccaccgt gcctcccctc      180

cagcctttcg tcggccgcct acgctccctg gactctggta tccggcggct ggagctcctc      240

ttgagcgcgg gggactcggg cacttttttc tgcaagggcc gccacgagga cgagagccgt      300

acagtgcttc acgtgctggg ggacaggacc tattgcaagg cccccgggcc tacccatggg      360

tccgtgtatc cccag                                                       375


<210>  3204
<211>  2463
<212>  DNA
<213>  Homo Sapiens

<400>  3204
tcctctccag tcaactgcca gtgggacttc tatgcccctt ggtcagaatg caatggctgt       60

accaagactc agactcgcag gcggtcagtt gctgtgtatg ggcagtatgg aggccagcct      120

tgtgttggaa atgcttttga aacacagtcc tgtgaaccta caagaggatg tccaacagag      180

gagggatgtg gagagcgttt caggtgcttt tcaggtcagt gcatcagcaa atcattggtt      240

tgcaatgggg attctgactg tgatgaagac agtgctgatg aagacagatg tgaggactca      300

gaaaggagac cttcctgtga tatcgataaa cctcctccta acatagaact tactggaaat      360

ggttacaatg aactcactgg ccagtttagg aacagagtca tcaataccaa aagttttggt      420

ggtcaatgta gaaaggtgtt tagtggggat ggaaaagatt tctacaggct gagtggaaat      480

gtcctgtcct atacattcca ggtgaaaata aataatgatt ttaattatga attttacaat      540

agtacttggt cttatgtaaa acatacgtcg acagaacaca catcatctag tcggaagcgc      600

tcctttttta gatcttcatc atcttcttca cgcagttata cttcacatac caatgaaatc      660

cataaaggaa agagttacca actgctggtt gttgagaaca ctgttgaagt ggctcagttc      720

attaataaca atccagaatt tttacaactt gctgagccat tctggaagga gctttcccac      780

ctcccctctc tgtatgacta cagtgcctac cgaagattaa tcgaccagta cgggacacat      840

tatctgcaat ctgggtcgtt aggaggagaa tacagagttc tattttatgt ggactcagaa      900

aaattaaaac aaaatgattt taattcagtc gaagaaaaga aatgtaaatc ctcaggttgg      960

cattttgtcg ttaaattttc aagtcatgga tgcaaggaac tggaaaacgc tttaaaagct     1020

gcttcaggaa cccagaacaa tgtattgcga ggagaaccgt tcatcagagg gggaggtgca     1080

ggcttcatat ctggccttag ttacctagag ctggacaatc ctgctggaaa caaaaggcga     1140

tattctgcct gggcagaatc tgtgactaat cttcctcaag tcataaaaca aaagctgaca     1200

cctttatatg agctggtaaa ggaagtacct tgtgcctctg tgaaaaaact atacctgaaa     1260

tgggctcttg aagagtatct ggatgaattt gacccctgtc attgccggcc ttgtcaaaat     1320

ggtggtttgg ctactgttga ggggacccat tgtctgtgcc attgcaaacc gtacacattt     1380

ggtgcggcgt gtgagcaagg agtcctcgta gggaatcaag caggaggggt tgatggaggt     1440

tggagttgct ggtcctcttg gagcccctgt gtccaaggga agaaaacaag aagccgtgaa     1500

tgcaataacc cacctcccag tgggggtggg agatcctgcg ttggagaaac gacagaaagc     1560

acacaatgcg aagatgagga gctggagcac ttgaggttgc ttgaaccaca ttgctttcct     1620

ttgtctttgg ttccaacaga attctgtcca tcacctcctg ccttgaaaga tggatttgtt     1680

caagatgaag gtacaatgtt tcctgtgggg aaaaatgtag tgtacacttg caatgaagga     1740

tactctctta ttggaaaccc agtggccaga tgtggagaag atttacggtg gcttgttggg     1800

gaaatgcatt gtcagaaaat tgcctgtgtt ctacctgtac tgatggatgg catacagagt     1860

cacccccaaa aacctttcta cacagttggt gagaaggtga ctgtttcctg ttcaggtggc     1920

atgtccttag aaggtccttc agcatttctc tgtggctcca gccttaagtg gagtcctgag     1980

atgaagaatg cccgctgtgt acaaaaagaa aatccgttaa cacaggcagt gcctaaatgt     2040

cagcgctggg agaaactgca gaattcaaga tgtgtttgta aaatgcccta cgaatgtgga     2100

ccttccttgg atgtatgtgc tcaagatgag agaagcaaaa ggatactgcc tctgacagtt     2160

tgcaagatgc atgttctcca ctgtcagggt agaaattaca cccttactgg tagggacagc     2220

tgtactctgc ctgcctcagc tgagaaagct tgtggtgcct gcccactgtg gggaaaatgt     2280

gatgctgaga gcagcaaatg tgtctgccga gaagcatcgg agtgcgagga agaagggttt     2340

agcatttgtg tggaagtgaa cggcaaggag cagacgatgt ctgagtgtga ggcgggcgct     2400

ctgagatgca gagggcagag catctctgtc accagcataa ggccttgtgc tgcggaaacc     2460

cag                                                                   2463


<210>  3205
<211>  1662
<212>  DNA
<213>  Homo Sapiens

<400>  3205
gcagctacac ccgcagcagt tacctgccag ctgagcaact ggtcagagtg gacagattgc       60

tttccgtgcc aggacaaaaa gtaccgacac cggagcctct tgcagccaaa caagtttggg      120

ggaaccatct gcagtggtga catctgggat caagccagct gctccagttc tacaacttgt      180

gtaaggaaag cacagtgtgg acaggatttc cagtgtaagg agacaggtcg ctgcctgaaa      240

cgccaccttg tgtgtaatgg agaccaggac tgccttgatg gctctgatga ggacgactgt      300

gaagatgtca gggccattga cgaagactgc agccagtatg aaccaattcc aggatcacag      360

aaggcagcct tggggtacaa tatcctgacc caggaagatg ctcagagtgt gtacgatgcc      420

agttattatg ggggccagtg tgagacggta tacaatgggg aatggaggga gcttcgatat      480

gactccacct gtgaacgtct ctactatgga gatgatgaga aatactttcg gaaaccctac      540

aactttctga agtaccactt tgaagccctg gcagatactg gaatctcctc agagttttat      600

gataatgcaa atgaccttct ttccaaagtt aaaaaagaca agtctgactc atttggagtg      660

accatcggca taggcccagc cggcagccct ttattggtgg gtgtaggtgt atcccactca      720

caagacactt cattcttgaa cgaattaaac aagtataatg agaagaaatt cattttcaca      780

agaatcttca caaaggtgca gactgcacat tttaagatga ggaaggatga cattatgctg      840

gatgaaggaa tgctgcagtc attaatggag cttccagatc agtacaatta tggcatgtat      900

gccaagttca tcaatgacta tggcacccat tacatcacat ctggatccat gggtggcatt      960

tatgaatata tcctggtgat tgacaaagca aaaatggaat cccttggtat taccagcaga     1020

gatatcacga catgttttgg aggctccttg ggcattcaat atgaagacaa aataaatgtt     1080

ggtggaggtt tatcaggaga ccattgtaaa aaatttggag gtggcaaaac tgaaagggcc     1140

aggaaggcca tggctgtgga agacattatt tctcgggtgc gaggtggcag ttctggctgg     1200

agcggtggct tggcacagaa caggagcacc attacatacc gttcctgggg gaggtcatta     1260

aagtataatc ctgttgttat cgattttgag atgcagccta tccacgaggt gctgcggcac     1320

acaagcctgg ggcctctgga ggccaagcgc cagaacctgc gccgcgcctt ggaccagtat     1380

ctgatggaat tcaatgcctg ccgatgtggg ccttgcttca acaatggggt gcccatcctc     1440

gagggcacca gctgcaggtg ccagtgccgc ctgggtagct tgggtgctgc ctgtgagcaa     1500

acacagacag aaggagccaa agcagatggg agctggagtt gctggagctc ctggtctgta     1560

tgcagagcag gcatccagga aaggagaaga gagtgtgaca atccagcacc tcagaatgga     1620

ggggcctcgt gtccagggcg gaaagtacag acgcaggctt gc                        1662


<210>  3206
<211>  1611
<212>  DNA
<213>  Homo Sapiens

<400>  3206
agtgtggatg ttaccctgat gcccattgat tgtgagctgt ctagttggtc ctcttggacc       60

acatgtgacc cctgtcagaa gaaaaggtac aggtatgcct acttgctcca gccctctcag      120

ttccatgggg aaccgtgcaa cttctctgac aaggaagtcg aagactgtgt taccaacaga      180

ccatgcagaa gtcaagtgcg atgtgaaggc tttgtgtgtg cacagacagg aaggtgtgta      240

aaccgcagac ttctttgcaa tggggacaat gactgtggag accagtcaga tgaagcaaac      300

tgtagaagga tttataaaaa atgtcagcat gaaatggacc aatactgggg aattggcagt      360

ctggccagtg ggataaattt gttcacaaac agttttgagg gcccagttct tgatcacagg      420

tattatgcag gtggatgctc cccgcattac atcctgaaca cgaggtttag gaagccctac      480

aatgtggaaa gctacacgcc acagacccaa ggcaaatacg aattcatatt aaaagagtat      540

gaatcatact cagattttga acgcaatgtc acagagaaaa tggcaagcaa gtctggtttc      600

agttttggtt ttaaaatacc tggaatattt gaacttggca tcagtagtca aagtgatcga      660

ggcaaacact atattaggag aaccaaacga ttctctcata ctaaaagcgt atttctgcat      720

gcacgctctg accttgaagt agcacattac aagctgaaac ccagaagcct catgctccat      780

tacgagttcc ttcagagagt taagcggctg cccctggagt acagctacgg ggaatacaga      840

gatctcttcc gtgattttgg gacccactac atcacagagg ctgtgcttgg gggcatttat      900

gaatacaccc tcgttatgaa caaagaggcc atggagagag gagattatac tcttaacaac      960

gtccatgcct gtgccaaaaa tgattttaaa attggtggtg ccattgaaga ggtctacgtc     1020

agtctgggtg tgtctgtagg caaatgcaga ggtattctga atgaaataaa agacagaaac     1080

aagagggaca ccatggtgga ggacttggtg gtcctggtac gaggaggggc aagtgagcac     1140

atcaccaccc tggcatacca ggagctgccg acggcggacc tgatgcagga gtggggagac     1200

gctgtgcagt acaacccagc catcatcaaa gttaaggtgg agcctctgta tgaactagtg     1260

acagccacag attttgccta ttccagcaca gtgaggcaga acatgaagca ggcactggag     1320

gagttccaga aggaagttag ttcctgccac tgtgctccct gccaaggaaa tggagtccct     1380

gtcctgaaag gatcacgctg tgactgcatc tgtcctgttg gatcccaagg cctagcctgt     1440

gaggtctcct atcggaagaa tacccccatt gatgggaagt ggaattgctg gtcaaattgg     1500

tcttcatgct ctggaagacg taagacaaga caaaggcagt gtaacaatcc acctcctcaa     1560

aatgggggta gcccctgttc aggccctgct tcagaaacac ttgactgctc c              1611


<210>  3207
<211>  732
<212>  DNA
<213>  Homo Sapiens

<400>  3207
cagtacacga ccagttatga cccagagcta acagaaagca gtggctctgc atcacacata       60

gactgcagaa tgagcccctg gagtgaatgg tcacaatgcg atccttgtct cagacaaatg      120

tttcgttcaa gaagcattga ggtctttgga caatttaatg ggaaaagatg caccgacgct      180

gtgggagaca gacgacagtg tgtgcccaca gagccctgtg aggatgctga ggatgactgc      240

ggaaatgact ttcaatgcag tacaggcaga tgcataaaga tgcgacttcg gtgtaatggt      300

gacaatgact gcggagactt ttcagatgag gatgattgtg aaagtgagcc ccgtcccccc      360

tgcagagaca gagtggtaga agagtctgag ctggcacgaa cagcaggcta tgggatcaac      420

attttaggga tggatcccct aagcacacct tttgacaatg agttctacaa tggactctgt      480

aaccgggatc gggatggaaa cactctgaca tactaccgaa gaccttggaa cgtggcttct      540

ttgatctatg aaaccaaagg cgagaaaaat ttcagaaccg aacattacga agaacaaatt      600

gaagcattta aaagtatcat ccaagagaag acatcaaatt ttaatgcagc tatatctcta      660

aaatttacac ccactgaaac aaataaagct gaacaatgtt gtgaggaaac agcctcctca      720

atttctttac at                                                          732


<210>  3208
<211>  906
<212>  DNA
<213>  Homo Sapiens

<400>  3208
cagaatctgt ttacgaaaga cgtgacagtg atcgagggag aggttgcgac catcagttgc       60

caagtcaata agagtgacga ctctgtgatt cagctactga atcccaacag gcagaccatt      120

tatttcaggg acttcaggcc tttgaaggac agcaggtttc agttgctgaa tttttctagc      180

agtgaactca aagtatcatt gacaaacgtc tcaatttctg atgaaggaag atacttttgc      240

cagctctata ccgatccccc acaggaaagt tacaccacca tcacagtcct ggtcccacca      300

cgtaatctga tgatcgatat ccagaaagac actgcggtgg aaggtgagga gattgaagtc      360

aactgcactg ctatggccag caagccagcc acgactatca ggtggttcaa agggaacaca      420

gagctaaaag gcaaatcgga ggtggaagag tggtcagaca tgtacactgt gaccagtcag      480

ctgatgctga aggtgcacaa ggaggacgat ggggtcccag tgatctgcca ggtggagcac      540

cctgcggtca ctggaaacct gcagacccag cggtatctag aagtacagta taagcctcaa      600

gtgcacattc agatgactta tcctctacaa ggcttaaccc gggaagggga cgcgcttgag      660

ttaacatgtg aagccatcgg gaagccccag cctgtgatgg taacttgggt gagagtcgat      720

gatgaaatgc ctcaacacgc cgtactgtct gggcccaacc tgttcatcaa taacctaaac      780

aaaacagata atggtacata ccgctgtgaa gcttcaaaca tagtggggaa agctcactcg      840

gattatatgc tgtatgtata cgattcccga gcaggtgaag aaggctcgat cagggcagtg      900

gatcat                                                                 906


<210>  3209
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3209
atgcctgtca aaacttccaa ggcatatctc accgttctgg gtgttcctga aaagcctcag       60

attagtggat tctcatcacc agttatggag ggtgacttga tgcagctgac ttgcaaaaca      120

tctggtagta aacctgcagc tgatataaga tggttcaaaa atgacaaaga gattaaagat      180

gtaaaatatt taaaagaaga ggatgcaaat cgcaagacat tcactgtcag cagcacactg      240

gacttccgag tggaccggag tgatgatgga gtggcggtca tctgcagagt agatcacgaa      300

tccctcaatg ccacccctca ggtagccatg caggtgctag aaatacacta tacaccatca      360

gttaagatta taccatcgac tccttttcca caagaaggac agcctttaat tttgacttgt      420

gaatccaaag gaaaaccact gccagaacct gttttgtgga caaaggatgg cggagaatta      480

ccagatcctg accgaatggt tgtgagtggt agggagctaa acattctttt cctgaacaaa      540

acggataatg gtacatatcg atgtgaagcc acaaacacca ttggccaaag cagtgcggaa      600

tatgttctca ttgtgcatga tcctaatgct ttggctggcc agaatggccc tgaccat         657


<210>  3210
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  3210
atggtgaaag ccggaacttg ctgtgccaca tgcaaggagt tctaccagat gaagcagacc       60

gtgctgcagc tgaagcaaaa gattgctctg ctccccaaca atgcagctga cctgggcaag      120

tatatcactg gtgacaaggt gctggcctca aacacctacc ttccaggacc tcctggcctg      180

cctgggggcc agggccctcc cggctcacca ggaccaaagg gaagcccagg cttccccggt      240

atgccaggcc ctcctgggca gcccggccca cggggctcaa tgggacccat gggaccatct      300

cctgatctgt cccacattaa gcaaggccgg aggggccctg tgggtccacc aggggcacca      360

ggaagagatg gttctaaggg ggagagagga gcgcctgggc ccagagggtc tccaggaccc      420

cctggttctt tcgacttcct gctacttatg ctggctgaca tccgcaatga catcactgag      480

ctgcaggaaa aggtgttcgg gcaccggact cactcttcag cagaggagtt ccctttacct      540

caggaatttc ccagctaccc agaagccatg gacctgggct ctggagatga ccatccaaga      600

agaactgaga caagagactt gagagccccc agagacttct accca                      645


<210>  3211
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3211
aagagcatgc aggtaccctt ctccagatgt tgcttctcat ttgcggagca agagattccc       60

ctgagggcaa tcctgtgtta cagaaatacc agctccatct gctccaatga gggcttaata      120

ttcaagctga agagaggcaa agaggcctgc gccttggaca cagttggatg ggttcagagg      180

cacagaaaaa tgctgaggca ctgcccgtca aaaagaaaa                             219


<210>  3212
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  3212
gggccagctt ctgtcccaac cacctgctgc tttaacctgg ccaataggaa gatacccctt       60

cagcgactag agagctacag gagaatcacc agtggcaaat gtccccagaa agctgtgatc      120

ttcaagacca aactggccaa ggatatctgt gccgacccca agaagaagtg ggtgcaggat      180

tccatgaagt atctggacca aaaatctcca actccaaagc ca                         222


<210>  3213
<211>  246
<212>  DNA
<213>  Homo Sapiens

<400>  3213
ttcaaccccc agggacttgc tcagccagat gcactcaacg tcccatctac ttgctgcttc       60

acatttagca gtaagaagat ctccttgcag aggctgaaga gctatgtgat caccaccagc      120

aggtgtcccc agaaggctgt catcttcaga accaaactgg gcaaggagat ctgtgctgac      180

ccaaaggaga agtgggtcca gaattatatg aaacacctgg gccggaaagc tcacaccctg      240

aagact                                                                 246


<210>  3214
<211>  198
<212>  DNA
<213>  Homo Sapiens

<400>  3214
ggaccttacc acccctcaga gtgctgcttc acctacacta cctacaagat cccgcgtcag       60

cggattatgg attactatga gaccaacagc cagtgctcca agcccggaat tgtcttcatc      120

accaaaaggg gccattccgt ctgtaccaac cccagtgaca agtgggtcca ggactatatc      180

aaggacatga aggagaac                                                    198


<210>  3215
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  3215
cagttcacaa atgatgcaga gacagagtta atgatgtcaa agcttccact ggaaaatcca       60

gtagttctga acagctttca ctttgctgct gactgctgca cctcctacat ctcacaaagc      120

atcccgtgtt cactcatgaa aagttatttt gaaacgagca gcgagtgctc caagccaggt      180

gtcatattcc tcaccaagaa ggggcggcaa gtctgtgcca aacccagtgg tccgggagtt      240

caggattgca tgaaaaagct gaagccctac tcaata                                276


<210>  3216
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  3216
cagccaaaag ttcctgagtg ggtgaacacc ccatccacct gctgcctgaa gtattatgag       60

aaagtgttgc caaggagact agtggtggga tacagaaagg ccctcaactg tcacctgcca      120

gcaatcatct tcgtcaccaa gaggaaccga gaagtctgca ccaaccccaa tgacgactgg      180

gtccaagagt acatcaagga tcccaaccta cctttgctgc ctaccaggaa cttgtccacg      240

gttaaaatta ttacagcaaa gaatggtcaa ccccagctcc tcaactccca g               291


<210>  3217
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  3217
gctcgaggga ccaatgtggg ccgggagtgc tgcctggagt acttcaaggg agccattccc       60

cttagaaagc tgaagacgtg gtaccagaca tctgaggact gctccaggga tgccatcgtt      120

tttgtaactg tgcagggcag ggccatctgt tcggacccca acaacaagag agtgaagaat      180

gcagttaaat acctacaaag ccttgagagg tct                                   213


<210>  3218
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3218
gcacaagttg gtaccaacaa agagctctgc tgcctcgtct atacctcctg gcagattcca       60

caaaagttca tagttgacta ttctgaaacc agcccccagt gccccaagcc aggtgtcatc      120

ctcctaacca agagaggccg gcagatctgt gctgacccca ataagaagtg ggtccagaaa      180

tacatcagcg acctgaagct gaatgcc                                          207


<210>  3219
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3219
ggcaccaatg atgctgaaga ctgctgcctg tctgtgaccc agaaacccat ccctgggtac       60

atcgtgagga acttccacta ccttctcatc aaggatggct gcagggtgcc tgctgtagtg      120

ttcaccacac tgaggggccg ccagctctgt gcacccccag accagccctg ggtagaacgc      180

atcatccaga gactgcagag gacctcagcc aagatgaagc gccgcagcag t               231


<210>  3220
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  3220
cagccagatg caatcaatgc cccagtcacc tgctgttata acttcaccaa taggaagatc       60

tcagtgcaga ggctcgcgag ctatagaaga atcaccagca gcaagtgtcc caaagaagct      120

gtgatcttca agaccattgt ggccaaggag atctgtgctg accccaagca gaagtgggtt      180

caggattcca tggaccacct ggacaagcaa acccaaactc cgaagact                   228


<210>  3221
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  3221
gcaagcaact ttgactgctg tcttggatac acagaccgta ttcttcatcc taaatttatt       60

gtgggcttca cacggcagct ggccaatgaa ggctgtgaca tcaatgctat catctttcac      120

acaaagaaaa agttgtctgt gtgcgcaaat ccaaaacaga cttgggtgaa atatattgtg      180

cgtctcctca gtaaaaaagt caagaacatg                                       210


<210>  3222
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  3222
agtgatggag gggctcagga ctgttgcctc aagtacagcc aaaggaagat tcccgccaag       60

gttgtccgca gctaccggaa gcaggaacca agcttaggct gctccatccc agctatcctg      120

ttcttgcccc gcaagcgctc tcaggcagag ctatgtgcag acccaaagga gctctgggtg      180

cagcagctga tgcagcatct ggacaagaca ccatccccac agaaaccagc ccagggctgc      240

aggaaggaca ggggggcctc caagactggc aagaaaggaa agggctccaa aggctgcaag      300

aggactgagc ggtcacagac ccctaaaggg cca                                   333


<210>  3223
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3223
ggcccctacg gcgccaacat ggaagacagc gtctgctgcc gtgattacgt ccgttaccgt       60

ctgcccctgc gcgtggtgaa acacttctac tggacctcag actcctgccc gaggcctggc      120

gtggtgttgc taaccttcag ggataaggag atctgtgccg atcccagagt gccctgggtg      180

aagatgattc tcaataagct gagccaa                                          207


<210>  3224
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  3224
aatccagtac ttctggacag attccatgct actagtgctg actgctgcat ctcctacacc       60

ccacgaagca tcccgtgttc actcctggag agttactttg aaacgaacag cgagtgctcc      120

aagccgggtg tcatcttcct caccaagaag gggcgacgtt tctgtgccaa ccccagtgat      180

aagcaagttc aggtttgcat gagaatgctg aagctggaca cacggatcaa gaccaggaag      240

aat                                                                    243


<210>  3225
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  3225
gtggtcatcc cctctccctg ctgcatgttc tttgtttcca agagaattcc tgagaaccga       60

gtggtcagct accagctgtc cagcaggagc atatgcctca aggcaggagt gatcttcacc      120

accaagaagg gccagcagtt ctgtggcgac cccaagcagg agtgggtcca gaggtacatg      180

aagaacctgg acgccaagca gaagaaggct tcccctaggg ccagggcagt ggctgtcaag      240

ggccctgtcc agagatatcc tggcaaccaa accacctgc                             279


<210>  3226
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  3226
caaggtgtct ttgaggactg ctgcctggcc taccactacc ccattgggtg ggctgtgctc       60

cggcgcgcct ggacttaccg gatccaggag gtgagcggga gctgcaatct gcctgctgcg      120

atattctacc tccccaagag acacaggaag gtgtgtggga accccaaaag cagggaggtg      180

cagagagcca tgaagctcct ggatgctcga aataaggttt ttgcaaagct ccaccacaac      240

acgcagacct tccaagcagg ccctcatgct gtaaagaagt tgagttctgg aaactccaag      300

ttatcatcat ccaagtttag caatcccatc agcagcagca agaggaatgt ctccctcctg      360

atatcagcta attcaggact g                                                381


<210>  3227
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  3227
acacgtggga gtgacatatc caagacctgc tgcttccaat acagccacaa gccccttccc       60

tggacctggg tgcgaagcta tgaattcacc agtaacagct gctcccagcg ggctgtgata      120

ttcactacca aaagaggcaa gaaagtctgt acccatccaa ggaaaaaatg ggtgcaaaaa      180

tacatttctt tactgaaaac tccgaaacaa ttg                                   213


<210>  3228
<211>  264
<212>  DNA
<213>  Homo Sapiens

<400>  3228
ttcctactgc cacccagcac tgcctgctgt actcagctct accgaaagcc actctcagac       60

aagctactga ggaaggtcat ccaggtggaa ctgcaggagg ctgacgggga ctgtcacctc      120

caggctttcg tgcttcacct ggctcaacgc agcatctgca tccaccccca gaaccccagc      180

ctgtcacagt ggtttgagca ccaagagaga aagctccatg ggactctgcc caagctgaat      240

tttgggatgc taaggaaaat gggc                                             264


<210>  3229
<211>  324
<212>  DNA
<213>  Homo Sapiens

<400>  3229
tcagaagcca tacttcccat tgcctccagc tgttgcacgg aggtttcaca tcatatttcc       60

agaaggctcc tggaaagagt gaatatgtgt cgcatccaga gagctgatgg ggattgtgac      120

ttggctgctg tcatccttca tgtcaagcgc agaagaatct gtgtcagccc gcacaaccat      180

actgttaagc agtggatgaa agtgcaagct gccaagaaaa atggtaaagg aaatgtttgc      240

cacaggaaga aacaccatgg caagaggaac agtaacaggg cacatcaggg gaaacacgaa      300

acatacggcc ataaaactcc ttat                                             324


<210>  3230
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3230
tcacttgctg ctgacacgcc gaccgcctgc tgcttcagct acacctcccg gcagattcca       60

cagaatttca tagctgacta ctttgagacg agcagccagt gctccaagcc tggtgtcatc      120

ttcctaacca agcgaagccg gcaggtctgt gctgacccca gtgaggagtg ggtccagaaa      180

tatgtcagcg acctggagct gagtgcc                                          207


<210>  3231
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  3231
cttgctgctg acacgccgac cgcctgctgc ttcagctaca cctcccggca gattccacag       60

aatttcatag ctgactactt tgagacgagc agccagtgct ccaagcccag tgtcatcttc      120

ctaaccaaga gaggccggca ggtctgtgct gaccccagtg aggagtgggt ccagaaatac      180

gtcagtgacc tggagccgag tgcc                                             204


<210>  3232
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3232
gcaccaatgg gctcagaccc tcccaccgcc tgctgctttt cttacaccgc gaggaagctt       60

cctcgcaact ttgtggtaga ttactatgag accagcagcc tctgctccca gccagctgtg      120

gtattccaaa ccaaaagaag caagcaagtc tgtgctgatc ccagtgaatc ctgggtccag      180

gagtacgtgt atgacctgga actgaac                                          207


<210>  3233
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3233
gcaccaatgg gctcagaccc tcccaccgcc tgctgctttt cttacaccgc gaggaagctt       60

cctcacaact ttgtggtaga ttactatgag accagcagcc tctgctccca gccagctgtg      120

gtattccaaa ccaaaagagg caagcaagtc tgcgccgacc ccagtgagtc ctgggtccag      180

gagtacgtgt atgacctgga actgaac                                          207


<210>  3234
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  3234
tccccatatt cctcggacac cacaccctgc tgctttgcct acattgcccg cccactgccc       60

cgtgcccaca tcaaggagta tttctacacc agtggcaagt gctccaaccc agcagtcgtc      120

tttgtcaccc gaaagaaccg ccaagtgtgt gccaacccag agaagaaatg ggttcgggag      180

tacatcaact ctttggagat gagc                                             204


<210>  3235
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  3235
cagccagttg ggattaatac ttcaactacc tgctgctaca gatttatcaa taagaaaatc       60

cctaagcaga ggctggagag ctacagaagg accaccagta gccactgtcc ccgggaagct      120

gtaatcttca agaccaaact ggacaaggag atctgtgctg accccacaca gaagtgggtc      180

caggacttta tgaagcacct ggacaagaaa acccaaactc caaagctt                   228


<210>  3236
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  3236
cagccagatt cagtttccat tccaatcacc tgctgcttta acgtgatcaa taggaaaatt       60

cctatccaga ggctggagag ctacacaaga atcaccaaca tccaatgtcc caaggaagct      120

gtgatcttca agacccaacg gggcaaggag gtctgtgctg accccaagga gagatgggtc      180

agggattcca tgaagcatct ggaccaaata tttcaaaatc tgaagcca                   228


<210>  3237
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  3237
accacgccag aaccttgtga gctggacgat gaagatttcc gctgcgtctg caacttctcc       60

gaacctcagc ccgactggtc cgaagccttc cagtgtgtgt ctgcagtaga ggtggagatc      120

catgccggcg gtctcaacct agagccgttt ctaaagcgcg tcgatgcgga cgccgacccg      180

cggcagtatg ctgacacggt caaggctctc cgcgtgcggc ggctcacagt gggagccgca      240

caggttcctg ctcagctact ggtaggcgcc ctgcgtgtgc tagcgtactc ccgcctcaag      300

gaactgacgc tcgaggacct aaagataacc ggcaccatgc ctccgctgcc tctggaagcc      360

acaggacttg cactttccag cttgcgccta cgcaacgtgt cgtgggcgac agggcgttct      420

tggctcgccg agctgcagca gtggctcaag ccaggcctca aggtactgag cattgcccaa      480

gcacactcgc ctgccttttc ctgcgaacag gttcgcgcct tcccggccct taccagccta      540

gacctgtctg acaatcctgg actgggcgaa cgcggactga tggcggctct ctgtccccac      600

aagttcccgg ccatccagaa tctagcgctg cgcaacacag gaatggagac gcccacaggc      660

gtgtgcgccg cactggcggc ggcaggtgtg cagccccaca gcctagacct cagccacaac      720

tcgctgcgcg ccaccgtaaa ccctagcgct ccgagatgca tgtggtccag cgccctgaac      780

tccctcaatc tgtcgttcgc tgggctggaa caggtgccta aaggactgcc agccaagctc      840

agagtgctcg atctcagctg caacagactg aacagggcgc cgcagcctga cgagctgccc      900

gaggtggata acctgacact ggacgggaat cccttcctgg tccctggaac tgccctcccc      960

cacgagggct caatgaac                                                    978


<210>  3238
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  3238
gcctactacc agcagctgaa cacggagctc aaggagaacc tgaaggacac catgaccaag       60

cgctaccacc agccgggcca tgaggctgtg accagcgctg tggaccagct gcagcaggag      120

ttccactgct gtggcagcaa caactcacag gactggcgag acagtgagtg gatccgctca      180

caggaggccg gtggccgtgt ggtcccagac agctgctgca agacggtggt ggctctttgt      240

ggacagcgag accatgcctc caacatctac aaggtggagg gcggctgcat caccaagttg      300

gagaccttca tccaggagca cctgagg                                          327


<210>  3239
<211>  3027
<212>  DNA
<213>  Homo Sapiens

<400>  3239
agttctcttg gaggaacaga caaggagctg aggctagtgg atggtgaaaa caagtgtagc       60

gggagagtgg aagtgaaagt ccaggaggag tggggaacgg tgtgtaataa tggctggagc      120

atggaagcgg tctctgtgat ttgtaaccag ctgggatgtc caactgctat caaagcccct      180

ggatgggcta attccagtgc aggttctgga cgcatttgga tggatcatgt ttcttgtcgt      240

gggaatgagt cagctctttg ggattgcaaa catgatggat ggggaaagca tagtaactgt      300

actcaccaac aagatgctgg agtgacctgc tcagatggat ccaatttgga aatgaggctg      360

acgcgtggag ggaatatgtg ttctggaaga atagagatca aattccaagg acggtgggga      420

acagtgtgtg atgataactt caacatagat catgcatctg tcatttgtag acaacttgaa      480

tgtggaagtg ctgtcagttt ctctggttca tctaattttg gagaaggctc tggaccaatc      540

tggtttgatg atcttatatg caacggaaat gagtcagctc tctggaactg caaacatcaa      600

ggatggggaa agcataactg tgatcatgct gaggatgctg gagtgatttg ctcaaaggga      660

gcagatctga gcctgagact ggtagatgga gtcactgaat gttcaggaag attagaagtg      720

agattccaag gagaatgggg gacaatatgt gatgacggct gggacagtta cgatgctgct      780

gtggcatgca agcaactggg atgtccaact gccgtcacag ccattggtcg agttaacgcc      840

agtaagggat ttggacacat ctggcttgac agcgtttctt gccagggaca tgaacctgct      900

gtctggcaat gtaaacacca tgaatgggga aagcattatt gcaatcacaa tgaagatgct      960

ggcgtgacat gttctgatgg atcagatctg gagctaagac ttagaggtgg aggcagccgc     1020

tgtgctggga cagttgaggt ggagattcag agactgttag ggaaggtgtg tgacagaggc     1080

tggggactga aagaagctga tgtggtttgc aggcagctgg gatgtggatc tgcactcaaa     1140

acatcttatc aagtgtactc caaaatccag gcaacaaaca catggctgtt tctaagtagc     1200

tgtaacggaa atgaaacttc tctttgggac tgcaagaact ggcaatgggg tggacttacc     1260

tgtgatcact atgaagaagc caaaattacc tgctcagccc acagggaacc cagactggtt     1320

ggaggggaca ttccctgttc tggacgtgtt gaagtgaagc atggtgacac gtggggctcc     1380

atctgtgatt cggacttctc tctggaagct gccagcgttc tatgcaggga attacagtgt     1440

ggcacagttg tctctatcct ggggggagct cactttggag agggaaatgg acagatctgg     1500

gctgaagaat tccagtgtga gggacatgag tcccatcttt cactctgccc agtagcaccc     1560

cgcccagaag gaacttgtag ccacagcagg gatgttggag tagtctgctc aagatacaca     1620

gaaattcgct tggtgaatgg caagaccccg tgtgagggca gagtggagct caaaacgctt     1680

ggtgcctggg gatccctctg taactctcac tgggacatag aagatgccca tgttctttgc     1740

cagcagctta aatgtggagt tgccctttct accccaggag gagcacgttt tggaaaagga     1800

aatggtcaga tctggaggca tatgtttcac tgcactggga ctgagcagca catgggagat     1860

tgtcctgtaa ctgctctagg tgcttcatta tgtccttcag agcaagtggc ctctgtaatc     1920

tgctcaggaa accagtccca aacactgtcc tcgtgcaatt catcgtcttt gggcccaaca     1980

aggcctacca ttccagaaga aagtgctgtg gcctgcatag agagtggtca acttcgcctg     2040

gtaaatggag gaggtcgctg tgctgggaga gtagagatct atcatgaggg ctcctggggc     2100

accatctgtg atgacagctg ggacctgagt gatgcccacg tggtttgcag acagctgggc     2160

tgtggagagg ccattaatgc cactggttct gctcattttg gggaaggaac agggcccatc     2220

tggctggatg agatgaaatg caatggaaaa gaatcccgca tttggcagtg ccattcacac     2280

ggctgggggc agcaaaattg caggcacaag gaggatgcgg gagttatctg ctcagaattc     2340

atgtctctga gactgaccag tgaagccagc agagaggcct gtgcagggcg tctggaagtt     2400

ttttacaatg gagcttgggg cactgttggc aagagtagca tgtctgaaac cactgtgggt     2460

gtggtgtgca ggcagctggg ctgtgcagac aaagggaaaa tcaaccctgc atctttagac     2520

aaggccatgt ccattcccat gtgggtggac aatgttcagt gtccaaaagg acctgacacg     2580

ctgtggcagt gcccatcatc tccatgggag aagagactgg ccagcccctc ggaggagacc     2640

tggatcacat gtgacaacaa gataagactt caggaaggac ccacttcctg ttctggacgt     2700

gtggagatct ggcatggagg ttcctggggg acagtgtgtg atgactcttg ggacttggac     2760

gatgctcagg tggtgtgtca acaacttggc tgtggtccag ctttgaaagc attcaaagaa     2820

gcagagtttg gtcaggggac tggaccgata tggctcaatg aagtgaagtg caaagggaat     2880

gagtcttcct tgtgggattg tcctgccaga cgctggggcc atagtgagtg tgggcacaag     2940

gaagacgctg cagtgaattg cacagatatt tcagtgcaga aaaccccaca aaaagccaca     3000

acaggtcgct catcccgtca gtcatcc                                         3027


<210>  3240
<211>  3957
<212>  DNA
<213>  Homo Sapiens

<400>  3240
tttaatggaa cagatttgga gttgaggctg gtcaatggag acggtccctg ctctgggaca       60

gtggaggtga aattccaggg acagtggggg actgtgtgtg atgatgggtg gaacactact      120

gcctcaactg tcgtgtgcaa acagcttgga tgtccatttt ctttcgccat gtttcgtttt      180

ggacaagccg tgactagaca tggaaaaatt tggcttgatg atgtttcctg ttatggaaat      240

gagtcagctc tctgggaatg tcaacaccgg gaatggggaa gccataactg ttatcatgga      300

gaagatgttg gtgtgaactg ttacggtgaa gccaatctgg gtttgaggct agtggatgga      360

aacaactcct gttcagggag agtggaggtg aaattccaag aaaggtgggg aactatatgt      420

gatgatgggt ggaacttgaa tactgctgcc gtggtgtgca ggcaactagg atgtccatct      480

tcttttattt cttctggagt tgttaatagc cctgctgtat tgcgccccat ttggctggat      540

gacattttat gccaggggaa tgagttggca ctctggaatt gcagacatcg tggatgggga      600

aatcatgact gcagtcacaa tgaggatgtc acattaactt gttatgatag tagtgatctt      660

gaactaaggc ttgtaggtgg aactaaccgc tgtatgggga gagtagagct gaaaatccaa      720

ggaaggtggg ggaccgtatg ccaccataag tggaacaatg ctgcagctga tgtcgtatgc      780

aagcagttgg gatgtggaac cgcacttcac ttcgctggct tgcctcattt gcagtcaggg      840

tctgatgttg tatggcttga tggtgtctcc tgctccggta atgaatcttt tctttgggac      900

tgcagacatt ccggaaccgt caattttgac tgtcttcatc aaaacgatgt gtctgtgatc      960

tgctcagatg gagcagattt ggaactgcga ctagcagatg gaagtaacaa ttgttcaggg     1020

agagtagagg tgagaattca tgaacagtgg tggacaatat gtgaccagaa ctggaagaat     1080

gaacaagccc ttgtggtttg taagcagcta ggatgtccgt tcagcgtctt tggcagtcgt     1140

cgtgctaaac ctagtaatga agctagagac atttggataa acagcatatc ttgcactggg     1200

aatgagtcag ctctctggga ctgcacatat gatggaaaag caaagcgaac atgcttccga     1260

agatcagatg ctggagtaat ttgttctgat aaggcagatc tggacctaag gcttgtcggg     1320

gctcatagcc cctgttatgg gagattggag gtgaaatacc aaggagagtg ggggactgtg     1380

tgtcatgaca gatggagcac aaggaatgca gctgttgtgt gtaaacaatt gggatgtgga     1440

aagcctatgc atgtgtttgg tatgacctat tttaaagaag catcaggacc tatttggctg     1500

gatgacgttt cttgcattgg aaatgagtca aatatctggg actgtgaaca cagtggatgg     1560

ggaaagcata attgtgtaca cagagaggat gtgattgtaa cctgctcagg tgatgcaaca     1620

tggggcctga ggctggtggg cggcagcaac cgctgctcgg gaagactgga ggtgtacttt     1680

caaggacggt ggggcacagt gtgtgatgac ggctggaaca gtaaagctgc agctgtggtg     1740

tgtagccagc tggactgccc atcttctatc attggcatgg gtctgggaaa cgcttctaca     1800

ggatatggaa aaatttggct cgatgatgtt tcctgtgatg gagatgagtc agatctctgg     1860

tcatgcagga acagtgggtg gggaaataat gactgcagtc acagtgaaga tgttggagtg     1920

atctgttctg atgcatcgga tatggagctg aggcttgtgg gtggaagcag caggtgtgct     1980

ggaaaagttg aggtgaatgt ccagggtgcc gtgggaattc tgtgtgctaa tggctgggga     2040

atgaacattg ctgaagttgt ttgcaggcaa cttgaatgtg ggtctgcaat cagggtctcc     2100

agagagcctc atttcacaga aagaacatta cacatcttaa tgtcgaattc tggctgcact     2160

ggaggggaag cctctctctg ggattgtata cgatgggagt ggaaacagac tgcgtgtcat     2220

ttaaatatgg aagcaagttt gatctgctca gcccacaggc agcccaggct ggttggagct     2280

gatatgccct gctctggacg tgttgaagtg aaacatgcag acacatggcg ctctgtctgt     2340

gattctgatt tctctcttca tgctgccaat gtgctgtgca gagaattaaa ctgtggagat     2400

gccatatctc tttctgtggg agatcacttt ggaaaaggga atggtctaac ttgggccgaa     2460

aagttccagt gtgaagggag tgaaactcac cttgcattat gccccattgt tcaacatccg     2520

gaagacactt gtatccacag cagagaagtt ggagttgtct gttcccgata tacagatgtc     2580

cgacttgtga atggcaaatc ccagtgtgac gggcaagtgg agatcaacgt gcttggacac     2640

tggggctcac tgtgtgacac ccactgggac ccagaagatg cccgtgttct atgcagacag     2700

ctcagctgtg ggactgctct ctcaaccaca ggaggaaaat atattggaga aagaagtgtt     2760

cgtgtgtggg gacacaggtt tcattgctta gggaatgagt cacttctgga taactgtcaa     2820

atgacagttc ttggagcacc tccctgtatc catggaaata ctgtctctgt gatctgcaca     2880

ggaagcctga cccagccact gtttccatgc ctcgcaaatg tatctgaccc atatttgtct     2940

gcagttccag agggcagtgc tttgatctgc ttagaggaca aacggctccg cctagtggat     3000

ggggacagcc gctgtgccgg gagagtagag atctatcacg acggcttctg gggcaccatc     3060

tgtgatgacg gctgggacct gagcgatgcc cacgtggtgt gtcaaaagct gggctgtgga     3120

gtggccttca atgccacggt ctctgctcac tttggggagg ggtcagggcc catctggctg     3180

gatgacctga actgcacagg aatggagtcc cacttgtggc agtgcccttc ccgcggctgg     3240

gggcagcacg actgcaggca caaggaggac gcaggggtca tctgctcaga attcacagcc     3300

ttgaggctct acagtgaaac tgaaacagag agctgtgctg ggagattgga agtcttctat     3360

aacgggacct ggggcagcgt cggcaggagg aacatcacca cagccatagc aggcattgtg     3420

tgcaggcagc tgggctgtgg ggagaatgga gttgtcagcc tcgccccttt atctaagaca     3480

ggctctggtt tcatgtgggt ggatgacatt cagtgtccta aaacgcatat ctccatatgg     3540

cagtgcctgt ctgccccatg ggagcgaaga atctccagcc cagcagaaga gacctggatc     3600

acatgtgaag atagaataag agtgcgtgga ggagacaccg agtgctctgg gagagtggag     3660

atctggcacg caggctcctg gggcacagtg tgtgatgact cctgggacct ggccgaggcg     3720

gaagtggtgt gtcagcagct gggctgtggc tctgctctgg ctgccctgag ggacgcttcg     3780

tttggccagg gaactggaac catctggttg gatgacatgc ggtgcaaagg aaatgagtca     3840

tttctatggg actgtcacgc caaaccctgg ggacagagtg actgtggaca caaggaagat     3900

gctggcgtga ggtgctctgg acagtcgctg aaatcactga atgcctcctc aggtcat        3957


<210>  3241
<211>  1809
<212>  DNA
<213>  Homo Sapiens

<400>  3241
tgggatcaga tgtgcattga gaaagaagcc aacaaaacat ataactgtga aaatttaggt       60

ctcagtgaaa tccctgacac tctaccaaac acaacagaat ttttggaatt cagctttaat      120

tttttgccta caattcacaa tagaaccttc agcagactca tgaatcttac ctttttggat      180

ttaactaggt gccagattaa ctggatacat gaagacactt ttcaaagcca tcatcaatta      240

agcacacttg tgttaactgg aaatcccctg atattcatgg cagaaacatc gcttaatggg      300

cccaagtcac tgaagcatct tttcttaatc caaacgggaa tatccaatct cgagtttatt      360

ccagtgcaca atctggaaaa cttggaaagc ttgtatcttg gaagcaacca tatttcctcc      420

attaagttcc ccaaagactt cccagcacgg aatctgaaag tactggattt tcagaataat      480

gctatacact acatctctag agaagacatg aggtctctgg agcaggccat caacctaagc      540

ctgaacttca atggcaataa tgttaaaggt attgagcttg gggcttttga ttcaacggtc      600

ttccaaagtt tgaactttgg aggaactcca aatttgtctg ttatattcaa tggtctgcag      660

aactctacta ctcagtctct ctggctggga acatttgagg acattgatga cgaagatatt      720

agttcagcca tgctcaaggg actctgtgaa atgtctgttg agagcctcaa cctgcaggaa      780

caccgcttct ctgacatctc atccaccaca tttcagtgct tcacccaact ccaagaattg      840

gatctgacag caactcactt gaaagggtta ccctctggga tgaagggtct gaacttgctc      900

aagaaattag ttctcagtgt aaatcatttc gatcaattgt gtcaaatcag tgctgccaat      960

ttcccctccc ttacacacct ctacatcaga ggcaacgtga agaaacttca ccttggtgtt     1020

ggctgcttgg agaaactagg aaaccttcag acacttgatt taagccataa tgacatagag     1080

gcttctgact gctgcagtct gcaactcaaa aacctgtccc acttgcaaac cttaaacctg     1140

agccacaatg agcctcttgg tctccagagt caggcattca aagaatgtcc tcagctagaa     1200

ctcctcgatt tggcatttac ccgcttacac attaatgctc cacaaagtcc cttccaaaac     1260

ctccatttcc ttcaggttct gaatctcact tactgcttcc ttgataccag caatcagcat     1320

cttctagcag gcctaccagt tctccggcat ctcaacttaa aagggaatca ctttcaagat     1380

gggactatca cgaagaccaa cctacttcag accgtgggca gcttggaggt tctgattttg     1440

tcctcttgtg gtctcctctc tatagaccag caagcattcc acagcttggg aaaaatgagc     1500

catgtagact taagccacaa cagcctgaca tgcgacagca ttgattctct tagccatctt     1560

aagggaatct acctcaatct ggctgccaac agcattaaca tcatctcacc ccgtctcctc     1620

cctatcttgt cccagcagag caccattaat ttaagtcata accccctgga ctgcacttgc     1680

tcgaatattc atttcttaac atggtacaaa gaaaacctgc acaaacttga aggctcggag     1740

gagaccacgt gtgcaaaccc gccatctcta aggggagtta agctatctga tgtcaagctt     1800

tcctgtggg                                                             1809


<210>  3242
<211>  816
<212>  DNA
<213>  Homo Sapiens

<400>  3242
cccgaggaac ctctagtggt gaaggtggaa gagggagata acgctgtgct gcagtgcctc       60

aaggggacct cagatggccc cactcagcag ctgacctggt ctcgggagtc cccgcttaaa      120

cccttcttaa aactcagcct ggggctgcca ggcctgggaa tccacatgag gcccctggcc      180

atctggcttt tcatcttcaa cgtctctcaa cagatggggg gcttctacct gtgccagccg      240

gggcccccct ctgagaaggc ctggcagcct ggctggacag tcaatgtgga gggcagcggg      300

gagctgttcc ggtggaatgt ttcggaccta ggtggcctgg gctgtggcct gaagaacagg      360

tcctcagagg gccccagctc cccttccggg aagctcatga gccccaagct gtatgtgtgg      420

gccaaagacc gccctgagat ctgggaggga gagcctccgt gtctcccacc gagggacagc      480

ctgaaccaga gcctcagcca ggacctcacc atggcccctg gctccacact ctggctgtcc      540

tgtggggtac cccctgactc tgtgtccagg ggccccctct cctggaccca tgtgcacccc      600

aaggggccta agtcattgct gagcctagag ctgaaggacg atcgcccggc cagagatatg      660

tgggtaatgg agacgggtct gttgttgccc cgggccacag ctcaagacgc tggaaagtat      720

tattgtcacc gtggcaacct gaccatgtca ttccacctgg agatcactgc tcggccagta      780

ctatggcact ggctgctgag gactggtggc tggaag                                816


<210>  3243
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  3243
ctcaaggagc ctctctcctt ccatgtcatc tggatcgcat ccttttacaa ccattcctgg       60

aaacaaaatc tggtctcagg ttggctgagt gatttgcaga ctcatacctg ggacagcaat      120

tccagcacca tcgttttcct gtggccctgg tccaggggaa acttcagcaa tgaggagtgg      180

aaggaactgg aaacattatt ccgtatacgc accattcggt catttgaggg aattcgtaga      240

tacgcccatg aattgcagtt tgaatatcct tttgagatac aggtgacagg aggctgtgag      300

ctgcactctg gaaaggtctc aggaagcttc ttgcagttag cttatcaagg atcagacttt      360

gtgagcttcc agaacaattc atggttgcca tatccagtgg ctgggaatat ggccaagcat      420

ttctgcaaag tgctcaatca gaatcagcat gaaaatgaca taacacacaa tcttctcagt      480

gacacctgcc cacgtttcat cttgggtctt cttgatgcag gaaaggcaca tctccagcgg      540

caagtgaagc ccgaggcctg gctgtcccat ggccccagtc ctggccctgg ccatctgcag      600

cttgtgtgcc atgtctcagg attctaccca aagcccgtgt gggtgatgtg gatgcggggt      660

gagcaggagc agcagggcac tcagcgaggg gacatcttgc ccagtgctga tgggacatgg      720

tatctccgcg caaccctgga ggtggccgct ggggaggcag ctgacctgtc ctgtcgggtg      780

aagcacagca gtctagaggg ccaggacatc gtcctctact gggagcatca cagttccgtg      840


<210>  3244
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  3244
agtgaacatg ccttccaggg gccgacctcc tttcatgtta tccagacctc gtcctttacc       60

aatagtacct gggcacaaac tcaaggctca ggctggttgg atgatttgca gattcatggc      120

tgggatagcg actcaggcac tgccatattc ctgaagcctt ggtctaaagg taactttagt      180

gataaggagg ttgctgagtt agaggagata ttccgagtct acatctttgg attcgctcga      240

gaagtacaag actttgccgg tgatttccag atgaaatacc cctttgagat ccagggcata      300

gcaggctgtg agctacattc tggaggtgcc atagtaagct tcctgagggg agctctagga      360

ggattggatt tcctgagtgt caagaatgct tcatgtgtgc cttccccaga aggtggcagc      420

agggcacaga aattctgtgc actaatcata caatatcaag gtatcatgga aactgtgaga      480

attctcctct atgaaacctg cccccgatat ctcttgggcg tcctcaatgc aggaaaagca      540

gatctgcaaa gacaagtgaa gcctgaggcc tggctgtcca gtggccccag tcctggacct      600

ggccgtctgc agcttgtgtg ccatgtctca ggattctacc caaagcccgt gtgggtgatg      660

tggatgcggg gtgagcagga gcagcagggc actcagctag gggacatcct gcccaatgct      720

aactggacat ggtatctccg agcaaccctg gatgtggcag atggggaggc ggctggcctg      780

tcctgtcggg tgaagcacag cagtttagag ggccaggaca tcatcctcta ctggagaaac      840

cccacctcca ttggctca                                                    858


<210>  3245
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  3245
aatgcagacg catcccagga acacgtctcc ttccatgtca tccagatctt ctcatttgtc       60

aaccaatcct gggcacgagg tcagggctca ggatggctgg acgagttgca gactcatggc      120

tgggacagtg aatcaggcac aataattttc ctgcataact ggtccaaggg caacttcagc      180

aatgaagagt tgtcagacct agagttgtta tttcgtttct acctctttgg attaactcgg      240

gagattcaag accatgcaag tcaagattac tcgaaatatc cctttgaagt acaggtgaaa      300

gcgggctgtg agctgcattc tggaaagagc ccagaaggct tctttcaggt agctttcaac      360

ggattagatt tactgagttt ccagaataca acatgggtgc catctccagg ctgtggaagt      420

ttggcccaaa gtgtctgtca tctactcaat catcagtatg aaggcgtcac agaaacagtg      480

tataatctca taagaagcac ttgcccccga tttctcttgg gtctcctgga tgcagggaag      540

atgtatgtac acaggcaagt gaggccagaa gcctggctgt ccagtcgccc cagccttggg      600

tctggccagc tgttgctggt ttgtcatgcc tccggcttct acccaaagcc tgtttgggtg      660

acatggatgc ggaatgaaca ggagcaactg ggcactaaac atggtgatat tcttcctaat      720

gctgatggga catggtatct tcaggtgatc ctggaggtgg catctgagga gcctgctggc      780

ctgtcttgtc gagtgagaca cagcagtcta ggaggccagg acatcatcct ctactgggga      840

caccactttt ccatg                                                       855


<210>  3246
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  3246
gaagtcccgc aaaggctttt ccccctccgc tgcctccaga tctcgtcctt cgccaatagc       60

agctggacgc gcaccgacgg cttggcgtgg ctgggggagc tgcagacgca cagctggagc      120

aacgactcgg acaccgtccg ctctctgaag ccttggtccc agggcacgtt cagcgaccag      180

cagtgggaga cgctgcagca tatatttcgg gtttatcgaa gcagcttcac cagggacgtg      240

aaggaattcg ccaaaatgct acgcttatcc tatcccttgg agctccaggt gtccgctggc      300

tgtgaggtgc accctgggaa cgcctcaaat aacttcttcc atgtagcatt tcaaggaaaa      360

gatatcctga gtttccaagg aacttcttgg gagccaaccc aagaggcccc actttgggta      420

aacttggcca ttcaagtgct caaccaggac aagtggacga gggaaacagt gcagtggctc      480

cttaatggca cctgccccca atttgtcagt ggcctccttg agtcagggaa gtcggaactg      540

aagaagcaag tgaagcccaa ggcctggctg tcccgtggcc ccagtcctgg ccctggccgt      600

ctgctgctgg tgtgccatgt ctcaggattc tacccaaagc ctgtatgggt gaagtggatg      660

cggggtgagc aggagcagca gggcactcag ccaggggaca tcctgcccaa tgctgacgag      720

acatggtatc tccgagcaac cctggatgtg gtggctgggg aggcagctgg cctgtcctgt      780

cgggtgaagc acagcagtct agagggccag gacatcgtcc tctactgggg tgggagctac      840

acctcc                                                                 846


<210>  3247
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  3247
gctccccagg ctctacaatc ctatcatcta gcagcagagg agcagctgtc cttccgcatg       60

ctccaaactt cctcctttgc caaccacagc tgggcacaca gtgagggctc aggatggctg      120

ggtgacctgc agactcatgg ctgggacact gtcttgggca ccatccgctt tctgaagccc      180

tggtcccatg gaaacttcag caagcaggag ctgaaaaact tacagtcact gttccagtta      240

tacttccata gttttatcca gatagtgcaa gcttctgctg gtcaatttca gcttgaatac      300

cccttcgaga tccagatatt agctggctgt agaatgaatg ccccacaaat cttcttaaat      360

atggcatatc aagggtcaga tttcctgagt ttccaaggaa tttcctggga gccatctcca      420

ggagcaggga tccgggccca gaacatctgt aaagtgctca atcgctacct agatattaag      480

gaaatactgc aaagccttct tggtcacacc tgccctcgat ttctagcggg gctcatggaa      540

gcaggggagt cagaactgaa acggaaagtg aagccagagg cctggctgtc ctgtggcccc      600

agtcctggcc ctggccgtct gcagcttgtg tgccatgtct caggattcta cccaaagccc      660

gtgtgggtga tgtggatgcg gggtgagcag gagcagcggg gcactcagcg aggggacgtc      720

ctgcctaatg ctgacgagac atggtatctc cgagcaaccc tggatgtggc ggctggggag      780

gcagctggcc tgtcctgtcg ggtgaaacac agcagtctag ggggccatga tctaatcatc      840

cattggggtg gatat                                                       855


<210>  3248
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  3248
aaagagatta cgaatgcctt ggaaacctgg ggtgccttgg gtcaggacat caacttggac       60

attcctagtt ttcaaatgag tgatgatatt gacgatataa aatgggaaaa aacttcagac      120

aagaaaaaga ttgcacaatt cagaaaagag aaagagactt tcaaggaaaa agatacatat      180

aagctattta aaaatggaac tctgaaaatt aagcatctga agaccgatga tcaggatatc      240

tacaaggtat caatatatga tacaaaagga aaaaatgtgt tggaaaaaat atttgatttg      300

aagattcaag agagggtctc aaaaccaaag atctcctgga cttgtatcaa cacaaccctg      360

acctgtgagg taatgaatgg aactgacccc gaattaaacc tgtatcaaga tgggaaacat      420

ctaaaacttt ctcagagggt catcacacac aagtggacca ccagcctgag tgcaaaattc      480

aagtgcacag cagggaacaa agtcagcaag gaatccagtg tcgagcctgt cagctgtcca      540

gagaaaggtc tggac                                                       555


<210>  3249
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  3249
caagtgcaag tggtgaccca ggatgaaaga gagcagctgt acacacctgc ttccttaaaa       60

tgctctctgc aaaatgccca ggaagccctc attgtgacat ggcagaaaaa gaaagctgta      120

agcccagaaa acatggtcac cttcagcgag aaccatgggg tggtgatcca gcctgcctat      180

aaggacaaga taaacattac ccagctggga ctccaaaact caaccatcac cttctggaat      240

atcaccctgg aggatgaagg gtgttacatg tgtctcttca atacctttgg ttttgggaag      300

atctcaggaa cggcctgcct caccgtctat gtacagccca tagtatccct tcactacaaa      360

ttctctgaag accacctaaa tatcacttgc tctgccactg cccgcccagc ccccatggtc      420

ttctggaagg tccctcggtc agggattgaa aatagtacag tgactctgtc tcacccaaat      480

gggaccacgt ctgttaccag catcctccat atcaaagacc ctaagaatca ggtggggaag      540

gaggtgatct gccaggtgct gcacctgggg actgtgaccg actttaagca aaccgtcaac      600

aaaggc                                                                 606


<210>  3250
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  3250
atggatgaaa aacagattac acagaactac tcgaaagtac tcgcagaagt taacacttca       60

tggcctgtaa agatggctac aaatgctgtg ctttgttgcc ctcctatcgc attaagaaat      120

ttgatcataa taacatggga aataatcctg agaggccagc cttcctgcac aaaagcctac      180

aagaaagaaa caaatgagac caaggaaacc aactgtactg atgagagaat aacctgggtc      240

tccagacctg atcagaattc ggaccttcag attcgtaccg tggccatcac tcatgacggg      300

tattacagat gcataatggt aacacctgat gggaatttcc atcgtggata tcacctccaa      360

gtgttagtta cacctgaagt gaccctgttt caaaacagga atagaactgc agtatgcaag      420

gcagttgcag ggaagccagc tgcgcatatc tcctggatcc cagagggcga ttgtgccact      480

aagcaagaat actggagcaa tggcacagtg actgttaaga gtacatgcca ctgggaggtc      540

cacaatgtgt ctaccgtgac ctgccacgtc tcccatttga ctggcaacaa gagtctgtac      600

atagagctac ttcctgttcc aggtgccaaa aaatcagcaa aatta                      645


<210>  3251
<211>  261
<212>  DNA
<213>  Homo Sapiens

<400>  3251
atggatataa atgctgtgct ttgttgccct cctatcgcat taagaaatct gatcataata       60

acatgggaaa taatcctgag aggccagcct tcctgcacaa aagcctacaa gaaagaaaca      120

aatgagacca aggaaaccaa ctgtactgtt gagagaataa cctgggtctc tagacctgat      180

cagaattcgg accttcagat tcgtccggtg gacaccactc atgacgggta ttacagaggc      240

atagtggtaa cacctgatgg g                                                261


<210>  3252
<211>  792
<212>  DNA
<213>  Homo Sapiens

<400>  3252
ccccggttta tgggcaccat atcagatgta aagaccaatg tccagttgct gaaaggtcgt       60

gtggacaaca tcagcaccct ggattctgaa attaaaaaga atagtgacgg catggaggca      120

gctggcgttc agatccagat ggtgaatgag agcctgggtt atgtgcgttc tcagttcctg      180

aagttaaaaa ccagtgtgga gaaggccaac gcacagatcc agatcttaac aagaagttgg      240

gaagaagtca gtaccttaaa tgcccaaatc ccagagttaa aaagtgattt ggagaaagcc      300

agtgctttaa atacaaagat ccgggcactc cagggcagct tggagaatat gagcaagttg      360

ctcaaacgac aaaatgatat tctacaggtg gtttctcaag gctggaagta cttcaagggg      420

aacttctatt acttttctct cattccaaag acctggtata gtgccgagca gttctgtgtg      480

tccaggaatt cacacctgac ctcggtgacc tcagagagtg agcaggagtt tctgtataaa      540

acagcggggg gactcatcta ctggattggc ctgactaaag cagggatgga aggggactgg      600

tcctgggtgg atgacacgcc attcaacaag gtccaaagtg cgaggttctg gattccaggt      660

gagcccaaca atgctgggaa caatgaacac tgtggcaata taaaggctcc ctcacttcag      720

gcctggaatg atgccccatg tgacaaaacg tttcttttca tttgtaagcg accctatgtc      780

ccatcagaac cg                                                          792


<210>  3253
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  3253
gcagtgtcca aggtccccag ctccataagt caggaacaat ccaggcaaga cgcgatctac       60

cagaacctga cccagcttaa agctgcagtg ggtgagctct cagagaaatc caagctgcag      120

gagatctacc aggagctgac ccagctgaag gctgcagtgg gtgagcttcc agagaaatct      180

aagctgcagg agatctacca ggagctgacc cggctgaagg ctgcagtggg tgagcttcca      240

gagaaatcta agctgcagga gatctaccag gagctgacct ggctgaaggc tgcagtgggt      300

gagcttccag agaaatctaa gatgcaggag atctaccagg agctgactcg gctgaaggct      360

gcagtgggtg agcttccaga gaaatctaag cagcaggaga tctaccagga gctgacccgg      420

ctgaaggctg cagtgggtga gcttccagag aaatctaagc agcaggagat ctaccaggag      480

ctgacccggc tgaaggctgc agtgggtgag cttccagaga aatctaagca gcaggagatc      540

taccaggagc tgacccagct gaaggctgca gtggaacgcc tgtgccaccc ctgtccctgg      600

gaatggacat tcttccaagg aaactgttac ttcatgtcta actcccagcg gaactggcac      660

gactccatca ccgcctgcaa agaagtgggg gcccagctcg tcgtaatcaa aagtgctgag      720

gagcagaact tcctacagct gcagtcttcc agaagtaacc gcttcacctg gatgggactt      780

tcagatctaa atcaggaagg cacgtggcaa tgggtggacg gctcacctct gttgcccagc      840

ttcaagcagt attggaacag aggagagccc aacaacgttg gggaggaaga ctgcgcggaa      900

tttagtggca atggctggaa cgacgacaaa tgtaatcttg ccaaattctg gatctgcaaa      960

aagtccgcag cctcctgctc cagggatgaa gaacagtttc tttctccagc ccctgccacc     1020

ccaaacccc                                                             1029


<210>  3254
<211>  1545
<212>  DNA
<213>  Homo Sapiens

<400>  3254
atgtctctgt ggctcctaga gggggttcca atgaggcagg ctgctgtcac ctcgacctcc       60

ttgaccatca agtctgtctt cacccggagc gagctcaagt tctccccaca gtggagtcac      120

catgggaaga ttgtgacctg ccagcttcag gatgcagatg ggaagttcct ctccaatgac      180

acggtgcagc tgaacgtgaa gcacaccccg aagttggaga tcaaggtcac tcccagtgat      240

gccatagtga gggaggggga ctctgtgacc atgacctgcg aggtcagcag cagcaacccg      300

gagtacacga cggtatcctg gctcaaggat gggacctcgc tgaagaagca gaatacattc      360

acgctaaacc tgcgcgaagt gaccaaggac cagagtggga agtactgctg tcaggtctcc      420

aatgacgtgg gcccgggaag gtcggaagaa gtgttcctgc aagtgcagta tgccccggaa      480

ccttccacgg ttcagatcct ccactcaccg gctgtggagg gaagtcaagt cgagtttctt      540

tgcatgtcac tggccaatcc tcttccaaca aattacacgt ggtaccacaa tgggaaagaa      600

atgcagggaa ggacagagga gaaagtccac atcccaaaga tcctcccctg gcacgctggg      660

acttattcct gtgtggcaga aaacattctt ggtactggac agaggggccc gggagctgag      720

ctggatgtcc agtatcctcc caagaaggtg accacagtga ttcaaaaccc catgccgatt      780

cgagaaggag acacagtgac cctttcctgt aactacaatt ccagtaaccc cagtgttacc      840

cggtatgaat ggaaacccca tggcgcctgg gaggagccat cgcttggggt gctgaagatc      900

caaaacgttg gctgggacaa cacaaccatc gcctgcgcag cttgtaatag ttggtgctcg      960

tgggcctccc ctgtcgccct gaatgtccag tatgcccccc gagacgtgag ggtccggaaa     1020

atcaagcccc tttccgagat tcactctgga aactcggtca gcctccaatg tgacttctca     1080

agcagccacc ccaaagaagt ccagttcttc tgggagaaaa atggcaggct tctggggaaa     1140

gaaagccagc tgaattttga ctccatctcc ccagaagatg ctgggagtta cagctgctgg     1200

gtgaacaact ccataggaca gacagcgtcc aaggcctgga cacttgaagt gctgtatgca     1260

cccaggaggc tgcgtgtgtc catgagcccg ggggaccaag tgatggaggg gaagagtgca     1320

accctgacct gtgagagcga cgccaaccct cccgtctccc actacacctg gtttgactgg     1380

aataaccaaa gcctccccta ccacagccag aagctgagat tggagccggt gaaggtccag     1440

cactcgggtg cctactggtg ccaggggacc aacagtgtgg gcaagggccg ttcgcctctc     1500

agcaccctca ccgtctacta tagcccggag accatcggca ggcga                     1545


<210>  3255
<211>  708
<212>  DNA
<213>  Homo Sapiens

<400>  3255
gaagaggtgc tttggcatac atcagttccc tttgccgaga acatgtctct agaatgtgtg       60

tatccatcaa tgggcatctt aacacaggtg gagtggttca agatcgggac ccagcaggat      120

tccatagcca ttttcagccc tactcatggc atggtcataa ggaagcccta tgctgagagg      180

gtttactttt tgaattcaac gatggcttcc aataacatga ctcttttctt tcggaatgcc      240

tctgaagatg atgttggcta ctattcctgc tctctttaca cttacccaca gggaacttgg      300

cagaaggtga tacaggtggt tcagtcagat agttttgagg cagctgtgcc atcaaatagc      360

cacattgttt cggaacctgg aaagaatgtc acactcactt gtcagcctca gatgacgtgg      420

cctgtgcagg cagtgaggtg ggaaaagatc cagccccgtc agatcgacct cttaacttac      480

tgcaacttgg tccatggcag aaatttcacc tccaagttcc caagacaaat agtgagcaac      540

tgcagccacg gaaggtggag cgtcatcgtc atccccgatg tcacagtctc agactcgggg      600

ctttaccgct gctacttgca ggccagcgca ggagaaaacg aaaccttcgt gatgagattg      660

actgtagccg agggtaaaac cgataaccaa tataccctct ttgtggct                   708


<210>  3256
<211>  609
<212>  DNA
<213>  Homo Sapiens

<400>  3256
tgccagggat cagctgacca tgtggttagc atctcgggag tgcctcttca gttacaacca       60

aacagcatac agacgaaggt tgacagcatt gcatggaaga agttgctgcc ctcacaaaat      120

ggatttcatc acatattgaa gtgggagaat ggctctttgc cttccaatac ttccaatgat      180

agattcagtt ttatagtcaa gaacttgagt cttctcatca aggcagctca gcagcaggac      240

agtggcctct actgcctgga ggtcaccagt atatctggaa aagttcagac agccacgttc      300

caggtttttg tatttgataa agttgagaaa ccccgcctac aggggcaggg gaagatcctg      360

gacagaggga gatgccaagt ggctctgtct tgcttggtct ccagggatgg caatgtgtcc      420

tatgcttggt acagagggag caagctgatc cagacagcag ggaacctcac ctacctggac      480

gaggaggttg acattaatgg cactcacaca tatacctgca atgtcagcaa tcctgttagc      540

tgggaaagcc acaccctgaa tctcactcag gactgtcaga atgcccatca ggaattcaga      600

ttttggccg                                                              609


<210>  3257
<211>  2010
<212>  DNA
<213>  Homo Sapiens

<400>  3257
caggacccct gggctgctga gccccgtgcc gcctgcggcc ccagcagctg ctacgctctc       60

ttcccacggc gccgcacctt cctggaggcc tggcgggcct gccgcgagct ggggggcgac      120

ctggccactc ctcggacccc cgaggaggcc cagcgtgtgg acagcctggt gggtgcgggc      180

ccagccagcc ggctgctgtg gatcgggctg cagcggcagg cccggcaatg ccagctgcag      240

cgcccactgc gcggcttcac gtggaccaca ggggaccagg acacggcttt caccaactgg      300

gcccagccag cctctggagg cccctgcccg gcccagcgct gtgtggccct ggaggcaagt      360

ggcgagcacc gctggctgga gggctcgtgc acgctggctg tcgacggcta cctgtgccag      420

tttggcttcg agggcgcctg cccggcgctg caagatgagg cgggccaggc cggcccagcc      480

gtgtatacca cgcccttcca cctggtctcc acagagtttg agtggctgcc cttcggctct      540

gtggccgctg tgcagtgcca ggctggcagg ggagcctctc tgctctgcgt gaagcagcct      600

gagggaggtg tgggctggtc acgggctggg cccctgtgcc tggggactgg ctgcagccct      660

gacaacgggg gctgcgaaca cgaatgtgtg gaggaggtgg atggtcacgt gtcctgccgc      720

tgcactgagg gcttccggct ggcagcagac gggcgcagtt gcgaggaccc ctgtgcccag      780

gctccgtgcg agcagcagtg tgagcccggt gggccacaag gctacagctg ccactgtcgc      840

ctgggtttcc ggccagcgga ggatgatccg caccgctgtg tggacacaga tgagtgccag      900

attgccggtg tgtgccagca gatgtgtgtc aactacgttg gtggcttcga gtgttattgt      960

agcgagggac atgagctgga ggctgatggc atcagctgca gccctgcagg ggccatgggt     1020

gcccaggctt cccaggacct cggagatgag ttgctggatg acggggagga tgaggaagat     1080

gaagacgagg cctggaaggc cttcaacggt ggctggacgg agatgcctgg gatcctgtgg     1140

atggagccta cgcagccgcc tgactttgcc ctggcctata gaccgagctt cccagaggac     1200

agagagccac agatacccta cccggagccc acctggccac ccccgctcag tgcccccagg     1260

gtcccctacc actcctcagt gctctccgtc acccggcctg tggtggtctc tgccacgcat     1320

cccacactgc cttctgccca ccagcctcct gtgatccctg ccacacaccc agctttgtcc     1380

cgtgaccacc agatccccgt gatcgcagcc aactatccag atctgccttc tgcctaccaa     1440

cccggtattc tctctgtctc tcattcagca cagcctcctg cccaccagcc ccctatgatc     1500

tcaaccaaat atccggagct cttccctgcc caccagtccc ccatgtttcc agacacccgg     1560

gtcgctggca cccagaccac cactcatttg cctggaatcc cacctaacca tgcccctctg     1620

gtcaccaccc tcggtgccca gctaccccct caagccccag atgcccttgt cctcagaacc     1680

caggccaccc agcttcccat tatcccaact gcccagccct ctctgaccac cacctccagg     1740

tcccctgtgt ctcctgccca tcaaatctct gtgcctgctg ccacccagcc cgcagccctc     1800

cccaccctcc tgccctctca gagccccact aaccagacct cacccatcag ccctacacat     1860

ccccattcca aagcccccca aatcccaagg gaagatggcc ccagtcccaa gttggccctg     1920

tggctgccct caccagctcc cacagcagcc ccaacagccc tgggggaggc tggtcttgcc     1980

gagcacagcc agagggatga ccggtggctg                                      2010


<210>  3258
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  3258
tttactgtca cggttcccaa ggacctatat gtggtagagt atggtagcaa tatgacaatt       60

gaatgcaaat tcccagtaga aaaacaatta gacctggctg cactaattgt ctattgggaa      120

atggaggata agaacattat tcaatttgtg catggagagg aagacctgaa ggttcagcat      180

agtagctaca gacagagggc ccggctgttg aaggaccagc tctccctggg aaatgctgca      240

cttcagatca cagatgtgaa attgcaggat gcaggggtgt accgctgcat gatcagctat      300

ggtggtgccg actacaagcg aattactgtg aaagtcaatg ccccatacaa caaaatcaac      360

caaagaattt tggttgtgga tccagtcacc tctgaacatg aactgacatg tcaggctgag      420

ggctacccca aggccgaagt catctggaca agcagtgacc atcaagtcct gagtggtaag      480

accaccacca ccaattccaa gagagaggag aagcttttca atgtgaccag cacactgaga      540

atcaacacaa caactaatga gattttctac tgcactttta ggagattaga tcctgaggaa      600

aaccatacag ctgaattggt catcccagaa ctacctctgg cacatcctcc aaatgaaagg      660


<210>  3259
<211>  1284
<212>  DNA
<213>  Homo Sapiens

<400>  3259
ctggaggtcc aggtccctga agacccagtg gtggcactgg tgggcaccga tgccaccctg       60

tgctgctcct tctcccctga gcctggcttc agcctggcac agctcaacct catctggcag      120

ctgacagata ccaaacagct ggtgcacagc tttgctgagg gccaggacca gggcagcgcc      180

tatgccaacc gcacggccct cttcccggac ctgctggcac agggcaacgc atccctgagg      240

ctgcagcgcg tgcgtgtggc ggacgagggc agcttcacct gcttcgtgag catccgggat      300

ttcggcagcg ctgccgtcag cctgcaggtg gccgctccct actcgaagcc cagcatgacc      360

ctggagccca acaaggacct gcggccaggg gacacggtga ccatcacgtg ctccagctac      420

cagggctacc ctgaggctga ggtgttctgg caggatgggc agggtgtgcc cctgactggc      480

aacgtgacca cgtcgcagat ggccaacgag cagggcttgt ttgatgtgca cagcatcctg      540

cgggtggtgc tgggtgcaaa tggcacctac agctgcctgg tgcgcaaccc cgtgctgcag      600

caggatgcgc acagctctgt caccatcaca ccccagagaa gccccacagg agccgtggag      660

gtccaggtcc ctgaggaccc ggtggtggcc ctagtgggca ccgatgccac cctgcgctgc      720

tccttctccc ccgagcctgg cttcagcctg gcacagctca acctcatctg gcagctgaca      780

gacaccaaac agctggtgca cagtttcacc gaaggccggg accagggcag cgcctatgcc      840

aaccgcacgg ccctcttccc ggacctgctg gcacaaggca atgcatccct gaggctgcag      900

cgcgtgcgtg tggcggacga gggcagcttc acctgcttcg tgagcatccg ggatttcggc      960

agcgctgccg tcagcctgca ggtggccgct ccctactcga agcccagcat gaccctggag     1020

cccaacaagg acctgcggcc aggggacacg gtgaccatca cgtgctccag ctaccggggc     1080

taccctgagg ctgaggtgtt ctggcaggat gggcagggtg tgcccctgac tggcaacgtg     1140

accacgtcgc agatggccaa cgagcagggc ttgtttgatg tgcacagcgt cctgcgggtg     1200

gtgctgggtg cgaatggcac ctacagctgc ctggtgcgca accccgtgct gcagcaggat     1260

gcgcacggct ctgtcaccat caca                                            1284


<210>  3260
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  3260
aacaagattt tggtgaagca gtcgcccatg cttgtagcgt acgacaatgc ggtcaacctt       60

agctgcaagt attcctacaa tctcttctca agggagttcc gggcatccct tcacaaagga      120

ctggatagtg ctgtggaagt ctgtgttgta tatgggaatt actcccagca gcttcaggtt      180

tactcaaaaa cggggttcaa ctgtgatggg aaattgggca atgaatcagt gacattctac      240

ctccagaatt tgtatgttaa ccaaacagat atttacttct gcaaaattga agttatgtat      300

cctcctcctt acctagacaa tgagaagagc aatggaacca ttatccatgt gaaagggaaa      360

cacctttgtc caagtcccct atttcccgga ccttctaagc cc                         402


<210>  3261
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  3261
ctgagcaaat gcaggaccgt ggcgggcccc gtggggggat ccctgagtgt gcagtgtccc       60

tatgagaagg aacacaggac cctcaacaaa tactggtgca gaccaccaca gattttccta      120

tgtgacaaga ttgtggagac caaagggtca gcaggaaaaa ggaacggccg agtgtccatc      180

agggacagtc ctgcaaacct cagcttcaca gtgaccctgg agaatctcac agaggaggat      240

gcaggcacct actggtgtgg ggtggataca ccatggctcc gagactttca tgatcccgtt      300

gtcgaggttg aggtgtccgt gttcccggca tcaacgtcaa tgacacctgc aagtatcact      360

gcggccaaga cctcaacaat cacaactgca tttccacctg tatcatccac taccctgttt      420

gcagtgggtg ccacccacag tgccagcatc caggaggaaa ctgaggaggt ggtgaactca      480

cagctcccg                                                              489


<210>  3262
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  3262
ggctattttc ctctgagcca ccccatgacc gtggcgggcc ccgtgggggg atccctgagt       60

gtgcagtgtc gctatgagaa ggaacacagg accctcaaca aattctggtg cagaccacca      120

cagattctcc gatgtgacaa gattgtggag accaaagggt cagcagggaa aaggaatggc      180

cgagtgtcca tcagggacag tcctgcaaac ctcagcttca cagtgaccct ggagaatctc      240

acagaggagg acgcaggcac ctactggtgt ggggtggata caccgtggct ccgagacttt      300

catgatccca ttgtcgaggt tgaggtgtcc gtgttcccgg ccgggacgac cacagcctcc      360

agcccccaga gctccatggg cacctcaggt cctcccacga agctgcccgt gcacacctgg      420

cccagcgtga ccagaaagga cagccccgaa cccagcccac accctggctc cctgttcagc      480

aatgtccgc                                                              489


<210>  3263
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  3263
ctgaagggcc ccggctctgt gactggcact gcgggggact ctctgacagt gtggtgtcag       60

tatgagagca tgtacaaggg atataacaag tactggtgcc gaggacagta cgacacgtca      120

tgtgagagca ttgtggagac caagggagaa gagaaggtgg agaggaatgg ccgcgtgtcc      180

atcagagacc acccggaggc tctcgccttc actgtgacca tgcagaacct caatgaagat      240

gatgctggat cttactggtg caaaattcag acagtgtggg tcctggattc atggtcacgc      300

gatccctcgg acctggttag ggtgtatgtt tccccagcaa ttacaacccc aaggaggacc      360

acacatccag ccacacctcc catcttcctg gtggtgaacc ctgggcgaaa cctcagcacc      420

agggaggtgt tgacccaaaa ttcagggttc cggctcagca gccctcac                   468


<210>  3264
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  3264
atccaaggcc cagagtctgt gagagcccca gagcaggggt ccctgacggt tcaatgccac       60

tataagcaag gatgggagac ctacattaag tggtggtgcc gaggggtgcg ctgggataca      120

tgcaagatcc tcattgaaac cagagggtcg gagcaaggag agaagagtga ccgtgtgtcc      180

atcaaggaca atcagaaaga ccgcacgttc actgtgacca tggaggggct caggcgagat      240

gacgcagatg tttactggtg tgggattgaa agaagaggac ctgaccttgg gactcaagtg      300

aaagtgatcg ttgacccaga gggagcggct tccacaacag caagctcacc taccaacagc      360

aatatggcag tgttcatcgg ctcccacaag aggaaccact ac                         402


<210>  3265
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  3265
gcaaaaatta caggtcctac gactgtcaac ggttccgagc agggctcttt aaccgtgcag       60

tgcgcttatg ggagtgggtg ggaaacatat ctaaagtggc gttgtcaggg ggcagattgg      120

aattattgta atatcctggt aaagactaat ggctccgagc aggaggtcaa aaaaaacaga      180

gtgtccatca gagataatca aaagaaccat gttttcaccg tcaccatgga gaacttgaag      240

agagatgatg cggactctta ctggtgtggg acagagaggc cgggcataga tttaggtgtt      300

aaggtacaag tgacaatcaa ccctggaacg caaacagctg tttctgagtg gacgacaact      360

accgccagcc tggcgttcac tgccgccgct acacagaaga cgagctcccc attaacccgt      420

tcacccctga aatcaacgca t                                                441


<210>  3266
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  3266
actcaaatca ccggtccaac aacagtgaat ggcttggagc ggggctcctt gaccgtgcag       60

tgtgtttaca gatcaggctg ggagacctac ttgaagtggt ggtgtcgagg agctatttgg      120

cgtgactgca agatccttgt taaaaccagt gggtcagagc aggaggtgaa gagggaccgg      180

gtgtccatca aggacaatca gaaaaaccgc acgttcactg tgaccatgga ggatctcatg      240

aaaactgatg ctgacactta ctggtgtgga attgagaaaa ctggaaatga ccttggggtc      300

acagttcaag tgaccattga cccagcacca gtcacccaag aagaaactag cagctcccca      360

actctgaccg gccaccactt ggacaacagc agccgggatg tccccagagc aggtactgca      420

gcccctggag ggcgacctct gctatgcaga cctgaccctg cagctggccg gaacctcccc      480

gcgaaaggct accacgaagc tttcctctgc ccaggt                                516


<210>  3267
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  3267
ctggagggcc cagaggaaat cagcgggttc gaaggggaca ctgtgtccct gcagtgcacc       60

tacagggaag agctgaggga ccaccggaag tactggtgca ggaagggtgg gatcctcttc      120

tctcgctgct ctggcaccat ctatgcagaa gaagaaggcc aggagacaat gaagggcagg      180

gtgtccatcc gtgacagccg ccaggagctc tcgctcattg tgaccctgtg gaacctcacc      240

ctgcaagacg ctggggagta ctggtgtggg gtcgaaaaac ggggccccga tgagtcttta      300

ctgatctctc tgttcgtctt tccaggaccc tgctgtcctc cctccccttc tcccaccttc      360

cagcctctgg ctacaacacg cctgcagccc aaggcaaaag ctcagcaaac ccagccccca      420

ggattgactt ctcctgggct ctacccggca gccaccacag ccaagcaggg gaagacaggg      480

gctgaggccc ctccattgcc agggacttcc cagtacgggc acgaaaggac ttctcagtac      540

acaggaacct ctcctcaccc agcgacctct cctcctgcag ggagctcccg cccccccatg      600

cagctgaact ccacctcagc agaggacacc agtccagctc tcagcagtgg cagctctaag      660

cccagggtgt ccatcccgat ggtccgc                                          687


<210>  3268
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  3268
ttccaggact cctgttacat ttttctccaa gaagccatca aagtagaaag catagaggat       60

gtcagaaatc agtgtactga ccatggagcg gacatgataa gcatacataa tgaagaagaa      120

aatgctttta tactggatac tttgaaaaag caatggaaag gcccagatga tatcctacta      180

ggcatgtttt atgacacaga tgatgcgagt ttcaagtggt ttgataattc aaatatgaca      240

tttgataagt ggacagacca agatgatgat gaggatttag ttgacacctg tgcttttctg      300

cacatcaaga caggtgaatg gaaaaaagga aattgtgaag tttcttctgt ggaaggaaca      360

ctatgcaaaa cagctatccc atacaaaagg aaatatttat cagataacca c               411


<210>  3269
<211>  582
<212>  DNA
<213>  Homo Sapiens

<400>  3269
agcccgcttt ccaccccgac ctctgcccag gccgcaggcc ccagctcagg ctcgtgccca       60

cccaccaagt tccagtgccg caccagtggc ttatgcgtgc ccctcacctg gcgctgcgac      120

agggacttgg actgcagcga tggcagcgat gaggaggagt gcaggattga gccatgtacc      180

cagaaagggc aatgcccacc gccccctggc ctcccctgcc cctgcaccgg cgtcagtgac      240

tgctctgggg gaactgacaa gaaactgcgc aactgcagcc gcctggcctg cctagcaggc      300

gagctccgtt gcacgctgag cgatgactgc attccactca cgtggcgctg cgacggccac      360

ccagactgtc ccgactccag cgacgagctc ggctgtggaa ccaatgagat cctcccggaa      420

ggggatgcca caaccatggg gccccctgtg accctggaga gtgtcacctc tctcaggaat      480

gccacaacca tggggccccc tgtgaccctg gagagtgtcc cctctgtcgg gaatgccaca      540

tcctcctctg ccggagacca gtctggaagc ccaactgcct at                         582


<210>  3270
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  3270
gatccaaatt tctggctgca agtgcaggag tcagtgacgg tacaggaggg tttgtgcgtc       60

ctcgtgccct gcactttctt ccatcccata ccctactacg acaagaactc cccagttcat      120

ggttactggt tccgggaagg agccattata tccggggact ctccagtggc cacaaacaag      180

ctagatcaag aagtacagga ggagactcag ggcagattcc gcctccttgg ggatcccagt      240

aggaacaact gctccctgag catcgtagac gccaggagga gggataatgg ttcatacttc      300

tttcggatgg agagaggaag taccaaatac agttacaaat ctccccagct ctctgtgcat      360

gtgacagact tgacccacag gcccaaaatc ctcatccctg gcactctaga acccggccac      420

tccaaaaacc tgacctgctc tgtgtcctgg gcctgtgagc agggaacacc cccgatcttc      480

tcctggttgt cagctgcccc cacctccctg ggccccagga ctactcactc ctcggtgctc      540

ataatcaccc cacggcccca ggaccacggc accaacctga cctgtcaggt gaagttcgct      600

ggagctggtg tgactacgga gagaaccatc cagctcaacg tcacctatgt tccacagaac      660

ccaacaactg gtatctttcc aggagatggc tcagggaaac aagagaccag agcaggagtg      720

gttcat                                                                 726


<210>  3271
<211>  777
<212>  DNA
<213>  Homo Sapiens

<400>  3271
agtcttgaca acaacggtac tgctacccca gagttaccta cccagggaac attttcaaat       60

gtttctacaa atgtatccta ccaagaaact acaacaccta gtacccttgg aagtaccagc      120

ctgcaccctg tgtctcaaca tggcaatgag gccacaacaa acatcacaga aacgacagtc      180

aaattcacat ctacctctgt gataacctca gtttatggaa acacaaactc ttctgtccag      240

tcacagacct ctgtaatcag cacagtgttc accaccccag ccaacgtttc aactccagag      300

acaaccttga agcctagcct gtcacctgga aatgtttcag acctttcaac cactagcact      360

agccttgcaa catctcccac taaaccctat acatcatctt ctcctatcct aagtgacatc      420

aaggcagaaa tcaaatgttc aggcatcaga gaagtgaaat tgactcaggg catctgcctg      480

gagcaaaata agacctccag ctgtgcggag tttaagaagg acaggggaga gggcctggcc      540

cgagtgctgt gtggggagga gcaggctgat gctgatgctg gggcccaggt atgctccctg      600

ctccttgccc agtctgaggt gaggcctcag tgtctactgc tggtcttggc caacagaaca      660

gaaatttcca gcaaactcca acttatgaaa aagcaccaat ctgacctgaa aaagctgggg      720

atcctagatt tcactgagca agatgttgca agccaccaga gctattccca aaagacc         777


<210>  3272
<211>  1215
<212>  DNA
<213>  Homo Sapiens

<400>  3272
cagaagacaa ttaaaaagca agttgtcctc gaagaaggta caattgcttt taaaaattgg       60

gttaaaacag gcacagaagt ttacagacag ttttggatct ttgatgtgca aaatccacag      120

gaagtgatga tgaacagcag caacattcaa gttaagcaaa gaggtcctta tacgtacaga      180

gttcgttttc tagccaagga aaatgtaacc caggacgctg aggacaacac agtctctttc      240

ctgcagccca atggtgccat cttcgaacct tcactatcag ttggaacaga ggctgacaac      300

ttcacagttc tcaatctggc tgtggcagct gcatcccata tctatcaaaa tcaatttgtt      360

caaatgatcc tcaattcact tattaacaag tcaaaatctt ctatgttcca agtcagaact      420

ttgagagaac tgttatgggg ctatagggat ccatttttga gtttggttcc ataccctgtt      480

actaccacag ttggtctgtt ttatccttac aacaatactg cagatggagt ttataaagtt      540

ttcaatggaa aagataacat aagtaaagtt gccataatcg acacatataa aggtaaaagg      600

aatctgtcct attgggaaag tcactgcgac atgattaatg gtacagatgc agcctcattt      660

ccaccttttg ttgagaaaag ccaggtattg cagttctttt cttctgatat ttgcaggtca      720

atctatgctg tatttgaatc cgacgttaat ctgaaaggaa tccctgtgta tagatttgtt      780

cttccatcca aggcctttgc ctctccagtt gaaaacccag acaactattg tttctgcaca      840

gaaaaaatta tctcaaaaaa ttgtacatca tatggtgtgc tagacatcag caaatgcaaa      900

gaagggagac ctgtgtacat ttcacttcct cattttctgt atgcaagtcc tgatgtttca      960

gaacctattg atggattaaa cccaaatgaa gaagaacata ggacatactt ggatattgaa     1020

cctataactg gattcacttt acaatttgca aaacggctgc aggtcaacct attggtcaag     1080

ccatcagaaa aaattcaagt attaaagaat ctgaagagga actatattgt gcctattctt     1140

tggcttaatg agactgggac cattggtgat gagaaggcaa acatgttcag aagtcaagta     1200

actggaaaaa taaac                                                      1215


<210>  3273
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  3273
cgggcccagc tggagcgaag cttgcgggac gtcgtagaga aaaccatcca aaagtacggc       60

accaaccccg aggagaccgc ggccgaggag agctgggact atgtgcagtt ccagctgcgc      120

tgctgcggct ggcactaccc gcaggactgg ttccaagtcc tcatcctgag aggtaacggg      180

tcggaggcgc accgcgtgcc ctgctcctgc tacaacttgt cggcgaccaa cgactccaca      240

atcctagata aggtgatctt gccccagctc agcaggcttg gacacctggc gcggtccaga      300

cacagtgcag acatctgcgc tgtccctgca gagagccaca tctaccgcga gggctgcgcg      360

cagggcctcc agaagtggct gcacaacaac                                       390


<210>  3274
<211>  774
<212>  DNA
<213>  Homo Sapiens

<400>  3274
gtcccgaggt ggcgccagca gtggagcggt ccgggcacca ccaagcgctt tcccgagacc       60

gtcctggcgc gatgcgtcaa gtacactgaa attcatcctg agatgagaca tgtagactgc      120

caaagtgtat gggatgcttt caagggtgca tttatttcaa aacatccttg caacattact      180

gaagaagact atcagccact aatgaagttg ggaactcaga ccgtaccttg caacaagatt      240

cttctttgga gcagaataaa agatctggcc catcagttca cacaggtcca gcgggacatg      300

ttcaccctgg aggacacgct gctaggctac cttgctgatg acctcacatg gtgtggtgaa      360

ttcaacactt ccaaaataaa ctatcaatct tgcccagact ggagaaagga ctgcagcaac      420

aaccctgttt cagtattctg gaaaacggtt tcccgcaggt ttgcagaagc tgcctgtgat      480

gtggtccatg tgatgctcaa tggatcccgc agtaaaatct ttgacaaaaa cagcactttt      540

gggagtgtgg aagtccataa tttgcaacca gagaaggttc agacactaga ggcctgggtg      600

atacatggtg gaagagaaga ttccagagac ttatgccagg atcccaccat aaaagagctg      660

gaatcgatta taagcaaaag gaatattcaa ttttcctgca agaatatcta cagacctgac      720

aagtttcttc agtgtgtgaa aaatcctgag gattcatctt gcacatctga gatc            774


<210>  3275
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  3275
ttcaagatac ctatagagga acttgaggac agagtgtttg tgaattgcaa taccagcatc       60

acatgggtag agggaacggt gggaacactg ctctcagaca ttacaagact ggacctggga      120

aaacgcatcc tggacccacg aggaatatat aggtgtaatg ggacagatat atacaaggac      180

aaagaatcta ccgtgcaagt tcattatcga atgtgccaga gctgtgtgga gctggatcca      240

gccaccgtgg ct                                                          252


<210>  3276
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  3276
gatggtaatg aagaaatggg tggtattaca cagacaccat ataaagtctc catctctgga       60

accacagtaa tattgacatg ccctcagtat cctggatctg aaatactatg gcaacacaat      120

gataaaaaca taggcggtga tgaggatgat aaaaacatag gcagtgatga ggatcacctg      180

tcactgaagg aattttcaga attggagcaa agtggttatt atgtctgcta ccccagagga      240

agcaaaccag aagatgcgaa cttttatctc tacctgaggg caagagtgtg tgagaactgc      300

atggagatgg at                                                          312


<210>  3277
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  3277
cagtcaatca aaggaaacca cttggttaag gtgtatgact atcaagaaga tggttcggta       60

cttctgactt gtgatgcaga agccaaaaat atcacatggt ttaaagatgg gaagatgatc      120

ggcttcctaa ctgaagataa aaaaaaatgg aatctgggaa gtaatgccaa ggaccctcga      180

gggatgtatc agtgtaaagg atcacagaac aagtcaaaac cactccaagt gtattacaga      240

atgtgtcaga actgcattga actaaatgca gccaccatat ct                         282


<210>  3278
<211>  1113
<212>  DNA
<213>  Homo Sapiens

<400>  3278
aagaaagtgg tgctgggcaa aaaaggggat acagtggaac tgacctgtac agcttcccag       60

aagaagagca tacaattcca ctggaaaaac tccaaccaga taaagattct gggaaatcag      120

ggctccttct taactaaagg tccatccaag ctgaatgatc gcgctgactc aagaagaagc      180

ctttgggacc aaggaaactt tcccctgatc atcaagaatc ttaagataga agactcagat      240

acttacatct gtgaagtgga ggaccagaag gaggaggtgc aattgctagt gttcggattg      300

actgccaact ctgacaccca cctgcttcag gggcagagcc tgaccctgac cttggagagc      360

ccccctggta gtagcccctc agtgcaatgt aggagtccaa ggggtaaaaa catacagggg      420

gggaagaccc tctccgtgtc tcagctggag ctccaggata gtggcacctg gacatgcact      480

gtcttgcaga accagaagaa ggtggagttc aaaatagaca tcgtggtgct agctttccag      540

aaggcctcca gcatagtcta taagaaagag ggggaacagg tggagttctc cttcccactc      600

gcctttacag ttgaaaagct gacgggcagt ggcgagctgt ggtggcaggc ggagagggct      660

tcctcctcca agtcttggat cacctttgac ctgaagaaca aggaagtgtc tgtaaaacgg      720

gttacccagg accctaagct ccagatgggc aagaagctcc cgctccacct caccctgccc      780

caggccttgc ctcagtatgc tggctctgga aacctcaccc tggcccttga agcgaaaaca      840

ggaaagttgc atcaggaagt gaacctggtg gtgatgagag ccactcagct ccagaaaaat      900

ttgacctgtg aggtgtgggg acccacctcc cctaagctga tgctgagctt gaaactggag      960

aacaaggagg caaaggtctc gaagcgggag aaggcggtgt gggtgctgaa ccctgaggcg     1020

gggatgtggc agtgtctgct gagtgactcg ggacaggtcc tgctggaatc caacatcaag     1080

gttctgccca catggtccac cccggtgcag cca                                  1113


<210>  3279
<211>  447
<212>  DNA
<213>  Homo Sapiens

<400>  3279
atgcaaaaag gtgatcagaa tcctcaaatt gcggcacatg tcataagtga ggccagcagt       60

aaaacaacat ctgtgttaca gtgggctgaa aaaggatact acaccatgag caacaacttg      120

gtaaccctgg aaaatgggaa acagctgacc gttaaaagac aaggactcta ttatatctat      180

gcccaagtca ccttctgttc caatcgggaa gcttcgagtc aagctccatt tatagccagc      240

ctctgcctaa agtcccccgg tagattcgag agaatcttac tcagagctgc aaatacccac      300

agttccgcca aaccttgcgg gcaacaatcc attcacttgg gaggagtatt tgaattgcaa      360

ccaggtgctt cggtgtttgt caatgtgact gatccaagcc aagtgagcca tggcactggc      420

ttcacgtcct ttggcttact caaactc                                          447


<210>  3280
<211>  1758
<212>  DNA
<213>  Homo Sapiens

<400>  3280
cagatcgatt tgaatataac ctgccgcttt gcaggtgtat tccacgtgga gaaaaatggt       60

cgctacagca tctctcggac ggaggccgct gacctctgca aggctttcaa tagcaccttg      120

cccacaatgg cccagatgga gaaagctctg agcatcggat ttgagacctg caggtatggg      180

ttcatagaag ggcatgtggt gattccccgg atccacccca actccatctg tgcagcaaac      240

aacacagggg tgtacatcct cacatccaac acctcccagt atgacacata ttgcttcaat      300

gcttcagctc cacctgaaga agattgtaca tcagtcacag acctgcccaa tgcctttgat      360

ggaccaatta ccataactat tgttaaccgt gatggcaccc gctatgtcca gaaaggagaa      420

tacagaacga atcctgaaga catctacccc agcaacccta ctgatgatga cgtgagcagc      480

ggctcctcca gtgaaaggag cagcacttca ggaggttaca tcttttacac cttttctact      540

gtacacccca tcccagacga agacagtccc tggatcaccg acagcacaga cagaatccct      600

gctaccagta cgtcttcaaa taccatctca gcaggctggg agccaaatga agaaaatgaa      660

gatgaaagag acagacacct cagtttttct ggatcaggca ttgatgatga tgaagatttt      720

atctccagca ccatttcaac cacaccacgg gcttttgacc acacaaaaca gaaccaggac      780

tggacccagt ggaacccaag ccattcaaat ccggaagtgc tacttcagac aaccacaagg      840

atgactgatg tagacagaaa tggcaccact gcttatgaag gaaactggaa cccagaagca      900

caccctcccc tcattcacca tgagcatcat gaggaagaag agaccccaca ttctacaagc      960

acaatccagg caactcctag tagtacaacg gaagaaacag ctacccagaa ggaacagtgg     1020

tttggcaaca gatggcatga gggatatcgc caaacaccca gagaagactc ccattcgaca     1080

acagggacag ctgcagcctc agctcatacc agccatccaa tgcaaggaag gacaacacca     1140

agcccagagg acagttcctg gactgatttc ttcaacccaa tctcacaccc catgggacga     1200

ggtcatcaag caggaagaag gatggatatg gactccagtc atagtacaac gcttcagcct     1260

actgcaaatc caaacacagg tttggtggaa gatttggaca ggacaggacc tctttcaatg     1320

acaacgcagc agagtaattc tcagagcttc tctacatcac atgaaggctt ggaagaagat     1380

aaagaccatc caacaacttc tactctgaca tcaagcaata ggaatgatgt cacaggtgga     1440

agaagagacc caaatcattc tgaaggctca actactttac tggaaggtta tacctctcat     1500

tacccacaca cgaaggaaag caggaccttc atcccagtga cctcagctaa gactgggtcc     1560

tttggagtta ctgcagttac tgttggagat tccaactcta atgtcaatcg ttccttatca     1620

ggagaccaag acacattcca ccccagtggg gggtcccata ccactcatgg atctgaatca     1680

gatggacact cacatgggag tcaagaaggt ggagcaaaca caacctctgg tcctataagg     1740

acaccccaaa ttccagaa                                                   1758


<210>  3281
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  3281
cagctactat ttaataaaac aaaatctgta gaattcacgt tttgtaatga cactgtcgtc       60

attccatgct ttgttactaa tatggaggca caaaacacta ctgaagtata cgtaaagtgg      120

aaatttaaag gaagagatat ttacaccttt gatggagctc taaacaagtc cactgtcccc      180

actgacttta gtagtgcaaa aattgaagtc tcacaattac taaaaggaga tgcctctttg      240

aagatggata agagtgatgc tgtctcacac acaggaaact acacttgtga agtaacagaa      300

ttaaccagag aaggtgaaac gatcatcgag ctaaaatatc gtgttgtttc atggttttct      360

ccaaatgaa                                                              369


<210>  3282
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  3282
atgtgctcca gaggttggga ttcgtgtctg gctctggaat tgctactgct gcctctgtca       60

ctcctggtga ccagcattca aggtcacttg gtacatatga ccgtggtctc cggcagcaac      120

gtgactctga acatctctga gagcctgcct gagaactaca aacaactaac ctggttttat      180

actttcgacc agaagattgt agaatgggat tccagaaaat ctaagtactt tgaatccaaa      240

tttaaaggca gggtcagact tgatcctcag agtggcgcac tgtacatctc taaggtccag      300

aaagaggaca acagcaccta catcatgagg gtgttgaaaa agactgggaa tgagcaagaa      360

tggaagatca agctgcaagt gcttggtgag tcaggggagc caaagagcaa atccccactc      420

cagtggcccc agatggacca ctgtagggct tcctgggagg catggggcac tctcggggag      480

gaggagagaa aaacctcagg acaggtt                                          507


<210>  3283
<211>  1044
<212>  DNA
<213>  Homo Sapiens

<400>  3283
cggctcagct ggtatgaccc agatttccag gcaaggctca cccgttccaa ctcgaagtgc       60

cagggccagc tggaggtcta cctcaaggac ggatggcaca tggtttgcag ccagagctgg      120

ggccggagct ccaagcagtg ggaggacccc agtcaagcgt caaaagtctg ccagcggctg      180

aactgtgggg tgcccttaag ccttggcccc ttccttgtca cctacacacc tcagagctca      240

atcatctgct acggacaact gggctccttc tccaactgca gccacagcag aaatgacatg      300

tgtcactctc tgggcctgac ctgcttagaa ccccagaaga caacacctcc aacgacaagg      360

cccccgccca ccacaactcc agagcccaca gctcctccca ggctgcagct ggtggcacag      420

tctggcggcc agcactgtgc cggcgtggtg gagttctaca gcggcagcct ggggggtacc      480

atcagctatg aggcccagga caagacccag gacctggaga acttcctctg caacaacctc      540

cagtgtggct ccttcttgaa gcatctgcca gagactgagg caggcagagc ccaagaccca      600

ggggagccac gggaacacca gcccttgcca atccaatgga agatccagaa ctcaagctgt      660

acctccctgg agcattgctt caggaaaatc aagccccaga aaagtggccg agttcttgcc      720

ctcctttgct caggtttcca gcccaaggtg cagagccgtc tggtgggggg cagcagcatc      780

tgtgaaggca ccgtggaggt gcgccagggg gctcagtggg cagccctgtg tgacagctct      840

tcagccagga gctcgctgcg gtgggaggag gtgtgccggg agcagcagtg tggcagcgtc      900

aactcctatc gagtgctgga cgctggtgac ccaacatccc gggggctctt ctgtccccat      960

cagaagctgt cccagtgcca cgaactttgg gagagaaatt cctactgcaa gaaggtgttt     1020

gtcacatgcc aggatccaaa cccc                                            1044


<210>  3284
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  3284
gaacagaagc tgaatgagta tgtggctaag ggtctgaccg acagcatcca ccgttaccac       60

tcagacaata gcaccaaggc agcgtgggac tccatccagt catttctgca gtgttgtggt      120

ataaatggca cgagtgattg gaccagtggc ccaccagcat cttgcccctc agatcgaaaa      180

gtggagggtt gctatgcgaa agcaagactg tggtttcatt ccaat                      225


<210>  3285
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3285
gactgtggcc ttcccccaga tgtacctaat gcccagccag ctttggaagg ccgtacaagt       60

tttcccgagg atactgtaat aacgtacaaa tgtgaagaaa gctttgtgaa aattcctggc      120

gagaaggact cagtgatctg ccttaagggc agtcaatggt cagatattga agagttctgc      180

aatcgtagct gcgaggtgcc aacaaggcta aattctgcat ccctcaaaca gccttatatc      240

actcagaatt attttccagt cggtactgtt gtggaatatg agtgccgtcc aggttacaga      300

agagaacctt ctctatcacc aaaactaact tgccttcaga atttaaaatg gtccacagca      360

gtcgaatttt gtaaaaagaa atcatgccct aatccgggag aaatacgaaa tggtcagatt      420

gatgtaccag gtggcatatt atttggtgca accatctcct tctcatgtaa cacagggtac      480

aaattatttg gctcgacttc tagtttttgt cttatttcag gcagctctgt ccagtggagt      540

gacccgttgc cagagtgcag agaaatttat tgtccagcac caccacaaat tgacaatgga      600

ataattcaag gggaacgtga ccattatgga tatagacagt ctgtaacgta tgcatgtaat      660

aaaggattca ccatgattgg agagcactct atttattgta ctgtgaataa tgatgaagga      720

gagtggagtg gcccaccacc tgaatgcaga ggaaaatctc taacttccaa ggtcccacca      780

acagttcaga aacctaccac agtaaatgtt ccaactacag aagtctcacc aacttctcag      840

aaaaccacca caaaaaccac cacaccaaat gctcaagcaa cacggagtac acctgtttcc      900

aggacaacca agcattttca tgaaacaacc ccaaataaag gaagtggaac cacttca         957


<210>  3286
<211>  561
<212>  DNA
<213>  Homo Sapiens

<400>  3286
ttttcccaac aaatatatgg tgttgtgtat gggaatgtaa ctttccatgt accaagcaat       60

gtgcctttaa aagaggtcct atggaaaaaa caaaaggata aagttgcaga actggaaaat      120

tctgaattca gagctttctc atcttttaaa aatagggttt atttagacac tgtgtcaggt      180

agcctcacta tctacaactt aacatcatca gatgaagatg agtatgaaat ggaatcgcca      240

aatattactg ataccatgaa gttctttctt tatgtgcttg agtctcttcc atctcccaca      300

ctaacttgtg cattgactaa tggaagcatt gaagtccaat gcatgatacc agagcattac      360

aacagccatc gaggacttat aatgtactca tgggattgtc ctatggagca atgtaaacgt      420

aactcaacca gtatatattt taagatggaa aatgatcttc cacaaaaaat acagtgtact      480

cttagcaatc cattatttaa tacaacatca tcaatcattt tgacaacctg tatcccaagc      540

agcggtcatt caagacacag a                                                561


<210>  3287
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3287
ctgcagtgct acaactgtcc taacccaact gctgactgca aaacagccgt caattgttca       60

tctgattttg atgcgtgtct cattaccaaa gctgggttac aagtgtataa caagtgttgg      120

aagtttgagc attgcaattt caacgacgtc acaacccgct tgagggaaaa tgagctaacg      180

tactactgct gcaagaagga cctgtgtaac tttaacgaac agcttgaaaa t               231


<210>  3288
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  3288
catccatctc cagccccacc tgaccagctc aacaccagca gtgcagagag tgagctctgg       60

gagccagggg agcggcttcc ggtccgtctg acaaacggga gcagcagctg cagcgggacg      120

gtggaggtgc ggctcgaggc gtcctgggag cccgcgtgcg gggcgctctg ggacagccgc      180

gccgccgagg ccgtgtgccg agcactgggc tgcggcgggg cggaggccgc ctctcagctc      240

gccccgccga cccctgagct gccgcccccg cctgcagccg ggaacaccag cgtagcagct      300

aatgccactc tggccggggc gcccgccctc ctgtgcagcg gcgccgagtg gcggctctgc      360

gaggtggtgg agcacgcgtg ccgcagcgac gggaggcggg cccgtgtcac ctgtgcagag      420

aaccgcgcgc tgcgcctggt ggacggtggc ggcgcctgcg ccggccgcgt ggagatgctg      480

gagcatggcg agtggggatc agtgtgcgat gacacttggg acctggagga cgcccacgtg      540

gtgtgcaggc aactgggctg cggctgggca gtccaggccc tgcccggctt gcacttcatg      600

cccggccgcg ggcctatcca ccgggaccag gtgaactgct cgggggccga agcttacctg      660

tgggactgcc cggggctgcc aggacagcac tactgcggcc acaaagagga cgcgggcgtg      720

gtgtgctcag agcaccagtc ctggcgcctg acagggggcg ctgaccgctg cgaggggcag      780

gtggaggtac acttccgagg ggtctggaac acagtgtgtg acagtgagtg gtacccatcg      840

gaggccaagg tgctctgcca gtccttgggc tgtggaactg cggttgagag gcccaagggg      900

ctgccccact ccttgtccgg caggatgtac tactcatgca atggggagga gctcaccctc      960

tccaactgct cctggcggtt caacaactcc aacctctgca gccagtcgct ggcagccagg     1020

gtcctctgct cagcttcccg gagtttgcac aatctgtcca ctcccgaagt ccctgcaagt     1080

gttcagacag tcactataga atcttctgtg acagtgaaaa tagagaacaa ggaatctcgg     1140

gagctaatgc tcctc                                                      1155


<210>  3289
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  3289
gctggctatg tgtttagaga taaggtgatg tcagagttta ataacaactt ccggcagcag       60

atggagaatt acccgaaaaa caaccacact gcttcgatcc tggacaggat gcaggcagat      120

tttaagtgct gtggggctgc taactacaca gattgggaga aaatcccttc catgtcgaag      180

aaccgagtcc ccgactcctg ctgcattaat gttactgtgg gctgtgggat taatttcaac      240

gagaaggcga tccataagga gggctgtgtg gagaagattg ggggctggct gaggaaaaat      300

gtg                                                                    303


<210>  3290
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  3290
tcagtgggcc aatacaattg tccaggccaa tacacattct caatgccatc agacagccat       60

gtttcttcat gctctgagga ctgggttggc taccagagga aatgctactt tatttctact      120

gtgaagagga gctggacttc agcccaaaat gcttgttctg aacatggtgc tactcttgct      180

gtcattgatt ctgaaaagga catgaacttt ctaaaacgat acgcaggtag agaggaacac      240

tgggttggac tgaaaaagga acctggtcac ccatggaagt ggtcaaatgg caaagaattt      300

aacaactggt tcaacgttac agggtctgac aagtgtgttt ttctgaaaaa cacagaggtc      360

agcagcatgg aatgtgagaa gaatttatac tggatatgta acaaacctta caaa            414


<210>  3291
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  3291
gcccaagagg tgcagcagtc tccccactgc acgactgtcc ccgtgggagc ctccgtcaac       60

atcacctgct ccaccagcgg gggcctgcgt gggatctacc tgaggcagct cgggccacag      120

ccccaagaca tcatttacta cgaggacggg gtggtgccca ctacggacag acggttccgg      180

ggccgcatcg acttctcagg gtcccaggac aacctgacta tcaccatgca ccgcctgcag      240

ctgtcggaca ctggcaccta cacctgccag gccatcacgg aggtcaatgt ctacggctcc      300

ggcaccctgg tcctggtgac agaggaacag tcccaaggat ggcacagatg ctcggacgcc      360

ccaccaaggg cctctgccct ccctgcccca ccgacaggct ccgccctccc tgacccgcag      420

acagcctctg ccctccctga cccgccagca gcctctgccc tccct                      465


<210>  3292
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  3292
cagcgcttcg cacaggctca gcagcagctg ccgctcgagt cacttgggtg ggacgtagct       60

gagctgcagc tgaatcacac aggacctcag caggacccca ggctatactg gcaggggggc      120

ccagcactgg gccgctcctt cctgcatgga ccagagctgg acaaggggca gctacgtatc      180

catcgtgatg gcatctacat ggtacacatc caggtgacgc tggccatctg ttcctccacg      240

acggcctcca ggcaccaccc caccaccctg gccgtgggaa tctgctctcc cgcctcccgt      300

agcatcagcc tgctgcgtct cagcttccac caaggttgta ccattgcctc ccagcgcctg      360

acgcccctgg cccgagggga cacactctgc accaacctca ctgggacact tttgccttcc      420

cgaaacactg atgagacctt ctttggagtg cagtgggtgc gtccc                      465


<210>  3293
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  3293
cgctatctgc aggtgtctca gcagctccag cagacgaaca gggttctgga agtcactaac       60

agcagcctga ggcagcagct ccgcctcaag ataacgcagc tgggacagag tgcagaggat      120

ctgcaggggt ccaggagaga gctggcgcag agtcaggaag cactacaggt ggaacagagg      180

gctcatcagg cggccgaagg gcagctacag gcctgccagg cagacagaca gaagacgaag      240

gagaccttgc aaagtgagga gcaacagagg agggccttgg agcagaagct gagcaacatg      300

gagaacagac tgaagccctt cttcacatgc ggctcagcag acacctgctg tccgtcggga      360

tggataatgc atcagaaaag ctgcttttac atctcactta cttcaaaaaa ttggcaggag      420

agccaaaaac aatgtgaaac tctgtcttcc aagctggcca cattcagtga aatttatcca      480

caatcacact cttactactt cttaaattca ctgttgccaa atggtggttc agggaattca      540

tattggactg gcctcagctc taacaaggat tggaagttga ctgatgatac acaacgcact      600

aggacttatg ctcaaagctc aaaatgtaac aaggtacata aaacttggtc atggtggaca      660

ctggagtcag agtcatgtag aagttctctt ccctacatct gtgagatgac agctttcagg      720

tttccagat                                                              729


<210>  3294
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  3294
cagcagcagg gccggctgga caaactgaca gtcacctccc agaacctgca gctggagaac       60

ctgcgcatga agcttcccaa gcctcccaag cctgtgagca agatgcgcat ggccaccccg      120

ctgctgatgc aggcgctgcc catgggagcc ctgccccagg ggcccatgca gaatgccacc      180

aagtatggca acatgacaga ggaccatgtg atgcacctgc tccagaatgc tgaccccctg      240

aaggtgtacc cgccactgaa ggggagcttc ccggagaacc tgagacacct taagaacacc      300

atggagacca tagactggaa ggtctttgag agctggatgc accattggct cctgtttgaa      360

atgagcaggc actccttgga gcaaaagccc actgacgctc caccgaaaga gtcactggaa      420

ctggaggacc cgtcttctgg gctgggtgtg accaagcagg atctgggccc agtccccatg      480


<210>  3295
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  3295
ctgtggatgc acaaggtccc agcatcattg atggtgagcc tgggggaaga cgcccacttc       60

caatgcccgc acaatagcag caacaacgcc aacgtcacct ggtggcgcgt cctccatggc      120

aactacacgt ggccccctga gttcttgggc ccgggcgagg accccaatgg tacgctgatc      180

atccagaatg tgaacaagag ccatgggggc atatacgtgt gccgggtcca ggagggcaac      240

gagtcatacc agcagtcctg cggcacctac ctccgcgtgc gccagccgcc ccccaggccc      300

ttcctggaca tgggggaggg caccaagaac cga                                   333


<210>  3296
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  3296
gccagatcgg aggaccggta ccggaatccc aaaggtagtg cttgttcgcg gatctggcag       60

agcccacgtt tcatagccag gaaacggggc ttcacggtga aaatgcactg ctacatgaac      120

agcgcctccg gcaatgtgag ctggctctgg aagcaggaga tggacgagaa tccccagcag      180

ctgaagctgg aaaagggccg catggaagag tcccagaacg aatctctcgc caccctcacc      240

atccaaggca tccggtttga ggacaatggc atctacttct gccagcagaa gtgcaacaac      300

acctcggagg tctaccaggg ctgcggcaca gagctgcgag tcatgggatt cagcaccttg      360

gcacagctga agcagaggaa cacgctgaag gat                                   393


<210>  3297
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  3297
gttatccacg tgaccaagga agtgaaagaa gtggcaacgc tgtcctgtgg tcacaatgtt       60

tctgttgaag agctggcaca aactcgcatc tactggcaaa aggagaagaa aatggtgctg      120

actatgatgt ctggggacat gaatatatgg cccgagtaca agaaccggac catctttgat      180

atcactaata acctctccat tgtgatcctg gctctgcgcc catctgacga gggcacatac      240

gagtgtgttg ttctgaagta tgaaaaagac gctttcaagc gggaacacct ggctgaagtg      300

acgttatcag tcaaagctga cttccctaca cctagtatat ctgactttga aattccaact      360

tctaatatta gaaggataat ttgctcaacc tctggaggtt ttccagagcc tcacctctcc      420

tggttggaaa atggagaaga attaaatgcc atcaacacaa cagtttccca agatcctgaa      480

actgagctct atgctgttag cagcaaactg gatttcaata tgacaaccaa ccacagcttc      540

atgtgtctca tcaagtatgg acatttaaga gtgaatcaga ccttcaactg gaatacaacc      600

aagcaagagc attttcctga taac                                             624


<210>  3298
<211>  267
<212>  DNA
<213>  Homo Sapiens

<400>  3298
tttgtcaaca aggaccagat cgccaaggat gtgaagcagt tctatgacca ggccctacag       60

caggccgtgg tggatgatga cgccaacaac gccaaggctg tggtgaagac cttccacgag      120

acgcttgact gctgtggctc cagcacactg actgctttga ccacctcagt gctcaagaac      180

aatttgtgtc cctcgggcag caacatcatc agcaacctct tcaaggagga ctgccaccag      240

aagatcgatg acctcttctc cgggaag                                          267


<210>  3299
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  3299
ggcaagctga agcaggagat gggcggcatc gtgactgagc tcattcgaga ctacaacagc       60

agtcgcgagg acagcctgca ggatgcctgg gactacgtgc aggctcaggt gaagtgctgc      120

ggctgggtca gcttctacaa ctggacagac aacgctgagc tcatgaatcg ccctgaggtc      180

acctacccct gttcctgcga agtcaagggg gaagaggaca acagcctttc tgtgaggaag      240

ggcttctgcg aggcccccgg caacaggacc cagagtggca accaccctga ggactggcct      300

gtgtaccagg agggctgcat ggagaaggtg caggcgtggc tgcaggagaa cctg            354


<210>  3300
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  3300
acgccggagg tgaaggtggc ttgctccgaa gatgtggact tgccctgcac cgccccctgg       60

gatccgcagg ttccctacac ggtctcctgg gtcaagttat tggagggtgg tgaagagagg      120

atggagacac cccaggaaga ccacctcagg ggacagcact atcatcagaa ggggcaaaat      180

ggttctttcg acgcccccaa tgaaaggccc tattccctga agatccgaaa cactaccagc      240

tgcaactcgg ggacatacag gtgcactctg caggacccgg atgggcagag aaacctaagt      300

ggcaaggtga tcttgagagt gacaggatgc cctgcacagc gtaaagaaga gacttttaag      360

aaatacagag cggag                                                       375


<210>  3301
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  3301
aaagactcag aaatcttcac agtgaatggg attctgggag agtcagtcac tttccctgta       60

aatatccaag aaccacggca agttaaaatc attgcttgga cttctaaaac atctgttgct      120

tatgtaacac caggagactc agaaacagca cccgtagtta ctgtgaccca cagaaattat      180

tatgaacgga tacatgcctt aggtccgaac tacaatctgg tcattagcga tctgaggatg      240

gaagacgcag gagactacaa agcagacata aatacacagg ctgatcccta caccaccacc      300

aagcgctaca acctgcaaat ctatcgtcgg cttgggaaac caaaaattac acagagttta      360

atggcatctg tgaacagcac ctgtaatgtc acactgacat gctctgtaga gaaagaagaa      420

aagaatgtga catacaattg gagtcccctg ggagaagagg gtaatgtcct tcaaatcttc      480

cagactcctg aggaccaaga gctgacttac acgtgtacag cccagaaccc tgtcagcaac      540

aattctgact ccatctctgc ccggcagctc tgtgcagaca tcgcaatggg cttccgtact      600

caccacaccg gg                                                          612


<210>  3302
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3302
gctcctctga agattcaagc ttatttcaat gagactgcag acctgccatg ccaatttgca       60

aactctcaaa accaaagcct gagtgagcta gtagtatttt ggcaggacca ggaaaacttg      120

gttctgaatg aggtatactt aggcaaagag aaatttgaca gtgttcattc caagtatatg      180

ggccgcacaa gttttgattc ggacagttgg accctgagac ttcacaatct tcagatcaag      240

gacaagggct tgtatcaatg tatcatccat cacaaaaagc ccacaggaat gattcgcatc      300

caccagatga attctgaact gtcagtgctt gctaacttca gtcaacctga aatagtacca      360

atttctaata taacagaaaa tgtgtacata aatttgacct gctcatctat acacggttac      420

ccagaaccta agaagatgag tgttttgcta agaaccaaga attcaactat cgagtatgat      480

ggtattatgc agaaatctca agataatgtc acagaactgt acgacgtttc catcagcttg      540

tctgtttcat tccctgatgt tacgagcaat atgaccatct tctgtattct ggaaactgac      600

aagacgcggc ttttatcttc acctttctct atagagcttg aggaccctca gcctccccca      660

gaccacattc ct                                                          672


<210>  3303
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  3303
agccagttcc gggtgtcgcc gctggatcgg acctggaacc tgggcgagac agtggagctg       60

aagtgccagg tgctgctgtc caacccgacg tcgggctgct cgtggctctt ccagccgcgc      120

ggcgccgccg ccagtcccac cttcctccta tacctctccc aaaacaagcc caaggcggcc      180

gaggggctgg acacccagcg gttctcgggc aagaggttgg gggacacctt cgtcctcacc      240

ctgagcgact tccgccgaga gaacgagggc tgctatttct gctcggccct gagcaactcc      300

atcatgtact tcagccactt cgtgccggtc ttcctgccag cgaagcccac cacgacgcca      360

gcgccgcgac caccaacacc ggcgcccacc atcgcgtcgc agcccctgtc cctgcgccca      420

gaggcgtgcc ggccagcggc ggggggcgca gtgcacacga gggggctgga cttcgcctgt      480

gat                                                                    483


<210>  3304
<211>  447
<212>  DNA
<213>  Homo Sapiens

<400>  3304
ctccagcaga cccctgcata cataaaggtg caaaccaaca agatggtgat gctgtcctgc       60

gaggctaaaa tctccctcag taacatgcgc atctactggc tgagacagcg ccaggcaccg      120

agcagtgaca gtcaccacga gttcctggcc ctctgggatt ccgcaaaagg gactatccac      180

ggtgaagagg tggaacagga gaagatagct gtgtttcggg atgcaagccg gttcattctc      240

aatctcacaa gcgtgaagcc ggaagacagt ggcatctact tctgcatgat cgtcgggagc      300

cccgagctga ccttcgggaa gggaactcag ctgagtgtgg ttgatttcct tcccaccact      360

gcccagccca ccaagaagtc caccctcaag aagagagtgt gccggttacc caggccagag      420

acccagaagg gcccactttg tagcccc                                          447


<210>  3305
<211>  459
<212>  DNA
<213>  Homo Sapiens

<400>  3305
aattcagttc tgcaacagac tccagcttat attaaagtac agactaataa aatggtgatg       60

ttatcttgtg aagcgaaaat aagtctatca aacatgtgca tttactggct aagacagcgt      120

caagctcctt cctctgattc acaccacgag ttcttgacct tatgggatag cgcgaaaggg      180

actatacacg gggaggaggt cgaacaggag aagattgccg ttttcagaga cgcgtctagg      240

tttatcttga accttaccag tgtaaagccc gaggacagcg gcatctactt ttgcatgatt      300

gtggggagcc cagagctaac cttcggaaag gggactcagc ttagcgtcgt cgtagatttc      360

ttacccacaa ctgctcaacc aacgaaaaaa agcactctga aaaagagagt gtgcagattg      420

ccaagacctg agacccaaaa gggaccgcta tgcagtcct                             459


<210>  3306
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  3306
tcccacaagg atgaggtgat taaggaagtc caggagtttt acaaggacac ctacaacaag       60

ctgaaaacca aggatgagcc ccagcgggaa acgctgaaag ccatccacta tgcgttgaac      120

tgctgtggtt tggctggggg cgtggaacag tttatctcag acatctgccc caagaaggac      180

gtactcgaaa ccttcaccgt gaagtcctgt cctgatgcca tcaaagaggt cttcgacaat      240

aaattccaca tc                                                          252


<210>  3307
<211>  1143
<212>  DNA
<213>  Homo Sapiens

<400>  3307
gtttgggaaa aaacagtcaa cacagaagaa aatgtttatg ctacacttgg ctctgatgtc       60

aacctgacct gccaaacaca gacagtaggc ttcttcgtgc agatgcaatg gtccaaggtc      120

accaataaga tagacctgat tgctgtctat catccccaat acggcttcta ctgtgcctat      180

gggagaccct gtgagtcact tgtgactttc acagaaactc ctgagaatgg gtcaaaatgg      240

actctgcact taaggaatat gtcttgttca gtcagtggaa ggtacgagtg tatgcttgtt      300

ctgtatccag agggcattca gactaaaatc tacaaccttc tcattcagac acacgttaca      360

gcagatgaat ggaacagcaa ccatacgata gaaatagaga taaatcagac tctggaaata      420

ccatgctttc aaaatagctc ctcaaaaatt tcatctgagt tcacctatgc atggtcggtg      480

gaggataatg gaactcagga aacacttatc tcccaaaatc acctcatcag caattccaca      540

ttacttaaag atagagtcaa gcttggtaca gactacagac tccacctctc tccagtccaa      600

atcttcgatg atgggcggaa gttctcttgc cacattagag tcggtcctaa caaaatcttg      660

aggagctcca ccacagtcaa ggtttttgct aaaccagaaa tccctgtgat tgtggaaaat      720

aactccacgg atgtcttggt agagagaaga ttcacctgct tactaaagaa tgtatttccc      780

aaagcaaata tcacatggtt tatagatgga agttttcttc atgatgaaaa agaaggaata      840

tatattacta atgaagagag aaaaggcaaa gatggatttt tggaactgaa gtctgtttta      900

acaagggtac atagtaataa accagcccaa tcagacaact tgaccatttg gtgtatggct      960

ctgtctccag tcccaggaaa taaagtgtgg aacatctcat cagaaaagat cacttttctc     1020

ttaggttctg aaatttcctc aacagaccct ccactgagtg ttacagaatc tacccttgac     1080

acccaacctt ctccagccag cagtgtatct cctgcaagta agaatgtttt cacactgagc     1140

tat                                                                   1143


<210>  3308
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  3308
gatggtggtt tcgatttatc cgatgccctt cctgacaatg aaaacaagaa acccactgca       60

atccccaaga aacccagtgc tggggatgac tttgacttag gagatgctgt tgttgatgga      120

gaaaatgacg acccacgacc accgaaccca cccaaaccga tgccaaatcc aaaccccaac      180

caccctagtt cctccggtag cttttcagat gctgaccttg cggatggcgt ttcaggtgga      240

gaaggaaaag gaggcagtga tggtggaggc agccacagga aagaagggga agaggccgac      300


<210>  3309
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  3309
gactgggtta ttcctcccat cagctgccca gaaaatgaaa aaggcccatt tcctaaaaac       60

ctggttcaga tcaaatccaa caaagacaaa gaaggcaagg ttttctacag catcactggc      120

caaggagctg acacaccccc tgttggtgtc tttattattg aaagagaaac aggatggctg      180

aaggtgacag agcctctgga tagagaacgc attgccacat acactctctt ctctcacgct      240

gtgtcatcca acgggaatgc agttgaggat ccaatggaga ttttgatcac ggtaaccgat      300

cagaatgaca acaagcccga attcacccag gaggtcttta aggggtctgt catggaaggt      360

gctcttccag gaacctctgt gatggaggtc acagccacag acgcggacga tgatgtgaac      420

acctacaatg ccgccatcgc ttacaccatc ctcagccaag atcctgagct ccctgacaaa      480

aatatgttca ccattaacag gaacacagga gtcatcagtg tggtcaccac tgggctggac      540

cgagagagtt tccctgcgta taccctggtg gttcaagctg ctgaccttca aggtgagggg      600

ttaagcacaa cagcaacagc tgtgatcaca gtcactgaca ccaacgataa tcctccgatc      660

ttcaatccca ccacgtacaa gggtcaggtg cctgagaacg aggctaacgt cgtaatcacc      720

acactgaaag tgactgatgc tgatgccccc aataccccag cgtgggaggc tgtatacacc      780

atattgaatg atgatggtgg acaatttgtc gtcaccacaa atccagtgaa caacgatggc      840

attttgaaaa cagcaaaggg cttggatttt gaggccaagc agcagtacat tctacacgta      900

gcagtgacga atgtggtacc ttttgaggtc tctctcacca cctccacagc caccgtcacc      960

gtggatgtgc tggatgtgaa tgaagccccc atctttgtgc ctcctgaaaa gagagtggaa     1020

gtgtccgagg actttggcgt gggccaggaa atcacatcct acactgccca ggagccagac     1080

acatttatgg aacagaaaat aacatatcgg atttggagag acactgccaa ctggctggag     1140

attaatccgg acactggtgc catttccact cgggctgagc tggacaggga ggattttgag     1200

cacgtgaaga acagcacgta cacagcccta atcatagcta cagacaatgg ttctccagtt     1260

gctactggaa cagggacact tctgctgatc ctgtctgatg tgaatgacaa cgccccc        1317


<210>  3310
<211>  1677
<212>  DNA
<213>  Homo Sapiens

<400>  3310
ggttggatgt ggaatcaatt tttcttactt gaagaatata caggatctga ttatcagtac       60

gtaggcaagc tacattcaga ccaagataaa ggagatggat cactcaaata tatcttatct      120

ggagatggag ctggtactct ttttattatt gatgaaaaaa caggtgatat tcatgccaca      180

aggcgaattg atagggagga aaaggccttt tatactctac gcgcacaagc tattaacaga      240

agaactctga ggccagtaga gccagagtca gagtttgtga tcaaaattca tgatatcaat      300

gacaatgagc caacgttccc agaagaaatc tatacagcta gtgttcccga aatgtctgtt      360

gtaggtactt ctgtggtgca agtcacagct acagatgccg atgacccttc atatgggaac      420

agcgccagag tcatttacag catacttcaa gggcagccct atttctctgt ggagcctgaa      480

acaggtatca tcaggactgc tttaccgaac atgaacagag aaaacagaga gcaataccaa      540

gtggtcatcc aggccaaaga catgggcggc cagatgggag gcttatcggg gacaaccact      600

gtgaacatca cgctgacaga tgtcaatgac aacccaccac gtttccccca gaacactatt      660

catcttcgag ttcttgaatc ctccccagtt ggcacagcca ttggaagtgt caaagcaact      720

gatgctgaca ctgggaaaaa tgctgaagta gaataccgaa ttattgatgg tgacggtact      780

gatatgtttg acatcgtgac tgagaaggac acacaggaag gcatcatcac tgtgaaaaag      840

ccactcgact atgagagccg aagactttat actctgaaag tcgaagcaga aaacacccat      900

gtagatcccc gtttttatta cctaggacca tttaaagata ctaccatagt gaaaatctct      960

atagaagatg tggatgaacc tcctgttttt agtaggtcct cctatctgtt tgaagttcat     1020

gaagatattg aagtgggcac aatcattggt actgtaatgg caagggaccc agattctatt     1080

tccagcccca ttagattttc cttggatcgc catactgacc ttgacagaat ctttaacatt     1140

cattcaggaa atggatctct ttatacatca aaacctcttg accgtgaact atctcagtgg     1200

cataatctta ctgttattgc tgctgaaatc aacaatccca aagagacaac acgcgtggct     1260

gtttttgtga gaattttgga tgttaatgac aatgccccac agtttgctgt gttctatgac     1320

acttttgtat gtgaaaatgc cagaccaggg cagctaatac agactataag tgcagtagac     1380

aaagatgacc ctttaggtgg acagaaattt tttttcagtt tagctgctgt caatccaaac     1440

ttcacagtac aggataatga agataatact gccagaatct taaccagaaa aaatggattc     1500

aatagacatg aaatcagtac ctatctcttg cctgtggtga tatcagacaa tgattaccca     1560

attcagagca gcacaggcac actgaccatt cgagtgtgtg cttgtgacag ccaaggcaac     1620

atgcaatcct gcagtgctga agccctgctc ctccctgccg gcctcagcac tggggcc        1677


<210>  3311
<211>  1692
<212>  DNA
<213>  Homo Sapiens

<400>  3311
ggctgggtct ggaaccagtt cttcgtgata gaggagtaca ccgggcctga ccccgtgctt       60

gtgggcaggc ttcattcaga tattgactct ggtgatggga acattaaata cattctctca      120

ggggaaggag ctggaaccat ttttgtgatt gatgacaaat cagggaacat tcatgccacc      180

aagacgttgg atcgagaaga gagagcccag tacacgttga tggctcaggc ggtggacagg      240

gacaccaatc ggccactgga gccaccgtcg gaattcattg tcaaggtcca ggacattaat      300

gacaaccctc cggagttcct gcacgagacc tatcatgcca acgtgcctga gaggtccaat      360

gtgggaacgt cagtaatcca ggtgacagct tcagatgcag atgaccccac ttatggaaat      420

agcgccaagt tagtgtacag tatcctcgaa ggacaaccct atttttcggt ggaagcacag      480

acaggtatca tcagaacagc cctacccaac atggacaggg aggccaagga ggagtaccac      540

gtggtgatcc aggccaagga catgggtgga catatgggcg gactctcagg gacaaccaaa      600

gtgatgatca cactgaccga tgtcaatgac aacccaccaa agtttccgca gagcgtatac      660

cagatgtctg tgtcagaagc agccgtccct ggggaggaag taggaagagt gaaagctaaa      720

gatccagaca ttggagaaaa tggcttagtc acatacaata ttgttgatgg agatggtatg      780

gaatcatttg aaatcacaac ggactatgaa acacaggagg gggtgataaa gctgaaaaag      840

cctgtagatt ttgaaaccaa aagagcctat agcttgaagg tagaggcagc caacgtgcac      900

atcgacccga agtttatcag caatggccct ttcaaggaca ctgtgaccgt caagatcgca      960

gtagaagatg ctgatgagcc ccctatgttc ttggccccaa gttacatcca cgaagtccaa     1020

gaaaatgcag ctgctggcac cgtggttggg agagtgcatg ccaaagaccc tgatgctgcc     1080

aacagcccga taaggtattc catcgatcgt cacactgacc tcgacagatt tttcactatt     1140

aatccagagg atggttttat taaaactaca aaacctctgg atagagagga aacagcctgg     1200

ctcaacatca ctgtctttgc agcagaaatc cacaatcggc atcaggaagc caaagtccca     1260

gtggccatta gggtccttga tgtcaacgat aatgctccca agtttgctgc cccttatgaa     1320

ggtttcatct gtgagagtga tcagaccaag ccactttcca accagccaat tgttacaatt     1380

agtgcagatg acaaggatga cacggccaat ggaccaagat ttatcttcag cctaccccct     1440

gaaatcattc acaatccaaa tttcacagtc agagacaacc gagataacac agcaggcgtg     1500

tacgcccggc gtggagggtt cagtcggcag aagcaggact tgtaccttct gcccatagtg     1560

atcagcgatg gcggcatccc gcccatgagt agcaccaaca ccctcaccat caaagtctgc     1620

gggtgcgacg tgaacggggc actgctctcc tgcaacgcag aggcctacat tctgaacgcc     1680

ggcctgagca ca                                                         1692


<210>  3312
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  3312
ggctgggtat ggaatcaatt ttttgtgctg gaagaatacg tgggctccga gcctcagtat       60

gtgggaaagc tccattccga cttagacaag ggagagggca ctgtgaaata caccctctca      120

ggagatggcg ctggcaccgt ttttaccatt gatgaaacca caggggacat tcatgcaata      180

aggagcctag atagagaaga gaaacctttc tacactcttc gtgctcaggc tgtggacata      240

gaaaccagaa agcccctgga gcctgaatca gaattcatca tcaaagtgca ggatattaat      300

gataatgagc caaagttttt ggatggacct tatgttgcta ctgttccaga aatgtctcct      360

gtgggtgcat atgtactcca ggtcaaggcc acagatgcag atgacccgac ctatggaaac      420

agtgccagag tcgtttacag cattcttcag ggacaacctt atttctctat tgatcccaag      480

acaggtgtta ttagaacagc tttgccaaac atggacagag aagtcaaaga acaatatcaa      540

gtactcatcc aagccaagga tatgggagga cagcttggag gattagccgg aacaacaata      600

gtcaacatca ctctcaccga tgtcaatgac aatccacctc gattccccaa aagcatcttc      660

cacttgaaag ttcctgagtc ttcccctatt ggttcagcta ttggaagaat aagagctgtg      720

gatcctgatt ttggacaaaa tgcagaaatt gaatacaata ttgttccagg agatggggga      780

aatttgtttg acatcgtcac agatgaggat acacaagagg gagtcatcaa attgaaaaag      840

cctttagatt ttgaaacaaa gaaggcatac actttcaaag ttgaggcttc caaccttcac      900

cttgaccacc ggtttcactc ggcgggccct ttcaaagaca cagctacggt gaagatcagc      960

gtgctggacg tagatgagcc accggttttc agcaagccgc tctacaccat ggaggtttat     1020

gaagacactc cggtagggac catcattggc gctgtcactg ctcaagacct ggatgtaggc     1080

agcagtgctg ttaggtactt catagattgg aagagtgatg gggacagcta ctttacaata     1140

gatggaaatg aaggaaccat cgccactaat gaattactag acagagaaag cactgcgcag     1200

tataatttct ccataattgc gagtaaagtt agtaaccctt tattgaccag caaagtcaat     1260

atactgatta atgtcttaga tgtaaatgaa tttcctccag aaatatctgt gccatatgag     1320

acagccgtgt gtgaaaatgc caagccagga cagataattc agatagtcag tgctgcagac     1380

cgagatcttt cacctgctgg gcaacaattc tcctttagat tatcacctga ggctgctatc     1440

aaaccaaatt ttacagttcg tgacttcaga aacaacacag cggggattga aacccgaaga     1500

aatggataca gccgcaggca gcaagagttg tatttcctcc ctgttgtaat agaagacagc     1560

agctaccctg tccagagcag cacaaacaca atgactattc gagtctgtag atgtgactct     1620

gatggcacca tcctgtcttg taatgtggaa gcaatttttc tacct                     1665


<210>  3313
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  3313
tccattgtgg tatctcccat tttaattcca gagaatcaga gacagccttt cccaagagat       60

gttggcaagg tagtcgatag tgacaggcca gaaaggtcca agttccggct cactggaaag      120

ggagtggatc aagagcctaa aggaattttc agaatcaatg agaacacagg gagcgtctcc      180

atgacacgga ccttggacag agaagtaatc gctgtttatc aactatttgt ggagaccact      240

gatgtcaatg gcaaaactct cgaggggccg gtgcctctgg aagtcattgt gattgatcag      300

aatgacaacc gaccgatctt tcgggaaggc ccctacatcg gccacgtcat ggaagggtca      360

cccacaggca ccacagtgat gcggatgaca gcctttgatg cagatgaccc agccaccgat      420

aatgccctcc tgcggtataa tatccgtcgg cagacgcctg acaagccatc tcccaacatg      480

ttctacatcg atcctgagaa aggagacatt gtcactgttg tgtcacctgc gctgctggac      540

cgagagactc tggaaaatcc caagtatgaa ctgatcatcg aggctcaaga tatggctgga      600

ctggatgttg gattaacagg cacggccaca gccacgatca tgatcgatga caaaaatgat      660

cactcaccaa aattcaccaa gaaagagttt caagccacag tcgaggaagg agctgtggga      720

gttattgtca atttgacagt tgaagataag gatgaccccg ccacaggtgc atggagggct      780

gcctacacca tcatcaacgg aaaccccggg cagagctttg aaatccacac caaccctcaa      840

accaacgaag ggatgctttc tgttgtcaaa ccattggact atgaaatttc tgccttccac      900

accctgctga tcaaagtgga aaatgaagac ccactcgtac ccgacgtctc ctacggcccc      960

agctccacag ccaccgtcca catcactgtc ctggatgtca acgagggccc agtcttctac     1020

ccagacccca tgatggtgac caggcaggag gacctctctg tgggcagcgt gctgctgaca     1080

gtgaatgcca cggaccccga ctccctgcag catcaaacca tcaggtattc tgtttacaag     1140

gacccagcag gttggctgaa tattaacccc atcaatggga ctgttgacac cacagctgtg     1200

ctggaccgtg agtccacatt tgtcgacaac agcgtgtaca ctgctctctt cctggcaatt     1260

gacagtggca accctcccgc tacgggcact gggactttgc tgataaccct ggaggacgtg     1320

aatgacaatg ccccgttcat ttaccccaca gtagctgaag tctgtgatga tgccaaaaac     1380

ctcagtgtag tcattttggg agcatcagat aaggatcttc acccgaatac agatcctttc     1440

aaatttgaaa tccacaaaca agctgttcct gataaagtct ggaagatctc caagatcaac     1500

aatacacacg ccctggtaag ccttcttcaa aatctgaaca aagcaaacta caacctgccc     1560

atcatggtga cagattcagg gaaaccaccc atgacgaata tcacagatct cagggtacaa     1620

gtgtgctcct gcaggaattc caaagtggac tgcaacgcgg cgggg                     1665


<210>  3314
<211>  1638
<212>  DNA
<213>  Homo Sapiens

<400>  3314
ctcccctacc ccctggttca gatcaagtcg gacaagcagc agctgggcag cgtcatctac       60

agcatccagg gacccggcgt ggatgaggag ccccggggcg tcttctctat cgacaagttc      120

acagggaagg tcttcctcaa tgccatgctg gaccgcgaga agactgatcg cttcaggcta      180

agagcgtttg ccctggacct gggaggatcc accctggagg accccacgga cctggagatt      240

gtagttgtgg atcagaatga caaccggcca gccttcctgc aggaggcgtt cactggccgc      300

gtgctggagg gtgcagtccc aggcacctat gtgaccaggg cagaggccac agatgccgac      360

gaccccgaga cggacaacgc agcgctgcgg ttctccatcc tgcagcaggg cagccccgag      420

ctcttcagca tcgacgagct cacaggagag atccgcacag tgcaagtggg gctggaccgc      480

gaggtggtcg cggtgtacaa tctgaccctg caggtggcgg acatgtctgg agacggcctc      540

acagccactg cctcagccat catcaccctt gatgacatca atgacaatgc ccccgagttc      600

accagggatg agttcttcat ggaggccata gaggccgtca gcggagtgga tgtgggacgc      660

ctggaagtgg aggacaggga cctgccaggc tccccaaact gggtggccag gttcactatc      720

ctggaaggcg accccgatgg gcagttcacc atccgcacgg accccaagac caacgagggt      780

gttctgtcca ttgtgaaggc cctggactat gagagctgtg aacactacga actcaaagtg      840

tcggtgcaga atgaggcccc gctgcaggcg gctgccctta gggctgagcg gggccaggcc      900

aaggtccgcg tgcatgtgca ggacaccaac gagccccccg tgttccagga gaacccactt      960

cggaccagcc tagcagaggg ggcaccccca ggcactctgg tggccacctt ctctgcccgg     1020

gaccctgaca cagagcagct gcagaggctc agctactcca aggactacga cccggaagac     1080

tggctgcaag tggacgcagc cactggccgg atccagaccc agcacgtgct cagcccggcg     1140

tcccccttcc tcaagggcgg ctggtacaga gccatcgtcc tggcccagga tgacgcctcc     1200

cagccccgca ccgccaccgg caccctgtcc atcgagatcc tggaggtgaa cgaccatgca     1260

cctgtgctgg ccccgccgcc gccgggcagc ctgtgcagcg agccacacca aggcccaggc     1320

ctcctcctgg gcgccacgga tgaggacctg cccccccacg gggccccctt ccacttccag     1380

ctgagcccca ggctcccaga gctcggccgg aactggagcc tcagccaggt caacgtgagc     1440

cacgcgcgcc tgcggccgcg acaccaggtc cccgaaggcc tgcaccgcct cagcctgctg     1500

ctccgggact cggggcagcc gccccagcag cgcgagcagc ctctgaacgt gaccgtgtgc     1560

cgctgcggca aggacggcgt ctgcctgccg ggggccgcag cgctgctggc ggggggcaca     1620

ggcctcagcc tgggcgca                                                   1638


<210>  3315
<211>  2304
<212>  DNA
<213>  Homo Sapiens

<400>  3315
aaggcccagc ctgcagagct gtctgtggaa gttccagaaa actatggtgg aaatttccct       60

ttatacctga ccaagttgcc gctgccccgt gagggggctg aaggccagat cgtgctgtca      120

ggggactcag gcaaggcaac tgagggccca tttgctatgg atccagattc tggcttcctg      180

ctggtgacca gggccctgga ccgagaggag caggcagagt accagctaca ggtcaccctg      240

gagatgcagg atggacatgt cttgtggggt ccacagcctg tgcttgtgca cgtgaaggat      300

gagaatgacc aggtgcccca tttctctcaa gccatctaca gagctcggct gagccggggt      360

accaggcctg gcatcccctt cctcttcctt gaggcttcag accgggatga gccaggcaca      420

gccaactcgg atcttcgatt ccacatcctg agccaggctc cagcccagcc ttccccagac      480

atgttccagc tggagcctcg gctgggggct ctggccctca gccccaaggg gagcaccagc      540

cttgaccacg ccctggagag gacctaccag ctgttggtac aggtcaagga catgggtgac      600

caggcctcag gccaccaggc cactgccacc gtggaagtct ccatcataga gagcacctgg      660

gtgtccctag agcctatcca cctggcagag aatctcaaag tcctataccc gcaccacatg      720

gcccaggtac actggagtgg gggtgatgtg cactatcacc tggagagcca tcccccggga      780

ccctttgaag tgaatgcaga gggaaacctc tacgtgacca gagagctgga cagagaagcc      840

caggctgagt acctgctcca ggtgcgggct cagaattccc atggcgagga ctatgcggcc      900

cctctggagc tgcacgtgct ggtgatggat gagaatgaca acgtgcctat ctgccctccc      960

cgtgacccca cagtcagcat ccctgagctc agtccaccag gtactgaagt gactagactg     1020

tcagcagagg atgcagatgc ccccggctcc cccaattccc acgttgtgta tcagctcctg     1080

agccctgagc ctgaggatgg ggtagagggg agagccttcc aggtggaccc cacttcaggc     1140

agtgtgacgc tgggggtgct cccactccga gcaggccaga acatcctgct tctggtgctg     1200

gccatggacc tggcaggcgc agagggtggc ttcagcagca cgtgtgaagt cgaagtcgca     1260

gtcacagata tcaatgatca cgcccctgag ttcatcactt cccagattgg gcctataagc     1320

ctccctgagg atgtggagcc cgggactctg gtggccatgc taacagccat tgatgctgac     1380

ctcgagcccg ccttccgcct catggatttt gccattgaga ggggagacac agaagggact     1440

tttggcctgg attgggagcc agactctggg catgttagac tcagactctg caagaacctc     1500

agttatgagg cagctccaag tcatgaggtg gtggtggtgg tgcagagtgt ggcgaagctg     1560

gtggggccag gcccaggccc tggagccacc gccacggtga ctgtgctagt ggagagagtg     1620

atgccacccc ccaagttgga ccaggagagc tacgaggcca gtgtccccat cagtgcccca     1680

gccggctctt tcctgctgac catccagccc tccgacccca tcagccgaac cctcaggttc     1740

tccctagtca atgactcaga gggctggctc tgcattgaga aattctccgg ggaggtgcac     1800

accgcccagt ccctgcaggg cgcccagcct ggggacacct acacggtgct tgtggaggcc     1860

caggatacag atgagccgag actgagcgct tctgcacccc tggtgatcca cttcctaaag     1920

gcccctcctg ccccagccct gactcttgcc cctgtgccct cccaatacct ctgcacaccc     1980

cgccaagacc atggcttgat cgtgagtgga cccagcaagg accccgatct ggccagtggg     2040

cacggtccct acagcttcac ccttggtccc aaccccacgg tgcaacggga ttggcgcctc     2100

cagactctca atggttccca tgcctacctc accttggccc tgcattgggt ggagccacgt     2160

gaacacataa tccccgtggt ggtcagccac aatgcccaga tgtggcagct cctggttcga     2220

gtgatcgtgt gtcgctgcaa cgtggagggg cagtgcatgc gcaaggtggg ccgcatgaag     2280

ggcatgccca cgaagctgtc ggca                                            2304


<210>  3316
<211>  2295
<212>  DNA
<213>  Homo Sapiens

<400>  3316
caagagggga agtttagtgg acccctgaaa cccatgacat tttctattta tgaaggccaa       60

gaaccgagtc aaattatatt ccagtttaag gccaatcctc ctgctgtgac ttttgaacta      120

actggggaga cagacaacat atttgtgata gaacgggagg gacttctgta ttacaacaga      180

gccttggaca gggaaacaag atctactcac aatctccagg ttgcagccct ggacgctaat      240

ggaattatag tggagggtcc agtccctatc accatagaag tgaaggacat caacgacaat      300

cgacccacgt ttctccagtc aaagtacgaa ggctcagtaa ggcagaactc tcgcccagga      360

aagcccttct tgtatgtcaa tgccacagac ctggatgatc cggccactcc caatggccag      420

ctttattacc agattgtcat ccagcttccc atgatcaaca atgttatgta ctttcagatc      480

aacaacaaaa cgggagccat ctctcttacc cgagagggat ctcaggaatt gaatcctgct      540

aagaatcctt cctataatct ggtgatctca gtgaaggaca tgggaggcca gagtgagaat      600

tccttcagtg ataccacatc tgtggatatc atagtgacag agaatatttg gaaagcacca      660

aaacctgtgg agatggtgga aaactcaact gatcctcacc ccatcaaaat cactcaggtg      720

cggtggaatg atcccggtgc acaatattcc ttagttgaca aagagaagct gccaagattc      780

ccattttcaa ttgaccagga aggagatatt tacgtgactc agcccttgga ccgagaagaa      840

aaggatgcat atgtttttta tgcagttgca aaggatgagt acggaaaacc actttcatat      900

ccgctggaaa ttcatgtaaa agttaaagat attaatgata atccacctac atgtccgtca      960

ccagtaaccg tatttgaggt ccaggagaat gaacgactgg gtaacagtat cgggaccctt     1020

actgcacatg acagggatga agaaaatact gccaacagtt ttctaaacta caggattgtg     1080

gagcaaactc ccaaacttcc catggatgga ctcttcctaa tccaaaccta tgctggaatg     1140

ttacagttag ctaaacagtc cttgaagaag caagatactc ctcagtacaa cttaacgata     1200

gaggtgtctg acaaagattt caagaccctt tgttttgtgc aaatcaacgt tattgatatc     1260

aatgatcaga tccccatctt tgaaaaatca gattatggaa acctgactct tgctgaagac     1320

acaaacattg ggtccaccat cttaaccatc caggccactg atgctgatga gccatttact     1380

gggagttcta aaattctgta tcatatcata aagggagaca gtgagggacg cctgggggtt     1440

gacacagatc cccataccaa caccggatat gtcataatta aaaagcctct tgattttgaa     1500

acagcagctg tttccaacat tgtgttcaaa gcagaaaatc ctgagcctct agtgtttggt     1560

gtgaagtaca atgcaagttc ttttgccaag ttcacgctta ttgtgacaga tgtgaatgaa     1620

gcacctcaat tttcccaaca cgtattccaa gcgaaagtca gtgaggatgt agctataggc     1680

actaaagtgg gcaatgtgac tgccaaggat ccagaaggtc tggacataag ttattcactg     1740

aggggagaca caagaggttg gcttaaaatt gaccacgtga ctggtgagat ctttagtgtg     1800

gctccattgg acagagaagc cggaagtcca tatcgggtac aagtggtggc cacagaagta     1860

ggggggtctt ccttgagctc tgtgtcagag ttccacctga tccttatgga tgtgaatgac     1920

aaccctccca ggctagccaa ggactacacg ggcttgttct tctgccatcc cctcagtgca     1980

cctggaagtc tcatttttga ggctactgat gatgatcagc acttatttcg gggtccccat     2040

tttacatttt ccctcggcag tggaagctta caaaacgact gggaagtttc caaaatcaat     2100

ggtactcatg cccgactgtc taccaggcac acagactttg aggagaggga gtatgtcgtc     2160

ttgatccgca tcaatgatgg gggtcggcca cccttggaag gcattgtttc tttaccagtt     2220

acattctgca gttgtgtgga aggaagttgt ttccggccag caggtcacca gactgggata     2280

cccactgtgg gcatg                                                      2295


<210>  3317
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  3317
ggatgggtat ggaatcagtt ctttgtttta gaagaacata tgggaccaga tcctcagtat       60

gttggaaagc tgcactccaa ttctgacaaa ggtgatggat ctgtcaagta catccttact      120

ggagagggtg ctgggactat atttatcatt gacgatacca cgggtgatat ccactcaaca      180

aaaagcctag acagagagca gaagacccac tatgtgcttc atgctcaagc tattgataga      240

cgtacaaaca aacctcttga gcctgaatcc gagttcatca tcaaagtgca agacatcaat      300

gacaacgctc caaaattcac agatggacca tacattgtta ctgtgcctga aatgtcagat      360

atgggtacct ctgttctaca ggtgacagct actgatgcag atgaccctac ctatggaaac      420

agcgctcggg tggtttacag cattctccag ggacaaccct acttctccgt cgaccctaaa      480

acaggagtta ttagaacggc cttacataac atggacggag aagccagaga acattactcc      540

gtagtcattc aagccaaaga catggctggg caagttggag ggctttcagg atctacaaca      600

gtcaacatca ccttaaccga tgtcaatgac aacacaccac gctttcctca aaaacactat      660

cagctatatg ttcctgagtc agctcaagtt ggttcagctg ttgggaaaat caaggcaaat      720

gatgctgaca ctggctcaaa tgctgacatg acctactcca tcataaatgg tgatggcatg      780

ggaatattct caatctccac tgacaaagag accagagaag gaatcctttc tttaaagaag      840

ccactgaact atgagaaaaa gaagtcatat accctcaaca tagaaggagc aaatacacat      900

cttgattttc gcttttctca cttgggtcct tttaaagatg ctactatgct gaagatcatt      960

gttggggatg tagatgaacc accactattt tccatgcctt cctacctcat ggaagtctac     1020

gaaaatgcca agattgggac cgtcgttggt acagttttgg cacaagatcc tgacagtatt     1080

aacagcttag taagatactt catcaactac aatgttgaag acgacagatt tttcaacatt     1140

gatgccaata ctgggaccat taggactaca aaggttctcg acagagaaga aactccatgg     1200

tacaacatca cagtcactgc ttcagaaatt gataatcctg atttgctgag ccatgtcaca     1260

gtgggtatta gagttctgga tgtcaatgac aatccacccg aacttgccag ggaatatgat     1320

attattgtat gtgaaaattc taagcctggc caggttattc ataccatcag tgccactgat     1380

aaagatgatt ttgccaatgg accaaggttt aacttctttc ttgatgagcg cctgcctgta     1440

aatccaaact tcactctgaa ggacaatgaa gataacacag ccagcattct gacaaggcgg     1500

aggagattta gtcgaactgt tcaggatgtg tattatctgc ccattatgat ctctgatggt     1560

ggaatcccct ctctcagcag cagcagcacc ctcaccatca gggtttgtgc atgcgagaga     1620

gatgggcgtg tgcggacctg ccatgcagaa gccttcctgt cctcg                     1665


<210>  3318
<211>  981
<212>  DNA
<213>  Homo Sapiens

<400>  3318
ggctgggtgt ggaaccaatt ttttgtacca gaggaaatga atacgactag tcatcacatc       60

ggccagctaa gatctgattt agacaatgga aacaattctt tccagtacaa gcttttggga      120

gctggagctg gaagtacttt tatcattgat gaaagaacag gtgacatata tgccatacag      180

aagcttgata gagaggagcg atccctctac atcttaagag cccaggtaat agacatcgct      240

actggaaggg ctgtggaacc tgagtctgag tttgtcatca aagtttcgga tatcaatgac      300

aatgaaccaa aattcctaga tgaaccttat gaggccattg taccagagat gtctccagaa      360

ggaacattag ttatccaggt gacagcaagt gatgctgacg atccctcaag tggtaataat      420

gctcgtctcc tctacagctt acttcaaggc cagccatatt tttctgttga accaacaaca      480

ggagtcataa gaatatcttc taaaatggat agagaactgc aagatgagta ttgggtaatc      540

attcaagcca aggacatgat tggtcagcca ggagcgttgt ctggaacaac aagtgtatta      600

attaaacttt cagatgttaa tgacaataag cctatattta aagaaagttt ataccgcttg      660

actgtctctg aatctgcacc cactgggact tctataggaa caatcatggc atatgataat      720

gacataggag agaatgcaga aatggattac agcattgaag aggatgattc gcaaacattt      780

gacattatta ctaatcatga aactcaagaa ggaatagtta tattaaaaaa gaaagtggat      840

tttgagcacc agaaccacta cggtattaga gcaaaagtta aaaaccatca tgttcctgag      900

cagctcatga agtaccacac tgaggcttcc accactttca ttaagatcca ggtggaagat      960

gttgatgagc ctcctctttt c                                                981


<210>  3319
<211>  1695
<212>  DNA
<213>  Homo Sapiens

<400>  3319
gactgggtca tctctccaat caacttgcca gaaaactcca ggggaccttt tcctcaagag       60

cttgtcagga tcaggtctga tagagataaa aacctttcac tgcggtacag tgtaactggg      120

ccaggagctg accagcctcc aactggtatc ttcattatca accccatctc gggtcagctg      180

tcggtgacaa agcccctgga tcgcgagcag atagcccggt ttcatttgag ggcacatgca      240

gtagatatta atggaaatca agtggagaac cccattgaca ttgtcatcaa tgttattgac      300

atgaatgaca acagacctga gttcttacac caggtttgga atgggacagt tcctgaggga      360

tcaaagcctg gaacatatgt gatgaccgta acagcaattg atgctgacga tcccaatgcc      420

ctcaatggga tgttgaggta cagaatcgtg tctcaggctc caagcacccc ttcacccaac      480

atgtttacaa tcaacaatga gactggtgac atcatcacag tggcagctgg acttgatcga      540

gaaaaagtgc aacagtatac gttaataatt caagctacag acatggaagg caatcccaca      600

tatggccttt caaacacagc cacggccgtc atcacagtga cagatgtcaa tgacaatcct      660

ccagagttta ctgccatgac gttttatggt gaagttcctg agaacagggt agacatcata      720

gtagctaatc taactgtgac cgataaggat caaccccata caccagcctg gaacgcagtg      780

tacagaatca gtggcggaga tcctactgga cggttcgcca tccagaccga ccaaaacagc      840

aacgacgggt tagtcaccgt ggtcaaacca atcgactttg aagcaaatag gatgtttgtc      900

cttactgttg ctgcagaaaa tcaagtgcca ttagccaagg gaattcagca cccgcctcag      960

tcaactgcaa ccatgtctgt tacagttatt gacgtaaatg aaaaccctta ttttgccccc     1020

aatcctaaga tcattcgcca agaagaaggg cttcatgccg gtaccatgtt gacaacattc     1080

actgctcagg acccagatcg atatatgcag caaaatatta gatacactaa attatctgat     1140

cctgccaatt ggctaaaaat agatcctgtg aatggacaaa taactacaat tgctgttttg     1200

gaccgagaat caccaaatgt gaaaaacaat atatataatg ctactttcct tgcttctgac     1260

aatggaattc ctcctatgag tggaacagga acgctgcaga tctatttact tgatattaat     1320

gacaatgccc ctcaagtgtt acctcaagag gcagagactt gcgaaactcc agaccccaat     1380

tcaattaata ttacagcact tgattatggc attgatccaa atgctggacc atttgctttt     1440

gatcttcctt tatctccagt gactattaag agaaattgga ccatcactcg gcttaatggt     1500

gattttgctc agcttaattt aaagataaaa tttcttgaag ctggtatcta tgaagttccc     1560

atcataatca cagattcggg taatcctccc aaatcaaata tttccatact gcgcgtgaag     1620

gtttgccagt gtgactccaa cggggactgc acagatgtgg acaggattgt gggtgcgggg     1680

cttggcaccg gtgcc                                                      1695


<210>  3320
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  3320
agctgggttt ggaaccagtt tttcgttctg gaagagtaca ctgggaccga ccctttgtat       60

gtcggcaagc ttcattcaga tatggacagg ggagacggat ccatcaaata catcctctcg      120

ggagaaggtg ctggcatcgt gtttaccatc gacgacacca ctggagacat ccacgccatt      180

cagaggctcg atcgagagga aagagcccag tatactctaa gggctcaagc cctagacagg      240

cggacgggca ggccaatgga gcccgagtca gagttcatca tcaaaattca agacatcaat      300

gacaatgagc ccaagttcct ggacggacct tatgtggcca ctgtgccaga aatgtcccct      360

gtgggtacct ccgtcatcca agtgacagcc acagatgcag atgacccgac ctacggcaac      420

agtgccaggg tggtgtacag cattcttcag ggccagccat atttttctgt ggactctaaa      480

acaggtgtaa ttaggacagc gctcatgaac atggacagag aagccaaaga atactacgaa      540

gtgattatcc aagccaagga catgggaggg cagcttggag gattagctgg gaccacaaca      600

gtgaacatca ccctctcaga tgtcaatgat aacccacccc gctttcccca gaaacattac      660

cagatgagtg tgttggaatc agctccaatt agctccactg tcgggagagt gtttgccaag      720

gacttggatg aaggcatcaa tgcagagatg aaatatacta ttgtggatgg agatggtgca      780

gatgcctttg acattagcac agatcccaat ttccaagttg gtatcataac tgtgaagaag      840

cccctgagtt ttgaaagcaa gaaaagctac accttaaagg tggagggagc caatcctcac      900

ctagagatgc gttttctgaa cttgggccca tttcaggaca caacaacagt gcacatcagt      960

gtggaagacg tggacgagcc ccctgtgttt gaacctggct tttactttgt ggaggtgcct     1020

gaggatgtgg cgattggaac aaccatacag atcatttctg ccaaggaccc agatgtgacc     1080

aacaactcaa tcagatactc cattgataga agcagtgacc ctggaagatt tttctatgtt     1140

gacattacaa caggtgccct aatgacagca agacccctag accgggaaga attttcttgg     1200

cataatatca ctgtccttgc tatggaaatg aacaatccct cccaggttgg aagtgttcct     1260

gtcacaatca aagtcttaga tgtgaatgac aatgctccag agttccccag attctatgaa     1320

gcttttgtct gtgagaacgc caaggcagga cagctgatcc agacagtgag tgcggtggac     1380

caagatgacc cacgcaatgg tcagcatttc tactacagct tggctcctga ggctgctaac     1440

aaccccaact ttaccataag ggacaaccaa gataacacag cacggattct aaccaggagg     1500

tctggtttcc ggcagcagga gcagagtgtc tttcacctgc ctatcctgat agcagatagc     1560

gggcagcccg tgctgagcag cacaggcaca ctgaccatcc aagtgtgcag ctgtgatgac     1620

gacggccacg tcatgtcctg cagcccagag gcctacatgc tcccagtcag tttgagccgg     1680


<210>  3321
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  3321
ctggccacac cctacgaggc agctgtatgc gaggatgcca agccaggcca gctcatccag       60

accatcagcg tggtggacag agacgagccc caaggcgggc accgcttcta tttccgcctg      120

gtgcctgaag ctcccagcaa ccctcatttc tctctgcttg acatccaaga caacaccgct      180

gcagtgcaca cgcagcacgt gggcttcaac cggcaggagc aggacgtgtt cttcctgccc      240

atcctggtgg tagacagtgg gccgcccaca ctgagcagca caggcacgct caccatccgc      300

atctgtggct gcgacagctc cggcaccatc cagtcctgca acaccacggc ctttgtcatg      360

gccgcctccc tcagcccc                                                    378


<210>  3322
<211>  2916
<212>  DNA
<213>  Homo Sapiens

<400>  3322
caggtgaacc ggctgccctt cttcaccaac cacttctttg atacatacct gctgatcagc       60

gaggacacgc ctgtgggttc ttctgtgacc cagttgctgg cccaagacat ggacaatgac      120

cccctggtgt ttggcgtgtc tggggaggag gcctctcgct tctttgcagt ggagcctgac      180

actggcgtgg tgtggctccg gcagccactg gacagagaga ccaagtcaga gttcaccgtg      240

gagttctctg tcagcgacca ccagggggtg atcacacgga aggtgaacat ccaggtcggg      300

gatgtgaatg acaacgcgcc cacatttcac aatcagccct acagcgtccg catccctgag      360

aatacaccag tggggacgcc catcttcatc gtgaatgcca cagaccccga cttgggggca      420

gggggcagcg tcctctactc cttccagccc ccctcccaat tcttcgccat tgacagcgcc      480

cgcggtatcg tcacagtgat ccgggagctg gactacgaga ccacacaggc ctaccagctc      540

acggtcaacg ccacagatca agacaagacc aggcctctgt ccaccctggc caacttggcc      600

atcatcatca cagatgtcca ggacatggac cccatcttca tcaacctgcc ttacagcacc      660

aacatctacg agcattctcc tccgggcacg acggtgcgca tcatcaccgc catagaccag      720

gataaaggac gtccccgggg cattggctac accatcgttt cagggaatac caacagcatc      780

tttgccctgg actacatcag cggagtgctg accttgaatg gcctgctgga ccgggagaac      840

cccctgtaca gccatggctt catcctgact gtgaagggca cggagctgaa cgatgaccgc      900

accccatctg acgctacagt caccacgacc ttcaatatcc tggttattga catcaatgac      960

aatgccccgg agttcaacag ctccgagtac agcgtggcca tcactgagct ggcacaggtc     1020

ggctttgccc ttccactctt catccaggtg gtggacaagg atgagaattt gggcctgaac     1080

agcatgtttg aggtgtactt ggtggggaac aactcccacc acttcatcat ctccccgacc     1140

tccgtccagg ggaaggcgga cattcgtatt cgggtggcca tcccactgga ctacgagacc     1200

gtggaccgct acgactttga tctctttgcc aatgagagtg tgcctgacca tgtgggctat     1260

gccaaggtga agatcactct catcaatgaa aatgacaacc ggcccatctt cagccagcca     1320

ctgtacaaca tcagcctgta cgagaacgtc accgtgggga cctctgtgct gacagtcctg     1380

gcaactgaca atgatgcagg cacctttggg gaagtcagct acttcttcag tgatgaccct     1440

gacaggttct cgctggacaa ggacacggga ctcatcatgc tgattgccag gctggactat     1500

gagctcatcc agcgcttcac cctgacgatc attgcccggg acgggggcgg cgaggagacc     1560

acaggccggg tcaggatcaa tgtgttggat gtcaacgaca acgtgcccac cttccagaag     1620

gatgcctacg tgggtgctct gcgggagaac gagccttctg tcacacagct ggtgcggctc     1680

cgggcaacag atgaagactc ccctcccaac aaccagatca cctacagcat tgtcagtgca     1740

tctgcctttg gcagctactt cgacatcagc ctgtacgagg gctatggagt gatcagcgtc     1800

agtcgccccc tggattatga acagatatcc aatgggctga tttatctgac ggtcatggcc     1860

atggatgctg gcaacccccc tctcaacagc accgtccctg tcaccatcga ggtgtttgat     1920

gagaatgaca accctcccac cttcagcaag cccgcctact tcgtctccgt ggtggagaac     1980

atcatggcag gagccacggt gctgttcctg aatgccacag acctggaccg ctcccgggag     2040

tacggccagg agtccatcat ctactccttg gaaggctcca cccagtttcg gatcaatgcc     2100

cgctcagggg aaatcaccac cacgtctctg cttgaccgag agaccaagtc tgaatacatc     2160

ctcatcgttc gcgcagtgga cgggggtgtg ggccacaacc agaaaactgg catcgccacc     2220

gtaaacatca ccctcctgga catcaacgac aaccacccca cgtggaagga cgcaccctac     2280

tacatcaacc tggtggagat gacccctcca gactctgacg tgaccacggt ggtggctgtt     2340

gacccagacc tgggggagaa tggcaccctg gtgtacagca tccagccacc caacaagttc     2400

tacagcctca acagcaccac gggcaagatc cgcaccaccc acgccatgct ggaccgggag     2460

aaccccgacc cccatgaggc cgagctgatg cgcaaaatcg tcgtctctgt tactgactgt     2520

ggcaggcccc ctctgaaagc caccagcagt gccacagtgt ttgtgaacct cttggatctc     2580

aatgacaatg accccacctt tcagaacctg ccttttgtgg ccgaggtgct tgaaggcatc     2640

ccggcggggg tctccatcta ccaagtggtg gccatcgacc tcgatgaggg cctgaacggc     2700

ctggtgtcct accgcatgcc ggtgggcatg ccccgcatgg acttcctcat caacagcagc     2760

agcggcgtgg tggtcaccac caccgagctg gaccgcgagc gcatcgcgga gtaccagctg     2820

cgggtggtgg ccagtgatgc aggcacgccc accaagagct ccaccagcac gctcaccatc     2880

catgtgctgg atgtgaacga cgagacgccc accttc                               2916


<210>  3323
<211>  1677
<212>  DNA
<213>  Homo Sapiens

<400>  3323
agctgggtct ggaaccagtt ctttgtcatt gaggaatatg ctggtccaga gcctgttctc       60

attggcaagc tgcactcgga tgttgaccgg ggagagggcc gcaccaagta cctgttgacc      120

ggggaggggg caggcaccgt atttgtgatt gatgaggcca caggcaatat tcatgttacc      180

aagagccttg accgggagga aaaggcgcaa tatgtgctac tggcccaagc cgtggaccga      240

gcctccaacc ggcccctgga gcccccatca gagttcatca tcaaagtgca agacatcaac      300

gacaatccac ccatttttcc ccttgggccc taccatgcca ccgtgcccga gatgtccaat      360

gtcgggacat cagtgatcca ggtgactgct cacgatgctg atgaccccag ctatgggaac      420

agtgccaagc tggtgtacac tgttctggat ggactgcctt tcttctctgt ggacccccag      480

actggagtgg tgcgtacagc catccccaac atggaccggg agacacagga ggagttcttg      540

gtggtgatcc aggccaagga catgggcggc cacatggggg ggctgtcagg cagcactacg      600

gtgactgtca cgctcagcga tgtcaacgac aaccccccca agttcccaca gagcctatac      660

cagttctccg tggtggagac agctggacct ggcacactgg tgggccggct ccgggcccag      720

gacccagacc tgggggacaa cgccctgatg gcatacagca tcctggatgg ggaggggtct      780

gaggccttca gcatcagcac agacttgcag ggtcgagacg ggctcctcac tgtccgcaag      840

cccctagact ttgagagcca gcgctcctac tccttccgtg tcgaggccac caacacgctc      900

attgacccag cctatctgcg gcgagggccc ttcaaggatg tggcctctgt gcgtgtggca      960

gtgcaagatg ccccagagcc acctgccttc acccaggctg cctaccacct gacagtgcct     1020

gagaacaagg ccccggggac cctggtaggc cagatctccg cggctgacct ggactcccct     1080

gccagcccaa tcagatactc catcctcccc cactcagatc cggagcgttg cttctctatc     1140

cagcccgagg aaggcaccat ccatacagca gcacccctgg atcgcgaggc tcgcgcctgg     1200

cacaacctca ctgtgctggc tacagagctc gacagttctg cacaggcctc gcgcgtgcaa     1260

gtggccatcc agaccctgga tgagaatgac aatgctcccc agctggctga gccctacgat     1320

acttttgtgt gtgactctgc agctcctggc cagctgattc aggtcatccg ggccctggac     1380

agggatgaag ttggcaacag tagccatgtc tcctttcaag gtcctctggg ccctgatgcc     1440

aactttactg tccaggacaa ccgagatggc tccgccagcc tgctgctgcc ctcccgccct     1500

gctccacccc gccatgcccc ctacttggtt cccatagaac tgtgggactg ggggcagccg     1560

gcgctgagca gcactgccac agtgactgtt agtgtgtgcc gctgccagcc tgacggctct     1620

gtggcatcct gctggcctga ggctcacctc tcagctgctg ggctcagcac cggcgcc        1677


<210>  3324
<211>  1782
<212>  DNA
<213>  Homo Sapiens

<400>  3324
attgacagtg ttcaacagga aacagatgat cttactaagc aaacaaagtg tcactataag       60

ttccaggaaa agatctacca gcctctacgg cgatccaaga gaagatgggt tatcaccacc      120

ttggagatgg aggaggaaga cccgggaccc tttcccaaac tcattggtga gctgttcaat      180

aatatgtctt ataacatgtc actaatgtat ctaatcagtg gacctggtgt ggatgaatat      240

ccagagattg gtttgttttc tctagaagat catgagaacg gaaggatata tgttcaccgc      300

cctgtcgatc gagaaatgac accatctttc acggtttatt ttgatgttgt ggagcgctca      360

acaggaaaaa ttgtggatac atccttgatt ttcaacatta ggatcagtga tgtgaatgat      420

catgcacccc agtttccaga gaaggaattt aacatcactg tgcaagaaaa ccaatctgca      480

gggcaaccta tttttcagat gttagcagtc gatttggatg aagaaaacac tccaaattct      540

caagtccttt acttcctcat ttctcaaaca ccattactga aagaaagtgg tttccgggtt      600

gatcgcctta gtggagaaat acgactctct ggctgcttag attatgagac cgctcctcag      660

tttacactgc taatcagagc cagggactgt ggagaaccgt cactgtcatc cacgaccacc      720

gttcacgtgg atgtgcaaga aggcaacaac cacaggcctg catttaccca ggagaactat      780

aaggttcaga ttcctgaagg ccgagccagc cagggcgtgt tgcgtctcct ggttcaagat      840

cgagattctc catttacatc agcttggaga gcaaaattca acatattgca tggcaatgaa      900

gaggggcatt ttgacatttc gactgaccct gagaccaacg aagggatatt aaatgttatc      960

aagcctttgg attatgagac tcgcccagcg caaagcctca tcattgtcgt ggagaatgag     1020

gagaggctcg tcttctgtga gagaggaaag cttcagccgc caaggaaggc agcagccagc     1080

gccactgtga gtgtgcaggt gacagacgcc aacgacccac cagcctttca cccccagagc     1140

ttcattgtca ataaagagga gggcgccagg cctgggaccc tgttgggaac ttttaatgcc     1200

atggatccag acagccagat aagatatgaa ctggttcatg acccagcaaa ttgggtcagc     1260

gtcgacaaaa actccggagt ggtcatcacc gtggagccaa ttgaccgaga atcccctcat     1320

gtaaataaca gtttttatgt aatcatcatt cacgctgttg atgatggctt cccaccgcag     1380

actgctacag ggaccctaat gctcttcctg tctgacatca atgacaacgt cccgactctc     1440

cggccacgtt cccgctacat ggaggtctgt gagtctgctg tgcatgagcc cctccacatc     1500

gaggcagagg atccggacct ggagccgttc tctgacccat ttacatttga attggacaat     1560

acctggggaa atgcggagga cacatggaag ttggggagaa attggggtca atcagttgaa     1620

cttttaacct tgagaagcct gccacgtggt aattacttgg tgccactctt cattggagac     1680

aaacagggac tttcccagaa gcaaactgtc catgtaagga tctgcccctg tgccagtggg     1740

ctcacatgtg tggagcttgc agatgcagaa gtggggcttc at                        1782


<210>  3325
<211>  1641
<212>  DNA
<213>  Homo Sapiens

<400>  3325
gattgggtgg ttgctccaat atctgtccct gaaaatggca agggtccctt cccccagaga       60

ctgaatcagc tcaagtctaa taaagataga gacaccaaga ttttctacag catcacgggg      120

ccgggggcag acagcccccc tgagggtgtc ttcgctgtag agaaggagac aggctggttg      180

ttgttgaata agccactgga ccgggaggag attgccaagt atgagctctt tggccacgct      240

gtgtcagaga atggtgcctc agtggaggac cccatgaaca tctccatcat agtgaccgac      300

cagaatgacc acaagcccaa gtttacccag gacaccttcc gagggagtgt cttagaggga      360

gtcctaccag gtacttctgt gatgcagatg acagccacag atgaggatga tgccatctac      420

acctacaatg gggtggttgc ttactccatc catagccaag aaccaaagga cccacacgac      480

ctcatgttca caattcaccg gagcacaggc accatcagcg tcatctccag tggcctggac      540

cgggaaaaag tccctgagta cacactgacc atccaggcca cagacatgga tggggacggc      600

tccaccacca cggcagtggc agtagtggag atccttgatg ccaatgacaa tgctcccatg      660

tttgaccccc agaagtacga ggcccatgtg cctgagaatg cagtgggcca tgaggtgcag      720

aggctgacgg tcactgatct ggacgccccc aactcaccag cgtggcgtgc cacctacctt      780

atcatgggcg gtgacgacgg ggaccatttt accatcacca cccaccctga gagcaaccag      840

ggcatcctga caaccaggaa gggtttggat tttgaggcca aaaaccagca caccctgtac      900

gttgaagtga ccaacgaggc cccttttgtg ctgaagctcc caacctccac agccaccata      960

gtggtccacg tggaggatgt gaatgaggca cctgtgtttg tcccaccctc caaagtcgtt     1020

gaggtccagg agggcatccc cactggggag cctgtgtgtg tctacactgc agaagaccct     1080

gacaaggaga atcaaaagat cagctaccgc atcctgagag acccagcagg gtggctagcc     1140

atggacccag acagtgggca ggtcacagct gtgggcaccc tcgaccgtga ggatgagcag     1200

tttgtgagga acaacatcta tgaagtcatg gtcttggcca tggacaatgg aagccctccc     1260

accactggca cgggaaccct tctgctaaca ctgattgatg tcaacgacca tggcccagtc     1320

cctgagcccc gtcagatcac catctgcaac caaagccctg tgcgccaggt gctgaacatc     1380

acggacaagg acctgtctcc ccacacctcc cctttccagg cccagctcac agatgactca     1440

gacatctact ggacggcaga ggtcaacgag gaaggtgaca cagtggtctt gtccctgaag     1500

aagttcctga agcaggatac atatgacgtg cacctttctc tgtctgacca tggcaacaaa     1560

gagcagctga cggtgatcag ggccactgtg tgcgactgcc atggccatgt cgaaacctgc     1620

cctggaccct ggaaaggagg t                                               1641


<210>  3326
<211>  1695
<212>  DNA
<213>  Homo Sapiens

<400>  3326
gactgggtca tcccgcccat caacgtgccc gagaactcgc gcgggccctt cccgcagcag       60

ctcgtgagga tccggtccga caaagacaat gacatcccca tccggtacag catcacggga      120

gtgggcgccg accagccccc catggaggtc ttcagcattg actccatgtc cggccggatg      180

tacgtcacaa ggcccatgga ccgggaggag cacgcctctt accacctccg agcccacgct      240

gtggacatga atggcaacaa ggtggagaac cccatcgacc tgtacatcta cgtcatcgac      300

atgaatgaca accgccctga gttcatcaac caggtctaca acggctccgt ggacgagggc      360

tccaagccag gcacctacgt gatgaccgtc acggccaacg atgctgacga cagcaccacg      420

gccaacggga tggtgcggta ccggatcgtg acccagaccc cacagagccc gtcccagaat      480

atgttcacca tcaacagcga gactggagat atcgtcacag tggcggctgg cctggaccga      540

gagaaagttc agcagtacac agtcatcgtt caggccacag atatggaagg aaatctcaac      600

tatggcctct caaacacagc cacagccatc atcacggtga cagatgtgaa tgacaacccg      660

ccagaattta ccgccagcac gtttgcaggg gaggtccccg aaaaccgcgt ggagaccgtg      720

gtcgcaaacc tcacggtgat ggaccgagat cagccccact ctccaaactg gaatgccgtt      780

taccgcatca tcagtgggga tccatccggg cacttcagcg tccgcacaga tcccgtaacc      840

aacgagggca tggtcaccgt ggtgaaggca gtcgactacg agctcaacag agctttcatg      900

ctgacagtga tggtgtccaa ccaggcgccc ctggccagcg gaatccagat gtccttccag      960

tccacggcag gggtgaccat ctccatcatg gacatcaacg aggctcccta cttcccctca     1020

aaccacaagc tgatccgcct ggaggagggc gtgccccccg gcaccgtgct gaccacgttt     1080

tcagctgtgg accctgaccg gttcatgcag caggctgtga gatactcaaa gctgtcagac     1140

ccagcgagct ggctgcacat caatgccacc aacggccaga tcaccacggc ggcagtgctg     1200

gaccgtgagt ccctctacac caaaaacaac gtctacgagg ccaccttcct ggcagctgac     1260

aatgggatac ccccggccag cggcaccggg accctccaga tctatctcat tgacatcaac     1320

gacaacgccc ctgagctgct gcccaaggag gcgcagatct gcgagaagcc caacctgaac     1380

gccatcaaca tcacggcggc cgacgctgac gtcgacccca acatcggccc ctacgtcttc     1440

gagctgccct ttgtcccggc ggccgtgcgg aagaactgga ccatcacccg cctgaacggt     1500

gactatgccc aactcagctt gcgcatcctg tacctggagg ccgggatgta tgacgtcccc     1560

atcatcgtca cagactctgg aaaccctccc ctgtccaaca cgtccatcat caaagtcaag     1620

gtgtgcccat gtgatgacaa cggggactgc accaccattg gcgcagtggc agcggctggt     1680

ctgggcaccg gtgcc                                                      1695


<210>  3327
<211>  1290
<212>  DNA
<213>  Homo Sapiens

<400>  3327
gattggattt ggaaccagat gcacattgat gaagagaaaa acacctcact tccccatcat       60

gtaggcaaga tcaagtcaag cgtgagtcgc aagaatgcca agtacctgct caaaggagaa      120

tatgtgggca aggtcttccg ggtcgatgca gagacaggag acgtgttcgc cattgagagg      180

ctggaccggg agaatatctc agagtaccac ctcactgctg tcattgtgga caaggacact      240

ggtgaaaacc tggagactcc ttccagcttc accatcaaag ttcatgacgt gaacgacaac      300

tggcctgtgt tcacgcatcg gttgttcaat gcgtccgtgc ctgagtcgtc ggctgtgggg      360

acctcagtca tctctgtgac agcagtggat gcagacgacc ccactgtggg agaccacgcc      420

tctgtcatgt accaaatcct gaaggggaaa gagtattttg ccatcgataa ttctggacgt      480

attatcacaa taacgaaaag cttggaccga gagaagcagg ccaggtatga gatcgtggtg      540

gaagcgcgag atgcccaggg cctccggggg gactcgggca cggccaccgt gctggtcact      600

ctgcaagaca tcaatgacaa cttccccttc ttcacccaga ccaagtacac atttgtcgtg      660

cctgaagaca cccgtgtggg cacctctgtg ggctctctgt ttgttgagga cccagatgag      720

ccccagaacc ggatgaccaa gtacagcatc ttgcggggcg actaccagga cgctttcacc      780

attgagacaa accccgccca caacgagggc atcatcaagc ccatgaagcc tctggattat      840

gaatacatcc agcaatacag cttcatcgtc gaggccacag accccaccat cgacctccga      900

tacatgagcc ctcccgcggg aaacagagcc caggtcatta tcaacatcac agatgtggac      960

gagcccccca ttttccagct ggtcctgcag atctccgcaa tagacaagga cataacacca     1020

cgaaacgtga agttcaaatt caccttgaat actgagaaca actttaccct cacggataat     1080

cacgataaca cggccaacat cacagtcaag tatgggcagt ttgaccggga gcataccaag     1140

gtccacttcc tacccgtggt catctcagac aatgggatgc caagtcgcac gggcaccagc     1200

acgctgaccg tggccgtgtg caagtgcaac gagcagggcg agttcacctt ctgcgaggat     1260

atggccgccc aggtggacgt gagcatccag                                      1290


<210>  3328
<211>  1686
<212>  DNA
<213>  Homo Sapiens

<400>  3328
agctggatgt ggaatcagtt ctttctcctg gaggaataca caggatccga ttatcagtat       60

gtgggcaagt tacattcaga ccaggataga ggagatggat cacttaaata tatcctttca      120

ggagatggag caggagatct cttcattatt aatgaaaaca caggcgacat acaggccacc      180

aagaggctgg acagggaaga aaaacccgtt tacatccttc gagctcaagc tataaacaga      240

aggacaggga gacccgtgga gcccgagtct gaattcatca tcaagatcca tgacatcaat      300

gacaatgaac caatattcac caaggaggtt tacacagcca ctgtccctga aatgtctgat      360

gtcggtacat ttgttgtcca agtcactgcg acggatgcag atgatccaac atatgggaac      420

agtgctaaag ttgtctacag tattctacag ggacagccct atttttcagt tgaatcagaa      480

acaggtatta tcaagacagc tttgctcaac atggatcgag aaaacaggga gcagtaccaa      540

gtggtgattc aagccaagga tatgggcggc cagatgggag gattatctgg gaccaccacc      600

gtgaacatca cactgactga tgtcaacgac aaccctcccc gattccccca gagtacatac      660

cagtttaaaa ctcctgaatc ttctccaccg gggacaccaa ttggcagaat caaagccagc      720

gatgctgatg tgggagaaaa tgctgaaatt gagtacagca tcacagacgg tgaggggctg      780

gatatgtttg atgtcatcac cgaccaggaa acccaggaag ggattataac tgtcaaaaag      840

ctcttggact ttgaaaagaa gaaagtgtat acccttaaag tggaagcctc caatccttat      900

gttgagccac gatttctcta cttggggcct ttcaaagatt cagccacggt tagaattgtg      960

gtggaggatg tagatgagcc acctgtcttc agcaaactgg cctacatctt acaaataaga     1020

gaagatgctc agataaacac cacaataggc tccgtcacag cccaagatcc agatgctgcc     1080

aggaatcctg tcaagtactc tgtagatcga cacacagata tggacagaat attcaacatt     1140

gattctggaa atggttcgat ttttacatcg aaacttcttg accgagaaac actgctatgg     1200

cacaacatta cagtgatagc aacagagatc aataatccaa agcaaagtag tcgagtacct     1260

ctatatatta aagttctaga tgtcaatgac aacgccccag aatttgctga gttctatgaa     1320

acttttgtct gtgaaaaagc aaaggcagat cagttgattc agaccttgca tgctgttgac     1380

aaggatgacc cttatagtgg gcaccaattt tcgttttcct tggcccctga agcagccagt     1440

ggctcaaact ttaccattca agacaacaaa gacaacacgg cgggaatctt aactcggaaa     1500

aatggctata atagacacga gatgagcacc tatctcttgc ctgtggtcat ttcagacaac     1560

gactacccag ttcaaagcag cactgggaca gtgactgtcc gggtctgtgc atgtgaccac     1620

cacgggaaca tgcaatcctg ccacgcggag gcgctcatcc accccacggg actgagcacg     1680

ggggct                                                                1686


<210>  3329
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  3329
agctgggtgt ggaatcagtt ctttgtgctg gaggaataca tgggttcaga ccccctctat       60

gtaggaaagc ttcactctga tgttgataaa ggagatggtt ccatcaaata catcttgtca      120

ggcgaagggg caagttccat tttcattatt gatgagaaca ctggggatat tcatgccacc      180

aagagactgg atcgtgagga gcaggcctac tacacgctcc gagctcaagc gctggatagg      240

ctcaccaacg aacccgtgga gcccgagtcg gagtttgtca tcaaaattca ggatatcaac      300

gacaatgaac ccaaattttt ggatggccca tacacggcag gagttcccga aatgtctccc      360

gtggggacct cagtggtaca agtgacagcg acggatgctg atgatcctac atatggcaac      420

agtgccagag tggtctacag tattctgcaa ggacagccgt acttctcagt ggagccaaag      480

acaggagtca tcaagactgc ccttccaaac atggatagag aggctaaaga ccagtatttg      540

cttgttattc aggcaaagga tatggttggt caaaatggag gactgtcagg aactacatca      600

gtcactgtga ccctaactga tgtcaacgat aatccacctc gctttcctcg aaggtcttat      660

caatataacg tcccagagtc attacctgta gcctcagttg tggccagaat taaagctgct      720

gatgcagata ttggagctaa tgctgaaatg gagtacaaga ttgtggatgg tgatggtttg      780

ggcattttta agatttctgt tgacaaagaa acccaggaag gaatcattac tatacagaag      840

gagctggatt ttgaagccaa aacaagttac acgctacgga tagaagctgc aaataaagat      900

gccgaccctc gctttctgag cttgggtccg ttcagtgaca cgacaactgt gaagataatt      960

gtggaagatg tagatgagcc ccctgtgttc tcttcaccct tgtaccctat ggaggtgtcg     1020

gaagctaccc aggttgggaa tatcattggc actgtagcag ctcatgaccc agattcttcc     1080

aatagccctg tgaggtactc aattgacaga aacacagact tggagagata cttcaatatt     1140

gatgccaaca gtggggtcat cacaactgcc aagtctttgg atcgagagac aaatgctatt     1200

cacaatatca cagtccttgc aatggagagc cagaatccat ctcaagtagg aagaggctat     1260

gtggccatca ctatacttga catcaatgat aacgcccctg aatttgccat ggactatgag     1320

accaccgtct gtgaaaatgc ccagccgggg caggttatcc agaaaatcag tgctgtggat     1380

aaagatgagc catccaatgg acaccagttt tacttcagct taacaacgga tgcaacaaat     1440

aaccacaact tttcattgaa agataacaaa gacaacacag cctcaatact gaccaggaga     1500

aacggcttcc ggagacagga acaatcagtt tactatctgc caattttcat tgtggacagt     1560

ggatctccct cacttagcag caccagcacc ctcaccatcc gcgtgtgtga ctgtgatgct     1620

gacggcgtag cccagacctg caatgcagag gcctatgtcc tacctgctgg cctcagtaca     1680


<210>  3330
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  3330
ggctgggttt ggaatcaaat gtttgtcctg gaagagtttt ctggacctga accgattctt       60

gttggccggc tacacacaga cctggatcct gggagcaaaa aaatcaagta tatcctatca      120

ggtgatggag ctgggaccat atttcaaata aatgatgtaa ctggagatat ccatgctata      180

aaaagacttg accgggagga aaaggctgag tataccctaa cagctcaagc agtggactgg      240

gagacaagca aacctctgga gcctccttct gaatttatta ttaaagttca agacatcaat      300

gacaatgcac cagagtttct taatggaccc tatcatgcta ctgtgccaga aatgtccatt      360

ttgggtacat ctgtcactaa cgtcactgcg accgacgctg atgacccagt ttatggaaac      420

agtgcaaagt tggtttatag tatattggaa gggcagcctt atttttccat tgagcctgaa      480

acagctatta taaaaactgc ccttcccaac atggacagag aagccaagga ggagtacctg      540

gttgttatcc aagccaaaga tatgggtgga cactctggtg gcctgtctgg gaccacgaca      600

cttacagtga ctcttactga tgttaatgac aatcctccaa aatttgcaca gagcctgtat      660

cacttctcag taccggaaga tgtggttctt ggcactgcaa taggaagggt gaaggccaat      720

gatcaggata ttggtgaaaa tgcacagtca tcatatgata tcatcgatgg agatggaaca      780

gcactttttg aaatcacttc tgatgcccag gcccaggatg gcattataag gctaagaaaa      840

cctctggact ttgagaccaa aaaatcctat acgctaaagg tagaggcagc caatgtccat      900

attgacccac gcttcagtgg cagggggccc tttaaagaca cggcgacagt caaaatcgtg      960

gttgaagatg ctgatgagcc tccggtcttc tcttcaccga cttacctact tgaagttcat     1020

gaaaatgctg ctctaaactc cgtgattggg caagtgactg ctcgtgaccc tgatatcact     1080

tccagtccta taaggttttc catcgaccgg cacactgacc tggagaggca gttcaacatt     1140

aatgcagacg atgggaagat aacgctggca acaccacttg acagagaatt aagtgtatgg     1200

cacaacataa caatcattgc tactgaaatt aggaaccaca gtcagatatc acgagtacct     1260

gttgctatta aagtgctgga tgtcaatgac aacgcccctg aattcgcatc cgaatatgag     1320

gcatttttat gtgaaaatgg aaaacccggc caagtcattc aaactgttag cgccatggac     1380

aaagatgatc ccaaaaacgg acattatttc ttatacagtc tccttccaga aatggtcaac     1440

aatccgaatt tcaccatcaa gaaaaatgaa gataattccc tcagtatttt ggcaaagcat     1500

aatggattca accgccagaa gcaagaagtc tatcttttac caatcataat cagtgatagt     1560

ggaaatcctc cactgagcag cactagcacc ttgacaatca gggtctgtgg ctgcagcaat     1620

gacggtgtcg tccagtcttg caatgtcgaa gcttatgtcc ttccaattgg actcagtatg     1680


<210>  3331
<211>  1686
<212>  DNA
<213>  Homo Sapiens

<400>  3331
ggctggatgt ggaatcagtt cttcttattg gaagagtaca caggtactga cacacaatat       60

gtaggcaagc ttcacactga ccaagataaa ggagatggaa atttaaaata catactaaca      120

ggagatgggg ctggcagtct atttgttata gatgaaaata caggagacat tcatgctgca      180

aagaaactag acagagaaga aaaatctctg tacattcttc gtgccaaggc tatagacaga      240

aaaactgggc ggcaggtgga accggaatcg gaatttatca ttaaaataca tgatatcaat      300

gacaatgagc caaaatttac aaaagactta tacactgcca gtgttcctga aatgtctgga      360

gtcggtacat ctgttataca agtaactgca acagatgcag atgacgccaa ctatggaaat      420

agtgccaaag tggtctatag catattgcaa ggacagccat atttttcagt ggacccagaa      480

tcaggcataa taaaaactgc attaccagac atgagcagag aaaatagaga gcagtaccag      540

gttgttatac aggccaaaga catgggtggc cagatgggag gcctttctgg aaccaccaca      600

gtgaacatca cgctgacaga tgtcaacaac aaccctcctc gatttcccca gagtacgtat      660

caatttaatt ctcctgagtc tgtacctctt ggaactcatc ttggaaggat aaaagccaat      720

gaccctgacg tgggggaaaa tgcagaaatg gagtatagca ttgctgaagg agatggtgca      780

gacatgttcg atgtcatcac tgacaaggat acacaggaag ggattataac tgtcaaacag      840

aatttagatt ttgaaaatca aatgctctat actttaagag tggatgcaag taacactcac      900

cctgatccac gattcttaca cctgggacct ttcaaagata cagctgtggt caaaatatct      960

gtggaagata tagatgagcc tcctgtgttc actaaagtct cttacttgat agaagtagat     1020

gaagatgtaa aggagggcag tatcattgga caggttacag catacgatcc agatgccagg     1080

aacaatttaa taaagtactc tgttgatcgg catactgata tggaccgtat ttttggtatt     1140

cactcagaaa atggttctat tttcactttg aaagcccttg accgggaatc atctccttgg     1200

cataacatca ctgttacagc cacagaaata aataacccaa aacaaagtag ccacatccct     1260

gtcttcatca gaattctaga tataaatgac catgctccgg aatttgccat gtattatgaa     1320

acatttgttt gtgaaaatgc aaaacctggg cagttgattc agactgtcag tgtcatggat     1380

aaggatgacc ctccccgagg tcacaaattc ttttttgaac cagtgccaga atttactctc     1440

aatccgaatt tcaccattgt agataataaa gataatacag caggaatcat gactcggaaa     1500

gatggctaca gtcgcaacaa aatgagcacc tacttattgc cgattttaat ctttgacaac     1560

gattatccaa ttcaaagcag cactggtaca ctcactatcc gtgtgtgtgc ctgcgataat     1620

caaggaaaca tgcaatcctg caccgcagaa gccctgatcc tttcagccgg cctgagcacg     1680

ggagct                                                                1686


<210>  3332
<211>  2814
<212>  DNA
<213>  Homo Sapiens

<400>  3332
gacttggcac cttattttac ttctgagccg ctctctgctg tccagaaact tggtggacct       60

gtagtactgc attgttctgc tcaacctgtg accactcgta tctcatggct gcataacgga      120

aaaacattgg atggaaacct ggaacatatt aagattcatc aggggactct gacaattctt      180

tctctcaact cctctctttt gggttactac cagtgccttg ccaacaatag catcggtgcc      240

attgtgagtg gccctgcgac agtatctgtg gcagttcttg gtgattttgg ttcatccaca      300

aagcatgtta ttacagcaga agaaaaaagt gctggtttca ttggctgcag ggtaccggag      360

agtaacccca aagctgaggt gcgctataaa atccggggaa aatggctgga acattccaca      420

gagaattact taatccttcc atcaggaaat cttcagattt tgaatgtatc cttagaggac      480

aagggatcat acaaatgtgc agcttataat cctgtcacac atcaattaaa agttgaacct      540

attggccgaa agctccttgt gagtcgtcct tcttcagatg atgttcacat tcttcacccc      600

acccattcac aggcattagc tgttctttct cgtagccctg taaccttgga gtgtgtggtg      660

agtggggtcc cggctcctca agtgtattgg ctaaaggacg ggcaggacat tgcaccagaa      720

agcaactgga gaaggttgta ttctcatctt gccactgata gcgttgaccc ggcggactcc      780

ggaaactatt cctgcatggc gggaaacaag tctggagatg taaaatatgt gacttacatg      840

gttaatgtac ttgaacatgc ttccatttct aaaggactac aggatcagat agtgtctctg      900

ggtgccacag tacactttac ctgcgacgtt catgggaacc cagcccccaa ctgtacctgg      960

tttcacaatg cacagcctat tcatccttct gcacgacatc taactgcagg aaacggactg     1020

aaaatcagtg gggttactgt ggaagatgtt gggatgtatc agtgtgtagc agataatggg     1080

attggattta tgcactctac tggaagactt gaaattgaaa atgacggtgg attcaagcca     1140

gttataatta cggcaccagt aagtgcaaag gttgcagacg gagactttgt tactctgtcc     1200

tgcaatgcca gtgggctgcc ggttccggtc attcgttggt atgacagcca tggattgata     1260

accagccatc catctcaagt cctgagatcg aaatcccgaa aatcacagtt atcaagacct     1320

gagggcttga acctggagcc tgtgtacttc gtcctgtccc aagctggtgc aagctctctc     1380

catattcagg ctgtgactca ggaacatgcg gggaaataca tctgcgaagc tgcaaatgaa     1440

catggtacca cacaggcaga agcatctctc atggttgttc cttttgaaac aaatacaaaa     1500

gcagagacag tcacacttcc tgatgctgct cagaatgatg acagaagtaa gagagatggt     1560

tcagaaactg ggttactgag ctcatttccg gtgaaggtcc atcccagtgc agtggaatca     1620

gcaccagaga aaaacgccag cggcatctct gttcctgatg cccccatcat actgagcccc     1680

ccacagaccc acacaccaga cacgtacaac ctggtgtgga gggcaggcaa ggatggtggg     1740

ctgcccatca atgcttactt tgtgaagtat cgaaagctgg atgatggggt tggcatgctg     1800

ggaagctggc acacggttcg agtcccagga agtgaaaatg agctccattt agctgagctg     1860

gagccatcta gtctttatga agtcttgatg gtagcaagaa gcgcagcagg tgaaggccaa     1920

cctgccatgc ttaccttccg aaccagcaaa gaaaaaacag cgtcatcaaa aaacacccag     1980

gcatcctctc cacccgtggg catccctaag tatcccgttg tttcagaggc tgcaaacaac     2040

aattttggag tggtacttac agattcctct aggcacagtg gagttccaga ggcaccagat     2100

cggcctacca tctccactgc atcagagaca tcagtctatg tcacttggat tcctcgggca     2160

aacgggggtt ctccaatcac tgccttcaaa gtcgaatata aacggatgag gaccagcaat     2220

tggctggtgg cagctgaaga catccctcct tccaaacttt cagtggaagt tcgtagttta     2280

gaaccaggtt caacatacaa atttagggtc attgccatca accattatgg tgagagtttt     2340

cggagttcag catctcgtcc ttatcaagtg gttgggttcc ccaatcgctt ttccagccgt     2400

ccaataactg gacctcacat tgcatacaca gaggctgtca gcgatactca gatcatgcta     2460

aagtggacgt acattccatc aagtaacaat aacactccca ttcaaggatt ttatatctat     2520

taccgaccaa cagatagtga caatgacagt gattacaaga gggatgttgt agaaggttca     2580

aagcagtggc acatgattgg ccacctgcag ccagaaacct cctatgacat taaaatgcaa     2640

tgcttcaatg aaggaggaga aagtgaattt agcaatgtga tgatctgcga gactaaagtg     2700

aaacgtgttc ctggagcttc tgaatatcct gtcaaagact tgagtacccc tccaaattct     2760

ttgggaagtg gaggaaatgt ggggcctgca accagccctg ccagaagcag tgac           2814


<210>  3333
<211>  960
<212>  DNA
<213>  Homo Sapiens

<400>  3333
cagaagctct ctaagcacaa gacaccagca cagccacagc tcaaagcggc caactgctgt       60

gaggaggtga aggagctcaa ggcccaagtt gccaacctta gcagcctgct gagtgaactg      120

aacaagaagc aggagaggga ctgggtcagc gtggtcatgc aggtgatgga gctggagagc      180

aacagcaagc gcatggagtc gcggctcaca gatgctgaga gcaagtactc cgagatgaac      240

aaccaaattg acatcatgca gctgcaggca gcacagacgg tcactcagac ctccgcagat      300

gccatctacg actgctcttc cctctaccag aagaactacc gcatctctgg agtgtataag      360

cttcctcctg atgacttcct gggcagccct gaactggagg tgttctgtga catggagact      420

tcaggcggag gctggaccat catccagaga cgaaaaagtg gccttgtctc cttctaccgg      480

gactggaagc agtacaagca gggctttggc agcatccgtg gggacttctg gctggggaac      540

gaacacatcc accggctctc cagacagcca acccggctgc gtgtagagat ggaggactgg      600

gagggcaacc tgcgctacgc tgagtatagc cactttgttt tgggcaatga actcaacagc      660

tatcgcctct tcctggggaa ctacactggc aatgtgggga acgacgccct ccagtatcat      720

aacaacacag ccttcagcac caaggacaag gacaatgaca actgcttgga caagtgtgca      780

cagctccgca aaggtggcta ctggtacaac tgctgcacag actccaacct caatggagtg      840

tactaccgcc tgggtgagca caataagcac ctggatggca tcacctggta tggctggcat      900

ggatctacct actccctcaa acgggtggag atgaaaatcc gcccagaaga cttcaagcct      960


<210>  3334
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  3334
cagctcacta ctgaatccat gccattcaat gttgcagagg ggaaggaggt tcttctcctt       60

gtccacaatc tgccccagca actttttggc tacagctggt acaaagggga aagagtggat      120

ggcaaccgtc aaattgtagg atatgcaata ggaactcaac aagctacccc agggcccgca      180

aacagcggtc gagagacaat ataccccaat gcatccctgc tgatccagaa cgtcacccag      240

aatgacacag gattctacac cctacaagtc ataaagtcag atcttgtgaa tgaagaagca      300

actggacagt tccatgtata cccggagctg cccaagccct ccatctccag caacaactcc      360

aaccctgtgg aggacaagga tgctgtggcc ttcacctgtg aacctgagac tcaggacaca      420

acctacctgt ggtggataaa caatcagagc ctcccggtca gtcccaggct gcagctgtcc      480

aatggcaaca ggaccctcac tctactcagt gtcacaagga atgacacagg accctatgag      540

tgtgaaatac agaacccagt gagtgcgaac cgcagtgacc cagtcacctt gaatgtcacc      600

tatggcccgg acacccccac catttcccct tcagacacct attaccgtcc aggggcaaac      660

ctcagcctct cctgctatgc agcctctaac ccacctgcac agtactcctg gcttatcaat      720

ggaacattcc agcaaagcac acaagagctc tttatcccta acatcactgt gaataatagt      780

ggatcctata cctgccacgc caataactca gtcactggct gcaacaggac cacagtcaag      840

acgatcatag tcactgagct aagtccagta gtagcaaagc cccaaatcaa agccagcaag      900

accacagtca caggagataa ggactctgtg aacctgacct gctccacaaa tgacactgga      960

atctccatcc gttggttctt caaaaaccag agtctcccgt cctcggagag gatgaagctg     1020

tcccagggca acaccaccct cagcataaac cctgtcaaga gggaggatgc tgggacgtat     1080

tggtgtgagg tcttcaaccc aatcagtaag aaccaaagcg accccatcat gctgaacgta     1140

aactataatg ctctaccaca agaaaatggc ctctcacctg gg                        1182


<210>  3335
<211>  1215
<212>  DNA
<213>  Homo Sapiens

<400>  3335
gagatctcta tcaccctgga gcctgcccag ccgagcgaag gggacaacgt cacgctggtc       60

gtccatgggc tttcggggga actgctcgcc tacagctggt atgcggggcc cacactcagc      120

gtgtcatacc tggtggccag ctacatcgtg agcacaggcg atgagactcc tggcccggcc      180

cacacggggc gggaggctgt gcgccccgat ggcagcctgg acatccaggg catcctgccc      240

cggcactcag gcacctacat cctgcagacc ttcaacaggc agttgcagac cgaggtgggc      300

tacggacacg tgcaggtcca tgagatcctg gcccagccca cagtcttggc caacagcaca      360

gcgctggtgg aacgtcgaga caccctgcgc cttatgtgca gcagccccag ccccaccgcc      420

gaggtccgct ggttcttcaa cggtggggcc ctgcccgtcg ctctccgcct gggcctgtcc      480

cctgacggcc gggtgctggc caggcatggc atccgccggg aggaggccgg cgcctatcag      540

tgtgaggtgt ggaacccggt cagtgtcagc cgcagcgagc ccatcaacct gaccgtgtac      600

tttggcccag agcgtgtggc catcctccag gattccacca cccgcacagg ctgcaccatc      660

aaagttgact tcaacacgtc cctcaccctg tggtgcgtgt ccaggtcctg cccagagccc      720

gagtatgtgt ggaccttcaa cgggcaggcc ctaaagaacg gccaagacca cctcaacatc      780

agcagcatga cagccgccca ggaggggacg tacacatgta ttgcgaagaa caccaagacc      840

ctgctatctg gatctgcctc agtcgtggtc aagctctctg ctgcagcagt tgccacgatg      900

atcgtgcccg tgcccaccaa gccaacggag ggccaggacg taacactgac cgtgcagggc      960

taccccaagg acctgctggt ctacgcctgg taccgcgggc ctgcctccga gcccaaccgg     1020

ctgctcagcc agctgccgtc aggaacctgg attgcaggcc ccgcgcacac aggccgggag     1080

gtgggcttcc ccaactgctc gctgttggtg cagaagctga acctcacaga cactggccgc     1140

tacacactca agaccgtcac agtgcagggc aagactgaga cactggaagt ggagctgcag     1200

gtggcccccc tgggg                                                      1215


<210>  3336
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  3336
cagattttta tcacccaaac cctaggtatt aagggttata ggacagtcgt cgcgttggat       60

aaggttccag aggacgtaca agaatactcc tggtattggg gggctaacga ctctgcgggt      120

aatatgatca tctcacacaa gcctccgagc gcccagcaac cgggacccat gtatacaggt      180

agagagcgtg taaataggga aggttcacta ctaataagac caactgcatt aaatgatacc      240

gggaactata ccgtgcgtgt tgtagccgga aacgaaacgc agcgtgccac aggttggctg      300

gaggtattgg aattaggaag caatctgggg ataagtgtga acgcttcatc cttagtagaa      360

aatatggact ctgtagctgc cgattgtcta acgaatgtga ccaatataac ctggtatgta      420

aatgacgtgc ccacttcttc ctctgacagg atgacaatat cacctgacgg gaagacctta      480

gtaatattga gagtttctcg ttatgaccgt accatacagt gcatgataga gagctttccc      540

gagatattcc aaaggagtga gcgtatttca ttaacggttg cttatggccc cgactacgtg      600

ctattgagga gtaatcccga tgactttaac gggattgtga ctgcggaaat cgggagccaa      660

gtagaaatgg aatgtatctg ttacagcttc cttgatttaa aatatcattg gattcataac      720

ggtagcctat tgaattttag cgacgcaaag atgaaccttt cttcattagc gtgggaacaa      780

atgggccgtt acagatgcac cgtagaaaat ccagtaacac agttgataat gtatatggat      840

gttaggatac aggccccgca tgaagacctt acatgttgcc cacagaggtt tctgcatctt      900

aggattcacg gggacgttcc tcaccatgcc gacagcgctg gatggaggtt gcacctgtgg      960

tcacccgacc cttgcagcga tcaaccacta ctaaatcaag ataaaagcgg cagtatgtcc     1020

gtccacccaa gaccggagga caaaacgaga agggcttctc gt                        1062


<210>  3337
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  3337
gcactttaca ttcaaaaaat tccagagcaa cctcagaaaa atcaagacct tcttctgtca       60

gtacagggtg tgccggatac gtttcaggac ttcaattggt atcttgggga ggagacatac      120

ggtggaacta ggttgtttac atacatacct ggtattcaaa gacctcagag ggacggaagt      180

gccatgggac agagagacat cgtgggcttc cctaatggat ctatgttgct acgtcgtgcc      240

cagccaaccg atagcggcac ttatcaggtt gcaataacta taaattctga atggactatg      300

aaagccaaaa cggaagtgca ggttgctgaa aaaaacaaag agctgccctc aacgcacctt      360

cccacaaacg ccgga                                                       375


<210>  3338
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3338
cagttgactc ttaacgcaaa cccgttagac gccacacaga gcgaggatgt tgttctacca       60

gtttttggga caccgagaac gccccaaatt catgggagaa gccgtgagct tgccaagcca      120

agcattgctg tatcacctgg gactgcaatc gagcagaagg atatggtaac attctactgc      180

accacgaaag atgtaaacat caccatccac tgggtctcca ataatctttc aattgtgttc      240

catgagagaa tgcaactatc taaggatgga aagatcctga cgatattgat tgtgcaacgt      300

gaagattctg gcacatatca atgtgaagct agggatgcct tgttaagtca gcgtagcgat      360

cccattttcc ttgacgtaaa atacggccca gaccccgttg aaataaaact agagtctggt      420

gtcgcgtcag gtgaggtagt cgaggtcatg gaaggaagct ctatgacttt cctagccgag      480

acgaaaagtc atcctccgtg tgcatacact tggtttcttc ttgacagtat cttaagtcat      540

acaaccagaa cgttcacaat acatgctgtc agtagagagc atgaagggtt gtatcgttgt      600

ctagtgtcta atagtgctac ccatttatca tcattaggca ctctaaaagt tcgtgtactg      660

gaaacgttaa caatgccaca agtcgttcca tccagtctaa acctggtcga aaacgctagg      720

agtgtcgacc ttacttgcca aaccgtaaat cagtcagtca acgtgcagtg gttcttgagt      780

gggcaaccat tactgcctag tgaacattta cagttaagtg ctgataacag aacattaatc      840

atacacggct tgcaaagaaa tgacaccgga ccctacgcgt gtgaggtctg gaactggggc      900

agcagagcaa ggtcagaacc cttagagctg acaattaatt atggtcctga ccaagtgcac      960

attactaggg agtccgcatc agaaatgatc agtaccatag aggctgaatt aaatagctct     1020

ctaacgctgc agtgttgggc agagtccaaa ccgggtgcgg aatatcgttg gaccctggag     1080

cattccacgg gcgaacacct tggcgaacag ttgattattc gtgcattaac ttgggagcac     1140

gatggcatct ataattgtac ggcatccaat agtcttacag ggctggcgag atcaacatca     1200

gtgcttgtaa aggttgtagg tccacagtct agtagcctta gcagcggcgc gatagccggg     1260


<210>  3339
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  3339
tggctcttta ttgcatcagc gccctttgaa gttgctgaag gggagaatgt tcatctctct       60

gtggtttatc tgcccgagaa tctttacagc tatggctggt acaaagggaa aacggtggag      120

cccaaccagc taatcgcagc atatgtaata gacactcacg ttaggactcc agggcctgca      180

tacagcggtc gagagacaat atcacccagt ggagatctgc atttccagaa cgtcacccta      240

gaggacacgg gatactacaa cctacaagtc acatacagaa attctcagat tgaacaggca      300

tctcaccatc tccgtgtata cgagtcagtg gctcagccct ccatccaagc cagcagcacc      360

acagtcacag agaagggctc cgtggtcctg acctgccaca caaataacac tggaacctct      420

ttccagtgga ttttcaacaa ccagcgtctg caggtcacga agaggatgaa gctgtcctgg      480

tttaaccatg tgctcaccat agaccccatc aggcaggagg acgctgggga gtatcagtgt      540

gaggtctcca acccagtcag ctccaacagg agcgaccccc tcaagctgac tgtaaaatca      600

gatgacaaca ctctaggc                                                    618


<210>  3340
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  3340
aagctcacta ttgaatccat gccgctcagt gtcgcagagg ggaaggaggt gcttctactt       60

gtccacaatc tgccccagca tctttttggc tacagctggt acaaagggga aagagtggat      120

ggcaacagtc taattgtagg atatgtaata ggaactcaac aagctacccc aggggccgca      180

tacagcggtc gagagacaat atacaccaat gcatccctgc tgatccagaa tgtcacccag      240

aatgacatag gattctacac cctacaagtc ataaagtcag atcttgtgaa tgaagaagca      300

actggacagt tccatgtata ccaagaaaat gccccaggcc ttcctgtggg ggccgtcgcc      360

ggc                                                                    363


<210>  3341
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3341
ttcacaatcg aggctctgcc atccagcgcc gctgagggta aagatgtact gttgttggca       60

tgtaacatct ccgaaacaat acaggcgtac tattggcaca aaggtaagac tgcggaaggg      120

tcacctctta ttgctggcta cataacagat atacaagcga atattccagg agccgcctac      180

tcaggcaggg agactgtgta cccgaatggc tccctgcttt ttcaaaacat cacgttagag      240

gacgctggta gttacacttt aagaactatc aatgcctcat acgacagtga ccaggctaca      300

ggccagttgc acgtgcatca gaacaatgtt ccaggcttac cagtgggtgc agtggcaggt      360


<210>  3342
<211>  1953
<212>  DNA
<213>  Homo Sapiens

<400>  3342
aagctcacta ttgaatccac gccgttcaat gtcgcagagg ggaaggaggt gcttctactt       60

gtccacaatc tgccccagca tctttttggc tacagctggt acaaaggtga aagagtggat      120

ggcaaccgtc aaattatagg atatgtaata ggaactcaac aagctacccc agggcccgca      180

tacagtggtc gagagataat ataccccaat gcatccctgc tgatccagaa catcatccag      240

aatgacacag gattctacac cctacacgtc ataaagtcag atcttgtgaa tgaagaagca      300

actggccagt tccgggtata cccggagctg cccaagccct ccatctccag caacaactcc      360

aaacccgtgg aggacaagga tgctgtggcc ttcacctgtg aacctgagac tcaggacgca      420

acctacctgt ggtgggtaaa caatcagagc ctcccggtca gtcccaggct gcagctgtcc      480

aatggcaaca ggaccctcac tctattcaat gtcacaagaa atgactcagc aagctacaaa      540

tgtgaaaccc agaacccagt gagtgccagg cgcagtgatt cagtcatcct gaatgtcctc      600

tatggcccgg atgcccccac catttcccct ctaaacacat cttacagatc aggggaaaat      660

ctgaacctct cctgccacgc agcctctaac ccacctgcac agtactcttg gtttgtcaat      720

gggactttcc agcaatccac ccaagagctc tttatcccca acatcactgt gaataatagt      780

ggatcctata cgtgccaagc ccataactca gacactggcc tcaataggac cacagtcacg      840

acgatcacag tctatgcaga gccacccaaa cccttcatca ccagcaacaa ctccaacccc      900

gtggaggatg aggatgctgt agccttaacc tgtgaacctg agattcagaa cacaacctac      960

ctgtggtggg taaataatca gagcctcccg gtcagtccca ggctgcagct gtccaatgac     1020

aacaggaccc tcactctact cagtgtcaca aggaatgatg taggacccta tgagtgtgga     1080

atccagaacg aattaagtgt tgaccacagc gacccagtca tcctgaatgt cctctatggc     1140

ccagacgacc ccaccatttc cccctcatac acctattacc gtccaggggt gaacctcagc     1200

ctctcctgcc atgcagcctc taacccacct gcacagtatt cttggctgat tgatgggaac     1260

atccagcaac acacacaaga gctctttatc tccaacatca ctgagaagaa cagcggactc     1320

tatacctgcc aggccaataa ctcagccagt ggccacagca ggactacagt caagacaatc     1380

acagtctctg cggagctgcc caagccctcc atctccagca acaactccaa acccgtggag     1440

gacaaggatg ctgtggcctt cacctgtgaa cctgaggctc agaacacaac ctacctgtgg     1500

tgggtaaatg gtcagagcct cccagtcagt cccaggctgc agctgtccaa tggcaacagg     1560

accctcactc tattcaatgt cacaagaaat gacgcaagag cctatgtatg tggaatccag     1620

aactcagtga gtgcaaaccg cagtgaccca gtcaccctgg atgtcctcta tgggccggac     1680

acccccatca tttccccccc agactcgtct tacctttcgg gagcgaacct caacctctcc     1740

tgccactcgg cctctaaccc atccccgcag tattcttggc gtatcaatgg gataccgcag     1800

caacacacac aagttctctt tatcgccaaa atcacgccaa ataataacgg gacctatgcc     1860

tgttttgtct ctaacttggc tactggccgc aataattcca tagtcaagag catcacagtc     1920

tctgcatctg gaacttctcc tggtctctca gct                                  1953


<210>  3343
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  3343
aagctcacta ttgaatccac gccattcaat gtcgcagagg ggaaggaggt tcttctactc       60

gcccacaacc tgccccagaa tcgtattggt tacagctggt acaaaggcga aagagtggat      120

ggcaacagtc taattgtagg atatgtaata ggaactcaac aagctacccc agggcccgca      180

tacagtggtc gagagacaat ataccccaat gcatccctgc tgatccagaa cgtcacccag      240

aatgacacag gattctatac cctacaagtc ataaagtcag atcttgtgaa tgaagaagca      300

accggacagt tccatgtata cccggagctg cccaagccct ccatctccag caacaactcc      360

aaccccgtgg aggacaagga tgctgtggcc ttcacctgtg aacctgaggt tcagaacaca      420

acctacctgt ggtgggtaaa tggtcagagc ctcccggtca gtcccaggct gcagctgtcc      480

aatggcaaca tgaccctcac tctactcagc gtcaaaagga acgatgcagg atcctatgaa      540

tgtgaaatac agaacccagc gagtgccaac cgcagtgacc cagtcaccct gaatgtcctc      600

tatggcccag atgtccccac catttccccc tcaaaggcca attaccgtcc aggggaaaat      660

ctgaacctct cctgccacgc agcctctaac ccacctgcac agtactcttg gtttatcaat      720

gggacgttcc agcaatccac acaagagctc tttatcccca acatcactgt gaataatagc      780

ggatcctata tgtgccaagc ccataactca gccactggcc tcaataggac cacagtcacg      840

atgatcacag tctctgga                                                    858


<210>  3344
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3344
accaatattg atgtcgtgcc gttcaatgtc gcagaaggga aggaggtcct tctagtagtc       60

cataatgagt cccagaatct ttatggctac aactggtaca aaggggaaag ggtgcatgcc      120

aactatcgaa ttataggata tgtaaaaaat ataagtcaag aaaatgcccc agggcccgca      180

cacaacggtc gagagacaat ataccccaat ggaaccctgc tgatccagaa cgtcacccac      240

aatgacgcag gaatctatac cctacacgtt ataaaagaaa atcttgtgaa tgaagaagta      300

accagacaat tctacgtatt ctcggagcca cccaagccct ccatcaccag caacaacttc      360

aatccggtgg agaacaaaga tattgtggtt ttaacctgtc aacctgagac tcagaacaca      420

acctacctgt ggtgggtaaa caatcagagc ctcctggtca gtcccaggct gctgctctcc      480

actgacaaca ggaccctcgt tctactcagc gccacaaaga atgacatagg accctatgaa      540

tgtgaaatac agaacccagt gggtgccagc cgcagtgacc cagtcaccct gaatgtccgc      600

tatgagtcag tacaagcaag t                                                621


<210>  3345
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  3345
cagctcacta ttgaagctgt gccatccaat gctgcagagg ggaaggaggt tcttctactt       60

gtccacaatc tgccccagga ccctcgtggc tacaactggt acaaagggga aacagtggat      120

gccaaccgtc gaattatagg atatgtaata tcaaatcaac agattacccc agggcctgca      180

tacagcaatc gagagacaat ataccccaat gcatccctgc tgatgcggaa cgtcaccaga      240

aatgacacag gatcctacac cctacaagtc ataaagctaa atcttatgag tgaagaagta      300

actggccagt tcagcgtaca tccggagact cccaagccct ccatctccag caacaactcc      360

aaccccgtgg aggacaagga tgctgtggcc ttcacctgtg aacctgagac tcagaacaca      420

acctacctgt ggtgggtaaa tggtcagagt ctcccggtca gtcccaggct gcagctgtcc      480

aatggcaaca ggaccctcac tctactcagt gtcacaagga atgacgtagg accctatgaa      540

tgtgaaatac agaacccagc gagtgcaaac ttcagtgacc cagtcaccct gaatgtcctc      600

tatggcccag atgcccccac catttcccct tcagacacct attaccatgc aggggtaaat      660

ctcaacctct cctgccatgc ggcctctaat ccaccctcac agtattcttg gtctgtcaat      720

ggcacattcc agcaatacac acaaaagctc tttatcccca acatcactac aaagaacagc      780

ggatcctatg cctgccacac cactaactca gccactggcc gcaacaggac cacagtcagg      840

atgatcacag tctctgat                                                    858


<210>  3346
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3346
tatcaaagag agaaacataa cggcggtaga gaggaagtca ccaaggttgc cactcagaag       60

caccgacagt caccgctcaa ctggacctcc agtcatttcg gagaggtgac tgggagcgcc      120

gagggctggg ggccggagga gccgctcccc tactcccggg ctttcggaga gggtgcgtcc      180

gcgcggccgc gctgctgcag gaacggcggt acctgcgtgc tgggcagctt ctgcgtgtgc      240

ccggcccact tcaccggccg ctactgcgag catgaccaga ggcgcagtga atgcggcgcc      300

ctggagcacg gagcctggac cctccgcgcc tgccacctct gcaggtgcat cttcggggcc      360

ctgcactgcc tccccctcca gacgcctgac cgctgtgac                             399


<210>  3347
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  3347
taccaaaggg agaaacacaa cggtggccgt gaggaagtta ccaaggtggc gactcagaaa       60

cacagacagt caccgctgaa ctggactagc agccactttg gcgaggtgac gggttccgct      120

gaaggttggg gacccgagga gcctttacct tacagttggg cgttcggcga aggagcgtcc      180

gctcgtccaa ggtgttgtcg taacggcggg acgtgcgtac tagggagttt ctgcgtatgc      240

ccagcacact tcactggtag atactgcgaa cacgatcaac gtagatccga atgcggtgcc      300

ttagaacacg gagcctggac tttaagagct tgccacctgt gtaggtgcat ctttggagct      360

ttgcattgct taccactaca gacccctgat aggtgcgatc cgaaggactt cctagcttct      420

cacgcgcacg gccctagcgc cggtggcgca cccagtctat tacttttgct accctgtgcg      480

ctactacacc gtcttttaag gccggatgcc ccggcacatc ctagatcact agtcccgtca      540

gtgttacaac gtgagcgtag accatgtggc aggccaggtt tgggccaccg tctg            594


<210>  3348
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  3348
atcctgggcg gcagagaggc cgaggcgcac gcgcggccct acatggcgtc ggtgcagctg       60

aacggcgcgc acctgtgcgg cggcgtcctg gtggcggagc agtgggtgct gagcgcggcg      120

cactgcctgg aggacgcggc cgacgggaag gtgcaggttc tcctgggcgc gcactccctg      180

tcgcagccgg agccctccaa gcgcctgtac gacgtgctcc gcgcagtgcc ccacccggac      240

agccagcccg acaccatcga ccacgacctc ctgctgctac agctgtcgga gaaggccaca      300

ctgggccctg ctgtgcgccc cctgccctgg cagcgcgtgg accgcgacgt ggcaccggga      360

actctctgcg acgtggccgg ctggggcata gtcaaccacg cgggccgccg cccggacagc      420

ctgcagcacg tgctcttgcc agtgctggac cgcgccacct gcaaccggcg cacgcaccac      480

gacggcgcca tcaccgagcg cttgatgtgc gcggagagca atcgccggga cagctgcaag      540

ggtgactccg ggggcccgct ggtgtgcggg ggcgtgctcg agggcgtggt cacctcgggc      600

tcgcgcgttt gcggcaaccg caagaagccc gggatctaca cccgcgtggc gagctatgcg      660

gcctggatcg acagcgtcct ggcc                                             684


<210>  3349
<211>  3639
<212>  DNA
<213>  Homo Sapiens

<400>  3349
gaagattgca atgaacttcc tccaagaaga aatacagaaa ttctgacagg ttcctggtct       60

gaccaaacat atccagaagg cacccaggct atctataaat gccgccctgg atatagatct      120

cttggaaata taataatggt atgcaggaag ggagaatggg ttgctcttaa tccattaagg      180

aaatgtcaga aaaggccctg tggacatcct ggagatactc cttttggtac ttttaccctt      240

acaggaggaa atgtgtttga atatggtgta aaagctgtgt atacatgtaa tgaggggtat      300

caattgctag gtgagattaa ttaccgtgaa tgtgacacag atggatggac caatgatatt      360

cctatatgtg aagttgtgaa gtgtttacca gtgacagcac cagagaatgg aaaaattgtc      420

agtagtgcaa tggaaccaga tcgggaatac cattttggac aagcagtacg gtttgtatgt      480

aactcaggct acaagattga aggagatgaa gaaatgcatt gttcagacga tggtttttgg      540

agtaaagaga aaccaaagtg tgtggaaatt tcatgcaaat ccccagatgt tataaatgga      600

tctcctatat ctcagaagat tatttataag gagaatgaac gatttcaata taaatgtaac      660

atgggttatg aatacagtga aagaggagat gctgtatgca ctgaatctgg atggcgtccg      720

ttgccttcat gtgaagaaaa atcatgtgat aatccttata ttccaaatgg tgactactca      780

cctttaagga ttaaacacag aactggagat gaaatcacgt accagtgtag aaatggtttt      840

tatcctgcaa cccggggaaa tacagccaaa tgcacaagta ctggctggat acctgctccg      900

agatgtacct tgaaaccttg tgattatcca gacattaaac atggaggtct atatcatgag      960

aatatgcgta gaccatactt tccagtagct gtaggaaaat attactccta ttactgtgat     1020

gaacattttg agactccgtc aggaagttac tgggatcaca ttcattgcac acaagatgga     1080

tggtcgccag cagtaccatg cctcagaaaa tgttattttc cttatttgga aaatggatat     1140

aatcaaaatt atggaagaaa gtttgtacag ggtaaatcta tagacgttgc ctgccatcct     1200

ggctacgctc ttccaaaagc gcagaccaca gttacatgta tggagaatgg ctggtctcct     1260

actcccagat gcatccgtgt caaaacatgt tccaaatcaa gtatagatat tgagaatggg     1320

tttatttctg aatctcagta tacatatgcc ttaaaagaaa aagcaaaata tcaatgcaaa     1380

ctaggatatg taacagcaga tggtgaaaca tcaggatcaa ttacatgtgg gaaagatgga     1440

tggtcagctc aacccacgtg cattaaatct tgtgatatcc cagtatttat gaatgccaga     1500

actaaaaatg acttcacatg gtttaagctg aatgacacat tggactatga atgccatgat     1560

ggttatgaaa gcaatactgg aagcaccact ggttccatag tgtgtggtta caatggttgg     1620

tctgatttac ccatatgtta tgaaagagaa tgcgaacttc ctaaaataga tgtacactta     1680

gttcctgatc gcaagaaaga ccagtataaa gttggagagg tgttgaaatt ctcctgcaaa     1740

ccaggattta caatagttgg acctaattcc gttcagtgct accactttgg attgtctcct     1800

gacctcccaa tatgtaaaga gcaagtacaa tcatgtggtc cacctcctga actcctcaat     1860

gggaatgtta aggaaaaaac gaaagaagaa tatggacaca gtgaagtggt ggaatattat     1920

tgcaatccta gatttctaat gaagggacct aataaaattc aatgtgttga tggagagtgg     1980

acaactttac cagtgtgtat tgtggaggag agtacctgtg gagatatacc tgaacttgaa     2040

catggctggg cccagctttc ttcccctcct tattactatg gagattcagt ggaattcaat     2100

tgctcagaat catttacaat gattggacac agatcaatta cgtgtattca tggagtatgg     2160

acccaacttc cccagtgtgt ggcaatagat aaacttaaga agtgcaaatc atcaaattta     2220

attatacttg aggaacattt aaaaaacaag aaggaattcg atcataattc taacataagg     2280

tacagatgta gaggaaaaga aggatggata cacacagtct gcataaatgg aagatgggat     2340

ccagaagtga actgctcaat ggcacaaata caattatgcc cacctccacc tcagattccc     2400

aattctcaca atatgacaac cacactgaat tatcgggatg gagaaaaagt atctgttctt     2460

tgccaagaaa attatctaat tcaggaagga gaagaaatta catgcaaaga tggaagatgg     2520

cagtcaatac cactctgtgt tgaaaaaatt ccatgttcac aaccacctca gatagaacac     2580

ggaaccatta attcatccag gtcttcacaa gaaagttatg cacatgggac taaattgagt     2640

tatacttgtg agggtggttt caggatatct gaagaaaatg aaacaacatg ctacatggga     2700

aaatggagtt ctccacctca gtgtgaaggc cttccttgta aatctccacc tgagatttct     2760

catggtgttg tagctcacat gtcagacagt tatcagtatg gagaagaagt tacgtacaaa     2820

tgttttgaag gttttggaat tgatgggcct gcaattgcaa aatgcttagg agaaaaatgg     2880

tctcaccctc catcatgcat aaaaacagat tgtctcagtt tacctagctt tgaaaatgcc     2940

atacccatgg gagagaagaa ggatgtgtat aaggcgggtg agcaagtgac ttacacttgt     3000

gcaacatatt acaaaatgga tggagccagt aatgtaacat gcattaatag cagatggaca     3060

ggaaggccaa catgcagaga cacctcctgt gtgaatccgc ccacagtaca aaatgcttat     3120

atagtgtcga gacagatgag taaatatcca tctggtgaga gagtacgtta tcaatgtagg     3180

agcccttatg aaatgtttgg ggatgaagaa gtgatgtgtt taaatggaaa ctggacggaa     3240

ccacctcaat gcaaagattc tacaggaaaa tgtgggcccc ctccacctat tgacaatggg     3300

gacattactt cattcccgtt gtcagtatat gctccagctt catcagttga gtaccaatgc     3360

cagaacttgt atcaacttga gggtaacaag cgaataacat gtagaaatgg acaatggtca     3420

gaaccaccaa aatgcttaca tccgtgtgta atatcccgag aaattatgga aaattataac     3480

atagcattaa ggtggacagc caaacagaag ctttattcga gaacaggtga atcagttgaa     3540

tttgtgtgta aacggggata tcgtctttca tcacgttctc acacattgcg aacaacatgt     3600

tgggatggga aactggagta tccaacttgt gcaaaaaga                            3639


<210>  3350
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  3350
gaagtgaaac cttgtgattt tccagaaatt caacatggag gtctatatta taagagtttg       60

cgtagactat actttccagc agctgcagga caatcttact cctattactg tgaccaaaat      120

tttgtgactc cttcaggaag ttactgggat tacattcact gcacacaaga tgggtggttg      180

ccaacagtcc catgcctcag aacatgctca aaatcagata tagaaattga aaatggattc      240

atttctgaat cttcctctat ttatatttta aataaagaaa tacaatataa atgtaaacca      300

ggatatgcaa cagcagatgg aaattcttca ggttcaatta catgtttgca aaatggatgg      360

tcagcacaac caatttgcat taaattttgt gatatgcctg tttttgagaa ttccagagcc      420

aagagtaatg gcatgcggtt taagctccat gacacattgg actacgaatg ctacgatgga      480

tatgaaatca gttatggaaa caccacaggt tccatagtgt gtggtgaaga tgggtggtcc      540

catttcccaa catgttataa ttcttcagaa aagtgtgggc ctcctccacc tattagcaat      600

ggtgatacca cctcctttct actaaaagtg tatgtgccac agtcaagagt cgagtaccaa      660

tgccagtcct actatgaact tcagggttct aattatgtaa catgtagtaa tggagagtgg      720

tcggaaccac caagatgcat acatccatgt ataataactg aagaaaacat gaataaaaat      780

aacatacagt taaaaggaaa aagtgacata aaatattatg caaaaacagg ggataccatt      840

gaatttatgt gtaaattggg atataatgcg aatacatcag ttctatcatt tcaagcagtg      900

tgtagggaag gcatagtgga ataccccaga tgcgaa                                936


<210>  3351
<211>  1077
<212>  DNA
<213>  Homo Sapiens

<400>  3351
aaggtcactt atacatctca agaggatctg gtggagaaaa agtgcttagc aaaaaaatat       60

actcacctct cctgcgataa agtcttctgc cagccatggc agagatgcat tgagggcacc      120

tgtgtttgta aactaccgta tcagtgccca aagaatggca ctgcagtgtg tgcaactaac      180

aggagaagct tcccaacata ctgtcaacaa aagagtttgg aatgtcttca tccagggaca      240

aagtttttaa ataacggaac atgcacagcc gaaggaaagt ttagtgtttc cttgaagcat      300

ggaaatacag attcagaggg aatagttgaa gtaaaacttg tggaccaaga taagacaatg      360

ttcatatgca aaagcagctg gagcatgagg gaagccaacg tggcctgcct tgaccttggg      420

tttcaacaag gtgctgatac tcaaagaagg tttaagttgt ctgatctctc tataaattcc      480

actgaatgtc tacatgtgca ttgccgagga ttagagacca gtttggctga atgtactttt      540

actaagagaa gaactatggg ttaccaggat ttcgctgatg tggtttgtta tacacagaaa      600

gcagattctc caatggatga cttctttcag tgtgtgaatg ggaaatacat ttctcagatg      660

aaagcctgtg atggtatcaa tgattgtgga gaccaaagtg atgaactgtg ttgtaaagca      720

tgccaaggca aaggcttcca ttgcaaatcg ggtgtttgca ttccaagcca gtatcaatgc      780

aatggtgagg tggactgcat tacaggggaa gatgaagttg gctgtgcagg ctttgcatct      840

gtggctcaag aagaaacaga aattttgact gctgacatgg atgcagaaag aagacggata      900

aaatcattat tacctaaact atcttgtgga gttaaaaaca gaatgcacat tcgaaggaaa      960

cgaattgtgg gaggaaagcg agcacaactg ggaaaaatga agcaaatctc attggatatt     1020

tttaaaggtc tccacagagt ttatgccata ttggaatttt gttgtataat tctcaaa        1077


<210>  3352
<211>  1011
<212>  DNA
<213>  Homo Sapiens

<400>  3352
tgcccccaga actgccactg ccacagcgac ctgcagcacg tcatctgcga caaggtgggg       60

ctgcagaaga tccccaaggt gtcagagaag accaagctgc tcaacctaca gcgcaacaac      120

ttcccggtgc tggctgccaa ttcgttccgg gccatgccga acctcgtgtc attgcacctg      180

cagcactgcc agatccgcga ggtggccgcc ggtgccttcc gcggcctcaa gcaacttatc      240

tacttgtacc tgtcccataa cgacatccgc gtgctgcgcg caggtgcctt cgacgacctg      300

accgagctga cctacctcta cctggaccac aacaaggtca ctgagctgcc ccgggggttg      360

ctctccccgc tggtcaacct cttcatcttg cagctcaaca acaacaagat ccgtgagctg      420

cgcgcaggcg ccttccaggg agccaaggac ctgcgctggc tctacctgtc ggaaaacgcg      480

ttgagctccc tgcagcccgg ggccctggac gacgtggaga acctcgccaa attccacgtg      540

gacaggaacc agctgtccag ctacccctca gctgccctga gcaagctacg ggtggtggag      600

gagctgaagc tgtcccacaa ccccctgaaa agcatcccgg acaatgcctt ccagtccttt      660

ggcagatacc tggagaccct ctggctggac aacaccaacc tggagaagtt ctcagatggt      720

gccttcctgg gtgtaaccac gctgaaacac gtccatttgg agaacaaccg cttgaaccag      780

ctaccctcca acttcccctt cgacagcctg gagaccctcg cccttaccaa taacccctgg      840

aagtgtacct gccagctccg gggccttcgg cggtggctgg aagccaaggc ctcccgccca      900

gatgccacct gtgcctcacc tgccaagttc aagggccagc acatccgtga cacggacgcc      960

ttccgcagct gcaagttccc caccaagagg tccaagaaag ctggccgcca t              1011


<210>  3353
<211>  2196
<212>  DNA
<213>  Homo Sapiens

<400>  3353
cagcgctgcc cacaggcctg catctgtgac aactccaggc gacacgttgc ctgccggtac       60

cagaacctca ctgaggtgcc agacgccatc cctgagctga cccagcggct ggacctgcag      120

ggcaatttgc tgaaggtgat ccccgcagcc gccttccagg gcgtgcctca cctcacacac      180

ctggacctgc gccactgcga ggtggagctg gtggccgagg gcgccttccg tggcctgggc      240

cgcctgctcc tgctcaacct ggcctccaac cacctgcgtg agctgcccca ggaggcgctg      300

gacgggctgg gctcgttgcg gcggctggag ctggagggga acgcactgga ggagctgcgg      360

ccggggacgt tcggggcact gggtgcgctg gccacgctaa acctggccca caacgccctg      420

gtttacctgc ccgccatggc cttccagggg ctactgcgcg tccgctggct gcggctgtcg      480

cacaacgcgc tcagcgtgct ggcccccgag gccctggctg gcctgcccgc cctgagacgg      540

ctcagcctac accacaacga gctccaggct ctgcccgggc ctgtcttgtc ccaggcccgc      600

ggcctggccc gtctggagct gggccacaac ccgctcacct acgcgggcga ggaggacggg      660

ctggcgctgc ccggcctgcg ggagctgctg ctggacggcg gggccctgca ggccctgggt      720

cccagggcct tcgcacactg tccgcgcctg cacaccctcg acctccgcgg gaaccagcta      780

gacaccctgc ccccgctgca gggcccgggc cagctgcgcc ggctgcggct gcaggggaat      840

ccgctgtggt gcggctgcca ggcgcggccc ctactcgagt ggctggcgcg ggcgcgcgtg      900

cgctcggacg gcgcgtgcca ggggccgcgg cgcctgcggg gcgaggctct ggacgccctg      960

cggccctggg acctgcgctg ccctggggac gcggcgcagg aagaggaaga gctggaagag     1020

cgggctgtgg ccgggccccg cgcccctccg cgcggccctc cgcgcggccc cggggaggag     1080

cgggcagtcg cgccttgccc tcgcgcctgc gtgtgcgtcc ccgagtcccg gcacagcagc     1140

tgcgagggct gcggcctgca ggcggtgccc cgcggcttcc gcagcgacac ccagctcctg     1200

gacctgaggc ggaaccactt cccctcggtg ccccgagcgg ccttccccgg cctgggccac     1260

ctggtgtcgc tgcacctgca gcactgcggc atcgcggagc tggaagcggg cgccctggcc     1320

gggctgggcc gcctgatcta cctgtacctc tccgacaacc agctcgcagg cctcagcgct     1380

gctgcccttg aaggggctcc ccgcctcggc tacctgtacc tagaacgcaa ccgtttcctg     1440

caggtgccag gggctgccct gcgcgccctg cccagcctct tctccctgca cctgcatgac     1500

aacgctgtgg accgcctggc acctggggac ctggggagaa cacgggcctt gcgctgggtc     1560

tacctgagtg gaaaccgcat caccgaagtg tcccttgggg cgctgggccc agctcgggag     1620

ctggagaagc tgcacctgga caggaatcag ctgcgagagg tgcccactgg ggccttggag     1680

gggctgcctg ccctcctgga gctgcagctc tcgggcaacc cactcagggc cttgcgtgac     1740

ggagccttcc agcctgtggg caggtcgctg cagcacctct tcctgaacag cagtggcctg     1800

gagcagattt gtcctggggc cttttcaggc ctggggcccg ggctccagag cctgcacctg     1860

cagaagaacc agcttcgggc cctgcctgcc ctgcccagtc tcagccagct ggagctcatc     1920

gacctcagca gcaatccctt ccactgtgac tgccagctgc ttccgctgca caggtggctt     1980

actgggctga acctgcgggt gggggccacc tgcgccaccc ctcccaatgc ccgtggccag     2040

agggtgaagg ctgcagctgc tgtctttgaa gactgcccgg gctgggctgc cagaaaggcc     2100

aagcggacac cagcctccag gcccagtgcc aggagaaccc ccatcaaagg aagacagtgt     2160

ggagcagata aggtggggaa ggagaagggt cgtctc                               2196


<210>  3354
<211>  3174
<212>  DNA
<213>  Homo Sapiens

<400>  3354
attgaaatac catcttcagt tcaacaggtt ccaacaatca taaaacagtc aaaagtccaa       60

gttgcctttc ccttcgatga gtattttcaa attgaatgtg aagctaaagg aaatccagaa      120

ccaacatttt cgtggactaa ggatggcaac cctttttatt tcactgacca tcggataatt      180

ccatcgaaca attcaggaac attcaggatc ccaaacgagg ggcacatatc tcactttcaa      240

gggaaatacc gctgctttgc ttcaaataaa ctgggaatcg ctatgtcaga agaaatagaa      300

tttatagttc caagtgttcc aaaattccca aaagaaaaaa ttgaccctct tgaagtggag      360

gagggagatc caattgtcct cccatgcaat cctcccaaag gcctcccacc tttacacatt      420

tattggatga atattgaatt agaacacatc gaacaagatg aaagagtata catgagccaa      480

aagggagatc tatacttcgc aaacgtggaa gaaaaggaca gtcgcaatga ctactgttgc      540

tttgctgcat ttccaagatt aaggactatt gtacagaaaa tgccaatgaa actaacagtt      600

aacagttcaa attccatcaa gcaaagaaaa cccaaactgc tgttgcctcc cactgagagt      660

ggcagtgagt cttcaattac catcctcaaa ggggaaatct tgctgcttga gtgttttgct      720

gaaggcttgc caactccaca ggttgattgg aacaaaattg gtggtgactt accaaagggg      780

agagaagcaa aagaaaatta tggcaagact ttgaagatag agaatgtctc ctaccaggac      840

aaaggaaatt atcgctgcac agccagcaat ttcttgggaa cagccactca cgattttcac      900

gttatagtag aagagcctcc tcgctggaca aagaagcctc agagtgctgt gtatagcacc      960

ggaagcaatg gcatcttgtt atgtgaggct gaaggagaac ctcaacccac aatcaagtgg     1020

agagtcaatg gctccccagt tgacaatcat ccatttgctg gtgatgttgt cttccccagg     1080

gaaatcagtt ttaccaacct tcaaccaaat catactgctg tgtaccagtg tgaagcctca     1140

aatgtccatg gaactatcct tgccaatgcc aatattgatg ttgtggatgt ccgtccattg     1200

atacaaacca aagatggaga aaattacgct acagtggttg ggtacagtgc tttcttacat     1260

tgcgagttct ttgcttcacc tgaggcagtc gtgtcctggc agaaggtgga agaagtgaaa     1320

cccctggagg gcaggcggta tcatatctat gaaaatggca cattgcagat caacagaacc     1380

accgaagaag atgctgggtc ttactcatgt tgggtagaaa atgctatagg aaaaactgca     1440

gtcacagcca atttggatat tagaaatgct acaaaactta gagtttctcc taagaatcct     1500

cgtatcccca aattgcatat gcttgaatta cattgtgaaa gcaaatgtga ctcacatttg     1560

aaacacagtt tgaagttgtc ctggagtaaa gatggagaag cctttgaaat taatggcaca     1620

gaagatggca ggataattat tgatggagct aatttgacca tatctaatgt aactttagag     1680

gaccaaggta tttactgctg ttcagctcat actgctctag acagtgctgc cgatataact     1740

caagtaactg ttcttgatgt tccggatcca ccagaaaacc ttcacttgtc tgaaagacag     1800

aacaggagtg ttcggctgac ctgggaagct ggagctgacc acaacagcaa tattagcgag     1860

tatattgttg aatttgaagg aaacaaagaa gagcctggaa ggtgggagga actgaccaga     1920

gtccaaggaa agaaaaccac agttatctta cctttggctc catttgtgag ataccagttc     1980

agggtcatag ccgtgaacga agtagggaga agtcagccta gccagccgtc agaccatcat     2040

gaaacaccac cagcagctcc agataggaat ccacaaaaca taagggttca agcctctcaa     2100

cccaaggaaa tgattataaa gtgggagcct ttgaaatcca tggagcagaa tggaccaggc     2160

ctagagtaca gagtgacctg gaagccacag ggagccccag tggagtggga agaagaaaca     2220

gtcacaaacc acacattgcg ggtgatgacg cctgctgtct atgcccctta tgatgtcaag     2280

gtccaggcta tcaatcaact aggatctggg cctgaccctc agtcagtgac tctctattct     2340

ggagaagact atcctgatac agctccagtg atccatgggg tggacgttat aaacagtaca     2400

ttagttaaag ttacctggtc aacagttcca aaggacagag tacatggacg tctgaaaggc     2460

tatcagataa attggtggaa aacaaaaagt ctgttggatg gaagaacaca tcccaaagaa     2520

gtgaacattc taagattttc aggacaaaga aactctggaa tggttccttc cttagatgcc     2580

tttagtgaat ttcatttaac agtcttagcc tataactcta aaggagctgg tcctgaaagt     2640

gagccttata tatttcaaac accagaagga gtacctgaac agccaacttt tctaaaggtc     2700

atcaaagttg ataaagacac tgccacttta tcttggggac tacctaagaa attaaatgga     2760

aacttaactg gctatctttt gcaatatcag ataataaatg acacctacga gattggagaa     2820

ttaaatgata ttaacattac aactccatca aagcccagct ggcacctctc aaacctgaat     2880

gcaactacca agtacaaatt ctacttgagg gcttgcactt cacagggctg tggaaaaccg     2940

atcacggagg aaagctccac cttaggagaa gggagtaaag gtatcgggaa gatatcagga     3000

gtaaatctta ctcaaaagac tcacccagta gaggtatttg agccgggagc tgaacatata     3060

gttcgcctaa tgactaagaa ttggggcgat aacgatagca tttttcaaga tgtaattgag     3120

acaagaggga gagaatatgc tggtttatat gatgacatct ccactcaagg ctgg           3174


<210>  3355
<211>  585
<212>  DNA
<213>  Homo Sapiens

<400>  3355
cgccgcgtgg tcagcggcca aaaggtgtgt tttgctgact tcaagcatcc ctgctacaaa       60

atggcctact tccatgaact gtccagccga gtgagctttc aggaggcacg cctggcttgt      120

gagagtgagg gaggagtcct cctcagcctt gagaatgaag cagaacagaa gttaatagag      180

agcatgttgc aaaacctgac aaaacccggg acagggattt ctgatggtga tttctggata      240

gggctttgga ggaatggaga tgggcaaaca tctggtgcct gcccagatct ctaccagtgg      300

tctgatggaa gcaattccca gtaccgaaac tggtacacag atgaaccttc ctgcggaagt      360

gaaaagtgtg ttgtgatgta tcaccaacca actgccaatc ctggccttgg gggtccctac      420

ctttaccagt ggaatgatga caggtgtaac atgaagcaca attatatttg caagtatgaa      480

ccagagatta atccaacagc ccctgtagaa aagccttatc ttacaaatca accaggagac      540

acccatcaga atgtggttgt tactgaagca ggtataattc ccaat                      585


<210>  3356
<211>  3489
<212>  DNA
<213>  Homo Sapiens

<400>  3356
agacagacga tgctcaccca gtcagtaaga agagtccagc ctgggaagaa gaaccccagc       60

atctttgcca agcctgccga caccctggag agccctggtg agtggacaac atggttcaac      120

atcgactacc caggcgggaa gggcgactat gagcggctgg acgccattcg cttctactat      180

ggggaccgtg tatgtgcccg tcccctgcgg ctagaggctc ggaccactga ctggacacct      240

gcgggcagca ctggccaggt ggtccatggt agtccccgtg agggtttctg gtgcctcaac      300

agggagcagc ggcctggcca gaactgctct aattacaccg tacgcttcct ctgcccacca      360

ggatccctgc gccgagacac agagcgcatc tggagcccat ggtctccctg gagcaagtgc      420

tcagctgcct gtggtcagac tggggtccag actcgcacac gcatttgctt ggcagagatg      480

gtgtcgctgt gcagtgaggc cagcgaagag ggtcagcact gcatgggcca ggactgtaca      540

gcctgtgacc tgacctgccc aatgggccag gtgaatgctg actgtgatgc ctgcatgtgc      600

caggacttca tgcttcatgg ggctgtctcc cttcccggag gtgccccagc ctcaggggct      660

gctatctacc tcctgaccaa gacgccgaag ctgctgaccc agacagacag tgatgggaga      720

ttccgaatcc ctggcttgtg ccctgatggc aaaagcatcc tgaagatcac aaaggtcaag      780

tttgccccca ttgtactcac aatgcccaag actagcctga aggcagccac catcaaggca      840

gagtttgtga gggcagagac tccatacatg gtgatgaacc ctgagacaaa agcacggaga      900

gctgggcaga gcgtgtctct gtgctgtaag gccacaggga agcccaggcc agacaagtat      960

ttttggtatc ataatgacac attgctggat ccttccctct acaagcatga gagcaagctg     1020

gtgctgagga aactgcagca gcaccaggct ggggagtact tttgcaaggc ccagagtgat     1080

gctggggctg tgaagtccaa ggttgcccag ctgattgtca tagcatctga tgagactcct     1140

tgcaacccag ttcctgagag ctatcttatc cggctgcccc atgattgctt tcagaatgcc     1200

accaactcct tctactatga cgtgggacgc tgccctgtta agacttgtgc agggcagcag     1260

gataatggga tcaggtgccg tgatgctgtg cagaactgct gtggcatctc caagacagag     1320

gaaagggaga tccagtgcag tggctacacg ctacccacca aggtggccaa ggagtgcagc     1380

tgccagcggt gtacggaaac tcggagcatc gtgcggggcc gtgtcagtgc tgctgacaat     1440

ggggagccca tgcgctttgg ccatgtgtac atggggaaca gccgtgtaag catgactggc     1500

tacaagggca ctttcaccct ccatgtcccc caggacactg agaggctggt gctcacattt     1560

gtggacaggc tgcagaagtt tgtcaacacc accaaagtgc tacctttcaa caagaagggg     1620

agtgccgtgt tccatgaaat caagatgctt cgtcggaaag agcccatcac tttggaagcc     1680

atggagacca acatcatccc cctgggggaa gtggttggtg aagaccccat ggctgaactg     1740

gagattccat ccaggagttt ctacaggcag aatggggagc cctacatagg aaaagtgaag     1800

gccagtgtga ccttcctgga tccccggaat atttccacag ccacagctgc ccagactgac     1860

ctgaacttca tcaatgacga aggagacact ttcccccttc ggacgtatgg catgttctct     1920

gtggacttca gagatgaggt cacctcagag ccacttaatg ctggcaaagt gaaggtccac     1980

cttgactcga cccaggtcaa gatgccagag cacatatcca cagtgaaact ctggtcactc     2040

aatccagaca cagggctgtg ggaggaggaa ggtgatttca aatttgaaaa tcaaaggagg     2100

aacaaaagag aagacagaac cttcctggtg ggcaacctgg agattcgtga gaggaggctc     2160

tttaacctgg atgttcctga aagcaggcgg tgctttgtta aggtgagggc ctaccggagt     2220

gagaggttct tgcctagtga gcagatccag ggggttgtga tctccgtgat taacctggag     2280

cctagaactg gcttcttgtc caaccctagg gcctggggcc gctttgacag tgtcatcaca     2340

ggccccaacg gggcctgtgt gcctgccttc tgtgatgacc agtcccctga tgcctactct     2400

gcctatgtct tggcaagcct ggctggggag gaactgcaag cagtggagtc ttctcctaaa     2460

ttcaacccaa atgcaattgg cgtccctcag ccctatctca acaagctcaa ctaccgtcgg     2520

acggaccatg aggatccacg ggttaaaaag acagctttcc agattagcat ggccaagcca     2580

aggcccaact cagctgagga gagcaatggg cccatctatg cctttgagaa cctccgggca     2640

tgtgaagagg caccacccag tgcagcccac ttccggttct accagattga gggggatcga     2700

tatgactaca acacagtccc cttcaacgaa gatgacccta tgagctggac tgaagactat     2760

ctggcatggt ggccaaagcc gatggaattc agggcctgct atatcaaggt gaagattgtg     2820

gggccactgg aagtgaatgt gcgatcccgc aacatggggg gcactcatcg gcggacagtg     2880

gggaagctgt atggaatccg agatgtgagg agcactcggg acagggacca gcccaatgtc     2940

tcagctgcct gtctggagtt caagtgcagt gggatgctct atgatcagga ccgtgtggac     3000

cgcaccctgg tgaaggtcat cccccagggc agctgccgtc gagccagtgt gaaccccatg     3060

ctgcatgagt acctggtcaa ccacttgcca cttgcagtca acaacgacac cagtgagtac     3120

accatgctgg cacccttgga cccactgggc cacaactatg gcatctacac tgtcactgac     3180

caggaccctc gcacggccaa ggagatcgcg ctcggccggt gctttgatgg cacatccgat     3240

ggctcctcca gaatcatgaa gagcaatgtg ggagtagccc tcaccttcaa ctgtgtagag     3300

aggcaagtag gccgccagag tgccttccag tacctccaaa gcaccccagc ccagtcccct     3360

gctgcaggca ctgtccaagg aagagtgccc tcgaggaggc agcagcgagc gagcaggggt     3420

ggccagcgcc agagtggagt ggtggcctct ctgagatttc ctagagttgc tcaacagccc     3480

ctgatcaac                                                             3489


<210>  3357
<211>  1341
<212>  DNA
<213>  Homo Sapiens

<400>  3357
gaggagcgcg tcttcctggt gggcaacgtg gagatccggg agcggcgcct gttcaatctg       60

gacgtgcctg agcgccgccg ctgcttcgtg aaggtgcgcg cctacgccaa cgacaagttc      120

acccccagcg agcaggtgga gggcgtggtg gtcacgctgg tcaatctgga gcccgccccc      180

ggcttctccg ccaacccccg tgcctggggc cgctttgaca gcgcggtcac cggccccaat      240

ggcgcctgcc tccccgcctt ctgcgacgcc gacaggccag acgcctacac cgccctggtc      300

accgccaccc tgggcggcga ggagctggag ccggcccctt ccttgccccg cccactcccg      360

gccaccgtgg gcgtcaccca gccctacctg gacaggctgg ggtaccgtcg gacggaccac      420

gacgatcccg ccttcaagcg taacggcttc cgcatcaacc tcgccaagcc caggccaggt      480

gaccccgccg aggccaatgg gcctgtgtac ccgtggcgca gcctgcggga atgccagggg      540

gccccggtga ctgccagcca cttccgcttc gccagggtgg aggcggacaa gtacgagtac      600

aacgtggtcc ccttccgaga gggcacacct gcctcctgga ctggcgatct cctggcctgg      660

tggcccaacc cgcaggagtt ccgggcctgc ttcctcaagg tgaagatcca gggtccccag      720

gagtatatgg tccgctccca caacgcaggg ggcagccacc cacgcacccg cggccagctc      780

tacggacttc gggatgcccg gagtgtgcga gaccccgagc gtccgggcac ctcggcagcc      840

tgcgtggagt tcaagtgcag cgggatgctg ttcgaccagc ggcaggtgga caggacgctg      900

gtgaccatta tgccccaggg cagctgccgg cgcgtggccg tcaacggact ccttcgggat      960

tacctgaccc ggcacccccc accggtgccc gcggaggacc cagctgcctt ctccatgctg     1020

gcccccctag accctctggg ccacaactat ggcgtctaca ctgtcactga ccagagccca     1080

cgcttggcca aggagatcgc cattggccgc tgctttgatg gttcctctga cggcttctcc     1140

agagagatga aggctgatgc cggcacagcc gtcaccttcc agtgccggga gccaccggcc     1200

ggacgaccca gcctcttcca gaggctgctg gagtccccgg cgacagcact tggtgacatc     1260

cgcagggaga tgagcgaggc ggcgcaggca caggcccggg cctcaggtcc cctccgcacc     1320

cgccggggta gggtccggca g                                               1341


<210>  3358
<211>  2610
<212>  DNA
<213>  Homo Sapiens

<400>  3358
ggagtacagc ttcaagacaa tgggtataat ggattgctca ttgcaattaa tcctcaggta       60

cctgagaatc agaacctcat ctcaaacatt aaggaaatga taactgaagc ttcattttac      120

ctatttaatg ctaccaagag aagagtattt ttcagaaata taaagatttt aatacctgcc      180

acatggaaag ctaataataa cagcaaaata aaacaagaat catatgaaaa ggcaaatgtc      240

atagtgactg actggtatgg ggcacatgga gatgatccat acaccctaca atacagaggg      300

tgtggaaaag agggaaaata cattcatttc acacctaatt tcctactgaa tgataactta      360

acagctggct acggatcacg aggccgagtg tttgtccatg aatgggccca cctccgttgg      420

ggtgtgttcg atgagtataa caatgacaaa cctttctaca taaatgggca aaatcaaatt      480

aaagtgacaa ggtgttcatc tgacatcaca ggcatttttg tgtgtgaaaa aggtccttgc      540

ccccaagaaa actgtattat tagtaagctt tttaaagaag gatgcacctt tatctacaat      600

agcacccaaa atgcaactgc atcaataatg ttcatgcaaa gtttatcttc tgtggttgaa      660

ttttgtaatg caagtaccca caaccaagaa gcaccaaacc tacagaacca gatgtgcagc      720

ctcagaagtg catgggatgt aatcacagac tctgctgact ttcaccacag ctttcccatg      780

aatgggactg agcttccacc tcctcccaca ttctcgcttg tacaggctgg tgacaaagtg      840

gtctgtttag tgctggatgt gtccagcaag atggcagagg ctgacagact ccttcaacta      900

caacaagccg cagaatttta tttgatgcag attgttgaaa ttcatacctt cgtgggcatt      960

gccagtttcg acagcaaagg agagatcaga gcccagctac accaaattaa cagcaatgat     1020

gatcgaaagt tgctggtttc atatctgccc accactgtat cagctaaaac agacatcagc     1080

atttgttcag ggcttaagaa aggatttgag gtggttgaaa aactgaatgg aaaagcttat     1140

ggctctgtga tgatattagt gaccagcgga gatgataagc ttcttggcaa ttgcttaccc     1200

actgtgctca gcagtggttc aacaattcac tccattgccc tgggttcatc tgcagcccca     1260

aatctggagg aattatcacg tcttacagga ggtttaaagt tctttgttcc agatatatca     1320

aactccaata gcatgattga tgctttcagt agaatttcct ctggaactgg agacattttc     1380

cagcaacata ttcagcttga aagtacaggt gaaaatgtca aacctcacca tcaattgaaa     1440

aacacagtga ctgtggataa tactgtgggc aacgacacta tgtttctagt tacgtggcag     1500

gccagtggtc ctcctgagat tatattattt gatcctgatg gacgaaaata ctacacaaat     1560

aattttatca ccaatctaac ttttcggaca gctagtcttt ggattccagg aacagctaag     1620

cctgggcact ggacttacac cctgaacaat acccatcatt ctctgcaagc cctgaaagtg     1680

acagtgacct ctcgcgcctc caactcagct gtgcccccag ccactgtgga agcctttgtg     1740

gaaagagaca gcctccattt tcctcatcct gtgatgattt atgccaatgt gaaacaggga     1800

ttttatccca ttcttaatgc cactgtcact gccacagttg agccagagac tggagatcct     1860

gttacgctga gactccttga tgatggagca ggtgctgatg ttataaaaaa tgatggaatt     1920

tactcgaggt attttttctc ctttgctgca aatggtagat atagcttgaa agtgcatgtc     1980

aatcactctc ccagcataag caccccagcc cactctattc cagggagtca tgctatgtat     2040

gtaccaggtt acacagcaaa cggtaatatt cagatgaatg ctccaaggaa atcagtaggc     2100

agaaatgagg aggagcgaaa gtggggcttt agccgagtca gctcaggagg ctccttttca     2160

gtgctgggag ttccagctgg cccccaccct gatgtgtttc caccatgcaa aattattgac     2220

ctggaagctg taaaagtaga agaggaattg accctatctt ggacagcacc tggagaagac     2280

tttgatcagg gccaggctac aagctatgaa ataagaatga gtaaaagtct acagaatatc     2340

caagatgact ttaacaatgc tattttagta aatacatcaa agcgaaatcc tcagcaagct     2400

ggcatcaggg agatatttac gttctcaccc caaatttcca cgaatggacc tgaacatcag     2460

ccaaatggag aaacacatga aagccacaga atttatgttg caatacgagc aatggatagg     2520

aactccttac agtctgctgt atctaacatt gcccaggcgc ctctgtttat tccccccaat     2580

tctgatcctg tacctgccag agattatctt                                      2610


<210>  3359
<211>  2613
<212>  DNA
<213>  Homo Sapiens

<400>  3359
tccttcatta agctgaataa taatggcttt gaagatattg tcattgttat agatcctagt       60

gtgccagaag atgaaaaaat aattgaacaa atagaggata tggtgactac agcttctacg      120

tacctgtttg aagccacaga aaaaagattt tttttcaaaa atgtatctat attaattcct      180

gagaattgga aggaaaatcc tcagtacaaa aggccaaaac atgaaaacca taaacatgct      240

gatgttatag ttgcaccacc tacactccca ggtagagatg aaccatacac caagcagttc      300

acagaatgtg gagagaaagg cgaatacatt cacttcaccc ctgaccttct acttggaaaa      360

aaacaaaatg aatatggacc accaggcaaa ctgtttgtcc atgagtgggc tcacctccgg      420

tggggagtgt ttgatgagta caatgaagat cagcctttct accgtgctaa gtcaaaaaaa      480

atcgaagcaa caaggtgttc cgcaggtatc tctggtagaa atagagttta taagtgtcaa      540

ggaggcagct gtcttagtag agcatgcaga attgattcta caacaaaact gtatggaaaa      600

gattgtcaat tctttcctga taaagtacaa acagaaaaag catccataat gtttatgcaa      660

agtattgatt ctgttgttga attttgtaac gaaaaaaccc ataatcaaga agctccaagc      720

ctacaaaaca taaagtgcaa ttttagaagt acatgggagg tgattagcaa ttctgaggat      780

tttaaaaaca ccatacccat ggtgacacca cctcctccac ctgtcttctc attgctgaag      840

atcagtcaaa gaattgtgtg cttagttctt gataagtctg gaagcatggg gggtaaggac      900

cgcctaaatc gaatgaatca agcagcaaaa catttcctgc tgcagactgt tgaaaatgga      960

tcctgggtgg ggatggttca ctttgatagt actgccacta ttgtaaataa gctaatccaa     1020

ataaaaagca gtgatgaaag aaacacactc atggcaggat tacctacata tcctctggga     1080

ggaacttcca tctgctctgg aattaaatat gcatttcagg tgattggaga gctacattcc     1140

caactcgatg gatccgaagt actgctgctg actgatgggg aggataacac tgcaagttct     1200

tgtattgatg aagtgaaaca aagtggggcc attgttcatt ttattgcttt gggaagagct     1260

gctgatgaag cagtaataga gatgagcaag ataacaggag gaagtcattt ttatgtttca     1320

gatgaagctc agaacaatgg cctcattgat gcttttgggg ctcttacatc aggaaatact     1380

gatctctccc agaagtccct tcagctcgaa agtaagggat taacactgaa tagtaatgcc     1440

tggatgaacg acactgtcat aattgatagt acagtgggaa aggacacgtt ctttctcatc     1500

acatggaaca gtctgcctcc cagtatttct ctctgggatc ccagtggaac aataatggaa     1560

aatttcacag tggatgcaac ttccaaaatg gcctatctca gtattccagg aactgcaaag     1620

gtgggcactt gggcatacaa tcttcaagcc aaagcgaacc cagaaacatt aactattaca     1680

gtaacttctc gagcagcaaa ttcttctgtg cctccaatca cagtgaatgc taaaatgaat     1740

aaggacgtaa acagtttccc cagcccaatg attgtttacg cagaaattct acaaggatat     1800

gtacctgttc ttggagccaa tgtgactgct ttcattgaat cacagaatgg acatacagaa     1860

gttttggaac ttttggataa tggtgcaggc gctgattctt tcaagaatga tggagtctac     1920

tccaggtatt ttacagcata tacagaaaat ggcagatata gcttaaaagt tcgggctcat     1980

ggaggagcaa acactgccag gctaaaatta cggcctccac tgaatagagc cgcgtacata     2040

ccaggctggg tagtgaacgg ggaaattgaa gcaaacccgc caagacctga aattgatgag     2100

gatactcaga ccaccttgga ggatttcagc cgaacagcat ccggaggtgc atttgtggta     2160

tcacaagtcc caagccttcc cttgcctgac caatacccac caagtcaaat cacagacctt     2220

gatgccacag ttcatgagga taagattatt cttacatgga cagcaccagg agataatttt     2280

gatgttggaa aagttcaacg ttatatcata agaataagtg caagtattct tgatctaaga     2340

gacagttttg atgatgctct tcaactaaat actactgatc tgtcaccaaa ggaggccaac     2400

tccaaggaaa gctttgcatt taaaccagaa aatatctcag aagaaaatgc aacccacata     2460

tttattgcca ttaaaagtat agataaaagc aatttgacat caaaagtatc caacattgca     2520

caagtaactt tgtttatccc tcaagcaaat cctgatgaca ttgatcctac acctactcct     2580

actcctactc ctgataaaag tcataattct gga                                  2613


<210>  3360
<211>  531
<212>  DNA
<213>  Homo Sapiens

<400>  3360
tgtttggtga ctcatcacaa cttttcacgc tgtaagagag gcacaggagt gcacaagtta       60

gagcaccatg caaagctcaa atgcatcaaa gagaaatcag aactgaaaag tgctgaaggg      120

agcacctgga actgttgtcc tattgactgg agagccttcc agtccaactg ctattttcct      180

cttactgaca acaagacgtg ggctgagagt gaaaggaact gttcagggat gggggcccat      240

ctgatgacca tcagcacgga agctgagcag aactttatta ttcagtttct ggatagacgg      300

ctttcctatt tccttggact tagagatgag aatgccaaag gtcagtggcg ttgggtggac      360

cagacgccat ttaacccacg cagagtattc tggcataaga atgaacccga caactctcag      420

ggagaaaact gtgttgttct tgtttataac caagataaat gggcctggaa tgatgttcct      480

tgtaactttg aagcaagtag gatttgtaaa atacctggaa caacattgaa c               531


<210>  3361
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  3361
caaaattcca aatttcagag ggacctggtg accctgagaa cagattttag caacttcacc       60

tcaaacactg tggcggagat ccaggcactg acttcccagg gcagcagctt ggaagaaacg      120

atagcatctc tgaaagctga ggtggagggt ttcaagcagg aacggcaggc aggggtatct      180

gagctccagg aacacactac gcagaaggca cacctaggcc actgtcccca ctgcccatct      240

gtgtgtgtcc cagttcattc tgaaatgctc ctgcgagtcc agcagctggt gcaagacctg      300

aagaaactga cctgccaggt ggctactctc aacaacaatg cctccactga agggacctgc      360

tgccctgtca actgggtgga gcaccaagac agctgctact ggttctctca ctctgggatg      420

tcctgggccg aggctgagaa gtactgccag ctgaagaacg cccacctggt ggtcatcaac      480

tccagggagg agcagaattt tgtccagaaa tatctgggct ccgcatacac ctggatgggc      540

ctcagtgacc ctgaaggagc ctggaagtgg gtggatggaa cagactatgc gaccggcttc      600

cagaactgga agccaggcca gccagacgac tggcaggggc acgggctggg tggaggcgag      660

gactgtgctc acttccatcc agacggcagg tggaatgacg acgtctgcca gaggccctac      720

cactgggtct gcgaggctgg cctgggtcag accagccagg agagtcac                   768


<210>  3362
<211>  906
<212>  DNA
<213>  Homo Sapiens

<400>  3362
gctcggggag cagagaggga gtgggaggga ggctggggag gtgcccagga ggaggagcgg       60

gagagggagg ccctgatgct gaagcatctg caggaagccc taggactgcc tgctgggagg      120

ggggatgaga atcctgccgg aactgttgag ggaaaagagg actgggagat ggaggaggac      180

cagggggagg aagaggagga ggaagcaacg ccaaccccat cctccggccc cagcccctct      240

cccacccctg aggacatcgt cacttacatc ctgggccgcc tggccggcct ggacgcaggc      300

ctgcaccagc tgcacgtccg tctgcacgcg ttggacaccc gcgtggtcga gctgacccag      360

gggctgcggc agctgcggaa cgcggcaggc gacacccgcg atgccgtgca agccctgcag      420

gaggcgcagg gtcgcgccga gcgcgagcac ggccgcttgg agggctgcct gaaggggctg      480

cgcctgggcc acaagtgctt cctgctctcg cgcgacttcg aagctcaggc ggcggcgcag      540

gcgcggtgca cggcgcgggg cgggagcctg gcgcagccgg cagaccgcca gcagatggag      600

gcgctcactc ggtacctgcg cgcggcgctc gctccctaca actggcccgt gtggctgggc      660

gtgcacgatc ggcgcgccga gggcctctac ctcttcgaaa acggccagcg cgtgtccttc      720

ttcgcctggc atcgctcacc ccgccccgag ctcggcgccc agcccagcgc ctcgccgcat      780

ccgctcagcc cggaccagcc caacggtggc acgctcgaga actgcgtggc gcaggcctct      840

gacgacggct cctggtggga ccacgactgc cagcggcgtc tctactacgt ctgcgagttc      900

cccttc                                                                 906


<210>  3363
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  3363
cacgtaactt tgaagataga aatgaaaaaa atgaacaaac tacaaaacat cagtgaagag       60

ctccagagaa atatttctct acaactgatg agtaacatga atatctccaa caagatcagg      120

aacctctcca ccacactgca aacaatagcc accaaattat gtcgtgagct atatagcaaa      180

gaacaagagc acaaatgtaa gccttgtcca aggagatgga tttggcataa ggacagctgt      240

tatttcctaa gtgatgatgt ccaaacatgg caggagagta aaatggcctg tgctgctcag      300

aatgccagcc tgttgaagat aaacaacaaa aatgcattgg aatttataaa atcccagagt      360

agatcatatg actattggct gggattatct cctgaagaag attccactcg tggtatgaga      420

gtggataata taatcaactc ctctgcctgg gttataagaa acgcacctga cttaaataac      480

atgtattgtg gatatataaa tagactatat gttcaatatt atcactgcac ttataaacaa      540

agaatgatat gtgagaagat ggccaatcca gtgcagcttg gttctacata ttttagggag      600

gca                                                                    603


<210>  3364
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  3364
ttgcagatat ctaatgacat taactcagat tcagagaaat tgagtcaact tcagaaaacc       60

atccaacagc agcaggataa cttatcccag caactgggca actccaacaa cttgtccatg      120

gaggaggaat ttctcaagtc acagatctcc agtctactga agaggcagga acaaatggcc      180

atcaaactgt gccaagagct aatcattcat acttcagacc acagatgtaa tccatgtcct      240

aagatgtggc aatggtacca aaatagttgc tactatttta caacaaatga ggagaaaacc      300

tgggctaaca gtagaaagga ctgcatagac aagaactcca ccctagtgaa gatagacagt      360

ttggaagaaa aggattttct tatgtcacag ccattactca tgttttcgtt cttttggctg      420

ggattatcat gggactcctc tggcagaagt tggttctggg aagatggctc tgttccctct      480

ccatccttgt acgtctctaa ctat                                             504


<210>  3365
<211>  1059
<212>  DNA
<213>  Homo Sapiens

<400>  3365
atgaagcggc aggcggccga ggaggcctgc atcctgcgag gtggggcgct cagcaccgtg       60

cgtgcgggcg ccgagctgcg cgctgtgctc gcgctcctgc gggcaggccc agggcccgga      120

gggggctcca aagacctgct gttctgggtc gcactggagc gcaggcgttc ccactgcacc      180

ctggagaacg agcctttgcg gggtttctcc tggctgtcct ccgaccccgg cggtctcgaa      240

agcgacacgc tgcagtgggt ggaggagccc caacgctcct gcaccgcgcg gagatgcgcg      300

gtactccagg ccaccggtgg ggtcgagccc gcaggctgga aggagatgcg atgccacctg      360

cgcgccaacg gctacctgtg caagtaccag tttgaggtct tgtgtcctgc gccgcgcccc      420

ggggccgcct ctaacttgag ctatcgcgcg cccttccagc tgcacagcgc cgctctggac      480

ttcagtccac ctgggaccga ggtgagtgcg ctctgccggg gacagctccc gatctcagtt      540

acttgcatcg cggacgaaat cggcgctcgc tgggacaaac tctcgggcga tgtgttgtgt      600

ccctgccccg ggaggtacct ccgtgctggc aaatgcgcag agctccctaa ctgcctagac      660

gacttgggag gctttgcctg cgaatgtgct acgggcttcg agctggggaa ggacggccgc      720

tcttgtgtga ccagtgggga aggacagccg acccttgggg ggaccggggt gcccaccagg      780

cgcccgccgg ccactgcaac cagccccgtg ccgcagagaa catggccaat cagggtcgac      840

gagaagctgg gagagacacc acttgtccct gaacaagaca attcagtaac atctattcct      900

gagattcctc gatggggatc acagagcacg atgtctaccc ttcaaatgtc ccttcaagcc      960

gagtcaaagg ccactatcac cccatcaggg agcgtgattt ccaagtttaa ttctacgact     1020

tcctctgcca ctcctcaggc tttcgactcc tcctctgcc                            1059


<210>  3366
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  3366
aagtaccagg agttgatgga agaactgaga atgttaagct ttcagcagat gacgtggcga       60

acaaatatga ctggcatggc agggctagct ggcctgaagc atgacattgc ccgtgtaaga      120

gctgacacca accagtccct ggtggaactt tggggcttat tagactgccg ccgaattacc      180

tgtcctgaag gctggctgcc ctttgagggc aagtgttact acttctcccc aagcaccaag      240

tcatgggatg aggcccggat gttctgccag gagaattact ctcacttggt catcatcaat      300

agctttgctg agcacaattt tgtggccaag gcccatggct ctccacgggt gtactggctg      360

gggctgaatg acagggccca ggaaggggac tggaggtggc tggatgggtc tcctgtgaca      420

ttaagcttct gggagccaga ggaacccaat aacatccacg atgaggactg tgctaccatg      480

aacaaaggtg gcacctggaa tgatctctct tgctacaaaa ctacgtattg gatttgtgag      540

cggaaatgtt cctgt                                                       555


<210>  3367
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3367
gaggtgtggc caccccagct gcaggagcag gctccgatgg ccggagccct gaacaggaag       60

gagagtttct tgctcctctc cctgcacaac cgcctgcgca gctgggtcca gccccctgcg      120

gctgacatgc ggaggctgga ctggagtgac agcctggccc agctggctca agccagggca      180

gccctctgtg gaaccccaac cccgagcctg gcgtccggcc tgtggcgcac cctgcaagtg      240

ggctggaaca tgcagctgct acccgcgggc ttggtgtcct ttgtcgaagt ggtcagccta      300

tggtttgcag aggggcagcg gtacagccac gcggcaggag agtgtgctcg caacgccacc      360

tgcacccact acacgcagct cgtgtgggcc acctcaagcc agctgggctg tgggcggcac      420

ctgtgctctg caggccaggc agcgatagaa gcctttgtct gtgcctactc ccccagaggc      480

aactgggagg tcaacgggaa gacaatcgtc ccctataaga agggtgcctg gtgttcgctc      540

tgcacagcca gtgtctcagg ctgcttcaaa gcctgggacc atgcaggggg gctctgtgag      600

gtccccagga atccttgtcg catgagctgc cagaaccatg gacgtctcaa catcagcacc      660

tgccactgcc actgtccccc tggctacacg ggcagatact gccaagtgag gtgcagcctg      720

cagtgtgtgc acggccggct ccgggaggag gagtgctcgt gcgtctgtga catcggctac      780

gggggagccc agtgtgccac caaggtgcat tttcccttcc acacctgtga cctgaggatc      840

gacggagact gcttcatggt gtcttcagag gcagacacct attacagagc caggatgaaa      900

tgtcagagga aaggcggggt gctggcccag atcaagagcc agaaagtgca ggacatcctc      960

gccttctatc tgggccgcct ggagaccacc aacgaggtga ttgacagtga cttcgagacc     1020

aggaacttct ggatcgggct cacctacaag accgccaagg actccttccg ctgggccaca     1080

ggggagcacc aggccttcac cagttttgcc tttgggcagc ctgacaacca cgggtttggc     1140

aactgcgtgg agctgcaggc ttcagctgcc ttcaactgga acaaccagcg ctgcaaaacc     1200

cgaaaccgtt acatctgcca gtttgcccag gagcacatct cccggtgggg cccagggtcc     1260


<210>  3368
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3368
gaggtgtggc caccccagct gcaggagcag gctccgatgg ccggagccct gaacaggaag       60

gagagtttct tgctcctctc cctgcacaac cgcctgcgca gctgggtcca gccccctgcg      120

gctgacatgc ggaggctgga ctggagtgac agcctggccc agctggctca agccagggca      180

gccctctgtg gaaccccaac cccgagcctg gcgtccggcc tgtggcgcac cctgcaagtg      240

ggctggaaca tgcagctgct acccgcgggc ttggcgtcct ttgtcgaagt ggtcagccta      300

tggtttgcag aggggcagcg gtacagccac gcggcaggag agtgtgctcg caacgccacc      360

tgcacccact acatgcagct cgtgtgggcc acctcaagcc agctgggctg tgggcggcac      420

ctgtgctctg caggccaggc agcgatagaa gcctttgtct gtgcctactc ccccagaggc      480

aactgggagg tcaacgggaa gacaatcgtc ccctataaga agggtgcctg gtgttcgctc      540

tgcacagcca gtgtctcagg ctgcttcaaa gcctgggacc atgcaggggg gctctgtgag      600

gtccccagga atccttgtcg catgagctgc cagaaccatg gacgtctcaa catcagcacc      660

tgccactgcc actgtccccc tggctacacg ggcagatact gccaagtgag gtgcagcctg      720

cagtgtgtgc acggccggtt ccgggaggag gagtgctcgt gcgtctgtga catcggctac      780

gggggagccc agtgtgccac caaggtgcat tttcccttcc acacctgtga cctgaggatc      840

gacggagact gcttcatggt gtcttcagag gcagacacct attacagagc caggatgaaa      900

tgtcagagga aaggcggggt gctggcccag atcaagagac agaaagtgca ggacatcctc      960

gccttctatc tgggccgcct ggagaccacc aacgaggtga ttgacagtga cttcgagacc     1020

aggaacttct ggatcgggct cacctacaag accgccaagg actccttccg ctgggccaca     1080

ggggagcacc aggccttcac cagttttgcc tttgggcagc ctgacaacca cgggtttggc     1140

aactgcgtgg agctgcaggc ttcagctgcc ttcaactgga acgaccagcg ctgcaaaacc     1200

cgaaaccgtt acatctgcca gtttgcccag gagcacatct cccggtgggg cccagggtcc     1260


<210>  3369
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  3369
tttccacaaa cagacatcag tatcagtcca gccctgccag agctgcccct gccttccctg       60

tgccccctgt tctggatgga gttcaaaggc cactgctatc gattcttccc tctcaataag      120

acctgggccg aggccgacct ctactgttct gagttctctg tgggcaggaa gtccgccaag      180

ctggcctcca tccacagctg ggaggagaat gtctttgtat atgacctcgt gaacagctgt      240

gttcccggca tcccagctga cgtctggaca ggccttcatg atcacagaca ggtgagaaag      300

cagtggccat tgggccccct tggaagctcc agccaggatt ctattttgat t               351


<210>  3370
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3370
cagtactacc agctctccaa tactggtcaa gacaccattt ctcaaatgga agaaagatta       60

ggaaatacgt cccaagagtt gcaatctctt caagtccaga atataaagct tgcaggaagt      120

ctgcagcatg tggctgaaaa actctgtcgt gagctgtata acaaagctgg agcacacagg      180

tgcagccctt gtacagaaca atggaaatgg catggagaca attgctacca gttctataaa      240

gacagcaaaa gttgggagga ctgtaaatat ttctgcctta gtgaaaactc taccatgctg      300

aagataaaca aacaagaaga cctggaattt gccgcgtctc agagctactc tgagtttttc      360

tactcttatt ggacagggct tttgcgccct gacagtggca aggcctggct gtggatggat      420

ggaacccctt tcacttctga actgttccat attataatag atgtcaccag cccaagaagc      480

agagactgtg tggccatcct taatgggatg atcttctcaa aggactgcaa agaattgaag      540

cgttgtgtct gtgagagaag ggcaggaatg gtgaagccag agagcctcca tgtcccccct      600

gaaacattag gcgaaggtga c                                                621


<210>  3371
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3371
gctgtcatgc agcgcaatta cctacaagat gagaatgaaa atcgcacagg aactctgcaa       60

caattagcaa agcgcttctg tcaatatgtg gtaaaacaat cagaactaaa gggcactttc      120

aaaggtcata aatgcagccc ctgtgacaca aactggagat attatggaga tagctgctat      180

gggttcttca ggcacaactt aacatgggaa gagagtaagc agtactgcac tgacatgaat      240

gctactctcc tgaagattga caaccggaac attgtggagt acatcaaagc caggactcat      300

ttaattcgtt gggtcggatt atctcgccag aagtcgaatg aggtctggaa gtgggaggat      360

ggctcggtta tctcagaaaa tatgtttgag tttttggaag atggaaaagg aaatatgaat      420

tgtgcttatt ttcataatgg gaaaatgcac cctaccttct gtgagaacaa acattattta      480

atgtgtgaga ggaaggctgg catgaccaag gtggaccaac tacct                      525


<210>  3372
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  3372
aaactaactc gagattctca gagtttatgc ccctatgatt ggattggttt ccaaaacaaa       60

tgctattatt tctctaaaga agaaggagat tggaattcaa gtaaatacaa ctgttccact      120

caacatgccg acctaactat aattgacaac atagaagaaa cgaattttct taggcggtat      180

aaatgcagtt ctgatcactg gattggactg aagatggcaa aaaatcgaac aggacaatgg      240

gtagatggag ctacatttac caaatcgttt ggcatgagag ggagtgaagg atgtgcctac      300

ctcagcgatg atggtgcagc aacagctaga tgttacaccg aaagaaaatg gatttgcagg      360

aaaagaatac ac                                                          372


<210>  3373
<211>  285
<212>  DNA
<213>  Homo Sapiens

<400>  3373
agagctaact gccatcaaga gccatcagta tgtcttcaag ctgcatgccc agaaagctgg       60

attggttttc aaagaaagtg tttctatttt tctgatgaca ccaagaactg gacatcaagt      120

cagaggtttt gtgactcaca agatgctgat cttgctcagg ttgaaagctt ccaggaactg      180

aatttcctgt tgagatataa aggcccatct gatcactgga ttgggctgag cagagaacaa      240

ggccaaccat ggaaatggat aaatggtact gaatggacaa gacag                      285


<210>  3374
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3374
cacacatcca gattaaaagc caggaagcac agcaaacgtc gagtgagaga caaggatgga       60

gatctgaaga ctcaaattga aaagctctgg acagaagtca atgccttgaa ggaaattcaa      120

gccctgcaga cagtctgtct ccgaggcact aaagttcaca agaaatgcta ccttgcttca      180

gaaggtttga agcatttcca tgaggccaat gaagactgca tttccaaagg aggaatcctg      240

gttatcccca ggaactccga cgaaatcaac gccctccaag actatggtaa aaggagcctg      300

ccaggtgtca atgacttttg gctgggcatc aatgacatgg tcacggaagg caagtttgtt      360

gacgtcaacg gaatcgctat ctccttcctc aactgggacc gtgcacagcc taacggtggc      420

aagcgagaaa actgtgtcct gttctcccaa tcagctcagg gcaagtggag tgatgaggcc      480

tgtcgcagca gcaagagata catatgcgag ttcaccatcc ctcaa                      525


<210>  3375
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  3375
caaaaatatt ctcagcttct tgaaaaaaag actacaaaag agctggttca tacaacattg       60

gagtgtgtga aaaaaaatat gcccgtggaa gagacagcct ggagctgttg cccaaagaat      120

tggaagtcat ttagttccaa ctgctacttt atttctactg aatcagcatc ttggcaagac      180

agtgagaagg actgtgctag aatggaggct cacctgctgg tgataaacac tcaagaagag      240

caggatttca tcttccagaa tctgcaagaa gaatctgctt attttgtggg gctctcagat      300

ccagaaggtc agcgacattg gcaatgggtt gatcagacac catacaatga aagttccaca      360

ttctggcatc cacgtgagcc cagtgatccc aatgagcgct gcgttgtgct aaattttcgt      420

aaatcaccca aaagatgggg ctggaatgat gttaattgtc ttggtcctca aaggtcagtt      480

tgtgagatga tgaagatcca ctta                                             504


<210>  3376
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  3376
aattttatgt atagcaaaac tgtcaagagg ctgtccaagt tacgagagta tcaacagtat       60

catccaagcc tgacctgcgt catggaagga aaggacatag aagattggag ctgctgccca      120

accccttgga cttcatttca gtctagttgc tactttattt ctactgggat gcaatcttgg      180

actaagagtc aaaagaactg ttctgtgatg ggggctgatc tggtggtgat caacaccagg      240

gaagaacagg atttcatcat tcagaatctg aaaagaaatt cttcttattt tctggggctg      300

tcagatccag ggggtcggcg acattggcaa tgggttgacc agacaccata caatgaaaat      360

gtcacattct ggcactcagg tgaacccaat aaccttgatg agcgttgtgc gataataaat      420

ttccgttctt cagaagaatg gggctggaat gacattcact gtcatgtacc tcagaagtca      480

atttgcaaga tgaagaagat ctacata                                          507


<210>  3377
<211>  537
<212>  DNA
<213>  Homo Sapiens

<400>  3377
agatgtgttg tgacatttcg catctttcaa acctgtgatg agaaaaagtt tcagctacct       60

gagaatttca cagagctctc ctgctacaat tatggatcag gttcagtcaa gaattgttgt      120

ccattgaact gggaatattt tcaatccagc tgctacttct tttctactga caccatttcc      180

tgggcgttaa gtttaaagaa ctgctcagcc atgggggctc acctggtggt tatcaactca      240

caggaggagc aggaattcct ttcctacaag aaacctaaaa tgagagagtt ttttattgga      300

ctgtcagacc aggttgtcga gggtcagtgg caatgggtgg acggcacacc tttgacaaag      360

tctctgagct tctgggatgt aggggagccc aacaacatag ctaccctgga ggactgtgcc      420

accatgagag actcttcaaa cccaaggcaa aattggaatg atgtaacctg tttcctcaat      480

tattttcgga tttgtgaaat ggtaggaata aatcctttga acaaaggaaa atctctt         537


<210>  3378
<211>  1521
<212>  DNA
<213>  Homo Sapiens

<400>  3378
caacagcaga caagacctgt tccgaagcct gtgcaagccg taattctggg agacaacatt       60

actgggcatt taccttttga acccaacaat catcaccact ttggcaggga ggcagaaatg      120

cgagagctta tccagacatt taaaggccac atggagaatt ccagtgcctg ggtagtagaa      180

atccagatgt tgaagtgcag agtggacaat gtcaattcgc agctccaggt gctcggtgat      240

catctgggaa acaccaatgc tgacatccag atggtaaaag gagttctaaa ggatgccact      300

acattgagtt tgcagacaca gatgttaagg agttccctgg agggaaccaa tgctgagatc      360

cagaggctca aggaagacct tgaaaaggca gatgctttaa ctttccagac gctgaatttc      420

ttaaaaagca gtttagaaaa caccagcatt gagctccacg tgctaagcag aggcttagaa      480

aatgcaaact ctgaaattca gatgttgaat gccagtttgg aaacggcaaa tacccaggct      540

cagttagcca atagcagttt aaagaacgct aatgctgaga tctatgtttt gagaggccat      600

ctagatagtg tcaatgactt gaggacccag aaccaggttt taagaaatag tttggaagga      660

gccaatgctg agatccaggg actaaaggaa aatttgcaga acacaaatgc tttaaactcc      720

cagacccagg cctttataaa aagcagtttt gacaacacta gtgctgagat ccagttctta      780

agaggtcatt tggaaagagc tggtgatgaa attcacgtgt taaaaaggga tttgaaaatg      840

gtcacagccc agacccaaaa agcaaatggc cgtctggacc agacagatac tcagattcag      900

gtattcaagt cagagatgga aaatgtgaat accttaaatg cccagattca ggtcttaaat      960

ggtcatatga aaaatgccag cagagagata cagaccctaa aacaaggaat gaagaatgct     1020

tcagccttaa cttcccagac ccagatgtta gacagcaatc tgcagaaggc cagtgccgag     1080

atccagaggt taagagggga tctagagaac accaaagctc taaccatgga aatccagcag     1140

gagcagagtc gcctgaagac cctccatgtg gtcattactt cacaggaaca gctacaaaga     1200

acccaaagtc agcttctcca gatggtcctg caaggctgga agttcaatgg tggaagctta     1260

tattattttt ctagtgtcaa gaagtcttgg catgaggctg agcagttctg cgtgtcccag     1320

ggagcccatc tggcatctgt ggcctccaag gaggagcagg catttctggt agagttcaca     1380

agtaaagtgt actactggat cggtctcact gacaggggca cagagggctc ctggcgctgg     1440

acagatggga caccattcaa cgccgcccag aacaaagcga gccacagcac caggaaggga     1500

tgctgccttc atctaacagt a                                               1521


<210>  3379
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  3379
ttgtccaagg cctccacgga gcgcgcggcg ctgcttgacg gccacgacct gctgaggaca       60

aacgcctcga agcagacggc ggcgctgggt gccctgaagg aggaggtcgg agactgccac      120

agctgctgct cggggacgca ggcgcagctg cagaccacgc gcgcggagct tggggaggcg      180

caggcgaagc tgatggagca ggagagcgcc ctgcgggaac tgcgtgagcg cgtgacccag      240

ggcttggctg aagccggcag gggccgtgag gacgtccgca ctgagctgtt ccgggcgctg      300

gaggccgtga ggctccagaa caactcctgc gagccgtgcc ccacgtcgtg gctgtccttc      360

gagggctcct gctacttttt ctctgtgcca aagacgacgt gggcggcggc gcaggatcac      420

tgcgcagatg ccagcgcgca cctggtgatc gttgggggcc tggatgagca gggcttcctc      480

actcggaaca cgcgtggccg tggttactgg ctgggcctga gggctgtgcg ccatctgggc      540

aaggttcagg gctaccagtg ggtggacgga gtctctctca gcttcagcca ctggaaccag      600

ggagagccca atgacgcttg ggggcgcgag aactgtgtca tgatgctgca cacggggctg      660

tggaacgacg caccgtgtga cagcgagaag gacggctgga tctgtgagaa aaggcacaac      720

tgc                                                                    723


<210>  3380
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  3380
caagtgtcca aggtccccag ctccctaagt caggaacaat ccgagcaaga cgcaatctac       60

cagaacctga cccagcttaa agctgcagtg ggtgagctct cagagaaatc caagctgcag      120

gagatctacc aggagctgac ccagctgaag gctgcagtgg gtgagttgcc agagaaatcc      180

aagctgcagg agatctacca ggagctgacc cggctgaagg ctgcagtggg tgagttgcca      240

gagaaatcca agctgcagga gatctaccag gagctgaccc ggctgaaggc tgcagtgggt      300

gagttgccag agaaatccaa gctgcaggag atctaccagg agctgacccg gctgaaggct      360

gcagtgggtg agttgccaga gaaatccaag ctgcaggaga tctaccagga gctgacggag      420

ctgaaggctg cagtgggtga gttgccagag aaatccaagc tgcaggagat ctaccaggag      480

ctgacccagc tgaaggctgc agtgggtgag ttgccagacc agtccaagca gcagcaaatc      540

tatcaagaac tgaccgattt gaagactgca tttgaacgcc tgtgccgcca ctgtcccaag      600

gactggacat tcttccaagg aaactgttac ttcatgtcta actcccagcg gaactggcac      660

gactccgtca ccgcctgcca ggaagtgagg gcccagctcg tcgtaatcaa aactgctgag      720

gagcagaact tcctacagct gcagacttcc aggagtaacc gcttctcctg gatgggactt      780

tcagacctaa atcaggaagg cacgtggcaa tgggtggacg gctcacctct gtcacccagc      840

ttccagcggt actggaacag tggagaaccc aacaatagcg ggaatgaaga ctgtgcggaa      900

tttagtggca gtggctggaa cgacaatcga tgtgacgttg acaattactg gatctgcaaa      960

aagcccgcag cctgcttcag agacgaa                                          987


<210>  3381
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  3381
ccacagattt ttaacaaaag taacgatggt ttcaccacca ccaggagcta tggaacagtc       60

tcacagattt ttgggagcag ttccccaagt cccaacggct tcattaccac aaggagctat      120

ggaacagtct gccccaaaga ctgggaattt tatcaagcaa gatgtttttt cttatccact      180

tctgaatcat cttggaatga aagcagggac ttttgcaaag gaaaaggatc cacattggca      240

attgtcaaca cgccagagaa actgaagttt cttcaggaca taactgatgc tgagaagtat      300

tttattggct taatttacca tcgtgaagag aaaaggtggc gttggatcaa caactctgtg      360

ttcaatggca atgttaccaa tcagaatcag aatttcaact gtgcgaccat tggcctaaca      420

aagacatttg atgctgcatc atgtgacatc agctaccgca ggatctgtga gaagaatgcc      480

aaa                                                                    483


<210>  3382
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  3382
acttaccatt ttacatatgg tgaaactggc aaaaggctgt ctgaactaca ctcatatcat       60

tcaagtctca cctgcttcag tgaagggaca aaggtgccag cctggggatg ttgcccagct      120

tcttggaagt catttggttc cagttgctac ttcatttcca gtgaagagaa ggtttggtct      180

aagagtgagc agaactgtgt tgagatggga gcacatttgg ttgtgttcaa cacagaagca      240

gagcagaatt tcattgtcca gcagctgaat gagtcatttt cttattttct ggggctttca      300

gacccacaag gtaataataa ttggcaatgg attgataaga caccttatga gaaaaatgtc      360

agattttggc acctaggtga gcccaatcat tctgcagagc aatgtgcttc aatagtcttc      420

tggaaaccta caggatgggg ctggaatgat gttatctgtg aaactagaag gaattcaata      480

tgtgagatga ataagattta ccta                                             504


<210>  3383
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  3383
accatggggg ttctttccag cccttgtcct cctaattgga ttatatatga gaagagctgt       60

tatctattca gcatgtcact aaattcctgg gatggaagta aaagacaatg ctggcaactg      120

ggctctaatc tcctaaagat agacagctca aatgaattgg taagtgtaga cttctgttat      180

gattatctgt ggtgtgtatc c                                                201


<210>  3384
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  3384
aaattattgc aggtttccac tatagctatg caacaacaag aaaaattgat acagcaggag       60

agagcacttc ttaatttcac cgagtggaag cgttcatgcg ccttacagat gaaatattgt      120

caagcgttta tgcagaacag cttatcatcc gcccataatt caagtccgtg ccctaataac      180

tggatacaga atagggaatc atgctactat gtttctgaga tatggtccat ttggcatacc      240

agtcaagaaa attgtcttaa agaggggtca acactacttc agatagagag caaggaggag      300

atggatttca ttacaggatc cctaaggaaa atcaaaggta gttacgatta ttgggtcggc      360

ctgtcccagg atgggcactc agggagatgg ctatggcaag acggaagtag ccctagcccc      420

ggtctattgc ccgccgagag gtctcagtct gcgaatcagg tttgcggcta tgttaaaagt      480

aattccctac tgagttcaaa ttgctcaact tggaagtact tcatatgtga aaaatacgct      540

ttaagatcat ctgtg                                                       555


<210>  3385
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  3385
aaaactgttc ggacttcccc gttagaactc gcgtttccac ttcagagatc tgtttctttc       60

aacttttcta ctgtccataa atcatgtcct gccaaagact ggaaggtgca taagggaaaa      120

tgttactgga ttgctgaaac taagaaatct tggaacaaaa gtcaaaatga ctgtgccata      180

aacaattcat atctcatggt gattcaagac attactgcta tggtgagatt taacatt         237


<210>  3386
<211>  960
<212>  DNA
<213>  Homo Sapiens

<400>  3386
cagagacaca gtccacagga ggcaccccat gtgcagtacg agcgcctggg ctctgacgtg       60

acactgccat gtgggacagc aaactgggat gctgcggtga cgtggcgggt aaatgggaca      120

gacctggccc ctgacctgct caacggctct cagctggtgc tccatggcct ggaactgggc      180

cacagtggcc tctacgcctg cttccaccgt gactcctggc acctgcgcca ccaagtcctg      240

ctgcatgtgg gcttgccgcc gcgggagcct gtgctcagct gccgctccaa cacttacccc      300

aagggcttct actgcagctg gcatctgccc acccccacct acattcccaa caccttcaat      360

gtgactgtgc tgcatggctc caaaattatg gtctgtgaga aggacccagc cctcaagaac      420

cgctgccaca ttcgctacat gcacctgttc tccaccatca agtacaaggt ctccataagt      480

gtcagcaatg ccctgggcca caatgccaca gctatcacct ttgacgagtt caccattgtg      540

aagcctgatc ctccagaaaa tgtggtagcc cggccagtgc ccagcaaccc tcgccggctg      600

gaggtgacgt ggcagacccc ctcgacctgg cctgaccctg agtcttttcc tctcaagttc      660

tttctgcgct accgacccct catcctggac cagtggcagc atgtggagct gtccgacggc      720

acagcacaca ccatcacaga tgcctacgcc gggaaggagt acattatcca ggtggcagcc      780

aaggacaatg agattgggac atggagtgac tggagcgtag ccgcccacgc tacgccctgg      840

actgaggaac cgcgacacct caccacggag gcccaggctg cggagaccac gaccagcacc      900

accagctccc tggcaccccc acctaccacg aagatctgtg accctgggga gctgggcagc      960


<210>  3387
<211>  1821
<212>  DNA
<213>  Homo Sapiens

<400>  3387
gagtttacat ggtatagaag atatggtcat ggagtttctg aggaagacaa aggatttgga       60

ccaatttttg aagagcagcc aatcaatacc atttatccag aggaatcact ggaaggaaaa      120

gtctcactca actgtagggc acgagccagc cctttcccgg tttacaaatg gagaatgaat      180

aatggggacg ttgatctcac aagtgatcga tacagtatgg taggaggaaa ccttgttatc      240

aacaaccctg acaaacagaa agatgctgga atatactact gtttagcatc taataactac      300

gggatggtca gaagcactga agcaaccctg agctttggat atcttgatcc tttcccacct      360

gaggaacgtc ctgaggtcag agtaaaagaa gggaaaggaa tggtgcttct ctgtgacccc      420

ccataccatt ttccagatga tcttagctat cgctggcttc taaatgaatt tcctgtattt      480

atcacaatgg ataaacggcg atttgtgtct cagacaaatg gcaatctcta cattgcaaat      540

gttgaggctt ccgacaaagg caattattcc tgctttgttt ccagtccttc tattacaaag      600

agcgtgttca gcaaattcat cccactcatt ccaatacctg aacgaacaac aaaaccatat      660

cctgctgata ttgtagttca gttcaaggat gtatatgcat tgatgggcca aaatgtgacc      720

ttagaatgtt ttgcacttgg aaatcctgtt ccggatatcc gatggcggaa ggttctagaa      780

ccaatgccaa gcactgctga gattagcacc tctggggctg ttcttaagat cttcaatatt      840

cagctagaag atgaaggcat ctatgaatgt gaggctgaga acattagagg aaaggataaa      900

catcaagcaa gaatttatgt tcaagcattc cctgagtggg tagaacacat caatgacaca      960

gaggtggaca taggcagtga tctctactgg ccttgtgtgg ccacaggaaa gcccatccct     1020

acaatccgat ggttgaaaaa tggatatgcg tatcataaag gggaattaag actgtatgat     1080

gtgacttttg aaaatgccgg aatgtatcag tgcatagctg aaaacacata tggagccatt     1140

tatgcaaatg ctgagttgaa gatcttggcg ttggctccaa cttttgaaat gaatcctatg     1200

aagaaaaaga tcctggctgc taaaggtgga agggtgataa ttgaatgcaa acctaaagct     1260

gcaccgaaac caaagttttc atggagtaaa gggacagagt ggcttgtcaa tagcagcaga     1320

atactcattt gggaagatgg tagcttggaa atcaacaaca ttacaaggaa tgatggaggt     1380

atctatacat gctttgcaga aaataacaga gggaaagcta atagcactgg aacccttgtt     1440

atcacagatc ctacgcgaat tatattggcc ccaattaatg ccgatatcac agttggagaa     1500

aacgccacca tgcagtgtgc tgcgtccttt gatcctgcct tggatctcac atttgtttgg     1560

tccttcaatg gctatgtgat cgattttaac aaagagaata ttcactacca gaggaatttt     1620

atgctggatt ccaatgggga attactaatc cgaaatgcgc agctgaaaca tgctggaaga     1680

tacacatgca ctgcccagac aattgtggac aattcttcag cttcagctga ccttgtagtg     1740

agaggtaaaa acagaaaagg tggagagaaa aacatggtgg attcctttct ccccgtctgt     1800

gcaagcctgc ctccaacctg g                                               1821


<210>  3388
<211>  2946
<212>  DNA
<213>  Homo Sapiens

<400>  3388
tcccaaacca ccttcgggcc tgtctttgaa gaccagcccc tcagtgtgct attcccagag       60

gagtccacgg aggagcaggt gttgctggca tgccgcgccc gggccagccc tccagccacc      120

tatcggtgga agatgaatgg taccgagatg aagctggagc caggttcccg tcaccagctg      180

gtggggggca acctggtcat catgaacccc accaaggcac aggatgccgg ggtctaccag      240

tgcctggcct ccaacccagt gggcaccgtt gtcagcaggg aggccatcct ccgcttcggc      300

tttctgcagg aattctccaa ggaggagcga gacccagtga aagctcatga aggctggggg      360

gtgatgttgc cctgtaaccc acctgcccac tacccaggct tgtcctaccg ctggctcctc      420

aacgagttcc ccaacttcat cccgacggac gggcgtcact tcgtgtccca gaccacaggg      480

aacctgtaca ttgcccgaac caatgcctca gacctgggca actactcctg tttggccacc      540

agccacatgg acttctccac caagagcgtc ttcagcaagt ttgctcagct caacctggct      600

gctgaagata cccggctctt tgcacccagc atcaaggccc ggttcccagc agagacctat      660

gcactggtgg ggcagcaggt caccctggag tgcttcgcct ttgggaaccc tgtcccccgg      720

atcaagtggc gcaaagtgga cggctccctg tccccgcagt ggaccacagc tgagcccacc      780

ctgcagatcc ccagcgtcag ctttgaggat gagggcacct acgagtgtga ggcggagaac      840

tccaagggcc gagacaccgt gcagggccgc atcatcgtgc aggctcagcc tgagtggcta      900

aaagtgatct cggacacaga ggctgacatt ggctccaacc tgcgttgggg ctgtgcagcc      960

gccggcaagc cccggcctac agtgcgctgg ctgcggaacg gggagcctct ggcctcccag     1020

aaccgggtgg aggtgttggc tggggacctg cggttctcca agctgagcct ggaagactcg     1080

ggcatgtacc agtgtgtggc agagaataag cacggtacca tctacgccag cgccgagcta     1140

gccgtgcaag cactcgcccc tgacttcagg ctgaatcccg tgaggcgtct gatccccgcg     1200

gcccgcgggg gagagatcct tatcccctgc cagccccggg cagctccaaa ggccgtggtg     1260

ctctggagca aaggcacgga gattttggtc aacagcagca gagtgactgt aactccagat     1320

ggcaccttga tcataagaaa catcagccgg tcagatgaag gcaaatacac ctgctttgct     1380

gagaacttca tgggcaaagc caacagcact ggaatcctat ctgtgcgaga tgcaaccaaa     1440

atcactctag ccccctcaag tgccgacatc aacttgggtg acaacctgac cctacagtgc     1500

catgcctccc acgaccccac catggacctc accttcacct ggaccctgga cgacttcccc     1560

atcgactttg ataagcctgg agggcactac cggagaacta atgtgaagga gaccattggg     1620

gatctgacca tcctgaacgc ccagctgcgc catgggggga agtacacgtg catggcccag     1680

acggtggtgg acagcgcgtc caaggaggcc acagtcctgg tccgaggtcc gccaggtccc     1740

ccaggaggtg tggtggtgag ggacattggc gacaccacca tccagctcag ctggagccgt     1800

ggcttcgaca accacagccc catcgctaag tacaccctgc aagctcgcac tccacctgca     1860

gggaagtgga agcaggttcg gaccaatcct gcaaacatcg agggcaatgc cgagactgca     1920

caggtgctgg gcctcacccc ctggatggac tatgagttcc gggtcatagc cagcaacatt     1980

ctgggcactg gggagcctag tgggccctcc agcaaaatcc ggaccaggga agcagccccc     2040

tcggtggcac cctcaggact cagcggagga ggtggagccc ccggagagct catcgtcaac     2100

tggacgccca tgtcacggga gtaccagaac ggagacggct tcggctacct gctgtccttc     2160

cgcaggcagg gcagcactca ctggcagacc gcccgggtgc ctggcgccga tgcccagtac     2220

tttgtctaca gcaacgagag cgtccggccc tacacgccct ttgaggtcaa gatccgcagc     2280

tacaaccgcc gcggggatgg gcccgagagc ctcactgcac tcgtgtactc agctgaggaa     2340

gagcccaggg tggcccctac caaggtgtgg gccaaagggg tctcatcctc agagatgaac     2400

gtgacctggg aacccgtgca gcaggacatg aatggtatcc tcctggggta tgagatccgc     2460

tactggaaag ctggggacaa agaagcagct gcggaccgag tgaggacagc agggctggac     2520

accagtgccc gagtcagcgg cctgcatccc aacaccaagt accatgtgac cgtgagggcc     2580

tacaaccggg ctggcactgg gcctgccagc ccttctgcca acgccacgac catgaagccc     2640

cctccgcggc gacctcctgg caacatctcc tggactttct caagctctag tcttagcatt     2700

aagtgggacc ctgtggtccc tttccgaaat gagtctgcag tcaccggcta taagatgctg     2760

taccagaatg acttacacct gactcccacg ctccacctca ccggcaagaa ctggatagaa     2820

atcccagtgc ctgaagacat tggccatgcc ctggtacaaa ttcggaccac agggcccgga     2880

ggggatggga tccctgcaga agtccacatc gtgaggaatg gaggcacaag catgatggtg     2940

gagaac                                                                2946


<210>  3389
<211>  2949
<212>  DNA
<213>  Homo Sapiens

<400>  3389
gagcttctct tacaaggccc tgtatttatc aaagaaccca gcaacagcat tttccctgtt       60

ggttcagaag ataaaaaaat aactttgcat tgtgaagcaa gaggcaatcc atcacctcat      120

tacagatggc agctgaatgg aagtgatatt gatatgagta tggaacatcg ttataagttg      180

aatggaggaa atcttgtggt tattaatccc aacagaaatt gggatacagg aacttaccaa      240

tgttttgcaa caaattcact tggaacaatt gtcagcagag aagccaaact tcagtttgcc      300

tatcttgaaa attttaaaac caaaatgagg agtacagtgt ctgtgcgtga aggccaggga      360

gttgtgctgc tctgcggccc cccaccacac tctggagaac tgtcatatgc ttggatcttc      420

aatgaatacc catcgtttgt tgaagaagat agtcggagat ttgtctccca ggagacaggg      480

cacctctaca tatctaaggt ggagccgtct gatgtgggaa attacacatg tgtggtgaca      540

agtatggtga caaatgcccg agtgctgggc tctccaactc ctttggtgct acgttctgat      600

ggtgtgatgg gtgaatatga acctaaaata gaagttcagt ttccagaaac tcttccagca      660

gctaaaggtt cgactgtgaa attggaatgt tttgcccttg gaaatcccat acctcagatt      720

aattggagaa gaagtgatgg gctgccattt tccagcaaaa ttaaattaag gaagttcagt      780

ggtgtgcttg aaatccccaa cttccaacag gaagatgcag gttcctatga atgcattgct      840

gagaattcac gaggaaaaaa tgttgccaga gggcgtctca cttactatgc aaagccccat      900

tgggttcaac tcataaagga tgtggaaata gccgtggagg acagtcttta ttgggaatgc      960

agggcaagcg gcaagcccaa gccttcctac cgatggctga aaaatggagc agccctggtg     1020

ctagaggaga gaacacagat agaaaatggt gcccttacaa tatcaaacct aagtgtgact     1080

gattctggca tgttccagtg catagcagaa aacaaacatg gccttgttta ttccagtgct     1140

gagctcaaag ttgttgcttc tgctccagat ttttcaaaga atccaatgaa gaagttggtt     1200

caggtgcagg tgggcagcct ggtcagcttg gattgtaaac ccagagcctc cccaagggca     1260

ctctcttcct ggaagaaggg ggatgtgagc gtgcaggagc atgaaagaat ttctttgtta     1320

aacgatggag gactcaaaat agccaatgtg actaaagctg atgctggaac ttacacctgc     1380

atggcagaaa accagtttgg gaaagcaaat ggcacaacac atttggttgt tacggaacca     1440

acaagaataa ctttggcacc atctaacatg gatgtttctg ttggtgaaag cgtcatattg     1500

ccctgccagg tacaacatga cccgctgtta gacatcatct ttacctggta tttcaatggg     1560

gcccttgcag attttaagaa agatggatct cactttgaga aagttggtgg gagttcatct     1620

ggtgatttaa tgatcagaaa cattcagctg aaacacagtg ggaaatatgt ttgtatggtg     1680

caaacggggg tggacagtgt ttcatctgct gctgacctca tagtaagagg ttcacctgga     1740

ccaccagaaa atgtgaaggt agatgaaatt acagacacaa cagcccaact ctcttggaaa     1800

gaaggtaaag acaaccatag cccagttata tcctattcta tccaggctcg gacacctttc     1860

tccgtgggtt ggcaaaccgt cacaacagtg cctgaggtca tcgatgggaa gacgcacaca     1920

gccactgtag ttgagttaaa cccatgggtg gaatatgaat ttcgggttgt agccagtaac     1980

aaaattggag gtggagaacc aagtttaccc tcagaaaaag taagaactga agaggcagtt     2040

ccagaagtgc ctccttctga agtcagtgga ggaggcggaa gccggtctga acttgtgata     2100

acctgggatc cagtccctga agaactacag aatggtgaag gttttgggta tgttgttgct     2160

ttccgccctc ttggggttac cacctggatc cagacagtgg tgacatcccc tgacacccca     2220

agatatgtct ttaggaatga aagcatcgtg ccatattcac catatgaagt taaagtgggt     2280

gtttataata acaaaggtga aggaccattt agcccagtga caacagtgtt ctctgcagaa     2340

gaagagccta cagtggcccc atctcaagtc tctgcaaata gcctatcttc ctcagaaatt     2400

gaggtttcat ggaacaccat tccttggaag ttgagcaatg gacatttact gggctatgag     2460

gtgcggtact ggaatggggg tggaaaggag gaatcatcca gtaagatgaa agtggcagga     2520

aatgagacat cagccagact acggggcctg aagagcaacc tggcctatta cacggctgtc     2580

cgggcttaca acagtgccgg cgctgggcct tttagcgcca cagttaatgt aaccaccaag     2640

aaaacgcctc ccagtcagcc accaggaaat gttgtttgga atgccacaga cactaaagtg     2700

ttacttaatt gggagcaagt taaagccatg gagaatgagt cagaagtaac aggatataaa     2760

gttttctata ggactagcag tcaaaataac gtacaagtac tgaacacaaa taaaacttca     2820

gctgaacttg tgctgcccat taaagaggac tacattattg aagtcaaggc cacaacagat     2880

ggaggggatg ggaccagtag tgaacagatc aggattccac gaataaccag tatggatgca     2940

agaggatcc                                                             2949


<210>  3390
<211>  2013
<212>  DNA
<213>  Homo Sapiens

<400>  3390
atggaagaaa atgtcttttg ggaatgtaaa gcaaatggaa ggcctaagcc tacatacaag       60

tggctaaaaa atggcgaacc tctgctaact cgggatagaa ttcaaattga gcaaggaaca      120

ctcaacataa caatagtgaa cctctcagat gctggcatgt atcagtgttt ggcagagaat      180

aaacatggag ttatcttttc caacgcagag cttagtgtta tagctgtagg tccagatttt      240

tcaagaacac tcttgaaaag agtaactctt gtcaaagtgg gaggtgaagt tgtcattgag      300

tgtaagccaa aagcgtctcc aaaacctgtt tacacctgga agaaaggaag ggatatatta      360

aaagaaaatg aaagaattac catttctgaa gatggaaacc tcagaatcat caacgttact      420

aaatcagacg ctgggagtta tacctgtata gccactaacc attttggaac tgctagcagt      480

actggaaact tggtagtgaa agatccaaca agggtaatgg tacccccttc cagtatggat      540

gtcactgttg gagagagtat tgttttaccg tgccaggtaa cgcatgatca ctcgctagac      600

atcgtgttta cttggtcatt taatggacac ctgatagact ttgacagaga tggggaccac      660

tttgaaagag ttggagggga ttcagctggt gatttgatga tccgaaacat ccaactgaag      720

catgctggga aatatgtctg catggtccaa acaagtgtgg acaggctatc tgctgctgca      780

gacctgattg taagaggtcc tccaggtccc ccagaggctg tgacaataga cgaaatcaca      840

gataccactg ctcagctctc ctggagaccc gggcctgaca atcacagccc catcaccatg      900

tatgtcattc aagccaggac tccgttctcc gtgggctggc aagcagtcag tacagtccca      960

gaactcattg atgggaagac attcacagcg accgtggtgg gtttgaaccc ttgggttgaa     1020

tatgaattcc gcacagttgc agccaacgtg attgggattg gggagcccag ccgcccctca     1080

gagaaacgga gaacagaaga agctctcccc gaagtcacac cagcgaatgt cagtggtggc     1140

ggaggcagca aatctgaact ggttataacc tgggagacgg tccctgagga attacagaat     1200

ggtcgtggct ttggttatgt ggtggccttc cggccctacg gtaaaatgat ctggatgctg     1260

acagtgctgg cctcagctga cgcctctaga tacgtgttca ggaatgagag cgtgcacccc     1320

ttctctccct ttgaggttaa agtaggtgtc ttcaacaaca aaggagaagg ccctttcagt     1380

cccaccacgg tggtgtattc tgcagaagaa gaacccacca aaccaccagc cagtatcttt     1440

gccagaagtc tttctgccac agatattgaa gttttctggg cctccccact ggagaagaat     1500

agaggacgaa tacaaggtta tgaggttaaa tattggagac atgaagacaa agaagaaaat     1560

gctagaaaaa tacgaacagt tggaaatcag acatcaacaa aaatcacgaa cttaaaaggc     1620

agtgtgctgt atcacttagc tgtcaaggca tataattctg ctgggacagg cccctctagt     1680

gcaacagtca atgtgacaac ccgaaagcca ccaccaagtc aaccccccgg aaacatcata     1740

tggaattcat cagactccaa aattatcctg aattgggatc aagtgaaggc cctggataat     1800

gagtcggaag taaaaggata caaagtcttg tacagatgga acagacaaag cagcacatct     1860

gtcattgaaa caaataaaac atcggtggag ctttctttgc ctttcgatga agattatata     1920

atagaaatta agccattcag cgacggagga gatggcagca gcagtgaaca aattcgaatt     1980

ccaaagatat caaatgccta cgcgagagga tct                                  2013


<210>  3391
<211>  3162
<212>  DNA
<213>  Homo Sapiens

<400>  3391
gagtattcaa aatctcttcc tggtctctcc acttcatatg ctgctttgtt aagaattaag       60

aagagttcat cttcatctct ctttggttcc aaaaccagac cacgatacag cagcccttca      120

ttaggaacac tgagtgcttc ttcacccagc tggctagggg cagctcagaa ttattattcc      180

cccatcaatc tttatcattc ctcagatgcc ttcaaacaag atgaaagtgt ggactatggg      240

ccagtttttg tgcaagaacc agatgatatt atttttccaa ctgattctga tgaaaagaag      300

gtagcattga attgtgaagt tcgtggcaat ccagttccca gttacagatg gcttcgaaat      360

ggaacagaaa tagatctgga aagtgattat cgctacagtt tgatagatgg caccttcatt      420

ataagcaatc caagtgaagc aaaggattct ggtcattatc agtgtttagc aaccaacact      480

gtggggagta ttcttagtag agaagctaca ctgcagtttg cctatctggg aaattttagt      540

ggccggacaa gaagtgcagt ctctgtgagg gaaggccagg gtgtcgttct gatgtgctct      600

cctccgccac attcaccaga gatcatctat agctgggtat ttaatgagtt cccttccttt      660

gtggcggaag acagccggcg gttcatctcc caggagacag gcaaccttta tatttctaaa      720

gtccaaacat cagatgttgg cagctatatt tgtctggtga aaaacacagt gacgaatgct      780

agagtcctta gtcctccaac gccactcact ctgcgtaatg atggtgtgat gggagaatat      840

gagccgaaaa ttgaggtcca ttttcctttc acggttacag ctgctaaagg aacaactgtt      900

aagatggaat gctttgcact tggcaacccc gttccaacaa tcacatggat gaaggttaat      960

ggttatattc ctagtaaggc acgtctgcgg aaatctcagg cggtgctgga aataccgaat     1020

gtacagctgg atgatgcagg catttatgag tgcagagctg aaaactcacg tggaaaaaat     1080

tcctttcgtg gacaattaca agtatacacc tacccacact gggtagaaaa actgaatgat     1140

actcagttag acagtgggag ccctctccga tgggaatgta aggctactgg aaaacccaga     1200

cccacgtatc gttggctgaa gaatggagta cccctctcac ctcagagtag ggttgagatg     1260

gttaatggag tattgatgat ccacaatgtg aatcaatcag atgctggaat gtatcagtgt     1320

ttggctgaaa ataagtatgg agccatttac gctagtgctg agctgaagat tctagcttca     1380

gctcccactt ttgcactgaa tcaactgaag aaaacaataa ttgttaccaa agaccaagaa     1440

gttgtcatag agtgcaaacc ccaaggctct ccaaaaccaa ccatctcttg gaagaaagga     1500

gacagagcag ttagagaaaa caaaagaata gctgttcttc cagacgggag tctacggatc     1560

ctaaatgctt ccaaatcaga cgagggaaag tacgtttgcc gaggggaaaa cgtctttggt     1620

tctgctgaaa ttatagcttc gctatctgta aaagaaccta caaggataga acttactcct     1680

aaaagaacag aattgacagt gggagaaagc attgtcctta attgcaaagc aattcacgat     1740

gctagtttgg atgtcacttt ctactggact ctgaaaggac agcctattga tttcgaggaa     1800

gagggtggac attttgaaag catcagggcc caagcatcct ctgcagattt aatgatcagg     1860

aacatccttc tgatgcatgc tgggagatat ggctgcaggg tacagaccac agcagacagt     1920

gtgtcagatg aggcagaact tcttgttagg ggacccccag gcccacctgg gatagtaatt     1980

gttgaggaaa taaccgaaag tacggccaca ctgtcctgga gcccagcagc tgacaaccac     2040

agcccaatct cctcctacaa ccttcaagct cgcagcccat tttccctggg ctggcaaaca     2100

gtaaagacag tcccagaaat cataacaggg gacatggagt cagccatggc tgtggaccta     2160

aatccctggg tggaatatga atttcgagtg gtagccacca accctattgg gacaggagat     2220

ccaagcaccc catctcgaat gatccgcaca aatgaagcag ttccgaagac agcacccacc     2280

aatgtaagcg gaagaagtgg aagaaggcat gagttagtca ttgcctggga gccagtatct     2340

gaagagtttc agaatgggga aggcttcggc tatattgtgg ctttcagacc caatggaaca     2400

cgtggctgga aggaaaaaat ggtgacatcc tctgaagctt ccaaattcat ttatcgagat     2460

gaaagtgtcc ctcctcttac tccctttgaa gtgaaagttg gcgtttataa caataaagga     2520

gatgggcctt ttagtcaaat tgtggtcatc tgttcagctg aaggagaacc cagtgctgct     2580

cccacagatg tcaaggcgac aagtgtgtct gtgtcagaga ttcttgttgc atggaaacac     2640

attaaagaga gtctaggaag accacaggga tttgaggttg gttactggaa agacatggaa     2700

caggaagata cagcagaaac agtcaaaact agagggaatg agtctttcgt catcctaaca     2760

ggactagaag gaaatacgtt atatcacttc acagtgaggg cttacaatgg agctggatat     2820

gggccaccta gcagtgaagt gagtgcaacc accaagaaat cccctcctag tcaagcacct     2880

agcaacctca ggtgggagca gcaaggctct caggtttctc tgggctggga acccgtcata     2940

ccattagcca acgaatctga agttgtgggt tacaaggttt tttataggca agagggtcac     3000

agcaacagcc aagttattga aacacagaaa cttcaagcag tagtaccact cccagatgct     3060

ggagtctata ttattgaagt tcgagcatat agtgaaggag gagatggaac agctagttct     3120

caaattaggg taccatcata ttcaggtgga aaaatcacaa gt                        3162


<210>  3392
<211>  2940
<212>  DNA
<213>  Homo Sapiens

<400>  3392
gatggtcttt taagccgtcc tatttttact caggagccac atgatgtcat ttttcctttg       60

gatttatcaa aatctgaggt catcctgaat tgtgctgcta acggttaccc ttcgcctcat      120

tataggtgga agcaaaatgg cacagacatt gattttacta tgagttatca ctacaggttg      180

gatggaggca gtcttgcaat caatagcccc cacacagatc aagatattgg tatgtaccag      240

tgcctggcca ccaatcttct ggggacaatt ctgagtcgga aggcaaagct ccaatttgca      300

tatattgaag actttgaaac taaaacaaga agcacagtat ctgtccgaga aggtcaaggt      360

gtggtgcttc tctgtggccc accgccacat tttggagatt tatcttatgc atggaccttc      420

aatgataacc ccttatacgt ccaagaggac aataggcgat ttgtatctca agagacggga      480

aacttgtaca ttgccaaagt ggaaccatca gatgtgggca actacacttg ctttataact      540

aacaaagagg cccagagaag tgttcaaggt ccacccactc cattagtgca gcgcactgat      600

ggtgtgatgg gggaatatga accaaagatt gaagtgcgtt ttcctgaaac tatacaagct      660

gcaaaggatt catctgtaaa actggaatgt tttgcccttg gaaatccagt ccccgatatt      720

agttggagaa ggttggacgg gagcccgttg ccagggaaag tcaagtacag caaatcccaa      780

gctatccttg aaatcccgaa cttccaacaa gaagatgaag gcttttatga gtgcattgca      840

agcaaccttc gaggaagaaa ccttgcaaag ggtcaactca ttttttatgc tcctccagaa      900

tgggaacaga aaatccaaaa tacacacctc tctatctatg acaacttgct ctgggaatgt      960

aaagctagtg gaaagccaaa cccttggtat acatggttaa aaaatggtga acgactcaac     1020

ccagaggaga gaattcaaat agaaaatggg acactcatca taacgatgct gaatgtgtca     1080

gattctggtg tgtaccaatg tgctgcagaa aacaaatatc agataattta tgcaaatgct     1140

gaattgagag ttttagcctc agctccagat ttctccaaaa gtccagttaa aaaaaagtct     1200

tttgttcaag ttggtgggga tattgttatc ggatgcaaac caaatgcttt tcccagggca     1260

gctatctctt ggaaaagagg aacggagacc cttagacaaa gcaaaagaat atttctcttg     1320

gaggatggca gcctcaagat atataatatt accaggtcag atgctggatc atatacatgc     1380

atagccacaa atcagtttgg cactgcaaag aacactggca gcctcattgt aaaagagaga     1440

actgtcatta ccgtcccacc ttccaaaatg gatgttacag ttggcgagag tatagtgcta     1500

ccatgccagg tgtcccatga cccctccatt gaagtggtat ttgtatggtt tttcaatgga     1560

gatgtcatag acttaaaaaa aggagtggct cattttgaaa ggattggagg agaatctgtt     1620

ggggatttga tgataaggaa tattcagtta catcattcag gaaaatatct ctgcacagta     1680

caaacaaccc tagaaagttt atctgcagta gccgatatca ttgttagagg tccaccaggt     1740

cctcctgagg atgtgcaagt ggaagacatt tccagtacta cttctcaact aagttggaga     1800

gcaggcccag ataataacag tcccattcaa atatttacta ttcagactcg gacaccattt     1860

tctgtgggtt ggcaggctgt tgctacagtt ccagaaattc tcaatggtaa gacatacaat     1920

gcaacagtgg ttggtttgag tccttgggtg gaatatgaat ttcgtgttgt tgccggcaac     1980

agcattggga ttggagaacc aagtgaacca tcagaattgt taagaactaa agcatcagtc     2040

cctgttgtgg caccagtaaa catccatgga ggtggaggaa gtcggtctga actcgtcatt     2100

acatgggagt caattccaga agaactgcag aatggggagg gatttggata tatcatcatg     2160

ttccggccag tgggctcgac aacctggtcc aaggagaaag tgtcatctgt ggaatcatca     2220

aggtttgtct acagaaatga aagcatcatc ccactgtctc cctttgaagt caaagtgggt     2280

gtgtataata atgaaggaga aggatccctg agtactgtga ccattgtcta ctctggggaa     2340

gatgaacctc aactggcccc aaggggaact tctctccaga gtttttctgc ttctgaaatg     2400

gaggtttcat ggaatgctat tgcctggaat agaaacactg gaagagtgct gggctatgag     2460

gtcttatact ggacagatga ctccaaagaa tccatgatag gtaaaattag agtcagtgga     2520

aatgtcacaa ccaaaaacat cacggggctg aaagctaata ccatctactt tgcttccgta     2580

agagcttaca acactgctgg gacagggccc tcaagccccc cagtcaatgt taccaccaaa     2640

aagtctcctc caagccaacc accagcaaac attgcctgga agctgacaaa ctctaaatta     2700

tgcttgaact gggagcatgt aaaaaccatg gaaaatgagt ctgaagtttt ggggtacaag     2760

attctgtacc ggcaaaacag acagagtaaa actcatattt tggaaacaaa caatacatca     2820

gctgagcttc tggttccatt tgaagaagac tacttaattg aaataagaac agtcagtgat     2880

ggtggagatg gaagcagcag tgaggaaatt aggattccaa aaatgtcaag tttgagttcc     2940


<210>  3393
<211>  1674
<212>  DNA
<213>  Homo Sapiens

<400>  3393
tggggctact acggctgcga cgaggagctg gtgggtcccc tgtatgcacg ctccctgggc       60

gcctcctcct actacagtct ccttactgcg ccgagattcg ccaggctgca cggcataagc      120

gggtggtcac cacggattgg ggatccgaat ccctggctcc agatagactt aatgaagaag      180

caccggatcc gggccgtggc cacacagggc tcctttaatt cttgggactg ggtcacacgt      240

tacatgctac tctacggcga ccgagtggac agctggacac cgttctacca gcgagggcac      300

aactcgacct tctttggtaa cgtgaacgag tcggcggtgg tgcgccatga cctgcacttc      360

cacttcactg cgcgctacat ccgcatcgtg cccctggcct ggaacccacg cggcaagatc      420

ggcctgaggc tcggcctcta tggctgccca tacaaggccg acatactcta tttcgacggc      480

gacgatgcca tctcctaccg cttcccgcga ggggtcagcc gaagcctgtg ggacgtgttc      540

gccttcagct tcaagaccga ggagaaggac ggtcttctgc tgcacgccga gggcgcccag      600

ggcgactacg tgacgctcga gctggagggg gcacacctgc tgctgcacat gagcctgggc      660

agcagcccta tccagccaag accaggtcac accaccgtga gcgcaggcgg agtcctcaat      720

gaccagcact ggcactatgt gcgggtggac cgatttggcc gcgatgtaaa tttcaccctg      780

gacggctatg tgcagcgctt tattctcaat ggagacttcg agaggctgaa cctggacact      840

gagatgttca tcggaggtct ggtgggcgcc gcgcggaaga acctggccta tcggcataac      900

ttccgcggct gcatagaaaa cgtaatcttc aaccgcgtca acatcgcaga cctggccgtg      960

cggcgccatt cccggatcac cttcgagggt aaggtggctt ttcgttgcct ggacccggta     1020

ccgcacccta tcaacttcgg aggccctcac aacttcgttc aagtgcccgg tttcccacgc     1080

cgtggccgcc tggcagtctc atttcgcttc cgcacctggg acctcaccgg gcttctcctt     1140

ttctcccgtc tgggggacgg gctgggccac gtggagctga cgctcagcga agggcaggtc     1200

aacgtgtcca tcgcgcagag cggccgaaag aagcttcagt tcgctgctgg gtaccgactg     1260

aatgacggct tttggcacga ggtgaatttt gtggcacagg aaaaccatgc agttatcagc     1320

attgatgatg tggaaggggc agaggtcagg gtctcatacc cgttgctgat ccggacaggg     1380

acctcatatt tctttggggg ttgtcccaag ccagccagtc gatgggactg ccactccaac     1440

cagacggcat tccatggctg catggagctg ctcaaggtgg atggtcaact ggtcaacctg     1500

actctggtgg agggccggcg gcttggattc tatgctgagg tcctctttga tacatgtggc     1560

atcactgata ggtgcagccc taacatgtgt gagcatgatg gacgctgcta ccagtcttgg     1620

gatgacttca tttgctactg cgaactgacg ggctacaagg gagagacctg ccac           1674


<210>  3394
<211>  3705
<212>  DNA
<213>  Homo Sapiens

<400>  3394
gctccctcca cgtcccaaaa atgtgatgag ccacttgtct ctggactccc ccatgtggct       60

ttcagcagct cctcctccat ctctggtagc tattctcccg gctatgccaa gataaacaag      120

agaggaggtg ctgggggatg gtctccatca gacagcgacc attatcaatg gcttcaggtt      180

gactttggca atcggaagca gatcagtgcc attgcaaccc aaggaaggta tagcagctca      240

gattgggtga cccaataccg gatgctctac agcgacacag ggagaaactg gaaaccctat      300

catcaagatg ggaatatctg ggcatttccc ggaaacatta actctgacgg tgtggtccgg      360

cacgaattac agcatccgat tattgcccgc tatgtgcgca tagtgcctct ggattggaat      420

ggagaaggtc gcattggact cagaattgaa gtttatggct gttcttactg ggctgatgtt      480

atcaactttg atggccatgt tgtattacca tatagattca gaaacaagaa gatgaaaaca      540

ctgaaagatg tcattgcctt gaactttaag acgtctgaaa gtgaaggagt aatcctgcac      600

ggagaaggac agcaaggaga ttacattacc ttggaactga aaaaagccaa gctggtcctc      660

agtttaaact taggaagcaa ccagcttggc cccatatatg gccacacatc agtgatgaca      720

ggaagtttgc tggatgacca ccactggcac tctgtggtca ttgagcgcca ggggcggagc      780

attaacctca ctctggacag gagcatgcag cacttccgta ccaatggaga gtttgactac      840

ctggacttgg actatgagat aacctttgga ggcatccctt tctctggcaa gcccagctcc      900

agcagtagaa agaatttcaa aggctgcatg gaaagcatca actacaatgg cgtcaacatt      960

actgatcttg ccagaaggaa gaaattagag ccctcaaatg tgggaaattt gagcttttct     1020

tgtgtggaac cctatacggt gcctgtcttt ttcaacgcta caagttacct ggaggtgccc     1080

ggacggctta accaggacct gttctcagtc agtttccagt ttaggacatg gaaccccaat     1140

ggtctcctgg tcttcagtca ctttgcggat aatttgggca atgtggagat tgacctcact     1200

gaaagcaaag tgggtgttca catcaacatc acacagacca agatgagcca aatcgatatt     1260

tcctcaggtt ctgggttgaa tgatggacag tggcacgagg ttcgcttcct agccaaggaa     1320

aattttgcta ttctcaccat cgatggagat gaagcatcag cagttcgaac taatagtccc     1380

cttcaagtta aaactggcga gaagtacttt tttggaggtt ttctgaacca gatgaataac     1440

tcaagtcact ctgtccttca gccttcattc caaggatgca tgcagctcat tcaagtggac     1500

gatcaacttg taaatttata cgaagtggca caaaggaagc cgggaagttt cgcgaatgtc     1560

agcattgaca tgtgtgcaat catagacaga tgtgtgccca atcactgtga gcatggtgga     1620

aagtgctcgc aaacatggga cagcttcaaa tgcacttgtg atgagacagg atacagtggg     1680

gccacctgcc acaactctat ctacgagcct tcctgtgaag cctacaaaca cctaggacag     1740

acatcaaatt attactggat agatcctgat ggcagcggac ctctggggcc tctgaaagtt     1800

tactgcaaca tgacagagga caaagtgtgg accatagtgt ctcatgactt gcagatgcag     1860

acgcctgtgg tcggctacaa cccagaaaaa tactcagtga cacagctcgt ttacagcgcc     1920

tccatggacc agataagtgc catcactgac agtgccgagt actgcgagca gtatgtctcc     1980

tatttctgca agatgtcaag attgttgaac accccagatg gaagccctta cacttggtgg     2040

gttggcaaag ccaacgagaa gcactactac tggggaggct ctgggcctgg aatccagaaa     2100

tgtgcctgcg gcatcgaacg caactgcaca gatcccaagt actactgtaa ctgcgacgcg     2160

gactacaagc aatggaggaa ggatgctggt ttcttatcat acaaagatca cctgccagtg     2220

agccaagtgg tggttggaga tactgaccgt caaggctcag aagccaaatt gagcgtaggt     2280

cctctgcgct gccaaggaga caggaattat tggaatgccg cctctttccc aaacccatcc     2340

tcctacctgc acttctctac tttccaaggg gaaactagcg ctgacatttc tttctacttc     2400

aaaacattaa ccccctgggg agtgtttctt gaaaatatgg gaaaggaaga tttcatcaag     2460

ctggagctga agtctgccac agaagtgtcc ttttcatttg atgtgggaaa tgggccagta     2520

gagattgtag tgaggtcacc aacccctctc aacgatgacc agtggcaccg ggtcactgca     2580

gagaggaatg tcaagcaggc cagcctacag gtggaccggc taccgcagca gatccgcaag     2640

gccccaacag aaggccacac ccgcctggag ctctacagcc agttatttgt gggtggtgct     2700

gggggccagc agggcttcct gggttgcatc cgctccttga ggatgaatgg ggtgacactt     2760

gacctggagg aaagagcaaa ggtcacatct gggttcatat ccggatgctc gggccattgc     2820

accagctatg gaacaaactg tgaaaatgga ggcaaatgcc tagagagata ccacggttac     2880

tcctgcgatt gctctaatac tgcatatgat ggaacatttt gcaacaaaga tgttggtgca     2940

ttttttgaag aagggatgtg gctacgatat aactttcagg caccagcaac aaatgccaga     3000

gactccagca gcagagtaga caacgctccc gaccagcaga actcccaccc ggacctggca     3060

caggaggaga tccgcttcag cttcagcacc accaaggcgc cctgcattct cctctacatc     3120

agctccttca ccacagactt cttggcagtc ctcgtcaaac ccactggaag cttacagatt     3180

cgatacaacc tgggtggcac ccgagagcca tacaatattg acgtagacca caggaacatg     3240

gccaatggac agccccacag tgtcaacatc acccgccacg agaagaccat ctttctcaag     3300

ctcgatcatt atccttctgt gagttaccat ctgccaagtt catccgacac cctcttcaat     3360

tctcccaagt cgctctttct gggaaaagtt atagaaacag ggaaaattga ccaagagatt     3420

cacaaataca acaccccagg attcactggt tgcctctcca gagtccagtt caaccagatc     3480

gcccctctca aggccgcctt gaggcagaca aacgcctcgg ctcacgtcca catccagggc     3540

gagctggtgg agtccaactg cggggcctcg ccgctgaccc tctcccccat gtcgtccgcc     3600

accgacccct ggcacctgga tcacctggat tcagccagtg cggattttcc atataatcca     3660

ggacaaggcc aagctataag aaatggagtc aacagaaact cggct                     3705


<210>  3395
<211>  2631
<212>  DNA
<213>  Homo Sapiens

<400>  3395
ggaaatccac ctgactgtga tgccccactg gcctctgcct tgcctaggtc atccttcagc       60

agctcctcag agctgtccag cagccacggc ccggggtttt caaggcttaa tcgaagagat      120

ggagctggtg gctggactcc acttgtgtca aataaatacc aatggctgca aattgacctt      180

ggagagagaa tggaggtcac tgctgtcgcc acccaaggag gatatgggag ctctgactgg      240

gtgaccagct acctcctgat gttcagtgat ggtgggagaa actggaagca gtatcgccga      300

gaagaaagca tctggggttt tccaggaaac acaaacgcag acagtgtggt gcactacaga      360

ctccagcctc cctttgaagc caggttcctg cgctttctcc ctttagcctg gaaccctagg      420

ggcaggattg ggatgcggat cgaagtgtac ggatgtgcat ataaatctga ggtggtttat      480

tttgatggac aaagtgctct gctgtataga cttgataaaa aacctttaaa accaataaga      540

gacgttattt ctttgaaatt taaagccatg cagagcaatg gaattctact tcacagagaa      600

ggacaacatg gaaatcacat tactctggaa ttaattaaag gaaagcttgt cttttttctt      660

aattcaggca atgctaagct gccttccact attgctcctg tgaccctcac cctgggcagc      720

ctgctggacg accagcactg gcattccgtc ctcatcgagc tcctcgacac gcaggtcaac      780

ttcaccgtgg acaaacacac tcatcatttc caagcaaagg gagattccag ttacttggat      840

cttaattttg agatcagctt tgggggaatt ccgacacccg gaagatcgcg ggcattcaga      900

cgtaaaagct ttcatgggtg tttagaaaat ctttattata atggagtgga tgttaccgaa      960

ttagccaaga aacacaaacc acagatcctc atgatgggaa atgtgtcctt ctcatgtcca     1020

cagccacaga ctgtccctgt gacttttctg agctccagga gttatctggc tctgccaggc     1080

aactctgggg aggacaaagt gtctgtcact tttcaatttc gaacgtggaa cagagcagga     1140

catttgcttt tcggcgaact tcgacgtggt tcagggagtt tcgtcctctt tcttaaggat     1200

ggcaagctca aactgagtct cttccagccg ggacagtcac caaggaatgt cacagcaggt     1260

gctggattaa acgatgggca gtggcactct gtgtccttct ctgccaagtg gagccatatg     1320

aatgtggtgg tggacgatga cacagctgtt cagcccctgg tggctgtgct cattgattca     1380

ggtgacacct attattttgg agctctctac gagcagtctt gtgaagccca caagcaccga     1440

gggaacccgt ctgggcttta ctatattgat gcagatggaa gtggccccct gggaccattt     1500

cttgtgtact gcaatatgac agacgccgcg tggacggtgg tgcagcacgg tggccccgac     1560

gcggtgaccc tccgaggtgc ccccagcggg cacccgcgct cggctgtgtc cttcgcgtac     1620

gcagcgggcg cggggcagct gcggtccgcg gtgaacctgg cggagcgctg cgagcagcgg     1680

ctggctctgc gctgcgggac ggcgcggcgc ccggactcac gagatggaac cccactgagc     1740

tggtgggttg gaagaaccaa tgaaacacac acctactggg gagtttctct gcctgatgct     1800

caaaagtgta cttgtggatt agaggggaac tgcattgatt ctcagtatta ctgcaactgt     1860

gatgctggcc ggaatgaatg gactagtgac acaatagtcc tttcccaaaa ggagcacctg     1920

ccagtcactc agattgtgat gacagacgca ggccgaccac attccgaagc agcttataca     1980

ctggggccac tgctctgccg cggagatcag tcattctgga attcagcttc cttcaacact     2040

gagacttcat accttcattt ccctgctttc cacggagaac tcactgctga cgtgtgcttc     2100

ttttttaaga ccacagtttc ctccggggtg tttatggaga acctggggat cacagatttc     2160

atcaggattg agctgcgtgc tcccacagaa gtgacctttt ccttcgatgt ggggaatgga     2220

ccttgtgagg tcacggtgca gtcacccact ccctttaatg acaatcagtg gcaccacgtg     2280

agggcagaga gaaatgttaa aggagcgtct cttcaagttg atcagcttcc tcagaagatg     2340

cagcctgccc ctgctgatgg gcacgttcgt ttacagctca acagccagct cttcattggt     2400

ggaacggcca ccagacagag aggctttcta ggatgcattc ggtctctgca gttgaacggg     2460

gtggccctgg atctggaaga aagagccaca gtgacgccag gagtggagcc agggtgtgca     2520

ggacactgca gcacctatgg acacttgtgt cgcaatggag ggagatgcag agagaaacgc     2580

aggggggtca cctgtgactg tgccttctca gcctatgatg ggccgttctg c              2631


<210>  3396
<211>  3648
<212>  DNA
<213>  Homo Sapiens

<400>  3396
gggaattcct atgactgtga tgatcctctt gtgtctgcct tgcctcaggc atccttcagc       60

agttcttccg agctctccag cagtcatggt cctggatttg caaggctgaa tagaagagat      120

ggagctggtg gctggtctcc acttgtgtct aacaaatacc agtggttgca gattgacctt      180

ggagagagaa tggaggtcac cgctgtggcc actcaagggg gatatggtag ctccaactgg      240

gtgaccagct acctcctgat gttcagtgat agtggctgga actggaaaca atatcgccaa      300

gaggacagca tctggggttt ttcaggaaat gcaaatgcag acagtgttgt gtactataga      360

ctccagcctt ctatcaaagc cagatttctg cgcttcatcc ctttggaatg gaaccccaag      420

ggcagaattg gaatgcgaat cgaagtgttc ggatgtgcat acagatcaga agtggttgat      480

cttgatggaa aaagttccct tctctacaga tttgatcaaa aatccctgag cccaataaaa      540

gacattattt ctttgaaatt caaaaccatg cagagtgatg ggattctact ccacagggaa      600

gggccaaatg gagatcacat cacactgcaa ttaagaagag caagactctt tttacttatt      660

aattcaggtg aagctaaact gccttccact tccaccctgg tcaatctcac cctgggcagc      720

ctgctagatg atcagcattg gcattcagtg ctcatccagc gtttgggcaa acaagtcaac      780

ttcacagtgg acgaacacag gcatcatttc catgcacggg gagaattcaa tctcatgaat      840

cttgattatg agatcagctt tggagggatt ccagcacctg gaaaatcagt gtcattccca      900

catagaaatt ttcatggatg tttagaaaat ctctattata atggagtgga tatcattgat      960

ttggccaagc agcaaaaacc acagatcatt gctatgggaa atgtgtcatt ttcttgttca     1020

caaccacaat ctatgcccgt gacttttctg agctccagga gttatttagc actgccagac     1080

ttctctggag aggaggaggt ttctgccact tttcaatttc gaacttggaa taaggcaggg     1140

cttctgctgt tcagtgaact tcagctgatt tcagggggta tcctcctctt tctgagtgat     1200

ggaaaactta agtcgaatct ctaccagcca ggaaaattac ccagtgacat cacagcaggt     1260

gtcgaattaa atgatgggca gtggcattct gtctctttat ctgctaaaaa gaatcacttg     1320

agtgtggcgg tggacggcca gatggcttct gctgctcctc tgctggggcc tgagcagatt     1380

tattcgggtg gcacctatta ttttggaggt tgtcctgaca aaagctttgg atccaaatgt     1440

aaaagtccac ttggtggatt tcagggatgt atgaggctca tttctatcag cggcaaagtg     1500

gtagatctga tttcagttca gcaggggtcc cttgggaact tcagtgacct tcagatagac     1560

tcatgtggca tctcagacag gtgtttgccc aactattgtg aacacggtgg ggagtgttcc     1620

cagtcctgga gcacctttca ttgtaactgt accaacactg gttacagagg agctacttgc     1680

cataactcta tctatgagca gtcatgtgaa gcctataagc acagaggaaa tacttcaggg     1740

ttttactata tagattcaga tggaagtggt cccctggaac catttcttct atattgcaat     1800

atgaccgaaa ctgcatggac catcatacag cacaacggct ctgacttaac aagagtcaga     1860

aatactaatc cagagaaccc atatgctggg tttttcgagt atgtggccag catggagcaa     1920

cttcaggcca ctattaaccg tgcagagcac tgtgaacagg agtttactta ttactgcaag     1980

aagtcacggc tggtcaataa gcaagatgga acccctctga gttggtgggt aggaagaacc     2040

aatgaaacgc aaacctactg gggaggttct tcgcctgatc ttcaaaaatg tacttgtgga     2100

ttagagggaa actgcattga ttctcagtat tactgcaatt gtgatgctga ccggaatgaa     2160

tggaccaatg acactggatt gcttgcttat aaagaacatc ttccagtaac taagatcgtg     2220

attacagaca caggccgact gcattcagaa gcagcttata aactggggcc tctgctctgc     2280

cagggagaca gatcattttg gaattcagct tcctttgata ccgaggcttc atatcttcat     2340

tttcctacct tccacggaga acttagcgcg gatgtatctt tcttttttaa gacaacagct     2400

tcatctgggg tatttttaga gaacttgggg attgctgatt ttatacggat agagcttcgc     2460

tctccgacag tagtgacttt ttcatttgat gtggggaatg ggccttttga aatctcagtg     2520

cagtcaccca cccacttcaa cgacaaccag tggcaccatg tgagggttga aaggaacatg     2580

aaggaggcct cccttcaagt ggatcagctg acaccaaaga cacagcccgc ccccgctgat     2640

gggcatgtcc tgttacagct caacagtcag ctcttcgtgg gtggaacggc caccagacag     2700

agaggctttc tgggctgcat tcggtctctg cagttgaatg ggatgaccct ggatttggaa     2760

gaaagagccc aggtgactcc agaagtgcag ccaggttgta ggggacattg cagcagctat     2820

gggaagttat gccgcaatgg agggaaatgc agagaaagac ccattgggtt cttttgtgac     2880

tgcactttct ctgcatacac agggccattc tgctcaaatg agatttctgc atattttgga     2940

tctggctcat ccgtgatata caattttcaa gaaaattatc ttttaagtaa aaactccagc     3000

tcccacgctg cttcatttca tggtgatatg aagctgagca gagaaatgat caaatttagt     3060

ttccgaacaa cacgaacacc aagcttgctg ctttttgtga gctcctttta caaagaatac     3120

ctttctgtga tcattgccaa aaatggaagt ttgcagatca ggtacaagtt aaataaatat     3180

caagagcctg atgttgttaa ctttgatttt aaaaacatgg ctgatggaca acttcaccac     3240

ataatgatta acagagaaga aggagtggtc tttatagaga ttgacgataa tagaaggaga     3300

caagttcacc tgtcatcagg cacagaattc agtgcagtca aatctctggt attgggcagg     3360

attttagaac acagtgatgt ggaccaggat actgcactgg caggtgcgca gggcttcaca     3420

ggctgcctct ctgcagtgca gctcagccac gtggcccctc tgaaggcagc tctgcacccc     3480

agccacccag accctgtcac tgttacagga cacgtgactg agtccagctg tatggcccag     3540

cctggcactg atgccacatc aagggaaagg acacactcgt ttgcagatca ttctggaaca     3600

atagatgaca gagagcccct tgctaatgca atcaaaagtg actctgca                  3648


<210>  3397
<211>  3639
<212>  DNA
<213>  Homo Sapiens

<400>  3397
gcgacaaact acaactgtga tgatccacta gcatccctgc tctctccaat ggctttttcc       60

agttcctcag acctcactgg cactcacagc ccagctcaac tcaactggag agttggaact      120

ggcggttggt ccccagcaga ttccaatgct caacagtggc tccagatgga cctgggaaac      180

agagtagaga ttacagcagt ggccacgcag ggaagatacg gaagctctga ctgggtgacg      240

agttacagcc tgatgttcag tgacacagga cgcaactgga aacagtacaa acaagaagac      300

agcatctgga cctttgcagg aaacatgaat gctgacagcg tggtgcacca caagctattg      360

cactcagtga gagcccgatt tgttcgcttt gtgcccctgg aatggaatcc cagtgggaag      420

attggcatga gagtcgaggt ctacggatgt tcctataaat cagatgttgc tgactttgat      480

ggccgaagct cacttctgta caggttcaat cagaagttga tgagtactct caaagatgtg      540

atctccctga agttcaagag catgcaagga gatggggtcc tgttccatgg agaaggtcag      600

cgtggagacc acatcacctt ggaactccag aaggggaggc tcgccctaca cctcaatttg      660

ggtgacagca aagcgcggct cagcagcagc ttgccctctg ccaccctggg cagcctcctg      720

gatgaccagc actggcactc ggtcctcatt gagcgggtgg gcaagcaggt gaacttcacg      780

gtggacaagc acacacagca cttccgcacc aagggcgaga cggatgcctt agacattgac      840

tatgagctta gttttggagg aattccagta ccaggaaaac ctgggacctt tttaaagaaa      900

aacttccatg gatgcatcga aaacctttac tacaatggag taaacataat tgacctggct      960

aagagacgaa agcatcagat ctatactggc aatgtcactt tttcctgctc cgaaccacag     1020

attgtgccca tcacatttgt caactccagc ggcagctatt tgctgctgcc cggcaccccc     1080

caaattgatg ggctctcagt gagtttccag tttcgaacat ggaacaagga tggtctgctt     1140

ctgtccacag agctgtctga gggctcggga accctgctgc tgagcctgga gggtggaatc     1200

ctgagactcg tgattcagaa aatgacagaa cgcgtagctg aaatcctcac aggcagcaac     1260

ttgaatgatg gcctgtggca ctcggttagc atcaacgcca ggaggaaccg catcacgctc     1320

actctggatg atgaagcagc acccccggct ccagacagca cttgggtgca gatttattct     1380

ggaaatagct actattttgg agggtgcccc gacaatctca ccgattccca atgtttaaat     1440

cccattaagg ctttccaagg ctgcatgagg ctcatcttta ttgataacca gcccaaggac     1500

ctcatttcag ttcagcaagg ttccctgggg aattttagtg atttacacat tgatctgtgt     1560

agcatcaaag acaggtgttt gccaaactac tgtgaacatg gaggaagctg ctcccagtcc     1620

tggactacct tctattgtaa ctgcagtgac acaagttaca ctggtgccac ctgccacaac     1680

tccatctacg agcaatcctg cgaggtgtac aggcaccagg ggaatacagc cggcttcttc     1740

tacatcgact cagatggcag cggcccactg ggacctctcc aggtgtactg caatatcact     1800

gaggacaaga tctggacatc agtgcagcac aacaatacag agctgacccg agtgcggggc     1860

gctaaccctg agaagcccta tgccatggcc ttggactacg ggggcagcat ggaacagctg     1920

gaggccgtga tcgacggctc tgagcactgt gagcaggagg tggcctacca ctgcaggagg     1980

tcccgcctgc tcaacacgcc ggatggaaca ccatttacct ggtggattgg gcggtccaat     2040

gaaaggcacc cttactgggg aggttcccct cctggggtcc agcagtgtga gtgtggccta     2100

gacgagagct gcctggacat tcagcacttt tgcaattgcg acgctgacaa ggatgaatgg     2160

acaaatgata ctggctttct ttccttcaaa gaccacttgc ctgtcactca gatagttatc     2220

actgataccg acagatcaaa ctcagaagcc gcttggagaa ttggtccctt gcgttgctat     2280

ggtgaccgac gcttctggaa cgccgtctca ttttatacag aagcctctta cctccacttt     2340

cctaccttcc atgcggaatt cagtgccgat atttccttct tttttaaaac cacagcatta     2400

tccggagttt tcctagaaaa tcttggcatt aaagacttca ttcgactcga aataagctct     2460

ccttcagaga tcacctttgc catcgatgtt gggaatggtc ctgtggagct tgtagtccag     2520

tctccttctc ttctgaatga caaccaatgg cactatgtcc gggctgagag gaacctcaag     2580

gagacctccc tgcaggtgga caaccttcca aggagcacca gggagacgtc ggaggagggc     2640

cattttcgac tgcagctgaa cagccagttg tttgtagggg gaacgtcatc cagacagaaa     2700

ggcttcctag gatgcattcg ctccttacac ttgaatggac agaaaatgga cctggaagag     2760

agggcaaagg tcacatctgg agtcaggcca ggctgccccg gccactgcag cagctacggc     2820

agcatctgcc acaacggggg caagtgtgtg gagaagcaca atggctacct gtgtgattgc     2880

accaattcac cttatgaagg gcccttttgc aaaaaagagg tttctgctgt ttttgaggct     2940

ggcacgtcgg ttacttacat gtttcaagaa ccctatcctg tgaccaagaa tataagcctc     3000

tcatcctcag ctatttacac agattcagct ccatccaagg aaaacattgc acttagcttt     3060

gtgacaaccc aggcacccag tcttttgctc tttatcaatt cttcttctca ggacttcgtg     3120

gttgttctgc tctgcaagaa tggaagctta caggttcgct atcacctaaa caaggaagaa     3180

acccatgtat tcaccattga tgcagataac tttgctaaca gaaggatgca ccacttgaag     3240

attaaccgag agggaagaga gcttaccatt cagatggacc agcaacttcg actcagttat     3300

aacttctctc cggaagtaga gttcagggtt ataaggtcac tcaccttggg caaagtcaca     3360

gagaatcttg gtttggattc tgaagttgct aaagcaaatg ccatgggttt tgctggatgc     3420

atgtcttccg tccagtacaa ccacatagca ccactgaagg ctgccctgcg ccatgccact     3480

gtcgcgcctg tgactgtcca tgggaccttg acggaatcca gctgtggctt catggtggac     3540

tcagatgtga atgcagtgac cacggtgcat tcttcatcag atccttttgg gaagacagat     3600

gagcgggaac cactcacaaa tgctgttcga agtgattcg                            3639


<210>  3398
<211>  2277
<212>  DNA
<213>  Homo Sapiens

<400>  3398
atggatcctg gagcattgga gatgaaaaat ttcaataaga tcatcagctt tctatacagc       60

actgttggag ccctgaacaa gattggcaca gatggaaccc aagttgcaat ggttcagttc      120

actgatgatc ccagaacaga atttaaacta aatgcttaca aaaccaaaga gactcttctt      180

gatgcaatta aacacatttc atacaaagga ggaaatacaa aaacaggaaa agcaattaag      240

tatgttcgag ataccttgtt cactgcagag tcaggtacaa gaaggggcat cccaaaggtt      300

atcgtggtta taactgatgg aagatcacaa gatgatgtga acaaaatctc cagggagatg      360

caattagatg gctatagcat ttttgcaatt ggtgtggccg atgcagatta ctcggagttg      420

gttagcattg gcagtaagcc cagcgcacgc catgtcttct ttgtggatga ctttgacgcc      480

tttaagaaaa tcgaagatga gttaattact tttgtctgcg aaacagcatc agcaacctgt      540

ccagtggtac acaaggatgg cattgatctt gcaggattta agatgatgga aatgtttggt      600

ttggttgaaa aagatttttc atcagtggaa ggggtttcta tggagcctgg taccttcaat      660

gtgtttccat gttaccaact ccataaagat gccctggttt cccagccaac caggtacttg      720

cacccagaag gattgccctc cgactacaca atcagttttc tattccggat tcttcctgac      780

actccacagg agccatttgc tctttgggag attttaaata aaaattctga cccattggtt      840

ggggttattt tagacaatgg tgggaaaact ctaacatatt tcaactatga ccagagtggg      900

gattttcaaa ctcttacttt cgaaggacct gaaattagga aaatttttta tggaagcttt      960

cacaagctac acattgttgt cagtgagact ttggtcaaag tggttattga ctgcaagcaa     1020

gtgggtgaga aggcaatgaa cgcatcagct aatatcacgt cagatggtgt agaagtgcta     1080

gggaaaatgg ttcgatcaag aggaccaggt ggaaactctg caccgttcca gttacagatg     1140

tttgatattg tttgctccac atcatgggcc aatacagaca aatgctgtga acttccaggc     1200

ctgagagatg atgagtcttg cccagacctt ccccattcct gctcctgttc tgaaaccaat     1260

gaagtggctc tgggaccagc gggcccacca ggtggtccag gactccgagg accaaagggc     1320

cagcaaggtg aaccgggtcc aaagggacca gatggccctc ggggtgaaat tggtctgcca     1380

ggacctcagg gtccacctgg acctcaagga ccaagtggtc tgtccattca aggaatgccc     1440

ggaatgccag gagaaaaagg agagaaagga gatactggcc ttccaggtcc acagggtatc     1500

ccaggaggcg ttggttcacc aggacgtgat ggctcaccag gccagagggg ccttccggga     1560

aaggatggat cctcgggacc tccaggacca ccagggccaa taggcattcc tggcacccct     1620

ggagtcccag ggatcacagg aagcatggga ccgcaaggcg ccctgggacc acctggtgtc     1680

cctggagcaa agggggaacg aggagagcgg ggtgacctgc agtctcaagc catggtgaga     1740

tcagtggcgc gtcaagtatg cgaacagctc atccagagtc acatggccag gtacactgcc     1800

atcctcaacc agattcccag ccactcctca tccatccgga ctgtccaagg gcctcctggg     1860

gagcctggga ggccaggctc acctggagcc cctggtgaac aaggaccccc aggcacacca     1920

ggcttccccg gaaatgcagg cgtgccaggg accccaggag aacgaggtct aactggtatc     1980

aaaggagaaa aaggaaatcc aggcgttgga acccaaggtc caagaggccc ccctggacca     2040

gcaggacctt caggggagag tcggcctggc agccctgggc cccctggctc tcctggacca     2100

agaggcccac caggtcatct gggggttcct ggaccccaag gtccttctgg ccagcctgga     2160

tattgtgacc cctcatcatg ttctgcctat ggtgtgagag ctccccatcc agatcagcca     2220

gagttcaccc ctgtccaaga tgagctggaa gccatggaac tgtggggccc tggagtc        2277


<210>  3399
<211>  3786
<212>  DNA
<213>  Homo Sapiens

<400>  3399
agagagcaag ttcaagcaag cggtctcctg aggctggctg tgctgcctga ggaccggctg       60

cagatgaagt ggagagagtc ggaggggagc ggcctcggct acctggtgca ggtgaagccc      120

atggcagggg actcggaaca ggaggtgata ctgaccacca agacccataa ggccacagtg      180

gggggcctga gcccctccaa gggctacacc ttgcagatct tcgagctcac tggctctggg      240

cgcttcctgc tagctcggag ggagtttgtg attgaggatc tgaagagtag ctccctggac      300

aggagcagcc agaggcccct cggctctgga gccccggagc ccaccccctc ccacacgggg      360

agcccagacc ctgagcaggc ttctgagccc caagttgcct tcacaccaag ccaggatccg      420

cgcactcctg ccggccccca gttccgctgc ctgccccccg tgcctgctga catggtcttc      480

ctggtggacg ggtcctggag cattggccac agtcacttcc agcaggtcaa ggacttcctg      540

gccagtgtca tcgcaccctt tgaaatcggg ccggataagg tccaagtagg cctgactcag      600

tacagcgggg atgctcagac tgagtgggac ctgaactccc tcagcaccaa ggaacaggtg      660

ctggcagctg tgcgccgcct ccgctacaag ggggggaaca cgttcacagg ccttgccctg      720

acccacgtgc tggggcagaa cctgcagccg gcggctggcc tccgtccaga ggcagccaag      780

gtggtgattc tggtgacgga cggcaagtcc caggacgatg tgcacactgc tgcccgtgtc      840

ctcaaggacc tgggcgtgaa cgtcttcgct gtgggtgtga agaacgccga tgaggctgag      900

ctgaggctcc tggcgtcccc gccgagggac atcaccgtcc acagcgtgct ggacttcctg      960

cagctcggcg cgctggctgg cctgctcagc cgtctcatct gccagaggct ccagggtggg     1020

agcccgcggc agggcccagc agcggctcca gccctggaca ccctccctgc ccccaccagc     1080

ctggtcctga gccaggtgac ctcctccagc atccgcctgt cctggactcc agccccccgg     1140

caccccctca agtatctgat cgtttggcga gcctctagag gtggcacccc cagggaggtg     1200

gtggtggagg ggcccgccgc ctccacggag ctgcacaacc tggcctcccg cacagagtac     1260

ctggtctccg tgttccccat ctatgagggc ggggttggcg aaggcctgcg gggcctggtg     1320

accacagcac ctctgcctcc gccccgggcg ctgaccctgg ccgcagtgac gcccagaacc     1380

gtccacctca cctggcagcc atcggccggg gccacccact acctggtgcg atgttctcct     1440

gcttccccca agggtgaaga ggaggagcga gaggtgcagg tcgggcggcc cgaggtgctg     1500

ctggatggcc tggaacctgg cagggactat gaggtctcgg tgcagagcct gcgaggccct     1560

gagggcagcg aggcccgggg catccgtgcc aggaccccca ccctggcccc cccgagacac     1620

ctgggcttct cagacgtgag ccacgacgcg gcacgagtgt tctgggaggg tgccccgagg     1680

cctgtgcgcc tggtcagggt cacctatgtg tccagcgagg gtggacactc ggggcagaca     1740

gaggctcctg ggaacgccac ctcggccacg ctggggcctc tctcttcctc caccacctac     1800

actgtccgtg tcacctgcct ctaccctggg ggtggctcct ctacgctgac tggccgggtg     1860

accaccaaga aagctcccag cccaagccag ctgtccatga cggagctgcc aggggatgca     1920

gtccagctgg cgtgggtggc cgcagccccg tctggcgtgc ttgtctacca gatcacgtgg     1980

acgcccctgg gagaggggaa ggctcacgag atctctgtcc cagggaacct cggcacggcc     2040

gtcctgcctg gcctagggag gcacacagag tacgacgtca ccatcttggc ctactacagg     2100

gacggggccc gcagtgaccc tgtgtccctc cgctataccc cctccacggt gagcaggagc     2160

ccaccctcca acctggccct ggcctcggag acccccgaca gcctgcaggt cagctggacg     2220

cccccgcttg gccgcgtgct ccattactgg ctcacctacg cccccgcctc tggcttggga     2280

cccgagaaat ccgtctctgt gccaggagcc aggagccacg tgacactgcc cgacctgcag     2340

gcagccacga agtacagggt cctggtctca gctatctatg cagcaggcag gagtgaggct     2400

gtgtctgcca cgggccagac agcctgccca gccctccgcc ctgacggctc cctcccaggg     2460

tttgacctga tggtggcctt cagcctggtg gaaaaggctt atgcgtccat ccggggcgtg     2520

gccatggagc cctctgcctt cggtgggacc ccgaccttca cgctcttcaa ggacgcccag     2580

ctgacaagac gggtcagtga cgtctaccca gcccccctac ctccagagca caccatcgtc     2640

ttccttgtgc gcctacttcc cgagacaccc cgtgaggcct tcgcgctgtg gcagatgaca     2700

gccaaggact tccagcccct ccttggggtt ctgctggatg ccgggaagaa gtccctgacc     2760

tacttccacc gtgaccccag ggctgccttg caggaggcca ccttcgaccc gcaggaagtg     2820

aggaagattt tcttcgggag cttccacaag gtgcacgtgg ctgtgggccg ctccaaggtc     2880

aggctctatg tggactgccg gaaggtggct gagcggcccc ttggggagat gggcagccca     2940

cccgctgccg gcttcgtcac gctggggagg ctggccaagg ccaggggccc caggagcagt     3000

tcggccgcgt ttcagctcca gatgctgcag atcgtgtgca gtgacacctg ggccgatgag     3060

gaccggtgct gtgagctccc tgcctcgagg gatggagaga cctgccccgc cttcgtgtct     3120

gcctgttcct gttcctcaga gacccctggg cccccaggac ctcaaggacc cccaggcctc     3180

cctgggagga atggcacccc aggagagcag ggcttcccag ggcccagggg tccaccaggg     3240

gtcaaaggag agaagggaga ccatgggctt ccaggcttgc agggccaccc cggccaccag     3300

ggcatccccg ggagagttgg cctccaggga ccaaagggaa tgagaggcct ggagggaact     3360

gctggcctgc ctggaccccc tggccccagg gggttccagg gcatggcagg ggccaggggc     3420

actagtggag agcgaggacc tccagggacc gtggggccca caggactgcc agggcccaaa     3480

ggggaacgag gagagaaggg cgagcagcag tcccttgcca ccctctacca gcttgtgagc     3540

caggcctcac acgtgtcaaa gttcgactcc ttccacgaga acaccaggcc ccccatgccc     3600

atcttggagc agaagctgga gccgggcact gagcccctgg ggtcacctgg cacccgcagc     3660

aaggccctgg ttcctggaga atgggggcgt ggtggccgcc accttgaggg cagaggggag     3720

cctggagctg ttggtcagat gggcagccct gggcagcagg gggctagcac ccagggcctc     3780

tgggag                                                                3786


<210>  3400
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  3400
ctggatattg atagccgtcc taccgctgaa gtctgtgcca cacacacaat ttcaccagga       60

cccaaaggag atgatggtga aaaaggagat ccaggagaag agggaaagca tggcaaagtg      120

ggacgcatgg ggccgaaagg aattaaagga gaactgggtg atatgggaga tcagggcaat      180

attggcaaga ctgggcccat tgggaagaag ggtgacaaag gggaaaaagg tttgcttgga      240

atacctggag aaaaaggcaa agcaggtact gtctgtgatt gtggaagata ccggaaattt      300

gttggacaac tggatattag tattgctcgg ctcaagacat ctatgaagtt tgtcaagaat      360

gtgatagcag ggattaggga aactgaagag aaattctact acatcgtgca ggaagagaag      420

aactacaggg aatccctaac ccactgcagg attcggggtg gaatgctagc catgcccaag      480

gatgaagctg ccaacacact catcgctgac tatgttgcca agagtggctt ctttcgggtg      540

ttcattggcg tgaatgacct tgaaagggag ggacagtaca tgttcacaga caacactcca      600

ctgcagaact atagcaactg gaatgagggg gaacccagcg acccctatgg tcatgaggac      660

tgtgtggaga tgctgagctc tggcagatgg aatgacacag agtgccatct taccatgtac      720

tttgtctgtg agttcatcaa gaagaaaaag                                       750


<210>  3401
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  3401
cagccggctg gcgatgacgc ctgctctgtg cagatcctcg tccctggcct caaaggggat       60

gcgggagaga agggagacaa aggcgccccc ggacggcctg gaagagtcgg ccccacggga      120

gaaaaaggag acatggggga caaaggacag aaaggcagtg tgggtcgtca tggaaaaatt      180

ggtcccattg gctctaaagg tgagaaagga gattccggtg acataggacc ccctggtcct      240

aatggagaac caggcctccc atgtgagtgc agccagctgc gcaaggccat cggggagatg      300

gacaaccagg tctctcagct gaccagcgag ctcaagttca tcaagaatgc tgtcgccggt      360

gtgcgcgaga cggagagcaa gatctacctg ctggtgaagg aggagaagcg ctacgcggac      420

gcccagctgt cctgccaggg ccgcgggggc acgctgagca tgcccaagga cgaggctgcc      480

aatggcctga tggccgcata cctggcgcaa gccggcctgg cccgtgtctt catcggcatc      540

aacgacctgg agaaggaggg cgccttcgtg tactctgacc actcccccat gcggaccttc      600

aacaagtggc gcagcggtga gcccaacaat gcctacgacg aggaggactg cgtggagatg      660

gtggcctcgg gcggctggaa cgacgtggcc tgccacacca ccatgtactt catgtgtgag      720

tttgacaagg agaacatg                                                    738


<210>  3402
<211>  2052
<212>  DNA
<213>  Homo Sapiens

<400>  3402
tataaagttg tagagaaaat ggacaatgtc acaggtggca tggaaacatc tcgccaaacc       60

tatgatgaca agctcacagc agtggaaagt gacctggaaa aattaggtga ccaaactggg      120

aagaaagcta tcagcaccaa ctcagaactc tccaccttca gatcagacat tctagatctc      180

cgtcagcaac ttcgtgagat tacagaaaaa accagcaaga acaaggatac gctggagaag      240

ttacaggcga gcggggatgc tctggtggac aggcagagtc aattgaaaga aactttggag      300

aataactctt tcctcatcac cactgtaaac aaaaccctcc aggcgtataa tggctatgtc      360

acgaatctgc agcaagatac cagcgtgctc cagggcaatc tgcagaacca aatgtattct      420

cataatgtgg tcatcatgaa cctcaacaac ctgaacctga cccaggtgca gcagaggaac      480

ctcatcacga atctgcagcg gtctgtggat gacacaagcc aggctatcca gcgaatcaag      540

aacgactttc aaaatctgca gcaggttttt cttcaagcca agaaggacac ggattggctg      600

aaggagaaag tgcagagctt gcagacgctg gctgccaaca actctgcgtt ggccaaagcc      660

aacaacgaca ccctggagga tatgaacagc cagctcaact cattcacagg tcagatggag      720

aacatcacca ctatctctca agccaacgag cagaacctga aagacctgca ggacttacac      780

aaagatgcag agaatagaac agccatcaag ttcaaccaac tggaggaacg cttccagctc      840

tttgagacgg atattgtgaa catcattagc aatatcagtt acacagccca ccacctgcgg      900

acgctgacca gcaatctaaa tgaagtcagg accacttgca cagataccct taccaaacac      960

acagatgatc tgacctcctt gaataatacc ctggccaaca tccgtttgga ttctgtttct     1020

ctcaggatgc aacaagattt gatgaggtcg aggttagaca ctgaagtagc caacttatca     1080

gtgattatgg aagaaatgaa gctagtagac tccaagcatg gtcagctcat caagaatttt     1140

acaatactac aaggtccacc gggccccagg ggtccaagag gtgacagagg atcccaggga     1200

ccccctggcc caactggcaa caagggacag aaaggagaga agggggagcc tggaccacct     1260

ggccctgcgg gtgagagagg cccaattgga ccagctggtc cccccggaga gcgtggcggc     1320

aaaggatcta aaggctccca gggccccaaa ggctcccgtg gttcccctgg gaagcccggc     1380

cctcagggcc ccagtgggga cccaggcccc ccgggcccac caggcaaaga gggactcccc     1440

ggccctcagg gccctcctgg cttccaggga cttcagggca ccgttgggga gcctggggtg     1500

cctggacctc ggggactgcc aggcttgcct ggggtaccag gcatgccagg ccccaagggc     1560

ccccccggcc ctcctggccc atcaggagcg gtggtgcccc tggccctgca gaatgagcca     1620

accccggcac cggaggacaa tagctgcccg cctcactgga agaacttcac agacaaatgc     1680

tactattttt cagttgagaa agaaattttt gaggatgcaa agcttttctg tgaagacaag     1740

tcttcacatc ttgttttcat aaacactaga gaggaacagc aatggataaa aaaacagatg     1800

gtagggagag agagccactg gatcggcctc acagactcag agcgtgaaaa tgaatggaag     1860

tggctggatg ggacatctcc agactacaaa aattggaaag ctggacagcc ggataactgg     1920

ggtcatggcc atgggccagg agaagactgt gctgggttga tttatgctgg gcagtggaac     1980

gatttccaat gtgaagacgt caataacttc atttgcgaaa aagacaggga gacagtactg     2040

tcatctgcat ta                                                         2052


<210>  3403
<211>  2211
<212>  DNA
<213>  Homo Sapiens

<400>  3403
cagggccaga gcccgttggg ctcagacctg ggcccgcaga tgcttcggga actgcaggaa       60

accaacgcgg cgctgcagga cgtgcgggag ctgctgcggc agcaggtcag ggagatcacg      120

ttcctgaaaa acacggtgat ggagtgtgac gcgtgcggga tgcagcagtc agtacgcacc      180

ggcctaccca gcgtgcggcc cctgctccac tgcgcgcccg gcttctgctt ccccggcgtg      240

gcctgcatcc agacggagag cggcgcgcgc tgcggcccct gccccgcggg cttcacgggc      300

aacggctcgc actgcaccga cgtcaacgag tgcaacgccc acccctgctt cccccgagtc      360

cgctgtatca acaccagccc ggggttccgc tgcgaggctt gcccgccggg gtacagcggc      420

cccacccacc agggcgtggg gctggctttc gccaaggcca acaagcaggt ttgcacggac      480

atcaacgagt gtgagaccgg gcaacataac tgcgtcccca actccgtgtg catcaacacc      540

cggggctcct tccagtgcgg cccgtgccag cccggcttcg tgggcgacca ggcgtccggc      600

tgccagcggc gcgcacagcg cttctgcccc gacggctcgc ccagcgagtg ccacgagcat      660

gcagactgcg tcctagagcg cgatggctcg cggtcgtgcg tgtgtgccgt tggctgggcc      720

ggcaacggga tcctctgtgg tcgcgacact gacctagacg gcttcccgga cgagaagctg      780

cgctgcccgg agcgccagtg ccgtaaggac aactgcgtga ctgtgcccaa ctcagggcag      840

gaggatgtgg accgcgatgg catcggagac gcctgcgatc cggatgccga cggggacggg      900

gtccccaatg aaaaggacaa ctgcccgctg gtgcggaacc cagaccagcg caacacggac      960

gaggacaagt ggggcgatgc gtgcgacaac tgccggtccc agaagaacga cgaccaaaag     1020

gacacagacc aggacggccg gggcgatgcg tgcgacgacg acatcgacgg cgaccggatc     1080

cgcaaccagg ccgacaactg ccctagggta cccaactcag accagaagga cagtgatggc     1140

gatggtatag gggatgcctg tgacaactgt ccccagaaga gcaacccgga tcaggcggat     1200

gtggaccacg actttgtggg agatgcttgt gacagcgatc aagaccagga tggagacgga     1260

catcaggact ctcgggacaa ctgtcccacg gtgcctaaca gtgcccagga ggactcagac     1320

cacgatggcc agggtgatgc ctgcgacgac gacgacgaca atgacggagt ccctgacagt     1380

cgggacaact gccgcctggt gcctaacccc ggccaggagg acgcggacag ggacggcgtg     1440

ggcgacgtgt gccaggacga ctttgatgca gacaaggtgg tagacaagat cgacgtgtgt     1500

ccggagaacg ctgaagtcac gctcaccgac ttcagggcct tccagacagt cgtgctggac     1560

ccggagggtg acgcgcagat tgaccccaac tgggtggtgc tcaaccaggg aagggagatc     1620

gtgcagacaa tgaacagcga cccaggcctg gctgtgggtt acactgcctt caatggcgtg     1680

gacttcgagg gcacgttcca tgtgaacacg gtcacggatg acgactatgc gggcttcatc     1740

tttggctacc aggacagctc cagcttctac gtggtcatgt ggaagcagat ggagcaaacg     1800

tattggcagg cgaacccctt ccgtgctgtg gccgagcctg gcatccaact caaggctgtg     1860

aagtcttcca caggccccgg ggaacagctg cggaacgctc tgtggcatac aggagacaca     1920

gagtcccagg tgcggctgct gtggaaggac ccgcgaaacg tgggttggaa ggacaagaag     1980

tcctatcgtt ggttcctgca gcaccggccc caagtgggct acatcagggt gcgattctat     2040

gagggccctg agctggtggc cgacagcaac gtggtcttgg acacaaccat gcggggtggc     2100

cgcctggggg tcttctgctt ctcccaggag aacatcatct gggccaacct gcgttaccgc     2160

tgcaatgaca ccatcccaga ggactatgag acccatcagc tgcggcaagc c              2211


<210>  3404
<211>  1296
<212>  DNA
<213>  Homo Sapiens

<400>  3404
gcgcagcctc aggccccggg ttacttgatt gcagctccct ctgtttttcg cgcgggcgtg       60

gaggaagtca tcagcgtgac catctttaac tctccaaggg aagtcacggt ccaggctcag      120

ctggtggccc agggtgagcc ggtggtgcag agccagggag ccatcctgga taaagggaca      180

atcaaactca aggtgcccac gggcctccgg ggccaagcgc ttctgaaagt gtggggccgc      240

ggctggcagg cggaggaggg gcccctcttt cacaaccaga cctcggtgac cgtggacggc      300

cggggcgctt ctgtattcat ccagacggac aagcctgtgt acagacccca gcaccgagtg      360

ctcataagca tcttcaccgt ctctccaaat ctgaggcctg tcaacgagaa gctggaagcc      420

tacatcctgg acccccgagg ctctcggatg atagagtgga gacacttaaa gccgttctgc      480

tgcggcatca ccaacatgag cttccccttg tccgaccagc ctgtgttggg agaatggttc      540

atttttgttg aaatgcaagg ccacgcgtac aacaagtctt ttgaagttca gaagtatgtg      600

ttgcccaagt ttgagcttct gattgacccg ccccggtata tccaagacct ggacgcctgt      660

gagacaggca ctgtgcgggc caggtatacc tttgggaaac ctgtggctgg tgccttaacg      720

atcaacatga ctgttaatgg tgtagggtac tacagccacg aggtgggacg ccctgtcctc      780

agaacaacca agatcctcgg ctcccaggac ttcgacatct gcgtgaggga catgatccca      840

gcggacgtcc ctgagcactt ccggggcagg gtcagcatct gggccatggt gaccagtgtg      900

gacgggagcc agcaggtcgc gttcgatgac tccacccccg tgcagaggca gctggtggac      960

atccggtact ccaaggacac gaggaagcag ttcaagccgg gcctggccta cgtggggaag     1020

gtggagctat cctaccccga tggcagccca gctgaggggg tgacggtcca gattaaggca     1080

gagctgacac caaaggataa catctacacc agtgaagttg tgtcccagcg tggactagtg     1140

gggtttgaaa tcccctccat ccccacgtca gcccagcacg tgtggctgga ggttttccag     1200

gaactggaag attatgatgt ttctgattcc tttggcgtgt ccagggagga tggtcctttt     1260

tggtgggctg ggctgacggc acaacgacgc cggcgc                               1296


<210>  3405
<211>  1572
<212>  DNA
<213>  Homo Sapiens

<400>  3405
tgtcccatgg gttgtgactg cttcgtccag gaggtgttct gctcagatga ggagcttgcc       60

accgtcccgc tggacatccc gccatatacg aaaaacatca tctttgtgga gacctcgttc      120

accacattgg aaaccagagc ttttggcagt aaccccaact tgaccaaggt ggtcttcctc      180

aacactcagc tctgccagtt taggccggat gcctttgggg ggctgcccag gctggaggac      240

ctggaggtca caggcagtag cttcttgaac ctcagcacca acatcttctc caacctgacc      300

tcgctgggca agctcaccct caacttcaac atgctggagg ctctgcccga gggtcttttc      360

cagcacctgg ctgccctgga gtccctccac ctgcagggga accagctcca ggccctgccc      420

aggaggctct tccagcctct gacccatctg aagacactca acctggccca gaacctcctg      480

gcccagctcc cggaggagct gttccaccca ctcaccagcc tgcagaccct gaagctgagc      540

aacaacgcgc tctctggtct cccccagggt gtgtttggca aactgggcag cctgcaggag      600

ctcttcctgg acagcaacaa catctcggag ctgccccctc aggtgttctc ccagctcttc      660

tgcctagaga ggctgtggct gcaacgcaac gccatcacgc acctgccgct ctccatcttt      720

gcctccctgg gtaatctgac ctttctgagc ttgcagtgga acatgcttcg ggtcctgcct      780

gccggcctct ttgcccacac cccatgcctg gttggcctgt ctctgaccca taaccagctg      840

gagactgtcg ctgagggcac ctttgcccac ctgtccaacc tgcgttccct catgctctca      900

tacaatgcca ttacccacct cccagctggc atcttcagag acctggagga gttggtcaaa      960

ctctacctgg gcagcaacaa ccttacggcg ctgcacccag ccctcttcca gaacctgtcc     1020

aagctggagc tgctcagcct ctccaagaac cagctgacca cacttccgga gggcatcttc     1080

gacaccaact acaacctgtt caacctggcc ctgcacggta acccctggca gtgcgactgc     1140

cacctggcct acctcttcaa ctggctgcag cagtacaccg atcggctcct gaacatccag     1200

acctactgcg ctggccctgc ctacctcaaa ggccaggtgg tgcccgcctt gaatgagaag     1260

cagctggtgt gtcccgtcac ccgggaccac ttgggcttcc aggtcacgtg gccggacgaa     1320

agcaaggcag ggggcagctg ggatctggct gtgcaggaaa gggcagcccg gagccagtgc     1380

acctacagca accccgaggg caccgtggtg ctcgcctgtg accaggccca gtgtcgctgg     1440

ctgaacgtcc agctctctcc ttggcagggc tccctgggac tgcagtacaa tgctagtcag     1500

gagtgggacc tgaggtcgag ctgcggttct ctgcggctca ccgtgtctat cgaggctcgg     1560

gcagcagggc cc                                                         1572


<210>  3406
<211>  3966
<212>  DNA
<213>  Homo Sapiens

<400>  3406
ttttgcaata aaaacaacac caggtgcctc tcaaattctt gccaaaacaa ttctacatgc       60

aaagattttt caaaagacaa tgattgttct tgttcagaca cagccaataa tttggacaaa      120

gactgtgaca acatgaaaga cccttgcttc tccaatccct gtcaaggaag tgccacttgt      180

gtgaacaccc caggagaaag gagctttctg tgcaaatgtc ctcctgggta cagtgggaca      240

atctgtgaaa ctaccattgg ttcctgtggc aagaactcct gccaacatgg aggtatttgc      300

catcaggacc ctatttatcc tgtctgcatc tgccctgctg gatatgctgg aagattctgt      360

gagatagatc acgatgagtg tgcttccagc ccttgccaaa atggggccgt gtgccaggat      420

ggaattgatg gttactcctg cttctgtgtc ccaggatatc aaggcagaca ctgcgacttg      480

gaagtggatg aatgtgcttc agatccctgc aagaacgagg ctacatgcct caatgaaata      540

ggaagatata cttgtatctg tccccacaat tattctggtg taaactgtga attggaaatt      600

gacgaatgtt ggtcccagcc ttgtttaaat ggtgcaactt gtcaggatgc tctgggggcc      660

tatttctgcg actgtgcccc tggattcctg ggggatcact gtgaactcaa cactgatgag      720

tgtgccagtc aaccttgtct ccatggaggg ctgtgtgtgg atggagaaaa cagatatagc      780

tgtaactgca cgggtagtgg attcacaggg acacactgtg agaccttgat gcctctttgt      840

tggtcaaaac cttgtcacaa taatgctaca tgtgaggaca gtgttgacaa ttacacttgt      900

cactgctggc ctggatacac aggtgcccag tgtgagatcg acctcaatga atgcaatagt      960

aacccctgcc agtccaatgg ggaatgtgtg gagctgtcct cagagaaaca atatggacgc     1020

atcactggac tgccttcttc tttcagctac catgaagcct caggttatgt ctgtatctgt     1080

cagcctggat tcacaggaat ccactgcgaa gaagacgtca atgaatgttc ttcaaaccct     1140

tgccaaaatg gtggtacttg tgagaacttg cctgggaatt atacttgcca ttgcccattt     1200

gataaccttt ctagaacttt ttatggagga agggactgtt ctgatattct cctgggctgt     1260

acccatcagc aatgtctaaa taatggaaca tgcatccctc acttccaaga tggccagcat     1320

ggattcagct gcctgtgtcc atctggctac accgggtccc tgtgtgaaat cgcaaccaca     1380

ctttcatttg agggcgatgg cttcctgtgg gtcaaaagtg gctcagtgac aaccaagggc     1440

tcagtttgta acatagccct caggtttcag actgttcagc caatggctct tctacttttc     1500

cgaagcaaca gggatgtgtt tgtgaagctg gagctgctaa gtggctacat tcacttatca     1560

attcaggtca ataatcagtc aaaggtgctt ctgttcattt cccacaacac cagcgatgga     1620

gagtggcatt tcgtggaggt aatatttgca gaggctgtga cccttacctt aatcgacgac     1680

tcctgtaagg agaaatgcat cgcgaaagct cctactccac ttgaaagtga tcaatcaata     1740

tgtgcttttc agaactcctt tttgggtggt ttaccagtgg gaatgaccag caatggtgtt     1800

gctctgctta acttctataa tatgccatcc acaccttcgt ttgtaggctg tctccaagac     1860

attaaaattg attggaatca cattaccctg gagaacatct cgtctggctc atcattaaat     1920

gtcaaggcag gctgtgtgag aaaggattgg tgtgaaagcc aaccttgtca aagcagagga     1980

cgctgcatca acttgtggct gagttaccag tgtgactgcc acaggcccta tgaaggcccc     2040

aactgtctga gagagtatgt ggcaggcaga tttggccagg atgactccac tggttatgtc     2100

atctttactc ttgatgagag ctatggagac accatcagcc tctccatgtt tgtccgaacg     2160

cttcaaccat caggcttact tctagctttg gaaaacagca cttatcaata tatccgtgtc     2220

tggctagagc gcggcagact agcaatgctg actccaaact ctcccaaatt agtagtaaaa     2280

tttgttctta atgatggaaa tgtccacttg atatctttga aaatcaagcc atataaaatt     2340

gaactgtatc agtcttcaca aaacctagga tttatttctg cttctacgtg gaaaatcgaa     2400

aagggagatg tcatctacat tggtggccta cctgacaagc aagagactga acttaatggt     2460

ggattcttca aaggctgtat ccaagatgta agactaaaca accaaaatct ggaattcttt     2520

ccaaatccaa caaacaatgc atctctcaat ccagttcttg tcaatgtaac ccaaggctgt     2580

gctggagaca acagctgcaa gtccaacccc tgtcacaatg gaggtgtttg ccattcccgg     2640

tgggatgact tctcctgttc ctgtcctgcc ctcacaagtg ggaaagcctg tgaggaggtt     2700

cagtggtgtg gattcagccc gtgtcctcac ggagcccagt gccagccggt gcttcaagga     2760

tttgaatgta ttgcaaatgc tgtttttaat ggacaaagcg gtcaaatatt attcagaagc     2820

aatgggaata ttaccagaga actcaccaat atcacatttg gtttcagaac aagggatgca     2880

aatgtaataa tattgcatgc agaaaaagag cctgaatttc ttaatattag cattcaagat     2940

tccagattat tctttcaatt gcaaagtggc aacagctttt atatgctaag tctgacaagt     3000

ttgcagtcag tgaatgatgg cacatggcac gaagtgaccc tttccatgac agacccactg     3060

tcccagacct ccaggtggca aatggaagtg gacaacgaaa caccttttgt gaccagcaca     3120

attgctactg gaagcctcaa ctttttgaag gataatacag atatttatgt gggagacaga     3180

gctattgaca atataaaggg cctgcaaggg tgtctaagta caatagaaat cggaggcatt     3240

tatctctctt actttgaaaa tgttcatggt ttcattaata aacctcagga agagcaattt     3300

ctcaaaatct ctaccaattc agtggtcact ggctgtttgc agttaaatgt ctgcaactcc     3360

aacccctgtt tgcatggagg aaactgtgaa gacatctata gctcttatca ttgctcctgt     3420

cccttgggat ggtcagggaa acactgtgaa ctcaacatcg atgaatgctt ttcaaacccc     3480

tgtatccatg gcaactgctc tgacagagtt gcagcctacc actgcacatg tgagcctgga     3540

tacactggtg tgaactgtga agtggatata gacaactgcc agagtcacca gtgtgcaaat     3600

ggagccacct gcattagtca tactaatggc tattcttgcc tctgttttgg aaattttaca     3660

ggaaaatttt gcagacagag cagattaccc tcaacagtct gtgggaatga gaagacaaat     3720

ctcacttgct acaatggagg caactgcaca gagttccaga ctgaattaaa atgtatgtgc     3780

cggccaggtt ttactggaga atggtgtgaa aaggacattg atgagtgtgc ctctgatccg     3840

tgtgtcaatg gaggtctgtg ccaggactta ctcaacaaat tccagtgcct ctgtgatgtt     3900

gcctttgctg gcgagcgctg cgaggtggac ttggcagatg acttgatctc cgacattttc     3960

accact                                                                3966


<210>  3407
<211>  1179
<212>  DNA
<213>  Homo Sapiens

<400>  3407
cagccctctc cacctcccca gtcttctccc ccgcctcagc cccatccgtg tcatacctgc       60

cggggactgg ttgacagctt taacaagggc ctggagagaa ccatccggga caactttgga      120

ggtggaaaca ctgcctggga ggaagagaat ttgtccaaat acaaagacag tgagacccgc      180

ctggtagagg tgctggaggg tgtgtgcagc aagtcagact tcgagtgcca ccgcctgctg      240

gagctgagtg aggagctggt ggagagctgg tggtttcaca agcagcagga ggccccggac      300

ctcttccagt ggctgtgctc agattccctg aagctctgct gccccgcagg caccttcggg      360

ccctcctgcc ttccctgtcc tgggggaaca gagaggccct gcggtggcta cgggcagtgt      420

gaaggagaag ggacacgagg gggcagcggg cactgtgact gccaagccgg ctacgggggt      480

gaggcctgtg gccagtgtgg ccttggctac tttgaggcag aacgcaacgc cagccatctg      540

gtatgttcgg cttgttttgg cccctgtgcc cgatgctcag gacctgagga atcaaactgt      600

ttgcaatgca agaagggctg ggccctgcat cacctcaagt gtgtagacat tgatgagtgt      660

ggcacagagg gagccaactg tggagctgac caattctgcg tgaacactga gggctcctat      720

gagtgccgag actgtgccaa ggcctgccta ggctgcatgg gggcagggcc aggtcgctgt      780

aagaagtgta gccctggcta tcagcaggtg ggctccaagt gtctcgatgt ggatgagtgt      840

gagacagagg tgtgtccggg agagaacaag cagtgtgaaa acaccgaggg cggttatcgc      900

tgcatctgtg ccgagggcta caagcagatg gaaggcatct gtgtgaagga gcagatccca      960

ggtgcattcc ccatcttaac tgatttaacc cctgaaacaa cccgacgctg gaagttgggt     1020

tctcatcccc actctacata tgtaaaaatg aagatgcaga gagatgaagc tactttccca     1080

gggctatatg gcaagcaagt cgcaaagctg ggatcccaat ccagacagtc tgaccgtgga     1140

acgagactca tacacagtca gcaggcttct tctcagaga                            1179


<210>  3408
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  3408
gccaagaagc cgacgccctg ccaccggtgc cgggggctgg tggacaagtt taaccagggg       60

atggtggaca ccgcaaagaa gaactttggc ggcgggaaca cggcttggga ggaaaagacg      120

ctgtccaagt acgagtccag cgagattcgc ctgctggaga tcctggaggg gctgtgcgag      180

agcagcgact tcgaatgcaa ccagatgcta gaggcgcagg aggagcacct ggaggcctgg      240

tggctgcagc tgaagagcga atatcctgac ttattcgagt ggttttgtgt gaagacactg      300

aaagtgtgct gctctccagg aacctacggt cccgactgtc tcgcatgcca gggcggatcc      360

cagaggccct gcagcgggaa tggccactgc agcggagatg ggagcagaca gggcgacggg      420

tcctgccggt gccacatggg gtaccagggc ccgctgtgca ctgactgcat ggacggctac      480

ttcagctcgc tccggaacga gacccacagc atctgcacag cctgtgacga gtcctgcaag      540

acgtgctcgg gcctgaccaa cagagactgc ggcgagtgtg aagtgggctg ggtgctggac      600

gagggcgcct gtgtggatgt ggacgagtgt gcggccgagc cgcctccctg cagcgctgcg      660

cagttctgta agaacgccaa cggctcctac acgtgcgaag agtgtgactc cagctgtgtg      720

ggctgcacag gggaaggccc aggaaactgt aaagagtgta tctctggcta cgcgagggag      780

cacggacagt gtgcagatgt ggacgagtgc gcactagcag aaaaaacctg tgtgaggaaa      840

aacgaaaact gctacaatac tccagggagc tacgtctgtg tgtgtcctga cggcttcgaa      900

ggaacggaag atgcctgtgt gccgccggca gaggctgaag ccacagaagg agaaagcccg      960

acacagctgc cctcccgcga agacctg                                          987


<210>  3409
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  3409
gcccacacag ctgtgatcag tccccaggat cccacgcttc tcatcggctc ctccctgctg       60

gccacctgct cagtgcacgg agacccacca ggagccaccg ccgagggcct ctactggacc      120

ctcaacgggc gccgcctgcc ccctgagctc tcccgtgtac tcaacgcctc caccttggct      180

ctggccctgg ccaacctcaa tgggtccagg cagcggtcgg gggacaacct cgtgtgccac      240

gcccgtgacg gcagcatcct ggctggctcc tgcctctatg ttggcctgcc cccagagaaa      300

cccgtcaaca tcagctgctg gtccaagaac atgaaggact tgacctgccg ctggacgcca      360

ggggcccacg gggagacctt cctccacacc aactactccc tcaagtacaa gcttaggtgg      420

tatggccagg acaacacatg tgaggagtac cacacagtgg ggccccactc ctgccacatc      480

cccaaggacc tggctctctt tacgccctat gagatctggg tggaggccac caaccgcctg      540

ggctctgccc gctccgatgt actcacgctg gatatcctgg atgtggtgac cacggacccc      600

ccgcccgacg tgcacgtgag ccgcgtcggg ggcctggagg accagctgag cgtgcgctgg      660

gtgtcgccac ccgccctcaa ggatttcctc tttcaagcca aataccagat ccgctaccga      720

gtggaggaca gtgtggactg gaaggtggtg gacgatgtga gcaaccagac ctcctgccgc      780

ctggccggcc tgaaacccgg caccgtgtac ttcgtgcaag tgcgctgcaa cccctttggc      840

atctatggct ccaagaaagc cgggatctgg agtgagtgga gccaccccac agccgcctcc      900

actccccgca gtgagcgccc gggcccgggc ggcggggcgt gcgaaccgcg gggcggagag      960

ccgagctcgg ggccggtgcg gcgcgagctc aagcagttcc tgggctggct caagaagcac     1020

gcgtactgct ccaatctcag cttccgcctc tacgaccagt ggcgagcctg gatgcagaag     1080

tcgcacaaga cccgcaacca ggacgagggg atcctgccct cgggcagacg gggcacggcg     1140

agaggtcctg ccaga                                                      1155


<210>  3410
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  3410
caggggggcg cagccgaagg agtgcaaatc caaatcatat acttcaacct tgagacggtg       60

caagtaacct ggaacgcctc aaaatactct aggactaacc taacctttca ttataggttt      120

aacggggatg aagcctatga ccaatgcaca aattatctat tacaagaagg acatacatct      180

gggtgtttgt tggacgcaga acaacgtgat gacatactat acttttcaat aagaaacggg      240

acccatcctg tattcactgc ctcaaggtgg atggtgtact acctaaagcc gtctagccct      300

aaacacgtca ggttcagttg gcaccaagac gccgttacag taacatgcag cgatttatcc      360

tacggcgact tgctttacga ggtgcaatac aggtccccat tcgacacgga gtggcagtct      420

aaacaggaaa acacttgcaa tgttactata gagggacttg acgccgaaaa atgttacagc      480

ttctgggtga gggttaaagc tatggaggac gtttatggcc cagataccta tccgagcgat      540

tggagtgagg tcacgtgttg gcagcgtgga gaaattagag acgcatgtgc tgagacccca      600

acacctccaa agcctaaact tagtaaa                                          627


<210>  3411
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  3411
gacaccaatg aatgcatcca gttcccattc gtgtgccctc gagacaagcc cgtatgtgtc       60

aacacctatg gaagctacag gtgccggacc aacaagaagt gcagtcgggg ctacgagccc      120

aacgaggatg gcacagcctg cgtggggact ctcggccagt caccgggccc ccgccccacc      180

acccccaccg ctgctgctgc cactgccgct gctgctgccg ctgctggagc tgccactgct      240

gcaccggtcc tcgtagatgg agatctcaat ctggggtcgg tggttaagga gagctgcgag      300

cccagctgc                                                              309


<210>  3412
<211>  810
<212>  DNA
<213>  Homo Sapiens

<400>  3412
tctctgacta accacacaga aaccatcacc gtggaggaag gccagacgct cactctaaag       60

tgtgtcactt ctctgaggaa gaactcctcc ctccagtggc tgaccccctc agggttcacc      120

atttttttaa atgagtatcc tgttttaaaa aattccaaat accagcttct tcatcactcg      180

gccaatcagc tctccatcac tgtgcctaac gtaaccctgc aagatgaagg cgtgtacaag      240

tgcttacatt acagcgactc tgtaagcaca aaggaagtga aagtgattgt gctggcaact      300

cctttcaagc caatcctgga agcttcagtt atcagaaagc aaaatggaga agaacatgtt      360

gtactcatgt gctccaccat gagaagcaag ccccctccgc agataacctg gctacttggg      420

aatagcatgg aagtgtccgg tggaacgctc catgaatttg aaactgatgg gaagaaatgt      480

aatactacca gcactctcat aatccacact tatggcaaaa attcaacggt ggactgcatt      540

atccgacaca gaggcctgca agggagaaaa ctagtagcac ccttccggtt tgaagatttg      600

gttactgatg aagagacagc ttcagatgct ctggagagaa actctctatc ctctcaagac      660

ccacagcagc ccaccagtac tgtctcagta acggaagatt ctagtacatc ggagattgac      720

aaggaagaga aagaacaaac cactcaagat cctgacttga ccaccgaagc aaatcctcag      780

tatttaggac tggcaagaaa gaaaagtggc                                       810


<210>  3413
<211>  1494
<212>  DNA
<213>  Homo Sapiens

<400>  3413
atcccagtga tagagcccag tgtccccgag ctggtcgtga agccaggagc aacggtgacc       60

ttgcgatgtg tgggcaatgg cagcgtggaa tgggatggcc ccccatcacc tcactggacc      120

ctgtactctg atggctccag cagcatcctc agcaccaaca acgctacctt ccaaaacacg      180

gggacctatc gctgcactga gcctggagac cccctgggag gcagcgccgc catccacctc      240

tatgtcaaag accctgcccg gccctggaac gtgctagcac aggaggtggt cgtgttcgag      300

gaccaggacg cactactgcc ctgtctgctc acagacccgg tgctggaagc aggcgtctcg      360

ctggtgcgtg tgcgtggccg gcccctcatg cgccacacca actactcctt ctcgccctgg      420

catggcttca ccatccacag ggccaagttc attcagagcc aggactatca atgcagtgcc      480

ctgatgggtg gcaggaaggt gatgtccatc agcatccggc tgaaagtgca gaaagtcatc      540

ccagggcccc cagccttgac actggtgcct gcagagctgg tgcggattcg aggggaggct      600

gcccagatcg tgtgctcagc cagcagcgtt gatgttaact ttgatgtctt cctccaacac      660

aacaacacca agctcgcaat ccatcaacaa tctgactttc ataataaccg ttaccaaaaa      720

gtcctgaccc tcaacctcga tcaagtagat ttccaacatg ccggcaacta ctcctgcgtg      780

gccagcaacg tgcagggcaa gcactccacc tccatgttct tccgggtggt agagagtgcc      840

tacttgaact tgagctctga gcagaacctc atccaggagg tgaccgtggg ggaggggctc      900

aacctcaaag tcatggtgga ggcctaccca ggcctgcaag gttttaactg gacctacctg      960

ggaccctttt ctgaccacca gcctgagccc aagcttgcta atgttaccac caaggacaca     1020

tacaggcaca ccttcaccct ctctctgccc cgcctgaagc cctctgaggc tggccgctac     1080

tccttcctgg ccagaaaccc aggaggctgg agagctctga cgtttgagct cacccttcga     1140

taccccccag aggtaagcgt catatggaca ttcatcaacg gctctggcac ccttttgtgt     1200

gctgcctctg ggtaccccca gcccaacgtg acatggctgc agtgcagtgg ccacactgat     1260

aggtgtgatg aggcccaagt gctgcaggtc tgggatgacc cataccctga ggtcctgagc     1320

caggagccct tccacaaggt gacggtgcag agcctgctga ctgttgagac cttagagcac     1380

aaccaaacct acgagtgcag ggcccacaac agcgtgggga gtggctcctg ggccttcata     1440

cccatctctg caggagccca cacgcatccc ccggatgagt tcctcttcac acca           1494


<210>  3414
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  3414
gcacccgccc gctcgcccag ccccagcacg cagccctggg agcatgtgaa tgccatccag       60

gaggcccggc gtctcctgaa cctgagtaga gacactgctg ctgagatgaa tgaaacagta      120

gaagtcatct cagaaatgtt tgacctccag gagccgacct gcctacagac ccgcctggag      180

ctgtacaagc agggcctgcg gggcagcctc accaagctca agggcccctt gaccatgatg      240

gccagccact acaagcagca ctgccctcca accccggaaa cttcctgtgc aacccagatt      300

atcacctttg aaagtttcaa agagaacctg aaggactttc tgcttgtcat cccctttgac      360

tgctgggagc cagtccagga g                                                381


<210>  3415
<211>  894
<212>  DNA
<213>  Homo Sapiens

<400>  3415
gagaaatcgg atctgcgaac agtggcacca gcctctagtc tcaatgtgag gtttgactcc       60

aggacgatga atttaagctg ggactgccaa gaaaacacaa ccttcagcaa gtgtttctta      120

actgacaaga agaacagagt cgtggaaccc aggctcagta acaacgaatg ttcgtgcaca      180

tttcgtgaaa tttgtctgca tgaaggagtc acatttgagg ttcacgtgaa tactagtcaa      240

agaggatttc aacagaaact gctttatcca aattcaggaa gggagggtac cgctgctcag      300

aatttctcct gtttcatcta caatgcggat ttaatgaact gtacctgggc gaggggtccg      360

acggcccccc gtgacgtcca gtattttttg tacatacgaa actcaaagag aaggagggag      420

atccggtgtc cttattacat acaagactca ggaacccatg tgggatgtca cctggataac      480

ctgtcaggat taacgtctcg caattacttt ctggttaacg gaaccagccg agaaattggc      540

atccaattct ttgattcact tttggacaca aagaaaatag aacgattcaa ccctcccagc      600

aatgtcaccg tacgttgcaa cacgacgcac tgcctcgtac ggtggaaaca gcccaggacc      660

tatcagaagc tgtcgtacct ggactttcag taccagctgg acgtccacag aaagaatacc      720

cagcctggca cggaaaacct actgattaat gtttctggtg atttggaaaa tagatacaac      780

tttccaagct ctgagcccag agcaaaacac agtgtgaaga tcagagctgc agacgtccgc      840

atcttgaatt ggagctcctg gagtgaagcc attgaatttg gttctgacga cggg            894


<210>  3416
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  3416
gaagaaacca tcccgctgca gaccctgcgc tgctacaacg actacaccag ccacatcacc       60

tgcaggtggg cagacaccca ggatgcccag cggctcgtca acgtgaccct cattcgccgg      120

gtgaatgagg acctcctgga gccagtgtcc tgtgacctca gtgatgacat gccctggtca      180

gcctgccccc atccccgctg cgtgcccagg agatgtgtca ttccctgcca gagttttgtc      240

gtcactgacg ttgactactt ctcattccaa ccagacaggc ctctgggcac ccggctcacc      300

gtcactctga cccagcatgt ccagcctcct gagcccaggg acctgcagat cagcaccgac      360

caggaccact tcctgctgac ctggagtgtg gcccttggga gtccccagag ccactggttg      420

tccccagggg atctggagtt tgaggtggtc tacaagcggc ttcaggactc ttgggaggac      480

gcagccatcc tcctctccaa cacctcccag gccaccctgg ggccagagca cctcatgccc      540

agcagcacct acgtggcccg agtacggacc cgcctggccc caggttctcg gctctcagga      600

cgtcccagca agtggagccc agaggtttgc tgggactccc agccagggga tgaggcccag      660

ccccagaacc tggagtgctt ctttgacggg gccgccgtgc tcagctgctc ctgggaggtg      720

aggaaggagg tggccagctc ggtctccttt ggcctattct acaagcccag cccagatgca      780

ggctctgctg tgctcctcag ggaggaagag tgctccccag tgctgaggga ggggctcggc      840

agcctccaca ccaggcacca ctgccagatt cccgtgcccg accccgcgac ccacggccaa      900

tacatcgtct ctgttcagcc aaggagggca gagaaacaca taaagagctc agtgaacatc      960

cagatggccc ctccatccct caacgtgacc aaggatggag acagctacag cctgcgctgg     1020

gaaacaatga aaatgcgata cgaacacata gaccacacat ttgagatcca gtacaggaaa     1080

gacacggcca cgtggaagga cagcaagacc gagaccctcc agaacgccca cagcatggcc     1140

ctgccagccc tggagccctc caccaggtac tgggccaggg tgagggtcag gacctcccgc     1200

accggctaca acgggatctg gagcgagtgg agtgaggcgc gctcctggga caccgagtcg     1260

gtgctgccta tgtgg                                                      1275


<210>  3417
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3417
gccacccccc tgggccctgc cagctccctg ccccagagct tcctgctcaa gtgcttagag       60

caagtgagga agatccaggg cgatggcgca gcgctccagg agaagctgtg tgccacctac      120

aagctgtgcc accccgagga gctggtgctg ctcggacact ctctgggcat cccctgggct      180

cccctgagca gctgccccag ccaggccctg cagctggcag gctgcttgag ccaactccat      240

agcggccttt tcctctacca ggggctcctg caggccctgg aagggatctc ccccgagttg      300

ggtcccacct tggacacact gcagctggac gtcgccgact ttgccaccac catctggcag      360

cagatggaag aactgggaat ggcccctgcc ctgcagccca cccagggtgc catgccggcc      420

ttcgcctctg ctttccagcg ccgggcagga ggggtcctag ttgcctccca tctgcagagc      480

ttcctggagg tgtcgtaccg cgttctacgc caccttgccc agccc                      525


<210>  3418
<211>  1809
<212>  DNA
<213>  Homo Sapiens

<400>  3418
gagtgcgggc acatcagtgt ctcagccccc atcgtccacc tgggggatcc catcacagcc       60

tcctgcatca tcaagcagaa ctgcagccat ctggacccgg agccacagat tctgtggaga      120

ctgggagcag agcttcagcc cgggggcagg cagcagcgtc tgtctgatgg gacccaggaa      180

tctatcatca ccctgcccca cctcaaccac actcaggcct ttctctcctg ctgcctgaac      240

tggggcaaca gcctgcagat cctggaccag gttgagctgc gcgcaggcta ccctccagcc      300

ataccccaca acctctcctg cctcatgaac ctcacaacca gcagcctcat ctgccagtgg      360

gagccaggac ctgagaccca cctacccacc agcttcactc tgaagagttt caagagccgg      420

ggcaactgtc agacccaagg ggactccatc ctggactgcg tgcccaagga cgggcagagc      480

cactgctgca tcccacgcaa acacctgctg ttgtaccaga atatgggcat ctgggtgcag      540

gcagagaatg cgctggggac cagcatgtcc ccacaactgt gtcttgatcc catggatgtt      600

gtgaaactgg agccccccat gctgcggacc atggacccca gccctgaagc ggcccctccc      660

caggcaggct gcctacagct gtgctgggag ccatggcagc caggcctgca cataaatcag      720

aagtgtgagc tgcgccacaa gccgcagcgt ggagaagcca gctgggcact ggtgggcccc      780

ctccccttgg aggcccttca gtatgagctc tgcgggctcc tcccagccac ggcctacacc      840

ctgcagatac gctgcatccg ctggcccctg cctggccact ggagcgactg gagccccagc      900

ctggagctga gaactaccga acgggccccc actgtcagac tggacacatg gtggcggcag      960

aggcagctgg accccaggac agtgcagctg ttctggaagc cagtgcccct ggaggaagac     1020

agcggacgga tccaaggtta tgtggtttct tggagaccct caggccaggc tggggccatc     1080

ctgcccctct gcaacaccac agagctcagc tgcaccttcc acctgccttc agaagcccag     1140

gaggtggccc ttgtggccta taactcagcc gggacctctc gtcccactcc ggtggtcttc     1200

tcagaaagca gaggcccagc tctgaccaga ctccatgcca tggcccgaga ccctcacagc     1260

ctctgggtag gctgggagcc ccccaatcca tggcctcagg gctatgtgat tgagtggggc     1320

ctgggccccc ccagcgcgag caatagcaac aagacctgga ggatggaaca gaatgggaga     1380

gccacggggt ttctgctgaa ggagaacatc aggccctttc agctctatga gatcatcgtg     1440

actcccttgt accaggacac catgggaccc tcccagcatg tctatgccta ctctcaagaa     1500

atggctccct cccatgcccc agagctgcat ctaaagcaca ttggcaagac ctgggcacag     1560

ctggagtggg tgcctgagcc ccctgagctg gggaagagcc cccttaccca ctacaccatc     1620

ttctggacca acgctcagaa ccagtccttc tccgccatcc tgaatgcctc ctcccgtggc     1680

tttgtcctcc atggcctgga gcccgccagt ctgtatcaca tccacctcat ggctgccagc     1740

caggctgggg ccaccaacag tacagtcctc accctgatga ccttgacccc agaggggtcg     1800

gagctacac                                                             1809


<210>  3419
<211>  1179
<212>  DNA
<213>  Homo Sapiens

<400>  3419
gtgccggcgc gtgaggcggg cagcgcggtt gaggccgaag agctggtgaa gggcagcccg       60

gcgtgggagc cgcctgccaa cgacacgcgg gaagaagccg gcccaccagc ggctggggaa      120

gatgaggcgt cgtggacggc gcccggtggc gagctggccg ggccagaaga ggtgctgcag      180

gagtcggctg cggtgaccgg caccgcctgg ctggaagctg acagcccagg cctgggagga      240

gtgaccgcag aggcgggcag cggcgatgcc caggcccttc cagctacgct ccaggctccc      300

cacgaggtcc tcgggcagtc aatcatgccc cctgccattc ctgaggctac agaggccagc      360

gggccaccct cccccacccc cggcgacaag ctgagcccag cttctgaact ccccaaggag      420

agccccttgg aggtttggct gaacctgggg ggcagcacac ccgaccctca agggccagag      480

ctgacttacc catttcaggg caccctggag ccccaaccgg catcagatat cattgacatc      540

gactacttcg aaggactgga tggtgagggt cgtggcgcag atctggggag cttcccaggg      600

tcaccaggaa cctcagagaa ccaccctgat actgagggag agaccccttc ctggagcctg      660

cttgacttat acgatgattt cacccccttc gatgaatctg atttctaccc caccacatcc      720

ttttatgatg acttggatga agaggaggag gaagaggagg atgacaaaga tgcagtagga      780

ggtggagacc tagaagatga aaatgagctt ctagtgccca ctgggaagcc tggtctgggg      840

cccgggacag gccagcccac cagtcggtgg catgctgtcc ctccacagca cactctgggg      900

tcggtccccg gcagcagcat cgccctcagg ccccgcccag gagagccagg cagggacttg      960

gcctccagtg aaaatggcac tgagtgccgc agtggctttg tgcggcataa cggctcctgc     1020

cggtcagtgt gcgacctctt cccaagttac tgtcacaatg gcggccagtg ctacctggtg     1080

gagaacatag gggccttctg caggtgcaac acgcaggact acatctggca caaggggatg     1140

cgctgcgagt ccatcatcac cgacttccag gtgatgtgc                            1179


<210>  3420
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  3420
aaagcaatgc acgtggccca gcctgctgtg gtactggcca gcagccgagg catcgccagc       60

tttgtgtgtg agtatgcatc tccaggcaaa gccactgagg tccgggtgac agtgcttcgg      120

caggctgaca gccaggtgac tgaagtctgt gcggcaacct acatgatggg gaatgagttg      180

accttcctag atgattccat ctgcacgggc acctccagtg gaaatcaagt gaacctcact      240

atccaaggac tgagggccat ggacacggga ctctacatct gcaaggtgga gctcatgtac      300

ccaccgccat actacctggg cataggcaac ggaacccaga tttatgtaat tgatccagaa      360

ccgtgcccag attctgac                                                    378


<210>  3421
<211>  945
<212>  DNA
<213>  Homo Sapiens

<400>  3421
cagcaccacg gtgtgacgaa atgcaacatc acgtgcagca agatgacatc aaagatacct       60

gtagctttgc tcatccacta tcaacagaac caggcatcat gcggcaaacg cgcaatcatc      120

ttggagacga gacagcacag gctgttctgt gccgacccga aggagcaatg ggtcaaggac      180

gcgatgcagc atctggaccg ccaggctgct gccctaactc gaaatggcgg caccttcgag      240

aagcagatcg gcgaggtgaa gcccaggacc acccctgccg ccgggggaat ggacgagtct      300

gtggtcctgg agcccgaagc cacaggcgaa agcagtagcc tggagccgac tccttcttcc      360

caggaagcac agagggccct ggggacctcc ccagagctgc cgacgggcgt gactggttcc      420

tcagggacca ggctcccccc gacgccaaag gctcaggatg gagggcctgt gggcacggag      480

cttttccgag tgcctcccgt ctccactgcc gccacgtggc agagttctgc tccccaccaa      540

cctgggccca gcctctgggc tgaggcaaag acctctgagg ccccgtccac ccaggacccc      600

tccacccagg cctccactgc gtcctcccca gccccagagg agaatgctcc gtctgaaggc      660

cagcgtgtgt ggggtcaggg acagagcccc aggccagaga actctctgga gcgggaggag      720

atgggtcccg tgccagcgca cacggatgcc ttccaggact gggggcctgg cagcatggcc      780

cacgtctctg tggtccctgt ctcctcagaa gggaccccca gcagggagcc agtggcttca      840

ggcagctgga cccctaaggc tgaggaaccc atccatgcca ccatggaccc ccagaggctg      900

ggcgtcctta tcactcctgt ccctgacgcc caggctgcca cccgg                      945


<210>  3422
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  3422
ttgagtatca ctactcctga agagatgatt gaaaaagcca aaggggaaac tgcctatctg       60

ccgtgcaaat ttacgcttag tcccgaagac cagggaccgc tggacatcga gtggctgata      120

tcaccagctg ataatcagaa ggtggatcaa gtgattattt tatattctgg agacaaaatt      180

tatgatgact actatccaga tctgaaaggc cgagtacatt ttacgagtaa tgatctcaaa      240

tctggtgatg catcaataaa tgtaacgaat ttacaactgt cagatattgg cacatatcag      300

tgcaaagtga aaaaagctcc tggtgttgca aataagaaga ttcatctggt agttcttgtt      360

aagccttcag gtgcgagatg ttacgttgat ggatctgaag aaattggaag tgactttaag      420

ataaaatgtg aaccaaaaga aggttcactt ccattacagt atgagtggca aaaattgtct      480

gactcacaga aaatgcccac ttcatggtta gcagaaatga cttcatctgt tatatctgta      540

aaaaatgcct cttctgagta ctctgggaca tacagctgta cagtcagaaa cagagtgggc      600

tctgatcagt gcctgttgcg tctaaacgtt gtccctcctt caaataaagc tgga            654


<210>  3423
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3423
gcgtccgtgg ccactgaact gcgctgccag tgcttgcaga ccctgcaggg aattcacccc       60

aagaacatcc aaagtgtgaa cgtgaagtcc cccggacccc actgcgccca aaccgaagtc      120

atagccacac tcaagaatgg gcggaaagct tgcctcaatc ctgcatcccc catagttaag      180

aaaatcatcg aaaagatgct gaacagtgac aaatccaac                             219


<210>  3424
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3424
gtacctctct ctagaactgt acgctgtacc tgcatcagca ttagtaatca acctgttaat       60

ccaaggtctt tagaaaaact tgaaattatt cctgcaagcc aattttgtcc acgtgttgag      120

atcattgcta caatgaaaaa gaagggtgag aagagatgtc tgaatccaga atcgaaggcc      180

atcaagaatt tactgaaagc agttagcaag gaaaggtcta aaagatctcc t               231


<210>  3425
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3425
ttccccatgt tcaaaagagg acgctgtctt tgcataggcc ctggggtaaa agcagtgaaa       60

gtggcagata ttgagaaagc ctccataatg tacccaagta acaactgtga caaaatagaa      120

gtgattatta ccctgaaaga aaataaagga caacgatgcc taaatcccaa atcgaagcaa      180

gcaaggctta taatcaaaaa agttgaaaga aagaatttt                             219


<210>  3426
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  3426
aagcccgtca gcctgagcta cagatgccca tgccgattct tcgaaagcca tgttgccaga       60

gccaacgtca agcatctcaa aattctcaac actccaaact gtgcccttca gattgtagcc      120

cggctgaaga acaacaacag acaagtgtgc attgacccga agctaaagtg gattcaggag      180

tacctggaga aagctttaaa caag                                             204


<210>  3427
<211>  261
<212>  DNA
<213>  Homo Sapiens

<400>  3427
gttctggagg tctattacac aagcttgagg tgtagatgtg tccaagagag ctcagtcttt       60

atccctagac gcttcattga tcgaattcaa atcttgcccc gtgggaatgg ttgtccaaga      120

aaagaaatca tagtctggaa gaagaacaag tcaattgtgt gtgtggaccc tcaagctgaa      180

tggatacaaa gaatgatgga agtattgaga aaaagaagtt cttcaactct accagttcca      240

gtgtttaaga gaaagattcc c                                                261


<210>  3428
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3428
tccaaatgca agtgctcccg gaagggaccc aagatccgct acagcgacgt gaagaagctg       60

gaaatgaagc caaagtaccc gcactgcgag gagaagatgg ttatcatcac caccaagagc      120

gtgtccaggt accgaggtca ggagcactgc ctgcacccca agctgcagag caccaagcgc      180

ttcatcaagt ggtacaacgc ctggaacgag aagcgcaggg tctacgaaga a               231


<210>  3429
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  3429
aacgagggca gcgtcactgg aagttgttat tgtggtaaaa gaatttcttc cgactccccg       60

ccatcggttc agttcatgaa tcgtctccgg aaacacctga gagcttacca tcggtgtcta      120

tactacacga ggttccagct cctttcctgg agcgtgtgtg gaggcaacaa ggacccatgg      180

gttcaggaat tgatgagctg tcttgatctc aaagaatgtg gacatgctta ctcggggatt      240

gtggcccacc agaagcattt acttcctacc agccccccaa tttctcaggc ctcagagggg      300

gcatcttcag atatccacac ccctgcccag atgctcctgt ccaccttgca gtccactcag      360

cgccccaccc tcccagtagg atcactgtcc tcggacaaag agctcactcg tcccaatgaa      420

accaccattc acactgcggg ccacagtctg gcagctgggc ctgaggctgg ggagaaccag      480

aagcagccgg aaaaaaatgc tggtcccaca gccaggacat cagccaca                   528


<210>  3430
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  3430
ttcatgacag tgtctgggct gccaaagaag cagtgcccct gtgatcattt caagggcaat       60

gtgaagaaaa caagacacca aaggcaccac agaaagccaa acaagcattc cagagcctgc      120

cagcaatttc tcaaacaatg tcagctaaga agctttgctc tgcctttg                   168


<210>  3431
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  3431
actgaactgc gctgccagtg cttgcagacc ctgcagggaa ttcacctcaa gaacatccaa       60

agtgtgaagg tgaagtcccc cggaccccac tgcgcccaaa ccgaagtcat agccacactc      120

aagaatgggc agaaagcttg tctcaacccc gcatcgccca tggttaagaa aatcatcgaa      180

aagatgctga aaaatggcaa atccaac                                          207


<210>  3432
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3432
gcgtccgtgg tcactgaact gcgctgccag tgcttgcaga cactgcaggg aattcacctc       60

aagaacatcc aaagtgtgaa tgtaaggtcc cccggacccc actgcgccca aaccgaagtc      120

atagccacac tcaagaatgg gaagaaagct tgtctcaacc ccgcatcccc catggttcag      180

aaaatcatcg aaaagatact gaacaagggg agcaccaac                             219


<210>  3433
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  3433
ttgagagagc tgcgttgcgt ttgtttacag accacgcaag gagttcatcc caaaatgatc       60

agtaatctgc aagtgttcgc cataggccca cagtgctcca aggtggaagt ggtagcctcc      120

ctgaagaacg ggaaggaaat ttgtcttgat ccagaagccc cttttctaaa gaaagtcatc      180

cagaaaattt tggacggtgg aaacaaggaa aac                                   213


<210>  3434
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3434
ggtcctgtct ctgctgtgct gacagagctg cgttgcactt gtttacgcgt tacgctgaga       60

gtaaacccca aaacgattgg taaactgcag gtgttccccg caggcccgca gtgctccaag      120

gtggaagtgg tagcctccct gaagaacggg aagcaagttt gtctggaccc ggaagcccct      180

tttctaaaga aagtcatcca gaaaattttg gacagtggaa acaaaaaaaa c               231


<210>  3435
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  3435
accccagtag tgagaaaggg tcgctgttcc tgcatcagca ccaaccaagg gactatccac       60

ctacaatcct tgaaagacct taaacaattt gccccaagcc cttcctgcga gaaaattgaa      120

atcattgcta cactgaagaa tggagttcaa acatgtctaa acccagattc agcagatgtg      180

aaggaactga ttaaaaagtg ggagaaacag gtcagccaaa agaaaaagca aaagaatggg      240

aaaaaacatc aaaaaaagaa agttctgaaa gttcgaaaat ctcaacgttc tcgtcaaaag      300

aagactaca                                                              309


<210>  3436
<211>  1872
<212>  DNA
<213>  Homo Sapiens

<400>  3436
cactggccca gtgaaccctc agaggctgtc agggactggg aaaaccagct tgaggcatcc       60

atgcactcag tgctctcaga cctccacgag gctgttccca cagtggttgg cattcctgat      120

ggcacggctg tcgtcgggcg ctcatttcga gtgaccattc caacagattt gattgcctcc      180

agtggagata tcatcaaggt atcagcggca gggaaggagg ctttgccatc ttggctgcac      240

tgggactcac agagccacac cctggagggc ctcccccttg acactgataa gggtgtgcat      300

tacatttcag tgagcgctac acggctgggg gccaacggga gccacatccc ccagacctcc      360

agtgtgttct ccatcgaggt ctaccctgaa gaccacagtg agctgcagtc ggtgaggaca      420

gcctccccag accctggtga ggtggtatca tctgcctgtg ctgcggatga acctgtgact      480

gttttgacgg tgattttgga tgccgacctc accaagatga ccccaaagca aaggattgac      540

ctcctgcaca ggatgcggag cttctcagaa gtagagcttc acaacatgaa attagtgccg      600

gtggtgaata acagactatt tgacatgtcg gccttcatgg ctggcccggg aaatgcaaaa      660

aaggtggtgg agaatggggc ccttctctcc tggaagctgg gctgctccct gaaccagaac      720

agtgtgcctg acattcatgg tgtagaggcc cctgccaggg agggcgcaat gtctgctcag      780

cttggctacc ctgtggtggg ttggcacatc gccaataaga agccccctct tcccaaacgc      840

gtccggaggc agatccatgc tacacccaca cctgtcactg ccattgggcc cccaaccacg      900

gctatccagg agcccccatc caggatcgtg ccaaccccca catctccagc cattgctcct      960

ccaacagaga ccatggctcc tccagtcagg gatcctgttc ctgggaaacc cacggtcacc     1020

atccggactc gaggcgccat tattcaaacc ccaaccctag gccccatcca gcctactcgg     1080

gtgtcagaag ctggcaccac agttcctggc cagattcgcc caacgatgac cattcctggc     1140

tatgtggagc ctactgcagt tgctacccct cccacaacca ccaccaagaa gccacgagta     1200

tccacaccaa aaccagcaac gccttcaact gactccacca ccaccacgac tcgcaggcca     1260

accaagaaac cacggacacc ccggccagtg ccccgggtca ccaccaaagt ttccatcacc     1320

agattggaaa ctgcctcacc gcctactcgt attcgcacca ccaccagtgg agtgccccgt     1380

ggcggagaac ccaaccagcg cccagagctc aagaaccata ttgacagggt agatgcctgg     1440

gttggcacct actttgaggt gaagatcccg tcagacactt tctatgacca tgaggacacc     1500

accactgaca agctgaagct gaccctgaaa ctgcgggagc agcagctggt gggcgagaag     1560

tcctgggtac agttcaacag caacagccag ctcatgtatg gccttcccga cagcagccac     1620

gtgggcaaac acgagtattt catgcatgcc acagacaagg ggggcctgtc ggctgtggat     1680

gccttcgaga tccacgtcca caggcgcccc caaggggata gggctcctgc aaggttcaag     1740

gccaagtttg tgggtgaccc ggcactggtg ttgaatgaca tccacaagaa gattgccttg     1800

gtaaagaaac tggccttcgc ctttggagac cgaaactgta gcaccatcac cctgcagaat     1860

atcacccggg gc                                                         1872


<210>  3437
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  3437
aggcctgaac cccagtctcc tcgacctcag tcctgggctg cagccaatca gacctgggct       60

ctgggcccag gggccctgcc cccactggtg ccagcttctg cccttgggag ctggaaggcc      120

ttcttgggcc tgcagaaagc caggcagctg gggatgggca ggctgcagcg tgggcaagac      180

gaggtggctg ctgtgactct gccgctgaac cctcaggaag tgatccaggg gatgtgtaag      240

gctgtgccct tcgttcaggt gttctcccgg cccggctgct cagccatacg cctccgaaat      300

catctgtgct ttggtcattg ctcctctctc tacatccctg gctcggaccc caccccacta      360

gtcctgtgca acagctgtat gcctgctcgc aagcgttggg cacccgtggt cctgtggtgt      420

ctcactggca gctcagcctc ccgtcgacgg gtgaagatat ccaccatgct gatcgagggg      480

tgtcactgca gcccaaaagc a                                                501


<210>  3438
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  3438
gatgaggctt ctgggatagg cccagaagtt cctgatgacc gcgacttcga gccctcccta       60

ggcccagtgt gccccttccg ctgtcaatgc catcttcgag tggtccagtg ttctgatttg      120

ggtctggaca aagtgccaaa ggatcttccc cctgacacaa ctctgctaga cctgcaaaac      180

aacaaaataa ccgaaatcaa agatggagac tttaagaacc tgaagaacct tcacgcattg      240

attcttgtca acaataaaat tagcaaagtt agtcctggag catttacacc tttggtgaag      300

ttggaacgac tttatctgtc caagaatcag ctgaaggaat tgccagaaaa aatgcccaaa      360

actcttcagg agctgcgtgc ccatgagaat gagatcacca aagtgcgaaa agttactttc      420

aatggactga accagatgat tgtcatagaa ctgggcacca atccgctgaa gagctcagga      480

attgaaaatg gggctttcca gggaatgaag aagctctcct acatccgcat tgctgatacc      540

aatatcacca gcattcctca aggtcttcct ccttccctta cggaattaca tcttgatggc      600

aacaaaatca gcagagttga tgcagctagc ctgaaaggac tgaataattt ggctaagttg      660

ggattgagtt tcaacagcat ctctgctgtt gacaatggct ctctggccaa cacgcctcat      720

ctgagggagc ttcacttgga caacaacaag cttaccagag tacctggtgg gctggcagag      780

cataagtaca tccaggttgt ctaccttcat aacaacaata tctctgtagt tggatcaagt      840

gacttctgcc cacctggaca caacaccaaa aaggcttctt attcgggtgt gagtcttttc      900

agcaacccgg tccagtactg ggagatacag ccatccacct tcagatgtgt ctacgtgcgc      960

tctgccattc aactcggaaa ctataag                                          987


<210>  3439
<211>  708
<212>  DNA
<213>  Homo Sapiens

<400>  3439
cgacacaatc tcaacaacgt gatcgcatcg ctgggctgca ccgtggagct gcagatcaac       60

aacacccgcg cagcttggcg catctccaca gcccccttac gggccatgtt caaggacctg      120

ctgagtagca aagaattgct gagagcagag actcggaaca tctccgccac ttttgaggac      180

ctggatgccc aggtgaatag tgagacgggc tacacgcctg aggataccat ggactcaggg      240

gagacagccc agggcaggga ggcccgccaa gccccagcct ccagactcca cctgtcgaca      300

cagaagatgt atgagctgaa gaccaagctg cgttgctcct atgtggtgaa ccaggccata      360

ctcagctgcc gtcgttggtt tgaccgcaag catgaacagt gcatgaagca catctgggtc      420

ccactcctca cccacctgct ctgcctgcct atgaagttca agttcttctg tggcattgcc      480

aaggtgatgg aggtttggtg ccgcaatcgc atcccagtgg aaggcaactt tgggcagacc      540

tacgactccc tcaaccagtc tattcgtggc ctggatgggg aattttcagc caatattgac      600

ttcaaggaag agaagcaggc tggggtgctg gggctcaaca caagctggga gcgcgtgagc      660

accgaggtgc gggactacgt gtaccgccag gaggcccggc tggagtgg                   708


<210>  3440
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  3440
aaaggtctcc tagatggtat gacttgcaac ctaagggcaa agagcttttc catacatttt       60

ccacttttga aaaaatatat tgaggcaatt cagtggattt atggccttgc cactccacta      120

agtgtatttg atgaccttgt ttcttggaac cagaccctgg cagtctctct tttcagtccc      180

agccatgtcc tggaggcaca gctaaatgac agcaaagggg aagtcctgag cgtcttgtac      240

cagatggcaa caaccacaga ggtgttgtcc tcc                                   273


<210>  3441
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  3441
gacatcccag aagtggttgt ttcccttgca tgggacgaaa gcttggctcc aaagcatcca       60

ggctcaagga aaaacatggc ctgctattgc agaataccag cgtgcattgc aggagaacgt      120

cgctatggaa cctgcatcta ccagggaaga ctctgggcat tctgctgc                   168


<210>  3442
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  3442
tccggggtat ttcaattgca gcttcaggag tttatcaacg aacgtggcgt gttagcatca       60

ggcaggcctt gtgaacccgg ctgccgtacc tttttcaggg tgtgtctgaa acactttcag      120

gccgtagtgt cacctgggcc atgtaccttt ggcacggtat ccacgccagt cctaggtacc      180

aattccttcg cagtacgtga cgactctagc ggcgggggtc gtaacccgct tcaacttcca      240

ttcaacttca catggcctgg gacgttctct ctaataatcg aggcatggca cgcacccggc      300

gatgatttgc gtccggaggc cctgccgccg gatgcactga tcagcaagat agccatacaa      360

ggtagtctgg ctgtcggtca aaactggtta ttagatgaac aaacgtcaac attgacaagg      420

ctgcgttaca gctacagagt aatctgctcc gacaattact acggcgacaa ttgctcacgt      480

ttatgtaaga agaggaatga ccactttggc cattacgttt gtcaaccaga cggtaattta      540

tcatgtcttc cgggctggac aggggagtat tgtcagcagc ccatctgctt atcaggatgc      600

catgagcaga atggttattg tagtaaacct gcggaatgct tgtgtcgtcc tggctggcag      660

ggcagattat gcaacgagtg cataccacat aacggctgcc gtcacggaac gtgcagtacc      720

ccatggcagt gtacatgcga cgagggttgg ggagggttat tctgtgatca ggaccttaat      780

tattgcaccc accactcacc ctgcaaaaac ggtgcgacgt gttccaactc cggtcaacgt      840

agctatactt gtacgtgtag accgggctac acgggtgtgg attgtgaatt agagctatca      900

gaatgcgact caaatccctg ccgtaatggt gggtcctgta aggatcagga ggatgggtac      960

cactgcttat gtccaccggg gtattacggt cttcactgcg aacatagcac cctgagctgt     1020

gctgatagtc cctgctttaa cggggggagt tgccgtgagc gtaatcaggg cgctaattat     1080

gcgtgtgagt gtcctccaaa ctttaccggc tctaactgtg agaaaaaggt ggacaggtgc     1140

acttctaacc cttgcgcgaa cggggggcag tgtctaaacc gtggaccctc caggatgtgc     1200

aggtgcaggc ctggatttac aggtacatac tgcgaactgc atgtgagtga ctgcgccagg     1260

aatccctgtg cccatggcgg cacctgtcac gatttagaaa acggactaat gtgtacgtgt     1320

cccgccggct tttctggtag gcgttgcgag gtacgtacta gtatagacgc ctgcgctagt     1380

tccccctgct ttaacagggc cacatgctat acggaccttt ctacggatac tttcgtatgt     1440

aattgcccgt atggttttgt tggcagcagg tgcgaatttc cagtgggtct tccaccctcc     1500


<210>  3443
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  3443
accgagccgc tgcggccaga gctgcggtgc aaccctgggc agtttgcgtg tcgcagcggc       60

accatccagt gcatccccct cccctggcag tgtgacggct gggcgacttg cgaggatgag      120

agcgacgaag ccaactgtcc agaagtgacc ggggaggtgc gtcctcatca tgggaaggag      180

gctgtggatc cgcggcaggg gcgggccaga ggaggcgacc cttcgcactt ccacgcggtg      240

aacgtggcgc agcccgttcg cttcagcagt ttcctaggga agtgcccgac agggtggcac      300

cactacgaag gcacggccag ctgctaccgg gtctacctga gcggggagaa ctactgggat      360

gccgcgcaga cctgccagcg cctgaatggc tctctcgcca ccttctccac tgaccaggag      420

ctgcgctttg tcctggccca ggaatgggac cagcccgagc ggagctttgg ttggaaggac      480

cagcgcaagt tgtgggttgg ctatcagtat gttatcactg gccggaaccg ctccttggaa      540

ggtcgctggg aggtggcatt caaaggctct tcagaggtgt tcctgccccc agaccccatc      600

tttgcctcgg ccatgtctga gaacgacaac gtgttctgtg cccagcttca gtgcttccat      660

ttccccaccc tgcggcacca cgacctccac agctggcacg ccgagagctg ctacgagaag      720

tcttcatttc tgtgtaaaag aagtcaaaca tgtgttgaca tcaaggacaa cgtggtggat      780

gaagggttct acttcacccc taagggggac gacccatgcc tgagctgcac ctgccatgga      840

ggggagcctg agatgtgtgt ggctgctctc tgtgagaggc cccagggctg ccaacagtac      900

cgcaaggacc ccaaagagtg ctgcaagttc atgtgtctgg acccagatgg caacagtctg      960

tttgactcca tggccagcgg gatgcgc                                          987


<210>  3444
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  3444
gatctgaaag tagagatgat ggcagggggg actcagatca cacccctgaa tgacaatgtc       60

accatattct gcaatatctt ttattcccaa cccctcaaca tcacgtctat gggtatcacc      120

tggttttgga agagtctgac gtttgacaaa gaagtcaaag tctttgaatt ttttggagat      180

caccaagagg cattccgacc tggagccatt gtgtctccat ggaggctgaa gagtggggac      240

gcctcactgc ggctgcctgg aatccagctg gaggaagcag gagagtaccg atgtgaggtg      300

gtggtcaccc ctctgaaggc acagggaaca gtccagcttg aagttgtggc ttccccagcc      360

agcagattgt tgctggatca agtgggcatg aaagagaatg aagacaaata tatgtgtgag      420

tcaagtgggt tctacccaga ggctattaat ataacatggg agaagcagac ccagaagttt      480

ccccatccca tagagatttc tgaggatgtc atcactggtc ccaccatcaa gaatatggat      540

ggcacattta atgtcactag ctgcttgaag ctgaactcct ctcaggaaga ccctgggact      600

gtctaccagt gtgtggtacg gcatgcgtcc ttgcataccc ccttgaggag caactttacc      660

ctgactgctg ctcggcacag tctttctgaa actgagaaga cagataattt ttcc            714


<210>  3445
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  3445
gctgaatgct tcccggcctg caacccccaa aatggattct gcgaggatga caatgtttgc       60

aggtgccagc ctggctggca gggtcccctt tgtgaccagt gcgtgacctc tcccggctgc      120

cttcacggac tctgtggaga acccgggcag tgcatttgca ccgacggctg ggacggggag      180

ctctgtgata gagatgttcg ggcctgctcc tcggccccct gtgccaacaa cgggacctgc      240

gtgagcctgg acgatggcct ctatgaatgc tcctgtgccc ccgggtactc gggaaaggac      300

tgccagaaaa aggacgggcc ctgtgtgatc aacggctccc cctgccagca cggaggcacc      360

tgcgtggatg atgagggccg ggcctcccat gcctcctgcc tgtgcccccc tggcttctca      420

ggcaatttct gcgagatcgt ggccaacagc tgcaccccca acccatgcga gaacgacggc      480

gtctgcactg acatcggggg cgacttccgc tgccggtgcc cagccggctt catcgacaag      540

acctgcagcc gcccggtgac caactgcgcc agcagcccgt gccagaacgg gggcacctgc      600

ctgcagcaca cccaggtgag ctacgagtgt ctgtgcaagc ccgagttcac aggtctcacc      660

tgtgtcaaga agcgcgcgct gagcccccag caggtcaccc gtctgcccaa cggctatggg      720

ctggcctacc gcctgacccc tggggtgcac gagctgccgg tgcagcagcc ggagcaccgc      780

atcctgaagg tgtccatgaa agagctcaac aagaaaaccc ctctcctcac cgagggccag      840


<210>  3446
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  3446
gatgactgca gctcccactg tgacctggcc cacggctgct gtgcacctga cggctcctgc       60

aggtgtgacc cgggctggga ggggctgcac tgtgagcgct gtgtgaggat gcctggctgc      120

cagcacggta cctgccacca gccatggcag tgcatctgcc acagtggctg ggcaggcaag      180

ttctgtgaca aagatgaaca tatctgtacc acgcagtccc cctgccagaa tggaggccag      240

tgcatgtatg acgggggcgg tgagtaccat tgtgtgtgct taccaggctt ccatgggcgt      300

gactgcgagc gcaaggctgg accctgtgaa caggcaggct ccccatgccg caatggcggg      360

cagtgccagg acgaccaggg ctttgctctc aacttcacgt gccgctgctt ggtgggcttt      420

gtgggtgccc gctgtgaggt aaatgtggat gactgcctga tgcggccttg tgctaacggt      480

gccacctgcc ttgacggcat aaaccgcttc tcctgcctct gtcctgaggg ctttgctgga      540

cgcttctgca ccatcaacct ggatgactgt gccagccgcc catgccagag aggggcccgc      600

tgtcgggacc gtgtccacga cttcgactgc ctctgcccca gtggctatgg tggcaagacc      660

tgtgagcttg tcttacctgt cccagacccc ccaaccacag tggacacccc tctagggccc      720

acctcagctg tagtggtacc tgccacgggg ccagcccccc acagcgcagg ggctggtctg      780

ctgcggatct cagtgaagga ggtggtgcgg aggcaagagg ctgggctagg tgagcctagc      840


<210>  3447
<211>  1584
<212>  DNA
<213>  Homo Sapiens

<400>  3447
caggtctgga gctctggggt gttcgaactg aagctgcagg agttcgtcaa caagaagggg       60

ctgctgggga accgcaactg ctgccgcggg ggcgcggggc caccgccgtg cgcctgccgg      120

accttcttcc gcgtgtgcct caagcactac caggccagcg tgtcccccga gccgccctgc      180

acctacggca gcgccgtcac ccccgtgctg ggcgtcgact ccttcagtct gcccgacggc      240

gggggcgccg actccgcgtt cagcaacccc atccgcttcc ccttcggctt cacctggccg      300

ggcaccttct ctctgattat tgaagctctc cacacagatt ctcctgatga cctcgcaaca      360

gaaaacccag aaagactcat cagccgcctg gccacccaga ggcacctgac ggtgggcgag      420

gagtggtccc aggacctgca cagcagcggc cgcacggacc tcaagtactc ctaccgcttc      480

gtgtgtgacg aacactacta cggagagggc tgctccgttt tctgccgtcc ccgggacgat      540

gccttcggcc acttcacctg tggggagcgt ggggagaaag tgtgcaaccc tggctggaaa      600

gggccctact gcacagagcc gatctgcctg cctggatgtg atgagcagca tggattttgt      660

gacaaaccag gggaatgcaa gtgcagagtg ggctggcagg gccggtactg tgacgagtgt      720

atccgctatc caggctgtct ccatggcacc tgccagcagc cctggcagtg caactgccag      780

gaaggctggg ggggcctttt ctgcaaccag gacctgaact actgcacaca ccataagccc      840

tgcaagaatg gagccacctg caccaacacg ggccagggga gctacacttg ctcttgccgg      900

cctgggtaca caggtgccac ctgcgagctg gggattgacg agtgtgaccc cagcccttgt      960

aagaacggag ggagctgcac ggatctcgag aacagctact cctgtacctg cccacccggc     1020

ttctacggca aaatctgtga attgagtgcc atgacctgtg cggacggccc ttgctttaac     1080

gggggtcggt gctcagacag ccccgatgga gggtacagct gccgctgccc cgtgggctac     1140

tccggcttca actgtgagaa gaaaattgac tactgcagct cttcaccctg ttctaatggt     1200

gccaagtgtg tggacctcgg tgatgcctac ctgtgccgct gccaggccgg cttctcgggg     1260

aggcactgtg acgacaacgt ggacgactgc gcctcctccc cgtgcgccaa cgggggcacc     1320

tgccgggatg gcgtgaacga cttctcctgc acctgcccgc ctggctacac gggcaggaac     1380

tgcagtgccc ccgtcagcag gtgcgagcac gcaccctgcc acaatggggc cacctgccac     1440

gagaggggcc accgctatgt gtgcgagtgt gcccgaggct acgggggtcc caactgccag     1500

ttcctgctcc ccgagctgcc cccgggccca gcggtggtgg acctcactga gaagctagag     1560

ggccagggcg ggccattccc ctgg                                            1584


<210>  3448
<211>  1398
<212>  DNA
<213>  Homo Sapiens

<400>  3448
gctggcgtct tcgagctgca gatccactct ttcgggccgg gtccaggccc tggggccccg       60

cggtccccct gcagcgcccg gctcccctgc cgcctcttct tcagagtctg cctgaagcct      120

gggctctcag aggaggccgc cgagtccccg tgcgccctgg gcgcggcgct gagtgcgcgc      180

ggaccggtct acaccgagca gcccggagcg cccgcgcctg atctcccact gcccgacggc      240

ctcttgcagg tgcccttccg ggacgcctgg cctggcacct tctctttcat catcgaaacc      300

tggagagagg agttaggaga ccagattgga gggcccgcct ggagcctgct ggcgcgcgtg      360

gctggcaggc ggcgcttggc agccggaggc ccgtgggccc gggacattca gcgcgcaggc      420

gcctgggagc tgcgcttctc gtaccgcgcg cgctgcgagc cgcctgccgt cgggaccgcg      480

tgcacgcgcc tctgccgtcc gcgcagcgcc ccctcgcggt gcggtccggg actgcgcccc      540

tgcgcaccgc tcgaggacga atgtgaggcg ccgctggtgt gccgagcagg ctgcagccct      600

gagcatggct tctgtgaaca gcccggtgaa tgccgatgcc tagagggctg gactggaccc      660

ctctgcacgg tccctgtctc caccagcagc tgcctcagcc ccaggggccc gtcctctgct      720

accaccggat gccttgtccc tgggcctggg ccctgtgacg ggaacccgtg tgccaatgga      780

ggcagctgta gtgagacacc caggtccttt gaatgcacct gcccgcgtgg gttctacggg      840

ctgcggtgtg aggtgagcgg ggtgacatgt gcagatggac cctgcttcaa cggcggcttg      900

tgtgtcgggg gtgcagaccc tgactctgcc tacatctgcc actgcccacc cggtttccaa      960

ggctccaact gtgagaagag ggtggaccgg tgcagcctgc agccatgccg caatggcgga     1020

ctctgcctgg acctgggcca cgccctgcgc tgccgctgcc gcgccggctt cgcgggtcct     1080

cgctgcgagc acgacctgga cgactgcgcg ggccgcgcct gcgctaacgg cggcacgtgt     1140

gtggagggcg gcggcgcgca ccgctgctcc tgcgcgctgg gcttcggcgg ccgcgactgc     1200

cgcgagcgcg cggacccgtg cgccgcgcgc ccctgtgctc acggcggccg ctgctacgcc     1260

cacttctccg gcctcgtctg cgcttgcgct cccggctaca tgggagcgcg gtgtgagttc     1320

ccagtgcacc ccgacggcgc aagcgccttg cccgcggccc cgccgggcct caggcccggg     1380

gaccctcagc gctacctt                                                   1398


<210>  3449
<211>  1509
<212>  DNA
<213>  Homo Sapiens

<400>  3449
tccggcgtct tccagctgca gctgcaggag ttcatcaacg agcgcggcgt actggccagt       60

gggcggcctt gcgagcccgg ctgccggact ttcttccgcg tctgccttaa gcacttccag      120

gcggtcgtct cgcccggacc ctgcaccttc gggaccgtct ccacgccggt attgggcacc      180

aactccttcg ctgtccggga cgacagtagc ggcggggggc gcaaccctct ccaactgccc      240

ttcaatttca cctggccggg taccttctcg ctcatcatcg aagcttggca cgcgccagga      300

gacgacctgc ggccagaggc cttgccacca gatgcactca tcagcaagat cgccatccag      360

ggctccctag ctgtgggtca gaactggtta ttggatgagc aaaccagcac cctcacaagg      420

ctgcgctact cttaccgggt catctgcagt gacaactact atggagacaa ctgctcccgc      480

ctgtgcaaga agcgcaatga ccacttcggc cactatgtgt gccagccaga tggcaacttg      540

tcctgcctgc ccggttggac tggggaatat tgccaacagc ctatctgtct ttcgggctgt      600

catgaacaga atggctactg cagcaagcca gcagagtgcc tctgccgccc aggctggcag      660

ggccggctgt gtaacgaatg catcccccac aatggctgtc gccacggcac ctgcagcact      720

ccctggcaat gtacttgtga tgagggctgg ggaggcctgt tttgtgacca agatctcaac      780

tactgcaccc accactcccc atgcaagaat ggggcaacgt gctccaacag tgggcagcga      840

agctacacct gcacctgtcg cccaggctac actggtgtgg actgtgagct ggagctcagc      900

gagtgtgaca gcaacccctg tcgcaatgga ggcagctgta aggaccagga ggatggctac      960

cactgcctgt gtcctccggg ctactatggc ctgcattgtg aacacagcac cttgagctgc     1020

gccgactccc cctgcttcaa tgggggctcc tgccgggagc gcaaccaggg ggccaactat     1080

gcttgtgaat gtccccccaa cttcaccggc tccaactgcg agaagaaagt ggacaggtgc     1140

accagcaacc cctgtgccaa cgggggacag tgcctgaacc gaggtccaag ccgcatgtgc     1200

cgctgccgtc ctggattcac gggcacctac tgtgaactcc acgtcagcga ctgtgcccgt     1260

aacccttgcg cccacggtgg cacttgccat gacctggaga atgggctcat gtgcacctgc     1320

cctgccggct tctctggccg acgctgtgag gtgcggacat ccatcgatgc ctgtgcctcg     1380

agtccctgct tcaacagggc cacctgctac accgacctct ccacagacac ctttgtgtgc     1440

aactgccctt atggctttgt gggcagccgc tgcgagttcc ccgtgggctt gccgcccagc     1500

ttcccctgg                                                             1509


<210>  3450
<211>  1818
<212>  DNA
<213>  Homo Sapiens

<400>  3450
aacccggtgc ccgccgcgcc cttgtctgcg cccgggccgt gcgccgcgca gccctgccgg       60

aatgggggtg tgtgcacctc gcgccctgag ccggacccgc agcacccggc ccccgccggc      120

gagcctggct acagctgcac ctgccccgcc gggatctccg gcgccaactg ccagcttgtt      180

gcagatcctt gtgccagcaa cccttgtcac catggcaact gcagcagcag cagcagcagc      240

agcagcgatg gctacctctg catttgcaat gaaggctatg aaggtcccaa ctgtgaacag      300

gcacttccca gtctcccagc cactggctgg accgaatcca tggcaccccg acagcttcag      360

cctgttcctg ctactcagga gcctgacaaa atcctgcctc gctctcaggc aacggtgaca      420

ctgcctacct ggcagccgaa aacagggcag aaagttgtag aaatgaaatg ggatcaagtg      480

gaggtgatcc cagatattgc ctgtgggaat gccagttcta acagctctgc gggtggccgc      540

ctggtatcct ttgaagtgcc acagaacacc tcagtcaaga ttcggcaaga tgccactgcc      600

tcactgattt tgctctggaa ggtcacggcc acaggattcc aacagtgctc cctcatagat      660

ggacgaagtg tgacccccct tcaggcttca gggggactgg tcctcctgga ggagatgctc      720

gccttgggga ataatcactt tattggtttt gtgaatgatt ctgtgactaa gtctattgtg      780

gctttgcgct taactctggt ggtgaaggtc agcacctgtg tgccggggga gagtcacgca      840

aatgacttgg agtgttcagg aaaaggaaaa tgcaccacga agccgtcaga ggcaactttt      900

tcctgtacct gtgaggagca gtacgtgggt actttctgtg aagaatacga tgcttgccag      960

aggaaacctt gccaaaacaa cgcgagctgt attgatgcaa atgaaaagca agatgggagc     1020

aatttcacct gtgtttgcct tcctggttat actggagagc tttgccagtc caagattgat     1080

tactgcatcc tagacccatg cagaaatgga gcaacatgca tttccagtct cagtggattc     1140

acctgccagt gtccagaagg atacttcgga tctgcttgtg aagaaaaggt ggacctctgc     1200

gcctcgtctc cgtgccagaa caacggcacc tgctatgtgg acggggtaca ctttacctgc     1260

aactgcagcc cgggcttcac agggccgacc tgtgcccagc ttattgactt ctgtgccctc     1320

agcccctgtg ctcatggcac gtgccgcagc gtgggcacca gctacaaatg cctctgtgat     1380

ccaggttacc atggcctcta ctgtgaggag gaatataatg agtgcctctc cgctccatgc     1440

ctgaatgcag ccacctgcag ggacctcgtt aatggctatg agtgtgtgtg cctggcagaa     1500

tacaaaggaa cacactgtga attgtacaag gatccctgcg ctaacgtcag ctgtctgaac     1560

ggagccacct gtgacagcga cggcctgaat ggcacgtgca tctgtgcacc cgggtttaca     1620

ggtgaagagt gcgacattga cataaatgaa tgtgacagta acccctgcca ccatggtggg     1680

agctgcctgg accagcccaa tggttataac tgccactgcc cgcatggttg ggtgggagca     1740

aactgtgaga tccacctcca atggaagtcc gggcacatgg cggagagcct caccaacatg     1800

ccacggcact ccctctac                                                   1818


<210>  3451
<211>  1677
<212>  DNA
<213>  Homo Sapiens

<400>  3451
agatgggctc caattccttg ttcgatgcta gaaaactcct tgggtccttt tccacttttc       60

cttcaacagg ttcaatctga cacggcccaa aactatacca tatactattc cataagaggt      120

cctggagttg accaagaacc tcggaattta ttttatgtgg agagagacac tggaaacttg      180

tattgtactc gtcctgtaga tcgtgagcag tatgaatctt ttgagataat tgcctttgca      240

acaactccag atgggtatac tccagaactt ccactgcccc taataatcaa aatagaggat      300

gaaaatgata actacccaat ttttacagaa gaaacttata cttttacaat ttttgaaaat      360

tgcagagtgg gcactactgt gggacaagtg tgtgctactg acaaagatga gcctgacacg      420

atgcacacac gcctgaagta ctccatcatt gggcaggtgc caccatcacc caccctattt      480

tctatgcatc caactacagg cgtgatcacc acaacatcat ctcagctaga cagagagtta      540

attgacaagt accagttgaa aataaaagta caagacatgg atggtcagta ttttggtcta      600

cagacaactt caacttgtat cattaacatt gatgatgtaa atgaccactt gccaacattt      660

actcgtactt cttatgtgac atcagtggaa gaaaatacag ttgatgtgga aatcttacga      720

gttactgttg aggataagga cttagtgaat actgctaact ggagagctaa ttataccatt      780

ttaaagggca atgaaaatgg caattttaaa attgtaacag atgccaaaac caatgaagga      840

gttctttgtg tagttaagcc tttgaattat gaagaaaagc aacagatgat cttgcaaatt      900

ggtgtagtta atgaagctcc attttccaga gaggctagtc caagatcagc catgagcaca      960

gcaacagtta ctgttaatgt agaagatcag gatgagggcc ctgagtgtaa ccctccaata     1020

cagactgttc gcatgaaaga aaatgcagaa gtgggaacaa caagcaatgg atataaagca     1080

tatgacccag aaacaagaag tagcagtggc ataaggtata agaaattaac tgatccaaca     1140

gggtgggtca ccattgatga aaatacagga tcaatcaaag ttttcagaag cctggataga     1200

gaggcagaga ccatcaaaaa tggcatatat aatattacag tccttgcatc agaccaagga     1260

gggagaacat gtacggggac actgggcatt atacttcaag acgtgaatga taacagccca     1320

ttcataccta aaaagacagt gatcatctgc aaacccacca tgtcatctgc ggagattgtt     1380

gcggttgatc ctgatgagcc tatccatggc ccaccctttg actttagtct ggagagttct     1440

acttcagaag tacagagaat gtggagactg aaagcaatta atgatacagc agcacgtctt     1500

tcctatcaga atgatcctcc atttggctca tatgtagtac ctataacagt gagagataga     1560

cttggcatgt ctagtgtcac ttcattggat gttacactgt gtgactgcat taccgaaaat     1620

gactgcacac atcgtgtaga tccaaggatt ggcggtggag gagtacaact tggaaag        1677


<210>  3452
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  3452
agatgggcac ctataccgtg ttctatgcag gagaattctt tgggcccctt cccgttattt       60

ctacagcaag tggagagcga cgcagctcaa aactatactg tcttctactc tatatctggt      120

agaggagtcg acaaggagcc gcttaatttg ttctatattg agagagacac tggcaaccta      180

ttctgcactc gtccagtaga tcgtgaagag tatgatgtat ttgacttgat agcatacgct      240

tctactgctg acggatattc tgcagattta cccctaccgc taccaataag ggtcgaggat      300

gagaatgata atcacccagt attcactgaa gctatctaca actttgaggt cttggaaagt      360

tcccgtcccg gtacaacggt aggtgtggtt tgcgcgacag acagggatga gccggataca      420

atgcatactc gtttgaagta ctcaatctta caacaaacgc cacgtagccc tggtctgttc      480

tccgtccacc catccactgg agtgattaca acggtctctc attacttaga ccgtgaagta      540

gtggataaat acagcctaat tatgaaggtc caggacatgg atggccagtt ttttggtctg      600

ataggtactt ccacatgcat tatcactgta acagattcta atgacaatgc tcctactttt      660

agacagaacg cctacgaagc attcgtcgaa gagaatgcct ttaatgtgga aatcttgcgt      720

atacctattg aagataaaga cctaataaac acagcgaact ggcgtgtcaa ttttacgatt      780

ttaaaaggta acgagaacgg gcactttaag atctcaacag ataaggagac gaacgagggc      840

gtattgtcag tggtgaaacc tctaaactac gaggagaacc gtcaggtgaa tttagagatt      900

ggagtgaata atgaggctcc cttcgcccgt gacataccga gagtaacagc tttaaacagg      960

gcattagtca ccgttcatgt aagggacctt gacgagggcc ctgaatgcac gccggcagcg     1020

cagtacgtga ggattaaaga aaacttggca gtggggtcaa aaatcaatgg ctataaagcc     1080

tacgatccag agaatcgtaa cggcaacggg ttaaggtaca aaaagctaca tgaccccaag     1140

ggttggatta caatcgacga aatttccggt tctataatta cgtcaaaaat cttggataga     1200

gaggtcgaga ctccgaaaaa cgaactttat aacatcaccg tgctagccat cgacaaggat     1260

gacaggtctt gcacgggcac tttggcggtc aacattgaag atgtgaacga taaccctcct     1320

gagattcttc aagaatatgt ggtcatatgc aagccaaaaa tgggctatac agacatattg     1380

gcagtggatc ctgatgaacc ggtccacggg gccccgtttt atttttcact tccgaatacc     1440

agccccgaga ttagccgttt gtggagtcta acaaaagtaa atgatactgc ggcacgtctg     1500

tcctaccaaa agaacgccgg cttccaggaa tacacaatcc cgataaccgt caaagatagg     1560

gcagggcaag cagccaccaa attattaaga gtaaatttat gtgaatgtac tcatcctaca     1620

caatgtagag ccacgtctag gtccacggga gtgatattgg gtaag                     1665


<210>  3453
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  3453
gcctggatca ccgcccccgt ggctcttcgg gagggagagg atctgtccaa gaagaatcca       60

attgccaaga tacattctga tcttgcagaa gaaagaggac tcaaaattac ttacaaatac      120

actggaaaag ggattacaga gccacctttt ggtatatttg tctttaacaa agatactgga      180

gaactgaatg ttaccagcat tcttgatcga gaagaaacac cattttttct gctaacaggt      240

tacgctttgg atgcaagagg aaacaatgta gagaaaccct tagagctacg cattaaggtt      300

cttgatatca atgacaacga accagtgttc acacaggatg tctttgttgg gtctgttgaa      360

gagttgagtg cagcacatac tcttgtgatg aaaatcaatg caacagatgc agatgagccc      420

aataccctga attcgaaaat ttcctataga atcgtatctc tggagcctgc ttatcctcca      480

gtgttctacc taaataaaga tacaggagag atttatacaa ccagtgttac cttggacaga      540

gaggaacaca gcagctacac tttgacagta gaagcaagag atggcaatgg agaagttaca      600

gacaaacctg taaaacaagc tcaagttcag attcgtattt tggatgtcaa tgacaatata      660

cctgtagtag aaaataaagt gcttgaaggg atggttgaag aaaatcaagt caatgtagaa      720

gttacgcgca taaaagtgtt cgatgcagat gaaataggtt ctgataattg gctggcaaat      780

tttacatttg catcaggaaa tgaaggaggt tatttccaca tagaaacaga tgctcaaact      840

aacgaaggaa ttgtgaccct tattaaggaa gtagattatg aagaaatgaa gaatcttgac      900

ttcagtgtta ttgtcgctaa taaagcagct tttcacaagt cgattaggag taaatacaag      960

cctacaccca ttcccatcaa ggtcaaagtg aaaaatgtga aagaaggcat tcattttaaa     1020

agcagcgtca tctcaattta tgttagcgag agcatggata gatcaagcaa aggccaaata     1080

attggaaatt ttcaagcttt tgatgaggac actggactac cagcccatgc aagatatgta     1140

aaattagaag atagagataa ttggatctct gtggattctg tcacatctga aattaaactt     1200

gcaaaacttc ctgattttga atctagatat gttcaaaatg gcacatacac tgtaaagatt     1260

gtggccatat cagaagatta tcctagaaaa accatcactg gcacagtcct tatcaatgtt     1320

gaagacatca acgacaactg tcccacactg atagagcctg tgcagacaat ctgtcacgat     1380

gcagagtatg tgaatgttac tgcagaggac ctggatggac acccaaacag tggccctttc     1440

agtttctccg tcattgacaa accacctggc atggcagaaa aatggaaaat agcacgccaa     1500

gaaagtacca gtgtgctgct gcaacaaagt gagaaaaagc ttgggagaag tgaaattcag     1560

ttcctgattt cagacaatca gggttttagt tgtcctgaaa agcaggtcct tacactcaca     1620

gtttgtgagt gtctgcatgg cagcggctgc agggaagcac agcatgactc ctatgtgggc     1680


<210>  3454
<211>  1698
<212>  DNA
<213>  Homo Sapiens

<400>  3454
gagtgggtta agtttgctaa gccgtgcaga gagggtgagg acaatagcaa gcgtaacccc       60

atcgcgaaga tcaccagcga ttaccaagct actcaaaaaa tcacgtacag aatttctggc      120

gtaggcattg accaacctcc ctttggaatc tttgttgtcg ataaaaacac cggtgatatt      180

aacatcaccg cgattgtaga tcgtgaggaa acgcccagtt ttctgattac gtgtcgtgca      240

ttaaacgccc aagggctgga cgtagagaaa ccattgattc tgacggtgaa gattctagac      300

attaacgata atccgcccgt cttttcccaa cagatattta tgggtgagat tgaagagaat      360

agcgcctcaa acagccttgt catgattttg aatgccaccg atgctgatga acctaatcat      420

cttaactcta aaattgcctt caaaatcgtg tcccaagaac ctgcgggcac ccccatgttt      480

ttactaagca ggaacacagg ggaagtacgt accctgacga actccttaga tcgtgagcaa      540

gcgtcatctt ataggctggt cgtttccggc gcggacaaag atggggaagg ccttagtacg      600

cagtgcgagt gtaatataaa ggtaaaagac gttaacgaca atttcccaat gttccgtgac      660

tctcagtact ctgcgcgtat cgaggagaat atactttctt ctgaactgct tagattccag      720

gtcaccgatc tggacgagga atacaccgac aactggctgg ctgtgtactt tttcactagt      780

ggcaacgagg ggaattggtt cgagatacag acagatcccc gtactaatga gggcatattg      840

aaggttgtta aggcattaga ctacgaacag ctacaaagcg tcaaacttag tattgcggtt      900

aaaaacaaag ctgagttcca ccaaagcgtc attagtagat atagagtaca atctacaccg      960

gtaacgatac aagttattaa tgttcgtgaa gggatagcgt ttcgtccagc ctctaaaacc     1020

ttcacggttc agaaagggat tagttcaaaa aaactagtgg actacatttt gggtacgtat     1080

caagcaattg atgaggacac gaacaaagcg gcgtcaaacg tgaaatacgt gatggggaga     1140

aatgacgggg gatatttaat gatcgacagt aagaccgctg agattaaatt cgtaaaaaac     1200

atgaataggg attccacgtt cattgtgaac aaaaccataa cggctgaggt actggctata     1260

gatgaatata ccgggaaaac ttctaccggt actgtctatg tcagggttcc agatttcaat     1320

gacaactgtc ccacagcagt tctagagaaa gacgccgtct gttcaagtag cccgtccgtt     1380

gtggtatccg cccgtactct taataatcgt tacactggtc cgtacacctt tgcgttggag     1440

gatcagccag ttaaactacc ggctgtgtgg tcaattacga cgttaaatgc tacaagtgca     1500

cttttgagag cgcaagaaca aatacctccc ggcgtttacc acatctcatt agtcttaact     1560

gattcccaaa acaaccgttg tgaaatgcct aggagcttga cgttggaagt atgtcagtgt     1620

gataaccgtg gaatttgtgg tacttcttat ccgacgactt cccctggtac gagatatggc     1680

agaccacaca gcggtagg                                                   1698


<210>  3455
<211>  1746
<212>  DNA
<213>  Homo Sapiens

<400>  3455
gagtggatca agtttgccgc agcctgtcga gaaggagagg acaactcgaa gaggaacccc       60

attgccaaaa ttcgatcaga ctgcgaatcg aaccagaaga taacataccg gatttctgga      120

gtagggattg atcgaccacc atatggggta ttcaccatta atcctcgcac tggggaaatt      180

aacatcactt cagtggtaga cagagaaata actccacttt tcttgatcta ttgccgggct      240

ctgaattcac ggggtgaaga tttagaaagg cctcttgagc ttagagtcaa agttatggac      300

ataaatgata acgctccagt cttttcgcaa agtgtataca cagccagcat tgaagaaaat      360

agtgatgcca atacattggt agtaaagtta tgtgccacag atgcagatga agaaaatcat      420

ctgaattcta aaattgccta caagatcgtc tctcaggagc catcaggtgc acccatgttc      480

attctgaata ggtacactgg agaagtctgc accatgtcca gtttcttgga cagagagcaa      540

cacagtatgt acaacctggt tgtgagaggc tcagatcggg atggagctgc agatggactg      600

tcttctgagt gtgactgtag aatcaaggtt ttagacgtca acgataattt ccccacctta      660

gagaaaactt catactcagc cagtattgaa gagaattgtt taagttcgga actgatacga      720

ttacaagcaa ttgatcttga tgaagaaggc actgataact ggttggctca atatttaatt      780

ctctctggaa atgatgggaa ttggttcgat attcaaacag atccacaaac caatgaaggc      840

attttgaaag ttgtcaagat gctggattat gaacaagcac ctaacattca gcttagtatc      900

ggagttaaaa accaagctga ttttcactac tccgttgctt ctcaattcca aatgcaccca      960

acccctgtga gaattcaagt tgttgatgtg agagaaggac ctgcatttca tccaagtact     1020

atggctttta gtgtgcggga aggaataaaa ggaagttcct tattgaatta tgtgcttggc     1080

acatatacag ccatagattt ggacacagga aaccctgcaa cagatgtcag atatatcata     1140

gggcatgatg caggcagctg gttaaaaatt gattcaagaa ctggtgagat acaattttct     1200

agagaatttg ataagaagtc aaaatatatt atcaatggga tatacacagc agagatcctg     1260

gctatagatg atggctctgg aaaaacagct acaggaacca tatgtattga ggttcctgat     1320

atcaatgatt attgtccaaa catttttcct gaaagaagaa ccatctgcat tgactctcca     1380

tcagtcctta tctctgttaa tgaacattct tatgggtctc cgtttacttt ctgtgttgtt     1440

gatgagccac caggaatagc tgacatgtgg gatgtcagat caacaaatgc tacctcggca     1500

atccttacgg ctaagcaggt tttatctcca ggattttatg aaatcccaat cctggtgaag     1560

gacagctata acagagcatg tgaattggca caaatggtgc agttatatgc ctgtgattgc     1620

gatgacaacc acatgtgcct ggactctggt gccgcgggca tctacacaga ggacataact     1680

ggtgacacgt atgggcctgt cactgaagac caagctggag tttcaaatgt tggtcttgga     1740

ccagca                                                                1746


<210>  3456
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  3456
aggaaagggc ccccagcagc tctgacactg ccccgggtgc aatgccgagc ctctcggtac       60

ccgatcgccg tggattgctc ctggaccctg ccgcctgctc caaactccac cagccccgtg      120

tccttcattg ccacgtacag gctcggcatg gctgcccggg gccacagctg gccctgcctg      180

cagcagacgc caacgtccac cagctgcacc atcacggatg tccagctgtt ctccatggct      240

ccctacgtgc tcaatgtcac cgccgtccac ccctggggct ccagcagcag cttcgtgcct      300

ttcataacag agcacatcat caagcccgac cctccagaag gcgtgcgcct aagccccctc      360

gctgagcgcc agctacaggt gcagtgggag cctcccgggt cctggccctt cccagagatc      420

ttctcactga agtactggat ccgttacaag cgtcagggag ctgcgcgctt ccaccgggtg      480

gggcccattg aagccacgtc cttcatcctc agggctgtgc ggccccgagc caggtactac      540

gtccaagtgg cggctcagga cctcacagac tacggggaac tgagtgactg gagtctcccc      600

gccactgcca caatgagcct gggcaag                                          627


<210>  3457
<211>  1869
<212>  DNA
<213>  Homo Sapiens

<400>  3457
aaaaatgaag aaattcctag gaagcaaagg aggaagatct accacagaag gttgaggaaa       60

agttcaacct cacacaagca cagatcaaac agacagcttg gaattccgca aacaacagtt      120

tttacaccag tagcaagact tcctattgtt aactttgatt atagcatgga ggaaaagttt      180

gaatcctttt caagttttcc tggagtagaa tcaagttata atgtgttacc aggaaagaag      240

ggacactgtt tggtaaaggg cataaccatg tacaacaaag ctgtgtggtc gcctgagccc      300

tgcactacct gcctctgctc agatggaaga gttctttgtg atgaaaccat gtgccatccc      360

cagaggtgcc cccaaacagt tatacctgaa ggggaatgct gcccggtctg ctccgctact      420

gaacaaagag aacctaccaa tttacttcat aagcaactgc cacctcctca ggtgggaatg      480

gaccgaatag taagaaaaga agcacttcaa tctgaggagg atgaagaagt gaaagaagaa      540

gatcccgagc aaaagagaga gacccctgaa tctagaaatc aggggcaact ttacagtgag      600

ggggacagca gaggaggaga cagaaagcag aggcctggag aggagaggag gctggcacac      660

cagcaacaac gccaaggaag ggaggaggag gaggatgagg aggaggaggg tgaggagggt      720

gaggaggatg aggaggacga ggaggacccg gtaagaggag atatgttccg aatgccctct      780

cgatccccgc ttcctgctcc tcccagaggc acactgcgcc tgccaagcgg gtgctctctg      840

tcctacagga ccatcagctg catcaacgcc atgcttaccc agataccacc gctgacagca      900

ccacagataa caagtctgga gctcactggc aattccatcg cctccatccc agatgaagca      960

tttaatggat taccaaattt ggaaaggctt gatctgagta aaaataatat cacttcttca     1020

ggcataggtc caaaagcatt caagcttctg aagaagttaa tgcgtttgaa tatggatgga     1080

aataatttga tacagattcc ttcacaattg ccatctacat tagaagaact taaagtcaat     1140

gagaacaatc ttcaggctat cgatgaagaa agtttatcgg acttaaatca gttggtcacc     1200

ttagaattgg aaggaaacaa tctcagtgaa gccaatgtca atcctttagc tttcaaacct     1260

ttgaagagcc tagcctactt gcgtctggga aaaaataaat ttagaattat accgcagggt     1320

cttcctggtt ctattgagga attataccta gaaaataacc aaattgaaga aataactgaa     1380

atttgtttca atcataccag aaagatcaat gtcattgtac tacgttataa caaaattgaa     1440

gaaaatagga ttgctccttt agcctggata aatcaagaaa atctagaatc cattgatctc     1500

tcctacaaca agctctatca cgtcccgtcc tatctaccca agtccttgct gcacctagta     1560

ctccttggga accagattga acggatccct ggctatgtgt ttggccacat ggaaccaggc     1620

ctggaatact tgtacctgtc atttaacaaa cttgctgatg atggcatgga ccgtgtctcc     1680

ttctatgggg catatcattc tctgagagaa ttatttctgg atcacaatga cttaaaatct     1740

ataccacctg ggatacaaga aatgaaagca ctacattttc tgaggctgaa caacaacaag     1800

atacgctgtg tttcagatgc tgttctagag acagtgacaa acagatcaga tgtggccttt     1860

cctctctgg                                                             1869


<210>  3458
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  3458
agcaaaagca atgaaggagc agatggccca gttaaaaaca agaaaaaggg aaagaaagca       60

ggacctcctg gacccaatgg ccctccagga cccccaggac ctccaggacc ccagggaccc      120

ccaggaattc cagggattcc tggaattcca ggaacaactg ttatgggacc acctggtcct      180

ccaggtcctc ctggtcctca aggaccccct ggcctccagg gaccttctgg tgctgctgat      240

aaagctggaa ctcgagaaaa ccagccagct gtggtgcatc tacagggcca agggtcagca      300

attcaagtca agaatgatct ttcaggtgga gtgctcaatg actggtctcg catcactatg      360

aaccccaagg tgtttaagct acatccccgc agcggggagc tggaggtact ggtggacggc      420

acctacttca tctatagtca ggtagaagta tactacatca acttcactga ctttgccagc      480

tatgaggtgg tggtggatga gaagcccttc ctgcagtgca cacgcagcat cgagacgggc      540

aagaccaact acaacacttg ctataccgca ggcgtctgcc tcctcaaggc ccggcagaag      600

atcgccgtca agatggtgca cgctgacatc tccatcaaca tgagcaagca caccacgttc      660

tttggggcca tcaggctggg tgaagcccct gcatcc                                696


<210>  3459
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  3459
atggattgcc aagaaaatga gtactgggac caatggggac ggtgtgtcac ctgccaacgg       60

tgtggtcctg gacaggagct atccaaggat tgtggttatg gagagggtgg agatgcctac      120

tgcacagcct gccctcctcg caggtacaaa agcagctggg gccaccacag atgtcagagt      180

tgcatcacct gtgctgtcat caatcgtgtt cagaaggtca actgcacagc tacctctaat      240

gctgtctgtg gggactgttt gcccaggttc taccgaaaga cacgcattgg aggcctgcag      300

gaccaagagt gcatcccgtg cacgaagcag acccccacct ctgaggttca atgtgccttc      360

cagttgagct tagtggaggc agatgcaccc acagtgcccc ctcaggaggc caca            414


<210>  3460
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  3460
gaatactcaa actgcggtga gaacgagtac tacaaccaga ctacggggct gtgccaggag       60

tgccccccgt gtgggccggg agaggagccc tacctgtcct gtggctacgg caccaaagac      120

gaggactacg gctgcgtccc ctgcccggcg gagaagtttt ccaaaggagg ctaccagata      180

tgcaggcgtc acaaagactg tgagggcttc ttccgggcca ccgtgctgac accaggggac      240

gtggagaatg acgctgagtg tggcccttgc ctccctggct actacatgct ggagaacaga      300

ccgaggaaca tctatggcat ggtctgctac tcctgcctcc tggcaccccc caacaccaag      360

gaatgtgtgg gagccacttc aggagcttct gccaacttcc ctggcacctc gggcagcagc      420

accctgtctc ccttccagca cgcccacaaa gaactctcag gccaaggaca cctggccact      480

gcc                                                                    483


<210>  3461
<211>  1371
<212>  DNA
<213>  Homo Sapiens

<400>  3461
gatatttgtg atcccaatcc atgtgaaaat ggaggtatct gtttgccagg attggctgat       60

ggttcctttt cctgtgagtg tccagatggc ttcacagacc ccaactgttc tagtgttgtg      120

gaggttgcat cagatgaaga agaaccaact tcagcaggtc cctgcactcc taatccatgc      180

cataatggag gaacctgtga aataagtgaa gcataccgag gggatacatt cataggctat      240

gtttgtaaat gtccccgagg atttaatggg attcactgtc agcacaacat aaatgaatgc      300

gaagttgagc cttgcaaaaa tggtggaata tgtacagatc ttgttgctaa ctattcctgt      360

gagtgcccag gcgaatttat gggaagaaat tgtcaataca aatgctcagg cccactggga      420

attgaaggtg gaattatatc aaaccagcaa atcacagctt cctctactca ccgagctctt      480

tttggactcc aaaaatggta tccctactat gcacgtctta ataagaaggg gcttataaat      540

gcgtggacag ctgcagaaaa tgacagatgg ccgtggattc agataaattt gcaaaggaaa      600

atgagagtta ctggtgtgat tacccaagga gccaagagga ttggaagccc agagtatata      660

aaatcctaca aaattgccta cagtaatgat ggaaagactt gggcaatgta caaagtgaaa      720

ggcaccaatg aagacatggt gtttcgtgga aacattgata acaacactcc atatgctaac      780

tctttcacac cccccataaa agctcagtat gtaagactct atccccaagt ttgtcgaaga      840

cattgcactt tgcgaatgga acttcttggc tgtgaactgt cgggttgttc tgagcctctg      900

ggtatgaaat caggacatat acaagactat cagatcactg cctccagcat cttcagaacg      960

ctcaacatgg acatgttcac ttgggaacca aggaaagctc ggctggacaa gcaaggcaaa     1020

gtgaatgcct ggacctctgg ccacaatgac cagtcacaat ggttacaggt ggatcttctt     1080

gttccaacca aagtgactgg catcattaca caaggagcta aagattttgg tcatgtacag     1140

tttgttggct cctacaaact ggcttacagc aatgatggag aacactggac tgtataccag     1200

gatgaaaagc aaagaaaaga taaggttttc cagggaaatt ttgacaatga cactcacaga     1260

aaaaatgtca tcgaccctcc catctatgca cgacacataa gaatccttcc ttggtcctgg     1320

tacgggagga tcacattgcg gtcagagctg ctgggctgca cagaggagga a              1371


<210>  3462
<211>  1428
<212>  DNA
<213>  Homo Sapiens

<400>  3462
caggacaccg aagaaaccat cacgtacacg caatgcactg acggatatga gtgggatcct       60

gtgagacagc aatgcaaaga tattgatgaa tgtgacattg tcccagacgc ttgtaaaggt      120

ggaatgaagt gtgtcaacca ctatggagga tacctctgcc ttccgaaaac agcccagatt      180

attgtcaata atgaacagcc tcagcaggaa acacaaccag cagaaggaac ctcaggggca      240

accaccgggg ttgtagctgc cagcagcatg gcaaccagtg gagtgttgcc cgggggtggt      300

tttgtggcca gtgctgctgc agtcgcaggc cctgaaatgc agactggccg aaataacttt      360

gtcatccggc ggaacccagc tgaccctcag cgcattccct ccaacccttc ccaccgtatc      420

cagtgtgcag caggctacga gcaaagtgaa cacaacgtgt gccaagacat agacgagtgc      480

actgcaggga cgcacaactg tagagcagac caagtgtgca tcaatttacg gggatccttt      540

gcatgtcagt gccctcctgg atatcagaag cgaggggagc agtgcgtaga catagatgaa      600

tgtaccatcc ctccatattg ccaccaaaga tgcgtgaata caccaggctc attttattgc      660

cagtgcagtc ctgggtttca attggcagca aacaactata cctgcgtaga tataaatgaa      720

tgtgatgcca gcaatcaatg tgctcagcag tgctacaaca ttcttggttc attcatctgt      780

cagtgcaatc aaggatatga gctaagcagt gacaggctca actgtgaaga cattgatgaa      840

tgcagaacct caagctacct gtgtcaatat caatgtgtca atgaacctgg gaaattctca      900

tgtatgtgcc cccagggata ccaagtggtg agaagtagaa catgtcaaga tataaatgag      960

tgtgagacca caaatgaatg ccgggaggat gaaatgtgtt ggaattatca tggcggcttc     1020

cgttgttatc cacgaaatcc ttgtcaagat ccctacattc taacaccaga gaaccgatgt     1080

gtttgcccag tctcaaatgc catgtgccga gaactgcccc agtcaatagt ctacaaatac     1140

atgagcatcc gatctgatag gtctgtgcca tcagacatct tccagataca ggccacaact     1200

atttatgcca acaccatcaa tacttttcgg attaaatctg gaaatgaaaa tggagagttc     1260

tacctacgac aaacaagtcc tgtaagtgca atgcttgtgc tcgtgaagtc attatcagga     1320

ccaagagaac atatcgtgga cctggagatg ctgacagtca gcagtatagg gaccttccgc     1380

acaagctctg tgttaagatt gacaataata gtggggccat tttcattt                  1428


<210>  3463
<211>  1254
<212>  DNA
<213>  Homo Sapiens

<400>  3463
tctcctcagg attctgaaga gcccgacagc tacacggaat gcacagatgg ctatgagtgg       60

gacccagaca gccagcactg ccgggatgtc aacgagtgtc tgaccatccc tgaggcctgc      120

aagggggaaa tgaagtgcat caaccactac gggggctact tgtgcctgcc ccgctccgct      180

gccgtcatca acgacctaca cggcgaggga cccccgccac cagtgcctcc cgctcaacac      240

cccaacccct gcccaccagg ctatgagccc gacgatcagg acagctgtgt ggatgtggac      300

gagtgtgccc aggccctgca cgactgtcgc cccagccagg actgccataa cttgcctggc      360

tcctatcagt gcacctgccc tgatggttac cgcaagatcg ggcccgagtg tgtggacata      420

gacgagtgcc gctaccgcta ctgccagcac cgctgcgtga acctgcctgg ctccttccgc      480

tgccagtgcg agccgggctt ccagctgggg cctaacaacc gctcctgtgt tgatgtgaac      540

gagtgtgaca tgggggcccc atgcgagcag cgctgcttca actcctatgg gaccttcctg      600

tgtcgctgcc accagggcta tgagctgcat cgggatggct tctcctgcag tgatattgat      660

gagtgtagct actccagcta cctctgtcag taccgctgcg tcaacgagcc aggccgtttc      720

tcctgccact gcccacaggg ttaccagctg ctggccacac gcctctgcca agacattgat      780

gagtgtgagt ctggtgcgca ccagtgctcc gaggcccaaa cctgtgtcaa cttccatggg      840

ggctaccgct gcgtggacac caaccgctgc gtggagccct acatccaggt ctctgagaac      900

cgctgtctct gcccggcctc caaccctcta tgtcgagagc agccttcatc cattgtgcac      960

cgctacatga ccatcacctc ggagcggagc gtgcccgctg acgtgttcca gatccaggcg     1020

acctccgtct accccggtgc ctacaatgcc tttcagatcc gtgctggaaa ctcgcagggg     1080

gacttttaca ttaggcaaat caacaacgtc agcgccatgc tggtcctcgc ccggccggtg     1140

acgggccccc gggagtacgt gctggacctg gagatggtca ccatgaattc cctcatgagc     1200

taccgggcca gctctgtact gaggctcacc gtctttgtag gggcctacac cttc           1254


<210>  3464
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  3464
gatcgccaca ccgtcttctg gaacagttca aatcccaagt tccggaatga ggactacacc       60

atacatgtgc agctgaatga ctacgtggac atcatctgtc cgcactatga agatcactct      120

gtggcagacg ctgccatgga gcagtacata ctgtacctgg tggagcatga ggagtaccag      180

ctgtgccagc cccagtccaa ggaccaagtc cgctggcagt gcaaccggcc cagtgccaag      240

catggcccgg agaagctgtc tgagaagttc cagcgcttca cacctttcac cctgggcaag      300

gagttcaaag aaggacacag ctactactac atctccaaac ccatccacca gcatgaagac      360

cgctgcttga ggttgaaggt gactgtcagt ggcaaaatca ctcacagtcc tcaggcccat      420

gtcaatccac aggagaagag acttgcagca gatgacccag aggtgcgggt tctacatagc      480

atcgctcaca gt                                                          492


<210>  3465
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  3465
cgcgccgagg acgccgcccg cgccaactcg gaccgctacg ccgtctactg gaaccgcagc       60

aaccccaggt tccacgcagg cgcgggggac gacggcgggg gctacacggt ggaggtgagc      120

atcaatgact acctggacat ctactgcccg cactatgggg cgccgctgcc gccggccgag      180

cgcatggagc actacgtgct gtacatggtc aacggcgagg gccacgcctc ctgcgaccac      240

cgccagcgcg gcttcaagcg ctgggagtgc aaccggcccg cggcgcccgg ggggccgctc      300

aagttctcgg agaagttcca gctcttcacg cccttctccc tgggcttcga gttccggccc      360

ggccacgagt attactacat ctctgccacg cctcccaatg ctgtggaccg gccctgcctg      420

cgactgaagg tgtacgtgcg gccgaccaac gagaccctgt acgaggctcc tgagcccatc      480

ttcaccagca at                                                          492


<210>  3466
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  3466
caagggcccg gaggggcgct gggaaaccgg catgcggtgt actggaacag ctccaaccag       60

cacctgcggc gagagggcta caccgtgcag gtgaacgtga acgactatct ggatatttac      120

tgcccgcact acaacagctc gggggtgggc cccggggcgg gaccggggcc cggaggcggg      180

gcagagcagt acgtgctgta catggtgagc cgcaacggct accgcacctg caacgccagc      240

cagggcttca agcgctggga gtgcaaccgg ccgcacgccc cgcacagccc catcaagttc      300

tcggagaagt tccagcgcta cagcgccttc tctctgggct acgagttcca cgccggccac      360

gagtactact acatctccac gcccactcac aacctgcact ggaagtgtct gaggatgaag      420

gtgttcgtct gctgcgcctc cacatcgcac tccggggaga agccggtccc cactctcccc      480

cagttcacca tgggccccaa tgtgaagatc aacgtgctgg aagactttga gggagagaac      540

cctcaggtgc ccaagcttga gaagagcatc agcggg                                576


<210>  3467
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3467
caggacccgg gctccaaggc cgtcgccgac cgctacgctg tctactggaa cagcagcaac       60

cccagattcc agaggggtga ctaccatatt gatgtctgta tcaatgacta cctggatgtt      120

ttctgccctc actatgagga ctccgtccca gaagataaga ctgagcgcta tgtcctctac      180

atggtgaact ttgatggcta cagtgcctgc gaccacactt ccaaagggtt caagagatgg      240

gaatgtaacc ggcctcactc tccaaatgga ccgctgaagt tctctgaaaa attccagctc      300

ttcactccct tttctctagg atttgaattc aggccaggcc gagaatattt ctacatctcc      360

tctgcaatcc cagataatgg aagaaggtcc tgtctaaagc tcaaagtctt tgtgagacca      420

acaaatagct gtatgaaaac tataggtgtt catgatcgtg ttttcgatgt taacgacaaa      480

gtagaaaatt cattagaacc agcagatgac accgtacatg agtcagccga gccatcccgc      540

ggcgagaac                                                              549


<210>  3468
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  3468
ctggccaaga acctggagcc cgtatcctgg agctccctca accccaagtt cctgagtggg       60

aagggcttgg tgatctatcc gaaaattgga gacaagctgg acatcatctg cccccgagca      120

gaagcagggc ggccctatga gtactacaag ctgtacctgg tgcggcctga gcaggcagct      180

gcctgtagca cagttctcga ccccaacgtg ttggtcacct gcaataggcc agagcaggaa      240

atacgcttta ccatcaagtt ccaggagttc agccccaact acatgggcct ggagttcaag      300

aagcaccatg attactacat tacctcaaca tccaatggaa gcctggaggg gctggaaaac      360

cgggagggcg gtgtgtgccg cacacgcacc atgaagatca tcatgaaggt tgggcaagat      420

cccaatgctg tgacgcctga gcagctgact accagcaggc ccagcaagga ggcagacaac      480

actgtcaaga tggccacaca ggcccctggt agtcggggct ccctgggtga ctctgatggc      540

aagcatgaga ctgtgaacca ggaagagaag agtggcccag gtgcaagtgg gggcagcagc      600

ggggaccctg atggcttctt caactccaag                                       630


<210>  3469
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  3469
atagttttag agcctatcta ttggaattcc tcgaactcca aatttctacc tggacaagga       60

ctggtactat acccacagat aggagacaaa ttggatatta tttgccccaa agtggactct      120

aaaactgttg gccagtatga atattataaa gtttatatgg ttgataaaga ccaagcagac      180

agatgcacta ttaagaagga aaatacccct ctcctcaact gtgccaaacc agaccaagat      240

atcaaattca ccatcaagtt tcaagaattc agccctaacc tctggggtct agaatttcag      300

aagaacaaag attattacat tatatctaca tcaaatgggt ctttggaggg cctggataac      360

caggagggag gggtgtgcca gacaagagcc atgaagatcc tcatgaaagt tggacaagat      420

gcaagttctg ctggatcaac caggaataaa gatccaacaa gacgtccaga actagaagct      480

ggtacaaatg gaagaagttc gacaacaagt ccctttgtaa aaccaaatcc aggttctagc      540

acagacggca acagcgccgg acattcgggg aacaacatcc tcggttccga agtggcctta      600

tttgca                                                                 606


<210>  3470
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  3470
ctcagcctgg agcctgtcta ctggaactcg gcgaataaga ggttccaggc agagggtggt       60

tatgtgctgt accctcagat cggggaccgg ctagacctgc tctgccccag ggcccggcct      120

cctggccctc actcctctcc taattatgag ttctacaagc tgtacctggt agggggtgct      180

cagggccggc gctgtgaggc accccctgcc ccaaacctcc ttctcacttg tgatcgccca      240

gacctggatc tccgcttcac catcaagttc caggagtata gccctaatct ctggggccac      300

gagttccgct cgcaccacga ttactacatc attgccacat cggatgggac ccgggagggc      360

ctggagagcc tgcagggagg tgtgtgccta accagaggca tgaaggtgct tctccgagtg      420

ggacaaagtc cccgaggagg ggctgtcccc cgaaaacctg tgtctgaaat gcccatggaa      480

agagaccgag gggcagccca cagcctggag cctgggaagg agaacctgcc aggtgacccc      540

accagcaatg caacctcccg gggtgctgaa ggccccctgc cccctcccag catgcct         597


<210>  3471
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  3471
aatagtgact ctgaatgtcc cctgtcccac gatgggtact gcctccatga tggtgtgtgc       60

atgtatattg aagcattgga caagtatgca tgcaactgtg ttgttggcta catcggggag      120

cgatgtcagt accgagacct gaagtggtgg gaactgcgc                             159


<210>  3472
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  3472
catctggagt gctcctgcca caacaacagc acgtgtgagc ctgccacggg cacctgccgc       60

tgcggccccg gcttctatgg ccaggcctgc gagcacccct gtccccctgg cttccacggg      120

gctggctgcc aggggttgtg ctggtgtcaa catggagccc cctgcgaccc catcagtggc      180

cgatgcctct gccctgccgg cttccacggc cacttctgtg agagggggtg tgagccaggt      240

tcatttggag agggctgcca ccagcgctgt gactgtgacg ggggggcacc ctgtgaccct      300

gtcaccggtc tctgcctttg cccaccaggg cgctcaggag ccacctgtaa cctggattgc      360

agaaggggcc agtttgggcc cagctgcacc ctgcactgtg actgcggggg tggggctgac      420

tgcgaccctg tcagtgggca gtgtcactgt gtggatggct acatggggcc cacgtgccgg      480

gaaggtgggc ccctccggct ccccgagaac ccgtccttag cccagggctc agcgggcaca      540

ctgcccgcct ccagcagacc cacatcccgg agcggtggac cagcgaggca c               591


<210>  3473
<211>  1596
<212>  DNA
<213>  Homo Sapiens

<400>  3473
aacgcggcca gtgcaaggca tcacgggttg ttagcatcgg cacgtcagcc tggggtctgt       60

cactatggaa ctaaactggc ctgctgctac ggctggagaa gaaacagcaa gggagtctgt      120

gaagctacat gcgaacctgg atgtaagttt ggtgagtgcg tgggaccaaa caaatgcaga      180

tgctttccag gatacaccgg gaaaacctgc agtcaagatg tgaatgagtg tggaatgaaa      240

ccccggccat gccaacacag atgtgtgaat acacacggaa gctacaagtg cttttgcctc      300

agtggccaca tgctcatgcc agatgctacg tgtgtgaact ctaggacatg tgccatgata      360

aactgtcagt acagctgtga agacacagaa gaagggccac agtgcctgtg tccatcctca      420

ggactccgcc tggccccaaa tggaagagac tgtctagata ttgatgaatg tgcctctggt      480

aaagtcatct gtccctacaa tcgaagatgt gtgaacacat ttggaagcta ctactgcaaa      540

tgtcacattg gtttcgaact gcaatatatc agtggacgat atgactgtat agatataaat      600

gaatgtacta tggatagcca tacgtgcagc caccatgcca attgcttcaa tacccaaggg      660

tccttcaagt gtaaatgcaa gcagggatat aaaggcaatg gacttcggtg ttctgctatc      720

cctgaaaatt ctgtgaagga agtcctcaga gcacctggta ccatcaaaga cagaatcaag      780

aagttgcttg ctcacaaaaa cagcatgaaa aagaaggcaa aaattaaaaa tgttacccca      840

gaacccacca ggactcctac ccctaaggtg aacttgcagc ccttcaacta tgaagagata      900

gtttccagag gcgggaactc tcatggaggt aaaaaaggga atgaagagaa aatgaaagag      960

gggcttgagg atgagaaaag agaagagaaa gccctgaaga atgacataga ggagcgaagc     1020

ctgcgaggag atgtgttttt ccctaaggtg aatgaagcag gtgaattcgg cctgattctg     1080

gtccaaagga aagcgctaac ttccaaactg gaacataaag atttaaatat ctcggttgac     1140

tgcagcttca atcatgggat ctgtgactgg aaacaggata gagaagatga ttttgactgg     1200

aatcctgctg atcgagataa tgctattggc ttctatatgg cagttccggc cttggcaggt     1260

cacaagaaag acattggccg attgaaactt ctcctacctg acctgcaacc ccaaagcaac     1320

ttctgtttgc tctttgatta ccggctggcc ggagacaaag tcgggaaact tcgagtgttt     1380

gtgaaaaaca gtaacaatgc cctggcatgg gagaagacca cgagtgagga tgaaaagtgg     1440

aagacaggga aaattcagtt gtatcaagga actgatgcta ccaaaagcat catttttgaa     1500

gcagaacgtg gcaagggcaa aaccggcgaa atcgcagtgg atggcgtctt gcttgtttca     1560

ggcttatgtc cagatagcct tttatctgtg gatgac                               1596


<210>  3474
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  3474
taccggcccg gccgtagggt gtgtgctgtc cgggctcacg gggaccctgt ctccgagtcg       60

ttcgtgcagc gtgtgtacca gcccttcctc accacctgcg acgggcaccg ggcctgcagc      120

acctaccgaa ccatctatag gaccgcctac cgccgcagcc ctgggctggc ccctgccagg      180

cctcgctacg cgtgctgccc cggctggaag aggaccagcg ggcttcctgg ggcctgtgga      240

gcagcaatat gccagccgcc atgccggaac ggagggagct gtgtccagcc tggccgctgc      300

cgctgccctg caggatggcg gggtgacact tgccagtcag atgtggatga atgcagtgct      360

aggaggggcg gctgtcccca gcgctgcatc aacaccgccg gcagttactg gtgccagtgt      420

tgggaggggc acagcctgtc tgcagacggt acactctgtg tgcccaaggg agggcccccc      480

agggtggccc ccaacccgac aggagtggac agtgcaatga aggaagaagt gcagaggctg      540

cagtccaggg tggacctgct ggaggagaag ctgcagctgg tgctggcccc actgcacagc      600

ctggcctcgc aggcactgga gcatgggctc ccggaccccg gcagcctcct ggtgcactcc      660

ttccagcagc tcggccgcat cgactccctg agcgagcaga tttccttcct ggaggagcag      720

ctggggtcct gctcctgcaa gaaagactcg                                       750


<210>  3475
<211>  2955
<212>  DNA
<213>  Homo Sapiens

<400>  3475
ctccgagcgg ccatccgaaa accaggcaag gtagggcctc ctcttgacat caagctgggc       60

gcattgaact gtacggcttt cagcatccag tggaaaatgc caaggcatcc tggaagtccc      120

atccttgggt acactgtctt ttactctgag gttggcgcag ataaatccct gcaggagcag      180

ttgcacagcg tgcctctcag ccgggacatc ccgaccacgg aggaagtgat tggagatttg      240

aaaccaggca ctgaatatcg tgtgagcata gcagcttaca gccaggctgg caaagggcgg      300

ctgagctctc ctcggcatgt caccactttg tcccaagatt cctgcctgcc tcctgcagct      360

ccccagcagc cacatgtcat tgtggtttcg gattctgagg tggccctgtc ttggaaacct      420

ggagcgagtg aaggaagcgc ccctattcag tactattctg tggaattcat caggccagat      480

ttcgacaaga agtggacctc aatccatgag cggatccaga tggactccat ggttatcaag      540

ggcctcgatc cagataccaa ctaccagttt gccgtgaggg caatgaattc ccatggcccc      600

agcccccgca gctggcccag tgacatcatc cggaccctct gccctgagga ggcgggaagt      660

ggccgctatg gaccccgtta tatcaccgac atgggagctg gtgaggatga tgaaggattt      720

gaagacgact tagatttgga tatttccttt gaggaggtta aaccacttcc tgctaccaaa      780

ggagggaata agaaattttt ggtggaaagc aagaagatgt ctatatctaa cccaaagacc      840

atttctaggc tcatcccccc tacctcagca tctctccctg tgaccacggt ggctccccag      900

cccattccca tacagagaaa ggggaagaat ggtgtggcca taatgtcaag gctctttgac      960

atgccttgtg atgaaactct ctgctctgct gacagcttct gtgtcaatga ctacacctgg     1020

gggggctcgc gatgccagtg caccctgggc aaaggtggtg agagctgctc agaagatatt     1080

gttatccagt atcctcagtt ctttggccac tcctatgtaa cgtttgaacc tctgaagaat     1140

tcttatcagg catttcaaat tactcttgaa tttagggcgg aggcagagga tggcttactg     1200

ctctactgtg gggagaacga acacgggagg ggggatttca tgtccctggc tatcatccga     1260

cgctccctgc agttcaggtt taattgtgga actggggttg ccatcatcgt aagtgagacc     1320

aaaatcaaac tagggggttg gcacatggtt atgctctaca gagatgggct gaacgggctg     1380

ctgcagctga acaatggcac cccagtgaca ggccagtctc agggccaata cagtaaaatt     1440

actttccgga cacctctcta tcttggtggc gctcccagcg cttactggtt ggttagagca     1500

acagggacaa accgaggctt tcaaggctgt gtgcagtcgc tcgctgtgaa tgggaggaga     1560

attgacatga ggccctggcc cctgggaaaa gcactcagtg gggctgatgt gggggaatgc     1620

agcagtggaa tctgtgatga ggcctcgtgc atccatggtg gcacctgcac agcaatcaaa     1680

gccgactcct acatttgcct ctgtcccctt gggtttaaag gtcgacactg tgaagatgct     1740

ttcaccttga ccattcctca gttcagagag tctctgagat cttacgctgc aactccctgg     1800

ccactggagc cccagcatta cctttccttc atggaatttg agatcacatt tcggccagac     1860

tcaggagatg gtgtcctcct gtacagctat gacacaggca gcaaagactt cctgtccatc     1920

aacttggcag ggggccacgt ggagttccgc tttgactgtg gctctgggac cggtgtcctc     1980

aggagtgaag atcccctcac cctgggcaac tggcacgagc ttcgtgtatc tcgcacagca     2040

aagaatggaa tcttacaggt ggataagcag aagatagtgg agggaatggc agagggaggc     2100

ttcacacaga ttaagtgcaa cacagacatt ttcattggcg gagtccccaa ttatgatgat     2160

gtgaagaaga actcgggtgt cctgaagcct ttcagcggga gcatccagaa gatcatcctg     2220

aatgaccgaa ccatccatgt gaagcatgac ttcacctccg gagtgaatgt ggagaatgcg     2280

gcccacccct gtgtgagagc cccttgtgcc catgggggca gctgccggcc caggaaggag     2340

ggctatgact gtgactgccc cttgggcttt gaggggcttc actgccagaa agcgatcata     2400

gaagccattg agatcccgca gtttatcggc cgcagttacc tgacgtatga caacccagat     2460

atcttgaaga gggtgtcagg atcaagatca aatgtgttca tgaggtttaa aacaactgcc     2520

aaggatggcc ttttgctgtg gaggggagac agccccatga gacccaacag cgacttcatt     2580

tccttgggcc ttcgggatgg agccctcgtg ttcagctata acctgggcag tggtgtggca     2640

tccatcatgg tgaatggctc cttcaacgat ggtcggtggc accgagttaa ggccgttagg     2700

gatggccagt caggaaagat aaccgtggat gactatggag ccagaacagg caaatcccca     2760

ggcatgatgc ggcagcttaa catcaatgga gctctgtatg tgggtggaat gaaggaaatt     2820

gctctgcaca ctaacaggca atatatgaga gggctcgtgg gctgtatctc tcacttcacc     2880

ctgtccaccg attaccacat ttccctcgtg gaagatgccg tggatggaaa aaacatcaac     2940

acttgtggag ccaag                                                      2955


<210>  3476
<211>  1863
<212>  DNA
<213>  Homo Sapiens

<400>  3476
ctggaggaaa agaaagtttg ccaaggcacg agtaacaagc tcacgcagtt gggcactttt       60

gaagatcatt ttctcagcct ccagaggatg ttcaataact gtgaggtggt ccttgggaat      120

ttggaaatta cctatgtgca gaggaattat gatctttcct tcttaaagac catccaggag      180

gtggctggtt atgtcctcat tgccctcaac acagtggagc gaattccttt ggaaaacctg      240

cagatcatca gaggaaatat gtactacgaa aattcctatg ccttagcagt cttatctaac      300

tatgatgcaa ataaaaccgg actgaaggag ctgcccatga gaaatttaca ggaaatcctg      360

catggcgccg tgcggttcag caacaaccct gccctgtgca acgtggagag catccagtgg      420

cgggacatag tcagcagtga ctttctcagc aacatgtcga tggacttcca gaaccacctg      480

ggcagctgcc aaaagtgtga tccaagctgt cccaatggga gctgctgggg tgcaggagag      540

gagaactgcc agaaactgac caaaatcatc tgtgcccagc agtgctccgg gcgctgccgt      600

ggcaagtccc ccagtgactg ctgccacaac cagtgtgctg caggctgcac aggcccccgg      660

gagagcgact gcctggtctg ccgcaaattc cgagacgaag ccacgtgcaa ggacacctgc      720

cccccactca tgctctacaa ccccaccacg taccagatgg atgtgaaccc cgagggcaaa      780

tacagctttg gtgccacctg cgtgaagaag tgtccccgta attatgtggt gacagatcac      840

ggctcgtgcg tccgagcctg tggggccgac agctatgaga tggaggaaga cggcgtccgc      900

aagtgtaaga agtgcgaagg gccttgccgc aaagtgtgta acggaatagg tattggtgaa      960

tttaaagact cactctccat aaatgctacg aatattaaac acttcaaaaa ctgcacctcc     1020

atcagtggcg atctccacat cctgccggtg gcatttaggg gtgactcctt cacacatact     1080

cctcctctgg atccacagga actggatatt ctgaaaaccg taaaggaaat cacagggttt     1140

ttgctgattc aggcttggcc tgaaaacagg acggacctcc atgcctttga gaacctagaa     1200

atcatacgcg gcaggaccaa gcaacatggt cagttttctc ttgcagtcgt cagcctgaac     1260

ataacatcct tgggattacg ctccctcaag gagataagtg atggagatgt gataatttca     1320

ggaaacaaaa atttgtgcta tgcaaataca ataaactgga aaaaactgtt tgggacctcc     1380

ggtcagaaaa ccaaaattat aagcaacaga ggtgaaaaca gctgcaaggc cacaggccag     1440

gtctgccatg ccttgtgctc ccccgagggc tgctggggcc cggagcccag ggactgcgtc     1500

tcttgccgga atgtcagccg aggcagggaa tgcgtggaca agtgcaacct tctggagggt     1560

gagccaaggg agtttgtgga gaactctgag tgcatacagt gccacccaga gtgcctgcct     1620

caggccatga acatcacctg cacaggacgg ggaccagaca actgtatcca gtgtgcccac     1680

tacattgacg gcccccactg cgtcaagacc tgcccggcag gagtcatggg agaaaacaac     1740

accctggtct ggaagtacgc agacgccggc catgtgtgcc acctgtgcca tccaaactgc     1800

acctacggat gcactgggcc aggtcttgaa ggctgtccaa cgaatgggcc taagatcccg     1860

tcc                                                                   1863


<210>  3477
<211>  1173
<212>  DNA
<213>  Homo Sapiens

<400>  3477
gattgctggc tgatagaggg cgacaaaggt tttgtctggc ttgcgatatg ctcacaaaat       60

caacctccct acgaggctat accgcagcag atcaactcaa caattgtcga tcttaggtta      120

aacgaaaata ggatcagatc agtgcaatac gcatctcttt ccagatttgg taacttgact      180

tatcttaatc taacaaagaa cgaaataggc tatatcgagg acggagcgtt ctctggtcag      240

ttcaaccttc aagttcttca gcttggatac aataggctta ggaatttaac tgagggtatg      300

ttgagaggac ttggaaagtt agagtattta tatctgcagg ctaatctaat tgaagttgta      360

atggcttcta gtttttggga gtgtcccaac atagtgaata ttgacctttc aatgaacagg      420

attcagcaat tgaactcagg caccttcgcg ggattggcca aactatctgt ttgcgaatta      480

tacagcaatc ctttctattg cagttgcgag ttgttgggat tcttacgttg gctggcggcg      540

tttacaaatg cgacccagac atacgacagg atgcagtgtg agagccctcc cgtttactcc      600

ggctactatt tacttggtca gggtcgtcgt ggacatagga gtatcttatc aaaacttcag      660

agcgtgtgta cggaggacag ttacgccgcg gaggtagtcg gcccacctag accagctagt      720

gggagaagcc agccaggccg tagtcccccc ccacctcctc cccccgagcc gtctgatatg      780

ccttgtgcag acgacgagtg cttttcaggc gacggtacta ctccacttgt tgcacttcca      840

accctggcta ctcaggccga agcgagaccc ctaattaagg ttaaacagtt gacgcagaat      900

tctgcgacaa tcaccgtgca actacctagc cccttccata gaatgtacac gttggaacat      960

ttcaacaata gcaaagcctc cactgtgtca aggttgacaa aagctcagga agaaatacgt     1020

ctaaccaact tgttcacgtt gacaaactac acttactgcg tggtgtcaac gagtgcgggg     1080

ttaagacaca accatacctg tctgactata tgtctaccca gacttccatc accgccgggt     1140

cccgttccat ctcctagtac agccacccac tat                                  1173


<210>  3478
<211>  1125
<212>  DNA
<213>  Homo Sapiens

<400>  3478
gattgttggt taattgaagg cgacaaaggg tacgtctggc tagccatctg ctcccagaat       60

cagcccccct atgaaaccat cccccaacac atcaatagta ccgtccacga ccttagatta      120

aatgagaata aattgaaggc ggtactttac agcagcctga acagatttgg aaacctgaca      180

gatcttaatc ttacgaaaaa cgagattagt tatatcgaag acggggcgtt tctaggtcag      240

agctcattgc aagtactgca gttgggctac aataagctga gtaatctaac agaaggtatg      300

ctgagaggca tgagtagact tcaattcttg ttcgtgcagc ataatctgat cgaggttgtg      360

acgcccactg cattttcaga gtgtccttca cttatttcca tagaccttag ttctaacagg      420

ttatctagat tagacggcgc tacgtttgca agtcttgctt ctctgatggt ttgtgagtta      480

gcaggtaacc ccttcaactg tgaatgtgac ttgttcgggt tccttgcctg gcttgtcgta      540

tttaataatg ttaccaagaa ctatgaccgt ctacagtgtg aatctccaag agagttcgct      600

ggttaccccc tattagttcc gaggccttat cactccctga atgctattac tgtgttgcag      660

gcgaaatgca ggaatggaag tcttccggcc aggccggtgt cacatcctac accctactcc      720

actgacgcgc aacgtgaacc cgacgaaaac tctggattca atcctgatga aattttaagt      780

gtcgaacccc cggccagcag taccactgac gcctcagcgg gccccgcaat taaactacat      840

cacgtgacat tcacctctgc aaccctggtt gtgattatac cacatccgta ctctaagatg      900

tatattcttg tccaatacaa taacagttat ttctctgacg ttatgacact taagaataag      960

aaggagatag tgacgctaga caagctaagg gcacataccg agtacacctt ttgtgtgacg     1020

agtttaagaa actcccgtcg ttttaatcac acttgtctga cgtttacaac ccgtgatccc     1080

gtgcccggcg accttgcccc tagcacatca actaccacgc attac                     1125


<210>  3479
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  3479
atgcatgagg aatgtgtctt tcctttcacc tacaagggat ctgtttactt cacttgcacc       60

catattcata gcttatcccc ttggtgtgcc accagagccg tgtacaacgg ccagtggaag      120

tactgccaga gtgaagatta cccacgctgt atcttccctt tcatctatcg aggaaaggct      180

tataacagct gcatctccca gggcagcttc ttaggcagtc tgtggtgctc agtcacctct      240

gtcttcgatg agaaacagca gtggaaattc tgtgaaacga atgagtatgg gggaaattct      300

ctcaggaagc cctgcatctt cccctccatc tacagaaata atgtggtctc tgattgcatg      360

gaggatgaaa gcaacaagct ctggtgccca accacagaga acatggataa ggatggaaag      420

tggagtttct gtgccgacac cagaatttcc gcgttggtcc ctggctttcc ttgtcacttt      480

ccgttcaact ataaaaacaa gaattatttt aactgcacta acaaaggatc aaaggagaac      540

cttgtgtggt gtgcaacttc ttacaactac gaccaagacc acacctgggt gtattgc         597


<210>  3480
<211>  1239
<212>  DNA
<213>  Homo Sapiens

<400>  3480
caaaattgca ccaagacacc ttgtctccca aatgcaaaat gtgaaatacg caatggaatt       60

gaagcctgct attgcaacat gggattttca ggaaatggtg tcacaatttg tgaagatgat      120

aatgaatgtg gaaatttaac tcagtcctgt ggcgaaaatg ctaattgcac taacacagaa      180

ggaagttatt attgtatgtg tgtacctggc ttcagatcca gcagtaacca agacaggttt      240

atcactaatg atggaaccgt ctgtatagaa aatgtgaatg caaactgcca tttagataat      300

gtctgtatag ctgcaaatat taataaaact ttaacaaaaa tcagatccat aaaagaacct      360

gtggctttgc tacaagaagt ctatagaaat tctgtgacag atctttcacc aacagatata      420

attacatata tagaaatatt agctgaatca tcttcattac taggttacaa gaacaacact      480

atctcagcca aggacaccct ttctaactca actcttactg aatttgtaaa aaccgtgaat      540

aattttgttc aaagggatac atttgtagtt tgggacaagt tatctgtgaa tcataggaga      600

acacatctta caaaactcat gcacactgtt gaacaagcta ctttaaggat atcccagagc      660

ttccaaaaga ccacagagtt tgatacaaat tcaacggata tagctctcaa agttttcttt      720

tttgattcat ataacatgaa acatattcat cctcatatga atatggatgg agactacata      780

aatatatttc caaagagaaa agctgcatat gattcaaatg gcaatgttgc agttgcattt      840

gtatattata agagtattgg tcctttgctt tcatcatctg acaacttctt attgaaacct      900

caaaattatg ataattctga agaggaggaa agagtcatat cttcagtaat ttcagtctca      960

atgagctcaa acccacccac attatatgaa cttgaaaaaa taacatttac attaagtcat     1020

cgaaaggtca cagataggta taggagtcta tgtgcatttt ggaattactc acctgatacc     1080

atgaatggca gctggtcttc agagggctgt gagctgacat actcaaatga gacccacacc     1140

tcatgccgct gtaatcacct gacacatttt gcaattttga tgtcctctgg tccttccatt     1200

ggtattaaag attataatat tcttacaagg atcactcaa                            1239


<210>  3481
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  3481
gacggcagtg ccccagattc gccttttaca agtccacctc tcagagaaga aataatggca       60

aataactttt ccttggagag tcataacata tcactgactg aacattctag tatgccagta      120

gaaaaaaata tcactttaga aaggccttct aatgtaaatc tcacatgcca gttcacaaca      180

tctggggatt tgaatgcagt aaatgtgact tggaaaaaag atggtgaaca acttgagaat      240

aattatcttg tcagtgcaac aggaagcacc ttgtataccc aatacaggtt caccatcatt      300

aatagcaaac aaatgggaag ttattcttgt ttctttcgag aggaaaagga acaaagggga      360

acatttaatt tcaaagtccc tgaacttcat gggaaaaaca agccattgat ctcttacgta      420

ggggattcta ctgtcttgac atgtaaatgt caaaattgtt ttcctttaaa ttggacctgg      480

tacagtagta atgggagtgt aaaggttcct gttggtgttc aaatgaataa atatgtgatc      540

aatggaacat atgctaacga aacaaagctg aagataacac aacttttgga ggaagatggg      600

gaatcttact ggtgccgtgc actattccaa ttaggcgaga gtgaagaaca cattgagctt      660

gtggtgctga gctatttggt gccc                                             684


<210>  3482
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  3482
aacagcacag gtgttttaga ggcagctaat aattcacttg ttgttactac aacaaaacca       60

tctataacaa caccaaacac agaatcatta cagaaaaatg ttgtcacacc aacaactgga      120

acaactccta aaggaacaat caccaatgaa ttacttaaaa tgtctctgat gtcaacagct      180

acttttttaa caagtaaaga tgaaggattg aaagccacaa ccactgatgt caggaagaat      240

gactccatca tttcaaacgt aacagtaaca agtgttacac ttccaaatgc tgtttcaaca      300

ttacaaagtt ccaaacccaa gactgaaact cagagttcaa ttaaaacaac agaaatacca      360

ggcacaccag aaaatggaaa tgatcaacct cagtctgata aagagagcgt gaagcttctt      420

accgttaaga caatttctca tgagtctggt gagcactctg cacaaggaaa aaccaagaac      480


<210>  3483
<211>  1737
<212>  DNA
<213>  Homo Sapiens

<400>  3483
cacataagac ccacacggaa accaaacaca aagggtaata actgtagaga cagtaccttg       60

tgcccagctt atgccacctg caccaataca gtggacagtt actattgcgc ttgcaaacaa      120

ggcttcctgt ccagcaatgg gcaaaatcac ttcaaggatc caggagtgcg atgcaaagat      180

attgatgaat gttctcaaag cccccagccc tgtggtccta actcatcctg caaaaacctg      240

tcagggaggt acaagtgcag ctgtttagat ggtttctctt ctcccactgg aaatgactgg      300

gtcccaggaa agccgggcaa tttctcctgt actgatatca atgagtgcct caccagcagc      360

gtctgccctg agcattctga ctgtgtcaac tccatgggaa gctacagttg cagctgtcaa      420

gttggattca tctctagaaa ctccacctgt gaagacgtgg atgaatgtgc agatccaaga      480

gcttgcccag agcatgcaac ttgtaataac actgttggaa actactcttg tttctgcaac      540

ccaggatttg aatccagcag tggccacttg agtttccagg gtctcaaagc atcgtgtgaa      600

gatattgatg aatgcactga aatgtgcccc atcaattcaa catgcaccaa cactcctggg      660

agctactttt gcacctgcca ccctggcttt gcaccaagca atggacagtt gaatttcaca      720

gaccaaggag tggaatgtag agatattgat gagtgccgcc aagatccatc aacctgtggt      780

cctaattcta tctgcaccaa tgccctgggc tcctacagct gtggctgcat tgcaggcttt      840

catcccaatc cagaaggctc ccagaaagat ggcaacttca gctgccaaag ggttctcttc      900

aaatgtaagg aagatgtgat acccgataat aagcagatcc agcaatgcca agagggaacc      960

gcagtgaaac ctgcatatgt ctccttttgt gcacaaataa ataacatctt cagcgttctg     1020

gacaaagtgt gtgaaaataa aacgaccgta gtttctctga agaatacaac tgagagcttt     1080

gtccctgtgc ttaaacaaat atccacgtgg actaaattca ccaaggaaga gacgtcctcc     1140

ctggccacag tcttcctgga gagtgtggaa agcatgacac tggcatcttt ttggaaaccc     1200

tcagcaaata tcactccggc tgttcggacg gaatacttag acattgagag caaagttatc     1260

aacaaagaat gcagtgaaga gaatgtgacg ttggacttgg tagccaaggg ggataagatg     1320

aagatcgggt gttccacaat tgaggaatct gaatccacag agaccactgg tgtggctttt     1380

gtctcctttg tgggcatgga atcggtttta aatgagcgct tcttcaaaga ccaccaggct     1440

cccttgacca cctctgagat caagctgaag atgaattctc gagtcgttgg gggcataatg     1500

actggagaga agaaagacgg cttctcagat ccaatcatct acactctgga gaacattcag     1560

ccaaagcaga agtttgagag gcccatctgt gtttcctgga gcactgatgt gaagggtgga     1620

agatggacat cctttggctg tgtgatcctg gaagcttctg agacatatac catctgcagc     1680

tgtaatcaga tggcaaatct tgccgttatc atggcgtctg gggagctcac gatggac        1737


<210>  3484
<211>  2484
<212>  DNA
<213>  Homo Sapiens

<400>  3484
aaaccaagct gtgccaaaga agttaaaagt tgcaaaggtc gctgtttcga gagaacattt       60

gggaactgtc gctgtgatgc tgcctgtgtt gagcttggaa actgctgttt agattaccag      120

gagacgtgca tagaaccaga acatatatgg acttgcaaca aattcaggtg tggtgagaaa      180

aggttgacca gaagcctctg tgcctgttca gatgactgca aggacaaggg cgactgctgc      240

atcaactaca gttctgtgtg tcaaggtgag aaaagttggg tagaagaacc atgtgagagc      300

attaatgagc cacagtgccc agcagggttt gaaacgcctc ctaccctctt attttctttg      360

gatggattca gggcagaata tttacacact tggggtggac ttcttcctgt tattagcaaa      420

ctaaaaaaat gtggaacata tactaaaaac atgagaccgg tatatccaac aaaaactttc      480

cccaatcact acagcattgt caccggattg tatccagaat ctcatggcat aatcgacaat      540

aaaatgtatg atcccaaaat gaatgcttcc ttttcactta aaagtaaaga gaaatttaat      600

cctgagtggt acaaaggaga accaatttgg gtcacagcta agtatcaagg cctcaagtct      660

ggcacatttt tctggccagg atcagatgtg gaaattaacg gaattttccc agacatctat      720

aaaatgtata atggttcagt accatttgaa gaaaggattt tagctgttct tcagtggcta      780

cagcttccta aagatgaaag accacacttt tacactctgt atttagaaga accagattct      840

tcaggtcatt catatggacc agtcagcagt gaagtcatca aagccttgca gagggttgat      900

ggtatggttg gtatgctgat ggatggtctg aaagagctga acttgcacag atgcctgaac      960

ctcatcctta tttcagatca tggcatggaa caaggcagtt gtaagaaata catatatctg     1020

aataaatatt tgggggatgt taaaaatatt aaagttatct atggacctgc agctcgattg     1080

agaccctctg atgtcccaga taaatactat tcatttaact atgaaggcat tgcccgaaat     1140

ctttcttgcc gggaaccaaa ccagcacttc aaaccttacc tgaaacattt cttacctaag     1200

cgtttgcact ttgctaagag tgatagaatt gagcccttga cattctattt ggaccctcag     1260

tggcaacttg cattgaatcc ctcagaaagg aaatattgtg gaagtggatt tcatggctct     1320

gacaatgtat tttcaaatat gcaagccctc tttgttggct atggacctgg attcaagcat     1380

ggcattgagg ctgacacctt tgaaaacatt gaagtctata acttaatgtg tgatttactg     1440

aatttgacac cggctcctaa taacggaact catggaagtc ttaaccacct tctaaagaat     1500

cctgtttata cgccaaagca tcccaaagaa gtgcaccccc tggtacagtg ccccttcaca     1560

agaaacccca gagataacct tggctgctca tgtaaccctt cgattttgcc gattgaggat     1620

tttcaaacac agttcaatct gactgtggca gaagagaaga ttattaagca tgaaacttta     1680

ccctatggaa gacctagagt tctccagaag gaaaacacca tctgtcttct ttcccagcac     1740

cagtttatga gtggatacag ccaagacatc ttaatgcccc tttggacatc ctataccgtg     1800

gacagaaatg acagtttctc tacggaagac ttctccaact gtctgtacca ggactttaga     1860

attcctctta gtcctgtcca taaatgttca ttttataaaa ataacaccaa agtgagttac     1920

gggttcctct ccccaccaca actaaataaa aattcaagtg gaatatattc tgaagctttg     1980

cttactacaa atatagtgcc aatgtaccag agttttcaag ttatatggcg ctactttcat     2040

gacaccctac tgcgaaagta tgctgaagaa agaaatggtg tcaatgtcgt cagtggtcct     2100

gtgtttgact ttgattatga tggacgttgt gattccttag agaatctgag gcaaaaaaga     2160

agagtcatcc gtaaccaaga aattttgatt ccaactcact tctttattgt gctaacaagc     2220

tgtaaagata catctcagac gcctttgcac tgtgaaaacc tagacacctt agctttcatt     2280

ttgcctcaca ggactgataa cagcgagagc tgtgtgcatg ggaagcatga ctcctcatgg     2340

gttgaagaat tgttaatgtt acacagagca cggatcacag atgttgagca catcactgga     2400

ctcagcttct atcaacaaag aaaagagcca gtttcagaca ttttaaagtt gaaaacacat     2460

ttgccaacct ttagccaaga agac                                            2484


<210>  3485
<211>  1020
<212>  DNA
<213>  Homo Sapiens

<400>  3485
atggaaagtg aagagttggc agacagggtt ctggatgtgg tggagaggag cctcagcaac       60

tacccctttg acttccaggg tgccaggatc attactggcc aagaggaagg tgcctatggc      120

tggattacta tcaactatct gctgggcaaa ttcagtcaga aaacaaggtg gttcagcata      180

gtcccatatg aaaccaataa tcaggaaacc tttggagctt tggaccttgg gggagcctct      240

acacaagtca cttttgtacc ccaaaaccag actatcgagt ccccagataa tgctctgcaa      300

tttcgcctct atggcaagga ctacaatgtc tacacacata gcttcttgtg ctatgggaag      360

gatcaggcac tctggcagaa actggccaag gacattcagg ttgcaagtaa tgaaattctc      420

agggacccat gctttcatcc tggatataag aaggtagtga acgtaagtga cctttacaag      480

accccctgca ccaagagatt tgagatgact cttccattcc agcagtttga aatccagggt      540

attggaaact atcaacaatg ccatcaaagc atcctggagc tcttcaacac cagttactgc      600

ccttactccc agtgtgcctt caatgggatt ttcttgccac cactccaggg ggattttggg      660

gcattttcag ctttttactt tgtgatgaag tttttaaact tgacatcaga gaaagtctct      720

caggaaaagg tgactgagat gatgaaaaag ttctgtgctc agccttggga ggagataaaa      780

acatcttacg ctggagtaaa ggagaagtac ctgagtgaat actgcttttc tggtacctac      840

attctctccc tccttctgca aggctatcat ttcacagctg attcctggga gcacatccat      900

ttcattggca agatccaggg cagcgacgcc ggctggactt tgggctacat gctgaacctg      960

accaacatga tcccagctga gcaaccattg tccacacctc tctcccactc cacctatgtc     1020


<210>  3486
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  3486
cagatccaca agcaagaggt cctccctcca ggactgaagt atggtattgt gctggatgcc       60

gggtcttcaa gaaccacagt ctacgtgtat caatggccag cagaaaaaga gaataatacc      120

ggagtggtca gtcaaacctt caaatgtagt gtgaaaggct ctggaatctc cagctatgga      180

aataaccccc aagatgtccc cagagccttt gaggagtgta tgcaaaaagt caaggggcag      240

gttccatccc acctccacgg atccaccccc attcacctgg gagccacggc tgggatgcgc      300

ttgctgaggt tgcaaaatga aacagcagct aatgaagtcc ttgaaagcat ccaaagctac      360

ttcaagtccc agccctttga ctttaggggt gctcaaatca tttctgggca agaagaaggg      420

gtatatggat ggattacagc caactattta atgggaaatt tcctggagaa gaacctgtgg      480

cacatgtggg tgcacccgca tggagtggaa accacgggtg ccctggactt aggtggtgcc      540

tccacccaaa tatccttcgt ggcaggagag aagatggatc tgaacaccag cgacatcatg      600

caggtgtccc tgtatggcta cgtatacacg ctctacacac acagcttcca gtgctatggc      660

cggaatgagg ctgagaagaa gtttctggca atgctcctgc agaattctcc taccaaaaac      720

catctcacca atccctgtta ccctcgggat tatagcatca gcttcaccat gggccatgta      780

tttgatagcc tgtgcactgt ggaccagagg ccagaaagtt ataaccccaa tgatgtcatc      840

acttttgaag gaactgggga cccatctctg tgtaaggaga aggtggcttc catatttgac      900

ttcaaagctt gccatgatca agaaacctgt tcttttgatg gggtttatca gccaaagatt      960

aaagggccat ttgtggcttt tgcaggattc tactacacag ccagtgcttt aaatctttca     1020

ggtagctttt ccctggacac cttcaactcc agcacctgga atttctgctc acagaattgg     1080

agtcagctcc cactgctgct ccccaaattt gatgaggtat atgcccgctc ttactgcttc     1140

tcagccaact acatctacca cttgtttgtg aacggttaca aattcacaga ggagacttgg     1200

ccccaaatac actttgaaaa agaagaa                                         1227


<210>  3487
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  3487
gcagccgtga ctgtaacacc tccaatcaca gcccagcaag ctgacaacat agaaggaccc       60

atagccttga agttctcaca cctttgcctg gaagatcata acagttactg catcaacggt      120

gcttgtgcat tccaccatga gctagagaaa gccatctgca ggtgttttac tggttatact      180

ggagaaaggt gtgagcactt gactttaact tcatatgctg tggattctta tgaaaaa         237


<210>  3488
<211>  1566
<212>  DNA
<213>  Homo Sapiens

<400>  3488
aaggaagtta ctctgatgga cacaagcaag gcacagggag agctgggctg gctgctggat       60

cccccaaaag atgggtggag tgaacagcaa cagatactga atgggacacc cctgtacatg      120

taccaggact gcccaatgca aggacgcaga gacactgacc actggcttcg ctccaattgg      180

atctaccgcg gggaggaggc ttcccgcgtc cacgtggagc tgcagttcac cgtgcgggac      240

tgcaagagtt tccctggggg agccgggcct ctgggctgca aggagacctt caaccttctg      300

tacatggaga gtgaccagga tgtgggcatt cagctccgac ggcccttgtt ccagaaggta      360

accacggtgg ctgcagacca gagcttcacc attcgagacc ttgcgtctgg ctccgtgaag      420

ctgaatgtgg agcgctgctc tctgggccgc ctgacccgcc gtggcctcta cctcgctttc      480

cacaacccgg gtgcctgtgt ggccctggtg tctgtccggg tcttctacca gcgctgtcct      540

gagaccctga atggcttggc ccaattccca gacactctgc ctggccccgc tgggttggtg      600

gaagtggcgg ggacctgctt gccccacgcg cgggccagcc ccaggccctc aggtgcaccc      660

cgcatgcact gcagccctga tggcgagtgg ctggtgcctg taggacggtg ccactgtgag      720

cctggctatg aggaaggtgg cagtggcgaa gcatgtgttg cctgccctag cggctcctac      780

cggatggaca tggacacacc ccattgtctc acgtgccccc agcagagcac tgctgagtct      840

gagggggcca ccatctgtac ctgtgagagc ggccattaca gagctcccgg ggagggcccc      900

caggtggcat gcacaggtcc cccctcggcc ccccgaaacc tgagcttctc tgcctcaggg      960

actcagctct ccctgcgttg ggaaccccca gcagatacgg ggggacgcca ggatgtcaga     1020

tacagtgtga ggtgttccca gtgtcagggc acagcacagg acggggggcc ctgccagccc     1080

tgtggggtgg gcgtgcactt ctcgccgggg gcccgggggc tcaccacacc tgcagtgcat     1140

gtcaatggcc ttgaacctta tgccaactac acctttaatg tggaagccca aaatggagtg     1200

tcagggctgg gcagctctgg ccatgccagc acctcagtca gcatcagcat ggggcatgca     1260

gagtcactgt caggcctgtc tctgagactg gtgaagaaag aaccgaggca actagagctg     1320

acctgggcgg ggtcccggcc ccgaagccct ggggcgaacc tgacctatga gctgcacgtg     1380

ctgaaccagg atgaagaacg gtaccagatg gttctagaac ccagggtctt gctgacagag     1440

ctgcagcctg acaccacata catcgtcaga gtccgaatgc tgaccccact gggtcctggc     1500

cctttctccc ctgatcatga gtttcggacc agcccaccag tgtccagggg cctgactgga     1560

ggagag                                                                1566


<210>  3489
<211>  1596
<212>  DNA
<213>  Homo Sapiens

<400>  3489
gaggaagtta tattattaga ttccaaagcc tctcaggcag agttagggtg gacggcactg       60

cctagtaatg gttgggaaga gatttctggg gttgacgagc acgacaggcc aattcgtacc      120

tatcaggtct gcaacgtctt agagcctaac caggacaact ggcttcagac tgggtggatc      180

agtcgtggaa gaggacaaag aatatttgtg gagctgcagt tcacactaag ggattgcagc      240

agcattccag gagctgcagg tacttgtaag gaaactttca acgtgtacta tttggaaact      300

gaagcggatt taggtagagg gcgtccaaga ctaggcggat ctcgtccccg taagattgat      360

actatcgctg ccgacgaatc ttttacgcag ggtgatttag gcgagagaaa gatgaaattg      420

aatacagaag ttagagagat cggcccgtta tctaggcgtg gtttccatct tgccttccag      480

gatgtggggg catgcgttgc acttgtcagc gtgagagtgt attacaagca gtgtagggcg      540

acagtcagag gccttgcgac atttcccgcc acagctgcgg aaagcgcctt cagtactctg      600

gttgaagtcg cgggaacttg cgtggcacat tcagagggtg agcctggcag tccaccgaga      660

atgcattgtg gcgccgacgg tgaatggttg gttccagttg gccgttgtag ctgttctgcc      720

ggattccagg aaagaggcga tttttgtgaa gcgtgtccgc cggggttcta taaggtcagt      780

ccgagaaggc cattgtgttc cccctgccca gagcatagca gagcgttaga gaacgcaagt      840

accttctgtg tgtgtcagga ttcttacgct cgttctccca cagacccacc gagtgcatct      900

tgtacaagac cgccttcagc accgagagac ttacagtaca gtttgagccg tagtccgcta      960

gtgctacgtc ttagatggct tccccctgcg gatagcggtg gtaggtctga cgtcacatac     1020

tctctactgt gcctgagatg cggtagagag ggtcctgcgg gggcttgcga gccttgcggc     1080

ccccgtgtcg catttttacc caggcaagcg ggtctaagag agagagcagc cacgctgttg     1140

catcttagac ccggggctcg ttatacggtg agggtcgcgg cgttaaatgg tgtatccggc     1200

cccgctgcgg cagccggcac tacttacgcg caagtaaccg tatcaacggg cccgggagca     1260

ccttgggaag aagatgagat aagaagggac agggtggagc ctcaatctgt gagcctgtca     1320

tggcgtgaac caatcccggc gggagccccc ggggcaaatg atactgaata cgagattcgt     1380

tactacgaga agggacaatc tgaacaaact tacagtatgg ttaaaaccgg tgctcctaca     1440

gtgacagtaa cgaatttgaa gcccgcaact aggtatgtgt ttcaaattag agccgcgtcc     1500

ccgggcccaa gttgggaagc ccagtccttt aatccctcca tcgaggtaca aacccttgga     1560

gaggccgcgt ctgggagccg tgaccagtca cctgcc                               1596


<210>  3490
<211>  1542
<212>  DNA
<213>  Homo Sapiens

<400>  3490
gcgcagggca aggaagtggt actgctggac tttgctgcag ctggagggga gctcggctgg       60

ctcacacacc cgtatggcaa agggtgggac ctgatgcaga acatcatgaa tgacatgccg      120

atctacatgt actccgtgtg caacgtgatg tctggcgacc aggacaactg gctccgcacc      180

aactgggtgt accgaggaga ggctgagcgt atcttcattg agctcaagtt tactgtacgt      240

gactgcaaca gcttccctgg tggcgccagc tcctgcaagg agactttcaa cctctactat      300

gccgagtcgg acctggacta cggcaccaac ttccagaagc gcctgttcac caagattgac      360

accattgcgc ccgatgagat caccgtcagc agcgacttcg aggcacgcca cgtgaagctg      420

aacgtggagg agcgctccgt ggggccgctc acccgcaaag gcttctacct ggccttccag      480

gatatcggtg cctgtgtggc gctgctctcc gtccgtgtct actacaagaa gtgccccgag      540

ctgctgcagg gcctggccca cttccctgag accatcgccg gctctgatgc accttccctg      600

gccactgtgg ccggcacctg tgtggaccat gccgtggtgc caccgggggg tgaagagccc      660

cgtatgcact gtgcagtgga tggcgagtgg ctggtgccca ttgggcagtg cctgtgccag      720

gcaggctacg agaaggtgga ggatgcctgc caggcctgct cgcctggatt ttttaagttt      780

gaggcatctg agagcccctg cttggagtgc cctgagcaca cgctgccatc ccctgagggt      840

gccacctcct gcgagtgtga ggaaggcttc ttccgggcac ctcaggaccc agcgtcgatg      900

ccttgcacac gacccccctc cgccccacac tacctcacag ccgtgggcat gggtgccaag      960

gtggagctgc gctggacgcc ccctcaggac agcgggggcc gcgaggacat tgtctacagc     1020

gtcacctgcg aacagtgctg gcccgagtct ggggaatgcg ggccgtgtga ggccagtgtg     1080

cgctactcgg agcctcctca cggactgacc cgcaccagtg tgacagtgag cgacctggag     1140

ccccacatga actacacctt caccgtggag gcccgcaatg gcgtctcagg cctggtaacc     1200

agccgcagct tccgtactgc cagtgtcagc atcaaccaga cagagccccc caaggtgagg     1260

ctggagggcc gcagcaccac ctcgcttagc gtctcctgga gcatcccccc gccgcagcag     1320

agccgagtgt ggaagtacga ggtcacttac cgcaagaagg gagactccaa cagctacaat     1380

gtgcgccgca ccgagggttt ctccgtgacc ctggacgacc tggccccaga caccacctac     1440

ctggtccagg tgcaggcact gacgcaggag ggccaggggg ccggcagcaa ggtgcacgaa     1500

ttccagacgc tgtccccgga gggatctggc aacttggcgg tg                        1542


<210>  3491
<211>  1563
<212>  DNA
<213>  Homo Sapiens

<400>  3491
gaactgattc cgcagccttc caatgaagtc aatctactgg attcaaaaac aattcaaggg       60

gagctgggct ggatctctta tccatcacat gggtgggaag agatcagtgg tgtggatgaa      120

cattacacac ccatcaggac ttaccaggtg tgcaatgtca tggaccacag tcaaaacaat      180

tggctgagaa caaactgggt ccccaggaac tcagctcaga agatttatgt ggagctcaag      240

ttcactctac gagactgcaa tagcattcca ttggttttag gaacttgcaa ggagacattc      300

aacctgtact acatggagtc tgatgatgat catggggtga aatttcgaga gcatcagttt      360

acaaagattg acaccattgc agctgatgaa agtttcactc aaatggatct tggggaccgt      420

attctgaagc tcaacactga gattagagaa gtaggtcctg tcaacaagaa gggattttat      480

ttggcatttc aagatgttgg tgcttgtgtt gccttggtgt ctgtgagagt atacttcaaa      540

aagtgcccat ttacagtgaa gaatctggct atgtttccag acacggtacc catggactcc      600

cagtccctgg tggaggttag agggtcttgt gtcaacaatt ctaaggagga agatcctcca      660

aggatgtact gcagtacaga aggcgaatgg cttgtaccca ttggcaagtg ttcctgcaat      720

gctggctatg aagaaagagg ttttatgtgc caagcttgtc gaccaggttt ctacaaggca      780

ttggatggta atatgaagtg tgctaagtgc ccgcctcaca gttctactca ggaagatggt      840

tcaatgaact gcaggtgtga gaataattac ttccgggcag acaaagaccc tccatccatg      900

gcttgtaccc gacctccatc ttcaccaaga aatgttatct ctaatataaa cgagacctca      960

gttatcctgg actggagttg gcccctggac acaggaggcc ggaaagatgt taccttcaac     1020

atcatatgta aaaaatgtgg gtggaatata aaacagtgtg agccatgcag cccaaatgtc     1080

cgcttcctcc ctcgacagtt tggactcacc aacaccacgg tgacagtgac agaccttctg     1140

gcacatacta actacacctt tgagattgat gccgttaatg gggtgtcaga gctgagctcc     1200

ccaccaagac agtttgctgc ggtcagcatc acaactaatc aggctgctcc atcacctgtc     1260

ctgacgatta agaaagatcg gacctccaga aatagcatct ctttgtcctg gcaagaacct     1320

gaacatccta atgggatcat attggactac gaggtcaaat actatgaaaa gcaggaacaa     1380

gaaacaagtt ataccattct gagggcaaga ggcacaaatg ttaccatcag tagcctcaag     1440

cctgacacta tatacgtatt ccaaatccga gcccgaacag ccgctggata tgggacgaac     1500

agccgcaagt ttgagtttga aactagtcca gactctttct ccatctctgg tgaaagtagc     1560

caa                                                                   1563


<210>  3492
<211>  1584
<212>  DNA
<213>  Homo Sapiens

<400>  3492
gtcacaggtt ccagggtata ccccgcgaat gaagttacct tattggattc cagatctgtt       60

cagggagaac ttgggtggat agcaagccct ctggaaggag ggtgggagga agtgagtatc      120

atggatgaaa aaaatacacc aatccgaacc taccaagtgt gcaatgtgat ggaacccagc      180

cagaataact ggctacgaac tgattggatc acccgagaag gggctcagag ggtgtatatt      240

gagattaaat tcaccttgag ggactgcaat agtcttccgg gcgtcatggg gacttgcaag      300

gagacgttta acctgtacta ctatgaatca gacaacgaca aagagcgttt catcagagag      360

aaccagtttg tcaaaattga caccattgct gctgatgaga gcttcaccca agtggacatt      420

ggtgacagaa tcatgaagct gaacaccgag atccgggatg tagggccatt aagcaaaaag      480

gggttttacc tggcttttca ggatgtgggg gcctgcatcg ccctggtatc agtccgtgtg      540

ttctataaaa agtgtccact cacagtccgc aatctggccc agtttcctga caccatcaca      600

ggggctgata cgtcttccct ggtggaagtt cgaggctcct gtgtcaacaa ctcagaagag      660

aaagatgtgc caaaaatgta ctgtggggca gatggtgaat ggctggtacc cattggcaac      720

tgcctatgca acgctgggca tgaggagcgg agcggagaat gccaagcttg caaaattgga      780

tattacaagg ctctctccac ggatgccacc tgtgccaagt gcccacccca cagctactct      840

gtctgggaag gagccacctc gtgcacctgt gaccgaggct ttttcagagc tgacaacgat      900

gctgcctcta tgccctgcac ccgtccacca tctgctcccc tgaacttgat ttcaaatgtc      960

aacgagacat ctgtgaactt ggaatggagt agccctcaga atacaggtgg ccgccaggac     1020

atttcctata atgtggtatg caagaaatgt ggagctggtg accccagcaa gtgccgacca     1080

tgtggaagtg gggtccacta caccccacag cagaatggct tgaagaccac caaagtctcc     1140

atcactgacc tcctagctca taccaattac acctttgaaa tctgggctgt gaatggagtg     1200

tccaaatata accctaaccc agaccaatca gtttctgtca ctgtgaccac caaccaagca     1260

gcaccatcat ccattgcttt ggtccaggct aaagaagtca caagatacag tgtggcactg     1320

gcttggctgg aaccagatcg gcccaatggg gtaatcctgg aatatgaagt caagtattat     1380

gagaaggatc agaatgagcg aagctatcgt atagttcgga cagctgccag gaacacagat     1440

atcaaaggcc tgaaccctct cacttcctat gttttccacg tgcgagccag gacagcagct     1500

ggctatggag acttcagtga gcccttggag gttacaacca acacagtgcc ttcccggatc     1560

attggagatg gggctaactc caca                                            1584


<210>  3493
<211>  1650
<212>  DNA
<213>  Homo Sapiens

<400>  3493
ccagcgtccc tggccggctg ctactctgca cctcgacggg ctcccctctg gacgtgcctt       60

ctcctgtgcg ccgcactccg gaccctcctg gccagcccca gcaatgaagt gaatttattg      120

gattcacgca ctgtcatggg ggacctggga tggattgctt ttccaaaaaa tgggtgggaa      180

gagattggtg aagtggatga aaattatgcc cctatccaca cataccaagt atgcaaagtg      240

atggaacaga atcagaataa ctggcttttg accagttgga tctccaatga aggtgcttcc      300

agaatcttca tagaactcaa atttaccctg cgggactgca acagccttcc tggaggactg      360

gggacctgta aggaaacctt taatatgtat tactttgagt cagatgatca gaatgggaga      420

aacatcaagg aaaaccaata catcaaaatt gataccattg ctgccgatga aagctttaca      480

gaacttgatc ttggtgaccg tgttatgaaa ctgaatacag aggtcagaga tgtaggacct      540

ctaagcaaaa agggatttta tcttgctttt caagatgttg gtgcttgcat tgctctggtt      600

tctgtgcgtg tatactataa aaaatgccct tctgtggtac gacacttggc tgtcttccct      660

gacaccatca ctggagctga ttcttcccaa ttgctcgaag tgtcaggctc ctgtgtcaac      720

cattctgtga ccgatgaacc tcccaaaatg cactgcagcg ccgaagggga gtggctggtg      780

cccatcggga aatgcatgtg caaggcagga tatgaagaga aaaatggcac ctgtcaagtg      840

tgcagacctg ggttcttcaa agcctcacct cacatccaga gctgcggcaa atgtccacct      900

cacagttata cccatgagga agcttcaacc tcttgtgtct gtgaaaagga ttatttcagg      960

agagagtctg atccacccac aatggcatgc acaagacccc cctctgctcc tcggaatgcc     1020

atctcaaatg ttaatgaaac tagtgtcttt ctggaatgga ttccgcctgc tgacactggt     1080

ggaaggaaag acgtgtcata ttatattgca tgcaagaagt gcaactccca tgcaggtgtg     1140

tgtgaggagt gtggcggtca tgtcaggtac cttccccggc aaagcggcct gaaaaacacc     1200

tctgtcatga tggtggatct actcgctcac acaaactata cctttgagat tgaggcagtg     1260

aatggagtgt ccgacttgag cccaggagcc cggcagtatg tgtctgtaaa tgtaaccaca     1320

aatcaagcag ctccatctcc agtcaccaat gtgaaaaaag ggaaaattgc aaaaaacagc     1380

atctctttgt cttggcaaga accagatcgt cccaatggaa tcatcctaga gtatgaaatc     1440

aagtattttg aaaaggacca agagaccagc tacacgatta tcaaatctaa agagacaact     1500

attactgcag agggcttgaa accagcttca gtttatgtct tccaaattcg agcacgtaca     1560

gcagcaggct atggtgtctt cagtcgaaga tttgagtttg aaaccacccc agtgtcagtt     1620

gcagcatcca gcgatcaaag ccagattcct                                      1650


<210>  3494
<211>  108
<212>  DNA
<213>  Homo Sapiens

<400>  3494
atgaaagact ctccatttca agtgacaaaa ctgtactggc ttaatgaaaa gtgggacttt       60

attgcctcag cttctgacat ggcagcagaa caaggacaga ttctcgtg                   108


<210>  3495
<211>  1584
<212>  DNA
<213>  Homo Sapiens

<400>  3495
caggctgcga aggaagtact actgctggat tctaaagcac aacaaacaga gttggagtgg       60

atttcctctc cacccaatgg gtgggaagaa attagtggtt tggatgagaa ctataccccg      120

atacgaacat accaggtgtg ccaagtcatg gagcccaacc aaaacaactg gctgcggact      180

aactggattt ccaaaggcaa tgcacaaagg atttttgtag aattgaaatt caccctgagg      240

gattgtaaca gtcttcctgg agtactggga acttgcaagg aaacatttaa tttgtactat      300

tatgaaacag actatgacac tggcaggaat ataagagaaa acctctatgt aaaaatagac      360

accattgctg cagatgaaag ttttacccaa ggtgaccttg gtgaaagaaa gatgaagctt      420

aacactgagg tgagagagat tggacctttg tccaaaaagg gattctatct tgcctttcag      480

gatgtagggg cttgcatagc tttggtttct gtcaaagtgt actacaagaa gtgctggtcc      540

attattgaga acttagctat ctttccagat acagtgactg gttcagaatt ttcctcttta      600

gtcgaggttc gagggacatg tgtcagcagt gcagaggaag aagcggaaaa cgcccccagg      660

atgcactgca gtgcagaagg agaatggtta gtgcccattg gaaaatgtat ctgcaaagca      720

ggctaccagc aaaaaggaga cacttgtgaa ccctgtggcc gtgggttcta caagtcttcc      780

tctcaagatc ttcagtgctc tcgttgtcca actcacagtt tttctgataa agaaggctcc      840

tccagatgtg aatgtgaaga tgggtattac agggctccat ctgacccacc atacgttgca      900

tgcacaaggc ctccatctgc accacagaac ctcattttca acatcaacca aaccacagta      960

agtttggaat ggagtcctcc tgcagacaat gggggaagaa acgatgtgac ctacagaata     1020

ttgtgtaagc ggtgcagttg ggagcagggc gaatgtgttc cctgtgggag taacattgga     1080

tacatgcccc agcagactgg attagaggat aactatgtca ctgtcatgga cctgctagcc     1140

cacgctaatt atacttttga agttgaagct gtaaatggag tttctgactt aagccgatcc     1200

cagaggctct ttgctgctgt cagtatcacc actggtcaag cagctccctc gcaagtgagc     1260

ggagtaatga aggagagagt actgcagcgg agtgtcgagc tttcctggca ggaaccagag     1320

catcccaatg gagtcatcac agaatatgaa atcaagtatt acgagaaaga tcaaagggaa     1380

cggacctact caacagtaaa aaccaagtct acttcagcct ccattaataa tctgaaacca     1440

ggaacagtgt atgttttcca gattcgggct tttactgctg ctggttatgg aaattacagt     1500

cccagacttg atgttgctac actagaggaa gctacaggta aaatgtttga agctacagct     1560

gtctccagtg aacagaatcc tgtt                                            1584


<210>  3496
<211>  1545
<212>  DNA
<213>  Homo Sapiens

<400>  3496
gcgcgcggcg aagtgaattt gctggacacg tcgaccatcc acggggactg gggctggctc       60

acgtatccgg ctcatgggtg ggactccatc aacgaggtgg acgagtcctt ccagcccatc      120

cacacgtacc aggtttgcaa cgtcatgagc cccaaccaga acaactggct gcgcacgagc      180

tgggtccccc gagacggcgc ccggcgcgtc tatgctgaga tcaagtttac cctgcgcgac      240

tgcaacagca tgcctggtgt gctgggcacc tgcaaggaga ccttcaacct ctactacctg      300

gagtcggacc gcgacctggg ggccagcaca caagaaagcc agttcctcaa aatcgacacc      360

attgcggccg acgagagctt cacaggtgcc gaccttggtg tgcggcgtct caagctcaac      420

acggaggtgc gcagtgtggg tcccctcagc aagcgcggct tctacctggc cttccaggac      480

ataggtgcct gcctggccat cctctctctc cgcatctact ataagaagtg ccctgccatg      540

gtgcgcaatc tggctgcctt ctcggaggca gtgacggggg ccgactcgtc ctcactggtg      600

gaggtgaggg gccagtgcgt gcggcactca gaggagcggg acacacccaa gatgtactgc      660

agcgcggagg gcgagtggct cgtgcccatc ggcaaatgcg tgtgcagtgc cggctacgag      720

gagcggcggg atgcctgtgt ggcctgtgag ctgggcttct acaagtcagc ccctggggac      780

cagctgtgtg cccgctgccc tccccacagc cactccgcag ctccagccgc ccaagcctgc      840

cactgtgacc tcagctacta ccgtgcagcc ctggacccgc cgtcctcagc ctgcacccgg      900

ccaccctcgg caccagtgaa cctgatctcc agtgtgaatg ggacatcagt gactctggag      960

tgggcccctc ccctggaccc aggtggccgc agtgacatca cctacaatgc cgtgtgccgc     1020

cgctgcccct gggcactgag ccgctgcgag gcatgtggga gcggcacccg ctttgtgccc     1080

cagcagacaa gcctggtgca ggccagcctg ctggtggcca acctgctggc ccacatgaac     1140

tactccttct ggatcgaggc cgtcaatggc gtgtccgacc tgagccccga gccccgccgg     1200

gccgctgtgg tcaacatcac cacgaaccag gcagccccgt cccaggtggt ggtgatccgt     1260

caagagcggg cggggcagac cagcgtctcg ctgctgtggc aggagcccga gcagccgaac     1320

ggcatcatcc tggagtatga gatcaagtac tacgagaagg acaaggagat gcagagctac     1380

tccaccctca aggccgtcac caccagagcc accgtctccg gcctcaagcc gggcacccgc     1440

tacgtgttcc aggtccgagc ccgcacctca gcaggctgtg gccgcttcag ccaggccatg     1500

gaggtggaga ccgggaaacc ccggccccgc tatgacacca ggacc                     1545


<210>  3497
<211>  1569
<212>  DNA
<213>  Homo Sapiens

<400>  3497
atggaagaaa cgttaatgga caccagaacg gctactgcag agctgggctg gacggccaat       60

cctgcgtccg ggtgggaaga agtcagtggc tacgatgaaa acctgaacac catccgcacc      120

taccaggtgt gcaatgtctt cgagcccaac cagaacaatt ggctgctcac caccttcatc      180

aaccggcggg gggcccatcg catctacaca gagatgcgct tcactgtgag agactgcagc      240

agcctcccta atgtcccagg atcctgcaag gagaccttca acttgtatta ctatgagact      300

gactctgtca ttgccaccaa gaagtcagcc ttctggtctg aggcccccta cctcaaagta      360

gacaccattg ctgcagatga gagcttctcc caggtggact ttgggggaag gctgatgaag      420

gtaaacacag aagtcaggag ctttgggcct cttactcgga atggttttta cctcgctttt      480

caggattatg gagcctgtat gtctcttctt tctgtccgtg tcttcttcaa aaagtgtccc      540

agcattgtgc aaaattttgc agtgtttcca gagactatga caggggcaga gagcacatct      600

ctggtgattg ctcggggcac atgcatcccc aacgcagagg aagtggacgt gcccatcaaa      660

ctctactgca acggggatgg ggaatggatg gtgcctattg ggcgatgcac ctgcaagcct      720

ggctatgagc ctgagaacag cgtggcatgc aaggcttgcc ctgcagggac attcaaggcc      780

agccaggaag ctgaaggctg ctcccactgc ccctccaaca gccgctcccc tgcagaggcg      840

tctcccatct gcacctgtcg gaccggttat taccgagcgg actttgaccc tccagaagtg      900

gcatgcacta gcgtcccatc aggtccccgc aatgttatct ccatcgtcaa tgagacgtcc      960

atcattctgg agtggcaccc tccaagggag acaggtgggc gggatgatgt gacctacaac     1020

atcatctgca aaaagtgccg ggcagaccgc cggagctgct cccgctgtga cgacaatgtg     1080

gagtttgtgc ccaggcagct gggcctgacg gagtgccgcg tctccatcag cagcctgtgg     1140

gcccacaccc cctacacctt tgacatccag gccatcaatg gagtctccag caagagtccc     1200

ttccccccac agcacgtctc tgtcaacatc accacaaacc aagccgcccc ctccaccgtt     1260

cccatcatgc accaagtcag tgccactatg aggagcatca ccttgtcatg gccacagccg     1320

gagcagccca atggcatcat cctggactat gagatccggt actatgagaa ggaacacaat     1380

gagttcaact cctccatggc caggagtcag accaacacag caaggattga tgggctgcgg     1440

cctggcatgg tatatgtggt acaggtgcgt gcccgcactg ttgctggcta cggcaagttc     1500

agtggcaaga tgtgcttcca gactctgact gacgatgatt acaagtcaga gctgagggag     1560

cagctgccc                                                             1569


<210>  3498
<211>  1575
<212>  DNA
<213>  Homo Sapiens

<400>  3498
gtggaagaaa cgctaatgga ctccactaca gcgactgctg agctgggctg gatggtgcat       60

cctccatcag ggtgggaaga ggtgagtggc tacgatgaga acatgaacac gatccgcacg      120

taccaggtgt gcaacgtgtt tgagtcaagc cagaacaact ggctacggac caagtttatc      180

cggcgccgtg gcgcccaccg catccacgtg gagatgaagt tttcggtgcg tgactgcagc      240

agcatcccca gcgtgcctgg ctcctgcaag gagaccttca acctctatta ctatgaggct      300

gactttgact cggccaccaa gaccttcccc aactggatgg agaatccatg ggtgaaggtg      360

gataccattg cagccgacga gagcttctcc caggtggacc tgggtggccg cgtcatgaaa      420

atcaacaccg aggtgcggag cttcggacct gtgtcccgca gcggcttcta cctggccttc      480

caggactatg gcggctgcat gtccctcatc gccgtgcgtg tcttctaccg caagtgcccc      540

cgcatcatcc agaatggcgc catcttccag gaaaccctgt cgggggctga gagcacatcg      600

ctggtggctg cccggggcag ctgcatcgcc aatgcggaag aggtggatgt acccatcaag      660

ctctactgta acggggacgg cgagtggctg gtgcccatcg ggcgctgcat gtgcaaagca      720

ggcttcgagg ccgttgagaa tggcaccgtc tgccgaggtt gtccatctgg gactttcaag      780

gccaaccaag gggatgaggc ctgtacccac tgtcccatca acagccggac cacttctgaa      840

ggggccacca actgtgtctg ccgcaatggc tactacagag cagacctgga ccccctggac      900

atgccctgca caaccatccc ctccgcgccc caggctgtga tttccagtgt caatgagacc      960

tccctcatgc tggagtggac ccctccccgc gactccggag gccgagagga cctcgtctac     1020

aacatcatct gcaagagctg tggctcgggc cggggtgcct gcacccgctg cggggacaat     1080

gtacagtacg caccacgcca gctaggcctg accgagccac gcatttacat cagtgacctg     1140

ctggcccaca cccagtacac cttcgagatc caggctgtga acggcgttac tgaccagagc     1200

cccttctcgc ctcagttcgc ctctgtgaac atcaccacca accaggcagc tccatcggca     1260

gtgtccatca tgcatcaggt gagccgcacc gtggacagca ttaccctgtc gtggtcccag     1320

ccggaccagc ccaatggcgt gatcctggac tatgagctgc agtactatga gaaggagctc     1380

agtgagtaca acgccacagc cataaaaagc cccaccaaca cggtcaccgt gcagggcctc     1440

aaagccggcg ccatctatgt cttccaggtg cgggcacgca ccgtggcagg ctacgggcgc     1500

tacagcggca agatgtactt ccagaccatg acagaagccg agtaccagac aagcatccag     1560

gagaagttgc cactc                                                      1575


<210>  3499
<211>  1578
<212>  DNA
<213>  Homo Sapiens

<400>  3499
ggctgccggg cgctggaaga gaccctcatg gacacaaaat gggtaacatc tgagttggcg       60

tggacatctc atccagaaag tgggtgggaa gaggtgagtg gctacgatga ggccatgaat      120

cccatccgca cataccaggt gtgtaatgtg cgcgagtcaa gccagaacaa ctggcttcgc      180

acggggttca tctggcggcg ggatgtgcag cgggtctacg tggagctcaa gttcactgtg      240

cgtgactgca acagcatccc caacatcccc ggctcctgca aggagacctt caacctcttc      300

tactacgagg ctgacagcga tgtggcctca gcctcctccc ccttctggat ggagaacccc      360

tacgtgaaag tggacaccat tgcacccgat gagagcttct cgcggctgga tgccggccgt      420

gtcaacacca aggtgcgcag ctttgggcca ctttccaagg ctggcttcta cctggccttc      480

caggaccagg gcgcctgcat gtcgctcatc tccgtgcgcg ccttctacaa gaagtgtgca      540

tccaccaccg caggcttcgc actcttcccc gagaccctca ctggggcgga gcccacctcg      600

ctggtcattg ctcctggcac ctgcatccct aacgccgtgg aggtgtcggt gccactcaag      660

ctctactgca acggcgatgg ggagtggatg gtgcctgtgg gtgcctgcac ctgtgccacc      720

ggccatgagc cagctgccaa ggagtcccag tgccgcccct gtccccctgg gagctacaag      780

gcgaagcagg gagaggggcc ctgcctccca tgtcccccca acagccgtac cacctcccca      840

gccgccagca tctgcacctg ccacaataac ttctaccgtg cagactcgga ctctgcggac      900

agtgcctgta ccaccgtgcc atctccaccc cgaggtgtga tctccaatgt gaatgaaacc      960

tcactgatcc tcgagtggag tgagccccgg gacctgggtg gccgggatga cctcctgtac     1020

aatgtcatct gcaagaagtg ccatggggct ggaggggcct cagcctgctc acgctgtgat     1080

gacaacgtgg agtttgtgcc tcggcagctg ggcctgacgg agcgccgggt ccacatcagc     1140

catctgctgg cccacacgcg ctacaccttt gaggtgcagg cggtcaacgg tgtctcgggc     1200

aagagccctc tgccgcctcg ttatgcggcc gtgaatatca ccacaaacca ggctgccccg     1260

tctgaagtgc ccacactacg cctgcacagc agctcaggca gcagcctcac cctatcctgg     1320

gcacccccag agcggcccaa cggagtcatc ctggactacg agatgaagta ctttgagaag     1380

agcgagggca tcgcctccac agtgaccagc cagatgaact ccgtgcagct ggacgggctt     1440

cggcctgacg cccgctatgt ggtccaggtc cgtgcccgca cagtagctgg ctatgggcag     1500

tacagccgcc ctgccgagtt tgagaccaca agtgagagag gctctggggc ccagcagctc     1560

caggagcagc ttcccctc                                                   1578


<210>  3500
<211>  1572
<212>  DNA
<213>  Homo Sapiens

<400>  3500
ttggaagaga ccctgctgaa cacaaaattg gaaactgctg atctgaagtg ggtgacattc       60

cctcaggtgg acgggcagtg ggaggaactg agcggcctgg atgaggaaca gcacagcgtg      120

cgcacctacg aagtgtgtga cgtgcagcgt gccccgggcc aggcccactg gcttcgcaca      180

ggttgggtcc cacggcgggg cgccgtccac gtgtacgcca cgctgcgctt caccatgctc      240

gagtgcctgt ccctgcctcg ggctgggcgc tcctgcaagg agaccttcac cgtcttctac      300

tatgagagcg atgcggacac ggccacggcc ctcacgccag cctggatgga gaacccctac      360

atcaaggtgg acacggtggc cgcggagcat ctcacccgga agcgccctgg ggccgaggcc      420

accgggaagg tgaatgtcag gacgctgcgt ctgggaccgc tcagcaaggc tggcttctac      480

ctggccttcc aggaccaggg tgcctgcatg gccctgctat ccctgcacct cttctacaaa      540

aagtgcgccc agctgactgt gaacctgact cgattcccgg agactgtgcc tcgggagctg      600

gttgtgcccg tggccggtag ctgcgtggtg gatgccgtcc ccgcccctgg ccccagcccc      660

agcctctact gccgtgagga tggccagtgg gccgaacagc cggtcacggg ctgcagctgt      720

gctccggggt tcgaggcagc tgaggggaac accaagtgcc gagcctgtgc ccagggcacc      780

ttcaagcccc tgtcaggaga agggtcctgc cagccatgcc cagccaatag ccactctaac      840

accattggat cagccgtctg ccagtgccgc gtcgggtact tccgggcacg cacagacccc      900

cggggtgcac cctgcaccac ccctccttcg gctccgcgga gcgtggtttc ccgcctgaac      960

ggctcctccc tgcacctgga atggagtgcc cccctggagt ctggtggccg agaggacctc     1020

acctacgccc tccgctgccg ggagtgccga cccggaggct cctgtgcgcc ctgcggggga     1080

gacctgactt ttgaccccgg cccccgggac ctggtggagc cctgggtggt ggttcgaggg     1140

ctacgtcctg acttcaccta tacctttgag gtcactgcat tgaacggggt atcctcctta     1200

gccacggggc ccgtcccatt tgagcctgtc aatgtcacca ctgaccgaga ggtacctcct     1260

gcagtgtccg acatccgggt gacgcggtcc tcacccagca gcttgagcct ggcctgggct     1320

gttccccggg cacccagtgg ggctgtgctg gactacgagg tcaaatacca tgagaagggc     1380

gccgagggtc ccagcagcgt gcggttcctg aagacgtcag aaaaccgggc agagctgcgg     1440

gggctgaagc ggggagccag ctacctggtg caggtacggg cgcgctctga ggccggctac     1500

gggcccttcg gccaggaaca tcacagccag acccaactgg atgagagcga gggctggcgg     1560

gagcagctgg cc                                                         1572


<210>  3501
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  3501
cctccatcgg ctccccagga gctttggttt gaggtgcaag gctcagcact catgctacac       60

tggcgcctgc ctcgggagct ggggggtcga ggggacctgc tcttcaatgt cgtgtgcaag      120

gagtgtgaag gccgccagga acctgccagc ggtggtgggg gcacttgtca ccgctgcagg      180

gatgaggtcc acttcgaccc tcgccagaga ggcctgactg agagccgagt gttagtgggg      240

ggactccggg cacacgtacc ctacatctta gaggtgcagg ctgttaatgg ggtgtctgag      300

ctcagccctg accctcctca ggctgcagcc atcaatgtca gcaccagcca tgaagtgccc      360

tctgctgtcc ctgtggtgca ccaggtgagc cgggcatcca acagcatcac ggtgtcctgg      420

ccgcagcccg accagaccaa tgggaacatc ctggactatc agctccgcta ctatgaccag      480

gcagaagacg aatcccactc cttcaccctg accagcgaga ccaacactgc caccgtgaca      540

cagctgagcc ctggccacat ctatggtttc caggtgcggg cccggactgc tgccggccac      600

ggcccctacg ggggcaaagt ctatttccag acacttcctc aaggggagct gtcttcccag      660

cttccggaaa gactctcc                                                    678


<210>  3502
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3502
gccccaccac gcctcatctg tgacagccga gtcctggaga ggtacctctt ggaggccaag       60

gaggccgaga atatcacgac gggctgtgct gaacactgca gcttgaatga gaatatcact      120

gtcccagaca ccaaagttaa tttctatgcc tggaagagga tggaggtcgg gcagcaggcc      180

gtagaagtct ggcagggcct ggccctgctg tcggaagctg tcctgcgggg ccaggccctg      240

ttggtcaact cttcccagcc gtgggagccc ctgcagctgc atgtggataa agccgtcagt      300

ggccttcgca gcctcaccac tctgcttcgg gctctgggag cccagaagga agccatctcc      360

cctccagatg cggcctcagc tgctccactc cgaacaatca ctgctgacac tttccgcaaa      420

ctcttccgag tctactccaa tttcctccgg ggaaagctga agctgtacac aggggaggcc      480

tgcaggacag gggacaga                                                    498


<210>  3503
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  3503
gctccgccgc caaatttgcc agaccccaag ttcgagtcaa aagcggcctt actagccgcc       60

cgtggccccg aagagttatt atgtttcact gagcgtctgg aggatctggt ttgcttttgg      120

gaggaggcag cctccgctgg tgtaggacca ggaaactact ccttcagtta tcagttggag      180

gacgaaccgt ggaaactgtg caggctgcat caagctccaa cggctagagg tgcggtacgt      240

ttttggtgca gtcttccgac ggctgatacg agttcattcg tcccgcttga acttagggta      300

actgccgcct caggggctcc ccgttatcac agggtcattc atatcaacga agttgttttg      360

ttggacgcac cagtcggttt agtagctagg ttggcagatg aaagtggcca tgtcgtgcta      420

aggtggcttc ctcctcctga aacccccatg acaagccaca taaggtatga agtagacgtg      480

agcgcgggga atggggcggg gtctgtccaa agggttgaaa tacttgaagg tagaaccgaa      540

tgcgtattgt ctaatttgcg tgggaggaca agatacacat ttgccgtacg tgccaggatg      600

gcagagcctt cctttggtgg cttttggtca gcatggagcg agccggtcag tctgctgacc      660

ccatctgacc tggacccg                                                    678


<210>  3504
<211>  909
<212>  DNA
<213>  Homo Sapiens

<400>  3504
gccccaactc tagagtccat caactatgac tcagaaacct atgatgccac cttagaagac       60

ctggataatt tgtacaacta tgaaaacata cctgttggta aagttgagat tgaaatagcc      120

acagtgatgc cttcagggaa cagagagctc ctcactccac ccccacagcc tgagaaggcc      180

caggaagagg aagaggagga ggaatctact cccaggctga ttgatggctc ttctccccag      240

gagcctgaat tcacaggggt tctggggcca cacacaaatg aagactttcc aacctgtctt      300

ttgtgtactt gtataagtac caccgtgtac tgtgatgacc atgaacttga tgctattcct      360

ccgctgccaa agaacaccgc ttatttctat tcccgcttta acagaattaa aaagatcaac      420

aaaaatgact ttgcaagcct aagtgattta aaaaggattg atctgacatc aaatttaata      480

tctgagattg atgaagatgc attccgaaaa ctgcctcaac ttcgagagct tgtcctgcgt      540

gacaacaaaa taaggcagct cccagaattg ccaaccactt tgacatttat tgatattagc      600

aacaatagac ttggaaggaa agggataaag caagaagcat ttaaagacat gtatgatctc      660

catcatctgt acctcactga taacaacttg gaccacatcc ctctgccact cccagaaaat      720

ctacgagccc ttcacctcca gaataacaac attctggaaa tgcacgaaga tacgttctgc      780

aatgttaaaa atttgactta tattcgtaag gcactagagg acattcgatt ggatggaaac      840

cctattaatc tcagcaaaac tcctcaagca tacatgtgtc tacctcgtct gcctgttggg      900

agccttgtc                                                              909


<210>  3505
<211>  1890
<212>  DNA
<213>  Homo Sapiens

<400>  3505
acccaagtgt gcaccggcac agacatgaag ctgcggctcc ctgccagtcc cgagacccac       60

ctggacatgc tccgccacct ctaccagggc tgccaggtgg tgcagggaaa cctggaactc      120

acctacctgc ccaccaatgc cagcctgtcc ttcctgcagg atatccagga ggtgcagggc      180

tacgtgctca tcgctcacaa ccaagtgagg caggtcccac tgcagaggct gcggattgtg      240

cgaggcaccc agctctttga ggacaactat gccctggccg tgctagacaa tggagacccg      300

ctgaacaata ccacccctgt cacaggggcc tccccaggag gcctgcggga gctgcagctt      360

cgaagcctca cagagatctt gaaaggaggg gtcttgatcc agcggaaccc ccagctctgc      420

taccaggaca cgattttgtg gaaggacatc ttccacaaga acaaccagct ggctctcaca      480

ctgatagaca ccaaccgctc tcgggcctgc cacccctgtt ctccgatgtg taagggctcc      540

cgctgctggg gagagagttc tgaggattgt cagagcctga cgcgcactgt ctgtgccggt      600

ggctgtgccc gctgcaaggg gccactgccc actgactgct gccatgagca gtgtgctgcc      660

ggctgcacgg gccccaagca ctctgactgc ctggcctgcc tccacttcaa ccacagtggc      720

atctgtgagc tgcactgccc agccctggtc acctacaaca cagacacgtt tgagtccatg      780

cccaatcccg agggccggta tacattcggc gccagctgtg tgactgcctg tccctacaac      840

tacctttcta cggacgtggg atcctgcacc ctcgtctgcc ccctgcacaa ccaagaggtg      900

acagcagagg atggaacaca gcggtgtgag aagtgcagca agccctgtgc ccgagtgtgc      960

tatggtctgg gcatggagca cttgcgagag gtgagggcag ttaccagtgc caatatccag     1020

gagtttgctg gctgcaagaa gatctttggg agcctggcat ttctgccgga gagctttgat     1080

ggggacccag cctccaacac tgccccgctc cagccagagc agctccaagt gtttgagact     1140

ctggaagaga tcacaggtta cctatacatc tcagcatggc cggacagcct gcctgacctc     1200

agcgtcttcc agaacctgca agtaatccgg ggacgaattc tgcacaatgg cgcctactcg     1260

ctgaccctgc aagggctggg catcagctgg ctggggctgc gctcactgag ggaactgggc     1320

agtggactgg ccctcatcca ccataacacc cacctctgct tcgtgcacac ggtgccctgg     1380

gaccagctct ttcggaaccc gcaccaagct ctgctccaca ctgccaaccg gccagaggac     1440

gagtgtgtgg gcgagggcct ggcctgccac cagctgtgcg cccgagggca ctgctggggt     1500

ccagggccca cccagtgtgt caactgcagc cagttccttc ggggccagga gtgcgtggag     1560

gaatgccgag tactgcaggg gctccccagg gagtatgtga atgccaggca ctgtttgccg     1620

tgccaccctg agtgtcagcc ccagaatggc tcagtgacct gttttggacc ggaggctgac     1680

cagtgtgtgg cctgtgccca ctataaggac cctcccttct gcgtggcccg ctgccccagc     1740

ggtgtgaaac ctgacctctc ctacatgccc atctggaagt ttccagatga ggagggcgca     1800

tgccagcctt gccccatcaa ctgcacccac tcctgtgtgg acctggatga caagggctgc     1860

cccgccgagc agagagccag ccctctgacg                                      1890


<210>  3506
<211>  1872
<212>  DNA
<213>  Homo Sapiens

<400>  3506
tccgaggtgg gcaactctca ggcagtgtgt cctgggactc tgaatggcct gagtgtgacc       60

ggcgatgctg agaaccaata ccagacactg tacaagctct acgagaggtg tgaggtggtg      120

atggggaacc ttgagattgt gctcacggga cacaatgccg acctctcctt cctgcagtgg      180

attcgagaag tgacaggcta tgtcctcgtg gccatgaatg aattctctac tctaccattg      240

cccaacctcc gcgtggtgcg agggacccag gtctacgatg ggaagtttgc catcttcgtc      300

atgttgaact ataacaccaa ctccagccac gctctgcgcc agctccgctt gactcagctc      360

accgagattc tgtcaggggg tgtttatatt gagaagaacg ataagctttg tcacatggac      420

acaattgact ggagggacat cgtgagggac cgagatgctg agatagtggt gaaggacaat      480

ggcagaagct gtcccccctg tcatgaggtt tgcaaggggc gatgctgggg tcctggatca      540

gaagactgcc agacattgac caagaccatc tgtgctcctc agtgtaatgg tcactgcttt      600

gggcccaacc ccaaccagtg ctgccatgat gagtgtgccg ggggctgctc aggccctcag      660

gacacagact gctttgcctg ccggcacttc aatgacagtg gagcctgtgt acctcgctgt      720

ccacagcctc ttgtctacaa caagctaact ttccagctgg aacccaatcc ccacaccaag      780

tatcagtatg gaggagtttg tgtagccagc tgtccccata actttgtggt ggatcaaaca      840

tcctgtgtca gggcctgtcc tcctgacaag atggaagtag ataaaaatgg gctcaagatg      900

tgtgagcctt gtgggggact atgtcccaaa gcctgtgagg gaacaggctc tgggagccgc      960

ttccagactg tggactcgag caacattgat ggatttgtga actgcaccaa gatcctgggc     1020

aacctggact ttctgatcac cggcctcaat ggagacccct ggcacaagat ccctgccctg     1080

gacccagaga agctcaatgt cttccggaca gtacgggaga tcacaggtta cctgaacatc     1140

cagtcctggc cgccccacat gcacaacttc agtgtttttt ccaatttgac aaccattgga     1200

ggcagaagcc tctacaaccg gggcttctca ttgttgatca tgaagaactt gaatgtcaca     1260

tctctgggct tccgatccct gaaggaaatt agtgctgggc gtatctatat aagtgccaat     1320

aggcagctct gctaccacca ctctttgaac tggaccaagg tgcttcgggg gcctacggaa     1380

gagcgactag acatcaagca taatcggccg cgcagagact gcgtggcaga gggcaaagtg     1440

tgtgacccac tgtgctcctc tgggggatgc tggggcccag gccctggtca gtgcttgtcc     1500

tgtcgaaatt atagccgagg aggtgtctgt gtgacccact gcaactttct gaatggggag     1560

cctcgagaat ttgcccatga ggccgaatgc ttctcctgcc acccggaatg ccaacccatg     1620

gagggcactg ccacatgcaa tggctcgggc tctgatactt gtgctcaatg tgcccatttt     1680

cgagatgggc cccactgtgt gagcagctgc ccccatggag tcctaggtgc caagggccca     1740

atctacaagt acccagatgt tcagaatgaa tgtcggccct gccatgagaa ctgcacccag     1800

gggtgtaaag gaccagagct tcaagactgt ttaggacaaa cactggtgct gatcggcaaa     1860

acccatctga ca                                                         1872


<210>  3507
<211>  1878
<212>  DNA
<213>  Homo Sapiens

<400>  3507
cagtcagtgt gtgcaggaac ggagaataaa ctgagctctc tctctgacct ggaacagcag       60

taccgagcct tgcgcaagta ctatgaaaac tgtgaggttg tcatgggcaa cctggagata      120

accagcattg agcacaaccg ggacctctcc ttcctgcggt ctgttcgaga agtcacaggc      180

tacgtgttag tggctcttaa tcagtttcgt tacctgcctc tggagaattt acgcattatt      240

cgtgggacaa aactttatga ggatcgatat gccttggcaa tatttttaaa ctacagaaaa      300

gatggaaact ttggacttca agaacttgga ttaaagaact tgacagaaat cctaaatggt      360

ggagtctatg tagaccagaa caaattcctt tgttatgcag acaccattca ttggcaagat      420

attgttcgga acccatggcc ttccaacttg actcttgtgt caacaaatgg tagttcagga      480

tgtggacgtt gccataagtc ctgtactggc cgttgctggg gacccacaga aaatcattgc      540

cagactttga caaggacggt gtgtgcagaa caatgtgacg gcagatgcta cggaccttac      600

gtcagtgact gctgccatcg agaatgtgct ggaggctgct caggacctaa ggacacagac      660

tgctttgcct gcatgaattt caatgacagt ggagcatgtg ttactcagtg tccccaaacc      720

tttgtctaca atccaaccac ctttcaactg gagcacaatt tcaatgcaaa gtacacatat      780

ggagcattct gtgtcaagaa atgtccacat aactttgtgg tagattccag ttcttgtgtg      840

cgtgcctgcc ctagttccaa gatggaagta gaagaaaatg ggattaaaat gtgtaaacct      900

tgcactgaca tttgcccaaa agcttgtgat ggcattggca caggatcatt gatgtcagct      960

cagactgtgg attccagtaa cattgacaaa ttcataaact gtaccaagat caatgggaat     1020

ttgatctttc tagtcactgg tattcatggg gacccttaca atgcaattga agccatagac     1080

ccagagaaac tgaacgtctt tcggacagtc agagagataa caggtttcct gaacatacag     1140

tcatggccac caaacatgac tgacttcagt gttttttcta acctggtgac cattggtgga     1200

agagtactct atagtggcct gtccttgctt atcctcaagc aacagggcat cacctctcta     1260

cagttccagt ccctgaagga aatcagcgca ggaaacatct atattactga caacagcaac     1320

ctgtgttatt atcataccat taactggaca acactcttca gcacaatcaa ccagagaata     1380

gtaatccggg acaacagaaa agctgaaaat tgtactgctg aaggaatggt gtgcaaccat     1440

ctgtgttcca gtgatggctg ttggggacct gggccagacc aatgtctgtc gtgtcgccgc     1500

ttcagtagag gaaggatctg catagagtct tgtaacctct atgatggtga atttcgggag     1560

tttgagaatg gctccatctg tgtggagtgt gacccccagt gtgagaagat ggaagatggc     1620

ctcctcacat gccatggacc gggtcctgac aactgtacaa agtgctctca ttttaaagat     1680

ggcccaaact gtgtggaaaa atgtccagat ggcttacagg gggcaaacag tttcattttc     1740

aagtatgctg atccagatcg ggagtgccac ccatgccatc caaactgcac ccaagggtgt     1800

aacggtccca ctagtcatga ctgcatttac tacccatgga cgggccattc cactttacca     1860

caacatgcta gaactccc                                                   1878


<210>  3508
<211>  138
<212>  DNA
<213>  Homo Sapiens

<400>  3508
gtgtcaataa caaagtgtag ctctgacatg aatggctatt gtttgcatgg acagtgcatc       60

tatctggtgg acatgagtca aaactactgc aggtgtgaag tgggttatac tggtgtccga      120

tgtgaacact tcttttta                                                    138


<210>  3509
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  3509
cacgcagggg atgccggcaa gttccacgtg gccctactag ggggcacagc cgagctgctc       60

tgccctctct ccctctggcc cgggacggta cccaaggagg tgaggtggct gcggtcccca      120

ttcccgcagc gctcccaggc tgttcacata ttccgggatg ggaaggacca ggatgaagat      180

ctgatgccgg aatataaggg gaggacggtg ctagtgagag atgcccaaga gggaagtgtc      240

actctgcaga tccttgacgt gcgccttgag gaccaagggt cttaccgatg tctgatccaa      300

gttggaaatc tgagtaaaga ggacaccgtg atcctgcagg ttgcagcccc atctgtgggg      360

agtctctccc cctcagca                                                    378


<210>  3510
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3510
cagctgcaac tgcacttgcc cgccaaccgg ttgcaggcgg tggagggagg ggaagtggtg       60

cttccagcgt ggtacacctt gcacggggag gtgtcttcat cccagccatg ggaggtgccc      120

tttgtgatgt ggttcttcaa acagaaagaa aaggaggatc aggtgttgtc ctacatcaat      180

ggggtcacaa caagcaaacc tggagtatcc ttggtctact ccatgccctc ccggaacctg      240

tccctgcggc tggagggtct ccaggagaaa gactctggcc cctacagctg ctccgtgaat      300

gtgcaagaca aacaaggcaa atctaggggc cacagcatca aaaccttaga actcaatgta      360

ctggttcctc cagctcctcc atcctgccgt ctccagggtg tgccccatgt gggggcaaac      420

gtgaccctga gctgccagtc tccaaggagt aagcccgctg tccaatacca gtgggatcgg      480

cagcttccat ccttccagac tttctttgca ccagcattag atgtcatccg tgggtcttta      540

agcctcacca acctttcgtc ttccatggct ggagtctatg tctgcaaggc ccacaatgag      600

gtgggcactg cccaatgtaa tgtgacgctg gaagtgagca cagggcctgg agctgca         657


<210>  3511
<211>  1719
<212>  DNA
<213>  Homo Sapiens

<400>  3511
aaaacatgta gacggcaatt ggtggaagaa tggcatccac aaccctcatc atatgtggta       60

aattggacac taacagaaaa catctgcttg gacttctaca gagattgctg gtttttgggt      120

gtaaacacta aaatagatac ttcaggcaat caagctgttc cccagatttg ccctttgcaa      180

attcaattag gagatatcct tgtaatttct tctgaaccat ctcttcaatt tccagaaata      240

aatttgatga atgtttctga aacatctttc gttggctgtg tgcaaaatac cacaatggaa      300

gatcagttac tttttggctg cagactaaaa ggaatgcaca ctgttaattc taagtggctg      360

agtgttggga cacattattt tatcacagtt atggcaagtg gtccatcacc ttgtccactg      420

ggacttcgac taaatgtgac agtgaaacag cagttctgcc aggaatctct gagttcagaa      480

ttttgctctg gtcatggtaa atgtcttagt gaagcttgga gcaagacata tagctgccat      540

tgccagcctc cattttctgg aaaatactgc caggaacttg atgcatgttc ttttaaacca      600

tgtaaaaata atggcagttg cattaataaa agagaaaatt gggatgagca agcatatgaa      660

tgtgtctgtc acccaccatt tacaggaaag aattgctcag aaataattgg ccagtgtcaa      720

ccacatgtct gtttccatgg aaactgcagc aatattactt caaatagttt catttgtgaa      780

tgtgatgagc aattttcagg tccattctgt gaggtgtcag caaaaccttg tgtttctctg      840

cttttttgga aaagaggaat ttgcccaaat agcagttctg cttatactta tgaatgccca      900

aaaggatctt ccagccaaaa tggtgaaact gatgtcagtg agttttcatt agtaccatgt      960

cagaatggta ctgactgcat caaaatatca aatgatgtta tgtgcatctg ttcaccaata     1020

tttacagatt tgctttgtaa gagcattcaa acatcatgtg agtcatttcc tttgaggaat     1080

aacgctacat gtaagaaatg tgagaaagat tatccttgca gctgtatatc aggatttact     1140

gaaaaaaact gtgagaaagc aattgaccac tgtaaactgc tcagcatcaa ctgtctgaat     1200

gaagaatggt gtttcaatat aattggaaga ttcaaatatg tatgcattcc agggtgcaca     1260

aaaaatccat gttggttttt gaagaatgtt tacctaattc atcaacacct ctgctactgt     1320

ggagtcacct tccatggtat ttgccaagat aaaggtcctg ctcaatttga atatgtgtgg     1380

caattgggat ttgcaggatc tgaaggcgaa aagtgccaag gggttattga tgcctatttc     1440

tttctggctg caaactgcac tgaagatgca acctatgtga acgatcctga agataataat     1500

tcttcatgtt ggttcccaca tgaaggcaca aaagagattt gtgcaaatgg atgcagttgt     1560

ttgagtgaag aagacagtca ggaatatcgg tatctatgtt ttctcagatg ggctggcaac     1620

atgtatctgg aaaatacaac tgatgatcaa gaaaatgagt gtcaacatga agctgtttgt     1680

aaagatgaaa ttaatagacc caggtattta tgtatcatt                            1719


<210>  3512
<211>  1464
<212>  DNA
<213>  Homo Sapiens

<400>  3512
atggggcgcc cactgcacct cgtcctgctc agtgcctccc tggctggcct cctgctgctc       60

ggggaaagtc tgttcatccg cagggagcag gccaacaaca tcctggcgag ggtcacgagg      120

gccaattcct ttcttgaaga gatgaagaaa ggacacctcg aaagagagtg catggaagag      180

acctgctcat acgaagaggc ccgcgaggtc tttgaggaca gcgacaagac gaatgaattc      240

tggaataaat acaaagatgg cgaccagtgt gagaccagtc cttgccagaa ccagggcaaa      300

tgtaaagacg gcctcgggga atacacctgc acctgtttag aaggattcga aggcaaaaac      360

tgtgaattat tcacacggaa gctctgcagc ctggacaacg gggactgtga ccagttctgc      420

cacgaggaac agaactctgt ggtgtgctcc tgcgcccgcg ggtacaccct ggctgacaac      480

ggcaaggcct gcattcccac agggccctac ccctgtggga aacagaccct ggaacgcagg      540

aagaggtcag tggcccaggc caccagcagc agcggggagg cccctgacag catcacatgg      600

aagccatatg atgcagccga cctggacccc accgagaacc ccttcgacct gcttgacttc      660

aaccagacgc agcctgagag gggcgacaac aacctcacca ggatcgtggg aggccaggaa      720

tgcaaggacg gggagtgtcc ctggcaggcc ctgctcatca atgaggaaaa cgagggtttc      780

tgtggtggaa ctattctgag cgagttctac atcctaacgg cagcccactg tctctaccaa      840

gccaagagat tcaaggtgag ggtaggggac cggaacacgg agcaggagga gggcggtgag      900

gcggtgcacg aggtggaggt ggtcatcaag cacaaccggt tcacaaagga gacctatgac      960

ttcgacatcg ccgtgctccg gctcaagacc cccatcacct tccgcatgaa cgtggcgcct     1020

gcctgcctcc ccgagcgtga ctgggccgag tccacgctga tgacgcagaa gacggggatt     1080

gtgagcggct tcgggcgcac ccacgagaag ggccggcagt ccaccaggct caagatgctg     1140

gaggtgccct acgtggaccg caacagctgc aagctgtcca gcagcttcat catcacccag     1200

aacatgttct gtgccggcta cgacaccaag caggaggatg cctgccaggg ggacagcggg     1260

ggcccgcacg tcacccgctt caaggacacc tacttcgtga caggcatcgt cagctgggga     1320

gagggctgtg cccgtaaggg gaagtacggg atctacacca aggtcaccgc cttcctcaag     1380

tggatcgaca ggtccatgaa aaccaggggc ttgcccaagg ccaagagcca tgccccggag     1440

gtcataacgt cctctccatt aaag                                            1464


<210>  3513
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  3513
agtgttacag tgcactcttc tgaacctgaa gtcagaattc ctgagaataa tcctgtgaag       60

ttgtcctgtg cctactcggg cttttcttct ccccgtgtgg agtggaagtt tgaccaagga      120

gacaccacca gactcgtttg ctataataac aagatcacag cttcctatga ggaccgggtg      180

accttcttgc caactggtat caccttcaag tccgtgacac gggaagacac tgggacatac      240

acttgtatgg tctctgagga aggcggcaac agctatgggg aggtcaaggt caagctcatc      300

gtgcttgtgc ctccatccaa gcctacagtt aacatcccct cctctgccac cattgggaac      360

cgggcagtgc tgacatgctc agaacaagat ggttccccac cttctgaata cacctggttc      420

aaagatggga tagtgatgcc tacgaatccc aaaagcaccc gtgccttcag caactcttcc      480

tatgtcctga atcccacaac aggagagctg gtctttgatc ccctgtcagc ctctgatact      540

ggagaataca gctgtgaggc acggaatggg tatgggacac ccatgacttc aaatgctgtg      600

cgcatggaag ctgtggagcg gaatgtgggg gtc                                   633


<210>  3514
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  3514
gtcgttggcg ggctggtggc gctacgcggg gcgcacccct acatcgccgc gctgtactgg       60

ggccacagtt tctgcgccgg cagcctcatc gccccctgct gggtgctgac ggccgctcac      120

tgcctgcagg accggcccgc acccgaggat ctgacggtgg tgctcggcca ggaacgccgt      180

aaccacagct gtgagccgtg ccagacgttg gccgtgcgct cctaccgctt gcacgaggcc      240

ttctcgcccg tcagctacca gcacgacctg gctctgttgc gccttcagga ggatgcggac      300

ggcagctgcg cgctcctgtc gccttacgtt cagccggtgt gcctgccaag cggcgccgcg      360

cgaccctccg agaccacgct ctgccaggtg gccggctggg gccaccagtt cgagggggcg      420

gaggaatatg ccagcttcct gcaggaggcg caggtaccgt tcctctccct ggagcgctgc      480

tcagccccgg acgtgcacgg atcctccatc ctccccggca tgctctgcgc agggttcctc      540

gagggcggca ccgatgcgtg ccagggtgat tccggaggcc cgctggtgtg tgaggaccaa      600

gctgcagagc gccggctcac cctgcaaggc atcatcagct ggggatcggg ctgtggtgac      660

cgcaacaagc caggcgtcta caccgatgtg gcctactacc tggcctggat ccgggagcac      720

accgtttcc                                                              729


<210>  3515
<211>  2082
<212>  DNA
<213>  Homo Sapiens

<400>  3515
ggcgtcaacc tgcaagagtt tcttaatgtc acgagcgttc acctgttcaa ggagagatgg       60

gacactaaca aggtggacca ccacactgac aagtatgaaa acaacaagct gattgtccgc      120

agagggcagt ctttctatgt gcagattgac ttcagtcgtc catatgaccc cagaagggat      180

ctcttcaggg tggaatacgt cattggtcgc tacccacagg agaacaaggg aacctacatc      240

ccagtgccta tagtctcaga gttacaaagt ggaaagtggg gggccaagat tgtcatgaga      300

gaggacaggt ctgtgcggct gtccatccag tcttccccca aatgtattgt ggggaaattc      360

cgcatgtatg ttgctgtctg gactccctat ggcgtacttc gaaccagtcg aaacccagaa      420

acagacacgt acattctctt caatccttgg tgtgaagatg atgctgtgta tctggacaat      480

gagaaagaaa gagaagagta tgtcctgaat gacatcgggg taatttttta tggagaggtc      540

aatgacatca agaccagaag ctggagctat ggtcagtttg aagatggcat cctggacact      600

tgcctgtatg tgatggacag agcacaaatg gacctctctg gaagagggaa tcccatcaaa      660

gtcagccgtg tggggtctgc aatggtgaat gccaaagatg acgaaggtgt cctcgttgga      720

tcctgggaca atatctatgc ctatggcgtc cccccatcgg cctggactgg aagcgttgac      780

attctattgg aataccggag ctctgagaat ccagtccggt atggccaatg ctgggttttt      840

gctggtgtct ttaacacatt tttacgatgc cttggaatac cagcaagaat tgttaccaat      900

tatttctctg cccatgataa tgatgccaat ttgcaaatgg acatcttcct ggaagaagat      960

gggaacgtga attccaaact caccaaggat tcagtgtgga actaccactg ctggaatgaa     1020

gcatggatga caaggcctga ccttcctgtt ggatttggag gctggcaagc tgtggacagc     1080

accccccagg aaaatagcga tggcatgtat cggtgtggcc ccgcctcggt tcaagccatc     1140

aagcacggcc atgtctgctt ccaatttgat gcaccttttg tttttgcaga ggtcaacagc     1200

gacctcattt acattacagc taagaaagat ggcactcatg tggtggaaaa tgtggatgcc     1260

acccacattg ggaaattaat tgtgaccaaa caaattggag gagatggcat gatggatatt     1320

actgatactt acaaattcca agaaggtcaa gaagaagaga gattggccct agaaactgcc     1380

ctgatgtacg gagctaaaaa gcccctcaac acagaaggtg tcatgaaatc aaggtccaac     1440

gttgacatgg actttgaagt ggaaaatgct gtgctgggaa aagacttcaa gctctccatc     1500

accttccgga acaacagcca caaccgttac accatcacag cttatctctc agccaacatc     1560

accttctaca ccggggtccc gaaggcagaa ttcaagaagg agacgttcga cgtgacgctg     1620

gagcccttgt ccttcaagaa agaggcggtg ctgatccaag ccggcgagta catgggtcag     1680

ctgctggaac aagcgtccct gcacttcttt gtcacagctc gcatcaatga gaccagggat     1740

gttctggcca agcaaaagtc caccgtgcta accatccctg agatcatcat caaggtccgt     1800

ggcactcagg tagttggttc tgacatgact gtgatagttg agtttaccaa tcctttaaaa     1860

gaaaccctgc gaaatgtctg ggtacacctg gatggtcctg gagtaacaag accaatgaag     1920

aagatgttcc gtgaaatccg gcccaactcc accgtgcagt gggaagaagt gtgccggccc     1980

tgggtctctg ggcatcggaa gctgatagcc agcatgagca gtgactccct gagacatgtg     2040

tatggcgagc tggacgtgca gattcaaaga cgaccttcca tg                        2082


<210>  3516
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3516
tcaggcacta caaatactgt ggcagcatat aatttaactt ggaaatcaac taatttcaag       60

acaattttgg agtgggaacc caaacccgtc aatcaagtct acactgttca aataagcact      120

aagtcaggag attggaaaag caaatgcttt tacacaacag acacagagtg tgacctcacc      180

gacgagattg tgaaggatgt gaagcagacg tacttggcac gggtcttctc ctacccggca      240

gggaatgtgg agagcaccgg ttctgctggg gagcctctgt atgagaactc cccagagttc      300

acaccttacc tggagacaaa cctcggacag ccaacaattc agagttttga acaggtggga      360

acaaaagtga atgtgaccgt agaagatgaa cggactttag tcagaaggaa caacactttc      420

ctaagcctcc gggatgtttt tggcaaggac ttaatttata cactttatta ttggaaatct      480

tcaagttcag gaaagaaaac agccaaaaca aacactaatg agtttttgat tgatgtggat      540

aaaggagaaa actactgttt cagtgttcaa gcagtgattc cctcccgaac agttaaccgg      600

aagagtacag acagcccggt agagtgtatg ggccaggaga aaggggaatt cagagaa         657


<210>  3517
<211>  1218
<212>  DNA
<213>  Homo Sapiens

<400>  3517
gccaacgcgt tcctggagga gctgcggccg ggctccctgg agagggagtg caaggaggag       60

cagtgctcct tcgaggaggc ccgggagatc ttcaaggacg cggagaggac gaagctgttc      120

tggatttctt acagtgatgg ggaccagtgt gcctcaagtc catgccagaa tgggggctcc      180

tgcaaggacc agctccagtc ctatatctgc ttctgcctcc ctgccttcga gggccggaac      240

tgtgagacgc acaaggatga ccagctgatc tgtgtgaacg agaacggcgg ctgtgagcag      300

tactgcagtg accacacggg caccaagcgc tcctgtcggt gccacgaggg gtactctctg      360

ctggcagacg gggtgtcctg cacacccaca gttgaatatc catgtggaaa aatacctatt      420

ctagaaaaaa gaaatgccag caaaccccaa ggccgaattg tggggggcaa ggtgtgcccc      480

aaaggggagt gtccatggca ggtcctgttg ttggtgaatg gagctcagtt gtgtgggggg      540

accctgatca acaccatctg ggtggtctcc gcggcccact gtttcgacaa aatcaagaac      600

tggaggaacc tgatcgcggt gctgggcgag cacgacctca gcgagcacga cggggatgag      660

cagagccggc gggtggcgca ggtcatcatc cccagcacgt acgtcccggg caccaccaac      720

cacgacatcg cgctgctccg cctgcaccag cccgtggtcc tcactgacca tgtggtgccc      780

ctctgcctgc ccgaacggac gttctctgag aggacgctgg ccttcgtgcg cttctcattg      840

gtcagcggct ggggccagct gctggaccgt ggcgccacgg ccctggagct catggtcctc      900

aacgtgcccc ggctgatgac ccaggactgc ctgcagcagt cacggaaggt gggagactcc      960

ccaaatatca cggagtacat gttctgtgcc ggctactcgg atggcagcaa ggactcctgc     1020

aagggggaca gtggaggccc acatgccacc cactaccggg gcacgtggta cctgacgggc     1080

atcgtcagct ggggccaggg ctgcgcaacc gtgggccact ttggggtgta caccagggtc     1140

tcccagtaca tcgagtggct gcaaaagctc atgcgctcag agccacgccc aggagtcctc     1200

ctgcgagccc catttccc                                                   1218


<210>  3518
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  3518
tataattcag gtaaattgga agagtttgtt caagggaacc ttgagagaga atgtatggaa       60

gaaaagtgta gttttgaaga agcacgagaa gtttttgaaa acactgaaag aacaactgaa      120

ttttggaagc agtatgttga tggagatcag tgtgagtcca atccatgttt aaatggcggc      180

agttgcaagg atgacattaa ttcctatgaa tgttggtgtc cctttggatt tgaaggaaag      240

aactgtgaat tagatgtaac atgtaacatt aagaatggca gatgcgagca gttttgtaaa      300

aatagtgctg ataacaaggt ggtttgctcc tgtactgagg gatatcgact tgcagaaaac      360

cagaagtcct gtgaaccagc agtgccattt ccatgtggaa gagtttctgt ttcacaaact      420

tctaagctca cccgtgctga gactgttttt cctgatgtgg actatgtaaa ttctactgaa      480

gctgaaacca ttttggataa catcactcaa agcacccaat catttaatga cttcactcgg      540

gttgttggtg gagaagatgc caaaccaggt caattccctt ggcaggttgt tttgaatggt      600

aaagttgatg cattctgtgg aggctctatc gttaatgaaa aatggattgt aactgctgcc      660

cactgtgttg aaactggtgt taaaattaca gttgtcgcag gtgaacataa tattgaggag      720

acagaacata cagagcaaaa gcgaaatgtg attcgaatta ttcctcacca caactacaat      780

gcagctatta ataagtacaa ccatgacatt gcccttctgg aactggacga acccttagtg      840

ctaaacagct acgttacacc tatttgcatt gctgacaagg aatacacgaa catcttcctc      900

aaatttggat ctggctatgt aagtggctgg ggaagagtct tccacaaagg gagatcagct      960

ttagttcttc agtaccttag agttccactt gttgaccgag ccacatgtct tcgatctaca     1020

aagttcacca tctataacaa catgttctgt gctggcttcc atgaaggagg tagagattca     1080

tgtcaaggag atagtggggg accccatgtt actgaagtgg aagggaccag tttcttaact     1140

ggaattatta gctggggtga agagtgtgca atgaaaggca aatatggaat atataccaag     1200

gtatcccggt atgtcaactg gattaaggaa aaaacaaagc tcact                     1245


<210>  3519
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  3519
agtcctgaac cgggggcacc gtctcgtagt agggcaagga gagagccgcc acctggaaat       60

gaattaccta gaggtccagg tgagagtagg gcaggccctg cggcaagacc ccctgagccg      120

accgcagaga gagctcactc agtcgatcct agagacgcct ggatgctatt cgttaggcag      180

tctgataaag gtgtcaatgg taagaagcgt tctcgtggaa aggcgaagaa gttaaaattt      240

gggctgcccg gacctcctgg gccgcctggt cctcagggcc ctcccggacc aataatccca      300

cccgaggcct tattaaaaga gtttcagctg cttctaaaag gtgccgtcag gcaacgtgaa      360

agagctgaac ccgaaccttg tacttgcggc cccgcaggcc cggtggcagc ttcattggcg      420

ccggtatcag ccacagcggg cgaagacgat gacgatgtag taggggatgt attggcgctg      480

ttagccgctc cattagcacc gggtcctagg gctcctcgtg ttgaagcagc gtttttgtgc      540

cgtctgagga gggacgccct tgtggaaaga cgtgcgttac atgagttagg cgtttattat      600

cttcccgacg ctgaaggagc tttcaggagg ggcccaggtt taaatttaac ttccggtcag      660

tacagagcgc cagtagcagg gttctatgct ctggccgcta ctcttcatgt ggcactagga      720

gagccacctc gtaggggccc gccgagacca agagatcatc ttagacttct tatctgcatc      780

caatctagat gtcagagaaa cgcgtccctg gaagcgatca tgggtcttga gtcttccagc      840

gaattgttca ctatcagtgt aaatggggtt ctttatcttc agatgggaca gtggacaagt      900

gtgttcttag ataacgcttc aggatgtagt ttaaccgttc gttcaggatc acacttcagc      960

gcagtattgc taggagtt                                                    978


<210>  3520
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  3520
aagacgctgc gggagcccgg cgccggagcc caagaggtga cgttaaaggt gcacatcagc       60

gacgccagca cccaccagcc cgtagcagat gcgctcatcg agatcttcac caaccaggcc      120

tccatagcct ctggcacctc ggggactgat ggcgtcgcct ttatcaagtt ccagtataag      180

ctgggcagtc agttgattgt caccgcctcg aagcatgcct acgtgccaaa ctctgcccca      240

tggaagccaa tccggttacc tgtattttcc tctctgagcc ttggcctgct tccagaacgc      300

tctgccactc taatggtata tgaagatgtc gtccaaatag tatcaggatt ccaaggtgcc      360

cggccacagc ctcgcgttca tttccagaga agggctctga ggttgcctga gaacaccagc      420

tacagtgacc tgaccgcgtt tctcacggcc gccagctccc cttcggaggt ggacagtttt      480

ccttatttgc gaggattaga cggaaatgga acaggaaaca gcaccaggca tgacctgacc      540

ccagtcacag ccgtcagcgt ccacttgctg agcagtaatg gaacgccggt gctggtggat      600

ggtcccatct atgtcactgt gcccctggcc acgcagagca gcctgaggca caatgcctat      660

gtcgcggcgt ggcggtttga ccagaagctg ggaacgtggc tgaagagcgg tctgggtctt      720

gtgcaccagg aaggcagcca gctgacgtgg acatacattg ccccccagtt ggggtactgg      780

gtggccgcca tgtcccctcc catcccaggt cccgttgtaa cacaggacat taccacgtat      840

cacacg                                                                 846


<210>  3521
<211>  1077
<212>  DNA
<213>  Homo Sapiens

<400>  3521
tttgaaattg tagagaagga aaatatattt caaaggacgc cctgccctgc gtttcttatg       60

tttgagaacg ccgcctatct ggccgacatg agctttgaat taccatgtca ctgtaagcca      120

gaagaagttc ccgctgtcgt gtggttctac cagaaacatc taggcagttc ccacactaag      180

gtgctaaccg acttcgacgg tagggtacta accgaggccg cccaagtgag ggtgggatca      240

gatatgttga cgagattcag catccgtatg ttcagcttgt tagttttcag ggctcaatca      300

gaagattccg gtctttactt ctgcggaacg agaaagggag actattttta tgcctacgac      360

gtggatatcc aaaacagcga aggaatggtc gctacattcc aggataaggg acaagaacct      420

ttcgcggacg agtattatgg acatttgcat gtattcacca ctttttggga gtggaccccg      480

tgtgataggt gtggcgtgcg tggagagcaa tggagaatag gtctgtgcta cctgcaatct      540

cctgatttat caccgagata ccttaaggct gttccagacg tcgtgtcctg tggatcaaga      600

gccgttccgc gtaaattaag gaccaaagca agggaccaca cacctgaagt tttagtcaga      660

tcttgtctgg taccatgcga gaaaactaaa accattaggg aaggcgtctt ggcaattata      720

aactatgtct ctaaggttgg ctcacgtccc tgggttccac aggtgcccat tcaattccat      780

cagcaaagat tggggcatgg attaatcatc tcatgcccag gggccagacc cgagcacgcg      840

gtggcatggg acaaggatcg tcagcatctg tatcgtaccc agtacttaaa gggagttaat      900

cgttccatga gagtcttcat tgatcatggg aaccaactac acataagatt tacccaatta      960

gatgaccgtg ggatctatta ttgttggagg caaggagtac tagttgccgg gtttagatta     1020

ggagtaactt cccacgggca ttacccagcg agcttttcag acccagagac caggtca        1077


<210>  3522
<211>  954
<212>  DNA
<213>  Homo Sapiens

<400>  3522
ttctactttt ccatcagctg ccccagtggt aagcagtgcc aacaggccct actctcaggc       60

aatgatattc tcctgtattg caactcctcg ggggcgcact ggtactattt attcacacaa      120

ggcaagaagg gcaggctcac cagcctcacc aatatttcca atatggaaat aatgcccgag      180

ggcagccttc tcattaaaga tccattgccc tcccagacgg gcctctacca ctgctggaac      240

aagaatggcc gccaagtggt gcagtatgaa attgattttc aggatgtcac caccctgcat      300

ataacacaca aggacctggg tcagaggccc ctgcagaacg agaccctgca tttgggcagc      360

aaacagctca tttttacctg gtgggagccc tggcaggact gcaaccgctg tgaggagccg      420

ggcgagcgta aacgcctggg gtaccgctac attgaggagc ctctggagga agccatgccc      480

tgctggctct atctgggaga ggtgctggtg tggtctagcc gcttgcggcc tgagctgcag      540

gtggaagcct gccacgtcca gtgcaccaat aacacacagt taagggtgga ttacgtcatt      600

tttgacaact tcaggctcga tgagaagaca gaatttgtgt ggctcgactg tcccttagga      660

tccatgtaca ggcccgtcaa ctggcgtgcc aacgacaccc ccctgacgtg ggagagccag      720

ctctccggcc aggacttcac cacctttctg gacccctcca ccggcggcag gcagctgcag      780

gttttccagc cggccgtcta caagtgcttc gtgcagcagg agctcgtggc ccagttcaaa      840

cccgccgcca gtctggagac gctggaggct cagtggagag agaacgatgc ccagtggcgg      900

gaggcaagga aggccctgcg gggcagggcg gactccgtgc tcaaggggct gaag            954


<210>  3523
<211>  1476
<212>  DNA
<213>  Homo Sapiens

<400>  3523
gacttcagct ccgacccctc ctccaacctc tcgtcccact cgctggagaa actgccgccc       60

gcggccgagc cggccgagcg cgccttgcgg gggcgggatc ccggcgccct aagaccccac      120

gaccccgcgc accggccgct gctgcgagac cccggcccgc gtcggtccga gtcgcccccc      180

ggccccggcg gagacgcctc cctcctggcc aggctgttcg agcacccgct ttaccgggtg      240

gcggttccgc cgctcacgga ggaggacgtc ctgttcaatg tgaacagcga caccaggctc      300

agccccaaag cggcggagaa cccggactgg ccgcatgcgg gtgctgaagg tgcagaattc      360

ctctcccccg gggaggcggc cgtggactcc tatcccaact ggctcaagtt ccacattggt      420

atcaaccggt acgagctgta ctccagacac aacccggcca tcgaggccct gctgcacgac      480

ctcagctccc agaggatcac cagcgtggcc atgaagtcgg ggggcacgca gctgaagctc      540

atcatgacct tccagaatta cgggcaagcg ctgttcaaac ccatgaaaca aacgagggag      600

caggagacac cccctgactt tttttatttc tctgactacg agaggcacaa tgcggagatt      660

gctgccttcc acctggacag gatcctggac ttccgccggg tccctcccgt ggccggcagg      720

atggtcaaca tgaccaagga gatccgggac gtcacacggg acaagaagct ctggaggacc      780

ttcttcatct ctccagccaa caacatctgc ttctacggcg agtgttccta ctactgctcc      840

acggagcacg ccctgtgcgg gaagccagac cagatcgagg gctcgctggc ggccttcctg      900

cccgacctgt ccctggccaa gaggaagacc tggcggaacc cttggcggcg ttcctaccac      960

aagcgcaaga aggccgagtg ggaggtggac cctgactact gcgaggaggt gaagcagaca     1020

ccgccctacg acagcagcca ccgcatcctg gacgtcatgg acatgacgat cttcgacttc     1080

ctcatgggaa acatggaccg tcaccactac gagacttttg agaagtttgg gaatgaaacg     1140

ttcatcatcc acttagacaa tggaagaggg tttgggaagt attcgcacga cgagctctcc     1200

atcctggtgc cgctacagca gtgctgcagg atccggaagt ccacctacct gcgtctgcag     1260

ctcctggcca aggaggagta caagctgagc ctgctgatgg ccgagtctct gcggggggac     1320

caggtggcac ccgtgctgta ccagccgcac ctggaggccc tggaccggcg gctccgcgtc     1380

gtgctaaagg ccgtccggga ctgcgtggag aggaacgggc tccacagcgt ggtggatgac     1440

gacctggaca ctgagcacag agccgcctcg gcgagg                               1476


<210>  3524
<211>  828
<212>  DNA
<213>  Homo Sapiens

<400>  3524
ggtactgcta caaggttcag tggtcagagc tatgtgcggt acagggcccc agcggctcgg       60

aactggcaca tccatttcta tctgaaaaca ctccagccac aggccattct tctattcacc      120

aatgaaacag cgtccgtctc cctgaagctg gccagtggag tgccccagct ggaataccac      180

tgtctgggtg gtttctatgg aaacctttcc tcccagcgcc atgtgaatga ccacgagtgg      240

cactccatcc tggtggagga gatggacgct tccattcgcc tgatggttga cagcatgggc      300

aacacctccc ttgtggtccc agagaactgc cgtggtctga ggcccgaaag gcacctcttg      360

ctgggcggcc tcattctgtt gcattcttcc tcgaatgtct cccagggctt tgaaggctgc      420

ctggatgctg tcgtggtcaa cgaagaggct ctagatctgc tggcccctgg caagacggtg      480

gcaggcttgc tggagacaca agccctcacc cagtgctgcc tccacagtga ctactgcagc      540

cagaacacat gcctcaatgg tgggaagtgc tcatggaccc acggggcagg ctatgtctgc      600

aaatgtcccc cacagttctc tgggaagcac tgtgaacaag gaagggagaa ctgtactttt      660

gcaccctgcc tggaaggtgg aacttgcatc ctctccccca aaggagcttc ctgtaactgc      720

cctcatcctt acacaggaga caggtgtgaa atggaggcga ggggttgttc agaaggacac      780

tgcctagtca ctcccgagat ccaaaggggg gactgggggc agcaggag                   828


<210>  3525
<211>  1962
<212>  DNA
<213>  Homo Sapiens

<400>  3525
gatgtcctcc tggaggcctg ctgtgcggac ggacaccgga tggccactca tcagaaggac       60

tgctcgctgc catatgctac ggaatccaaa gaatgcagga tggtgcagga gcagtgctgc      120

cacagccagc tggaggagct gcactgtgcc acgggcatca gcctggccaa cgagcaggac      180

cgctgtgcca cgccccacgg tgacaacgcc agcctggagg ccacatttgt gaagaggtgc      240

tgccattgct gtctgctggg gagggcggcc caggcccagg gccagagctg cgagtacagc      300

ctcatggttg gctaccagtg tggacaggtc ttccgggcat gctgtgtcaa gagccaggag      360

accggagatt tggatgtcgg gggcctccaa gaaacggata agatcattga ggttgaggag      420

gaacaagagg acccatatct gaatgaccgc tgccgaggag gcgggccctg caagcagcag      480

tgccgagaca cgggtgacga ggtggtctgc tcctgcttcg tgggctacca gctgctgtct      540

gatggtgtct cctgtgaaga tgtcaatgaa tgcatcacgg gcagccacag ctgccggctt      600

ggagaatcct gcatcaacac agtgggctct ttccgctgcc agcgggacag cagctgcggg      660

actggctatg agctcacaga ggacaatagc tgcaaagata ttgacgagtg tgagagtggt      720

attcataact gcctccccga ttttatctgt cagaatactc tgggatcctt ccgctgccga      780

cccaagctac agtgcaagag tggctttata caagatgctc taggcaactg tattgatatc      840

aatgagtgtt tgagtatcag tgccccgtgc cctatcgggc atacatgcat caacacagag      900

ggctcctaca cgtgccagaa gaacgtgccc aactgtggcc gtggctacca tctcaacgag      960

gagggaacgc gctgtgttga tgtggacgag tgcgcgccac ctgctgagcc ctgtgggaag     1020

ggacatcgct gcgtgaactc tcccggcagt ttccgctgcg aatgcaagac gggttactat     1080

tttgacggca tcagcaggat gtgtgtcgat gtcaacgagt gccagcgcta ccccgggcgc     1140

ctgtgtggcc acaagtgcga gaacacgctg ggctcctacc tctgcagctg ttccgtgggc     1200

ttccggctct ctgtggatgg caggtcatgt gaagacatca atgagtgcag cagcagcccc     1260

tgtagccagg agtgtgccaa cgtctacggc tcctaccagt gttactgccg gcgaggctac     1320

cagctcagcg atgtggatgg agtcacctgt gaagacatcg acgagtgcgc cctgcccacc     1380

gggggccaca tctgctccta ccgctgcatc aacatccctg gaagcttcca gtgcagctgc     1440

ccctcgtctg gctacaggct ggcccccaat ggcagcaact gccaagacat tgatgagtgt     1500

gtgactggca tccacaactg ctccatcaac gagacctgct tcaacatcca gggcggcttc     1560

cgctgcctgg ccttcgagtg ccctgagaac taccgccgct ccgcagccac ccgctgtgag     1620

cgcttgcctt gccatgagaa tcgggagtgc tccaagctgc ctctgagaat aacctactac     1680

cacctctctt tccccaccaa catccaagcg cccgcggtgg ttttccgcat gggcccctcc     1740

agtgctgtcc ccggggacag catgcagctg gccatcaccg gcggcaatga ggagggcttt     1800

ttcaccaccc ggaaggtgag cccccacagt ggggtggtgg ccctcaccaa gcctgtcccc     1860

gagcccaggg acttgctcct gaccgtcaag atggatctct ctcgccacgg caccgtcagc     1920

tcctttgtgg ccaagctttt catctttgtg tctgcagagc tc                        1962


<210>  3526
<211>  3471
<212>  DNA
<213>  Homo Sapiens

<400>  3526
gcccctcggc aggactgcac gggcgtggag tgcccgccgc tggagaactg cattgaggag       60

gcgctggagc cgggtgcctg ctgtgccacg tgtgtgcagc agggctgcgc ctgcgagggc      120

taccagtact atgactgcct acagggtggc ttcgtgcgcg gccgcgtgcc cgccggtcag      180

tcctattttg tggacttcgg gagcactgag tgctcctgcc caccaggcgg cggcaagatc      240

agctgccagt tcatgctgtg cccggagctg ccgcccaact gcatcgaggc tgtagtggtg      300

gctgacagct gcccacagtg cggccaggtg ggctgcgtcc acgcgggcca caagtacgcc      360

gctggccaca ctgttcacct gccgccctgc cgggcctgcc actgccctga cgccggtgga      420

gagctcatct gctaccagct ccccggttgc cacgggaact tctcagatgc cgaggagggt      480

gaccccgagc gacactacga agacccctac agctatgacc aggaggtggc cgaggtggaa      540

gcagcaacag ccctgggggg tgaggtccag gcgggtgcag tccaggcagg cgcagggggc      600

cccccagctg ctctgggagg tgggagtcag ccactgtcca ccatccaggc acccccctgg      660

ccagctgtcc tccccaggcc cacagcggct gctgccctgg gtcccccagc cccagtgcag      720

gccaaagcta ggagagtgac cgaggacagt gaggaggaag aagaggagga ggaggagaga      780

gaggaaatgg ctgtcactga gcagctggca gcaggtggcc acagggggct ggatgggctg      840

cccactacag ccccagctgg acccagtctt cctatccagg aggagagggc agaagctggg      900

gcaagggcag aagctggggc aaggcctgaa gagaacctca tcctggatgc ccaagccacg      960

tcccgcagca ctgggccgga gggcgtgacg catgcaccga gcctgggcaa ggctgctctc     1020

gtcccaactc aggccgtgcc tggctctccc agggacccag tcaagcccag cccccacaac     1080

atcctgtcca catcactgcc tgatgcagcc tggatcccac ccacccgaga agtgcccagg     1140

aagccgcaag ttctgcccca ttcccacgtg gaggaggaca cagaccccaa ctctgtccat     1200

tctatcccca gaagtagccc tgaaggctcc accaaggacc tgatcgagac ttgctgcgca     1260

gccggacagc agtgggccat tgacaatgac gagtgcctgg agatccctga gagtggcact     1320

gaggacaacg tctgcaggac agcccagagg cactgctgtg tctcctactt gcaggagaag     1380

agctgcatgg ccggcgtcct gggagccaag gagggtgaga cctgtggggc tgaggacaac     1440

gacagctgcg gcatctccct gtacaagcaa tgctgtgact gctgtggcct gggcctccgc     1500

gtgcgggccg agggccagtc gtgtgagtcc aatcctaacc tgggctatcc ctgcaatcat     1560

gtcatgctct cctgctgtga gggtgaagag cctctcatag tacctgaggt tcgccgacct     1620

ccagagcccg cagctgcacc acggagagtt tcagaggcag agatggcggg ccgagaggcc     1680

ctgtcactgg gcacagaggc cgagctgccg aacagcctgc cgggcgatga ccaggatgag     1740

tgccttctcc tcccgggaga gctgtgccag cacctttgca tcaatactgt gggttcttac     1800

cactgtgcct gctttcctgg cttctcactg caggacgatg gccgcacttg ccgcccagag     1860

ggtcaccctc cacagccgga agccccacag gagcctgcac tgaagtcaga attttcccag     1920

gtggcctcta acaccatccc gctgccactg ccgcagccca atacctgcaa agacaatgga     1980

ccctgcaagc aggtgtgcag cactgttggg ggctcagcca tatgctcctg ttttcccggc     2040

tatgccatca tggcggatgg cgtgtcctgt gaagacatca acgagtgtgt gacggacctg     2100

cacacgtgca gccggggcga gcactgtgtg aacacactgg gctccttcca ctgctacaag     2160

gcactcacct gtgagccagg ctatgccctc aaggatggcg agtgcgaaga cgtggatgag     2220

tgtgcgatgg gcacgcacac ctgccagccg ggcttcttgt gccagaacac caagggctcc     2280

ttctactgcc aggccaggca gcgctgcatg gatggcttcc tgcaggatcc tgaaggcaac     2340

tgtgtggaca tcaacgagtg cacgtcactg tccgagccat gtcggccagg cttcagctgc     2400

atcaacacgg tgggctccta cacgtgccag aggaacccgc tgatctgcgc gcgcggctac     2460

cacgccagcg atgatggggc caagtgtgtg gacgtgaatg agtgtgagac aggtgtgcac     2520

cgctgcggtg agggccaagt gtgccacaac ctccctggct cctaccgctg tgactgcaaa     2580

gccggctttc agcgggatgc cttcggccgg ggctgcatcg acgtgaatga gtgctgggcc     2640

tcgccaggcc gcctgtgcca gcacacgtgt gagaacacac tcggctccta ccgctgttcc     2700

tgcgcctccg ggttcctgct agcagcggac ggcaagcgct gtgaagacgt gaatgagtgt     2760

gaggcccagc gctgcagcca ggagtgtgcc aacatctatg gctcctacca gtgctactgc     2820

cgccagggct accagctggc tgaggatggg cacacctgca cagacatcga cgagtgtgct     2880

caaggcgccg gcatcctctg caccttccgc tgtctcaacg tgccagggag ctaccagtgt     2940

gcatgccctg agcagggcta caccatgacg gccaacggga ggtcctgcaa ggacgtggat     3000

gagtgtgcac tgggtaccca caactgttcc gaggctgaga cctgccacaa catccagggt     3060

agcttccgct gcctgcgctt agagtgtcct cccaactatg tccaagtctc caaaacgaag     3120

tgcgagcgca ccacgtgcca tgacttcctg gagtgccaga actcgccagc gcgcatcacg     3180

cactaccagc tcaacttcca gacgggcctc ctggtgcctg cgcatatctt ccgcattggc     3240

cccgcgccag ccttcacggg ggacaccatc gccctgaaca tcatcaaggg caatgaggag     3300

ggctactttg gcacgcgcag gctcaatgcc tacacgggtg tggtctacct gcagcgggcc     3360

gtgctggagc cccgggactt tgccctggac gtggagatga agctctggag gcagggctcc     3420

gtcaccacct tcctggccaa gatgcacatc ttcttcacca cctttgccct g              3471


<210>  3527
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  3527
caggcacagt gcacgaatgg ctttgacctg gatcgccagt caggacagtg tttagatatt       60

gatgaatgcc gaaccatccc cgaggcctgc cgaggagaca tgatgtgtgt taaccaaaat      120

ggcgggtatt tatgcattcc ccggacaaac cctgtgtatc gagggcccta ctcgaacccc      180

tactcgaccc cctactcagg tccgtaccca gcagctgccc caccactctc agctccaaac      240

tatcccacga tctccaggcc tcttatatgc cgctttggat accagatgga tgaaagcaac      300

caatgtgtgg atgtggacga gtgtgcaaca gattcccacc agtgcaaccc cacccagatc      360

tgcatcaata ctgaaggcgg gtacacctgc tcctgcaccg acggatattg gcttctggaa      420

ggccagtgct tagacattga tgaatgtcgc tatggttact gccagcagct ctgtgcgaat      480

gttcctggat cctattcttg tacatgcaac cctggtttta ccctcaatga ggatggaagg      540

tcttgccaag atgtgaacga gtgtgccacc gagaacccct gcgtgcaaac ctgcgtcaac      600

acctacggct ctttcatctg ccgctgtgac ccaggatatg aacttgagga agatggcgtt      660

cattgcagtg atatggacga gtgcagcttc tctgagttcc tctgccaaca tgagtgtgtg      720

aaccagcccg gcacatactt ctgctcctgc cctccaggct acatcctgct ggatgacaac      780

cgaagctgcc aagacatcaa cgaatgtgag cacaggaacc acacgtgcaa cctgcagcag      840

acgtgctaca atttacaagg gggcttcaaa tgcatcgacc ccatccgctg tgaggagcct      900

tatctgagga tcagtgataa ccgctgtatg tgtcctgctg agaaccctgg ctgcagagac      960

cagcccttta ccatcttgta ccgggacatg gacgtggtgt caggacgctc cgttcccgct     1020

gacatcttcc aaatgcaagc cacgacccgc taccctgggg cctattacat tttccagatc     1080

aaatctggga atgagggcag agaattttac atgcggcaaa cgggccccat cagtgccacc     1140

ctggtgatga cacgccccat caaagggccc cgggaaatcc agctggactt ggaaatgatc     1200

actgtcaaca ctgtcatcaa cttcagaggc agctccgtga tccgactgcg gatatatgtg     1260

tcgcagtacc cattc                                                      1275


<210>  3528
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  3528
cagaactgtc tcagcaaaca gcagctcctc tcggccatcc gccagctgca gcagctgctg       60

aagggccagg agacacgctt cgccgagggc atccgccaca tgaagagccg gctggccgcg      120

ctgcagaact ctgtgggcag ggtgggccca gatgcccttc cagtttcctg cccggctctg      180

aacacccccg cagacggcag aaagtttgga agcaagtact tagtggatca cgaagtccat      240

tttacctgca accctgggtt ccggctggtc gggcccagca gcgtggtgtg tcttcccaat      300

ggcacctgga caggggagca gccccactgt agaggtatca gtgaatgctc cagccagcct      360

tgtcaaaatg gtggtacatg tgtagaagga gtcaaccagt acagatgcat ttgtcctcca      420

ggaaggactg ggaaccgctg tcagcatcag gcccagactg ccgcccccga gggcagcgtg      480

gccggcgact ccgccttcag ccgcgcgccg cgctgtgcgc aggtggagcg ggctcagcac      540

tgcagctgcg aggccggatt ccacctgagc ggcgccgccg gcgacagcgt ctgccaggac      600

gtgaacgagt gtgagctcta cgggcaggag gggcgccccc ggctctgcat gcacgcctgc      660

gtgaacaccc cgggctctta ccgttgcacc tgccccggtg gataccgaac tctggctgac      720

gggaagagct gtgaggatgt ggatgaatgt gtgggcctgc agccggtgtg cccccagggg      780

accacatgca tcaacaccgg tggaagcttc cagtgtgtca gccctgagtg ccccgagggc      840

agcggcaatg tgagctacgt gaagacgtct ccattccagt gtgagcggaa cccctgcccc      900

atggacagca ggccctgccg ccatctgccc aagaccatct ccttccatta cctctctctg      960

ccttccaacc tgaagacgcc catcacgctc ttccgcatgg ccacagcctc tgcccccggc     1020

cgagctgggc ccaacagcct gcggtttggg atcgtgggtg ggaacagccg cggccacttt     1080

gtgatgcagc gttcagaccg gcagactggg gatctgatcc ttgtgcagaa cctggagggg     1140

cctcagacgc tggaggtgga cgtcgacatg tcggaatacc tggaccgctc cttccaggcc     1200

aaccacgtgt ccaaggtcac catctttgta tccccctatg acttc                     1245


<210>  3529
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  3529
ggacagcagg acgtgctccg agggcccaac gtgtgcggct ccagattcca ctcctactgc       60

tgccctggat ggaagacgct ccctggagga aaccagtgca ttgtcccgat ttgtagaaat      120

agttgtggag atggattttg ttcccgtcct aacatgtgta cttgttccag tgggcaaata      180

tcatcaacct gtggatcaaa atcaattcag cagtgcagtg tgagatgcat gaatggtggg      240

acctgtgcag atgaccactg ccagtgccag aaaggatata ttggaactta ttgtggacaa      300

cctgtctgtg aaaatggatg tcagaatggt ggacgttgca tcggacccaa ccgctgtgct      360

tgtgtttatg ggttcactgg tccacagtgt gaaagagatt acaggacagg cccgtgtttc      420

actcaggtca acaaccagat gtgccaaggg cagctgacag gcattgtctg cacgaagact      480

ctgtgctgtg ccaccattgg acgggcgtgg ggccatccct gtgagatgtg tccagcccag      540

cctcagccct gccgacgggg tttcatcccc aacatccgca ctggagcttg ccaagatgtt      600

gatgaatgcc aggctatccc agggatatgc caaggaggaa actgtatcaa tacagtgggc      660

tcttttgaat gcagatgccc tgctggtcac aaacagagtg aaactactca gaaatgtgaa      720

gacattgatg agtgcagcat cattcctggg atatgtgaaa ctggtgaatg ttccaacacc      780

gtgggaagct atttttgtgt ttgtccacgt ggatatgtaa cctcaacaga tggctctcga      840

tgcatc                                                                 846


<210>  3530
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3530
agcgcacaca gagaccatca agtaaactta gctacccttg acagcgaagc tctacttacc       60

ttgggactaa atctttcaca cttggggagg gcggagagaa tcttggagtt aagacctgcg      120

ctggagggat tagaaggccg tattagatac gttatagttc gtggtaacga gcaaggattt      180

ttcagaatgc atcacttacg tggggtctct agcttgcaac tgggcagaag aagaccgggg      240

cctggaacgt acagattaga ggttgtgtcc cacatggccg ggccgtgggg tgttcagcca      300

gaggggcagc cagggccatg gggacaagcg ctaaggctaa aagttcagtt gcaattgtta      360


<210>  3531
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  3531
ctacctcaaa aaagaccaca tccccgttgg ctttgggaag ggtcactacc atcccgtacc       60

catcttaggg ccatgggtac acttcgtccg tctagccccc tttgttggcg tgaagagagt      120

tcatttgcag caccgaacag cctgaaaggt tctagattag tatctggcga gcctggtggt      180

gcggtaacga tccaatgcca ctacgcgccg agtagcgtga atagacacca aaggaagtac      240

tggtgtaggc ttgggccgcc cagatggata tgccaaacta tagtgagtac aaatcaatat      300

actcatcata gatatagaga tagagtcgca ttgacagact tcccacaaag aggtttgttt      360

gtcgtcagac tatctcaact gtcacctgat gatattggat gctacctttg tggaattggc      420

agtgaaaaca atatgttatt cctatcaatg aacctaacaa tcagtgccgg acccgcatca      480

actctgccca cggcgactcc agctgctgga gaacttacca tgaggagcta cggtacagcc      540

tcccccgtgg cgaaccgttg gacaccaggg acaacccaga ctctaggcca ggggactgct      600

tgggacacag ttgcatctac cccaggtacc agcaaaacta ccgccagtgc ggagggtaga      660

aggaccccag gtgcgacccg tcccgccgcg ccagggacgg gaagttgggc tgagggcagt      720

gttaaggcac ctgctccaat acctgaaagc cccccaagta agagtaggag tatgtctaac      780

acaactgaag gtgtatggga agggacgcgt tccagcgtta ccaaccgtgc acgtgcgagt      840

aaagatagac gtgaaatgac aacgaccaaa gcagaccgtc cgagggaaga tattgagggt      900

gtgaggatag ccctagacgc ggctaaaaag gttctgggca caatagggcc gcccgcgcta      960

gtatcagaaa ccctagcctg ggaaattctt ccccaagcta ccccggtaag caagcaacaa     1020

tctcaaggga gcattggaga aaccacaccc gcagccggta tgtggacctt gggcactccg     1080

gccgccgatg tctggatcct ggggacaccg gcggctgatg tctggacctc catggaagct     1140

gcctccgggg agggaagcgc ggcgggtgat ctagatgccg caacgggcga taggggccct     1200

caagcaactc taagtcaaac tcccgcggtt ggtccctggg ggccaccagg gaaagagtct     1260

agcgttaaga gaacattccc tgaggacgag tcctctagta ga                        1302


<210>  3532
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  3532
caggaagggg actttcccat gcctttcata tctgccaaat cgagtcctgt gattcccttg       60

gatggatctg tgaaaatcca gtgccaggcc attcgtgaag cttacctgac ccagctgatg      120

atcataaaaa actccacgta ccgagagata ggcagaagac tgaagttttg gaatgagact      180

gatcctgagt tcgtcattga ccacatggac gcaaacaagg cagggcgcta tcagtgccaa      240

tataggatag ggcactacag attccggtac agtgacaccc tggagctggt agtgacaggc      300

ttgtatggca aacccttcct ctctgcagat cggggtctgg tgttgatgcc aggagagaat      360

atttccctca cgtgcagctc agcacacatc ccatttgata gattttcact ggccaaggag      420

ggagaacttt ctctgccaca gcaccaaagt ggggaacacc cggccaactt ctctttgggt      480

cctgtggacc tcaatgtctc agggatctac aggtgctacg gttggtacaa caggagcccc      540

tacctgtggt ccttccccag taatgccttg gagcttgtgg tcacagactc catccaccaa      600

gattacacga cgcagaac                                                    618


<210>  3533
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  3533
gtccctcaga aacctaaggt ctccttgaac cctccatgga atagaatatt taaaggagag       60

aatgtgactc ttacatgtaa tgggaacaat ttctttgaag tcagttccac caaatggttc      120

cacaatggca gcctttcaga agagacaaat tcaagtttga atattgtgaa tgccaaattt      180

gaagacagtg gagaatacaa atgtcagcac caacaagtta atgagagtga acctgtgtac      240

ctggaagtct tcagtgactg gctgctcctt caggcctctg ctgaggtggt gatggagggc      300

cagcccctct tcctcaggtg ccatggttgg aggaactggg atgtgtacaa ggtgatctat      360

tataaggatg gtgaagctct caagtactgg tatgagaacc acaacatctc cattacaaat      420

gccacagttg aagacagtgg aacctactac tgtacgggca aagtgtggca gctggactat      480

gagtctgagc ccctcaacat tactgtaata aaagctccgc gtgagaagta ctggctacaa      540


<210>  3534
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  3534
atggagttgc aggtgtccag cggctttgtg tgcaacacgt gccctgaaaa gtggatcaat       60

ttccaacgga agtgctacta cttcggcaag ggcaccaagc agtgggtcca cgcccggtat      120

gcctgtgacg acatggaagg gcagctggtc agcatccaca gcccggagga gcaggacttc      180

ctgaccaagc atgccagcca caccggctcc tggattggcc ttcggaactt ggacctgaag      240

ggggagttta tctgggtgga tgggagccac gtggactaca gcaactgggc tccaggggag      300

cccaccagcc ggagccaggg cgaggactgc gtgatgatgc ggggctccgg tcgctggaac      360

gacgccttct gcgaccgtaa gctgggcgcc tgggtgtgcg accggctggc cacatgcacg      420

ccgccagcca gcgaaggttc cgcggagtcc atgggacctg attcaagacc agaccctgac      480

ggccgcctgc ccaccccctc tgcccctctc cactct                                516


<210>  3535
<211>  831
<212>  DNA
<213>  Homo Sapiens

<400>  3535
caagtggaca ccacaaaggc agtgatcact ttgcagcctc catgggtcag cgtgttccaa       60

gaggaaaccg taaccttgca ttgtgaggtg ctccatctgc ctgggagcag ctctacacag      120

tggtttctca atggcacagc cactcagacc tcgaccccca gctacagaat cacctctgcc      180

agtgtcaatg acagtggtga atacaggtgc cagagaggtc tctcagggcg aagtgacccc      240

atacagctgg aaatccacag aggctggcta ctactgcagg tctccagcag agtcttcacg      300

gaaggagaac ctctggcctt gaggtgtcat gcgtggaagg ataagctggt gtacaatgtg      360

ctttactatc gaaatggcaa agcctttaag tttttccact ggaattctaa cctcaccatt      420

ctgaaaacca acataagtca caatggcacc taccattgct caggcatggg aaagcatcgc      480

tacacatcag caggaatatc tgtcactgtg aaagagctat ttccagctcc agtgctgaat      540

gcatctgtga catccccact cctggagggg aatctggtca ccctgagctg tgaaacaaag      600

ttgctcttgc agaggcctgg tttgcagctt tacttctcct tctacatggg cagcaagacc      660

ctgcgaggca ggaacacatc ctctgaatac caaatactaa ctgctagaag agaagactct      720

gggttatact ggtgcgaggc tgccacagag gatggaaatg tccttaagcg cagccctgag      780

ttggagcttc aagtgcttgg cctccagtta ccaactcctg tctggtttca t               831


<210>  3536
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3536
caagtggaca ccacaaaggc agtgatcact ttgcagcctc catgggtcag cgtgttccaa       60

gaggaaaccg taaccttgca ctgtgaggtg ctccatctgc ctgggagcag ctccacacag      120

tggtttctca atggcacagc cactcagacc tcgaccccca gctacagaat cacctctgcc      180

agtgtcaatg acagtggtga atacaggtgc cagagaggtc tctcagggcg aagtgacccc      240

atacagctgg aaatccacag aggctggcta ctactgcagg tctccagcag agtcttcatg      300

gaaggagaac ctctggcctt gaggtgtcat gcgtggaagg ataagctggt gtacaatgtg      360

ctttactatc gaaatggcaa agcctttaag tttttccact ggaattctaa cctcaccatt      420

ctgaaaacca acataagtca caatggcacc taccattgct caggcatggg aaagcatcgc      480

tacacatcag caggaatatc acaatacact gtgaaaggcc tccagttacc aactcctgtc      540

tggtttcat                                                              549


<210>  3537
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3537
caagctgctc ccccaaaggc tgtgctgaaa cttgagcccc cgtggatcaa cgtgctccag       60

gaggactctg tgactctgac atgccagggg gctcgcagcc ctgagagcga ctccattcag      120

tggttccaca atgggaatct cattcccacc cacacgcagc ccagctacag gttcaaggcc      180

aacaacaatg acagcgggga gtacacgtgc cagactggcc agaccagcct cagcgaccct      240

gtgcatctga ctgtgctttc cgaatggctg gtgctccaga cccctcacct ggagttccag      300

gagggagaaa ccatcatgct gaggtgccac agctggaagg acaagcctct ggtcaaggtc      360

acattcttcc agaatggaaa atcccagaaa ttctcccatt tggatcccac cttctccatc      420

ccacaagcaa accacagtca cagtggtgat taccactgca caggaaacat aggctacacg      480

ctgttctcat ccaagcctgt gaccatcact gtccaagtgc ccagcatggg cagctcttca      540

ccaatgggg                                                              549


<210>  3538
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3538
acacctgcag ctcccccaaa ggctgtgctg aaactcgagc cccagtggat caacgtgctc       60

caggaggact ctgtgactct gacatgccgg gggactcaca gccctgagag cgactccatt      120

cagtggttcc acaatgggaa tctcattccc acccacacgc agcccagcta caggttcaag      180

gccaacaaca atgacagcgg ggagtacacg tgccagactg gccagaccag cctcagcgac      240

cctgtgcatc tgactgtgct ttctgagtgg ctggtgctcc agacccctca cctggagttc      300

caggagggag aaaccatcgt gctgaggtgc cacagctgga aggacaagcc tctggtcaag      360

gtcacattct tccagaatgg aaaatccaag aaattttccc gttcggatcc caacttctcc      420

atcccacaag caaaccacag tcacagtggt gattaccact gcacaggaaa cataggctac      480

acgctgtact catccaagcc tgtgaccatc actgtccaag ctccc                      525


<210>  3539
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3539
acacctgcag ctcccccaaa ggctgtgctg aaactcgagc cccagtggat caacgtgctc       60

caggaggact ctgtgactct gacatgccgg gggactcaca gccctgagag cgactccatt      120

cagtggttcc acaatgggaa tctcattccc acccacacgc agcccagcta caggttcaag      180

gccaacaaca atgacagcgg ggagtacacg tgccagactg gccagaccag cctcagcgac      240

cctgtgcatc tgactgtgct ttctgagtgg ctggtgctcc agacccctca cctggagttc      300

caggagggag aaaccatcgt gctgaggtgc cacagctgga aggacaagcc tctggtcaag      360

gtcacattct tccagaatgg aaaatccaag aaattttccc gttcggatcc caacttctcc      420

atcccacaag caaaccacag tcacagtggt gattaccact gcacaggaaa cataggctac      480

acgctgtact catccaagcc tgtgaccatc actgtccaag ctccc                      525


<210>  3540
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  3540
acccccgccg ctcccccgaa agcggtttta aagctggaac cgcagtggat caatgtctta       60

caggaagact ccgtgacctt gacttgccgt gggactcact cacccgaaag tgactccatt      120

cagtggttcc ataatggcaa cttaatcccg acacatactc agcctagtta cagatttaag      180

gcgaacaata atgatagtgg agaatatacc tgtcaaacag gtcagacatc actatcagat      240

ccagtacatc ttacagtgtt gtctgagtgg ttggtactac agacaccgca cctagagttc      300

caagaaggtg agacgatagt actgagatgt cattcatgga aagacaaacc tctagtgaag      360

gtgacttttt ttcagaatgg caagagtaag aaattcagca ggagtgaccc caacttctct      420

attccacaag cgaaccacag ccatagtggt gattaccact gcacgggaaa tataggatac      480

accctttatt caagtaagcc tgttacaatt accgtgcagg cccctagttc ttccccgatg      540

gga                                                                    543


<210>  3541
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  3541
ggcatgcgga ctgaagatct cccaaaggct gtggtgttcc tggagcctca atggtacagg       60

gtgctcgaga aggacagtgt gactctgaag tgccagggag cctactcccc tgaggacaat      120

tccacacagt ggtttcacaa tgagagcctc atctcaagcc aggcctcgag ctacttcatt      180

gacgctgcca cagtcgacga cagtggagag tacaggtgcc agacaaacct ctccaccctc      240

agtgacccgg tgcagctaga agtccatatc ggctggctgt tgctccaggc ccctcggtgg      300

gtgttcaagg aggaagaccc tattcacctg aggtgtcaca gctggaagaa cactgctctg      360

cataaggtca catatttaca gaatggcaaa ggcaggaagt attttcatca taattctgac      420

ttctacattc caaaagccac actcaaagac agcggctcct acttctgcag ggggcttgtt      480

gggagtaaaa atgtgtcttc agagactgtg aacatcacca tcactcaagg tttggcagtg      540

tcaaccatct catcattctt tccacctggg taccaa                                576


<210>  3542
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  3542
ggcatgcgga ctgaagatct cccaaaggct gtggtgttcc tggagcctca atggtacagg       60

gtgctcgaga aggacagtgt gactctgaag tgccagggag cctactcccc tgaggacaat      120

tccacacagt ggtttcacaa tgagagcctc atctcaagcc aggcctcgag ctacttcatt      180

gacgctgcca cagttgacga cagtggagag tacaggtgcc agacaaacct ctccaccctc      240

agtgacccgg tgcagctaga agtccatatc ggctggctgt tgctccaggc ccctcggtgg      300

gtgttcaagg aggaagaccc tattcacctg aggtgtcaca gctggaagaa cactgctctg      360

cataaggtca catatttaca gaatggcaaa ggcaggaagt attttcatca taattctgac      420

ttctacattc caaaagccac actcaaagac agcggctcct acttctgcag ggggcttgtt      480

gggagtaaaa atgtgtcttc agagactgtg aacatcacca tcactcaagg tttgtcagtg      540

tcaaccatct catcattctt tccacctggg taccaa                                576


<210>  3543
<211>  822
<212>  DNA
<213>  Homo Sapiens

<400>  3543
gcagaaagcc acctctccct cctgtaccac cttaccgcgg tgtcctcgcc tgccccgggg       60

actcctgcct tctgggtgtc cggctggctg ggcccgcagc agtacctgag ctacaatagc      120

ctgcggggcg aggcggagcc ctgtggagct tgggtctggg aaaaccaggt gtcctggtat      180

tgggagaaag agaccacaga tctgaggatc aaggagaagc tctttctgga agctttcaaa      240

gctttggggg gaaaaggtcc ctacactctg cagggcctgc tgggctgtga actgggccct      300

gacaacacct cggtgcccac cgccaagttc gccctgaacg gcgaggagtt catgaatttc      360

gacctcaagc agggcacctg gggtggggac tggcccgagg ccctggctat cagtcagcgg      420

tggcagcagc aggacaaggc ggccaacaag gagctcacct tcctgctatt ctcctgcccg      480

caccgcctgc gggagcacct ggagaggggc cgcggaaacc tggagtggaa ggagcccccc      540

tccatgcgcc tgaaggcccg acccagcagc cctggctttt ccgtgcttac ctgcagcgcc      600

ttctccttct accctccgga gctgcaactt cggttcctgc ggaatgggct ggccgctggc      660

accggccagg gtgacttcgg ccccaacagt gacggatcct tccacgcctc gtcgtcacta      720

acagtcaaaa gtggcgatga gcaccactac tgctgcattg tgcagcacgc ggggctggcg      780

cagcccctca gggtggagct ggaatctcca gccaagtcct cc                         822


<210>  3544
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  3544
aggatcctcc cagaagtaaa ggtagagggg gagctgggcg gatcagttac catcaagtgc       60

ccacttcctg aaatgcatgt gaggatatat ctgtgccggg agatggctgg atctggaaca      120

tgtggtaccg tggtatccac caccaacttc atcaaggcag aatacaaggg ccgagttact      180

ctgaagcaat acccacgcaa gaatctgttc ctagtggagg taacacagct gacagaaagt      240

gacagcggag tctatgcctg cggagcgggc atgaacacag accggggaaa gacccagaaa      300

gtcaccctga atgtccacag tgaatacgag ccatcatggg aagagcagcc aatgcctgag      360

actccaaaat ggtttcatct gccctatttg ttccagatgc ctgcatatgc cagttcttcc      420

aaattcgtaa ccagagttac cacaccagct caaaggggca aggtccctcc agttcaccac      480

tcctccccca ccacccaaat cacccaccgc cctcgagtgt ccagagcatc ttcagtagca      540

ggtgacaagc cccgaacctt cctgccatcc actacagcct caaaaatctc agctctggag      600

gggctgctca agccccagac gcccagctac aaccaccaca ccaggctgca caggcagaga      660

gcactggact atggctcaca gtctgggagg gaaggccaag ga                         702


<210>  3545
<211>  873
<212>  DNA
<213>  Homo Sapiens

<400>  3545
gccgagctgt ttttgatagc cagcccctcc catcccacag aggggagccc agtgaccctg       60

acgtgtaaga tgccctttct acagagttca gatgcccagt tccagttctg ctttttcaga      120

gacacccggg ccttgggccc aggctggagc agctccccca agctccagat cgctgccatg      180

tggaaagaag acacagggtc atactggtgc gaggcacaga caatggcgtc caaagtcttg      240

aggagcagga gatcccagat aaatgtgcac agggtccctg tcgctgatgt gagcttggag      300

actcagcccc caggaggaca ggtgatggag ggagacaggc tggtcctcat ctgctcagtt      360

gctatgggca caggagacat caccttcctt tggtacaaag gggctgtagg tttaaacctt      420

cagtcaaaga cccagcgttc actgacagca gagtatgaga ttccttcagt gagggagagt      480

gatgctgagc aatattactg tgtagctgaa aatggctatg gtcccagccc cagtgggctg      540

gtgagcatca ctgtcagaat cccggtgtct cgcccaatcc tcatgctcag ggctcccagg      600

gcccaggctg cagtggagga tgtgctggag cttcactgtg aggccctgag aggctctcct      660

ccgatcctgt actggtttta tcacgaggat atcaccctgg ggagcaggtc ggccccctct      720

ggaggaggag cctccttcaa cctttccctg actgaagaac attctggaaa ctactcctgt      780

gaggccaaca atggcctggg ggcccagcgc agtgaggcgg tgacactcaa cttcacagtg      840

cctactgggg ccagaagcaa tcatcttacc tca                                   873


<210>  3546
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  3546
ctgacccttg tggcgccctc ttctgtcttc gaaggagaca gcatcgttct gaaatgccag       60

ggagaacaga actggaaaat tcagaagatg gcttaccata aggataacaa agagttatct      120

gttttcaaaa aattctcaga tttccttatc caaagtgcag ttttaagtga cagtggtaac      180

tatttctgta gtaccaaagg acaactcttt ctctgggata aaacttcaaa tatagtaaag      240

ataaaagtcc aaggacctga tggctataga agagacctca tgacagctgg agtt            294


<210>  3547
<211>  1668
<212>  DNA
<213>  Homo Sapiens

<400>  3547
ggggtggccc caaaagctgt acttctcctc aatcctccat ggtccacagc cttcaaagga       60

gaaaaagtgg ctctcatatg cagcagcata tcacattccc tagcccaggg agacacatat      120

tggtatcacg atgagaagtt gttgaaaata aaacatgaca agatccaaat tacagagcct      180

ggaaattacc aatgtaagac ccgaggatcc tccctcagtg atgccgtgca tgtggaattt      240

tcacctgact ggctgatcct gcaggcttta catcctgtct ttgaaggaga caatgtcatt      300

ctgagatgtc aggggaaaga caacaaaaac actcatcaaa aggtttacta caaggatgga      360

aaacagcttc ctaatagtta taatttagag aagatcacag tgaattcagt ctccagggat      420

aatagcaaat atcattgtac tgcttatagg aagttttaca tacttgacat tgaagtaact      480

tcaaaacccc taaatatcca agttcaagag ctgtttctac atcctgtgct gagagccagc      540

tcttccacgc ccatagaggg gagtcccatg accctgacct gtgagaccca gctctctcca      600

cagaggccag atgtccagct gcaattctcc ctcttcagag atagccagac cctcggattg      660

ggctggagca ggtcccccag actccagatc cctgccatgt ggactgaaga ctcagggtct      720

tactggtgtg aggtggagac agtgactcac agcatcaaaa aaaggagcct gagatctcag      780

atacgtgtac agagagtccc tgtgtctaat gtgaatctag agatccggcc caccggaggg      840

cagctgattg aaggagaaaa tatggtcctt atttgctcag tagcccaggg ttcagggact      900

gtcacattct cctggcacaa agaaggaaga gtaagaagcc tgggtagaaa gacccagcgt      960

tccctgttgg cagagctgca tgttctcacc gtgaaggaga gtgatgcagg gagatactac     1020

tgtgcagctg ataacgttca cagccccatc ctcagcacgt ggattcgagt caccgtgaga     1080

attccggtat ctcaccctgt cctcaccttc agggctccca gggcccacac tgtggtgggg     1140

gacctgctgg agcttcactg tgagtccctg agaggctctc ccccgatcct gtaccgattt     1200

tatcatgagg atgtcaccct ggggaacagc tcagccccct ctggaggagg agcctccttc     1260

aacctctctc tgactgcaga acattctgga aactactcct gtgatgcaga caatggcctg     1320

ggggcccagc acagtcatgg agtgagtctc agggtcacag ttccggtgtc tcgccccgtc     1380

ctcaccctca gggctcccgg ggcccaggct gtggtggggg acctgctgga gcttcactgt     1440

gagtccctga gaggctcctt cccgatcctg tactggtttt atcacgagga tgacaccttg     1500

gggaacatct cggcccactc tggaggaggg gcatccttca acctctctct gactacagaa     1560

cattctggaa actactcatg tgaggctgac aatggcctgg gggcccagca cagtaaagtg     1620

gtgacactca atgttacagg aacttccagg aacagaacag gccttacc                  1668


<210>  3548
<211>  1104
<212>  DNA
<213>  Homo Sapiens

<400>  3548
gcacacaaac ctgtgatttc cgtccatcct ccatggacca cattcttcaa aggagagaga       60

gtgactctga cttgcaatgg atttcagttc tatgcaacag agaaaacaac atggtatcat      120

cggcactact ggggagaaaa gttgaccctg accccaggaa acaccctcga ggttcgggaa      180

tctggactgt acagatgcca ggcccggggc tccccacgaa gtaaccctgt gcgcttgctc      240

ttttcttcag actccttaat cctgcaggca ccatattctg tgtttgaagg tgacacattg      300

gttctgagat gccacagaag aaggaaagag aaattgactg ctgtgaaata tacttggaat      360

ggaaacattc tttccatttc taataaaagc tgggatcttc ttatcccaca agcaagttca      420

aataacaatg gcaattatcg atgcattgga tatggagatg agaatgatgt atttagatca      480

aatttcaaaa taattaaaat tcaagaacta tttccacatc cagagctgaa agctacagac      540

tctcagccta cagaggggaa ttctgtaaac ctgagctgtg aaacacagct tcctccagag      600

cggtcagaca ccccacttca cttcaacttc ttcagagatg gcgaggtcat cctgtcagac      660

tggagcacgt acccggaact ccagctccca accgtctgga gagaaaactc aggatcctat      720

tggtgtggtg ctgaaacagt gaggggtaac atccacaagc acagtccctc gctacagatc      780

catgtgcagc ggatccctgt gtctggggtg ctcctggaga cccagccctc agggggccag      840

gctgttgaag gggagatgct ggtccttgtc tgctccgtgg ctgaaggcac aggggatacc      900

acattctcct ggcaccgaga ggacatgcag gagagtctgg ggaggaaaac tcagcgttcc      960

ctgagagcag agctggagct ccctgccatc agacagagcc atgcaggggg atactactgt     1020

acagcagaca acagctacgg ccctgtccag agcatggtgc tgaatgtcac tgtgagagag     1080

accccaggca acagagatgg cctt                                            1104


<210>  3549
<211>  2508
<212>  DNA
<213>  Homo Sapiens

<400>  3549
cagtttgcaa ggacacccag gcccattatt ttcctccagc ctccatggac cacagtcttc       60

caaggagaga gagtgaccct cacttgcaag ggatttcgct tctactcacc acagaaaaca      120

aaatggtacc atcggtacct tgggaaagaa atactaagag aaaccccaga caatatcctt      180

gaggttcagg aatctggaga gtacagatgc caggcccagg gctcccctct cagtagccct      240

gtgcacttgg atttttcttc agcttcgctg atcctgcaag ctccactttc tgtgtttgaa      300

ggagactctg tggttctgag gtgccgggca aaggcggaag taacactgaa taatactatt      360

tacaagaatg ataatgtcct ggcattcctt aataaaagaa ctgacttcca tattcctcat      420

gcatgtctca aggacaatgg tgcatatcgc tgtactggat ataaggaaag ttgttgccct      480

gtttcttcca atacagtcaa aatccaagtc caagagccat ttacacgtcc agtgctgaga      540

gccagctcct tccagcccat cagcgggaac ccagtgaccc tgacctgtga gacccagctc      600

tctctagaga ggtcagatgt cccgctccgg ttccgcttct tcagagatga ccagaccctg      660

ggattaggct ggagtctctc cccgaatttc cagattactg ccatgtggag taaagattca      720

gggttctact ggtgtaaggc agcaacaatg cctcacagca tcatatctga cagcccgaga      780

tcctggatac aggtgcagat ccctgcatct catcctgtcc tcactctcag ccctgaaaag      840

gctctgaatt ttgagggaac caaggtgaca cttcactgtg aaacccagga agattctctg      900

cgcactttgt acaggtttta tcatgagggt gtccccctga ggcacaagtc agtccgctgt      960

gaaaggggag catccatcag cttctcactg actacagaga attcagggaa ctactactgc     1020

acagctgaca atggccttgg cgccaagccc agtaaggctg tgagcctctc agtcactgtt     1080

cccgtgtctc atcctgtcct caacctcagc tctcctgagg acctgatttt tgagggagcc     1140

aaggtgacac ttcactgtga agcccagaga ggttcactcc ccatcctgta ccagtttcat     1200

catgaggatg ctgccctgga gcgtaggtcg gccaactctg caggaggagt ggccatcagc     1260

ttctctctga ctgcagagca ttcagggaac tactactgca cagctgacaa tggctttggc     1320

ccccagcgca gtaaggcggt gagcctctcc atcactgtcc ctgtgtctca tcctgtcctc     1380

accctcagct ctgctgaggc cctgactttt gaaggagcca ctgtgacact tcactgtgaa     1440

gtccagagag gttccccaca aatcctatac cagttttatc atgaggacat gcccctgtgg     1500

agcagctcaa caccctctgt gggaagagtg tccttcagct tctctctgac tgaaggacat     1560

tcagggaatt actactgcac agctgacaat ggctttggtc cccagcgcag tgaagtggtg     1620

agcctttttg tcactgttcc agtgtctcgc cccatcctca ccctcagggt tcccagggcc     1680

caggctgtgg tgggggacct gctggagctt cactgtgagg ccccgagagg ctctccccca     1740

atcctgtact ggttttatca tgaggatgtc accctgggga gcagctcagc cccctctgga     1800

ggagaagctt ctttcaacct ctctctgact gcagaacatt ctggaaacta ctcatgtgag     1860

gccaacaatg gcctagtggc ccagcacagt gacacaatat cactcagtgt tatagttcca     1920

gtatctcgtc ccatcctcac cttcagggct cccagggccc aggctgtggt gggggacctg     1980

ctggagcttc actgtgaggc cctgagaggc tcctccccaa tcctgtactg gttttatcat     2040

gaagatgtca ccctgggtaa gatctcagcc ccctctggag gaggggcctc cttcaacctc     2100

tctctgacta cagaacattc tggaatctac tcctgtgagg cagacaatgg tctggaggcc     2160

cagcgcagtg agatggtgac actgaaagtt gcagttccgg tgtctcgccc ggtcctcacc     2220

ctcagggctc ccgggaccca tgctgcggtg ggggacctgc tggagcttca ctgtgaggcc     2280

ctgagaggct ctcccctgat cctgtaccgg ttttttcatg aggatgtcac cctaggaaat     2340

aggtcgtccc cctctggagg agcgtcctta aacctctctc tgactgcaga gcactctgga     2400

aactactcct gtgaggccga caatggcctc ggggcccagc gcagtgagac agtgacactt     2460

tatatcacag ggctgaccgc gaacagaagt ggcccttttg ccacagga                  2508


<210>  3550
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  3550
ctgtacctac aagcatggcc aaaccctgtg tttgaaggag acgcactgac actacgttgt       60

caggggtgga agaacactcc cctttctcag gttaaatttt atagggacgg caaattccta      120

cacttttcca aggagaacca gacattgagt atgggggcag ctacagttca gagtaggggt      180

caatacagtt gcagcgggca ggtgatgtac attccgcaga cctttaccca aacgtctgaa      240

acagctatgg tccaggttca ggaattgttt cctccaccag tattatcagc aatccccagc      300

ccggagccaa gggaagggtc tctggtgacc cttcgttgcc aaacgaaatt gcatccactt      360

cgttcagcgc tgagattgct gttctcattt cataaagatg gtcatacatt gcaggaccgt      420

gggccacacc ccgagctatg tatcccgggt gctaaagagg gggactccgg tttgtattgg      480

tgtgaagtag ccccagaagg cggacaggtc cagaaacaat ccccgcagct tgaagttcgt      540

gtacaggctc cagtgtcacg tccagtcctg actttgcacc acggccccgc agaccctgca      600

gtaggtgata tggtccaact tttgtgtgag gcccagcgtg gcagtccacc aatactgtac      660

tccttctatc tggatgagaa aatcgtgggt aatcactctg cgccatgcgg gggcacgacc      720

agtcttctgt ttccagtaaa atctgagcaa gatgctggga attactcttg tgaagctgag      780

aacagtgtct ctagggagag gtctgaacca aaaaagctat cattaaaggg gtcccaggtg      840

ctttttacgc ccgcctcaaa ctgg                                             864


<210>  3551
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  3551
gcgacgttgg aaaaaccgat tttgtcactt cacccaccgt ggacgaccat tttcaaggga       60

gaaagagtta cgctaaagtg tgatggctac catcctttgc ttctagagtt acagcccatt      120

agtacgctat ggtatctagg ccaccttctg ttaccctccc acaaaaagag cattgaggtg      180

cagacgcccg gagtatatcg ttgtcagact aggggagcgc cggtatctga tccaatacat      240

ctgtccgtaa gtaacgattg gttaatacta caggttcctt acgcaccggt ctttgagggt      300

gaacctcttg tattacgttg caggggttgg tatgacaagg tcgtgtataa actgcactat      360

tatcacgacg gacaagcagt tagatatttc cactcttccg caaactatac cgttttacag      420

gccagagcta gtgatagcgg acgttaccaa tgctccggca caatgcgtat ccctgtcgag      480

agtgccccaa tgttttcagc aaaagtagca gtcactgtac aggagttatt ccgtgcacca      540

gttttaaggg ttatgggacc cagagaggcg aggggagccg cattaggggg tgtagtactt      600

aggtgcgata cacgtctaca cccgcagaaa agagatactc cactgcaatt tgctttttac      660

aagtatagtc gtgcggttag gagattcgac tggggggcag agtacactgt tccggaaccc      720

gaggtggaag aactggaatc atattggtgc gaggctgcca cggctactag atcagtccgt      780

aaaaggtctc cgtggttgca gctacccggc cctggaagtc ctttggaccc ggcatctaca      840

accgcgccgg ccccatgggc tgccgcccta gctcccggaa acaggccact ttcctttcgt      900

aagccgccgg tgtccagatc cgtccccttg gttacgtcag ttagaaatac cacaagtact      960

gggttgcagt ttcccgccag cggtgccccg actgcaggtc ctcccgcgtg cgcgcctccg     1020

accccgctgg aacaatctgc aggagcctta aaaccagacg tggacctttt gctgagagag     1080

atgcaacttc ttaaggggct tttgtccaga gttgtattgg agcttaaaga acctcaggca     1140

ttaagggaat taagggggac ccctgagacg cccactagtc atttcgctgt ttctcccgga     1200

acacctgaga caactccggt tgaatca                                         1227


<210>  3552
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  3552
gccagttttg agacgctgca gtgtgaggga cctgtctgca ctgaggagag cagctgccac       60

acggaggatg acttgactga tgcaagggaa gctggcttcc aggtcaaggc ctacactttc      120

agtgaaccct tccacctgat tgtgtcctat gactggctga tcctccaagg tccagccaag      180

ccagtttttg aaggggacct gctggttctg cgctgccagg cctggcaaga ctggccactg      240

actcaggtga ccttctaccg agatggctca gctctgggtc cccccgggcc taacagggaa      300

ttctccatca ccgtggtaca aaaggcagac agcgggcact accactgcag tggcatcttc      360

cagagccctg gtcctgggat cccagaaaca gcatctgttg tggctatcac agtccaagaa      420

ctgtttccag cgccaattct cagagctgta ccctcagctg aaccccaagc aggaagcccc      480

atgaccctga gttgtcagac aaagttgccc ctgcagaggt cagctgcccg cctcctcttc      540

tccttctaca aggatggaag gatagtgcaa agcagggggc tctcctcaga attccagatc      600

cccacagctt cagaagatca ctccgggtca tactggtgtg aggcagccac tgaggacaac      660

caagtttgga aacagagccc ccagctagag atcagagtgc agggtgcttc cagctctgct      720

gcacctccca cattgaatcc agctcctcag aaatcagctg ctccaggaac tgctcctgag      780

gaggcccctg ggcctctgcc tccgccgcca accccatctt ctgaggatcc aggcttttct      840

tctcctctgg ggatgccaga tcctcatctg tatcaccaga tgggccttct tctcaaacac      900

atgcaggatg tgagagtcct cctcggtcac ctgctcatgg agttgaggga attatctggc      960

caccagaagc ctgggaccac aaaggctact gctgaa                                996


<210>  3553
<211>  420
<212>  DNA
<213>  Homo Sapiens

<400>  3553
tttaatctgc ctccagggaa ttacaagaag cccaaactcc tctactgtag caacgggggc       60

cacttcctga ggatccttcc ggatggcaca gtggatggga caagggacag gagcgaccag      120

cacattcagc tgcagctcag tgcggaaagc gtgggggagg tgtatataaa gagtaccgag      180

actggccagt acttggccat ggacaccgac gggcttttat acggctcaca gacaccaaat      240

gaggaatgtt tgttcctgga aaggctggag gagaaccatt acaacaccta tatatccaag      300

aagcatgcag agaagaattg gtttgttggc ctcaagaaga atgggagctg caaacgcggt      360

cctcggactc actatggcca gaaagcaatc ttgtttctcc ccctgccagt ctcttctgat      420


<210>  3554
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  3554
caagcccttg gtcaggacat ggtgtcacca gaggccacca actcttcttc ctcctccttc       60

tcctctcctt ccagcgcggg aaggcatgtg cggagctaca atcaccttca aggagatgtc      120

cgctggagaa agctattctc tttcaccaag tactttctca agattgagaa gaacgggaag      180

gtcagcggga ccaagaagga gaactgcccg tacagcatcc tggagataac atcagtagaa      240

atcggagttg ttgccgtcaa agccattaac agcaactatt acttagccat gaacaagaag      300

gggaaactct atggctcaaa agaatttaac aatgactgta agctgaagga gaggatagag      360

gaaaatggat acaataccta tgcatcattt aactggcagc ataatgggag gcaaatgtat      420

gtggcattga atggaaaagg agctccaagg agaggacaga aaacacgaag gaaaaacacc      480

tctgctcact ttcttccaat ggtggtacac tca                                   513


<210>  3555
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3555
atggcagagg tggggggcgt cttcgcctcc ttggactggg atctacacgg cttctcctcg       60

tctctgggga acgtgccctt agctgactcc ccaggtttcc tgaacgagcg cctgggccaa      120

atcgagggga agctgcagcg tggctcaccc acagacttcg cccacctgaa ggggatcctg      180

cggcgccgcc agctctactg ccgcaccggc ttccacctgg agatcttccc caacggcacg      240

gtgcacggga cccgccacga ccacagccgc ttcggaatcc tggagtttat cagcctggct      300

gtggggctga tcagcatccg gggagtggac tctggcctgt acctaggaat gaatgagcga      360

ggagaactct atgggtcgaa gaaactcaca cgtgaatgtg ttttccggga acagtttgaa      420

gaaaactggt acaacaccta tgcctcaacc ttgtacaaac attcggactc agagagacag      480

tattacgtgg ccctgaacaa agatggctca ccccgggagg gatacaggac taaacgacac      540

cagaaattca ctcacttttt acccaggcct gtagatcctt ctaagttgcc ctccatgtcc      600

agagacctct ttcactatag g                                                621


<210>  3556
<211>  582
<212>  DNA
<213>  Homo Sapiens

<400>  3556
actcaggggg agaatcaccc gtctcctaat tttaaccagt acgtgaggga ccagggcgcc       60

atgaccgacc agctgagcag gcggcagatc cgcgagtacc aactctacag caggaccagt      120

ggcaagcacg tgcaggtcac cgggcgtcgc atctccgcca ccgccgagga cggcaacaag      180

tttgccaagc tcatagtgga gacggacacg tttggcagcc gggttcgcat caaaggggct      240

gagagtgaga agtacatctg tatgaacaag aggggcaagc tcatcgggaa gcccagcggg      300

aagagcaaag actgcgtgtt cacggagatc gtgctggaga acaactatac ggccttccag      360

aacgcccggc acgagggctg gttcatggcc ttcacgcggc aggggcggcc ccgccaggct      420

tcccgcagcc gccagaacca gcgcgaggcc cacttcatca agcgcctcta ccaaggccag      480

ctgcccttcc ccaaccacgc cgagaagcag aagcagttcg agtttgtggg ctccgccccc      540

acccgccgga ccaagcgcac acggcggccc cagcccctca cg                         582


<210>  3557
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  3557
gaggagaacg tggacttccg catccacgtg gagaaccaga cgcgggctcg ggacgatgtg       60

agccgtaagc agctgcggct gtaccagctc tacagccgga ccagtgggaa acacatccag      120

gtcctgggcc gcaggatcag tgcccgcggc gaggatgggg acaagtatgc ccagctccta      180

gtggagacag acaccttcgg tagtcaagtc cggatcaagg gcaaggagac ggaattctac      240

ctgtgcatga accgcaaagg caagctcgtg gggaagcccg atggcaccag caaggagtgt      300

gtgttcatcg agaaggttct ggagaacaac tacacggccc tgatgtcggc taagtactcc      360

ggctggtacg tgggcttcac caagaagggg cggccgcgga agggccccaa gacccgggag      420

aaccagcagg acgtgcattt catgaagcgc taccccaagg ggcagccgga gcttcagaag      480

cccttcaagt acacgacggt gaccaagagg tcccgtcgga tccggcccac acaccctgcc      540


<210>  3558
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  3558
ctcgccttct cggacgcggg gccccacgtg cactacggct ggggcgaccc catccgcctg       60

cggcacctgt acacctccgg cccccacggg ctctccagct gcttcctgcg catccgtgcc      120

gacggcgtcg tggactgcgc gcggggccag agcgcgcaca gtttgctgga gatcaaggca      180

gtcgctctgc ggaccgtggc catcaagggc gtgcacagcg tgcggtacct ctgcatgggc      240

gccgacggca agatgcaggg gctgcttcag tactcggagg aagactgtgc tttcgaggag      300

gagatccgcc cagatggcta caatgtgtac cgatccgaga agcaccgcct cccggtctcc      360

ctgagcagtg ccaaacagcg gcagctgtac aagaacagag gctttcttcc actctctcat      420

ttcctgccca tgctgcccat ggtcccagag gagcctgagg acctcagggg ccacttggaa      480

tctgacatgt tctcttcgcc cctggagacc gacagcatgg acccatttgg gcttgtcacc      540

ggactggagg ccgtgaggag tcccagcttt gagaag                                576


<210>  3559
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  3559
atggctccct tagccgaagt cgggggcttt ctgggcggcc tggagggctt gggccagcag       60

gtgggttcgc atttcctgtt gcctcctgcc ggggagcggc cgccgctgct gggcgagcgc      120

aggagcgcgg cggagcggag cgcccgcggc gggccggggg ctgcgcagct ggcgcacctg      180

cacggcatcc tgcgccgccg gcagctctat tgccgcaccg gcttccacct gcagatcctg      240

cccgacggca gcgtgcaggg cacccggcag gaccacagcc tcttcggtat cttggaattc      300

atcagtgtgg cagtgggact ggtcagtatt agaggtgtgg acagtggtct ctatcttgga      360

atgaatgaca aaggagaact ctatggatca gagaaactta cttccgaatg catctttagg      420

gagcagtttg aagagaactg gtataacacc tattcatcta acatatataa acatggagac      480

actggccgca ggtattttgt ggcacttaac aaagacggaa ctccaagaga tggcgccagg      540

tccaagaggc atcagaaatt tacacatttc ttacctagac cagtggatcc agaaagagtt      600

ccagaattgt acaaggacct actgatgtac act                                   633


<210>  3560
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  3560
caccccatcc ctgactccag tcctctcctg caattcgggg gccaagtccg gcagcggtac       60

ctctacacag atgatgccca gcagacagaa gcccacctgg agatcaggga ggatgggacg      120

gtggggggcg ctgctgacca gagccccgaa agtctcctgc agctgaaagc cttgaagccg      180

ggagttattc aaatcttggg agtcaagaca tccaggttcc tgtgccagcg gccagatggg      240

gccctgtatg gatcgctcca ctttgaccct gaggcctgca gcttccggga gctgcttctt      300

gaggacggat acaatgttta ccagtccgaa gcccacggcc tcccgctgca cctgccaggg      360

aacaagtccc cacaccggga ccctgcaccc cgaggaccag ctcgcttcct gccactacca      420

ggcctgcccc ccgcaccccc ggagccaccc ggaatcctgg ccccccagcc ccccgatgtg      480

ggctcctcgg accctctgag catggtggga ccttcccagg gccgaagccc cagctacgct      540

tcc                                                                    543


<210>  3561
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  3561
tatcccaatg cctccccact gctcggctcc agctggggtg gcctgatcca cctgtacaca       60

gccacagcca ggaacagcta ccacctgcag atccacaaga atggccatgt ggatggcgca      120

ccccatcaga ccatctacag tgccctgatg atcagatcag aggatgctgg ctttgtggtg      180

attacaggtg tgatgagcag aagatacctc tgcatggatt tcagaggcaa catttttgga      240

tcacactatt tcgacccgga gaactgcagg ttccaacacc agacgctgga aaacgggtac      300

gacgtctacc actctcctca gtatcacttc ctggtcagtc tgggccgggc gaagagagcc      360

ttcctgccag gcatgaaccc acccccgtac tcccagttcc tgtcccggag gaacgagatc      420

cccctaattc acttcaacac ccccatacca cggcggcaca cccggagcgc cgaggacgac      480

tcggagcggg accccctgaa cgtgctgaag ccccgggccc ggatgacccc ggccccggcc      540

tcctgttcac aggagctccc gagcgccgag gacaacagcc cgatggccag tgacccatta      600

ggggtggtca ggggcggtcg agtgaacacg cacgctgggg gaacgggccc ggaaggctgc      660

cgccccttcg ccaagttcat c                                                681


<210>  3562
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  3562
gcagcgggcc ctggggcgcg gttgcggcgc gatgcgggcg gccgtggcgg cgtctacgag       60

caccttggcg gggcgccccg gcgccgcaag ctctactgcg ccacgaagta ccacctccag      120

ctgcacccga gcggccgcgt caacggcagc ctggagaaca gcgcctacag tattttggag      180

ataacggcag tggaggtggg cattgtggcc atcaggggtc tcttctccgg gcggtacctg      240

gccatgaaca agaggggacg actctatgct tcggagcact acagcgccga gtgcgagttt      300

gtggagcgga tccacgagct gggctataat acgtatgcct cccggctgta ccggacggtg      360

tctagtacgc ctggggcccg ccggcagccc agcgccgaga gactgtggta cgtgtctgtg      420

aacggcaagg gccggccccg caggggcttc aagacccgcc gcacacagaa gtcctccctg      480

ttcctgcccc gcgtgctgga ccacagggac cacgagatgg tgcggcagct acagagtggg      540

ctgcccagac cccctggtaa gggggtccag ccccgacggc ggcggcagaa gcagagcccg      600

gataacctgg agccctctca cgttcaggct tcgagactgg gctcccagct ggaggccagt      660

gcgcac                                                                 666


<210>  3563
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  3563
cacggggaga agcgtctcgc ccccaaaggg caacccggac ccgctgccac tgataggaac       60

cctagaggct ccagcagcag acagagcagc agtagcgcta tgtcttcctc ttctgcctcc      120

tcctcccccg cagcttctct gggcagccaa ggaagtggct tggagcagag cagtttccag      180

tggagcccct cggggcgccg gaccggcagc ctctactgca gagtgggcat cggtttccat      240

ctgcagatct acccggatgg caaagtcaat ggatcccacg aagccaatat gttaagtgtt      300

ttggaaatat ttgctgtgtc tcaggggatt gtaggaatac gaggagtttt cagcaacaaa      360

tttttagcga tgtcaaaaaa aggaaaactc catgcaagtg ccaagttcac agatgactgc      420

aagttcaggg agcgttttca agaaaatagc tataatacct atgcctcagc aatacataga      480

actgaaaaaa cagggcggga gtggtatgtg gccctgaata aaagaggaaa agccaaacga      540

gggtgcagcc cccgggttaa accccagcat atctctaccc attttctgcc aagattcaag      600

cagtcggagc agccagaact ttctttcacg gttactgttc ctgaaaagaa aaagccacct      660

agccctatca agccaaagat tcccctttct gcacctcgga aaaataccaa ctcagtgaaa      720

tacagactca agtttcgctt tgga                                             744


<210>  3564
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  3564
tcgcctgcag gcacccgtgc caacaacacg ctgctggact cgaggggctg gggcaccctg       60

ctgtccaggt ctcgcgcggg gctagctgga gagattgccg gggtgaactg ggaaagtggc      120

tatttggtgg ggatcaagcg gcagcggagg ctctactgca acgtgggcat cggctttcac      180

ctccaggtgc tccccgacgg ccggatcagc gggacccacg aggagaaccc ctacagcctg      240

ctggaaattt ccaccgtgga gcgaggcgtg gtgagtctct ttggagtgag aagtgccctc      300

ttcgtcgcca tgaacagtaa aggaagattg tacgcaacgc ccagcttcca agaagaatgc      360

aagttcagag aaaccctcct gcccaacaat tacaatgcct acgagtcaga cttgtaccaa      420

gggacctaca ttgccctgag caaatacgga cgggtaaagc ggggcagcaa ggtgtccccg      480

atcatgactg tcactcattt ccttcccagg atc                                   513


<210>  3565
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  3565
tgcaatgaca tgactccaga gcaaatggct acaaatgtga actgttccag ccctgagcga       60

cacacaagaa gttatgatta catggaagga ggggatataa gagtgagaag actcttctgt      120

cgaacacagt ggtacctgag gatcgataaa agaggcaaag taaaagggac ccaagagatg      180

aagaataatt acaatatcat ggaaatcagg acagtggcag ttggaattgt ggcaatcaaa      240

ggggtggaaa gtgaattcta tcttgcaatg aacaaggaag gaaaactcta tgcaaagaaa      300

gaatgcaatg aagattgtaa cttcaaagaa ctaattctgg aaaaccatta caacacatat      360

gcatcagcta aatggacaca caacggaggg gaaatgtttg ttgccttaaa tcaaaagggg      420

attcctgtaa gaggaaaaaa aacgaagaaa gaacaaaaaa cagcccactt tcttcctatg      480

gcaataact                                                              489


<210>  3566
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  3566
ttaggtgaag ttgggaacta tttcggtgtg caggatgcgg taccgtttgg gaatgtgccc       60

gtgttgccgg tggacagccc ggttttgtta agtgaccacc tgggtcagtc cgaagcaggg      120

gggctcccca ggggacccgc agtcacggac ttggatcatt taaaggggat tctcaggcgg      180

aggcagctat actgcaggac tggatttcac ttagaaatct tccccaatgg tactatccag      240

ggaaccagga aagaccacag ccgatttggc attctggaat ttatcagtat agcagtgggc      300

ctggtcagca ttcgaggcgt ggacagtgga ctctacctcg ggatgaatga gaagggggag      360

ctgtatggat cagaaaaact aacccaagag tgtgtattca gagaacagtt cgaagaaaac      420

tggtataata cgtactcgtc aaacctatat aagcacgtgg acactggaag gcgatactat      480

gttgcattaa ataaagatgg gaccccgaga gaagggacta ggactaaacg gcaccagaaa      540

ttcacacatt ttttacctag accagtggac cccgacaaag tacctgaact gtataaggat      600

attctaagcc aaagt                                                       615


<210>  3567
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  3567
aaaaaaaaag tgaagaatgg acttcacagc aaagtggtct cagaacaaaa ggacactctg       60

ggcaacaccc agattaagca gaaaagcagg cccgggaaca aaggcaagtt tgtcaccaaa      120

gaccaagcca actgcagatg ggctgctact gagcaggagg agggcatctc tctcaaggtt      180

gagtgcactc aattggacca tgaattttcc tgtgtctttg ctggcaatcc aacctcatgc      240

ctaaagctca aggatgagag agtctattgg aaacaagttg cccggaatct gcgctcacag      300

aaagacatct gtagatattc caagacagct gtgaaaacca gagtgtgcag aaaggatttt      360

ccagaatcca gtcttaagct agtcagctcc actctatttg ggaacacaaa gcccaggaag      420

gagaaaacag agatgtcccc cagggagcac atcaagggca aagagaccac cccctctagc      480

ctagcagtga cccagaccat ggccaccaaa gctcccgagt gtgtggagga cccagatatg      540

gcaaaccaga ggaagactgc cctggagttc tgtggagaga cttggagctc tctctgcaca      600

ttcttcctca gcatagtgca ggacacgtca tgc                                   633


<210>  3568
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  3568
cggagggaga aaggggcggc tagcaacgtg gcggagccgg tccccgggcc cactggcggc       60

tcctcgggtc gcttcctcag ccccgagcag cacgcgtgca gctggcagct cctgctgccc      120

gccccggagg ccgcagcggg cagcgagctg gcgctgcgct gccagagccc ggacggggcg      180

cgccaccagt gcgcctaccg cgggcatccg gagcgctgcg cagcctacgc cgctcgccgc      240

gcgcacttct ggaagcaggt gctgggaggg ctgcgcaaga agcggaggcc ctgtcacgac      300

cccgcgccgc tccaggcccg cttgtgcgcg ggcaagaagg gccacggcgc cgagctgcgg      360

ctagtgcccc gcgcgtcccc gcccgcacgc cccaccgtcg cgggattcgc gggggagtcc      420

aagccccggg cccggaaccg ggggcggacc cgggagcgtg cgtccggccc agccgctggg      480

accccgcctc cccaaagcgc accgcccaaa gaaaacccct cagagaggaa gaccaacgag      540

ggcaagagga aggcggcctt ggtccccaac gaggagcgac ccatggggac cgggcccgac      600

cccgacgggc tggacgggaa cgcggagctc acggagacct actgcgctga gaagtggcac      660

tccctctgca acttctttgt caatttctgg aacggc                                696


<210>  3569
<211>  1059
<212>  DNA
<213>  Homo Sapiens

<400>  3569
aggccgtccc cgaccttgcc tgaacaagcc cagccctggg gagcccctgt ggaagtggag       60

tccttcctgg tccaccccgg tgacctgctg cagcttcgct gtcggctgcg ggacgatgtg      120

cagagcatca actggctgcg ggacggggtg cagctggcgg aaagcaaccg cacccgcatc      180

acaggggagg aggtggaggt gcaggactcc gtgcccgcag actccggcct ctatgcttgc      240

gtaaccagca gcccctcggg cagtgacacc acctacttct ccgtcaatgt ttcagatgct      300

ctcccctcct cggaggatga tgatgatgat gatgactcct cttcagagga gaaagaaaca      360

gataacacca aaccaaaccc cgtagctcca tattggacat ccccagaaaa gatggaaaag      420

aaattgcatg cagtgccggc tgccaagaca gtgaagttca aatgcccttc cagtgggacc      480

ccaaacccca cactgcgctg gttgaaaaat ggcaaagaat tcaaacctga ccacagaatt      540

ggaggctaca aggtccgtta tgccaccggg agcatcataa tggactctgt ggtgccctct      600

gacaagggca actacacctg cattgtggag aatgagtacg gcagcatcaa ccacacatac      660

cagctggatg tcgtggagcg gtcccctcac cggcccatcc tgcaagcagg gttgcccgcc      720

aacaaaacag tggccctggg tagcaacgtg gagttcatgt gtaaggtgta cagtgacccg      780

cagccgcaca tccagtggct aaagcacatc gaggtgaatg ggagcaagat tggcccagac      840

aacctgcctt atgtccagat cttgaagact gctggagtta ataccaccga caaagagatg      900

gaggtgcttc acttaagaaa tgtctccttt gaggacgcag gggagtatac gtgcttggcg      960

ggtaactcta tcggactctc ccatcactct gcatggttga ccgttctgga agccctggaa     1020

gagaggccgg cagtgatgac ctcgcccctg tacctggag                            1059


<210>  3570
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  3570
cggccctcct tcagtttagt tgaggatacc acattagagc cagaaggagc accatactgg       60

accaacacag aaaagatgga aaagcggctc catgctgtgc ctgcggccaa cactgtcaag      120

tttcgctgcc cagccggggg gaacccaatg ccaaccatgc ggtggctgaa aaacgggaag      180

gagtttaagc aggagcatcg cattggaggc tacaaggtac gaaaccagca ctggagcctc      240

attatggaaa gtgtggtccc atctgacaag ggaaattata cctgtgtggt ggagaatgaa      300

tacgggtcca tcaatcacac gtaccacctg gatgttgtgg agcgatcgcc tcaccggccc      360

atcctccaag ccggactgcc ggcaaatgcc tccacagtgg tcggaggaga cgtagagttt      420

gtctgcaagg tttacagtga tgcccagccc cacatccagt ggatcaagca cgtggaaaag      480

aacggcagta aatacgggcc cgacgggctg ccctacctca aggttctcaa ggccgccggt      540

gttaacacca cggacaaaga gattgaggtt ctctatattc ggaatgtaac ttttgaggac      600

gctggggaat atacgtgctt ggcgggtaat tctattggga tatcctttca ctctgcatgg      660

ttgacagttc tgccagcgcc tggaagagaa aaggagatta cagcttcccc agactacctg      720

gag                                                                    723


<210>  3571
<211>  1059
<212>  DNA
<213>  Homo Sapiens

<400>  3571
gaatccttgg gcactgagca aagagtcgta ggacgtgccg ctgaagttcc aggccccgaa       60

ccgggccaac aggaacaact ggtattcggg tcaggagatg cagtggaact ttcttgccct      120

cctcccggcg gggggcctat gggaccgaca gtatgggtta aagacggcac tggccttgtg      180

ccgagcgaaa gggtcttggt cggtcctcaa aggttgcagg ttttgaatgc ttcacacgag      240

gatagtggcg catattcatg tagacagaga ctgactcaac gtgtactatg tcatttcagc      300

gttagagtga ccgacgcacc gagctctgga gatgacgagg atggggaaga tgaggctgaa      360

gacactggag tggatacagg cgctccctac tggacgcgtc cggagcgtat ggataagaag      420

ctattagctg tcccggcggc aaatactgtc agatttagat gtccagcggc gggtaatcct      480

accccgtcca tatcatggtt aaaaaatggg agggagttta gaggcgaaca tagaattgga      540

ggtataaaat tgaggcacca gcaatggagt ttggtaatgg aatctgtagt gcccagcgat      600

aggggtaact atacgtgtgt ggtggagaac aagttcggga gtattagaca gacatatacc      660

ttggatgtcc ttgagcgtag cccacatcgt cccatattac aagcggggct accagctaat      720

cagaccgcag tgctgggcag cgatgtggag tttcactgca aagtttatag tgatgcacaa      780

cctcacatcc agtggctaaa acacgtggaa gtgaacggta gcaaggtcgg ccccgacgga      840

acgccctatg tcacggtgct taagacggca ggagcaaaca ctacggataa ggagcttgag      900

gttctgtccc tacataatgt caccttcgag gacgctggag aatatacctg cctagcgggt      960

aactccatcg gattttcaca ccattctgca tggttggtgg tcttgccagc tgaggaagaa     1020

ctagttgaag ctgacgaagc tggcagcgtc tacgcaggc                            1059


<210>  3572
<211>  1044
<212>  DNA
<213>  Homo Sapiens

<400>  3572
ctggaggcct ctgaggaagt ggagcttgag ccctgcctgg ctcccagcct ggagcagcaa       60

gagcaggagc tgacagtagc ccttgggcag cctgtgcgtc tgtgctgtgg gcgggctgag      120

cgtggtggcc actggtacaa ggagggcagt cgcctggcac ctgctggccg tgtacggggc      180

tggaggggcc gcctagagat tgccagcttc ctacctgagg atgctggccg ctacctctgc      240

ctggcacgag gctccatgat cgtcctgcag aatctcacct tgattacagg tgactccttg      300

acctccagca acgatgatga ggaccccaag tcccataggg acccctcgaa taggcacagt      360

tacccccagc aagcacccta ctggacacac ccccagcgca tggagaagaa actgcatgca      420

gtacctgcgg ggaacaccgt caagttccgc tgtccagctg caggcaaccc cacgcccacc      480

atccgctggc ttaaggatgg acaggccttt catggggaga accgcattgg aggcattcgg      540

ctgcgccatc agcactggag tctcgtgatg gagagcgtgg tgccctcgga ccgcggcaca      600

tacacctgcc tggtagagaa cgctgtgggc agcatccgct ataactacct gctagatgtg      660

ctggagcggt ccccgcaccg gcccatcctg caggccgggc tcccggccaa caccacagcc      720

gtggtgggca gcgacgtgga gctgctgtgc aaggtgtaca gcgatgccca gccccacatc      780

cagtggctga agcacatcgt catcaacggc agcagcttcg gagccgacgg tttcccctat      840

gtgcaagtcc taaagactgc agacatcaat agctcagagg tggaggtcct gtacctgcgg      900

aacgtgtcag ccgaggacgc aggcgagtac acctgcctcg caggcaattc catcggcctc      960

tcctaccagt ctgcctggct cacggtgctg ccagaggagg accccacatg gaccgcagca     1020

gcgcccgagg ccaggtatac ggac                                            1044


<210>  3573
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  3573
gcccgaggcc ccccaaagat ggcggacaag gtggtcccac ggcaggtggc ccggctgggc       60

cgcactgtgc ggctgcagtg cccagtggag ggggacccgc cgccgctgac catgtggacc      120

aaggatggcc gcaccatcca cagcggctgg agccgcttcc gcgtgctgcc gcaggggctg      180

aaggtgaagc aggtggagcg ggaggatgcc ggcgtgtacg tgtgcaaggc caccaacggc      240

ttcggcagcc tgagcgtcaa ctacaccctc gtcgtgctgg atgacattag cccagggaag      300

gagagcctgg ggcccgacag ctcctctggg ggtcaagagg accccgccag ccagcagtgg      360

gcacgaccgc gcttcacaca gccctccaag atgaggcgcc gggtgatcgc acggcccgtg      420

ggtagctccg tgcggctcaa gtgcgtggcc agcgggcacc ctcggcccga catcacgtgg      480

atgaaggacg accaggcctt gacgcgccca gaggccgctg agcccaggaa gaagaagtgg      540

acactgagcc tgaagaacct gcggccggag gacagcggca aatacacctg ccgcgtgtcg      600

aaccgcgcgg gcgccatcaa cgccacctac aaggtggatg tgatccagcg gacccgttcc      660

aagcccgtgc tcacaggcac gcaccccgtg aacacgacgg tggacttcgg ggggaccacg      720

tccttccagt gcaaggtgcg cagcgacgtg aagccggtga tccagtggct gaagcgcgtg      780

gagtacggcg ccgagggccg ccacaactcc accatcgatg tgggcggcca gaagtttgtg      840

gtgctgccca cgggtgacgt gtggtcgcgg cccgacggct cctacctcaa taagctgctc      900

atcacccgtg cccgccagga cgatgcgggc atgtacatct gccttggcgc caacaccatg      960

ggctacagct tccgcagcgc cttcctcacc gtgctgccag acccaaaacc gccagggcca     1020

cctgtggcct cctcgtcctc ggccactagc ctgccgtggc cc                        1062


<210>  3574
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  3574
tttgcggcaa ctttctatga cattgaaaca ctaaaagtta tagatgaaga atggcaaaga       60

actcagtgca gccctagaga aacgtgcgtg gaggtggcca gtgagctggg gaagagtacc      120

aacacattct tcaagccccc ttgtgtgaac gtgttccgat gtggtggctg ttgcaatgaa      180

gagagcctta tctgtatgaa caccagcacc tcgtacattt ccaaacagct ctttgagata      240

tcagtgcctt tgacatcagt acctgaatta gtgcctgtta aagttgccaa tcatacaggt      300

tgtaagtgct tgccaacagc cccccgccat ccatactcaa ttatcagaag a               351


<210>  3575
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3575
accctccagg tgacacagga caagatcatc tgtctaccca atcatgagct ccaggagaac       60

ttatcagagg ccccgtgcca gcaattgctg cctcggggga tccctgagca gattggggcc      120

ctgcaggagg ttaaaggcct taagaacaat ttggacctgc agcaatacag ctttattaac      180

cagctgtgtt atgagacggc cctgcactgg tatgccaag                             219


<210>  3576
<211>  1512
<212>  DNA
<213>  Homo Sapiens

<400>  3576
atcgacagca ccacctgccc ctcggtgtgc cgctgcgaca acggcttcat ctactgcaac       60

gaccggggac tcacatccat ccccgcagat atccctgatg atgccaccac cctctacctg      120

cagaacaacc agatcaacaa cgccggcatc ccccaggacc tcaagaccaa ggtcaacgtg      180

caggtcatct acctatacga gaatgacctg gatgagttcc ccatcaacct gccccgctcc      240

ctccgggagc tgcacctgca ggacaacaat gtgcgcacca ttgccaggga ctcgctggcc      300

cgcatcccgc tgctggagaa gctgcacctg gatgacaact ccgtgtccac cgtcagcatt      360

gaggaggacg ccttcgccga cagcaaacag ctcaagctgc tcttcctgag ccggaaccac      420

ctgagcagca tcccctcggg gctgccgcac acgctggagg agctgcggct ggatgacaac      480

cgcatctcca ccatcccgct gcatgccttc aagggcctca acagcctgcg gcgcctggtg      540

ctggacggta acctgctggc caaccagcgt atcgccgacg acaccttcag ccgcctacag      600

aacctcacag agctctcgct ggtgcgcaat tcgctggccg cgccacccct caacctgccc      660

agcgcccacc tgcagaagct ctacctgcag gacaatgcca tcagccacat cccctacaac      720

acgctggcca agatgcgtga gctggagcgg ctggacctgt ccaacaacaa cctgaccacg      780

ctgccccgcg gcctgttcga cgacctgggg aacctggccc agctgctgct caggaacaac      840

ccttggtttt gtggctgcaa cctcatgtgg ctgcgggact gggtgaaggc acgggcggcc      900

gtggtcaacg tgcggggcct catgtgccag ggccctgaga aggtccgggg catggccatc      960

aaggacatta ccagcgagat ggacgagtgt tttgagacgg ggccgcaggg cggcgtggcc     1020

aatgcggctg ccaagaccac ggccagcaac cacgcctctg ccaccacgcc ccagggttcc     1080

ctgtttaccc tcaaggccaa aaggccaggg ctgcgcctcc ccgactccaa cattgactac     1140

cccatggcca cgggtgatgg cgccaagacc ctggccatcc acgtgaaggc cctgacggca     1200

gactccatcc gcatcacgtg gaaggccacg ctccccgcct cctctttccg gctcagttgg     1260

ctgcgcctgg gccacagccc agccgtgggc tccatcacgg agaccttggt gcagggggac     1320

aagacagagt acctgctgac agccctggag cccaagtcca cctacatcat ctgcatggtc     1380

accatggaga ccagcaatgc ctacgtagct gatgagacac ccgtgtgtgc caaggcagag     1440

acagccgaca gctatggccc taccaccaca ctcaaccagg agcagaacgc tggccccatg     1500

gcgagcctgc cc                                                         1512


<210>  3577
<211>  1518
<212>  DNA
<213>  Homo Sapiens

<400>  3577
tgccctagtg tgtgccgctg cgacaggaac tttgtctact gtaatgagcg aagcttgacc       60

tcagtgcctc ttgggatccc ggagggcgta accgtactct acctccacaa caaccaaatt      120

aataatgctg gatttcctgc agaactgcac aatgtacagt cggtgcacac ggtctacctg      180

tatggcaacc aactggacga attccccatg aaccttccca agaatgtcag agttctccat      240

ttgcaggaaa acaatattca gaccatttca cgggctgctc ttgcccagct cttgaagctt      300

gaagagctgc acctggatga caactccata tccacagtgg gggtggaaga cggggccttc      360

cgggaggcta ttagcctcaa attgttgttt ttgtctaaga atcacctgag cagtgtgcct      420

gttgggcttc ctgtggactt gcaagagctg agagtggatg aaaatcgaat tgctgtcata      480

tccgacatgg ccttccagaa tctcacgagc ttggagcgtc ttattgtgga cgggaacctc      540

ctgaccaaca agggtatcgc cgagggcacc ttcagccatc tcaccaagct caaggaattt      600

tcaattgtac gtaattcgct gtcccaccct cctcccgatc tcccaggtac gcatctgatc      660

aggctctatt tgcaggacaa ccagataaac cacattcctt tgacagcctt ctcaaatctg      720

cgtaagctgg aacggctgga tatatccaac aaccaactgc ggatgctgac tcaaggggtt      780

tttgataatc tctccaacct gaagcagctc actgctcgga ataacccttg gttttgtgac      840

tgcagtatta aatgggtcac agaatggctc aaatatatcc cttcatctct caacgtgcgg      900

ggtttcatgt gccaaggtcc tgaacaagtc cgggggatgg ccgtcaggga attaaatatg      960

aatcttttgt cctgtcccac cacgaccccc ggcctgcctc tcttcacccc agccccaagt     1020

acagcttctc cgaccactca gcctcccacc ctctctattc caaaccctag cagaagctac     1080

acgcctccaa ctcctaccac atcgaaactt cccacgattc ctgactggga tggcagagaa     1140

agagtgaccc cacctatttc tgaacggatc cagctctcta tccattttgt gaatgatact     1200

tccattcaag tcagctggct ctctctcttc accgtgatgg catacaaact cacatgggtg     1260

aaaatgggcc acagtttagt agggggcatc gttcaggagc gcatagtcag cggtgagaag     1320

caacacctga gcctggttaa cttagagccc cgatccacct atcggatttg tttagtgcca     1380

ctggatgctt ttaactaccg cgcggtagaa gacaccattt gttcagaggc caccacccat     1440

gcctcctatc tgaacaacgg cagcaacaca gcgtccagcc atgagcagac gacgtcccac     1500

agcatgggct cccccttt                                                   1518


<210>  3578
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  3578
aaatcctgtc catctgtgtg tcgctgcgat gcgggtttca tttactgtaa tgatcgcttt       60

ctgacatcca ttccaacagg aataccagag gatgctacaa ctctctacct tcagaacaac      120

caaataaata atgctgggat tccttcagat ttgaaaaact tgctgaaagt agaaagaata      180

tacctatacc acaacagttt agatgaattt cctaccaacc tcccaaagta tgtaaaagag      240

ttacatttgc aagaaaataa cataaggact atcacttatg attcactttc aaaaattccc      300

tatctggaag aattacattt agatgacaac tctgtctctg cagttagcat agaagaggga      360

gcattccgag acagcaacta tctccgactg cttttcctgt cccgtaatca ccttagcaca      420

attccctggg gtttgcccag gactatagaa gaactacgct tggatgataa tcgcatatcc      480

actatttcat caccatctct tcaaggtctc actagtctaa aacgcctggt tctagatgga      540

aacctgttga acaatcatgg tttaggtgac aaagttttct tcaacctagt taatttgaca      600

gagctgtccc tggtgcggaa ttccctgact gctgcaccag taaaccttcc aggcacaaac      660

ctgaggaagc tttatcttca agataaccac atcaatcggg tgcccccaaa tgctttttct      720

tatctaaggc agctctatcg actggatatg tccaataata acctaagtaa tttacctcag      780

ggtatctttg atgatttgga caatataaca caactgattc ttcgcaacaa tccctggtat      840

tgcgggtgca agatgaaatg ggtacgtgac tggttacaat cactacctgt gaaggtcaac      900

gtgcgtgggc tcatgtgcca agccccagaa aaggttcgtg ggatggctat taaggatctc      960

aatgcagaac tgtttgattg taaggacagt gggattgtaa gcaccattca gataaccact     1020

gcaataccca acacagtgta tcctgcccaa ggacagtggc cagctccagt gaccaaacag     1080

ccagatatta agaaccccaa gctcactaag gatcaccaaa ccacagggag tccctcaaga     1140

aaaacaatta caattactgt gaagtctgtc acctctgata ccattcatat ctcttggaaa     1200

cttgctctac ctatgactgc tttgagactc agctggctta aactgggcca tagcccggca     1260

tttggatcta taacagaaac aattgtaaca ggggaacgca gtgagtactt ggtcacagcc     1320

ctggagcctg attcacccta taaagtatgc atggttccca tggaaaccag caacctctac     1380

ctatttgatg aaactcctgt ttgtattgag actgaaactg caccccttcg aatgtacaac     1440

cctacaacca ccctcaatcg agagcaagag aaagaacctt acaaaaaccc caatttacct     1500


<210>  3579
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  3579
tcaaaattaa aagatcctga actgagttta aaaggcaccc agcacatcat gcaagcaggc       60

cagacactgc atctccaatg caggggggaa gcagcccata aatggtcttt gcctgaaatg      120

gtgagtaagg aaagcgaaag gctgagcata actaaatctg cctgtggaag aaatggcaaa      180

caattctgca gtactttaac cttgaacaca gctcaagcaa accacactgg cttctacagc      240

tgcaaatatc tagctgtacc tacttcaaag aagaaggaaa cagaatctgc aatctatata      300

tttattagtg atacaggtag acctttcgta gagatgtaca gtgaaatccc cgaaattata      360

cacatgactg aaggaaggga gctcgtcatt ccctgccggg ttacgtcacc taacatcact      420

gttactttaa aaaagtttcc acttgacact ttgatccctg atggaaaacg cataatctgg      480

gacagtagaa agggcttcat catatcaaat gcaacgtaca aagaaatagg gcttctgacc      540

tgtgaagcaa cagtcaatgg gcatttgtat aagacaaact atctcacaca tcgacaaacc      600

aatacaatca tagatgtcca aataagcaca ccacgcccag tcaaattact tagaggccat      660

actcttgtcc tcaattgtac tgctaccact cccttgaaca cgagagttca aatgacctgg      720

agttaccctg atgaaaaaaa taagagagct tccgtaaggc gacgaattga ccaaagcaat      780

tcccatgcca acatattcta cagtgttctt actattgaca aaatgcagaa caaagacaaa      840

ggactttata cttgtcgtgt aaggagtgga ccatcattca aatctgttaa cacctcagtg      900

catatatatg ataaagcatt catcactgtg aaacatcgaa aacagcaggt gcttgaaacc      960

gtagctggca agcggtctta ccggctctct atgaaagtga aggcatttcc ctcgccggaa     1020

gttgtatggt taaaagatgg gttacctgcg actgagaaat ctgctcgcta tttgactcgt     1080

ggctactcgt taattatcaa ggacgtaact gaagaggatg cagggaatta tacaatcttg     1140

ctgagcataa aacagtcaaa tgtgtttaaa aacctcactg ccactctaat tgtcaatgtg     1200

aaaccccaga tttacgaaaa ggccgtgtca tcgtttccag acccggctct ctacccactg     1260

ggcagcagac aaatcctgac ttgtaccgca tatggtatcc ctcaacctac aatcaagtgg     1320

ttctggcacc cctgtaacca taatcattcc gaagcaaggt gtgacttttg ttccaataat     1380

gaagagtcct ttatcctgga tgctgacagc aacatgggaa acagaattga gagcatcact     1440

cagcgcatgg caataataga aggaaagaat aagatggcta gcaccttggt tgtggctgac     1500

tctagaattt ctggaatcta catttgcata gcttccaata aagttgggac tgtgggaaga     1560

aacataagct tttatatcac agatgtgcca aatgggtttc atgttaactt ggaaaaaatg     1620

ccgacggaag gagaggacct gaaactgtct tgcacagtta acaagttctt atacagagac     1680

gttacttgga ttttactgcg gacagttaat aacagaacaa tgcactacag tattagcaag     1740

caaaaaatgg ccatcactaa ggagcactcc atcactctta atcttaccat catgaatgtt     1800

tccctgcaag attcaggcac ctatgcctgc agagccagga atgtatacac aggggaagaa     1860

atcctccaga agaaagaaat tacaatcaga ggtgagcact gcaacaaaaa ggctgttttc     1920

tctcggatct ccaaatttaa aagcacaagg aatgattgta ccacacaaag taatgtaaaa     1980

cat                                                                   1983


<210>  3580
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  3580
aatcaagatc tgcctgtgat caagtgtgtt ttaatcaatc ataagaacaa tgattcatca       60

gtggggaagt catcatcata tcccatggta tcagaatccc cggaagacct cgggtgtgcg      120

ttgagacccc agagctcagg gacagtgtac gaagctgccg ctgtggaagt ggatgtatct      180

gcttccatca cactgcaagt gctggtcgat gccccaggga acatttcctg tctctgggtc      240

tttaagcaca gctccctgaa ttgccagcca cattttgatt tacaaaacag aggagttgtt      300

tccatggtca ttttgaaaat gacagaaacc caagctggag aatacctact ttttattcag      360

agtgaagcta ccaattacac aatattgttt acagtgagta taagaaatac cctgctttac      420

acattaagaa gaccttactt tagaaaaatg gaaaaccagg acgccctggt ctgcatatct      480

gagagcgttc cagagccgat cgtggaatgg gtgctttgcg attcacaggg ggaaagctgt      540

aaagaagaaa gtccagctgt tgttaaaaag gaggaaaaag tgcttcatga attatttggg      600

atggacataa ggtgctgtgc cagaaatgaa ctgggcaggg aatgcaccag gctgttcaca      660

atagatctaa atcaaactcc tcagaccaca ttgccacaat tatttcttaa agtaggggaa      720

cccttatgga taaggtgcaa agctgttcat gtgaaccatg gattcgggct cacctgggaa      780

ttagaaaaca aagcactcga ggagggcaac tactttgaga tgagtaccta ttcaacaaac      840

agaactatga tacggattct gtttgctttt gtatcatcag tggcaagaaa cgacaccgga      900

tactacactt gttcctcttc aaagcatccc agtcaatcag ctttggttac catcgtagaa      960

aagggattta taaatgctac caattcaagt gaagattatg aaattgacca atatgaagag     1020

ttttgttttt ctgtcaggtt taaagcctac ccacaaatca gatgtacgtg gaccttctct     1080

cgaaaatcat ttccttgtga gcaaaagggt cttgataacg gatacagcat atccaagttt     1140

tgcaatcata agcaccagcc aggagaatat atattccatg cagaaaatga tgatgcccaa     1200

tttaccaaaa tgttcacgct gaatataaga aggaaacctc aagtgctcgc agaagcatcg     1260

gcaagtcagg cgtcctgttt ctcggatgga tacccattac catcttggac ctggaagaag     1320

tgttcagaca agtctcccaa ctgcacagaa gagatcacag aaggagtctg gaatagaaag     1380

gctaacagaa aagtgtttgg acagtgggtg tcgagcagta ctctaaacat gagtgaagcc     1440

ataaaagggt tcctggtcaa gtgctgtgca tacaattccc ttggcacatc ttgtgagacg     1500

atccttttaa actctccagg ccccttccct ttcatccaag acaacatctc a              1551


<210>  3581
<211>  1074
<212>  DNA
<213>  Homo Sapiens

<400>  3581
cagtatgaag atgaccctca ttggtggttc cactacctcc gcagccagca gtccacctac       60

tacgatccct atgaccctta cccgtatgag acctacgagc cttaccccta tggggtggat      120

gaagggccag cctacaccta cggctctcca tcccctccag atccccgcga ctgcccccag      180

gagtgcgact gcccacccaa cttccccacg gccatgtact gtgacaatcg caacctcaag      240

tacctgccct tcgttccctc ccgcatgaag tatgtgtact tccagaacaa ccagatcacc      300

tccatccagg aaggcgtctt tgacaatgcc acagggctgc tctggattgc tctccacggc      360

aaccagatca ccagtgataa ggtgggcagg aaggtcttct ccaagctgag gcacctggag      420

aggctgtacc tggaccacaa caacctgacc cggatgcccg gtcccctgcc tcgatccctg      480

agagagctcc atctcgacca caaccagatc tcacgggtcc ccaacaatgc tctggagggg      540

ctggagaacc tcacggcctt gtacctccaa cacaatgaga tccaggaagt gggcagttcc      600

atgaggggcc tccggtcact gatcttgctg gacctgagtt ataaccacct tcggaaggtg      660

cctgatgggc tgccctcagc tcttgagcag ctgtacatgg agcacaacaa tgtctacacc      720

gtccccgata gctacttccg gggggcgccc aagctgctgt atgtgcggct gtcccacaac      780

agtctaacca acaatggcct ggcctccaac accttcaatt ccagcagcct ccttgagcta      840

gacctctcct acaaccagct gcagaagatc cccccagtca acaccaacct ggagaacctc      900

tacctccaag gcaataggat caatgagttc tccatcagca gcttctgcac cgtggtggac      960

gtcgtgaact tctccaagct gcaggtgctg cgcctggacg ggaacgagat caagcgcagc     1020

gccatgcctg ccgacgcgcc cctctgcctg cgccttgcca gcctcatcga gatc           1074


<210>  3582
<211>  6435
<212>  DNA
<213>  Homo Sapiens

<400>  3582
caggctcagc aaatggttca gccccagtcc ccggtggctg tcagtcaaag caagcccggt       60

tgttatgaca atggaaaaca ctatcagata aatcaacagt gggagcggac ctacctaggc      120

aatgcgttgg tttgtacttg ttatggagga agccgaggtt ttaactgcga gagtaaacct      180

gaagctgaag agacttgctt tgacaagtac actgggaaca cttaccgagt gggtgacact      240

tatgagcgtc ctaaagactc catgatctgg gactgtacct gcatcggggc tgggcgaggg      300

agaataagct gtaccatcgc aaaccgctgc catgaagggg gtcagtccta caagattggt      360

gacacctgga ggagaccaca tgagactggt ggttacatgt tagagtgtgt gtgtcttggt      420

aatggaaaag gagaatggac ctgcaagccc atagctgaga agtgttttga tcatgctgct      480

gggacttcct atgtggtcgg agaaacgtgg gagaagccct accaaggctg gatgatggta      540

gattgtactt gcctgggaga aggcagcgga cgcatcactt gcacttctag aaatagatgc      600

aacgatcagg acacaaggac atcctataga attggagaca cctggagcaa gaaggataat      660

cgaggaaacc tgctccagtg catctgcaca ggcaacggcc gaggagagtg gaagtgtgag      720

aggcacacct ctgtgcagac cacatcgagc ggatctggcc ccttcaccga tgttcgtgca      780

gctgtttacc aaccgcagcc tcacccccag cctcctccct atggccactg tgtcacagac      840

agtggtgtgg tctactctgt ggggatgcag tggctgaaga cacaaggaaa taagcaaatg      900

ctttgcacgt gcctgggcaa cggagtcagc tgccaagaga cagctgtaac ccagacttac      960

ggtggcaact caaatggaga gccatgtgtc ttaccattca cctacaatgg caggacgttc     1020

tactcctgca ccacagaagg gcgacaggac ggacatcttt ggtgcagcac aacttcgaat     1080

tatgagcagg accagaaata ctctttctgc acagaccaca ctgttttggt tcagactcga     1140

ggaggaaatt ccaatggtgc cttgtgccac ttccccttcc tatacaacaa ccacaattac     1200

actgattgca cttctgaggg cagaagagac aacatgaagt ggtgtgggac cacacagaac     1260

tatgatgccg accagaagtt tgggttctgc cccatggctg cccacgagga aatctgcaca     1320

accaatgaag gggtcatgta ccgcattgga gatcagtggg ataagcagca tgacatgggt     1380

cacatgatga ggtgcacgtg tgttgggaat ggtcgtgggg aatggacatg cattgcctac     1440

tcgcagcttc gagatcagtg cattgttgat gacatcactt acaatgtgaa cgacacattc     1500

cacaagcgtc atgaagaggg gcacatgctg aactgtacat gcttcggtca gggtcggggc     1560

aggtggaagt gtgatcccgt cgaccaatgc caggattcag agactgggac gttttatcaa     1620

attggagatt catgggagaa gtatgtgcat ggtgtcagat accagtgcta ctgctatggc     1680

cgtggcattg gggagtggca ttgccaacct ttacagacct atccaagctc aagtggtcct     1740

gtcgaagtat ttatcactga gactccgagt cagcccaact cccaccccat ccagtggaat     1800

gcaccacagc catctcacat ttccaagtac attctcaggt ggagacctaa aaattctgta     1860

ggccgttgga aggaagctac cataccaggc cacttaaact cctacaccat caaaggcctg     1920

aagcctggtg tggtatacga gggccagctc atcagcatcc agcagtacgg ccaccaagaa     1980

gtgactcgct ttgacttcac caccaccagc accagcacac ctgtgaccag caacaccgtg     2040

acaggagaga cgactccctt ttctcctctt gtggccactt ctgaatctgt gaccgaaatc     2100

acagccagta gctttgtggt ctcctgggtc tcagcttccg acaccgtgtc gggattccgg     2160

gtggaatatg agctgagtga ggagggagat gagccacagt acctggatct tccaagcaca     2220

gccacttctg tgaacatccc tgacctgctt cctggccgaa aatacattgt aaatgtctat     2280

cagatatctg aggatgggga gcagagtttg atcctgtcta cttcacaaac aacagcgcct     2340

gatgcccctc ctgacccgac tgtggaccaa gttgatgaca cctcaattgt tgttcgctgg     2400

agcagacccc aggctcccat cacagggtac agaatagtct attcgccatc agtagaaggt     2460

agcagcacag aactcaacct tcctgaaact gcaaactccg tcaccctcag tgacttgcaa     2520

cctggtgttc agtataacat cactatctat gctgtggaag aaaatcaaga aagtacacct     2580

gttgtcattc aacaagaaac cactggcacc ccacgctcag atacagtgcc ctctcccagg     2640

gacctgcagt ttgtggaagt gacagacgtg aaggtcacca tcatgtggac accgcctgag     2700

agtgcagtga ccggctaccg tgtggatgtg atccccgtca acctgcctgg cgagcacggg     2760

cagaggctgc ccatcagcag gaacaccttt gcagaagtca ccgggctgtc ccctggggtc     2820

acctattact tcaaagtctt tgcagtgagc catgggaggg agagcaagcc tctgactgct     2880

caacagacaa ccaaactgga tgctcccact aacctccagt ttgtcaatga aactgattct     2940

actgtcctgg tgagatggac tccacctcgg gcccagataa caggataccg actgaccgtg     3000

ggccttaccc gaagaggcca gcccaggcag tacaatgtgg gtccctctgt ctccaagtac     3060

cccctgagga atctgcagcc tgcatctgag tacaccgtat ccctcgtggc cataaagggc     3120

aaccaagaga gccccaaagc cactggagtc tttaccacac tgcagcctgg gagctctatt     3180

ccaccttaca acaccgaggt gactgagacc accattgtga tcacatggac gcctgctcca     3240

agaattggtt ttaagctggg tgtacgacca agccagggag gagaggcacc acgagaagtg     3300

acttcagact caggaagcat cgttgtgtcc ggcttgactc caggagtaga atacgtctac     3360

accatccaag tcctgagaga tggacaggaa agagatgcgc caattgtaaa caaagtggtg     3420

acaccattgt ctccaccaac aaacttgcat ctggaggcaa accctgacac tggagtgctc     3480

acagtctcct gggagaggag caccacccca gacattactg gttatagaat taccacaacc     3540

cctacaaacg gccagcaggg aaattctttg gaagaagtgg tccatgctga tcagagctcc     3600

tgcacttttg ataacctgag tcccggcctg gagtacaatg tcagtgttta cactgtcaag     3660

gatgacaagg aaagtgtccc tatctctgat accatcatcc cagctgttcc tcctcccact     3720

gacctgcgat tcaccaacat tggtccagac accatgcgtg tcacctgggc tccaccccca     3780

tccattgatt taaccaactt cctggtgcgt tactcacctg tgaaaaatga ggaagatgtt     3840

gcagagttgt caatttctcc ttcagacaat gcagtggtct taacaaatct cctgcctggt     3900

acagaatatg tagtgagtgt ctccagtgtc tacgaacaac atgagagcac acctcttaga     3960

ggaagacaga aaacaggtct tgattcccca actggcattg acttttctga tattactgcc     4020

aactctttta ctgtgcactg gattgctcct cgagccacca tcactggcta caggatccgc     4080

catcatcccg agcacttcag tgggagacct cgagaagatc gggtgcccca ctctcggaat     4140

tccatcaccc tcaccaacct cactccaggc acagagtatg tggtcagcat cgttgctctt     4200

aatggcagag aggaaagtcc cttattgatt ggccaacaat caacagtttc tgatgttccg     4260

agggacctgg aagttgttgc tgcgaccccc accagcctac tgatcagctg ggatgctcct     4320

gctgtcacag tgagatatta caggatcact tacggagaaa caggaggaaa tagccctgtc     4380

caggagttca ctgtgcctgg gagcaagtct acagctacca tcagcggcct taaacctgga     4440

gttgattata ccatcactgt gtatgctgtc actggccgtg gagacagccc cgcaagcagc     4500

aagccaattt ccattaatta ccgaacagaa attgacaaac catcccagat gcaagtgacc     4560

gatgttcagg acaacagcat tagtgtcaag tggctgcctt caagttcccc tgttactggt     4620

tacagagtaa ccaccactcc caaaaatgga ccaggaccaa caaaaactaa aactgcaggt     4680

ccagatcaaa cagaaatgac tattgaaggc ttgcagccca cagtggagta tgtggttagt     4740

gtctatgctc agaatccaag cggagagagt cagcctctgg ttcagactgc agtaaccact     4800

attcctgcac caactgacct gaagttcact caggtcacac ccacaagcct gagcgcccag     4860

tggacaccac ccaatgttca gctcactgga tatcgagtgc gggtgacccc caaggagaag     4920

accggaccaa tgaaagaaat caaccttgct cctgacagct catccgtggt tgtatcagga     4980

cttatggtgg ccaccaaata tgaagtgagt gtctatgctc ttaaggacac tttgacaagc     5040

agaccagctc agggtgttgt caccactctg gagaatgtca gcccaccaag aagggctcgt     5100

gtgacagatg ctactgagac caccatcacc attagctgga gaaccaagac tgagacgatc     5160

actggcttcc aagttgatgc cgttccagcc aatggccaga ctccaatcca gagaaccatc     5220

aagccagatg tcagaagcta caccatcaca ggtttacaac caggcactga ctacaagatc     5280

tacctgtaca ccttgaatga caatgctcgg agctcccctg tggtcatcga cgcctccact     5340

gccattgatg caccatccaa cctgcgtttc ctggccacca cacccaattc cttgctggta     5400

tcatggcagc cgccacgtgc caggattacc ggctacatca tcaagtatga gaagcctggg     5460

tctcctccca gagaagtggt ccctcggccc cgccctggtg tcacagaggc tactattact     5520

ggcctggaac cgggaaccga atatacaatt tatgtcattg ccctgaagaa taatcagaag     5580

agcgagcccc tgattggaag gaaaaagaca ggacaagaag ctctctctca gacaaccatc     5640

tcatgggccc cattccagga cacttctgag tacatcattt catgtcatcc tgttggcact     5700

gatgaagaac ccttacagtt cagggttcct ggaacttcta ccagtgccac tctgacaggc     5760

ctcaccagag gtgccaccta caacatcata gtggaggcac tgaaagacca gcagaggcat     5820

aaggttcggg aagaggttgt taccgtgggc aactctgtca acgaaggctt gaaccaacct     5880

acggatgact cgtgctttga cccctacaca gtttcccatt atgccgttgg agatgagtgg     5940

gaacgaatgt ctgaatcagg ctttaaactg ttgtgccagt gcttaggctt tggaagtggt     6000

catttcagat gtgattcatc tagatggtgc catgacaatg gtgtgaacta caagattgga     6060

gagaagtggg accgtcaggg agaaaatggc cagatgatga gctgcacatg tcttgggaac     6120

ggaaaaggag aattcaagtg tgaccctcat gaggcaacgt gttatgatga tgggaagaca     6180

taccacgtag gagaacagtg gcagaaggaa tatctcggtg ccatttgctc ctgcacatgc     6240

tttggaggcc agcggggctg gcgctgtgac aactgccgca gacctggggg tgaacccagt     6300

cccgaaggca ctactggcca gtcctacaac cagtattctc agagatacca tcagagaaca     6360

aacactaatg ttaattgccc aattgagtgc ttcatgcctt tagatgtaca ggctgacaga     6420

gaagattccc gagag                                                      6435


<210>  3583
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  3583
gaccggcctc cctctcctgt gaatgtgacg gtcactcacc tcagagccaa ctcggccact       60

gtgtcctggg acgtcccaga aggcaacatc gtcattggct actccatttc ccagcaacgg      120

cagaatggcc ccgggcagcg tgtgattcgg gaggtgaaca ccaccacccg ggcctgtgcc      180

ctctggggcc tggctgaaga cagtgactac acagtgcagg tcaggagcat cggccttcgg      240

ggagagagtc ccccagggcc ccgggtgcac ttccgaactc tcaagggttc tgaccggcta      300

ccttcaaaca gttcaagccc aggtgacatc acagtggaag gtctggatgg agagcggcca      360

ctgcagact                                                              369


<210>  3584
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  3584
gccccagtga acgtcaccgt caggcacctc aaggccaact ctgcagtggt gagctgggat       60

gttctggagg atgaggttgt catcggattt gccatctccc agcagaagaa ggatgtgcgg      120

atgctgcgct tcatccagga ggtgaacacc accacccgct catgtgccct ctgggacctg      180

gaggaggata cggagtacat agtccacgtg caggccatct ccattcaggg ccagagccca      240

gccagcgagc ctgtgctctt caagaccccg cgtgaggctg agaagatggc ctccaagaac      300

aaagatgagg taaccatgaa agagatgggg aggaaccaac agctgcggac a               351


<210>  3585
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  3585
gcacccggaa gagtgacgat ccaagaagat ccccctggcc acctgtctgt ggcttggtcc       60

agtgtagatc tgggtgacta ctatgtggtc tttgtgaaga gtgatgatgg cttggaagta      120

cactgcaaca catctctcac tcagtgcaac ttcttatctg agtgtggctt cacttatttt      180

attagtgttt ttgtctataa caaggcaggg caaagtcctt tgggtgacat attcaattat      240

accacagctc cctgttgtcc tagtgacatt aaccccgtgt tggtgtccag tgacagagtt      300

gagattgtct ggtctcctgt ccgtggtgcc gaactgtatg aaaccaaggc tgtagatggg      360

tacaacatgg ttgagtgcaa tgacactact cctgcgtgca ccctttcggc tctagagtgt      420

gacaccaagt acaacatcac agtgtattca ttcaatgaag tccgaggcag caatatgtca      480

tgtactcccc agttcataac cacagctcct tgcagtcctg aaataaaaaa tgtttcaagg      540

gatgcattct ccatgattaa tgtgcactgg cgatccacta atgatgatgc tacttacacg      600

gtgactgccc aaggggagaa aggactgtat cagtgcagca gcacaggaga gtcctgcacc      660

atgcggggct tgccctgtgg ctcagtgttc tctgtcactg ctgtggccga aacacaggca      720

ggacggagcc tgcccagcta cagtgtgccc ctggaaacag tgccatgctg tccaaccggt      780

ctgacagtaa ctcaaatcac ccagtcagta atcaacgtga gctggactat tgggagagtg      840

gctcaaaccc atgttgcagt tctggagtca cacactggac agtctaagtg tcacactcat      900

caaaaccact gcctcctagg gtgcatcaca tgtggcatca attacacagt gacattaaaa      960

gcaattagtg ccaccgggtt gactgcagat tgctcctacc aaagttattt ctctggtgcc     1020

tgctgccctt tgggggtgaa attatatagg ctgggcccta atggcatccg gatctactgg     1080

caagcctcca ggggctctgc caattacagc actgacctct atggctccaa aggcattttc     1140

acgtgcaccc cgagtgctgg cctcagtttc tgtgatgtca ctgagatacc ctgtggggat     1200

gtatacactg tgatggtctc accagttgct aaaacaggat tgaagcttac tttctgtcca     1260

aaaaaaatat attcagtaac ttgctctgga agtacacttg gaatggtgat ttatagaggg     1320

aagagaaatg aagaa                                                      1335


<210>  3586
<211>  2145
<212>  DNA
<213>  Homo Sapiens

<400>  3586
atggtgacac aagaatccat gctgaaggct gccttgcctc tctttaccag attcatcatc       60

agcaatggac tgcggaccga gcacggggtg tttgagatca cactggagac tgtggacaga      120

gccctgcctg tggtaaccag gaacaagggg ttgagactgg cccaaggggc cgtgggcctg      180

ctttcccctg acctccttca gctgaccgac cctgatacac ctgcggagaa cctcaccttc      240

ctcttggttc agctccccca gcatggccag ctctacctgt gggggacagg gctacttcaa      300

cacaatttca cccagcagga tgtggacagc aagaatgtgg cctatcggca ctcaggaggg      360

gactcccaga ctgactgctt tactttcatg gccacagacg ggacaaacca aggctttatt      420

gtgaatggga gagtgtggga agaacctgtt ttattcacca ttcaggtaga ccaattggac      480

aaaacagctc ctcgtatcac actcttgcat tccccttctc aagtggggct cctgaaaaat      540

ggctgctacg ggatttacat cacttcccgc gtgttgaagg catcagaccc tgacactgag      600

gacgatcaga tcatctttaa aattctacaa ggcccaaaac atggacatct ggagaacaca      660

acaacaggtg aatttatcca tgagaaattt agccaaaagg acttaaacag taagactatt      720

ctttacatca taaacccatc tttggaagta aattcagata ccgtggaatt tcaaatcatg      780

gaccccacag ggaactcggc cactcctcaa aatttggaac tgaagtggtc tcatattgaa      840

tggtcacaga ccgaatatga agtctgtgag aatgtgggtt tgttgccctt ggaaattatc      900

agaaggggat attccatgga ctcggccttt gtgggtataa aggtcaacca agtgtcagct      960

gcagttggaa aagatttcac cgtgattcca tctaaactga ttcagtttga cccaggaatg     1020

tcaactaaga tgtggaatat agcaattacc tatgacggat tagaggaaga tgatgaggtc     1080

tttgaagtaa ttctgaactc ccctgtgaat gcagttcttg gcacaaagac aaaagctgca     1140

gtgaaaattt tggactcaaa aggaggacaa tgccatcctt catattcctc caaccaaagc     1200

aagcacagca catgggagaa gggcatttgg catctgctgc ccccagggtc ttcctcatcc     1260

accacttctg gttcctttca tctggaaaga agacctcttc catcctccat gcagctagca     1320

gtcatcaggg gagacaccct gcggggcttt gattctacag atctttctca aaggaagctt     1380

aggacccgtg ggaatggcaa aacagttcgt ccatcctctg tttatagaaa tggaacagac     1440

atcatctata attatcatgg gatagtttcc ttgaaactgg aggatgacag tttcccaact     1500

cacaaaagga aggccaaagt atccatcatt agtcagccac aaaagacaat caaagtggca     1560

gaactgcctc aagcagataa ggtggaatcc acaactgact cacacttccc cagacaggac     1620

cagttgccct catttccaaa gaactgcact ctggaattaa agggactctt ccattttgaa     1680

gaaggcatcc agaagctgta tcagtgcaat gggatcgcct ggaaagcctg gagtccccaa     1740

accaaggatg tggaagacaa atcctgtcca gccgggtggc accagcactc aggctactgt     1800

cacatcttga tcacagagca gaaaggcacc tggaatgcgg ctgcccaagc ttgcagggaa     1860

caatacctgg gcaaccttgt aactgtattc tccaggcagc acatgcggtg gctctgggac     1920

attggtggga gaaagtcctt ttggataggt ttgaacgacc aagtgcatgc tggccactgg     1980

gagtggatcg gtggtgaacc tgttgccttc accaatggga gaagagggcc ctctccacgc     2040

tccaagcttg gaaagagctg tgttttggtt caaagacaag ggaaatggca aacaaaagac     2100

tgtaggagag ccaaacctca taattatggg tgttccagaa aactc                     2145


<210>  3587
<211>  1047
<212>  DNA
<213>  Homo Sapiens

<400>  3587
tgtcatcatc ggatctgtca ctgctctaac agggtttttc tctgccaaga gagcaaggtg       60

acagagattc cttctgacct cccgaggaat gccattgaac tgaggtttgt cctcaccaag      120

cttcgagtca tccaaaaagg tgcattttca ggatttgggg acctggagaa aatagagatc      180

tctcagaatg atgtcttgga ggtgatagag gcagatgtgt tctccaacct tcccaaatta      240

catgaaatta gaattgaaaa ggccaacaac ctgctctaca tcaaccctga ggccttccag      300

aaccttccca accttcaata tctgttaata tccaacacag gtattaagca ccttccagat      360

gttcacaaga ttcattctct ccaaaaagtt ttacttgaca ttcaagataa cataaacatc      420

cacacaattg aaagaaattc tttcgtgggg ctgagctttg aaagtgtgat tctatggctg      480

aataagaatg ggattcaaga aatacacaac tgtgcattca atggaaccca actagatgag      540

ctgaatctaa gcgataataa taatttagaa gaattgccta atgatgtttt ccacggagcc      600

tctggaccag tcattctaga tatttcaaga acaaggatcc attccctgcc tagctatggc      660

ttagaaaatc ttaagaagct gagggccagg tcgacttaca acttaaaaaa gctgcctact      720

ctggaaaagc ttgtcgccct catggaagcc agcctcacct atcccagcca ttgctgtgcc      780

tttgcaaact ggagacggca aatctctgag cttcatccaa tttgcaacaa atctatttta      840

aggcaagaag ttgattatat gactcagact aggggtcaga gatcctctct ggcagaagac      900

aatgagtcca gctacagcag aggatttgac atgacgtaca ctgagtttga ctatgactta      960

tgcaatgaag tggttgacgt gacctgctcc cctaagccag atgcattcaa cccatgtgaa     1020

gatatcatgg ggtacaacat cctcaga                                         1047


<210>  3588
<211>  1749
<212>  DNA
<213>  Homo Sapiens

<400>  3588
tggatggacc caggaaccag cagaggcccg gatgtgggtg tgggggagtc acaggcagag       60

gagcccagaa gctttgaagt cacaagaaga gaagggcttt ccagccacaa cgagctgctg      120

gcctcctgcg ggaagaagtt ctgcagccga gggagccggt gcgtgctcag caggaagaca      180

ggggagcccg aatgccagtg cctggaggca tgcaggccca gctacgtgcc tgtgtgcggc      240

tctgatggga ggttttatga aaaccactgt aagctccacc gtgctgcttg cctcctggga      300

aagaggatca ccgtcatcca cagcaaggac tgtttcctca aaggtgacac gtgcaccatg      360

gccggctacg cccgcttgaa gaatgtcctt ctggcactcc agacccgtct gcagccactc      420

caagaaggag acagcagaca agaccctgcc tcccagaagc gcctcctggt ggaatctctg      480

ttcagggact tagatgcaga tggcaatggc cacctcagca gctccgaact ggctcagcat      540

gtgctgaaga agcaggacct ggatgaagac ttacttggtt gctcaccagg tgacctcctc      600

cgatttgacg attacaacag tgacagctcc ctgaccctcc gcgagttcta cattgccttc      660

caagtggttc agctcagcct cgcccccgag gacagggtca gtgtgaccac agtgaccgtg      720

gggctgagca cagtgctgac ctgcgccgtc catggagacc tgaggccacc aatcatctgg      780

aagcgcaacg ggctcaccct gaacttcctg gacttggaag acatcaatga ctttggagag      840

gatgattccc tgtacatcac caaggtgacc accatccaca tgggcaatta cacctgccat      900

gcttccggcc acgagcagct gttccagacc cacgtcctgc aggtgaatgt gccgccagtc      960

atccgtgtct atccagagag ccaggcacag gagcctggag tggcagccag cctaagatgc     1020

catgctgagg gcattcccat gcccagaatc acttggctga aaaacggcgt ggatgtctca     1080

actcagatgt ccaaacagct ctccctttta gccaatggga gcgaactcca catcagcagt     1140

gttcggtatg aagacacagg ggcatacacc tgcattgcca aaaatgaagt gggtgtggat     1200

gaagatatct cctcgctctt cattgaagac tcagctagaa agacccttgc aaacatcctg     1260

tggcgagagg aaggcctcag cgtgggaaac atgttctatg tcttctccga cgacggtatc     1320

atcgtcatcc atcctgtgga ctgtgagatc cagaggcacc tcaaacccac ggaaaagatt     1380

ttcatgagct atgaagaaat ctgtcctcaa agagaaaaaa atgcaaccca gccctgccag     1440

tgggtatctg cagtcaatgt ccggaaccgg tacatctatg tggcccagcc agcactgagc     1500

agagtccttg tggtcgacat ccaagcccag aaagtcctac agtccatagg tgtggaccct     1560

ctgccggcta agctgtccta tgacaagtca catgaccaag tgtgggtcct gagctggggg     1620

gacgtgcaca agtcccgacc aagtctccag gtgatcacag aagccagcac cggccagagc     1680

cagcacctca tccgcacacc ctttgcagga gtggatgatt tcttcattcc cccaataaac     1740

cttgaacag                                                             1749


<210>  3589
<211>  2481
<212>  DNA
<213>  Homo Sapiens

<400>  3589
aggccaacca aagaaggagg atatggcctt aaatcctatc agcctctaat gagattgcga       60

cataagcagg aaaaaaatca agaaagttca agagtcaaag gatttatgat tcaggatggc      120

ccttttggat cttgtgaaaa taagtactgt ggtttgggaa gacactgtgt taccagcaga      180

gagacagggc aagcagaatg tgcctgtatg gacctttgca aacgtcacta caaacctgtg      240

tgtggatctg acggagaatt ctatgaaaac cactgtgaag tgcacagagc tgcttgcctg      300

aaaaaacaaa agattaccat tgttcacaat gaagactgct tctttaaagg agataagtgc      360

aagactactg aatacagcaa gatgaaaaat atgctattag atttacaaaa tcaaaaatat      420

attatgcaag aaaatgaaaa tcctaatggc gacgacatat ctcggaagaa gctattggtg      480

gatcaaatgt ttaaatattt tgatgcagac agtaatggac ttgtagatat taatgaacta      540

actcaggtga taaaacagga agaacttggc aaggatctct ttgattgtac tttgtatgtt      600

ctattgaaat atgatgattt taatgctgac aagcacctgg ctcttgaaga attttataga      660

gcattccaag tgatccagtt gagtctgcca gaagatcaga aactaagcat cactgcagca      720

actgtgggac aaagtgctgt tctgagctgt gccattcaag gaaccctgag acctcccatt      780

atctggaaaa ggaacaatat tattctaaat aatttagatt tggaagacat caatgacttt      840

ggagatgatg ggtccttgta tattactaag gttaccacaa ctcacgttgg caattacacc      900

tgctatgcag atggctatga acaagtctat cagactcaca tcttccaagt gaatgttcct      960

ccagtcatcc gggtgtatcc agagagtcag gctagagagc ctggggtaac tgccagtctt     1020

aggtgccatg cagagggcat accaaagcct cagcttggct ggttgaagaa tggaattgat     1080

attacaccaa agctttccaa acaactcacg cttcaagcaa atggcagtga ggttcacata     1140

agcaatgtgc gctatgaaga tactggagca tacacttgta tcgcaaagaa tgaagcagga     1200

gtggatgaag acatctcttc tctttttgtg gaagactctg ctagaaagac cctagctaac     1260

atattatgga gagaagaagg tctgggaatt gggaacatgt tctatgtttt ttatgaagat     1320

ggaatcaaag tgatacaacc catagaatgt gaatttcaga ggcacattaa gcctagtgaa     1380

aagctccttg gatttcagga tgaagtctgt cccaaagctg agggagatga agttcagagg     1440

tgtgtgtggg catcagctgt taatgtcaaa gacaagttca tttatgttgc acagccaact     1500

ttggacagag tccttattgt tgatgtgcag tcccaaaaag ttgttcaggc agtgagcaca     1560

gaccctgtcc cagttaaatt acactatgac aaatcacatg atcaggtctg ggtgctaagc     1620

tggggtacct tggagaagtc atcaccaaca ctacaggtaa ttaccctggc cagtgggaat     1680

gtgcctcacc acacgatcca cacccaacca gtgggaaagc aatttgacag agtggatgat     1740

tttttcattc ccaccacaac actcattatc acccatatga ggtttggatt tattcttcat     1800

aaagatgaag ctgcactaca aaaaattgat attgaaacca tgtcatacat caagacaatt     1860

aacttgaagg actataagtg cgttcctcag tcattggcat atacacactt gggaggctac     1920

tacttcattg gctgcaaacc tgacagcacc ggagcagttt ccccacaggt catggtggac     1980

ggtgtaactg actcagtcat tgggttcaat agtgatgtga cgggcactcc atatgtctct     2040

ccagatggcc actaccttgt cagcattaat gatgtgaaag gtcttgtaag ggttcagtac     2100

attaccatca gaggagaaat acaggaggct tttgatattt acacaaatct gcacatatct     2160

gatctggcat ttcaaccatc ctttactgaa gcccaccaat ataacatcta cggtagttca     2220

agcacacaaa ctgatgtgct ctttgtggag ctctcttctg ggaaggtcaa gatgataaag     2280

agtctcaagg aaccactcaa ggcagaagaa tggccttgga accggaaaaa caggcaaatc     2340

caggacagtg gcttgtttgg tcaatacctg atgacacctt ccaaggactc tctcttcatc     2400

ctagatggac gactcaataa attaaactgt gagatcactg aagttgaaaa aggaaataca     2460

gtcatttggg ttggagatgc c                                               2481


<210>  3590
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  3590
ggctgggacc tgacggtgaa gatgctggcg ggcaacgaat tccaggtgtc cctgagcagc       60

tccatgtcgg tgtcagagct gaaggcgcag atcacccaga agatcggcgt gcacgccttc      120

cagcagcgtc tggctgtcca cccgagcggt gtggcgctgc aggacagggt cccccttgcc      180

agccagggcc tgggccccgg cagcacggtc ctgctggtgg tggacaaatg cgacgaacct      240

ctgagcatcc tggtgaggaa taacaagggc cgcagcagca cctacgaggt acggctgacg      300

cagaccgtgg cccacctgaa gcagcaagtg agcgggctgg agggtgtgca ggacgacctg      360

ttctggctga ccttcgaggg gaagcccctg gaggaccagc tcccgctggg ggagtacggc      420

ctcaagcccc tgagcaccgt gttcatgaat ctgcgcctgc ggggaggc                   468


<210>  3591
<211>  1944
<212>  DNA
<213>  Homo Sapiens

<400>  3591
gcgctgttgc cggcgcgcga ggccacgcag ttcctgcggc ccaggcagcg ccgcgccttt       60

caggtcttcg aggaggccaa gcagggccac ctggagaggg agtgcgtgga ggagctgtgc      120

agccgcgagg aggcgcggga ggtgttcgag aacgaccccg agacggatta tttttaccca      180

agatacttag actgcatcaa caagtatggg tctccgtaca ccaaaaactc aggcttcgcc      240

acctgcgtgc aaaacctgcc tgaccagtgc acgcccaacc cctgcgatag gaaggggacc      300

caagcctgcc aggacctcat gggcaacttc ttctgcctgt gtaaagctgg ctgggggggc      360

cggctctgcg acaaagatgt caacgaatgc agccaggaga acgggggctg cctccagatc      420

tgccacaaca agccgggtag cttccactgt tcctgccaca gcggcttcga gctctcctct      480

gatggcagga cctgccaaga catagacgag tgcgcagact cggaggcctg cggggaggcg      540

cgctgcaaga acctgcccgg ctcctactcc tgcctctgtg acgagggctt tgcgtacagc      600

tcccaggaga aggcttgccg agatgtggac gagtgtctgc agggccgctg tgagcaggtc      660

tgcgtgaact ccccagggag ctacacctgc cactgtgacg ggcgtggggg cctcaagctg      720

tcccaggaca tggacacctg tgaggacatc ttgccgtgcg tgcccttcag cgtggccaag      780

agtgtgaagt ccttgtacct gggccggatg ttcagtggga cccccgtgat ccgactgcgc      840

ttcaagaggc tgcagcccac caggctggta gctgagtttg acttccggac ctttgacccc      900

gagggcatcc tcctctttgc cggaggccac caggacagca cctggatcgt gctggccctg      960

agagccggcc ggctggagct gcagctgcgc tacaacggtg tcggccgtgt caccagcagc     1020

ggcccggtca tcaaccatgg catgtggcag acaatctctg ttgaggagct ggcgcggaat     1080

ctggtcatca aggtcaacag ggatgctgtc atgaaaatcg cggtggccgg ggacttgttc     1140

caaccggagc gaggactgta tcatctgaac ctgaccgtgg gaggtattcc cttccatgag     1200

aaggacctcg tgcagcctat aaaccctcgt ctggatggct gcatgaggag ctggaactgg     1260

ctgaacggag aagacaccac catccaggaa acggtgaaag tgaacacgag gatgcagtgc     1320

ttctcggtga cggagagagg ctctttctac cccgggagcg gcttcgcctt ctacagcctg     1380

gactacatgc ggacccctct ggacgtcggg actgaatcaa cctgggaagt agaagtcgtg     1440

gctcacatcc gcccagccgc agacacaggc gtgctgtttg cgctctgggc ccccgacctc     1500

cgtgccgtgc ctctctctgt ggcactggta gactatcact ccacgaagaa actcaagaag     1560

cagctggtgg tcctggccgt ggagcatacg gccttggccc taatggagat caaggtctgc     1620

gacggccaag agcacgtggt caccgtctcg ctgagggacg gtgaggccac cctggaggtg     1680

gacggcacca ggggccagag cgaggtgagc gccgcgcagc tgcaggagag gctggccgtg     1740

ctcgagaggc acctgcggag ccccgtgctc acctttgctg gcggcctgcc agatgtgccg     1800

gtgacttcag cgccagtcac cgcgttctac cgcggctgca tgacactgga ggtcaaccgg     1860

aggctgctgg acctggacga ggcggcgtac aagcacagcg acatcacggc ccactcctgc     1920

ccccccgtgg agcccgccgc agcc                                            1944


<210>  3592
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  3592
cagtgggatg agccgagggt gtgctcccgg aggtacctga aggtggactt cgcagacatc       60

ggctggaatg aatggataat ctcaccgaaa tcttttgatg cctactactg cgcgggagca      120

tgtgagttcc ccatgcctaa gatcgttcgt ccatccaacc atgccaccat ccagagcatt      180

gtcagggctg tgggcatcat ccctggcatc ccagagccct gctgtgttcc cgataagatg      240

aactcccttg gggtcctctt cctggatgag aatcggaatg tggttctgaa ggtgtacccc      300

aacatgtccg tggacacctg tgcctgccgg                                       330


<210>  3593
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  3593
aacctgggtc tggactgcga cgagcactca agcgagtccc gctgctgccg atatcccctc       60

acagtggact ttgaggcttt cggctgggac tggatcatcg cacctaagcg ctacaaggcc      120

aactactgct ccggccagtg cgagtacatg ttcatgcaaa aatatccgca tacccatttg      180

gtgcagcagg ccaatccaag aggctctgct gggccctgtt gtacccccac caagatgtcc      240

ccaatcaaca tgctctactt caatgacaag cagcagatta tctacggcaa gatccctggc      300

atggtggtgg atcgctgtgg ctgctct                                          327


<210>  3594
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  3594
gcgcgtgcgc gcaacgggga ccactgtccg ctcgggcccg ggcgttgctg ccgtctgcac       60

acggtccgcg cgtcgctgga agacctgggc tgggccgatt gggtgctgtc gccacgggag      120

gtgcaagtga ccatgtgcat cggcgcgtgc ccgagccagt tccgggcggc aaacatgcac      180

gcgcagatca agacgagcct gcaccgcctg aagcccgaca cggtgccagc gccctgctgc      240

gtgcccgcca gctacaatcc catggtgctc attcaaaaga ccgacaccgg ggtgtcgctc      300

cagacctatg atgacttgtt agccaaagac tgccactgca ta                         342


<210>  3595
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  3595
agcgccgggg ctggcagcca ctgtcaaaag acctccctgc gggtaaactt cgaggacatc       60

ggctgggaca gctggatcat tgcacccaag gagtatgaag cctacgagtg taagggcggc      120

tgcttcttcc ccttggctga cgatgtgacg ccgacgaaac acgctatcgt gcagaccctg      180

gtgcatctca agttccccac aaaggtgggc aaggcctgct gtgtgcccac caaactgagc      240

cccatctccg tcctctacaa ggatgacatg ggggtgccca ccctcaagta ccattacgag      300

ggcatgagcg tggcagagtg tgggtgcagg                                       330


<210>  3596
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  3596
gcagccatcc ctgtccccaa gctttcttgt aagaacctct gccaccgtca ccagctattc       60

attaacttcc gggacctggg ttggcacaag tggatcattg cccccaaggg gttcatggca      120

aattactgcc atggagagtg tcccttctca ctgaccatct ctctcaacag ctccaattat      180

gctttcatgc aagccctgat gcatgccgtt gacccagaga tcccccaggc tgtgtgtatc      240

cccaccaagc tgtctcccat ttccatgctc taccaggaca ataatgacaa tgtcattcta      300

cgacattatg aagacatggt agtcgatgaa tgtgggtgtg gg                         342


<210>  3597
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3597
gccccactgg ccactcgcca gggcaagcga cccagcaaga accttaaggc tcgctgcagt       60

cggaaggcac tgcatgtcaa cttcaaggac atgggctggg acgactggat catcgcaccc      120

cttgagtacg aggctttcca ctgcgagggg ctgtgcgagt tcccattgcg ctcccacctg      180

gagcccacga atcatgcagt catccagacc ctgatgaact ccatggaccc cgagtccaca      240

ccacccacct gctgtgttcc cacgcggctg agtcccatca gcatcctctt cattgactct      300

gccaacaacg tggtgtataa gcagtatgag gacatggtcg tggagtcgtg tggctgcagg      360


<210>  3598
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3598
acggccttcg ccagtcgcca tggcaagcgg cacggcaaga agtccaggct acgctgcagc       60

aagaagcccc tgcacgtgaa cttcaaggag ctgggctggg acgactggat tatcgcgccc      120

ctggagtacg aggcctatca ctgcgagggt gtatgcgact tcccgctgcg ctcgcacctg      180

gagcccacca accacgccat catccagacg ctgatgaact ccatggaccc cggctccacc      240

ccgcccagct gctgcgtgcc caccaaattg actcccatca gcattctata catcgacgcg      300

ggcaataatg tggtctacaa gcagtacgag gacatggtgg tggagtcgtg cggctgcagg      360


<210>  3599
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  3599
gattttggtc ttgactgtga tgagcactca acagaatcac gatgctgtcg ttaccctcta       60

actgtggatt ttgaagcttt tggatgggat tggattatcg ctcctaaaag atataaggcc      120

aattactgct ctggagagtg tgaatttgta tttttacaaa aatatcctca tactcatctg      180

gtacaccaag caaaccccag aggttcagca ggcccttgct gtactcccac aaagatgtct      240

ccaattaata tgctatattt taatggcaaa gaacaaataa tatatgggaa aattccagcg      300

atggtagtag accgctgtgg gtgctca                                          327


<210>  3600
<211>  405
<212>  DNA
<213>  Homo Sapiens

<400>  3600
ggtcaggaaa ctgtcagttc tgaattgaag aagcccttgg gcccagcttc cttcaatctg       60

agtgaatact tcagacaatt tcttcttccc caaaatgagt gtgagctcca tgactttaga      120

cttagcttta gtcagctgaa gtgggacaac tggattgtgg ctccgcacag gtacaaccct      180

cgatactgta aaggggactg tccaagggca gttggacatc ggtatggctc tccagttcac      240

accatggtac agaacatcat ctatgagaag ctggactcct cagtgccaag accgtcatgt      300

gtacctgcca aatacagccc cttgagtgtt ttgaccattg agcccgatgg ctcaattgcc      360

tataaagagt acgaagatat gatagctaca aagtgcacct gtcgt                      405


<210>  3601
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  3601
tcaccagata aacaaatggc agtgcttcct agaagagagc ggaatcggca ggctgcagct       60

gccaacccag agaattccag aggaaaaggt cggagaggcc agaggggcaa aaaccggggt      120

tgtgtcttaa ctgcaataca tttaaatgtc actgacttgg gtctgggcta tgaaaccaag      180

gaggaactga tttttaggta ctgcagcggc tcttgcgatg cagctgagac aacgtacgac      240

aaaatattga aaaacttatc cagaaataga aggctggtga gtgacaaagt agggcaggca      300

tgttgcagac ccatcgcctt tgatgatgac ctgtcgtttt tagatgataa cctggtttac      360

catattctaa gaaagcattc cgctaaaagg tgtggatgta tc                         402


<210>  3602
<211>  1200
<212>  DNA
<213>  Homo Sapiens

<400>  3602
gaccgcctgg attgcgtgaa agccagtgat cagtgcctga aggagcagag ctgcagcacc       60

aagtaccgca cgctaaggca gtgcgtggcg ggcaaggaga ccaacttcag cctggcatcc      120

ggcctggagg ccaaggatga gtgccgcagc gccatggagg ccctgaagca gaagtcgctc      180

tacaactgcc gctgcaagcg gggtatgaag aaggagaaga actgcctgcg catttactgg      240

agcatgtacc agagcctgca gggaaatgat ctgctggagg attccccata tgaaccagtt      300

aacagcagat tgtcagatat attccgggtg gtcccattca tatcagtgga gcacattccc      360

aaagggaaca actgcctgga tgcagcgaag gcctgcaacc tcgacgacat ttgcaagaag      420

tacaggtcgg cgtacatcac cccgtgcacc accagcgtgt ccaatgatgt ctgcaaccgc      480

cgcaagtgcc acaaggccct ccggcagttc tttgacaagg tcccggccaa gcacagctac      540

ggaatgctct tctgctcctg ccgggacatc gcctgcacag agcggaggcg acagaccatc      600

gtgcctgtgt gctcctatga agagagggag aagcccaact gtttgaattt gcaggactcc      660

tgcaagacga attacatctg cagatctcgc cttgcggatt tttttaccaa ctgccagcca      720

gagtcaaggt ctgtcagcag ctgtctaaag gaaaactacg ctgactgcct cctcgcctac      780

tcggggctta ttggcacagt catgaccccc aactacatag actccagtag cctcagtgtg      840

gccccatggt gtgactgcag caacagtggg aacgacctag aagagtgctt gaaatttttg      900

aatttcttca aggacaatac atgtcttaaa aatgcaattc aagcctttgg caatggctcc      960

gatgtgaccg tgtggcagcc agccttccca gtacagacca ccactgccac taccaccact     1020

gccctccggg ttaagaacaa gcccctgggg ccagcagggt ctgagaatga aattcccact     1080

catgttttgc caccgtgtgc aaatttacag gcacagaagc tgaaatccaa tgtgtcgggc     1140

aatacacacc tctgtatttc caatggtaat tatgaaaaag aaggtctcgg tgcttccagc     1200


<210>  3603
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  3603
agcccttcct ccctgcaggg ccccgagctc cacggctggc gccccccagt ggactgtgtc       60

cgggccaatg agctgtgtgc cgccgaatcc aactgcagct ctcgctaccg cactctgcgg      120

cagtgcctgg caggccgcga ccgcaacacc atgctggcca acaaggagtg ccaggcggcc      180

ttggaggtct tgcaggagag cccgctgtac gactgccgct gcaagcgggg catgaagaag      240

gagctgcagt gtctgcagat ctactggagc atccacctgg ggctgaccga gggtgaggag      300

ttctacgaag cctcccccta tgagccggtg acctcccgcc tctcggacat cttcaggctt      360

gcttcaatct tctcagggac aggggcagac ccggtggtca gcgccaagag caaccattgc      420

ctggatgctg ccaaggcctg caacctgaat gacaactgca agaagctgcg ctcctcctac      480

atctccatct gcaaccgcga gatctcgccc accgagcgct gcaaccgccg caagtgccac      540

aaggccctgc gccagttctt cgaccgggtg cccagcgagt acacctaccg catgctcttc      600

tgctcctgcc aagaccaggc gtgcgctgag cgccgccggc aaaccatcct gcccagctgc      660

tcctatgagg acaaggagaa gcccaactgc ctggacctgc gtggcgtgtg ccggactgac      720

cacctgtgtc ggtcccggct ggccgacttc catgccaatt gtcgagcctc ctaccagacg      780

gtcaccagct gccctgcgga caattaccag gcgtgtctgg gctcttatgc tggcatgatt      840

gggtttgaca tgacacctaa ctatgtggac tccagcccca ctggcatcgt ggtgtccccc      900

tggtgcagct gtcgtggcag cgggaacatg gaggaggagt gtgagaagtt cctcagggac      960

ttcaccgaga acccatgcct ccggaacgcc atccaggcct ttggcaacgg cacggacgtg     1020

aacgtgtccc caaaaggccc ctcgttccag gccacccagg cccctcgggt ggagaagacg     1080

ccttctttgc cagatgacct cagtgacagt accagcttgg ggaccagtgt catcaccacc     1140

tgcacgtctg tccaggagca ggggctgaag gccaacaact ccaaagagtt aagcatgtgc     1200

ttcacagagc tcacgacaaa tatcatccca gggagtaaca aggtgatcaa acctaactca     1260

ggccccagc                                                             1269


<210>  3604
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  3604
gacccccttc ccacagaaag ccgactcatg aacagctgtc tccaggccag gaggaagtgc       60

caggctgatc ccacctgcag tgctgcctac caccacctgg attcctgcac ctctagcata      120

agcaccccac tgccctcaga ggagccttcg gtccctgctg actgcctgga ggcagcacag      180

caactcagga acagctctct gataggctgc atgtgccacc ggcgcatgaa gaaccaggtt      240

gcctgcttgg acatctattg gaccgttcac cgtgcccgca gccttggtaa ctatgagctg      300

gatgtctccc cctatgaaga cacagtgacc agcaaaccct ggaaaatgaa tctcagcaaa      360

ctgaacatgc tcaaaccaga ctcagacctc tgcctcaagt ttgccatgct gtgtactctc      420

aatgacaagt gtgaccggct gcgcaaggcc tacggggagg cgtgctccgg gccccactgc      480

cagcgccacg tctgcctcag gcagctgctc actttcttcg agaaggccgc cgagccccac      540

gcgcagggcc tgctactgtg cccatgtgcc cccaacgacc ggggctgcgg ggagcgccgg      600

cgcaacacca tcgcccccaa ctgcgcgctg ccgcctgtgg cccccaactg cctggagctg      660

cggcgcctct gcttctccga cccgctttgc agatcacgcc tggtggattt ccagacccac      720

tgccatccca tggacatcct aggaacttgt gcaacagagc agtccagatg tctacgagca      780

tacctggggc tgattgggac tgccatgacc cccaactttg tcagcaatgt caacaccagt      840

gttgccttaa gctgcacctg ccgaggcagt ggcaacctgc aggaggagtg tgaaatgctg      900

gaagggttct tctcccacaa cccctgcctc acggaggcca ttgcagctaa gatgcgtttt      960

cacagccaac tcttctccca ggactggcca caccctacct ttgctgtgat ggcacaccag     1020

aatgaaaac                                                             1029


<210>  3605
<211>  774
<212>  DNA
<213>  Homo Sapiens

<400>  3605
gtcggaggga accgatgtgt ggacgcggcc gaagcctgca cggcggacgc gcggtgccag       60

cgtttgcgct ccgagtatgt ggcgcagtgc ctgggccggg ctgcgcaggg gggctgtccc      120

cgcgcccgct gccgccgggc cctgcgccgc ttcttcgccc gcgggccgcc cgcgctcacc      180

cacgcactgc tcttctgccc gtgcgcgggc cccgcgtgcg ccgagcgtcg gcgccagacc      240

ttcgtgccct cctgcgcctt ttcggggccc ggccccgcgc cgccctcctg ccttgagccc      300

ttaaacttct gcgagcgcag ccgggtctgc aggtgcgcgc gggcggcggc ggggccgtgg      360

cgagggtggg gacggggcct ctctccggct caccgccctc ccgccgcgca ggcctcgcct      420

cctggccttt caggtctcgt gcaccccagc gcccagcgcc cccgacggct gcctgctgga      480

ccagggcgcc cgctgcctgc gcgcctacgc gggcctcgtg gggtccccgc aggcaccgcc      540

gtcaccccta actacgtgga caacgtgagc gcgcgcgtgg cgccctggtg cgactgcgga      600

gccagcggga accggcgtga ggactgcgaa gccttccggg ggctctttac caggaaccgc      660

tgcttggatg gtgccattca ggcctttgcc agcgggtggc ccccagtcct gctggaccag      720

ctgaaccccc agggagaccc ggagcacagc ctcctgcagg tgtcctccac aggc            774


<210>  3606
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  3606
tttagcggct cagaagctac tgctgctatc ctatctagag ctccgtggtc cttacaatcc       60

gtaaacccag gtttgaaaac aaacagcagc aaagaaccca aatttacgaa atgtaggtct      120

cccgagaggg aaactttctc atgccattgg actgacgaag ttcatcacgg gaccaaaaac      180

cttggcccta tacagttgtt ttacacgaga agaaatacgc aagaatggac gcaagagtgg      240

aaagagtgcc ctgactatgt ctccgcagga gagaactctt gttatttcaa ctcatcattt      300

acatccattt ggataccata ttgcattaaa ctgacgagta acggcggtac tgtggacgag      360

aagtgcttct ccgtcgatga gatagtgcaa ccagacccgc cgatagcgct aaactggacc      420

ttgctaaatg tttccttgac tggcatccat gcggacatac aggtcaggtg ggaagcccca      480

agaaacgcgg atattcaaaa agggtggatg gtactagagt atgaattaca atacaaagaa      540

gttaatgaga ccaaatggaa aatgatggac ccgattttga ctacatccgt acctgtatat      600

tctttgaaag tggacaaaga atatgaagtt agggtcaggt ccaagcagag aaatagtggt      660

aactacggag aattctccga agtattgtac gtgacgctgc cccagatgag ccagtttacg      720

tgcgaagagg atttttac                                                    738


<210>  3607
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  3607
caaagaccta caggaggacc gggctgcggc cctggaaggt tgctacttgg cacaggcacc       60

gatgctcgtt gctgccgtgt acacaccact agatgttgca gggactaccc cggagaggag      120

tgttgtagcg aatgggactg tatgtgcgtc caaccagaat ttcactgtgg tgatccctgt      180

tgcacgactt gcaggcatca cccgtgtccg ccgggtcaag gcgtccaatc tcagggaaag      240

ttctcctttg gtttccagtg cattgactgt gcctcaggca ccttttcagg gggtcacgaa      300

ggtcactgca aaccttggac ggactgtaca caattcggtt ttctgacagt gttcccaggc      360

aataagactc ataatgccgt atgcgtccca ggaagcccgc cggcagaacc t               411


<210>  3608
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  3608
agtgccacca tgcgcgctca gtggacttac agtttgagat gccatgactg tgcggtcata       60

aatgacttca actgtcccaa cattagagta tgtccgtatc atattaggcg ctgtatgaca      120

atctccattc gcataaattc tcgtgaacta cttgtttata agaactgtac aaacaactgc      180

acatttgtat atgcagctga acagcctcct gaagccccag gaaaaatctt caaaactaat      240

agcttctact gggtttgttg ttgtaatagc atggtttgca atgcaggagg acctactaat      300

cttgaaaggg acatgttacc cgatgaagta actgaggagg agcttcca                   348


<210>  3609
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  3609
cgtctgagcc ctgagtacta cgacctggca agagcccacc tgcgtgatga ggagaaatcc       60

tgcccgtgcc tggcccagga gggcccccag ggtgacctgt tgaccaaaac acaggagctg      120

ggccgtgact acaggacctg tctgacgata gtccaaaaac tgaagaagat ggtggataag      180

cccacccaga gaagtgtttc caatgctgcg acccgggtgt gtaggacggg gaggtcacga      240

tggcgcgacg tctgcagaaa tttcatgagg aggtatcagt ctagagttac ccagggcctc      300

gtggccggag aaactgccca gcagatctgt gaggacctca ggttgtgtat accttctaca      360

ggtcccctc                                                              369


<210>  3610
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  3610
caccccatct gtgaggtctc caaagtggcc agccacctag aagtgaactg tgacaagagg       60

aatctgacag cgctgcctcc agacctgccg aaagacacaa ccatcctcca cctgagtgag      120

aacctcctgt acaccttctc cctggcaacc ctgatgcctt acactcgcct cactcagctg      180

aacctagata ggtgcgagct caccaagctc caggtcgatg ggacgctgcc agtgctgggg      240

accctggatc tatcccacaa tcagctgcaa agcctgccct tgctagggca gacactgcct      300

gctctcaccg tcctggacgt ctccttcaac cggctgacct cgctgcctct tggtgccctg      360

cgtggtcttg gcgaactcca agagctctac ctgaaaggca atgagctgaa gaccctgccc      420

ccagggctcc tgacgcccac acccaagctg gagaagctca gtctggctaa caacaacttg      480

actgagctcc ccgctgggct cctgaatggg ctggagaatc tcgacaccct tctcctccaa      540

gagaactcgc tgtatacaat accaaagggc ttttttgggt cccacctcct gccttttgct      600

tttctccacg ggaacccctg gttatgcaac tgtgagatcc tctattttcg tcgctggctg      660

caggacaatg ctgaaaatgt ctacgtatgg aagcaaggtg tggacgtcaa ggccatgacc      720

tctaacgtgg ccagtgtgca gtgtgacaat tcagacaagt ttcccgtcta caaataccca      780

ggaaaggggt gccccaccct tggtgatgaa ggtgacacag acctatatga ttactaccca      840

gaagaggaca ctgagggcga taaggtgcgt gccacaagga ctgtggtcaa gttccccacc      900

aaagcccata caaccccctg gggtctattc tactcatggt ccactgcttc tctagacagc      960

caaatgccct cctccttgca tccaacacaa gaatccacta aggagcagac cacattccca     1020

cctagatgga ccccaaattt cacacttcac atggaatcca tcacattctc caaaactcca     1080

aaatccacta ctgaaccaac cccaagcccg accacctcag agcccgtccc ggagcccgcc     1140

ccaaacatga ccaccctgga gcccactcca agcccgacca ccccagagcc cacctcagag     1200

cccgccccca gcccgaccac cccggagccc accccaatcc cgaccatcgc cacaagcccg     1260

accatcctgg tgtctgccac aagcctgatc actccaaaaa gcacattttt aactaccaca     1320

aaacccgtat cactcttaga atccaccaaa aaaaccatcc ctgaacttga tcagccacca     1380

aagctccgtg gggtgctcca agggcatttg gagagctcca gaaatgaccc ttttctccac     1440

cccgactttt gctgcctcct ccccctg                                         1467


<210>  3611
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  3611
cctgctccgt gttcatgtgc cggtacttta gtcgactgtg gtagaagggg attgacatgg       60

gccagccttc ccacagcttt tcctgtcgat accactgaat tagttctaac aggtaacaat      120

ctgaccgctc tgccacccgg acttttagac gctcttcccg cactaaggac agcacacttg      180

ggggctaacc cgtggagatg cgattgtcgt ctggtccctt tacgtgcgtg gctggccggg      240

cgtcccgaaa gggctccata tcgtgaccta agatgtgtcg cccctccggc gttgagaggg      300

cgtctacttc cctacctagc agaagacgag cttagggccg cgtgtgctcc gggtcccctt      360

tgc                                                                    363


<210>  3612
<211>  981
<212>  DNA
<213>  Homo Sapiens

<400>  3612
gtggaggaca agtgtgagaa ggcctgccgc cccgaggagg agtgccttgc cctcaacagc       60

acctggggct gtttctgcag acaggacctc aatagttctg atgtccacag tttgcagcct      120

cagctagact gtgggcccag ggagatcaag gtgaaggtgg acaaatgttt gctgggaggc      180

ctgggtttgg gggaggaggt cattgcctac ctgcgagacc caaactgcag cagcatcttg      240

cagacagagg agaggaactg ggtatctgtg accagccccg tccaggctag tgcctgcagg      300

aacattctgg agagaaatca aacccatgcc atctacaaaa acaccctctc cttggtcaat      360

gatttcatca tcagagacac catcctcaac atcaacttcc aatgtgccta cccactggac      420

atgaaagtca gcctccaagc tgccttgcag cccattgtaa gttccctgaa cgtcagtgtg      480

gacgggaatg gagagttcat tgtcaggatg gccctcttcc aagaccagaa ctacacgaat      540

ccttaccaag gggatgcagt tgaactgtct gttgagtccg tgctgtatgt gggtgccatc      600

ttggaacaag gggacacctc ccggtttaac ctggtgttga ggaactgcta tgccaccccc      660

actgaagaca aggctgacct tgtgaagtat ttcatcatca gaaacagctg ctcaaatcaa      720

cgtgattcca ccatccacgt ggaggagaat gggcagtcct cggaaagccg gttctcagtt      780

cagatgttca tgtttgctgg acattatgac ctagttttcc tgcattgtga gattcatctc      840

tgtgattctc ttaatgaaca gtgccagcct tcttgctcaa gaagtcaagt ccgcagtgaa      900

gtaccggcca tcgacctagc ccgggttcta gatttggggc ccatcactcg gagaggtgca      960

cagtctcccg gtgtcatgaa t                                                981


<210>  3613
<211>  1521
<212>  DNA
<213>  Homo Sapiens

<400>  3613
cagcccttcc cctgtccgcc agcttgcaag tgtgtcttcc gggacgccgc gcagtgctcg       60

gggggcgacg tggcgcgcat ctccgcgcta ggcctgccca ccaacctcac gcacatcctg      120

ctcttcggaa tgggccgcgg cgtcctgcag agccagagct tcagcggcat gaccgtcctg      180

cagcgcctca tgatctccga cagccacatt tccgccgttg cccccggcac cttcagtgac      240

ctgataaaac tgaaaaccct gaggctgtcg cgcaacaaaa tcacgcatct tccaggtgcg      300

ctgctggata agatggtgct cctggagcag ttgtttttgg accacaatgc gctaaggggc      360

attgaccaaa acatgtttca gaaactggtt aacctgcagg agctcgctct gaaccagaat      420

cagctcgatt tccttcctgc cagtctcttc acgaatctgg agaacctgaa gttgttggat      480

ttatcgggaa acaacctgac ccacctgccc aaggggttgc ttggagcaca ggctaagctc      540

gagagacttc tgctccactc gaaccgcctt gtgtctctgg attcggggct gttgaacagc      600

ctgggcgccc tgacggagct gcagttccac cgaaatcaca tccgttccat cgcacccggg      660

gccttcgacc ggctcccaaa cctcagttct ttgacgcttt cgagaaacca ccttgcgttt      720

ctcccctctg cgctctttct tcattcgcac aatctgactc tgttgactct gttcgagaac      780

ccgctggcag agctcccggg ggtgctcttc ggggagatgg ggggcctgca ggagctgtgg      840

ctgaaccgca cccagctgcg caccctgccc gccgccgcct tccgcaacct gagccgcctg      900

cggtacttag gggtgactct gagcccgcgg ctgagcgcgc ttccgcaggg cgccttccag      960

ggccttggcg agctccaggt gctcgccctg cactccaacg gcctgaccgc cctccccgac     1020

ggcttgctgc gcggcctcgg caagctgcgc caggtgtccc tgcgccgcaa caggctgcgc     1080

gccctgcccc gtgccctctt ccgcaatctc agcagcctgg agagcgtcca gctcgaccac     1140

aaccagctgg agaccctgcc tggcgacgtg tttggggctc tgccccggct gacggaggtc     1200

ctgttggggc acaactcctg gcgctgcgac tgtggcctgg ggcccttcct ggggtggctg     1260

cggcagcacc taggcctcgt gggcggggaa gagcccccac ggtgcgcagg ccctggggcg     1320

cacgccggcc tgccgctctg ggccctgccg gggggtgacg cggagtgccc gggcccccgg     1380

ggcccgcctc cccgccccgc tgcggacagc tcctcggaag cccctgtcca cccagccttg     1440

gctcccaaca gctcagaacc ctgggtgtgg gcccagccgg tgaccacggg caaaggtcaa     1500

gatcatagtc cgttctgggg g                                               1521


<210>  3614
<211>  741
<212>  DNA
<213>  Homo Sapiens

<400>  3614
cagagtggac cgctccccaa gccctccctc caggctctgc ccagctccct ggtgcccctg       60

gagaagccag tgaccctccg gtgccaggga cctccgggcg tggacctgta ccgcctggag      120

aagctgagtt ccagcaggta ccaggatcag gcagtcctct tcatcccggc catgaagaga      180

agtctggctg gacgctaccg ctgctcctac cagaacggaa gcctctggtc cctgcccagc      240

gaccagctgg agctcgttgc cacgggagtt tttgccaaac cctcgctctc agcccagccc      300

ggcccggcgg tgtcgtcagg aggggacgta accctacagt gtcagactcg gtatggcttt      360

gaccaatttg ctctgtacaa ggaaggggac cctgcgccct acaagaatcc cgagagatgg      420

taccgggcta gtttccccat catcacggtg accgccgccc acagcggaac ctaccgatgc      480

tacagcttct ccagcaggga cccatacctg tggtcggccc ccagcgaccc cctggagctt      540

gtggtcacag gaacctctgt gacccccagc cggttaccaa cagaaccacc ttcctcggta      600

gcagaattct cagaagccac cgctgaactg accgtctcat tcacaaacaa agtcttcaca      660

actgagactt ctaggagtat caccaccagt ccaaaggagt cagactctcc agctggtcct      720

gcccgccagt actacaccaa g                                                741


<210>  3615
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  3615
accaaggact gccccagccc atgtacctgc cgcgccctgg aaaccatggg gctgtgggtg       60

gactgcaggg gccacggact cacggccctg cctgccctgc cggcccgcac ccgccacctt      120

ctgctggcca acaacagcct tcagtccgtg cccccgggag cctttgacca cctgccccag      180

ctgcagaccc tcgatgtgac gcagaacccc tggcactgtg actgcagcct cacctatctg      240

cgcctctggc tggaggaccg cacgcccgag gccctgctgc aggtccgctg tgccagcccc      300

agcctcgctg cccatggccc gctgggccgg ctgacaggct accagctggg cagctgtggc      360

tggcagctgc aggcgtcctg ggtgcgcccg ggg                                   393


<210>  3616
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  3616
atctctgtgg aaactccgca ggacgttctt cgggcttcgc agggaaagag tgtcaccctg       60

ccctgcacct accacacttc cacctccagt cgagagggac ttattcaatg ggataagctc      120

ctcctcactc atacggaaag ggtggtcatc tggccgtttt caaacaaaaa ctacatccat      180

ggtgagcttt ataagaatcg cgtcagcata tccaacaatg ctgagcagtc cgatgcctcc      240

atcaccattg atcagctgac catggctgac aacggcacct acgagtgttc tgtctcgctg      300

atgtcagacc tggagggcaa caccaagtca cgtgtccgcc tgttggtcct cgtgccaccc      360

tccaaaccag aatgcggcat cgagggagag accataattg ggaacaacat ccagctgacc      420

tgccaatcaa aggagggctc accaacccct cagtacagct ggaagaggta caacatcctg      480

aatcaggagc agcccctggc ccagccagcc tcaggtcagc ctgtctccct gaagaatatc      540

tccacagaca catcgggtta ctacatctgt acctccagca atgaggaggg gacgcagttc      600

tgcaacatca cggtggccgt cagatctccc tccatgaacg tg                         642


<210>  3617
<211>  1671
<212>  DNA
<213>  Homo Sapiens

<400>  3617
gccgctctca cccgggaccc ccagttccag aagctgcagc aatggtaccg cgagcaccgc       60

tccgagctga acctgcgccg cctcttcgat gccaacaagg accgcttcaa ccacttcagc      120

ttgaccctca acaccaacca tgggcatatc ctggtggatt actccaagaa cctggtgacg      180

gaggacgtga tgcggatgct ggtggacttg gccaagtcca ggggcgtgga ggccgcccgg      240

gagcggatgt tcaatggtga gaagatcaac tacaccgagg gtcgagccgt gctgcacgtg      300

gctctgcgga accggtcaaa cacacccatc ctggtagacg gcaaggatgt gatgccagag      360

gtcaacaagg ttctggacaa gatgaagtct ttctgccagc gtgtccggag cggtgactgg      420

aaggggtaca caggcaagac catcacggac gtcatcaaca ttggcattgg cggctccgac      480

ctgggacccc tcatggtgac tgaagccctt aagccatact cttcaggagg tccccgcgtc      540

tggtatgtct ccaacattga tggaactcac attgccaaaa ccctggccca gctgaacccc      600

gagtcctccc tgttcatcat tgcctccaag acctttacta cccaggagac catcacgaat      660

gcagagacgg cgaaggagtg gtttctccag gcggccaagg atccttctgc agtggcgaag      720

cactttgttg ccctgtctac taacacaacc aaagtgaagg agtttggaat tgaccctcaa      780

aacatgttcg agttctggga ttgggtggga ggacgctact cgctgtggtc ggccatcgga      840

ctctccattg ccctgcacgt gggttttgac aacttcgagc agctgctctc gggggctcac      900

tggatggacc agcacttccg cacgacgccc ctggagaaga acgcccccgt cttgctggcc      960

ctgctgggta tctggtacat caactgcttt gggtgtgaga cacacgccat gctgccctat     1020

gaccagtacc tgcaccgctt tgctgcgtac ttccagcagg gcgacatgga gtccaatggg     1080

aaatacatca ccaaatctgg aacccgtgtg gaccaccaga caggccccat tgtgtggggg     1140

gagccaggga ccaatggcca gcatgctttt taccagctca tccaccaagg caccaagatg     1200

ataccctgtg acttcctcat cccggtccag acccagcacc ccatacggaa gggtctgcat     1260

cacaagatcc tcctggccaa cttcttggcc cagacagagg ccctgatgag gggaaaatcg     1320

acggaggagg cccgaaagga gctccaggct gcgggcaaga gtccagagga ccttgagagg     1380

ctgctgccac ataaggtctt tgaaggaaat cgcccaacca actctattgt gttcaccaag     1440

ctcacaccat tcatgcttgg agccttggtc gccatgtatg agcacaagat cttcgttcag     1500

ggcatcatct gggacatcaa cagctttgac cagtggggag tggagctggg aaagcagctg     1560

gctaagaaaa tagagcctga gcttgatggc agtgctcaag tgacctctca cgacgcttct     1620

accaatgggc tcatcaactt catcaagcag cagcgcgagg ccagagtcca a              1671


<210>  3618
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  3618
cagacacagc aggaggaaga ggaagaggac gaggaccacg ggccagatga ctacgacgag       60

gaagatgagg atgaggtgga agaggaggag accaacaggc tccctggtgg caggagcaga      120

gtgctgctgc ggtgctacac ctgcaagtcc ctgcccaggg acgagcgctg caacctgacg      180

cagaactgct cacatggcca gacctgcaca accctcattg cccacgggaa caccgagtca      240

ggcctcctga ccacccactc cacgtggtgc acagacagct gccagcccat caccaagacg      300

gtggagggga cccaggtgac catgacctgc tgccagtcca gcctgtgcaa tgtcccaccc      360

tggcaaagct cccgagtcca ggacccaaca ggc                                   393


<210>  3619
<211>  1395
<212>  DNA
<213>  Homo Sapiens

<400>  3619
gccaaacgat ttcatgatgt gctgggcaat gaaagacctt ctgcttacat gagggagcac       60

aatcaattaa atggctggtc ttctgatgaa aatgactgga atgaaaaact ctacccagtg      120

tggaagcggg gagacatgag gtggaaaaac tcctggaagg gaggccgtgt gcaggcggtc      180

ctgaccagtg actcaccagc cctcgtgggc tcaaatataa catttgcggt gaacctgata      240

ttccctagat gccaaaagga agatgccaat ggcaacatag tctatgagaa gaactgcaga      300

aatgaggctg gtttatctgc tgatccgtat gtttacaact ggacagcatg gtcagaggac      360

agtgacgggg aaaatggcac cggccaaagc catcataacg tcttccctga tgggaaacct      420

tttcctcacc accccggatg gagaagatgg aatttcatct acgtcttcca cacacttggt      480

cagtatttcc agaaattggg acgatgttca gtgagagttt ctgtgaacac agccaatgtg      540

acacttgggc ctcaactcat ggaagtgact gtctacagaa gacatggacg ggcatatgtt      600

cccatcgcac aagtgaaaga tgtgtacgtg gtaacagatc agattcctgt gtttgtgact      660

atgttccaga agaacgatcg aaattcatcc gacgaaacct tcctcaaaga tctccccatt      720

atgtttgatg tcctgattca tgatcctagc cacttcctca attattctac cattaactac      780

aagtggagct tcggggataa tactggcctg tttgtttcca ccaatcatac tgtgaatcac      840

acgtatgtgc tcaatggaac cttcagcctt aacctcactg tgaaagctgc agcaccagga      900

ccttgtccgc caccgccacc accacccaga ccttcaaaac ccaccccttc tttagcaact      960

actctaaaat cttatgattc aaacacccca ggacctgctg gtgacaaccc cctggagctg     1020

agtaggattc ctgatgaaaa ctgccagatt aacagatatg gccactttca agccaccatc     1080

acaattgtag agggaatctt agaggttaac atcatccaga tgacagacgt cctgatgccg     1140

gtgccatggc ctgaaagctc cctaatagac tttgtcgtga cctgccaagg gagcattccc     1200

acggaggtct gtaccatcat ttctgacccc acctgcgaga tcacccagaa cacagtctgc     1260

agccctgtgg atgtggatga gatgtgtctg ctgactgtga gacgaacctt caatgggtct     1320

gggacgtact gtgtgaacct caccctgggg gatgacacaa gcctggctct cacgagcacc     1380

ctgatttctg ttcct                                                      1395


<210>  3620
<211>  1887
<212>  DNA
<213>  Homo Sapiens

<400>  3620
ctgcagggcg ggatgctgta cccccaggag agcccgtcgc gggagtgcaa ggagctggac       60

ggcctctgga gcttccgcgc cgacttctct gacaaccgac gccggggctt cgaggagcag      120

tggtaccggc ggccgctgtg ggagtcaggc cccaccgtgg acatgccagt tccctccagc      180

ttcaatgaca tcagccagga ctggcgtctg cggcattttg tcggctgggt gtggtacgaa      240

cgggaggtga tcctgccgga gcgatggacc caggacctgc gcacaagagt ggtgctgagg      300

attggcagtg cccattccta tgccatcgtg tgggtgaatg gggtcgacac gctagagcat      360

gaggggggct acctcccctt cgaggccgac atcagcaacc tggtccaggt ggggcccctg      420

ccctcccggc tccgaatcac tatcgccatc aacaacacac tcacccccac caccctgcca      480

ccagggacca tccaatacct gactgacacc tccaagtatc ccaagggtta ctttgtccag      540

aacacatatt ttgacttttt caactacgct ggactgcagc ggtctgtact tctgtacacg      600

acacccacca cctacatcga tgacatcacc gtcaccacca gcgtggagca agacagtggg      660

ctggtgaatt accagatctc tgtcaagggc agtaacctgt tcaagttgga agtgcgtctt      720

ttggatgcag aaaacaaagt cgtggcgaat gggactggga cccagggcca acttaaggtg      780

ccaggtgtca gcctctggtg gccgtacctg atgcacgaac gccctgccta tctgtattca      840

ttggaggtgc agctgactgc acagacgtca ctggggcctg tgtctgactt ctacacactc      900

cctgtgggga tccgcactgt ggctgtcacc aagagccagt tcctcatcaa tgggaaacct      960

ttctatttcc acggtgtcaa caagcatgag gatgcggaca tccgagggaa gggcttcgac     1020

tggccgctgc tggtgaagga cttcaacctg cttcgctggc ttggtgccaa cgctttccgt     1080

accagccact acccctatgc agaggaagtg atgcagatgt gtgaccgcta tgggattgtg     1140

gtcatcgatg agtgtcccgg cgtgggcctg gcgctgccgc agttcttcaa caacgtttct     1200

ctgcatcacc acatgcaggt gatggaagaa gtggtgcgta gggacaagaa ccaccccgcg     1260

gtcgtgatgt ggtctgtggc caacgagcct gcgtcccacc tagaatctgc tggctactac     1320

ttgaagatgg tgatcgctca caccaaatcc ttggacccct cccggcctgt gacctttgtg     1380

agcaactcta actatgcagc agacaagggg gctccgtatg tggatgtgat ctgtttgaac     1440

agctactact cttggtatca cgactacggg cacctggagt tgattcagct gcagctggcc     1500

acccagtttg agaactggta taagaagtat cagaagccca ttattcagag cgagtatgga     1560

gcagaaacga ttgcagggtt tcaccaggat ccacctctga tgttcactga agagtaccag     1620

aaaagtctgc tagagcagta ccatctgggt ctggatcaaa aacgcagaaa atacgtggtt     1680

ggagagctca tttggaattt tgccgatttc atgactgaac agtcaccgac gagagtgctg     1740

gggaataaaa aggggatctt cactcggcag agacaaccaa aaagtgcagc gttccttttg     1800

cgagagagat actggaagat tgccaatgaa accaggtatc cccactcagt agccaagtca     1860

caatgtttgg aaaacagcct gtttact                                         1887


<210>  3621
<211>  1611
<212>  DNA
<213>  Homo Sapiens

<400>  3621
ttctccctga tgtctttatt ggaaagcctg gacccagact ggacccctga ccagtatgat       60

tacagctacg aggattataa tcaggaagag aacaccagta gcacacttac ccacgctgag      120

aatcctgact ggtactacac tgaggaccaa gctgatccat gccagcccaa cccctgtgaa      180

cacggtgggg actgcctcgt ccatgggagc accttcacat gcagctgcct ggctcctttc      240

tctgggaata agtgtcagaa agtgcaaaat acgtgcaagg acaacccatg tggccggggc      300

caatgtctca ttacccagag tcctccctac taccgctgtg tctgtaaaca cccttacaca      360

ggtcccagct gctcccaagt ggttcctgta tgcaggccaa acccctgcca gaatggggct      420

acctgctccc ggcataagcg gagatccaag ttcacctgtg cctgtcccga ccagttcaag      480

gggaaattct gtgaaatagg ttctgatgac tgctatgttg gcgatggcta ctcttaccga      540

gggaaaatga ataggacagt caaccagcat gcgtgccttt actggaactc ccacctcctc      600

ttgcaggaga attacaacat gtttatggag gatgctgaaa cccatgggat tggggaacac      660

aatttctgca gaaacccaga tgcggacgaa aagccctggt gctttattaa agttaccaat      720

gacaaggtga aatgggaata ctgtgatgtc tcagcctgct cagcccagga cgttgcctac      780

ccagaggaaa gccccactga gccatcaacc aagcttccgg ggtttgactc ctgtggaaag      840

actgagatag cagagaggaa gatcaagaga atctatggag gctttaagag cacggcgggc      900

aagcacccat ggcaggcgtc cctccagtcc tcgctgcctc tgaccatctc catgccccag      960

ggccacttct gtggtggggc gctgatccac ccctgctggg tgctcactgc tgcccactgc     1020

accgacataa aaaccagaca tctaaaggtg gtgctagggg accaggacct gaagaaagaa     1080

gaatttcatg agcagagctt tagggtggag aagatattca agtacagcca ctacaatgaa     1140

agagatgaga ttccccacaa tgatattgca ttgctcaagt taaagccagt ggatggtcac     1200

tgtgctctag aatccaaata cgtgaagact gtgtgcttgc ctgatgggtc ctttccctct     1260

gggagtgagt gccacatctc tggctggggt gttacagaaa caggaaaagg gtcccgccag     1320

ctcctggatg ccaaagtcaa gctgattgcc aacactttgt gcaactcccg ccaactctat     1380

gaccacatga ttgatgacag tatgatctgt gcaggaaatc ttcagaaacc tgggcaagac     1440

acctgccagg gtgactctgg aggccccctg acctgtgaga aggacggcac ctactacgtc     1500

tatgggatag tgagctgggg cctggagtgt gggaagaggc caggggtcta cacccaagtt     1560

accaaattcc tgaattggat caaagccacc atcaaaagtg aaagtggctt c              1611


<210>  3622
<211>  75
<212>  DNA
<213>  Homo Sapiens

<400>  3622
gacacccact tccccatctg cattttctgc tgcggctgct gtcatcgatc aaagtgtggg       60

atgtgctgca agacg                                                        75


<210>  3623
<211>  1017
<212>  DNA
<213>  Homo Sapiens

<400>  3623
gatcatcttt cagacaacta tactctggat catgacagag ctattcacat ccaagcagaa       60

aatggccccc atctacttgt ggaagcagag caagccaagg tgttttcaca cagaggtggc      120

aatgttacac tgccatgtaa attttatcga gaccctacag catttggctc aggaatccat      180

aaaatccgaa ttaagtggac caagctaact tcggattacc tcaaggaagt ggatgttttt      240

gtttccatgg gataccacaa aaaaacctat ggaggctacc agggtagagt gtttctgaag      300

ggaggcagtg atagtgatgc ttctctggtc atcacagacc tcactctgga agattatggg      360

agatataagt gtgaggtgat tgaaggatta gaagatgata ctgttgtggt agcactggac      420

ttacaaggtg tggtattccc ttactttcca cgactggggc gctacaatct caattttcac      480

gaggcgcagc aggcgtgtct ggaccaggat gctgtgatcg cctccttcga ccagctgtac      540

gacgcctggc ggggcgggct ggactggtgc aatgccggct ggctcagtga tggctctgtg      600

caatatccca tcacaaagcc cagagagccc tgtgggggcc agaacacagt gcccggagtc      660

aggaactacg gattttggga taaagataaa agcagatatg atgttttctg ttttacatcc      720

aatttcaatg gccgttttta ctatctgatc caccccacca aactgaccta tgatgtagcg      780

gtgcaagctt gtctcaatga tggtgctcag attgcaaaag tgggccagat atttgctgcc      840

tggaaaattc tcggatatga ccgctgtgat gcgggctggt tggcggatgg cagcgtccgc      900

taccccatct ctaggccaag aaggcgctgc agtcctactg aggctgcagt gcgcttcgtg      960

ggtttcccag ataaaaagca taagctgtat ggtgtctact gcttcagagc atacaac        1017


<210>  3624
<211>  942
<212>  DNA
<213>  Homo Sapiens

<400>  3624
gacccagcat cccacccggg cccccactac ctcctgcccc ccatccacga ggtcattcac       60

tctcatcgtg gggccacggc cacgctgccc tgcgtcctgg gcaccacgcc tcccagctac      120

aaggtgcgct ggagcaaggt ggagcctggg gagctccggg aaacgctgat cctcatcacc      180

aacggactgc acgcccgggg gtatgggccc ctgggagggc gcgccaggat gcggaggggg      240

catcgactag acgcctccct ggtcatcgcg ggcgtgcgcc tggaggacga gggccggtac      300

cgctgcgagc tcatcaacgg catcgaggac gagagcgtgg cgctgacctt gagcttggag      360

ggtgtggtgt ttccgtacca acccagccgg ggccggtacc agttcaatta ctacgaggcg      420

aagcaggcgt gcgaggagca ggacggacgc ctggccacct actcccagct ctaccaggct      480

tggaccgagg gtctggactg gtgtaacgcg ggctggctgc tcgagggctc cgtgcgctac      540

cctgtgctca ccgcacgcgc cccgtgcggc ggccgaggcc ggcccgggat ccgcagctac      600

ggaccccgcg accggatgcg cgaccgctac gacgccttct gcttcacctc cgcgctggcg      660

ggccaagtgt tcttcgtgcc cgggcggctg acgctgtctg aagcccacgc ggcgtgccgg      720

cgacgcggcg ccgtggtggc caaggttggg cacctctacg ccgcctggaa gttttcgggg      780

ctagaccagt gcgacggcgg ctggctggct gacggcagtg tgcgcttccc aatcaccacg      840

ccgaggccgc gctgcggggg gctcccggat cccggagtgc gcagtttcgg cttccccagg      900

ccccaacagg cagcctatgg gacctactgc tacgccgaga at                         942


<210>  3625
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  3625
ctgcccttct acaacggctt ctactactcc aacagcgcca acgaccagaa cctaggcaac       60

ggtcatggca aagacctcct taatggagtg aagctggtgg tggagacacc cgaggagacc      120

ctgttcacct accaaggggc cagtgtgatc ctgccctgcc gctaccgcta cgagccggcc      180

ctggtctccc cgcggcgtgt gcgtgtcaaa tggtggaagc tgtcggagaa cggggcccca      240

gagaaggacg tgctggtggc catcgggctg aggcaccgct cctttgggga ctaccaaggc      300

cgcgtgcacc tgcggcagga caaagagcat gacgtctcgc tggagatcca ggatctgcgg      360

ctggaggact atgggcgtta ccgctgtgag gtcattgacg ggctggagga tgaaagcggt      420

ctggtggagc tggagctgcg gggtgtggtc tttccttacc agtcccccaa cgggcgctac      480

cagttcaact tccacgaggg ccagcaggtc tgtgcagagc aggctgcggt ggtggcctcc      540

tttgagcagc tcttccgggc ctgggaggag ggcctggact ggtgcaacgc gggctggctg      600

caggatgcca cggtgcagta ccccatcatg ttgccccggc agccctgcgg tggcccgggc      660

ctggcacctg gcgtgcgaag ctacggcccc cgccaccgcc gcctgcaccg ctatgatgta      720

ttctgcttcg ctactgccct caaggggcgg gtgtactacc tggagcaccc tgagaagctg      780

acgctgacag aggcaaggga ggcctgccag gaagatgatg ccacgatcgc caaggtggga      840

cagctctttg ccgcctggaa gttccatggc ctggaccgct gcgacgctgg ctggctggca      900

gatggtagcg tccgctaccc tgtggttcac ccgcatccta actgtgggcc cccagagcct      960

ggggtccgaa gctttggctt ccccgacccg cagagccgct tgtacggtgt ttactgctac     1020

cgccagcac                                                             1029


<210>  3626
<211>  1119
<212>  DNA
<213>  Homo Sapiens

<400>  3626
cagcgtggcc ggaagaaggt cgtgcacgtg ctggagggtg agtcgggctc ggtagtggta       60

cagacagcgc ctgggcaggt ggtaagccac cgtggtggca ccatcgtctt gccctgccgc      120

taccactatg aggcagccgc ccacggtcac gacggcgtcc ggctcaagtg gacaaaggtg      180

gtggacccgc tggccttcac cgacgtcttc gtggcactag gcccccagca ccgggcattc      240

ggcagctacc gtgggcgggc tgagctgcag ggcgacgggc ctggggatgc ctccctggtc      300

ctccgcaacg tcacgctgca agactacggg cgctatgagt gcgaagtcac caatgagctg      360

gaagatgacg ctggcatggt caagctggac ctggaaggcg tggtctttcc ctaccacccc      420

cgtggaggcc gatacaagct gaccttcgcg gaggcgcagc gcgcgtgcgc cgagcaggac      480

ggcatcctgg catctgcaga acagctgcac gcggcctggc gcgacggcct ggactggtgc      540

aacgcgggct ggttgcgcga cggctcagtg caataccccg tgaaccggcc ccgggagccc      600

tgcggcggcc tgggggggac cgggagtgca gggggcggcg gtgatgccaa cgggggcctg      660

cgcaactacg ggtatcgcca taacgccgag gaacgctacg acgccttctg cttcacgtcc      720

aacctgccgg ggcgcgtgtt cttcctgaag ccgctgcgac ctgtaccctt ctccggagct      780

gcgcgcgcgt gtgctgcgcg tggcgcggcc gtggccaagg tggggcagct gttcgccgcg      840

tggaagctgc agctgctaga ccgctgcacc gcgggttggc tggccgatgg cagtgcgcgc      900

taccccatcg tgaacccgcg agcgcgctgc ggaggccgca ggcctggtgt gcgcagcctc      960

ggcttcccgg acgccacccg acggctcttc ggcgtctact gctaccgcgc tccaggagca     1020

ccggacccgg cacctggcgg ctggggctgg ggctgggcgg gcggcggcgg ctgggcaggg     1080

ggcgcgcgcg atcctgctgc ctggacccct ctgcacgtc                            1119


<210>  3627
<211>  825
<212>  DNA
<213>  Homo Sapiens

<400>  3627
tctgtaaagg ttggtggaga ggcaggtcca tctgtcacac taccctgcca ctacagtgga       60

gctgtcacat ccatgtgctg gaatagaggc tcatgttctc tattcacatg ccaaaatggc      120

attgtctgga ccaatggaac ccacgtcacc tatcggaagg acacacgcta taagctattg      180

ggggaccttt caagaaggga tgtctctttg accatagaaa atacagctgt gtctgacagt      240

ggcgtatatt gttgccgtgt tgagcaccgt gggtggttca atgacatgaa aatcaccgta      300

tcattggaga ttgtgccacc caaggtcacg actactccaa ttgtcacaac tgttccaacc      360

gtcacgactg ttcgaacgag caccactgtt ccaacgacaa cgactgttcc aatgacgact      420

gttccaacga caactgttcc aacaacaatg agcattccaa cgacaacgac tgttctgacg      480

acaatgactg tttcaacgac aacgagcgtt ccaacgacaa cgagcattcc aacaacaaca      540

agtgttccag tgacaacaac tgtctctacc tttgttcctc caatgccttt gcccaggcag      600

aaccatgaac cagtagccac ttcaccatct tcacctcagc cagcagaaac ccaccctacg      660

acactgcagg gagcaataag gagagaaccc accagctcac cattgtactc ttacacaaca      720

gatgggaatg acaccgtgac agagtcttca gatggccttt ggaataacaa tcaaactcaa      780

ctgttcctag aacatagtct actgacggcc aataccacta aagga                      825


<210>  3628
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  3628
tcagaagtgg aatacagagc ggaggtcggt cagaatgcct atctgccctg cttctacacc       60

ccagccgccc cagggaacct cgtgcccgtc tgctggggca aaggagcctg tcctgtgttt      120

gaatgtggca acgtggtgct caggactgat gaaagggatg tgaattattg gacatccaga      180

tactggctaa atggggattt ccgcaaagga gatgtgtccc tgaccataga gaatgtgact      240

ctagcagaca gtgggatcta ctgctgccgg atccaaatcc caggcataat gaatgatgaa      300

aaatttaacc tgaagttggt catcaaacca gccaaggtca cccctgcacc gactctgcag      360

agagacttca ctgcagcctt tccaaggatg cttaccacca ggggacatgg cccagcagag      420

acacagacac tggggagcct ccctgatata aatctaacac aaatatccac attggccaat      480

gagttacggg actctagatt ggccaatgac ttacgggact ctggagcaac catcagaata      540

ggc                                                                    543


<210>  3629
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  3629
gacttgcaag aggcagatct ggaccttttg agagtcactt tatcctccaa gccacaagca       60

ctggccacac caaacaagga ggagcacggg aaaagaaaga agaaaggcaa ggggctaggg      120

aagaagaggg acccatgtct tcggaaatac aaggacttct gcatccatgg agaatgcaaa      180

tatgtgaagg agctccgggc tccctcctgc atctgccacc cgggttacca tggagagagg      240

tgtcatgggc tgagcctc                                                    258


<210>  3630
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3630
gtgaacatca ccagccccgt gcgcctgatc catggcaccg tggggaagtc ggctctgctt       60

tctgtgcagt acagcagtac cagcagcgac aggcctgtag tgaagtggca gctgaagcgg      120

gacaagccag tgaccgtggt gcagtccatt ggcacagagg tcatcggcac cctgcggcct      180

gactatcgag accgtatccg actctttgaa aatggctccc tgcttctcag cgacctgcag      240

ctggccgatg agggcaccta tgaggtcgag atctccatca ccgacgacac cttcactggg      300

gagaagacca tcaaccttac tgtagatgtg cccatttcga ggccacaggt gttggtggct      360

tcaaccactg tgctggagct cagcgaggcc ttcaccttga actgctcaca tgagaatggc      420

accaagccca gctacacctg gctgaaggat ggcaagcccc tcctcaatga ctcgagaatg      480

ctcctgtccc ccgaccaaaa ggtgctcacc atcacccgcg tgctcatgga ggatgacgac      540

ctgtacagct gcatggtgga gaaccccatc agccagggcc gcagcctgcc tgtcaagatc      600

accgtataca gaagaagctc c                                                621


<210>  3631
<211>  960
<212>  DNA
<213>  Homo Sapiens

<400>  3631
ctgaaggtga cagtgccatc acacactgtc catggcgtca gaggtcaggc cctctaccta       60

cccgtccact atggcttcca cactccagca tcagacatcc agatcatatg gctatttgag      120

agaccccaca caatgcccaa atacttactg ggctctgtga ataagtctgt ggttcctgac      180

ttggaatacc aacacaagtt caccatgatg ccacccaatg catctctgct tatcaaccca      240

ctgcagttcc ctgatgaagg caattacatc gtgaaggtca acattcaggg aaatggaact      300

ctatctgcca gtcagaagat acaagtcacg gttgatgatc ctgtcacaaa gccagtggtg      360

cagattcatc ctccctctgg ggctgtggag tatgtgggga acatgaccct gacatgccat      420

gtggaagggg gcactcggct agcttaccaa tggctaaaaa atgggagacc tgtccacacc      480

agctccacct actccttttc tccccaaaac aatacccttc atattgctcc agtaaccaag      540

gaagacattg ggaattacag ctgcctggtg aggaaccctg tcagtgaaat ggaaagtgat      600

atcattatgc ccatcatata ttatggacct tatggacttc aagtgaattc tgataaaggg      660

ctaaaagtag gggaagtgtt tactgttgac cttggagagg ccatcctatt tgattgttct      720

gctgattctc atccccccaa cacctactcc tggattagga ggactgacaa tactacatat      780

atcattaagc atgggcctcg cttagaagtt gcatctgaga aagtagccca gaagacaatg      840

gactatgtgt gctgtgctta caacaacata accggcaggc aagatgaaac tcatttcaca      900

gttatcatca cttccgtagg actggagaag cttgcacaga aaggaaaatc attgtcacct      960


<210>  3632
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3632
cgcttgctgc gttcacactc tctgcactac ctcttcatgg gtgcctcaga gcaggacctt       60

ggtctttcct tgtttgaagc tttgggctac gtggatgacc agctgttcgt gttctatgat      120

catgagagtc gccgtgtgga gccccgaact ccatgggttt ccagtagaat ttcaagccag      180

atgtggctgc agctgagtca gagtctgaaa gggtgggatc acatgttcac tgttgacttc      240

tggactatta tggaaaatca caaccacagc aaggagtccc acaccctgca ggtcatcctg      300

ggctgtgaaa tgcaagaaga caacagtacc gagggctact ggaagtacgg gtatgatggg      360

caggaccacc ttgaattctg ccctgacaca ctggattgga gagcagcaga acccagggcc      420

tggcccacca agctggagtg ggaaaggcac aagattcggg ccaggcagaa cagggcctac      480

ctggagaggg actgccctgc acagctgcag cagttgctgg agctggggag aggtgttttg      540

gaccaacaag tgcctccttt ggtgaaggtg acacatcatg tgacctcttc agtgaccact      600

ctacggtgtc gggccttgaa ctactacccc cagaacatca ccatgaagtg gctgaaggat      660

aagcagccaa tggatgccaa ggagttcgaa cctaaagacg tattgcccaa tggggatggg      720

acctaccagg gctggataac cttggctgta ccccctgggg aagagcagag atatacgtgc      780

caggtggagc acccaggcct ggatcagccc ctcattgtga tctgggagcc ctcaccgtct      840

ggcaccctag tc                                                          852


<210>  3633
<211>  2091
<212>  DNA
<213>  Homo Sapiens

<400>  3633
caaaggaaaa gaagaaatac aattcatgaa ttcaaaaaat cagcaaagac taccctaatc       60

aaaatagatc cagcactgaa gataaaaacc aaaaaagtga atactgcaga ccaatgtgct      120

aatagatgta ctaggaataa aggacttcca ttcacttgca aggcttttgt ttttgataaa      180

gcaagaaaac aatgcctctg gttccccttc aatagcatgt caagtggagt gaaaaaagaa      240

tttggccatg aatttgacct ctatgaaaac aaagactaca ttagaaactg catcattggt      300

aaaggacgca gctacaaggg aacagtatct atcactaaga gtggcatcaa atgtcagccc      360

tggagttcca tgataccaca cgaacacagc tttttgcctt cgagctatcg gggtaaagac      420

ctacaggaaa actactgtcg aaatcctcga ggggaagaag ggggaccctg gtgtttcaca      480

agcaatccag aggtacgcta cgaagtctgt gacattcctc agtgttcaga agttgaatgc      540

atgacctgca atggggagag ttatcgaggt ctcatggatc atacagaatc aggcaagatt      600

tgtcagcgct gggatcatca gacaccacac cggcacaaat tcttgcctga aagatatccc      660

gacaagggct ttgatgataa ttattgccgc aatcccgatg gccagccgag gccatggtgc      720

tatactcttg accctcacac ccgctgggag tactgtgcaa ttaaaacatg cgctgacaat      780

actatgaatg acactgatgt tcctttggaa acaactgaat gcatccaagg tcaaggagaa      840

ggctacaggg gcactgtcaa taccatttgg aatggaattc catgtcagcg ttgggattct      900

cagtatcctc acgagcatga catgactcct gaaaatttca agtgcaagga cctacgagaa      960

aattactgcc gaaatccaga tgggtctgaa tcaccctggt gttttaccac tgatccaaac     1020

atccgagttg gctactgctc ccaaattcca aactgtgata tgtcacatgg acaagattgt     1080

tatcgtggga atggcaaaaa ttatatgggc aacttatccc aaacaagatc tggactaaca     1140

tgttcaatgt gggacaagaa catggaagac ttacatcgtc atatcttctg ggaaccagat     1200

gcaagtaagc tgaatgagaa ttactgccga aatccagatg atgatgctca tggaccctgg     1260

tgctacacgg gaaatccact cattccttgg gattattgcc ctatttctcg ttgtgaaggt     1320

gataccacac ctacaatagt caatttagac catcccgtaa tatcttgtgc caaaacgaaa     1380

caattgcgag ttgtaaatgg gattccaaca cgaacaaaca taggatggat ggttagtttg     1440

agatacagaa ataaacatat ctgcggagga tcattgataa aggagagttg ggttcttact     1500

gcacgacagt gtttcccttc tcgagacttg aaagattatg aagcttggct tggaattcat     1560

gatgtccacg gaagaggaga tgagaaatgc aaacaggttc tcaatgtttc ccagctggta     1620

tatggccctg aaggatcaga tctggtttta atgaagcttg ccaggcctgc tgtcctggat     1680

gattttgtta gtacgattga tttacctaat tatggatgca caattcctga aaagaccagt     1740

tgcagtgttt atggctgggg ctacactgga ttgatcaact atgatggcct attacgagtg     1800

gcacatctct atataatggg aaatgagaaa tgcagccagc atcatcgagg gaaggtgact     1860

ctgaatgagt ctgaaatatg tgctggggct gaaaagattg gatcaggacc atgtgagggg     1920

gattatggtg gcccacttgt ttgtgagcaa cataaaatga gaatggttct tggtgtcatt     1980

gttcctggtc gtggatgtgc cattccaaat cgtcctggta tttttgtccg agtagcatat     2040

tatgcaaaat ggatacacaa aattatttta acatataagg taccacagtc a              2091


<210>  3634
<211>  849
<212>  DNA
<213>  Homo Sapiens

<400>  3634
gtccaactgt caccggatct cctggcgacc ctgcctgagc cagcctcccc ggggcgccag       60

gcctgcggca ggaggcacaa gaagaggacg ttcctgcggc cacgtatcat cggcggctcc      120

tcctcgctgc ccggctcgca cccctggctg gccgccatct acatcgggga cagcttctgc      180

gccgggagcc tggtccacac ctgctgggtg gtgtcggccg cccactgctt ctcccacagc      240

ccccccaggg acagcgtctc cgtggtgctg ggccagcact tcttcaaccg cacgacggac      300

gtgacgcaga ccttcggcat cgagaagtac atcccgtaca ccctgtactc ggtgttcaac      360

cccagcgacc acgacctcgt cctgatccgg ctgaagaaga aaggggaccg ctgtgccaca      420

cgctcgcagt tcgtgcagcc catctgcctg cccgagcccg gcagcacctt ccccgcagga      480

cacaagtgcc agattgcggg ctggggccac ttggatgaga acgtgagcgg ctactccagc      540

tccctgcggg aggccctggt ccccctggtc gccgaccaca agtgcagcag ccctgaggtc      600

tacggcgccg acatcagccc caacatgctc tgtgccggct acttcgactg caagtccgac      660

gcctgccagg gggactcagg ggggcccctg gcctgcgaga agaacggcgt ggcttacctc      720

tacggcatca tcagctgggg tgacggctgc gggcggctcc acaagccggg ggtctacacc      780

cgcgtggcca actatgtgga ctggatcaac gaccggatac ggcctcccag gcggcttgtg      840

gctccctcc                                                              849


<210>  3635
<211>  2049
<212>  DNA
<213>  Homo Sapiens

<400>  3635
ttctttgaag gagatgctaa gtttggggaa agaaacgaag ggagcggagc aaggaggaga       60

aggtgcctga atgggaaccc cccgaagcgc ctgaaaagga gagacaggag gatgatgtcc      120

cagctggagc tgctgagtgg gggagagatg ctgtgcggtg gcttctaccc tcggctgtcc      180

tgctgcctgc ggagtgacag cccggggcta gggcgcctgg agaataagat attttctgtt      240

accaacaaca cagaatgtgg gaagttactg gaggaaatca aatgtgcact ttgctctcca      300

cattctcaaa gcctgttcca ctcacctgag agagaagtct tggaaagaga cctagtactt      360

cctctgctct gcaaagacta ttgcaaagaa ttcttttaca cttgccgagg ccatattcca      420

ggtttccttc aaacaactgc ggatgagttt tgcttttact atgcaagaaa agatggtggg      480

ttgtgctttc cagattttcc aagaaaacaa gtcagaggac cagcatctaa ctacttggac      540

cagatggaag aatatgacaa agtggaagag atcagcagaa agcacaaaca caactgcttc      600

tgtattcagg aggttgtgag tgggctgcgg cagcccgttg gtgccctgca tagtggggat      660

ggctcgcaac gtctcttcat tctggaaaaa gaaggttatg tgaagatact tacccctgaa      720

ggagaaattt tcaaggagcc ttatttggac attcacaaac ttgttcaaag tggaataaag      780

ggaggagatg aaagaggact gctaagcctc gcattccatc ccaattacaa gaaaaatgga      840

aagttgtatg tgtcctatac caccaaccaa gaacggtggg ctatcgggcc tcatgaccac      900

attcttaggg ttgtggaata cacagtatcc agaaaaaatc cacaccaagt tgatttgaga      960

acagccagag tctttcttga agttgcagaa ctccacagaa agcatctggg aggacaactg     1020

ctctttggcc ctgacggctt tttgtacatc attcttggtg atgggatgat tacactggat     1080

gatatggaag aaatggatgg gttaagtgat ttcacaggct cagtgctacg gctggatgtg     1140

gacacagaca tgtgcaacgt gccttattcc ataccaagga gcaacccaca cttcaacagc     1200

accaaccagc cccccgaagt gtttgctcat gggctccacg atccaggcag atgtgctgtg     1260

gatagacatc ccactgatat aaacatcaat ttaacgatac tgtgttcaga ctccaatgga     1320

aaaaacagat catcagccag aattctacag ataataaagg ggaaagatta tgaaagtgag     1380

ccatcacttt tagaattcaa gccattcagt aatggtcctt tggttggtgg atttgtatac     1440

cggggctgcc agtcagaaag attgtatgga agctacgtgt ttggagatcg taatgggaat     1500

ttcctaactc tccagcaaag tcctgtgaca aagcagtggc aagaaaaacc actctgtctc     1560

ggcactagtg ggtcctgtag aggctacttt tccggtcaca tcttgggatt tggagaagat     1620

gaactaggtg aagtttacat tttatcaagc agtaaaagta tgacccagac tcacaatgga     1680

aaactctaca aaattgtaga tcccaaaaga cctttaatgc ctgaggaatg cagagccacg     1740

gtacaacctg cacagacact gacttcagag tgctccaggc tctgtcgaaa cggctactgc     1800

acccccacgg gaaagtgctg ctgcagtcca ggctgggagg gggacttctg cagaactgca     1860

aaatgtgagc cagcatgtcg tcatggaggt gtctgtgtta gaccgaacaa gtgcctctgt     1920

aaaaaaggat atcttggtcc tcaatgtgaa caagtggaca gaaacatccg cagagtgacc     1980

agggcaggta ttcttgatca gatcattgac atgacatctt acttgctgga tctaacaagt     2040

tacattgta                                                             2049


<210>  3636
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  3636
atattccctt tggctttctt catttatgtt cctatgaatg aacaaatcgt cattggaaga       60

cttgatgaag atataattct cccttcttca tttgagaggg gatccgaagt cgtaatacac      120

tggaagtatc aagatagcta taaggttcat agttactaca aaggcagtga ccatttggaa      180

agccaagatc ccagatatgc aaacaggaca tcccttttct ataatgagat tcaaaatggg      240

aatgcgtcac tatttttcag aagagtaagc cttctggacg aaggaattta cacctgctat      300

gtaggaacag caattcaagt gattacaaac aaagtggtgc taaaggtggg agtttttctc      360

acacccgtga tgaagtatga aaagaggaac acaaacagct tcttaatatg cagcgtgtta      420

agtgtttatc ctcgtccaat tatcacgtgg aaaatggaca acacacctat ctctgaaaac      480

aacatggaag aaacagggtc tttggattct ttttctatta acagcccact gaatattaca      540

ggatcaaatt catcttatga atgtacaatt gaaaattcac tgctgaagca aacatggaca      600

gggcgctgga cgatgaaaga tggccttcat aaaatgcaaa gtgaacacgt ttcactctca      660

tgtcaacctg taaatgatta tttttcacca aaccaagact tcaaagttac ttggtccaga      720

atgaaaagtg ggactttctc tgtcctggct tactatctga gctcctcaca aaatacaatt      780

atcaatgaat cccgattctc atggaacaaa gagctgataa accagagtga cttctctatg      840

aatttgatgg atcttaatct ttcagacagt ggggaatatt tatgcaatat ttcttcggat      900

gaatatactt tacttaccat ccacacagtg catgtagaac cgagccaaga aacagcttcc      960

cataac                                                                 966


<210>  3637
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3637
cgtagtcatt ccatgagata tttctatacc accatgagta ggcccggcgc tggcgagcct       60

cgttttataa gcgttggtta tgtagatgat acacaattcg taaggtttga cagtgatgac      120

gcaagcccgc gtgaggaacc gcgtgcgccc tggatggaaa gggagggccc taaatattgg      180

gataggaata cgcaaatatg caaagctcaa gcgcaaactg agcgtgaaaa tcttcgtatc      240

gcattgcgtt actataatca gtctgagggg ggttcccata cgatgcaggt aatgtatggc      300

tgtgacgtgg gcccggatgg gcccttcctt aggggatatg agcaacatgc ctatgatggt      360

aaggactata ttgctttaaa tgaagatttg agatcatgga cagccgcaga tatggctgct      420

caaattacca aaaggaagtg ggaggcggcc agaagggcag aacaacgtag ggtctaccta      480

gaaggcgaat ttgtcgaatg gttgcgtcgt tacctagaaa atggcaaaga aactctgcaa      540

agagctgatc ccccaaagac gcacatgacg caccacccca tcagcgacca cgaagccact      600

ctacgttgct gggcgctagg tttttacccc gccgaaatca cattgacttg gcagagggac      660

ggagaagacc aaacgcagga caccgaattg gtcgagacca ggcccgcagg agatggcaca      720

ttccagaaat gggctgccgt tgtcgtaccg tccggtgagg aacagagata tacctgtcat      780

gtacagcacg agggactgcc cgaacccctg accttgagat gggagccgtc ttcacaacca      840

accgtaccaa ta                                                          852


<210>  3638
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  3638
ggctcccact ccatgaggta tttctacacc gccatgtccc ggcccggccg cggggagccc       60

cgcttcatct cagtgggcta cgtggacgac acgcagttcg tgaggttcga cagcgacgcc      120

gcgagtccga gagaggagcc gcgggcgccg tggatagagc aggaggggcc ggagtattgg      180

gaccggaaca cacagatctg caagaccaac acacagactt accgagagag cctgcggaac      240

ctgcgcggct actacaacca gagcgaggcc gggtctcaca ccctccagag gatgtacggc      300

tgcgacgtgg ggccggacgg gcgcctcctc cgcgggcatg accagtacgc ctacgacggc      360

aaggattaca tcgccctgaa cgaggacctg agctcctgga ccgcggcgga cacggcggct      420

cagatcaccc agcgcaagtg ggaggcggcc cgtgaggcgg agcagctgag agcctacctg      480

gagggcctgt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag      540

cgcgcggacc ccccaaagac acatgtgacc caccacccca tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat      660

ggcgaggacc aaactcagga caccgagctt gtggagacca gaccagcagg agatagaacc      720

ttccagaagt gggcagctgt ggtggtgcct tctggagaag agcagagata cacatgccat      780

gtacagcatg aggggctgcc gaagcccctc accctgagat gggagccatc ttcccagtcc      840

accatcccca tcgtg                                                       855


<210>  3639
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3639
ggctcccact ccatgaggta tttctacacc tccgtgtccc ggcccggccg cggggagccc       60

cgcttcatcg ccgtgggcta cgtggacgac acgcagttcg tgcggttcga cagcgacgcc      120

gcgagccaga ggatggagcc gcgggcgccg tggatagagc aggaggggcc ggagtattgg      180

gaccggaaca cacggaatgt gaaggcccac tcacagactg accgagagag cctgcggatc      240

gcgctccgct actacaacca gagcgaggac ggttctcaca ccatccagag gatgtatggc      300

tgcgacgtgg ggccggacgg gcgcttcctc cgcgggtacc agcaggacgc ttacgacggc      360

aaggattaca tcgccctgaa cgaggacctg cgctcttgga ccgcggcgga catggcggct      420

cagatcaccc agcgcaagtg ggagacggcc catgaggcgg agcagtggag agcctacctg      480

gagggccggt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag      540

cgcacggacg cccccaagac gcatatgact caccacgctg tctctgacca tgaggccacc      600

ctgaggtgct gggccctgag cttctaccct gcggagatca cactgacctg gcagcgggat      660

ggggaggacc agacccagga cacggagctc gtggagacca ggcctgcagg ggatgggacc      720

ttccagaagt gggcgtctgt ggtggtgcct tctggacagg agcagagata cacctgccat      780

gtgcagcatg agggtctgcc caagcccctc accctgagat gggagccgtc ttcccagccc      840

accatcccca tc                                                          852


<210>  3640
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3640
gggtcacata gtatgaggta cttttttaca agtgtcagcc gtcctggaag gggggagccg       60

agatttatag cggtaggcta cgttgacgat acgcaattcg tgagatttga ttcagatgct      120

gcgtcacaga gaatggagcc gagggcaccc tggattgaac aggaaggccc ggaatattgg      180

gatggagaaa ctaggaaagt aaaagcgcat tctcaaacgc acagagtgga cttagggact      240

ctgagggggt attataacca atctgaggcc ggtagccata cagtacaaag aatgtacggg      300

tgtgacgtag ggtccgactg gagattcttg cgtggctacc accagtatgc atacgacggg      360

aaagattaca ttgcattaaa ggaggatctt cgttcctgga cggctgctga catggcggcc      420

caaaccacca agcacaaatg ggaagcagcc catgtcgcag agcagctaag agcatattta      480

gagggcacgt gcgtcgaatg gcttcgtagg tatttagaga atggaaagga gactctacag      540

agaaccgatg cgcccaagac tcacatgaca catcatgccg tgtctgacca cgaggctaca      600

ctaaggtgtt gggcactttc cttttatccg gcggaaatca ccttgacgtg gcaaagagac      660

ggtgaagatc aaacacagga cactgaactt gtagaaacga gacctgcggg tgatggaacg      720

ttccagaaat gggccgctgt agttgtacca tcaggccaag agcaaagata tacttgtcac      780

gtgcagcacg agggacttcc taagccatta accttgaggt gggagccttc tagccagcct      840

actatcccta tt                                                          852


<210>  3641
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3641
ggtagccaca gtatgagata tttttatacg gcgatgtcaa gacctggaag gggggaacca       60

agattcatcg cagtaggata cgtggatgac acccaatttg taagatttga ttcagacgcg      120

gccagtccca gaactgaacc cagggcgccc tggattgagc aagaaggacc agaatattgg      180

gataggaata cccaaatctt caagactaat acgcagactt atagggagtc tctgaggaac      240

ctgaggggtt attataacca aagcgaagcg ggatcacata taatacaaag aatgtacgga      300

tgtgatctag gcccggatgg gaggctgctt agaggtcacg accagagcgc ctacgatggc      360

aaggattata ttgcgcttaa cgaggactta tcaagctgga cggcagcgga cacagccgct      420

cagataacgc agaggaaatg ggaggcggcc agggtcgctg aacagttgag ggcatacttg      480

gagggtctgt gcgtcgaatg gctgagacgt tacttagaaa acgggaaaga aacgcttcag      540

agagctgacc caccgaaaac gcacgttaca catcaccctg taagtgacca cgaagctaca      600

ttgaggtgct gggccttagg tttttatccg gcggagataa ctctgacctg gcagcgtgat      660

ggagaagacc agacccaaga caccgaatta gtcgagacca ggcccgccgg agacaggacc      720

ttccagaaat gggcagcagt tgttgtacca tcaggggagg agcagcgtta cacgtgccat      780

gtccaacatg aaggattgcc aaaaccctta actcttagat gggaaccgag ttcccaatct      840

actatcccaa tt                                                          852


<210>  3642
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3642
ggctcccact ccatgaggta tttcttcaca tccgtgtccc ggcccggccg cggggagccc       60

cgcttcatcg ccgtgggcta cgtggacgac acgcagttcg tgcggttcga cagcgacgcc      120

gcgagccaga agatggagcc gcgggcgccg tggatagagc aggaggggcc ggagtattgg      180

gaccaggaga cacggaatat gaaggcccac tcacagactg accgagcgaa cctggggacc      240

ctgcgcggct actacaacca gagcgaggac ggttctcaca ccatccagat aatgtatggc      300

tgcgacgtgg ggccggacgg gcgcttcctc cgcgggtacc ggcaggacgc ctacgacggc      360

aaggattaca tcgccctgaa cgaggacctg cgctcttgga ccgcggcgga catggcagct      420

cagatcacca agcgcaagtg ggaggcggtc catgcggcgg agcagcggag agtctacctg      480

gagggccggt gcgtggacgg gctccgcaga tacctggaga acgggaagga gacgctgcag      540

cgcacggacc cccccaagac acatatgacc caccacccca tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat      660

ggggaggacc agacccagga cacggagctc gtggagacca ggcctgcagg ggatggaacc      720

ttccagaagt gggcggctgt ggtggtgcct tctggagagg agcagagata cacctgccat      780

gtgcagcatg agggtctgcc caagcccctc accctgagat gggagctgtc ttcccagccc      840

accatcccca tc                                                          852


<210>  3643
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  3643
ggctcccact ccatgaggta tttctacacc gccatgtccc ggcccggccg cggggagccc       60

cgcttcatct cagtgggcta cgtggacgac acgcagttcg tgaggttcga cagcgacgcc      120

gcgagtccga gagaggagcc gcgggcgccg tggatagagc aggaggggcc ggagtattgg      180

gaccggaaca cacagatctg caagaccaac acacagactt accgagagag cctgcggaac      240

ctgcgcggct actacaacca gagcgaggcc gggtctcaca ccctccagag gatgtacggc      300

tgcgacgtgg ggccggacgg gcgcctcctc cgcgggcatg accagtacgc ctacgacggc      360

aaggattaca tcgccctgaa cgaggacctg agctcctgga ccgcggcgga cacggcggct      420

cagatcaccc agcgcaagtg ggaggcggcc cgtgaggcgg agcagctgag agcctacctg      480

gagggcctgt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag      540

cgcgcggacc ccccaaagac acatgtgacc caccacccca tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat      660

ggcgaggacc aaactcagga caccgagctt gtggagacca gaccagcagg agatagaacc      720

ttccagaagt gggcagctgt ggtggtgcct tctggagaag agcagagata cacatgccat      780

gtacagcatg aggggctgcc gaagcccctc accctgagat gggagccatc ttcccagtcc      840

accatcccca tcgtg                                                       855


<210>  3644
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3644
tgctcccact ccatgaggta tttctacacc gccgtgtccc ggcccggccg cggagagccc       60

cgcttcatcg cagtgggcta cgtggacgac acgcagttcg tgcggttcga cagcgacgcc      120

gcgagtccaa gaggggagcc gcgggcgccg tgggtggagc aggaggggcc ggagtattgg      180

gaccgggaga cacagaagta caagcgccag gcacagactg accgagtgag cctgcggaac      240

ctgcgcggct actacaacca gagcgaggcc gggtctcaca ccctccagtg gatgtatggc      300

tgcgacctgg ggcccgacgg gcgcctcctc cgcgggtatg accagtccgc ctacgacggc      360

aaggattaca tcgccctgaa cgaggacctg cgctcctgga ccgccgcgga cacggcggct      420

cagatcaccc agcgcaagtg ggaggcggcc cgtgcggcgg agcagcagag agcctacctg      480

gagggcacgt gcgtggagtg gctccgcaga tacctggaga acgggaagga gacgctgcag      540

cgcgcggaac acccaaagac acacgtgacc caccatctcg tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcgggat      660

ggcgaggacc aaactcagga caccgagctt gtggagacca ggccagcagg agatggaacc      720

ttccagaagt gggcagctgt ggtggtgcct tctggagaag agcagagata cacgtgccat      780

gtgcagcacg aggggctgcc ggagcccctc accctgagat gggagccatc ttcccagccc      840

accatcccca tc                                                          852


<210>  3645
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3645
gtccctgaag ctcctactcc aatgtggcca gatgacctgc aaaaccacac attcctgcac       60

acagtgtact gccaggatgg gagtcccagt gtgggactct ctgaggccta cgacgaggac      120

cagcttttct tcttcgactt ttcccagaac actcgggtgc ctcgcctgcc cgaatttgct      180

gactgggctc aggaacaggg agatgctcct gccattttat ttgacaaaga gttctgcgag      240

tggatgatcc agcaaatagg gccaaaactt gatgggaaaa tcccggtgtc cagagggttt      300

cctatcgctg aagtgttcac gctgaagccc ctggagtttg gcaagcccaa cactttggtc      360

tgttttgtca gtaatctctt cccacccatg ctgacagtga actggcagca tcattccgtc      420

cctgtggaag gatttgggcc tacttttgtc tcagctgtcg atggactcag cttccaggcc      480

ttttcttact taaacttcac accagaacct tctgacattt tctcctgcat tgtgactcac      540

gaaattgacc gctacacagc aattgcctat tgggtacccc ggaacgcact gccctcagat      600

ctgctggaga atgtgctgtg t                                                621


<210>  3646
<211>  600
<212>  DNA
<213>  Homo Sapiens

<400>  3646
ggtggcttcg tggcccatgt ggaaagcacc tgtctgttgg atgatgctgg gactccaaag       60

gatttcacat actgcatctc cttcaacaag gatctgctga cctgctggga tccagaggag      120

aataagatgg ccccttgcga atttggggtg ctgaatagct tggcgaatgt cctctcacag      180

cacctcaacc aaaaagacac cctgatgcag cgcttgcgca atgggcttca gaattgtgcc      240

acacacaccc agcccttctg gggatcactg accaacagga cacggccacc atctgtgcaa      300

gtagccaaaa ccactccttt taacacgagg gagcctgtga tgctggcctg ctatgtgtgg      360

ggcttctatc cagcagaagt gactatcacg tggaggaaga acgggaagct tgtcatgcct      420

cacagcagtg cgcacaagac tgcccagccc aatggagact ggacatacca gaccctctcc      480

catttagcct taaccccctc ttacggggac acttacacct gtgtggtaga gcacattggg      540

gctcctgagc ccatccttcg ggactggaca cctgggctgt cccccatgca gaccctgaag      600


<210>  3647
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  3647
accaaggctg accacatggg ctcctacgga cccgccttct accagtctta cggcgcctcg       60

ggccagttca cccatgaatt tgatgaggaa cagctgttct ctgtggacct gaagaaaagc      120

gaggccgtgt ggcgtctgcc tgagtttggc gactttgccc gctttgaccc gcagggcggg      180

ctggccggca tcgccgcaat caaagcccat ctggacatcc tggtggagcg ctccaaccgc      240

agcagagcca tcaacgtgcc tccacgggtg accgtgctcc ccaaatctcg ggtggagctg      300

ggccagccca acatcctcat ctgcatcgtg gacaacatct tcccccctgt gatcaatatc      360

acctggctgc gcaacggcca aactgtcact gagggagtgg cccagaccag cttctattcc      420

cagcctgacc atttgttccg caagttccac tacctgccct tcgtgccctc agccgaggac      480

gtctatgact gccaggtgga gcactggggc ctggatgcgc cactcctcag gcattgggag      540

ctccaggtgc ctattccacc accagatgcc atggag                                576


<210>  3648
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  3648
acagactctc cagaagattt tgtgattcag gcaaaggctg actgttactt caccaacggg       60

acagaaaagg tgcagtttgt ggtcagattc atctttaact tggaggagta tgtacgtttc      120

gacagtgatg tggggatgtt tgtggcattg accaagctgg ggcagccaga tgctgagcag      180

tggaacagcc ggctggatct cttggagagg agcagacagg ccgtggatgg ggtctgtaga      240

cacaactaca ggctgggcgc acccttcact gtggggagaa aagtgcaacc agaggtgaca      300

gtgtacccag agaggacccc actcctgcac cagcataatc tgctgcactg ctctgtgaca      360

ggcttctatc caggggatat caagatcaag tggttcctga atgggcagga ggagagagct      420

ggggtcatgt ccactggccc tatcaggaat ggagactgga cctttcagac tgtggtgatg      480

ctagaaatga ctcctgaact tggacatgtc tacacctgcc ttgtcgatca ctccagcctg      540

ctgagccctg tttctgtgga gtggagagct cagtctgaat attcttggag aaag            594


<210>  3649
<211>  582
<212>  DNA
<213>  Homo Sapiens

<400>  3649
gctggggcca tcaaggcgga ccatgtgtca acttatgccg cgtttgtaca gacccataga       60

ccaacagggg agtttatgtt tgaatttgat gaagatgagc agttctatgt ggatctggat      120

aaaaaggaga ccgtctggca tctggaggag tttggccgag ccttttcctt tgaggctcag      180

ggcgggctgg ctaacattgc tatattgaac aacaacttga ataccttgat ccagcgttcc      240

aaccacactc aggccgccaa tgatccccct gaggtgaccg tgtttcccaa ggagcctgtg      300

gagctgggcc agcccaacac cctcatctgc cacattgaca ggttcttccc accagtgctc      360

aacgtcacat ggctgtgcaa tggggagcca gtcactgagg gtgtcgctga gagcctcttc      420

ctgcccagaa cagattacag cttccacaag ttccattacc tgacctttgt gccctcagca      480

gaggacgtct atgactgcag ggtggagcac tggggcttgg accagccgct cctcaagcac      540

tgggaggccc aagagccaat ccagatgcct gagacaacgg ag                         582


<210>  3650
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  3650
agggccactc cagagaatta ccttttccag ggacggcagg aatgctacgc gtttaatggg       60

acacagcgct tcctggagag atacatctac aaccgggagg agttcgtgcg cttcgacagc      120

gacgtggggg agttccgggc ggtgacggag ctggggcggc ctgctgcgga gtactggaac      180

agccagaagg acatcctgga ggagaagcgg gcagtgccgg acaggatgtg cagacacaac      240

tacgagctgg gcgggcccat gaccctgcag cgccgagtcc agcctagggt gaatgtttcc      300

ccctccaaga aggggccctt gcagcaccac aacctgcttg tctgccacgt gacggatttc      360

tacccaggca gcattcaagt ccgatggttc ctgaatggac aggaggaaac agctggggtc      420

gtgtccacca acctgatccg taatggagac tggaccttcc agatcctggt gatgctggaa      480

atgacccccc agcagggaga tgtctacacc tgccaagtgg agcacaccag cctggatagt      540

cctgtcaccg tggagtggaa ggcacagtct gattctgccc ggagtaag                   588


<210>  3651
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  3651
gaagacattg tggctgacca cgtcgcctct tatggtgtaa acttgtacca gtcttacggt       60

ccctctggcc agtacaccca tgaatttgat ggagatgagc agttctacgt ggacctgggg      120

aggaaggaga ctgtctggtg tttgcctgtt ctcagacaat ttagatttga cccgcaattt      180

gcactgacaa acatcgctgt cctaaaacat aacttgaaca tcctgattaa acgctccaac      240

tctactgctg ctaccaatga ggttcctgag gtcacagtgt tttccaagtc tcccgtgacg      300

ctgggtcagc ccaacaccct catctgtctt gtggacaaca tctttcctcc tgtggtcaac      360

atcacatggc tgagcaatgg gcactcagtc acagaaggtg tttctgagac cagcttcctc      420

tccaagagtg atcattcctt cttcaagatc agttacctca ccttcctccc ttctgctgat      480

gagatttatg actgcaaggt ggagcactgg ggcctggacg agcctcttct gaaacactgg      540

gagcctgaga ttccagcccc tatgtcagag ctcacagag                             579


<210>  3652
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  3652
agagactctc ccgaggattt cgtgtaccag tttaagggca tgtgctactt caccaacggg       60

acggagcgcg tgcgtcttgt gaccagatac atctataacc gagaggagta cgcacgcttc      120

gacagcgacg tgggggtgta tcgggcggtg acgccgctgg ggccgcctgc cgccgagtac      180

tggaacagcc agaaggaagt cctggagagg acccgggcgg agttggacac ggtgtgcaga      240

cacaactacc agttggagct ccgcacgacc ttgcagcggc gagtggagcc cacagtgacc      300

atctccccat ccaggacaga ggccctcaac caccacaacc tgctggtctg ctcagtgaca      360

gatttctatc cagcccagat caaagtccgg tggtttcgga atgaccagga ggagacaact      420

ggcgttgtgt ccacccccct tattaggaac ggtgactgga ccttccagat cctggtgatg      480

ctggaaatga ctccccagcg tggagacgtc tacacctgcc acgtggagca ccccagcctc      540

cagaacccca tcatcgtgga gtggcgggct cagtctgaat ctgcccagag caag            594


<210>  3653
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  3653
atcaaagaag aacatgtgat catccaggcc gagttctatc tgaatcctga ccaatcaggc       60

gagtttatgt ttgactttga tggtgatgag attttccatg tggatatggc aaagaaggag      120

acggtctggc ggcttgaaga atttggacga tttgccagct ttgaggctca aggtgcattg      180

gccaacatag ctgtggacaa agccaacctg gaaatcatga caaagcgctc caactatact      240

ccgatcacca atgtacctcc agaggtaact gtgctcacga acagccctgt ggaactgaga      300

gagcccaacg tcctcatctg tttcatagac aagttcaccc caccagtggt caatgtcacg      360

tggcttcgaa atggaaaacc tgtcaccaca ggagtgtcag agacagtctt cctgcccagg      420

gaagaccacc ttttccgcaa gttccactat ctccccttcc tgccctcaac tgaggacgtt      480

tacgactgca gggtggagca ctggggcttg gatgagcctc ttctcaagca ctgggagttt      540

gatgctccaa gccctctccc agagactaca gag                                   573


<210>  3654
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  3654
ggggacaccc gaccacgttt cctgtggcag cctaagaggg agtgtcattt cttcaatggg       60

acggagcggg tgcggttcct ggacagatac ttctataacc aggaggagtc cgtgcgcttc      120

gacagcgacg tgggggagtt ccgggcggtg acggagctgg ggcggcctga cgctgagtac      180

tggaacagcc agaaggacat cctggagcag gcgcgggccg cggtggacac ctactgcaga      240

cacaactacg gggttggtga gagcttcgca gtgcagcggc gagtccaacc taaggtgact      300

gtatatcctt caaagaccca gcccctgcag caccacaacc tcctggtctg ctctgtgagt      360

ggtttctatc caggcagcat tgaagtcagg tggttcctga acggccagga agagaaggct      420

gggatggtgt ccacaggcct gatccagaat ggagactgga ccttccagac cctggtgatg      480

ctggaaacag ttcctcgaag tggagaggtt tacacctgcc aagtggagca cccaagcgtg      540

acaagccctc tcacagtgga atggagagca cggtctgaat ctgcacagag caag            594


<210>  3655
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3655
ggctcccact ccttgaagta tttccacact tccgtgtccc ggcccggccg cggggagccc       60

cgcttcatct ctgtgggcta cgtggacgac acccagttcg tgcgcttcga caacgacgcc      120

gcgagtccga ggatggtgcc gcgggcgccg tggatggagc aggaggggtc agagtattgg      180

gaccgggaga cacggagcgc cagggacacc gcacagattt tccgagtgaa cctgcggacg      240

ctgcgcggct actacaatca gagcgaggcc gggtctcaca ccctgcagtg gatgcatggc      300

tgcgagctgg ggcccgacag gcgcttcctc cgcgggtatg aacagttcgc ctacgacggc      360

aaggattatc tcaccctgaa tgaggacctg cgctcctgga ccgcggtgga cacggcggct      420

cagatctccg agcaaaagtc aaatgatgcc tctgaggcgg agcaccagag agcctacctg      480

gaagacacat gcgtggagtg gctccacaaa tacctggaga aggggaagga gacgctgctt      540

cacctggagc ccccaaagac acacgtgact caccacccca tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cactgacctg gcagcaggat      660

ggggagggcc atacccagga cacggagctc gtggagacca ggcctgcagg ggatggaacc      720

ttccagaagt gggcagctgt ggtggtgcct tctggagagg agcagagata cacgtgccat      780

gtgcagcatg aggggctacc cgagcccgtc accctgagat ggaagccggc ttcccagccc      840

accatcccca tc                                                          852


<210>  3656
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3656
ggctcccact ccttgaggta tttcagcacc gctgtgtcgc ggcccggccg cggggagccc       60

cgctacatcg ccgtggagta cgtagacgac acgcaattcc tgcggttcga cagcgacgcc      120

gcgattccga ggatggagcc gcgggagccg tgggtggagc aagaggggcc gcagtattgg      180

gagtggacca cagggtacgc caaggccaac gcacagactg accgagtggc cctgaggaac      240

ctgctccgcc gctacaacca gagcgaggct gggtctcaca ccctccaggg aatgaatggc      300

tgcgacatgg ggcccgacgg acgcctcctc cgcgggtatc accagcacgc gtacgacggc      360

aaggattaca tctccctgaa cgaggacctg cgctcctgga ccgcggcgga caccgtggct      420

cagatcaccc agcgcttcta tgaggcagag gaatatgcag aggagttcag gacctacctg      480

gagggcgagt gcctggagtt gctccgcaga tacttggaga atgggaagga gacgctacag      540

cgcgcagatc ctccaaaggc acacgttgcc caccacccca tctctgacca tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca cgctgacctg gcagcgggat      660

ggggaggaac agacccagga cacagagctt gtggagacca ggcctgcagg ggatggaacc      720

ttccagaagt gggccgctgt ggtggtgcct tctggagagg aacagagata cacatgccat      780

gtgcagcacg aggggctgcc ccagcccctc atcctgagat gggagcagtc tccccagccc      840

accatcccca tc                                                          852


<210>  3657
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  3657
ggctcccact ccatgaggta tttcagcgcc gccgtgtccc ggcccagccg cggggagccc       60

cgcttcatcg ccatgggcta cgtggacgac acgcagttcg tgcggttcga cagcgactcg      120

gcgtgtccga ggatggagcc gcgggcgccg tgggtggagc gggaggggcc agagtattgg      180

gaagaggaga cacggaacac caaggcccac gcacagactg acagaatgaa cctgcagacc      240

ctgcgcggct actacaacca gagcgaggcc agttctcata ccctccagtg gatgattggc      300

tgcgacctgg ggtccgacgg acgcctcctc cgcgggtatg aacagtatgc ctacgatggc      360

aaggattacc tcgccctgaa cgaggacctg cgctcctgga ccgcagcgga cactgcggct      420

cagatctcca agcgcaagtg tgaggcggcc aatgtggctg aacaaaggag agcctacctg      480

gagggcacgt gcgtggagtg gctccacaga tacctggaga acgggaagga gatgctgcag      540

cgcgcggacc cccccaagac acacgtgacc caccaccctg tctttgacta tgaggccacc      600

ctgaggtgct gggccctggg cttctaccct gcggagatca tactgacctg gcagcgggat      660

ggggaggacc agacccagga cgtggagctc gtggagacca agcctgcagg ggatggaacc      720

ttccagaagt gggcagctgt ggtggtgcct tctggagagg agcagagata cacgtgccat      780

gtgcagcatg aggggctgcc ggagcccctc atgctgagat ggaagcagtc ttccctgccc      840

accatcccca tc                                                          852


<210>  3658
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  3658
ggcaaaggag atcctaagaa gccgagaggc aaaatgtcat catatgcatt ttttgtgcaa       60

acttgtcggg aggagcataa gaagaagcac ccagatgctt cagtcaactt ctcagagttt      120

tctaagaagt gctcagagag gtggaagacc atgtctgcta aagagaaagg aaaatttgaa      180

gatatggcaa aggcggacaa ggcccgttat gaaagagaaa tgaaaaccta tatccctccc      240

aaaggggaga caaaaaagaa gttcaaggat cccaatgcac ccaagaggcc tccttcggcc      300

ttcttcctct tctgctctga gtatcgccca aaaatcaaag gagaacatcc tggcctgtcc      360

attggtgatg ttgcgaagaa actgggagag atgtggaata acactgctgc agatgacaag      420

cagccttatg aaaagaaggc tgcgaagctg aaggaaaaat acgaaaagga tattgctgca      480

tatcgagcta aaggaaagcc tgatgcagca aaaaagggag ttgtcaaggc tgaaaaaagc      540

aagaaaaaga aggaagagga ggaagatgag gaagatgaag aggatgagga ggaggaggaa      600

gatgaagaag atgaagatga agaagaagat gatgatgatg aa                         642


<210>  3659
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  3659
ggtaaaggag accccaacaa gccgcggggc aaaatgtcct cgtacgcctt cttcgtgcag       60

acctgccggg aagagcacaa gaagaaacac ccggactctt ccgtcaattt cgcggaattc      120

tccaagaagt gttcggagag atggaagacc atgtctgcaa aggagaagtc gaagtttgaa      180

gatatggcaa aaagtgacaa agctcgctat gacagggaga tgaaaaatta cgttcctccc      240

aaaggtgata agaaggggaa gaaaaaggac cccaatgctc ctaaaaggcc accatctgcc      300

ttcttcctgt tttgctctga acatcgccca aagatcaaaa gtgaacaccc tggcctatcc      360

attggggata ctgcaaagaa attgggtgaa atgtggtctg agcagtcagc caaagataaa      420

caaccatatg aacagaaagc agctaagcta aaggagaaat atgaaaagga tattgctgca      480

tatcgtgcca agggcaaaag tgaagcagga aagaagggcc ctggcaggcc aacaggctca      540

aagaagaaga acgaaccaga agatgaggag gaggaggagg aagaagaaga tgaagatgag      600

gaggaagagg atgaagatga agaa                                             624


<210>  3660
<211>  1242
<212>  DNA
<213>  Homo Sapiens

<400>  3660
tttaggggcc ccttgctacc caaccggccc ttcaccaccg tctggaatgc aaacacccag       60

tggtgcctgg agaggcacgg tgtggacgtg gatgtcagtg tcttcgatgt ggtagccaac      120

ccagggcaga ccttccgcgg ccctgacatg acaattttct atagctccca gctgggcacc      180

tacccctact acacgcccac tggggagcct gtgtttggtg gtctgcccca gaatgccagc      240

ctgattgccc acctggcccg cacattccag gacatcctgg ctgccatacc tgctcctgac      300

ttctcagggc tggcagtcat cgactgggag gcatggcgcc cacgctgggc cttcaactgg      360

gacaccaagg acatttaccg gcagcgctca cgggcactgg tacaggcaca gcaccctgat      420

tggccagctc ctcaggtgga ggcagtagcc caggaccagt tccagggagc tgcacgggcc      480

tggatggcag gcaccctcca gctggggcgg gcactgcgtc ctcgcggcct ctggggcttc      540

tatggcttcc ctgactgcta caactatgac tttctaagcc ccaactacac cggccagtgc      600

ccatcaggca tccgtgccca aaatgaccag ctagggtggc tgtggggcca gagccgtgcc      660

ctctatccca gcatctacat gcccgcagtg ctggagggca cagggaagtc acagatgtat      720

gtgcaacacc gtgtggccga ggcattccgt gtggctgtgg ctgctggtga ccccaatctg      780

ccggtgctgc cctatgtcca gatcttctat gacacgacaa accactttct gcccctggat      840

gagctggagc acagcctggg ggagagtgcg gcccaggggg cagctggagt ggtgctctgg      900

gtgagctggg aaaatacaag aaccaaggaa tcatgtcagg ccatcaagga gtatatggac      960

actacactgg ggcccttcat cctgaacgtg accagtgggg cccttctctg cagtcaagcc     1020

ctgtgctccg gccatggccg ctgtgtccgc cgcaccagcc accccaaagc cctcctcctc     1080

cttaaccctg ccagtttctc catccagctc acgcctggtg gtgggcccct gagcctgcgg     1140

ggtgccctct cacttgaaga tcaggcacag atggctgtgg agttcaaatg tcgatgctac     1200

cctggctggc aggcaccgtg gtgtgagcgg aagagcatgt gg                        1242


<210>  3661
<211>  1284
<212>  DNA
<213>  Homo Sapiens

<400>  3661
atggagctca agcccacagc accacccatc ttcactggcc ggccctttgt ggtagcgtgg       60

gacgtgccca cacaggactg tggcccacgc ctcaaggtgc cactggacct gaatgccttt      120

gatgtgcagg cctcacctaa tgagggtttt gtgaaccaga atattaccat cttctaccgc      180

gaccgtctag gcctgtatcc acgcttcgat tctgccggaa ggtctgtgca tggtggtgtg      240

ccacagaatg tcagcctttg ggcacaccgg aagatgctgc agaaacgtgt ggagcactac      300

attcggacac aggagtctgc ggggctggcg gtcatcgact gggaggactg gcgacctgtg      360

tgggtgcgca actggcagga caaagatgtg tatcgccggt tatcacgcca gctagtggcc      420

agtcgtcacc ctgactggcc tccagaccgc atagtcaaac aggcacaata tgagtttgag      480

ttcgcagcac agcagttcat gctggagaca ctgcgttatg tcaaggcagt gcggccccgg      540

cacctctggg gcttctacct ctttcctgac tgctacaatc atgattatgt gcagaactgg      600

gagagctaca caggccgctg ccctgatgtt gaggtggccc gcaatgacca gctggcctgg      660

ctgtgggctg agagcacggc cctcttcccg tctgtctacc tggacgagac acttgcttcc      720

tcccgccatg gccgcaactt tgtgagcttc cgtgttcagg aggcccttcg tgtggctcgc      780

acccaccatg ccaaccatgc actcccagtc tacgtcttca cacgacccac ctacagccgc      840

aggctcacgg ggcttagtga gatggacctc atctctacca ttggcgagag tgcggccctg      900

ggcgcagctg gtgtcatcct ctggggtgac gcggggtaca ccacaagcac ggagacctgc      960

cagtacctca aagattacct gacacggctg ctggtcccct acgtggtcaa tgtgtcctgg     1020

gccacccaat attgcagccg ggcccagtgc catggccatg ggcgctgtgt gcgccgcaac     1080

cccagtgcca gtaccttcct gcatctcagc accaacagtt tccgcctagt gcctggccat     1140

gcacctggtg aaccccagct gcgacctgtg ggggagctca gttgggccga cattgaccac     1200

ctgcagacac acttccgctg ccagtgctac ttgggctgga gtggtgagca atgccagtgg     1260

gaccataggc aggcagctgg aggt                                            1284


<210>  3662
<211>  1191
<212>  DNA
<213>  Homo Sapiens

<400>  3662
cagcccctac cacaggtccc tgaacgcccc ttctctgtgc tgtggaatgt accctcagca       60

cactgtgagg cccgctttgg tgtgcacctg ccactcaatt ctctgggcat catagccaac      120

cgtggccagc attttcacgg tcagaacatg accattttct acaagaacca actcggcctc      180

tatccctact ttggacccag gggcacagct cacaatgggg gcatccccca ggctttgccc      240

cttgaccgcc acctggcact ggctgcctac cagatccacc acagcctgag acctggcttt      300

gctggcccag cagtgctgga ttgggaggag tggtgtccac tctgggctgg gaactggggc      360

cgccgccgag cttatcaggc agcctcttgg gcttgggcac agcaggtatt ccctgacctg      420

gaccctcagg agcagctcta caaggcctat actggctttg agcaggcggc ccgtgcactg      480

atggaggata cgctgcgggt ggcccaggca ctacggcccc atggactctg gggcttctat      540

cactacccag cctgtggcaa tggctggcat agtatggctt ccaactatac cggccgctgc      600

catgcagcca cccttgcccg caacactcaa ctgcattggc tctgggccgc ctccagtgcc      660

ctcttcccca gcatctacct cccacccagg ctgccacctg cccaccacca ggcctttgtc      720

cgacatcgcc tggaggaggc cttccgtgtg gcccttgttg ggcaccgaca tcccctgcct      780

gtcctggcct atgtccgcct cacacaccgg agatctggga ggttcctgtc ccaggatgac      840

cttgtgcagt ccattggtgt gagtgcagca ctaggggcag ccggcgtggt gctctggggg      900

gacctgagcc tctccagctc tgaggaggag tgctggcatc tccatgacta cctggtggac      960

accttgggcc cctatgtgat caatgtgacc agggcagcga tggcctgcag tcaccagcgg     1020

tgccatggcc acgggcgctg tgcccggcga gatccaggac agatggaagc ctttctacac     1080

ctgtggccag acggcagcct tggagattgg aagtccttca gctgccactg ttactggggc     1140

tgggctggcc ccacctgcca ggagcccagg cctgggccta aagaagcagt a              1191


<210>  3663
<211>  1359
<212>  DNA
<213>  Homo Sapiens

<400>  3663
cagacatctg tgtccccctc aaaagtcatc ctgccccggg gaggctccgt gctggtgaca       60

tgcagcacct cctgtgacca gcccaagttg ttgggcatag agaccccgtt gcctaaaaag      120

gagttgctcc tgcctgggaa caaccggaag gtgtatgaac tgagcaatgt gcaagaagat      180

agccaaccaa tgtgctattc aaactgccct gatgggcagt caacagctaa aaccttcctc      240

accgtgtact ggactccaga acgggtggaa ctggcacccc tcccctcttg gcagccagtg      300

ggcaagaacc ttaccctacg ctgccaggtg gagggtgggg caccccgggc caacctcacc      360

gtggtgctgc tccgtgggga gaaggagctg aaacgggagc cagctgtggg ggagcccgct      420

gaggtcacga ccacggtgct ggtgaggaga gatcaccatg gagccaattt ctcgtgccgc      480

actgaactgg acctgcggcc ccaagggctg gagctgtttg agaacacctc ggccccctac      540

cagctccaga cctttgtcct gccagcgact cccccacaac ttgtcagccc ccgggtccta      600

gaggtggaca cgcaggggac cgtggtctgt tccctggacg ggctgttccc agtctcggag      660

gcccaggtcc acctggcact gggggaccag aggttgaacc ccacagtcac ctatggcaac      720

gactccttct cggccaaggc ctcagtcagt gtgaccgcag aggacgaggg cacccagcgg      780

ctgacgtgtg cagtaatact ggggaaccag agccaggaga cactgcagac agtgaccatc      840

tacagctttc cggcgcccaa cgtgattctg acgaagccag aggtctcaga agggaccgag      900

gtgacagtga agtgtgaggc ccaccctaga gccaaggtga cgctgaatgg ggttccagcc      960

cagccactgg gcccgagggc ccagctcctg ctgaaggcca ccccagagga caacgggcgc     1020

agcttctcct gctctgcaac cctggaggtg gccggccagc ttatacacaa gaaccagacc     1080

cgggagcttc gtgtcctgta tggcccccga ctggacgaga gggattgtcc gggaaactgg     1140

acgtggccag aaaattccca gcagactcca atgtgccagg cttgggggaa cccattgccc     1200

gagctcaagt gtctaaagga tggcactttc ccactgccca tcggggaatc agtgactgtc     1260

actcgagatc ttgagggcac ctacctctgt cgggccagga gcactcaagg ggaggtcacc     1320

cgcaaggtga ccgtgaatgt gctctccccc cggtatgag                            1359


<210>  3664
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  3664
aaggtattcg aggtacacgt gaggccaaag aagctggcgg ttgagcccaa agggtccctc       60

gaggtcaact gcagcaccac ctgtaaccag cctgaagtgg gtggtctgga gacctctcta      120

gataagattc tgctggacga acaggctcag tggaaacatt acttggtctc aaacatctcc      180

catgacacgg tcctccaatg ccacttcacc tgctccggga agcaggagtc aatgaattcc      240

aacgtcagcg tgtaccagcc tccaaggcag gtcatcctga cactgcaacc cactttggtg      300

gctgtgggca agtccttcac cattgagtgc agggtgccca ccgtggagcc cctggacagc      360

ctcaccctct tcctgttccg tggcaatgag actctgcact atgagacctt cgggaaggca      420

gcccctgctc cgcaggaggc cacagccaca ttcaacagca cggctgacag agaggatggc      480

caccgcaact tctcctgcct ggctgtgctg gacttgatgt ctcgcggtgg caacatcttt      540

cacaaacact cagccccgaa gatgttggag atctatgagc ctgtgtcgga cagccag         597


<210>  3665
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  3665
caggagttcc ttttgcgggt ggagccccag aaccctgtgc tctctgctgg agggtccctg       60

tttgtgaact gcagtactga ttgtcccagc tctgagaaaa tcgccttgga gacgtcccta      120

tcaaaggagc tggtggccag tggcatgggc tgggcagcct tcaatctcag caacgtgact      180

ggcaacagtc ggatcctctg ctcagtgtac tgcaatggct cccagataac aggctcctct      240

aacatcaccg tgtacaggct cccggagcgt gtggagctgg cacccctgcc tccttggcag      300

ccggtgggcc agaacttcac cctgcgctgc caagtggagg atgggtcgcc ccggaccagc      360

ctcacggtgg tgctgcttcg ctgggaggag gagctgagcc ggcagcccgc agtggaggag      420

ccagcggagg tcactgccac tgtgctggcc agcagagacg accacggagc ccctttctca      480

tgccgcacag aactggacat gcagccccag gggctgggac tgttcgtgaa cacctcagcc      540

ccccgccagc tccgaacctt tgtcctgccc gtgacccccc cgcgcctcgt ggccccccgg      600

ttcttggagg tggaaacgtc gtggccggtg gactgcaccc tagacgggct ttttccagcc      660

tcagaggccc aggtctacct ggcgctgggg gaccagatgc tgaatgcgac agtcatgaac      720

cacggggaca cgctaacggc cacagccaca gccacggcgc gcgcggatca ggagggtgcc      780

cgggagatcg tctgcaacgt gaccctaggg ggcgagagac gggaggcccg ggagaacttg      840

acggtcttta gcttcctagg acccattgtg aacctcagcg agcccaccgc ccatgagggg      900

tccacagtga ccgtgagttg catggctggg gctcgagtcc aggtcacgct ggacggagtt      960

ccggccgcgg ccccggggca gccagctcaa cttcagctaa atgctaccga gagtgacgac     1020

ggacgcagct tcttctgcag tgccactctc gaggtggacg gcgagttctt gcacaggaac     1080

agtagcgtcc agctgcgagt cctgtatggt cccaaaattg accgagccac atgcccccag     1140

cacttgaaat ggaaagataa aacgagacac gtcctgcagt gccaagccag gggcaacccg     1200

taccccgagc tgcggtgttt gaaggaaggc tccagccggg aggtgccggt ggggatcccg     1260

ttcttcgtca acgtaacaca taatggtact tatcagtgcc aagcgtccag ctcacgaggc     1320

aaatacaccc tggtcgtggt gatggacatt gaggctggga gctcccac                  1368


<210>  3666
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  3666
gcgctgggac gccggactaa gcgggcgcaa agccccaagg gtagccctct cgcgccctcc       60

gggacctcag tgcccttctg ggtgcgcatg agcccggagt tcgtggctgt gcagccgggg      120

aagtcagtgc agctcaattg cagcaacagc tgtccccagc cgcagaattc cagcctccgc      180

accccgctgc ggcaaggcaa gacgctcaga gggccgggtt gggtgtctta ccagctgctc      240

gacgtgaggg cctggagctc cctcgcgcac tgcctcgtga cctgcgcagg aaaaacacgc      300

tgggccacct ccaggatcac cgcctacagt gttcccggtg ggctacttgg tggtgaccct      360

gaggcatgga agccgggtca tctattccga aagcctggag cgcttcaccg gcctggatct      420

ggccaacgtg accttgacct acgagtttgc tgctggaccc cgcgacttct ggcagcccgt      480

gatctgccac gcgcgcctca atctcgacgg cctggtggtc cgcaacagct cggcacccat      540

tacactgatg ctcgcttgga gccccgcgcc cacagctttg gcctccggtt ccatcgctgc      600

ccttgtaggg atcctcctca ctgtgggcgc tgcgtaccta tgcaagtgcc tagctatgaa      660

gtcccaggcg taaaggggga tgttctatgc cggctgagcg agaaaaagag gaatatgaaa      720

caatctgggg aaatggccat acatggtggc                                       750


<210>  3667
<211>  2412
<212>  DNA
<213>  Homo Sapiens

<400>  3667
gagcccttct gggcggacct gcagcctcgc gtggcgttcg tggagcgcgg gggctcgctg       60

tggctgaatt gcagcaccaa ctgccctcgg ccggagcgcg gtggcctgga gacctcgctg      120

cgccgaaacg ggacccagag gggtttgcgt tggttggcgc ggcagctggt ggacattcgc      180

gagccggaga ctcagcccgt ctgcttcttc cgctgcgcgc ggcgcacact acaggcgcgt      240

gggctcattc gcactttcca gcgaccagat cgcgtagagc tgatgccgct gcctccctgg      300

cagccggtgg gcgagaactt caccctgagc tgtagggtcc ccggcgccgg gccccgtgcg      360

agcctcacgc tgaccctgct gcggggcgcc caggagctga tccgccgcag cttcgccggt      420

gaaccacccc gagcgcgggg cgcggtgctc acagccacgg tactggctcg gagggaggac      480

catggagcca atttctcgtg tcgcgccgag ctggacctgc ggccgcacgg actgggactg      540

tttgaaaaca gctcggcccc cagagagctc cgaaccttct ccctgtctcc ggatgccccg      600

cgcctcgctg ctccccggct cttggaagtt ggctcggaaa ggcccgtgag ctgcactctg      660

gacggactgt ttccagcctc agaggccagg gtctacctcg cactggggga ccagaatctg      720

agtcctgatg tcaccctcga aggggacgca ttcgtggcca ctgccacagc cacagctagc      780

gcagagcagg agggtgccag gcagctgatc tgcaacgtca ccctgggggg cgaaaaccgg      840

gagacccggg agaacgtgac catctacagc ttcccggcac cactcctgac cctgagcgaa      900

cccagcgtct ccgaggggca gatggtgaca gtaacctgcg cagctgggac ccaagctctg      960

gtcacactgg agggagttcc agccgcggtc ccggggcagc ccgcccagct tcagctaaat     1020

gccaccgaga acgacgacag acgcagcttc ttctgcgacg ccaccctcga tgtggacggg     1080

gagaccctga tcaagaacag gagcgcagag cttcgtgtcc tatacgctcc ccggctagac     1140

gattcggact gccccaggag ttggacgtgg cccgagggcc cagagcagac gctgcgctgc     1200

gaggcccgcg ggaacccaga accctcagtg cactgtgcgc gctccgacgg cggggccgtg     1260

ctggctctgg gcctgctggg tccagtcact cgggcgctct caggcactta ccgctgcaag     1320

gcggccaatg atcaaggcga ggcggtcaag gacgtaacgc taacggtgga gtacgcacca     1380

gcgctggaca gcgtgggctg cccagaacgc attacttggc tggagggaac agaagcctcg     1440

ctgagctgtg tggcgcacgg ggtaccgccg cctgatgtga tctgcgtgcg ctctggagaa     1500

ctcggggccg tcatcgaagg gctgttgcgt gtggcccggg agcatgcggg cacttaccgc     1560

tgcgaagcca ccaaccctcg gggctctgcg gccaaaaatg tggccgtcac ggtggaatat     1620

ggccccaggt ttgaggagcc gagctgcccc agcaattgga catgggtgga aggatctggg     1680

cgcctgtttt cctgtgaggt cgatgggaag ccacagccaa gcgtgaagtg cgtgggctcc     1740

gggggcgcca ctgagggggt gctgctgccg ctggcacccc cagaccctag tcccagagct     1800

cccagaatcc ctagagtcct ggcacccggt atctacgtct gcaacgccac caaccgccac     1860

ggctccgtgg ccaaaacagt cgtcgtgagc gcggagtcgc caccggagat ggatgaatct     1920

acctgcccaa gtcaccagac gtggctggaa ggggctgagg cttccgcgct ggcctgcgcc     1980

gcccggggtc gcccttcccc aggagtgcgc tgctctcggg aaggcatccc atggcctgag     2040

cagcagcgcg tgtcccgaga ggacgcgggc acttaccact gtgtggccac caatgcgcat     2100

ggcacggact cccggaccgt cactgtgggc gtggaatacc ggccagtggt ggccgaactt     2160

gctgcctcgc cccctggagg cgtgcgccca ggaggaaact tcacgttgac ctgccgcgcg     2220

gaggcctggc ctccagccca gatcagctgg cgcgcgcccc cgggggccct caacatcggc     2280

ctgtcgagca acaacagcac actgagcgtg gcaggcgcca tgggaagcca cggcggcgag     2340

tacgagtgcg cagccaccaa cgcgcacggg cgccacgcgc ggcgcatcac ggtgcgcgtg     2400

gccggtccgt gg                                                         2412


<210>  3668
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3668
gaaatcaatg gttctgccaa ttatgagatg tttatatttc acaacggagg tgtacaaatt       60

ttatgcaaat atcctgacat tgtccagcaa tttaaaatgc agttgctgaa aggggggcaa      120

atactctgcg atctcactaa gacaaaagga agtggaaaca cagtgtccat taagagtctg      180

aaattctgcc attctcagtt atccaacaac agtgtctctt tttttctata caacttggac      240

cattctcatg ccaactatta cttctgcaac ctatcaattt ttgatcctcc tccttttaaa      300

gtaactctta caggaggata tttgcatatt tatgaatcac aactttgttg ccagctgaag      360


<210>  3669
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  3669
gatactcagg agaaggaagt cagagcgatg gtaggcagcg acgtggagct cagctgcgct       60

tgccctgaag gaagccgttt tgatttaaat gatgtttacg tatattggca aaccagtgag      120

tcgaaaaccg tggtgaccta ccacatccca cagaacagct ccttggaaaa cgtggacagc      180

cgctaccgga accgagccct gatgtcaccg gccggcatgc tgcggggcga cttctccctg      240

cgcttgttca acgtcacccc ccaggacgag cagaagtttc actgcctggt gttgagccaa      300

tccctgggat tccaggaggt tttgagcgtt gaggttacac tgcatgtggc agcaaacttc      360

agcgtgcccg tcgtcagcgc cccccacagc ccctcccagg atgagctcac cttcacgtgt      420

acatccataa acggctaccc caggcccaac gtgtactgga tcaataagac ggacaacagc      480

ctgctggacc aggctctgca gaatgacacc gtcttcttga acatgcgggg cttgtatgac      540

gtggtcagcg tgctgaggat cgcacggacc cccagcgtga acattggctg ctgcatagag      600

aacgtgcttc tgcagcagaa cctgactgtc ggcagccaga caggaaatga catcggagag      660

agagacaaga tcacagagaa tccagtcagt accggcgaga aaaacgcggc cacg            714


<210>  3670
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  3670
atgagggagg ggaagagggg accgccatgt attttgtcct ttaggggaac tctggaaagg       60

gttgaagcac aatgggaatt ggaggcgcaa gggcctggac aatgccctgc acccctggga      120

gaccctgcct ctactactga tggcgcacaa gaagccagag tacctctgga tggcgctttt      180

tggatcccgc gtcctccagc gggtagtcca aaaggatgct tcgcgtgcgt ctcaaaaccc      240

ccagcattac aggcacctgc tgccccggcc cctgagccca gtgcgtctcc cccgatggct      300

cctactctgt ttccaatgga gtcaaagagc tccaagaccg attcagttag ggctgccggg      360

gcgccaccag cttgcaaaca cttagcggag aaaaagacca tgacaaaccc tactaccgta      420

atagaggtat atccagatac tactgaagta aatgattatt ac                         462


<210>  3671
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3671
tgtgatctgc ctcagaccca cagcctgggt aataggaggg ccttgatact cctgggacaa       60

atgggaagaa tctctccttt ctcctgcctg aaggacagac atgatttccg aatcccccag      120

gaggagtttg atggcaacca gttccagaag gctcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca gaggactcat ctgctgcttg ggaacagagc      240

ctcctagaaa aattttccac tgaactttac cagcaactga atgacctgga agcatgtgtg      300

atacaggagg ttggggtgga agagactccc ctgatgaatg aggactccat cctggctgtg      360

aggaaatact tccaaagaat cactctttat ctaatagaga ggaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccctctcgt tttcaacaaa cttgcaaaaa      480

agattaagga ggaaggat                                                    498


<210>  3672
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3672
tgtgatctcc ctgagaccca cagcttggat aacaggagga ccttgatgct cctggcacaa       60

atgagcagaa tctctccttc ctcctgtctg atggacagac atgactttgg atttccccag      120

gaggagtttg atggcaacca gttccagaag gctccagcca tctctgtcct ccatgagctg      180

atccagcaga tcttcaacct ctttaccaca aaagattcat ctgctgcttg ggatgaggac      240

ctcctagaca aattctgcac cgaactctac cagcagctga atgacttgga agcctgtgtg      300

atgcaggagg agagggtggg agaaactccc ctgatgaatg cggactccat cttggctgtg      360

aagaaatact tccgaagaat cactctctat ctgacagaga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccctctctt tatcaacaaa cttgcaagaa      480

agattaagga ggaaggaa                                                    498


<210>  3673
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3673
tgtaatctgt ctcaaaccca cagcctgaat aacaggagga ctttgatgct catggcacaa       60

atgaggagaa tctctccttt ctcctgcctg aaggacagac atgactttga atttccccag      120

gaggaatttg atggcaacca gttccagaaa gctcaagcca tctctgtcct ccatgagatg      180

atgcagcaga ccttcaatct cttcagcaca aagaactcat ctgctgcttg ggatgagacc      240

ctcctagaaa aattctacat tgaacttttc cagcaaatga atgacctgga agcctgtgtg      300

atacaggagg ttggggtgga agagactccc ctgatgaatg aggactccat cctggctgtg      360

aagaaatact tccaaagaat cactctttat ctgatggaga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccctctctt tttcaacaaa cttgcaaaaa      480

agattaagga ggaaggat                                                    498


<210>  3674
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3674
tgtgatctgc ctcagactca cagcctgggt aataggaggg ccttgatact cctggcacaa       60

atgggaagaa tctctcattt ctcctgcctg aaggacagat atgatttcgg attcccccag      120

gaggtgtttg atggcaacca gttccagaag gctcaagcca tctctgcctt ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca aaggattcat ctgctgcttg ggatgagacc      240

ctcctagaca aattctacat tgaacttttc cagcaactga atgacctaga agcctgtgtg      300

acacaggagg ttggggtgga agagattgcc ctgatgaatg aggactccat cctggctgtg      360

aggaaatact ttcaaagaat cactctttat ctgatgggga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccttctctt tttcaacaaa cttgcaaaaa      480

ggattaagaa ggaaggat                                                    498


<210>  3675
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3675
tgtgacctac ctcagaccca ctcattaggc aaccgtcgtg ccctgattct tctagcgcaa       60

atgggaagga tttccccttt ctcatgtctt aaggacagac atgactttgg acttccacaa      120

gaagaatttg atgggaacca gttccagaag acgcaggcta tttcagtgtt acatgagatg      180

atccaacaga ccttcaatct attctctaca gaggactcaa gcgctgcatg ggaacaatcc      240

cttcttgaga agttcagcac agagctttac caacaactga acaatttgga agcgtgtgtg      300

attcaggagg ttggcatgga agaaactcca ctgatgaacg aagactctat attggcggtt      360

cgtaagtatt ttcaacgtat taccctttat ttgactgaaa agaaatacag cccctgtgcg      420

tgggaagtgg tacgtgctga aataatgcgt agtttgtctt tttctacgaa cctacagaag      480

atccttagga gaaaagac                                                    498


<210>  3676
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3676
tgtgatctgc ctcagaccca cagcctgggt aataggaggg ccttgatact cctggcacaa       60

atgggaagaa tctctccttt ctcctgcctg aaggacagac atgactttgg acttccccag      120

gaggagtttg atggcaacca gttccagaag actcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca gaggactcat ctgctgcttg ggaacagagc      240

ctcctagaaa aattttccac tgaactttac cagcaactga ataacctgga agcatgtgtg      300

atacaggagg ttgggatgga agagactccc ctgatgaatg aggactccat cctggctgtg      360

aggaaatact tccaaagaat cactctttat ctaacagaga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tctctctctt tttcaacaaa cttgcaaaaa      480

atattaagga ggaaggat                                                    498


<210>  3677
<211>  495
<212>  DNA
<213>  Homo Sapiens

<400>  3677
tgtgatctgc ctcaaaccca cagcctgggt agcaggagga ccttgatgct cctggcacag       60

atgaggagaa tctctctttt ctcctgcttg aaggacagac atgactttgg atttccccag      120

gaggagtttg gcaaccagtt ccaaaaggct gaaaccatcc ctgtcctcca tgagatgatc      180

cagcagatct tcaatctctt cagcacaaag gactcatctg ctgcttggga tgagaccctc      240

ctagacaaat tctacactga actctaccag cagctgaatg acctggaagc ctgtgtgata      300

cagggggtgg gggtgacaga gactcccctg atgaaggagg actccattct ggctgtgagg      360

aaatacttcc aaagaatcac tctctatctg aaagagaaga aatacagccc ttgtgcctgg      420

gaggttgtca gagcagaaat catgagatct ttttctttgt caacaaactt gcaagaaagt      480

ttaagaagta aggaa                                                       495


<210>  3678
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3678
tgtgatctgc ctcagaccca cagcctgggt aataggaggg ccttgatact cctggcacaa       60

atgggaagaa tctctccttt ctcctgcctg aaggacagac atgactttgg attcccccag      120

gaggagtttg atggcaacca gttccagaag gctcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca aaggactcat ctgctacttg ggaacagagc      240

ctcctagaaa aattttccac tgaacttaac cagcagctga atgacctgga agcctgcgtg      300

atacaggagg ttggggtgga agagactccc ctgatgaatg tggactccat cctggctgtg      360

aagaaatact tccaaagaat cactctttat ctgacagaga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccttctctt tatcaaaaat ttttcaagaa      480

agattaagga ggaaggaa                                                    498


<210>  3679
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3679
tgtgatctgc ctcagaccca cagcctgggt aataggaggg ccttgatact cctggcacaa       60

atgggaagaa tctctcattt ctcctgcctg aaggacagac atgatttcgg attccccgag      120

gaggagtttg atggccacca gttccagaag gctcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca gaggactcat ctgctgcttg ggaacagagc      240

ctcctagaaa aattttccac tgaactttac cagcaactga atgacctgga agcatgtgtg      300

atacaggagg ttggggtgga agagactccc ctgatgaatg aggactccat cctggctgtg      360

aggaaatact tccaaagaat cactctttat ctaacagaga agaaatacag cccttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccctctcgt tttcaacaaa cttgcaaaaa      480

agattaagga ggaaggat                                                    498


<210>  3680
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3680
tgtgatctgc ctcagaccca cagcctgagt aacaggagga ctttgatgat aatggcacaa       60

atgggaagaa tctctccttt ctcctgcctg aaggacagac atgactttgg atttcctcag      120

gaggagtttg atggcaacca gttccagaag gctcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaatct cttcagcaca aaggactcat ctgctacttg ggatgagaca      240

cttctagaca aattctacac tgaactttac cagcagctga atgacctgga agcctgtatg      300

atgcaggagg ttggagtgga agacactcct ctgatgaatg tggactctat cctgactgtg      360

agaaaatact ttcaaagaat caccctctat ctgacagaga agaaatacag cccttgtgca      420

tgggaggttg tcagagcaga aatcatgaga tccttctctt tatcagcaaa cttgcaagaa      480

agattaagga ggaaggaa                                                    498


<210>  3681
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  3681
tctctggact gtgatctgcc tcagacccac agcctgggtc acaggaggac catgatgctc       60

ctggcacaaa tgaggagaat ctctcttttc tcctgtctga aggacagaca tgacttcaga      120

tttccccagg aggagtttga tggcaaccag ttccagaagg ctgaagccat ctctgtcctc      180

catgaggtga ttcagcagac cttcaacctc ttcagcacaa aggactcatc tgttgcttgg      240

gatgagaggc ttctagacaa actctatact gaactttacc agcagctgaa tgacctggaa      300

gcctgtgtga tgcaggaggt gtgggtggga gggactcccc tgatgaatga ggactccatc      360

ctggctgtga gaaaatactt ccaaagaatc actctctacc tgacagagaa aaagtacagc      420

ccttgtgcct gggaggttgt cagagcagaa atcatgagat ccttctcttc atcaagaaac      480

ttgcaagaaa ggttaaggag gaaggaa                                          507


<210>  3682
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3682
tgtgatctgc ctcagactca cagcctgggt aacaggaggg ccttgatact cctggcacaa       60

atgcgaagaa tctctccttt ctcctgcctg aaggacagac atgactttga attcccccag      120

gaggagtttg atgataaaca gttccagaag gctcaagcca tctctgtcct ccatgagatg      180

atccagcaga ccttcaacct cttcagcaca aaggactcat ctgctgcttt ggatgagacc      240

cttctagatg aattctacat cgaacttgac cagcagctga atgacctgga gtcctgtgtg      300

atgcaggaag tgggggtgat agagtctccc ctgatgtacg aggactccat cctggctgtg      360

aggaaatact tccaaagaat cactctatat ctgacagaga agaaatacag ctcttgtgcc      420

tgggaggttg tcagagcaga aatcatgaga tccttctctt tatcaatcaa cttgcaaaaa      480

agattgaaga gtaaggaa                                                    498


<210>  3683
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  3683
aaaaatctaa aatctcctca aaaagtagag gtcgacatca tagatgacaa ctttatcctg       60

aggtggaaca ggagcgatga gtctgtcggg aatgtgactt tttcattcga ttatcaaaaa      120

actgggatgg ataattggat aaaattgtct gggtgtcaga atattactag taccaaatgc      180

aacttttctt cactcaagct gaatgtttat gaagaaatta aattgcgtat aagagcagaa      240

aaagaaaaca cttcttcatg gtatgaggtt gactcattta caccatttcg caaagctcag      300

attggtcctc cagaagtaca tttagaagct gaagataagg caatagtgat acacatctct      360

cctggaacaa aagatagtgt tatgtgggct ttggatggtt taagctttac atatagctta      420

gttatctgga aaaactcttc aggtgtagaa gaaaggattg aaaatattta ttccagacat      480

aaaatttata aactctcacc agagactact tattgtctaa aagttaaagc agcactactt      540

acgtcatgga aaattggtgt ctatagtcca gtacattgta taaagaccac agttgaaaat      600

gaactacctc caccagaaaa tatagaagtc agtgtccaaa atcagaacta tgttcttaaa      660

tgggattata catatgcaaa catgaccttt caagttcagt ggctccacgc ctttttaaaa      720

aggaatcctg gaaaccattt gtataaatgg aaacaaatac ctgactgtga aaatgtcaaa      780

actacccagt gtgtctttcc tcaaaacgtt ttccaaaaag gaatttacct tctccgcgta      840

caagcatctg atggaaataa cacatctttt tggtctgaag agataaagtt tgatactgaa      900

atacaagctt tcctacttcc tccagtcttt aacattagat cccttagtga ttcattccat      960

atctatatcg gtgctccaaa acagtctgga aacacgcctg tgatccagga ttatccactg     1020

atttatgaaa ttattttttg ggaaaacact tcaaatgctg agagaaaaat tatcgagaaa     1080

aaaactgatg ttacagttcc taatttgaaa ccactgactg tatattgtgt gaaagccaga     1140

gcacacacca tggatgaaaa gctgaataaa agcagtgttt ttagtgacgc tgtatgtgag     1200

aaaacaaaac caggaaatac ctctaaa                                         1227


<210>  3684
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  3684
atttcatatg attcgcctga ttacacagat gaatcttgca ctttcaagat atcattgcga       60

aatttccggt ccatcttatc atgggaatta aaaaaccact ccattgtacc aactcactat      120

acattgctgt atacaatcat gagtaaacca gaagatttga aggtggttaa gaactgtgca      180

aataccacaa gatcattttg tgacctcaca gatgagtgga gaagcacaca cgaggcctat      240

gtcaccgtcc tagaaggatt cagcgggaac acaacgttgt tcagttgctc acacaatttc      300

tggctggcca tagacatgtc ttttgaacca ccagagtttg agattgttgg ttttaccaac      360

cacattaatg tgatggtgaa atttccatct attgttgagg aagaattaca gtttgattta      420

tctctcgtca ttgaagaaca gtcagaggga attgttaaga agcataaacc cgaaataaaa      480

ggaaacatga gtggaaattt cacctatatc attgacaagt taattccaaa cacgaactac      540

tgtgtatctg tttatttaga gcacagtgat gagcaagcag taataaagtc tcccttaaaa      600

tgcaccctcc ttccacctgg ccaggaatca gaatcagcag aatctgccaa a               651


<210>  3685
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  3685
atgagctaca acttgcttgg attcctacaa agaagcagca attttcagtg tcagaagctc       60

ctgtggcaat tgaatgggag gcttgaatac tgcctcaagg acaggatgaa ctttgacatc      120

cctgaggaga ttaagcagct gcagcagttc cagaaggagg acgccgcatt gaccatctat      180

gagatgctcc agaacatctt tgctattttc agacaagatt catctagcac tggctggaat      240

gagactattg ttgagaacct cctggctaat gtctatcatc agataaacca tctgaagaca      300

gtcctggaag aaaaactgga gaaagaagat ttcaccaggg gaaaactcat gagcagtctg      360

cacctgaaaa gatattatgg gaggattctg cattacctga aggccaagga gtacagtcac      420

tgtgcctgga ccatagtcag agtggaaatc ctaaggaact tttacttcat taacagactt      480

acaggttacc tccgaaac                                                    498


<210>  3686
<211>  561
<212>  DNA
<213>  Homo Sapiens

<400>  3686
ctagatttga aactgattat cttccagcaa agacaagtga atcaagaaag tttaaaactc       60

ttgaataagt tgcaaacctt gtcaattcag cagtgtctac cacacaggaa aaactttctg      120

cttcctcaga agtctttgag tcctcagcag taccaaaaag gacacactct ggccattctc      180

catgagatgc ttcagcagat cttcagcctc ttcagggcaa atatttctct ggatggttgg      240

gaggaaaacc acacggagaa attcctcatt caacttcatc aacagctaga atacctagaa      300

gcactcatgg gactggaagc agagaagcta agtggtactt tgggtagtga taaccttaga      360

ttacaagtta aaatgtactt ccgaaggatc catgattacc tggaaaacca ggactacagc      420

acctgtgcct gggccattgt ccaagtagaa atcagccgat gtctgttctt tgtgttcagt      480

ctcacagaaa aactgagcaa acaaggaaga cccttgaacg acatgaagca agagcttact      540

acagagttta gaagcccgag g                                                561


<210>  3687
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  3687
caggacccat atgtaaaaga agcagaaaac cttaagaaat attttaatgc aggtcattca       60

gatgtagcgg ataatggaac tcttttctta ggcattttga agaattggaa agaggagagt      120

gacagaaaaa taatgcagag ccaaattgtc tccttttact tcaaactttt taaaaacttt      180

aaagatgacc agagcatcca aaagagtgtg gagaccatca aggaagacat gaatgtcaag      240

tttttcaata gcaacaaaaa gaaacgagat gacttcgaaa agctgactaa ttattcggta      300

actgacttga atgtccaacg caaagcaata catgaactca tccaagtgat ggctgaactg      360

tcgccagcag ctaaaacagg gaagcgaaaa aggagtcaga tgctgtttcg aggt            414


<210>  3688
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  3688
gagatgggca ccgcggatct ggggccgtcc tcagtgccta caccaactaa tgttacaatt       60

gaatcctata acatgaaccc tatcgtatat tgggagtacc agatcatgcc acaggtccct      120

gtttttaccg tagaggtaaa gaactatggt gttaagaatt cagaatggat tgatgcctgc      180

atcaatattt ctcatcatta ttgtaatatt tctgatcatg ttggtgatcc atcaaattct      240

ctttgggtca gagttaaagc cagggttgga caaaaagaat ctgcctatgc aaagtcagaa      300

gaatttgctg tatgccgaga tggaaaaatt ggaccaccta aactggatat cagaaaggag      360

gagaagcaaa tcatgattga catatttcac ccttcagttt ttgtaaatgg agacgagcag      420

gaagtcgatt atgatcccga aactacctgt tacattaggg tgtacaatgt gtatgtgaga      480

atgaacggaa gtgagatcca gtataaaata ctcacgcaga aggaagatga ttgtgacgag      540

attcagtgcc agttagcgat tccagtatcc tcactgaatt ctcagtactg tgtttcagca      600

gaaggagtct tacatgtgtg gggtgttaca actgaaaagt caaaagaagt ttgtattacc      660

attttcaata gcagtataaa aggt                                             684


<210>  3689
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  3689
tcccagctgc ccgctcctca gcacccgaag attcgcctgt acaacgcaga gcaggtcctg       60

agttgggagc cagtggccct gagcaatagc acgaggcctg ttgtctacca agtgcagttt      120

aaatacaccg acagtaaatg gttcacggcc gacatcatgt ccataggggt gaattgtaca      180

cagatcacag caacagagtg tgacttcact gccgccagtc cctcagcagg cttcccaatg      240

gatttcaatg tcactctacg ccttcgagct gagctgggag cactccattc tgcctgggtg      300

acaatgcctt ggtttcaaca ctatcggaat gtgactgtcg ggcctccaga aaacattgag      360

gtgaccccag gagaaggctc cctcatcatc aggttctcct ctccctttga catcgctgat      420

acctccacgg cctttttttg ttattatgtc cattactggg aaaaaggagg aatccaacag      480

gtcaaaggcc ctttcagaag caactccatt tcattggata acttaaaacc ctccagagtg      540

tactgtttac aagtccaggc acaactgctt tggaacaaaa gtaacatctt tagagtcggg      600

catttaagca acatatcttg ctacgaaaca atggcagatg cctccactga gcttcagcaa      660


<210>  3690
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  3690
ctggactgta acttactgaa cgttcacctg agaagagtca cctggcaaaa tctgagacat       60

ctgagtagta tgagcaattc atttcctgta gaatgtctac gagaaaacat agcttttgag      120

ttgccccaag agtttctgca atacacccaa cctatgaaga gggacatcaa gaaggccttc      180

tatgaaatgt ccctacaggc cttcaacatc ttcagccaac acaccttcaa atattggaaa      240

gagagacacc tcaaacaaat ccaaatagga cttgatcagc aagcagagta cctgaaccaa      300

tgcttggagg aagacaagaa tgaaaatgaa gacatgaaag aaatgaaaga gaatgagatg      360

aaaccctcag aagccagggt cccccagctg agcagcctgg aactgaggag atatttccac      420

aggatagaca atttcctgaa agaaaagaaa tacagtgact gtgcctggga gattgtccga      480

gtggaaatca gaagatgttt gtattacttt tacaaattta cagctctatt caggaggaaa      540


<210>  3691
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3691
gttcctgtcg ccaggctcca cggggctctc ccggatgcaa ggggctgcca catagcccag       60

ttcaagtccc tgtctccaca ggagctgcag gcctttaaga gggccaaaga tgccttagaa      120

gagtcgcttc tgctgaagga ctgcaggtgc cactcccgcc tcttccccag gacctgggac      180

ctgaggcagc tgcaggtgag ggagcgcccc atggctttgg aggctgagct ggccctgacg      240

ctgaaggttc tggaggccac cgctgacact gacccagccc tggtggacgt cttggaccag      300

ccccttcaca ccctgcacca tatcctctcc cagttccggg cctgtatcca gcctcagccc      360

acggcagggc ccaggacccg gggccgcctc caccattggc tgtaccggct ccaggaggcc      420

ccaaaaaagg agtcccctgg ctgcctcgag gcctctgtca ccttcaacct cttccgcctc      480

ctcacgcgag acctgaattg tgttgccagt ggggacctgt gtgtc                      525


<210>  3692
<211>  522
<212>  DNA
<213>  Homo Sapiens

<400>  3692
ctgggctgtg atctgcctca gaaccatggc ctacttagca ggaacacctt ggtgcttctg       60

caccaaatga ggagaatctc ccctttcttg tgtctcaagg acagaagaga cttcaggttc      120

ccccaggaga tggtaaaagg gagccagttg cagaaggccc atgtcatgtc tgtcctccat      180

gagatgctgc agcagatctt cagcctcttc cacacagagc gctcctctgc tgcctggaac      240

atgaccctcc tagaccaact ccacactgga cttcatcagc aactgcaaca cctggagacc      300

tgcttgctgc aggtagtggg agaaggagaa tctgctgggg caattagcag ccctgcactg      360

accttgagga ggtacttcca gggaatccgt gtctacctga aagagaagaa atacagcgac      420

tgtgcctggg aagttgtcag aatggaaatc atgaaatcct tgttcttatc aacaaacatg      480

caagaaagac tgagaagtaa agatagagac ctgggctcat ct                         522


<210>  3693
<211>  1815
<212>  DNA
<213>  Homo Sapiens

<400>  3693
cttggccact ctgccgaact ggcatttgct gtggagccaa gtgatgatgt tgccgtcccc       60

gggcagccta tagtgctgga ctgcagggtg gaggggaccc ctccagtgcg aatcacctgg      120

aggaagaatg gggtagagct gccagagagt acccactcca ccttgctggc caatgggtcc      180

ttgatgatcc gtcacttcag gctggagccg ggaggcagcc cttcggatga aggtgactat      240

gagtgtgtgg cccagaaccg ctttgggctg gtggtcagcc ggaaggctcg catccaagct      300

gcaaccatgt cggacttcca cgtgcatccc caggccaccg tgggtgagga gggtggtgtg      360

gcccgcttcc agtgccaaat ccatgggctt cccaaacccc tgatcacttg ggagaagaac      420

agagtcccaa ttgacacgga caatgagagg tacacattgc tgcccaaggg ggtcctgcag      480

atcacaggac ttcgagctga ggacggtggc atcttccact gtgtggcctc aaacatcgcc      540

agtatccgga tcagccacgg ggccaggctc actgtgtcag gctcgggctc tggggcctac      600

aaggagccag ccatcctcgt ggggcctgag aacctcaccc tgacagtgca ccagaccgcg      660

gtgcttgagt gtgtcgccac gggcaacccg cgccccattg tgtcctggag ccgcctggat      720

ggtcgcccta tcggggtgga gggcatccag gtgctgggca caggaaacct catcatctca      780

gacgtgacgg tccagcactc tggcgtctac gtctgtgcag ccaacagacc tggcacccgg      840

gtgaggagaa cggcacaggg ccggctggtg gtgcaagccc cagctgagtt tgtgcagcat      900

ccccagtcca tctccaggcc agctgggacc acagccatgt tcacctgcca agcccagggt      960

gagccaccgc ctcatgtcac gtggctgaaa aatggacagg tgctggggcc aggaggccac     1020

gtcaggctca agaataacaa cagcacactg accatttctg gaatcggtcc tgaggatgaa     1080

gccatttatc agtgtgtggc cgagaacagt gcgggctcat cacaggccag tgccaggctg     1140

accgtactgt gggctgaggg gctccccggg cctccccgca atgtgcgggc agtctctgtg     1200

tcttccactg aggtgcgtgt gtcctggagt gagccgctgg ccaacaccaa ggagatcatc     1260

ggctacgtcc tgcacatcag gaaggctgct gacccaccgg agctggagta tcaggaggca     1320

gtcagcaaga gcacctttca gcacctggtc agcgacctgg agccctccac agcctacagt     1380

ttctacatca aggcctacac accaaggggg gccagctcag cctctgtgcc caccctagct     1440

agcaccctgg gtgaagcccc tgccccaccc ccactgtcag tgcgagtcct gggcagctcc     1500

tccttgcagc tgctgtggga gccttggccc cggctggccc agcacgaggg cggcttcaag     1560

ctgttttacc gcccagcaag caagacctcc ttcaccggcc ccatcctgct gcctggaacc     1620

gtctcctcct acaacctcag ccagctcgac cccactgcag tgtatgaggt gaagctgctc     1680

gcctacaacc agcatggaga tggcaatgcc acagtccgct ttgtgtcttt gaggggagca     1740

tctgagagga cagccttgag cccaccatgt gactgccgga aggaggaggc cgccaaccag     1800

acgtccacca caggc                                                      1815


<210>  3694
<211>  101
<212>  DNA
<213>  Homo Sapiens

<400>  3694
tggtcctccg cgccagcttc gacgagagac agccttacgc ccacatgaac gggggccgca       60

agaacgagcg ggccttgccg ctgccccagt cttcgacctg c                          101


<210>  3695
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  3695
gcttaccgcc ccagtgagac cctgtgcggc ggggagctgg tggacaccct ccagttcgtc       60

tgtggggacc gcggcttcta cttcagcagg cccgcaagcc gtgtgagccg tcgcagccgt      120

ggcatcgttg aggagtgctg tttccgcagc tgtgacctgg ccctcctgga gacgtactgt      180

gctacccccg ccaagtccga g                                                201


<210>  3696
<211>  2760
<212>  DNA
<213>  Homo Sapiens

<400>  3696
tcaaggtaca gtgacaactg ggaagccatc actgggacgg gggacccgga gcactacctc       60

atcaatgtct gcaagtctct ggccccgcag gctggcactg agccgtgccc tccagaagca      120

gccgcgtgtc tgctgggtgg ctccaagccc gtgaacctcg gcagggtaag ggacggacct      180

cagtggagag atggcataat tgtcctgaaa tacgttgatg gcgacttatg tccagatggg      240

attcggaaaa agtcaaccac catccgattc acctgcagcg agagccaagt gaactccagg      300

cccatgttca tcagcgccgt ggaggactgt gagtacacct ttgcctggcc cacagccaca      360

gcctgtccca tgaagagcaa cgagcatgat gactgccagg tcaccaaccc aagcacagga      420

cacctgtttg atctgagctc cttaagtggc agggcgggat tcacagctgc ttacagcgag      480

aaggggttgg tttacatgag catctgtggg gagaatgaaa actgccctcc tggcgtgggg      540

gcctgctttg gacagaccag gattagcgtg ggcaaggcca acaagaggct gagatacgtg      600

gaccaggtcc tgcagctggt gtacaaggat gggtcccctt gtccctccaa atccggcctg      660

agctataaga gtgtgatcag tttcgtgtgc aggcctgagg ccgggccaac caataggccc      720

atgctcatct ccctggacaa gcagacatgc actctcttct tctcctggca cacgccgctg      780

gcctgcgagc aagcgaccga atgttccgtg aggaatggaa gctctattgt tgacttgtct      840

ccccttattc atcgcactgg tggttatgag gcttatgatg agagtgagga tgatgcctcc      900

gataccaacc ctgatttcta catcaatatt tgtcagccac taaatcccat gcacggagtg      960

ccctgtcctg ccggagccgc tgtgtgcaaa gttcctattg atggtccccc catagatatc     1020

ggccgggtag caggaccacc aatactcaat ccaatagcaa atgagattta cttgaatttt     1080

gaaagcagta ctccttgctt agcggacaag catttcaact acacctcgct catcgcgttt     1140

cactgtaaga gaggtgtgag catgggaacg cctaagctgt taaggaccag cgagtgcgac     1200

tttgtgttcg aatgggagac tcctgtcgtc tgtcctgatg aagtgaggat ggatggctgt     1260

accctgacag atgagcagct cctctacagc ttcaacttgt ccagcctttc cacgagcacc     1320

tttaaggtga ctcgcgactc gcgcacctac agcgttgggg tgtgcacctt tgcagtcggg     1380

ccagaacaag gaggctgtaa ggacggagga gtctgtctgc tctcaggcac caagggggca     1440

tcctttggac ggctgcaatc aatgaaactg gattacaggc accaggatga agcggtcgtt     1500

ttaagttacg tgaatggtga tcgttgccct ccagaaaccg atgacggcgt cccctgtgtc     1560

ttccccttca tattcaatgg gaagagctac gaggagtgca tcatagagag cagggcgaag     1620

ctgtggtgta gcacaactgc ggactacgac agagaccacg agtggggctt ctgcagacac     1680

tcaaacagct accggacatc cagcatcata tttaagtgtg atgaagatga ggacattggg     1740

aggccacaag tcttcagtga agtgcgtggg tgtgatgtga catttgagtg gaaaacaaaa     1800

gttgtctgcc ctccaaagaa gttggagtgc aaattcgtcc agaaacacaa aacctacgac     1860

ctgcggctgc tctcctctct caccgggtcc tggtccctgg tccacaacgg agtctcgtac     1920

tatataaatc tgtgccagaa aatatataaa gggcccctgg gctgctctga aagggccagc     1980

atttgcagaa ggaccacaac tggtgacgtc caggtcctgg gactcgttca cacgcagaag     2040

ctgggtgtca taggtgacaa agttgttgtc acgtactcca aaggttatcc gtgtggtgga     2100

aataagaccg catcctccgt gatagaattg acctgtacaa agacggtggg cagacctgca     2160

ttcaagaggt ttgatatcga cagctgcact tactacttca gctgggactc ccgggctgcc     2220

tgcgccgtga agcctcagga ggtgcagatg gtgaatggga ccatcaccaa ccctataaat     2280

ggcaagagct tcagcctcgg agatatttat tttaagctgt tcagagcctc tggggacatg     2340

aggaccaatg gggacaacta cctgtatgag atccaacttt cctccatcac aagctccaga     2400

aacccggcgt gctctggagc caacatatgc caggtgaagc ccaacgatca gcacttcagt     2460

cggaaagttg gaacctctga caagaccaag tactaccttc aagacggcga tctcgatgtc     2520

gtgtttgcct cttcctctaa gtgcggaaag gataagacca agtctgtttc ttccaccatc     2580

ttcttccact gtgaccctct ggtggaggac gggatccccg agttcagtca cgagactgcc     2640

gactgccagt acctcttctc ttggtacacc tcagccgtgt gtcctctggg ggtgggcttt     2700

gacagcgaga atcccgggga cgacgggcag atgcacaagg ggctgtcaga acggagccag     2760


<210>  3697
<211>  1734
<212>  DNA
<213>  Homo Sapiens

<400>  3697
gcagaccccg gaacgccggg ggaagccgag ggcccagcgt gcccggccgc ctgtgtctgc       60

agctacgatg acgacgcgga tgagctcagc gtcttctgca gctccaggaa cctcacgcgc      120

ctgcctgatg gagtcccggg cggcacccaa gccctgtggc tggacggcaa caacctctcg      180

tccgtccccc cggcagcctt ccagaacctc tccagcctgg gcttcctcaa cctgcagggc      240

ggccagctgg gcagcctgga gccacaggcg ctgctgggcc tagagaacct gtgccacctg      300

cacctggagc ggaaccagct gcgcagcctg gcactcggca cgtttgcaca cacgcccgcg      360

ctggcctcgc tcggcctcag caacaaccgt ctgagcaggc tggaggacgg gctcttcgag      420

ggcctcggca gcctctggga cctcaacctc ggctggaata gcctggcggt gctccccgat      480

gcggcgttcc gcggcctggg cagcctgcgc gagctggtgc tggcgggcaa caggctggcc      540

tacctgcagc ccgcgctctt cagcggcctg gccgagctcc gggagctgga cctgagcagg      600

aacgcgctgc gggccatcaa ggcaaacgtg ttcgtgcagc tgccccggct ccagaaactc      660

tacctggacc gcaacctcat cgctgccgtg gccccgggcg ccttcctggg cctgaaggcg      720

ctgcgatggc tggacctgtc ccacaaccgc gtggctggcc tcctggagga cacgttcccc      780

ggtctgctgg gcctgcgtgt gctgcggctg tcccacaacg ccatcgccag cctgcggccc      840

cgcaccttca aggacctgca cttcctggag gagctgcagc tgggccacaa ccgcatccgg      900

cagctggctg agcgcagctt tgagggcctg gggcagcttg aggtgctcac gctagaccac      960

aaccagctcc aggaggtcaa ggcgggcgct ttcctcggcc tcaccaacat ggcggtcatg     1020

aacctctctg ggaactgtct ccggaacctt ccggagcagg tgttccgggg cctgggcaag     1080

ctgcacagcc tgcacctgga gggcagctgc ctgggacgca tccgcccgca caccttcacc     1140

ggcctctcgg ggctccgccg actcttcctc aaggacaacg gcctcgtggg cattgaggag     1200

cagagcctgt gggggctggc ggagctgctg gagctcgacc tgacctccaa ccagctcacg     1260

cacctgcccc accgcctctt ccagggcctg ggcaagctgg agtacctgct gctctcccgc     1320

aaccgcctgg cagagctgcc ggcggacgcc ctgggccccc tgcagcgggc cttctggctg     1380

gacgtctcgc acaaccgcct ggaggcattg cccaacagcc tcttggcacc actggggcgg     1440

ctgcgctacc tcagcctcag gaacaactca ctgcggacct tcacgccgca gcccccgggc     1500

ctggagcgcc tgtggctgga gggtaacccc tgggactgtg gctgccctct caaggcgctg     1560

cgggacttcg ccctgcagaa ccccagtgct gtgccccgct tcgtccaggc catctgtgag     1620

ggggacgatt gccagccgcc cgcgtacacc tacaacaaca tcacctgtgc cagcccgccc     1680

gaggtcgtgg ggctcgacct gcgggacctc agcgaggccc actttgctcc ctgc           1734


<210>  3698
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  3698
tcctcttcgg acacctgcgg cccctgcgag ccggcctcct gcccgcccct gcccccgctg       60

ggctgcctgc tgggcgagac ccgcgacgcg tgcggctgct gccctatgtg cgcccgcggc      120

gagggcgagc cgtgcggggg tggcggcgcc ggcagggggt actgcgcgcc gggcatggag      180

tgcgtgaaga gccgcaagag gcggaagggt aaagccgggg cagcagccgg cggtccgggt      240

gtaagcggcg tgtgcgtgtg caagagccgc tacccggtgt gcggcagcga cggcaccacc      300

tacccgagcg gctgccagct gcgcgccgcc agccagaggg ccgagagccg cggggagaag      360

gccatcaccc aggtcagcaa gggcacctgc gagcaaggtc cttccatagt gacgcccccc      420

aaggacatct ggaatgtcac tggtgcccag gtgtacttga gctgtgaggt catcggaatc      480

ccgacacctg tcctcatctg gaacaaggta aaaaggggtc actatggagt tcaaaggaca      540

gaactcctgc ctggtgaccg ggacaacctg gccattcaga cccggggtgg cccagaaaag      600

catgaagtaa ctggctgggt gctggtatct cctctaagta aggaagatgc tggagaatat      660

gagtgccatg catccaattc ccaaggacag gcttcagcat cagcaaaaat tacagtggtt      720

gatgccttac atgaaatacc agtgaaaaaa ggtgaaggtg ccgagcta                   768


<210>  3699
<211>  759
<212>  DNA
<213>  Homo Sapiens

<400>  3699
cttgggatcc gcgacgtggg cggccggcgc cccaagtgtg gtccgtgccg gccagagggc       60

tgcccggcgc ctgcgccctg cccggcgccc gggatctcgg cgctcgacga gtgcggctgc      120

tgcgcccgct gcctgggagc cgagggcgcg agctgcgggg gccgcgccgg cgggcgctgt      180

ggccccggcc tggtatgcgc gagccaggcc gctggggcag cgcccgaggg caccgggctc      240

tgcgtgtgcg cgcagcgcgg caccgtctgc ggctccgacg gtcgctcgta ccccagcgtc      300

tgcgcgctgc gcctgcgcgc tcggcacacg ccccgcgcgc accccggtca cctgcacaag      360

gcgcgcgacg gcccttgcga gttcgctcct gtggtcgtcg ttcctccccg aagtgttcac      420

aacgtcaccg gggcgcaggt gggcctgtcc tgtgaagtga gggctgtgcc taccccagtc      480

atcacgtgga gaaaggtcac gaagtcccct gagggcaccc aagcactgga ggagctgcct      540

ggggaccatg tcaatatagc tgtccaagtg cgagggggcc cttctgacca tgaggccacg      600

gcctggattt tgatcaaccc cctgcgaaag gaggatgagg gtgtgtacca gtgccatgca      660

gccaacatgg tgggagaggc tgagtcccac agcacagtga cggttctaga tctgagtaaa      720

tacaggagct tccacttccc agctcccgat gaccgcatg                             759


<210>  3700
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  3700
gccccagtgg cccccatgac tccttacctg atgctgtgcc agccacacaa gagatgtggg       60

gacaagttct acgaccccct gcagcactgt tgctatgatg atgccgtcgt gcccttggcc      120

aggacccaga cgtgtggaaa ctgcaccttc agagtctgct ttgagcagtg ctgcccctgg      180

accttcatgg tgaagctgat aaaccagaac tgcgactcag cccggacctc ggatgacagg      240

ctttgtcgca gtgtcagc                                                    258


<210>  3701
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  3701
cccgctggct cagaaccatg gctgtgccag ccggcaccca ggtgtggaga caagatctac       60

aaccccttgg agcagtgctg ttacaatgac gccatcgtgt ccctgagcga gacccgccaa      120

tgtggtcccc cctgcacctt ctggccctgc tttgagctct gctgtcttga ttcctttggc      180

ctcacaaacg attttgttgt gaagctgaag gttcagggtg tgaattccca gtgccactca      240

tctcccatct ccagtaaatg tgaaagcaga agacgttttc cc                         282


<210>  3702
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  3702
actacagacg ctcctgttgg ctcaggactg tggctgtgcc agccgacacc caggtgtggg       60

aacaagatct acaacccttc agagcagtgc tgttatgatg atgccatctt atccttaaag      120

gagacccgcc gctgtggctc cacctgcacc ttctggccct gctttgagct ctgctgtccc      180

gagtcttttg gcccccagca gaagtttctt gtgaagttga gggttctggg tatgaagtct      240

cagtgtcact tatctcccat ctcccggagc tgtaccagga acaggaggca cgtcctgtac      300

cca                                                                    303


<210>  3703
<211>  69
<212>  DNA
<213>  Homo Sapiens

<400>  3703
aaatcaccat gtggaaacca agcaaacgtg ttgtgcatca gccggcttga gtttgttcaa       60

tatcaaagc                                                               69


<210>  3704
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  3704
ctgctgcgcc caacagctgc atcgcagagc agggccctgg gccctggagc ccctggagga       60

agcagccggt ccagcctgag gagccggtgg ggcaggttcc tgctccagcg cggctcctgg      120

actggcccca ggtgctggcc ccgggggttt caatccaagc ataactcagt gacgcatgtg      180

tttggcagcg ggacccagct caccgtttta agtcagccca aggccacccc ctcggtcact      240

ctgttcccgc cgtcctctga ggagctccaa gccaacaagg ctacactggt gtgtctcatg      300

aatgactttt atccgggaat cttgacggtg acctggaagg cagatggtac ccccatcacc      360

cagggcgtgg agatgaccac gccctccaaa cagagcaaca acaagtacgc ggccagcagc      420

tacctgagcc tgacgcccga gcagtggagg tcccgcagaa gctacagctg ccaggtcatg      480

cacgaaggga gcaccgtgga gaagacggtg gcccctgcag aatgttca                   528


<210>  3705
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  3705
gttctggcgc agccgccctc agtgtctggg gccccagggc agacggtcac catctcgtgc       60

actgggagca gcaccaacat cggggcgggt tatgctgtac actggtacca gcagtttcca      120

ggagcggccc ccaaagtcct catctatggt aactacaatc ggccctcagg ggtccctgac      180

cgattctctg gctccaagtc tggcacctca gcctccctgg ccatcactgg gctccaggct      240

gaagatgagg ctgattatta ctgccagtcg tatgacggca gcctgagtgg ttctgtcttc      300

ggagctggga ccaaggtcac cgtcctgggt cagcccaagg ccaaccccac tgtcactctg      360

ttcccgccct cctctgagga gctccaagcc aacaaggcca cactagtgtg tctgatcagt      420

gacttctacc cgggagctgt gacagtggcc tggaaggcag atggcagccc cgtcaaggcg      480

ggagtggaga ccaccaaacc ctccaaacag agcaacaaca agtacgcggc cagcagctac      540

ctgagcctga cgcccgagca gtggaagtcc cacagaagct acagctgcca ggtcacgcat      600

gaagggagca ccgtggagaa gacagtggcc cctacagaat gttca                      645


<210>  3706
<211>  918
<212>  DNA
<213>  Homo Sapiens

<400>  3706
caatcactag agtttaatag tccagccgat aattacactg tctgcgaagg tgataacgcc       60

accctgtcat gctttattga tgagcatgtc accagggtgg catggttaaa ccgttctaac      120

attctttatg caggaaatga caggtggaca tctgatccta gggttagact gttgataaat      180

acgccagagg aattcagtat ccttataaca gaggttggtt taggagacga gggtttgtac      240

acctgctctt ttcaaacaag acatcaaccc tataccacac aggtatatct gatcgtacac      300

gtaccggcga gaatcgtgaa tatttcatct cccgtgacgg tgaatgaagg gggcaatgtt      360

aatcttttat gtctggctgt gggtaggcca gaaccgacag tcacatggcg tcagctaagg      420

gatggtttta caagcgaggg cgaaatatta gaaataagtg acattcagag ggggcaagcc      480

ggggagtatg agtgtgtaac acacaacggc gtaaactctg cccccgatag tcgtagagtt      540

ctagtaaccg tcaattaccc tccgactata acagacgtaa cgtccgcccg tactgcatta      600

ggaagagcgg cgcttttgag atgcgaggct atggccgtgc caccagcaga ttttcagtgg      660

tataaggatg atagactttt atcatctggt acagccgagg gcctgaaagt acagacagag      720

aggacacgta gcatgctttt gttcgccaat gtctccgctc gtcattacgg caactacact      780

tgccgtgcgg ccaaccgttt gggtgctagt agtgcaagta tgcgtttgct taggccgggc      840

tccctagaga acagcgcgcc taggccccca ggccttttag cattgctatc cgctttgggc      900

tggctgtggt ggaggatg                                                    918


<210>  3707
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  3707
atgacatcga tagtgatgga ccctcaaccg gagttgtgga tagagtccaa ctacccccag       60

gccccttggg agaacatcac gctttggtgc cgaagcccct ctcggatatc aagcaagttc      120

ctgctgctga aggataagac acagatgacc tggatccgcc cttcccacaa gaccttccaa      180

gtttcattcc ttataggtgc ccttactgag tccaatgcag gtctttaccg gtgctgctac      240

tggaaggaga caggctggtc aaagcccagt aaagttctag agttggaggc accaggccaa      300

ctgcccaagc ccatcttctg gattcaggct gagacccccg ctcttcctgg gtgtaatgtt      360

aacatcctct gccatggctg gctgcaggat ttggtattca tgctgtttaa agagggatat      420

gcagagcctg tggattacca agtcccaact gggacaatgg ccatattctc cattgacaac      480

ctgacacctg aggatgaagg ggtttacatc tgccgcactc atatccagat gctccccacc      540

ctgtggtcag agcccagcaa ccccctgaag ctggttgtag caggactcta ccccaaacca      600

actttgacag cccatcctgg gcccatcatg gcacctggag aaagcctgaa tctcaggtgc      660

caagggccaa tctatggaat gacctttgct ctaatgaggg ttgaagactt ggagaagtcc      720

ttttaccaca agaagacaat aaaaaatgag gcaaatttct tcttccagtc tttgaagatc      780

caagatactg gacattacct ctgtttttac tatgacgcat catatagagg ttcactcctt      840

agtgatgtcc tgaaaatctg ggtaactgac actttcccca agacctggct acttgctcgg      900

cccagtgctg tggtccaaat gggtcagaat gtgagcctac ggtgtcgagg accagtggat      960

ggagtgggtc ttgcactcta taagaaagga gaagacaaac cacttcaatt tttggatgcc     1020

accagcatcg atgacaacac atcattcttc ctcaacaatg taacctacag tgatactggc     1080

atctatagct gccactatct tctcacctgg aagacctcca ttaggatgcc atcacacaac     1140

actgtggagc ttatggttgt agataagccc cccaaaccct ccctgtcagc ttggccaagc     1200

actgtgttca agctaggaaa ggccatcacc cttcagtgcc gagtatctca tccagtactg     1260

gaattttctc tggaatggga agaaagagaa acattccaaa aattctcagt aaacggagac     1320

ttcatcatca gtaatgttga cgggaaaggc acagggacct acagttgcag ctatcgcgta     1380

gagacacatc ctaacatctg gtcacatcgc agtgagcccc tgaagctgat ggggccagca     1440

ggctatctca cctggaatta cgttctgaat                                      1470


<210>  3708
<211>  1170
<212>  DNA
<213>  Homo Sapiens

<400>  3708
cctccattaa tcaatggtct gtatacaaat agaactgtta ttaaagccac agctgtgaga       60

cattccaaaa aacactttga ctgcagagct gaagggacac catctcctga agtcatgtgg      120

atcatgccag acaatatttt cctcacagcc ccatactatg gaagcagaat cacagtccat      180

aaaaatggaa ccttggaaat taggaatgtg aggctttcag attcagccga ctttatctgt      240

gtggcccgaa atgaaggtgg agagagcgtg ttggtagtac agttagaagt actggaaatg      300

ctgagaagac cgacatttag aaatccattt aatgaaaaaa tagttgccca gctgggaaag      360

tccacagcat tgaattgctc tgttgatggt aacccaccac ctgaaataat ctggatttta      420

ccaaatggca cacgattttc caatggacca caaagttatc agtatctgat agcaagcaat      480

ggttctttta tcatttctaa aacaactcgg gaggatgcag gaaaatatcg ctgtgcagct      540

aggaataaag ttggctatat tgagaaatta gtcatattag aaattggcca gaagccagtt      600

attcttacct atgcaccagg gacagtaaaa ggcatcagtg gagaatctct atcactgcat      660

tgtgtgtctg atggaatccc taagccaaat atcaaatgga ctatgccaag tggttatgta      720

gtagacaggc ctcaaattaa tgggaaatac atattgcatg acaatggcac cttagtcatt      780

aaagaagcaa cagcttatga cagaggaaac tatatctgta aggctcaaaa tagtgttggt      840

catacactga ttactgttcc agtaatgatt gtagcctacc ctccccgaat tacaaatcgt      900

ccacccagga gtattgtcac caggacaggg gcagcctttc agctccactg tgtggccttg      960

ggagttccca agccagaaat cacgtgggag atgcctgacc actcccttct ctcaacggca     1020

agtaaagaga ggacacatgg aagtgagcag cttcacttac aaggtaccct agtcattcag     1080

aatccccaaa cctccgattc tgggatatac aaatgcacag caaagaaccc acttggtagt     1140

gattatgcag caacgtatat tcaagtaatc                                      1170


<210>  3709
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3709
ctggaagtgt cagagagccc tgggagtatc caggtggccc ggggtcagac agcagtcctg       60

ccctgcactt tcactaccag cgctgccctc attaacctca atgtcatttg gatggtcact      120

cctctctcca atgccaacca acctgaacag gtcatcctgt atcagggtgg acagatgttt      180

gatggtgccc cccggttcca cggtagggta ggatttacag gcaccatgcc agctaccaat      240

gtctctatct tcattaataa cactcagtta tcagacactg gcacctacca gtgcctggtc      300

aacaaccttc cagacatagg gggcaggaac attggggtca ccggtctcac agtgttagtt      360

cccccttctg ccccacactg ccaaatccaa ggatcccagg atattggcag cgatgtcatc      420

ctgctctgta gctcagagga aggcattcct cgaccaactt acctttggga gaagttagac      480

aataccctca aactacctcc aacagctact caggaccagg tccagggaac agtcaccatc      540

cggaacatca gtgccctgtc ttcaggtttg taccagtgcg tggcttctaa tgctattgga      600

accagcacct gtcttctgga tctccaggtt atttcacccc agcccaggaa cattgga         657


<210>  3710
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3710
tacctgacag tcaacattga gcctctcccc cctgtggtgg ctggagacgc cgtgactttg       60

aagtgtaact tcaagacaga tgggcgcatg cgggagatcg tgtggtaccg ggtgacggat      120

ggtggcacca tcaagcaaaa gatcttcacc ttcgacgcca tgttctccac caactactca      180

cacatggaga actaccgcaa gcgagaggac ctggtgtacc agtccactgt gaggctgccc      240

gaggtccgga tctcagacaa tggtccctat gagtgccatg tgggcatcta cgaccgcgcc      300

accagggaga aggtggtcct ggcatcaggc aacatcttcc tcaacgtcat ggctcctccc      360

acctccattg aagtggtggc tgctgacaca ccagccccct tcagccgcta ccaagcccag      420

aacttcacgc tggtctgcat cgtgtctgga ggaaaaccag cacccatggt ttatttcaaa      480

cgagatgggg aaccaatcga cgcagtgccc ctatcagagc caccagctgc gagctccggc      540

cccctacagg acagcaggcc cttccgcagc cttctgcacc gtgacctgga tgacaccaag      600

atgcagaagt cactgtccct cctggacgcc gagaaccggg gtgggcgacc ctacacggag      660

cgcccctccc gtggcctgac cccagatccc aacatcctcc tccagccaac cacagagaac      720

ataccagaga cggtcgtgag ccgtgagttt ccccgctggg tccacagcgc cgagcccacc      780

tacttcctgc gccacagccg caccccgagc agtgacggca ctgtggaagt acgtgccctg      840

ctcacctgga ccctcaaccc acagatcgac aacgaggccc tcttcagctg cgaggtcaag      900

cacccagctc tgtcgatgcc catgcaggca gaggtcacgc tggttgcccc caaaggaccc      960

aaaattgtga tgacgcccag cagagcccgg gtaggggaca cagtgaggat tctggtccat     1020

gggtttcaga acgaagtctt cccggagccc atgttcacgt ggacgcgggt tgggagccgc     1080

ctcctggacg gcagcgctga gttcgacggg aaggagctgg tgctggagcg ggttcccgcc     1140

gagctcaatg gctccatgta tcgctgcacc gcccagaacc cactgggctc caccgacacg     1200

cacacccggc tcatcgtgtt tgaaaaccca aatatcccaa gaggaacgga ggactctaat     1260


<210>  3711
<211>  3318
<212>  DNA
<213>  Homo Sapiens

<400>  3711
cagcggcagg tcaccgttca ggaaggaccc ttgtaccgca cggagggctc ccacatcact       60

atctggtgca atgtgagtgg ctaccaggga ccttctgagc agaatttcca gtggtccatt      120

tacctgcctt cgtcgccaga gcgagaggtg cagatcgtca gcaccatgga ctcttccttc      180

ccctatgcca tctacaccca gcgcgtccgc ggagggaaga tcttcataga aagagtccag      240

gggaactcaa ccctattgca catcacagat cttcaggccc gggatgccgg ggagtatgaa      300

tgccacacac ccagcactga taagcaatac tttgggagtt acagtgcaaa gatgaaccta      360

gtggtgatcc cagactccct gcagaccact gccatgcccc agactctgca cagagtggag      420

caggacccgc tggagctcac ttgtgaggtg gcctcagaga ccattcagca cagccacctg      480

tctgtggcct ggctccggca gaaagttggc gagaagcccg tggaggtcat ctccctgagc      540

cgagatttca tgcttcactc cagcagcgaa tatgcccaga ggcagagcct gggggaggtg      600

cggctggaca agctggggag gaccaccttc cgcctcacca tcttccacct gcagccttct      660

gaccagggcg aattctactg cgaggccgcc gagtggatcc aggatccgga tgggtcgtgg      720

tatgctatga cccgaaagcg ttccgaggga gccgtggtca acgtccagcc aactgacaaa      780

gaattcactg ttcggctgga gacagagaag cggctgcaca cggtgggcga gccggtggag      840

ttcagatgca tcctggaggc tcagaatgtt cccgaccgtt actttgctgt ctcctgggcc      900

ttcaacagct cgctcatcgc caccatgggt cctaacgctg tgcctgtcct caacagcgaa      960

tttgctcacc gggaagccag gggacagctt aaggtggcca aagagagcga cagtgtcttt     1020

gtgctgaaga tctaccacct ccgccaggaa gatagcggga aatacaactg ccgggtgact     1080

gagcgagaga aaaccgtgac cggggaattc attgataagg agagcaagcg tcccaagaac     1140

atccccatca tagtcctccc cctcaagagc agcatctccg tggaggtggc cagcaatgcc     1200

agcgtcatcc ttgagggcga ggacctgcgc ttctcctgca gtgtccgcac ggcaggcagg     1260

ccgcagggtc gcttctctgt catctggcag cttgtggaca ggcagaaccg ccgcagcaat     1320

atcatgtggc tagaccggga tggcaccgtg cagccaggct cgtcctactg ggagcgcagc     1380

agctttgggg gcgtccagat ggagcaggtg cagcccaact cgttcagcct gggcatcttc     1440

aacagcagga aggaggacga gggccagtat gaatgccatg tgactgaatg ggtgcgggca     1500

gtggatggcg agtggcagat tgttggggag cgccgggcca gcactcccat ctccatcaca     1560

gctcttgaaa tgggcttcgc agtcacagcc atctcccgga caccgggggt gacctacagc     1620

gactcctttg acttgcagtg tatcatcaaa ccccactacc ctgcctgggt ccccgtgtcg     1680

gtgacatggc ggttccagcc ggtgggcacg gtggagttcc atgacttggt gaccttcacc     1740

cgggacggag gggtccagtg gggggacagg tcctccagct tccgaacccg aactgccatc     1800

gagaaggctg agtccggcaa caacgtccgc ctaagcatca gccgagccag tgacacggaa     1860

gcaggcaagt accagtgtgt ggcagagctg tggcggaaga actacaacaa cacctggacg     1920

cgactggcgg agaggacctc caacctgctg gagatcaggg tgctgcagcc agtgacaaag     1980

ctgcaggtga gcaaatcgaa gaggaccctc accctggtgg aaaacaagcc cattcagttg     2040

aactgctcag tcaagtctca gactagccag aactcccact ttgcggtgct ctggtatgtc     2100

cacaagccct cggatgccga tggcaagctt atcctgaaga ccacccacaa ctccgccttt     2160

gaatacggta cttacgccga ggaggagggc ctgagagcca ggctccagtt tgagaggcat     2220

gtgtcggggg gcctgttcag cctcaccgtc cagagagccg aggtcagcga cagcggcagc     2280

tactactgcc acgtggagga gtggctgctg agccccaact acgcctggta caagctggca     2340

gaggaggttt ctgggcgcac agaagtcact gtgaaacagc cagacagccg cctgaggctc     2400

agccaagccc aggggaacct gtcggttctg gagacccggc aggtacagct ggagtgtgtg     2460

gttctcaacc gcaccagcat aacctcccag ctcatggtgg aatggtttgt atggaagccc     2520

aaccaccctg agcgggagac tgtggcccgc ttgagccgtg acgccacctt ccactatgga     2580

gagcaggcag ccaagaacaa tctgaagggg cggctgcatt tggagagtcc ttcccccggc     2640

gtgtaccgtc tcttcatcca gaacgtggct gtgcaggaca gcgggaccta cagctgccat     2700

gtggaggagt ggctgcccag ccccagtggc atgtggtata agcgggcaga ggacaccgct     2760

gggcagacag ctctgacagt catgcgacca gatgcttccc tgcaggtgga cacagtggtc     2820

cccaatgcca cggtctctga gaaggcagct ttccagctgg actgtagcat cgtgtcccgc     2880

tccagccagg actcccgctt cgctgtggcc tggtattccc tgaggactaa agctgggggg     2940

aaaaggagca gccctggcct ggaagaacag gaagaggaaa gggaggagga ggaggaggag     3000

gaggaggacg acgacgacga cgacccaaca gagcggacgg ccctgctgag cgtgggccca     3060

gatgctgtct ttggcccaga gggcagtcct tgggagggca ggcttcgctt ccagaggctc     3120

tccccggtgc tctaccggct cacagtgctg caggcaagcc cccaagatac aggcaattac     3180

tcctgccatg tggaggagtg gctgcccagc cctcagaagg aatggtaccg gctgacggag     3240

gaggagtcag cccccatcgg catccgtgtt ctagatacaa gtcccaccct ccagtccatc     3300

atctgctcca acgacgca                                                   3318


<210>  3712
<211>  918
<212>  DNA
<213>  Homo Sapiens

<400>  3712
aacctctccc aggacgacag ccagccctgg acatctgatg aaacagtggt ggctggtggc       60

accgtggtgc tcaagtgcca agtgaaagat cacgaggact catccctgca atggtctaac      120

cctgctcagc agactctcta ctttggggag aagagagccc ttcgagataa tcgaattcag      180

ctggttacct ctacgcccca cgagctcagc atcagcatca gcaatgtggc cctggcagac      240

gagggcgagt acacctgctc aatcttcact atgcctgtgc gaactgccaa gtccctcgtc      300

actgtgctag gaattccaca gaagcccatc atcactggtt ataaatcttc attacgggaa      360

aaagacacag ccaccctaaa ctgtcagtct tctgggagca agcctgcagc ccggctcacc      420

tggagaaagg gtgaccaaga actccacgga gaaccaaccc gcatacagga agatcccaat      480

ggtaaaacct tcactgtcag cagctcggtg acattccagg ttacccggga ggatgatggg      540

gcgagcatcg tgtgctctgt gaaccatgaa tctctaaagg gagctgacag atccacctct      600

caacgcattg aagttttata cacaccaact gcgatgatta ggccagaccc tccccatcct      660

cgtgagggcc agaagctgtt gctacactgt gagggtcgcg gcaatccagt cccccagcag      720

tacctatggg agaaggaggg cagtgtgcca cccctgaaga tgacccagga gagtgccctg      780

atcttccctt tcctcaacaa gagtgacagt ggcacctacg gctgcacagc caccagcaac      840

atgggcagct acaaggccta ctacaccctc aatgttaatg accccagtcc ggtgccctcc      900

tcctccagca cctaccac                                                    918


<210>  3713
<211>  912
<212>  DNA
<213>  Homo Sapiens

<400>  3713
ccaggggcag gacaggaagt acagacagag aacgtgacag tggctgaggg tggggtggct       60

gagatcacct gccgtctgca ccagtatgat gggtccatag ttgtcatcca gaacccagcc      120

cggcagaccc tcttcttcaa tggcacccgt gccttgaagg atgagcgttt ccagcttgag      180

gagttctccc cacgccgggt gcggatccgg ctctcagatg cccgcctgga ggacgagggg      240

ggctatttct gccagctcta cacagaagac acccaccacc agattgccac gctcacggta      300

ctagtggccc cagagaatcc tgtggtggag gtccgggagc aggcggtaga gggcggcgag      360

gtggagctca gctgcctcgt tccgcggtcc cgtccggctg ccaccctgcg ctggtaccgg      420

gaccgcaagg agctgaaagg agtgagcagc agccaggaaa atggcaaggt ctggagcgtg      480

gcaagcacag tacggtttcg tgtggaccgt aaggacgacg gtggtatcat catctgtgag      540

gcgcagaacc aggcgctgcc ctccggacac agcaagcaga cgcagtacgt gctggatgtg      600

cagtactccc ccacggcccg gattcatgcc tcccaagctg tggtgaggga gggagacacg      660

ctggtgttga cgtgtgctgt cacggggaac cccaggccaa accagatccg ctggaaccgc      720

gggaatgagt ctttgccgga gagggcggag gccgtgggag agacgctcac gctgccgggt      780

ctggtatccg cggataacgg cacctacact tgcgaggcgt ccaataagca cggccatgcg      840

agggcgctct acgtacttgt ggtctacgac cctggtgcgg tggtagaggc tcagacgtcg      900

gttccctatg cc                                                          912


<210>  3714
<211>  798
<212>  DNA
<213>  Homo Sapiens

<400>  3714
atgggtcaga aggaaaggag cacagcagat actctgccgg atctggagga atggaagtca       60

gcggcgggtc tgcgatggtg gcaaacagca gtggtggacg gttctgggtc tggtaatgaa      120

gtcatagaag gcccccaaaa tgcaagagtc ctgaagggct cccaggctcg cttcaactgc      180

accgtctccc agggctggaa gctcatcatg tgggctctca gtgacatggt ggtgctaagc      240

gtcaggccca tggagcccat catcaccaat gaccgcttca cctctcagag gtacgaccag      300

ggcgggaact tcacctcgga gatgatcatc cacaatgtgg agcccagtga ttcggggaac      360

atcagatgca gcctccagaa cagtcgcctg catggatctg cttaccttac cgtccaagtt      420

atgggagagc tgttcattcc cagtgttaat cttgtagtcg ctgagaatga accttgtgaa      480

gttacttgtc taccctcaca ctggacccgg ctcccggata tttcctggga gctcggtctc      540

ctggtcagcc attcaagcta ttattttgtt ccggagccca gcgaccttca aagtgcagtg      600

agcatcctgg ctctgacccc acagagcaat gggactttga cttgcgtggc tacctggaag      660

agcctgaagg cccgcaagtc tgcaactgta aatctcactg tgattcggtg tccccaagac      720

actggaggtg gtattaatat tccaggtgta ttatcaagtt taccgagttt aggtttttca      780

ttgcctactt ggggcaaa                                                    798


<210>  3715
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  3715
tgtactctct ctgtcacaca accgtggtac ctagaagtgg actacactca tgaggccgtc       60

accataaagt gtaccttctc cgcaaccgga tgcccttctg agcaaccaac atgcctgtgg      120

tttcgctacg gtgctcaccg gcctgagaac ctgtgcttgg acgggtgcaa aagtgaggca      180

gacaagttca cagtgaggga ggccctcaaa gaaaaccaag tttccctcac tgtaaacaga      240

gtgacttcaa atgacagtgc aatttacatc tgtggaatag cattccccag tgtgccggaa      300

gcgagagcta aacagacagg aggagggacc acactggtgg taagagaaat taagctgctc      360

agcaaggaac tgcggagc                                                    378


<210>  3716
<211>  1656
<212>  DNA
<213>  Homo Sapiens

<400>  3716
cgggaggtgc tggtccccga ggggcccttg taccgcgtgg ctggcacagc tgtctccatc       60

tcctgcaatg tgaccggcta tgagggccct gcccagcaga acttcgagtg gttcctgtat      120

aggcccgagg ccccagatac tgcactgggc attgtcagta ccaaggatac ccagttctcc      180

tatgctgtct tcaagtcccg agtggtggcg ggtgaggtgc aggtgcagcg cctacaaggt      240

gatgccgtgg tgctcaagat tgcccgcctg caggcccagg atgccggcat ttatgagtgc      300

cacaccccct ccactgatac ccgctacctg ggcagctaca gcggcaaggt ggagctgaga      360

gttcttccag atgtcctcca ggtgtctgct gcccccccag ggccccgagg ccgccaggcc      420

ccaacctcac ccccacgcat gacggtgcat gaggggcagg agctggcact gggctgcctg      480

gcgaggacaa gcacacagaa gcacacacac ctggcagtgt cctttgggcg atctgtgccc      540

gaggcaccag ttgggcggtc aactctgcag gaagtggtgg gaatccggtc agacttggcc      600

gtggaggctg gagctcccta tgctgagcga ttggctgcag gggagcttcg tctgggcaag      660

gaagggaccg atcggtaccg catggtagta gggggtgccc aggcagggga cgcaggcacc      720

taccactgca ctgccgctga gtggattcag gatcctgatg gcagctgggc ccagattgca      780

gagaaaaggg ccgtcctggc ccacgtggat gtgcagacgc tgtccagcca gctggcagtg      840

acagtggggc ctggtgaacg tcggatcggc ccaggggagc ccttggaact gctgtgcaat      900

gtgtcagggg cacttccccc agcaggccgt catgctgcat actctgtagg ttgggagatg      960

gcacctgcgg gggcacctgg gcccggccgc ctggtagccc agctggacac agagggtgtg     1020

ggcagcctgg gccctggcta tgagggccga cacattgcca tggagaaggt ggcatccaga     1080

acataccggc tacggctaga ggctgccagg cctggtgatg cgggcaccta ccgctgcctc     1140

gccaaagcct atgttcgagg gtctgggacc cggcttcgtg aagcagccag tgcccgttcc     1200

cggcctctcc ctgtacatgt gcgggaggaa ggtgtggtgc tggaggctgt ggcatggcta     1260

gcaggaggca cagtgtaccg cggggagact gcctccctgc tgtgcaacat ctctgtgcgg     1320

ggtggccccc caggactgcg gctggccgcc agctggtggg tggagcgacc agaggacgga     1380

gagctcagct ctgtccctgc ccagctggtg ggtggcgtag gccaggatgg tgtggcagag     1440

ctgggagtcc ggcctggagg aggccctgtc agcgtagagc tggtggggcc ccgaagccat     1500

cggctgagac tacacagctt ggggcccgag gatgaaggcg tgtaccactg tgcccccagc     1560

gcctgggtgc agcatgccga ctacagctgg taccaggcgg gcagtgcccg ctcagggcct     1620

gttacagtct acccctacat gcatgccctg gacacc                               1656


<210>  3717
<211>  2094
<212>  DNA
<213>  Homo Sapiens

<400>  3717
cgagggaagc ctgaggtggt atcggtggtg ggccgggctg aggagagtgt ggtgctgggc       60

tgtgacctgc tgcccccggc cggccggccc cccctgcatg tcatcgagtg gctgcgcttt      120

ggattcctgc ttcccatctt catccagttc ggcctctact ctccccgaat tgaccctgat      180

tacgtgggac gagtccggct gcagaagggg gcctctctcc agattgaggg tctccgggtg      240

gaagaccagg gctggtacga gtgccgcgtg ttcttcctgg accagcacat ccctgaagac      300

gattttgcta acggctcctg ggtgcatctg acagtcaatt caccccctca attccaggag      360

acacctcctg ctgtgttgga agtgcaggaa ctggagcctg tgaccctgcg ttgtgtggcc      420

cgtggcagcc ccctgcctca tgtgacgtgg aagctccgag gaaaggacct tggccagggc      480

cagggccagg tgcaagtgca gaacgggacg ctgcggatcc gccgggtaga gcgaggcagc      540

tctggggtct acacctgcca agcctccagc actgagggca gcgccaccca cgccacccag      600

ctgctagtgc taggaccccc agtcatcgtg gtgcccccca agaacagcac agtcaatgcc      660

tcccaggatg tttcattggc ctgccatgct gaggcatacc ctgctaacct cacctacagc      720

tggttccagg acaacatcaa tgtcttccac attagccgcc tgcagccccg ggtgcagatc      780

ctggtggacg ggagcctgcg gctgctggcc acccagcctg atgatgccgg ctgctacacc      840

tgtgtgccca gcaatggcct cctgcatcca ccctcagcct ctgcctacct cactgtgctc      900

tgcatgccgg gggtgatccg ctgcccggtt cgtgccaacc ccccactgct ctttgtcagc      960

tggaccaagg atggaaaggc cctgcagctg gacaagttcc ctggctggtc ccagggcaca     1020

gaaggctcac tgatcatcgc cctggggaac gaggatgccc tgggagaata ctcctgcacc     1080

ccctacaaca gtcttggtac cgccgggccc tctcctgtga cccgcgtgct gctcaaggct     1140

cccccagctt ttatagagcg gcccaaggaa gaatatttcc aagaagtagg gcgggagctg     1200

ctcatcccct gctccgccca aggggaccct cctcctgttg tctcttggac caaggtgggc     1260

cgggggctgc aaggccaggc ccaggtggac agcaacagca gcctcatcct gcgaccattg     1320

accaaggagg cccacgggca ctgggaatgc agtgccagca atgctgtggc ccgagtggcc     1380

acctccacga acgtctacgt gctgggcact agccctcatg ttgtcaccaa tgtgtccgtg     1440

gtggctttgc ccaagggtgc caatgtctcc tgggagcctg gctttgatgg tggttatctg     1500

cagagattca gtgtctggta caccccactg gccaagcgtc ctgaccgaat gcaccatgac     1560

tgggtgtcct tggcagtgcc tgtgggggct gctcacctcc tagtgccagg gctgcagccc     1620

cacacccagt accagttcag cgtgctagct cagaacaagc tggggagtgg tcccttcagc     1680

gaaatcgtct tgtctgctcc ggaagggctt cctaccacgc cagctgcacc cgggcttccc     1740

ccaacagaga taccgcctcc cctgtcccct ccgcggggtc tggtggcagt gaggacaccc     1800

cggggggtac tcctgcattg ggatccccca gagctggtcc ctaagagact ggatggctac     1860

gtcttggaag gccggcaagg ctcccagggc tgggaggtgc tggacccggc tgtggcaggc     1920

acagaaacag agctgctggt gccaggcctc atcaaggatg ttctctacga gttccgcctc     1980

gtggccttcg cgggcagctt cgtcagcgac cccagcaaca cggccaacgt ctccacttcc     2040

ggtctggagg tctacccttc gcgcacgcag ctgccgggcc tcctgcctca gccc           2094


<210>  3718
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  3718
agcccaggcc agggcaccca gtctgagaac agctgcaccc acttcccagg caacctgcct       60

aacatgcttc gagatctccg agatgccttc agcagagtga agactttctt tcaaatgaag      120

gatcagctgg acaacttgtt gttaaaggag tccttgctgg aggactttaa gggttacctg      180

ggttgccaag ccttgtctga gatgatccag ttttacctgg aggaggtgat gccccaagct      240

gagaaccaag acccagacat caaggcgcat gtgaactccc tgggggagaa cctgaagacc      300

ctcaggctga ggctacggcg ctgtcatcga tttcttccct gtgaaaacaa gagcaaggcc      360

gtggagcagg tgaagaatgc ctttaataag ctccaagaga aaggcatcta caaagccatg      420

agtgagtttg acatcttcat caactacata gaagcctaca tgacaatgaa gatacgaaac      480


<210>  3719
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  3719
catgggacag agctgcccag ccctccgtct gtgtggtttg aagcagaatt tttccaccac       60

atcctccact ggacacccat cccaaatcag tctgaaagta cctgctatga agtggcactc      120

ctgaggtatg gaatagagtc ctggaactcc atctccaact gtagccagac cctgtcctat      180

gaccttaccg cagtgacctt ggacctgtac cacagcaatg gctaccgggc cagagtgcgg      240

gctgtggacg gcagccggca ctccaactgg accgtcacca acacccgctt ctctgtggat      300

gaagtgactc tgacagttgg cagtgtgaac ctagagatcc acaatggctt catcctcggg      360

aagattcagc tacccaggcc caagatggcc cccgcaaatg acacatatga aagcatcttc      420

agtcacttcc gagagtatga gattgccatt cgcaaggtgc cgggaaactt cacgttcaca      480

cacaagaaag taaaacatga aaacttcagc ctcctaacct ctggagaagt gggagagttc      540

tgtgtccagg tgaaaccatc tgtcgcttcc cgaagtaaca aggggatgtg gtctaaagag      600

gagtgcatct ccctcaccag gcagtatttc accgtgacca ac                         642


<210>  3720
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  3720
atggtaccac ctcccgaaaa tgtcagaatg aattctgtta atttcaagaa cattctacag       60

tgggagtcac ctgcttttgc caaagggaac ctgactttca cagctcagta cctaagttat      120

aggatattcc aagataaatg catgaatact accttgacgg aatgtgattt ctcaagtctt      180

tccaagtatg gtgaccacac cttgagagtc agggctgaat ttgcagatga gcattcagac      240

tgggtaaaca tcaccttctg tcctgtggat gacaccatta ttggaccccc tggaatgcaa      300

gtagaagtac ttgctgattc tttacatatg cgtttcttag cccctaaaat tgagaatgaa      360

tacgaaactt ggactatgaa gaatgtgtat aactcatgga cttataatgt gcaatactgg      420

aaaaacggta ctgatgaaaa gtttcaaatt actccccagt atgactttga ggtcctcaga      480

aacctggagc catggacaac ttattgtgtt caagttcgag ggtttcttcc tgatcggaac      540

aaagctgggg aatggagtga gcctgtctgt gagcaaacaa cccatgacga aacggtcccc      600

tcc                                                                    603


<210>  3721
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  3721
cctgggccac cacctggccc ccctcgagtt tccccagacc ctcgggccga gctggacagc       60

accgtgctcc tgacccgctc tctcctggcg gacacgcggc agctggctgc acagctgagg      120

gacaaattcc cagctgacgg ggaccacaac ctggattccc tgcccaccct ggccatgagt      180

gcgggggcac tgggagctct acagctccca ggtgtgctga caaggctgcg agcggaccta      240

ctgtcctacc tgcggcacgt gcagtggctg cgccgggcag gtggctcttc cctgaagacc      300

ctggagcccg agctgggcac cctgcaggcc cgactggacc ggctgctgcg ccggctgcag      360

ctcctgatgt cccgcctggc cctgccccag ccacccccgg acccgccggc gcccccgctg      420

gcgcccccct cctcagcctg ggggggcatc agggccgccc acgccatcct gggggggctg      480

cacctgacac ttgactgggc cgtgagggga ctgctgctgc tgaagactcg gctg            534


<210>  3722
<211>  1041
<212>  DNA
<213>  Homo Sapiens

<400>  3722
tccccctgcc cccaggcctg gggcccccca ggggtccagt atgggcagcc aggcaggtcc       60

gtgaagctgt gttgtcctgg agtgactgcc ggggacccag tgtcctggtt tcgggatggg      120

gagccaaagc tgctccaggg acctgactct gggctagggc atgaactggt cctggcccag      180

gcagacagca ctgatgaggg cacctacatc tgccagaccc tggatggtgc acttgggggc      240

acagtgaccc tgcagctggg ctaccctcca gcccgccctg ttgtctcctg ccaagcagcc      300

gactatgaga acttctcttg cacttggagt cccagccaga tcagcggttt acccacccgc      360

tacctcacct cctacaggaa gaagacagtc ctaggagctg atagccagag gaggagtcca      420

tccacagggc cctggccatg cccacaggat cccctagggg ctgcccgctg tgttgtccac      480

ggggctgagt tctggagcca gtaccggatt aatgtgactg aggtgaaccc actgggtgcc      540

agcacacgcc tgctggatgt gagcttgcag agcatcttgc gccctgaccc accccagggc      600

ctgcgggtag agtcagtacc aggttacccc cgacgcctgc gagccagctg gacataccct      660

gcctcctggc cgtgccagcc ccacttcctg ctcaagttcc gtttgcagta ccgtccggcg      720

cagcatccag cctggtccac ggtggagcca gctggactgg aggaggtgat cacagatgct      780

gtggctgggc tgccccatgc tgtacgagtc agtgcccggg actttctaga tgctggcacc      840

tggagcacct ggagcccgga ggcctgggga actccgagca ctgggaccat accaaaggag      900

ataccagcat ggggccagct acacacgcag ccagaggtgg agcctcaggt ggacagccct      960

gctcctccaa ggccctccct ccaaccacac cctcggctac ttgatcacag ggactctgtg     1020

gagcaggtag ctgtgctggc g                                               1041


<210>  3723
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  3723
agaaacctcc ccgtggccac tccagaccca ggaatgttcc catgccttca ccactcccaa       60

aacctgctga gggccgtcag caacatgctc cagaaggcca gacaaactct agaattttac      120

ccttgcactt ctgaagagat tgatcatgaa gatatcacaa aagataaaac cagcacagtg      180

gaggcctgtt taccattgga attaaccaag aatgagagtt gcctaaattc cagagagacc      240

tctttcataa ctaatgggag ttgcctggcc tccagaaaga cctcttttat gatggccctg      300

tgccttagta gtatttatga agacttgaag atgtaccagg tggagttcaa gaccatgaat      360

gcaaagcttc tgatggatcc taagaggcag atctttctag atcaaaacat gctggcagtt      420

attgatgagc tgatgcaggc cctgaatttc aacagtgaga ctgtgccaca aaaatcctcc      480

cttgaagaac cggattttta taaaactaaa atcaagctct gcatacttct tcatgctttc      540

agaattcggg cagtgactat tgatagagtg atgagctatc tgaatgcttc c               591


<210>  3724
<211>  918
<212>  DNA
<213>  Homo Sapiens

<400>  3724
atatgggaac tgaagaaaga tgtttatgtc gtagaattgg attggtatcc ggatgcccct       60

ggagaaatgg tggtcctcac ctgtgacacc cctgaagaag atggtatcac ctggaccttg      120

gaccagagca gtgaggtctt aggctctggc aaaaccctga ccatccaagt caaagagttt      180

ggagatgctg gccagtacac ctgtcacaaa ggaggcgagg ttctaagcca ttcgctcctg      240

ctgcttcaca aaaaggaaga tggaatttgg tccactgata ttttaaagga ccagaaagaa      300

cccaaaaata agacctttct aagatgcgag gccaagaatt attctggacg tttcacctgc      360

tggtggctga cgacaatcag tactgatttg acattcagtg tcaaaagcag cagaggctct      420

tctgaccccc aaggggtgac gtgcggagct gctacactct ctgtagagag agtcagaggg      480

gacaacaagg agtatgagta ctcagtggag tgccaggagg acagtgcctg cccagctgct      540

gaggagagtc tgcccattga ggtcatggtg gatgccgttc acaagctcaa gtatgaaaac      600

tacaccagca gcttcttcat cagggacatc atcaaacctg acccacccaa gaacttgcag      660

ctgaagccat taaagaattc tcggcaggtg gaggtcagct gggagtaccc tgacacctgg      720

agtactccac attcctactt ctccctgaca ttctgcgttc aggtccaggg caagagcaag      780

agagaaaaga aagatagagt cttcacggac aagacctcag ccacggtcat ctgccgcaaa      840

aatgccagca ttagcgtgcg ggcccaggac cgctactata gctcatcttg gagcgaatgg      900

gcatctgtgc cctgcagt                                                    918


<210>  3725
<211>  1566
<212>  DNA
<213>  Homo Sapiens

<400>  3725
tgcagaacca gtgagtgctg ttttcaggac ccgccatatc cggatgcaga ctcaggctcg       60

gcctcgggcc ctagggacct gagatgctat cggatatcca gtgatcgtta cgagtgctcc      120

tggcagtatg agggtcccac agctggggtc agccacttcc tgcggtgttg ccttagctcc      180

gggcgctgct gctacttcgc cgccggctca gccaccaggc tgcagttctc cgaccaggct      240

ggggtgtctg tgctgtacac tgtcacactc tgggtggaat cctgggccag gaaccagaca      300

gagaagtctc ctgaggtgac cctgcagctc tacaactcag ttaaatatga gcctcctctg      360

ggagacatca aggtgtccaa gttggccggg cagctgcgta tggagtggga gaccccggat      420

aaccaggttg gtgctgaggt gcagttccgg caccggacac ccagcagccc atggaagttg      480

ggcgactgcg gacctcagga tgatgatact gagtcctgcc tctgccccct ggagatgaat      540

gtggcccagg aattccagct ccgacgacgg cagttgggga gccaaggaag ttcctggagc      600

aagtggagca gccccgtgtg cgttccccct gaaaaccccc cacagcctca ggtgagattc      660

tcggtggagc agctgggcca ggatgggagg aggcggctga ccctgaaaga gcagccaacc      720

cagctggagc ttccagaagg ctgtcaaggg ctggcgcctg gcacggaggt cacttaccga      780

ctacagctcc acatgctgtc ctgcccgtgt aaggccaagg ccaccgggac cctgcacctg      840

gggaagatgc cctatctctc gggtgctgcc tacaacgtgg ctgtcatctc ctcgaaccaa      900

tttggtcctg gcctgaacca gacgtggcac attcctgccg acacccacac agaaccagtg      960

gctctgaata tcagcgtcgg aaccaacggg accaccatgt attggccagc ccgggctcag     1020

agcatgacgt attgcattga atggcagcct gtgggccagg acgggggcct tgccacctgc     1080

agcctgactg cgccgcaaga cccggatccg gctggaatgg caacctacag ctggagtcga     1140

gggtctgggg caatggggca ggaaaagtgt tactacatta ccatctttgc ctctgcgcac     1200

cccgagaagc tcaccttgtg gtctacggtc ctgtccacct accactttgg gggcaatgcc     1260

tcagcagctg ggacaccgca ccacgtctcg gtgaagaatc atagcttgga ctctgtgtct     1320

gtggactggg caccatccct gctgagcacc tgtcccggcg tcctaaagga gtatgttgtc     1380

cgctgccgag atgaagacag caaacaggtg tcagagcatc ccgtgcagcc cacagagacc     1440

caagttaccc tcagtggcct gcgggctggt gtagcctaca cggtgcaggt gcgagcagac     1500

acagcgtggc tgaggggtgt ctggagccag ccccagcgct tcagcatcga agtgcaggtt     1560

tctgat                                                                1566


<210>  3726
<211>  1797
<212>  DNA
<213>  Homo Sapiens

<400>  3726
aaaatagatg cgtgcaagag aggcgatgtg actgtgaagc cttcccatgt aattttactt       60

ggatccactg tcaatattac atgctctttg aagcccagac aaggctgctt tcactattcc      120

agacgtaaca agttaatcct gtacaagttt gacagaagaa tcaattttca ccatggccac      180

tccctcaatt ctcaagtcac aggtcttccc cttggtacaa ccttgtttgt ctgcaaactg      240

gcctgtatca atagtgatga aattcaaata tgtggagcag agatcttcgt tggtgttgct      300

ccagaacagc ctcaaaattt atcctgcata cagaagggag aacaggggac tgtggcctgc      360

acctgggaaa gaggacgaga cacccactta tacactgagt atactctaca gctaagtgga      420

ccaaaaaatt taacctggca gaagcaatgt aaagacattt attgtgacta tttggacttt      480

ggaatcaacc tcacccctga atcacctgaa tccaatttca cagccaaggt tactgctgtc      540

aatagtcttg gaagctcctc ttcacttcca tccacattca cattcttgga catagtgagg      600

cctcttcctc cgtgggacat tagaatcaaa tttcaaaagg cttccgtgag cagatgtacc      660

ctttattgga gagatgaggg actggtactg cttaatcgac tcagatatcg gcccagtaac      720

agcaggctct ggaatatggt taatgttaca aaggccaaag gaagacatga tttgctggat      780

ctgaaaccat ttacagaata tgaatttcag atttcctcta agctacatct ttataaggga      840

agttggagtg attggagtga atcattgaga gcacaaacac cagaagaaga gcctactggg      900

atgttagatg tctggtacat gaaacggcac attgactaca gtagacaaca gatttctctt      960

ttctggaaga atctgagtgt ctcagaggca agaggaaaaa ttctccacta tcaggtgacc     1020

ttgcaggagc tgacaggagg gaaagccatg acacagaaca tcacaggaca cacctcctgg     1080

accacagtca ttcctagaac cggaaattgg gctgtggctg tgtctgcagc aaattcaaaa     1140

ggcagttctc tgcccactcg tattaacata atgaacctgt gtgaggcagg gttgctggct     1200

cctcgccacg tctctgcaaa ctcagagggc atggacaaca ttctggtgac ttggcagcct     1260

cccaggaaag atccctctgc tgttcaggag tacgtggtgg aatggagaga gctccatcca     1320

gggggtgaca cacaggtccc tctaaactgg ctacggagtc gaccctacaa tgtgtctgct     1380

ctgatttcag agaacataaa atcctacatc tgttatgaaa tccgtgtgta tgcactctca     1440

ggggatcaag gaggatgcag ctccatcctg ggtaactcta agcacaaagc accactgagt     1500

ggcccccaca ttaatgccat cacagaggaa aaggggagca ttttaatttc atggaacagc     1560

attccagtcc aggagcaaat gggctgcctc ctccattata ggatatactg gaaggaacgg     1620

gactccaact cccagcctca gctctgtgaa attccctaca gagtctccca aaattcacat     1680

ccaataaaca gcctgcagcc ccgagtgaca tatgtcctgt ggatgacagc tctgacagct     1740

gctggtgaaa gttcccacgg aaatgagagg gaattttgtc tgcaaggtaa agccaat        1797


<210>  3727
<211>  366
<212>  DNA
<213>  Homo Sapiens

<400>  3727
ctcacttgcc ttggcggctt tgcctcccca ggccctgtgc ctccctctac agccctcagg       60

gagctcattg aggagctggt caacatcacc cagaaccaga aggctccgct ctgcaatggc      120

agcatggtat ggagcatcaa cctgacagct ggcatgtact gtgcagccct ggaatccctg      180

atcaacgtgt caggctgcag tgccatcgag aagacccaga ggatgctgag cggattctgc      240

ccgcacaagg tctcagctgg gcagttttcc agcttgcatg tccgagacac caaaatcgag      300

gtggcccagt ttgtaaagga cctgctctta catttaaaga aactttttcg cgagggacag      360

ttcaac                                                                 366


<210>  3728
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  3728
gggggcgggg gcgccgcgcc tacggaaact cagccacctg tgacaaattt gagtgtctct       60

gttgaaaacc tctgcacagt aatatggaca tggaatccac ccgagggagc cagctcaaat      120

tgtagtctat ggtattttag tcattttggc gacaaacaag ataagaaaat agctccggaa      180

actcgtcgtt caatagaagt acccctgaat gagaggattt gtctgcaagt ggggtcccag      240

tgtagcacca atgagagtga gaagcctagc attttggttg aaaaatgcat ctcaccccca      300

gaaggtgatc ctgagtctgc tgtgactgag cttcaatgca tttggcacaa cctgagctac      360

atgaagtgtt cttggctccc tggaaggaat accagtcccg acactaacta tactctctac      420

tattggcaca gaagcctgga aaaaattcat caatgtgaaa acatctttag agaaggccaa      480

tactttggtt gttcctttga tctgaccaaa gtgaaggatt ccagttttga acaacacagt      540

gtccaaataa tggtcaagga taatgcagga aaaattaaac catccttcaa tatagtgcct      600

ttaacttccc gtgtgaaacc tgatcctcca catattaaaa acctctcctt ccacaatgat      660

gacctatatg tgcaatggga gaatccacag aattttatta gcagatgcct attttatgaa      720

gtagaagtca ataacagcca aactgagaca cataatgttt tctacgtcca agaggctaaa      780

tgtgagaatc cagaatttga gagaaatgtg gagaatacat cttgtttcat ggtccctggt      840

gttcttcctg atactttgaa cacagtcaga ataagagtca aaacaaataa gttatgctat      900

gaggatgaca aactctggag taattggagc caagaaatga gtataggtaa gaagcgcaat      960

tccaca                                                                 966


<210>  3729
<211>  951
<212>  DNA
<213>  Homo Sapiens

<400>  3729
gacaccgaga taaaagttaa ccctcctcag gattttgaga tagtggatcc cggatactta       60

ggttatctct atttgcaatg gcaaccccca ctgtctctgg atcattttaa ggaatgcaca      120

gtggaatatg aactaaaata ccgaaacatt ggtagtgaaa catggaagac catcattact      180

aagaatctac attacaaaga tgggtttgat cttaacaagg gcattgaagc gaagatacac      240

acgcttttac catggcaatg cacaaatgga tcagaagttc aaagttcctg ggcagaaact      300

acttattgga tatcaccaca aggaattcca gaaactaaag ttcaggatat ggattgcgta      360

tattacaatt ggcaatattt actctgttct tggaaacctg gcataggtgt acttcttgat      420

accaattaca acttgtttta ctggtatgag ggcttggatc atgcattaca gtgtgttgat      480

tacatcaagg ctgatggaca aaatatagga tgcagatttc cctatttgga ggcatcagac      540

tataaagatt tctatatttg tgttaatgga tcatcagaga acaagcctat cagatccagt      600

tatttcactt ttcagcttca aaatatagtt aaacctttgc cgccagtcta tcttactttt      660

actcgggaga gttcatgtga aattaagctg aaatggagca tacctttggg acctattcca      720

gcaaggtgtt ttgattatga aattgagatc agagaagatg atactacctt ggtgactgct      780

acagttgaaa atgaaacata caccttgaaa acaacaaatg aaacccgaca attatgcttt      840

gtagtaagaa gcaaagtgaa tatttattgc tcagatgacg gaatttggag tgagtggagt      900

gataaacaat gctgggaagg tgaagaccta tcgaagaaaa ctttgctacg t               951


<210>  3730
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  3730
aactgggtga atgtaataag tgatttgaaa aaaattgaag atcttattca atctatgcat       60

attgatgcta ctttatatac ggaaagtgat gttcacccca gttgcaaagt aacagcaatg      120

aagtgctttc tcttggagtt acaagttatt tcacttgagt ccggagatgc aagtattcat      180

gatacagtag aaaatctgat catcctagca aacaacagtt tgtcttctaa tgggaatgta      240

acagaatctg gatgcaaaga atgtgaggaa ctggaggaaa aaaatattaa agaatttttg      300

cagagttttg tacatattgt ccaaatgttc atcaacactt ct                         342


<210>  3731
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3731
atcacgtgcc ctccccccat gtccgtggaa cacgcagaca tctgggtcaa gagctacagc       60

ttgtactcca gggagcggta catttgtaac tctggtttca agcgtaaagc cggcacgtcc      120

agcctgacgg agtgcgtgtt gaacaaggcc acgaatgtcg cccactggac aacccccagt      180

ctcaaatgca ttagagaccc tgccctggtt caccaaaggc cagcgccacc ctccacagta      240

acgacggcag gggtgacccc acagccagag agcctctccc cttctggaaa agagcccgca      300

gcttcatctc ccagctcaaa caacacagcg gccacaacag cagctattgt cccgggctcc      360

cagctgatgc cttcaaaatc accttccaca ggaaccacag agataagcag tcatgagtcc      420

tcccacggca ccccctctca gacaacagcc aagacctggg aactcacagc atccgcctcc      480

caccagccgc caggtgtgta tccacagggc cacagcgaca ccact                      525


<210>  3732
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3732
tctgcagcct cagcctctgc agccagtgat gtttctgtag aatctacaga ggccacagtc       60

tgcacggtga cactggagaa gatgtcggca gggctgggct tcagcctgga aggagggaag      120

ggctccctac acggagacaa gcctctcacc attaacagga ttttcaaagg agcagcctca      180

gaacaaagtg agacagtcca gcctggagat gaaatcttgc agctgggtgg cactgccatg      240

cagggcctca cacggtttga agcctggaac atcatcaagg cactgcctga tggacctgtc      300

acgattgtca tcaggagaaa aagcctccag tccaaggaaa ccacagctgc tggagactcc      360


<210>  3733
<211>  396
<212>  DNA
<213>  Homo Sapiens

<400>  3733
ggaatcacaa tcccacgaaa tccaggatgc ccaaattctg aggacaagaa cttcccccgg       60

actgtgatgg tcaacctgaa catccataac cggaatacca ataccaatcc caaaaggtcc      120

tcagattact acaaccgatc cacctcacct tggaatctcc accgcaatga ggaccctgag      180

agatatccct ctgtgatctg ggaggcaaag tgccgccact tgggctgcat caacgctgat      240

gggaacgtgg actaccacat gaactctgtc cccatccagc aagagatcct ggtcctgcgc      300

agggagcctc cacactgccc caactccttc cggctggaga agatactggt gtccgtgggc      360

tgcacctgtg tcaccccgat tgtccaccat gtggcc                                396


<210>  3734
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  3734
cagcccagga gccccaaaag caagaggaag gggcaagggc ggcctgggcc cctggcccct       60

ggccctcacc aggtgccact ggacctggtg tcacggatga aaccgtatgc ccgcatggag      120

gagtatgaga ggaacatcga ggagatggtg gcccagctga ggaacagctc agagctggcc      180

cagagaaagt gtgaggtcaa cttgcagctg tggatgtcca acaagaggag cctgtctccc      240

tggggctaca gcatcaacca cgaccccagc cgtatccccg tggacctgcc ggaggcacgg      300

tgcctgtgtc tgggctgtgt gaaccccttc accatgcagg aggaccgcag catggtgagc      360

gtgccggtgt tcagccaggt tcctgtgcgc cgccgcctct gcccgccacc gccccgcaca      420

gggccttgcc gccagcgcgc agtcatggag accatcgctg tgggctgcac ctgcatcttc      480


<210>  3735
<211>  825
<212>  DNA
<213>  Homo Sapiens

<400>  3735
cgagagccga ccgttcaatg tggctctgaa actgggccat ctccagagtg gatgctacaa       60

catgatctaa tcccgggaga cttgagggac ctccgagtag aacctgttac aactagtgtt      120

gcaacagggg actattcaat tttgatgaat gtaagctggg tactccgggc agatgccagc      180

atccgcttgt tgaaggccac caagatttgt gtgacgggca aaagcaactt ccagtcctac      240

agctgtgtga ggtgcaatta cacagaggcc ttccagactc agaccagacc ctctggtggt      300

aaatggacat tttcctacat cggcttccct gtagagctga acacagtcta tttcattggg      360

gcccataata ttcctaatgc aaatatgaat gaagatggcc cttccatgtc tgtgaatttc      420

acctcaccag gctgcctaga ccacataatg aaatataaaa aaaagtgtgt caaggccgga      480

agcctgtggg atccgaacat cactgcttgt aagaagaatg aggagacagt agaagtgaac      540

ttcacaacca ctcccctggg aaacagatac atggctctta tccaacacag cactatcatc      600

gggttttctc aggtgtttga gccacaccag aagaaacaaa cgcgagcttc agtggtgatt      660

ccagtgactg gggatagtga aggtgctacg gtgcagctga ctccatattt tcctacttgt      720

ggcagcgact gcatccgaca taaaggaaca gttgtgctct gcccacaaac aggcgtccct      780

ttccctctgg ataacaacaa aagcaagccg ggaggctggc tgcct                      825


<210>  3736
<211>  537
<212>  DNA
<213>  Homo Sapiens

<400>  3736
caccatgacc cctccctcag ggggcacccc cacagtcacg gtaccccaca ctgctactcg       60

gctgaggaac tgcccctcgg ccaggccccc ccacacctgc tggctcgagg tgccaagtgg      120

gggcaggctt tgcctgtagc cctggtgtcc agcctggagg cagcaagcca cagggggagg      180

cacgagaggc cctcagctac gacccagtgc ccggtgctgc ggccggagga ggtgttggag      240

gcagacaccc accagcgctc catctcaccc tggagatacc gtgtggacac ggatgaggac      300

cgctatccac agaagctggc cttcgccgag tgcctgtgca gaggctgtat cgatgcacgg      360

acgggccgcg agacagctgc gctcaactcc gtgcggctgc tccagagcct gctggtgctg      420

cgccgccggc cctgctcccg cgacggctcg gggctcccca cacctggggc ctttgccttc      480

cacaccgagt tcatccacgt ccccgtcggc tgcacctgcg tgctgccccg ttcagtg         537


<210>  3737
<211>  561
<212>  DNA
<213>  Homo Sapiens

<400>  3737
gcgggcgccc cgagggcggg caggcgcccc gcgcggccgc ggggctgcgc ggaccggccg       60

gaggagctac tggagcagct gtacgggcgc ctggcggccg gcgtgctcag tgccttccac      120

cacacgctgc agctggggcc gcgtgagcag gcgcgcaacg cgagctgccc ggcagggggc      180

aggcccgccg accgccgctt ccggccgccc accaacctgc gcagcgtgtc gccctgggcc      240

tacagaatct cctacgaccc ggcgaggtac cccaggtacc tgcctgaagc ctactgcctg      300

tgccggggct gcctgaccgg gctgttcggc gaggaggacg tgcgcttccg cagcgcccct      360

gtctacatgc ccaccgtcgt cctgcgccgc acccccgcct gcgccggcgg ccgttccgtc      420

tacaccgagg cctacgtcac catccccgtg ggctgcacct gcgtccccga gccggagaag      480

gacgcagaca gcatcaactc cagcatcgac aaacagggcg ccaagctcct gctgggcccc      540

aacgacgcgc ccgctggccc c                                                561


<210>  3738
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3738
cggaaaatcc ccaaagtagg acatactttt ttccaaaagc ctgagagttg cccgcctgtg       60

ccaggaggta gtatgaagct tgacattggc atcatcaatg aaaaccagcg cgtttccatg      120

tcacgtaaca tcgagagccg ctccacctcc ccctggaatt acactgtcac ttgggacccc      180

aaccggtacc cctcggaagt tgtacaggcc cagtgtagga acttgggctg catcaatgct      240

caaggaaagg aagacatctc catgaattcc gttcccatcc agcaagagac cctggtcgtc      300

cggaggaagc accaaggctg ctctgtttct ttccagttgg agaaggtgct ggtgactgtt      360

ggctgcacct gcgtcacccc tgtcatccac cgtgtgcag                             399


<210>  3739
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  3739
ctgcgactcc tggaccaccg ggcgctggtc tgctcccagc cggggctaaa ctgcacggtc       60

aagaatagta cctgcctgga tgacagctgg attcaccctc gaaacctgac cccctcctcc      120

ccaaaggacc tgcagatcca gctgcacttt gcccacaccc aacaaggaga cctgttcccc      180

gtggctcaca tcgaatggac actgcagaca gacgccagca tcctgtacct cgagggtgca      240

gagttatctg tcctgcagct gaacaccaat gaacgtttgt gcgtcaggtt tgagtttctg      300

tccaaactga ggcatcacca caggcggtgg cgttttacct tcagccactt tgtggttgac      360

cctgaccagg aatatgaggt gaccgttcac cacctgccca agcccatccc tgatggggac      420

ccaaaccacc agtccaagaa tttccttgtg cctgactgtg agcacgccag gatgaaggta      480

accacgccat gcatgagctc aggcagcctg tgggacccca acatcaccgt ggagaccctg      540

gaggcccacc agctgcgtgt gagcttcacc ctgtggaacg aatctaccca ttaccagatc      600

ctgctgacca gttttccgca catggagaac cacagttgct ttgagcacat gcaccacata      660

cctgcgccca gaccagaaga gttccaccag cgatccaacg tcacactcac tctacgcaac      720

cttaaagggt gctgtcgcca ccaagtgcag atccagccct tcttcagcag ctgcctcaat      780

gactgcctca gacactccgc gactgtttcc tgcccagaaa tgccagacac tccagaacca      840

attccggact acatgcccct gtgg                                             864


<210>  3740
<211>  1296
<212>  DNA
<213>  Homo Sapiens

<400>  3740
ctggagaggc ttgtggggcc tcaggacgct acccactgct ctccgggcct ctcctgccgc       60

ctctgggaca gtgacatact ctgcctgcct ggggacatcg tgcctgctcc gggccccgtg      120

ctggcgccta cgcacctgca gacagagctg gtgctgaggt gccagaagga gaccgactgt      180

gacctctgtc tgcgtgtggc tgtccacttg gccgtgcatg ggcactggga agagcctgaa      240

gatgaggaaa agtttggagg agcagctgac tcaggggtgg aggagcctag gaatgcctct      300

ctccaggccc aagtcgtgct ctccttccag gcctacccta ctgcccgctg cgtcctgctg      360

gaggtgcaag tgcctgctgc ccttgtgcag tttggtcagt ctgtgggctc tgtggtatat      420

gactgcttcg aggctgccct agggagtgag gtacgaatct ggtcctatac tcagcccagg      480

tacgagaagg aactcaacca cacacagcag ctgcctgccc tgccctggct caacgtgtca      540

gcagatggtg acaacgtgca tctggttctg aatgtctctg aggagcagca cttcggcctc      600

tccctgtact ggaatcaggt ccagggcccc ccaaaacccc ggtggcacaa aaacctgact      660

ggaccgcaga tcattacctt gaaccacaca gacctggttc cctgcctctg tattcaggtg      720

tggcctctgg aacctgactc cgttaggacg aacatctgcc ccttcaggga ggacccccgc      780

gcacaccaga acctctggca agccgcccga ctgcgactgc tgaccctgca gagctggctg      840

ctggacgcac cgtgctcgct gcccgcagaa gcggcactgt gctggcgggc tccgggtggg      900

gacccctgcc agccactggt cccaccgctt tcctgggaga acgtcactgt ggacaaggtt      960

ctcgagttcc cattgctgaa aggccaccct aacctctgtg ttcaggtgaa cagctcggag     1020

aagctgcagc tgcaggagtg cttgtgggct gactccctgg ggcctctcaa agacgatgtg     1080

ctactgttgg agacacgagg cccccaggac aacagatccc tctgtgcctt ggaacccagt     1140

ggctgtactt cactacccag caaagcctcc acgagggcag ctcgccttgg agagtactta     1200

ctacaagacc tgcagtcagg ccagtgtctg cagctatggg acgatgactt gggagcgcta     1260

tgggcctgcc ccatggacaa atacatccac aagcgc                               1296


<210>  3741
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  3741
atggaatctc aacctttcct gaatatgaaa tttgaaacgg attatttcgt aaaggttgtc       60

ccttttcctt ccattaaaaa cgaaagcaat taccaccctt tcttctttag aacccgagcc      120

tgtgacctgt tgttacagcc ggacaatcta gcttgtaaac ccttctggaa gcctcggaac      180

ctgaacatca gccagcatgg ctcggacatg caggtgtcct tcgaccacgc accgcacaac      240

ttcggcttcc gtttcttcta tcttcactac aagctcaagc acgaaggacc tttcaagcga      300

aagacctgta agcaggagca aactacagag acgaccagct gcctccttca aaatgtttct      360

ccaggggatt atataattga gctggtggat gacactaaca caacaagaaa agtgatgcat      420

tatgccttaa agccagtgca ctccccgtgg gccgggccca tcaga                      465


<210>  3742
<211>  1293
<212>  DNA
<213>  Homo Sapiens

<400>  3742
gctgggattg gctttcgcca cctgccccac tggaacaccc gctgtcctct ggcctcccac       60

acggatgaca gtttcactgg aagttctgcc tatatccctt gccgcacctg gtgggccctc      120

ttctccacaa agccttggtg tgtgcgagtc tggcactgtt cccgctgttt gtgccagcat      180

ctgctgtcag gtggctcagg tcttcaacgg ggcctcttcc acctcctggt gcagaaatcc      240

aaaaagtctt ccacattcaa gttctatagg agacacaaga tgccagcacc tgctcagagg      300

aagctgctgc ctcgtcgtca cctgtctgag aagagccatc acatttccat cccctcccca      360

gacatctccc acaagggact tcgctctaaa aggacccaac cttcggatcc agagacatgg      420

gaaagtcttc ccagattgga ctcacaaagg catggaggac ccgagttctc ctttgatttg      480

ctgcctgagg cccgggctat tcgggtgacc atatcttcag gccctgaggt cagcgtgcgt      540

ctttgtcacc agtgggcact ggagtgtgaa gagctgagca gtccctatga tgtccagaaa      600

attgtgtctg ggggccacac tgtagagctg ccttatgaat tccttctgcc ctgtctgtgc      660

atagaggcat cctacctgca agaggacact gtgaggcgca aaaaatgtcc cttccagagc      720

tggccagaag cctatggctc ggacttctgg aagtcagtgc acttcactga ctacagccag      780

cacactcaga tggtcatggc cctgacactc cgctgcccac tgaagctgga agctgccctc      840

tgccagaggc acgactggca taccctttgc aaagacctcc cgaatgccac agctcgagag      900

tcagatgggt ggtatgtttt ggagaaggtg gacctgcacc cccagctctg cttcaagttc      960

tcttttggaa acagcagcca tgttgaatgc ccccaccaga ctgggtctct cacatcctgg     1020

aatgtaagca tggataccca agcccagcag ctgattcttc acttctcctc aagaatgcat     1080

gccaccttca gtgctgcctg gagcctccca ggcttggggc aggacacttt ggtgcccccc     1140

gtgtacactg tcagccaggc ccggggctca agcccagtgt cactagacct catcattccc     1200

ttcctgaggc cagggtgctg tgtcctggtg tggcggtcag atgtccagtt tgcctggaag     1260

cacctcttgt gtccggatgt ctcttacaga cac                                  1293


<210>  3743
<211>  471
<212>  DNA
<213>  Homo Sapiens

<400>  3743
tactttggca agcttgaatc taaattatca gtcataagaa atttgaatga ccaagttctc       60

ttcattgacc aaggaaatcg gcctctattt gaagatatga ctgattctga ctgtagagat      120

aatgcacccc ggaccatatt tattataagt atgtataaag atagccagcc tagaggtatg      180

gctgtaacta tctctgtgaa gtgtgagaaa atttcaactc tctcctgtga gaacaaaatt      240

atttccttta aggaaatgaa tcctcctgat aacatcaagg atacaaaaag tgacatcata      300

ttctttcaga gaagtgtccc aggacatgat aataagatgc aatttgaatc ttcatcatac      360

gaaggatact ttctagcttg tgaaaaagag agagaccttt ttaaactcat tttgaaaaaa      420

gaggatgaat tgggggatag atctataatg ttcactgttc aaaacgaaga c               471


<210>  3744
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  3744
acacctgtct cgcagaccac cacagctgcc actgcctcag ttagaagcac aaaggacccc       60

tgcccctccc agcccccagt gttcccagca gctaagcagt gtccagcatt ggaagtgacc      120

tggccagagg tggaagtgcc actgaatgga acgctgagct tatcctgtgt ggcctgcagc      180

cgcttcccca acttcagcat cctctactgg ctgggcaatg gttccttcat tgagcacctc      240

ccaggccgac tgtgggaggg gagcaccagc cgggaacgtg ggagcacagg tacgcagctg      300

tgcaaggcct tggtgctgga gcagctgacc cctgccctgc acagcaccaa cttctcctgt      360

gtgctcgtgg accctgaaca ggttgtccag cgtcacgtcg tcctggccca gctctgggct      420

gggctgaggg caaccttgcc ccccacccaa gaagccctgc cctccagcca cagcagtcca      480

cagcagcagg gt                                                          492


<210>  3745
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  3745
tgtacttcac gtccccacat tactgtggtt gaaggggaac ctttctatct gaaacattgc       60

tcgtgttcac ttgcacatga gattgaaaca accaccaaaa gctggtacaa aagcagtgga      120

tcacaggaac atgtggagct gaacccaagg agttcctcga gaattgcttt gcatgattgt      180

gttttggagt tttggccagt tgagttgaat gacacaggat cttacttttt ccaaatgaaa      240

aattatactc agaaatggaa attaaatgtc atcagaagaa ataaacacag ctgtttcact      300

gaaagacaag taactagtaa aattgtggaa gttaaaaaat tttttcagat aacctgtgaa      360

aacagttact atcaaacact ggtcaacagc acatcattgt ataagaactg taaaaagcta      420

ctactggaga acaataaaaa cccaacgata aagaagaacg ccgagtttga agatcagggg      480

tattactcct gcgtgcattt ccttcatcat aatggaaaac tatttaatat caccaaaacc      540

ttcaatataa caatagtgga agatcgcagt aatatagttc cggttcttct tggaccaaag      600

cttaaccatg ttgcagtgga attaggaaaa aacgtaaggc tcaactgctc tgctttgctg      660

aatgaagagg atgtaattta ttggatgttc ggggaagaaa atggatcgga tcctaatata      720

catgaagaga aagaaatgag aattatgact ccagaaggca aatggcatgc ttcaaaagta      780

ttgagaattg aaaatattgg tgaaagcaat ctaaatgttt tatataattg cactgtggcc      840

agcacgggag gcacagacac caaaagcttc atcttggtga gaaaagcaga catggctgat      900

atcccaggcc acgtcttcac aaga                                             924


<210>  3746
<211>  1011
<212>  DNA
<213>  Homo Sapiens

<400>  3746
tttaatattt caggttgttc cacaaaaaaa ctcctttgga catattctac aaggagtgaa       60

gaggaatttg tcttattttg tgatttacca gagccacaga aatcacattt ctgccacaga      120

aatcgactct caccaaaaca agtccctgag cacctgccct tcatgggtag taacgaccta      180

tctgatgtcc aatggtacca acaaccttcg aatggagatc cattagagga cattaggaaa      240

agctatcctc acatcattca ggacaaatgt acccttcact ttttgacccc aggggtgaat      300

aattctgggt catatatttg tagacccaag atgattaaga gcccctatga tgtagcctgt      360

tgtgtcaaga tgattttaga agttaagccc cagacaaatg catcctgtga gtattccgca      420

tcacataagc aagacctact tcttgggagc actggctcta tttcttgccc cagtctcagc      480

tgccaaagtg atgcacaaag tccagcggta acctggtaca agaatggaaa actcctctct      540

gtggaaagga gcaaccgaat cgtagtggat gaagtttatg actatcacca gggcacatat      600

gtatgtgatt acactcagtc ggatactgtg agttcgtgga cagtcagagc tgttgttcaa      660

gtgagaacca ttgtgggaga cactaaactc aaaccagata ttctggatcc tgtcgaggac      720

acactggaag tagaacttgg aaagccttta actattagct gcaaagcacg atttggcttt      780

gaaagggtct ttaaccctgt cataaaatgg tacatcaaag attctgacct agagtgggaa      840

gtctcagtac ctgaggcgaa aagtattaaa tccactttaa aggatgaaat cattgagcgt      900

aatatcatct tggaaaaagt cactcagcgt gatcttcgca ggaagtttgt ttgctttgtc      960

cagaactcca ttggaaacac aacccagtcc gtccaactga aagaaaagag a              1011


<210>  3747
<211>  459
<212>  DNA
<213>  Homo Sapiens

<400>  3747
ctcaggagat gtctgatttc cacagacatg caccatatag aagagagttt ccaagaaatc       60

aaaagagcca tccaagctaa ggacaccttc ccaaatgtca ctatcctgtc cacattggag      120

actctgcaga tcattaagcc cttagatgtg tgctgcgtga ccaagaacct cctggcgttc      180

tacgtggaca gggtgttcaa ggatcatcag gagccaaacc ccaaaatctt gagaaaaatc      240

agcagcattg ccaactcttt cctctacatg cagaaaactc tgcggcaatg tcaggaacag      300

aggcagtgtc actgcaggca ggaagccacc aatgccacca gagtcatcca tgacaactat      360

gatcagctgg aggtccacgc tgctgccatt aaatccctgg gagagctcga cgtctttcta      420

gcctggatta ataagaatca tgaagtaatg ttctcagct                             459


<210>  3748
<211>  477
<212>  DNA
<213>  Homo Sapiens

<400>  3748
tcagcacctt ttagcttcct gagcaatgtg aaatacaact ttatgaggat catcaaatac       60

gaattcatcc tgaatgacgc cctcaatcaa agtataattc gagccaatga tcagtacctc      120

acggctgctg cattacataa tctggatgaa gcagtgaaat ttgacatggg tgcttataag      180

tcatcaaagg atgatgctaa aattaccgtg attctaagaa tctcaaaaac tcaattgtat      240

gtgactgccc aagatgaaga ccaaccagtg ctgctgaagg agatgcctga gatacccaaa      300

accatcacag gtagtgagac caacctcctc ttcttctggg aaactcacgg cactaagaac      360

tatttcacat cagttgccca tccaaacttg tttattgcca caaagcaaga ctactgggtg      420

tgcttggcag gggggccacc ctctatcact gactttcaga tactggaaaa ccaggcg         477


<210>  3749
<211>  459
<212>  DNA
<213>  Homo Sapiens

<400>  3749
gcacctgtac gatcactgaa ctgcacgctc cgggactcac agcaaaaaag cttggtgatg       60

tctggtccat atgaactgaa agctctccac ctccagggac aggatatgga gcaacaagtg      120

gtgttctcca tgtcctttgt acaaggagaa gaaagtaatg acaaaatacc tgtggccttg      180

ggcctcaagg aaaagaatct gtacctgtcc tgcgtgttga aagatgataa gcccactcta      240

cagctggaga gtgtagatcc caaaaattac ccaaagaaga agatggaaaa gcgatttgtc      300

ttcaacaaga tagaaatcaa taacaagctg gaatttgagt ctgcccagtt ccccaactgg      360

tacatcagca cctctcaagc agaaaacatg cccgtcttcc tgggagggac caaaggcggc      420

caggatataa ctgacttcac catgcaattt gtgtcttcc                             459


<210>  3750
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  3750
atgtgttccc tccccatggc aagatactac ataattaaat atgcagacca gaaggctcta       60

tacacaagag atggccagct gctggtggga gatcctgttg cagacaactg ctgtgcagag      120

aagatctgca cacttcctaa cagaggcttg gaccgcacca aggtccccat tttcctgggg      180

atccagggag ggagccgctg cctggcatgt gtggagacag aagaggggcc ttccctacag      240

ctggaggatg tgaacattga ggaactgtac aaaggtggtg aagaggccac acgcttcacc      300

ttcttccaga gcagctcagg ctccgccttc aggcttgagg ctgctgcctg gcctggctgg      360

ttcctgtgtg gcccggcaga gccccagcag ccagtacagc tcaccaagga gagtgagccc      420

tcagcccgta ccaagtttta ctttgaacag agctgg                                456


<210>  3751
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  3751
gtcctgagtg gggcgctgtg cttccgaatg aaggactcgg cattgaaggt gctttatctg       60

cataataacc agcttctagc tggagggctg catgcaggga aggtcattaa aggtgaagag      120

atcagcgtgg tccccaatcg gtggctggat gccagcctgt cccccgtcat cctgggtgtc      180

cagggtggaa gccagtgcct gtcatgtggg gtggggcagg agccgactct aacactagag      240

ccagtgaaca tcatggagct ctatcttggt gccaaggaat ccaagagctt caccttctac      300

cggcgggaca tggggctcac ctccagcttc gagtcggctg cctacccggg ctggttcctg      360

tgcacggtgc ctgaagccga tcagcctgtc agactcaccc agcttcccga gaatggtggc      420

tggaatgccc ccatcacaga cttctacttc cagcagtgtg ac                         462


<210>  3752
<211>  459
<212>  DNA
<213>  Homo Sapiens

<400>  3752
aaaattgaca cacctcagca ggggagcatt caggatatca atcatcgggt gtgggttctt       60

caggaccaga cgctcatagc agtcccgagg aaggaccgta tgtctccagt cactattgcc      120

ttaatctcat gccgacatgt ggagaccctt gagaaagaca gagggaaccc catctacctg      180

ggcctgaatg gactcaatct ctgcctgatg tgtgctaaag tcggggacca gcccacactg      240

cagctgaagg aaaaggatat aatggatttg tacaaccaac ccgagcctgt gaagtccttt      300

ctcttctacc acagccagag tggcaggaac tccaccttcg agtctgtggc tttccctggc      360

tggttcatcg ctgtcagctc tgaaggaggc tgtcctctca tccttaccca agaactgggg      420

aaagccaaca ctactgactt tgggttaact atgctgttt                             459


<210>  3753
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  3753
gttcacacaa gtccaaaggt gaagaactta aacccgaaga aattcagcat tcatgaccag       60

gatcacaaag tactggtcct ggactctggg aatctcatag cagttccaga taaaaactac      120

atacgcccag agatcttctt tgcattagcc tcatccttga gctcagcctc tgcggagaaa      180

ggaagtccga ttctcctggg ggtctctaaa ggggagtttt gtctctactg tgacaaggat      240

aaaggacaaa gtcatccatc ccttcagctg aagaaggaga aactgatgaa gctggctgcc      300

caaaaggaat cagcacgccg gcccttcatc ttttataggg ctcaggtggg ctcctggaac      360

atgctggagt cggcggctca ccccggatgg ttcatctgca cctcctgcaa ttgtaatgag      420

cctgttgggg tgacagataa atttgagaac aggaaacaca ttgaattttc atttcaacca      480

gtttgcaaag ctgaaatgag ccccagtgag gtcagcgat                             519


<210>  3754
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  3754
tcaatgtgta aacctattac tgggactatt aatgatttga atcagcaagt gtggaccctt       60

cagggtcaga accttgtggc agttccacga agtgacagtg tgaccccagt cactgttgct      120

gttatcacat gcaagtatcc agaggctctt gagcaaggca gaggggatcc catttatttg      180

ggaatccaga atccagaaat gtgtttgtat tgtgagaagg ttggagaaca gcccacattg      240

cagctaaaag agcagaagat catggatctg tatggccaac ccgagcccgt gaaacccttc      300

cttttctacc gtgccaagac tggtaggacc tccacccttg agtctgtggc cttcccggac      360

tggttcattg cctcctccaa gagagaccag cccatcattc tgacttcaga acttgggaag      420

tcatacaaca ctgcctttga attaaatata aatgac                                456


<210>  3755
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3755
ctggaggctg ataaatgcaa ggaacgtgaa gaaaaaataa ttttagtgtc atctgcaaat       60

gaaattgatg ttcgtccctg tcctcttaac ccaaatgaac acaaaggcac tataacttgg      120

tataaagatg acagcaagac acctgtatct acagaacaag cctccaggat tcatcaacac      180

aaagagaaac tttggtttgt tcctgctaag gtggaggatt caggacatta ctattgcgtg      240

gtaagaaatt catcttactg cctcagaatt aaaataagtg caaaatttgt ggagaatgag      300

cctaacttat gttataatgc acaagccata tttaagcaga aactacccgt tgcaggagac      360

ggaggacttg tgtgccctta tatggagttt tttaaaaatg aaaataatga gttacctaaa      420

ttacagtggt ataaggattg caaacctcta cttcttgaca atatacactt tagtggagtc      480

aaagataggc tcatcgtgat gaatgtggct gaaaagcata gagggaacta tacttgtcat      540

gcatcctaca catacttggg caagcaatat cctattaccc gggtaataga atttattact      600

ctagaggaaa acaaacccac aaggcctgtg attgtgagcc cagctaatga gacaatggaa      660

gtagacttgg gatcccagat acaattgatc tgtaatgtca ccggccagtt gagtgacatt      720

gcttactgga agtggaatgg gtcagtaatt gatgaagatg acccagtgct aggggaagac      780

tattacagtg tggaaaatcc tgcaaacaaa agaaggagta ccctcatcac agtgcttaat      840

atatcggaaa ttgaaagtag attttataaa catccattta cctgttttgc caagaataca      900

catggtatag atgcagcata tatccagtta atatatccag tcactaattt ccagaag         957


<210>  3756
<211>  990
<212>  DNA
<213>  Homo Sapiens

<400>  3756
ttcacccttc agcctgcggc acacacaggg gctgccagaa gctgccggtt tcgtgggagg       60

cattacaagc gggagttcag gctggaaggg gagcctgtag ccctgaggtg cccccaggtg      120

ccctactggt tgtgggcctc tgtcagcccc cgcatcaacc tgacatggca taaaaatgac      180

tctgctagga cggtcccagg agaagaagag acacggatgt gggcccagga cggtgctctg      240

tggcttctgc cagccttgca ggaggactct ggcacctacg tctgcactac tagaaatgct      300

tcttactgtg acaaaatgtc cattgagctc agagtttttg agaatacaga tgctttcctg      360

ccgttcatct catacccgca aattttaacc ttgtcaacct ctggggtatt agtatgccct      420

gacctgagtg aattcacccg tgacaaaact gacgtgaaga ttcaatggta caaggattct      480

cttcttttgg ataaagacaa tgagaaattt ctaagtgtga gggggaccac tcacttactc      540

gtacacgatg tggccctgga agatgctggc tattaccgct gtgtcctgac atttgcccat      600

gaaggccagc aatacaacat cactaggagt attgagctac gcatcaagaa aaaaaaagaa      660

gagaccattc ctgtgatcat ttcccccctc aagaccatat cagcttctct ggggtcaaga      720

ctgacaatcc cgtgtaaggt gtttctggga accggcacac ccttaaccac catgctgtgg      780

tggacggcca atgacaccca catagagagc gcctacccgg gaggccgcgt gaccgagggg      840

ccacgccagg aatattcaga aaataatgag aactacattg aagtgccatt gatttttgat      900

cctgtcacaa gagaggattt gcacatggat tttaaatgtg ttgtccataa taccctgagt      960

tttcagacac tacgcaccac agtcaaggaa                                       990


<210>  3757
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  3757
tcagaacgct gcgatgactg gggactagac accatgaggc aaatccaagt gtttgaagat       60

gagccagctc gcatcaagtg cccactcttt gaacacttct tgaaattcaa ctacagcaca      120

gcccattcag ctggccttac tctgatctgg tattggacta ggcaggaccg ggaccttgag      180

gagccaatta acttccgcct ccccgagaac cgcattagta aggagaaaga tgtgctgtgg      240

ttccggccca ctctcctcaa tgacactggc aactatacct gcatgttaag gaacactaca      300

tattgcagca aagttgcatt tcccttggaa gttgttcaaa aagacagctg tttcaattcc      360

cccatgaaac tcccagtgca taaactgtat atagaatatg gcattcagag gatcacttgt      420

ccaaatgtag atggatattt tccttccagt gtcaaaccga ctatcacttg gtatatgggc      480

tgttataaaa tacagaattt taataatgta atacccgaag gtatgaactt gagtttcctc      540

attgccttaa tttcaaataa tggaaattac acatgtgttg ttacatatcc agaaaatgga      600

cgtacgtttc atctcaccag gactctgact gtaaaggtag taggctctcc aaaaaatgca      660

gtgccccctg tgatccattc acctaatgat catgtggtct atgagaaaga accaggagag      720

gagctactca ttccctgtac ggtctatttt agttttctga tggattctcg caatgaggtt      780

tggtggacca ttgatggaaa aaaacctgat gacatcacta ttgatgtcac cattaacgaa      840

agtataagtc atagtagaac agaagatgaa acaagaactc agattttgag catcaagaaa      900

gttacctctg aggatctcaa gcgcagctat gtctgtcatg ctagaagtgc caaaggcgaa      960

gttgccaaag cagccaaggt gaagcagaaa ggtaatagat gcggtcag                  1008


<210>  3758
<211>  1017
<212>  DNA
<213>  Homo Sapiens

<400>  3758
ttgaaggttg tgaccaaaag aggctccgcc gatggatgca ctgactggtc tatcgatatc       60

aagaaatatc aagttttggt gggagagcct gttcgaatca aatgtgcact cttttatggt      120

tatatcagaa caaattactc ccttgcccaa agtgctggac tcagtttgat gtggtacaaa      180

agttctggtc ctggagactt tgaagagcca atagcctttg acggaagtag aatgagcaaa      240

gaagaagact ccatttggtt ccggccaaca ttgctacagg acagtggtct ctacgcctgt      300

gtcatcagaa actccactta ctgtatgaaa gtatccatct cactgacagt gggtgaaaat      360

gacactggac tctgctataa ttccaagatg aagtattttg aaaaagctga acttagcaaa      420

agcaaggaaa tttcatgccg tgacatagag gattttctac tgccaaccag agaacctgaa      480

atcctttggt acaaggaatg caggacaaaa acatggaggc caagtattgt attcaaaaga      540

gatactctgc ttataagaga agtcagagaa gatgacattg gaaattatac ctgtgaatta      600

aaatatggag gctttgttgt gagaagaact actgaattaa ctgttacagc ccctctgact      660

gataagccac ccaagctttt gtatcctatg gaaagtaaac tgacaattca ggagacccag      720

ctgggtgact ctgctaatct aacctgcaga gctttctttg ggtacagcgg agatgtcagt      780

cctttaattt actggatgaa aggagaaaaa tttattgaag atctggatga aaatcgagtt      840

tgggaaagtg acattagaat tcttaaggag catcttgggg aacaggaagt ttccatctca      900

ttaattgtgg actctgtgga agaaggtgac ttgggaaatt actcctgtta tgttgaaaat      960

ggaaatggac gtcgacacgc cagcgttctc cttcataaac gagagctaat gtacaca        1017


<210>  3759
<211>  1014
<212>  DNA
<213>  Homo Sapiens

<400>  3759
acaaatctga agatggtgtc aaagagaaat tctgtggatg gctgcattga ctggtcagtg       60

gatctcaaga catacatggc tttggcaggt gaaccagtcc gagtgaaatg tgcccttttc      120

tacagttata ttcgtaccaa ctatagcacg gcccagagca ctgggctcag gcttatgtgg      180

tacaaaaaca aaggtgattt ggaagagccc atcatctttt cagaggtcag gatgagcaaa      240

gaggaagatt caatatggtt tcactcagct gaggcacaag acagtggatt ctacacttgt      300

gttttaagaa actcaacata ttgcatgaag gtgtcaatgt ccttgactgt tgcagagaat      360

gaatcaggcc tgtgctacaa cagcaggatc cgctatttag aaaaatctga agtcactaaa      420

agaaaggaga tctcctgtcc agacatggat gactttaaaa agtccgatca ggagcctgat      480

gttgtgtggt ataaggaatg caagccaaaa atgtggagaa gcataataat acagaaagga      540

aatgctcttc tgatccaaga agttcaagaa gaagatggag gaaattacac atgtgaactt      600

aaatatgaag gaaaacttgt aagacgaaca actgaattga aagttacagc tttactcaca      660

gacaagcctc ccaagccatt gttccccatg gagaatcagc caagtgttat agatgtccag      720

ctgggtaagc ctctgaacat cccctgcaaa gcattcttcg gattcagtgg agagtctggg      780

ccaatgatct actggatgaa aggagaaaag tttattgaag aactggcagg tcacattaga      840

gaaggtgaaa taaggcttct caaagagcat cttggagaaa aagaagttga attggcactc      900

atctttgact cagttgtgga agctgacctg gcgaattata cctgccatgt tgaaaaccga      960

aatggacgga aacatgccag tgttttgctg cgtaaaaagg atttaatcta taaa           1014


<210>  3760
<211>  930
<212>  DNA
<213>  Homo Sapiens

<400>  3760
aagtttagta aacaatcatg gggcctggaa aatgaggctt taattgtaag atgtcctaga       60

caaggaaaac ctagttacac cgtggattgg tattactcac aaacaaacaa aagtattccc      120

actcaggaaa gaaatcgtgt gtttgcctca ggccaacttc tgaagtttct accagctgca      180

gttgctgatt ctggtattta tacctgtatt gtcagaagtc ccacattcaa taggactgga      240

tatgcgaatg tcaccatata taaaaaacaa tcagattgca atgttccaga ttatttgatg      300

tattcaacag tatctggatc agaaaaaaat tccaaaattt attgtcctac cattgacctc      360

tacaactgga cagcacctct tgagtggttt aagaattgtc aggctcttca aggatcaagg      420

tacagggcgc acaagtcatt tttggtcatt gataatgtga tgactgagga cgcaggtgat      480

tacacctgta aatttataca caatgaaaat ggagccaatt atagtgtgac ggcgaccagg      540

tccttcacgg tcaaggatga gcaaggcttt tctctgtttc cagtaatcgg agcccctgca      600

caaaatgaaa taaaggaagt ggaaattgga aaaaacgcaa acctaacttg ctctgcttgt      660

tttggaaaag gcactcagtt cttggctgcc gtcctgtggc agcttaatgg aacaaaaatt      720

acagactttg gtgaaccaag aattcaacaa gaggaagggc aaaatcaaag tttcagcaat      780

gggctggctt gtctagacat ggttttaaga atagctgacg tgaaggaaga ggatttattg      840

ctgcagtacg actgtctggc cctgaatttg catggcttga gaaggcacac cgtaagacta      900

agtaggaaaa atccaagtaa ggagtgtttc                                       930


<210>  3761
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  3761
atgacagggc tcgtgtccct gtcatatttt ccactctcca cgaggtcctg cgcgcttcaa       60

tcctgcagcc cggtttgggg atgtggtcct tgctgctctg cgggttgtcc atcgcccttc      120

cactgtctgt cacagcagga ctgtaacgag attaaagggg agcggttcac tgttttggaa      180

accaggcttt tggtgagcaa tgtctcggca gaggacagag ggaactacgc gtgtcaagcc      240

atactgacac actcagggaa gcagtacgag gttttaaatg gcatcactgt gagcattaaa      300

agagctggat atggaggaag tgtccctaaa atcatttatc caaaaaatca ttcaattgaa      360

gtacagcttg gtaccactct gattgtggac tgcaatgtaa cagacaccaa ggataataca      420

aatctacgat gctggagagt caataacact ttggtggatg attactatga tgaatccaaa      480

cgaatcagag aaggggtgga aacccatgtc tcttttcggg aacataattt gtacacagta      540

aacatcacct tcttggaagt gaaaatggaa gattatggcc ttcctttcat gtgccacgct      600

ggagtgtcca cagcatacat tatattacag ctcccagctc cggattttcg a               651


<210>  3762
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  3762
cgaccctctg ggagaaaatc cagcaagatg caagccttca gaatctggga tgttaaccag       60

aagaccttct atctgaggaa caaccaacta gttgccggat acttgcaagg accaaatgtc      120

aatttagaag aaaagataga tgtggtaccc attgagcctc atgctctgtt cttgggaatc      180

catggaggga agatgtgcct gtcctgtgtc aagtctggtg atgagaccag actccagctg      240

gaggcagtta acatcactga cctgagcgag aacagaaagc aggacaagcg cttcgccttc      300

atccgctcag acagtggccc caccaccagt tttgagtctg ccgcctgccc cggttggttc      360

ctctgcacag cgatggaagc tgaccagccc gtcagcctca ccaatatgcc tgacgaaggc      420

gtcatggtca ccaaattcta cttccaggag gacgag                                456


<210>  3763
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3763
gcacctactt caagttctac aaagaaaaca cagctacaac tggagcattt actgctggat       60

ttacagatga ttttgaatgg aattaataat tacaagaatc ccaaactcac caggatgctc      120

acatttaagt tttacatgcc caagaaggcc acagaactga aacatcttca gtgtctagaa      180

gaagaactca aacctctgga ggaagtgcta aatttagctc aaagcaaaaa ctttcactta      240

agacccaggg acttaatcag caatatcaac gtaatagttc tggaactaaa gggatctgaa      300

acaacattca tgtgtgaata tgctgatgag acagcaacca ttgtagaatt tctgaacaga      360

tggattacct tttgtcaaag catcatctca acactgact                             399


<210>  3764
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  3764
ctgaagacac tcaatttggg aagctgtgtg atcgccacaa accttcagga aatacgaaat       60

ggattttctg agatacgggg cagtgtgcaa gccaaagatg gaaacattga catcagaatc      120

ttaaggagga ctgagtcttt gcaagacaca aagcctgcga atcgatgctg cctcctgcgc      180

catttgctaa gactctatct ggacagggta tttaaaaact accagacccc tgaccattat      240

actctccgga agatcagcag cctcgccaat tcctttctta ccatcaagaa ggacctccgg      300

ctctgtcatg cccacatgac atgccattgt ggggaggaag caatgaagaa atacagccag      360

attctgagtc actttgaaaa gctggaacct caggcagcag ttgtgaaggc tttgggggaa      420

ctagacattc ttctgcaatg gatggaggag acagaa                                456


<210>  3765
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  3765
gttccctgtg tctctggtgg tttgcctaaa cctgcaaaca tcaccttctt atccatcaac       60

atgaagaatg tcctacaatg gactccacca gagggtcttc aaggagttaa agttacttac      120

actgtgcagt atttcatata tgggcaaaag aaatggctga ataaatcaga atgcagaaat      180

atcaatagaa cctactgtga tctttctgct gaaacttctg actacgaaca ccagtattat      240

gccaaagtta aggccatttg gggaacaaag tgttccaaat gggctgaaag tggacggttc      300

tatccttttt tagaaacaca aattggccca ccagaggtgg cactgactac agatgagaag      360

tccatttctg ttgtcctgac agctccagag aagtggaaga gaaatccaga agaccttcct      420

gtttccatgc aacaaatata ctccaatctg aagtataacg tgtctgtgtt gaatactaaa      480

tcaaacagaa cgtggtccca gtgtgtgacc aaccacacgc tggtgctcac ctggctggag      540

ccgaacactc tttactgcgt acacgtggag tccttcgtcc cagggccccc tcgccgtgct      600

cagccttctg agaagcagtg tgccaggact ttgaaagatc aatcatcaga gttcaaggct      660

aaa                                                                    663


<210>  3766
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  3766
gatgaagtgg ccattctgcc tgcccctcag aacctctctg tactctcaac caacatgaag       60

catctcttga tgtggagccc agtgatcgcg cctggagaaa cagtgtacta ttctgtcgaa      120

taccaggggg agtacgagag cctgtacacg agccacatct ggatccccag cagctggtgc      180

tcactcactg aaggtcctga gtgtgatgtc actgatgaca tcacggccac tgtgccatac      240

aaccttcgtg tcagggccac attgggctca cagacctcag cctggagcat cctgaagcat      300

ccctttaata gaaactcaac catccttacc cgacctggga tggagatcac caaagatggc      360

ttccacctgg ttattgagct ggaggacctg gggccccagt ttgagttcct tgtggcctac      420

tggaggaggg agcctggtgc cgaggaacat gtcaaaatgg tgaggagtgg gggtattcca      480

gtgcacctag aaaccatgga gccaggggct gcatactgtg tgaaggccca gacattcgtg      540

aaggccattg ggaggtacag cgccttcagc cagacagaat gtgtggaggt gcaaggagag      600

gccattcccc tg                                                          612


<210>  3767
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3767
caaggtcaag atcgccacat gattagaatg cgtcaactta tagatattgt tgatcagctg       60

aaaaattatg tgaatgactt ggtccctgaa tttctgccag ctccagaaga tgtagagaca      120

aactgtgagt ggtcagcttt ttcctgcttt cagaaggccc aactaaagtc agcaaataca      180

ggaaacaatg aaaggataat caatgtatca attaaaaagc tgaagaggaa accaccttcc      240

acaaatgcag ggagaagaca gaaacacaga ctaacatgcc cttcatgtga ttcttatgag      300

aaaaaaccac ccaaagaatt cctagaaaga ttcaaatcac ttctccaaaa gatgattcat      360

cagcatctgt cctctagaac acacggaagt gaagattcc                             399


<210>  3768
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  3768
tgccccgacc tcgtctgcta caccgattac ctccagacgg tcatctgcat cctggaaatg       60

tggaacctcc accccagcac gctcaccctt acctggcaag accagtatga agagctgaag      120

gacgaggcca cctcctgcag cctccacagg tcggcccaca atgccacgca tgccacctac      180

acctgccaca tggatgtatt ccacttcatg gccgacgaca ttttcagtgt caacatcaca      240

gaccagtctg gcaactactc ccaggagtgt ggcagctttc tcctggctga gagcatcaag      300

ccggctcccc ctttcaacgt gactgtgacc ttctcaggac agtataatat ctcctggcgc      360

tcagattacg aagaccctgc cttctacatg ctgaagggca agcttcagta tgagctgcag      420

tacaggaacc ggggagaccc ctgggctgtg agtccgagga gaaagctgat ctcagtggac      480

tcaagaagtg tctccctcct ccccctggag ttccgcaaag actcgagcta tgagctgcag      540

gtgcgggcag ggcccatgcc tggctcctcc taccagggga cctggagtga atggagtgac      600

ccggtcatct ttcagaccca gtcagaggag ttaaaggaa                             639


<210>  3769
<211>  438
<212>  DNA
<213>  Homo Sapiens

<400>  3769
gcgcccatca gctcccactg caggcttgac aagtccaact tccagcagcc ctatatcacc       60

aaccgcacct tcatgctggc taaggaggct agcttggctg ataacaacac agacgttcgt      120

ctcattgggg agaaactgtt ccacggagtc agtatgagtg agcgctgcta tctgatgaag      180

caggtgctga acttcaccct tgaagaagtg ctgttccctc aatctgatag gttccagcct      240

tatatgcagg aggtggtgcc cttcctggcc aggctcagca acaggctaag cacatgtcat      300

attgaaggtg atgacctgca tatccagagg aatgtgcaaa agctgaagga cacagtgaaa      360

aagcttggag agagtggaga gatcaaagca attggagaac tggatttgct gtttatgtct      420

ctgagaaatg cctgcatt                                                    438


<210>  3770
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  3770
cacgcccctg aggacccctc ggatctgctc cagcacgtga aattccagtc cagcaacttt       60

gaaaacatcc tgacgtggga cagcgggccg gagggcaccc cagacacggt ctacagcatc      120

gagtataaga cgtacggaga gagggactgg gtggcaaaga agggctgtca gcggatcacc      180

cggaagtcct gcaacctgac ggtggagacg ggcaacctca cggagctcta ctatgccagg      240

gtcaccgctg tcagtgcggg aggccggtca gccaccaaga tgactgacag gttcagctct      300

ctgcagcaca ctaccctcaa gccacctgat gtgacctgta tctccaaagt gagatcgatt      360

cagatgattg ttcatcctac ccccacgccc atccgtgcag gcgatggcca ccggctaacc      420

ctggaagaca tcttccatga cctgttctac cacttagagc tccaggtcaa ccgcacctac      480

caaatgcacc ttggagggaa gcagagagaa tatgagttct tcggcctgac ccctgacaca      540

gagttccttg gcaccatcat gatttgcgtt cccacctggg ccaaggagag tgccccctac      600

atgtgccgag tgaagacact gccagaccgg acatggacc                             639


<210>  3771
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  3771
actcagtcaa cgcatgagtc tctgaagcct cagagggtac aatttcagtc ccgaaatttt       60

cacaacattt tgcaatggca gcctgggagg gcacttactg gcaacagcag tgtctatttt      120

gtgcagtaca aaatatatgg acagagacaa tggaaaaata aagaagactg ttggggtact      180

caagaactct cttgtgacct taccagtgaa acctcagaca tacaggaacc ttattacggg      240

agggtgaggg cggcctcggc tgggagctac tcagaatgga gcatgacgcc gcggttcact      300

ccctggtggg aaacaaaaat agatcctcca gtcatgaata taacccaagt caatggctct      360

ttgttggtaa ttctccatgc tccaaattta ccatatagat accaaaagga aaaaaatgta      420

tctatagaag attactatga actactatac cgagttttta taattaacaa ttcactagaa      480

aaggagcaaa aggtttatga aggggctcac agagcggttg aaattgaagc tctaacacca      540

cactccagct actgtgtagt ggctgaaata tatcagccca tgttagacag aagaagtcag      600

agaagtgaag agagatgtgt ggaaattcca                                       630


<210>  3772
<211>  510
<212>  DNA
<213>  Homo Sapiens

<400>  3772
agagctgtgc ctgggggcag cagccctgcc tggactcagt gccagcagct ttcacagaag       60

ctctgcacac tggcctggag tgcacatcca ctagtgggac acatggatct aagagaagag      120

ggagatgaag agactacaaa tgatgttccc catatccagt gtggagatgg ctgtgacccc      180

caaggactca gggacaacag tcagttctgc ttgcaaagga tccaccaggg tctgattttt      240

tatgagaagc tgctaggatc ggatattttc acaggggagc cttctctgct ccctgatagc      300

cctgtgggcc agcttcatgc ctccctactg ggcctcagcc aactcctgca gcctgagggt      360

caccactggg agactcagca gattccaagc ctcagtccca gccagccatg gcagcgtctc      420

cttctccgct tcaaaatcct tcgcagcctc caggcctttg tggctgtagc cgcccgggtc      480

tttgcccatg gagcagcaac cctgagtccc                                       510


<210>  3773
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  3773
gggattacca acattaactg cagtgggcat atatgggtag aacctgcaac aatatttaag       60

atgggtatga atatcagtat atactgtcaa gcggctatca agaattgtca acctcgtaaa      120

ttgcattttt ataagaacgg gataaaagaa aggttccaaa tcacccgtat caacaagacc      180

accgccaggc tttggtacaa gaatttcttg gaaccacacg cgtccatgta ctgtaccgct      240

gagtgcccca agcactttca ggaaactcta atatgtggca aagacataag ttccggctat      300

ccaccggaca ttccagatga ggtaacttgt gtgatatatg agtacagtgg gaacatgaca      360

tgcacctgga atgccgggaa gctaacgtac atagatacca agtacgtggt gcacgtgaag      420

tccctggaga ctgaagaaga acagcagtat cttacttcct cttatataaa catatccact      480

gactcacttc aaggaggcaa gaaatacctt gtgtgggtgc aagctgcgaa cgcgctgggc      540

atggaggagt ccaaacagct tcaaatacat ttggacgata tagtgattcc aagtgccgcg      600

gttatctcac gtgcagaaac tattaatgct acggttccta agacgatcat atattgggac      660

agccaaacta ctatcgaaaa agtctcctgc gagatgagat ataaagcaac aactaatcag      720

acatggaatg tcaaggagtt tgatacgaac ttcacttacg tacagcagag cgaattttat      780

ttagagccta atataaagta cgtcttccaa gtaagatgtc aagaaactgg taagaggtac      840

tggcaaccct ggtcaagtct attttttcac aaaacaccag agaccgtacc acaagtgact      900

agcaaggcct ttcaacatga cacatggaac agtggtctaa ctgttgcttc aatcagcacg      960

ggtcatttga cgagcgataa tagaggcgac atcggg                                996


<210>  3774
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  3774
caagaattcc actttgggcc ctgccaagtg aagggggttg ttccccagaa actgtgggaa       60

gccttctggg ctgtgaaaga cactatgcaa gctcaggata acatcacgag tgcccggctg      120

ctgcagcagg aggttctgca gaacgtctcg gatgctgaga gctgttacct tgtccacacc      180

ctgctggagt tctacttgaa aactgttttc aaaaactacc acaatagaac agttgaagtc      240

aggactctga agtcattctc tactctggcc aacaactttg ttctcatcgt gtcacaactg      300

caacccagtc aagaaaatga gatgttttcc atcagagaca gtgcacacag gcggtttctg      360

ctattccgga gagcattcaa acagttggac gtagaagcag ctctgaccaa agcccttggg      420

gaagtggaca ttcttctgac ctggatgcag aaattctaca agctc                      465


<210>  3775
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  3775
tacagccact ggcccagctg ctgccccagc aaagggcagg acacctctga ggagctgctg       60

aggtggagca ctgtgcctgt gcctccccta gagcctgcta ggcccaaccg ccacccagag      120

tcctgtaggg ccagtgaaga tggacccctc aacagcaggg ccatctcccc ctggagatat      180

gagttggaca gagacttgaa ccggctcccc caggacctgt accacgcccg ttgcctgtgc      240

ccgcactgcg tcagcctaca gacaggctcc cacatggacc cccggggcaa ctcggagctg      300

ctctaccaca accagactgt cttctacagg cggccatgcc atggcgagaa gggcacccac      360

aagggctact gcctggagcg caggctgtac cgtgtttcct tagcttgtgt gtgtgtgcgg      420

ccccgtgtga tgggc                                                       435


<210>  3776
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  3776
aagcacaagc aatcttcctt caccaaaagt tgttacccaa ggggaacatt gtcccaagct       60

gttgacgctc tctatatcaa agcagcatgg ctcaaagcaa cgattccaga agaccgcata      120

aaaaatatac gattattaaa aaagaaaaca aaaaagcagt ttatgaaaaa ctgtcaattt      180

caagaacagc ttctgtcctt cttcatggaa gacgtttttg gtcaactgca attgcaaggc      240

tgcaagaaaa tacgctttgt ggaggacttt catagcctta ggcagaaatt gagccactgt      300

atttcctgtg cttcatcagc tagagagatg aaatccatta ccaggatgaa aagaatattt      360

tataggattg gaaacaaagg aatctacaaa gccatcagtg aactggatat tcttctttcc      420

tggattaaaa aattattgga aagcagtcag                                       450


<210>  3777
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  3777
ttcccaaggc ccccagggag gccccagctg agcctgcagg agctgcggag ggagttcaca       60

gtcagcctgc atctcgccag gaagctgctc gccgaggttc ggggccaggc ccaccgcttt      120

gcggaatctc acctgccagg agtgaacctg tacctcctgc ccctgggaga gcagctccct      180

gatgtttccc tgaccttcca ggcctggcgc cgcctctctg acccggagcg tctctgcttc      240

atctccacca cgcttcagcc cttccatgcc ctgctgggag ggctggggac ccagggccgc      300

tggaccaaca tggagaggat gcagctgtgg gccatgaggc tggacctccg cgatctgcag      360

cggcacctcc gcttccaggt gctggctgca ggattcaacc tcccggagga ggaggaggag      420

gaagaggagg aggaggagga ggagaggaag gggctgctcc caggggcact gggcagcgcc      480

ttacagggcc cggcccaggt gtcctggccc cagctcctct ccacctaccg cctgctgcac      540

tccttggagc tcgtcttatc tcgggccgtg cgggagttgc tgctgctgtc caaggctggg      600

cactcagtct ggcccttggg gttcccaaca ttgagccccc agccc                      645


<210>  3778
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  3778
cagggcagcg ccgggccact gcagtgctac ggagttggac ccttgggcga cttgaactgc       60

tcgtgggagc ctcttgggga cctgggagcc ccctccgagt tacacctcca gagccaaaag      120

taccgttcca acaaaaccca gactgtggca gtggcagccg gacggagctg ggtggccatt      180

cctcgggaac agctcaccat gtctgacaaa ctccttgtct ggggcactaa ggcaggccag      240

cctctctggc cccccgtctt cgtgaaccta gaaacccaaa tgaagccaaa cgccccccgg      300

ctgggccctg acgtggactt ttccgaggat gaccccctgg aggccactgt ccattgggcc      360

ccacctacat ggccatctca taaagttctg atctgccagt tccactaccg aagatgtcag      420

gaggcggcct ggaccctgct ggaaccggag ctgaagacca tacccctgac ccctgttgag      480

atccaagatt tggagctagc cactggctac aaagtgtatg gccgctgccg gatggagaaa      540

gaagaggatt tgtggggcga gtggagcccc attttgtcct tccagacacc gccttctgct      600

ccaaaagatg tgtgggtatc agggaacctc tgtgggacgc ctggaggaga ggaacctttg      660

cttctatgga aggccccagg gccctgtgtg caggtgagct acaaagtctg gttctgggtt      720

ggaggtcgtg agctgagtcc agaaggaatt acctgctgct gctccctaat tcccagtggg      780

gcggagtggg ccagggtgtc cgctgtcaac gccacaagct gggagcctct caccaacctc      840

tctttggtct gcttggattc agcctctgcc ccccgtagcg tggcagtcag cagcatcgct      900

gggagcacgg agctactggt gacctggcaa ccggggcctg gggaaccact ggagcatgta      960

gtggactggg ctcgagatgg ggaccccctg gagaaactca actgggtccg gcttccccct     1020

gggaacctca gtgctctgtt accagggaat ttcactgtcg gggtccccta tcgaatcact     1080

gtgaccgcag tctctgcttc aggcttggcc tctgcatcct ccgtctgggg gttcagggag     1140

gaattagcac ccctagtggg gccaacgctt tggcgactcc aagatgcccc tccagggacc     1200

cccgccatag cgtggggaga ggtcccaagg caccagcttc gaggccacct cacccactac     1260

accttgtgtg cacagagtgg aaccagcccc tccgtctgca tgaatgtgag tggcaacaca     1320

cagagtgtca ccctgcctga ccttccttgg ggtccctgtg agctgtgggt gacagcatct     1380

accatcgctg gacagggccc tcctggtccc atcctccggc ttcatctacc agataacacc     1440

ctgaggtgga aa                                                         1452


<210>  3779
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  3779
gttcctgtcg ccaggctccg cggggctctc ccggatgcaa ggggctgcca catagcccag       60

ttcaagtccc tgtctccaca ggagctgcag gcctttaaga gggccaaaga tgccttagaa      120

gagtcgcttc tgctgaagga ctgcaagtgc cgctcccgcc tcttccccag gacctgggac      180

ctgaggcagc tgcaggtgag ggagcgcccc gtggctttgg aggctgagct ggccctgacg      240

ctgaaggttc tggaggccac cgctgacact gacccagccc tgggggatgt cttggaccag      300

ccccttcaca ccctgcacca tatcctctcc cagctccggg cctgtatcca gcctcagccc      360

acggcagggc ccaggacccg gggccgcctc caccattggc tgcaccggct ccaggaggcc      420

ccaaaaaagg agtcccctgg ctgcctcgag gcctctgtca ccttcaacct cttccgcctc      480

ctcacgcgag acctgaattg tgttgccagc ggggacctgt gtgtc                      525


<210>  3780
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  3780
aggccccgtc tggcccctcc ccagaatgtg acgctgctct cccagaactt cagcgtgtac       60

ctgacatggc tcccagggct tggcaacccc caggatgtga cctattttgt ggcctatcag      120

agctctccca cccgtagacg gtggcgcgaa gtggaagagt gtgcgggaac caaggagctg      180

ctatgttcta tgatgtgcct gaagaaacag gacctgtaca acaagttcaa gggacgcgtg      240

cggacggttt ctcccagctc caagtccccc tgggtggagt ccgaatacct ggattacctt      300

tttgaagtgg agccggcccc acctgtcctg gtgctcaccc agacggagga gatcctgagt      360

gccaatgcca cgtaccagct gcccccctgc atgcccccac tggatctgaa gtatgaggtg      420

gcattctgga aggagggggc cggaaacaag accctatttc cagtcactcc ccatggccag      480

ccagtccaga tcactctcca gccagctgcc agcgaacacc actgcctcag tgccagaacc      540

atctacacgt tcagtgtccc gaaatacagc aagttctcta agcccacctg cttcttgctg      600

gaggtcccag aagccaactg ggct                                             624


<210>  3781
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  3781
ggccctgtcc ccacttccaa gcccaccaca actgggaagg gctgccacat tggcaggttc       60

aaatctctgt caccacagga gctagcgagc ttcaagaagg ccagggacgc cttggaagag      120

tcactcaagc tgaaaaactg gagttgcagc tctcctgtct tccccgggaa ttgggacctg      180

aggcttctcc aggtgaggga gcgccctgtg gccttggagg ctgagctggc cctgacgctg      240

aaggtcctgg aggccgctgc tggcccagcc ctggaggacg tcctagacca gccccttcac      300

accctgcacc acatcctctc ccagctccag gcctgtatcc agcctcagcc cacagcaggg      360

cccaggcccc ggggccgcct ccaccactgg ctgcaccggc tccaggaggc ccccaaaaag      420

gagtccgctg gctgcctgga ggcatctgtc accttcaacc tcttccgcct cctcacgcga      480

gacctcaaat atgtggccga tgggaacctg tgtctgagaa cgtcaaccca ccctgagtcc      540

acc                                                                    543


<210>  3782
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3782
gagctctgtg acgatgaccc gccagagatc ccacacgcca cattcaaagc catggcctac       60

aaggaaggaa ccatgttgaa ctgtgaatgc aagagaggtt tccgcagaat aaaaagcggg      120

tcactctata tgctctgtac aggaaactct agccactcgt cctgggacaa ccaatgtcaa      180

tgcacaagct ctgccactcg gaacacaacg aaacaagtga cacctcaacc tgaagaacag      240

aaagaaagga aaaccacaga aatgcaaagt ccaatgcagc cagtggacca agcgagcctt      300

ccaggtcact gcagggaacc tccaccatgg gaaaatgaag ccacagagag aatttatcat      360

ttcgtggtgg ggcagatggt ttattatcag tgcgtccagg gatacagggc tctacacaga      420

ggtcctgctg agagcgtctg caaaatgacc cacgggaaga caaggtggac ccagccccag      480

ctcatatgca caggtgaaat ggagaccagt cagtttccag gtgaagagaa gcctcaggca      540

agccccgaag gccgtcctga gagtgagact tcctgcctcg tcacaacaac agattttcaa      600

atacagacag aaatggctgc aaccatggag acgtccatat ttacaacaga gtaccag         657


<210>  3783
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  3783
gcggtgaatg gcacttccca gttcacatgc ttctacaact cgagagccaa catctcctgt       60

gtctggagcc aagatggggc tctgcaggac acttcctgcc aagtccatgc ctggccggac      120

agacggcggt ggaaccaaac ctgtgagctg ctccccgtga gtcaagcatc ctgggcctgc      180

aacctgatcc tcggagcccc agattctcag aaactgacca cagttgacat cgtcaccctg      240

agggtgctgt gccgtgaggg ggtgcgatgg agggtgatgg ccatccagga cttcaagccc      300

tttgagaacc ttcgcctgat ggcccccatc tccctccaag ttgtccacgt ggagacccac      360

agatgcaaca taagctggga aatctcccaa gcctcccact actttgaaag acacctggag      420

ttcgaggccc ggacgctgtc cccaggccac acctgggagg aggcccccct gctgactctc      480

aagcagaagc aggaatggat ctgcctggag acgctcaccc cagacaccca gtatgagttt      540

caggtgcggg tcaagcctct gcaaggcgag ttcacgacct ggagcccctg gagccagccc      600

ctggccttca ggacaaagcc tgcagccctt gggaaggaca cc                         642


<210>  3784
<211>  720
<212>  DNA
<213>  Homo Sapiens

<400>  3784
ctgaacacga caattctgac gcccaatggg aatgaagaca ccacagctga tttcttcctg       60

accactatgc ccactgactc cctcagtgtt tccactctgc ccctcccaga ggttcagtgt      120

tttgtgttca atgtcgagta catgaattgc acttggaaca gcagctctga gccccagcct      180

accaacctca ctctgcatta ttggtacaag aactcggata atgataaagt ccagaagtgc      240

agccactatc tattctctga agaaatcact tctggctgtc agttgcaaaa aaaggagatc      300

cacctctacc aaacatttgt tgttcagctc caggacccac gggaacccag gagacaggcc      360

acacagatgc taaaactgca gaatctggtg atcccctggg ctccagagaa cctaacactt      420

cacaaactga gtgaatccca gctagaactg aactggaaca acagattctt gaaccactgt      480

ttggagcact tggtgcagta ccggactgac tgggaccaca gctggactga acaatcagtg      540

gattatagac ataagttctc cttgcctagt gtggatgggc agaaacgcta cacgtttcgt      600

gttcggagcc gctttaaccc actctgtgga agtgctcagc attggagtga atggagccac      660

ccaatccact gggggagcaa tacttcaaaa gagaatcctt tcctgtttgc attggaagcc      720


<210>  3785
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  3785
gctcccatga cccagacaac gcccttgaag acaagctggg ttaactgctc taacatgatc       60

gatgaaatta taacacactt aaagcagcca cctttgcctt tgctggactt caacaacctc      120

aatggggaag accaagacat tctgatggaa aataaccttc gaaggccaaa cctggaggca      180

ttcaacaggg ctgtcaagag tttacagaac gcatcagcaa ttgagagcat tcttaaaaat      240

ctcctgccat gtctgcccct ggccacggcc gcacccacgc gacatccaat ccatatcaag      300

gacggtgact ggaatgaatt ccggaggaaa ctgacgttct atctgaaaac ccttgagaat      360

gcgcaggctc aacagacgac tttgagcctc gcgatcttt                             399


<210>  3786
<211>  423
<212>  DNA
<213>  Homo Sapiens

<400>  3786
tcccacacgt tgcccgtccg tttactacga ccaagtgatg atgtacagaa aatagtcgag       60

gaattacagt ccctctcgaa gatgcttttg aaagatgtgg aggaagagaa gggcgtgctc      120

gtgtcccaga attacacgct gccgtgtctc agccctgacg cccagccgcc aaacaacatc      180

cacagcccag ccatccgggc atatctcaag acaatcagac agctagacaa caaatctgtt      240

attgatgaga tcatagagca cctcgacaaa ctcatatttc aagatgcacc agaaacaaac      300

atttctgtgc caacagacac ccatgaatgt aaacgcttca tcctgactat ttctcaacag      360

ttttcagagt gcatggacct cgcactaaaa tcattgacct ctggagccca acaggccacc      420

act                                                                    423


<210>  3787
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  3787
tctctgccag ctaagcctga gaacatttcc tgtgtctact actataggaa aaatttaacc       60

tgcacttgga gtccaggaaa ggaaaccagt tatacccagt acacagttaa gagaacttac      120

gcttttggag aaaaacatga taattgtaca accaatagtt ctacaagtga aaatcgtgct      180

tcgtgctctt ttttccttcc aagaataacg atcccagata attataccat tgaggtggaa      240

gctgaaaatg gagatggtgt aattaaatct catatgacat actggagatt agagaacata      300

gcgaaaactg aaccacctaa gattttccgt gtgaaaccag ttttgggcat caaacgaatg      360

attcaaattg aatggataaa gcctgagttg gcgcctgttt catctgattt aaaatacaca      420

cttcgattca ggacagtcaa cagtaccagc tggatggaag tcaacttcgc taagaaccgt      480

aaggataaaa accaaacgta caacctcacg gggctgcagc cttttacaga atatgtcata      540

gctctgcgat gtgcggtcaa ggagtcaaag ttctggagtg actggagcca agaaaaaatg      600

ggaatgactg aggaagaagc tccatgtggc ctggaactgt ggagagtcct gaaaccagct      660

gaggcggatg gaagaaggcc agtgcggttg ttatggaaga aggcaagagg agccccagtc      720

ctagagaaaa cacttggcta caacatatgg tactatccag aaagcaacac taacctcaca      780

gaaacaatga acactactaa ccagcagctt gaactgcatc tgggaggcga gagcttttgg      840

gtgtctatga tttcttataa ttctcttggg aagtctccag tggccaccct gaggattcca      900

gctattcaag aaaaatcatt tcagtgcatt gaggtcatgc aggcctgcgt tgctgaggac      960

cagctagtgg tgaagtggca aagctctgct ctagacgtga acacttggat gattgaatgg     1020

tttccggatg tggactcaga gcccaccacc ctttcctggg aatctgtgtc tcaggccacg     1080

aactggacga tccagcaaga taaattaaaa cctttctggt gctataacat ctctgtgtat     1140

ccaatgttgc atgacaaagt tggcgagcca tattccatcc aggcttatgc caaagaaggc     1200

gttccatcag aaggtcctga gaccaaggtg gagaacattg gcgtgaagac ggtcacgatc     1260

acatggaaag agattcccaa gagtgagaga aagggtatca tctgcaacta caccatcttt     1320

taccaagctg aaggtggaaa aggattctcc aagacagtca attccagcat cttgcagtac     1380

ggcctggagt ccctgaaacg aaagacctct tacattgttc aggtcatggc cagcaccagt     1440

gctgggggaa ccaacgggac cagcataaat ttcaagacat tgtcattcag tgtctttgag     1500


<210>  3788
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  3788
gcctgggtct cagcgtgtga cactgaggac actgtgggac acctgggacc ctggagggac       60

aaggatccgg ccctttggtg ccaactctgc ctctcttcac agcaccaggc catagaaaga      120

ttttatgata aaatgcaaaa tgcagaatca ggacgtggac aggtgatgtc gagcctggca      180

gagctggagg acgacttcaa agagggctac ctggagacag tggcggctta ttatgaggag      240

cagcacccag agctcactcc tctacttgaa aaagaaagag atggattacg gtgccgaggc      300

aacagatccc ctgtcccgga tgttgaggat cccgcaaccg aggagcctgg ggagagcttt      360

tgtgacaagg tcatgagatg gttccaggcc atgctgcagc ggctgcagac ctggtggcac      420

ggggttctgg cctgggtgaa ggagaaggtg gtggccctgg tccatgcagt gcaggccctc      480

tggaaacagt tccagagttt ctgctgctct ctgtcagagc tcttcatgtc ctctttccag      540

tcctacggag ccccacgggg ggacaaggag gagctgacac cccagaagtg ctctgaaccc      600

caatcttcaa aa                                                          612


<210>  3789
<211>  810
<212>  DNA
<213>  Homo Sapiens

<400>  3789
atgaagccta aaatgaagta ttcaaccaac aaaatttcca cagcaaagtg gaagaacaca       60

gcaagcaaag ccttgtgttt caagctggga aaatcccaac agaaggccaa agaagtttgc      120

cccatgtact ttatgaagct ccgctctggc cttatgataa aaaaggaggc ctgttacttt      180

aggagagaaa ccaccaaaag gccttcactg aaaacaggta gaaagcacaa aagacatctg      240

gtactcgctg cctgtcaaca gcagtctact gtggagtgct ttgcctttgg tatatcaggg      300

gtccagaaat atactagagc acttcatgat tcaagtatca caggaatttc acctattaca      360

gagtatcttg cttctctaag cacatacaat gatcaatcca ttacttttgc tttggaggat      420

gaaagttatg agatatatgt tgaagacttg aaaaaagatg aaaagaaaga taaggtgtta      480

ctgagttact atgagtctca acacccctca aatgaatcag gtgacggtgt tgatggtaag      540

atgttaatgg taaccctgag tcctacaaaa gacttctggt tgcatgccaa caacaaggaa      600

cactctgtgg agctccataa gtgtgaaaaa ccactgccag accaggcctt ctttgtcctt      660

cataatatgc actccaactg tgtttcattt gaatgcaaga ctgatcctgg agtgtttata      720

ggtgtaaagg ataatcatct tgctctgatt aaagtagact cttctgagaa tttgtgtact      780

gaaaatatct tgtttaagct ctctgaaact                                       810


<210>  3790
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  3790
aatgagcctt tggagatgtg gcccttgacg cagaatgagg agtgcactgt cacgggtttt       60

ctgcgggaca agctgcagta caggagccga cttcagtaca tgaaacacta cttccccatc      120

aactacaaga tcagtgtgcc ttacgagggg gtgttcagaa tcgccaacgt caccaggctg      180

cagagggccc aggtgagcga gcgggagctg cggtatctgt gggtcttggt gagcctcagt      240

gccactgagt cggtgcagga cgtgctgctc gagggccacc catcctggaa gtacctgcag      300

gaggtgcaga cgctgctgct gaatgtccag cagggcctca cggatgtgga ggtcagcccc      360

aaggtggaat ccgtgttgtc cctcttgaat gccccagggc caaacctgaa gctggtgcgg      420

cccaaagccc tgctggacaa ctgcttccgg gtcatggagc tgctgtactg ctcctgctgt      480

aaacaaagct ccgtcctaaa ctggcaggac tgtgaggtgc caagtcctca gtcttgcagc      540

ccagagccct cattgcagta tgcggccacc cagctgtacc ctccgccccc gtggtccccc      600

agctccccgc ctcactccac gggctcggtg aggccggtca gggcacaggg cgagggcctc      660

ttgccc                                                                 666


<210>  3791
<211>  459
<212>  DNA
<213>  Homo Sapiens

<400>  3791
cgggaggcag cacccaaatc ctatgctatt cgtgattctc gacagatggt gtgggtcctg       60

agtggaaatt ctttaatagc agctcctctt agccgcagca ttaagcctgt cactcttcat      120

ttaatagcct gtagagacac agaattcagt gacaaggaaa agggtaatat ggtttacctg      180

ggaatcaagg gaaaagatct ctgtctcttc tgtgcagaaa ttcagggcaa gcctactttg      240

cagcttaagg aaaaaaatat catggacctg tatgtggaga agaaagcaca gaagcccttt      300

ctctttttcc acaataaaga aggctccact tctgtctttc agtcagtctc ttaccctggc      360

tggttcatag ccacctccac cacatcagga cagcccatct ttctcaccaa ggagagaggc      420

ataactaata acactaactt ctacttagat tctgtggaa                             459


<210>  3792
<211>  861
<212>  DNA
<213>  Homo Sapiens

<400>  3792
acgaaggaag atccaaaccc accaatcacg aacctaagga tgaaagcaaa ggctcagcag       60

ttgacctggg accttaacag aaatgtgacc gatatcgagt gtgttaaaga cgccgactat      120

tctatgccgg cagtgaacaa tagctattgc cagtttggag caatttcctt atgtgaagtg      180

accaactaca ccgtccgagt ggccaaccca ccattctcca cgtggatcct cttccctgag      240

aacagtggga agccttgggc aggtgcggag aatctgacct gctggattca tgacgtggat      300

ttcttgagct gcagctgggc ggtaggcccg ggggcccccg cggacgtcca gtacgacctg      360

tacttgaacg ttgccaacag gcgtcaacag tacgagtgtc ttcactacaa aacggatgct      420

cagggaacac gtatcgggtg tcgtttcgat gacatctctc gactctccag cggttctcaa      480

agttcccaca tcctggtgcg gggcaggagc gcagccttcg gtatcccctg cacagataag      540

tttgtcgtct tttcacagat tgagatatta actccaccca acatgactgc aaagtgtaat      600

aagacacatt cctttatgca ctggaaaatg agaagtcatt tcaatcgcaa atttcgctat      660

gagcttcaga tacaaaagag aatgcagcct gtaatcacag aacaggtcag agacagaacc      720

tccttccagc tactcaatcc tggaacgtac acagtacaaa taagagcccg ggaaagagtg      780

tatgaattct tgagcgcctg gagcaccccc cagcgcttcg agtgcgacca ggaggagggc      840

gcaaacacac gtgcctggcg g                                                861


<210>  3793
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  3793
cacaagtgcg atatcacctt acaggagatc atcaaaactt tgaacagcct cacagagcag       60

aagactctgt gcaccgagtt gaccgtaaca gacatctttg ctgcctccaa gaacacaact      120

gagaaggaaa ccttctgcag ggctgcgact gtgctccggc agttctacag ccaccatgag      180

aaggacactc gctgcctggg tgcgactgca cagcagttcc acaggcacaa gcagctgatc      240

cgattcctga aacggctcga caggaacctc tggggcctgg cgggcttgaa ttcctgtcct      300

gtgaaggaag ccaaccagag tacgttggaa aacttcttgg aaaggctaaa gacgatcatg      360

agagagaaat attcaaagtg ttcgagc                                          387


<210>  3794
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  3794
atgaaggtct tgcaggagcc cacctgcgtc tccgactaca tgagcatctc tacttgcgag       60

tggaagatga atggtcccac caattgcagc accgagctcc gcctgttgta ccagctggtt      120

tttctgctct ccgaagccca cacgtgtgtc cctgagaaca acggaggcgc ggggtgcgtg      180

tgccacctgc tcatggatga cgtggtcagt gcggataact atacactgga cctgtgggct      240

gggcagcagc tgctgtggaa gggctccttc aagcccagcg agcatgtgaa acccagggcc      300

ccaggaaacc tgacagttca caccaatgtc tccgacactc tgctgctgac ctggagcaac      360

ccgtatcccc ctgacaatta cctgtataat catctcacct atgcagtcaa catttggagt      420

gaaaacgacc cggcagattt cagaatctat aacgtgacct acctagaacc ctccctccgc      480

atcgcagcca gcaccctgaa gtctgggatt tcctacaggg cacgggtgag ggcctgggct      540

cagtgctata acaccacctg gagtgagtgg agccccagca ccaagtggca caactcctac      600

agggagccct tcgagcagca c                                                621


<210>  3795
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  3795
atccccacag aaattcccac aagtgcattg gtgaaagaga ccttggcact gctttctact       60

catcgaactc tgctgatagc caatgagact ctgaggattc ctgttcctgt acataaaaat      120

caccaactgt gcactgaaga aatctttcag ggaataggca cactggagag tcaaactgtg      180

caagggggta ctgtggaaag actattcaaa aacttgtcct taataaagaa atacattgac      240

ggccaaaaaa aaaagtgtgg agaagaaaga cggagagtaa accaattcct agactacctg      300

caagagtttc ttggtgtaat gaacaccgag tggataatag aaagt                      345


<210>  3796
<211>  945
<212>  DNA
<213>  Homo Sapiens

<400>  3796
gacttacttc ctgatgaaaa gatttcactt ctcccgcctg tcaatttcac cattaaagtt       60

actggtttgg ctcaagttct tttacaatgg aaaccaaatc ctgatcaaga gcaaaggaat      120

gttaatctag aatatcaagt gaaaataaac gctccaaaag aagatgacta tgaaaccaga      180

atcactgaaa gcaaatgtgt aaccatcctc cacaagggct tttcagcaag tgtgcggacc      240

atcctgcaga acgaccactc actactggcc agcagctggg cttctgctga acttcatgcc      300

ccaccagggt ctcctggaac ctcaattgtg aatttaactt gcaccacaaa cactacagaa      360

gacaattatt cacgtttaag gtcataccaa gtttcccttc actgcacctg gcttgttggc      420

acagatgccc ctgaggacac gcagtatttt ctctactata ggtatggctc ttggactgaa      480

gaatgccaag aatacagcaa agacacactg gggagaaata tcgcatgctg gtttcccagg      540

acttttatcc tcagcaaagg gcgtgactgg cttgcggtgc ttgttgacgg ctccagcaag      600

cactctgcta tcaggccctt tgatcagctg tttgcccttc acgccattga tcaaataaat      660

cctccactga atgtcacagc agagattgaa ggaactcgtc tctctatcca atgggagaaa      720

ccagtgtctg cttttccaat ccattgcttt gattatgaag taaaaataca caatacaagg      780

aatggatatt tgcagataga aaaattgatg accaatgcat tcatctcaat aattgatgat      840

ctttctaagt acgatgttca agtgagagca gcagtgagct ccatgtgcag agaggcaggg      900

ctctggagtg agtggagcca acctatttat gtggggttct caaga                      945


<210>  3797
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3797
gtacccccag gagaagattc caaagatgta gccgccccac acagacagcc actcacctct       60

tcagaacgaa ttgacaaaca aattcggtac atcctcgacg gcatctcagc cctgagaaag      120

gagacatgta acaagagtaa catgtgtgaa agcagcaaag aggcactggc agaaaacaac      180

ctgaaccttc caaagatggc tgaaaaagat ggatgcttcc aatctggatt caatgaggag      240

acttgcctgg tgaaaatcat cactggtctt ttggagtttg aggtatacct agagtacctc      300

cagaacagat ttgagagtag tgaggaacaa gccagagctg tgcagatgag tacaaaagtc      360

ctgatccagt tcctgcagaa aaaggcaaag aatctagatg caataaccac ccctgaccca      420

accacaaatg ccagcctgct gacgaagctg caggcacaga accagtggct gcaggacatg      480

acaactcatc tcattctgcg cagctttaag gagttcctgc agtccagcct gagggctctt      540

cggcaaatg                                                              549


<210>  3798
<211>  1038
<212>  DNA
<213>  Homo Sapiens

<400>  3798
ctggccccaa ggcgctgccc tgcgcaggag gtggcgagag gcgtgctgac cagtctgcca       60

ggagacagcg tgactctgac ctgcccgggg gtagagccgg aagacaatgc cactgttcac      120

tgggtgctca ggaagccggc tgcaggctcc caccccagca gatgggctgg catgggaagg      180

aggctgctgc tgaggtcggt gcagctccac gactctggaa actattcatg ctaccgggcc      240

ggccgcccag ctgggactgt gcacttgctg gtggatgttc cccccgagga gccccagctc      300

tcctgcttcc ggaagagccc cctcagcaat gttgtttgtg agtggggtcc tcggagcacc      360

ccatccctga cgacaaaggc tgtgctcttg gtgaggaagt ttcagaacag tccggccgaa      420

gacttccagg agccgtgcca gtattcccag gagtcccaga agttctcctg ccagttagca      480

gtcccggagg gagacagctc tttctacata gtgtccatgt gcgtcgccag tagtgtcggg      540

agcaagttca gcaaaactca aacctttcag ggttgtggaa tcttgcagcc tgatccgcct      600

gccaacatca cagtcactgc cgtggccaga aacccccgct ggctcagtgt cacctggcaa      660

gacccccact cctggaactc atctttctac agactacggt ttgagctcag atatcgggct      720

gaacggtcaa agacattcac aacatggatg gtcaaggacc tccagcatca ctgtgtcatc      780

cacgacgcct ggagcggcct gaggcacgtg gtgcagcttc gtgcccagga ggagttcggg      840

caaggcgagt ggagcgagtg gagcccggag gccatgggca cgccttggac agaatccagg      900

agtcctccag ctgagaacga ggtgtccacc cccatgcagg cacttactac taataaagac      960

gatgataata ttctcttcag agattctgca aatgcgacaa gcctcccagt gcaagattct     1020

tcttcagtac cactgccc                                                   1038


<210>  3799
<211>  1791
<212>  DNA
<213>  Homo Sapiens

<400>  3799
gaacttctag atccatgtgg ttatatcagt cctgaatctc cagttgtaca acttcattct       60

aatttcactg cagtttgtgt gctaaaggaa aaatgtatgg attattttca tgtaaatgct      120

aattacattg tctggaaaac aaaccatttt actattccta aggagcaata tactatcata      180

aacagaacag catccagtgt cacctttaca gatatagctt cattaaatat tcagctcact      240

tgcaacattc ttacattcgg acagcttgaa cagaatgttt atggaatcac aataatttca      300

ggcttgcctc cagaaaaacc taaaaatttg agttgcattg tgaacgaggg gaagaaaatg      360

aggtgtgagt gggatcgtgg aagggaaaca cacttggaga caaacttcac tttaaaatct      420

gaatgggcaa cacacaagtt tgctgattgc aaagcaaaac gtgacacccc cacctcatgc      480

actgttgatt attctactgt gtattttgtc aacattgaag tctgggtaga agcagagaat      540

gcccttggga aggttacatc agatcatatc aattttgatc ctgtatataa agtgaagccc      600

aatccgccac ataatttatc agtgatcaac tcagaggaac tgtctagtat cttaaaattg      660

acatggacca acccaagtat taagagtgtt ataatactaa aatataacat tcaatatagg      720

accaaagatg cctcaacttg gagccagatt cctcctgaag acacagcatc cacccgatct      780

tcattcactg tccaagacct taaacctttt acagaatatg tgtttaggat tcgctgtatg      840

aaggaagatg gtaagggata ctggagtgac tggagtgaag aagcaagtgg gatcacctat      900

gaagatagac catctaaagc accaagtttc tggtataaaa tagatccatc ccatactcaa      960

ggctacagaa ctgtacaact cgtgtggaag acattgcctc cttttgaagc caatggaaaa     1020

atcttggatt atgaagtgac tctcacaaga tggaaatcac atttacaaaa ttacacagtt     1080

aatgccacaa aactgacagt aaatctcaca aatgatcgct atgtagcaac cctaacagta     1140

agaaatcttg ttggcaaatc agatgcagct gttttaacta tccctgcctg tgactttcaa     1200

gctactcacc ctgtaatgga tcttaaagca ttccccaaag ataacatgct ttgggtggaa     1260

tggactactc caagggaatc tgtaaagaaa tatatacttg agtggtgtgt gttatcagat     1320

aaagcaccct gtatcacaga ctggcaacaa gaagatggta ccgtgcatcg cacctattta     1380

agagggaact tagcagagag caaatgctat ttgataacag ttactccagt atatgctgat     1440

ggaccaggaa gccctgaatc cataaaggca taccttaaac aagctccacc ttccaaagga     1500

cctactgttc ggacaaaaaa agtagggaaa aacgaagctg tcttagagtg ggaccaactt     1560

cctgttgatg ttcagaatgg atttatcaga aattatacta tattttatag aaccatcatt     1620

ggaaatgaaa ctgctgtgaa tgtggattct tcccacacag aatatacatt gtcctctttg     1680

actagtgaca cattgtacat ggtacgaatg gcagcataca cagatgaagg tgggaaggat     1740

ggtccagaat tcacttttac taccccaaag tttgctcaag gagaaattga a              1791


<210>  3800
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  3800
gattgtgata ttgaaggtaa agatggcaaa caatatgaga gtgttctaat ggtcagcatc       60

gatcaattat tggacagcat gaaagaaatt ggtagcaatt gcctgaataa tgaatttaac      120

ttttttaaaa gacatatctg tgatgctaat aaggaaggta tgtttttatt ccgtgctgct      180

cgcaagttga ggcaatttct taaaatgaat agcactggtg attttgatct ccacttatta      240

aaagtttcag aaggcacaac aatactgttg aactgcactg gccaggttaa aggaagaaaa      300

ccagctgccc tgggtgaagc ccaaccaaca aagagtttgg aagaaaataa atctttaaag      360

gaacagaaaa aactgaatga cttgtgtttc ctaaagagac tattacaaga gataaaaact      420

tgttggaata aaattttgat gggcactaaa gaacac                                456


<210>  3801
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3801
gaaagtggct atgctcaaaa tggagacttg gaagatgcag aactggatga ctactcattc       60

tcatgctata gccagttgga agtgaatgga tcgcagcact cactgacctg tgcttttgag      120

gacccagatg tcaacatcac caatctggaa tttgaaatat gtggggccct cgtggaggta      180

aagtgcctga atttcaggaa actacaagag atatatttca tcgagacaaa gaaattctta      240

ctgattggaa agagcaatat atgtgtgaag gttggagaaa agagtctaac ctgcaaaaaa      300

atagacctaa ccactatagt taaacctgag gctccttttg acctgagtgt cgtctatcgg      360

gaaggagcca atgactttgt ggtgacattt aatacatcac acttgcaaaa gaagtatgta      420

aaagttttaa tgcacgatgt agcttaccgc caggaaaagg atgaaaacaa atggacgcat      480

gtgaatttat ccagcacaaa gctgacactc ctgcagagaa agctccaacc ggcagcaatg      540

tatgagatta aagttcgatc catccctgat cactatttta aaggcttctg gagtgaatgg      600

agtccaagtt attacttcag aactccagag atcaataata gctcagggga gatggat         657


<210>  3802
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  3802
gcagttttgc caaggagtgc taaagaactt agatgtcagt gcataaagac atactccaaa       60

cctttccacc ccaaatttat caaagaactg agagtgattg agagtggacc acactgcgcc      120

aacacagaaa ttattgtaaa gctttctgat ggaagagagc tctgtctgga ccccaaggaa      180

aactgggtgc agagggttgt ggagaagttt ttgaagaggg ctgagaattc a               231


<210>  3803
<211>  144
<212>  DNA
<213>  Homo Sapiens

<400>  3803
atggaagatt ttaacatgga gagtgacagc tttgaagatt tctggaaagg tgaagatctt       60

agtaattaca gttacagctc taccctgccc ccttttctac tagatgccgc cccatgtgaa      120

ccagaatccc tggaaatcaa caag                                             144


<210>  3804
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  3804
caggggtgtc caaccttggc ggggatcctg gacatcaact tcctcatcaa caagatgcag       60

gaagatccag cttccaagtg ccactgcagt gctaatgtga ccagttgtct ctgtttgggc      120

attccctctg acaactgcac cagaccatgc ttcagtgaga gactgtctca gatgaccaat      180

accaccatgc aaacaagata cccactgatt ttcagtcggg tgaaaaaatc agttgaagta      240

ctaaagaaca acaagtgtcc atatttttcc tgtgaacagc catgcaacca aaccacggca      300

ggcaacgcgc tgacatttct gaagagtctt ctggaaattt tccagaaaga aaagatgaga      360

gggatgagag gcaagata                                                    378


<210>  3805
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  3805
tctgtcacag gggaaggaca agggccaagg tctagaacct tcacctgcct caccaacaac       60

attctcagga tcgattgcca ctggtctgcc ccagagctgg gacagggctc cagcccctgg      120

ctcctcttca ccaggctcct ggcggcacac ataagtgcat cttgcggggc agtgagtgca      180

ccgtcgtgct gccacctgag gcagtgctcg tgccatctga caatttcacc atcactttcc      240

accactgcat gtctgggagg gagcaggtca gcctggtgga cccggagtac ctgccccgga      300

gacacgagca acatcagttc tggccactgc atcctgacct ggagcatcag tcctgccttg      360

gagccaatga ccacacttct cagctatgag ctggccttca agaagcagga agaggcctgg      420

gagcaggccc agcacaggga tcacattgtc ggggtgacct ggcttatact tgaagccttt      480

gagctggacc ctggctttat ccatgaggcc aggctgcgtg tccagatggc cacactggag      540

gatgatgtgg tagaggagga gcgttataca ggccagtgga gtgagtggag ccagcctgtg      600

tgcttccagg ctccccagag acaaggccct ctgatcccac cctgggggtg gcca            654


<210>  3806
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  3806
ttgcttgtga cggtccagca cacagaacgc tatgtcaccc tgtttgcctc tatcatcctc       60

aaatgtgact acaccacctc tgcccagctc caggacgtgg tggtgacatg gcgcttcaag      120

tccttctgca aggaccctat ctttgactac tactcagcgt cataccaggc agctttatcc      180

ctgggccagg acccatccaa tgactgcaac gacaaccagc gggaagttcg catagtggcc      240

cagcggcggg ggcagaatga gcccgtgctg ggggtagatt accggcagcg caagatcacc      300

atccagaacc gagcagatct cgtgataaat gaagtgatgt ggtgggacca tggagtgtat      360

tactgcacca ttgaggctcc aggggacaca tcaggagacc ccgataagga agtaaagctc      420

atcgtcctac ac                                                          432


<210>  3807
<211>  2583
<212>  DNA
<213>  Homo Sapiens

<400>  3807
ggtgaacaga ttgcagaatt cagtatccac cttttgggga agcagtacag ggaagaacta       60

caggattcct ccagctttca ccaccagcac cttgaagaag aatttatttc agaggttgaa      120

aatgcattta ctgggttacc aggctacaag gaaattcgtg tacttgaatt taggtccccc      180

aaggaaaatg acagtggcgt agatgtttac tatgcagtta ccttcaatgg tgaggccatc      240

agcaatacca cctgggacct cattagcctt cactccaaca aggtggaaaa ccatggcctt      300

gtggaactgg atgataaacc cactgttgtt tatacaatca gtaacttcag agattatatt      360

gctgagacat tgcagcagaa ttttttgctg gggaactctt ccttgaatcc agatcctgat      420

tccctgcagc ttatcaatgt gagaggagtt ttgcgtcacc aaactgaaga tctagtttgg      480

aacacccaaa gttcaagtct tcaggcaacg ccgtcatcta ttctggataa tacctttcaa      540

gctgcatggc cctcagcaga tgaatccatc accagcagta ttccaccact tgatttcagc      600

tctggtcctc cctcagccac tggcagggaa ctctggtcag aaagtccttt gggtgattta      660

gtgtctacac acaaattagc ctttccctcg aagatgggcc tcagctcttc cccagaggtt      720

ttagaggtta gcagcttgac tcttcattct gtcaccccgg cagtgcttca gactggcttg      780

cctgtggctt ctgaggaaag gacttctgga tctcacttgg tagaagatgg attagccaat      840

gttgaagagt cagaagattt tctttctatt gattcattgc cttcaagttc attcactcaa      900

cctgtgccaa aagaaacaat accatccatg gaagactctg atgtgtcctt aacatcttca      960

ccatatctga cctcttctat accttttggc ttggactcct tgacctccaa agtcaaagac     1020

caattaaaag tgagcccttt cctgccagat gcatccatgg aaaaagagtt aatatttgac     1080

ggtggtttag gttcagggtc tgggcaaaag gtagatctga ttacttggcc acggagtgag     1140

acttcatcag agaagagcgc tgaaccactg tccaagccgt ggcttgaaga tgatgattca     1200

cttttgccag ctgagattga agacaagaaa ctagttttag ttgacaaaat ggattccaca     1260

gaccaaatta gtaagcactc aaaatatgaa catgatgaca gatccataca ctttccagag     1320

gaagagcctc ttagtgggcc tgctgtgccc atcttcgcag atactgcagc tgaatctgcg     1380

tctctaaccc tccccaagca catatcagaa gtacctggtg ttgatgatta ctcagttacc     1440

aaagcacctc ttatactgac atctgtagca atctctgcct ctactgataa atcagatcag     1500

gcagatgcca tcctaaggga ggatatggaa caaattactg agtcatccaa ctatgaatgg     1560

tttgacagtg aggtttcaat ggtaaagcca gatatgcaaa ctttgtggac tatattgcca     1620

gaatcagaga gagtttggac aagaacttct tccctagaga aattgtccag agacatattg     1680

gcaagtacac cacagagtgc tgacaggctc tggttatctg tgacacagtc taccaaattg     1740

cctccaacca caatctccac cctgctagag gatgaagtaa ttatgggtgt acaggatatt     1800

tcgttagaac tggaccggat aggcacagat tactatcagc ctgagcaagt ccaagagcaa     1860

aatggcaagg ttggtagtta tgtggaaatg tcaacaagtg ttcactccac agagatggtt     1920

agtgtggctt ggcccacaga aggaggagat gacttgagtt atacccagac ttcaggagct     1980

ttggtggttt tcttcagcct ccgagtgact aacatgatgt tttcagaaga tctgtttaat     2040

aaaaactcct tggagtataa agccctggag caaagattct tagaattgct ggttccctat     2100

ctccagtcaa atctcacggg gttccagaac ttagaaatcc tcaacttcag aaatggcagc     2160

attgtggtga acagtcgaat gaagtttgcc aattctgtcc ctcctaacgt caacaatgcg     2220

gtgtacatga ttctggaaga cttttgtacc actgcctaca ataccatgaa cttggctatt     2280

gataaatact ctcttgatgt ggaatcaggt gatgaagcca acccttgcaa gtttcaggcc     2340

tgtaatgaat tttcagagtg tctggtcaac ccctggagtg gagaagcaaa gtgcagatgc     2400

ttccctggat acctgagtgt ggaagaacgg ccctgtcaga gtctctgtga cctacagcct     2460

gacttctgct tgaatgatgg aaagtgtgac attatgcctg ggcacggggc catttgtagg     2520

tgccgggtgg gtgagaactg gtggtaccga ggcaagcact gtgaggaatt tgtgtctgag     2580

ccc                                                                   2583


<210>  3808
<211>  474
<212>  DNA
<213>  Homo Sapiens

<400>  3808
gcagccccca gaaggtgtct attatctcat tatcgttcct tagagccccg tacgcttgca       60

gcggccaaag cacttcgtga caggtatgaa gaagaggcat tatcttgggg acaaaggaat      120

tgtagctttc gtcctcgtag agacccaccc cgtccttcaa gttgcgccag gctaagacac      180

gtagcgcgtg gcatcgccga tgctcaagcg gttctatcag gcttacatag atcagagctt      240

cttccaggag ccggcccaat tctggagcta cttgcggcgg cgggaagaga cgtggctgcg      300

tgcctggagt tagcaagacc aggctcaagt aggaaagtcc ccggtgccca gaaacgtcgt      360

cataagccca ggagagcaga ctcaccaaga tgtaggaaag cttcagtagt ctttaatcta      420

ctgaggctac ttacgtggga attacgtctg gccgcccact ctggcccgtg tctg            474


<210>  3809
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  3809
tttgtgaacc aacacctgtg cggctcacac ctggtggaag ctctctacct agtgtgcggg       60

gaacgaggct tcttctacac acccaagacc cgccgggagg cagaggacct gcaggtgggg      120

caggtggagc tgggcggggg ccctggtgca ggcagcctgc agcccttggc cctggagggg      180

tccctgcaga agcgtggcat tgtggaacaa tgctgtacca gcatctgctc cctctaccag      240

ctggagaact actgcaac                                                    258


<210>  3810
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  3810
ttgggccccg cgcccacccc agagatgcgt gagaagttgt gcggccacca cttcgtacgc       60

gcgctagtgc gcgtgtgcgg gggcccccgc tggtccaccg aagccaggag gcctgcggcc      120

ggaggcgacc gtgagttgct acagtggctg gagagacgac atctgctcca tgggctggtg      180

gccgacagta atctcacgct gggacctggc ctgcagcccc tgccccagac ctctcaccat      240

caccgccacc accgtgcagc tgccaccaac cctgcacgct actgctgcct cagtggctgt      300

acccaacaag acctgctgac cctctgtccc tac                                   333


<210>  3811
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  3811
aaggagtctg tgagactctg tgggctagaa tacatacgga cagtcatcta tatctgtgct       60

agctccaggt ggagaaggca tctggagggg atccctcaag ctcagcaagc tgagacagga      120

aactccttcc agctcccaca taaacgtgag ttttctgagg aaaatccagc gcaaaacctt      180

ccgaaggtgg atgcctcagg ggaagaccgt ctttggggtg gacagatgcc cactgaagag      240

ctttggaagt caaagaagca ttcagtgatg tcaagacaag atttacaaac tttgtgttgc      300

actgatggct gttccatgac tgatttgagt gctctttgc                             339


<210>  3812
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  3812
cgtgaactga gcgacatcag cagtgccagg aagctgtgcg gcaggtactt ggtgaaagaa       60

atagaaaaac tctgcggcca tgccaactgg agccagttcc gtttcgagga ggaaacccct      120

ttctcacggt tgattgcaca ggcctcggag aaggtcgaag cctacagccc ataccagttc      180

gaaagcccgc aaaccgcttc cccggcccgg ggaagaggca caaacccagt gtctacttct      240

tgggaagaag cagtaaacag ttgggaaatg cagtcactac ctgagtataa ggataaaaag      300

ggatattcac cccttggtaa gacaagagaa ttttcttcat cacataatat caatgtatat      360

attcatgaga atgcaaaatt tcagaagaaa cgtagaaaca aaattaaaac cttaagcaat      420

ttgttttggg ggcatcatcc ccaaagaaaa cgcagaggat attcagaaaa gtgttgtctt      480

acaggatgta caaaagaaga acttagcatt gcatgtcttc catatattga tttt            534


<210>  3813
<211>  2157
<212>  DNA
<213>  Homo Sapiens

<400>  3813
cacctgtacc ccggagaggt gtgtcccggc atggatatcc ggaacaacct cactaggttg       60

catgagctgg agaattgctc tgtcatcgaa ggacacttgc agatactctt gatgttcaaa      120

acgaggcccg aagatttccg agacctcagt ttccccaaac tcatcatgat cactgattac      180

ttgctgctct tccgggtcta tgggctcgag agcctgaagg acctgttccc caacctcacg      240

gtcatccggg gatcacgact gttctttaac tacgcgctgg tcatcttcga gatggttcac      300

ctcaaggaac tcggcctcta caacctgatg aacatcaccc ggggttctgt ccgcatcgag      360

aagaacaatg agctctgtta cttggccact atcgactggt cccgtatcct ggattccgtg      420

gaggataatt acatcgtgtt gaacaaagat gacaacgagg agtgtggaga catctgtccg      480

ggtaccgcga agggcaagac caactgcccc gccaccgtca tcaacgggca gtttgtcgaa      540

cgatgttgga ctcatagtca ctgccagaaa gtttgcccga ccatctgtaa gtcacacggc      600

tgcaccgccg aaggcctctg ttgccacagc gagtgcctgg gcaactgttc tcagcccgac      660

gaccccacca agtgcgtggc ctgccgcaac ttctacctgg acggcaggtg tgtggagacc      720

tgcccgcccc cgtactacca cttccaggac tggcgctgtg tgaacttcag cttctgccag      780

gacctgcacc acaaatgcaa gaactcgcgg aggcagggct gccaccagta cgtcattcac      840

aacaacaagt gcatccctga gtgtccctcc gggtacacga tgaattccag caacttgctg      900

tgcaccccat gcctgggtcc ctgtcccaag gtgtgccacc tcctagaagg cgagaagacc      960

atcgactcgg tgacgtctgc ccaggagctc cgaggatgca ccgtcatcaa cgggagtctg     1020

atcatcaaca ttcgaggagg caacaatctg gcagctgagc tagaagccaa cctcggcctc     1080

attgaagaaa tttcagggta tctaaaaatc cgccgatcct acgctctggt gtcactttcc     1140

ttcttccgga agttacgtct gattcgagga gagaccttgg aaattgggaa ctactccttc     1200

tatgccttgg acaaccagaa cctaaggcag ctctgggact ggagcaaaca caacctcacc     1260

atcactcagg ggaaactctt cttccactat aaccccaaac tctgcttgtc agaaatccac     1320

aagatggaag aagtttcagg aaccaagggg cgccaggaga gaaacgacat tgccctgaag     1380

accaatgggg accaggcatc ctgtgaaaat gagttactta aattttctta cattcggaca     1440

tcttttgaca agatcttgct gagatgggag ccgtactggc cccccgactt ccgagacctc     1500

ttggggttca tgctgttcta caaagaggcc ccttatcaga atgtgacgga gttcgacggg     1560

caggatgcgt gtggttccaa cagttggacg gtggtagaca ttgacccacc cctgaggtcc     1620

aacgacccca aatcacagaa ccacccaggg tggctgatgc ggggtctcaa gccctggacc     1680

cagtatgcca tctttgtgaa gaccctggtc accttttcgg atgaacgccg gacctatggg     1740

gccaagagtg acatcattta tgtccagaca gatgccacca acccctctgt gcccctggat     1800

ccaatctcag tgtctaactc atcatcccag attattctga agtggaaacc accctccgac     1860

cccaatggca acatcaccca ctacctggtt ttctgggaga ggcaggcgga agacagtgag     1920

ctgttcgagc tggattattg cctcaaaggg ctgaagctgc cctcgaggac ctggtctcca     1980

ccattcgagt ctgaagattc tcagaagcac aaccagagtg agtatgagga ttcggccggc     2040

gaatgctgct cctgtccaaa gacagactct cagatcctga aggagctgga ggagtcctcg     2100

tttaggaaga cgtttgagga ttacctgcac aacgtggttt tcgtccccag gccatct        2157


<210>  3814
<211>  1230
<212>  DNA
<213>  Homo Sapiens

<400>  3814
tgccctgagc cctgcgactg tggggaaaag tatggcttcc agatcgccga ctgtgcctac       60

cgcgacctag aatccgtgcc gcctggcttc ccggccaatg tgactacact gagcctgtca      120

gccaaccggc tgccaggctt gccggagggt gccttcaggg aggtgcccct gctgcagtcg      180

ctgtggctgg cacacaatga gatccgcacg gtggccgccg gagccctggc ctctctgagc      240

catctcaaga gcctggacct cagccacaat ctcatctctg actttgcctg gagcgacctg      300

cacaacctca gtgccctcca attgctcaag atggacagca acgagctgac cttcatcccc      360

cgcgacgcct tccgcagcct ccgtgctctg cgctcgctgc aactcaacca caaccgcttg      420

cacacattgg ccgagggcac cttcaccccg ctcaccgcgc tgtcccacct gcagatcaac      480

gagaacccct tcgactgcac ctgcggcatc gtgtggctca agacatgggc cctgaccacg      540

gccgtgtcca tcccggagca ggacaacatc gcctgcacct caccccatgt gctcaagggt      600

acaccgctga gccgcctgcc gccactgcca tgctcggcgc cctcagtgca gctcagctac      660

caacccagcc aggatggtgc cgagctgcgg cctggttttg tgctggcact gcactgtgat      720

gtggacgggc agccggcccc tcagcttcac tggcacatcc agatacccag tggcattgtg      780

gagatcacca gccccaacgt gggcactgat gggcgtgccc tgcctggcac ccctgtggcc      840

agctcccagc cgcgcttcca ggcctttgcc aatggcagcc tgcttatccc cgactttggc      900

aagctggagg aaggcaccta cagctgcctg gccaccaatg agctgggcag tgctgagagc      960

tcagtggacg tggcactggc cacgcccggt gagggtggtg aggacacact ggggcgcagg     1020

ttccatggca aagcggttga gggaaagggc tgctatacgg ttgacaacga ggtgcagcca     1080

tcagggccgg aggacaatgt ggtcatcatc tacctcagcc gtgctgggaa ccctgaggct     1140

gcagtcgcag aaggggtccc tgggcagctg cccccaggcc tgctcctgct gggccaaagc     1200

ctcctcctct tcttcttcct gacctccttc                                      1230


<210>  3815
<211>  1713
<212>  DNA
<213>  Homo Sapiens

<400>  3815
tcatgcccgg agccgtgcgc ctgcgtggac aagtacgctc accagttcgc ggactgcgct       60

tacaaagagt tgcgtgaggt gccggaagga ctgcctgcca acgtgacgac gcttagtctg      120

tccgcgaaca agatcactgt gctgcggcgc ggggccttcg ccgacgtcac acaggtcacg      180

tcgctgtggc tggcgcacaa tgaggtgcgc accgtggagc caggcgcact ggccgtgctg      240

agtcagctca agaacctcga tctgagccac aacttcatat ccagctttcc gtggagcgac      300

ctgcgcaacc tgagcgcgct gcagctgctc aaaatgaacc acaaccgcct gggctctctg      360

ccccgggacg cactcggtgc gctacccgac ctgcgttccc tgcgcatcaa caacaaccgg      420

ctgcgtacgc tggcgcctgg caccttcgac gcgcttagcg cgctgtcaca cttgcaactc      480

tatcacaatc ccttccactg cggctgcggc cttgtgtggc tgcaggcctg ggccgcgagc      540

acccgggtgt ccttacccga gcccgactcc attgcttgtg cctcgcctcc cgcgctgcag      600

ggggtgccgg tgtaccgcct gcccgccctg ccctgtgcac cgcccagcgt gcatctgagt      660

gccgagccac cgcttgaagc acccggcacc ccactgcgcg caggactggc gttcgtgtta      720

cactgcatcg ccgacggcca ccctacgcct cgcctgcaat ggcaacttca gatccccggt      780

ggcaccgtag tcttagagcc accggttctg agcggggagg acgacggggt tggggcggag      840

gaaggagagg gagaaggaga tggggatttg ctgacgcaga cccaagccca aacgccgact      900

ccagcacccg cttggccggc gcccccagcc acaccgcgct tcctggccct cgcaaatggc      960

tccctgttgg tgcccctcct gagtgccaag gaggcgggcg tctacacttg ccgtgcacac     1020

aatgagctgg gcgccaactc tacgtcaata cgcgtggcgg tggcagcaac cgggccccca     1080

aaacacgcgc ctggcgccgg gggagaaccc gacggacagg ccccgacctc tgagcgcaag     1140

tccacagcca agggccgggg caacagcgtc ctgccttcca aacccgaggg caaaatcaaa     1200

ggccaaggcc tggccaaggt cagcattctc ggggagaccg agacggagcc ggaggaggac     1260

acaagtgagg gagaggaggc cgaagaccag atcctcgcgg acccggcgga ggagcagcgc     1320

tgtggcaacg gggacccctc tcggtacgtt tctaaccacg cgttcaacca gagcgcagag     1380

ctcaagccgc acgtcttcga gctgggcgtc atcgcgctgg atgtggcgga gcgcgaggcg     1440

cgggtgcagc tgactccgct ggctgcgcgc tggggccctg ggcccggcgg ggctggcgga     1500

gccccgcgac ccgggcggcg acccctgcgc ctactctatc tgtgtccagc ggggggcggc     1560

gcggcagtgc agtggtcccg cgtagaggaa ggcgtcaacg cctactggtt ccgcggcctg     1620

cggccgggta ccaactactc cgtgtgcctg gcgctggcgg gcgaagcctg ccacgtgcaa     1680

gtggtgtttt ccaccaagaa ggagctccca tcg                                  1713


<210>  3816
<211>  3339
<212>  DNA
<213>  Homo Sapiens

<400>  3816
ttcaatgttg atgtgaaaaa ttcaatgact ttcagcggcc cggtggaaga catgtttgga       60

tatactgttc aacaatatga aaatgaagaa ggaaaatggg tgcttattgg ttctccgtta      120

gttggccaac ccaaaaacag aactggagat gtctataagt gtccagttgg gagaggtgaa      180

tcattacctt gcgtaaagtt ggatctacca gttaatacat caattcccaa tgtcacagaa      240

gtaaaggaga acatgacatt tggatcaact ttagtcacca acccaaatgg aggatttctg      300

gcttgtgggc ccttatatgc ctatagatgt ggacatttgc attacacaac tggaatctgt      360

tctgacgtca gccccacatt tcaagtcgtg aattccattg cccctgtaca agaatgcagc      420

actcaactgg acatagtcat agtgctggat ggttccaaca gtatttaccc atgggacagt      480

gttacagctt ttttaaatga ccttcttgaa agaatggata ttggtcctaa acagacacag      540

gttggaattg tacagtatgg agaaaacgtg acccatgagt tcaacctcaa taagtattct      600

tccaccgaag aggtacttgt tgcagcaaag aaaatagtcc agagaggtgg ccgccagact      660

atgacagctc ttggaataga cacagcaaga aaggaggcat tcacggaagc ccggggtgcc      720

cgaagaggag ttaaaaaagt catggttatt gtgacagatg gagagtctca tgacaatcat      780

cgactgaaga aggtcatcca agactgtgaa gatgaaaaca ttcaacggtt ttccatagct      840

attcttggca gctataaccg aggaaattta agcactgaaa aatttgtgga ggaaataaaa      900

tcaattgcaa gtgaacccac tgaaaagcat ttcttcaatg tctctgatga attggctcta      960

gtcaccattg ttaaaactct gggagaaaga atatttgccc tggaagccac agctgaccag     1020

tcagcagctt catttgaaat ggaaatgtct cagactggct tcagtgctca ttattcacag     1080

gactgggtca tgcttggagc agtaggagcc tatgattgga atggaacagt tgtcatgcag     1140

aaggctagtc aaatcataat ccctcgaaac acaaccttta atgttgagtc taccaaaaag     1200

aatgaaccgc ttgcttctta tttaggttac actgtaaact ctgctactgc ttcttctgga     1260

gatgtgctct atattgctgg acagcctcgg tacaatcata caggccaggt cattatctac     1320

aggatggaag atggaaacat caaaattctc cagacgctca gtggagaaca gattggttcc     1380

tactttggca gtattttaac aacaactgac attgacaagg attctaatac tgacattctt     1440

ctagtcggag cccctatgta catgggaaca gagaaggagg agcaaggaaa agtgtatgtg     1500

tatgctctca atcagacaag gtttgaatat caaatgagcc tggaacctat taagcagacg     1560

tgctgttcat ctcggcagca caattcatgc acaacagaaa acaaaaatga gccatgcggg     1620

gctcgttttg gaactgcaat tgctgctgta aaagacctca atcttgatgg atttaatgac     1680

atcgtgatag gagctccgct ggaagatgat cacgggggag ctgtgtacat ttatcatgga     1740

agtggcaaga ctataaggaa agagtatgca caacgtattc catcaggtgg ggatggtaag     1800

acactgaaat tttttggcca gtctatccac ggagaaatgg atttaaatgg tgacggtctg     1860

acagatgtga ctattggggg ccttggtggt gctgccctct tctggtcccg agatgtggcc     1920

gtagttaaag tgaccatgaa ttttgagcca aataaagtga atattcaaaa gaaaaactgc     1980

catatggagg gaaaggaaac agtatgcata aatgctacag tgtgttttga tgtgaaatta     2040

aagtctaaag aagacacgat ttatgaagct gatttgcagt accgtgtcac cctagattca     2100

ctaagacaaa tatcacgaag ttttttctct ggaactcaag agagaaaggt tcaaaggaac     2160

atcacagttc gaaaatcaga atgcactaag cactccttct acatgttgga caagcatgac     2220

tttcaggact ctgtgagaat aacgttggac tttaatctta ccgatccaga aaatgggcct     2280

gttcttgatg attctctacc aaactcagta catgaatata ttccctttgc caaagattgt     2340

ggaaataagg aaaaatgtat ctcagacctc agcctgcatg tcgccaccac tgaaaaggac     2400

ctgctgattg tccgatccca gaatgataag ttcaacgtta gcctcacagt caaaaataca     2460

aaggacagtg cctataacac caggacaata gtgcattatt ctccaaatct agttttttca     2520

ggaattgagg ctatccaaaa agacagttgt gaatctaatc ataatatcac atgtaaagtt     2580

ggatatccct tcctgagaag aggagagatg gtaactttca aaatattgtt tcagtttaac     2640

acatcctatc tcatggaaaa tgtgaccatt tatttaagtg caacaagtga cagcgaagaa     2700

cctcctgaaa ccctttctga taatgtagta aacatttcta tcccggtaaa atatgaagtt     2760

ggactacagt tttacagctc tgcaagtgaa taccacattt caattgctgc caatgagaca     2820

gtccctgaag ttattaattc tactgaggac attggaaatg aaattaatat cttctacttg     2880

attagaaaaa gtggatcttt tccaatgcca gagcttaagc tgtcaatttc attccccaat     2940

atgacatcaa atggttaccc tgtgctgtac ccaactggat tgtcatcttc tgagaatgca     3000

aactgcagac cccatatctt tgaggatcct ttcagtatca actctggaaa gaaaatgact     3060

acatcaactg accatctcaa acgaggcaca attctggact gcaatacatg taaatttgct     3120

accatcacat gtaatctcac ttcttctgac atcagccaag tcaatgtttc gcttatcttg     3180

tggaaaccaa cttttataaa atcatatttt tccagcttaa atcttactat aaggggagaa     3240

cttcggagtg aaaatgcatc tctggtttta agtagcagca atcaaaaaag agagcttgct     3300

attcaaatat ccaaagatgg gctaccgggc agagtgcca                            3339


<210>  3817
<211>  3309
<212>  DNA
<213>  Homo Sapiens

<400>  3817
tacaatgttg gtctcccaga agcaaaaata ttttccggtc cttcaagtga acagtttggc       60

tatgcagtgc agcagtttat aaatccaaaa ggcaactggt tactggttgg ttcaccctgg      120

agtggctttc ctgagaaccg aatgggagat gtgtataaat gtcctgttga cctatccact      180

gccacatgtg aaaaactaaa tttgcaaact tcaacaagca ttccaaatgt tactgagatg      240

aaaaccaaca tgagcctcgg cttgatcctc accaggaaca tgggaactgg aggttttctc      300

acatgtggtc ctctgtgggc acagcaatgt gggaatcagt attacacaac gggtgtgtgt      360

tctgacatca gtcctgattt tcagctctca gccagcttct cacctgcaac tcagccctgc      420

ccttccctca tagatgttgt ggttgtgtgt gatgaatcaa atagtattta tccttgggat      480

gcagtaaaga attttttgga aaaatttgta caaggcctgg atataggccc cacaaagaca      540

caggtggggt taattcagta tgccaataat ccaagagttg tgtttaactt gaacacatat      600

aaaaccaaag aagaaatgat tgtagcaaca tcccagacat cccaatatgg tggggacctc      660

acaaacacat tcggagcaat tcaatatgca agaaaatatg cttattcagc agcttctggt      720

gggcgacgaa gtgctacgaa agtaatggta gttgtaactg acggtgaatc acatgatggt      780

tcaatgttga aagctgtgat tgatcaatgc aaccatgaca atatactgag gtttggcata      840

gcagttcttg ggtacttaaa cagaaacgcc cttgatacta aaaatttaat aaaagaaata      900

aaagcaatcg ctagtattcc aacagaaaga tactttttca atgtgtctga tgaagcagct      960

ctactagaaa aggctgggac attaggagaa caaattttca gcattgaagg tactgttcaa     1020

ggaggagaca actttcagat ggaaatgtca caagtgggat tcagtgcaga ttactcttct     1080

caaaatgata ttctgatgct gggtgcagtg ggagcttttg gctggagtgg gaccattgtc     1140

cagaagacat ctcatggcca tttgatcttt cctaaacaag cctttgacca aattctgcag     1200

gacagaaatc acagttcata tttaggttac tctgtggctg caatttctac tggagaaagc     1260

actcactttg ttgctggtgc tcctcgggca aattataccg gccagatagt gctatatagt     1320

gtgaatgaga atggcaatat cacggttatt caggctcacc gaggtgacca gattggctcc     1380

tattttggta gtgtgctgtg ttcagttgat gtggataaag acaccattac agacgtgctc     1440

ttggtaggtg caccaatgta catgagtgac ctaaagaaag aggaaggaag agtctacctg     1500

tttactatca aagagggcat tttgggtcag caccaatttc ttgaaggccc cgagggcatt     1560

gaaaacactc gatttggttc agcaattgca gctctttcag acatcaacat ggatggcttt     1620

aatgatgtga ttgttggttc accactagaa aatcagaatt ctggagctgt atacatttac     1680

aatggtcatc agggcactat ccgcacaaag tattcccaga aaatcttggg atccgatgga     1740

gcctttagga gccatctcca gtactttggg aggtccttgg atggctatgg agatttaaat     1800

ggggattcca tcaccgatgt gtctattggt gcctttggac aagtggttca actctggtca     1860

caaagtattg ctgatgtagc tatagaagct tcattcacac cagaaaaaat cactttggtc     1920

aacaagaatg ctcagataat tctcaaactc tgcttcagtg caaagttcag acctactaag     1980

caaaacaatc aagtggccat tgtatataac atcacacttg atgcagatgg attttcatcc     2040

agagtaacct ccagggggtt atttaaagaa aacaatgaaa ggtgcctgca gaagaatatg     2100

gtagtaaatc aagcacagag ttgccccgag cacatcattt atatacagga gccctctgat     2160

gttgtcaact ctttggattt gcgtgtggac atcagtctgg aaaaccctgg cactagccct     2220

gcccttgaag cctattctga gactgccaag gtcttcagta ttcctttcca caaagactgt     2280

ggtgaggacg gactttgcat ttctgatcta gtcctagatg tccgacaaat accagctgct     2340

caagaacaac cctttattgt cagcaaccaa aacaaaaggt taacattttc agtaacgctg     2400

aaaaataaaa gggaaagtgc atacaacact ggaattgttg ttgatttttc agaaaacttg     2460

ttttttgcat cattctccct gccggttgat gggacagaag taacatgcca ggtggctgca     2520

tctcagaagt ctgttgcctg cgatgtaggc taccctgctt taaagagaga acaacaggtg     2580

acttttacta ttaactttga cttcaatctt caaaaccttc agaatcaggc gtctctcagt     2640

ttccaagcct taagtgaaag ccaagaagaa aacaaggctg ataatttggt caacctcaaa     2700

attcctctcc tgtatgatgc tgaaattcac ttaacaagat ctaccaacat aaatttttat     2760

gaaatctctt cggatgggaa tgttccttca atcgtgcaca gttttgaaga tgttggtcca     2820

aaattcatct tctccctgaa ggtaacaaca ggaagtgttc cagtaagcat ggcaactgta     2880

atcatccaca tccctcagta taccaaagaa aagaacccac tgatgtacct aactggggtg     2940

caaacagaca aggctggtga catcagttgt aatgcagata tcaatccact gaaaatagga     3000

caaacatctt cttctgtatc tttcaaaagt gaaaatttca ggcacaccaa agaattgaac     3060

tgcagaactg cttcctgtag taatgttacc tgctggttga aagacgttca catgaaagga     3120

gaatactttg ttaatgtgac taccagaatt tggaacggga ctttcgcatc atcaacgttc     3180

cagacagtac agctaacggc agctgcagaa atcaacacct ataaccctga gatatatgtg     3240

attgaagata acactgttac gattcccctg atgataatga aacctgatga gaaagccgaa     3300

gtaccaaca                                                             3309


<210>  3818
<211>  2886
<212>  DNA
<213>  Homo Sapiens

<400>  3818
ttgaacctgg acccagtgca gctcaccttc tatgcaggcc ccaatggcag ccagtttgga       60

ttttcactgg acttccacaa ggacagccat gggagagtgg ccatcgtggt gggcgccccg      120

cggaccctgg gccccagcca ggaggagacg ggcggcgtgt tcctgtgccc ctggagggcc      180

gagggcggcc agtgcccctc gctgctcttt gacctccgtg atgagacccg aaatgtaggc      240

tcccaaactt tacaaacctt caaggcccgc caaggactgg gggcgtcggt cgtcagctgg      300

agcgacgtca ttgtggcctg cgccccctgg cagcactgga acgtcctaga aaagactgag      360

gaggctgaga agacgcccgt aggtagctgc tttttggctc agccagagag cggccgccgc      420

gccgagtact ccccctgtcg cgggaacacc ctgagccgca tttacgtgga aaatgatttt      480

agctgggaca agcgttactg tgaagcgggc ttcagctccg tggtcactca ggccggagag      540

ctggtgcttg gggctcctgg cggctattat ttcttaggtc tcctggccca ggctccagtt      600

gcggatattt tctcgagtta ccgcccaggc atccttttgt ggcacgtgtc ctcccagagc      660

ctctcctttg actccagcaa cccagagtac ttcgacggct actgggggta ctcggtggcc      720

gtgggcgagt tcgacgggga tctcaacact acagaatatg tcgtcggtgc ccccacttgg      780

agctggaccc tgggagcggt ggaaattttg gattcctact accagaggct gcatcggctg      840

cgcggagagc agatggcgtc gtattttggg cattcagtgg ctgtcactga cgtcaacggg      900

gatgggaggc atgatctgct ggtgggcgct ccactgtata tggagagccg ggcagaccga      960

aaactggccg aagtggggcg tgtgtatttg ttcctgcagc cgcgaggccc ccacgcgctg     1020

ggtgccccca gcctcctgct gactggcaca cagctctatg ggcgattcgg ctctgccatc     1080

gcacccctgg gcgacctcga ccgggatggc tacaatgaca ttgcagtggc tgccccctac     1140

gggggtccca gtggccgggg ccaagtgctg gtgttcctgg gtcagagtga ggggctgagg     1200

tcacgtccct cccaggtcct ggacagcccc ttccccacag gctctgcctt tggcttctcc     1260

cttcgaggtg ccgtagacat cgatgacaac ggatacccag acctgatcgt gggagcttac     1320

ggggccaacc aggtggctgt gtacagagct cagccagtgg tgaaggcctc tgtccagcta     1380

ctggtgcaag attcactgaa tcctgctgtg aagagctgtg tcctacctca gaccaagaca     1440

cccgtgagct gcttcaacat ccagatgtgt gttggagcca ctgggcacaa cattcctcag     1500

aagctatccc taaatgccga gctgcagctg gaccggcaga agccccgcca gggccggcgg     1560

gtgctgctgc tgggctctca acaggcaggc accaccctga acctggatct gggcggaaag     1620

cacagcccca tctgccacac caccatggcc ttccttcgag atgaggcaga cttccgggac     1680

aagctgagcc ccattgtgct cagcctcaat gtgtccctac cgcccacgga ggctggaatg     1740

gcccctgctg tcgtgctgca tggagacacc catgtgcagg agcagacacg aatcgtcctg     1800

gactgtgggg aagatgacgt atgtgtgccc cagcttcagc tcactgccag cgtgacgggc     1860

tccccgctcc tagttggggc agataatgtc ctggagctgc agatggacgc agccaacgag     1920

ggcgaggggg cctatgaagc agagctggcc gtgcacctgc cccagggcgc ccactacatg     1980

cgggccctaa gcaatgtcga gggctttgag agactcatct gtaatcagaa gaaggagaat     2040

gagaccaggg tggtgctgtg tgagctgggc aaccccatga agaagaacgc ccagatagga     2100

atcgcgatgt tggtgagcgt ggggaatctg gaagaggctg gggagtctgt gtccttccag     2160

ctgcagatac ggagcaagaa cagccagaat ccaaacagca agattgtgct gctggacgtg     2220

ccggtccggg cagaggccca agtggagctg cgagggaact cctttccagc ctccctggtg     2280

gtggcagcag aagaaggtga gagggagcag aacagcttgg acagctgggg acccaaagtg     2340

gagcacacct atgagctcca caacaatggc cctgggactg tgaatggtct tcacctcagc     2400

atccaccttc cgggacagtc ccagccctcc gacctgctct acatcctgga tatacagccc     2460

caggggggcc ttcagtgctt cccacagcct cctgtcaacc ctctcaaggt ggactggggg     2520

ctgcccatcc ccagcccctc ccccattcac ccggcccatc acaagcggga tcgcagacag     2580

atcttcctgc cagagcccga gcagccctcg aggcttcagg atccagttct cgtaagctgc     2640

gactcggcgc cctgtactgt ggtgcagtgt gacctgcagg agatggcgcg cgggcagcgg     2700

gccatggtca cggtgctggc cttcctgtgg ctgcccagcc tctaccagag gcctctggat     2760

cagtttgtgc tgcagtcgca cgcatggttc aacgtgtcct ccctccccta tgcggtgccc     2820

ccgctcagcc tgccccgagg ggaagctcag gtgtggacac agctgctccg ggccttggag     2880

gagagg                                                                2886


<210>  3819
<211>  2877
<212>  DNA
<213>  Homo Sapiens

<400>  3819
ttcaacctgg atacccgatt cctggtagtg aaggaggccg ggaacccggg cagcctcttc       60

ggctactcgg tcgccctcca tcggcagaca gagcggcagc agcgctacct gctcctggct      120

ggtgcccccc gggagctcgc tgtgcccgat ggctacacca accggactgg tgctgtgtac      180

ctgtgcccac tcactgccca caaggatgac tgtgagcgga tgaacatcac agtgaaaaat      240

gaccctggcc atcacattat tgaggacatg tggcttggag tgactgtggc cagccagggc      300

cctgcaggca gagttctggt ctgtgcccac cgctacaccc aggtgctgtg gtcagggtca      360

gaagaccagc ggcgcatggt gggcaagtgc tacgtgcgag gcaatgacct agagctggac      420

tccagtgatg actggcagac ctaccacaac gagatgtgca atagcaacac agactacctg      480

gagacgggca tgtgccagct gggcaccagc ggtggcttca cccagaacac tgtgtacttc      540

ggcgcccccg gtgcctacaa ctggaaagga aacagctaca tgattcagcg caaggagtgg      600

gacttatctg agtatagtta caaggaccca gaggaccaag gaaacctcta tattgggtac      660

acgatgcagg taggcagctt catcctgcac cccaaaaaca tcaccattgt gacaggtgcc      720

ccacggcacc gacatatggg cgcggtgttc ttgctgagcc aggaggcagg cggagacctg      780

cggaggaggc aggtgctgga gggctcgcag gtgggcgcct attttggcag cgccattgcc      840

ctggcagacc tgaacaatga tgggtggcag gacctcctgg tgggcgcccc ctactacttc      900

gagaggaaag aggaagtagg gggtgccatc tatgtcttca tgaaccaggc gggaacctcc      960

ttccctgctc acccctcact ccttcttcat ggccccagtg gctctgcctt tggtttatct     1020

gtggccagca ttggtgacat caaccaggat ggatttcagg atattgctgt gggagctccg     1080

tttgaaggct tgggcaaagt gtacatctat cacagtagct ctaaggggct ccttagacag     1140

ccccagcagg taatccatgg agagaagctg ggactgcctg ggttggccac cttcggctat     1200

tccctcagtg ggcagatgga tgtggatgag aacttctacc cagaccttct agtgggaagc     1260

ctgtcagacc acattgtgct gctgcgggcc cggcccgtca tcaacatcgt ccacaagacc     1320

ttggtgccca ggccagctgt gctggaccct gcactttgca cggccacctc ttgtgtgcaa     1380

gtggagctgt gctttgctta caaccagagt gccgggaacc ccaactacag gcgaaacatc     1440

accctggcct acactctgga ggctgacagg gaccgccggc cgccccggtt ccgctttgcc     1500

ggcagtgagt ccgctgtctt ccacggcttc ttctccatgc ccgagatgcg ctgccagaag     1560

ctggagctgc tcctgatgga caacctccgt gacaaactcc gccccatcat catctccatg     1620

aactactctt tacctttgcg gatgcccgat cgcccccggc tggggctgcg gtccctggac     1680

gcctacccga tcctcaacca ggcacaggct ctggagaacc acactgaggt ccagttccag     1740

aaggagtgcg ggcctgacaa caagtgtgag agcaacttgc agatgcgggc agccttcgtg     1800

tcagagcagc agcagaagct gagcaggctc cagtacagca gagacgtccg gaaattgctc     1860

ctgagcatca acgtgacgaa cacccggacc tcggagcgct ccggggagga cgcccacgag     1920

gcgctgctca ccctggtggt gcctcccgcc ctgctgctgt cctcagtgcg cccccccggg     1980

gcctgccaag ctaatgagac catcttttgc gagctgggga accccttcaa acggaaccag     2040

aggatggagc tgctcatcgc ctttgaggtc atcggggtga ccctgcacac aagggacctt     2100

caggtgcagc tgcagctctc cacgtcgagt caccaggaca acctgtggcc catgatcctc     2160

actctgctgg tggactatac actccagacc tcgcttagca tggtaaatca ccggctacaa     2220

agcttctttg gggggacagt gatgggtgag tctggcatga aaactgtgga ggatgtagga     2280

agccccctca agtatgaatt ccaggtgggc ccaatggggg aggggctggt gggcctgggg     2340

accctggtcc taggtctgga gtggccctac gaagtcagca atggcaagtg gctgctgtat     2400

cccacggaga tcaccgtcca tggcaatggg tcctggccct gccgaccacc tggagacctt     2460

atcaaccctc tcaacctcac tctttctgac cctggggaca ggccatcatc cccacagcgc     2520

aggcggcgac agctggatcc agggggaggc cagggccccc cacctgtcac tctggctgct     2580

gccaaaaaag ccaagtctga gactgtgctg acctgtgcca cagggcgtgc ccactgtgtg     2640

tggctagagt gccccatccc tgatgccccc gttgtcacca acgtgactgt gaaggcacga     2700

gtgtggaaca gcaccttcat cgaggattac agagactttg accgagtccg ggtaaatggc     2760

tgggctaccc tattcctccg aaccagcatc cccaccatca acatggagaa caagaccacg     2820

tggttctctg tggacattga ctcggagctg gtggaggagc tgccggccga aatcgag        2877


<210>  3820
<211>  2829
<212>  DNA
<213>  Homo Sapiens

<400>  3820
aacgtggaca ctgagagcgc gctgctttac cagggccccc acaacacgct gttcggctac       60

tcggtcgtgc tgcacagcca cggggcgaac cgatggctcc tagtgggtgc gcccactgcc      120

aactggctcg ccaacgcttc agtgatcaat cccggggcga tttacagatg caggatcgga      180

aagaatcccg gccagacgtg cgaacagctc cagctgggta gccctaatgg agaaccttgt      240

ggaaagactt gtttggaaga gagagacaat cagtggttgg gggtcacact ttccagacag      300

ccaggagaaa atggatccat cgtgacttgt gggcatagat ggaaaaatat attttacata      360

aagaatgaaa ataagctccc cactggtggt tgctatggag tgccccctga tttacgaaca      420

gaactgagta aaagaatagc tccgtgttat caagattatg tgaaaaaatt tggagaaaat      480

tttgcatcat gtcaagctgg aatatccagt ttttacacaa aggatttaat tgtgatgggg      540

gccccaggat catcttactg gactggctct ctttttgtct acaatataac tacaaataaa      600

tacaaggctt ttttagacaa acaaaatcaa gtaaaatttg gaagttattt aggatattca      660

gtcggagctg gtcattttcg gagccagcat actaccgaag tagtcggagg agctcctcaa      720

catgagcaga ttggtaaggc atatatattc agcattgatg aaaaagaact aaatatctta      780

catgaaatga aaggtaaaaa gcttggatcg tactttggag cttctgtctg tgctgtggac      840

ctcaatgcag atggcttctc agatctgctc gtgggagcac ccatgcagag caccatcaga      900

gaggaaggaa gagtgtttgt gtacatcaac tctggctcgg gagcagtaat gaatgcaatg      960

gaaacaaacc tcgttggaag tgacaaatat gctgcaagat ttggggaatc tatagttaat     1020

cttggcgaca ttgacaatga tggctttgaa gatgttgcta tcggagctcc acaagaagat     1080

gacttgcaag gtgctattta tatttacaat ggccgtgcag atgggatctc gtcaaccttc     1140

tcacagagaa ttgaaggact tcagatcagc aaatcgttaa gtatgtttgg acagtctata     1200

tcaggacaaa ttgatgcaga taataatggc tatgtagatg tagcagttgg tgcttttcgg     1260

tctgattctg ctgtcttgct aaggacaaga cctgtagtaa ttgttgacgc ttctttaagc     1320

caccctgagt cagtaaatag aacgaaattt gactgtgttg aaaatggatg gccttctgtg     1380

tgcatagatc taacactttg tttctcatat aagggcaagg aagttccagg ttacattgtt     1440

ttgttttata acatgagttt ggatgtgaac agaaaggcag agtctccacc aagattctat     1500

ttctcttcta atggaacttc tgacgtgatt acaggaagca tacaggtgtc cagcagagaa     1560

gctaactgta gaacacatca agcatttatg cggaaagatg tgcgggacat cctcacccca     1620

attcagattg aagctgctta ccaccttggt cctcatgtca tcagtaaacg aagtacagag     1680

gaattcccac cacttcagcc aattcttcag cagaagaaag aaaaagacat aatgaaaaaa     1740

acaataaact ttgcaaggtt ttgtgcccat gaaaattgtt ctgctgattt acaggtttct     1800

gcaaagattg ggtttttgaa gccccatgaa aataaaacat atcttgctgt tgggagtatg     1860

aagacattga tgttgaatgt gtccttgttt aatgctggag atgatgcata tgaaacgact     1920

ctacatgtca aactacccgt gggtctttat ttcattaaga ttttagagct ggaagagaag     1980

caaataaact gtgaagtcac agataactct ggcgtggtac aacttgactg cagtattggc     2040

tatatatatg tagatcatct ctcaaggata gatattagct ttctcctgga tgtgagctca     2100

ctcagcagag cggaagagga cctcagtatc acagtgcatg ctacctgtga aaatgaagag     2160

gaaatggaca atctaaagca cagcagagtg actgtagcaa tacctttaaa atatgaggtt     2220

aagctgactg ttcatgggtt tgtaaaccca acttcatttg tgtatggatc aaatgatgaa     2280

aatgagcctg aaacgtgcat ggtggagaaa atgaacttaa ctttccatgt tatcaacact     2340

ggcaatagta tggctcccaa tgttagtgtg gaaataatgg taccaaattc ttttagcccc     2400

caaactgata agctgttcaa cattttggat gtccagacta ctactggaga atgccacttt     2460

gaaaattatc aaagagtgtg tgcattagag cagcaaaaga gtgcaatgca gaccttgaaa     2520

ggcatagtcc ggttcttgtc caagactgat aagaggctat tgtactgcat aaaagctgat     2580

ccacattgtt taaatttctt gtgtaatttt gggaaaatgg aaagtggaaa agaagccagt     2640

gttcatatcc aactggaagg ccggccatcc attttagaaa tggatgagac ttcagcactc     2700

aagtttgaaa taagagcaac aggttttcca gagccaaatc caagagtaat tgaactaaac     2760

aaggatgaga atgttgcgca tgttctactg gaaggactac atcatcaaag acccaaacgt     2820

tatttcacc                                                             2829


<210>  3821
<211>  2862
<212>  DNA
<213>  Homo Sapiens

<400>  3821
ttcaacttag acgcggaggc cccagcagta ctctcggggc ccccgggctc cttcttcgga       60

ttctcagtgg agttttaccg gccgggaaca gacggggtca gtgtgctggt gggagcaccc      120

aaggctaata ccagccagcc aggagtgctg cagggtggtg ctgtctacct ctgtccttgg      180

ggtgccagcc ccacacagtg cacccccatt gaatttgaca gcaaaggctc tcggctcctg      240

gagtcctcac tgtccagctc agagggagag gagcctgtgg agtacaagtc cttgcagtgg      300

ttcggggcaa cagttcgagc ccatggctcc tccatcttgg catgcgctcc actgtacagc      360

tggcgcacag agaaggagcc actgagcgac cccgtgggca cctgctacct ctccacagat      420

aacttcaccc gaattctgga gtatgcaccc tgccgctcag atttcagctg ggcagcagga      480

cagggttact gccaaggagg cttcagtgcc gagttcacca agactggccg tgtggtttta      540

ggtggaccag gaagctattt ctggcaaggc cagatcctgt ctgccactca ggagcagatt      600

gcagaatctt attaccccga gtacctgatc aacctggttc aggggcagct gcagactcgc      660

caggccagtt ccatctatga tgacagctac ctaggatact ctgtggctgt tggtgaattc      720

agtggtgatg acacagaaga ctttgttgct ggtgtgccca aagggaacct cacttacggc      780

tatgtcacca tccttaatgg ctcagacatt cgatccctct acaacttctc aggggaacag      840

atggcctcct actttggcta tgcagtggcc gccacagacg tcaatgggga cgggctggat      900

gacttgctgg tgggggcacc cctgctcatg gatcggaccc ctgacgggcg gcctcaggag      960

gtgggcaggg tctacgtcta cctgcagcac ccagccggca tagagcccac gcccaccctt     1020

accctcactg gccatgatga gtttggccga tttggcagct ccttgacccc cctgggggac     1080

ctggaccagg atggctacaa tgatgtggcc atcggggctc cctttggtgg ggagacccag     1140

cagggagtag tgtttgtatt tcctgggggc ccaggagggc tgggctctaa gccttcccag     1200

gttctgcagc ccctgtgggc agccagccac accccagact tctttggctc tgcccttcga     1260

ggaggccgag acctggatgg caatggatat cctgatctga ttgtggggtc ctttggtgtg     1320

gacaaggctg tggtatacag gggccgcccc atcgtgtccg ctagtgcctc cctcaccatc     1380

ttccccgcca tgttcaaccc agaggagcgg agctgcagct tagaggggaa ccctgtggcc     1440

tgcatcaacc ttagcttctg cctcaatgct tctggaaaac acgttgctga ctccattggt     1500

ttcacagtgg aacttcagct ggactggcag aagcagaagg gaggggtacg gcgggcactg     1560

ttcctggcct ccaggcaggc aaccctgacc cagaccctgc tcatccagaa tggggctcga     1620

gaggattgca gagagatgaa gatctacctc aggaacgagt cagaatttcg agacaaactc     1680

tcgccgattc acatcgctct caacttctcc ttggaccccc aagccccagt ggacagccac     1740

ggcctcaggc cagccctaca ttatcagagc aagagccgga tagaggacaa ggctcagatc     1800

ttgctggact gtggagaaga caacatctgt gtgcctgacc tgcagctgga agtgtttggg     1860

gagcagaacc atgtgtacct gggtgacaag aatgccctga acctcacttt ccatgcccag     1920

aatgtgggtg agggtggcgc ctatgaggct gagcttcggg tcaccgcccc tccagaggct     1980

gagtactcag gactcgtcag acacccaggg aacttctcca gcctgagctg tgactacttt     2040

gccgtgaacc agagccgcct gctggtgtgt gacctgggca accccatgaa ggcaggagcc     2100

agtctgtggg gtggccttcg gtttacagtc cctcatctcc gggacactaa gaaaaccatc     2160

cagtttgact tccagatcct cagcaagaat ctcaacaact cgcaaagcga cgtggtttcc     2220

tttcggctct ccgtggaggc tcaggcccag gtcaccctga acggtgtctc caagcctgag     2280

gcagtgctat tcccagtaag cgactggcat ccccgagacc agcctcagaa ggaggaggac     2340

ctgggacctg ctgtccacca tgtctatgag ctcatcaacc aaggccccag ctccattagc     2400

cagggtgtgc tggaactcag ctgtccccag gctctggaag gtcagcagct cctatatgtg     2460

accagagtta cgggactcaa ctgcaccacc aatcacccca ttaacccaaa gggcctggag     2520

ttggatcccg agggttccct gcaccaccag caaaaacggg aagctccaag ccgcagctct     2580

gcttcctcgg gacctcagat cctgaaatgc ccggaggctg agtgtttcag gctgcgctgt     2640

gagctcgggc ccctgcacca acaagagagc caaagtctgc agttgcattt ccgagtctgg     2700

gccaagactt tcttgcagcg ggagcaccag ccatttagcc tgcagtgtga ggctgtgtac     2760

aaagccctga agatgcccta ccgaatcctg cctcggcagc tgccccaaaa agagcgtcag     2820

gtggccacag ctgtgcaatg gaccaaggca gaaggcagct at                        2862


<210>  3822
<211>  2964
<212>  DNA
<213>  Homo Sapiens

<400>  3822
ttcaacttgg acactcggga ggacaacgtg atccggaaat atggagaccc cgggagcctc       60

ttcggcttct cgctggccat gcactggcaa ctgcagcccg aggacaagcg gctgttgctc      120

gtgggggccc cgcgggcaga agcgcttcca ctgcagagag ccaacagaac gggagggctg      180

tacagctgcg acatcaccgc ccgggggcca tgcacgcgga tcgagtttga taacgatgct      240

gaccccacgt cagaaagcaa ggaagatcag tggatggggg tcaccgtcca gagccaaggt      300

ccagggggca aggtcgtgac atgtgctcac cgatatgaaa aaaggcagca tgttaatacg      360

aagcaggaat cccgagacat ctttgggcgg tgttatgtcc tgagtcagaa tctcaggatt      420

gaagacgata tggatggggg agattggagc ttttgtgatg ggcgattgag aggccatgag      480

aaatttggct cttgccagca aggtgtagca gctactttta ctaaagactt tcattacatt      540

gtatttggag ccccgggtac ttataactgg aaagggattg ttcgtgtaga gcaaaagaat      600

aacacttttt ttgacatgaa catctttgaa gatgggcctt atgaagttgg tggagagact      660

gagcatgatg aaagtctcgt tcctgttcct gctaacagtt acttaggttt ttctttggac      720

tcagggaaag gtattgtttc taaagatgag atcacttttg tatctggtgc tcccagagcc      780

aatcacagtg gagccgtggt tttgctgaag agagacatga agtctgcaca tctcctccct      840

gagcacatat tcgatggaga aggtctggcc tcttcatttg gctatgatgt ggcggtggtg      900

gacctcaaca aggatgggtg gcaagatata gttattggag ccccacagta ttttgataga      960

gatggagaag ttggaggtgc agtgtatgtc tacatgaacc agcaaggcag atggaataat     1020

gtgaagccaa ttcgtcttaa tggaaccaaa gattctatgt ttggcattac agtaaaaaat     1080

attggagata ttaatcaaga tggctaccca gatattgcag ttggagctcc gtatgatgac     1140

ttgggaaagg tttttatcta tcatggatct gcaaatggaa taaataccaa accaacacag     1200

gttctcaagg gtatatcacc ttattttgga tattcaattg ctggaaacat ggaccttgat     1260

cgaaattcct accctgatgt tgctgttggt tccctctcag attcagtaac tattttcaga     1320

tcccggcctg tgattaatat tcagaaaacc atcacagtaa ctcctaacag aattgacctc     1380

cgccagaaaa cagcgtgtgg ggcgcctagt gggatatgcc tccaggttaa atcctgtttt     1440

gaatatactg ctaaccccgc tggttataat ccttcaatat caattgtggg cacacttgaa     1500

gctgaaaaag aaagaagaaa atctgggcta tcctcaagag ttcagtttcg aaaccaaggt     1560

tctgagccca aatatactca agaactaact ctgaagaggc agaaacagaa agtgtgcatg     1620

gaggaaaccc tgtggctaca ggataatatc agagataaac tgcgtcccat tcccataact     1680

gcctcagtgg agatccaaga gccaagctct cgtaggcgag tgaattcact tccagaagtt     1740

cttccaattc tgaattcaga tgaacccaag acagctcata ttgatgttca cttcttaaaa     1800

gagggatgtg gagacgacaa tgtatgtaac agcaacctta aactagaata taaattttgc     1860

acccgagaag gaaatcaaga caaattttct tatttaccaa ttcaaaaagg tgtaccagaa     1920

ctagttctaa aagatcagaa ggatattgct ttagaaataa cagtgacaaa cagcccttcc     1980

aacccaagga atcccacaaa agatggcgat gatgcccatg aggctaaact gattgcaacg     2040

tttccagaca ctttaaccta ttctgcatat agagaactga gggctttccc tgagaaacag     2100

ttgagttgtg ttgccaacca gaatggctcg caagctgact gtgagctcgg aaatcctttt     2160

aaaagaaatt caaatgtcac tttttatttg gttttaagta caactgaagt cacctttgac     2220

accccagatc tggatattaa tctgaagtta gaaacaacaa gcaatcaaga taatttggct     2280

ccaattacag ctaaagcaaa agtggttatt gaactgcttt tatcggtctc gggagttgct     2340

aaaccttccc aggtgtattt tggaggtaca gttgttggcg agcaagctat gaaatctgaa     2400

gatgaagtgg gaagtttaat agagtatgaa ttcagggtaa taaacttagg taaacctctt     2460

acaaacctcg gcacagcaac cttgaacatt cagtggccaa aagaaattag caatgggaaa     2520

tggttgcttt atttggtgaa agtagaatcc aaaggattgg aaaaggtaac ttgtgagcca     2580

caaaaggaga taaactccct gaacctaacg gagtctcaca actcaagaaa gaaacgggaa     2640

attactgaaa aacagataga tgataacaga aaattttctt tatttgctga aagaaaatac     2700

cagactctta actgtagcgt gaacgtgaac tgtgtgaaca tcagatgccc gctgcggggg     2760

ctggacagca aggcgtctct tattttgcgc tcgaggttat ggaacagcac atttctagag     2820

gaatattcca aactgaacta cttggacatt ctcatgcgag ccttcattga tgtgactgct     2880

gctgccgaaa atatcaggct gccaaatgca ggcactcagg ttcgagtgac tgtgtttccc     2940

tcaaagactg tagctcagta ttcg                                            2964


<210>  3823
<211>  3015
<212>  DNA
<213>  Homo Sapiens

<400>  3823
ttcaatctgg acgtgatggg tgccttgcgc aaggagggcg agccaggcag cctcttcggc       60

ttctctgtgg ccctgcaccg gcagttgcag cccagacccc agagctggct gctggtgggt      120

gctccccagg ccctggctct tcctgggcag caggcgaatc gcactggagg cctcttcgct      180

tgcccattga gcctggagga gactgactgc tacagagtgg acatcgacca gggagctgat      240

atgcaaaagg aaagcaagga gaaccagtgg ttgggagtca gtgttcggag ccaggggcct      300

gggggcaaga ttgttacctg tgcacacaga tatgaggcaa ggcagcgagt ggaccagatc      360

ctggagacgc gggatatgat tggtcgctgc tttgtgctca gccaggacct ggccatccgg      420

gatgagttgg atggtgggga atggaagttc tgtgagggac gcccccaagg ccatgaacaa      480

tttgggttct gccagcaggg cacagctgcc gccttctccc ctgatagcca ctacctcctc      540

tttggggccc caggaaccta taattggaag gggttgcttt ttgtgaccaa cattgatagc      600

tcagaccccg accagctggt gtataaaact ttggaccctg ctgaccggct cccaggacca      660

gccggagact tggccctcaa tagctactta ggcttctcta ttgactcggg gaaaggtctg      720

gtgcgtgcag aagagctgag ctttgtggct ggagcccccc gcgccaacca caagggtgct      780

gtggtcatcc tgcgcaagga cagcgccagt cgcctggtgc ccgaggttat gctgtctggg      840

gagcgcctga cctccggctt tggctactca ctggctgtgg ctgacctcaa cagtgatggc      900

tggccagacc tgatagtggg tgccccctac ttctttgagc gccaagaaga gctggggggt      960

gctgtgtatg tgtacttgaa ccaggggggt cactgggctg ggatctcccc tctccggctc     1020

tgcggctccc ctgactccat gttcgggatc agcctggctg tcctggggga cctcaaccaa     1080

gatggctttc cagatattgc agtgggtgcc ccctttgatg gtgatgggaa agtcttcgtc     1140

taccatggga gcagcctggg ggttgtcgcc aaaccttcac aggtgctgga gggcgaggct     1200

gtgggcatca agagcttcgg ctactccctg tcaggcagct tggatatgga tgggaaccaa     1260

taccctgacc tgctggtggg ctccatggct gacaccgcag tgctcttcag ggccagaccc     1320

atcctccatg tctcccatga ggtctctatt gctccacgaa gcatcgacct ggagcagccc     1380

aactgtgctg gcggccactc ggtctgtgtg gacctaaggg tctgtttcag ctacattgca     1440

gtccccagca gctatagccc tactgtggcc ctggactatg tgttagatgc ggacacagac     1500

cggaggctcc ggggccaggt tccccatgtg acgttcctga gccgtaacct ggaagaaccc     1560

aagcaccagg cctcgggcac cgtgtggctg aagcaccagc atgaccgagt ctgtggagac     1620

gccatgttcc agctccagga aaatgtcaaa gacaagcttc gggccattgt agtgaccttg     1680

tcctacagtc tccagacccc tcggctccgg cgacaggctc ctggccaggg gctgcctcca     1740

gtggccccca tcctcaatgc ccaccagccc agcacccagc gggcagagat ccacttcctg     1800

aagcaaggct gtggtgaaga caagatctgc cagagcaatc tgcagctggt ccacgtccgc     1860

ttctgtaccc gggtcagcga cacggaattc caacctctgc caatggatgt ggatggaaca     1920

acagccctgt ttgcactgag tgggcagcca gtcattggcc tggagctgat ggtcaccaac     1980

ctgccatcgg acccagccca gccccaggct gatggggatg atgcccatga agcccagctc     2040

ctggtcatgc ttcctgactc actgcactac tcaggggtcc gggccctgga ccctgcggag     2100

aagccactct gcctgtccaa tgagaatgcc tcccatgttg agtgtgagct ggggaacccc     2160

atgaagagag gtgcccaggt caccttctac ctcatcctta gcacctccgg gatcagcatt     2220

gagaccacgg aactggaggt agagctgctg ttggccacga tcagtgagca ggagctgcat     2280

ccagtctctg cacgagcccg tgtcttcatt gagctgccac tgtccattgc aggaatggcc     2340

attccccagc aactcttctt ctctggtgtg gtgaggggcg agagagccat gcagtctgag     2400

cgggatgtgg gcagcaaggt caagtatgag gtcacggttt ccaaccaagg ccagtcgctc     2460

agaaccctgg gctctgcctt cctcaacatc atgtggcctc atgagattgc caatgggaag     2520

tggttgctgt acccaatgca ggttgagctg gagggcgggc aggggcctgg gcagaaaggg     2580

ctttgctctc ccaggcccaa catcctccac ctggatgtgg acagtaggga taggaggcgg     2640

cgggagctgg agccacctga gcagcaggag cctggtgagc ggcaggagcc cagcatgtcc     2700

tggtggccag tgtcctctgc tgagaagaag aaaaacatca ccctggactg cgcccggggc     2760

acggccaact gtgtggtgtt cagctgccca ctctacagct ttgaccacgc ggctgtgctg     2820

catgtctggg gccgtctctg gaacagcacc tttctggagg agtactcagc tgtgaagtcc     2880

ctggaagtga ttgtccgggc caacatcaca gtgaagtcct ccataaagaa cttgatgctc     2940

cgagatgcct ccacagtgat cccagtgatg gtatacttgg accccatggc tgtggtggca     3000

gaaggagtgc cctgg                                                      3015


<210>  3824
<211>  2922
<212>  DNA
<213>  Homo Sapiens

<400>  3824
ttcaacctgg acgtggaaaa gctcacagtg tacagcggcc ccaagggcag ctacttcggc       60

tacgccgtgg acttccacat acccgacgcc cgcacagcga gtgtcttggt gggggcgccc      120

aaagccaaca ccagccagcc cgatatcgtg gaagggggag ccgtctatta ctgtccttgg      180

cccgcggagg ggtctgcgca gtgcaggcag ataccgtttg acaccaccaa caacagaaag      240

atcagagtta atggaaccaa agaacctatc gagttcaaat ccaatcagtg gtttggagca      300

acagtgaaag ctcacaaagg aaaagttgtg gcctgtgctc ctttatatca ctggagaact      360

cttaaaccga caccagaaaa ggacccagtt ggcacctgct atgtagcaat tcagaacttc      420

agcgcctatg ccgagttctc tccttgccgg aacagcaatg ctgatccgga aggccagggt      480

tactgccaag caggatttag tctggatttt tataagaatg gagaccttat tgtgggagga      540

cctgggagtt tctactggca aggacaagtg atcactgcca gtgttgcaga tatcattgca      600

aattactcat tcaaggatat cctcaggaaa ctggcaggag aaaagcagac ggaagtggct      660

ccagcttcct atgatgacag ttaccttgga tactcagttg ctgctgggga gtttactggg      720

gattctcagc aagaattggt tgctggaatt ccaagaggag cacagaattt tggatatgtt      780

tccatcatta actctacgga tatgacgttt attcagaatt tcacgggaga acagatggca      840

tcttattttg gatataccgt tgtcgtatca gatgttaaca gtgatggact ggatgatgtc      900

ctggttgggg cacctctctt tatggaacgt gaatttgaga gcaaccccag agaagtaggg      960

caaatctacc tgtatttgca agtgagctct ctcctcttca gagaccccca gatcctcact     1020

ggcaccgaga cgtttgggag attcggtagt gctatggcac acttaggaga cctgaaccaa     1080

gatggataca atgacattgc catcggagtg ccttttgcag gcaaggatca aagaggcaaa     1140

gtgctcattt ataatgggaa caaagatggc ttaaacacca agccttccca agttctgcaa     1200

ggagtgtggg cctcacatgc tgtcccttcc ggatttggct ttactttaag aggagattca     1260

gacatagaca agaatgatta cccagatttg attgtgggtg catttggaac aggaaaagtc     1320

gctgtttaca gagcaagacc ggttgtgact gtagatgccc agcttctgct gcacccaatg     1380

attatcaatc ttgaaaataa aacttgccag gttccagact ctatgacatc tgctgcctgc     1440

ttttctttaa gagtatgtgc atctgtcaca ggccagagca ttgcaaacac aatagtcttg     1500

atggcagagg tgcaattaga ttccctgaaa cagaaaggag ctattaaacg gacgctcttc     1560

cttgataacc atcaggctca tcgcgtcttc cctcttgtga taaaaaggca gaaatcccac     1620

cagtgccagg atttcatcgt ttaccttcga gatgaaactg aattccgaga taaattatct     1680

ccaatcaaca ttagtttgaa ttacagtttg gacgaatcca cctttaaaga aggcctggaa     1740

gtgaaaccaa tattgaacta ctacagagaa aacattgtta gtgaacaggc tcacattctg     1800

gtggactgtg gagaagacaa tctgtgtgtt cctgacttga agctgtcggc tagaccagat     1860

aagcatcagg taatcattgg agatgaaaat caccttatgc tcataataaa tgcaagaaat     1920

gaaggggaag gagcatatga agctgaactc tttgtaatga taccagaaga ggcagattat     1980

gttggaatcg aacgcaacaa caagggattt cgaccactga gctgtgagta caagatggaa     2040

aatgtaacca ggatggtggt gtgtgacctt gggaacccta tggtgtctgg aacaaattat     2100

tccctgggcc tccgatttgc agttccacgt cttgagaaaa caaacatgag cattaacttc     2160

gatctccaaa tcagaagttc caacaaggac aatccagaca gcaattttgt gagcctgcaa     2220

atcaacatca ctgctgtagc gcaggtggaa ataagaggag tgtcacaccc tccgcagatt     2280

gttctgccca ttcataactg ggaaccagaa gaggagcccc acaaagagga ggaggttgga     2340

ccattggtgg aacatattta tgagctgcac aatattggac caagtaccat cagtgacacc     2400

atcctggagg tgggctggcc tttctctgcc cgggatgaat ttcttctcta tattttccat     2460

attcaaactc tgggacctct gcagtgccaa ccaaatccta atatcaatcc acaggatata     2520

aagcctgctg cctccccaga ggacacccct gagctcagcg cctttttgcg aaactctact     2580

attcctcatc ttgtcaggaa gagggatgta catgtggtcg aattccacag acagagccct     2640

gcaaaaatac tgaattgtac aaatatcgag tgtttacaaa tctcctgtgc agtgggacga     2700

ctcgaaggag gagaaagcgc agtcctgaaa gtcaggtcac gattatgggc ccacaccttc     2760

ctccagagaa aaaatgatcc ctatgctctt gcatccctgg tgtcctttga agttaagaag     2820

atgccttata cagatcagcc agcaaaactc ccagaaggaa gcatagcaat taagacatca     2880

gttatttggg caactccgaa tgtttccttc tcaatcccat ta                        2922


<210>  3825
<211>  1608
<212>  DNA
<213>  Homo Sapiens

<400>  3825
tacaacctcg acccgcagcg ccccgtgcac ttccagggcc ccgctgactc gttcttcggc       60

tacgcagttc tggagcattt ccacgacaac acgcgctggg tccttgtggg cgcaccaaag      120

gcagattcca aatacagccc ttcagtgaag tctcctgggg ctgtgtttaa gtgccgtgtt      180

cacaccaacc ctgaccggag atgcaccgaa ctggacatgg ctcgagggaa gaatcggggc      240

acgtcctgcg gaaagacctg ccgggaagac cgcgatgatg agtggatggg ggtgagcctg      300

gcccgacagc ccaaggctga tggccgtgtg ttggcctgtg ctcatcgctg gaagaacatc      360

tactatgaag ccgaccacat cctaccccat ggcttctgct acatcatccc ctccaacctc      420

caggccaaag gcaggacgct gatcccttgc tatgaagagt ataagaagaa gtacggagag      480

gaacacggct cctgccaggc tgggatagcg ggcttcttca ccgaggagct ggtggtgatg      540

ggtgctccag ggtcatttta ttgggctgga accatcaaag tgctgaacct tacggacaac      600

acctatttaa aactgaacga cgaagtgatc atgaacaggc ggtacaccta cctgggctac      660

gcagtgaccg ctggccactt ctctcacccg tccaccattg atgtggtagg aggtgcccca      720

caggacaaag gcatcggcaa ggtttatatt ttcagagctg accgaagatc aggcacctta      780

attaagatct ttcaagcatc aggtaaaaag atgggctctt acttcggctc ctccttgtgc      840

gcagttgacc tgaatgggga cggcctctct gacctgctgg tgggggcccc catgttttct      900

gagatcaggg atgagggaca ggtcactgtc tacatcaaca gaggaaatgg agccctcgag      960

gagcagctgg ctctgactgg ggatggtgcc tacaatgcgc actttggaga gagcattgcc     1020

agcctggacg atctggacaa tgatgggttc ccagatgtgg ccattggtgc acccaaggag     1080

gatgacttcg caggggcggt ctatatctat catggtgatg ccggtgggat agtccctcag     1140

tactcaatga aactgtctgg gcagaagata aatccagtgc tccggatgtt tggtcagtcc     1200

atatcgggag gcattgatat ggatggaaat ggctatcctg atgtcactgt tggagccttc     1260

atgtccgaca gcgtggttct tctcagagca aggcctgtca ttacggtgga tgtctccatc     1320

ttcctcccgg gctccatcaa catcacagcg cctcagtgtc acgacggaca gcagcctgtg     1380

aactgcctga acgtcaccac ctgcttcagc ttccatggca aacacgttcc agaagagatt     1440

ggcctgaatt atgttctgat ggctgacgtg gccaaaaagg agaagggcca gatgcccagg     1500

gtctactttg tgctgctggg agagaccatg ggtcaggtca cagagaagct gcagctgact     1560

tacatggagg agacgtgtcg tcactatgtg gcccatgtga agcggagg                  1608


<210>  3826
<211>  3318
<212>  DNA
<213>  Homo Sapiens

<400>  3826
ttcaatgtgg atgtggcccg gccctggctc acgcccaagg gaggtgcccc tttcgtgctc       60

agctcccttc tgcaccaaga ccccagcacc aaccagacct ggctcctggt caccagcccc      120

agaaccaaga ggacaccagg gcccctccat cgatgttccc ttgtccagga tgaaatcctt      180

tgccatcctg tagagcatgt ccccatcccc aaggggaggc accggggagt gaccgttgtc      240

cggagccacc acggtgtttt gatatgcatt caagtgctgg tccggcggcc tcacagcctc      300

agctcagaac tcacaggcac ctgtagcctc ctgggccctg acctccgtcc ccaggctcag      360

gccaacttct tcgaccttga aaatctcctg gatccagatg cacgtgtgga cactggagac      420

tgctacagca acaaagaagg cggtggagaa gacgatgtga acacagccag gcagcgccgg      480

gctctggaga aggaggagga ggaagacaag gaggaggagg aagacgagga ggaggaggaa      540

gctggcaccg agattgccat catcctggat ggctcaggaa gcattgatcc cccagacttt      600

cagagagcca aagacttcat ctccaacatg atgaggaact tctatgaaaa gtgttttgag      660

tgcaactttg ccttggtgca gtatggagga gtgatccaga ctgagtttga ccttcgggac      720

agccaggatg tgatggcctc cctcgccaga gtccagaaca tcactcaagt ggggagtgtc      780

accaagactg cctcagccat gcaacacgtc ttagacagca tcttcacctc aagccacggc      840

tccaggagaa aggcatccaa ggtcatggtg gtgctcaccg atggtggcat attcgaggac      900

cccctcaacc ttacgacagt catcaactcc cccaaaatgc agggtgttga gcgctttgcc      960

attggggtgg gagaagaatt taagagtgct aggactgcga gggaactgaa cctgatcgcc     1020

tcagacccgg atgagaccca tgctttcaag gtgaccaact acatggcgct ggatgggctg     1080

ctgagcaaac tgcggtacaa catcatcagc atggaaggca cggttggaga cgcccttcac     1140

taccagctgg cacagattgg cttcagtgct cagatcctgg atgagcggca ggtgctgctc     1200

ggcgccgtcg gggcctttga ctggtccgga ggggcgttgc tctacgacac acgcagccgc     1260

cggggccgct tcctgaacca gacagcggcg gcggcggcag acgcggaggc tgcgcagtac     1320

agctacctgg gttacgctgt ggccgtgctg cacaagacct gcagcctctc ctacgtcgcg     1380

ggggctccac agtacaaaca tcatggggcc gtgtttgagc tccagaagga gggcagagag     1440

gccagcttcc tgccagtgct ggagggagag cagatggggt cctattttgg ctctgagctg     1500

tgccctgtgg acattgacat ggatggaagc acggacttct tgctggtggc tgctccattt     1560

taccacgttc atggagaaga aggcagagtc tacgtgtacc gtctcagcga gcaggatggt     1620

tctttctcct tggcacgcat actgagtggg caccccgggt tcaccaatgc ccgctttggc     1680

tttgccatgg cggctatggg ggatctcagt caggataagc tcacagatgt ggccatcggg     1740

gcccccctgg aaggttttgg ggcagatgat ggtgccagct tcggcagtgt gtatatctac     1800

aatggacact gggacggcct ctccgccagc ccctcgcagc ggatcagagc ctccacggtg     1860

gccccaggac tccagtactt cggcatgtcc atggctggtg gctttgatat tagtggcgac     1920

ggccttgccg acatcaccgt gggcactctg ggccaggcgg ttgtgttccg ctcccggcct     1980

gtggttcgcc tgaaggtctc catggccttc acccccagcg cactgcccat cggcttcaac     2040

ggcgtcgtga atgtccgttt atgttttgaa atcagctctg taaccacagc ctctgagtca     2100

ggcctccgtg aggcacttct caacttcacg ctggatgtgg atgtggggaa gcagaggaga     2160

cggctgcagt gttcagacgt aagaagctgt ctgggctgcc tgagggagtg gagcagcgga     2220

tcccagcttt gtgaggacct cctgctcatg cccacagagg gagagctctg tgaggaggac     2280

tgcttctcca atgccagtgt caaagtcagc taccagctcc agacccctga gggacagacg     2340

gaccatcccc agcccatcct ggaccgctac actgagccct ttgccatctt ccagctgccc     2400

tatgagaagg cctgcaagaa taagctgttt tgtgtcgcag aattacagtt ggccaccacc     2460

gtctctcagc aggagttggt ggtgggtctc acaaaggagc tgaccctgaa cattaaccta     2520

actaactccg gggaagattc ctacatgaca agcatggcct tgaattaccc cagaaacctg     2580

cagttgaaga ggatgcaaaa gcctccctct ccaaacattc agtgtgatga ccctcagccg     2640

gttgcttctg tcctgatcat gaactgcagg attggtcacc ccgtcctcaa gaggtcatct     2700

gctcatgttt cagtcgtttg gcagctagag gagaatgcct ttccaaacag gacagcagac     2760

atcactgtga ctgtcaccaa ttccaatgaa agacggtctt tggccaacga gacccacacc     2820

cttcaattca ggcatggctt cgttgcagtt ctgtccaaac catccataat gtacgtgaac     2880

acaggccagg ggctttctca ccacaaagaa ttcctcttcc atgtacatgg ggagaacctc     2940

tttggagcag aataccagtt gcaaatttgc gtcccaacca aattacgagg tctccaggtt     3000

gcagcagtga agaagctgac gaggactcag gcctccacgg tgtgcacctg gagtcaggag     3060

cgcgcttgtg cgtacagttc ggttcagcat gtggaagaat ggcattcagt gagctgtgtc     3120

atcgcttcag ataaagaaaa tgtcaccgtg gctgcagaga tctcctggga tcactctgag     3180

gagttactaa aagatgtaac tgaactgcag atccttggtg aaatatcttt caacaaatct     3240

ctatatgagg gactgaatgc agagaaccac agaactaaga tcactgtcgt cttcctgaaa     3300

gatgagaagt accattct                                                   3318


<210>  3827
<211>  2943
<212>  DNA
<213>  Homo Sapiens

<400>  3827
tacaacctgg acgtgcgggg cgcgcggagc ttctccccac cgcgcgccgg gaggcacttt       60

ggataccgcg tcctgcaggt cggaaacggg gtcatcgtgg gagctccagg ggaggggaac      120

agcacaggaa gcctctatca gtgccagtcg ggcacaggac actgcctgcc agtcaccctg      180

agaggttcca actatacctc caagtacttg ggaatgacct tggcaacaga ccccacagat      240

ggaagcattt tgtttgctgc tgttcagttt tccacaagct acaaaacaga atttgatttc      300

tcagattatg ttaaacggaa ggaccctgat gctctgctga agcatgtaaa gcacatgttg      360

ctgttgacca atacctttgg tgccatcaat tatgtcgcga cagaggtgtt ccgggaggag      420

ctgggggccc ggccagatgc caccaaagtg cttatcatca tcacggatgg ggaggccact      480

gacagtggca acatcgatgc ggccaaagac atcatccgct acatcatcgg gattggaaag      540

cattttcaga ccaaggagag tcaggagacc ctccacaaat ttgcatcaaa acccgcgagc      600

gagtttgtga aaattctgga cacatttgag aagctgaaag atctattcac tgagctgcag      660

aagaagatct atgtcattga gggcacaagc aaacaggacc tgacttcctt caacatggag      720

ctgtcctcca gcggcatcag tgctgacctc agcaggggcc atgcagtcgt gggggcagta      780

ggagccaagg actgggctgg gggctttctt gacctgaagg cagacctgca ggatgacaca      840

tttattggga atgaaccatt gacaccagaa gtgagagcag gctatttggg ttacaccgtg      900

acctggctgc cctcccggca aaagacttcg ttgctggcct cgggagcccc tcgataccag      960

cacatgggcc gagtgctgct gttccaagag ccacagggcg gaggacactg gagccaggtc     1020

cagacaatcc atgggaccca gattggctct tatttcggtg gggagctgtg tggcgtcgac     1080

gtggaccaag atggggagac agagctgctg ctgattggtg ccccactgtt ctatggggag     1140

cagagaggag gccgggtgtt tatctaccag agaagacagt tggggtttga agaagtctca     1200

gagctgcagg gggaccccgg ctacccactc gggcggtttg gagaagccat cactgctctg     1260

acagacatca acggcgatgg gctggtagac gtggctgtgg gggcccctct ggaggagcag     1320

ggggctgtgt acatcttcaa tgggaggcac ggggggctta gtccccagcc aagtcagcgg     1380

atagaaggga cccaagtgct ctcaggaatt cagtggtttg gacgctccat ccatggggtg     1440

aaggaccttg aaggggatgg cttggcagat gtggctgtgg gggctgagag ccagatgatc     1500

gtgctgagct cccggcccgt ggtggatatg gtcaccctga tgtccttctc tccagctgag     1560

atcccagtgc atgaagtgga gtgctcctat tcaaccagta acaagatgaa agaaggagtt     1620

aatatcacaa tctgtttcca gatcaagtct ctcatccccc agttccaagg ccgcctggtt     1680

gccaatctca cttacactct gcagctggat ggccaccgga ccagaagacg ggggttgttc     1740

ccaggaggga gacatgaact cagaaggaat atagctgtca ccaccagcat gtcatgcact     1800

gacttctcat ttcatttccc ggtatgtgtt caagacctca tctcccccat caatgtttcc     1860

ctgaatttct ctctttggga ggaggaaggg acaccgaggg accaaagggc gggcaaggac     1920

ataccgccca tcctgagacc ctccctgcac tcggaaacct gggagatccc ttttgagaag     1980

aactgtgggg aggacaagaa gtgtgaggca aacttgagag tgtccttctc tcctgcaaga     2040

tccagagccc tgcgtctaac tgcttttgcc agcctctctg tggagctgag cctgagtaac     2100

ttggaagaag atgcttactg ggtccagctg gacctgcact tccccccggg actctccttc     2160

cgcaaggtgg agatgctgaa gccccatagc cagatacctg tgagctgcga ggagcttcct     2220

gaagagtcca ggcttctgtc cagggcatta tcttgcaatg tgagctctcc catcttcaaa     2280

gcaggccact cggttgctct gcagatgatg tttaatacac tggtaaacag ctcctggggg     2340

gactcggttg aattgcacgc caatgtgacc tgtaacaatg aggactcaga cctcctggag     2400

gacaactcag ccactaccat catccccatc ctgtacccca tcaacatcct catccaggac     2460

caagaagact ccacactcta tgtcagtttc acccccaaag gccccaagat ccaccaagtc     2520

aagcacatgt accaggtgag gatccagcct tccatccacg accacaacat acccaccctg     2580

gaggctgtgg ttggggtgcc acagcctccc agcgaggggc ccatcacaca ccagtggagc     2640

gtgcagatgg agcctcccgt gccctgccac tatgaggatc tggagaggct cccggatgca     2700

gctgagcctt gtctccccgg agccctgttc cgctgccctg ttgtcttcag gcaggagatc     2760

ctcgtccaag tgatcgggac tctggagctg gtgggagaga tcgaggcctc ttccatgttc     2820

agcctctgca gctccctctc catctccttc aacagcagca agcatttcca cctctatggc     2880

agcaacgcct ccctggccca ggttgtcatg aaggttgacg tggtgtatga gaagcagatg     2940

ctc                                                                   2943


<210>  3828
<211>  3264
<212>  DNA
<213>  Homo Sapiens

<400>  3828
ttcaacttgg acactgaaaa cgcaatgacc ttccaagaga acgcaagggg cttcgggcag       60

agcgtggtcc agcttcaggg atccagggtg gtggttggag ccccccagga gatagtggct      120

gccaaccaaa ggggcagcct ctaccagtgc gactacagca caggctcatg cgagcccatc      180

cacctgcagg tccccgtgga ggccgtgaac atgtccctgg gcctgtccct ggcagccacc      240

accagccccc ctcagctgct ggcctgtggt cccaccgtgc accagacttg cagtgagaac      300

acgtatgtga aagggctctg cttcctgttt ggatccaacc tacggcagca gccccagaag      360

ttcccagagg ccctccgagg gtgtcctcaa gaggatagtg acattgcctt cttgattgat      420

ggctctggta gcatcatccc acatgacttt cggcggatga aggagtttgt ctcaactgtg      480

atggagcaat taaaaaagtc caaaaccttg ttctctttga tgcagtactc tgaagaattc      540

cggattcact ttaccttcaa agagttccag aacaacccta acccaagatc actggtgaag      600

ccaataacgc agctgcttgg gcggacacac acggccacgg gcatccgcaa agtggtacga      660

gagctgttta acatcaccaa cggagcccga aagaatgcct ttaagatcct agttgtcatc      720

acggatggag aaaagtttgg cgatcccttg ggatatgagg atgtcatccc tgaggcagac      780

agagagggag tcattcgcta cgtcattggg gtgggagatg ccttccgcag tgagaaatcc      840

cgccaagagc ttaataccat cgcatccaag ccgcctcgtg atcacgtgtt ccaggtgaat      900

aactttgagg ctctgaagac cattcagaac cagcttcggg agaagatctt tgcgatcgag      960

ggtactcaga caggaagtag cagctccttt gagcatgaga tgtctcagga aggcttcagc     1020

gctgccatca cctctaatgg ccccttgctg agcactgtgg ggagctatga ctgggctggt     1080

ggagtctttc tatatacatc aaaggagaaa agcaccttca tcaacatgac cagagtggat     1140

tcagacatga atgatgctta cttgggttat gctgccgcca tcatcttacg gaaccgggtg     1200

caaagcctgg ttctgggggc acctcgatat cagcacatcg gcctggtagc gatgttcagg     1260

cagaacactg gcatgtggga gtccaacgct aatgtcaagg gcacccagat cggcgcctac     1320

ttcggggcct ccctctgctc cgtggacgtg gacagcaacg gcagcaccga cctggtcctc     1380

atcggggccc cccattacta cgagcagacc cgagggggcc aggtgtccgt gtgccccttg     1440

cccaggggga gggctcggtg gcagtgtgat gctgttctct acggggagca gggccaaccc     1500

tggggccgct ttggggcagc cctaacagtg ctgggggacg taaatgggga caagctgacg     1560

gacgtggcca ttggggcccc aggagaggag gacaaccggg gtgctgttta cctgtttcac     1620

ggaacctcag gatctggcat cagcccctcc catagccagc ggatagcagg ctccaagctc     1680

tctcccaggc tccagtattt tggtcagtca ctgagtgggg gccaggacct cacaatggat     1740

ggactggtag acctgactgt aggagcccag gggcacgtgc tgctgctcag gtcccagcca     1800

gtactgagag tcaaggcaat catggagttc aatcccaggg aagtggcaag gaatgtattt     1860

gagtgtaatg atcaggtggt gaaaggcaag gaagccggag aggtcagagt ctgcctccat     1920

gtccagaaga gcacacggga tcggctaaga gaaggacaga tccagagtgt tgtgacttat     1980

gacctggctc tggactccgg ccgcccacat tcccgcgccg tcttcaatga gacaaagaac     2040

agcacacgca gacagacaca ggtcttgggg ctgacccaga cttgtgagac cctgaaacta     2100

cagttgccga attgcatcga ggacccagtg agccccattg tgctgcgcct gaacttctct     2160

ctggtgggaa cgccattgtc tgctttcggg aacctccggc cagtgctggc ggaggatgct     2220

cagagactct tcacagcctt gtttcccttt gagaagaatt gtggcaatga caacatctgc     2280

caggatgacc tcagcatcac cttcagtttc atgagcctgg actgcctcgt ggtgggtggg     2340

ccccgggagt tcaacgtgac agtgactgtg agaaatgatg gtgaggactc ctacaggaca     2400

caggtcacct tcttcttccc gcttgacctg tcctaccgga aggtgtccac gctccagaac     2460

cagcgctcac agcgatcctg gcgcctggcc tgtgagtctg cctcctccac cgaagtgtct     2520

ggggtcttga agagcaccag ctgcagcata aaccacccca tcttcccgga aaactcagag     2580

gtcaccttta atatcacgtt tgatgtagac tctaaggctt cccttggaaa caaactgctc     2640

ctcaaggcca atgtgaccag tgagaacaac atgcccagaa ccaacaaaac cgaattccaa     2700

ctggagctgc cggtgaaata tgctgtctac atggtggtca ccagccatgg ggtctccact     2760

aaatatctca acttcacggc ctcagagaat accagtcggg tcatgcagca tcaatatcag     2820

gtcagcaacc tggggcagag gagcctcccc atcagcctgg tgttcttggt gcccgtccgg     2880

ctgaaccaga ctgtcatatg ggaccgcccc caggtcacct tctccgagaa cctctcgagt     2940

acgtgccaca ccaaggagcg cttgccctct cactccgact ttctggctga gcttcggaag     3000

gcccccgtgg tgaactgctc catcgctgtc tgccagagaa tccagtgtga catcccgttc     3060

tttggcatcc aggaagaatt caatgctacc ctcaaaggca acctctcgtt tgactggtac     3120

atcaagacct cgcataacca cctcctgatc gtgagcacag ctgagatctt gtttaacgat     3180

tccgtgttca ccctgctgcc gggacagggg gcgtttgtga ggtcccagac ggagaccaaa     3240

gtggagccgt tcgaggtccc caac                                            3264


<210>  3829
<211>  2886
<212>  DNA
<213>  Homo Sapiens

<400>  3829
ttcaacctag acgtggacag tcctgccgag tactctggcc ccgagggaag ttacttcggc       60

ttcgccgtgg atttcttcgt gcccagcgcg tcttcccgga tgtttcttct cgtgggagct      120

cccaaagcaa acaccaccca gcctgggatt gtggaaggag ggcaggtcct caaatgtgac      180

tggtcttcta cccgccggtg ccagccaatt gaatttgatg caacaggcaa tagagattat      240

gccaaggatg atccattgga atttaagtcc catcagtggt ttggagcatc tgtgaggtcg      300

aaacaggata aaattttggc ctgtgcccca ttgtaccatt ggagaactga gatgaaacag      360

gagcgagagc ctgttggaac atgctttctt caagatggaa caaagactgt tgagtatgct      420

ccatgtagat cacaagatat tgatgctgat ggacagggat tttgtcaagg aggattcagc      480

attgatttta ctaaagctga cagagtactt cttggtggtc ctggtagctt ttattggcaa      540

ggtcagctta tttcggatca agtggcagaa atcgtatcta aatacgaccc caatgtttac      600

agcatcaagt ataataacca attagcaact cggactgcac aagctatttt tgatgacagc      660

tatttgggtt attctgtggc tgtcggagat ttcaatggtg atggcataga tgactttgtt      720

tcaggagttc caagagcagc aaggactttg ggaatggttt atatttatga tgggaagaac      780

atgtcctcct tatacaattt tactggcgag cagatggctg catatttcgg attttctgta      840

gctgccactg acattaatgg agatgattat gcagatgtgt ttattggagc acctctcttc      900

atggatcgtg gctctgatgg caaactccaa gaggtggggc aggtctcagt gtctctacag      960

agagcttcag gagacttcca gacgacaaag ctgaatggat ttgaggtctt tgcacggttt     1020

ggcagtgcca tagctccttt gggagatctg gaccaggatg gtttcaatga tattgcaatt     1080

gctgctccat atgggggtga agataaaaaa ggaattgttt atatcttcaa tggaagatca     1140

acaggcttga acgcagtccc atctcaaatc cttgaagggc agtgggctgc tcgaagcatg     1200

ccaccaagct ttggctattc aatgaaagga gccacagata tagacaaaaa tggatatcca     1260

gacttaattg taggagcttt tggtgtagat cgagctatct tatacagggc cagaccagtt     1320

atcactgtaa atgctggtct tgaagtgtac cctagcattt taaatcaaga caataaaacc     1380

tgctcactgc ctggaacagc tctcaaagtt tcctgtttta atgttaggtt ctgcttaaag     1440

gcagatggca aaggagtact tcccaggaaa cttaatttcc aggtggaact tcttttggat     1500

aaactcaagc aaaagggagc aattcgacga gcactgtttc tctacagcag gtccccaagt     1560

cactccaaga acatgactat ttcaaggggg ggactgatgc agtgtgagga attgatagcg     1620

tatctgcggg atgaatctga atttagagac aaactcactc caattactat ttttatggaa     1680

tatcggttgg attatagaac agctgctgat acaacaggct tgcaacccat tcttaaccag     1740

ttcacgcctg ctaacattag tcgacaggct cacattctac ttgactgtgg tgaagacaat     1800

gtctgtaaac ccaagctgga agtttctgta gatagtgatc aaaagaagat ctatattggg     1860

gatgacaacc ctctgacatt gattgttaag gctcagaatc aaggagaagg tgcctacgaa     1920

gctgagctca tcgtttccat tccactgcag gctgatttca tcggggttgt ccgaaacaat     1980

gaagccttag caagactttc ctgtgcattt aagacagaaa accaaactcg ccaggtggta     2040

tgtgaccttg gaaacccaat gaaggctgga actcaactct tagctggtct tcgtttcagt     2100

gtgcaccagc agtcagagat ggatacttct gtgaaatttg acttacaaat ccaaagctca     2160

aatctatttg acaaagtaag cccagttgta tctcacaaag ttgatcttgc tgttttagct     2220

gcagttgaga taagaggagt ctcgagtcct gatcatatct ttcttccgat tccaaactgg     2280

gagcacaagg agaaccctga gactgaagaa gatgttgggc cagttgttca gcacatctat     2340

gagctgagaa acaatggtcc aagttcattc agcaaggcaa tgctccatct tcagtggcct     2400

tacaaatata ataataacac tctgttgtat atccttcatt atgatattga tggaccaatg     2460

aactgcactt cagatatgga gatcaaccct ttgagaatta agatctcatc tttgcaaaca     2520

actgaaaaga atgacacggt tgccgggcaa ggtgagcggg accatctcat cactaagcgg     2580

gatcttgccc tcagtgaagg agatattcac actttgggtt gtggagttgc tcagtgcttg     2640

aagattgtct gccaagttgg gagattagac agaggaaaga gtgcaatctt gtacgtaaag     2700

tcattactgt ggactgagac ttttatgaat aaagaaaatc agaatcattc ctattctctg     2760

aagtcgtctg cttcatttaa tgtcatagag tttccttata agaatcttcc aattgaggat     2820

atcaccaact ccacattggt taccactaat gtcacctggg gcattcagcc agcgcccatg     2880

cctgtg                                                                2886


<210>  3830
<211>  3264
<212>  DNA
<213>  Homo Sapiens

<400>  3830
ttcaacttgg acacagagga gctgacagcc ttccgtgtgg acagcgctgg gtttggagac       60

agcgtggtcc agtatgccaa ctcctgggtg gtggttggag ccccccaaaa gataacagct      120

gccaaccaaa cgggtggcct ctaccagtgt ggctacagca ctggtgcctg tgagcccatc      180

ggcctgcagg tgcccccgga ggccgtgaac atgtccctgg gcctgtccct ggcgtctacc      240

accagccctt cccagctgct ggcctgcggc cccaccgtgc accacgagtg cgggaggaac      300

atgtacctca ccggactctg cttcctcctg ggccccaccc agctcaccca gaggctcccg      360

gtgtccaggc aggagtgccc aagacaggag caggacattg tgttcctgat cgatggctca      420

ggcagcatct cctcccgcaa ctttgccacg atgatgaact tcgtgagagc tgtgataagc      480

cagttccaga gacccagcac ccagttttcc ctgatgcagt tctccaacaa attccaaaca      540

cacttcactt tcgaggaatt caggcgcagc tcaaaccccc tcagcctgtt ggcttctgtt      600

caccagctgc aagggtttac atacacggcc accgccatcc aaaatgtcgt gcaccgattg      660

ttccatgcct catatggggc ccgtagggat gccgccaaaa ttctcattgt catcactgat      720

gggaagaaag aaggcgacag cctggattat aaggatgtca tccccatggc tgatgcagca      780

ggcatcatcc gctatgcaat tggggttgga ttagcttttc aaaacagaaa ttcttggaaa      840

gaattaaatg acattgcatc gaagccctcc caggaacaca tatttaaagt ggaggacttt      900

gatgctctga aagatattca aaaccaactg aaggagaaga tctttgccat tgagggtacg      960

gagaccacaa gcagtagctc cttcgaattg gagatggcac aggagggctt cagcgctgtg     1020

ttcacacctg atggccccgt tctgggggct gtggggagct tcacctggtc tggaggtgcc     1080

ttcctgtacc ccccaaatat gagccctacc ttcatcaaca tgtctcagga gaatgtggac     1140

atgagggact cttacctggg ttactccacc gagctggccc tctggaaagg ggtgcagagc     1200

ctggtcctgg gggccccccg ctaccagcac accgggaagg ctgtcatctt cacccaggtg     1260

tccaggcaat ggaggatgaa ggccgaagtc acggggactc agatcggctc ctacttcggg     1320

gcctccctct gctccgtgga cgtagacagc gacggcagca ccgacctggt cctcatcggg     1380

gccccccatt actacgagca gacccgaggg ggccaggtgt ctgtgtgtcc cttgcccagg     1440

gggtggagaa ggtggtggtg tgatgctgtt ctctacgggg agcagggcca cccctggggt     1500

cgctttgggg cggctctgac agtgctgggg gatgtgaatg gggacaagct gacagacgtg     1560

gtcatcgggg ccccaggaga gaaggagaac cggggtgctg tctacctgtt tcacggagtc     1620

ttgggaccca gcatcagccc ctcccacagc cagcggatcg cgggctccca gctctcctcc     1680

aggctgcagt attttgggca ggcactgagc gggggtcaag acctcaccca ggatggactg     1740

gtggacctgg ctgtgggggc ccggggccag gtgctcctgc tcaggaccag acctgtgctc     1800

tgggtggggg tgagcatgca gttcatacct gccgagatcc ccaggtctgc gtttgagtgt     1860

cgggagcagg tggtctctga gcagaccctg gtacagtcca acatctgcct ttacattgac     1920

aaacgttcta agaacctgct tgggagccgt gacctccaaa gctctgtgac cttggacctg     1980

gccctcgacc ctggccgcct gagtccccgt gccaccttcc aggaaacaaa gaaccggagt     2040

ctgagccgag tccgagtcct cgggctgaag gcacactgtg aaaacttcaa cctgctgctc     2100

ccgagctgcg tggaggactc tgtgaccccc attaccttgc gtctgaactt cacgctggtg     2160

ggcaagcccc tccttgcctt cagaaacctg cggcctatgc tggccgccga tgctcagaga     2220

tacttcacgg cctccctacc ctttgagaag aactgtggag ccgaccatat ctgccaggac     2280

aatctcggca tctccttcag cttcccaggc ttgaagtccc tgctggtggg gagtaacctg     2340

gagctgaacg cagaagtgat ggtgtggaat gacggggaag actcctacgg aaccaccgtc     2400

accttctccc accccgcagg actgtcctac cgctacgtgg cagagggcca gaaacaaggg     2460

cagctgcgtt ccctgcacct gacatgtgac agcgccccag ttgggagcca gggcacctgg     2520

agcaccagct gcagaatcaa ccacctcatc ttccgtggcg gcgcccagat caccttcttg     2580

gctacctttg acgtctcccc caaggctgtc ctgggagacc ggctgcttct gacagccaat     2640

gtgagcagtg agaacaacac tcccaggacc agcaagacca ccttccagct ggagctcccg     2700

gtgaagtatg ctgtctacac tgtggttagc agccacgaac aattcaccaa atacctcaac     2760

ttctcagagt ctgaggagaa ggaaagccat gtggccatgc acagatacca ggtcaataac     2820

ctgggacaga gggacctgcc tgtcagcatc aacttctggg tgcctgtgga gctgaaccag     2880

gaggctgtgt ggatggatgt ggaggtctcc cacccccaga acccatccct tcggtgctcc     2940

tcagagaaaa tcgcaccccc agcatctgac ttcctggcgc acattcagaa gaatcccgtg     3000

ctggactgct ccattgctgg ctgcctgcgg ttccgctgtg acgtcccctc cttcagcgtc     3060

caggaggagc tggatttcac cctgaagggc aacctcagct ttggctgggt ccgccagata     3120

ttgcagaaga aggtgtcggt cgtgagtgtg gctgaaatta cgttcgacac atccgtgtac     3180

tcccagcttc caggacagga ggcatttatg agagctcaga cgacaacggt gctggagaag     3240

tacaaggtcc acaaccccac cccc                                            3264


<210>  3831
<211>  2124
<212>  DNA
<213>  Homo Sapiens

<400>  3831
caaacagatg aaaatagatg tttaaaagca aatgccaaat catgtggaga atgtatacaa       60

gcagggccaa attgtgggtg gtgcacaaat tcaacatttt tacaggaagg aatgcctact      120

tctgcacgat gtgatgattt agaagcctta aaaaagaagg gttgccctcc agatgacata      180

gaaaatccca gaggctccaa agatataaag aaaaataaaa atgtaaccaa ccgtagcaaa      240

ggaacagcag agaagctcaa gccagaggat attactcaga tccaaccaca gcagttggtt      300

ttgcgattaa gatcagggga gccacagaca tttacattaa aattcaagag agctgaagac      360

tatcccattg acctctacta ccttatggac ctgtcttact caatgaaaga cgatttggag      420

aatgtaaaaa gtcttggaac agatctgatg aatgaaatga ggaggattac ttcggacttc      480

agaattggat ttggctcatt tgtggaaaag actgtgatgc cttacattag cacaacacca      540

gctaagctca ggaacccttg cacaagtgaa cagaactgca ccagcccatt tagctacaaa      600

aatgtgctca gtcttactaa taaaggagaa gtatttaatg aacttgttgg aaaacagcgc      660

atatctggaa atttggattc tccagaaggt ggtttcgatg ccatcatgca agttgcagtt      720

tgtggatcac tgattggctg gaggaatgtt acacggctgc tggtgttttc cacagatgcc      780

gggtttcact ttgctggaga tgggaaactt ggtggcattg ttttaccaaa tgatggacaa      840

tgtcacctgg aaaataatat gtacacaatg agccattatt atgattatcc ttctattgct      900

caccttgtcc agaaactgag tgaaaataat attcagacaa tttttgcagt tactgaagaa      960

tttcagcctg tttacaagga gctgaaaaac ttgatcccta agtcagcagt aggaacatta     1020

tctgcaaatt ctagcaatgt aattcagttg atcattgatg catacaattc cctttcctca     1080

gaagtcattt tggaaaacgg caaattgtca gaaggagtaa caataagtta caaatcttac     1140

tgcaagaacg gggtgaatgg aacaggggaa aatggaagaa aatgttccaa tatttccatt     1200

ggagatgagg ttcaatttga aattagcata acttcaaata agtgtccaaa aaaggattct     1260

gacagcttta aaattaggcc tctgggcttt acggaggaag tagaggttat tcttcagtac     1320

atctgtgaat gtgaatgcca aagcgaaggc atccctgaaa gtcccaagtg tcatgaagga     1380

aatgggacat ttgagtgtgg cgcgtgcagg tgcaatgaag ggcgtgttgg tagacattgt     1440

gaatgcagca cagatgaagt taacagtgaa gacatggatg cttactgcag gaaagaaaac     1500

agttcagaaa tctgcagtaa caatggagag tgcgtctgcg gacagtgtgt ttgtaggaag     1560

agggataata caaatgaaat ttattctggc aaattctgcg agtgtgataa tttcaactgt     1620

gatagatcca atggcttaat ttgtggagga aatggtgttt gcaagtgtcg tgtgtgtgag     1680

tgcaacccca actacactgg cagtgcatgt gactgttctt tggatactag tacttgtgaa     1740

gccagcaacg gacagatctg caatggccgg ggcatctgtg agtgtggtgt ctgtaagtgt     1800

acagatccga agtttcaagg gcaaacgtgt gagatgtgtc agacctgcct tggtgtctgt     1860

gctgagcata aagaatgtgt tcagtgcaga gccttcaata aaggagaaaa gaaagacaca     1920

tgcacacagg aatgttccta ttttaacatt accaaggtag aaagtcggga caaattaccc     1980

cagccggtcc aacctgatcc tgtgtcccat tgtaaggaga aggatgttga cgactgttgg     2040

ttctatttta cgtattcagt gaatgggaac aacgaggtca tggttcatgt tgtggagaat     2100

ccagagtgtc ccactggtcc agac                                            2124


<210>  3832
<211>  2034
<212>  DNA
<213>  Homo Sapiens

<400>  3832
caggagtgca cgaagttcaa ggtcagcagc tgccgggaat gcatcgagtc ggggcccggc       60

tgcacctggt gccagaagct gaacttcaca gggccggggg atcctgactc cattcgctgc      120

gacacccggc cacagctgct catgaggggc tgtgcggctg acgacatcat ggaccccaca      180

agcctcgctg aaacccagga agaccacaat gggggccaga agcagctgtc cccacaaaaa      240

gtgacgcttt acctgcgacc aggccaggca gcagcgttca acgtgacctt ccggcgggcc      300

aagggctacc ccatcgacct gtactatctg atggacctct cctactccat gcttgatgac      360

ctcaggaatg tcaagaagct aggtggcgac ctgctccggg ccctcaacga gatcaccgag      420

tccggccgca ttggcttcgg gtccttcgtg gacaagaccg tgctgccgtt cgtgaacacg      480

caccctgata agctgcgaaa cccatgcccc aacaaggaga aagagtgcca gcccccgttt      540

gccttcaggc acgtgctgaa gctgaccaac aactccaacc agtttcagac cgaggtcggg      600

aagcagctga tttccggaaa cctggatgca cccgagggtg ggctggacgc catgatgcag      660

gtcgccgcct gcccggagga aatcggctgg cgcaacgtca cgcggctgct ggtgtttgcc      720

actgatgacg gcttccattt cgcgggcgac gggaagctgg gcgccatcct gacccccaac      780

gacggccgct gtcacctgga ggacaacttg tacaagagga gcaacgaatt cgactaccca      840

tcggtgggcc agctggcgca caagctggct gaaaacaaca tccagcccat cttcgcggtg      900

accagtagga tggtgaagac ctacgagaaa ctcaccgaga tcatccccaa gtcagccgtg      960

ggggagctgt ctgaggactc cagcaatgtg gtccatctca ttaagaatgc ttacaataaa     1020

ctctcctcca gggtattcct ggatcacaac gccctccccg acaccctgaa agtcacctac     1080

gactccttct gcagcaatgg agtgacgcac aggaaccagc ccagaggtga ctgtgatggc     1140

gtgcagatca atgtcccgat caccttccag gtgaaggtca cggccacaga gtgcatccag     1200

gagcagtcgt ttgtcatccg ggcgctgggc ttcacggaca tagtgaccgt gcaggtcctt     1260

ccccagtgtg agtgccggtg ccgggaccag agcagagacc gcagcctctg ccatggcaag     1320

ggcttcttgg agtgcggcat ctgcaggtgt gacactggct acattgggaa aaactgtgag     1380

tgccagacac agggccggag cagccaggag ctggaaggaa gctgccggaa ggacaacaac     1440

tccatcatct gctcagggct gggggactgt gtctgcgggc agtgcctgtg ccacaccagc     1500

gacgtccccg gcaagctgat atacgggcag tactgcgagt gtgacaccat caactgtgag     1560

cgctacaacg gccaggtctg cggcggcccg gggagggggc tctgcttctg cgggaagtgc     1620

cgctgccacc cgggctttga gggctcagcg tgccagtgcg agaggaccac tgagggctgc     1680

ctgaacccgc ggcgtgttga gtgtagtggt cgtggccggt gccgctgcaa cgtatgcgag     1740

tgccattcag gctaccagct gcctctgtgc caggagtgcc ccggctgccc ctcaccctgt     1800

ggcaagtaca tctcctgcgc cgagtgcctg aagttcgaaa agggcccctt tgggaagaac     1860

tgcagcgcgg cgtgtccggg cctgcagctg tcgaacaacc ccgtgaaggg caggacctgc     1920

aaggagaggg actcagaggg ctgctgggtg gcctacacgc tggagcagca ggacgggatg     1980

gaccgctacc tcatctatgt ggatgagagc cgagagtgtg tggcaggccc caac           2034


<210>  3833
<211>  2076
<212>  DNA
<213>  Homo Sapiens

<400>  3833
gggcccaaca tctgtaccac gcgaggtgtg agctcctgcc agcagtgcct ggctgtgagc       60

cccatgtgtg cctggtgctc tgatgaggcc ctgcctctgg gctcacctcg ctgtgacctg      120

aaggagaatc tgctgaagga taactgtgcc ccagaatcca tcgagttccc agtgagtgag      180

gcccgagtac tagaggacag gcccctcagc gacaagggct ctggagacag ctcccaggtc      240

actcaagtca gtccccagag gattgcactc cggctccggc cagatgattc gaagaatttc      300

tccatccaag tgcggcaggt ggaggattac cctgtggaca tctactactt gatggacctg      360

tcttactcca tgaaggatga tctgtggagc atccagaacc tgggtaccaa gctggccacc      420

cagatgcgaa agctcaccag taacctgcgg attggcttcg gggcatttgt ggacaagcct      480

gtgtcaccat acatgtatat ctccccacca gaggccctcg aaaacccctg ctatgatatg      540

aagaccacct gcttgcccat gtttggctac aaacacgtgc tgacgctaac tgaccaggtg      600

acccgcttca atgaggaagt gaagaagcag agtgtgtcac ggaaccgaga tgccccagag      660

ggtggctttg atgccatcat gcaggctaca gtctgtgatg aaaagattgg ctggaggaat      720

gatgcatccc acttgctggt gtttaccact gatgccaaga ctcatatagc attggacgga      780

aggctggcag gcattgtcca gcctaatgac gggcagtgtc atgttggtag tgacaatcat      840

tactctgcct ccactaccat ggattatccc tctttggggc tgatgactga gaagctatcc      900

cagaaaaaca tcaatttgat ctttgcagtg actgaaaatg tagtcaatct ctatcagaac      960

tatagtgagc tcatcccagg gaccacagtt ggggttctgt ccatggattc cagcaatgtc     1020

ctccagctca ttgttgatgc ttatgggaaa atccgttcta aagtagagct ggaagtgcgt     1080

gacctccctg aagagttgtc tctatccttc aatgccacct gcctcaacaa tgaggtcatc     1140

cctggcctca agtcttgtat gggactcaag attggagaca cggtgagctt cagcattgag     1200

gccaaggtgc gaggctgtcc ccaggagaag gagaagtcct ttaccataaa gcccgtgggc     1260

ttcaaggaca gcctgatcgt ccaggtcacc tttgattgtg actgtgcctg ccaggcccaa     1320

gctgaaccta atagccatcg ctgcaacaat ggcaatggga cctttgagtg tggggtatgc     1380

cgttgtgggc ctggctggct gggatcccag tgtgagtgct cagaggagga ctatcgccct     1440

tcccagcagg acgaatgcag cccccgggag ggtcagcccg tctgcagcca gcggggcgag     1500

tgcctctgtg gtcaatgtgt ctgccacagc agtgactttg gcaagatcac gggcaagtac     1560

tgcgagtgtg acgacttctc ctgtgtccgc tacaaggggg agatgtgctc aggccatggc     1620

cagtgcagct gtggggactg cctgtgtgac tccgactgga ccggctacta ctgcaactgt     1680

accacgcgta ctgacacctg catgtccagc aatgggctgc tgtgcagcgg ccgcggcaag     1740

tgtgaatgtg gcagctgtgt ctgtatccag ccgggctcct atggggacac ctgtgagaag     1800

tgccccacct gcccagatgc ctgcaccttt aagaaagaat gtgtggagtg taagaagttt     1860

gaccggggag ccctacatga cgaaaatacc tgcaaccgtt actgccgtga cgagattgag     1920

tcagtgaaag agcttaagga cactggcaag gatgcagtga attgtaccta taagaatgag     1980

gatgactgtg tcgtcagatt ccagtactat gaagattcta gtggaaagtc catcctgtat     2040

gtggtagaag agccagagtg tcccaagggc cctgac                               2076


<210>  3834
<211>  2088
<212>  DNA
<213>  Homo Sapiens

<400>  3834
ggtctcaaca tatgcactag tggaagtgcc acctcatgtg aagaatgtct gctaatccac       60

ccaaaatgtg cctggtgctc caaagaggac ttcggaagcc cacggtccat cacctctcgg      120

tgtgatctga gggcaaacct tgtcaaaaat ggctgtggag gtgagataga gagcccagcc      180

agcagcttcc atgtcctgag gagcctgccc ctcagcagca agggttcggg ctctgcaggc      240

tgggacgtca ttcagatgac accacaggag attgccgtga acctccggcc cggtgacaag      300

accaccttcc agctacaggt tcgccaggtg gaggactatc ctgtggacct gtactacctg      360

atggacctct ccctgtccat gaaggatgac ttggacaata tccggagcct gggcaccaaa      420

ctcgcggagg agatgaggaa gctcaccagc aacttccggt tgggatttgg gtcttttgtt      480

gataaggaca tctctccttt ctcctacacg gcaccgaggt accagaccaa tccgtgcatt      540

ggttacaagt tgtttccaaa ttgcgtcccc tcctttgggt tccgccatct gctgcctctc      600

acagacagag tggacagctt caatgaggaa gttcggaaac agagggtgtc ccggaaccga      660

gatgcccctg aggggggctt tgatgcagta ctccaggcag ccgtctgcaa ggagaagatt      720

ggctggcgaa aggatgcact gcatttgctg gtgttcacaa cagatgatgt gccccacatc      780

gcattggatg gaaaattggg aggcctggtg cagccacacg atggccagtg ccacctgaac      840

gaggccaacg agtacactgc atccaaccag atggactatc catcccttgc cttgcttgga      900

gagaaattgg cagagaacaa catcaacctc atctttgcag tgacaaaaaa ccattatatg      960

ctgtacaaga attttacagc cctgatacct ggaacaacgg tggagatttt agatggagac     1020

tccaaaaata ttattcaact gattattaat gcatacaata gtatccggtc taaagtggag     1080

ttgtcagtct gggatcagcc tgaggatctt aatctcttct ttactgctac ctgccaagat     1140

ggggtatcct atcctggtca gaggaagtgt gagggtctga agattgggga cacggcatct     1200

tttgaagtat cattggaggc ccgaagctgt cccagcagac acacggagca tgtgtttgcc     1260

ctgcggccgg tgggattccg ggacagcctg gaggtggggg tcacctacaa ctgcacgtgc     1320

ggctgcagcg tggggctgga acccaacagt gccaggtgca acgggagcgg gacctatgtc     1380

tgcggcctgt gtgagtgcag ccccggctac ctgggcacca ggtgcgagtg ccaggatggg     1440

gagaaccaga gcgtgtacca gaacctgtgc cgggaggcag agggcaagcc actgtgcagc     1500

gggcgtgggg actgcagctg caaccagtgc tcctgcttcg agagcgagtt cggcaagatc     1560

tatgggcctt tctgtgagtg cgacaacttc tcctgtgcca ggaacaaggg agtcctctgc     1620

tcaggccatg gcgagtgtca ctgcggggaa tgcaagtgcc atgcaggtta catcggggac     1680

aactgtaact gctcgacaga catcagcaca tgccggggca gagatggcca gatctgcagc     1740

gagcgtgggc actgtctctg tgggcagtgc caatgcacgg agccgggggc ctttggggag     1800

atgtgtgaga agtgccccac ctgcccggat gcatgcagca ccaagagaga ttgcgtcgag     1860

tgcctgctgc tccactctgg gaaacctgac aaccagacct gccacagcct atgcagggat     1920

gaggtgatca catgggtgga caccatcgtg aaagatgacc aggaggctgt gctatgtttc     1980

tacaaaaccg ccaaggactg cgtcatgatg ttcacctatg tggagctccc cagtgggaag     2040

tccaacctga ccgtcctcag ggagccagag tgtggaaaca cccccaac                  2088


<210>  3835
<211>  2064
<212>  DNA
<213>  Homo Sapiens

<400>  3835
ggctgtgccc tgggaggtgc agaaacctgt gaagactgcc tgcttattgg acctcagtgt       60

gcctggtgtg ctcaggagaa ttttactcat ccatctggag ttggcgaaag gtgtgatacc      120

ccagcaaacc ttttagctaa aggatgtcaa ttaaacttca tcgaaaaccc tgtctcccaa      180

gtagaaatac ttaaaaataa gcctctcagt gtaggcagac agaaaaatag ttctgacatt      240

gttcagattg cgcctcaaag cttgatcctt aagttgagac caggtggtgc gcagactctg      300

caggtgcatg tccgccagac tgaggactac ccggtggatt tgtattacct catggacctc      360

tccgcctcca tggatgacga cctcaacaca ataaaggagc tgggctcccg gctttccaaa      420

gagatgtcta aattaaccag caactttaga ctgggcttcg gatcttttgt ggaaaaacct      480

gtatcccctt ttgtgaaaac aacaccagaa gaaattgcca acccttgcag tagtattcca      540

tacttctgtt tacctacatt tggattcaag cacattttgc cattgacaaa tgatgctgaa      600

agattcaatg aaattgtgaa gaatcagaaa atttctgcta atattgacac acccgaaggt      660

ggatttgatg caattatgca agctgctgtg tgtaaggaaa aaattggctg gcggaatgac      720

tccctccacc tcctggtctt tgtgagtgat gctgattctc attttggaat ggacagcaaa      780

ctagcaggca tcgtcattcc taatgacggg ctctgtcact tggacagcaa gaatgaatac      840

tccatgtcaa ctgtcttgga atatccaaca attggacaac tcattgataa actggtacaa      900

aacaacgtgt tattgatctt cgctgtaacc caagaacaag ttcatttata tgagaattac      960

gcaaaactta ttcctggagc tacagtaggt ctacttcaga aggactccgg aaacattctc     1020

cagctgatca tctcagctta tgaagaactg cggtctgagg tggaactgga agtattagga     1080

gacaccgaag gactcaactt gtcatttaca gccatctgta acaacggtac cctcttccaa     1140

caccaaaaga aatgctctca catgaaagtg ggagacacag cttccttcag cgtgactgtg     1200

aatatcccac actgcgagag aagaagcagg cacattatca taaagcctgt ggggctgggg     1260

gatgccctgg aattacttgt cagcccagaa tgcaactgcg actgtcagaa agaagtggaa     1320

gtgaacagcc ccaaatgtca ccacgggaac ggctctttcc agtgtggggc gtgtgcctgc     1380

caccctggcc acatggggcc tcgctgtgag tgtggcgagg acatgctgag cacagattcc     1440

tgcaaggagg ccccagatca tccctcctgc agcggaaggg gtgactgcta ctgtgggcag     1500

tgtatctgcc acttgtctcc ctatggaaac atttatgggc cttattgcca gtgtgacaat     1560

ttctcctgcg tgagacacaa agggctgctc tgcggaggta acggcgactg tgactgtggt     1620

gaatgtgtgt gcaggagcgg ctggactggc gagtactgca actgcaccac cagcacggac     1680

tcctgcgtct ctgaagatgg agtgctctgc agcgggcgcg gggactgtgt ttgtggcaag     1740

tgtgtttgca caaaccctgg ggcctcagga ccaacctgtg aacgatgtcc tacctgtggt     1800

gacccctgta actctaaacg gagctgcatt gagtgccacc tgtcagcagc tggccaagcc     1860

cgagaagaat gtgtggacaa gtgcaaacta gctggtgcga ccatcagtga agaagaagat     1920

ttctcaaagg atggttctgt ttcctgctct ctgcaaggag aaaatgaatg tcttattaca     1980

ttcctaataa ctacagataa tgaggggaaa accatcattc acagcatcaa tgaaaaagat     2040

tgtccgaagc ctccaaacat tccc                                            2064


<210>  3836
<211>  2112
<212>  DNA
<213>  Homo Sapiens

<400>  3836
gaattggacg ccaagatccc atccacaggg gatgccacag aatggcggaa tcctcacctg       60

tccatgctgg ggtcctgcca gccagccccc tcctgccaga agtgcatcct ctcacacccc      120

agctgtgcat ggtgcaagca actgaacttc accgcgtcgg gagaggcgga ggcgcggcgc      180

tgcgcccgac gagaggagct gctggctcga ggctgcccgc tggaggagct ggaggagccc      240

cgcggccagc aggaggtgct gcaggaccag ccgctcagcc agggcgcccg cggagagggt      300

gccacccagc tggcgccgca gcgggtccgg gtcacgctgc ggcctgggga gccccagcag      360

ctccaggtcc gcttccttcg tgctgaggga tacccggtgg acctgtacta ccttatggac      420

ctgagctact ccatgaagga cgacctggaa cgcgtgcgcc agctcgggca cgctctgctg      480

gtccggctgc aggaagtcac ccattctgtg cgcattggtt ttggttcctt tgtggacaaa      540

acggtgctgc cctttgtgag cacagtaccc tccaaactgc gccacccctg ccccacccgg      600

ctggagcgct gccagtcacc attcagcttt caccatgtgc tgtccctgac gggggacgca      660

caagccttcg agcgggaggt ggggcgccag agtgtgtccg gcaatctgga ctcgcctgaa      720

ggtggcttcg atgccattct gcaggctgca ctctgccagg agcagattgg ctggagaaat      780

gtgtcccggc tgctggtgtt cacttcagac gacacattcc atacagctgg ggacgggaag      840

ttgggcggca ttttcatgcc cagtgatggg cactgccact tggacagcaa tggcctctac      900

agtcgcagca cagagtttga ctacccttct gtgggtcagg tagcccaggc cctctctgca      960

gcaaatatcc agcccatctt tgctgtcacc agtgccgcac tgcctgtcta ccaggagctg     1020

agtaaactga ttcctaagtc tgcagttggg gagctgagtg aggactccag caacgtggta     1080

cagctcatca tggatgctta taatagcctg tcttccaccg tgacccttga acactcttca     1140

ctccctcctg gggtccacat ttcttacgaa tcccagtgtg agggtcctga gaagagggag     1200

ggtaaggctg aggatcgagg acagtgcaac cacgtccgaa tcaaccagac ggtgactttc     1260

tgggtttctc tccaagccac ccactgcctc ccagagcccc atctcctgag gctccgggcc     1320

cttggcttct cagaggagct gattgtggag ttgcacacgc tgtgtgactg taattgcagt     1380

gacacccagc cccaggctcc ccactgcagt gatggccagg gacacctaca atgtggtgta     1440

tgcagctgtg cccctggccg cctaggtcgg ctctgtgagt gctctgtggc agagctgtcc     1500

tccccagacc tggaatctgg gtgccgggct cccaatggca cagggcccct gtgcagtgga     1560

aagggtcact gtcaatgtgg acgctgcagc tgcagtggac agagctctgg gcatctgtgc     1620

gagtgtgacg atgccagctg tgagcgacat gagggcatcc tctgcggagg ctttggtcgc     1680

tgccaatgtg gagtatgtca ctgtcatgcc aaccgcacgg gcagagcatg cgaatgcagt     1740

ggggacatgg acagttgcat cagtcccgag ggagggctct gcagtgggca tggacgctgc     1800

aaatgcaacc gctgccagtg cttggacggc tactatggtg ctctatgcga ccaatgccca     1860

ggctgcaaga caccatgcga gagacaccgg gactgtgcag agtgtggggc cttcaggact     1920

ggcccactgg ccaccaactg cagtacagct tgtgcccata ccaatgtgac cctggccttg     1980

gcccctatct tggatgatgg ctggtgcaaa gagcggaccc tggacaacca gctgttcttc     2040

ttcttggtgg aggatgacgc cagaggcacg gtcgtgctca gagtgagacc ccaagaaaag     2100

ggagcagacc ac                                                         2112


<210>  3837
<211>  1191
<212>  DNA
<213>  Homo Sapiens

<400>  3837
gaagacaata gatgtgcatc ttcaaatgca gcatcctgtg ccaggtgcct tgcgctgggt       60

ccagaatgtg gatggtgtgt tcaagaggat ttcatttcag gtggatcaag aagtgaacgt      120

tgtgatattg tttccaattt aataagcaaa ggctgctcag ttgattcaat agaataccca      180

tctgtgcatg ttataatacc cactgaaaat gaaattaata cccaggtgac accaggagaa      240

gtgtctatcc agctgcgtcc aggagccgaa gctaatttta tgctgaaagt tcatcctctg      300

aagaaatatc ctgtggatct ttattatctt gttgatgtct cagcatcaat gcacaataat      360

atagaaaaat taaattccgt tggaaacgat ttatctagaa aaatggcatt tttctcccgt      420

gactttcgtc ttggatttgg ctcatacgtt gataaaacag tttcaccata cattagcatc      480

caccccgaaa ggattcataa tcaatgcagt gactacaatt tagactgcat gcctccccat      540

ggatacatcc atgtgctgtc tttgacagag aacatcactg agtttgagaa agcagttcat      600

agacagaaga tctctggaaa catagataca ccagaaggag gttttgacgc catgcttcag      660

gcagctgtct gtgaaagtca tatcggatgg cgaaaagagg ctaaaagatt gctgctggtg      720

atgacagatc agacgtctca tctcgctctt gatagcaaat tggcaggcat agtggtgccc      780

aatgacggaa actgtcatct gaaaaacaac gtctatgtca aatcgacaac catggaacac      840

ccctcactag gccaactttc agagaaatta atagacaaca acattaatgt catctttgca      900

gttcaaggaa aacaatttca ttggtataag gatcttctac ccctcttgcc aggcaccatt      960

gctggtgaaa tagaatcaaa ggctgcaaac ctcaataatt tggtagtgga agcctatcag     1020

aagctcattt cagaagtgaa agttcaggtg gaaaaccagg tacaaggcat ctattttaac     1080

attaccgcca tctgtccaga tgggtccaga aagccaggca tggaaggatg cagaaacgtg     1140

acgagcaatg atgaagtatg tgggtgtgca tttttccctt ttaaaataaa c              1191


<210>  3838
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  3838
gttcctcaaa gcttctcgcc atctctgagg agctggccgg gcgccgcctg caggctgtcc       60

cgggccgagt cggagcgacg ctgccgcgca cctgggcagc ccccgggggc cgcgctgtgc      120

cacggccggg gccgctgcga ctgcggcgtc tgcatctgcc acgtgactga gccgggcatg      180

ttcttcgggc ccctgtgtga gtgccatgag tgggtgtgcg agacctacga cgggagcacc      240

tgtgcaggcc atggtaagtg tgactgtggc aagtgcaagt gtgaccaggg atggtatggg      300

gatgcttgcc agtacccaac taactgtgac ttgacaaaga agaaaagtaa ccaaatgtgc      360

aagaattcac aagacatcat ctgctctaat gcaggtacat gtcactgtgg caggtgtaag      420

tgtgataatt cagatggaag tggacttgtg tatggtaaat tttgtgagtg tgacgataga      480

gaatgcatag acgatgaaac agaagaaata tgtggaggcc atgggaagtg ttactgtgga      540

aactgctact gcaaggctgg ttggcatgga gataaatgtg aattccagtg cgatatcacc      600

ccctgggaaa gcaagcgaag atgcacgtct ccagatggca aaatctgcag taacagaggg      660

acttgtgtat gtggtgaatg tacctgtcac gatgttgatc cgactgggga ctggggagat      720

attcatgggg acacctgtga atgtgatgag agggactgta gagctgtcta tgaccgatat      780

tctgatgact tctgttcagg tcatggacag tgtaattgcg gaagatgtga ctgcaaagca      840

ggctggtatg ggaagaagtg tgagcaccca cagtcctgca cgctgtcagc tgaggagagc      900

atcaggaagt gccagggaag ctcggatctg ccttgctctg ggaggggtaa atgtgaatgt      960

ggcaaatgca cctgctatcc tccaggagat cgccgggtgt atggcaagac ttgtgagtgt     1020

gatgatcgcc gctgtgaaga cctcgatggt gtggtctgtg gaggccacgg cacatgttcc     1080

tgtggtcgct gtgtttgtga gagaggatgg tttggaaagc tctgccaaca tccgcggaag     1140

tgtaacatga cggaagaaca aagcaagaat ctgtgtgaat cagcagatgg catattgtgc     1200

tcggggaagg gttcttgtca ttgtgggaag tgcatttgtt ctgctgaaga gtggtatatt     1260

tctggggagt tctgtgactg tgatgacaga gactgcgaca aacatgatgg tctcatttgt     1320

acagggaatg gaatatgtag ctgtggaaac tgtgaatgct gggatggatg gaatggaaat     1380

gcatgtgaaa tctggcttgg ctcagaatat cct                                  1413


<210>  3839
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  3839
tgtgttatat gtgacccgtc tgtcgtgctg gcgctaaagt ccctggagaa agattacctg       60

cctggccacc tggatgcgaa gcatcacaaa gccatgatgg aaagggtaga gaatgccgtg      120

aaggatttcc aggaactgtc gcttaatgag gatgcctata tgggggtcgt tgatgaggcc      180

acactgcaaa aggggtcctg gagtttgctg aaggatctga aacgcatcac agacagtgat      240

gtaaaaggcg atctctttgt gaaggagcta ttttggatgt tgcacttgca aaaggaaacc      300

tttgccacct atgttgctcg attccaaaaa gaggcttatt gtcccaacaa atgtggtgtg      360

atgttgcaaa ctctgatctg gtgcaagaac tgcaaaaagg aggttcacgc ttgtcgaaag      420

tcctacgatt gcggggagcg gaatgtggaa gttcctcaaa tggaagacat gatcctggac      480

tgtgagttaa actggcatca ggcttcggaa ggcctcactg attacagctt ttacagggtt      540

tgggggaaca atacggagac cttggtgtcc aaggggaaag aggccaccct gaccaagccc      600

atggtgggtc cagaggatgc aggcagctac cgctgcgagc tgggctctgt gaattccagc      660

ccagccacga tcatcaattt tcacgtcaca gtgttgccca aaatgatcaa ggaggaaaaa      720

ccttctccaa atatcgtaac cccgggggag gcgaccacgg agtcgtccat aagcctccag      780

cctctgcagc ccgagaaaat gctggcaagc cgc                                   813


<210>  3840
<211>  3102
<212>  DNA
<213>  Homo Sapiens

<400>  3840
cagttcgagt tggagatcct gtccatgcag aacgtgaacg gggagctgca gaacgggaac       60

tgctgcggcg gcgcccggaa cccgggagac cgcaagtgca cccgcgacga gtgtgacaca      120

tacttcaaag tgtgcctcaa ggagtatcag tcccgcgtca cggccggggg gccctgcagc      180

ttcggctcag ggtccacgcc tgtcatcggg ggcaacacct tcaacctcaa ggccagccgc      240

ggcaacgacc gcaaccgcat cgtgctgcct ttcagtttcg cctggccgag gtcctatacg      300

ttgcttgtgg aggcgtggga ttccagtaat gacaccgttc aacctgacag tattattgaa      360

aaggcttctc actcgggcat gatcaacccc agccggcagt ggcagacgct gaagcagaac      420

acgggcgttg cccactttga gtatcagatc cgcgtgacct gtgatgacta ctactatggc      480

tttggctgca ataagttctg ccgccccaga gatgacttct ttggacacta tgcctgtgac      540

cagaatggca acaaaacttg catggaaggc tggatgggcc ccgaatgtaa cagagctatt      600

tgccgacaag gctgcagtcc taagcatggg tcttgcaaac tcccaggtga ctgcaggtgc      660

cagtatggct ggcaaggcct gtactgtgat aagtgcatcc cacacccggg atgcgtccac      720

ggcatctgta atgagccctg gcagtgcctc tgtgagacca actggggcgg ccagctctgt      780

gacaaagatc tcaattactg tgggactcat cagccgtgtc tcaacggggg aacttgtagc      840

aacacaggcc ctgacaaata tcagtgttcc tgccctgagg ggtattcagg acccaactgt      900

gaaattgctg agcacgcctg cctctctgat ccctgtcaca acagaggcag ctgtaaggag      960

acctccctgg gctttgagtg tgagtgttcc ccaggctgga ccggccccac atgctctaca     1020

aacattgatg actgttctcc taataactgt tcccacgggg gcacctgcca ggacctggtt     1080

aacggattta agtgtgtgtg ccccccacag tggactggga aaacgtgcca gttagatgca     1140

aatgaatgtg aggccaaacc ttgtgtaaac gccaaatcct gtaagaatct cattgccagc     1200

tactactgcg actgtcttcc cggctggatg ggtcagaatt gtgacataaa tattaatgac     1260

tgccttggcc agtgtcagaa tgacgcctcc tgtcgggatt tggttaatgg ttatcgctgt     1320

atctgtccac ctggctatgc aggcgatcac tgtgagagag acatcgatga atgtgccagc     1380

aacccctgtt tgaatggggg tcactgtcag aatgaaatca acagattcca gtgtctgtgt     1440

cccactggtt tctctggaaa cctctgtcag ctggacatcg attattgtga gcctaatccc     1500

tgccagaacg gtgcccagtg ctacaaccgt gccagtgact atttctgcaa gtgccccgag     1560

gactatgagg gcaagaactg ctcacacctg aaagaccact gccgcacgac cccctgtgaa     1620

gtgattgaca gctgcacagt ggccatggct tccaacgaca cacctgaagg ggtgcggtat     1680

atttcctcca acgtctgtgg tcctcacggg aagtgcaaga gtcagtcggg aggcaaattc     1740

acctgtgact gtaacaaagg cttcacggga acatactgcc atgaaaatat taatgactgt     1800

gagagcaacc cttgtagaaa cggtggcact tgcatcgatg gtgtcaactc ctacaagtgc     1860

atctgtagtg acggctggga gggggcctac tgtgaaacca atattaatga ctgcagccag     1920

aacccctgcc acaatggggg cacgtgtcgc gacctggtca atgacttcta ctgtgactgt     1980

aaaaatgggt ggaaaggaaa gacctgccac tcacgtgaca gtcagtgtga tgaggccacg     2040

tgcaacaacg gtggcacctg ctatgatgag ggggatgctt ttaagtgcat gtgtcctggc     2100

ggctgggaag gaacaacctg taacatagcc cgaaacagta gctgcctgcc caacccctgc     2160

cataatgggg gcacatgtgt ggtcaacggc gagtccttta cgtgcgtctg caaggaaggc     2220

tgggaggggc ccatctgtgc tcagaatacc aatgactgca gccctcatcc ctgttacaac     2280

agcggcacct gtgtggatgg agacaactgg taccggtgcg aatgtgcccc gggttttgct     2340

gggcccgact gcagaataaa catcaatgaa tgccagtctt caccttgtgc ctttggagcg     2400

acctgtgtgg atgagatcaa tggctaccgg tgtgtctgcc ctccagggca cagtggtgcc     2460

aagtgccagg aagtttcagg gagaccttgc atcaccatgg ggagtgtgat accagatggg     2520

gccaaatggg atgatgactg taatacctgc cagtgcctga atggacggat cgcctgctca     2580

aaggtctggt gtggccctcg accttgcctg ctccacaaag ggcacagcga gtgccccagc     2640

gggcagagct gcatccccat cctggacgac cagtgcttcg tccacccctg cactggtgtg     2700

ggcgagtgtc ggtcttccag tctccagccg gtgaagacaa agtgcacctc tgactcctat     2760

taccaggata actgtgcgaa catcacattt acctttaaca aggagatgat gtcaccaggt     2820

cttactacgg agcacatttg cagtgaattg aggaatttga atattttgaa gaatgtttcc     2880

gctgaatatt caatctacat cgcttgcgag ccttcccctt cagcgaacaa tgaaatacat     2940

gtggccattt ctgctgaaga tatacgggat gatgggaacc cgatcaagga aatcactgac     3000

aaaataatcg atcttgttag taaacgtgat ggaaacagct cgctgattgc tgccgttgca     3060

gaagtaagag ttcagaggcg gcctctgaag aacagaacag at                        3102


<210>  3841
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3841
atgggctatt tcgagctgca gctgagcgcg ctgcggaacg tgaacgggga gctgctgagc       60

ggcgcctgct gtgacggcga cggccggaca acgcgcgcgg ggggctgcgg ccacgacgag      120

tgcgacacgt acgtgcgcgt gtgccttaag gagtaccagg ccaaggtgac gcccacgggg      180

ccctgcagct acggccacgg cgccacgccc gtgctgggcg gcaactcctt ctacctgccg      240

ccggcgggcg ctgcggggga ccgagcgcgg gcgcgggccc gggccggcgg cgaccaggac      300

ccgggcctcg tcgtcatccc cttccagttc gcctggccgc gctcctttac cctcatcgtg      360

gaggcctggg actgggacaa cgataccacc ccgaatgagg agctgctgat cgagcgagtg      420

tcgcatgccg gcatgatcaa cccggaggac cgctggaaga gcctgcactt cagcggccac      480

gtggcgcacc tggagctgca gatccgcgtg cgctgcgacg agaactacta cagcgccact      540

tgcaacaagt tctgccggcc ccgcaacgac tttttcggcc actacacctg cgaccagtac      600

ggcaacaagg cctgcatgga cggctggatg ggcaaggagt gcaaggaagc tgtgtgtaaa      660

caagggtgta atttgctcca cgggggatgc accgtgcctg gggagtgcag gtgcagctac      720

ggctggcaag ggaggttctg cgatgagtgt gtcccctacc ccggctgcgt gcatggcagt      780

tgtgtggagc cctggcagtg caactgtgag accaactggg gcggcctgct ctgtgacaaa      840

gacctgaact actgtggcag ccaccacccc tgcaccaacg gaggcacgtg catcaacgcc      900

gagcctgacc agtaccgctg cacctgccct gacggctact cgggcaggaa ctgtgag         957


<210>  3842
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  3842
ttttctgccc caaaagacca acaagtagtc acagcagtag agtaccaaga ggctatttta       60

gcctgcaaaa ccccaaagaa gactgtttcc tccagattag agtggaagaa actgggtcgg      120

agtgtctcct ttgtctacta tcaacagact cttcaaggtg attttaaaaa tcgagctgag      180

atgatagatt tcaatatccg gatcaaaaat gtgacaagaa gtgatgcggg gaaatatcgt      240

tgtgaagtta gtgccccatc tgagcaaggc caaaacctgg aagaggatac agtcactctg      300

gaagtattag tggctccagc agttccatca tgtgaagtac cctcttctgc tctgagtgga      360

actgtggtag agctacgatg tcaagacaaa gaagggaatc cagctcctga atacacatgg      420

tttaaggatg gcatccgttt gctagaaaat cccagacttg gctcccaaag caccaacagc      480

tcatacacaa tgaatacaaa aactggaact ctgcaattta atactgtttc caaactggac      540

actggagaat attcctgtga agcccgcaat tctgttggat atcgcaggtg tcctgggaaa      600

cgaatgcaag tagatgatct caacataagt                                       630


<210>  3843
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  3843
gtaaatctca aatccagcaa tcgaacccca gtggtacagg aatttgaaag tgtggaactg       60

tcttgcatca ttacggattc gcagacaagt gaccccagga tcgagtggaa gaaaattcaa      120

gatgaacaaa ccacatatgt gttttttgac aacaaaattc agggagactt ggcgggtcgt      180

gcagaaatac tggggaagac atccctgaag atctggaatg tgacacggag agactcagcc      240

ctttatcgct gtgaggtcgt tgctcgaaat gaccgcaagg aaattgatga gattgtgatc      300

gagttaactg tgcaagtgaa gccagtgacc cctgtctgta gagtgccgaa ggctgtacca      360

gtaggcaaga tggcaacact gcactgccag gagagtgagg gccacccccg gcctcactac      420

agctggtatc gcaatgatgt accactgccc acggattcca gagccaatcc cagatttcgc      480

aattcttctt tccacttaaa ctctgaaaca ggcactttgg tgttcactgc tgttcacaag      540

gacgactctg ggcagtacta ctgcattgct tccaatgacg caggctcagc caggtgtgag      600

gagcaggaga tggaagtcta tgacctgaac                                       630


<210>  3844
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  3844
caagaagatg aaaggattgt tcttgttgac aacaaatgta agtgtgcccg gattacttcc       60

aggatcatcc gttcttccga agatcctaat gaggacattg tggagagaaa catccgaatt      120

attgttcctc tgaacaacag ggagaatatc tctgatccca cctcaccatt gagaaccaga      180

tttgtgtacc atttgtctga cctctgtaaa aaatgtgatc ctacagaagt ggagctggat      240

aatcagatag ttactgctac ccagagcaat atctgtgatg aagacagtgc tacagagacc      300

tgctacactt atgacagaaa caagtgctac acagctgtgg tcccactcgt atatggtggt      360

gagaccaaaa tggtggaaac agccttaacc ccagatgcct gctatcctga c               411


<210>  3845
<211>  1968
<212>  DNA
<213>  Homo Sapiens

<400>  3845
gccggccccg gcgcggctgc tgcgcggcgg ctggacgagt cgctgtctgc cgggagcgtc       60

cagcgcgctc gctgcgcctc caggtgcctg agcctgcaga tcactcgcat ctccgccttc      120

ttccagcact tccagaacaa tggttccctg gtttggtgcc agaatcacaa gcaatgttct      180

aagtgcctgg agccctgcaa ggaatcaggg gacctgagga aacaccagtg ccaaagcttt      240

tgtgagcctc tcttccccaa gaagagctac gaatgcttga ccagctgtga gttcctcaaa      300

tacatcctgt tggtgaagca gggggactgt ccggctcctg agaaagccag tggatttgcg      360

gccgcctgtg ttgaaagctg cgaagttgac aatgagtgct ctggggtgaa gaaatgttgt      420

tcgaatgggt gtggacacac ctgtcaagta cccaagactc tgtacaaagg tgtccccctg      480

aagcccagaa aagagttacg atttacagaa ctgcagtctg gacagctgga ggttaagtgg      540

tcctcgaaat tcaatatttc tattgagcct gtgatctatg tggtacaaag aagatggaat      600

tatggaatcc atcctagcga agatgacgcc actcactggc agacagtggc ccagaccaca      660

gacgagcgag ttcaactgac tgacataaga cccagccgat ggtaccagtt tcgagtggct      720

gctgtgaatg tgcatggaac tcgaggcttc actgccccca gcaaacactt ccgttcttcc      780

aaagatccat ctgccccacc agcaccggct aacctccggc tggccaactc caccgtcaac      840

agtgatggga gtgtgaccgt cactatagtt tgggatctcc ccgaggagcc ggacatccct      900

gtgcatcatt acaaggtctt ttggagctgg atggtcagca gtaagtctct tgtcccaaca      960

aagaagaagc ggagaaagac tacggatggg tttcaaaatt ctgtgatcct ggagaaactc     1020

cagccagact gtgactatgt tgtggaattg caagccataa cgtactgggg acagacacgg     1080

ctgaagagtg caaaggtgtc ccttcacttc acatcgacac atgcaaccaa caacaaagaa     1140

cagcttgtga aaactagaaa aggtggaatt caaacacaac tcccttttca aagacgacga     1200

cccactcgcc cgctggaagt cggagctccc ttctatcagg atggccaact gcaagttaaa     1260

gtctactgga agaagacaga agatcccact gtcaaccgat atcatgtgcg gtggtttcct     1320

gaagcgtgtg cccacaacag aacaaccgga tcagaggcat catctggcat gacccacgaa     1380

aattacataa ttcttcaaga tctgtcattt tcctgcaagt ataaggtgac tgtccaacca     1440

atacggccaa aaagtcactc caaggcagaa gctgttttct tcactactcc accatgctct     1500

gctcttaagg ggaagagcca caagcctatt ggctgcctgg gcgaagcagg tcatgttctt     1560

tctaaggtgc tagctaagcc tgagaacctt tctgcttcat tcatcgtcca ggatgtgaac     1620

atcaccggtc acttttcttg gaagatggcc aaggccaatc tctatcagcc catgactggg     1680

tttcaagtga cttgggctga ggtcactacg gaaagcagac agaacagcct acccaacagc     1740

attatttcac agtcccagat tctgccttcc gatcattatg tcctaacagt gcccaatctg     1800

agaccatcta ctctttaccg actggaagtg caagtgctga ccccaggagg ggaggggccg     1860

gccaccatca agacgttccg gacgccggag ctcccaccct cttcagcaca cagatctcat     1920

cttaagcatc gtcatccaca tcattacaag ccttctccag aaagatac                  1968


<210>  3846
<211>  822
<212>  DNA
<213>  Homo Sapiens

<400>  3846
aggccatccc caggcccaga ttacctgcgg cgcggctgga tgcggctgct agcggagggc       60

gagggctgcg ctccctgccg gccagaagag tgcgccgcgc cgcggggctg cctggcgggc      120

agggtgcgcg acgcgtgcgg ctgctgctgg gaatgcgcca acctcgaggg ccagctctgc      180

gacctggacc ccagtgctca cttctacggg cactgcggcg agcagcttga gtgccggctg      240

gacacaggcg gcgacctgag ccgcggagag gtgccggaac ctctgtgtgc ctgtcgttcg      300

cagagtccgc tctgcgggtc cgacggtcac acctactccc agatctgccg cctgcaggag      360

gcggcccgcg ctcggcccga tgccaacctc actgtggcac acccggggcc ctgcgaatcg      420

gggccccaga tcgtgtcaca tccatatgac acttggaatg tgacagggca ggatgtgatc      480

tttggctgtg aagtgtttgc ctaccccatg gcctccatcg agtggaggaa ggatggcttg      540

gacatccagc tgccagggga tgacccccac atctctgtgc agtttagggg tggaccccag      600

aggtttgagg tgactggctg gctgcagatc caggctgtgc gtcccagtga tgagggcact      660

taccgctgcc ttggccgcaa tgccctgggt caagtggagg cccctgctag cttgacagtg      720

ctcacacctg accagctgaa ctctacaggc atcccccagc tgcgatcact aaacctggtt      780

cctgaggagg aggctgagag tgaagagaat gacgattact ac                         822


<210>  3847
<211>  1449
<212>  DNA
<213>  Homo Sapiens

<400>  3847
gagaccggcg gagaaaggca gctgagcccg gagaagagcg aaatatgggg acccgggcta       60

aaagcagacg tcgtccttcc cgcccgctat ttctatattc aggcagtgga tacatcaggg      120

aataaattca catcttctcc aggcgaaaag gtcttccagg tgaaagtctc agcaccagag      180

gagcaattca ctagagttgg agtccaggtt ttagaccgaa aagatgggtc cttcatagta      240

agatacagaa tgtatgcaag ctacaaaaat ctgaaggtgg aagttaaatt ccaagggcaa      300

catgtggcca aatccccata tattttaaaa gggccggttt accatgagaa ctgtgactgt      360

cctctgcaag atagtgcagc ctggctacgg gagatgaact gccctgaaac cattgctcag      420

attcagagag atctggcaca tttccctgct gtggatccag aaaagattgc agtagaaatc      480

ccaaaaagat ttggacagag gcagagccta tgtcactaca ccttaaagga taacaaggtt      540

tatatcaaga ctcatggtga acatgtaggt tttagaattt tcatggatgc catactactt      600

tctttgacta gaaaggtgaa gatgccagat gtggagctct ttgttaattt gggagactgg      660

cctttggaaa aaaagaaatc caattcaaac atccatccga tcttttcctg gtgtggctcc      720

acagattcca aggatatcgt gatgcctacg tacgatttga ctgattctgt tctggaaacc      780

atgggccggg taagtctgga tatgatgtcc gtgcaagcta acacgggtcc tccctgggaa      840

agcaaaaatt ccactgccgt ctggagaggg cgagacagcc gcaaagagag actcgagctg      900

gttaaactca gtagaaaaca cccagaactc atagacgctg ctttcaccaa ctttttcttc      960

tttaaacacg atgaaaacct gtatggtccc attgtgaaac atatttcatt ttttgatttc     1020

ttcaagcata agtatcaaat aaatatcgat ggcactgtag cagcttatcg cctgccatat     1080

ttgctagttg gtgacagtgt tgtgctgaag caggattcca tctactatga acatttttac     1140

aatgagctgc agccctggaa acactacatt ccagttaaga gcaacctgag cgatctgcta     1200

gaaaaactta aatgggcgaa agatcacgat gaagaggcca aaaagatagc aaaagcagga     1260

caagaatttg caagaaataa tctcatgggc gatgacatat tctgttatta tttcaaactt     1320

ttccaggaat atgccaattt acaagtgagt gagccccaaa tccgagaggg catgaaaagg     1380

gtagaaccac agactgagga cgacctcttc ccttgtactt gccataggaa aaagaccaaa     1440

gatgaactc                                                             1449


<210>  3848
<211>  1461
<212>  DNA
<213>  Homo Sapiens

<400>  3848
ggggccccgg aggtgctggt cagcgcgccg cggagcctgg tgtgggggcc cgggctgcag       60

gcggccgtcg tcctgccggt ccgctatttc tacctgcagg cggtcaactc ggagggccag      120

aacctcactc gctctcccgc aggtgaaaca ccattcaaag tcgtagtcaa atctctttca      180

cctaaagagt tggtccggat acatgtccct aaacctttgg acaggaatga tggaacattt      240

ttgatgagat ataggatgta tgaaactgtc gatgaaggcc tgaagataga ggtcctttat      300

ggtgatgaac atgtggctca gtctccctat attttgaaag gaccagtgta ccatgagtac      360

tgtgagtgtc cggaagatcc tcaggcctgg cagaagactc tttcttgtcc aaccaaggaa      420

ccacagattg caaaagattt tgcttccttt cccagcatca atctccagca aatgctaaaa      480

gaagtcccca aaaggtttgg ggatgagaga ggtgccattg ttcattacac gattctcaat      540

aaccatgttt accggagatc tttagggaaa tacacagact tcaagatgtt ctctgatgag      600

attttgttat cattgacaag aaaggtcctt ctcccagatt tagaatttta tgttaatctt      660

ggagattggc ccttggagca tcgaaaagtc aatggaaccc ctagccccat acctatcatt      720

tcatggtgtg gctctctgga ttcaagagat gttgtccttc caacgtatga catcacccac      780

tccatgcttg aagccatgcg gggtgttaca aatgatctcc tctctattca gggaaataca      840

gggccttcct ggatcaataa aacagagaga gctttcttca gaggtagaga cagcctagag      900

gagaggctcc agttggtaca gctgtccaaa gaaaatcctc agctactaga tgcaggaatt      960

acaggatatt tctttttcca agagaaagaa aaggagcttg gaaaagccaa gttgatgggt     1020

ttctttgatt tctttaagta caagtatcaa gtaaatgtgg atgggaccgt ggctgcttac     1080

agatatccat atctcatgct gggcgacagt ctggttttaa agcaggactc gccatattat     1140

gaacatttct acatggcact agaaccttgg aagcattatg ttccaattaa aagaaatctg     1200

agtgatttat tagagaaagt taaatgggct aaggaaaatg atgaagaagc caagaagatt     1260

gcaaaagaag gacagttgat ggctagggac ctactacagc cacacaggct ttactgctac     1320

tattaccaag tactgcagaa atatgccgag cgccagtcca gcaaacccga agtacgtgat     1380

ggaatggaac ttgttcctca gccagaagat agcacagcca tctgccagtg ccacaggaaa     1440

aagccttcaa gagaagaact t                                               1461


<210>  3849
<211>  2235
<212>  DNA
<213>  Homo Sapiens

<400>  3849
gcctctgtgg gtttgcctag tgtttctctt gatctgccca ggctcagcat acaaaaagac       60

atacttacaa ttaaggctaa tacaactctt caaattactt gcaggggaca gagggacttg      120

gactggcttt ggcccaataa tcagagtggc agtgagcaaa gggtggaggt gactgagtgc      180

agcgatggcc tcttctgtaa gacactcaca attccaaaag tgatcggaaa tgacactgga      240

gcctacaagt gcttctaccg ggaaactgac ttggcctcgg tcatttatgt ctatgttcaa      300

gattacagat ctccatttat tgcttctgtt agtgaccaac atggagtcgt gtacattact      360

gagaacaaaa acaaaactgt ggtgattcca tgtctcgggt ccatttcaaa tctcaacgtg      420

tcactttgtg caagataccc agaaaagaga tttgttcctg atggtaacag aatttcctgg      480

gacagcaaga agggctttac tattcccagc tacatgatca gctatgctgg catggtcttc      540

tgtgaagcaa aaattaatga tgaaagttac cagtctatta tgtacatagt tgtcgttgta      600

gggtatagga tttatgatgt ggttctgagt ccgtctcatg gaattgaact atctgttgga      660

gaaaagcttg tcttaaattg tacagcaaga actgaactaa atgtggggat tgacttcaac      720

tgggaatacc cttcttcgaa gcatcagcat aagaaacttg taaaccgaga cctaaaaacc      780

cagtctggga gtgagatgaa gaaatttttg agcaccttaa ctatagatgg tataacccgg      840

agtgaccaag gattgtacac ctgtgcagca tccagtgggc tgatgaccaa gaagaacagc      900

acatttgtca gggtccatga aaaacctttt gttgcttttg gaagtggcat ggaatctctg      960

gtggaagcca cggtggggga gcgtgtcaga atccctgcga agtaccttgg ttacccaccc     1020

ccagaaataa aatggtataa aaatggaata ccccttgagt ccaatcacac aattaaagcg     1080

gggcatgtac tgacgattat ggaagtgagt gaaagagaca caggaaatta cactgtcatc     1140

cttaccaatc ccatttcaaa ggagaagcag agccatgtgg tctctctggt tgtgtatgtc     1200

ccaccccaga ttggtgagaa atctctaatc tctcctgtgg attcctacca gtacggcacc     1260

actcaaacgc tgacatgtac ggtctatgcc attcctcccc cgcatcacat ccactggtat     1320

tggcagttgg aggaagagtg cgccaacgag cccagccatg ctgtctcagt gacaaaccca     1380

tacccttgtg aagaatggag aagtgtggag gacttccagg gaggaaataa aattgaagtt     1440

aataaaaatc aatttgctct aattgaagga aaaaacaaaa ctgtaagtac ccttgttatc     1500

caagcggcaa atgtgtcagc tttgtacaaa tgtgaagcgg tcaacaaagt cgggagagga     1560

gagagggtga tctccttcca cgtgaccagg ggtcctgaaa ttactttgca acctgacatg     1620

cagcccactg agcaggagag cgtgtctttg tggtgcactg cagacagatc tacgtttgag     1680

aacctcacat ggtacaagct tggcccacag cctctgccaa tccatgtggg agagttgccc     1740

acacctgttt gcaagaactt ggatactctt tggaaattga atgccaccat gttctctaat     1800

agcacaaatg acattttgat catggagctt aagaatgcat ccttgcagga ccaaggagac     1860

tatgtctgcc ttgctcaaga caggaagacc aagaaaagac attgcgtggt caggcagctc     1920

acagtcctag agcgtgtggc acccacgatc acaggaaacc tggagaatca gacgacaagt     1980

attggggaaa gcatcgaagt ctcatgcacg gcatctggga atccccctcc acagatcatg     2040

tggtttaaag ataatgagac ccttgtagaa gactcaggca ttgtattgaa ggatgggaac     2100

cggaacctca ctatccgcag agtgaggaag gaggacgaag gcctctacac ctgccaggca     2160

tgcagtgttc ttggctgtgc aaaagtggag gcatttttca taatagaagg tgcccaggaa     2220

aagacgaact tggaa                                                      2235


<210>  3850
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  3850
agaagtgtaa ggcaggtcta tgaagtacat gattcagatg attggactat tcatgacttc       60

gagtgtccca tggaatgttt ctgcccaccc agttttccta ctgctttata ttgtgaaaat      120

agaggtctca aagaaattcc tgctattcct tcaagaattt ggtatcttta tcttcaaaac      180

aacctgatag aaaccattcc tgaaaagcca tttgagaatg ccacccagct aagatggata      240

aatctaaaca agaacaaaat aaccaactac ggaattgaaa aaggagccct aagccagctg      300

aagaagttgc tcttcttatt tctggaagat aatgagctag aggaggtacc ttctccattg      360

ccaagaagtt tagaacaatt acaattagct agaaataagg tgtccagaat tcctcaaggg      420

acctttagca atctggagaa cctgaccctt cttgacctac agaacaacaa attagtggac      480

aatgcctttc aaagagacac ttttaaagga ctcaagaatc tcatgcagct aaacatggcc      540

aagaatgccc tgaggaatat gcctccaaga ttaccagcca atacaatgca gttgttttta      600

gacaacaatt ccattgaagg aataccagaa aattatttta atgtgattcc taaagtggcc      660

tttttgagac taaatcacaa caaactgtca gatgagggtc tcccatcaag aggatttgat      720

gtatcatcaa ttctagatct tcaactgtcg cacaatcaac tcacaaaggt tccccgaatc      780

agtgctcatc tgcagcacct tcaccttgat cataacaaaa ttaaaagtgt gaatgtctct      840

gtaatatgtc ccagcccatc catgctgcct gcagaacgag attccttcag ttatggacct      900

catcttcgct acctccgtct ggatggaaat gaaatcaaac caccaattcc aatggcttta      960

atgacctgct tcagacttct gcaggctgtc attatt                                996


<210>  3851
<211>  2805
<212>  DNA
<213>  Homo Sapiens

<400>  3851
gcccgtaagc agtgcagcga ggggaggaca tattccaatg cagtcatttc acctaacttg       60

gaaaccacca gaatcatgcg ggtgtctcac accttccctg tcgtagactg cacggccgct      120

tgctgtgacc tgtccagctg tgacctggcc tggtggttcg agggccgctg ctacctggtg      180

agctgccccc acaaagagaa ctgtgagccc aagaagatgg gccccatcag gtcttatctc      240

acttttgtgc tccggcctgt tcagaggcct gcacagctgc tggactatgg ggacatgatg      300

ctgaacaggg gctccccctc ggggatctgg ggggactcac ctgaggatat cagaaaggac      360

ttgccctttc taggcaaaga ttggggccta gaggagatgt ctgagtactc agatgactac      420

cgggagctgg agaaggacct cttgcaaccc agtggcaagc aggagcccag agggagtgcc      480

gagtacacgg actggggcct actgccgggc agcgaggggg ccttcaactc ctctgttgga      540

gacagtcctg cggtgccagc ggagacgcag caggaccctg agctccatta cctgaatgag      600

tcggcttcaa cccctgcccc aaaactccct gagagaagtg tgttgcttcc cttgccgact      660

actccatctt caggagaggt gttggagaaa gaaaaggctt ctcagctcca ggaacaatcc      720

agcaacagct ctggaaaaga ggttctaatg ccttcccata gtcttcctcc ggcaagcctg      780

gagctcagct cagtcaccgt ggagaaaagc ccagtgctca cagtcacccc ggggagtaca      840

gagcacagca tcccaacacc tcccactagc gcagccccct ctgagtccac cccatctgag      900

ctacccatat ctcctaccac tgctcccagg acagtgaaag aacttacggt atcggctgga      960

gataacctaa ttataacttt acccgacaat gaagttgaac tgaaggcctt tgttgcgcca     1020

gcgccacctg tagaaacaac ctacaactat gaatggaatt taataagcca ccccacagac     1080

taccaaggtg aaataaaaca aggacacaag caaactctta acctctctca attgtccgtc     1140

ggactttatg tcttcaaagt cactgtttct agtgaaaacg cctttggaga aggatttgtc     1200

aatgtcactg ttaagcctgc cagaagagtc aacctgccac ctgtagcagt tgtttctccc     1260

caactgcaag agctcacttt gcctttgacg tcagccctca ttgatggcag ccaaagtaca     1320

gatgatactg aaatagtgag ttatcattgg gaagaaataa acgggccctt catagaagag     1380

aagacttcag ttgactctcc cgtcttacgc ttgtctaacc ttgatcctgg taactatagt     1440

ttcaggttga ctgttacaga ctcggacgga gccactaact ctacaactgc agccctaata     1500

gtgaacaatg ctgtggacta cccaccagtt gctaatgcag gaccaaatca caccataact     1560

ttgccccaaa actccatcac tttgaatgga aaccagagca gtgacgatca ccagattgtc     1620

ctctatgagt ggtccctggg tcctgggagt gagggcaaac atgtggtcat gcagggagta     1680

cagacgccat accttcattt atctgcaatg caggaaggag attatacatt tcagctgaag     1740

gtgacagatt cttcaaggca acagtctact gctgtggtga ctgtgattgt ccagcctgaa     1800

aacaatagac ctccagtggc tgtggccggc cctgataaag agctgatctt cccagtggaa     1860

agtgctaccc tggatgggag cagcagcagc gatgaccacg gcattgtctt ctaccactgg     1920

gagcacgtca gaggccccag tgcagtggag atggaaaata ttgacaaagc aatagccact     1980

gtgactggtc tccaggtggg gacctaccac ttccgtttga cagtgaaaga ccagcaggga     2040

ctgagcagca cgtccaccct cactgtggct gtgaagaagg aaaataatag tcctcccaga     2100

gcccgggctg gtggcagaca tgttcttgtg cttcccaata attccattac tttggatggt     2160

tcaaggtcta ctgatgacca aagaattgtg tcctatctgt ggatccggga tggccagagt     2220

ccagcagctg gagatgtcat cgatggctct gaccacagtg tggctctgca gcttacgaat     2280

ctggtggagg gggtgtacac tttccacttg cgagtcaccg acagtcaggg ggcctcggac     2340

acagacactg ccactgtgga agtgcagcca gaccctagga agagtggcct ggtggagctg     2400

accctgcagg ttggtgttgg gcagctgaca gagcagcgga aggacaccct tgtgaggcag     2460

ctggctgtgc tgctgaacgt gctggactcg gacattaagg tccagaagat tcgggcccac     2520

tcggatctca gcaccgtgat tgtgttttat gtacagagca ggccgccttt caaggttctc     2580

aaagctgctg aagtggcccg aaatctgcac atgcggctct caaaggagaa ggctgacttc     2640

ttgcttttca aggtcttgag ggttgataca gcaggttgcc ttctgaagtg ttctggccat     2700

ggtcactgcg accccctcac aaagcgctgc atttgctctc acttatggat ggagaacctt     2760

atacagcgtt atatctggga tggagagagc aactgtgagt ggagt                     2805


<210>  3852
<211>  2646
<212>  DNA
<213>  Homo Sapiens

<400>  3852
gagagcaggt gccagcaggg gaagacacaa tttggagttg gcctgagatc tgggggagaa       60

aatcacctct ggcttcttga aggaaccccc tctctccagt catgtttggc tgcctgctgc      120

caggactctg cctgccatgt cttttggtgg ctagaaggga tgtgcattca ggcagactgc      180

agcaggcccc agagctgccg ggcttttagg acacactcct ccaattccat gctggtgttt      240

ttaaaaaaat tccaaactgc agatgatttg ggctttctac ctgaagatga tgtaccacat      300

cttctggggc taggttggaa ctgggcatct tggaggcaga gcccacccag agctgcactc      360

agacctgctg tatcttccag tgaccagcag agcttaatca ggaagcttca gaagagaggt      420

agtcccagtg acgtagttac acctatagtg acacagcatt ctaaagtgaa tgactccaac      480

gaattaggtg gtctgactac cagtggctct gcagaggtcc acaaggcgat tacaatttcc      540

agtcccctaa ccacagacct gactgcagag ctgtctggtg ggccaaagaa tgtatcagtg      600

caacctgaaa tatcagaggg tcttgctact acgcccagca ctcaacaagt aaaaagttct      660

gagaaaaccc agattgctgt cccccagcca gtggctccct cctacagtta tgctacccct      720

accccccagg cctctttcca gagcacctca gcaccatacc cagttataaa ggaactggtg      780

gtatctgctg gagagagtgt ccagataacc ctgcctaaga atgaagttca attaaatgca      840

tatgttctcc aagaaccacc taaaggagaa acctacacct acgactggca gctgattact      900

catcctagag actacagtgg agaaatggaa gggaaacatt cccagatcct caaactatcg      960

aagctcactc caggcctgta tgaattcaaa gtgattgtag agggtcaaaa tgcccatggg     1020

gaaggctatg tgaacgtgac agtcaagcca gagccccgta agaatcggcc ccccattgct     1080

attgtgtcac ctcagttcca ggagatctct ttgccaacca cttctacagt cattgatggc     1140

agtcaaagca ctgatgatga taaaatcgtt cagtaccatt gggaagaact taaggggcct     1200

ctaagagaag agaagatttc tgaagataca gccatattaa aactaagtaa actcgtccct     1260

gggaactaca ctttcagctt gactgtagta gactctgatg gagctaccaa ctctactact     1320

gcaaacctga cagtgaacaa agctgtggat tacccccctg tggccaacgc aggccccaac     1380

caagtgatca ccctgcccca aaactccatc accctctttg ggaaccagag cactgatgat     1440

catggcatca ccagctatga gtggtcactc agcccaagca gcaaagggaa agtggtggag     1500

atgcagggtg ttagaacacc aaccttacag ctctctgcga tgcaagaagg agactacact     1560

taccagctca cagtgactga cacaatagga cagcaggcca ctgctcaagt gactgttatt     1620

gtgcaacctg aaaacaataa gcctcctcag gcagatgcag gcccagataa agagctgacc     1680

cttcctgtgg atagcacaac cctggatggc agcaagagct cagatgatca gaaaattatc     1740

tcatatctct gggaaaaaac acagggacct gatggggtgc agctcgagaa tgctaacagc     1800

agtgttgcta ctgtgactgg gctgcaagtg gggacctatg tgttcacctt gactgtcaaa     1860

gatgagagga acctgcaaag ccagagctct gtgaatgtca ttgtcaaaga agaaataaac     1920

aaaccaccta tagccaagat aactgggaat gtggtgatta ccctacccac gagcacagca     1980

gagctggatg gctctaagtc ctcagatgac aagggaatag tcagctacct ctggactcga     2040

gatgagggga gcccagcagc aggggaggtg ttaaatcact ctgaccatca ccctatcctt     2100

tttctttcaa acctggttga gggaacctac acttttcacc tgaaagtgac cgatgcaaag     2160

ggtgagagtg acacagaccg gaccactgtg gaggtgaaac ctgatcccag gaaaaacaac     2220

ctggtggaga tcatcttgga tatcaacgtc agtcagctaa ctgagaggct gaaggggatg     2280

ttcatccgcc agattggggt cctcctgggg gtgctggatt ccgacatcat tgtgcaaaag     2340

attcagccgt acacggagca gagcaccaaa atggtatttt ttgttcaaaa cgagcctccc     2400

caccagatct tcaaaggcca tgaggtggca gcgatgctca agagtgagct gcggaagcaa     2460

aaggcagact ttttgatatt cagagccttg gaagtcaaca ctgtcacatg tcagctgaac     2520

tgttccgacc atggccactg tgactcgttc accaaacgct gtatctgtga ccctttttgg     2580

atggagaatt tcatcaaggt gcagctgagg gatggagaca gcaactgtga gtggagcgtg     2640

ttatat                                                                2646


<210>  3853
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3853
catgagggag tccacagaaa accttccctc ctggcccacc caggtcgcct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtca gatgtcaggt ttgagcactt ccttctgcac      120

agagaaggga agtttaagga cactttgcac ctcattggag agcaccatga tggggtctcc      180

aaagccaact tctccatcgg tcccatgatg caagaccttg cagggaccta cagatgctac      240

ggttctgtta ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatcgtc      300

atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttctggca      360

ggagagagcg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaggggg aggcccatga atgtaggttc tctgcagggc ccaaggtcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggaa cctacagatg cttcggctct      540

ttccgtgact ctccatacga gtggtcaaac tcgagtgacc cactgcttgt ttctgtcaca      600

ggaaaccctt caaatagttg gccttcaccc actgaaccaa gctctaaaac cggtaacccc      660

cgacacctgc ac                                                          672


<210>  3854
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3854
catgagggag tccacagaaa accttccctc ctggcccacc caggtcccct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtca gatgtcaggt ttcagcactt ccttctgcac      120

agagaaggga agtttaagga cactttgcac ctcattggag agcaccatga tggggtctcc      180

aaggccaact tctccatcgg tcccatgatg caagaccttg cagggaccta cagatgctac      240

ggttctgtta ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatcgtc      300

atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttctggca      360

ggagagagcg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaggggg aggcccatga acgtaggttc tctgcagggc ccaaggtcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggaa cctacagatg cttcggctct      540

ttccgtgact ctccatacga gtggtcaaac tcgagtgacc cactgcttgt ttctgtcaca      600

ggaaaccctt caaatagttg gctttcaccc actgaaccaa gctccgaaac cggtaacccc      660

agacacctgc at                                                          672


<210>  3855
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3855
catgagggag tccacagaaa accttccctc ctggcccacc caggtcccct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtca gatgtcaggt ttcagcactt ccttctgcac      120

agagaaggga agtttaagga cactttgcac ctcattggag agcaccatga tggggtctcc      180

aaggccaact tctccatcgg tcccatgatg caagaccttg cagggaccta cagatgctac      240

ggttctgtta ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatcgtc      300

atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttctggca      360

ggagagagcg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaggggg aggcccatga acgtaggttc tctgcagggc ccaaggtcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggaa cctacagatg cttcggctct      540

ttccgtgact ctccatacga gtggtcaaac tcgagtgacc cactgcttgt ttctgtcaca      600

ggaaaccctt caaatagttg gctttcaccc actgaaccaa gctccgaaac cggtaacccc      660

agacacctgc at                                                          672


<210>  3856
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  3856
tgggcacacg tgggtggtca ggacaagccc ttctgctctg cctggcccag cgctgtggtg       60

cctcaaggag gacacgtgac tcttcggtgt cactatcgtc gtgggtttaa catcttcacg      120

ctgtacaaga aagatggggt ccctgtccct gagctctaca acagaatatt ctggaacagt      180

ttcctcatta gccctgtgac cccagcacac gcagggacct acagatgtcg aggttttcac      240

ccgcactccc ccactgagtg gtcggcaccc agcaaccccc tggtgatcat ggtcacaggt      300

ctatatgaga aaccttcgct tacagcccgg ccgggcccca cggttcgcac aggagagaac      360

gtgaccttgt cctgcagctc ccagagctcc tttgacatct accatctatc cagggagggg      420

gaagcccatg aacttaggct ccctgcagtg cccagcatca atggaacatt ccaggccgac      480

ttccctctgg gtcctgccac ccacggagag acctacagat gcttcggctc tttccatgga      540

tctccctacg agtggtcaga cgcgagtgac ccactgcctg tttctgtcac aggaaaccct      600

tctagtagtt ggccttcacc cactgaacca agcttcaaaa ctggtatcgc cagacacctg      660

cat                                                                    663


<210>  3857
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  3857
catgagggtg gacaagacaa accgctgctt tccgcgtggc ccagtgcggt cgttccacgt       60

ggtggccatg tgacgttgct gtgtaggagc cgtctgggat tcacaatctt ttctctttac      120

aaagaagatg gggttccagt cccggaactt tataacaaaa tcttctggaa gtcaatattg      180

atggggcctg tgactcctgc acatgctggg acgtataggt gtagggggtc tcatccccgt      240

agcccgatcg agtggagtgc gccctctaac cctctggtaa tagtcgtcac gggcctgttc      300

ggcaaaccgt ccctgtctgc acagcctggc cctaccgtaa ggactggaga aaatgttgca      360

cttagctgtt catcccgttc cagcttcgat atgtaccatt tgtctcgtga aggacgtgcc      420

catgaaccaa gactacccgc tgttccttca gtcgatggaa ccttccaggc ggacttccca      480

cttggccccg ctacgcacgg aggcacatat acttgcttca gtagcctaca cgacagcccg      540

tacgaatgga gtgacccttc agacccatta ctggtctccg tgacggggaa ctcttcctcc      600

tcatccagta gcccgaccga gcccagttcc aaaacgggca ttagaaggca c               651


<210>  3858
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  3858
catgagggtg gacaggacaa gcccttgctg tctgcctggc ccagcgctgt ggtgcctcga       60

ggaggacatg tgactcttct gtgtcgctct cgtcttgggt ttaccatctt cagtctgtac      120

aaagaagatg gggtgcctgt ccctgagctc tacaacaaaa tattctggaa gagcatcctc      180

atgggccctg tgacccctgc acacgcaggg acctacagat gtcggggttc acacccgcgc      240

tcccccattg agtggtcggc acccagcaac cccctggtga tcgtggtcac aggtctattt      300

gggaaacctt cactctcagc ccagccgggc cccacggttc gcacaggaga gaacgtggcc      360

ttgtcctgca gctccaggag ctcatttgac atgtaccatc tatccaggga ggggagggcc      420

catgaaccta ggctccctgc agtgcccagc gtcgatggaa cattccaggc tgactttcct      480

ctgggccctg ccacccacgg agggacctac acatgcttca gctctctcca tgactcaccc      540

tatgagtggt cagacccgag tgacccactg cttgtttctg tcacaggaaa ctcttcaagt      600

agttcatctt cacccactga accaagctcc aaaactggta tccgcagaca c               651


<210>  3859
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3859
catgagggag tccacagaaa accttccctc ctggcccacc caggtcccct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtca gatgtcaggt ttgagcactt ccttctgcac      120

agagagggga agtataagga cactttgcac ctcattggag agcaccatga tggggtctcc      180

aaggccaact tctccatcgg tcccatgatg caagaccttg cagggaccta cagatgctac      240

ggttctgtta ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatcgtc      300

atcacaggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttttggca      360

ggagagagcg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaggggg aggcccatga acgtaggttc tctgcagggc ccaaggtcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggaa cctacagatg cttcggctct      540

ttccgtgact ctccctatga gtggtcaaac tcgagtgacc cactgcttgt ttctgtcaca      600

ggaaaccctt caaatagttg gccttcaccc actgaaccaa gctccaaaac cggtaacccc      660

agacacctgc at                                                          672


<210>  3860
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3860
cacgaggggt ttaggaggaa gccatcatta ttagcccacc ctggcaggct agtaaaatca       60

gaggaaacgg tgattcttca atgttggagt gacgttatgt ttgaacactt cttattacat      120

agagaaggga cgttcaacga tacattaaga ttgataggag agcacataga cggtgtctcc      180

aaagccaact tctcaattgg gcgtatgaga caggatttgg ccggtaccta tcgttgttat      240

ggcagtgttc ctcactcccc ctaccaattc agcgccccga gcgatcccct tgatatagta      300

atcacaggat tatatgagaa acccagtttg tcagcccaac cggggccgac cgttttggcg      360

ggcgagtcag tcactttatc atgtagttcc tggagctcct atgacatgta tcacctgtcc      420

actgaaggtg aagcacatga aagacgtttt tctgccggtc ccaaagtgaa tgggacattt      480

caggctgact ttccattagg acccgcaacc caagggggaa cctacaggtg ctttggtagt      540

ttccatgatt ccccctatga gtggtcaaag tcatccgatc ccctgttggt tagcgttact      600

gggaacccct caaactcatg gccctctccc actgagccgt cctccaaaac cggcaacccg      660

aggcacttac ac                                                          672


<210>  3861
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3861
caggagggag tccacagaaa accttccttc ctggccctcc caggtcacct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtcg gatgtcatgt ttgagcactt ccttctgcac      120

agagagggga agtttaacaa cactttgcac ctcattggag agcaccatga tggggtttcc      180

aaggccaact tctccattgg tcccatgatg cctgtccttg caggaaccta cagatgctac      240

ggttctgttc ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatggtg      300

atcataggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttcaggca      360

ggagagaatg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaagggg aggcccatga acgtaggctc cctgcagtgc gcagcatcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggga cctacagatg cttcggctct      540

ttccgtgacg ctccctacga gtggtcaaac tcgagtgatc cactgcttgt ttccgtcaca      600

ggaaaccctt caaatagttg gccttcaccc actgaaccaa gctccaaaac cggtaacccc      660

agacacctac at                                                          672


<210>  3862
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3862
caggagggag tccacagaaa accttccttc ctggccctcc caggtcacct ggtgaaatca       60

gaagagacag tcatcctgca atgttggtcg gatgtcatgt ttgagcactt ccttctgcac      120

agagagggga agtttaacaa cactttgcac ctcattggag agcaccatga tggggtttcc      180

aaggccaact tctccattgg tcccatgatg cctgtccttg caggaaccta cagatgctac      240

ggttctgttc ctcactcccc ctatcagttg tcagctccca gtgaccctct ggacatggtg      300

atcataggtc tatatgagaa accttctctc tcagcccagc cgggccccac ggttcaggca      360

ggagagaatg tgaccttgtc ctgcagctcc cggagctcct atgacatgta ccatctatcc      420

agggaagggg aggcccatga acgtaggctc cctgcagtgc gcagcatcaa cggaacattc      480

caggccgact ttcctctggg ccctgccacc cacggaggga cctacagatg cttcggctct      540

ttccgtgacg ctccctacga gtggtcaaac tcgagtgatc cactgcttgt ttccgtcaca      600

ggaaaccctt caaatagttg gccttcaccc actgaaccaa gctccaaaac cggtaacccc      660

agacacctac at                                                          672


<210>  3863
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3863
catgagggtt ttagacgtaa accgtctctg ctagcgcatc caggcccact agttaaaagc       60

gaagagacgg tgattttaca gtgctggagt gatgttatgt ttgaacattt ccttcttcac      120

agggagggta catttaacca caccttaaga cttattggtg agcacataga cggtgtgagc      180

aaaggcaact ttagtatagg acgtatgaca caagacctag caggcacata taggtgctat      240

gggtctgtca ctcattctcc gtaccagctt tccgccccca gtgacccctt agacatcgtg      300

attaccggcc tgtacgagaa gccctcattg ccagcacagc ccggtccaac agtcttagcc      360

ggcgagtctg tcacgctgtc ttgcagcagc agaagttcct acgatatgta tcatctatca      420

agagaaggtg aggcccatga gagaaggcta ccagcgggac caaaagtcaa cagaactttc      480

caggctgact ccccgctaga cccggcaacg cacggtgggg cgtataggtg ctttgggagc      540

ttcagagatt ccccctatga atggtccaag agttctgatc cgcttttagt cagtgtaact      600

ggtaatagta gtaactcttg gcccagtccg acggaacctt ctagcgagac gggaaacccc      660

aggcatttac ac                                                          672


<210>  3864
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3864
cacatgggtg gtcaggacaa gcccttcctg tctgcctggc ccagcgctgt ggtgcctcgc       60

ggaggacacg tgactcttcg gtgtcactat cgtcataggt ttaacaattt catgctatac      120

aaagaagaca gaatccacgt tcccatcttc catggcagaa tattccagga gggcttcaac      180

atgagccctg tgaccacagc acatgcaggg aactacacat gtcggggttc acacccacac      240

tcccccactg ggtggtcggc acccagcaac cccatggtga tcatggtcac aggaaaccac      300

agaaaacctt ccctcctggc ccacccaggt cccctggtga aatcaggaga gagagtcatc      360

ctgcaatgtt ggtcagatat catgtttgag cacttctttc tgcacaaaga ggggatctct      420

aaggacccct cacgcctcgt tggacagatc catgatgggg tctccaaggc caatttctcc      480

atcggtccca tgatgcttgc ccttgcaggg acctacagat gctacggttc tgttactcac      540

accccctatc agttgtcagc tcccagtgat cccctggaca tcgtggtcac aggtccatat      600

gagaaacctt ctctctcagc ccagccgggc cccaaggttc aggcaggaga gagcgtgacc      660

ttgtcctgta gctcccggag ctcctatgac atgtaccatc tatccaggga ggggggagcc      720

catgaacgta ggctccctgc agtgcgcaag gtcaacagaa cattccaggc agatttccct      780

ctgggccctg ccacccacgg agggacctac agatgcttcg gctctttccg tcactctccc      840

tacgagtggt cagacccgag tgacccactg cttgtttctg tcacaggaaa cccttcaagt      900

agttggcctt cacccacaga accaagctcc aaatctggta accccagaca cctgcac         957


<210>  3865
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3865
ctcatgggtg gtcaggacaa acccttcctg tctgcccggc ccagcactgt ggtgcctcga       60

ggaggacacg tggctcttca gtgtcactat cgtcgtgggt ttaacaattt catgctgtac      120

aaagaagaca gaagccacgt tcccatcttc cacggcagaa tattccagga gagcttcatc      180

atgggccctg tgaccccagc acatgcaggg acctacagat gtcggggttc acgcccacac      240

tccctcactg ggtggtcggc acccagcaac cccctggtga tcatggtcac aggaaaccac      300

agaaaacctt ccctcctggc ccacccaggg cccctgctga aatcaggaga gacagtcatc      360

ctgcaatgtt ggtcagatgt catgtttgag cacttctttc tgcacagaga ggggatctct      420

gaggacccct cacgcctcgt tggacagatc catgatgggg tctccaaggc caacttctcc      480

atcggtccct tgatgcctgt ccttgcagga acctacagat gttatggttc tgttcctcac      540

tccccctatc agttgtcagc tcccagtgac cccctggaca tcgtgatcac aggtctatat      600

gagaaacctt ctctctcagc ccagccgggc cccacggttc aggcaggaga gaacgtgacc      660

ttgtcctgta gctcctggag ctcctatgac atctaccatc tgtccaggga aggggaggcc      720

catgaacgta ggctccgtgc agtgcccaag gtcaacagaa cattccaggc agactttcct      780

ctgggccctg ccacccacgg agggacctac agatgcttcg gctctttccg tgccctgccc      840

tgcgtgtggt caaactcaag tgacccactg cttgtttctg tcacaggaaa cccttcaagt      900

agttggcctt cacccacaga accaagctcc aaatctggta tctgcagaca cctgcat         957


<210>  3866
<211>  891
<212>  DNA
<213>  Homo Sapiens

<400>  3866
caggacaagc ccttcctctc tgcctggccc ggcactgtgg tgtctgaagg acaacatgtg       60

actcttcagt gtcgctctca tcttgggttt aacgaattca gtctgtccaa agaagacggg      120

atgcctgtcc ctgagctcta caacagaata ttccggaaca gctttctcat gggccctgtg      180

accccagcac atgcagggac ctacagatgt tgcagttcac acccacactc ccccactggg      240

tggtcggcac ccagcaaccc tgtggtgatc atggtcacag gagtccacag aaaaccttcc      300

ctcctggccc acccaggtcc cctggtgaaa tcgggagaga cggtcatcct gcaatgttgg      360

tcagatgtca ggtttgagcg cttccttctg cacagagagg ggatcactga ggaccccttg      420

cgcctcgttg gacagctcca cgatgcgggt tcccaggtca actattccat gggtcccatg      480

acacctgccc ttgcagggac ctacagatgc tttggttctg tcactcactt accctatgag      540

ttgtcggctc ccagtgaccc tctggacatc gtggtcgtag gtctatatgg gaaaccttct      600

ctctcagccc agccgggccc cacggttcag gcaggagaga atgtgacctt gtcctgcagc      660

tcccggagct tgtttgacat ttaccatcta tccagggagg cagaggccgg tgaacttagg      720

ctcactgcgg tgctgagggt caatggaaca ttccaggcca acttccctct gggccctgtg      780

acccacggag ggaactacag atgcttcggc tctttccgtg ccctgcccca cgcgtggtca      840

gacccgagtg acccactgcc cgtttctgtc acaggtaact ccagatacct g               891


<210>  3867
<211>  921
<212>  DNA
<213>  Homo Sapiens

<400>  3867
cacgaagggg ggcaggacaa gccctttctg tcagcctggc cgtctcctgt tgtgtccgag       60

ggggagcatg tggccctaca gtgcagatcc aggttaggtt ttaacgaatt ttctctgtct      120

aaggaagacg gtatgcctgt gccggaacta tacaaccgtg tattccgtaa cactgttttt      180

attggtcccg tgaccccagc acacgctggc acttaccgtt gtagaggctc acatccgcat      240

ttccttactg gctggtccgc accttccaac cccttggtga taatggtaac cggcgtccac      300

cgtaaaccga gtctactggc gcatcccgga cccctagtta agagtgaaga gactgtgatc      360

cttcaatgtt ggagcgacgt gatgtttgaa cacttcctgc tgcataggga gggaaaattc      420

aacgacacgt tgaggttaac gggggagctt cacgacgggg tctcaaaggc gaacttctcc      480

atcggcagaa tgacccaaga cttagccgga acctatcgtt gctatgggtc tgtcccccac      540

tctccatatc agctatctgc gcctagtgat cccctggaca tagttattac ggggctatgt      600

ggcaagccaa gtctgtccgc gcagccaagg cccatggtta aagcagggga atcagtaaca      660

ttatcatgct ctagtcgtag ctcatacgat atctatcacc taagcaggga gggggaggct      720

catgagttga gattcccagc cgtcccaaaa gttaacggta ctttccaagc gaatttccca      780

ctaggaccgg ctacccatgg gggcacatac cgttgttttg gcagctttag agactccccc      840

tatgagtggt ccgatttatc agaccccctt cttgtgagcg taacagactc tatgaaggaa      900

aaaggtaagg atgtcatctt g                                                921


<210>  3868
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  3868
cacatgggtg gtcaggacaa gcccttcctg tctgcctggc ccagcgctgt ggtgcctcgc       60

ggaggacacg tgactcttcg gtgtcactat cgtcataggt ttaacaattt catgctatac      120

aaagaagaca gaatccacgt tcccatcttc catggcagaa tattccagga gggcttcaac      180

atgagccctg tgaccacagc acatgcaggg aactacacat gtcggggttc acacccacac      240

tcccccactg ggtggtcggc acccagcaac cccatggtga tcatggtcac aggaaaccac      300

agaaaacctt ccctcctggc ccacccaggt cccctggtga aatcaggaga gagagtcatc      360

ctgcaatgtt ggtcagatat catgtttgag cacttctttc tgcacaaaga gtggatctct      420

aaggacccct cacgcctcgt tggacagatc catgatgggg tctccaaggc caatttctcc      480

atcggttcca tgatgcgtgc ccttgcaggg acctacagat gctacggttc tgttactcac      540

accccctatc agttgtcagc tcccagtgat cccctggaca tcgtggtcac aggtctatat      600

gagaaacctt ctctctcagc ccagccgggc cccaaggttc aggcaggaga gagcgtgacc      660

ttgtcctgta gctcccggag ctcctatgac atgtaccatc tatccaggga ggggggagcc      720

catgaacgta ggctccctgc agtgcgcaag gtcaacagaa cattccaggc agatttccct      780

ctgggccctg ccacccacgg agggacctac agatgcttcg gctctttccg tcactctccc      840

tacgagtggt cagacccgag tgacccactg cttgtttctg tcacaggaaa cccttcaagt      900

agttggcctt cacccacaga accaagctcc aaatctggta acctcagaca cctgcac         957


<210>  3869
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  3869
caaaagattt gtccgcacgc aggagcacaa gataagttta gcttgtccgc ttggccatct       60

ccagtggtgc ccttgggagg tagggttacc ctaagctgcc actctcattt aaggttcgtg      120

atatggacca tctttcaaac taccgggaca cgttctcacg agctgcatac tggcttgagt      180

aacaatataa cgatatcccc ggtgacgccc gaacatgcgg gaacatatag atgtgtcggg      240

atttacaaac acgcctcaaa atggagtgcc gaaagtaact cattaaagat tatcgttacc      300

ggattgttca caaaaccctc catatcagca catccgtctt ctctagttca cgcgggtgct      360

agggtatcat taagatgtca ctccgagctt gcttttgacg agttcatttt gtataaagaa      420

gggcacatcc aacactccca gcagctggat cagggaatgg aagctggcat ccattatgtg      480

gaggcggtct tctcaatggg tcctgtaaca ccagcccatg ctggtgcgta ccgttgctgc      540

gggtgtttca gtcacagtcg ttacgagtgg tcagccccgt ccgatccatt ggatatcgtg      600

ataactggta aatataaaaa gccttctcta agtacgcagg tcgaccctat gatgcgtctt      660

ggggaaaagc taactttatt ctgcagctct gagatcagct tcgatcagta tcatttattt      720

aggcatggcg ttgcacatgg gcaatggctg agtggtggac aaagacatag ggaagcattc      780

caggctaact tcagtgtggg gagagctaca ccagtgcccg gagggacata caggtgttac      840

ggatcattta atgattcccc ttacaaacct ccagtgacga ggtgcaactt cacgcctcaa      900

gagacgttaa gagtactgct ttgtcatagc caaaatccac ccctaaatct aacacactta      960

gcattaaagg actcacctgc tacttgtata tgtagtttgg actctcag                  1008


<210>  3870
<211>  1449
<212>  DNA
<213>  Homo Sapiens

<400>  3870
caagggaccc agacccgctt cagccaggag ccagctgacc agacggtggt ggctggacag       60

cgggccgtgc tcccctgtgt gctgctcaac tactctggaa ttgtgcaatg gaccaaggac      120

gggctggccc tgggcatggg ccagggcctc aaagcctggc cacggtaccg ggttgtgggc      180

tccgcagacg ctgggcagta caacctggag atcacagatg ctgagctctc tgacgacgcc      240

tcttacgagt gccaggccac ggaggccgcc ctgcgctctc ggcgggccaa actcaccgtg      300

ctcatccccc cagaggacac caggattgac ggaggccctg tgattctact gcaggcaggc      360

accccccaca acctcacatg ccgggccttc aatgcgaagc ctgctgccac catcatctgg      420

ttccgggacg ggacgcagca ggagggcgct gtggccagca cggaattgct gaaggatggg      480

aagagggaga ccaccgtgag ccaactgctt attaacccca cggacctgga catagggcgt      540

gtcttcactt gccgaagcat gaacgaagcc atccctagtg gcaaggagac ttccatcgag      600

ctggatgtgc accaccctcc tacagtgacc ctgtccattg agccacagac ggtgcaggag      660

ggtgagcgtg ttgtctttac ctgccaggcc acagccaacc ccgagatctt gggctacagg      720

tgggccaaag ggggtttctt gattgaagac gcccacgaga gtcgctatga gacaaatgtg      780

gattattcct ttttcacgga gcctgtgtct tgtgaggttc acaacaaagt gggaagcacc      840

aatgtcagca ctttagtaaa tgtccacttt gctccccgga ttgtagttga ccccaaaccc      900

acaaccacag acattggctc tgatgtgacc cttacctgtg tctgggttgg gaatcccccc      960

ctcactctca cctggaccaa aaaggactca aatatggtcc tgagtaacag caaccagctg     1020

ctgctgaagt cggtgactca ggcagacgct ggcacctaca cctgccgggc catcgtgcct     1080

cgaatcggag tggctgagcg ggaggtgccg ctctatgtga acgggccccc catcatctcc     1140

agtgaggcag tgcagtatgc tgtgaggggt gacggtggca aggtggagtg tttcattggg     1200

agcacaccac ccccagaccg catagcatgg gcctggaagg agaacttctt ggaggtgggg     1260

accctggaac gctatacagt ggagaggacc aactcaggca gtggggtgct atccacgctc     1320

accatcaaca atgtcatgga ggccgacttt cagactcact acaactgcac cgcctggaac     1380

agcttcgggc caggcacagc catcatccag ctggaagagc gagaggtgtt acctgtgggc     1440

atcatagct                                                             1449


<210>  3871
<211>  1410
<212>  DNA
<213>  Homo Sapiens

<400>  3871
ggcccgtcgc cccatttcct gcaacagcca gaggacctgg tggtgctgct gggggaggaa       60

gcccggctgc cgtgtgctct gggcgcctac tgggggctag ttcagtggac taagagtggg      120

ctggccctag ggggccaaag ggacctacca gggtggtccc ggtactggat atcagggaat      180

gcagccaatg gccagcatga cctccacatt aggcccgtgg agctagagga tgaagcatca      240

tatgaatgtc aggctacaca agcaggcctc cgctccagac cagcccaact gcacgtgctg      300

gtccccccag aagcccccca ggtgctgggc ggcccctctg tgtctctggt tgctggagtt      360

cctgcgaacc tgacatgtcg gagccgtggg gatgcccgcc ctacccctga attgctgtgg      420

ttccgagatg gggtcctgtt ggatggagcc accttccatc agaccctgct gaaggaaggg      480

acccctgggt cagtggagag caccttaacc ctgcccacag gaagagacac agctatcaca      540

ctgagcctgc agtacccccc agaggtgact ctgtctgctt cgccacacac tgtgcaggag      600

ggagagaagg tcattttcct gtgccaggcc acagcccagc ctcctgtcac aggctacagg      660

tgggcaaaag ggggctctcc ggtgctcggg gcccgcgggc caaggttaga ggtcgtggca      720

gacgcctcgt tcctgactga gcccgtgtcc tgcgaggtca gcaacgccgt gggtagcgcc      780

aaccgcagta ctgcgctgga tgtgctgttt gggccgattc tgcaggcaaa gccggagccc      840

gtgtccgtgg acgtggggga agacgcttcc ttcagctgcg cctggcgcgg gaacccgctt      900

ccacgggtaa cctggacccg ccgcggtggc gcgcaggtgc tgggctctgg agccacactg      960

cgtcttccgt cggtggggcc cgaggacgca ggcgactatg tgtgcagagc tgaggctggg     1020

ctatcgggcc tgcggggcgg cgccgcggag gctcggctga ctgtgaacgc tcccccagta     1080

gtgaccgccc tgcactctgc gcctgccttc ctgaggggcc ctgctcgcct ccagtgtctg     1140

gttttcgcct ctcccgcccc agatgccgtg gtctggtctt gggatgaggg cttcctggag     1200

gcggggtcgc agggccggtt cctggtggag acattccctg ccccagagag ccgcggggga     1260

ctgggtccgg gcctgatctc tgtgctacac atttcgggga cccaggagtc tgactttagc     1320

aggagcttta actgcagtgc ccggaaccgg ctgggcgagg gaggtgccca ggccagcctg     1380

ggccgtagag acttgctgcc cactgtgcgg                                      1410


<210>  3872
<211>  1542
<212>  DNA
<213>  Homo Sapiens

<400>  3872
ctccagaaga gaggatgctg tctggtgctg ggctacatgg ccaaggacaa gtttcggaga       60

atgaatgaag gccaagtcta ttccttcagc cagcagcccc aggaccaggt ggtggtgtcg      120

ggacagccag tgacgctact ttgcgccatc cccgaatacg atggcttcgt tctgtggatc      180

aaggacggct tggctctggg tgtgggcagg gacctctcaa gttacccaca gtacctggtg      240

gtagggaacc acctgtcagg ggagcaccac ctgaagatcc tgagggcaga gctgcaagac      300

gatgcggtgt acgagtgcca ggccatccag gccgccatcc gctcccgccc cgcacgcctc      360

acagtcctgg tgccgcctga tgaccccgtc atcctggggg gccctgtgat cagcctgcgt      420

gcgggggacc ctctcaacct cacctgccac gcagacaatg ccaagcctgc agcctccatc      480

atctggttgc gaaagggaga ggtcatcaat ggggccacct actccaagac cctgcttcgg      540

gacggcaagc gggagagcat cgtcagcacc ctcttcatct cccctggtga cgtggagaat      600

ggccagagca tcgtgtgtcg tgccaccaac aaagccatcc ccggaggaaa ggagacgtcg      660

gtcaccattg acatccagca ccctccactg gtcaacctct cggtggagcc acagccagtg      720

ctggaggaca acgtcgtcac tttccactgc tctgcaaagg ccaacccagc tgtcacccag      780

tacaggtggg ccaagcgggg ccagatcatc aaggaggcat ctggagaggt gtacaggacc      840

acagtggact acacgtactt ctcagagccc gtctcctgtg aggtgaccaa cgccctgggc      900

agcaccaacc tcagccgcac ggttgacgtc tactttgggc cccggatgac cacagaaccc      960

caatccttgc tcgtggatct gggctctgat gccatcttca gctgcgcctg gaccggcaac     1020

ccatccctga ccatcgtctg gatgaagcgg ggctccggag tggtcctgag caatgagaag     1080

accctgaccc tcaaatccgt gcgccaggag gacgcgggca agtacgtgtg ccgggctgtg     1140

gtgccccgtg tgggagccgg ggagagagag gtgaccctga ccgtcaatgg accccccatc     1200

atctccagca cccagaccca gcacgccctc cacggcgaga agggccagat caagtgcttc     1260

atccggagca cgccgccgcc ggaccgcatc gcctggtcct ggaaggagaa cgttctggag     1320

tcgggcacat cggggcgcta tacggtggag accatcagca ccgaggaggg cgtcatctcc     1380

accctgacca tcagcaacat cgtgcgggcc gacttccaga ccatctacaa ctgcacggcc     1440

tggaacagct tcggctccga cactgagatc atccggctca aggagcaagg ttcggaaatg     1500

aagtcgggag ccgggctgga agcagagtct gtgccgatgg cc                        1542


<210>  3873
<211>  1497
<212>  DNA
<213>  Homo Sapiens

<400>  3873
caaccatctg tgagtccagg ggaaccgtct ccaccatcca tccatccagg aaaatcagac       60

ttaatagtcc gcgtgggcga cgagattagg ctgttatgca ctgatccggg ctttgtcaaa      120

tggacttttg agatcctgga tgaaacgaat gagaataagc agaatgaatg gatcacggaa      180

aaggcagaag ccaccaacac cggcaaatac acgtgcacca acaaacacgg cttaagcaat      240

tccatttatg tgtttgttag agatcctgcc aagcttttcc ttgttgaccg ctccttgtat      300

gggaaagaag acaacgacac gctggtccgc tgtcctctca cagacccaga agtgaccaat      360

tattccctca aggggtgcca ggggaagcct cttcccaagg acttgaggtt tattcctgac      420

cccaaggcgg gcatcatgat caaaagtgtg aaacgcgcct accatcggct ctgtctgcat      480

tgttctgtgg accaggaggg caagtcagtg ctgtcggaaa aattcatcct gaaagtgagg      540

ccagccttca aagctgtgcc tgttgtgtct gtgtccaaag caagctatct tcttagggaa      600

ggggaagaat tcacagtgac gtgcacaata aaagatgtgt ctagttctgt gtactcaacg      660

tggaaaagag aaaacagtca gactaaacta caggagaaat ataatagctg gcatcacggt      720

gacttcaatt atgaacgtca ggcaacgttg actatcagtt cagcgagagt taatgattct      780

ggagtgttca tgtgttatgc caataatact tttggatcag caaatgtcac aacaaccttg      840

gaagtagtag ataaaggatt cattaatatc ttccccatga taaacactac agtatttgta      900

aacgatggag aaaatgtaga tttgattgtt gaatatgaag cattccccaa acctgaacac      960

cagcagtgga tctatatgaa cagaaccttc actgataaat gggaagatta tcccaagtct     1020

gagaatgaaa gtaatatcag atacgtaagt gaacttcatc taacgagatt aaaaggcacc     1080

gaaggaggca cttacacatt cctagtgtcc aattctgacg tcaatgctgc catagcattt     1140

aatgtttatg tgaatacaaa accagaaatc ctgacttacg acaggctcgt gaatggcatg     1200

ctccaatgtg tggcagcagg attcccagag cccacaatag attggtattt ttgtccagga     1260

actgagcaga gatgctctgc ttctgtactg ccagtggatg tgcagacact aaactcatct     1320

gggccaccgt ttggaaagct agtggttcag agttctatag attctagtgc attcaagcac     1380

aatggcacgg ttgaatgtaa ggcttacaac gatgtgggca agacttctgc ctattttaac     1440

tttgcattta aaggtaacaa caaagagcaa atccatcccc acaccctgtt cactcct        1497


<210>  3874
<211>  495
<212>  DNA
<213>  Homo Sapiens

<400>  3874
gaagggatct gcaggaatcg tgtgactaat aatgtaaaag acgtcactaa attggtggca       60

aatcttccaa aagactacat gataaccctc aaatatgtcc ccgggatgga tgttttgcca      120

agtcattgtt ggataagcga gatggtagta caattgtcag acagcttgac tgatcttctg      180

gacaagtttt caaatatttc tgaaggcttg agtaattatt ccatcataga caaacttgtg      240

aatatagtgg atgaccttgt ggagtgcgtg aaagaaaact catctaagga tctaaaaaaa      300

tcattcaaga gcccagaacc caggctcttt actcctgaag aattctttag aatttttaat      360

agatccattg atgccttcaa ggactttgta gtggcatctg aaactagtga ttgtgtggtt      420

tcttcaacat taagtcctga gaaagattcc agagtcagtg tcacaaaacc atttatgtta      480

ccccctgttg cagcc                                                       495


<210>  3875
<211>  477
<212>  DNA
<213>  Homo Sapiens

<400>  3875
cagaaatcat caatagaaaa atgcagtgtg gacattcaac agagcaggaa taaaacaaca       60

gagagaccgg gtctcttaaa ctgcccaata tattggcagc aactccgaga gaaatgcttg      120

ttattttctc acactgtcaa cccttggaat aacagtctag ctgattgttc caccaaagaa      180

tccagcctgc tgcttattcg agataaggat gaattgatac acacacagaa cctgatacgt      240

gacaaagcaa ttctgttttg gattggatta aatttttcat tatcagaaaa gaactggaag      300

tggataaacg gctctttttt aaattctaat gacttagaaa ttagaggtga tgctaaagaa      360

aacagctgta tttccatctc acagacatct gtgtattctg agtactgtag tacagaaatc      420

agatggatct gccaaaaaga actaacacct gtgagaaata aagtgtatcc tgactct         477


<210>  3876
<211>  420
<212>  DNA
<213>  Homo Sapiens

<400>  3876
ccctctacat taatacagag gcacaacaat tcttccctga atacaagaac tcagaaagca       60

cgtcattgtg gccattgtcc tgaggagtgg attacatatt ccaacagttg ttactacatt      120

ggtaaggaaa gaagaacttg ggaagagagt ttgctggcct gtacttcgaa gaactccagt      180

ctgctttcta tagataatga agaagaaatg aaatttctgt ccatcatttc accatcctca      240

tggattggtg tgtttcgtaa cagcagtcat catccatggg tgacaatgaa tggtttggct      300

ttcaaacatg agataaaaga ctcagataat gctgaactta actgtgcagt gctacaagta      360

aatcgactta aatcagccca gtgtggatct tcaataatat atcattgtaa gcataagctt      420


<210>  3877
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  3877
attcctttcc tggagcagaa caattcttcc ccgaatacaa gaacgcagaa agcacgtcat       60

tgtggccatt gtcctgagga gtggattaca tattccaaca gttgttatta cattggtaag      120

gaaagaagaa cttgggaaga gagtttgctg gcctgtactt cgaagaactc cagtctgctt      180

tctatagata atgaagaaga aatgaaattt ctggccagca ttttaccttc ctcatggatt      240

ggtgtgtttc gtaacagcag tcatcatcca tgggtgacaa taaatggttt ggctttcaaa      300

cataagataa aagactcaga taatgctgaa cttaactgtg cagtgctaca agtaaatcga      360

cttaaatcag cccagtgtgg atcttcaatg atatatcatt gtaagcataa gctt            414


<210>  3878
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  3878
ataccatttt tggagcaaaa caacagctca cccaacgcga gaacgcaaaa ggcacgtcat       60

tgcggccatt gtcctgaaga gtggatcact tactccaatt cttgctatta cattgggaag      120

gagaggagga cgtgggagga gtctttacag gcttgcgcca gcaaaaacag tagtagtcta      180

ttatgtatcg acaacgaaga ggagatgaaa ttcttagcat ctatcttacc atccagttgg      240

ataggcgtgt ttagaaacag ctcacaccat ccctgggtca caattaatgg cctggcattc      300

aaacatgaga tcaaggactc agatcatgct gagaggaact gtgctatgct acatgtccgt      360

ggtttgatct cagaccagtg cggtagctcc aggattatta gaagaggttt cattatgcta      420

accaggttgg tactaaattc a                                                441


<210>  3879
<211>  444
<212>  DNA
<213>  Homo Sapiens

<400>  3879
aaaaattctt ttactaaact gagtattgag ccagcattta ctccaggacc caacatagaa       60

ctccagaaag actctgactg ctgttcttgc caagaaaaat gggttgggta ccggtgcaac      120

tgttacttca tttccagtga acagaaaact tggaacgaaa gtcggcatct ctgtgcttct      180

cagaaatcca gcctgcttca gcttcaaaac acagatgaac tggattttat gagctccagt      240

caacaatttt actggattgg actctcttac agtgaggagc acaccgcctg gttgtgggag      300

aatggctctg cactctccca gtatctattt ccatcatttg aaacttttaa tacaaagaac      360

tgcatagcgt ataatccaaa tggaaatgct ttagatgaat cctgtgaaga taaaaatcgt      420

tatatctgta agcaacagct catt                                             444


<210>  3880
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  3880
ttacttgtca gccaaggagt gcttttgaaa tgccaaaagg ggagttgcag caatgctaca       60

caatatgagg acactggtga tctgaaagta aataacggta cacgtcgtaa tatttcaaac      120

aaggatctgt gcgcttctcg ttcagcagat caaaccgtat tgtgtcaaag tgagtggctg      180

aagtaccaag gcaaatgttg ttattggttc tccaacgaga tgaagtcttg gtctgatagc      240

tatgtttatt gcttggagcg taagtcacac ttgctaatta tacacgacca gttagagatg      300

gcctttattc agaagaatct tagacagttg aactacgtct ggatagggct aaactttaca      360

tctctaaaaa tgacctggac gtgggtggac ggaagcccta tagatagcaa gatctttttc      420

atcaagggac cagctaaaga aaatagttgc gcagctatca aagagtctaa aattttcagc      480

gagacttgta gtagcgtgtt taaatggata tgtcagtat                             519


<210>  3881
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  3881
gaccttaaat tttggcataa gaagatggat ttcagtcaaa atgtcaatgt ttcatcctta       60

tctggtcaca actacctatg cccaaatgat tggcttctaa acgaaggtaa gtgttactgg      120

ttctctacca gcttcaaaac gtggaaagaa agtcaacgtg attgtaccca gctacaagcg      180

cacctactag ttatccagaa tcttgacgaa ctagagttca ttcaaaatag tcttaaaccc      240

ggccacttcg ggtggatcgg gttatatgta acatttcagg gcaatttatg gatgtggatc      300

gatgaacatt ttctggtgcc ggagctgttt agcgttatag ggcctacgga cgacaggagc      360

tgcgcggtca taacgggaaa ttgggtgtat tcagaagact gtagttcaac ttttaagggg      420

atttgtcaaa gagacgcaat actgacacat aatggtactt caggggtt                   468


<210>  3882
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  3882
ctgtgccagg gctccaacta ctccacttgt gccagctgtc ctagctgccc agaccgctgg       60

atgaaatatg gtaaccattg ttattatttc tcagtggagg aaaaggactg gaattctagt      120

ctggaattct gcctagccag agactcacac ctccttgtga taacggacaa tcaggaaatg      180

agcctgctcc aagttttcct cagtgaggcc ttttgctgga ttggtctgag gaacaattct      240

ggctggaggt gggaagatgg atcacctcta aacttctcaa ggatttcttc taatagcttt      300

gtgcagacat gcggtgccat caacaaaaat ggtcttcaag cctcaagctg tgaagttcct      360

ttacactggg tgtgtaagaa gtgtcccttt gcagatcaag ctttattc                   408


<210>  3883
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  3883
atatggagtg ctgtattcct aaactcatta ttcaaccaag aagttcaaat tcccttgacc       60

gaaagttact gtggcccatg tcctaaaaac tggatatgtt acaaaaataa ctgctaccaa      120

ttttttgatg agagtaaaaa ctggtatgag agccaggctt cttgtatgtc tcaaaatgcc      180

agccttctga aagtatacag caaagaggac caggatttac ttaaactggt gaagtcatat      240

cattggatgg gactagtaca cattccaaca aatggatctt ggcagtggga agatggctcc      300

attctctcac ccaacctact aacaataatt gaaatgcaga agggagactg tgcactctat      360

gcctcgagct ttaaaggcta tatagaaaac tgttcaactc caaatacata catctgcatg      420

caaaggactg tg                                                          432


<210>  3884
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  3884
caggccccga ggcaaaagca aggaagcact ggggaggaat tccatttcca gactggaggg       60

agagattcct gcactatgcg tcccagcagc ttggggcaag gtgctggaga agtctggctt      120

cgcgtcgact gccgcaacac agaccagacc tactggtgtg agtacagggg gcagcccagc      180

atgtgccagg cttttgctgc tgaccccaaa ccttactgga atcaagccct gcaggagctg      240

aggcgccttc accatgcgtg ccagggggcc ccggtgctta ggccatccgt gtgcagggag      300

gctggacccc aggcccatat gcagcaggtg acttccagcc tcaagggcag cccagagccc      360

aaccagcagc ctgaggctgg gacgccatct ctgaggccca aggccacagt gaaactcaca      420

gaagcaacac agctgggaaa ggactcgatg gaagagctgg gaaaagccaa acccaccacc      480

cgacccacag ccaaacctac ccagcctgga cccaggcccg gagggaatga ggaagcaaag      540

aagaaggcct gggaacattg ttggaaaccc ttccaggccc tgtgcgcctt tctcatcagc      600

ttcttccgag gg                                                          612


<210>  3885
<211>  3303
<212>  DNA
<213>  Homo Sapiens

<400>  3885
atccagatcc ccgaggaata tgaaggacac catgtgatgg agccacctgt catcacggaa       60

cagtctccac ggcgcctggt tgtcttcccc acagatgaca tcagcctcaa gtgtgaggcc      120

agtggcaagc ccgaagtgca gttccgctgg acgagggatg gtgtccactt caaacccaag      180

gaagagctgg gtgtgaccgt gtaccagtcg ccccactctg gctccttcac catcacgggc      240

aacaacagca actttgctca gaggttccag ggcatctacc gctgctttgc cagcaataag      300

ctgggcaccg ccatgtccca tgagatccgg ctcatggccg agggtgcccc caagtggcca      360

aaggagacag tgaagcccgt ggaggtggag gaaggggagt cagtggttct gccttgcaac      420

cctcccccaa gtgcagagcc tctccggatc tactggatga acagcaagat cttgcacatc      480

aagcaggacg agcgggtgac gatgggccag aacggcaacc tctactttgc caatgtgctc      540

acctccgaca accactcaga ctacatctgc cacgcccact tcccaggcac caggaccatc      600

attcagaagg aacccattga cctccgggtc aaggccacca acagcatgat tgacaggaag      660

ccgcgcctgc tcttccccac caactccagc agccacctgg tggccttgca ggggcagcca      720

ttggtcctgg agtgcatcgc cgagggcttt cccacgccca ccatcaaatg gctgcgcccc      780

agtggcccca tgccagccga ccgtgtcacc taccagaacc acaacaagac cctgcagctg      840

ctgaaagtgg gcgaggagga tgatggcgag taccgctgcc tggccgagaa ctcactgggc      900

agtgcccggc atgcgtacta tgtcaccgtg gaggctgccc cgtactggct gcacaagccc      960

cagagccatc tatatgggcc aggagagact gcccgcctgg actgccaagt ccagggcagg     1020

ccccaaccag aggtcacctg gagaatcaac gggatccctg tggaggagct ggccaaagac     1080

cagaagtacc ggattcagcg tggcgccctg atcctgagca acgtgcagcc cagtgacaca     1140

atggtgaccc aatgtgaggc ccgcaaccgg cacgggctct tgctggccaa tgcctacatc     1200

tacgttgtcc agctgccagc caagatcctg actgcggaca atcagacgta catggctgtc     1260

cagggcagca ctgcctacct tctgtgcaag gccttcggag cgcctgtgcc cagtgttcag     1320

tggctggacg aggatgggac aacagtgctt caggacgaac gcttcttccc ctatgccaat     1380

gggaccctgg gcattcgaga cctccaggcc aatgacaccg gacgctactt ctgcctggct     1440

gccaatgacc aaaacaatgt taccatcatg gctaacctga aggttaaaga tgcaactcag     1500

atcactcagg ggccccgcag cacaatcgag aagaaaggtt ccagggtgac cttcacgtgc     1560

caggcctcct ttgacccctc cttgcagccc agcatcacct ggcgtgggga cggtcgagac     1620

ctccaggagc ttggggacag tgacaagtac ttcatagagg atgggcgcct ggtcatccac     1680

agcctggact acagcgacca gggcaactac agctgcgtgg ccagtaccga actggatgtg     1740

gtggagagta gggcacagct cttggtggtg gggagccctg ggccggtgcc acggctggtg     1800

ctgtccgacc tgcacctgct gacgcagagc caggtgcgcg tgtcctggag tcctgcagaa     1860

gaccacaatg cccccattga gaaatatgac attgaatttg aggacaagga aatggcgcct     1920

gaaaaatggt acagtctggg caaggttcca gggaaccaga cctctaccac cctcaagctg     1980

tcgccctatg tccactacac ctttagggtt actgccataa acaaatatgg ccccggggag     2040

cccagcccgg tctctgagac tgtggtcaca cctgaggcag ccccagagaa gaaccctgtg     2100

gatgtgaagg gggaaggaaa tgagaccacc aatatggtca tcacgtggaa gccgctccgg     2160

tggatggact ggaacgcccc ccaggttcag taccgcgtgc agtggcgccc tcaggggaca     2220

cgagggccct ggcaggagca gattgtcagc gaccccttcc tggtggtgtc caacacgtcc     2280

accttcgtgc cctatgagat caaagtccag gccgtcaaca gccagggcaa gggaccagag     2340

ccccaggtca ctatcggcta ctctggagag gactaccccc aggcaatccc tgagctggaa     2400

ggcattgaaa tcctcaactc aagtgccgtg ctggtcaagt ggcggccggt ggacctggcc     2460

caggtcaagg gccacctccg cggatacaat gtgacgtact ggagggaggg cagtcagagg     2520

aagcacagca agagacatat ccacaaagac catgtggtgg tgcccgccaa caccaccagt     2580

gtcatcctca gtggcttgcg gccctatagc tcctaccacc tggaggtgca ggcctttaac     2640

gggcgaggat cggggcccgc cagcgagttc accttcagca ccccagaggg agtgcctggc     2700

caccccgagg cgttgcacct ggagtgccag tcgaacacca gcctgctgct gcgctggcag     2760

cccccactca gccacaacgg cgtgctcacc ggctacgtgc tctcctacca ccccctggat     2820

gaggggggca aggggcaact gtccttcaac cttcgggacc ccgaacttcg gacacacaac     2880

ctgaccgatc tcagccccca cctgcggtac cgcttccagc ttcaggccac caccaaagag     2940

ggccctggtg aagccatcgt acgggaagga ggcactatgg ccttgtctgg gatctcagat     3000

tttggcaaca tctcagccac agcgggtgaa aactacagtg tcgtctcctg ggtccccaag     3060

gagggccagt gcaacttcag gttccatatc ttgttcaaag ccttgggaga agagaagggt     3120

ggggcttccc tttcgccaca gtatgtcagc tacaaccaga gctcctacac gcagtgggac     3180

ctgcagcctg acactgacta cgagatccac ttgtttaagg agaggatgtt ccggcaccaa     3240

atggctgtga agaccaatgg cacaggccgc gtgaggctcc ctcctgctgg cttcgccact     3300

gag                                                                   3303


<210>  3886
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  3886
gtcccggtgg tgtgggccca ggagggggct cctgcccagc tcccctgcag ccccacaatc       60

cccctccagg atctcagcct tctgcgaaga gcaggggtca cttggcagca tcagccagac      120

agtggcccgc ccgctgccgc ccccggccat cccctggccc ccggccctca cccggcggcg      180

ccctcctcct gggggcccag gccccgccgc tacacggtgc tgagcgtggg tcccggaggc      240

ctgcgcagcg ggaggctgcc cctgcagccc cgcgtccagc tggatgagcg cggccggcag      300

cgcggggact tctcgctatg gctgcgccca gcccggcgcg cggacgccgg cgagtaccgc      360

gccgcggtgc acctcaggga ccgcgccctc tcctgccgcc tccgtctgcg cctgggccag      420

gcctcgatga ctgccagccc cccaggatct ctcagagcct ccgactgggt cattttgaac      480

tgctccttca gccgccctga ccgcccagcc tctgtgcatt ggttccggaa ccggggccag      540

ggccgagtcc ctgtccggga gtccccccat caccacttag cggaaagctt cctcttcctg      600

ccccaagtca gccccatgga ctctgggccc tggggctgca tcctcaccta cagagatggc      660

ttcaacgtct ccatcatgta taacctcact gttctgggtc tggagccccc aactcccttg      720

acagtgtacg ctggagcagg ttccagggtg gggctgccct gccgcctgcc tgctggtgtg      780

gggacccggt ctttcctcac tgccaagtgg actcctcctg ggggaggccc tgacctcctg      840

gtgactggag acaatggcga ctttaccctt cgactagagg atgtgagcca ggcccaggct      900

gggacctaca cctgccatat ccatctgcag gaacagcagc tcaatgccac tgtcacattg      960

gcaatcatca caggtcagcc tcaggtggga aaggag                                996


<210>  3887
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  3887
caggaggaag atctgcccag accctccatc tcggctgagc caggcaccgt gatccccctg       60

gggagccatg tgactttcgt gtgccggggc ccggttgggg ttcaaacatt ccgcctggag      120

agggagagta gatccacata caatgatact gaagatgtgt ctcaagctag tccatctgag      180

tcagaggcca gattccgcat tgactcagta agtgaaggaa atgccgggcc ttatcgctgc      240

atctattata agccccctaa atggtctgag cagagtgact acctggagct gctggtgaaa      300

gaaacctctg gaggcccgga ctccccggac acagagcccg gctcctcagc tggacccacg      360

cagaggccgt cggacaacag tcacaatgag catgcacctg cttcccaagg cctgaaagct      420

gagcatctgt at                                                          432


<210>  3888
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  3888
caggaggggg cccttcccag accctccatc tcggctgagc caggcactgt gatctccccg       60

gggagccatg tgactttcat gtgccggggc ccggttgggg ttcaaacatt ccgcctggag      120

agggaggata gagccaagta caaagatagt tataatgtgt ttcgacttgg tccatctgag      180

tcagaggcca gattccacat tgactcagta agtgaaggaa atgccgggct ttatcgctgc      240

ctctattata agccccctgg atggtctgag cacagtgact tcctggagct gctggtgaaa      300

gaaagctctg gaggcccgga ctccccggac acagagcccg gctcctcagc tgggactgtg      360

ccaggcactg aagcctccgg atttgatgca cca                                   393


<210>  3889
<211>  7719
<212>  DNA
<213>  Homo Sapiens

<400>  3889
tgcttctgct ttggcgtttc tgatgtctgc agcagcctct cttggcctgt tggtcaggta       60

aacagtatgt ccgggtggct ggtcaccgac ttgatcagtc ccaggaagat cccgtctcag      120

caagatgcac taggcgggcg ccatcaggtc agcatcaaca acaccgcggt catgcagaga      180

ctggctccca agtactactg ggcagccccc gaggcctacc ttggaaataa gctgactgcg      240

tttggcggat tcctgaaata cacggtgtcc tacgatattc cggtagagac ggtagacagt      300

aacctcatgt cgcatgctga cgtcatcatt aagggaaacg gactcacttt aagcacacag      360

gctgagggtc tgtcattgca gccttatgaa gagtacctaa acgtggttag acttgtgcct      420

gaaaacttcc aagattttca cagcaaaagg cagattgatc gtgaccagct gatgactgtc      480

attgccaatg tgacacatct tttgatcaga gccaactaca attctgcaaa aatggctctt      540

tacaggttgg agtccgtctc tctggacata gccagctcta atgccatcga cctggtggtg      600

gctgctgatg tggagcactg tgaatgtccg caaggctaca cagggacctc ctgtgagtcg      660

tgcctctctg gctattaccg cgtggatgga atactctttg gaggaatttg tcaaccctgt      720

gaatgccacg gccatgcagc tgagtgtaat gttcacggcg tttgcattgc gtgtgcgcac      780

aacaccaccg gcgtccactg tgagcagtgc ttgcccggct tctacgggga gccttcccga      840

gggacacctg gggactgcca gccctgcgcc tgccctctca ccatagcctc caacaatttc      900

agccccacct gccacctcaa tgatggagat gaagtggtct gtgactggtg tgccccgggc      960

tactcaggag cttggtgtga gagatgcgca gatggttact atggaaaccc aacagtgcct     1020

ggcgaatctt gtgttccctg tgactgcagc ggcaacgtgg acccctcgga ggctggtcac     1080

tgtgactcag tcaccgggga gtgcctgaag tgcctgggga acacagatgg cgcccactgt     1140

gaaaggtgtg ctgacgggtt ctatggggac gctgtgacag ccaagaactg ccgcgcctgt     1200

gaatgccatg tgaaaggctc ccattctgcc gtgtgccatc ttgagaccgg gctctgcgac     1260

tgcaaaccaa acgtgactgg acagcagtgt gaccagtgct tgcatggcta ttatgggctg     1320

gactcaggcc atggctgccg gccctgcaac tgcagcgtgg caggctccgt gtcagatggc     1380

tgcacggatg aaggccagtg tcactgtgtc ccaggtgtgg cagggaaaag gtgtgacagg     1440

tgtgcccatg gcttctacgc ctaccaggat ggtagctgta caccctgtga ctgcccacac     1500

actcagaata cctgcgaccc agaaactgga gagtgtgtct gcccccctca cacacagggt     1560

gtgaagtgtg aagaatgtga ggatgggcac tggggctacg atgcggaggt ggggtgccag     1620

gcctgcaatt gcagtctcgt ggggtcgact catcatcggt gcgatgtggt caccggccat     1680

tgccagtgca agtcaaaatt tggtggccgg gcctgcgatc agtgttcctt gggttacaga     1740

gactttcccg actgtgttcc ctgtgactgt gacctgaggg ggacgtcggg ggacgcctgc     1800

aacctggagc agggtctctg cggctgtgtg gaggaaaccg gggcctgccc ttgcaaggaa     1860

aatgtctttg gccctcagtg caacgaatgt cgagagggca ccttcgctct ccgcgcagac     1920

aaccccctgg gctgcagccc gtgcttctgc tccgggctgt cccacctctg ctcagagctg     1980

gaggactacg tgaggacccc agtaacgctg ggctccgatc agcctcttct gcgtgtggtt     2040

tctcagagta acttgagggg cacgactgag ggggtttact accaggcccc cgacttcctg     2100

ctggatgccg ccaccgtccg gcagcacatc cgtgcagagc cgttttactg gcggctgccg     2160

cagcagttcc aaggagacca gctcatggcc tatggtggca aactgaagta cagcgtggcc     2220

ttctattctt tggatggcgt cggcacctcc aattttgagc ctcaagttct catcaaaggt     2280

ggtcggatca gaaagcaagt catttacatg gatgcaccag ccccagagaa tggagtgaga     2340

caggaacaag aagtagcaat gagagagaat ttttggaaat attttaactc tgtttctgaa     2400

aaacctgtca cgcgagagga ttttatgtct gtcctcagcg atattgagta catcctcatc     2460

aaggcatcgt atggtcaagg attacagcag agcagaatct cagacatttc aatggaggtt     2520

ggcagaaagg ctgaaaagct gcacccagaa gaagaggttg catctctttt agagaattgt     2580

gtctgtcctc ctggcactgt gggattctca tgtcaggact gcgcccctgg gtaccacaga     2640

gggaagctcc cagcagggag tgacagggga ccacgccctc tggttgctcc ttgtgttccc     2700

tgcagttgca acaaccacag tgacacctgt gaccccaaca ccgggaagtg tctgaactgt     2760

ggcgataaca cagcaggtga ccattgtgat gtgtgtactt ctggctacta cgggaaggtg     2820

actggctcag caagtgactg tgctctgtgt gcctgtcctc acagccctcc tgccagtttt     2880

agtcccactt gtgtcttgga aggggaccac gatttccgtt gtgacgcctg tctcctgggc     2940

tatgaaggaa aacactgtga aaggtgctcc tcgagctatt atgggaaccc tcaaacacca     3000

ggtggcagtt gccagaagtg tgactgcaac ccgcacggct ctgtccacgg tgactgtgac     3060

cgcacatctg ggcagtgcgt ttgcaggctg ggggcctcgg ggctccggtg cgatgagtgt     3120

gaaccgaggc acattctgat ggaaacagat tgtgtttcct gtgatgatga gtgtgtaggt     3180

gtgctgctga atgacttgga tgagattggt gatgccgttc tttctctgaa cctcgctggc     3240

attatccctg tcccatatgg aattttgtca aacctggaaa atacaactaa atatctccag     3300

gaatctttat taaaagaaaa tatgcaaaag gacctgggaa aaattaagct tgaaggtgtt     3360

gcagaagaaa cggacaacct gcaaaagaag ctcactagga tgttagcgag tacccaaaag     3420

gtgaataggg caactgagag aatcttcaag gagagtcaag acctggccat agccattgag     3480

aggctgcaga tgagcatcac agaaattatg gaaaagacaa ctttaaatca gactttggat     3540

gaagatttcc tactacccaa ttctactctt cagaacatgc aacagaatgg tacatctttg     3600

ctagaaatca tgcagataag agacttcaca cagttgcacc aaaatgccac ccttgaactc     3660

aaggctgctg aagatttatt gtcacaaatt caggaaaatt accagaagcc gctggaagaa     3720

ttggaggtat tgaaagaagc agcaagccac gtcctttcaa agcacaacaa tgaactaaag     3780

gcggctgagg cgctcgtgag ggaagctgag gcaaagatgc aggaaagcaa ccacctgctg     3840

ctcatggtca atgctaatct gagagaattc agtgataaaa agctgcatgt tcaagaagaa     3900

caaaatctga cctcagagct cattgtccaa ggaagaggat tgatagatgc tgctgctgca     3960

caaacagatg ctgtacaaga tgctctagag cacttagagg atcaccagga taagctactt     4020

ttatggtctg ccaaaatcag gcaccacata gatgacctgg tcatgcacat gtcccaaagg     4080

aacgcagtcg acctggtcta cagagctgag gaccatgccg ctgagttcca gagactagca     4140

gatgttctgt acagtggcct tgaaaacatc agaaatgtgt ccctgaatgc caccagtgca     4200

gcctatgtcc attacaacat ccagagcctg attgaagaat cggaggaact ggccagagat     4260

gctcacagga ctgtgactga gacgagcctg ctctcagaat cccttgtttc taacgggaaa     4320

gcggccgtgc agcgcagctc cagatttcta aaagaaggca acaacctcag caggaagctt     4380

ccaggtattg cattggaact gagtgaattg agaaataaga caaacagatt tcaagagaat     4440

gctgttgaaa ttaccaggca aaccaatgaa tcactcttga tacttagagc aattcctaaa     4500

ggtataagag acaagggagc caaaaccaaa gagctggcca cgtctgcaag ccagagcgcg     4560

gtgagcacgc tgagggacgt ggcggggctg agccaggagc tgctgaacac atctgccagc     4620

ctgtccaggg tcaacaccac attacgagag acacaccagc ttctgcagga ctccaccatg     4680

gccactctgt tggctggaag aaaagtcaaa gacgtggaaa ctcaagccaa ccttttgttt     4740

gatcggttga agcctttgaa gatgttagag gagaatctga gcagaaacct atcagaaatt     4800

aaactgttga tcagccaggc ccgcaaacaa gcagcttcta ttaaagtcgc cgtgtctgca     4860

gacagagatt gcatccgggc ctaccagcct cagatttcct ctaccaacta caatacctta     4920

acactaaatg ttaagacaca ggaacccgat aatcttctct tctacctcgg tagcagcacc     4980

gcttctgatt tccttgcagt ggagatgcgg cgagggagag tggccttcct gtgggacctg     5040

ggctccgggt ccacacgctt ggagtttcca gactttccca ttgatgacaa cagatggcac     5100

agtatccatg tagccagatt tggaaacatt ggttcactga gtgtaaagga aatgagctca     5160

aatcaaaagt caccaacaaa aacaagtaaa tcccctggga cagctaatgt tctggatgta     5220

aacaattcaa cactcatgtt tgttggaggt cttggaggac aaatcaagaa atctcctgct     5280

gtgaaggtta ctcattttaa aggctgcttg ggggaggcct tcctgaatgg aaaatccata     5340

ggcctatgga actatattga aagggaaggc aagtgccgtg ggtgcttcgg aagctcccag     5400

aatgaagacc cttccttcca ttttgacggg agtgggtact ctgtcgtgga gaagtcactt     5460

ccggctaccg tgacccagat aatcatgctt tttaatacct tttcacctaa tggacttctt     5520

ctctacctgg gttcatacgg cacaaaagac tttttatcca tcgagctgtt tcgtggcaga     5580

gtgaaggtta tgactgacct gggttcagga cccattaccc ttttgacaga cagacgttat     5640

aacaatggaa cctggtacaa aattgccttc cagcgaaacc ggaagcaagg agtgctagca     5700

gttatcgatg cctataacac cagtaataaa gaaaccaagc agggcgagac tccgggagca     5760

tcttctgacc tcaaccgcct agacaaggac ccgatttatg tgggtggatt accaaggtca     5820

agagttgtaa ggagaggtgt caccaccaaa agctttgtgg gctgcatcaa gaacctggaa     5880

atatccagat caacctttga cttactcaga aattcctatg gagtgagaaa aggctgttta     5940

ctggagccca tccggagtgt tagcttcctg aaaggcggct acattgaatt gccacccaaa     6000

tctttgtcac cagaatcaga atggctggta acatttgcca ccacgaacag cagtggcatc     6060

atcctggctg ccctcggcgg ggatgtggag aagcggggtg atcgtgagga agcacacgtg     6120

cccttctttt ccgtcatgct gatcggaggc aacattgagg tacatgtcaa tcctggggat     6180

gggacaggcc tgagaaaagc tctcctgcac gctcccacgg gtacctgcag tgatggacaa     6240

gcgcattcca tctccttggt caggaatcgg agaattatca ctgtccaatt ggatgagaac     6300

aatcctgtgg aaatgaagtt gggcacatta gtagaaagca ggacgataaa tgtgtccaat     6360

ctgtacgtcg ggggaattcc agagggagag gggacgtcac tgctcacaat gagaagatcg     6420

ttccatggct gtatcaaaaa cctgatcttc aatttggaac ttttggattt caacagtgca     6480

gttggccatg agcaagtcga cctggacacc tgctggctgt cagaaaggcc taagctggct     6540

cccgatgcag aggacagcaa gctcttgcca gagccccggg cttttccaga acagtgtgtg     6600

gtggatgcag ctctggagta cgttcccggc gctcaccagt ttggtctcac acaaaacagc     6660

catttcatct tgccttttaa tcagtcggct gtcagaaaga agctctcggt tgagctaagc     6720

atccgcacgt tcgcctccag cggcctgatt tactacatgg ctcatcagaa ccaagcagac     6780

tacgctgtgc tccagctgca cgggggccgc ctccacttca tgtttgacct tggcaaaggc     6840

agaacaaagg tctctcaccc tgcactgctc agtgatggca agtggcacac ggtcaagaca     6900

gactatgtta aaagaaaagg cttcataact gtcgacggcc gagagtctcc catggtgact     6960

gtggtgggag atggaaccat gctggatgtg gagggtttgt tctacctagg aggcctgccc     7020

tcccagtacc aggccaggaa aattggaaat atcacccaca gcatccctgc ctgcattggg     7080

gatgtgacgg ttaacagcaa acagctggac aaggacagcc cggtgtctgc cttcacggtg     7140

aacaggtgct acgcagtggc ccaggaagga acatactttg acggaagcgg atatgcagct     7200

cttgtcaaag agggctacaa agtccagtca gatgtgaaca tcacactgga gtttcgaacc     7260

tcctcgcaga atggcgtcct cctggggatc agcactgcca aagtggatgc cattggacta     7320

gagcttgtgg acggcaaggt cttgttccat gtcaacaatg gtgctggcag gataacagct     7380

gcatatgagc ccaaaaccgc cactgtgctc tgtgatggaa aatggcacac tcttcaagct     7440

aacaaaagca aacaccgtat cactctgatt gttgacggga acgcagttgg cgctgaaagt     7500

ccacacaccc agtctacctc agtggacacc aacaatccca tttatgttgg tggctatcct     7560

gctggtgtga agcaaaaatg cctgcgcagc cagacctcgt tccgcgggtg tttgaggaag     7620

ctagctctga ttaagagccc gcaggtgcag tcctttgact tcagcagagc gttcgaactg     7680

cacggagttt tccttcattc ctgtcctggg accgagtcc                            7719


<210>  3890
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  3890
tgtgtttgca atggccatgc tgaagtgtgc aatataaaca atcctgaaaa actgtttcgg       60

tgtgaatgcc agcaccacac ctgtggggag acgtgtgatc gctgctgcac agggtacaat      120

cagaggcgct ggcggcccgc cgcttgggag cagagccacg agtgtgaagc atgcaactgc      180

cacggccatg ccagcaactg ttactatgat ccagatgttg agcggcagca ggcaagcttg      240

aatacccagg gcatctatgc tggtggaggg gtctgcatta actgtcagca caacacagct      300

ggagtaaact gtgaacagtg tgctaagggc tattaccgcc cttatggggt tccagtggat      360

gcccctgatg gctgcatccc ctgcagctgt gaccctgagc atgcggatgg ctgtgaacag      420

ggttcaggcc gctgtcactg caagccaaat ttccacggag acaactgtga gaagtgtgca      480

attggatact acaatttccc attttgcttg aga                                   513


<210>  3891
<211>  5295
<212>  DNA
<213>  Homo Sapiens

<400>  3891
caggaacccg agttcagcta cggctgcgca gaaggcagct gctatcccgc cacgggcgac       60

cttctcatcg gccgagcaca gaagctttcg gtgacctcga cgtgcgggct gcacaagccc      120

gaaccctact gtatcgtcag ccacttgcag gaggacaaaa aatgcttcat atgcaattcc      180

caagatcctt atcatgagac cctgaatcct gacagccatc tcattgaaaa tgtggtcact      240

acatttgctc caaaccgcct taagatttgg tggcaatctg aaaatggtgt ggaaaatgta      300

actatccaac tggatttgga agcagaattc cattttactc atctcataat gactttcaag      360

acattccgtc cagctgctat gctgatagaa cgatcgtccg actttgggaa aacctggggt      420

gtgtatagat acttcgccta tgactgtgag gcctcgtttc caggcatttc aactggcccc      480

atgaaaaaag tcgatgacat aatttgtgat tctcgatatt ctgacattga accctcaact      540

gaaggagagg tgatatttcg tgctttagat cctgctttca aaatagaaga tccttatagc      600

ccaaggatac agaatttatt aaaaattacc aacttgagaa tcaagtttgt gaaactgcat      660

actttgggag ataaccttct ggattccagg atggaaatca gagaaaagta ttattatgca      720

gtttatgata tggtggttcg aggaaattgc ttctgctatg gtcatgccag cgaatgtgcc      780

cctgtggatg gattcaatga agaagtggaa ggaatggttc acggacactg catgtgcagg      840

cataacacca agggcttaaa ctgtgaactc tgcatggatt tctaccatga tttaccttgg      900

agacctgctg aaggccgaaa cagcaacgcc tgtaaaaaat gtaactgcaa tgaacattcc      960

atctcttgtc actttgacat ggctgtttac ctggccacgg ggaacgtcag cggaggcgtg     1020

tgtgatgact gtcagcacaa caccatgggg cgcaactgtg agcagtgcaa gccgttttac     1080

taccagcacc cagagaggga catccgagat cctaatttct gtgaacgatg tacgtgtgac     1140

ccagctggct ctcaaaatga gggaatttgt gacagctata ctgatttttc tactggtctc     1200

attgctggcc agtgtcggtg taaattaaat gtggaaggag aacattgtga tgtttgcaaa     1260

gaaggcttct atgatttaag cagtgaagat ccatttggtt gtaaatcttg tgcttgcaat     1320

cctctgggaa caattcctgg agggaatcct tgtgattccg agacaggtca ctgctactgc     1380

aagcgtctgg tgacaggaca gcattgtgac cagtgcctgc cagagcactg gggcttaagc     1440

aatgatttgg atggatgtcg accatgtgac tgtgaccttg ggggagcctt aaacaacagt     1500

tgctttgcgg agtcaggcca gtgctcatgc cggcctcaca tgattggacg tcagtgcaac     1560

gaagtggaac ctggttacta ctttgccacc ctggatcact acctctatga agcggaggaa     1620

gccaacttgg ggcctggggt tagcatagtg gagcggcaat atatccagga ccggattccc     1680

tcctggactg gagccggctt cgtccgagtg cctgaagggg cttatttgga gtttttcatt     1740

gacaacatac catattccat ggagtacgac atcctaattc gctacgagcc acagctaccc     1800

gaccactggg aaaaagctgt catcacagtg cagcgacctg gaaggattcc aaccagcagc     1860

cgatgtggta ataccatccc cgatgatgac aaccaggtgg tgtcattatc accaggctca     1920

agatatgtcg tccttcctcg gccggtgtgc tttgagaagg gaacaaacta cacggtgagg     1980

ttggagctgc ctcagtacac ctcctctgat agcgacgtgg agagccccta cacgctgatc     2040

gattctcttg ttctcatgcc atactgtaaa tcactggaca tcttcaccgt gggaggttca     2100

ggagatgggg tggtcaccaa cagtgcctgg gaaacctttc agagataccg atgtctagag     2160

aacagcagaa gcgttgtgaa aacaccgatg acagatgttt gcagaaacat catctttagc     2220

atttctgccc tgttacacca gacaggcctg gcttgtgaat gcgaccctca gggttcgtta     2280

agttccgtgt gtgatcccaa cggaggccag tgccagtgcc ggcccaacgt ggttggaaga     2340

acctgcaaca gatgtgcacc tggaactttt ggctttggcc ccagtggatg caaaccttgt     2400

gagtgccatc tgcaaggatc tgtcaatgcc ttctgcaatc ccgtcactgg ccagtgccac     2460

tgtttccagg gagtgtatgc tcggcagtgt gatcggtgct tacctgggca ctggggcttt     2520

ccaagttgcc agccctgcca gtgcaatggc cacgccgatg actgcgaccc agtgactggg     2580

gagtgcttga actgccagga ctacaccatg ggtcataact gtgaaaggtg cttggctggt     2640

tactatggcg accccatcat tgggtcagga gatcactgcc gcccttgccc ttgcccagat     2700

ggtcccgaca gtggacgcca gtttgccagg agctgctacc aagatcctgt tactttacag     2760

cttgcctgtg tttgtgatcc tggatacatt ggttccagat gtgacgactg tgcctcagga     2820

tactttggca atccatcaga agttgggggg tcgtgtcagc cttgccagtg tcacaacaac     2880

attgacacga cagacccaga agcctgtgac aaggagactg ggaggtgtct caagtgcctg     2940

taccacacgg aaggggaaca ctgtcagttc tgccggtttg gatactatgg tgatgccctc     3000

cagcaggact gtcgaaagtg tgtctgtaat tacctgggca ccgtgcaaga gcactgtaac     3060

ggctctgact gccagtgcga caaagccact ggtcagtgct tgtgtcttcc taatgtgatc     3120

gggcagaact gtgaccgctg tgcgcccaat acctggcagc tggccagtgg cactggctgt     3180

gacccatgca actgcaatgc tgctcattcc ttcgggccat cttgcaatga gttcacgggg     3240

cagtgccagt gcatgcctgg gtttggaggc cgcacctgca gcgagtgcca ggaactcttc     3300

tggggagacc ccgacgtgga gtgccgagcc tgtgactgtg accccagggg cattgagacg     3360

ccacagtgtg accagtccac gggccagtgt gtctgcgttg agggtgttga gggtccacgc     3420

tgtgacaagt gcacgcgagg gtactcgggg gtcttccctg actgcacacc ctgccaccag     3480

tgctttgctc tctgggatgt gatcattgcc gagctgacca acaggacaca cagattcctg     3540

gagaaagcca aggccttgaa gatcagtggt gtgatcgggc cttaccgtga gactgtggac     3600

tcggtggaga ggaaagtcag cgagataaaa gacatcctgg cgcagagccc cgcagcagag     3660

ccactgaaaa acattgggaa tctctttgag gaagcagaga aactgattaa agatgttaca     3720

gaaatgatgg ctcaagtaga agtgaaatta tctgacacaa cttcccaaag caacagcaca     3780

gccaaagaac tggattctct acagacagaa gccgaaagcc tagacaacac tgtgaaagaa     3840

cttgctgaac aactggaatt tatcaaaaac tcagatattc ggggtgcctt ggatagcatt     3900

accaagtatt tccagatgtc tcttgaggca gaggagaggg tgaatgcctc caccacagaa     3960

cccaacagca ctgtggagca gtcagccctc atgagagaca gagtagaaga cgtgatgatg     4020

gagcgagaat cccagttcaa ggaaaaacaa gaggagcagg ctcgcctcct tgatgaactg     4080

gcaggcaagc tacaaagcct agacctttca gccgctgccg aaatgacctg tggaacaccc     4140

ccaggggcct cctgttccga gactgaatgt ggcgggccaa actgcagaac tgacgaagga     4200

gagaggaagt gtggggggcc tggctgtggt ggtctggtta ctgttgcaca caacgcctgg     4260

cagaaagcca tggacttgga ccaagatgtc ctgagtgccc tggctgaagt ggaacagctc     4320

tccaagatgg tctctgaagc aaaactgagg gcagatgagg caaaacaaag tgctgaagac     4380

attctgttga agacaaatgc taccaaagaa aaaatggaca agagcaatga ggagctgaga     4440

aatctaatca agcaaatcag aaactttttg acccaggata gtgctgattt ggacagcatt     4500

gaagcagttg ctaatgaagt attgaaaatg gagatgccta gcaccccaca gcagttacag     4560

aacttgacag aagatatacg tgaacgagtt gaaagccttt ctcaagtaga ggttattctt     4620

cagcatagtg ctgctgacat tgccagagct gagatgttgt tagaagaagc taaaagagca     4680

agcaaaagtg caacagatgt taaagtcact gcagatatgg taaaggaagc tctggaagaa     4740

gcagaaaagg cccaggtcgc agcagagaag gcaattaaac aagcagatga agacattcaa     4800

ggaacccaga acctgttaac ttcgattgag tctgaaacag cagcttctga ggaaaccttg     4860

ttcaacgcgt cccagcgcat cagcgagtta gagaggaatg tggaagaact taagcggaaa     4920

gctgcccaaa actccgggga ggcagaatat attgaaaaag tagtatatac tgtgaagcaa     4980

agtgcagaag atgttaagaa gactttagat ggtgaacttg atgaaaagta taaaaaagta     5040

gaaaatttaa ttgccaaaaa aactgaagag tcagctgatg ccagaaggaa agccgaaatg     5100

ctacaaaatg aagcaaaaac tcttttagct caagcaaata gcaagctgca actgctcaaa     5160

gatttagaaa gaaaatatga agacaatcaa agatacttag aagataaagc tcaagaatta     5220

gcaagactgg aaggagaagt ccgttcactc ctaaaggata taagccagaa agttgctgtg     5280

tatagcacat gcttg                                                      5295


<210>  3892
<211>  3465
<212>  DNA
<213>  Homo Sapiens

<400>  3892
caacaagcct gctcccgtgg ggcctgctat ccacctgttg gggacctgct tgttgggagg       60

acccggtttc tccgagcttc atctacctgt ggactgacca agcctgagac ctactgcacc      120

cagtatggcg agtggcagat gaaatgctgc aagtgtgact ccaggcagcc tcacaactac      180

tacagtcacc gagtagagaa tgtggcttca tcctccggcc ccatgcgctg gtggcagtcc      240

cagaatgatg tgaaccctgt ctctctgcag ctggacctgg acaggagatt ccagcttcaa      300

gaagtcatga tggagttcca ggggcccatg cctgccggca tgctgattga gcgctcctca      360

gacttcggta agacctggcg agtgtaccag tacctggctg ccgactgcac ctccaccttc      420

cctcgggtcc gccagggtcg gcctcagagc tggcaggatg ttcggtgcca gtccctgcct      480

cagaggccta atgcacgcct aaatgggggg aaggtccaac ttaaccttat ggatttagtg      540

tctgggattc cagcaactca aagtcaaaaa attcaagagg tgggggagat cacaaacttg      600

agagtcaatt tcaccaggct ggcccctgtg ccccaaaggg gctaccaccc tcccagcgcc      660

tactatgctg tgtcccagct ccgtctgcag gggagctgct tctgtcacgg ccatgctgat      720

cgctgcgcac ccaagcctgg ggcctctgca ggcccctcca ccgctgtgca ggtccacgat      780

gtctgtgtct gccagcacaa cactgccggc ccaaattgtg agcgctgtgc acccttctac      840

aacaaccggc cctggagacc ggcggagggc caggacgccc atgaatgcca aaggtgcgac      900

tgcaatgggc actcagagac atgtcacttt gaccccgctg tgtttgccgc cagccagggg      960

gcatatggag gtgtgtgtga caattgccgg gaccacaccg aaggcaagaa ctgtgagcgg     1020

tgtcagctgc actatttccg gaaccggcgc ccgggagctt ccattcagga gacctgcatc     1080

tcctgcgagt gtgatccgga tggggcagtg ccaggggctc cctgtgaccc agtgaccggg     1140

cagtgtgtgt gcaaggagca tgtgcaggga gagcgctgtg acctatgcaa gccgggcttc     1200

actggactca cctacgccaa cccgcagggc tgccaccgct gtgactgcaa catcctgggg     1260

tcccggaggg acatgccgtg tgacgaggag agtgggcgct gcctttgtct gcccaacgtg     1320

gtgggtccca aatgtgacca gtgtgctccc taccactgga agctggccag tggccagggc     1380

tgtgaaccgt gtgcctgcga cccgcacaac tccctcagcc cacagtgcaa ccagttcaca     1440

gggcagtgcc cctgtcggga aggctttggt ggcctgatgt gcagcgctgc agccatccgc     1500

cagtgtccag accggaccta tggagacgtg gccacaggat gccgagcctg tgactgtgat     1560

ttccggggaa cagagggccc gggctgcgac aaggcatcag gccgctgcct ctgccgccct     1620

ggcttgaccg ggccccgctg tgaccagtgc cagcgaggct actgcaatcg ctacccggtg     1680

tgcgtggcct gccacccttg cttccagacc tatgatgcgg acctccggga gcaggccctg     1740

cgctttggta gactccgcaa tgccaccgcc agcctgtggt cagggcctgg gctggaggac     1800

cgtggcctgg cctcccggat cctagatgca aagagtaaga ttgagcagat ccgagcagtt     1860

ctcagcagcc ccgcagtcac agagcaggag gtggctcagg tggccagtgc catcctctcc     1920

ctcaggcgaa ctctccaggg cctgcagctg gatctgcccc tggaggagga gacgttgtcc     1980

cttccgagag acctggagag tcttgacaga agcttcaatg gtctccttac tatgtatcag     2040

aggaagaggg agcagtttga aaaaataagc agtgctgatc cttcaggagc cttccggatg     2100

ctgagcacag cctacgagca gtcagcccag gctgctcagc aggtctccga cagctcgcgc     2160

cttttggacc agctcaggga cagccggaga gaggcagaga ggctggtgcg gcaggcggga     2220

ggaggaggag gcaccggcag ccccaagctt gtggccctga ggctggagat gtcttcgttg     2280

cctgacctga cacccacctt caacaagctc tgtggcaact ccaggcagat ggcttgcacc     2340

ccaatatcat gccctggtga gctatgtccc caagacaatg gcacagcctg tggctcccgc     2400

tgcaggggtg tccttcccag ggccggtggg gccttcttga tggcggggca ggtggctgag     2460

cagctgcggg gcttcaatgc ccagctccag cggaccaggc agatgattag ggcagccgag     2520

gaatctgcct cacagattca atccagtgcc cagcgcttgg agacccaggt gagcgccagc     2580

cgctcccaga tggaggaaga tgtcagacgc acacggctcc taatccagca ggtccgggac     2640

ttcctaacag accccgacac tgatgcagcc actatccagg aggtcagcga ggccgtgctg     2700

gccctgtggc tgcccacaga ctcagctact gttctgcaga agatgaatga gatccaggcc     2760

attgcagcca ggctccccaa cgtggacttg gtgctgtccc agaccaagca ggacattgcg     2820

cgtgcccgcc ggttgcaggc tgaggctgag gaagccagga gccgagccca tgcagtggag     2880

ggccaggtgg aagatgtggt tgggaacctg cggcagggga cagtggcact gcaggaagct     2940

caggacacca tgcaaggcac cagccgctcc cttcggctta tccaggacag ggttgctgag     3000

gttcagcagg tactgcggcc agcagaaaag ctggtgacaa gcatgaccaa gcagctgggt     3060

gacttctgga cacggatgga ggagctccgc caccaagccc ggcagcaggg ggcagaggca     3120

gtccaggccc agcagcttgc ggaaggtgcc agcgagcagg cattgagtgc ccaagaggga     3180

tttgagagaa taaaacaaaa gtatgctgag ttgaaggacc ggttgggtca gagttccatg     3240

ctgggtgagc agggtgcccg gatccagagt gtgaagacag aggcagagga gctgtttggg     3300

gagaccatgg agatgatgga caggatgaaa gacatggagt tggagctgct gcggggcagc     3360

caggccatca tgctgcgctc ggcggacctg acaggactgg agaagcgtgt ggagcagatc     3420

cgtgaccaca tcaatgggcg cgtgctctac tatgccacct gcaag                     3465


<210>  3893
<211>  5226
<212>  DNA
<213>  Homo Sapiens

<400>  3893
caagatgact gcaacagggg tgcctgtcat cccaccactg gtgatctcct ggtgggcagg       60

aacacgcagc ttatggcttc ttctacctgt gggctgagca gagcccagaa atactgcatc      120

ctcagttacc tggaggggga acaaaaatgc ttcatctgtg actctagatt tccatatgat      180

ccgtatgacc aacccaacag ccacaccatt gagaatgtca ttgtaagttt tgaaccagac      240

agagaaaaga aatggtggca atctgaaaat ggtcttgatc atgtcagcat cagactggac      300

ttagaggcat tatttcggtt cagccacctt atcctgacct ttaagacttt tcggcctgct      360

gcaatgttag ttgaacgttc cacagactat ggacacaact ggaaagtgtt caaatatttt      420

gcaaaagact gtgccacttc ctttcctaac atcacatctg gccaggccca gggagtggga      480

gacattgttt gtgactccaa atactcggat attgaaccct caacaggtgg agaggttgtt      540

ttaaaagttt tggatcccag ttttgaaatt gaaaaccctt atagccccta catccaagac      600

cttgtgacat tgacaaacct gaggataaac tttaccaagc tccacaccct tggggatgct      660

ttgcttggaa ggaggcaaaa tgattccctt gataaatact actatgctct gtacgagatg      720

attgttcggg gaagctgctt ttgcaatggc catgctagcg aatgtcgccc tatgcagaag      780

atgcggggag atgttttcag ccctcctgga atggttcacg gtcagtgtgt gtgtcagcac      840

aatacagatg gtccgaactg tgagagatgc aaggacttct tccaggatgc tccttggagg      900

ccagctgcag acctccagga caacgcttgc agatcgtgca gctgtaacag ccactccagc      960

cgctgtcact ttgacatgac tacgtacctg gcaagcggtg gcctcagcgg gggcgtgtgt     1020

gaagactgcc agcacaacac tgaggggcag cactgcgacc gctgcagacc cctcttctac     1080

agggacccgc tcaagaccat ctcagatccc tacgcgtgca ttccttgtga atgtgacccc     1140

gatgggacca tatctggtgg catttgtgtg agccactctg atcctgcctt agggtctgtg     1200

gctggccagt gcctttgtaa agagaacgtg gaaggagcca aatgcgacca gtgcaaaccc     1260

aaccactatg gactaagcgc caccgacccc ctgggctgcc agccctgcga ctgtaacccc     1320

cttgggagtc tgccattctt gacctgtgat gtggatacag gccaatgctt gtgcctgtca     1380

tatgtcaccg gagcacactg cgaagaatgc actgttggat actggggcct gggaaatcat     1440

ctccatgggt gttctccctg tgactgtgat attggaggtg cttattctaa cgtgtgctca     1500

cccaagaatg ggcagtgtga atgccgccca catgtcactg gccgtagctg ctctgaacca     1560

gcccctggct acttctttgc tcctttgaat ttctatctct acgaggcaga ggaagccaca     1620

acactccaag gactggcgcc tttgggctcg gagacgtttg gccagagtcc tgctgttcac     1680

gttgttttag gagagccagt tcctgggaac cctgttacat ggactggacc tggatttgcc     1740

agggttctcc ctggggctgg cttgagattt gctgtcaaca acattccctt tcctgtggac     1800

ttcaccattg ccattcacta tgaaacccag tctgcagctg actggactgt ccagattgtg     1860

gtgaaccccc ctggagggag tgagcactgc atacccaaga ctctacagtc aaagcctcag     1920

tcttttgcct taccagcggc tacgagaatc atgctgcttc ccacacccat ctgtttagaa     1980

ccagatgtac aatattccat agatgtctat ttttctcagc ctttgcaagg agagtcccac     2040

gctcattcac atgtcctggt ggactctctt ggccttattc cccaaatcaa ttcattggag     2100

aatttctgca gcaagcagga cttagatgag tatcagcttc acaactgtgt tgaaattgcc     2160

tcagcaatgg gacctcaagt gctcccgggt gcctgtgaaa ggctgatcat cagcatgtct     2220

gccaagctgc atgatggggc tgtggcctgc aagtgtcacc cccagggctc agtcggatcc     2280

agctgcagcc gacttggagg ccagtgccag tgtaaacctc ttgtggtcgg gcgctgctgt     2340

gacaggtgct caactggaag ctatgatttg gggcatcacg gctgtcaccc atgtcactgc     2400

catcctcaag gatcaaagga cactgtatgt gaccaagtaa caggacagtg cccctgccat     2460

ggagaggtgt ctggccgccg ctgtgatcgc tgcctggcag gctactttgg atttcccagc     2520

tgccaccctt gcccttgtaa taggtttgct gaactttgtg atcctgagac agggtcatgc     2580

ttcaattgtg gaggctttac aactggcaga aactgtgaaa ggtgtattga tggttactat     2640

ggaaatcctt cttcaggaca gccctgtcgt ccttgcctgt gtccagatga tccctcaagc     2700

aatcagtatt ttgcccattc ctgttatcag aatctgtgga gctcagatgt aatctgcaat     2760

tgtcttcaag gttatacggg tactcagtgt ggagaatgct ctactggttt ctatggaaat     2820

ccaagaattt caggagcacc ttgccaacca tgtgcctgca acaacaacat agatgtaacc     2880

gatccagagt cctgcagccg ggtaacaggg gagtgccttc gatgtttgca caacactcag     2940

ggcgcaaact gccagctctg caaaccaggt cactatggat cagccctcaa tcagacctgc     3000

agaagatgct cctgccatgc ttccggcgtg agtcccatgg agtgtccccc tggtggggga     3060

gcttgcctct gtgaccctgt cactggtgca tgtccttgtc tgccgaatgt cacaggcctg     3120

gcctgtgacc gttgtgctga tggatactgg aatctggtcc ctggcagagg atgtcagtca     3180

tgtgactgtg accctaggac ctctcaaagt agccactgtg accagcttac aggccagtgt     3240

ccgtgtaaat taggttacgg cgggaaacgt tgcagtgagt gccaggaaaa ttattatggt     3300

gatccacctg ggcgatgcat tccatgtgat tgtaacaggg caggtaccca gaagcccatc     3360

tgtgatccag acacaggcat gtgccgctgc cgggagggtg tcagcggcca gagatgtgat     3420

cgctgtgccc ggggacacag ccaggaattc cctacttgtc ttcaatgtca cttgtgcttt     3480

gatcagtggg accacaccat ttcttccctc tccaaagcgg tgcaagggtt aatgagactg     3540

gctgctaaca tggaagataa aagagagacc ctgcctgtct gtgaggcaga cttcaaagac     3600

ctcagaggga acgtgtctga aatagaaagg attttgaaac atcctgtttt cccatctggg     3660

aaattcttaa aagtcaagga ttatcatgac tctgttagaa gacaaatcat gcagctaaat     3720

gaacaactga aagcagtgta tgaatttcaa gatctgaaag atacaataga aagagcaaag     3780

aatgaagcag acctcttact tgaagacctt caggaagaaa ttgatttgca atccagtgtc     3840

cttaatgcaa gcattgcgga ctcctcagaa aacatcaaga aatattatca catatcatca     3900

tctgctgaaa agaaaattaa tgaaactagt tccaccatta atacctctgc aaatacaagg     3960

aatgacttac ttaccatctt agatacacta acctcaaaag gaaacttgtc attggaaaga     4020

ttaaagcaga ttaagatacc agatatccaa atattgaatg aaaaggtgtg cggagatcca     4080

ggaaatgtgc catgtgtgcc cttgccctgt ggcggtgctc tctgcacggg ccggaagggg     4140

cacaggaagt gtaggggtcc cggctgtcac ggctccctga ccctctcaac gaatgccctc     4200

caaaaagccc aggaagcaaa atccattatt cgtaatttgg acaaacaggt tcgtgggttg     4260

aaaaatcaga tcgaaagtat aagtgaacag gcagaagtct ccaaaaacaa tgccttacag     4320

ctgagggaaa aactgggaaa tataagaaac caaagtgact ctgaagaaga aaacatcaat     4380

cttttcatca aaaaagtgaa aaactttttg ttagaggaaa acgtgcctcc agaagacatc     4440

gagaaggttg cgaatggtgt gcttgacatt cacctaccaa ttccatccca aaatctaacc     4500

gatgaacttg tcaaaataca gaaacatatg caactctgtg aggattacag gacagatgaa     4560

aacaggttaa atgaagaagc agatggagcc caaaagcttt tggtgaaggc caaagcagct     4620

gagaaagcag caaatattct attaaatctt gacaaaacat tgaaccagtt acaacaagct     4680

caaatcactc aaggacgggc aaactctacc attacacagc tgactgccaa tataacaaaa     4740

ataaaaaaga atgtgctgca ggctgaaaat caaaccaggg aaatgaagag tgagctggag     4800

ttagcaaagc agcgatcagg gctggaggat ggactttccc tgctgcagac caagttgcaa     4860

aggcatcaag accacgctgt caatgcgaaa gttcaggctg aatctgccca acaccaggct     4920

gggagtcttg agaaggaatt tgttgagctg aaaaaacaat atgctattct ccaacgtaag     4980

acaagcacta caggactaac aaaggagaca ttaggaaaag ttaaacagct aaaagatgcg     5040

gcagaaaaat tggctggaga tacagaggcc aagataagaa gaataacaga tttagaaagg     5100

aaaatccaag atttgaatct aagtagacaa gcaaaagctg atcaactgag aatattggaa     5160

gatcaagttg ttgccattaa aaatgaaatt gttgaacaag aaaaaaaata tgctaggtgc     5220

tatagc                                                                5226


<210>  3894
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  3894
caggcagcca tggacgagtg cacggacgag ggcgggcggc cgcagcgctg catgcccgag       60

ttcgtcaacg ccgctttcaa cgtgactgtg gtggccacca acacgtgtgg gactccgccc      120

gaggaatact gtgtgcagac cggggtgacc ggggtcacca agtcctgtca cctgtgcgac      180

gccgggcagc cccacctgca gcacggggca gccttcctga ccgactacaa caaccaggcc      240

gacaccacct ggtggcaaag ccagaccatg ctggccgggg tgcagtaccc cagctccatc      300

aacctcacgc tgcacctggg aaaagctttt gacatcacct atgtgcgtct caagttccac      360

accagccgcc cggagagctt tgccatttac aagcgcacac gggaagacgg gccctggatt      420

ccttaccagt actacagtgg ttcctgcgag aacacctact ccaaggcaaa ccgcggcttc      480

atcaggacag gaggggacga gcagcaggcc ttgtgtactg atgaattcag tgacatttct      540

cccctcactg ggggcaacgt ggccttttct accctggaag gaaggcccag cgcctataac      600

tttgacaata gccctgtgct gcaggtaaat tctcacaggt tggcc                      645


<210>  3895
<211>  3270
<212>  DNA
<213>  Homo Sapiens

<400>  3895
acctccagga gggaagtctg tgattgcaat gggaagtcca ggcagtgtat ctttgatcgg       60

gaacttcaca gacaaactgg taatggattc cgctgcctca actgcaatga caacactgat      120

ggcattcact gcgagaagtg caagaatggc ttttaccggc acagagaaag ggaccgctgt      180

ttgccctgca attgtaactc caaaggttct cttagtgctc gatgtgacaa ctccggacgg      240

tgcagctgta aaccaggtgt gacaggagcc agatgcgacc gatgtctgcc aggcttccac      300

atgctcacgg atgcggggtg cacccaagac cagagactgc tagactccaa gtgtgactgt      360

gacccagctg gcatcgcagg gccctgtgac gcgggccgct gtgtctgcaa gccagctgtc      420

actggagaac gctgtgatag gtgtcgatca ggttactata atctggatgg ggggaaccct      480

gagggctgta cccagtgttt ctgctatggg cattcagcca gctgccgcag ctctgcagaa      540

tacagtgtcc ataagatcac ctctaccttt catcaagatg ttgatggctg gaaggctgtc      600

caacgaaatg ggtctcctgc aaagctccaa tggtcacagc gccatcaaga tgtgtttagc      660

tcagcccaac gactagaccc tgtctatttt gtggctcctg ccaaatttct tgggaatcaa      720

caggtgagct atggtcaaag cctgtccttt gactaccgtg tggacagagg aggcagacac      780

ccatctgccc atgatgtgat tctggaaggt gctggtctac ggatcacagc tcccttgatg      840

ccacttggca agacactgcc ttgtgggctc accaagactt acacattcag gttaaatgag      900

catccaagca ataattggag cccccagctg agttactttg agtatcgaag gttactgcgg      960

aatctcacag ccctccgcat ccgagctaca tatggagaat acagtactgg gtacattgac     1020

aatgtgaccc tgatttcagc ccgccctgtc tctggagccc cagcaccctg ggttgaacag     1080

tgtatatgtc ctgttgggta caaggggcaa ttctgccagg attgtgcttc tggctacaag     1140

agagattcag cgagactggg gccttttggc acctgtattc cttgtaactg tcaaggggga     1200

ggggcctgtg atccagacac aggagattgt tattcagggg atgagaatcc tgacattgag     1260

tgtgctgact gcccaattgg tttctacaac gatccgcacg acccccgcag ctgcaagcca     1320

tgtccctgtc ataacgggtt cagctgctca gtgatgccgg agacggagga ggtggtgtgc     1380

aataactgcc ctcccggggt caccggtgcc cgctgtgagc tctgtgctga tggctacttt     1440

ggggacccct ttggtgaaca tggcccagtg aggccttgtc agccctgtca atgcaacaac     1500

aatgtggacc ccagtgcctc tgggaattgt gaccggctga caggcaggtg tttgaagtgt     1560

atccacaaca cagccggcat ctactgcgac cagtgcaaag caggctactt cggggaccca     1620

ttggctccca acccagcaga caagtgtcga gcttgcaact gtaaccccat gggctcagag     1680

cctgtaggat gtcgaagtga tggcacctgt gtttgcaagc caggatttgg tggccccaac     1740

tgtgagcatg gagcattcag ctgtccagct tgctataatc aagtgaagat tcagatggat     1800

cagtttatgc agcagcttca gagaatggag gccctgattt caaaggctca gggtggtgat     1860

ggagtagtac ctgatacaga gctggaaggc aggatgcagc aggctgagca ggcccttcag     1920

gacattctga gagatgccca gatttcagaa ggtgctagca gatcccttgg tctccagttg     1980

gccaaggtga ggagccaaga gaacagctac cagagccgcc tggatgacct caagatgact     2040

gtggaaagag ttcgggctct gggaagtcag taccagaacc gagttcggga tactcacagg     2100

ctcatcactc agatgcagct gagcctggca gaaagtgaag cttccttggg aaacactaac     2160

attcctgcct cagaccacta cgtggggcca aatggcttta aaagtctggc tcaggaggcc     2220

acaagattag cagaaagcca cgttgagtca gccagtaaca tggagcaact gacaagggaa     2280

actgaggact attccaaaca agccctctca ctggtgcgca aggccctgca tgaaggagtc     2340

ggaagcggaa gcggtagccc ggacggtgct gtggtgcaag ggcttgtgga aaaattggag     2400

aaaaccaagt ccctggccca gcagttgaca agggaggcca ctcaagcgga aattgaagca     2460

gataggtctt atcagcacag tctccgcctc ctggattcag tgtctcggct tcagggagtc     2520

agtgatcagt cctttcaggt ggaagaagca aagaggatca aacaaaaagc ggattcactc     2580

tcaagcctgg taaccaggca tatggatgag ttcaagcgta cacagaagaa tctgggaaac     2640

tggaaagaag aagcacagca gctcttacag aatggaaaaa gtgggagaga gaaatcagat     2700

cagctgcttt cccgtgccaa tcttgctaaa agcagagcac aagaagcact gagtatgggc     2760

aatgccactt tttatgaagt tgagagcatc cttaaaaacc tcagagagtt tgacctgcag     2820

gtggacaaca gaaaagcaga agctgaagaa gccatgaaga gactctccta catcagccag     2880

aaggtttcag atgccagtga caagacccag caagcagaaa gagccctggg gagcgctgct     2940

gctgatgcac agagggcaaa gaatggggcc ggggaggccc tggaaatctc cagtgagatt     3000

gaacaggaga ttgggagtct gaacttggaa gccaatgtga cagcagatgg agccttggcc     3060

atggaaaagg gactggcctc tctgaagagt gagatgaggg aagtggaagg agagctggaa     3120

aggaaggagc tggagtttga cacgaatatg gatgcagtac agatggtgat tacagaagcc     3180

cagaaggttg ataccagagc caagaacgct ggggttacaa tccaagacac actcaacaca     3240

ttagacggcc tcctgcatct gatgggtatg                                      3270


<210>  3896
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  3896
gcgacgggtc gcctgctgag tgggcagcca gtctgccggg gagggacaca gaggccttgt       60

tataaagtca tttacttcca tgatacttct cgaagactga actttgagga agccaaagaa      120

gcctgcagga gggatggagg ccagctagtc agcatcgagt ctgaagatga acagaaactg      180

atagaaaagt tcattgaaaa cctcttgcca tctgatggtg acttctggat tgggctcagg      240

aggcgtgagg agaaacaaag caatagcaca gcctgccagg acctttatgc ttggactgat      300

ggcagcatat cacaatttag gaactggtat gtggatgagc cgtcctgcgg cagcgaggtc      360

tgcgtggtca tgtaccatca gccatcggca cccgctggca tcggaggccc ctacatgttc      420

cagtggaatg atgaccggtg caacatgaag aacaatttca tttgcaaata ttctgatgag      480

aaaccagcag ttccttctag agaagctgaa ggtgaggaaa cagagctgac aacacctgta      540

cttccagaag aaacacagga agaagatgcc aaaaaaacat ttaaagaaag tagagaagct      600

gccttgaatc tggcctac                                                    618


<210>  3897
<211>  2301
<212>  DNA
<213>  Homo Sapiens

<400>  3897
gcagtgggcg acagatgtga aagaaacgag ttccagtgcc aagacgggaa atgcatctcc       60

tacaagtggg tctgcgatgg cagcgctgag tgccaggatg gctctgatga gtcccaggag      120

acgtgcttgt ctgtcacctg caaatccggg gacttcagct gtgggggccg tgtcaaccgc      180

tgcattcctc agttctggag gtgcgatggc caagtggact gcgacaacgg ctcagacgag      240

caaggctgtc cccccaagac gtgctcccag gacgagtttc gctgccacga tgggaagtgc      300

atctctcggc agttcgtctg tgactcagac cgggactgct tggacggctc agacgaggcc      360

tcctgcccgg tgctcacctg tggtcccgcc agcttccagt gcaacagctc cacctgcatc      420

ccccagctgt gggcctgcga caacgacccc gactgcgaag atggctcgga tgagtggccg      480

cagcgctgta ggggtcttta cgtgttccaa ggggacagta gcccctgctc ggccttcgag      540

ttccactgcc taagtggcga gtgcatccac tccagctggc gctgtgatgg tggccccgac      600

tgcaaggaca aatctgacga ggaaaactgc gctgtggcca cctgtcgccc tgacgaattc      660

cagtgctctg atggaaactg catccatggc agccggcagt gtgaccggga atatgactgc      720

aaggacatga gcgatgaagt tggctgcgtt aatgtgacac tctgcgaggg acccaacaag      780

ttcaagtgtc acagcggcga atgcatcacc ctggacaaag tctgcaacat ggctagagac      840

tgccgggact ggtcagatga acccatcaaa gagtgcggga ccaacgaatg cttggacaac      900

aacggcggct gttcccacgt ctgcaatgac cttaagatcg gctacgagtg cctgtgcccc      960

gacggcttcc agctggtggc ccagcgaaga tgcgaagata tcgatgagtg tcaggatccc     1020

gacacctgca gccagctctg cgtgaacctg gagggtggct acaagtgcca gtgtgaggaa     1080

ggcttccagc tggaccccca cacgaaggcc tgcaaggctg tgggctccat cgcctacctc     1140

ttcttcacca accggcacga ggtcaggaag atgacgctgg accggagcga gtacaccagc     1200

ctcatcccca acctgaggaa cgtggtcgct ctggacacgg aggtggccag caatagaatc     1260

tactggtctg acctgtccca gagaatgatc tgcagcaccc agcttgacag agcccacggc     1320

gtctcttcct atgacaccgt catcagcagg gacatccagg cccccgacgg gctggctgtg     1380

gactggatcc acagcaacat ctactggacc gactctgtcc tgggcactgt ctctgttgcg     1440

gataccaagg gcgtgaagag gaaaacgtta ttcagggaga acggctccaa gccaagggcc     1500

atcgtggtgg atcctgttca tggcttcatg tactggactg actggggaac tcccgccaag     1560

atcaagaaag ggggcctgaa tggtgtggac atctactcgc tggtgactga aaacattcag     1620

tggcccaatg gcatcaccct agatctcctc agtggccgcc tctactgggt tgactccaaa     1680

cttcactcca tctcaagcat cgatgtcaat gggggcaacc ggaagaccat cttggaggat     1740

gaaaagaggc tggcccaccc cttctccttg gccgtctttg aggacaaagt attttggaca     1800

gatatcatca acgaagccat tttcagtgcc aaccgcctca caggttccga tgtcaacttg     1860

ttggctgaaa acctactgtc cccagaggat atggtcctct tccacaacct cacccagcca     1920

agaggagtga actggtgtga gaggaccacc ctgagcaatg gcggctgcca gtatctgtgc     1980

ctccctgccc cgcagatcaa cccccactcg cccaagttta cctgcgcctg cccggacggc     2040

atgctgctgg ccagggacat gaggagctgc ctcacagagg ctgaggctgc agtggccacc     2100

caggagacat ccaccgtcag gctaaaggtc agctccacag ccgtaaggac acagcacaca     2160

accacccggc ctgttcccga cacctcccgg ctgcctgggg ccacccctgg gctcaccacg     2220

gtggagatag tgacaatgtc tcaccaagct ctgggcgacg ttgctggcag aggaaatgag     2280

aagaagccca gtagcgtgag g                                               2301


<210>  3898
<211>  1839
<212>  DNA
<213>  Homo Sapiens

<400>  3898
tttaacttgt catatccaat tactccttgg agatttaagt tgtcttgcat gccaccaaat       60

tcaacctatg actacttcct tttgcctgct ggactctcaa agaatacttc aaattcgaat      120

ggacattatg agacagctgt tgaacctaag tttaattcaa gtggtactca cttttctaac      180

ttatccaaaa caactttcca ctgttgcttt cggagtgagc aagatagaaa ctgctcctta      240

tgtgcagaca acattgaagg aaagacattt gtttcaacag taaattcttt agtttttcaa      300

caaatagatg caaactggaa catacagtgc tggctaaaag gagacttaaa attattcatc      360

tgttatgtgg agtcattatt taagaatcta ttcaggaatt ataactataa ggtccatctt      420

ttatatgttc tgcctgaagt gttagaagat tcacctctgg ttccccaaaa aggcagtttt      480

cagatggttc actgcaattg cagtgttcat gaatgttgtg aatgtcttgt gcctgtgcca      540

acagccaaac tcaacgacac tctccttatg tgtttgaaaa tcacatctgg tggagtaatt      600

ttccagtcac ctctaatgtc agttcagccc ataaatatgg tgaagcctga tccaccatta      660

ggtttgcata tggaaatcac agatgatggt aatttaaaga tttcttggtc cagcccacca      720

ttggtaccat ttccacttca atatcaagtg aaatattcag agaattctac aacagttatc      780

agagaagctg acaagattgt ctcagctaca tccctgctag tagacagtat acttcctggg      840

tcttcgtatg aggttcaggt gaggggcaag agactggatg gcccaggaat ctggagtgac      900

tggagtactc ctcgtgtctt taccacacaa gatgtcatat actttccacc taaaattctg      960

acaagtgttg ggtctaatgt ttcttttcac tgcatctata agaaggaaaa caagattgtt     1020

ccctcaaaag agattgtttg gtggatgaat ttagctgaga aaattcctca aagccagtat     1080

gatgttgtga gtgataatgt tagcaaagtt acttttttca atctgaatga aaccaaacct     1140

cgaggaaagt ttacctatga tgcagtgtac tgctgcaatg aacatgaatg ccatcatcgc     1200

tatgctgaat tatatgtgat tgatgtcaat atcaatatct catgtgaaac tgatgggtac     1260

ttaactaaaa tgacttgcag atggtcaacc agtacaatcc agtcacttgc ggaaagcact     1320

ttgcaattga ggtatcatag gagcagcctt tactgttctg atattccatc tattcatccc     1380

atatctgagc ccaaagattg ctatttgcag agtgatggtt tttatgaatg cattttccag     1440

ccaatcttcc tattatctgg ctacacaatg tggattagga tcaatcactc tctaggttca     1500

cttgactctc caccaacatg tgtccttcct gattctgtgg tgaagccact gcctccatcc     1560

agtgtgaaag cagaaattac tataaacatt ggattattga aaatatcttg ggaaaagcca     1620

gtctttccag agaataacct tcaattccag attcgctatg gtttaagtgg aaaagaagta     1680

caatggaaga tgtatgaggt ttatgatgca aaatcaaaat ctgtcagtct cccagttcca     1740

gacttgtgtg cagtctatgc tgttcaggtg cgctgtaaga ggctagatgg actgggatat     1800

tggagtaatt ggagcaatcc agcctacaca gttgtcatg                            1839


<210>  3899
<211>  1569
<212>  DNA
<213>  Homo Sapiens

<400>  3899
aagaaaccag cgaagccaaa atgccctgcc gtgtgtactt gtaccaaaga taatgcttta       60

tgtgagaatg ccagatccat tccacgcacc gttcctcctg atgttatctc attatccttt      120

gtgagatctg gttttactga aatctcagaa gggagttttt tattcacgcc atcgctgcag      180

ctcttgttat tcacatcgaa ctcctttgat gtgatcagtg atgatgcttt tattggtctt      240

ccacatctag agtatttatt catagaaaac aacaacatca agtcaatttc aagacatact      300

ttccggggac taaagtcatt aattcacttg agccttgcaa acaacaatct ccagacactc      360

ccaaaagata ttttcaaagg cctggattct ttaacaaatg tggacctgag gggtaattca      420

tttaattgtg actgtaaact gaaatggcta gtggaatggc ttggccacac caatgcaact      480

gttgaagaca tctactgcga aggcccccca gaatacaaga agcgcaaaat caatagtctc      540

tcctcgaagg atttcgattg catcattaca gaatttgcaa agtctcaaga cctgccttat      600

caatcattgt ccatagacac tttttcttat ttgaatgatg agtatgtagt catcgctcag      660

ccttttactg gaaaatgcat tttccttgaa tgggaccatg tggaaaagac cttccggaat      720

tatgacaaca ttacaggcac atccactgta gtatgcaagc ctatagtcat tgaaactcag      780

ctctatgtta ttgtggccca gctgtttggt ggctctcaca tctataagcg agacagtttt      840

gcaaataaat tcataaaaat ccaggatatt gaaattctca aaatccgaaa acccaatgac      900

attgaaacat tcaagattga aaacaactgg tactttgttg ttgctgacag ttcaaaagct      960

ggttttacta ccatttacaa atggaacgga aacggattct actcccatca atccttacac     1020

gcgtggtaca gggacactga tgtggaatat ctagaaatag tcagaacacc tcagacactc     1080

agaacgcctc atttaattct gtctagtagt tcccagcgtc ctgtaattta tcagtggaac     1140

aaagcaacac aattattcac taaccaaact gacattccta acatggagga tgtgtacgca     1200

gtgaagcact tctcagtgaa aggggacgtg tacatttgct tgacaagatt cattggtgat     1260

tccaaagtca tgaaatgggg aggctcctcg ttccaggata ttcagaggat gccatcgcga     1320

ggatccatgg tgttccagcc tcttcaaata aataattacc aatatgcaat tcttggaagt     1380

gattactcct ttactcaagt gtataactgg gatgcagaga aagccaaatt tgtgaaattt     1440

caggaattaa atgttcaggc accaagatca ttcacacatg tgtccattaa taagcgtaat     1500

tttctttttg cttccagttt taagggaaat acacagattt acaaacatgt catagttgac     1560

ttaagcgca                                                             1569


<210>  3900
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  3900
caggtgaggc ggctggcgcg ctgccccgcc acttgcagct gtaccaagga gtctatcatc       60

tgcgtgggct cttcctgggt gcccaggatc gtgccgggcg acatcagctc cctgagcctg      120

gtaaatggga cgttttcaga aatcaaggac cgaatgtttt cccatctgcc ttctctgcag      180

ctgctattgc tgaattctaa ctcattcacg atcatccggg atgatgcttt tgctggactt      240

tttcatcttg aatacctgtt cattgaaggg aacaaaatag aaaccatttc aagaaatgcc      300

tttcgtggcc tccgtgacct gactcacctt tctttggcca ataaccacat aaaagcacta      360

ccaagggatg tcttcagtga tttagactct ctgattgaac tagatttgag gggtaataaa      420

tttgaatgtg actgcaaagc caagtggcta tacctgtggt tgaagatgac aaattccacc      480

gtttctgatg tgctgtgtat tggtccacca gagtatcagg aaaagaagct aaatgacgtg      540

accagctttg actatgaatg cacaactaca gattttgttg ttcatcagac tttaccctac      600

cagtcggttt cagtggatac gttcaactcc aagaacgatg tgtacgtggc catcgcgcag      660

cccagcatgg agaactgcat ggtgctggag tgggaccaca ttgaaatgaa tttccggagc      720

tatgacaaca ttacaggtca gtccatcgtg ggctgtaagg ccattctcat cgatgatcag      780

gtctttgtgg tggtagccca gctcttcggt ggctctcaca tttacaaata cgacgagagt      840

tggaccaaat ttgtcaaatt ccaagacata gaggtctctc gcatttccaa gcccaatgac      900

atcgagctgt ttcagatcga cgacgagacg ttctttgtca tcgcagacag ctcaaaggct      960

ggtctgtcca cagtttataa atggaacagc aaaggattct attcttacca gtcactgcac     1020

gagtggttca gggacacgga tgcggagttt gttgatatcg atggaaaatc gcatctcatc     1080

ctgtccagcc gctcccaggt ccccatcatc ctccagtgga ataaaagctc taagaagttt     1140

gtcccccatg gtgacatccc caacatggag gacgtactgg ctgtgaagag cttccgaatg     1200

caaaataccc tctacctttc ccttacccgc ttcatcgggg actcccgggt catgaggtgg     1260

aacagtaagc agtttgtgga gatccaagct cttccatccc ggggggccat gaccctgcag     1320

cccttttctt ttaaagataa tcactacctg gccctgggga gtgactatac attctctcag     1380

atataccagt gggataaaga gaagcagcta ttcaaaaagt ttaaggagat ttatgtgcag     1440

gcgcctcgtt cattcacagc tgtctccacc gacaggagag atttcttttt tgcatccagt     1500

ttcaaaggga aaacaaagat ttttgaacat ataattgttg acttaagttt g              1551


<210>  3901
<211>  1554
<212>  DNA
<213>  Homo Sapiens

<400>  3901
aagaggcccc cgaagactcc cccttgcccg ccatcctgtt catgtactag ggatactgcg       60

ttctgcgttg atagcaaggc cgtaccaaga aacttgccga gcgaagttat cagcttgacg      120

cttgtaaacg ctgcgttctc cgaaatacaa gatggagctt ttagtcattt acctctgttg      180

cagtttttac tactaaatag taacaaattc actcttatag gagataatgc tttcaccggg      240

ttatcacacc ttcagtatct gttcattgaa aacaacgaca tctgggcctt atcaaagttc      300

actttcagag gcttaaagag ccttacgcat ctgtcactgg cgaacaataa tctacagact      360

ttgccaaggg acatcttccg tcctttggac atccttaatg accttgatct gagaggaaat      420

tcattaaact gcgattgcaa ggtgaaatgg cttgtggagt ggcttgctca cacaaacacc      480

acggtcgccc ctatatattg tgcttctcct cctcgtttcc aggaacacaa agtacaggat      540

ctgcccttaa gagagtttga ttgcattacc acggacttcg tgttgtacca gaccctagcg      600

tttcccgcgg taagtgcgga gccattcctg tacagctccg atctatattt ggcattagca      660

caacccggtg tatccgcctg tactatatta aaatgggatt acgtggaacg tcagctaaga      720

gattatgaca gaataccggc tccatcagcg gtacattgta aaccgatggt agttgatagc      780

cagctgtatg tcgtagtagc gcagcttttt ggaggaagct atatctatca ctgggacccc      840

aacactaccc gtttcacgag actgcaggac atcgaccctc agagggtcag gaagcctaat      900

gatttagaag ctttcagaat agacggtgac tggtactttg ccgtcgcaga tagtagtaag      960

gcaggggcga cgtccctata cagatggcac cagaatggat tctactcaca ccaggcttta     1020

cacccttggc atcgtgacac agacttggag tttgtggacg gcgagggtaa acccaggctg     1080

attgttagca gttcatctca agccccagtt atataccagt ggtcaagaac tcagaagcag     1140

tttgttgctc aaggtgaggt tacccaggtc ccggatgctc aagctgtcaa acatttccgt     1200

gcaggcaggg attcctactt atgcctaagt agatacatag gggactctaa gatcctaagg     1260

tgggagggca ccagattttc cgaagttcag gccctgccct caagaggctc cttggcctta     1320

cagccctttt tggtcggtgg gagaaggtat ctagcactag gaagcgactt cagctttaca     1380

caaatctacc agtgggatga aggacgtcaa aaattcgtca gattccaaga gctagcagtg     1440

caagcaccgc gtgctttttg ttatatgccc gccggcgatg cacagcttct gctagctcct     1500

tctttcaaag gtcagacctt ggtctatagg cacatagtag ttgacttgag cgcc           1554


<210>  3902
<211>  1554
<212>  DNA
<213>  Homo Sapiens

<400>  3902
tggagacccc caaagggaaa gtgtcccctg cgctgctcct gctctaaaga cagcgccctg       60

tgtgagggct ccccggacct gcccgtcagc ttctctccga ccctgctgtc actctcactc      120

gtcaggacgg gagtcaccca gctgaaggcc ggcagcttcc tgagaattcc gtctctgcac      180

ctgctcctct tcacctccaa ctccttctcc gtgattgagg acgatgcatt tgcgggcctg      240

tcccacctgc agtacctctt catcgaggac aatgagattg gctccatctc taagaatgcc      300

ctcagaggac ttcgctcgct tacacaccta agcctggcca ataaccatct ggagaccctc      360

cccagattcc tgttccgagg cctggacacc cttactcacg tggacctccg cgggaacccg      420

ttccagtgtg actgccgcgt cctctggctc ctgcagtgga tgcccaccgt gaatgccagc      480

gtggggaccg gcgcctgtgc gggccccgcc tccctgagcc acatgcagct ccaccacctc      540

gaccccaaga ctttcaagtg cagagccata gagctgtcct ggttccagac ggtgggggag      600

tcggcactga gcgtagagcc cttctcctac caaggggagc ctcacattgt gctggcacag      660

cccttcgccg gccgctgcct gattctctcc tgggactaca gcctgcagcg cttccggccc      720

gaggaagagc tgcccgcggc ctccgtggtg tcctgcaagc cactggtgct gggcccgagc      780

ctcttcgtgc tggctgcccg cctgtggggg ggctcacagc tgtgggcccg gcccagtccc      840

ggcctgcgcc tggccccaac gcagaccctg gccccgcggc ggctgctgcg gcccaatgac      900

gccgagctcc tgtggctgga agggcaaccc tgcttcgtgg tggccgatgc ctccaaggcg      960

ggcagcacca cgctgctgtg ccgcgacggg cccggctttt acccgcacca gagcctgcac     1020

gcctggcacc gggacacgga cgctgaggcc ctggagctgg acggccggcc ccacctgctg     1080

ctggcctcgg cttcccagcg gcccgtgctc ttccactgga ccggtggccg cttcgagaga     1140

cgcacagaca tccccgaggc cgaggatgtc tatgccacac gccacttcca ggctggtggg     1200

gacgtgttcc tgtgcctcac acgctacatt ggggactcca tggtcatgcg ctgggacggc     1260

tccatgtttc gtctgctgca gcaacttccc tcgcgcggtg cccacgtctt ccagccactg     1320

ctcatcgcca gggaccagct ggccatccta ggcagcgact tcgccttcag ccaggtcctc     1380

cgccttgagc ctgacaaggg gctcctggag ccactgcagg agctggggcc tccggccctg     1440

gtggcccccc gtgcctttgc ccacatcact atggccggca gacgcttcct ctttgctgct     1500

tgctttaagg gccccacaca gatctaccag catcacgaga tcgacctcag tgcc           1554


<210>  3903
<211>  1560
<212>  DNA
<213>  Homo Sapiens

<400>  3903
gcgccgcctc tctgcgcggc gccctgcagc tgcgacggcg accgtcgggt ggactgctcc       60

gggaaggggc tgacggccgt gcccgagggg ctcagcgcct tcacccaagc gctggatatc      120

agtatgaaca acattactca gttgccagaa gatgcattta agaactttcc ttttctagaa      180

gagctacaat tggcgggcaa cgacctttct tttatccacc caaaggcctt gtctgggttg      240

aaagaactca aagttctaac gctccagaat aatcagttga aaacagtacc cagtgaagcc      300

attcgagggc tgagtgcttt gcagtctttg cgtttagatg ccaaccatat tacctcagtc      360

cccgaggaca gttttgaagg acttgttcag ttacggcatc tgtggctgga tgacaacagc      420

ttgacggagg tgcctgtgca ccccctcagc aatctgccca ccctacaggc gctgaccctg      480

gctctcaaca agatctcaag catccctgac tttgcattta ccaacctttc aagcctggta      540

gttctgcatc ttcataacaa taaaattaga ggcctgagtc aacactgttt tgatggacta      600

gataacctgg agaccttaga cttgagttat aataacttgg gggaatttcc tcaggctatt      660

aaagcccgtc ctagccttaa agagctagga tttcatagta attctatttc tgttatccct      720

gatggagcat ttgatggtaa tccactctta agaactatac atttgtatga taatcctctg      780

tcttttgtgg ggaactcagc atctcacaat ttatctgatc ttcattccct agtcattcgt      840

ggtgcaagca tggtgcagca gttccccaat cttacaggaa ctgtccacct ggaaagtctg      900

actttgacag gtacaaagat aagcagcata cctaataatt tgtgtcaaga acaaaagatg      960

cttaggactt tggacttgtc ttacaataat ataagagacc ttccaagttt taatggttgc     1020

catgctctgg aagaaatttc tttacagcgt aatcaaatct accaaataaa ggaaggcacc     1080

tttcaaggcc tgatatctct aaggattcta gatctgagta gaaacctgat acatgaaatt     1140

cacagtagag cttttgccac acttgggcca ataactaacc tagatgtaag tttcaatgaa     1200

ttaacttcct ttcctacgga aggcccgaat gggctaaatc aactgaaact tgtgggcaac     1260

ttcaagctga aagaagcctt agcagcaaaa gactttgtta acctcaggtc tttatcggta     1320

ccatatgctt atcagtgctg tgcattttgg ggttgtgact cttatgcaaa tttaaacaca     1380

gaagataaca gcctccagga ccacagtgtg gcacaggaga aaggtactgc tgatgcagca     1440

aatgtcacaa gcactcttga aaatgaagaa catagtcaaa taattatcca ttgtacacct     1500

tcaacaggtg cttttaagcc ctgtgaatat ttactgggaa gctggatgat tcgtcttact     1560


<210>  3904
<211>  1620
<212>  DNA
<213>  Homo Sapiens

<400>  3904
ggcagctctc ccaggtctgg tgtgttgctg aggggctgcc ccacacactg tcattgcgag       60

cccgacggca ggatgttgct cagggtggac tgctccgacc tggggctctc ggagctgcct      120

tccaacctca gcgtcttcac ctcctaccta gacctcagta tgaacaacat cagtcagctg      180

ctcccgaatc ccctgcccag tctccgcttc ctggaggagt tacgtcttgc gggaaacgct      240

ctgacataca ttcccaaggg agcattcact ggcctttaca gtcttaaagt tcttatgctg      300

cagaataatc agctaagaca cgtacccaca gaagctctgc agaatttgcg aagccttcaa      360

tccctgcgtc tggatgctaa ccacatcagc tatgtgcccc caagctgttt cagtggcctg      420

cattccctga ggcacctgtg gctggatgac aatgcgttaa cagaaatccc cgtccaggct      480

tttagaagtt tatcggcatt gcaagccatg accttggccc tgaacaaaat acaccacata      540

ccagactatg cctttggaaa cctctccagc ttggtagttc tacatctcca taacaataga      600

atccactccc tgggaaagaa atgctttgat gggctccaca gcctagagac tttagattta      660

aattacaata accttgatga attccccact gcaattagga cactctccaa ccttaaagaa      720

ctaggatttc atagcaacaa tatcaggtcg atacctgaga aagcatttgt aggcaaccct      780

tctcttatta caatacattt ctatgacaat cccatccaat ttgttgggag atctgctttt      840

caacatttac ctgaactaag aacactgact ctgaatggtg cctcacaaat aactgaattt      900

cctgatttaa ctggaactgc aaacctggag agtctgactt taactggagc acagatctca      960

tctcttcctc aaaccgtctg caatcagtta cctaatctcc aagtgctaga tctgtcttac     1020

aacctattag aagatttacc cagtttttca gtctgccaaa agcttcagaa aattgaccta     1080

agacataatg aaatctacga aattaaagtt gacactttcc agcagttgct tagcctccga     1140

tcgctgaatt tggcttggaa caaaattgct attattcacc ccaatgcatt ttccactttg     1200

ccatccctaa taaagctgga cctatcgtcc aacctcctgt cgtcttttcc tataactggg     1260

ttacatggtt taactcactt aaaattaaca ggaaatcatg ccttacagag cttgatatca     1320

tctgaaaact ttccagaact caaggttata gaaatgcctt atgcttacca gtgctgtgca     1380

tttggagtgt gtgagaatgc ctataagatt tctaatcaat ggaataaagg tgacaacagc     1440

agtatggacg accttcataa gaaagatgct ggaatgtttc aggctcaaga tgaacgtgac     1500

cttgaagatt tcctgcttga ctttgaggaa gacctgaaag cccttcattc agtgcagtgt     1560

tcaccttccc caggcccctt caaaccctgt gaacacctgc ttgatggctg gctgatcaga     1620


<210>  3905
<211>  1629
<212>  DNA
<213>  Homo Sapiens

<400>  3905
gcgccgcaac caggtcccgg tcctacggcc tgtccggccc cgtgccattg ccaggaagac       60

ggtattatgt tgtctgcgga ttgttctgaa ttagggttat ctgccgttcc cggagattta      120

gacccactta ctgcatacct tgacttgagt atgaataacc tgacagagct gcaaccgggt      180

ctatttcatc acttaagatt cctagaagag cttagactaa gcggaaatca cctgagtcat      240

attcctggtc aagcgtttag cggcctttac tcattaaaaa ttctgatgct tcagaacaat      300

caattgggag gtatcccggc cgaagcctta tgggaattac ccagcctgca gtctctgaga      360

ttagatgcga atctaataag cctagttccg gaacgttctt tcgaaggttt gagctcactg      420

aggcacctgt ggcttgatga taacgctctg accgagatcc ccgtgagagc attgaacaac      480

ttgccagctc ttcaggccat gaccctagcg ctgaatcgta tcagtcatat tcctgactat      540

gcattccaaa atttaaccag tctagtggtg cttcacttgc acaacaatcg tattcaacat      600

ttaggaacac atagctttga gggtctgcac aatctggaaa cattggatct gaactataat      660

aagctacagg agtttccagt ggcgattaga accctgggga ggttgcaaga gttgggtttc      720

cacaacaaca atataaaggc aatccccgag aaagcgttca tgggtaaccc tctactgcag      780

accatccact tctacgataa tccgatacaa ttcgtggggc gttcagcttt ccagtatcta      840

cccaaattac acacgctttc tcttaatggt gccatggata ttcaagagtt cccggatttg      900

aagggcacaa ccagcctaga gattctgact ctgacgagag caggaataag gttactgcca      960

tcaggaatgt gtcaacaact gcccaggtta agggttttag aacttagcca caaccagatt     1020

gaggaacttc cttcacttca taggtgccag aaactagagg aaatcggatt gcaacataac     1080

cgtatttggg agataggggc cgataccttt tcccagctaa gttccttaca ggctttggac     1140

ttatcatgga acgcgatcag atctatacat ccggaggcct tttccaccct acatagtcta     1200

gttaaactgg atttaaccga taatcagcta acgactttgc ctttggcagg tctgggcggc     1260

ctaatgcacc taaagctgaa aggaaatctg gccttatcac aggccttttc caaggattca     1320

ttcccgaaac tgaggatcct agaagtgcca tatgcctacc aatgctgtcc ttatggcatg     1380

tgtgcctcat tcttcaaggc ctccggccag tgggaagccg aagaccttca tcttgacgac     1440

gaagagtcaa gcaagagacc cttagggttg ctggctagac aggcggaaaa ccactatgac     1500

caagacctag atgaactgca gttagaaatg gaagactcca agccgcaccc ttcagttcag     1560

tgctcaccga ccccggggcc tttcaagccc tgcgagtact tgttcgagtc ctgggggatc     1620

agactagct                                                             1629


<210>  3906
<211>  1248
<212>  DNA
<213>  Homo Sapiens

<400>  3906
atgattgttt ttctggtttt taaacatctc ttcagcctca gattgattac aatgttcttt       60

ctacttcatt tcatcgttct gatcaatgtc aaagattttg cactgactca aggtagcatg      120

atcactcctt catgccaaaa aggatatttt ccctgtggga atcttaccaa gtgcttaccc      180

cgagcttttc actgtgatgg caaggatgac tgtgggaacg gggcggacga agagaactgt      240

ggtgacacta gtggatgggc gaccatattt ggcacagtgc atggaaatgc taacagcgtg      300

gccttaacac aggagtgctt tctaaaacag tatccacaat gctgtgactg caaagaaact      360

gaattggaat gtgtaaatgg tgacttaaag tctgtgccga tgatttctaa caatgtgaca      420

ttactgtctc ttaagaaaaa caaaatccac agtcttccag ataaagtttt catcaaatac      480

acaaaactta aaaagatatt tcttcagcat aattgcatta gacacatatc caggaaagca      540

ttttttggat tatgtaatct gcaaatatta tatctcaacc acaactgcat cacaaccctc      600

agacctggaa tattcaaaga cttacatcag ctaacttggc taattctaga tgacaatcca      660

ataaccagaa tttcacagcg cttgtttacg ggattaaatt ccttgttttt cctgtctatg      720

gttaataact acttagaagc tcttcccaag cagatgtgtg cccaaatgcc tcaactcaac      780

tgggtggatt tggaaggcaa tagaataaag tatctcacaa attctacgtt tctgtcgtgc      840

gattcgctca cagtgctgtt tctgcctaga aatcaaattg gttttgttcc agagaagaca      900

ttttcttcat taaaaaattt aggagaactg gatctgtcta gcaatacgat aacggaacta      960

tcacctcacc tttttaaaga cttgaagctt ctacaaaagc tgaacctgtc atccaatcct     1020

cttatgtatc ttcacaagaa ccagtttgaa agtcttaaac aacttcagtc tctagacctg     1080

gaaaggatag agattccaaa tataaacaca cgaatgtttc aacccatgaa gaatctttct     1140

cacatttatt tcaaaaactt tcgatactgc tcctatgctc cccatgtccg aatatgtatg     1200

cccttgacgg acggcatttc ttcatttgag gacctcttgg ctaacaat                  1248


<210>  3907
<211>  1011
<212>  DNA
<213>  Homo Sapiens

<400>  3907
gaggcgctct gccctgagcc ctgcaactgc gtgcccgacg gcgccctgcg ctgccccggc       60

cccacggccg gtctcactcg actatcactt gcctacctcc ctgtcaaagt gatcccatct      120

caagctttca gaggacttaa tgaggtcata aaaattgaaa tctctcagat tgattccctg      180

gaaaggatag aagctaatgc ctttgacaac ctcctcaatt tgtctgaaat actgatccag      240

aacaccaaaa atctgagata cattgagccc ggagcattta taaatcttcc ccgattaaaa      300

tacttgagca tctgtaacac aggcatcaga aagtttccag atgttacgaa ggtcttctcc      360

tctgaatcaa atttcattct ggaaatttgt gataacttac acataaccac cataccagga      420

aatgcttttc aagggatgaa taatgaatct gtaacactca aactatatgg aaatggattt      480

gaagaagtac aaagtcatgc attcaatggg acgacactga cttcactgga gctaaaggaa      540

aacgtacatc tggagaagat gcacaatgga gccttccgtg gggccacagg gccgaaaacc      600

ttggatattt cttccaccaa attgcaggcc ctgccgagct atggcctaga gtccattcag      660

aggctaattg ccacgtcatc ctattctcta aaaaaattgc catcaagaga aacatttgtc      720

aatctcctgg aggccacgtt gacttacccc agccactgct gtgcttttag aaacttgcca      780

acaaaagaac agaatttttc acattccatt tctgaaaact tttccaaaca atgtgaaagc      840

acagtaagga aagtgaataa caaaacactt tattcttcca tgcttgctga gagtgaactg      900

agtggctggg actatgaata tggtttctgc ttacccaaga caccccgatg tgctcctgaa      960

ccagatgctt ttaatccctg tgaagatatt atgggctatg acttccttag g              1011


<210>  3908
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  3908
agccccctcc ccatcacccc tgtcaacgcc acctgtgcca tacgccaccc atgtcacaac       60

aacctcatga accagatcag gagccaactg gcacagctca atggcagtgc caatgccctc      120

tttattctct attacacagc ccagggggag ccgttcccca acaacctgga caagctatgt      180

ggccccaacg tgacggactt cccgcccttc cacgccaacg gcacggagaa ggccaagctg      240

gtggagctgt accgcatagt cgtgtacctt ggcacctccc tgggcaacat cacccgggac      300

cagaagatcc tcaaccccag tgccctcagc ctccacagca agctcaacgc caccgccgac      360

atcctgcgag gcctccttag caacgtgctg tgccgcctgt gcagcaagta ccacgtgggc      420

catgtggacg tgacctacgg ccctgacacc tcgggtaagg atgtcttcca gaagaagaag      480

ctgggctgtc aactcctggg gaagtataag cagatcatcg ccgtgttggc ccaggccttc      540


<210>  3909
<211>  2367
<212>  DNA
<213>  Homo Sapiens

<400>  3909
cagaaaaagg gggctcctca tgatttgaag tgtgtaacta acaatttgca agtgtggaac       60

tgttcttgga aagcaccctc tggaacaggc cgtggtactg attatgaagt ttgcattgaa      120

aacaggtccc gttcttgtta tcagttggag aaaaccagta ttaaaattcc agctctttca      180

catggtgatt atgaaataac aataaattct ctacatgatt ttggaagttc tacaagtaaa      240

ttcacactaa atgaacaaaa cgtttcctta attccagata ctccagagat cttgaatttg      300

tctgctgatt tctcaacctc tacattatac ctaaagtgga acgacagggg ttcagttttt      360

ccacaccgct caaatgttat ctgggaaatt aaagttctac gtaaagagag tatggagctc      420

gtaaaattag tgacccacaa cacaactctg aatggcaaag atacacttca tcactggagt      480

tgggcctcag atatgccctt ggaatgtgcc attcattttg tggaaattag atgctacatt      540

gacaatcttc atttttctgg tctcgaagag tggagtgact ggagccctgt gaagaacatt      600

tcttggatac ctgattctca gactaaggtt tttcctcaag ataaagtgat acttgtaggc      660

tcagacataa cattttgttg tgtgagtcaa gaaaaagtgt tatcagcact gattggccat      720

acaaactgcc ccttgatcca tcttgatggg gaaaatgttg caatcaagat tcgtaatatt      780

tctgtttctg caagtagtgg aacaaatgta gtttttacaa ccgaagataa catatttgga      840

accgttattt ttgctggata tccaccagat actcctcaac aactgaattg tgagacacat      900

gatttaaaag aaattatatg tagttggaat ccaggaaggg tgacagcgtt ggtgggccca      960

cgtgctacaa gctacacttt agttgaaagt ttttcaggaa aatatgttag acttaaaaga     1020

gctgaagcac ctacaaacga aagctatcaa ttattatttc aaatgcttcc aaatcaagaa     1080

atatataatt ttactttgaa tgctcacaat ccgctgggtc gatcacaatc aacaatttta     1140

gttaatataa ctgaaaaagt ttatccccat actcctactt cattcaaagt gaaggatatt     1200

aattcaacag ctgttaaact ttcttggcat ttaccaggca actttgcaaa gattaatttt     1260

ttatgtgaaa ttgaaattaa gaaatctaat tcagtacaag agcagcggaa tgtcacaatc     1320

aaaggagtag aaaattcaag ttatcttgtt gctctggaca agttaaatcc atacactcta     1380

tatacttttc ggattcgttg ttctactgaa actttctgga aatggagcaa atggagcaat     1440

aaaaaacaac atttaacaac agaagccagt ccttcaaagg ggcctgatac ttggagagag     1500

tggagttctg atggaaaaaa tttaataatc tattggaagc ctttacccat taatgaagct     1560

aatggaaaaa tactttccta caatgtatcg tgttcatcag atgaggaaac acagtccctt     1620

tctgaaatcc ctgatcctca gcacaaagca gagatacgac ttgataagaa tgactacatc     1680

atcagcgtag tggctaaaaa ttctgtgggc tcatcaccac cttccaaaat agcgagtatg     1740

gaaattccaa atgatgatct caaaatagaa caagttgttg ggatgggaaa ggggattctc     1800

ctcacctggc attacgaccc caacatgact tgcgactacg tcattaagtg gtgtaactcg     1860

tctcggtcgg aaccatgcct tatggactgg agaaaagttc cctcaaacag cactgaaact     1920

gtaatagaat ctgatgagtt tcgaccaggt ataagatata attttttcct gtatggatgc     1980

agaaatcaag gatatcaatt attacgctcc atgattggat atatagaaga attggctccc     2040

attgttgcac caaattttac tgttgaggat acttctgcag attcgatatt agtaaaatgg     2100

gaagacattc ctgtggaaga acttagaggc tttttaagag gatatttgtt ttactttgga     2160

aaaggagaaa gagacacatc taagatgagg gttttagaat caggtcgttc tgacataaaa     2220

gttaagaata ttactgacat atcccagaag acactgagaa ttgctgatct tcaaggtaaa     2280

acaagttacc acctggtctt gcgagcctat acagatggtg gagtgggccc ggagaagagt     2340

atgtatgtgg tgacaaagga aaattct                                         2367


<210>  3910
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  3910
ccccggaccc acgtgcaggc agggaccctc cccaagccca cactctgggc tgagccaggc       60

tctgtgatca cccaggggag tcccgtgacc ctctggtgtc aggggatcct ggagacccag      120

gagtaccgtc tgtatagaga aaagaaaaca gcaccctgga ttacacggat cccacaggag      180

attgtgaaga agggccagtt ccccatccca tccatcacct gggaacacac agggcggtat      240

cgctgtttct acggtagcca cactgcaggc tggtcagagc ccagtgaccc cctggagctg      300

gtggtgacag gagcctacat caaacccacc ctctcagctc tacccagccc tgtggtgacc      360

tcaggaggga acgtgaccct ccattgtgtc tcacaggtgg catttggcag cttcattctg      420

tgtaaggaag gagaagatga acacccacaa tgcctgaact cacagccccg tacccatggg      480

tggtcccggg ccatcttctc tgtgggcccc gtgagcccga gtcgcaggtg gtcgtacagg      540

tgctatgctt atgactcgaa ctctccccat gtgtggtctc tacccagtga tctcctggag      600

ctcctggtcc taggtgtttc taagaagcca tcactctcag tgcagccagg tcctatagtg      660

gcccctgggg agagcctgac cctccagtgt gtttctgatg tcagctacga cagatttgtt      720

ctgtataagg agggagaacg tgacttcctc cagctccctg gcccacagcc ccaggctggg      780

ctctcccagg ccaacttcac cctgggccct gtgagccgct cctacggggg ccagtacaga      840

tgctccggtg catacaacct ctcctccgag tggtcggccc ccagcgaccc cctggacatc      900

ctgatcgcag gacagttccg tggcagaccc ttcatctcgg tgcatccggg ccccacggtg      960

gcctcaggag agaacgtgac cctgctgtgt cagtcatggg ggccgttcca cactttcctt     1020

ctgaccaagg cgggagcagc tgatgccccc ctccgtctca gatcaataca cgaatatcct     1080

aagtaccagg ctgaattccc tatgagtcct gtgacctcag cccactcggg gacctacagg     1140

tgctacggct cactcagctc caacccctac ctgctgtctc accccagtga ctccctggag     1200

ctcatggtct caggagcagc tgagaccctc agcccaccac aaaacaagtc cgattccaag     1260

gctggagcag ctaacaccct cagcccatca caaaacaaga ctgcctcaca cccccaggat     1320

tacacagtgg agaat                                                      1335


<210>  3911
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  3911
gggcacctcc ccaagcccac cctctgggct gagccaggct ctgtgatcat ccagggaagt       60

cctgtgaccc tcaggtgtca ggggagcctt caggctgagg agtaccatct atatagggaa      120

aacaaatcag catcctgggt tagacggata caagagcctg ggaagaatgg ccagttcccc      180

atcccatcca tcacctggga acacgcaggg cggtatcact gtcagtacta cagccacaat      240

cactcatcag agtacagtga ccccctggag ctggtggtga caggagccta cagcaaaccc      300

accctctcag ctctgcccag ccctgtggtg accttaggag ggaacgtgac cctccagtgt      360

gtctcacagg tggcatttga cggcttcatt ctgtgtaagg aaggagaaga tgaacaccca      420

caacgcctga actcccattc ccatgcccgt gggtggtcct gggccatctt ctccgtgggc      480

cccgtgagcc cgagtcgcag gtggtcgtac aggtgctatg cttatgactc gaactctccc      540

tatgtgtggt ctctacccag tgatctcctg gagctcctgg tcccaggtgt ttctaagaag      600

ccatcactct cagtgcagcc aggtcctatg gtggcccctg gggagagcct gaccctccag      660

tgtgtctctg atgtcggcta cgacagattt gttctgtata aggagggaga acgtgacttc      720

ctccagcgcc ctggttggca gccccaggct gggctctccc aggccaactt caccctgggc      780

cctgtgagcc cctcccacgg gggccagtac agatgctaca gtgcacacaa cctctcctcc      840

gagtggtcgg cccccagtga ccccctggac atcctgatca caggacagtt ctatgacaga      900

ccctctctct cggtgcagcc ggtccccaca gtagccccag gaaagaacgt gaccctgctg      960

tgtcagtcac gggggcagtt ccacactttc cttctgacca aggagggggc aggccatccc     1020

ccactgcatc tgagatcaga gcaccaagct cagcagaacc aggctgaatt ccgcatgggt     1080

cctgtgacct cagcccacgt ggggacctac agatgctaca gctcactcag ctccaacccc     1140

tacctgctgt ctctccccag tgaccccctg gagctcgtgg tctcagcatc cctaggccaa     1200

cacccccagg attacacagt ggagaat                                         1227


<210>  3912
<211>  1248
<212>  DNA
<213>  Homo Sapiens

<400>  3912
gggcccctcc ccaagcccac cctctgggct gagccaggct ctgtgatcac ccaagggagt       60

cctgtgaccc tcaggtgtca ggggagcctg gagacgcagg agtaccatct atatagagaa      120

aagaaaacag cactctggat tacacggatc ccacaggagc ttgtgaagaa gggccagttc      180

cccatcctat ccatcacctg ggaacatgca gggcggtatt gctgtatcta tggcagccac      240

actgtaggcc tctcagagag cagtgacccc ctggagctgg tggtgacagg agcctacagc      300

aaacccaccc tctcagctct gcccagccct gtggtgacct caggagggaa tgtgaccatc      360

cagtgtgact cacaggtggc atttgatggc ttcattctgt gtaaggaagg agaagatgaa      420

cacccacaat gcctgaactc ccattcccat gcccgtgggt catcccgggc catcttctcc      480

gtgggccccg tgagcccaag tcgcaggtgg tcgtacaggt gctatggtta tgactcgcgc      540

gctccctatg tgtggtctct acccagtgat ctcctggggc tcctggtccc aggtgtttct      600

aagaagccat cactctcagt gcagccgggt cctgtcgtgg cccctgggga gaagctgacc      660

ttccagtgtg gctctgatgc cggctacgac agatttgttc tgtacaagga gtggggacgt      720

gacttcctcc agcgccctgg ccggcagccc caggctgggc tctcccaggc caacttcacc      780

ctgggccctg tgagccgctc ctacgggggc cagtacacat gctccggtgc atacaacctc      840

tcctccgagt ggtcggcccc cagcgacccc ctggacatcc tgatcacagg acagatccgt      900

gccagaccct tcctctccgt gcggccgggc cccacagtgg cctcaggaga gaacgtgacc      960

ctgctgtgtc agtcacaggg agggatgcac actttccttt tgaccaagga gggggcagct     1020

gattccccgc tgcgtctaaa atcaaagcgc caatctcata agtaccaggc tgaattcccc     1080

atgagtcctg tgacctcggc ccacgcgggg acctacaggt gctacggctc actcagctcc     1140

aacccctacc tgctgactca ccccagtgac cccctggagc tcgtggtctc aggagcagct     1200

gagaccctca gcccaccaca aaacaagtcc gactccaagg ctggtgag                  1248


<210>  3913
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  3913
gaaaacctac ccaaacccat cctgtgggcc gagccaggtc ccgtgatcac ctggcataac       60

cccgtgacca tctggtgtca gggcaccctg gaggcccagg ggtaccgtct ggataaagag      120

ggaaactcaa tgtcgaggca catattaaaa acactggagt ctgaaaacaa ggtcaaactc      180

tccatcccat ccatgatgtg ggaacatgca gggcgatatc actgttacta tcagagccct      240

gcaggctggt cagagcccag cgaccccctg gagctggtgg tgacagccta cagcagaccc      300

accctgtccg ccctgccaag ccctgtggta acctcaggag tgaacgtgac cctccggtgt      360

gcctcacggc tgggactggg caggttcact ctgattgagg aaggagacca caggctctcc      420

tggaccctga actcacacca acacaaccat ggaaagttcc aggccctgtt ccccatgggc      480

cccctgacct tcagcaacag gggtacattc agatgctacg gctatgaaaa caacacccca      540

tacgtgtggt cggaacccag tgaccccctg cagctactgg tgtcaggcgt gtctaggaag      600

ccctccctcc tgaccctgca gggccctgtc gtgacccccg gagagaatct gaccctccag      660

tgtggctctg atgtcggcta catcagatac actctgtaca aggagggggc cgatggcctc      720

ccccagcgcc ctggccggca gccccaggct gggctctccc aggccaactt caccctgagc      780

cctgtgagcc gctcctacgg gggccagtac agatgctacg gcgcacacaa cgtctcctcc      840

gagtggtcgg cccccagtga ccccctggac atcctgatcg caggacagat ctctgacaga      900

ccctccctct cagtgcagcc gggccccacg gtgacctcag gagagaaggt gaccctgctg      960

tgtcagtcat gggacccgat gttcactttc cttctgacca aggagggggc agcccatccc     1020

ccgttgcgtc tgagatcaat gtacggagct cataagtacc aggctgaatt ccccatgagt     1080

cctgtgacct cagcccacgc ggggacctac aggtgctacg gctcacgcag ctccaacccc     1140

tacctgctgt ctcaccccag tgagcccctg gagctcgtgg tctcaggagc aactgagacc     1200

ctcaatccag cacaaaagaa gtcagattcc aagactgccc cacacctcca ggattacaca     1260

gtggagaat                                                             1269


<210>  3914
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  3914
ggaaatttat ctaaggctac tctatgggcg gaaccgggga gtgtcatcag caggggaaac       60

tccgtaacta tccgttgcca aggtactctg gaggcgcaag agtatagact ggtgaaagag      120

gggtcacccg aaccctggga tactcaaaat cctctggaac ctaagaacaa agcaagattt      180

agcattccta gtatgacaga gcatcatgca gggagatata ggtgctatta ctactcaccc      240

gcaggttggt ctgaacccag tgacccctta gagctagtag tcaccgggtt ttacaacaaa      300

cccactcttt ctgcattacc gtcccccgtg gttacttctg gcgagaacgt cactttacag      360

tgcgggtcca gactaagatt tgaccgtttc attttgacgg aggagggtga tcacaagttg      420

agctggactc tggatagtca gttgaccccg tccgggcagt ttcaggcgct tttccccgtt      480

gggccagtaa cgcccagcca tagatggatg cttcgttgtt atggcagtcg tcgtcacatc      540

cttcaagtgt ggtctgaacc ttccgatttg ttagagatcc ccgttagtgg agctgctgat      600

aatctatcac catctcagaa taagagcgat agcggtaccg cgtcacactt gcaggactat      660

gccgtagaga acttaatcag a                                                681


<210>  3915
<211>  1314
<212>  DNA
<213>  Homo Sapiens

<400>  3915
gggcacctcc ccaagcccac cctctgggct gaaccaggct ctgtgatcac ccaggggagt       60

cctgtgaccc tcaggtgtca ggggggccag gagacccagg agtaccgtct atatagagaa      120

aagaaaacag caccctggat tacacggatc ccacaggagc ttgtgaagaa gggccagttc      180

cccatcccat ccatcacctg ggaacatgca gggcggtatc gctgttacta tggtagcgac      240

actgcaggcc gctcagagag cagtgacccc ctggagctgg tggtgacagg agcctacatc      300

aaacccaccc tctcagccca gcccagcccc gtggtgaact caggagggaa tgtaaccctc      360

cagtgtgact cacaggtggc atttgatggc ttcattctgt gtaaggaagg agaagatgaa      420

cacccacaat gcctgaactc ccagccccat gcccgtgggt cgtcccgcgc catcttctcc      480

gtgggccccg tgagcccgag tcgcaggtgg tggtacaggt gctatgctta tgactcgaac      540

tctccctatg agtggtctct acccagtgat ctcctggagc tcctggtcct aggtgtttct      600

aagaagccat cactctcagt gcagccaggt cctatcgtgg cccctgagga gaccctgact      660

ctgcagtgtg gctctgatgc tggctacaac agatttgttc tgtataagga cggggaacgt      720

gacttccttc agctcgctgg cgcacagccc caggctgggc tctcccaggc caacttcacc      780

ctgggccctg tgagccgctc ctacgggggc cagtacagat gctacggtgc acacaacctc      840

tcctccgagt ggtcggcccc cagcgacccc ctggacatcc tgatcgcagg acagttctat      900

gacagagtct ccctctcggt gcagccgggc cccacggtgg cctcaggaga gaacgtgacc      960

ctgctgtgtc agtcacaggg atggatgcaa actttccttc tgaccaagga gggggcagct     1020

gatgacccat ggcgtctaag atcaacgtac caatctcaaa aataccaggc tgaattcccc     1080

atgggtcctg tgacctcagc ccatgcgggg acctacaggt gctacggctc acagagctcc     1140

aaaccctacc tgctgactca ccccagtgac cccctggagc tcgtggtctc aggaccgtct     1200

gggggcccca gctccccgac aacaggcccc acctccacat ctggccctga ggaccagccc     1260

ctcaccccca ccgggtcgga tccccagagt ggtctgggaa ggcacctggg ggtt           1314


<210>  3916
<211>  1320
<212>  DNA
<213>  Homo Sapiens

<400>  3916
cagacaggga ccatccccaa gcccaccctg tgggctgagc cagactctgt gatcacccag       60

gggagtcccg tcaccctcag ttgtcagggg agccttgaag cccaggagta ccgtctatat      120

agggagaaaa aatcagcatc ttggattaca cggatacgac cagagcttgt gaagaacggc      180

cagttccaca tcccatccat cacctgggaa cacacagggc gatatggctg tcagtattac      240

agccgcgctc ggtggtctga gctcagtgac cccctggtgc tggtgatgac aggagcctac      300

ccaaaaccca ccctctcagc ccagcccagc cctgtggtga cctcaggagg aagggtgacc      360

ctccagtgtg agtcacaggt ggcatttggc ggcttcattc tgtgtaagga aggagaagat      420

gaacacccac aatgcctgaa ctcccagccc catgcccgtg ggtcgtcccg cgccatcttc      480

tccgtgggcc ccgtgagccc gaatcgcagg tggtcgcaca ggtgctatgg ttatgacttg      540

aactctccct atgtgtggtc ttcacccagt gatctcctgg agctcctggt cccaggtgtt      600

tctaagaagc catcactctc agtgcagccg ggtcctgtcg tggcccctgg ggaaagcctg      660

accctccagt gtgtctctga tgtcggctat gacagatttg ttctgtacaa ggagggggaa      720

cgtgaccttc gccagctccc tggccggcag ccccaggctg ggctctccca ggccaacttc      780

accctgggcc ctgtgagccg ctcctacggg ggccagtaca gatgctacgg tgcatacaac      840

ctctcctccg agtggtcggc ccccagcgac cccctggaca tcctgatcac aggacagatc      900

catggcacac ccttcatctc agtgcagcca ggccccacag tggcctcagg agagaacgtg      960

accctgctgt gtcagtcatg gcggcagttc cacactttcc ttctgaccaa ggcgggagca     1020

gctgatgccc cactccgtct aagatcaata cacgaatatc ctaagtacca ggctgaattc     1080

cccatgagtc ctgtgacctc agcccacgcg gggacctaca ggtgctacgg ctcactcaac     1140

tccgacccct acctgctgtc tcaccccagt gagcccctgg agctcgtggt ctcaggaccc     1200

tccatgggtt ccagcccccc acccaccggt cccatctcca cacctgcagg ccctgaggac     1260

cagcccctca cccccactgg gtcggatccc caaagtggtc tgggaaggca cctgggggtt     1320


<210>  3917
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3917
ggacctttcc caaaacctac tctttgggca gagccggggt cagtaataag ttgggggagc       60

cccgtgacca tttggtgtca gggatctcaa gaggcgcagg agtatcgttt acacaaagag      120

ggaagtcctg aaccattaga tcgtaataac ccactggagc ctaagaacaa ggccaggttc      180

tccatcccta gcatgacgga acaccatgcc ggaagatatc gttgccacta ttactcatca      240

gcgggttggt cagaaccgtc agatccgcta gaaatggtta tgacaggcgc ttattccaaa      300

ccgacactaa gcgccctgcc cagtccggtg gttgcatcag gtgggaatat gactctacgt      360

tgtggtagcc agaagggata tcaccatttt gtgttgatga aggaaggcga gcatcagcta      420

ccaaggacat tggatagcca gcaacttcat agtagagggt tccaggcctt attccctgtt      480

gggccagtca ccccatcaca tagatggaga ttcacgtgtt actactacta cacgaacacc      540

ccgtgggtgt ggtcacaccc atccgatccg ttagagatcc taccctcagg agtatctcgt      600

aagccatcac tattaacgct tcaggggccg gtgctagctc ccggacagtc actgacatta      660

caatgcggta gcgacgtggg ttacaatagg ttcgttcttt acaaagaggg cgaaagagac      720

tttttgcaga gaccgggcca gcaacctcag gcgggattaa gccaggctaa tttcacctta      780

ggcccggtat cccctagtaa cggcggacag tatcgttgct acggtgctca caacctgtca      840

tcagagtggt ccgcaccaag tgacccgttg aacattctta tggcgggaca aatttacgat      900

acggttagtc tttccgcgca gcccggcccg actgttgcgt caggggagaa tgttacgtta      960

ctgtgtcagt cctggtggca attcgacacg ttccttttga ccaaggaagg tgcggcgcat     1020

cctccattac gtctgagatc aatgtacggt gctcataaat accaagccga atttcctatg     1080

agtccggtga cctctgcaca tgctggcacg tacaggtgtt atgggagcta cagttccaac     1140

ccgcaccttc ttagtcaccc ttcagaaccg cttgagctag tcgtgtccgg acatagcgga     1200

ggttctagtt tgccacccac ggggccgcct agtaccccgg gccttggcag atatctggag     1260


<210>  3918
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  3918
caggcagggc ccctccccaa acccaccctc tgggctgagc caggctctgt gatcagctgg       60

gggaactctg tgaccatctg gtgtcagggg accctggagg ctcgggagta ccgtctggat      120

aaagaggaaa gcccagcacc ctgggacaga cagaacccac tggagcccaa gaacaaggcc      180

agattctcca tcccatccat gacagaggac tatgcaggga gataccgctg ttactatcgc      240

agccctgtag gctggtcaca gcccagtgac cccctggagc tggtgatgac aggagcctac      300

agtaaaccca ccctttcagc cctgccgagt cctcttgtga cctcaggaaa gagcgtgacc      360

ctgctgtgtc agtcacggag cccaatggac actttccttc tgatcaagga gcgggcagcc      420

catcccctac tgcatctgag atcagagcac ggagctcagc agcaccaggc tgaattcccc      480

atgagtcctg tgacctcagt gcacgggggg acctacaggt gcttcagctc acacggcttc      540

tcccactacc tgctgtcaca ccccagtgac cccctggagc tcatagtctc aggatccttg      600

gagggtccca ggccctcacc cacaaggtcc gtctcaacag ctgcaggccc tgaggaccag      660

cccctcatgc ctacagggtc agtcccccac agtggtctga gaaggcactg ggag            714


<210>  3919
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  3919
ggcaccctcc ccaaacccac cctctgggct gagccagcct ctgtgatagc tcgggggaag       60

cccgtgaccc tctggtgtca ggggcccctg gagactgagg agtaccgtct ggataaggag      120

ggactcccat gggcccggaa gagacagaac ccactggagc ctggagccaa ggccaagttc      180

cacattccat ccacggtgta tgacagtgca gggcgatacc gctgctacta tgagacccct      240

gcaggctggt cagagcccag tgaccccctg gagctggtgg cgacaggatt ctatgcagaa      300

cccactcttt tagccctgcc gagtcctgtg gtggcctcag gaggaaatgt gaccctccag      360

tgtgatacac tggacggact tctcacgttt gttcttgttg aggaagaaca gaagctcccc      420

aggaccctgt actcacagaa gctccccaaa gggccatccc aggccctgtt ccctgtgggt      480

cccgtgaccc ccagctgcag gtggaggttc agatgctatt actattacag gaaaaaccct      540

caggtgtggt cgaaccccag tgacctcctg gagattctgg tcccaggcgt gtctaggaag      600

ccctccctcc tgatcccgca gggctctgtc gtggcccgcg gaggcagcct gaccctgcag      660

tgtcgctctg atgtcggcta tgacatattc gttctgtaca aggaggggga acatgacctc      720

gtccagggct ctggccagca gccccaggct gggctctccc aggccaactt caccctgggc      780

cctgtgagcc gctcccacgg gggccagtac agatgctacg gtgcacacaa cctctcccct      840

aggtggtcgg cccccagcga ccccctggac atcctgatcg caggactgat ccctgacata      900

cccgccctct cggtgcagcc gggccccaag gtggcctcag gagagaacgt gaccctgctg      960

tgtcagtcat ggcatcagat agacactttc tttttgacca aggagggggc agcccatccc     1020

ccgctgtgtc taaagtcaaa gtaccagtct tatagacacc aggctgaatt ctccatgagt     1080

cctgtgacct cagcccaggg tggaacctac cgatgctaca gcgcaatcag gtcctacccc     1140

tacctgctgt ccagccctag ttacccccag gagctcgtgg tctcaggacc ctctggggat     1200

cccagcctct cacctacagg ctccaccccc acacctggcc ctgaggacca gcccctcacc     1260

cccacggggt tggatcccca gagtggtctg ggaaggcacc tgggg                     1305


<210>  3920
<211>  1272
<212>  DNA
<213>  Homo Sapiens

<400>  3920
gggcccttcc ccaaacccac cctctgggct gagccaggct ctgtgatcag ctgggggagc       60

cccgtgacca tctggtgtca ggggagcctg gaggcccagg agtaccaact ggataaagag      120

ggaagcccag agcccttgga cagaaataac ccactggaac ccaagaacaa ggccagattc      180

tccatcccat ccatgacaca gcaccatgca gggagatacc gctgccacta ttacagctct      240

gcaggctggt cagagcccag cgaccccctg gagctggtga tgacaggatt ctacaacaaa      300

cccaccctct cagccctgcc cagccctgtg gtggcctcag gggggaatat gaccctccga      360

tgtggctcac agaagggata tcaccatttt gttctgatga aggaaggaga acaccagctc      420

ccccggaccc tggactcaca gcagctccac agtggggggt tccaggccct gttccctgtg      480

ggccccgtga cccccagcca caggtggagg ttcacatgct attactatta tacaaacacc      540

ccccgggtgt ggtcccaccc cagtgacccc ctggagattc tgccctcagg cgtgtctagg      600

aagccctccc tcctgaccct gcagggccct gtcctggccc ctgggcagag cctgaccctc      660

cagtgtggct ctgatgtcgg ctacgacaga tttgttctgt ataaggaggg ggaacgtgac      720

ttcctccagc gccctggcca gcagccccag gctgggctct cccaggccaa cttcaccctg      780

ggccctgtga gcccctccca cgggggccag tacaggtgct atggtgcaca caacctctcc      840

tccgagtggt cggcccccag cgaccccctg aacatcctga tggcaggaca gatctatgac      900

accgtctccc tgtcagcaca gccgggcccc acagtggcct caggagagaa cgtgaccctg      960

ctgtgtcagt cacggggtta ttttgacact ttccttctga ccaaagaagg ggcagcccat     1020

cccccactgc gtctgagatc aatgtacgga gctcataagt accaggctga attccccatg     1080

agtcctgtga cctcagccca cgcggggacc tacaggtgct acggctcata cagctccaac     1140

ccccacctgc tgtctttccc cagtgagccc ctggaactca tggtctcagg acactctgga     1200

ggctccagcc tcccacccac agggccgccc tccacacctg cctcacacgc caaggattac     1260

acagtggaga at                                                         1272


<210>  3921
<211>  1560
<212>  DNA
<213>  Homo Sapiens

<400>  3921
tgcccgcccc gctgcgagtg ctccgcccag gaccgcgctg tgctgtgcca ccgcaagcgc       60

tttgtggcag tccccgaggg catccccacc gagacgcgcc tgctggacct aggcaagaac      120

cgcatcaaaa cgctcaacca ggacgagttc gccagcttcc cgcacctgga ggagctggag      180

ctcaacgaga acatcgtgag cgccgtggag cccggcgcct tcaacaacct cttcaacctc      240

cggacgctgg gtctccgcag caaccgcctg aagctcatcc cgctaggcgt cttcactggc      300

ctcagcaacc tgaccaagct ggacatcagc gagaacaaga tcgttatcct actggactac      360

atgtttcagg acctgtacaa cctcaagtca ctggaggttg gcgacaatga cctcgtctac      420

atctctcacc gcgccttcag cggcctcaac agcctggagc agctgacgct ggagaaatgc      480

aacctgacct ccatccccac cgaggcgctg tcccacctgc acggcctcat cgtcctgagg      540

ctccggcacc tcaacatcaa tgccatccgg gactactcct tcaagaggct gtaccgactc      600

aaggtcttgg agatctccca ctggccctac ttggacacca tgacacccaa ctgcctctac      660

ggcctcaacc tgacgtccct gtccatcaca cactgcaatc tgaccgctgt gccctacctg      720

gccgtccgcc acctagtcta tctccgcttc ctcaacctct cctacaaccc catcagcacc      780

attgagggct ccatgttgca tgagctgctc cggctgcagg agatccagct ggtgggcggg      840

cagctggccg tggtggagcc ctatgccttc cgcggcctca actacctgcg cgtgctcaat      900

gtctctggca accagctgac cacactggag gaatcagtct tccactcggt gggcaacctg      960

gagacactca tcctggactc caacccgctg gcctgcgact gtcggctcct gtgggtgttc     1020

cggcgccgct ggcggctcaa cttcaaccgg cagcagccca cgtgcgccac gcccgagttt     1080

gtccagggca aggagttcaa ggacttccct gatgtgctac tgcccaacta cttcacctgc     1140

cgccgcgccc gcatccggga ccgcaaggcc cagcaggtgt ttgtggacga gggccacacg     1200

gtgcagtttg tgtgccgggc cgatggcgac ccgccgcccg ccatcctctg gctctcaccc     1260

cgaaagcacc tggtctcagc caagagcaat gggcggctca cagtcttccc tgatggcacg     1320

ctggaggtgc gctacgccca ggtacaggac aacggcacgt acctgtgcat cgcggccaac     1380

gcgggcggca acgactccat gcccgcccac ctgcatgtgc gcagctactc gcccgactgg     1440

ccccatcagc ccaacaagac cttcgctttc atctccaacc agccgggcga gggagaggcc     1500

aacagcaccc gcgccactgt gcctttcccc ttcgacatca agaccctcat catcgccacc     1560


<210>  3922
<211>  1554
<212>  DNA
<213>  Homo Sapiens

<400>  3922
tgccccgctc gctgtgagtg ctctgcccag aacaaatctg ttagctgtca cagaaggcga       60

ttgatcgcca tcccagaggg cattcccatc gaaaccaaaa tcttggacct cagtaaaaac      120

aggctaaaaa gcgtcaaccc tgaagaattc atatcatatc ctctgctgga agagatagac      180

ttgagtgaca acatcattgc caatgtggaa ccaggagcat tcaacaatct gtttaacctg      240

cgttccctcc gcctaaaagg caatcgtcta aagctggtcc ctttgggagt attcacgggg      300

ctgtccaatc tcactaagct tgacattagt gagaataaga ttgtcatttt actagactac      360

atgttccaag atctacataa cctgaagtct ctagaagtgg gggacaatga tttggtttat      420

atatcacaca gggcattcag tgggcttctt agcttggagc agctcaccct ggagaaatgc      480

aacttaacag cagtaccaac agaagccctc tcccacctcc gcagcctcat cagcctgcat      540

ctgaagcatc tcaatatcaa caatatgcct gtgtatgcct ttaaaagatt gttccacctg      600

aaacacctag agattgacta ttggccttta ctggatatga tgcctgccaa tagcctctac      660

ggtctcaacc tcacatccct ttcagtcacc aacaccaatc tgtctactgt acccttcctt      720

gcctttaaac acctggtata cctgactcac cttaacctct cctacaatcc catcagcact      780

attgaagcag gcatgttctc tgacctgatc cgccttcagg agcttcatat agtgggggcc      840

cagcttcgca ccattgagcc tcactccttc caagggctcc gcttcctacg cgtgctcaat      900

gtgtctcaga acctgctgga aactttggaa gagaatgtct tctcctcccc tagggctctg      960

gaggtcttga gcattaacaa caaccctctg gcctgtgact gccgccttct ctggatcttg     1020

cagcgacagc ccaccctgca gtttggtggc cagcaaccta tgtgtgctgg cccagacacc     1080

atccgtgaga ggtctttcaa ggatttccat agcactgccc tttcttttta ctttacctgc     1140

aaaaaaccca aaatccgtga aaagaagttg cagcatctgc tagtagatga agggcagaca     1200

gtccagctag aatgcagtgc agatggagac ccgcagcctg tgatttcctg ggtgacaccc     1260

cgaaggcgtt tcatcaccac caagtccaat ggaagagcca ccgtgttggg tgatggcacc     1320

ttggaaatcc gctttgccca ggatcaagac agcgggatgt atgtttgcat cgctagcaat     1380

gctgctggga atgatacctt cacagcctcc ttaactgtga aaggattcgc ttcagatcgt     1440

tttctttatg cgaacaggac ccctatgtac atgaccgact ccaatgacac catttccaat     1500

ggcaccaatg ccaatacttt ttccctggac cttaaaacaa tactggtgtc taca           1554


<210>  3923
<211>  1521
<212>  DNA
<213>  Homo Sapiens

<400>  3923
tgcccagctc gttgcgagtg cactgtgcaa actagggccg tcgcttgcac gagacgtaga       60

ttgacggcag taccagacgg aataccagcc gagacacgtc tgctggaact tagtcgtaac      120

agaattcgtt gtcttaaccc cggggatctg gccgcgcttc cggccctgga ggagctagac      180

ttgagcgaaa atgcaatcgc acacgtagag cctggtgcat ttgctaactt accaagattg      240

agagtattga ggttgcgtgg caaccaactg aagttgattc cacccggtgt tttcacgcgt      300

ctagataatc ttaccctact agacctgagt gagaacaaat tagtcatact gcttgattac      360

acttttcaag acttgcatag tttaaggcgt cttgaggtcg gtgacaatga tttagtgttc      420

gtttctagac gtgcatttgc cgggcttttg gctctagagg agcttactct ggagcgttgt      480

aacttgactg cgctgagcgg tgaaagttta ggtcatctga ggagtctggg agcattacgt      540

ctacgtcacc tagccattgc ttcactagag gatcagaact tccgtagatt gcctgggtta      600

ttgcatttgg aaatcgacaa ctggcctctg cttgaggaag tggcggcggg atccttgagg      660

gggctgaact tgacttccct gtcagtcacc cacactaaca tcacggctgt gccagccgcg      720

gccctgcgtc accaggccca tcttacctgt cttaacttgt cacacaatcc catctccaca      780

gtgcctcgtg ggtctttcag agacttggta cgtttacgtg aattgcacct ggctggtgca      840

ttattggccg ttgtggaacc gcaagcattc ctagggctta ggcaaattag attgctaaat      900

cttagtaaca acttattaag tacgttagag gaatcaacct ttcacagcgt gaacacgttg      960

gagacgttaa gggttgatgg caacccactg gcctgcgact gccgtcttct atggatcgta     1020

caaagaagaa agaccttgaa tttcgatggt agacttccag catgcgcgac accggccgaa     1080

gtaagagggg atgctttaag gaacctacca gattcagtac tattcgagta cttcgtttgt     1140

cgtaaaccaa aaatcagaga gaggaggctt caaagggtga ccgcgacagc tggggaagat     1200

gtaaggtttt tatgcagagc tgagggggag ccagccccga ccgtcgcctg ggtaacccca     1260

caacataggc ccgtaaccgc aacgtccgca ggacgtgctc gtgtactacc gggcggtacc     1320

ctggaaatcc aagacgcgcg tcctcaagat tcaggcactt atacgtgtgt tgcaagtaat     1380

gccggtggta atgacactta ttttgcgacg ctgacagtac gtccagaacc tgctgctaac     1440

agaactcccg gagaggcgca caacgagact ctagcagcgt tgcgtgcgcc attagactta     1500

acaaccattc tagtttctac g                                               1521


<210>  3924
<211>  1515
<212>  DNA
<213>  Homo Sapiens

<400>  3924
ggcagctgcc ctgctgtgtg tgactgcacc tcccagcccc aggctgtgct ctgtggccac       60

aggcaactgg aggctgtacc tggaggactc ccactggaca ctgagctcct ggacctgagt      120

gggaaccgcc tgtgggggct ccagcaggga atgctctccc gcctgagcct gctccaggaa      180

ttggacctca gctacaacca gctctcaacc cttgagcctg gggccttcca tggcctacaa      240

agcctactca ccctgaggct gcagggcaat cggctcagaa tcatggggcc tggggtcttc      300

tcaggcctct ctgctctgac cctgctggac ctccgcctca accagattgt tctcttccta      360

gatggagctt ttggggagct aggcagcctc cagaagctgg aggttgggga caaccacctg      420

gtatttgtgg ctccgggggc ctttgcaggg ctagccaagt tgagcaccct caccctggag      480

cgctgcaacc tcagcacagt gcctggccta gcccttgccc gtctcccggc actagtggcc      540

ctaaggctta gagaactgga tattgggagg ctgccagctg gggccctgcg ggggctgggg      600

cagctcaagg agctggagat ccacctctgg ccatctctgg aggctctgga ccctgggagc      660

ctggttgggc tcaatctcag cagcctggcc atcactcgct gcaatctgag ctcggtgccc      720

ttccaagcac tgtaccacct cagcttcctc agggtcctgg atctgtccca gaatcccatc      780

tcagccatcc cagcccgaag gctcagcccc ctggtgcggc tccaggagct acgcctgtca      840

ggggcatgcc tcacctccat tgctgcccat gccttccatg gcttgactgc cttccacctc      900

ctggatgtgg cagataacgc ccttcagaca ctagaggaaa cagctttccc ttctccagac      960

aaactggtca ccttgaggct gtctggcaac cccctaacct gtgactgccg cctcctctgg     1020

ctgctccggc tccgccgcca cctggacttt ggcatgtccc cccctgcctg tgctggcccc     1080

catcatgtcc aggggaagag cctgaaggag ttttcagaca tcctgcctcc agggcacttc     1140

acctgcaaac cagccctgat ccgaaagtcg gggcctcgat gggtcattgc agaggagggc     1200

gggcatgcgg ttttctcctg ctctggagat ggagacccag cccccactgt ctcctggatg     1260

aggcctcatg gggcttggct gggcagggct gggagagtaa gggtcctaga ggatgggaca     1320

ctggagatcc gctcagtgca gctacgggac agaggggcct atgtctgtgt ggttagcaat     1380

gtcgctggga atgactccct gaggacctgg ctggaagtca tccaggtgga accaccaaac     1440

ggcacacttt ctgaccccaa catcaccgtg ccagggatcc cagggccttt ttttctggat     1500

agcagaggtg tggcc                                                      1515


<210>  3925
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  3925
gaggtgtggc caccccagct gcaggagcag gctccgatgg ccggagccct gaacaggaag       60

gagagtttct tgctcctctc cctgcacaac cgcctgcgca gctgggtcca gccccctgcg      120

gctgacatgc ggaggctgga ctggagtgac agcctggccc agctggctca agccagggca      180

gccctctgtg gaaccccaac cccgagcctg gcgtccggcc tgtggcgcac cctgcaagtg      240

ggctggaaca tgcagctgct acccgcgggc ttggtgtcct ttgtcgaagt ggtcagccta      300

tggtttgcag aggggcagcg gtacagccac gcggcaggag agtgtgctcg caacgccacc      360

tgcacccact acacgcagct cgtgtgggcc acctcaagcc agctgggctg tgggcggcac      420

ctgtgctctg caggccaggc agcgatagaa gcctttgtct gtgcctactc ccccagaggc      480

aactgggagg tcaacgggaa gacaatcgtc ccctataaga agggtgcctg gtgttcgctc      540

tgcacagcca gtgtctcagg ctgcttcaaa gcctgggacc atgcaggggg gctctgtgag      600

gtccccagga atccttgtcg catgagctgc cagaaccatg gacgtctcaa catcagcacc      660

tgccactgcc actgtccccc tggctacacg ggcagatact gccaagtgag gtgcagcctg      720

cagtgtgtgc acggccggct ccgggaggag gagtgctcgt gcgtctgtga catcggctac      780

gggggagccc agtgtgccac caaggtgcat tttcccttcc acacctgtga cctgaggatc      840

gacggagact gcttcatggt gtcttcagag gcagacacct attacagagc caggatgaaa      900

tgtcagagga aaggcggggt gctggcccag atcaagagcc agaaagtgca ggacatcctc      960

gccttctatc tgggccgcct ggagaccacc aacgaggtga ttgacagtga cttcgagacc     1020

aggaacttct ggatcgggct cacctacaag accgccaagg actccttccg ctgggccaca     1080

ggggagcacc aggccttcac cagttttgcc tttgggcagc ctgacaacca cgggtttggc     1140

aactgcgtgg agctgcaggc ttcagctgcc ttcaactgga acaaccagcg ctgcaaaacc     1200

cgaaaccgtt acatctgcca gtttgcccag gagcacatct cccggtgggg cccagggtcc     1260


<210>  3926
<211>  747
<212>  DNA
<213>  Homo Sapiens

<400>  3926
gacgaccctt acaaccccta caagtactct gacgacaacc cttattacaa ctactacgat       60

acttatgaaa ggcccagacc tgggggcagg taccggcccg gatacggcac tggctacttc      120

cagtacggtc tcccagacct ggtggccgac ccctactaca tccaggcgtc cacgtacgtg      180

cagaagatgt ccatgtacaa cctgagatgc gcggcggagg aaaactgtct ggccagtaca      240

gcatacaggg cagatgtcag agattatgat cacagggtgc tgctcagatt tccccaaaga      300

gtgaaaaacc aagggacatc agatttctta cccagccgac caagatattc ctgggaatgg      360

cacagttgtc atcaacatta ccacagtatg gatgagttta gccactatga cctgcttgat      420

gccaacaccc agaggagagt ggctgaaggc cacaaagcaa gtttctgtct tgaagacaca      480

tcctgtgact atggctacca caggcgattt gcatgtactg cacacacaca gggattgagt      540

cctggctgtt atgataccta tggtgcagac atagactgcc agtggattga tattacagat      600

gtaaaacctg gaaactatat cctaaaggtc agtgtaaacc ccagctacct ggttcctgaa      660

tctgactata ccaacaatgt tgtgcgctgt gacattcgct acacaggaca tcatgcgtat      720

gcctcaggct gcacaatttc accgtat                                          747


<210>  3927
<211>  1440
<212>  DNA
<213>  Homo Sapiens

<400>  3927
cggcaggcgc cgtccctgcc cctgccgggg cgcgtgggct cggacaccgt gcgcggccag       60

gcgcggcacc cattcggctt tggccaggtg cccgacaact ggcgcgaggt ggccgtcggg      120

gacagcacgg gcatggcccg ggcccgcacc tccgtctccc agcaacggca cggggactcc      180

gcctcctcgg tctcggcttc ggccttcgcc agcacctacc gccagcagcc ctcctacccg      240

cagcagttcc cctacccgca ggcgcccttc gtcagccagt acgagaacta cgaccccgcg      300

tcgcggacct acgaccaggg tttcgtgtac taccggcccg cgggcggcgg cgtgggcgcg      360

ggggcggcgg ccgtggcctc ggcgggggtc atctacccct accagccccg ggcgcgctac      420

gaggagtacg gcggcggcga agagctgccc gagtacccgc ctcagggctt ctacccggcc      480

cccgagaggc cctacgtgcc gccgccgccg ccgccccccg acggcctgga ccgccgctac      540

tcgcacagtc tgtacagcga gggcaccccc ggcttcgagc aggcctaccc tgaccccggt      600

cccgaggcgg cgcaggccca tggcggagac ccacgcctgg gctggtaccc gccctacgcc      660

aacccgccgc ccgaggcgta cgggccgccg cgcgcgctgg agccgcccta cctgccggtg      720

cgcagctccg acacgccccc gccgggtggg gagcggaacg gcgcgcagca gggccgcctc      780

agcgtgggca gcgtgtaccg gcccaaccag aacggccgcg gtctccctga cttggtccca      840

gaccccaact atgtgcaagc atccacttat gtgcagagag cccacctgta ctccctgcgc      900

tgtgctgcgg aggagaagtg tctggccagc acagcctatg cccctgaggc caccgactac      960

gatgtgcggg tgctactgcg cttcccccag cgcgtgaaga accagggcac agcagacttc     1020

ctccccaacc ggccacggca cacctgggag tggcacagct gccaccagca ttaccacagc     1080

atggacgagt tcagccacta cgacctactg gatgcagcca caggcaagaa ggtggccgag     1140

ggccacaagg ccagtttctg cctggaggac agcacctgtg acttcggcaa cctcaagcgc     1200

tatgcatgca cctctcatac ccagggcctg agcccaggct gctatgacac ctacaatgcg     1260

gacatcgact gccagtggat cgacataacc gacgtgcagc ctgggaacta catcctcaag     1320

gtgcacgtga acccaaagta tattgttttg gagtctgact tcaccaacaa cgtggtgaga     1380

tgcaacattc actacacagg tcgctacgtt tctgcaacaa actgcaaaat tgtccaatcc     1440


<210>  3928
<211>  1887
<212>  DNA
<213>  Homo Sapiens

<400>  3928
ggtaacctcc ctggtgttca ctgcggccca agctccgggg caggccctgg ttttggcccg       60

ggctcgtgga gccgctctct cgatcgagcc ctggaggagg cggcggtcac tggggtgctg      120

agcctgagcg gccggaaact gagggagttt ccccggggag cggccaacca cgacctgacg      180

gacaccaccc gggcggacct gtcgcgaaat cgcctttcag aaattcctat agaagcatgt      240

cactttgttt ctctggaaaa tctcaacttg taccaaaatt gtattcgtta tattccagag      300

gcaattttaa acctacaagc tctaacattc ttaaatatta gtcggaacca actgtcaaca      360

ttgccggtac acttgtgtaa tttgccattg aaagtcttaa ttgctagtaa taacaaattg      420

gtgtcacttc cagaagaaat tggacacctt agacatttga tggaacttga tgtgagctgc      480

aatgaaattc aaactatacc ttcccaaatt ggtaacctgg aggccttgag agaccttaat      540

gtaagaagaa atcacctagt acatttgcct gaagagctgg cggagttgcc tttgatacgg      600

ttagacttct catgcaataa aattaccaca atccctgttt gttatcggaa cctcaggcac      660

ctacagacga tcaccctaga taacaatcca ctacaatcac ctcctgcaca gatatgtata      720

aaaggcaaag tccacatatt taaatacctg aacatacaag cttgtaagat tgctccagat      780

ctgccggatt atgataggag accgttgggt tttggctcct gccatgaaga actgtactca      840

agtcgccctt atggagccct tgattcaggc ttcaatagtg tggacagtgg tgataagaga      900

tggtcaggga atgaacctac agatgaattt tcagatctgc ctcttcgagt agcagagatt      960

actaaagaac aaagactacg aagagaaagc cagtaccaag agaaccgcgg cagtttggta     1020

gtaacaaacg gcggagtgga acatgatctg gatcagattg actacataga cagctgcacc     1080

gcagaggaag aggaggccga ggtgagacag cccaagggac cagacccaga cagccttagt     1140

tcacagttta tggcgtatat tgaacagcgg cgaatctctc atgagggttc accagtaaag     1200

ccagtagcca ttagggagtt tcaaaaaaca gaagatatga gaagatactt acatcaaaac     1260

agggttccag ctgagccatc ttccctcctg tcactatcag caagtcacaa tcagctgtca     1320

cacacagacc tggaacttca tcagagaagg gagcagttag tagagcgcac tcggagagag     1380

gctcagcttg ctgccctgca gtatgaggag gagaaaataa ggaccaagca gatccagaga     1440

gatgctgtcc tggactttgt caaacaaaaa gcatcacaaa gtccacaaaa acagcacccg     1500

ctcctagatg gcgtagatgg tgagtgcccc ttcccatcca gaaggtctca gcacactgat     1560

gatagtgcct tgtgcatgtc gctgtcaggg ttgaatcaag tgggctgtgc tgctaccctg     1620

cctcattctt ctgccttcac gcctcttaag agtgatgaca gacctaatgc tctattaagt     1680

tcacctgcaa cagaaacagt tcatcattcc cctgcatatt cttttcctgc tgctatccag     1740

agaaatcagc ctcagcgccc tgaaagcttc cttttccgag caggtgtcag ggcagaaacc     1800

aacaaaggtc atgcttcacc ccttcctcca tctgctgcac ctaccactga ttctacagat     1860

tccataacag gacagaattc aagacag                                         1887


<210>  3929
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  3929
ccattgatca cacggcaggc ggggggccgg gccctggtgg tggaaggcca ggcggtgagc       60

ctgcgctgcc gagcggtggg tgaccccgag ccggtggtgc actgggtggc acctgatggg      120

cggctgctgg ggaactccag ccggacccgg gtccgggggg acgggacgct ggatgtgacc      180

atcaccacct tgagggacag tggcaccttc acttgtatcg cctccaatgc tgctggggaa      240

gcgacggcgc ccgtggaggt gtgcgtggta cctctgcctc tgatggcacc cccgccggct      300

gccccgccgc ctctcaccga gcccggctcc tctgacatcg ccacgccggg cagaccaggt      360

gccaacgatt ctgcggctga gcgtcggctc gtggcagccg agctcacctc gaactccgtg      420

ctcatccgct ggccagccca gaggcctgtg cccggaatac gcatgtacca ggttcagtac      480

aacagttccg ttgatgactc cctcgtctac aggatgatcc cgtccaccag tcagaccttc      540

ctggtgaatg acctggcggc gggccgtgcc tacgacttgt gcgtgctggc ggtctacgac      600

gacggggcca cagcgctgcc ggcaacgcga gtggtgggct gtgtacagtt caccaccgct      660

ggggatccgg cgccctgccg cccgctgagg gcccatttct tgggcggcac catg            714


<210>  3930
<211>  1542
<212>  DNA
<213>  Homo Sapiens

<400>  3930
tgccccaagt actgtgtctg ccagaatctg tctgagtcac tggggaccct gtgcccctcc       60

aaggggctgc tctttgtacc ccctgatatt gaccggcgga cagtggagct gcgcctgggc      120

ggcaacttca tcatccacat cagccgccag gactttgcca acatgacggg gctggtggac      180

ctgaccctgt ccaggaacac catcagccac atccagccct tttcctttct ggacctcgag      240

agcctccgct ccctgcatct tgacagcaat cggctgccaa gccttgggga ggacaccctc      300

cggggcctgg tcaacctgca gcaccttatc gtgaacaaca accagctggg cggcatcgca      360

gatgaggctt ttgaggactt cctgctgaca ttggaggatc tggacctctc ctacaacaac      420

ctccatggcc tgccgtggga ctccgtgcga cgcatggtca acctccacca gctgagcctg      480

gaccacaacc tgctggatca catcgccgag ggcacctttg cagacctgca gaaactggcc      540

cgcctggatc tcacctccaa tcggctgcag aagctgcccc ctgatcccat ctttgcccgc      600

tcccaggctt cggctttgac agccacaccc tttgccccac ccttgtcctt tagttttggg      660

ggtaacccac ttcactgcaa ttgtgagctt ctctggctgc ggaggctcga gcgggacgat      720

gacctggaaa cctgtggctc cccagggggc ctcaagggtc gctacttctg gcatgtgcgt      780

gaggaggagt ttgtgtgcga gccgcctctc atcacccagc acacacacaa gttgctggtt      840

ctggagggcc aggcggccac actcaagtgc aaagccattg gggaccccag cccccttatc      900

cactgggtag cccccgatga ccgcctggta gggaactcct caaggaccgc tgtctatgac      960

aatggcaccc tggacatctt catcaccaca tctcaggaca gtggtgcctt cacctgcatt     1020

gctgccaatg ctgccggaga ggccacggcc atggtggagg tctccatcgt ccagctgcca     1080

cacctcagca acagcaccag ccgcactgca ccccccaagt cccgcctctc agacatcact     1140

ggctccagca agaccagccg gggaggtgga ggcagtgggg gcggagagcc tcccaaaagc     1200

cccccggaac gggctgtgct tgtgtctgaa gtgaccacca cctcggccct ggtcaagtgg     1260

tctgtcagca agtcagcacc ccgggtgaag atgtaccagc tgcagtacaa ctgctctgac     1320

gatgaggtac tgatttacag gatgatccca gcctccaaca aggccttcgt ggtcaacaac     1380

ctggtgtcag ggactggcta cgacttgtgt gtgctggcca tgtgggatga cacagccacg     1440

acactcacgg ccaccaacat cgtgggctgc gcccagttct tcaccaaggc tgactacccg     1500

cagtgccagt ccatgcacag ccagattctg ggcggcacca tg                        1542


<210>  3931
<211>  1569
<212>  DNA
<213>  Homo Sapiens

<400>  3931
tcatccccac cccagtcagc cacacccagc ccatgtcccc gccgctgccg ctgccagaca       60

cagtcgctgc ccctaagcgt gctgtgccca ggggcaggcc tcctgttcgt gccaccctcg      120

ctggaccgcc gggcagccga gctgcggctg gcagacaact tcatcgcctc cgtgcgccgc      180

cgcgacctgg ccaacatgac aggcctgctg catctgagcc tgtcgcggaa caccatccgc      240

cacgtggctg ccggcgcctt cgccgacctg cgggccctgc gtgccctgca cctggatggc      300

aaccggctga cctcactggg cgagggccag ctgcgcggcc tggtcaactt gcgccacctc      360

atcctcagca acaaccagct ggcagcgctg gcggccggcg ccctggatga ttgtgccgag      420

acactggagg acctcgacct ctcctacaac aacctcgagc agctgccctg ggaggccctg      480

ggccgcctgg gcaacgtcaa cacgttgggc ctcgaccaca acctgctggc ttctgtgccc      540

gccggcgctt tttcccgcct gcacaagctg gcccggctgg acatgacctc caaccgcctg      600

accacaatcc cacccgaccc actcttctcc cgcctgcccc tgctcgccag gccccggggc      660

tcgcccgcct ctgccctggt gctggccttt ggcgggaacc ccctgcactg caactgcgag      720

ctggtgtggc tgcgtcgcct ggcgcgggag gacgacctcg aggcctgcgc gtccccacct      780

gctctgggcg gccgctactt ctgggcggtg ggcgaggagg agtttgtctg cgagccgccc      840

gtggtgactc accgctcacc acctctggct gtgcccgcag gtcggccggc tgccctgcgc      900

tgccgggcag tgggggaccc agagccccgt gtgcgttggg tgtcacccca gggccggctg      960

ctaggcaact caagccgtgc ccgcgccttc cccaatggga cgctggagct gctggtcacc     1020

gagccgggtg atggtggcat cttcacctgc attgcggcca atgcagctgg cgaggccaca     1080

gctgctgtgg agctgactgt gggtccccca ccacctcctc agctagccaa cagcaccagc     1140

tgtgaccccc cgcgggacgg ggatcctgat gctctcaccc caccctccgc tgcctctgct     1200

tctgccaagg tggccgacac tgggccccct accgaccgtg gcgtccaggt gactgagcac     1260

ggggccacag ctgctcttgt ccagtggccg gatcagcggc ctatcccggg catccgcatg     1320

taccagatcc agtacaacag ctcggctgat gacatcctcg tctacaggat gatcccggcg     1380

gagagccgct cgttcctgct gacggacctg gcgtcaggcc ggacctacga tctgtgcgtg     1440

ctcgccgtgt atgaggacag cgccacgggg ctcacggcca cgcggcctgt gggctgcgcc     1500

cgcttctcca ccgaacctgc gctgcggcca tgcggggcgc cgcacgctcc cttcctgggc     1560

ggcacgatg                                                             1569


<210>  3932
<211>  1506
<212>  DNA
<213>  Homo Sapiens

<400>  3932
tgcccgctgc cctgcgtctg ccagaacctg tccgagtcgc tcagcaccct ctgtgcccac       60

cgaggcctgc tgtttgtgcc gcccaacgtg gaccggcgca cagtggagct gcggctggct      120

gacaacttca tccaggccct ggggccccct gacttccgca acatgacggg actggtggac      180

ctgacactgt ctcgcaatgc catcacccgc attggggccc gcgcctttgg ggacctcgag      240

agcctgcgtt ccctccacct tgacggcaac aggctggtgg agctgggcac cgggagcctc      300

cggggccccg tcaatctgca gcacctcatc ctcagcggca accagctggg ccgcatcgcg      360

ccgggagcct tcgacgactt cctagagagc ctggaggacc tggacctgtc ctacaacaac      420

ctccggcagg tgccctgggc cggcatcggc gccatgcctg ccctgcacac cctcaacctg      480

gaccataacc ttattgacgc actgccccca ggcgccttcg cccagctcgg tcagctctcc      540

cgcctggacc tcacctccaa ccgcctggcc acgctggctc cggacccgct tttctctcgt      600

gggcgtgatg cagaggcctc tcccgccccc ctggtgctga gctttagcgg gaaccccctg      660

cactgcaact gtgagctgct gtggctgcgg cggctggcgc ggccggacga cctggaaacg      720

tgcgcctccc cgcccggcct ggccggccgc tacttctggg cagtgcccga gggcgagttc      780

tcctgtgagc cgcccctcat tgcccgccac acgcagcgcc tctgggtgct ggaaggccag      840

cgggccacgc tgcggtgccg ggccctgggt gaccccgcgc ctaccatgca ctgggtcggt      900

cctgacgacc ggttggttgg caactcctcc cgagcccggg ctttccccaa cgggacctta      960

gagattgggg tgaccggcgc tggggacgct gggggctaca cctgcatcgc caccaaccct     1020

gctggtgagg ccacagcccg agtagaactg cgggtgctgg ccttgcccca tggtgggaac     1080

agcagtgccg aggggggccg ccccgggccc tcggacatcg ccgcctccgc tcgcactgct     1140

gccgagggtg aggggacgct ggagtctgag ccagccgtgc aggtgacgga ggtgaccgcc     1200

acctcagggc tggtgagctg gggtcccggg cggccagccg acccagtgtg gatgttccaa     1260

atccagtaca acagcagcga agatgagacc ctcatctacc ggattgtccc agcctccagc     1320

caccacttcc tgctgaagca cctcgtcccc ggcgctgact atgacctctg cctgctggcc     1380

ttgtcaccgg ccgctgggcc ctctgacctc acggccacca ggctgctggg ctgtgcccat     1440

ttctccacgc tgccggcctc gcccctgtgc cacgccctgc aggcccacgt gctgggcggg     1500

accctg                                                                1506


<210>  3933
<211>  1536
<212>  DNA
<213>  Homo Sapiens

<400>  3933
cagatctgtc caaagcgttg tgtctgtcag attttgtctc ctaatcttgc aaccctttgt       60

gccaagaaag ggcttttatt tgttccacca aacattgaca gaagaactgt ggaactgcgg      120

ttggcagaca attttgttac aaatattaaa aggaaagatt ttgccaatat gaccagcttg      180

gtggacctga ctctatccag gaatacaata agttttatta cacctcatgc tttcgctgac      240

ctacgaaatt tgagggcttt gcatttgaat agcaacagat tgactaaaat tacaaatgat      300

atgttcagtg gtctttccaa tcttcatcat ttgatactga acaacaatca gctgacttta      360

atttcctcta cagcgtttga tgatgtcttc gcccttgagg agctggatct gtcctataat      420

aatctagaaa ccattccttg ggatgctgtt gagaagatgg ttagcttgca tacccttagt      480

ttggatcaca atatgattga taacattcct aaggggacct tctcccattt gcacaagatg      540

actcggttag atgtgacatc aaataaattg cagaagctac cacctgaccc tctctttcag      600

cgagctcagg tactagcaac ctcaggaatc ataagcccat ctacttttgc attaagtttt      660

ggtggaaacc cattgcattg caattgtgaa ttgttgtggt tgaggcgtct gtccagagaa      720

gatgacttag agacctgtgc ttctcctcca cttttaactg gccgctactt ttggtcaatt      780

cctgaagaag agtttttgtg tgagcctcct ctcattactc gtcatacaca tgagatgaga      840

gtcctggagg gacaaagggc aacactgagg tgcaaagcca ggggagaccc tgagcctgca      900

attcactgga tttctcctga agggaagctt atttcaaatg caacaagatc tctggtgtat      960

gataacggaa cacttgacat tcttatcaca actgtaaagg atacaggtgc ttttacctgc     1020

attgcttcca atcctgctgg ggaagcaaca caaatagtgg atcttcatat aattaagctc     1080

cctcacttac taaatagtac aaaccatatc catgagcctg atcctggttc ttcagatatc     1140

tcaacttcta ccaagtcagg ttctaataca agcagtagta atggtgatac taaattgagt     1200

caagataaaa ttgtggtggc agaagctaca tcatcaacgg cactacttaa atttaatttt     1260

caaagaaata tccctggaat acgtatgttt caaatccagt acaatggtac ttatgatgac     1320

acccttgttt acagaatgat acctcctacg agcaaaactt ttctggtcaa taatctggct     1380

gctggaacta tgtatgactt gtgtgtcttg gccatatatg atgatggcat cacttccctc     1440

actgccacaa gagtcgtggg ttgcatccag tttactacgg aacaggatta tgtgcgttgc     1500

catttcatgc agtcccagtt tttgggaggc accatg                               1536


<210>  3934
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  3934
gtcaccctga gccccaaaga ctgccaggtg ttccgctcag accatggcag ctccatctcc       60

tgtcaaccac ctgccgaaat ccccggctac ctgccagccg acaccgtgca cctggccgtg      120

gaattcttca acctgaccca cctgccagcc aacctcctcc agggcgcctc taagctccaa      180

gaattgcacc tctccagcaa tgggctggaa agcctctcgc ccgaattcct gcggccagtg      240

ccgcagctga gggtgctgga tctaacccga aacgccctga ccgggctgcc ctcgggcctc      300

ttccaggcct cagccaccct ggacaccctg gtattgaaag aaaaccagct ggaggtcctg      360

gaggtctcgt ggctacacgg cctgaaagct ctggggcatc tggacctgtc tgggaaccgc      420

ctccggaaac tgccccccgg gctgctggcc aacttcaccc tcctgcgcac ccttgacctt      480

ggggagaacc agttggagac cttgccacct gacctcctga ggggtccgct gcaattagaa      540

cggctacatc tagaaggcaa caaattgcaa gtactgggaa aagatctcct cttgccgcag      600

ccggacctgc gctacctctt cctgaacggc aacaagctgg ccagggtggc agccggtgcc      660

ttccagggcc tgcggcagct ggacatgctg gacctctcca ataactcact ggccagcgtg      720

cccgaggggc tctgggcatc cctagggcag ccaaactggg acatgcggga tggcttcgac      780

atctccggca acccctggat ctgtgaccag aacctgagcg acctctatcg ttggcttcag      840

gcccaaaaag acaagatgtt ttcccagaat gacacgcgct gtgctgggcc tgaagccgtg      900

aagggccaga cgctcctggc agtggccaag tcccag                                936


<210>  3935
<211>  2211
<212>  DNA
<213>  Homo Sapiens

<400>  3935
gccggcccgc gggcgccctg cgcggccgcc tgcacttgcg ctggggactc gctggactgc       60

ggtgggcgcg ggctggctgc gttgcccggg gacctgccct cctggacgcg gagcctaaac      120

ctgagttaca acaaattctc tgagattgac cctgctggtt ttgaggactt gccgaaccta      180

caggaagtgt acctcaataa taatgagttg acagcggtac catccctggg cgctgcttca      240

tcacatgtcg tctctctctt tctgcagcac aacaagattc gcagcgtgga ggggagccag      300

ctgaaggcct acctttcctt agaagtgtta gatctgagtt tgaacaacat cacggaagtg      360

cggaacacct gctttccaca cggaccgcct ataaaggagc tcaacctggc aggcaatcgg      420

attggcaccc tggagttggg agcatttgat ggtctgtcac ggtcgctgct aactcttcgc      480

ctgagcaaaa acaggatcac ccagcttcct gtaagagcat tcaagctacc caggctgaca      540

caactggacc tcaatcggaa caggattcgg ctgatagagg gcctcacctt ccaggggctc      600

aacagcttgg aggtgctgaa gcttcagcga aacaacatca gcaaactgac agatggggcc      660

ttctggggac tgtccaagat gcatgtgctg cacctggagt acaacagcct ggtagaagtg      720

aacagcggct cgctctacgg cctcacggcc ctgcatcagc tccacctcag caacaattcc      780

atcgctcgca ttcaccgcaa gggctggagc ttctgccaga agctgcatga gttggtcctg      840

tccttcaaca acctgacacg gctggacgag gagagcctgg ccgagctgag cagcctgagt      900

gtcctgcgtc tcagccacaa ttccatcagc cacattgcgg agggtgcctt caagggactc      960

aggagcctgc gagtcttgga tctggaccat aacgagattt cgggcacaat agaggacacg     1020

agcggcgcct tctcagggct cgacagcctc agcaagctcc ttttattaga gccatcccag     1080

tctgctggct gcagctcccc gtcccagccc catatgtctg ctgggggaag gactctgttt     1140

ggaaacaaga tcaagtctgt ggctaagaga gcattctcgg ggctggaagg cctggagcac     1200

ctgaaccttg gagggaatgc gatcagatct gtccagtttg atgcctttgt gaagatgaag     1260

aatcttaaag agctccatat cagcagcgac agcttcctgt gtgactgcca gctgaagtgg     1320

ctgcccccgt ggctaattgg caggatgctg caggcctttg tgacagccac ctgtgcccac     1380

ccagaatcac tgaagggtca gagcattttc tctgtgccac cagagagttt cgtgtgcgat     1440

gacttcctga agccacagat catcacccag ccagaaacca ccatggctat ggtgggcaag     1500

gacatccggt ttacatgctc agcagccagc agcagcagct cccccatgac ctttgcctgg     1560

aagaaagaca atgaagtcct gaccaatgca gacatggaga actttgtcca cgtccacgcg     1620

caggacgggg aagtgatgga gtacaccacc atcctgcacc tccgtcaggt cactttcggg     1680

cacgagggcc gctaccaatg tgtcatcacc aaccactttg gctccaccta ttcacataag     1740

gccaggctca ccgtgaatgt gttgccatca ttcaccaaaa cgccccacga cataaccatc     1800

cggaccacca ccatggcccg cctcgaatgt gctgccacag gtcacccaaa ccctcagatt     1860

gcctggcaga aggatggagg cacggatttc cccgctgccc agaccccatc cttggtggtc     1920

cccttggaag accgtgtggt atctgtggga gaaacagtgg ccctccaatg caaagccacg     1980

gggaaccctc cgccccgcat cacctggttc aagggggacc gcccgctgag cctcactgag     2040

cggcaccact tgacccctga caaccagctc ctggtggttc agaacgtggt ggcagaggat     2100

gcgggccgat atacctgtga gatgtccaac accctgggca cggagcgagc tcacagccag     2160

ctgagcgtcc tgcccgcagc aggctgcagg aaggatggga ccacggtagg c              2211


<210>  3936
<211>  2301
<212>  DNA
<213>  Homo Sapiens

<400>  3936
ggtctctgcc ccgcgccctg ctcctgccgc attcctctcc tggactgcag tcgcaggaaa       60

ttgcccgcac cgagctggag ggcgctgtcg ggcttgctgc cccccgacac cgctatcctg      120

gatttcagtc ataatcggtt gtctaactgg aacatcagct tggaatcaca aacattacag      180

gaagtgaaaa tgaattacaa tgaactaaca gaaatcccgt attttggaga acctacatct      240

aatattactc tactttcatt agtccataat ataatcccag aaataaatgc acaggcactc      300

cagttttacc ctgctctgga gagtttagac ctcagctcaa atataatatc agaaatcaag      360

acatcttcat ttcctcgcat gcagcttaaa tacctgaatt taagtaataa cagaataacc      420

accttggagg ctggttgctt cgataattta tcaagttcct tattagtggt aaagttaaac      480

cgtaaccgaa tgagcatgat tccacctaag atcttcaagc tgcctcacct ccaattcttg      540

gaacttaaaa gaaacagaat taaaattgtg gaaggtctta cattccaagg gcttgactcc      600

ttaagatctt tgaaaatgca gcggaatgga attagcaaac ttaaggatgg agcatttttt      660

ggcttgaata acatggaaga actagaactg gaacacaaca accttacacg agtaaacaag      720

gggtggttgt atggcttgcg aatgttacag cagctctatg tgagccagaa tgctattgaa      780

agaatcagcc ctgatgcatg ggagttctgc caaagactat ccgaacttga tttgtcctat      840

aaccagctga cccgcctgga tgaatctgcc tttgtgggtc tgagcttatt ggagagattg      900

aatttaggag acaacagagt cactcatatt gctgatggtg tatttagatt tctttccaat      960

cttcagacat tagacttaag aaacaatgaa atttcatggg ccatagaaga tgctagtgaa     1020

gcctttgctg gactcacaag tctcactaaa ctaatcttac aaggaaacca gattaagtca     1080

attacaaaga aagcattcat tggtcttgaa tcccttgagc atctagattt gaacaataat     1140

gctataatgt ctatccaaga aaatgctttt tctcagactc atttaaaaga actgattctg     1200

aacacaagca gtttgctctg tgactgccat ttgaagtggc tacttcaatg gttggttgat     1260

aataactttc aacattctgt gaatgtaagc tgtgcacacc ctgaatggct agcagggcaa     1320

agcatcctga atgtggatct gaaagatttt gtctgtgatg attttctcaa gccacagata     1380

aggacacatc ctgaaaccat aattgctcta agaggcatga atgtgactct gacgtgcact     1440

gcagtgagca gcagtgattc acccatgtcc actgtgtggc gcaaagacag tgaaatcctg     1500

tatgacgtgg atactgagaa ttttgttcgt tattggcagc aagctggaga agctctggaa     1560

tatactagta tcttacatct tttcaatgtg aatttcacag atgaaggaaa atatcagtgt     1620

attgttacta atcactttgg ttctaattat tctcagaaag ccaaactgac tgtaaatgag     1680

atgccatctt ttctgaaaac gccaatggat ctgactattc gcactggtgc catggccaga     1740

ttagaatgtg ctgcagaggg acaccctgca cctcagattt cctggcagaa agatggtggt     1800

actgactttc ctgcggctcg agaaagacgc atgcacgtca tgcccgagga tgacgtcttc     1860

tttattgcca atgtgaaaat agaagatatg ggaatctata gctgcatggc acaaaataca     1920

gcaggaggtc tctcagcaaa tgcttcccta acagtgttag agacaccctc atttattaga     1980

cccctggagg ataagacagt aacccgaggt gaaactgcgg tgttacagtg catagctgga     2040

gggagtcctg cccctcgtct caactggact aaagatgatg ggcctttgct ggtgacagaa     2100

cgacatttct ttgctgcagc caatcagctt ctcatcattg tagatgccgg gctagaagat     2160

gctgggaaat atacctgcat tatgtctaac acccttggga cagaacgtgg ccacatttac     2220

ctaaatgtca tttcatcccc caattgtgac tcttcccaga gtagcattgg gcatgaagat     2280

gatggctgga ccacagttgg c                                               2301


<210>  3937
<211>  2355
<212>  DNA
<213>  Homo Sapiens

<400>  3937
ggccggtccg acagcggcgg tcgcggggaa ctcgggcagc cctctggggt agccgccgag       60

cgcccatgcc ccactacctg ccgctgcctc ggggacctgc tggactgcag tcgtaagcgg      120

ctagcgcgtc ttcccgagcc actcccgtcc tgggtcgctc ggctggactt aagtcacaac      180

agattatctt tcatcaaggc aagttccatg agccaccttc aaagccttcg agaagtgaaa      240

ctgaacaaca atgaattgga gaccattcca aatctgggac cagtctcggc aaatattaca      300

cttctctcct tggctggaaa caggattgtt gaaatactcc ctgaacatct gaaagagttt      360

cagtcccttg aaactttgga ccttagcagc aacaatattt cagagctcca aactgcattt      420

ccagccctac agctcaaata tctgtatctc aacagcaacc gagtcacatc aatggaacct      480

gggtattttg acaatttggc caacacactc cttgtgttaa agctgaacag gaaccgaatc      540

tcagctatcc cacccaagat gtttaaactg ccccaactgc aacatctcga attgaaccga      600

aacaagatta aaaatgtaga tggactgaca ttccaaggcc ttggtgctct gaagtctctg      660

aaaatgcaaa gaaatggagt aacgaaactt atggatggag ctttttgggg gctgagcaac      720

atggaaattt tgcagctgga ccataacaac ctaacagaga ttaccaaagg ctggctttac      780

ggcttgctga tgctgcagga acttcatctc agccaaaatg ccatcaacag gatcagccct      840

gatgcctggg agttctgcca gaagctcagt gagctggacc taactttcaa tcacttatca      900

aggttagatg attcaagctt ccttggccta agcttactaa atacactgca cattgggaac      960

aacagagtca gctacattgc tgattgtgcc ttccgggggc tttccagttt aaagactttg     1020

gatctgaaga acaatgaaat ttcctggact attgaagaca tgaatggtgc tttctctggg     1080

cttgacaaac tgaggcgact gatactccaa ggaaatcgga tccgttctat tactaaaaaa     1140

gccttcactg gtttggatgc attggagcat ctagacctga gtgacaacgc aatcatgtct     1200

ttacaaggca atgcattttc acaaatgaag aaactgcaac aattgcattt aaatacatca     1260

agccttttgt gcgattgcca gctaaaatgg ctcccacagt gggtggcgga aaacaacttt     1320

cagagctttg taaatgccag ttgtgcccat cctcagctgc taaaaggaag aagcattttt     1380

gctgttagcc cagatggctt tgtgtgtgat gattttccca aaccccagat cacggttcag     1440

ccagaaacac agtcggcaat aaaaggttcc aatttgagtt tcatctgctc agctgccagc     1500

agcagtgatt ccccaatgac ttttgcttgg aaaaaagaca atgaactact gcatgatgct     1560

gaaatggaaa attatgcaca cctccgggcc caaggtggcg aggtgatgga gtataccacc     1620

atccttcggc tgcgcgaggt ggaatttgcc agtgagggga aatatcagtg tgtcatctcc     1680

aatcactttg gttcatccta ctctgtcaaa gccaagctta cagtaaatat gcttccctca     1740

ttcaccaaga cccccatgga tctcaccatc cgagctgggg ccatggcacg cttggagtgt     1800

gctgctgtgg ggcacccagc cccccagata gcctggcaga aggatggggg cacagacttc     1860

ccagctgcac gggagagacg catgcatgtg atgcccgagg atgacgtgtt ctttatcgtg     1920

gatgtgaaga tagaggacat tggggtatac agctgcacag ctcagaacag tgcaggaagt     1980

atttcagcaa atgcaactct gactgtccta gaaacaccat catttttgcg gccactgttg     2040

gaccgaactg taaccaaggg agaaacagcc gtcctacagt gcattgctgg aggaagccct     2100

ccccctaaac tgaactggac caaagatgat agcccattgg tggtaaccga gaggcacttt     2160

tttgcagcag gcaatcagct tctgattatt gtggactcag atgtcagtga tgctgggaaa     2220

tacacatgtg agatgtctaa cacccttggc actgagagag gaaacgtgcg cctcagtgtg     2280

atccccactc caacctgcga ctcccctcag atgacagccc catcgttaga cgatgacgga     2340

tgggccactg tgggt                                                      2355


<210>  3938
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  3938
gctcagcctt tctgtctgcc aggatgcact tgctcagagg agagttttgg caggactctg       60

cagtgcacat ctgtctcctt gggaaagatc cctgggaacc tttctgaaga gttcaagcaa      120

gtgagaattg aaaattcacc cttatttgag atgccccaag ggtctttcat caacatgagc      180

accttggaat acctctggct caattttaac aatatcagtg tgatccacct aggagccctg      240

gaacacctgc cagaactgag ggagctgaga ctggagggga acaagctctg ctcagtacca      300

tggacagcgt tccgtgccac ccctctcctg agggtcttgg atctcaaacg caacaagatt      360

gatgcactcc ctgagctggc tcttcaattc ttggtcagcc tgacctacct tgacctatcc      420

tccaataggc ttacagttgt atccaagagt gtcttcctga actggccagc ctaccagaaa      480

tgccggcagc ctgactgtgg ggctgagatt ctctccagcc tggtggtggc cctgcatgac      540

aacccctggg tatgtgactg tcgcctaagg gggcttgtcc agtttgtcaa gtccattacc      600

ctcccagtca tcctggtgaa ttcctacctg atatgtcagg gccctctgtc caaggcaggg      660

cagctttttc atgaaactga gcttagtgct tgcatgaagc cacagatctc aacccccagt      720

gccaatatca ccatccgggc aggacagaat gtgaccctgc gatgcttggc acaggccagc      780

ccctcaccat ccattgcatg gacttatccc ctgagtatgt ggagagaatt tgatggattg      840

ctgggaggca aacacctgac accagtgttg acatcttcta ctggagaaga cactgctctg      900

tcagagctgg ccatacctgc tgcccacctg gtagacagtg gtaattacac ctgcatggcc      960

tccaactcca ttggcaagag caaccttgta atctctctcc atgtccagcc tgcccaggcc     1020

ctacatgcac ctgattctct ttccatcccc tcggagggca atgcctacat tgacctgcgg     1080

gttgtcaagc agacagtgca tgggattttg ctggagtggc ttgcagtggc tgacacctct     1140

aaggaggagt ggttcaccct ctacattgca tcggatgaag ccttcaggaa ggaggtggtt     1200

cacattggcc ccggaatcaa tacttatgct gtggatgacc tccttcctgg cacaaaatat     1260

gaggcctgcc tcagcctaga gggccagcct ccacaccagg gccagtgtgt agcttttgta     1320

acaggcagag atgctggtgg gctagaggca cgtgagcacc tcctgcat                  1368


<210>  3939
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  3939
ccatcagtga tgacctcagc caccaaaatc atgtctgctc tgggcagtaa tgttctactg       60

cggtgtgatg ccactggctt ccccacccca cagatcacat ggaccagatc tgacagctcg      120

ccagttaatt atacagtaat acaagaatct ccagaggaag gagtcagatg gtccataatg      180

agcttgacag gcatttcttc caaagacgct ggggattaca aatgtaaggc caaaaatctg      240

gctgggatgt cagaagctgt ggttactgtg acagtgcttg gcattaccac aactccaata      300

ccaccagaca cttctgaaag aactggagat catcctgagt gggatgtcca gccgggatct      360

ggaagatcta catctgtatc tagcgcatca tcatatcttt ggtcctcttc cttctccccc      420

acatcttctt tttctgcttc tactttgtct cctccctcta ctgcttcctt ctctttatct      480

cctttctcct cctccactgt ttcttcaacc acaactctga gcacaagcat ctcagcaagt      540

accaccatgg ccaacaagcg atcattccag ctccaccaag gtgggaaaag aaatttaaag      600

gtggcaaaga atggaagtaa gcttcctcca gccagcacaa gtaagaaaga agagctggca      660

ttgttggatc aaacaatgct tacggagaca aatgccacaa tagaaaacct cagggtggtc      720

agtgagacta aagagagtgt gacattgatg tggaatatga tcaacaccac acataactct      780

gcagtgactg tgttgtattc caagtatggt gggaaggacc tgctgctgtt gaatgcagac      840

tccagcaaga accaagtaac catagatggc ttggaacctg gtgggcaata catggcctgt      900

gtctgtccaa aaggagtgcc tccccagaaa gaccaatgca tcaccttttc tactgaaaga      960

gttgaaggag atgattctca atggtct                                          987


<210>  3940
<211>  1239
<212>  DNA
<213>  Homo Sapiens

<400>  3940
gccttgccgc ccgcggcgcc gctgtccgaa ctgcacgcgc agctgtcggg cgtggagcag       60

ctgctggagg agttccgccg gcaactgcag caggagcggc ctcaggagga gctggagctg      120

gagctgcgcg cgggcggcgg cccccaggag gactgcccag gccggggcag cggcggctac      180

agcgcaatgc ctgacgccat catccgcacc aaggactccc tggcggcggg tgccagcttc      240

ctgcgggcgc cggcggccgt gcggggctgg cggcaatgcg tggcggcctg ctgctccgag      300

ccgcgctgct ccgtggccgt ggtggagctg ccccggcgcc ccgcgccccc ggcagccgtg      360

ctcggctgct acctcttcaa ctgcacggcg cgcggccgca acgtctgcaa gttcgcgctg      420

cacagcggct acagcagcta cagcctcagc cgcgcgccgg acggcgccgc cctggccacc      480

gcgcgcgcct cgccccggca ggaaaaggat gcgcctccac ttagcaaggc tgggcaggat      540

gtggttctgc atctgcccac agacggggtg gttctagacg gccgcgagag cacagatgac      600

cacgccatcg tccagtatga gtgggcactg ctgcaggggg acccgtcagt ggacatgaag      660

gtgcctcaat caggaaccct gaagctgtcc cacctacagg agggaaccta caccttccag      720

ctgaccgtga cggacactgc cgggcagaga agctctgaca acgtgtcagt gacagtgctt      780

cgcgcagcct actccacagg aggatgtttg cacacttgct cacgctacca cttcttctgt      840

gacgatggct gctgcattga catcacgctc gcctgcgatg gagtgcagca gtgtcctgat      900

gggtctgatg aagacttctg ccagaatctg ggcctggacc acaagatggt aacccacacg      960

gcagctagtc ctgccctgcc aagaaccaca gggccgagtg aagatgcagg gggtgactcc     1020

ttggtggaaa agtctcagaa agccactgcc ccaaacaagc cacctgcatt atcaaacaca     1080

gagaagagga atcattccgc cttttgggga ccagagagtc aaatcattcc tgtgatgcca     1140

gatagtagtt cctcagggaa gaacagaaaa gaggaaagtt atatatttga gtcaaagggt     1200

gatggaggag gaggggaaca cccagcccca gaaacaggt                            1239


<210>  3941
<211>  5115
<212>  DNA
<213>  Homo Sapiens

<400>  3941
agcagccccg agtgtgcttg tggtcggagc cacttcacat gtgcagtgag tgctcttgga       60

gagtgtacct gcatccctgc ccagtggcag tgtgatggag acaatgactg cggggaccac      120

agcgatgagg atggatgtat actacctacc tgttcccctc ttgactttca ctgtgacaat      180

ggcaagtgca tccgccgctc ctgggtgtgt gacggggaca acgactgtga ggatgactcg      240

gatgagcagg actgtccccc ccgggagtgt gaggaggacg agtttccctg ccagaatggc      300

tactgcatcc ggagtctgtg gcactgcgat ggtgacaatg actgtggcga caacagcgat      360

gagcagtgtg acatgcgcaa gtgctccgac aaggagttcc gctgtagtga cggaagctgc      420

attgctgagc attggtactg cgacggtgac accgactgca aagatggctc cgatgaggag      480

aactgtccct cagcagtgcc agcgcccccc tgcaacctgg aggagttcca gtgtgcctat      540

ggacgctgca tcctcgacat ctaccactgc gatggcgacg atgactgtgg agactggtca      600

gacgagtctg actgctcctc ccaccagccc tgccgctctg gggagttcat gtgtgacagt      660

ggcctgtgca tcaatgcagg ctggcgctgc gatggtgacg cggactgtga tgaccagtct      720

gatgagcgca actgcaccac ctccatgtgt acggcagaac agttccgctg tcactcaggc      780

cgctgtgtcc gcctgtcctg gcgctgtgat ggggaggacg actgtgcaga caacagcgat      840

gaagagaact gtgagaatac aggaagcccc caatgtgcct tggaccagtt cctgtgttgg      900

aatgggcgct gcattgggca gaggaagctg tgcaacgggg tcaacgactg tggtgacaac      960

agcgacgaaa gcccacagca gaattgccgg ccccggacgg gtgaggagaa ctgcaatgtt     1020

aacaacggtg gctgtgccca gaagtgccag atggtgcggg gggcagtgca gtgtacctgc     1080

cacacaggct accggctcac agaggatggg cacacgtgcc aagatgtgaa tgaatgtgcc     1140

gaggaggggt attgcagcca gggctgcacc aacagcgaag gggctttcca atgctggtgt     1200

gaaacaggct atgaactacg gcccgaccgg cgcagctgca aggctctggg gccagagcct     1260

gtgctgctgt tcgccaatcg catcgacatc cggcaggtgc tgccacaccg ctctgagtac     1320

acactgctgc ttaacaacct ggagaatgcc attgcccttg atttccacca ccgccgcgag     1380

cttgtcttct ggtcagatgt caccctggac cggatcctcc gtgccaacct caacggcagc     1440

aacgtggagg aggttgtgtc tactgggctg gagagcccag ggggcctggc tgtggattgg     1500

gtccatgaca aactctactg gaccgactca ggcacctcga ggattgaggt ggccaatctg     1560

gacggggccc accggaaggt gttgctgtgg cagaacctgg agaagccccg ggccattgcc     1620

ttgcatccca tggagggtac catttactgg acagactggg gcaacacccc ccgtattgag     1680

gcctccagca tggatggctc tggacgccgc atcattgccg atacccatct cttctggccc     1740

aatggcctca ccatcgacta tgccgggcgc cgtatgtact gggtggatgc taagcaccat     1800

gtcatcgaga gggccaatct ggatgggagt caccgtaagg ctgtcattag ccagggcctc     1860

ccgcatccct tcgccatcac agtgtttgaa gacagcctgt actggacaga ctggcacacc     1920

aagagcatca atagcgctaa caaatttacg gggaagaacc aggaaatcat tcgcaacaaa     1980

ctccacttcc ctatggacat ccacaccttg cacccccagc gccaacctgc agggaaaaac     2040

cgctgtgggg acaacaacgg aggctgcacg cacctgtgtc tgcccagtgg ccagaactac     2100

acctgtgcct gccccactgg cttccgcaag atcagcagcc acgcctgtgc ccagagtctt     2160

gacaagttcc tgctttttgc ccgaaggatg gacatccgtc gaatcagctt tgacacagag     2220

gacctgtctg atgatgtcat cccactggct gacgtgcgca gtgctgtggc ccttgactgg     2280

gactcccggg atgaccacgt gtactggaca gatgtcagca ctgataccat cagcagggcc     2340

aagtgggatg gaacaggaca ggaggtggta gtggatacca gtttggagag cccagctggc     2400

ctggccattg attgggtcac caacaaactg tactggacag atgcaggtac agaccggatt     2460

gaagtagcca acacagatgg cagcatgaga acagtactca tctgggagaa ccttgatcgt     2520

cctcgggaca tcgtggtgga acccatgggc gggtacatgt attggactga ctggggtgcg     2580

agccccaaga ttgaacgagc tggcatggat gcctcaggcc gccaagtcat tatctcttct     2640

aatctgacct ggcctaatgg gttagctatt gattatgggt cccagcgtct atactgggct     2700

gacgccggca tgaagacaat tgaatttgct ggactggatg gcagtaagag gaaggtgctg     2760

attggaagcc agctccccca cccatttggg ctgaccctct atggagagcg catctattgg     2820

actgactggc agaccaagag catacagagc gctgaccggc tgacagggct ggaccgggag     2880

actctgcagg agaacctgga aaacctaatg gacatccatg tcttccaccg ccgccggccc     2940

ccagtgtcta caccatgtgc tatggagaat ggcggctgta gccacctgtg tcttaggtcc     3000

ccaaatccaa gcggattcag ctgtacctgc cccacaggca tcaacctgct gtctgatggc     3060

aagacctgct caccaggcat gaacagtttc ctcatcttcg ccaggaggat agacattcgc     3120

atggtctccc tggacatccc ttattttgct gatgtggtgg taccaatcaa cattaccatg     3180

aagaacacca ttgccgttgg agtagacccc caggaaggaa aggtgtactg gtctgacagc     3240

acactgcaca ggatcagtcg tgccaatctg gatggctcac agcatgagga catcatcacc     3300

acagggctac agaccacaga tgggctcgcg gttgatgcca ttggccggaa agtatactgg     3360

acagacacgg gaacaaaccg gattgaagtg ggcaacctgg acgggtccat gcggaaagtg     3420

ttggtgtggc agaaccttga cagtccccgg gccatcgtac tgtaccatga gatggggttt     3480

atgtactgga cagactgggg ggagaatgcc aagttagagc ggtccggaat ggatggctca     3540

gaccgcgcgg tgctcatcaa caacaaccta ggatggccca atggactgac tgtggacaag     3600

gccagctccc aactgctatg ggccgatgcc cacaccgagc gaattgaggc tgctgacctg     3660

aatggtgcca atcggcatac attggtgtca ccggtgcagc acccatatgg cctcaccctg     3720

ctcgactcct atatctactg gactgactgg cagactcgga gcatccaccg tgctgacaag     3780

ggtactggca gcaatgtcat cctcgtgagg tccaacctgc caggcctcat ggacatgcag     3840

gctgtggacc gggcacagcc actaggtttt aacaagtgcg gctcgagaaa tggcggctgc     3900

tcccacctct gcttgcctcg gccttctggc ttctcctgtg cctgccccac tggcatccag     3960

ctgaagggag atgggaagac ctgtgatccc tctcctgaga cctacctgct cttctccagc     4020

cgtggctcca tccggcgtat ctcactggac accagtgacc acaccgatgt gcatgtccct     4080

gttcctgagc tcaacaatgt catctccctg gactatgaca gcgtggatgg aaaggtctat     4140

tacacagatg tgttcctgga tgttatcagg cgagcagacc tgaacggcag caacatggag     4200

acagtgatcg ggcgagggct gaagaccact gacgggctgg cagtggactg ggtggccagg     4260

aacctgtact ggacagacac aggtcgaaat accattgagg cgtccaggct ggatggttcc     4320

tgccgcaaag tactgatcaa caatagcctg gatgagcccc gggccattgc tgttttcccc     4380

aggaaggggt acctcttctg gacagactgg ggccacattg ccaagatcga acgggcaaac     4440

ttggatggtt ctgagcggaa ggtcctcatc aacacagacc tgggttggcc caatggcctt     4500

accctggact atgatacccg caggatctac tgggtggatg cgcatctgga ccggatcgag     4560

agtgctgacc tcaatgggaa actgcggcag gtcttggtcg gccatgtgtc ccaccccttt     4620

gccctcacac agcaagacag gtggatctac tggacagact ggcagaccaa gtcaatccag     4680

cgtgttgaca aatactcagg ccggaacaag gagacagtgc tggcaaatgt ggaaggactc     4740

atggatatca tcgtggtttc ccctcagcgg cagacaggga ccaatgcctg tggtgtgaac     4800

aatggtggct gcacccacct ctgctttgcc agagcctcgg acttcgtatg tgcctgtcct     4860

gacgaacctg atagccagcc ctgctccctt gtgcctggcc tggtaccacc agctcctagg     4920

gctactggca tgagtgaaaa gagcccagtg ctacccaaca caccacctac caccttgtat     4980

tcttcaacca cccggacccg cacgtctctg gaggaggtgg aaggaagatg ctctgaaagg     5040

gatgccaggc tgggcctctg tgcacgttcc aatgacgctg ttcctgctgc tccaggggaa     5100

ggacttcata tcagc                                                      5115


<210>  3942
<211>  2223
<212>  DNA
<213>  Homo Sapiens

<400>  3942
gaggccttct tggtcttcac cagcagagcc gccatccaca ggatctccct cgagaccaat       60

aacaacgacg tggccatccc gctcacgggc gtcaaggagg cctcagccct ggactttgat      120

gtgtccaaca accacatcta ctggacagac gtcagcctga agaccatcag ccgcgccttc      180

atgaacggga gctcggtgga gcacgtggtg gagtttggcc ttgactaccc cgagggcatg      240

gccgttgact ggatgggcaa gaacctctac tgggccgaca ctgggaccaa cagaatcgaa      300

gtggcgcggc tggacgggca gttccggcaa gtcctcgtgt ggagggactt ggacaacccg      360

aggtcgctgg ccctggatcc caccaagggc tacatctact ggaccgagtg gggcggcaag      420

ccgaggatcg tgcgggcctt catggacggg accaactgca tgacgctggt ggacaaggtg      480

ggccgggcca acgacctcac cattgactac gctgaccagc gcctctactg gaccgacctg      540

gacaccaaca tgatcgagtc gtccaacatg ctgggtcagg agcgggtcgt gattgccgac      600

gatctcccgc acccgttcgg tctgacgcag tacagcgatt atatctactg gacagactgg      660

aatctgcaca gcattgagcg ggccgacaag actagcggcc ggaaccgcac cctcatccag      720

ggccacctgg acttcgtgat ggacatcctg gtgttccact cctcccgcca ggatggcctc      780

aatgactgta tgcacaacaa cgggcagtgt gggcagctgt gccttgccat ccccggcggc      840

caccgctgcg gctgcgcctc acactacacc ctggacccca gcagccgcaa ctgcagcccg      900

cccaccacct tcttgctgtt cagccagaaa tctgccatca gtcggatgat cccggacgac      960

cagcacagcc cggatctcat cctgcccctg catggactga ggaacgtcaa agccatcgac     1020

tatgacccac tggacaagtt catctactgg gtggatgggc gccagaacat caagcgagcc     1080

aaggacgacg ggacccagcc ctttgttttg acctctctga gccaaggcca aaacccagac     1140

aggcagcccc acgacctcag catcgacatc tacagccgga cactgttctg gacgtgcgag     1200

gccaccaata ccatcaacgt ccacaggctg agcggggaag ccatgggggt ggtgctgcgt     1260

ggggaccgcg acaagcccag ggccatcgtc gtcaacgcgg agcgagggta cctgtacttc     1320

accaacatgc aggaccgggc agccaagatc gaacgcgcag ccctggacgg caccgagcgc     1380

gaggtcctct tcaccaccgg cctcatccgc cctgtggccc tggtggtaga caacacactg     1440

ggcaagctgt tctgggtgga cgcggacctg aagcgcattg agagctgtga cctgtcaggg     1500

gccaaccgcc tgaccctgga ggacgccaac atcgtgcagc ctctgggcct gaccatcctt     1560

ggcaagcatc tctactggat cgaccgccag cagcagatga tcgagcgtgt ggagaagacc     1620

accggggaca agcggactcg catccagggc cgtgtcgccc acctcactgg catccatgca     1680

gtggaggaag tcagcctgga ggagttctca gcccacccat gtgcccgtga caatggtggc     1740

tgctcccaca tctgtattgc caagggtgat gggacaccac ggtgctcatg cccagtccac     1800

ctcgtgctcc tgcagaacct gctgacctgt ggagagccgc ccacctgctc cccggaccag     1860

tttgcatgtg ccacagggga gatcgactgt atccccgggg cctggcgctg tgacggcttt     1920

cccgagtgcg atgaccagag cgacgaggag ggctgccccg tgtgctccgc cgcccagttc     1980

ccctgcgcgc ggggtcagtg tgtggacctg cgcctgcgct gcgacggcga ggcagactgt     2040

caggaccgct cagacgaggc ggactgtgac gccatctgcc tgcccaacca gttccggtgt     2100

gcgagcggcc agtgtgtcct catcaaacag cagtgcgact ccttccccga ctgtatcgac     2160

ggctccgacg agctcatgtg tgaaatcacc aagccgccct cagacgacag cccggcccac     2220

agc                                                                   2223


<210>  3943
<211>  4053
<212>  DNA
<213>  Homo Sapiens

<400>  3943
gcccctttgt tgctttatgc aaacagacgg gacttgcgat tggttgatgc tacaaatggc       60

aaagagaatg ctacgattgt agttggaggc ttggaggatg cagctgcggt ggactttgtg      120

tttagtcatg gcttgatata ctggagtgat gtcagcgaag aagccattaa acgaacagaa      180

tttaacaaaa ctgagagtgt gcagaatgtt gttgtttctg gattattgtc ccccgatggg      240

ctggcatgtg attggcttgg agaaaaattg tactggacag attctgaaac taatcggatt      300

gaagtttcta atttagatgg atctttacga aaagttttat tttggcaaga gttggatcaa      360

cccagagcta ttgccttaga tccttcaagt gggttcatgt actggacaga ctggggagaa      420

gtgccaaaga tagaacgtgc tggaatggat ggttcaagtc gcttcattat aataaacagt      480

gaaatttact ggccaaatgg actgactttg gattatgaag aacaaaagct ttattgggca      540

gatgcaaaac ttaatttcat ccacaaatca aatctggatg gaacaaatcg gcaggcagtg      600

gttaaaggtt cccttccaca tccttttgcc ttgacgttat ttgaggacat attgtactgg      660

actgactgga gcacacactc cattttggct tgcaacaagt atactggtga gggtctgcgt      720

gaaatccatt ctgacatctt ctctcccatg gatatacatg ccttcagcca acagaggcag      780

ccaaatgcca caaatccatg tggaattgac aatgggggtt gttcccattt gtgtttgatg      840

tctccagtca agccttttta tcagtgtgct tgccccactg gggtcaaact cctggagaat      900

ggaaaaacct gcaaagatgg tgccacagaa ttattgcttt tagctcgaag gacagacttg      960

agacgcattt ctttggatac accagatttt acagacattg ttctgcagtt agaagacatc     1020

cgtcatgcca ttgccataga ttacgatcct gtggaaggct acatctactg gactgatgat     1080

gaagtgaggg ccatacgccg ttcatttata gatggatctg gcagtcagtt tgtggtcact     1140

gctcaaattg cccatcctga tggtattgct gtggactggg ttgcacgaaa tctttattgg     1200

acagacactg gcactgatcg aatagaagtg acaaggctca atgggaccat gaggaagatc     1260

ttgatttcag aggacttaga ggaaccccgg gctattgtgt tagatcccat ggttgggtac     1320

atgtattgga ctgactgggg agaaattccg aaaattgagc gagcagctct ggatggttct     1380

gaccgtgtag tattggttaa cacttctctt ggttggccaa atggtttagc cttggattat     1440

gatgaaggca aaatatactg gggagatgcc aaaacagaca agattgaggt tatgaatact     1500

gatggcactg ggagacgagt actagtggaa gacaaaattc ctcacatatt tggatttact     1560

ttgttgggtg actatgttta ctggactgac tggcagaggc gtagcattga aagagttcat     1620

aaacgaagtg cagagaggga agtgatcata gatcagctgc ctgacctcat gggcctaaag     1680

gctacaaatg ttcatcgagt gattggttcc aacccctgtg ctgaggaaaa cgggggatgt     1740

agccatctct gcctctatag acctcagggc cttcgctgtg cttgccctat tggctttgaa     1800

ctcatcagtg acatgaagac ctgcattgtc ccagaggctt tccttttgtt ttcacggaga     1860

gcagatatca gacgaatttc tctggaaaca aacaataata atgtggctat tccactcact     1920

ggtgtcaaag aagcttctgc tttggatttt gatgtgacag acaaccgaat ttattggact     1980

gatatatcac tcaagaccat cagcagagcc tttatgaatg gcagtgcact ggaacatgtg     2040

gtagaattcg gcttagatta tccagaaggc atggcagtag actggcttgg gaagaacttg     2100

tactgggcag acacaggaac gaatcgaatt gaggtgtcaa agttggatgg gcagcaccga     2160

caagttttgg tgtggaaaga cctagatagt cccagagctc tcgcgttgga ccctgccgaa     2220

ggatttatgt attggactga atggggtgga aaacctaaga tagacagagc tgcaatggat     2280

ggaagtgaac gtactacctt agttccaaat gtggggcggg caaacggcct aactattgat     2340

tatgctaaaa ggaggcttta ttggacagac ctggacacca acttaataga atcttcaaat     2400

atgcttgggc tcaaccgtga agttatagca gatgacttgc ctcatccttt tggcttaact     2460

cagtaccaag attatatcta ctggacggac tggagccgac gcagcattga gcgtgccaac     2520

aaaaccagtg gccaaaaccg caccatcatt cagggccatt tggattatgt gatggacatc     2580

ctcgtctttc actcatctcg acagtcaggg tggaatgaat gtgcttccag caatgggcac     2640

tgctcccacc tctgcttggc tgtgccagtt gggggttttg tttgtggatg ccctgcccac     2700

tactctctta atgctgacaa caggacttgt agtgctccta cgactttcct gctcttcagt     2760

caaaagagtg ccatcaaccg catggtgatt gatgaacaac agagccccga catcatcctt     2820

cccatccaca gccttcggaa tgtccgggcc attgactatg acccactgga caagcaactc     2880

tattggattg actcacgaca aaacatgatc cgaaaggcac aagaagatgg cagccagggc     2940

tttactgtgg ttgtgagctc agttccgagt cagaacctgg aaatacaacc ctatgacctc     3000

agcattgata tttacagccg ctacatctac tggacttgtg aggctaccaa tgtcattaat     3060

gtgacaagat tagatgggag atcagttgga gtggtgctga aaggcgagca ggacagacct     3120

cgagccgttg tggtaaaccc agagaaaggg tatatgtatt ttaccaatct tcaggaaagg     3180

tctcctaaaa ttgaacgggc tgctttggat gggacagaac gggaggtcct ctttttcagt     3240

ggcttaagta aaccaattgc tttagccctt gatagcaggc tgggcaagct cttttgggct     3300

gattcagatc tccggcgaat tgaaagcagt gatctctcag gtgctaaccg gatagtatta     3360

gaagactcca atatcttgca gcctgtggga cttactgtgt ttgaaaactg gctctattgg     3420

attgataaac agcagcaaat gattgaaaaa attgacatga caggtcgaga gggtagaacc     3480

aaagtccaag ctcgaattgc ccagcttagt gacattcatg cagtaaagga gctgaacctt     3540

caagaataca gacagcaccc ttgtgctcag gataatggtg gctgttcaca tatttgtctt     3600

gtaaaggggg atggtactac aaggtgttct tgccccatgc acctggttct acttcaagat     3660

gagctatcat gtggagaacc tccaacatgt tctcctcagc agtttacttg tttcacgggg     3720

gaaattgact gtatccctgt ggcttggcgg tgcgatgggt ttactgaatg tgaagaccac     3780

agtgatgaac tcaattgtcc tgtatgctca gagtcccagt tccagtgtgc cagtgggcag     3840

tgtattgatg gtgccctccg atgcaatgga gatgcaaact gccaggacaa atcagatgag     3900

aagaactgtg aagtgctttg tttaattgat cagttccgct gtgccaatgg tcagtgcatt     3960

ggaaagcaca agaagtgtga tcataatgtg gattgcagtg acaagtcaga tgaactggat     4020

tgttatccga ctgaagaacc agcaccacag gcc                                  4053


<210>  3944
<211>  2355
<212>  DNA
<213>  Homo Sapiens

<400>  3944
gggccggcca aggagtgcga aaaggaccaa ttccagtgcc ggaacgagcg ctgcatcccc       60

tctgtgtgga gatgcgacga ggacgatgac tgcttagacc acagcgacga ggacgactgc      120

cccaagaaga cctgtgcaga cagtgacttc acctgtgaca acggccactg catccacgaa      180

cggtggaagt gtgacggcga ggaggagtgt cctgatggct ccgatgagtc cgaggccact      240

tgcaccaagc aggtgtgtcc tgcagagaag ctgagctgtg gacccaccag ccacaagtgt      300

gtacctgcct cgtggcgctg cgacggggag aaggactgcg agggtggagc ggatgaggcc      360

ggctgtgcta ccttgtgcgc cccgcacgag ttccagtgcg gcaaccgctc gtgcctggcc      420

gccgtgttcg tgtgcgacgg cgacgacgac tgtggtgacg gcagcgatga gcgcggctgt      480

gcagacccgg cctgcgggcc ccgcgagttc cgctgcggcg gcgatggcgg cggcgcctgc      540

atcccggagc gctgggtctg cgaccgccag tttgactgcg aggaccgctc ggacgaggca      600

gccgagctct gcggccgtcc gggccccggg gccacgtccg cgcccgccgc ctgcgccacc      660

gcctcccagt tcgcctgccg cagcggcgag tgcgtgcacc tgggctggcg ctgcgacggc      720

gaccgcgact gcaaagacaa atcggacgag gccgactgcc cactgggcac ctgccgtggg      780

gacgagttcc agtgtgggga tgggacatgt gtccttgcaa tcaagcactg caaccaggag      840

caggactgtc cagatgggag tgatgaagct ggctgcctac aggggctgaa cgagtgtctg      900

cacaacaatg gcggctgctc acacatctgc actgacctca agattggctt tgaatgcacg      960

tgcccagcag gcttccagct cctggaccag aagacctgtg gcgacattga tgagtgcaag     1020

gacccagatg cctgcagcca gatctgtgtc aattacaagg gctattttaa gtgtgagtgc     1080

taccctggct acgagatgga cctactgacc aagaactgca aggctgctgc tggcaagagc     1140

ccatccctaa tcttcaccaa ccggcacgag gtgcggagga tcgacctggt gaagcggaac     1200

tattcacgcc tcatccccat gctcaagaat gtcgtggcac tagatgtgga agttgccacc     1260

aatcgcatct actggtgtga cctctcctac cgtaagatct atagcgccta catggacaag     1320

gccagtgacc cgaaagagca ggaggtcctc attgacgagc agttgcactc tccagagggc     1380

ctggcagtgg actgggtcca caagcacatc tactggactg actcgggcaa taagaccatc     1440

tcagtggcca cagttgatgg tggccgccga cgcactctct tcagccgtaa cctcagtgaa     1500

ccccgggcca tcgctgttga ccccctgcga gggttcatgt attggtctga ctggggggac     1560

caggccaaga ttgagaaatc tgggctcaac ggtgtggacc ggcaaacact ggtgtcagac     1620

aatattgaat ggcccaacgg aatcaccctg gatctgctga gccagcgctt gtactgggta     1680

gactccaagc tacaccaact gtccagcatt gacttcagtg gaggcaacag aaagacgctg     1740

atctcctcca ctgacttcct gagccaccct tttgggatag ctgtgtttga ggacaaggtg     1800

ttctggacag acctggagaa cgaggccatt ttcagtgcaa atcggctcaa tggcctggaa     1860

atctccatcc tggctgagaa cctcaacaac ccacatgaca ttgtcatctt ccatgagctg     1920

aagcagccaa gagctccaga tgcctgtgag ctgagtgtcc agcctaatgg aggctgtgaa     1980

tacctgtgcc ttcctgctcc tcagatctcc agccactctc ccaagtacac atgtgcctgt     2040

cctgacacaa tgtggctggg tccagacatg aagaggtgct accgagcacc tcaatctacc     2100

tcaactacga cgttagcttc taccatgacg aggacagtac ctgccaccac aagagccccc     2160

gggaccaccg tccacagatc cacctaccag aaccacagca cagagacacc aagcctgaca     2220

gctgcagtcc caagctcagt tagtgtcccc agggctccca gcatcagccc gtctacccta     2280

agccctgcaa ccagcaacca ctcccagcac tatgcaaatg aagacagtaa gatgggctca     2340

acagtcactg ccgct                                                      2355


<210>  3945
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  3945
taccatggct gccctagcga gtgtacctgc tccagggcct cccaggtgga gtgcaccggg       60

gcacgcattg tggcagtgcc cacccctctg ccctggaacg ccatgagcct gcagatcctc      120

aacacgcaca tcactgaact caatgagtcc ccgttcctca atatctcagc cctcatcgcc      180

ctgaggattg agaagaatga gctgtcgcgc atcacgcctg gggccttccg aaacctgggc      240

tcgctgcgct atctcagcct cgccaacaac aagctgcagg ttctgcccat cggcctcttc      300

cagggcctgg acagcctcga gtctctcctt ctgtccagta accagctgtt gcagatccag      360

ccggcccact tctcccagtg cagcaacctc aaggagctgc agttgcacgg caaccacctg      420

gaatacatcc ctgacggagc cttcgaccac ctggtaggac tcacgaagct caatctgggc      480

aagaatagcc tcacccacat ctcacccagg gtcttccagc acctgggcaa cctccaggtc      540

ctccggctgt atgagaacag gctcacggat atccccatgg gcacttttga tgggcttgtt      600

aacctgcagg aactggctct gcagcagaac cagattggac tgctctcccc tggtctcttc      660

cacaacaacc acaacctcca gagactctac ctgtccaaca accacatctc ccagctgcca      720

cccagcgtct tcatgcagct gccccagctc aaccgtctta ctctctttgg gaattccctg      780

aaggagctct ctccggggat cttcgggccc atgcccaacc tgcgggagct ttggctctat      840

gacaaccaca tctcttctct acccgacaat gtcttcagca acctccgcca gttgcaggtc      900

ctgattctta gccgcaatca gatcagcttc atctccccgg gtgccttcaa cgggctaacg      960

gagcttcggg agctgtccct ccacaccaac gcactgcagg acctggacgg gaacgtcttc     1020

cgcatgttgg ccaacctgca gaacatctcc ctgcagaaca accgcctcag acagctccca     1080

gggaatatct tcgccaacgt caatggcctc atggccatcc agctgcagaa caaccagctg     1140

gagaacttgc ccctcggcat cttcgatcac ctggggaaac tgtgtgagct gcggctgtat     1200

gacaatccct ggaggtgtga ctcagacatc cttccgctcc gcaactggct cctgctcaac     1260

cagcctaggt tagggacgga cactgtacct gtgtgtttca gcccagccaa tgtccgaggc     1320

cagtccctca ttatcatcaa tgtcaacgtt gctgttccaa gcgtccatgt ccccgaggtg     1380

cctagttacc cagaaacacc atggtaccca gacacaccca gttaccctga caccacatcc     1440

gtctcttcta ccactgagct aaccagccct gtggaagact acactgatct gactaccatt     1500

caggtcactg atgaccgcag cgtttggggc atgacccagg cccagagcgg g              1551


<210>  3946
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  3946
cgcaaagcaa gcccaggcag tgtgagaagc cgagtgaatc atggccgggc gggtggaggc       60

cggagaggct ccaacccggt caaacgctac gcaccaggcc tcccgtgtga cgtgtacaca      120

tatctccatg agaaatactt agattgtcaa gaaagaaaat tagtttatgt gctgcctggt      180

tggcctcagg atttgctgca catgctgcta gcaagaaaca agatccgcac attgaagaac      240

aacatgtttt ccaagtttaa aaagctgaaa agcctggatc tgcagcagaa tgagatctct      300

aaaattgaga gtgaggcgtt ctttggttta aacaaactca ccaccctctt actgcagcac      360

aaccagatca aagtcttgac ggaggaagtg ttcatttaca cacctctctt gagctacctg      420

cgtctttatg acaacccctg gcactgtact tgtgagatag aaacgcttat ttcaatgttg      480

cagattccca ggaaccggaa tttggggaac tacgccaagt gtgaaagtcc acaagaacaa      540

aaaaataaaa aactgcggca gataaaatct gaacagttgt gtaatgaaga agaaaaggaa      600

caattggacc cgaaacccca agtgtcaggg agacccccag tcatcaagcc tgaggtggac      660

tcaacttttt gccacaatta tgtgtttccc atacaaacac tggactgcaa aaggaaagag      720

ttgaaaaaag tgccaaacaa catccctcca gatattgtta aacttgactt gtcatacaat      780

aaaatcaacc aacttcgacc caaggaattt gaagatgttc atgagctgaa gaaattaaac      840

ctcagcagca atggcattga attcatcgat cctgccgctt ttttagggct cacacattta      900

gaagaattag atttatcaaa caacagtctg caaaactttg actatggcgt attagaagac      960

ttgtattttt tgaaactctt gtggctcaga gataaccctt ggagatgtga ctacaacatt     1020

cactacctct actactggtt aaagcaccac tacaatgtcc attttaatgg cctggaatgc     1080

aaaacgcctg aagaatacaa aggatggtct gtgggaaaat atattagaag ttactatgaa     1140

gaatgcccca aagacaagtt accagcatat cctgagtcat ttgaccaaga cacagaagat     1200

gatgaatggg aaaaaaaaca tagagatcac accgcaaaga agcaaagcgt aataattact     1260

atagtagga                                                             1269


<210>  3947
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  3947
tctaaaagag aagtccaatg taattttact gaaaaaaatt ataccttgat tccagcagat       60

atcaagaaag atgttactat acttgatctc agttataacc aaattactct taatggtaca      120

gacacaagag ttctacagac atacttttta ctcacagagc tctatttgat tgagaacaag      180

gttactatct tacataataa cggttttggt aacctctcca gtctagaaat tttaaatatc      240

tgtagaaact ccatctatgt aattcaacag ggtgcatttt taggcttaaa taaactaaaa      300

cagttatatc tctgccaaaa caaaatagaa caactgaatg ctgatgtatt tgtgcctcta      360

agaagcctaa aacttctgaa tctgcaaggc aatttgatta gctatttgga tgtaccacca      420

ctatttcatc tggaattaat aactttatat ggaaacctat ggaactgctc ttgcagtcta      480

tttaatttgc agaactggtt gaacacatca aatgtgacat tagaaaatga gaacatcacc      540

atgtgtagct accccaacag cctgcagagc tacaatatca aaacagtacc tcataaggct      600

gaatgccact caaaatttcc ttcatcagta actgaagatc tttatattca ttttcagccc      660

atcagcaatt caatatttaa tagctcttcg aacaacttaa caagaaattc agaacatgaa      720

cctcttggaa aaagttgg                                                    738


<210>  3948
<211>  1515
<212>  DNA
<213>  Homo Sapiens

<400>  3948
ttctgcccct ctcaatgcag ctgcagcctc catatcatgg gtgatggcag caaggccagg       60

acagtagtgt gcaacgaccc cgacatgacc ctgcccccgg cgtccatccc cccggacacc      120

tccagactgc gcctggagcg gacggccata cgcagggttc ctggcgaggc cttcaggccc      180

ctgggccgcc tggagcagct gtggctgcct tacaacgccc tcagcgagct caacgccctc      240

atgctgcggg gcctgcgacg cctgcgggag ctgcggctgc ccgggaaccg cctggccgcc      300

ttcccctggg cggcgctcag ggacgccccc aagctgcggc tgctggacct gcaggccaac      360

cgcctctcgg ctgtgcccgc tgaggccgcg cgcttcctgg agaacctcac cttcctcgac      420

ctctccagca accagctgat gaggctcccg caggagctca tcgtctcctg ggctcacctg      480

gagaccggta tctttcctcc cggccaccac cccaggcggg tcctagggct acaggacaac      540

ccctgggcat gtgactgccg actctatgac ctggttcatc ttttggatgg ctgggcccca      600

aacttggcct tcattgagac tgaactgaga tgtgccagcc cacgtagcct ggccggagtg      660

gccttcagcc agcttgaact gaggaagtgc cagggcccag agctccatcc aggagtggcc      720

agcatcaggt cccttttggg tggcacagca ctgctacgct gtggagctac tggagtccct      780

gggcccgaga tgagctggag gagggccaat ggcaggcccc ttaatggtac agtgcaccag      840

gaagtctcca gtgacggcac gagctggact ctgctgggcc tgcctgcagt gtcccacctt      900

gactccggag actacatctg ccaagccaag aacttcctgg gagcctctga aactgttatc      960

tccttgattg tcactgagcc accgacttcc acagaacaca gtgggagccc aggagcacta     1020

tgggcaagga caggtggcgg aggggaagct gctgcttaca acaacaagct ggtggccagg     1080

catgtccccc agattcccaa acccgctgtc ctggccactg gaccctctgt gcccagcaca     1140

aaggaggagc tgacccttga gcacttccag atggatgccc tgggagagct ctctgatggg     1200

cgggcaggac cctcagaggc acgaatggtg aggtctgtga aggtggtggg ggacacttac     1260

cacagcgtgt ccttggtgtg gaaggcaccc caggctaaga acacaactgc cttcagtgtc     1320

ctctacgcgg tctttgggca gcacagcatg cggcgggtga ttgtgcagcc tgggaagacc     1380

agagtgacca tcactgggct gttgcccaag accaagtatg tggcgtgtgt ctgtgtgcag     1440

ggcctggtgc cccggaagga gcagtgtgtt attttctcca ccaatgaagt ggtggatgct     1500

gagaacactc agcag                                                      1515


<210>  3949
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  3949
gccggctgcc cagcagcctg ccgctgctac agcgccacgg tggagtgtgg cgccctgcgg       60

ttgcgcgtcg tcccgctggg aatcccgcca gggacgcaga cactgttcct gcaggacaac      120

aacatcgccc gcctagagcc gggagccctg gcgccactcg ccgctctgcg ccggctctac      180

ctgcacaaca acagcctgcg cgccctggag gccggcgcct tccgcgcgca gccgcgcctg      240

ctggagctgg cgctcactag caaccggctg cgcggcttgc gcagcggcgc cttcgtaggc      300

ctggcccagc tgcgcgtgct ctacctggcg ggcaaccagc tggcgcggct gctggatttc      360

accttcttgc acctgccgcg actgcaggag cttcacctgc aagaaaacag cattgagctg      420

ctggaggacc aggctctagc ggggctgtcc tccctagcac tgctggacct cagcaggaac      480

cagctgggca ccatcagccg agaggccctg cagcccctgg ccagtctgca agtcctgcgc      540

ctcacagaga acccatggcg ctgtgactgc gccctgcact ggctgggtgc ctggatcaag      600

gagggcggcc agcggctgct cacctccagg gacaggaaga tcatgtgtgc agagcccccg      660

cgcctggcgc tccagagtct cctggacgta tcccacagca gcctcatctg cattccgccc      720

tctgtccacg tgcagccgct ggagctcaca gccaacctgg gtgaggacct gcgggttgcc      780

tgccaagcct ccggctaccc gcagccattg gtgacctgga gaaaggtgcc ccagcctcgc      840

gagggccggc cgcgagccca ggcccagcta gaaggcgggt tgctgggcct gggcggacac      900

tcggcatccg acacgggcag cggcatgctc ttcctcagca acatcacgct ggcgcacgcc      960

ggtaagtacg agtgcgaggc ctccaacgcc ggcggcgctg cccgcgtgcc cttccggctc     1020

ctggtcaacg cgtcccggca gcagccgcag cagcccgcgc aaccgccgcc tccggccgcc     1080

cgccccgccg gcagcgagcc ccggcccgag gcgggcagca tggccttccg cgccctgggc     1140

gtggccacac agacg                                                      1155


<210>  3950
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  3950
ctagaaccgt cgtgcaccgt gtcctccgcg gatgtggact ggaacgcgga gttcagtgcc       60

acgtgcctga atttcagtgg cctcagcctg agcctgcctc acaaccagtc tctgcgggcc      120

agcaacgtga ttctccttga cctgtctggg aacggcctgc gagagcttcc agtgaccttc      180

tttgcccacc tgcagaagct tgaggtcctg aacgtgctac gcaacccctt gtctcgtgtg      240

gatggggcgc tggccgcccg ctgtgacctt gacctgcagg ccgactgcaa ctgtgccctg      300

gagtcctggc acgacatccg ccgagacaac tgctctggcc agaagcctct gctctgctgg      360

gacacaacca gctcccagca caacctctct gccttcctgg aggtcagctg cgcccctggc      420

ctggcctctg caact                                                       435


<210>  3951
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  3951
caggtctcag caaccgcgag cccatcaggc tctctaggcg cccctgattg ccctgaggta       60

tgtacgtgcg ttccgggggg tttagctagt tgtagtgcgc tgagcctacc tgccgtgccc      120

cctggcctaa gcctaagatt gcgtgcgctt ttgttagacc ataacagagt gagagccctg      180

ccgcccggtg ccttcgcagg cgccggggcg ctgcaaaggt tggatctgag ggagaacggg      240

cttcattcag tccatgtgag agcgttttgg ggcttaggtg cgcttcagct actggatttg      300

tccgcaaatc aacttgaggc cctagcccca ggcacttttg ccccacttag ggccttgcgt      360

aatctgagtc tggctggcaa tcgtctagcg aggcttgaac ccgcagcatt gggtgcgcta      420

ccactattga gatcacttag cctacaggat aatgagcttg ccgcgctagc gccagggctg      480

ctggggagac ttcccgcgct tgacgctctg cacttgcgtg gcaacccgtg gggctgcggc      540

tgcgccttga ggcccctatg tgcgtggctg aggagacatc cgctaccagc atcagaagcc      600

gagactgttc tttgcgtttg gccgggtaga ctgactctat caccactaac ggccttttct      660

gacgcggctt tttcccactg cgctcaacct ttagcattaa gagac                      705


<210>  3952
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  3952
tgcccacagc cctgccggtg ccctgaccac gcaggggctg tggctgtctt ctgcagcttg       60

cggggccttc aggaggtccc cgaggacatc ccggccaaca ccgtgctcct gaagctcgat      120

gccaacaaga tctcccacct cccggacggg gccttccagc acctgcaccg gctcagggag      180

ctggatctgt ctcacaacgc catcgaggcc atcggctccg ccaccttcgc gggcctggcc      240

gggggcctgc ggctgctgga cctgtcttac aaccgcatcc agaggatccc caaggacgcc      300

ctgggcaaac tcagcgccaa gatacgcctg tcccacaacc ccctgcactg cgagtgcgcc      360

ctgcaggagg ccctgtggga gctgaagctg gaccccgact ctgtggacga gatcgcctgc      420

cacacctcag tgcaggagga gtttgtgggg aagcctctgg ttcaggctct ggatgcgggt      480

gccagcctct gcagcgtccc ccacaggacc acagac                                516


<210>  3953
<211>  1824
<212>  DNA
<213>  Homo Sapiens

<400>  3953
caccaagaca aagtgccctg taagatggtg gacaagaagg tctcgtgcca ggttctgggc       60

ctgctccagg tcccctcggt gctcccgcca gacactgaga cccttgatct atctgggaac      120

cagctgcgga gtatcctggc ctcacccctg ggcttctaca cggcacttcg tcacctggac      180

ctgagcacca atgagatcag cttcctccag ccaggagcct tccaggccct gacccacctg      240

gagcacctca gcctggctca caaccggctg gcgatggcca ctgcgctgag tgctggtggc      300

ctgggccccc tgccacgcgt gacctccctg gacctgtctg ggaacagcct gtacagcggc      360

ctgctggagc ggctgctggg ggaggcaccc agcctgcata ccctctcact ggcggagaac      420

agtctgactc gcctcacccg ccacaccttc cgggacatgc ctgcgctgga gcagcttgac      480

ctgcatagca acgtgctgat ggacatcgag gatggcgcct tcgagggtct gccccgcctg      540

acccatctca acctctccag gaattccctc acctgcatct ccgacttcag cctccagcag      600

ctgcgggtgc tagacctgag ctgcaacagc atcgaggcct ttcagacggc ctcccagccc      660

caggctgagt tccagctcac ctggcttgac ctgcgggaga acaaactgct ccatttcccc      720

gacctggccg cgctcccgag actcatctac ctgaacttgt ccaacaacct catccggctc      780

cccacagggc caccccagga cagcaagggc atccacgcac cttccgaggg ctggtcagcc      840

ctgcccctct cagcccccag cgggaatgcc agcggccgcc ccctttccca gctcttgaat      900

ctggatttga gctacaatga gattgagctc atccccgaca gctttcttga gcacctgacc      960

tccctgtgct tcctgaacct cagcagaaac tgcttgcgga cctttgaggc ccggcgctta     1020

ggctccctgc cctgcctgat gctccttgac ttaagccaca atgccctgga gacactggaa     1080

ctgggcgcca gagccctggg gtctctgcgg acgctgctcc tacagggcaa tgccctgcgg     1140

gacctgcccc catacacctt tgccaatctg gccagcctgc agcggctcaa cctgcagggg     1200

aaccgagtca gcccctgtgg ggggccagat gagcctggcc cctccggctg tgtggccttc     1260

tccggcatca cctccctccg cagcctgagc ctggtggata atgagataga gctgctcagg     1320

gcaggggcct tcctccacac cccactgact gagctggacc tttcttccaa tcctgggctg     1380

gaggtggcca cgggggcctt gggaggcctg gaggcctcct tggaggtcct ggcactgcag     1440

ggcaacgggc tgatggtcct gcaggtggac ctgccctgct tcatctgcct caagcggctc     1500

aatcttgccg agaaccgcct gagccacctt cccgcctgga cacaggctgt gtcactggag     1560

gtgctggacc tgcgaaacaa cagcttcagc ctcctgccag gcagtgccat gggtggcctg     1620

gagaccagcc tccggcgcct ctacctgcag gggaatccac tcagctgctg cggcaatggc     1680

tggctggcag cccagctgca ccagggccgt gtggacgtgg acgccaccca ggacctgatc     1740

tgccgcttca gctcccagga ggaggtgtcc ctgagccacg tgcgtcccga agactgtgag     1800

aaggggggac tgaagaacat caac                                            1824


<210>  3954
<211>  4641
<212>  DNA
<213>  Homo Sapiens

<400>  3954
gaggctcagc ctctggagtg ggtcaaggac ccgctccagc tcacctctaa tcccctgggg       60

ccgcctgact cctggtcttc ccactcctcc catttcccac gggaatctcc ccatgcgcct      120

actctcccag cagacccgtg ggactttgat cacctggggc cctctgcttc ctcagagatg      180

ccagccccac cccaggaatc gactgaaaat ttggttccat tcctggacac ctgggattca      240

gctggagagc agcccctgga gccagagcag ttcttggctt cacagcagga tttaaaggac      300

aagctgagtc cacaggaaag actccctgtt tcgcccaaga agctgaagaa agatccagct      360

cagcgttgga gccttgctga gattattgga attacacgcc aattatccac acctcagagt      420

cagaaacaga ctttgcagaa tgaatattcc agtacagata caccgtatcc cggtagcctg      480

cctccagaac tccgggtgaa gtcagatgag cctccagggc cctctgagca agttggacct      540

tctcaattcc atctagagcc cgaaactcaa aatccagaga cccttgaaga catccagtcc      600

tcttcactcc agcaagaagc cccagcacag cttccacagc tccttgagga agaaccttct      660

tcaatgcagc aggaggcccc agctctgcct ccagagtcct ctatggagag tctaactcta      720

ccgaatcatg aggtgtcagt tcaacctcca ggtgaggatc aagcttatta tcacttgccc      780

aacattacag ttaaacctgc agatgtggag gttaccataa cttcagagcc taccaatgag      840

acagaatctt cccaagccca gcaggagacc ccaattcagt ttccagagga ggtggaacct      900

tctgcaaccc aacaggaggc cccaattgag cctccagttt ctcctatgga gcatgaactt      960

tccatcagtg agcagcagca gccagttcag ccttctgagt cttctaggga ggtcgaatct     1020

tctctgaccc agcaggagac cccaggtcag cctccagaac atcatgaagt cacagtttca     1080

cctccaggtc accatcaaac tcatcattta gattcaccca gtgtctctgt gaagcctcca     1140

gacgtgcagc tcaccatagc agcagagcct agtgcagagg tgggaacttc tctagtccac     1200

caggaggcta cagctcggct ctcagggtca ggtaatgatg tagaacctcc cgccatccag     1260

cacgggggcc cacctctgct tccagagtca tcagaagaag ctggaccttt agcagttcaa     1320

caggagactt catttcaatc tccggaacct attaataatg agaacccctc tccaacccag     1380

caggaggctg cagctgagca tccacagacc gctgaggagg gtgagtcttc cctaacccat     1440

caggaggccc cagctcagac tccagagttc cctaatgtag ttgtagctca acctccagag     1500

cattcacacc tgactcaagc cacagttcaa cctttggatc tggggtttac catcactcca     1560

gaatccatga cagaggttga actttctcca accatgaagg agaccccaac tcagcctcct     1620

aagaaagttg taccccaact tcgagtatat caaggggtaa caaatccaac accaggtcag     1680

gatcaagctc agcatccagt gtcacccagc gttacagttc aacttttgga cctgggactt     1740

accatcactc cagaacccac tacggaggtt ggacattcta cagccccgaa gaggactata     1800

gtttctccaa agcatcctga ggtgacactt cctcatccag accaggttca gactcagcat     1860

tcacacctga ctcgagccac agttcaacct ttggacctgg ggtttaccat cactccaaaa     1920

tccatgacag aggttgaacc ttctacagcc ctgatgacta cagctcctcc tccaggacac     1980

cctgaggtga cacttccacc ttcagacaag ggtcaggctc agcattcaca cctgactcaa     2040

gccaccgttc aacctctgga cctggagctt accataacta caaaacctac tacagaggtt     2100

aaaccatctc caaccacaga ggagacctca actcagcctc cagacctggg acttgccatc     2160

attccagaac ccactacaga gactggacat tctacagccc tggagaagac tacagctcct     2220

catccagacc gggttcagac tctgcatcaa agcctgactg aagtcacagg tccacctact     2280

gaactagaac ctgctcagga ttcactggtg cagtctgaaa gttacaccca aaataaggct     2340

ttaactgcac cagaggaaca caaggcctcc acaagcacca acatatgtga gctctgtacc     2400

tgcggagatg agatgttgtc atgtattgat ctcaacccag agcagaggct ccgccaagtg     2460

cctgtgccag agcccaacac ccacaatggc accttcacca tcttaaattt ccaaggaaac     2520

tatatttctt acattgatgg aaatgtatgg aaagcataca gttggactga gaaactaatt     2580

ctcagagaaa ataacttgac tgaattacac aaggattcat ttgaaggcct gctatccctc     2640

cagtatttag atttatcctg caataaaata cagtctattg aaagacatac atttgaacca     2700

ctaccatttt tgaagtttat aaatcttagt tgcaatgtaa ttacagaact cagctttgga     2760

acatttcagg cctggcacgg aatgcagttt ttacataagt taattctcaa tcacaatcct     2820

ctgacaactg ttgaagatcc gtatctcttt aaattgccag cattaaaata tctagacatg     2880

ggaacaacgc tagtcccact tacaacactt aagaacattc tcatgatgac tgttgaactg     2940

gaaaaactga tcttacctag ccatatggcc tgctgcctct gccaatttaa aaacagcatt     3000

gaggctgtct gcaagacagt caagctgcat tgcaacagtg catgtctgac aaacaccaca     3060

cattgtcctg aagaagcatc ggtagggaat ccagaaggag cgttcatgaa ggtgttacaa     3120

gcccggaaga actacacaag cactgagctg attgttgagc cagaggagcc ctcagacagc     3180

agtggcatca acttgtcagg ctttgggagt gagcagctag acaccaatga cgagagtgat     3240

tttatcagta cactaagtta catcttgcct tatttctcag cggtaaacct agatgtgaaa     3300

tcactgttac taccgttcat taaactgcca accacaggaa acagcctggc aaagattcaa     3360

actgtaggcc aaaaccggca gagagtgaag agagtcctca tgggcccaag gagcatccag     3420

aaaaggcact tcaaagaggt aggaaggcag agcatcagga gggaacaggg tgcccaggca     3480

tctgtggaga acgctgccga agaaaaaagg ctcacgagtc cagccccaag ggaggtggaa     3540

cagccccaca cacagcaggg gcctgagaag ttagcgggaa acgccgtcta caccaagcct     3600

tcgttcaccc aagagcataa ggcagcagtc tctgtgctga aacccttctc caagggcgcg     3660

ccttctacct ccagccctgc aaaagcccta ccacaggtga gagacagatc gaaagactta     3720

acccacgcta tttccatttt agaaagtgca aaggctagag ttacaaatac gaagacgtct     3780

aaaccaatcg tacatgccag aaaaaaatac cgctttcaca aaactcgctc ccacgtgacc     3840

cacagaacaa ccaaagtcaa aaagagtcca aaggtcagaa agaaaagtta tctgagtaga     3900

ctgatgctcg caaacaggct tccattctct gcagcgaaga gcctcataaa ttccccttca     3960

caaggggctt tttcatcctt aggagacctg agtcctcaag aaaacccttt tctggaagta     4020

tctgctcttt cagaacattt tatagggaag aataatacaa aacacacaac tgcaagaaat     4080

gcctttgaag aaaatgattt tatggaaaac actaacatgc cagaaggaac catctctgaa     4140

aacacaaact acaatcatcc tcctgaggca gattccgctg ggactgcatt caacttaggg     4200

ccaactgtta aacaaactga gacaaaatgg gaatacaaca acgtgggcac tgacctgtcc     4260

cccgagccca aaagcttcaa ttacccattg ctctcgtccc caggtgatca gtttgaaatt     4320

cagctaaccc agcagctaca gtcccttatc cccaacaaca atgtgagaag gctcattgct     4380

catgttatcc ggaccttgaa gatggactgc tctggggccc atgtgcaagt gacctgtgcc     4440

aagctcatct ccaggacagg ccacctgatg aagcttctca gtgggcagca ggaagtaaag     4500

gcatccaaga tagaatggga tacggaccaa tggaagattg agaactacat taatgagagc     4560

acagaagccc agagtgaaca gaaagagaag tcgcttgagc tcaaaaaaga agttccagga     4620

tatggctata ctgacaaact c                                               4641


<210>  3955
<211>  4638
<212>  DNA
<213>  Homo Sapiens

<400>  3955
gaggctcagc ctctggagtg ggtcaaggac ccgctccagc tgacccctaa ccccctgggg       60

ccgcctgagc cctggtcttc ccactcctcc catttcccac gggaatctcc ccatgcgcct      120

actctcccag cagacccgtg ggactttgat cacctggggc cctctgcttc ctcagagatg      180

ccagccccac cccaggaatc gactgaaaat ttggttccat tcctggacac ctgggattca      240

gctggagagc tgcccctgga gccagagcag ttcttggctt cacagcagga tttaaaggac      300

aagctgagtc cacaggaaag gctccctgtt tcgcccaaga agctgaagaa agatccagct      360

cagcgttgga gccttgctga gattattgga attatacacc aattatccac acctcagagt      420

cagaaacaga ctttgcagaa tgaatattcc agtacagata caccgtatcc cggtagcctg      480

cctccagaac tccgggtgaa gtcagatgag cctccagggc cctctgagca agttggacct      540

tctcaattcc atctagagcc cgaaactcaa aatccagaga cccttgaaga catccagtcc      600

tcttcactcc agcaagaagc cccagcacag cttccacagc tccttgagga agaaccttct      660

tcaatgcagc aggaggcccc agctctgcct ccagagtcct ctatggagag tctaactcta      720

ccgaatcatg aggtgtcagt tcaacctcca ggtgaggatc aagcttatta tcacttgccc      780

aacattacag ttaaacctgc agatgtggag gttaccataa cttcagagcc taccaatgag      840

acagaatctt cccaagccca gcaggagacc ccaattcagt ttccagagga ggtggaacct      900

tctgcaaccc aacaggaggc cccaattgag cctccagttc ctcctatgga gcatgaactt      960

tccatcagtg agcagcagca gccagttcag ccttctgagt cttctaggga ggtcgaatct     1020

tctccgaccc agcaggagac cccaggtcag cctccagaac atcatgaagt cacagtttca     1080

cctccaggtc accatcaaac tcatcattta gcttcaccca gtgtctctgt gaagcctcca     1140

gacgtgcagc tcaccatagc agcagagcct agtgcagagg tgggaacttc tctagtccac     1200

caggaggcta caactcggct ctcagggtca ggtaatgatg tagaacctcc cgccatccag     1260

cacgggggcc cacctctgct tccagagtca tcagaagaag ctggaccttt agcagttcaa     1320

caggagactt catttcaatc tccggaacct attaataatg agaacccctc tccaacccag     1380

caggaggctg cagctgagca tccacagacc gctgaggagg gtgagtcttc cctaacccat     1440

caggaggccc cagctcagac tccagagttc cctaatgtag ttgtagctca acctccagag     1500

cattcacacc tgactcaagc cacagttcaa cctttggatc tggggtttac catcactcca     1560

gaatccatga cagaggttga actttctcca accatgaagg agaccccaac tcagcctcct     1620

aagaaagttg taccccaact tcgagtatat caaggggtaa caaatccaac accaggtcag     1680

gatcaagctc agcatccagt gtcacccagc gttacagttc aacttttgga cctgggactt     1740

accatcactc cagaacccac tacggaggtt ggacattcta cacccccgaa gaggactata     1800

gtttctccaa agcatcctga ggtgacactt ccacatccag accaggttca gactcagcat     1860

tcacacctga ctcgagccac agttcaacct ttggacctgg ggtttaccat cactccaaaa     1920

tccatgacag aggttgaacc ttctacagcc ctgatgacta cagctcctcc tccaggacac     1980

cctgaggtga cacttccacc ttcagacaag ggtcaggctc agcattcaca cctgactcaa     2040

gccaccgttc aacctctgga cctggagctt accataacta caaaacctac tacagaggtt     2100

aaaccatctc caaccacgga ggagacctca actcagcttc cagacctggg acttgccatc     2160

attccagaac ccactacaga gactggacat tctacagccc tggagaagac tacagctcct     2220

cgtccagacc gggttcagac tctgcatcga agcctgactg aagtcacagg tccacctact     2280

gaactagaac ctgctcagga ttcactggtt cagtctgaaa gttacaccca aaataaggct     2340

ttaactgcac cagaggaaca caaggcctcc acaagcacca acatatgtga gctctgtacc     2400

tgcggagatg agatgttgtc atgtattgat ctcaacccag agcagaggct ccgccaagtg     2460

cctgtgccag agcccaacac ccacaatggc accttcacca tcttaaattt ccaaggaaac     2520

tatatttctt acattgatgg aaatgtatgg aaagcataca gttggaccga gaaactaatt     2580

ctcagagaaa ataacttgac tgaattacac aaggattcat ttgaaggcct gctatccctc     2640

cagtatttag atttatcctg caataaaata cagtctattg aaagacatac atttgaacca     2700

ctaccatttt tgaagtttat aaatcttagt tgcaatgtaa ttacagaact cagctttgga     2760

acatttcagg cctggcacgg aatgcagttt ttacataagt taattctcaa tcacaatcct     2820

ctgacaactg ttgaagatcc atatctcttt aaattgccag cattaaaata tctagacatg     2880

ggaacaacgc tagtcccact tacaacactt aagaacattc tcatgatgac tgttgaactg     2940

gaaaaactga tcgtacctag ccatatggcc tgctgcctct gccaatttaa aaacagcatt     3000

gaggctgtct gcaagacagt caagctgcat tgcaacagtg catgtctgac aaacaccaca     3060

cattgtcctg aagaagcatc tgtagggaat ccagaaggag cgttcatgaa ggtgttacaa     3120

gcccggaaga attacacaag cactgagctg actattgagc cggaggagcc ctcagacagc     3180

agtggcatca acttgtcagg ctttgggagt gagcagctag acaccaatga cgagagtgat     3240

gttaccagta cactaagtta catcttacct tatttctcag ccgttaacct agatgtgaaa     3300

tcactgttac taccgttcat taaactgcca accacaggaa acagcctggc aaagattcaa     3360

actgtaggca aaaaccggca gagactgaat agagtcctca tgggcccaag gagcatccag     3420

aaaaggcact tcaaagaggt aggaaggcag agcatcagga gggaacaggg tgcccaggca     3480

tctgtggaga acactgccga agaaaaaagg ctcggaagtc cagccccaag ggagctgaaa     3540

cagcctcaca cacagcaggg gcctgagaag ttagcgggaa acgccgtcta caccaagcct     3600

tcgttcaccc aagagcataa ggcagcagtc tctgtgctga aacccttctc caagggcgcg     3660

ccttctacct ccagccctgc aaaagcccta ccacaggtga gagacagatg gaaagactta     3720

acccacgcta tttccatttt agaaagtgca aaggctagag ttacaaatat gaagacatct     3780

aaacccatcg tacattccag aaaaaaatac cgctttcaca aaactcgctc ccgcatgacc     3840

cacagaacac ccaaggtcaa aaagagtcca aaggtcagaa agaaaagtta tctgagtaga     3900

ctgatgctct caaacaggct tccgttctct gcagcgaaga gcctcataaa ttccccttca     3960

caaggggctt tttcatcctt aagagacctg agtcctcaag aaaatccttt tctggaagta     4020

tctgctcctt cagaacattt tatagaaaac aataatacaa aagacacaac tgcaagaaat     4080

gcctttgaag aaaatgtttt tatggaaaac actaacatgc cagaaggaac catctctgaa     4140

aacgcaaact acaatcatcc tcctgaggca gattccgctg ggactgcatt caacttaggg     4200

ccaactgtta aacaaactga gacaaaatgg gaatacaaca acgtgggcac tgacctgtcc     4260

cccgagccca aaagcttcaa ttacccattg ctctcgtccc caggtgatca gtttgaaatt     4320

cagctaaccc agcagctgca gtccgttatc cccaacaaca atgtgagaag gctcattgct     4380

catgttatcc ggaccttgaa gatggactgc tctggggccc atgtgcaagt gacctgtgcc     4440

aagctcgtct ccaggacagg ccacctgatg aagcttctca gtgggcagca ggaagtaaag     4500

gcatccaaga tagaatggga tacggaccaa tggaagactg agaactacat taatgagagc     4560

acagaagccc agagtgaaca gaaagagaag tcgcttgagt tcacaaaaga acttccagga     4620

tatggctata ccaaaaaa                                                   4638


<210>  3956
<211>  2481
<212>  DNA
<213>  Homo Sapiens

<400>  3956
ctggtgtggg tcaaggaccc gctccagctg acctctaacc ccctggggcc acctgagccc       60

tggtcttccc gctcctccca tctcccatgg gaatctcccc atgcacctgc tcccccagca      120

gccccggggg actttgatta cctggggccc tctgcttctt cgcagatgtc agccctgcct      180

caggaaccaa ctgaaaattt ggctccattc ctgaaggaat tggattcagc tggagagctg      240

cccctggggc cagagccgtt cttggctgca catcaggact taaatgacaa gcggactcca      300

gaagaaaggc tcccagaggt ggttccgctt ctcaaccggg atcagaacca ggccctagtt      360

cagcttcctc gcctcaagtg ggttcaaact acagatctag atcgggctgc aggtcatcag      420

gcagatgaaa tacttgttcc actagacagt aaggtttcaa gaccaaccaa atttgttgtt      480

tcgcccaaga acctgaagaa agatctagct gaacgttgga gccttcctga gattgttggg      540

attccacacc aattatccaa acctcagcgt cagaaacaga ctttgccaga tgattatttg      600

agtatggaca cactgtatcc cggcagccta cctccagaac tccgggtgaa cgcagatgag      660

cctccagggc ctcctgagca agttggactt tctcaattcc atctagagcc caaaagtcaa      720

aatccagaga cccttgaaga catccagtcc tcttcactcc aggaagaagc cccagcgcag      780

cttctacagc tccctcagga ggtagaacct tcaacccagc aggaggcccc agctctgcct      840

ccagagtcct ctatggagag tctagctcaa actccactga atcatgaagt gacagttcaa      900

cctccaggtg aggatcaagc tcattataat ttgcccaagt ttacagtcaa acctgcagat      960

gtggaggtta ccatgacttc agagcctaaa aatgagacag aatctaccca agcccagcag     1020

gaggccccaa ttcagcctcc cgaggaggcg gaaccttctt ctacagccct gaggactaca     1080

gatcctcctc cagaacaccc tgaggtgaca cttccacctt cagacaaggg tcaggctcag     1140

cattcacacc tgactgaagc cacagttcaa cctctggacc tggagcttag cataactaca     1200

gagcctacta cagaggttaa accgtctcca accacggagg aaacctcagc tcagcctcca     1260

gacccggggc ttgccataac tccagaaccc actacagaga ttggacattc cacagccctg     1320

gagaagacta gagctcctca tccagaccag gttcagactc tgcatcgaag cctgactgaa     1380

gtcacaggtc cacctacaaa gttagaatct tcgcaggatt cattggtgca gtctgaaact     1440

gcaccagagg aacagaaggc ctccacaagc accaacatat gtgagctctg cacctgcgga     1500

gatgagactc tgtcatgtgt tggtctcagc ccaaagcaga ggctccgcca agtgcctgtg     1560

ccagagcccg acacctacaa tggcatcttc accaccttaa atttccaagg aaactatatt     1620

tcataccttg atggaaatgt atggaaagca tacagttgga ccgagaaact aattctcagt     1680

gaaaattatt tgactgaatt acctaaggat tcatttgaag gcctgctata cctccagtat     1740

ttaattctca atcgcaatcc tctgactact gtcgaagatc catatctctt tgaactgccg     1800

gcattaaaat atctagacat gggaacaaca cacatcacac ttacaacact taagaacatt     1860

ctcacgatga ctgttgaact ggaaaaactg atcttaccta gccatatggc ctgctgcctc     1920

tgccaattta aaaatagcat tgaggctgtc tgcaagacag tcaagctgca ttgcaacact     1980

gcatgtctga ctaacagcat acattgtcct gaagaagcat ctgtagggaa tccagaagga     2040

gcgttcatga agatgttaca agcccggaag cagcacatga gcactcagct gactattgag     2100

tcggaggcgc cctcagacag cagtggcatc aacttgtcag gctttggggg tgatcagctt     2160

gaaattcagc taaccgagca gctacggtcc ctcatcccca acgaggatgt gagaaagttc     2220

atgtctcatg ttatccggac cttgaaaatg gaatgttcag aaacacatgt gcaagggagc     2280

tgtgccaagc tcatgttgcg aacaggcctc ctgatgaagc ttctcagcga gcagcaggaa     2340

gcaaaggcat tgaatgtaga atgggatacg gaccaacaaa aaacaaatta tattaatgag     2400

aacatggaac agaatgaaca gaaagagcag aagtcaagtg agctcatgaa agaagttcca     2460

ggagatgact ataagaacaa a                                               2481


<210>  3957
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  3957
tgtccagcag gctgcgcctg taccgatccc cacacggttg actgtcgtga taggggactg       60

ccatcagttc cagatccgtt ccctcttgat gtaaggaagc tgttggtcgc cggtaatcgt      120

atccagagga ttccggaaga tttttttatt ttctacggcg acttagttta cttagatttc      180

cgtaacaaca gcttgagatc tttagaggag ggaacattct caggttccgc gaagttagtg      240

ttccttgatc taagttacaa taacctaact caattagggg caggtgcgtt caggtctgcc      300

ggacgtttag tcaagttatc attagccaac aataatctgg tcggggttca cgaagatgca      360

tttgaaacgc ttgaaagcct acaagtttta gagttaaacg acaacaatct acgttcccta      420

tccgtggctg cccttgcagc actacccgcg ttgagatccc ttaggttgga tggcaatccg      480

tggttgtgcg attgtgattt tgcacacctg ttctcttgga tccaggaaaa tgctagcaag      540

ctaccaaagg gattggacga gattcagtgc agcctgccta tggagtcccg tcgtataagt      600

ctgagagagc tttcagaagc tagtttctcc gagtgcaggt tttcactttc ccttactgac      660

ttatgt                                                                 666


<210>  3958
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  3958
tgtcccaagg gctgtctttg ttcttcctct gggggtttaa atgtcacctg tagcaatgca       60

aatctcaagg aaatacctag agatcttcct cctgaaacag tcttactgta tctggactcc      120

aatcagatca catctattcc caatgaaatt tttaaggacc tccatcaact gagagttctc      180

aacctgtcca aaaatggcat tgagtttatc gatgagcatg ccttcaaagg agtagctgaa      240

accttgcaga ctctggactt gtccgacaat cggattcaaa gtgtgcacaa aaatgccttc      300

aataacctga aggccagggc cagaattgcc aacaacccct ggcactgcga ctgtactcta      360

cagcaagttc tgaggagcat ggcgtccaat catgagacag cccacaacgt gatctgtaaa      420

acgtccgtgt tggatgaaca tgctggcaga ccattcctca atgctgccaa cgacgctgac      480

ctttgtaacc tccctaaaaa aactaccgat tat                                   513


<210>  3959
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3959
gtgccctcac cgcaagtgcc gcccagaggg tgctacgtgg caaaggaggc aggggaacgt       60

acttttcgtt gcagccaggc gggcctttcc gcagtgcctt ctgggatacc gaacgacacc      120

aggaagctat accttgacgc taatcagtta gccagtgttc ccgcaggagc cttccagcat      180

ttgccagtgc tggaagagtt agacctttcc cataatgctc tggcacatct gtcaggtgct      240

gcgtttcaag gacttgaggg cacccttaga cacctagatc tatccgcaaa ccagttagcg      300

tccgtcccgg ttgaagcatt cgttggtttg cagatacaag taaatctatc tgcaaatccc      360

tggcactgtg attgcgcctt acaagaagtt ctaagacaag ttaggttagt accgggtacc      420

ggaaccggaa tcgtgtgtgg gtcaggtgcg agacctgatc ttgtgggcca agaatttctt      480

ctgttggcgg gtgaagaaga attatgtggt agcggttggg gcggagccag gagaagtaca      540

gacgtggca                                                              549


<210>  3960
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  3960
gcctcagccg ggccccagaa ctgcccctcc gtctgctcgt gcagtaacca gttcagcaag       60

gtggtgtgca cgcgccgggg cctctccgag gtcccgcagg gtattccctc gaacacccgg      120

tacctcaacc tcatggagaa caacatccag atgatccagg ccgacacctt ccgccacctc      180

caccacctgg aggtcctgca gttgggcagg aactccatcc ggcagattga ggtgggggcc      240

ttcaacggcc tggccagcct caacaccctg gagctgttcg acaactggct gacagtcatc      300

cctagcgggg cctttgaata cctgtccaag ctgcgggagc tctggcttcg caacaacccc      360

atcgaaagca tcccctctta cgccttcaac cgggtgccct ccctcatgcg cctggacttg      420

ggggagctca agaagctgga gtatatctct gagggagctt ttgaggggct gttcaacctc      480

aagtatctga acttgggcat gtgcaacatt aaagacatgc ccaatctcac ccccctggtg      540

gggctggagg agctggagat gtcagggaac cacttccctg agatcaggcc tggctccttc      600

catggcctga gctccctcaa gaagctctgg gtcatgaact cacaggtcag cctgattgag      660

cggaatgctt ttgacgggct ggcttcactt gtggaactca acttggccca caataacctc      720

tcttctttgc cccatgacct ctttaccccg ctgaggtacc tggtggagtt gcatctacac      780

cacaaccctt ggaactgtga ttgtgacatt ctgtggctag cctggtggct tcgagagtat      840

atacccacca attccacctg ctgtggccgc tgtcatgctc ccatgcacat gcgaggccgc      900

tacctcgtgg aggtggacca ggcctccttc cagtgctctg cccccttcat catggacgca      960

cctcgagacc tcaacatttc tgagggtcgg atggcagaac ttaagtgtcg gactccccct     1020

atgtcctccg tgaagtggtt gctgcccaat gggacagtgc tcagccacgc ctcccgccac     1080

ccaaggatct ctgtcctcaa cgacggcacc ttgaactttt cccacgtgct gctttcagac     1140

actggggtgt acacatgcat ggtgaccaat gttgcaggca actccaacgc ctcggcctac     1200

ctcaatgtga gcacggctga gcttaacacc tccaactaca gcttcttcac cacagtaaca     1260

gtggagacca cggagatctc gcctgaggac acaacgcgaa agtacaagcc tgttcctacc     1320

acgtccactg gttaccagcc ggcatatacc acctctacca cggtgctcat tcagactacc     1380

cgtgtgccca agcaggtggc agtacccgcg acagacacca ctgacaagat gcagaccagc     1440

ctggatgaag tcatgaagac caccaag                                         1467


<210>  3961
<211>  1623
<212>  DNA
<213>  Homo Sapiens

<400>  3961
gccggtggag gtggagtggc cgtgacgtct gccgccggag ggggctcccc gccggccacc       60

tcctgccccg tggcctgctc ctgcagcaac caggccagcc gggtgatctg cacacggaga      120

gacctggccg aggtcccagc cagcatcccg gtcaacacgc ggtacctgaa cctgcaagag      180

aacggcatcc aggtgatccg gacggacacg ttcaagcacc tgcggcacct ggagattctg      240

cagctgagca agaacctggt gcgcaagatc gaggtgggcg ccttcaacgg gctgcccagc      300

ctcaacacgc tggagctttt tgacaaccgg ctgaccacgg tgcccacgca ggccttcgag      360

tacctgtcca agctgcggga gctctggctg cggaacaacc ccatcgagag catcccctcc      420

tacgccttca accgcgtgcc ctcgctgcgg cgcctggacc tgggcgagct caagcggctg      480

gaatacatct cggaggcggc cttcgagggg ctggtcaacc tgcgctacct caacctgggc      540

atgtgcaacc tcaaggacat ccccaacctg acggccctgg tgcgcctgga ggagctggag      600

ctgtcgggca accggctgga cctgatccgc ccgggctcct tccagggtct caccagcctg      660

cgcaagctgt ggctcatgca cgcccaggta gccaccatcg agcgcaacgc cttcgacgac      720

ctcaagtcgc tggaggagct caacctgtcc cacaacaacc tgatgtcgct gccccacgac      780

ctcttcacgc ccctgcaccg cctcgagcgc gtgcacctca accacaaccc ctggcattgc      840

aactgcgacg tgctctggct gagctggtgg ctcaaggaga cggtgcccag caacacgacg      900

tgctgcgccc gctgtcatgc gcccgccggc ctcaaggggc gctacattgg ggagctggac      960

cagtcgcatt tcacctgcta tgcgcccgtc atcgtggagc cgcccacgga cctcaacgtc     1020

accgagggca tggctgccga gctcaaatgc cgcacgggca cctccatgac ctccgtcaac     1080

tggctgacgc ccaacggcac cctcatgacc cacggctcct accgcgtgcg catctccgtc     1140

ctgcatgacg gcacgcttaa cttcaccaac gtcaccgtgc aggacacggg ccagtacacg     1200

tgcatggtga cgaactcagc cggcaacacc accgcctcgg ccacgctcaa cgtctcggcc     1260

gtggaccccg tggcggccgg gggcaccggc agcggcgggg gcggccctgg gggcagtggt     1320

ggtgttggag ggggcagtgg cggctacacc tacttcacca cggtgaccgt ggagaccctg     1380

gagacgcagc ccggagagga ggccctgcag ccgcggggga cggagaagga accgccaggg     1440

cccacgacag acggtgtctg gggtgggggc cggcctgggg acgcggccgg ccctgcctcg     1500

tcttctacca cggcacccgc cccgcgctcc tcgcggccca cggagaaggc gttcacggtg     1560

cccatcacgg atgtgacgga gaacgccctc aaggacctgg acgacgtcat gaagaccacc     1620

aaa                                                                   1623


<210>  3962
<211>  1449
<212>  DNA
<213>  Homo Sapiens

<400>  3962
cagacctgcc cttctgtgtg ctcctgcagc aaccagttca gcaaggtgat ttgtgttcgg       60

aaaaacctgc gtgaggttcc ggatggcatc tccaccaaca cacggctgct gaacctccat      120

gagaaccaaa tccagatcat caaagtgaac agcttcaagc acttgagaca cttggaaatc      180

ctacagttga gtaggaacca tatcagaacc attgaaattg gggctttcaa tggtctggcg      240

aacctcaaca ctctggaact ctttgacaat cgtcttacta ccatcccgaa tggagctttt      300

gtatacttgt ctaaactgaa ggagctctgg ttgcgaaaca accccattga aagcatccct      360

tcttatgctt ttaacagaat tccttctttg cgccgactag acttagggga attgaaaaga      420

ctttcataca tctcagaagg tgcctttgaa ggtctgtcca acttgaggta tttgaacctt      480

gccatgtgca accttcggga aatccctaac ctcacaccgc tcataaaact agatgagctg      540

gatctttctg ggaatcattt atctgccatc aggcctggct ctttccaggg tttgatgcac      600

cttcaaaaac tgtggatgat acagtcccag attcaagtga ttgaacggaa tgcctttgac      660

aaccttcagt cactagtgga gatcaacctg gcacacaata atctaacatt actgcctcat      720

gacctcttca ctcccttgca tcatctagag cggatacatt tacatcacaa cccttggaac      780

tgtaactgtg acatactgtg gctcagctgg tggataaaag acatggcccc gtcgaacaca      840

gcttgttgtg cccggtgtaa cactcctccc aatctaaagg ggaggtacat tggagagctc      900

gaccagaatt acttcacatg ctatgctccg gtgattgtgg agccccctgc agacctcaat      960

gtcactgaag gcatggcagc tgagctgaaa tgtcgggcct ccacatccct gacatctgta     1020

tcttggatta ctccaaatgg aacagtcatg acacatgggg cgtacaaagt gcggatagct     1080

gtgctcagtg atggtacgtt aaatttcaca aatgtaactg tgcaagatac aggcatgtac     1140

acatgtatgg tgagtaattc cgttgggaat actactgctt cagccaccct gaatgttact     1200

gcagcaacca ctactccttt ctcttacttt tcaaccgtca cagtagagac tatggaaccg     1260

tctcaggatg aggcacggac cacagataac aatgtgggtc ccactccagt ggtcgactgg     1320

gagaccacca atgtgaccac ctctctcaca ccacagagca caaggtcgac agagaaaacc     1380

ttcaccatcc cagtgactga tataaacagt gggatcccag gaattgatga ggtcatgaag     1440

actaccaaa                                                             1449


<210>  3963
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  3963
tcaaagtgtc caaataattg tctgtgtcaa gcccaagaag taatctgcac agggaagcag       60

ttaaccgaat acccccttga catacccctg aacacccgga ggctgttcct gaacgagaac      120

agaatcacta gtttgccagc aatgcatcta ggactcctca gtgaccttgt ttatttggac      180

tgtcagaaca accggattcg agaggtgatg gattatacct tcatcggggt cttcaaactc      240

atctaccttg acctcagctc caacaaccta acctcgatct ccccattcac tttctcggtg      300

ctcagcaacc tggtgcagct gaacattgcc aacaaccctc acctgttatc gcttcacaag      360

ttcacctttg ccaacaccac ctctttgagg tacctggacc tcagaaatac cggcttgcag      420

accctggaca gtgctgcctt ataccacctc actactctgg agaccctgtt tctgagtgga      480

aacccctgga agtgcaactg ctctttcctg gacttcgcca tcttcttaat agtgttccat      540

atggacccct cagatgatct aaatgccaca tgtgtggagc ccacagagct gacagggtgg      600

cccatcaccc gggtggggaa cccactccga tacatgtgca tcacgcacct ggaccacaaa      660

gac                                                                    663


<210>  3964
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  3964
ggcaccagct gccccgtcct ttgcacatgc cgtaaccagg tggtggattg tagcagccag       60

cggctattct ccgtgccccc agacctgcca atggacaccc gaaacctcag cctggcccac      120

aaccgcatca cagcagtgcc gcctggctac ctcacatgct acatggagct ccaggtgctg      180

gatttgcaca acaactcctt aatggagctg ccccggggcc tcttcctcca tgccaagcgc      240

ttggcacact tggacctgag ctacaacaat ttcagccatg tgccagccga catgttccag      300

gaggcccatg ggctagtcca catcgacctg agccacaacc cctggctgcg gagggtgcat      360

ccccaggcct ttcagggcct catgcagctc cgagacctgg acctcagtta tgggggcctg      420

gccttcctca gcctggaggc tcttgagggc ctaccggggc tggtgaccct gcagatcggt      480

ggcaatccct gggtgtgtgg ctgcaccatg gaacccctgc tgaagtggct gcgaaaccgg      540

atccagcgct gtacagcaga ttctcagctg gctgagtgcc ggggccctcc tgaagtcgag      600

ggcgccccgc tcttctcact cactgaggag agcttcaagg cctgccacct gaccctgacc      660

ctggatgatt ac                                                          672


<210>  3965
<211>  1326
<212>  DNA
<213>  Homo Sapiens

<400>  3965
tctcttgtag cattgtattt ggataattct aacattctgt atgtatatcc aaaagccttt       60

gttcaattga ggcatctata ttttctattt ctaaataata atttcatcaa acgcttagat      120

cctggaatat ttaagggact tttaaatctt cgtaatttat atttacagta taatcaggta      180

tcttttgttc cgagaggagt atttaatgat ctagtttcag ttcagtactt aaatctacaa      240

aggaatcgcc tcactgtcct tgggagtggt acctttgttg gtatggttgc tcttcggata      300

cttgatttat caaacaataa cattttgagg atatcagaat caggctttca acatcttgaa      360

aaccttgctt gtttgtattt aggaagtaat aatttaacaa aagtaccatc aaatgccttt      420

gaagtactta aaagtcttag aagactttct ttgtctcata atcctattga agcaatacag      480

ccctttgcat ttaaaggact tgccaatctg gaatacctcc tcctgaaaaa ttcaagaatt      540

aggaatgtta ctagggatgg gtttagtgga attaataatc ttaaacattt gatcttaagt      600

cataatgatt tagagaattt aaattctgac acattcagtt tgttaaagaa tttaatttac      660

cttaagttag atagaaacag aataattagc attgataatg atacatttga aaatatggga      720

gcatctttga agatccttaa tctgtcattt aataatctta cagccttgca tccaagggtc      780

cttaagccgt tgtcttcatt gattcatctt caggcaaatt ctaatccttg ggaatgtaac      840

tgcaaacttt tgggccttcg agactggcta gcatcttcag ccattactct aaacatctat      900

tgtcagaatc ccccatccat gcgtggcaga gcattacgtt atattaacat tacaaattgt      960

gttacatctt caataaatgt atccagagct tgggctgttg taaaatctcc tcatattcat     1020

cacaagacta ctgcgctaat gatggcctgg cataaagtaa ccacaaatgg cagtcctctg     1080

gaaaatactg agactgagaa cattactttc tgggaacgaa ttcctacttc acctgctggt     1140

agattttttc aagagaatgc ctttggtaat ccattagaga ctacagcagt gttacctgtg     1200

caaatacaac ttactacttc tgttaccttg aacttggaaa aaaacagtgc tctaccgaat     1260

gatgctgctt caatgtcagg gaaaacatct ctaatttgta cacaagaagt tgagaagttg     1320

aatgag                                                                1326


<210>  3966
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  3966
caggtcaccc aagacaagat gatctgcctg ccttgtaagt gggtcaccaa ggactcctgc       60

aatgattcgt tccggggctg ggcagcccct ggcccggagc ccacctaccc caactccacc      120

attctgccga cccctgacac gggccccaca ggcatcaagt atgacctgga ccggcaccag      180

tacaactacg tggacgctgt gtgctatgag aaccgactgc actggtttgc caag            234


<210>  3967
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  3967
ctgacgcaga gcagggttct gtgctgtctt ccatgcaaag tggaatttga caatcactgt       60

gccgtgcctt gggacatcct gaaagccagc atgaacacat cctctaatcc tgggacaccg      120

cttccgctcc ccctccgaat tcagaatgac ctccaccgac agcagtactc ctatattgat      180

gccgtctgtt acgagaaaca gctccattgg tttgcaaag                             219


<210>  3968
<211>  246
<212>  DNA
<213>  Homo Sapiens

<400>  3968
acacttcagg ttatgcagga taaaatcata tgtctaccga agcgtgtcca accagctcaa       60

aatcattcct cattgagcaa tgtaagccaa gccgtcgcct ccaccacccc gctgcccccc      120

ccaaagcctt cacctgctaa tccgattacg gtcgaaatga aaggcttgaa aacagacttg      180

gacctgcaac aatacagttt cataaatcaa atgtgttacg aaagagccct tcattggtac      240

gcgaaa                                                                 246


<210>  3969
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  3969
accatgcaac ttaccaaaga tcaggtggtc tgtttgccag tattgccatc tcctgtaaat       60

tcaaaggcac atacaccacc aggaaatgcc gaggtcacca ccaacatccc aaagatggaa      120

gcagccacca accaagacca agatgggcgg acaacaaacg acatttcctt tgggacatct      180

gctgtgacac ctgacatacc tctcagagcc acatatcctc gcacagattt cgcacttcca      240

aatcaggagg caaagaaaga gaagaaagat ccaacaggtc gaaaaacaaa cttggatttt      300

cagcaatatg tatttattaa tcaaatgtgt taccatctgg cccttccgtg gtattctaag      360


<210>  3970
<211>  1818
<212>  DNA
<213>  Homo Sapiens

<400>  3970
tccatacaga atagtgagtg tccacaactt tgcgtatgtg aaattcgtcc ctggtttacc       60

ccacagtcaa cttacagaga agccaccact gttgattgca atgacctccg cttaacaagg      120

attcccagta acctctctag tgacacacaa gtgcttctct tacagagcaa taacatcgcg      180

aagactgtgg atgagctgca gcagcttttc aacttgactg aactagattt ctcccaaaac      240

aactttacta acattaagga ggtcgggctg gcaaacctaa cccagctcac aacgctgcat      300

ttggaggaaa atcagattac cgagatgact gattactgtc tacaagacct cagcaacctt      360

caagaactct acatcaacca caaccaaatt agcactattt ctgctcatgc ttttgcaggc      420

ttaaaaaatc tattaaggct ccacctgaac tccaacaaat tgaaagttat tgatagtcgc      480

tggtttgatt ctacacccaa cctggaaatt ctcatgatcg gagaaaaccc tgtgattgga      540

attctggata tgaacttcaa acccctcgca aatttgagaa gcttagtttt ggcaggaatg      600

tatctcactg atattcctgg aaatgctttg gtgggtctgg atagccttga gagcctgtct      660

ttttatgata acaaactggt taaagtccct caacttgccc tgcaaaaagt tccaagtttg      720

aaattcttag acctcaacaa aaaccccatt cacaaaatcc aagaagggga cttcaaaaat      780

atgcttcggt taaaagaact gggaatcaac aatatgggcg agctcgtttc tgtcgaccgc      840

tatgccctgg ataacttgcc tgaactcaca aagctggaag ccaccaataa ccctaaactc      900

tcttacatcc accgcttggc tttccgaagt gtccctgctc tggaaagctt gatgctgaac      960

aacaatgcct tgaatgccat ttaccaaaag acagtcgaat ccctccccaa tctgcgtgag     1020

atcagtatcc atagcaatcc cctcaggtgt gactgtgtga tccactggat taactccaac     1080

aaaaccaaca tccgcttcat ggagcccctg tccatgttct gtgccatgcc gcccgaatat     1140

aaagggcacc aggtgaagga agttttaatc caggattcga gtgaacagtg cctcccaatg     1200

atatctcacg acagcttccc aaatcgttta aacgtggata tcggcacgac ggttttccta     1260

gactgtcgag ccatggctga gccagaacct gaaatttact gggtcactcc cattggaaat     1320

aagataactg tggaaaccct ttcagataaa tacaagctaa gtagcgaagg taccttggaa     1380

atatctaaca tacaaattga agactcagga agatacacat gtgttgccca gaatgtccaa     1440

ggggcagaca ctcgggtggc aacaattaag gttaacggga cccttctgga tggtacccag     1500

gtgctaaaaa tatacgtcaa gcagacagaa tcccattcca tcttagtgtc ctggaaagtt     1560

aattccaatg tcatgacgtc aaacttaaaa tggtcgtctg ccaccatgaa gattgataac     1620

cctcacataa catatactgc cagggtccca gtcgatgtcc atgaatacaa cctaacgcat     1680

ctgcagcctt ccacagatta tgaagtgtgt ctcacagtgt ccaatattca tcagcagact     1740

caaaagtcat gcgtaaatgt cacaaccaaa aatgccgcct tcgcagtgga catctctgat     1800

caagaaacca gtacagcc                                                   1818


<210>  3971
<211>  1818
<212>  DNA
<213>  Homo Sapiens

<400>  3971
gtagataaaa aagtggattg tccacggtta tgtacgtgtg aaatcaggcc ttggtttaca       60

cccagatcca tttatatgga agcatctaca gtggattgta atgatttagg tcttttaact      120

ttcccagcca gattgccagc taacacacag attcttctcc tacagactaa caatattgca      180

aaaattgaat actccacaga ctttccagta aaccttacta gcctggattt atctcaaaac      240

aatttatctt cagtcaccaa tattaatgta aaaaagatgc ctcagctcct ttctgtgtac      300

ctagaggaaa acaaacttac tgaactgcct gaaaaatgtc tgtccgaact gagcaactta      360

caagaactct atattaatca caacttgctt tctacaattt cacctggagc ctttattggc      420

ctacataatc ttcttcgact tcatctcaat tcaaatagat tgcagatgat caacagtaag      480

tggtttgatg ctcttccaaa tctagagatt ctgatgattg gggaaaatcc aattatcaga      540

atcaaagaca tgaactttaa gcctcttatc aatcttcgca gcctggttat agctggtata      600

aacctcacag aaataccaga taacgccttg gttggactgg aaaacttaga aagcatctct      660

ttttacgata acaggcttat taaagtaccc catgttgctc ttcaaaaagt tgtaaatctc      720

aaatttttgg atctaaataa aaatcctatt aatagaatac gaaggggtga ttttagcaat      780

atgctacact taaaagagtt ggggataaat aatatgcctg agctgatttc catcgatagt      840

cttgctgtgg ataacctgcc agatttaaga aaaatagaag ctactaacaa ccctagattg      900

tcttacattc accccaatgc atttttcaga ctccccaagc tggaatcact catgctgaac      960

agcaatgctc tcagtgccct gtaccatggt accattgagt ctctgccaaa cctcaaggaa     1020

atcagcatac acagtaaccc catcaggtgt gactgtgtca tccgttggat gaacatgaac     1080

aaaaccaaca ttcgattcat ggagccagat tcactgtttt gcgtggaccc acctgaattc     1140

caaggtcaga atgttcggca agtgcatttc agggacatga tggaaatttg tctccctctt     1200

atagctcctg agagctttcc ttctaatcta aatgtagaag ctgggagcta tgtttccttt     1260

cactgtagag ctactgcaga accacagcct gaaatctact ggataacacc ttctggtcaa     1320

aaactcttgc ctaataccct gacagacaag ttctatgtcc attctgaggg aacactagat     1380

ataaatggcg taactcccaa agaagggggt ttatatactt gtatagcaac taacctagtt     1440

ggcgctgact tgaagtctgt tatgatcaaa gtggatggat cttttccaca agataacaat     1500

ggctctttga atattaaaat aagagatatt catgccaatt cagttttggt gtcctggaaa     1560

gcaagttcta aaattctcaa atctagtgtt aaatggacag cctttgtcaa gactgaaaat     1620

tctcatgctg cgcaaagtgc tcgaatacca tctgatgtca aggtatataa tcttactcat     1680

ctgaatccat caactgagta taaaatttgt attgatattc ccaccatcta tcagaaaaac     1740

agaaaaaaat gtgtaaatgt caccaccaaa ggtttgcacc ctgatcaaaa agagtatgaa     1800

aagaataata ccacaaca                                                   1818


<210>  3972
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  3972
gaccctcccc aggagaaggt cccgctcttc cgggtcactc agcagggccc ctgggggagc       60

agtggcagca acgccaccga ctcgccctgc gaggggctgc ccgccgcgga tgcgacggcc      120

ttgaccctgg cgaaccgcaa cctggagcgc ctgcccggct gcctaccgcg cacactgcgc      180

agcctcgacg ccagccacaa cctgctgcgc gccctgagca cttccgagct cggccacctg      240

gagcagctgc aggtgctgac cctgcgccac aaccgcatcg ccgcgctgcg ctggggcccg      300

ggtgggccgg cggggctgca caccctggac ctcagctaca accagctggc cgctctgctg      360

ccgtgcaccg ggcccgcgct gagcagcctc cgcgccctgg cgctcgccgg gaatccgctg      420

cgggcgctgc agccccgggc cttcgcctgc ttccccgcgc tgcaactcct caacctctcc      480

tgcaccgcgc tgggtcgcgg agcccagggg ggcatcgccg aggcggcgtt cgctggagag      540

gatggcgcgc ccctggtcac gctcgaagtc ctggatctca gcggcacgtt ccttgaacgg      600

gttgagtcag ggtggatcag agacctgccg aagctcacat ccctctacct gaggaagatg      660

cctcggctga cgaccctgga gggggacatt ttcaagatga cccccaacct gcagcagctg      720

gactgtcagg actccccagc acttgcttct gtcgccacac acatctttca agatactcca      780

catctacagg tccttctgtt ccagaactgc aacttgagtt ccttccctcc ttggaccctg      840

gattcctccc aggtcctatc gatcaacctc tttggcaacc ccctcacttg cagttgtgac      900

ttgtcttggc tcctcacgga tgcaaagaga actgtcctaa gcagggcagc agacactatg      960

tgcgcgccag ctgcgggatc cagcggcccc ttctcagcct ccctgtcact ctcccagctg     1020

cccggagtgt gccagtccga ccaaagcacc actctcgggg cttcacaccc accttgcttc     1080

aaccgctcca cctacgcaca gggtaccacc gtcgcgccca gcgcagcccc cgccacccgg     1140

cctgcgggag accagcagag tgtctccaag gcccctaacg tgggctctcg cacgatagct     1200

gcatggccgc acagcgatgc acgggagggg actgccccct ccacgaccaa ctctgtagca     1260

ggtcacagca actccagcgt tttccccagg gctgccagca ccaccaggac ccagcaccga     1320

ggagaacatg cccccgagct tgtccttgag cctgatatct cagctgcctc caccccactg     1380

gccagcaagc tcctgggccc cttccctacc tcgtgggacc gcagcataag ctcgcctcag     1440

cccggccaga ggacacacgc cacaccccaa gcccccaacc cgagtctttc cgagggcgag     1500

attccagtct tgctgctgga cgactacagt gaggaggagg aagggaggaa ggaggaggtg     1560

ggaacgcctc accaggacgt cccctgtgat taccatccct gcaagcacct gcagaccccg     1620

tgcgcggagc tgcagaggcg gtggcggtgc cggtgccccg gcctcagcgg ggaagacacc     1680

atcccagacc cgcccaggct gcagggggtg acggagacca cggacacgtc ggcgctggtc     1740

cactggtgtg cccccaactc ggtagtgcat gggtaccaga tccgctactc tgcggagggc     1800

tgggcgggga accagtcggt ggtgggggtc atctacgcca cggcccggca gcaccctctg     1860

tacgggctgt cgccgggcac cacctaccgc gtgtgcgtgc tggcggccaa cagggcgggc     1920

ttgagccagc cacggtcttc gggctggagg agcccgtgcg ccgccttcac caccaagccc     1980

agc                                                                   1983


<210>  3973
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  3973
ttggcccctc aagactttga agaagaggag gcagatgaga ctgagacggc gtggccgcct       60

ttgccggctg tcccctgcga ctacgaccac tgccgacacc tgcaggtgcc ctgcaaggag      120

ctacagaggg tcgggccggc ggcctgcctg tgcccaggac tctccagccc cgcccagccg      180

cccgacccgc cgcgcatggg agaagtgcgc attgcggccg aagagggccg cgcagtggtc      240

cactggtgtg cccccttctc cccggtcctc cactactggc tgctgctttg ggacggcagc      300

gaggctgcgc agaaggggcc cccgctgaac gctacggtcc gcagagccga actgaagggg      360

ctgaagccag ggggcattta tgtcgtttgc gtagtggccg ctaacgaggc cggggcaagc      420

cgcgtgcccc aggctggagg agagggcctc gagggggccg acatccctgc cttcgggcct      480

tgcagccgcc ttgcggtgcc gcccaacccc cgcact                                516


<210>  3974
<211>  1836
<212>  DNA
<213>  Homo Sapiens

<400>  3974
gctgtgcccg tggtaccctg gcatgttccc tgcccccctc agtgtgcctg ccagatccgg       60

ccctggtata cgccccgctc gtcctaccgc gaggctacca ctgtggactg caatgaccta      120

ttcctgacgg cagtcccccc ggcactcccc gcaggcacac agaccctgct cctgcagagc      180

aacagcattg tccgtgtgga ccagagtgag ctgggctacc tggccaatct cacagagctg      240

gacctgtccc agaacagctt ttcggatgcc cgagactgtg atttccatgc cctgccccag      300

ctgctgagcc tgcacctaga ggagaaccag ctgacccggc tggaggacca cagctttgca      360

gggctggcca gcctacagga actctatctc aaccacaacc agctctaccg catcgccccc      420

agggcctttt ctggcctcag caacttgctg cggctgcacc tcaactccaa cctcctgagg      480

gccattgaca gccgctggtt tgaaatgctg cccaacttgg agatactcat gattggcggc      540

aacaaggtag atgccatcct ggacatgaac ttccggcccc tggccaacct gcgtagcctg      600

gtgctagcag gcatgaacct gcgggagatc tccgactatg ccctggaggg gctgcaaagc      660

ctggagagcc tctccttcta tgacaaccag ctggcccggg tgcccaggcg ggcactggaa      720

caggtgcccg ggctcaagtt cctagacctc aacaagaacc cgctccagcg ggtagggccg      780

ggggactttg ccaacatgct gcaccttaag gagctgggac tgaacaacat ggaggagctg      840

gtctccatcg acaagtttgc cctggtgaac ctccccgagc tgaccaagct ggacatcacc      900

aataacccac ggctgtcctt catccacccc cgcgccttcc accacctgcc ccagatggag      960

accctcatgc tcaacaacaa cgctctcagt gccttgcacc agcagacggc ggagtccctg     1020

cccaacctgc aggaggtagg tctccacggc aaccccatcc gctgtgactg tgtcatccgc     1080

tgggccaatg ccacgggcac ccgtgtccgc ttcatcgagc cgcaatccac cctgtgtgcg     1140

gagcctccgg acctccagcg cctcccggtc cgtgaggtgc ccttccggga gatgacggac     1200

cactgtttgc ccctcatctc cccacgaagc ttccccccaa gcctccaggt agccagtgga     1260

gagagcatgg tgctgcattg ccgggcactg gccgaacccg aacccgagat ctactgggtc     1320

actccagctg ggcttcgact gacacctgcc catgcaggca ggaggtaccg ggtgtacccc     1380

gaggggaccc tggagctgcg gagggtgaca gcagaagagg cggggctata cacctgtgtg     1440

gcccagaacc tggtgggggc tgacactaag acggttagtg tggttgtggg ccgtgctctc     1500

ctccagccag gcagggacga aggacagggg ctggagctcc gggtgcagga gacccacccc     1560

tatcacatcc tgctatcttg ggtcacccca cccaacacag tgtccaccaa cctcacctgg     1620

tccagtgcct cctccctccg gggccagggg gccacagctc tggcccgcct gcctcgggga     1680

acccacagct acaacattac ccgcctcctt caggccacgg agtactgggc ctgcctgcaa     1740

gtggcctttg ctgatgccca cacccagttg gcttgtgtat gggccaggac caaagaggcc     1800

acttcttgcc acagagcctt aggggaccgt cctggg                               1836


<210>  3975
<211>  1179
<212>  DNA
<213>  Homo Sapiens

<400>  3975
gcccccagcg ggtgcccgca gctgtgccgg tgcgaggggc ggctgctgta ctgcgaggcg       60

ctcaacctca ccgaggcgcc ccacaacctg tccggcctgc tgggcttgtc cctgcgctac      120

aacagcctct cggagctgcg cgccggccag ttcacggggt taatgcagct cacgtggctc      180

tatctggatc acaatcacat ctgctccgtg cagggggacg cctttcagaa actgcgccga      240

gttaaggaac tcacgctgag ttccaaccag atcacccaac tgcccaacac caccttccgg      300

cccatgccca acctgcgcag cgtggacctc tcgtacaaca agctgcaggc gctcgcgccc      360

gacctcttcc acgggctgcg gaagctcacc acgctgcata tgcgggccaa cgccatccag      420

tttgtgcccg tgcgcatctt ccaggactgc cgcagcctca agtttctcga catcggatac      480

aatcagctca agagtctggc gcgcaactct ttcgccggct tgtttaagct caccgagctg      540

cacctcgagc acaacgactt ggtcaaggtg aacttcgccc acttcccgcg cctcatctcc      600

ctgcactcgc tctgcctgcg gaggaacaag gtggccattg tggtcagctc gctggactgg      660

gtttggaacc tggagaaaat ggacttgtcg ggcaacgaga tcgagtacat ggagccccat      720

gtgttcgaga ccgtgccgca cctgcagtcc ctgcagctgg actccaaccg cctcacctac      780

atcgagcccc ggatcctcaa ctcttggaag tccctgacaa gcatcaccct ggccgggaac      840

ctgtgggatt gcgggcgcaa cgtgtgtgcc ctagcctcgt ggctcagcaa cttccagggg      900

cgctacgatg gcaacttgca gtgcgccagc ccggagtacg cacagggcga ggacgtcctg      960

gacgccgtgt acgccttcca cctgtgcgag gatggggccg agcccaccag cggccacctg     1020

ctctcggccg tcaccaaccg cagtgatctg gggccccctg ccagctcggc caccacgctc     1080

gcggacggcg gggaggggca gcacgacggc acattcgagc ctgccaccgt ggctcttcca     1140

ggcggcgagc acgccgagaa cgccgtgcag atccacaag                            1179


<210>  3976
<211>  1167
<212>  DNA
<213>  Homo Sapiens

<400>  3976
tgtccaccca aatgccgctg cgagaagctg ctcttctact gcgactctca gggcttccac       60

tcagtgccaa acgccacaga caagggctct ctgggcctgt ccctgaggca caatcacatc      120

acagagctcg aaagagatca atttgccagc ttcagtcaac ttacttggct ccacttagat      180

cacaatcaaa tttcaacagt aaaagaagat gcttttcaag gactatataa acttaaggaa      240

ttaatcttaa gttccaacaa aatattttac ttgccaaaca caacttttac ccaactgatt      300

aacctgcaaa atttggacct gtcttttaat cagctgtcat ctctgcaccc agagctcttc      360

tatggccttc ggaagctgca gaccttgcat ttacgttcca actccctgcg gactatccca      420

gtacgcctgt tctgggactg tcgtagtctg gagtttctgg atttgagcac aaatcgtttg      480

cgaagtttgg ctcgcaatgg atttgcagga ttaattaaac tgagagagct tcacctagag      540

cacaaccagc tgacgaagat taattttgct catttcctac ggctaagcag tctgcacacg      600

ctcttcttac aatggaacaa aatcagcaac ttgacatgtg ggatggagtg gacctggggc      660

actttagaaa agctagacct gactggaaat gaaatcaaag ccatcgactt gacagtgttt      720

gaaacgatgc ccaatcttaa aatactcctc atggataaca acaagttaaa cagccttgat      780

tccaagatct taaactccct gagatccctc acaaccgttg gtctctctgg caatctgtgg      840

gaatgcagcg cccgaatatg tgctctggcc tcctggctgg gcagtttcca aggtcggtgg      900

gaacactcca tcctatgcca cagtcctgac cacacccaag gagaggatat tctagatgca      960

gtccatggat ttcagctctg ctggaatttg tcaaccactg tcactgtcat ggctacaact     1020

tatagagatc caaccactga atatacaaaa agaataagct catcaagtta ccatgtggga     1080

gacaaagaaa tcccaactac tgcaggcata gcagttacta ccgaggaaca ctttcctgaa     1140

ccagacaatg ccatcttcac tcagcgg                                         1167


<210>  3977
<211>  1167
<212>  DNA
<213>  Homo Sapiens

<400>  3977
gaacgaggat gccctaaggg ctgtaggtgt gaaggcaaaa tggtatattg tgaatctcag       60

aaattacagg agataccctc aagtatatct gctggttgct taggtttgtc ccttcgctat      120

aacagccttc aaaaacttaa gtataatcaa tttaaagggc tcaaccagct cacctggcta      180

taccttgacc ataaccatat cagcaatatt gacgaaaatg cttttaatgg aatacgcaga      240

ctcaaagagc tgattcttag ttccaataga atctcctatt ttcttaacaa taccttcaga      300

cctgtgacaa atttacggaa cttggatctg tcctataatc agctgcattc tctgggatct      360

gaacagtttc ggggcttgcg gaagctgctg agtttacatt tacggtctaa ctccctgaga      420

accatccctg tgcgaatatt ccaagactgc cgcaacctgg aacttttgga cctgggatat      480

aaccggatcc gaagtttagc caggaatgtc tttgctggca tgatcagact caaagaactt      540

cacctggagc acaatcaatt ttccaagctc aacctggccc tttttccaag gttggtcagc      600

cttcagaacc tttacttgca gtggaataaa atcagtgtca taggacagac catgtcctgg      660

acctggagct ccttacaaag gcttgattta tcaggcaatg agatcgaagc tttcagtgga      720

cccagtgttt tccagtgtgt cccgaatctg cagcgcctca acctggattc caacaagctc      780

acatttattg gtcaagagat tttggattct tggatatccc tcaatgacat cagtcttgct      840

gggaatatat gggaatgcag cagaaatatt tgctcccttg taaactggct gaaaagtttt      900

aaaggtctaa gggagaatac aattatctgt gccagtccca aagagctgca aggagtaaat      960

gtgatcgatg cagtgaagaa ctacagcatc tgtggcaaaa gtactacaga gaggtttgat     1020

ctggccaggg ctctcccaaa gccgacgttt aagcccaagc tccccaggcc gaagcatgag     1080

agcaaacccc ctttgccccc gacggtggga gccacagagc ccggcccaga gaccgatgct     1140

gacgccgagc acatctcttt ccataaa                                         1167


<210>  3978
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  3978
cagagagctt gcccaaagaa ctgcagatgt gatggcaaaa ttgtgtactg tgagtctcat       60

gctttcgcag atatccctga gaacatttct ggagggtcac aaggcttatc attaaggttc      120

aacagcattc agaagctcaa atccaatcag tttgccggcc ttaaccagct tatatggctt      180

tatcttgacc ataattacat tagctcagtg gatgaagatg catttcaagg gatccgtaga      240

ctgaaagaat taattctaag ctccaacaaa attacttatc tgcacaataa aacatttcac      300

ccagttccca atctccgcaa tctggacctc tcctacaata agcttcagac attgcaatct      360

gaacaattta aaggccttcg gaaactcatc attttgcact tgagatctaa ctcactaaag      420

actgtgccca taagagtttt tcaagactgt cggaatcttg attttttgga tttgggttac      480

aatcgtcttc gaagcttgtc ccgaaatgca tttgctggcc tcttgaagtt aaaggagctc      540

cacctggagc acaaccagtt ttccaagatc aactttgctc attttccacg tctcttcaac      600

ctccgctcaa tttacttaca atggaacagg attcgctcca ttagccaagg tttgacatgg      660

acttggagtt ccttacacaa cttggattta tcagggaatg acatccaagg aattgagccg      720

ggcacattta aatgcctccc caatttacaa aaattgaatt tggattccaa caagctcacc      780

aatatctcac aggaaactgt caatgcgtgg atatcattaa tatccatcac attgtctgga      840

aatatgtggg aatgcagtcg gagcatttgt cctttatttt attggcttaa gaatttcaaa      900

ggaaataagg aaagcaccat gatatgtgcg ggacctaagc acatccaggg tgaaaaggtt      960

agtgatgcag tggaaacata taatatctgt tctgaagtcc aggtggtcaa cacagaaaga     1020

tcacacctgg tgccccaaac tccccagaaa cctctgatta tccctagacc taccatcttc     1080

aaacctgacg tcacccaatc cacctttgaa acaccaagcc cttccccagg gtttcagatt     1140

cctggcgcag agcaagagta tgagcatgtt tcatttcaca aa                        1182


<210>  3979
<211>  783
<212>  DNA
<213>  Homo Sapiens

<400>  3979
cagtcatcta caaattttgt agactgcagc cagcagggtc tggccgaaat cccttcccat       60

ttacctcctc agactcgaac gctgcattta caagataatc agatacacca tcttcctgct      120

tttgcattta ggtcagtgcc atggctcatg accttaaact tgtccaacaa ttccctttca      180

aatctggccc ctggagcttt ccatgggctt cagcacttgc aggttttaaa tctaacccag      240

aattcactcc tttccctgga aagcagactt ttccattccc tccctcagct gagggagctt      300

gatttgtcat caaacaacat aagccacctt cccacatcct tgggagagac ttgggagaac      360

ctaactatac ttgcggttca acaaaaccag cttcagcagc ttgatcgagc gctcctggaa      420

tccatgccca gtgtgaggct tttacttctc aaggacaacc tctggaaatg caattgccac      480

ttgctcggtc ttaaactctg gctggagaaa tttgtctata aagggggact aacagacggc      540

atcatctgtg aatcaccaga cacctggaag ggaaaggacc tccttaggat ccctcatgag      600

ctgtaccagc cctgccctct tcctgctcct gatccagtgt cctcgcaggc tcagtggccc      660

ggctctgccc acggtgtggt cctgaggcct cctgagaacc acaacgcggg ggagcgagaa      720

ctcttggagt gcgagctcaa acccaagcca aggccggcca acctgcgtca tgccattgcc      780

act                                                                    783


<210>  3980
<211>  825
<212>  DNA
<213>  Homo Sapiens

<400>  3980
ctccccacct gccctttctc ctgcaagtgt gacagccgca gcctggaggt ggactgcagt       60

ggccttggcc tcaccacggt gcccccagac gtgcccgcag ccacccgaac cctcttgctc      120

ttgaacaata agctgagtgc cctgccaagc tgggctttcg ccaacctctc cagcctgcag      180

cggttggacc tgtccaacaa cttcctggac cggctgcccc gctccatttt cggggacctg      240

acgaatctga ctgagcttca gctgcgcaat aacagcatca ggaccctgga cagggacctg      300

ctgcggcact cgccgctgct ccgccacctg gacctgtcca tcaacggcct ggcccagttg      360

ccccctggtc ttttcgacgg gctcctggct ctgcgctccc tctcgcttcg ctccaaccgt      420

ctgcagaatc tggaccggct gacatttgaa cccctagcaa acctgcagct gctgcaggtc      480

ggggataacc cctgggagtg tgactgtaac ctgcgtgagt tcaaacactg gatggagtgg      540

ttctcctacc gagggggacg cttggaccag cttgcctgca ccctgcccaa ggagctgagg      600

gggaaggaca tgcggatggt ccccatggag atgttcaact actgctccca gctggaggac      660

gagaatagct cagctgggct ggatattcct gggccaccct gcaccaaggc cagtccagag      720

cctgctaagc ccaagcccgg ggctgagccg gagccggagc ccagcacagc ctgcccacag      780

aagcagaggc accggccggc gagcgtgagg cgagccatgg gcacg                      825


<210>  3981
<211>  861
<212>  DNA
<213>  Homo Sapiens

<400>  3981
gttcgcagcg tggattttaa ccgaggcacg gacaacatca ccgtgaggca gggggacaca       60

gccatcctca ggtgcgttgt agaagacaag aactcaaagg tggcctggtt gaaccgttct      120

ggcatcattt ttgctggaca tgacaagtgg tctctggacc cacgggttga gctggagaaa      180

cgccattctc tggaatacag cctccgaatc cagaaggtgg atgtctatga tgagggttcc      240

tacacttgct cagttcagac acagcatgag cccaagacct cccaagttta cttgatcgta      300

caagtcccac caaagatctc caatatctcc tcggatgtca ctgtgaatga gggcagcaac      360

gtgactctgg tctgcatggc caatggccgt cctgaacctg ttatcacctg gagacacctt      420

acaccaactg gaagggaatt tgaaggagaa gaagaatatc tggagatcct tggcatcacc      480

agggagcagt caggcaaata tgagtgcaaa gctgccaacg aggtctcctc ggcggatgtc      540

aaacaagtca aggtcactgt gaactatcct cccactatca cagaatccaa gagcaatgaa      600

gccaccacag gacgacaagc ttcactcaaa tgtgaggcct cggcagtgcc tgcacctgac      660

tttgagtggt accgggatga cactaggata aatagtgcca atggccttga gattaagagc      720

acggagggcc agtcttccct gacggtgacc aacgtcactg aggagcacta cggcaactac      780

acctgtgtgg ctgccaacaa gctgggggtc accaatgcca gcctagtcct tttcagacct      840

gggtcggtga gaggaataaa t                                                861


<210>  3982
<211>  777
<212>  DNA
<213>  Homo Sapiens

<400>  3982
atgcaacagg acggacttgg agtagggaca aggaacggaa gtgggaaggg gaggagcgtg       60

cacccctcct ggccttggtg cgcgccgcgc cccctaaggt actttggaag ggacgcgcgg      120

gccagacgcg cccagacggc cgcgatggcg ctgttggccg gcgggctctc cagagggctg      180

ggctcccacc cggccgccgc aggccgggac gcggtcgtct tcgtgtggct tctgcttagc      240

acctggtgca cagctcctgc cagggccatc caggtgaccg tgtccaaccc ctaccacgtg      300

gtgatcctct tccagcctgt gaccctgccc tgtacctacc agatgacctc gacccccacg      360

caacccatcg tcatctggaa gtacaagtct ttctgccggg accgcatcgc cgatgccttc      420

tccccggcca gcgtcgacaa ccagctcaat gcccagctgg cagccgggaa cccaggctac      480

aacccctacg ttgagtgcca ggacagcgtg cgcaccgtca gggtcgtggc caccaagcag      540

ggcaacgctg tgaccctggg agattactac cagggccgga ggattaccat caccggaaat      600

gctgacctga cctttgacca gacggcgtgg ggggacagtg gtgtgtatta ctgctccgtg      660

gtctcagccc aggacctcca ggggaacaat gaggcctacg cagagctcat cgtccttggg      720

aggacctcag gggtggctga gctcttacct ggttttcagg cggggcccat agaagac         777


<210>  3983
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  3983
ctccctggtg ttggcctcac accttcagct gcccagactg cccgtcagca ccccaagatg       60

catcttgccc acagcaccct caaacctgct gctcacctca ttggagaccc cagcaagcag      120

aactcactgc tctggagagc aaacacggac cgtgccttcc tccaggatgg tttctccttg      180

agcaacaatt ctctcctggt ccccaccagt ggcatctact tcgtctactc ccaggtggtc      240

ttctctggga aagcctactc tcccaaggcc acctcctccc cactctacct ggcccatgag      300

gtccagctct tctcctccca gtaccccttc catgtgcctc tcctcagctc ccagaagatg      360

gtgtatccag ggctgcagga accctggctg cactcgatgt accacggggc tgcgttccag      420

ctcacccagg gagaccagct atccacccac acagatggca tcccccacct agtcctcagc      480

cctagtactg tcttctttgg agccttcgct ctg                                   513


<210>  3984
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  3984
caggatcagg gaggactggt aacggagacg gccgaccccg gggcacaggc ccagcaagga       60

ctggggtttc agaagctgcc agaggaggag ccagaaacag atctcagccc cgggctccca      120

gctgcccacc tcataggcgc tccgctgaag gggcaggggc taggctggga gacgacgaag      180

gaacaggcgt ttctgacgag cgggacgcag ttctcggacg ccgaggggct ggcgctcccg      240

caggacggcc tctattacct ctactgtctc gtcggctacc ggggccgggc gccccctggc      300

ggcggggacc cccagggccg ctcggtcacg ctgcgcagct ctctgtaccg ggcggggggc      360

gcctacgggc cgggcactcc cgagctgctg ctcgagggcg ccgagacggt gactccagtg      420

ctggacccgg ccaggagaca agggtacggg cctctctggt acacgagcgt ggggttcggc      480

ggcctggtgc agctccggag gggcgagagg gtgtacgtca acatcagtca ccccgatatg      540

gtggacttcg cgagagggaa gaccttcttt ggggccgtga tggtgggg                   588


<210>  3985
<211>  4125
<212>  DNA
<213>  Homo Sapiens

<400>  3985
aaccacactg gccgcatcaa ggtggtcttt actccgagca tctgtaaagt gacctgcacc       60

aagggcagct gtcagaacag ctgtgagaag gggaacacca ccactctcat tagtgagaat      120

ggtcatgctg ccgacaccct gacggccacg aacttccgag tggtaatttg ccatcttcca      180

tgtatgaatg gtggccagtg cagttcaagg gacaaatgtc agtgccctcc aaatttcaca      240

ggaaaacttt gtcagatccc agtccatggt gccagcgtgc ctaaacttta tcagcattcc      300

cagcagccag gcaaggcgtt ggggacgcat gtcatccatt caacacatac cttgcctctg      360

accgtgacta gccagcaagg agtcaaagtg aaatttcctc ctaacatagt caatatccat      420

gtgaaacatc ctcctgaagc ttccgtccag atacatcagg tttcaagaat tgatggccca      480

acaggccaga agacaaaaga agctcaacca ggccaatccc aagtctcgta ccaagggctt      540

cctgtccaga agacccagac catacattcc acatactccc accagcaggt cattcctcac      600

gtctaccccg tggctgctaa gacacagctt ggccggtgct tccaggaaac cattgggtca      660

cagtgtggca aagcgctccc tggcctttca aagcaagagg actgctgtgg aactgtgggt      720

acctcctggg gctttaacaa atgccagaaa tgccccaaga aaccatctta tcatggatac      780

aaccaaatga tggaatgcct accgggttat aagcgggtta acaacacctt ttgccaagat      840

attaatgaat gtcagctaca aggtgtatgc cctaatggtg agtgtttgaa taccatgggc      900

agctatcgat gtacctgcaa aataggattt gggccggatc ctaccttttc aagttgtgtt      960

cctgatcccc ctgtgatctc ggaagagaaa gggccctgtt accgacttgt cagttctgga     1020

agacagtgta tgcaccctct gtctgttcac ctcaccaagc agctctgctg ttgtagtgtg     1080

ggcaaggcct ggggcccaca ctgtgagaaa tgtccccttc caggcacagc tgcttttaag     1140

gaaatctgtc ctggtggaat gggttatacg gtttctggcg ttcatagacg caggccaatc     1200

catcaccatg taggtaaagg acctgtattt gtcaagccaa agaacactca acctgttgct     1260

aaaagtactc atcctccacc tctcccagcc aaggaagagc cagtggaggc cctgaccttc     1320

tcccgggaac acgggccagg agtggcggag ccagaagtgg caactgcacc ccctgaaaag     1380

gaaatacctt cattggatca agagaaaacc aaacttgagc ctggtcaacc ccagctgtct     1440

ccaggcattt ccactattca tctgcatcca cagtttccag tagtgattga aaaaacatca     1500

cctcctgtgc ctgttgaagt agctcctgaa gcttctacgt ctagtgccag ccaagtgatt     1560

gctcctactc aagtgacaga aatcaatgaa tgtactgtga accctgatat ctgtggagca     1620

ggacactgca ttaacctacc agtgagatat acctgtatat gctacgaggg ctacaggttc     1680

agtgaacaac agaggaaatg tgtggatatt gatgagtgta ctcaggtcca acacctctgc     1740

tcccagggcc gctgtgaaaa caccgaggga agtttcttgt gcatttgccc agcaggattt     1800

atggccagtg aggagggtac taactgcata gatgttgacg aatgcctgag gccggacgtc     1860

tgtggggagg ggcactgtgt caatactgtg ggggccttcc ggtgtgaata ctgtgacagc     1920

gggtaccgca tgactcagag aggccgttgt gaggatattg atgaatgttt gaatccaagc     1980

acttgtccag atgagcagtg tgtgaattct cctggatctt accagtgcgt tccctgcaca     2040

gaaggattcc gaggctggaa tggacagtgc cttgatgtgg acgagtgcct ggaaccaaac     2100

gtctgcgcaa atggtgattg ttccaacctt gaaggctcct acatgtgttc atgccacaaa     2160

ggctataccc ggactccgga ccacaagcac tgtagagata ttgatgaatg tcagcaaggg     2220

aatctatgtg taaacgggca gtgcaaaaat accgagggct ccttcaggtg cacctgtgga     2280

caggggtacc agctgtcggc agctaaagac cagtgtgaag acattgatga atgccagcac     2340

cgtcatctct gtgctcatgg gcagtgcagg aacactgagg gctcttttca atgtgtgtgt     2400

gaccagggtt acagagcatc tgggcttgga gaccactgtg aagatatcaa tgaatgcttg     2460

gaggacaaga gtgtttgcca gagaggagac tgcattaata ctgcagggtc ctatgattgt     2520

acttgtccgg atggatttca gctagatgac aataaaacat gtcaagatat taatgaatgt     2580

gaacatccag ggctctgtgg tccgcaaggg gagtgcctaa acacagaggg ttctttccat     2640

tgtgtctgcc agcagggttt ctcaatctct gcagatggcc gtacgtgtga agatattgat     2700

gaatgtgtaa acaacactgt ttgtgacagt cacgggtttt gtgacaatac agctggctcc     2760

ttccgctgcc tctgttatca gggctttcaa gccccacagg atgggcaagg gtgtgtggat     2820

gtgaatgaat gtgaactgct cagtggggtg tgtggtgaag ccttctgtga aaacgtggaa     2880

gggtccttcc tgtgcgtgtg tgctgatgaa aaccaagagt acagccccat gactgggcag     2940

tgccgctccc ggacctccac agatttagat gtagatgtag atcaacccaa agaagaaaag     3000

aaagaatgct actataatct caatgacgcc agtctctgtg ataatgtgtt ggcccccaat     3060

gtcacgaaac aagaatgctg ctgtacatca ggcgcgggat ggggagataa ctgcgaaatc     3120

ttcccctgcc cggtcttggg aactgctgag ttcactgaaa tgtgtcccaa agggaaaggt     3180

tttgtgcctg ctggagaatc atcttctgaa gctggtggtg agaactataa agatgcagat     3240

gaatgcctac tttttggaca agaaatctgc aaaaatggtt tctgtttgaa cactcggcct     3300

gggtatgaat gctactgtaa gcaagggacg tactatgatc ctgtgaaact gcagtgcttt     3360

gatatggatg aatgtcaaga ccccagtagt tgtattgatg gccagtgtgt taatacagag     3420

ggctcttaca actgcttctg tactcacccc atggtcctgg atgcgtcaga aaaaagatgt     3480

atacgaccgg ctgagtcaaa cgaacaaata gaagaaactg atgtctacca agatttgtgc     3540

tgggaacatc tgagtgatga atacgtgtgt agccggcctc ttgtgggcaa gcagacaacg     3600

tacactgagt gctgctgtct gtatggagag gcctggggca tgcagtgtgc cctctgcccc     3660

ctgaaggatt cagatgacta tgctcagctg tgtaacatcc ccgtgacggg acgccggcag     3720

ccatatggac gggacgcctt ggttgacttc agtgaacagt atactccaga agccgatccc     3780

tacttcatcc aagaccgttt tctaaatagc tttgaggagt tacaggctga ggaatgcggc     3840

atcctcaatg gatgtgaaaa tggtcgctgt gtgagggtcc aggaaggtta cacctgcgat     3900

tgctttgatg ggtatcactt ggatacggcc aagatgacct gtgtcgatgt aaatgaatgc     3960

gatgagttga acaaccggat gtctctctgc aagaatgcca agtgcattaa caccgatggt     4020

tcctacaagt gtttgtgtct gccaggctac gtgccttctg acaagccaaa ctactgcact     4080

ccgttgaata ccgccttgaa tttagagaaa gacagtgacc tggag                     4125


<210>  3986
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  3986
caggcggtgc ctccatatgc gtcggagaac cagacctgca gggaccagga aaaggaatac       60

tatgagcccc agcaccgcat ctgctgctcc cgctgcccgc caggcaccta tgtctcagct      120

aaatgtagcc gcatccggga cacagtttgt gccacatgtg ccgagaattc ctacaacgag      180

cactggaact acctgaccat ctgccagctg tgccgcccct gtgacccagt gatgggcctc      240

gaggagattg ccccctgcac aagcaaacgg aagacccagt gccgctgcca gccgggaatg      300

ttctgtgctg cctgggccct cgagtgtaca cactgcgagc tactttctga ctgcccgcct      360

ggcactgaag ccgagctcaa agatgaagtt gggaagggta acaaccactg cgtcccctgc      420

aaggccgggc acttccagaa tacctcctcc cccagcgccc gctgccagcc ccacaccagg      480

tgtgagaacc aaggtctggt ggaggcagct ccaggcactg cccagtccga cacaacctgc      540

aaaaatccat tagagccact gcccccagag atgtcaggaa ccatgctgat g               591


<210>  3987
<211>  2076
<212>  DNA
<213>  Homo Sapiens

<400>  3987
ggccgtagga gaaggagtgt tcagtggtgc gccgtatccc aacccgaggc cacaaaatgc       60

ttccaatggc aaaggaatat gagaaaagtg cgtggccctc ctgtcagctg cataaagaga      120

gactccccca tccagtgtat ccaggccatt gcggaaaaca gggccgatgc tgtgaccctt      180

gatggtggtt tcatatacga ggcaggcctg gccccctaca aactgcgacc tgtagcggcg      240

gaagtctacg ggaccgaaag acagccacga actcactatt atgccgtggc tgtggtgaag      300

aagggcggca gctttcagct gaacgaactg caaggtctga agtcctgcca cacaggcctt      360

cgcaggaccg ctggatggaa tgtccctata gggacacttc gtccattctt gaattggacg      420

ggtccacctg agcccattga ggcagctgtg gccaggttct tctcagccag ctgtgttccc      480

ggtgcagata aaggacagtt ccccaacctg tgtcgcctgt gtgcggggac aggggaaaac      540

aaatgtgcct tctcctccca ggaaccgtac ttcagctact ctggtgcctt caagtgtctg      600

agagacgggg ctggagacgt ggcttttatc agagagagca cagtgtttga ggacctgtca      660

gacgaggctg aaagggacga gtatgagtta ctctgcccag acaacactcg gaagccagtg      720

gacaagttca aagactgcca tctggcccgg gtcccttctc atgccgttgt ggcacgaagt      780

gtgaatggca aggaggatgc catctggaat cttctccgcc aggcacagga aaagtttgga      840

aaggacaagt caccgaaatt ccagctcttt ggctccccta gtgggcagaa agatctgctg      900

ttcaaggact ctgccattgg gttttcgagg gtgcccccga ggatagattc tgggctgtac      960

cttggctccg gctacttcac tgccatccag aacttgagga aaagtgagga ggaagtggct     1020

gcccggcgtg cgcgggtcgt gtggtgtgcg gtgggcgagc aggagctgcg caagtgtaac     1080

cagtggagtg gcttgagcga aggcagcgtg acctgctcct cggcctccac cacagaggac     1140

tgcatcgccc tggtgctgaa aggagaagct gatgccatga gtttggatgg aggatatgtg     1200

tacactgcag gcaaatgtgg tttggtgcct gtcctggcag agaactacaa atcccaacaa     1260

agcagtgacc ctgatcctaa ctgtgtggat agacctgtgg aaggatatct tgctgtggcg     1320

gtggttagga gatcagacac tagccttacc tggaactctg tgaaaggcaa gaagtcctgc     1380

cacaccgccg tggacaggac tgcaggctgg aatatcccca tgggcctgct cttcaaccag     1440

acgggctcct gcaaatttga tgaatatttc agtcaaagct gtgcccctgg gtctgacccg     1500

agatctaatc tctgtgctct gtgtattggc gacgagcagg gtgagaataa gtgcgagccc     1560

aacagcaacg agagatacta cggctacact ggggctttcc ggtgcctggc tgagaatgct     1620

ggagacgttg catttgtgaa agatgtcact gtcttgcaga acactgatgg aaataacaat     1680

gaggcatggg ctaaggattt gaagctggca gactttgcgc tgctgtgcct cgatggcaaa     1740

cggaagcctg tgactgaggc tagaagctgc catcttgcca tggccccgaa tcatgccgtg     1800

gtgtctcgga tggataaggt ggaacgcctg aaacaggtgc tgctccacca acaggctaaa     1860

tttgggagaa atggatctga ctgcccggac aagttttgct tattccagtc tgaaaccaaa     1920

aaccttctgt tcaatgacaa cactgagtgt ctggccagac tccatggcaa aacaacatat     1980

gaaaaatatt tgggaccaca gtatgtcgca ggcattacta atctgaaaaa gtgctcaacc     2040

tcccccctcc tggaagcctg tgaattcctc aggaag                               2076


<210>  3988
<211>  1224
<212>  DNA
<213>  Homo Sapiens

<400>  3988
attctctgct ctagcccggg gtcccaggag acttttctgc ggtcctcgcc cctgccgctg       60

gcaagcccca gcccccggga cccgaaagtc agcgccccgc ctagtatctt ggagccagcc      120

tccccgctga attctccggg caccgagggg tcttggctgt tttctacctg cggggccagc      180

ggccggcatg ggcccacaca gacacaatgt gacggggcgt acgcggggac cagcgtggtg      240

gtgaccgtgg gggccgccgg gcagctgaga ggcgtgcagc tgtggcgcgt gccgggccct      300

ggccagtatc tgatctcagc ctacggagcc gcgggcggca aaggcgccaa gaaccacctg      360

tcgcgggcgc atggcgtctt cgtctcagca atcttctccc tcggtctcgg ggagtcgctg      420

tacatcctgg tggggcagca gggagaggac gcctgtcccg gaggtagccc ggagagccag      480

ctcgtctgcc tcggggagtc tcgagccgtt gaagagcacg cggcgatgga tgggagcgaa      540

ggggtcccgg ggtcgcggcg ctgggcggga ggtggcgggg gtggcggggg cgccacctac      600

gttttccggg tgcgcgctgg cgagctggaa ccgttgctgg tggcggccgg aggcggcggt      660

cgggcctacc tgaggccgcg ggaccgaggc cggactcagg cctcccccga gaaactggag      720

aaccgctcgg aggcgcccgg gagcggcggg agaggcgggg cggcaggtgg tgggggcggc      780

tggacgtcgc gggctccctc tccgcaggcc ggccgctcac tgcaggaggg ggcggagggc      840

ggccagggct gctccgaggc ttgggcgacc cttggctggg ccgcggccgg cggcttcggg      900

ggcggcggcg gggcctgcac tgcgggcgga ggcggtggcg gctacagggg gggcgacgct      960

tcagagactg acaacctctg ggctgatggg gaagatggag tatccttcat acaccccagc     1020

agcgagctct tcctgcagcc tctggcagtc accgagaacc acggagaggt agagatccga     1080

aggcacctca actgcagtca ctgccctttg agagactgcc aatggcaggc agagctccag     1140

ctggctgaat gcctgtgccc agaaggcatg gagctagctg tggataacgt cacctgcatg     1200

gacctgcgca agcccccagg ccct                                            1224


<210>  3989
<211>  960
<212>  DNA
<213>  Homo Sapiens

<400>  3989
cagtactatg attatgattt tcccctatca atttatgggc aatcatcacc aaactgtgca       60

ccagaatgta actgccctga aagctaccca agtgccatgt actgtgatga gctgaaattg      120

aaaagtgtac caatggtgcc tcctggaatc aagtatcttt accttaggaa taaccagatt      180

gaccatattg atgaaaaggc ctttgagaat gtaactgatc tgcagtggct cattctagat      240

cacaaccttc tagaaaactc caagataaaa gggagagttt tctctaaatt gaaacaactg      300

aagaagctgc atataaacca caacaacctg acagagtctg tgggcccact tcccaaatct      360

ctggaggatc tgcagcttac tcataacaag atcacaaagc tgggctcttt tgaaggattg      420

gtaaacctga ccttcatcca tctccagcac aatcggctga aagaggatgc tgtttcagct      480

gcttttaaag gtcttaaatc actcgaatac cttgacttga gcttcaatca gatagccaga      540

ctgccttctg gtctccctgt ctctcttcta actctctact tagacaacaa taagatcagc      600

aacatccctg atgagtattt caagcgtttt aatgcattgc agtatctgcg tttatctcac      660

aacgaactgg ctgatagtgg aatacctgga aattctttca atgtgtcatc cctggttgag      720

ctggatctgt cctataacaa gcttaaaaac ataccaactg tcaatgaaaa ccttgaaaac      780

tattacctgg aggtcaatca acttgagaag tttgacataa agagcttctg caagatcctg      840

gggccattat cctactccaa gatcaagcat ttgcgtttgg atggcaatcg catctcagaa      900

accagtcttc caccggatat gtatgaatgt ctacgtgttg ctaacgaagt cactcttaat      960


<210>  3990
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  3990
ctgcgctgcc acgtgtgcac cagctccagc aactgcaagc attctgtggt ctgcccggcc       60

agctctcgct tctgcaagac cacgaacaca gtggagcctc tgagggggaa tctggtgaag      120

aaggactgtg cggagtcgtg cacacccagc tacaccctgc aaggccaggt cagcagcggc      180

accagctcca cccagtgctg ccaggaggac ctgtgcaatg agaagctgca caac            234


<210>  3991
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  3991
ctgatgtgct tctcctgctt gaaccagaag agcaatctgt actgcctgaa gccgaccatc       60

tgctccgacc aggacaacta ctgcgtgact gtgtctgcta gtgccggcat tgggaatctc      120

gtgacatttg gccacagcct gagcaagacc tgttccccgg cctgccccat cccagaaggc      180

gtcaatgttg gtgtggcttc catgggcatc agctgctgcc agagctttct gtgcaatttc      240

agt                                                                    243


<210>  3992
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  3992
aaggttcctg ttcccgacat ccggacgtgc cacttctgcc tcgtagaaga cccttctgta       60

ggatgcattt caggctcaga gaagtgtacc atcagcagct catccctgtg catggtgatc      120

accatctatt atgatgtcaa ggttcgcttc atcgttcgag gctgtggaca gtacatttcc      180

taccgctgcc aagaaaaacg caacacctac tttgcagagt actggtatca ggcccagtgc      240

tgtcagtacg attattgcaa ctcctggtca agcccccaac tccagagctc tctgccggag      300

ccccatgaca ggcccctggc cctgcctctg tctgactccc agattcagtg gttctaccag      360

gccctgaacc tctccctgcc cctccccaat ttccatgctg ggacggagcc tgatggcctg      420

gaccccatgg tcacactgtc cctgaacctg ggcttgtctt ttgctgagct gcgccgcatg      480

tacttgttcc tcaatagttc aggacttttg gttcttcccc aggctggact cttgacacct      540

cacccttcc                                                              549


<210>  3993
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  3993
aagtttgttc ctgtcaattg ggaaccccct caaccacttc cattccccaa atacctgcgc       60

tgctaccgat gcctcttgga gaccaaggag ttagggtgcc ttctgggatc tgacatctgc      120

ctcaccccag ctggcagcag ctgcatcact ctccacaaaa agaacagcag cggttctgac      180

gtcatggtga gtgactgccg aagtaaggag cagatgagtg attgttcaaa tacccgaact      240

tctccggtgt ctggcttctg gatattctct caatactgct tcctggattt ctgcaatgac      300

cctcaaaaca gagggctcta tactcct                                          327


<210>  3994
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  3994
gacattcgct gtcactcctg ctacaaggtc cctgtgctgg gctgtgtgga ccggcagtcc       60

tgccgcctgg agccaggaca gcaatgcctg acaacacatg cataccttgg taagatgtgg      120

gttttctcca atctgcgctg tggcacacca gaagagccct gtcaggaggc cttcaaccaa      180

accaaccgta agctgggtct gacatataac accacctgct gcaacaagga caactgcaac      240

agc                                                                    243


<210>  3995
<211>  255
<212>  DNA
<213>  Homo Sapiens

<400>  3995
aaccgaatgc ggtgctacaa ctgtggtgga agccccagca gttcttgcaa agaggccgtg       60

accacctgtg gcgagggcag accccagcca ggcctggaac agatcaagct acctggaaac      120

cccccagtga ccttgattca ccaacatcca gcctgcgtcg cagcccatca ttgcaatcaa      180

gtggagacag agtcggtggg agacgtgact tatccagccc acagggactg ctacctggga      240

gacctgtgca acagc                                                       255


<210>  3996
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  3996
gcagacaaca tgcaggccat ctatgtggcc ttgggggagg cagtagagct gccatgtccc       60

tcaccaccta ctctacatgg ggacgaacac ctgtcatggt tctgcagccc tgcagcaggc      120

tccttcacca ccctggtagc ccaagtccaa gtgggcaggc cagccccaga ccctggaaaa      180

ccaggaaggg aatccaggct cagactgctg gggaactatt ctttgtggtt ggagggatcc      240

aaagaggaag atgccgggcg gtactggtgc gctgtgctag gtcagcacca caactaccag      300

aactggaggg tgtacgacgt cttggtgctc aaaggatccc agttatctgc aagggctgca      360

gatggatccc cctgcaatgt cctcctgtgc tctgtggtcc ccagcagacg catggactct      420

gtgacctggc aggaagggaa gggtcccgtg aggggccgtg ttcagtcctt ctggggcagt      480

gaggctgccc tgctcttggt gtgtcctggg gaggggcttt ctgagcccag gagccgaaga      540

ccaagaatca tccgctgcct catgactcac aacaaagggg tcagctttag cctggcagcc      600

tccatcgatg cttctcctgc cctctgtgcc ccttccacgg gctgggacat gccttgg         657


<210>  3997
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  3997
ctgtggtgcc aggactgcac cctgaccacc aactccagcc attgcacccc aaagcagtgc       60

cagccgtccg acaccgtgtg tgccagtgtc cgaatcaccg atcccagcag cagcaggaag      120

gatcactcgg tgaacaagat gtgtgcctcc tcctgcgact tcgttaagcg acactttttc      180

tcagactatc tgatggggtt tattaactct gggatcttaa aggtcgacgt ggactgctgc      240

gagaaggatt tgtgcaatgg ggcggcaggg                                       270


<210>  3998
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  3998
gacgccaacc tgactgcgag acaacgagat ccagaggact cccagcgaac ggacgagggt       60

gacaatagag tgtggtgtca tgtttgtgag agagaaaaca ctttcgagtg ccagaaccca      120

aggaggtgca aatggacaga gccatactgc gttatagcgg ccgtgaaaat atttccacgt      180

tttttcatgg ttgcgaagca gtgctccgct ggttgtgcag cgatggagag acccaagcca      240

gaggagaagc ggtttctcct ggaagagccc atgcccttct tttacctcaa gtgttgtaaa      300

attcgctact gcaatttaga ggggccacct atcaactcat cagtgttcaa agaatatgct      360

ggg                                                                    363


<210>  3999
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  3999
tcagcagggt gtgcgactac cccggctagg aatttgtcat gttaccagtg ttttaaggtc       60

tcaagctgga cagaatgccc acctacgtgg tgcagtcccc tggaccaagt ttgtatctcc      120

aatgaagtag tggtatcatt caaatggagc gtaagggtgt tgctttcaaa aaggtgtgct      180

ccgagatgtc ctaacgacaa tatgaagttt gagtggtcac ctgctccgat ggttcagggg      240

gtgattacaa gaagatgttg cagttgggca ctgtgcaata gggcattaac tccacaggaa      300

ggg                                                                    303


<210>  4000
<211>  798
<212>  DNA
<213>  Homo Sapiens

<400>  4000
tatgaagatg gtatttacag tgttattcaa aaaaaggtaa catggtatga agcattaaac       60

atgtgttctc aaagtggagg tcacttggca agcgttcaca accaaaatgg ccagctcttt      120

ctggaagata ttgtaaaacg tgatggattt ccactatggg ttgggctctc aagtcatgat      180

ggaagtgaat caagttttga atggtctgat ggtagtacat ttgactatat cccatggaaa      240

ggccaaacat ctcctggaaa ttgtgttctc ttggatccaa aaggaacttg gaaacatgaa      300

aaatgcaact ctgttaagga tggtgctatt tgttataaac ctacaaaatc taaaaagctg      360

tcccgtctta catattcatc aagatgtcca gcagcaaaag agaatgggtc acggtggatc      420

cagtacaagg gtcactgtta caagtctgat caggcattgc acagtttttc agaggccaaa      480

aaattgtgtt caaaacatga tcactctgca actatcgttt ccataaaaga tgaagatgag      540

aataaatttg tgagcagact gatgagggaa aataataaca ttaccatgag agtttggctt      600

ggattatctc aacattctgt tgaccagtct tggagttggt tagatggatc agaagtgaca      660

tttgtcaaat gggaaaataa aagtaagagt ggtgttggaa gatgtagcat gttgatagct      720

tcaaatgaaa cttggaaaaa agttgaatgt gaacatggtt ttggaagagt tgtctgcaaa      780

gtgcctctgg gccctgat                                                    798


<210>  4001
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  4001
gtcaccatga agtctgtgaa ggtgtctgag aacttctcct gtaacatcac tctaatgtgc       60

tccgtgaagg gggcagagaa aagtgttctg tacagctgga ccccaaggga accccatgct      120

tctgagtcca atggaggctc cattcttacc gtctcccgaa caccatgtga cccagacctg      180

ccatacatct gcacagccca gaaccccgtc agccagagaa gctccctccc tgtccatgtt      240

gggcagttct gtacagatcc aggagcctcc agaggaggaa caacggggga gactgtggta      300

ggggtcctgg gagagccagt caccctgcca cttgcactcc cagcctgccg ggacacagag      360

aaggttgtct ggttgtttaa cacatccatc attagcaaag agagggaaga agcagcaacg      420

gcagatccac tcattaaatc cagggatcct tacaagaaca gggtgtgggt ctccagccag      480

gactgctccc tgaagatcag ccagctgaag atagaggacg ccggccccta ccatgcctac      540

gtgtgctcag aggcctccag cgtcaccagc atgacacatg tcaccctgct catctaccga      600

cctgagagaa acacaaag                                                    618


<210>  4002
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  4002
ctggactgtc acgtctgcgc ctataatgga gacaactgct ttaatccgat gagatgcccc       60

gcgatggtag catattgcat gactacaaga acaagtgccg cagaagcaat ctggtgtcac      120

cagtgtacgg gatttggcgg ctgctcccac gggagcaggt gccttagaga tagcactcac      180

tgcgtaacta cggcgactcg tgtcttgagt aatacagagg atcttcctct ggttactaag      240

atgtgccaca tcggatgtcc agatataccg tctcttggtc ttggccctta tgtgtcaatc      300

gcctgttgcc agacatcctt gtgtaaccat gat                                   333


<210>  4003
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4003
ctgcaaatcc agtgctacca gtgtgaagaa ttccagctga acaacgactg ctcctccccc       60

gagttcattg tgaattgcac ggtgaacgtt caagacatgt gtcagaaaga agtgatggag      120

caaagtgccg ggatcatgta ccgcaagtcc tgtgcatcat cagcggcctg tctcatcgcc      180

tctgccgggt accagtcctt ctgctcccca gggaaactga actcagtttg catcagctgc      240

tgcaacaccc ctctttgtaa cgggccaagg cccaagaaaa ggggaagttc t               291


<210>  4004
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  4004
ctgcgctgct acgtctgtcc ggagcccaca ggagtgtcgg actgtgtcac catcgccacc       60

tgcaccacca acgaaaccat gtgcaagacc acactctact cccgggagat agtgtacccc      120

ttccaggggg actccacggt gaccaagtcc tgtgccagca agtgtaagcc ctcggatgtg      180

gatggcatcg gccagaccct gcccgtgtcc tgctgcaata ctgagctgtg caatgtagac      240

ggg                                                                    243


<210>  4005
<211>  888
<212>  DNA
<213>  Homo Sapiens

<400>  4005
ctggagtgct acagctgcgt gcagaaagca gatgacggat gctccccgaa caagatgaag       60

acagtgaagt gcgcgccggg cgtggacgtc tgcaccgagg ccgtgggggc ggtggagacc      120

atccacggac aattctcgct ggcagtgcgg ggttgcggtt cgggactccc cggcaagaat      180

gaccgcggcc tggatcttca cgggcttctg gcgttcatcc agctgcagca atgcgctcag      240

gatcgctgca acgccaagct caacctcacc tcgcgggcgc tcgacccggc aggtaatgag      300

agtgcatacc cgcccaacgg cgtggagtgc tacagctgtg tgggcctgag ccgggaggcg      360

tgccagggta catcgccgcc ggtcgtgagc tgctacaacg ccagcgatca tgtctacaag      420

ggctgcttcg acggcaacgt caccttgacg gcagctaatg tgactgtgtc cttgcctgtc      480

cggggctgtg tccaggatga attctgcact cgggatggag taacaggccc agggttcacg      540

ctcagtggct cctgttgcca ggggtcccgc tgtaactctg acctccgcaa caagacctac      600

ttctcccctc gaatcccacc ccttgtccgg ctgccccctc cagagcccac gactgtggcc      660

tcaaccacat ctgtcaccac ttctacctcg gccccagtga gacccacatc caccaccaaa      720

cccatgccag cgccaaccag tcagactccg agacagggag tagaacacga ggcctcccgg      780

gatgaggagc ccaggttgac tggaggcgcc gctggccacc aggaccgcag caattcaggg      840

cagtatcctg caaaaggggg gccccagcag ccccataata aaggctgt                   888


<210>  4006
<211>  510
<212>  DNA
<213>  Homo Sapiens

<400>  4006
ctgcctcgta tgtcctgtgg ggctggatgc tataagaccc agaaagggac tgcaagggga       60

gtcgtgggct ttaaaggctg cagctcgtct tcgtcttacc ctgcgcaaat ctcctacctt      120

gtttccccac ccggagtgtc cattgcctcc tacagtcgcg tctgccggtc ttatctctgc      180

aacaacctca ccaatttgga gccttttgtg aaactcaagg ccagcactcc taagtctatc      240

acatctgcgt cctgtagctg cccgacctgt gtgggcgagc acatgaagga ttgcctccca      300

aattttgtca ccactaattc ttgccccttg gctgcttcta cgtgttacag ttccacctta      360

aaatttcagg cagggtttct caataccacc ttcctcctca tggggtgtgc tcgtgaacat      420

aaccagcttt tagcagattt tcatcatatt gggagcatca aagtgactga ggtcctcaac      480

atcttagaga agtctcagat tgttggtgca                                       510


<210>  4007
<211>  600
<212>  DNA
<213>  Homo Sapiens

<400>  4007
ctgcagtgct acagctttga gcacacctac tttggcccct ttgacctcag ggccatgaag       60

ctgcccagca tctcctgtcc tcatgagtgc tttgaggcta tcctgtctct ggacaccggg      120

tatcgcgcgc cggtgaccct ggtgcggaag ggctgctgga ccgggcctcc tgcgggccag      180

acgcaatcga acgcggacgc gctgccgcca gactactcgg tggtgcgcgg ctgcacaact      240

gacaaatgca acgcccacct catgactcat gacgccctcc ccaacctgag ccaagcaccc      300

gacccgccga cgctcagcgg cgccgagtgc tacgcctgta tcggggtcca ccaggatgac      360

tgcgctatcg gcaggtcccg acgagtccag tgtcaccagg accagaccgc ctgcttccag      420

ggcaatggca gaatgacagt tggcaatttc tcagtccctg tgtacatcag aacctgccac      480

cggccctcct gcaccaccga gggcagcacc agcccctgga cagccatcga cctccagggc      540

tcctgctgtg aggggtacct ctgcaacagg aaatccatga cccagccctt caccagtgct      600


<210>  4008
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  4008
gctcagtccc gagacttcac agtgaaagac attatctacc tccatccttc aaccacacca       60

tatcctggtg gatttaaatg tttcacctgt gaaaaggcag cagacaatta tgagtgcaac      120

cgatgggctc cagacatcta ctgccctcga gagaccagat actgctacac tcagcacaca      180

atggaagtca caggaaacag tatctcagtc accaaacgct gtgtcccact ggaagagtgc      240

ttatccactg gctgcagaga ctccgagcat gaaggccaca aggtctgcac ttcttgttgt      300

gaaggaaata tctgtaactt gccactgccc cgaaatgaaa ctgatgccac atttgccacg      360

acgtcaccta taaatcagac aaat                                             384


<210>  4009
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  4009
aagaacatca acttctataa tgtgaggcct cctctcgacc ctacaccatt tccaaatagc       60

ttcaagtgct ttacttgtga aaacgcaggg gataattata actgcaatcg atgggcagaa      120

gacaaatggt gtccacaaaa tacacagtac tgtttgacag ttcatcactt caccagccac      180

ggaagaagca catccatcac caaaaagtgt gcctccagaa gtgaatgtca ttttgtcggt      240

tgccaccaca gccgagattc tgaacatacg gagtgtaggt cttgctgtga aggaatgatc      300

tgcaatgtag aattacccac caatcacact aatgcagtgt ttgccgtaat gcacgctcag      360

agaacatctg gcagc                                                       375


<210>  4010
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  4010
cttagctgtg tgcagtgcaa ctcctgggag aagtcttgcg taaattcaat agcatccgaa       60

tgcccttccc atgcaaacac tagttgtatt agctcatccg cctcctcttc tttagagacg      120

cccgtgagac tttaccaaaa catgttctgc tccgctgaaa attgttccga agagacccat      180

ataacggcat tcacggtaca cgtttcagct gaagaacact tccacttcgt tagtcaatgt      240

tgccagggga aggaatgctc taacacctct gacgcacttg atcctcccct aaagaacgtc      300

tcctccaatg ccgaatgtcc tgcctgctat gaaagtaatg gaacaagctg ccacggtaaa      360

ccttggaagt gttatgagga ggagcaatgc gtcttcctgg tggccgagct taaaaatgat      420

attgaatcta aaagtctggt gttaaaggga tgcagcaatg taagcaacgc gacgtgtcag      480

ttcctgtccg gggaaaacaa gacactgggc ggtgtaattt tccgtaaatt tgaatgcgca      540

aacgtcaaca gcttgacacc aacttctgcc ccgacgacga gccataat                   588


<210>  4011
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  4011
cagtccctcc aggtgaagcc cctgcaggtg gagcccccgg agccggtggt ggccgtggcc       60

ttgggcgcct cgcgccagct cacctgccgc ctggcctgcg cggaccgcgg ggcctcggtg      120

cagtggcggg gcctggacac cagcctgggc gcggtgcagt cggacacggg ccgcagcgtc      180

ctcaccgtgc gcaacgcctc gctgtcggcg gccgggaccc gcgtgtgcgt gggctcctgc      240

gggggccgca ccttccagca caccgtgcag ctccttgtgt acgccttccc ggaccagctg      300

accgtctccc cagcagccct ggtgcctggt gacccggagg tggcctgtac ggcccacaaa      360

gtcacgcccg tggaccccaa cgcgctctcc ttctccctgc tcgtcggggg ccaggaactg      420

gagggggcgc aagccctggg cccggaggtg caggaggagg aggaggagcc ccagggggac      480

gaggacgtgc tgttcagggt gacagagcgc tggcggctgc cgcccctggg gacccctgtc      540

ccgcccgccc tctactgcca ggccacgatg aggctgcctg gcttggagct cagccaccgc      600

caggccatcc ccgtcctgca cagcccgacc tccccggagc ctcccgacac cacctccccg      660

gagcctccca acaccacctc cccggagtct cccgacacca cctccccgga gtctcccgac      720

accacctccc aggagcctcc cgacaccacc tcccaggagc ctcccgacac cacctcccag      780

gagcctcccg acaccacctc cccggagcct cccgacaaga cctccccgga gcccgccccc      840

cagcagggct ccacacacac ccccaggagc ccaggctcca ccaggactcg ccgccctgag      900

atctcccagg ctgggcccac gcagggagaa gtgatcccaa caggctcgtc caaacctgcg      960

ggtgaccag                                                              969


<210>  4012
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  4012
ggtcactggg gtgcctggat gccctcgtcc atctcggcct tcgaaggcac gtgcgtctcc       60

atcccctgcc gctttgactt cccggatgag ctgcggcccg ctgtggtgca tggtgtctgg      120

tacttcaata gcccctaccc caagaactac cccccggtgg tcttcaagtc gcgcacccaa      180

gtagtccacg agagcttcca gggccgcagc cgcctcctgg gggacctggg cctgcgaaac      240

tgcaccctcc tgctcagcaa cgtcagcccc gagctgggcg ggaagtacta cttccgtggg      300

gacctgggcg gctacaacca gtacaccttc tcagagcaca gtgtcctgga tatcgtcaac      360

acccccaaca tcgtggtgcc cccagaggtg gtggcaggca cggaggtgga ggtcagctgc      420

atggtgccgg acaactgccc agagctgcgc cctgagctga gctggctggg ccacgagggg      480

ctgggggagc ccgctgtgct gggccggctg cgggaggacg agggcacctg ggtgcaggtg      540

tcactgctgc acttcgtgcc cacgagggag gccaacggcc acaggctggg ctgccaggcc      600

tccttcccca acaccaccct gcagttcgag ggctacgcca gcatggacgt caagtacccc      660

ccggtgattg tggagatgaa ctcctcggtg gaggccatcg agggctccca cgtgagcctg      720

ctctgtgggg ctgacagcaa ccccccgccg ctgctgacct ggatgcggga cgggacagtc      780

ctccgggagg cggtggccga gagcctgctc ctggagctgg aggaggtgac ccccgccgaa      840

gacggcgtct atgcctgcct ggccgagaat gcctatggcc aggacaaccg caccgtgggg      900

ctcagtgtca tgtatgcacc ctggaagcca acagtgaacg ggacaatggt ggccgtagag      960

ggggagacgg tctctatctt gtgctccaca cagagcaacc cggaccctat tctcaccatc     1020

ttcaaggaga agcagatcct gtccacggtc atctacgaga gcgagctgca gctggagctg     1080

ccggccgtgt cacccgagga tgatggagag tactggtgtg tggctgagaa ccagtatggc     1140

cagagggcca ctgccttcaa cctgtctgtg gagttcgccc ctgtgctcct cctggagtcc     1200

cactgcgcgg cagcccgaga cacggtgcag tgcctgtgcg tggtgaagtc caacccggag     1260

ccgtccgtgg cctttgagct gccatcgcgc aatgtgaccg tgaacgagag cgagcgggag     1320

ttcgtgtact cggagcgcag cggcctcgtg ctcaccagca tcctcacgct gcgggggcag     1380

gcccaggccc cgccccgcgt catctgcacc gcgaggaacc tctatggcgc caagagcctg     1440

gagctgccct tccagggagc ccatcgactg atgtgggcca agatcgggcc t              1491


<210>  4013
<211>  2586
<212>  DNA
<213>  Homo Sapiens

<400>  4013
gccgcggagc tcagttacag cttgcgtggc aactggagca tctgcaatgg gaacggctcg       60

ctggagctgc ccggggcggt ccctggctgc gtgcacagcg ccttgttcca gcagggcctg      120

atccaggatt cttactacag atttaatgac cttaactaca gatgggtctc tttggataac      180

tggacctata gcaaagaatt taaaatcccc tttgaaatta gcaaatggca aaaagtaaat      240

ttgattcttg agggagtgga tacggtttca aaaatcctgt tcaatgaagt cactattggg      300

gaaacagaca atatgttcaa tagatatagc tttgatatta ccaacgtggt cagggacgtg      360

aactccattg agctgcgttt ccagtcagcg gtgttgtatg cagcacagca gagcaaagct      420

cacactcgct accaggttcc cccagactgc cctccacttg tgcagaaggg tgaatgccat      480

gtcaactttg ttcggaagga gcaatgttcc tttagttggg actgggggcc ttcctttcct      540

acccagggaa tctggaaaga tgttagaatt gaagcctata atatttgtca cctgaactac      600

ttcacatttt ccccaatata tgataagagt gcccaggagt ggaatctgga aatagagtct      660

acatttgatg ttgtcagctc aaagccagtt ggtggtcaag tgatcgtagc catccctaag      720

ttgcaaacac aacagacata cagcattgaa cttcaacctg ggaaaaggat tgttgagcta      780

tttgtgaaca ttagcaagaa tattactgta gaaacttggt ggcctcatgg acatggaaac      840

cagactgggt acaacatgac tgttcttttt gaactggatg gaggcttaaa tattgaaaaa      900

tcagctaagg tttattttag gacagtggaa cttatagaag agcctataaa agggtctcct      960

ggtttgagtt tctatttcaa aattaatgga tttcccatat ttctaaaagg ctcaaactgg     1020

atcccagcag attcattcca ggaccgagta acctctgagt tgttacggct ccttttacag     1080

tctgttgtgg atgctaatat gaatactctt cgggtttggg gaggaggaat ttatgagcag     1140

gatgaattct atgaactctg tgatgaacta ggaataatgg tatggcagga ttttatgttt     1200

gcctgtgccc tttatccaac tgatcagggc ttcctggatt cagtgacagc agaagttgcc     1260

taccagatca agagactgaa atctcatcct tctatcatca tatggagtgg caataatgaa     1320

aatgaggagg cgctgatgat gaattggtat catatcagtt tcactgaccg gccaatctac     1380

atcaaggact atgtgacact ctatgtgaaa aacatcagag agctcgtact ggcaggagac     1440

aagagtcgtc cttttattac gtccagtcct acaaatgggg ctgaaactgt tgcagaagcc     1500

tgggtctctc aaaaccctaa tagcaattat tttggtgatg tacattttta tgactatatc     1560

agtgattgct ggaactggaa agttttccca aaagctcgat ttgcatctga atatggatat     1620

cagtcctggc cgtccttcag tacattagaa aaggtctcgt ctacagagga ctggtctttc     1680

aatagcaagt tttcacttca tcgacaacat cacgaaggtg gtaacaaaca aatgctttat     1740

caggctggac ttcatttcaa actcccccaa agcacagatc cattacgcac atttaaagat     1800

accatctacc ttactcaggt gatgcaggcc cagtgtgtca aaacagaaac tgaattctac     1860

cgccgtagtc gcagcgagat agtggatcag caagggcaca cgatgggggc actttattgg     1920

cagttgaatg acatctggca agctccttcc tgggcttctc ttgagtacgg aggaaagtgg     1980

aaaatgcttc attactttgc tcagaatttc tttgctccac tgttgccagt aggctttgag     2040

aatgaaaaca tgttctatat ctatggtgtg tcagatcttc actcggatta ttcgatgaca     2100

ctcagtgtga gagtccatac atggagctcc ctggagcccg tgtgctctcg tgtgactgaa     2160

cgttttgtga tgaaaggagg agaggctgtc tgcctttatg aggagccagt gtctgaattg     2220

ctgaggagat gtgggaattg cacacgggaa agctgtgtgg tttcctttta cctttcagct     2280

gaccatgaac tcctgagccc gaccaactac cacttcctgt cctcaccgaa ggaggccgtg     2340

gggctctgca aggcgcagat cactgccatc atctctcagc aaggtgacat atttgttttt     2400

gacctggaga cctcagctgt cgctcccttt gtttggttgg atgtaggaag catcccaggg     2460

agatttagtg acaatggttt cctcatgact gagaagacac gaactatatt attttaccct     2520

tgggagccca ccagcaagaa tgagttggag caatcttttc atgtgacctc cttaacagat     2580

atttac                                                                2586


<210>  4014
<211>  2127
<212>  DNA
<213>  Homo Sapiens

<400>  4014
cacaccgtgg agctaaacaa tatgtttggc cagatccagt cgcctggtta tccagactcc       60

tatcccagtg attcagaggt gacttggaat atcactgtcc cagatgggtt tcggatcaag      120

ctttacttca tgcacttcaa cttggaatcc tcctaccttt gtgaatatga ctatgtgaag      180

gtagaaactg aggaccaggt gctggcaacc ttctgtggca gggagaccac agacacagag      240

cagactcccg gccaggaggt ggtcctctcc cctggctcct tcatgtccat cactttccgg      300

tcagatttct ccaatgagga gcgtttcaca ggctttgatg cccactacat ggctgtggat      360

gtggacgagt gcaaggagag ggaggacgag gagctgtcct gtgaccacta ctgccacaac      420

tacattggcg gctactactg ctcctgccgc ttcggctaca tcctccacac agacaacagg      480

acctgccgag tggagtgcag tgacaacctc ttcactcaaa ggactggggt gatcaccagc      540

cctgacttcc caaaccctta ccccaagagc tctgaatgcc tgtataccat cgagctggag      600

gagggtttca tggtcaacct gcagtttgag gacatatttg acattgagga ccatcctgag      660

gtgccctgcc cctatgacta catcaagatc aaagttggtc caaaagtttt ggggcctttc      720

tgtggagaga aagccccaga acccatcagc acccagagcc acagtgtcct gatcctgttc      780

catagtgaca actcgggaga gaaccggggc tggaggctct catacagggc tgcaggaaat      840

gagtgcccag agctacagcc tcctgtccat gggaaaatcg agccctccca agccaagtat      900

ttcttcaaag accaagtgct cgtcagctgt gacacaggct acaaagtgct gaaggataat      960

gtggagatgg acacattcca gattgagtgt ctgaaggatg ggacgtggag taacaagatt     1020

cccacctgta aaattgtaga ctgtagagcc ccaggagagc tggaacacgg gctgatcacc     1080

ttctctacaa ggaacaacct caccacatac aagtctgaga tcaaatactc ctgtcaggag     1140

ccctattaca agatgctcaa caataacaca ggtatatata cctgttctgc ccaaggagtc     1200

tggatgaata aagtattggg gagaagccta cccacctgcc ttccagagtg tggtcagccc     1260

tcccgctccc tgccaagcct ggtcaagagg atcattgggg gccgaaatgc tgagcccggc     1320

ctcttcccgt ggcaggccct gatagtggtg gaggacactt cgagagtgcc aaatgacaag     1380

tggtttggga gtggggccct gctctctgcg tcctggatcc tcacagcagc tcatgtgctg     1440

cgctcccagc gtagagacac cacggtgata ccagtctcca aggagcatgt caccgtctac     1500

ctgggcttgc atgatgtgcg agacaaatcg ggggcagtca acagctcagc tgcccgagtg     1560

gtgctccacc cagacttcaa catccaaaac tacaaccacg atatagctct ggtgcagctg     1620

caggagcctg tgcccctggg accccacgtt atgcctgtct gcctgccaag gcttgagcct     1680

gaaggcccgg ccccccacat gctgggcctg gtggccggct ggggcatctc caatcccaat     1740

gtgacagtgg atgagatcat cagcagtggc acacggacct tgtcagatgt cctacagtat     1800

gtcaagttac ccgtggtgcc tcacgctgag tgcaaaacta gctatgagtc ccgctcgggc     1860

aattacagcg tcacggagaa catgttctgt gctggctact acgagggcgg caaagacacg     1920

tgccttggag atagcggtgg ggcctttgtc atctttgatg acttgagcca gcgctgggtg     1980

gtgcaaggcc tggtgtcctg ggggggacct gaagaatgcg gcagcaagca ggtctatgga     2040

gtctacacaa aggtctccaa ttacgtggac tgggtgtggg agcagatggg cttaccacaa     2100

agtgttgtgg agccccaggt ggaacgg                                         2127


<210>  4015
<211>  1422
<212>  DNA
<213>  Homo Sapiens

<400>  4015
agtccagggt tggctccaca aagccgtgga catctatgca gaactagacc gacggactta       60

gttttcgttg tagattcttc tagaagcgtt aggccggttg agttcgaaaa ggtgaaagtc      120

ttcctttccc aagttatcga gagcttggac gtcggcccca acgcaacgcg tgttggtatg      180

gttaattacg ccagcacagt caaacaagag ttttctctta gagcccatgt ctctaaggct      240

gccttgctgc aagcggttag aaggattcag cctctaagta caggaaccat gacgggacta      300

gccattcagt ttgcaataac gaaagcgttt ggagacgcag agggagggag aagccgtagc      360

ccagacattt caaaagtggt cattgtggtg acagatggca gaccccaaga cagtgtacaa      420

gatgtgagtg ctagggccag agcctctgga gtagagttgt ttgcaatcgg tgttgggtcc      480

gtggacaaag ctacgttgag acaaattgcg tcagaaccac aagacgaaca tgtggactac      540

gtggagtctt attcagtcat tgaaaagctg tctaggaagt ttcaagaagc cttctgtgtc      600

gtcagtgatt tgtgtgcaac gggcgaccat gactgtgaac aagtatgtat aagcagccct      660

gggagttaca catgcgcgtg ccacgaaggt ttcaccctta attccgatgg aaaaacttgc      720

aacgtatgct ccggaggggg tggctcctca gcgaccgacc tggtattctt gatcgatgga      780

agtaagtccg tcaggccgga gaacttcgag ctggtcaaga agttcatttc tcaaattgtg      840

gacacgctag acgttagcga caagctggcg caggtcgggc ttgtccagta ttcatcttcc      900

gtcagacaag agtttccctt gggcagattt cacacgaaga aagacatcaa agcggctgtc      960

cgtaacatga gttacatgga gaagggcacg atgacgggtg ccgccctaaa gtacctaatc     1020

gacaattcct ttacagtttc cagtggtgcc agacctggtg cccaaaaggt tggaattgta     1080

tttactgatg gtaggagtca ggattacatt aacgacgcag ccaagaaggc taaggatcta     1140

ggtttcaaga tgttcgcagt gggcgtcggt aatgcagtcg aggacgagtt gagagagatc     1200

gcatcagaac cggtggcaga acactacttc tataccgcgg acttcaaaac aattaaccaa     1260

atcggaaaga agctgcaaaa gaaaatctgt gtagaggagg acccttgcgc ctgtgaatca     1320

ttagtcaagt tccaggccaa agtagaagga ttactgcagg ccctgacgag gaagctggaa     1380

gcggtaagta agagactagc gattttagag aacacagtgg tt                        1422


<210>  4016
<211>  2742
<212>  DNA
<213>  Homo Sapiens

<400>  4016
agggagcggt cacgtgggag gtccatctct aggggcagac acgctcggac ccacccgcag       60

acggcccttc tggagagttc ctgtgagaac aagcgggcag acctggtttt catcattgac      120

agctctcgca gtgtcaacac ccatgactat gcaaaggtca aggagttcat cgtggacatc      180

ttgcaattct tggacattgg tcctgatgtc acccgagtgg gcctgctcca atatggcagc      240

actgtcaaga atgagttctc cctcaagacc ttcaagagga agtccgaggt ggagcgtgct      300

gtcaagagga tgcggcatct gtccacgggc accatgaccg ggctggccat ccagtatgcc      360

ctgaacatcg cattctcaga agcagagggg gcccggcccc tgagggagaa tgtgccacgg      420

gtcataatga tcgtgacaga tgggagacct caggactccg tggccgaggt ggctgctaag      480

gcacgggaca cgggcatcct aatctttgcc attggtgtgg gccaggtaga cttcaacacc      540

ttgaagtcca ttgggagtga gccccatgag gaccatgtct tccttgtggc caatttcagc      600

cagattgaga cgctgacctc cgtgttccag aagaagttgt gcacggccca catgtgcagc      660

accctggagc ataactgtgc ccacttctgc atcaacatcc ctggctcata cgtctgcagg      720

tgcaaacaag gctacattct caactcggat cagacgactt gcagaatcca ggatctgtgt      780

gccatggagg accacaactg tgagcagctc tgtgtgaatg tgccgggctc cttcgtctgc      840

cagtgctaca gtggctacgc cctggctgag gatgggaaga ggtgtgtggc tgtggactac      900

tgtgcctcag aaaaccacgg atgtgaacat gagtgtgtaa atgctgatgg ctcctacctt      960

tgccagtgcc atgaaggatt tgctcttaac ccagatgaaa aaacgtgcac aaagatagac     1020

tactgtgcct catctaatca tggatgtcag catgagtgtg ttaacacaga tgattcctat     1080

tcctgccact gcctgaaagg ctttaccctg aatccagata agaaaacctg cagaaggatc     1140

aactactgtg cactgaacaa accgggctgt gagcatgagt gcgtcaacat ggaggagagc     1200

tactactgcc gctgccaccg tggctacact ctggacccca atggcaaaac ctgcagccga     1260

gtggaccact gtgcacagca ggaccatggc tgtgagcagc tgtgtctgaa cacggaggat     1320

tccttcgtct gccagtgctc agaaggcttc ctcatcaacg aggacctcaa gacctgctcc     1380

cgggtggatt actgcctgct gagtgaccat ggttgtgaat actcctgtgt caacatggac     1440

agatcctttg cctgtcagtg tcctgaggga cacgtgctcc gcagcgatgg gaagacgtgt     1500

gcaaaattgg actcttgtgc tctgggggac cacggttgtg aacattcgtg tgtaagcagt     1560

gaagattcgt ttgtgtgcca gtgctttgaa ggttatatac tccgtgaaga tggaaaaacc     1620

tgcagaagga aagatgtctg ccaagctata gaccatggct gtgaacacat ttgtgtgaac     1680

agtgacgact catacacgtg cgagtgcttg gagggattcc ggctcgctga ggatgggaaa     1740

cgctgccgaa ggaaggatgt ctgcaaatca acccaccatg gctgcgaaca catttgtgtt     1800

aataatggga attcctacat ctgcaaatgc tcagagggat ttgttctagc tgaggacgga     1860

agacggtgca agaaatgcac tgaaggccca attgacctgg tctttgtgat cgatggatcc     1920

aagagtcttg gagaagagaa ttttgaggtc gtgaagcagt ttgtcactgg aattatagat     1980

tccttgacaa tttcccccaa agccgctcga gtggggctgc tccagtattc cacacaggtc     2040

cacacagagt tcaccctgag aaacttcaac tcagccaaag acatgaaaaa agccgtggcc     2100

cacatgaaat acatgggaaa gggctctatg actgggctgg ccctgaaaca catgtttgag     2160

agaagtttta cccaaggaga aggggccagg cccctttcca caagggtgcc cagagcagcc     2220

attgtgttca ccgacggacg ggctcaggat gacgtctccg agtgggccag taaagccaag     2280

gccaatggta tcactatgta tgctgttggg gtaggaaaag ccattgagga ggaactacaa     2340

gagattgcct ctgagcccac aaacaagcat ctcttctatg ccgaagactt cagcacaatg     2400

gatgagataa gtgaaaaact caagaaaggc atctgtgaag ctctagaaga ctccgatgga     2460

agacaggact ctccagcagg ggaactgcca aaaacggtcc aacagccaac agtgcaacac     2520

agatatctgt ttgaagaaga caatctttta cggtctacac aaaagctttc ccattcaaca     2580

aaaccttcag gaagcccttt ggaagaaaaa cacgatcaat gcaaatgtga aaaccttata     2640

atgttccaga accttgcaaa cgaagaagta agaaaattaa cacagcgctt agaagaaatg     2700

acacagagaa tggaagccct ggaaaatcgc ctgagataca ga                        2742


<210>  4017
<211>  1374
<212>  DNA
<213>  Homo Sapiens

<400>  4017
gaccccgtgg cccgcccggg cttccggagg ctggagaccc gaggtcccgg gggcagccct       60

ggacgccgcc cctctcctgc ggctcccgac ggcgcgcccg cttccgggac cagcgagcct      120

ggccgcgccc gcggtgcagg tgtttgcaag agcagaccct tggacctggt gtttatcatt      180

gatagttctc gtagcgtacg gcccctggaa ttcaccaaag tgaaaacttt tgtctcccgg      240

ataatcgaca ctctggacat tgggccagcc gacacgcggg tggcagtggt gaactatgct      300

agcactgtga agatcgagtt ccaactccag gcctacacag ataagcagtc cctgaagcag      360

gccgtgggtc gaatcacacc cttgtcaaca ggcaccatgt caggcctagc catccagaca      420

gcaatggacg aagccttcac agtggaggca ggggctcgag agccctcttc taacatccct      480

aaggtggcca tcattgttac agatgggagg ccccaggacc aggtgaatga ggtggcggct      540

cgggcccaag catctggtat tgagctctat gctgtgggcg tggaccgggc agacatggcg      600

tccctcaaga tgatggccag tgagccccta gaggagcatg ttttctacgt ggagacctat      660

ggggtcattg agaaactttc ctctagattc caggaaacct tctgtgcgct ggacccctgt      720

gtgcttggaa cacaccagtg ccagcacgtc tgcatcagtg atggggaagg caagcaccac      780

tgtgagtgta gccaaggata caccttgaat gccgacaaga aaacgtgttc agctcttgat      840

aggtgtgctc ttaacaccca cggatgtgag cacatctgtg tgaatgacag aagtggctct      900

tatcattgtg agtgctatga aggttatacc ttgaatgaag acaggaaaac ttgttcagct      960

caagataaat gtgctttggg tacccatggg tgtcagcaca tttgtgtgaa tgacagaaca     1020

gggtcccatc attgtgaatg ctatgagggc tacactctga atgcagataa aaaaacatgt     1080

tcagtccgtg acaagtgtgc cctaggctct catggttgcc agcacatttg tgtgagtgat     1140

ggggccgcat cctaccactg tgattgctat cctggctaca ccttaaatga ggacaagaaa     1200

acatgttcag ccactgagga agcacgaaga cttgtttcca ctgaagatgc ttgtggatgt     1260

gaagctacac tggcattcca ggacaaggtc agctcgtatc ttcaaagact gaacactaaa     1320

cttgatgaca ttttggagaa gttgaaaata aatgaatatg gacaaataca tcgt           1374


<210>  4018
<211>  1689
<212>  DNA
<213>  Homo Sapiens

<400>  4018
acccagctcc agttgacagg tcccaggtgt cacactgggc ccctggatct ggtgttcgtg       60

attgacagct cccgcagcgt gcgccctttc gagttcgaga ccatgcggca gttcctcatg      120

ggcctcctcc gaggcctgaa cgtgggtccc aacgccacgc gcgttggcgt gatccagtat      180

tcgagtcaag tgcagagcgt cttccctctc cgcgcgttct ctcgccgcga ggacatggag      240

cgcgccatcc gcgacctggt gcctctggcg caaggcacca tgacgggact ggcgatccag      300

tacgccatga acgtggcctt cagtgtggcc gagggcgcgc gaccgccaga ggagcgcgtg      360

ccgcgtgtcg ctgtcatcgt gacagacggg cggccccagg accgcgtggc cgaggtggcg      420

gcacaggcgc gcgccagcgg cattgaaatt tacgcggtgg gggtgcagcg cgcggacgtg      480

ggctccctgc gcgccatggc atcgcccccg ctagacgagc acgtcttcct cgtagagtcc      540

ttcgacctca tccaggagtt cggcctgcag ttccagagcc ggctgtgtgc cattgatctg      600

tgtgctgaag ggacccatgg atgtgagcac cactgcgtca attccccagg ctcctatttc      660

tgtcactgcc aagttggctt tgtactccag caggaccaga ggagctgcag ggccattgac      720

tactgcagct ttgggaacca tagctgtcag catgagtgtg ttagcacccc tggtgggcca      780

cggtgccact gcagagaggg ccatgacttg cagcctgatg ggaggagctg tcaggtccgg      840

gacctttgca atggcgtgga ccatggctgt gagttccagt gtgtgagcga gggcctctcc      900

taccgctgcc tgtgccccga ggggcggcaa cttcaggcag atggcaagag ctgcaaccgg      960

tgccgggaag gccacgtgga ccttgttctg ctggttgatg gctccaagag cgtgcgtcca     1020

caaaacttcg agctagtgaa gcgcttcgtg aaccagattg tggacttcct agatgtgtcc     1080

cccgagggca cgcgggtggg gctggtgcag ttctcgagcc gcgtgcgcac cgagttccct     1140

ctgggtcgct acggcaccgc agccgaggtg aagcaggcgg tcctggccgt ggagtacatg     1200

gaacgcggca ccatgacagg gctggcgttg cggcacatgg tggagcacag cttctccgag     1260

gcgcagggtg cacggccccg tgcccttaac gtgcctcgtg ttggcctggt cttcacggat     1320

ggccgctccc aggatgacat ctcggtgtgg gcagcgcgcg ccaaggagga aggcatcgtc     1380

atgtacgccg tgggcgtggg caaggcggtg gaggcggagc tgcgcgagat cgcctcggag     1440

ccagcggaac tgcacgtgtc ctatgccccg gacttcggca ccatgacgca cctgctggag     1500

aacctcagag gcagcatctg tccagaggag ggcatcagcg cagggacaga gcttcggagc     1560

ccatgcgaat gcgaaagcct cgtggagttc cagggccgca cgctgggggc gctcgagagc     1620

ctgacgctga acctggccca gctgacggcg cgcctggagg atctggagaa ccagctggcc     1680

aaccagaag                                                             1689


<210>  4019
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  4019
gaaactgtga cctgtgagga tgcccaaaag acctgccctg cagtgattgc ctgtagctct       60

ccaggcatca acggcttccc aggcaaagat gggcgtgatg gcaccaaggg agaaaagggg      120

gaaccaggcc aagggctcag aggcttacag ggcccccctg gaaagttggg gcctccagga      180

aatccagggc cttctgggtc accaggacca aagggccaaa aaggagaccc tggaaaaagt      240

ccggatggtg atagtagcct ggctgcctca gaaagaaaag ctctgcaaac agaaatggca      300

cgtatcaaaa agtggctcac cttctctctg ggcaaacaag ttgggaacaa gttcttcctg      360

accaatggtg aaataatgac ctttgaaaaa gtgaaggcct tgtgtgtcaa gttccaggcc      420

tctgtggcca cccccaggaa tgctgcagag aatggagcca ttcagaatct catcaaggag      480

gaagccttcc tgggcatcac tgatgagaag acagaagggc agtttgtgga tctgacagga      540

aatagactga cctacacaaa ctggaacgag ggtgaaccca acaatgctgg ttctgatgaa      600

gattgtgtat tgctactgaa aaatggccag tggaatgacg tcccctgctc cacctcccat      660

ctggccgtct gtgagttccc tatc                                             684


<210>  4020
<211>  1608
<212>  DNA
<213>  Homo Sapiens

<400>  4020
gtgcccggag aggctgagca gcctgcgcct gagctggtgg aggtggaagt gggcagcaca       60

gcccttctga agtgcggcct ctcccagtcc caaggcaacc tcagccatgt cgactggttt      120

tctgtccaca aggagaagcg gacgctcatc ttccgtgtgc gccagggcca gggccagagc      180

gaacctgggg agtacgagca gcggctcagc ctccaggaca gaggggctac tctggccctg      240

actcaagtca ccccccaaga cgagcgcatc ttcttgtgcc agggcaagcg ccctcggtcc      300

caggagtacc gcatccagct ccgcgtctac aaagctccgg aggagccaaa catccaggtc      360

aaccccctgg gcatccctgt gaacagtaag gagcctgagg aggtcgctac ctgtgtaggg      420

aggaacgggt accccattcc tcaagtcatc tggtacaaga atggccggcc tctgaaggag      480

gagaagaacc gggtccacat tcagtcgtcc cagactgtgg agtcgagtgg tttgtacacc      540

ttgcagagta ttctgaaggc acagctggtt aaagaagaca aagatgccca gttttactgt      600

gagctcaact accggctgcc cagtgggaac cacatgaagg agtccaggga agtcaccgtc      660

cctgttttct acccgacaga aaaagtgtgg ctggaagtgg agcccgtggg aatgctgaag      720

gaaggggacc gcgtggaaat caggtgtttg gctgatggca accctccacc acacttcagc      780

atcagcaagc agaaccccag caccagggag gcagaggaag agacaaccaa cgacaacggg      840

gtcctggtgc tggagcctgc ccggaaggaa cacagtgggc gctatgaatg tcagggcctg      900

gacttggaca ccatgatatc gctgctgagt gaaccacagg aactactggt gaactatgtg      960

tctgacgtcc gagtgagtcc cgcagcccct gagagacagg aaggcagcag cctcaccctg     1020

acctgtgagg cagagagtag ccaggacctc gagttccagt ggctgagaga agagacaggc     1080

caggtgctgg aaagggggcc tgtgcttcag ttgcatgacc tgaaacggga ggcaggaggc     1140

ggctatcgct gcgtggcgtc tgtgcccagc atacccggcc tgaaccgcac acagctggtc     1200

aacgtggcca tttttggccc cccttggatg gcattcaagg agaggaaggt gtgggtgaaa     1260

gagaatatgg tgttgaatct gtcttgtgaa gcgtcagggc acccccggcc caccatctcc     1320

tggaacgtca acggcacggc aagtgaacaa gaccaagatc cacagcgagt cctgagcacc     1380

ctgaatgtcc tcgtgacccc ggagctgttg gagacaggtg ttgaatgcac ggcctccaac     1440

gacctgggca aaaacaccag catcctcttc ctggagctgg tcaatttaac caccctcaca     1500

ccagactcca acacaaccac tggcctcagc acttccactg ccagtcctca taccagagcc     1560

aacagcacct ccacagagag aaagctgccg gagccggaga gccggggc                  1608


<210>  4021
<211>  882
<212>  DNA
<213>  Homo Sapiens

<400>  4021
tgtgaggagc caccaacatt tgaagctatg gagctcattg gtaaaccaaa accctactat       60

gagattggtg aacgagtaga ttataagtgt aaaaaaggat acttctatat acctcctctt      120

gccacccata ctatttgtga tcggaatcat acatggctac ctgtctcaga tgacgcctgt      180

tatagagaaa catgtccata tatacgggat cctttaaatg gccaagcagt ccctgcaaat      240

gggacttacg agtttggtta tcagatgcac tttatttgta atgagggtta ttacttaatt      300

ggtgaagaaa ttctatattg tgaacttaaa ggatcagtag caatttggag cggtaagccc      360

ccaatatgtg aaaaggtttt gtgtacacca cctccaaaaa taaaaaatgg aaaacacacc      420

tttagtgaag tagaagtatt tgagtatctt gatgcagtaa cttatagttg tgatcctgca      480

cctggaccag atccattttc acttattgga gagagcacga tttattgtgg tgacaattca      540

gtgtggagtc gtgctgctcc agagtgtaaa gtggtcaaat gtcgatttcc agtagtcgaa      600

aatggaaaac agatatcagg atttggaaaa aaattttact acaaagcaac agttatgttt      660

gaatgcgata agggttttta cctcgatggc agcgacacaa ttgtctgtga cagtaacagt      720

acttgggatc ccccagttcc aaagtgtctt aaagtgtcga cttcttccac tacaaaatct      780

ccagcgtcca gtgcctcagg tcctaggcct acttacaagc ctccagtctc aaattatcca      840

ggatatccta aacctgagga aggaatactt gacagtttgg at                         882


<210>  4022
<211>  2742
<212>  DNA
<213>  Homo Sapiens

<400>  4022
caaggagtct acgctccagc ccaggcgcag atcgtgcatg cgggccaggc atgtgtggtg       60

aaagaggaca atatcagcga gcgtgtctac accatccggg agggggacac cctcatgctg      120

cagtgccttg taacagggca ccctcgaccc caggtacggt ggaccaagac ggcaggtagc      180

gcctcggaca agttccagga gacatcggtg ttcaacgaga cgctgcgcat cgagcgtatt      240

gcacgcacgc agggcggccg ctactactgc aaggctgaga acggcgtggg ggtgccggcc      300

atcaagtcca tccgcgtgga cgtgcagtac ctggatgagc caatgctgac ggtgcaccag      360

acggtgagcg atgtgcgagg caacttctac caggagaaga cggtgttcct gcgctgtact      420

gtcaactcca acccgcctgc ccgcttcatc tggaagcggg gttccgatac cctatcccac      480

agccaggaca atggggttga catctatgag cccctctaca ctcaggggga gaccaaggtc      540

ctgaagctga agaacctgcg gccccaggac tatgccagct acacctgcca ggtgtctgtg      600

cgtaacgtgt gcggcatccc agacaaggcc atcaccttcc ggctcaccaa caccacggca      660

ccaccagccc tgaagctgtc tgtgaacgaa actctggtgg tgaaccctgg ggagaatgtg      720

acggtgcagt gtctgctgac aggcggtgat cccctccccc agctgcagtg gtcccatggg      780

cctggcccac tgcccctggg tgctctggcc cagggtggca ccctcagcat cccttcagtg      840

caggcccggg actctggcta ctacaactgc acagccacca acaatgtggg caaccctgcc      900

aagaagactg tcaacctgct ggtgcgatcc atgaagaacg ctacattcca gatcactcct      960

gacgtgatca aagagagtga gaacatccag ctgggccagg acctgaagct atcgtgccac     1020

gtggatgcag tgccccagga gaaggtgacc taccagtggt tcaagaatgg caagccggca     1080

cgcatgtcca agcggctgct ggtgacccgc aatgatcctg agctgcccgc agtcaccagc     1140

agcctagagc tcattgacct gcacttcagt gactatggca cctacctgtg catggcttct     1200

ttcccagggg cacccgtgcc cgacctcagc gtcgaggtca acatctcctc tgagacagtg     1260

ccgcccacca tcagtgtgcc caagggtagg gccgtggtga ccgtgcgcga gggatcgcct     1320

gccgagctgc aatgcgaggt gcggggcaag ccgcggccgc cagtgctctg gtcccgcgtg     1380

gacaaggagg ctgcactgct gccctcgggg ctgcccctgg aggagactcc ggacgggaag     1440

ctgcggctgg agcgagtgag ccgagacatg agcgggacct accgctgcca gacggcccgc     1500

tataatggct tcaacgtgcg cccccgtgag gcccaggtgc agctgaacgt gcagttcccg     1560

ccggaggtgg agcccagttc ccaggacgtg cgccaggcgc tgggccggcc cgtgctcctg     1620

cgctgctcgc tgctgcgagg cagcccccag cgcatcgcct cggctgtgtg gcgtttcaaa     1680

gggcagctgc tgccgccgcc gcctgttgtt cccgccgccg ccgaggcgcc ggatcacgcg     1740

gagctgcgcc tcgacgccgt aactcgcgac agcagcggca gctacgagtg cagcgtctcc     1800

aacgatgtgg gctcggctgc ctgcctcttc caggtctccg ccaaagccta cagcccggag     1860

ttttacttcg acacccccaa ccccacccgc agccacaagc tgtccaagaa ctactcctac     1920

gtgctgcagt ggactcagag ggagcccgac gctgtcgacc ctgtgctcaa ctacagactc     1980

agcatccgcc agttgaacca gcacaatgcg gtggtcaagg ccatcccggt ccggcgtgtg     2040

gagaaggggc agctgctgga gtacatcctg accgatctcc gtgtgcccca cagctatgag     2100

gtccgcctca caccctatac caccttcggg gctggtgaca tggcctcccg catcatccac     2160

tacacagagc ccatcaactc tccgaacctt tcagacaaca cctgccactt tgaggatgag     2220

aagatctgtg gctataccca ggacctgaca gacaactttg actggacgcg gcagaatgcc     2280

ctcacccaga accccaaacg ctcccccaac actggtcccc ccaccgacat aagtggcacc     2340

cctgagggct actacatgtt catcgagaca tcgaggcctc gggagctggg ggaccgtgca     2400

aggttagtga gtcccctcta caatgccagc gccaagttct actgtgtctc cttcttctac     2460

cacatgtacg ggaaacacat cggctccctc aacctcctgg tgcggtcccg gaacaaaggg     2520

gctctggaca cgcacgcctg gtctctcagt ggcaataagg gcaatgtgtg gcagcaggcc     2580

catgtgccca tcagccccag tgggcccttc cagattattt ttgagggggt tcgaggcccg     2640

ggctacctgg gggatattgc catagatgac gtcacactga agaaggggga gtgtccccgg     2700

aagcagacgg atcccaataa agtggtggtg atgccgggca gt                        2742


<210>  4023
<211>  909
<212>  DNA
<213>  Homo Sapiens

<400>  4023
ccagtagtaa ctgttcatca aagtataggt gaagctaaag aacaatttta ctatgagaga       60

acagtgttcc tccggtgtgt tgccaattcc aatcctcctg ttcggtatag ctggagacgt      120

ggccaggagg tcttgctgca aggatctgat aaaggagttg agatttatga accattcttt      180

acccagggtg aaacaaagat cttaaaacta aagaatcttc gacctcagga ctatgctaat      240

tatagctgca ttgcttcagt gaggaatgta tgtaatattc ctgataagat ggtgtcgttt      300

agactgtcca ataaaacagc atcaccgtca attaaactct tggtggatga tcctatagtt      360

gtaaatcctg gagaggccat aacattagta tgtgttacaa caggaggaga gcctgcacct      420

tctctcacct gggtcaggtc ctttgggact ctgcctgaaa agactgtttt gaatggagga      480

actttgacca tacctgccat cacctcagat gatgctggta cttacagctg cattgccaat      540

aataatgtgg gaaaccctgc aaaaaagtcc accaacatca ttgtgagagc attaaaaaaa      600

ggacgatttt ggatcacacc agatccttat cacaaagatg acaacatcca gattggccgt      660

gaggtgaaaa tatcttgcca agtagaagct gttccttctg aggagctaac atttagttgg      720

tttaaaaatg gtcgtccatt aagaagttct gagcggatgg tcattacaca gactgatcct      780

gatgtctctc cgggaacaac aaacttggac atcattgatt taaaattcac ggattttggg      840

acgtacacat gtgtagcatc tctgaaggga ggaggaatat ctgatatcag tatcgatgtt      900

aatatatcc                                                              909


<210>  4024
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  4024
ctgaatcttg aagaccctaa tgtgtgtagc cactgggaaa gctactcagt gactgtgcaa       60

gagtcatacc cacatccctt tgatcaaatt tactacacga gctgcactga cattctaaac      120

tggtttaaat gcacgcggca cagagtcagc tatcggacag cctatcgaca tggggagaag      180

actatgtata ggcgcaagtc tcagtgttgt cctggatttt atgaaagcgg ggaaatgtgt      240

gtcccccact gtgctgataa atgtgtccat ggtcgctgta ttgctccaaa cacctgtcag      300

tgtgagcctg gctggggagg gaccaactgc tccagtgcct gcgatggtga tcactggggt      360

ccccactgca ccagccggtg ccagtgcaaa aatggggctc tgtgcaaccc catcaccggg      420

gcttgccact gtgctgcggg cttccggggc tggcgctgcg aggaccgctg tgagcagggc      480

acctatggta acgactgtca tcagagatgc cagtgccaga atggagccac ctgcgaccac      540

gtcacggggg aatgccgctg cccaccagga tacaccggag ccttctgtga ggatctttgt      600

cctcctggta aacatggtcc acagtgtgag cagagatgcc cttgtcaaaa tggaggagtg      660

tgtcatcacg tcactggaga atgctcttgc ccttctggct ggatgggcac agtgtgtggt      720

cagccttgcc ccgagggtcg ctttggaaag aactgttccc aagaatgcca gtgccataat      780

ggagggacgt gtgatgctgc cacaggccaa tgtcattgca gtccaggata cacaggggaa      840

cggtgccagg atgagtgtcc tgttgggacc tatggcgttc tctgtgctga gacctgccag      900

tgtgtcaacg gagggaagtg ttaccacgtg agcggcgcat gcctctgtga agcaggcttt      960

gctggcgagc gctgcgaagc acgcctgtgt cctgaggggc tctacggcat caaatgtgac     1020

aaacggtgtc cctgccactt ggaaaacact catagctgtc accccatgtc tggagagtgt     1080

gcctgcaagc cgggctggtc aggactctac tgtaatgaga catgttctcc tggattctac     1140

ggggaagctt gccagcagat ctgcagctgc caaaatgggg cagactgtga cagtgtgact     1200

ggaaagtgca cctgtgcccc aggattcaaa ggaattgact gctctacccc atgccctctg     1260

ggaacctatg ggataaactg ttcctctcgc tgtggctgta aaaatgatgc agtctgctct     1320

cctgtggacg ggtcttgtac ttgcaaggca ggctggcacg gggtggactg ctccatcaga     1380

tgtcccagtg gcacatgggg ctttggctgt aacttaacat gccagtgcct caacggggga     1440

gcctgcaaca ccctggacgg gacctgcacg tgtgcacctg gatggcgcgg ggagaaatgc     1500

gaacttccct gccaggatgg cacgtacggg ctgaactgtg ctgagcgctg cgactgcagc     1560

cacgcagatg gctgccaccc taccacgggc cattgccgct gcctccccgg atggtcagga     1620

ttgttt                                                                1626


<210>  4025
<211>  2487
<212>  DNA
<213>  Homo Sapiens

<400>  4025
ctgaaccccg aggaccccaa cgtgtgcagc cactgggaga gctatgctgt gactgtccag       60

gaatcgtatg cacacccctt cgatcagatc tattacacac gatgcacaga catcctcaac      120

tggttcaagt gcaccaggca ccggatcagt tataagacgg cgtatcggag aggcctccgg      180

accatgtacc ggcggaggtc ccagtgctgc cctggctact atgagaacgg agacttctgc      240

atacccctgt gtacggagga gtgtgtgcac ggccgctgcg tttccccgga cacctgccac      300

tgcgagcctg gctggggagg gcccgactgc tccagcggct gcgacagcga ccactggggg      360

ccccactgca gcaaccggtg ccagtgccag aacggcgccc tgtgtaaccc catcacaggc      420

gcctgcgtgt gcgccgccgg cttccgtgga tggcgctgcg aggagctctg cgcgcctggc      480

acccacggca agggatgcca gctgccgtgc cagtgccgac acggtgccag ctgcgacccc      540

cgcgccggcg agtgcctctg cgcacctggc tacaccggcg tctactgcga ggagctgtgc      600

cctcctggga gccatggagc tcactgtgag ctgcgctgcc cctgtcagaa tgggggcacc      660

tgccaccaca tcactggcga gtgtgcctgc cccccaggct ggacgggagc agtgtgtgcc      720

cagccctgcc caccagggac atttggccag aactgcagcc aggattgtcc ttgccaccat      780

ggagggcagt gtgaccacgt gactggacag tgccactgta cagctggata catgggggac      840

aggtgccaag aggagtgccc cttcgggtcc ttcggcttcc agtgctcaca gcgctgtgac      900

tgccacaatg gggggcagtg ttcacccacc acgggtgcct gcgagtgtga gcctggctac      960

aagggcccac gctgccagga gcgactgtgc ccggagggcc tgcatggccc aggctgcacc     1020

ctgccctgcc cctgtgacgc tgacaacacc atcagctgcc acccagtaac tggagcttgt     1080

acctgccagc caggctggtc tggtcaccac tgcaatgaat cctgccctgt tggctactat     1140

ggcgatggct gccagctgcc ttgcacctgt cagaatggcg ccgactgcca cagcatcact     1200

gggggctgca cttgtgctcc gggcttcatg ggagaggtct gtgccgtttc ctgtgcagca     1260

gggacctatg gccccaactg ctcgtccatc tgtagctgta acaatggtgg cacctgctcc     1320

ccagtagatg gctcctgtac ctgcaaggaa gggtggcagg gcctggactg caccctgcca     1380

tgtcccagtg ggacgtgggg cctgaactgc aacgagagct gcacctgtgc caatggggca     1440

gcctgcagcc ccatagacgg ctcctgctcc tgcactcctg gctggctggg agacacctgt     1500

gagctgcctt gcccggatgg cacatttggg ctgaactgca gtgaacactg tgactgcagc     1560

catgctgatg gatgtgaccc cgtcacaggc cactgctgct gcctggccgg atggacaggc     1620

atccgctgtg acagcacgtg tccacctggc cgctggggcc ccaactgctc tgtctcctgc     1680

agctgtgaga atggaggctc ctgctcccca gaggatggga gctgcgagtg tgcccctggc     1740

ttccgaggac ccttatgcca gagaatctgc ccccctgggt tctatggcca cggctgcgcc     1800

cagccatgcc ccctctgcgt gcacagcagc aggccctgcc accacatcag cggcatctgt     1860

gagtgcctcc caggattctc tggagctctc tgcaaccaag tgtgtgctgg aggatacttt     1920

gggcaggact gtgcccagct ctgctcctgt gccaacaacg ggacctgcag ccctatcgat     1980

ggctcctgcc agtgctttcc tggatggatt ggcaaggact gctcacaggc ttgcccaccc     2040

gggttctggg gccccgcctg cttccacgca tgcagctgcc acaacggggc gagctgcagc     2100

gccgaggacg gggcctgcca ctgcacccct ggctggactg gactcttctg cacacagcgc     2160

tgcccagcag cattttttgg gaaggactgt gggcgcgtat gccagtgtca gaatggcgcc     2220

agctgtgacc acatcagtgg caagtgcacc tgccgcacag gcttcaccgg gcaacactgt     2280

gagcagagat gtgccccagg aacctttggc tatgggtgtc agcagctatg tgagtgcatg     2340

aacaactcca cctgtgacca tgtcaccggc acctgttact gcagccctgg cttcaaagga     2400

atcaggtgtg accaagctgc cctcatgatg gaggagctga atccctacac caagatcagc     2460

ccagcactgg gtgcagagcg gcactcg                                         2487


<210>  4026
<211>  1587
<212>  DNA
<213>  Homo Sapiens

<400>  4026
gccgtcgcct cagccgcctc ggcggggaat gtcaccggtg gcggcggggc cgcggggcag       60

gtggacgcgt cgccgggccc cgggttgcgg ggcgagccca gccacccctt ccctagggcg      120

acggctccca cggcccaggc cccgaggacc gggcccccgc gcgccaccgt ccaccgaccc      180

ctggctgcga cttctccagc ccagtccccg gagaccaccc ctctttgggc gactgctgga      240

ccctcttcca ccacctttca ggcgccgctc ggcccctcgc cgaccacccc tccggcggcg      300

gaacgcactt cgaccacctc tcaggcgccg accagacccg cgccgaccac cctttcgacg      360

accactggcc cggcgccgac cacccctgta gcgaccaccg taccggcgcc cacgactccc      420

cggaccccga cccccgatct ccccagcagc agcaacagca gcgtcctccc caccccacct      480

gccaccgagg ccccctcttc gcctcctcca gggcatcagt ggcctgtggc aaagatgccc      540

caaaagtatc taggaaaata tgcctgtgag agtaacctga aaagcaagta cttgcctctt      600

acacagccag tcatgaatct tagagtctca gaagctgtta aaacggagta tgtatgtaac      660

tgctctgtgg ttggaagcct gaatgtgaat cgctgcaacc agaccacagg gcagtgtgag      720

tgtcggccag gttatcaggg gcttcactgt gaaacctgca aagagggctt ttacctaaat      780

tacacttctg ggctctgtca gccatgtgac tgtagtccac atggagctct cagcataccg      840

tgcaacagtt ctgggaaatg ccagtgcaaa gtgggtgtca ttggctctat atgtgaccga      900

tgccaagatg gatattatgg ctttagtaag aatggctgct tgccctgcca atgcaataat      960

cggtctgcca gttgcgatgc cctcacaggt gcttgtttaa actgccagga aaatagcaaa     1020

ggaaatcact gtgaagaatg taaagaagga ttttatcaga gtcctgatgc cactaaagaa     1080

tgtcttcgct gcccttgttc agcagtgaca tctacaggca gctgctctat aaaatcgagt     1140

gaattggaac ctgaatgtga ccagtgtaaa gatggttaca taggcccgaa ctgcaataaa     1200

tgtgaaaatg gctattacaa ttttgacagc atctgtagaa agtgccaatg tcacggccat     1260

gtggacccag ttaaaactcc aaagatttgt aagcccgaga gtggtgagtg catcaactgc     1320

ctccataaca ccactgggtt ttggtgtgag aactgcctag aaggttatgt tcacgacctc     1380

gagggaaatt gcatcaagaa agaagttatt cttccaacac ctgaaggttc taccattttg     1440

gtttccaatg cctctttgac cacatcagtg cccacccctg ttataaatag tacttttacc     1500

cctacaaccc tgcagactat cttttcagta agcacttctg aaaacagcac ttcagcttta     1560

gctgatgtat catggaccca atttaac                                         1587


<210>  4027
<211>  1941
<212>  DNA
<213>  Homo Sapiens

<400>  4027
aatggcctga gagacccaaa caccaggtgg acgttcccca ttccttacat cttggctgat       60

aatttggggc tgaatgctaa aggagccatt ctgtatgcct ttgagatgtt ccgtctcaag      120

tcctgtgtgg atttcaagcc ctatgaagga gagagctcat atatcatatt tcaacagttt      180

gatgggtgct ggtctgaggt tggtgaccaa catgtgggac agaacatttc cattggccaa      240

ggatgtgcct ataaggccat catagaacac gagatcctgc atgctttggg attttaccac      300

gagcagtcaa ggacggaccg ggatgattat gtgaacatct ggtgggacca aattctttca      360

ggttaccagc acaactttga cacctatgat gatagcttaa tcacagacct caatacaccc      420

tatgattatg agtctttgat gcactaccag cctttctcat ttaacaagaa tgcaagtgtt      480

cccaccatca cagccaagat ccctgagttt aactccatta tcggacaacg cctggatttc      540

agtgccattg atttagagag gctgaaccga atgtacaatt gcaccacaac tcacactctt      600

ttggaccact gtacttttga gaaggcaaac atctgtggaa tgattcaggg caccagagat      660

gacactgact gggcccatca ggacagtgct caggctggag aagtggatca caccttgttg      720

ggacaatgca caggtgccgg ctacttcatg cagttcagca ccagctcggg gtccgcggaa      780

gaggcagccc tactggagtc tcggattctt tacccaaaga ggaagcagca gtgcctgcaa      840

tttttctata aaatgacggg aagtccttca gacagactcg ttgtctgggt caggagggat      900

gacagcacag gcaatgttcg caagttggtg aaggtgcaga cttttcaagg agatgatgac      960

cacaattgga aaattgccca tgtggtgctc aaagaggaac agaagtttcg ctaccttttc     1020

cagggcacaa aaggcgaccc tcagaactca actgggggaa tttacctaga tgacatcact     1080

ctgacagaaa ccccctgccc cacaggggtc tggacagtcc ggaatttctc ccaagtcctt     1140

gagaacacca gcaaagggga caagcttcag agccctcgat tctacaattc ggagggatat     1200

ggttttgggt taactttata cccaaatagc ggagaaagct ctggttactt gagacttgct     1260

tttcatgtgt gcagtgggga gaacgatgct atcctggagt ggccggtaga aaacagacag     1320

gtgataatta ccatccttga ccaggagcct gatgtccgga acaggatgtc ctcaagcatg     1380

gtgttcacta cctcgaagtc gcacacatct ccagcgataa atgacactgt catctgggac     1440

aggccgtcca gggtgggaac ctatcataca gactgtaatt gttttagaag catcgacttg     1500

ggctggagtg gtttcatttc ccaccaaatg ctgaaaagga ggagtttcct gaaaaatgat     1560

gacctcatca tatttgtgga ctttgaagat atcacccacc tcagccagac tgaagttccc     1620

actaaaggca aaagactgag cccccaaggc ctcattctcc aaggccagga gcagcaggtc     1680

tccgaagaag gttcgggaaa ggccatgtta gaggaagccc tacctgtcag cctgagccag     1740

gggcagccca gccgacagaa gcggtcggtg gagaacacag gccccctgga ggaccataac     1800

tggccacagt acttcagaga cccatgtgac ccaaaccctt gccaaaatga cggcatctgt     1860

gtgaacgtga aggggatggc gagctgcagg tgcatctctg gacatgcttt cttctacacg     1920

ggggagcgct gtcaggccgt g                                               1941


<210>  4028
<211>  1773
<212>  DNA
<213>  Homo Sapiens

<400>  4028
aattccatca ttggagaaaa gtatagatgg cctcatacca ttccatatgt tctagaagat       60

agcttggaaa tgaatgctaa gggagttatc ctcaatgcat ttgaacgtta tcgccttaaa      120

acatgtattg actttaagcc ttgggctgga gaaacaaact atatatcagt gttcaagggc      180

agtggctgct ggtcttcagt aggaaatagg cgggttggga agcaagaact ttccatcggg      240

gcaaactgtg accgaatagc aacagttcaa cacgagttcc tccacgctct gggattctgg      300

catgagcagt cgcgttctga ccgggatgac tatgtcagga taatgtggga cagaattctg      360

tcaggcagag agcacaattt taacacctat agtgacgata tatcagattc cctgaatgtt      420

ccctatgatt acacttcagt aatgcactac agtaaaactg cattccaaaa tggaacagag      480

ccgacaattg tcacaagaat ctcagacttt gaggatgtga tcggccaacg aatggatttc      540

agtgactctg atctcctaaa gttgaatcaa ctgtataact gctcctcttc cttgagtttt      600

atggactcgt gcagttttga actggaaaat gtgtgtggca tgatccaaag ttcaggagat      660

aatgctgact ggcaacgggt ttcacaggtt cccagggggc cagagagtga tcactccaac      720

atgggccagt gccaaggttc tggtttcttc atgcatttcg atagcagctc tgtaaatgtg      780

ggggccacag cagtgctgga aagtagaacg ctgtacccta aaagaggatt tcagtgcctg      840

caattttact tatataacag tggcagtgaa agtgatcaac tgaacatcta tatcagggag      900

tattctgcag acaatgtgga tggcaattta acccttgtgg aagaaataaa agaaataccc      960

actgggagct ggcaacttta tcatgtaaca ttgaaagtga ccaagaagtt tagagtggtg     1020

tttgaaggac gcaaaggctc tggtgcatca ctgggtggtc tgtctattga tgacatcaat     1080

ctttcggaaa cacggtgccc tcatcatatc tggcatataa ggaatttcac acagttcatt     1140

ggcagcccaa atggaactct gtatagccct ccattttact cttctaaagg ttatgccttt     1200

cagatttact taaatctagc ccatgtgact aatgcaggga tatatttcca cttgatctct     1260

ggagccaatg atgatcaatt acagtggcca tgtccttggc aacaagccac aatgacactt     1320

ttggatcaaa atcctgacat tcgacagcgt atgtccaatc agcggagtat aactacagac     1380

ccatttatga ccaccgataa tggaaactat ttctgggaca ggccttccaa agtgggaaca     1440

gtggctttgt tccctaatgg aactcagttt agaagaggtg ggggctatgg aaccagtgcc     1500

tttataaccc acgaaaggct gaaaagcaga gattttataa aaggagatga tgtttatatc     1560

ctactgacag tggaagacat atctcacctc aactctacac aaatccagct aacaccagcc     1620

cctagtgttc aagacctctg ctcaaaaacc acctgtaaaa atgacggtgt ctgcactgtt     1680

cgagatggca aagctgagtg caggtgccag tcaggggaag actggtggta catgggagaa     1740

aggtgtgaaa agagaggctc cacccgagac acc                                  1773


<210>  4029
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  4029
cctcacttta ctaagcagcc tgagagcatg aatgtcacca gaaacacagc cttcaacctc       60

acctgtcagg ctgtgggccc gcctgagccc gtcaacattt tctgggttca aaacagtagc      120

cgtgttaacg aacagcctga aaaatccccc tccgtgctaa ctgttccagg cctgacggag      180

atggcggtct tcagttgtga ggcccacaat gacaaagggc tgaccgtgtc caagggagtg      240

cagatcaaca tcaaagcaat tccctcccca ccaactgaag tcagcatccg taacagcact      300

gcacacagca ttctgatctc ctgggttcct ggttttgatg gatactcccc gttcaggaat      360

tgcagcattc aggtcaagga agctgatccg ctgagtaatg gctcagtcat gatttttaac      420

acctctgcct taccacatct gtaccaaatc aagcagctgc aagccctggc taattacagc      480

attggtgttt cctgcatgaa tgaaataggc tggtctgcag tgagcccttg gattctagcc      540

agcacgactg aaggagcccc atcagtagca cctttaaatg tcactgtgtt tctgaatgaa      600

tctagtgata atgtggacat cagatggatg aagcctccga ctaagcagca ggatggagaa      660

ctggtgggct accggatatc ccacgtgtgg cagagtgcag ggatttccaa agagctcttg      720

gaggaagttg gccagaatgg cagccgagct cggatctctg ttcaagtcca caatgctacg      780

tgcacagtga ggattgcagc cgtcaccaaa gggggagttg ggcccttcag tgatccagtg      840

aaaatattta tccctgcaca cggttgggta gattatgccc cctcttcaac tccggcgcct      900

ggcaacgcag atcctgtgct catcatc                                          927


<210>  4030
<211>  2724
<212>  DNA
<213>  Homo Sapiens

<400>  4030
gagtgtaaag aggcactagc aaagtccgag atgaatgtga atatgaagta tcagcttccc       60

aacttcaccg cggaaacacc catccagaat gtcattctac atgagcatca cattttcctt      120

ggtgccacta actacattta tgttttaaat gaggaagacc ttcagaaggt tgctgagtac      180

aagactgggc ctgtgctgga acacccagat tgtttcccat gtcaggactg cagcagcaaa      240

gccaatttat caggaggtgt ttggaaagat aacatcaaca tggctctagt tgtcgacacc      300

tactatgatg atcaactcat tagctgtggc agcgtcaaca gagggacctg ccagcgacat      360

gtctttcccc acaatcatac tgctgacata cagtcggagg ttcactgcat attctcccca      420

cagatagaag agcccagcca gtgtcctgac tgtgtggtga gcgccctggg agccaaagtc      480

ctttcatctg taaaggaccg gttcatcaac ttctttgtag gcaataccat aaattcttct      540

tatttcccag atcatccatt gcattcgata tcagtgagaa ggctaaagga aacgaaagat      600

ggttttatgt ttttgacgga ccagtcctac attgatgttt tacctgagtt cagagattct      660

taccccatta agtatgtcca tgcctttgaa agcaacaatt ttatttactt cttgacggtc      720

caaagggaaa ctctagatgc tcagactttt cacacaagaa taatcaggtt ctgttccata      780

aactctggat tgcattccta catggaaatg cctctggagt gtattctcac agaaaagaga      840

aaaaagagat ccacaaagaa ggaagtgttt aatatacttc aggctgcgta tgtcagcaag      900

cctggggccc agcttgctag acaaatagga gccagcctga atgatgacat tcttttcggg      960

gtgttcgcac aaagcaagcc agattctgcc gaaccaatgg atcgatctgc catgtgtgca     1020

ttccctatca aatatgtcaa cgacttcttc aacaagatcg tcaacaaaaa caatgtgaga     1080

tgtctccagc atttttacgg acccaatcat gagcactgct ttaataggac acttctgaga     1140

aattcatcag gctgtgaagc gcgccgtgat gaatatcgaa cagagtttac cacagctttg     1200

cagcgcgttg acttattcat gggtcaattc agcgaagtcc tcttaacatc tatatccacc     1260

ttcattaaag gagacctcac catagctaat cttgggacat cagagggtcg cttcatgcag     1320

gttgtggttt ctcgatcagg accatcaacc cctcatgtga attttctcct ggactcccat     1380

ccagtgtctc cagaagtgat tgtggagcat acattaaacc aaaatggcta cacactggtt     1440

atcactggga agaagatcac gaagatccca ttgaatggct tgggctgcag acatttccag     1500

tcctgcagtc aatgcctctc tgccccaccc tttgttcagt gtggctggtg ccacgacaaa     1560

tgtgtgcgat cggaggaatg cctgagcggg acatggactc aacagatctg tctgcctgca     1620

atctacaagg ttttcccaaa tagtgcaccc cttgaaggag ggacaaggct gaccatatgt     1680

ggctgggact ttggatttcg gaggaataat aaatttgatt taaagaaaac tagagttctc     1740

cttggaaatg agagctgcac cttgacttta agtgagagca cgatgaatac attgaaatgc     1800

acagttggtc ctgccatgaa taagcatttc aatatgtcca taattatttc aaatggccac     1860

gggacaacac aatacagtac attctcctat gtggatcctg taataacaag tatttcgccg     1920

aaatacggtc ctatggctgg tggcacttta cttactttaa ctggaaatta cctaaacagt     1980

gggaattcta gacacatttc aattggtgga aaaacatgta ctttaaaaag tgtgtcaaac     2040

agtattcttg aatgttatac cccagcccaa accatttcaa ctgagtttgc tgttaaattg     2100

aaaattgact tagccaaccg agagacaagc atcttcagtt accgtgaaga tcccattgtc     2160

tatgaaattc atccaaccaa atcttttatt agtggtggga gcacaataac aggtgttggg     2220

aaaaacctga attcagttag tgtcccgaga atggtcataa atgtgcatga agcaggaagg     2280

aactttacag tggcatgtca acatcgctct aattcagaga taatctgttg taccactcct     2340

tccctgcaac agctgaatct gcaactcccc ctgaaaacca aagccttttt catgttagat     2400

gggatccttt ccaaatactt tgatctcatt tatgtacata atcctgtgtt taagcctttt     2460

gaaaagccag tgatgatctc aatgggcaat gaaaatgtac tggaaattaa gggaaatgat     2520

attgaccctg aagcagttaa aggtgaagtg ttaaaagttg gaaataagag ctgtgagaat     2580

atacacttac attctgaagc cgttttatgc acggtcccca atgacctgct gaaattgaac     2640

agcgagctaa atatagagtg gaagcaagca atttcttcaa ccgtccttgg aaaagtaata     2700

gttcaaccag atcagaattt caca                                            2724


<210>  4031
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  4031
gcttttgttt tggaagatgt ggacttcgac caaatggttt cactggaagc aaatcgtagt       60

tcttacaatg catcctttcc ctcaagcttt gaactctcag caagttccca ctcggatgat      120

gacgtcatca tagccaaaga gggaactagc gtttcaattg agtgtcttct cacagccagt      180

cactatgaag atgtccattg gcacaattca aaaggacagc aactggatgg cagaagcaga      240

ggtggaaagt ggttggtttc tgataacttc ctaaacatca ccaatgtagc ttttgatgac      300

cgtgggctct atacctgttt cgtcacctct ccaattcgtg cctcctactc tgtcacccta      360

cgtgttatct tcacctcggg agacatg                                          387


<210>  4032
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4032
aaatctgtca ctaattctac gttgaacggt actaatgtag tgctgggctc cgttccagtc       60

ataatcgcta gaaccgatca cataattgtg aaagaaggca acagcgctct gataaattgc      120

tccgtctatg gcatacccga cccccagttc aagtggtaca actcaatagg gaaactactg      180

aaagaagaag aagatgagaa ggagcgtggg gggggtaagt ggcaaatgca tgacagtggt      240

ttgttgaaca taactaaggt gtctttttcc gatcgtggga aatatacttg tgtcgcaagt      300

aacatttacg ggacggtaaa taacaccgtc acgttaagag tcatctttac atccggggat      360

atg                                                                    363


<210>  4033
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  4033
ctggatatct gttccaaaaa cccctgccac aacggtggtt tatgcgagga gatttcccaa       60

gaagtgcgag gagatgtctt cccctcgtac acctgcacgt gccttaaggg ctacgcgggc      120

aaccactgtg agacgaaatg tgtcgagcca ctgggcatgg agaatgggaa cattgccaac      180

tcacagatcg ccgcctcatc tgtgcgtgtg accttcttgg gtttgcagca ttgggtcccg      240

gagctggccc gcctgaaccg cgcaggcatg gtcaatgcct ggacacccag cagcaatgac      300

gataacccct ggatccaggt gaacctgctg cggaggatgt gggtaacagg tgtggtgacg      360

cagggtgcca gccgcttggc cagtcatgag tacctgaagg ccttcaaggt ggcctacagc      420

cttaatggac acgaattcga tttcatccat gatgttaata aaaaacacaa ggagtttgtg      480

ggtaactgga acaaaaacgc ggtgcatgtc aacctgtttg agacccctgt ggaggctcag      540

tacgtgagat tgtaccccac gagctgccac acggcctgca ctctgcgctt tgagctactg      600

ggctgtgagc tgaacggatg cgccaatccc ctgggcctga agaataacag catccctgac      660

aagcagatca cggcctccag cagctacaag acctggggct tgcatctctt cagctggaac      720

ccctcctatg cacggctgga caagcagggc aacttcaacg cctgggttgc ggggagctac      780

ggtaacgatc agtggctgca gatcttccct ggcaactggg acaaccactc ccacaagaag      840

aacttgtttg agacgcccat cctggctcgc tatgtgcgca tcctgcctgt agcctggcac      900

aaccgcatcg ccctgcgcct ggagctgctg ggctgt                                936


<210>  4034
<211>  2070
<212>  DNA
<213>  Homo Sapiens

<400>  4034
ggcatggagg tgcggtggtg cgccacctcg gacccagagc agcacaagtg cggcaacatg       60

agcgaggcct tccgggaagc gggcatccag ccctccctcc tctgcgtccg gggcacctcc      120

gccgaccact gcgtccagct catcgcggcc caggaggctg acgccatcac tctggatgga      180

ggagccatct atgaggcggg aaaggagcac ggcctgaagc cggtggtggg cgaagtgtac      240

gatcaagagg tcggtacctc ctattacgcc gtggctgtgg tcaggaggag ctcccatgtg      300

accattgaca ccctgaaagg cgtgaagtcc tgccacacgg gcatcaatcg cacagtgggc      360

tggaacgtgc ccgtgggcta cctggtggag agcggccgcc tctcggtgat gggctgcgat      420

gtactcaaag ctgtcagcga ctattttggg ggcagctgcg tcccgggggc aggagagacc      480

agttactctg agtccctctg tcgcctctgc aggggtgaca gctctgggga aggggtgtgt      540

gacaagagcc ccctggagag atactacgac tacagcgggg ccttccggtg cctggcggaa      600

ggggcagggg acgtggcttt tgtgaagcac agcacggtac tggagaacac ggatgggaag      660

acgcttccct cctggggcca ggccctgctg tcacaggact tcgagctgct gtgccgggat      720

ggtagccggg ccgatgtcac cgagtggagg cagtgccatc tggcccgggt gcctgctcac      780

gccgtggtgg tccgggccga cacagatggg ggcctcatct tccggctgct caacgaaggc      840

cagcgtctgt tcagccacga gggcagcagc ttccagatgt tcagctctga ggcctatggc      900

cagaaggatc tactcttcaa agactctacc tcggagcttg tgcccatcgc cacacagacc      960

tatgaggcgt ggctgggcca tgagtacctg cacgccatga agggtctgct ctgtgacccc     1020

aaccggctgc ccccctacct gcgctggtgt gtgctctcca ctcccgagat ccagaagtgt     1080

ggagacatgg ccgtggcctt ccgccggcag cggctcaagc cagagatcca gtgcgtgtca     1140

gccaagtccc cccaacactg catggagcgg atccaggctg agcaggtcga cgctgtgacc     1200

ctgagtggcg aggacattta cacggcgggg aagacgtacg gcctggttcc cgcagccggg     1260

gagcactatg ccccggaaga cagcagcaac tcgtactacg tggtggccgt ggtgagacgg     1320

gacagctccc acgccttcac cttggatgag cttcggggca agcgctcctg ccacgccggt     1380

ttcggcagcc ctgcaggctg ggatgtcccc gtgggtgccc ttattcagag aggcttcatc     1440

cggcccaagg actgtgacgt cctcacagca gtgagcgagt tcttcaatgc cagctgcgtg     1500

cccgtgaaca accccaagaa ctacccctcc tcgctgtgtg cactgtgcgt gggggacgag     1560

cagggccgca acaagtgtgt gggcaacagc caggagcggt attacggcta ccgcggcgcc     1620

ttcaggtgcc tggtggagaa tgcgggtgac gttgccttcg tcaggcacac aaccgtcttt     1680

gacaacacaa acggccacaa ttccgagccc tgggctgctg agctcaggtc agaggactat     1740

gaactgctgt gccccaacgg ggcccgagcc gaggtgtccc agtttgcagc ctgcaacctg     1800

gcacagatac caccccacgc cgtgatggtc cggcccgaca ccaacatctt caccgtgtat     1860

ggactgctgg acaaggccca ggacctgttt ggagacgacc acaataagaa cgggttcaaa     1920

atgttcgact cctccaacta tcatggccaa gacctgcttt tcaaggatgc caccgtccgg     1980

gcggtgcctg tcggagagaa aaccacctac cgcggctggc tggggctgga ctacgtggcg     2040

gcgctggaag ggatgtcgtc tcagcagtgc                                      2070


<210>  4035
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  4035
gagccccaca gtcttcgtta taacctcacg gtgctgtcct gggatggatc tgtgcagtca       60

gggtttctca ctgaggtaca tctggatggt cagcccttcc tgcgctgtga caggcagaaa      120

tgcagggcaa agccccaggg acagtgggca gaagatgtcc tgggaaataa gacatgggac      180

agagagacca gagacttgac agggaacgga aaggacctca ggatgaccct ggctcatatc      240

aaggaccaga aagaaggctt gcattccctc caggagatta gggtctgtga gatccatgaa      300

gacaacagca ccaggagctc ccagcatttc tactacgatg gggagctctt cctctcccaa      360

aacctggaga ctgaggaatg gacaatgccc cagtcctcca gagctcagac cttggccatg      420

aacgtcagga atttcttgaa ggaagatgcc atgaagacca agacacacta tcacgctatg      480

catgcagact gcctgcagga actacggcga tatctaaaat ccggcgtagt cctgaggaga      540

acagtgcccc ccatggtgaa tgtcacccgc agcgaggcct cagagggcaa cattaccgtg      600

acatgcaggg cttctggctt ctatccctgg aatatcacac tgagctggcg tcaggatggg      660

gtatctttga gccacgacac ccagcagtgg ggggatgtcc tgcctgatgg gaatggaacc      720

taccagacct gggtggccac caggatttgc caaggagagg agcagaggtt cacctgctac      780

atggaacaca gcgggaatca cagcactcac cctgtgccct ctgggaaagt gctggtgctt      840

cagagtcatt gg                                                          852


<210>  4036
<211>  732
<212>  DNA
<213>  Homo Sapiens

<400>  4036
gctgagcccc acagtcttcg ttacaacctc atggtgctgt cccaggatgg atctgtgcag       60

tcagggtttc tcgctgaggg acatctggat ggtcagccct tcctgcgcta tgacaggcag      120

aaacgcaggg caaagcccca gggacagtgg gcagaagatg tcctgggagc tgagacctgg      180

gacacagaga ccgaggactt gacagagaat gggcaagacc tcaggaggac cctgactcat      240

atcaaggacc agaaaggagt gccccagtcc tccagagctc agaccttggc tatgaacgtc      300

acaaatttct ggaaggaaga tgccatgaag accaagacac actatcgcgc tatgcaggca      360

gactgcctgc agaaactaca gcgatatctg aaatccgggg tggccatcag gagaacagtg      420

ccccccatgg tgaatgtcac ctgcagcgag gtctcagagg gcaacatcac cgtgacatgc      480

agggcttcca gcttctatcc ccggaatatc acactgacct ggcgtcagga tggggtatct      540

ttgagccaca acacccagca gtggggggat gtcctgcctg atgggaatgg aacctaccag      600

acctgggtgg ccaccaggat tcgccaagga gaggagcaga ggttcacctg ctacatggaa      660

cacagcggga atcacggcac tcaccctgtg ccctctggga aggcgctggt gcttcagagt      720

caacggacag ac                                                          732


<210>  4037
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  4037
ccgatgttca tcgtaaacac caacgtgccc cgcgcctccg tgccggacgg gttcctctcc       60

gagctcaccc agcagctggc gcaggccacc ggcaagcccc cccagtacat cgcggtgcac      120

gtggtcccgg accagctcat ggccttcggc ggctccagcg agccgtgcgc gctctgcagc      180

ctgcacagca tcggcaagat cggcggcgcg cagaaccgct cctacagcaa gctgctgtgc      240

ggcctgctgg ccgagcgcct gcgcatcagc ccggacaggg tctacatcaa ctattacgac      300

atgaacgcgg ccaatgtggg ctggaacaac tccaccttcg cc                         342


<210>  4038
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  4038
agaaaagctg tattggattg tgaggcaatg aaaacaaatg aattcccttc tccatgtttg       60

gactcaaaga ctaaggtggt tatgaagggt caaaatgtat ctatgttttg ttcccataag      120

aacaaatcac tgcagatcac ctattcattg tttcgacgta agacacacct gggaacccag      180

gatggaaaag gtgaacctgc gatttttaac ctaagcatca cagaagccca tgaatcaggc      240

ccctacaaat gcaaagccca agttaccagc tgttcaaaat acagtcgtga cttcagcttc      300

acgattgtcg acccggtgac ttccccagtg ctgaacatta tggtcattca aacagaaaca      360

gaccgacata taacattaca ttgcctctca gtcaatggct cgctgcccat caattacact      420

ttctttgaaa accatgttgc catatcacca gctatttcca agtatgacag ggagcctgct      480

gaatttaact taaccaagaa gaatcctgga gaagaggaag agtataggtg tgaagctaaa      540

aacagattgc ctaactatgc aacatacagt caccctgtca ccatgccctc aacaggcgga      600

gacagctgtc ctttctgtct gaag                                             624


<210>  4039
<211>  1482
<212>  DNA
<213>  Homo Sapiens

<400>  4039
tacgccctca ccgggaggaa gtggaacaac caccatctga cctttagcat ccagaactac       60

acggagaagt tgggctggta ccactcgatg gaggcggtgc gcagggcctt ccgcgtgtgg      120

gagcaggcca cgcccctggt cttccaggag gtgccctatg aggacatccg gctgcggcga      180

cagaaggagg ccgacatcat ggtactcttt gcctctggct tccacggcga cagctcgccg      240

tttgatggca ccggtggctt tctggcccac gcctatttcc ctggccccgg cctaggcggg      300

gacacccatt ttgacgcaga tgagccctgg accttctcca gcactgacct gcatggaaac      360

aacctcttcc tggtggcagt gcatgagctg ggccacgcgc tggggctgga gcactccagc      420

aaccccaatg ccatcatggc accgttctac cagtggaagg acgttgacaa cttcaagctg      480

cccgaggacg atctccgtgg catccagcag ctctacggta ccccagacgg tcagccacag      540

cctacccagc ctctccccac tgtgacgcca cggcggccag gccggcctga ccaccggccg      600

ccccggcctc cccagccacc acccccaggt gggaagccag agcggccccc aaagccgggc      660

cctccagtcc agccccgagc cacagagcgg cccgaccagt atggccccaa catctgcgac      720

ggggactttg acacagtggc catgcttcgc ggggagatgt tcgtgttcaa gggccgctgg      780

ttctggcgag tccggcacaa ccgcgtcctg gacaactatc ccatgcccat cgggcacttc      840

tggcgtggtc tgcccggtga catcagtgct gcctacgagc gccaagacgg tcgttttgtc      900

tttttcaaag gtgaccgcta ctggctcttt cgagaagcga acctggagcc cggctaccca      960

cagccgctga ccagctatgg cctgggcatc ccctatgacc gcattgacac ggccatctgg     1020

tgggagccca caggccacac cttcttcttc caagaggaca ggtactggcg cttcaacgag     1080

gagacacagc gtggagaccc tgggtacccc aagcccatca gtgtctggca ggggatccct     1140

gcctccccta aaggggcctt cctgagcaat gacgcagcct acacctactt ctacaagggc     1200

accaaatact ggaaattcga caatgagcgc ctgcggatgg agcccggcta ccccaagtcc     1260

atcctgcggg acttcatggg ctgccaggag cacgtggagc caggcccccg atggcccgac     1320

gtggcccggc cgcccttcaa cccccacggg ggtgcagagc ccggggcgga cagcgcagag     1380

ggcgacgtgg gggatgggga tggggacttt ggggccgggg tcaacaagga cgggggcagc     1440

cgcgtggtgg tgcagatgga ggaggtggca cggacggtga ac                        1482


<210>  4040
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  4040
tatgcattga caggacagaa atggcagcac aagcacatca cttacagtat aaagaacgta       60

actccaaaag taggagaccc tgagactcgt aaagctattc gccgtgcctt tgatgtgtgg      120

cagaatgtaa ctcctctgac atttgaagaa gttccctaca gtgaattaga aaatggcaaa      180

cgtgatgtgg atataaccat tatttttgca tctggtttcc atggggacag ctctcccttt      240

gatggagagg gaggattttt ggcacatgcc tacttccctg gaccaggaat tggaggagat      300

acccattttg actcagatga gccatggaca ctaggaaatc ctaatcatga tggaaatgac      360

ttatttcttg tagcagtcca tgaactggga catgctctgg gattggagca ttccaatgac      420

cccactgcca tcatggctcc attttaccag tacatggaaa cagacaactt caaactacct      480

aatgatgatt tacagggcat ccagaagata tatggtccac ctgacaagat tcctccacct      540

acaagacctc taccgacagt gcccccacac cgctctattc ctccggctga cccaaggaaa      600

aatgacaggc caaaacctcc tcggcctcca accggcagac cctcctatcc cggagccaaa      660

cccaacatct gtgatgggaa ctttaacact ctagctattc ttcgtcgtga gatgtttgtt      720

ttcaaggacc agtggttttg gcgagtgaga aacaacaggg tgatggatgg atacccaatg      780

caaattactt acttctggcg gggcttgcct cctagtatcg atgcagttta tgaaaatagc      840

gacgggaatt ttgtgttctt taaaggtaac aaatattggg tgttcaagga tacaactctt      900

caacctggtt accctcatga cttgataacc cttggaagtg gaattccccc tcatggtatt      960

gattcagcca tttggtggga ggacgtcggg aaaacctatt tcttcaaggg agacagatat     1020

tggagatata gtgaagaaat gaaaacaatg gaccctggct atcccaagcc aatcacagtc     1080

tggaaaggga tccctgaatc tcctcaggga gcatttgtac acaaagaaaa tggctttacg     1140

tatttctaca aaggaaagga gtattggaaa ttcaacaacc agatactcaa ggtagaacct     1200

ggatatccaa gatccatcct caaggatttt atgggctgtg atggaccaac agacagagtt     1260

aaagaaggac acagcccacc agatgatgta gacattgtca tcaaactgga caacacagcc     1320

agcactgtga aagcc                                                      1335


<210>  4041
<211>  1320
<212>  DNA
<213>  Homo Sapiens

<400>  4041
caggctccag cccccaccaa gtggaacaag aggaacctgt cgtggagggt ccggacgttc       60

ccacgggact caccactggg gcacgacacg gtgcgtgcac tcatgtacta cgccctcaag      120

gtctggagcg acattgcgcc cctgaacttc cacgaggtgg cgggcagcac cgccgacatc      180

cagatcgact tctccaaggc caaccataac gacggctacc ccttcgacgg ccccggcggc      240

accgtggccc acgccttctt ccccggccac cacaacaccg ccggggacac ccactttgac      300

gatgacgagg cctggacctt ccgctcctcg gatgcccacg ggatggacct gtttgcagtg      360

gctgtccacg agtttggcca cgccattggg ttaagccatg tggccgctgc acactccatc      420

atgcggccgt actaccaggg cccggtgggt gacccgctgc gctacgggct cccctacgag      480

gacaaggtgc gcgtctggca gctgtacggt gtgcgggagt ctgtgtctcc cacggcgcag      540

cccgaggagc ctcccctgct gccggagccc ccagacaacc ggtccagcgc cccgcccagg      600

aaggacgtgc cccacagatg cagcactcac tttgacgcgg tggcccagat ccggggtgaa      660

gctttcttct tcaaaggcaa gtacttctgg cggctgacgc gggaccggca cctggtgtcc      720

ctgcagccgg cacagatgca ccgcttctgg cggggcctgc cgctgcacct ggacagcgtg      780

gacgccgtgt acgagcgcac cagcgaccac aagatcgtct tctttaaagg agacaggtac      840

tgggtgttca aggacaataa cgtagaggaa ggatacccgc gccccgtctc cgacttcagc      900

ctcccgcctg gcggcatcga cgctgccttc tcctgggccc acaatgacag gacttatttc      960

tttaaggacc agctgtactg gcgctacgat gaccacacga ggcacatgga ccccggctac     1020

cccgcccaga gccccctgtg gaggggtgtc cccagcacgc tggacgacgc catgcgctgg     1080

tccgacggtg cctactactt cttccgtggc caggagtact ggaaagtgct ggatggcgag     1140

ctggaggtgg cacccgggta cccacagtcc acggcccggg actggctggt gtgtggagac     1200

tcacaggccg atggatctgt ggctgcgggc gtggacgcgg cagaggggcc ccgcgcccct     1260

ccaggacaac atgaccagag ccgctcggag gacggttacg aggtctgctc atgcacctct     1320


<210>  4042
<211>  1653
<212>  DNA
<213>  Homo Sapiens

<400>  4042
tacaacttct tccctcgcaa gcccaagtgg gacaagaacc agatcacata caggatcatt       60

ggctacacac ctgatctgga cccagagaca gtggatgatg cctttgctcg tgccttccaa      120

gtctggagcg atgtgacccc actgcggttt tctcgaatcc atgatggaga ggcagacatc      180

atgatcaact ttggccgctg ggagcatggc gatggatacc cctttgacgg taaggacgga      240

ctcctggctc atgccttcgc cccaggcact ggtgttgggg gagactccca ttttgatgac      300

gatgagctat ggaccttggg agaaggccaa gtggtccgtg tgaagtatgg caacgccgat      360

ggggagtact gcaagttccc cttcttgttc aatggcaagg agtacaacag ctgcactgat      420

accggccgca gcgatggctt cctctggtgc tccaccacct acaactttga gaaggatggc      480

aagtacggct tctgtcccca tgaagccctg ttcaccatgg gcggcaacgc tgaaggacag      540

ccctgcaagt ttccattccg cttccagggc acatcctatg acagctgcac cactgagggc      600

cgcacggatg gctaccgctg gtgcggcacc actgaggact acgaccgcga caagaagtat      660

ggcttctgcc ctgagaccgc catgtccact gttggtggga actcagaagg tgccccctgt      720

gtcttcccct tcactttcct gggcaacaaa tatgagagct gcaccagcgc cggccgcagt      780

gacggaaaga tgtggtgtgc gaccacagcc aactacgatg acgaccgcaa gtggggcttc      840

tgccctgacc aagggtacag cctgttcctc gtggcagccc acgagtttgg ccacgccatg      900

gggctggagc actcccaaga ccctggggcc ctgatggcac ccatttacac ctacaccaag      960

aacttccgtc tgtcccagga tgacatcaag ggcattcagg agctctatgg ggcctctcct     1020

gacattgacc ttggcaccgg ccccaccccc acactgggcc ctgtcactcc tgagatctgc     1080

aaacaggaca ttgtatttga tggcatcgct cagatccgtg gtgagatctt cttcttcaag     1140

gaccggttca tttggcggac tgtgacgcca cgtgacaagc ccatggggcc cctgctggtg     1200

gccacattct ggcctgagct cccggaaaag attgatgcgg tatacgaggc cccacaggag     1260

gagaaggctg tgttctttgc agggaatgaa tactggatct actcagccag caccctggag     1320

cgagggtacc ccaagccact gaccagcctg ggactgcccc ctgatgtcca gcgagtggat     1380

gccgccttta actggagcaa aaacaagaag acatacatct ttgctggaga caaattctgg     1440

agatacaatg aggtgaagaa gaaaatggat cctggctttc ccaagctcat cgcagatgcc     1500

tggaatgcca tccccgataa cctggatgcc gtcgtggacc tgcagggcgg cggtcacagc     1560

tacttcttca agggtgccta ttacctgaag ctggagaacc aaagtctgaa gagcgtgaag     1620

tttggaagca tcaaatccga ctggctaggc tgc                                  1653


<210>  4043
<211>  1278
<212>  DNA
<213>  Homo Sapiens

<400>  4043
tatgccctga ctggacagaa gtggaggcaa aaacacatca cctacagcat tcacaactat       60

accccaaaag tgggtgagct agacacgcgg aaagctattc gccaggcttt cgatgtgtgg      120

cagaaggtga ccccactgac ctttgaagag gtgccatacc atgagatcaa aagtgaccgg      180

aaggaggcag acatcatgat cttttttgct tctggtttcc atggcgacag ctccccattt      240

gatggagaag ggggattcct ggcccatgcc tacttccctg gcccagggat tggaggagac      300

acccactttg actccgatga gccatggacg ctaggaaatg ccaaccatga cgggaacgac      360

ctcttcctgg tggctgtgca tgagctgggc cacgcgctgg gactggagca ctccagcgac      420

cccagcgcca tcatggcgcc cttctaccag tacatggaga cgcacaactt caagctgccc      480

caggacgatc tccagggcat ccagaagatc tatggacccc cagccgagcc tctggagccc      540

acaaggccac tccctacact ccccgtccgc aggatccact caccatcgga gaggaaacac      600

gagcgccagc ccaggccccc tcggccgccc ctcggggacc ggccatccac accaggcacc      660

aaacccaaca tctgtgacgg caacttcaac acagtggccc tcttccgggg cgagatgttt      720

gtctttaagg atcgctggtt ctggcgtctg cgcaataacc gagtgcagga gggctacccc      780

atgcagatcg agcagttctg gaagggcctg cctgcccgca tcgacgcagc ctatgaaagg      840

gccgatggga gatttgtctt cttcaaaggt gacaagtatt gggtgtttaa ggaggtgacg      900

gtggagcctg ggtaccccca cagcctgggg gagctgggca gctgtttgcc ccgtgaaggc      960

attgacacag ctctgcgctg ggaacctgtg ggcaagacct actttttcaa aggcgagcgg     1020

tactggcgct acagcgagga gcggcgggcc acggaccctg gctaccctaa gcccatcacc     1080

gtgtggaagg gcatcccaca ggctccccaa ggagccttca tcagcaagga aggatattac     1140

acctatttct acaagggccg ggactactgg aagtttgaca accagaaact gagcgtggag     1200

ccaggctacc cgcgcaacat cctgcgtgac tggatgggct gcaaccagaa ggaggtggag     1260

cggcggaagg agcggcgg                                                   1278


<210>  4044
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  4044
tttgcaaagc aaggtaacaa atggtacaag cagcacctct cctaccgcct ggtgaactgg       60

cctgagcatc tgccggagcc ggcagttcgg ggcgccgtgc gcgccgcctt ccagttgtgg      120

agcaacgtct cagcgctgga gttctgggag gccccagcca caggccccgc tgacatccgg      180

ctcaccttct tccaagggga ccacaacgat gggctgggca atgcctttga tggcccaggg      240

ggcgccctgg cgcacgcctt cctgccccgc cgcggcgaag cgcacttcga ccaagatgag      300

cgctggtccc tgagccgccg ccgcgggcgc aacctgttcg tggtgctggc gcacgagatc      360

ggtcacacgc ttggcctcac ccactcgccc gcgccgcgcg cgctcatggc gccctactac      420

aagaggctgg gccgcgacgc gctgctcagc tgggacgacg tgctggccgt gcagagcctg      480

tatgggaagc ccctaggggg ctcagtggcc gtccagctcc caggaaagct gttcactgac      540

tttgagacct gggactccta cagcccccaa ggaaggcgcc ctgaaacgca gggccctaaa      600

tactgccact cttccttcga tgccatcact gtagacaggc aacagcaact gtacattttt      660

aaagggagcc atttctggga ggtggcagct gatggcaacg tctcagagcc ccgtccactg      720

caggaaagat gggtcgggct gccccccaac attgaggctg cggcagtgtc attgaatgat      780

ggagatttct acttcttcaa agtgcaatcc gtt                                   813


<210>  4045
<211>  1803
<212>  DNA
<213>  Homo Sapiens

<400>  4045
ttccaaacct ttgagggcga cctcaagtgg caccaccaca acatcaccta ttggatccaa       60

aactactcgg aagacttgcc gcgggcggtg attgacgacg cctttgcccg cgccttcgca      120

ctgtggagcg cggtgacgcc gctcaccttc actcgcgtgt acagccggga cgcagacatc      180

gtcatccagt ttggtgtcgc ggagcacgga gacgggtatc ccttcgacgg gaaggacggg      240

ctcctggcac acgcctttcc tcctggcccc ggcattcagg gagacgccca tttcgacgat      300

gacgagttgt ggtccctggg caagggcgtc gtggttccaa ctcggtttgg aaacgcagat      360

ggcgcggcct gccacttccc cttcatcttc gagggccgct cctactctgc ctgcaccacc      420

gacggtcgct ccgacggctt gccctggtgc agtaccacgg ccaactacga caccgacgac      480

cggtttggct tctgccccag cgagagactc tacacccggg acggcaatgc tgatgggaaa      540

ccctgccagt ttccattcat cttccaaggc caatcctact ccgcctgcac cacggacggt      600

cgctccgacg gctaccgctg gtgcgccacc accgccaact acgaccggga caagctcttc      660

ggcttctgcc cgacccgagc tgactcgacg gtgatggggg gcaactcggc gggggagctg      720

tgcgtcttcc ccttcacttt cctgggtaag gagtactcga cctgtaccag cgagggccgc      780

ggagatgggc gcctctggtg cgctaccacc tcgaactttg acagcgacaa gaagtggggc      840

ttctgcccgg accaaggata cagtttgttc ctcgtggcgg cgcatgagtt cggccacgcg      900

ctgggcttag atcattcctc agtgccggag gcgctcatgt accctatgta ccgcttcact      960

gaggggcccc ccttgcataa ggacgacgtg aatggcatcc ggcacctcta tggtcctcgc     1020

cctgaacctg agccacggcc tccaaccacc accacaccgc agcccacggc tcccccgacg     1080

gtctgcccca ccggaccccc cactgtccac ccctcagagc gccccacagc tggccccaca     1140

ggtcccccct cagctggccc cacaggtccc cccactgctg gcccttctac ggccactact     1200

gtgcctttga gtccggtgga cgatgcctgc aacgtgaaca tcttcgacgc catcgcggag     1260

attgggaacc agctgtattt gttcaaggat gggaagtact ggcgattctc tgagggcagg     1320

gggagccggc cgcagggccc cttccttatc gccgacaagt ggcccgcgct gccccgcaag     1380

ctggactcgg tctttgagga gccgctctcc aagaagcttt tcttcttctc tgggcgccag     1440

gtgtgggtgt acacaggcgc gtcggtgctg ggcccgaggc gtctggacaa gctgggcctg     1500

ggagccgacg tggcccaggt gaccggggcc ctccggagtg gcagggggaa gatgctgctg     1560

ttcagcgggc ggcgcctctg gaggttcgac gtgaaggcgc agatggtgga tccccggagc     1620

gccagcgagg tggaccggat gttccccggg gtgcctttgg acacgcacga cgtcttccag     1680

taccgagaga aagcctattt ctgccaggac cgcttctact ggcgcgtgag ttcccggagt     1740

gagttgaacc aggtggacca agtgggctac gtgacctatg acatcctgca gtgccctgag     1800

gac                                                                   1803


<210>  4046
<211>  3627
<212>  DNA
<213>  Homo Sapiens

<400>  4046
cttaacaaca gtaagcattc ttggactata cctgaggatg ggaactctca gaagactatg       60

ccttctgctt cagttcctcc aaataaaata caaagtttgc aaatactgcc aaccactcgg      120

gtcatgtcgg cggagatagc tacaactcca gaggcaagaa cttctgaaga cagtcttctt      180

aaatcaacac tgcctccctc agaaacaagt gcacctgctg agggtgtgag aaatcaaact      240

ctcacatcca cagagaaagc agaaggagtg gtcaagttac agaatcttac cctcccaacc      300

aacgctagca tcaagttcaa tcctggagca gaatcagtgg tcctttccaa ttctacactg      360

aaatttcttc agagctttgc cagaaagtca aatgaacaag caacttctct aaacacagtt      420

ggaggcactg gaggcattgg aggcgttgga ggcactggag gcgtgggaaa tcgagcccca      480

cgggaaacat acctcagccg gggtgacagc agttccagcc aaagaactga ctaccaaaaa      540

tcaaatttcg aaacaactag aggaaagaat tggtgtgctt atgtacatac caggttatct      600

cccacagtga tattggacaa ccaggtcact tatgtcccag gtgggaaagg accttgtggc      660

tggaccggtg gatcctgtcc tcagagatct cagaagatat ccaatcctgt ctataggatg      720

caacataaaa ttgtcacctc attggattgg aggtgctgtc ctggatacag tgggccgaaa      780

tgtcaactaa gagcccagga acagcaaagt ttgatacaca ccaaccaggc tgaaagtcat      840

acagctgttg gcagaggagt agctgagcag cagcagcagc aaggctgtgg tgacccagaa      900

gtgatgcaaa aaatgactga tcaggtgaac taccaggcaa tgaaactgac tcttctgcag      960

aagaagattg acaatatttc tttgactgtg aatgatgtaa ggaacactta ctcctcccta     1020

gaaggaaaag tcagcgaaga taaaagcaga gaatttcaat ctcttctaaa aggtctaaaa     1080

tccaaaagca ttaatgtact gataagagac atagtaagag aacaatttaa aatttttcaa     1140

aatgacatgc aagagactgt agcacagctc ttcaagactg tatcaagtct atcagaggac     1200

ctcgaaagca ccaggcaaat aattcaaaaa gttaatgaat ctgtggtttc aatagcagcc     1260

cagcaaaagt ttgttttggt gcaagagaat cggcccactt tgactgatat agtggaacta     1320

aggaatcaca ttgtgaatgt aaggcaagaa atgactctta catgtgagaa gcctattaaa     1380

gaactagaag taaagcagac tcatttagaa ggtgctctag aacaggaaca ctcaagaagc     1440

attctgtatt atgaatccct caataaaact ctttctaaat tgaaggaagt acatgagcag     1500

cttttatcaa ctgaacaggt atcagaccag aagaatgctc cagctgctga gtcagttagc     1560

aataatgtca ctgagtacat gtctacttta catgaaaata taaagaagca gagtttgatg     1620

atgctgcaaa tgtttgaaga tttgcacatt caagaaagca agattaacaa tctcaccgtc     1680

tctttggaga tggagaaaga gtctctcaga ggtgaatgtg aagacatgtt atccaaatgc     1740

agaaatgatt ttaaatttca acttaaggac acagaagaga atttacatgt gttaaatcaa     1800

acattggctg aagttctctt tccaatggac aataagatgg acaaaatgag tgagcaacta     1860

aatgatttga cttatgatat ggagatcctt caacccttgc ttgagcaggg agcatcactc     1920

agacagacaa tgacatatga acaaccaaag gaagcaatag tgataaggaa aaagatagaa     1980

aatctgacta gtgctgtcaa tagtctaaat tttattatca aagaacttac aaaaagacac     2040

aacttactta gaaatgaagt acagggtcgt gatgatgcct tagaaagacg tatcaatgaa     2100

tatgccttag aaatggaaga tggcctcaat aagacaatga ctattataaa taatgctatt     2160

gatttcattc aagataacta tgccctaaaa gagactttaa gtactattaa ggataatagt     2220

gagatccatc ataaatgtac ctccgatatg gaaactattt tgacatttat tcctcagttc     2280

caccgtctga atgattctat tcagactttg gtcaatgaca atcagagata taactttgtt     2340

ttgcaagtcg ccaagaccct tgcaggtatt cccagagatg agaaactaaa tcagtccaac     2400

ttccaaaaga tgtatcaaat gttcaatgaa accacttccc aagtgagaaa ataccagcaa     2460

aatatgagtc atttggaaga aaaactactc ttaactacca agatttccaa aaattttgag     2520

actcggttgc aagacattga gtctaaagtt acccagacgc tcatacctta ttatatttca     2580

gttaaaaaag gcagtgtagt tacaaatgag agagatcagg ctcttcaact gcaagtatta     2640

aattccagat ttaaggcgtt ggaagcaaaa tctatccatc tttcaattaa cttcttttcg     2700

cttaacaaaa ctctccacga agttttaaca atgtgtcaca atgcttctac aagtgtgtca     2760

gaactgaatg ctaccatccc taagtggata aaacattccc tgccagatat tcaacttctt     2820

cagaaaggtc taagagaatt tgtggaacca ataattcaaa taaaaactca agctgcccta     2880

tctaatttaa cttgttgtat agatcgatcg ttgcctggta gtctggcaaa tgttgtcaag     2940

tctcagaagc aagtaaaatc attgccaaag aaaattaacg cacttaagaa accaacggta     3000

aatcttacca cagtcctgat aggccggact caaagaaaca cggacaacat aatatatcct     3060

gaggagtatt caagctgtag tcggcatccg tgccaaaatg ggggcacgtg cataaatgga     3120

agaactagct ttacctgtgc ctgcagacat ccttttactg gtgacaactg cactatcaag     3180

cttgtggaag aaaatgcttt agctccagat ttttccaaag gatcttacag atatgcaccc     3240

atggtggcat tttttgcatc tcatacgtat ggaatgacta tacctggtcc tatcctgttt     3300

aataacttgg atgtcaatta tggagcttca tataccccaa gaactggaaa atttagaatt     3360

ccgtatcttg gagtatatgt tttcaagtac accatcgagt catttagtgc tcatatttct     3420

ggatttttag tggttgatgg aatagacaag cttgcatttg agtctgaaaa tattaacagt     3480

gaaatacact gtgatagggt tttaactggg gatgccttat tagaattaaa ttatgggcag     3540

gaagtctggt tacgacttgc aaaaggaaca attccagcca agtttccccc tgttactaca     3600

tttagtggct atttattata tcgtaca                                         3627


<210>  4047
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  4047
gggcagttca gagtgatagg accaagacac cctatccggg ctctggtcgg ggatgaagtg       60

gaattgccat gtcgcatatc tcctgggaag aacgctacag gcatggaggt ggggtggtac      120

cgccccccct tctctagggt ggttcatctc tacagaaatg gcaaggacca agatggagac      180

caggcacctg aatatcgggg ccggacagag ctgctgaaag atgctattgg tgagggaaag      240

gtgactctca ggatccggaa tgtaaggttc tcagatgaag gaggtttcac ctgcttcttc      300

cgagatcatt cttaccaaga ggaggcagca atggaattga aagtagaaga tcctttctac      360

tgggtgagcc ctgga                                                       375


<210>  4048
<211>  1398
<212>  DNA
<213>  Homo Sapiens

<400>  4048
caagatgtct ccttgctggc atcagactca gagcccctga agtgtttctc ccgaacattt       60

gaggacctca cttgcttctg ggatgaggaa gaggcagcgc ccagtgggac ataccagctg      120

ctgtatgcct acccgcggga gaagccccgt gcttgccccc tgagttccca gagcatgccc      180

cactttggaa cccgatacgt gtgccagttt ccagaccagg aggaagtgcg tctcttcttt      240

ccgctgcacc tctgggtgaa gaatgtgttc ctaaaccaga ctcggactca gcgagtcctc      300

tttgtggaca gtgtaggcct gccggctccc cccagtatca tcaaggccat gggtgggagc      360

cagccagggg aacttcagat cagctgggag gagccagctc cagaaatcag tgatttcctg      420

aggtacgaac tccgctatgg ccccagagat cccaagaact ccactggtcc cacggtcata      480

cagctgattg ccacagaaac ctgctgccct gctctgcaga ggcctcactc agcctctgct      540

ctggaccagt ctccatgtgc tcagcccaca atgccctggc aagatggacc aaagcagacc      600

tccccaagta gagaagcttc agctctgaca gcagagggtg gaagctgcct catctcagga      660

ctccagcctg gcaactccta ctggctgcag ctgcgcagcg aacctgatgg gatctccctc      720

ggtggctcct ggggatcctg gtccctccct gtgactgtgg acctgcctgg agatgcagtg      780

gcacttggac tgcaatgctt taccttggac ctgaagaatg ttacctgtca atggcagcaa      840

caggaccatg ctagctccca aggcttcttc taccacagca gggcacggtg ctgccccaga      900

gacaggtacc ccatctggga gaactgcgaa gaggaagaga aaacaaatcc aggactacag      960

accccacagt tctctcgctg ccacttcaag tcacgaaatg acagcattat tcacatcctt     1020

gtggaggtga ccacagcccc gggtactgtt cacagctacc tgggctcccc tttctggatc     1080

caccaggctg tgcgcctccc caccccaaac ttgcactgga gggagatctc cagtgggcat     1140

ctggaattgg agtggcagca cccatcgtcc tgggcagccc aagagacctg ttatcaactc     1200

cgatacacag gagaaggcca tcaggactgg aaggtgctgg agccgcctct cggggcccga     1260

ggagggaccc tggagctgcg cccgcgatct cgctaccgtt tacagctgcg cgccaggctc     1320

aacggcccca cctaccaagg tccctggagc tcgtggtcgg acccaactag ggtggagacc     1380

gccaccgaga ccgcctgg                                                   1398


<210>  4049
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  4049
atcgtggttt acaccgacag ggaggtccat ggtgctgtgg gctcccgggt gaccctgcac       60

tgctccttct ggtccagtga gtgggtctca gatgacatct ccttcacctg gcgctaccag      120

cccgaagggg gcagagatgc catttcgatc ttccactatg ccaagggaca accctacatt      180

gacgaggtgg ggaccttcaa agagcgcatc cagtgggtag gggaccctcg ctggaaggat      240

ggctccattg tcatacacaa cctagactac agtgacaatg gcacgttcac ttgtgacgtc      300

aaaaaccctc cagacatagt gggcaagacc tctcaggtca cgctgtatgt ctttgaaaaa      360

gtgccaacta gg                                                          372


<210>  4050
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  4050
tcagccttgg aagtatatac gccaaaagaa atcttcgtgg caaatggtac acaagggaag       60

ctgacctgca agttcaagtc tactagtacg actggcgggt tgacctcagt ctcctggagc      120

ttccagccag agggggccga cactactgtg tcgtttttcc actactccca agggcaagtg      180

taccttggga attatccacc atttaaagac agaatcagct gggctggaga ccttgacaag      240

aaagatgcat caatcaacat agaaaatatg cagtttatac acaatggcac ctatatctgt      300

gatgtcaaaa accctcctga catcgttgtc cagcctggac acattaggct ctatgtcgta      360

gaaaaagaga atttgcctgt g                                                381


<210>  4051
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  4051
gtggaaattt atacctcccg ggtgctggag gctgttaatg ggacagatgc tcggttaaaa       60

tgcactttct ccagctttgc ccctgtgggt gatgctctaa cagtgacctg gaattttcgt      120

cctctagacg ggggacctga gcagtttgta ttctactacc acatagatcc cttccaaccc      180

atgagtgggc ggtttaagga ccgggtgtct tgggatggga atcctgagcg gtacgatgcc      240

tccatccttc tctggaaact gcagttcgac gacaatggga catacacctg ccaggtgaag      300

aacccacctg atgttgatgg ggtgataggg gagatccggc tcagcgtcgt gcacactgta      360

cgcttctctg agatccactt cctg                                             384


<210>  4052
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  4052
ttggagattc gtgcagatgc ccatgtccga ggttatgttg gagaaaagat caagttgaaa       60

tgcactttca agtcaacttc agatgtcact gacaaactta ctatagactg gacatatcgc      120

cctcccagca gcagccacac agtatcaata tttcattatc agtctttcca gtacccaacc      180

acagcaggca catttcggga tcggatttcc tgggttggaa atgtatacaa aggggatgca      240

tctataagta taagcaaccc taccataaag gacaatggga cattcagctg tgctgtgaag      300

aatcccccag atgtgcatca taatattccc atgacagagc taacagtcac agaaaggggt      360

tttggcacca tgctttcctc t                                                381


<210>  4053
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4053
cggacgcact ctctgagata ttttcgcctg ggcgtttcgg atcccatcca tggggtccct       60

gaatttattt cggttgggta cgtggactcg caccctatca ccacatatga cagtgtcact      120

cggcagaagg agccacgggc cccatggatg gcagagaacc tcgcgcctga tcactgggag      180

aggtacactc agctgctgag gggctggcag cagatgttca aggtggaact gaagcgccta      240

cagaggcact acaatcactc agataatgtg gctcacacca tcaagcaggc atgggaggcc      300

aatcagcatg agttgctgta tcaaaagaat tggctggaag aagaatgtat tgcctggcta      360

aagagattcc tggagtatgg gaaagacacc ctacaaagaa cagagccccc actggtcaga      420

gtaaatcgca aagaaacttt tccaggggtt acagctctct tctgcaaagc tcatggcttt      480

taccccccag aaatttacat gacatggatg aaaaacgggg aagaaattgt ccaagaaatt      540

gattatggag acattcttcc cagtggggat ggaacctatc aggcgtgggc atcaattgag      600

cttgatcctc agagcagcaa cctttactcc tgtcatgtgg agcactgcgg tgtccacatg      660

gttcttcagg tcccccagga atcagaaact atccctcttg tgatg                      705


<210>  4054
<211>  1440
<212>  DNA
<213>  Homo Sapiens

<400>  4054
ctactggaca ccaggcaatt tttaatctat aatgaagatc acaagcgctg cgtggatgca       60

gtgagtccca gtgccgtcca aaccgcagct tgcaaccagg atgccgaatc acagaaattc      120

cgatgggtgt ccgaatctca gattatgagt gttgcattta aattatgcct gggagtgcca      180

tcaaaaacgg actgggttgc tatcactctc tatgcctgtg actcaaaaag tgaatttcag      240

aaatgggagt gcaaaaatga cacacttttg gggatcaaag gagaagattt attttttaac      300

tacggcaaca gacaagaaaa gaatattatg ctctacaagg gatcgggttt atggagcagg      360

tggaagatct atggaaccac agacaatctg tgctccagag gttatgaagc catgtatacg      420

ctactaggca atgccaatgg agcaacctgt gcattcccgt tcaagtttga aaacaagtgg      480

tacgcagatt gcacgagtgc tgggcggtcg gatggatggc tctggtgcgg aaccactact      540

gactatgaca cagacaagct atttggatat tgtccattga aatttgaggg cagtgaaagc      600

ttatggaata aagacccgct gaccagcgtt tcctaccaga taaactccaa atccgcttta      660

acgtggcacc aggcgaggaa aagctgccaa caacagaacg ctgagctcct gagcatcaca      720

gagattcatg agcaaacata cctgacagga ttaaccagtt ccttgacctc aggactctgg      780

attggactta acagtctgag cttcaacagc ggttggcagt ggagtgaccg cagtcctttc      840

cgatatttga actggttacc aggaagtcca tcagctgaac ctggaaaaag ctgtgtgtca      900

ctaaatcctg gaaaaaatgc taaatgggaa aatctggaat gtgttcagaa actgggctat      960

atttgcaaaa agggcaacac cactttaaat tcttttgtta ttccctcaga aagtgatgtg     1020

cctactcact gtcctagtca gtggtggccg tatgccggtc actgttacaa gattcacaga     1080

gatgagaaaa aaatccagag ggatgctctg accacctgca ggaaggaagg cagtgacctc     1140

gcaagtatcc acaccattga ggaattcgac tttattatct cccagctagg atatgagcca     1200

aatgacgaat tgtggatcgg cttaaatgac attaagattc aaatgtactt tgagtggagt     1260

gatgggaccc ctgtaacgtt taccaaatgg cttcgtggag aaccaagcca tgaaaacaac     1320

agacaggagg attgtgtggt gatgaaaggc aaggctggag tgcaatggca caatcttggc     1380

tcaatgcaac ctctgcctcg agagttcaag cgattctcct gcctcagcct cccgagtagc     1440


<210>  4055
<211>  4152
<212>  DNA
<213>  Homo Sapiens

<400>  4055
ggcgcccctg gggacgccgc cctcccggaa cccaacgtct tcctcatctt cagccatgga       60

ctgcagggct gcctggaggc ccagggcggg caggtcagag tcaccccggc ttgcaatacc      120

agcctccctg cccagcgctg gaagtgggtc tcccgaaacc ggctattcaa cctgggtacc      180

atgcagtgcc tgggcacagg ctggccaggc accaacacca cggcctccct gggcatgtat      240

gagtgtgacc gggaagcact gaatcttcgc tggcattgtc gtacactggg tgaccagctg      300

tccttgctcc tgggggcccg caccagcaac atatccaagc ctggcaccct tgagcgtggt      360

gaccagaccc gcagtggcca gtggcgcatc tacggcagcg aggaggacct atgtgctctg      420

ccctaccacg aggtctacac catccaggga aactcccacg gaaagccgtg caccatcccc      480

ttcaaatatg acaaccagtg gttccacggc tgcaccagca cgggccgcga ggatggtcac      540

ctgtggtgtg ccaccaccca ggactacggc aaagacgagc gctggggctt ctgccccatc      600

aagagtaacg actgcgagac cttctgggac aaggaccagc tgactgacag ctgctaccag      660

tttaacttcc agtccacgct gtcgtggagg gaggcctggg ccagctgcga gcagcagggt      720

gcggatctgc tgagcatcac ggagatccac gagcagacct acatcaacgg cctcctcact      780

gggtacagct ccaccctgtg gatcggcttg aatgacttgg acacgagcgg aggctggcag      840

tggtcggaca actcgcccct caagtacctc aactgggaga gtgaccagcc ggacaacccc      900

agtgaggaga actgtggagt gatccgcact gagtcctcgg gcggctggca gaaccgtgac      960

tgcagcatcg cgctgcccta tgtgtgcaag aagaagccca acgccacggc cgagcccacc     1020

cctccagaca ggtgggccaa tgtgaaggtg gagtgcgagc cgagctggca gcccttccag     1080

ggccactgct accgcctgca ggccgagaag cgcagctggc aggagtccaa gaaggcatgt     1140

ctacggggcg gtggcgacct ggtcagcatc cacagcatgg cggagctgga attcatcacc     1200

aagcagatca agcaagaggt ggaggagctg tggatcggcc tcaacgattt gaaactgcag     1260

atgaattttg agtggtctga cgggagcctt gtgagcttca cccactggca cccctttgag     1320

cccaacaact tccgggacag tctggaggac tgtgtcacca tctggggccc ggaaggccgc     1380

tggaacgaca gtccctgtaa ccagtccttg ccatccatct gcaagaaggc aggccagctg     1440

agccaggggg ccgccgagga ggaccatggc tgccggaagg gttggacgtg gcacagccca     1500

tcctgctact ggctgggaga agaccaagtg acctacagtg aggcccggcg cctgtgcact     1560

gaccatggct ctcagctggt caccatcacc aacaggttcg agcaggcctt cgtcagcagc     1620

ctcatctaca actgggaggg cgagtacttc tggacggccc tgcaggacct caacagcacc     1680

ggctccttct tctggctcag tggggatgaa gtcatgtaca cccactggaa ccgggaccag     1740

cccgggtaca gccgtggggg ctgcgtggcg ctggccactg gcagcgccat ggggctgtgg     1800

gaggtgaaga actgtacctc gttccgggcc cgctacatct gccggcagag cctgggcact     1860

ccagtgacgc cggagctgcc ggggccagat cccacgccca gcctcactgg ctcctgtccc     1920

cagggctggg cctcggacac caaactccgg tattgctata aggtgttcag ctcagagcgg     1980

ctgcaggaca agaagagctg ggtccaggcc cagggggcct gccaggagct gggggcccag     2040

ctgctgagcc tggccagcta cgaggaggag cactttgtgg ccaacatgct caacaagatc     2100

ttcggtgaat cagaacccga gatccacgag cagcactggt tctggatcgg cctgaaccgt     2160

cgggatccca gagggggtca gagttggcgc tggagcgacg gcgtagggtt ctcttaccac     2220

aatttcgacc ggagccggca cgacgacgac gacatccgag gctgtgcggt gctggacctg     2280

gcctccctgc agtgggtggc catgcagtgc gacacacagc tggactggat ctgcaagatc     2340

cccagaggta cggacgtgcg ggagcccgac gacagccctc aaggccgacg ggaatggctg     2400

cgcttccagg aggccgagta caagttcttt gagcaccact ccacgtgggc gcaggcgcag     2460

cgcatctgca cgtggttcca ggccgagctg acctccgtgc acagccaggc ggagctagac     2520

ttcctgagcc acaacttgca gaagttctcc cgggcccagg agcagcactg gtggatcggc     2580

ctgcacacct ctgagagcga tgggcgcttc agatggacag atggttccat tataaacttc     2640

atctcctggg caccaggcaa acctcggcct gtcggcaagg acaagaagtg cgtgtacatg     2700

acagccagcc gagaggactg gggggaccag aggtgcctga cagccttgcc ctacatctgc     2760

aagcgcagca acgtcaccaa agaaacgcag cccccagacc tgccaactac agccctgggg     2820

ggctgcccct ctgactggat ccagttcctc aacaagtgtt ttcaggtcca gggccaggaa     2880

ccccagagcc gggtgaagtg gtcagaggca cagttctcct gtgaacagca agaggcccag     2940

ctggtcacca tcacaaaccc cttagagcaa gcattcatca cagccagcct gcccaatgtg     3000

acctttgacc tttggattgg cctccatgcc tcgcagaggg acttccagtg ggtggagcag     3060

gagcctttga tgtatgccaa ctgggcacct ggggagccct ctggccctag ccctgctccc     3120

agtggcaaca aaccgaccag ctgtgcggtg gtcctgcaca gcccctcagc ccacttcact     3180

ggccgctggg acgatcggag ctgcacggag gagacccatg gcttcatctg ccagaagggc     3240

acggacccct ccctgagccc gtccccagca gcgctgcccc ccgccccggg cactgagctc     3300

tcctacctca acggcacctt ccggctgctt cagaagccgc tgcgctggca cgatgccctc     3360

ctgctgtgtg agagccacaa tgccagcctg gcctacgtgc ccgaccccta cacccaggcc     3420

ttcctcacgc aggctgcccg agggctgcgc acgccgctct ggattgggct ggctggcgag     3480

gagggctctc ggcggtactc ctgggtctca gaggagccgc tgaactacgt gggctggcag     3540

gacggggagc cgcagcagcc ggggggctgt acctacgtag atgtggacgg ggcctggcgc     3600

accaccagct gtgacaccaa gctgcagggg gctgtgtgtg gggttagcag tgggccccct     3660

cctccccgaa gaataagcta ccatggcagc tgtccccagg gactggcaga ctccgcgtgg     3720

attcccttcc gggagcactg ctattctttc cacatggagc tgctgctggg ccacaaggag     3780

gcgcgacagc gctgccagag agcgggtggg gccgtcctgt ctatcctgga tgagatggag     3840

aatgtgtttg tctgggagca cctgcagagc tatgagggcc agagtcgggg cgcctggctg     3900

ggcatgaact tcaaccccaa aggaggcact ctggtctggc aggacaacac agctgtgaac     3960

tactccaact gggggccccc gggcttgggc cccagcatgc tgagccacaa cagctgctac     4020

tggattcaga gcaacagcgg gctatggcgc cccggcgctt gcaccaacat caccatgggt     4080

gtcgtctgca agcttcctcg tgctgagcag agcagcttct ccccatcagc gcttccagag     4140

aacccagcgg cc                                                         4152


<210>  4056
<211>  1125
<212>  DNA
<213>  Homo Sapiens

<400>  4056
aagtgggaaa cgaagaattg ctcagttagt tcaactaatg caaatgatat aactcaaagt       60

ctcacgggaa aaggaaatga cagcgaagag gaaatgagat ttcaagaagt ctttatggaa      120

cacatgagca acatggagaa gagaatccag catattttag acatggaagc caacctcatg      180

gacacagagc atttccaaaa tttcagcatg acaactgatc aaagatttaa tgacattctt      240

ctgcagctaa gtaccttgtt ttcctcagtc cagggacatg ggaatgcaat agatgaaatc      300

tccaagtcct taataagttt gaataccaca ttgcttgatt tgcagctcaa catagaaaat      360

ctgaatggca aaatccaaga gaataccttc aaacaacaag aggaaatcag taaattagag      420

gagcgtgttt acaatgtatc agcagaaatt atggctatga aagaagaaca agtgcatttg      480

gaacaggaaa taaaaggaga agtgaaagta ctgaataaca tcactaatga tctcagactg      540

aaagattggg aacattctca gaccttgaga aatatcactt taattcaagg tcctcctgga      600

cccccgggtg aaaaaggaga tcgaggtccc actggagaaa gtggtccacg aggatttcca      660

ggtccaatag gtcctccggg tcttaaaggt gatcggggag caattggctt tcctggaagt      720

cgaggactcc caggatatgc cggaaggcca ggaaattctg gaccaaaagg ccagaaaggg      780

gaaaagggga gtggaaacac attaactcca tttacgaaag ttcgactggt cggtgggagc      840

ggccctcacg aggggagagt ggagatactc cacagcggcc agtggggtac aatttgtgac      900

gatcgctggg aagtgcgcgt tggacaggtc gtctgtagga gcttgggata cccaggtgtt      960

caagccgtgc acaaggcagc tcactttgga caaggtactg gtccaatatg gctgaatgaa     1020

gtgttttgtt ttgggagaga atcatctatt gaagaatgta aaattcggca atgggggaca     1080

agagcctgtt cacattctga agatgctgga gtcacttgca cttta                     1125


<210>  4057
<211>  2079
<212>  DNA
<213>  Homo Sapiens

<400>  4057
cagcgctcgc cattgaatga cttccaagtg ctccggggca cagagctaca gcacctgcta       60

catgcggtgg tgcccgggcc ttggcaggag gatgtggcag atgctgaaga gtgtgctggt      120

cgctgtgggc ccttaatgga ctgccgggcc ttccactaca acgtgagcag ccatggttgc      180

caactgctgc catggactca acactcgccc cacacgaggc tgcggcgttc tgggcgctgt      240

gacctcttcc agaagaaaga ctacgtacgg acctgcatca tgaacaatgg ggttgggtac      300

cggggcacca tggccacgac cgtgggtggc ctgccctgcc aggcttggag ccacaagttc      360

ccgaatgatc acaagtacac gcccactctc cggaatggcc tggaagagaa cttctgccgt      420

aaccctgatg gcgaccccgg aggtccttgg tgctacacaa cagaccctgc tgtgcgcttc      480

cagagctgcg gcatcaaatc ctgccgggag gccgcgtgtg tctggtgcaa tggcgaggaa      540

taccgcggcg cggtagaccg cacggagtca gggcgcgagt gccagcgctg ggatcttcag      600

cacccgcacc agcacccctt cgagccgggc aagttcctcg accaaggtct ggacgacaac      660

tattgccgga atcctgacgg ctccgagcgg ccatggtgct acactacgga tccgcagatc      720

gagcgagagt tctgtgacct cccccgctgc gggtccgagg cacagccccg ccaagaggcc      780

acaactgtca gctgcttccg cgggaagggt gagggctacc ggggcacagc caataccacc      840

actgcgggcg taccttgcca gcgttgggac gcgcaaatcc ctcatcagca ccgatttacg      900

ccagaaaaat acgcgtgcaa agaccttcgg gagaacttct gccggaaccc cgacggctca      960

gaggcgccct ggtgcttcac actgcggccc ggcatgcgcg cggccttttg ctaccagatc     1020

cggcgttgta cagacgacgt gcggccccag gactgctacc acggcgcagg ggagcagtac     1080

cgcggcacgg tcagcaagac ccgcaagggt gtccagtgcc agcgctggtc cgctgagacg     1140

ccgcacaagc cgcagttcac gtttacctcc gaaccgcatg cacaactgga ggagaacttc     1200

tgccggaacc cagatgggga tagccatggg ccctggtgct acacgatgga cccaaggacc     1260

ccattcgact actgtgccct gcgacgctgc gctgatgacc agccgccatc aatcctggac     1320

cccccagacc aggtgcagtt tgagaagtgt ggcaagaggg tggatcggct ggatcagcgg     1380

cgttccaagc tgcgcgtggt tgggggccat ccgggcaact caccctggac agtcagcttg     1440

cggaatcggc agggccagca tttctgcggg gggtctctag tgaaggagca gtggatactg     1500

actgcccggc agtgcttctc ctcctgccat atgcctctca cgggctatga ggtatggttg     1560

ggcaccctgt tccagaaccc acagcatgga gagccaagcc tacagcgggt cccagtagcc     1620

aagatggtgt gtgggccctc aggctcccag cttgtcctgc tcaagctgga gagatctgtg     1680

accctgaacc agcgtgtggc cctgatctgc ctgccccctg aatggtatgt ggtgcctcca     1740

gggaccaagt gtgagattgc aggctggggt gagaccaaag gtacgggtaa tgacacagtc     1800

ctaaatgtgg ccttgctgaa tgtcatctct aaccaggagt gtaacatcaa gcaccgagga     1860

cgtgtgcggg agagtgagat gtgcactgag ggactgttgg cccctgtggg ggcctgtgag     1920

ggtgactacg ggggcccact tgcctgcttt acccacaact gctgggtcct ggaaggaatt     1980

ataatcccca accgagtatg cgcaaggtcc cgctggccag ctgtcttcac gcgtgtctct     2040

gtgtttgtgg actggattca caaggtcatg agactgggt                            2079


<210>  4058
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  4058
cctaaacccg caacagttgt tacgggttct ggtcatgcaa gctctacccc aggtggagaa       60

aaggagactt cggctaccca gagaagttca gtgcccagct ctactgagaa gaatgctttt      120

aattcctctc tggaagatcc cagcaccgac tactaccaag agctgcagag agacatttct      180

gaaatgtttt tgcagattta taaacaaggg ggttttctgg gcctctccaa tattaagttc      240

aggccaggat ctgtggtggt acaattgact ctggccttcc gagaaggtac catcaatgtc      300

cacgacgtgg agacacagtt caatcagtat aaaacggaag cagcctctcg atataacctg      360

acgatctcag acgtcagcgt gagtgatgtg ccatttcctt tctctgccca gtctggggct      420

ggggtgccag gc                                                          432


<210>  4059
<211>  1209
<212>  DNA
<213>  Homo Sapiens

<400>  4059
acaaaccaag gcaactctgc cgatgctgtg actactaccg agacagccac ctctggaccg       60

actgtagctg cagccgacac gaccgagaca aattttcctg agacagccag cactactgca      120

aacaccccgt ctttccctac ggcaacgagt ccagcgccac caataatcag cacgcacagc      180

tcatctacaa tccctacccc ggcgcctccc ataataagca ctcattccag tagcacgatt      240

ccgataccca ctgctgcaga ttctgaatcc accacgaatg tcaacagttt ggctaccagc      300

gacatcatca cagctagtag tccgaatgac ggtctgatta cgatggtgcc ttcagagact      360

caaagtaaca acgagatgtc acccactaca gaagataatc agtccagcgg ccctccaaca      420

ggcaccgcgt tactagagac gtcaactttg aatagtaccg gccccagcaa tccgtgtcaa      480

gatgatccct gcgccgacaa ttcattatgt gttaaattac ataatacgag cttttgtttg      540

tgcttggagg gttattacta caactcaagt acatgcaaaa agggtaaggt gtttcccggg      600

aaaatatctg ttactgtttc cgagactttc gatccagaag aaaagcattc catggcatat      660

caggacctgc acagtgaaat taccagcctt ttcaaagacg tattcggtac gtccgtgtat      720

ggtcaaaccg tgatattaac agtgagcacg tctttatctc ccagaagtga gatgagggcg      780

gatgacaagt tcgtaaacgt aacgatagta acaattctag ctgaaaccac gtctgataat      840

gagaaaacgg ttaccgagaa aatcaacaag gcaataagat cttcttcatc caattttttg      900

aactatgatt taacattgcg ttgcgactat tacggctgta atcagacggc ggacgactgt      960

ttgaacggac tagcttgcga ttgtaagagc gatctgcagc gtcccaaccc gcagagtccc     1020

ttctgtgtcg cttctagctt gaagtgtcct gatgcgtgta atgcgcagca taagcaatgc     1080

ctgataaaga agtcaggggg cgcacctgaa tgtgcatgcg tcccaggcta tcaagaagat     1140

gccaatggta actgccaaaa gtgcgctttc ggatattcag gacttgattg taaggacaaa     1200

tttcagcta                                                             1209


<210>  4060
<211>  2193
<212>  DNA
<213>  Homo Sapiens

<400>  4060
agcacacctg tgatcacttc tacccaagtc agttcatctc ctgtgactcc tgaaggtacc       60

accatgccaa tctggacgcc tagtgaagga agcactccat taacaactat gcctgtcagc      120

accacacgtg tgaccagctc tgagggtagc accctttcaa caccttctgt tgtcaccagc      180

acacctgtga ccacttctac tgaagccatt tcatcttctg caactcttga cagcaccacc      240

atgtctgtgt caatgcccat ggaaataagc acccttggga ccactattct tgtcagtacc      300

acacctgtta cgaggtttcc tgagagtagc accccttcca taccatctgt ttacaccagc      360

atgtctatga ccactgcctc tgaaggcagt tcatctccta caactcttga aggcaccacc      420

accatgccta tgtcaactac gagtgaaaga agcactttat tgacaactgt cctcatcagc      480

cctatatctg tgatgagtcc ttctgaggcc agcacacttt caacacctcc tggtgatacc      540

agcacacctt tgctcacctc taccaaagcc ggttcattct ccatacctgc tgaagtcact      600

accatacgta tttcaattac cagtgaaaga agcactccat taacaactct ccttgtcagc      660

accacacttc caactagctt tcctggggcc agcatagctt cgacacctcc tcttgacaca      720

agcacaactt ttaccccttc tactgacact gcctcaactc ccacaattcc tgtagccacc      780

accatatctg tatcagtgat cacagaagga agcacacctg ggacaaccat ttttattccc      840

agcactcctg tcaccagttc tactgctgat gtctttcctg caacaactgg tgctgtatct      900

acccctgtga taacttccac tgaactaaac acaccatcaa cctccagtag tagtaccacc      960

acatcttttt caactactaa ggaatttaca acacccgcaa tgactactgc agctcccctc     1020

acatatgtga ccatgtctac tgcccccagc acacccagaa caaccagcag aggctgcact     1080

acttctgcat caacgctttc tgcaaccagt acacctcaca cctctacttc tgtcaccacc     1140

cgtcctgtga ccccttcatc agaatccagc aggccgtcaa caattacttc tcacaccatc     1200

ccacctacat ttcctcctgc tcactccagt acacctccaa caacctctgc ctcctccacg     1260

actgtgaacc ctgaggctgt caccaccatg accaccagga caaaacccag cacacggacc     1320

acttccttcc ccacggtgac caccaccgct gtccccacga atactacaat taagagcaac     1380

cccacctcaa ctcctactgt gccaagaacc acaacatgct ttggagatgg gtgccagaat     1440

acggcctctc gctgcaagaa tggaggcacc tgggatgggc tcaagtgcca gtgtcccaac     1500

ctctattatg gggagttgtg tgaggaggtg gtcagcagca ttgacatagg gccaccggag     1560

actatctctg cccaaatgga actgactgtg acagtgacca gtgtgaagtt caccgaagag     1620

ctaaaaaacc actcttccca ggaattccag gagttcaaac agacattcac ggaacagatg     1680

aatattgtgt attccgggat ccctgagtat gtcggggtga acatcacaaa gctacgtctt     1740

ggcagtgtgg tggtggagca tgacgtcctc ctaagaacca agtacacacc agaatacaag     1800

acagtattgg acaatgccac cgaagtagtg aaagagaaaa tcacaaaagt gaccacacag     1860

caaataatga ttaatgatat ttgctcagac atgatgtgtt tcaacaccac tggcacccaa     1920

gtgcaaaaca ttacggtgac ccagtacgac cctgaagagg actgccggaa gatggccaag     1980

gaatatggag actacttcgt agtggagtac cgggaccaga agccatactg catcagcccc     2040

tgtgagcctg gcttcagtgt ctccaagaac tgtaacctcg gcaagtgcca gatgtctcta     2100

agtggacctc agtgcctctg cgtgaccacg gaaactcact ggtacagtgg ggagacctgt     2160

aaccagggca cccagaagag tctggtgtac ggc                                  2193


<210>  4061
<211>  1590
<212>  DNA
<213>  Homo Sapiens

<400>  4061
ggccccagca cccgcagagc agacactgcg atgacaacgg acgacacaga agtgcccgct       60

atgactctag caccgggcca cgccgctctg gaaactcaaa cactgagcgc tgagacctct      120

tctagggcct caaccccagc cggccccgtt ccagaagcag agaccagggg agccaagaga      180

atttcccctg caagagagac caggagtttc acaaaaacat ctcccaactt catggtgctg      240

atcgccacct ccgtggagac atcagccgcc agtggcagcc ccgagggagc tggaatgacc      300

acagttcaga ccatcacagg cagtgatccc gaggaagcca tctttgacac cctttgcacc      360

gatgacagct ctgaagaggc aaagacactc acaatggaca tattgacatt ggctcacacc      420

tccacagaag ctaagggcct gtcctcagag agcagtgcct cttccgacgg cccccatcca      480

gtcatcaccc cgtcacgggc ctcagagagc agcgcctctt ccgacggccc ccatccagtc      540

atcaccccgt cacgggcctc agagagcagc gcctcttccg acggccccca tccagtcatc      600

accccgtcac gggcctcaga gagcagcgcc tcttccgacg gcccccatcc agtcatcacc      660

ccctcatggt ccccgggatc tgacgtcact ctcctcgctg aagccctggt gactgtcaca      720

aacatcgagg ttattaattg cagcatcaca gaaatagaaa caacgacttc cagcatccct      780

ggggcctcag acacagatcc catccccacg gaaggggtga aggcctcgtc cacctccgat      840

ccaccagctc tgcctgactc cactgaagca aaaccacaca tcactgaggt cacagcctct      900

gccgagaccc tgtccacagc cggcaccaca gagtcagctg cacctgatgc cacgattggg      960

accccactcc ccaccaacag caccatagaa agagaagtga cagcacccgg ggccacgacc     1020

ctcagtggag ctctggccac agggaatccc ctggaagaaa cctcagccct ctctgttgag     1080

acaccaagtt acgtcaaagt ctcaggagca gctccggtct ccatagaggc tgggtcagca     1140

gtgggcaaaa caacttcctt tgctgggagc tctgcttcct cctacagccc ctcggaagcc     1200

gccctcaaga acttcacccc ttcagagaca ctgaccacgg acatcgcaac caaggggccc     1260

ttccccacca gcagggaccc tcttccttct gtccctccaa ctacaaccaa cagcagccga     1320

gggacgaaca gcaccttagc caagatcaca acctcagcga agaccacgat gaagccccca     1380

acagccacgc ccacgactgc ccggacgagg ccgaccacag acatgagtgc aggtgaaaat     1440

ggaggtttcc tcctcctgcg gctgagtgtg gcttctccgg aagacctcac tgaccccaga     1500

gtggcagaaa ggctgatgca gcagctccac cgggaactcc acgcccacgc gcctcacttc     1560

caggtctcct tactgcgtgt caggagaggc                                      1590


<210>  4062
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  4062
aatgagacta gcacctctgc caacactgga tccagtgtga tctccagtgg agccagcaca       60

gccaccaact ctgggtccag tgtgacctcc agtggggtca gcacagccac catctcaggg      120

tccagcgtga cctccaatgg ggtcagcata gtcaccaact ctgagttcca tacaacctcc      180

agtgggatca gcacagccac caactctgag ttcagcacag cgtccagtgg gatcagcata      240

gccaccaact ctgagtccag cacaacctcc agtggggcca gcacagccac caactctgag      300

tccagcacac cctccagtgg ggccagcaca gccaccaact ctgactccag cacaacctcc      360

agtggggcta gcacagccac caactctgac tccagcacaa cctccagtga ggccagcaca      420

gccaccaact ctgagtccag cacaacctcc agtggggcca gcacagccac caactctgag      480

tccagcacga cctccagtgg ggccagcaca gccaccaact ctgagtccag cacaacctcc      540

agtggggcca gcacagccac caactctggg tccagcacga cctccagtgg gaccagcaca      600

gccaccaact ctgagtccag cacagtgtcc agtggggcca gcacagccac cacctctgag      660

tccagcacga cctccagtgg ggccagcaca gccaccaact ctgagtccag cacagtgtcc      720

agtggggcca gcactgccac caattctgag tccagcacaa cctccagtgg ggccaacaca      780

gccaccaact ctgggtccag tgtgacctct gcaggctctg gaacagcagc tctgactgga      840

atgcacacaa cttcccatag tgcatctact gcagtgagtg aggcgaagcc tggtgggtcc      900

ctggtgccgt gggaa                                                       915


<210>  4063
<211>  1137
<212>  DNA
<213>  Homo Sapiens

<400>  4063
cccaggtgtc tggggcccca cggagagcca gtgaaggtgg gccacaccgt cggcatggac       60

tgccaggagt gcacgtgtga ggcggccacg tggacgctga cctgccgacc caagctctgc      120

ccgctgcccc ctgcctgccc cctgcccggc ttcgtgcctg tgcctgcagc cccacaggcc      180

ggccagtgct gcccccagta cagctgcgcc tgcaacacca gccgctgccc cgcgcccgtg      240

ggctgtcctg agggcgcccg cgcgatcccg acctaccagg agggggcctg ctgcccagtc      300

caaaactgca gctggacagt gtgcagcatc aacgggaccc tgtaccagcc cggcgccgtg      360

gtctcctcga gcctgtgcga aacctgcagg tgtgagctgc cgggtggccc cccatcggac      420

gcgtttgtgg tcagctgtga gacccagatc tgcaacacac actgccctgt gggcttcgag      480

taccaggagc agagcgggca gtgctgtggc acctgtgtgc aggtcgcctg tgtcaccaac      540

accagcaaga gccccgccca cctcttctac cccggcgaga cctggtcaga cgcagggaac      600

cactgtgtga cccaccagtg tgagaagcac caggatgggc tcgtggtggt caccacgaag      660

aaggcgtgcc ccccgctcag ctgttctctg gacgaggccc gcatgagcaa ggacggctgc      720

tgccgcttct gcccgccgcc cccgcccccg taccagaacc agtcgacctg tgctgtgtac      780

cataggagcc tgatcatcca gcagcagggc tgcagctcct cggagcccgt gcgcctggct      840

tactgccggg ggaactgtgg ggacagctct tccatgtact cgctcgaggg caacacggtg      900

gagcacaggt gccagtgctg ccaggagctg cggacctcgc tgaggaatgt gaccctgcac      960

tgcaccgacg gctccagccg ggccttcagc tacaccgagg tggaagagtg cggctgcatg     1020

ggccggcggt gccctgcgcc gggcgacacc cagcactcgg aggaggcgga acccgagccc     1080

agccaggagg cagagagtgg gagctgggag agaggcgtcc cagtgtcccc catgcac        1137


<210>  4064
<211>  1158
<212>  DNA
<213>  Homo Sapiens

<400>  4064
cttccaaaag ctcctgtcat caccactcct cttgaaacag tggatgcctt agttgaagaa       60

gtggctactt tcatgtgtgc agtggaatcc tacccccagc ctgagatttc ctggactaga      120

aataaaattc tcattaaact ctttgacacc cggtacagca tccgggagaa tgggcagctc      180

ctcaccatcc tgagtgtgga agacagtgat gatggcattt actgctgcac ggccaacaat      240

ggtgtgggag gagctgtgga gagttgtgga gccctgcaag tgaagatgaa acctaaaata      300

actcgtcctc ccataaatgt gaaaataata gaaggattaa aagcagtcct accatgtact      360

acaatgggta atcccaaacc atcagtgtct tggataaagg gagacagccc tctcagggaa      420

aattcccgaa ttgcagttct tgaatctggg agcttgagga ttcataacgt acaaaaggaa      480

gatgcaggac agtatcgatg tgtggcaaaa aacagcctcg ggacagcata ttccaaagtg      540

gtgaagctgg aagttgagga agaaagtgaa cccgaacaag atactaaagt ttttgccagg      600

atcctgcggg ctcctgaatc ccacaatgtc acctttggct cctttgtgac cctgcactgt      660

acagcaacag gcattcctgt ccccaccatc acctggattg aaaacggaaa tgctgtttct      720

tctgggtcca ttcaagagag tgtgaaagac cgagtgattg actcaagact gcagctgttt      780

atcaccaagc caggactcta cacatgcata gctaccaata agcatgggga gaagttcagt      840

actgccaagg ctgcagccac catcagcata gcagaatgga gagagtactg cttggcagta      900

aaggagctct tctgcgcaaa agaatggctg gtaatggaag agaagaccca cagaggactc      960

tacagatccg agatgcattt gctgtccgtg ccagaatgca gcaagcttcc cagcatgcat     1020

tgggacccca cggcctgtgc cagactgcca catctagcat tcccaccaat gacgtcctca     1080

aagccaagtg tggacattcc aaatctgcct tcctcctcct cttcttcctt ctctgtctca     1140

cctacatact ccatgact                                                   1158


<210>  4065
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  4065
gttctcctgc actcagggtc ctcggtaccc gccgctgctg gcagctccgt ggtgtccgag       60

tccgcggtga gctgggaggc gggcgcccgg gcggtgctgc gctgccagag cccgcgcatg      120

gtgtggaccc aggaccggct gcacgaccgc cagcgcgtgc tccactggga cctgcgcggc      180

cccgggggtg gccccgcgcg gcgcctgctg gacttgtact cggcgggcga gcagcgcgtg      240

tacgaggcgc gggaccgcgg ccgcctggag ctctcggcct cggccttcga cgacggcaac      300

ttctcgctgc tcatccgcgc ggtggaggag acggacgcgg ggctgtacac ctgcaacctg      360

caccatcact actgccacct ctacgagagc ctggccgtcc gcctggaggt caccgacggc      420

cccccggcca cccccgccta ctgggacggc gagaaggagg tgctggcggt ggcgcgcggc      480

gcacccgcgc ttctgacctg cgtgaaccgc gggcacgtgt ggaccgaccg gcacgtggag      540

gaggctcaac aggtggtgca ctgggaccgg cagccgcccg gggtcccgca cgaccgcgcg      600

gaccgcctgc tggacctcta cgcgtcgggc gagcgccgcg cctacgggcc cctttttctg      660

cgcgaccgcg tggctgtggg cgcggatgcc tttgagcgcg gtgacttctc actgcgtatc      720

gagccgctgg aggtcgccga cgagggcacc tactcctgcc acctgcacca ccattactgt      780

ggcctgcacg aacgccgcgt cttccacctg acggtcgccg aaccccacgc ggagccgccc      840

ccccggggct ctccgggcaa cggctccagc cacagcggcg ccccaggccc agaccccaca      900

ctggcgcgcg gccacaacgt catcaatgtc atcgtccccg agagccgagc ccacttcttc      960

cagcag                                                                 966


<210>  4066
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  4066
atggcgacct ccacgggtcg ctggcttctc ctccggcttg cactattcgg cttcctctgg       60

gaagcgtccg gcggcctcga ctcgggggcc tcccgcgacg acgacttgct actgccctat      120

ccacgcgcgc gcgcgcgcct cccccgggac tgcacacggg tgcgcgccgg caaccgcgag      180

cacgagagtt ggcctccgcc tcccgcgact cccggcgccg gcggtctggc cgtgcgcacc      240

ttcgtgtcgc acttcaggga ccgcgcggtg gccggccacc tgacgcgggc cgttgagccc      300

ctgcgcacct tctcggtgct ggagcccggt gggcccggcg gctgcgcggc gagacgacgc      360

gccaccgtgg aggagacggc gcgggcggcc gactgccgtg tcgcccagaa cggcggcttc      420

ttccgcatga actcgggcga gtgcctgggg aacgtggtga gcgacgagcg gcgggtgagc      480

agctccgggg ggctgcagaa cgcgcagttc gggatccgcc gcgacgggac cctggtcacc      540

gggtacctgt ctgaggagga ggtgctggac actgagaacc catttgtgca gctgctgagt      600

ggggtcgtgt ggctgattcg taatggaagc atctacatca acgagagcca agccacagag      660

tgtgacgaga cacaggagac aggttccttt agcaaatttg tgaatgtgat atcagccagg      720

acggccattg gccacgaccg gaaagggcag ctggtgctct ttcatgcaga cggccaaacg      780

gagcagcgtg gcatcaacct gtgggaaatg gcggagttcc tgctgaaaca ggacgtggtc      840

aacgccatca acctggatgg gggtggctct gccacctttg tgctcaacgg gaccttggcc      900

agttacccgt cagatcactg gcaggcg                                          927


<210>  4067
<211>  2097
<212>  DNA
<213>  Homo Sapiens

<400>  4067
ctgcaggtgg atattgttcc cagccagggg gagatcagcg ttggagagtc caaattcttc       60

ttatgccaag tggcaggaga tgccaaagat aaagacatct cctggttctc ccccaatgga      120

gaaaagctca ccccaaacca gcagcggatc tcagtggtgt ggaatgatga ttcctcctcc      180

accctcacca tctataacgc caacatcgac gacgccggca tttacaagtg tgtggttaca      240

ggcgaggatg gcagtgagtc agaggccacc gtcaacgtga agatctttca gaagctcatg      300

ttcaagaatg cgccaacccc acaggagttc cgggaggggg aagatgccgt gattgtgtgt      360

gatgtggtca gctccctccc accaaccatc atctggaaac acaaaggccg agatgtcatc      420

ctgaaaaaag atgtccgatt catagtcctg tccaacaact acctgcagat ccggggcatc      480

aagaaaacag atgagggcac ttatcgctgt gagggcagaa tcctggcacg gggggagatc      540

aacttcaagg acattcaggt cattgtgaat gtgccaccta ccatccaggc caggcagaat      600

attgtgaatg ccaccgccaa cctcggccag tccgtcaccc tggtgtgcga tgccgaaggc      660

ttcccagagc ccaccatgag ctggacaaag gatggggaac agatagagca agaggaagac      720

gatgagaagt acatcttcag cgacgatagt tcccagctga ccatcaaaaa ggtggataag      780

aacgacgagg ctgagtacat ctgcattgct gagaacaagg ctggcgagca ggatgcgacc      840

atccacctca aagtctttgc aaaacccaaa atcacatatg tagagaacca gactgccatg      900

gaattagagg agcaggtcac tcttacctgt gaagcctccg gagaccccat tccctccatc      960

acctggagga cttctacccg gaacatcagc agcgaagaaa aggcttcgtg gactcgacca     1020

gagaagcaag agactctgga tgggcacatg gtggtgcgta gccatgcccg tgtgtcgtcg     1080

ctgaccctga agagcatcca gtacactgat gccggagagt acatctgcac cgccagcaac     1140

accatcggcc aggactccca gtccatgtac cttgaagtgc aatatgcccc aaagctacag     1200

ggccctgtgg ctgtgtacac ttgggagggg aaccaggtga acatcacctg cgaggtattt     1260

gcctatccca gtgccacgat ctcatggttt cgggatggcc agctgctgcc aagctccaat     1320

tacagcaata tcaagatcta caacaccccc tctgccagct atctggaggt gaccccagac     1380

tctgagaatg attttgggaa ctacaactgt actgcagtga accgcattgg gcaggagtcc     1440

ttggaattca tccttgttca agcagacacc ccctcttcac catccatcga ccaggtggag     1500

ccatactcca gcacagccca ggtgcagttt gatgaaccag aggccacagg tggggtgccc     1560

atcctcaaat acaaagctga gtggagagca gtgggtgaag aagtatggca ttccaagtgg     1620

tatgatgcca aggaagccag catggagggc atcgtcacca tcgtgggcct gaagcccgaa     1680

acaacgtacg ccgtaaggct ggcggcgctc aatggcaaag ggctgggtga gatcagcgcg     1740

gcctccgagt tcaagacgca gccagtccaa ggggaaccca gtgcacctaa gctcgaaggg     1800

cagatgggag aggatggaaa ctctattaaa gtgaacctga tcaagcagga tgacggcggc     1860

tcccccatca gacactatct ggtcaggtac cgagcgctct cctccgagtg gaaaccagag     1920

atcaggctcc cgtctggcag tgaccacgtc atgctgaagt ccctggactg gaatgctgag     1980

tatgaggtct acgtggtggc tgagaaccag caaggaaaat ccaaggcggc tcattttgtg     2040

ttcaggacct cggcccagcc cacagccatc ccagccaacg gcagccccac ctcaggc        2097


<210>  4068
<211>  2034
<212>  DNA
<213>  Homo Sapiens

<400>  4068
cttcttcaag tgacaatttc acttagcaaa gtagagctta gtgttggaga atctaaattc       60

ttcacatgta cagcgattgg tgaacctgaa agtatagatt ggtataatcc tcaaggagag      120

aagataattt caacacagag ggtagtagtg caaaaggaag gtgttaggtc acggttaacc      180

atctacaatg caaatataga agatgcaggg atatatcgtt gtcaagcaac agatgccaaa      240

ggacaaacac aagaagctac agtagttttg gaaatttacc aaaaactcac tttcagagaa      300

gtggtatctc cacaagaatt caaacaagga gaagatgcag aagtggtttg ccgagttagc      360

agttcacctg cacctgctgt cagctggttg tatcataatg aggaagtcac cactatttcc      420

gacaatcggt tcgctatgtt agcaaacaat aacctgcaga ttctcaacat caataaaagt      480

gatgaaggta tatacagatg tgaaggaaga gtggaggcca ggggagaaat tgacttccgt      540

gatatcattg ttattgttaa tgtgccgcca gcaatctcaa tgcctcagaa atcttttaat      600

gccacagcag agagaggaga agaaatgaca ttttcctgca gggcctcagg ctctccagaa      660

cccgccatct cctggttcag gaatggcaag ctcattgaag aaaatgagaa gtacatattg      720

aaagggagca atacagaact cactgtcagg aacataatca atagtgatgg tggtccttat      780

gtctgcaggg ccacaaataa ggcaggagaa gatgaaaagc aagctttcct ccaagtcttt      840

gtacagcctc acataataca gcttaaaaat gaaactacat atgagaatgg tcaagtcaca      900

ctcgtatgtg atgcggaagg ggagcctatt ccagaaatca cttggaaaag agctgtggat      960

ggcttcacgt tcactgaagg cgataagagc ctggacggcc gtatcgaagt caaagggcag     1020

catggaagct catcactgca tattaaagat gtgaagttgt cagattcagg gagatatgac     1080

tgtgaagctg caagcagaat tggagggcat caaaagagca tgtaccttga tattgaatat     1140

gcccccaagt ttatatcaaa ccaaacaatt tattactctt gggaaggaaa tcctatcaat     1200

ataagttgtg atgtgaaatc gaatccacca gcatcaattc actggagaag agataaatta     1260

gtcttacctg ctaaaaacac gaccaattta aagacttata gtacaggaag aaagatgata     1320

ttagagattg cacctacatc tgacaatgac tttggacgct ataattgcac agccactaat     1380

catataggaa caagatttca agaatatatt cttgctttgg ctgacgtgcc atccagtccc     1440

tatggagtga agatcataga gctgtcgcag accacggcca aggtttcctt caacaaaccg     1500

gactcccatg gaggtgtacc tattcatcac tatcaggtgg atgtcaaaga agtagcgtca     1560

gaaatctgga aaattgtacg ctcccatgga gttcaaacaa tggttgtttt gaacaacctg     1620

gaaccaaata caacttatga aatcagggtt gcagctgtaa atggaaaggg acaaggagac     1680

tacagtaaaa tagaaatctt ccaaacatta ccagttcgtg aaccaagtcc tccatccata     1740

catggacagc caagcagtgg aaagagcttt aaactcagca tcaccaaaca ggacgatgga     1800

ggggccccta ttttggaata cattgtgaaa tatagaagta aagataagga agaccaatgg     1860

ctagagaaaa aagtgcaagg aaataaagac cacatcattt tggagcatct ccagtggacc     1920

atggggtatg aagttcagat tacagctgcc aatagattgg gatattctga accgacagtt     1980

tatgaattca gcatgccacc aaagcccaac attattaaag acacgctgtt taat           2034


<210>  4069
<211>  3897
<212>  DNA
<213>  Homo Sapiens

<400>  4069
gaacagggca cacaggatat caccgatgcc agcgaaaggg ggctccacat gcagaagctg       60

gggtctgggt cagtgcaggc tgcgctggcg gagctggtgg ccctgccctg tctctttacc      120

ctgcagccac ggccaagcgc agcccgagat gcccctcgga taaagtggac caaggtgcgg      180

actgcgtcgg gccagcgaca ggacttgccc atcctggtgg ccaaggacaa tgtcgtgagg      240

gtggccaaaa gctggcaggg acgagtgtca ctgccttcct acccccggcg ccgagccaac      300

gccacgctac ttctggggcc actgagggcc agtgactctg ggctgtaccg ctgccaggtg      360

gtgaggggca tcgaggatga gcaggacctg gtgcccttgg aggtgacagg tgttgtgttc      420

cactaccgat cagcccggga ccgctatgca ctgaccttcg ctgaggccca ggaggcctgc      480

cgtctcagct cagccatcat tgcagcccct cggcatctac aggctgcctt tgaggatggc      540

tttgacaact gtgatgctgg ctggctctct gaccgcactg ttcggtatcc tatcacccag      600

tcccgtcctg gttgctatgg cgaccgtagc agccttccag gggttcggag ctatgggagg      660

cgcaacccac aggaactcta cgatgtgtat tgctttgccc gggagctggg gggcgaggtc      720

ttctacgtgg gcccggcccg ccgcctgaca ctggccggcg cgcgtgcaca gtgccgccgc      780

cagggtgccg cgctggcctc ggtgggacag ctgcacctgg cctggcatga gggcctggac      840

cagtgcgacc cgggctggct ggccgacggc agcgtgcgct acccgatcca gacgccgcgc      900

cggcgctgcg ggggcccagc cccgggcgtg cgcaccgtct accgcttcgc taaccggacc      960

ggcttcccct cacccgccga gcgcttcgac gcctactgct tccgagctca tcaccccacg     1020

tcacaacatg gagacctaga gaccccatcc tctggggatg agggggagat tctgtcagca     1080

gaggggcccc cagttagaga actggagccc accctggagg aggaagaggt ggtcacccct     1140

gacttccagg agcctctggt gtccagtggg gaagaagaaa ccctgatttt ggaggagaag     1200

caggagtctc aacagaccct cagccctacc cctggggacc ccatgctggc ctcatggccc     1260

actggggaag tgtggctaag cacggtggcc cccagcccta gcgacatggg ggcaggcact     1320

gcagcaagtt cacacacgga ggtggcccca actgacccta tgcctaggag aagggggcgc     1380

ttcaaagggt tgaatgggcg ctacttccag cagcaggaac cggagccggg gctgcaaggg     1440

gggatggagg ccagcgccca gccccccacc tcagaggctg cagtgaacca aatggagcct     1500

ccgttggcca tggcagtcac agagatgttg ggcagtggcc agagccggag cccctgggct     1560

gatctgacca atgaggtgga tatgcctgga gctggttctg ctggtggcaa gagctcccca     1620

gagccctggc tgtggccccc taccatggtc ccacccagca tctcaggcca cagcagggcc     1680

cctgtcctgg agctagagaa agccgagggc cccagtgcca ggccagccac cccagacctg     1740

ttttggtccc ccttggaggc cactgtctca gctcccagcc ctgccccctg ggaggcattc     1800

cctgtggcca cctccccaga tctccctatg atggccatgc tgcgtggtcc caaagagtgg     1860

atgctaccac accccacccc catctccacc gaggccaata gagttgaggc acatggtgag     1920

gccaccgcca cggctccacc ctcccctgct gcagagacca aggtgtattc cctgcctctc     1980

tctttgaccc caacaggaca gggtggagag gccatgccca caacacctga gtcccccagg     2040

gcagacttca gagaaactgg ggagaccagc cctgctcagg tcaacaaagc tgagcactcc     2100

agctccagcc catggccttc tgtaaacagg aatgtggctg taggttttgt ccccactgag     2160

actgccactg agccaacggg cctcaggggt atcccggggt ctgagtctgg ggtcttcgac     2220

acagcagaaa gccccacttc tggcttgcag gccactgtag atgaggtgca ggacccctgg     2280

ccctcagtgt acagcaaagg gctggatgca agttccccat ctgcccccct ggggagccct     2340

ggagtcttct tggtacccaa agtcacccca aatttggagc cttgggttgc tacagatgaa     2400

ggacccactg tgaatcccat ggattccaca gtcacgccgg cccccagtga tgctagtgga     2460

atttgggaac ctggatccca ggtgtttgaa gaagccgaaa gcaccacctt gagccctcag     2520

gtggccctgg atacaagcat tgtgacgccc ctcacgaccc tggagcaggg ggacaaggtt     2580

ggagttccag ccatgtctac actgggctcc tcaagctccc aaccccaccc agagccagag     2640

gatcaggtgg agacccaggg aacatcagga gcttcagtgc ctccgcatca gagcagtccc     2700

ctagggaaac cggctgttcc tcctgggaca ccgactgcag ccagtgtggg cgagtctgcc     2760

tcagtttcct caggggagcc tacggtaccg tgggacccct ccagcaccct gctgcctgtc     2820

accctgggca tagaggactt cgaactggag gtcctggcag ggagcccggg tgtagagagc     2880

ttctgggagg aggtggcaag tggagaggag ccagccctgc cagggacccc tatgaatgca     2940

ggtgcggagg aggtgcactc agatccctgt gagaacaacc cttgtcttca tggagggaca     3000

tgtaatgcca atggcaccat gtatggctgt agctgtgatc agggcttcgc cggggagaac     3060

tgtgagattg acattgatga ctgcctctgc agcccctgtg agaatggagg cacctgtatt     3120

gatgaggtca atggctttgt ctgcctttgc ctccccagct atgggggcag cttttgtgag     3180

aaagacaccg agggctgtga ccgcggctgg cataagttcc agggccactg ttaccgctat     3240

tttgcccacc ggagggcatg ggaagatgcc gagaaggact gccgccgccg ctccggccac     3300

ctgaccagcg tccactcacc ggaggaacac agcttcatta atagctttgg gcatgaaaac     3360

acgtggatcg gcctgaacga caggatcgtg gagagagatt tccagtggac ggacaacacc     3420

gggctgcaat ttgagaactg gcgagagaac cagccggaca atttcttcgc gggtggcgag     3480

gactgtgtgg tgatggtggc gcatgaaagc gggcgctgga acgatgtccc ctgcaactac     3540

aacctaccct atgtctgcaa gaagggcaca gtgctctgtg gtccccctcc ggcagtggag     3600

aatgcctcac tcatcggtgc ccgcaaggcc aagtacaatg tccatgccac tgtaaggtac     3660

cagtgcaatg aaggatttgc ccagcaccat gtggccacca ttcgatgccg gagcaatggc     3720

aagtgggaca ggccccaaat tgtctgcacc aaacccagac gttcacatcg gatgcggcga     3780

caccaccacc accaccaaca ccaccaccag catcaccacc acaaatcccg caaggagcgc     3840

agaaaacaca agaaacaccc aacggaggac tgggagaagg acgaagggaa tttctgc        3897


<210>  4070
<211>  708
<212>  DNA
<213>  Homo Sapiens

<400>  4070
cagcagcaga ctctcccaaa accgttcatc tgggccgagc cccatttcat ggttccaaag       60

gaaaagcaag tgaccatctg ttgccaggga aattatgggg ctgttgaata ccagctgcac      120

tttgaaggaa gcctttttgc cgtggacaga ccaaaacccc ctgagcggat taacaaagtc      180

aaattctaca tcccggacat gaactcccgc atggcagggc aatacagctg catctatcgg      240

gttggggagc tctggtcaga gcccagcaac ttgctggatc tggtggtaac agaaatgtat      300

gacacaccca ccctctcggt tcatcctgga cccgaagtga tctcgggaga gaaggtgacc      360

ttctactgcc gtctagacac tgcaacaagc atgttcttac tgctcaagga gggaagatcc      420

agccacgtac agcgcggata cgggaaggtc caggcggagt tccccctggg ccctgtgacc      480

acagcccacc gagggacata ccgatgtttt ggctcctata acaaccatgc ctggtctttc      540

cccagtgagc cagtgaagct cctggtcaca ggcgacattg agaacaccag ccttgcacct      600

gaagacccca cctttcctga cacttggggc acctaccttt taaccacaga gacgggactc      660

cagaaagacc atgccctctg ggatcacact gcccagaatc tccttcgg                   708


<210>  4071
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  4071
caaagtaaag cccaggtttt acagagtgtg gcaggacaaa ccctaactgt aagatgccag       60

tatcctccaa cggggtctct atatgaaaag aagggctggt gtaaggaggc gtccgcctta      120

gtctgcatac gtctggtaac ttcaagtaaa ccaagaacga tggcatggac ctcacgtttc      180

accatttggg acgatcccga tgctggtttc tttactgtaa ccatgacaga cctaagagaa      240

gaagattccg ggcactattg gtgtcgtatc tataggccga gcgacaattc agtatccaaa      300

tctgtgagat tctatttggt ggttagcccg gcttctgcat caacccagac cagttggacc      360

cccagagatt tagtaagttc tcagacgcaa actcaaagct gcgtcccacc gacagccggc      420

gccaggcagg cgcccgaatc accctctact atacccgtac cgtcccaacc ccaaaattcc      480

actttgagac ctgggccagc tgccccaata gcg                                   513


<210>  4072
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4072
ctctgggtgt cccagccccc tgagattcgt accctggaag gatcctctgc cttcctgccc       60

tgctccttca atgccagcca agggagactg gccattggct ccgtcacgtg gttccgagat      120

gaggtggttc cagggaagga ggtgaggaat ggaaccccag agttcagggg ccgcctggcc      180

ccacttgctt cttcccgttt cctccatgac caccaggctg agctgcacat ccgggacgtg      240

cgaggccatg acgccagcat ctacgtgtgc agagtggagg tgctgggcct tggtgtcggg      300

acagggaatg ggactcggct ggtggtggag aaagaacatc ctcagctagg g               351


<210>  4073
<211>  1647
<212>  DNA
<213>  Homo Sapiens

<400>  4073
cagaagttac ccacccggga tgaggaactt tttcagatgc agatccggga caaggcattt       60

tttcatgatt cgtcagtaat tccagatgga gctgaaatta gcagttatct ctttagagat      120

acacctaaaa ggtatttctt tgtggttgaa gaagacaata ctccattatc agtcacagtg      180

acgccctgtg atgcgccttt ggagtggaag ctgagcctcc aggagctgcc agaggacagg      240

agcggggaag gctcaggtga tctggaacct cttgagcagc agaagcagca gatcattaat      300

gaggaaggca ctgagttatt ctcctacaaa ggcaatgatg ttgagtattt tatatcgtct      360

agttccccat ccggtttata tcagttggat cttctttcaa cagagaaaga cacacatttc      420

aaagtatatg ccaccacaac tccagaatct gatcagccat accctgagtt accctatgac      480

ccaagagtag atgtgacctc actggggcgc accacggtca ctttggcctg gaaaccaagc      540

cccactgcct ctttgctgaa acaacccatt cagtactgtg tggtcatcaa caaagagcac      600

aatttcaaaa gtctctgtgc agtggaagca aaactgagtg cagatgatgc ttttatgatg      660

gcaccgaaac ctggtctgga cttcagcccc tttgactttg cccactttgg atttccttct      720

gataattcag gtaaagaacg cagtttccag gcaaagcctt ctccaaaact ggggcgtcat      780

gtctactcca ggcccaaggt tgatattcag aaaatctgca taggaaacaa gaacatcttc      840

accgtctctg atctgaaacc cgacacgcag tactactttg acgtatttgt ggtcaacatc      900

aacagcaaca tgagcaccgc ttatgtaggt acctttgcca ggaccaagga agaagccaaa      960

cagaagacag tcgagctcaa agatgggaag ataacagatg tatttgttaa aaggaaggga     1020

gcaaagtttc tacggtttgc tccagtctct tctcaccaaa aagtcacctt ctttattcac     1080

tcttgtctgg atgctgtcca aatccaagtg agaagagatg ggaaacttct tctgtctcag     1140

aatgtggaag gcattcagca gtttcagctt agaggaaaac ctaaagctaa atacctcgtt     1200

cgactgaaag gaaacaagaa aggagcatct atgttgaaaa ttctagctac cacaaggcct     1260

actaagcagt catttccctc tcttcctgaa gacacaagaa tcaaagcctt tgacaagctc     1320

cgtacctgtt cctcggccac cgtggcttgg ctaggcactc aggaaaggaa caagttttgc     1380

atctacaaaa aagaagtgga tgataactac aatgaagacc agaagaaaag agagcaaaac     1440

caatgtctag gaccagatat aaggaagaag tcagaaaagg tcctctgtaa atatttccac     1500

agtcaaaacc tgcagaaagc agtgaccaca gaaacaatta aaggtcttca gcctggcaaa     1560

tcttacctgc tggatgttta tgtcatagga catggggggc actctgtaaa gtatcagagt     1620

aaggttgtga aaactagaaa gttctgt                                         1647


<210>  4074
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  4074
atgcaggtgc atctaactgt gcaagttcct cctaagatat atgacatctc aaatgatatg       60

accgtcaatg aaggaaccaa cgtcactctt acttgtttgg ccactgggaa accagagcct      120

tccatttctt ggcgacacat ctccccatca gcaaaaccat ttgaaaatgg acaatatttg      180

gacatttatg gaattacaag ggaccaggct ggggaatatg aatgcagtgc ggaaaatgat      240

gtgtcattcc cagatgtgag gaaagtaaaa gttgttgtca actttgctcc tactattcag      300

gaaattaaat ctggcaccgt gacccccgga cgcagtggcc tgataagatg tgaaggtgca      360

ggtgtgccgc ctccagcctt tgaatggtac aaaggagaga agaagctctt caatggccaa      420

caaggaatta ttattcaaaa ttttagcaca agatccattc tcactgttac caacgtgaca      480

caggagcact tcggcaatta tacttgtgtg gctgccaaca agctaggcac aaccaatgcg      540

agcctgcctc ttaaccctcc aagtacagcc cagtatggaa ttaccggg                   588


<210>  4075
<211>  2367
<212>  DNA
<213>  Homo Sapiens

<400>  4075
tttgggatgg accctgacct tcagatggat atcgtcaccg agcttgacct tgtgaacacc       60

acccttggag ttgctcaggt gtctggaatg cacaatgcca gcaaagcatt tttatttcaa      120

gacatagaaa gagagatcca tgcagctcct catgtgagtg agaaattaat tcagctgttc      180

cagaacaaga gtgaattcac cattttggcc actgtacagc agaagccatc cacttcagga      240

gtgatactgt ccattcgaga actggagcac agctattttg aactggagag cagtggcctg      300

agggatgaga ttcggtatca ctacatacac aatgggaagc caaggacaga ggcacttcct      360

taccgcatgg cagatggaca atggcacaag gttgcactgt cagttagcgc ctctcatctc      420

ctgctccatg tcgactgtaa caggatttat gagcgtgtga tagaccctcc agataccaac      480

cttcccccag gaatcaattt atggcttggc cagcgcaacc aaaagcatgg cttattcaaa      540

gggatcatcc aagatgggaa gatcatcttt atgccgaatg gatatataac acagtgtcca      600

aatctaaatc acacttgccc aacctgcagt gatttcttaa gcctggtgca aggaataatg      660

gatttacaag agcttttggc caagatgact gcaaaactaa attatgcaga gacaagactt      720

agtcaattgg aaaactgtca ttgtgagaag acttgtcaag tgagtggact gctctatcga      780

gatcaagact cttgggtaga tggtgaccat tgcaggaact gcacttgcaa aagtggtgcc      840

gtggaatgcc gaaggatgtc ctgtccccct ctcaattgct ccccagactc cctcccagtg      900

cacattgctg gccagtgctg taaggtctgc cgaccaaaat gtatctatgg aggaaaagtt      960

cttgcagaag gccagcggat tttaaccaag agctgtcggg aatgccgagg tggagtttta     1020

gtaaaaatta cagaaatgtg tcctcctttg aactgctcag aaaaggatca cattcttcct     1080

gagaatcagt gctgccgtgt ctgtagaggt cataactttt gtgcagaagg acctaaatgt     1140

ggtgaaaact cagagtgcaa aaactggaat acaaaagcta cttgtgagtg caagagtggt     1200

tacatctctg tccagggaga ctctgcctac tgtgaagata ttgatgagtg tgcagctaag     1260

atgcattact gtcatgccaa tactgtgtgt gtcaaccttc ctgggttata tcgctgtgac     1320

tgtgtcccag gatacattcg tgtggatgac ttctcttgta cagaacacga tgaatgtggc     1380

agcggccagc acaactgtga tgagaatgcc atctgcacca acactgtcca gggacacagc     1440

tgcacctgca aaccgggcta cgtggggaac gggaccatct gcagagcttt ctgtgaagag     1500

ggctgcagat acggtggaac gtgtgtggct cccaacaaat gtgtctgtcc atctggattc     1560

acaggaagcc actgcgagaa agatattgat gaatgttcag agggaatcat tgagtgccac     1620

aaccattccc gctgcgttaa cctgccaggg tggtaccact gtgagtgcag aagcggtttc     1680

catgacgatg ggacctattc actgtccggg gagtcctgta ttgacattga tgaatgtgcc     1740

ttaagaactc acacctgttg gaacgattct gcctgcatca acctggcagg gggttttgac     1800

tgtctctgcc cctctgggcc ctcctgctct ggtgactgtc ctcatgaagg ggggctgaag     1860

cacaatggcc aggtgtggac cttgaaagaa gacaggtgtt ctgtctgctc ctgcaaggat     1920

ggcaagatat tctgccgacg gacagcttgt gattgccaga atccaagtgc tgacctattc     1980

tgttgcccag aatgtgacac cagagtcaca agtcaatgtt tagaccaaaa tggtcacaag     2040

ctgtatcgaa gtggagacaa ttggacccat agctgtcagc agtgtcggtg tctggaagga     2100

gaggtagatt gctggccact cacttgcccc aacttgagct gtgagtatac agctatctta     2160

gaaggggaat gttgtccccg ctgtgtcagt gacccctgcc tagctgataa catcacctat     2220

gacatcagaa aaacttgcct ggacagctat ggtgtttcac ggcttagtgg ctcagtgtgg     2280

acgatggctg gatctccctg cacaacctgt aaatgcaaga atggaagagt ctgttgttct     2340

gtggattttg agtgtcttca aaataat                                         2367


<210>  4076
<211>  2385
<212>  DNA
<213>  Homo Sapiens

<400>  4076
cttggtgtgg acccttccct acagattgac gtcttaacag agttagaact tggggagtcc       60

acgaccggag tgcgtcaggt cccggggctg cataatggga cgaaagcctt tctctttcaa      120

gatactccca gaagcataaa agcatccact gctacagctg aacagttttt tcagaagctg      180

agaaataaac atgaatttac tattttggtg accctaaaac agacccactt aaattcagga      240

gttattctct caattcacca cttggatcac aggtacctgg aactggaaag tagtggccat      300

cggaatgaag tcagactgca ttaccgctca ggcagtcacc gccctcacac agaagtgttt      360

ccttacattt tggctgatga caagtggcac aagctctcct tagccatcag tgcttcccat      420

ttgattttac acattgactg caataaaatt tatgaaaggg tagtagaaaa gccctccaca      480

gacttgcctc taggcacaac attttggcta ggacagagaa ataatgcgca tggatatttt      540

aagggtataa tgcaagatgt ccaattactt gtcatgcccc agggatttat tgctcagtgc      600

ccagatctta atcgcacctg tccaacttgc aatgacttcc atggacttgt gcagaaaatc      660

atggagctac aggatatttt agccaaaaca tcagccaagc tgtctcgagc tgaacagcga      720

atgaatagat tggatcagtg ctattgtgaa aggacttgca ccatgaaggg aaccacctac      780

cgagaatttg agtcctggat agacggctgt aagaactgca catgcctgaa tggaaccatc      840

cagtgtgaaa ctctaatctg cccaaatcct gactgcccac ttaagtcggc tcttgcgtat      900

gtggatggca aatgctgtaa ggaatgcaaa tcgatatgcc aatttcaagg acgaacctac      960

tttgaaggag aaagaaatac agtctattcc tcttctggag tatgtgttct ctatgagtgc     1020

aaggaccaga ccatgaaact tgttgagagt tcaggctgtc cagctttgga ttgtccagag     1080

tctcatcaga taaccttgtc tcacagctgt tgcaaagttt gtaaaggtta tgacttttgt     1140

tctgaaaggc ataactgcat ggagaattcc atctgcagaa atctgaatga cagggctgtt     1200

tgtagctgtc gagatggttt tagggctctt cgagaggata atgcctactg tgaagacatc     1260

gatgagtgtg ctgaagggcg ccattactgt cgtgaaaata caatgtgtgt caacaccccg     1320

ggttctttta tgtgcatctg caaaactgga tacatcagaa ttgatgatta ttcatgtaca     1380

gaacatgatg agtgtatcac aaatcagcac aactgtgatg aaaatgcttt atgcttcaac     1440

actgttggag gacacaactg tgtttgcaag ccgggctata cagggaatgg aacgacatgc     1500

aaagcatttt gcaaagatgg ctgtaggaat ggaggagcct gtattgccgc taatgtgtgt     1560

gcctgcccac aaggcttcac tggacccagc tgtgaaacgg acattgatga atgctctgat     1620

ggttttgttc aatgtgacag tcgtgctaat tgcattaacc tgcctggatg gtaccactgt     1680

gagtgcagag atggctacca tgacaatggg atgttttcac caagtggaga atcgtgtgaa     1740

gatattgatg agtgtgggac cgggaggcac agctgtgcca atgataccat ttgcttcaat     1800

ttggatggcg gatatgattg tcgatgtcct catggaaaga attgcacagg ggactgcatc     1860

catgatggaa aagttaagca caatggtcag atttgggtgt tggaaaatga caggtgctct     1920

gtgtgctcat gtcagaatgg attcgttatg tgtcgacgga tggtctgtga ctgtgagaat     1980

cccacagttg atcttttttg ctgccctgaa tgtgacccaa ggcttagtag tcagtgcctc     2040

catcaaaatg gggaaacttt gtataacagt ggtgacacct gggtccagaa ttgtcaacag     2100

tgccgctgct tgcaagggga agttgattgt tggcccctgc cttgcccaga tgtggagtgt     2160

gaattcagca ttctcccaga gaatgagtgc tgcccgcgct gtgtcacaga cccttgccag     2220

gctgacacca tccgcaatga catcaccaag acttgcctgg acgaaatgaa tgtggttcgc     2280

ttcaccgggt cctcttggat caaacatggc actgagtgta ctctctgcca gtgcaagaat     2340

ggccacatct gttgctcagt ggatccacag tgccttcagg aactg                     2385


<210>  4077
<211>  3216
<212>  DNA
<213>  Homo Sapiens

<400>  4077
gccaggagcg gctccgcgcc gcagtcccca ggagccagca ttcgaacgtt cactccattt       60

tattttctgg tggagccggt ggatacactc tcagttagag gctcttctgt tatattaaac      120

tgttcagcat attctgagcc ttctccaaaa attgaatgga aaaaagatgg aactttttta      180

aacttagtat cagatgatcg acgccagctt ctcccggatg gatctttatt tatcagcaat      240

gtggtgcatt ccaaacacaa taaacctgat gaaggttatt atcagtgtgt ggccactgtt      300

gagagtcttg gaactattat cagtagaaca gcgaagctca tagtagcagg tcttccaaga      360

tttaccagcc aaccagaacc ttcctcagtt tatgctggga acaatgcaat tctgaattgt      420

gaagttaatg cagatttggt cccatttgtg aggtgggaac agaacagaca accccttctt      480

ctggatgata gagttatcaa acttccaagt ggaatgctgg ttatcagcaa tgcaactgaa      540

ggagatggcg ggctttatcg ctgcgtagtg gaaagtggtg ggccaccaaa gtatagtgat      600

gaagttgaat tgaaggttct tccagatcct gaggtgatat cagacttggt atttttgaaa      660

cagccttctc ccttagtcag agtcattggt caggatgtag tgttgccatg tgttgcttca      720

ggacttccta ctccaaccat taaatggatg aaaaatgagg aggcacttga cacagaaagc      780

tctgaaagat tggtattgct ggcaggtggt agcctggaga tcagtgatgt tactgaggat      840

gatgctggga cttatttttg tatagctgat aatggaaatg agacaattga agctcaagca      900

gagcttacag tgcaagctca acctgaattc ctgaagcagc ctactaatat atatgctcac      960

gaatctatgg atattgtatt tgaatgtgaa gtgactggaa aaccaactcc aactgtgaag     1020

tgggtcaaaa atggggatat ggttatccca agtgattatt ttaagattgt aaaggaacat     1080

aatcttcaag ttttgggtct ggtgaaatca gatgaagggt tctatcagtg cattgctgaa     1140

aatgatgttg gaaatgcaca agctggagcc caactgataa tccttgaaca tgcaccagcc     1200

acaacgggac cactgccttc agctcctcgg gatgtcgtgg cctccctggt ctctacccgc     1260

ttcatcaaat tgacgtggcg gacacctgca tcagatcctc acggagacaa ccttacctac     1320

tctgtgttct acaccaagga agggattgct agggaacgtg ttgagaatac cagtcaccca     1380

ggagagatgc aagtaaccat tcaaaaccta atgccagcga ccgtgtacat ctttagagtt     1440

atggctcaaa ataagcatgg ctcaggagag agttcagctc cactgcgagt agaaacacaa     1500

cctgaggttc agctccctgg cccagcacct aaccttcgtg catatgcagc ttcgcctacc     1560

tccatcactg ttacgtggga aacaccagtg tctggcaatg gggaaattca gaattataaa     1620

ttgtactaca tggaaaaggg gactgataaa gaacaggatg ttgatgtttc aagtcactct     1680

tacaccatta atgggttgaa aaaatataca gagtatagtt tccgagtggt ggcctacaat     1740

aaacatggtc ctggagtttc cacaccagat gttgctgttc gaacattgtc agatgttccc     1800

agtgctgctc ctcagaatct gtccttggaa gtgagaaatt caaagagtat tatgattcac     1860

tggcagccac ctgctccagc cacacaaaat gggcagatta ctggctacaa gattcgctac     1920

cgaaaggcct cccgaaagag tgatgtcact gagaccttgg taagcgggac acagctgtct     1980

cagctgattg aaggtcttga tcgggggact gagtataatt tccgagtggc tgctctaaca     2040

atcaatggta caggcccggc aactgactgg ctgtctgctg aaacttttga aagtgaccta     2100

gatgaaactc gtgttcctga agtgcctagc tctcttcacg tacgcccgct cgttactagc     2160

atcgtagtga gctggactcc tccagagaat cagaacattg tggtcagagg ttacgccatt     2220

ggttatggca ttggcagccc tcatgcccag accatcaaag tggactataa acagcgctat     2280

tacaccattg aaaatctgga tcccagctct cactatgtga ttaccctgaa agcatttaat     2340

aacgtgggtg aaggcatccc cctgtatgag agtgctgtga ccaggcctca cacagacact     2400

tctgaagttg atttatttgt tattaatgct ccatacactc cagtgccaga tcccactccc     2460

atgatgccac cagtgggagt tcaggcttcc attctgagtc atgacaccat caggattacg     2520

tgggcagaca actcgctgcc caagcaccag aagattacag actcccgata ctacaccgtc     2580

cgatggaaaa ccaacatccc agcaaacacc aagtacaaga atgcaaatgc aaccactttg     2640

agttatttgg tgactggttt aaagccgaat acactctatg aattctctgt gatggtgacc     2700

aaaggtcgaa gatcaagtac atggagtatg acagcccatg ggaccacctt tgaattagtt     2760

ccgacttctc cacccaagga tgtgactgtt gtgagtaaag aggggaaacc taagaccata     2820

attgtgaatt ggcagcctcc ctccgaagcc aatggcaaaa ttacaggtta catcatatat     2880

tacagtacag atgtgaatgc agagatacat gactgggtta ttgagcctgt tgtgggaaac     2940

agactgactc accagataca agagttaact cttgacacac catactactt caaaatccag     3000

gcacggaact caaagggcat gggacccatg tctgaagctg tccaattcag aacacctaaa     3060

gcggactcct ctgataaaat gcctaatgat caagcctcag ggtctggagg gaaaggaagc     3120

cggctgccag acctaggatc cgactacaaa cctccaatga gcggcagtaa cagccctcat     3180

gggagcccca cctctcctct ggacagtaat atgctg                               3216


<210>  4078
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4078
cagtcagtga cccacaccgg cctgcccatc atggcctccc tggccaacac agctatctcc       60

ttcagctgca ggatcaccta tccatacact ccccaattca aggttttcac agtcagctac      120

tttcatgaag atctccaggg acagaggagc cctaagaagc caacaaactg ccaccctgga      180

ctgggcacag agaaccagag ccacaccctg gactgccagg tcacccttgt gctgccggga      240

gcatcggcca ctggcaccta ctactgctct gtccactggc cacactccac ggtgagaggc      300

agcggcacct tcatcctggt cagagacgca gggtaccgag agcccccgca gagtccacag      360

aag                                                                    363


<210>  4079
<211>  3258
<212>  DNA
<213>  Homo Sapiens

<400>  4079
atcgaaattc ctatggatcc aagcattcag aatgagctga cgcagccgcc aaccatcacc       60

aagcagtcag cgaaggatca catcgtggac ccccgtgata acatcctgat tgagtgtgaa      120

gcaaaaggga accctgcccc cagcttccac tggacacgaa acagcagatt cttcaacatc      180

gccaaggacc cccgggtgtc catgaggagg aggtctggga ccctggtgat tgacttccgc      240

agtggcgggc ggccggagga atatgagggg gaatatcagt gcttcgcccg caacaaattt      300

ggcacggccc tgtccaatag gatccgcctg caggtgtcta aatctcctct gtggcccaag      360

gaaaacctag accctgtcgt ggtccaagag ggcgctcctt tgacgctcca gtgcaacccc      420

ccgcctggac ttccatcccc ggtcatcttc tggatgagca gctccatgga gcccatcacc      480

caagacaaac gtgtctctca gggccataac ggagacctat acttctccaa cgtgatgctg      540

caggacatgc agaccgacta cagttgtaac gcccgcttcc acttcaccca caccatccag      600

cagaagaacc ctttcaccct caaggtcctc accacccgag gagttgcaga aagaacacca      660

agcttcatgt atccccaggg caccgcgagc agccagatgg tgcttcgtgg catggacctc      720

ctgctggaat gcatcgcctc cggggtccca acaccagaca tcgcatggta caagaaaggt      780

ggggacctcc catctgataa ggccaagttt gagaacttta ataaggccct gcgtatcaca      840

aatgtctctg aggaagactc cggggagtat ttctgcctgg cctccaacaa gatgggcagc      900

atccggcaca cgatctcggt gagagtaaag gctgctccct actggctgga cgaacccaag      960

aaccttattc tggctcctgg cgaggatggg agactggtgt gtcgagccaa tggaaacccc     1020

aaacccactg tccagtggat ggtgaatggg gaacctttgc aatcggcacc acctaaccca     1080

aaccgtgagg tggccggaga caccatcatc ttccgggaca cccagatcag cagcagggct     1140

gtgtaccagt gcaacacctc caacgagcat ggctacctgc tggccaacgc ctttgtcagt     1200

gtgctggatg tgccgcctcg gatgctgtcg ccccggaacc agctcattcg agtgattctt     1260

tacaaccgga cgcggctgga ctgccctttc tttgggtctc ccatccccac actgcgatgg     1320

tttaagaatg ggcaaggaag caacctggat ggtggcaact accatgttta tgagaacggc     1380

agtctggaaa ttaagatgat ccgcaaagag gaccagggca tctacacctg tgtcgccacc     1440

aacatcctgg gcaaagctga aaaccaagtc cgcctggagg tcaaagaccc caccaggatc     1500

taccggatgc ccgaggacca ggtggccaga aggggcacca cggtgcagct ggagtgtcgg     1560

gtgaagcacg acccctccct gaaactcacc gtctcctggc tgaaggatga cgagccgctc     1620

tatattggaa acaggatgaa gaaggaagac gactccctga ccatctttgg ggtggcagag     1680

cgggaccagg gcagttacac gtgtgtcgcc agcaccgagc tagaccaaga cctggccaag     1740

gcctacctca ccgtgctagc tgatcaggcc actccaacta accgtttggc tgccctgccc     1800

aaaggacggc cagaccggcc ccgggacctg gagctgaccg acctggccga gaggagcgtg     1860

cggctgacct ggatccccgg ggatgctaac aacagcccca tcacagacta cgtcgtccag     1920

tttgaagaag accagttcca acctggggtc tggcatgacc attccaagta ccccggcagc     1980

gttaactcag ccgtcctccg gctgtccccg tatgtcaact accagttccg tgtcattgcc     2040

atcaacgagg ttgggagcag ccaccccagc ctcccatccg agcgctaccg aaccagtgga     2100

gcaccccccg agtccaatcc tggtgacgtg aagggagagg ggaccagaaa gaacaacatg     2160

gagatcacgt ggacgcccat gaatgccacc tcggcctttg gccccaacct gcgctacatt     2220

gtcaagtgga ggcggagaga gactcgagag gcctggaaca acgtcacagt gtggggctct     2280

cgctacgtgg tggggcagac cccagtctac gtgccctatg agatccgagt ccaggctgaa     2340

aatgacttcg ggaagggccc tgagccagag tccgtcatcg gttactccgg agaagattta     2400

cccagtgccc ctaggcgttt ccgagtccgg cagcccaacc tggagacaat caacctggaa     2460

tgggatcatc ctgagcatcc aaatgggatc atgattggat acactctcaa atatgtggcc     2520

tttaacggga ccaaagtagg aaagcagata gtggaaaact tctctcccaa tcagaccaag     2580

ttcacggtgc aaagaacgga ccccgtgtca cgctaccgct ttaccctcag cgccaggacg     2640

caggtgggct ctggggaagc cgtcacagag gagtcaccag cacccccgaa tgaagctact     2700

ccaaccgcag ctcctcccac attgcccccg actaccgtgg gtgcgacggg cgctgtgagc     2760

agtaccgatg ctactgccat tgctgccacc accgaagcca caacagtccc catcatccca     2820

actgtcgcac ctaccaccat cgccaccacc accaccgtcg ccacaactac tacaaccact     2880

gctgccgcca ccaccaccac ggagagtcct cccaccacca cctccgggac taagatacac     2940

gaatccgccc ctgatgagca gtccatatgg aacgtcacgg tgctccccaa cagtaaatgg     3000

gccaacatca cctggaagca caatttcggg cccggaactg actttgtggt tgagtacatc     3060

gacagcaacc atacgaaaaa aactgtccca gttaaggccc aggctcagcc tatacagctg     3120

acagacctct atcccgggat gacatacacg ttgcgggttt attcccggga caacgagggc     3180

atcagcagta ccgtcatcac ctttatgacc agtacagctt acaccaacaa ccaagcagac     3240

atcgccaccc agggctgg                                                   3258


<210>  4080
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  4080
tcatcatccc atcccatctt ccacaggggc gaattctcgg tgtgtgacag tgtcagcgtg       60

tgggttgggg ataagaccac cgccacagac atcaagggca aggaggtgat ggtgttggga      120

gaggtgaaca ttaacaacag tgtattcaaa cagtactttt ttgagaccaa gtgccgggac      180

ccaaatcccg ttgacagcgg gtgccggggc attgactcaa agcactggaa ctcatattgt      240

accacgactc acacctttgt caaggcgctg accatggatg gcaagcaggc tgcctggcgg      300

tttatccgga tagatacggc ctgtgtgtgt gtgctcagca ggaaggctgt gagaagagcc      360


<210>  4081
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  4081
aaggaggcat gtcccacggg attatacacc cactcaggcg aatgctgcaa ggcatgcaat       60

ctaggcgaag gcgtggcgca accctgcggt gccaatcaaa cggtttgtga accgtgtctg      120

gattcagtca ccttctctga tgttgttagc gccacagagc cgtgcaagcc ctgcactgag      180

tgcgtgggcc tacaaagtat gtccgcgcct tgcgtagagg ccgatgatgc tgtctgccgt      240

tgcgcttatg gctattatca agatgaaaca acgggccgtt gcgaagcatg ccgtgtctgt      300

gaagcaggta gtggactggt atttagttgc caggataagc aaaatacggt ctgcgaagaa      360

tgtccggacg gcacctacag cgatgaggcc aatcatgttg acccctgtct gccgtgtacc      420

gtctgtgagg ataccgagag gcaacttagg gaatgcacga ggtgggctga cgcagaatgt      480

gaggagatac cgggcaggtg gatcaccagg agcacccccc ctgagggttc agattctacg      540

gcaccctcca ctcaggagcc tgaggctccc cctgagcagg atcttatcgc cagtaccgtt      600

gccggcgtag ttacaaccgt catggggtcc agccaaccag tcgttacacg tggaacaacg      660

gataac                                                                 666


<210>  4082
<211>  2187
<212>  DNA
<213>  Homo Sapiens

<400>  4082
tcccgccaga cgtgtgctaa caacagacac cagtgctcgg tgcacgcaga gtgcagggac       60

tacgccacgg gcttctgctg cagctgtgtc gctggctata cgggcaatgg caggcaatgt      120

gttgcagaag gttcccccca gcgagtcaat ggcaaggtga aaggaaggat ctttgtgggg      180

agcagccagg tccccattgt ctttgagaac actgacctcc actcttacgt agtaatgaac      240

cacgggcgct cctacacagc catcagcacc attcccgaga ccgttggata ttctctgctt      300

ccactggccc cagttggagg catcattgga tggatgtttg cagtggagca ggacggattc      360

aagaatgggt tcagcatcac cgggggtgag ttcactcgcc aggctgaggt gaccttcgtg      420

gggcacccgg gcaatctggt cattaagcag cggttcagcg gcatcgatga gcatgggcac      480

ctgaccatcg acacggagct ggagggccgc gtgccgcaga ttccgttcgg ctcctccgtg      540

cacattgagc cctacacgga gctgtaccac tactccacct cagtgatcac ttcctcctcc      600

acccgggagt acacggtgac tgagcccgag cgagatgggg catctccttc acgcatctac      660

acttaccagt ggcgccagac catcaccttc caggaatgcg tccacgatga ctcccggcca      720

gccctgccca gcacccagca gctctcggtg gacagcgtgt tcgtcctgta caaccaggag      780

gagaagatct tgcgctatgc tctcagcaac tccattgggc ctgtgaggga aggctcccct      840

gatgctcttc agaatccctg ctacatcggc actcatgggt gtgacaccaa cgcggcctgt      900

cgccctggtc ccaggacaca gttcacctgc gagtgctcca tcggcttccg aggagacggg      960

cgaacctgct atgaggtgga gaaaacccgg tgccagcacg agcgagaaca cattctcggg     1020

gcggcggggg cgacagaccc acagcgaccc attcctccgg ggctgttcgt tcctgagtgc     1080

gatgcgcacg ggcactacgc gcccacccag tgccacggca gcaccggcta ctgctggtgc     1140

gtggatcgcg acggccgcga ggtggagggc accaggacca ggcccgggat gacgcccccg     1200

tgtctgagta cagtggctcc cccgattcac caaggacctg cggtgcctac cgccgtgatc     1260

cccttgcctc ctgggaccca tttactcttt gcccagactg ggaagattga gcgcctgccc     1320

ctggagggaa ataccatgag gaagacagaa gcaaaggcgt tccttcatgt cccggctaaa     1380

gtcatcattg gactggcctt tgactgcgtg gacaagatgg tttactggac ggacatcact     1440

gagccttcca ttgggagagc tagtctacat ggtggagagc caaccaccat cattagacaa     1500

gatcttggaa gtccagaagg tatcgctgtt gatcaccttg gccgcaacat cttctggaca     1560

gactctaacc tggatcgaat agaagtggcg aagctggacg gcacgcagcg ccgggtgctc     1620

tttgagactg acttggtgaa tcccagaggc attgtaacgg attccgtgag agggaacctt     1680

tactggacag actggaacag agataacccc aagattgaaa cttcctacat ggacggcacg     1740

aaccggagga tccttgtgca ggatgacctg ggcttgccca atggactgac cttcgatgcg     1800

ttctcatctc agctctgctg ggtggatgca ggcaccaatc gggcggaatg cctgaacccc     1860

agtcagccca gcagacgcaa ggctctcgaa gggctccagt atccttttgc tgtgacgagc     1920

tacgggaaga atctgtattt cacagactgg aagatgaatt ccgtggttgc tctcgatctt     1980

gcaatttcca aggagacgga tgctttccaa ccccacaagc agacccggct gtatggcatc     2040

accacggccc tgtctcagtg tccgcaaggc cataactact gctcagtgaa caatggcggc     2100

tgcacccacc tatgcttggc caccccaggg agcaggacct gccgttgccc tgacaacacc     2160

ttgggagttg actgtatcga acagaaa                                         2187


<210>  4083
<211>  2817
<212>  DNA
<213>  Homo Sapiens

<400>  4083
ctgcacccag acgagctctt cccacacggg gagtcgtggg gggaccagct cctgcaggaa       60

ggcgacgacg aaagctcagc cgtggtgaag ctggcgaatc ccctgcactt ctacgaagcc      120

cgattcagca acctctacgt gggcaccaac ggcatcatct ccactcagga cttccccagg      180

gaaacgcagt atgtggacta tgatttcccc accgacttcc cggccatcgc cccttttctg      240

gcggacatcg acacgagcca cggcagaggc cgagtcctgt accgagtgaa tgggaaagtg      300

agtggccacc tccacgtggg ccatacaccc gtgcacttca ctgatgtgga cctgcatgcg      360

tatatcgtgg gcaatgatgg cagagcctac acggccatca gccacatccc acagccagca      420

gcccaggccc tcctccccct cacaccaatt ggaggcctgt ttggctggct ctttgcttta      480

gaaaaacctg gctctgagaa cggcttcagc ctcgcaggtg ctgcctttac ccatgacatg      540

gaagttacat tctacccggg agaggagacg gttcgtatca ctcaaactgc tgagggactt      600

gacccagaga actacctgag cattaagacc aacattcaag gccaggtgcc ttacgtccca      660

gcaaatttca cagcccacat ctctccctac aaggagctgt accactactc cgactccact      720

gtgacctcta caagttccag agactactct ctgacttttg gtgcaatcaa ccaaacatgg      780

tcctaccgca tccaccagaa catcacttac caggtgtgca ggcatgcccc cagacacccg      840

tccttcccca ccacccagca gctgaacgtg gaccgggtct ttgccttgta taatgacgaa      900

gaaagagtgc ttagatttgc tgtgaccaat caaattggcc cggtcaaaga agattcagac      960

cccactccgg tgaatccttg ctatgatggg agccacatgt gtgacacaac agcacggtgc     1020

catccaggga caggtgtaga ttacacctgt gagtgcgcat ctgggtacca gggagatgga     1080

cggaactgtg tggatgaaaa tgaatgtgca actggctttc atcgctgtgg ccccaactct     1140

gtatgtatca acttgcctgg aagctacagg tgtgagtgcc ggagtgctta tgagtttgca     1200

gatgaccggc atacttgcat cttgatcacc ccacctgcca acccctgtga ggatggcagt     1260

catacctgtg ctcctgctgg gcaggcccgg tgtgttcacc atggaggcag cacgttcagc     1320

tgtgcctgcc tgcctggtta tgccggcgat gggcaccagt gcactgatgt agatgaatgc     1380

tcagaaaaca gatgtcaccc tgcagctacc tgctacaata ctcctggttc cttctcctgc     1440

cgttgtcaac ccggatatta tggggatgga tttcagtgca tacctgactc cacctcaagc     1500

ctgacaccct gtgaacaaca gcagcgccat gcccaggccc agtatgccta ccctggggcc     1560

cggttccaca tcccccaatg cgacgagcag ggcaacttcc tgcccctaca gtgtcatggc     1620

agcactggtt tctgctggtg cgtggaccct gatggtcatg aagttcctgg tacccagact     1680

ccacctggct ccaccccgcc tcactgtgga ccatcaccag agcccaccca gaggcccccg     1740

accatctgtg agcgctggag ggaaaacctg ctggagcact acggtggcac cccccgggat     1800

gaccagtacg tgccccagtg cgatgacctg ggccacttca tccccctgca gtgccacgga     1860

aagagcgact tctgctggtg tgtggacaaa gatggcagag aggtgcaggg cacccgctcc     1920

cagccaggca ccacccctgc gtgtataccc accgtcgctc cacccatggt ccggcccacg     1980

ccccggccag atgtgacccc tccatctgtg ggcaccttcc tgctctatac tcagggccag     2040

cagattggct acttacccct caatggcacc aggcttcaga aggatgcagc taagaccctg     2100

ctgtctctgc atggctccat aatcgtggga attgattacg actgccggga gaggatggtg     2160

tactggacag atgttgctgg acggacaatc agccgtgccg gtctggaact gggagcagag     2220

cctgagacga tcgtgaattc aggtctgata agccctgaag gacttgccat agaccacatc     2280

cgcagaacaa tgtactggac ggacagtgtc ctggataaga tagagagcgc cctgctggat     2340

ggctctgagc gcaaggtcct cttctacaca gatctggtga atccccgtgc catcgctgtg     2400

gatccaatcc gaggcaactt gtactggaca gactggaata gagaagctcc taaaattgaa     2460

acgtcatctt tagatggaga aaacagaaga attctgatca atacagacat tggattgccc     2520

aatggcttaa cctttgaccc tttctctaaa ctgctctgct gggcagatgc aggaaccaaa     2580

aaactggagt gtacactacc tgatggaact ggacggcgtg tcattcaaaa caacctcaag     2640

taccccttca gcatcgtaag ctatgcagat cacttctacc acacagactg gaggagggat     2700

ggtgttgtat cagtaaataa acatagtggc cagtttactg atgagtatct cccagaacaa     2760

cgatctcacc tctacgggat aactgcagtc tacccctact gcccaacagg aagaaag        2817


<210>  4084
<211>  1899
<212>  DNA
<213>  Homo Sapiens

<400>  4084
cagtatccag ttgtcaacac aaattatggt aaaatccagg gcctaagaac accattaccc       60

agtgagatct tgggtccagt ggagcagtac ttaggggtcc cctatgcctc acccccaact      120

ggagagaggc ggtttcagcc accagaatcc ccatcctcct ggactggcat ccgaaatgct      180

actcagtttt ctgctgtgtg cccccagcac ctggatgaaa gattcttatt gcatgacatg      240

ctgcccatct ggtttaccac cagtttggat actttgatga cctatgttca agatcaaaat      300

gaagactgcc tttacttaaa catctatgtg cccatggaag atgatattca tgaacagaac      360

agtaagaagc ctgttatggt ctatatccat gggggatctt acatggaggg aaccggtaac      420

atgattgatg gcagcatttt ggccagctat gggaacgtca tcgttatcac cattaactac      480

cgtctgggaa tactagggtt tttaagtacc ggtgaccagg cagcaaaagg caactatggg      540

ctcctggatc agattcaagc actgaggtgg attgaggaga atgtcggagc ctttggcggg      600

gaccccaaga gagtgactat ctttggctcg ggggctgggg cctcctgtgt cagcctgttg      660

accctgtccc actactcaga aggtctcttc cagaaggcca tcattcagag cggcactgcc      720

ctgtccagct gggcagtgaa ctaccagccg gccaagtaca ctcggatatt ggcagacaag      780

gtcggctgca acatgctgga caccacggac atggtagaat gtctgaagaa caagaactac      840

aaggagctca tccagcagac catcaccccg gccacctacc acatagcctt tgggccggtg      900

atcgacggcg acgtcatccc agacgacccc cagatcctga tggagcaagg cgagttcctc      960

aactacgaca tcatgctggg cgtcaaccaa ggggaaggcc tgaagttcgt ggacggcatc     1020

gtggataacg aggacggtgt gacgcccaac gactttgact tctccgtgtc caacttcgtg     1080

gacaaccttt acggctaccc tgaagggaaa gacactttgc gggagactat caagttcatg     1140

tacacagact gggccgataa ggaaaacccg gagacgcggc ggaaaaccct ggtggctctc     1200

tttactgacc atcagtgggt ggcccccgcc gtggccaccg ccgacctgca cgcgcagtac     1260

ggctccccca cctacttcta tgccttctat catcactgcc aaagcgaaat gaagcccagc     1320

tgggcagatt cggcccatgg cgatgaagtc ccctatgtct tcggcatccc catgatcggt     1380

cccacagagc tcttcagttg taatttctcc aagaacgacg tcatgctcag tgccgtggtg     1440

atgacctact ggacgaactt cgccaaaact ggtgatccaa accaaccagt tcctcaggat     1500

accaagttca ttcatacaaa acccaatcgc tttgaagaag tggcctggtc caagtataat     1560

cccaaagacc agctctatct gcatattggc ttgaaaccca gagtgagaga tcactaccgg     1620

gcaacgaaag tggctttctg gttggaattg gttcctcatt tgcacaactt gaacgagata     1680

ttccagtatg tttcaacaac cacaaaggtt cctccaccag acatgacatc atttccctat     1740

ggcacccggc gatctcccgc caagatatgg ccaaccacca aacgcccagc aatcactcct     1800

gccaacaatc ccaaacactc taaggaccct cacaaaacag ggcccgagga cacaactgtc     1860

ctcattgaaa ccaaacgaga ttattccacc gaattaagt                            1899


<210>  4085
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  4085
cagtatccag ttgtcaacac aaattatggt aaaatccagg gcctaagaac accattaccc       60

agtgagatct tgggtccagt ggagcagtac ttaggggtcc cctatgcctc acccccaact      120

ggagagaggc ggtttcagcc accagaatcc ccatcctcct ggactggcat ccgaaatgct      180

actcagtttt ctgctgtgtg cccccagcac ctggatgaaa gattcttatt gcatgacatg      240

ctgcccatct ggtttaccac cagtttggat actttgatga cctatgttca agatcaaaat      300

gaagactgcc tttacttaaa catctatgtg cccatggaag atggaaccaa cataaagaga      360

aatgcagacg atataaccag taatgaccat ggtgaagata aagatattca tgaacagaac      420

agtaagaagc ctgttatggt ctatatccat gggggatctt acatggaggg aaccggtaac      480

atgattgatg gcagcatttt ggccagctat gggaacgtca tcgttatcac cattaactac      540

cgtctgggaa tactaggtat gcaagaggca cgtttgtgtg ggagctcaaa aatgtttaat      600

tattttaaat ctcctttcac taatttaata aattttttt                             639


<210>  4086
<211>  2937
<212>  DNA
<213>  Homo Sapiens

<400>  4086
atgaagatgg caagcacccg ctgcaagctg gccaggtacc tggaggacct ggaggatgtg       60

gacttgaaga aatttaagat gcacttagag gactatcctc cccagaaggg ctgcatcccc      120

ctcccgaggg gtcagacaga gaaggcagac catgtggatc tagccacgct aatgatcgac      180

ttcaatgggg aggagaaggc gtgggccatg gccgtgtgga tcttcgctgc gatcaacagg      240

agagaccttt atgagaaagc aaaaagagat gagccgaagt ggggttcaga taatgcacgt      300

gtttcgaatc ccactgtgat atgccaggaa gacagcattg aagaggagtg gatgggttta      360

ctggagtacc tttcgagaat ctctatttgt aaaatgaaga aagattaccg taagaagtac      420

agaaagtacg tgagaagcag attccagtgc attgaagaca ggaatgcccg tctgggtgag      480

agtgtgagcc tcaacaaacg ctacacacga ctgcgtctca tcaaggagca ccggagccag      540

caggagaggg agcaggagct tctggccatc ggcaagacca agacgtgtga gagccccgtg      600

agtcccatta agatggagtt gctgtttgac cccgatgatg agcattctga gcctgtgcac      660

actgtggtgt tccagggggc ggcagggatt gggaaaacaa tcctggccag gaagatgatg      720

ttggactggg cgtcggggac actctaccaa gacaggtttg actatctgtt ctatatccac      780

tgtcgggagg tgagccttgt gacacagagg agcctggggg acctgatcat gagctgctgc      840

cccgacccaa acccacccat ccacaagatc gtgagaaaac cctccagaat cctcttcctc      900

atggacggct tcgatgagct gcaaggtgcc tttgacgagc acataggacc gctctgcact      960

gactggcaga aggccgagcg gggagacatt ctcctgagca gcctcatcag aaagaagctg     1020

cttcccgagg cctctctgct catcaccacg agacctgtgg ccctggagaa actgcagcac     1080

ttgctggacc atcctcggca tgtggagatc ctgggtttct ccgaggccaa aaggaaagag     1140

tacttcttca agtacttctc tgatgaggcc caagccaggg cagccttcag tctgattcag     1200

gagaacgagg tcctcttcac catgtgcttc atccccctgg tctgctggat cgtgtgcact     1260

ggactgaaac agcagatgga gagtggcaag agccttgccc agacatccaa gaccaccacc     1320

gcggtgtacg tcttcttcct ttccagtttg ctgcagcccc ggggagggag ccaggagcac     1380

ggcctctgcg cccacctctg ggggctctgc tctttggctg cagatggaat ctggaaccag     1440

aaaatcctgt ttgaggagtc cgacctcagg aatcatggac tgcagaaggc ggatgtgtct     1500

gctttcctga ggatgaacct gttccaaaag gaagtggact gcgagaagtt ctacagcttc     1560

atccacatga ctttccagga gttctttgcc gccatgtact acctgctgga agaggaaaag     1620

gaaggaagga cgaacgttcc agggagtcgt ttgaagcttc ccagccgaga cgtgacagtc     1680

cttctggaaa actatggcaa attcgaaaag gggtatttga tttttgttgt acgtttcctc     1740

tttggcctgg taaaccagga gaggacctcc tacttggaga agaaattaag ttgcaagatc     1800

tctcagcaaa tcaggctgga gctgctgaaa tggattgaag tgaaagccaa agctaaaaag     1860

ctgcagatcc agcccagcca gctggaattg ttctactgtt tgtacgagat gcaggaggag     1920

gacttcgtgc aaagggccat ggactatttc cccaagattg agatcaatct ctccaccaga     1980

atggaccaca tggtttcttc cttttgcatt gagaactgtc atcgggtgga gtcactgtcc     2040

ctggggtttc tccataacat gcccaaggag gaagaggagg aggaaaagga aggccgacac     2100

cttgatatgg tgcagtgtgt cctcccaagc tcctctcatg ctgcctgttc tcatgggttg     2160

gggcgctgtg gcctctcgca tgagtgctgc ttcgacatct ccttggtcct cagcagcaac     2220

cagaagctgg tggagctgga cctgagtgac aacgccctcg gtgacttcgg aatcagactt     2280

ctgtgtgtgg gactgaagca cctgttgtgc aatctgaaga agctctggtt ggtcagctgc     2340

tgcctcacat cagcatgttg tcaggatctt gcatcagtat tgagcaccag ccattccctg     2400

accagactct atgtggggga gaatgccttg ggagactcag gagtcgcaat tttatgtgaa     2460

aaagccaaga atccacagtg taacctgcag aaactggggt tggtgaattc tggccttacg     2520

tcagtctgtt gttcagcttt gtcctcggta ctcagcacta atcagaatct cacgcacctt     2580

tacctgcgag gcaacactct cggagacaag gggatcaaac tactctgtga gggactcttg     2640

caccccgact gcaagcttca ggtgttggaa ttagacaact gcaacctcac gtcacactgc     2700

tgctgggatc tttccacact tctgacctcc agccagagcc tgcgaaagct gagcctgggc     2760

aacaatgacc tgggcgacct gggggtcatg atgttctgtg aagtgctgaa acagcagagc     2820

tgcctcctgc agaacctggg gttgtctgaa atgtatttca attatgagac aaaaagtgcg     2880

ttagaaacac ttcaagaaga aaagcctgag ctgaccgtcg tctttgagcc ttcttgg        2937


<210>  4087
<211>  2799
<212>  DNA
<213>  Homo Sapiens

<400>  4087
gagctgctgt tgccccagga gacgactgtg gagctgagct gtggagtggg gccactgcaa       60

gtgatcctgg gcccagagca ggctgcagtg ctaaactgta gcctgggggc tgctgccgct      120

ggacccccca ccagggtgac ctggagcaag gatggggaca ccctgctgga gcacgaccac      180

ttacacctgc tgcccaatgg ttccctgtgg ctgtcccagc cactagcacc caatggcagt      240

gacgagtcag tccctgaggc tgtgggggtc attgaaggca actattcgtg cctagcccac      300

ggccccctcg gagtgctggc cagccagact gctgtcgtca agcttgccac actcgcagac      360

ttctctctgc acccggagtc tcagacggtg gaggagaacg ggacagctcg ctttgagtgc      420

cacattgaag ggctgccagc tcccatcatt acttgggaga aggaccaggt gacattgcct      480

gaggagcctc ggctcatcgt gcttcccaac ggcgtccttc agatcctgga tgttcaggag      540

agtgatgcag gcccctaccg ctgcgtggcc accaactcag ctcgccagca cttcagccag      600

gaggccctac tcagtgtggc ccacagaggg tccctggcgt ccaccagggg gcaggacgtg      660

gtcattgtgg cagccccaga gaacaccaca gtggtgtctg gccagagtgt ggtgatggaa      720

tgtgtggcct cagctgaccc cacccctttt gtgtcctggg tccgacaaga cgggaagccc      780

atctccacag atgtcatcgt cctgggccgc accaacctac taattgccaa cgcgcagccc      840

tggcactccg gcgtctatgt ctgccgcgcc aacaagcccc gcacgcgcga cttcgccact      900

gcagccgctg agctccgtgt gctggcggct cccgccatca ctcaggcgcc cgaggcgctg      960

tcgcggacgc gggcgagcac agcgcgcttc gtgtgccgcg cgtcggggga gccgcggcca     1020

gcgctgcgct ggctgcacaa cggggcgccg ctgcggccca acgggcgcgt caaggtccag     1080

ggcggcggtg gcagcctggt catcacacag atcggcctgc aggacgccgg ctactaccag     1140

tgcgtggctg agaacagcgc gggaatggcg tgcgctgccg cgtcgctggc cgtggtggtg     1200

cgcgaggggc tgcccagcgc ccccacgcgg gtcactgcta cgccactgag cagctccgct     1260

gtgttggtgg cctgggagcg gcccgagatg cacagcgagc agatcatcgg cttctctctc     1320

cactaccaga aggcacgggg catggacaat gtggaatacc agtttgcagt gaacaacgac     1380

accacagaac tacaggttcg ggacctggaa cccaacacag attatgagtt ctacgtggtg     1440

gcctactccc agctgggagc cagccgcacc tccaccccag cactggtgca cacactggat     1500

gatgtcccca gtgcagcacc ccagctctcc ctgtccagcc ccaacccttc ggacatcagg     1560

gtggcgtggc tgcccctgcc ccccagcctg agcaatgggc aggtggtgaa gtacaagata     1620

gaatacggtt tgggaaagga agatcagatt ttctctactg aggtgcgagg aaatgagaca     1680

cagcttatgc tgaactcgct tcagccaaac aaggtgtatc gagtacggat ttcggctggt     1740

acagcagccg gcttcggggc cccctcccag tggatgcatc acaggacgcc cagtatgcac     1800

aaccagagcc atgtcccttt tgcccctgca gagttgaagg tgcaggcaaa gatggagtcc     1860

ctggtcgtgt catggcagcc accccctcac cccacccaga tctctggcta caaactatat     1920

tggcgggagg tgggggctga ggaggaggcc aatggcgatc gcctgccagg gggccgtgga     1980

gaccaggctt gggatgtggg gcctgtccgg ctcaagaaga aagtgaagca gtatgagctg     2040

acccagctag tccctggccg gctgtacgag gtgaagctcg tggctttcaa caaacatgag     2100

gatggctatg cagcagtgtg gaagggcaag acggagaagg cgccggcacc agacatgcct     2160

atccagaggg gaccacccct gcctccagcc cacgtccatg cggaatcaaa cagctccaca     2220

tccatctggc ttcggtggaa aaagccagat ttcaccacag tcaagattgt caactacact     2280

gtgcgcttca gcccctgggg gctcaggaat gcctccctgg tcacctatta caccagttct     2340

ggagaagaca tcctcattgg cggcttgaag ccattcacca aatacgagtt tgcagtgcag     2400

tctcacggcg tggacatgga tgggcctttc ggctctgtgg tggagcgctc caccctgcct     2460

gaccggccct ccacaccccc atccgacctg cgactgagcc ccctgacacc gtccacggtt     2520

cggctgcact ggtgcccccc cacagagccc aacggggaga tcgtggagta tctgatcctg     2580

tacagcagca accacacgca gcctgagcac cagtggacct tgctcaccac gcagggaaac     2640

atcttcagtg ctgaggtcca tggcctggag agcgacactc ggtacttctt caagatgggg     2700

gcgcgcacag aggtgggacc tgggcctttc tcccgcctgc aggatgtgat cacgctccag     2760

gagaagctgt cagactcgct ggacatgcac tcagtcacg                            2799


<210>  4088
<211>  3630
<212>  DNA
<213>  Homo Sapiens

<400>  4088
ttgcagtgtc gagatggcta tgaaccctgt gtaaatgaag gaatgtgtgt tacctaccac       60

aatggcacag gatactgcaa atgtccagaa ggcttcttgg gggaatattg tcaacatcga      120

gacccctgtg agaagaaccg ctgccagaat ggtgggactt gtgtggccca ggccatgctg      180

gggaaagcca cgtgccgatg tgcctcaggg tttacaggag aggactgcca gtactcaaca      240

tctcatccat gctttgtgtc tcgaccctgc ctgaatggcg gcacatgcca tatgctcagc      300

cgggatacct atgagtgcac ctgtcaagtc gggtttacag gtaaggagtg ccaatggacg      360

gatgcctgcc tgtctcatcc ctgtgcaaat ggaagtacct gtaccactgt ggccaaccag      420

ttctcctgca aatgcctcac aggcttcaca gggcagaaat gtgagactga tgtcaatgag      480

tgtgacattc caggacactg ccagcatggt ggcacctgcc tcaacctgcc tggttcctac      540

cagtgccagt gccctcaggg cttcacaggc cagtactgtg acagcctgta tgtgccctgt      600

gcaccctcac cttgtgtcaa tggaggcacc tgtcggcaga ctggtgactt cacttttgag      660

tgcaactgcc ttccaggttt tgaagggagc acctgtgaga ggaatattga tgactgccct      720

aaccacaggt gtcagaatgg aggggtttgt gtggatgggg tcaacactta caactgccgc      780

tgtcccccac aatggacagg acagttctgc acagaggatg tggatgaatg cctgctgcag      840

cccaatgcct gtcaaaatgg gggcacctgt gccaaccgca atggaggcta tggctgtgta      900

tgtgtcaacg gctggagtgg agatgactgc agtgagaaca ttgatgattg tgccttcgcc      960

tcctgtactc caggctccac ctgcatcgac cgtgtggcct ccttctcttg catgtgccca     1020

gaggggaagg caggtctcct gtgtcatctg gatgatgcat gcatcagcaa tccttgccac     1080

aagggggcac tgtgtgacac caacccccta aatgggcaat atatttgcac ctgcccacaa     1140

ggctacaaag gggctgactg cacagaagat gtggatgaat gtgccatggc caatagcaat     1200

ccttgtgagc atgcaggaaa atgtgtgaac acggatggcg ccttccactg tgagtgtctg     1260

aagggttatg caggacctcg ttgtgagatg gacatcaatg agtgccattc agacccctgc     1320

cagaatgatg ctacctgtct ggataagatt ggaggcttca catgtctgtg catgccaggt     1380

ttcaaaggtg tgcattgtga attagaaata aatgaatgtc agagcaaccc ttgtgtgaac     1440

aatgggcagt gtgtggataa agtcaatcgt ttccagtgcc tgtgtcctcc tggtttcact     1500

gggccagttt gccagattga tattgatgac tgttccagta ctccgtgtct gaatggggca     1560

aagtgtatcg atcacccgaa tggctatgaa tgccagtgtg ccacaggttt cactggtgtg     1620

ttgtgtgagg agaacattga caactgtgac cccgatcctt gccaccatgg tcagtgtcag     1680

gatggtattg attcctacac ctgcatctgc aatcccgggt acatgggcgc catctgcagt     1740

gaccagattg atgaatgtta cagcagccct tgcctgaacg atggtcgctg cattgacctg     1800

gtcaatggct accagtgcaa ctgccagcca ggcacgtcag gggttaattg tgaaattaat     1860

tttgatgact gtgcaagtaa cccttgtatc catggaatct gtatggatgg cattaatcgc     1920

tacagttgtg tctgctcacc aggattcaca gggcagagat gtaacattga cattgatgag     1980

tgtgcctcca atccctgtcg caagggtgca acatgtatca acggtgtgaa tggtttccgc     2040

tgtatatgcc ccgagggacc ccatcacccc agctgctact cacaggtgaa cgaatgcctg     2100

agcaatccct gcatccatgg aaactgtact ggaggtctca gtggatataa gtgtctctgt     2160

gatgcaggct gggttggcat caactgtgaa gtggacaaaa atgaatgcct ttcgaatccg     2220

tgccagaatg gaggaacttg tgacaatctg gtgaatggat acaggtgtac ttgcaagaag     2280

ggctttaaag gctataactg ccaggtgaat attgatgaat gtgcctcaaa tccatgcctg     2340

aaccaaggaa cctgctttga tgacataagt ggctacactt gccactgtgt gctgccatac     2400

acaggcaaga attgtcagac agtattggct ccctgttccc caaacccttg tgagaatgct     2460

gctgtttgca aagagtcacc aaattttgag agttatactt gcttgtgtgc tcctggctgg     2520

caaggtcagc ggtgtaccat tgacattgac gagtgtatct ccaagccctg catgaaccat     2580

ggtctctgcc ataacaccca gggcagctac atgtgtgaat gtccaccagg cttcagtggt     2640

atggactgtg aggaggacat tgatgactgc cttgccaatc cttgccagaa tggaggttcc     2700

tgtatggatg gagtgaatac tttctcctgc ctctgccttc cgggtttcac tggggataag     2760

taccagacag acatgaatga gtgtctgagt gaaccctgta agaatggagg gacctgctct     2820

gactacgtca acagttacac ttgcaagtgc caggcaggat ttgatggagt ccattgtgag     2880

aacaacatca atgagtgcac tgagagctcc tgtttcaatg gtggcacatg tgttgatggg     2940

attaactcct tctcttgctt gtgccctgtg ggtttcactg gatccttctg cctccatgag     3000

atcaatgaat gcagctctca tccatgcctg aatgagggaa cgtgtgttga tggcctgggt     3060

acctaccgct gcagctgccc cctgggctac actgggaaaa actgtcagac cctggtgaat     3120

ctctgcagtc ggtctccatg taaaaacaaa ggtacttgcg ttcagaaaaa agcagagtcc     3180

cagtgcctat gtccatctgg atgggctggt gcctattgtg acgtgcccaa tgtctcttgt     3240

gacatagcag cctccaggag aggtgtgctt gttgaacact tgtgccagca ctcaggtgtc     3300

tgcatcaatg ctggcaacac gcattactgt cagtgccccc tgggctatac tgggagctac     3360

tgtgaggagc aactcgatga gtgtgcgtcc aacccctgcc agcacggggc aacatgcagt     3420

gacttcattg gtggatacag atgcgagtgt gtcccaggct atcagggtgt caactgtgag     3480

tatgaagtgg atgagtgcca gaatcagccc tgccagaatg gaggcacctg tattgacctt     3540

gtgaaccatt tcaagtgctc ttgcccacca ggcactcggg gtatgaaatc atccttatcc     3600

attttccatc cagggcattg tcttaagtta                                      3630


<210>  4089
<211>  708
<212>  DNA
<213>  Homo Sapiens

<400>  4089
atgtgtgtta cctaccacaa tggcacagga tactgcaaat gtccagaagg cttcttgggg       60

gaatattgtc aacatcgaga cccctgtgag aagaaccgct gccagaatgg tgggacttgt      120

gtggcccagg ccatgctggg gaaagccacg tgccgatgtg cctcagggtt tacaggagag      180

gactgccagt actcgacatc tcatccatgc tttgtgtctc gaccttgcct gaatggcggc      240

acatgccata tgctcagccg ggatacctat gagtgcacct gtcaagtcgg gtttacaggt      300

aaggagtgcc aatggaccga tgcctgcctg tctcatccct gtgcaaatgg aagtacctgt      360

accactgtgg ccaaccagtt ctcctgcaaa tgcctcacag gcttcacagg gcagaagtgt      420

gagactgatg tcaatgagtg tgacattcca ggacactgcc agcatggtgg cacctgcctc      480

aacctgcctg gttcctacca gtgccagtgc cttcagggct tcacaggcca gtactgtgac      540

agcctgtatg tgccctgtgc accctcgcct tgtgtcaatg gaggcacctg tcggcagact      600

ggtgacttca cttttgagtg caactgcctt ccagaaacag tgagaagagg aacagagctc      660

tgggaaagag acagggaagt ctggaatgga aaagaacacg atgagaat                   708


<210>  4090
<211>  4272
<212>  DNA
<213>  Homo Sapiens

<400>  4090
agagggctgc tgtgtgggag tttcccagaa ccctgtgcca atggaggcac ctgcctgagc       60

ctgtctctgg gacaagggac ctgccagtgt gcccctggct tcctgggtga gacgtgccag      120

tttcctgacc cctgccagaa cgcccagctc tgccaaaatg gaggcagctg ccaagccctg      180

cttcctgctc ccctagggct ccccagctct ccctctccat tgacacccag cttcttgtgc      240

acttgcctcc ctggcttcac tggtgagaga tgccaggcca agcttgaaga cccttgtcct      300

ccctccttct gttccaaaag gggccgctgc cacatccagg cctcgggccg cccacagtgc      360

tcctgcatgc ctggatggac aggtgagcag tgccagcttc gggacttctg ttcagccaac      420

ccatgtgtta atggaggggt gtgtctggcc acataccccc agatccagtg ccactgccca      480

ccgggcttcg agggccatgc ctgtgaacgt gatgtcaacg agtgcttcca ggacccagga      540

ccctgcccca aaggcacctc ctgccataac accctgggct ccttccagtg cctctgccct      600

gtggggcagg agggtccacg ttgtgagctg cgggcaggac cctgccctcc taggggctgt      660

tcgaatgggg gcacctgcca gctgatgcca gagaaagact ccacctttca cctctgcctc      720

tgtcccccag gtttcatagg cccagactgt gaggtgaatc cagacaactg tgtcagccac      780

cagtgtcaga atgggggcac ttgccaggat gggctggaca cctacacctg cctctgccca      840

gaaacctgga caggctggga ctgctccgaa gatgtggatg agtgtgagac ccagggtccc      900

cctcactgca gaaacggggg cacctgccag aactctgctg gtagctttca ctgcgtgtgt      960

gtgagtggct ggggcggcac aagctgtgag gagaacctgg atgactgtat tgctgccacc     1020

tgtgccccgg gatccacctg cattgaccgg gtgggctctt tctcctgcct ctgcccacct     1080

ggacgcacag gactcctgtg ccacttggaa gacatgtgtc tgagccagcc gtgccatggg     1140

gatgcccaat gcagcaccaa ccccctcaca ggctccacac tctgcctgtg tcagcctggc     1200

tattcggggc ccacctgcca ccaggacctg gacgagtgtc tgatggccca gcaaggccca     1260

agtccctgtg aacatggcgg ttcctgcctc aacactcctg gctccttcaa ctgcctctgt     1320

ccacctggct acacaggctc ccgttgtgag gctgatcaca atgagtgcct ctcccagccc     1380

tgccacccag gaagcacctg tctggaccta cttgccacct tccactgcct ctgcccgcca     1440

ggcttagaag ggcagctctg tgaggtggag accaacgagt gtgcctcagc tccctgcctg     1500

aaccacgcgg attgccatga cctgctcaac ggcttccagt gcatctgcct gcctggattc     1560

tccggcaccc gatgtgagga ggatatcgat gagtgcagaa gctctccctg tgccaatggt     1620

gggcagtgcc aggaccagcc tggagccttc cactgcaagt gtctcccagg ctttgaaggg     1680

ccacgctgtc aaacagaggt ggatgagtgc ctgagtgacc catgtcccgt tggagccagc     1740

tgccttgatc ttccaggagc cttcttttgc ctctgcccct ctggtttcac aggccagctc     1800

tgtgaggttc ccctgtgtgc tcccaacctg tgccagccca agcagatatg taaggaccag     1860

aaagacaagg ccaactgcct ctgtcctgat ggaagccctg gctgtgcccc acctgaggac     1920

aactgcacct gccaccacgg gcactgccag agatcctcat gtgtgtgtga cgtgggttgg     1980

acggggccag agtgtgaggc agagctaggg ggctgcatct ctgcaccctg tgcccatggg     2040

gggacctgct acccccagcc ctctggctac aactgcacct gccctacagg ctacacagga     2100

cccacctgta gtgaggagat gacagcttgt cactcagggc catgtctcaa tggcggctcc     2160

tgcaacccta gccctggagg ctactactgc acctgccctc caagccacac agggccccag     2220

tgccaaacca gcactgacta ctgtgtgtct gccccgtgct tcaatggggg tacctgtgtg     2280

aacaggcctg gcaccttctc ctgcctctgt gccatgggct tccagggccc gcgctgtgag     2340

ggaaagctcc gccccagctg tgcagacagc ccctgtagga atagggcaac ctgccaggac     2400

agccctcagg gtccccgctg cctctgcccc actggctaca ccggaggcag ctgccagact     2460

ctgatggact tatgtgccca gaagccctgc ccacgcaatt cccactgcct ccagactggg     2520

ccctccttcc actgcttgtg cctccaggga tggaccgggc ctctctgcaa ccttccactg     2580

tcctcctgcc agaaggctgc actgagccaa ggcatagacg tctcttccct ttgccacaat     2640

ggaggcctct gtgtcgacag cggcccctcc tatttctgcc actgcccccc tggattccaa     2700

ggcagcctgt gccaggatca cgtgaaccca tgtgagtcca ggccttgcca gaacggggcc     2760

acctgcatgg cccagcccag tgggtatctc tgccagtgtg ccccaggcta cgatggacag     2820

aactgctcaa aggaactcga tgcttgtcag tcccaaccct gtcacaacca tggaacctgt     2880

actcccaaac ctggaggctt ccactgtgcc tgccctccag gctttgtggg gctacgctgt     2940

gagggagacg tggacgagtg tctggaccag ccctgccacc ccacaggcac tgcagcctgc     3000

cactctctgg ccaatgcctt ctactgccag tgtctgcctg gacacacagg ccagtggtgt     3060

gaggtggaga tagacccctg ccacagccaa ccctgctttc atggagggac ctgtgaggcc     3120

acagcaggat cacccctggg tttcatctgc cactgcccca agggttttga aggccccacc     3180

tgcagccaca gggccccttc ctgcggcttc catcactgcc accacggagg cctgtgtctg     3240

ccctccccta agccaggctt cccaccacgc tgtgcctgcc tcagtggcta tgggggtcct     3300

gactgcctga ccccaccagc tcctaaaggc tgtggccctc cctccccatg cctatacaat     3360

ggcagctgct cagagaccac gggcttgggg ggcccaggct ttcgatgctc ctgccctcac     3420

agctctccag ggccccggtg tcagaaaccc ggagccaagg ggtgtgaggg cagaagtgga     3480

gatggggcct gcgatgctgg ctgcagtggc ccgggaggaa actgggatgg aggggactgc     3540

tctctgggag tcccagaccc ctggaagggc tgcccctccc actctcggtg ctggcttctc     3600

ttccgggacg ggcagtgcca cccacagtgt gactctgaag agtgtctgtt tgatggctac     3660

gactgtgaga cccctccagc ctgcactcca gcctatgacc agtactgcca tgatcacttc     3720

cacaacgggc actgtgagaa aggctgcaac actgcagagt gtggctggga tggaggtgac     3780

tgcaggcctg aagatgggga cccagagtgg gggccctccc tggccctgct ggtggtactg     3840

agccccccag ccctagacca gcagctgttt gccctggccc gggtgctgtc cctgactctg     3900

agggtaggac tctgggtaag gaaggatcgt gatggcaggg acatggtgta cccctatcct     3960

ggggcccggg ctgaagaaaa gctaggagga actcgggacc ccacctatca ggagagagca     4020

gcccctcaaa cgcagcccct gggcaaggag accgactccc tcagtgctgg gtttgtggtg     4080

gtcatgggtg tggatttgtc ccgctgtggc cctgaccacc cggcatcccg ctgtccctgg     4140

gaccctgggc ttctactccg cttccttgct gcgatggctg cagtgggagc cctggagccc     4200

ctgctgcctg gaccactgct ggctgtccac cctcatgcag ggaccgcacc ccctgccaac     4260

cagcttccct gg                                                         4272


<210>  4091
<211>  3099
<212>  DNA
<213>  Homo Sapiens

<400>  4091
cagttggcga ttcctgcctc cgttccccgg ggcttctggg ccctgcctga aaacctgacg       60

gtggtggagg gggcctcagt ggagctgcgt tgtggggtca gcacccctgg cagtgcggtg      120

caatgggcca aagatgggct gctcctgggc cccgacccca ggatcccagg cttcccgagg      180

taccgcctgg aaggggaccc tgctagaggt gaattccacc tgcacatcga ggcctgtgac      240

ctcagcgatg acgcggagta tgagtgccag gtcggccgct ctgagatggg gcccgagctc      300

gtgtctccca gagtgatcct ctccatcctg gttcctccca agctgctcct gctgacccca      360

gaggcaggca ccatggtcac ctgggtagct gggcaggagt acgtggtcaa ctgtgtgtct      420

ggggacgcga agccagcacc tgacatcacc attctcctga gtggacagac aatatctgac      480

atctctgcaa acgtgaacga gggctcccag cagaaactct tcactgtgga ggccacagcc      540

agggtgacac cccggagctc agataatagg cagttgctgg tctgtgaggc gtctagccca      600

gcactggagg cccccatcaa ggcctcattc accgtgaatg ttctgttccc tccaggaccc      660

cctgtcatcg agtggccagg cctggatgag gggcacgtgc gggcaggaca gagcttggag      720

ctgccgtgcg tggcccgagg gggtaatccc ttagccacac tgcagtggct gaagaatggc      780

cagccggtgt ccacagcgtg gggcacagag cacacccagg cggtggcccg cagtgtgctg      840

gtgatgaccg tgaggccaga agaccatgga gcgcagctca gctgcgaggc ccacaacagc      900

gtgtctgcag ggacccagga gcacggcatc acactgcagg tcacctttcc ccctagtgcc      960

attattatct tgggatctgc atcccagact gagaacaaga acgtgacact ctcctgtgtc     1020

agcaagtcca gtcgcccgcg ggttctgcta cgatggtggc tgggctggcg gcagctgctg     1080

cccatggagg agacagtcat ggatggactg catggcggtc acatctccat gtccaacctg     1140

acattcctgg cgcggcggga ggacaacggt ctgaccctca catgtgaggc cttcagtgaa     1200

gccttcacca aggagacctt caagaagtcg ctcatcctga acgtaaaata tcccgcccag     1260

aaactgtgga ttgagggtcc cccagagggc cagaagctcc gggctgggac ccgggtgagg     1320

ctggtgtgtt tggctatcgg gggcaaccca gagccctccc tcatgtggta caaggactcg     1380

cgcaccgtga ccgagtcgcg gctgccgcag gagtcgcggc gcgtgcatct cggcagcgtg     1440

gagaaatctg ggagcacctt ctcccgagag ctggtgctgg tcacagggcc gtcggacaac     1500

caggccaagt tcacgtgcaa ggctggacag ctcagcgcgt ccacgcagct ggcggtgcag     1560

tttcccccaa ctaacgtgac gatcctggcc aacgcatccg cactgcgccc gggagacgcc     1620

ttaaacttga catgcgtcag cgtcagcagc aatccgccgg tcaacttgtc ctgggacaag     1680

gaaggggaga ggctggaggg cgtggccgcc ccaccccgga gagccccatt caaaggctcc     1740

gccgccgcca ggagcgtcct tctgcaagtg tcatcccgcg atcatggcca gcgcgtgacc     1800

tgccgcgccc acagcgccga gctccgcgaa accgtgagct ccttctatcg cctcaacgta     1860

ctgtaccgtc cagagttcct gggggagcag gtgctggtgg tgaccgcggt ggagcagggc     1920

gaggcgttgc tgcccgtgtc cgtgtccgct aaccccgccc ccgaggcctt caactggacc     1980

ttccgcggct atcgcctcag tccagcgggc ggcccccggc atcgcatcct gtccagcggg     2040

gctctgcatc tgtggaatgt gacccgcgcg gacgacggcc tctatcagct gcactgccag     2100

aactctgagg gcaccgcgga agcgcggctg cggctggacg tgcactatgc tcccaccatc     2160

cgtgccctcc aggaccccac tgaggtgaac gtcgggggtt ctgtggacat agtctgcact     2220

gtcgatgcca atcccatcct cccgggcatg ttcaactggg agagactggg agaagatgag     2280

gaggaccaga gcctggatga catggagaag atatccaggg gaccaacggg gcgcctgcgg     2340

attcaccatg ccaaactggc ccaggctggc gcttaccagt gcattgtgga caatggggtg     2400

gcgcctccag cacgacggct gctccgtctt gttgtcagat ttgcccccca ggtggagcac     2460

cccactcccc taactaaggt ggctgcagct ggagacagca ccagttctgc caccctccac     2520

tgccgtgccc gaggtgtccc caacatcgtt ttcacttgga caaaaaacgg ggtccctctg     2580

gatctccaag atcccaggta cacggagcac acataccacc agggtggtgt ccacagcagc     2640

ctcctgacca ttgccaacgt gtctgccgcc caggattacg ccctcttcac atgtacagcc     2700

accaacgccc ttggctcgga ccaaaccaac attcaacttg tcagcatcag ccgccctgac     2760

cctccatcag gattaaaggt tgtgagtctg accccacact ccgtggggct ggagtggaag     2820

cctggctttg atgggggcct gccacagagg ttctgcatca ggtatgaggc cctggggact     2880

ccagggttcc actatgtgga tgtcgtacca ccccaggcca ccaccttcac gctgactggt     2940

ctacagcctt ctacaagata cagggtctgg ctgctggcca gtaatgcctt gggggacagt     3000

ggactggctg acaaagggac ccagcttccc atcactaccc caggtctcca ccagccttct     3060

ggagaacctg aagaccagct gcccacagag ccaccttca                            3099


<210>  4092
<211>  1638
<212>  DNA
<213>  Homo Sapiens

<400>  4092
gaatttgacg ggagatggcc caggcagatc gtatccagca taggactatg ccgttacgga       60

ggcagaatag actgctgctg gggctgggct aggcaatctt ggggtcaatg ccagccggtt      120

tgccaaccga gatgcaaaca cggcgaatgc ataggcccga ataaatgtaa gtgccatccc      180

ggttatgcgg ggaaaacctg caatcaagat cttaatgagt gcggcctaaa acctcgtcct      240

tgcaaacatc gttgcatgaa tacttacggc tcttacaaat gttattgctt aaatggctat      300

atgcttatgc cagatggtag ttgttcaagt gcactaacgt gcagcatggc taactgtcaa      360

tatggctgcg atgtcgtaaa aggccaaatc agatgtcagt gcccctctcc cggtcttcag      420

ttagctcccg atggaaggac ttgtgtcgat gtagatgagt gtgctacagg tcgtgcctcc      480

tgcccacgtt ttaggcaatg cgttaatacg tttggttcat atatttgtaa gtgccataag      540

ggcttcgatt tgatgtacat tggaggcaaa taccagtgtc atgacattga tgaatgctcc      600

ctagggcaat atcagtgctc ttcctttgcg aggtgttaca acatcagagg tagttataag      660

tgcaagtgta aggaggggta ccaaggcgac gggcttactt gcgtctacat acccaaagta      720

atgatcgaac ccagcggccc catacatgta ccaaaaggta atggcacgat attaaagggg      780

gacactggga ataataactg gatacccgat gtgggatcaa catggtggcc cccgaaaaca      840

ccatatatac caccgataat aacgaacaga cctacttcta agccgacgac ccgtcccact      900

ccaaaaccga ctcccatccc aacccctccc cctccccctc cacttcccac agagctacgt      960

acacctttac ctccgacgac acccgagcgt cctacgactg ggttgacgac aatagcaccg     1020

gctgcgagta caccgcccgg cgggatcact gtcgacaatc gtgtgcagac ggaccctcag     1080

aaacccagag gagatgtatt tataccacgt caaccgtcca acgacctatt cgaaatattt     1140

gaaatagaga ggggcgtcag tgcagatgat gaagccaaag acgaccccgg cgttttggtc     1200

cattcatgca atttcgatca tggcttatgt gggtggatta gagagaaaga caatgacctt     1260

cactgggaac ccataaggga cccggctggg gggcagtact tgactgtgag tgccgcgaaa     1320

gctcctgggg ggaaggcagc ccgtctggtc ctgccattag gaaggctgat gcattccggt     1380

gacctatgtc tatcctttcg tcataaggtg acagggcttc acagtggaac tctacaagtc     1440

tttgtgcgta agcacggcgc acacggcgct gcgctatggg gcaggaacgg gggacatgga     1500

tggaggcaaa ctcaaatcac cctaaggggt gccgatatta aatctgtggt attcaaaggg     1560

gagaaaaggc gtgggcacac gggggaaatt ggccttgatg acgtgtccct gaagaaaggt     1620

cactgcagcg aagaaagg                                                   1638


<210>  4093
<211>  585
<212>  DNA
<213>  Homo Sapiens

<400>  4093
cagaacgagc caaggattgt caccagtgaa gaggtcatta ttcgagacag ccctgttctc       60

cctgtcaccc tgcagtgtaa cctcacctcc agctctcaca cccttacata cagctactgg      120

acaaagaatg gggtggaact gagtgccact cgtaagaatg ccagcaacat ggagtacagg      180

atcaataagc cgagagctga ggattcaggc gaataccact gcgtatatca ctttgtcagc      240

gctcctaaag caaacgccac cattgaagtg aaagccgctc ctgacatcac tggccataaa      300

cggagtgaga acaagaatga agggcaggat gccactatgt attgcaagtc agttggctac      360

ccccacccag actggatatg gcgcaagaag gagaacggga tgcccatgga cattgtcaat      420

acctctggcc gcttcttcat catcaacaag gaaaattaca ctgagttgaa cattgtgaac      480

ctgcagatca cggaagaccc tggcgagtat gaatgtaatg ccaccaacgc cattggctcc      540

gcctctgttg tcactgtcct cagggtgcgg agccacctgg cccca                      585


<210>  4094
<211>  3093
<212>  DNA
<213>  Homo Sapiens

<400>  4094
cagatgatta gtgcactgga agtacctctt gatccaaaac ttcttgaaga cttggtacag       60

cctccaacca tcacccaaca gtctccaaaa gattacatta ttgaccctcg ggagaatatt      120

gtaatccagt gtgaagccaa agggaaaccg cccccaagct tttcctggac ccgtaatggg      180

actcattttg acatcgataa agaccctctg gtcaccatga agcctggcac aggaacgctc      240

ataattaaca tcatgagcga agggaaagct gagacctatg aaggagtcta tcagtgtaca      300

gcaaggaacg aacgcggagc tgcagtttct aataacattg ttgtccgccc atccagatca      360

ccattgtgga ccaaagaaaa acttgaacca atcacacttc aaagtggtca gtctttagta      420

cttccctgca gacccccaat tggattacca ccacctataa tattttggat ggataattcc      480

tttcaaagac ttccacaaag tgagagagtt tctcaaggtt tgaatgggga cctttatttt      540

tccaatgtcc tcccagagga cacccgcgaa gactatatct gttatgctag atttaatcat      600

actcaaacca tacagcagaa gcaacctatt tctgtgaagg tgatttcagc taaatcaagt      660

agagagaggc caccaacatt tttaactcca gaaggcaatg caagtaacaa agaggaatta      720

agaggaaatg tgctttcact ggagtgcatt gcagaaggac tgcctacccc aattatttac      780

tgggcaaagg aagatggaat gctacccaaa aacaggacag tttataagaa ctttgagaaa      840

accttgcaga tcattcatgt ttcagaagca gactctggaa attaccaatg tatagcaaaa      900

aatgcattag gagccatcca ccataccatt tctgttagag ttaaagcggc tccatactgg      960

atcacagccc ctcaaaatct tgtgctgtcc ccaggagagg atgggacctt gatctgcaga     1020

gctaatggca accccaaacc cagaattagc tggttaacaa atggagtccc aatagaaatt     1080

gcccctgatg accccagcag aaaaatagat ggcgatacca ttattttttc aaatgttcaa     1140

gaaagatcaa gtgcagtata tcagtgcaat gcctctaatg aatatggata tttactggca     1200

aacgcatttg taaatgtgct ggctgagcca ccacgaatcc tcacacctgc aaacacactc     1260

taccaggtca ttgcaaacag gcctgcttta ctagactgtg ccttctttgg gtctcctctc     1320

ccaaccatcg agtggtttaa aggagctaaa ggaagtgctc ttcatgaaga tatttatgtt     1380

ttacatgaaa atggaacttt ggaaattcct gtggcccaaa aggacagtac aggaacttat     1440

acgtgtgttg caaggaataa attagggatg gcaaagaatg aagttcactt agaaatcaaa     1500

gatgctacat ggatcgttaa acagcccgaa tatgcagttg tgcaaagagg gagcatggtg     1560

tcctttgaat gcaaagtgaa acatgatcac accttatccc tcactgtcct gtggctgaag     1620

gacaacaggg aactgcccag tgatgaaagg ttcactgttg acaaggatca tctagtggta     1680

gctgatgtca gtgacgatga cagcgggacc tacacgtgtg tggccaacac cactctggac     1740

agcgtctccg ccagcgctgt gcttagcgtt gttgctccta ctccaactcc agctcccgtt     1800

tacgatgtcc caaatcctcc ctttgactta gaactgacag atcaacttga caaaagtgtt     1860

cagctgtcat ggaccccagg cgatgacaac aatagcccca ttacaaaatt catcatcgaa     1920

tatgaagatg caatgcacaa gccagggctg tggcaccacc aaactgaagt ttctggaaca     1980

cagaccacag cccagctgaa gctgtctcct tacgtgaact actccttccg cgtgatggca     2040

gtgaacagca ttgggaagag cttgcccagc gaggcctctg agcagtattt gacgaaagcc     2100

tcagaaccag ataaaaaccc cacagctgtg gaaggactgg gatcagagcc tgataatttg     2160

gtgattacgt ggaagccctt gaatggtttc gaatctaatg ggccaggcct tcagtacaaa     2220

gttagctggc gccagaaaga tggtgatgat gaatggacat ctgtggttgt ggcaaatgta     2280

tccaaatata ttgtctcagg cacgccaacc tttgttccat acctgatcaa agttcaggcc     2340

ctgaatgaca tggggtttgc ccccgagcca gctgtagtca tgggacattc tggagaagac     2400

ctcccaatgg tggctcctgg gaacgtgcgt gtgaatgtgg tgaacagtac cttagccgag     2460

gtgcactggg acccagtacc tctgaaaagc atccgaggac acctacaagg ctatcggatt     2520

tactattgga agacccagag ttcatctaaa agaaacagac gtcacattga gaaaaagatc     2580

ctcaccttcc aaggcagcaa gactcatggc atgttgccgg ggctagagcc ctttagccac     2640

tacacactga atgtccgagt ggtcaatggg aaaggggagg gcccagccag ccctgacaga     2700

gtctttaata ctccagaagg agtccccagt gctccctcgt ctttgaagat tgtgaatcca     2760

acactggact ctctcacttt ggaatgggat ccaccgagcc acccgaatgg cattttgaca     2820

gagtacacct taaagtatca gccaattaac agcacacatg aattaggccc tctggtagat     2880

ttgaaaattc ctgccaacaa gacacggtgg actttaaaaa atttaaattt cagcactcga     2940

tataagtttt atttctatgc acaaacatca gcaggatcag gaagtcaaat tacagaggaa     3000

gcagtaacaa ctgtggatga agctggtatt cttccacctg atgtaggtgc aggcaaagcg     3060

atggcaagcc ggcaggtgga tattgcaact cag                                  3093


<210>  4095
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  4095
tccggcaaga agccggagtc cgcggcgggc agccagagcc cagccttgcc tccccaattg       60

aaagagatga aaagccagga atcggctgca ggttccaaac tagtccttcg gtgtgaaacc      120

agttctgaat actcctctct cagattcaag tggttcaaga atgggaatga attgaatcga      180

aaaaacaaac cacaaaatat caagatacaa aaaaagccag ggaagtcaga acttcgcatt      240

aacaaagcat cactggctga ttctggagag tatatgtgca aagtgatcag caaattagga      300

aatgacagtg cctctgccaa tatcaccatc gtggaatcaa acgagatcat cactggtatg      360

ccagcctcaa ctgaaggagc atatgtgtct tcagagtctc ccattagaat atcagtatcc      420

acagaaggag caaatacttc ttcatctaca tctacatcca ccactgggac aagccatctt      480

gtaaaatgtg cggagaagga gaaaactttc tgtgtgaatg gaggggagtg cttcatggtg      540

aaagaccttt caaacccctc gagatacttg tgcaagtgcc aacctggatt cactggagca      600

agatgtactg agaatgtgcc catgaaagtc caaaaccaag aaaaggcgga ggagctgtac      660

cagaagaga                                                              669


<210>  4096
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  4096
gacaagatct ttgaatatga ctctcctact caccttgacc ctggggggtt aggccaggac       60

cctattattt ctctggacgc aactgctgcc tcagctctgt gggtgtcgtc tgaggcatac      120

acttcacctg tctctagggc tcaatctgaa agtgaggttc aagttacagt gcaaggtgac      180

aaggctgttg tctcctttga accatcagcg gcaccgacac cgaagaatcg tatttttgcc      240

ttttctttct tgccgtccac tgcgccatcc ttcccttcac ccacccggaa ccctgaggtg      300

agaacgccca agtcagcaac tcagccacaa acaacagaaa ctaatctcca aactgctcct      360

aaactttcta catctacatc caccactggg acaagccatc ttgtaaaatg tgcggagaag      420

gagaaaactt tctgtgtgaa tggaggggag tgcttcatgg tgaaagacct ttcaaacccc      480

tcgagatact tgtgcaagtg cccaaatgag tttactggtg atcgctgcca aaactacgta      540

atggccagct tctacagtac gtccactccc tttctgtctc tgcctgaa                   588


<210>  4097
<211>  882
<212>  DNA
<213>  Homo Sapiens

<400>  4097
tgttacagcc cgtcattaaa aagcgttcaa gatcaggcct ataaagcacc tgtggtggtg       60

gaagggaaag ttcagggact ggtcccggca ggtggcagca gtagcaactc caccagggaa      120

ccgcccgcct ctggcagggt cgctcttgtc aaagtgttgg ataagtggcc tctgcgtagc      180

ggcggcttgc agcgtgagca ggtgataagt gtgggctcat gtgtgcccct agaaaggaat      240

caaaggtaca tatttttttt agagccgaca gaacagcccc ttgtgtttaa gaccgctttc      300

gcgcctctgg atacaaacgg caagaatttg aaaaaagaag tcgggaagat cctatgcacc      360

gattgcgcga cgagacctaa acttaagaag atgaagagcc aaaccggcca ggtaggtgaa      420

aagcagtccc tgaaatgtga agctgccgcg ggaaatccgc agccgagcta ccgttggttt      480

aaggacggta aggaattaaa tcgtagtagg gatattagga taaaatacgg aaatggcaga      540

aaaaacagcc gtttgcagtt caataaggtg aaggtggagg acgcgggcga gtacgtgtgc      600

gaggcagaaa atatcttagg caaggatact gtcaggggta ggttgtacgt gaatagtgtt      660

tccactactc tgtcatcatg gtccggccat gctcgtaaat gcaacgagac agccaagagc      720

tattgtgtga atggaggagt atgttactat atcgaaggga taaaccaatt gtcatgtaaa      780

tgccctaatg gttttttcgg acagcgttgt ttagaaaaac tgccgttgag actttacatg      840

ccggacccca aacagaaggc ggaggaatta taccaaaaaa gg                         882


<210>  4098
<211>  1077
<212>  DNA
<213>  Homo Sapiens

<400>  4098
atgagtgaag gggcggccgc tgcctcgcca cctggtgccg cttcggcagc cgccgcctcg       60

gccgaggagg gcaccgcggc ggctgcggcg gcggcagcgg cgggcggggg cccggacggc      120

ggcggcgaag gggcggccga gcccccccgg gagttacgct gtagcgactg catcgtgtgg      180

aaccggcagc agacgtggct gtgcgtggta cctctgttca tcggcttcat cggcctgggg      240

ctcagcctca tgcttctcaa atggatcgtg gtgggctccg tcaaggagta cgtgcccacc      300

gacctagtgg actccaaggg gatgggccag gaccccttct tcctctccaa gcccagctct      360

ttccccaagg ccatggagac caccaccact accacttcca ccacgtcccc cgccaccccc      420

tccgccgggg gtgccgcctc ctccaggacg cccaaccgga ttagcactcg cctgaccacc      480

atcacgcggg cgcccactcg cttccccggg caccgggtgc ccatccgggc cagcccgcgc      540

tccaccacag cacggaacac tgcggcccct gcgacggtcc cgtccaccac ggccccgttc      600

ttcagtagca gcacgctggg ctcccgaccc ccggtgccag gaactccaag tacccaggca      660

atgccctcct ggcctactgc ggcatacgct acctcctcct accttcacga ttctactccc      720

tcctggaccc tgtctccctt tcaggatgct gcctcctctt cttcctcttc ttcctcctcc      780

gctaccacca ccacaccaga aactagcacc agccccaaat ttcatacgac gacatattcc      840

acagagcgat ccgagcactt caaaccctgc cgagacaagg accttgcata ctgtctcaat      900

gatggcgagt gctttgtgat cgaaaccctg accggatccc ataaacactg tcggtgcaaa      960

gaaggctacc aaggagtccg ttgtgatcaa tttctgccga aaactgattc catcttatcg     1020

gatccaaacc acttggggat tgaattcatg gagagtgaag aagtttatca aaggcag        1077


<210>  4099
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  4099
atgccaacag atcacgaaga gccctgtggt cccagtcaca agtcgttttg cctgaatggg       60

gggctttgtt atgtgatacc tactattccc agcccatttt gtaggtgcgt tgaaaactat      120

acaggagctc gttgtgaaga ggtttttctc ccaggctcca gcatccaaac taaaagtaac      180

ctg                                                                    183


<210>  4100
<211>  2505
<212>  DNA
<213>  Homo Sapiens

<400>  4100
tttcgcaacg ataaatgtgg cgatactata aaaattgaaa gccccgggta ccttacatct       60

cctggttatc ctcattctta tcacccaagt gaaaaatgcg aatggctgat tcaggctccg      120

gacccatacc agagaattat gatcaacttc aaccctcact tcgatttgga ggacagagac      180

tgcaagtatg actacgtgga agtcttcgat ggagaaaatg aaaatggaca ttttagggga      240

aagttctgtg gaaagatagc ccctcctcct gttgtgtctt cagggccatt tctttttatc      300

aaatttgtct ctgactacga aacacatggt gcaggatttt ccatacgtta tgaaattttc      360

aagagaggtc ctgaatgttc ccagaactac acaacaccta gtggagtgat aaagtccccc      420

ggattccctg aaaaatatcc caacagcctt gaatgcactt atattgtctt tgcaccaaag      480

atgtcagaga ttatcctgga atttgaaagc tttgacctgg agcctgactc aaatcctcca      540

ggggggatgt tctgtcgcta cgaccggcta gaaatctggg atggattccc tggtgttggc      600

cctcacattg ggcgttactg tggacagaaa acaccaggtc gaatccgatc ctcatcgggc      660

attctctcca tggtttttta caccgacagc gcgatagcaa aagaaggttt ctcagcaaac      720

tacagtgttt tgcagagcag tgtctcagaa gatttcaaat gtatggaagc tctgggcatg      780

gaatcaggag aaattcattc tgaccagatc acagcttctt cccagtatag caccaactgg      840

tctgcagagc gctcccgcct gaactaccct gagaatgggt ggactcccgg agaggattcc      900

taccgagagt ggatacaggt agacttgggc cttctgcgct ttgtcacggc tgtcgggaca      960

cagggcgcca tttcaaaaga aaccaagaag aaatattatg tcaagactta caagatcgac     1020

gttagctcca acggggaaga ctggatcacc ataaaagaag gaaacaaacc tgttctcttt     1080

cagggaaaca ccaaccccac agatgttgtg gttgcagtat tccccaaacc actgataact     1140

cgatttgtcc gaatcaagcc tgcaacttgg gaaactggca tatctatgag atttgaagta     1200

tacggttgca agataacaga ttatccttgc tctggaatgt tgggtatggt gtctggactt     1260

atttctgact cccagatcac atcatccaac caaggggaca gaaactggat gcctgaaaac     1320

atccgcctgg taaccagtcg ctctggctgg gcacttccac ccgcacctca ttcctacatc     1380

aatgagtggc tccaaataga cctgggggag gagaagatcg tgaggggcat catcattcag     1440

ggtgggaagc accgagagaa caaggtgttc atgaggaagt tcaagatcgg gtacagcaac     1500

aacggctcgg actggaagat gatcatggat gacagcaaac gcaaggcgaa gtcttttgag     1560

ggcaacaaca actatgatac acctgagctg cggacttttc cagctctctc cacgcgattc     1620

atcaggatct accccgagag agccactcat ggcggactgg ggctcagaat ggagctgctg     1680

ggctgtgaag tggaagcccc tacagctgga ccgaccactc ccaacgggaa cttggtggat     1740

gaatgtgatg acgaccaggc caactgccac agtggaacag gtgatgactt ccagctcaca     1800

ggcggcacca ctgtgccggc cacagaaaag cccacggtca tagacagcac catacaatca     1860

gagtttccaa catatggttt taactgtgaa tttggctggg gctctcacaa gaccttctgc     1920

cactgggaac atgacaatca cgtgcagctc aagtggagtg tgttgaccag caagacggga     1980

cccattcagg atcacacagg agatggcaac ttcatctatt cccaagctga cgaaaatcag     2040

aagggcaaag tggctcgcct ggtgagccct gtggtttatt cccagaactc tgcccactgc     2100

atgaccttct ggtatcacat gtctgggtcc cacgtcggca cactcagggt caaactgcgc     2160

taccagaagc cagaggagta cgatcagctg gtctggatgg ccattggaca ccaaggtgac     2220

cactggaagg aagggcgtgt cttgctccac aagtctctga aactttatca ggtgattttc     2280

gagggcgaaa tcggaaaagg aaaccttggt gggattgctg tggatgacat tagtattaat     2340

aaccacattt cacaagaaga ttgtgcaaaa ccagcagacc tggataaaaa gaacccagaa     2400

attaaaattg atgaaacagg gagcacgcca ggatacgaag gtgaaggaga aggtgacaag     2460

aacatctcca ggaagccagg caatgtgttg aagaccttag acccc                     2505


<210>  4101
<211>  2517
<212>  DNA
<213>  Homo Sapiens

<400>  4101
agaggccaac cagacccacc gtgcggaggt cgtttgaatt ccaaagatgc tggctatatc       60

acctctcccg gttaccccca ggactacccc tcccaccaga actgcgagtg gattgtttac      120

gcccccgaac ccaaccagaa gattgtcctc aacttcaacc ctcactttga aatcgagaag      180

cacgactgca agtatgactt tatcgagatt cgggatgggg acagtgaatc cgcagacctc      240

ctgggcaaac actgtgggaa catcgccccg cccaccatca tctcctcggg ctccatgctc      300

tacatcaagt tcacctccga ctacgcccgg cagggggcag gcttctctct gcgctacgag      360

atcttcaaga caggctctga agattgctca aaaaacttca caagccccaa cgggaccatc      420

gaatctcctg ggtttcctga gaagtatcca cacaacttgg actgcacctt taccatcctg      480

gccaaaccca agatggagat catcctgcag ttcctgatct ttgacctgga gcatgaccct      540

ttgcaggtgg gagaggggga ctgcaagtac gattggctgg acatctggga tggcattcca      600

catgttggcc ccctgattgg caagtactgt gggaccaaaa caccctctga acttcgttca      660

tcgacgggga tcctctccct gacctttcac acggacatgg cggtggccaa ggatggcttc      720

tctgcgcgtt actacctggt ccaccaagag ccactagaga actttcagtg caatgttcct      780

ctgggcatgg agtctggccg gattgctaat gaacagatca gtgcctcatc tacctactct      840

gatgggaggt ggacccctca acaaagccgg ctccatggtg atgacaatgg ctggaccccc      900

aacttggatt ccaacaagga gtatctccag gtggacctgc gctttttaac catgctcacg      960

gccatcgcaa cacagggagc gatttccagg gaaacacaga atggctacta tgtcaaatcc     1020

tacaagctgg aagtcagcac taatggagag gactggatgg tgtaccggca tggcaaaaac     1080

cacaaggtat ttcaagccaa caacgatgca actgaggtgg ttctgaacaa gctccacgct     1140

ccactgctga caaggtttgt tagaatccgc cctcagacct ggcactcagg tatcgccctc     1200

cggctggagc tcttcggctg ccgggtcaca gatgctccct gctccaacat gctggggatg     1260

ctctcaggcc tcattgcaga ctcccagatc tccgcctctt ccacccagga atacctctgg     1320

agccccagtg cagcccgcct ggtcagcagc cgctcgggct ggttccctcg aatccctcag     1380

gcccagcccg gtgaggagtg gcttcaggta gatctgggaa cacccaagac agtgaaaggt     1440

gtcatcatcc agggagcccg cggaggagac agtatcactg ctgtggaagc cagagcattt     1500

gtgcgcaagt tcaaagtctc ctacagccta aacggcaagg actgggaata cattcaggac     1560

cccaggaccc agcagccaaa gctgttcgaa gggaacatgc actatgacac ccctgacatc     1620

cgaaggtttg accccattcc ggcacagtat gtgcgggtat acccggagag gtggtcgccg     1680

gcggggattg ggatgcggct ggaggtgctg ggctgtgact ggacagactc caagcccacg     1740

gtagagacgc tgggacccac tgtgaagagc gaagagacaa ccacccccta ccccaccgaa     1800

gaggaggcca cagagtgtgg ggagaactgc agctttgagg atgacaaaga tttgcagctc     1860

ccttcgggat tcaattgcaa cttcgatttc ctcgaggagc cctgtggttg gatgtatgac     1920

catgccaagt ggctccggac cacctgggcc agcagctcca gcccaaacga ccggacgttt     1980

ccagatgaca ggaatttctt gcggctgcag agtgacagcc agagagaggg ccagtatgcc     2040

cggctcatca gcccccctgt ccacctgccc cgaagcccgg tgtgcatgga gttccagtac     2100

caggccacgg gcggccgcgg ggtggcgctg caggtggtgc gggaagccag ccaggagagc     2160

aagttgctgt gggtcatccg tgaggaccag ggcggcgagt ggaagcacgg gcggatcatc     2220

ctgcccagct acgacatgga gtaccagatt gtgttcgagg gagtgatagg gaaaggacgt     2280

tccggagaga ttgccattga tgacattcgg ataagcactg atgtcccact ggagaactgc     2340

atggaaccca tctcggcttt tgcagtggac atcccagaaa tacatgagag agaaggatat     2400

gaagatgaaa ttgatgatga atacgaggtg gactggagca attcttcttc tgcaacctca     2460

gggtctggcg ccccctcgac cgacaaagaa aagagctggc tgtacaccct ggatccc        2517


<210>  4102
<211>  1896
<212>  DNA
<213>  Homo Sapiens

<400>  4102
tggaggaaca gaagcggaac agccacagca gcctcccaag gagtctgcaa gttggtgggt       60

ggagccgctg actgccgagg gcagagcctc gcttcggtgc ccagcagcct cccgccccac      120

gcccggatgc tcaccctgga tgccaaccct ctcaagaccc tgtggaatca ctccctccag      180

ccttaccctc tcctggagag cctcagcctg cacagctgcc acctggagcg catcagccgc      240

ggcgccttcc aggagcaagg tcacctgcgc agcctggtac tgggggacaa ctgcctctca      300

gagaactacg aagagacggc agccgccctc cacgccctgc cgggcctgcg gaggctggac      360

ttgtcaggaa acgccctgac ggaggacatg gcagcgctca tgctccagaa cctctcctcg      420

ctgcggtccg tgtccctggc ggggaacacc atcatgcggc tggacgactc cgtcttcgag      480

ggcctggagc gtctccggga gctggatctg cagaggaact acatcttcga gatcgagggc      540

ggcgctttcg acggcctggc tgagctgagg cacctcaacc tggccttcaa caacctcccc      600

tgcatcgtgg acttcgggct cacgcggctg cgggtcctca acgtcagcta caacgtcctg      660

gagtggttcc tcgcgaccgg gggagaggct gccttcgagc tggagacgct ggacctgtct      720

cacaaccagc tgctgttctt cccgctgctg ccccagtaca gcaagttgcg gaccctcctg      780

ctgcgcgaca acaacatggg cttctaccgg gacctgtaca acacctcgtc gccgagggag      840

atggtggccc agttcctcct cgtggacggc aacgtgacca acatcaccac cgtcagcctc      900

tgggaagaat tctcctccag cgacctcgca gatctccgct tcctggacat gagccagaac      960

cagttccagt acctgccaga cggcttcctg aggaaaatgc cttccctctc ccacctgaac     1020

ctccaccaga attgcctgat gacgcttcac attcgggagc acgagccccc cggagcgctc     1080

accgagctgg acctgagcca caaccagctg tcggagctgc acctggctcc ggggctggcc     1140

agctgcctgg gcagcctgcg cttgttcaac ctgagctcca accagctcct gggcgtcccc     1200

cctggcctct tcgccaatgc taggaacatc actacacttg acatgagcca caatcagatc     1260

tcactttgtc ccctgccagc tgcctcggac cgggtgggcc cccctagctg tgtggatttc     1320

aggaatatgg catctttaag gagcctgtct ctggagggct gtggcctggg ggcattgcca     1380

gactgcccat tccaagggac ctccctgacc tacttagacc tctcaagcaa ctggggggtt     1440

ctgaatggga gcctcgcccc actccaggat gttgccccca tgttacaggt cctgtctctc     1500

aggaacatgg gcctccactc cagctttatg gcgttggact tctctgggtt tgggaatctc     1560

agggacttag atctgtcggg gaattgcttg accaccttcc caaggtttgg gggcagcctg     1620

gccctggaga ccctggatct ccgtagaaac tcgctcacag cccttcccca gaaggctgtg     1680

tctgagcagc tctcgagagg tctgcggacc atctacctca gtcagaatcc atatgactgc     1740

tgtggggtgg atggctgggg ggccctgcag catgggcaga cggtggccga ctgggccatg     1800

gtcacctgca acctctcctc caagatcatc cgcgtgacgg agctgcccgg aggtgtgcct     1860

cgggactgca agtgggagcg gctggacctg ggcctg                               1896


<210>  4103
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  4103
ctggagtttc cgggcgccga gggccaatgg acgcgcttcc ccaagtggaa cgcctgctgc       60

gagagcgaga tgagcttcca gctcaagact cgcagcgccc gcggcctcgt gctctacttc      120

gacgacgagg gcttctgcga cttcctggag ctgattctga cgcgcggcgg ccgcctgcag      180

ctcagcttct ccgtcttctg cgctgagcct gcgacgctcc tggccgacac gccggttaac      240

gacggcgcct ggcacagcgt gcgcatccgc cgccagttcc gcaacaccac gctcttcatc      300

gaccaggtgg aggccaagtg ggtggaggtc aagtccaagc gcagggacat gacggtgttc      360

agcggccttt tcgtcggggg gctgcccccg gaactgcgcg ccgcggcgct caagctcacc      420

ctggcctcgg tgagggagcg ggagcccttc aaggggtgga ttcgtgacgt gggggtcaac      480

tcctcgcagg tcctgcccgt ggacagcggc gaggtgaagc tggacgatga gccgcccaac      540

agcggcgggg gaagcccgtg cgaggcgggc gaggagggcg agggcggggt gtgcctcaac      600

ggaggtgtgt gctccgtggt ggacgaccag gccgtgtgcg actgctcgcg aaccggcttc      660

cgcggcaagg actgcagcca agaagacaac aatgtggaag gtctggcgca cctgatgatg      720

ggcgaccaag gtaaaagtaa agat                                             744


<210>  4104
<211>  1047
<212>  DNA
<213>  Homo Sapiens

<400>  4104
tcttctaatg tagcttcctc ctcctccacc tcttcctcgc cggggtctca ctctcagcac       60

gagcaccatt tccatggcag caagcatcac tcagtgccta tttctatcta tcgttcccct      120

gtttcccttc gaggaggaca cgctggcgct acgtacatct ttgggaaaag tggtgggctt      180

atcctctaca cctggccagc caatgacagg cccagcacgc ggtctgaccg ccttgccgtg      240

ggcttcagca ccactgtgaa ggatggcatc ttggtccgca tcgacagtgc tccaggactt      300

ggtgacttcc tccagcttca catagaacag gggaaaattg gagttgtctt caacattggc      360

acagttgaca tctccatcaa agaggagaga acccctgtaa atgacggcaa ataccatgtg      420

gtacgcttca ccaggaacgg cggcaacgcc accctgcagg tggacaactg gccagtgaat      480

gaacattatc ctacaggcaa cactgataat gaacgcttcc aaatggtaaa acagaaaatc      540

cccttcaaat ataatcggcc tgtagaggag tggctgcagg aaaaaggccg gcagttaacc      600

atcttcaaca ctcaggcgca aatagccatt ggtggaaagg acaaaggacg cctcttccaa      660

ggccaactct ctgggctcta ttatgatggt ttgaaagtac tgaacatggc ggctgagaac      720

aaccccaata ttaaaatcaa tggaagtgtt cggctggttg gagaagtccc atcaattttg      780

ggaacaacac agacgacctc catgccacca gaaatgtcta ctactgtcat ggaaaccact      840

actacaatgg cgactaccac aacccgtaag aatcgctcta cagccagcat tcagccaaca      900

tcagatgatc ttgtttcatc tgctgaatgt tcaagtgatg atgaagactt tgttgaatgt      960

gagccgagta cagcaaaccc cacggagccg ggaatcagac gggttccggg ggcctcagag     1020

gtgatccggg agtcgagcag cacaaca                                         1047


<210>  4105
<211>  1569
<212>  DNA
<213>  Homo Sapiens

<400>  4105
tgggagctta cgattttgca caccaacgac gtgcacagcc ggctggagca gaccagcgag       60

gactccagca agtgcgtcaa cgccagccgc tgcatgggtg gcgtggctcg gctcttcacc      120

aaggttcagc agatccgccg cgccgaaccc aacgtgctgc tgctggacgc cggcgaccag      180

taccagggca ctatctggtt caccgtgtac aagggcgccg aggtggcgca cttcatgaac      240

gccctgcgct acgatgccat ggcactggga aatcatgaat ttgataatgg tgtggaagga      300

ctgatcgagc cactcctcaa agaggccaaa tttccaattc tgagtgcaaa cattaaagca      360

aaggggccac tagcatctca aatatcagga ctttatttgc catataaagt tcttcctgtt      420

ggtgatgaag ttgtgggaat cgttggatac acttccaaag aaaccccttt tctctcaaat      480

ccagggacaa atttagtgtt tgaagatgaa atcactgcat tacaacctga agtagataag      540

ttaaaaactc taaatgtgaa caaaattatt gcactgggac attcgggttt tgaaatggat      600

aaactcatcg ctcagaaagt gaggggtgtg gacgtcgtgg tgggaggaca ctccaacaca      660

tttctttaca caggcaatcc accttccaaa gaggtgcctg ctgggaagta cccattcata      720

gtcacttctg atgatgggcg gaaggttcct gtagtccagg cctatgcttt tggcaaatac      780

ctaggctatc tgaagatcga gtttgatgaa agaggaaacg tcatctcttc ccatggaaat      840

cccattcttc taaacagcag cattcctgaa gatccaagca taaaagcaga cattaacaaa      900

tggaggataa aattggataa ttattctacc caggaattag ggaaaacaat tgtctatctg      960

gatggctcct ctcaatcatg ccgctttaga gaatgcaaca tgggcaacct gatttgtgat     1020

gcaatgatta acaacaacct gagacacgcg gatgaaacgt tctggaacca cgtatccatg     1080

tgcattttaa atggaggtgg tatccggtcg cccattgatg aacgcaacaa tggcacaatt     1140

acctgggaga acctggctgc tgtattgccc tttggaggca catttgacct agtccagtta     1200

aaaggttcca ccctgaagaa ggcctttgag catagcgtgc accgctacgg ccagtccact     1260

ggagagttcc tgcaggtggg cggaatccat gtggtgtatg atctttcccg aaaacctgga     1320

gacagagtag tcaaattaga tgttctttgc accaagtgtc gagtgcccag ttatgaccct     1380

ctcaaaatgg acgaggtata taaggtgatc ctcccaaact tcctggccaa tggtggagat     1440

gggttccaga tgataaaaga tgaattatta agacatgact ctggtgacca agatatcaac     1500

gtggtttcta catatatctc caaaatgaaa gtaatttatc cagcagttga aggtcggatc     1560

aagttttcc                                                             1569


<210>  4106
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4106
tacgcggagc ataagagtca ccgaggggag tactcggtat gtgacagtga gagtctgtgg       60

gtgaccgaca agtcatcggc catcgacatt cggggacacc aggtcacggt gctgggggag      120

atcaaaacgg gcaactctcc cgtcaaacaa tatttttatg aaacgcgatg taaggaagcc      180

aggccggtca aaaacggttg caggggtatt gatgataaac actggaactc tcagtgcaaa      240

acatcccaaa cctacgtccg agcactgact tcagagaaca ataaactcgt gggctggcgg      300

tggatacgga tagacacgtc ctgtgtgtgt gccttgtcga gaaaaatcgg aagaaca         357


<210>  4107
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  4107
ggggtgagcg aaactgcacc agcgagtcgt cggggtgagc tggctgtgtg cgatgcagtc       60

agtggctggg tgacagaccg ccggaccgct gtggacttgc gtgggcgcga ggtggaggtg      120

ttgggcgagg tgcctgcagc tggcggcagt cccctccgcc agtacttctt tgaaacccgc      180

tgcaaggctg ataacgctga ggaaggtggc ccgggggcag gtggaggggg ctgccgggga      240

gtggacagga ggcactgggt atctgagtgc aaggccaagc agtcctatgt gcgggcattg      300

accgctgatg cccagggccg tgtgggctgg cgatggattc gaattgacac tgcctgcgtc      360

tgcacactcc tcagccggac tggccgggcc                                       390


<210>  4108
<211>  849
<212>  DNA
<213>  Homo Sapiens

<400>  4108
ggagatgcca ccttccccaa agctatggac aacgtgacgg tccggcaggg ggagagcgcc       60

accctcaggt gcactattga caaccgggtc acccgggtgg cctggctaaa ccgcagcacc      120

atcctctatg ctgggaatga caagtggtgc ctggatcctc gcgtggtcct tctgagcaac      180

acccaaacgc agtacagcat cgagatccag aacgtggatg tgtatgacga gggcccttac      240

acctgctcgg tgcagacaga caaccaccca aagacctcta gggtccacct cattgtgcaa      300

gtatctccca aaattgtaga gatttcttca gatatctcca ttaatgaagg gaacaatatt      360

agcctcacct gcatagcaac tggtagacca gagcctacgg ttacttggag acacatctct      420

cccaaagcgg ttggctttgt gagtgaagac gaatacttgg aaattcaggg catcacccgg      480

gagcagtcag gggactacga gtgcagtgcc tccaatgacg tggccgcgcc cgtggtacgg      540

agagtaaagg tcaccgtgaa ctatccacca tacatttcag aagccaaggg tacaggtgtc      600

cccgtgggac aaaaggggac actgcagtgt gaagcctcag cagtcccctc agcagaattc      660

cagtggtaca aggatgacaa aagactgatt gaaggaaaga aaggggtgaa agtggaaaac      720

agacctttcc tctcaaaact catcttcttc aatgtctctg aacatgacta tgggaactac      780

acttgcgtgg cctccaacaa gctgggccac accaatgcca gcatcatgct atttggtgag      840

actgtgctc                                                              849


<210>  4109
<211>  1740
<212>  DNA
<213>  Homo Sapiens

<400>  4109
ggaccaggtc tttcaatgtt cgctgggcaa gcggctcagc ccgatccatg tagtgatgaa       60

aacggacatc caagaaggtg catacccgac tttgtcaacg ccgcttttgg caaagacgtg      120

agagtctcat ccacgtgtgg aaggccaccc gccagatact gcgtcgttag cgaaaggggc      180

gaggaaaggc tgcgttcatg tcacctatgc aacgcatctg atccgaaaaa agcccatcca      240

ccagcctttc ttacagatct gaataatccg cataatctaa cgtgttggca gtcagagaac      300

tatctacagt ttccacataa tgtcacgttg actttaagcc taggcaaaaa gttcgaggta      360

acatacgtgt ccctacaatt ctgtagcccc aggcccgagt ccatggccat ctacaagtct      420

atggactatg ggcgtacttg ggttcctttc caattttact ctactcaatg cagaaaaatg      480

tataataggc ctcacagggc acctataacg aagcagaatg agcaggaggc cgtgtgcaca      540

gactcccaca cggatatgcg tccgttaagt ggtggactta ttgccttcag cacgttggat      600

gggcgtccca gtgcacacga ttttgataat tccccggtac ttcaggactg ggtaactgcc      660

accgatattc gtgtagcttt tagcagatta cacacgttcg gagatgagaa cgaagacgac      720

tctgagctgg ctagagatag ctatttttac gctgtcagtg accttcaggt gggggggaga      780

tgtaaatgta acggacacgc tgctagatgc gtgagggatc gtgatgactc cctggtatgc      840

gattgtcgtc ataataccgc tggtcccgag tgtgatagat gtaaaccatt ccattacgac      900

cgtccctggc aacgtgcgac agcgagagag gctaatgaat gtgttgcatg taactgcaac      960

cttcatgcca gacgttgcag attcaacatg gaactatata aactatccgg tagaaagtct     1020

ggtggtgtgt gcctgaattg tcgtcataac accgcgggac gtcactgcca ttactgcaaa     1080

gagggatatt acagggacat ggggaagccc attactcaca ggaaggcctg taaggcatgc     1140

gactgtcacc cggtaggcgc tgctggaaag acatgtaacc agacaacggg ccaatgtcct     1200

tgtaaagacg gagtcaccgg gataacatgt aacagatgtg cgaaaggata ccagcaaagc     1260

aggagtccca ttgcaccgtg tattaaaatc ccggtggccc cgcccacaac cgcagcaagc     1320

tccgtagagg agccggaaga ttgcgattct tattgtaagg caagcaaggg aaagttgaag     1380

attaacatga agaagtactg caaaaaagac tacgctgttc aaatacacat cctgaaagct     1440

gacaaagcgg gtgactggtg gaaatttact gttaacatta tcagtgtata taaacaaggg     1500

accagtcgta taaggcgtgg tgaccagtct ctgtggatta gatctcgtga catagcgtgc     1560

aagtgtccta agatcaagcc gttaaagaag tacttactac taggaaacgc cgaggacagt     1620

cccgaccaaa gcggtatagt agctgacaag agtagtctag taattcaatg gcgtgatacc     1680

tgggcccgta gattaaggaa attccagcaa agagaaaaga aaggtaaatg taaaaaggca     1740


<210>  4110
<211>  1659
<212>  DNA
<213>  Homo Sapiens

<400>  4110
gacccatgcc atgatgaggg cggtgcgccg aggggatgtg tgcctggtct agtaaatgcc       60

gcgctaggaa gagaggtttt ggcgagctcc acctgtggga ggcccgcaac acgtgcgtgc      120

gatgcctcag acccccgtcg tgcccatagt cctgctttgc tgacatcacc gggaggcacg      180

gccagtcctc tatgttggag gagtgaatct ctgccgcgtg cccccttaaa tgtaaccctt      240

acagtccctt tggggaaagc gtttgaatta gtctttgtta gcttgaggtt ttgctcagct      300

cctccagctt ccgtggcctt acttaaatct caagatcacg gtcgttcttg ggctcccttg      360

ggctttttct cttcccactg cgacctagat tatggcagac taccagctcc tgcgaatgga      420

ccggcagggc caggtccaga agcgttgtgt tttccagctc cacttgcgca gccagacggt      480

agcggcttgt tggcgttctc tatgcaggac agttccccgc caggtttaga cctagattca      540

tccccggtac tacaagattg ggttacggca acagatgtta gagtcgtctt aaccagacct      600

tctactgcgg gcgatcccag agacatggaa gctgttgtgc cctactctta cgccgcgacg      660

gatttgcaag taggtggcag gtgcaagtgc aacggtcatg cctcaagatg cttgttagac      720

acgcaagggc atttgatttg tgattgcaga cacggcacgg aaggtccaga ctgtggacgt      780

tgtaagccat tctattgtga cagaccttgg caaagggcaa cagcgcgtga aagccacgcg      840

tgtctggctt gcagctgtaa tgggcacgct aggaggtgca ggtttaatat ggaactgtac      900

aggctgtctg gtagaagatc aggcggagtt tgcctgaact gtaggcataa taccgccggt      960

agacactgcc attattgccg tgagggtttc taccgtgacc cgggcagggc gctgtccgac     1020

agaagggcct gtagagcatg cgactgtcac ccggtaggcg cggcgggaaa aacgtgtaat     1080

caaaccacag gccagtgtcc atgcaaggac ggcgtaactg ggttgacatg taatagatgc     1140

gcgccaggat ttcagcagtc tagatctcca gttgcgccct gtgtcaaaac tccgatcccg     1200

ggaccgacgg aagattcaag tccggtacaa ccacaggact gcgattcaca ttgtaagccg     1260

gctagagggt cctaccgtat ctctctaaag aaattttgca aaaaagacta tgctgtgcaa     1320

gttgctgtcg gcgctagagg tgaagccaga ggagcgtgga cgcgttttcc agtcgcagta     1380

ctagccgtct ttagaagtgg agaggaaagg gcgcgtaggg gcagtagcgc cttgtgggtg     1440

cccgccggag atgcagcatg tgggtgtcca cgtctgctgc cagggaggcg ttatctacta     1500

cttggagggg gtccaggagc agcagcaggg ggcgctggtg gacgtgggcc aggtctaatc     1560

gctgccagag gtagtctggt tttaccgtgg agagatgcat ggactagacg tctaagaaga     1620

ttgcaaagga gggaacgtcg tggaagatgt tccgcagcg                            1659


<210>  4111
<211>  1830
<212>  DNA
<213>  Homo Sapiens

<400>  4111
ggactgagtg gagtagctgg agtgagttcc cgctgtgaaa aagcctgcaa ccctcggatg       60

ggaaatttgg ctttggggcg aaaactctgg gcagacacca cctgcggtca gaatgctacc      120

gaactgtact gcttctacag tgagaacacg gatctgactt gtcggcagcc caaatgtgac      180

aagtgcaatg ctgcctatcc tcacctggct cacctgccat ctgccatggc agactcatcc      240

ttccggtttc ctcgcacatg gtggcagtct gcggaggatg tgcacagaga aaagatccag      300

ttagacctgg aagctgaatt ctacttcact cacctaattg tgatgttcaa gtcccccagg      360

ccggctgcca tggtgctgga ccgctcccag gactttggga aaacatggaa gccttataag      420

tactttgcga ctaactgctc cgctacattt ggcctggaag atgatgttgt caagaagggc      480

gctatttgta cttctaaata ctccagtcct tttccatgca ctggaggaga ggttattttc      540

aaagctttgt caccaccata cgatacagag aacccttaca gtgccaaagt tcaggagcag      600

ctgaagatca ccaaccttcg cgtgcagctg ctgaaacgac agtcttgtcc ctgtcagaga      660

aatgacctga acgaagagcc tcaacatttt acacactatg caatctatga tttcattgtc      720

aagggcagct gcttctgcaa tggccacgct gatcaatgca tacctgttca tggcttcaga      780

cctgtcaagg ccccaggaac attccacatg gtccatggga agtgtatgtg taagcacaac      840

acagcaggca gccactgcca gcactgtgcc ccgttataca atgaccggcc atgggaggca      900

gctgatggca aaacgggggc tcccaacgag tgcagaacct gcaagtgtaa tgggcatgct      960

gatacctgtc acttcgacgt taatgtgtgg gaggcatcag ggaatcgtag tggtggtgtc     1020

tgtgatgact gtcagcacaa cacagaagga cagtattgcc agaggtgcaa gccaggcttc     1080

tatcgtgacc tgcggagacc cttctcagct ccagatgctt gcaaaccgtg ttcctgccat     1140

ccagtaggat cagctgtcct tcctgccaac tcagtgacct tctgcgaccc cagcaatggt     1200

gactgccctt gcaagcctgg ggtggcaggg cgacgttgtg acaggtgcat ggtgggatac     1260

tggggcttcg gagactatgg ctgtcgacca tgtgactgtg cggggagctg tgaccctatc     1320

accggagact gcatcagcag ccacacagac atagactggt atcatgaagt tcctgacttc     1380

cgtcccgtgc acaataagag cgaaccagcc tgggagtggg aggatgcgca ggggttttct     1440

gcacttctac actcaggtaa atgcgaatgt aaggaacaga cattaggaaa tgccaaggca     1500

ttctgtggaa tgaaatattc atatgtgcta aaaataaaga ttttatcagc tcatgataaa     1560

ggtactcatg ttgaggtcaa tgtgaagatt aaaaaggtct taaaatctac caaactgaag     1620

attttccgag gaaagcgaac attatatcca gaatcatgga cggacagagg atgcacttgt     1680

ccaatcctca atcctggttt ggaatacctt gtagcaggac atgaggatat aagaacaggc     1740

aaactaattg tgaatatgaa aagctttgtc cagcactgga aaccttctct tggaagaaaa     1800

gtcatggata ttttaaaaag agagtgcaag                                      1830


<210>  4112
<211>  1419
<212>  DNA
<213>  Homo Sapiens

<400>  4112
gacccatgct acgatccaca gggccgcccc caattctgcc tcccgccagt gacacagctg       60

gctgccgtgg cggcctcctg ccctcaggcc tgtgccctgt ccccaggaaa ccaccttggc      120

gccagggaaa cctgcaatgg cagcctgact ttggccctgg gtggcccctt cctcctgaca      180

tctgtcagct tgcgcttctg taccccagga cccccagccc tcatcctgtc tgctgcctgg      240

gcctcagggg gtccctggag gctgctgtgg cacaggcccg cctggcctgg ggccttaggg      300

ggccctgaaa gggtgacctt ccactccaca ccaggtccta aggccactgt ggcggccagc      360

cacctccgtg tggagtttgg gggccaggcc gggctagcgg cagctgggct gagaggccgc      420

tgccagtgtc atggccacgc tgcccgctgt gccgcccgtg cccggccccc ccgctgccac      480

tgccgccacc ataccactgg cccggggtgc gagagctgcc gcccgtccca tcgagactgg      540

ccctggcggc ctgccacgcc ccggcacccc cacccttgcc taccctgctc ctgcaaccag      600

cacgcccgac gctgccggtt caactctgag ctgttcagac tgtcgggcgg ccggagtggg      660

ggtgtttgtg agcggtgccg ccaccacaca gctgggcggc actgccacta ctgccaacct      720

gggttctgga gggaccctag ccagcctatc ttcagccgca gggcctgcag agcctgccag      780

tgccacccta ttggggcaac aggaggaacc tgcaaccaga ccagtgggca gtgcacctgc      840

aagttagggg tcacaggcct gacctgcaac cgctgtggcc ctggctacca gcagagccgc      900

tcccccagga tgccctgcca gcgaattcca gaggcaacaa ccacccttgc cactactcct      960

ggtgcttata gctctgaccc tcagtgtcaa aactactgca atatgtcgga caccagggta     1020

cacatgagcc ttcggaggta ctgccagcag gaccatgttc tccgcgcgca ggtgctagcg     1080

tccgaggcgg cgggcccggc atggcagcgg ctggccgtgc gcgtgctggc cgtttacaag     1140

cagcgggcgc agcccgtgcg acgcggcgac caggacgcct gggtgccccg cgccgacctg     1200

acctgcggct gcctgcgcct gcagccaggc accgactacc tgctgctggg cagcgccgtg     1260

ggcgaccccg accccacgcg cctcatcctc gaccgccacg gcctcgcgct gccatggagg     1320

ccgcgctggg cccggcccct gaagcggctg cagcaggagg agcgcgccgg aggctgccgc     1380

ggcgtgcggg cacccacacc cagccccagg ccggagcac                            1419


<210>  4113
<211>  1143
<212>  DNA
<213>  Homo Sapiens

<400>  4113
cattatgatt tgtgtaagac tcagatttac acggaagaag ggaaagtttg ggattacatg       60

gcctgccagc cggaatccac ggacatgaca aaatatctga aagtgaaact cgatcctccg      120

gatattacct gtggagaccc tcctgagacg ttctgtgcaa tgggcaatcc ctacatgtgc      180

aataatgagt gtgatgcgag tacccctgag ctggcacacc cccctgagct gatgtttgat      240

tttgaaggaa gacatccctc cacattttgg cagtctgcca cttggaagga gtatcccaag      300

cctctccagg ttaacatcac tctgtcttgg agcaaaacca ttgagctaac agacaacata      360

gttattacct ttgaatctgg gcgtccagac caaatgatcc tggagaagtc tctcgattat      420

ggacgaacat ggcagcccta tcagtattat gccacagact gcttagatgc ttttcacatg      480

gatcctaaat ccgtgaagga tttatcacag catacggtct tagaaatcat ttgcacagaa      540

gagtactcaa cagggtatac aacaaatagc aaaataatcc actttgaaat caaagacagg      600

ttcgcgtttt ttgctggacc tcgcctacgc aatatggctt ccctctacgg acagctggat      660

acaaccaaga aactcagaga tttctttaca gtcacagacc tgaggataag gctgttaaga      720

ccagccgttg gggaaatatt tgtagatgag ctacacttgg cacgctactt ttacgcgatc      780

tcagacataa aggtgcgagg aaggtgcaag tgtaatctcc atgccactgt atgtgtgtat      840

gacaacagca aattgacatg cgaatgtgag cacaacacta caggtccaga ctgtgggaaa      900

tgcaagaaga attatcaggg ccgaccttgg agtccaggct cctatctccc catccccaaa      960

ggcactgcaa atacctgtat ccccagtatt tccagtattg gtacgaatgt ctgcgacaac     1020

gagctcctgc actgccagaa cggagggacg tgccacaaca acgtgcgctg cctgtgcccg     1080

gccgcataca cgggcatcct ctgcgagaag ctgcggtgcg aggaggctgg cagctgcggc     1140

tcc                                                                   1143


<210>  4114
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  4114
gactatgaca tctgcaaatc ctgggtgacc acagatgagg gccccacctg ggagttctac       60

gcctgccagc ccaaggtgat gcgcctgaag gactacgtca aggtgaaggt ggagccctca      120

ggcatcacat gtggagaccc ccctgagagg ttctgctccc atgagaatcc ctacctatgc      180

agcaacgagt gtgacgcctc caacccggac ctggcccacc cgcccaggct catgttcgac      240

aaggaggagg agggcctggc cacctactgg cagagcatca cctggagccg ctaccccagc      300

ccgctggaag ccaacatcac cctttcgtgg aacaagaccg tggagctgac cgacgacgtg      360

gtgatgacct tcgagtacgg ccggcccacg gtcatggtcc tggagaagtc cctggacaac      420

gggcgcacct ggcagcccta ccagttctac gccgaggact gcatggaggc cttcggtatg      480

tccgcccgcc gggcccgcga catgtcatcc tccagcgcgc accgcgtgct ctgcaccgag      540

gagtactcgc gctgggcagg ctccaagaag gagaagcacg tgcgcttcga ggtgcgggac      600

cgcttcgcca tctttgccgg ccccgacctg cgcaacatgg acaacctcta cacgcggctg      660

gagagcgcca agggcctcaa ggagttcttc accctcaccg acctgcgcat gcggctgctg      720

cgcccggcgc tgggcggcac ctatgtgcag cgggagaacc tctacaagta cttctacgcc      780

atctccaaca tcgaggtcat cggcaggtgc aagtgcaacc tgcatgccaa cctgtgctcc      840

atgcgcgagg gcagcctgca gtgcgagtgc gagcacaaca ccaccggccc cgactgcggc      900

aagtgcaaga agaatttccg cacccggtcc tggcgggccg gctcctacct gccgctgccc      960

catggctctc ccaacgcctg tgccgctgca ggttcctttg gcaactgcga atgctacggt     1020

cactccaacc gctgcagcta cattgacttc ctgaatgtgg tgacctgcgt cagctgcaag     1080

cacaacacgc gaggtcagca ctgccagcac tgccggctgg gctactaccg caacggctcg     1140

gcagagctgg atgatgagaa cgtctgcatt gagtgtaact gcaaccagat aggctccgtg     1200

cacgaccggt gcaacgagac cggcttctgc gagtgccgcg agggcgcggc gggccccaag     1260

tgcgacgact gcctccccac gcactactgg cgccagggct gctaccccaa cgtgtgcgac     1320

gacgaccagc tgctgtgcca gaacggaggc acctgcctgc agaaccagcg ctgcgcctgc     1380

ccgcgcggct acaccggcgt gcgctgcgag cagccccgct gcgaccccgc cgacgatgac     1440

ggcggtctgg actgcgaccg cgcgcccggg                                      1470


<210>  4115
<211>  1173
<212>  DNA
<213>  Homo Sapiens

<400>  4115
gccgcaccct gccccgatgc ctgctgcccc cacggctcct cgggactgcg atgcacccgg       60

gatggggccc tggatagcct ccaccacctg cccggcgcag agaacctgac tgagctctac      120

atcgagaacc agcagcatct gcagcatctg gagctccgtg atctgagggg cctgggggag      180

ctgagaaacc tcaccatcgt gaagagtggt ctccgtttcg tggcgccaga tgccttccat      240

ttcactcctc ggctcagtcg cctgaatctc tccttcaacg ctctggagtc tctctcctgg      300

aaaactgtgc agggcctctc cttacaggaa ctggtcctgt cggggaaccc tctgcactgt      360

tcttgtgccc tgcgctggct acagcgctgg gaggaggagg gactgggcgg agtgcctgaa      420

cagaagctgc agtgtcatgg gcaagggccc ctggcccaca tgcccaatgc cagctgtggt      480

gtgcccacgc tgaaggtcca ggtgcccaat gcctcggtgg atgtggggga cgacgtgctg      540

ctgcggtgcc aggtggaggg gcggggcctg gagcaggccg gctggatcct cacagagctg      600

gagcagtcag ccacggtgat gaaatctggg ggtctgccat ccctggggct gaccctggcc      660

aatgtcacca gtgacctcaa caggaagaac gtgacgtgct gggcagagaa cgatgtgggc      720

cgggcagagg tctctgttca ggtcaacgtc tccttcccgg ccagtgtgca gctgcacacg      780

gcggtggaga tgcaccactg gtgcatcccc ttctctgtgg atgggcagcc ggcaccgtct      840

ctgcgctggc tcttcaatgg ctccgtgctc aatgagacca gcttcatctt cactgagttc      900

ctggagccgg cagccaatga gaccgtgcgg cacgggtgtc tgcgcctcaa ccagcccacc      960

cacgtcaaca acggcaacta cacgctgctg gctgccaacc ccttcggcca ggcctccgcc     1020

tccatcatgg ctgccttcat ggacaaccct ttcgagttca accccgagga ccccatccct     1080

gtctccttct cgccggtgga cactaacagc acatctggag acccggtgga gaagaaggac     1140

gaaacacctt ttggggtctc ggtggctgtg ggc                                  1173


<210>  4116
<211>  1197
<212>  DNA
<213>  Homo Sapiens

<400>  4116
tgtcccacgt cctgcaaatg cagtgcctct cggatctggt gcagcgaccc ttctcctggc       60

atcgtggcat ttccgagatt ggagcctaac agtgtagatc ctgagaacat caccgaaatt      120

ttcatcgcaa accagaaaag gttagaaatc atcaacgaag atgatgttga agcttatgtg      180

ggactgagaa atctgacaat tgtggattct ggattaaaat ttgtggctca taaagcattt      240

ctgaaaaaca gcaacctgca gcacatcaat tttacccgaa acaaactgac gagtttgtct      300

aggaaacatt tccgtcacct tgacttgtct gaactgatcc tggtgggcaa tccatttaca      360

tgctcctgtg acattatgtg gatcaagact ctccaagagg ctaaatccag tccagacact      420

caggatttgt actgcctgaa tgaaagcagc aagaatattc ccctggcaaa cctgcagata      480

cccaattgtg gtttgccatc tgcaaatctg gccgcaccta acctcactgt ggaggaagga      540

aagtctatca cattatcctg tagtgtggca ggtgatccgg ttcctaatat gtattgggat      600

gttggtaacc tggtttccaa acatatgaat gaaacaagcc acacacaggg ctccttaagg      660

ataactaaca tttcatccga tgacagtggg aagcagatct cttgtgtggc ggaaaatctt      720

gtaggagaag atcaagattc tgtcaacctc actgtgcatt ttgcaccaac tatcacattt      780

ctcgaatctc caacctcaga ccaccactgg tgcattccat tcactgtgaa aggcaacccc      840

aaaccagcgc ttcagtggtt ctataacggg gcaatattga atgagtccaa atacatctgt      900

actaaaatac atgttaccaa tcacacggag taccacggct gcctccagct ggataatccc      960

actcacatga acaatgggga ctacactcta atagccaaga atgagtatgg gaaggatgag     1020

aaacagattt ctgctcactt catgggctgg cctggaattg acgatggtgc aaacccaaat     1080

tatcctgatg taatttatga agattatgga actgcagcga atgacatcgg ggacaccacg     1140

aacagaagta atgaaatccc ttccacagac gtcactgata aaaccggtcg ggaacat        1197


<210>  4117
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  4117
tgccctgcaa attgtgtctg cagcaagact gagatcaatt gccggcggcc ggacgatggg       60

aacctcttcc ccctcctgga agggcaggat tcagggaaca gcaatgggaa cgccagtatc      120

aacatcacgg acatctcaag gaatatcact tccatacaca tagagaactg gcgcagtctt      180

cacacgctca acgccgtgga catggagctc tacaccggac ttcaaaagct gaccatcaag      240

aactcaggac ttcggagcat tcagcccaga gcctttgcca agaaccccca tttgcgttat      300

ataaacctgt caagtaaccg gctcaccaca ctctcgtggc agctcttcca gacgctgagt      360

cttcgggaat tgcagttgga gcagaacttt ttcaactgca gctgtgacat ccgctggatg      420

cagctctggc aggagcaggg ggaggccaag ctcaacagcc agaacctcta ctgcatcaac      480

gctgatggct cccagcttcc tctcttccgc atgaacatca gtcagtgtga ccttcctgag      540

atcagcgtga gccacgtcaa cctgaccgta cgagagggtg acaatgctgt tatcacttgc      600

aatggctctg gatcacccct tcctgatgtg gactggatag tcactgggct gcagtccatc      660

aacactcacc agaccaatct gaactggacc aatgttcatg ccatcaactt gacgctggtg      720

aatgtgacga gtgaggacaa tggcttcacc ctgacgtgca ttgcagagaa cgtggtgggc      780

atgagcaatg ccagtgttgc cctcactgtc tactatcccc cacgtgtggt gagcctggag      840

gagcctgagc tgcgcctgga gcactgcatc gagtttgtgg tgcgtggcaa ccccccacca      900

acgctgcact ggctgcacaa tgggcagcct ctgcgggagt ccaagatcat ccatgtggaa      960

tactaccaag agggagagat ttccgagggc tgcctgctct tcaacaagcc cacccactac     1020

aacaatggca actataccct cattgccaaa aacccactgg gcacagccaa ccagaccatc     1080

aatggccact tcctcaagga gccctttcca gagagcacgg ataactttat cttgtttgac     1140

gaagtgagtc ccacacctcc tatcactgtg acccacaaac cagaagaaga cact           1194


<210>  4118
<211>  1215
<212>  DNA
<213>  Homo Sapiens

<400>  4118
atgtcctccc cagcactgac ggcaggtgct tcaggaaagg tgatggactt caacaatggc       60

acctacctgg tcagcttcac tctgttctgg gagggccagg tctccctgtc tctgctgctc      120

atccacccca gtgaaggggc gtcggctctc tggagggcaa ggaaccaagg ctatgataaa      180

attattttca aaggcaaatt tgttaatggc acctctcatg tcttcactga atgtggcctg      240

accctaaact caaatgctga actctgtgaa tatctggatg acagagacca agaagccttc      300

tattgtatga agcctcaaca catgccctgt gaggctctga cctacatgac cacccggaat      360

agagaggtat cttatcttac agacaaggaa aacagccttt tccacaggtc caaagtggga      420

gttgaaatga tgaaggatcg taaacacatt gatgtcacta attgtaacaa gagagaaaaa      480

atagaagaga catgccaagt tggaatgaag cctcctgtcc ctggtggtta tactttacaa      540

ggaaaatgga taacaacatt ttgcaaccag gttcagttag acacaattaa gataaatggc      600

tgtttgaaag gcaaactcat ttacctcctg ggagactcta cactacgtca gtggatctac      660

tacttcccca aagttgtaaa aacactgaag ttttttgatc ttcatgaaac tggaatcttt      720

aagaaacatt tgcttctgga tgcagaaaga cacactcaga ttcaatggaa aaaacatagc      780

tatcccttcg tcactttcca gctctactct ctgatagatc atgattatat ccctcgggaa      840

attgaccggc tatcaggtga caaaaacaca gccatcgtca tcacctttgg ccagcacttt      900

agaccatttc ccattgacat ttttattcgc agggccatcg gtgttcaaaa ggctattgaa      960

agactgttcc taagaagccc agccactaaa gtgattatta agacagaaaa catcagggag     1020

atgcacatag agacagagag gtttgtagac ttccatggtt atattcacta tcttatcatg     1080

aaggatattt tcaaagacct caacgtgggc atcattgatg cctgggacat gaccattgca     1140

tatggcactg acactatcca cccacctgat catgtgattg gaaatcagat taacatgttc     1200

ttaaactaca tttgc                                                      1215


<210>  4119
<211>  1587
<212>  DNA
<213>  Homo Sapiens

<400>  4119
gagtacttgg accatgagac tgtttcagcc actttcatcg acagcagtgg acagtttgtt       60

tcctcccagg tgacaggaat tagccgaaat ccctactgtg gctatgatca gcagaccctg      120

tccagccagg agcgcatgga ggaggactcc ttgctggctg ccttgcaccg gcaggttcct      180

gatgtgggcc cagtcccctt tgtgaagagc actgaccctt cttccagcta ctttgtcatc      240

ttgaactctg ctgccttctt taaggtggga agccagcttg aggtgctggt tcatgtgcag      300

gattttcaaa gaaagcccaa gaagtatggt ggagactacc tgcaggccag aattcactcc      360

ctcaagctgc aggctggggc tgtgggcagg gtggtggatt accagaatgg gttttacaag      420

gttttcttta ctttgctatg gccaggcaaa gttaaagtat ccgtatctct ggtccacccc      480

agtgaaggga tcagagttct tcagcgctta caggaagata aaccagacag ggtctatttc      540

aagagtctct tccgttcagg aagaatttct gaaactactg agtgcaacgt gtgtcttcct      600

gggaatctgc ccctgtgtaa ctttacagac ctctacactg gggagccctg gttctgcttc      660

aaaccaaaga agctcccttg cagcagcaga attacccatt tcaaaggtgg atacctgaaa      720

ggtctcctaa ccgctgcaga gagtgctttc ttccagagtg gtgtcaatat caaaatgcca      780

gtcaactcca gtggacctga ttgggtaact gtgattccca ggagaataaa agaaactaac      840

agtctagaac tatctcaagg ctcaggaact tttccttctg ggtattatta taaagaccag      900

tggaggccca gaaagtttaa gatgcgtcag tttaatgacc ctgacaacat tacagagtgc      960

ttacaaagaa aagtggtgca tttatttggt gactcaacaa tcaggcaatg gtttgaatac     1020

cttactacat ttgttccaga tttagtggag tttaacttgg gtagtcccaa gaatgtgggt     1080

cccttccttg cagtggacca gaagcacaac atcctgctca aataccgctg ccatggtcca     1140

cccatccgct tcacgactgt ctttagcaat gagctccatt atgtggcgaa tgagctgaat     1200

ggcattgtgg gagggaagaa cacagtggtt gccatagctg tatggtctca cttcagcacc     1260

ttccctttgg aagtgtacat ccggcggctc aggaacatcc gtcgagcagt ggttcggctc     1320

ctcgatcgaa gcccaaagac cgtggtggtc atccggacgg ccaacgccca agagctggga     1380

cctgaggtga gccttttcaa cagcgactgg tacaactttc agctggacac catccttcgg     1440

aggatgttct caggggttgg agtatatctc gtcgatgcct gggagatgac cctggcccat     1500

tatctaccgc acaagctgca tccagatgaa gttattgtga agaaccagct ggacatgttc     1560

ttgtcctttg tgtgcccctt ggaaacc                                         1587


<210>  4120
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  4120
caaaattcaa cgaaagtgtg gtcagccctg aacctatcca tcagcctgca ttattggaac       60

aactccacaa agtccctatt tcctaagacg cctttaatct ctctgaagcc tcttacggaa      120

actgaactgc gtattaaaga gataatagaa aagctggatc aacaaatccc accgaggccg      180

ttcactcacg tgaacaccac cacaagtgct acccactcca cggccacaat ccttaatcct      240

cgtgacacgt actgcagggg tgaccagttg cacatattat tggaggttcg tgaccatcta      300

ggcaggagga aacagtatgg cggtgatttc ttgagggcaa gaatgagctc tccggcgtta      360

atggccggag ccagtggtaa agtcacagac tttaacaacg ggacctattt agtaagcttc      420

acgctgtttt gggaaggtca agtcagccta agcctgctgc tgatccaccc aagcgagggc      480

gtatctgccc tgtggtcagc gaggaatcag ggctacgata gagtcatatt tactggccag      540

ttcgttaatg ggacctccca ggtacacagt gaatgtgggt taattcttaa tacaaacgcc      600

gaactatgcc aatacttaga caacagggat caggagggat tctactgcgt acgtcctcag      660

catatgccct gcgctgcact tacgcatatg tatagcaaaa acaagaaagt ttcttattta      720

tccaaacaag aaaagtccct gttcgagagg tctaatgttg gtgttgagat catggaaaaa      780

tttaatacca tctctgtgag caagtgtaat aaagaaacgg ttgcaatgaa agaaaagtgc      840

aaattcggta tgacaagtac gattcccagt ggacacgttt ggcgtaatac atggaatcca      900

gtatcctgct cattagccac cgtgaagatg aaggagtgcc tacgtggcaa gttgatatat      960

ctgatggggg acagcacaat aagacaatgg atggagtatt ttaaagcttc tatcaatacg     1020

ttgaagtcag tggatctgca tgagagtggt aagttacagc accaactggc cgttgatctg     1080

gataggaaca ttaacatcca gtggcaaaag tactgctacc ccttaattgg atctatgact     1140

tatagcgtaa aagaaatgga atatttaact agggctatcg ataggaccgg tggtgagaaa     1200

aatactgtca tcgtaatctc attaggccaa cattttaggc cattccctat cgacgtgttt     1260

atcaggcgtg ctttaaacgt tcataaagcg attcaacatt tgctgctgag gagccccgat     1320

acaatggtaa ttatcaaaac agagaacatt agggaaatgt acaacgacgc tgaaaggttc     1380

tccgactttc acggttatat tcaatatctg atcattaaag atatattcca ggacttatca     1440

gtttccatca tcgatgcctg ggatataact atcgcttatg gcacgaacaa cgtgcatccc     1500

ccgcagcatg tggtcggaaa tcagataaac attctattga attacatttg t              1551


<210>  4121
<211>  1374
<212>  DNA
<213>  Homo Sapiens

<400>  4121
gtgggggcct gcgcccgcgc ttgtcccgcc gcctgcgcct gcagcaccgt ggagcgcggc       60

tgctcggtgc gctgcgaccg cgcgggcctc ctgcgggtgc cggccgagct cccgtgcgag      120

gcggtctcca tcgacctgga ccggaacggc ctgcgcttcc tgggcgagcg agccttcggc      180

acgctgccgt ccttgcgccg cctgtcgctg cgccacaaca acctgtcctt catcacgccc      240

ggcgccttca agggcctgcc gcgcctggct gagctgcgcc tggcgcacaa cggcgacctg      300

cgctacctgc acgcgcgcac cttcgcggcg ctcagccgcc tgcgccgcct agacctagca      360

gcctgccgcc tcttcagcgt gcccgagcgc ctcctggccg aactgccggc cctgcgcgaa      420

ctcgccgcct tcgacaacct gttccgccgc gtgccgggcg cgctgcgcgg cctggccaac      480

ctgacgcacg cgcacctgga gcgcggccgc atcgaggcgg tggcctccag ctcgctgcag      540

ggcctgcgcc gcctgcgctc gctcagcctg caggccaacc gcgtccgtgc cgtgcacgct      600

ggcgccttcg gggactgtgg cgtcctggag catctgctgc tcaacgacaa cctgctggcc      660

gagctcccgg ccgacgcctt ccgcggcctg cggcgcctgc gcacgctcaa cctgggtggc      720

aacgcgctgg accgcgtggc gcgcgcctgg ttcgctgacc tggccgagct cgagctgctc      780

tacctggacc gcaacagcat cgccttcgtg gaggagggcg ccttccagaa cctctcgggt      840

ctcctcgcgc tgcacctcaa cggcaaccgc ctcaccgtgc tcgcctgggt cgccttccag      900

cccggcttct tcctgggccg cctcttcctc ttccgcaacc cgtggtgctg cgactgccgt      960

ctggagtggc tgagggactg gatggagggc tccggacgtg tcaccgacgt gccgtgcgcc     1020

tccccgggct ccgtggccgg cctggacctc agccaggtga ccttcgggcg ctcctccgat     1080

ggcctctgtg tggaccccga ggagctgaac ctcaccacgt ccagtccagg cccgtcccca     1140

gaaccagcgg ccaccaccgt gagcaggttc agcagcctcc tctccaagct gctggccccg     1200

agggtcccgg tggaggaggc ggccaacacc actggggggc tggccaacgc ctccctgtcc     1260

gacagcctct cctcccgtgg ggtgggaggc gcgggccggc agccctggtt tctcctcgcc     1320

tcttgtctcc tgcccagcgt ggcccagcac gtggtgtttg gcctgcagat ggac           1374


<210>  4122
<211>  834
<212>  DNA
<213>  Homo Sapiens

<400>  4122
ccaccaaccc agcaggactc acgcattatc tatgattatg gaacagataa ttttgaagaa       60

tccatattta gccaagatta tgaggataaa tacctggatg gaaaaaatat taaggaaaaa      120

gaaactgtga taatacccaa tgagaaaagt cttcaattac aaaaagatga ggcaataaca      180

ccattacctc ccaagaaaga aaatgatgaa atgcccacgt gtctgctgtg tgtttgttta      240

agtggctctg tatactgtga agaagttgac attgatgctg taccaccctt accaaaggaa      300

tcagcctatc tttacgcacg attcaacaaa attaaaaagc tgactgccaa agattttgca      360

gacataccta acttaagaag actcgatttt acaggaaatt tgatagaaga tatagaagat      420

ggtacttttt caaaactttc tctgttagaa gaactttcac ttgctgaaaa tcaactacta      480

aaacttccag ttcttcctcc caagctcact ttatttaatg caaaatacaa caaaatcaag      540

agtaggggaa tcaaagcaaa tgcattcaaa aaactgaata acctcacctt cctctacttg      600

gaccataatg ccctggaatc cgtgcctctt aatttaccag aaagtctacg tgtaattcat      660

cttcagttca acaacatagc ttcaattaca gatgacacat tctgcaaggc taatgacacc      720

agttacatcc gggaccgcat tgaagagata cgcctggagg gcaatccaat cgtcctggga      780

aagcatccaa acagttttat ttgcttaaaa agattaccga tagggtcata cttt            834


<210>  4123
<211>  1569
<212>  DNA
<213>  Homo Sapiens

<400>  4123
gacccctgtt ctgcctatat aagtcttaac gagccgtgga ggaatacgga tcaccaattg       60

gatgaaagtc aggggccacc actgtgcgat aaccacgtaa acggcgagtg gtaccatttc      120

actgggatgg ctggagatgc gatgcccaca ttctgtattc ccgagaatca ctgcggtaca      180

cacgccccgg tatggttgaa tgggagtcat cccctagagg gcgacggcat cgtacaaagg      240

caagcgtgtg catcatttaa cgggaactgt tgcctttgga acacgaccgt tgaggtgaaa      300

gcttgccccg gcgggtatta cgtctaccgt ctaacaaagc ccagcgtttg ttttcatgtg      360

tattgtgggc atttttacga catctgcgat gaggactgcc acggctcctg ttccgacact      420

tccgaatgta cgtgcgcccc agggactgta ttgggccccg accgtcagac ttgtttcgac      480

gaaaacgagt gtgaacagaa caacggtgga tgctctgaga tttgtgtcaa tctgaagaac      540

agttatcgtt gtgaatgcgg agtgggccgt gtcctgcgta gcgacggcaa gacgtgcgaa      600

gacgtcgagg ggtgccataa caataatggc ggctgtagtc actcttgttt aggatcagaa      660

aaaggctatc aatgcgagtg tccgaggggg cttgttttat ctgaggataa tcacacatgc      720

caagttcccg ttttatgtaa aagcaacgcc atagaagtaa atattcctag agagctggtg      780

ggtgggctgg agctgtttct gaccaatacc agttgtagag gagtctctaa tggtacgcac      840

gtaaatattc tttttagtct taaaacttgt ggaaccgtgg tagacgttgt taatgataag      900

atagtagcat ctaacttggt gactgggttg ccaaaacaga caccagggag ttctggtgat      960

ttcatcataa gaacatctaa actattaatt ccggttactt gtgaattccc cagactgtat     1020

accatatcag aaggttatgt gcccaatttg agaaatagcc cgttggagat tatgagtcgt     1080

aaccacggga tatttccgtt caccttagaa attttcaaag acaatgaatt tgaagaacca     1140

tatcgtgaag cattgcccac tttgaaacta cgtgattcat tgtactttgg catcgagcca     1200

gtcgtccatg ttagcggctt ggaatccctt gttgagtctt gcttcgcgac acccacatcc     1260

aagatcgacg aggtacttaa atattattta atccgtgacg ggtgcgtgtc cgacgattcc     1320

gtaaagcagt atacaagcag agaccatctt gcgaaacatt ttcaggtccc ggtcttcaaa     1380

tttgttggta aagaccacaa agaagtgttc ctacactgtc gtgtgcttgt ctgtggcgta     1440

ctagatgaga ggtcccgttg tgcacaagga tgtcatagaa gaatgaggcg tggtgccggc     1500

ggggaggatt ccgctggtct gcaaggacag actcttacgg gtggcccgat tcgtatcgat     1560

tgggaggat                                                             1569


<210>  4124
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  4124
atgcaattat cccaggtgtc tgacctccta acacaagagc aagcaaacct aactcaccag       60

aaaaagaaac tggagggaca gatctcagcc cggcaacaag cagaagaagc ttcacaggag      120

tcagaaaacg aactcaagga aatgatagaa acccttgctc ggaagctgaa tgagaaatcc      180

aaagagcaaa tggaacttca ccaccagaat ctgaatctcc aagaaacact gaagagagta      240

gcaaattgtt cagctccttg tccgcaagac tggatctggc atggagaaaa ctgttaccta      300

ttttcctcgg gctcatttaa ctgggaaaag agccaagaga agtgcttgtc tttggatgcc      360

aagttgctga aaattaatag cacagctgat ctggacttca tccagcaagc aatttcctat      420

tccagttttc cattctggat ggggctgtct cggaggaacc ccagctaccc atggctctgg      480

gaggacggtt ctcctttgat gccccactta tttagagtcc gaggcgctgt ctcccagaca      540

tacccttcag gtacctgtgc atatatacaa cgaggagctg tttatgcgga aaactgcatt      600

ttagctgcct tcagtatatg tcagaagaag gcaaacctaa gagcacag                   648


<210>  4125
<211>  1203
<212>  DNA
<213>  Homo Sapiens

<400>  4125
caatatgaaa cttatcagtg ggatgaagac tatgaccaag agccagatga tgattaccaa       60

acaggattcc catttcgtca aaatgtagac tacggagttc cttttcatca gtatacttta      120

ggctgtgtca gtgaatgctt ctgtccaact aactttccat catcaatgta ctgtgataat      180

cgcaaactca agactatccc aaatattccg atgcacattc agcaactcta ccttcagttc      240

aatgaaattg aggctgtgac tgcaaattca ttcatcaatg caactcatct taaagaaatt      300

aacctcagcc acaacaaaat taaatctcaa aagattgatt atggtgtgtt tgctaagctt      360

ccaaatctac tacaacttca tctagagcat aataatttag aagaatttcc atttcctctt      420

cctaaatctc tggaaagact ccttcttggt tacaatgaaa tctccaaact gcagacaaat      480

gctatggatg ggctagtaaa cttgaccatg cttgatctct gttataatta tcttcatgat      540

tctctgctaa aagacaaaat ctttgccaaa atggaaaaac taatgcagct caacctctgc      600

agtaacagat tagaatcaat gcctcctggt ttgccttctt cacttatgta tctgtcttta      660

gaaaataatt caatttcttc tatacccgaa aaatacttcg acaaacttcc aaaacttcat      720

actctaagaa tgtcacacaa caaactacaa gacatcccat ataatatttt taatcttccc      780

aacattgtag aactcagtgt tggacacaac aaattgaagc aagcattcta tattccaaga      840

aatttggaac acctatacct acaaaataat gaaatagaaa agatgaatct tacagtgatg      900

tgtccttcta ttgacccact acattaccac catttaacat acattcgtgt ggaccaaaat      960

aaactaaaag aaccaataag ctcatacatc ttcttctgct tccctcatat acacactatt     1020

tattatggtg aacaacgaag cactaatggt caaacaatac aactaaagac acaagttttc     1080

aggagatttc cagatgatga tgatgaaagt gaagatcacg atgatcctga caatgctcat     1140

gagagcccag aacaagaagg agcagaaggg cactttgacc ttcattatta tgaaaatcaa     1200

gaa                                                                   1203


<210>  4126
<211>  1179
<212>  DNA
<213>  Homo Sapiens

<400>  4126
atttgtcctc tccaatgtat atgcacagag aggcacaggc atgtggactg ttcaggcaga       60

aacttgtcta cattaccatc tggactgcaa gagaatatta tacatttaaa cctgtcttat      120

aaccacttta ctgatctgca taaccagtta acccaatata ccaatctgag gaccctggac      180

atttcaaaca acaggcttga aagcctgcct gctcacttac ctcggtctct gtggaacatg      240

tctgctgcta acaacaacat taaacttctt gacaaatctg atactgctta tcagtggaat      300

cttaaatatc tggatgtttc taagaacatg ctggaaaagg ttgtcctcat taaaaataca      360

ctaagaagtc tcgaggttct caacctcagt agtaacaaac tttggacagt tccaaccaac      420

atgccctcca aactacatat cgtggacctg tctaataatt ctttgacaca aattcttcca      480

ggtacattaa taaacctgac aaatctcaca catctttacc tgcacaacaa taagttcaca      540

ttcattccag accaatcttt tgaccaactc tttcagttgc aagagataac cctttacaat      600

aacaggtggt catgtgacca caaacaaaac attacttact tactgaagtg gatgatggaa      660

acaaaagccc atgtgatagg gactccatgt tctacccaaa tatcatcttt aaaggaacat      720

aacatgtatc ccacaccttc tggatttacc tcaagcttat tcactgtaag tgggatgcag      780

acagtggaca ccattaactc tctgagtgtg gtaactcaac ccaaagtgac caaaataccc      840

aaacaatatc gaacaaagga aacaacgttt ggtgccactc taagcaaaga caccaccttt      900

actagcactg ataaggcttt tgtgccctat ccagaagata catccacaga gactatcaat      960

tcacatgaag cagcagctgc aactctaact attcatctcc aagatggaat ggtcacaaac     1020

acaagcctca ctagctcaac aaaatcatcc ccaacaccca tgaccctaag tatcactagt     1080

ggcatgccaa ataatttctc tgaaatgcct caacaaagca caacccttaa cttatggagg     1140

gaagagacaa ccacaaatgt aaagactcca ttaccttct                            1179


<210>  4127
<211>  885
<212>  DNA
<213>  Homo Sapiens

<400>  4127
ggagtgcccg tgcgcagcgg agatgccacc ttccccaaag ctatggacaa cgtgacggtc       60

cggcaggggg agagcgccac cctcaggtgt accatagatg accgggtaac ccgggtggcc      120

tggctaaacc gcagcaccat cctctacgct gggaatgaca agtggtccat agaccctcgt      180

gtgatcatcc tggtcaatac accaacccag tacagcatca tgatccaaaa tgtggatgtg      240

tatgacgaag gtccgtacac ctgctctgtg cagacagaca atcatcccaa aacgtcccgg      300

gttcacctaa tagtgcaagt tcctcctcag atcatgaata tctcctcaga catcactgtg      360

aatgagggaa gcagtgtgac cctgctgtgt cttgctattg gcagaccaga gccaactgtg      420

acatggagac acctgtcagt caaggaaggc cagggctttg taagtgagga tgagtacctg      480

gagatctctg acatcaagcg agaccagtcc ggggagtacg aatgcagcgc gttgaacgat      540

gtcgctgcgc ccgatgtgcg gaaagtaaaa atcactgtaa actatcctcc ctatatctca      600

aaagccaaga acactggtgt ttcagtcggt cagaagggca tcctgagctg tgaagcctct      660

gcagtcccca tggctgaatt ccagtggttc aaggaagaaa ccaggttagc cactggtctg      720

gatggaatga ggattgaaaa caaaggccgc atgtccactc tgactttctt caatgtttca      780

gaaaaggatt atgggaacta tacttgtgtg gccacgaaca agcttgggaa caccaatgcc      840

agcatcacat tgtatgggcc tggagcagtc attgatggtg taaac                      885


<210>  4128
<211>  939
<212>  DNA
<213>  Homo Sapiens

<400>  4128
gcttctctcc caaggaagga gaggaagagg agagaggagc agatgcccag ggaaggcgat       60

tcctttgaag ttctgcctct gcggaatgat gtcctgaacc cagacaacta tggtgaagtc      120

attgacctga gcaactatga ggagctcaca gattatgggg accaactccc cgaggttaag      180

gtgactagcc tcgctcctgc aaccagcatc agtcccgcca agagcactac ggctccaggg      240

acaccctcgt caaaccccac gatgaccaga cctactacag cagggctgct actgagttcc      300

cagcccaacc atggtctgcc cacctgcctg gtctgcgtgt gcctcggttc ctctgtgtat      360

tgcgatgaca ttgacctaga ggacattcct cctcttcctc ggaggactgc ctacctgtat      420

gcacgcttca accgcatcag ccgtatcagg gccgaagact tcaaagggct gacaaagttg      480

aagaggattg acctctccaa caacctcatt tcctccatcg ataatgatgc cttccgcctg      540

ctacatgccc tccaggacct catcctccca gagaaccagt tggaagctct gcccgtgctg      600

cccagtggca ttgagttcct ggatgtccgc ctaaatcggc tccagagctc ggggatacag      660

cctgcagcct tcagggcaat ggagaagctg cagttccttt acctgtcaga caacctgctg      720

gattctatcc cagggccttt gcccctgagc ctgcgctctg tacacctgca gaataacctg      780

atagagacca tgcagagaga cgtcttctgt gaccccgagg agcacaaaca cacccgcagg      840

cagctggaag acatccgcct ggatggcaac cccatcaacc tcagcctctt ccccagcgcc      900

tacttctgcc tgcctcggct ccccatcggc cgcttcacg                             939


<210>  4129
<211>  792
<212>  DNA
<213>  Homo Sapiens

<400>  4129
gacatcactc cgtctgtccc cccagcttca taccacccta agccatggct gggagctcag       60

ccggctacag ttgtgacccc tggggtcaac gtgaccttga gatgccgggc accccaaccc      120

gcttggagat ttggactttt caagcctgga gagatcgctc cccttctctt ccgggatgtg      180

tcctccgagc tggcagaatt ctttctggag gaggtgactc cagcccaagg gggaagttac      240

cgctgctgct accgaaggcc agactggggg ccgggtgtct ggtcccagcc cagcgatgtc      300

ctggagctgc tggtgacaga ggagctgccg cggccgtcgc tggtggcgct gcccgggccg      360

gtggtgggtc ctggcgccaa cgtgagcctg cgctgcgcgg gccgcctgcg gaacatgagc      420

ttcgtgctgt accgcgaggg cgtggcggcc ccgctgcagt accgccactc cgcgcagccc      480

tgggccgact tcacgctgct gggcgcccgc gcccccggca cctacagctg ctactatcac      540

acgccctccg cgccctacgt gctgtcgcag cgcagcgagg tactggtcat cagctgggaa      600

ggtgagggcc ctgaggcccg gcccgcctcc tccgccccag gaatgcaggc cccaggacct      660

ccgccctcag acccaggagc ccaggccccc agcctctcct ccttcagacc caggggtcta      720

gtcctgcagc ccctcctccc tcagacccag gattcctggg acccagcccc tcctccctca      780

gatccaggag tc                                                          792


<210>  4130
<211>  2139
<212>  DNA
<213>  Homo Sapiens

<400>  4130
gaacgtttac cattgactcc tgtatcactt aaagtttcca ccaattctac gcgtcagagt       60

ttgcacttac aatggactgt ccacaacctt ccttatcatc aggaattgaa aatggtattt      120

cagatccaga tcagtaggat tgaaacatcc aatgtcatct gggtggggaa ttacagcacc      180

actgtgaagt ggaaccaggt tctgcattgg agctgggaat ctgagctccc tttggaatgt      240

gccacacact ttgtaagaat aaagagtttg gtggacgatg ccaagttccc tgagccaaat      300

ttctggagca actggagttc ctgggaggaa gtcagtgtac aagattctac tggacaggat      360

atattgttcg ttttccctaa agataagctg gtggaagaag gcaccaatgt taccatttgt      420

tacgtttcta ggaacattca aaataatgta tcctgttatt tggaagggaa acagattcat      480

ggagaacaac ttgatccaca tgtaactgca ttcaacttga atagtgtgcc tttcattagg      540

aataaaggga caaatatcta ttgtgaggca agtcaaggaa atgtcagtga aggcatgaaa      600

ggcatcgttc tttttgtctc aaaagtactt gaggagccca aggacttttc ttgtgaaacc      660

gaggacttca agactttgca ctgtacttgg gatcctggga cggacactgc cttggggtgg      720

tctaaacaac cttcccaaag ctacacttta tttgaatcat tttctgggga aaagaaactt      780

tgtacacaca aaaactggtg taattggcaa ataactcaag actcacaaga aacctataac      840

ttcacactca tagctgaaaa ttacttaagg aagagaagtg tcaatatcct ttttaacctg      900

actcatcgag tttatttaat gaatcctttt agtgtcaact ttgaaaatgt aaatgccaca      960

aatgccatca tgacctggaa ggtgcactcc ataaggaata atttcacata tttgtgtcag     1020

attgaactcc atggtgaagg aaaaatgatg caatacaatg tttccatcaa ggtgaacggt     1080

gagtacttct taagtgaact ggaacctgcc acagagtaca tggcgcgagt acggtgtgct     1140

gatgccagcc acttctggaa atggagtgaa tggagtggtc agaacttcac cacacttgaa     1200

gctgctccct cagaggcccc tgatgtctgg agaattgtga gcttggagcc aggaaatcat     1260

actgtgacct tattctggaa gccattatca aaactgcatg ccaatggaaa gatcctgttc     1320

tataatgtag ttgtagaaaa cctagacaaa ccatccagtt cagagctcca ttccattcca     1380

gcaccagcca acagcacaaa actaatcctt gacaggtgtt cctaccaaat ctgcgtcata     1440

gccaacaaca gtgtgggtgc ttctcctgct tctgtaatag tcatctctgc agaccccgaa     1500

aacaaagagg ttgaggaaga aagaattgca ggcacagagg gtggattctc tctgtcttgg     1560

aaaccccaac ctggagatgt tataggctat gttgtggact ggtgtgacca tacccaggat     1620

gtgctcggtg atttccagtg gaagaatgta ggtcccaata ccacaagcac agtcattagc     1680

acagatgctt ttaggccagg agttcgatat gacttcagaa tttatgggtt atctacaaaa     1740

aggattgctt gtttattaga gaaaaaaaca ggatactctc aggaacttgc tccttcagac     1800

aaccctcacg tgctggtgga tacattgaca tcccactcct tcactctgag ttggaaagat     1860

tactctactg aatctcaacc tggttttata caagggtacc atgtctatct gaaatccaag     1920

gcgaggcagt gccacccacg atttgaaaag gcagttcttt cagatggttc agaatgttgc     1980

aaatacaaaa ttgacaaccc ggaagaaaag gcattgattg tggacaacct aaagccagaa     2040

tccttctatg agtttttcat cactccattc actagtgctg gtgaaggccc cagtgctacg     2100

ttcacgaagg tcacgactcc ggatgaacac tcctcgatg                            2139


<210>  4131
<211>  2148
<212>  DNA
<213>  Homo Sapiens

<400>  4131
ttgccaagag agtacacagt cattaatgaa gcctgccctg gagcagagtg gaatatcatg       60

tgtcgggagt gctgtgaata tgatcagatt gagtgcgtct gccccggaaa gagggaagtc      120

gtgggttata ccatcccttg ctgcaggaat gaggagaatg agtgtgactc ctgcctgatc      180

cacccaggtt gtaccatctt tgaaaactgc aagagctgcc gaaatggctc atgggggggt      240

accttggatg acttctatgt gaaggggttc tactgtgcag agtgccgagc aggctggtac      300

ggaggagact gcatgcgatg tggccaggtt ctgcgagccc caaagggtca gattttgttg      360

gaaagctatc ccctaaatgc tcactgtgaa tggaccattc atgctaaacc tgggtttgtc      420

atccaactaa gatttgtcat gttgagcctg gagtttgact acatgtgcca gtatgactat      480

gttgaggttc gtgatggaga caaccgcgat ggccagatca tcaagcgtgt ctgtggcaac      540

gagcggccag ctcctatcca gagcatagga tcctcactcc acgtcctctt ccactccgat      600

ggctccaaga attttgacgg tttccatgcc atttatgagg agatcacagc atgctcctca      660

tccccttgtt tccatgacgg cacgtgcgtc cttgacaagg ctggatctta caagtgtgcc      720

tgcttggcag gctatactgg gcagcgctgt gaaaatcttc tggaggctgg gaagtccaag      780

atcaaggcgt cagaagattc attgtctgtc cttgaagaaa gaaactgctc agaccctggg      840

ggcccagtca atgggtacca gaaaataaca gggggccctg ggcttatcaa cggacgccat      900

gctaaaattg gcaccgtggt gtctttcttt tgtaacaact cctatgttct tagtggcaat      960

gagaaaagaa cttgccagca gaatggagag tggtcaggga aacagcccat ctgcataaaa     1020

gcctgccgag aaccaaagat ttcagacctg gtgagaagga gagttcttcc gatgcaggtt     1080

cagtcaaggg agacaccatt acaccagcta tactcagcgg ccttcagcaa gcagaaactg     1140

cagagtgccc ctaccaagaa gccagccctt ccctttggag atctgcccat gggataccaa     1200

catctgcata cccagctcca gtatgagtgc atctcaccct tctaccgccg cctgggcagc     1260

agcaggagga catgtctgag gactgggaag tggagtgggc gggcaccatc ctgcatccct     1320

atctgcggga aaattgagaa catcactgct ccaaagaccc aagggttgcg ctggccgtgg     1380

caggcagcca tctacaggag gaccagcggg gtgcatgacg gcagcctaca caagggagcg     1440

tggttcctag tctgcagcgg tgccctggtg aatgagcgca ctgtggtggt ggctgcccac     1500

tgtgttactg acctggggaa ggtcaccatg atcaagacag cagacctgaa agttgttttg     1560

gggaaattct accgggatga tgaccgggat gagaagacca tccagagcct acagatttct     1620

gctatcattc tgcatcccaa ctatgacccc atcctgcttg atgctgacat cgccatcctg     1680

aagctcctag acaaggcccg tatcagcacc cgagtccagc ccatctgcct cgctgccagt     1740

cgggatctca gcacttcctt ccaggagtcc cacatcactg tggctggctg gaatgtcctg     1800

gcagacgtga ggagccctgg cttcaagaac gacacactgc gctctggggt ggtcagtgtg     1860

gtggactcgc tgctgtgtga ggagcagcat gaggaccatg gcatcccagt gagtgtcact     1920

gataacatgt tctgtgccag ctgggaaccc actgcccctt ctgatatctg cactgcagag     1980

acaggaggca tcgcggctgt gtccttcccg ggacgagcat ctcctgagcc acgctggcat     2040

ctgatgggac tggtcagctg gagctatgat aaaacatgca gccacaggct ctccactgcc     2100

ttcaccaagg tgctgccttt taaagactgg attgaaagaa atatgaaa                  2148


<210>  4132
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  4132
atccgctgtc ccaaaggctc caaggcctat ggctcccact gctatgcctt gtttttgtca       60

ccaaaatcct ggacagatgc agatctggcc tgccagaagc ggccctctgg aaacctggtg      120

tctgtgctca gtggggctga gggatccttc gtgtcctccc tggtgaagag cattggtaac      180

agctactcat acgtctggat tgggctccat gaccccacac agggcaccga gcccaatgga      240

gaaggttggg agtggagtag cagtgatgtg atgaattact ttgcatggga gagaaatccc      300

tccaccatct caagccccgg ccactgtgcg agcctgtcga gaagcacagc atttctgagg      360

tggaaagatt ataactgtaa tgtgaggtta ccctatgtct gcaagttcac tgac            414


<210>  4133
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  4133
gctcccaagg tgaggcggca gagtgacacc tggggaccct ggagccagtg gagcccctgc       60

agccggacct gtggaggggg tgtcagcttc cgggagcgcc cctgctactc ccagaggaga      120

gatggaggct ccagctgcgt gggccccgcc cggagccacc gctcttgtcg cacggagagc      180

tgccccgacg gcgcccggga cttccgggcc gagcagtgcg cggagttcga cggagcggag      240

ttccaggggc ggcggtatcg gtggctgccc tactacagcg ccccaaacaa gtgtgaactg      300

aactgcattc ccaaagtgct gggattacag gca                                   333


<210>  4134
<211>  4641
<212>  DNA
<213>  Homo Sapiens

<400>  4134
cgggaggcga ggggcgccac cgaggagccg agcccgccga gccgggcgct ctatttcagc       60

gggcgaggcg agcagctgcg cctccgggcc gacctcgagc tgccccggga cgcgttcacg      120

ctgcaagtgt ggctgcgagc ggaggggggc cagaggtctc cggcagtgat cacagggctg      180

tatgacaaat gttcttatat ctcacgtgac cgaggatggg tcgtgggcat tcacaccatc      240

agtgaccaag acaacaaaga cccacgctac tttttctcct tgaagacaga ccgagcccgg      300

caagtgacca ccatcaatgc ccaccgcagc tacctcccag gccagtgggt atacctagct      360

gccacctatg atgggcagtt catgaagctc tatgtgaatg gtgcccaggt ggccacctct      420

ggggaacaag tgggtggcat attcagccca ctgacccaga agtgcaaagt gctcatgtta      480

gggggcagtg ccctgaatca caactaccgg ggctacatcg agcacttcag tctgtggaag      540

gtggccagga ctcagcggga gatactgtct gacatggaaa cccatggcgc ccacactgct      600

ctacctcagc tcctcctcca ggagaactgg gacaatgtga agcatgcctg gtcccccatg      660

aaggatggca gcagccccaa agtggaattc agcaatgccc acggctttct gctggacacg      720

agtctggagc ctcctctgtg tggacagaca ttgtgtgaca acacagaggt cattgccagc      780

tacaatcagc tctcaagttt ccgccagccc aaggtggtgc gctaccgcgt ggtcaacctc      840

tatgaagatg atcataagaa cccgacggtg acgcgcgagc aggtggactt ccagcaccat      900

cagctggctg aggccttcaa gcaatacaac atctcctggg agctggacgt gctggaggtg      960

agcaactcct ctcttcgccg ccgcctcatc ctggccaact gtgacatcag caagattggg     1020

gatgagaact gtgaccccga gtgcaaccac acgctgacgg gccacgacgg cggggattgc     1080

cgccacctgc gccaccctgc cttcgtgaag aagcagcaca acggggtgtg tgacatggac     1140

tgcaactatg aacggttcaa ctttgatggt ggagagtgct gtgaccctga aatcaccaat     1200

gtcactcaga cttgctttga ccccgactct ccacacagag cctacttgga tgttaatgag     1260

ctgaagaaca ttcttaaatt ggatggatca acacatctca atattttctt tgcaaaatcc     1320

tcagaggagg agttggcagg agtagcaact tggccatggg acaaggaggc cctgatgcac     1380

ttaggtggca ttgtcttgaa cccatctttc tatggcatgc ctgggcacac ccacaccatg     1440

atccatgaga ttggtcacag cctgggcctc tatcacgtct tccgaggcat ctcagaaatc     1500

cagtcctgca gtgacccctg catggagaca gagccctcct tcgagactgg agacctctgc     1560

aatgatacca acccagcccc taaacacaag tcctgtggtg acccagggcc aggaaatgac     1620

acctgtggct ttcatagctt cttcaacact ccttacaaca acttcatgag ctatgcagat     1680

gacgactgta cggactcctt cacgcccaat caagtcgcca gaatgcactg ttacctggac     1740

ctggtctacc agggctggca gccctccagg aaaccagcgc ctgttgccct cgccccccaa     1800

gttctgggcc acacaacgga ctctgtgaca ctggagtggt tcccacctat agatggccat     1860

ttctttgaaa gagaattggg atcagcatgt catctttgcc tggaagggag aatcctggtg     1920

cagtatgctt ccaacgcttc ctccccaatg ccctgcagcc catcaggaca ctggagccct     1980

cgtgaagcag aaggtcatcc tgatgttgaa cagccctgta agtccagtgt ccgcacctgg     2040

agcccaaatt cagctgtcaa cccacacacg gttcctccag cctgccctga gcctcaaggc     2100

tgctacctcg agctggagtt cctctacccc ttggtccctg agtctctgac catttgggtg     2160

acctttgtct ccactgactg ggactctagt ggagctgtca atgacatcaa actgttggct     2220

gtcagtggga agaacatctc cctgggtcct cagaatgtct tctgtgatgt cccactgacc     2280

atcagactct gggacgtggg cgaggaggtg tatggcatcc aaatctacac gctggatgag     2340

cacctggaga tcgatgctgc catgttgacc tccactgcag acaccccact ctgtctacag     2400

tgtaagcccc tgaagtataa ggtggtccgg gaccctcctc tccagatgga tgtggcctcc     2460

atcctacatc tcaataggaa attcgtagac atggatctaa atcttggcag tgtgtaccag     2520

tattgggtca taactatttc aggaactgaa gagagtgagc catcacctgc tgtcacatac     2580

atccatggaa gtgggtactg tggcgatggc attatacaaa aagaccaagg tgaacaatgc     2640

gacgacatga ataagatcaa tggtgatggc tgctcccttt tctgccgaca agaagtctcc     2700

ttcaattgta ttgatgaacc cagccggtgc tatttccatg atggtgatgg ggtatgtgag     2760

gagtttgaac aaaaaaccag cattaaggac tgtggtgtct acacgcccca gggattcctg     2820

gatcagtggg catccaatgc ttcagtatct catcaagacc agcaatgccc aggctgggtc     2880

atcatcggac agccagcagc atcccaggtg tgtcgaacca aggtgataga tctcagtgaa     2940

ggcatttccc agcatgcctg gtacccttgc accatcagct acccatattc ccagctggct     3000

cagaccactt tttggctccg ggcgtatttt tctcaaccaa tggttgccgc agctgtcatt     3060

gtccacctgg tgacggatgg gacatattat ggggaccaaa agcaggagac catcagcgtg     3120

cagctgcttg ataccaaaga tcagagccac gatctaggcc tccatgtcct gagctgcagg     3180

aacaatcccc tgattatccc tgtggtccat gacctcagcc agcccttcta ccacagccag     3240

gcggtacgtg tgagcttcag ttcgcccctg gtcgccatct cgggggtggc cctccgttcc     3300

ttcgacaact ttgaccccgt caccctgagc agctgccaga gaggggagac ctacagccct     3360

gccgagcaga gctgcgtgca cttcgcatgt gagaaaactg actgtccaga gctggctgtg     3420

gagaatgctt atctcaattg ctccagcagc gaccgctacc acggtgccca gtgtactgtg     3480

agctgccgga caggctacgt gctccagata cggcgggatg atgagctgat caagagccag     3540

acgggaccca gcgtcacagt gacctgtaca gagggcaagt ggaataagca ggtggcctgt     3600

gagccagtcg actgcagcat cccagatcac catcaagtct atgctgcctc cttctcctgc     3660

cctgagggca ccacctttgg cagtcaatgt tccttccagt gccgtcaccc tgcacaattg     3720

aaaggcaaca acagcctcct gacctgcatg gaggatgggc tgtggtcctt cccagaggcc     3780

ctgtgtgagc tcatgtgcct cgctccaccc cctgtgccca atgcagacct ccagaccgcc     3840

cggtgccgag agaataagca caaggtgggc tccttctgca aatacaaatg caagcctgga     3900

taccatgtgc ctggatcctc tcggaagtca aagaaacggg ccttcaagac tcagtgtacc     3960

caggatggca gctggcagga gggagcttgt gttcctgtga cctgtgaccc acctccacca     4020

aaattccatg ggctctacca gtgtactaat ggcttccagt tcaacagtga gtgtaggatc     4080

aagtgtgaag acagtgatgc ctcccaggga cttgggagca atgtcattca ttgccggaaa     4140

gatggcacct ggaacggctc cttccatgtc tgccaggaga tgcaaggcca gtgctcggtt     4200

ccaaacgagc tcaacagcaa cctcaaactg cagtgccctg atggctatgc catagggtcg     4260

gagtgtgcca cctcgtgcct ggaccacaac agcgagtcca tcatcctgcc aatgaacgtg     4320

accgtgcgtg acatccccca ctggctgaac cccacacggg tagagagagt tgtctgcact     4380

gctggtctca agtggtatcc tcaccctgct ctgattcact gtgtcaaagg ctgtgagccc     4440

ttcatgggag acaattattg tgatgccatc aacaaccgag ccttttgcaa ctatgacggt     4500

ggggattgct gcacctccac agtgaagacc aaaaaggtca ccccattccc tatgtcctgt     4560

gacctacaag gtgactgtgc ttgtcgggac ccccaggccc aagaacacag ccggaaagac     4620

ctccagggat acagccatgg c                                               4641


<210>  4135
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  4135
tcactttcaa tgagaaatga tgcagtcaat gaaatagttg ctgtgaaaaa caattttcct       60

gtgatagaaa ttgttcagtg taggatgtgc cacctccagt tcccaggaga aaagtgctcc      120

agaggaagag gaatatgcac agcaacaaca gaagaggcct gcatggttgg aaggatgttc      180

aaaagggatg gtaatccctg gttaaccttc atgggctgcc taaagaactg tgctgatgtg      240

aaaggcataa ggtggagtgt ctatttggtg aacttcaggt gctgcaggag ccatgacctg      300

tgcaatgaag acctt                                                       315


<210>  4136
<211>  261
<212>  DNA
<213>  Homo Sapiens

<400>  4136
actgaaataa tgtgttatga atgtaaaaaa tatcatcttg ggttatgcta tggtgtcatg       60

acatcctgct ccctgaagca taaacagtcc tgtgcagttg agaactttta catccttaca      120

aggaaagggc agagcatgta tcattattca aaactgtcgt gtatgaccag ctgtgaggac      180

atcaacttcc tggggttcac gaagagggta gagctcatct gttgtgatca tagtaactac      240

tgcaacctcc ctgagggagt t                                                261


<210>  4137
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  4137
ctacaatgta taacttgtca ccttaggacc agaacggacc gttgtaggag gggctttgga       60

gtatgtacag cccagaaagg cgaggcctgc atgctgttaa gaatatatca acgtaacaca      120

ttgcaaatat cctacatggt ttgtcagaag ttctgccgtg acatgacttt cgaccttcgt      180

aaccgtactt acgttcatac gtgctgtaac tataactact gcaattttaa gctg            234


<210>  4138
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  4138
ttgaaatgta atacgtgtat ttacacagaa gggtggaagt gcatggcagg cagaggcaca       60

tgtatagcca aagaaaatga actatgcagc acaaccgcct actttcgtgg tgataagcac      120

atgtatagca cgcatatgtg caaatacaag tgcagagaag aggagagttc caaacgtgga      180

ttgcttcgtg tcactctatg ctgcgacagg aatttttgta acgtattc                   228


<210>  4139
<211>  2091
<212>  DNA
<213>  Homo Sapiens

<400>  4139
cagcttcact acacggtaca ggaggagcag gaacatggca ctttcgtggg gaatatcgct       60

gaagatctgg gtctggacat tacaaaactt tcggctcgcg ggtttcagac ggtgcccaac      120

tcaaggaccc cttacttaga cctcaacctg gagacagggg tgctgtacgt gaacgagaaa      180

atagaccgcg aacaaatctg caaacagagc ccctcctgtg tcctgcacct ggaggtcttt      240

ctggagaacc ccctggagct gttccaggtg gagatcgagg tgctggacat taatgacaac      300

cccccctctt tcccggagcc agacctgacg gtggaaatct ctgagagcgc cacgccaggc      360

actcgcttcc ccttggagag cgcattcgac ccagacgtgg gcaccaactc cttgcgcgac      420

tacgagatca cccccaacag ctacttctcc ctggacgtgc agacccaggg ggatggcaac      480

cgattcgctg agctggtgct ggagaagcca ctggaccgag agcagcaagc ggtgcaccgc      540

tacgtgctga ccgcggtgga cggaggaggt gggggaggag taggagaagg agggggaggt      600

ggcgggggag caggcctgcc cccccagcag cagcgcaccg gcacggccct actcaccatc      660

cgagtgctgg actccaatga caatgtgccc gctttcgacc aacccgtcta cactgtgtcc      720

ctaccagaga actctccccc aggcactctc gtgatccagc tcaacgccac cgacccggac      780

gagggccaga acggtgaggt cgtgtactcc ttcagcagcc acatttcgcc ccgggcgcgg      840

gagcttttcg gactctcgcc gcgcactggc agactggagg taagcggcga gttggactat      900

gaagagagcc cagtgtacca agtgtacgtg caagccaagg acctgggccc caacgccgtg      960

cctgcgcact gcaaggtgct agtgcgagta ctggatgcta atgacaacgc gccagagatc     1020

agcttcagca ccgtgaagga agcggtgagt gagggcgcgg cgcccggcac tgtggtggcc     1080

cttttcagcg tgactgaccg cgactcagag gagaatgggc aggtgcagtg cgagctactg     1140

ggagacgtgc ctttccgccc caagtcttcc tttaagaatt actacaccat cgttaccgaa     1200

gcccccctgg accgagaggc gggggactcc tacaccctga ctgtagtggc tcgggaccgg     1260

ggcgagcctg cgctctccac cagtaagtcg atccaggtac aagtgtcgga tgtgaacgac     1320

aacgcgccgc gtttcagcca gccggtctac gacgtgtatg tgactgaaaa caacgtgcct     1380

ggcgcctaca tctacgcggt gagcgccacc gaccgggatg agggcgccaa cgcccagctt     1440

gcctactcta tcctcgagtg ccagatccag ggcatgagcg tcttcaccta cgtttctatc     1500

aactctgaga acggctactt gtacgccctg cgctccttcg actatgagca gctgaaggac     1560

ttcagttttc aggtggaagc ccgggacgct ggcagccccc aggcgctggc tggtaacgcc     1620

actgtcaaca tcctcatagt ggatcaaaat gacaacgccc ctgccatcgt ggcgcctcta     1680

ccagggcgca acgggactcc agcgcgtgag gtgctgcccc gctcggcgga gccgggttac     1740

ctgctcaccc gcgtggccgc cgtggacgcg gacgacggcg agaacgcccg gctcacttac     1800

agcatcgtgc gtggcaacga aatgaacctc tttcgcatgg actggcgcac cggggagctg     1860

cgcacagcac gccgagtccc ggccaagcgc gacccccagc ggccttatga gctggtgatc     1920

gaggtgcgcg accatgggca gccgcccctt tcctccaccg ccaccctggt ggttcagctg     1980

gtggatggcg ccgtggagcc ccagggcggg ggcgggagcg gaggcggagg gtcaggagag     2040

caccagcgcc ccagtcgctc tggcggcggg gaaacctcgc tagacctcac c              2091


<210>  4140
<211>  2082
<212>  DNA
<213>  Homo Sapiens

<400>  4140
caggaggtga ccactctcac ggtgaaatac caagtgtcag aggaagtgcc atctggtaca       60

gtgatcggga agctgtccca ggaactgggc cgggaggaga ggcggaggca agctggggcc      120

gccttccagg tgttgcagct gcctcaggcg ctccccattc aggtggactc tgaggaaggc      180

ttgctcagca caggcaggcg gctggatcga gagcagctat gccgacagtg ggatccctgc      240

ctggtttcct ttgatgtgct tgccacaggg gatttggctc tgatccatgt ggagatccaa      300

gtgctggaca tcaatgacca ccagccacgg tttcccaaag gcgagcagga gctggaaatc      360

tctgagagcg cctctctgcg aacccggatc cccctggaca gagctcttga cccagacaca      420

ggccctaaca ccctgcacac ctacactctg tctcccagtg agcactttgc cttggatgtc      480

attgtgggcc ctgatgagac caaacatgca gaactcatag tggtgaagga gctggacagg      540

gaaatccatt cattttttga tctggtgtta actgcctatg acaatgggaa cccccccaag      600

tcaggtacca gcttggtcaa ggtcaacgtc ttggactcca atgacaatag ccctgcgttt      660

gctgagagtt cactggcact ggaaatccaa gaagatgctg cacctggtac gcttctcata      720

aaactgaccg ccacagaccc tgaccaaggc cccaatgggg aggtggagtt cttcctcagt      780

aagcacatgc ctccagaggt gctggacacc ttcagtattg atgccaagac aggccaggtc      840

attctgcgtc gacctctaga ctatgaaaag aaccctgcct acgaggtgga tgttcaggca      900

agggacctgg gtcccaatcc tatcccagcc cattgcaaag ttctcatcaa ggttctggat      960

gtcaatgaca acatcccaag catccacgtc acatgggcct cccagccatc actggtgtca     1020

gaagctcttc ccaaggacag ttttattgct cttgtcatgg cagatgactt ggattcagga     1080

aacaatggtt tggtccactg ctggctgagc caagagctgg gccacttcag gctgaaaaga     1140

actaatggca acacatacat gttgctaacc aatgccacac tggacagaga gcagtggccc     1200

aaatataccc tcactctgtt agcccaagac caaggactcc agcccttatc agccaagaaa     1260

cagctcagca ttcagatcag tgacatcaac gacaatgcac ctgtgtttga gaaaagcagg     1320

tatgaagtct ccacgcggga aaacaactta ccctctcttc acctcattac catcaaggct     1380

catgatgcag acttgggcat taatggaaaa gtctcatacc gcatccagga ctccccagtt     1440

gctcacttag tagctattga ctccaacaca ggagaggtca ctgctcagag gtcactgaac     1500

tatgaagaga tggccggctt tgagttccag gtgatcgcag aggacagcgg gcaacccatg     1560

cttgcatcca gtgtctctgt gtgggtcagc ctcttggatg ccaatgataa tgccccagag     1620

gtggtccagc ctgtgctcag cgatggaaaa gccagcctct ccgtgcttgt gaatgcctcc     1680

acaggccacc tgctggtgcc catcgagact cccaatggct tgggcccagc gggcactgac     1740

acacctccac tggccactca cagctcccgg ccattccttt tgacaaccat tgtggcaaga     1800

gatgcagact cgggggcaaa tggagagccc ctctacagca tccgcagtgg aaatgaagcc     1860

cacctcttca tcctcaaccc tcatacgggg cagctgttcg tcaatgtcac caatgccagc     1920

agcctcattg ggagtgagtg ggagctggag atagtagtag aggaccaggg aagccccccc     1980

ttacagaccc gagccctgtt gagggtcatg tttgtcacca gtgtggacca cctgagggac     2040

tcagcccgca agcctggggc tttgagcatg tcgatgctga cg                        2082


<210>  4141
<211>  2490
<212>  DNA
<213>  Homo Sapiens

<400>  4141
agttacagcc gggccaccga gcttctgtac agcctaaacg agggactacc cgcgggggtg       60

ctcatcggca gcctggccga ggacctgcgg ctgctgccca ggtctgcagg gaggccggac      120

ccgcagtcgc agctgccaga gcgcaccggt gctgagtgga acccccctct ctccttcagc      180

ctggcctccc ggggactgag tggccagtac gtgaccctag acaaccgctc tggggagctg      240

cacacttcag ctcaggagat cgacagggag gccctgtgtg ttgaaggggg tggagggact      300

gcgtggagcg gcagcgtttc catctcctcc tctccttctg actcttgtct tttgctgctg      360

gatgtgcttg tcctgcctca ggaatacttc aggtttgtga aggtgaagat cgccatcaga      420

gacatcaatg acaacgcccc gcagttccct gtttcccaga tctcggtgtg ggtcccggaa      480

aatgcacctg taaacacccg actggccata gagcatcctg ctgtggaccc agatgtaggc      540

attaatgggg tacagaccta tcgcttactg gactaccatg gtatgttcac cctggacgtg      600

gaggagaatg agaatgggga gcgcaccccc tacctaattg tcatgggtgc tttggacagg      660

gaaacccagg accagtatgt gagcatcatc atagctgagg atggtgggtc tccaccactt      720

ttgggcagtg ccactctcac cattggcatc agtgacatta atgacaattg ccctctcttc      780

acagactcac aaatcaatgt cactgtgtat gggaatgcta cagtgggcac cccaattgca      840

gctgtccagg ctgtggataa agacttgggg accaatgctc aaattactta ttcttacagt      900

cagaaagttc cacaagcatc taaggattta tttcacctgg atgaaaacac tggagtcatt      960

aaacttttca gtaagattgg aggaagtgtt ctggagtccc acaagctcac catccttgct     1020

aatggaccag gctgcatccc tgctgtaatc actgctcttg tgtccattat taaagttatt     1080

ttcagacccc ctgaaattgt ccctcgttac atagcaaacg agatagatgg tgttgtttat     1140

ctgaaagaac tggaacccgt taacactccc attgcgtttt tcaccataag agatccagaa     1200

ggtaaataca aggttaactg ctacctggat ggtgaagggc cgtttaggtt atcaccttac     1260

aaaccataca ataatgaata tttactagag accacaaaac ctatggacta tgagctacag     1320

cagttctatg aagtagctgt ggtggcttgg aactctgagg gatttcatgt caaaagggtc     1380

attaaagtgc aacttttaga tgacaatgat aatgctccaa ttttccttca acccttaata     1440

gaactaacca tcgaagagaa caactcaccc aatgcctttt tgactaagct gtatgctaca     1500

gatgccgaca gcgaggagag aggccaagtt tcatattttc tgggacctga tgctccatca     1560

tatttttcct tagacagtgt cacaggaatt ctgacagttt ctactcagct ggaccgagaa     1620

gagaaagaaa agtacagata cactgtcaga gctgttgact gtgggaagcc acccagagaa     1680

tcagtagcca ctgtggccct cacagtgttg gataaaaatg acaacagtcc tcggtttatc     1740

aacaaggact tcagcttttt tgtgcctgaa aactttccag gctatggtga gattggagta     1800

attagtgtaa cagatgctga cgctggacga aatggatggg tcgccctctc tgtggtgaac     1860

cagagtgata tttttgtcat agatacagga aagggtatgc tgagggctaa agtctctttg     1920

gacagagagc agcaaagctc ctatactttg tgggttgaag ctgttgatgg gggtgagcct     1980

gccctctcct ctacagcaaa aatcacaatt ctccttctag atatcaatga caaccctcct     2040

cttgttttgt ttcctcagtc taatatgtct tatctgttag tactgccttc tactctgcca     2100

ggctccccgg ttacagaagt ctatgctgtc gacaaagaca caggcatgaa tgctgtcata     2160

gcttacagca tcatagggag aagaggtcct aggcctgagt ccttcaggat tgaccctaaa     2220

actggcaaca ttactttgga agaggcattg ctgcagacag attatgggct ccatcgctta     2280

ctggtgaaag tgagtgatca tggttatccc gagcctctcc actccacagt catggtgaac     2340

ctatttgtca atgacactgt cagtaatgag agttacattg agagtctttt aagaaaagaa     2400

ccagagatta atatagagga gaaagaacca caaatctcaa tagaaccgac tcataggaag     2460

gtagaatctg tgtcttgtat gcccacctta                                      2490


<210>  4142
<211>  2373
<212>  DNA
<213>  Homo Sapiens

<400>  4142
caagaactta tttacactat tagagaggaa ttgcctgaaa atgtgcccat aggaaacata       60

ccaaaggatc tgaacatttc tcacatcaat gctgccacag ggaccagcgc cagccttgtc      120

tacagactgg tttctaaagc tggggatgcc cctttggtga aagtatccag cagcactggg      180

gaaattttca caacctccaa cagaatagac agagaaaaac tctgtgctgg cgcctcatat      240

gctgaggaga atgagtgttt ctttgaactt gaggtggtga tcctccccaa tgatttcttc      300

aggctgatca aaataaaaat aattgtcaag gataccaatg ataatgcccc catgtttcca      360

tctcctgtca tcaatatttc cattccagaa aacactttga tcaacagccg ctttccaatt      420

ccatcagcaa cagatcctga cacaggcttc aatggtgtac agcattatga attgttaaat      480

gggcagagtg tttttggact ggatatcgtg gaaactccag agggagagaa gtggccacaa      540

ctgattgttc agcaaaactt ggatagagaa cagaaagata cctatgtgat gaaaatcaaa      600

gtagaggatg gaggcactcc acagaaatcc agtacggcca tactgcaggt cacagtaagt      660

gatgtaaatg acaacaggcc agtgtttaaa gagggtcaag tggaggtgca tattccagag      720

aatgctcccg taggtacctc tgtaattcag ctccatgcca ctgatgcaga tataggcagt      780

aatgctgaaa tccggtacat ttttggtgcc caggtcgccc ctgcaaccaa aagactcttt      840

gctttaaata atactactgg gctgattaca gttcagaggt ccttagatag agaggagaca      900

gccattcaca aagtgacagt gctggctagt gacggcagct ccactcctgc tcgagcaacg      960

gttaccatca atgtcaccga tgtaaatgat aaccctccta atatagacct caggtacatt     1020

ataagtccca tcaatggcac cgtgtattta tctgagaaag atcctgtcaa tacaaagatt     1080

gccctaatta cagtttcaga taaggacaca gatgtgaatg gcaaagtgat ctgttttatt     1140

gaaagagagg tcccatttca tttgaaggcg gtatatgaca accaatattt gttagagacc     1200

tcttctttgt tggactatga gggcaccaaa gaattcagct ttaaaattgt tgcctctgat     1260

tctgggaagc ccagtttaaa tcagactgcc ctggtaaggg ttaagcttga ggatgaaaat     1320

gacaacccac caattttcaa ccagcctgta attgagctgt cagtttctga aaacaaccga     1380

cgtgggttat acttaacaac tattagtgcc acagatgaag acagtgggaa aaatgcagac     1440

attgtttatc agcttggacc taatgcctcc ttctttgatc tggaccgaaa aacaggagtt     1500

ttgacagcct ccagagtatt tgacagagaa gaacaagaac gattcatttt tacagtaact     1560

gccagggata atgggacccc tcccctccaa agccaagcgg ctgtgattgt tactgttctg     1620

gatgagaatg acaatagccc caagtttact cataatcatt ttcaattttt tgtgtctgag     1680

aatctgccaa agtatagtac tgtgggggta atcacagtga cagatgcaga tgctggagag     1740

aataaagctg tgactctttc cattctaaat gacaatgata attttgtgtt ggatccctat     1800

tctggagtca taaagtcaaa tgtctcattt gatagagagc agcagagttc ctacactttt     1860

gatgtcaaag ccactgatgg aggacaacca cctcgttcct ctactgcaaa agtaactatc     1920

aacgtcatgg atgtcaatga caacagccca gttgtcattt ctccaccgtc taatacttcc     1980

tttaagttgg tgcccctctc agccattcct ggctccgtgg tagcagaagt ttttgcagtg     2040

gatgttgaca ctggaatgaa cgctgaacta aagtatacta tagtgagtgg aaacaataaa     2100

ggcttattcc ggattgatcc agtaacaggt aacattactc tggaagaaaa accagcacct     2160

actgatgtgg gattgcatcg tttggtggtc aacataagtg acctggggta ccctaagtct     2220

ttgcacacgc ttgtgcttgt attcctttat gttaacgaca ctgctggaaa tgcctcctat     2280

atctatgact tgatccgcag gactatggag accccgttgg acaggaacat aggggatagt     2340

agccaaccct atcaaaatga ggactatcta acc                                  2373


<210>  4143
<211>  2004
<212>  DNA
<213>  Homo Sapiens

<400>  4143
cagctccact actccgtccc ggaggaagcc gaacacggca ccttcgtggg ccgcatcgcg       60

caggacctgg ggctggagct ggcggagctg gtgccgcgcc tgttccagtt ggattccaaa      120

ggccgcgggg accttctgga ggtaaatctg cagaatggca ttttgtttgt gaattctcgg      180

atcgaccgcg aggagctgtg cgggcggagc gcggagtgca gcatccacct ggaggtgatc      240

gtagacaggc cgctgcaggt tttccatgtg gacgtggagg tgaaggacat taacgacaac      300

cctccagtgt tcccagcgac acaaaagaat ctgttcatcg cggaatccag gccgcttgac      360

tctcggtttc cactagaggg cgcgtccgat gcagatatcg gggagaacgc cctgctcact      420

tacagactga gccccaatga gtatttcttc ctggacgtgc caaccagcaa ccagcaggta      480

aaacctcttg gacttgtatt acggaaactt ttagacagag aagaaactcc ggagcttcat      540

ttattgctca cggccaccga tggaggcaaa cccgagctga ctggcaccgt tcaattactc      600

atcacggtac tggacaacaa tgacaatgcc ccagtgttcg acagaaccct gtatacggtg      660

aaattaccag aaaacgtttc tatcggaacg ctggtgattc accccaatgc ctcagattta      720

gacgaaggct tgaatgggga tattatttac tccttctcca gtgatgtttc tccagatata      780

aaatccaagt tccacatgga ccccttaagt ggggcaatca cagtgatagg acatatggat      840

tttgaagaaa gtagagcaca caagatccca gtcgaggctg tcgataaagg cttcccaccc      900

ctggctggtc attgtacact tcttgtggaa gttgtggatg taaatgacaa tgctccacag      960

ttgactatca aaacgctctc ggttcctgta aaagaggacg cacaactggg gacagttatt     1020

gccctgatta gtgtgatcga cctagacgca gatgccaacg ggcaggttac ctgctccctg     1080

acgccccacg tccccttcaa gctggtgtcc acctacaaga attactactc gttggtgctg     1140

gacagagctc tggaccgcga gagtgtgtcc gcctacgagc tggtggttac cgcgcgggac     1200

gggggctcgc cttcactgtg ggccacggcc agggtgtctg tggaggtggc cgacgtgaac     1260

gacaacgcac cagcgttcgc gcagtccgag tacacggtgt tcgtgaagga gaacaacccg     1320

ccgggctgcc acatcttcac ggtgtctgcg cgggacgctg acgcgcagga gaacgccctg     1380

gtgtcctact cgctggtgga gcggcggttg ggcgagcgct cgctgtcgag ctacgtgtca     1440

gtgcacgcgg agagcggcaa ggtgtacgcg ctgcagccgt tggaccacga ggagctggag     1500

ctgctacagt tccaggtgag cgcgcgcgac gcgggcgtgc cgcctctggg cagcaacgtg     1560

acgctgcagg tgttcgtgct ggacgagaac gacaatgcgc cggcgctgct gacacctcgg     1620

atgaggggca ctgacggcgc agtgagcgag atggtgctgc ggtcggtggg cgccggcgta     1680

gtggtgggga aggtgcgcgc agtggacgcc gactcgggct acaacgcgtg gctttcatac     1740

gagctgcagc cagaaacggc cagcgcgagc atcccgttcc gcgtggggct gtacacgggc     1800

gagatcagca caacgcgtgc cctggacgaa acggacgcac cgcgccagcg cctactggtg     1860

ctggtgaaag accacgggga gccagcgctg acggccacgg ccactgtgct ggtgtcgctg     1920

gtggagagcg gccaggcgcc aaagtcatcg tcgcgggcgt cagtgggtgc cacgggcccc     1980

gaggtgacgc tggtggatgt caac                                            2004


<210>  4144
<211>  1989
<212>  DNA
<213>  Homo Sapiens

<400>  4144
acaactatcc gctattcagt ggcagaggaa atggagagcg gctcgtttgt ggccaacgta       60

gctaaggacc taggactgga ggtagggaag ctggctgcgc gcggggcgcg gctggtttcc      120

gagggcaaca aaatgcattt ccggctccac cgcaagacgg gagatttgtt tgtgaaggag      180

aaactggatc gggagtcact ttgtggcaaa gccgaccctt gtgttctgca ctttgaagta      240

gtcctggtgg agccgctgca gtccttccgg gccgaggtca gggtatttga tatcaatgac      300

aatgccccag ttttcctaaa caaggagccg cttttaaaga ttccggagag cacccctttg      360

ggttcacgtt ttcctctgca gagcgcccag gatctggacg tgggccttaa cggtctccag      420

aactacaccc tgagtgccaa tgggtatttc cacctgcaca cccgcttctg cagccacggg      480

cctaaatatg ctgagctggt gctgaacaaa cccctggacc gagaggagca gcctgaagtc      540

aacttgacaa ttacggcggt ggacggcggg tccccgccta agtctggcac agctcacatc      600

cacgtggtgg ttctggatgt caacgaccac gtgccccagt tctcgcgact ggtgtacaga      660

gcccaggtat cagagaacag ccccaatggc tctttggtgg ccacggtgac tgccgtggac      720

ctagacgagg gcaccaacaa agcgataact tactctttag ctcaaaaccc agaagcaatt      780

ctcaagacgt ttcagattga ccctcaaaat ggagaagttc gactaagagg acccctcgat      840

tttgaagcca ttgaaacata cgacattgac attcaagcta cagatggtgg aggcctctct      900

gcccacagca aagtcctggt agaagtggtg gatgtgaatg acaatcctcc cgaagtgatg      960

gtctcctctg tgtccagccc actccctgaa gactcaccac cacagacagt agtagccctt     1020

ttcactatca gagaccggga cattcgagtg ggaggaaaag tcacctgctt cctcagagaa     1080

gaccttccct ttgtaatcaa acctacattt gggaattctt actcactggt cactgacaga     1140

agcttggatc gggaggaggt ctcaggctat aatatcacca ttgttgccat ggatactgga     1200

ccacctagct tgtctgccga gactatgata gaggtgctaa tatccgacgt taatgacaat     1260

cctccaatat ttcgggaaga ttcctatatc ttgactgttc gagaaaacaa cagtcctgcg     1320

gtttttattg gcaaagtcca tgctgaggat cttgatttgg gtgagaatgc ccaaataaca     1380

tattctctgt tgcctccaaa aaacggagat ctttcagtct ttgcttacat atccataaat     1440

tcaggcaatg ggaagctcta cgcgctgaga accatggatt atgaggccat tcaagatttt     1500

caatttgtgg taaaggcaac tgatgggggc ttcctgtcac tgagtagcca agttactgtc     1560

agagtggttg tcctagatga caatgacaat cgtccaatga tcttataccc actgcagaac     1620

ggcaccttgc cctgcaatga cctggtgccc aggtctgcag aggcaggcta cctagtgacc     1680

aaagtggtgg ctgtggatgg tgactcaggt cagaattctt ggctttcata tcatctactt     1740

aaggccactg accttgggtt attttctgtt caaagacaaa atggagaaat ccatacatta     1800

aggcagatat ctgagagaga ccccatgatg cagaaattga tcattcttgt tcaggatcac     1860

ggccaaccag ctctttccac tactgtctca ctcaacatcc tgctggtaga tggcttttca     1920

gagccctacc tgcagttcca ggatccaacc aagcattcta gaaaggtaaa tccatccact     1980

aaatatttg                                                             1989


<210>  4145
<211>  1992
<212>  DNA
<213>  Homo Sapiens

<400>  4145
ggctctgaaa cctggagctt ttctgtggca gaagaaatgc agagcgggag ttttgtaggc       60

aatctggcaa aggacctggg gctgaaggtg agagaactgt cctcacgggg ggctcgggtg      120

gtctctaatg ataagaaaca gcgtttgcag ctggacataa acactgggga tttgctctta      180

agtgaaacac tagacaggga ggagctctgc ggttccatcg agccttgcgt gctacatttg      240

caggtgttaa tgcaaaaccc cacgcagttt ttacaaattg agcttcaggt cagggatata      300

aatgatcact ctcccatctt ctcggaaaaa caaatgctcc tagaaatccc agagaacagt      360

cccgttggtg ctgtgttctt actagaaagt gcgaaggatt tagatgtagg aatcaatgct      420

gtaaaaagct acacaataag ccccaactct cattttcaca ttaaaatgag agtcattcca      480

gacaatagga aataccccga gttagttctg gacaaggcgc tggattatga agagctcccg      540

gagctcagtt tcatcctctc tgctctggat ggtgggtccc ctcccaggtc tggaactgcc      600

ttggtcaggg tggtggttgt ggacattaat gacaactccc ctgaatttga gcaggctttt      660

tatgaggtga agattcggga gaatagcatc cttggctcgc tgattttgat tgtctcagct      720

tgggatttag actctggaac aaatggtgaa atatgctata ccttttccca tgcctcagaa      780

gatattcgca agacatttga aattaatcaa aagtctggag aaattacttt aagagcacct      840

ctggattttg aaacgattga gtcatactca ataatcattc aagccacaga tgggggagga      900

ctttttggaa aatctacagt cataattcac gtgatagatg taaatgacaa tgctcctgaa      960

atcactgtgt catcaattac cagtccaatc ccagaaaata cgccagagac cgtggttatg     1020

gtttttagta tccaagatat agactctggg gacaacggaa gaattgtttg ttccattccg     1080

gaagacctcc cattcgtgct aaaatcttca gttgagaatt actacacgtt ggaaacagag     1140

agaccactgg acagagagag cacagccgag tacaatatca ccatcaccgt caccgacttg     1200

gggataccca ggctgaaaac cgagcacaac acaactgtgt tggtctctga cgtcaatgac     1260

aacgccccca ccttcaccca aacctcctac accctgttcg tccgcgagaa caacagcccc     1320

gccctgcaca tcggcagtgt cagcgctaca gacagagact caggcaccaa cgcccaggtc     1380

aactactcgc tactcccgcc ccaggacctg cacctgcccc tcgcctccct ggtctccatc     1440

aacacagaca acggccacct gttcgccctc aggtcgctgg actacgaggc cctgcaggct     1500

ttcgacttcc gcgtgggcgc cacagaccgc ggctccccgg ctttgagcag cgaggcgctg     1560

gtgcgcgtgc tggtgctgga cgccaacgac aactcgccct tcgtgctgta cccgctgcag     1620

aacggctccg cgccctgcac cgagctggtg ccccgggcgg ccgagccggg ctacctggtg     1680

accaaggtgg tggcggtgga cggcgactcg ggccagaacg cctggctgtc gtaccagctg     1740

ctcaaggcca cggagcccgg gctattcggc gtgtgggcgc acaatggcga ggtgcgcacc     1800

gccaggctgc tgagcgagcg cgacgcggcc aagcacaggc tggtggtgct ggtcaaggac     1860

aatggcgagc ctccgcgctc ggccaccgcc acgctgcaag tgctcctggt ggacggcttc     1920

tcccagccct acctgccgct ccctgaggcg gcaccggccc aggcccaggc cgactcgctc     1980

accgtctact tg                                                         1992


<210>  4146
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  4146
gaacctagaa gctattctgt ggtggaggaa actgagggca gctcctttgt caccaattta       60

gcaaaggacc tgggtctgga gcagagggaa ttctccaggc ggggggttag ggttgtttcc      120

agagggaaca aactacattt gcagctcaat caggagaccg cggatttgtt gctaaatgag      180

aaattggacc gtgaggatct gtgcggtcac acagagccct gtgtgctacg tttccaagtg      240

ttgctagaga gtcccttcga gttttttcaa gctgagctgc aagtaataga cataaacgac      300

cactctccag tatttctgga caaacaaatg ttggtgaaag tatcagagag cagtcctcct      360

gggactacgt ttcctctgaa gaatgccgaa gacttagatg taggccaaaa caatattgag      420

aactatataa tcagccccaa ctcctatttt cgggtcctca cccgcaaacg cagtgatggc      480

aggaaatacc cagagctggt gctggacaaa gcgctggacc gagaggaaga agctgagctc      540

aggttaacac tcacagcact ggatggtggc tctccgccca gatctggcac tgctcaggtc      600

tacatcgaag tcctggatgt caacgataat gcccctgaat ttgagcagcc tttctataga      660

gtgcagatct ctgaggacag tccggtaggc ttcctggttg tgaaggtctc tgccacggat      720

gtagacacag gagtcaacgg agagatttcc tattcacttt tccaagcttc agaagagatt      780

ggcaaaacct ttaagatcaa tcccttgaca ggagaaattg aactaaaaaa acaactcgat      840

ttcgaaaaac ttcagtccta tgaagtcaat attgaggcaa gagatgctgg aaccttttct      900

ggaaaatgca ccgttctgat tcaagtgata gatgtgaacg accatgcccc agaagttacc      960

atgtctgcat ttaccagccc aatacctgag aacgcgcctg aaactgtggt tgcacttttc     1020

agtgtttcag atcttgattc aggagaaaat gggaaaatta gttgctccat tcaggaggat     1080

ctacccttcc tcctgaaatc cgcggaaaac ttttacaccc tactaacgga gagaccacta     1140

gacagagaaa gcagagcgga atacaacatc actatcactg tcactgactt ggggacccct     1200

atgctgataa cacagctcaa tatgaccgtg ctgatcgccg atgtcaatga caacgctccc     1260

gccttcaccc aaacctccta caccctgttc gtccgcgaga acaacagccc cgccctgcac     1320

atccgcagcg tcagcgctac agacagagac tcaggcacca acgcccaggt cacctactcg     1380

ctgctgccgc cccaggaccc gcacctgccc ctcacatccc tggtctccat caacgcggac     1440

aacggccacc tgttcgccct caggtctctg gactacgagg ccctgcaggg gttccagttc     1500

cgcgtgggcg cttcagacca cggctccccg gcgctgagca gcgaggcgct ggtgcgcgtg     1560

gtggtgctgg acgccaacga caactcgccc ttcgtgctgt acccgctgca gaacggctcc     1620

gcgccctgca ccgagctggt gccccgggcg gccgagccgg gctacctggt gaccaaggtg     1680

gtggcggtgg acggcgactc gggccagaac gcctggctgt cgtaccagct gctcaaggcc     1740

acggagctcg gtctgttcgg cgtgtgggcg cacaatggcg aggtgcgcac cgccaggctg     1800

ctgagcgagc gcgacgcggc caagcacagg ctggtggtgc tggtcaagga caatggcgag     1860

cctccgcgct cggccaccgc cacgctgcac gtgctcctgg tggacggctt ctcccagccc     1920

tacctgcctc tcccggaggc ggccccgacc caggcccagg ccgacttgct caccgtctac     1980

ctg                                                                   1983


<210>  4147
<211>  1992
<212>  DNA
<213>  Homo Sapiens

<400>  4147
ggctgggaac cccgtcgcta ttctgtgatg gaggaaacag agagaggttc ttttgtagcc       60

aacctggcca atgacctagg gctgggagtg ggggagctag ccgagcgggg agcccgggta      120

gtttctgagg ataacgaaca aggcttgcag cttgatctgc agaccgggca gttgatatta      180

aatgagaagc tggaccggga gaagctgtgt ggccctactg agccctgtat aatgcatttc      240

caagtgttac tgaaaaaacc tttggaagta tttcgagctg aactactagt gacagacata      300

aacgatcatt ctcctgagtt tcctgaaaga gaaatgaccc tgaaaatccc agaaactagc      360

tcccttggga ctgtgtttcc tctgaaaaaa gctcgggact tggacgtggg cagcaataat      420

gttcaaaact acaatatttc tcccaattct catttccatg tttccactcg cacccgaggg      480

gatggcagga aatacccaga gctggtgctg gacacagaac tggatcgcga ggagcaggcc      540

gagctcagat taaccttgac agcggtggac ggtggctctc caccccgatc tggcaccgtc      600

cagatcctca tcttggtctt ggacgccaat gacaatgccc cggagtttgt gcaggcgctc      660

tacgaggtgc aggtcccaga gaacagccca gtaggctccc tagttgtcaa ggtctctgct      720

agggatttag acactgggac aaatggagag atatcatact ccctttatta cagctctcag      780

gagatagaca aaccttttga gctaagcagc ctttcaggag aaattcgact aattaaaaaa      840

ctagattttg agacaatgtc ttcgtatgat ctagatatag aggcatctga tggcggggga      900

ctttctggaa aatgctctgt ctctgttaag gtgctggatg ttaacgataa cttcccggaa      960

ctaagtattt catcacttac cagccctatt cccgagaatt ctccagagac agaagtggcc     1020

ctgtttagga ttagagaccg agactctggg gaaaatggaa aaatgatttg ctcaattcag     1080

gatgatgttc cttttaagct aaaaccttct gttgagaatt tctacaggct ggtaacagaa     1140

ggggcgctgg acagagagac cagagccgag tacaacatca ccatcaccat cacagacttg     1200

gggactccaa ggctgaaaac cgagcagagc ataaccgtgc tggtgtcgga cgtcaatgac     1260

aacgcccccg ccttcaccca aacctcctac accctgttcg tccgcgagaa caacagcccc     1320

gccctgcaca tcggcagtgt ccgcgcaaca gacagagact cgggcaccaa cgcccaggtc     1380

acctactcgc tgctgccgcc ccaggacccg cacctgcccc tcacctccct ggtctccatt     1440

aacacggaca acggccacct gttcgctctc cagtcgctgg actacgaggc cctgcaggct     1500

ttcgagttcc gcgtgggcgc cacagaccgc ggcttcccgg cgctgagcag cgaggcgctg     1560

gtgcgagtgc tggtgctgga cgccaacgac aactcgccct tcgtgctgta cccgctgcag     1620

aacggctccg cgccctgcac cgagctggtg ccccgggcgg ccgagccggg ctacctggtg     1680

accaaggtgg tggcggtgga cggcgactcg ggccagaacg cctggctgtc gtaccagctg     1740

ctcaaggcca cggagcccgg gctgttcggc gtgtgggcgc acaatggcga ggtgcgcacc     1800

gccaggctgc tgagcgagcg cgacgtggcc aagcacaggc tagtggtgct ggtcaaggac     1860

aatggcgagc ctccgcgctc ggccaccgcc acgctgcaag tgctcctggt ggacggcttc     1920

tctcagccct acctgccgct cccagaggcg gccccggccc aagcccaggc cgactcgctt     1980

accgtctacc tg                                                         1992


<210>  4148
<211>  1986
<212>  DNA
<213>  Homo Sapiens

<400>  4148
gagttggggt cctattccgt agtggaagaa acggagagag gctcttttgt ggcaaatcta       60

ggaaaagacc tggggttggg gttgacagag atgtccaccc gcaaggccag gatcatttcc      120

caggggaaca aacagcattt gcagctcaag gctcaaactg gggatttgct cataaatgag      180

aagctagatc gagaggagct atgcggtccc actgagcctt gcatactaca tttccaagtg      240

ttaatggaaa accctttaga aatatttcag gctgaactga gggtgataga tataaatgac      300

cattctccca tgttcactga aaaggaaatg attctaaaaa taccggaaaa cagtcctcta      360

ggaactgagt tccctctgaa tcatgctttg gacttggacg taggaagcaa taatgttcaa      420

aactataaaa tcagcccaag ctctcatttc cgggttctaa tccatgaatt cagagatggc      480

aggaaatacc ctgagctagt gttggataaa gagctggatc gggaggagga gcctcaacta      540

agattaaccc tgacagcgct ggatggtggc tctccaccgc gatctggaac tgctcaggtc      600

cgtattgaag tggtggacat caatgataac gctcctgagt ttgagcagcc catctacaaa      660

gtgcagattc cagagaacag tcctcttggc tccctggttg ccaccgtctc cgccagggat      720

ttagacggcg gagccaatgg aaaaatatca tacacactct ttcagccttc ggaggatatt      780

agtaaaactt tggaggtaaa tcctatgaca ggggaagttc gactgagaaa gcaagtagat      840

ttcgaaatgg ttacgtctta tgaagtgcgc atcaaagcca cagatggggg aggtctttca      900

ggaaagtgca ctcttctcct gcaggtggtg gacgtgaatg acaatccccc acaggtgacc      960

atgtctgcac tcaccagccc catcgcagag aactcgcctg agatagtagt tgctgttttc     1020

agcgtttcag atcctgactc cggaaacaat gggaagacga tttcctccat ccaggaagac     1080

cttccctttc ttctaaaacc ttcagtcaag aacttttaca ccttggtaac ggagagagca     1140

ctcgacagag aagcaagagc tgaatataat atcaccctca ccgtcacaga tatggggact     1200

ccaaggctga aaacggagca caacataaca gtgcagatat cagatgtcaa tgataacgcc     1260

cccactttca cccaaacctc ctacaccctg ttcgtccgcg agaacaacag ccccgccctg     1320

cacatcggca gcgtcagcgc cacagacaga gactcgggca ccaacgccca ggtcacctac     1380

tcgctgctgc cgccccaaga cccgcacctg cccctcgcct ccctggtctc catcaacgcg     1440

gacaacggcc acctgttcgc cctcaggtcg ctggactacg aggccctgca ggctttcgag     1500

ttccgcgtgg gcgccacaga ccgcggctcc cccgcgctga gcagagaggc gctggtgcgc     1560

gtgctggtgc tggacgccaa cgacaactcg cccttagtgc tgtacccgct gcagaacggc     1620

tccgcgccct gcactgagct ggtgccccgg gcggccgagc cgggctacct ggtgaccaag     1680

gtggtggcgg tggacggcga ctcgggccag aatgcctggc tgtcgtacca gctgctcaag     1740

gccacggagc ccgggctgtt cggtgtgtgg gcgcacaatg gcgaggtgcg caccgccagg     1800

ctgctgagcg agcgcgacgc agccaagcag aggctggtgg tgctggtcaa ggacaatggc     1860

gagcctccgc gctcggccac cgccacgctg cacgtgctcc tggtggacgg cttctcccag     1920

cccttcctgc cgctcccaga ggcggccccc ggccagaccc aggccaactc gctcactgtc     1980

tacctg                                                                1986


<210>  4149
<211>  1992
<212>  DNA
<213>  Homo Sapiens

<400>  4149
gggtccgagt caagacgcta ttctgtggct gaggaaaaag agaggggctt tttaatagcc       60

aacctagcaa aggatctggg actaagggta gaggaactgg ccgcgagggg ggcccaagtt      120

gtgtccaaag ggaacaaaca gcattttcag ctcagtcatc agacaggtga tttgctcctg      180

aatgagaaat tggaccggga ggagctatgc ggccccacag aaccatgcat actacatttt      240

cagatattac tgcaaaaccc tttgcagttc gttacaaacg agctccgtat catagatgta      300

aatgaccatt ctccggtatt ctttgaaaat gaaatgcatc tgaaaatcct agaaagcact      360

ctgccaggaa cagtaattcc tttgggaaat gctgaggact tggatgtggg aagaaacagc      420

ctccaaaact acactatcac tccgaattcc cacttccacg tactcactcg cagtcgtagg      480

gacggaagga agtacccgga actagtactg gataaagcgc tcgatcggga ggagcagccg      540

gaactcagct taacgctcac cgcgctggac ggcggctctc cccctcggtc tgggacagcc      600

cagataaaca tccaggtctt agatataaac gacaatgcac cagaatttgc acagccgctc      660

tatgaggttg cagttctaga gaataccccc gttaactctg tcattgtcac tgtctcggct      720

tctgacttag atacaggaag ttttgggaca atatcatatg cattttttca tgcttctgaa      780

gaaattcgca aaacttttca gctaaatcca attactggtg atatgcaact ggtcaaatat      840

ttgaattttg aagcgattaa tagttatgaa gtcgacatcg aggccaagga tggcggaggc      900

ctatccggaa agtctacagt catagtccag gtggttgatg tcaacgacaa cccaccggaa      960

ctgaccttgt cttcagtaaa cagccctatt cctgagaact cgggagagac tgtactggct     1020

gttttcagtg tttctgatct agactctgga gacaacggaa gagtgatgtg ttccattgag     1080

aacaatctcc ccttcttcct gaaaccatct gtagagaatt tttacaccct agtgtcagaa     1140

ggcgcgctgg acagagagac cagatccgag tacaacatta ccatcactat cactgacctg     1200

gggacaccca ggctgaaaac caagtacaac ataaccgtgc tggtctccga cgtcaatgac     1260

aacgcccccg ccttcaccca aacctcctac accctgttcg tccgcgagaa caacagcccc     1320

gccctgcaca tcggcagtgt cagcgccaca gacagagact caggcaccaa cgcccaggta     1380

acctactcgc tgctgccgcc ccaggacccg cacctgcccc tctcttccct ggtctccatc     1440

aacgcggaca acggccacct gtttgccctc aggtcgctgg actacgaggc cctgcaggcg     1500

ttcgagttcc gcgtgggcgc cgcagaccgc ggctccccgg ctttgagcag cgaggcgctg     1560

gtgcgcgtgc tggtgctgga cgccaacgac aactcgccct ttgtgctgta cccgctgcag     1620

aacggctccg cgccctgcac cgagctggtg ccccgggcgg ctgagccggg ctacctggtg     1680

accaaggtgg tggcggtgga cagcgactcg ggccagaacg cctggctgtc gtaccagctg     1740

ctcaaggcca cggagcccgg gctgttcggc gtgtgggcgc acaatggcga ggtgcgcacc     1800

gccaggctgc tgagcgagcg cgacgcggcc aagcacaggc tggtggtgct ggtcaaggac     1860

aatggcgagc ctccgcgctc ggccaccgcc acgctgcatg tgctcctggt ggacggcttc     1920

tcccagccct acctgcctct cccggaggcg gcaccggccc aggcccaggc cgacttgctc     1980

accgtctacc tg                                                         1992


<210>  4150
<211>  1977
<212>  DNA
<213>  Homo Sapiens

<400>  4150
gttaggtatt ccataccaga agaaacagaa agtggctatt ctgtggccaa cctggcaaaa       60

gacctgggtc ttggggtggg ggaactggcc actcggggcg cgcgaatgca ttacaaagga      120

aacaaagagc tcttgcagct tgatataaag accggcaatt tgcttctata tgaaaaacta      180

gaccgggagg tgatgtgcgg ggcgacagaa ccctgtatat tgcatttcca gctcttacta      240

gaaaatccag tgcagttttt tcaaactgat ctgcagctca cagatataaa tgaccatgcc      300

ccagagttcc cagagaagga aatgctccta aaaatcccag agagcaccca gccagggact      360

gtgtttccct taaaaatagc ccaggacttt gacataggta gcaacactgt tcagaactac      420

acaatcagcc caaattcaca ctttcatgtt gctacgcata atcgcggaga tggcagaaaa      480

tacccagagc tggtgctgga caaagcgctg gaccgggagg agcggcctga gctcagctta      540

acactcactg cactggacgg tggggctccg cccaggtccg ggaccaccac aattcgcatt      600

gtcgtcttgg ataataatga caacgccccc gaatttttac aatcattcta tgaggtacag      660

gtgcccgaga acagccccct taactcctta gttgtcgttg tctccgctcg agatttagat      720

gcaggagcat atgggagtgt agcctatgct ctattccaag gcgatgaagt tactcaacca      780

tttgtaatag acgagaaaac agcagaaatt cgcctgaaaa gggcattgga tttcgaggca      840

actccatatt ataacgtgga aattgtagcc acagatggtg ggggcctttc aggaaaatgc      900

actgtggcta tagaagtggt ggatgtgaat gacaacgccc ctgaactcac catgtctacg      960

ctctccagcc ctaccccaga aaatgccccg gaaactgtag ttgccgtttt cagtgtttct     1020

gatccagact ccggggacaa cggtaggatg atttgctcca tccagaatga tctccccttt     1080

cttttgaagc ccacattaaa aaacttttac accctagtga cacagagaac actggacaga     1140

gagagccaag ccgagtacaa catcaccatc actgtcaccg acatggggac acccaggctg     1200

aaaaccgagc acaacataac ggtcctggtc tccgacgtca atgacaacgc ccccgccttc     1260

acccaaacct cctacaccct gttcgtccga gagaacaaca gccccgccct gcacatcggc     1320

agtgtcagcg ccacagacag agactcaggc accaacgccc aggtcaccta ctcgctgctg     1380

ccgccccaga atccacacct gcgcctcgcc tccctggtct ccatcaacgc ggacaacggc     1440

cacctgtttg ccctcaggtc gctggactac gaggccctgc aggcgttcga gttccgcgtg     1500

ggagccacag accgcggctc cccggcgctg agcagcgagg cgctggtgcg cgtgctggtg     1560

ctggacgcca acgacaactc gcccttcgtg ctgtatccgc tgcagaacgg ctcggcgcct     1620

tgcaccgagc tggtgccccg ggcggccgag ccgggctacc tggtgaccaa ggtggtggcg     1680

gtggacggtg actcgggcca gaacgcctgg ctgtcgtacc agctgctcaa ggccacggag     1740

cccgggctgt tcagcatgtg ggcgcacaat ggcgaggtgc gcaccgccag gctgctgagc     1800

gagcgcgacg cggccaagca caggctggtg gtgctggtca aggacaatgg cgagcctccg     1860

cgctcggcca ccgccacgct gcacgtgctc ctggtggacg gcttctccca gccctacctg     1920

ccgctgccgg aggcggcccc ggcccaggcc caggccgact cgctcactgt ctacctg        1977


<210>  4151
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  4151
gaatcgattc agtattccgt attggaggag acagaaagtg gcacgtttgt ggccaacttg       60

acaaaggacc tgggactgag ggtgggggag ctggcttcgc ggggcgctcg ggttgttttc      120

aaagggaaca gacaacattt gcagtttgat ccacagaccc atgatttact gctaaatgaa      180

aaactggacc gggaggagct gtgtggctcc actgagccgt gtgtgctacc tttccaagtg      240

ttactggaaa accccttgca gttttttcag gcttccttgc gagtcagaga tataaatgac      300

cacgccccgg aattccctgc cagagaaatg ctcctgaaaa tatcagaaat tactatgcca      360

ggaaagatat ttcctttgaa aatggcacac gatttagaca ccggcagcaa cggccttcag      420

aggtacacaa tcagctccaa ccctcacttc cacgttctca cccgcaatcg cagcgaaggc      480

aggaagttcc cggagctggt gctagacaaa ccgttggacc gcgaggagca gccccaactc      540

aggctaacgc tgatcgcgct ggatggcggg tctccgcccc ggtcagggac ctccgagatt      600

cagatccagg ttttggacat caatgacaac gtccccgagt ttgctcagga gctctatgaa      660

gcacaagtcc ctgagaacaa ccccctcggc tctctggtta ttaccgtctc agccagagat      720

ttagatgcag gatcgtttgg gaaggtatct tacgccctgt ttcaagtcga tgacgtcaac      780

caacccttcg aaataaacgc aatcacagga gaaattcggc tgagaaaggc tttggatttt      840

gaggaaattc agtcttatga cgtggatgtt gaggctacag atggtggagg cctatcagga      900

aaatgctctt tagtcgtcag ggtcctggac gtgaatgaca atgcccctga actcaccatg      960

tcgttcttca tcagcctcat cccagaaaac ttaccagaga tcacagtggc agttttcagt     1020

gtttcagatg cagactctgg acataaccaa caggttattt gttcaataga gaacaatctc     1080

ccctttctac taagaccttc cgtggagaat ttctacaccc tggtaacaga aggcgcgctg     1140

gacagagaga gcagagccga gtacaacatc actatcacgg tcactgattt ggggacacca     1200

aggctgaaaa cccagcagag cataactgtg caggtctccg acgtcaatga caacgtcccc     1260

gccttcaccc aaacctccta caccctgttc gtccgcgaga acaacagccc cgccctgcac     1320

atcggcagcg tcagcgccac agacagagac tcaggcatca acgcccaggt cacctactcg     1380

ctgctgccgc cccaggaccc gcacctgccc ctctcttccc tggtctccat caacgcggac     1440

aacggccacc tgtttgccct caggtcgctg gactacgagg ccctgcagtc tttcgagttc     1500

cgcgtgggcg ccacagaccg cggctccccg gcgttgagca gcgaggcgct ggtgcgcttg     1560

ctggtgctgg acgccaacga caactcgccc ttcgtgttgt acccgctgca gaacggctcc     1620

gcgccctgca ccgagctggt gccccgggcg gccgagccgg gctacctggt gaccaaggtg     1680

gtggcggtgg acggcgactc gggccagaac gcctggctgt cgtaccagct gctcaaggcc     1740

acggagctcg gtctgttcgg cgtgtgggcg cacaatggcg aggtgcgcac cgccaggctg     1800

ctgagcgagc gagacgcagc caagcacagg ctggtggtgc ttgtcaagga caatggcgag     1860

cctccgcgct cggccaccgc cacgctgcac gtgctcctgg tggacggctt ctcccagccc     1920

tacctgcctc tccctgaggc ggccccggcc caagcccagg ccgactctct caccgtctac     1980

ctg                                                                   1983


<210>  4152
<211>  1986
<212>  DNA
<213>  Homo Sapiens

<400>  4152
ggcgccgaac cgcttcggta ttttgtggcg gaggaaaccg agagaggcac ctttcttacc       60

aacttggcaa aagacctagg gttaggggta ggggaactga gagcccgggg aactagaatt      120

gtttcagacc agaacatgca aattttactg ctcagttcgc ttactggtga tctacttcta      180

aatgagaaat tggaccgaga ggaactgtgt ggccccagag agccctgtgt gctgcctttc      240

cagttgttat tggaaaaacc ttttcagatt ttccgtgctg aactatgggt cagagacatc      300

aatgatcacg ctccagtatt tctagacaga gagatttcct tgaaaatatt agaaagtacc      360

actccagggg cggcatttct cctagagagt gcacaggatt cagatgttgg aaccaacagc      420

ctgagtaact acaccatcag ccccaatgcc tatttccata ttaatgtcca tgatagcggg      480

gaggggaata tctatcccga attggtgctg aatcaagtgc tggatcggga agagatacca      540

gagttcagtt taaccctcac cgctttagac ggcggctctc ctccaagatc agggaccgcc      600

ctcgtgcgca ttctggttct agacgtaaat gacaacgccc ctgattttgt gcggtcgctc      660

tacaaggtgc aggtgcccga aaatagcccc gttggttcca tggttgtctc cgtgtcagcc      720

agagatttag ataccggaag taatggggaa atagcctatg cattttctta cgccactgaa      780

agaattctca aaacgtttca aatcaatcca acatctggca gtcttcatct taaagcgcaa      840

ttggactatg aggcaattca aacttacaca ttaactattc aggccaaaga cggcggcggg      900

ctttctggaa aatgcactgt agtggttgat gtaacagata taaacgataa tcgacccgag      960

ctgctcctgt cttcacttac tagcccaatt gcagaaaact cacccgagac agtcgtggct     1020

gtttttagga ttagagacag agattccggg aacaatggaa agacagtgtg ctccatccag     1080

gacgatctcc ccttcatcct gaagccatct gtcgaaaact tctatactct ggtaacagag     1140

aaacctttgg atcgagagag gaacactgag tacaacatca ccatcaccgt caccgacttg     1200

gggacaccca ggctgaaaac cgagcacaac ataaccgtgc tggtctccga cgtcaatgac     1260

aacgctcccg ccttcaccca aacctcctac accctgtttg tccgtgagaa caacagcccc     1320

gccctgccca tcggcagtgt cagcgccaca gacagagact caggcaccaa cgcccaggtc     1380

atctactccc tgctgccgtc ccaggacccg cacctgcccc tcgcctccct ggtctccatc     1440

aacgcggaca acggccacct gtttgccctc aggtccctgg actacgaggc cctgcaggcg     1500

ttcgagttcc gggtgggcgc cacagaccgc ggctcccccg cgctgagcag cgaggcgctg     1560

gtgcgcgtgc tggtgctgga cgccaacgac aactcgccct tcgtgctgta cccgctgcag     1620

aacagctccg cgccctgcac cgagccgttg ccccgggcgg ccgagccggg ctacctggtg     1680

accaaggtgg tggccgtgga cggcgactcg ggccagaacg cctggctgtc gtaccagctg     1740

ctcaaggcca cggagcccgg gctattcggc gtgtgggcgc acaatggcga ggtgcgtacc     1800

gccaggctgc tgagcgagcg cgacgcagcc aagcagaggc tggtggtgct ggtcaaggac     1860

aatggcgagc ctccgcgctc ggccaccgcc acgctgcacg tgctcctggt ggacggcttc     1920

tcccagccct acctgcggct cccggaggcg gccccggacc aggccaactc gctcaccgtc     1980

tacctg                                                                1986


<210>  4153
<211>  1992
<212>  DNA
<213>  Homo Sapiens

<400>  4153
ggttctgggt ttggacgtta ttcggtgact gaggaaacag agaaaggatc ctttgtggtc       60

aatctggcaa aggatctggg actagcagag ggggagctgg ctgcaagggg aaccagggtg      120

gtttccgatg ataacaaaca atacctgctc ctggattcac ataccgggaa tttgctcaca      180

aatgagaaac tggaccgaga gaagctgtgt ggccctaaag agccctgtat gctgtatttc      240

caaattttaa tggatgatcc ctttcagatt taccgggctg agctgagagt cagggatata      300

aatgatcact cgccagtgtt tcggcacaaa gagatggtct taaaaatatc agaaaataca      360

gctgaaggga cagcatttag actagaaaga gcacaggatc cagatgaagg tcataacagt      420

atccaaaact acacgatcag ctccaactct tttttccata ttaaaattag tggcagtgat      480

gaaggcatga tatatccaga gctagtgttg gacaaagcac tggatcggga ggagcaggaa      540

gagctcagct taaccctcac agcgctggat ggtgggtctc catccaggtc tgggacctcc      600

actatacgca ttgtggtctt ggatgtcaat gacaatgccc cacagtttgc ccaggctctg      660

tatgagaccc aggctccaga aaacagtcca gtagggtccc ttattgttaa agtgtctgca      720

ggagatgcag actcaggagt caatgcagaa gtatcctatt cattttttga tgcttctgaa      780

gatattttaa caacgtttca aatcaatcct ttttctgggg aaatctttct cagagaattg      840

cttgattatg agttagtaaa ttcttacaaa ataaatatac aggcaatgga cggcggaggc      900

ctttctgcaa gatgtacagt tttgataaaa gtattagatt ccaatgacaa tcctcctgaa      960

ctgatcatat catcactttc caactctgtt gctgaaaact ctcctgggat agtattggct     1020

gtttttaaga ttaaagacag agactccgga gaaaatggaa agacaatttg ctatgttcaa     1080

gataatctgc ctttttttct gaaaccgtct gttgacaatt tttacatcct aatgactgaa     1140

ggtgcactgg acagagagag caaagctgag tacaacatca ccatcaccgt cactgacttg     1200

gggacaccca ggctgaaaac cgagcacagc ataaccctgc aggtctccga cgtcaatgac     1260

aacgcccccg ccttcaccca aacctcctac accctgttcg tccgggagaa caacagcccc     1320

gccctgcaca tcggcagtgt cagcgccaca gacagagact caggcaccaa cgcccaggtc     1380

acctactcgc tgctgccgcc ccaggaccca cacctgcccc tcgcctccct ggtctccatc     1440

aacgcggaca atggccacct gtttgccctc aggtcgctgg actacgaggc cctgcaggct     1500

ttcgacttcc gcgtgggcgc ctcagaccgc ggctccccgg ctttgagcag cgaggcgctg     1560

gtgcgcgtac tggtgctgga cgccaacgac aactcgccct tcgtgctgta cccgctgcag     1620

aacggctccg cgccctgcac cgagctggtg ccccgggcgg ccgagccggg ctacctggtg     1680

accaaggtgg tggcggtgga cggcgactcg ggccagaacg cctggctgtc gtaccagctg     1740

ctcaaggcca cggagcccgg gctgttcggt gtgtgggcgc acaatgggga ggtgcgcacc     1800

gccaggctgc tgagcgagcg cgacgcagcc aagcacaggc tggtggtgct tgtcaaggac     1860

aatggcgagc ctcctcgctc ggccaccgcc acgctgcacg tgctcctggt ggacggcttc     1920

tcccagccct acctgcctct cccggaggcg gccccggccc aggcccaggc cgacttgctc     1980

accgtctacc tg                                                         1992


<210>  4154
<211>  1992
<212>  DNA
<213>  Homo Sapiens

<400>  4154
gaacagattc tctactcggt gtttgaggag caggaagaag gctcagtggt gggcaacatc       60

gccaaggacc tggggttggc gccccgggag ctggcggagc gcggagtccg catcgtctcc      120

agaggtagga cgcagctttt cgccctgaac ccgcgcagcg gcaccttggt caccgcgggt      180

aggatagaca gggaggagct ctgcgacaga tctccaaact gtgtgacaaa cctggagatt      240

cttctagaag atacagtgaa gattttgcgg gtagaggtgg aaataatcga tgttaatgat      300

aacccaccca gttttgggac agaacagagg gaaataaaag ttgctgaaaa tgaaaatcct      360

ggggcaagat ttcctcttcc tgaagctttt gatccggatg taggtgtaaa ctccctgcag      420

ggttaccagc tcaactcaaa cggttacttt tccctggacg tgcaaagtgg ggccgatggg      480

attaagtacc cagagctggt gctggaacgc gctctagatc gcgaggaaga ggcggttcac      540

cacctcgttc tcacggcctt cgatggaggt gacccggttc gctctggcac tgccaggatt      600

ctcataatac ttgtggatac caacgataat gctcccgtgt tcactcagcc cgagtaccac      660

gtaagtgttc gtgagaacgt tcctgtaggc actcggctac tcaccgtaaa agccactgat      720

ccagatgaag gagccaatgg agacgtgacg tattctttcc ggaaagtaag agacaaaata      780

tcacagctat ttcagttgaa ttctctgagt ggggatataa caatattggg gggtctagat      840

tatgaggact ctggattcta tgacatagat gtagaagccc atgatgggcc tggtctccga      900

gctagaagca aggtactggt gacagttctg gatgaaaatg acaacgcacc agaagtcaca      960

gttacatctc tcaccagctc agtccaggaa tcttcttccc cgggtacagt aattgcactt     1020

ttcaacgtgc atgacagtga ctcaggagga aatggcctag tcacatgttc tattccagat     1080

aatctgccat tcacacttga aaagacctat ggaaattatt atcggttgtt gacacacaga     1140

acactggaca gggaagaagt ctcagaatat aacatcactg taactgccac tgaccaggga     1200

actcctccac tgtctacaga aactcatatt tcactgcaag tgatggacat caatgacaac     1260

ccacccactt tccctcatgc ttcctactct gcttacattc ctgaaaacaa ccccagagga     1320

gcctccatct tatctatgac tgctcaagac cctgacagtg gtgacaatgc ccgaatcact     1380

tactccctgg ccgaagacac cttccagggt gcacctctgt cctcctatgt ctccatcaac     1440

tccaatacag ggatcctata tgctctttgc tccttcgact atgagcagtt tagagacctg     1500

cagctgctga tgacagccag tgacagtgga gaccctccac tcagcagcaa tgtgtcactg     1560

agcctctttg tgctggacca gaacgacaat gtccctgaga tcctgtaccc caccttccct     1620

actgatggct ccactggtgt ggagctggca ccccgctccg cagattccgg ctacctggtg     1680

accaaagtgg tggcagtgga cagagactca ggtcagaatg cctggctgtc ctacagccta     1740

ctcaagtcca gcgagccggg actatttgca gtggggctgc acacaggcga ggtgcgcacc     1800

gcacgggccc tgctggacag agacgcgctc aagcagaggc ttgtagtggt cgtccaggac     1860

catggccagc cccctctctc ggccaccgtc acactcactg tggctgtggc cgacagcatc     1920

ccagatgtcc tggctgactt gggcagcctc aagccttcag cagacccaga cgactcgggc     1980

ctcacactct at                                                         1992


<210>  4155
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  4155
gaaccgatcc gctacgctat tcccgaggag ctggacaggg gctcgctggt agggaacctc       60

gccaaggacc tggggtttgg cgtgggggat ttacctacta ggaacctgcg ggttattgca      120

gagaagaaat tctttaccgt gagccccgaa aatgggaact tacttgtgag cgaccgtata      180

gaccgagagg agatttgtgg caagaagtcg acgtgtgttc tggaatttga aatggttgct      240

gaaaagcctt taaacttttt tcatgtaact gtgctgatcc aggatattaa cgacaaccca      300

ccgaccttta gccaaaatat cactgagctg gaaatcagcg aactggctct cactggagcc      360

acatttgccc tggaatctgc gcaagatcct gatgtaggtg tcaattcgct gcagcagtac      420

tacctcagcc ctgatccgca cttctctttg attcagaagg agaacctgga tggcagtagg      480

tacccagagc tagtactgaa agcacccctg gacagggaag agcagccaca tcaccacctg      540

gtcctcacag ctgtggatgg gggcgagccc tccagaagct gtaccaccca gatcagggta      600

attgtcgcag atgcaaatga taacccccca gtatttactc aggacatgta cagggtcaat      660

gttgcagaga acctgcccgc tggctcctcc gtattaaaag tgatggccat tgacatggat      720

gagggcatca atgccgaaat catctatgcc ttcatcaata ttggcaagga agtgagacaa      780

ctgttcaagc tggacagtaa aacgggggaa ctcaccacta ttggagaact ggactttgaa      840

gagagagata gctacacaat tggggtggaa gcaaaggatg gtggacatca cactgcatat      900

tgtaaagtac agatagatat ttcagatgaa aatgacaatg ccccggagat aaccctggct      960

tctgaatccc aacatataca agaagatgct gagctgggga ctgccgttgc cctgatcaaa     1020

acacatgatc tagattctgg atttaatgga gaaatcctat gccaactaaa aggaaacttc     1080

ccctttaaaa tcgttcaaga taccaaaaac acatacaggt tggtgacaga tggagccctg     1140

gaccgggagc agatcccaga atacaatgtg acgatcacag ctaccgacaa aggcaatcca     1200

ccgctctcct ccagcaagac catcactctg cacatccttg atgtcaacga caacgttccc     1260

gttttccacc aggcctccta caccgtgcat gtagctgaga acaatccgcc tggagcctcc     1320

attgcgcatg tcagagcctc ggatcccgac ttgggaccta atggccttgt ctcctactac     1380

atcgtggcca gtgacctgga gccgcgggag ctgtcgtcct acgtgtccgt gagcgcgcgg     1440

agcggggtgg tgttcgcgca gcgagccttc gaccacgagc agctgcgtgc cttcgagctc     1500

actctgcagg cccgcgacca gggctcgcct acgctcagcg ccaacgtgag cctgcgcgtg     1560

ttggtggacg accgcaacga caatgcaccg ctggtgctgt acccagctct ggggcccgaa     1620

ggctctgcgc tcttcgatat ggtgccgcgc tctgcagagc ctggctacct ggtgaccaag     1680

gtggtggcgg tggacgcaga ctcgggatac aacgcctggc tgtcctacca cattgtgcag     1740

gccagcgagc ccgggctgtt cagcctgggc ctgcgcacgg gtgaggtgcg cacggcgcgt     1800

accttgggcg acagggaggc cgcccgccag cgcctgctgg tcactgtgcg tgatggagga     1860

cagcagcctc tttcagccac cgtcatgctg cacctaatct tcgcagatag cttgcaagag     1920

atacaacctg accttagcga ccgccccact ccctctgacc ctcaggcgga gctacagttt     1980

cac                                                                   1983


<210>  4156
<211>  1983
<212>  DNA
<213>  Homo Sapiens

<400>  4156
gagccgatcc gctactcgat tccggaggag ctggccaagg gctcggtggt ggggaacctc       60

gctaaggatc tagggctcag tgtcctggat gtgtcggctc gcaagctgcg agtgagcgcg      120

gagaagctgc acttcagcgt agacgcggag agcggggact tacttgtgaa gaaccgaata      180

gaccgtgagc aaatatgcaa agagagaaga agatgtgagt tgcaattgga agctgtggtg      240

gaaaatcctt taaatatttt tcatgtcatt gtggtgattg aggatgttaa tgaccacgcc      300

cctcaatttg ataaaaagga aatacattta gaaattttcg aatctgcatc cgctggtaca      360

cgactatcgc ttgaccctgc cacggatcct gatataaaca taaactcaat taaagattat      420

aagataaact ctaatcctta tttttcatta atggttagag ttaattccga tggtggcaaa      480

tacccagagt tatctctgga gaaactccta gaccgggaag aacagagatc tcatagcttg      540

atattgactg ccttggacgg aggggaccca ccaagaagtg ccaccgctca catagaaatt      600

tctgtcaagg ataccaatga taaccccccg gttttcagca gagacgaata tagaattagt      660

cttagtgaaa atctgccccc tgggtcccct gtgttgcaag tgacagccac tgaccaggat      720

gagggggtca atgctgagat aaactactac ttccgaagca ctgcccagag cacaaaacat      780

atgttctcat tggatgagaa aacaggtatg attaagaata accagtcatt tgattttgaa      840

gatgtagaaa ggtacaccat ggaagtggaa gcgaaggacg gaggtggtct ctctacccag      900

tgtaaagtaa tcatagaaat ccttgatgaa aacgacaaca gcccagaaat aatcatcact      960

tctctctctg atcagatttt ggagaattca cctccaggaa tggttgttgc cctcttcaaa     1020

acacgggatc tggatttcgg aggaaatgga gaagtcaggt gtaatataga aacagacatt     1080

ccattcaaga tttattcttc ttccaataac tactacaaac tggtgacaga tggagccctg     1140

gaccgagagc agacaccaga atacaatgtc accatcgtag ccactgacag gggcaagccg     1200

cctctttctt ccagtagaag catcaccttg tatgtcgctg acatcaacga caacgcccca     1260

gttttcgacc agacgtccta cgtggtccac gtggccgaga acaacccgcc aggagcctcc     1320

attgcgcaag tgagcgcctc tgacccggat ttggggctca atggccacat ctcctactct     1380

atagtggcga gtgacctaga gcccctggcg gtgtcgtcat acgtgtcagt gagcgcgcag     1440

agcggggtgg tgttcgcgca gcgcgccttt gatcacgagc agctgcgcgc cttcgcgctc     1500

acgctgcagg cccgcgacca cggctcgccc acgctcagcg ccaacgtgag cctgcgcgtg     1560

ttggtgggag accgcaatga caacgcaccg cgggtgctgt acccagctct gggtcctgac     1620

ggctccgcgt tcttcgatat ggtacctcgc tctgcagagc ccggctacct agtgactaag     1680

gtggtagcgg tggacgccga ctcgggacac aacgcctggc tgtcctacca cgtgctgcag     1740

gccagtgagc ccggactctt cagcctgggg ctgcgcactg gggaggtgcg cacggctcga     1800

gccttaggcg acagggacgc agcccgccag cgcctgctgg tcgctgtgcg tgacggtgga     1860

cagccgccac tctctgccac cgccacgctt catctggtct tcgcagacaa cttgcaagag     1920

atactgccag acctcagcga ccgccctgta ctctctgacc cccaggctga actgcagttt     1980

tac                                                                   1983


<210>  4157
<211>  1986
<212>  DNA
<213>  Homo Sapiens

<400>  4157
gtcattcact atgagatccc ggaggaaaga gagaagggtt tcgctgtggg caacgtggtc       60

gcgaaccttg gtttggatct cggtagcctc tcagcccgca ggttccgggt ggtgtctgga      120

gctagccgaa gattctttga ggtgaaccgg gagaccggag agatgtttgt gaacgaccgt      180

ctggatcgag aggagctgtg tgggacactg ccctcttgca ctgtaactct ggagttggta      240

gtggagaacc cgctggagct gttcagcgtg gaagtggtga tccaggacat caacgacaac      300

aatcctgctt tccctaccca ggaaatgaaa ttggagatta gcgaggccgt ggctccgggg      360

acgcgctttc cgctcgagag cgcgcacgat cccgatgtgg gaagcaactc tttacaaacc      420

tatgagctga gccgaaatga atactttgcg cttcgcgtgc agacgcggga ggacagcacc      480

aagtacgcgg agctggtgtt ggagcgcgcc ctggaccgag aacgggagcc tagtctccag      540

ttagtgctga cggcgttgga cggagggacc ccagctctct ccgccagcct gcctattcac      600

atcaaggtgc tggacgcgaa tgacaatgcg cctgtcttca accagtcctt gtaccgggcg      660

cgcgtcctgg aggatgcacc ctccggcacg cgcgtggtac aagtccttgc aacggatctg      720

gatgaaggcc ccaacggtga aattatttac tccttcggca gccacaaccg cgccggcgtg      780

cggcaactat tcgccttaga ccttgtaacc gggatgctga caatcaaggg tcggctggac      840

ttcgaggaca ccaaactcca tgagatttac atccaggcca aagacaaggg cgccaatccc      900

gaaggagcac attgcaaagt gttggtggag gttgtggatg tgaatgacaa cgccccggag      960

atcacagtca cctccgtgta cagcccagta cccgaggatg cccctctggg gactgtcatc     1020

gctttgctca gtgtgactga cctggatgct ggcgagaacg ggctggtgac ctgcgaagtt     1080

ccaccgggtc tccctttcag ccttacttct tccctcaaga attacttcac tttgaaaacc     1140

agtgcagacc tggatcggga gactgtgcca gaatacaacc tcagcatcac cgcccgagac     1200

gccggaaccc cttccctctc agcccttaca atagtgcgtg ttcaagtgtc cgacatcaat     1260

gacaaccctc cacaatcttc tcaatcttcc tacgacgttt acattgaaga aaacaacctc     1320

cccggggctc caatactaaa cctaagtgtc tgggaccccg acgccccgca gaatgctcgg     1380

ctttctttct ttctcttgga gcaaggagct gaaaccgggc tagtgggtcg ctatttcaca     1440

ataaatcgtg acaatggcat agtgtcatcc ttagtgcccc tagactatga ggatcggcgg     1500

gaatttgaat taacagctca tatcagcgat gggggcaccc cggtcctagc caccaacatc     1560

agcgtgaaca tatttgtcac tgatcgcaat gacaatgccc cccaggtcct atatcctcgg     1620

ccaggtggga gctcggtgga gatgctgcct cgaggtacct cagctggcca cctagtgtca     1680

cgggtggtag gctgggacgc ggatgcaggg cacaatgcct ggctctccta cagtctcttg     1740

ggatccccta accagagcct ttttgccata gggctgcaca ctggtcaaat cagtactgcc     1800

cgtccagtcc aagacacaga ttcacccagg cagactctca cggtcttgat caaagacaat     1860

ggggagcctt cgctctccac cactgctacc ctcactgtgt cagtaaccga ggactctcct     1920

gaagcccgag ccgagttccc ctctggctct gccccccggg agcagaaaaa aaatctcacc     1980

ttttat                                                                1986


<210>  4158
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  4158
gcgcggccgg taaaggagcc ccgcggccta agcgcagcgt ctccgccctt ggctgagact       60

ggcgctcctc gccgcttccg gcggtcagtg ccccgaggtg aggcggcggg ggcggtgcag      120

gagctggcgc gggcgctggc gcatctgctg gaggccgaac gtcaggagcg ggcgcgggcc      180

gaggcgcagg aggctgagga tcagcaggcg cgcgtcctgg cgcagctgct gcgcgtctgg      240

ggcgcccccc gcaactctga tccggctctg ggcctggacg acgaccccga cgcgcctgca      300

gcgcagctcg ctcgcgctct gctccgcgcc cgccttgacc ctgccgccct agcagcccag      360

cttgtccccg cgcccgtccc cgccgcggcg ctccgacccc ggcccccggt ctacgacgac      420

ggccccgcgg gcccggatgc tgaggaggca ggcgacgaga cacccgacgt ggaccccgag      480

ctgttgaggt acttgctggg acggattctt gcgggaagcg cggactccga gggggtggca      540

gccccgcgcc gcctccgccg tgccgccgac cacgatgtgg gctctgagct gccccctgag      600

ggcgtgctgg gggcgctgct gcgtgtgaaa cgcctagaga ccccggcgcc ccaggtgcct      660

gcacgccgcc tcttgccacc c                                                681


<210>  4159
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  4159
ggggcaggtt ggcagctgtt ttgcaggact gtgtggtcag cacactcggg gcctacacgg       60

atggccacag ccatcgcccg ctgcgcccca gatgaggagc tgctgagctg ctccagtttc      120

tccaggagtg ggaagcggcg gggcgagcgc atggaggccc aagggggcaa gctggtctgc      180

cgggcccaca acgcttttgg gggtgagggt gtctacgcca ttgccaggtg ctgcctgcta      240

ccccaggcca actgcagcgt ccacacagct ccaccagctg aggccagcat ggggacccgt      300

gtccactgcc accaacaggg ccacgtcctc acaggctgca gctcccactg ggaggtggag      360

gaccttggca cccacaagcc gcctgtgctg aggccacgag gtcagcccaa ccagtgcgtg      420

ggccacaggg aggccagcat ccacgcttcc tgctgccatg ccccaggtct ggaatgcaaa      480

gtcaaggagc atggaatccc ggcccctcag gagcaggtga ccgtggcctg cgaggagggc      540

tggaccctga ctggctgcag tgccctccct gggacctccc acgtcctggg ggcctacgcc      600

gtagacaaca cgtgtgtagt caggagccgg gacgtcagca ctacaggcag caccagcgaa      660

gaggccgtga cagccgttgc catctgctgc cggagccggc acctggcgca ggcctcccag      720

gagctccag                                                              729


<210>  4160
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  4160
ccaggatggt tcttagactc cccagacagg ccctggaacc cccccacctt ctccccagcc       60

ctgctcgtgg tgaccgaagg ggacaacgcc accttcacct gcagcttctc caacacatcg      120

gagagcttcg tgctaaactg gtaccgcatg agccccagca accagacgga caagctggcc      180

gctttccccg aggaccgcag ccagcccggc caggactgcc gcttccgtgt cacacaactg      240

cccaacgggc gtgacttcca catgagcgtg gtcagggccc ggcgcaatga cagcggcacc      300

tacctctgtg gggccatctc cctggccccc aaggcgcaga tcaaagagag cctgcgggca      360

gagctcaggg tgacagagag aagggcagaa gtgcccacag cccaccccag cccctcaccc      420

aggccagccg gccagttcca aaccctggtg                                       450


<210>  4161
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  4161
ttattcacag tgacagtccc taaggaactg tacataatag agcatggcag caatgtgacc       60

ctggaatgca actttgacac tggaagtcat gtgaaccttg gagcaataac agccagtttg      120

caaaaggtgg aaaatgatac atccccacac cgtgaaagag ccactttgct ggaggagcag      180

ctgcccctag ggaaggcctc gttccacata cctcaagtcc aagtgaggga cgaaggacag      240

taccaatgca taatcatcta tggggtcgcc tgggactaca agtacctgac tctgaaagtc      300

aaagcttcct acaggaaaat aaacactcac atcctaaagg ttccagaaac agatgaggta      360

gagctcacct gccaggctac aggttatcct ctggcagaag tatcctggcc aaacgtcagc      420

gttcctgcca acaccagcca ctccaggacc cctgaaggcc tctaccaggt caccagtgtt      480

ctgcgcctaa agccaccccc tggcagaaac ttcagctgtg tgttctggaa tactcacgtg      540

agggaactta ctttggccag cattgacctt caaagtcaga tggaacccag gacccatcca      600

act                                                                    603


<210>  4162
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  4162
agcatcgagg aagctgtccc cgctgtctgc aagaccagga cggtcattta cgagattcct       60

cggagtcagg tcgaccccac gtccgccaac ttcctgatct ggcccccgtg cgtggaggtg      120

aaacgctgca ccggctgctg caacacgagc agtgtcaagt gccagccctc ccgcgtccac      180

caccgcagcg tcaaggtggc caaggtggaa tacgtcagga agaagccaaa attaaaagaa      240

gtccaggtga ggttagagga gcatttggag tgcgcctgcg cgaccacaag cctgaatccg      300

gattatcggg aagaggacac ggatgtgagg                                       330


<210>  4163
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  4163
agcctgggtt ccctgaccat tgctgagccg gccatgatcg ccgagtgcaa gacgcgcacc       60

gaggtgttcg agatctcccg gcgcctcata gaccgcacca acgccaactt cctggtgtgg      120

ccgccctgtg tggaggtgca gcgctgctcc ggctgctgca acaaccgcaa cgtgcagtgc      180

cgccccaccc aggtgcagct gcgacctgtc caggtgagaa agatcgagat tgtgcggaag      240

aagccaatct ttaagaaggc cacggtgacg ctggaagacc acctggcatg caagtgtgag      300

acagtggcag ctgcacggcc tgtgacc                                          327


<210>  4164
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  4164
gaatccaacc tgagtagtaa attccagttt tccagcaaca aggaacagaa cggagtacaa       60

gatcctcagc atgagagaat tattactgtg tctactaatg gaagtattca cagcccaagg      120

tttcctcata cttatccaag aaatacggtc ttggtatgga gattagtagc agtagaggaa      180

aatgtatgga tacaacttac gtttgatgaa agatttgggc ttgaagaccc agaagatgac      240

atatgcaagt atgattttgt agaagttgag gaacccagtg atggaactat attagggcgc      300

tggtgtggtt ctggtactgt accaggaaaa cagatttcta aaggaaatca aattaggata      360

agatttgtat ctgatgaata ttttccttct gaaccagggt tctgcatcca ctacaacatt      420

gtcatgccac aattcacaga agctgtgagt ccttcagtgc tacccccttc agctttgcca      480

ctggacctgc ttaataatgc tataactgcc tttagtacct tggaagacct tattcgatat      540

cttgaaccag agagatggca gttggactta gaagatctat ataggccaac ttggcaactt      600

cttggcaagg cttttgtttt tggaagaaaa tccagagtgg tggatctgaa ccttctaaca      660

gaggaggtaa gattatacag ctgcacacct cgtaacttct cagtgtccat aagggaagaa      720

ctaaagagaa ccgataccat tttctggcca ggttgtctcc tggttaaacg ctgtggtggg      780

aactgtgcct gttgtctcca caattgcaat gaatgtcaat gtgtcccaag caaagttact      840

aaaaaatacc acgaggtcct tcagttgaga ccaaagaccg gtgtcagggg attgcacaaa      900

tcactcaccg acgtggccct ggagcaccat gaggagtgtg actgtgtgtg cagagggagc      960

acaggagga                                                              969


<210>  4165
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4165
tcataccatg accggaagtc aaaagttgac ctggataggc tcaatgatga tgccaagcgt       60

tacagttgca ctcccaggaa ttactcggtc aatataagag aagagctgaa gttggccaat      120

gtggtcttct ttccacgttg cctcctcgtg cagcgctgtg gaggaaattg tggctgtgga      180

actgtcaact ggaggtcctg cacatgcaat tcagggaaaa ccgtgaaaaa gtatcatgag      240

gtattacagt ttgagcctgg ccacatcaag aggaggggta gagctaagac catggctcta      300

gttgacatcc agttggatca ccatgaacga tgtgattgta tctgcagctc aagaccacct      360

cga                                                                    363


<210>  4166
<211>  1515
<212>  DNA
<213>  Homo Sapiens

<400>  4166
cagctttcat taccctctat ccttccaaat gaaaatgaaa aggttgtgca gctgaattca       60

tccttttctc tgagatgctt tggggagagt gaagtgagct ggcagtaccc catgtctgaa      120

gaagagagct ccgatgtgga aatcagaaat gaagaaaaca acagcggcct ttttgtgacg      180

gtcttggaag tgagcagtgc ctcggcggcc cacacagggt tgtacacttg ctattacaac      240

cacactcaga cagaagagaa tgagcttgaa ggcaggcaca tttacatcta tgtgccagac      300

ccagatgtag cctttgtacc tctaggaatg acggattatt tagtcatcgt ggaggatgat      360

gattctgcca ttataccttg tcgcacaact gatcccgaga ctcctgtaac cttacacaac      420

agtgaggggg tggtacctgc ctcctacgac agcagacagg gctttaatgg gaccttcact      480

gtagggccct atatctgtga ggccaccgtc aaaggaaaga agttccagac catcccattt      540

aatgtttatg ctttaaaagc aacatcagag ctggatctag aaatggaagc tcttaaaacc      600

gtgtataagt caggggaaac gattgtggtc acctgtgctg tttttaacaa tgaggtggtt      660

gaccttcaat ggacttaccc tggagaagtg aaaggcaaag gcatcacaat gctggaagaa      720

atcaaagtcc catccatcaa attggtgtac actttgacgg tccccgaggc cacggtgaaa      780

gacagtggag attacgaatg tgctgcccgc caggctacca gggaggtcaa agaaatgaag      840

aaagtcacta tttctgtcca tgagaaaggt ttcattgaaa tcaaacccac cttcagccag      900

ttggaagctg tcaacctgca tgaagtcaaa cattttgttg tagaggtgcg ggcctaccca      960

cctcccagga tatcctggct gaaaaacaat ctgactctga ttgaaaatct cactgagatc     1020

accactgatg tggaaaagat tcaggaaata aggtatcgaa gcaaattaaa gctgatccgt     1080

gctaaggaag aagacagtgg ccattatact attgtagctc aaaatgaaga tgctgtgaag     1140

agctatactt ttgaactgtt aactcaagtt ccttcatcca ttctggactt ggtcgatgat     1200

caccatggct caactggggg acagacggtg aggtgcacag ctgaaggcac gccgcttcct     1260

gatattgagt ggatgatatg caaagatatt aagaaatgta ataatgaaac ttcctggact     1320

attttggcca acaatgtctc aaacatcatc acggagatcc actcccgaga caggagtacc     1380

gtggagggcc gtgtgacttt cgccaaagtg gaggagacca tcgccgtgcg atgcctggct     1440

aagaatctcc ttggagctga gaaccgagag ctgaagctgg tggctcccac cctgcgttct     1500

gaactcacgg tggct                                                      1515


<210>  4167
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  4167
ctggtcgtca cacccccggg gccagagctt gtcctcaatg tctccagcac cttcgttctg       60

acctgctcgg gttcagctcc ggtggtgtgg gaacggatgt cccaggagcc cccacaggaa      120

atggccaagg cccaggatgg caccttctcc agcgtgctca cactgaccaa cctcactggg      180

ctagacacgg gagaatactt ttgcacccac aatgactccc gtggactgga gaccgatgag      240

cggaaacggc tctacatctt tgtgccagat cccaccgtgg gcttcctccc taatgatgcc      300

gaggaactat tcatctttct cacggaaata actgagatca ccattccatg ccgagtaaca      360

gacccacagc tggtggtgac actgcacgag aagaaagggg acgttgcact gcctgtcccc      420

tatgatcacc aacgtggctt ttttggtatc tttgaggaca gaagctacat ctgcaaaacc      480

accattgggg acagggaggt ggattctgat gcctactatg tctacagact ccaggtgtca      540

tccatcaacg tctctgtgaa cgcagtgcag actgtggtcc gccagggtga gaacatcacc      600

ctcatgtgca ttgtgatcgg gaatgaggtg gtcaacttcg agtggacata cccccgcaaa      660

gaaagtgggc ggctggtgga gccggtgact gacttcctct tggatatgcc ttaccacatc      720

cgctccatcc tgcacatccc cagtgccgag ttagaagact cggggaccta cacctgcaat      780

gtgacggaga gtgtgaatga ccatcaggat gaaaaggcca tcaacatcac cgtggttgag      840

agcggctacg tgcggctcct gggagaggtg ggcacactac aatttgctga gctgcatcgg      900

agccggacac tgcaggtagt gttcgaggcc tacccaccgc ccactgtcct gtggttcaaa      960

gacaaccgca ccctgggcga ctccagcgct ggcgaaatcg ccctgtccac gcgcaacgtg     1020

tcggagaccc ggtatgtgtc agagctgaca ctggttcgcg tgaaggtggc agaggctggc     1080

cactacacca tgcgggcctt ccatgaggat gctgaggtcc agctctcctt ccagctacag     1140

atcaatgtcc ctgtccgagt gctggagcta agtgagagcc accctgacag tggggaacag     1200

acagtccgct gtcgtggccg gggcatgccc cagccgaaca tcatctggtc tgcctgcaga     1260

gacctcaaaa ggtgtccacg tgagctgccg cccacgctgc tggggaacag ttccgaagag     1320

gagagccagc tggagactaa cgtgacgtac tgggaggagg agcaggagtt tgaggtggtg     1380

agcacactgc gtctgcagca cgtggatcgg ccactgtcgg tgcgctgcac gctgcgcaac     1440

gctgtgggcc aggacacgca ggaggtcatc gtggtgccac actccttgcc ctttaaggtg     1500


<210>  4168
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  4168
caacaccttc ccaagaacaa gcgtccaaaa gaaccaggag agaatagaat caaacctacc       60

aacaagaagg tgaagcccaa aattcctaaa atgaaggaca gggactcagc caattcagca      120

ccaaagacgc agtctatcat gatgcaagtg ctggataaag gtcgcttcca gaaacccgcc      180

gctaccctga gtctgctggc ggggcaaact gtagagcttc gatgtaaagg gagtagaatt      240

gggtggagct accctgcgta tctggacacc tttaaggatt ctcgcctcag cgtcaagcag      300

aatgagcgct acggccagtt gactctggtc aactccacct cggcagacac aggtgaattc      360

agctgctggg tgcagctctg cagcggctac atctgcagga aggacgaggc caaaacgggc      420

tccacctaca tcttttttac agagaaagga gaactctttg taccttctcc cagctacttc      480

gatgttgtct acttgaaccc ggacagacag gctgtggttc cttgtcgggt gaccgtgctg      540

tcggccaaag tcacgctcca cagggaattc ccagccaagg agatcccagc caatggaacg      600

gacattgttt atgacatgaa gcggggcttt gtgtatctgc aacctcattc cgagcaccag      660

ggtgtggttt actgcagggc ggaggccggg ggcagatctc agatctccgt caagtaccag      720

ctgctctacg tggcggttcc cagtggccct ccctcaacaa ccatcttggc ttcttcaaac      780

aaagtgaaaa gtggggacga catcagtgtg ctctgcactg tcctggggga gcccgatgtg      840

gaggtggagt tcacctggat cttcccaggg cagaaggatg aaaggcctgt gacgatccaa      900

gacacttgga ggttgatcca cagaggactg ggacacacca cgagaatctc ccagagtgtc      960

attacagtgg aagacttcga gacgattgat gcaggatatt acatttgcac tgctcagaat     1020

cttcaaggac agaccacagt agctaccact gttgagtttt cc                        1062


<210>  4169
<211>  1722
<212>  DNA
<213>  Homo Sapiens

<400>  4169
caagaaaact ctttcacaat caacagtgtt gacatgaaga gcctgccgga ctggacggtg       60

caaaatggga agaacctgac cctgcagtgc ttcgcggatg tcagcaccac ctctcacgtc      120

aagcctcagc accagatgct gttctataag gatgacgtgc tgttttacaa catctcctcc      180

atgaagagca cagagagtta ttttattcct gaagtccgga tctatgactc agggacatat      240

aaatgtactg tgattgtgaa caacaaagag aaaaccactg cagagtacca ggtgttggtg      300

gaaggagtgc ccagtcccag ggtgacactg gacaagaaag aggccatcca aggtgggatc      360

gtgagggtca actgttctgt cccagaggaa aaggccccaa tacacttcac aattgaaaaa      420

cttgaactaa atgaaaaaat ggtcaagctg aaaagagaga agaattctcg agaccagaat      480

tttgtgatac tggaattccc cgttgaggaa caggaccgcg ttttatcctt ccgatgtcaa      540

gctaggatca tttctgggat ccatatgcag acctcagaat ctaccaagag tgaactggtc      600

accgtgacgg aatccttctc tacacccaag ttccacatca gccccaccgg aatgatcatg      660

gaaggagctc agctccacat taagtgcacc attcaagtga ctcacctggc ccaggagttt      720

ccagaaatca taattcagaa ggacaaggcg attgtggccc acaacagaca tggcaacaag      780

gctgtgtact cagtcatggc catggtggag cacagtggca actacacgtg caaagtggag      840

tccagccgca tatccaaggt cagcagcatc gtggtcaaca taacagaact attttccaag      900

cccgaactgg aatcttcctt cacacatctg gaccaaggtg aaagactgaa cctgtcctgc      960

tccatcccag gagcacctcc agccaacttc accatccaga aggaagatac gattgtgtca     1020

cagactcaag atttcaccaa gatagcctca aagtcggaca gtgggacgta tatctgcact     1080

gcaggtattg acaaagtggt caagaaaagc aacacagtcc agatagtcgt atgtgaaatg     1140

ctctcccagc ccaggatttc ttatgatgcc cagtttgagg tcataaaagg acagaccatc     1200

gaagtccgtt gcgaatcgat cagtggaact ttgcctattt cttaccaact tttaaaaaca     1260

agtaaagttt tggagaatag taccaagaac tcaaatgatc ctgcggtatt caaagacaac     1320

cccactgaag acgtcgaata ccagtgtgtt gcagataatt gccattccca cgccaaaatg     1380

ttaagtgagg ttctgagggt gaaggtgata gccccggtgg atgaggtcca gatttctatc     1440

ctgtcaagta aggtggtgga gtctggagag gacattgtgc tgcaatgtgc tgtgaatgaa     1500

ggatctggtc ccatcaccta taagttttac agagaaaaag agggcaaacc cttctatcaa     1560

atgacctcaa atgccaccca ggcattttgg accaagcaga aggctaacaa ggaacaggag     1620

ggagagtatt actgcacagc cttcaacaga gccaaccacg cctccagtgt ccccagaagc     1680

aaaatactga cagtcagagt cattcttgcc ccatggaaga aa                        1722


<210>  4170
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  4170
gaagctgaag aagatgggga cctgcagtgc ctgtgtgtga agaccacctc ccaggtccgt       60

cccaggcaca tcaccagcct ggaggtgatc aaggccggac cccactgccc cactgcccaa      120

ctgatagcca cgctgaagaa tggaaggaaa atttgcttgg acctgcaagc cccgctgtac      180

aagaaaataa ttaagaaact tttggagagt                                       210


<210>  4171
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  4171
ctgcctgctg tgccccccca gcagtgggcc ttgtctgctg ggaacggctc gtcagaggtg       60

gaagtggtac ccttccagga agtgtggggc cgcagctact gccgggcgct ggagaggctg      120

gtggacgtcg tgtccgagta ccccagcgag gtggagcaca tgttcagccc atcctgtgtc      180

tccctgctgc gctgcaccgg ctgctgcggc gatgagaatc tgcactgtgt gccggtggag      240

acggccaatg tcaccatgca gctcctaaag atccgttctg gggaccggcc ctcctacgtg      300

gagctgacgt tctctcagca cgttcgctgc gaatgccggc ctctgcggga gaagatgaag      360

ccggaaagga ggagacccaa gggcaggggg aagaggagga gagagaagca gagacccaca      420

gactgccacc tgtgcggcga tgctgttccc cggagg                                456


<210>  4172
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  4172
caggagacag aagacccggc ctgctgcagc cccatagtgc cccggaacga gtggaaggcc       60

ctggcatcag agtgcgccca gcacctgagc ctgcccttac gctatgtggt ggtatcgcac      120

acggcgggca gcagctgcaa cacccccgcc tcgtgccagc agcaggcccg gaatgtgcag      180

cactaccaca tgaagacact gggctggtgc gacgtgggct acaacttcct gattggagaa      240

gacgggctcg tatacgaggg ccgtggctgg aacttcacgg gtgcccactc aggtcactta      300

tggaacccca tgtccattgg catcagcttc atgggcaact acatggatcg ggtgcccaca      360

ccccaggcca tccgggcagc ccagggtcta ctggcctgcg gtgtggctca gggagccctg      420

aggtccaact atgtgctcaa aggacaccgg gatgtgcagc gtacactctc tccaggcaac      480

cagctctacc acctcatcca gaattggcca cactaccgct ccccc                      525


<210>  4173
<211>  1860
<212>  DNA
<213>  Homo Sapiens

<400>  4173
aagagtccca tatttggtcc cgaggaggtg aatagtgtgg aaggtaactc agtgtccatc       60

acgtgctact acccacccac ctctgtcaac cggcacaccc ggaagtactg gtgccggcag      120

ggagctagag gtggctgcat aaccctcatc tcctcggagg gctacgtctc cagcaaatat      180

gcaggcaggg ctaacctcac caacttcccg gagaacggca catttgtggt gaacattgcc      240

cagctgagcc aggatgactc cgggcgctac aagtgtggcc tgggcatcaa tagccgaggc      300

ctgtcctttg atgtcagcct ggaggtcagc cagggtcctg ggctcctaaa tgacactaaa      360

gtctacacag tggacctggg cagaacggtg accatcaact gccctttcaa gactgagaat      420

gctcaaaaga ggaagtcctt gtacaagcag ataggcctgt accctgtgct ggtcatcgac      480

tccagtggtt atgtaaatcc caactataca ggaagaatac gccttgatat tcagggtact      540

ggccagttac tgttcagcgt tgtcatcaac caactcaggc tcagcgatgc tgggcagtat      600

ctctgccagg ctggggatga ttccaatagt aataagaaga atgctgacct ccaagtgcta      660

aagcccgagc ccgagctggt ttatgaagac ctgaggggct cagtgacctt ccactgtgcc      720

ctgggccctg aggtggcaaa cgtggccaaa tttctgtgcc gacagagcag tggggaaaac      780

tgtgacgtgg tcgtcaacac cctggggaag agggccccag cctttgaggg caggatcctg      840

ctcaaccccc aggacaagga tggctcattc agtgtggtga tcacaggcct gaggaaggag      900

gatgcagggc gctacctgtg tggagcccat tcggatggtc agctgcagga aggctcgcct      960

atccaggcct ggcaactctt cgtcaatgag gagtccacga ttccccgcag ccccactgtg     1020

gtgaaggggg tggcaggagg ctctgtggcc gtgctctgcc cctacaaccg taaggaaagc     1080

aaaagcatca agtactggtg tctctgggaa ggggcccaga atggccgctg ccccctgctg     1140

gtggacagcg aggggtgggt taaggcccag tacgagggcc gcctctccct gctggaggag     1200

ccaggcaacg gcaccttcac tgtcatcctc aaccagctca ccagccggga cgccggcttc     1260

tactggtgtc tgaccaacgg cgatactctc tggaggacca ccgtggagat caagattatc     1320

gaaggagaac caaacctcaa ggtaccaggg aatgtcacgg ctgtgctggg agagactctc     1380

aaggtcccct gtcactttcc atgcaaattc tcctcgtacg agaaatactg gtgcaagtgg     1440

aataacacgg gctgccaggc cctgcccagc caagacgaag gccccagcaa ggccttcgtg     1500

aactgtgacg agaacagccg gcttgtctcc ctgaccctga acctggtgac cagggctgat     1560

gagggctggt actggtgtgg agtgaagcag ggccacttct atggagagac tgcagccgtc     1620

tatgtggcag ttgaagagag gaaggcagcg gggtcccgcg atgtcagcct agcgaaggca     1680

gacgctgctc ctgatgagaa ggtgctagac tctggttttc gggagattga gaacaaagcc     1740

attcaggatc ccaggctttt tgcagaggaa aaggcggtgg cagatacaag agatcaagcc     1800

gatgggagca gagcatctgt ggattccggc agctctgagg aacaaggtgg aagctccaga     1860


<210>  4174
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  4174
tcaggaggtt gcttctggga taatgggcat ttatatagag aggaccagac ttcacctgca       60

ccgggtctac gttgtttaaa ttggcttgac gcgcaaagcg ggctggcatc cgcgccggta      120

agcggtgccg ggaatcatag ttactgcagg aatccagatg aggaccctcg tggaccttgg      180

tgttatgtat caggagaagc aggtgtgcca gaaaaaaggc cctgcgagga tctaagatgt      240

cccgaaacga catcccaggc gctgcctgcc ttcactaccg aaatacagga agcaagtgaa      300

gggcctggtg cagatgaagt acaagtcttc gcgcctgcta atgccctgcc agcacgttcc      360

gaagcagcgg cagtacagcc cgtgattggc ataagccaga gagttaggat gaatagcaaa      420

gaaaaaaagg accttggtac g                                                441


<210>  4175
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  4175
atgggtcggc ccctgctgct gcccctactg cccctgctgc tgccgccagc atttctgcag       60

cctagtggct ccacaggatc tggtccaagc tacctttatg gggtcactca accaaaacac      120

ctctcagcct ccatgggtgg ctctgtggaa atccccttct ccttctatta cccctgggag      180

ttagccacag ctcccgacgt gagaatatcc tggagacggg gccacttcca cgggcagtcc      240

ttctacagca caaggccgcc ttccattcac aaggattatg tgaaccggct ctttctgaac      300

tggacagagg gtcagaagag cggcttcctc aggatctcca acctgcagaa gcaggaccag      360

tctgtgtatt tctgccgagt tgagctggac acacggagct cagggaggca gcagtggcag      420

tccatcgagg ggaccaaact ctccatcacc cagggtcagc agcggactaa agccacaacc      480

ccagccaggg aacccttcca aaacacagag gagccatatg agaatatcag gaatgaagga      540

caaaatacag atcccaagct aaatcccaag ctccacctca cccagagcac ctcccagcca      600

ccgtcccctc aagagccccc agaacgagac cctgtactct gtcttaaagg cctaaccaat      660

ggacagccct ctcaagac                                                    678


<210>  4176
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  4176
cagcctggtg gctccacagg atctggtcca agctaccttt atggggtcac tcaaccaaaa       60

cacctctcag cctccatggg tggctctgtg gaaatcccct tctccttcta ttacccctgg      120

gagttagcca tagttcccaa cgtgagaata tcctggagac ggggccactt ccacgggcag      180

tccttctaca gcacaaggcc gccttccatt cacaaggatt atgtgaaccg gctctttctg      240

aactggacag agggtcagga gagcggcttc ctcaggatct caaacctgcg gaaggaggac      300

cagtctgtgt atttctgccg agtcgagctg gacacccgga gatcagggag gcagcagttg      360

cagtccatca aggggaccaa actcaccatc acccaggctg tcacaaccac caccacctgg      420

aggcccagca gcacaaccac catagccggc ctcagggtca cagaaagcaa agggcactca      480

gaatcatggc acctaagtct ggacactgcc atcagg                                516


<210>  4177
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  4177
ttacactgtg aaatatgtac agcggctgga agtagatgtc atggtcaaat gaagacatgc       60

agttccgaca aagatacttg cgttcttcta gtgggcaaag caacttccaa gggcaaggaa      120

ttagtccaca cctataaagg atgtataagg agtcaggatt gttatagcgg ggtcatttca      180

actacaatgg gccccaaaga ccacatggta acctcatctt tttgttgtca gtcagacggt      240

tgcaactccg ctttcctgtc cgttccgttg accaatctaa ccgagaacgg actgatgtgt      300

ccagcctgta cggcgtcctt ccgtgacaaa tgcatgggac caatgacaca ctgcaccggc      360

aaggagaacc actgcgtcag cctatcagga cacgttcaag ccgggatttt caagcctagg      420

ttcgccatga ggggatgtgc tacagagtca atgtgcttta caaagcccgg ggctgaagta      480

cccaccggaa caaacgtgct attcttacac cacattgaat gtacgcactc acca            534


<210>  4178
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  4178
caggacaaca ctcggaagat cataataaag aattttgaca ttcccaagtc agtacgtcca       60

aatgacgaag tcactgcagt gcttgcagtt caaacagaat tgaaagaatg catggtggtt      120

aaaacttacc tcattagcag catccctcta caaggtgcat ttaactataa gtatactgcc      180

tgcctatgtg acgacaatcc aaaaaccttc tactgggact tttacaccaa cagaactgtg      240

caaattgcag ccgtcgttga tgttattcgg gaattaggca tctgccctga tgatgctgct      300

gtaatcccca tcaaaaacaa ccggttttat actattgaaa tcctaaaggt agaa            354


<210>  4179
<211>  1068
<212>  DNA
<213>  Homo Sapiens

<400>  4179
gtgtccggcg cgcagtacat gggctcaggc tacaccaagg ccgtgtaccg ggtccgcctg       60

cccggcggtg ccgcggtggc gctcaaggcg gtggacttta gcggccacga tctgggcagc      120

tgcgtgcgcg agttcggggt acggaggggc tgctatcggc tggcggccca caagctgctt      180

aaggagatgg tgctgctgga gcggctgcgg caccccaacg tgctgcagct ctatggctac      240

tgctaccagg acagcgagga catcccagac accctgacca ccatcacgga gctgggcgcc      300

cctgtagaaa tgatccagct gctgcaaact tcctgggagg atcgattccg aatctgcctg      360

agcctgggcc gcctcctcca ccacctggcc cactccccac tgggctccgt cactctgctg      420

gacttccgcc ctcggcagtt tgtgctggtg gatggggagc tcaaagtgac ggacctggat      480

gacgcacgtg tggaggagac gccgtgtgca ggcagcaccg actgcatact cgagtttccg      540

gccaggaact tcaccctgcc ctgctcagcc cagggctggt gcgagggcat gaacgagaag      600

cggaacctct ataatgccta caggtttttc ttcacatacc tcctgcctca cagtgccccg      660

ccttcactgc gtcctctgct ggacagcatc gtcaacgcca caggagagct cgcctggggg      720

gtggacgaga ccctggccca gctggagaag gtgctgcacc tgtaccggag cgggcagtat      780

ctgcagaact ccacggcaag cagcagtacc gagtaccagt gtatcccaga cagcaccatc      840

ccccaggaag actaccgctg ctggccatcc taccaccacg ggagctgcct cctttcagtg      900

ttcaacctgg ctgaggctgt ggatgtctgt gagagccatg cccagtgtcg ggcctttgtg      960

gtcaccaacc agaccacctg gacaggtcgg cagctggtct ttttcaagac tggatggagc     1020

caagtggtcc ctgatcccaa caagaccaca tatgtgaagg cctctggc                  1068


<210>  4180
<211>  1581
<212>  DNA
<213>  Homo Sapiens

<400>  4180
tcttaccaag tgatctgcag agatgaaaaa acgcagatga tataccagca acatcagtca       60

tggctgcgcc ctgtgctcag aagcaaccgg gtggaatatt gctggtgcaa cagtggcagg      120

gcacagtgcc actcagtgcc tgtcaaaagt tgcagcgagc caaggtgttt caacgggggc      180

acctgccagc aggccctgta cttctcagat ttcgtgtgcc agtgccccga aggatttgct      240

gggaagtgct gtgaaataga taccagggcc acgtgctacg aggaccaggg catcagctac      300

aggggcacgt ggagcacagc ggagagtggc gccgagtgca ccaactggaa cagcagcgcg      360

ttggcccaga agccctacag cgggcggagg ccagatgcca tcaggctggg cctggggaac      420

cacaactact gcagaaaccc agatcgagac tcaaagccct ggtgctacgt ctttaaggcg      480

gggaagtaca gctcagagtt ctgcagcacc cctgcctgct ctgagggaaa cagtgactgc      540

tactttggga atgggtcagc ctaccgtggc acgcacagcc tcaccgagtc gggtgcctcc      600

tgcctcccgt ggaattccat gatcctgata ggcaaggttt acacagcaca gaaccccagt      660

gcccaggcac tgggcctggg caaacataat tactgccgga atcctgatgg ggatgccaag      720

ccctggtgcc acgtgctgaa gaaccgcagg ctgacgtggg agtactgtga tgtgccctcc      780

tgctccacct gcggcctgag acagtacagc cagcctcagt ttcgcatcaa aggagggctc      840

ttcgccgaca tcgcctccca cccctggcag gctgccatct ttgccaagca caggaggtcg      900

cccggagagc ggttcctgtg cgggggcata ctcatcagct cctgctggat tctctctgcc      960

gcccactgct tccaggagag gtttccgccc caccacctga cggtgatctt gggcagaaca     1020

taccgggtgg tccctggcga ggaggagcag aaatttgaag tcgaaaaata cattgtccat     1080

aaggaattcg atgatgacac ttacgacaat gacattgcgc tgctgcagct gaaatcggat     1140

tcgtcccgct gtgcccagga gagcagcgtg gtccgcactg tgtgccttcc cccggcggac     1200

ctgcagctgc cggactggac ggagtgtgag ctctccggct acggcaagca tgaggccttg     1260

tctcctttct attcggagcg gctgaaggag gctcatgtca gactgtaccc atccagccgc     1320

tgcacatcac aacatttact taacagaaca gtcaccgaca acatgctgtg tgctggagac     1380

actcggagcg gcgggcccca ggcaaacttg cacgacgcct gccagggcga ttcgggaggc     1440

cccctggtgt gtctgaacga tggccgcatg actttggtgg gcatcatcag ctggggcctg     1500

ggctgtggac agaaggatgt cccgggtgtg tacaccaagg ttaccaacta cctagactgg     1560

attcgtgaca acatgcgacc g                                               1581


<210>  4181
<211>  1233
<212>  DNA
<213>  Homo Sapiens

<400>  4181
agcaatgaac ttcatcaagt tccatcgaac tgtgactgtc taaatggagg aacatgtgtg       60

tccaacaagt acttctccaa cattcactgg tgcaactgcc caaagaaatt cggagggcag      120

cactgtgaaa tagataagtc aaaaacctgc tatgagggga atggtcactt ttaccgagga      180

aaggccagca ctgacaccat gggccggccc tgcctgccct ggaactctgc cactgtcctt      240

cagcaaacgt accatgccca cagatctgat gctcttcagc tgggcctggg gaaacataat      300

tactgcagga acccagacaa ccggaggcga ccctggtgct atgtgcaggt gggcctaaag      360

ccgcttgtcc aagagtgcat ggtgcatgac tgcgcagatg gaaaaaagcc ctcctctcct      420

ccagaagaat taaaatttca gtgtggccaa aagactctga ggccccgctt taagattatt      480

gggggagaat tcaccaccat cgagaaccag ccctggtttg cggccatcta caggaggcac      540

cgggggggct ctgtcaccta cgtgtgtgga ggcagcctca tcagcccttg ctgggtgatc      600

agcgccacac actgcttcat tgattaccca aagaaggagg actacatcgt ctacctgggt      660

cgctcaaggc ttaactccaa cacgcaaggg gagatgaagt ttgaggtgga aaacctcatc      720

ctacacaagg actacagcgc tgacacgctt gctcaccaca acgacattgc cttgctgaag      780

atccgttcca aggagggcag gtgtgcgcag ccatcccgga ctatacagac catctgcctg      840

ccctcgatgt ataacgatcc ccagtttggc acaagctgtg agatcactgg ctttggaaaa      900

gagaattcta ccgactatct ctatccggag cagctgaaaa tgactgttgt gaagctgatt      960

tcccaccggg agtgtcagca gccccactac tacggctctg aagtcaccac caaaatgctg     1020

tgtgctgctg acccacagtg gaaaacagat tcctgccagg gagactcagg gggacccctc     1080

gtctgttccc tccaaggccg catgactttg actggaattg tgagctgggg ccgtggatgt     1140

gccctgaagg acaagccagg cgtctacacg agagtctcac acttcttacc ctggatccgc     1200

agtcacacca aggaagagaa tggcctggcc ctc                                  1233


<210>  4182
<211>  849
<212>  DNA
<213>  Homo Sapiens

<400>  4182
ctgcggtgca tgcagtgtaa gaccaacggg gattgccgtg tggaagagtg cgccctggga       60

caggacctct gcaggaccac gatcgtgcgc ttgtgggaag aaggagaaga gctggagctg      120

gtggagaaaa gctgtaccca ctcagagaag accaacagga ccctgagcta tcggactggc      180

ttgaagatca ccagccttac cgaggttgtg tgtgggttag acttgtgcaa ccagggcaac      240

tctggccggg ctgtcaccta ttcccgaagc cgttacctcg aatgcatttc ctgtggctca      300

tcagacatga gctgtgagag gggccggcac cagagcctgc agtgccgcag ccctgaagaa      360

cagtgcctgg atgtggtgac ccactggatc caggaaggtg aagaagggcg tccaaaggat      420

gaccgccacc tccgtggctg tggctacctt cccggctgcc cgggctccaa tggtttccac      480

aacaacgaca ccttccactt cctgaaatgc tgcaacacca ccaaatgcaa cgagggccca      540

atcctggagc ttgaaaatct gccgcagaat ggccgccagt gttacagctg caaggggaac      600

agcacccatg gatgctcctc tgaagagact ttcctcattg actgccgagg ccccatgaat      660

caatgtctgg tagccaccgg cactcacgaa ccgaaaaacc aaagctatat ggtaagaggc      720

tgtgcaaccg cctcaatgtg ccaacatgcc cacctgggtg acgccttcag catgaaccac      780

attgatgtct cctgctgtac taaaagtggc tgtaaccacc cagacctgga tgtccagtac      840

cgcagtggg                                                              849


<210>  4183
<211>  1497
<212>  DNA
<213>  Homo Sapiens

<400>  4183
actttgctca cccggcagcc agccccgctg tcccagaagc agcggtcatt tgtcacattc       60

cgaggagagc ccgccgaggg tttcaatcac ctggtggtgg atgagaggac aggacacatt      120

tacttggggg ccgtcaatcg gatttacaag ctctccagcg acctgaaggt cttggtgacg      180

catgagacag ggccggacga ggacaacccc aagtgttacc caccccgcat cgtccagacc      240

tgcaatgagc ccctgaccac caccaacaat gtcaacaaga tgctcctcat agactacaag      300

gagaacaggc tgattgcctg tgggagcctg taccaaggca tctgcaagct gctgaggctg      360

gaggacctct tcaagctggg ggagccttat cataagaagg agcactatct gtcaggtgtc      420

aacgagagcg gctcagtctt tggagtgatc gtctcctaca gcaacctgga tgacaagctg      480

ttcattgcca cggcagtgga tgggaagccc gagtattttc ccaccatctc cagccggaaa      540

ctgaccaaga actctgaggc ggatggcatg ttcgcgtacg tcttccatga tgagttcgtg      600

gcctcgatga ttaagatccc ttcggacacc ttcaccatca tccctgactt tgatatctac      660

tatgtctatg gttttagcag tggcaacttt gtctactttt tgaccctcca acctgagatg      720

gtgtctccac caggctccac caccaaggag caggtgtata catccaagct cgtgaggctt      780

tgcaaggagg acacagcctt caactcctat gtagaggtgc ccattggctg tgagcgcagt      840

ggggtggagt accgcctgct gcaggctgcc tacctgtcca aagcgggggc cgtgcttggc      900

aggacccttg gagtccatcc agatgatgac ctgctcttca ccgtcttctc caagggccag      960

aagcggaaaa tgaaatccct ggatgagtcg gccctgtgca tcttcatctt gaagcagata     1020

aatgaccgca ttaaggagcg gctgcagtct tgttaccggg gcgagggcac gctggacctg     1080

gcctggctca aggtgaagga catcccctgc agcagtgcgc tcttaaccat tgacgataac     1140

ttctgtggcc tggacatgaa tgctcccctg ggagtgtccg acatggtgcg tggaattccc     1200

gtcttcacgg aggacaggga ccgcatgacg tctgtcatcg catatgtcta caagaaccac     1260

tctctggcct ttgtgggcac caaaagtggc aagctgaaga agtccttcgg cacaggtcca     1320

caaggcggaa tcacccagga gtggattgga gtggcgggag acccacctgg ggcgaacatt     1380

gcttctcagg aacagatgct gtgtgtgtat cttcagtgct caagtcacaa agcaatatca     1440

gatcagagag tccagcctct gctttgttgc ttcctaaatg tacctgggaa ttcttcc        1497


<210>  4184
<211>  1782
<212>  DNA
<213>  Homo Sapiens

<400>  4184
ggacctgtgc ttgccgtgag ggccccagga tttggccgaa gtggcggcca cagcctgagc       60

cccgaagaga acgaatttgc ggaggaggag ccggtgctgg tactgagccc tgaggagccc      120

gggcctggcc cagccgcggt cagctgcccc cgagactgtg cctgttccca ggagggcgtc      180

gtggactgtg gcggtattga cctgcgtgag ttcccggggg acctgcctga gcacaccaac      240

cacctatctc tgcagaacaa ccagctggaa aagatctacc ctgaggagct ctcccggctg      300

caccggctgg agacactgaa cctgcaaaac aaccgcctga cttcccgagg gctcccagag      360

aaggcgtttg agcatctgac caacctcaat tacctgtact tggccaataa caagctgacc      420

ttggcacccc gcttcctgcc aaacgccctg atcagtgtgg actttgctgc caactatctc      480

accaagatct atgggctcac ctttggccag aagccaaact tgaggtctgt gtacctgcac      540

aacaacaagc tggcagacgc cgggctgccg gacaacatgt tcaacggctc cagcaacgtc      600

gaggtcctca tcctgtccag caacttcctg cgccacgtgc ccaagcacct gccgcctgcc      660

ctgtacaagc tgcacctcaa gaacaacaag ctggagaaga tccccccggg ggccttcagc      720

gagctgagca gcctgcgcga gctatacctg cagaacaact acctgactga cgagggcctg      780

gacaacgaga ccttctggaa gctctccagc ctggagtacc tggatctgtc cagcaacaac      840

ctgtctcggg tcccagctgg gctgccgcgc agcctggtgc tgctgcactt ggagaagaac      900

gccatccgga gcgtggacgc gaatgtgctg acccccatcc gcagcctgga gtacctgctg      960

ctgcacagca accagctgcg ggagcagggc atccacccac tggccttcca gggcctcaag     1020

cggttgcaca cggtgcacct gtacaacaac gcgctggagc gcgtgcccag tggcctgcct     1080

cgccgcgtgc gcaccctcat gatcctgcac aaccagatca caggcattgg ccgcgaagac     1140

tttgccacca cctacttcct ggaggagctc aacctcagct acaaccgcat caccagccca     1200

caggtgcacc gcgacgcctt ccgcaagctg cgcctgctgc gctcgctgga cctgtcgggc     1260

aaccggctgc acacgctgcc acctgggctg cctcgaaatg tccatgtgct gaaggtcaag     1320

cgcaatgagc tggctgcctt ggcacgaggg gcgctggcgg gcatggctca gctgcgtgag     1380

ctgtacctca ccagcaaccg actgcgcagc cgagccctgg gcccccgtgc ctgggtggac     1440

ctcgcccatc tgcagctgct ggacatcgcc gggaatcagc tcacagagat ccccgagggg     1500

ctccccgagt cacttgagta cctgtacctg cagaacaaca agattagtgc ggtgcccgcc     1560

aatgccttcg actccacgcc caacctcaag gggatctttc tcaggtttaa caagctggct     1620

gtgggctccg tggtggacag tgccttccgg aggctgaagc acctgcaggt cttggacatt     1680

gaaggcaact tagagtttgg tgacatttcc aaggaccgtg gccgcttggg gaaggaaaag     1740

gaggaggagg aagaggagga ggaggaggaa gaggaaacaa ga                        1782


<210>  4185
<211>  1458
<212>  DNA
<213>  Homo Sapiens

<400>  4185
ttggaagacg ctgccttccc ccacctgggg gagagcttgc agcccctgct ccgggcctgt       60

cccctgcgct gctcctgccc ccgagtcgac actgtggact gtgatggctt ggaccttcga      120

gtgttcccgg acaacatcac cagagccgct cagcacctct ccctgcagaa caaccagctc      180

caggaactcc cctacaatga gctgtcccgc ctcagtggcc tgcgaaccct caacctccac      240

aacaacctca tctcctccga aggcctgcct gacgaggcct tcgagtccct cacccagctg      300

cagcacctct gcgtggctca caacaagctc tcagtggccc ctcagtttct gccccggtcc      360

ctccgtgtcg cggatctggc tgccaaccaa gtgatggaga tcttccccct cacctttggg      420

gagaagccgg cactcaggtc cgtgtacctc cacaacaacc agctgagcaa cgctggcctg      480

ccccccgacg ccttccgcgg ctccgaggcc atcgccaccc tcagcctctc caacaaccag      540

ctcagctacc tgccgcccag cctgccgccc tcactcgagc ggctccacct gcagaacaat      600

ctcatctcca aggtgccccg aggagccctg agccgccaga ctcaactccg tgagctctac      660

ctccagcaca accagctgac agacagtggc ctggatgcca ccaccttcag caagctgcat      720

agccttgaat acctggatct ctcccacaac cagctgacca cagtgcccgc cggcctgccc      780

cggaccctgg ctatcctgca cctgggccgc aaccgcatcc ggcaggtgga ggcggctcgg      840

ctgcacgggg cgcgtggtct gcgctatttg ttgctgcagc acaaccagct ggggagctca      900

gggctgcccg ccggggctct gcggccgctg cggggcctgc acacgctgca cctctatggc      960

aatgggctgg accgcgtgcc tccagccctg ccccgccgcc tgcgtgccct ggtgctgccc     1020

cacaaccacg tggccgcgct gggtgcccgt gacctggtcg ccacaccggg cctgacggag     1080

cttaacctgg cctataaccg cctggccagc gcccgtgtgc accaccgggc cttccgccgg     1140

ctgcgtgccc tgcgcagcct cgacctggca gggaatcagc taacccggct gcccatgggc     1200

ctgcccactg gcctgcgcac cctgcagctg caacgcaacc agctgcggat gctcgagccc     1260

gagcctctgg ccggcctgga ccaactgcgg gagctcagcc tggcgcacaa ccggctccgg     1320

gtcggcgaca tcgggccagg cacctggcat gagctccaag ccctccaggt caggcacagg     1380

ctggttagcc acactgtccc cagggcccct ccatccccct gcctgccctg ccacgtccca     1440

aacattctag ttagctgg                                                   1458


<210>  4186
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  4186
gctgaactcc gctgcatgtg tataaagaca acctctggaa ttcatcccaa aaacatccaa       60

agtttggaag tgatcgggaa aggaacccat tgcaaccaag tcgaagtgat agccacactg      120

aaggatggga ggaaaatctg cctggaccca gatgctccca gaatcaagaa aattgtacag      180

aaaaaattgg caggtgatga atctgctgat                                       210


<210>  4187
<211>  804
<212>  DNA
<213>  Homo Sapiens

<400>  4187
gccaagggtg gatccctcag agagagtcag ggagtctgct ccaagcagac actggtggtc       60

ccgctccact acaacgagtc ctacagccaa ccagtgtaca agccctacct gaccttgtgc      120

gctgggaggc gcatctgcag cacttacagg accatgtacc gcgttatgtg gcgggaggtg      180

aggcgggagg ttcagcagac ccatgcagtg tgctgccagg gctggaagaa gcggcacccg      240

ggggcgctca cctgtgaagc catctgcgcc aagccttgcc tgaacggagg cgtctgcgtt      300

aggcctgacc agtgcgagtg cgcccccggc tggggaggga agcactgtca tgtggacgtg      360

gatgaatgta ggaccagcat caccctctgc tcgcaccatt gttttaatac ggcaggcagc      420

ttcacctgcg gctgccccca tgacctagtg ctaggcgtgg acgggcgcac ctgcatggag      480

gggtccccag agcccccaac cagtgccagc atactcagcg tggccgttcg ggaggcggaa      540

aaagatgagc gcgctctgaa gcaggagatt cacgagctgc gagggcgcct ggagcggctg      600

gagcagtggg ccggtcaggc tggggcctgg gtcagagcgg tgctgcccgt gccgcctgaa      660

gagctgcagc cagaacaggt ggctgagctg tggggccggg gtgaccggat cgaatctctc      720

agcgaccagg tgctgctgct ggaggagagg ctaggtgcct gctcctgtga ggacaacagc      780

ctgggcctcg gcgtcaatca tcga                                             804


<210>  4188
<211>  1086
<212>  DNA
<213>  Homo Sapiens

<400>  4188
cagccaacaa gacgaccaag acccgggact gggcccgggc gcagacccag gcccaggccc       60

aggcccacac ccagctttcc tcagcctgat gaaccagcag agccaacaga cctgcctcct      120

cccctccctc caggccctcc atctatcttc cctgactgtc cccgcgaatg ctactgcccc      180

cctgatttcc catctgccct ctactgtgat agccgcaacc tgcgaaaggt ccctgtcatc      240

ccgccccgca tccattacct ctatctccag aacaacttca tcactgagct cccggtggag      300

tccttccaga atgccacagg cctgcgatgg attaacctgg acaacaaccg aatccgcaag      360

atagaccaga gggtgctgga gaaactgccc ggcctggtgt tcctctacat ggagaagaac      420

cagttggaag aggtcccctc ggccctgccc cggaacctgg agcagctgag gctgagccag      480

aaccacatct ccagaatccc gcctggtgtc ttcagcaagc tggagaacct gctgctcctg      540

gatctccagc acaacaggct gagcgacggc gtcttcaagc ccgacacctt ccatggcctc      600

aagaacctca tgcagctcaa cctggcccac aacatcctga gaaagatgcc gcccagggtc      660

cccaccgcca ttcaccagct ctacctggac agtaacaaga ttgagaccat ccctaacgga      720

tacttcaaga gctttcccaa tcttgccttc attcggctta actacaacaa gctgacagac      780

aggggactcc ccaagaactc ctttaatatc tccaacctgc ttgtgctcca cctgtcccac      840

aacaggatca gcagtgtgcc cgccatcaac aacaggctgg aacacctgta cctcaacaac      900

aatagcatcg agaaaatcaa cggaacccag atttgcccca acgacctagt ggcgttccat      960

gacttctcct cggacctgga gaacgtgcca cacctgcgct acctgcggct ggatggaaac     1020

tacttgaagc cgcccatccc gctggacctc atgatgtgct tccgcctcct gcagtccgtg     1080

gtcatc                                                                1086


<210>  4189
<211>  1602
<212>  DNA
<213>  Homo Sapiens

<400>  4189
ccgtgccaca cagccgcacg ctcagagtgc aagcgcagcc acaagttcgt gcctggtgca       60

tggctggccg gggagggtgt ggacgtgacc agcctccgcc gctcgggctc cttcccagtg      120

gacacacaaa ggttcctgcg gcccgacggc acctgcaccc tctgtgaaaa tgccctacag      180

gagggcaccc tccagcgcct gcctctggcg ctcaccaact ggcgggccca gggctctggc      240

tgccagcgcc atgtaaccag ggccaaagtc agctccactg aagctgtggc ccgggatgcg      300

gctcgtagca tccgcaacga ctggaaggtc gggctggacg tgactcctaa gcccaccagc      360

aatgtgcatg tgtctgtggc cggctcacac tcacaggcag ccaactttgc agcccagaag      420

acccaccagg accagtacag cttcagcact gacacggtgg agtgccgctt ctacagtttc      480

catgtggtac acactccccc gctgcaccct gacttcaaga gggccctcgg ggacctgccc      540

caccacttca acgcctccac ccagcccgcc tacctcaggc ttatctccaa ctacggcacc      600

cacttcatcc gggctgtgga gctgggtggc cgcatatcgg ccctcactgc cctgcgcacc      660

tgcgagctgg ccctggaagg gctcacggac aacgaggtgg aggactgcct gactgtcgag      720

gcccaggtca acataggcat ccacggcagc atctctgccg aagccaaggc ctgtgaggag      780

aagaagaaga agcacaagat gacggcctcc ttccaccaaa cctaccggga gcgccattcg      840

gaagtggttg gcggccatca cacctccatt aacgacctgc tgttcgggat ccaggccggg      900

cccgagcagt actcagcctg ggtaaactcg ctgcccggca gccctggcct ggtggactac      960

accctggaac ccctgcacgt gctgctggac agccaggacc cgcggcggga ggcactgagg     1020

agggccctga gtcagtacct gacggacagg gctcgctgga gggactgcag ccggccgtgc     1080

ccaccagggc ggcagaagag cccccgagac ccatgccagt gtgtgtgcca tggctcagcg     1140

gtcaccaccc aggactgctg ccctcggcag aggggcctgg cccagctgga ggtgaccttc     1200

atccaagcat ggggcctgtg gggggactgg ttcactgcca cggatgccta tgtgaagctc     1260

ttctttggtg gccaggagct gaggacgagc accgtgtggg acaataacaa ccccatctgg     1320

tcagtgcggc tggattttgg ggatgtgctc ctggccacag gggggcccct gaggttgcag     1380

gtctgggatc aggactctgg cagggacgat gacctccttg gcacctgtga tcaggctccc     1440

aagtctggtt cccatgaggt gagatgcaac ctgaatcatg gccacctaaa attccgctat     1500

catgccaggt gcttgcccca cctgggagga ggcacctgcc tggactatgt cccccaaatg     1560

cttctggggg agcctccagg aaaccggagt ggggccgtgt gg                        1602


<210>  4190
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4190
acctgccgct acctcctggt gagaagtctt cagacgttta gtcaagcttg gtttacttgc       60

cggaggtgct acaggggcaa cctggtttcc atccacaact tcaatattaa ttatcgaatc      120

cagtgttctg tcagcgcgct caaccagggt caagtctgga ttggaggcag gatcacaggc      180

tcgggtcgct gcagacgctt tcagtgggtt gacggcagcc gctggaactt tgcgtactgg      240

gctgctcacc agccctggtc ccgcggtggt cactgcgtgg ccctgtgtac ccgaggaggc      300

tactggcgtc gagcccactg cctcagaaga cttcctttca tctgttccta c               351


<210>  4191
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  4191
cttcatctgg agaatgatgc cccccatctg gagagcctag agacacaggc agacctaggc       60

caggatctgg atagttcaaa ggagcaggag agagacttgg ctctgacgga ggaggtgatt      120

caggcagagg gagaggaggt caaggcttct gcctgtcaag acaactttga ggatgaggaa      180

gccatggagt cggacccagc tgccttagac aaggacttcc agtgccccag ggaagaagac      240

attgttgaag tgcagggaag tccaaggtgc aagacctgcc gctacctatt ggtgcggact      300

cctaaaactt ttgcagaagc tcagaatgtc tgcagcagat gctacggagg caaccttgtc      360

tctatccatg acttcaactt caactatcgc attcagtgct gcactagcac agtcaaccaa      420

gcccaggtct ggattggagg caacctcagg ggctggttcc tgtggaagcg gttttgctgg      480

actgatggga gccactggaa ttttgcttac tggtccccag ggcaacctgg gaatgggcaa      540

ggctcctgtg tggccctatg caccaaagga ggttattggc gacgagctca atgcgacaag      600

caactgccct tcgtctgctc cttc                                             624


<210>  4192
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  4192
cagttacctc ctggaaaacc tgagatcttt aaatgtcgtt ctcccaataa ggaaacattc       60

acctgctggt ggaggcctgg gacagatgga ggacttccta ccaattattc actgacttac      120

cacagggaag gagagacact catgcatgaa tgtccagact acataaccgg tggccccaac      180

tcctgccact ttggcaagca gtacacctcc atgtggagga catacatcat gatggtcaat      240

gccactaacc agatgggaag cagtttctcg gatgaacttt atgtggacgt gacttacata      300

gttcagccag accctccttt ggagctggct gtggaagtaa aacagccaga agacagaaaa      360

ccctacctgt ggattaaatg gtctccacct accctgattg acttaaaaac tggttggttc      420

acgctcctgt atgaaattcg attaaaaccc gagaaagcag ctgagtggga gatccatttt      480

gctgggcagc aaacagagtt taagattctc agcctacatc caggacagaa ataccttgtc      540

caggttcgct gcaaaccaga ccatggatac tggagtgcat ggagtccagc gaccttcatt      600

cagataccta gtgacttcac catgaatgat                                       630


<210>  4193
<211>  1257
<212>  DNA
<213>  Homo Sapiens

<400>  4193
gccaactcct tcctggagga gctccgtcac agcagcctgg agcgggagtg catagaggag       60

atctgtgact tcgaggaggc caaggaaatt ttccaaaatg tggatgacac actggccttc      120

tggtccaagc acgtcgacgg tgaccagtgc ttggtcttgc ccttggagca cccgtgcgcc      180

agcctgtgct gcgggcacgg cacgtgcatc gacggcatcg gcagcttcag ctgcgactgc      240

cgcagcggct gggagggccg cttctgccag cgcgaggtga gcttcctcaa ttgctctctg      300

gacaacggcg gctgcacgca ttactgccta gaggaggtgg gctggcggcg ctgtagctgt      360

gcgcctggct acaagctggg ggacgacctc ctgcagtgtc accccgcagt gaagttccct      420

tgtgggaggc cctggaagcg gatggagaag aagcgcagtc acctgaaacg agacacagaa      480

gaccaagaag accaagtaga tccgcggctc attgatggga agatgaccag gcggggagac      540

agcccctggc aggtggtcct gctggactca aagaagaagc tggcctgcgg ggcagtgctc      600

atccacccct cctgggtgct gacagcggcc cactgcatgg atgagtccaa gaagctcctt      660

gtcaggcttg gagagtatga cctgcggcgc tgggagaagt gggagctgga cctggacatc      720

aaggaggtct tcgtccaccc caactacagc aagagcacca ccgacaatga catcgcactg      780

ctgcacctgg cccagcccgc caccctctcg cagaccatag tgcccatctg cctcccggac      840

agcggccttg cagagcgcga gctcaatcag gccggccagg agaccctcgt gacgggctgg      900

ggctaccaca gcagccgaga gaaggaggcc aagagaaacc gcaccttcgt cctcaacttc      960

atcaagattc ccgtggtccc gcacaatgag tgcagcgagg tcatgagcaa catggtgtct     1020

gagaacatgc tgtgtgcggg catcctcggg gaccggcagg atgcctgcga gggcgacagt     1080

ggggggccca tggtcgcctc cttccacggc acctggttcc tggtgggcct ggtgagctgg     1140

ggtgagggct gtgggctcct tcacaactac ggcgtttaca ccaaagtcag ccgctacctc     1200

gactggatcc atgggcacat cagagacaag gaagcccccc agaagagctg ggcacct        1257


<210>  4194
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  4194
agccaagacg cctcagatgg cctccaaaga cttcatatgc tccagatctc ctacttccgc       60

gacccctatc acgtgtggta ccagggcaac gcgtcgctgg ggggacacct aacgcacgtg      120

ctggaaggcc cagacaccaa caccacgatc attcagctgc agcccttgca ggagcccgag      180

agctgggcgc gcacgcagag tggcctgcag tcctacctgc tccagttcca cggcctcgtg      240

cgcctggtgc accaggagcg gaccttggcc tttcctctga ccatccgctg cttcctgggc      300

tgtgagctgc ctcccgaggg ctctagagcc catgtcttct tcgaagtggc tgtgaatggg      360

agctcctttg tgagtttccg gccggagaga gccttgtggc aggcagacac ccaggtcacc      420

tccggagtgg tcaccttcac cctgcagcag ctcaatgcct acaaccgcac tcggtatgaa      480

ctgcgggaat tcctggagga cacctgtgtg cagtatgtgc agaaacatat ttccgcggaa      540

aacacgaaag ggagccaaac aagccgctcc tacacttcg                             579


<210>  4195
<211>  1905
<212>  DNA
<213>  Homo Sapiens

<400>  4195
gcaaattctt tacttgaaga aaccaaacag ggtaatcttg aaagagaatg catcgaagaa       60

ctgtgcaata aagaagaagc cagggaggtc tttgaaaatg acccggaaac ggattatttt      120

tatccaaaat acttagtttg tcttcgctct tttcaaactg ggttattcac tgctgcacgt      180

cagtcaacta atgcttatcc tgacctaaga agctgtgtca atgccattcc agaccagtgt      240

agtcctctgc catgcaatga agatggatat atgagctgca aagatggaaa agcttctttt      300

acttgcactt gtaaaccagg ttggcaagga gaaaagtgtg aatttgacat aaatgaatgc      360

aaagatccct caaatataaa tggaggttgc agtcaaattt gtgataatac acctggaagt      420

taccactgtt cctgtaaaaa tggttttgtt atgctttcaa ataagaaaga ttgtaaagat      480

gtggatgaat gctctttgaa gccaagcatt tgtggcacag ctgtgtgcaa gaacatccca      540

ggagattttg aatgtgaatg ccccgaaggc tacagatata atctcaaatc aaagtcttgt      600

gaagatatag atgaatgctc tgagaacatg tgtgctcagc tttgtgtcaa ttaccctgga      660

ggttacactt gctattgtga tgggaagaaa ggattcaaac ttgcccaaga tcagaagagt      720

tgtgaggttg tttcagtgtg ccttcccttg aaccttgaca caaagtatga attactttac      780

ttggcggagc agtttgcagg ggttgtttta tatttaaaat ttcgtttgcc agaaatcagc      840

agattttcag cagaatttga tttccggaca tatgattcag aaggcgtgat actgtacgca      900

gaatctatcg atcactcagc gtggctcctg attgcacttc gtggtggaaa gattgaagtt      960

cagcttaaga atgaacatac atccaaaatc acaactggag gtgatgttat taataatggt     1020

ctatggaata tggtgtctgt ggaagaatta gaacatagta ttagcattaa aatagctaaa     1080

gaagctgtga tggatataaa taaacctgga ccccttttta agccggaaaa tggattgctg     1140

gaaaccaaag tatactttgc aggattccct cggaaagtgg aaagtgaact cattaaaccg     1200

attaaccctc gtctagatgg atgtatacga agctggaatt tgatgaagca aggagcttct     1260

ggaataaagg aaattattca agaaaaacaa aataagcatt gcctggttac tgtggagaag     1320

ggctcctact atcctggttc tggaattgct caatttcaca tagattataa taatgtatcc     1380

agtgctgagg gttggcatgt aaatgtgacc ttgaatattc gtccatccac gggcactggt     1440

gttatgcttg ccttggtttc tggtaacaac acagtgccct ttgctgtgtc cttggtggac     1500

tccacctctg aaaaatcaca ggatattctg ttatctgttg aaaatactgt aatatatcgg     1560

atacaggccc taagtctatg ttccgatcaa caatctcatc tggaatttag agtcaacaga     1620

aacaatctgg agttgtcgac accacttaaa atagaaacca tctcccatga agaccttcaa     1680

agacaacttg ccgtcttgga caaagcaatg aaagcaaaag tggccacata cctgggtggc     1740

cttccagatg ttccattcag tgccacacca gtgaatgcct tttataatgg ctgcatggaa     1800

gtgaatatta atggtgtaca gttggatctg gatgaagcca tttctaaaca taatgatatt     1860

agagctcact catgtccatc agtttggaaa aagacaaaga attct                     1905


<210>  4196
<211>  1080
<212>  DNA
<213>  Homo Sapiens

<400>  4196
gcgggctcct atcttctgga agaactcttc gagggaaact tggaaaaaga atgttatgaa       60

gaaatctgtg tctatgaaga agcaagagaa gtgtttgaaa atgaagtagt cactgatgaa      120

ttctggagac gatataaggg cggctccccg tgcatctccc agccctgcct ccacaacggc      180

tcttgccagg acagcatctg gggctacacc tgcacctgct cccccggcta tgagggcagc      240

aactgcgagc tggctaaaaa tgaatgtcac ccagagcgga ctgatgggtg tcaacacttc      300

tgcctcccag gacaggaatc ctacacgtgc agctgtgctc agggctacag gcttggtgag      360

gaccacaaac agtgtgtgcc ccacgaccag tgtgcctgcg gggtgctgac ctctgagaag      420

cgtgcaccgg atctacagga cctcccgtgg caggtaaagt taacaaattc cgaaggaaaa      480

gacttctgtg gtggtgttat aatacgggaa aattttgtac tgacaacagc aaaatgttca      540

ctgttacaca ggaatattac tgtaaaaaca tattttaaca gaacgagcca agacccgctg      600

atgatcaaga taacgcacgt ccatgtgcac atgcggtatg acgcggacgc gggggagaat      660

gacctgtcac tgctggagct ggagtggccc atccagtgcc caggtgcggg gctccccgtg      720

tgcacccctg agaaagactt cgctgagcac ctcctcatcc cacgcaccag gggcctcctc      780

agcggctggg cacgcaatgg cactgacctg ggcaactcgc tgaccacgcg gcctgtcaca      840

cttgtggagg gggaggagtg cgggcaggtc ctgaatgtga ctgtcaccac caggacctac      900

tgtgagagaa gcagcgtggc ggccatgcac tggatggatg gaagtgtggt caccagagaa      960

cacagaggct cctggtttct cacgggggtc ctgggctcgc agccagtagg agggcaggct     1020

cacatggtcc ttgtcaccaa ggtctccagg tactcactct ggtttaaaca gatcatgaac     1080


<210>  4197
<211>  2742
<212>  DNA
<213>  Homo Sapiens

<400>  4197
tttagcgaac tgtcttttgt aaaagaacca caggatgtaa ctgtcacaag aaaggaccca       60

gtcgttttag attgccaggc tcacggagaa gttcctatta aggtcacatg gttgaaaaat      120

ggagcaaaaa tgtctgaaaa taaacggatc gaggttcttt ctaacggctc tttatacatc      180

agtgaggtgg aaggcaggcg aggagagcag tccgatgaag gattttatca gtgcttggca      240

atgaacaaat atggagccat tcttagtcaa aaagctcatc ttgccttatc aactatttct      300

gcatttgaag tccagccaat ttccactgag gtccacgaag gtggagttgc tcgatttgca      360

tgcaagattt catcccaccc tcctgcagtc ataacatggg agttcaatcg gacaactcta      420

cctatgacta tggacaggat aactgcccta ccaacaggag tattgcagat ctatgatgtc      480

agccaaaggg attctggaaa ttatcgttgt attgctgcca ctgtagccca ccgacgtaaa      540

agtatggagg cctcgctaac tgtgattcca gctaaggagt caaaatcctt ccacacacca      600

acaattatag caggtccaca gaacataaca acatctcttc atcagactgt agttttggaa      660

tgcatggcca caggaaatcc caaaccaatc atttcttgga gccgccttga tcacaaatcc      720

attgatgtct ttaatactcg ggtacttgga aatggtaatc tcatgatatc tgatgtcagg      780

ctacaacatg ctggagtata tgtttgtcgg gccactaccc ctggcacacg caactttaca      840

gttgctatgg caactttaac tgtattagct cctccttcat ttgttgaatg gccagaaagt      900

ttaacaaggc ctcgagctgg cactgctcga tttgtgtgtc aggcagaagg aatcccctct      960

cccaagatgt catggttgaa aaatggaagg aagatacatt cgaatggtag aattaaaatg     1020

tacaacagta aattggtaat taaccagatt attcctgaag atgatgctat ttatcagtgc     1080

atggctgaga atagccaagg atctatttta tctagagcca gactgactgt agtgatgtca     1140

gaagacagac ccagtgctcc ctataatgta catgctgaaa ccatgtcaag ctcagccatt     1200

cttttagcct gggagaggcc actttataat tcagacaaag tcattgccta ttctgtacac     1260

tacatgaaag cagaaggttt aaataatgaa gagtatcaag tagtcatcgg aaatgacaca     1320

actcattata ttattgatga cttagagcct gccagcaatt atactttcta cattgtagca     1380

tatatgccaa tgggagccag ccagatgtct gaccatgtga cacagaatac tctagaggat     1440

gttcccctga gacctcctga aattagtttg acaagtcgaa gtcccactga tattctcatc     1500

tcctggctgc caatcccagc caaatatcgg cggggccaag tggtgctgta tcgcttgtct     1560

ttccgcctaa gtactgagaa ttcaatccaa gttctggagc tcccggggac cacgcatgag     1620

taccttttgg aaggcctgaa acctgacagt gtctacctgg ttcggattac tgctgccacc     1680

agagtggggc tgggagagtc atcagtatgg acttcacata ggacgcccaa agctacaagc     1740

gtgaaagccc ctaagtctcc agagttgcat ttggagcctc tgaactgtac caccatttct     1800

gtgaggtggc agcaagatgt agaggacaca gctgctattc agggctacaa gctgtactac     1860

aaggaagaag ggcagcagga gaatgggccc attttcttgg ataccaagga cctactctat     1920

actctcagtg gcttagaccc cagaagaaaa tatcatgtga gactcctggc ttacaacaac     1980

atagacgatg gctatcaggc agatcagact gtcagcactc caggatgcgt gtctgttcgt     2040

gatcgcatgg tccctcctcc accaccaccc caccatctct atgcgaaggc taacacctca     2100

tcttccatct tcctgcactg gaggaggcct gcattcaccg ctgcacaaat cattaactac     2160

accatccgct gtaatcctgt tggcctgcag aatgcttctt tggttctgta ccttcaaaca     2220

tcagaaactc acatgttggt tcaaggtcta gaaccaaaca ccaaatacga atttgccgtt     2280

cgattacatg tggatcagct ttccagtcct tggagccctg tagtctacca ttctactctt     2340

ccagaagcac cagcaggccc accagttgga gtaaaagtga cattaataga ggatgacact     2400

gccctggttt cttggaaacc ccctgatggc ccagaaacag ttgtgacccg ctatactatc     2460

ttatatgcat ctaggaaggc ctggattgca ggagagtggc aggtcttaca ccgtgaaggg     2520

gcaataacca tggctttgct agaaaacttg gtagcaggaa atgtgtacat tgtcaagata     2580

tctgcatcca atgaggtggg agaaggaccc ttttcaaatt ctgtggagct ggcagtactt     2640

ccaaaggaaa cctctgaatc aaatcagagg cccaagcgtt tagattctgc tgatgccaaa     2700

gtttattcag gatattacca tctggaccaa aaatcaatga ct                        2742


<210>  4198
<211>  1161
<212>  DNA
<213>  Homo Sapiens

<400>  4198
ctgctctgcc agtttgggac agttcagcat gtgtggaagg tgtccgacct gccccggcaa       60

tggaccccta agaacaccag ctgcgacagc ggcttggggt gccaggacac gttgatgctc      120

attgagagcg gaccccaagt gagcctggtg ctctccaagg gctgcacgga ggccaaggac      180

caggagcccc gcgtcactga gcaccggatg ggccccggcc tctccctgat ctcctacacc      240

ttcgtgtgcc gccaggagga cttctgcaac aacctcgtta actccctccc gctttgggcc      300

ccacagcccc cagcagaccc aggatccttg aggtgcccag tctgcttgtc tatggaaggc      360

tgtctggagg ggacaacaga agagatctgc cccaagggga ccacacactg ttatgatggc      420

ctcctcaggc tcaggggagg aggcatcttc tccaatctga gagtccaggg atgcatgccc      480

cagccaggtt gcaacctgct caatgggaca caggaaattg ggcccgtggg tatgactgag      540

aactgcaata ggaaagattt tctgacctgt catcggggga ccaccattat gacacacgga      600

aacttggctc aagaacccac tgattggacc acatcgaata ccgagatgtg cgaggtgggg      660

caggtgtgtc aggagacgct gctgctcata gatgtaggac tcacatcaac cctggtgggg      720

acaaaaggct gcagcactgt tggggctcaa aattcccaga agaccaccat ccactcagcc      780

cctcctgggg tgcttgtggc ctcctatacc cacttctgct cctcggacct gtgcaatagt      840

gccagcagca gcagcgttct gctgaactcc ctccctcctc aagctgcccc tgtcccagga      900

gaccggcagt gtcctacctg tgtgcagccc cttggaacct gttcaagtgg ctccccccga      960

atgacctgcc ccaggggcgc cactcattgt tatgatgggt acattcatct ctcaggaggt     1020

gggctgtcca ccaaaatgag cattcagggc tgcgtggccc aaccttccag cttcttgttg     1080

aaccacacca gacaaatcgg gatcttctct gcgcgtgaga agcgtgatgt gcagcctcct     1140

gcctctcagc atgagggagg t                                               1161


<210>  4199
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  4199
ctgctgtgct actcctgcaa agcccaggtg agcaacgagg actgcctgca ggtggagaac       60

tgcacccagc tgggggagca gtgctggacc gcgcgcatcc gcgcagttgg cctcctgacc      120

gtcatcagca aaggctgcag cttgaactgc gtggatgact cacaggacta ctacgtgggc      180

aagaagaaca tcacgtgctg tgacaccgac ttgtgcaacg ccagc                      225


<210>  4200
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  4200
caagtcacga ttgaagccga gccaaccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttaccggc tacatctggt acaaagggca aatgagggac      120

ctctaccatt acattacatc atatgtagta gacggtgaaa taattatata tgggcctgca      180

tatagtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagggag atgatgggac tagaggagta      300

actggacgtt tcaccttcac cttacacctg gagactccta agccctccat ctccagcagc      360

aacttaaatc ccagggagac catggaggct gtgagcttaa cctgtgaccc tgagactcca      420

gacgcaagct acctgtggtg gatgaatggt cagagcctcc ctatgactca cagcttgaag      480

ctgtccgaaa ccaacaggac cctctttcta ttgggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagccgca gtgacccagt caccctgaat      600

ctcctcccga agctgcccaa gccctacatc accatcaaca acttaaaccc cagggagaat      660

aaggatgtct taaacttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaatggtc agagcctccc ggtcagtccc agggtaaagc gacccattga aaacaggatc      780

ctcattctac ccagtgtcac gagaaatgaa acaggaccct atcaatgtga aatacgggac      840

cgatatggtg gcatccgcag tgacccagtc accctgaatg tcctctatgg tccagacctc      900

cccagaattt acccttcatt cacctattac cgttcaggag aagtcctcta cttgtcctgt      960

tctgcggact ctaacccacc ggcacagtat tcttggacaa ttaatgaaaa gtttcagcta     1020

ccaggacaaa agctctttat ccgccatatt actacaaagc atagcgggct ctatgtttgc     1080

tctgttcgta actcagccac tggcaaggaa agctccaaat ccatgacagt cgaagtctct     1140

gactggacag ttccc                                                      1155


<210>  4201
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  4201
caagtcacga ttgaagccga gccaaccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttaccggc tacatctggt acaaagggca aatgagggac      120

ctctaccatt acattacatc atatgtagta gacggtgaaa taattatata tgggcctgca      180

tatagtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagggag atgatgggac tagaggagta      300

actggacgtt tcaccttcac cttacacctg gagactccta agccctccat ctccagcagc      360

aacttaaatc ccagggagac catggaggct gtgagcttaa cctgtgaccc tgagactcca      420

gacgcaagct acctgtggtg gatgaatggt cagagcctcc ctatgactca cagcttgaag      480

ctgtccgaaa ccaacaggac cctctttcta ttgggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagccgca gtgacccagt caccctgaat      600

ctcctcccga agctgcccaa gccctacatc accatcaaca acttaaaccc cagggagaat      660

aaggatgtct taaacttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaatggtc agagcctccc ggtcagtccc agggtaaagc gacccattga aaacaggatc      780

ctcattctac ccagtgtcac gagaaatgaa acaggaccct atcaatgtga aatacgggac      840

cgatatggtg gcatccgcag tgacccagtc accctgaatg tcctctatgg tccagacctc      900

cccagaattt acccttcatt cacctattac cgttcaggag aagtcctcta cttgtcctgt      960

tctgcggact ctaacccacc ggcacagtat tcttggacaa ttaatgaaaa gtttcagcta     1020

ccaggacaaa agctctttat ccgccatatt actacaaagc atagcgggct ctatgtttgc     1080

tctgttcgta actcagccac tggcaaggaa agctccaaat ccatgacagt cgaagtctct     1140

ggtaagtgga tcccagcatc gttggcaata gggttt                               1176


<210>  4202
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  4202
caagtcacga ttgaagccca gccaccaaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttactggc tacatctggt acaaagggca aatcagggac      120

ctctaccatt acattacatc atatgtagta gacggtcaaa taattatata tgggcctgca      180

tatagtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagcgag gtgatgggac tagaggagta      300

actggatatt tcaccttcac cttatacctg gagactccca agccctccat ctccagcagc      360

aacttaaacc ccagggaggc catggaaact gtgatcttaa cctgtgatcc tgagactccg      420

gacacaagct accagtggtg gatgaatggt cagagcctcc ctatgactca caggtttcag      480

ctgtccgaaa ccaacaggac cctctttcta tttggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa ctcagggagt gccagccgca gtgacccagt caccctgaat      600

ctcctccatg gtccagacct ccccagaatt cacccttcat acaccaatta ccgttcagga      660

gataacctct acttgtcttg cttcgcgaac tctaacccac cggcacagta ttcttggaca      720

attaatggga agtttcagca atcaggacaa aatctgttta tcccccaaat tactacaaag      780

catagcgggc tctatgtttg ctctgttcgt aactcagcca ctggcgagga aagctccacg      840

tcgttgacag tcaaagtctc tgcttctaca agaataggac ttcttcctct ccttaatcca      900

acatggatcc acccagcttt cttgtac                                          927


<210>  4203
<211>  903
<212>  DNA
<213>  Homo Sapiens

<400>  4203
caagtcacga ttgaagccca gccaccaaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttactggc tacatctggt acaaagggca aatcagggac      120

ctctaccatt acattacatc atatgtagta gacggtcaaa taattatata tgggcctgca      180

tatagtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagcgag gtgatgggac tagaggagta      300

actggatatt tcaccttcac cttatacctg gagactccca agccctccat ctccagcagc      360

aacttaaacc ccagggaggc catggaaact gtgatcttaa cctgtgatcc tgagactccg      420

gacacaagct accagtggtg gatgaatggt cagagcctcc ctatgactca caggtttcag      480

ctgtccgaaa ccaacaggac cctctttcta tttggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa ctcagggagt gccagccgca gtgacccagt caccctgaat      600

ctcctccatg gtccagacct ccccagaatt cacccttcat acaccaatta ccgttcagga      660

gataacctct acttgtcttg cttcgcgaac tctaacccac cggcacagta ttcttggaca      720

attaatggga agtttcagca atcaggacaa aatctgttta tcccccaaat tactacaaag      780

catagcgggc tctatgtttg ctctgttcgt aactcagcca ctggcgagga aagctccacg      840

tcgttgacag tcaaagtctc tgcttctaca agaataggac ttcttcctct ccttaatcca      900

aca                                                                    903


<210>  4204
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  4204
caagtcacga ttgaagccga gccaaccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttaccggc tacatctggt acaaagggca aatgagggac      120

ctctaccatt acattacatc atatgtagta gacggtgaaa taattatata tgggcctgca      180

tatggtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagggag atgatgggac tagaggagta      300

actggacgtt tcaccttcac cttacacctg gagactccta agccctccat ctccagcagc      360

aacttaaatc ccagggagac catggaggct gtgagcttaa cctgtgaccc tgagactcca      420

gacgcaagct acctgtggtg gatgaatggt cagagcctcc ctatgactca cagcttgaag      480

ctgtccgaaa ccaacaggac cctctttcta ttgggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagccgca gtgacccagt caccctgaat      600

ctcctcccaa agctgtccaa gccctacatc acaatcaaca acttaaaccc cagagagaat      660

aaggatgtct taaccttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaatggtc agagcctccc tgtcagtccc agggtaaagc gacccattga aaacaggatc      780

ctcattctac ccaatgtcac gagaaatgaa acaggacctt atcaatgtga aatacgggac      840

cgatatggtg gcatccgcag tgacccagtc accctgaatg tcctctatgg tccagacctc      900

cccagcattt acccttcatt cacctattac cgttcaggag aaaacctcta cttgtcctgc      960

ttcgccgagt ctaacccacg ggcacaatat tcttggacaa ttaatgggaa gtttcagcta     1020

tcaggacaaa agctctctat cccccaaata actacaaagc atagtgggct ctatgcttgc     1080

tctgttcgta actcagccac tggcaaggaa agctccaaat ccatcacagt caaagtctct     1140

gactggatat taccc                                                      1155


<210>  4205
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  4205
caagtcacga ttgaagccga gccaaccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttaccggc tacatctggt acaaagggca aatgagggac      120

ctctaccatt acattacatc atatgtagta gacggtgaaa taattatata tgggcctgca      180

tatggtggac gagaaacagc atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaggacgcag gatcctacac cttacacatc ataaagggag atgatgggac tagaggagta      300

actggacgtt tcaccttcac cttacacctg gagactccta agccctccat ctccagcagc      360

aacttaaatc ccagggagac catggaggct gtgagcttaa cctgtgaccc tgagactcca      420

gacgcaagct acctgtggtg gatgaatggt cagagcctcc ctatgactca cagcttgaag      480

ctgtccgaaa ccaacaggac cctctttcta ttgggtgtca caaagtatac tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagccgca gtgacccagt caccctgaat      600

ctcctcccaa agctgtccaa gccctacatc acaatcaaca acttaaaccc cagagagaat      660

aaggatgtct taaccttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaatggtc agagcctccc tgtcagtccc agggtaaagc gacccattga aaacaggatc      780

ctcattctac ccaatgtcac gagaaatgaa acaggacctt atcaatgtga aatacgggac      840

cgatatggtg gcatccgcag tgacccagtc accctgaatg tcctctatgg tccagacctc      900

cccagcattt acccttcatt cacctattac cgttcaggag aaaacctcta cttgtcctgc      960

ttcgccgagt ctaacccacg ggcacaatat tcttggacaa ttaatgggaa gtttcagcta     1020

tcaggacaaa agctctctat cccccaaata actacaaagc atagtgggct ctatgcttgc     1080

tctgttcgta actcagccac tggcaaggaa agctccaaat ccatcacagt caaagtctct     1140

gactggatat taccc                                                      1155


<210>  4206
<211>  903
<212>  DNA
<213>  Homo Sapiens

<400>  4206
caagtcacga ttgaagccct gccacccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgcctcagaa tcttgctggc tacatctggt acaaaggaca actgatggac      120

ctctaccatt acattacatc atatgtagta gacggtcaaa taaatatata tgggcctgca      180

tacactggac gagaaacagt atattccaat gcatccctgc tgatccagaa tgtcacccgg      240

gaagacgcag gatcctatac cttacacatc ataaagcgag gtgataggac tagaggagta      300

actggatatt tcaccttcaa cttatacctg aagctgccca agccctacat caccatcaac      360

aactcaaaac ccagggagaa taaggatgtc ttagccttca cctgtgaacc taagagtgag      420

aactacacct acatttggtg gctaaatggt cagagcctcc cggtcagtcc cagggtaaag      480

caacccattg aaaacaggat cctcattcta cccagtgtca cgagaaatga aacaggaccc      540

tatgaatgtg aaatacggga ccgagatggt ggcatgcaca gtgacccagt caccctgaat      600

gtcctctatg gtccagacct ccccagcatt tacccttcat tcacctatta ccgttcagga      660

gaaaacctct acttgtcctg cttcgcggaa tctaacccac cggcagagta tttttggaca      720

attaatggga agtttcagca atcaggacaa aagctctcta tcccccaaat tactacaaag      780

catagagggc tctatacttg ctctgttcgt aactcagcca ctggcaagga aagctccaaa      840

tccatgacag tcgaagtctc tgctccttca ggaataggac gtcttcctct ccttaatcca      900

ata                                                                    903


<210>  4207
<211>  1170
<212>  DNA
<213>  Homo Sapiens

<400>  4207
caagtaataa ttgaagccaa gccacccaaa gtttccgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttactggc tacatctggt acaaagggca aatgacggac      120

ctctaccatt acattacatc atatgtagta cacggtcaaa ttatatatgg gcctgcctac      180

agtggacgag aaacagtata ttccaatgca tccctgctga tccagaatgt cacacaggag      240

gatgcaggat cctacacctt acacatcata aagcgaggcg atgggactgg aggagtaact      300

ggatatttca ctgtcacctt atactcggag actcccaagc cctccatctc cagcagcaac      360

ttaaacccca gggaggtcat ggaggctgtg cgcttaatct gtgatcctga gactccggat      420

gcaagctacc tgtggttgct gaatggtcag aacctcccta tgactcacag gttgcagctg      480

tccaaaacca acaggaccct ctatctattt ggtgtcacaa agtatattgc aggaccctat      540

gaatgtgaaa tacggaaccc agtgagtgcc agccgcagtg acccagtcac cctgaatctc      600

ctcccgaagc tgcccatgcc ttacatcacc atcaacaact taaaccccag ggagaagaag      660

gatgtgttag ccttcacctg tgaacctaag agtcggaact acacctacat ttggtggcta      720

aatggtcaga gcctcccggt cagtccgagg gtaaagcgac ccattgaaaa caggatactc      780

attctaccca gtgtcacgag aaatgaaaca ggaccctatc aatgtgaaat acgggaccga      840

tatggtggca tccgcagtaa cccagtcacc ctgaatgtcc tctatggtcc agacctcccc      900

agaatttacc cttcattcac ctattaccgt tcaggagaaa acctcgactt gtcctgcttt      960

gcggactcta acccaccggc agagtattct tggacaatta atgggaagtt tcagctatca     1020

ggacaaaagc tctttatccc ccaaattact acaaatcata gcgggctcta tgcttgctct     1080

gttcgtaact cagccactgg caaggaaatc tccaaatcca tgatagtcaa agtctctggt     1140

ccctgccatg gaaaccagac agagtctcat                                      1170


<210>  4208
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  4208
caagtcacga ttgaagccca gccaaccaaa gtttctgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttactggc tacatctggt acaaagggca aatcagggac      120

ctctaccatt acattacatc atatgtagta gacggtcaaa taattatata tgggcctgca      180

tacagtggac gagaaacaat atattccaat gcatccctgc tgatccagaa tgtcacccag      240

gaagacgcag gatcctacac cttacacatc ataatgggag gtgatgagaa tagaggagta      300

actggacatt tcaccttcac cttatatctg gagactccca agccctccat ctccagcagc      360

aaattaaacc ccagggaggc catggaggct gtgagcttaa cctgtgatcc tgagactccg      420

gacgcaagct acctgtggtg gatgaatggt cagagcctcc ctatgtctca caggttgcag      480

ttgtctgaaa ccaacaggac cctctttcta ttgggtgtca caaagtacac tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagccgca gtgacccatt caccctgaat      600

ctcctcccga agctgcccaa gccctacatc accatcaaca acttaaaacc cagggagaat      660

aaggatgtct taaacttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaatggtc agagcctccc ggtcagtccc agggtaaagc gacccattga aaacaggatc      780

ctcattctac ccagtgtcac gagaaatgaa acaggaccct atcaatgtga aataagggac      840

caatatggtg gcatccgcag ttacccagtc accctgaatg tcctctatgg tccagacctc      900

cccagaattt acccttcatt cacctattac cgttcaggag aagtcctcta cttgtcctgt      960

tctgcggact ctaacccacc ggcacagtat tcttggacaa ttaatgggaa gtttcagcta     1020

tcaggacaaa agctctttat cccccaaatt actacaaagc atagcgggct ctatgcttgc     1080

tctgttcgta actcagccac tggcaaggaa agctccaaat ccatgacagt aaaagtctct     1140

ggtaagcgga tcccagtatc cttggcaata gggatt                               1176


<210>  4209
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  4209
gaagtcacga ttgaagccca gccacccaaa gtttctgagg ggaaggatgt tcttctactt       60

gtccacaatt tgccccagaa tcttcctggc tacttctggt acaaagggga aatgacggac      120

ctctaccatt acattatatc gtatatagtt gatggtaaaa taattatata tgggcctgca      180

tacagtggaa gagaaacagt atattccaac gcatccctgc tgatccagaa tgtcacccgg      240

aaggatgcag gaacctacac cttacacatc ataaagcgag gtgatgagac tagagaagaa      300

attcgacatt tcaccttcac cttatacttg gagactccca agccctacat ctccagcagc      360

aacttaaacc ccagggaggc catggaggct gtgcgcttaa tctgtgatcc tgagactctg      420

gacgcaagct acctatggtg gatgaatggt cagagcctcc ctgtgactca caggttgcag      480

ctgtccaaaa ccaacaggac cctctatcta tttggtgtca caaagtatat tgcaggaccc      540

tatgaatgtg aaatacggaa cccagtgagt gccagtcgca gtgacccagt caccctgaat      600

ctcctcccga agctgcccat cccctacatc accatcaaca acttaaaccc cagggagaat      660

aaggatgtct tagccttcac ctgtgaacct aagagtgaga actacaccta catttggtgg      720

ctaaacggtc agagcctccc cgtcagtccc ggggtaaagc gacccattga aaacaggata      780

ctcattctac ccagtgtcac gagaaatgaa acaggaccct atcaatgtga aatacaggac      840

cgatatggtg gcctccgcag taacccagtc atcctaaatg tcctctatgg tccagacctc      900

cccagaattt acccttcatt cacctattac cgttcaggag aaaacctcga cttgtcctgc      960

ttcacggaat ctaacccacc ggcagagtat ttttggacaa ttaatgggaa gtttcagcaa     1020

tcaggacaaa agctctttat cccccaaatt actagaaatc atagcgggct ctatgcttgc     1080

tctgttcata actcagccac tggcaaggaa atctccaaat ccatgacagt caaagtctct     1140

ggtccctgcc atggagacct gacagagtct cagtca                               1176


<210>  4210
<211>  405
<212>  DNA
<213>  Homo Sapiens

<400>  4210
tggggccccg atgcccgtgg ggttcccgtg gccgatggag agttctcgtc tgaacaggtg       60

gcaaaggctg gagggacctg gctgggcacc caccgccccc ttgcccgcct gcgccgagcc      120

ctgtctggtc catgccagct gtggagcctg accctgtccg tggcagagct aggcctgggc      180

tacgcctcag aggagaaggt catcttccgc tactgcgccg gcagctgccc ccgtggtgcc      240

cgcacccagc atggcctggc gctggcccgg ctgcagggcc agggccgagc ccacggcggg      300

ccctgctgcc ggcccactcg ctacaccgac gtggccttcc tcgatgaccg ccaccgctgg      360

cagcggctgc cccagctctc ggcggctgcc tgcggctgtg gtggc                      405


<210>  4211
<211>  1728
<212>  DNA
<213>  Homo Sapiens

<400>  4211
gcggacccag gggcgcccac gccagtgaat ccctgttgtt actatccatg ccagcaccag       60

ggcatctgtg tccgcttcgg ccttgaccgc taccagtgtg actgcacccg cacgggctat      120

tccggcccca actgcaccat ccctggcctg tggacctggc tccggaattc actgcggccc      180

agcccctctt tcacccactt cctgctcact cacgggcgct ggttctggga gtttgtcaat      240

gccaccttca tccgagagat gctcatgcgc ctggtactca cagtgcgctc caaccttatc      300

cccagtcccc ccacctacaa ctcagcacat gactacatca gctgggagtc tttctccaac      360

gtgagctatt acactcgtat tctgccctct gtgcctaaag attgccccac acccatggga      420

accaaaggga agaagcagtt gccagatgcc cagctcctgg cccgccgctt cctgctcagg      480

aggaagttca tacctgaccc ccaaggcacc aacctcatgt ttgccttctt tgcacaacac      540

ttcacccacc agttcttcaa aacttctggc aagatgggtc ctggcttcac caaggccttg      600

ggccatgggg tagacctcgg ccacatttat ggagacaatc tggagcgtca gtatcaactg      660

cggctcttta aggatgggaa actcaagtac caggtgctgg atggagaaat gtacccgccc      720

tcggtagaag aggcgcctgt gttgatgcac tacccccgag gcatcccgcc ccagagccag      780

atggctgtgg gccaggaggt gtttgggctg cttcctgggc tcatgctgta tgccacgctc      840

tggctacgtg agcacaaccg tgtgtgtgac ctgctgaagg ctgagcaccc cacctggggc      900

gatgagcagc ttttccagac gacccgcctc atcctcatag gggagaccat caagattgtc      960

atcgaggagt acgtgcagca gctgagtggc tatttcctgc agctgaaatt tgacccagag     1020

ctgctgttcg gtgtccagtt ccaataccgc aaccgcattg ccatggagtt caaccatctc     1080

taccactggc accccctcat gcctgactcc ttcaaggtgg gctcccagga gtacagctac     1140

gagcagttct tgttcaacac ctccatgttg gtggactatg gggttgaggc cctggtggat     1200

gccttctctc gccagattgc tggccggatc ggtgggggca ggaacatgga ccaccacatc     1260

ctgcatgtgg ctgtggatgt catcagggag tctcgggaga tgcggctgca gcccttcaat     1320

gagtaccgca agaggtttgg catgaaaccc tacacctcct tccaggagct cgtaggagag     1380

aaggagatgg cagcagagtt ggaggaattg tatggagaca ttgatgcgtt ggagttctac     1440

cctggactgc ttcttgaaaa gtgccatcca aactctatct ttggggagag tatgatagag     1500

attggggctc ccttttccct caagggtctc ctagggaatc ccatctgttc tccggagtac     1560

tggaagccga gcacatttgg cggcgaggtg ggctttaaca ttgtcaagac ggccacactg     1620

aagaagctgg tctgcctcaa caccaagacc tgtccctacg tttccttccg tgtgccggat     1680

gccagtcagg atgatgggcc tgctgtggag cgaccatcca cagagctc                  1728


<210>  4212
<211>  1761
<212>  DNA
<213>  Homo Sapiens

<400>  4212
gcaaatcctt gctgttccca cccatgtcaa aaccgaggtg tatgtatgag tgtgggattt       60

gaccagtata agtgcgattg tacccggaca ggattctatg gagaaaactg ctcaacaccg      120

gaatttttga caagaataaa attatttctg aaacccactc caaacacagt gcactacata      180

cttacccact tcaagggatt ttggaacgtt gtgaataaca ttcccttcct tcgaaatgca      240

attatgagtt atgtgttgac atccagatca catttgattg acagtccacc aacttacaat      300

gctgactatg gctacaaaag ctgggaagcc ttctctaacc tctcctatta tactagagcc      360

cttcctcctg tgcctgatga ttgcccgact cccttgggtg tcaaaggtaa aaagcagctt      420

cctgattcaa atgagattgt ggaaaaattg cttctaagaa gaaagttcat ccctgatccc      480

cagggctcaa acatgatgtt tgcattcttt gcccagcact tcacgcatca gtttttcaag      540

acagatcata agcgagggcc agctttcacc aacgggctgg gccatggggt ggacttaaat      600

catatttacg gtgaaactct ggctagacag cgtaaactgc gccttttcaa ggatggaaaa      660

atgaaatatc agataattga tggagagatg tatcctccca cagtcaaaga tactcaggca      720

gagatgatct accctcctca agtccctgag catctacggt ttgctgtggg gcaggaggtc      780

tttggtctgg tgcctggtct gatgatgtat gccacaatct ggctgcggga acacaacaga      840

gtatgcgatg tgcttaaaca ggagcatcct gaatggggtg atgagcagtt gttccagaca      900

agcaggctaa tactgatagg agagactatt aagattgtga ttgaagatta tgtgcaacac      960

ttgagtggct atcacttcaa actgaaattt gacccagaac tacttttcaa caaacaattc     1020

cagtaccaaa atcgtattgc tgctgaattt aacaccctct atcactggca tccccttctg     1080

cctgacacct ttcaaattca tgaccagaaa tacaactatc aacagtttat ctacaacaac     1140

tctatattgc tggaacatgg aattacccag tttgttgaat cattcaccag gcaaattgct     1200

ggcagggttg ctggtggtag gaatgttcca cccgcagtac agaaagtatc acaggcttcc     1260

attgaccaga gcaggcagat gaaataccag tcttttaatg agtaccgcaa acgctttatg     1320

ctgaagccct atgaatcatt tgaagaactt acaggagaaa aggaaatgtc tgcagagttg     1380

gaagcactct atggtgacat cgatgctgtg gagctgtatc ctgcccttct ggtagaaaag     1440

cctcggccag atgccatctt tggtgaaacc atggtagaag ttggagcacc attctccttg     1500

aaaggactta tgggtaatgt tatatgttct cctgcctact ggaagccaag cacttttggt     1560

ggagaagtgg gttttcaaat catcaacact gcctcaattc agtctctcat ctgcaataac     1620

gtgaagggct gtccctttac ttcattcagt gttccagatc cagagctcat taaaacagtc     1680

accatcaatg caagttcttc ccgctccgga ctagatgata tcaatcccac agtactacta     1740

aaagaacgtt cgactgaact g                                               1761


<210>  4213
<211>  2022
<212>  DNA
<213>  Homo Sapiens

<400>  4213
gccattgtct tcatcaagca gccgtcctcc caggatgcac tgcaggggcg ccgggcgctg       60

cttcgctgtg aggttgaggc tccgggcccg gtacatgtgt actggctgct cgatggggcc      120

cctgtccagg acacggagcg gcgtttcgcc cagggcagca gcctgagctt tgcagctgtg      180

gaccggctgc aggactctgg caccttccag tgtgtggctc gggatgatgt cactggagaa      240

gaagcccgca gtgccaacgc ctccttcaac atcaaatgga ttgaggcagg tcctgtggtc      300

ctgaagcatc cagcctcgga agctgagatc cagccacaga cccaggtcac acttcgttgc      360

cacattgatg ggcaccctcg gcccacctac caatggttcc gagatgggac ccccctttct      420

gatggtcaga gcaaccacac agtcagcagc aaggagcgga acctgacgct ccggccagct      480

ggtcctgagc atagtgggct gtattcctgc tgcgcccaca gtgcttttgg ccaggcttgc      540

agcagccaga acttcacctt gagcattgct gatgaaagct ttgccagggt ggtgctggca      600

ccccaggacg tggtagtagc gaggtatgag gaggccatgt tccattgcca gttctcagcc      660

cagccacccc cgagcctgca gtggctcttt gaggatgaga ctcccatcac taaccgcagt      720

cgccccccac acctccgcag agccacagtg tttgccaacg ggtctctgct gctgacccag      780

gtccggccac gcaatgcagg gatctaccgc tgcattggcc aggggcagag gggcccaccc      840

atcatcctgg aagccacact tcacctagca gagattgaag acatgccgct atttgagcca      900

cgggtgttta cagctggcag cgaggagcgt gtgacctgcc ttccccccaa gggtctgcca      960

gagcccagcg tgtggtggga gcacgcggga gtccggctgc ccacccatgg cagggtctac     1020

cagaagggcc acgagctggt gttggccaat attgctgaaa gtgatgctgg tgtctacacc     1080

tgccacgcgg ccaacctggc tggtcagcgg agacaggatg tcaacatcac tgtggccact     1140

gtgccctcct ggctgaagaa gccccaagac agccagctgg aggagggcaa acccggctac     1200

ttggattgcc tgacccaggc cacaccaaaa cctacagttg tctggtacag aaaccagatg     1260

ctcatctcag aggactcacg gttcgaggtc ttcaagaatg ggaccttgcg catcaacagc     1320

gtggaggtgt atgatgggac atggtaccgt tgtatgagca gcaccccagc cggcagcatc     1380

gaggcgcaag cccgtgtcca agtgctggaa aagctcaagt tcacaccacc accccagcca     1440

cagcagtgca tggagtttga caaggaggcc acggtgccct gttcagccac aggccgagag     1500

aagcccacta ttaagtggga acgggcagat gggagcagcc tcccagagtg ggtgacagac     1560

aacgctggga ccctgcattt tgcccgggtg actcgagatg acgctggcaa ctacacttgc     1620

attgcctcca acgggccgca gggccagatt cgtgcccatg tccagctcac tgtggcagtt     1680

tttatcacct tcaaagtgga accagagcgt acgactgtgt accagggcca cacagcccta     1740

ctgcagtgcg aggcccaggg ggaccccaag ccgctgattc agtggaaagg caaggaccgc     1800

atcctggacc ccaccaagct gggacccagg atgcacatct tccagaatgg ctccctggtg     1860

atccatgacg tggcccctga ggactcaggc cgctacacct gcattgcagg caacagctgc     1920

aacatcaagc acacggaggc ccccctctat gtcgtggaca agcctgtgcc ggaggagtcg     1980

gagggccctg gcagccctcc cccctacaag atgatccaga cc                        2022


<210>  4214
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  4214
ttccatgtgc aacaaacgga gatgtcacag actgtatcaa ctggggagtc aatcatcttg       60

agttgcagcg tacccgatac cttaccaaat ggacctgtct tgtggttcaa gggaacaggg      120

ccaaaccgga aattaatcta caatttcaaa caaggtaact ttcccagagt aaaagagatt      180

ggagacacca ccaagcctgg caacacagac ttttccaccc gcatccgtga aatctctctt      240

gctgatgctg gcacctatta ctgcgtgaag ttcataaaag gaagagctat caaggagtac      300

caatcaggtc ggggcactca ggtgtttgtt actgagcaga atccaagacc tcccaagaac      360

agacctgcag gcagagcagg ctccagggcc caccatgatg cccatacctg cctctcggcc      420

ctgcctgaga gaaacagcac aaactatttc gtccaaccct gctgctgcct ccggctgctg      480

ggactcacag gcttgctgtc aaaa                                             504


<210>  4215
<211>  4797
<212>  DNA
<213>  Homo Sapiens

<400>  4215
gagccagaga gatgtaactt caccctggcg gagtccaagg cctccagcca ttctgtgtct       60

atccagtgga gaattttggg ctcaccctgt aactttagcc tcatctatag cagtgacacc      120

ctgggggccg cgttgtgccc tacctttcgg atagacaaca ccacatacgg atgtaacctt      180

caagatttac aagcaggaac catctataac ttcaggatta tttctctgga tgaagagaga      240

acagtggtct tgcaaacaga tcctttacct cctgctaggt ttggagtcag taaagagaag      300

acgacttcaa ccagcttgca tgtttggtgg actccttctt ccggaaaagt cacctcatat      360

gaggtgcaat tatttgatga aaataaccaa aagatacagg gggttcaaat tcaagaaagt      420

acttcatgga atgaatacac ttttttcaat ctcactgctg gtagtaaata caatattgcc      480

atcacagctg tttctggagg aaaacgttct ttttcagttt ataccaatgg atcaacagtg      540

ccatctccag tgaaagatat tggtatttcc acaaaagcca attctctcct gatttcctgg      600

tcccatggtt ctgggaatgt ggaacgatac cggctgatgc taatggataa agggatccta      660

gttcatggcg gtgttgtgga caaacatgct acttcctatg cttttcacgg gctgacccct      720

ggctacctct acaacctcac tgttatgact gaggctgcag ggctgcaaaa ctacaggtgg      780

aaactagtca ggacagcccc catggaagtc tcaaatctga aggtgacaaa tgatggcagt      840

ttgacctctc taaaagtcaa atggcaaaga cctcctggaa atgtggattc ttacaatatc      900

accctgtctc acaaagggac catcaaggaa tccagagtat tagcaccttg gattactgaa      960

actcacttta aagagttagt ccccggtcga ctttatcaag ttactgtcag ctgtgtctct     1020

ggtgaactgt ctgctcagaa gatggcagtg ggcagaacat ttccagacaa agttgcaaac     1080

ctggaggcaa acaataatgg caggatgagg tctcttgtag tgagctggtc gccccctgct     1140

ggagactggg agcagtatcg gatcctactc ttcaatgatt ctgtggtgct gctcaacatc     1200

actgtgggaa aggaagaaac acagtatgtc atggatgaca cggggctcgt accgggaaga     1260

cagtatgagg tggaagtcat tgttgagagt ggaaatttga agaattctga gcgttgccaa     1320

ggcaggacag tccccctggc tgtcctccag cttcgtgtca aacatgccaa tgaaacctca     1380

ctgagtatca tgtggcagac ccctgtagca gaatgggaga aatacatcat ttccctagct     1440

gacagagacc tcttactgat ccacaagtca ctctccaaag atgccaaaga attcactttt     1500

actgacctgg tgcctggacg aaaatacatg gctacagtca ccagtattag tggagactta     1560

aaaaattcct cttcagtaaa aggaagaaca gtgcctgccc aagtgactga cttgcatgtg     1620

gccaaccaag gaatgaccag tagtctgttt actaactgga cccaggcaca aggagacgta     1680

gaattttacc aagtcttact gatccatgaa aatgtggtca ttaaaaatga aagcatctcc     1740

agtgagacca gcagatacag cttccactct ctcaagtccg gcagcctgta ctccgtggtg     1800

gtaacaacag tgagtggagg gatctcttcc cgacaagtgg ttgtggaggg aagaacagtc     1860

ccttccagtg tgagtggagt aacggtgaac aattccggtc gtaatgacta cctcagcgtt     1920

tcctggctgc tggcgcccgg agatgtggat aactatgagg taacattgtc tcatgacggc     1980

aaggtggttc agtcccttgt cattgccaag tctgtcagag aatgttcctt cagctccctc     2040

accccaggcc gcctctacac cgtgaccata actacaagga gtggcaagta tgaaaatcac     2100

tccttcagcc aagagcggac agtgcctgac aaagtccagg gagtcagtgt tagcaactca     2160

gccaggagtg actatttaag ggtatcctgg gtgcatgcca ctggagactt tgatcactat     2220

gaagtcacca ttaaaaacaa aaacaacttc attcaaacta aaagcattcc caagtcagaa     2280

aacgaatgtg tatttgttca gctagtccct ggacggttgt acagtgtcac tgttactaca     2340

aaaagtggac aatatgaagc caatgaacaa gggaatggga gaacaattcc agagcctgtt     2400

aaggatctaa cattgcgcaa caggagcact gaggacttgc atgtgacttg gtcaggagct     2460

aatggggatg tcgaccaata tgagatccag ctgctcttca atgacatgaa agtatttcct     2520

ccttttcacc ttgtaaatac cgcaaccgag tatcgattta cttccctaac accaggccgc     2580

caatacaaaa ttcttgtctt gacgattagc ggggatgtac agcagtcagc cttcattgag     2640

ggcttcacag ttcctagtgc tgtcaaaaat attcacattt ctcccaatgg agcaacagat     2700

agcctgacgg tgaactggac tcctggtggg ggagacgttg attcctacac ggtgtcggca     2760

ttcaggcaca gtcaaaaggt tgactctcag actattccca agcacgtctt tgagcacacg     2820

ttccacagac tggaggccgg ggagcagtac cagatcatga ttgcctcagt cagcgggtcc     2880

ctgaagaatc agataaatgt ggttgggcgg acagttccag catctgtcca aggagtaatt     2940

gcagacaatg catacagcag ttattcctta atagtaagtt ggcaaaaagc tgctggtgtg     3000

gcagaaagat atgatatcct gcttctaact gaaaatggaa tccttctgcg caacacatca     3060

gagccagcca ccactaagca acacaaattt gaagatctaa caccaggcaa gaaatacaag     3120

atacagatcc taactgtcag tggaggcctc tttagcaagg aagcccagac tgaaggccga     3180

acagtcccag cagctgtcac cgacctgagg atcacagaga actccaccag gcacctgtcc     3240

ttccgctgga ccgcctcaga gggggagctc agctggtaca acatcttttt gtacaaccca     3300

gatgggaatc tccaggagag agctcaagtt gacccactag tccagagctt ctctttccag     3360

aacttgctac aaggcagaat gtacaagatg gtgattgtaa ctcacagtgg ggagctgtct     3420

aatgagtctt tcatatttgg tagaacagtc ccagcctctg tgagtcatct cagggggtcc     3480

aatcggaaca cgacagacag cctttggttc aactggagtc cagcctctgg ggactttgac     3540

ttttatgagc tgattctcta taatcccaat ggcacaaaga aggaaaactg gaaagacaag     3600

gacctgacgg agtggcggtt tcaaggcctt gttcctggaa ggaagtacgt gctgtgggtg     3660

gtaactcaca gtggagatct cagcaataaa gtcacagcgg agagcagaac agctccaagt     3720

cctcccagtc ttatgtcatt tgctgacatt gcaaacacat ccttggccat cacgtggaaa     3780

gggcccccag actggacaga ctacaacgac tttgagctgc agtggttgcc cagagatgca     3840

cttactgtct tcaaccccta caacaacaga aaatcagaag gacgcattgt gtatggtctt     3900

cgtccaggga gatcctatca attcaacgtc aagactgtca gtggtgattc ctggaaaact     3960

tacagcaaac caatttttgg atctgtgagg acaaagcctg acaagataca aaacctgcat     4020

tgccggcctc agaactccac ggccattgcc tgttcttgga tccctcctga ttctgacttt     4080

gatggttata gtattgaatg ccggaaaatg gacacccaag aagttgagtt ttccagaaag     4140

ctggagaaag aaaaatctct gctcaacatc atgatgctag tgccccataa gaggtacctg     4200

gtgtccatca aagtgcagtc ggccggcatg accagcgagg tggttgaaga cagcactatc     4260

acaatgatag accgcccccc tcctccaccc ccacacattc gtgtgaatga aaaggatgtg     4320

ctaattagca agtcttccat caactttact gtcaactgca gctggttcag cgacaccaat     4380

ggagctgtga aatacttcac agtggtggtg agagaggctg atggcagtga tgagctgaag     4440

ccagaacagc agcaccctct cccttcctac ctggagtaca ggcacaatgc ctccattcgg     4500

gtgtatcaga ctaattattt tgccagcaaa tgtgccgaaa atcctaacag caactccaag     4560

agttttaaca ttaagcttgg agcagagatg gagagcctag gtggaaaatg cgatcccact     4620

cagcaaaaat tctgtgatgg accactgaag ccacacactg cctacagaat cagcattcga     4680

gcttttacac agctctttga tgaggacctg aaggaattca caaagccact ctattcagac     4740

acattttttt ctttacccat cactactgaa tcagagccct tgtttggagc tattgaa        4797


<210>  4216
<211>  1656
<212>  DNA
<213>  Homo Sapiens

<400>  4216
cagtcaccga cacctagccc cacaggacta actacagcaa agatgccctc tgtaccccta       60

tcaagtgacc ccttgcctac acacacaacc gctttttctc cggcctcaac ttttgaaaga      120

gagaacgatt ttagcgaaac cacaacatcc ctttcaccgg acaatacttc cactcaagtg      180

tcccccgaca gtctagataa tgcctctgcc tttaacacaa ccggcgtatc cagcgtgcag      240

accccgcacc tgccgaccca tgccgactcc cagactccgt cagcaggtac cgatacacag      300

acgttttctg gctcagcggc gaatgcgaaa cttaacccaa cccctggctc taatgcgatc      360

agcgacgtgc cgggggaacg ttctacagcc agcacttttc caactgaccc ggtgtcccca      420

cttacgacca cactttcatt ggcacaccac agcagtgccg ccctgcctgc aaggacctca      480

aacaccacga ttaccgcaaa tacttccgac gcgtatctaa acgctagcga gacaacgacc      540

ttgagtccat ccggctctgc cgtgattagt actacaacta ttgctactac tcctagtaaa      600

ccaacgtgcg atgaaaagta tgcgaatatc acagtggatt atttgtataa taaagagaca      660

aagttattca ccgccaaatt gaatgtcaat gagaacgtag agtgcggtaa caatacatgc      720

acgaacaatg aagtccataa cttgactgag tgcaagaacg catccgtaag catttcccac      780

aactcttgta ctgctcccga taagaccttg atactagacg tacccccagg ggtagaaaaa      840

tttcaattgc acgactgtac gcaagttgag aaagccgata cgacaatctg tttaaaatgg      900

aaaaatatag aaacctttac ctgtgacaca cagaatatca catataggtt tcagtgtggg      960

aacatgatct tcgacaacaa ggaaattaag ctggagaacc ttgaaccaga gcacgagtac     1020

aagtgcgaca gcgaaattct gtataacaac cacaaattca caaacgcatc caagattatc     1080

aaaacagact tcggatctcc cggtgaacca cagattatct tctgtcgttc tgaggccgcg     1140

caccagggcg tcattacatg gaatccgccg cagcgtagtt ttcataattt taccctatgc     1200

tatatcaaag aaacggagaa agactgtctg aatcttgata aaaatctaat caaatacgac     1260

ctacaaaatt taaaaccata tacgaagtat gtgctatcac ttcatgcgta cattatagca     1320

aaagtgcaaa gaaacggtag tgctgcgatg tgtcacttca ccacaaagtc cgcgccaccg     1380

tcacaggtct ggaacatgac agtctctatg acgtccgata acagcatgca tgtcaagtgt     1440

agaccaccac gtgacagaaa cgggcctcac gaacgttacc acttggaagt agaagctggg     1500

aacacattgg tcagaaacga gtcacacaag aattgtgatt ttagggtgaa agacttgcag     1560

tattccactg attatacttt caaggcatat tttcataatg gggattaccc aggggagccg     1620

ttcatattgc accattctac aagctacaat tctaag                               1656


<210>  4217
<211>  2502
<212>  DNA
<213>  Homo Sapiens

<400>  4217
gagacacctc caaggtttac acgaacaccc gttgatcaga caggggtctc tggcggagtt       60

gcctctttca tctgccaagc tacgggagac ccaagaccta aaattgtctg gaacaaaaaa      120

ggaaagaaag tcagcaatca gagatttgag gtaatagagt ttgacgatgg gtctggatca      180

gttctcagaa tacaaccctt acggactccg agggatgagg ccatttatga atgtgtggcc      240

tcaaataatg tgggagaaat aagtgtatcc accagactca cagttttgcg ggaagatcaa      300

attcccaggg gcttccctac cattgacatg ggcccacagt tgaaggtggt tgagcgtact      360

cgcacggcca ccatgctttg tgcagccagt ggtaatccgg atccagaaat cacttggttt      420

aaagatttct tacctgtgga cacaagcaac aacaatggtc gtattaagca gttacgatca      480

gaatctattg gtggtacacc aataagagga gcccttcaga ttgagcagag tgaagagtct      540

gaccaaggaa aatatgagtg tgttgccacc aacagcgcgg gcactcgcta ttccgctcct      600

gccaatttat atgtcagaga gctgcgagaa gttcgccgtg tcccaccaag attctctatc      660

ccacccacta atcatgaaat catgccaggc ggaagcgtta atatcacctg tgtggccgtg      720

gggtcaccaa tgccttatgt aaagtggatg ttgggggcag aagatctgac acctgaagat      780

gatatgccaa taggaagaaa tgtgctagaa ctgaatgatg taagacagtc agcaaattac      840

acctgtgttg ctatgtcaac actgggtgtc attgaagcaa tagcacagat cactgtcaaa      900

gccttaccca aacctccagg aactcctgta gtgaccgaga gcacagctac aagcatcaca      960

ctgacgtggg actctgggaa ccctgagcct gtttcttatt acataattca gcataaacct     1020

aaaaactctg aggaacttta caaagaaatt gatggggtgg cgaccacacg ctacagtgtc     1080

gctggactaa gtccctactc ggattatgaa ttcagggttg ttgctgtcaa taacattggg     1140

cgggggcctc ccagcgaacc tgtgctaaca caaacctcag agcaagcacc atccagtgcc     1200

ccgagggatg tccaggcacg aatgttgagt tcgaccacca ttttggtaca gtggaaggaa     1260

cctgaagagc caaatggaca gatccaagga tatagagttt attatacaat ggatcccact     1320

caacatgtca acaactggat gaaacacaat gtagctgaca gccaaatcac tactattggc     1380

aacttagtgc cccagaaaac atattctgtc aaagtcctgg cttttacctc aattggagat     1440

ggtccccttt caagtgacat acaagtcatc actcagacag gagtaccagg gcagccacta     1500

aacttcaaag cagaacctga gtctgaaaca agtattttgc tctcttggac acctccacgt     1560

tcagatacca ttgccaacta tgaactggtc tacaaagatg gggagcatgg agaggagcaa     1620

cgaattacca ttgagccagg gacatcatat aggctgcaag gactgaaacc aaacagctta     1680

tactatttcc gtctggctgc acgctcccct caaggcctgg gtgcttctac tgcagaaata     1740

tcagctagaa ccatgcagtc aatgtttgca aaaaattttc atgtcaaagc agtaatgaag     1800

acttccgtgt tgctgtcttg ggagattcca gagaattata actccgccat gcctttcaaa     1860

attctttatg atgatgggaa aatggtagaa gaagtggatg gccgagccac acagaagtta     1920

attgtcaacc tgaagcctga gaaatcatat tcatttgtgc tgacaaatcg tggaaacagt     1980

gctggtgggc tgcagcacag ggtcacggca aagactgcac cagatgtatt acgtaccaag     2040

cctgccttca ttgggaagac caacttggat ggcatgatta ctgtgcaact gcctgaagta     2100

cctgcaaatg agaatataaa aggttactac ataataattg tgcctttgaa gaaatctcgc     2160

gggaaattta tcaagccatg ggagagtcca gatgaaatgg aattagatga gctgcttaag     2220

gagatatcta ggaagcgcag aagcatccgt tatgggagag aagttgaatt aaagccatat     2280

attgccgctc actttgatgt ccttcccact gagttcaccc tgggggatga caagcattat     2340

ggtggattta caaacaagca actccaaagt ggtcaagaat atgtcttctt tgtgttagca     2400

gtaatggaac atgcagagtc taagatgtat gcaaccagcc cttactccga ccccgtggtg     2460

tcaatggatc tggatccgca gccaatcacg gatgaagaag aa                        2502


<210>  4218
<211>  3675
<212>  DNA
<213>  Homo Sapiens

<400>  4218
gacagcaaac ctgtcttcat taaagtccct gaggaccaga ctgggctgtc aggaggggta       60

gcctccttcg tgtgccaagc tacaggagaa cccaagccgc gcatcacatg gatgaagaag      120

gggaagaaag tcagctccca gcgcttcgag gtcattgagt ttgatgatgg ggcagggtca      180

gtgcttcgga tccagccatt gcgggtgcag cgagatgaag ccatctatga gtgtacagct      240

actaacagcc tgggtgagat caacactagt gccaagctct cagtgctcga agaggaacag      300

ctgccccctg ggttcccttc catcgacatg gggcctcagc tgaaggtggt ggagaaggca      360

cgcacagcca ccatgctatg tgccgcaggc ggaaatccag accctgagat ttcttggttc      420

aaggacttcc ttcctgtaga ccctgccacg agcaacggcc gcatcaagca gctgcgttca      480

ggtgccttgc agatagagag cagtgaggaa tccgaccaag gcaagtacga gtgtgtggcg      540

accaactcgg caggcacacg ttactcagcc cctgcgaacc tgtatgtgcg agtgcgccgc      600

gtggctcctc gtttctccat ccctcccagc agccaggagg tgatgccagg cggcagcgtg      660

aacctgacat gcgtggcagt gggtgcaccc atgccctacg tgaagtggat gatgggggcc      720

gaggagctca ccaaggagga tgagatgcca gttggccgca acgtcctgga gctcagcaat      780

gtcgtacgct ctgccaacta cacctgtgtg gccatctcct cgctgggcat gatcgaggcc      840

acagcccagg tcacagtgaa agctcttcca aagcctccga ttgatcttgt ggtgacagag      900

acaactgcca ccagtgtcac cctcacctgg gactctggga actcggagcc tgtaacctac      960

tatggcatcc agtaccgcgc agcgggcacg gagggcccct ttcaggaggt ggatggtgtg     1020

gccaccaccc gctacagcat tggcggcctc agccctttct cggaatatgc cttccgcgtg     1080

ctggcggtga acagcatcgg gcgagggccg cccagcgagg cagtgcgggc acgcacggga     1140

gaacaggcgc cctccagccc accgcgccgc gtgcaggcac gcatgctgag cgccagcacc     1200

atgctggtgc agtgggagcc tcccgaggag cccaacggcc tggtgcgggg ataccgcgtc     1260

tactatactc cggactcccg ccgccccccg aacgcctggc acaagcacaa caccgacgcg     1320

gggctcctca cgaccgtggg cagcctgctg cctggcatca cctacagcct gcgcgtgctt     1380

gccttcaccg ccgtgggcga tggccctccc agccccacca tccaggtcaa gacgcagcag     1440

ggagtgcctg cccagcccgc ggacttccag gccgaggtgg agtcggacac caggatccag     1500

ctctcgtggc tgctgccccc tcaggagcgg atcatcatgt atgaactggt gtactgggcg     1560

gcagaggacg aagaccaaca gcacaaggtg accttcgacc caacctcctc ctacacacta     1620

gaggacctga agcctgacac actctaccgc ttccagctgg ctgcacgctc ggatatgggg     1680

gtgggcgtct tcacccccac cattgaggcc cgcacagccc agtccacccc ctccgcccct     1740

ccccagaagg tgatgtgtgt gagcatgggc tccaccacgg tccgggtaag ttgggtcccg     1800

ccgcctgccg acagccgcaa cggcgttatc acccagtact ccgtggccta cgaggcggtg     1860

gacggcgagg accgcgggcg gcatgtggtg gatggcatca gccgtgagca ctccagctgg     1920

gacctggtgg gcctggagaa gtggacggag taccgggtgt gggtgcgggc acacacagac     1980

gtgggccccg gccccgagag cagcccggtg ctggtgcgca ccgatgagga cgtgcccagc     2040

gggcctccgc ggaaggtgga ggtggagcca ctgaactcca ctgctgtgca tgtctactgg     2100

aagctgcctg tccccagcaa gcagcatggc cagatccgcg gctaccaggt cacctacgtg     2160

cggctggaga atggcgagcc ccgtggactc cccatcatcc aagacgtcat gctagccgag     2220

gcccaggaaa ccactatcag cggcctgacc ccggagacca cctactccgt tactgttgct     2280

gcctatacca ccaaggggga tggtgcccgc agcaagccca aaattgtcac tacaacaggt     2340

gcagtcccag gccggcccac catgatgatc agcaccacgg ccatgaacac tgcgctgctc     2400

cagtggcacc cacccaagga actgcctggc gagctgctgg gctaccggct gcagtactgc     2460

cgggccgacg aggcgcggcc caacaccata gatttcggca aggatgacca gcacttcaca     2520

gtcaccggcc tgcacaaggg gaccacctac atcttccggc ttgctgccaa gaaccgggct     2580

ggcttgggtg aggagttcga gaaggagatc aggacccccg aggacctgcc cagcggcttc     2640

ccccaaaacc tgcatgtgac aggactgacc acgtctacca cagaactggc ctgggacccg     2700

ccagtgctgg cggagaggaa cgggcgcatc atcagctaca ccgtggtgtt ccgagacatc     2760

aacagccaac aggagctgca gaacatcacg acagacaccc gctttaccct tactggcctc     2820

aagccagaca ccacttacga catcaaggtc cgcgcatgga ccagcaaagg ctctggccca     2880

ctcagcccca gcatccagtc ccggaccatg ccggtggagc aagtgtttgc caagaacttc     2940

cgggtggcgg ctgcaatgaa gacgtctgtg ctgctcagct gggaggttcc cgactcctat     3000

aagtcagctg tgccctttaa gattctgtac aatgggcaga gtgtggaggt ggacgggcac     3060

tcgatgcgga agctgatcgc agacctgcag cccaacacag agtactcgtt tgtgctgatg     3120

aaccgtggca gcagcgcagg gggcctgcag cacctggtgt ccatccgcac agcccccgac     3180

ctcctgcctc acaagccgct gcctgcctct gcctacatag aggacggccg cttcgatctc     3240

tccatgcccc atgtgcaaga cccctcgctt gtcaggtggt tctacattgt tgtggtgccc     3300

attgaccgtg tgggcgggag catgctgacg ccaaggtgga gcacacccga ggaactggag     3360

ctggacgagc ttctagaagc catcgagcaa ggcggagagg agcagcggcg gcggcggcgg     3420

caggcagaac gtctgaagcc atatgtggct gctcaactgg atgtgctccc ggagaccttt     3480

accttggggg acaagaagaa ctaccggggc ttctacaacc ggcccctgtc tccggacttg     3540

agctaccagt gctttgtgct tgcctccttg aaggaaccca tggaccagaa gcgctatgcc     3600

tccagcccct actcggatga gatcgtggtc caggtgacac cagcccagca gcaggaggag     3660

ccggagatgc tgtgg                                                      3675


<210>  4219
<211>  2151
<212>  DNA
<213>  Homo Sapiens

<400>  4219
gtgctccatt atgtcgtgtg cttccccgcg ttgacagaag gctacgttgg ggccctgcac       60

gagaatagac acggcagcgc agtgcagatc cgcaggcgca aggcttcagg cgacccgtac      120

tgggcctact ctggtgccta tggtcctgag cactgggtca cgtctagtgt cagctgtggg      180

ggccgtcacc agtctcctat tgacatttta gaccagcatg cgcgtgttgg ggaagaatac      240

caggaactgc aactcgatgg cttcgacaat gagtcttcta acaaaacctg gatgaaaaac      300

acagggaaaa cagtcgccat ccttctgaaa gacgactatt ttgtcagtgg agctggtcta      360

cctggcagat tcaaagctga gaaggtggaa tttcactggg gccacagcaa tggctcagcg      420

ggctctgaac acagcatcaa tggcaggagg tttcctgttg agatgcagat tttcttttac      480

aatccagatg actttgacag ctttcaaacc gcaatttctg agaacagaat aatcggagcc      540

atggccatat tttttcaagt cagtccgagg gacaattctg cactggatcc tattatccac      600

gggttgaagg gtgtcgtaca tcatgagaag gagacctttc tggatccttt cgtcctccgg      660

gacctcctgc ctgcatccct gggcagctat tatcggtaca caggttcctt gaccacacca      720

ccgtgtagcg aaatagtgga gtggatagtc ttccggagac ccgtccccat ctcttaccat      780

cagcttgagg ctttttattc catcttcacc acggagcagc aagaccatgt caagtcggtg      840

gagtatctga gaaataactt tcgaccacag cagcgtctgc atgacagggt ggtgtccaag      900

tccgccgtcc gtgactcctg gaaccacgac atgacagact tcttagaaaa cccactgggg      960

acagaagcct ctaaagtttg cagctctcca cccatccaca tgaaggtgca gcctctgaac     1020

cagacggcac tgcaggtgtc ctggagccag ccggagacta tctaccaccc acccatcatg     1080

aactacatga tctcctacag ctggaccaag aatgaggacg agaaggagaa gacgtttaca     1140

aaggacagcg acaaagactt gaaagccacc attagccatg tctcacccga tagcctttac     1200

ctgttccgag tccaggccgt gtgtcggaac gacatgcgca gcgactttag ccagacgatg     1260

ctgtttcaag ctaataccac tcgaatattc caagggacca gaatagtgaa aacaggagtg     1320

cccacagcgt ctcctgcctc ttcagccgac atggccccca tcagctcggg gtcttctacc     1380

tggacgtcct ctggcatccc attctcattt gtttccatgg caactgggat gggcccctcc     1440

tccagtggca gccaggccac agtggcctcg gtggtcacca gcacgctgct cgccggcctg     1500

gggttcggcg gtggtggcat ctcctctttc cccagcactg tgtggcccac gcgcctcccg     1560

acggccgcct cagccagcaa gcaggcggct aggccagtcc tagccaccac agaggccttg     1620

gcttctccag ggcccgatgg tgattcgtca ccaaccaagg acggcgaggg caccgaggaa     1680

ggagagaagg atgagaaaag cgagagtgag gatggggagc gggagcacga ggaggatgga     1740

gagaaggact ccgaaaagaa ggagaagagt ggggtgaccc acgctgccga ggagcggaat     1800

cagacggagc ccagccccac accctcgtct cctaacagga ctgccgaggg agggcatcag     1860

actatacctg ggcatgagca ggatcacact gccgtcccca cagaccagac gggcggaagg     1920

agggatgccg gcccaggcct ggaccccgac atggtcacct ccacccaagt gccccccacc     1980

gccacagagg agcagtatgc agggagtgat cccaagaggc ccgaaatgcc atctaaaaag     2040

cctatgtccc gcggggaccg attttctgaa gacagcagat ttatcactgt taatccagcg     2100

gaaaaaaaca cctctggaat gataagccgc cctgctccag ggaggatgga g              2151


<210>  4220
<211>  2181
<212>  DNA
<213>  Homo Sapiens

<400>  4220
cctgccccca acccagggag gaacctgaca gtggagactc agaccaccag ctccatctcc       60

ctgagctggg aggtccccga tggcctagac tcacagaact ccaactactg ggttcagtgt      120

actggagacg gcggcacaac agagactcga aacacaacag ccaccaacgt caccgtggat      180

ggccttggac ccgggtcatt gtatacgtgt tctgtgtggg tggagaaaga cggagtaaat      240

agctctgtgg ggactgtcac tactgccaca gctcccaacc cagtgaggaa cctgagagtg      300

gaggctcaga ccaacagctc catcgccctg acctgggagg tccccgacgg cccagaccca      360

cagaactcca cctacggggt tgagtacact ggagatggtg gcagagcagg gactcgaagc      420

acagcacaca ccaacatcac cgtggatgga cttgaacccg ggtgtttgta tgcgttttcc      480

atgtgggtgg gaaagaatgg aatcaacagc tcccgggaga ctcgaaatgc caccacagct      540

cacaacccag tgaggaacct gagagtggag gctcagacca ccagctccat ctccctgagc      600

tgggaggtcc ccgatggcac agacccacag aactccacct actgcgttca gtgcactgga      660

gatggtggca gaacagagac tcgaaacaca acagacacca gagtcaccgt ggatggcctt      720

ggacccgggt cattgtatac gtgttctgtg tgggtggaga aagacggagt aaatagctct      780

gtggagattg tcactagtgc cacagctccc aacccagtga gaaacctgac agtggaggct      840

cagaccaaca gctccatcgc cctgacctgg gaggtccccg atggcccaga cccacagaac      900

tccacctacg gggttgagta cactggagat ggtggcagag cagggactcg aagcacagca      960

tacaccaaca tcaccgtgga tagacttgaa cccgggtgtt tgtatgtgtt ttccgtgtgg     1020

gtggggaaga atggaatcaa cagctcccgg gagactcgaa atgccaccac agcccccaac     1080

ccagtgagaa acctccatat ggagactcag accaacagct ccatcgccct atgctgggaa     1140

gtccccgatg gcccataccc tcaggactac acctactggg tagagtacac tggagacggt     1200

ggtggcacag agacccgaaa cacaacaaat accagtgtga cagctgagag acttgagccc     1260

ggaaccttgt acacattctc tgtatgggca gaaaaaaatg gagcacgtgg ctccaggcag     1320

aatgtcagca tctccacagt ccccaacgca gtgacaagcc tcagcaagca ggactggacc     1380

aacagcacca ttgctttgcg ctggacagct ccccagggcc caggccagtc ttcctacagc     1440

tactgggtct catgggtcag ggaaggcatg actgacccca ggacccaaag cacctcaggt     1500

actgacatca ccctaaagga actggaagct ggcagcctgt accacctcac cgtctgggcc     1560

gagaggaatg aggtcagagg ctataacagc accctcactg cagccactgc tcccaatgag     1620

gtcacagatc tccagaatga aactcagact aagaactcag tcatgctgtg gtggaaggcc     1680

cctggagacc cccactctca gttgtacgta tactgggtcc agtgggccag caagggacat     1740

ccccggaggg ggcaagatcc ccaagcgaat tgggtcaacc agaccagcag gaccaatgag     1800

acgtggtaca aagtggaggc cctggaaccc gggacgctgt acaatttcac cgtgtgggca     1860

gagaggaatg acgtagccag ttccacgcag agcctctgtg cgtccacata cccagacaca     1920

gtcaccatca cttcctgtgt cagcacctca gcgggctatg gagtcaactt gatctggtcc     1980

tgcccccagg gaggctacga ggcctttgag ttggaggtgg gaggacagcg gggctcccag     2040

gacagatctt catgtgggga ggctgtgtct gtgttgggtc tcgggccggc tcggtcctac     2100

ccagccacca tcacgaccat ctgggacgga atgaaggtcg tgtctcactc tgtggtctgc     2160

cacaccgaga gtgcaggggt c                                               2181


<210>  4221
<211>  1512
<212>  DNA
<213>  Homo Sapiens

<400>  4221
gcaggtggca cccctagtcc aattcctgac ccttcagtag caactgttgc cacaggggaa       60

aatggcataa cgcagatcag cagtacagca gaatcctttc ataaacagaa tggaactgga      120

acacctcagg tggaaacaaa caccagtgag gatggtgaaa gctctggagc caacgatagt      180

ttaagaacac ctgaacaagg atctaatggg actgatgggg catctcaaaa aactcccagt      240

agcactgggc ccagtcctgt gtttgacatt aaagctgttt ccatcagtcc aaccaatgtg      300

atcttaactt ggaaaagtaa tgacacagct gcttctgagt acaagtatgt agtaaagcat      360

aagatggaaa atgagaagac aattactgtt gtgcatcaac catggtgtaa catcacaggc      420

ttacgtccag cgacttcata tgtattctcc atcactccag gaataggcaa tgagacttgg      480

ggagatccca gagtcataaa agtcatcaca gagccgatcc cagtttctga tctccgtgtt      540

gccctcacgg gtgtgaggaa ggctgctctc tcctggagca atggcaatgg caccgcctcc      600

tgccgggttc ttcttgaaag cattggaagc catgaggagt tgactcaaga ctcaagactt      660

caggtcaata tctcgggcct gaagccaggg gttcaataca acatcaaccc gtatcttcta      720

caatcaaata agacaaaggg agaccccttg ggcacagaag gtggcttgga tgccagcaat      780

acagagagaa gccgggcagg gagccccacc gcccctgtgc atgatgagtc cctcgtggga      840

cctgtggacc catcctccgg ccagcagtcc cgagacacgg aagtcctgct tgtcgggtta      900

gagcctggca cccgatacaa tgccaccgtt tattcccaag cagcgaatgg cacagaagga      960

cagccccagg ccatagagtt caggacaaat gctattcagg tttttgacgt caccgctgtg     1020

aacatcagtg ccacaagcct gaccctgatc tggaaagtca gcgataacga gtcgtcatct     1080

aactatacct acaagataca tgtggcgggg gagacagatt cttccaatct caacgtcagt     1140

gagcctcgcg ctgtcatccc cggactccgc tccagcacct tctacaacat cacagtgtgt     1200

cctgtcctag gtgacatcga gggcacgccg ggcttcctcc aagtgcacac cccccctgtt     1260

ccagtttctg acttccgagt gacagtggtc agcacgacgg agatcggctt agcatggagc     1320

agccatgatg cagaatcatt tcagatgcat atcacacagg agggagctgg caattctcgg     1380

gtagaaataa ccaccaacca aagtattatc attggtggct tgttccctgg aaccaagtat     1440

tgctttgaaa tagttccaaa aggaccaaat gggactgaag gggcatctcg gacagtttgc     1500

aatagaactg ga                                                         1512


<210>  4222
<211>  2181
<212>  DNA
<213>  Homo Sapiens

<400>  4222
gcccaaggcc agttctccgc aggtggctgt acttttgatg atggtccagg ggcctgtgat       60

taccaccagg atctgtatga tgactttgaa tgggtgcatg ttagtgctca agagcctcat      120

tatctaccac ccgagatgcc ccaaggttcc tatatgatag tggactcttc agatcacgac      180

cctggagaaa aagccagact tcagctgcct acaatgaagg agaacgacac tcactgcatt      240

gatttcagtt acctattata tagccagaaa ggactgaatc ctggcacttt gaacatatta      300

gttagggtga ataaaggacc tcttgccaat ccaatttgga atgtgactgg attcacgggt      360

agagattggc ttcgggctga gctagcagtg agcacctttt ggcccaatga atatcaggta      420

atatttgaag ctgaagtctc aggagggaga agtggttata ttgccattga tgacatccaa      480

gtactgagtt atccttgtga taaatctcct catttcctcc gtctagggga tgtagaggtg      540

aatgcagggc aaaacgctac atttcagtgc attgccacag ggagagatgc tgtgcataac      600

aagttatggc tccagagacg aaatggagaa gatataccag tagcccagac taagaacatc      660

aatcatagaa ggtttgccgc ttccttcaga ttgcaagaag tgacaaaaac tgaccaggat      720

ttgtatcgct gtgtaactca gtcagaacga ggttccggtg tgtccaattt tgctcaactt      780

attgtgagag aaccgccaag acccattgct cctcctcagc ttcttggtgt tgggcctaca      840

tatttgctga tccaactaaa tgccaactcg atcattggcg atggtcctat catcctgaaa      900

gaagtagagt accgaatgac atcaggatcc tggacagaaa cccatgcagt caatgctcca      960

acttacaaat tatggcattt agatccagat accgaatatg agatccgagt tctacttaca     1020

agacctggtg aaggtggaac ggggctccca ggacctccac taatcaccag aacaaaatgt     1080

gcagaaccta tgagaacccc aaagacatta aagattgctg aaatacaggc aagacggatt     1140

gctgtggact gggaatcctt gggttacaac attacgcgtt gccacacttt taatgtcact     1200

atctgctacc attacttccg tggtcacaac gagagcaagg cagactgttt ggacatggac     1260

cccaaagccc ctcagcatgt tgtgaaccat ctgccacctt atacaaatgt cagcctcaag     1320

atgatcctaa ccaatccaga gggaaggaag gagagtgaag agacaattat tcaaactgat     1380

gaagatgtgc ctggtcccgt accagtaaaa tctcttcaag gaacatcctt tgaaaataag     1440

atcttcttga actggaaaga acctttggat ccaaatggaa tcatcactca atatgagatc     1500

agctatagca gtataagatc atttgatcct gcagttccag tggctggacc tccccagact     1560

gtatcaaatt tatggaacag tacacaccat gtctttatgc atctccaccc tggaaccacg     1620

taccagtttt tcataagagc cagcacggtc aaaggctttg gtccagccac agccatcaat     1680

gtcaccacca atatctcagc tccaacttta cctgactatg aaggagttga tgcctctctc     1740

aatgaaactg ccaccacaat aactgtattg ttgagaccag cacaagccaa aggtgctcct     1800

atcagtgctt atcagattgt tgtggaagaa ctgcacccac accgaaccaa gagagaagcc     1860

ggagccatgg aatgctacca ggttcctgtc acataccaaa atgccatgag tgggggtgca     1920

ccgtattact ttgctgcaga actacccccg ggaaacctac ctgagcctgc cccgttcact     1980

gtgggtgaca atcggaccta ccaaggcttt tggaaccctc ctttggctcc gcgcaaagga     2040

tacaacatct atttccaggc gatgagcagt gtggagaagg aaactaaaac ccagtgcgta     2100

cgcattgcta caaaagcagc agcaacagaa gaaccagaag tgatcccaga tcccgccaag     2160

cagacagaca gagtggtgaa a                                               2181


<210>  4223
<211>  1536
<212>  DNA
<213>  Homo Sapiens

<400>  4223
gttagtgccc acggctgtct atttgaccgc aggctctgct ctcacctgga agtctgtatt       60

caggatggct tgtttgggca gtgccaggtg ggagtggggc aggcccggcc ccttttgcaa      120

gtcacctccc cagttctcca acgcttacaa ggtgtgctcc gacaactcat gtcccaagga      180

ttgtcctggc acgatgacct cacccagtat gtgatctctc aggagatgga gcgcatcccc      240

aggcttcgcc ccccagagcc ccgtccaagg gacaggtctg gcttggcacc caagagacct      300

ggtcctgctg gagagctgct tttacaggac atccccactg gctccgcccc tgctgcccag      360

catcggcttc cacaaccacc agtgggcaaa ggtggagctg gggccagctc ctctctgtcc      420

cctctgcagg ctgagctgct cccgcctctc ttggagcacc tgctgctgcc cccacagcct      480

ccccaccctt cactgagtta cgaacctgcc ttgctgcagc cctacctgtt ccaccagttt      540

ggctcccgtg atggctccag ggtctcagag ggctccccag ggatggtcag tgtcggcccc      600

ctgcccaagg ctgaagcccc tgccctcttc agcagaactg cctccaaggg catatttggg      660

gaccaccctg gccactccta cggggacctt ccagggcctt cacctgccca gctttttcaa      720

gactctgggc tgctctatct ggcccaggag ttgccagcac ccagcagggc cagggtgcca      780

aggctgccag agcaagggag cagcagccgg gcagaggact ccccagaggg ctatgagaag      840

gaaggactag gggatcgtgg agagaagcct gcttccccag ctgtgcagcc agatgcggct      900

ctgcagaggc tggccgctgt gctggcgggc tatggggtag agctgcgtca gctgacccct      960

gagcagctct ccacactcct gaccctgctg cagctactgc ccaagggtgc aggaagaaat     1020

ccgggagggg ttgtaaatgt tggagctgat atcaagaaaa caatggaggg gccggtggag     1080

ggcagagaca cagcagagct tccagcccgc acatccccca tgcctggaca ccccactgcc     1140

agccctacct ccagtgaagt ccagcaggtg ccaagccctg tctcctctga gcctcccaaa     1200

gctgccagac cccctgtgac acctgtcctg ctagagaaga aaagcccact gggccagagc     1260

cagcccacgg tggcaggaca gccctcagcc cgcccagcag cagaggaata tggctacatc     1320

gtcactgatc agaatgtggt gggaccagcc ctcaccttcc gcatccggca caatgagcag     1380

aacctgtctt tggctgatgt gacccaacaa gcagggctgg tgaagtctga actggaagca     1440

cagacagggc tccaaatctt gcagacagga gtgggacaga gggaggaggc agctgcagtc     1500

cttccccaaa ctgcgcacag cacctcaccc atgcgc                               1536


<210>  4224
<211>  2379
<212>  DNA
<213>  Homo Sapiens

<400>  4224
ttccatgtaa ctgtccaaga tgataataac atcgttgtct cattagaagc ttcagacgtc       60

atcagtccag catctgtgta tgttgtgaag ataactggtg aatccaaaaa ttatttcttc      120

gaatttgagg aattcaacag cactttgcct cctcctgtta ttttcaaggc cagttatcat      180

ggcctttatt atataatcac tctggtagtg gtaaatggaa atgtggtgac caagccatcc      240

agatcaatca ctgtgttaac aaaacctcta cctgtaacca gtgtttccat atatgactat      300

aaaccttctc ctgaaacagg agtcctgttt gaaatacatt atccagaaaa atataacgtt      360

ttcacaagag tgaacattag ctactgggaa ggtaaagact tccggacaat gctatataaa      420

gatttcttta agggaaaaac agtatttaat cactggctgc caggaatgtg ttatagtaat      480

atcacctttc agctggtatc tgaggcaact tttaataaaa gtacccttgt tgagtacagt      540

ggtgtcagtc acgaacccaa acagcacaga actgcccctt atccacctca aaatatttcc      600

gttcgtatcg taaacttgaa caaaaacaac tgggaagaac agagtggcaa tttcccagaa      660

gaatccttca tgagatcaca agatacaata ggaaaagaaa aactcttcca ttttacagaa      720

gaaacccctg aaattccctc gggcaacatt tcttccggtt ggcctgattt taatagcagt      780

gactatgaaa ctacgtctca gccatattgg tgggacagtg catctgcagc tcctgaaagt      840

gaagatgaat ttgtcagcgt acttcccatg gaatacgaaa ataacagtac actcagtgag      900

acagagaagt caacatcagg ctctttctcc tttttccctg tgcaaatgat attgacctgg      960

ttaccaccca aaccacccac tgcttttgat gggttccata tccatattga acgagaagag     1020

aactttactg aatatttgat ggtggatgaa gaagcacatg aatttgttgc agaactgaag     1080

gaacctggga aatataagtt atctgtgaca acctttagtt cctcaggatc ttgtgaaact     1140

cgaaaaagtc agtcagcaaa atcactcagc ttttatatca gtccttcagg agagtggatt     1200

gaagaactga ccgagaagcc gcagcacgtg agtgtccacg ttttaagctc aaccactgcc     1260

ttgatgtcct ggacatcttc ccaagagaac tacaacagca ccattgtgtc tgtggtgtcg     1320

ctgacctgcc agaaacaaaa ggagagccag aggcttgaaa agcagtactg cactcaggtg     1380

aactcaagca aacctattat tgaaaatctg gttcctggtg cccagtacca ggttgtaata     1440

tacctaagga aaggcccttt gattggacca ccttcagatc ctgtgacatt tgctattgtt     1500

cccacaggaa taaaggattt aatgctctat cctttgggtc ctacggccgt ggttctgagc     1560

tggaccagac cttatttagg cgtgttcaga aaatacgtgg ttgaaatgtt ttatttcaac     1620

cctgctacaa tgacatcaga gtggaccacc tactatgaaa tagcagcaac tgtttcctta     1680

actgcatccg tgagaatagc taatctgctg ccagcatggt actacaactt ccgggttacc     1740

atggtgacgt ggggagatcc agaattgagc tgctgtgaca gctctaccat cagcttcata     1800

acagccccag tggctccgga aatcacttct gtggaatatt tcaacagtct gttatatatc     1860

agttggacat atggggatga tacaacggac ttgtcccatt ctagaatgct tcactggatg     1920

gtggttgcag aaggaaaaaa gaaaattaaa aagagtgtaa cacgcaatgt catgactgca     1980

attctcagct tgcctccagg cgacatctat aacctctcag taactgcttg tactgaaaga     2040

ggaagtaata cctccatgct ccgccttgtc aagctagaac cagctccacc caaatcactc     2100

ttcgcagtga acaaaaccca gacttcagtg actttgctgt gggtggaaga gggagtagct     2160

gatttctttg aagttttctg tcaacaagtt ggctccagtc agaaaaccaa acttcaggaa     2220

ccagttgctg tttcttccca tgtcgtgacc atctccagcc ttcttcctgc cactgcctac     2280

aattgtagtg tcaccagctt tagccatgac agccccagtg tccctacgtt catagccgtc     2340

tcaacaatgg ttacagagat gaatcccaat gtggtagtg                            2379


<210>  4225
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  4225
tttagcggta ataacgatca tttcctagct atcaatcaga agaagtctgg gaagccagtg       60

tttatctata aacacagtca ggatattgag aagtccttgg atattgctcc gcaaaagata      120

tataggcact cataccactc tagctctgaa gctcaggtgt ccaagagaca ccagatagtg      180

aactctgcct tccctaggcc ggcatacgac ccaagcctta accttctggc aatggatggg      240

caggacttgg aggtggaaaa cctacctatt cctgctgcaa acgtgattgt ggttacgcta      300

cagatggatg ttaataaact gaatatcacg ctgctaagga tctttcgtca gggggtggca      360

gccgcactgg gcttactgcc tcagcaggta catattaatc gtctgatcgg caagaaaaac      420

tctatagagc tatttgtgag tccgatcaat agaaaaactg gcatctccga tgccctgcct      480

agtgaagaag ttcttaggtc acttaacata aatgttttac atcaatctct atcacaattt      540

ggtataactg aggtatctcc agaaaagaat gtgctgcaag gtcaacacga agccgacaag      600

atatggtcta aagagggt                                                    618


<210>  4226
<211>  2466
<212>  DNA
<213>  Homo Sapiens

<400>  4226
gaagagcccc ccaggtttat caaagaaccc aaggaccaga tcggcgtgtc ggggggtgtg       60

gcctctttcg tgtgtcaggc cacgggtgac cccaagccac gagtgacctg gaacaagaag      120

ggcaagaagg tcaactctca gcgctttgag acgattgagt ttgatgagag tgcaggggca      180

gtgctgagga tccagccgct gaggacaccg cgggatgaaa acgtgtacga gtgtgtggcc      240

cagaactcgg ttggggagat cacagtccat gccaagctta ctgtcctccg agaggaccag      300

ctgccctctg gcttccccaa catcgacatg ggcccacagt tgaaggtggt ggagcggaca      360

cggacagcca ccatgctctg tgcagccagc ggcaaccctg accctgagat cacctggttc      420

aaggacttcc tgcctgtgga tcctagtgcc agcaatggac gcatcaaaca gctgcgatca      480

ggagccctgc agattgaaag cagtgaggaa accgaccagg gcaaatatga gtgtgtggcc      540

accaacagcg ccggcgtgcg ctactcctca cctgccaacc tctacgtgcg agtccgccgc      600

gtggccccgc gcttctccat cctgcccatg agccacgaga tcatgccagg gggcaacgtg      660

aacatcacct gcgtggccgt gggctcgccc atgccatacg tgaagtggat gcagggggcc      720

gaggacctga cccccgagga tgacatgccc gtgggtcgga acgtgctgga actcacagat      780

gtcaaggact cggccaacta cacctgcgtg gccatgtcca gcctgggcgt cattgaggcg      840

gttgctcaga tcacggtgaa atctctcccc aaagctcccg ggactcccat ggtgactgag      900

aacacagcca ccagcatcac catcacgtgg gactcgggca acccagatcc tgtgtcctat      960

tacgtcatcg aatataaatc caagagccaa gacgggccgt atcagattaa agaggacatc     1020

accaccacac gttacagcat cggcggcctg agccccaact cggagtacga gatctgggtg     1080

tcggccgtca actccatcgg ccaggggccc cccagcgagt ccgtggtcac ccgcacaggc     1140

gagcaggccc cggccagcgc gccgcggaac gtgcaagccc ggatgctcag cgcgaccacc     1200

atgattgtgc agtgggagga gccggtggag cccaacggcc tgatccgcgg ctaccgcgtc     1260

tactacacca tggaaccgga gcaccccgtg ggcaactggc agaagcacaa cgtggacgac     1320

agcctgctga ccaccgtggg cagcctgctg gaggacgaga cctacaccgt gcgggtgctc     1380

gccttcacct ccgtcggcga cgggcccctc tcggacccca tccaggtcaa gacgcagcag     1440

ggagtgccgg gccagcccat gaacctgcgg gccgaggcca ggtcggagac cagcatcacg     1500

ctgtcctgga gccccccgcg gcaggagagt atcatcaagt acgagctcct cttccgggaa     1560

ggcgaccatg gccgggaggt gggaaggacc ttcgacccga cgacttccta cgtggtggag     1620

gacctgaagc ccaacacgga gtacgccttc cgcctggcgg cccgctcgcc gcagggcctg     1680

ggcgccttca cccccgtggt gcggcagcgc acgctgcagt ccatctcgcc caagaacttc     1740

aaggtgaaaa tgatcatgaa gacatcagtt ctgctcagct gggagttccc tgacaactac     1800

aactcaccca caccctacaa gatccagtac aatgggctca cactggatgt ggatggccgt     1860

accaccaaga agctcatcac gcacctcaag ccccacacct tctacaactt tgtgctgacc     1920

aatcgcggca gcagcctggg cggcctccag cagacggtca ccgcctggac tgccttcaac     1980

ctgctcaacg gcaagcccag cgtcgccccc aagcctgatg ctgacggctt catcatggtg     2040

tatcttcctg acggccagag ccccgtgcct gtccagagct atttcattgt gatggtgcca     2100

ctgcgcaagt ctcgtggagg ccaattcctg accccgctgg gtagcccaga ggacatggat     2160

ctggaagagc tcatccagga catctcacgg ctacagaggc gcagcctgcg gcactcgcgt     2220

cagctggagg tgccccggcc ctatattgca gctcgcttct ctgtgctgcc acccacgttc     2280

catcccggcg accagaagca gtatggcggc ttcgataacc ggggcctgga gcccggccac     2340

cgctatgtcc tcttcgtgct tgccgtgctt cagaagagcg agcctacctt tgcagccagt     2400

cccttctcag accccttcca gctggataac ccggaccccc agcccatcgt ggatggcgag     2460

gagggg                                                                2466


<210>  4227
<211>  1092
<212>  DNA
<213>  Homo Sapiens

<400>  4227
gagaactcgg atgattatga tctcatgtat gtgaatttgg acaacgaaat agacaatgga       60

ctccatccca ctgaggaccc cacgccgtgc gactgcggtc aggagcactc ggaatgggac      120

aagctcttca tcatgctgga gaactcgcag atgagagagc gcatgctgct gcaagccacg      180

gacgacgtcc tgcggggcga gctgcagagg ctgcgggagg agctgggccg gctcgcggaa      240

agcctggcga ggccgtgcgc gccgggggct cccgcagagg ccaggctgac cagtgctctg      300

gacgagctgc tgcaggcgac ccgcgacgcg ggccgcaggc tggcgcgtat ggagggcgcg      360

gaggcgcagc gcccagagga ggcggggcgc gccctggccg cggtgctaga ggagctgcgg      420

cagacgcgag ccgacctgca cgcggtgcag ggctgggctg cccggagctg gctgccggca      480

ggttgtgaaa cagctatttt attcccaatg cgttccaaga agatttttgg aagcgtgcat      540

ccagtgagac caatgaggct tgagtctttt agtgcctgca tttgggtcaa agccacagat      600

gtattaaaca aaaccatcct gttttcctat ggcacaaaga ggaatccata tgaaatccag      660

ctgtatctca gctaccaatc catagtgttt gtggtgggtg gagaggagaa caaactggtt      720

gctgaagcca tggtttccct gggaaggtgg acccacctgt gcggcacctg gaattcagag      780

gaagggctca catccttgtg ggtaaatggt gaactggcgg ctaccactgt tgagatggcc      840

acaggtcaca ttgttcctga gggaggaatc ctgcagattg gccaagaaaa gaatggctgc      900

tgtgtgggtg gtggctttga tgaaacatta gccttctctg ggagactcac aggcttcaat      960

atctgggata gtgttcttag caatgaagag ataagagaga ccggaggagc agagtcttgt     1020

cacatccggg ggaatattgt tgggtgggga gtcacagaga tccagccaca tggaggagct     1080

cagtatgttt ca                                                         1092


<210>  4228
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  4228
tggccacccc caggaaccgg ggacgtcgtc gtgcaggcgc ccacccaggt gcccggcttc       60

ttgggcgact ccgtgacgct gccctgctac ctacaggtgc ccaacatgga ggtgacgcat      120

gtgtcacagc tgacttgggc gcggcatggt gaatctggca gcatggccgt cttccaccaa      180

acgcagggcc ccagctattc ggagtccaaa cggctggaat tcgtggcagc cagactgggc      240

gcggagctgc ggaatgcctc gctgaggatg ttcgggttgc gcgtagagga tgaaggcaac      300

tacacctgcc tgttcgtcac gttcccgcag ggcagcagga gcgtggatat ctggctccga      360

gtgcttgcca agccccagaa cacagctgag gttcagaagg tccagctcac tggagagcca      420

gtgcccatgg cccgctgcgt ctccacaggg ggtcgcccgc cagcccaaat cacctggcac      480

tcagacctgg gcgggatgcc caatacgagc caggtgccag ggttcctgtc tggcacagtc      540

actgtcacca gcctctggat attggtgccc tcaagccagg tggacggcaa gaatgtgacc      600

tgcaaggtgg agcacgagag ctttgagaag cctcagctgc tgactgtgaa cctcaccgtg      660

tactaccccc cagaggtatc catctctggc tatgataaca actggtacct tggccagaat      720

gaggccaccc tgacctgcga tgctcgcagc aacccagagc ccacaggcta taattggagc      780

acgaccatgg gtcccctgcc accctttgct gtggcccagg gcgcccagct cctgatccgt      840

cctgtggaca aaccaatcaa cacaacttta atctgcaacg tcaccaatgc cctaggagct      900

cgccaggcag aactgaccgt ccaggtcaaa gagggacctc ccagtgagca ctcaggcatg      960

tcccgtaac                                                              969


<210>  4229
<211>  975
<212>  DNA
<213>  Homo Sapiens

<400>  4229
caggtggtcc aggtgaacga ctccatgtat ggcttcatcg gcacagacgt ggttctgcac       60

tgcagctttg ccaacccgct tcccagcgtg aagatcaccc aggtcacatg gcagaagtcc      120

accaatggct ccaagcagaa cgtggccatc tacaacccat ccatgggcgt gtccgtgctg      180

gctccctacc gcgagcgtgt ggaattcctg cggccctcct tcaccgatgg cactatccgc      240

ctctcccgcc tggagctgga ggatgagggt gtctacatct gcgagtttgc taccttccct      300

acgggcaatc gagaaagcca gctcaatctc acggtgatgg ccaaacccac caattggata      360

gagggtaccc aggcagtgct tcgagccaag aaggggcagg atgacaaggt cctggtggcc      420

acctgcacct cagccaatgg gaagcctccc agtgtggtat cctgggaaac tcggttaaaa      480

ggtgaggcag agtaccagga gatccggaac cccaatggca cagtgacggt catcagccgc      540

taccgcctgg tgcccagcag ggaagcccac cagcagtcct tggcctgcat cgtcaactac      600

cacatggacc gcttcaagga aagcctcact ctcaacgtgc agtatgagcc tgaggtaacc      660

attgaggggt ttgatggcaa ctggtacctg cagcggatgg acgtgaagct cacctgcaaa      720

gctgatgcta accccccagc cactgagtac cactggacca cgctaaatgg ctctctcccc      780

aagggtgtgg aggcccagaa cagaaccctc ttcttcaagg gacccatcaa ctacagcctg      840

gcagggacct acatctgtga ggccaccaac cccatcggta cacgctcagg ccaggtggag      900

gtcaatatca cagaattccc ctacaccccg tctcctcccg aacatgggcg gcgcgccggg      960

ccggtgccca cggcc                                                       975


<210>  4230
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  4230
caggatgtgc gagttcaagt gctacccgag gtgcgaggcc agctcggggg caccgtggag       60

ctgccgtgcc acctgctgcc acctgttcct ggactgtaca tctccctggt gacctggcag      120

cgcccagatg cacctgcgaa ccaccagaat gtggccgcct tccaccctaa gatgggtccc      180

agcttcccca gcccgaagcc tggcagcgag cggctgtcct tcgtctctgc caagcagagc      240

actgggcaag acacagaggc agagctccag gacgccacgc tggccctcca cgggctcacg      300

gtggaggacg agggcaacta cacttgcgag tttgccacct tccccaaggg gtccgtccga      360

gggatgacct ggctcagagt catagccaag cccaagaacc aagctgaggc ccagaaggtc      420

acgttcagcc aggaccctac gacagtggcc ctctgcatct ccaaagaggg ccgcccacct      480

gcccggatct cctggctctc atccctggac tgggaagcca aagagactca ggtgtcaggg      540

accctggccg gaactgtcac tgtcaccagc cgcttcacct tggtgccctc gggccgagca      600

gatggtgtca cggtcacctg caaagtggag catgagagct tcgaggaacc agccctgata      660

cctgtgaccc tctctgtacg ctaccctcct gaagtgtcca tctccggcta tgatgacaac      720

tggtacctcg gccgtactga tgccaccctg agctgtgacg tccgcagcaa cccagagccc      780

acgggctatg actggagcac gacctcaggc accttcccga cctccgcagt ggcccagggc      840

tcccagctgg tcatccacgc agtggacagt ctgttcaata ccaccttcgt ctgcacagtc      900

accaatgccg tgggcatggg ccgcgctgag caggtcatct ttgtccgaga aacccccagg      960

gcctcgcccc gagatgtggg cccgctg                                          987


<210>  4231
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  4231
ggaccaatta ttgtggagcc acatgtcaca gcagtatggg gaaagaatgt ttcattaaag       60

tgtttaattg aagtaaatga aaccataaca cagatttcat gggagaagat acatggcaaa      120

agttcacaga ctgttgcagt tcaccatccc caatatggat tctctgttca aggagaatat      180

cagggaagag tcttgtttaa aaattactca cttaatgatg caacaattac tctgcataac      240

ataggattct ctgattctgg aaaatacatc tgcaaagctg ttacattccc gcttggaaat      300

gcccagtcct ctacaactgt aactgtgtta gttgaaccca ctgtgagcct gataaaaggg      360

ccagattctt taattgatgg aggaaatgaa acagtagcag ccatttgcat cgcagccact      420

ggaaaacccg ttgcacatat tgactgggaa ggtgatcttg gtgaaatgga atccactaca      480

acttcttttc caaatgaaac ggcaacgatt atcagccagt acaagctatt tccaaccaga      540

tttgctagag gaaggcgaat tacttgtgtt gtaaaacatc aagccttgga aaaggacatc      600

cgatactctt tcatattaga catacagtat gctcctgaag tttcggtaac aggatatgat      660

ggaaattggt ttgtaggaag aaaaggtgtt aatctcaaat gtaatgctga tgcaaatcca      720

ccacccttca aatctgtgtg gagcaggttg gatggacaat ggcctgatgg tttattggct      780

tcagacaata ctcttcattt tgtccatcca ttgactttca attattctgg tgtttatatc      840

tgtaaagtga ccaattccct tggtcaaaga agtgaccaaa aagtcatcta catttcagcc      900

tacaattcag tggcatccct caactgc                                          927


<210>  4232
<211>  954
<212>  DNA
<213>  Homo Sapiens

<400>  4232
ggtgagctgg agacctcaga cgtggtaact gtggtgctgg gccaggacgc aaaactgccc       60

tgcttctacc gaggggactc cggcgagcaa gtggggcaag tggcatgggc tcgggtggac      120

gcgggcgaag gcgcccagga actagcgcta ctgcactcca aatacgggct tcatgtgagc      180

ccggcttacg agggccgcgt ggagcagccg ccgcccccac gcaaccccct ggacggctca      240

gtgctcctgc gcaacgcagt gcaggcggat gagggcgagt acgagtgccg ggtcagcacc      300

ttccccgccg gcagcttcca ggcgcggctg cggctccgag tgctggtgcc tcccctgccc      360

tcactgaatc ctggtccagc actagaagag ggccagggcc tgaccctggc agcctcctgc      420

acagctgagg gcagcccagc ccccagcgtg acctgggaca cggaggtcaa aggcacaacg      480

tccagccgtt ccttcaagca ctcccgctct gctgccgtca cctcagagtt ccacttggtg      540

cctagccgca gcatgaatgg gcagccactg acttgtgtgg tgtcccatcc tggcctgctc      600

caggaccaaa ggatcaccca catcctccac gtgtccttcc ttgctgaggc ctctgtgagg      660

ggccttgaag accaaaatct gtggcacatt ggcagagaag gagctatgct caagtgcctg      720

agtgaagggc agccccctcc ctcatacaac tggacacggc tggatgggcc tctgcccagt      780

ggggtacgag tggatgggga cactttgggc tttcccccac tgaccactga gcacagcggc      840

atctacgtct gccatgtcag caatgagttc tcctcaaggg attctcaggt cactgtggat      900

gttcttgacc cccaggaaga ctctgggaag caggtggacc tagtgtcagc ctcg            954


<210>  4233
<211>  3804
<212>  DNA
<213>  Homo Sapiens

<400>  4233
atgtctgaat cttatcggag aactactttt ccagtaagat tccgtgttgt ctccgtggat       60

gaaaattttc gccctcgaaa tgaactgatt ccactgatat accttgagaa cccaagaaga      120

aatcgaattg cacaatggca gagtctcaag ctagaagctg gcatcaatca gttgtccttt      180

cccctctcat cagagcccat tcagggctcc tacagggtgg tggtacagac agaatcaggt      240

ggaaggatac agcacccctt caccgtggag gaatttgtgc ttcccaagtt tgaggtcaaa      300

gttcaggtgc caaagataat cagtatcatg gatgaaaaag tgaacataac agtctgtgga      360

gaatacactt atgggaagcc tgtcccagga cttgcaactg tgagcctgtg tagaaaatta      420

tctcgtgttc ttaattgtga caagcaggag gtctgtgagg aattcagtca acagcttaac      480

agcaatggct gcatcaccca acaagtacac accaaaatgc tccagattac aaatacgggc      540

tttgaaatga agcttagagt ggaagccagg atcagagaag aggggacaga cctggaagtc      600

actgcaaaca ggatcagtga aatcacaaac attgtatcca aactcaaatt cgtgaaagtg      660

gattcacact ttagacaagg aatccccttt tttgcacagg tgcttctggt ggatggaaaa      720

ggtgtgccca tccccaataa actcttcttc atctctgtga atgacgccaa ttattactcc      780

aatgcaacca ccaatgagca gggtcttgca cagttttcaa tcaatactac cagtatctcg      840

gttaataaac tttttgtccg ggttttcact gtgcatccca acttgtgttt tcactattca      900

tgggtagcag aagaccacca gggcgctcag cacactgcaa atcgtgtttt ctccttaagt      960

ggaagttaca ttcacctgga gcctgtggct ggtaccctgc cctgtggcca cacggagact     1020

atcacggcac actatacact gaatagacag gccatgggag agttatcgga gctcagtttc     1080

cattacctga tcatggctaa gggagtcatc gtcagatctg gaacccacac tctgcctgtg     1140

gagtcaggag acatgaaagg cagttttgcc ttatccttcc ctgtggagtc agacgttgcc     1200

cccattgcac gaatgttcat ctttgccatt ttaccagatg gagaagttgt tggagactct     1260

gaaaaatttg agattgaaaa ctgtctagcc aacaaggtgg atttgagctt cagcccagca     1320

caaagtcccc cagcctcaca tgcccacctg caagtagcag ctgctccgca gtccctctgt     1380

gcccttcgtg ctgtggacca aagtgtgctg ctcatgaagc ctgaggctga gctctctgtg     1440

tcctcagtat ataatctgct aactgtgaag gatctcacca attttcctga caatgtggac     1500

cagcaggagg aagaacaagg acactgtccc cgtcctttct tcattcataa tggagccatc     1560

tatgttccct tatcaagtaa tgaagcagat atttatagct tcctcaaggg gatgggattg     1620

aaggtgttca ctaactcaaa aatccgaaaa ccaaagtcgt gttcagtcat cccttccgtg     1680

tctgcaggag cagtaggtca aggatactat ggagcaggtc taggagtagt agagagacca     1740

tatgttcctc aattaggcac atataatgtg atacccttaa ataatgaaca aagttcaggg     1800

ccagtccctg aaacggtgcg aagctatttt cctgagactt ggatctggga gttggtggca     1860

gtgaactcat caggtgtggc tgaggtagga gtaacagtcc ctgacaccat caccgagtgg     1920

aaggcagggg ccttctgcct gtctgaagat gctggacttg gtatctcttc cactgcctct     1980

ctccgagcct tccagccctt ctttgtggag ctcacaatgc cttactctgt gattcgtgga     2040

gaggtcttca cactcaaggc cacggtccta aactaccttc ccaaatgcat ccgggctgaa     2100

ggtattgagc aagaaaagac tttcagttcc atgacctgtg cctcaggtgc taatgtgtct     2160

gagcagttgt ccttgaagct cccatcaaat gtggtcaaag aatctgccag agcttctttc     2220

tcagttctgg gtgacatatt aggttctgct atgcaaaata tacaaaatct cctccagatg     2280

ccatatggct gtggagaaca gaacatggtc ctatttgctc ctaacatcta tgtcttgaac     2340

tatctgaatg aaacccagca gctgacgcag gagatcaagg ccaaggccgt tggctatctc     2400

atcactggtt accagagaca gctgaactac aaacaccaag atggctccta cagcaccttt     2460

ggggaacgat atggcaggaa ccagggcaac acttggctca cagcttttgt actgaagact     2520

ttcgcccagg ctcgatccta catcttcatt gatgaagcac acattaccca atctctcacg     2580

tggctctccc agatgcagaa ggacaatggc tgtttcagga gctctgggtc actgctcaac     2640

aatgccataa agggaggtgt agaagatgaa gcgaccctct ccgcctatgt tactattgcc     2700

cttctggaaa ttcctctccc agtcactaac cctattgttc gcaatgccct gttctgcctg     2760

gagtcagcct ggaatgtagc aaaggagggg acccatggga gccatgtcta caccaaggca     2820

ttgctggcct atgctttttc cctactggga aagcaaaatc agaatagaga aatactgaac     2880

tcacttgata aggaagctgt gaaagaagac aacctcgtcc attgggagcg ccctcagaga     2940

cccaaggcac cagtggggca tctttaccaa ccccaggctc cctctgctga ggtggagatg     3000

acatcctatg tgctcctcgc ttatctcacg gcccagccag cccccacctc aggggacctg     3060

acctctgcaa ctaacattgt gaagtggatc atgaagcagc agaacgccca aggtggtttc     3120

tcctccaccc aggacacagt ggtggctctc catgccctgt ccaggtatgg agcagccact     3180

ttcaccagaa ctgagaaaac tgcacaggtc accgttcagg attcacagac cttttctaca     3240

aatttccaag tagacaacaa caacctccta ttactgcagc agatctcatt gccagagctc     3300

cctggagaat atgtcataac agtaactggg gaaagatgtg tgtatcttca gacatccatg     3360

aaatacaata ttcttccaga gaaagaggac tccccatttg ctttaaaagt gcagactgtg     3420

ccccagactt gcgatggaca caaagcccac accagctttc agatctcact gaccatcagt     3480

tacacaggaa accgtcctgc ttccaatatg gtgattgttg atgtaaagat ggtatctggt     3540

tttattcccc tgaaaccaac agtaaaaatg cttgaaagat ctagctctgt gagccggaca     3600

gaagtgagca acaaccatgt cctcatttat gtggaacagg tgacaaatca gacgctaagt     3660

ttttccttca tggttctgca agacatccca gtaggagact tgaagccagc aattgttaaa     3720

gtctatgatt actatgagac agatgagtct gtggttgctg agtatatcgc cccctgcagc     3780

acagatacag agcatggaaa tgtt                                            3804


<210>  4234
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  4234
caagaggccc agacagagtt gccccaggcc cggatcagct gcccagaagg caccaatgcc       60

tatcgctcct actgctacta ctttaatgaa gaccgtgaga cctgggttga tgcagatctc      120

tattgccaga acatgaattc gggcaacctg gtgtctgtgc tcacccaggc cgagggtgcc      180

tttgtggcct cactgattaa ggagagtggc actgatgact tcaatgtctg gattggcctc      240

catgacccca aaaagaaccg ccgctggcac tggagcagtg ggtccctggt ctcctacaag      300

tcctggggca ttggagcccc aagcagtgtt aatcctggct actgtgtgag cctgacctca      360

agcacaggat tccagaaatg gaaggatgtg ccttgtgaag acaagttctc ctttgtctgc      420

aagttcaaaa ac                                                          432


<210>  4235
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  4235
caggagtccc agacagagct gcctaatccc cgaatcagct gcccagaagg caccaatgcc       60

tatcgctcct actgctacta ctttaatgaa gaccctgaga cctgggttga tgcagatctc      120

tattgccaga acatgaattc aggcaacctg gtgtctgtgc tcacccaggc ggagggtgcc      180

ttcgtggcct cactgattaa ggagagtagc actgatgaca gcaatgtctg gattggcctc      240

catgacccaa aaaagaaccg ccgctggcac tggagtagtg ggtccctggt ctcctacaag      300

tcctgggaca ctggatcccc gagcagtgct aatgctggct actgtgcaag cctgacttca      360

tgctcaggat tcaagaaatg gaaggatgaa tcttgtgaga agaagttctc ctttgtttgc      420

aagttcaaaa ac                                                          432


<210>  4236
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  4236
atcagctgtc ccaaaggctc caaggcctat ggctccccct gctatgcctt gtttttgtca       60

ccaaaatcct ggatggatgc agatctggct tgccagaagc ggccctctgg aaaactggtg      120

tctgtgctca gtggggctga gggatccttc gtgtcctccc tggtgaggag cattagtaac      180

agctactcat acatctggat tgggctccat gaccccacac agggctctga gcctgatgga      240

gatggatggg agtggagtag cactgatgtg atgaattact ttgcatggga gaaaaatccc      300

tccaccatct taaaccctgg ccactgtggg agcctgtcaa gaagcacagg atttctgaag      360

tggaaagatt ataactgtga tgcaaagtta ccctatgtct gcaagttcaa ggac            414


<210>  4237
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  4237
gatatcatca tgagacccag ctgtgctcct ggatggtttt accacaagtc caattgctat       60

ggttacttca ggaagctgag gaactggtct gatgccgagc tcgagtgtca gtcttacgga      120

aacggagccc acctggcatc tatcctgagt ttaaaggaag ccagcaccat agcagagtac      180

ataagtggct atcagagaag ccagccgata tggattggcc tgcacgaccc acagaagagg      240

cagcagtggc agtggattga tggggccatg tatctgtaca gatcctggtc tggcaagtcc      300

atgggtggga acaagcactg tgctgagatg agctccaata acaacttttt aacttggagc      360

agcaacgaat gcaacaagcg ccaacacttc ctgtgcaagt accgacca                   408


<210>  4238
<211>  2154
<212>  DNA
<213>  Homo Sapiens

<400>  4238
tcgcgtcttc gccaggagga ctttcccccg cggattgtgg agcatccttc cgatgtcatc       60

gtctctaagg gcgagcccac gactctgaac tgcaaggcgg agggccggcc aacgcccacc      120

attgagtggt acaaagatgg ggagcgagtg gagactgaca aggacgatcc ccggtcccac      180

aggatgcttc tgcccagcgg atccttattc ttcttgcgca tcgtgcacgg gcgcaggagt      240

aaacctgatg aaggaagcta cgtttgtgtt gcgaggaact atcttggtga agcagtgagt      300

cgaaatgcgt ctctggaagt ggcattgtta cgagatgact tccgacaaaa ccccacagat      360

gttgtagtgg cagctggaga gcctgcaatc ctggagtgcc agcctccccg gggacaccca      420

gaacccacca tctactggaa aaaagacaaa gttcgaattg atgacaagga agaaagaata      480

agtatccgtg gtggaaaact gatgatctcc aataccagga aaagtgatgc agggatgtat      540

acttgtgttg gtaccaatat ggtgggagaa agggacagtg acccagcaga gctgactgtc      600

tttgaacgac ccacatttct caggaggcca attaaccagg tggtactgga ggaagaagct      660

gtagaatttc gttgtcaagt ccaaggagat cctcaaccaa ctgtgaggtg gaaaaaggat      720

gatgcagact tgccaagagg aaggtatgac atcaaagacg attacacact aagaattaaa      780

aagaccatga gtacagatga aggcacctat atgtgtattg ctgagaatcg ggttggaaaa      840

atggaagcct ctgctacact caccgtccga gctcgccctg ttgctccccc acagtttgtg      900

gttcggccaa gagatcagat tgttgctcaa ggtcgaacag tgacatttcc ctgtgaaact      960

aaaggaaacc cacagccagc tgttttttgg cagaaagaag gcagccagaa cctacttttc     1020

ccaaaccaac cccagcagcc caacagtaga tgctcagtgt caccaactgg agacctcaca     1080

atcaccaaca ttcaacgttc cgacgcgggt tactacatct gccaggcttt aactgtggca     1140

ggaagcattt tagcaaaagc tcaactggag gttactgatg ttttgacaga tagacctcca     1200

cctataattc tacaaggccc agccaaccaa acgctggcag tggatggtac agcgttactg     1260

aaatgtaaag ccactggtga tcctcttcct gtaattagct ggttaaagga gggatttact     1320

tttccgggta gagatccaag agcaacaatt caagagcaag gcacactgca gattaagaat     1380

ttacggattt ctgatactgg cacttatact tgtgtggcta caagttcaag tggagagact     1440

tcctggagtg cagtgctgga tgtgacagag tctggagcaa caatcagtaa aaactatgat     1500

ttaagtgacc tgccagggcc accatccaaa ccgcaggtca ctgatgttac taagaacagt     1560

gtcaccttgt cctggcagcc aggtacccct ggaacccttc cagcaagtgc atatatcatt     1620

gaggctttca gccaatcagt gagcaacagc tggcagaccg tggcaaacca tgtaaagacc     1680

accctctata ctgtaagagg actgcggccc aatacaatct acttattcat ggtcagagcg     1740

atcaaccccc aaggtctcag tgacccaagt cccatgtcag atcctgtgcg cacacaagat     1800

atcagcccac cagcacaagg agtggaccac aggcaagtgc agaaagagct aggagatgtc     1860

cttgtccgtc ttcataatcc agttgtgctg actcccacca cggttcaggt cacatggacg     1920

gttgatcgcc aaccccagtt tatccaaggc taccgagtga tgtatcgtca gacttcaggt     1980

ctgcaggcga catcttcgtg gcagaattta gatgccaaag tcccgactga acgaagtgct     2040

gtcttagtca acctgaaaaa gggggtgact tatgaaatta aagtacggcc atattttaat     2100

gagttccaag gaatggatag tgaatctaaa acggttcgta ctactgaaga agcc           2154


<210>  4239
<211>  1323
<212>  DNA
<213>  Homo Sapiens

<400>  4239
caggactccc cgccccagat cctagtccac ccccaggacc agctgttcca gggccctggc       60

cctgccagga tgagctgcca agcctcaggc cagccacctc ccaccatccg ctggttgctg      120

aatgggcagc ccctgagcat ggtgccccca gacccacacc acctcctgcc tgatgggacc      180

cttctgctgc tacagccccc tgcccgggga catgcccacg atggccaggc cctgtccaca      240

gacctgggtg tctacacatg tgaggccagc aaccggcttg gcacggcagt cagcagaggc      300

gctcggctgt ctgtggctgt cctccgggag gatttccaga tccagcctcg ggacatggtg      360

gctgtggtgg gtgagcagtt tactctggaa tgtgggccgc cctggggcca cccagagccc      420

acagtctcat ggtggaaaga tgggaaaccc ctggccctcc agcccggaag gcacacagtg      480

tccggggggt ccctgctgat ggcaagagca gagaagagtg acgaagggac ctacatgtgt      540

gtggccacca acagcgcagg acatagggag agccgcgcag cccgggtttc catccaggag      600

ccccaggact acacggagcc tgtggagctt ctggctgtgc gaattcagct ggaaaatgtg      660

acactgctga acccggatcc tgcagagggc cccaagccta gaccggcggt gtggctcagc      720

tggaaggtca gtggccctgc tgcgcctgcc caatcttaca cggccttgtt caggacccag      780

actgccccgg gaggccaggg agctccgtgg gcagaggagc tgctggccgg ctggcagagc      840

gcagagcttg gaggcctcca ctggggccaa gactacgagt tcaaagtgag accatcctct      900

ggccgggctc gaggccctga cagcaacgtg ctgctcctga ggctgccgga aaaagtgccc      960

agtgccccac ctcaggaagt gactctaaag cctggcaatg gcactgtctt tgtgagctgg     1020

gtcccaccac ctgctgaaaa ccacaatggc atcatccgtg gctaccaggt ctggagcctg     1080

ggcaacacat cactgccacc agccaactgg actgtagttg gtgagcagac ccagctggaa     1140

atcgccaccc atatgccagg ctcctactgc gtgcaagtgg ctgcagtcac tggtgctgga     1200

gctggggagc ccagtagacc tgtctgcctc cttttagagc aggccatgga gcgagccacc     1260

caagaaccca gtgagcatgg tccctggacc ctggagcagc tgagggctac cttgaagcgg     1320

cct                                                                   1323


<210>  4240
<211>  1092
<212>  DNA
<213>  Homo Sapiens

<400>  4240
caagaaacag agctgtcagt cagtgctgaa ttagtgccta cctcatcatg gaacatctca       60

agtgaactca acaaagattc ttacctgacc cttgatgaac caatgaataa catcaccacg      120

tctctgggcc agacagcaga actgcactgc aaagtctctg ggaatccacc tcccaccatc      180

cgctggttca aaaatgatgc tcctgtggtc caggagcccc ggaggctctc ctttcggtcc      240

accatctatg gctctcggct gcggattaga aacctcgaca ccacagacac aggctacttc      300

cagtgcgtgg caacaaacgg caaggaggtg gtttcttcca ctggagtctt gtttgtcaag      360

tttggccccc ctcccactgc aagtccagga tactcagatg agtatgaaga agatggattc      420

tgtcagccat acagagggat tgcatgtgca agatttattg gcaaccgcac cgtctatatg      480

gagtctttgc acatgcaagg ggaaatagaa aatcagatca cagctgcctt cactatgatt      540

ggcacttcca gtcacttatc tgataagtgt tctcagttcg ccattccttc cctgtgccac      600

tatgccttcc cgtactgcga tgaaacttca tccgtcccaa agccccgtga cttgtgtcgc      660

gatgaatgtg aaatcctgga gaatgtcctg tgtcaaacag agtacatttt tgcaagatca      720

aatcccatga ttctgatgag gctgaaactg ccaaactgtg aagatctccc ccagccagag      780

agcccagaag ctgcgaactg tatccggatt ggaattccca tggcagatcc tataaataaa      840

aatcacaagt gttataacag cacaggtgtg gactaccggg ggaccgtcag tgtgaccaaa      900

tcagggcgcc agtgccagcc atggaattcc cagtatcccc acacacacac tttcaccgcc      960

cttcgtttcc cagagctgaa tggaggccat tcctactgcc gcaacccagg gaatcaaaag     1020

gaagctccct ggtgcttcac cttggatgaa aactttaagt ctgatctgtg tgacatccca     1080

gcttgcggta aa                                                         1092


<210>  4241
<211>  1110
<212>  DNA
<213>  Homo Sapiens

<400>  4241
gaagtggagg ttctggatcc gaacgaccct ttaggacccc ttgatgggca ggacggcccg       60

attccaactc tgaaaggtta ctttctgaat tttctggagc cagtaaacaa tatcaccatt      120

gtccaaggcc agacggcaat tctgcactgc aaggtggcag gaaacccacc ccctaacgtg      180

cggtggctaa agaatgatgc cccggtggtg caggagccgc ggcggatcat catccggaag      240

acagaatatg gttcacgact gcgaatccag gacctggaca cgacagacac tggctactac      300

cagtgcgtgg ccaccaacgg gatgaagacc attaccgcca ctggcgtcct gtttgtgcgg      360

ctgggtccaa cgcacagccc aaatcataac tttcaggatg attaccacga ggatgggttc      420

tgccagcctt accggggaat tgcctgtgca cgcttcattg gcaaccggac catttatgtg      480

gactcgcttc agatgcaggg ggagattgaa aaccgaatca cagcggcctt caccatgatc      540

ggcacgtcta cgcacctgtc ggaccagtgc tcacagttcg ccatcccatc cttctgccac      600

ttcgtgtttc ctctgtgcga cgcgcgctcc cgggcaccca agccgcgtga gctgtgccgc      660

gacgagtgcg aggtgctgga gagcgacctg tgccgccagg agtacaccat cgcccgctcc      720

aacccgctca tcctcatgcg gcttcagctg cccaagtgtg aggcgctgcc catgcctgag      780

agccccgacg ctgccaactg catgcgcatt ggcatcccag ccgagaggct gggccgctac      840

catcagtgct ataacggctc aggcatggat tacagaggaa cggcaagcac caccaagtca      900

ggccaccagt gccagccgtg ggccctgcag cacccccaca gccaccacct gtccagcaca      960

gacttccctg agcttggagg ggggcacgcc tactgccgga accccggagg ccagatggag     1020

ggcccctggt gctttacgca gaataaaaac gtacgcatgg aactgtgtga cgtaccctcg     1080

tgtagtcccc gagacagcag caagatgggg                                      1110


<210>  4242
<211>  774
<212>  DNA
<213>  Homo Sapiens

<400>  4242
acagttttaa atagctgcct aaagtcgtgt gtaactaatc tgggccagca gcttgacctt       60

ggcacaccac ataatctgag tgaaccgtgt atccaaggat gtcacttttg gaactctgta      120

gatcagaaaa actgtgcttt aaagtgtcgg gagtcgtgtg aggttggctg tagcagcgcg      180

gaaggtgcat atgaagagga agtactggaa aatgcagacc taccaactgc tccctttgct      240

tcttccattg gaagccacaa tatgacatta cgatggaaat ctgcaaactt ctctggagta      300

aaatacatca ttcagtggaa atatgcacaa cttctgggaa gctggactta tactaagact      360

gtgtccagac cgtcctatgt ggtcaagccc ctgcacccct tcactgagta cattttccga      420

gtggtttgga tcttcacagc gcagctgcag ctctactccc ctccaagtcc cagttacagg      480

actcatcctc atggagttcc tgaaactgca cctttgatta ggaatattga gagctcaagt      540

cccgacactg tggaagtcag ctgggatcca cctcaattcc caggtggacc tattttgggt      600

tataacttaa ggctgatcag caaaaatcaa aaattagatg cagggacaca gagaaccagt      660

ttccagtttt actccacttt accaaatact atctacaggt tttctattgc agcagtaaat      720

gaagttggtg agggtccaga agcagaatct agtattacca cttcatcttc agca            774


<210>  4243
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  4243
tgcccaggtg cctgcgtatg ctacaatgag cccaaggtga cgacaagctg cccccagcag       60

ggcctgcagg ctgtgcccgt gggcatccct gctgccagcc agcgcatctt cctgcacggc      120

aaccgcatct cgcatgtgcc agctgccagc ttccgtgcct gccgcaacct caccatcctg      180

tggctgcact cgaatgtgct ggcccgaatt gatgcggctg ccttcactgg cctggccctc      240

ctggagcagc tggacctcag cgataatgca cagctccggt ctgtggaccc tgccacattc      300

cacggcctgg gccgcctaca cacgctgcac ctggaccgct gcggcctgca ggagctgggc      360

ccggggctgt tccgcggcct ggctgccctg cagtacctct acctgcagga caacgcgctg      420

caggcactgc ctgatgacac cttccgcgac ctgggcaacc tcacacacct cttcctgcac      480

ggcaaccgca tctccagcgt gcccgagcgc gccttccgtg ggctgcacag cctcgaccgt      540

ctcctactgc accagaaccg cgtggcccat gtgcacccgc atgccttccg tgaccttggc      600

cgcctcatga cactctatct gtttgccaac aatctatcag cgctgcccac tgaggccctg      660

gcccccctgc gtgccctgca gtacctgagg ctcaacgaca acccctgggt gtgtgactgc      720

cgggcacgcc cactctgggc ctggctgcag aagttccgcg gctcctcctc cgaggtgccc      780

tgcagcctcc cgcaacgcct ggctggccgt gacctcaaac gcctagctgc caatgacctg      840

cagggctgcg ctgtggccac cggcccttac catcccatct ggaccggcag ggccaccgat      900

gaggagccgc tggggcttcc caagtgctgc cagccagatg ccgctgacaa ggcctcagta      960

ctggagcctg gaagaccagc ttcggcaggc aatgcgctga agggacgcgt gccgcccggt     1020

gacagcccgc cgggcaacgg ctctggccca cggcacatca atgactcacc ctttgggact     1080

ctgcctggct ctgctgagcc cccgctcact gcagtgcggc ccgagggctc cgagccacca     1140

gggttcccca cctcgggccc tcgccggagg ccaggctgtt cacgcaagaa ccgcacccgc     1200

agccactgcc gtctgggcca ggcaggcagc gggggtggcg ggactggtga ctcagaaggc     1260

tca                                                                   1263


<210>  4244
<211>  1188
<212>  DNA
<213>  Homo Sapiens

<400>  4244
tgcccacggg actgtgtgtg ctacccggcg cccatgacgg tcagctgcca ggcgcacaac       60

tttgcagcca tcccggaggg catccccgtg gacagcgagc gcgtcttcct gcagaacaac      120

cgcatcggcc tcctccagcc cggccacttc agccccgcca tggtcaccct gtggatctac      180

tcgaacaaca tcacctacat ccaccccagc accttcgagg gcttcgtgca cctggaggag      240

ctggacctcg gcgacaaccg gcagctgcgg acgctggcac ccgagacctt ccagggcctg      300

gtgaagcttc acgccctcta cctctacaag tgtgggctca gcgccttgcc ggccggcgtc      360

tttggcggcc tgcacagcct gcagtacctc tacctgcagg acaaccacat cgagtacctc      420

caggacgaca tcttcgtgga cctggtcaac ctcagccacc tgtttctcca cggcaacaag      480

ctgtggagtc tgggcccggg caccttccgg ggcctggtga acctggaccg tcttttgctg      540

cacgagaacc agctgcagtg ggtccaccac aaggcattcc acgacctccg caggctgacc      600

accctcttcc tcttcaacaa cagcctctcg gagctgcagg gtgagtgcct ggccccgctg      660

ggggccctgg agttcctccg cctcaatggc aacccctggg actgtggttg tcgcgcgcgc      720

tccctgtggg aatggctgca gaggttccgg ggctccagct ccgctgtccc ctgtgtgtcc      780

cctgggctgc ggcacggcca ggacctgaag ctgctgaggg ccgaggactt ccggaactgc      840

acgggaccag cgtccccgca ccagatcaag tcacacacgc tcaccaccac cgacagggcc      900

gcccgcaagg aacaccactc accccacggc cccaccagga gcaagggcca cccgcacggc      960

ccccggcccg gccacaggaa gccggggaag aactgcacca accccaggaa ccgcaatcag     1020

atctctaagg cgggcgccgg gaaacaggcc cccgagctgc cagactatgc cccagactac     1080

cagcacaagt tcagttttga catcatgcct acggcccggc ccaagaggaa gggcaagtgt     1140

gcccgcagga cccccatccg tgcccccagc ggggtgcagc aggcctcc                  1188


<210>  4245
<211>  1032
<212>  DNA
<213>  Homo Sapiens

<400>  4245
caggccaaca acttctcctc tgtgccgctg tccctgccac ccagcactca gcgactcttc       60

ctgcagaaca acctcatccg cacgctgcgg ccaggcacct ttgggtccaa cctgctcacc      120

ctgtggctct tctccaacaa cctctccacc atctacccgg gcactttccg ccacttgcaa      180

gccctggagg agctggacct cggtgacaac cggcacctgc gctcgctgga gcccgacacc      240

ttccagggcc tggagcggct gcagtcgctg catttgtacc gctgccagct cagcagcctg      300

cccggcaaca tcttccgagg cctggtcagc ctgcagtacc tctacctcca ggagaacagc      360

ctgctccacc tacaggatga cttgttcgcg gacctggcca acctgagcca cctcttcctc      420

cacgggaacc gcctgcggct gctcacagag cacgtgtttc gcggcctggg cagcctggac      480

cggctgctgc tgcacgggaa ccggctgcag ggcgtgcacc gcgcggcctt ccgcggcctc      540

agccgcctca ccatcctcta cctgttcaac aacagcctgg cctcgctgcc cggcgaggcg      600

ctcgccgacc tgccctcgct cgagttcctg cggctcaacg ctaacccctg ggcgtgcgac      660

tgccgcgcgc ggccgctctg ggcctggttc cagcgcgcgc gcgtgtccag ctccgacgtg      720

acctgcgcca cccccccgga gcgccagggc cgagacctgc gcgcgctccg cgaggccgac      780

ttccaggcgt gtccgcccgc ggcacccacg cggccgggca gccgcgcccg cggcaacagc      840

tcctccaacc acctgtacgg ggtggccgag gccggggcgc ccccagccga tccctccacc      900

ctctaccgag atctgcctgc cgaagactcg cgggggcgcc agggcgggga cgcgcctact      960

gaggacgact actggggggg ctacgggggt gaggaccagc gaggggagca gatgtgcccc     1020

ggcgctgcct gc                                                         1032


<210>  4246
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  4246
atgacatctg gttctgtctt cttctacatc ttaatttttg gaaaatattt ttctcatggg       60

ggtggacagg atgtcaagtg ctcccttggc tatttcccct gtgggaacat cacaaagtgc      120

ttgcctcagc tcctgcactg taacggtgtg gacgactgcg ggaatcaggc cgatgaggac      180

aactgtggag acaacaatgg atggtctctg caatttgaca aatattttgc cagttactac      240

aaaatgactt cccaatatcc ttttgaggca gaaacacctg aatgtttggt cggttctgtg      300

ccagtgcaat gtctttgcca aggtctggag cttgactgtg atgaaaccaa tttacgagct      360

gttccatcgg tttcttcaaa tgtgactgca atgtcacttc agtggaactt aataagaaag      420

cttcctcctg attgcttcaa gaattatcat gatcttcaga agctgtacct gcaaaacaat      480

aagattacat ccatctccat ctatgctttc agaggactga atagccttac taaactgtat      540

ctcagtcata acagaataac cttcctgaag ccgggtgttt ttgaagatct tcacagacta      600

gaatggctga taattgaaga taatcacctc agtcgaattt ccccaccaac attttatgga      660

ctaaattctc ttattctctt agtcctgatg aataacgtcc tcacccgttt acctgataaa      720

cctctctgtc aacacatgcc aagactacat tggctggacc ttgaaggcaa ccatatccat      780

aatttaagaa atttgacttt tatttcctgc agtaatttaa ctgttttagt gatgaggaaa      840

aacaaaatta atcacttaaa tgaaaatact tttgcacctc tccagaaact ggatgaattg      900

gatttaggaa gtaataagat tgaaaatctt ccaccgctta tattcaagga cctgaaggag      960

ctgtcacaat tgaatctttc ctataatcca atccagaaaa ttcaagcaaa ccaatttgat     1020

tatcttgtca aactcaagtc tctcagccta gaagggattg aaatttcaaa tatccaacaa     1080

aggatgttta gacctcttat gaatctctct cacatatatt ttaagaaatt ccagtactgt     1140

gggtatgcac cacatgttcg cagctgtaaa ccaaacactg atggaatttc atctctagag     1200

aatctcttgg caagcattat tcagaga                                         1227


<210>  4247
<211>  1167
<212>  DNA
<213>  Homo Sapiens

<400>  4247
agaaaagtgg actctctctc cgaagacatc tccttgaccc agtctattta tgacaagaag       60

cttgtgttaa tgcagaaaaa tctccagggc ctggatccga aagccctgaa caactgctct      120

ttctgccatg aagctgggca gctggggcca gagatccgaa aactgcagga ggagctggag      180

ggaattcaga agctgcttct ggcccaggag gtgcagctgg accagacctt acaggcccag      240

gaggtgctct ccaccaccag cagacaaatc tcccaggaga tgggcagttg ctccttctcc      300

atccaccagg ttaaccagtc tctggggctc ttcctggccc aggtgagagg ctggcaggcc      360

accacagctg gcctggacct ctctctgaag gacctcaccc aggagtgcta cgatgtcaag      420

gctgcagtgc accagatcaa cttcaccgtg gggcagactt ccgagtggat ccacgggatc      480

cagcggaaga cagacgagga gaccctgacc ctccagaaga ttgtcaccga ctggcagaac      540

tacacacggc tcttcagcgg cctgcgcacc acctccacca agactggaga ggcggtcaag      600

aacatccagg ccaccctggg ggcctcctca cagcgcatca gccagaactc agagagcatg      660

cacgacctgg tactccaggt catgggcttg cagctgcagc tggataacat ctcgtccttc      720

ctggatgacc acgaagagaa catgcatgat cttcagtacc atacccacta cgcccagaac      780

cgcactgtgg agaggtttga gtctctggaa ggacgcatgg cttctcacga gattgaaatt      840

ggcaccatct tcaccaacat caatgccacc gacaaccacg tgcacagcat gctcaagtac      900

ctggatgacg tgcggctctc ctgcacgctg ggcttccaca cccatgccga ggagctctac      960

tacctgaaca agtctgtctc catcatgctg ggcaccacag acctgctccg ggagcgcttc     1020

agcctgctca gtgcccggct ggacctcaac gtccggaacc tctccatgat cgtggaggag     1080

atgaaggcag tggacacaca gcatggagaa atccttcgca atgtcaccat cctacgaggt     1140

cacactttgt tttcacataa tcggata                                         1167


<210>  4248
<211>  1206
<212>  DNA
<213>  Homo Sapiens

<400>  4248
tccgagctgg accccaaagg gcagcacgtc tgtgtggcca gcagcccctc tgctgagctg       60

cagtgctgcg caggctggag gcagaaggat caagaatgca ccatccccat ctgtgagggg      120

ccggacgcct gccagaaaga cgaggtgtgt gtgaagccgg gcctctgtcg atgcaagcct      180

ggattctttg gggcccactg cagctcccgc tgcccgggcc agtactgggg ccccgactgc      240

cgtgagagct gcccctgcca cccgcacggc cagtgcgagc cagccacggg cgcgtgccag      300

tgccaggccg accgctgggg agcccgctgc gagttcccgt gcgcctgcgg cccccacggg      360

cgctgcgacc ccgcgaccgg cgtgtgccac tgcgaacccg gctggtggtc gtccacgtgc      420

cgccgcccgt gccagtgcaa caccgcggcg gcgcgctgcg agcaggccac gggcgcctgc      480

gtgtgcaagc cgggctggtg ggggcgccgc tgcagcttcc gctgcaactg ccacggctcc      540

ccgtgcgagc aggactccgg ccgctgcgcc tgccggccgg gctggtgggg tcccgaatgc      600

cagcagcagt gcgagtgtgt gcggggccgc tgcagcgccg cctccggcga gtgcacctgc      660

ccgcccggct tccgcggagc gcgctgcgag ctgccctgcc cggcaggcag ccacggggtg      720

cagtgcgcac acagctgtgg ccgctgcaaa cacaatgagc cgtgctctcc agacacaggc      780

agctgtgagt cctgcgagcc gggctggaac gggacccagt gccagcagcc ctgcctgcct      840

ggcacctttg gcgagagctg cgaacagcag tgccctcact gccgacatgg ggaggcctgt      900

gagccagata ctggccactg tcagcgctgt gaccctggct ggctggggcc caggtgtgaa      960

gacccctgcc ccactggtac ctttggggaa gactgtggct ctacctgccc cacctgtgtt     1020

caggggtcct gtgatactgt gacaggggac tgtgtctgca gtgccggcta ctgggggccc     1080

agctgcaacg cctcctgccc agccggtttc catggaaaca actgctcagt tccttgtgaa     1140

tgcccagagg gactctgcca ccctgtctct gggtcctgcc agccaggctc tggcagtcgg     1200

gacact                                                                1206


<210>  4249
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  4249
caggagctaa accctagagg gaggaatgtg tgtcgtgccc ccggttcaca ggtccctaca       60

tgttgcgctg gttggaggca acaaggtgat gaatgcggga tagccgtttg cgaaggcaac      120

agcacctgca gcgagaatga agtatgtgtc aggcctggag aatgcagatg caggcatggg      180

tacttcggag cgaactgcga tactaaatgt cctagacagt tctggggacc agattgtaaa      240

gaactttgca gctgccaccc tcacgggcaa tgtgaggatg tgacgggtca atgcacttgt      300

catgcaagga ggtggggtgc caggtgcgaa cacgcctgtc agtgccaaca tggcacatgc      360

catcctagga gtggcgcctg tcgttgcgaa cctggatggt ggggagcgca atgtgcgtcc      420

gcttgctatt gctccgccac atccagatgc gatccccaaa caggggcgtg cctgtgccat      480

gcggggtggt gggggaggag ttgtaataac caatgcgcct gcaacagttc accgtgtgag      540

caacagagtg gtagatgcca atgccgtgaa agaacattcg gcgcaaggtg cgaccgttat      600

tgccagtgct ttcgtggtcg ttgtcaccca gtagatggga cgtgcgcttg tgagcctggt      660

tatagaggaa agtactgcag agagccttgt ccggccgggt tctacggact tggatgtcgt      720

cgtcgttgcg ggcagtgtaa ggggcagcaa ccttgtactg tggcggaggg cagatgcttg      780

acgtgtgaac ctggttggaa tgggacgaaa tgtgaccaac cttgtgccac tggcttttac      840

ggtgaaggtt gttctcacag gtgtccacca tgccgtgacg gacacgcctg caaccacgtt      900

acgggcaaat gtacgaggtg taacgcagga tggatcggtg accgttgtga gacgaaatgc      960

tcaaatggga cctacggcga agactgtgcc ttcgtatgcg cggactgtgg aagtggacac     1020

tgcgacttcc agtccgggag gtgcctatgc agccccggtg ttcacggccc gcattgcaat     1080

gttacatgtc cccctggtct gcatggtgca gactgtgccc aggcgtgctc ctgtcatgag     1140

gatacctgtg acccggttac aggggcttgt cacttggaaa ctaatcaaag gaag           1194


<210>  4250
<211>  426
<212>  DNA
<213>  Homo Sapiens

<400>  4250
gggggctgcg tggaggtgga ctcggagacc gaggccgtgt atgggatgac cttcaaaatt       60

ctttgcatct cctgcaagcg ccgcagcgag accaacgctg agaccttcac cgagtggacc      120

ttccgccaga agggcactga ggagtttgtc aagatcctgc gctatgagaa tgaggtgttg      180

cagctggagg aggatgagcg cttcgagggc cgcgtggtgt ggaatggcag ccggggcacc      240

aaagacctgc aggatctgtc tatcttcatc accaatgtca cctacaacca ctcgggcgac      300

tacgagtgcc acgtctaccg cctgctcttc ttcgaaaact acgagcacaa caccagcgtc      360

gtcaagaaga tccacattga ggtagtggac aaagccaaca gagacatggc atccatcgtg      420

tctgag                                                                 426


<210>  4251
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  4251
atggaggtca cagtacctgc caccctcaac gtcctcaatg gctctgacgc ccgcctgccc       60

tgcaccttca actcctgcta cacagtgaac cacaaacagt tctccctgaa ctggacttac      120

caggagtgca acaactgctc tgaggagatg ttcctccagt tccgcatgaa gatcattaac      180

ctgaagctgg agcggtttca agaccgcgtg gagttctcag ggaaccccag caagtacgat      240

gtgtcggtga tgctgagaaa cgtgcagccg gaggatgagg ggatttacaa ctgctacatc      300

atgaaccccc ctgaccgcca ccgtggccat ggcaagatcc atctgcaggt cctcatggaa      360

gagccccctg agcgggactc cacggtggcc                                       390


<210>  4252
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  4252
ttccctgtgt gtgtggaagt gccctcggag acggaggccg tgcagggcaa ccccatgaag       60

ctgcgctgca tctcctgcat gaagagagag gaggtggagg ccaccacggt ggtggaatgg      120

ttctacaggc ccgagggcgg taaagatttc cttatttacg agtatcggaa tggccaccag      180

gaggtggaga gcccctttca ggggcgcctg cagtggaatg gcagcaagga cctgcaggac      240

gtgtccatca ctgtgctcaa cgtcactctg aacgactctg gcctctacac ctgcaatgtg      300

tcccgggagt ttgagtttga ggcgcatcgg ccctttgtga agacgacgcg gctgatcccc      360

ctaagagtca ccgaggaggc tggagaggac ttcacctctg tggtctcaga a               411


<210>  4253
<211>  396
<212>  DNA
<213>  Homo Sapiens

<400>  4253
ttggaagttt cagtgggtaa ggccaccgat atatacgccg tgaacggcac ggaaatcttg       60

ctaccttgca ccttctcatc ttgcttcgga ttcgaagatt tgcattttag atggacttac      120

aacagttcag atgctttcaa gatacttatt gaaggaacgg tcaaaaacga gaaaagtgac      180

ccgaaggtaa ctctaaaaga cgatgatagg ataacgttag tcggaagcac taaggaaaag      240

atgaacaata taagcatagt ccttcgtgac ctggagtttt ccgacacggg taaatacacc      300

tgccatgtta aaaaccccaa agagaataat ctacagcatc acgctactat ctttctacag      360

gttgttgaca ggctagagga ggtagacaat acggtt                                396


<210>  4254
<211>  2895
<212>  DNA
<213>  Homo Sapiens

<400>  4254
gggggcagcg ggctcccagg gtcagtcgac gtggatgagt gctcagaggg cacagatgac       60

tgccacatcg atgccatctg tcagaacacg cccaagtcct acaaatgcct ctgcaagcca      120

ggctacaagg gggaaggcaa gcagtgtgaa gacattgacg agtgtgagaa tgactactac      180

aatgggggct gtgtccacga gtgcatcaac atcccgggga actacaggtg tacctgcttt      240

gatggcttca tgctggcaca cgatggacac aactgcctgg atgtggacga gtgtcaggac      300

aataatggtg gctgccagca gatctgcgtc aatgccatgg gcagctacga gtgtcagtgc      360

cacagtggct tcttccttag tgacaaccag catacctgca tccaccgctc caatgagggt      420

atgaactgca tgaacaaaga ccatggctgt gcccacatct gccgggagac gcccaaaggt      480

ggggtggcct gcgactgcag gcccggcttt gaccttgccc aaaaccagaa ggactgcaca      540

ctaacctgta attatggaaa cggaggctgc cagcacagct gtgaggacac agacacaggc      600

cccacgtgtg gttgccacca gaagtacgcc ctccactcag acggtcgcac gtgcatcgag      660

acgtgcgcag tcaataacgg aggctgcgac cggacatgca aggacacagc cactggcgtg      720

cgatgcagct gccccgttgg attcacactg cagccggacg ggaagacatg caaagacatc      780

aacgagtgcc tggtcaacaa cggaggctgc gaccacttct gccgcaacac cgtgggcagc      840

ttcgagtgcg gctgccggaa gggctacaag ctgctcaccg acgagcgcac ctgccaggac      900

atcgacgagt gctccttcga gcggacctgt gaccacatct gcatcaactc cccgggcagc      960

ttccagtgcc tgtgtcaccg cggctacatc ctctacggga caacccactg cggagatgtg     1020

gacgagtgca gcatgagcaa cgggagctgt gaccagggct gcgtcaacac caagggcagc     1080

tacgagtgcg tctgtccccc ggggaggcgg ctccactgga acgggaagga ttgcgtggag     1140

acaggcaagt gtctttctcg cgccaagacc tccccccggg cccagctgtc ctgcagcaag     1200

gcaggcggtg tggagagctg cttcctttcc tgcccggctc acacactctt cgtgccagac     1260

tcggaaaata gctacgtcct gagctgcgga gttccagggc cgcagggcaa ggcgctgcag     1320

aaacgcaacg gcaccagctc tggcctcggg cccagctgct cagatgcccc caccaccccc     1380

atcaaacaga aggcccgctt caagatccga gatgccaagt gccacctccg gccccacagc     1440

caggcacgag caaaggagac cgccaggcag ccgctgctgg accactgcca tgtgactttc     1500

gtgaccctca agtgtgactc ctccaagaag aggcgccgtg gccgcaagtc cccatccaag     1560

gaggtgtccc acatcacagc agagtttgag atcgagacaa agatggaaga ggcctcagac     1620

acatgcgaag cggactgctt gcggaagcga gcagaacaga gcctgcaggc cgccatcaag     1680

accctgcgca agtccatcgg ccggcagcag ttctatgtcc aggtctcagg cactgagtac     1740

gaggtagccc agaggccagc caaggcgctg gaggggcagg gggcatgtgg cgcaggccag     1800

gtgctacagg acagcaaatg cgttgcctgt gggcctggca cccacttcgg tggtgagctc     1860

ggccagtgtg tgtcatgtat gccaggaaca taccaggaca tggaaggcca gctcagttgc     1920

acaccgtgcc ccagcagcga cgggcttggt ctgcctggtg cccgcaacgt gtcggaatgt     1980

ggaggccagt gttctccagg cttcttctcg gccgatggct tcaagccctg ccaggcctgc     2040

cccgtgggca cgtaccagcc tgagcccggg cgcaccggct gcttcccctg tggagggggt     2100

ttgctcacca aacacgaagg caccacctcc ttccaggact gcgaggctaa agtgcactgc     2160

tcccccggcc accactacaa caccaccacc caccgctgca tccgctgccc cgtcggcacc     2220

taccagcccg agtttggcca gaaccactgc atcacctgtc cgggcaacac cagcacagac     2280

ttcgatggct ccaccaacgt cacacactgc aaaaaccagc actgcggcgg cgagcttggt     2340

gactacaccg gctacatcga gtcccccaac taccctggcg actacccagc caacgctgaa     2400

tgcgtctggc acatcgcgcc tcccccaaag cgcaggatcc tcatcgtggt ccctgagatc     2460

ttcctgccca tcgaggatga gtgcggcgat gttctggtca tgaggaagag tgcctctccc     2520

acgtccatca ccacctatga gacctgccag acctacgaga ggcccatcgc cttcacctcc     2580

cgctcccgca agctctggat ccagttcaaa tccaatgaag gcaacagcgg caaaggcttc     2640

caagtgccct atgtcaccta cgatgaggac taccagcaac tcatagagga catcgtgcgc     2700

gatgggcgcc tgtacgcctc ggagaaccac caggaaattt tgaaagacaa gaagctgatc     2760

aaggccctct tcgacgtgct ggcgcatccc cagaactact tcaagtacac agcccaggaa     2820

tccaaggaga tgttcccacg gtccttcatc aaactgctgc gctccaaagt gtctcggttc     2880

ctgcggccct acaaa                                                      2895


<210>  4255
<211>  2328
<212>  DNA
<213>  Homo Sapiens

<400>  4255
gtcccgccgg gtcggggccg tgccgcgggg ccgcaggagg atgtagatga gtgtgcccaa       60

gggctagatg actgccatgc cgacgccctg tgtcagaaca cacccacctc ctacaagtgc      120

tcctgcaagc ctggctacca aggggaaggc aggcagtgtg aggacatcga tgaatgtgga      180

aatgagctca atggaggctg tgtccatgac tgtttgaata ttccaggcaa ttatcgttgc      240

acttgttttg atggcttcat gttggctcat gacggtcata attgtcttga tgtggacgag      300

tgcctggaga acaatggcgg ctgccagcat acctgtgtca acgtcatggg gagctatgag      360

tgctgctgca aggaggggtt tttcctgagt gacaatcagc acacctgcat tcaccgctcg      420

gaagagggcc tgagctgcat gaataaggat cacggctgta gtcacatctg caaggaggcc      480

ccaaggggca gcgtcgcctg tgagtgcagg cctggttttg agctggccaa gaaccagaga      540

gattgcatct tgacctgtaa ccatgggaac ggtgggtgcc agcactcctg tgacgataca      600

gccgatggcc cagagtgcag ctgccatcca cagtacaaga tgcacacaga tgggaggagc      660

tgccttgagc gagaggacac tgtcctggag gtgacagaga gcaacaccac atcagtggtg      720

gatggggata aacgggtgaa acggcggctg ctcatggaaa cgtgtgctgt caacaatgga      780

ggctgtgacc gcacctgtaa ggatacttcg acaggtgtcc actgcagttg tcctgttgga      840

ttcactctcc agttggatgg gaagacatgt aaagatattg atgagtgcca gacccgcaat      900

ggaggttgtg atcatttctg caaaaacatc gtgggcagtt ttgactgcgg ctgcaagaaa      960

ggatttaaat tattaacaga tgagaagtct tgccaagatg tggatgagtg ctctttggat     1020

aggacctgtg accacagctg catcaaccac cctggcacat ttgcttgtgc ttgcaaccga     1080

gggtacaccc tgtatggctt cacccactgt ggagacacca atgagtgcag catcaacaac     1140

ggaggctgtc agcaggtctg tgtgaacaca gtgggcagct atgaatgcca gtgccaccct     1200

gggtacaagc tccactggaa taaaaaagac tgtgtggctt cttgtgacct gagctgcatc     1260

gtaaagcgaa ccgagaagcg gctccgtaaa gccatccgca cgctcagaaa ggccgtccac     1320

agggagcagt ttcacctcca gctctcaggc atgaacctcg acgtggctaa aaagcctccc     1380

agaacatctg aacgccaggc agagtcctgt ggagtgggcc agggtcatgc agaaaaccaa     1440

tgtgtcagtt gcagggctgg gacctattat gatggagcac gagaacgctg cattttatgt     1500

ccaaatggaa ccttccaaaa tgaggaagga caaatgactt gtgaaccatg cccaagacca     1560

ggaaattctg gggccctgaa gaccccagaa gcttggaata tgtctgaatg tggaggtctg     1620

tgtcaacctg gtgaatattc tgcagatggc tttgcacctt gccagctctg tgccctgggc     1680

acgttccagc ctgaagctgg tcgaacttcc tgcttcccct gtggaggagg ccttgccacc     1740

aaacatcagg gagctacttc ctttcaggac tgtgaaacca gagttcaatg ttcacctgga     1800

catttctaca acaccaccac tcaccgatgt attcgttgcc cagtgggaac ataccagcct     1860

gaatttggaa aaaataattg tgtttcttgc ccaggaaata ctacgactga ctttgatggc     1920

tccacaaaca taacccagtg taaaacttca tccaattctg tgacaacata tgaaacctgc     1980

cagacctacg aacgccccat cgccttcacc tccaggtcaa agaagctgtg gattcagttc     2040

aagtccaatg aagggaacag cgctagaggg ttccaggtcc catacgtgac atatgatgag     2100

gactaccagg aactcattga agacatagtt cgagatggca ggctctatgc atctgagaac     2160

catcaggaaa tacttaagga taagaaactt atcaaggctc tgtttgatgt cctggcccat     2220

ccccagaact atttcaagta cacagcccag gagtcccgag agatgtttcc aagatcgttc     2280

atccgattgc tacgttccaa agtgtccagg tttttgagac cttacaaa                  2328


<210>  4256
<211>  2916
<212>  DNA
<213>  Homo Sapiens

<400>  4256
gcccagtaca gcaaagccgc gcaagatgtg gatgagtgtg tggaggggac tgacaactgc       60

cacatcgatg ctatctgcca gaacaccccg aggtcataca agtgcatctg caagtctggc      120

tacacagggg acggcaaaca ctgcaaagac gtggatgagt gcgagcgaga ggataatgca      180

ggttgtgtgc atgactgtgt caacatccct ggcaattacc ggtgtacctg ctatgatgga      240

ttccacctgg cacatgacgg acacaactgt ctggatgtgg acgagtgtgc cgagggcaac      300

ggcggctgtc agcagagctg tgtcaacatg atgggcagct atgagtgcca ctgccgggaa      360

ggcttcttcc tcagcgacaa ccagcatacc tgtatccagc ggccagaagg aatgaactgc      420

atgaacaaga accacggctg tgcccacatt tgccgggaga cacccaaggg gggtattgcc      480

tgtgaatgcc gtcctggctt tgagcttacc aagaaccaac gggactgtaa attgacatgc      540

aactatggta acggcggctg ccagcacacg tgtgatgaca cagagcaggg tccccggtgc      600

ggctgccata tcaagtttgt gctccatacc gacgggaaga catgcatcga gacctgtgct      660

gtcaacaacg ggggctgtga cagtaagtgc catgatgcag cgattggtgt ccactgcacc      720

tgccctgtgg gcttcatgct gcagccagac aggaagacgt gcaaagatat agatgagtgc      780

cgcttaaaca acgggggctg tgaccatatt tgccgcaaca cagtgggcag cttcgaatgc      840

agttgcaaga aaggctataa gcttctcatc aatgagagga actgccagga tatagacgag      900

tgttcctttg atcgaacctg tgaccacata tgtgtcaaca caccaggaag cttccagtgt      960

ctctgccatc gtggctacct gttgtatggt atcacccact gtggggatgt ggatgaatgc     1020

agcatcaacc ggggaggttg ccgctttggc tgcatcaaca ctcctggcag ctaccagtgt     1080

acctgcccag caggccaggg tcggctgcac tggaatggca aagattgcac agagccactg     1140

aagtgtcagg gcagtcctgg ggcctcgaaa gccatgctca gctgcaaccg gtctggcaag     1200

aaggacacct gtgccctgac ctgtccctcc agggcccgat ttttgccaga gtctgagaat     1260

ggcttcacgg tgagctgtgg gacccccagc cccagggctg ctccagcccg agctggccac     1320

aatgggaaca gcaccaactc caaccactgc catgaggctg cagtgctgtc cattaaacaa     1380

cgggcctcct tcaagatcaa ggatgccaaa tgccgtttgc acctgcgaaa caaaggcaaa     1440

acagaggagg ctggcagaat cacagggcca ggtggtgccc cctgctctga atgccaggtc     1500

accttcatcc accttaagtg tgactcctct cggaagggca agggccgacg ggcccggacc     1560

cctccaggca aagaggtcac aaggctcacc ctggaactgg aggcagaggt cagagccgaa     1620

gaaaccacag ccagctgtgg gctgccctgc ctccgacagc gaatggaacg gcggctgaaa     1680

ggatccctga agatgctcag aaagtccatc aaccaggacc gcttcctgct gcgcctggca     1740

ggccttgatt atgagctggc ccacaagccg ggcctggtag ccggggagcg agcagagccg     1800

atggagtcct gtaggcccgg gcagcaccgt gctgggacca agtgtgtcag ctgcccgcag     1860

ggaacgtatt accacggcca gacggagcag tgtgtgccat gcccagcggg caccttccag     1920

gagagagaag ggcagctctc ctgcgacctt tgccctggga gtgatgccca cgggcctctt     1980

ggagccacca acgtcaccac gtgtgcaggt cagtgcccac ctggccaaca ctctgtagat     2040

gggttcaagc cctgtcagcc atgcccacgt ggcacctacc aacctgaagc aggacggacc     2100

ctatgcttcc cttgtggtgg gggcctcacc accaagcatg aaggggccat ttccttccaa     2160

gactgtgaca ccaaagtcca gtgctcccca gggcactact acaacaccag catccaccgc     2220

tgtattcgct gtgccatggg ctcctatcag cccgacttcc gtcagaactt ctgcagccgc     2280

tgtccaggaa acacaagcac agactttgat ggctctacca gtgtggccca atgcaagaat     2340

cgtcagtgtg gtggggagct gggtgagttc actggctata ttgagtcccc caactacccg     2400

ggcaactacc cagctggtgt ggagtgcatc tggaacatca accccccacc caagcgcaag     2460

atccttatcg tggtaccaga gatcttcctg ccatctgagg atgagtgtgg ggacgtcctc     2520

gtcatgagaa agaactcatc cccatcctcc attaccactt atgagacctg ccagacctac     2580

gagcgtccca ttgccttcac tgcccgttcc aggaagctct ggatcaactt caagacaagc     2640

gaggccaaca gcgcccgtgg cttccagatt ccctatgtta cctatgatga ggactatgag     2700

cagctggtag aagacattgt gcgagatggc cggctctatg cctctgaaaa ccaccaggag     2760

attttaaagg acaagaagct catcaaggcc ttctttgagg tgctagccca cccccagaac     2820

tacttcaagt acacagagaa acacaaggag atgctgccaa aatccttcat caagctgctc     2880

cgctccaaag tttccagctt cctgaggccc tacaaa                               2916


<210>  4257
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  4257
caaattgtgg ctactaattt gccccctgaa gatcaagatg gctctgggga tgactctgac       60

aacttctccg gctcaggtgc aggtgctttg caagatatca ccttgtcaca gcagaccccc      120

tccacttgga aggacacgca gctcctgacg gctattccca cgtctccaga acccaccggc      180

ctggaggcta cagctgcctc cacctccacc ctgccggctg gagaggggcc caaggaggga      240

gaggctgtag tcctgccaga agtggagcct ggcctcaccg cccgggagca ggaggccacc      300

ccccgaccca gggagaccac acagctcccg accactcatc aggcctcaac gaccacagcc      360

accacggccc aggagcccgc cacctcccac ccccacaggg acatgcagcc tggccaccat      420

gagacctcaa cccctgcagg acccagccaa gctgaccttc acactcccca cacagaggat      480

ggaggtcctt ctgccaccga gagggctgct gaggatggag cctccagtca gctcccagca      540

gcagagggct ctggggagca ggacttcacc tttgaaacct cgggggagaa tacggctgta      600

gtggccgtgg agcctgaccg ccggaaccag tccccagtgg atcagggggc cacgggggcc      660


<210>  4258
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  4258
gagtcgagag cagagctgac atctgataaa gacatgtacc ttgacaacag ctccattgaa       60

gaagcttcag gagtgtatcc tattgatgac gatgactacg cttctgcgtc tggctcggga      120

gctgatgagg atgtagagag tccagagctg acaacaactc gaccacttcc aaagatactg      180

ttgactagtg ctgctccaaa agtggaaacc acgacgctga atatacagaa caagatacct      240

gctcagacaa agtcacctga agaaactgat aaagagaaag ttcacctctc tgactcagaa      300

aggaaaatgg acccagccga agaggataca aatgtgtata ctgagaaaca ctcagacagt      360

ctgtttaaac ggacagaa                                                    378


<210>  4259
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  4259
gagtcgatcc gagagactga ggtcatcgac ccccaggacc tcctagaagg ccgatacttc       60

tccggagccc taccagacga tgaggatgta gtggggcccg ggcaggaatc tgatgacttt      120

gagctgtctg gctctggaga tctggatgac ttggaagact ccatgatcgg ccctgaagtt      180

gtccatccct tggtgcctct agataaccat atccctgaga gggcagggtc tgggagccaa      240

gtccccaccg aacccaagaa actagaggag aatgaggtta tccccaagag aatctcaccc      300

gttgaagaga gtgaggatgt gtccaacaag gtgtcaatgt ccagcactgt gcagggcagc      360

aacatctttg agagaacgga g                                                381


<210>  4260
<211>  4593
<212>  DNA
<213>  Homo Sapiens

<400>  4260
cctaacatca ccagaggccc cctggacagc acggtgatcg atggcatgtc agtggtgcta       60

gcatgtgaga cctcgggggc gccccgacca gctatcactt ggcagaaagg ggagcgcatc      120

ttggccagtg gctctgtgca gctgcctcgc ttcacacccc tggagtcggg cagcctcctc      180

atcagcccca cacacatctc cgatgcgggg acctacacct gcctggccac caactctcgg      240

ggggtcgatg aggcctcagc agacctagtc gtttgggctc ggacccgcat caccaagccc      300

ccccaggatc agagtgtcat caagggcacc caggcctcca tggtgtgcgg agtgacccac      360

gacccccgag taaccatcag gtacatctgg gagaaggacg gggccaccct gggcacggag      420

agccatcctc gtatccgcct ggacagaaac ggctccctgc acatctcaca gacgtggtcg      480

ggagacatcg gcacgtacac ctgccgggtg atctcagcag gaggcaacga ctctcgcagt      540

gcccacctgc gagtcaggca actgccccac gcgcccgagc acccagtggc cactctcagc      600

accgtggaaa ggcgagccat caacctgacg tggaccaagc cctttgatgg caacagcccc      660

ctgatccgct acattctgga gatgtcggag aacaatgccc cctggactgt actcctggcc      720

agtgtggacc ccaaagctac ctcagtgaca gtcaagggcc tggttcctgc acgctcctac      780

cagttccgtc tttgtgccgt caacgacgtg gggaaaggac agttcagcaa agacaccgag      840

agggtctccc tccccgagga gccccccacg gcccctccac agaacgtcat cgccagcggt      900

cgaaccaacc agtccatcat gatccagtgg cagccgcctc ctgagagcca ccagaatgga      960

attctcaagg gttacatcat caggtactgc ctggccgggc tgcccgtggg gtaccagttt     1020

aagaacatca cggatgctga tgtgaacaac ctgctgctgg aggatctcat catttggacc     1080

aactacgaga tcgaggtggc tgcttacaac agcgctgggc tgggggtcta cagcagtaaa     1140

gtcaccgagt ggacgctgca gggagttccc acagtccctc cgggcaatgt gcacgcggaa     1200

gccaccaatt ccacgaccat ccgcttcacc tggaacgccc ccagccccca gttcatcaac     1260

ggcatcaacc agggctacaa gctgatcgcc tgggagccgg aacaggaaga ggaggttacc     1320

atggtgaccg cccggcctaa ctttcaagac agcatccacg tgggcttcgt gtctggcctg     1380

aagaagttca ccgagtactt cacctcagtg ctgtgtttca ccacccccgg ggacgggcca     1440

cgcagcaccc cgcagctggt gcgcacccat gaggatgtgc ctgggcccgt gggacacctg     1500

agcttcagtg agatcctgga cacatcgctg aaggtcagct ggcaagagcc gggagagaaa     1560

aatggcatcc tcacagggta ccggatctcc tgggaggagt acaatcgaac caacacccgt     1620

gtgacccact acctgcccaa cgtgaccctg gagtaccgtg tcacgggcct caccgcgctc     1680

accacctaca ccatcgaggt ggccgccatg acctcaaagg gccagggcca agtgtccgcc     1740

tccaccatct cctctggggt gcccccagaa ctcccagggc cccccaccaa cctgggcatt     1800

tccaacatcg gcccccgctc tgtgaccttg cagttcaggc caggctacga tgggaaaacc     1860

tccatctccc gctggctggt ggaagcccag gtaggcgtgg ttggggaggg agaggagtgg     1920

ttgctgatcc accagctctc caatgagccc gatgcccgct ccatggaggt gcccgacctc     1980

aaccccttca cctgctacag cttccgcatg cgccaggtga acatcgtggg caccagcccc     2040

cccagtcagc cttctagaaa gatccagacc ctgcaggcac cccctgacat ggccccagcc     2100

aatgtgtctc tgcgcacagc cagtgagacc agcctgtggc tgcgctggat gcctctcccg     2160

gagatggaat acaatgggaa ccctgagtcc gtgggctata agatcaagta cagccggtca     2220

gacgggcatg gcaagacgct gagccacgtg gtgcaggacc gtgtggagcg ggactacacc     2280

atcgaggacc tggaggagtg gacagagtac cgcgtccagg tccaggcctt caacgccatc     2340

gggagcgggc cctggagcca gacggtggtg ggcaggaccc gggagtcagt tccctcttcc     2400

ggccccacca atgtgtctgc actggccacc acctccagca gcatgctggt gcgctggagc     2460

gaggtccccg aggctgatcg caacgggctc gtgctgggct ataaggtgat gtataaggag     2520

aaggactcgg acacccagcc ccgattctgg ctggtggaag gcaactcatc tcgcagtgcc     2580

cagctcaccg gcttgggcaa atacgtgctc tatgaagtcc aggtgctggc cttcacacgc     2640

atcggggacg gcagccccag ccaccctccc atcctggagc ggacgctgga tgatgtccca     2700

ggaccaccca tgggcatcct gttcccagag gtgcggacca cgtctgtgcg gctgatctgg     2760

cagccccctg ccgcccccaa tggcatcatt cttgcttacc agatcacaca ccggctcaac     2820

accaccacgg ccaacaccgc cactgtggag gtgctggcac ccagcgcccg gcagtacaca     2880

gccacgggcc tcaagccaga gtctgtctac ctgttccgca tcacggccca gacccgcaag     2940

ggctggggag aagctgccga ggccttggtg gtgaccaccg agaagagaga ccgtccgcag     3000

ccccccagca ggccaatggt gcagcaggag gatgtgagag cacgcagcgt gctgctgtcc     3060

tgggagccag ggagcgacgg gctctcccct gtgcgctact acaccatcca gacccgcgag     3120

ctgcccagcg gcaggtgggc actgcactcg gcctctgtga gccacaatgc ctccagcttc     3180

attgtggaca ggctgaagcc cttcacgtcc tacaagttcc gagtgaaggc gaccaatgac     3240

attggcgaca gcgagttcag cgaggagtcg gagtcactga ccaccctgca ggctgccccc     3300

gatgaagcac ccaccatcct ctccgtgacg ccccacacca ccacctccgt gctaatccga     3360

tggcagccgc cagcagagga caagatcaat ggcatcctcc tgggcttccg gatccgatac     3420

cgggagctgc tctatgaagg actgaggggc ttcatgcttc gaggcatcaa caacccaggg     3480

gccacatggg ctgagcttac ctccatgtac tccatgcgga acctgagccg gcccagcctc     3540

acgcagtacg agctggacaa cctgaacaag cacaggcggt acgagatacg gatgagcgtg     3600

tacaacgctg tgggtgaggg gccctccagc cccccgcagg aggtctttgt tggggaggca     3660

gtgcccacag cagcacctcg taacgtggtc gtccacggcg ccacggccac acagctggac     3720

gtgacttggg agccacctcc gctggacagc cagaatggag acatccaggg gtacaagatt     3780

tatttctggg aagcccagcg ggggaacctc acagagcgag tgaagacgct tttcctggct     3840

gagaacagcg tgaagctcaa gaacttgact ggctacacgg cctacatggt cagcgtggcc     3900

gccttcaacg ccgctgggga tgggcctcgg agtaccccca cccaaggcca gacccagcaa     3960

gcagccccca gcgctcccag ctcggtcaag ttcagtgagc tgaccacaac ctcagtgaat     4020

gtgtcctggg aagccccgca gttccccaat ggcatcctgg agggctacag gctggtgtac     4080

gagccctgca gccccgtgga tggagtcagc aagatcgtga ccgtggacgt gaaggggaac     4140

agccccctgt ggctgaaggt gaaggacctg gcggaggggg tgacctacag gttccgcatc     4200

agagccaaga ccttcaccta cgggccggag atcgaagcca acgtcaccac gggccccgga     4260

gaaggtgccc caggaccgcc tggcgtgccc atcatcgtgc ggtacagctc tgccatcgcc     4320

attcactggt ccagcggaga cccgggcaaa gggcccatca cccgctacgt catcgaggcc     4380

agaccttcag acgagggact atgggacatc ctcatcaaag acatccccaa ggaggtgagc     4440

tcctacacgt tcagcatgga catcctgaag ccgggcgtga gctatgactt ccgggtcatc     4500

gcggtcaacg actatggttt cggcaccccc agcagcccct cccagtctgt gccagcccag     4560

aaagccaacc ccttctatga ggagtggtgg ttc                                  4593


<210>  4261
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4261
cagaatgaag gctgggacag ccccatctgc acagaggggg tagtctctgt gtcttggggc       60

gagaacaccg tcatgtcctg caacatctcc aacgccttct cccatgtcaa catcaagctg      120

cgtgcccacg ggcaggagag cgccatcttc aatgaggtgg ctccaggcta cttctcccgg      180

gacggctggc agctccaggt tcagggaggc gtggcacagc tggtgatcaa aggcgcccgg      240

gactcccatg ctgggctgta catgtggcac ctcgtgggac accagagaaa taacagacaa      300

gtcacgctgg aggtttcagg tgcagaaccc cagtccgccc ctgacactgg g               351


<210>  4262
<211>  1605
<212>  DNA
<213>  Homo Sapiens

<400>  4262
tggtcttaca acacctccac ggaagctatg acttatgatg aggccagtgc ttattgtcag       60

caaaggtaca cacacctggt tgcaattcaa aacaaagaag agattgagta cctaaactcc      120

atattgagct attcaccaag ttattactgg attggaatca gaaaagtcaa caatgtgtgg      180

gtctgggtag gaacccagaa acctctgaca gaagaagcca agaactgggc tccaggtgaa      240

cccaacaata ggcaaaaaga tgaggactgc gtggagatct acatcaagag agaaaaagat      300

gtgggcatgt ggaatgatga gaggtgcagc aagaagaagc ttgccctatg ctacacagct      360

gcctgtacca atacatcctg cagtggccac ggtgaatgtg tagagaccat caataattac      420

acttgcaagt gtgaccctgg cttcagtgga ctcaagtgtg agcaaattgt gaactgtaca      480

gccctggaat cccctgagca tggaagcctg gtttgcagtc acccactggg aaacttcagc      540

tacaattctt cctgctctat cagctgtgat aggggttacc tgccaagcag catggagacc      600

atgcagtgta tgtcctctgg agaatggagt gctcctattc cagcctgcaa tgtggttgag      660

tgtgatgctg tgacaaatcc agccaatggg ttcgtggaat gtttccaaaa ccctggaagc      720

ttcccatgga acacaacctg tacatttgac tgtgaagaag gatttgaact aatgggagcc      780

cagagccttc agtgtacctc atctgggaat tgggacaacg agaagccaac gtgtaaagct      840

gtgacatgca gggccgtccg ccagcctcag aatggctctg tgaggtgcag ccattcccct      900

gctggagagt tcaccttcaa atcatcctgc aacttcacct gtgaggaagg cttcatgttg      960

cagggaccag cccaggttga atgcaccact caagggcagt ggacacagca aatcccagtt     1020

tgtgaagctt tccagtgcac agccttgtcc aaccccgagc gaggctacat gaattgtctt     1080

cctagtgctt ctggcagttt ccgttatggg tccagctgtg agttctcctg tgagcagggt     1140

tttgtgttga agggatccaa aaggctccaa tgtggcccca caggggagtg ggacaacgag     1200

aagcccacat gtgaagctgt gagatgcgat gctgtccacc agcccccgaa gggtttggtg     1260

aggtgtgctc attcccctat tggagaattc acctacaagt cctcttgtgc cttcagctgt     1320

gaggagggat ttgaattaca tggatcaact caacttgagt gcacatctca gggacaatgg     1380

acagaagagg ttccttcctg ccaagtggta aaatgttcaa gcctggcagt tccgggaaag     1440

atcaacatga gctgcagtgg ggagcccgtg tttggcactg tgtgcaagtt cgcctgtcct     1500

gaaggatgga cgctcaatgg ctctgcagct cggacatgtg gagccacagg acactggtct     1560

ggcctgctac ctacctgtga agctcccact gagtccaaca ttccc                     1605


<210>  4263
<211>  882
<212>  DNA
<213>  Homo Sapiens

<400>  4263
tggacttacc attattctga aaaacccatg aactggcaaa gggctagaag attctgccga       60

gacaattaca cagatttagt tgccatacaa aacaaggcgg aaattgagta tctggagaag      120

actctgcctt tcagtcgttc ttactactgg ataggaatcc ggaagatagg aggaatatgg      180

acgtgggtgg gaaccaacaa atctcttact gaagaagcag agaactgggg agatggtgag      240

cccaacaaca agaagaacaa ggaggactgc gtggagatct atatcaagag aaacaaagat      300

gcaggcaaat ggaacgatga cgcctgccac aaactaaagg cagccctctg ttacacagct      360

tcttgccagc cctggtcatg cagtggccat ggagaatgtg tagaaatcat caataattac      420

acctgcaact gtgatgtggg gtactatggg ccccagtgtc agtttgtgat tcagtgtgag      480

cctttggagg ccccagagct gggtaccatg gactgtactc accctttggg aaacttcagc      540

ttcagctcac agtgtgcctt cagctgctct gaaggaacaa acttaactgg gattgaagaa      600

accacctgtg gaccatttgg aaactggtca tctccagaac caacctgtca agtgattcag      660

tgtgagcctc tatcagcacc agatttgggg atcatgaact gtagccatcc cctggccagc      720

ttcagcttta cctctgcatg taccttcatc tgctcagaag gaactgagtt aattgggaag      780

aagaaaacca tttgtgaatc atctggaatc tggtcaaatc ctagtccaat atgtcaaaaa      840

ttggacaaaa gtttctcaat gattaaggag ggtgattata ac                         882


<210>  4264
<211>  2187
<212>  DNA
<213>  Homo Sapiens

<400>  4264
tggacttatc attacagcac aaaagcatac tcatggaata tttcccgtaa atactgccag       60

aatcgctaca cagacttagt ggccatccag aataaaaatg aaattgatta cctcaataag      120

gtcctaccct actacagctc ctactactgg attgggatcc gaaagaacaa taagacatgg      180

acatgggtgg gaaccaaaaa ggctctcacc aacgaggctg agaactgggc tgataatgaa      240

cctaacaaca aaaggaacaa cgaggactgc gtggagatat acatcaagag tccgtcagcc      300

cctggcaagt ggaatgatga gcactgcttg aagaaaaagc acgcattgtg ttacacagcc      360

tcctgccagg acatgtcctg cagcaaacaa ggagagtgcc tcgagaccat cgggaactac      420

acctgctcct gttaccctgg attctatggg ccagaatgtg aatacgtgag agagtgtgga      480

gaacttgagc tccctcaaca cgtgctcatg aactgcagcc accctctggg aaacttctct      540

tttaactcgc agtgcagctt ccactgcact gacgggtacc aagtaaatgg gcccagcaag      600

ctggaatgct tggcttctgg aatctggaca aataagcctc cacagtgttt agctgcccag      660

tgcccacccc tgaagattcc tgaacgagga aacatgacct gccttcattc tgcaaaagca      720

ttccagcatc agtctagctg cagcttcagt tgtgaagagg gatttgcatt agttggaccg      780

gaagtggtgc aatgcacagc ctcgggggta tggacagccc cagccccagt gtgtaaagct      840

gtgcagtgtc agcacctgga agcccccagt gaaggaacca tggactgtgt tcatccgctc      900

actgcttttg cctatggctc cagctgtaaa tttgagtgcc agcccggcta cagagtgagg      960

ggcttggaca tgctccgctg cattgactct ggacactggt ctgcaccctt gccaacctgt     1020

gaggctattt cgtgtgagcc gctggagagt cctgtccacg gaagcatgga ttgctctcca     1080

tccttgagag cgtttcagta tgacaccaac tgtagcttcc gctgtgctga aggtttcatg     1140

ctgagaggag ccgatatagt tcggtgtgat aacttgggac agtggacagc accagcccca     1200

gtctgtcaag ctttgcagtg ccaggatctc ccagttccaa atgaggcccg ggtgaactgc     1260

tcccacccct tcggtgcctt taggtaccag tcagtctgca gcttcacctg caatgaaggc     1320

ttgctcctgg tgggagcaag tgtgctacag tgcttggcta ctggaaactg gaattctgtt     1380

cctccagaat gccaagccat tccctgcaca cctttgctaa gccctcagaa tggaacaatg     1440

acctgtgttc gacctcttgg aagttccagt tataaatcca catgtcaatt catctgtgac     1500

gagggatatt ctttgtctgg accagaaaga ttggattgta ctcgatcggg acgctggaca     1560

gactccccac caatgtgtga agccatcaag tgcccagaac tctttgcccc agagcagggc     1620

agcctggatt gttctgacac tcgtggagaa ttcaatgttg gctccacctg ccatttctct     1680

tgtaacaacg gctttaagct ggaggggccc aataatgtgg aatgcacaac ttctggaaga     1740

tggtcagcta ctccaccaac ctgcaaaggc atagcatcac ttcctactcc aggggtgcaa     1800

tgtccagccc tcaccactcc tgggcaggga accatgtact gtaggcatca tccgggaacc     1860

tttggtttta ataccacttg ttactttggc tgcaacgctg gattcacact cataggagac     1920

agcactctca gctgcagacc ttcaggacaa tggacagcag taactccagc atgcagagct     1980

gtgaaatgct cagaactaca tgttaataag ccaatagcga tgaactgctc caacctctgg     2040

ggaaacttca gttatggatc aatctgctct ttccattgtc tagagggcca gttacttaat     2100

ggctctgcac aaacagcatg ccaagagaat ggccactggt caactaccgt gccaacctgc     2160

caaggaccat tgactatcca ggaagcc                                         2187


<210>  4265
<211>  2253
<212>  DNA
<213>  Homo Sapiens

<400>  4265
aactatcaga atgggaagaa caatgtgcca aggctgaaat tatcctacaa agaaatgttg       60

gaatccaaca atgtgatcac tttcaatggc ttggccaaca gctccagtta tcataccttc      120

cttttggatg aggaacggag taggctgtat gttggagcaa aggatcacat attttcattc      180

gacctggtta atatcaagga ttttcaaaag attgtgtggc cagtatctta caccagaaga      240

gatgaatgca agtgggctgg aaaagacatc ctgaaagaat gtgctaattt catcaaggta      300

cttaaggcat ataatcagac tcacttgtac gcctgtggaa cgggggcttt tcatccaatt      360

tgcacctaca ttgaaattgg acatcatcct gaggacaata tttttaagct ggagaactca      420

cattttgaaa acggccgtgg gaagagtcca tatgacccta agctgctgac agcatccctt      480

ttaatagatg gagaattata ctctggaact gcagctgatt ttatggggcg agactttgct      540

atcttccgaa ctcttgggca ccaccaccca atcaggacag agcagcatga ttccaggtgg      600

ctcaatgatc caaagttcat tagtgcccac ctcatctcag agagtgacaa tcctgaagat      660

gacaaagtat actttttctt ccgtgaaaat gcaatagatg gagaacactc tggaaaagct      720

actcacgcta gaataggtca gatatgcaag aatgactttg gagggcacag aagtctggtg      780

aataaatgga caacattcct caaagctcgt ctgatttgct cagtgccagg tccaaatggc      840

attgacactc attttgatga actgcaggat gtattcctaa tgaactttaa agatcctaaa      900

aatccagttg tatatggagt gtttacgact tccagtaaca ttttcaaggg atcagccgtg      960

tgtatgtata gcatgagtga tgtgagaagg gtgttccttg gtccatatgc ccacagggat     1020

ggacccaact atcaatgggt gccttatcaa ggaagagtcc cctatccacg gccaggaact     1080

tgtcccagca aaacatttgg tggttttgac tctacaaagg accttcctga tgatgttata     1140

acctttgcaa gaagtcatcc agccatgtac aatccagtgt ttcctatgaa caatcgccca     1200

atagtgatca aaacggatgt aaattatcaa tttacacaaa ttgtcgtaga ccgagtggat     1260

gcagaagatg gacagtatga tgttatgttt atcggaacag atgttgggac cgttcttaaa     1320

gtagtttcaa ttcctaagga gacttggtat gatttagaag aggttctgct ggaagaaatg     1380

acagtttttc gggaaccgac tgctatttca gcaatggagc tttccactaa gcagcaacaa     1440

ctatatattg gttcaacggc tggggttgcc cagctccctt tacaccggtg tgatatttac     1500

gggaaagcgt gtgctgagtg ttgcctcgcc cgagaccctt actgtgcttg ggatggttct     1560

gcatgttctc gctattttcc cactgcaaag agacgcacaa gacgacaaga tataagaaat     1620

ggagacccac tgactcactg ttcagactta caccatgata atcaccatgg ccacagccct     1680

gaagagagaa tcatctatgg tgtagagaat agtagcacat ttttggaatg cagtccgaag     1740

tcgcagagag cgctggtcta ttggcaattc cagaggcgaa atgaagagcg aaaagaagag     1800

atcagagtgg atgatcatat catcaggaca gatcaaggcc ttctgctacg tagtctacaa     1860

cagaaggatt caggcaatta cctctgccat gcggtggaac atgggttcat acaaactctt     1920

cttaaggtaa ccctggaagt cattgacaca gagcatttgg aagaacttct tcataaagat     1980

gatgatggag atggctctaa gaccaaagaa atgtccaata gcatgacacc tagccagaag     2040

gtctggtaca gagacttcat gcagctcatc aaccacccca atctcaacac gatggatgag     2100

ttctgtgaac aagtttggaa aagggaccga aaacaacgtc ggcaaaggcc aggacatacc     2160

ccagggaaca gtaacaaatg gaagcactta caagaaaata agaaaggtag aaacaggagg     2220

acccacgaat ttgagagggc acccaggagt gtc                                  2253


<210>  4266
<211>  2172
<212>  DNA
<213>  Homo Sapiens

<400>  4266
gcccccagcc ccccacgcct tcggctctcc ttccaagagc tccaggcctg gcatggtctc       60

cagactttca gcctggagcg aacctgctgc taccaggcct tgctggtgga tgaggagcgt      120

ggacgcctgt ttgtgggtgc cgagaaccat gtggcctccc tcaacctgga caacatcagc      180

aagcgggcca agaagctggc ctggccggcc cctgtggaat ggcgagagga gtgcaactgg      240

gcagggaagg acattggtac tgagtgcatg aacttcgtga agttgctgca tgcctacaac      300

cgcacccatt tgctggcctg tggcacggga gccttccacc caacctgtgc ctttgtggaa      360

gtgggccacc gggcagagga gcccgtcctc cggctggacc caggaaggat agaggatggc      420

aaggggaaga gtccttatga ccccaggcat cgggctgcct ccgtgctggt gggggaggag      480

ctatactcag gggtggcagc agacctcatg ggacgagact ttaccatctt tcgcagccta      540

gggcaacgtc caagtctccg aacagagcca cacgactccc gctggctcaa tgagcccaag      600

tttgtcaagg tattttggat cccggagagc gagaacccag acgacgacaa aatctacttc      660

ttctttcgtg agacggcggt agaggcggcg ccggcactgg gacgcctgtc cgtgtcccgc      720

gttggccaga tctgccggaa cgacgtgggc ggccagcgca gcctggtcaa caagtggacg      780

acgttcctga aggcgcggct ggtgtgctcg gtgcccggcg tcgagggcga cacccacttc      840

gatcagctcc aggatgtgtt tctgttgtcc tcgcgggacc accggacccc gctgctctat      900

gccgtcttct ccacgtccag catcttccag ggctctgcgg tgtgcgtgta cagcatgaac      960

gacgtgcgcc gggccttctt gggacccttt gcacacaagg aggggcccat gcaccagtgg     1020

gtgtcatacc agggtcgcgt cccctacccg cggccaggca tgtgccccag caagaccttt     1080

ggcaccttca gttccaccaa ggacttccca gacgatgtca tccagtttgc gcggaaccac     1140

cccctcatgt acaactctgt cctgcccact ggggggcgcc ctcttttcct acaagttgga     1200

gccaattaca ccttcactca aattgccgcg gaccgggttg cagccgctga cggacactat     1260

gacgtcctct tcattggcac agacgttggc acggtgctga aggtgatctc ggtccccaag     1320

ggcagtaggc ccagcgcaga ggggctgctc ctggaggagc tgcacgtgtt tgaggactcg     1380

gccgctgtca ccagcatgca aatttcttcc aagaggcacc agctgtacgt agcctcgcgg     1440

agcgcggtgg cccagatcgc gttgcaccgc tgcgctgccc acggccgcgt ctgcaccgaa     1500

tgctgtctgg cgcgtgaccc ctactgcgcc tgggacgggg tcgcgtgcac gcgcttccag     1560

cccagtgcca agaggcggtt ccggcggcaa gacgtaagga atggcgaccc cagcacgttg     1620

tgctccggag actcgtctcg tcccgcgctg ctggaacaca aggtgttcgg cgtggagggc     1680

agcagcgcct ttctggagtg tgagccccgc tcgctgcagg cgcgcgtgga gtggactttc     1740

cagcgcgcag gggtgacagc ccacacccag gtgctggcag aggagcgcac cgagcgcacc     1800

gcccggggac tactgctgcg caggctgcgg cgccgggact cgggcgtgta cttgtgcgcc     1860

gccgtcgagc agggctttac gcaaccgctg cgtcgcctgt cgctgcacgt gttgagtgct     1920

acgcaggccg aacgactggc gcgggccgag gaggctgcgc ccgccgcgcc gccgggcccc     1980

aaactctggt accgggactt tctgcagctg gtggagccgg gcggaggtgg cagcgcgaac     2040

tccctgcgca tgtgccgccc gcagcctgcg ctgcagtcac tgcccctgga gtcgcggaga     2100

aagggccgta accggaggac ccacgcccct gagcctcgcg ctgagcgggg gccgcgcagc     2160

gcaacgcact gg                                                         2172


<210>  4267
<211>  2193
<212>  DNA
<213>  Homo Sapiens

<400>  4267
ggatcttccc agccccaagc aagagtttat ttaacatttg atgaacttcg agaaaccaag       60

acctctgaat acttcagcct ttcccaccat cctttagact acaggatttt attaatggat      120

gaagatcagg accggatata tgtgggaagc aaagatcaca ttctttccct gaatattaac      180

aatataagtc aagaagcttt gagtgttttc tggccagcat ctacaatcaa agttgaagaa      240

tgcaaaatgg ctggcaaaga tcccacacac ggctgtggga actttgtccg tgtaattcag      300

actttcaatc gcacacattt gtatgtctgt gggagtggcg ctttcagtcc tgtctgtact      360

tacttgaaca gagggaggag atcagaggac caagttttca tgattgactc caagtgtgaa      420

tctggaaaag gacgctgctc tttcaacccc aacgtgaaca cggtgtctgt tatgatcaat      480

gaggagcttt tctctggaat gtatatagat ttcatgggga cagatgctgc tatttttcga      540

agtttaacca agaggaatgc ggtcagaact gatcaacata attccaaatg gctaagtgaa      600

cctatgtttg tagatgcaca tgtcatccca gatggtactg atccaaatga tgctaaggtg      660

tacttcttct tcaaagaaaa actgactgac aataacagga gcacgaaaca gattcattcc      720

atgattgctc gaatatgtcc taatgacact ggtggactgc gtagccttgt caacaagtgg      780

accactttct taaaggcgag gctggtgtgc tcggtaacag atgaagacgg cccagaaaca      840

cactttgatg aattagagga tgtgtttctg ctggaaactg ataacccgag gacaacacta      900

gtgtatggca tttttacaac atcaagctca gttttcaaag gatcagccgt gtgtgtgtat      960

catttatctg atatacagac tgtgtttaat gggccttttg cccacaaaga agggcccaat     1020

catcagctga tttcctatca gggcagaatt ccatatcctc gccctggaac ttgtccagga     1080

ggagcattta cacccaatat gcgaaccacc aaggagttcc cagatgatgt tgtcactttt     1140

attcggaacc atcctctcat gtacaattcc atctacccaa tccacaaaag gcctttgatt     1200

gttcgtattg gcactgacta caagtacaca aagatagctg tggatcgagt gaacgctgct     1260

gatgggagat accatgtcct gtttctcgga acagatcggg gtactgtgca aaaagtggtt     1320

gttcttccta ctaacaactc tgtcagtggc gagctcattc tggaggagct ggaagtcttt     1380

aagaatcatg ctcctataac aacaatgaaa atttcatcta aaaagcaaca gttgtatgtg     1440

agttccaatg aaggggtttc ccaggtatct ctgcaccgct gccacatcta tggtacagcc     1500

tgtgctgact gctgcctggc gcgggaccct tattgcgcct gggatggcca ttcctgttcc     1560

agattctacc caactgggaa acggaggagc cgaagacaag atgtgagaca tggaaaccca     1620

ctgactcaat gcagaggatt taatctaaaa gcatacagaa atgcagctga aattgtgcag     1680

tatggagtaa aaaataacac cacttttctg gagtgtgccc ccaagtctcc gcaggcatct     1740

atcaagtggc tgttacagaa agacaaagac aggaggaaag aggttaagct gaatgaacga     1800

ataatagcca cttcacaggg actcctgatc cgctctgttc agggttctga ccaaggactt     1860

tatcactgca ttgctacaga aaatagtttc aagcagacca tagccaagat caacttcaaa     1920

gttttagatt cagaaatggt ggctgttgtg acggacaaat ggtccccgtg gacctgggcc     1980

agctctgtga gggctttacc cttccacccg aaggacatca tgggggcatt cagccactca     2040

gaaatgcaga tgattaacca atactgcaaa gacactcggc agcaacatca gcagggagat     2100

gaatcacaga aaatgagagg ggactatggc aagttaaagg ccctcatcaa tagtcggaaa     2160

agtagaaaca ggaggaatca gttgccagag tca                                  2193


<210>  4268
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  4268
agatgcgaca cttatgggaa agcttgcgca gactgttgtc ttgccagaga cccctactgt       60

gcctgggatg gaaatgcatg ctctcgatat gctcctactt ctaaaaggag agctagacgc      120

caagatgtaa aatatggcga cccaatcacc cagtgctggg acatcgaaga cagcattagt      180

catgaaactg ctgatgaaaa ggtgattttt ggcattgaat ttaactcaac ctttctggaa      240

tgtataccta aatcccaaca agcaactatt aaatggtata tccagaggtc aggggatgag      300

catcgagagg agttgaagcc cgatgaaaga atcatcaaaa cggaatatgg gctactgatt      360

cgaagtttgc agaagaagga ttctgggatg tattactgca aagcccagga gcacactttc      420

atccacacca tagtgaagct gactttgaat gtcattgaga atgaacagat ggaaaatacc      480

cagagggcag agcatgagga ggggaaggtc aaggatctat tggctgagtc acggttgaga      540

tacaaagact acatccaaat ccttagcagc ccaaacttca gcctcgacca gtactgcgaa      600

cagatgtggc acagggagaa gcggagacag agaaacaagg ggggcccaaa gtggaagcac      660

atgcaggaaa tgaagaagaa acgaaatcga agacatcaca gagacctgga tgagctccct      720

agagctgtag ccacg                                                       735


<210>  4269
<211>  2250
<212>  DNA
<213>  Homo Sapiens

<400>  4269
gctgatacta cccacccccg gttacgcctg tcacataaag agctcttgaa tctgaacaga       60

acatcaatat ttcatagccc ttttggattt cttgatctcc atacaatgct gctggatgaa      120

tatcaagaga ggctcttcgt gggaggcagg gaccttgtat attccctcag cttggagaga      180

atcagtgacg gctataaaga gatacactgg ccgagtacag ctctaaaaat ggaagaatgc      240

ataatgaagg gaaaagatgc gggtgaatgt gcaaattatg ttcgggtttt gcatcactat      300

aacaggacac accttctgac ctgtggtact ggagcttttg atccagtttg tgccttcatc      360

agagttggat atcatttgga ggatcctctg tttcacctgg aatcacccag atctgagaga      420

ggaaggggca gatgtccttt tgaccccagc tcctccttca tctccacttt aattggtagt      480

gaattgtttg ctggactcta cagtgactac tggagcagag acgctgcgat cttccgcagc      540

atggggcgac tggcccatat ccgcactgag catgacgatg agcgtctgtt gaaagaacca      600

aaatttgtag gttcatacat gattcctgac aatgaagaca gagatgacaa caaagtatat      660

ttctttttta ctgagaaggc actggaggca gaaaacaatg ctcacgcaat ttacaccagg      720

gtcgggcgac tctgtgtgaa tgatgtagga gggcagagaa tactggtgaa taagtggagc      780

actttcctaa aagcgagact cgtttgctca gtaccaggaa tgaatggaat tgacacatat      840

tttgatgaat tagaggacgt ttttttgcta cctaccagag atcataagaa tccagtgata      900

tttggactct ttaacactac cagtaatatt tttcgagggc atgctatatg tgtctatcac      960

atgtctagca ttcgggcagc cttcaacgga ccatatgcac ataaggaagg acctgaatac     1020

cactggtcag tctatgaagg aaaagtccct tatccaaggc ctggttcttg tgccagcaaa     1080

gtaaatggag ggagatacgg aaccaccaag gactatcctg atgatgccat ccgatttgca     1140

agaagtcatc cactaatgta ccaggccata aaacctgccc ataaaaaacc aatattggta     1200

aaaacagatg gaaaatataa cctgaaacaa atagcagtag atcgagtgga agctgaggat     1260

ggccaatatg acgtcttgtt tattgggaca gataatggaa ttgtgctgaa agtaatcaca     1320

atttacaacc aagaaatgga atcaatggaa gaagtaattc tagaagaact tcagatattc     1380

aaggatccag ttcctattat ttctatggag atttcttcaa aacggcaaca gctgtatatt     1440

ggatctgctt ctgctgtggc tcaagtcaga ttccatcact gtgacatgta tggaagtgct     1500

tgtgctgact gctgcctggc tcgagaccct tactgtgcct gggatggcat atcctgctcc     1560

cggtattacc caacaggcac acatgcaaaa aggcgtttcc ggagacaaga tgttcgacat     1620

ggaaatgcag ctcagcagtg ctttggacaa cagtttgttg gggatgcttt ggataagact     1680

gaagaacatc tggcttatgg catagagaac aacagtactt tgctggaatg taccccacga     1740

tctttacaag cgaaagttat ctggtttgta cagaaaggac gtgagacaag aaaagaggag     1800

gtgaagacag atgacagagt ggttaagatg gaccttggtt tactcttcct aaggttacac     1860

aaatcagatg ctgggaccta tttttgccag acagtagagc atagctttgt ccatacggtc     1920

cgtaaaatca ccttggaggt agtggaagag gagaaagtcg aggatatgtt taacaaggac     1980

gatgaggagg acaggcatca caggatgcct tgtcctgctc agagtagcat ctcgcaggga     2040

gcaaaaccat ggtacaagga attcttgcag ctgatcggtt atagcaactt ccagagagtg     2100

gaagaatact gcgagaaagt atggtgcaca gatagaaaga ggaaaaagct taaaatgtca     2160

ccctccaagt ggaagtatgc caaccctcag gaaaagaagc tccgttccaa acctgagcat     2220

taccgcctgc ccaggcacac gctggactcc                                      2250


<210>  4270
<211>  2301
<212>  DNA
<213>  Homo Sapiens

<400>  4270
tccttcccca cccaggacca cctcccggcc acgccccggg tccggctctc attcaaagag       60

ctgaaggcca caggcaccgc ccacttcttc aacttcctgc tcaacacaac cgactaccga      120

atcttgctca aggacgagga ccacgaccgc atgtacgtgg gcagcaagga ctacgtgctg      180

tccctggacc tgcacgacat caaccgcgag cccctcatta tacactgggc agcctcccca      240

cagcgcatcg aggaatgcgt gctctcaggc aaggatgtca acggcgagtg tgggaacttc      300

gtcaggctca tccagccctg gaaccgaaca cacctgtatg tgtgcgggac aggtgcctac      360

aaccccatgt gcacctatgt gaaccgcgga cgccgcgccc aggccacacc atggacccag      420

actcaggcgg tcagaggccg cggcagcaga gccacggatg gtgccctccg cccgatgccc      480

acagccccac gccaggatta catcttctac ctggagcctg agcgactcga gtcagggaag      540

ggcaagtgtc cgtacgatcc caagctggac acagcatcgg ccctcatcaa tgaggagctc      600

tatgctggtg tgtacatcga ttttatgggc actgatgcag ccatcttccg cacacttgga      660

aagcagacag ccatgcgcac ggatcagtac aactcccggt ggctgaacga cccgtcgttc      720

atccatgctg agctcattcc tgacagtgcg gagcgcaatg atgataagct ttacttcttc      780

ttccgtgagc ggtcggcaga ggcgccgcag agccccgcgg tgtacgcccg catcgggcgc      840

atttgcctga acgatgacgg tggtcactgt tgcctggtca acaagtggag cacattcctg      900

aaggcgcggc tcgtctgctc tgtcccgggc gaggatggca ttgagactca ctttgatgag      960

ctccaggacg tgtttgtcca gcagacccag gacgtgagga accctgtcat ttacgctgtc     1020

tttacctcct ctggctccgt gttccgaggc tctgccgtgt gtgtctactc catggctgat     1080

attcgcatgg tcttcaacgg gccctttgcc cacaaagagg ggcccaacta ccagtggatg     1140

cccttctcag ggaagatgcc ctacccacgg ccgggcacgt gccctggtgg aaccttcacg     1200

ccatctatga agtccaccaa ggattatcct gatgaggtga tcaacttcat gcgcagccac     1260

ccactcatgt accaggccgt gtaccctctg cagcggcggc ccctggtagt ccgcacaggt     1320

gctccctacc gccttaccac tattgccgtg gaccaggtgg atgcagccga cgggcgctat     1380

gaggtgcttt tcctgggcac agaccgcggg acagtgcaga aggtcattgt gctgcccaag     1440

gatgaccagg agatggagga gctcatgctg gaggaggtgg aggtcttcaa ggatccagca     1500

cccgtcaaga ccatgaccat ctcttctaag aggcaacaac tctacgtggc gtcagccgtg     1560

ggtgtcacac acctgagcct gcaccgctgc caggcgtatg gggctgcctg tgctgactgc     1620

tgccttgccc gggaccctta ctgtgcctgg gatggccagg cctgctcccg ctatacagca     1680

tcctccaaga ggcggagccg ccggcaggac gtccggcacg gaaaccccat caggcagtgc     1740

cgtgggttca actccaatgc caacaagaat gccgtggagt ctgtgcagta tggcgtggcc     1800

ggcagcgcag ccttccttga gtgccagccc cgctcgcccc aagccactgt taagtggctg     1860

ttccagcgag atcctggtga ccggcgccga gagattcgtg cagaggaccg cttcctgcgc     1920

acagagcagg gcttgttgct ccgtgcactg cagctcagcg atcgtggcct ctactcctgc     1980

acagccactg agaacaactt taagcacgtc gtcacacgag tgcagctgca tgtactgggc     2040

cgggacgccg tccatgctgc cctcttccca ccactgtcca tgagcgcccc gccaccccca     2100

ggcgcaggcc ccccaacgcc tccttaccag gagttagccc agctgctggc ccagccagaa     2160

gtgggcctca tccaccagta ctgccagggt tactggcgcc atgtgccccc cagccccagg     2220

gaggctccag gggcaccccg gtctcctgag ccccaggacc agaaaaagcc ccggaaccgc     2280

cggcaccacc ctccggacac a                                               2301


<210>  4271
<211>  2280
<212>  DNA
<213>  Homo Sapiens

<400>  4271
ggccccagcc ccggccccag tgtgccccgc ctgcggctct cctaccgaga cctcctgtct       60

gccaaccgct ctgccatctt tctgggcccc cagggctccc tgaacctcca ggccatgtac      120

ctagatgagt accgagaccg cctctttctg ggtggcctgg acgccctcta ctctctgcgg      180

ctggaccagg catggccaga tccccgggag gtcctgtggc caccgcagcc aggacagagg      240

gaggagtgtg ttcgaaaggg aagagatcct ttgacagagt gcgccaactt cgtgcgggtg      300

ctacagcctc acaaccggac ccacctgcta gcctgtggca ctggggcctt ccagcccacc      360

tgtgccctca tcacagttgg ccaccgtggg gagcatgtgc tccacctgga gcctggcagt      420

gtggaaagtg gccgggggcg gtgccctcac gagcccagcc gtccctttgc cagcaccttc      480

atagacgggg agctgtacac gggtctcact gctgacttcc tggggcgaga ggccatgatc      540

ttccgaagtg gaggtcctcg gccagctctg cgttccgact ctgaccagag tctcttgcac      600

gacccccggt ttgtgatggc cgcccggatc cctgagaact ctgaccagga caatgacaag      660

gtgtacttct tcttctcgga gacggtcccc tcgcccgatg gtggctcgaa ccatgtcact      720

gtcagccgcg tgggccgcgt ctgcgtgaat gatgctgggg gccagcgggt gctggtgaac      780

aaatggagca ctttcctcaa ggccaggctg gtctgctcgg tgcccggccc tggtggtgcc      840

gagacccact ttgaccagct agaggatgtg ttcctgctgt ggcccaaggc cgggaagagc      900

ctcgaggtgt acgcgctgtt cagcaccgtc agtgccgtgt tccagggctt cgccgtctgt      960

gtgtaccaca tggcagacat ctgggaggtt ttcaacgggc cctttgccca ccgagatggg     1020

cctcagcacc agtgggggcc ctatgggggc aaggtgccct tccctcgccc tggcgtgtgc     1080

cccagcaaga tgaccgcaca gccaggacgg ccttttggca gcaccaagga ctacccagat     1140

gaggtgctgc agtttgcccg agcccacccc ctcatgttct ggcctgtgcg gcctcgacat     1200

ggccgccctg tccttgtcaa gacccacctg gcccagcagc tacaccagat cgtggtggac     1260

cgcgtggagg cagaggatgg gacctacgat gtcattttcc tggggactga ctcagggtct     1320

gtgctcaaag tcatcgctct ccaggcaggg ggctcagctg aacctgagga agtggttctg     1380

gaggagctcc aggtgtttaa ggtgccaaca cctatcaccg aaatggagat ctctgtcaaa     1440

aggcaaatgc tatacgtggg ctctcggctg ggtgtggccc agctgcggct gcaccaatgt     1500

gagacttacg gcactgcctg tgcagagtgc tgcctggccc gggacccata ctgtgcctgg     1560

gatggtgcct cctgtaccca ctaccgcccc agccttggca agcgccggtt ccgccggcag     1620

gacatccggc acggcaaccc tgccctgcag tgcctgggcc agagccagga agaagaggca     1680

gtgggacttg tggcagccac catggtctac ggcacggagc acaatagcac cttcctggag     1740

tgcctgccca agtctcccca ggctgctgtg cgctggctct tgcagaggcc aggggatgag     1800

gggcctgacc aggtgaagac ggacgagcga gtcttgcaca cggagcgggg gctgctgttc     1860

cgcaggctta gccgtttcga tgcgggcacc tacacctgca ccactctgga gcatggcttc     1920

tcccagactg tggtccgcct ggctctggtg gtgattgtgg cctcacagct ggacaacctg     1980

ttccctccgg agccaaagcc agaggagccc ccagcccggg gaggcctggc ttccacccca     2040

cccaaggcct ggtacaagga catcctgcag ctcattggct tcgccaacct gccccgggtg     2100

gatgagtact gtgagcgcgt gtggtgcagg ggcaccacgg aatgctcagg ctgcttccgg     2160

agccggagcc ggggcaagca ggccaggggc aagagctggg cagggctgga gctaggcaag     2220

aagatgaaga gccgggtgca tgccgagcac aatcggacgc cccgggaggt ggaggccacg     2280


<210>  4272
<211>  1953
<212>  DNA
<213>  Homo Sapiens

<400>  4272
ggaggcgggc aggggcccat gcccagggtc agatactatg caggggatga acgtagggca       60

cttagcttct tccaccagaa gggcctccag gattttgaca ctctgctcct gagtggtgat      120

ggaaatactc tctacgtggg ggctcgagaa gccattctgg ccttggatat ccaggatcca      180

ggggtcccca ggctaaagaa catgataccg tggccagcca gtgacagaaa aaagagtgaa      240

tgtgccttta agaagaagag caatgagaca cagtgtttca acttcatccg tgtcctggtt      300

tcttacaatg tcacccatct ctacacctgc ggcaccttcg ccttcagccc tgcttgtacc      360

ttcattgaac ttcaagattc ctacctgttg cccatctcgg aggacaaggt catggaggga      420

aaaggccaaa gcccctttga ccccgctcac aagcatacgg ctgtcttggt ggatgggatg      480

ctctattctg gtactatgaa caacttcctg ggcagtgagc ccatcctgat gcgcacactg      540

ggatcccagc ctgtcctcaa gaccgacaac ttcctccgct ggctgcatca tgacgcctcc      600

tttgtggcag ccatcccttc gacccaggtc gtctacttct tcttcgagga gacagccagc      660

gagtttgact tctttgagag gctccacaca tcgcgggtgg ctagagtctg caagaatgac      720

gtgggcggcg aaaagctgct gcagaagaag tggaccacct tcctgaaggc ccagctgctc      780

tgcacccagc cggggcagct gcccttcaac gtcatccgcc acgcggtcct gctccccgcc      840

gattctccca cagctcccca catctacgca gtcttcacct cccagtggca ggttggcggg      900

accaggagct ctgcggtttg tgccttctct ctcttggaca ttgaacgtgt ctttaagggg      960

aaatacaaag agttgaacaa agaaacttca cgctggacta cttatagggg ccctgagacc     1020

aacccccggc caggcagttg ctcagtgggc ccctcctctg ataaggccct gaccttcatg     1080

aaggaccatt tcctgatgga tgagcaagtg gtggggacgc ccctgctggt gaaatctggc     1140

gtggagtata cacggcttgc agtggagaca gcccagggcc ttgatgggca cagccatctt     1200

gtcatgtacc tgggaaccac cacagggtcg ctccacaagg ctgtggtaag tggggacagc     1260

agtgctcatc tggtggaaga gattcagctg ttccctgacc ctgaacctgt tcgcaacctg     1320

cagctggccc ccacccaggg tgcagtgttt gtaggcttct caggaggtgt ctggagggtg     1380

ccccgagcca actgtagtgt ctatgagagc tgtgtggact gtgtccttgc ccgggacccc     1440

cactgtgcct gggaccctga gtcccgaacc tgttgcctcc tgtctgcccc caacctgaac     1500

tcctggaagc aggacatgga gcgggggaac ccagagtggg catgtgccag tggccccatg     1560

agcaggagcc ttcggcctca gagccgcccg caaatcatta aagaagtcct ggctgtccct     1620

aactccatcc tggagctccc ctgcccccac ctgtcagcct tggcctctta ttattggagt     1680

catggcccag cagcagtccc agaagcctct tccactgtct acaatggctc cctcttgctg     1740

atagtgcagg atggagttgg gggtctctac cagtgctggg caactgagaa tggcttttca     1800

taccctgtga tctcctactg ggtggacagc caggaccaga ccctggccct ggatcctgaa     1860

ctggcaggca tcccccggga gcatgtgaag gtcccgttga ccagggtcag tggtggggcc     1920

gccctggctg cccagcagtc ctactggccc cac                                  1953


<210>  4273
<211>  2022
<212>  DNA
<213>  Homo Sapiens

<400>  4273
ctcagccccc ggatcagcct gcctctgggc tctgaagagc ggccattcct cagattcgaa       60

gctgaacaca tctccaacta cacagccctt ctgctgagca gggatggcag gaccctgtac      120

gtgggtgctc gagaggccct ctttgcactc agtagcaacc tcagcttcct gccaggcggg      180

gagtaccagg agctgctttg gggtgcagac gcagagaaga aacagcagtg cagcttcaag      240

ggcaaggacc cacagcgcga ctgtcaaaac tacatcaaga tcctcctgcc gctcagcggc      300

agtcacctgt tcacctgtgg cacagcagcc ttcagcccca tgtgtaccta catcaacatg      360

gagaacttca ccctggcaag ggacgagaag gggaatgtcc tcctggaaga tggcaagggc      420

cgttgtccct tcgacccgaa tttcaagtcc actgccctgg tggttgatgg cgagctctac      480

actggaacag tcagcagctt ccaagggaat gacccggcca tctcgcggag ccaaagcctt      540

cgccccacca agaccgagag ctccctcaac tggctgcaag acccagcttt tgtggcctca      600

gcctacattc ctgagagcct gggcagcttg caaggcgatg atgacaagat ctactttttc      660

ttcagcgaga ctggccagga atttgagttc tttgagaaca ccattgtgtc ccgcattgcc      720

cgcatctgca agggcgatga gggtggagag cgggtgctac agcagcgctg gacctccttc      780

ctcaaggccc agctgctgtg ctcacggccc gacgatggct tccccttcaa cgtgctgcag      840

gatgtcttca cgctgagccc cagcccccag gactggcgtg acaccctttt ctatggggtc      900

ttcacttccc agtggcacag gggaactaca gaaggctctg ccgtctgtgt cttcacaatg      960

aaggatgtgc agagagtctt cagcggcctc tacaaggagg tgaaccgtga gacacagcag     1020

tggtacaccg tgacccaccc ggtgcccaca ccccggcctg gagcgtgcat caccaacagt     1080

gcccgggaaa ggaagatcaa ctcatccctg cagctcccag accgcgtgct gaacttcctc     1140

aaggaccact tcctgatgga cgggcaggtc cgaagccgca tgctgctgct gcagccccag     1200

gctcgctacc agcgcgtggc tgtacaccgc gtccctggcc tgcaccacac ctacgatgtc     1260

ctcttcctgg gcactggtga cggccggctc cacaaggcag tgagcgtggg cccccgggtg     1320

cacatcattg aggagctgca gatcttctca tcgggacagc ccgtgcagaa tctgctcctg     1380

gacacccaca gggggctgct gtatgcggcc tcacactcgg gcgtagtcca ggtgcccatg     1440

gccaactgca gcctgtaccg gagctgtggg gactgcctcc tcgcccggga cccctactgt     1500

gcttggagcg gctccagctg caagcacgtc agcctctacc agcctcagct ggccaccagg     1560

ccgtggatcc aggacatcga gggagccagc gccaaggacc tttgcagcgc gtcttcggtt     1620

gtgtccccgt cttttgtacc aacaggggag aagccatgtg agcaagtcca gttccagccc     1680

aacacagtga acactttggc ctgcccgctc ctctccaacc tggcgacccg actctggcta     1740

cgcaacgggg cccccgtcaa tgcctcggcc tcctgccacg tgctacccac tggggacctg     1800

ctgctggtgg gcacccaaca gctgggggag ttccagtgct ggtcactaga ggagggcttc     1860

cagcagctgg tagccagcta ctgcccagag gtggtggagg acggggtggc agaccaaaca     1920

gatgagggtg gcagtgtacc cgtcattatc agcacatcgc gtgtgagtgc accagctggt     1980

ggcaaggcca gctggggtgc agacaggtcc tactggaagg ag                        2022


<210>  4274
<211>  1929
<212>  DNA
<213>  Homo Sapiens

<400>  4274
gctgaggtgt ggtggaacct tgtgccgcgt aagacagtgt cttctgggga gctggccacg       60

gtagtacggc ggttctccca gaccggcatc caggacttcc tgacactgac gctgacggag      120

cccactgggc ttctgtacgt gggcgcccga gaggccctgt ttgccttcag catggaggcc      180

ctggagctgc aaggagcgat ctcctgggag gcccccgtgg agaagaagac tgagtgtatc      240

cagaaaggga agaacaacca gaccgagtgc ttcaacttca tccgcttcct gcagccctac      300

aatgcctccc acctgtacgt ctgtggcacc tacgccttcc agcccaagtg cacctacgtc      360

aacatgctca ccttcacttt ggagcatgga gagtttgaag atgggaaggg caagtgtccc      420

tatgacccag ctaagggcca tgctggcctt cttgtggatg gtgagctgta ctcggccaca      480

ctcaacaact tcctgggcac ggaacccatt atcctgcgta acatggggcc ccaccactcc      540

atgaagacag agtacctggc cttttggctc aacgaacctc actttgtagg ctctgcctat      600

gtacctgaga gtgtgggcag cttcacgggg gacgacgaca aggtctactt cttcttcagg      660

gagcgggcag tggagtccga ctgctatgcc gagcaggtgg tggctcgtgt ggcccgtgtc      720

tgcaagggcg atatgggggg cgcacggacc ctgcagagga agtggaccac gttcctgaag      780

gcgcggctgg catgctctgc cccgaactgg cagctctact tcaaccagct gcaggcgatg      840

cacaccctgc aggacacctc ctggcacaac accaccttct ttggggtttt tcaagcacag      900

tggggtgaca tgtacctgtc ggccatctgt gagtaccagt tggaagagat ccagcgggtg      960

tttgagggcc cctataagga gtaccatgag gaagcccaga agtgggaccg ctacactgac     1020

cctgtaccca gccctcggcc tggctcgtgc attaacaact ggcatcggcg ccacggctac     1080

accagctccc tggagctacc cgacaacatc ctcaacttcg tcaagaagca cccgctgatg     1140

gaggagcagg tggggcctcg gtggagccgc cccctgctcg tgaagaaggg caccaacttc     1200

acccacctgg tggccgaccg ggttacagga cttgatggag ccacctatac agtgctgttc     1260

attggcacag gagacggctg gctgctcaag gctgtgagcc tggggccctg ggttcacctg     1320

attgaggagc tgcagctgtt tgaccaggag cccatgagaa gcctggtgct atctcagagc     1380

aagaagctgc tctttgccgg ctcccgctct cagctggtgc agctgcccgt ggccgactgc     1440

atgaagtatc gctcctgtgc agactgtgtc ctcgcccggg acccctattg cgcctggagc     1500

gtcaacacca gccgctgtgt ggccgtgggt ggccactctg gatctctact gatccagcat     1560

gtgatgacct cggacacttc aggcatctgc aacctccgtg gcagtaagaa agtcaggccc     1620

actcccaaaa acatcacggt ggtggcgggc acagacctgg tgctaccctg ccacctctcc     1680

tccaacttgg cccatgcccg ctggaccttt gggggccggg acctgcctgc ggaacagccc     1740

gggtccttcc tctacgatgc ccggctccag gccctggttg tgatggctgc ccagccccgc     1800

catgccgggg cctaccactg cttttcagag gagcaggggg cgcggctggc tgctgaaggc     1860

taccttgtgg ctgtcgtggc aggcccgtcg gtgaccttgg aggcccgggc ccccctggaa     1920

aacctgggg                                                             1929


<210>  4275
<211>  2139
<212>  DNA
<213>  Homo Sapiens

<400>  4275
atggcatttg cacccatacc ccggatcacc tgggagcaca gagaggtgca cctggtgcag       60

tttcatgagc cagacatcta caactactca gccttgctgc tgagcgagga caaggacacc      120

ttgtacatag gtgcccggga ggcggtcttc gctgtgaacg cactcaacat ctccgagaag      180

cagcatgagg tgtattggaa ggtctcagaa gacaaaaaag caaaatgtgc agaaaagggg      240

aaatcaaaac agacagagtg cctcaactac atccgggtgc tgcagccact cagcgccact      300

tccctttacg tgtgtgggac caacgcattc cagccggcct gtgaccacct gaacttaaca      360

tcctttaagt ttctggggaa aaatgaagat ggcaaaggaa gatgtccctt tgacccagca      420

cacagctaca catccgtcat ggttgatgga gaactttatt cggggacgtc gtataatttt      480

ttgggaagtg aacccatcat ctcccgaaat tcttcccaca gtcctctgag gacagaatat      540

gcaatccctt ggctgaacga gcctagtttc gtgtttgctg acgtgatccg aaaaagccca      600

gacagccccg acggcgagga tgacagggtc tacttcttct tcacggaggt gtctgtggag      660

tatgagtttg tgttcagggt gctgatccca cggatagcaa gagtgtgcaa gggggaccag      720

ggcggcctga ggaccttgca gaagaaatgg acctccttcc tgaaagcccg actcatctgc      780

tcccggccag acagcggctt ggtcttcaat gtgctgcggg atgtcttcgt gctcaggtcc      840

ccgggcctga aggtgcctgt gttctatgca ctcttcaccc cacagctgaa caacgtgggg      900

ctgtcggcag tgtgcgccta caacctgtcc acagccgagg aggtcttctc ccacgggaag      960

tacatgcaga gcaccacagt ggagcagtcc cacaccaagt gggtgcgcta taatggcccg     1020

gtacccaagc cgcggcctgg agcgtgcatc gacagcgagg cacgggccgc caactacacc     1080

agctccttga atttgccaga caagacgctg cagttcgtta aagaccaccc tttgatggat     1140

gactcggtaa ccccaataga caacaggccc aggttaatca agaaagatgt gaactacacc     1200

cagatcgtgg tggaccggac ccaggccctg gatgggactg tctatgatgt catgtttgtc     1260

agcacagacc ggggagctct gcacaaagcc atcagcctcg agcacgctgt tcacatcatc     1320

gaggagaccc agctcttcca ggactttgag ccagtccaga ccctgctgct gtcttcaaag     1380

aagggcaaca ggtttgtcta tgctggctct aactcgggcg tggtccaggc cccgctggcc     1440

ttctgtggga agcacggcac ctgcgaggac tgtgtgctgg cgcgggaccc ctactgcgcc     1500

tggagcccgc ccacagcgac ctgcgtggct ctgcaccaga ccgagagccc cagcaggggt     1560

ttgattcagg agatgagcgg cgatgcttct gtgtgcccgg ataaaagtaa aggaagttac     1620

cggcagcatt ttttcaagca cggtggcaca gcggaactga aatgctccca aaaatccaac     1680

ctggcccggg tcttttggaa gttccagaat gacgtgttga aggccgagag ccccaagtac     1740

ggtcttatgg gcagaaaaaa cttgctcatc ttcaacttgt cagaaggaga cagtggggtg     1800

taccagtgcc tgtcagagga gagggttaag aacaaaacgg tcttccaagt ggtcgccaag     1860

cacgtcctgg aagtgaaggt ggttccaaag cccgtagtgg cccccacctt gtcagttgtt     1920

cagacagaag gtagtaggat tgccaccaaa gtgttggtgg catccaccca agggtcttct     1980

cccccaaccc cagccgtgca ggccacctcc tccggggcca tcacccttcc tcccaagcct     2040

gcgcccaccg gcacatcctg cgaaccaaag atcgtcatca acacggtccc ccagctccac     2100

tcggagaaaa ccatgtatct taagtccagc gacaaccgc                            2139


<210>  4276
<211>  1875
<212>  DNA
<213>  Homo Sapiens

<400>  4276
cgcgtccccc gctcggtgcc cagaacctcg cttccaatct ctgaggctga ctcctgtctc       60

acccggttcg cagtccctca cacatacaat tactctgttc tccttgtgga tcctgcctcc      120

cacacacttt atgttggcgc ccgggacacc atcttcgctt tatccctgcc cttctcaggg      180

gagagacccc gcaggattga ctggatggtt cctgaggctc acagacagaa ctgtaggaag      240

aaaggcaaga aagaggacga atgtcacaat tttgtccaga ttctcgccat tgccaatgcc      300

tctcacctcc tcacttgtgg caccttcgct tttgatccga agtgcggggt tattgatgtg      360

tccaggttcc agcaggttga aagacttgag agtggccggg ggaaatgtcc ttttgagcca      420

gctcagcggt cagcagctgt aatggctggg ggggtcctct atgctgccac tgtgaaaaac      480

tacctgggga cggagccaat tatcaccaga gcagtgggtc gtgccgagga ctggattcgg      540

acagatacct tgccttcctg gctgaacgcc ccagcctttg tcgcagccgt ggccttgagc      600

ccagccgaat ggggggatga agatggagac gacgaaatct acttcttctt tacggagact      660

tcccgagcat ttgactcata cgagcgcatt aaagtcccac gggtggcccg tgtgtgtgcg      720

ggggacctcg ggggccggaa gaccctccag cagagatgga cgacgttttt gaaagctgac      780

ctgctctgtc cagggcctga gcatggccgg gcctccagtg tcctgcagga tgttgctgtg      840

cttcgacctg agcttggggc agggactccc atcttttatg gcatcttttc ttcccagtgg      900

gagggggcta ctatctctgc tgtctgtgcc ttccgaccac aagacattcg gacagtgctg      960

aatggtccct tcagagaact aaaacatgac tgcaacagag gactgcctgt cgtggacaat     1020

gatgtgcccc agcccagacc tggagagtgc atcaccaaca acatgaagct ccggcacttt     1080

ggctcatctc tctccctgcc tgaccgcgta ctcaccttca tccgggacca cccactcatg     1140

gacaggccag tgtttccagc tgatggccac cccctgctgg tcactacaga tacagcctat     1200

ctcagagtcg tggcccacag ggtgaccagc ctctcaggga aagagtatga tgtgctctac     1260

ctggggacag aggatggaca cctccaccga gcagtgcgga tcggagctca gctcagcgtt     1320

cttgaagatc tggccttatt cccagagcca cagccagttg agaacatgaa attgtaccac     1380

agctggctcc tggttggctc ccgtactgag gtgacacaag tgaatacaac caactgtggc     1440

cgtctccaga gctgctcaga gtgcatcctg gcccaggacc cagtctgtgc ctggagcttc     1500

cggctggatg agtgtgtggc ccatgccggg gagcaccgag ggttggtcca agacatagag     1560

tcagcagatg tctcctcttt gtgtcctaaa gagcctggag aacgtccagt agtgtttgaa     1620

gttcccgtgg ctacagctgc gcatgtggtc ttgccatgtt ctccaagctc agcatgggca     1680

tcctgtgtgt ggcaccagcc cagtggagtg actgcactca ccccccggcg ggatggactg     1740

gaggtggtgg tgaccccagg ggccatgggc gcttatgcct gtgaatgtca ggagggtggg     1800

gcagcccatg tggtagcagc ttacagcttg gtatggggca gccagcgaga tgctccgagc     1860

cgggcccaca cagtg                                                      1875


<210>  4277
<211>  1989
<212>  DNA
<213>  Homo Sapiens

<400>  4277
gtcccaggac cctcactgcg gagaccgtct agagaactag atgccacccc tcggatgacc       60

ataccctatg aagagctctc tgggacccgg cacttcaagg gccaagccca gaactactca      120

acactgctgc tggaggaggc ctcagcaagg ctgctggtgg gagcccgagg tgccctgttc      180

tctctcagtg ccaacgacat aggagatggg gctcacaaag agatccactg ggaagcctcc      240

ccagagatgc aaagcaaatg tcatcaaaaa gggaaaaaca accagacgga gtgctttaac      300

catgtgcggt tcctgcagcg gctcaattct acccacctct atgcatgtgg gactcacgcc      360

ttccagcccc tctgtgcagc cattgatgct gaggccttca ccttgccaac cagcttcgag      420

gaggggaagg agaagtgtcc ttatgaccca gcccgtggct tcacaggcct catcattgat      480

ggaggcctct acacagccac taggtatgaa ttccggagca ttcctgacat ccgccggagc      540

cgccacccac actccctgag aactgaggag acaccaatgc attggctcaa tgatgcggag      600

tttgtgttct ccgtcctcgt gcgggagagc aaggccagtg cagtgggtga tgatgacaag      660

gtgtactact tcttcacgga gcgtgccact gaggagggct ctggcagctt cactcagagc      720

cgcagcagtc accgtgtggc ccgtgtggct cgtgtctgca agggagacct gggagggaag      780

aagatcctgc agaagaagtg gacttccttc ctgaaagccc gtctcatctg ccacattcca      840

ctgtatgaga cactgcgtgg ggtctgcagc ctggatgctg aaacctcaag ccgtacacac      900

ttctatgcag ccttcacgct gagcacacag tggaagaccc tggaggcctc agccatctgc      960

cgctatgacc tggcagagat ccaggctgtc tttgcaggac cctatatgga ataccaggat     1020

ggttcccggc gctggggtcg ctatgagggt ggggtgcctg agccccggcc tggctcgtgt     1080

atcacagatt cattgcgcag ccaaggctac aattcatccc aagacttgcc atccctggtc     1140

ctggactttg taaagttgca cccactgatg gctcggcccg ttgtgcccac acgtggacgg     1200

cccctgctgc tcaagcgcaa catacgctac acacacctta cagggacacc tgtcaccacg     1260

cctgctggac ctacctatga cctgctcttt ctgggcacag ctgatggctg gatccacaag     1320

gccgtagtcc tgggctctgg gatgcacatt attgaagaga cacaagtgtt cagggagtcc     1380

cagtctgtgg aaaatctagt catctctcta ttgcagcaca gcctctatgt gggggctcct     1440

agcggagtca tccagctacc actctccagc tgctcccgct accgatcctg ctatgactgc     1500

atcttggccc gagaccccta ctgtggctgg gaccctggca cccatgcctg cgcagcagcc     1560

accaccatag ccaacaggtc ccagggaagc aggacagcac tgatacagga catagagaga     1620

ggaaatcgag gctgtgagag cagcagggat acagggccac caccaccact gaagacccgc     1680

tctgtgctcc ggggtgatga tgtcctcctg ccctgtgacc agccatccaa cctggcccgg     1740

gccttgtggc tactcaatgg gagcatgggc ctgagcgatg ggcagggtgg ctaccgtgtg     1800

ggcgtggacg ggctgctggt tacagatgca cagcctgagc acagtggcaa ctatggctgc     1860

tatgccgagg aaaatggcct ccgcaccctg ctggcctcct atagtctcac agtccggcca     1920

gccactcctg ccccagctcc aaaagcccct gccacacctg gggcacagct ggcacctgat     1980

gtgagactg                                                             1989


<210>  4278
<211>  3108
<212>  DNA
<213>  Homo Sapiens

<400>  4278
atgccctgtg gcttcagtcc gtctcctgtt gcccaccacc tcgtccctgg gccgcctgat       60

accccagccc aacagctaag gtgtggatgg acagtagggg gctggcttct ctcactggtc      120

aggggtcttc tcccctgtct gcctcccgga gctaggactg cagaggggcc tatcatggtg      180

cttgcaggcc ccctggctgt ctcgctgttg ctgcccagcc tcacactgct ggtgtcccac      240

ctctccagct cccaggatgt ctccagtgag cccagcagtg agcagcagct gtgcgccctt      300

agcaagcacc ccaccgtggc ctttgaagac ctgcagccgt gggtctctaa cttcacctac      360

cctggagccc gggatttctc ccagctggct ttggacccct ccgggaacca gctcatcgtg      420

ggagccagga actacctctt cagactcagc cttgccaatg tctctcttct tcaggccaca      480

gagtgggcct ccagtgagga cacgcgccgc tcctgccaaa gcaaagggaa gactgaggag      540

gagtgtcaga actacgtgcg agtcctgatc gtcgccggcc ggaaggtgtt catgtgtgga      600

accaatgcct tttcccccat gtgcaccagc agacaggtgg ggaacctcag ccggactatt      660

gagaagatca atggtgtggc ccgctgcccc tatgacccac gccacaactc cacagctgtc      720

atctcctccc agggggagct ctatgcagcc acggtcatcg acttctcagg tcgggaccct      780

gccatctacc gcagcctggg cagtgggcca ccgcttcgca ctgcccaata taactccaag      840

tggcttaatg agccaaactt cgtggcagcc tatgatattg ggctgtttgc atacttcttc      900

ctgcgggaga acgcagtgga gcacgactgt ggacgcaccg tgtactctcg cgtggcccgc      960

gtgtgcaaga atgacgtggg gggccgattc ctgctggagg acacatggac cacattcatg     1020

aaggcccggc tcaactgctc ccgcccgggc gaggtcccct tctactataa cgagctgcag     1080

agtgccttcc acttgccgga gcaggacctc atctatggag ttttcacaac caacgtaaac     1140

agcattgcgg cttctgctgt ctgcgccttc aacctcagtg ctatctccca ggctttcaat     1200

ggcccatttc gctaccagga gaaccccagg gctgcctggc tccccatagc caaccccatc     1260

cccaatttcc agtgtggcac cctgcctgag accggtccca acgagaacct gacggagcgc     1320

agcctgcagg acgcgcagcg cctcttcctg atgagcgagg ccgtgcagcc ggtgacaccc     1380

gagccctgtg tcacccagga cagcgtgcgc ttctcacacc tcgtggtgga cctggtgcag     1440

gctaaagaca cgctctacca tgtactctac attggcaccg agtcgggcac catcctgaag     1500

gcgctgtcca cggcgagccg cagcctccac ggctgctacc tggaggagct gcacgtgctg     1560

ccccccgggc gccgcgagcc cctgcgcagc ctgcgcatcc tgcacagcgc ccgcgcgctc     1620

ttcgtggggc tgagagacgg cgtcctgcgg gtcccactgg agaggtgcgc cgcctaccgc     1680

agccaggggg catgcctggg ggcccgggac ccgtactgtg gctgggacgg gaagcagcaa     1740

cgttgcagca cactcgagga cagctccaac atgagcctct ggacccagaa catcaccgcc     1800

tgtcctgtgc ggaatgtgac acgggatggg ggcttcggcc catggtcacc atggcaacca     1860

tgtgagcact tggatgggga caactcaggc tcttgcctgt gtcgagctcg atcctgtgat     1920

tcccctcgac cccgctgtgg gggccttgac tgcctggggc cagccatcca catcgccaac     1980

tgctccagga atggggcgtg gaccccgtgg tcatcgtggg cgctgtgcag cacgtcctgt     2040

ggcatcggct tccaggtccg ccagcgaagt tgcagcaacc ctgctccccg ccacgggggc     2100

cgcatctgcg tgggcaagag ccgggaggaa cggttctgta atgagaacac gccttgcccg     2160

gtgcccatct tctgggcttc ctggggctcc tggagcaagt gcagcagcaa ctgtggaggg     2220

ggcatgcagt cgcggcgtcg ggcctgcgag aacggcaact cctgcctggg ctgcggcgtg     2280

gagttcaaga cgtgcaaccc cgagggctgc cccgaagtgc ggcgcaacac cccctggacg     2340

ccgtggctgc ccgtgaacgt gacgcagggc ggggcacggc aggagcagcg gttccgcttc     2400

acctgccgcg cgccccttgc agacccgcac ggcctgcagt tcggcaggag aaggaccgag     2460

acgaggacct gtcccgcgga cggctccggc tcctgcgaca ccgacgccct ggtggaggac     2520

ctcctgcgca gcgggagcac ctccccgcac acggtgagcg ggggctgggc cgcctggggc     2580

ccgtggtcgt cctgctcccg ggactgcgag ctgggcttcc gcgtccgcaa gagaacgtgc     2640

actaacccgg agccccgcaa cgggggcctg ccctgcgtgg gcgatgctgc cgagtaccag     2700

gactgcaacc cccaggcttg cccagttcgg ggtgcttggt cctgctggac ctcatggtct     2760

ccatgctcag cttcctgtgg tgggggtcac tatcaacgca cccgttcctg caccagcccc     2820

gcaccctccc caggtgagga catctgtctc gggctgcaca cggaggaggc actatgtgcc     2880

acacaggcct gcccagaagg ctggtcgccc tggtctgagt ggagtaagtg cactgacgac     2940

ggagcccaga gccgaagccg gcactgtgag gagctcctcc cagggtccag cgcctgtgct     3000

ggaaacagca gccagagccg cccctgcccc tacagcgaga ttcccgtcat cctgccagcc     3060

tccagcatgg aggaggccac cggctgtgca gggttcaatc tcatccac                  3108


<210>  4279
<211>  1893
<212>  DNA
<213>  Homo Sapiens

<400>  4279
ggtttcccag aagattctga gccaatcagt atttcgcatg gcaactatac aaaacagtat       60

ccggtgtttg tgggccacaa gccaggacgg aacaccacac agaggcacag gctggacatc      120

cagatgatta tgatcatgaa cggaaccctc tacattgctg ctagggacca tatttatact      180

gttgatatag acacatcaca cacggaagaa atttattgta gcaaaaaact gacatggaaa      240

tctagacagg ccgatgtaga cacatgcaga atgaagggaa aacataagga tgagtgccac      300

aactttatta aagttcttct aaagaaaaac gatgatgcat tgtttgtctg tggaactaat      360

gccttcaacc cttcctgcag aaactataag atggatacat tggaaccatt cggggatgaa      420

ttcagcggaa tggccagatg cccatatgat gccaaacatg ccaacgttgc actgtttgca      480

gatggaaaac tatactcagc cacagtgact gacttccttg ccattgacgc agtcatttac      540

cggagtcttg gagaaagccc taccctgcgg accgtcaagc acgattcaaa atggttgaaa      600

gaaccatact ttgttcaagc cgtggattac ggagattata tctacttctt cttcagggaa      660

atagcagtgg agtataacac catgggaaag gtagttttcc caagagtggc tcaggtttgt      720

aagaatgata tgggaggatc tcaaagagtc ctggagaaac agtggacgtc gttcctgaag      780

gcgcgcttga actgctcagt tcctggagac tctcattttt atttcaacat tctccaggca      840

gttacagatg tgattcgtat caacgggcgt gatgttgtcc tggcaacgtt ttctacacct      900

tataacagca tccctgggtc tgcagtctgt gcctatgaca tgcttgacat tgccagtgtt      960

tttactggga gattcaagga acagaagtct cctgattcca cctggacacc agttcctgat     1020

gaacgagttc ctaagcccag gccaggttgc tgtgctggct catcctcctt agaaagatat     1080

gcaacctcca atgagttccc tgatgatacc ctgaacttca tcaagacgca cccgctcatg     1140

gatgaggcag tgccctccat cttcaacagg ccatggttcc tgagaacaat ggtcagatac     1200

cgccttacca aaattgcagt ggacacagct gctgggccat atcagaatca cactgtggtt     1260

tttctgggat cagagaaggg aatcatcttg aagtttttgg ccagaatagg aaatagtggt     1320

tttctaaatg acagcctttt cctggaggag atgagtgttt acaactctga aaaatgcagc     1380

tatgatggag tcgaagacaa aaggatcatg ggcatgcagc tggacagagc aagcagctct     1440

ctgtatgttg cgttctctac ctgtgtgata aaggttcccc ttggccggtg tgaacgacat     1500

gggaagtgta aaaaaacctg tattgcctcc agagacccat attgtggatg gataaaggaa     1560

ggtggtgcct gcagccattt atcacccaac agcagactga cttttgagca ggacatagag     1620

cgtggcaata cagatggtct gggggactgt cacaattcct ttgtggcact gaatgggcat     1680

tccagttccc tcttgcccag cacaaccaca tcagattcga cggctcaaga ggggtatgag     1740

tctaggggag gaatgctgga ctggaagcat ctgcttgact cacctgacag cacagaccct     1800

ttgggggcag tgtcttccca taatcaccaa gacaagaagg gagtgattcg ggaaagttac     1860

ctcaaaggcc acgaccagct ggttcccgtc acc                                  1893


<210>  4280
<211>  1734
<212>  DNA
<213>  Homo Sapiens

<400>  4280
ctctttcctg aggagccgcc gccgcttagc gtggccccca gggactacct gaaccactat       60

cccgtgtttg tgggcagcgg gcccggacgc ctgacccccg cagaaggtgc tgacgacctc      120

aacatccagc gagtcctgcg ggtcaacagg acgctgttca ttggggacag ggacaacctc      180

taccgcgtag agctggagcc ccccacgtcc acggagctgc ggtaccagag gaagctgacc      240

tggagatcta accccagcga cataaacgtg tgtcggatga agggcaaaca ggagggcgag      300

tgtcgaaact tcgtaaaggt gctgctcctt cgggacgagt ccacgctctt tgtgtgcggt      360

tccaacgcct tcaacccggt gtgcgccaac tacagcatag acaccctgca gcccgtcgga      420

gacaacatca gcggtatggc ccgctgcccg tacgacccca agcacgccaa tgttgccctc      480

ttctctgacg ggatgctctt cacagctact gttaccgact tcctagccat tgatgctgtc      540

atctaccgca gcctcgggga caggcccacc ctgcgcaccg tgaaacatga ctccaagtgg      600

ttcaaagagc cttactttgt ccatgcggtg gagtggggca gccatgtcta cttcttcttc      660

cgggagattg cgatggagtt taactacctg gagaaggtgg tggtgtcccg cgtggcccga      720

gtgtgcaaga acgacgtggg aggctccccc cgcgtgctgg agaagcagtg gacgtccttc      780

ctgaaggcgc ggctcaactg ctctgtaccc ggagactccc atttctactt caacgtgctg      840

caggctgtca cgggcgtggt cagcctcggg ggccggcccg tggtcctggc cgttttttcc      900

acgcccagca acagcatccc tggctcggct gtctgcgcct ttgacctgac acaggtggca      960

gctgtgtttg aaggccgctt ccgagagcag aagtcccccg agtccatctg gacgccggtg     1020

ccggaggatc aggtgcctcg accccggccc gggtgctgcg cagcccccgg gatgcagtac     1080

aatgcctcca gcgccttgcc ggatgacatc ctcaactttg tcaagaccca ccctctgatg     1140

gacgaggcgg tgccctcgct gggccatgcg ccctggatcc tgcggaccct gatgaggcac     1200

cagctgactc gagtggctgt ggacgtggga gccggcccct ggggcaacca gaccgttgtc     1260

ttcctgggtt ctgaggcggg gacggtcctc aagttcctcg tccggcccaa tgccagcacc     1320

tcagggacgt ctgggctcag tgtcttcctg gaggagtttg agacctaccg gccggacagg     1380

tgtggacggc ccggcggtgg cgagacaggg cagcggctgc tgagcttgga gctggacgca     1440

gcttcggggg gcctgctggc tgccttcccc cgctgcgtgg tccgagtgcc tgtggctcgc     1500

tgccagcagt actcggggtg tatgaagaac tgtatcggca gtcaggaccc ctactgcggg     1560

tgggcccccg acggctcctg catcttcctc agcccgggca ccagagccgc ctttgagcag     1620

gacgtgtccg gggccagcac ctcaggctta ggggactgca caggactcct gcgggccagc     1680

ctctccgagg accgcgcggg gctggtgtcg gtgaacctgc tggtaacgtc gtcg           1734


<210>  4281
<211>  1539
<212>  DNA
<213>  Homo Sapiens

<400>  4281
gcctttcccc aggaccccct ccctctgttg atctctgacc ttcaaggtac ttccccatta       60

tcctggtttc ggggcctgga ggatgatgct gtggctgcag aacttgggct ggactttcag      120

agattcctga ccttgaaccg gaccttgcta gtggctgccc gggatcacgt tttctccttc      180

gatcttcaag ccgaagaaga aggggagggg ctggtgccca acaagtatct aacatggaga      240

agccaagatg tggagaactg tgctgtacgg ggaaagctga cggatgagtg ctacaactat      300

attcgtgttc ttgttccctg ggactcccag acgctccttg cctgtggaac gaactcattc      360

agccctgtgt gccgcagcta tgggataact tcgctgcagc aggagggtga ggaactgagt      420

gggcaggctc gatgcccctt tgatgccacc cagtccaacg tggccatctt tgcagagggc      480

agcctgtact cagccacagc tgcggatttc caggccagtg atgctgtagt ttacagaagc      540

cttgggcccc agcccccact ccgctccgcc aagtatgact ccaagtggct ccgagagcca      600

cactttgtcc aggccttgga gcatggagac catgtctact tcttcttccg cgaggtctct      660

gtggaggatg ctcggctggg gagggtgcag ttctcccgcg tagcccgagt atgtaaacgt      720

gacatgggcg gctcgcctcg ggccttggac cgccactgga catccttcct gaagcttcgg      780

ctcaactgct ctgtccctgg ggactctact ttctattttg atgttttaca ggccttgact      840

gggcctgtga acctgcatgg ccgctctgct ctctttgggg tcttcaccac ccagaccaat      900

agcatccctg gctctgccgt ctgcgccttc tacctggatg agattgagcg tgggtttgag      960

ggcaagttca aggagcagag gagtctggat ggggcctgga ctcctgtgtc tgaggacaga     1020

gttccctcac ccaggccagg atcctgccct gctcactcga gtcccctcgg gaggtccctc     1080

caggtactcc gggggtcccg ggaagcacct cctgtacctg ggccggcccg agggctaccg     1140

gggccgcgcc ctgaaaaggg tggacgtcga gaagccccag ttgtccctga agcctcccct     1200

cgtcgggccc tcctcccgcc aggccgtccc gaacggcggc cgtttcaact tttaaaggga     1260

gcggtccacg gcctccagcg tggggagcgc ccgagtcctc tcggccacga gctggacgct     1320

cttcaggacg tttcaccgcc ccctcgcccc gcacctccag ccttcccgac tcgcagagtc     1380

tcccgaggcc ccttttcgcc tcgggtttat ttattgactg tctttccccc tgtcctcgac     1440

agaagagtgg gaggtgagaa gcccgtctcc tcagtgagcc agcatttcag ggggagctgg     1500

cggactccca ctccccgctc ccttccagcc aagctgcct                            1539


<210>  4282
<211>  1812
<212>  DNA
<213>  Homo Sapiens

<400>  4282
cagggccacc taaggagcgg accccgcatc ttcgccgtct ggaaaggcca tgtagggcag       60

gaccgggtgg actttggcca gactgagccg cacacggtgc ttttccacga gccaggcagc      120

tcctctgtgt gggtgggagg acgtggcaag gtctacctct ttgacttccc cgagggcaag      180

aacgcatctg tgcgcacggt gaatatcggc tccacaaagg ggtcctgtct ggataagcgg      240

gactgcgaga actacatcac tctcctggag aggcggagtg aggggctgct ggcctgtggc      300

accaacgccc ggcaccccag ctgctggaac ctggtgaatg gcactgtggt gccacttggc      360

gagatgagag gctacgcccc cttcagcccg gacgagaact ccctggttct gtttgaaggg      420

gacgaggtgt attccaccat ccggaagcag gaatacaatg ggaagatccc tcggttccgc      480

cgcatccggg gcgagagtga gctgtacacc agtgatactg tcatgcagaa cccacagttc      540

atcaaagcca ccatcgtgca ccaagaccag gcttacgatg acaagatcta ctacttcttc      600

cgagaggaca atcctgacaa gaatcctgag gctcctctca atgtgtcccg tgtggcccag      660

ttgtgcaggg gggaccaggg tggggaaagt tcactgtcag tctccaagtg gaacactttt      720

ctgaaagcca tgctggtatg cagtgatgct gccaccaaca agaacttcaa caggctgcaa      780

gacgtcttcc tgctccctga ccccagcggc cagtggaggg acaccagggt ctatggtgtt      840

ttctccaacc cctggaacta ctcagccgtc tgtgtgtatt ccctcggtga cattgacaag      900

gtcttccgta cctcctcact caagggctac cactcaagcc ttcccaaccc gcggcctggc      960

aagtgcctcc cagaccagca gccgataccc acagagacct tccaggtggc tgaccgtcac     1020

ccagaggtgg cgcagagggt ggagcccatg gggcctctga agacgccatt gttccactct     1080

aaataccact accagaaagt ggccgtccac cgcatgcaag ccagccacgg ggagaccttt     1140

catgtgcttt acctaactac agacaggggc actatccaca aggtggtgga accgggggag     1200

caggagcaca gcttcgcctt caacatcatg gagatccagc ccttccgccg cgcggctgcc     1260

atccagacca tgtcgctgga tgctgagcgg aggaagctgt atgtgagctc ccagtgggag     1320

gtgagccagg tgcccctgga cctgtgtgag gtctatggcg ggggctgcca cggttgcctc     1380

atgtcccgag acccctactg cggctgggac caaggccgct gcatctccat ctacagctcc     1440

gaacggtcag tgctgcaatc cattaatcca gccgagccac acaaggagtg tcccaacccc     1500

aaaccagaca aggccccact gcagaaggtt tccctggccc caaactctcg ctactacctg     1560

agctgcccca tggaatcccg ccacgccacc tactcatggc gccacaagga gaacgtggag     1620

cagagctgcg aacctggtca ccagagcccc aactgcatcc tgttcatcga gaacctcacg     1680

gcgcagcagt acggccacta cttctgcgag gcccaggagg gctcctactt ccgcgaggct     1740

cagcactggc agctgctgcc cgaggacggc atcatggccg agcacctgct gggtcatgcc     1800

tgtgccctgg cc                                                         1812


<210>  4283
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4283
atgacagtag gagagaaggt cttctccagc aatgggcagt ccatcacttt tgatgccatt       60

caggaggcat gtgccagagc aggcggccgc attgctgtcc caaggaatcc agaggaaaat      120

gaggccattg caagcttcgt gaagaagtac aacacatatg cctatgtagg cctgactgag      180

ggtcccagcc ctggagactt ccgctactca gacgggaccc ctgtaaacta caccaactgg      240

taccgagggg agcccgcagg tcggggaaaa gagcagtgtg tggagatgta cacagatggg      300

cagtggaatg acaggaactg cctgtactcc cgactgacca tctgtgagtt c               351


<210>  4284
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  4284
gaagtgaagg acgtttgtgt tggaagccct ggtatccccg gcactcctgg atcccacggc       60

ctgccaggca gggacgggag agatggtgtc aaaggagacc ctggccctcc aggccccatg      120

ggtccgcctg gagaaacacc atgtcctcct gggaataatg ggctgcctgg agcccctggt      180

gtccctggag agcgtggaga gaagggggag gctggcgaga gaggccctcc agggcttcca      240

gctcatctag atgaggagct ccaagccaca ctccacgact tcagacatca aatcctgcag      300

acaaggggag ccctcagtct gcagggctcc ataatgacag taggagagaa ggtcttctcc      360

agcaatgggc agtccatcac ttttgatgcc attcaggagg catgtgccag agcaggcggc      420

cgcattgctg tcccaaggaa tccagaggaa aatgaggcca ttgcaagctt cgtgaagaag      480

tacaacacat atgcctatgt aggcctgact gagggtccca gccctggaga cttccgctac      540

tcagacggga cccctgtaaa ctacaccaac tggtaccgag gggagcccgc aggtcgggga      600

aaagagcagt gtgtggagat gtacacagat gggcagtgga atgacaggaa ctgcctgtac      660

tcccgactga ccatctgtga gttc                                             684


<210>  4285
<211>  1065
<212>  DNA
<213>  Homo Sapiens

<400>  4285
gcaggaatga agacctactc ccacagaaca atgcccagtg cttgcaccct ggtcatgtgt       60

agctcagtgg agagtggcct gcctggtcgc gatggacggg atgggagaga gggccctcgg      120

ggcgagaagg gggacccagg tttgccagga gctgcagggc aagcagggat gcctggacaa      180

gctggcccag ttgggcccaa aggggacaat ggctctgttg gagaacctgg accaaaggga      240

gacactgggc caagtggacc tccaggacct cccggtgtgc ctggtccagc tggaagagaa      300

ggtcccctgg ggaagcaggg gaacatagga cctcagggca agccaggccc aaaaggagaa      360

gctgggccca aaggagaagt aggtgcccca ggcatgcagg gctcggcagg ggcaagaggc      420

ctcgcaggcc ctaagggaga gcgaggtgtc cctggtgagc gtggagtccc tggaaacaca      480

ggggcagcag ggtctgctgg agccatgggt ccccagggaa gtccaggtgc caggggaccc      540

ccgggattga agggggacaa aggcattcct ggagacaaag gagcaaaggg agaaagtggg      600

cttccagatg ttgcttctct gaggcagcag gttgaggcct tacagggaca agtacagcac      660

ctccaggctg ctttctctca gtataagaaa gttgagctct tcccaaatgg ccaaagtgtc      720

ggggagaaga ttttcaagac agcaggcttt gtaaaaccat ttacggaggc acagctgctg      780

tgcacacagg ctggtggaca gttggcctct ccacgctctg ccgctgagaa tgccgccttg      840

caacagctgg tcgtagctaa gaacgaggct gctttcctga gcatgactga ttccaagaca      900

gagggcaagt tcacctaccc cacaggagag tccctggtct attccaactg ggccccaggg      960

aagcccaacg atgatggcgg gtcagaggac tgtgtggaga tcttcaccaa tggcaagtgg     1020

aatgacaggg cttgtggaga aaagcgtctt gtggtctgcg agttc                     1065


<210>  4286
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  4286
atgccaggtg tctgtgatag ggcccctgac ttcctctccc cgtctgaaga ccaggtgctg       60

aggcctgcct tgggcagctc agtggctctg aactgcacgg cttgggtagt ctctgggccc      120

cactgctccc tgccttcagt ccagtggctg aaagacgggc ttccattggg aattgggggc      180

cactacagcc tccacgagta ctcctgggtc aaggccaacc tgtcagaggt gcttgtgtcc      240

agtgtcctgg gggtcaacgt gaccagcact gaagtctatg gggccttcac ctgctccatc      300

cagaacatca gcttctcctc cttcactctt cagagagctg gccctacaag ccac            354


<210>  4287
<211>  1602
<212>  DNA
<213>  Homo Sapiens

<400>  4287
atggatggga gattctggat acgagtgcag gagtcagtga tggtgccgga gggcctgtgc       60

atctctgtgc cctgctcttt ctcctacccc cgacaagact ggacagggtc taccccagct      120

tatggctact ggttcaaagc agtgactgag acaaccaagg gtgctcctgt ggccacaaac      180

caccagagtc gagaggtgga aatgagcacc cggggccgat tccagctcac tggggatccc      240

gccaagggga actgctcctt ggtgatcaga gacgcgcaga tgcaggatga gtcacagtac      300

ttctttcggg tggagagagg aagctatgtg agatataatt tcatgaacga tgggttcttt      360

ctaaaagtaa cagccctgac tcagaagcct gatgtctaca tccccgagac cctggagccc      420

gggcagccgg tgacggtcat ctgtgtgttt aactgggcct ttgaggaatg tccaccccct      480

tctttctcct ggacgggggc tgccctctcc tcccaaggaa ccaaaccaac gacctcccac      540

ttctcagtgc tcagcttcac gcccagaccc caggaccaca acaccgacct cacctgccat      600

gtggacttct ccagaaaggg tgtgagcgta cagaggaccg tccgactccg tgtggcctat      660

gcccccagag accttgttat cagcatttca cgtgacaaca cgccagccct ggagccccag      720

ccccagggaa atgtcccata cctggaagcc caaaaaggcc agttcctgcg gctcctctgt      780

gctgctgaca gccagccccc tgccacactg agctgggtcc tgcagaacag agtcctctcc      840

tcgtcccatc cctggggccc tagacccctg gggctggagc tgcccggggt gaaggctggg      900

gattcagggc gctacacctg ccgagcggag aacaggcttg gctcccagca gcgagccctg      960

gacctctctg tgcagtatcc tccagagaac ctgagagtga tggtttccca agcaaacagg     1020

acagtcctgg aaaaccttgg gaacggcacg tctctcccag tactggaggg ccaaagcctg     1080

tgcctggtct gtgtcacaca cagcagcccc ccagccaggc tgagctggac ccagagggga     1140

caggttctga gcccctccca gccctcagac cccggggtcc tggagctgcc tcgggttcaa     1200

gtggagcacg aaggagagtt cacctgccac gctcggcacc cactgggctc ccagcacgtc     1260

tctctcagcc tctccgtgca ctactccccg aagctgctgg gcccctcctg ctcctgggag     1320

gctgagggtc tgcactgcag ctgctcctcc caggccagcc cggccccctc tctgcgctgg     1380

tggcttgggg aggagctgct ggaggggaac agcagccagg actccttcga ggtcaccccc     1440

agctcagccg ggccctgggc caacagctcc ctgagcctcc atggagggct cagctccggc     1500

ctcaggctcc gctgtgaggc ctggaacgtc catggggccc agagtggatc catcctgcag     1560

ctgccagata agaagggact catctcaacg gcattctcca ac                        1602


<210>  4288
<211>  1602
<212>  DNA
<213>  Homo Sapiens

<400>  4288
ctgaacaagg atcccagtta cagtcttcaa gtgcagaggc aggtgccggt gccggagggc       60

ctgtgtgtca tcgtgtcttg caacctctcc tacccccggg atggctggga cgagtctact      120

gctgcttatg gctactggtt caaaggacgg accagcccaa agacgggtgc tcctgtggcc      180

actaacaacc agagtcgaga ggtggaaatg agcacccggg accgattcca gctcactggg      240

gatcccggca aagggagctg ctccttggtg atcagagacg cgcagaggga ggatgaggca      300

tggtacttct ttcgggtgga gagaggaagc cgtgtgagac atagtttcct gagcaatgcg      360

ttctttctaa aagtaacagc cctgactaag aagcctgatg tctacatccc cgagaccctg      420

gagcccgggc agccggtgac ggtcatctgt gtgtttaact gggctttcaa gaaatgtcca      480

gccccttctt tctcctggac gggggctgcc ctctccccta gaagaaccag accaagcacc      540

tcccacttct cagtgctcag cttcacgccc agcccccagg accacgacac cgacctcacc      600

tgccatgtgg acttctccag aaagggtgtg agcgcacaga ggaccgtccg actccgtgtg      660

gcctatgccc ccaaagacct tattatcagc atttcacatg acaacacgtc agccctggaa      720

ctccagggaa acgtcatata tctggaagtt cagaaaggcc agttcctgcg gctcctctgt      780

gctgctgaca gccagccccc tgccacgctg agctgggtcc tgcaggacag agtcctctcc      840

tcgtcccacc cctggggccc cagaaccctg gggctggagc tgcgtggggt aagggccggg      900

gattcagggc gctacacctg ccgagcggag aacaggcttg gctcccagca gcaagccctg      960

gacctctctg tgcagtatcc tccagagaac ctgagagtga tggtttccca agcaaacagg     1020

acagtcctgg aaaacctcgg gaacggcaca tccctcccgg tcctggaggg ccaaagcctg     1080

cgcctggtct gtgtcaccca cagcagcccc ccagccaggc tgagctggac ccggtgggga     1140

cagaccgtgg gcccctccca gccctcagac cccggggtcc tggagctgcc acccattcaa     1200

atggagcacg aaggagagtt cacctgccac gctcagcacc ctctgggctc ccagcacgtc     1260

tctctcagcc tctccgtgca ctaccctcca cagctgctgg gcccctcctg ctcctgggag     1320

gctgagggtc tgcactgcag ctgctcctcc caggccagcc cggccccctc tctgcgctgg     1380

tggcttgggg aggagctgct ggaggggaac agcagtcagg gctccttcga ggtcaccccc     1440

agctcagccg ggccctgggc caacagctcc ctgagcctcc atggagggct cagctccggc     1500

ctcaggctcc gctgtaaggc ctggaacgtc cacggggccc agagtggctc tgtcttccag     1560

ctgctaccag ggaagctgga gcatggggga ggacttggcc tg                        1602


<210>  4289
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  4289
aaggaacaga aggattacct gctgacaatg cagaagtccg tgacggtgca ggagggcctg       60

tgtgtctctg tgctttgctc cttctcctac ccccaaaatg gctggactgc ctccgatcca      120

gttcatggct actggttccg ggcaggggac catgtaagcc ggaacattcc agtggccaca      180

aacaacccag ctcgagcagt gcaggaggag actcgggacc gattccacct ccttggggac      240

ccacagaaca aggattgtac cctgagcatc agagacacca gagagagtga tgcagggaca      300

tacgtctttt gtgtagagag aggaaatatg aaatggaatt ataaatatga ccagctctct      360

gtgaatgtga cagcgtccca ggacctactg tcaagataca ggctggaggt gccagagtcg      420

gtgactgtgc aggagggtct gtgtgtctct gtgccctgca gtgtccttta cccccattac      480

aactggactg cctctagccc tgtttatgga tcctggttca aggaaggggc cgatatacca      540

tgggatattc cagtggccac aaacacccca agtggaaaag tgcaagagga tacccacggt      600

cgattcctcc tccttgggga cccacagacc aacaactgct ccctgagcat cagagatgcc      660

aggaaggggg attcagggaa gtactacttc caggtggaga gaggaagcag gaaatggaac      720

tacatatatg acaagctctc tgtgcatgtg acagccctga ctcacatgcc caccttctcc      780

atcccgggga ccctggagtc tggccacccc aggaacctga cctgctctgt gccctgggcc      840

tgtgaacagg ggacgccccc cacgatcacc tggatggggg cctccgtgtc ctccctggac      900

cccactatca ctcgctcctc gatgctcagc ctcatcccac agccccagga ccatggcacc      960

agcctcacct gtcaggtgac cttgcctggg gccggcgtga ccatgaccag ggctgtccga     1020

ctcaacatat cctatcctcc tcagaacttg accatgactg tcttccaagg agatggcaca     1080

gcatccacaa ccttgaggaa tggctcggcc ctttcagtcc tggagggcca gtccctgcac     1140

cttgtctgtg ctgtcgacag caatccccct gccaggctga gctggacctg ggggagcctg     1200

accctgagcc cctcacagtc ctcgaacctt ggggtgctgg agctgcctcg agtgcatgtg     1260

aaggatgaag gggaattcac ctgccgagct cagaaccctc taggctccca gcacatttcc     1320

ctgagcctct ccctgcaaaa cgagtacaca ggcaaaatga ggcctatatc aggagtgacg     1380

ctaggggca                                                             1389


<210>  4290
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  4290
gagaaacctg tatacgaatt acaggtgcag aagtcagtga cagttcaaga aggtttgtgt       60

gttctagtgc catgctcctt cagctacccc tggaggtcct ggtattcatc tccacccttg      120

tacgtttact ggttccgtga tggtgaaatc ccttattacg cggaggtcgt agcaacgaat      180

aaccctgaca gacgtgttaa gccggagacg caaggtaggt tcaggctgct tggagatgtt      240

caaaagaaga actgtagcct ttccattggt gacgccagaa tggaggacac aggctcctac      300

ttctttagag tcgaaagagg ccgtgacgta aagtattctt accaacagaa caaattgaat      360

ttagaagtaa cggctctgat cgaaaaaccc gacattcact ttttggagcc cttagaaagc      420

ggaagaccaa ccagactatc ctgcagcctt ccaggttcct gtgaagccgg gccaccacta      480

acattttcat ggactggcaa tgcccttagt cctttggacc cagagactac tagaagtagt      540

gaactaacac ttacccctag gcccgaggat cacggaacta accttacttg ccaagtaaag      600

agacaggggg cacaagtgac aacagagaga accgtacaac taaatgtgag ctacgctccc      660

cagaaccttg ctatcagcat cttctttagg aatgggacag ggacagccct aagaatactt      720

tctaatggca tgagcgttcc gatccaggag ggacaatctt tgttccttgc gtgcacagtc      780

gactccaatc ctccggcctc actatcttgg tttcgtgaag gaaaggccct gaatcctagt      840

caaacttcaa tgtctggtac cctagagctt cccaacatcg gtgcgaggga aggaggggaa      900

ttcacatgcc gtgtacagca tcccctaggt agtcagcatc tatcattcat tctatctgta      960

cagcgtagtt cctcttcatg tatctgcgtt accgagaaac aacagggcag ttggccgctt     1020

gtgttg                                                                1026


<210>  4291
<211>  732
<212>  DNA
<213>  Homo Sapiens

<400>  4291
tttgtaagga caaaaattga taccacggag aacttgctaa acaccgaagt gcatagcagt       60

ccagcccaac gttggtccat gcaagttcct cctgaagttt cagctgaagc cggtgatgcc      120

gcggtccttc catgtacctt cacacaccct cacagacact acgatggccc tcttacagcc      180

atttggaggg caggagaacc gtatgcggga ccccaggtgt ttcgttgcgc ggctgccaga      240

gggtccgaac tttgtcaaac ggcactgagt ctgcacggcc gtttccgtct gttgggcaac      300

ccgagaagga atgacttgtc attacgtgta gagagattgg ctctagccga cgacagaaga      360

tacttttgta gagtagagtt tgcaggcgat gttcacgacc gttacgagag cagacacgga      420

gtgaggcttc atgttaccgc cgccccaaga attgttaata tttcagtctt gccctcccca      480

gctcatgcgt tcagggcgct ttgtaccgcg gagggcgagc cccctccagc cctggcttgg      540

agcggcccag cattggggaa ctccctagct gccgtccgta gtccacgtga gggacacggt      600

cacttagtga cagccgaact acctgcgtta acccatgatg gaagatacac gtgcacagcc      660

gcaaatagct taggaagaag cgaggcatcc gtctatctgt tcagattcca cggggcgagt      720

ggagctagta ca                                                          732


<210>  4292
<211>  1254
<212>  DNA
<213>  Homo Sapiens

<400>  4292
aacaaagatc ctagttactc acttcaggtt caaagacaag ttccagttcc agaagggctg       60

tgtgttattg tgtcctgtaa tttatcctac ccgagagatg gatgggacga atctacggca      120

gcctacgggt attggttcaa aggacgtacc agccccaaga ctggagcgcc tgtcgcgaca      180

aataaccaat ccagagaggt ggctatgtcc acgagagata ggtttcaatt aactggtgat      240

ccggggaagg ggtcttgttc cctggtgatt agggacgctc aaagagagga cgaagcgtgg      300

tattttttta gagtggagag aggttctcgt gtaagacatt ccttcctatc aaacgccttc      360

tttctgaaag tgacggcgct gacgcaaaaa ccggacgtct atatacctga gacactggaa      420

ccaggacagc cggtaacagt gatctgcgta tttaactggg ctttcaaaaa atgtcctgcg      480

ccgtccttca gttggaccgg ggccgcttta agcccaagga gaacgagacc atcaacttcc      540

catttttctg tattgtcttt tacaccgtca ccacaagacc atgataccga tttaacgtgc      600

cacgttgact tcagcagaaa aggcgtctcc gctcaaagaa cggtgcgtct aagagtagct      660

agtctagagc tgcaaggcaa tgtcatctat ctagaggtcc aaaaggggca atttcttcgt      720

cttctatgtg cagctgacag ccagcctcct gctactctta gctgggtttt acaggataga      780

gtgctgagtt ctagccatcc gtgggggccg aggactctag gcttagaact acccggcgtt      840

aaggcaggtg actctggaag atatacttgc cgtgcagaga accgtctggg gagccaacag      900

agagcgctgg atctgtctgt acaatacccg cctgagaatt taagagtaat ggttagccag      960

gcaaatcgta ctgttttgga aaacctgagg aatggcacta gcttgcgtgt ccttgagggg     1020

cagagcctga gactagtttg tgtgacacat tcaagtccgc cggcacgtct gagctggacc     1080

tggggggaac aaacagtggg cccatctcaa cctagcgatc caggggtctt acagctaccg     1140

cgtgtccaaa tggaacacga gggtgagttt acttgtcatg ctcgtcaccc gctgggctcc     1200

caaagagtat ctttgtcatt cagcgttcac tgcaaatccg gcccaatgac aggc           1254


<210>  4293
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  4293
gagaagccag tgtacgagct gcaagtgcag aagtcggtga cggtgcagga gggcctgtgc       60

gtccttgtgc cctgctcctt ctcttacccc tggagatcct ggtattcctc tcccccactc      120

tacgtctact ggttccggga cggggagatc ccatactacg ctgaggttgt ggccacaaac      180

aacccagaca gaagagtgaa gccagagacc cagggccgat tccgcctcct tggggatgtc      240

cagaagaaga actgctccct gagcatcgga gatgccagaa tggaggacac gggaagctat      300

ttcttccgcg tggagagagg aagggatgta aaatatagct accaacagaa taagctgaac      360

ttggaggtga cagccctgat agagaaaccc gacatccact ttctggagcc tctggagtcc      420

ggccgcccca caaggctgag ctgcagcctt ccaggatcct gtgaagcggg accacctctc      480

acattctcct ggacggggaa tgccctcagc cccctggacc ccgagaccac ccgctcctcg      540

gagctcaccc tcacccccag gcccgaggac catggcacca acctcacctg tcagatgaaa      600

cgccaaggag ctcaggtgac cacggagaga actgtccagc tcaatgtctc ctatgcacca      660

cagaccatca ccatcttcag gaacggcata gccctagaga tcctgcaaaa cacctcatac      720

cttccggtcc tggagggcca ggctctgcgg ctgctctgtg atgctcccag caacccccct      780

gcacacctga gctggttcca gggctcccct gccctgaacg ccacccccat ctccaatacc      840

gggatcttgg agcttcgtcg agtaaggtct gcagaagaag gaggcttcac ctgccgcgct      900

cagcacccgc tgggcttcct gcaaattttt ctgaatctct cagtttactc cctcccacag      960

ttgctgggcc cctcctgctc ctgggaggct gagggtctgc actgcagatg ctcctttcga     1020

gcccggccgg ccccctccct gtgctggcgg cttgaggaga agccgctgga ggggaacagc     1080

agccagggct cattcaaggt caactccagc tcagctgggc cctgggccaa cagctccctg     1140

atcctccacg gggggctcag ctccgacctc aaagtcagct gcaaggcctg gaacatctat     1200

gggtcccaga gcggctctgt cctgctgctg caagggagat cgaaccttgg gacaggagtg     1260

gttcctgcag ccctt                                                      1275


<210>  4294
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  4294
caggagcgga gattccagct ggaggggcca gagtcactga cggtgcagga gggtctgtgc       60

gtcctcgtac cctgcagatt gcccactacc cttccagcct cgtactatgg ttatggctac      120

tggttcctgg aaggggctga tgttccagtg gccacaaacg acccagacga agaagtgcag      180

gaggagaccc ggggccgatt ccacctcctc tgggatccca gaaggaagaa ctgctccctg      240

agcatcagag atgcccggag gagggacaat gctgcatact tctttcggtt gaagtccaaa      300

tggatgaaat acggttatac atcttccaag ctctctgtgc gtgtgatggc cctgacccac      360

aggcccaaca tctccatccc agggaccctg gagtctggcc atcccagcaa tctgacctgc      420

tctgtgccct gggtctgtga gcaggggacg ccccccatct tctcctggat gtcagctgcc      480

cccacctccc tgggccccag gaccacccag tcctcggtgc tcacaatcac cccacggccc      540

caggaccaca gcaccaacct cacctgtcag gtgacgttcc ctggagccgg tgtgaccatg      600

gagagaacca tccagctcaa tgtctcctcc ttcaaaatcc tgcaaaacac ctcgtccctc      660

cctgtcctgg agggccaggc tctgcggctg ctctgtgatg ctgacggcaa cccccctgca      720

cacctgagct ggttccaggg cttccccgcc ctgaacgcca cccccatctc caataccggg      780

gtcctggagc tgcctcaagt agggtctgca gaagaaggag atttcacctg ccgtgctcag      840

catcctctgg gctccctgca aatctctctg agtctctttg tgcattggaa accagaaggc      900

agggctggtg gtgtc                                                       915


<210>  4295
<211>  1005
<212>  DNA
<213>  Homo Sapiens

<400>  4295
cagaagagta accggaagga ttactcgctg acgatgcaga gttccgtgac cgtgcaagag       60

ggcatgtgtg tccatgtgcg ctgctccttc tcctacccag tggacagcca gactgactct      120

gacccagttc atggctactg gttccgggca gggaatgata taagctggaa ggctccagtg      180

gccacaaaca acccagcttg ggcagtgcag gaggaaactc gggaccgatt ccacctcctt      240

ggggacccac agaccaaaaa ttgcaccctg agcatcagag atgccagaat gagtgatgcg      300

gggagatact tctttcgtat ggagaaagga aatataaaat ggaattataa atatgaccag      360

ctctctgtga acgtgacagc cttgacccac aggcccaaca tccttatccc cggtaccctg      420

gagtctggct gcttccagaa tctgacctgc tctgtgccct gggcctgtga gcaggggacg      480

ccccctatga tctcctggat ggggacctct gtgtcccccc tgcacccctc caccacccgc      540

tcctcagtgc tcaccctcat cccacagccc cagcaccacg gcaccagcct cacctgtcag      600

gtgaccttgc ctggggccgg cgtgaccacg aacaggacca tccaactcaa tgtgtcctac      660

cctcctcaga acttgactgt gactgtcttc caaggagaag gcacagcatc cacagctctg      720

gggaacagct catctctttc agtcctagag ggccagtctc tgcgcttggt ctgtgctgtt      780

gacagcaatc cccctgccag gctgagctgg acctggagga gtctgaccct gtacccctca      840

cagccctcaa accctctggt actggagctg caagtgcacc tgggggatga aggggaattc      900

acctgtcgag ctcagaactc tctgggttcc cagcacgttt ccctgaacct ctccctgcaa      960

caggagtaca caggcaaaat gaggcctgta tcaggagtgt tgctg                     1005


<210>  4296
<211>  1041
<212>  DNA
<213>  Homo Sapiens

<400>  4296
atggagggag acagacaata tggggatggt tacttgctgc aagtgcagga gctggtgacg       60

gtgcaggagg gcctgtgtgt ccatgtgccc tgctccttct cctaccccca ggatggctgg      120

actgactctg acccagttca tggctactgg ttccgggcag gagacagacc ataccaagac      180

gctccagtgg ccacaaacaa cccagacaga gaagtgcagg cagagaccca gggccgattc      240

caactccttg gggacatttg gagcaacgac tgctccctga gcatcagaga cgccaggaag      300

agggataagg ggtcatattt ctttcggcta gagagaggaa gcatgaaatg gagttacaaa      360

tcacagttga attacaaaac taagcagctg tctgtgtttg tgacagccct gacccatagg      420

cctgacatcc tcatcctagg gaccctagag tctggccacc ccaggaacct gacctgctct      480

gtgccctggg cctgtaagca ggggacaccc cccatgatct cctggattgg ggcctccgtg      540

tcctccccgg gccccactac tgcccgctcc tcagtgctca cccttacccc aaagccccag      600

gaccacggca ccagcctcac ctgtcaggtg accttgcctg ggacaggtgt gaccacgacc      660

agtaccgtcc gcctcgatgt gtcctaccct ccttggaact tgaccatgac tgtcttccaa      720

ggagatgcca cagcatccac agccctggga aatggctcat ctctttcagt ccttgagggc      780

cagtctctgc gcctggtctg tgctgtcaac agcaatcccc ctgccaggct gagctggacc      840

cgggggagcc tgaccctgtg cccctcacgg tcctcaaacc ctgggctgct ggagctgcct      900

cgagtgcacg tgagggatga aggggaattc acctgccgag ctcagaacgc tcagggctcc      960

cagcacattt ccctgagcct ctccctgcag aatgagggca caggcacctc aagacctgta     1020

tcacaagtga cactggcagc a                                               1041


<210>  4297
<211>  993
<212>  DNA
<213>  Homo Sapiens

<400>  4297
cagacaagta aactgctgac gatgcagagt tccgtgacgg tgcaggaagg cctgtgtgtc       60

catgtgccct gctccttctc ctacccctcg catggctgga tttaccctgg cccagtagtt      120

catggctact ggttccggga aggggccaat acagaccagg atgctccagt ggccacaaac      180

aacccagctc gggcagtgtg ggaggagact cgggaccgat tccacctcct tggggaccca      240

cataccgaga attgcaccct gagcatcaga gatgccagaa gaagtgatgc ggggagatac      300

ttctttcgta tggagaaagg aagtataaaa tggaattata aacatcaccg gctctctgtg      360

aatgtgacag ccttgaccca caggcccaac atcctcatcc caggcaccct ggagtccggc      420

tgcccccaga atctgacctg ctctgtgccc tgggcctgtg agcaggggac accccctatg      480

atctcctgga tagggacctc cgtgtccccc ctggacccct ccaccacccg ctcctcggtg      540

ctcaccctca tcccacagcc ccaggaccat ggcaccagcc tcacctgtca ggtgaccttc      600

cctggggcca gcgtgaccac gaacaagacc gtccatctca acgtgtccta cccgcctcag      660

aacttgacca tgactgtctt ccaaggagac ggcacagtat ccacagtctt gggaaatggc      720

tcatctctgt cactcccaga gggccagtct ctgcgcctgg tctgtgcagt tgatgcagtt      780

gacagcaatc cccctgccag gctgagcctg agctggagag gcctgaccct gtgcccctca      840

cagccctcaa acccgggggt gctggagctg ccttgggtgc acctgaggga tgaagctgaa      900

ttcacctgca gagctcagaa ccctctcggc tctcagcagg tctacctgaa cgtctccctg      960

cagagcaaag ccacatcagg agtgactcag ggg                                   993


<210>  4298
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  4298
gaggaggagc tgcaggtgat tcagcctgac aagtccgtat cagttgcagc tggagagtcg       60

gccattctgc actgcactgt gacctccctg atccctgtgg ggcccatcca gtggttcaga      120

ggagctggac cagcccggga attaatctac aatcaaaaag aaggccactt cccccgggta      180

acaactgttt cagagtccac aaagagagaa aacatggact tttccatcag catcagtaac      240

atcaccccag cagatgccgg cacctactac tgtgtgaagt tccggaaagg gagccctgac      300

acggagttta agtctggagc aggcactgag ctgtctgtgc gtgccaaacc ctctgccccc      360

gtggtatcgg gccctgcggc gagggccaca cctcagcaca cagtgagctt cacctgcgag      420

tcccacggct tctcacccag agacatcacc ctgaaatggt tcaaaaatgg gaatgagctc      480

tcagacttcc agaccaacgt ggaccccgta ggagagagcg tgtcctacag catccacagc      540

acagccaagg tggtgctgac ccgcgaggac gttcactctc aagtcatctg cgaggtggcc      600

cacgtcacct tgcaggggga ccctcttcgt gggactgcca acttgtctga gaccatccga      660

gttccaccca ccttggaggt tactcaacag cccgtgaggg cagagaacca ggtgaatgtc      720

acctgccagg tgaggaagtt ctacccccag agactacagc tgacctggtt ggagaatgga      780

aacgtgtccc ggacagaaac ggcctcaacc gttacagaga acaaggatgg tacctacaac      840

tggatgagct ggctcctggt gaatgtatct gcccacaggg atgatgtgaa gctcacctgc      900

caggtggagc atgacgggca gccagcggtc agcaaaagcc atgacctgaa ggtctcagcc      960

cacccgaagg agcagggctc aaataccgcc gctgagaaca ctggatctaa tgaacggaac     1020

atctat                                                                1026


<210>  4299
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  4299
gaggacgagc tacaggtgat tcagcctgaa aagtccgtat cagttgcagc tggagagtcg       60

gccactctgc gctgtgctat gacgtccctg atccctgtgg ggcccatcat gtggtttaga      120

ggagctggag caggccggga attaatctac aatcagaaag aaggccactt cccacgggta      180

acaactgttt cagaactcac aaagagaaac aacctggact tttccatcag catcagtaac      240

atcaccccag cagacgccgg cacctactac tgtgtgaagt tccggaaagg gagccctgac      300

gacgtggagt ttaagtctgg agcaggcact gagctgtctg tgcgcgccaa accctctgcc      360

cccgtggtat cgggccctgc ggtgagggcc acacctgagc acacagtgag cttcacctgc      420

gagtcccatg gcttctctcc cagagacatc accctgaaat ggttcaaaaa tgggaatgag      480

ctctcagact tccagaccaa cgtggacccc gcaggagaca gtgtgtccta cagcatccac      540

agcacagcca gggtggtgct gacccgtggg gacgttcact ctcaagtcat ctgcgagata      600

gcccacatca ccttgcaggg ggaccctctt cgtgggactg ccaacttgtc tgaggccatc      660

cgagttccac ccaccttgga ggttactcaa cagcccatga gggcagagaa ccaggcaaac      720

gtcacctgcc aggtgagcaa tttctacccc cggggactac agctgacctg gttggagaat      780

ggaaatgtgt cccggacaga aacagcttcg accctcatag agaacaagga tggcacctac      840

aactggatga gctggctcct ggtgaacacc tgtgcccaca gggacgatgt ggtgctcacc      900

tgtcaggtgg agcatgatgg gcagcaagca gtcagcaaaa gctatgccct ggagatctca      960

gcgcaccaga aggagcacgg ctcagatatc acccatgaag cagcgctggc tcctactgct     1020

ccactc                                                                1026


<210>  4300
<211>  765
<212>  DNA
<213>  Homo Sapiens

<400>  4300
caaagcagcc gtaatgactg gcaagtactt caacccgagg gtccgatgct ggttgcggag       60

ggagagaccc ttctgttacg ttgcatggtt gtgggatctt gtactgacgg gatgataaag      120

tgggtcaaag tctccacgca agaccaacaa gagatctaca attttaagag aggatctttt      180

ccgggggtca tgccgatgat acagcgtact tctgagcccc tgaattgtga ttattcaatc      240

tacattcata acgtaacgag ggagcataca ggcacctatc actgcgtgag attcgatggg      300

ttaagtgagc attctgagat gaagtctgat gaaggcactt ctgttctggt caagggcgcg      360

ggggaccccg agcctgatct ttggatcatt cagcctcaag aacttgttct aggtaccacg      420

ggcgacaccg ttttcttgaa ctgtacagtt ctaggagatg gcccgcccgg tccaatccgt      480

tggtttcaag gggctggtct aagtagggaa gcaatttaca actttggagg tatatcccat      540

ccgaaggaga cggcggtaca agcatccaat aatgatttta gcatcctact tcagaacgtg      600

tccagtgagg atgccggtac atattattgc gtcaaattcc agcgtaagcc caatagacaa      660

tacttgtcag gacagggtac gtctttgaag gtgaaagcca agagtactag ctccaaagag      720

gctgagttta cgagtgagcc cgcgactgaa atgtccccca caggg                      765


<210>  4301
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  4301
gaggaggagc tacagatgat tcagcctgag aagctcctgt tggtcacagt tggaaagaca       60

gccactctgc actgcactgt gacctccctg cttcccgtgg gacccgtcct gtggttcaga      120

ggagttggac caggccggga attaatctac aatcaaaaag aaggccactt ccccagggta      180

acaacagttt cagacctcac aaagagaaac aacatggact tttccatccg catcagtagc      240

atcaccccag cagatgtcgg cacatactac tgtgtgaagt ttcgaaaagg gagccctgag      300

aacgtggagt ttaagtctgg accaggcact gagatggctt tgggtgccaa accctctgcc      360

cccgtggtat tgggccctgc ggcgaggacc acacctgagc atacagtgag tttcacctgt      420

gagtcccatg gcttctctcc cagagacatc accctgaaat ggttcaaaaa tgggaatgag      480

ctctcagact tccagaccaa cgtggacccc acaggacaga gtgtggccta cagcatccgc      540

agcacagcca gggtggtact ggacccctgg gacgttcgct ctcaggtcat ctgcgaggtg      600

gcccatgtca ccttgcaggg ggaccctctt cgtgggactg ccaacttgtc tgaggccatc      660

cgagttccac ccaccttgga ggttactcaa cagcccatga gggtggggaa ccaggtaaac      720

gtcacctgcc aggtgaggaa gttctacccc cagagcctac agctgacctg gtcggagaat      780

ggaaacgtgt gccagagaga aacagcctcg acccttacag agaacaagga tggtacctac      840

aactggacaa gctggttcct ggtgaacata tctgaccaaa gggatgatgt ggtcctcacc      900

tgccaggtga agcatgatgg gcagctggcg gtcagcaaac gccttgccct agaggtcaca      960

gtccaccaga aggaccagag ctcagatgct acccct                                996


<210>  4302
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  4302
gcaagctacg gaacaggtgg gcgcatgatg aactgcccaa agattctccg gcagttggga       60

agcaaagtgc tgctgcccct gacatatgaa aggataaata agagcatgaa caaaagcatc      120

cacattgtcg tcacaatggc aaaatcactg gagaacagtg tcgagaacaa aatagtgtct      180

cttgatccat ccgaagcagg ccctccacgt tatctaggag atcgctacaa gttttatctg      240

gagaatctca ccctggggat acgggaaagc aggaaggagg atgagggatg gtaccttatg      300

accctggaga aaaatgtttc agttcagcgc ttttgcctgc agttgaggct ttatgagcag      360

gtctccactc cagaaattaa agttttaaac aagacccagg agaacgggac ctgcaccttg      420

atactgggct gcacagtgga gaagggggac catgtggctt acagctggag tgaaaaggcg      480

ggcacccacc cactgaaccc agccaacagc tcccacctcc tgtccctcac cctcggcccc      540

cagcatgctg acaatatcta catctgcacc gtgagcaacc ctatcagcaa caattcccag      600

accttcagcc cgtggcccgg atgcaggaca gacccctcag aaacaaaacc a               651


<210>  4303
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  4303
caaagcagct taaccccatt gatggtgaac gggattctgg gggagtcagt aactcttccc       60

ctggagtttc ctgcaggaga gaaggtcaac ttcatcactt ggcttttcaa tgaaacatct      120

cttgccttca tagtacccca tgaaaccaaa agtccagaaa tccacgtgac taatccgaaa      180

cagggaaagc gactgaactt cacccagtcc tactccctgc aactcagcaa cctgaagatg      240

gaagacacag gctcttacag agcccagata tccacaaaga cctctgcaaa gctgtccagt      300

tacactctga ggatattaag acaactgagg aacatacaag ttaccaatca cagtcagcta      360

tttcagaata tgacctgtga gctccatctg acttgctctg tggaggatgc agatgacaat      420

gtctcattca gatgggaggc cttgggaaac acactttcaa gtcagccaaa cctcactgtc      480

tcctgggacc ccaggatttc cagtgaacag gactacacct gcatagcaga gaatgctgtc      540

agtaatttat ccttctctgt ctctgcccag aagctttgcg aagatgttaa aattcaatat      600

acagatacca aaatg                                                       615


<210>  4304
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  4304
tctggacccg tgaaagagct ggtcggttcc gttggtgggg ccgtgacttt ccccctgaag       60

tccaaagtaa agcaagttga ctctattgtc tggaccttca acacaacccc tcttgtcacc      120

atacagccag aagggggcac tatcatagtg acccaaaatc gtaataggga gagagtagac      180

ttcccagatg gaggctactc cctgaagctc agcaaactga agaagaatga ctcagggatc      240

tactatgtgg ggatatacag ctcatcactc cagcagccct ccacccagga gtacgtgctg      300

catgtctacg agcacctgtc aaagcctaaa gtcaccatgg gtctgcagag caataagaat      360

ggcacctgtg tgaccaatct gacatgctgc atggaacatg gggaagagga tgtgatttat      420

acctggaagg ccctggggca agcagccaat gagtcccata atgggtccat cctccccatc      480

tcctggagat ggggagaaag tgatatgacc ttcatctgcg ttgccaggaa ccctgtcagc      540

agaaacttct caagccccat ccttgccagg aagctctgtg aaggtgctgc tgatgaccca      600

gattcctcca tg                                                          612


<210>  4305
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  4305
gcccaagtgc tgagcaaagt cgggggctcg gtgctgctgg tggcagcgcg tccccctggc       60

ttccaagtcc gtgaggctat ctggcgatct ctctggcctt cagaagagct cctggccacg      120

tttttccgag gctccctgga gactctgtac cattcccgct tcctgggccg agcccagcta      180

cacagcaacc tcagcctgga gctcgggccg ctggagtctg gagacagcgg caacttctcc      240

gtgttgatgg tggacacaag gggccagccc tggacccaga ccctccagct caaggtgtac      300

gatgcagtgc ccaggcccgt ggtacaagtg ttcattgctg tagaaaggga tgctcagccc      360

tccaagacct gccaggtttt cttgtcctgt tgggccccca acatcagcga aataacctat      420

agctggcgac gggagacaac catggacttt ggtatggaac cacacagcct cttcacagac      480

ggacaggtgc tgagcatttc cctgggacca ggagacagag atgtggccta ttcctgcatt      540

gtctccaacc ctgtcagctg ggacttggcc acagtcacgc cctgggatag ctgtcatcat      600

gaggcagcac cagggaaggc ctcctacaaa gat                                   633


<210>  4306
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  4306
aggagactct ggagatggtg tggatccgag gaagtggttg cggtccttca ggagtccatc       60

agcctccccc tggaaatacc accagatgaa gaggttgaga acatcatctg gtcctctcac      120

aaaagtcttg ccactgtggt gccagggaaa gagggacatc cagctaccat catggtgacc      180

aatccacact accagggcca agtgagcttc ctggacccca gctattccct gcatatcagc      240

aatctgagct gggaggattc agggctttac caagctcaag tcaacctgag aacatcccag      300

atctctacca tgcagcagta caatctatgt gtctaccgat ggctgtcaga gccccagatc      360

actgtgaact ttgagagttc tggggaaggt gcctgcagta tgtccctggt gtgctctgtg      420

gagaaggcag gcatggatat gacctacagc tggctctccc ggggggatag cacttataca      480

ttccatgaag gccctgtcct cagcacatcc tggaggccgg gggacagtgc cctctcctac      540

acctgcagag ccaacaaccc catcagcaac gtcagttctt gccccatccc tgatgggccc      600

ttctatgcag atcctaacta tgcttctgag aagccttcaa cagccttctg cctc            654


<210>  4307
<211>  4497
<212>  DNA
<213>  Homo Sapiens

<400>  4307
cagtgctctt gctcgggcag cacagtggac tgtcacgggc tggcgctgcg cagcgtgccc       60

aggaatatcc cccgcaacac cgagagactg gatttaaatg gaaataacat cacaagaatt      120

acgaagacag attttgctgg tcttagacat ctaagagttc ttcagcttat ggagaataag      180

attagcacca ttgaaagagg agcattccag gatcttaaag aactagagag actgcgttta      240

aacagaaatc accttcagct gtttcctgag ttgctgtttc ttgggactgc gaagctatac      300

aggcttgatc tcagtgaaaa ccaaattcag gcaatcccaa ggaaagcttt ccgtggggca      360

gttgacataa aaaatttgca actggattac aaccagatca gctgtattga agatggggca      420

ttcagggctc tccgggacct ggaagtgctc actctcaaca ataacaacat tactagactt      480

tctgtggcaa gtttcaacca tatgcctaaa cttaggactt ttcgactgca ttcaaacaac      540

ctgtattgtg actgccacct ggcctggctc tccgactggc ttcgccaaag gcctcgggtt      600

ggtctgtaca ctcagtgtat gggcccctcc cacctgagag gccataatgt agccgaggtt      660

caaaaacgag aatttgtctg cagtggtcac cagtcattta tggctccttc ttgtagtgtt      720

ttgcactgcc ctgccgcctg tacctgtagc aacaatatcg tagactgtcg tgggaaaggt      780

ctcactgaga tccccacaaa tcttccagag accatcacag aaatacgttt ggaacagaac      840

acaatcaaag tcatccctcc tggagctttc tcaccatata aaaagcttag acgaattgac      900

ctgagcaata atcagatctc tgaacttgca ccagatgctt tccaaggact acgctctctg      960

aattcacttg tcctctatgg aaataaaatc acagaactcc ccaaaagttt atttgaagga     1020

ctgttttcct tacagctcct attattgaat gccaacaaga taaactgcct tcgggtagat     1080

gcttttcagg atctccacaa cttgaacctt ctctccctat atgacaacaa gcttcagacc     1140

atcgccaagg ggaccttttc acctcttcgg gccattcaaa ctatgcattt ggcccagaac     1200

ccctttattt gtgactgcca tctcaagtgg ctagcggatt atctccatac caacccgatt     1260

gagaccagtg gtgcccgttg caccagcccc cgccgcctgg caaacaaaag aattggacag     1320

atcaaaagca agaaattccg ttgttcagct aaagaacagt atttcattcc aggtacagaa     1380

gattatcgat caaaattaag tggagactgc tttgcggatc tggcttgccc tgaaaagtgt     1440

cgctgtgaag gaaccacagt agattgctct aatcaaaagc tcaacaaaat cccggagcac     1500

attccccagt acactgcaga gttgcgtctc aataataatg aatttaccgt gttggaagcc     1560

acaggaatct ttaagaaact tcctcaatta cgtaaaataa actttagcaa caataagatc     1620

acagatattg aggagggagc atttgaagga gcatctggtg taaatgaaat acttcttacg     1680

agtaatcgtt tggaaaatgt gcagcataag atgttcaagg gattggaaag cctcaaaact     1740

ttgatgttga gaagcaatcg aataacctgt gtggggaatg acagtttcat aggactcagt     1800

tctgtgcgtt tgctttcttt gtatgataat caaattacta cagttgcacc aggggcattt     1860

gatactctcc attctttatc tactctaaac ctcttggcca atccttttaa ctgtaactgc     1920

tacctggctt ggttgggaga gtggctgaga aagaagagaa ttgtcacggg aaatcctaga     1980

tgtcaaaaac catacttcct gaaagaaata cccatccagg atgtggccat tcaggacttc     2040

acttgtgatg acggaaatga tgacaatagt tgctccccac tttctcgctg tcctactgaa     2100

tgtacttgct tggatacagt cgtccgatgt agcaacaagg gtttgaaggt cttgccgaaa     2160

ggtattccaa gagatgtcac agagttgtat ctggatggaa accaatttac actggttccc     2220

aaggaactct ccaactacaa acatttaaca cttatagact taagtaacaa cagaataagc     2280

acgctttcta atcagagctt cagcaacatg acccagctcc tcaccttaat tcttagttac     2340

aaccgtctga gatgtattcc tcctcgcacc tttgatggat taaagtctct tcgattactt     2400

tctctacatg gaaatgacat ttctgttgtg cctgaaggtg ctttcaatga tctttctgca     2460

ttatcacatc tagcaattgg agccaaccct ctttactgtg attgtaacat gcagtggtta     2520

tccgactggg tgaagtcgga atataaggag cctggaattg ctcgttgtgc tggtcctgga     2580

gaaatggcag ataaactttt actcacaact ccctccaaaa aatttacctg tcaaggtcct     2640

gtggatgtca atattctagc taagtgtaac ccctgcctat caaatccgtg taaaaatgat     2700

ggcacatgta atagtgatcc agttgacttt taccgatgca cctgtccata tggtttcaag     2760

gggcaggact gtgatgtccc aattcatgcc tgcatcagta acccatgtaa acatggagga     2820

acttgccact taaaggaagg agaagaagat ggattctggt gtatttgtgc tgatggattt     2880

gaaggagaaa attgtgaagt caacgttgat gattgtgaag ataatgactg tgaaaataat     2940

tctacatgtg tcgatggcat taataactac acatgccttt gcccacctga gtatacaggt     3000

gagttgtgtg aggagaagct ggacttctgt gcccaggacc tgaacccctg ccagcacgat     3060

tcaaagtgca tcctaactcc aaagggattc aaatgtgact gcacaccagg gtacgtaggt     3120

gaacactgcg acatcgattt tgacgactgc caagacaaca agtgtaaaaa cggagcccac     3180

tgcacagatg cagtgaacgg ctatacgtgc atatgccccg aaggttacag tggcttgttc     3240

tgtgagtttt ctccacccat ggtcctccct cgtaccagcc cctgtgataa ttttgattgt     3300

cagaatggag ctcagtgtat cgtcagaata aatgagccaa tatgtcagtg tttgcctggc     3360

tatcagggag aaaagtgtga aaaattggtt agtgtgaatt ttataaacaa agagtcttat     3420

cttcagattc cttcagccaa ggttcggcct cagacgaaca taacacttca gattgccaca     3480

gatgaagaca gcggaatcct cctgtataag ggtgacaaag accatatcgc ggtagaactc     3540

tatcgggggc gtgttcgtgc cagctatgac accggctctc atccagcttc tgccatttac     3600

agtgtggaga caatcaatga tggaaacttc cacattgtgg aactacttgc cttggatcag     3660

agtctctctt tgtccgtgga tggtgggaac cccaaaatca tcactaactt gtcaaagcag     3720

tccactctga attttgactc tccactctat gtaggaggca tgccagggaa gagtaacgtg     3780

gcatctctgc gccaggcccc tgggcagaac ggaaccagct tccacggctg catccggaac     3840

ctttacatca acagtgagct gcaggacttc cagaaggtgc cgatgcaaac aggcattttg     3900

cctggctgtg agccatgcca caagaaggtg tgtgcccatg gcacatgcca gcccagcagc     3960

caggcaggct tcacctgcga gtgccaggaa ggatggatgg ggcccctctg tgaccaacgg     4020

accaatgacc cttgccttgg aaataaatgc gtacatggca cctgcttgcc catcaatgcg     4080

ttctcctaca gctgtaagtg cttggagggc catggaggtg tcctctgtga tgaagaggag     4140

gatctgttta acccatgcca ggcgatcaag tgcaagcatg ggaagtgcag gctttcaggt     4200

ctggggcagc cctactgtga atgcagcagt ggatacacgg gggacagctg tgatcgagaa     4260

atctcttgtc gaggggaaag gataagagat tattaccaaa agcagcaggg ctatgctgct     4320

tgccaaacaa ccaagaaggt gtcccgatta gagtgcagag gtgggtgtgc aggagggcag     4380

tgctgtggac cgctgaggag caagcggcgg aaatactctt tcgaatgcac tgacggctcc     4440

tcctttgtgg acgaggttga gaaagtggtg aagtgcggct gtacgaggtg tgtgtcc        4497


<210>  4308
<211>  1584
<212>  DNA
<213>  Homo Sapiens

<400>  4308
aacccagatg actgtgagga caacgactgc gaaaacaatg ccacctgcgt ggacgggatc       60

aacaactacg tgtgtatctg tccgcctaac tacacaggtg agctatgcga cgaggtgatt      120

gaccactgtg tgcctgagct gaacctctgt cagcatgagg ccaagtgcat ccccctggac      180

aaaggattca gctgcgagtg tgtccctggc tacagcggga agctctgtga gacagacaat      240

gatgactgtg tggcccacaa gtgccgccac ggggcccagt gcgtggacac aatcaatggc      300

tacacatgca cctgccccca gggcttcagt ggacccttct gtgaacaccc cccacccatg      360

gtcctactgc agaccagccc atgcgaccag tacgagtgcc agaacggggc ccagtgcatc      420

gtggtgcagc aggagcccac ctgccgctgc ccaccaggct tcgccggccc cagatgcgag      480

aagctcatca ctgtcaactt cgtgggcaaa gactcctacg tggaactggc ctccgccaag      540

gtccgacccc aggccaacat ctccctgcag gtggccactg acaaggacaa cggcatcctt      600

ctctacaaag gagacaatga ccccctggca ctggagctgt accagggcca cgtgcggctg      660

gtctatgaca gcctgagttc ccctccaacc acagtgtaca gtgtggagac agtgaatgat      720

gggcagtttc acagtgtgga gctggtgacg ctaaaccaga ccctgaacct agtagtggac      780

aaaggaactc caaagagcct ggggaagctc cagaagcagc cagcagtggg catcaacagc      840

cccctctacc ttggaggcat ccccacctcc accggcctct ccgccttgcg ccagggcacg      900

gaccggcctc taggcggctt ccacggatgc atccatgagg tgcgcatcaa caacgagctg      960

caggacttca aggccctccc accacagtcc ctgggggtgt caccaggctg caagtcctgc     1020

accgtgtgca agcacggcct gtgccgctcc gtggagaagg acagcgtggt gtgcgagtgc     1080

cgcccaggct ggaccggccc actctgcgat caggaggccc gggacccctg cctcggccac     1140

agatgccacc atggaaaatg tgtggcaact gggacctcat acatgtgcaa gtgtgccgag     1200

ggctatggag gggacttgtg tgacaacaag aatgactctg ccaatgcctg ctcagccttc     1260

aagtgtcacc atgggcagtg ccacatctca gaccaagggg agccctactg cctgtgccag     1320

cccggcttta gcggcgagca ctgccaacaa gagaatccgt gcctgggaca agtagtccga     1380

gaggtgatcc gccgccagaa aggttatgca tcatgtgcca cagcctccaa ggtgcccatc     1440

atggaatgtc gtgggggctg tgggccccag tgctgccagc ccacccgcag caagcggcgg     1500

aaatacgtct tccagtgcac ggatggctcc tcgtttgtag aagaggtgga gagacactta     1560

gagtgcggct gcctcgcgtg ttcc                                            1584


<210>  4309
<211>  1815
<212>  DNA
<213>  Homo Sapiens

<400>  4309
aacgttacag gggacgtttg caaagagaag atctgttcct gcaatgagat agaaggggac       60

ctacacgtag actgtgaaaa aaagggcttc acaagtctgc agcgtttcac tgccccgact      120

tcccagtttt accatttatt tctgcatggc aattccctca ctcgactttt ccctaatgag      180

ttcgctaact tttataatgc ggttagtttg cacatggaaa acaatggctt gcatgaaatc      240

gttccggggg cttttctggg gctgcagctg gtgaaaaggc tgcacatcaa caacaacaag      300

atcaagtctt ttcgaaagca gacttttctg gggctggacg atctggaata tctccaggct      360

gattttaatt tattacgaga tatagacccg ggggccttcc aggacttgaa caagctggag      420

gtgctcattt taaatgacaa tctcatcagc accctacctg ccaacgtgtt ccagtatgtg      480

cccatcaccc acctcgacct ccggggtaac aggctgaaaa cgctgcccta tgaggaggtc      540

ttggagcaaa tccctggtat tgcggagatc ctgctagagg ataacccttg ggactgcacc      600

tgtgatctgc tctccctgaa agaatggctg gaaaacattc ccaagaatgc cctgatcggc      660

cgagtggtct gcgaagcccc caccagactg cagggtaaag acctcaatga aaccaccgaa      720

caggacttgt gtcctttgaa aaaccgagtg gattctagtc tcccggcgcc ccctgcccaa      780

gaagagacct ttgctcctgg acccctgcca actcctttca agacaaatgg gcaagaggat      840

catgccacac cagggtctgc tccaaacgga ggtacaaaga tcccaggcaa ctggcagatc      900

aaaatcagac ccacagcagc gatagcgacg ggtagctcca ggaacaaacc cttagctaac      960

agtttaccct gccctggggg ctgcagctgc gaccacatcc cagggtcggg tttaaagatg     1020

aactgcaaca acaggaacgt gagcagcttg gctgatttga agcccaagct ctctaacgtg     1080

caggagcttt tcctacgaga taacaagatc cacagcatcc gaaaatcgca ctttgtggat     1140

tacaagaacc tcattctgtt ggatctgggc aacaataaca tcgctactgt agagaacaac     1200

tctttcaaga accttttgga cctcaggtgg ctatacatgg atagcaatta cctggacacg     1260

ctgtcccggg agaaattcgc ggggctgcaa aacctagagt acctgaacgt ggagtacaac     1320

gctatccagc tcatcctccc gggcactttc aatgccatgc ccaaactgag gatcctcatt     1380

ctcaacaaca acctgctgag gtccctgcct gtggacgtgt tcgctggggt ctcgctctct     1440

aaactcagcc tgcacaacaa ttacttcatg tacctcccgg tggcaggggt gctggaccag     1500

ttaacctcca tcatccagat agacctccac ggaaacccct gggagtgctc ctgcacaatt     1560

gtgcctttca agcagtgggc agaacgcttg ggttccgaag tgctgatgag cgacctcaag     1620

tgtgagacgc cggtgaactt ctttagaaag gatttcatgc tcctctccaa tgacgagatc     1680

tgccctcagc tgtacgctag gatctcgccc acgttaactt cgcacagtaa aaacagcact     1740

gggttggcgg agaccgggac gcactccaac tcctacctag acaccagcag ggtgtccatc     1800

tcggtgttgg tcccg                                                      1815


<210>  4310
<211>  1800
<212>  DNA
<213>  Homo Sapiens

<400>  4310
cgcaaaactg ccaaagacat ttgcaagatc cgctgtctgt gcgaagaaaa ggaaaacgta       60

ctgaatatca actgtgagaa caaaggattt acaacagtta gcctgctcca gcccccccag      120

tatcgaatct atcagctttt tctcaatgga aacctcttga caagactgta tccaaacgaa      180

tttgtcaatt actccaacgc ggtgactctt cacctaggta acaacgggtt acaggagatc      240

cgaacggggg cattcagtgg cctgaaaact ctcaaaagac tgcatctcaa caacaacaag      300

cttgagatat tgagggagga caccttccta ggcctggaga gcctggagta tctccaggcc      360

gactacaatt acatcagtgc catcgaggct ggggcattca gcaaacttaa caagctcaaa      420

gtgctcatcc tgaatgacaa ccttctgctt tcactgccca gcaatgtgtt ccgctttgtc      480

ctgctgaccc acttagacct cagggggaat aggctaaaag taatgccttt tgctggcgtc      540

cttgaacata ttggagggat catggagatt cagctggagg aaaatccatg gaattgcact      600

tgtgacttac ttcctctcaa ggcctggcta gacaccataa ctgtttttgt gggagagatt      660

gtctgtgaga ctccctttag gttgcatggg aaagacgtga cccagctgac caggcaagac      720

ctctgtccca gaaaaagtgc cagtgattcc agtcagaggg gcagccatgc tgacacccac      780

gtccaaaggc tgtcacctac aatgaatcct gctctcaacc caaccagggc tccgaaagcc      840

agccggccgc ccaaaatgag aaatcgtcca actccccgag tgactgtgtc aaaggacagg      900

caaagttttg gacccatcat ggtgtaccag accaagtctc ctgtgcctct cacctgtccc      960

agcagctgtg tctgcacctc tcagagctca gacaatggtc tgaatgtaaa ctgccaagaa     1020

aggaagttca ctaatatctc tgacctgcag cccaaaccga ccagtccaaa gaaactctac     1080

ctaacaggga actatcttca aactgtctat aagaatgacc tcttagaata cagttctttg     1140

gacttactgc acttaggaaa caacaggatt gcagtcattc aggaaggtgc ctttacaaac     1200

ctgaccagtt tacgcagact ttatctgaat ggcaattacc ttgaagtgct gtacccttct     1260

atgtttgatg gactgcagag cttgcaatat ctctatttag agtataatgt cattaaggaa     1320

attaagcctc tgacctttga tgctttgatt aacctacagc tactgtttct gaacaacaac     1380

cttcttcggt ccttacctga taatatattt ggggggacgg ccctaaccag gctgaatctg     1440

agaaacaacc atttttctca cctgcccgtg aaaggggttc tggatcagct cccggctttc     1500

atccagatag atctgcagga gaacccctgg gactgtacct gtgacatcat ggggctgaaa     1560

gactggacag aacatgccaa ttcccctgtc atcattaatg aggtgacttg cgaatctcct     1620

gctaagcatg caggggagat actaaaattt ctggggaggg aggctatctg tccagacagc     1680

ccaaacttgt cagatggaac cgtcttgtca atgaatcaca atacagacac acctcggtcg     1740

cttagtgtgt ctcctagttc ctatcctgaa ctacacactg aagttccact gtctgtctta     1800


<210>  4311
<211>  1878
<212>  DNA
<213>  Homo Sapiens

<400>  4311
accccgattc ccctaataga ggactcagag gaaatagatg agccctgttt tgatccatgc       60

tactgtgaag ttaaagaaag cctctttcat atacattgtg acagtaaagg atttacaaat      120

attagtcaga ttaccgagtt ctggtcaaga ccttttaaac tgtatctgca gaggaattct      180

atgaggaaat tatataccaa cagttttctt catttgaata atgctgtgtc tattaatctt      240

gggaacaatg cattgcagga cattcagact ggagctttca atggtcttaa gattttaaag      300

agactatatc tacatgaaaa caaactagat gtcttcagaa atgacacctt ccttggcttg      360

gaaagtctag aatatctgca ggcagattac aatgtcatta aacgtattga gagtggggca      420

tttcggaacc taagtaaatt gagggttctg attttaaatg ataatctcat ccccatgctt      480

ccaaccaatt tatttaaggc tgtctcttta acccatttgg acctacgtgg aaataggtta      540

aaggttcttt tttaccgagg aatgctagat cacattggca gaagcctgat ggagctccag      600

ctggaagaaa acccttggaa ctgtacatgt gaaattgtac aactgaagag ttggctggaa      660

cgcattcctt atactgccct ggtgggagac attacctgtg agaccccttt ccacttccat      720

ggaaaggacc tacgagaaat caggaagaca gaactctgtc ccttgttgtc tgactctgag      780

gtagaggcta gtttgggaat tccacattcg tcatcaagta aggagaatgc atggccaact      840

aagccttcct caatgctatc ctctgttcat tttactgctt cttctgtcga atacaagtcc      900

tcaaataaac agcctaagcc caccaaacag cctcgaacac caaggccacc ctccacctcc      960

caagctttat atcctggtcc aaaccagcct cccattgctc cttatcagac cagaccacca     1020

atccccatta tatgccccac tgggtgtacc tgtaatttgc acatcaatga ccttggcttg     1080

actgtcaact gcaaagagcg aggatttaat aacatttctg aacttcttcc aaggcccttg     1140

aatgccaaga aactgtatct gagtagcaat ctgattcaga aaatataccg ttctgatttt     1200

tggaattttt cttccttgga tctcttgcat ctggggaaca atcgtatttc ctatgtccaa     1260

gatggggcct ttatcaactt gcccaactta aagagcctct tccttaatgg caacgatata     1320

gagaagctga caccaggcat gttccgaggc ctacagagtt tgcactactt gtactttgag     1380

ttcaatgtca tccgggaaat ccagcctgca gccttcagcc tcatgcccaa cttgaagctg     1440

ctattcctca ataataactt actgaggact ctgccaacag acgcctttgc tggcacatcc     1500

ctggcccggc tcaacctgag gaagaactac ttcctctatc ttcccgtggc tggtgtcctg     1560

gaacacttga atgccattgt ccagatagac ctcaatgaga atccttggga ctgcacctgt     1620

gacctggtcc cctttaaaca gtggatcgaa accatcagct cagtcagtgt ggttggtgat     1680

gtgctttgca ggagccctga gaacctcacg caccgtgatg tgcgcactat tgagctggaa     1740

gttctttgcc cagagatgct gcacgttgca ccagctggag aatccccagc ccagcctgga     1800

gattctcacc ttattggggc accaaccagt gcatcacctt atgagttttc tcctcctggg     1860

ggccctgtgc cactttct                                                   1878


<210>  4312
<211>  1800
<212>  DNA
<213>  Homo Sapiens

<400>  4312
gattctgaca tatcggtgga aatttgcaat gtgtgttcct gcgtgtcagt tgagaatgtg       60

ctctatgtca actgtgagaa ggtttcagtc tacagaccaa atcagctgaa accaccttgg      120

tctaattttt atcacctcaa tttccaaaat aattttttaa atattctgta tccaaataca      180

ttcttgaatt tttcacatgc agtctccctg catctgggga ataataaact gcagaacatt      240

gagggaggag cctttcttgg gctcagtgca ttaaagcagt tgcacttgaa caacaatgaa      300

ttaaagattc tccgagctga cactttcctt ggcatagaga acttggagta tctccaggct      360

gactacaatt taatcaagta tattgaacga ggagccttca ataagctcca caaactgaaa      420

gttctcattc ttaatgacaa tctgatttca ttccttcctg ataatatttt ccgattcgca      480

tctttgaccc atctggatat acgagggaac agaatccaga agctccctta tatcggggtt      540

ctggaacaca ttggccgtgt cgttgaattg caactggaag ataacccttg gaactgtagc      600

tgtgatttat tgcccttaaa agcttggctg gagaacatgc catataacat ttacatagga      660

gaagctatct gtgaaactcc cagtgactta tatggaaggc ttttaaaaga aaccaacaaa      720

caagagctat gtcccatggg caccggcagt gattttgacg tgcgcatcct gcctccatct      780

cagctggaaa atggctacac cactcccaat ggtcacacta cccaaacatc tttacacaga      840

ttagtaacta aaccaccaaa aacaacaaat ccttccaaga tctctggaat cgttgcaggc      900

aaagccctct ccaaccgcaa tctcagtcag attgtgtctt accaaacaag ggtgcctcct      960

ctaacacctt gcccggcacc ttgcttctgc aaaacacacc cttcagattt gggactaagt     1020

gtgaactgcc aagagaaaaa tatacagtct atgtctgaac tgataccgaa acctttaaat     1080

gcgaagaagc tgcacgtcaa tggcaatagc atcaaggatg tggacgtatc agacttcact     1140

gactttgaag gactggattt gcttcattta ggcagcaatc aaattacagt gattaaggga     1200

gacgtatttc acaatctcac taatttacgc aggctatatc tcaatggcaa tcaaattgag     1260

agactctatc ctgaaatatt ttcaggtctt cataacctgc agtatctgta tttggaatac     1320

aatttgatta aggaaatctc agcaggcacc tttgactcca tgccaaattt gcagttactg     1380

tacttaaaca ataatctcct aaagagcctg cctgtttaca tcttttccgg agcaccctta     1440

gctagactga acctgaggaa caacaaattc atgtacctgc ctgtcagtgg ggtccttgat     1500

cagttgcaat ctcttacaca gattgacttg gagggcaacc catgggactg tacttgtgac     1560

ttggtggcat taaagctgtg ggtggagaag ttgagcgacg ggattgttgt gaaagaactg     1620

aaatgtgaga cgcctgttca gtttgccaac attgaactga agtccctcaa aaatgaaatc     1680

ttatgtccca aacttttaaa taagccgtct gcaccattca caagccctgc acctgccatt     1740

acattcacca ctcctttggg tcccattcga agtcctcctg gtgggccagt gcctctgtct     1800


<210>  4313
<211>  1872
<212>  DNA
<213>  Homo Sapiens

<400>  4313
atcgattatt atggggaaat ctgtgacaat gcatgtcctt gtgaggaaaa ggacggcatt       60

ttaactgtga gctgtgaaaa ccgggggatc atcagtctct ctgaaattag ccctccccgt      120

ttcccaatct accacctctt gttgtccgga aaccttttga accgtctcta tcccaatgag      180

tttgtcaatt acactggggc ttcaattttg catctaggta gcaatgttat ccaggacatt      240

gagaccgggg ctttccatgg gctacggggt ttgaggagat tgcatctaaa caataataaa      300

ctggaacttc tgcgagatga taccttcctt ggcttggaga acctggagta cctacaggtc      360

gattacaact acatcagcgt cattgaaccc aatgcttttg ggaaactgca tttgttgcag      420

gtgcttatcc tcaatgacaa tcttttgtcc agtttaccca acaatctttt ccgttttgtg      480

cccttaacgc acttggacct ccgggggaac cggctgaaac ttctgcccta cgtggggctc      540

ttgcagcaca tggataaagt tgtggagcta cagctggagg aaaacccttg gaattgttct      600

tgtgagctga tctctctaaa ggattggttg gacagcatct cctattcagc cctggtgggg      660

gatgtagttt gtgagacccc cttccgctta cacggaaggg acttggacga ggtatccaag      720

caggaacttt gcccaaggag acttatttct gactacgaga tgaggccgca gacgcctttg      780

agcaccacgg ggtatttaca caccaccccg gcgtcagtga attctgtggc cacttcttcc      840

tctgctgttt acaaaccccc tttgaagccc cctaagggga ctcgccaacc caacaagccc      900

agggtgcgcc ccacctctcg gcagccctct aaggacttgg gctacagcaa ctatggcccc      960

agcatcgcct atcagaccaa atccccggtg cctttggagt gtcccaccgc gtgctcttgc     1020

aacctgcaga tctctgatct gggcctcaac gtaaactgcc aggagcgaaa gatcgagagc     1080

atcgctgaac tgcagcccaa gccctacaat cccaagaaaa tgtatctgac agagaactac     1140

atcgctgtcg tgcgcaggac agacttcctg gaggccacgg ggctggacct cctgcacctg     1200

gggaataacc gcatctcgat gatccaggac cgcgctttcg gggatctcac caacctgagg     1260

cgcctctacc tgaatggcaa caggatcgag aggctgagcc cggagttatt ctatggcctg     1320

cagagcctgc agtatctctt cctccagtac aatctcatcc gcgagattca gtctggaact     1380

tttgacccgg tcccaaacct ccagctgcta ttcttgaata acaacctcct gcaggccatg     1440

ccctcaggcg tcttctctgg cttgaccctc ctcaggctaa acctgaggag taaccacttc     1500

acctccttgc cagtgagtgg agttttggac cagctgaagt cactcatcca aatcgacctg     1560

catgacaatc cttgggattg tacctgtgac attgtgggca tgaagctgtg ggtggagcag     1620

ctcaaagtgg gcgtcctagt ggacgaggtg atctgtaagg cgcccaaaaa attcgctgag     1680

accgacatgc gctccattaa gtcggagctg ctgtgccctg actattcaga tgtagtagtt     1740

tccacgccca caccctcctc tatccaggtc cctgcgagga ccagcgccgt gactcctgcg     1800

gtccggttga atagcaccgg ggcccccgcg agcttgggcg caggcggagg ggcgtcgtcg     1860

gtgcccttgt ct                                                         1872


<210>  4314
<211>  1746
<212>  DNA
<213>  Homo Sapiens

<400>  4314
tccagaggct cttgtgattc tctttgcaat tgtgaggaaa aagatggcac aatgctaata       60

aattgtgaag caaaaggtat caagatggta tctgaaataa gtgtgccacc atcacgacct      120

ttccaactaa gcttattaaa taacggcttg acgatgcttc acacaaatga cttttctggg      180

cttaccaatg ctatttcaat acaccttgga tttaacaata ttgcagatat tgagataggt      240

gcatttaatg gccttggcct cctgaaacaa cttcatatca atcacaattc tttagaaatt      300

cttaaagagg atactttcca tggactggaa aacctggaat tcctgcaagc agataacaat      360

tttatcacag tgattgaacc aagtgccttt agcaagctca acagactcaa agtgttaatt      420

ttaaatgaca atgctattga gagtcttcct ccaaacatct tccgatttgt tcctttaacc      480

catctagatc ttcgtggaaa tcaattacaa acattgcctt atgttggttt tctcgaacac      540

attggccgaa tattggatct tcagttggag gacaacaaat gggcctgcaa ttgtgactta      600

ttgcagttaa aaacttggtt ggagaacatg cctccacagt ctataattgg tgatgttgtc      660

tgcaacagcc ctccattttt taaaggaagt atactcagta gactaaagaa ggaatctatt      720

tgccctactc caccagtgta tgaagaacat gaggatcctt caggatcatt acatctggca      780

gcaacatctt caataaatga tagtcgcatg tcaactaaga ccacgtccat tctaaaacta      840

cccaccaaag caccaggttt gataccttat attacaaagc catccactca acttccagga      900

ccttactgcc ctattccttg taactgcaaa gtcctatccc catcaggact tctaatacat      960

tgtcaggagc gcaacattga aagcttatca gatctgagac ctcctccgca aaatcctaga     1020

aagctcattc tagcgggaaa tattattcac agtttaatga agtctgatct agtggaatat     1080

ttcactttgg aaatgcttca cttgggaaac aatcgtattg aagttcttga agaaggatcg     1140

tttatgaacc taacgagatt acaaaaactc tatctaaatg gtaaccacct gaccaaatta     1200

agtaaaggca tgttccttgg tctccataat cttgaatact tatatcttga atacaatgcc     1260

attaaggaaa tactgccagg aacctttaat ccaatgccta aacttaaagt cctgtattta     1320

aataacaacc tcctccaagt tttaccacca catatttttt caggggttcc tctaactaag     1380

gtaaatctta aaacaaacca gtttacccat ctacctgtaa gtaatatttt ggatgatctt     1440

gatttgctaa cccagattga ccttgaggat aacccctggg actgctcctg tgacctggtt     1500

ggactgcagc aatggataca aaagttaagc aagaacacag tgacagatga catcctctgc     1560

acttcccccg ggcatctcga caaaaaggaa ttgaaagccc taaatagtga aattctctgt     1620

ccaggtttag taaataaccc atccatgcca acacagacta gttaccttat ggtcaccact     1680

cctgcaacaa caacaaatac ggctgatact attttacgat ctcttacgga cgctgtgcca     1740

ctgtct                                                                1746


<210>  4315
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  4315
ctcaagtgct acacctgcaa ggagcccatg accagtgctt cctgcaggac cattacccgc       60

tgcaagccag aggacacagc ctgcatgacc acgctggtga cggtggaggc agagtacccc      120

ttcaaccaga gccccgtggt gacccgctcc tgctccagct cctgtgtggc caccgacccc      180

gacagcatcg gggccgccca cctgatcttc tgctgcttcc gagacctctg caactcggaa      240

ctc                                                                    243


<210>  4316
<211>  1800
<212>  DNA
<213>  Homo Sapiens

<400>  4316
atgcacggaa tcctgggggc atgtgggcgc ctcagacttg agccagcaac acccttgaca       60

ccccttctct gtgcagagag ggatgagtgc cgagctcacc cgtgcagaaa tggagggtcc      120

tgcaggaacc tcccaggggc ctatgtctgc cggtgccctg caggcttcgt tggagtccac      180

tgtgagacag aggtggacgc ctgcgactcc agcccctgcc agcatggagg ccggtgtgag      240

agcggcggtg gggcctacct gtgcgtctgc ccagagagct tcttcggcta ccactgcgag      300

acagtgagtg acccctgctt ctccagcccc tgtgggggcc gtggctattg cctggccagc      360

aacggctccc acagctgcac ctgcaaagtg ggctacacgg gcgaggactg cgccaaagag      420

ctcttcccac cgacggccct caagatggag agagtggagg agagtggggt ctctatctcc      480

tggaacccgc ccaatggtcc agccgccagg cagatgcttg atggctacgc ggtcacctac      540

gtctcctccg acggctccta ccgccgcacg gactttgtgg acaggacccg ctcctcgcac      600

cagctccagg ccctggcggc cggcagggcc tacaacatct ccgtcttctc agtgaagcga      660

aacagtaaca acaagaatga catcagcagg cctgccgtgc tgctggcccg cacgcgaccc      720

cgccctgtgg aaggcttcga ggtcaccaat gtgacggcta gcaccatctc agtgcagtgg      780

gccctgcaca ggatccgcca tgccaccgtc agtggggtcc gtgtgtccat ccgccaccct      840

gaggccctca gggaccaggc caccgatgtg gacaggagtg tggacaggtt cacctttagg      900

gccctgctgc ctgggaagag gtacaccatc cagctgacca ccctcagtgg gctcagggga      960

gaggagcacc ccacagagag cctggccacc gcgccgacgc acgtgtggac ccggcccctg     1020

cctccagcaa acctgaccgc cgcccgagtc actgccacct ctgcccacgt ggtctgggat     1080

gccccgactc caggcagctt gctggaggct tatgtcatca atgtgaccac cagccagagc     1140

accaagagcc gctatgtccc caacgggaag ctggcgtcct acacggtgcg cgacctgctg     1200

ccgggacggc ggtaccagct ctctgtgata gcagtgcaga gcacggagct cgggccgcag     1260

cacagcgagc ccgcccacct ctacatcatc acctccccca gggatggcgc tgacagacgc     1320

tggcaccagg gaggacacca ccctcgggtg ctcaagaaca gaccgccccc ggcgcgcctg     1380

ccggagctgc gcctgctcaa tgaccacagc gcccccgaga cccccaccca gccccccagg     1440

ttctcggagc ttgtggacgg cagaggaaga gtgagcgcca ggttcggtgg ctcacccagc     1500

aaagcagcca ccgtgagatc acacgtccct ggcaactgtt cagaaaaccc ctgtcagaac     1560

ggaggcactt gtgtgccggg cgcagacgcc cacagctgtg actgcgggcc agggttcaaa     1620

ggcagacgct gcgagctcgc ctgtataaag gtgtcccgcc cctgcacaag gctgttctcc     1680

gagacaaagt cctttccagt ctgggaggga ggcgtctgtc accacgtgta taaaagagtc     1740

taccgagttc accaagacat ctgcttcaaa gagagctgtg aaagcacaag cctcaaacta     1800


<210>  4317
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  4317
gtcaaggact gcgtcttctg tgagctcacc gactccatgc agtgtcctgg tacctacatg       60

cactgtggcg atgacgagga ctgcttcaca ggccacgggg tcgccccggg cactggtccg      120

gtcatcaaca aaggctgcct gcgagccacc agctgcggcc ttgaggaacc cgtcagctac      180

aggggcgtca cctacagcct caccaccaac tgctgcaccg gccgcctgtg taac            234


<210>  4318
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  4318
tgtctcctct gcttcacaac ctactctgag cgcctccgca tctgccagat gtttgttggg       60

atgcggagcc ccaagcttga agagtgtgag gaggccttca cggccgcctt ccagggcctc      120

tctgacaccg aaatcagtga ggagaccatc cacacttcat cagtgtcctg gggaaggtgc      180

agagggaggg caggagaggc ccagagggtc aggctgaggg acagacagag agaaacagtc      240

agaggagaaa ggctcaaaga ccatgagaac aacagagact tagggacaga gagacacaga      300

caggggaaga cagcagggca aagactcaga gaggggagga tggagagtca gagaggggaa      360

gatggagact cagagagggg gaggatggag actcagagag agaggaagat ggagactcgg      420

aaagatggag actcaggagt atggagagtc agagagggga ggatggacac tcgggaggat      480

ggagagtcag gaggatggag actcatagaa aggggaggat ggagagtcag gagaggttgg      540

agactggaga gggaa                                                       555


<210>  4319
<211>  1434
<212>  DNA
<213>  Homo Sapiens

<400>  4319
gggccaccgc ccgcgccccc tgggctgccc gcgggagccg actgcctgaa cagctttacc       60

gccggggtgc ctggcttcgt gctggacacc aacgcctcgg tcagcaacgg agctaccttc      120

ctggagtccc ccaccgtgcg ccggggctgg gactgcgtgc gcgcctgctg caccacccag      180

aactgcaact tggcgctagt ggagctgcag cccgaccgcg gggaggacgc catcgccgcc      240

tgcttcctca tcaactgcct ctacgagcag aacttcgtgt gcaagttcgc gcccagggag      300

ggcttcatca actacctcac gagggaagtg taccgctcct accgccagct gcggacccag      360

ggctttggag ggtctgggat ccccaaggcc tgggcaggca tagacttgaa ggtacaaccc      420

caggaacccc tggtgctgaa ggatgtggaa aacacagatt ggcgcctact gcggggtgac      480

acggatgtca gggtagagag gaaagaccca aaccaggtgg aactgtgggg actcaaggaa      540

ggcacctacc tgttccagct gacagtgact agctcagacc acccagagga cacggccaac      600

gtcacagtca ctgtgctgtc caccaagcag acagaagact actgcctcgc atccaacaag      660

gtgggtcgct gccggggctc tttcccacgc tggtactatg accccacgga gcagatctgc      720

aagagtttcg tttatggagg ctgcttgggc aacaagaaca actaccttcg ggaagaagag      780

tgcattctag cctgtcgggg tgtgcaaggc ccctccatgg aaaggcgcca tccagtgtgc      840

tctggcacct gtcagcccac ccagttccgc tgcagcaatg gctgctgcat cgacagtttc      900

ctggagtgtg acgacacccc caactgcccc gacgcctccg acgaggctgc ctgtgaaaaa      960

tacacgagtg gctttgacga gctccagcgc atccatttcc ccagtgacaa agggcactgc     1020

gtggacctgc cagacacagg actctgcaag gagagcatcc cgcgctggta ctacaacccc     1080

ttcagcgaac actgcgcccg ctttacctat ggtggttgtt atggcaacaa gaacaacttt     1140

gaggaagagc agcagtgcct cgagtcttgt cgcggcatct ccaagaagga tgtgtttggc     1200

ctgaggcggg aaatccccat tcccagcaca ggctctgtgg agatggctgt cgcagtgttc     1260

ctggtcatct gcattgtggt ggtggtagcc atcttgggtt actgcttctt caagaaccag     1320

agaaaggact tccacggaca ccaccaccac ccaccaccca cccctgccag ctccactgtc     1380

tccactaccg aggacacgga gcacctggtc tataaccaca ccacccggcc cctc           1434


<210>  4320
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  4320
ttcccaggat cgggagactc accactagaa gacgatgaag tcgggtattc acaccctaga       60

tataaagata ccccgtggtg ctcccccatc aaggtgaagt atggggatgt gtactgcagg      120

gcccctcaag gaggatacta caaaacagcc ctgggaacca ggtgcgacat tcgctgccag      180

aagggctacg agctgcatgg ctcttcccta ctgatctgcc agtcaaacaa acgatggtct      240

gacaaggtca tctgcaaaca aaagcgatgt cctacccttg ccatgccagc aaatggaggg      300

tttaagtgtg tagatggtgc ctactttaac tcccggtgtg agtattattg ttcaccagga      360

tacacgttga aaggggagcg gaccgtcaca tgtatggaca acaaggcctg gagcggccgg      420

ccagcctcct gtgtggatat ggaacctcct agaatcaagt gcccaagtgt gaaggaacgc      480

attgcagaac ccaacaaact gacagtccgg gtgtcctggg agacacccga aggaagagac      540

acagcagatg gaattcttac tgatgtcatt ctaaaaggcc tccccccagg ctccaacttt      600

ccagaaggag accacaagat ccagtacaca gtctatgaca gagctgagaa taagggcact      660

tgcaaatttc gagttaaagt aagagtcaaa cgctgtggca aactcaatgc cccagagaat      720

ggttacatga agtgctccag cgacggtgat aattatggag ccacctgtga gttctcctgc      780

atcggcggct atgagctcca gggtagccct gcccgagtat gtcaatccaa cctggcttgg      840

tctggcacgg agcccacctg tgcagccatg aacgtcaatg tgggtgtcag aacggcagct      900

gcacttctgg atcagtttta tgagaaaagg agactcctca ttgtgtccac acccacagcc      960

cgaaacctcc tttaccggct ccagctagga atgctgcagc aagcacagtg tggccttgat     1020

cttcgacaca tcaccgtggt ggagctggtg ggtgtgttcc cgactctcat tggcaggata     1080

ggagcaaaga ttatgcctcc agccctagcg ctgcagctca ggctgttgct gcgaatccca     1140

ctctactcct tcagtatggt gctagtggat aagcatggca tggacaaaga gcgctatgtc     1200

tccctggtga tgcctgtggc cctgttcaac ctgattgaca cttttccctt gagaaaagaa     1260

gagatggtcc tacaagccga aatgagccag acctgtaaca cc                        1302


<210>  4321
<211>  1326
<212>  DNA
<213>  Homo Sapiens

<400>  4321
acttggtatg caggctctgg gtactacccg gacgagtctt acaatgaagt ttacgccgaa       60

gaggtgcccc aagctcccgc actggattac agagttcccc gttggtgtta tacgctgaac      120

atccaagatg gagaggccac atgctactct cccaagggtg gcaattatca ttcatctttg      180

gggactaggt gcgagctgag ctgtgataga ggttttcgtc ttataggaag gagatcagta      240

caatgtctgc catctaggag atggtccggt actgcctact gcagacagat gaggtgccac      300

gccttgcctt tcatcacaag cggaacttac acgtgcacta atggggtctt gctagactca      360

cgttgcgact attcttgttc cagcggctac cacttggaag gcgatagaag caggatttgc      420

atggaggacg gcagatggag tggaggggag cccgtttgcg tagatataga cccacccaaa      480

atcagatgcc ctcatagtag ggagaaaatg gcagagcctg aaaagctgac ggcgcgtgtt      540

tactgggatc cgccactagt aaaggattcc gccgacggga ccataacaag agtaacactt      600

aggggtccag agcctgggag tcatttccca gagggcgaac atgtaatcag atacacagcg      660

tatgacagag cgtataaccg tgcgagttgt aagtttatag tcaaagtaca ggttcgtaga      720

tgcccaactc taaagccgcc tcaacacggc tatcttacat gcacatctgc tggagacaat      780

tacggggcga catgtgaata ccactgcgat ggggggtacg atagacaagg aaccccgtcc      840

agagtatgcc agagctctag acagtggtcc ggaagtcccc caatttgcgc accgatgaag      900

atcaacgtca acgtgaacag tgcagccgga cttcttgatc aattttatga aaagcaaaga      960

ttgttgatca taagcgcacc tgacccgtca aacaggtatt ataaaatgca aatttctatg     1020

ctacagcaat ccacctgcgg tctagatctt aggcatgtca ctataatcga gctggtggga     1080

caaccgcctc aagaggtcgg aagaatcagg gaacaacagt tgagtgcaaa cataatcgaa     1140

gaactgaggc aattccaaag attaaccagg tcttatttta acatggtctt aattgacaaa     1200

caagggatcg acagagacag gtatatggaa ccagttactc cggaagaaat atttacattc     1260

attgacgact atttattaag caatcaggaa ctgacgcaga ggcgtgaaca aagagacatt     1320

tgtgag                                                                1326


<210>  4322
<211>  570
<212>  DNA
<213>  Homo Sapiens

<400>  4322
atgactggga ctttgcggac gcgcgcgtgg cctgccgcga agcgggctgc gggcctgcgc       60

tgggcgctac gggacgaggc tcgcctgagc gactgcttcc acctgggctg gggccagcac      120

aactgcggcc accacgagga cgcgggagcg ctctgcgcag gtgaggctga cagcgaaggc      180

ccagaggagc tgggactgca agtccagcag gatggttctg agaccacgcg ggtgcccact      240

cctcggccca gggacgggca tctacgtctg gtcaatggag cccaccgatg cgagggacgt      300

gtagagctct acctagggca acggtggggc actgtctgtg atgatgcttg ggacctgcgg      360

gcagccggtg tcctgtgccg ccagctgggc tgtggccagg ccctcgcagc ccctggcgag      420

gctcactttg gcccaggccg aggccccatt ctcctggaca atgtcaagtg ccgtggggaa      480

gaaagtgctc tgctgctctg ctctcatatc cgctgggatg cccacaactg tgaccacagc      540

gaggatgcca gtgtcctgtg ccagccttca                                       570


<210>  4323
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  4323
ctcagccata gtcacagtga gaaggcgaca ggaaccagct cgggggccaa ctctgaggag       60

tccactgcag cagagttttg ccgaattgac aagcccctgt gtcacagtga ggatgagaaa      120

ctcagcttcg aggcagtccg taacatccac aaactgatgg acgatgatgc caatggtgat      180

gtggatgtgg aagaaagtga tgagttcctg agggaagacc tcaattacca tgacccaaca      240

gtgaaacaca gcaccttcca tggtgaggat aagctcatca gcgtggagga cctgtggaag      300

gcatggaagt catcagaagt atacaattgg accgtggatg aggtggtaca gtggctgatc      360

acatatgtgg agctgcctca gtatgaggag accttccgga agctgcagct cagtggccat      420

gccatgccaa ggctggctgt caccaacacc accatgacag ggactgtgct gaagatgaca      480

gaccggagtc atcggcagaa gctgcagctg aaggctctgg atacagtgct ctttgggcct      540

cctctcttga ctcgccataa tcacctcaag gac                                   573


<210>  4324
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  4324
tgcgagcttg tgccccggca cctccgcggg cggcgggcga ctggctctgc cgcaactgcc       60

gcctcctctc ccgccgcggc ggccggcgat agcccggcgc tcatgacaga tccctgcatg      120

tcactgagtc caccatgctt tacagaagaa gacagattta gtctggaagc tcttcaaaca      180

atacataaac aaatggatga tgacaaagat ggtggaattg aagtagagga aagtgatgaa      240

ttcatcagag aagatatgaa atataaagat gctactaata aacacagcca tctgcacaga      300

gaagataaac atataacgat tgaggattta tggaaacgat ggaaaacatc agaagttcat      360

aattggaccc ttgaagacac tcttcagtgg ttgatagagt ttgttgaact accccaatat      420

gagaagaatt ttagagacaa caatgtcaaa ggaacgacac ttcccaggat agcagtgcac      480

gaaccttcat ttatgatctc ccagttgaaa atcagtgacc ggagtcacag acaaaaactt      540

cagctcaagg cattggatgt ggttttgttt ggacctctaa cacgcccacc tcataactgg      600

atgaaagatt tt                                                          612


<210>  4325
<211>  2184
<212>  DNA
<213>  Homo Sapiens

<400>  4325
gcgccgggcc ccgacggttt agacgtctgt gccacttgcc atgaacatgc cacatgccag       60

caaagagaag ggaagaagat ctgtatttgc aactatggat ttgtagggaa cgggaggact      120

cagtgtgttg ataaaaatga gtgccagttt ggagccactc ttgtctgtgg gaaccacaca      180

tcttgccaca acacccccgg gggcttctat tgcatttgcc tggaaggata tcgagccaca      240

aacaacaaca agacattcat tcccaacgat ggcacctttt gtacagacat agatgagtgt      300

gaagtttctg gcctgtgcag gcatggaggg cgatgcgtga acactcatgg gagctttgaa      360

tgctactgta tggatggata cttgccaagg aatggacctg aacctttcca cccgaccacc      420

gatgccacat catgcacaga aatagactgt ggtacccctc ctgaggttcc agatggctat      480

atcataggaa attatacgtc tagtctgggc agccaggttc gttatgcttg cagagaagga      540

ttcttcagtg ttccagaaga tacagtttca agctgcacag gcctgggcac atgggagtcc      600

ccaaaattac attgccaaga gatcaactgt ggcaaccctc cagaaatgcg gcacgccatc      660

ttggtaggaa atcacagctc caggctgggc ggtgtggctc gctatgtctg tcaagagggc      720

tttgagagcc ctggaggaaa gatcacttct gtttgcacag agaaaggcac ctggcgagaa      780

agtactttaa catgcacaga aattctgaca aagattaatg atgtatcact gtttaatgat      840

acctgtgtga gatggcaaat aaactcaaga agaataaacc ccaagatctc atatgtgata      900

tccataaaag gacaacggtt ggaccctatg gaatcagttc gtgaggagac agtcaacttg      960

accacagaca gcaggacccc agaagtgtgc ctagccctgt acccaggcac caactacacc     1020

gtgaacatct ccacagcacc tcccaggcgc tcgatgccag ccgtcatcgg tttccagaca     1080

gctgaagttg atctcttaga agatgatgga agtttcaata tttcaatatt taatgaaact     1140

tgtttgaaat tgaacaggcg ttctaggaaa gttggatcag aacacatgta ccaatttacc     1200

gttctgggtc agaggtggta tctggctaac ttttctcatg caacatcgtt taacttcaca     1260

acgagggaac aagtgcctgt agtgtgtttg gatctgtacc ctacgactga ttatacggtg     1320

aatgtgaccc tgctgagatc tcctaagcgg cactcagtgc aaataacaat agcaactccc     1380

ccagcagtaa aacagaccat cagtaacatt tcaggattta atgaaacctg cttgagatgg     1440

agaagcatca agacagctga tatggaggag atgtatttat tccaaatttg gggccagaga     1500

tggtatcaga aggaatttgc ccaggaaatg acctttaata tcagtagcag cagccgagat     1560

cccgaggtgt gcttggacct acgtccgggt accaactaca atgtcagtct ccgggctctg     1620

tcttcggaac ttcctgtggt catctccctg acaacccaga taacagagcc tcccctcccg     1680

gaagtagaat tttttacggt gcacagagga cctctaccac gcctcagact gaggaaagcc     1740

aaggagaaaa atggaccaat cagttcatat caggtgttag tgcttcccct ggccctccaa     1800

agcacatttt cttgtgattc tgaaggcgct tcctccttct ttagcaacgc ctctgatgct     1860

gatggatacg tggctgcaga actactggcc aaagatgttc cagatgatgc catggagata     1920

cctataggag acaggctgta ctatggggaa tattataatg cacccttgaa aagagggagt     1980

gattactgca ttatattacg aatcacaagt gaatggaata aggtgagaag acactcctgt     2040

gcagtttggg ctcaggtgaa agaaatacct tgtaactgta atttcctgag gctgcatatc     2100

cacagggcca actcagggga cacacagatt cgtcactcat gctgctgcag atggcgggtg     2160

ttggactggg ttccctggct gttg                                            2184


<210>  4326
<211>  2274
<212>  DNA
<213>  Homo Sapiens

<400>  4326
caagagagct gctccatgcg ctgtggcgcc ctggacgggc catgttcctg ccacccgacg       60

tgctctggcc ttggcacctg ctgcttggat ttccgggact tctgcctgga gatattgccc      120

tactcaggat ccatgatggg cggcaaggac tttgtggtgc ggcacttcaa gatgtccagc      180

cccacagacg ccagtgtgat ctgcaggttt aaggacagca tccagaccct cggccatgtg      240

gactcctccg ggcaagtgca ctgtgtgtca cctctgctct atgagagcgg ccgcatcccc      300

ttcactgtgt cactggacaa cggccactcc ttccctcgtg cgggcacctg gctggctgtg      360

caccccaaca aagtgtcaat gatggagaag agcgagttgg tgaacgagac gcgttggcaa      420

tactacggca ccgccaacac ctcaggcaac ctcagcctga cctggcatgt caagtcgctg      480

cccacgcaga ccatcaccat cgaactgtgg ggctacgagg agacaggaat gccctactca      540

caggagtgga ctgcaaagtg gtcgtacctg taccccctgg ccacacacat ccccaactcc      600

ggctctttca ctttcacccc aaaacctgct cctcccagct accagagatg gcgagtgggt      660

gcacttcgga tcatcgacag caaaaattac gcagggcaga aggacgtgca ggcgctctgg      720

accaacgacc acgcactggc ctggcacctg agcgatgact tccgagagga ccctgtggcc      780

tgggcacgaa ctcagtgcca ggcctgggag gagctggagg atcagctgcc caacttcctg      840

gaggagctgc cggactgccc ctgcaccctg acccaggccc gggctgactc cggccgcttc      900

ttcacggact acggctgtga catggagcag ggcagcgtgt gcacctacca ccccggggcc      960

gtgcactgtg tgcgttctgt gcaggccagc ctccggtacg gctcaggtca gcagtgctgc     1020

tacacagcgg acgggacgca gctcctgaca gctgactcca gcggcggcag cactcccgac     1080

cgcggccatg actggggcgc acccccgttc cgcacgccac cccgagtgcc cagcatgtcc     1140

cactggctct acgatgtcct cagcttctat tactgctgcc tctgggcacc cgactgcccc     1200

cgctacatgc aacggcggcc ctccaatgac tgccgcaact accggccccc aagactggcc     1260

tccgccttcg gagacccaca ctttgtgacc ttcgacggca ccaacttcac attcaatggg     1320

cgcggagagt acgtgctgct ggaggcagcg ctgaccgacc tgagggtgca ggcgcgggcc     1380

cagcccggga cgatgtccaa cggcacggag acccgtggca ctgggctgac cgcagtggcc     1440

gtccaggagg gcaactcaga tgtggtggaa gtcaggctgg ccaacaggac cggaggtctg     1500

gaggtgctgc tgaaccagga ggtgctgagc ttcaccgagc agagctggat ggacctgaaa     1560

ggaatgttcc tgtcggtggc tgccggggac agggtctcca tcatgctggc atcaggggcc     1620

ggcctggagg tcagcgtgca gggcccgttc ctgagtgtgt ccgtcctgct gcctgagaag     1680

ttcctcaccc acacccacgg cctcctcggg acactcaaca acgaccccac cgacgacttc     1740

accctgcaca gcgggcgcgt cctgccccca ggcaccagtc cccaggagct gttcctgttt     1800

ggggccaact ggaccgtgca caatgcgtcc tccctgctca cctacgattc ctggttcctg     1860

gtccacaact tcctgtacca acccaagcac gaccccacct tcgagcccct cttccccagt     1920

gagaccaccc tcaaccccag cctggcacaa gaggcagcca aactatgtgg ggacgatcat     1980

ttctgcaact ttgatgtggc agccactggg agcctgagca cgggcactgc cactcgggtg     2040

gcccaccagc tgcaccagcg tcgcatgcag agcctgcagc cagtggtgtc ctgtggctgg     2100

ctggccccac ctcccaacgg acaaaaggag ggcaacaggt acctggcggg ttccaccatc     2160

tacttccact gtgacaacgg ctacagcctg gccggggcag agaccagcac ctgccaggct     2220

gacggcacct ggtcctcacc caccccgaag tgccagccag gacgcagcta cgcg           2274


<210>  4327
<211>  747
<212>  DNA
<213>  Homo Sapiens

<400>  4327
ttcggccctg cacagctcac gggcgggttc gatgaccttc aagtgtgtgc tgaccccggc       60

attcccgaga atggcttcag gacccccagc ggaggggttt tctttgaagg ctctgtagcc      120

cgatttcact gccaagacgg attcaagctg aagggcgcta caaagagact gtgtttgaag      180

cattttaatg gaaccctagg ctggatccca agtgataatt ccatctgtgt gcaagaagat      240

tgccgtatcc ctcaaatcga agatgctgag attcataaca agacatatag acatggagag      300

aagctaatca tcacttgtca tgaaggattc aagatccggt accccgacct acacaatatg      360

gtttcattat gtcgcgatga tggaacgtgg aataatctgc ccatctgtca aggctgcctg      420

agacctctag cctcttctaa tggctatgta aacatctctg agctccagac ctccttcccg      480

gtggggactg tgatctccta tcgctgcttt cccggattta aacttgatgg gtctgcgtat      540

cttgagtgct tacaaaacct tatctggtcg tccagcccac cccggtgcct tgctctggaa      600

ggaggaagac ctgaacatct tttccctgtc ctttatttcc cacacatcag gttggcagct      660

gctgtgcttt atttttgccc tgtgttaaag tcctctccca ccccagcacc tacctgttcc      720

tcaactagca ccaccacatc tctgttc                                          747


<210>  4328
<211>  123
<212>  DNA
<213>  Homo Sapiens

<400>  4328
gatggtggag aggaacagac actcagcact gaagcagaga cctgggaagg cgctggcccc       60

agcattcagc tccagctgca ggaggtgaag acgggcaagg caagccagtt ctttgggctg      120

atg                                                                    123


<210>  4329
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  4329
caaggagata caagggggga cggcagtttg cccaaaccca gtctttccgc ttggcccagt       60

agcgtggtcc ccgcaaacag taatgtgacc ctgagatgct ggacgccagc ccgtggagtt      120

agtttcgtct tgaggaaagg ggggattatt ctggagagtc ctaagcctct ggactctacc      180

gaaggggcgg cggaatttca cctaaacaac ctgaaagtaa ggaacgcggg agaatataca      240

tgcgagtact accgtaaagc ctcaccccac attttgagcc agagaagcga tgtcctgttg      300

ctactagtta ccggtcactt atctaaaccc ttccttagga cctaccaacg tggtactgtg      360

acggcagggg gaagggtgac acttcaatgc cagaagaggg accagctatt cgttcccatt      420

atgtttgcgc tgcttaaagc aggtactccc agcccaatac agttacagag tcccgctggt      480

aaagagatcg acttctcttt agtagacgtt accgccggag acgctggaaa ctacagttgt      540

atgtattatc agacgaagtc ccctttctgg gcctctgaac ccagtgatca gttagagata      600

ttggtgacag ttccaccagg cacaacgagc tcaaactact ctcttggaaa tttcgtaagg      660


<210>  4330
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  4330
ctgggccatc aggaatttgc tcgtccatct cggggatacc tggccttcag agatgacagc       60

atttggcccc aggaggagcc tgcaattcgg cctcggtctt cccagcgtgt gccgcccatg      120

gggatacagc acagtaagga gctaaacaga acctgctgcc tgaatggggg aacctgcatg      180

ctggggtcct tttgtgcctg ccctccctcc ttctacggac ggaactgtga gcacgatgtg      240

cgcaaagaga attgtgggtc tgtgccccat gacacctggc tgcccaagaa gtgttccctg      300

tgtaaatgct ggcacggtca gctccgctgc tttcctcagg catttctacc cggctgtgat      360


<210>  4331
<211>  2175
<212>  DNA
<213>  Homo Sapiens

<400>  4331
atggacttga tcttgatcaa ttccctacct cttgtatctg atgctgaaac atctctcacc       60

tgcattgcct ctgggtggcg cccccatgag cccatcacca taggaaggga ctttgaagcc      120

ttaatgaacc agcaccagga tccgctggaa gttactcaag atgtgaccag agaatgggct      180

aaaaaagttg tttggaagag agaaaaggct agtaagatca atggtgctta tttctgtgaa      240

gggcgagttc gaggagaggc aatcaggata cgaaccatga agatgcgtca acaagcttcc      300

ttcctaccag ctactttaac tatgactgtg gacaagggag ataacgtgaa catatctttc      360

aaaaaggtat tgattaaaga agaagatgca gtgatttaca aaaatggttc cttcatccat      420

tcagtgcccc ggcatgaagt acctgatatt ctagaagtac acctgcctca tgctcagccc      480

caggatgctg gagtgtactc ggccaggtat ataggaggaa acctcttcac ctcggccttc      540

accaggctga tagtccggag atgtgaagcc cagaagtggg gacctgaatg caaccatctc      600

tgtactgctt gtatgaacaa tggtgtctgc catgaagata ctggagaatg catttgccct      660

cctgggttta tgggaaggac gtgtgagaag gcttgtgaac tgcacacgtt tggcagaact      720

tgtaaagaaa ggtgcagtgg acaagaggga tgcaagtctt atgtgttctg tctccctgac      780

ccctatgggt gttcctgtgc cacaggctgg aagggtctgc agtgcaatga agcatgccac      840

cctggttttt acgggccaga ttgtaagctt aggtgcagct gcaacaatgg ggagatgtgt      900

gatcgcttcc aaggatgtct ctgctctcca ggatggcagg ggctccagtg tgagagagaa      960

ggcataccga ggatgacccc aaagatagtg gatttgccag atcatataga agtaaacagt     1020

ggtaaattta atcccatttg caaagcttct ggctggccgc tacctactaa tgaagaaatg     1080

accctggtga agccggatgg gacagtgctc catccaaaag actttaacca tacggatcat     1140

ttctcagtag ccatattcac catccaccgg atcctccccc ctgactcagg agtttgggtc     1200

tgcagtgtga acacagtggc tgggatggtg gaaaagccct tcaacatttc tgttaaagtt     1260

cttccaaagc ccctgaatgc cccaaacgtg attgacactg gacataactt tgctgtcatc     1320

aacatcagct ctgagcctta ctttggggat ggaccaatca aatccaagaa gcttctatac     1380

aaacccgtta atcactatga ggcttggcaa catattcaag tgacaaatga gattgttaca     1440

ctcaactatt tggaacctcg gacagaatat gaactctgtg tgcaactggt ccgtcgtgga     1500

gagggtgggg aagggcatcc tggacctgtg agacgcttca caacagcttc tatcggactc     1560

cctcctccaa gaggtctaaa tctcctgcct aaaagtcaga ccactctaaa tttgacctgg     1620

caaccaatat ttccaagctc ggaagatgac ttttatgttg aagtggagag aaggtctgtg     1680

caaaaaagtg atcagcagaa tattaaagtt ccaggcaact tgacttcggt gctacttaac     1740

aacttacatc ccagggagca gtacgtggtc cgagctagag tcaacaccaa ggcccagggg     1800

gaatggagtg aagatctcac tgcttggacc cttagtgaca ttcttcctcc tcaaccagaa     1860

aacatcaaga tttccaacat tacacactcc tcggctgtga tttcttggac aatattggat     1920

ggctattcta tttcttctat tactatccgt tacaaggttc aaggcaagaa tgaagaccag     1980

cacgttgatg tgaagataaa gaatgccacc atcactcagt atcagctcaa gggcctagag     2040

cctgaaacag cataccaggt ggacattttt gcagagaaca acatagggtc aagcaaccca     2100

gccttttctc atgaactggt gaccctccca gaatctcaag caccagcgga cctcggaggg     2160

gggaagatgc tgctt                                                      2175


<210>  4332
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  4332
attctggaga atggtgtcaa tgtcactgtg tcccagatga cttctgtgtt gaatgggagg       60

actagacggt ttgcagatat tcagctccag catggagccc tgtgcttcaa catccggtat      120

gggacaactg tcgaagagga aaagaatcac gtgttggaga ttgccagaca gcgcgcagtg      180

gcccaggcct ggactaagga acaaagaagg ctgcaagagg gggaagaggg gattagggca      240

tggacagaag gggaaaagca gcagcttttg agcactgggc gggtacaagg ttacgatggg      300

tattttgttt tgtctgttga gcagtattta gaactttctg acagtgccaa taatattcac      360

tttatgagac agagcgaaat aggcaggagg                                       390


<210>  4333
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  4333
ctgtattgtc aaaagggtct gtccatgact gtggaagcag atccagccaa tatgtttaac       60

tggaccacag aggaagtgga gacttgtgac aaaggggcac tttgccagga aaccatacta      120

ataattaaag cagggactga gacagccatt ttggccacga agggctgcat cccggaaggg      180

gaggaggcca taacaattgt ccagcactct tcacctcccg gcctgatcgt gacctcctac      240

agtaactact gtgaggattc cttctgtaat gacaaagaca gcctgtctca gttttgggag      300

ttcagtgaga ccacagcttc cactgtgtca acaaccctcc attgtccaac ctgtgtggct      360

ttggggacct gtttcagtgc tccttctctt ccctgtccca atggtacaac tcgatgctat      420

caaggaaaac ttgagatcac tggaggtggc attgagtcgt ctgtggaggt caaaggctgt      480

acagccatga ttggctgcag gctgatgtct ggaatcttag cagtaggacc catgtttgtg      540

agggaagcgt gcccacatca gctgctcact caacctcgaa agactgaaaa t               591


<210>  4334
<211>  2037
<212>  DNA
<213>  Homo Sapiens

<400>  4334
gtccctgata aaactgtgag atggtgtgca gtgtcggagc atgaggccac taagtgccag       60

agtttccgcg accatatgaa aagcgtcatt ccatccgatg gtcccagtgt tgcttgtgtg      120

aagaaagcct cctaccttga ttgcatcagg gccattgcgg caaacgaagc ggatgctgtg      180

acactggatg caggtttggt gtatgatgct tacctggctc ccaataacct gaagcctgtg      240

gtggcagagt tctatgggtc aaaagaggat ccacagactt tctattatgc tgttgctgtg      300

gtgaagaagg atagtggctt ccagatgaac cagcttcgag gcaagaagtc ctgccacacg      360

ggtctaggca ggtccgctgg gtggaacatc cccataggct tactttactg tgacttacct      420

gagccacgta aacctcttga gaaagcagtg gccaatttct tctcgggcag ctgtgcccct      480

tgtgcggatg ggacggactt cccccagctg tgtcaactgt gtccagggtg tggctgctcc      540

acccttaacc aatacttcgg ctactcagga gccttcaagt gtctgaagaa tggtgctggg      600

gatgtggcct ttgtcaagca ctcgactata tttgagaact tggcaaacaa ggctgacagg      660

gaccagtatg agctgctttg cctggacaac acccggaagc cggtagatga atacaaggac      720

tgccacttgg cccaggtccc ttctcatacc gtcgtggccc gaagtatggg cggcaaggag      780

gacttgatct gggagcttct caaccaggcc caggaacatt ttggcaaaga caaatcaaaa      840

gaattccaac tattcagctc tcctcatggg aaggacctgc tgtttaagga ctctgcccac      900

gggtttttaa aagtcccccc caggatggat gccaagatgt acctgggcta tgagtatgtc      960

actgccatcc ggaatctacg ggaaggcaca tgccaagaag ccccaacaga tgaatgcaag     1020

cctgtgaagt ggtgtgcgct gagccaccac gagaggctca agtgtgatga gtggagtgtt     1080

aacagtgtag ggaaaataga gtgtgtatca gcagagacca ccgaagactg catcgccaag     1140

atcatgaatg gagaagctga tgccatgagc ttggatggag ggtttgtcta catagcgggc     1200

aagtgtggtc tggtgcctgt cttggcagaa aactacaata agagcgataa ttgtgaggat     1260

acaccagagg cagggtattt tgctgtagca gtggtgaaga aatcagcttc tgacctcacc     1320

tgggacaatc tgaaaggcaa gaagtcctgc catacggcag ttggcagaac cgctggctgg     1380

aacatcccca tgggcctgct ctacaataag atcaaccact gcagatttga tgaatttttc     1440

agtgaaggtt gtgcccctgg gtctaagaaa gactccagtc tctgtaagct gtgtatgggc     1500

tcaggcctaa acctgtgtga acccaacaac aaagagggat actacggcta cacaggcgct     1560

ttcaggtgtc tggttgagaa gggagatgtg gcctttgtga aacaccagac tgtcccacag     1620

aacactgggg gaaaaaaccc tgatccatgg gctaagaatc tgaatgaaaa agactatgag     1680

ttgctgtgcc ttgatggtac caggaaacct gtggaggagt atgcgaactg ccacctggcc     1740

agagccccga atcacgctgt ggtcacacgg aaagataagg aagcttgcgt ccacaagata     1800

ttacgtcaac agcagcacct atttggaagc aacgtaactg actgctcggg caacttttgt     1860

ttgttccggt cggaaaccaa ggaccttctg ttcagagatg acacagtatg tttggccaaa     1920

cttcatgaca gaaacacata tgaaaaatac ttaggagaag aatatgtcaa ggctgttggt     1980

aacctgagaa aatgctccac ctcatcactc ctggaagcct gcactttccg tagacct        2037


<210>  4335
<211>  2091
<212>  DNA
<213>  Homo Sapiens

<400>  4335
cgagggtcct gccaggcgtg cggagactct gtgttggtgg tcagtgagga tgtcaactat       60

gagcctgacc tggatttcca ccagggcaga ctctactgga gcgacctcca ggccatgttc      120

ctgcagttcc tgggggaggg gcgcctggag gacaccatca ggcaaaccag ccttcgggaa      180

cgggtggcag gctcggccgg gatggccgct ctgactcagg acattcgcgc ggcgctctcc      240

cgccagaagc tggaccacgt gtggaccgac acgcactacg tggggctgca attcccggat      300

ccggctcacc ccaacaccct gcactgggtc gatgaggccg ggaaggtcgg agagcagctg      360

ccgctggagg accctgacgt ctactgcccc tacagcgcca tcggcaacgt cacgggagag      420

ctggtgtacg cccactacgg gcggcccgaa gacctgcagg acctgcgggc caggggcgtg      480

gatccagtgg gccgcctgct gctggtgcgc gtgggggtga tcagcttcgc ccagaaggtg      540

accaatgctc aggacttcgg ggctcaagga gtgctcatat acccagagcc agcggacttc      600

tcccaggacc cacccaagcc aagcctgtcc agccagcagg cagtgtatgg acatgtgcac      660

ctgggaactg gagaccccta cacacctggc ttcccttcct tcaatcaaac ccagttccct      720

ccagttgcat catcaggcct tcccagcatc ccagcccagc ccatcagtgc agacattgcc      780

tcccgcctgc tgaggaagct caaaggccct gtggcccccc aagaatggca ggggagcctc      840

ctaggctccc cttatcacct gggccccggg ccacgacttc ggctagtggt caacaatcac      900

aggacctcca cccccatcaa caacatcttc ggctgcatcg aaggccgctc agagccagat      960

cactacgttg tcatcggggc ccagagggat gcatggggcc caggagcagc taaatccgct     1020

gtggggacgg ctatactcct ggagctggtg cggacctttt cctccatggt gagcaacggc     1080

ttccggcccc gcagaagtct cctcttcatc agctgggacg gtggtgactt tggaagcgtg     1140

ggctccacgg agtggctaga gggctacctc agcgtgctgc acctcaaagc cgtagtgtac     1200

gtgagcctgg acaacgcagt gctgggggat gacaagtttc atgccaagac cagccccctt     1260

ctgacaagtc tcattgagag tgtcctgaag caggtggatt ctcccaacca cagtgggcag     1320

actctctatg aacaggtggt gttcaccaat cccagctggg atgctgaggt gatccggccc     1380

ctacccatgg acagcagtgc ctattccttc acggcctttg tgggagtccc tgccgtcgag     1440

ttctccttta tggaggacga ccaggcctac ccattcctgc acacaaagga ggacacttat     1500

gagaacctgc ataaggtgct gcaaggccgc ctgcccgccg tggcccaggc cgtggcccag     1560

ctcgcagggc agctcctcat ccggctcagc cacgatcgcc tgctgcccct cgacttcggc     1620

cgctacgggg acgtcgtcct caggcacatc gggaacctca acgagttctc tggggacctc     1680

aaggcccgcg ggctgaccct gcagtgggtg tactcggcgc ggggggacta catccgggcg     1740

gcggaaaagc tgcggcagga gatctacagc tcggaggaga gagacgagcg actgacacgc     1800

atgtacaacg tgcgcataat gcgggtggag ttctacttcc tttcccagta cgtgtcgcca     1860

gccgactccc cgttccgcca catcttcatg ggccgtggag accacacgct gggcgccctg     1920

ctggaccacc tgcggctgct gcgctccaac agctccggga cccccggggc cacctcctcc     1980

actggcttcc aggagagccg tttccggcgt cagctagccc tgctcacctg gacgctgcaa     2040

ggggcagcca atgcgcttag cggggatgtc tggaacattg ataacaactt c              2091


<210>  4336
<211>  2016
<212>  DNA
<213>  Homo Sapiens

<400>  4336
tgtaaagggg tagaaccaaa aactgagtgt gagagactgg caggaaccga gtctccagtg       60

agggaggagc caggagagga cttccctgca gcacgtcgct tatattggga tgacctgaag      120

agaaagttgt cggagaaact ggacagcaca gacttcaccg gcaccatcaa gctgctgaat      180

gaaaattcat atgtccctcg tgaggctgga tctcaaaaag atgaaaatct tgcgttgtat      240

gttgaaaatc aatttcgtga atttaaactc agcaaagtct ggcgtgatca acattttgtt      300

aagattcagg tcaaagacag cgctcaaaac tcggtgatca tagttgataa gaacggtaga      360

cttgtttacc tggtggagaa tcctgggggt tatgtggcgt atagtaaggc tgcaacagtt      420

actggtaaac tggtccatgc taattttggt actaaaaaag attttgagga tttatacact      480

cctgtgaatg gatctatagt gattgtcaga gcagggaaaa tcacctttgc agaaaaggtt      540

gcaaatgctg aaagcttaaa tgcaattggt gtgttgatat acatggacca gactaaattt      600

cccattgtta acgcagaact ttcattcttt ggacatgctc atctggggac aggtgaccct      660

tacacacctg gattcccttc cttcaatcac actcagtttc caccatctcg gtcatcagga      720

ttgcctaata tacctgtcca gacaatctcc agagctgctg cagaaaagct gtttgggaat      780

atggaaggag actgtccctc tgactggaaa acagactcta catgtaggat ggtaacctca      840

gaaagcaaga atgtgaagct cactgtgagc aatgtgctga aagagataaa aattcttaac      900

atctttggag ttattaaagg ctttgtagaa ccagatcact atgttgtagt tggggcccag      960

agagatgcat ggggccctgg agctgcaaaa tccggtgtag gcacagctct cctattgaaa     1020

cttgcccaga tgttctcaga tatggtctta aaagatgggt ttcagcccag cagaagcatt     1080

atctttgcca gttggagtgc tggagacttt ggatcggttg gtgccactga atggctagag     1140

ggataccttt cgtccctgca tttaaaggct ttcacttata ttaatctgga taaagcggtt     1200

cttggtacca gcaacttcaa ggtttctgcc agcccactgt tgtatacgct tattgagaaa     1260

acaatgcaaa atgtgaagca tccggttact gggcaatttc tatatcagga cagcaactgg     1320

gccagcaaag ttgagaaact cactttagac aatgctgctt tccctttcct tgcatattct     1380

ggaatcccag cagtttcttt ctgtttttgc gaggacacag attatcctta tttgggtacc     1440

accatggaca cctataagga actgattgag aggattcctg agttgaacaa agtggcacga     1500

gcagctgcag aggtcgctgg tcagttcgtg attaaactaa cccatgatgt tgaattgaac     1560

ctggactatg agaggtacaa cagccaactg ctttcatttg tgagggatct gaaccaatac     1620

agagcagaca taaaggaaat gggcctgagt ttacagtggc tgtattctgc tcgtggagac     1680

ttcttccgtg ctacttccag actaacaaca gatttcggga atgctgagaa aacagacaga     1740

tttgtcatga agaaactcaa tgatcgtgtc atgagagtgg agtatcactt cctctctccc     1800

tacgtatctc caaaagagtc tcctttccga catgtcttct ggggctccgg ctctcacacg     1860

ctgccagctt tactggagaa cttgaaactg cgtaaacaaa ataacggtgc ttttaatgaa     1920

acgctgttca gaaaccagtt ggctctagct acttggacta ttcagggagc tgcaaatgcc     1980

ctctctggtg acgtttggga cattgacaat gagttt                               2016


<210>  4337
<211>  150
<212>  DNA
<213>  Homo Sapiens

<400>  4337
gtggtgtccc attttaatga ctgcccagat tcccacactc agttctgctt ccatggaacc       60

tgcaggtttt tggtgcagga ggacaagcca gcatgtgtct gccattctgg gtacgttggt      120

gcacgctgtg agcatgcgga cctcctggcc                                       150


<210>  4338
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  4338
gccctggaca ccaactattg cttcagctcc acggagaaga actgctgcgt gcggcagctg       60

tacattgact tccgcaagga cctcggctgg aagtggatcc acgagcccaa gggctaccat      120

gccaacttct gcctcgggcc ctgcccctac atttggagcc tggacacgca gtacagcaag      180

gtcctggccc tgtacaacca gcataacccg ggcgcctcgg cggcgccgtg ctgcgtgccg      240

caggcgctgg agccgctgcc catcgtgtac tacgtgggcc gcaagcccaa ggtggagcag      300

ctgtccaaca tgatcgtgcg ctcctgcaag tgcagc                                336


<210>  4339
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  4339
gctttggatg cggcctattg ctttagaaat gtgcaggata attgctgcct acgtccactt       60

tacattgatt tcaagaggga tctagggtgg aaatggatac acgaacccaa agggtacaat      120

gccaacttct gtgctggagc atgcccgtat ttatggagtt cagacactca gcacagcagg      180

gtcctgagct tatataatac cataaatcca gaagcatctg cttctccttg ctgcgtgtcc      240

caagatttag aacctctaac cattctctac tacattggca aaacacccaa gattgaacag      300

ctttctaata tgattgtaaa gtcttgcaaa tgcagc                                336


<210>  4340
<211>  831
<212>  DNA
<213>  Homo Sapiens

<400>  4340
ctgtccactt gcaccacctt ggacttcggc cacatcaaga agaagagggt ggaagccatt       60

aggggacaga tcttgagcaa gctcaggctc accagccccc ctgagccaac ggtgatgacc      120

cacgtcccct atcaggtcct ggccctttac aacagcaccc gggagctgct ggaggagatg      180

catggggaga gggaggaagg ctgcacccag gaaaacaccg agtcggaata ctatgccaaa      240

gaaatccata aattcgacat gatccagggg ctggcggagc acaacgaact ggctgtctgc      300

cctaaaggaa ttacctccaa ggttttccgc ttcaatgtgt cctcagtgga gaaaaataga      360

accaacctat tccgagcaga attccgggtc ttgcgggtgc ccaaccccag ctctaagcgg      420

aatgagcaga ggatcgagct cttccagatc cttcggccag atgagcacat tgccaaacag      480

cgctatatcg gtggcaagaa tctgcccaca cggggcactg ccgagtggct gtcctttgat      540

gtcactgaca ctgtgcgtga gtggctgttg agaagagagt ccaacttagg tctagaaatc      600

agcattcact gtccatgtca cacctttcag cccaatggag atatcctgga aaacattcac      660

gaggtgatgg aaatcaaatt caaaggcgtg gacaatgagg atgaccatgg ccgtggagat      720

ctggggcgcc tcaagaagca gaaggatcac cacaaccctc atctaatcct catgatgatt      780

cccccacacc ggctcgacaa cccgggccag gggggtcaga ggaagaagcg g               831


<210>  4341
<211>  1980
<212>  DNA
<213>  Homo Sapiens

<400>  4341
ggtcccgcca agtcgcccta ccagctggtg ctgcagcaca gcaggctccg gggccgccag       60

cacggcccca acgtgtgtgc tgtgcagaag gttattggca ctaataggaa gtacttcacc      120

aactgcaagc agtggtacca aaggaaaatc tgtggcaaat caacagtcat cagctacgag      180

tgctgtcctg gatatgaaaa ggtccctggg gagaagggct gtccagcagc cctaccactc      240

tcaaaccttt acgagaccct gggagtcgtt ggatccacca ccactcagct gtacacggac      300

cgcacggaga agctgaggcc tgagatggag gggcccggca gcttcaccat cttcgcccct      360

agcaacgagg cctgggcctc cttgccagct gaagtgctgg actccctggt cagcaatgtc      420

aacattgagc tgctcaatgc cctccgctac catatggtgg gcaggcgagt cctgactgat      480

gagctgaaac acggcatgac cctcacctct atgtaccaga attccaacat ccagatccac      540

cactatccta atgggattgt aactgtgaac tgtgcccggc tgctgaaagc cgaccaccat      600

gcaaccaacg gggtggtgca cctcatcgat aaggtcatct ccaccatcac caacaacatc      660

cagcagatca ttgagatcga ggacaccttt gagacccttc gggctgctgt ggctgcatca      720

gggctcaaca cgatgcttga aggtaacggc cagtacacgc ttttggcccc gaccaatgag      780

gccttcgaga agatccctag tgagactttg aaccgtatcc tgggcgaccc agaagccctg      840

agagacctgc tgaacaacca catcttgaag tcagctatgt gtgctgaagc catcgttgcg      900

gggctgtctg tggagaccct ggagggcacg acactggagg tgggctgcag cggggacatg      960

ctcactatca acgggaaggc gatcatctcc aataaagaca tcctagccac caacggggtg     1020

atccactaca ttgatgagct actcatccca gactcagcca agacactatt tgaattggct     1080

gcagagtctg atgtgtccac agccattgac cttttcagac aagccggcct cggcaatcat     1140

ctctctggaa gtgagcggtt gaccctcctg gctcccctga attctgtatt caaagatgga     1200

acccctccaa ttgatgccca tacaaggaat ttgcttcgga accacataat taaagaccag     1260

ctggcctcta agtatctgta ccatggacag accctggaaa ctctgggcgg caaaaaactg     1320

agagtttttg tttatcgtaa tagcctttgc attgagaaca gctgcatcgc ggcccacgac     1380

aagaggggga ggtacgggac cctgttcacg atggaccggg tgctgacccc cccaatgggg     1440

actgtcatgg atgtcctgaa gggagacaat cgctttagca tgctggtagc tgccatccag     1500

tctgcaggac tgacggagac cctcaaccgg gaaggagtct acacagtctt cgctcccaca     1560

aatgaagcct tccgagccct gccaccaaga gaacggagca gactcttggg agatgccaag     1620

gaacttgcca acatcctgaa ataccacatt ggtgatgaaa tcctggttag cggaggcatc     1680

ggggccctgg tgcggctaaa gtctctccaa ggtgacaagc tggaagtcag cttgaaaaac     1740

aatgtggtga gtgtcaacaa ggagcctgtt gccgagcctg acatcatggc cacaaatggc     1800

gtggtccatg tcatcaccaa tgttctgcag cctccagcca acagacctca ggaaagaggg     1860

gatgaacttg cagactctgc gcttgagatc ttcaaacaag catcagcgtt ttccagggct     1920

tcccagaggt ctgtgcgact agcccctgtc tatcaaaagt tattagagag gatgaagcat     1980


<210>  4342
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  4342
ctacaatgct tctgccactt atgtaccaaa gacaacttca catgcgttac ggatggactg       60

tgttttgttt cagtcactga gaccaccgac aaagttatcc ataattcaat gtgtatcgcg      120

gagattgacc taatccccag ggacagaccg tttgtctgtg cgccttcttc aaaaaccggc      180

tctgtaacaa ctacctactg ctgcaatcaa gaccattgta ataaaatcga gcttcccacc      240

acggttaaga gctcaccggg gctggggcca gtggaactg                             279


<210>  4343
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  4343
acgatcccac cgcacgttca gaagtcggat gtggaaatgg aggcccagaa agatgaaatc       60

atctgcccca gctgtaatag gactgcccat ccactgagac atattaataa cgacatgata      120

gtcactgaca acaacggtgc agtcaagttt ccacaactgt gtaaattttg tgatgtgaga      180

ttttccacct gtgacaacca gaaatcctgc atgagcaact gcagcatcac ctccatctgt      240

gagaagccac aggaagtctg tgtggctgta tggagaaaga atgacgagaa cataacacta      300

gagacagttt gccatgaccc caagctcccc taccatgact ttattctgga agatgctgct      360

tctccaaagt gcattatgaa ggaaaaaaaa aagcctggtg agactttctt catgtgttcc      420

tgtagctctg atgagtgcaa tgacaacatc atcttctcag aagaatataa caccagcaat      480

cctgacttgt tgctagtcat atttcaa                                          507


<210>  4344
<211>  2301
<212>  DNA
<213>  Homo Sapiens

<400>  4344
ggtccagagc ctggtgcact gtgtgaactg tcacctgtca gtgcctccca tcctgtccag       60

gccttgatgg agagcttcac tgttttgtca ggctgtgcca gcagaggcac aactgggctg      120

ccacaggagg tgcatgtcct gaatctccgc actgcgggcc aggggcctgg ccagctacag      180

agagaggtca cacttcacct gaatcccatc tcctcagtcc acatccacca caagtctgtt      240

gtgttcctgc tcaactcccc acaccccctg gtgtggcatc tgaagacaga gagacttgcc      300

actggggtct ccagactgtt tttggtgtct gagggttctg tggtccagtt ttcatcagca      360

aacttctcct tgacagcaga aacagaagaa aggaacttcc cccatggaaa tgaacatctg      420

ttaaattggg cccgaaaaga gtatggagca gttacttcat tcaccgaact caagatagca      480

agaaacattt atattaaagt gggggaagat caagtgttcc ctccaaagtg caacataggg      540

aagaattttc tctcactcaa ttaccttgct gagtaccttc aacccaaagc agcagaaggg      600

tgtgtgatgt ccagccagcc ccagaatgag gaagtacaca tcatcgagct aatcaccccc      660

aactctaacc cctacagtgc tttccaggtg gatataacaa ttgatataag accttctcaa      720

gaggatcttg aagtggtcaa aaatctcatc ctgatcttga agtgcaaaaa gtctgtcaac      780

tgggtgatca aatcttttga tgttaaggga agcctgaaaa ttattgctcc taacagtatt      840

ggctttggaa aagagagtga aagatctatg acaatgacca aatcaataag agatgacatt      900

ccttcaaccc aagggaatct ggtgaagtgg gctttggaca atggctatag tccaataact      960

tcatacacaa tggctcctgt ggctaataga tttcatcttc ggcttgaaaa taatgcagag     1020

gagatgggag atgaggaagt ccacactatt cctcctgagc tacggatcct gctggaccct     1080

ggtgccctgc ctgccctgca gaacccgccc atccggggag gggaaggcca aaatggaggc     1140

cttccgtttc ctttcccaga tatttccagg agagtctgga atgaagaggg agaagatggg     1200

ctccctcggc caaaggaccc tgtcattccc agcatacaac tgtttcctgg tctcagagag     1260

ccagaagagg tgcaagggag cgtggatatt gccctgtctg tcaaatgtga caatgagaag     1320

atgatcgtgg ctgtagaaaa agattctttt caggccagtg gctactcggg gatggacgtc     1380

accctgttgg atcctacctg caaggccaag atgaatggca cacactttgt tttggagtct     1440

cctctgaatg gctgcggtac tcggccccgg tggtcagccc ttgatggtgt ggtctactat     1500

aactccattg tgatacaggt tccagccctt ggggacagta gtggttggcc agatggttat     1560

gaagatctgg agtcaggtga taatggattt ccgggagata tggatgaagg agatgcttcc     1620

ctgttcaccc gacctgaaat cgtggtgttt aattgcagcc ttcagcaggt gaggaacccc     1680

agcagcttcc aggaacagcc ccacggaaac atcaccttca acatggagct atacaacact     1740

gacctctttt tggtgccctc ccagggcgtc ttctctgtgc cagagaatgg acacgtttat     1800

gttgaggtat ctgttactaa ggctgaacaa gaactgggat ttgccatcca aacgtgcttt     1860

atctctccat attcgaaccc tgataggatg tctcattaca ccattattga gaatatttgt     1920

cctaaagatg aatctgtgaa attctacagt cccaagagag tgcactttcc tatcccgcaa     1980

gctgacatgg ataagaagcg attcagcttt gtcttcaagc ctgtcttcaa cacctcactg     2040

ctctttctac agtgtgagct gacgctgtgt acgaagatgg agaagcaccc ccagaagttg     2100

cctaagtgtg tgcctcctga cgaagcctgc acctcgctgg acgcctcgat aatctgggcc     2160

atgatgcaga ataagaagac gttcaccaag ccccttgctg tgatccacca tgaagcagaa     2220

tctaaagaaa aaggtccaag catgaaggaa ccaaatccaa tttctccacc aattttccat     2280

ggtctggaca ccctaaccgt g                                               2301


<210>  4345
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  4345
gcacccgcag agccgcagcc gggtggcagc cagtgcgtcg agcacgactg cttcgcgctc       60

tacccgggcc ccgcgacctt cctcaatgcc agtcagatct gcgacggact gcggggccac      120

ctaatgacag tgcgctcctc ggtggctgcc gatgtcattt ccttgctact gaacggcgac      180

ggcggcgttg gccgccggcg cctctggatc ggcctgcagc tgccacccgg ctgcggcgac      240

cccaagcgcc tcgggcccct gcgcggcttc cagtgggtta cgggagacaa caacaccagc      300

tatagcaggt gggcacggct cgacctcaat ggggctcccc tctgcggccc gttgtgcgtc      360

gctgtctccg ctgctgaggc cactgtgccc agcgagccga tctgggagga gcagcagtgc      420

gaagtgaagg ccgatggctt cctctgcgag ttccacttcc cagccacctg caggccactg      480

gctgtggagc ccggcgccgc ggctgccgcc gtctcgatca cctacggcac cccgttcgcg      540

gcccgcggag cggacttcca ggcgctgccg gtgggcagct ccgccgcggt ggctcccctc      600

ggcttacagc taatgtgcac cgcgccgccc ggagcggtcc aggggcactg ggccagggag      660

gcgccgggcg cttgggactg cagcgtggag aacggcggct gcgagcacgc gtgcaatgcg      720

atccctgggg ctccccgctg ccagtgccca gccggcgccg ccctgcaggc agacgggcgc      780

tcctgcaccg catccgcgac gcagtcctgc aacgacctct gcgagcactt ctgcgttccc      840

aaccccgacc agccgggctc ctactcgtgc atgtgcgaga ccggctaccg gctggcggcc      900

gaccaacacc ggtgcgagga cgtggatgac tgcatactgg agcccagtcc gtgtccgcag      960

cgctgtgtca acacacaggg tggcttcgag tgccactgct accctaacta cgacctggtg     1020

gacggcgagt gtgtggagcc cgtggacccg tgcttcagag ccaactgcga gtaccagtgc     1080

cagcccctga accaaactag ctacctctgc gtctgcgccg agggcttcgc gcccattccc     1140

cacgagccgc acaggtgcca gatgttttgc aaccagactg cctgtccagc cgactgcgac     1200

cccaacaccc aggctagctg tgagtgccct gaaggctaca tcctggacga cggtttcatc     1260

tgcacggaca tcgacgagtg cgaaaacggc ggcttctgct ccggggtgtg ccacaacctc     1320

cccggtacct tcgagtgcat ctgcgggccc gactcggccc ttgcccgcca cattggcacc     1380

gactgtgact ccggcaaggt ggacggtggc gacagcggct ctggcgagcc cccgcccagc     1440

ccgacgcccg gctccacctt gactcctccg gccgtggggc tcgtgcattc g              1491


<210>  4346
<211>  3456
<212>  DNA
<213>  Homo Sapiens

<400>  4346
aaccgcattc cagagtctgg cggagacaac agcgtgtttg acatctttga actcaccggg       60

gccgcccgca aggggtctgg gcgccgactg gtgaagggcc ccgacccttc cagcccagct      120

ttccgcatcg aggatgccaa cctgatcccc cctgtgcctg atgacaagtt ccaagacctg      180

gtggatgctg tgcgggcaga aaagggtttc ctccttctgg catccctgag gcagatgaag      240

aagacccggg gcacgctgct ggccctggag cggaaagacc actctggcca ggtcttcagc      300

gtggtgtcca atggcaaggc gggcaccctg gacctcagcc tgaccgtcca aggaaagcag      360

cacgtggtgt ctgtggaaga agctctcctg gcaaccggcc agtggaagag catcaccctg      420

tttgtgcagg aagacagggc ccagctgtac atcgactgtg aaaagatgga gaatgctgag      480

ttggacgtcc ccatccaaag cgtcttcacc agagacctgg ccagcatcgc cagactccgc      540

atcgcaaagg ggggcgtcaa tgacaatttc cagggggtgc tgcagaatgt gaggtttgtc      600

tttggaacca caccagaaga catcctcagg aacaaaggct gctccagctc taccagtgtc      660

ctcctcaccc ttgacaacaa cgtggtgaat ggttccagcc ctgccatccg cactaactac      720

attggccaca agacaaagga cttgcaagcc atctgcggca tctcctgtga tgagctgtcc      780

agcatggtcc tggaactcag gggcctgcgc accattgtga ccacgctgca ggacagcatc      840

cgcaaagtga ctgaagagaa caaagagttg gccaatgagc tgaggcggcc tcccctatgc      900

tatcacaacg gagttcagta cagaaataac gaggaatgga ctgttgatag ctgcactgag      960

tgtcactgtc agaactcagt taccatctgc aaaaaggtgt cctgccccat catgccctgc     1020

tccaatgcca cagttcctga tggagaatgc tgtcctcgct gttggcccag cgactctgcg     1080

gacgatggct ggtctccatg gtccgagtgg acctcctgtt ctacgagctg tggcaatgga     1140

attcagcagc gcggccgctc ctgcgatagc ctcaacaacc gatgtgaggg ctcctcggtc     1200

cagacacgga cctgccacat tcaggagtgt gacaagagat ttaaacagga tggtggctgg     1260

agccactggt ccccgtggtc atcttgttct gtgacatgtg gtgatggtgt gatcacaagg     1320

atccggctct gcaactctcc cagcccccag atgaacggga aaccctgtga aggcgaagcg     1380

cgggagacca aagcctgcaa gaaagacgcc tgccccatca atggaggctg gggtccttgg     1440

tcaccatggg acatctgttc tgtcacctgt ggaggagggg tacagaaacg tagtcgtctc     1500

tgcaacaacc ccacacccca gtttggaggc aaggactgcg ttggtgatgt aacagaaaac     1560

cagatctgca acaagcagga ctgtccaatt gatggatgcc tgtccaatcc ctgctttgcc     1620

ggcgtgaagt gtactagcta ccctgatggc agctggaaat gtggtgcttg tccccctggt     1680

tacagtggaa atggcatcca gtgcacagat gttgatgagt gcaaagaagt gcctgatgcc     1740

tgcttcaacc acaatggaga gcaccggtgt gagaacacgg accccggcta caactgcctg     1800

ccctgccccc cacgcttcac cggctcacag cccttcggcc agggtgtcga acatgccacg     1860

gccaacaaac aggtgtgcaa gccccgtaac ccctgcacgg atgggaccca cgactgcaac     1920

aagaacgcca agtgcaacta cctgggccac tatagcgacc ccatgtaccg ctgcgagtgc     1980

aagcctggct acgctggcaa tggcatcatc tgcggggagg acacagacct ggatggctgg     2040

cccaatgaga acctggtgtg cgtggccaat gcgacttacc actgcaaaaa ggataattgc     2100

cccaaccttc ccaactcagg gcaggaagac tatgacaagg atggaattgg tgatgcctgt     2160

gatgatgacg atgacaatga taaaattcca gatgacaggg acaactgtcc attccattac     2220

aacccagctc agtatgacta tgacagagat gatgtgggag accgctgtga caactgtccc     2280

tacaaccaca acccagatca ggcagacaca gacaacaatg gggaaggaga cgcctgtgct     2340

gcagacattg atggagacgg tatcctcaat gaacgggaca actgccagta cgtctacaat     2400

gtggaccaga gagacactga tatggatggg gttggagatc agtgtgacaa ttgccccttg     2460

gaacacaatc cggatcagct ggactctgac tcagaccgca ttggagatac ctgtgacaac     2520

aatcaggata ttgatgaaga tggccaccag aacaatctgg acaactgtcc ctatgtgccc     2580

aatgccaacc aggctgacca tgacaaagat ggcaagggag atgcctgtga ccacgatgat     2640

gacaacgatg gcattcctga tgacaaggac aactgcagac tcgtgcccaa tcccgaccag     2700

aaggactctg acggcgatgg tcgaggtgat gcctgcaaag atgattttga ccatgacagt     2760

gtgccagaca tcgatgacat ctgtcctgag aatgttgaca tcagtgagac cgatttccgc     2820

cgattccaga tgattcctct ggaccccaaa gggacatccc aaaatgaccc taactgggtt     2880

gtacgccatc agggtaaaga actcgtccag actgtcaact gtgatcctgg actcgctgta     2940

ggttatgatg agtttaatgc tgtggacttc agtggcacct tcttcatcaa caccgaaagg     3000

gacgatgact atgctggatt tgtctttggc taccagtcca gcagccgctt ttatgttgtg     3060

atgtggaagc aagtcaccca gtcctactgg gacaccaacc ccacgagggc tcagggatac     3120

tcgggccttt ctgtgaaagt tgtaaactcc accacagggc ctggcgagca cctgcggaac     3180

gccctgtggc acacaggaaa cacccctggc caggtgcgca ccctgtggca tgaccctcgt     3240

cacataggct ggaaagattt caccgcctac agatggcgtc tcagccacag gccaaagacg     3300

ggtttcatta gagtggtgat gtatgaaggg aagaaaatca tggctgactc aggacccatc     3360

tatgataaaa cctatgctgg tggtagacta gggttgtttg tcttctctca agaaatggtg     3420

ttcttctctg acctgaaata cgaatgtaga gatccc                               3456


<210>  4347
<211>  3462
<212>  DNA
<213>  Homo Sapiens

<400>  4347
ggtcaccagg acaaagacac gaccttcgac cttttcagta tcagcaacat caaccgcaag       60

accattggcg ccaagcagtt ccgcgggccc gaccccggcg tgccggctta ccgcttcgtg      120

cgctttgact acatcccacc ggtgaacgca gatgacctca gcaagatcac caagatcatg      180

cggcagaagg agggcttctt cctcacggcc cagctcaagc aggacggcaa gtccaggggc      240

acgctgttgg ctctggaggg ccccggtctc tcccagaggc agttcgagat cgtctccaac      300

ggccccgcgg acacgctgga tctcacctac tggattgacg gcacccggca tgtggtctcc      360

ctggaggacg tcggcctggc tgactcgcag tggaagaacg tcaccgtgca ggtggctggc      420

gagacctaca gcttgcacgt gggctgcgac ctcatagaca gcttcgctct ggacgagccc      480

ttctacgagc acctgcaggc ggaaaagagc cggatgtacg tggccaaagg ctctgccaga      540

gagagtcact tcaggggttt gcttcagaac gtccacctag tgtttgaaaa ctctgtggaa      600

gatattctaa gcaagaaggg ttgccagcaa ggccagggag ctgagatcaa cgccatcagt      660

gagaacacag agacgctgcg cctgggtccg catgtcacca ccgagtacgt gggccccagc      720

tcggagagga ggcccgaggt gtgcgaacgc tcgtgcgagg agctgggaaa catggtccag      780

gagctctcgg ggctccacgt cctcgtgaac cagctcagcg agaacctcaa gagagtgtcg      840

aatgataacc agtttctctg ggagctcatt ggtggccctc ctaagacaag gaacatgtca      900

gcttgctggc aggatggccg gttctttgcg gaaaatgaaa cgtgggtggt ggacagctgc      960

accacgtgta cctgcaagaa atttaaaacc atttgccacc aaatcacctg cccgcctgca     1020

acctgcgcca gtccatcctt tgtggaaggc gaatgctgcc cttcctgcct ccactcggtg     1080

gacggtgagg agggctggtc tccgtgggca gagtggaccc agtgctccgt gacgtgtggc     1140

tctgggaccc agcagagagg ccggtcctgt gacgtcacca gcaacacctg cttggggccc     1200

tccatccaga cacgggcttg cagtctgagc aagtgtgaca cccgcatccg gcaggacggc     1260

ggctggagcc actggtcacc ttggtcttca tgctctgtga cctgtggagt tggcaatatc     1320

acacgcatcc gtctctgcaa ctccccagtg ccccagatgg ggggcaagaa ttgcaaaggg     1380

agtggccggg agaccaaagc ctgccagggc gccccatgcc caatcgatgg ccgctggagc     1440

ccctggtccc cgtggtcggc ctgcactgtc acctgtgccg gtgggatccg ggagcgcacc     1500

cgggtctgca acagccctga gcctcagtac ggagggaagg cctgcgtggg ggatgtgcag     1560

gagcgtcaga tgtgcaacaa gaggagctgc cccgtggatg gctgtttatc caacccctgc     1620

ttcccgggag cccagtgcag cagcttcccc gatgggtcct ggtcatgcgg ctcctgccct     1680

gtgggcttct tgggcaatgg cacccactgt gaggacctgg acgagtgtgc cctggtcccc     1740

gacatctgct tctccaccag caaggtgcct cgctgtgtca acactcagcc tggcttccac     1800

tgcctgccct gcccgccccg atacagaggg aaccagcccg tcggggtcgg cctggaagca     1860

gccaagacgg aaaagcaagt gtgtgagccc gaaaacccat gcaaggacaa gacacacaac     1920

tgccacaagc acgcggagtg catctacctg ggccacttca gcgaccccat gtacaagtgc     1980

gagtgccaga caggctacgc gggcgacggg ctcatctgcg gggaggactc ggacctggac     2040

ggctggccca acctcaatct ggtctgcgcc accaacgcca cctaccactg catcaaggat     2100

aactgccccc atctgccaaa ttctgggcag gaagactttg acaaggacgg gattggcgat     2160

gcctgtgatg atgacgatga caatgacggt gtgaccgatg agaaggacaa ctgccagctc     2220

ctcttcaatc cccgccaggc tgactatgac aaggatgagg ttggggaccg ctgtgacaac     2280

tgcccttacg tgcacaaccc tgcccagatc gacacagaca acaatggaga gggtgacgcc     2340

tgctccgtgg acattgatgg ggacgatgtc ttcaatgaac gagacaattg tccctacgtc     2400

tacaacactg accagaggga cacggatggt gacggtgtgg gggatcactg tgacaactgc     2460

cccctggtgc acaaccctga ccagaccgac gtggacaatg accttgttgg ggaccagtgt     2520

gacaacaacg aggacataga tgacgacggc caccagaaca accaggacaa ctgcccctac     2580

atctccaacg ccaaccaggc tgaccatgac agagacggcc agggcgacgc ctgtgaccct     2640

gatgatgaca acgatggcgt ccccgatgac agggacaact gccggcttgt gttcaaccca     2700

gaccaggagg acttggacgg tgatggacgg ggtgatattt gtaaagatga ttttgacaat     2760

gacaacatcc cagatattga tgatgtgtgt cctgaaaaca atgccatcag tgagacagac     2820

ttcaggaact tccagatggt ccccttggat cccaaaggga ccacccaaat tgatcccaac     2880

tgggtcattc gccatcaagg caaggagctg gttcagacag ccaactcgga ccccggcatc     2940

gctgtaggtt ttgacgagtt tgggtctgtg gacttcagtg gcacattcta cgtaaacact     3000

gaccgggacg acgactatgc cggcttcgtc tttggttacc agtcaagcag ccgcttctat     3060

gtggtgatgt ggaagcaggt gacgcagacc tactgggagg accagcccac gcgggcctat     3120

ggctactccg gcgtgtccct caaggtggtg aactccacca cggggacggg cgagcacctg     3180

aggaacgcgc tgtggcacac ggggaacacg ccggggcagg tgcgaacctt atggcacgac     3240

cccaggaaca ttggctggaa ggactacacg gcctataggt ggcacctgac tcacaggccc     3300

aagactggct acatcagagt cttagtgcat gaaggaaaac aggtcatggc agactcagga     3360

cctatctatg accaaaccta cgctggcggg cggctgggtc tatttgtctt ctctcaagaa     3420

atggtctatt tctcagacct caagtacgaa tgcagagata tt                        3462


<210>  4348
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  4348
actgacacag acatcgatgg ctacccagac caagcactgc cctgcatgga caacaacaaa       60

cactgcaaac aggacaactg ccttttgaca cccaactctg ggcaggaaga tgctgataat      120

gatggtgtgg gggaccagtg tgatgatgat gctgatgggg atgggatcaa gaatgttgag      180

gacaactgcc ggctgttccc caacaaagac cagcagaact cagatacaga ttcatttggt      240

gatgcctgtg acaattgccc caacgttccc aacaatgacc agaaggacac agatggcaat      300

ggggaaggag atgcctgtga caacgacgtg gatggggatg gcatccccaa tggattggac      360

aattgcccta aagtccccaa cccactacag acagacaggg atgaggacgg ggtgggagat      420

gcttgcgaca gctgccctga aatgagcaat cctacccaga cagatgcaga cagcgacctg      480

gtgggggatg tctgtgatac taatgaagac agcgatgggg atgggcatca ggacaccaag      540

gacaactgcc cacagctgcc aaatagctcc cagctggact ctgataacga tggacttgga      600

gatgagtgtg atggggatga tgacaatgat ggcatcccag attatgtgcc tcctggtccc      660

gataactgcc gcctggtacc caatcccaat cagaaggact cagatggcaa tggcgttggt      720

gatgtgtgtg aggatgactt tgacaatgat gctgtggtcg accccctgga tgtgtgtcct      780

gaaagtgcag aggtaacgct tacggatttt cgggcctatc agaccgtcgt cctggatcct      840

gagggtgatg ctcagattga cccaaactgg gttgtgctca accagggcat ggaaatcgtt      900

cagaccatga acagtgaccc tggcttggca gttggataca cggccttcaa tggtgtggac      960

tttgaaggca ccttccatgt gaacacagtg actgatgatg actacgcagg ctttctcttc     1020

agttatcaag acagtggccg cttctacgta gtcatgtgga agcagaccga gcagacctac     1080

tggcaggcta cacccttccg ggcggttgcc cagcccgggc tgcagctcaa ggcagtgaca     1140

tcagtgtctg gcccaggtga gcacctccga aatgccctgt ggcatactgg ccacacccct     1200

gatcaggtac gactgctgtg gacagaccca cgaaatgtgg gctggcggga caagacctcc     1260

tatcgctggc agcttctgca ccggcctcaa gttggctaca ttcgggtgaa gctctatgag     1320

ggaccccagc ttgtggcgga ttctggggtg atcattgaca catccatgcg aggggggcgt     1380

cttggtgtat tctgcttctc ccaagaaaac ataatttggt ccaatctcca gtatcgatgc     1440

aatgacacag tgcctgagga ctttgagcca ttccggaggc agctgctcca gggaagggtg     1500


<210>  4349
<211>  2805
<212>  DNA
<213>  Homo Sapiens

<400>  4349
accccccagg tctttgacct tctcccatct tccagtcaga ggctaaaccc aggcgctctg       60

ctgccagtcc tgacagaccc cgccctgaat gatctctatg tgatttccac cttcaagctg      120

cagactaaaa gttcagccac catcttcggt ctttactctt caactgacaa cagtaaatat      180

tttgaattta ctgtgatggg acgcttaaac aaagccatcc tccgttacct gaagaacgat      240

gggaaggtgc atttggtggt tttcaacaac ctgcagctgg cagacggaag gcggcacagg      300

atcctcctga ggctgagcaa tttgcagcga ggggccggct ccctagagct ctacctggac      360

tgcatccagg tggattccgt tcacaatctc cccagggcct ttgctggccc ctcccagaaa      420

cctgagacca ttgaattgag gactttccag aggaagccac aggacttctt ggaagagctg      480

aagctggtgg tgagaggctc actgttccag gtggccagcc tgcaagactg cttcctgcag      540

cagagtgagc cactggctgc cacaggcaca ggggacttta accggcagtt cttgggtcaa      600

atgacacaat taaaccaact cctgggagag gtgaaggacc ttctgagaca gcaggttaag      660

gaaacatcat ttttgcgaaa caccatagct gaatgccagg cttgcggtcc tctcaagttt      720

cagtctccga ccccaagcac ggtggtgccc ccggctcccc ctgcaccgcc aacacgccca      780

cctcgtcggt gtgactccaa cccatgtttc cgaggtgtcc aatgtaccga cagtagagat      840

ggcttccagt gtgggccctg ccccgagggc tacacaggaa acgggatcac ctgtattgat      900

gttgatgagt gcaaatacca tccctgctac ccgggcgtgc actgcataaa tttgtctcct      960

ggcttcagat gtgacgcctg cccagtgggc ttcacagggc ccatggtgca gggtgttggg     1020

atcagttttg ccaagtcaaa caagcaggtc tgcactgaca ttgatgagtg tcgaaatgga     1080

gcgtgcgttc ccaactcgat ctgcgttaat actttgggat cttaccgctg tgggccttgt     1140

aagccggggt atactggtga tcagataagg ggatgcaaag cggaaagaaa ctgcagaaac     1200

ccagagctga acccttgcag tgtgaatgcc cagtgcattg aagagaggca gggggatgtg     1260

acatgtgtgt gtggagtcgg ttgggctgga gatggctata tctgtggaaa ggatgtggac     1320

atcgacagtt accccgacga agaactgcca tgctctgcca ggaactgtaa aaaggacaac     1380

tgcaaatatg tgccaaattc tggccaagaa gatgcagaca gagatggcat tggcgacgct     1440

tgtgacgagg atgctgacgg agatgggatc ctgaatgagc aggataactg tgtcctgatt     1500

cataatgtgg accaaaggaa cagcgataaa gatatctttg gggatgcctg tgataactgc     1560

ctgagtgtct taaataacga ccagaaagac accgatgggg atggaagagg agatgcctgt     1620

gatgatgaca tggatggaga tggaataaaa aacattctgg acaactgccc aaaatttccc     1680

aatcgtgacc aacgggacaa ggatggtgat ggtgtggggg atgcctgtga cagttgtcct     1740

gatgtcagca accctaacca gtctgatgtg gataatgatc tggttgggga ctcctgtgac     1800

accaatcagg acagtgatgg agatgggcac caggacagca cagacaactg ccccaccgtc     1860

attaacagtg cccagctgga caccgataag gatggaattg gtgacgagtg tgatgatgat     1920

gatgacaatg atggtatccc agacctggtg ccccctggac cagacaactg ccggctggtc     1980

cccaacccag cccaggagga tagcaacagc gacggagtgg gagacatctg tgagtctgac     2040

tttgaccagg accaggtcat cgatcggatc gacgtctgcc cagagaacgc agaggtcacc     2100

ctgaccgact tcagggctta ccagaccgtg gtcctggatc ctgaagggga tgcccagatc     2160

gatcccaact gggtggtcct gaaccagggc atggagattg tacagaccat gaacagtgat     2220

cctggcctgg cagtggggta cacagctttt aatggagttg acttcgaagg gaccttccat     2280

gtgaataccc agacagatga tgactatgca ggctttatct ttggctacca agatagctcc     2340

agcttctacg tggtcatgtg gaagcagacg gagcagacat attggcaagc caccccattc     2400

cgagcagttg cagaacctgg cattcagctc aaggctgtga agtctaagac aggtccaggg     2460

gagcatctcc ggaactccct gtggcacacg ggggacacca gtgaccaggt caggctgctg     2520

tggaaggact ccaggaatgt gggctggaag gacaaggtgt cctaccgctg gttcctacag     2580

cacaggcccc aggtgggcta catcagggta cgattttatg aaggctctga gttggtggct     2640

gactctggcg tcaccataga caccacaatg cgtggaggcc gacttggcgt tttctgcttc     2700

tctcaagaaa acatcatctg gtccaacctc aagtatcgct gcaatgacac catccctgag     2760

gacttccaag agtttcaaac ccagaatttc gaccgcttcg ataat                     2805


<210>  4350
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  4350
cagaaggtga ccagcctaac ggcctgccta gtggaccaga gccttcgtct ggactgccgc       60

catgagaata ccagcagttc acccatccag tacgagttca gcctgacccg tgagacaaag      120

aagcacgtgc tctttggcac tgtgggggtg cctgagcaca cataccgctc ccgaaccaac      180

ttcaccagca aatacaacat gaaggtcctc tacttatccg ccttcactag caaggacgag      240

ggcacctaca cgtgtgcact ccaccactct ggccattccc cacccatctc ctcccagaac      300

gtcacagtgc tcagagacaa actggtcaag tgt                                   333


<210>  4351
<211>  2214
<212>  DNA
<213>  Homo Sapiens

<400>  4351
gcggtggacc tgacgctgct ggccaacctg cggctcacgg acccccagcg cttcttcctg       60

acttgcgtgt ctggggaggc cggggcgggg aggggctcgg acgcctgggg cccgcccctg      120

ctgctggaga aggacgaccg tatcgtgcgc accccgcccg ggccacccct gcgcctggcg      180

cgcaacggtt cgcaccaggt cacgcttcgc ggcttctcca agccctcgga cctcgtgggc      240

gtcttctcct gcgtgggcgg tgctggggcg cggcgcacgc gcgtcatcta cgtgcacaac      300

agccctggag cccacctgct tccagacaag gtcacacaca ctgtgaacaa aggtgacacc      360

gctgtacttt ctgcacgtgt gcacaaggag aagcagacag acgtgatctg gaagagcaac      420

ggatcctact tctacaccct ggactggcat gaagcccagg atgggcggtt cctgctgcag      480

ctcccaaatg tgcagccacc atcgagcggc atctacagtg ccacttacct ggaagccagc      540

cccctgggca gcgccttctt tcggctcatc gtgcggggtt gtggggctgg gcgctggggg      600

ccaggctgta ccaaggagtg cccaggttgc ctacatggag gtgtctgcca cgaccatgac      660

ggcgaatgtg tatgcccccc tggcttcact ggcacccgct gtgaacaggc ctgcagagag      720

ggccgttttg ggcagagctg ccaggagcag tgcccaggca tatcaggctg ccggggcctc      780

accttctgcc tcccagaccc ctatggctgc tcttgtggat ctggctggag aggaagccag      840

tgccaagaag cttgtgcccc tggtcatttt ggggctgatt gccgactcca gtgccagtgt      900

cagaatggtg gcacttgtga ccggttcagt ggttgtgtct gcccctctgg gtggcatgga      960

gtgcactgtg agaagtcaga ccggatcccc cagatcctca acatggcctc agaactggag     1020

ttcaacttag agacgatgcc ccggatcaac tgtgcagctg cagggaaccc cttccccgtg     1080

cggggcagca tagagctacg caagccagac ggcactgtgc tcctgtccac caaggccatt     1140

gtggagccag agaagaccac agctgagttc gaggtgcccc gcttggttct tgcggacagt     1200

gggttctggg agtgccgtgt gtccacatct ggcggccaag acagccggcg cttcaaggtc     1260

aatgtgaaag tgccccccgt gcccctggct gcacctcggc tcctgaccaa gcagagccgc     1320

cagcttgtgg tctccccgct ggtctcgttc tctggggatg gacccatctc cactgtccgc     1380

ctgcactacc ggccccagga cagtaccatg gactggtcga ccattgtggt ggaccccagt     1440

gagaacgtga cgttaatgaa cctgaggcca aagacaggat acagtgttcg tgtgcagctg     1500

agccggccag gggaaggagg agagggggcc tgggggcctc ccaccctcat gaccacagac     1560

tgtcctgagc ctttgttgca gccgtggttg gagggctggc atgtggaagg cactgaccgg     1620

ctgcgagtga gctggtcctt gcccttggtg cccgggccac tggtgggcga cggtttcctg     1680

ctgcgcctgt gggacgggac acgggggcag gagcggcggg agaacgtctc atccccccag     1740

gcccgcactg ccctcctgac gggactcacg cctggcaccc actaccagct ggatgtgcag     1800

ctctaccact gcaccctcct gggcccggcc tcgccccctg cacacgtgct tctgcccccc     1860

agtgggcctc cagccccccg acacctccac gcccaggccc tctcagactc cgagatccag     1920

ctgacatgga agcacccgga ggctctgcct gggccaatat ccaagtacgt tgtggaggtg     1980

caggtggctg ggggtgcagg agacccactg tggatagacg tggacaggcc tgaggagaca     2040

agcaccatca tccgtggcct caacgccagc acgcgctacc tcttccgcat gcgggccagc     2100

attcaggggc tcggggactg gagcaacaca gtagaagagt ccaccctggg caacgggctg     2160

caggctgagg gcccagtcca agagagccgg gcagctgaag agggcctgga tcag           2214


<210>  4352
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  4352
atgatgacag gcacaataga aacaacgggg aacatttctg cagagaaagg tggctctatc       60

atcttacaat gtcacctctc ctccaccacg gcacaagtga cccaggtcaa ctgggagcag      120

caggaccagc ttctggccat ttgtaatgct gacttggggt ggcacatctc cccatccttc      180

aaggatcgag tggccccagg tcccggcctg ggcctcaccc tccagtcgct gaccgtgaac      240

gatacagggg agtacttctg catctatcac acctaccctg atgggacgta cactgggaga      300

atcttcctgg aggtcctaga aagctcagtg gctgagcacg gtgccaggtt ccagattcca      360


<210>  4353
<211>  870
<212>  DNA
<213>  Homo Sapiens

<400>  4353
gagactgttg tgacggaggt tttgggtcac cgggtgactt tgccctgtct gtactcatcc       60

tggtctcaca acagcaacag catgtgctgg gggaaagacc agtgccccta ctccggttgc      120

aaggaggcgc tcatccgcac tgatggaatg agggtgacct caagaaagtc agcaaaatat      180

agacttcagg ggactatccc gagaggtgat gtctccttga ccatcttaaa ccccagtgaa      240

agtgacagcg gtgtgtactg ctgccgcata gaagtgcctg gctggttcaa cgatgtaaag      300

ataaacgtgc gcctgaatct acagagagcc tcaacaacca cgcacagaac agcaaccacc      360

accacacgca gaacaacaac aacaagcccc accaccaccc gacaaatgac aacaacccca      420

gctgcacttc caacaacagt cgtgaccaca cccgatctca caaccggaac accactccag      480

atgacaacca ttgccgtctt cacaacagca aacacgtgcc tttcactaac cccaagcacc      540

cttccggagg aagccacagg tcttctgact cccgagcctt ctaaggaagg gcccatcctc      600

actgcagaat cagaaactgt cctccccagt gattcctgga gtagtgctga gtctacttct      660

gctgacactg tcctgctgac atccaaagag tccaaagttt gggatctccc atcaacatcc      720

cacgtgtcaa tgtggaaaac gagtgattct gtgtcttctc ctcagcctgg agcatctgat      780

acagcagttc ctgagcagaa caaaacaaca aaaacaggac agatggatgg aatacccatg      840

tcaatgaaga atgaaatgcc catctcccaa                                       870


<210>  4354
<211>  2598
<212>  DNA
<213>  Homo Sapiens

<400>  4354
gccgctacat caagaacgga aagaatatgg cctggaggcg ttattcctta tgttatagga       60

ggaaacttca ctggcagcca gagagccatg ttcaagcagg ccatgaggca ctgggaaaag      120

cacacatgtg tgactttcat agaaagaagt gatgaagaga gttacattgt attcacctat      180

aggccttgtg gatgctgctc ctatgtaggt cggcgaggaa atggacctca ggcaatctct      240

atcggcaaga actgtgataa atttgggatt gttgttcatg aattgggtca tgtgataggc      300

ttttggcatg aacacacaag accagatcga gataaccacg taactatcat aagagaaaac      360

atccagccag gtcaagagta caattttctg aagatggagc ctggagaagt aaactcactt      420

ggagaaagat atgatttcga cagtatcatg cactatgcca ggaacacctt ctcaaggggg      480

atgtttctgg ataccattct cccctcccgt gatgataatg gcatacgtcc tgcaattggt      540

cagcgaaccc gtctaagcaa aggagatatc gcacaggcaa gaaagctgta tagatgtcca      600

gcatgtggag aaactctaca agaatccaat ggcaaccttt cctctccagg atttcccaat      660

ggctaccctt cttacacaca ctgcatctgg agagtttctg tgaccccagg ggagaagatt      720

gttttaaatt ttacaacgat ggatctatac aagagtagtt tgtgctggta tgactatatt      780

gaagtaagag acgggtactg gagaaaatca cctctccttg gtagattctg tggggacaaa      840

ttgcctgaag ttcttacttc tacagacagc agaatgtgga ttgagtttcg tagcagcagt      900

aattgggtag gaaaaggctt tgcagctgtc tatgaagcga tctgtggagg tgagatacgt      960

aaaaatgaag gacagattca gtctcccaat tatcctgatg actatcgccc gatgaaagaa     1020

tgtgtgtgga aaataacagt gtctgagagc taccacgtcg ggctgacctt tcagtccttt     1080

gagattgaaa gacatgacaa ttgtgcttat gactacctgg aagttagaga tggaaccagt     1140

gaaaatagcc ctttgatagg gcgtttctgt ggttatgaca aacctgaaga cataagatct     1200

acctccaata ctttgtggat gaagtttgtt tctgacggaa ctgtgaacaa agcagggttt     1260

gctgctaact tttttaaaga ggaagatgag tgtgccaaac ctgaccgtgg aggctgtgag     1320

cagcgatgtc tgaacactct gggcagttac cagtgtgcct gtgagcctgg ctatgagctg     1380

ggcccagaca gaaggagctg tgaagctgct tgtggtggac ttcttaccaa acttaacggc     1440

accataacca cccctggctg gcccaaggag taccctccta ataagaactg tgtgtggcaa     1500

gtggttgcac caacccagta cagaatttct gtgaagtttg agttttttga attggaaggc     1560

aatgaagttt gcaaatatga ttatgtggag atctggagtg gtctttcctc tgagtctaaa     1620

ctgcatggca aattctgtgg cgctgaagtg cctgaagtga tcacatccca gttcaacaat     1680

atgagaattg aattcaaatc tgacaatact gtatccaaga agggcttcaa agcacatttt     1740

ttctcagaca aagatgaatg ctctaaggat aatggtggat gtcagcacga atgtgtcaac     1800

acgatgggga gctacatgtg tcaatgccgt aatggatttg tgctacatga caataaacat     1860

gattgcaagg aagctgagtg tgaacagaag atccacagtc caagtggcct catcaccagt     1920

cccaactggc cagacaagta cccaagcagg aaagaatgca cttgggaaat cagcgccact     1980

cctggccacc gaatcaaatt agcctttagt gaatttgaga ttgagcagca tcaagaatgt     2040

gcttatgacc acttagaagt atttgatgga gaaacagaaa agtcaccgat tcttggacga     2100

ctatgtggca acaagatacc agatcccctt gtggctactg gaaataaaat gtttgttcgg     2160

tttgtttctg atgcatctgt tcaaagaaaa ggctttcaag ccacacattc tacagagtgt     2220

ggcggacgat tgaaagcaga atcaaaacca agagatctgt actcacatgc tcagtttggt     2280

gataacaact acccaggaca ggttgactgt gaatggctat tagtatcaga acggggctct     2340

cgacttgaat tatccttcca gacatttgaa gtggaggaag aagcagactg tggctatgac     2400

tatgtggagc tctttgatgg tcttgattca acagctgtgg ggcttggtcg attctgtgga     2460

tccgggccac cagaagagat ttattcaatt ggagattcag ttttaattca tttccacact     2520

gatgacacaa tcaacaagaa gggatttcat ataagataca aaagcataag atatccagat     2580

accacacata ccaaaaaa                                                   2598


<210>  4355
<211>  2598
<212>  DNA
<213>  Homo Sapiens

<400>  4355
gccacaacct caaggacaga gaggatatgg cctggaggag tcatccccta cgtcattgga       60

gggaacttca ctgggagcca gagggccatt tttaagcagg ccatgagaca ctgggagaag      120

cacacctgtg tgaccttcat agaaaggacg gatgaggaaa gctttattgt attcagttac      180

agaacctgtg gctgttgctc ctatgttggg cgccgaggag gaggcccaca ggccatatcc      240

attgggaaga actgtgacaa gtttggcatt gtggctcacg agctgggcca tgtggttggg      300

ttttggcatg aacacacccg gccagacaga gaccaacatg tcaccatcat cagggaaaac      360

atccagccag gtcaggagta taatttctta aaaatggaag ctggggaagt gagctctctg      420

ggagagacat acgactttga cagcatcatg cactacgccc ggaacacctt ctcaagagga      480

gttttcttag acaccatcct tccccgtcaa gatgacaatg gcgtcaggcc aaccattggc      540

cagcgcgtgc ggctcagtca gggagacata gctcaagccc ggaagctgta caaatgccca      600

gcgtgtgggg agaccctgca ggacacaacg ggaaactttt ctgcacctgg tttcccaaat      660

gggtacccat cttactccca ctgcgtctgg aggatctcgg tcaccccagg ggaaaagatc      720

gtattaaact tcacatccat ggatttgttt aaaagccgac tgtgctggta tgattacgtg      780

gaggtccggg atggttactg gagaaaagcc ccccttttgg gcaggttttg tggcgataag      840

atcccggagc ccctcgtctc cacggacagc cggctctggg tggagttccg cagcagcagc      900

aacatcttgg gcaagggctt ctttgcagcg tacgaagcta cctgcggggg agacatgaac      960

aaagatgccg gtcagattca atctcccaac tatccggatg actacagacc ttccaaggaa     1020

tgtgtctgga ggattacggt ttcagagggg tttcacgtgg gacttacctt ccaagctttt     1080

gagattgaaa ggcacgacag ctgtgcatat gactacctgg aagtccggga tggccccacg     1140

gaagagagtg ccctgatcgg ccacttttgt ggctatgaga agccggagga tgtgaaatcg     1200

agctccaaca gactgtggat gaagtttgtg tccgatggct ctatcaataa agcgggcttt     1260

gcagccaatt ttttcaagga ggtggatgag tgttcctggc cagatcacgg cgggtgcgag     1320

catcgctgtg tgaacacgct gggcagctac aagtgtgcct gtgaccctgg ctacgagctg     1380

gccgccgata agaagatgtg tgaagtggcc tgtggcggtt tcattaccaa gctgaatgga     1440

accatcacca gccctgggtg gccgaaggag tatcccacaa acaaaaactg tgtctggcag     1500

gtggtggccc ccgctcagta ccggatctcc cttcagtttg aagtgtttga actggaaggc     1560

aatgacgtct gtaagtacga ctttgtagag gtgcgcagcg gcctgtcccc cgacgccaag     1620

ctgcacggca ggttctgcgg ctctgagacg ccggaggtca tcacctcgca gagcaacaac     1680

atgcgcgtgg agttcaagtc cgacaacacc gtctccaagc gcggcttcag ggcccacttc     1740

ttctcagata aggacgagtg tgccaaggac aacggcgggt gtcagcatga gtgcgtcaac     1800

accttcggga gctacctgtg caggtgcaga aacggctact ggctccacga gaatgggcat     1860

gactgcaaag aggctggctg tgcacacaag atcagcagtg tggaggggac cctggcgagc     1920

cccaactggc ctgacaaata ccccagccgg agggagtgta cctggaacat ctcttcgact     1980

gcaggccaca gagtgaaact cacctttaat gagtttgaga tcgagcagca ccaggaatgt     2040

gcctatgacc acctggaaat gtatgacggg ccggacagcc tggcccccat tctgggccgt     2100

ttctgcggca gcaagaaacc agaccccacg gtggcttccg gcagcagtat gtttctcagg     2160

ttttattcgg atgcctcagt gcagaggaaa ggcttccagg cagtgcacag cacagagtgc     2220

gggggcaggc tgaaggctga agtgcagacc aaagagctct attcccacgc ccagtttggg     2280

gacaacaact acccgagcga ggcccgctgt gactgggtga tcgtggcaga ggacggctac     2340

ggcgtggagc tgacattccg gacctttgag gttgaggagg aggccgactg cggctacgac     2400

tacatggaag cctacgacgg ctacgacagc tcagcgccca ggctcggccg cttctgtggc     2460

tctgggccat tagaagaaat ctactctgca ggtgattccc tgatgattcg attccgcaca     2520

gatgacacca tcaacaagaa aggctttcat gcccgataca ccagcaccaa gttccaggat     2580

gccctgcaca tgaagaaa                                                   2598


<210>  4356
<211>  1668
<212>  DNA
<213>  Homo Sapiens

<400>  4356
agtgaatttt tagttgatag gtcaaaaaac ggtctcatcc acgttcctaa agacctatcc       60

cagaaaacaa caatcttaaa tatatcgcaa aattatatat ctgagctttg gacttctgac      120

atcttatcac tgtcaaaact gaggattttg ataatttctc ataatagaat ccagtatctt      180

gatatcagtg ttttcaaatt caaccaggaa ttggaatact tggatttgtc ccacaacaag      240

ttggtgaaga tttcttgcca ccctactgtg aacctcaagc acttggacct gtcatttaat      300

gcatttgatg ccctgcctat atgcaaagag tttggcaata tgtctcaact aaaatttctg      360

gggttgagca ccacacactt agaaaaatct agtgtgctgc caattgctca tttgaatatc      420

agcaaggtct tgctggtctt aggagagact tatggggaaa aagaagaccc tgagggcctt      480

caagacttta acactgagag tctgcacatt gtgttcccca caaacaaaga attccatttt      540

attttggatg tgtcagtcaa gactgtagca aatctggaac tatctaatat caaatgtgtg      600

ctagaagata acaaatgttc ttacttccta agtattctgg cgaaacttca aacaaatcca      660

aagttatcaa atcttacctt aaacaacatt gaaacaactt ggaattcttt cattaggatc      720

ctccagctgg tttggcatac aactgtatgg tatttctcaa tttcaaacgt gaagctacag      780

ggtcagctgg acttcagaga ttttgattat tctggcactt ccttgaaggc cttgtctata      840

caccaagttg tcagcgatgt gttcggtttt ccgcaaagtt atatctatga aatcttttcg      900

aatatgaaca tcaaaaattt cacagtgtct ggtacacgca tggtccacat gctttgccca      960

tccaaaatta gcccgttcct gcatttggat ttttccaata atctcttaac agacacggtt     1020

tttgaaaatt gtgggcacct tactgagttg gagacactta ttttacaaat gaatcaatta     1080

aaagaacttt caaaaatagc tgaaatgact acacagatga agtctctgca acaattggat     1140

attagccaga attctgtaag ctatgatgaa aagaaaggag actgttcttg gactaaaagt     1200

ttattaagtt taaatatgtc ttcaaatata cttactgaca ctattttcag atgtttacct     1260

cccaggatca aggtacttga tcttcacagc aataaaataa agagcattcc taaacaagtc     1320

gtaaaactgg aagctttgca agaactcaat gttgctttca attctttaac tgaccttcct     1380

ggatgtggca gctttagcag cctttctgta ttgatcattg atcacaattc agtttcccac     1440

ccatcggctg atttcttcca gagctgccag aagatgaggt caataaaagc aggggacaat     1500

ccattccaat gtacctgtga gctaggagaa tttgtcaaaa atatagacca agtatcaagt     1560

gaagtgttag agggctggcc tgattcttat aagtgtgact acccggaaag ttatagagga     1620

accctactaa aggactttca catgtctgaa ttatcctgca acataact                  1668


<210>  4357
<211>  1671
<212>  DNA
<213>  Homo Sapiens

<400>  4357
gatgctccag agctgccaga agaaagggaa ctgatgacca actgctccaa catgtctcta       60

agaaaggttc ccgcagactt gaccccagcc acaacgacac tggatttatc ctataacctc      120

ctttttcaac tccagagttc agattttcat tctgtctcca aactgagagt tttgattcta      180

tgccataaca gaattcaaca gctggatctc aaaacctttg aattcaacaa ggagttaaga      240

tatttagatt tgtctaataa cagactgaag agtgtaactt ggtatttact ggcaggtctc      300

aggtatttag atctttcttt taatgacttt gacaccatgc ctatctgtga ggaagctggc      360

aacatgtcac acctggaaat cctaggtttg agtggggcaa aaatacaaaa atcagatttc      420

cagaaaattg ctcatctgca tctaaatact gtcttcttag gattcagaac tcttcctcat      480

tatgaagaag gtagcctgcc catcttaaac acaacaaaac tgcacattgt tttaccaatg      540

gacacaaatt tctgggttct tttgcgtgat ggaatcaaga cttcaaaaat attagaaatg      600

acaaatatag atggcaaaag ccaatttgta agttatgaaa tgcaacgaaa tcttagttta      660

gaaaatgcta agacatcggt tctattgctt aataaagttg atttactctg ggacgacctt      720

ttccttatct tacaatttgt ttggcataca tcagtggaac actttcagat ccgaaatgtg      780

acttttggtg gtaaggctta tcttgaccac aattcatttg actactcaaa tactgtaatg      840

agaactataa aattggagca tgtacatttc agagtgtttt acattcaaca ggataaaatc      900

tatttgcttt tgaccaaaat ggacatagaa aacctgacaa tatcaaatgc acaaatgcca      960

cacatgcttt tcccgaatta tcctacgaaa ttccaatatt taaattttgc caataatatc     1020

ttaacagacg agttgtttaa aagaactatc caactgcctc acttgaaaac tctcattttg     1080

aatggcaata aactggagac actttcttta gtaagttgct ttgctaacaa cacacccttg     1140

gaacacttgg atctgagtca aaatctatta caacataaaa atgatgaaaa ttgctcatgg     1200

ccagaaactg tggtcaatat gaatctgtca tacaataaat tgtctgattc tgtcttcagg     1260

tgcttgccca aaagtattca aatacttgac ctaaataata accaaatcca aactgtacct     1320

aaagagacta ttcatctgat ggccttacga gaactaaata ttgcatttaa ttttctaact     1380

gatctccctg gatgcagtca tttcagtaga ctttcagttc tgaacattga aatgaacttc     1440

attctcagcc catctctgga ttttgttcag agctgccagg aagttaaaac tctaaatgcg     1500

ggaagaaatc cattccggtg tacctgtgaa ttaaaaaatt tcattcagct tgaaacatat     1560

tcagaggtca tgatggttgg atggtcagat tcatacacct gtgaataccc tttaaaccta     1620

aggggaacta ggttaaaaga cgttcatctc cacgaattat cttgcaacac a              1671


<210>  4358
<211>  1704
<212>  DNA
<213>  Homo Sapiens

<400>  4358
gaatcctcca atcaggcttc tctgtcttgt gaccgcaatg gtatctgcaa gggcagctca       60

ggatctttaa actccattcc ctcagggctc acagaagctg taaaaagcct tgacctgtcc      120

aacaacagga tcacctacat tagcaacagt gacctacaga ggtgtgtgaa cctccaggct      180

ctggtgctga catccaatgg aattaacaca atagaggaag attctttttc ttccctgggc      240

agtcttgaac atttagactt atcctataat tacttatcta atttatcgtc ttcctggttc      300

aagccccttt cttctttaac attcttaaac ttactgggaa atccttacaa aaccctaggg      360

gaaacatctc ttttttctca tctcacaaaa ttgcaaatcc tgagagtggg aaatatggac      420

accttcacta agattcaaag aaaagatttt gctggactta ccttccttga ggaacttgag      480

attgatgctt cagatctaca gagctatgag ccaaaaagtt tgaagtcaat tcagaacgta      540

agtcatctga tccttcatat gaagcagcat attttactgc tggagatttt tgtagatgtt      600

acaagttccg tggaatgttt ggaactgcga gatactgatt tggacacttt ccatttttca      660

gaactatcca ctggtgaaac aaattcattg attaaaaagt ttacatttag aaatgtgaaa      720

atcaccgatg aaagtttgtt tcaggttatg aaacttttga atcagatttc tggattgtta      780

gaattagagt ttgatgactg tacccttaat ggagttggta attttagagc atctgataat      840

gacagagtta tagatccagg taaagtggaa acgttaacaa tccggaggct gcatattcca      900

aggttttact tattttatga tctgagcact ttatattcac ttacagaaag agttaaaaga      960

atcacagtag aaaacagtaa agtttttctg gttccttgtt tactttcaca acatttaaaa     1020

tcattagaat acttggatct cagtgaaaat ttgatggttg aagaatactt gaaaaattca     1080

gcctgtgagg atgcctggcc ctctctacaa actttaattt taaggcaaaa tcatttggca     1140

tcattggaaa aaaccggaga gactttgctc actctgaaaa acttgactaa cattgatatc     1200

agtaagaata gttttcattc tatgcctgaa acttgtcagt ggccagaaaa gatgaaatat     1260

ttgaacttat ccagcacacg aatacacagt gtaacaggct gcattcccaa gacactggaa     1320

attttagatg ttagcaacaa caatctcaat ttattttctt tgaatttgcc gcaactcaaa     1380

gaactttata tttccagaaa taagttgatg actctaccag atgcctccct cttacccatg     1440

ttactagtat tgaaaatcag taggaatgca ataactacgt tttctaagga gcaacttgac     1500

tcatttcaca cactgaagac tttggaagct ggtggcaata acttcatttg ctcctgtgaa     1560

ttcctctcct tcactcagga gcagcaagca ctggccaaag tcttgattga ttggccagca     1620

aattacctgt gtgactctcc atcccatgtg cgtggccagc aggttcagga tgtccgcctc     1680

tcggtgtcgg aatgtcacag gaca                                            1704


<210>  4359
<211>  2043
<212>  DNA
<213>  Homo Sapiens

<400>  4359
tccaccacca agtgcactgt tagccatgaa gttgctgact gcagccacct gaagttgact       60

caggtacccg atgatctacc cacaaacata acagtgttga accttaccca taatcaactc      120

agaagattac cagccgccaa cttcacaagg tatagccagc taactagctt ggatgtagga      180

tttaacacca tctcaaaact ggagccagaa ttgtgccaga aacttcccat gttaaaagtt      240

ttgaacctcc agcacaatga gctatctcaa ctttctgata aaacctttgc cttctgcacg      300

aatttgactg aactccatct catgtccaac tcaatccaga aaattaaaaa taatcccttt      360

gtcaagcaga agaatttaat cacattagat ctgtctcata atggcttgtc atctacaaaa      420

ttaggaactc aggttcagct ggaaaatctc caagagcttc tattatcaaa caataaaatt      480

caagcgctaa aaagtgaaga actggatatc tttgccaatt catctttaaa aaaattagag      540

ttgtcatcga atcaaattaa agagttttct ccagggtgtt ttcacgcaat tggaagatta      600

tttggcctct ttctgaacaa tgtccagctg ggtcccagcc ttacagagaa gctatgtttg      660

gaattagcaa acacaagcat tcggaatctg tctctgagta acagccagct gtccaccacc      720

agcaatacaa ctttcttggg actaaagtgg acaaatctca ctatgctcga tctttcctac      780

aacaacttaa atgtggttgg taacgattcc tttgcttggc ttccacaact agaatatttc      840

ttcctagagt ataataatat acagcatttg ttttctcact ctttgcacgg gcttttcaat      900

gtgaggtacc tgaatttgaa acggtctttt actaaacaaa gtatttccct tgcctcactc      960

cccaagattg atgatttttc ttttcagtgg ctaaaatgtt tggagcacct taacatggaa     1020

gataatgata ttccaggcat aaaaagcaat atgttcacag gattgataaa cctgaaatac     1080

ttaagtctat ccaactcctt tacaagtttg cgaactttga caaatgaaac atttgtatca     1140

cttgctcatt ctcccttaca catactcaac ctaaccaaga ataaaatctc aaaaatagag     1200

agtgatgctt tctcttggtt gggccaccta gaagtacttg acctgggcct taatgaaatt     1260

gggcaagaac tcacaggcca ggaatggaga ggtctagaaa atattttcga aatctatctt     1320

tcctacaaca agtacctgca gctgactagg aactcctttg ccttggtccc aagccttcaa     1380

cgactgatgc tccgaagggt ggcccttaaa aatgtggata gctctccttc accattccag     1440

cctcttcgta acttgaccat tctggatcta agcaacaaca acatagccaa cataaatgat     1500

gacatgttgg agggtcttga gaaactagaa attctcgatt tgcagcataa caacttagca     1560

cggctctgga aacacgcaaa ccctggtggt cccatttatt tcctaaaggg tctgtctcac     1620

ctccacatcc ttaacttgga gtccaacggc tttgacgaga tcccagttga ggtcttcaag     1680

gatttatttg aactaaagat catcgattta ggattgaata atttaaacac acttccagca     1740

tctgtcttta ataatcaggt gtctctaaag tcattgaacc ttcagaagaa tctcataaca     1800

tccgttgaga agaaggtttt cgggccagct ttcaggaacc tgactgagtt agatatgcgc     1860

tttaatccct ttgattgcac gtgtgaaagt attgcctggt ttgttaattg gattaacgag     1920

acccatacca acatccctga gctgtcaagc cactaccttt gcaacactcc acctcactat     1980

catgggttcc cagtgagact ttttgataca tcatcttgca aagacagtgc cccctttgaa     2040

ctc                                                                   2043


<210>  4360
<211>  1824
<212>  DNA
<213>  Homo Sapiens

<400>  4360
gaaagctggg agccctgcgt ggaggtggtt cctaatatta cttatcaatg catggagctg       60

aatttctaca aaatccccga caacctcccc ttctcaacca agaacctgga cctgagcttt      120

aatcccctga ggcatttagg cagctatagc ttcttcagtt tcccagaact gcaggtgctg      180

gatttatcca ggtgtgaaat ccagacaatt gaagatgggg catatcagag cctaagccac      240

ctctctacct taatattgac aggaaacccc atccagagtt tagccctggg agccttttct      300

ggactatcaa gtttacagaa gctggtggct gtggagacaa atctagcatc tctagagaac      360

ttccccattg gacatctcaa aactttgaaa gaacttaatg tggctcacaa tcttatccaa      420

tctttcaaat tacctgagta tttttctaat ctgaccaatc tagagcactt ggacctttcc      480

agcaacaaga ttcaaagtat ttattgcaca gacttgcggg ttctacatca aatgccccta      540

ctcaatctct ctttagacct gtccctgaac cctatgaact ttatccaacc aggtgcattt      600

aaagaaatta ggcttcataa gctgacttta agaaataatt ttgatagttt aaatgtaatg      660

aaaacttgta ttcaaggtct ggctggttta gaagtccatc gtttggttct gggagaattt      720

agaaatgaag gaaacttgga aaagtttgac aaatctgctc tagagggcct gtgcaatttg      780

accattgaag aattccgatt agcatactta gactactacc tcgatgatat tattgactta      840

tttaattgtt tgacaaatgt ttcttcattt tccctggtga gtgtgactat tgaaagggta      900

aaagactttt cttataattt cggatggcaa catttagaat tagttaactg taaatttgga      960

cagtttccca cattgaaact caaatctctc aaaaggctta ctttcacttc caacaaaggt     1020

gggaatgctt tttcagaagt tgatctacca agccttgagt ttctagatct cagtagaaat     1080

ggcttgagtt tcaaaggttg ctgttctcaa agtgattttg ggacaaccag cctaaagtat     1140

ttagatctga gcttcaatgg tgttattacc atgagttcaa acttcttggg cttagaacaa     1200

ctagaacatc tggatttcca gcattccaat ttgaaacaaa tgagtgagtt ttcagtattc     1260

ctatcactca gaaacctcat ttaccttgac atttctcata ctcacaccag agttgctttc     1320

aatggcatct tcaatggctt gtccagtctc gaagtcttga aaatggctgg caattctttc     1380

caggaaaact tccttccaga tatcttcaca gagctgagaa acttgacctt cctggacctc     1440

tctcagtgtc aactggagca gttgtctcca acagcattta actcactctc cagtcttcag     1500

gtactaaata tgagccacaa caacttcttt tcattggata cgtttcctta taagtgtctg     1560

aactccctcc aggttcttga ttacagtctc aatcacataa tgacttccaa aaaacaggaa     1620

ctacagcatt ttccaagtag tctagctttc ttaaatctta ctcagaatga ctttgcttgt     1680

acttgtgaac accagagttt cctgcaatgg atcaaggacc agaggcagct cttggtggaa     1740

gttgaacgaa tggaatgtgc aacaccttca gataagcagg gcatgcctgt gctgagtttg     1800

aatatcacct gtcagatgaa taag                                            1824


<210>  4361
<211>  1857
<212>  DNA
<213>  Homo Sapiens

<400>  4361
attccttcct gctcctttga tggccgaata gccttttatc gtttctgcaa cctcacccag       60

gtcccccagg tcctcaacac cactgagagg ctcctgctga gcttcaacta tatcaggaca      120

gtcactgctt catccttccc ctttctggaa cagctgcagc tgctggagct cgggagccag      180

tataccccct tgactattga caaggaggcc ttcagaaacc tgcccaacct tagaatcttg      240

gacctgggaa gtagtaagat atacttcttg catccagatg cttttcaggg actgttccat      300

ctgtttgaac ttagactgta tttctgtggt ctctctgatg ctgtattgaa agatggttat      360

ttcagaaatt taaaggcttt aactcgcttg gatctatcca aaaatcagat tcgtagcctt      420

taccttcatc cttcatttgg gaagttgaat tccttaaagt ccatagattt ttcctccaac      480

caaatattcc ttgtatgtga acatgagctc gagcccctac aagggaaaac gctctccttt      540

tttagcctcg cagctaatag cttgtatagc agagtctcag tggactgggg aaaatgtatg      600

aacccattca gaaacatggt gctggagata ctagatgttt ctggaaatgg ctggacagtg      660

gacatcacag gaaactttag caatgccatc agcaaaagcc aggccttctc tttgattctt      720

gcccaccaca tcatgggtgc cgggtttggc ttccataaca tcaaagatcc tgaccagaac      780

acatttgctg gcctggccag aagttcagtg agacacctgg atctttcaca tgggtttgtc      840

ttctccctga actcacgagt ctttgagaca ctcaaggatt tgaaggttct gaaccttgcc      900

tacaacaaga taaataagat tgcagatgaa gcattttacg gacttgacaa cctccaagtt      960

ctcaatttgt catataacct tctgggggaa ctttacagtt cgaatttcta tggactacct     1020

aaggtagcct acattgattt gcaaaagaat cacattgcaa taattcaaga ccaaacattc     1080

aaattcctgg aaaaattaca gaccttggat ctccgagaca atgctcttac aaccattcat     1140

tttattccaa gcatacccga tatcttcttg agtggcaata aactagtgac tttgccaaag     1200

atcaacctta cagcgaacct catccactta tcagaaaaca ggctagaaaa tctagatatt     1260

ctctactttc tcctacgggt acctcatctc cagattctca ttttaaatca aaatcgcttc     1320

tcctcctgta gtggagatca aaccccttca gagaatccca gcttagaaca gcttttcctt     1380

ggagaaaata tgttgcaact tgcctgggaa actgagctct gttgggatgt ttttgaggga     1440

ctttctcatc ttcaagttct gtatttgaat cataactatc ttaattccct tccaccagga     1500

gtatttagcc atctgactgc attaagggga ctaagcctca actccaacag gctgacagtt     1560

ctttctcaca atgatttacc tgctaattta gagatcctgg acatatccag gaaccagctc     1620

ctagctccta atcctgatgt atttgtatca cttagtgtct tggatataac tcataacaag     1680

ttcatttgtg aatgtgaact tagcactttt atcaattggc ttaatcacac caatgtcact     1740

atagctgggc ctcctgcaga catatattgt gtgtaccctg actcgttctc tggggtttcc     1800

ctcttctctc tttccacgga aggttgtgat gaagaggaag tcttaaagtc cctaaag        1857


<210>  4362
<211>  1347
<212>  DNA
<213>  Homo Sapiens

<400>  4362
aatgaatttg cagtagacaa gtcaaaaaga ggtcttattc atgttccaaa agacctaccg       60

ctgaaaacca aagtcttaga tatgtctcag aactacatcg ctgagcttca ggtctctgac      120

atgagctttc tatcagagtt gacagttttg agactttccc ataacagaat ccagctactt      180

gatttaagtg ttttcaagtt caaccaggat ttagaatatt tggatttatc tcataatcag      240

ttgcaaaaga tatcctgcca tcctattgtg agtttcaggc atttagatct ctcattcaat      300

gatttcaagg ccctgcccat ctgtaaggaa tttggcaact tatcacaact gaatttcttg      360

ggattgagtg ctatgaagct gcaaaaatta gatttgctgc caattgctca cttgcatcta      420

agttatatcc ttctggattt aagaaattat tatataaaag aaaatgagac agaaagtcta      480

caaattctga atgcaaaaac ccttcacctt gtttttcacc caactagttt attcgctatc      540

caagtgaaca tatcagttaa tactttaggg tgcttacaac tgactaatat taaattgaat      600

gatgacaact gtcaagtttt cattaaattt ttatcagaac tcaccagagg tccaacctta      660

ctgaatttta ccctcaacca catagaaacg acttggaaat gcctggtcag agtctttcaa      720

tttctttggc ccaaacctgt ggaatatctc aatatttaca atttaacaat aattgaaagc      780

attcgtgaag aagattttac ttattctaaa acgacattga aagcattgac aatagaacat      840

atcacgaacc aagtttttct gttttcacag acagctttgt acaccgtgtt ttctgagatg      900

aacattatga tgttaaccat ttcagataca ccttttatac acatgctgtg tcctcatgca      960

ccaagcacat tcaagttttt gaactttacg cagaacgttt tcacagatag tatttttgaa     1020

aaatgttcca cgttagttaa attggagaca cttatctttg ttttgtctcc caactttgtc     1080

cagagtgagt ggtgccatta cgaactctat tttgcccatc acaatctctt tcatgaagga     1140

tctaataact taatcctcat cttactggaa cccattccac agaacagcat tcccaacaag     1200

taccacaagc tgaaggctct catgacgcag cggacttatt tgcagtggcc caaggagaaa     1260

agcaaacgtg ggctcttttg ggctaacatt agagccgctt ttaatatgaa attaacacta     1320

gtcactgaaa acaatgatgt gaaatct                                         1347


<210>  4363
<211>  2439
<212>  DNA
<213>  Homo Sapiens

<400>  4363
gctagatggt ttcctaaaac tctgccctgt gatgtcactc tggatgttcc aaagaaccat       60

gtgatcgtgg actgcacaga caagcatttg acagaaattc ctggaggtat tcccacgaac      120

accacgaacc tcaccctcac cattaaccac ataccagaca tctccccagc gtcctttcac      180

agactggacc atctggtaga gatcgatttc agatgcaact gtgtacctat tccactgggg      240

tcaaaaaaca acatgtgcat caagaggctg cagattaaac ccagaagctt tagtggactc      300

acttatttaa aatcccttta cctggatgga aaccagctac tagagatacc gcagggcctc      360

ccgcctagct tacagcttct cagccttgag gccaacaaca tcttttccat cagaaaagag      420

aatctaacag aactggccaa catagaaata ctctacctgg gccaaaactg ttattatcga      480

aatccttgtt atgtttcata ttcaatagag aaagatgcct tcctaaactt gacaaagtta      540

aaagtgctct ccctgaaaga taacaatgtc acagccgtcc ctactgtttt gccatctact      600

ttaacagaac tatatctcta caacaacatg attgcaaaaa tccaagaaga tgattttaat      660

aacctcaacc aattacaaat tcttgaccta agtggaaatt gccctcgttg ttataatgcc      720

ccatttcctt gtgcgccgtg taaaaataat tctcccctac agatccctgt aaatgctttt      780

gatgcgctga cagaattaaa agttttacgt ctacacagta actctcttca gcatgtgccc      840

ccaagatggt ttaagaacat caacaaactc caggaactgg atctgtccca aaacttcttg      900

gccaaagaaa ttggggatgc taaatttctg cattttctcc ccagcctcat ccaattggat      960

ctgtctttca attttgaact tcaggtctat cgtgcatcta tgaatctatc acaagcattt     1020

tcttcactga aaagcctgaa aattctgcgg atcagaggat atgtctttaa agagttgaaa     1080

agctttaacc tctcgccatt acataatctt caaaatcttg aagttcttga tcttggcact     1140

aactttataa aaattgctaa cctcagcatg tttaaacaat ttaaaagact gaaagtcata     1200

gatctttcag tgaataaaat atcaccttca ggagattcaa gtgaagttgg cttctgctca     1260

aatgccagaa cttctgtaga aagttatgaa ccccaggtcc tggaacaatt acattatttc     1320

agatatgata agtatgcaag gagttgcaga ttcaaaaaca aagaggcttc tttcatgtct     1380

gttaatgaaa gctgctacaa gtatgggcag accttggatc taagtaaaaa tagtatattt     1440

tttgtcaagt cctctgattt tcagcatctt tctttcctca aatgcctgaa tctgtcagga     1500

aatctcatta gccaaactct taatggcagt gaattccaac ctttagcaga gctgagatat     1560

ttggacttct ccaacaaccg gcttgattta ctccattcaa cagcatttga agagcttcac     1620

aaactggaag ttctggatat aagcagtaat agccattatt ttcaatcaga aggaattact     1680

catatgctaa actttaccaa gaacctaaag gttctgcaga aactgatgat gaacgacaat     1740

gacatctctt cctccaccag caggaccatg gagagtgagt ctcttagaac tctggaattc     1800

agaggaaatc acttagatgt tttatggaga gaaggtgata acagatactt acaattattc     1860

aagaatctgc taaaattaga ggaattagac atctctaaaa attccctaag tttcttgcct     1920

tctggagttt ttgatggtat gcctccaaat ctaaagaatc tctctttggc caaaaatggg     1980

ctcaaatctt tcagttggaa gaaactccag tgtctaaaga acctggaaac tttggacctc     2040

agccacaacc aactgaccac tgtccctgag agattatcca actgttccag aagcctcaag     2100

aatctgattc ttaagaataa tcaaatcagg agtctgacga agtattttct acaagatgcc     2160

ttccagttgc gatatctgga tctcagctca aataaaatcc agatgatcca aaagaccagc     2220

ttcccagaaa atgtcctcaa caatctgaag atgttgcttt tgcatcataa tcggtttctg     2280

tgcacctgtg atgctgtgtg gtttgtctgg tgggttaacc atacagaggt gactattcct     2340

tacctggcca cagatgtgac ttgtgtgggg ccaggagcac acaagggcca aagtgtgatc     2400

tccctggatc tgtacacctg tgagttagat ctgactaac                            2439


<210>  4364
<211>  2403
<212>  DNA
<213>  Homo Sapiens

<400>  4364
gaagaaaatt tttctagaag ctatccttgt gatgagaaaa agcaaaatga ctcagttatt       60

gcagagtgca gcaatcgtcg actacaggaa gttccccaaa cggtgggcaa atatgtgaca      120

gaactagacc tgtctgataa tttcatcaca cacataacga atgaatcatt tcaagggctg      180

caaaatctca ctaaaataaa tctaaaccac aaccccaatg tacagcacca gaacggaaat      240

cccggtatac aatcaaatgg cttgaatatc acagacgggg cattcctcaa cctaaaaaac      300

ctaagggagt tactgcttga agacaaccag ttaccccaaa taccctctgg tttgccagag      360

tctttgacag aacttagtct aattcaaaac aatatataca acataactaa agagggcatt      420

tcaagactta taaacttgaa aaatctctat ttggcctgga actgctattt taacaaagtt      480

tgcgagaaaa ctaacataga agatggagta tttgaaacgc tgacaaattt ggagttgcta      540

tcactatctt tcaattctct ttcacacgtg ccacccaaac tgccaagctc cctacgcaaa      600

ctttttctga gcaacaccca gatcaaatac attagtgaag aagatttcaa gggattgata      660

aatttaacat tactagattt aagcgggaac tgtccgaggt gcttcaatgc cccatttcca      720

tgcgtgcctt gtgatggtgg tgcttcaatt aatatagatc gttttgcttt tcaaaacttg      780

acccaacttc gatacctaaa cctctctagc acttccctca ggaagattaa tgctgcctgg      840

tttaaaaata tgcctcatct gaaggtgctg gatcttgaat tcaactattt agtgggagaa      900

atagcctctg gggcattttt aacgatgctg ccccgcttag aaatacttga cttgtctttt      960

aactatataa aggggagtta tccacagcat attaatattt ccagaaactt ctctaaactt     1020

ttgtctctac gggcattgca tttaagaggt tatgtgttcc aggaactcag agaagatgat     1080

ttccagcccc tgatgcagct tccaaactta tcgactatca acttgggtat taattttatt     1140

aagcaaatcg atttcaaact tttccaaaat ttctccaatc tggaaattat ttacttgtca     1200

gaaaacagaa tatcaccgtt ggtaaaagat acccggcaga gttatgcaaa tagttcctct     1260

tttcaacgtc atatccggaa acgacgctca acagattttg agtttgaccc acattcgaac     1320

ttttatcatt tcacccgtcc tttaataaag ccacaatgtg ctgcttatgg aaaagcctta     1380

gatttaagcc tcaacagtat tttcttcatt gggccaaacc aatttgaaaa tcttcctgac     1440

attgcctgtt taaatctgtc tgcaaatagc aatgctcaag tgttaagtgg aactgaattt     1500

tcagccattc ctcatgtcaa atatttggat ttgacaaaca atagactaga ctttgataat     1560

gctagtgctc ttactgaatt gtccgacttg gaagttctag atctcagcta taattcacac     1620

tatttcagaa tagcaggcgt aacacatcat ctagaattta ttcaaaattt cacaaatcta     1680

aaagttttaa acttgagcca caacaacatt tatactttaa cagataagta taacctggaa     1740

agcaagtccc tggtagaatt agttttcagt ggcaatcgcc ttgacatttt gtggaatgat     1800

gatgacaaca ggtatatctc cattttcaaa ggtctcaaga atctgacacg tctggattta     1860

tcccttaata ggctgaagca catcccaaat gaagcattcc ttaatttgcc agcgagtctc     1920

actgaactac atataaatga taatatgtta aagtttttta actggacatt actccagcag     1980

tttcctcgtc tcgagttgct tgacttacgt ggaaacaaac tactcttttt aactgatagc     2040

ctatctgact ttacatcttc ccttcggaca ctgctgctga gtcataacag gatttcccac     2100

ctaccctctg gctttctttc tgaagtcagt agtctgaagc acctcgattt aagttccaat     2160

ctgctaaaaa caatcaacaa atccgcactt gaaactaaga ccaccaccaa attatctatg     2220

ttggaactac acggaaaccc ctttgaatgc acctgtgaca ttggagattt ccgaagatgg     2280

atggatgaac atctgaatgt caaaattccc agactggtag atgtcatttg tgccagtcct     2340

ggggatcaaa gagggaagag tattgtgagt ctggagctaa caacttgtgt ttcagatgtc     2400

act                                                                   2403


<210>  4365
<211>  2379
<212>  DNA
<213>  Homo Sapiens

<400>  4365
ctgggtacct tgcctgcctt cctaccctgt gagctccagc cccacggcct ggtgaactgc       60

aactggctgt tcctgaagtc tgtgccccac ttctccatgg cagcaccccg tggcaatgtc      120

accagccttt ccttgtcctc caaccgcatc caccacctcc atgattctga ctttgcccac      180

ctgcccagcc tgcggcatct caacctcaag tggaactgcc cgccggttgg cctcagcccc      240

atgcacttcc cctgccacat gaccatcgag cccagcacct tcttggctgt gcccaccctg      300

gaagagctaa acctgagcta caacaacatc atgactgtgc ctgcgctgcc caaatccctc      360

atatccctgt ccctcagcca taccaacatc ctgatgctag actctgccag cctcgccggc      420

ctgcatgccc tgcgcttcct attcatggac ggcaactgtt attacaagaa cccctgcagg      480

caggcactgg aggtggcccc gggtgccctc cttggcctgg gcaacctcac ccacctgtca      540

ctcaagtaca acaacctcac tgtggtgccc cgcaacctgc cttccagcct ggagtatctg      600

ctgttgtcct acaaccgcat cgtcaaactg gcgcctgagg acctggccaa tctgaccgcc      660

ctgcgtgtgc tcgatgtggg cggaaattgc cgccgctgcg accacgctcc caacccctgc      720

atggagtgcc ctcgtcactt cccccagcta catcccgata ccttcagcca cctgagccgt      780

cttgaaggcc tggtgttgaa ggacagttct ctctcctggc tgaatgccag ttggttccgt      840

gggctgggaa acctccgagt gctggacctg agtgagaact tcctctacaa atgcatcact      900

aaaaccaagg ccttccaggg cctaacacag ctgcgcaagc ttaacctgtc cttcaattac      960

caaaagaggg tgtcctttgc ccacctgtct ctggcccctt ccttcgggag cctggtcgcc     1020

ctgaaggagc tggacatgca cggcatcttc ttccgctcac tcgatgagac cacgctccgg     1080

ccactggccc gcctgcccat gctccagact ctgcgtctgc agatgaactt catcaaccag     1140

gcccagctcg gcatcttcag ggccttccct ggcctgcgct acgtggacct gtcggacaac     1200

cgcatcagcg gagcttcgga gctgacagcc accatggggg aggcagatgg aggggagaag     1260

gtctggctgc agcctgggga ccttgctccg gccccagtgg acactcccag ctctgaagac     1320

ttcaggccca actgcagcac cctcaacttc accttggatc tgtcacggaa caacctggtg     1380

accgtgcagc cggagatgtt tgcccagctc tcgcacctgc agtgcctgcg cctgagccac     1440

aactgcatct cgcaggcagt caatggctcc cagttcctgc cgctgaccgg tctgcaggtg     1500

ctagacctgt cccacaataa gctggacctc taccacgagc actcattcac ggagctacca     1560

cgactggagg ccctggacct cagctacaac agccagccct ttggcatgca gggcgtgggc     1620

cacaacttca gcttcgtggc tcacctgcgc accctgcgcc acctcagcct ggcccacaac     1680

aacatccaca gccaagtgtc ccagcagctc tgcagtacgt cgctgcgggc cctggacttc     1740

agcggcaatg cactgggcca tatgtgggcc gagggagacc tctatctgca cttcttccaa     1800

ggcctgagcg gtttgatctg gctggacttg tcccagaacc gcctgcacac cctcctgccc     1860

caaaccctgc gcaacctccc caagagccta caggtgctgc gtctccgtga caattacctg     1920

gccttcttta agtggtggag cctccacttc ctgcccaaac tggaagtcct cgacctggca     1980

ggaaaccagc tgaaggccct gaccaatggc agcctgcctg ctggcacccg gctccggagg     2040

ctggatgtca gctgcaacag catcagcttc gtggcccccg gcttcttttc caaggccaag     2100

gagctgcgag agctcaacct tagcgccaac gccctcaaga cagtggacca ctcctggttt     2160

gggcccctgg cgagtgccct gcaaatacta gatgtaagcg ccaaccctct gcactgcgcc     2220

tgtggggcgg cctttatgga cttcctgctg gaggtgcagg ctgccgtgcc cggtctgccc     2280

agccgggtga agtgtggcag tccgggccag ctccagggcc tcagcatctt tgcacaggac     2340

ctgcgcctct gcctggatga ggccctctcc tgggactgt                            2379


<210>  4366
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  4366
agacatgaga ttaagaacag ctttaagaat aattatgaaa aggctttgaa gcagtataac       60

tctacaggag attatagaag ccatgcagta gacaagatcc aaaatacgtt gcattgttgt      120

ggtgtcaccg attatagaga ttggacagat actaattatt actcagaaaa aggatttcct      180

aagagttgct gtaaacttga agattgtact ccacagagag atgcagacaa agtaaacaat      240

gaaggttgtt ttataaaggt gatgaccatt atagagtcag aa                         282


<210>  4367
<211>  873
<212>  DNA
<213>  Homo Sapiens

<400>  4367
tccaaccagc ccccgggtgg tggcggcggc agcggcgggg actgtcccgg cggcaaaggc       60

aagagcatca actgctcaga attaaatgtg agggagtctg acgtaagagt ttgtgatgag      120

tcatcatgta aatatggagg agtctgtaaa gaagatggag atggtttgaa atgtgcatgc      180

caatttcagt gccatacaaa ttatattcct gtctgtggat caaatgggga cacttatcaa      240

aatgaatgct ttctcagaag ggctgcttgt aagcaccaga aagagataac agtaatagca      300

agaggaccat gctactctga taatggatct ggatctggag aaggagaaga ggaagggtca      360

ggggcagaag ttcacagaaa acactccaag tgtggaccct gcaaatataa agctgagtgt      420

gatgaagatg cagaaaatgt tgggtgtgta tgtaatatag attgcagtgg atacagtttt      480

aatcctgtgt gtgcttctga tgggagttcc tataacaatc cctgttttgt tcgagaagca      540

tcttgtataa agcaagaaca aattgatata aggcatcttg gtcattgcac agatacagat      600

gacactagtt tgttgggaaa gaaagatgat ggactacaat atcgaccaga tgtgaaagat      660

gctagtgatc aaagagaaga tgtttatatt ggaaaccaca tgccttgccc tgaaaacctc      720

aatggttact gcatccatgg aaaatgtgaa ttcatctatt ctactcagaa ggcttcttgt      780

agatgtgaat ctggctacac tggacagcac tgtgaaaaga cagactttag tattctctat      840

gtagtgccaa gtaggcaaaa gctcactcat gtt                                   873


<210>  4368
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  4368
ttccctacct ccttaagtga ctgccaaacg cccaccggct ggaattgctc tggttatgat       60

gacagagaaa atgatctctt cctctgtgac accaacacct gtaaatttga tggggaatgt      120

ttaagaattg gagacactgt gacttgcgtc tgtcagttca agtgcaacaa tgactatgtg      180

cctgtgtgtg gctccaatgg ggagagctac cagaatgagt gttacctgcg acaggctgca      240

tgcaaacagc agagtgagat acttgtggtg tcagaaggat catgtgccac agatgcagga      300

tcaggatctg gagatggagt ccatgaaggc tctggagaaa ctagtcaaaa ggagacatcc      360

acctgtgata tttgccagtt tggtgcagaa tgtgacgaag atgccgagga tgtctggtgt      420

gtgtgtaata ttgactgttc tcaaaccaac ttcaatcccc tctgcgcttc tgatgggaaa      480

tcttatgata atgcatgcca aatcaaagaa gcatcgtgtc agaaacagga gaaaattgaa      540

gtcatgtctt tgggtcgatg tcaagataac acaactacaa ctactaagtc tgaagatggg      600

cattatgcaa gaacagatta tgcagagaat gctaacaaat tagaagaaag tgccagagaa      660

caccacatac cttgtccgga acattacaat ggcttctgca tgcatgggaa gtgtgagcat      720

tctatcaata tgcaggagcc atcttgcagg tgtgatgctg gttatactgg acaacactgt      780

gaaaaaaagg actacagtgt tctatacgtt gttcccggtc ctgtacgatt tcagtatgtc      840


<210>  4369
<211>  945
<212>  DNA
<213>  Homo Sapiens

<400>  4369
ggggtggccg caggcctgta tgaactcaat ctcaccaccg atagccctgc caccacggga       60

gcggtggtga ccatctcggc cagcctggtg gccaaggaca acggcagcct ggccctgccc      120

gctgacgccc acctctaccg cttccactgg atccacaccc cgctggtgct tactggcaag      180

atggagaagg gtctcagctc caccatccgt gtggtcggcc acgtgcccgg ggaattcccg      240

gtctctgtct gggtcactgc cgctgactgc tggatgtgcc agcctgtggc caggggcttt      300

gtggtcctcc ccatcacaga gttcctcgtg ggggaccttg ttgtcaccca gaacacttcc      360

ctaccctggc ccagctccta tctcactaag accgtcctga aagtctcctt cctcctccac      420

gacccgagca acttcctcaa gaccgccttg tttctctaca gctgggactt cggggacggg      480

acccagatgg tgactgaaga ctccgtggtc tattataact attccatcat cgggaccttc      540

accgtgaagc tcaaagtggt ggcggagtgg gaagaggtgg agccggatgc cacgagggct      600

gtgaagcaga agaccgggga cttctccgcc tcgctgaagc tgcaggaaac ccttagaggc      660

atccaagtgt tggggcccac cctaattcag accttccaaa agatgaccgt gaccttgaac      720

ttcctgggga gccctcctct gactgtgtgc tggcgtctca agcctgagtg cctcccgctg      780

gaggaagggg agtgccaccc tgtgtccgtg gccagcacag cgtacaacct gacccacacc      840

ttcagggacc ctggggacta ctgcttcagc atccgggccg agaatatcat cagcaagaca      900

catcagtacc acaagatcca ggtgtggccc tccagaatcc agccg                      945


<210>  4370
<211>  423
<212>  DNA
<213>  Homo Sapiens

<400>  4370
tcccagtact gcggccgcct tgaatactgg aacccagaca acaagtgctg cagcagctgc       60

ctgcaacgct tcgggccgcc cccctgcccg gactatgagt tccgggaaaa ctgcggactc      120

aatgaccacg gcgatttcgt aacgcccccg ttccgaaagt gttcttctgg gcagtgcaac      180

ccagacggcg cggagctatg tagcccctgc ggcggcggag ccgtgacccc tactcccgcc      240

gcgggcgggg gcagaacccc gtggcgctgc agagagaggc cggtccctgc caaggggcac      300

tgccccctca cacctggaaa cccaggcgcc cctagctccc aggagcgcag ctcaccagca      360

agttccattg cctggaggac ccctgagcct gtccctcagc aggcctggcc gaatttcctt      420

ccg                                                                    423


<210>  4371
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  4371
gagttggagc cacaaataga tggtcagacc tgggctgagc gggcacttcg ggagaatgaa       60

cgccacgcct tcacctgccg ggtggcaggg gggcctggca cccccagatt ggcctggtat      120

ctggatggac agctgcagga ggccagcacc tcaagactgc tgagcgtggg aggggaggcc      180

ttctctggag gcaccagcac cttcactgtc actgcccatc gggcccagca tgagctcaac      240

tgctctctgc aggaccccag aagtggccga tcagccaacg cctctgtcat ccttaatgtg      300

caattcaagc cagagattgc ccaagtcggc gccaagtacc aggaagctca gggcccaggc      360

ctcctggttg tcctgtttgc cctggtgcgt gccaacccgc cggccaatgt cacctggatc      420

gaccaggatg ggccagtgac tgtcaacacc tctgacttcc tggtgctgga tgcgcagaac      480

tacccctggc tcaccaacca cacggtgcag ctgcagctcc gcagcctggc acacaacctc      540

tcggtggtgg ccaccaatga cgtgggtgtc accagtgcgt cgcttccagc cccagggctt      600

ctggctaccc gggtggaa                                                    618


<210>  4372
<211>  1533
<212>  DNA
<213>  Homo Sapiens

<400>  4372
ggctacagcg ggaagagcga ggtggggctg gtgtccgagc acttctcaca ggccccgcag       60

aggctgtcct tctacagctg gtatggcagt gccaggctct tccgcttccg cgtgccccca      120

gatgctgtgc ttctacgctg gctcctgcag gtctcccggg agagcggcgc tgcctgcacc      180

gacgcggaga tcaccgtgca cttccgttcc ggcgcccctc cggtcatcaa cccgctgggc      240

accagcttcc cggacgacac cgcggtgcag ccctccttcc aggtcggggt gccgctgagc      300

accgcaccga gaagcaatgc ctccgtcaac gtttcccacc cggcccccgg ggactggttc      360

gtggccgccc acctgccccc ctcatcccag aagatcgagt tgaagggctt ggctcccacc      420

tgtgcctacg tcttccagcc tgaactgctg gtcacgcggg tggtcgagat ttccatcatg      480

gagccggacg tgccccttcc tcagaccctc ctctcccatc ccagctacct caaggtcttt      540

gtccccgatt acacgcggga gcttctgctg gagctgcggg actgcgtgtc caatgggagc      600

ctgggctgcc ccgtgcgtct caccgtgggc ccggtcaccc tgcctagcaa cttccagaag      660

gtgctcacct gcaccggtgc cccctggccc tgccgcctgc tgctgccctc accgccctgg      720

gaccggtggc tgcaagtgac agctgagagc ctggtggggc ccctcgggac agtggctttc      780

agtgctgtag ctgccctcac agcttgcagg ccacggagcg tgaccgtcca gccccttctg      840

cagagcagcc aaaaccagag cttcaatgcc tcctctggtc tgctgtcccc gagccccgac      900

caccaggacc tgggcaggag tggcagggtg gaccgcagcc ccttctgcct cacaaactac      960

ccagtcacgc gggaggacat ggacgtggtg tcggtgcact tccagcccct ggacagggtc     1020

tcggtgaggg tgtgttcgga cacgccctcc gtgatgcggc tgcgcctgaa caccggcatg     1080

gacagcgggg gttccctcac catctccctg cgggccaaca agacagagat gcggaacgag     1140

accgtcgtag tggcctgcgt gaatgctgcc tcgcccttcc ttggcttcaa tacttcgctc     1200

aactgcacca cagccttctt ccagggctac cctttgtctc tgagcgcctg gtctcgcagg     1260

gccaacctca tcatccccta cccagagaca gacaactggt acctctccct gcagctcatg     1320

tgccctgaga atgctgagga ctgtgagcag gctgtggtcc acgtggagac caccttgtac     1380

ctggtgccct gtttgaacga ttgtggaccc tatggccagt gcctcctgct ccgcagacac     1440

agctacctgt atgccagctg cagctgcaag gcaggctggc gtgggtggag ctgcacggac     1500

aacagcacag cccagacggt ggcccagcag agg                                  1533


<210>  4373
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  4373
atccctgaga agctgcaaga agctgtgggg aaagttatca tcaatgccac aacctgtact       60

gtcacctgtg gccttggcta taaggaggag accgtctgtg aggtgggccc tgatggagtg      120

agaaggaaat gtcagactcg gcgcttagaa tgtctgacca actggatctg tgggatgctc      180

catttcacca ttctcattgg caaggaattt gagcttagct gtctgagttc agacatcttg      240

gagtttggac aggaagcttt ccggttcacc tggagacttg ctcgaggtgt catctccact      300

gacgatgagg tcttcaaacc ctttcaagcc aactcccact ttgtgaagtt taaatatgct      360

caggagtatg actctgggac atatcgctgt gatgtgcagc tggtaaaaaa cttgagactc      420

gtcaagaggc tctattttgg gttgagggtc cttcctccta acttggtgaa tctgaatttc      480

catcagtcac ttactgagga tcagaagtta atagatgagg gattggaagt taatctggac      540

agctactcca agcctcacca cccaaagtgg aaaaagaagg tggcgtca                   588


<210>  4374
<211>  699
<212>  DNA
<213>  Homo Sapiens

<400>  4374
atgaacatgc cccagtccct gggcaaccag ccactgcccc cagaaccgcc atcccttgga       60

acccctgcgg aggggcctgg gaccacgtcc ccacccgagc actgctggcc agtgcgcccg      120

actctgcgca acgagctgga caccttctct gtccacttct acatcttctt tggcccaagt      180

gtggcccttc cccctgagcg cccagccgtg ttcgccatga ggctgttgcc agtgctggac      240

agtggaggcg tcctcagcct ggagctccag ctcaatgcga gctccgtgcg ccaggaaaac      300

gtgacggtgt ttggatgctt gactcacgag gtgcccttga gcctggggga tgcagcagtg      360

acctgttcca aagagtccct ggccggcttc ctcctctctg tcagtgccac caccagggtt      420

gccaggctgc gaatcccatt cccgcagacg gggacctggt tcctggccct ccgctccctg      480

tgcggggtgg ggcctcggtt cgtgcggtgc cgcaacgcga cggccgaggt gtggatgcgc      540

accttcctgt ccccatgcgt ggacgactgc gggccctacg gccagtgcaa gctgctgcgc      600

acacacaatt atctgtacgc agcctgcgag tgcaaggccg ggtggagagg ctggggctgc      660

accgacagtg cagatgcgct cacctatgga ttccagctg                             699


<210>  4375
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  4375
gttttaactg tgaatggtaa aactgagaac tatatcctgg atactacacc tggctcccaa       60

gcatctctga tatgtgctgt tcaaaaccac accagagagg aagaactgct ctggtaccga      120

gaggagggga gagtggattt gaaatctgga aacaaaatca attccagctc tgtctgtgtc      180

tcttccatca gtgaaaatga caacggaatc agctttacct gcaggctggg gagggatcag      240

tccgtgtccg tttcggtggt gctgaatgtt acttttcctc ctctcctaag tggaaacgac      300

ttccaaacag ttgaggaagg cagtaatgtg aagttggttt gcaatgtgaa agccaacccc      360

caggctcaaa tgatgtggta caaaaacagt agtctcctcg atttagagaa aagccgtcac      420

caaatccaac agacaagtga gtcttttcag ctgtcaatca ccaaagtcga gaagcctgac      480

aacggaacct acagttgtat tgcaaagtca tctctgaaaa cggagagctt ggactttcac      540

ctgattgtta aagataaaac tgtgggtgta cca                                   573


<210>  4376
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  4376
ctgagcgtgc agcaggggcc caacttgctg caggtgaggc agggcagtca ggcgaccctg       60

gtctgccagg tggaccaggc cacagcctgg gaacggctcc gtgttaagtg gacaaaggat      120

ggggccatcc tgtgtcaacc gtacatcacc aacggcagcc tcagcctggg ggtctgcggg      180

ccccagggac ggctctcctg gcaggcaccc agccatctca ccctgcagct ggaccctgtg      240

agcctcaacc acagcggggc gtacgtgtgc tgggcggccg tagagattcc tgagttggag      300

gaggctgagg gcaacataac aaggctcttt gtggacccag atgaccccac acagaacaga      360

aaccggatcg caagcttccc agga                                             384


<210>  4377
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  4377
gagccaccaa cccagaagcc caagaagatt gtaaatgcca agaaagatgt tgtgaacaca       60

aagatgtttg aggagctcaa gagccgtctg gacaccctgg cccaggaggt ggccctgctg      120

aaggagcagc aggccctgca gacggtctgc ctgaagggga ccaaggtgca catgaaatgc      180

tttctggcct tcacccagac gaagaccttc cacgaggcca gcgaggactg catctcgcgc      240

gggggcaccc tgagcacccc tcagactggc tcggagaacg acgccctgta tgagtacctg      300

cgccagagcg tgggcaacga ggccgagatc tggctgggcc tcaacgacat ggcggccgag      360

ggcacctggg tggacatgac cggcgcccgc atcgcctaca agaactggga gactgagatc      420

accgcgcaac ccgatggcgg caagaccgag aactgcgcgg tcctgtcagg cgcggccaac      480

ggcaagtggt tcgacaagcg ctgccgcgat cagctgccct acatctgcca gttcgggatc      540

gtg                                                                    543


<210>  4378
<211>  471
<212>  DNA
<213>  Homo Sapiens

<400>  4378
gtcagatcat cttctcgaac cccgagtgac aagcctgtag cccatgttgt agcaaaccct       60

caagctgagg ggcagctcca gtggctgaac cgccgggcca atgccctcct ggccaatggc      120

gtggagctga gagataacca gctggtggtg ccatcagagg gcctgtacct catctactcc      180

caggtcctct tcaagggcca aggctgcccc tccacccatg tgctcctcac ccacaccatc      240

agccgcatcg ccgtctccta ccagaccaag gtcaacctcc tctctgccat caagagcccc      300

tgccagaggg agaccccaga gggggctgag gccaagccct ggtatgagcc catctatctg      360

ggaggggtct tccagctgga gaagggtgac cgactcagcg ctgagatcaa tcggcccgac      420

tatctcgact ttgccgagtc tgggcaggtc tactttggga tcattgccct g               471


<210>  4379
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  4379
gcgagtggga cagaggcagc cgcggccaca cccagcaaag tgtggggctc ttccgcgggg       60

aggattgaac cacgaggcgg gggccgagga gcgctcccta cctccatggg acagcacgga      120

cccagtgccc gggcccgggc agggcgcgcc ccaggaccca ggccggcgcg ggaagccagc      180

cctcggctcc gggtccacaa gaccttcaag tttgtcgtcg tcggggtcct gctgcaggtc      240

gtacctagct cagctgcaac catcaaactt catgatcaat caattggcac acagcaatgg      300

gaacatagcc ctttgggaga gttgtgtcca ccaggatctc atagatcaga acatcctgga      360

gcctgtaacc ggtgcacaga gggtgtgggt tacaccaatg cttccaacaa tttgtttgct      420

tgcctcccat gtacagcttg taaatcagat gaagaagaga gaagtccctg caccacgacc      480

aggaacacag catgtcagtg caaaccagga actttccgga atgacaattc tgctgagatg      540

tgccggaagt gcagcagagg gtgccccaga gggatggtca aggtcaagga ttgtacgccc      600

tggagtgaca tcgagtgtgt ccacaaagaa tcaggcaatg gacataat                   648


<210>  4380
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  4380
atcacccaac aagacctagc tccccagcag agagcggccc cacaacaaaa gaggtccagc       60

ccctcagagg gattgtgtcc acctggacac catatctcag aagacggtag agattgcatc      120

tcctgcaaat atggacagga ctatagcact cactggaatg acctcctttt ctgcttgcgc      180

tgcaccaggt gtgattcagg tgaagtggag ctaagtccct gcaccacgac cagaaacaca      240

gtgtgtcagt gcgaagaagg caccttccgg gaagaagatt ctcctgagat gtgccggaag      300

tgccgcacag ggtgtcccag agggatggtc aaggtcggtg attgtacacc ctggagtgac      360

atcgaatgtg tccacaaaga atcaggtaca aagcacagtg gggaagcccc agctgtggag      420

gagacggtga cctccagccc agggactcct gcctctccct gttct                      465


<210>  4381
<211>  453
<212>  DNA
<213>  Homo Sapiens

<400>  4381
gccaccactg cccggcagga ggaagttccc cagcagacag tggccccaca gcaacagagg       60

cacagcttca agggggagga gtgtccagca ggatctcata gatcagaaca tactggagcc      120

tgtaacccgt gcacagaggg tgtggattac accaacgctt ccaacaatga accttcttgc      180

ttcccatgta cagtttgtaa atcagatcaa aaacataaaa gttcctgcac catgaccaga      240

gacacagtgt gtcagtgtaa agaaggcacc ttccggaatg aaaactcccc agagatgtgc      300

cggaagtgta gcaggtgccc tagtggggaa gtccaagtca gtaattgtac gtcctgggat      360

gatatccagt gtgttgaaga atttggtgcc aatgccactg tggaaacccc agctgctgaa      420

gagacaatga acaccagccc ggggactcct gcc                                   453


<210>  4382
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  4382
gccaccatcc cccggcagga cgaagttccc cagcagacag tggccccaca gcaacagagg       60

cgcagcctca aggaggagga gtgtccagca ggatctcata gatcagaata tactggagcc      120

tgtaacccgt gcacagaggg tgtggattac accattgctt ccaacaattt gccttcttgc      180

ctgctatgta cagtttgtaa atcaggtcaa acaaataaaa gttcctgtac cacgaccaga      240

gacaccgtgt gtcagtgtga aaaaggaagc ttccaggata aaaactcccc tgagatgtgc      300

cggacgtgta gaacagggtg tcccagaggg atggtcaagg tcagtaattg tacgccccgg      360

agtgacatca agtgcaaaaa tgaatcagct gccagttcca ctgggaaaac cccagcagcg      420

gaggagacag tgaccaccat cctggggatg cttgcctctc cctatcac                   468


<210>  4383
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  4383
atcgctcctc catgtaccag tgagaagcat tatgagcatc tgggacggtg ctgtaacaaa       60

tgtgaaccag gaaagtacat gtcttctaaa tgcactacta cctctgacag tgtatgtctg      120

ccctgtggcc cggatgaata cttggatagc tggaatgaag aagataaatg cttgctgcat      180

aaagtttgtg atacaggcaa ggccctggtg gccgtggtcg ccggcaacag cacgaccccc      240

cggcgctgcg cgtgcacggc tgggtaccac tggagccagg actgcgagtg ctgccgccgc      300

aacaccgagt gcgcgccggg cctgggcgcc cagcacccgt tgcagctcaa caaggacaca      360

gtgtgcaaac cttgccttgc aggctacttc tctgatgcct tttcctccac ggacaaatgc      420

agaccctgga ccaactgtac cttccttgga aagagagtag aacatcatgg gacagagaaa      480

tccgatgcgg tttgcagttc ttctctgcca gctagaaaac caccaaatga accccatgtt      540

tacttgccc                                                              549


<210>  4384
<211>  1140
<212>  DNA
<213>  Homo Sapiens

<400>  4384
gaaacgtttc ctccaaagta ccttcattat gacgaagaaa cctctcatca gctgttgtgt       60

gacaaatgtc ctcctggtac ctacctaaaa caacactgta cagcaaagtg gaagaccgtg      120

tgcgcccctt gccctgacca ctactacaca gacagctggc acaccagtga cgagtgtcta      180

tactgcagcc ccgtgtgcaa ggagctgcag tacgtcaagc aggagtgcaa tcgcacccac      240

aaccgcgtgt gcgaatgcaa ggaagggcgc taccttgaga tagagttctg cttgaaacat      300

aggagctgcc ctcctggatt tggagtggtg caagctggaa ccccagagcg aaatacagtt      360

tgcaaaagat gtccagatgg gttcttctca aatgagacgt catctaaagc accctgtaga      420

aaacacacaa attgcagtgt ctttggtctc ctgctaactc agaaaggaaa tgcaacacac      480

gacaacatat gttccggaaa cagtgaatca actcaaaaat gtggaataga tgttaccctg      540

tgtgaggagg cattcttcag gtttgctgtt cctacaaagt ttacgcctaa ctggcttagt      600

gtcttggtag acaatttgcc tggcaccaaa gtaaacgcag agagtgtaga gaggataaaa      660

cggcaacaca gctcacaaga acagactttc cagctgctga agttatggaa acatcaaaac      720

aaagaccaag atatagtcaa gaagatcatc caagatattg acctctgtga aaacagcgtg      780

cagcggcaca ttggacatgc taacctcacc ttcgagcagc ttcgtagctt gatggaaagc      840

ttaccgggaa agaaagtggg agcagaagac attgaaaaaa caataaaggc atgcaaaccc      900

agtgaccaga tcctgaagct gctcagtttg tggcgaataa aaaatggcga ccaagacacc      960

ttgaagggcc taatgcacgc actaaagcac tcaaagacgt accactttcc caaaactgtc     1020

actcagagtc taaagaagac catcaggttc cttcacagct tcacaatgta caaattgtat     1080

cagaagttat ttttagaaat gataggtaac caggtccaat cagtaaaaat aagctgctta     1140


<210>  4385
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4385
gagcaagcgc caggcaccgc cccctgctcc cgcggcagct cctggagcgc ggacctggac       60

aagtgcatgg actgcgcgtc ttgcagggcg cgaccgcaca gcgacttctg cctgggctgc      120

gctgcagcac ctcctgcccc cttccggctg ctttggccc                             159


<210>  4386
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4386
atgagtggcc tgggccggag caggcgaggt ggccggagcc gtgtggacca ggaggagcgc       60

tggtcactca gctgccgcaa ggagcaaggc aagttctatg accatctcct gagggactgc      120

atcagctgtg cctccatctg tggacagcac cctaagcaat gtgcatactt ctgtgagaac      180

aagctcagga gcccagtgaa ccttccacca gagctcagga gacagcggag tggagaagtt      240

gaaaacaatt cagacaactc gggaaggtac caaggattgg agcacagagg ctcagaagca      300

agtccagctc tcccggggct gaagctgagt gcagatcagg tggccctggt ctacagc         357


<210>  4387
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  4387
atgaggcgag ggccccggag cctgcggggc agggacgcgc cagcccccac gccctgcgtc       60

ccggccgagt gcttcgacct gctggtccgc cactgcgtgg cctgcgggct cctgcgcacg      120

ccgcggccga aaccggccgg ggccagcagc cctgcgccca ggacggcgct gcagccgcag      180

gagtcggtgg gcgcgggggc cggcgaggcg gcgctgcccc tgcccgggct gctc            234


<210>  4388
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  4388
ctgccgtcct gcaaggagga cgagtaccca gtgggctccg agtgctgccc caagtgcagt       60

ccaggttatc gtgtgaagga ggcctgcggg gagctgacgg gcacagtgtg tgaaccctgc      120

cctccaggca cctacattgc ccacctcaat ggcctaagca agtgtctgca gtgccaaatg      180

tgtgacccag ccatgggcct gcgcgcgagc cggaactgct ccaggacaga gaacgccgtg      240

tgtggctgca gcccaggcca cttctgcatc gtccaggacg gggaccactg cgccgcgtgc      300

cgcgcttacg ccacctccag cccgggccag agggtgcaga agggaggcac cgagagtcag      360

gacaccctgt gtcagaactg ccccccgggg accttgtctc ccaatgggac cctggaggaa      420

tgtcagcacc agaccaagtg cagctggctg gtgacgaagg ccggagctgg gaccagcagc      480

tcccactggg ta                                                          492


<210>  4389
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  4389
atgttgcaga tggctgggca gtgctcccaa aatgaatatt ttgacagttt gttgcatgct       60

tgcatacctt gtcaacttcg atgttcttct aatactcctc ctctaacatg tcagcgttat      120

tgtaatgcaa gtgtgaccaa ttcagtgaaa ggaacgaatg cg                         162


<210>  4390
<211>  423
<212>  DNA
<213>  Homo Sapiens

<400>  4390
gaatcaggag actgtagaca gcaagaattc agggatcggt ctggaaactg tgttccctgc       60

aaccagtgtg ggccaggcat ggagttgtct aaggaatgtg gcttcggcta tggggaggat      120

gcacagtgtg tgacgtgccg gctgcacagg ttcaaggagg actggggctt ccagaaatgc      180

aagccctgtc tggactgcgc agtggtgaac cgctttcaga aggcaaattg ttcagccacc      240

agtgatgcca tctgcgggga ctgcttgcca ggattttata ggaagacgaa acttgtcggc      300

tttcaagaca tggagtgtgt gccttgtgga gaccctcctc ctccttacga accgcactgt      360

gccagcaagg tcaacctcgt gaagatcgcg tccacggcct ccagcccacg ggacacggcg      420

ctg                                                                    423


<210>  4391
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  4391
tcaacaaccc tttggcagtg cccacctggg gaggagcccg acctggaccc agggcagggc       60

acattatgca ggccctgccc cccaggcacc ttctcagctg catggggctc cagcccatgc      120

cagccccatg cccgttgcag cctttggagg aggctggagg cccaggtggg catggcaact      180

cgagatacac tctgtggaga ctgctggcct gggtggtttg ggccttgggg ggttccccgc      240

gttccatgtc aaccatgttc ctgggcacct ctgggtactc atggctgtga tgagtggggg      300

cggcgggccc gacgtggcgt ggaggtggca gcaggggcca gcagcggtgg tgagacacgg      360

cagcctggga acggcacccg ggcaggtggc ccagaggaga cagccgccca g               411


<210>  4392
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  4392
gatagtgtgt gtccccaagg aaaatatatc caccctcaaa ataattcgat ttgctgtacc       60

aagtgccaca aaggaaccta cttgtacaat gactgtccag gcccggggca ggatacggac      120

tgcagggagt gtgagagcgg ctccttcacc gcttcagaaa accacctcag acactgcctc      180

agctgctcca aatgccgaaa ggaaatgggt caggtggaga tctcttcttg cacagtggac      240

cgggacaccg tgtgtggctg caggaagaac cagtaccggc attattggag tgaaaacctt      300

ttccagtgct tcaattgcag cctctgcctc aatgggaccg tgcacctctc ctgccaggag      360

aaacagaaca ccgtgtgcac ctgccatgca ggtttctttc taagagaaaa cgagtgtgtc      420

tcctgtagta actgtaagaa aagcctggag tgcacgaagt tgtgcctacc ccagattgag      480

aat                                                                    483


<210>  4393
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4393
ttgcccgccc aggtggcatt tacaccctac gccccggagc ccgggagcac atgccggctc       60

agagaatact atgaccagac agctcagatg tgctgcagca aatgctcgcc gggccaacat      120

gcaaaagtct tctgtaccaa gacctcggac accgtgtgtg actcctgtga ggacagcaca      180

tacacccagc tctggaactg ggttcccgag tgcttgagct gtggctcccg ctgtagctct      240

gaccaggtgg aaactcaagc ctgcactcgg gaacagaacc gcatctgcac ctgcaggccc      300

ggctggtact gcgcgctgag caagcaggag gggtgccggc tgtgcgcgcc gctgcgcaag      360

tgccgcccgg gcttcggcgt ggccagacca ggaactgaaa catcagacgt ggtgtgcaag      420

ccctgtgccc cggggacgtt ctccaacacg acttcatcca cggatatttg caggccccac      480

cagatctgta acgtggtggc catccctggg aatgcaagca tggatgcagt ctgcacgtcc      540

acgtccccca cccggagtat ggccccaggg gcagtacact taccccagcc agtgtccaca      600

cgatcccaac acacgcagcc aactccagaa cccagcactg ctccaagcac ctccttcctg      660

ctcccaatgg gccccagccc cccagctgaa gggagcactg gcgac                      705


<210>  4394
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  4394
cagccagaac agaaggcctc gaatctcatt ggcacatacc gccatgttga ccgtgccacc       60

ggccaggtgc taacctgtga caagtgtcca gcaggaacct atgtctctga gcattgtacc      120

aacacaagcc tgcgcgtctg cagcagttgc cctgtgggga cctttaccag gcatgagaat      180

ggcatagaga aatgccatga ctgtagtcag ccatgcccat ggccaatgat tgagaaatta      240

ccttgtgctg ccttgactga ccgagaatgc acttgcccac ctggcatgtt ccagtctaac      300

gctacctgtg ccccccatac ggtgtgtcct gtgggttggg gtgtgcggaa gaaagggaca      360

gagactgagg atgtgcggtg taagcagtgt gctcggggta ccttctcaga tgtgccttct      420

agtgtgatga aatgcaaagc atacacagac tgtctgagtc agaacctggt ggtgatcaag      480

ccggggacca aggagacaga caacgtctgt ggcacactcc cgtccttctc cagctccacc      540

tcaccttccc ctggcacagc catctttcca cgccctgagc acatggaaac ccatgaagtc      600

ccttcctcca cttatgttcc caaaggcatg aactcaacag aatccaactc ttctgcctct      660

gttagaccaa aggtactgag tagcatccag gaagggacag tccctgacaa cacaagctca      720

gcaaggggga aggaagacgt gaacaagacc ctcccaaacc ttcaggtagt caaccaccag      780

caaggccccc accacagaca catcctgaag ctgctgccgt ccatggaggc cactgggggc      840

gagaagtcca gcacgcccat caagggcccc aagaggggac atcctagaca gaacctacac      900

aagcattttg acatcaatga gcat                                             924


<210>  4395
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  4395
cagggcggca ctcgtagccc caggtgtgac tgtgccggtg acttccacaa gaagattggt       60

ctgttttgtt gcagaggctg cccagcgggg cactacctga aggccccttg cacggagccc      120

tgcggcaact ccacctgcct tgtgtgtccc caagacacct tcttggcctg ggagaaccac      180

cataattctg aatgtgcccg ctgccaggcc tgtgatgagc aggcctccca ggtggcgctg      240

gagaactgtt cagcagtggc cgacacccgc tgtggctgta agccaggctg gtttgtggag      300

tgccaggtca gccaatgtgt cagcagttca cccttctact gccaaccatg cctagactgc      360

ggggccctgc accgccacac acggctactc tgttcccgca gagatactga ctgtgggacc      420

tgcctgcctg gcttctatga acatggcgat ggctgcgtgt cctgccccac gagcaccctg      480

gggagctgtc cagagcgctg tgccgctgtc tgtggctgga ggcag                      525


<210>  4396
<211>  558
<212>  DNA
<213>  Homo Sapiens

<400>  4396
ctccactgtg tcggggacac ctaccccagc aacgaccggt gctgccacga gtgcaggcca       60

ggcaacggga tggtgagccg ctgcagccgc tcccagaaca cggtgtgccg tccgtgcggg      120

ccgggcttct acaacgacgt ggtcagctcc aagccgtgca agccctgcac gtggtgtaac      180

ctcagaagtg ggagtgagcg gaagcagctg tgcacggcca cacaggacac agtctgccgc      240

tgccgggcgg gcacccagcc cctggacagc tacaagcctg gagttgactg tgccccctgc      300

cctccagggc acttctcccc aggcgacaac caggcctgca agccctggac caactgcacc      360

ttggctggga agcacaccct gcagccggcc agcaatagct cggacgcaat ctgtgaggac      420

agggaccccc cagccacgca gccccaggag acccagggcc ccccggccag gcccatcact      480

gtccagccca ctgaagcctg gcccagaacc tcacagggac cctccacccg gcccgtggag      540

gtccccgggg gccgtgcg                                                    558


<210>  4397
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  4397
gaaccaccca ctgcatgcag agaaaaacag tacctaataa acagtcagtg ctgttctttg       60

tgccagccag gacagaaact ggtgagtgac tgcacagagt tcactgaaac ggaatgcctt      120

ccttgcggtg aaagcgaatt cctagacacc tggaacagag agacacactg ccaccagcac      180

aaatactgcg accccaacct agggcttcgg gtccagcaga agggcacctc agaaacagac      240

accatctgca cctgtgaaga aggctggcac tgtacgagtg aggcctgtga gagctgtgtc      300

ctgcaccgct catgctcgcc cggctttggg gtcaagcaga ttgctacagg ggtttctgat      360

accatctgcg agccctgccc agtcggcttc ttctccaatg tgtcatctgc tttcgaaaaa      420

tgtcaccctt ggacaagctg tgagaccaaa gacctggttg tgcaacaggc aggcacaaac      480

aagactgatg ttgtctgtgg tccccaggat cggctgaga                             519


<210>  4398
<211>  444
<212>  DNA
<213>  Homo Sapiens

<400>  4398
caagtgactg acatcaactc caagggattg gaattgagga agactgttac tacagttgag       60

actcagaact tggaaggcct gcatcatgat ggccaattct gccataagcc ctgtcctcca      120

ggtgaaagga aagctaggga ctgcacagtc aatggggatg aaccagactg cgtgccctgc      180

caagaaggga aggagtacac agacaaagcc catttttctt ccaaatgcag aagatgtaga      240

ttgtgtgatg aaggacatgg cttagaagtg gaaataaact gcacccggac ccagaatacc      300

aagtgcagat gtaaaccaaa ctttttttgt aactctactg tatgtgaaca ctgtgaccct      360

tgcaccaaat gtgaacatgg aatcatcaag gaatgcacac tcaccagcaa caccaagtgc      420

aaagaggaag gatccagatc taac                                             444


<210>  4399
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  4399
gtggcagaaa cacccaccta cccctggcgg gacgcagaga caggggagcg gctggtgtgc       60

gcccagtgcc ccccaggcac ctttgtgcag cggccgtgcc gccgagacag ccccacgacg      120

tgtggcccgt gtccaccgcg ccactacacg cagttctgga actacctgga gcgctgccgc      180

tactgcaacg tcctctgcgg ggagcgtgag gaggaggcac gggcttgcca cgccacccac      240

aaccgtgcct gccgctgccg caccggcttc ttcgcgcacg ctggtttctg cttggagcac      300

gcatcgtgtc cacctggtgc cggcgtgatt gccccgggca cccccagcca gaacacgcag      360

tgccagccgt gccccccagg caccttctca gccagcagct ccagctcaga gcagtgccag      420

ccccaccgca actgcacggc cctgggcctg gccctcaatg tgccaggctc ttcctcccat      480

gacaccctgt gcaccagctg cactggcttc cccctcagca ccagggtacc aggagctgag      540

gagtgtgagc gtgccgtcat cgactttgtg gctttccagg acatctccat caagaggctg      600

cagcggctgc tgcaggccct cgaggccccg gagggctggg gtccgacacc aagggcgggc      660

cgcgcggcct tgcagctgaa gctgcgtcgg cggctcacgg agctcctggg ggcgcaggac      720

ggggcgctgc tggtgcggct gctgcaggcg ctgcgcgtgg ccaggatgcc cgggctggag      780

cggagcgtcc gtgagcgctt cctccctgtg cac                                   813


<210>  4400
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  4400
gctactccag cccccaagag ctgcccagag aggcactact gggctcaggg aaagctgtgc       60

tgccagatgt gtgagccagg aacattcctc gtgaaggact gtgaccagca tagaaaggct      120

gctcagtgtg atccttgcat accgggggtc tccttctctc ctgaccacca cacccggccc      180

cactgtgaga gctgtcggca ctgtaactct ggtcttctcg ttcgcaactg caccatcact      240

gccaatgctg agtgtgcctg tcgcaatggc tggcagtgca gggacaagga gtgcaccgag      300

tgtgatcctc ttccaaaccc ttcgctgacc gctcggtcgt ctcaggccct gagcccacac      360

cctcagccca cccacttacc ttatgtcagt gagatgctgg aggccaggac agctgggcac      420

atgcagactc tggctgactt caggcagctg cctgcccgga ctctctctac ccactggcca      480

ccccaaagat ccctgtgcag ctccgatttt attcgc                                516


<210>  4401
<211>  1083
<212>  DNA
<213>  Homo Sapiens

<400>  4401
tttccgcagg accgtccatt cgaggatact tgtcacggga atccatcaca ctactacgat       60

aaagcggtac gtaggtgttg ttaccgttgc cccatgggtt tatttcctac ccagcaatgc      120

ccccaacgtc caacagactg cagaaaacaa tgtgagccag attactactt agatgaagca      180

gaccgttgca ccgcctgtgt aacctgtagc cgtgatgacc tagtggagaa gaccccctgc      240

gcgtggaact cctcacgtgt ctgcgaatgc agacccggaa tgttttgctc aacatccgcg      300

gttaactctt gtgcaagatg cttcttccat agtgtatgtc ccgccggcat gattgttaag      360

tttccgggaa ctgcgcaaaa gaacacagtt tgcgaaccag ccagtccggg ggtgtctcca      420

gcttgcgctt caccagaaaa ttgcaaagag ccctcttcag gcacgatacc ccaggcaaaa      480

cctactcctg tctccccagc aaccagcagc gcctcaacta tgcccgtcag gggtggtaca      540

agactggccc aggaagcagc ttccaagtta actagagccc cggacagccc cagcagtgtg      600

ggtagaccgt caagcgatcc gggattgtcc ccgacccagc cgtgtcccga gggcagcggt      660

gattgccgta agcagtgcga gcctgattac taccttgatg aagcagggcg ttgtacggct      720

tgcgtgtcat gctcaaggga tgaccttgtt gaaaagacgc cctgcgcttg gaatagttca      780

cgtacatgcg agtgcagacc tggcatgata tgcgcaacca gcgcaacaaa ctcatgtgcg      840

aggtgtgtgc cttatccgat ctgcgcagca gaaaccgtca ccaaaccaca ggacatggct      900

gaaaaggaca caacattcga agcgccaccc ttaggaactc agccggactg caacccaacg      960

cctgagaatg gagaagcacc agctagtaca tcaccgacac aaagtctttt ggtcgactcc     1020

caagcgagta agacgctgcc tatacccacc tccgctcccg ttgccctgtc cagtactggt     1080

aag                                                                   1083


<210>  4402
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  4402
ttgcaggatc cttgtagtaa ctgcccagct ggtacattct gtgataataa caggaatcag       60

atttgcagtc cctgtcctcc aaatagtttc tccagcgcag gtggacaaag gacctgtgac      120

atatgcaggc agtgtaaagg tgttttcagg accaggaagg agtgttcctc caccagcaat      180

gcagagtgtg actgcactcc agggtttcac tgcctggggg caggatgcag catgtgtgaa      240

caggattgta aacaaggtca agaactgaca aaaaaaggtt gtaaagactg ttgctttggg      300

acatttaacg atcagaaacg tggcatctgt cgaccctgga caaactgttc tttggatgga      360

aagtctgtgc ttgtgaatgg gacgaaggag agggacgtgg tctgtggacc atctccagcc      420

gacctctctc cgggagcatc ctctgtgacc ccgcctgccc ctgcgagaga gccaggacac      480

tctccgcag                                                              489


<210>  4403
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  4403
accaacgagc tgaagcagat gcaggacaag tactccaaaa gtggcattgc ttgtttctta       60

aaagaagatg acagttattg ggaccccaat gacgaagaga gtatgaacag cccctgctgg      120

caagtcaagt ggcaactccg tcagctcgtt agaaagatga ttttgagaac ctctgaggaa      180

accatttcta cagttcaaga aaagcaacaa aatatttctc ccctagtgag agaaagaggt      240

cctcagagag tagcagctca cataactggg accagaggaa gaagcaacac attgtcttct      300

ccaaactcca agaatgaaaa ggctctgggc cgcaaaataa actcctggga atcatcaagg      360

agtgggcatt cattcctgag caacttgcac ttgaggaatg gtgaactggt catccatgaa      420

aaagggtttt actacatcta ttcccaaaca tactttcgat ttcaggagga aataaaagaa      480

aacacaaaga acgacaaaca aatggtccaa tatatttaca aatacacaag ttatcctgac      540

cctatattgt tgatgaaaag tgctagaaat agttgttggt ctaaagatgc agaatatgga      600

ctctattcca tctatcaagg gggaatattt gagcttaagg aaaatgacag aatttttgtt      660

tctgtaacaa atgagcactt gatagacatg gaccatgaag ccagtttttt cggggccttt      720

ttagttggc                                                              729


<210>  4404
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  4404
atcagagcag agaaagcgat ggtggatggc tcatggttag atctggccaa gaggagcaag       60

cttgaagctc agccttttgc tcatctcact attaatgcca ccgacatccc atctggttcc      120

cataaagtga gtctgtcctc ttggtaccat gatcggggtt gggccaagat ctccaacatg      180

acttttagca atggaaaact aatagttaat caggatggct tttattacct gtatgccaac      240

atttgctttc gacatcatga aacttcagga gacctagcta cagagtatct tcaactaatg      300

gtgtacgtca ctaaaaccag catcaaaatc ccaagttctc ataccctgat gaaaggagga      360

agcaccaagt attggtcagg gaattctgaa ttccattttt attccataaa cgttggtgga      420

ttttttaagt tacggtctgg agaggaaatc agcatcgagg tctccaaccc ctccttactg      480

gatccggatc aggatgcaac atactttggg gcttttaaag ttcgagatat agat            534


<210>  4405
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  4405
agtgcaccta aaggccggaa aacacgggct cgaagagcga tcgcagccca ttatgaagtt       60

catccacgac ctggacagga cggagcgcag gcaggtgtgg acgggacagt gagtggctgg      120

gaggaagcca gaatcaacag ctccagccct ctgcgctaca accgccagat cggggagttt      180

atagtcaccc gggctgggct ctactacctg tactgtcagg tgcactttga tgaggggaag      240

gctgtctacc tgaagctgga cttgctggtg gatggtgtgc tggccctgcg ctgcctggag      300

gaattctcag ccactgcggc gagttccctc gggccccagc tccgcctctg ccaggtgtct      360

gggctgttgg ccctgcggcc agggtcctcc ctgcggatcc gcaccctccc ctgggcccat      420

ctcaaggctg cccccttcct cacctacttc ggactcttcc aggttcac                   468


<210>  4406
<211>  438
<212>  DNA
<213>  Homo Sapiens

<400>  4406
gcagtgctca cccaaaaaca gaagaagcag cactctgtcc tgcacctggt tcccattaac       60

gccacctcca aggatgactc cgatgtgaca gaggtgatgt ggcaaccagc tcttaggcgt      120

gggagaggcc tacaggccca aggatatggt gtccgaatcc aggatgctgg agtttatctg      180

ctgtatagcc aggtcctgtt tcaagacgtg actttcacca tgggtcaggt ggtgtctcga      240

gaaggccaag gaaggcagga gactctattc cgatgtataa gaagtatgcc ctcccacccg      300

gaccgggcct acaacagctg ctatagcgca ggtgtcttcc atttacacca aggggatatt      360

ctgagtgtca taattccccg ggcaagggcg aaacttaacc tctctccaca tggaaccttc      420

ctggggtttg tgaaactg                                                    438


<210>  4407
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  4407
gccgttcagg gtccagaaga aacagtcact caagactgct tgcaactgat tgcagacagt       60

gaaacaccaa ctatacaaaa aggatcttac acatttgttc catggcttct cagctttaaa      120

aggggaagtg ccctagaaga aaaagagaat aaaatattgg tcaaagaaac tggttacttt      180

tttatatatg gtcaggtttt atatactgat aagacctacg ccatgggaca tctaattcag      240

aggaagaagg tccatgtctt tggggatgaa ttgagtctgg tgactttgtt tcgatgtatt      300

caaaatatgc ctgaaacact acccaataat tcctgctatt cagctggcat tgcaaaactg      360

gaagaaggag atgaactcca acttgcaata ccaagagaaa atgcacaaat atcactggat      420

ggagatgtca cattttttgg tgcattgaaa ctgctg                                456


<210>  4408
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  4408
caagagcgaa ggtctcacga ggtcaaccca gcagcgcatc tcacaggggc caactccagc       60

ttgaccggca gcggggggcc gctgttatgg gagactcagc tgggcctggc cttcctgagg      120

ggcctcagct accacgatgg ggcccttgtg gtcaccaaag ctggctacta ctacatctac      180

tccaaggtgc agctgggcgg tgtgggctgc ccgctgggcc tggccagcac catcacccac      240

ggcctctaca agcgcacacc ccgctacccc gaggagctgg agctgttggt cagccagcag      300

tcaccctgcg gacgggccac cagcagctcc cgggtctggt gggacagcag cttcctgggt      360

ggtgtggtac acctggaggc tggggagaag gtggtcgtcc gtgtgctgga tgaacgcctg      420

gttcgactgc gtgatggtac ccggtcttac ttcggggctt tcatggtg                   468


<210>  4409
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  4409
ctaaaaggac aggagtttgc accttcacat cagcaagttt atgcacctct tagagcagac       60

ggagataagc caagggcaca cctgacagtt gtgagacaaa ctcccacaca gcactttaaa      120

aatcagttcc cagctctgca ctgggaacat gaactaggcc tggccttcac caagaaccga      180

atgaactata ccaacaaatt cctgctgatc ccagagtcgg gagactactt catttactcc      240

caggtcacat tccgtgggat gacctctgag tgcagtgaaa tcagacaagc aggccgacca      300

aacaagccag actccatcac tgtggtcatc accaaggtaa cagacagcta ccctgagcca      360

acccagctcc tcatggggac caagtctgtg tgcgaagtag gtagcaactg gttccagccc      420

atctacctcg gagccatgtt ctccttgcaa gaaggggaca agctaatggt gaacgtcagt      480

gacatctctt tggtggatta cacaaaagaa gataaaacct tctttggagc cttcttacta      540


<210>  4410
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  4410
caattagaga ctgctaagga gccctgtatg gctaagtttg gaccattacc ctcaaaatgg       60

caaatggcat cttctgaacc tccttgcgtg aataaggtgt ctgactggaa gctggagata      120

cttcagaatg gcttatattt aatttatggc caagtggctc ccaatgcaaa ctacaatgat      180

gtagctcctt ttgaggtgcg gctgtataaa aacaaagaca tgatacaaac tctaacaaac      240

aaatctaaaa tccaaaatgt aggagggact tatgaattgc atgttgggga caccatagac      300

ttgatattca actctgagca tcaggttcta aaaaataata catactgggg tatcatttta      360

ctagcaaatc cccaattcat ctcc                                             384


<210>  4411
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  4411
atggtatcac atcggtatcc tcgaattcaa agtatcaaag tacaatttac cgaatataag       60

aaggagaaag gtttcatcct cacttcccaa aaggaggatg aaatcatgaa ggtgcagaac      120

aactcagtca tcatcaactg tgatgggttt tatctcatct ccctgaaggg ctacttctcc      180

caggaagtca acattagcct tcattaccag aaggatgagg agcccctctt ccaactgaag      240

aaggtcaggt ctgtcaactc cttgatggtg gcctctctga cttacaaaga caaagtctac      300

ttgaatgtga ccactgacaa tacctccctg gatgacttcc atgtgaatgg cggagaactg      360

attcttatcc atcaaaatcc tggtgaattc tgtgtcctt                             399


<210>  4412
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  4412
caaataggcc accccagtcc accccctgaa aaaaaggagc tgaggaaagt ggcccattta       60

acaggcaagt ccaactcaag gtccatgcct ctggaatggg aagacaccta tggaattgtc      120

ctgctttctg gagtgaagta taagaagggt ggccttgtga tcaatgaaac tgggctgtac      180

tttgtatatt ccaaagtata cttccggggt caatcttgca acaacctgcc cctgagccac      240

aaggtctaca tgaggaactc taagtatccc caggatctgg tgatgatgga ggggaagatg      300

atgagctact gcactactgg gcagatgtgg gcccgcagca gctacctggg ggcagtgttc      360

aatcttacca gtgctgatca tttatatgtc aacgtatctg agctctctct ggtcaatttt      420

gaggaatctc agacgttttt cggcttatat aagctc                                456


<210>  4413
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  4413
cagaggacgg actccattcc caactcacct gacaacgtcc ccctcaaagg aggaaattgc       60

tcagaagacc tcttatgtat cctgaaaagg gctccattca agaagtcatg ggcctacctc      120

caagtggcaa agcatctaaa caaaaccaag ttgtcttgga acaaagatgg cattctccat      180

ggagtcagat atcaggatgg gaatctggtg atccaattcc ctggtttgta cttcatcatt      240

tgccaactgc agtttcttgt acaatgccca aataattctg tcgatctgaa gttggagctt      300

ctcatcaaca agcatatcaa aaaacaggcc ctggtgacag tgtgtgagtc tggaatgcaa      360

acgaaacacg tataccagaa tctctctcaa ttcttgctgg attacctgca ggtcaacacc      420

accatatcag tcaatgtgga tacattccag tacatagata caagcacctt tcctcttgag      480

aatgtgttgt ccatcttctt atacagtaat tcagac                                516


<210>  4414
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  4414
gcctgcccct gggccgtgtc cggggctcgc gcctcgcccg gctccgcggc cagcccgaga       60

ctccgcgagg gtcccgagct ttcgcccgac gatcccgccg gcctcttgga cctgcggcag      120

ggcatgtttg cgcagctggt ggcccaaaat gttctgctga tcgatgggcc cctgagctgg      180

tacagtgacc caggcctggc aggcgtgtcc ctgacggggg gcctgagcta caaagaggac      240

acgaaggagc tggtggtggc caaggctgga gtctactatg tcttctttca actagagctg      300

cggcgcgtgg tggccggcga gggctcaggc tccgtttcac ttgcgctgca cctgcagcca      360

ctgcgctctg ctgctggggc cgccgccctg gctttgaccg tggacctgcc acccgcctcc      420

tccgaggctc ggaactcggc cttcggtttc cagggccgct tgctgcacct gagtgccggc      480

cagcgcctgg gcgtccatct tcacactgag gccagggcac gccatgcctg gcagcttacc      540

cagggcgcca cagtcttggg actcttccgg gtgacccccg aaatcccagc cggactccct      600

tcaccgaggt cggaa                                                       615


<210>  4415
<211>  3813
<212>  DNA
<213>  Homo Sapiens

<400>  4415
gagcctcccg gctgcagcaa caaggagcaa caggtcactg tcagccacac ctacaagatc       60

gatgtgccca agtctgcctt ggttcaggtt gacgctgacc ctcagcccct cagtgacgat      120

ggggcttcgc tcttggccct gggggaggcc agggaggaac agaacatcat cttcaggcac      180

aacatccgcc ttcagacgcc acagaaggac tgcgagttgg caggcagtgt ccaggacctc      240

ctggcccggg tgaagaagct ggaggaagag atggtggaga tgaaggaaca gtgtagtgcc      300

cagcgctgct gccagggagt cactgatcta agccgccact gcagcggcca cgggaccttc      360

tccctggaga cctgcagctg ccactgcgaa gagggcaggg agggccccgc ctgcgagcgg      420

ctggcctgcc ccggggcgtg cagcggccac gggcgttgcg tggacgggcg ctgcctgtgc      480

catgagccct acgtgggtgc cgactgcggc tacccggcct gccctgagaa ctgcagcgga      540

cacggcgagt gcgtgcgcgg cgtgtgccag tgccacgaag acttcatgtc ggaggactgc      600

agcgagaagc gctgtcccgg cgactgcagc ggccacggct tctgtgacac gggcgagtgc      660

tactgcgagg agggcttcac aggcctggac tgtgcccagg tggtcacccc acagggcctg      720

cagctgctca agaacacgga ggattctctg ctggtgagct gggagccctc cagccaggtg      780

gatcactacc tcctcagcta ctaccccctg gggaaggagc tctctgggaa gcagatccaa      840

gtgcccaagg agcagcacag ctatgagatt cttggtttgc tgcctggaac caagtacata      900

gtcaccctgc gtaacgtcaa gaatgaagtt tctagcagcc cacagcatct acttgccacc      960

acagaccttg ctgtgcttgg cactgcctgg gtgacagatg agactgagaa ctcccttgac     1020

gtggagtggg aaaacccctc aactgaggtg gactactaca agctgcgata tggccccatg     1080

acaggacagg aggtagctga ggtcactgtg cccaagagta gtgaccccaa gagccgatat     1140

gacatcactg gtctgcaccc ggggactgag tataagatca cggtggtgcc catgagagga     1200

gagctggagg gcaagccgat cctcctgaat ggcaggacag aaattgacag tccaaccaat     1260

gttgtcactg atcgagtgac tgaagacaca gcaactgtct cctgggaccc agtgcaggct     1320

gtcatagaca agtatgtagt gcgctacact tctgctgatg gggacaccaa ggaaatggca     1380

gtgcacaagg atgagagcag cactgtcctg acgggcctga agccaggaga ggcatacaag     1440

gtctacgtgt gggctgaaag gggcaaccag gggagcaaga aagctgacac caatgccctc     1500

acagaaattg acagcccagc aaacctggtg actgaccggg tgactgagaa taccgccacc     1560

atctcctggg acccggtaca ggccaccatt gacaagtacg tggtgcgcta cacctctgct     1620

gacgaccaag agaccagaga ggttctggtg gggaaggagc agagcagcac tgtcctgaca     1680

ggcctgaggc caggtgtgga gtacacagtg catgtctggg cccagaaggg ggaccgagag     1740

agcaagaagg ctgacaccaa cgccccgaca gatattgaca gccccaaaaa cctggtgact     1800

gaccgggtga cagagaatat ggccacggtc tcctgggacc cggtgcaggc cgccattgac     1860

aagtacgtgg tgcgctacac ctctgctggt ggagagacca gggaggttcc ggtggggaag     1920

gagcagagca gcacagtcct gacaggcctg agaccgggta tggagtacat ggtgcacgtg     1980

tgggcccaga agggggacca ggagagcaag aaggccgaca ccaaggccca gacagacatt     2040

gacagccccc aaaacctggt gaccgaccgg gtgacagaga atatggccac tgtctcctgg     2100

gacccggtgc gggccaccat tgacaggtat gtggtgcgct acacctctgc caaggacgga     2160

gagaccaggg aggttccggt ggggaaggag cagagtagca ctgtcctgac gggcctgagg     2220

ccgggtgtgg agtacacggt gcacgtgtgg gcccagaagg gggcccagga gagcaagaag     2280

gctgacacca aggcccagac agacattgac agcccccaaa acctggtcac tgactgggtg     2340

acagagaata cagccactgt ctcctgggac ccggtgcagg ccaccattga caggtatgtg     2400

gtgcactaca cgtctgccaa cggagagacc agggaggttc cagtggggaa ggagcagagc     2460

agcactgtcc tgacgggcct gaggccgggc atggagtaca cggtgcacgt gtgggcccag     2520

aaggggaacc aggagagcaa gaaggctgac accaaggccc agacagaaat tgacggcccc     2580

aaaaacctag tgactgactg ggtgacggag aatatggcca ctgtctcctg ggacccggtt     2640

caggccacca ttgacaagta catggtgcgc tacacctctg ctgacggaga gaccagggag     2700

gttccggtgg ggaaggagca cagcagcact gtcctgacgg gcctgagacc aggcatggag     2760

tacatggtgc acgtgtgggc ccagaagggg gcccaggaga gcaagaaggc tgacaccaag     2820

gcccagacag aactcgaccc tcccagaaac cttcgtccat ctgctgtaac gcagtctggt     2880

ggcatattga cctggacgcc cccctctgct cagatccacg gctacattct gacttaccag     2940

ttcccagatg gcacagttaa ggagatgcag ctgggacggg aagaccagag gtttgcgttg     3000

caaggccttg agcaaggcgc cacctaccct gtctcccttg ttgcctttaa gggtggtcgc     3060

cggagcagaa atgtatccac caccctctcc acagttggtg cccgtttccc acacccttcg     3120

gactgcagtc aggttcagca gaacagcaat gccgccagtg gtctgtacac catctacctg     3180

catggcgatg ccagccggcc cctgcaggtg tactgtgaca tggaaacgga cggaggtggc     3240

tggattgtct tccagaggcg gaacactggg cagctggatt tcttcaagcg atggaggagc     3300

tatgtggaag gctttgggga ccccatgaag gagttctggc ttggacttga caagctacac     3360

aacctcacca ccggcactcc agcgcggtat gaggtgagag tggatttaca gactgccaat     3420

gaatctgcct atgctatata tgatttcttc caagtggcct ccagcaagga gcggtataag     3480

ctgacagttg ggaaatacag aggcacggca ggggatgctc ttacttacca caatggatgg     3540

aagtttacaa cttttgacag agacaacgat atcgcactca gcaactgtgc cctgacacat     3600

catggtggct ggtggtataa gaactgccac ttggccaacc ctaatggcag atatggggag     3660

accaagcaca gtgagggggt gaactgggag ccttggaaag gacatgaatt ctccattcct     3720

tacgtggagt tgaaaatccg ccctcatggc tacagcaggg agcctgtcct gggcagaaag     3780

aagcggacgc tgagaggaag gctgcgaacg ttc                                  3813


<210>  4416
<211>  3513
<212>  DNA
<213>  Homo Sapiens

<400>  4416
tgcatctgca acgaaggctg gtttggcaag aattgctcgg agccctactg cccgctgggt       60

tgctccagcc ggggggtgtg tgtggatggc cagtgcatct gtgacagcga gtacagcggg      120

gatgactgtt ccgaactccg gtgcccaaca gactgcagct cccgggggct ctgcgtggac      180

ggggagtgtg tctgtgaaga gccctacact ggcgaggact gcagggaact gaggtgccct      240

ggggactgtt cggggaaggg gagatgtgcc aacggtacct gtttatgcga ggagggctac      300

gttggtgagg actgcggcca gcggcagtgt ctgaatgcct gcagtgggcg aggacaatgt      360

gaggaggggc tctgcgtctg tgaagagggc taccagggcc ctgactgctc agcagttgcc      420

cctccagagg acttgcgagt ggctggtatc agcgacaggt ccattgagct ggaatgggac      480

gggccgatgg cagtgacgga atatgtgatc tcttaccagc cgacggccct ggggggcctc      540

cagctccagc agcgggtgcc tggagattgg agtggtgtca ccatcacgga gctggagcca      600

ggtctcacct acaacatcag cgtctacgct gtcattagca acatcctcag ccttcccatc      660

actgccaagg tggccaccca tctctccact cctcaagggc tacaatttaa gacgatcaca      720

gagaccaccg tggaggtgca gtgggagccc ttctcatttt ccttcgatgg gtgggaaatc      780

agcttcattc caaagaacaa tgaaggggga gtgattgctc aggtccccag cgatgttacg      840

tcctttaacc agacaggact aaagcctggg gaggaataca ttgtcaatgt ggtggctctg      900

aaagaacagg cccgcagccc ccctacctcg gccagcgtct ccacagtcat tgacggcccc      960

acgcagatcc tggttcgcga tgtctcggac actgtggctt ttgtggagtg gattccccct     1020

cgagccaaag tcgatttcat tcttttgaaa tatggcctgg tgggcgggga aggtgggagg     1080

accaccttcc ggctgcagcc tcccctgagc caatactcag tgcaggccct gcggcctggc     1140

tcccgatacg aggtgtcagt cagtgccgtc cgagggacca acgagagcga ttctgccacc     1200

actcagttca caacagagat cgatgccccc aagaacttgc gagttggttc tcgcacagca     1260

accagccttg acctcgagtg ggataacagt gaagccgaag ttcaggagta caaggttgtg     1320

tacagcaccc tggcgggtga gcaatatcat gaggtactgg tccccagggg cattggtcca     1380

accaccaggg ccaccctgac agatctggta cctggcactg agtatggagt tggaatatct     1440

gccgtcatga actcacagca aagcgtgcca gccaccatga atgccaggac tgaacttgac     1500

agtccccgag acctcatggt gacagcctcc tcagagacct ccatctccct catctggacc     1560

aaggccagtg gccccattga ccactaccga attaccttta ccccatcctc tgggattgcc     1620

tcagaagtca ccgtacccaa ggacaggacc tcatacacac taacagatct agagcctggg     1680

gcagagtaca tcatttccgt cactgctgag aggggtcggc agcagagctt ggagtccact     1740

gtggatgctt tcacaggctt ccgtcccatc tctcatctgc acttttctca tgtgacctcc     1800

tccagtgtga acatcacttg gagtgatcca tctcccccag cagacagact cattcttaac     1860

tacagcccca gggatgagga ggaagagatg atggaggtct ccctggatgc caccaagagg     1920

catgctgtcc tgatgggcct gcaaccagcc acagagtata ttgtgaacct tgtggctgtc     1980

catggcacag tgacctctga gcccattgtg ggctccatca ccacaggaat tgatccccca     2040

aaagacatca caattagcaa tgtgaccaag gactcagtga tggtctcctg gagccctcct     2100

gttgcatctt tcgattacta ccgagtatca tatcgaccca cccaagtggg acgactagac     2160

agctcagtgg tgcccaacac tgtgacagaa ttcaccatca ccagactgaa cccagctacc     2220

gaatacgaaa tcagcctcaa cagcgtgcgg ggcagggagg aaagcgagcg catctgtact     2280

cttgtgcaca cagccatgga caaccctgtg gatctgattg ctaccaatat cactccaaca     2340

gaagccctgc tgcagtggaa ggcaccagtg ggtgaggtgg agaactacgt cattgttctt     2400

acacactttg cagtcgctgg agagaccatc cttgttgacg gagtcagtga ggaatttcgg     2460

cttgttgacc tgcttcctag cacccactat actgccacca tgtatgccac caatggacct     2520

ctcaccagtg gcaccatcag caccaacttt tctactctcc tggaccctcc ggcaaacctg     2580

acagccagtg aagtcaccag acaaagtgcc ctgatctcct ggcagcctcc cagggcagag     2640

attgaaaatt atgtcttgac ctacaaatcc accgacggaa gccgcaagga gctgattgtg     2700

gatgcagaag acacctggat tcgactggag ggcctgttgg agaacacaga ctacacggtg     2760

ctcctgcagg cagcacagga caccacgtgg agcagcatca cctccaccgc tttcaccaca     2820

ggaggccggg tgttccctca tccccaagac tgtgcccagc atttgatgaa tggagacact     2880

ttgagtgggg tttaccccat cttcctcaat ggggagctga gccagaaatt acaagtgtac     2940

tgtgatatga ccaccgacgg gggcggctgg attgtattcc agaggcggca gaatggccaa     3000

actgattttt tccggaaatg ggctgattac cgtgttggct tcgggaacgt ggaggatgag     3060

ttctggctgg ggctggacaa tatacacagg atcacatccc agggccgcta tgagctgcgc     3120

gtggacatgc gggatggcca ggaggccgcc ttcgcctcct acgacaggtt ctctgtcgag     3180

gacagcagaa acctgtacaa actccgcata ggaagctaca acggcactgc gggggactcc     3240

ctcagctatc atcaaggacg ccctttctcc acagaggata gagacaatga tgttgcagtg     3300

actaactgtg ccatgtcgta caagggagca tggtggtata agaactgcca ccggaccaac     3360

ctcaatggga agtacgggga gtccaggcac agtcagggca tcaactggta ccattggaaa     3420

ggccatgagt tctccatccc ctttgtggaa atgaagatgc gcccctacaa ccaccgtctc     3480

atggcaggga gaaaacggca gtccttacag ttc                                  3513


<210>  4417
<211>  2382
<212>  DNA
<213>  Homo Sapiens

<400>  4417
cacctggggg aactgaccgt ggctgaggag acctccagct ctctgcgcct gtcctggacg       60

gtagcccagg gcccctttga ctccttcgtg gtccagtaca gggacacgga cgggcagccc      120

agggcagtgc ctgtggccgc agaccagcgc acagtcaccg tagaggacct ggagcctggc      180

aagaaataca agtttctgct ctacgggctc cttgggggaa agcgcctggg cccggtctct      240

gccctgggaa tgacagcccc agaagaggac acaccagccc cagagttagc cccagaggcc      300

cctgagcctc ctgaagagcc ccgcctagga gtgctgaccg tgaccgacac aaccccagac      360

tccatgcgcc tctcgtggag cgtggcccag ggcccctttg attccttcgt ggtccagtat      420

gaggacacga acgggcagcc ccaggccttg ctcgtggacg gcgaccagag caagatcctc      480

atctcaggcc tggagcccag caccccctac aggttcctcc tctatggcct ccatgaaggg      540

aagcgcctgg ggcccctctc agctgagggc accacagggc tggctcctgc tggtcagacc      600

tcagaggagt caaggccccg cctgtcccag ctgtctgtga ctgacgtgac caccagttca      660

ctgaggctca actgggaggc cccaccgggg gccttcgact ccttcctgct ccgctttggg      720

gttccatcac caagcactct ggagccgcat ccgcgtccac tgctgcagcg cgagctgatg      780

gtgccgggga cgcggcactc ggccgtgctc cgggacctgc gttccgggac tctgtacagc      840

ctgacactgt atgggctgcg aggaccccac aaggccgaca gcatccaggg aaccgcccgc      900

accctcagcc cagttctgga gagcccccgt gacctccaat tcagtgaaat cagggagacc      960

tcagccaagg tcaactggat gcccccacca tcccgggcgg acagcttcaa agtctcctac     1020

ctgctggcgg acggagggga gcctcagagt gtgcaggtgg atggccaggc ccggacccag     1080

aaactccagg ggctgatccc aggcgctcgc tatgaggtga ccgtggtctc ggtccgaggc     1140

tttgaggaga gtgagcctct cacaggcttc ctcaccacgg ttcctgacgg tcccacacag     1200

ttgcgtgcac tgaacttgac cgagggattc gccgtgctgc actggaagcc cccccagaat     1260

cctgtggaca cctatgacgt ccaggtcaca gcccctgggg ccccgcctct gcaggcggag     1320

accccaggca gcgcggtgga ctaccccctg catgaccttg tcctccacac caactacacc     1380

gccacagtgc gtggcctgcg gggccccaac ctcacttccc cagccagcat caccttcacc     1440

acagggctag aggcccctcg ggacttggag gccaaggaag tgaccccccg caccgccctg     1500

ctcacttgga ctgagccccc agtccggccc gcaggctacc tgctcagctt ccacacccct     1560

ggtggacaga accaggagat cctgctccca ggagggatca catctcacca gctccttggc     1620

ctctttccct ccacctccta caatgcacgg ctccaggcca tgtggggcca gagcctcctg     1680

ccgcccgtgt ccacctcttt caccacgggt gggctgcgga tccccttccc cagggactgc     1740

ggggaggaga tgcagaacgg agccggtgcc tccaggacca gcaccatctt cctcaacggc     1800

aaccgcgagc ggcccctgaa cgtgttttgc gacatggaga ctgatggggg cggctggctg     1860

gtgttccagc gccgcatgga tggacagaca gacttctgga gggactggga ggactatgcc     1920

catggttttg ggaacatctc tggagagttc tggctgggca atgaggccct gcacagcctg     1980

acacaggcag gtgactactc catgcgcgtg gacctgcggg ctggggacga ggctgtgttc     2040

gcccagtacg actccttcca cgtagactcg gctgcggagt actaccgcct ccacttggag     2100

ggctaccacg gcaccgcagg ggactccatg agctaccaca gcggcagtgt cttctctgcc     2160

cgtgatcggg accccaacag cttgctcatc tcctgcgctg tctcctaccg aggggcctgg     2220

tggtacagga actgccacta cgccaacctc aacgggctct acgggagcac agtggaccat     2280

cagggagtga gctggtacca ctggaagggc ttcgagttct cggtgccctt cacggaaatg     2340

aagctgagac caagaaactt tcgctcccca gcggggggag gc                        2382


<210>  4418
<211>  972
<212>  DNA
<213>  Homo Sapiens

<400>  4418
tcttctccca cctcctcggc atcctccttc tcctcctcgg cgccgttcct ggcttccgcc       60

gtgtccgccc agcccccgct gccggaccag tgccccgcgc tgtgcgagtg ctccgaggca      120

gcgcgcacag tcaagtgcgt taaccgcaat ctgaccgagg tgcccacgga cctgcccgcc      180

tacgtgcgca acctcttcct taccggcaac cagctggccg tgctccctgc cggcgccttc      240

gcccgccggc cgccgctggc ggagctggcc gcgctcaacc tcagcggcag ccgcctggac      300

gaggtgcgcg cgggcgcctt cgagcatctg cccagcctgc gccagctcga cctcagccac      360

aacccactgg ccgacctcag tcccttcgct ttctcgggca gcaatgccag cgtctcggcc      420

cccagtcccc ttgtggaact gatcctgaac cacatcgtgc cccctgaaga tgagcggcag      480

aaccggagct tcgagggcat ggtggtggcg gccctgctgg cgggccgtgc actgcagggg      540

ctccgccgct tggagctggc cagcaaccac ttcctttacc tgccgcggga tgtgctggcc      600

caactgccca gcctcaggca cctggactta agtaataatt cgctggtgag cctgacctac      660

gtgtccttcc gcaacctgac acatctagaa agcctccacc tggaggacaa tgccctcaag      720

gtccttcaca atggcaccct ggctgagttg caaggtctac cccacattag ggttttcctg      780

gacaacaatc cctgggtctg cgactgccac atggcagaca tggtgacctg gctcaaggaa      840

acagaggtag tgcagggcaa agaccggctc acctgtgcat atccggaaaa aatgaggaat      900

cgggtcctct tggaactcaa cagtgctgac ctggactgtg acccgattct tcccccatcc      960

ctgcaaacct ct                                                          972


<210>  4419
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  4419
tgtcctttcc aatgttactg cttcggtggg cccaagctac ttcttaggtg tgcgagtggg       60

gctgagttaa ggcagccgcc cagagacgtt ccgcctgacg cgcgtaacct gacgatagta      120

ggcgcaaatc tgaccgtact acgtgcggct gcctttgccg gtggggatgg tgatggagac      180

caagcagcgg gtgtgagatt accccttttg agtgcattac gtttaacgca caatcacatt      240

gaagtagtcg aggatggcgc gtttgacggc ctacccagtc tggccgctct agatttgtca      300

cataacccac tgagagcact gggcgggggt gcattcaggg gtttgcctgc gctgaggtca      360

ctacaactta atcacgctct tgtcaggggt ggacccgctt tacttgccgc cctagacgct      420

gccttggcac cgttagccga actacgtttg ttaggcctag cggggaatgc tttgtcaaga      480

ctaccccctg cggcccttag gttggcaagg ctggaacaat tagacgtccg tcttaacgct      540

cttgctggct tagacccgga tgaactaaga gccctagaaa gagacggtgg gctacctggc      600

ccgagattgc tattagcgga taatcctcta cgttgtggtt gtgccgcaag accgttgctg      660

gcatggctta gaaacgcaac tgagcgtgtc cccgattcca gaagacttag atgcgctgct      720

cccagagctc tgctagatag accactgtta gatctggatg gagctcgttt aagatgcgcg      780

gactcaggag cggacgcccg tggtgaagag gctgaagcgg ctggaccaga acttgaagca      840

tct                                                                    843


<210>  4420
<211>  2484
<212>  DNA
<213>  Homo Sapiens

<400>  4420
ttcttcccct tcatctcgag agggaaagaa ctcctttggg gaaagcctga ggagtctcgt       60

gtctctagcg tcttggagga aagcaagcgc ctggtggaca ccgccatgta cgccacgatg      120

cagagaaacc tcaagaaaag aggaatcctt tctgcagctc agcttctgtc tttttccaaa      180

cttcctgagc caacaagcgg agtgattgcc cgagcagcag agataatgga aacatcaata      240

caagcgatga aaagaaaagt caacctgaaa actcaacaat cacagcatcc aacggatgct      300

ttatcagaag atctgctgag catcattgca aacatgtctg gatgtctccc ttacatgctg      360

cccccaaaat gcccaaacac ttgcctggcg aacaaataca ggcccatcac aggagcttgc      420

aacaacagag accaccccag atggggcgcc tccaacacgg ccctggcacg atggctccct      480

ccagtctatg aggacggctt cagtcagccc cgaggctgga accccggctt cttgtacaac      540

gggttcccac tgcccccggt ccgggaggtg acaagacatg tcattcaagt ttcaaatgag      600

gttgtcacag atgatgaccg ctattctgac ctcctgatgg catggggaca atacatcgac      660

cacgacatcg cgttcacacc acagagcacc agcaaagctg ccttcggggg aggggctgac      720

tgccagatga cttgtgagaa ccaaaaccca tgttttccca tacaactccc ggaggaggcc      780

cggccggccg cgggcaccgc ctgtctgccc ttctaccgct cttcggccgc ctgcggcacc      840

ggggaccaag gcgcgctctt tgggaacctg tccacggcca acccgcggca gcagatgaac      900

gggttgacct cgttcctgga cgcgtccacc gtgtatggca gctccccggc cctagagagg      960

cagctgcgga actggaccag tgccgaaggg ctgctccgcg tccacgcgcg cctccgggac     1020

tccggccgcg cctacctgcc cttcgtgccg ccacgcgcgc ctgcggcctg tgcgcccgag     1080

cccggcatcc ccggagagac ccgcgggccc tgcttcctgg ccggagacgg ccgcgccagc     1140

gaggtcccct ccctgacggc actgcacacg ctgtggctgc gcgagcacaa ccgcctggcc     1200

gcggcgctca aggccctcaa tgcgcactgg agcgcggacg ccgtgtacca ggaggcgcgc     1260

aaggtcgtgg gcgctctgca ccagatcatc accctgaggg attacatccc caggatcctg     1320

ggacccgagg ccttccagca gtacgtgggt ccctatgaag gctatgactc caccgccaac     1380

cccactgtgt ccaacgtgtt ctccacagcc gccttccgct tcggccatgc cacgatccac     1440

ccgctggtga ggaggctgga cgccagcttc caggagcacc ccgacctgcc cgggctgtgg     1500

ctgcaccagg ctttcttcag cccatggaca ttactccgtg gaggtggttt ggacccacta     1560

atacgaggcc ttcttgcaag accagccaaa ctgcaggtgc aggatcagct gatgaacgag     1620

gagctgacgg aaaggctctt tgtgctgtcc aattccagca ccttggatct ggcgtccatc     1680

aacctgcaga ggggccggga ccacgggctg ccaggttaca atgagtggag ggagttctgc     1740

ggcctgcctc gcctggagac ccccgctgac ctgagcacag ccatcgccag caggagcgtg     1800

gccgacaaga tcctggactt gtacaagcat cctgacaaca tcgatgtctg gctgggaggc     1860

ttagctgaaa acttcctccc cagggctcgg acagggcccc tgtttgcctg tctcattggg     1920

aagcagatga aggctctgcg ggacggtgac tggttttggt gggagaacag ccacgtcttc     1980

acggatgcac agaggcgtga gctggagaag cactccctgt ctcgggtcat ctgtgacaac     2040

actggcctca ccagggtgcc catggatgcc ttccaagtcg gcaaattccc cgaagacttt     2100

gagtcttgtg acagcatcac tggcatgaac ctggaggcct ggagggaaac ctttcctcaa     2160

gacgacaagt gtggcttccc agagagcgtg gagaatgggg actttgtgca ctgtgaggag     2220

tctgggaggc gcgtgctggt gtattcctgc cggcacgggt atgagctcca aggccgggag     2280

cagctcactt gcacccagga aggatgggat ttccagcctc ccctctgcaa agatgtgaac     2340

gagtgtgcag acggtgccca ccccccctgc cacgcctctg cgaggtgcag aaacaccaaa     2400

ggcggcttcc agtgtctctg cgcggacccc tacgagttag gagacgatgg gagaacctgc     2460

gtagactccg ggaggctccc tcgg                                            2484


<210>  4421
<211>  1374
<212>  DNA
<213>  Homo Sapiens

<400>  4421
gcgtccagga gaggggcgcc tggcactgca aactgcgagc taaaacctca gcagtctgaa       60

ctgaactcct ttctatggac gatcaaaagg gatcctccct cttatttctt cggcacaatc      120

catgttccct acactagggt ttgggatttc atcccggata attctaaaga ggctttcttg      180

caaagttcta tcgtttattt tgagttggac cttactgatc catacaccat cagcgcattg      240

acctcatgcc agatgttacc acaaggtgaa aacctacagg atgtactgcc gcgtgacata      300

tattgcaggt taaagcgtca cttggaatat gtaaaactga tgatgccgct gtggatgacg      360

cctgaccaaa gaggtaaagg tttgtatgct gactacctat tcaacgctat cgcagggaac      420

tgggagagaa agaggcccgt atgggtgatg ctgatggtga actctcttac tgaagttgac      480

ataaaaagca gaggcgtacc cgtcctggat ctgttcctag cacaagaggc cgagaggcta      540

aggaaacaaa caggtgctgt tgagaaagtt gaggagcaat gtcatccttt gaacggtctt      600

aatttttctc aggtgatttt tgcattaaac caaacacttc tacaacagga atcattgagg      660

gccgggagtc tgcaaatacc atatactacg gaggacctta tcaaacatta caactgcggg      720

gacctttcca gcgttatact tagccacgac tctagtcagg taccaaattt cataaatgca      780

actctgcctc ctcaggaacg tatcactgca caggagatcg atagttactt acgtcgtgag      840

cttatttaca aacgtaacga aagaatcggt aaaagggtca aagcgttgct agaagagttc      900

ccggacaagg gtttcttctt cgccttcgga gcgggccact tcatggggaa taacacagtt      960

ttggacgttc tgcgtagaga aggctatgag gtcgaacacg cgcccgcggg aaggcccata     1020

cataagggta aatcaaagaa gacgtcaacg cgtcccaccc tgagtacaat ctttgcaccg     1080

aaagtcccaa cacttgaggt gcccgcgccg gaggccgtct ctagcggcca tagtacctta     1140

cctccattag tcagtcgtcc cgggtcagca gatacaccaa gtgaggcgga acagcgtttc     1200

cgtaaaaaga ggaggagatc acaaagacgt ccaagattaa gacaattttc tgacctttgg     1260

gtgcgtttag aggagtcaga catagttcca caactacagg ttcctgtttt agaccgtcat     1320

atatcaacgg aattacgtct gccaagacgt gggcattctc accactctca gatg           1374


<210>  4422
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  4422
gcaactaaat taactgagga aaagtatgaa ctgaaagagg ggcagaccct ggatgtgaaa       60

tgtgactaca cgctagagaa gtttgccagc agccagaaag cttggcagat aataagggac      120

ggagagatgc ccaagaccct ggcatgcaca gagaggcctt caaagaattc ccatccagtc      180

caagtgggga ggatcatact agaagactac catgatcatg gtttactgcg cgtccgaatg      240

gtcaaccttc aagtggaaga ttctggactg tatcagtgtg tgatctacca gcctcccaag      300

gagcctcaca tgctgttcga tcgcatccgc ttggtggtga ccaagggttt ttcagggacc      360

cctggctcca atgagaattc tacccagaat gtgtataaga ttcctcctac caccactaag      420

gccttgtgcc cactctatac cagccccaga actgtgaccc aagctccacc caagtcaact      480

gccgatgtct ccactcctga ctctgaaatc aaccttacaa atgtgacaga tatcatcagg      540

gttccggtgt tcaac                                                       555


<210>  4423
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  4423
cacaacacca cagtgttcca gggcgtggcg ggccagtccc tgcaggtgtc ttgcccctat       60

gactccatga agcactgggg gaggcgcaag gcctggtgcc gccagctggg agagaagggc      120

ccatgccagc gtgtggtcag cacgcacaac ttgtggctgc tgtccttcct gaggaggtgg      180

aatgggagca cagccatcac agacgatacc ctgggtggca ctctcaccat tacgctgcgg      240

aatctacaac cccatgatgc gggtctctac cagtgccaga gcctccatgg cagtgaggct      300

gacaccctca ggaaggtcct ggtggaggtg ctggcagacc ccctggatca ccgggatgct      360

ggagatctct ggttccccgg ggagtctgag agcttcgagg atgcccatgt ggagcacagc      420

atctccaggc catctcaagg ctcccatctg ccttcttgtc tctccaagga gcctcttgga      480

aggagaaatc cccttcccac ccacttccat ccttctcctc ctggcctgca tctttctcat      540

caagattcta gcagccagcg ccctctgggc tgcagcctgg catggacaga agccagggac      600

acatccaccc ag                                                          612


<210>  4424
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  4424
cagggcatag ttggcagcct ccctgaggtg ctgcaggcac ccgtgggaag ctccattctg       60

gtgcagtgcc actacaggct ccaggatgtc aaagctcaga aggtgtggtg ccggttcttg      120

ccggaggggt gccagcccct ggtgtcctca gctgtggatc gcagagctcc agcgggcagg      180

cgtacgtttc tcacagacct gggtgggggc ctgctgcagg tggaaatggt taccctgcag      240

gaagaggatg ctggcgagta tggctgcatg gtggatgggg ccagggggcc ccagattttg      300

cacagagtct ctctgaacat actgccccca gaggaagaag aagagaccca taagattggc      360

agtctggctg agaacgcatt ctcagaccct gcaggcagtg ccaacccttt ggaacccagc      420

caggatgaga agagcatccc c                                                441


<210>  4425
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  4425
ggcccctctg ctgacagtgt atacacaaaa gtgaggctcc ttgaagggga gactctgtct       60

gtgcagtgct cctataaggg ctacaaaaac cgcgtggagg gcaaggtttg gtgcaaaatc      120

aggaagaaga agtgtgagcc tggctttgcc cgagtctggg tgaaagggcc ccgctacttg      180

ctgcaggacg atgcccaggc caaggtggtc aacatcacca tggtggccct caagctccag      240

gactcaggcc gatactggtg catgcgcaat acctctggga tcctgtaccc cttgatgggc      300

ttccagctgg atgtgtctcc agctccccaa agtgagagga acattccttt cacacatctg      360

gacaacatcc tcaagagtgg aactgtcaca actggccaag cccctacctc aggccctgat      420

gcccctttta ccactggtgt gatggtgttc accccaggac tcatcacctt gcctaggctc      480

ttagcctcca ccagacctgc ctccaagaca ggctacagct tcactgctac cagcaccacc      540

agccagggac ccaggaggac catggggtcc cagacagtga ccgcgtctcc cagcaatgcc      600

agggactcct ctgctggccc agaatccatc tccactaagt ctggggacct cagcaccaga      660

tcgcccacca cagggctctg cctcaccagc agatctctcc tcaacagact accctccatg      720

ccctccatca ggcaccagga tgtttactcc                                       750


<210>  4426
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  4426
gaagaacttc acaaacaccc aggacagacc ctcctcctgc aatgccagta ctcacccaag       60

agagggccct atcagcccaa atcctggtgt cagcagacat ctccaagtcg gtgtacctta      120

cttgtcacca gctccaagcc ctggacagca gttcagaagt ctcattacac aatctgggac      180

aagcccaatg ctggcttctt caacatcacc atgattcagc tgacacagaa tgactcggga      240

ttctactggt gtggaatcta caacgcttcc gaaaacatca tcactgttct tagaaatatc      300

agcctggtgg tgtctccagc cccaaccacg tctcctatgt ggactcttcc ctggctccca      360

acaagcacag ttctgatcac ttctccagag gggacctctg gccatccctc catcaatggc      420

tctgagacca ggaaatcaag agcccctgcc                                       450


<210>  4427
<211>  2013
<212>  DNA
<213>  Homo Sapiens

<400>  4427
gtgtgcccgg agcgctgcga ctgccagcat ccccagcatc tcctgtgcac caacaggggg       60

ctccgcgtag tgcccaagac cagctcgctg ccgagccccc acgacgtgct cacctacagc      120

ctcggcggca acttcataac caacatcacg gccttcgact tccaccgtct ggggcagctc      180

agacggctgg acctgcagta caaccagatc cgctctctgc accccaagac cttcgagaag      240

ctctcgcggc tggaagagct gtacctgggg aacaacctct tgcaggcgct cgccccgggc      300

acgctggccc cgctgcgcaa gctgcgcatc ctctacgcca acgggaacga gatcagccgc      360

ctaagccgcg gctccttcga gggcctggag agtctagtca agctgcggct ggacgggaac      420

gccctggggg cgctgccgga cgcggtcttc gctcccttgg gcaacctgct ctacctacat      480

ctggagtcca accggatccg ctttctgggc aagaacgcct tcgcccagct aggcaagctg      540

cgcttcctca acctctctgc caacgagcta cagccctccc tgcgccacgc ggccaccttc      600

gcaccgctgc gctccctctc ctccctcatc ctctcggcca acagcctgca gcacctcggg      660

ccgcgcatct tccagcacct gccacgtctc ggcctgctct cgctcagggg caaccagctc      720

acgcacctcg cgcctgaggc cttttggggc ttggaggccc tgcgcgagct gcgcctggag      780

ggtaatcggc tgagccagct gccaactgcg ctgctggagc ctctgcacag cctggaggcg      840

ctggacctga gcggcaatga gctgtccgcc ctgcacccgg ccaccttcgg ccacctgggc      900

cggctgcgcg agctcagcct gcgcaacaac gcgctcagcg ccctatccgg ggacatcttc      960

gccgccagcc cagcccttta tcggctggat ctagacggca acggctggac ctgcgactgc     1020

cggctgcgag gcctgaagcg ctggatgggc gactggcact cgcagggccg gctcctcact     1080

gtcttcgtgc agtgtcgcca ccccccggcc ctgcgaggca aatacctgga ttacctggat     1140

gaccagcagc tgcaaaatgg atcctgcgcg gatccctcgc cctcagcttc cctgaccgct     1200

gaccgcaggc ggcagcccct acccacggcc gcaggggagg agatgacgcc acctgcaggt     1260

ctcgcggagg agctgccgcc gcagccgcag ctccagcagc aggggcgatt tctagctggg     1320

gtggcctggg atggggccgc cagggagctg gtaggcaacc gcagcgctct aaggctgagt     1380

cggcggggcc cgggcctcca gcagcccagc ccctccgtcg ctgccgccgc gggcccggct     1440

ccacagtccc tagacctgca caagaagccc cagcggggcc gtccgactcg ggcagatccc     1500

gccctcgcgg agcccacccc aacggcctct cctggctctg cgccatcgcc cgccggcgac     1560

ccctggcagc gcgcgacgaa gcatcgtctg ggcacggagc accaggagcg tgccgcccag     1620

tccgacggtg gggccgggct gccgccgctg gtgtccgacc catgcgactt caacaagttc     1680

attctgtgca acctgacggt ggaggcggtg ggcgcagaca gcgcctcggt gcgctgggcc     1740

gtgcgcgagc accgcagtcc ccggccgctg ggcggcgcgc gcttccgcct gctctttgac     1800

cgctttggcc agcagcccaa gttccaccgc ttcgtctacc tgcctgagag cagcgactcg     1860

gccacgctgc gcgagctgcg cggggacacc ccctacctgg tgtgcgtgga gggcgtgctt     1920

gggggccgtg tctgccctgt ggctccccgg gaccactgcg cggggctggt caccctaccg     1980

gaggccggga gccggggcgg cgtcgactac cag                                  2013


<210>  4428
<211>  1179
<212>  DNA
<213>  Homo Sapiens

<400>  4428
ggaatggggt gttcgtctcc accctgcgag tgccatcagg aggaggactt cagagtcacc       60

tgcaaggata ttcaacgcat ccccagctta ccgcccagta cgcagactct gaagcttatt      120

gagactcacc tgagaactat tccaagtcat gcattttcta atctgcccaa tatttccaga      180

atctacgtat ctatagatgt gactctgcag cagctggaat cacactcctt ctacaatttg      240

agtaaagtga ctcacataga aattcggaat accaggaact taacttacat agaccctgat      300

gccctcaaag agctccccct cctaaagttc cttggcattt tcaacactgg acttaaaatg      360

ttccctgacc tgaccaaagt ttattccact gatatattct ttatacttga aattacagac      420

aacccttaca tgacgtcaat ccctgtgaat gcttttcagg gactatgcaa tgaaaccttg      480

acactgaagc tgtacaacaa tggctttact tcagtccaag gatatgcttt caatgggaca      540

aagctggatg ctgtttacct aaacaagaat aaatacctga cagttattga caaagatgca      600

tttggaggag tatacagtgg accaagcttg ctggacgtgt ctcaaaccag tgtcactgcc      660

cttccatcca aaggcctgga gcacctgaag gaactgatag caagaaacac ctggactctt      720

aagaaacttc cactttcctt gagtttcctt cacctcacac gggctgacct ttcttaccca      780

agccactgct gtgcttttaa gaatcagaag aaaatcagag gaatccttga gtccttgatg      840

tgtaatgaga gcagtatgca gagcttgcgc cagagaaaat ctgtgaatgc cttgaatagc      900

cccctccacc aggaatatga agagaatctg ggtgacagca ttgttgggta caaggaaaag      960

tccaagttcc aggatactca taacaacgct cattattacg tcttctttga agaacaagag     1020

gatgagatca ttggttttgg ccaggagctc aaaaaccccc aggaagagac tctacaagct     1080

tttgacagcc attatgacta caccatatgt ggggacagtg aagacatggt gtgtaccccc     1140

aagtccgatg agttcaaccc gtgtgaagac ataatgggc                            1179


<210>  4429
<211>  1011
<212>  DNA
<213>  Homo Sapiens

<400>  4429
acccggccat gcttccccgg gtgccaatgc gaggtggaga ccttcggcct tttcgacagc       60

ttcagcctga ctcgggtgga ttgtagcggc ctgggccccc acatcatgcc ggtgcccatc      120

cctctggaca cagcccactt ggacctgtcc tccaaccggc tggagatggt gaatgagtcg      180

gtgttggcgg ggccgggcta cacgacgttg gctggcctgg atctcagcca caacctgctc      240

accagcatct cacccactgc cttctcccgc cttcgctacc tggagtcgct tgacctcagc      300

cacaatggcc tgacagccct gccagccgag agcttcacca gctcacccct gagcgacgtg      360

aaccttagcc acaaccagct ccgggaggtc tcagtgtctg ccttcacgac gcacagtcag      420

ggccgggcac tacacgtgga cctctcccac aacctcattc accgcctcgt gccccacccc      480

acgagggccg gcctgcctgc gcccaccatt cagagcctga acctggcctg gaaccggctc      540

catgccgtgc ccaacctccg agacttgccc ctgcgctacc tgagcctgga tgggaaccct      600

ctagctgtca ttggtccggg tgccttcgcg gggctgggag gccttacaca cctgtctctg      660

gccagcctgc agaggctccc tgagctggcg cccagtggct tccgtgagct accgggcctg      720

caggtcctgg acctgtcggg caaccccaag cttaactggg caggagctga ggtgttttca      780

ggcctgagct ccctgcagga gctggacctt tcgggcacca acctggtgcc cctgcctgag      840

gcgctgctcc tccacctccc ggcactgcag agcgtcagcg tgggccagga tgtgcggtgc      900

cggcgcctgg tgcgggaggg cacctacccc cggaggcctg gctccagccc caaggtggcc      960

ctgcactgcg tagacacccg ggattctgct gccaggggcc ccaccatctt g              1011


<210>  4430
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  4430
tacgacttca ctaactgtga ctttgagaag attaaagcag cctatctcag tactatttct       60

aaagacctga ttacatatat gagtgggacc aaaagtaccg agttcaacaa caccgtctct      120

tgtagcaatc ggccacattg ccttactgaa atccagagcc taaccttcaa tcccaccgcc      180

ggctgcgcgt cgctcgccaa agaaatgttc gccatgaaaa ctaaggctgc cttagctatc      240

tggtgcccag gctattcgga aactcagata aatgctactc aggcaatgaa gaagaggaga      300

aaaaggaaag tcacaaccaa taaatgtctg gaacaagtgt cacaattaca aggattgtgg      360

cgtcgcttca atcgaccttt actgaaacaa cag                                   393


<210>  4431
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  4431
tacaccacaa tggctgagca cttcctgacg ttgctggtag tgcctgccat caagaaagat       60

tatggttccc aggaagactt cactcaagtg tggaacacca ccatgaaagg gctcaagtgc      120

tgtggcttca ccaactatac ggattttgag gactcaccct acttcaaaga gaacagtgcc      180

tttcccccat tctgttgcaa tgacaacgtc accaacacag ccaatgaaac ctgcaccaag      240

caaaaggctc acgaccaaaa agtagagggt tgcttcaatc agcttttgta tgacatccga      300

actaat                                                                 306


<210>  4432
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  4432
ggcgtttgga catatgaaca ggaacttatg gttccagtac aatggtcaga tatggtcact       60

ttgaaagcca ggatgacaaa ttatggatta cctagatatc ggtggcttac tcatgcttgg      120

aatttttttc agagagagtt taagtgctgt ggagtagtat atttcactga ctggttggaa      180

atgacagaga tggactggcc cccagattcc tgctgtgtta gagaattccc aggatgttcc      240

aaacaggccc accaggaaga tctcagtgac ctttatcaag agggttgtgg gaagaaaatg      300

tattcctttt tgagaggaac caaacaactg caggtgctga gg                         342


<210>  4433
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  4433
tgcgcttgtt tagccctgaa ccaggagcaa cagggtcagc ttctggaggt tggttggaac       60

aatacggcaa gtgctcgaaa tgacatccag agaaatctaa actgctgtgg gttccgaagt      120

gttaacccaa atgacacctg tctggctagc tgtgttaaaa gtgaccactc gtgctcgcca      180

tgtgctccaa tcataggaga atatgctgga gaggttttga ga                         222


<210>  4434
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4434
accttccgga accagaccat tgacttcctg aacgacaaca ttcgaagagg aattgagaac       60

tactatgatg atctggactt caaaaacatc atggactttg ttcagaaaaa gttcaagtgc      120

tgtggcgggg aggactaccg agattggagc aagaatcagt accacgactg cagtgcccct      180

ggacccctgg cctgtggggt gccctacacc tgctgcatca ggaacacgac agaagttgtc      240

aacaccatgt gtggctacaa aactatcgac aaggagcgtt tcagtgtgca ggatgtcatc      300

tacgtgcggg gctgcaccaa cgccgtgatc atctggttca tggacaacta caccatcatg      360

gcg                                                                    363


<210>  4435
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4435
gtcttcaagg actggattcg agaccagctc aacctcttca tcaacaacaa cgtcaaggcc       60

taccgggacg acattgacct ccagaacctc attgactttg ctcaggaata ctggtcttgc      120

tgcggagccc gaggccccaa tgactggaac ctcaatatct acttcaactg cactgacttg      180

aaccccagcc gggagcgctg cggggtgccc ttctcctgct gcgtcaggga ccctgcggag      240

gatgtcctca acacccagtg tggctacgac gtccggctca aactggagct ggagcagcag      300

ggcttcatcc acaccaaagg ctgcgtgggc cagtttgaga agtggctgca ggacaac         357


<210>  4436
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4436
gccttcatct tcagggaaaa tctcacccga gaattcttca ccaaggagct caccaagcac       60

taccagggca ataacgacac agacgtcttc tctgccacct ggaactcggt catgatcaca      120

tttggttgct gcggggtcaa cgggcctgaa gactttaagt ttgcatctgt gtttcgactc      180

ctgaccctgg atagtgaaga ggtgccggag gcctgctgcc ggagggaacc ccaaagtcgg      240

gacggggtcc tgctgagccg ggaggagtgc ctcctgggaa ggagcctatt cctaaacaag      300

cagggctgtt acacggtgat cctcaacacc ttcgagacct acgtctactt ggccgga         357


<210>  4437
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4437
ggcaaggggg tagctatccg acatgttcag accatgtatg aagaggctta caatgattac       60

cttaaagaca ggggaaaagg caatgggaca ctcatcacct tccactcaac atttcagtgc      120

tgtggaaaag aaagctccga acaggtccaa cctacatgcc caaaggagct tctaggacac      180

aagaattgca tcgatgaaat tgagaccata atcagtgtta agctccagct c               231


<210>  4438
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  4438
tacagagcaa aggtggaaaa tgaggttgat cgcagcattc agaaagtgta taagacctac       60

aatggaacca accctgatgc tgctagccgg gctattgatt atgtacagag acagctgcat      120

tgttgtggaa ttcacaacta ctcagactgg gaaaatacag attggttcaa agaaaccaaa      180

aaccagagtg tccctcttag ctgctgcaga gagactgcca gcaattgtaa tggcagcctg      240

gcccaccctt ccgacctcta tgctgagggg tgtgaggctc tagttgtgaa gaagctacaa      300

gaaatcatga tgcatgtg                                                    318


<210>  4439
<211>  240
<212>  DNA
<213>  Homo Sapiens

<400>  4439
tgctcatgtc tggctattaa ccgaagcaaa cagacagatg tcatcaatgc ttcttggtgg       60

gtcatgagca acaagactcg ggatgaactg gaaagaagtt ttgattgttg tggcttattc      120

aacctcacaa ccctgtatca acaagattat gatttctgca ctgcaatctg caagagccag      180

agccccacat gccagatgtg tggagaaaag tttcttaagc attcagacga agccctgaaa      240


<210>  4440
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  4440
ttctcagaca aggctcgagg gaaagtgagt gagatcatca acaatgccat tgtgcactac       60

cgagatgact tggatctgca gaacctcatt gattttggcc agaaaaagtt tagctgctgt      120

ggagggattt cctacaagga ctggtctcag aacatgtatt tcaactgctc agaagacaac      180

cccagtcgag agcgctgctc tgtgccttac tcctgttgct tgcctactcc tgaccaggca      240

gtgatcaaca ctatgtgtgg ccaaggtatg caggcctttg actacttgga agctagcaaa      300

gtcatctaca ccaatggctg tattgacaag ttggtcaact ggatacacag caac            354


<210>  4441
<211>  285
<212>  DNA
<213>  Homo Sapiens

<400>  4441
tacacggaca agattgacag gtatgcccag caagacctga agaaaggctt gcacctgtac       60

ggcacgcagg gcaacgtggg cctcaccaac gcctggagca tcatccagac cgacttccgc      120

tgctgtggcg tctccaacta cactgactgg ttcgaggtgt acaacgccac gcgggtacct      180

gactcctgct gcttggagtt cagtgagagc tgtgggctgc acgcccccgg cacctggtgg      240

aaggcgccgt gctacgagac ggtgaaggtg tggcttcagg agaac                      285


<210>  4442
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4442
gttttcaaag actggatcaa agaccagctg tatttcttta taaacaacaa catcagagca       60

tatcgggatg acattgattt gcaaaacctc atagacttca cccaggaata ttggcagtgc      120

tgtggggctt ttggagctga tgattggaac ctaaatattt acttcaattg cacagattcc      180

aatgcaagtc gagagcgatg tggcgttcca ttctcctgct gcactaaaga tcccgcagaa      240

gatgtcatca acactcagtg tggctatgat gccaggcaaa aaccagaagt tgaccagcag      300

attgtaatct acacgaaagg ctgtgtgccc cagtttgaga agtggttgca ggacaat         357


<210>  4443
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  4443
cgtcatgaga tcaaggacac cttcctgagg acttacacgg acactatgca gacttacaat       60

ggcaatgatg agaggagccg ggcagtggac catgtgcagc gcagcctgag ctgctgtggt      120

gtgcagaact acaccaactg gagcaccagc ccctacttcc tggagcatgg catccccccc      180

agctgctgca tgaacgaaac tgattgtaat ccccaggatc tacacaatct gactgtggcc      240

gccaccaaag ttaaccagaa gggttgttat gatctggtaa ctagtttcat ggagactaac      300

atg                                                                    303


<210>  4444
<211>  288
<212>  DNA
<213>  Homo Sapiens

<400>  4444
aaatctaagt ctgatcgcat tgtgaatgaa actctctatg aaaacacaaa gcttttgagc       60

gccacagggg aaagtgaaaa acaattccag gaagccataa ttgtgtttca agaagagttt      120

aaatgctgcg gtttggtcaa tggagctgct gattggggaa ataattttca acactatcct      180

gaattatgtg cctgtctaga taagcagaga ccatgccaaa gctataatgg aaaacaagtt      240

tacaaagaga cctgtatttc tttcataaaa gacttcttgg caaaaaat                   288


<210>  4445
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4445
tacatggaca aggtgaacga gaacgccaag aaggacctga aggaaggcct gctgctgtac       60

cacaccgaga acaacgtggg gctgaagaac gcctggaaca tcatccaggc tgagatgcga      120

tgctgtggtg tcactgacta cacagactgg tacccagtgc tgggggagaa cacggttccc      180

gaccgctgct gcatggagaa ctcccagggc tgcgggcgca acgccaccac gcctttgtgg      240

agaacgggct gctatgaaaa ggtgaagatg tggttcgatg acaataagca c               291


<210>  4446
<211>  1167
<212>  DNA
<213>  Homo Sapiens

<400>  4446
gcaggtctga agctcatggg agccccggtg aagctgacag tgtctcaggg gcagccggtg       60

aagctcaact gcagtgtgga ggggatggag gagcctgaca tccagtgggt gaaggatggg      120

gctgtggtcc agaacttgga ccagttgtac atcccagtca gcgagcagca ctggatcggc      180

ttcctcagcc tgaagtcagt ggagcgctct gacgccggcc ggtactggtg ccaggtggag      240

gatgggggtg aaaccgagat ctcccagcca gtgtggctca cggtagaagg tgtgccattt      300

ttcacagtgg agccaaaaga tctggcagtg ccacccaatg cccctttcca actgtcttgt      360

gaggctgtgg gtccccctga acctgttacc attgtctggt ggagaggaac tacgaagatc      420

gggggacccg ctccctctcc atctgtttta aatgtaacag gggtgaccca gagcaccatg      480

ttttcctgtg aagctcacaa cctaaaaggc ctggcctctt ctcgcacagc cactgttcac      540

cttcaagcac tgcctgcagc ccccttcaac atcaccgtga caaagctttc cagcagcaac      600

gctagtgtgg cctggatgcc aggtgccgat ggccgagctc tgctacagtc ctgtacagtt      660

caggtgacac aggccccagg aggctgggaa gtcctggctg ttgtggtccc tgtgcccccc      720

tttacctgcc tgctccggga cctggtgcct gccaccaact acagcctcag ggtgcgctgt      780

gccaatgcct tggggccctc tccctatgct gactgggtgc cctttcagac caagggtcta      840

gccccagcca gcgctcccca aaacctccat gccatccgca cagattcagg cctcatcttg      900

gagtgggaag aagtgatccc cgaggcccct ttggaaggcc ccctgggacc ctacaaactg      960

tcctgggttc aagacaatgg aacccaggat gagctgacag tggaggggac cagggccaat     1020

ttgacaggct gggatcccca aaaggacctg atcgtacgtg tgtgcgtctc caatgcagtt     1080

ggctgtggac cctggagtca gccactggtg gtctcttctc atgaccgtgc aggccagcag     1140

ggccctcctc acagccgcac atcctgg                                         1167


<210>  4447
<211>  57
<212>  DNA
<213>  Homo Sapiens

<400>  4447
ctccgtcctg tccaggccca ggcccagagc gattgcagtt gctctacggt gagcccg          57


<210>  4448
<211>  1683
<212>  DNA
<213>  Homo Sapiens

<400>  4448
gacacctcag aagcaagatg gtgctctgaa tgtcacagca atgccacctg cacggaggat       60

gaggccgtta cgacgtgcac ctgtcaggag ggcttcaccg gcgatggcct gacctgcgtg      120

gacctggatg agtgcgccat tcctggagct cacaactgct ccgccaacag cagctgcgta      180

aacacgccag gctccttctc ctgcgtctgc cccgaaggct tccgcctgtc gcccggtctc      240

ggctgcacag acgtggatga gtgcgctgag cctgggctta gccactgcca cgccctggcc      300

acatgtgtca atgtggtggg cagctacttg tgcgtatgcc ccgcgggcta ccggggggat      360

ggatggcact gtgagtgctc cccgggctcc tgcgggccgg ggttggactg cgtgcccgag      420

ggcgacgcgc tcgtgtgcgc ggatccgtgt caggcgcacc gcaccctgga cgagtactgg      480

cgcagcaccg agtacgggga gggctacgcc tgcgacacgg acctgcgcgg ctggtaccgc      540

ccccatccgt ccagcgacga gggcatcgtg agccgcaagg cctgcgcgca ctggagcggc      600

cactgctgcc tgtgggatgc gtccgtccag gtgaaggcct gtgccggcgg ctactacgtc      660

tacaacctga cagcgccccc cgagtgtcac ctggcgtact gcacagaccc cagctccgtg      720

gaggggacgt gtgaggagtg cagtatagac gaggactgca aatcgaataa tggcagatgg      780

cactgccagt gcaaacagga cttcaacatc actgatatct ccctcctgga gcacaggctg      840

gaatgtgggg ccaatgacat gaaggtgtcg ctgggcaagt gccagctgaa gagtctgggc      900

ttcgacaagg tcttcatgta cctgagtgac agccggtgct cgggcttcaa tgacagagac      960

aaccgggact gggtgtctgt agtgacccca gcccgggatg gcccctgtgg gacagtgttg     1020

acgaggaatg aaacccatgc cacttacagc aacaccctct acctggcaga tgagatcatc     1080

atccgtgacc tcaacatcaa aatcaacttt gcatgctcct accccctgga catgaaagtc     1140

agcctgaaga ccgccctaca gccaatggtc agtgctctaa acatcagagt gggcgggacc     1200

ggcatgttca ccgtgcggat ggcgctcttc cagacccctt cctacacgca gccctaccaa     1260

ggctcctccg tgacactgtc cactgaggct tttctctacg tgggcaccat gttggatggg     1320

ggcgacctgt cccgatttgc actgctcatg accaactgct atgccacacc cagtagcaat     1380

gccacggacc ccctgaagta cttcatcatc caggacagat gcccacacac tagagactca     1440

actatccaag tggtggagaa tggggagtcc tcccagggcc gattttccgt ccagatgttc     1500

cggtttgctg gaaactatga cctagtctac ctgcactgtg aagtctatct ctgtgacacc     1560

atgaatgaaa agtgcaagcc tacctgctct gggaccagat tccgaagtgg gagtgtcata     1620

gatcaatccc gtgtcctgaa cttgggtccc atcacacgga aaggtgtcca ggccacagtc     1680

tca                                                                   1683


<210>  4449
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  4449
cagcagagtg ccaccgtggc caacccagtg cctggtgcca acccggacct gcttccccac       60

ttcctggtgg agcccgagga tgtgtacatc gtcaagaaca agccagtgct gcttgtgtgc      120

aaggccgtgc ccgccacgca gatcttcttc aagtgcaacg gggagtgggt gcgccaggtg      180

gaccacgtga tcgagcgcag cacagacggg agcagtgggc tgcccaccat ggaggtccgc      240

attaatgtct caaggcagca ggtcgagaag gtgttcgggc tggaggaata ctggtgccag      300

tgcgtggcat ggagctcctc gggcaccacc aagagtcaga aggcctacat ccgcatagcc      360

tatttgcgca agaacttcga gcaggagccg ctggccaagg aggtgtccct ggagcagggc      420

atcgtgctgc cctgccgtcc accggagggc atccctccag ccgaggtgga gtggctccgg      480

aacgaggacc tggtggaccc gtccctggac cccaatgtat acatcacgcg ggagcacagc      540

ctggtggtgc gacaggcccg ccttgctgac acggccaact acacctgcgt ggccaagaac      600

atcgtggcac gtcgccgcag cgcctccgct gctgtcatcg tctacgtgga cggcagctgg      660

agcccgtgga gcaagtggtc ggcctgtggg ctggactgca cccactggcg gagccgtgag      720

tgctctgacc cagcaccccg caacggaggg gaggagtgcc agggcactga cctggacacc      780

cgcaactgta ccagtgacct ctgtgtacac actgcttctg gccctgagga cgtggccctc      840

tat                                                                    843


<210>  4450
<211>  1053
<212>  DNA
<213>  Homo Sapiens

<400>  4450
gggacagatt caggctctga ggttttgcca gactcattcc ccagcgcacc tgcggagcca       60

cttccttatt tcttgcaaga acctcaagac gcttatatag tgaaaaataa gcccgttgaa      120

ttgaggtgca gagctttccc tgctactcaa atctatttta agtgcaacgg tgagtgggtc      180

agccaaaacg atcatgtgac gcaagaaggg ctggacgagg caactggact gcgtgtcagg      240

gaggtgcaaa ttgaagtgag caggcaacag gtggaggagc tttttgggct agaagattat      300

tggtgtcaat gtgtcgcttg gagtagtgca ggcacaacaa agtcccgtag agcgtatgtt      360

cgtattgcgt atttgagaaa aaattttgat caggagccgc tggggaagga ggttcccctg      420

gatcatgagg tgttactaca atgcagacct cccgagggag tgcccgtcgc agaggttgaa      480

tggctaaaga atgaggatgt catagacccc actcaggata ctaacttttt attgacgata      540

gaccataacc ttataattag acaggcaagg ctaagcgata cagctaacta cacctgtgtt      600

gctaagaata tagttgccaa gagaagatct actactgcta cagtaatagt atacgtaaat      660

gggggctggt cttcttgggc ggagtggtct ccgtgcagta acaggtgcgg gaggggctgg      720

cagaagcgta ctaggacatg caccaacccg gctccgctga acggaggagc cttttgtgag      780

gggcaggcat tccaaaaaac agcatgcacc acaatttgtc cggtagacgg cgcttggacg      840

gagtggagta aatggagcgc gtgctcaact gaatgcgctc actggcgtag tagagagtgt      900

atggcaccgc ctcctcaaaa tggtggtagg gactgtagtg gaactctgtt ggatagcaaa      960

aactgcactg acggtctttg catgcagaac aaaaagactc tatctgatcc aaatagtcac     1020

cttcttgagg cgtccgggga cgcggccttg tac                                  1053


<210>  4451
<211>  1077
<212>  DNA
<213>  Homo Sapiens

<400>  4451
caagatgatg acttttttca tgaactccca gaaacttttc cttctgatcc acctgagcct       60

ctgccacatt tccttattga gcctgaagaa gcttatattg tgaagaataa gcctgtgaac      120

ctgtactgta aagcaagccc tgccacccag atctatttca agtgtaatag cgaatgggtt      180

catcagaagg accacatagt agatgaaaga gtagatgaaa cttccggtct cattgtccgg      240

gaagtgagca ttgagatttc gcgccagcaa gtggaagaac tctttggacc tgaagattac      300

tggtgccagt gtgtggcctg gagctccgcg ggtaccacaa agagccggaa ggcgtatgtg      360

cgcattgcat atctacggaa gacatttgag caggaacccc taggaaagga agtgtctttg      420

gaacaggaag tcttactcca gtgtcgacca cctgaaggga tcccagtggc tgaggtggaa      480

tggttgaaaa atgaagacat aattgatccc gttgaagatc ggaattttta tattattatt      540

gatcacaacc tcatcataaa gcaggcccga ctctctgata ctgcaaatta cacctgtgtt      600

gccaaaaaca ttgttgccaa gaggaaaagt acaactgcca ctgtcatagt ctatgtcaac      660

ggtggctggt ccacctggac ggagtggtct gtgtgtaaca gccgctgtgg acgagggtat      720

cagaaacgta caaggacttg taccaacccg gcaccactca atgggggtgc cttctgtgaa      780

gggcagagtg tgcagaaaat agcctgtact acgttatgcc cagtggatgg caggtggacg      840

ccatggagca agtggtctac ttgtggaact gagtgcaccc actggcgcag gagggagtgc      900

acggcgccag cccccaagaa tggaggcaag gactgcgacg gcctcgtctt gcaatccaag      960

aactgcactg atgggctttg catgcagagt ttcatttatc ccatttcaac tgaacagaga     1020

acccagaatg aatatggatt ttcttctgct cctgattcag atgatgttgc tctctat        1077


<210>  4452
<211>  1041
<212>  DNA
<213>  Homo Sapiens

<400>  4452
gctaggggaa ctgacaacgg tgaggcgtta ccagaatcaa ttcctagtgc accggggacc       60

ttacctcact ttatcgaaga gcctgatgac gcttacatca taaaatcaaa tccgatagcg      120

ctaagatgca aggcacgtcc agcaatgcaa attttcttca aatgcaacgg cgaatgggtt      180

caccagaatg aacatgtaag tgaagaaact ttagatgaaa gctctggtct aaaggtgaga      240

gaagtcttca ttaacgtaac gaggcaacaa gtagaagact ttcatgggcc ggaggactac      300

tggtgtcaat gtgttgcctg gagtcatctt ggaacgtcca aatctagaaa ggcttcagtc      360

aggattgcct acctaagaaa gaacttcgaa caagacccgc aggggagaga agtcccgatt      420

gaaggtatga tagttcttca ctgtaggcca ccagagggcg tccctgcggc agaagtggaa      480

tggcttaaga atgaggagcc gatagatagc gagcaagatg aaaatataga tactcgtgcg      540

gatcacaatc ttattataag acaggcccgt cttagtgaca gtggcaacta tacgtgtatg      600

gccgctaaca tagttgcgaa gaggagaagc ctgtccgcca ctgtggtggt ctatgttaat      660

ggaggatggt cctcatggac cgaatggtcc gcgtgtaacg tcagatgtgg gcgtggctgg      720

cagaagagga gtagaacttg taccaacccc gcaccactta atgggggagc attttgtgag      780

ggtatgagcg tacagaagat aacttgcacc tctctatgcc cggtagacgg ctcttgggaa      840

gtttggtccg agtggagcgt ctgctccccg gagtgtgagc acttaaggat ccgtgagtgt      900

accgcgccgc cacctcgtaa cgggggcaaa ttctgtgaag ggcttagcca ggagtccgaa      960

aattgcaccg acgggctgtg catccttgat aagaagcctt tgcacgaaat aaaaccccaa     1020

tcaatagaaa atgctagtga t                                               1041


<210>  4453
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4453
acgtcctaca cccaccgtga ctacatggtg tccaacccat ccctgatcac caagcagatg       60

ctgaccttct acagcgcgga caccgaccag ggccaggagc tgacccgcct ctgggaccgc      120

gtcatgattg agcaagaatg ctgtggcaca tctggtccca tggactgggt gaacttcacg      180

tcagccttcc gggcggccac tccggaggtg gtgttcccct ggcccccact gtgctgtcgc      240

cggacgggaa acttcatccc cctcaacgag gagggctgcc gcctggggca catggactac      300

ctgttcacca aggctggagt acagtggcac aatctcagct cactgcagcg t               351


<210>  4454
<211>  366
<212>  DNA
<213>  Homo Sapiens

<400>  4454
acagcagcaa cacaacgaga ctttttcaca cccaacctct tcctgaagca gatgctagag       60

aggtaccaaa acaacagccc tccaaacaat gatgaccagt ggaaaaacaa tggagtcacc      120

aaaacctggg acaggctcat gctccaggac aattgctgtg gcgtaaatgg tccatcagac      180

tggcaaaaat acacatctgc cttccggact gagaataatg atgctgacta tccctggcct      240

cgtcaatgct gtgttatgaa caatcttaaa gaacctctca acctggaggc ttgtaaacta      300

ggcgtgcctg gtttttatca caatcagggc tgctatgaac tgatctctgg tccaatgaac      360

cgacac                                                                 366


<210>  4455
<211>  1656
<212>  DNA
<213>  Homo Sapiens

<400>  4455
tgcccatccg gctgccagtg cagccagcca cagacagtct tctgcactgc ccgccagggg       60

accacggtgc cccgagacgt gccacccgac acggtggggc tgtacgtctt tgagaacggc      120

atcaccatgc tcgacgcagg cagctttgcc ggcctgccgg gcctgcagct cctggacctg      180

tcacagaacc agatcgccag cctgcccagc ggggtcttcc agccactcgc caacctcagc      240

aacctggacc tgacggccaa caggctgcat gaaatcacca atgagacctt ccgtggcctg      300

cggcgcctcg agcgcctcta cctgggcaag aaccgcatcc gccacatcca gcctggtgcc      360

ttcgacacgc tcgaccgcct cctggagctc aagctgcagg acaacgagct gcgggcactg      420

cccccgctgc gcctgccccg cctgctgctg ctggacctca gccacaacag cctcctggcc      480

ctggagcccg gcatcctgga cactgccaac gtggaggcgc tgcggctggc tggtctgggg      540

ctgcagcagc tggacgaggg gctcttcagc cgcttgcgca acctccacga cctggatgtg      600

tccgacaacc agctggagcg agtgccacct gtgatccgag gcctccgggg cctgacgcgc      660

ctgcggctgg ccggcaacac ccgcattgcc cagctgcggc ccgaggacct ggccggcctg      720

gctgccctgc aggagctgga tgtgagcaac ctaagcctgc aggccctgcc tggcgacctc      780

tcgggcctct tcccccgcct gcggctgctg gcagctgccc gcaacccctt caactgcgtg      840

tgccccctga gctggtttgg cccctgggtg cgcgagagcc acgtcacact ggccagccct      900

gaggagacgc gctgccactt cccgcccaag aacgctggcc ggctgctcct ggagcttgac      960

tacgccgact ttggctgccc agccaccacc accacagcca cagtgcccac cacgaggccc     1020

gtggtgcggg agcccacagc cttgtcttct agcttggctc ctacctggct tagccccaca     1080

gcgccggcca ctgaggcccc cagcccgccc tccactgccc caccgactgt agggcctgtc     1140

ccccagcccc aggactgccc accgtccacc tgcctcaatg ggggcacatg ccacctgggg     1200

acacggcacc acctggcgtg cttgtgcccc gaaggcttca cgggcctgta ctgtgagagc     1260

cagatggggc aggggacacg gcccagccct acaccagtca cgccgaggcc accacggtcc     1320

ctgaccctgg gcatcgagcc ggtgagcccc acctccctgc gcgtggggct gcagcgctac     1380

ctccagggga gctccgtgca gctcaggagc ctccgtctca cctatcgcaa cctatcgggc     1440

cctgataagc ggctggtgac gctgcgactg cctgcctcgc tcgctgagta cacggtcacc     1500

cagctgcggc ccaacgccac ttactccgtc tgtgtcatgc ctttggggcc cgggcgggtg     1560

ccggagggcg aggaggcctg cggggaggcc catacacccc cagccgtcca ctccaaccac     1620

gccccagtca cccaggcccg cgagggcaac ctgccg                               1656


<210>  4456
<211>  2022
<212>  DNA
<213>  Homo Sapiens

<400>  4456
tttaaaatcg agaccacccc agaatctaga tatcttgctc agattggtga ctccgtctca       60

ttgacttgca gcaccacagg ctgtgagtcc ccatttttct cttggagaac ccagatagat      120

agtccactga atgggaaggt gacgaatgag gggaccacat ctacgctgac aatgaatcct      180

gttagttttg ggaacgaaca ctcttacctg tgcacagcaa cttgtgaatc taggaaattg      240

gaaaaaggaa tccaggtgga gatctactct tttcctaagg atccagagat tcatttgagt      300

ggccctctgg aggctgggaa gccgatcaca gtcaagtgtt cagttgctga tgtataccca      360

tttgacaggc tggagataga cttactgaaa ggagatcatc tcatgaagag tcaggaattt      420

ctggaggatg cagacaggaa gtccctggaa accaagagtt tggaagtaac ctttactcct      480

gtcattgagg atattggaaa agttcttgtt tgccgagcta aattacacat tgatgaaatg      540

gattctgtgc ccacagtaag gcaggctgta aaagaattgc aagtctacat atcacccaag      600

aatacagtta tttctgtgaa tccatccaca aagctgcaag aaggtggctc tgtgaccatg      660

acctgttcca gcgagggtct accagctcca gagattttct ggagtaagaa attagataat      720

gggaatctac agcacctttc tggaaatgca actctcacct taattgctat gaggatggaa      780

gattctggaa tttatgtgtg tgaaggagtt aatttgattg ggaaaaacag aaaagaggtg      840

gaattaattg ttcaagagaa accatttact gttgagatct cccctggacc ccggattgct      900

gctcagattg gagactcagt catgttgaca tgtagtgtca tgggctgtga atccccatct      960

ttctcctgga gaacccagat agacagccct ctgagcggga aggtgaggag tgaggggacc     1020

aattccacgc tgaccctgag ccctgtgagt tttgagaacg aacactctta tctgtgcaca     1080

gtgacttgtg gacataagaa actggaaaag ggaatccagg tggagctcta ctcattccct     1140

agagatccag aaatcgagat gagtggtggc ctcgtgaatg ggagctctgt cactgtaagc     1200

tgcaaggttc ctagcgtgta cccccttgac cggctggaga ttgaattact taagggggag     1260

actattctgg agaatataga gtttttggag gatacggata tgaaatctct agagaacaaa     1320

agtttggaaa tgaccttcat ccctaccatt gaagatactg gaaaagctct tgtttgtcag     1380

gctaagttac atattgatga catggaattc gaacccaaac aaaggcagag tacgcaaaca     1440

ctttatgtca atgttgcccc cagagataca accgtcttgg tcagcccttc ctccatcctg     1500

gaggaaggca gttctgtgaa tatgacatgc ttgagccagg gctttcctgc tccgaaaatc     1560

ctgtggagca ggcagctccc taacggggag ctacagcctc tttctgagaa tgcaactctc     1620

accttaattt ctacaaaaat ggaagattct ggggtttatt tatgtgaagg aattaaccag     1680

gctggaagaa gcagaaagga agtggaatta attatccaag ttactccaaa agacataaaa     1740

cttacagctt ttccttctga gagtgtcaaa gaaggagaca ctgtcatcat ctcttgtaca     1800

tgtggaaatg ttccagaaac atggataatc ctgaagaaaa aagcggagac aggagacaca     1860

gtactaaaat ctatagatgg cgcctatacc atccgaaagg cccagttgaa ggatgcggga     1920

gtatatgaat gtgaatctaa aaacaaagtt ggctcacaat taagaagttt aacacttgat     1980

gttcaaggaa gagaaaacaa caaagactat ttttctcctg ag                        2022


<210>  4457
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4457
gcacccatgg cagaaggagg agggcagaat catcacgaag tggtgaagtt catggatgtc       60

tatcagcgca gctactgcca tccaatcgag accctggtgg acatcttcca ggagtaccct      120

gatgagatcg agtacatctt caagccatcc tgtgtgcccc tgatgcgatg cgggggctgc      180

tgcaatgacg agggcctgga gtgtgtgccc actgaggagt ccaacatcac catgcagatt      240

atgcggatca aacctcacca aggccagcac ataggagaga tgagcttcct acagcacaac      300

aaatgtgaat gcagaccaaa gaaagataga gcaagacaag aaaaatgtga caagccgagg      360

cgg                                                                    363


<210>  4458
<211>  558
<212>  DNA
<213>  Homo Sapiens

<400>  4458
cctgtctccc agcctgatgc ccctggccac cagaggaaag tggtgtcatg gatagatgtg       60

tatactcgcg ctacctgcca gccccgggag gtggtggtgc ccttgactgt ggagctcatg      120

ggcaccgtgg ccaaacagct ggtgcccagc tgcgtgactg tgcagcgctg tggtggctgc      180

tgccctgacg atggcctgga gtgtgtgccc actgggcagc accaagtccg gatgcagatc      240

ctcatgatcc ggtacccgag cagtcagctg ggggagatgt ccctggaaga acacagccag      300

tgtgaatgca gacctaaaaa aaaggacagt gctgtgaagc cagacagggc tgccactccc      360

caccaccgtc cccagccccg ttctgttccg ggctgggact ctgcccccgg agcaccctcc      420

ccagctgaca tcacccatcc cactccagcc ccaggcccct ctgcccacgc tgcacccagc      480

accaccagcg ccctgacccc cggacctgcc gctgccgctg ccgacgccgc agcttcctcc      540

gttgccaagg gcggggct                                                    558


<210>  4459
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  4459
gcacattata atacagagat cttgaaaagt attgataatg agtggagaaa gactcaatgc       60

atgccacggg aggtgtgtat agatgtgggg aaggagtttg gagtcgcgac aaacaccttc      120

tttaaacctc catgtgtgtc cgtctacaga tgtgggggtt gctgcaatag tgaggggctg      180

cagtgcatga acaccagcac gagctacctc agcaagacgt tatttgaaat tacagtgcct      240

ctctctcaag gccccaaacc agtaacaatc agttttgcca atcacacttc ctgccgatgc      300

atgtctaaac tggatgttta cagacaagtt cattccatta ttagacgt                   348


<210>  4460
<211>  2226
<212>  DNA
<213>  Homo Sapiens

<400>  4460
gggagaaaag ccaaatgtga accctcccaa ttccagtgca caaatggtcg ctgtattacg       60

ctgttgtgga aatgtgatgg ggatgaagac tgtgttgacg gcagtgatga aaagaactgt      120

gtaaagaaga cgtgtgctga atctgacttc gtgtgcaaca atggccagtg tgttcccagc      180

cgatggaagt gtgatggaga tcctgactgc gaagatggtt cagatgaaag cccagaacag      240

tgccatatga gaacatgccg catacatgaa atcagctgtg gcgcccattc tactcagtgt      300

atcccagtgt cctggagatg tgatggtgaa aatgattgtg acagtggaga agatgaagaa      360

aactgtggca atataacatg tagtcccgac gagttcacct gctccagtgg ccgctgcatc      420

tccaggaact ttgtatgcaa tggccaggat gactgcagcg atggcagtga tgagctggac      480

tgtgccccgc caacctgtgg cgcccatgag ttccagtgca gcacctcctc ctgcatcccc      540

atcagctggg tatgcgacga tgatgcagac tgctccgacc aatctgatga gtccctggag      600

cagtgtggcc gtcagccagt catacacacc aagtgtccag ccagcgaaat ccagtgcggc      660

tctggcgagt gcatccataa gaagtggcga tgtgatgggg accctgactg caaggatggc      720

agtgatgagg tcaactgtcc ctctcgaact tgccgacctg accaatttga atgtgaggat      780

ggcagctgca tccatggcag caggcagtgt aatggtatcc gagactgtgt cgatggttct      840

gatgaagtca actgcaaaaa tgtcaatcag tgcttgggcc ctggaaaatt caagtgcaga      900

agtggagaat gcatagatat cagcaaagta tgtaaccagg agcaggactg cagggactgg      960

agtgatgagc ccctgaaaga gtgtcatata aacgaatgct tggtaaataa tggtggatgt     1020

tctcatatct gcaaagacct agttataggc tacgagtgtg actgtgcagc tgggtttgaa     1080

ctgatagata ggaaaacctg tggagatatt gatgaatgcc aaaatccagg aatctgcagt     1140

caaatttgta tcaacttaaa aggcggttac aagtgtgaat gtagtcgtgg ctatcaaatg     1200

gatcttgcta ctggcgtgtg caaggcagta ggcaaagagc caagtctgat cttcactaat     1260

cgaagagaca tcaggaagat tggcttagag aggaaagaat atatccaact agttgaacag     1320

ctaagaaaca ctgtggctct cgatgctgac attgctgccc agaaactatt ctgggccgat     1380

ctaagccaaa aggctatctt cagtgcctca attgatgaca aggttggtag acatgttaaa     1440

atgatcgaca atgtctataa tcctgcagcc attgctgttg attgggtgta caagaccatc     1500

tactggactg atgcggcttc taagactatt tcagtagcta ccctagatgg aaccaagagg     1560

aagttcctgt ttaactctga cttgcgagag cctgcctcca tagctgtgga cccactgtct     1620

ggctttgttt actggtcaga ctggggtgaa ccagctaaaa tagaaaaagc aggaatgaat     1680

ggattcgata gacgtccact ggtgacagcg gatatccagt ggcctaacgg aattacactt     1740

gaccttataa aaagtcgcct ctattggctt gattctaagt tgcacatgtt atccagcgtg     1800

gacttgaatg gccaagatcg taggatagta ctaaagtctc tggagttcct agctcatcct     1860

cttgcactaa caatatttga ggatcgtgtc tactggatag atggggaaaa tgaagcagtc     1920

tatggtgcca ataaattcac tggatcagag ctagccactc tagtcaacaa cctgaatgat     1980

gcccaagaca tcattgtcta tcatgaactt gtacagccat caggtaaaaa ttggtgtgaa     2040

gaagacatgg agaatggagg atgtgaatac ctatgcctgc cagcaccaca gattaatgat     2100

cactctccaa aatatacctg ttcctgtccc agtgggtaca atgtagagga aaatggccga     2160

gactgtcaaa ggatcaatgt gaccacagca gtatcagagg tcagtgttcc cccaaaaggg     2220

acttct                                                                2226


<210>  4461
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  4461
gtgcaagtga ccatcccaga cggtttcgtg aacgtgactg ttggatctaa tgtcactctc       60

atctgcatct acaccaccac tgtggcctcc cgagaacagc tttccatcca gtggtctttc      120

ttccataaga aggagatgga gccaatttct atttactttt ctcaaggtgg acaagctgta      180

gccatcgggc aatttaaaga tcgaattaca gggtccaacg atccaggtaa tgcatctatc      240

actatctcgc atatgcagcc agcagacagt ggaatttaca tctgcgatgt taacaacccc      300

ccagactttc tcggccaaaa ccaaggcatc ctcaacgtca gtgtgttagt gaaaccttct      360

aagccccttt gtagcgttca aggaagacca gaaactggcc acactatttc cctttcctgt      420

ctctctgcgc ttggaacacc ttcccctgtg tactactggc ataaacttga gggaagagac      480

atcgtgccag tgaaagaaaa cttcaaccca accaccggga ttttggtcat tggaaatctg      540

acaaattttg aacaaggtta ttaccagtgt actgccatca acagacttgg caatagttcc      600

tgcgaaatcg atctcacttc ttcacatcca gaa                                   633


<210>  4462
<211>  1149
<212>  DNA
<213>  Homo Sapiens

<400>  4462
gttgtcattg gagaagttca tgagaatgtt actctgcact gtggcaacat ctcgggactg       60

aggggccagg tgacctggta ccggaacaac tcggagcctg tcttccttct ctcgtccaac      120

tctagcctcc ggccagctga gcctcgcttc tctctagtgg atgccacctc cctgcacatt      180

gaatcgctga gcctgggaga tgagggaatc tacacctgcc aggagatcct gaatgtgact      240

cagtggttcc aagtgtggct gcaggtggcc agcggcccct atcagattga ggtccacatc      300

gtggccaccg gcacactccc caacggcacc ctctatgcag ccaggggctc ccaggtggac      360

ttcagctgca acagcagctc caggccacca cccgtggttg aatggtggtt ccaggccctg      420

aattccagca gcgagtcctt tggccacaac ctgacagtca actttttctc actgttactg      480

atatcgccaa acctccaagg gaactacacc tgtttagcct tgaatcagct cagcaagaga      540

catcgaaagg tgaccaccga gctcctggtc tactatcccc ctccatcagc tccccagtgc      600

tgggcacaga tggcatcagg atcgttcatg ttgcagctta cctgtcgctg ggatggggga      660

taccctgacc ctgacttcct gtggatagaa gagccaggag gtgtaatcgt ggggaagtca      720

aagctggggg tggaaatgct gagcgagtcc cagctgtcgg atggcaagaa gttcaagtgt      780

gttacaagcc acatagttgg gccagagtcg ggcgccagct gcatggtgca gatcaggggt      840

ccctcccttc tctctgagcc catgaagact tgcttcactg ggggcaatgt gacgcttaca      900

tgccaggtgt ctggggccta cccccctgcc aagatcctgt ggctgaggaa ccttacccag      960

cccgaggtga tcatccagcc tagcagccgc catctcatta cccaggatgg ccagaactcc     1020

accctcacta tccacaactg ctcccaggac ctggatgagg gctactacat ctgccgagct     1080

gacagccctg taggggtgag ggagatggaa atctggctga gtgtgaaaga acctttaaat     1140

atcgggggg                                                             1149


<210>  4463
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  4463
gtggaggtga aggtacccac agagccgctg agcacgcccc tggggaagac agccgagctg       60

acctgcacct acagcacgtc ggtgggagac agcttcgccc tggagtggag ctttgtgcag      120

cctgggaaac ccatctctga gtcccatcca atcctgtact tcaccaatgg ccatctgtat      180

ccaactggtt ctaagtcaaa gcgggtcagc ctgcttcaga acccccccac agtgggggtg      240

gccacactga aactgactga cgtccacccc tcagatactg gaacctacct ctgccaagtc      300

aacaacccac cagatttcta caccaatggg ttggggctaa tcaaccttac tgtgctggtt      360

ccccccagta atcccttatg cagtcagagt ggacaaacct ctgtgggagg ctctactgca      420

ctgagatgca gctcttccga gggggctcct aagccagtgt acaactgggt gcgtcttgga      480

acttttccta caccttctcc tggcagcatg gttcaagatg aggtgtctgg ccagctcatt      540

ctcaccaacc tctccctgac ctcctcgggc acctaccgct gtgtggccac caaccagatg      600

ggcagtgcat cctgtgagct gaccctctct gtgaccgaac cctcccaagg ccgagtggcc      660


<210>  4464
<211>  792
<212>  DNA
<213>  Homo Sapiens

<400>  4464
cgtcccatcc tggaagtgcc agagagtgta acaggacctt ggaaagggga tgtgaatctt       60

ccctgcacct atgaccccct gcaaggctac acccaagtct tggtgaagtg gctggtacaa      120

cgtggctcag accctgtcac catctttcta cgtgactctt ctggagacca tatccagcag      180

gcaaagtacc agggccgcct gcatgtgagc cacaaggttc caggagatgt atccctccaa      240

ttgagcaccc tggagatgga tgaccggagc cactacacgt gtgaagtcac ctggcagact      300

cctgatggca accaagtcgt gagagataag attactgagc tccgtgtcca gaaactctct      360

gtctccaagc ccacagtgac aactggcagc ggttatggct tcacggtgcc ccagggaatg      420

aggattagcc ttcaatgcca ggctcggggt tctcctccca tcagttatat ttggtataag      480

caacagacta ataaccagga acccatcaaa gtagcaaccc taagtacctt actcttcaag      540

cctgcggtga tagccgactc aggctcctat ttctgcactg ccaagggcca ggttggctct      600

gagcagcaca gcgacattgt gaagtttgtg gtcaaagact cctcaaagct actcaagacc      660

aagactgagg cacctacaac catgacatac cccttgaaag caacatctac agtgaagcag      720

tcctgggact ggaccactga catggatggc taccttggag agaccagtgc tgggccagga      780

aagagcctgc ct                                                          792


<210>  4465
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  4465
gtgcggatca acggggatgg acaggaggtc ctgtacctgg cagaaggtga taatgtgagg       60

ctgggctgcc cctacgtcct ggaccctgag gactatggtc ccaatgggct ggacatcgag      120

tggatgcagg tcaactcaga ccccgcccac caccgagaga acgtgttcct tagttaccag      180

gacaagagga tcaaccatgg cagccttccc catctgcagc agagggtccg ctttgcagcc      240

tcagacccaa gccagtacga tgcctccatc aacctcatga acctgcaggt atctgataca      300

gccacttatg agtgccgggt gaagaagacc accatggcca cccggaaggt cattgtcact      360

gtccaagcac gacctgcagt gcccatgtgc tggacagagg gccacatgac atatggcaac      420

gatgtggtgc tgaagtgcta tgccagtggg ggctcccagc ccctctccta caagtgggcc      480

aagatcagtg ggcaccatta cccctatcga gctgggtctt acacctccca gcacagctac      540

cactcagagc tgtcctacca ggagtccttc cacagctcca taaaccaagg cctgaacaat      600

ggggacctgg tgttgaagga tatctccaga gcagatgatg ggctgtatca gtgcacagtg      660

gccaacaacg tgggctacag tgtttgtgtg gtggaggtga aggtctcaga ctcccggcgt      720

ataggc                                                                 726


<210>  4466
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4466
tacgaagatg agaaaaagaa tgagaaaccg cccaagccct ccctccacgc ctggcccagc       60

tcggtggttg aagccgagag caatgtgacc ctgaagtgtc aggctcattc ccagaatgtg      120

acatttgtgc tgcgcaaggt gaacgactct gggtacaagc aggaacagag ctcggcagaa      180

aacgaagctg aattcccctt cacggacctg aagcctaagg atgctgggag gtacttttgt      240

gcctacaaga caacagcctc ccatgagtgg tcagaaagca gtgaacactt gcagctggtg      300

gtcacagata aacacgatga acttgaagct ccctcaatga aaacagacac cagaacc         357


<210>  4467
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  4467
tcttctcaag caaaatttac cgagtttccg cggaacgtga cggcgaccga ggggcagaat       60

gtggagatgt cctgcgcctt ccagagcggc tccgcctcgg tgtatctgga gatccaatgg      120

tggttcctgc gggggccgga ggacctggat cccggggccg agggggccgg cgcgcaggtg      180

aagctcttgc ccgacagaga cccggacagc gacgggacca agatcagcac agtgaaagtc      240

caaggcaatg acatctccca caagcttcag atttccaaag tgaggaaaaa ggatgaaggc      300

ttatatgagt gcagggtgac tgatgccaac tacggggagc ttcaggaaca caaggcccaa      360

gcctatctga aagtcaatgc aaacagccat gcccgcagaa tgcaggcctt cgaagcctcg      420

cccatgtggc tgcaggatat gaagccccgc aagaacgtct ccgcagccat ccccagcagc      480

atccatggct ctgccaacca acgaacgcac tccacctcca gccctcaagt ggtagccaaa      540

atccccaaac aaagtccaca atcaggtatg gaaacccatt tcgagccttt tattttacca      600

ctcacaaacg ctccacagaa aggtcagtcg tatagagtag acagatttat gaatggtgat      660

ttt                                                                    663


<210>  4468
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4468
gcttttaccg aggttccaaa ggacgtgacc gttagagagg gtgatgatat agagatgcct       60

tgcgctttcc gtgcctccgg tgcgactagc tactcactgg agatccagtg gtggtatcta      120

aaagagcctc cgcgtgagct actacatgag ttagcgttat ctgtgccggg cgctcgttcc      180

aaggtgacaa acaaagacgc aacaaaaatt agcactgtcc gtgtgcaggg caacgacatc      240

tctcacaggt taaggctttc tgcggtgcgt ttacaagatg agggagtata tgaatgccgt      300

gtctctgatt atagcgatga tgacactcaa gaacacaaag ctcaagcaat gttgagggtc      360

ctttccaggt ttgctccccc gaacatgcaa gcagcagaag cggtaagcca tatacaatca      420

tcaggccccc gtcgtcacgg gcctgcctct gccgctaatg caaataacgc cggagcggct      480

tcacgtacaa cgagtgagcc tggaagggga gataaaagtc caccaccagg gagtcctcct      540

gcggcaatcg atcccgctgt tcccgaggcc gcagccgcct ctgcggcaca taccccgacg      600

acaacagtgg cagccgctgc agcggcatct agcgcgtctc cccctagcgg gcaagcagta      660

cttcttcgtc agagacacgg gtccggaacc gggagaagtt acact                      705


<210>  4469
<211>  540
<212>  DNA
<213>  Homo Sapiens

<400>  4469
acgcggcccg ccggccacgc gccctgggac aaccacgtct ccggccacgc cctgttcaca       60

gagacacccc atgacatgac agcacggacg ggcgaggacg tggagatggc ctgctccttc      120

cgcggcagcg gctccccctc ctactcgctg gagatccagt ggtggtatgt acggagccac      180

cgggactgga ccgacaagca ggcgtgggcc tcgaaccagc taaaagcatc tcagcaggaa      240

gacgcaggga aggaggcaac caaaataagt gtggtcaagg tggtgggcag caacatctcc      300

cacaagctgc gcctgtcccg ggtgaagccc acggacgaag gttcctacga gtgccgcgtc      360

atcgacttca gcgacggcaa ggcccggcac cacaaggtca aggcctacct gcgggtgcag      420

ccaggggaga actccgtcct gcatctgccc gaagcccctc ccgccgcgcc cgccccgccg      480

ccccccaagc caggcaagga gctgaggaag cgctcggtgg accaggaggc ctgcagcctc      540


<210>  4470
<211>  471
<212>  DNA
<213>  Homo Sapiens

<400>  4470
ctcaatgtca ctgtgtcccc ggggcccgtg gttgactacc tggaggggga gaatgccact       60

ctcctctgcc acgtctccca gaaaaggcgg aaggacagct tgctggccgt gcgctggttc      120

tttgcacact cctccgactc ccaggaggcc ttgatggtga agatgaccaa gctccgggtg      180

gtgcagtact atgggaattt cagccgcagc gccaaacggc ggaggctgcg cctgctggag      240

gagcagcggg gggcgctcta caggctctcc gtcttgacac tgcagccctc cgatcaaggg      300

cattacgtct gcagagtcca ggaaatcagc aggcacagga acaagtggac ggcctggtcc      360

aatggctcct cagccacgga aatgagagtc atttccctca aagcttctga agagtcatcc      420

tttgagaaaa caaaagagac ttgggcattt tttgaagatc tctatgtgta t               471


<210>  4471
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4471
ttacaatcac agggagtatc tctttacatt ccccaggcca caatcaatgc cacggtcaag       60

gaggatatac tgctaagcgt tgaatactcc tgtcacggag tccccactat cgaatggacc      120

tatagtagta actggggcac acagaagata gtggagtgga agccagggac gcaagcaaac      180

ataagccagt cccacaagga cagagtatgc acatttgata acggtagcat ccagctattc      240

tccgttggcg tccgtgacag tggctattac gttattactg tcactgaacg tttagggtcc      300

agccaatttg ggacgatagt attacacgtt tctgagattc tatatgagga tctacac         357


<210>  4472
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4472
ctcatcattg gctttggtat ttcagggaga cactccatca cagtcactac tgtcgcctca       60

gctgggaaca ttggggagga tggaatcctg agctgcactt ttgaacctga catcaaactt      120

tctgatatcg tgatacaatg gctgaaggaa ggtgttttag gcttggtcca tgagttcaaa      180

gaaggcaaag atgagctgtc ggagcaggat gaaatgttca gaggccggac agcagtgttt      240

gctgatcaag tgatagttgg caatgcctct ttgcggctga aaaacgtgca actcacagat      300

gctggcacct acaaatgtta tatcatcact tctaaaggca aggggaatgc taaccttgag      360

tataaaactg gagccttcag catgccggaa gtgaatgtgg actataatgc cagctcagag      420

accttgcggt gtgaggctcc ccgatggttc ccccagccca cagtggtctg ggcatcccaa      480

gttgaccagg gagccaactt ctcggaagtc tccaatacca gctttgagct gaactctgag      540

aatgtgacca tgaaggttgt gtctgtgctc tacaatgtta cgatcaacaa cacatactcc      600

tgtatgattg aaaatgacat tgccaaagca acaggggata tcaaagtgac agaatcggag      660

atcaaaaggc ggagtcacct acagctgcta aactcaaagg cttct                      705


<210>  4473
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  4473
gagcgcggtc caccagcatc agccccccga ggggacctga tgttcctgct ggacagctca       60

gccagcgtct ctcactacga gttctcccgg gttcgggagt ttgtggggca gctggtggct      120

ccactgcccc tgggcaccgg ggccctgcgt gccagtctgg tgcacgtggg cagtcggcca      180

tacaccgagt tccccttcgg ccagcacagc tcgggtgagg ctgcccagga tgcggtgcgt      240

gcttctgccc agcgcatggg tgacacccac actggcctgg cgctggtcta tgccaaggaa      300

cagctgtttg ctgaagcatc aggtgcccgg ccaggggtgc ccaaagtgct ggtgtgggtg      360

acagatggcg gctccagcga ccctgtgggc ccccccatgc aggagctcaa ggacctgggc      420

gtcaccgtgt tcattgtcag caccggccga ggcaacttcc tggagctgtc agccgctgcc      480

tcagcccctg ccgagaagca cctgcacttt gtggacgtgg atgacctgca catcattgtc      540

caagagctga ggggctccat tctcgacgcg atgcggccgc agcagctcca tgccacggag      600

atcacgtcca gcggcttccg cctggcctgg ccacccctgc tgaccgcaga ctcgggctac      660

tatgtgctgg agctggtgcc cagcgcccag ccgggggctg caagacgcca gcagctgcca      720

gggaacgcca cggactggat ctgggccggc ctcgacccgg acacggacta cgacgtggcg      780

ctagtgcctg agtccaacgt gcgcctcctg aggccccaga tcctgcgggt gcgcacgcgg      840

cccggtgagg cagggccggg ggcttcgggc ccggagtcgg gggctgggcc ggcccccacg      900

cagctcgccg ccctccccgc cccagaggag gccgggccag agcgcatcgt catctcccac      960

gcccggccgc gcagcctccg cgtgagttgg gccccagcgc tgggctcagc cgcggcgctc     1020

ggctaccacg tgcagttcgg gccgctgcgg ggcggggagg cgcagcgggt ggaggtgccc     1080

gcgggccgca actgcaccac gctgcagggc ctggcgccgg gcaccgccta cctggtgacc     1140

gtgaccgccg ccttccgctc gggccgcgag agcgcgctgt ccgccaaggc ctgcacgccc     1200

gacggcccgc gcccgcgccc acgccccgtg ccccgcgccc cgaccccggg gaccgccagc     1260

cgtgagccg                                                             1269


<210>  4474
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  4474
atggaggcac atgtgttcca gaaggactgg acggctacca gtgcctctgc ccgctggcct       60

ttggagggga ggctaactgt ggtagccctg aagctgagcc tggaatgcag ggtcgacctc      120

ctcttcctgc tggacagctc tgcgggcacc actctggacg gcttcctgcg ggccaaagtc      180

ttcgtgaagc ggtttgtgcg ggccgtgctg agcgaggact ctcgggcccg agtgggtgtg      240

gccacataca gcagggagct gctggtggcg gtgcctgtgg gggagtacca ggatgtgcct      300

gacctggtct ggagcctcga tggcattccc ttccgtggtg gccccaccct gacgggcagt      360

gccttgcggc aggcggcaga gcgtggcttc gggagcgcca ccaggacagg ccaggaccgg      420

ccacgtagag tggtggtttt gctcactgag tcacactccg aggatgaggt tgcgggccca      480

gcgcgtcacg caagggcgcg agagctgctc ctgctgggtg taggcagtga ggccgtgcgg      540

gcagagctgg aggagatcac aggcagccca aagcatgtga tggtctactc ggatcctcag      600

gatctgttca accaaatccc tgagctgcag gggaagctgt gcagccggca gcggccaggg      660

tgccggacac aagccctgga cctcgtcttc atgttggaca cctctgcctc agtagggccc      720

gagaattttg ctcagatgca gagctttgtg agaagctgtg ccctccagtt tgaggtgaac      780

cctgacgtga cacaggtcgg cctggtggtg tatggcagcc aggtgcagac tgccttcggg      840

ctggacacca aacccacccg ggctgcgatg ctgcgggcca ttagccaggc cccctaccta      900

ggtggggtgg gctcagccgg caccgccctg ctgcacatct atgacaaagt gatgaccgtc      960

cagaggggtg cccggcctgg tgtccccaaa gctgtggtgg tgctcacagg cgggagaggc     1020

gcagaggatg cagccgttcc tgcccagaag ctgaggaaca atggcatctc tgtcttggtc     1080

gtgggcgtgg ggcctgtcct aagtgagggt ctgcggaggc ttgcaggtcc ccgggattcc     1140

ctgatccacg tggcagctta cgccgacctg cggtaccacc aggacgtgct cattgagtgg     1200

ctgtgtggag gtgagtgggg gaatccacac cctcagggct gcccccatgg caggccctca     1260

gcc                                                                   1263


<210>  4475
<211>  2802
<212>  DNA
<213>  Homo Sapiens

<400>  4475
cgaggctaca ccgggaggaa gccgcccggg cacttcgcgg ccgagagacg ccgactgggc       60

ccccacgtct gcctctctgg gtttgggagt ggctgctgcc ctggctgggc gccctctatg      120

ggtggtgggc actgcaccct gcccctctgc tccttcggct gtgggagtgg catctgcatc      180

gctcccaatg tctgctcctg ccaggatgga gagcaagggg ccacctgccc agaaacccat      240

ggaccatgtg gggagtacgg ctgtgacctt acctgcaacc atggaggctg tcaggaggtg      300

gcccgagtgt gccccgtggg cttctcgatg acggagacag ctgttggcat caggtgtaca      360

gacattgacg aatgtgtaac ctcctcctgc gagggccact gtgtgaacac agaaggtggg      420

tttgtgtgcg agtgtgggcc gggcatgcag ctgtctgccg accgccacag ctgccaagac      480

actgacgaat gcctagggac tccctgtcag cagagatgta aaaacagcat tggcagctac      540

aagtgttcct gtcgaactgg cttccacctt catggcaacc ggcactcctg tgtagatgta      600

aacgagtgtc ggaggccatt ggagaggcga gtctgtcacc attcctgcca caacaccgtg      660

ggcagcttcc tatgcacatg ccgacctggc ttcaggctcc gagctgaccg cgtgtcctgt      720

gaagctttcc cgaaagccgt gctggcccca tctgccatcc tgcaaccccg gcaacacccg      780

tccaagatgc ttctgttgct tcctgaggcc ggccggcctg ccctgtcccc aggacatagc      840

cctccttctg gggctccagg gcccccagcc ggagtcagga ccacccgcct gccatctccc      900

accccacgac tacccacatc ctccccttct gcccctgtgt ggctgctgtc caccctgctg      960

gccaccccag tgcctactgc ctccctgctg gggaacctca gacccccctc actccttcag     1020

ggggaggtga tggggacccc ttcctcaccc aggggccctg agtccccccg actggcagca     1080

gggccctctc cctgctggca cctgggagcc atgcatgaat caaggagtcg ctggacagag     1140

cctgggtgtt cccagtgctg gtgcgaggac gggaaggtga cctgtgaaaa ggtgaggtgt     1200

gaagctgctt gttcccaccc aattccctcc agagatggtg ggtgctgccc atcgtgcaca     1260

ggctgttttc acagtggtgt cgtccgagct gaaggggatg tgttttcacc tcccaatgag     1320

aactgcaccg tctgtgtctg tctggctgga aacgtgtcct gcatctctcc tgagtgtcct     1380

tctggcccct gtcagacccc cccacagacg gattgctgta cttgtgttcc agtgagatgc     1440

tatttccacg gccggtggta cgcagacggg gctgtgttca gtgggggtgg tgacgagtgt     1500

accacctgtg tttgccagaa tggggaggtg gagtgctcct tcatgccctg ccctgagctg     1560

gcctgccccc gagaagagtg gcggctgggc cctgggcagt gttgcttcac ctgccaggag     1620

cccacaccct cgacaggctg ctctcttgac gacaacgggg ttgagtttcc gattggacag     1680

atctggtcgc ctggtgaccc ctgtgagtta tgcatctgcc aggcagatgg ctcggtgagc     1740

tgcaagagga cagactgtgt ggactcctgc cctcacccga tccggatccc tggacagtgc     1800

tgcccagact gttcagcagg ctgcacctac acaggcagaa tcttctataa caacgagacc     1860

ttcccgtctg tgctggaccc atgtctgagc tgcatctgcc tgctgggctc agtggcctgt     1920

tcccccgtgg actgccccat cacctgtacc taccctttcc accctgacgg ggagtgctgc     1980

cccgtgtgcc gagactgcaa ctacgaggga aggaaggtgg cgaatggcca ggtgttcacc     2040

ttggatgatg aaccctgcac ccggtgcacg tgccagctgg gagaggtgag ctgtgagaag     2100

gttccctgcc agcgggcctg tgccgaccct gccctgcttc ctggggactg ctgctcttcc     2160

tgtccagatt ccctgtctcc tctggaagaa aagcaggggc tctcccctca cggaaatgtg     2220

gcattcagca aagctggtcg gagcctgcat ggagacactg aggcccctgt caactgtagc     2280

tcctgtcctg ggcccccgac agcatcaccc tcgaggccgg tgcttcatct cctccagctc     2340

cttttaagaa cgaacttgat gaaaacacag actttaccta caagcccggc aggagctcat     2400

ggtccacact cactcgcttt ggggctgaca gccactttcc caggggagcc tggggcctcc     2460

cctcgactct caccagggcc ttcgacccct ccaggagccc ccactctacc tctagcttcc     2520

ccaggggctc ctcagccacc tcctgtgact ccagagcgct cgttctcagc ctctggggcc     2580

cagatagtgt ccaggtggcc tcctctgcct ggcaccctcc tgacggaagc ttcagcactt     2640

tccatgatgg accccagccc ctcgaagacc cccatcaccc tcctcgggcc tcgcgtgctt     2700

tctcccacca cctctagact ctccacagcc cttgcagcca ccacccaccc tggcccccag     2760

cagcccccag tgggggcttc tcggggggaa gagtccacca tg                        2802


<210>  4476
<211>  1587
<212>  DNA
<213>  Homo Sapiens

<400>  4476
gctggcttgc tgccagggct ggggagccac ccgggcgtgt gccccaacca gctcagcccc       60

aacctgtggg tggacgccca gagcacctgt gagcgcgagt gtagcaggga ccaggactgt      120

gcggctgctg agaagtgctg catcaacgtg tgtggactgc acagctgcgt ggcagcacgc      180

ttccccggca gcccagctgc gccgacgaca gcggcctcct gcgagggctt tgtgtgccca      240

cagcagggct cggactgcga catctgggac gggcagcccg tgtgccgctg ccgcgaccgc      300

tgtgagaagg agcccagctt cacctgcgcc tcggacggcc tcacctacta caaccgctgc      360

tatatggacg ccgaggcctg cctgcggggc ctgcacctcc acatcgtgcc ctgcaagcac      420

gtgctcagct ggccgcccag cagcccgggg ccgccggaga ccactgcccg ccccacacct      480

ggggccgcgc ccgtgcctcc tgccctgtac agcagcccct ccccacaggc ggtgcaggtt      540

gggggtacgg ccagcctcca ctgcgacgtc agcggccgcc cgccgcctgc tgtgacctgg      600

gagaagcaga gtcaccagcg agagaacctg atcatgcgcc ctgatcagat gtatggcaac      660

gtggtggtca ccagcatcgg gcagctggtg ctctacaacg cgcggcccga agacgccggc      720

ctgtacacct gcaccgcgcg caacgctgct gggctgctgc gggctgactt cccactctct      780

gtggtccagc gagagccggc cagggacgca gcccccagca tcccagcccc ggccgagtgc      840

ctgccggatg tgcaggcctg cacgggcccc acttccccac accttgtcct ctggcactac      900

gacccgcagc ggggcggctg catgaccttc ccggcccgtg gctgtgatgg ggcggcccgc      960

ggctttgaga cctacgaggc atgccagcag gcctgtgccc gcggccccgg cgacgcctgc     1020

gtgctgcctg ccgtgcaggg cccctgccgg ggctgggagc cgcgctgggc ctacagcccg     1080

ctgctgcagc agtgccatcc cttcgtgtac ggtggctgcg agggcaacgg caacaacttc     1140

cacagccgcg agagctgcga ggatgcctgc cccgtgccgc gcacaccgcc ctgccgcgcc     1200

tgccgcctcc ggagcaagct ggcgctgagc ctgtgccgca gcgacttcgc catcgtgggg     1260

cggctcacgg aggtgctgga ggagcccgag gccgccggcg gcatcgcccg cgtggcgctc     1320

gaggacgtgc tcaaggatga caagatgggc ctcaagttct tgggcaccaa gtacctggag     1380

gtgacgctga gtggcatgga ctgggcctgc ccctgcccca acatgacggc gggcgacggg     1440

ccgctggtca tcatgggtga ggtgcgcgat ggcgtggccg tgctggacgc cggcagctac     1500

gtccgcgccg ccagcgagaa gcgcgtcaag aagatcttgg agctgctgga gaagcaggcc     1560

tgcgagctgc tcaaccgctt ccaggac                                         1587


<210>  4477
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  4477
ctgccgccca tccgctattc ccacgccggc atctgcccca acgacatgaa tcccaacctc       60

tgggtggacg cacagagcac ctgcaggcgg gagtgtgaga cggaccagga gtgtgagacc      120

tatgagaagt gctgccccaa cgtatgtggg accaagagct gcgtggcggc ccgctacatg      180

gacgtgaaag ggaagaaggg cccagtgggc atgcccaagg aggccacatg tgaccacttc      240

atgtgtctgc agcagggctc tgagtgtgac atctgggatg gccagcccgt gtgtaagtgc      300

aaagaccgct gtgagaagga gcccagcttt acctgcgcct cggacggcct cacctactat      360

aaccgctgct acatggatgc cgaggcctgc tccaaaggca tcacactggc cgttgtaacc      420

tgccgctatc acttcacctg gcccaacacc agccccccac cacctgagac caccatgcac      480

cccaccacag cctccccaga gacccctgag ctggacatgg cggcccctgc gctgctcaac      540

aaccctgtgc accagtcggt caccatgggt gagacagtga gcttcctctg tgatgtggtg      600

ggccggcccc ggcctgagat cacctgggag aagcagttgg aggatcggga gaatgtggtc      660

atgcggccca accatgtgcg tggcaacgtg gtggtcacca acattgccca gctggtcatc      720

tataacgccc agctgcagga tgctgggatc tacacctgca cggcccggaa cgtggctggg      780

gtcctgaggg ctgatttccc gctgtcggtg gtcaggggtc atcaggctgc agccacctca      840

gagagcagcc ccaatggcac ggctttcccg gcggccgagt gcctgaagcc ccccgacagt      900

gaggactgtg gcgaagagca gacccgctgg cacttcgatg cccaggccaa caactgcctg      960

accttcacct tcggccactg ccaccgtaac ctcaaccact ttgagaccta tgaggcctgc     1020

atgctggcct gcatgagcgg gccgctggcc gcgtgcagcc tgcccgccct gcaggggccc     1080

tgcaaagcct acgcgcctcg ctgggcttac aacagccaga cgggccagtg ccagtccttt     1140

gtctatggtg gctgcgaggg caatggcaac aactttgaga gccgtgaggc ctgtgaggag     1200

tcgtgcccct tccccagggg gaaccagcgc tgtcgggcct gcaagcctcg gcagaagctc     1260

gttaccagct tctgtcgcag cgactttgtc atcctgggcc gagtctctga gctgaccgag     1320

gagcctgact cgggccgcgc cctggtgact gtggatgagg tcctaaagga tgagaaaatg     1380

ggcctcaagt tcctgggcca ggagccattg gaggtcactc tgcttcacgt ggactgggca     1440

tgcccctgcc ccaacgtgac cgtgagcgag atgccgctca tcatcatggg ggaggtggac     1500

ggcggcatgg ccatgctgcg ccccgatagc tttgtgggcg catcgagtgc ccgccgggtc     1560

aggaagcttc gtgaggtcat gcacaagaag acctgtgacg tcctcaagga gtttcttggc     1620

ttgcac                                                                1626


<210>  4478
<211>  1053
<212>  DNA
<213>  Homo Sapiens

<400>  4478
gggccgccgc aggaggagag cctgtaccta tggatcgatg ctcaccaggc aagagtactc       60

ataggatttg aagaagatat cctgattgtt tcggagggga aaatggcacc ttttacacat      120

gatttcagaa aagcgcaaca gagaatgcca gctattcctg tcaatatcca ttccatgaat      180

tttacctggc aagctgcagg gcaggcagaa tacttctatg aattcctgtc cttgcgctcc      240

ctggataaag gcatcatggc agatccaacc gtcaatgtcc ctctgctggg aacagtgcct      300

cacaaggcat cagttgttca agttggtttc ccatgtcttg gaaaacagga tggggtggca      360

gcatttgaag tggatgtgat tgttatgaat tctgaaggca acaccattct caaaacacct      420

caaaatgcta tcttctttaa aacatgtcaa caagctgagt gcccaggcgg gtgccgaaat      480

ggaggctttt gtaatgaaag acgcatctgc gagtgtcctg atgggttcca cggacctcac      540

tgtgagaaag ccctttgtac cccacgatgt atgaatggtg gactttgtgt gactcctggt      600

ttctgcatct gcccacctgg attctatgga gtgaactgtg acaaagcaaa ctgctcaacc      660

acctgcttta atggagggac ctgtttctac cctggaaaat gtatttgccc tccaggacta      720

gagggagagc agtgtgaaat cagcaaatgc ccacaaccct gtcgaaatgg aggtaaatgc      780

attggtaaaa gcaaatgtaa gtgttccaaa ggttaccagg gagacctctg ttcaaagcct      840

gtctgcgagc ctggctgtgg tgcacatgga acctgccatg aacccaacaa atgccaatgt      900

caagaaggtt ggcatggaag acactgcaat aaaaggtacg aagccagcct catacatgcc      960

ctgaggccag caggcgccca gctcaggcag cacacgcctt cacttaaaaa ggccgaggag     1020

cggcgggatc cacctgaatc caattacatc tgg                                  1053


<210>  4479
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  4479
gtagggagtg aagtctcaga taagaggacc tgtgtgagcc tcactaccca gcgactgccg       60

gttagcagaa tcaagaccta caccatcacg gaaggctcct tgagagcagt aatttttatt      120

accaaacgtg gcctaaaagt ctgtgctgat ccacaagcca catgggtgag agacgtggtc      180

aggagcatgg acaggaaatc caacaccaga aataacatga tccagaccaa gccaacagga      240

acccagcaat cgaccaatac agctgtgact ctgactggc                             279


<210>  4480
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  4480
gtagggagtg aagtctcaca taggaggacc tgtgtgagcc tcactaccca gcgactgcca       60

gttagcagaa tcaagaccta caccatcacg gaaggctcct tgagagcagt aatttttatt      120

accaaacgtg gcctaaaagt ctgtgctgat ccacaagcca cgtgggtgag agacgtggtc      180

aggagcatgg acaggaaatc caacaccaga aataacatga tccagaccaa gccaacagga      240

acccagcaat cgaccaatac agctgtgacc ctgactggc                             279


<210>  4481
<211>  921
<212>  DNA
<213>  Homo Sapiens

<400>  4481
cacttggttc gattaccaag agcttttcgc ttgaccaaag attcagtgaa aatagtggga       60

tcaacaagtt ttccagtgaa agcgtatgtc atgctccatc aaaagagtcc acacgtgtta      120

tgtgtaacgc aacaactgcg aaatgctgaa ctgatagacc catcattcca atggtatggg      180

cctaaaggaa aagttgtttc agtagaaaac cgcactgcac aaataacatc cacaggaagc      240

cttgtattcc aaaattttga ggagagtatg agtggaattt atacatgttt cctcgaatat      300

aaacctactg tggaagaaat tgttaaacgt cttcaactaa aatatgctat atatgcttat      360

cgtgagcctc attattatta tcagttcaca gctcgatatc atgcagctcc ctgcaatagc      420

atttataata tttcttttga gaagaaactt cttcagattt taagcaaact gcttcttgac      480

ctttcatgtg aaatttcctt acttaagtct gaatgccatc gcgttaaaat gcaaagagct      540

ggtttgcaaa atgaattgtt ctttgcattt tcagtttcat ctctagacac tgaaaaagga      600

cccaagcgat gtacagacca taactgtgaa ccttacaaaa gactttttaa ggctaaaaat      660

ctcatagaga gattttttaa tcaacaagta gaaattcttg gcagacgtgc agaacaatta      720

cctcaaatat actatattga aggtactctc caaatggttt ggattaatcg ctgctttcca      780

ggatatggaa tgaatgtcca gcaacatcca aaatgtcctg agtgctgtgt gatctgcagc      840

cctggatcat ataacccccg tgatggaatt cattgccttc aatgcaatag cagcctggtg      900

tatggagcaa aaacgtgctt a                                                921


<210>  4482
<211>  897
<212>  DNA
<213>  Homo Sapiens

<400>  4482
gacaaaatat atgtagagtt acatcaaaat agtccagtcc ttatctgtat ggattttaag       60

ctttctaaaa aagaaatagt ggaccccacc tacttatgga ttgggcctaa tgaaaagacg      120

ttaacaggaa ataatagaat aaatataact gaaactggac agctgatggt gaaagatttt      180

ttggagcctt tgtctggact ttacacatgt actctttctt ataagactgt taaagcagaa      240

actcaagaag aaaaaacagt caaaaagaga tatgacttta tggtctttgc ctatcgggaa      300

cctgattatt catatcagat ggctgtacgt tttaccacaa ggtcttgtat agggagatac      360

aatgatgtat tctttagagt gctgaagaaa atcttggata gtctaatttc tgatttgtca      420

tgccatgtca tagagccatc atataaatgc cattctgttg aaattccaga acatggcctc      480

atacatgagc tatttatagc atttcaagtt aatccttttg cgccggggtg gaaaggtgct      540

tgcaatggat ctgttgactg tgaagatacc actaatcata atatcctcca ggcaagagat      600

cgaatagaag acttttttcg gagccaagca tatattttct accataactt taataaaact      660

ctaccagcaa tgcattttgt ggaccacagt ttgcaagtag tacgtctgga tagctgtcga      720

ccaggctttg gaaaaaatga acgtctacac agtaattgcg ctagctgttg tgtggtttgt      780

agtcctgcga cttttagtcc tgatgttaat gtaacttgtc agacctgcgt ttccgtcctt      840

acctatggag ctaaatcttg cccacaaact tcaaacaaaa atcagcaata tgaagat         897


<210>  4483
<211>  930
<212>  DNA
<213>  Homo Sapiens

<400>  4483
atgaacggtc tgtctttgtc agagctgtgt tgcctgttct gttgtccacc ctgtcccgga       60

aggatagctg ccaaactggc cttcctgcct ccggaggcaa catattccct ggttcctgaa      120

cccgaacctg gtcccggagg agctggggcc gcccccctgg gtacacttag ggccagctcc      180

ggtgctcctg gccggtggaa attgcacttg accgagcgag cagactttca gtacagccaa      240

cgcgaactgg acactattga agtcttcccc accaagtctg cacggggtaa cagggtttca      300

tgcatgtacg tgagatgcgt acctggcgca agatatacag tgttgttttc ccatggcaac      360

gccgttgacc tgggtcagat gagttctttc tacattggac tcggtagcag gctgcactgc      420

aatatttttt catacgatta ctctggctat ggagcctcca gtgggcggcc atctgaacga      480

aatttatacg ccgatatcga cgccgcttgg caggccctcc ggacaagata tggcatcagc      540

ccggactcca ttattctcta tgggcagagt attggtaccg ttccaacagt agatttggcg      600

tctcggtacg aatgtgccgc tgtcgtcctg cactctcccc tcacctctgg catgcgcgtc      660

gccttcccgg atactaaaaa aacttactgc tttgacgcat tcccgaatat cgaaaaggtt      720

agtaagatta caagtccggt tctcataatc cacggtacag aggatgaagt gatagacttt      780

tcccacggtc tcgctctgta tgagaggtgt cccaaagcag tggagccgct gtgggtcgaa      840

ggtgccgggc acaacgatat cgaactgtat agccagtatc tggagcgact tcggagattt      900

atatcacagg aattaccctc ccagagggct                                       930


<210>  4484
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  4484
atgaacaatc tctcattcag cgaactgtgt tgtctgtttt gctgcccccc ctgtccaggg       60

aagattgcgt ccaaactggc ttttctgcct cccgacccga cctacactct gatgtgtgac      120

gaaagtggtt cccgctggac actgcacctc agtgaacggg ctgactggca atacagctct      180

cgagaaaaag atgccatcga gtgttttatg accagaacca gcaaggggaa taggatcgcc      240

tgtatgttcg tcagatgctc cccgaacgcc aagtacacac tgctcttttc ccacggaaac      300

gccgtggatc tggggcagat gtccagcttt tacattgggc tcggaagccg tatcaattgt      360

aacattttca gttacgacta ctcaggctat ggtgcctcaa gcggcaaacc aaccgagaag      420

aacctctacg cggacatcga ggcagcttgg ctggctctga gaactcgcta tgggatccgc      480

cccgagaacg taattatcta cggccaatcc atcgggaccg taccaagtgt tgacttggca      540

gccagatacg aatcagccgc ggtcattctc cattctccat tgactagtgg catgagagtt      600

gcgtttccag ataccaagaa gacgtattgt tttgatgcct tccctaatat agacaaaatt      660

agcaaaatca cttctcccgt cctcatcata cacggaacgg aagacgaagt tatagacttc      720

tcccacggcc tcgccctttt cgaacgatgt cagagacccg tggagcctct gtgggtggaa      780

ggagcagggc ataatgatgt ggagctgtac gggcaatacc ttgagcgact gaagcagttc      840

gtgagccagg aactggttaa cttg                                             864


<210>  4485
<211>  1170
<212>  DNA
<213>  Homo Sapiens

<400>  4485
aggccagagg acctgaaacg cctgttcgag tttcgtaaga tgatcggtaa ccgcgaacga       60

tgccaaaact tggtgagcag tgattatcca gtccacatcg acaagattga ggagcagtca      120

gactgcaaaa tcctcgacgg tcattttgtg tcccccatgg cccactatgt acctgacatc      180

atgccaattg aatccgtaat cgcccggttc cagtttattg tgcccaagga gtggaattcc      240

aagtaccggc ccgtatgcat tcacctggcg ggaacaggcg atcaccacta ttggcgcaga      300

cggaccctta tggcacgccc aatgattaag gaggcgcgta tggcctcact tcttctggag      360

aacccgtatt atgggtgcag aaagcccaag gatcaggtcc gttccagttt aaagaacgtt      420

tctgatctgt ttgtgatggg tggtgccctt gtgttagagt ccgctgctct tctgcattgg      480

ctcgagaggg aaggatacgg gccactcgga atgaccggaa tcagcatggg aggacatatg      540

gctagcttag cggtgtctaa ctggccgaag cccatgcccc tcataccatg tctgagttgg      600

agtaccgcaa gcggagtgtt caccacaacc gacagtttta agatgggtca ggagttcgtc      660

aagcatttca catcttccgc tgacaagctt actaacctga acctggtttc ccgcactctc      720

aatctcgaca tttccaacca agttgtctca caaaagccgg ctgattgcca caatagtagc      780

aaaacttccg tctccgccac aagtgagggg ctcttactgc aggatacaag taaaatgaag      840

aggtttaatc agaccctcag cacaaacaag tctggataca cttcaaggaa ccctcagtca      900

taccatctgc tgagcaagga acagtcccgg aactccctga gaaaggagtc actgatcttc      960

atgaagggtg tgatggacga gtgcacccac gttgcaaatt tctcagtacc agtggatcca     1020

agtctgatta ttgttgttca ggctaaggag gacgcttaca tccctaggac cggggtccgg     1080

tctctgcagg agatatggcc cgggtgtgag atcagatacc ttgagggcgg acatatctct     1140

gcttacttgt ttaaacaggg actgttcagg                                      1170


<210>  4486
<211>  567
<212>  DNA
<213>  Homo Sapiens

<400>  4486
gcgtcatgga catctcgtca ggtaggagaa cggacactta ccggcattgt aatagactca       60

ggcgatggag tgacccacgt gattcctgtg gcagaaggtt atgttattgg cagctgtatt      120

aagcacatcc ctattgctgg ccgggacatc acatatttta tccagcaact gctgcgcgag      180

agggaggtgg gcattccccc agaacaatct ctggagactg ccaaggcgat taaagagaag      240

tactgctata tctgtcctga tatcgtgaaa gagtttgcca aatatgacgt ggaccctcag      300

aaatggatta aacaatacac agggattaat gccatcaatc aaaaaaagtt cgtgatagat      360

gtcggctacg agcggtttct gggtcccgag atcttttttc acccagaatt cgccaaccct      420

gattccatgg aatctatcag tgatgtagtg gacgaagtta tacaaaactg ccccattgac      480

gtccggcgcc ccttgtataa aatggaacag attcctctgt catacccaca gggccacggc      540

tttcatccat tatccccacc gttccac                                          567


<210>  4487
<211>  795
<212>  DNA
<213>  Homo Sapiens

<400>  4487
aaaagccccg agaaagagga ttttcttcgc gctcaaaagt acatcgacct gtaccttgtc       60

ctcgataatg cgttctataa gaactacaac gagaatctta cgctgatccg cagtttcgta      120

tttgacgtga tgaacctcct caacgttatt tacaatacca tcgacgtcca agtggccctc      180

gtgggcatgg agatttggtc tgacggcgac aaaattaagg tggtgcctag tgcctctacc      240

acctttgata attttctgcg gtggcacagc tctaacctgg ggaaaaaaat tcatgatcat      300

gcgcaattgc tcagcgggat ctccttcaat aatcgaagag tgggtctcgc cgcttccaat      360

agtttatgca gccctagttc tgtcgccgtg atcgaagcca aaaagaagaa caacgtggcc      420

ttggtgggtg tgatgagtca cgagttgggc catgtcctcg gcatgccaga tgtgccattc      480

aatactaagt gtcccagtgg ttcttgcgtg atgaatcagt atctgtcttc taagttccca      540

aaagacttca gcactagctg tagggctcac tttgagaggt atctgctgag ccagaagccc      600

aagtgcttgc tccaggcccc catcccaacc aacataatga cgacacctgt gtgtgggaac      660

catctcttag aagtgggcga ggattgcgac tgcggaagtc ccaaagagtg cacgaacctt      720

tgctgcgagg cactgacctg caagcttaag ccaggaactg actgtggggg tgacgcccct      780

aaccacacga cggaa                                                       795


<210>  4488
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  4488
caaggaccag gagagtggac cccatgggtg agctggacca gatgcagttc ctcctgcggc       60

aggggcgtga gcgttcggag ccgtaggtgc ctccggctcc cgggagagga accctgctgg      120

ggcgatagcc acgaatatcg tctgtgccag cttcccgact gtccacctgg cgcagttcct      180

tttagagacc tgcagtgtgc tctgtacaac ggcaggcccg tcctcggtac tcagaaaaca      240

taccagtggg tgccattcca cggggcgcct aaccagtgcg atctcaattg cttagctgag      300

gggcatgctt tctaccactc ctttggcagg gttctggatg ggaccgcttg ttctcctgga      360

gcccaaggcg tgtgtgtggc tgggcgatgt ctctctgctg gatgcgatgg gctgttaggc      420

tccggcgccc tggaggatag atgtggacgg tgcgggggcg ctaatgattc ctgtttattt      480

gtgcaacgcg tttttcggga tgcaggcgca ttcgctggat attggaacgt tacactcata      540

cccgagggcg ctaggcatat ccgggtcgag cacaggtcta gaaaccattt ggctctgatg      600

ggcggggacg ggcggtatgt gcttaacgga cactgggtag tgagcccccc tggcacatat      660

gaggccgcag gaacgcacgt cgtgtatact agggacacag gtcctcagga aacactccag      720

gctgccggac cgacatctca tgatttgctc ctccaggtcc ttctccagga acctaacccc      780

ggaatagagt ttgagttctg gctgccgcga gagcgctata gccctttcca ggcgagagtg      840

caagccctgg ggtggccact gcgccagcca caacctcgcg gtgtggagcc acagccgcca      900

gcagcccccg ctgtaacgcc cgcacaaact ccaacactcg ctcccgatcc ctgcccacca      960

tgtccggata cgagaggaag agcccacagg ctgctgcact actgcggcag cgactttgtc     1020

tttcaggcac gtgtgctggg acaccatcac caagctcagg aaacacgata tgaagtgcgg     1080

atccagttgg tgtacaaaaa taggtctcct ctgcgggctc gcgaatacgt atgggctccc     1140

ggacactgtc cttgccccat gctcgcacca caccgggact acttgatggc cgtgcagcga     1200

ctcgtctccc ctgatggcac ccaggatcag ctgctcctcc cacatgcagg ctatgcccga     1260

ccatggagtc cagctgagga cagtcgcatc cgcctgacgg cccgacggtg tcctgga        1317


<210>  4489
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  4489
atgtggatcc agcagttact cggcttgtca tccatgagta tcaggtggcc aggcaggccc       60

ttaggctctc atgcttggat cctcatcgca atgttccaac tggctgtaga tctgcctgca      120

tgtgaggcat taggaccagg tcctgaattt tggcttctgc ctagatctcc gccgcggccg      180

cccaggttgt ggagttttag gagcggtcaa cctgctagag tccctgcccc cgtctggtca      240

ccccggccac ccagagtaga aaggatccat ggacagatgc agatgccccg cgctcggcgt      300

gcgcaccgcc cccgggacca ggccgctgct ctcgtgccaa aagctgggct cgctaagcct      360

cctgccgccg caaaatcttc tccttcactc gcttcttcat catcctcatc ttcttctgcg      420

gtggccgggg gggcccccga gcagcaagcc ctccttcgcc gcggcaagag gcatctgcag      480

ggcgacggcc tgtcttcatt tgactctcgg ggctcccggc ctaccacaga aacagaattc      540

atagcgtggg gcccaaccgg ggacgaggaa gccttagaga gtaacacttt ccccggggtg      600

tacggcccaa ctaccgtgtc aatcttgcag acacgtaaaa ctaccgttgc cgccacaacc      660

accactacta cgactgcgac acctatgact ctccaaacca aagggttcac tgagagtctc      720

gacccacgtc gccgcattcc cggaggggtg agcactaccg aaccaagcac ttctccgtcc      780

aataacggtg aggtcaccca acccccgagg atcctggggg aggcgagcgg gctggcggtg      840

caccag                                                                 846


<210>  4490
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  4490
ggcgctgagc ctcgagagcc tgccgatggg caggcgctgc tgagattggt ggtggagctg       60

gtgcaggaac tgcgtaaaca ccactctgcc gaacataagg ggttgcagtt gctcggtagg      120

gactgcgcct tagggcgagc ggaagcagcc ggcttagggc ctagtccgga gcagagggta      180

gagattgttc cgagggacct caggatgaag gacaaatttc tgaagcactt aaccgggccc      240

ctttattttt ccccaaaatg ctctaaacat tttcatcgac tgtatcacaa tactagagat      300

tgtacgatcc ctgcctacta caaacgctgt gctagactgc tgacacggct ggcggtcagt      360

cctgtgtgta tggaagataa gcaa                                             384


<210>  4491
<211>  1605
<212>  DNA
<213>  Homo Sapiens

<400>  4491
cgggcagaag aaccagcagt aggaacatcc ggtctgattt ttagggaaga cctggattgg       60

ccacccgggt ctccccaaga gcccttgtgc ttagtagcac tgggtgggga cagcaatggt      120

tctagtagcc ccttgcgcgt ggtgggagct ctgagcgcct acgagcaggc ttttctgggt      180

gccgttcaaa gagcgcgatg gggtccgagg gatctggcaa cattcggggt ctgcaatacc      240

ggcgaccggc aggcagcctt gcctagcctc cggcggcttg gagcctggct tcgtgatccc      300

ggaggtcaga gactggtggt gctgcatctg gaggaggtta cctgggaacc tacgccttca      360

ctgagattcc aagagccgcc acccggaggg gcaggtcccc ccgaactggc tctgttagtg      420

ttatatcccg gacccgggcc tgaggtaacg gtgaccagag caggccttcc tggagcacag      480

tccttgtgtc cttctcgaga tacccgttac ctcgttttgg cggttgatag gcctgctggt      540

gcctggaggg gctctggtct ggccctcact ttacagccgc gcggggaaga ctcacggctc      600

tccacggcta gactgcaggc cctgcttttt ggggatgacc acaggtgttt caccaggatg      660

acaccagccc tgctgctgct gcctagatct gagcccgctc ccttacccgc acacggccag      720

ctggataccg tccccttccc gcctccgagg ccttctgctg agcttgagga gagcccccca      780

tcagctgacc catttcttga gacactcact aggctggtga gagccctcag ggtgcccccc      840

gccagggcat ccgcgccaag gctggcactg gatccggatg ccctggctgg tttccctcag      900

gggctcgtaa atctgagcga cccagccgcg ctcgagcggt tgttagacgg cgaagaaccc      960

ctgcttctcc tgcttagacc aaccgcggct accaccgggg atccagctcc cctgcatgac     1020

cctacatccg caccctgggc cacagccctg gctcggcgcg tggcggcgga gttgcaggca     1080

gccgccgctg aactgcgcag tcttcccggc cttcctcctg ccactgctcc tctgctggcc     1140

cggctgctgg cactgtgccc aggagggcct ggggggctcg gagatcctct cagagccctg     1200

ctgctcctta aagcactgca gggtcttcgg gtagagtggc gtggtcgtga cccgcggggg     1260

cctgggcgtg cgcagaggag cgcaggtgct acagccgcag atggcccgtg cgctctgagg     1320

gaactttccg tcgacctgag ggccgagcga agcgtgttga ttccagagac ttaccaggcc     1380

aacaactgcc agggggtctg tgggtggcct cagagtgaca gaaatccaag gtatgggaat     1440

cacgtggtgc ttctcctgaa gatgcaggtt cggggcgccg ccctggcccg gcccccttgc     1500

tgcgtgccaa ctgcttacgc agggaagctc ttgataagtt tgtcagaaga aagaattagc     1560

gctcaccacg tccccaacat ggtggccacc gagtgcggct gcaga                     1605


<210>  4492
<211>  1014
<212>  DNA
<213>  Homo Sapiens

<400>  4492
gtcagtaagc tctgggtccc aaacacagac ttcgacgtag ccgctaattg gtctcagaac       60

agaacgccat gtgccggcgg ggccgtcgag ttcccagccg ataaaatggt gtccgttctc      120

gtccaagaag gccacgcggt ttcagacatg ctgctcccat tggacggcga gctggtcctc      180

gcatcaggtg ccggatttgg ggtaagcgat gtaggaagtc accttgattg cggcgccggc      240

gagcctgcag tctttcgtga ctcagatcgg ttttcttggc acgacccaca cctctggcga      300

agtggtgatg aggcccctgg cttgttcttc gtggatgcag aacgcgtccc atgtcgccac      360

gacgatgtgt tcttcccacc tagcgcatcc tttcgagtcg gattaggtcc tggggcctcc      420

cctgtcaggg tccgttccat ctcagcgtta ggtcgaacgt ttacaaggga cgaagatctc      480

gcagtctttc tggctagccg tgccgggcgg ttaagatttc acggtcccgg agcactctca      540

gtaggtcccg aggactgcgc cgacccatct ggctgtgtct gcggtaatgc cgaggctcag      600

ccatggatct gcgctgctct gctgcaaccc ctcggcggcc gctgccctca agctgcttgc      660

catagcgcgc tgcggcctca ggggcagtgc tgcgatttat gcggagccgt agtgctgctg      720

actcatggcc cggctttcga cctcgagagg taccgggcaa ggatcctgga tacattcctt      780

gggttacctc agtaccacgg actgcaggtc gcggtttcaa aagtgccgag gtcatctcgg      840

ttgcgtgagg ccgacaccga gattcaggtc gtgctggtgg aaaacgggcc cgaaacaggt      900

ggcgcaggca ggcttgctcg ggctctgctg gccgacgtcg cagagaatgg cgaggctctg      960

ggggtgctgg aagcgactat gcgcgaatca ggcgctcacg tctggggatc tagc           1014


<210>  4493
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  4493
cagtatagcc ctaatacgca acaggggaga acgtctatag tccacctgtt cgagtggcgc       60

tgggtcgaca tagccctcga atgcgaaagg tacctggccc cgaaaggatt tggcggggtg      120

caggtttccc cgcctaacga aaatgtggcc atctacaatc catttcgtcc ctggtgggag      180

cgctatcaac ctgtgagtta taagttgtgc actaggagcg ggaatgagga tgaattccgg      240

aacatggtga cgcgctgcaa taatgtaggt gtacgcatat atgtggacgc cgtgataaat      300

catatgtgcg gaaatgctgt gtcagcaggt acaagttcca cttgtggttc ctactttaac      360

cctgggagca gagacttccc tgctgtgccc tactctggct gggatttcaa tgatgggaag      420

tgcaagaccg gtagtggcga catagaaaac tataacgacg caacacaggt ccgcgattgt      480

cggttgacag gcctcttgga tctcgctctg gagaaagact atgtgcggtc aaaaattgcc      540

gaatacatga accacctgat cgacatcggt gtagctggct ttcggctgga tgcatccaag      600

cacatgtggc ccggggatat caaagccatc cttgataaac tgcacaatct caattccaat      660

tggtttccgg ccggatccaa accttttatt taccaagaag tgatcgattt ggggggggag      720

cctataaaga gcagcgatta tttcggcaat gggagagtta cagaatttaa atatggcgcc      780

aagcttggca ccgtaattag aaagtggaat ggtgagaaga tgtcatacct gaaaaactgg      840

ggagaggggt ggggattcgt gccctccgat agagcccttg ttttcgttga caatcatgat      900

aatcagcgcg ggcacggagc tggaggcgca tcaattctca ctttttggga tgcccgactc      960

tataaaatgg ccgtggggtt catgctggct cacccatatg gattcaccag agttatgtcc     1020

tcctaccgct ggcctcgcca gttccagaac ggtaacgatg tgaatgactg ggtgggcccc     1080

cctaataata atggagtgat caaggaggtc accatcaacc ctgataccac gtgtggcaat     1140

gattgggtct gcgagcaccg gtggcggcaa atcagaaata tggtcatctt cagaaacgtg     1200

gtcgacggcc aacccttcac taactggtac gacaatggaa gcaaccaagt agctttcggg     1260

agggggaatc ggggttttat tgtgtttaat aacgacgatt ggagcttcag tctgacactc     1320

cagacgggac ttcccgccgg aacgtattgc gacgtgatct ctggagataa aattaatggt     1380

aactgtacag gcataaaaat ttacgtgagc gacgacggta aagctcactt ttctatttcc     1440

aactcagccg aagacccctt catagcaata catgctgagt ccaagctc                  1488


<210>  4494
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  4494
caatatagcc caaatacaca acaggggagg accagcattg ttcacctctt cgaatggagg       60

tgggtggaca tcgctctgga atgcgagaga tatctcgccc ctaaggggtt tggaggcgtc      120

caagtttcac ctccgaacga gaacgtagcc atacataatc ctttcaggcc ctggtgggag      180

aggtatcagc cagtcagcta taagctctgc acacggtccg gaaacgaaga tgagtttcga      240

aacatggtga caaggtgcaa caatgtgggc gtgcggatct atgtagatgc cgttatcaac      300

catatgtctg ggaatgctgt gtcagccggc acctcttcta cctgcggtag ttatttcaac      360

ccaggctccc gtgacttccc tgccgttccc tacagcggtt gggacttcaa tgatgggaaa      420

tgtaaaactg gctccggcga catcgagaat tacaacgatg ctacacaggt tcgcgactgt      480

cgattagtcg gactgctgga tctggcctta gagaaggatt acgtgcgcag taagatcgcc      540

gaatatatga accacttaat cgatatcggg gtcgctgggt ttcgccttga tgcctcaaag      600

cacatgtggc caggggacat caaggcgatc ttggacaaac tccacaattt gaacagtaat      660

tggttcccag ccggaagcaa acctttcatc taccaggagg tgatcgatct tggcggagag      720

cccataaaaa gctccgatta cttcggcaac ggccgagtga ctgaattcaa gtacggggca      780

aagctgggaa ccgttattcg taaatggaat ggagagaaga tgtcctatct taagaattgg      840

ggcgaaggtt ggggattcat gcccagtgac agggccctcg ttttcgtgga caaccacgat      900

aatcagaggg ggcacggagc gggaggggca tccattttga ctttctggga tgcaaggctg      960

tacaagatgg ccgtcggatt catgttagca cacccatacg gcttcacgcg agtcatgagc     1020

agttacaggt ggccccggca gttccagaac ggaaatgatg tcaacgattg ggtggggcct     1080

ccaaataaca atggagtgat taaagaggtt acaatcaacc ccgacacaac ctgcggtaac     1140

gattgggttt gcgaacatag gtggcgccag atccgaaata tggtaaattt ccggaacgtg     1200

gtggacgggc agccttttac taattggtac gataacggaa gtaaccaagt tgcgttcggc     1260

cggggcaacc gaggtttcat agttttcaac aatgacgact ggaccttctc attaacactg     1320

cagaccgggt taccggctgg cacctactgc gatgtgattt caggcgacaa gattaacggc     1380

aattgtacag gaatcaaaat ctacgtgagc gacgacggca aagctcactt cagcatctct     1440

aacagtgccg aggacccttt tattgccatc cacgccgaat caaaactg                  1488


<210>  4495
<211>  1404
<212>  DNA
<213>  Homo Sapiens

<400>  4495
ggtcagttta aaataaaaaa gatcaatcag aggcgatacc ccagagctac agacgggaag       60

gaagaggcca aaaaatgcgc gtacactttt cttgtgcccg aacagcggat cactggaccc      120

atctgcgtca atacaaaagg acaagatgcc agtactatca aggatatgat tactagaatg      180

gatctggaaa atttgaaaga tgtgttgtcc cggcagaaac gcgagatcga cgtgctccag      240

ctggtggtag acgtggacgg aaatatcgtg aacgaggtga agcttctgag gaaagagtca      300

cggaacatga atagtcgagt cacccagctg tacatgcagc tgctgcacga gatcattaga      360

aaacgcgata attctctgga gctgtcccaa ctggagaaca aaatattgaa tgtcactacg      420

gagatgctga aaatggctac acgctatagg gaattagagg taaaatacgc ctccttgacc      480

gacctcgtga acaatcaatc cgtgatgatc accctgctgg aggaacagtg tctcagaatt      540

tttagcaggc aggacacgca tgtctcaccc ccactcgtgc aagtagtgcc acagcacatt      600

cccaattccc aacagtatac gcccggactc ctggggggaa acgaaatcca gagggaccct      660

ggttaccccc gcgacctgat gcccccacct gatctcgcta cttccccaac gaaatcacca      720

tttaagatcc ctcccgtgac gtttattaat gaagggccct tcaaagattg tcagcaggcg      780

aaggaagcag ggcacagcgt ctccggtatc tatatgatca aacctgagaa cagtaacggc      840

ccaatgcagc tctggtgtga aaactccctg gaccctggag gatggaccgt gattcaaaag      900

aggaccgacg gaagcgttaa ttttttcagg aattgggaaa attataagaa gggtttcggc      960

aacatcgacg gggagtactg gctcggcctc gagaacattt acatgttgtc taatcaagac     1020

aattataagt tgctgatcga gctcgaagac tggtctgata agaaggtgta tgccgaatat     1080

tcaagcttta gattggagcc tgagtcagaa ttttatcggc tgcgcctcgg cacctatcag     1140

ggtaatgccg gggactccat gatgtggcac aatggtaaac agtttaccac attggatagg     1200

gacaaagaca tgtatgccgg caactgcgct cacttccata agggcgggtg gtggtataac     1260

gcctgtgctc atagtaatct taacggcgtt tggtaccggg gaggtcacta tcggtccaaa     1320

caccaggacg gcattttttg ggcagagtat agaggaggta gctatagtct cagggctgtg     1380

cagatgatga ttaaacccat cgac                                            1404


<210>  4496
<211>  1089
<212>  DNA
<213>  Homo Sapiens

<400>  4496
aattgcgtgc atcacagcac cgactctagt gttgtcaaca tcgtcgaaga tggtagcaat       60

gccaaggacg agagtaagtc aaacgacact gtgtgcaagg aggattgcga agagagttgc      120

gacgtgaaga ctaaaatcac aagagaagaa aaacacttta tgtgtagaaa cctgcaaaac      180

agcatcgtat cttatacacg cagcactaaa aagctgttaa gaaacatgat ggatgagcag      240

caggctagcc tggattatct gtccaatcaa gttaatgagt taatgaacag ggtcttgtta      300

ctgacgactg aggtgtttcg caaacaactt gaccccttcc cacaccgccc tgtgcaaagc      360

catggcctgg attgcactga tatcaaggac acaatcggct cagtgaccaa gactccaagc      420

ggcctgtata taattcaccc agagggatcc tcatatcctt ttgaagtgat gtgtgatatg      480

gattacaggg gaggcgggag gactgtgatt caaaaacgca ttgacggtat cattgatttt      540

cagagattgt ggtgcgacta cctggacggg ttcggggacc ttctcggaga gttttggtta      600

ggcctgaaaa agattttcta tattgtgaac cagaagaata ctagcttcat gttgtacgta      660

gctttagagt cagaagatga taccctggct tatgcgtctt atgacaattt ctggttggag      720

gacgaaacga ggtttttcaa gatgcacttg ggccggtatt ctggaaatgc cggcgatgca      780

tttagaggtc tcaaaaaaga agataaccag aacgcaatgc ctttcagtac ttccgacgtc      840

gataacgacg ggtgcagacc agcctgtttg gtgaatgggc agtccgtaaa atcatgctcc      900

cacctgcaca acaagacagg ctggtggttt aacgagtgtg ggctcgccaa cctgaacggc      960

atacatcatt ttagcggcaa attgctggcc actggaatcc aatggggcac ttggaccaaa     1020

aacaattccc ccgtgaaaat caagtcagtt tccatgaaga tacgccgcat gtacaatccc     1080

tattttaag                                                             1089


<210>  4497
<211>  1350
<212>  DNA
<213>  Homo Sapiens

<400>  4497
cgagcaggcg ctcctcgctg cacctacacg tttgtgttac cgccccagaa attcacagga       60

gccgtgtgct ggagcgggcc cgcgagtact cgggccacac cagaagccgc caatgcttct      120

gaactcgccg ccttgaggat gcgagttggc cggcacgagg agctgctccg ggagctccag      180

aggttagccg ctgctgacgg tgccgtcgcc ggggaggtca gagccttacg aaaggagagc      240

cggggactga gcgctcggct gggacagttg agggcgcaac tccagcacga agctggccct      300

ggcgcagggc caggggctga cctcggagct gagcctgcgg cggcactggc tctgctgggc      360

gagcgagtgc tgaacgcttc tgctgaggcc cagcgggctg cagcacgctt ccatcagctg      420

gacgtcaaat tcagggaact ggcccagctc gtcactcagc agagcagcct gatcgcacgc      480

cttgagaggt tatgccctgg cggggctgga ggacaacagc aggtattacc tccgcctccg      540

cttgtccccg tcgtcccagt tcgtttggtt ggatccacct ccgacaccag ccggatgttg      600

gacccagcgc ctgaacctca gcgcgatcag acacagcgcc agcaagaacc aatggcgagc      660

ccgatgcccg cggggcaccc agctgtaccg actaaacccg tgggcccctg gcaggattgc      720

gccgaagctc gccaggcggg tcacgagcag agcggggtgt acgagctgcg cgtggggagg      780

catgtagtgt cagtatggtg cgagcaacag ctggagggag gcggctggac cgtgatccaa      840

agacgtcagg atggatctgt caactttttc accacatggc aacactataa agctgggttt      900

ggacgacccg atggcgaata ctggctggga ttagaacctg tctaccagtt gacctcacgc      960

ggcgaccatg agctgctggt actgctggaa gattggggag gtagaggcgc gagagcacac     1020

tatgacggtt ttagtttgga gcctgaatct gatcattacc ggttgagact gggacaatat     1080

catggggacg caggcgattc cctgagttgg cataacgata aaccattcag caccgtcgac     1140

agagatcgag actcttattc tggcaattgt gcactgtacc aacgcggcgg atggtggtac     1200

cacgcctgcg cccattctaa tctcaatggc gtttggcacc atggtggtca ctataggtcc     1260

cgctaccaag atggggtgta ctgggcagag tttagaggag gtgcctattc cttaaggaag     1320

gcggcaatgt tgatccggcc tctcaaactt                                      1350


<210>  4498
<211>  531
<212>  DNA
<213>  Homo Sapiens

<400>  4498
gccccaatgg gaggaccgga actggcccag catgaggagc tcacacttct ctttcacgga       60

acattgcagc tcggacaggc gcttaatggt gtgtacagaa ccacagaggg tcggctcacc      120

aaagctcgga attctctggg gctttacggg aggacgatcg aacttctcgg ccaggaagtc      180

tctcggggaa gagacgctgc ccaggaactg cgagccagtc ttctggaaac gcaaatggag      240

gaagacatcc tgcagttaca ggccgaagcg accgcagaag tgctcggaga agtggctcag      300

gcacagaaag tcctgaggga ttcagtgcag cggcttgagg tgcagctgag atcagcatgg      360

ctcggccccg catatcgtga attcgaggta ttgaaggcgc atgccgacaa gcagtcccac      420

atcctgtggg cactcaccgg ccacgtgcaa aggcagcgac gcgaaatggt ggctcagcag      480

cataggctgc gacaaatcca ggagcgtttg cacacagccg ccctgccagc g               531


<210>  4499
<211>  1014
<212>  DNA
<213>  Homo Sapiens

<400>  4499
agcacagtcc acgagattct ttgtaagctc agcctggaag gtgatcatag tacaccgcca       60

tctgcttacg gatccgttaa ggcctacaca aactttgatg cagaacgcga cgctttgaat      120

attgaaaccg caattaaaac taagggtgtc gatgaagtta ccatcgttaa tattgtgacg      180

aatagggaca atgcccagcg gcaggacatt gtcttcagtt accaacggcg caccaaaaag      240

gagctcgctt ccgcgctgaa gagcgccctg tccggacatt tagaaaccgt catccttggc      300

ctccttaaga cgcccgctca gtacgatgca agcgagctga aggccagcat gaagggcttg      360

gggaccgacg aggacagctt aattgaaatt atctgctcac gcactaacca ggagttgcag      420

gagataaatc gcgtgtacaa agagatgtat aagaccgatc tggagaaaga cataattagc      480

gacacctccg gggattttag aaaattaatg gtagccttgg ctaagggtcg gcgcgccgaa      540

gacggcagtg taatcgatta tgagcttatt gaccaggatg cgcaagacct gtatgacgcg      600

ggggtgaaac gcaagggaac agacgtgcct aaatggatca gcatcatgac tgagagatct      660

gtaccccatc tgcaaaaggt cttcgatcgc tataaaagct actctcctta cgatatgtta      720

gaatcaatta ggaaggaggt gaagggggat ttagagaatg cctttctcaa cctggtccag      780

agaatccaga ataaacctct gtatttcgca gaccaacttt acgattcaat gaaaggaaag      840

ggtacccggg ataaggtact gatacgtata atggtttcca gaagcgaagt cgacatgttg      900

aaaatccgct ccgaatttaa gcgtaagtac gggaagtcac tgtattatta catccagcag      960

gacactaagg gcgattatca gaaggctctt ctgtacctgt gtggggggga cgat           1014


<210>  4500
<211>  1623
<212>  DNA
<213>  Homo Sapiens

<400>  4500
ttgtctaatg gccacacttg cgtgggatgc gtgctggtcg tatccgtaat tgagcagctg       60

gcacaggtgc acaactccac tgtccaggct agtatggagc ggctgtgcag ttatctgcct      120

gagaagctct ttcttaagac gacctgctac ctggtgattg ataaattcgg cagcgacatc      180

attaaattgt tgagcgctga catgaacgcc gatgtagtct gtcacaccct ggagttttgc      240

aaacagaata ctgggcaacc actgtgccac ctgtaccccc tgccaaaaga gacctggaag      300

tttaccctgc agaaagcccg ccagattgtg aagaaaagcc ctattctgaa atacagtcgc      360

tctggatctg atatatgcag ccttcctgtc ctggccaaaa tatgtcagaa gatcaagctg      420

gctatggaac agtccgtgcc cttcaaagat gtggattcag ataagtatag tgttttcccc      480

accctcaggg gctaccactg gcgagggaga gattgtaatg acagcgacga gtctgtatat      540

cccgggcgcc gacccaataa ttgggacgtc caccaggatt ccaattgcaa cggaatttgg      600

ggagtggacc ccaaagatgg agttccctac gaaaaaaagt tctgtgaggg gagccagccg      660

cgggggatta ttttgttggg cgacagtgca ggtgcccact tccatatctc acctgagtgg      720

atcacagcat ctcagatgtc ccttaattca ttcatcaacc tgcccacggc gttgactaac      780

gaactcgact ggcctcagtt atctggtgcc acaggcttcc tggattcaac cgttggcatt      840

aaagagaaaa gtatatactt gagactgtgg aaaaggaacc actgtaacca tcgggactat      900

cagaacattt cccgaaatgg agcatccagc cggaacctga agaaattcat cgaaagcctg      960

tcccggaaca aggttcttga ttatcccgct atagtcatct atgccatgat cggcaatgac     1020

gtttgtagcg gcaaaagtga ccccgtccca gctatgacaa caccagaaaa gttatatagc     1080

aacgtgatgc agacactgaa gcacctgaac tcccacttgc ctaacggctc ccacgttatc     1140

ctttacggtc ttcctgacgg cactttcctg tgggacaacc tccacaatcg gtatcaccca     1200

ttagggcagc tgaacaaaga tatgacctac gctcagctct acagttttct gaattgtctc     1260

caggtcagtc cctgccatgg ttggatgagc tctaataaga cactgagaac actgacatcc     1320

gaacgcgctg aacagctttc caatactctt aagaagattg ctgcttccga gaagtttacc     1380

aatttcaatc tgttttatat ggattttgcc tttcacgaaa taatacagga gtggcagaaa     1440

agaggcggac aaccttggca gctcattgag ccagtggatg gctttcatcc taatgaggtg     1500

gccctcctcc tcctcgctga ccacttctgg aagaaggtgc agttgcagtg gcctcagatt     1560

ttgggcaaag aaaacccctt caatccacag atcaaacagg tgtttggtga ccaggggggg     1620

cat                                                                   1623


<210>  4501
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  4501
gaggccggag gatcctgcct caggtgggaa ccccactgcc agcaaccgct gcctgatcgt       60

gttccaagca ccgccatcct gccccctagg ctgaacgggc cctggatatc cactggatgt      120

gaggttaggc cgggtccgga attcctgact agagcttata ccttttaccc tagcaggctg      180

tttcgcgcgc atcagtttta ctacgaggac cccttttgcg gcgagccagc gcacagtctc      240

ctcgtaaaag gtaaggtccg gttgcggcgc gcttcttggg tgactcgggg ggctacagag      300

gccgactacc acttgcataa agtggggatc gtgttccata gcagacgggc cctggtggac      360

gtgaccggcc gtctgaatca aaccagggca gggcgggact gcgcgcggag gttgccacca      420

gcccgggctt ggttacccgg ggccctgtac gagttgagga gcgcacgagc tcagggagac      480

tgcttggagg ctctgggcct taccatgcac gagctgtccc tcgtgcgagt gcagcggcga      540

ctgcagccgc aaccaagagc ctcaccgaga ctggtggagg agttatacct gggggatatc      600

cacacggatc ctgcagaaag gcgccattac agacccacag ggtaccagcg accactgcaa      660

tctgcgttgc atcatgttca gccatgtcca gcatgcggcc tgatcgctag gagcgacgta      720

catcaccctc ctgtcctgcc tccaccgttg gccttgcctt tacatttggg cgggtggtgg      780

gtaagcagcg gctgtgaggt gaggccagct gtgctcttcc ttacacggtt atttactttc      840

catggtcaca gtcgcagctg ggaaggctat taccatcatt ttagcgatcc agcatgcagg      900

caacccacgt ttaccgtcta cgcggctggc cgctatactc gggggacacc gtcaacaagg      960

gtgcgtggag ggaccgaact ggtgtttgaa gtgactagag cccacgtaac ccccatggac     1020

caggtcacca ctgcaatgct gaacttttct gagccttcca gttgcggtgg agcgggcgct     1080

tggtccatgg ggacagaaag agatgtcacc gctaccaacg gatgcctgcc ccttggcatc     1140

cggctccctc acgtggaata cgaattattt aaaatggagc aggatcctct ggggcagagc     1200

ttattgttta taggacagag acctacagac gggagttcac ccgatacccc tgagaaaagg     1260

cccaccagtt accaggcacc tctggtcctg tgccatgggg aagcccccga tttctctaga     1320

ccgccccaac accggccttc ccttcagaag catccgtcta ccggtggg                  1368


<210>  4502
<211>  1128
<212>  DNA
<213>  Homo Sapiens

<400>  4502
gaagtgtcag cagatcaagt ggccacggta atgtgggact attttagcca gctgagcaac       60

aatgccaagg aggcagtgga acatttgcag aagtccgaac tgacccagca gttgaacgca      120

cttttccagg acaagctcgg ggaagtgaat acctacgctg gggacctgca aaagaagctt      180

gtgccatttg ccaccgaact gcatgaaagg ctggccaaag actcagagaa gctcaaggaa      240

gaaatcggga aagagctgga ggagctgcga gcaaggctgt tgcctcatgc caacgaagtg      300

tcccagaaga ttggagacaa cctgagagag ctccagcaaa gactcgagcc atacgccgac      360

cagttaagga cgcaagtcaa cacgcaagct gagcagctga gaagacagct cacgccttac      420

gcccagcgta tggaacgcgt cctgagggaa aatgcagact ctttacaggc gagtttgaga      480

ccgcatgccg acgagctgaa agccaagatt gatcagaatg tcgaggaact taaaggaagg      540

ctgactccct acgctgacga gtttaaagta aagattgatc agacagtcga ggagctgcgc      600

cgtagcttgg ccccatacgc tcaggacact caagaaaaac tgaaccatca gttagaagga      660

cttactttcc agatgaagaa gaacgcagaa gagctgaaag ctcgaatctc agccagtgct      720

gaggaactta gacagaggtt agctccactg gctgaggacg taagaggcaa tctgaggggt      780

aataccgagg gcctgcagaa atccctggca gagctgggag gacatttgga ccagcaggtc      840

gaagagtttc gcagaagagt tgaaccatac ggtgaaaatt ttaataaggc actggtccag      900

cagatggaac agctgcgcca aaagctcgga cctcacgctg gagatgtgga aggccacttg      960

agctttctgg agaaggactt gagggacaaa gtgaactcat ttttctccac cttcaaggag     1020

aaggaatcac aggacaaaac tctgtccctc ccagaattag aacagcagca agaacagcaa     1080

caggaacaac agcaagaaca ggtgcagatg ctggcgcccc tggaatcc                  1128


<210>  4503
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  4503
agcggcgccg gcgcatctcg gccaccccac cttgtgtttt tactggcaga cgacctcgga       60

tggaacgatg ttgggtttca tggtagccgg atcagaacgc ctcacctcga tgctttggcc      120

gcaggaggag tgctgctgga taattactac acccaacccc tgtgtacccc ttcacggagt      180

cagcttctga ctggtcggta tcagataagg acggggctgc agcaccagat tatttggcct      240

tgccagccat cttgcgttcc actcgacgag aaactgctgc cccagcttct gaaggaagct      300

ggctacacca cccacatggt tggaaagtgg catctcggca tgtaccgtaa agagtgcctc      360

cctacacgca gaggattcga cacttacttt ggttacttac ttggcagtga agactactac      420

agtcatgaac gctgcactct catagatgct ctgaatgtga cccgatgtgc tcttgacttc      480

cgggacgggg aggaggtcgc caccggctac aaaaatatgt actccaccaa tattttcaca      540

aaacgggcga ttgccctcat caccaaccac ccccccgaga agcctctgtt tctctatctg      600

gccttgcaat ctgtgcatga gcccctccag gtgcccgagg agtacttaaa gccgtatgac      660

ttcattcaag acaaaaatcg gcaccattat gccggcatgg taagtctcat ggacgaagcc      720

gtagggaacg tgaccgctgc cctcaagtcc tccggactgt ggaacaacac cgtgttcatc      780

ttcagcacag acaacggggg tcagaccttg gccggtggca acaactggcc acttcggggg      840

agaaagtggt cattgtggga gggaggcgtc aggggggttg gctttgtcgc atcccccctc      900

ctcaagcaga agggcgtgaa gaaccgggaa ctgattcaca tctccgactg gcttccaaca      960

ttggttaagc tggctcgggg tcatacaaac ggcaccaaac ctctggatgg gttcgacgtc     1020

tggaaaacga tctcagaagg tagcccaagt cctagaatag agctgctgca caacatcgat     1080

ccaaatttcg tggactccag tccctgcccc agaaactcaa tggcccccgc gaaggacgac     1140

agttccttgc ccgagtatag cgctttcaat acaagtgtcc atgccgcaat acgccacggc     1200

aattggaagc ttctgaccgg gtatccgggc tgtggatatt ggttcccacc ccctagtcaa     1260

tataatgtca gcgagatccc cagtagcgac cctcctacta aaaccctgtg gctcttcgac     1320

attgaccgcg acccagagga gagacatgac ctgtctcgcg agtatccgca tatcgtgacc     1380

aaactcctta gcagactgca attttaccac aaacattctg tgccggtgta ctttccagcc     1440

caggatccca gatgtgatcc taaggcgacc ggcgtctggg gaccgtggat g              1491


<210>  4504
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  4504
gccgggggcc ctggtagcag ggcacgggca gcaggggccc gaggatgcag gcttcggtcc       60

cagctcgtcc ctgtcagggc cttaggattg ggccaccgct cagatgagct ggtacggttc      120

aggttctgta gtgggagctg tagaagggcg aggagccccc atgatctttc tcttgcctca      180

ctcctggggg ctggtgccct gagaccacct ccgggctcca gacctgtttc tcagccttgt      240

tgtaggccaa ctaggtacga ggcagtctcc ttcatggacg tgaactcaac ctggaggaca      300

gtggacagac tgtctgccac cgcttgtggg tgcttaggg                             339


<210>  4505
<211>  1107
<212>  DNA
<213>  Homo Sapiens

<400>  4505
gagtctagtg aacgtgtatc ttattacttt agctatcagc atgtaacgaa ggttgatgaa       60

gtggtggccc aatctctggt gttccctgca gtgactctgt gtaacctcaa cgggttccgc      120

ttctcaaggc ttaccactaa tgacctgtat catgccggag agctcttggc tctgctcgat      180

gttaatctgc agatccccga tccacatctg gcagaccctt ccgtccttga ggcactccga      240

caaaaggcca actttaaaca ttacaaacca aagcagttct caatgttgga gttccttcac      300

cgtgtaggcc atgacctgaa ggatatgatg ctctactgca aatttaaggg acaggagtgc      360

ggacaccagg acttcacaac cgtctttacg aagtacggta agtgctacat gttcaacagc      420

ggagaggatg gaaaaccact gcttacaaca gtgaagggcg gtaccggaaa tgggctcgaa      480

attatgctgg acatccagca ggacgaatac ctgcccatct ggggggagac tgaagagaca      540

actttcgaag cgggcgtcaa ggtgcagatc catagccagt ctgaaccgcc ttttattcag      600

gaattaggtt ttggagtagc cccagggttc caaaccttcg tcgccaccca ggagcagcgg      660

ctgacatatc tccctccacc ttggggtgag tgcaggtcct cagagatggg cctggatttt      720

ttccctgtgt actctatcac tgcgtgtcgt atcgactgcg agacacgtta catcgtggag      780

aactgtaact gccggatggt ccacatgcca ggcgatgccc cattttgtac ccctgaacaa      840

cacaaagaat gtgcagagcc agccctgggg ctcctcgcag aaaaagattc aaattattgc      900

ctgtgccgta ctccttgcaa tctcactagg tataacaaag aattatctat ggtcaaaata      960

ccaagcaaga ccagcgccaa atacctggag aaaaagttca ataagagcga gaagtatatt     1020

tccgagaaca tattagtgct ggatatcttt ttcgaagctc tgaattatga gacgatcgag     1080

caaaagaagg cttacgaggt cgctgcc                                         1107


<210>  4506
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  4506
aggctcatga aggaagagag ccccgtcgtc agctggcgac tggagcccga ggatgggacc       60

gcccttgacg tgcatttcgt aagtactctg gagcctctga gtaacgcagt gaagcgtaac      120

gtcccaaggt gcatcatcat tctcgtgctg caggaaccca ccgcttttcg catctccgta      180

acttcatctt gcttcgttca gaataccctg acaaagttgc tgaaggatcg aagaaagatg      240

cagactgtac agtgcgccac tgctcgtgaa actagc                                276


<210>  4507
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  4507
cggctgatga aggaagagtc tcccgtcgtg tcatggcggc tggaaccgga agacggaaca       60

gctctggacg ttcattttgt gagcactctc gagccgctct ctaacgccgt taagaggaac      120

gtccctcgat gcattatcat cctcgtcctg caggagccca ccccattccg tatttcagta      180

accagttctt gtttcgtgca aaacacactc accaagctgt taaaggaccg gaggaagatg      240

caaacagtac agtgcgcaac agctcaggag accagc                                276


<210>  4508
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4508
catagtgacc cggcgcgtcg gggagaactg agcgtgtgcg acagcatcag tgaatgggtc       60

accgctgccg ataaaaagac cgcagtagat atgagcgggg gaactgtgac cgttttggaa      120

aaggtgcctg tgagtaaggg ccagctgaaa cagtactttt atgagacaaa gtgcaaccct      180

atgggatata ccaaggaggg gtgtcgtgga attgataagc ggcattggaa ctcccagtgt      240

cggacgaccc agagctacgt ccgcgcgctc acaatggaca gtaagaagcg aatcgggtgg      300

agatttattc gaatcgatac gtcttgtgtc tgtacactga ccatcaaacg gggccgg         357


<210>  4509
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  4509
tccgcctcaa gtcggagacg gcaacaaagc cgaaaccgca gcacgcagag ccaggatgtc       60

gcccgcgtct ccagtgcttc agactataac tctagcgaac ttaagacagc gtgtcggaag      120

catgaactct acgtatcatt ccaggacctc gggtggcaag attggataat agcgcctaag      180

ggatatgctg ccaactactg cgacggagag tgcagtttcc ctctgaacgc ccacatgaac      240

gcaactaacc atgccatcgt gcagacactg gtgcatctca tgaacccaga atacgtgcca      300

aagccctgtt gtgctcctac taaactgaac gccatttccg tactgtactt tgacgacaat      360

tccaatgtca ttttaaagaa atatcggaat atggtggtga gagcatgcgg gtgccac         417


<210>  4510
<211>  699
<212>  DNA
<213>  Homo Sapiens

<400>  4510
cataaacagc catggcctgg gctggcacaa gcacataggg ataacaaatc cactctggcc       60

cgcataatcg ctcaggggct gatcaagcac aatgcagagt cccggataca gaacattcat      120

ttcggcgata ggctgaacgc ttccgctcag gtggcgcctg gcctggtagg atggctgatc      180

agcggaagga agcatcagca gcagcaggag agttctataa atatcacaaa tattcagctg      240

gactgtggcg gcatccagat ttcctttcac aaagagtggt ttagtgcgaa catttctctc      300

gaatttgacc tggagttgcg accatctttc gacaataaca tcgtaaaaat gtgtgctcac      360

atgagcatcg tcgtggaatt ttggctggag aaggacgagt ttggaaggcg tgatttagtc      420

atcggcaagt gcgatgctga gccaagctct gtgcatgtcg cgatccttac agaggccatt      480

ccgcccaaaa tgaatcagtt tctctacaac ctcaaggaaa acctgcagaa ggtgctcccc      540

cacatggtgg aaagccaggt gtgtcccctt atcggcgaga tcctgggcca gctggacgtg      600

aaattgttga agagccttat cgaacaagaa gcggctcatg aacccacaca tcatgagaca      660

agccagccga gcgcttgcca ggctggtgaa tccccttcc                             699


<210>  4511
<211>  477
<212>  DNA
<213>  Homo Sapiens

<400>  4511
caggaggtgc ttgctggtgt gtcatctcag ttgctgaacg acctgaccca gggcctctta       60

agggcagact ttttgccttc ccttcagacc actggcctgc aaaaaccact ttctagcgcc      120

ttcgacggcg tgtccggact gctggatatc tttggcccac cgctcaccaa tgaaattaat      180

accgtaagca ttcaggtaaa gaaccctcag ttacttcacg tatccattga gagtacccca      240

cagcgcaagg aggccacagt acaagtgccg tttactagcg agcttatcgt tcagcttctt      300

accatgaagc catttacggc taacatgcag agtgatatca aagtgcagat ccgtctggag      360

aaaaacgtgg ggggccgcta tgagctggca ttcggtaact gcaggctcct tcccgaagct      420

atttggattc agactggggt tcaactggca ccagcacaga atctcctttg gcagact         477


<210>  4512
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  4512
caaacgatct acccaggcat taaagctaga attacacagc gggccttaga ttatggtgta       60

caggccggga tgaagatgat tgagcagatg ctgaaggaaa agaagctgcc agacctcagt      120

gggagtgagt cactcgagtt cctcaaggtt gattacgtca actataattt cagcaatata      180

aaaatttccg ctttttcttt ccccaatacc tctttagcct ttgtgcctgg cgttggcatc      240

aaagcgctca ccaaccatgg cactgctaat atctcaacag attggggttt cgagtcacca      300

ctcttccagg acacgggagg agcggactta ttcctgtctg gtgtctactt caccggcatc      360

attatcctga ccaggaatga tttcggccat ccaaccctga agctgcaaga ttgctacgcc      420

caactgtcac acgctcacgt gtctttttct ggggagctct cagttctcta taattctttc      480

gctgagccca tggagaagcc catcttaaaa aatctgaatg agatgctttg tcctattatt      540

gcatctgaag tgaaggcgct gaacgccaat ctgtccacgc ttgaggtcct taccaaaatt      600

gacaattaca ccctgctcga ttatagtctg atttcctcac ccgagataac agaaaactac      660

ctggatctga atcttaaagg ggtcttctat cctctggaga acctgacgga ccctccgttt      720

tcccctgtcc ctttcgtgct gccggagaga agtaactcaa tgctgtatat tggtatagct      780

gaatattttt ttaagtctgc cagtttcgcc cacttcactg ccggggtctt caatgttacg      840

cttagcaccg aggagattag caatcatttc gtacaaaaca gtcaggggct cggaaatgta      900

ctgtcaagaa tagcggagat atatattctt tctcagccat tcatggtgcg cattatggct      960

accgagccac ccattattaa cctccaaccc gggaacttca cacttgatat ccccgcaagt     1020

atcatgatgt taacgcagcc caagaactca accgtcgaaa caatcgtctc aatggacttc     1080

gtggcttcta caagcgtagg gctggtcatc ttgggccagc gtctcgtgtg cagcctttct     1140

ctgaataggt tccgattggc cttgccagag tcaaatcgta gcaacataga ggtcctccgg     1200

tttgaaaata tattgtcctc catccttcac tttggtgtgc tccccctcgc gaatgcaaaa     1260

ctccagcagg ggtttccact gtcaaatcct cacaagtttc tttttgttaa cagtgacatc     1320

gaggtgctgg agggatttct tttgattagt accgatctta aatatgaaac aagttcaaaa     1380

cagcaaccct cctttcacgt ttgggaggga ctgaacctta tttcccggca atggcgcggt     1440

aaatccgcac cc                                                         1452


<210>  4513
<211>  1350
<212>  DNA
<213>  Homo Sapiens

<400>  4513
gcccagaggg cagatgtggg gggcgaagcc gccggcacaa gcattaatca tagccaggca       60

gtcctgcaga gactgcagga attactgaga cagggcaacg cctcagatgt ggttttgcgt      120

gtgcaggccg caggaaccga cgaggtgcgc gtcttccatg cccatcgctt acttctcggc      180

ctgcattccg aactgtttct cgagctgctt tccaaccagt ctgaggctgt gttgcaggag      240

cctcaagact gcgctgccgt gttcgataag ttcataagat acctgtattg cggtgagctg      300

accgtgctgc tgacccaggc aatcccgttg cacaggttag ctacgaaata cggagtcagc      360

agcctccagc gcggcgtggc cgattatatg cgcgcccatc ttgcgggcgg ggccgggccc      420

gcagtgggct ggtaccacta cgctgtggga acaggggatg aggccctccg tgaatcctgt      480

ctgcagttcc tcgcttggaa tctgagtgcc gtcgccgctt ctactgagtg gggcgcagtc      540

tcacccgagc ttctctggca gctcctgcag cgcagcgatt tggtcttgca agacgagtta      600

gaattattcc acgcgcttga ggcctggctg ggacgtgcta ggcctccacc agcagttgcc      660

gagagagccc tgcgggccat aaggtaccca atgatccccc cagcccaatt attccaactg      720

caggccagga gcgcggccct ggcccgacac ggtccagccg tcgctgactt gctcctccag      780

gcctaccaat tccacgctgc ttcaccattg cactacgcga agttcttcga tgtgaatgga      840

agtgccttcc ttccacggaa ttacctggcc cccgcgtggg gcgccccgtg ggtgattaac      900

aaccccgcaa gagatgacag atccacttcc ttccagactc agctgggccc aagcgggcat      960

gacgctggaa ggagagtcac atggaacgtc ctgttctcac cacgctggct ccctgtttcc     1020

cttcgccccg tatatgctga tgcagccggg actgctcttc ctgccgccag accagaggac     1080

ggtcgaccac ggttggttgt caccccggcc tcttccgggg gggacgcagc tggggttagt     1140

tttcagaaaa cggtccttgt aggcgcaaga cagcagggac gcctgctggt gcgccacgcc     1200

tacagtttcc atcagtcaag cgaggaagct ggtgattttc tggcacacgc tgacctccag     1260

agacgaaatt cagagtacct cgtggagaac gccctgcacc tgcacctcat agtgaaacca     1320

gtgtaccata ctttgattcg cacacctaaa                                      1350


<210>  4514
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  4514
ggagttactg gcgcttggcc taccagcggt cttagcatcc tggctcagct gcaacccagt       60

tgcgagctga ggtggaccca actttcccgg agcagctggc gcgacctggt gatgacaacg      120

agcctgtggt cattagcata ctttcagcat ttttctcaag agaccaccac ccaagagcag      180

cttgacgaaa tggaagaaat ccctcgcgaa tcacagtgcg gtaggcagga ttttcatgca      240

ctgagctgtc ctacagccag cccccgggac agggtgctgt tgtgctgccc gggctggaga      300

gctatggtgc cttct                                                       315


<210>  4515
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  4515
cagccgctcc ggtcacaacg gagcgttcct gaagctttca gcgccccctt agaactgtct       60

cagcctctga gcgggctcgt ggatgactac ggcattctgc ctaaacatcc gcggccgcgg      120

ggaccgcggc cactgctcag ccgagcccaa caaaggaagc gtgacggacc ggacctggct      180

gagtattatt acgatgccca tttg                                             204


<210>  4516
<211>  1563
<212>  DNA
<213>  Homo Sapiens

<400>  4516
cgatgttgct gttgcgcatg caaatcagag acaaatgggg gcaataccgg aagccaggga       60

ggaaatcctc ctcccagcac ccctattaca gtgacaggtc acgggctggc ggttcagtcc      120

agtgaacagc tgttgcatgt gatataccag cgggtcgaca aagccgttgg gctggccgag      180

gctgcgcttg gcctggccag ggccaacaat gagctgttaa agcggttgca ggaagaggtt      240

ggcgacttga ggcagggaaa ggttagcatt cccgatgagg atggcgagtc tagagcccac      300

tcctctcctc ccgaagaacc gggccctttg aaggagagcc ccggggaagc atttaaagca      360

ctctccgcgg ttgaagaaga gtgcgatagc gtcggtagcg gagtgcaggt tgttattgag      420

gaactccggc aacttggggc ggcctccgtt ggtcctggcc ctctgggatt cccagcaacc      480

cagagggaca tgcggttacc ggggtgtacc ctggccgcct ctgaagctgc tccactgctg      540

aatcctttgg tggatgacta cgtggcctct gaaggcgctg tgcagcgtgt gctcgttccc      600

gcttacgcga aacagttaag tccagcaact cagctggcta tccaacgcgc aactccagag      660

acaggacccg agaatgggac taaactcccc ccacctaggc ccgaggacat gttgaatgcc      720

gccgccgccc ttgactccgc tcttgaggag tctggcccag gtagcacagg ggaacttcgg      780

cacagtctgg gcctgaccgt ctccccgtgt cgtactcggg gcagtggaca aaaaaacagc      840

cgtcggaaac gcgacctggt gctctctaag ctggtccaca atgtccataa tcacattact      900

aacgataaaa ggtttaatgg gtcagagtca atcaagtcca gctggaacat tagcgtcgtg      960

aaatttttgc ttgaaaaact gaaacaggaa ctggtcacat ccccgcataa ctacactgat     1020

aaggaactga agggcgcgtg cgtcgcttat tttttaacca agcgccgtga gtatagaaac     1080

agtttgaatc ctttcaaggg tctcaaagag aaggaagaga agaaattgcg cagccgcaga     1140

tatagactct tcgccaaccg gtcatctatt atgcgtcatt ttggtcccga agatcaaagg     1200

ctttggaacg acgtgactga ggagctgatg tccgacgagg aggattccct gaacgaacct     1260

ggtgtgtggg tcgctcgccc ccccagattt agagctcagc gtctgaccga gttgtgttac     1320

cacttggacg ccaactctaa acacggcaca aaggctaaca gagtctatgg gcctccctcc     1380

gacaggttgc ctagcgctga agcacaatta ctcccccccg agttatataa cccgaacttc     1440

caggaggaag aggatgaggg cggcgacgaa aatgcaccgg gctcccctag ctttgaccag     1500

ccgcataaga cttgttgccc tgatctgaat agctttatcg agatcaaggt tgaaaaggat     1560

gaa                                                                   1563


<210>  4517
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  4517
agacccaaac caagcgcttc tgaagtcctc actcgccacc tcctccagcg gcggttgcct       60

cattggacct ctttttgcgt tccttactcc gccgtgcgta acgatcaatt cggcttgtcc      120

cattttaatt ggccagtaca gggagcaaat tatcacgtgt tacggaccgg gtgttttcct      180

ttcataaagt accactgcag caaggcaccc tggcaggatc ttgctaggca gaatcggttc      240

tttaccgccc tgaaggttgt taacctgggc ataccaaccc tcctttacgg ccttggatca      300

tggctgtttg ctagagtgac ggagaccgtc catacttctt acggccccat caccgtgtat      360

tttctcaata aggaggacga gggagcaatg tac                                   393


<210>  4518
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  4518
aaatctatgg agaacacagt tacaaggaat tctaccgccg tcataaatac ccaggccgag       60

ggaacccttt caccccccgg gttaagttca ctgccagtag tgagggagtg ggctctgaca      120

cacaccgcac agctcccgga atgctgtgtg gatgttgtgg gggtgaatgc ctcttgcccc      180

ggcgcatctc tgtgcggtcc cggttgctat cgccgatgga acgcagacgg ctccgcctcc      240

tgcgtccgct gcgggaatgg cacattgcca gcctacaacg gctcagaatg ccggagtttt      300

gctgggcctg gtgctccttt cccaatgaat cgttcaagcg gtaccccagg cagaccacat      360

cctggggccc cccgcgtggc tgcttcc                                          387


<210>  4519
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  4519
gaagacctgt gccgcgctcc tgatgggaag aagggggagg cgggaagacc cggtaggcgg       60

ggccgaccag ggctgaaggg ggagcagggt gaacctggcg cacctggaat tcgtacgggc      120

attcagggac tgaagggaga ccagggtgaa ccgggcccga gtggaaatcc aggaaaagtt      180

ggataccctg gccccagcgg tccactgggc gccaggggaa ttccggggat taaaggcaca      240

aagggctcac ccggtaacat caaggatcaa ccacgacctg ccttctccgc catccgcaga      300

aatcctccga tgggcggcaa tgtggtgatt tttgatacag ttataacaaa tcaggaggag      360

ccataccaaa accattcagg ccggttcgtg tgcaccgtcc ctggttacta ttactttaca      420

ttccaggtgc tcagccagtg ggagatatgt ctcagcatcg tttccagctc cagagggcag      480

gtccggcgaa gtctggggtt ttgcgacacc acaaacaaag ggttgtttca ggtcgtttct      540

ggcggcatgg tgcttcaact gcaacagggg gaccaggtgt gggtggagaa agatccaaag      600

aagggacata tttaccaggg ctcagaggct gacagtgtat tcagtggttt tctgatattt      660

ccctcagcc                                                              669


<210>  4520
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  4520
cagctgagct gtaccggccc ccccgctatt ccagggatac ccggcattcc aggcacgcca       60

ggacccgacg ggcaaccagg gacacccggc atcaagggcg agaaaggtct gccaggtctg      120

gcgggcgatc acggtgaatt tggcgagaaa ggcgaccccg gcatacccgg aaaccccggc      180

aaagtgggtc ctaagggtcc gatgggtccc aaggggggcc ctggggctcc cggtgcccca      240

gggccaaaag gcgaaagcgg ggattacaag gctacccaga agatagcatt ctctgccacg      300

cggacaatca atgtgccctt gaggagagat cagacaatcc gcttcgatca cgtgattacc      360

aatatgaaca acaattacga gccaaggtcc ggaaaattta cctgcaaggt tcctggtctc      420

tattatttta cttaccatgc ttcttctaga ggtaacctgt gcgtaaatct catgcgcggt      480

agagaacgcg cgcaaaaagt tgtcactttc tgtgactacg cctataacac cttccaggtg      540

acaactgggg ggatggtgct gaagttggaa cagggggaga atgtctttct gcaggctaca      600

gacaagaatt cattactggg aatggaaggg gccaactcta tcttcagtgg ctttctgctg      660

tttcctgata tggaagcg                                                    678


<210>  4521
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  4521
aatacagggt gctacggaat ccccggaatg cctggtctgc caggtgcgcc tggtaaagat       60

ggctatgacg ggctgccagg acctaagggc gaacccggaa tcccggctat ccctggtatt      120

cgaggcccca agggccagaa aggagagcct gggcttcctg ggcacccagg aaaaaacggt      180

cccatggggc ctccaggcat gcccggtgta cccgggccaa tgggcattcc cggcgaaccg      240

ggagaggagg gcagatacaa gcagaagttc cagtctgtct ttactgtcac tcggcaaacc      300

catcaacccc cggctcctaa ctctctgatc aggttcaatg cagtgttgac taatccacag      360

ggagactacg acacctcaac cggcaagttt acttgcaagg tgccgggact gtactatttc      420

gtctatcatg cctctcatac cgctaatctt tgcgtgctgt tatacagatc tggagtgaaa      480

gtggtgactt tctgtggaca cacctctaag acaaatcagg tcaatagcgg aggcgtgctt      540

ctccgactgc aggtggggga ggaggtctgg ctcgccgtga acgattatta cgatatggtc      600

ggaatccaag gatctgattc agtcttctct ggtttcctcc tgtttcccga t               651


<210>  4522
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4522
cactatgaga tgctgggtac atgtaggatg gtgtgtgacc catacggcgg caccaaggcc       60

ccttccacgg ccgcgacacc cgacaggggt ctcatgcaat cactgcctac gttcatacag      120

ggacctaaag gtgaggctgg gcgccctggt aaggcaggtc ctcggggccc tccaggcgaa      180

ccaggacccc ctggcccgat gggcccacct ggggagaagg gcgaaccagg gcggcagggt      240

ctgcctgggc ctcccggagc ccctggcttg aacgctgcag gcgccattag cgccgccacg      300

tatagcacag tgccaaagat tgcattctat gccgggttga agcggcaaca cgagggctat      360

gaagttctga aattcgacga cgtcgtcacc aaccttggca accattacga tccaactacc      420

gggaagttca cttgtagcat tcccgggatt tatttcttta cctaccacgt tctgatgaga      480

ggaggagatg gaaccagcat gtgggccgac ctgtgtaaga acaaccaggt gagggccagt      540

gccatcgccc aggatgccga ccagaactat gactacgctt ctaactccgt tgtgctgcat      600

cttgaacctg gcgacgaggt ttatattaag ctggatggtg gcaaggccca cggagggaac      660

aataataagt acagcacttt ttcagggttc attatctacg cggat                      705


<210>  4523
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  4523
gggggcgtcg gcgcgcggag agaagctcaa aggacccagc agcccgggca gcgagccgat       60

ccgcccaatg ccacagcgtc cgcatcctca cgcgagggac tgccagaagc ccccaagccc      120

tctcaggcct caggccctga gttctcagat gctcacatga cctggttgaa tttcgtgagg      180

aggccagacg atggggcgtt gcgcaaacgc tgcggtagca gggataaaaa gccaagggat      240

ttattcggcc cacccggccc accaggcgct gaagtcacag ccgaaacctt gcttcatgag      300

tttcaggaat tgctgaaaga ggcaacagaa cgccggttct caggactcct ggacccattg      360

ctgcctcagg gcgctggcct gcggctggtg ggggaggcct tccactgtag gctccagggc      420

ccacgaagag tcgataaacg cacgctggtg gagctccatg gatttcaagc tcctgccgcc      480

cagggtgctt tccttagagg tagcgggctg agccttgcca gcggtcggtt taccgcacca      540

gtgtccggaa tttttcagtt ctcagcttca cttcacgtgg atcacagcga actgcaaggc      600

aaggctaggc tgcgcgctcg cgacgtggtg tgcgtcctga tctgtattga gtccttatgc      660

caacggcata cctgccttga ggcagttagt gggctggagt ccaacagccg cgtgtttaca      720

cttcaggtcc aggggctgct gcaattgcag gccgggcagt acgccagtgt gttcgtcgat      780

aatggatctg gagcggttct gacaattcag gcaggctctt cattctcagg attattgttg      840

ggtacg                                                                 846


<210>  4524
<211>  600
<212>  DNA
<213>  Homo Sapiens

<400>  4524
ctgaattgct tcaccaaggg gcaaaagaac agcacactca tctttacgag ggagaatacg       60

atccgcaatt gtagttgtag cgcagacatt agggactgtg attactcctt ggcaaacctt      120

atgtgcaatt gtaagactgt gctccctctg gccgtcgaga ggacaagtta caatggtcat      180

ctcaccatct ggttcactga cactagcgcc ctgggccact tattaaattt taccttggta      240

caggacctga agctgagttt gtgttccacc aatactctgc caacggaata ccttgcaatc      300

tgtggactga aaagattgag aataaacatg gaggctaaac acccatttcc agaacagagc      360

ctgctcatcc actccggagg cgactctgac agcagagaga agcctatgtg gctccacaag      420

ggatggcagc cctgcatgta catttctttt ctggatatgg ctctgttcaa tagagacagc      480

gcgttcaaaa gctactccat tgaaaacgtc acatctatag ccaacaactt cccagatttc      540

tcctacttta ggactttccc catgccctcc aacaagtcct acgtcgtcac ctttatatat      600


<210>  4525
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  4525
cccgaatggg aacccgtgca aggcctgtta tcacagaacc acagctgtcg agacccacag       60

tgctgcggca acctgttggt gctctgcttg ttcctggtgt ggcaagtgcg gcactgttgg      120

caccaggtga ctaggacaag gttttccaca agaaacgtca tcaaagttcc cctgcagaaa      180

cgcgctgtcc ccagcatgag gtgcgagacc gtattcaaat tgactccgga gtttttcagt      240

ccaggaaaga gcaggggctt ggactcccaa cagtgcgcac agcgccagcg ctggggttat      300

aggcgttccc tgcaagagtc ttgggctcag aatttgctgt ctccccagca tccatgtccg      360

ggtccccctt caggggttca tactcactcc gaaccaatat tttgcactac cagtatcagt      420

aacacctgcc ttctgcccca aaacagcagc tggaaagcct ggcaggtgcc atggtgcctt      480

catgatgggc agactcggcc tgcactggat atgtgccaag aaatggagca gctgctgctg      540

cactcacagg agcgtctcgt gagtttagag cctgttatct cagtccgctc tcggccgacc      600

agcatgacac tgactactag tttgcccaat ttactgtccg ccgagcgatt gcagttctgt      660

cctcagaggg cacccgca                                                    678


<210>  4526
<211>  1083
<212>  DNA
<213>  Homo Sapiens

<400>  4526
agtagctgta gccaggctag aaccatgaac cccggtggga gcggaggcgc caggtgctcc       60

ctgagcgctg aggtgaggag gcgccagtgt ctccaattga gcaccgtccc aggggcggac      120

ccccaaagga gcaatgagct gctgctgctc gccgccgccg gagaggggct ggagaggcag      180

gatcttcccg gagacccagc caaggaagag ccacagcctc ccccacagca tcatgtatta      240

tactttcctg gagatgttca gaattatcat gaaatcatga cgaggcatcc ggaaaactac      300

cagtgggaga actggtctct ggaaaatgtg gctactatcc tggcccacag atttccaaat      360

tcttacatct gggtgatcaa gtgcagtagg atgcatctcc acaaattctc ctgttacgat      420

aattttgtga aatcaaacat gttcggagcc ccggagcata ataccgactt cggggcgttc      480

aagcatctgt acatgctttt ggtgaacgca tttaatctgt ctcagaactc cctttcaaag      540

aagtctttaa atgtgtggaa taaggattct attgcatcaa actgtaggag cagtccatcc      600

cacactacca atggctgtca aggagagaag gtacggacat gtgagaaatc tgacgaatcc      660

gccatgagtt tctacccccc ttctctgaac gatgcgagtt tcacacttat cggcttctct      720

aagggatgcg tggttcttaa tcaattactg tttgaattga aggaggccaa aaaggataaa      780

aacattgatg cctttattaa atccatccga actatgtact ggcttgatgg tggacatagc      840

ggcggttcca atacatgggt gacctaccct gaagtgctga aagaattcgc acaaacaggt      900

atcatagtgc acacacacgt cacaccctac caggtgcgtg atcctatgcg cagctggatc      960

ggtaaggaac ataaaaagtt tgttcagatt ctgggagacc tgggcatgca agtgacttcc     1020

cagatccact tcaccaagga ggccccttct attgaaaacc atttccgcgt tcacgaggtc     1080

ttt                                                                   1083


<210>  4527
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  4527
gacgaggagg aagtccccga ggagtgggtg ctgttgcacg ttgtgcaagg ccaaatcggg       60

gccggcaact atagctatct taggctcaat cacgaaggca agattgtgtt gagaatgagg      120

agtctcaagg gagacgcaga cctgtacgtg tccgcttctt ctttgcaccc cagcttcgat      180

gattacgagc tgcagagcgc gacatgcgga ccagatgctg tgagcatccc tgcgcatttt      240

cggcggccag tgggaatagg cgtctacggg cacccgagcc atttggagag cgagttcgaa      300

atgaaagttt actatgacgg caccgtggaa caacatcctt tcggcgaagc tgcctatcca      360

gctgacgggg ccgatgccgg ccagaagcac gcgggggccc ccgaggac                   408


<210>  4528
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  4528
atggattcac tcgataggtc ctgccaagac tggtgtgata ggaaacagca ctggctcgaa       60

atcgggccac ctgacctggt cgagcggaag gggagcctca cgttgaggtc ccaccacaaa      120

aaatacagca agcctgtcct tgtttattcc tggcatcggg accgggaggc ctttcctaag      180

gggtacgaca tcgagggacc ggaaaaggta aaaaagctgt gtaactccac ttaccggagg      240

ctcggtactg acgagagtcc tatatggaca tctgagacgc atgaaaaact ctctcaaatg      300

tgcctgaata cagaatgggt ggaaatgaag tctaaggccc tcctgaacga agaaaccgtg      360

tcctcaggc                                                              369


<210>  4529
<211>  546
<212>  DNA
<213>  Homo Sapiens

<400>  4529
aacaaaccga gcctgagtgg cagacaggcc ccagcgcaag ctcagacctc tgaccttgtc       60

ccatccttat ttccacttgg actgtgggcc cccggctttt gcacgtggtc aagccctgac      120

gaggataagg tctggcgtcc cgcttgggag caaggaccaa aaggagagcc cgaccctcga      180

ggactgcgcc cccgaaagcc agtgcccggc accggaaatc gggattctgg cactaggaga      240

cggctccagg acgcaaccga acaagatcct cggccaggca acgatgtagc atctgcagag      300

accgccggtc ccccctcacc ctcaggtatt agggctcagg atagagcacc tcgccatcga      360

agagcccctc ctgcacgaat gccagtcgca cccgcaccaa gtgctgacgg agagcctctc      420

caagagcaag ggggtggttt gttccacaga accaggagtg tgtataacgg acttgagtta      480

aatacatgga tgaaggtaga gcgtctgttt gtggagaaat tccatcagag cttcagcctg      540

gataac                                                                 546


<210>  4530
<211>  873
<212>  DNA
<213>  Homo Sapiens

<400>  4530
cagcacgttt ccgattggac atacagtgaa ggtgcactgg acgaggctca ctggccacag       60

cactatcccg cgtgcggtgg gcagcgacag tctccgatta acctgcaacg taccaaggtg      120

aggtataacc caagcctcaa gggactcaac atgacagggt atgagacaca ggccggtgag      180

ttcccaatgg tcaacaacgg gcataccgtg caaattagcc tgccttctac aatgcgcatg      240

acagtcgccg atgggaccgt ctatatagca caacagatgc actttcactg gggaggggct      300

agttccgaaa tttctggctc cgaacacacg gttgacggca ttaggcatgt aattgaaatt      360

catatagtgc actacaactc aaaatacaag agttacgaca tagcacaaga cgcgcctgat      420

gggctggccg tccttgcggc tttcgttgag gtgaagaatt acccagagaa tacatattac      480

tccaatttca tttctcacct ggccaatatt aagtatccag gccaacgcac taccttgaca      540

ggcctggatg tccaggatat gttgccacgc aatctccaac attactatac atatcacggg      600

tccctcacca cgccaccctg tactgagaat gtgcattggt ttgtcctcgc cgactttgtt      660

aagctctccc gtacccaagt ttggaagctc gagaactcat tactcgacca tagaaataag      720

acgattcata atgattacag gcggacccag ccactcaatc atcgcgtggt tgagtcaaat      780

tttcccaatc aagagtacac cctgggctca gaatttcaat tctatttaca caaaatcgag      840

gaaatcctcg attatcttcg gcgggctctc aat                                   873


<210>  4531
<211>  261
<212>  DNA
<213>  Homo Sapiens

<400>  4531
atggttaaac ttggttgttc cttctccggc aagccaggca aggaccctgg cgatcaggac       60

ggcgcagcca tggactcagt ccccctgatc agccccctgg atatttctca gttgcagcct      120

ccattgcccg accaggtggt gatcaagaca cagaccgaat accaactttc ttccccagat      180

cagcagaatt tccctgatct tgagggtcag agacttaact gttcccaccc cgaggaaggt      240

cgacggctgc caacagcgag a                                                261


<210>  4532
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  4532
cagaatgaca ccgagccgat tgtactggag ggcaaatgtc tggtcgtttg tgatagttcc       60

ccgagtgccg acggcgccgt cacctcttcc ctcggtatct ctgtcaggag cggctccgcc      120

aaagtggcct ttagtgcaac cagatctaca aaccacgagc ctagtgaaat gtctaatcgt      180

accatgacca tttacttcga ccaggtgctg gtgaacattg gtaatcactt cgatctggcc      240

tctagcatct tcgttgcccc tagaaaggga atctattctt tctccttcca tgtggttaag      300

gtatacaatc gtcaaaccat ccaagtgagc ctgatgcaga acggctaccc agtgataagt      360

gcttttgcgg gggaccagga tgtaaccaga gaagcagcct ctaacggcgt cctcctgctc      420

atggaaagag aagataaagt ccacctcaaa ctggaaagag gaaacctgat gggggggtgg      480

aaatactcta ccttttccgg atttcttgtg ttcccactg                             519


<210>  4533
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  4533
caggagggaa gtgaacctgt cctgcttgag ggggagtgtt tggtggtgtg cgagcccgga       60

cgggctgccg ccgggggacc tgggggcgcc gctctgggag aggctcctcc gggccgggta      120

gcatttgctg ccgtgcgtag ccatcaccac gagcctgctg gcgaaactgg aaacgggaca      180

agcggcgcta tttattttga ccaggtcctc gtgaacgagg gaggtggatt cgacagagct      240

tctgggagct ttgtggctcc tgtgaggggc gtgtactcat tcaggttcca cgtggtcaaa      300

gtctacaatc ggcagaccgt gcaggtttct ctcatgctga acacctggcc agttatcagc      360

gcatttgcta atgatcccga cgtcaccagg gaggccgcta cttccagcgt gctgctgcct      420

ttggacccgg gggatagggt gagcttaagg ctgcgcaggg gaaacctgct ggggggctgg      480

aagtattcat cattcagtgg cttcttgatt ttcccactc                             519


<210>  4534
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  4534
gcccaacctg aagatcgtcg agtgttacgg tatccaggaa ctgccgtcat ggttacatgc       60

ccaaatcgac cactcgtgcc tcgtcctctg cttactcccg gtggttcccg ggctagcttg      120

gctctctgtg catttgtcgc tgtccctcag aggataccgc agcctctgtt gccggcctac      180

attttactta tgctgccgag tctggtagtg gatatggcac tgccaagcag tcggttactt      240

cgatctatta aacccatcca gcccgccagc caagtagtgc gcaaggagcg taatcctaac      300

cccaattgcc cacagtccga ccctctcatg aaagccagca gcacttcttt tctgagtcat      360

acttacctca ttaataagac acgcagcact acgagaaaag tcgaagagca ttcctggttc      420

acatgcacgg gtgccaaata tttcgccata cctctggccg agcgtaacac taaacggctc      480

actaagagaa gcacacacgc ccaactcctc cggggtaagc aagacgggag cgaatgggta      540

gtgccacgga gtagcgcaag cagcaatgtg ctgtatcat                             579


<210>  4535
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  4535
gtgaatggat gttgcggact gcaaatgatc gcactttggg cccagtcatc cggaaatgcg       60

gatgcaaggg tagaggagat cttagctggc gaggaacgca ggcttgctgc tctgttaggc      120

agtcagggca tgcggttttg ggtatgtctt gccgcatgca gagcaatgtg gggacttgcc      180

gctagacggg gccgagcaga ggattcctca agttcacccg tggacgctag taaattcccg      240

tggaggggag ggcagcacag aactactatg atgccctgcc tgcttcgggt tggcgtgttt      300

agaccttgtc acgtacggcc caccggagac ccatcctgcg acgttcagcc ccctagactg      360

gggtttagca gagtacccga tacccaagtt gctttttatg gctctggcca ttgggacccg      420

acgccgttta gcgtgcattc ttgcttcttt aacttccagg tacgaaaaat cattttcttg      480

ctg                                                                    483


<210>  4536
<211>  807
<212>  DNA
<213>  Homo Sapiens

<400>  4536
ggacatctgt ccagtcctcc actggtggat acactgcatg gaaaggttct ggggaaattc       60

gtaagccttg aaggcttcgc ccagcctgtc gctgttttcc ttggaatccc attcgccaag      120

ccgcctctcg gtccattgag gtttaccctg cctcagcctg ccgaaccttg gaattttgtg      180

aaaaatgcca cgtcctaccc ccccatgttt acccaggatc caaaggctgg acaattgatc      240

tctgagttat tcacaaaccg caaggaaaat attcccctga agctcagcga agactgcctc      300

tacttgaaca tttatacccc tgcagatctt accaagaaga accggcttcc tgtgatggta      360

tggatccacg gcggaggcct catggttggt gctgcttcca cttatgatgg tcttgcactg      420

gccgctcatg agaatgttgt ggtagtgacc atacagtacc gcttagggat ttggggcttt      480

ttctcaaccg gggacgagca cagtccagga aactggggac atctcgacca actggccgca      540

ctgcattggg tccaagataa catcgccagt ttcggcggaa acccgggatc tgttactata      600

ttcggtggca gcgtcggcgg agaatcagtt tccgtgctgg tgctgagccc tctggctaaa      660

aacctgttcc accgtgcaat ctctgaaagc ggtgttgcct tgacaagcgt gctggttaag      720

aagggagacg tcaaaccgct ggccgaggtg ggactgaggc ttgtgcgatt acgcctcgac      780

acccccacct ccctggccct gtgtagc                                          807


<210>  4537
<211>  1623
<212>  DNA
<213>  Homo Sapiens

<400>  4537
gcacttcata ccaagaggcc tcaggtagta accaaatatg gcacactcca gggaaaacaa       60

atgcatgtgg ggaagacccc tatccaggtt ttccttggcg ttcccttcag caggccacct      120

ctcgggatac tgagatttgc cccccctgaa ccacctgagc cttggaaagg catcagggac      180

gccactacat acccacctgg ttgcctgcag gaatcatggg gccagctggc gagcatgtac      240

gtgagcaccc gggagcgcta taagtggctg cgattcagcg aagattgcct ctacctcaac      300

gtgtatgctc ctgcccgcgc accaggcgac ccgcagctgc ctgttatggt ctggtttcct      360

ggcggagcat tcattgtagg cgccgccagc tcttacgaag gctccgacct cgccgctcga      420

gagaaagtcg tccttgtgtt cctgcagcac cgcttgggaa tctttggctt tctgtccaca      480

gacgattccc acgcccgcgg caactggggc ctgctcgatc agatggctgc tctcagatgg      540

gttcaagaga acatcgcagc ctttggaggt gacccaggca atgtcaccct cttcggccag      600

agcgccggcg caatgtccat ttctggactg atgatgtcac ctctggcgtc cggtttattc      660

catcgcgcta tatctcagag tggcaccgca ctgttcagac tgttcatcac atccaaccct      720

cttaaagtgg ccaaaaaggt agcccatctt gctggctgta accacaactc aacccagatt      780

ttggtgaatt gtctcagggc gttgagtggc acaaaggtga tgcgcgtgag caacaaaatg      840

cgatttcttc agttgaactt ccagcgcgac cccgaggaga taatctggtc tatgtcacct      900

gtggttgacg gcgtcgtcat tcctgacgac cccctggtgc tcttaacaca aggcaaggtg      960

tcctctgtcc cttacttgct gggagtcaac aatcttgagt tcaattggct cctgccatac     1020

attatgaaat tcccactgaa ccggcaggca atgcggaagg aaacaattac caagatgctg     1080

tggtcaactc ggacattgtt gaatattaca aaggagcagg ttcccttagt tgtggaagag     1140

tatctggata atgtcaacga acatgactgg aaaatgctcc gtaataggat gatggatatt     1200

gtgcaggatg ccacctttgt gtatgccact ctgcagactg ctcactacca ccgtgatgcg     1260

ggcttaccag tgtatttata tgagtttgag caccacgcga gagggataat cgtgaagccc     1320

aggaccgatg gggccgacca tggcgacgag atgtacttcc tgttcggcgg cccttttgct     1380

accgggctgt ccatgggcaa ggagaaagct ctgagccttc agatgatgaa atactgggcc     1440

aacttcgcac gaacaggtaa ccctaacgac ggaaatctgc catgttggcc aaggtacaat     1500

aaggatgaaa agtacttgca actggacttt actacccggg tcggcatgaa gctgaaggag     1560

aagaagatgg cattctggat gagcctttac cagagtcagc gacctgagaa gcaaaggcag     1620

ttc                                                                   1623


<210>  4538
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  4538
gcacctacta aaggcccttc cgccgagggc ccccaaagga atacgcggct tggctggatt       60

caggggaagc aggtcaccgt ccttggatcc ccagtccccg ttaatgtctt cctgggcgtt      120

ccgtttgcag ccccacccct gggcagcttg aggttcacaa acccccagcc cgcgtcaccc      180

tgggataacc tccgtgaagc cacttcttac ccaaatctgt gtcttcagaa ttcagaatgg      240

cttctcttgg atcaacacat gctgaaggta cattacccta aattcggcgt gagcgaggat      300

tgcctttacc tgaatatcta tgcgccagca cacgcagaca cagggagcaa attgcctgtg      360

ctggtgtggt tcccgggagg cgccttcaag accggaagcg catctatatt tgatggtagc      420

gccctcgcgg catatgaaga tgtgctcgtg gttgtggtcc agtaccgact tggtattttc      480

ggcttcttta ccacgtggga ccagcacgct cccggtaatt gggccttcaa ggatcaggtc      540

gcagcactgt cttgggttca gaagaatatc gaattctttg gcggggaccc atcaagcgtt      600

actatattcg gcgagagcgc aggcgcaata agcgtatcaa gtctcattct tagcccaatg      660

gctaaagggc tgtttcacaa agcaatcatg gagagcgggg tagctatcat cccctattta      720

gaggcccacg actatgagaa gagcgaggat ctgcaggtgg tggcccactt ctgcgggaac      780

aacgcatcag actcagaggc cctgttacga tgcctgcgga caaaaccatc taaggagttg      840

ctgacactca gtcagaaaac caagtcattc acaagggttg tagatggggc cttcttcccc      900

aacgagcctc tggaccttct gtctcagaaa gcctttaaag ccatcccctc cattatcggc      960

gtgaacaacc acgaatgtgg atttctgctc cccatgaagg aggcccccga gatcctgtct     1020

ggctccaata agtcccttgc cctgcacctg atacagaaca tccttcatat cccacctcaa     1080

tacctgcacc tcgtggctaa cgagtacttc cacgataaac acagtctgac cgaaatccgg     1140

gatagcctcc ttgacctcct gggggacgtg ttctttgtgg tcccagcttt gatcaccgcc     1200

cgctatcata gagatgctgg ggcccctgtg tacttctacg agttcagaca tcggccccag     1260

tgcttcgaag atacgaaacc agcatttgtg aaagccgatc atgcagacga agttcggttc     1320

gtgtttgggg gggcattcct gaagggagac atcgtgatgt tcgagggagc cacggaagaa     1380

gagaaactgc tcagccgcaa aatgatgaag tactgggcca ccttcgcaag gaccggaaac     1440

ccaaatggga acgatctgag tctctggccc gcttacaatt tgaccgagca gtacctccaa     1500

cttgatctta acatgtctct gggacagcgg cttaaagaac ctagggtgga cttctggact     1560

tctacaatcc ccctgatact ctctgcctcc gacatgttgc acagccccct gtctagtctg     1620

accttcctga gcctcttaca accctttttc tttttctgcg cacca                     1665


<210>  4539
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  4539
gcccccgacg tgcaggattg tcctgagtgt actttgcagg aaaacccatt ttttagccag       60

cccggggccc ctatcctgca gtgtatgggc tgctgttttt cacgcgctta ccctacccct      120

ctgcgctcta agaaaacaat gctggttcaa aagaacgtta ctagtgagtc cacgtgttgt      180

gttgcgaaaa gttacaaccg agttaccgtg atgggcgggt ttaaagtgga gaatcacaca      240

gcttgccatt gttctacatg ttattatcat aagagt                                276


<210>  4540
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  4540
tcaaaggaac ctctgcgtcc aagatgcagg ccaattaacg cgactctggc cgtggaaaaa       60

gaggggtgcc cggtctgcat taccgtgaat accaccatat gtgcgggata ttgccctacg      120

atgactcgcg tgctgcaagg agtcctgcca gctctgccac aggtggtttg caattatcgg      180

gacgtgaggt ttgagtccat cagattgcca ggctgcccca ggggtgtaaa ccctgtggtc      240

agctatgccg tggccttgtc ctgccaatgt gctttgtgta ggcgctcaac tactgattgt      300

ggtggaccaa aggatcatcc cttgacgtgt gatgatccta ggtttcagga ctccagctct      360

tctaaggcac cgcccccaag tctgcctagc cctagcagac tgcctggacc a               411


<210>  4541
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  4541
agcaaagaac ctcttagacc ccgttgtcgc ccgatcaatg cgaccctggc ggttgagaaa       60

gaggggtgcc ccgtatgtat caccgtgaac accaccattt gcgcgggcta ttgcccaacc      120

atgacccgag tgctgcaagg agtgcttccg gctctgcccc aagtggtgtg taactaccga      180

gacgtccgct tcgagtctat taggctgccc ggctgcccaa ggggcgtcaa tccagtggtg      240

tcatatgccg tcgctttgtc ctgccagtgt gctttgtgtc gtcggtctac taccgactgt      300

gggggcccca aggatcaccc gctgacatgt gacgacccac gattccaagc gagctctagc      360

tctaaggctc ctccacctag tttgccatct ccttctcggc tgcctggccc ctcagatacc      420

cctatcctgc cccag                                                       435


<210>  4542
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  4542
tctaaggagc ctctgaggcc caggtgccgt cctatcaacg ctacacttgc tgttgagaag       60

gagggatgtc ctgtatgcat cacagtgaat acaacaatct gcgctggcta ttgcccaacc      120

atgaccaggg ttctccaggg tgtcctccca gctttgcctc aggtggtttg taattacaga      180

gacgtgcgat tcgagtctat tcggctccca ggctgcccca gaggtgtgaa tccagtggta      240

agctacgctg ttgccttgtc ctgtcagtgt gcactctgca ggagatctac aactgactgc      300

ggcggaccca aggatcaccc attgacttgt gatgatcccc gcttccagga cagcagctca      360

tccaaggctc ctccgccctc cctgccctca ccttcaaggt tacctggacc ctctgacaca      420

cctatactgc cgcaa                                                       435


<210>  4543
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  4543
tctcgagaga tgctcaggcc aagatgtcgg ccaatcaatg cgactttggc cgttgaaaag       60

gaggggtgcc ctgtgtgcat caccgtgaac accactattt gtgccgggta ttgccctact      120

atgacccggg tgctccaggg agttctgccc gcactgcccc aggtggtgtg taattatagg      180

gacgtgaggt tcgaaagtat ccggctgcca ggatgcccac gcggggtgaa ccctgtggta      240

agctacgcag tagctttgag ctgtcagtgc gctctttgcc gcagatcaac cactgattgc      300

ggaggcccga aagatcaccc gctgacgtgc gatgacccca gattccaagc ttccagttcc      360

agcaaggcgc ctccacctag cctccccagc ccttcacgtc tcccaggccc aagtgataca      420

cccattttac cccaa                                                       435


<210>  4544
<211>  1365
<212>  DNA
<213>  Homo Sapiens

<400>  4544
tatcagctga cttgctactt caccaactgg gcacaataca gacccggcct gggcagattc       60

atgcccgaca atatagaccc atgtttgtgc acccatctta tatatgcctt tgcaggacgg      120

cagaacaacg aaatcacaac gattgagtgg aatgacgtaa ccctgtatca ggccttcaat      180

ggactgaaga ataagaacag ccagcttaag acattgctgg ccatcggggg atggaacttc      240

ggcactgcac cctttacagc gatggtgtcc acaccagaga atagacagac atttatcaca      300

tccgtgatta aatttttgcg tcagtacgaa ttcgacggac ttgatttcga ttgggagtac      360

ccgggatctc gaggaagccc cccgcaagac aagcatttgt ttaccgtgct ggtacaggaa      420

atgagagagg ccttcgaaca agaggcaaaa caaattaaca agcctcgatt gatggttacc      480

gccgccgtag cagccggtat cagcaatatc cagagcggct atgagatccc ccagctttca      540

cagtacctgg actatatcca cgtgatgacc tacgacctcc acggaagttg ggaaggttat      600

acaggcgaga acagccctct gtacaagtac ccaacagata ccggtagcaa tgcctatctg      660

aacgttgatt acgtaatgaa ctactggaaa gataacggtg ctccagccga aaaattgatt      720

gtgggattcc caacctatgg ccataatttt attctgagca acccctcaaa tacgggaatt      780

ggtgcaccta catcaggtgc cggcccagct ggtccctatg cgaaagagtc tgggatctgg      840

gcctactacg agatttgtac ttttctgaag aacggagcta cacagggatg ggacgccccc      900

caggaagtcc cctatgcata ccagggcaac gtatgggttg gatatgataa tatcaaatcc      960

tttgatatca aggctcagtg gctcaaacat aacaagtttg gaggggccat ggtgtgggca     1020

attgacctgg acgactttac gggaaccttc tgtaatcaag gtaagttccc actgatctct     1080

acactcaaga aagcactggg tctccaatcc gctagttgta cggcacccgc gcagcctatc     1140

gagcccatca ctgccgcacc ttctggtagc ggcaacggaa gcggttcttc tagttcaggg     1200

gggagttccg gcggcagcgg cttctgcgcc gtaagagcta atgggctgta tcctgtcgct     1260

aacaatcgta atgctttttg gcactgcgtg aacggtgtta cctatcagca gaactgtcag     1320

gccggtttgg tctttgatac gtcctgcgac tgttgtaact gggcg                     1365


<210>  4545
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4545
tccgagcacg agaccagact ggtggccaag ctgtttaaag actactcatc cgttgtgagg       60

cctgtggaag atcaccgcca ggtagtggag gtcactgtcg ggctccagct cattcagctc      120

atcaatgttg acgaggtgaa ccaaatcgtc acaactaacg tgcgactcaa acagggggat      180

atggtcgacc tgccgcgccc aagttgtgtc accttgggcg tgcctctttt ctcccacctg      240

cagaacgagc aatgggtgga ttataactta aagtggaatc ccgacgatta tggaggcgtg      300

aaaaaaatcc atattccctc cgagaagata tggcggccag acttagtgtt atacaataat      360

gctgatggcg atttcgcaat agtgaaattt actaaggtac tgctgcagta caccgggcac      420

atcacctgga cccctcctgc catttttaaa tcatactgtg agatcatcgt gacgcatttt      480

ccatttgatg aacagaactg ttctatgaaa ttaggaacat ggacttatga tggatctgtt      540

gtggctatta atcctgagag cgatcagccc gacctgagta atttcatgga atctggcgag      600

tgggttatta aggaatcaag gggctggaaa cacagtgtca cgtacagctg ctgccccgat      660

actccttact tagatatcac ctaccacttt gtgatgcagc gattg                      705


<210>  4546
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  4546
gaggaggcca agcggccacc acctagggcc cctggggacc ctctgtcaag cccttcccct       60

acggctcttc cacagggcgg gagccatacc gagactgaag acaggttgtt caagcacctg      120

tttcgcgggt acaatcgttg ggcaaggccc gtccctaata ctagcgacgt ggtgattgtg      180

aggttcggtc tgagcatcgc ccagttgatt gatgtcgatg agaagaacca gatgatgacc      240

accaacgtat ggctcaaaca ggagtggagc gactataaac tgagatggaa tccgaccgat      300

tttggcaaca ttacatccct gagggtccct tccgagatga tctggatacc ggacatagtg      360

ctgtacaata acgcagatgg cgaatttgct gttactcaca tgacaaaagc ccatctgttt      420

tcaaccggaa ctgttcattg ggtgccaccc gcgatatata agagttcctg ctctatcgat      480

gttacttttt tcccattcga ccagcaaaac tgcaagatga aattcggatc ttggacatac      540

gacaaagcca agatcgacct ggagcaaatg gaacagactg ttgacctgaa agactactgg      600

gagtctggag agtgggcgat cgtaaatgca accggcacgt ataatagtaa gaagtatgat      660

tgttgcgcgg agatttatcc cgacgtgaca tatgctttcg ttattcggag gctt            714


<210>  4547
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  4547
aaaaacgagg aactgaggct ttaccatcat ctgttcaata actacgatcc agggtcccgc       60

cccgtacggg aacccgaaga tacagtgaca atctcactta aagtcaccct taccaatctg      120

atctctctga acgaaaagga ggagacactc acaacttcag tgtggatcgg aattgattgg      180

caggactatc gcctgaatta ctccaaagat gattttggtg gcattgagac tcttcgagtg      240

ccttccgagc tcgtgtggct gcccgaaatt gtcctggaaa ataacattga cgggcagttc      300

ggcgtagcat atgacgccaa cgtcctggtg tacgaaggag gtagtgttac ttggctgcct      360

ccagcaatct atcgctccgt ttgtgcggtc gaagtcacct actttccttt cgactggcag      420

aattgtagcc ttatttttag gagccagacc tataacgcag aggaagtcga gttcacattt      480

gctgtggata acgacggaaa gacaataaat aaaatagata ttgacactga ggcgtacacc      540

gaaaacgggg agtgggcaat cgacttttgt ccaggcgtga tacgtcgcca tcatggaggc      600

gctactgacg gacccggcga gacagatgta atatatagct taatcatccg aagaaaa         657


<210>  4548
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  4548
agaaatcagg aggagcgact cttagccgat ctcatgcaaa actacgaccc taatctgcgt       60

ccggccgaga gagactcaga cgtggttaat gtgagtctga aattgacatt gactaacctg      120

atttccctca acgaacgcga ggaagctttg actacaaacg tttggataga aatgcagtgg      180

tgcgactaca gattgagatg ggatccacgg gactatgagg gcctgtgggt tctgagagtg      240

ccaagcacaa tggtgtggcg gcccgatatc gtccttgaga acaacgtgga tggggtgttc      300

gaagttgccc tgtattgtaa cgtactggta tccccagatg ggtgtattta ttggttgccc      360

cccgccattt tccggagtgc ctgctccatc agcgttacct acttcccatt cgactggcag      420

aactgttcat tgatctttca aagccagaca tacagcacta acgagattga cctgcagctg      480

agtcaggaag atgggcaaac tattgaatgg atctttattg accctgaggc gttcactgag      540

aacggcgaat gggccatcca gcaccggccc gccaaaatgc tgttagaccc cgccgctcct      600

gcccaagagg ctggtcatca gaaggtcgtg ttttatcttc tcatccagcg gaaa            654


<210>  4549
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  4549
tcttctctcg taaccctcaa caataacgga tatgatggta ttgtgatagc tatcaatccc       60

tcagtcccag aggacgaaaa actcattcag aatattaagg agatggttac agaagccagc      120

acccacttat tccacgccac taagcagagg gcatatttcc ggaatgttag tatcctgatt      180

cctatgacat acaagtcaaa aagtgagtac cttatcccga aacaagaaac ttacgaccaa      240

gccgacgtca tagttgccga tctgtacctt aaatatgggg atgatcctta tactctgcaa      300

tatggtcagt gcggagataa gggacagtac attcacttca caccgaactt tctgctgact      360

aataacttag ctacctacgg ccctagaggg aaagttttcg tgcacggatg ggcacatctc      420

cggtggggag tattcgacga gtataatgtt gatcagccgt tttatatctc tcgcaggaat      480

accacggagg ccaccagatg ttcaactagg attactgtgt acatggtgct gaacgaatgc      540

aagggagcgt cttgtatcgc tagacctttt cgcagggact ctcagactgg gttgtatgag      600

gccaagtgca catttattcc caagcgcagc cagactgcta aggagagcat cgtttttatg      660

caaaatttgg attccgtcac agaattctgc accgagaaga cccataacaa agaggcacct      720

aacctt                                                                 726


<210>  4550
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  4550
tggtctaagc acgcaaagcc agtcgcgtgc agtggcgatt ggctgggcgt gcgagacaag       60

tgcttttatt tctccgatga tactcgtaac tggaccgcga gtaagatctt ctgcagcctg      120

cagaaggccg aactcgccca gatagatacc caggaggata tggagtttct gaagagatac      180

gccggcactg acatgcattg gattgggttg tctaggaagc agggcgatag ctggaaatgg      240

actaatggca ccacttttaa cggctggttt gagattattg gaaacggatc ctttgctttt      300

ttgtctgccg atggggtgca cagcagtagg ggattcatcg atattaaatg gatctgtagc      360

aagcccaagt acttcctt                                                    378


<210>  4551
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  4551
gccctcccgc agtataagaa gaaaatcact gatcgttgct ttcaccattc tgaatgctac       60

agcggatgtt gccttatgga cctggattct ggcggcgcct tctgcgcccc tcgcgcacgg      120

attacaatga tctgtctgcc ccagactaag ggcgccacca acataatctg tccctgccgc      180

atgggcttaa cgtgtatatc taaagacctg atgtgctcca gacgatgtca catgatc         237


<210>  4552
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  4552
gaactgtgtc aacccggagc ggaaaatgcc ttcaaggtga gactgtcaat ccgaactgct       60

ctgggggata aagcatatgc gtgggacaca aatgaggaat acctctttaa ggccatggtg      120

gccttcagca tgcggaaggt ccccaatagg gaagccactg agatcagcca tgtattgctc      180

tgcaacgtta ctcagcgagt cagcttttgg tttgtagtaa ccgatccgag taaaaaccat      240

acacttccag cagtcgaagt gcagtctgct attagaatga acaaaaatcg aatcaacaac      300

gcatttttct taaatgatca gaccctggag tttctgaaga ttcccagcac cctggcccca      360

cctatggatc cctccgtccc t                                                381


<210>  4553
<211>  1338
<212>  DNA
<213>  Homo Sapiens

<400>  4553
gctcctacgt ggaaggacaa aactgctatc agtgagaacc tgaaatcatt tagcgaggtc       60

ggcgagattg atgcagacga agaagtcaag aaagccttaa ccgggataaa gcagatgaag      120

atcatgatgg agcgaaaaga gaaagaacac accaacctga tgtcaacatt gaagaaatgt      180

agagaggaaa agcaggaggc attgaagctc ttaaatgaag tgcaggagca cctcgaggag      240

gaagagcgtt tgtgccgtga atccttggct gattcttggg gagaatgccg aagctgtctg      300

gaaaacaatt gtatgagaat ctatactacc tgtcaacctt cctggagttc tgtgaagaac      360

aagatcgagc ggttcttccg caagatctac cagttcctgt ttccattcca cgaagacaac      420

gaaaaggacc tgcccatttc tgaaaaatta attgaggaag atgctcaatt gacacagatg      480

gaagatgtct tctcacagct tacggtcgac gtgaacagtt tgtttaatag atcatttaac      540

gtgtttcgcc agatgcagca agaattcgat cagaccttcc aaagtcattt tatatctgac      600

acagatctga ctgagcctta ctttttcccg gccttctcca aagaacccat gactaaggca      660

gatctcgagc agtgttggga cattcccaac tttttccagc ttttttgtaa cttttctgta      720

agtatttacg agtctgtctc tgaaacaata acaaagatgc tgaaagccat agaggatctg      780

ccgaaacagg acaaggctcc tgatcatggg ggactcatct caaagatgct tcccggccag      840

gaccgcgggc tgtgcggcga gcttgatcaa aacctgtctc gatgttttaa gtttcatgag      900

aaatgtcaaa agtgccaggc ccacctctca gaagactgcc ctgacgttcc cgcactccac      960

actgagctcg acgaagcaat aaggctcgtg aatgtgtcca accagcagta cggccagatc     1020

ctgcagatga ccagaaaaca cctcgaagac actgcttacc tggtggaaaa aatgaggggt     1080

cagtttggat gggtgtctga gttagctaac caggcccccg agaccgagat tatctttaac     1140

tccatccagg ttgtccctcg cattcacgag ggcaatatta gtaagcagga tgagacaatg     1200

atgactgatt tgtctatcct ccctagctcc aattttaccc ttaaaatccc cttggaggaa     1260

tctgcagaaa gtagcaactt catcggctat gtggtcgcca aggccctgca gcactttaaa     1320

gagcacttta aaacctgg                                                   1338


<210>  4554
<211>  1578
<212>  DNA
<213>  Homo Sapiens

<400>  4554
gaaggtgcag cgccaattgc tattacttgc ttcacgagag gacttgatat ccgcaaagag       60

aaggctgatg tcctctgtcc tgggggatgc cccctggaag aattctcagt ttatggcaat      120

attgtgtacg ccagtgtgtc ctctatttgc ggggctgccg tccatagggg cgtgattagc      180

aacagcggcg gtccagtccg agtgtactct ctgccaggcc gcgaaaacta ttccagcgtg      240

gacgccaacg gaatacaatc ccagatgctc tctcggtggt ccgcttcctt tactgttaca      300

aaaggtaaaa gcagcacaca ggaggcaact gggcaggctg tcagtaccgc tcatccaccg      360

acagggaaga gactcaaaaa gactccggag aaaaaaactg gaaacaagga ctgcaaggct      420

gatatcgcct tccttatcga cggatctttc aatatcggac agcgcagatt caatctgcag      480

aagaactttg tcgggaaagt ggccctgatg ctcggaatcg ggacagaagg tccccacgtg      540

gggctggtac aggcatcaga acatcctaaa atagaatttt atctgaaaaa cttcacaagc      600

gctaaagatg ttcttttcgc cattaaggag gtcgggttta gaggcggcaa ttcaaatacc      660

ggcaaggcac tcaaacacac ggcccaaaaa ttctttaccg tggatgcagg cgtaagaaag      720

ggcattccta aagtagtggt tgtgtttatc gatggctggc cttccgacga catcgaagaa      780

gcgggaatag tcgcccgaga gtttggagtt aacgtgttca ttgtgtctgt cgcgaagcca      840

atcccagagg aattaggaat ggtgcaggat gtaacatttg tggataaagc cgtatgtcga      900

aataatggat tctttagtta tcatatgccc aattggttcg gcaccacaaa gtatgtgaag      960

ccccttgtgc agaagttatg tactcacgaa cagatgatgt gctctaagac atgttacaat     1020

agcgtgaaca tagcttttct cattgatggc agcagctccg tgggggattc caacttcagg     1080

ctgatgctcg aattcgtttc taatatcgcc aaaacattcg agattagcga tattggcgct     1140

aaaattgctg ccgtgcagtt cacatatgac caacgaactg agtttagttt cacagactac     1200

agcaccaagg agaacgtgct ggcggtcatt aggaacattc ggtacatgag cggaggcacg     1260

gcaaccggag atgctatttc cttcactgtg cgaaacgtgt ttggtcccat ccgggagtcc     1320

ccaaacaaaa acttcctggt catcgttaca gacgggcaga gttatgacga tgtgcagggg     1380

ccggcggctg cggcacacga tgccggcatc accatattct ccgtgggggt agcatgggct     1440

ccactggatg acctgaaaga catggcctca aaacccaagg aaagtcatgc atttttcaca     1500

cgcgagttca ctggcctgga gcccatcgtt agcgatgtga tcagaggaat ttgccgggat     1560

tttctggaga gccagcag                                                   1578


<210>  4555
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  4555
accggatttc tgtacccctt cagcgcagcc gccttgcagc agcacggata ccctgaaccc       60

ggcgcggggt cccctggtag cggatatgcg tcacggcgcc attggtgtca tcacactgtg      120

acccggactg tcagctgtca ggtgcagaac ggcagcgaaa cagtggtgca gcgggtgtac      180

caatcctgcc gatggcccgg cccttgtgcc aacctggtga gttaccgtac tttgataaga      240

cccacctacc gagtgagtta ccgcacggta accgtgctgg agtggcgctg ttgtcccggc      300

ttcacaggaa gcaattgcga cgaggaatgt atgaactgca cacgcctgtc tgacatgagt      360

gagcgcctta ccactctcga ggcaaaggtg ctgctgctcg aggcagcgga gaggcccagt      420

tcacccgaca atgatctgcc cgcaccagaa tctacgcccc cgacttggaa tgaggatttc      480

ttgcctgatg ccattccact cgctcaccct gttccacggc agcgtagacc tacaggaccc      540

gccggccccc cagggcagac cgggccccca ggcccagccg gcccccctgg ctcaaaaggc      600

gatcggggcc aaactggcga gaaagggcct gcaggaccgc ccggtctgct ggggccccct      660

ggaccccgtg gcttaccagg tgagatgggc cgccctggcc cgccggggcc tcctggcccc      720

gctggaaatc ctggccccag tcctaatagt ccgcagggag cactgtatag tctccagccg      780

cctacagata aggacaatgg agactctaga ctggctagtg ctatcgtgga taccgtactg      840

gctggagtgc cagggccacg cgggccccct ggccccccag gtccccccgg gccgagaggc      900

ccacctggac ctcctggtac gccgggctct cagggcttgg ctggcgagag aggaacagta      960

ggcccaagcg gagagccagg cgtgaagggc gaagaaggag aaaaggcagc caccgctgaa     1020

ggagagggag ttcagcagtt gcgggaggcc ttaaagattt tagcggaaag agtcctgatt     1080

ctggagcata tgattggcat ccacgaccca ctcgcgtctc ctgagggcgg ctccggccag     1140

gacgccgcgc tgcgagcaaa tttgaaaatg aaaagaggtg gagcacaacc tgacggggtt     1200

ctggcagctc tgttggggcc tgacccaggt caaaaatcag tggaccaggc aagcagtagg     1260

aaa                                                                   1263


<210>  4556
<211>  1611
<212>  DNA
<213>  Homo Sapiens

<400>  4556
gatcagtgca acgttcccga atggctgccc ttcgctagac caactaacct taccgacgac       60

ttcgagtttc cgatcggcac ttatctgaac tacgagtgcc gacctggcta ttcaggccgg      120

ccattcagca ttatctgcct gaagaattca gtctggacgt cagcgaagga taagtgtaag      180

agaaagtctt gccggaaccc ccctgatccc gtcaacggaa tggcgcacgt gattaaggac      240

atccagttta ggtcacagat caaatacagt tgcccgaaag ggtacaggtt aataggctca      300

agcagtgcaa cctgcatcat cagtggaaac accgtgatct gggataataa gactcctgtg      360

tgcgacagga tcatttgtgg tcttcctcca acaattgcca atggggattt cacttctatc      420

tcaagagaat acttccatta cggatcagtg gtaacatacc actgtaatct tgggtcacgt      480

gggaaaaagg tgttcgagct tgtcggcgag ccaagcatct attgtacatc caaggacgat      540

caagtcggca tctggtcagg gcctgctccc caatgtataa tccctaacaa gtgtacgcca      600

cctaacgtag aaaacggtat tcttgtatct gataaccgaa gcctcttcag tctgaatgaa      660

gtggtggagt tccgctgcca gccggggttc ggaatgaaag ggccctctca cgttaaatgc      720

caagccttaa acaagtggga gcccgaatta cctagctgct cccgggtgtg tcagcctccc      780

ccagacgtcc tgcacgccga gagaacccag cgtgacaaag acaatttttc ccctggacag      840

gaggttttct atagctgtga gcctggatac gaccttagag gaagtacgta cctgcactgc      900

acaccacagg gggattggag tccagccgcc ccccgttgtg aagtgaagtc ctgtgacgat      960

ttcctcgggc aacttccaaa tggacacgtt ctctttcctt tgaacctgca gctcggtgct     1020

aaggttgact ttgtttgcga cgaggggttc cagctcaagg gatcctccgc ctcctattgt     1080

gttctggcgg gaatggagag cttgtggaat tcatccgtac cagtgtgcga aaggaaatca     1140

tgtgagactc cacctgttcc cgtgaacggc atggtgcatg ttataaccga cattcatgtg     1200

ggcagtcgta tcaattattc ttgcaccaca ggccaccggc ttatagggca cagctccgca     1260

gagtgtatcc tgagtggtaa cacagcccac tggagcatga aaccgccgat ctgtcagcag     1320

atcttctgcc caaaccctcc agcgatcctg aatggcagac ataccggcac cccactggga     1380

gacattcctt atgggaaaga ggtctcatac acatgcgatc cccaccccga caggggtatg     1440

acctttaact tgattggcga gagcacaatc cgacgcacta gtgagcccca tggaaatggg     1500

gtgtggagtt cacctgcccc cagatgcgag ttgcctgttg gtgcaggttc ccacgacgcc     1560

ctgatagtag gcaagtttta cgaggtcttt gccgaagaat tttgtcatct t              1611


<210>  4557
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  4557
aagaagaaaa gcgcccggga tcagttcaat aagctggtga cagatctccc caacgttcag       60

gaggagatcg tgaatattca caatgctctg aggcgacggg ttgtgcctcc cgcatccaac      120

atgctgaaaa tgagttggtc cgaagaggcg gctcaaaatg ccagaatttt ttccaaatat      180

tgtgacatga cagagtctaa cccacttgaa cgacggctgc ccaacacttt ctgcggtgaa      240

aatatgcaca tgactagcta tccagtctct tggtcaagtg tcatcggagt gtggtattcc      300

gaatccacaa gctttaaaca tggggaatgg accaccactg acgatgacat aaccactgat      360

cactacacgc aaatagtttg ggccacttct tatctgatcg gctgcgcaat cgcttcctgc      420

cgtcagcagg gatccccaag gtacctgtat gtgtgccact attgccatga gggcaatgat      480

cctgaaacca agaacgagcc ttataagaca ggcgtgccct gtgaggcatg cccttcaaac      540

tgtgaagaca aactttgtac caacccttgc atttactacg atgaatactt cgactgtgat      600

attcaggtgc actatctggg ttgcaaccac tcaactacca tccttttttg caaggccacc      660

tgcctgtgcg acactgaaat aaag                                             684


<210>  4558
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  4558
ggacccagcc ccgacacttg ttcccaagac cttaatagta gagtcaagcc cggcttcccg       60

aaaaccataa agaccaacga tccaggggtc ctccaggctg cccgttattc cgtcgagaaa      120

tttaacaact gtaccaacga tatgttcctt ttcaaggaga gccggatcac aagggctctg      180

gtccaaatcg tgaaaggtct gaaatatatg ctggaagtcg agatcgggag gacaacatgt      240

aaaaaaaacc aacacctcag gctcgatgac tgtgattttc agactaatca caccctgaaa      300

cagaccctgt catgttactc tgaggtttgg gtagtgccat ggctgcagca cttcgaagtt      360

ccagttttac ggtgtcac                                                    378


<210>  4559
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4559
tggcggtttc aagaggaaga ggagtggaat gaccagaagc agatcgccgt gtatctccca       60

ccgacactgg aattcgcggt ctataccttt aataagcagt ccaaagattg gtacgcctac      120

aagcttgttc cggtgctggc ctcctggaag gagcagggct atgataagat gactttcagt      180

atgaatcttc agttaggcag gacgatgtgt ggcaagtttg aggacgacat tgacaactgc      240

ccgtttcagg agagtcctga attaaacaat acatgcacgt gtttttttac cattggtatt      300

gaaccctggc gcacgaggtt cgatttatgg aacaaaactt gtagtggtgg acactca         357


<210>  4560
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  4560
cgacggtttc agaggaacac aggggaaatg tctagcaatt ccactgcgct ggccctggtt       60

agaccaagca gcagcggact tatcaacagt aataccgata acaatttggc tgtttatgat      120

ctgagccgag atatcttgaa caattttcca cacagtatcg caaggcaaaa aaggatcctg      180

gtcaatctgt ccatggtgga aaataagctg gttgaactcg aacacacttt gctctcaaaa      240

ggatttcggg gcgcatctcc ccaccgaaaa tctaca                                276


<210>  4561
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  4561
atgtcccgga gggagggctc cctggaggac cctcagacag actcttctgt gagtttactt       60

ccacacttgg aagcgaagat cagacagacc cattcacttg cacaccttct tacaaaatac      120

gcggagcagc ttcttcaaga gtatgttcag ctgcaaggag atcccttcgg tttgcctagc      180

tttagtcctc ctaggctgcc cgttgccggg ctcagtgcac cagcgccttc ccatgccggt      240

ttacctgtcc acgaacgtct gcgattggat gcagccgctc tcgcagcttt gcctcccctt      300

cttgatgccg tttgtcggcg gcaagcagag ctgaaccccc gagcccctag gctgttgcgc      360

cgactggagg atgcagctag gcaggcccgg gctcttggag ccgccgtgga agcactcctg      420

gcagcccttg gtgctgcaaa ccgcggacca cgtgccgagc cgccagccgc aaccgcttct      480

gccgccagtg ctacgggcgt cttccctgcc aaggtccttg ggctgcgggt ttgtggactg      540

tatcgcgagt ggctcagcag aactgagggg gatctgggtc agctcctgcc tggcggctct      600

gca                                                                    603


<210>  4562
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  4562
gctccgccgg agtgggactg gagatctaaa ggcgcagtga caaaagtgaa ggatcagggg       60

atgtgtggct cttgctgggc tttctctgtg accggcaacg tggaaggaca gtggtttctt      120

aatcagggaa cactgctgag cctgtccgaa caggaattac ttgattgtga caagatggat      180

aaggcctgta tggggggctt accctcaaat gcctattctg ccatcaaaaa cctggggggc      240

ctcgagacag aagatgacta cagttaccag gggcatatgc agagctgcaa cttttccgca      300

gaaaaagcta aagtatatat caatgattca gtagagttat cccaaaacga gcaaaagctc      360

gccgcttggc tcgcaaaacg cggtcctatt tccgtggcta taaatgcctt cggcatgcag      420

ttctatcgtc acggcatttc tagacccttg cggccactgt gtagcccctg gctgattgac      480

cacgcagttc tgctcgtggg ttatggaaac agaagtgacg tccctttctg ggcaattaag      540

aactcctggg gcacagattg gggggagaag gggtattact acctccaccg agggtcaggt      600

gcatgcgggg tcaacacaat ggctagcagt gcggtcgtgg ac                         642


<210>  4563
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  4563
ttgccagact ctgtcgattg gagagagaag ggctgcgtga ccgaggtgaa gtatcaaggt       60

agctgtggtg catgctgggc ctttagcgca gtgggggctc tggaggctca gctgaagctc      120

aagacaggaa agctggtttc cctttctgcc cagaatttgg tagattgttc aacagagaag      180

tacgggaaca agggctgtaa cggcggtttc atgaccacag cctttcaata cattatcgac      240

aacaagggaa ttgatagcga cgcatcatac ccctacaagg ccatggacca gaaatgccag      300

tacgattcca agtatagggc cgccacttgc agcaagtaca ccgagctgcc atatggtcgg      360

gaagacgtgc ttaaggaggc cgttgctaat aagggaccag tttctgttgg tgtcgatgcg      420

aggcatccct cttttttcct gtatagatct ggggtttact atgaacctag ctgtacccag      480

aatgtgaatc acggagtact cgtagtgggc tacggcgacc tgaatgggaa ggaatactgg      540

ctggtcaaga attcttgggg acacaacttt ggagaggagg gatacattag aatggcacga      600

aataagggta atcactgtgg tattgcctcc tttccctctt acccggagat c               651


<210>  4564
<211>  747
<212>  DNA
<213>  Homo Sapiens

<400>  4564
gtcccattca gttgtgattg gcgaaaagtg gccagcgcca ttagtcccat caaagatcaa       60

aaaaattgta actgctgctg ggctatggcg gcggctggca atatcgagac actgtggcgg      120

atatcttttt gggacttcgt ggatgtatcc gtccaggagc tcctggactg cggacgatgt      180

ggggacggtt gccacggggg attcgtgtgg gatgctttca ttaccgttct gaataactcc      240

ggcctcgctt ccgagaaaga ttaccccttc cagggtaagg tgcgggctca ccggtgccac      300

cctaaaaagt atcagaaggt cgcctggatc caggatttta ttatgctcca gaacaatgag      360

catagaatcg cccagtacct cgctacctat ggcccaatca cagtgacaat caacatgaag      420

ccccttcagc tctaccgcaa gggtgtcatt aaagctactc ccactacctg cgacccacaa      480

ctcgtggatc actccgttct tctcgtaggg tttggcagcg tgaagtccga agaaggtata      540

tgggccgaga cagtgagcag tcagagtcag ccgcagcccc cacaccctac accgtactgg      600

attttgaaga atagttgggg cgctcaatgg ggggaaaagg ggtacttccg tctccatcgg      660

ggatcaaata catgcggaat aaccaagttt cctctcacgg cccgcgtgca gaaacctgat      720

atgaagcctc gcgtctcttg tccacca                                          747


<210>  4565
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  4565
cggctgctgc tgttgcccag ggtgttgttg actatggctt ccggaagtcc accgacccag       60

ccgagccctg catccgatag cgggtccgga tacgttcctg gatctgtgag cgcggctttt      120

gtgacctgcc ccaacgagaa ggtagcgaaa gaaatcgcac gggcggtagt ggagaagcgg      180

ctggcagctt gcgtcaatct gatcccgcaa attacctcca tctatgagtg gaagggcaag      240

atcgaggagg atagcgaggt gttgatgatg ataaaaacac aaagcagctt agtcccagca      300

ctgacggatt tcgtgaggag cgtgcatccc tatgaggttg cagaagtaat tgccctgcca      360

gtcgagcagg gcaacttccc atacctgcag tgggttaggc aagtaactga atcagtcagc      420

gatagcatca cagtcctgcc g                                                441


<210>  4566
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  4566
ctgcatcttg atgttcagag gggccgtagg gtctcaccag gatgtcctat agtcggtaca       60

catgtatgcc ccgtgagggt gcagcaggag atcgacgacg tgattggcca ggtgagaaga      120

cctgagatgg gcgatcaggc tcatatgccc tgtacgaccg cagtgatcca tgaggtgcag      180

catttcggcg acattgtgcc cctcggagtc acccacatga ccagtcgcga catcgaagtg      240

cagggcttcc gcatcccaaa gggcaccaca ctgattacta acctgagttc cgtcctgaaa      300

gatgaagccg tctggaagaa accattccgg ttccaccctg aacatttctt agacgcccag      360

ggccacttcg tgaagcctga ggcatttctt ccattcagcg ccggacgtcg cgcttgtctg      420

ggggaaccgt tagctaggat ggaactcttt ttgtttttta ccagcttact gcagcacttc      480

tctttctccg ttgctgccgg ccagccacgc ccatctcact ctcgcgtggt cagcttcctc      540

gttactcctt caccttatga attatgtgcc gtcccccga                             579


<210>  4567
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  4567
tatgacccag aggctgcctc cgccccagga tccggtaacc cctgtcatga agctagcgca       60

gcacagaaag aaaacgcagg ggaagatcca gggctggcca ggcaggctcc gaagccgaga      120

aagcagaggt cctcattgct ggagaagggg cttgatggag ccaagaaagc agtaggcggc      180

ctcggtaaac tggggaaaga tgcggtggag gacttggaga gcgtggggaa aggcgcagtc      240

catgacgtaa aagacgtgtt ggactccgtc ctc                                   273


<210>  4568
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  4568
aattggtacg tcaaaaaatg tttaaatgac gtgggaatct gcaaaaagaa gtgcaagcct       60

gaggaaatgc acgttaaaaa cggatgggcc atgtgcggca aacagagaga ctgctgtgtg      120

cccgcagata ggcgcgcaaa ttaccccgta ttttgcgtac agacgaagac cacccggatc      180

agcactgtca cggccacgac agcaacgacc actcttatga tgacaaccgc ttctatgtcc      240

tccatggctc ctacacccgt cagtcctact ggc                                   273


<210>  4569
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  4569
gcccggctta agaagtgttt taataaagtg acagggtatt gccgcaagaa gtgcaaagtg       60

ggcgagcggt atgagattgg atgtttgagc ggaaagctct gctgcgctaa cgacgaggaa      120

gaaaaaaagc atgtgtcatt caagaagccg catcagcact caggggaaaa actctcagtg      180

ctgcaggatt atattattct gccaaccatt acgattttca ccgtg                      225


<210>  4570
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  4570
tggaattacc tcttcgactt tcatccacac cgagtgctgg tggtaggggc cttcgcgaat       60

ttttgtacag aacccactgg ctgctcctgt ctgttcccta aactccctcc acacctctta      120

atgctcccat gctggtttca cctgcttttt tttcaagact atatcatgtc tggggctagc      180

gccctgccac caggtttggt gagcttcgtc aaagctccat tgccacagtg gtggcccggc      240

ggctgcccag gcgtcggcgg accactccag gctctggagg ccaaaccagg ccaactcagt      300

ctgccgatcc gcaaccaaaa gagactggtg aaatctgcac ttgaactggg ggaaaacgag      360

ctgtttcagc agtttccgaa ccctcagtca agctgggtgc agcgaacaca ggaagctctg      420

cgtccgttac tgtcagttgc gctgcagctg tttcttgggc gcagggggct ccctcttcct      480

tttagagcac cgattaggac cgttgtcgga agcgcaatcc ctgttcaaca gtccccgccc      540

ccttcccccg cgcaggtgga cacactgcag gcccggtatg tcgggagact tacacagctc      600

ttcgaggaac atcaagcccg gtacggcgta ccagccgacc gtcacctcgt gttgaccgag      660

gctagaccca ctgcctggcc cagactcagt gcggga                                696


<210>  4571
<211>  690
<212>  DNA
<213>  Homo Sapiens

<400>  4571
ctggtacaac agggccttaa ggtggtgggg tgcgccagaa ccgtggggaa tattgaggag       60

ttggccgccg aatgcaaatc tgcggggtat ccgggaacac tgatccctta tcggtgtgat      120

ctttctaatg aggaagacat tctgtcaatg ttcagtgcga ttagatcaca acatagcggc      180

gtggacattt gcatcaataa cgccggtctg gcacgcccgg atacactgtt gagtggaagc      240

acaagcgggt ggaaggacat gttcaacgta aatgtcctgg ccctgtctat ctgtacccgc      300

gaagcctatc agtcaatgaa ggaacgcaac gtcgacgacg gacatattat taatattaac      360

agtatgtccg gccatcgtgt gctgcccctt tctgtgacgc atttctactc agctaccaag      420

tatgcagtaa ctgcactgac ggaggggctg agacaagagc tgagggaggc tcaaacccac      480

atccgtgcta cgtgtatttc acctggagtg gtcgagaccc agtttgcttt caagctgcac      540

gataaggatc ccgagaaagc cgcggccact tatgaacaga tgaagtgtct caaacctgaa      600

gatgtcgccg aggcagtcat ttacgtgctt agtactccag cacacattca aatcggtgat      660

attcaaatgc ggccaactga acaggttaca                                       690


<210>  4572
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  4572
cccccttgtg ggggaatggg gaatctgcgg ggccgcacag ctgtagtcac aggcgctaac       60

tccgggattg gtaagatgac agccctggaa ctggcacggc gtggagctcg tgtggtcctc      120

gcttgcaggt ctcaggaacg gggggaggca gccgcgttcg accttcgtca ggaatccggc      180

aataacgaag tgatctttat ggcgttggat ctggcgtccc tcgcttccgt ccgtgccttc      240

gcgaccgcct ttctcagctc tgaacctcga cttgacatcc tgattcataa cgccggcatc      300

tcaagttgcg ggcgaaccag ggaggccttc aacctcttat taagggtcaa ccatatcggg      360

ccctttctct taactcatct gctgctgcct tgccttaaag cctgcgcccc atctcgtgta      420

gtcgttgttg catccgccgc gcactgtcgc ggccgattgg actttaaaag attggatcgt      480

cccgttgtgg gttggaggca agaactgcgg gcatacgccg acacaaagct ggccaatgtg      540

ttgttcgcgc gggaactggc taatcagctg gaagccacag gagtgacatg ctacgccgca      600

catcctgggc ctgtcaactc cgaactgttt ctgagacacg ttccggggtg gctgcggcct      660

cttctgcgac ccctggcctg gttggtactt agggctccaa gaggaggtgc tcagactcca      720

ctctattgtg ctcttcaaga gggcatcgag cctctctcag gccgctactt cgcaaactgc      780

catgtggagg aggtacctcc cgcagcaaga gatgacaggg ccgcgcacag gctctgggag      840

gcctctaaac gccttgcagg actcggcccg ggtgaagacg ccgaaccaga cgaagatcca      900

cagtctgagg attcagaagc accaagctca ctgagtaccc cacaccccga ggagccaaca      960

gtgtctcaac cctacccaag tccacagagc agtcccgact tgtccaagat gacccacagg     1020

attcaggcca aagtggagcc cgaaattcag ttgtcc                               1056


<210>  4573
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  4573
agaatgactc gacgggaccc cctgaccaat aaagtggcac tggttacagc gtcaacggat       60

ggcatcggct ttgccatcgc tagacgtctg gctcaagaca gagcccacgt cgtggtttcc      120

agccgcaagc agcaaaacgt ggatcaggcg gtggcgacgc ttcaaggaga aggcttaagt      180

gttacaggaa cagtgtgtca cgtcgggaag gccgaggaca gagagcgctt agtggccatg      240

gcagtgaagc tgcacggagg cattgatatc ctcgtttcta atgctgcagt gaatccgttc      300

tttggctcct tgatggatgt gaccgaggag gtctgggata agacccttga catcaatgtg      360

aaagcccccg cacttatgac aaaggcagta gtgccagaga tggagaaacg aggaggcgga      420

tctgtcgtaa ttgtctcctc aattgcagca ttctccccgt ctccagggtt ttccccttac      480

aacgtctcta agacagcgct cctcgggctt aataacaccc tcgcgatcga gctggcaccg      540

agaaatattc gggtgaattg tctgcacctg gacctgtcca ggctggctag cgctggctgc      600

agtggatgga ccaggaagaa acgcaaagca                                       630


<210>  4574
<211>  906
<212>  DNA
<213>  Homo Sapiens

<400>  4574
agaaaaggca agcttaagat cgaggatata accgacaagt acatcttcat taccggctgt       60

gactcagggt ttggaaattt ggcagcccga actttcgata aaaagggctt ccacgtaatc      120

gctgcttgcc tcaccgagtc tggatccacc gcactcaaag ccgagacgtc cgaacgactt      180

cggaccgtgc tgctggatgt tacagacccg gaaaacgtca agaggacagc ccagtgggtt      240

aagaatcagg tcggggagaa agggctctgg ggcctcataa ataatgccgg ggtccccggt      300

gtgttggccc ccaccgactg gctcacactg gaggactata gagaaccaat tgaagtcaac      360

ctgttcggcc tgatttctgt gactctgaat atgttgcctc tggtgaaaaa agcccaaggc      420

agagttatta acgtttcttc tgtggggggc cgcctggcga tagtcggagg ggggtacact      480

ccatctaaat atgccgttga aggcttcaat gattccctgc gccgagacat gaaggcgttc      540

ggcgtgcatg tctcatgtat tgagccaggg ttgtttaaga ctaacctggc agaccctgtg      600

aaagtgattg aaaaaaagtt agccatttgg gagcagctgt ccccagatat aaagcagcag      660

tacggagagg gatacattga aaagtctctc gacaaactga aaggtaataa atcttacgtc      720

aatatggacc tttcccccgt ggtggaatgt atggaccatg cacttacctc cctgtttcct      780

aagacccatt atgctgcggg gaaagatgct aagattttct ggatcccttt atcacacatg      840

cccgccgctc ttcaggactt tttactttta aagcagaagg ctgagctggc gaaccctaag      900

gcagtg                                                                 906


<210>  4575
<211>  1206
<212>  DNA
<213>  Homo Sapiens

<400>  4575
cttccagcct cttccctgag ctctcttgtg ccgcaagtgc gaacctctta taatttcggt       60

cggacgtttt tgggcttgga taaatgtaat gcctgcatcg gaacctctat atgcaagaaa      120

ttctttaagg aggaaatccg tagtgacaac tggctggcct ctcacctggg cctgccaccc      180

gatagcttat tatcctaccc cgcgaactac tccgacgaca gcaagatttg gaggccagtt      240

gaaatcttta gactggtttc aaagtatcag aacgagatca gtgatcggag gatctgcgcc      300

agtgcctctg ccccgaagac atgctccatc gaaagagttc tccgaaagac tgagcggttc      360

cagaagtggc tccaagccaa gagactgact cccgatttgg tgcagggact tgcctcaccc      420

ctgttgaggt gtccttccca gcgacttctt gaccgtgtcg tgagaaggta tgctgaggtt      480

gctgatgcgg gaagtatctt tatggaccac ttcacagacc gagataaact gcggctgctt      540

tataccctgg ctgtaaatag ccaccctatc ctcctgcaga tctttccagg cgctgagggc      600

tggccactgc caaagtactt gggctcatgt ggtagatttc tcgtttccac gtccacccgg      660

ccccttcaag aattctacga tgctccgccc gatcaggccg ccgatttagc ctaccagctt      720

ctcggtgtcc tggaatccct ccgcagcaac gacctgaatt acttttttta tttcactcat      780

attgacgcag ggatgttcgg agtcttcaac aacggtcact tgttcatccg cgatgcatct      840

gccgtcggag tgatcgacaa gcaggaggga tctcaggagg ctaatagagc gggagaaaac      900

aaggacatct tttcctgcct ggtgagtggc tgtcaagccc agctgccctc ttgcgaaagc      960

atctcagaga agcagagctt ggtcttagtg tgtcagaagt tacttcctag gctgttgcag     1020

ggccggttcc caagtcccgt gcaggacgac atcgatagca ttctggtgca atgcggggat     1080

tccattcggc ctgatccaga agtcctgggc gcggcaagcc agcttaaaga tatcttaagg     1140

cccttgcgga cgtgcgattc ccgcttcgcc tatcgctacc cagattgtaa gtataacgac     1200

aaattt                                                                1206


<210>  4576
<211>  1293
<212>  DNA
<213>  Homo Sapiens

<400>  4576
gcttacacta cccccgggcc cccacgggca ctcacaaccc tcggcgcccc acgggcacac       60

acaatgcctg ggacttatgc tccgagtacc accctcagca gcccttccac ccagggcttg      120

caggaacagg ctcgggcgct catgagagat ttccctctcg tggacgggca caatgacctg      180

ccccttgtgc tgagacaagt gtaccagaag gggcttcagg acgtcaacct ccgcaacttt      240

tcttatgggc agacatcatt agaccgcctg cgcgacggtc tggtgggcgc ccagttctgg      300

agcgcgtatg tcccgtgcca gacacaggac cgtgatgccc tcagacttac attggagcaa      360

attgatctga tccgacgcat gtgcgcaagc tatagcgaat tggaacttgt cacctccgca      420

aaagctctga atgatacgca aaagctggcc tgcctcatag gtgtggaagg cgggcactca      480

ttggacaaca gcctgtcaat tttacggact ttttacatgc tcggagtgcg ctatctgact      540

ttaacgcaca cttgtaatac cccttgggct gagtcatcag ccaagggagt acactctttc      600

tacaacaata tcagcggact gacagacttc ggcgaaaagg tagtggctga aatgaaccgc      660

ctgggcatga tggttgatct ttctcacgtt agtgatgccg tggcgcggag ggccctggaa      720

gttagccagg ctccggtgat cttctcccat agcgcggctc ggggagtgtg taattccgca      780

agaaatgtcc cagacgacat tctgcaactt ctcaagaaga acggcggcgt tgttatggtc      840

tcattatcta tgggagtcat ccagtgcaac ccctccgcaa acgtatccac cgtggccgac      900

cactttgacc acatcaaggc cgtgatcggc tcaaagttta tcggtattgg gggtgactat      960

gatggtgctg ggaaatttcc ccaggggctt gaggatgtca gcacctaccc cgtgttgatt     1020

gaagaattac tttctcgggg gtggtccgag gaggaactcc agggggtact tcgagggaat     1080

ctcctcagag tctttagaca agtagagaaa gtccaagaag aaaacaagtg gcagagtcca     1140

ctggaagaca agttcccaga tgagcaactc tcaagcagct gccactcaga tttaagccga     1200

ctccgtcagc ggcagagcct gacgtctggc caagagttaa ccgagattcc catccattgg     1260

acagcaaaac tgcccgcaaa gtggagtgtg agt                                  1293


<210>  4577
<211>  972
<212>  DNA
<213>  Homo Sapiens

<400>  4577
ggtgcgctgg cacctggaac accggcacgc aatctgcctg agaatcacat tgatctgcct       60

gggcctgctc tgtggacccc tcaggcttcc caccatcgga gacgcgggcc tggtaagaaa      120

gagtggggtc ctggtctgcc atcccaagcc caagatggcg cagtggtgac cgccactaga      180

caggcctccc gcctgcctga ggcggagggt ctgctgcccg agcagtcccc tgccgggttg      240

ctgcaggaca aagacctgct cctcggcctg gctctgcctt atccagagaa ggagaatcga      300

ccccctggct gggagaggac aagaaagagg agccgcgaac acaaacggcg gcgagaccgc      360

ttgaggctgc atcaggggcg cgcccttgtg cgaggccctt ccagcctgat gaaaaaggct      420

gagctgagtg aggcccaggt gctggatgct gcaatggaag agagcagtac ctctcttgcc      480

ccgactatgt ttttcctgac tacctttgag gccgcaccag ccacagaaga atctctgatt      540

ttgccagtta cgagtcttcg tcctcagcag gctcagcccc ggagcgacgg ggaggtcatg      600

cccacgctgg atatggcact tttcgactgg acggattatg aggacctgaa gcccgatggc      660

tggccatcag cgaagaagaa ggagaaacat cggggcaaac tcagttctga cgggaatgag      720

acctcacccg ctgaaggaga gccttgtgat caccatcagg actgtcttcc cggcacctgc      780

tgcgatttaa gagaacactt gtgcacaccc cataatcggg gcctgaacaa caaatgcttc      840

gatgattgca tgtgcgtcga aggtctgagg tgttacgcga aattccaccg gaatagacga      900

gttacccgca gaaaaggacg ctgtgtggaa ccagaaacag caaacggcga ccaaggaagc      960

ttcattaatg tg                                                          972


<210>  4578
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  4578
ctggttaata ataagggcag cgcaaattca tccattgtga tccaactgag tactaacgat       60

ggcgagtgcg tgacggttaa acccggaact ccgagccccg cctgcccacc gactatgacc      120

acgacctcta ctgtccctgc aagtaccgca actgaatcca ctacctccac cgctacagcc      180

gctacaacat ccactgagcc aatcacagta gcaccaactg accatttg                   228


<210>  4579
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  4579
ctgagacatg tcgtctactg gaattcaagt aatccaaggc tgctccgggg tgatgctgtt       60

gtggaactgg gacttaacga ctacctggac attgtctgtc cgcattatga gggccctggc      120

cctcctgagg gacctgagac ttttgcgctc tacatggtgg attggcctgg atatgaaagc      180

tgtcaggcag agggtcctag ggcatacaag cgctgggtgt gcagcctgcc ctttgggcat      240

gtccaattta gcgagaaaat tcagaggttc acacccttct cccttggttt cgagtttctg      300

ccgggtgaga cttattatta catctctgtg cctaccccgg agagctccgg ccagtgtttg      360

cggctgcaag tgtctgtctg ttgtaaggag aggaaatctg aatccgccca ccccgttgga      420

agccccgggg aaagt                                                       435


<210>  4580
<211>  1437
<212>  DNA
<213>  Homo Sapiens

<400>  4580
cgcctggtcg gagaggaaga agccggcttt ggtgagtgtg acaaattttt ctatgccgga       60

accccaccgg ctggtttggc ggcagattct catgtgaaaa tttgccagcg ggcagagggc      120

gccgagaggt ttgccacgct gtacagtacc cgggaccgaa tccccgtgta tagtgcgttc      180

cgtgccccaa gaccagcgcc tggtggtgca gagcagcggt ggctggtgga gcctcaaatc      240

gacgatccca acagtaatct cgaagaagcc ataaacgaag ccgaggccat cactagcgtg      300

aactcactcg gctctaagca ggctctgaat actgattacc tcgacagcga ctaccagaga      360

ggacagctgt atccattttc cctctcctct gacgttcagg tggctacttt tacgttaacc      420

aattctgctc caatgaccca gtcctttcag gagaggtggt acgtgaactt gcactcattg      480

atggacagag ccttaactcc ccaatgcggc agtggcgaag acctctatat cctcacaggg      540

acagtcccca gtgattatag agtcaaggac aaggtcgccg tccccgaatt cgtgtggtta      600

gcagcctgtt gcgcggttcc aggagggggg tgggctatgg ggtttgtgaa gcataccaga      660

gactcagata taattgaaga cgtgatggta aaggatctgc agaagctgct gcccttcaat      720

ccccagctgt ttcagaacaa ctgcggggag accgagcaag acactgaaaa gatgaaaaag      780

atcttagagg tggttaatca gatccaagat gaggaaagga tggtccagtc ccagaagtct      840

agctcacccc tgtcaagcac ccgtagcaaa aggagcacct tgctcccccc cgaggcctcc      900

gagggctctt caagcttcct gggaaaatta atggggttca ttgccacccc cttcataaag      960

cttttccaac tgatctatta tcttgtggtg gctatcctga aaaatatcgt gtattttttg     1020

tggtgtgtta ccaaacaggt tattaatggt attgaatcct gtctctacag gctcggcagc     1080

gcaacaatct catattttat ggccattggg gaggagttgg tgtctattcc ttggaaagtg     1140

ttgaaggtcg tggccaaagt gattcgcgca ctgttgcgga ttctttgttg cttgcttaaa     1200

gcaatctgcc gggtgctcag catccccgtt cgagtgcttg tggatgtcgc gactttccct     1260

gtgtacacta tgggagccat tccaattgtc tgcaaggaca tcgctctcgg cctgggcggc     1320

acagtcagtc tgctgtttga caccgcattt ggcaccctcg ggggcctctt tcaggtagtg     1380

ttctcagttt gcaagaggat aggctacaag gttacttttg acaattccgg cgaactc        1437


<210>  4581
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  4581
ggtaaaattg agagttgcgc ctctaggtgc aatgagaagt tcaatcgcga tgccgcttgt       60

caatgtgatc ggagatgctt gtggcatgga aactgttgtg aggactacga acacctgtgt      120

accgaggatc acaaagaaag cgaacccctg cctcagctcg aggaggagac cgaagaagct      180

ctcgctagca acttatattc cgctcctacc tcctgtcagg gtcgctgtta tgaggccttt      240

gataagcatc accagtgcca ctgcaacgcc cgctgtcagg agttcggcaa ttgctgtaag      300

gatttcgagt ctctctgctc agatcatgag gtgagccact cctccgacgc cattaccaag      360

gaggaaatcc agtccatctc tgagaagatt tatagagcgg acaccaacaa agcccagaaa      420

gaggatatag tgttgaactc ccaaaactgt atatcccctt cagagactcg caatcaagtg      480

gaccgttgcc caaaaccact ctttacatac gtgaacgaga aactgttttc caagccgacc      540

tacgccgctt ttatcaactt gctcaacaac taccaaaggg ccacggggca cggtgaacat      600

ttttctgccc aggaattagc cgagcaggat gcattcctca gagagattat gaagaccgca      660

gtaatgaagg agttgtatag ttttctccac caccagaacc gatacggttc tgagcaagaa      720

tttgtggacg atctgaagaa tatgtggttc ggcttgtact cccggggcaa tgaggaggga      780

gatagctccg gtttcgaaca cgtcttcagc ggcgaggtaa agaaggggaa ggtcacgggc      840

ttccataatt ggattagatt ctatcttgag gaaaaggagg ggctggtcga ctattactct      900

cacatctacg acggcccctg ggatagttat ccggacgtgc tcgccatgca atttaactgg      960

gacggctact acaaagaagt gggtagcgct ttcatcggca gtagtccaga atttgagttt     1020

gcattgtaca gtctgtgttt tatcgccaga ccaggtaaag tctgccagct gagccttgga     1080

ggatacccac tggccgtgcg gacctataca tgggacaagt ccacgtatgg caatggtaaa     1140

aaatatatcg ctactgcata tatagtctcc agtacc                               1176


<210>  4582
<211>  1530
<212>  DNA
<213>  Homo Sapiens

<400>  4582
ggccaaaatg aggcccctcc gaacactcac agcattccag gcgaaccttt atataattat       60

gcgtccattc gtttaccaga ggagcatatc cctttctttc tgcataacaa taggcacata      120

gcaacagtgt gtcggaagga ctctctttgt ccctacaaaa aacatctgga gaagctcaaa      180

tactgctggg gttatgagaa atcctgtaag ccagagttcc ggtttggcta ccccgtgtgc      240

agctatgtag acatggggtg gaccgacacc ttggagtcag cggaagatat tttttggaaa      300

caggccgatt tcgggtacgc ccgcgaacgg ctcgaagaga tgcatgtgct ctgccagcca      360

aaggaaacct ccgactcttc tctcgtctgc agccgctatc tgcagtattg tagagccacg      420

aatctgtatc tggatctgcg caatataaag aggaaccacg atcggtttaa ggaagacttc      480

tttcagtccg gggaaatcgg cgggcactgc aagctggata ttcggaccct gaccagcgag      540

ggccagagaa agtctccact gcagtcctgg ttcgccgaac tgcaaagcta cactcagctt      600

aattttcgcc ccattgagga cgctaagtgc gacatcgtga ttgagaaacc aacttacttc      660

atgaaactgg atgccggagt gaacatgtat caccactttt gtgatttcat taacctctac      720

atcacacagc atgtcaacaa tagtttcagc acggacgtgt acattgtcat gtgggatacc      780

tctagttacg gctacggtga cttgttttca gacacctgga atgctttcac agactatgat      840

gtgattcacc ttaagacgta cgacagcaag agggtgtgtt ttaaagaggc tgttttttca      900

ttgttgccac gaatgaggta tggacttttc tacaatacac ccctcatttc cggatgccaa      960

aacaccgggc tgtttcgggc ctttgctcaa cacgtcttgc atcgattgaa tataacccag     1020

gagggaccta aggacggtaa gataagagtc actatccttg cccggagtac agagtaccgg     1080

aaaatcctta accagaacga actggtcaac gccctgaaaa ccgtcagtac cttcgaagtc     1140

cagatcgtgg actataagta tcgggagctg ggatttctcg accaactccg catcacacat     1200

aatactgata ttttcatcgg catgcacggg gcgggcctga cccacctgct cttcctcccg     1260

gattgggcgg cagtgttcga attgtataat tgcgaagatg aacgctgtta ccttgacctg     1320

gccaggttgc gcggcgtcca ttatatcact tggagacgac agaataaggt ttttccacag     1380

gataaaggcc accatccgac cctgggtgaa catcctaagt ttactaacta cagttttgat     1440

gtggaagagt ttatgtactt ggttttgcag gcagcagatc acgtgctgca gcaccccaag     1500

tggcccttta aaaagaagca tgatgagctt                                      1530


<210>  4583
<211>  1083
<212>  DNA
<213>  Homo Sapiens

<400>  4583
aactccctgc tgacagaacc acccttcaga tggcggttct acctccatga aacttggacc       60

cagggcaacc gactcagcac cgtcacattg gctaccgttg attgccagcc tcacggctgt      120

caggctcagg tgacattcaa cttcacatca ttcaaatctg ttttacgggg ctggtccaat      180

ccgactatct gcttcgttta tgaccagacc cactccaact gccgagacta ctgggtggac      240

accaacggtg ggtgtccata tgcctattgc cgtatgcacg tcacccagct gcatactgct      300

aaaaaactgc agcacaccta taggctcact agtgatggcc gcaccaccta tttcctgacg      360

atccccgacc cttgggactc ccggtgggta agcggagtta ccgggcgctt gtataggtgg      420

cctacagact cctacccagt gggaaagctg cggatatttc tcacctacat ccgcgtaatc      480

cctcaggtgc ttagtaatct gaaggatcag gccgacaata ttaagcatca ggaggaggtc      540

atcaacacgc tcgtccaatc ccatccgaag gccgatatgg tgacttatga cgataaggca      600

gaggcgggtc ccttcagctg gattactctg gttaggcatg gcgcccggct ggtgaatatg      660

gctggacttg tgaacctgag tcactgtttt ctctgtaccg cactgagtca gcccccattg      720

gtggccgtgc ctctgcccca ggccttcaat acaagcggaa atcatactgc tcaccccagc      780

ggggtgttct ctgaacaggt gcctctgttc agggatccac tccaaccaca attcccattt      840

tgttacacca cacctaatag ctcttggtgc aatcagacat attccggctc cttaagcaac      900

ttgagcgctc cagcaggggg ttacttctgg tgcaacttca cccttacaaa acatctgaac      960

atttccagca ataatacttt gagccggaat ctgtgccttc cgatttcctt agtccccaga     1020

ctcacattgt actccgaggc agaattgtca tccctcgtca accctccaat gcggcaaaaa     1080

aga                                                                   1083


<210>  4584
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4584
gcccccccct cctgcaggga gtgttaccag agtctccatt accgggggga aatgcagcaa       60

tatttcacct atcataccca cattgaaagg tcctgctatg gtaacctgat tgaggaatgc      120

gtcgagagcg ggaagtcata ttacaaggta aaaaacttgg gggtctgcgg gtcccgcaac      180

ggggccatat gcccacgcgg gaagcagtgg ctttgtttca ccaagattgg gcagtgggga      240

gtcaacaccc aggtgttaga ggatatcaag cgagagcaga tcatagctaa agccaaggct      300

agtaaaccca ctacacctcc cgagaatagg cctagacact ttcacagttt catccagaag      360

ctg                                                                    363


<210>  4585
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  4585
atggtaacgc ccgtcacctg gatggataat cccatcgaag tctatgtcaa cgatagcgtt       60

tgggttcctg ggcccactga tgataggtgt cccgctaaac ctgaagaaga gggaatgatg      120

attaatatat ctatcggata ccactatcct cccatttgcc tgggcagggc ccccggttgt      180

ctgatgccag cagtgcagaa ctggttggtc gaggtgccta ccgtgtcccc aaactcccgg      240

ttcacctatc acatggttag cggtatgagc cttagaccaa gggtgaattg tctgcaggac      300

ttctcctatc agcgaagcct taaattccga cctaagggca aaacctgtcc gaaagagatt      360

cctaaagggt ccaaaaatac agaagttctg gtctgggaag agtgcgtggc gaactctgtc      420

gtaatcctgc aaaacaacga gtttggtact atcatcgact gggcaccaag aggtcagttt      480

taccacaatt gttccggaca gacgcagagc tgcccaagcg cacaggtcag cccagccgtc      540

gacagcgatc ttacagaaag tctcgataaa cacaagcaca aaaaactcca atcattttac      600

ctctgggagt gggaagaaaa aggaatatcc accccacgtc caaaaattat ttctccggtg      660

agcgggccag agcaccctga gctctggcgc ctgactgtgg catctcatca catacgaata      720

tggtccggca atcaaacact ggagaccaga tatcgtaaac ccttctatac tatcgatttg      780

aatagtattc tgactgtccc cctccagagc tgcgtgaagc caccttatat gttagtcgtg      840

gggaacatcg tcatcaagcc tgcaagtcaa actataacct gtgaaaactg caggctgttc      900

acctgcattg acagcacgtt caactggcaa caccgaatcc tgctggtgag ggccagggaa      960

ggcatgtgga tcccagtttc cacagaccgg ccctgggagg catcccccag tatccacatt     1020

ctgaccgaaa tccttaaagg cgtcctgaac cggagtaaac gg                        1062


<210>  4586
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  4586
atggtgaccc cagtcacctg gatggataat cctatcgagg tttacgtgaa cgactccgag       60

tgggttccgg gcccaaccga cgaccgttgt cccgctaaac ctgaggagga gggcatgatg      120

ataaatattt ctatcggata tcggtatcca cccatctgtc tcggtaccgc tccaggatgt      180

ctgatgcccg ctgtacagaa ttggctggta gaagtgccca tagtaagccc aatctctcgt      240

ttcacttatc atatggtctc tgggatgtct ttgcgcccca gagtgaacta tctgcaggac      300

tttccatacc agagatcact gaaatttcgg cctaaaggaa agccttgtcc caaagaaatt      360

cccaaggaat caaagaacac cgaagtgctg gtttgggagg aatgcgtcgc caacagcgcc      420

gttatactgc agaacaatga gttcgggaca atcatcgact gggcaccaag ggggcagttt      480

tatcacaatt gcagtggcca aacacagagc tgtccgtctg cccaggtctc tccagccgtg      540

gatagtgatc tgacagaatc cttagataaa cataagcaca agaaacttca gagcttttat      600

ccttgggagt ggggagagaa gggcatctca accccacgac ccaaaatcat ttcccccgta      660

tccgggccag agcatcccga gctctggagg ctgaccgtgg ctagccatca catccgtatc      720

tggagtggaa accagacatt agagactaga gacaggaaac ctttttatac tgtggacctc      780

aactcctcac tgacgctgcc actccaatct tgtgtgaaac cgccatacat gcttgtggtg      840

ggaaatatcg tgataaagcc cgacagccag actatcacgt gcgaaaattg tcgcctgctc      900

acctgtatcg attccacctt taattggcag catcggatct tgctcgtgcg ggccagagag      960

ggagtctgga tcctggtgag catggacaga ccatgggagg caagtcccag cgtccatatc     1020

ctgaccgagg ttctcaaggg cgtgctgaac cgatctaagc gc                        1062


<210>  4587
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  4587
atggtgacac ccgtaacatg gatggacaat cctattgaaa tctatgttaa cgactctgtt       60

tgggtaccag ggcctattga cgacagatgc cccgcaaagc cggaagaaga aggaatgatg      120

attaatatct caattggtta tcgttaccca ccaatttgct tgggccgcgc accagggtgc      180

ttgatgccgg ccgtccaaaa ttggcttgtt gaggtcccta ccgtgtctcc aatttcccga      240

tttacatatc acatggtctc agggatgagc ctgcgcccaa gggtgaatta tttgcaggat      300

ttttcctatc agagatccct caaatttagg cccaagggaa aaccctgtcc caaagagata      360

ccgaaggagt ccaagaatac cgaggtgctt gtctgggaag aatgcgtcgc aaatagcgcg      420

gtaattttac aaaacaacga gttcggtaca atcatcgatt gggcaccaag aggccaattt      480

taccacaatt gtagcgggca gacccagtcc tgtccttctg cccaggtgtc ccccgccgtg      540

gacagtgacc tcaccgagag tctcgataag cacaaacaca agaaactgca gagcttctat      600

ccttgggaat ggggcgagaa gagaatctct acacctagac ctaaaatcgt ctctcctgtg      660

agcgggcccg agcatccgga gttgtggcga ctgactgtgg caagtcacca tatccgaatc      720

tggtcaggca atcagacctt ggagacgcgg gactgcaaac ctttctacac tatcgacctg      780

aactcctccc ttacggtgcc gttgcagtcc tgtgtaaagc caccctatat gctggtggta      840

ggtaatatcg tgataaagcc tgatagtcaa accatcactt gtgagaattg ccggctgctg      900

tcatgtatcg attcaacatt taattggcag cacaggatcc tgcttgtccg ggcccgggag      960

ggcgtatgga taccggtgtc tatggatagg ccttgggaag cttccccctc agtgcatatc     1020

ctcaccgaag tactgaaagg cgtgcttaac cgctcaaagc gc                        1062


<210>  4588
<211>  867
<212>  DNA
<213>  Homo Sapiens

<400>  4588
atgtggaccg tgccaagctt tacgaatgat agttaccaag tgtataatgt gtttagcaca       60

aatagtttcc agctccttac cgtaaaacgc acaccccacg aagcctggcg ggttccctta      120

accaccaaaa ctaacaaaac aaaaggactg cccgattgtc ctaaaaagcc cactaacggg      180

ccatttatcg tgacctcaat attgtgggat aattgtaatg cccctaaggc agtcgtgctt      240

caaaccctcg ccatgggcat cgtgatcgac tgggctccta agggacacta ctggcaggat      300

tgcagtagca agaataccct gtgctcagag ttcatatata gcctggacta tattgaacat      360

gggtggcagt cctacactat gaggcagaga gttagtccat acccgttcaa gtggatggat      420

accggtatag ctccacccag accaaagatc atccacccat tcttcactcc agaacaccct      480

gaattatgga agttagctgc cgctctgtct ggtataaaaa tatggaacac cacatatcag      540

ttgctgagaa ccaagactaa gaccccaact ttcaacatca ccctcatctc cgagtgggtc      600

attcctatac gctcttgtgt gaaaccaccc tacatgttac tggtcggcaa tatcatcatg      660

atgccagatg cccagactat cgaatgccac aactgtaagc tctttacttg tatcgacgct      720

accttcaatc ctactacaag catacttctc gtacgagcac gcgaaggtgt ctggatccca      780

gtctccctcc accgaccatg ggagagcagc ccatccattc acattgtgaa tgaggtgctt      840

aaagatatcc tgaaaaggac taagcgg                                          867


<210>  4589
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  4589
cagtggaacg agaatagcct tgtgagcttc tctaagatta tcgcctccgg gaaccacctg       60

agcaactgct ggatttgtca taactttatt acccggtcat cttcatacca atacattctg      120

gtccgcaact tctccctcaa cctcacattc ggtagtggga ttcccgaggg ccagcacaaa      180

agcgtgcctc tgcaagtatc acttgccaac tctgcccatc aggtgccatg cctcgatttg      240

accccccctt tcaatcaatc aagcaaaacg agcttttact tctacaactg ttccagtctg      300

aatcaaactt gttgtccctg cccagagggt cactgcgaca gaaaaaatac atcagaagag      360

ggtttcccct caccaaccat acatccgatg agctttagcc cagcagggtg tcatcctaat      420

ttgacccact ggtgtccggc caaacagatg aatgattatc gagataagag cccacagaat      480

agatgcgcgg cctgggaggg caaagaactg attacctgga gggtgctgta cctgttgcca      540

aaggcccata cagtcccaac ttggcctaag tccactgtac cattgggagg acctttatct      600

cccgcctgca accaaacaat ccccgccggt tggaagagcc aactgcataa atggtttgat      660

tctcacatac cccgttgggc ctgcactccg ccgggatatg tattcctttg cggacctcag      720

aaaaataaat tgcccttcga cggctcccct aagattacat acagcactcc acctgtagca      780

aacttataca cttgtataaa taacatccag cacacgggag agtgcgccgt ggggcttctc      840

ggcccgcgcg gcatcggcgt aaccatttac aataccaccc aaccccgaca gaagcgtgca      900


<210>  4590
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  4590
caatggaacg aaaactctct ggttagcttt tcaaagatca tcgcttcagg aaatcatctg       60

agcaactgct ggatttgcca taatttcata acaagaagta gcagctatca gtatatcctg      120

gtgcggaatt tttcactcaa cctgaccttt ggaagcggaa ttcccgaagg tcagcacaaa      180

agcgtgccct tacaggtttc cctggcaaat tctgcccacc aggtgccttg cctcgacctg      240

acacctccgt ttaatcagag ttcaaaaaca tctttctact tctacaattg ctcctctctc      300

aaccagacct gttgtccctg cccagagggt cattgcgatc gcaagaacac gagcgaagag      360

gggtttcctt ctcccacaat tcacccaatg agtttcagtc cagcgggttg tcacccaaat      420

ttaacacatt ggtgtcctgc caagcagatg aatgactata gggataagtc cccgcagaat      480

cgatgcgcgg cctgggaagg taaggagctg ataacgtgga gggtgctgta ctctctccct      540

aaggcccaca cagtcccaac gtggccaaaa agtacagtgc cactcggtgg cccactcagt      600

cctgcctgca accagacaat tccagcagga tggaagagtc agcttcataa gtggtttgac      660

agccacatac cacgctgggc ctgcacaccg cctggatacg tttttctttg tgggcctcag      720

aaaaataagc tcccattcga tgggtcacca aagatcacgt atagtacacc gccagtcgcg      780

aatctttata cctgcatcaa caacattcag cacacaggcg agtgtgccgt tggcctgtta      840

ggaccgaggg gcataggcgt gaccatatac aatacgactc agccacgtca gaagagggct      900


<210>  4591
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  4591
aattacacca gactgtgggc taactcaaca agttcttggg actctgtaat ccagaataag       60

acaggtagaa atcaaaatga aaacattaat accaatccca taaccccaga ggtggactac      120

aaaggcaact ctacaaatat gccagaaacc tctcatattg tggcactgac tagtaagagc      180

gagcaggagc tctacatccc ctcagttgta agtaactccc ccagtaccgt ccagtccatt      240

gagaacacct caaagtctca cggagagatc ttcaagaaag acgtgtgtgc ggagaacaac      300

aacaacatg                                                              309


<210>  4592
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  4592
gtgccgcggt tccccaggac agaggtcgga gcaggacatt ccgtaaacga ggagaccaag       60

gcagaaaagg taggcaatca gactagcgtt atcccagcta caagcaggca ggcagcgctt      120

ggcaccagtt ggactcagcg ccgaacacaa cccttacagg agcggagcca ctggcaccct      180

cggggcaata acgccagtgg aatggggggc catcgcatgt ttccgggccc cttacgtggg      240

cccgcggctc aggttctgga gaacgagtgt ggctctctcg ggagagctgc agaaggccgg      300

tct                                                                    303


<210>  4593
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  4593
cccggagcca atcctacatt tcagacggga tatacacctg gcactcccta caaggtgtct       60

tgttcaccca ccagcggcgc tgtgccacca tattcttctt ctccaaaccc ataccaaacc      120

gccgtgtatc ctgttcggag cgcctatccc cagcagagcc cctacgcgca gcagggcaca      180

tattatactc aacctcttta tgctgcccct cctcatgtta ttcatcacac caccgttgtt      240

cagcctaacg gaatgcctgc gaccgtctac cccgccccca ttcctccccc cagaggaaat      300


<210>  4594
<211>  267
<212>  DNA
<213>  Homo Sapiens

<400>  4594
acctgcgaga ttgtaacact ggatcgcgac agttcacagc caaggcgaac cattgccagg       60

cagacagcac gctgtgcctg ccggaaggga cagatcgcgg gaaccacacg tgccaggcca      120

gcctgtgtcg acgccagaat tattaaaaca aaacagtggt gcgacatgct gccctgtctc      180

gagggggagg ggtgtgatct cttgattaac cggtcagggt ggacttgcac acagcccgga      240

ggacgaatca agacaaccac cgtgagc                                          267


<210>  4595
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  4595
ttatatttca aagtcgctaa agccctcaaa gccgcaaaag atcctgatgc cgtcgccgtt       60

aaaaatcaca atccagacaa ggtttgctgg gcaaccaaca gtcaggccaa ggccacgaca      120

atggagagct gtccttctct gcagtgttgt gaaggctgca ggatgcatgc ctcatctgat      180

agcctccccc catgctgctg cgacatcaat gaaggcctg                             219


<210>  4596
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  4596
tttcctcgca ttcagcagtt atttactagt ccggagtcct ctgtaaccgc tgctccccgc       60

gctcgcaagt ataagtgtgg gctcccccag ccatgtccag aggaacatct ggcattccgg      120

gttgtctccg gagccgcaaa tgtgatcgga cctaagatct gcctcgaaga caagatgctt      180

atgagcagtg tgaaggataa cgtaggtaga ggactcaaca ttgcattagt aaatggggtc      240

agtggtgagc tcatcgaggc gcgcgctttt gacatgtggg ccggggacgt caatgacctg      300

ctgaaattca ttagaccatt gcacgagggg acattggtgt ttgtggcgtc ctacgatgat      360

cccgccacaa aaatgaacga agagaccagg aagttgttct ccgagttggg cagcagaaac      420

gctaaagaac ttgcttttcg cgactcctgg gtatttgttg gcgccaaggg tgtgcagaat      480

aaaagtcctt ttgaacaaca cgtgaagaat tctaagcaca gcaataagta tgaggggtgg      540

cccgaagcct tggaaatgga gggttgcatc ccgaggagat ccaccgcaag t               591


<210>  4597
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  4597
cttcaagcgg ccgatacgtg tccagaagtg aagatggtgg gcctggaggg cagtgataaa       60

ctcactatat tacgtggttg cccggggctc ccgggcgccc caggaccaaa aggagaagct      120

ggaaccaacg gtaaaagggg ggagcgcggt ccccctgggc cacccgggaa ggccggaccc      180

cccggaccca acggggcccc aggcgagcct cagccatgtt taacagggcc tagaacatgt      240

aaggacttgc ttgaccgggg gcactttctg tccggttggc acacaattta tctgccagac      300

tgtcggccct tgaccgtgtt gtgtgacatg gacactgacg ggggcggctg gactgtcttc      360

cagaggcggg tcgacggttc cgtggacttc tatcgcgact gggcaactta caaacaggga      420

ttcggatctc gactcggaga attttggtta ggcaacgata acatacatgc cctcacagcc      480

cagggcacat ctgagctcag agttgacctg gtcgactttg aggacaacta tcaattcgca      540

aagtatcgtt cattcaaagt ggctgatgaa gccgagaagt ataacctcgt actgggggcc      600

tttgtggagg ggagtgccgg tgattccctc accttccaca acaaccaaag cttctctact      660

aaagaccagg ataacgattt gaatacgggg aattgtgctg tgatgttcca gggagcctgg      720

tggtacaaga actgtcacgt gtcaaacctg aatgggaggt acttgagagg cacacacggt      780

tccttcgcca atgggattaa ttggaaaagt ggtaagggtt acaattactc ctacaaggtg      840

agcgaaatga aagtacgccc tgcc                                             864


<210>  4598
<211>  1101
<212>  DNA
<213>  Homo Sapiens

<400>  4598
tgtggggcca tgagtccacc ccagttggca ctcaacccat ctgcactcct gtctagggga       60

tgcaatgatt cagacgtttt ggccgtggct ggcttcgcct tgcgggacat taataaggac      120

cgaaaggacg gatatgtgct ccgcctcaat cgggtgaatg acgcacagga atacaggcgc      180

ggcgggctgg gaagcctctt ttatctgact ctcgacgtcc tggagactga ctgtcacgtt      240

cttaggaaaa aggcatggca ggactgcggg atgaggattt tctttgagtc tgtatacggt      300

cagtgtaaag ccatctttta catgaataat ccatctagag tgctctacct ggccgcatac      360

aactgtacac tccgccccgt ttctaaaaaa aagatctata tgacctgtcc agactgtcct      420

tccagcattc ctacagactc ttccaatcac caggtcttag aagcagctac tgagtctctc      480

gccaagtata ataacgaaaa cacttcaaag cagtacagtt tgtttaaggt aacgcgcgcc      540

tcctcccaat gggttgtggg gccgtcttac ttcgtggaat accttatcaa agaatcaccc      600

tgcacgaagt cccaggcctc aagttgctca ctgcagagct ccgattctgt ccctgtgggg      660

ctttgtaaag ggtctttgac acgtactcat tgggagaaat tcgtaagcgt aacatgcgat      720

tttttcgaat cacaggcccc cgccacgggg agcgagaaca gcgctgtcaa tcagaaacct      780

acaaatctgc ctaaggttga agagtcccaa caaaaaaaca caccccctac agacagccct      840

agcaaggccg gaccaagggg gtcagtgcag tacttgcctg acttagacga caaaaactca      900

caggagaagg gaccacagga agcctttcct gtgcatttgg atctgacgac caatccccag      960

ggcgaaaccc tggacatcag tttcctgttt ttggagccta tggaagaaaa actggtggtc     1020

ctgccctttc ccaaggaaaa ggcaaggacc gcggaatgtc ccggacccgc tcaaaacgcc     1080

tctcctttag ttctgccccc c                                               1101


<210>  4599
<211>  444
<212>  DNA
<213>  Homo Sapiens

<400>  4599
acaccttccg ccagtagggg gccacgttca tatcctcatc tggagggtga cgtgaggtgg       60

aggagactct tttccagtac acacttcttt ctgcgtgtgg accccggagg cagagtccaa      120

ggcaccaggt ggcgtcatgg gcaggacagc atcctcgaga ttagatccgt ccacgttggg      180

gtggtcgtaa ttaaagcggt ctccagtggc ttttacgtgg caatgaacag aagaggaaga      240

ctctatggaa gcagactcta tacagttgac tgtaggttta gagaacgtat cgaggaaaat      300

ggtcataata catacgcatc tcagagatgg cgacgtcggg gccagccaat gtttctggcc      360

ctcgacagac gcggcggccc ccgacctggg ggccgtacac gtcgatatca cctgtctgct      420

cacttcctgc ctgtccttgt ctct                                             444


<210>  4600
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  4600
gcccccaccg cccctaatgg cacactggag gctgaactcg agagacgatg ggagtctctg       60

gtggcattgt ccttggcccg gctccctgtg gccgcccagc ccaaagaggc tgccgtgcag      120

tccggcgcag gcgattacct tcttggcatt aagcgactga gaaggctgta ttgcaatgtt      180

ggaatcggtt tccatctgca ggccctgccc gatgggagga tcggaggcgc ccacgccgat      240

accagagatt ctcttctgga gctgtcaccc gtggagcgcg gtgtagtaag catttttggc      300

gttgcctcac gattctttgt ggccatgagc agcaaaggga aactgtacgg atctcctttc      360

ttcactgacg aatgtacgtt caaagagatt cttctcccca ataactacaa tgcctatgag      420

agctataaat atcctggcat gtttatcgcg ttgagtaaga acggcaagac aaagaagggt      480

aatcgcgtgt ctccaaccat gaaagtgacc cacttcctgc cacgtctg                   528


<210>  4601
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  4601
caggaaggac cagggcgcgg gcccgccctg gggagggaac tggcatcctt gtttagagcg       60

gggcgggagc cccagggagt gagccagcag catgtccgtg aacagtccct ggtcactgat      120

caactgtcca gacgtctgat tcgcacttac cagctgtact cacggacttc cgggaaacat      180

gtccaggttt tggccaacaa aaggataaac gccatggccg aagacggcga cccctttgcc      240

aagctgattg tggagaccga tactttcggc tctcgcgtac gagtgcgggg cgccgagacg      300

ggtctctata tatgtatgaa caagaaaggc aagctgattg ccaagtcaaa cggaaagggt      360

aaagattgtg tcttcaccga gatcgtgctc gaaaacaact acactgccct tcagaacgct      420

aagtacgagg gctggtatat ggcttttaca aggaagggcc gtcctcggaa ggggtccaag      480

acccgtcagc atcaaaggga ggtgcacttt atgaagcggc tgcctcgtgg gcaccacaca      540

acggagcaga gtctgagatt cgaatttctc aactatcctc cctttaccag aagtctgaga      600

gggtcacagc ggacctgggc cccagagccc cgc                                   633


<210>  4602
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  4602
cggagagtag ctgtcaccgc ccgacacctc agcagactcg tggttggcgc tgctgtatgg       60

cgcggcgcag gccgcgcatt ccttctcatc gaggacctga ccgggagttg ttttgagccc      120

ttgccacagg gtcttctgct tcatgagctg cctgacaggc ggtcatgtct ggccgctgga      180

catcagtggc gcggatatac agtttcctcc cacaca                                216


<210>  4603
<211>  1239
<212>  DNA
<213>  Homo Sapiens

<400>  4603
ctttggggcg gtctgctgcc accaaggacc gaactgcccg cttctcgacc tcctgaggat       60

cgtctgccac ggaggcccgc ccgtagcggc ggtccagctc ccgctccccg cttcccactg      120

cctcctcccc tggcatggga tgccaggggt ggcagcctca agactttccg cgcactgctt      180

acccttgccg cgggcgcgga tggccctcct aggcagagcc gaagcgaacc acggtggcat      240

gtgagcgccc ggcagccccg accggaggaa agcgccgctg tccacggtgg cgtgttttgg      300

agccgcgggc tggaagagca ggtgcccccg gggttttctg aagcacaagc cgctgcctgg      360

ctggaggcag ctcgaggagc caggatggtg gccctggagc gggggggttg cggtagaagc      420

agtaaccgtc tggcaagatt tgccgatggc acccgcgctt gtgttaggta tggcattaac      480

cctgaacaga tccagggtga ggcactgagc tactacctcg cgcgcttatt gggcctgcag      540

agacacgtcc cacccttggc gctcgcacgt gttgaagcac gcggagcgca gtgggctcaa      600

gtgcaggagg agctgagagc cgcgcactgg actgaaggaa gcgtggtcag tctcacacgg      660

tggctgccaa atctcacaga cgtggtggta cccgcgcctt ggaggtcaga ggatgggcgc      720

cttagacccc tgcgggacgc cggaggcgag ttggcaaact tgtcccaggc agaacttgta      780

gacttggtgc agtggacgga tttgatcctg tttgactacc tgaccgccaa cttcgacagg      840

cttgtttcca acctgttcag tctgcaatgg gatcctcgag tgatgcagcg ggcaacaagc      900

aacctgcacc ggggtccagg cggtgcgctg gtgtttctcg acaacgaagc cggtctggtg      960

cacggctata gagtggccgg aatgtgggat aagtacaatg agccgcttct gcaatctgtg     1020

tgcgtcttca gggagagaac cgccagacgt gtgttggagc tgcaccgcgg tcaggacgcg     1080

gctgcaaggt tactgcggct gtatcgaaga cacgagccac gtttccccga acttgcggct     1140

ttagcggacc cccacgccca gttactccaa cgtcggctgg acttcctcgc aaagcacatc     1200

ttgcactgca aggccaaata cgggcgtcgt tctggtacc                            1239


<210>  4604
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  4604
ttgcctgatc ccggaaattc aacatggcca cccggcgctc aagcgggact ccccgccgca       60

ctggccctcc ccctgcctcg cctgccaagg atcctgtttc ctatggccgg acggccagca      120

cggcctagct ccgattttgt gggctgtgcg cagggcatgt gctgtcatgg gcgacagggg      180

accgttcata tacatacatc ctccgtttca tgctggacgc cctgcccagt gaccggaaca      240

ggtgggactg ccgtgtcacg aaaggatcga gtgctcccac atcggaggca ggtctctttg      300

gcttgtgtgt gcgctgtcgg cgaacgcgca ggccagctgt ggtctcagaa gccggtgcag      360

atggcccgcc cctctgcaag gcatctcctg ccacggggct ctagtcctaa ttcccaagcg      420

gtattgctgc cttctgtttg cccagtgcct tggcctccgg tcggaccttc tccaggtcag      480

ggtgagggac tgtccccggc gttccccggt gttggaacag accgcggtga cagttgggcc      540

ttggtactgc aggtt                                                       555


<210>  4605
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  4605
atgggtagtg gtaatcctgc ccccggcggg gtgtgttggc ttcagcaggg gcaggaagca       60

acatgctcac tcgtcctcca gacagacgtg actcgggcag aatgctgcgc gagcggcaac      120

atcgatacgg cttggtccaa tctgacccac cccgggaaca aaattaatct gctgggtttc      180

ctcggtttag tgcactgcct tccatgcaaa gatagctgtg acggcgttga gtgcggtcca      240

gggaaagcct gccgtatgct gggcggcagg cctagatgtg aatgcgcccc ggattgcagt      300

ggtctgcctg cacgcctgca ggtgtgcgga agcgacggtg ccacgtacag agacgagtgc      360

gagctgcgtg ccgcccggtg ccgtgggcac cccgacctgt ccgtaatgta taggggtagg      420

tgtcgtaagt cttgtgagca cgttgtgtgc ccccgtccgc agtcatgcgt ggtggaccag      480

acggggagtg cccattgtgt cgtatgccgg gctgcccctt gccctgttcc aagctcacca      540

ggacaggaac tgtgtgggaa caataacgtg acatatatat cctcctgtca tatgcgtcag      600

gctacctgct ttctgggccg aagtattgga gtgcgccacg ccggctcctg tgctgggaca      660

cccgaagagc cccctggcgg agagagcgcg gaggaagagg agaacttcgt g               711


<210>  4606
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  4606
cagtttcacg gagagaaagg gatcagtatt cccgatcacg gattctgtca gcccattagt       60

atccctttgt gtaccgatat cgcgtataac cagacaatta tgccaaacct cttgggccac      120

acaaatcagg aagatgccgg gctggaagta catcagttct atcccctggt taaagtgcag      180

tgttctccag agttgcgatt ctttctttgt tctatgtacg cccctgtatg cacagtcctg      240

gagcaggcaa tacccccctg tagatcaatc tgcgagcggg caaggcaggg gtgtgaggct      300

ctgatgaata agttcggatt ccagtggcca gagcgcctgc gctgcgagca ttttccccga      360

cacggagccg agcaaatctg cgtgggacag aaccattccg aggacggagc accggcactt      420

ctgactaccg ctccgccccc aggcctgcag ccaggcgctg gtgggacccc aggcggccct      480

ggaggcggag gcgccccgcc tcgctatgcc accctggagc acccctttca ctgcccccgc      540

gttttgaagg tgccttcata cctgagttac aagttcctgg gtgaaagaga ctgtgccgcc      600

ccatgcgaac ctgcgcgccc tgatgggtct atgttttttt cacaggaaga gacccgattc      660

gccagacttt gg                                                          672


<210>  4607
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  4607
cagcctagct tgcaagatga actgaaggat aacactaccg tgttcactag gatcctggac       60

cggctgcttg atggctatga caaccgactg agacccgggc tgggggagcg ggtgactgag      120

gtgaagacag atatcttcgt cacaagtttc ggaccagtgt ctgaccacga catggagtac      180

accatagacg tgttctttcg acagagctgg aaggacgagc ggcttaaatt caagggccca      240

atgaccgtgt tgagactgaa caacttaatg gcaagcaaaa tttggacacc cgacaccttc      300

tttcacaacg gaaagaagag tgtggcccat aacatgacaa tgcccaataa gctgctgaga      360

attacagaag atggcacact cctgtatacc atgaggctta cggttagggc cgaatgccca      420

atgcaccttg aagacttccc aatggatgcg cacgcatgcc ctctcaagtt cggcagttac      480

gcatacacta gagccgaggt cgtgtatgaa tggacaagag agcccgctag aagcgtggtt      540

gtcgcagaag acgggagtcg gctgaaccaa tatgaccttc tgggccagac cgtagacagc      600

gggattgttc agagctctac cggcgaatac gtggttatga ccacccactt ccatctgaaa      660

agaaaaatcg gc                                                          672


<210>  4608
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  4608
aatatccagg aggatgaagc aaaaaacaat attactatct ttacgaggat tctggaccgc       60

cttctggacg ggtacgataa ccgtctccgt ccggggctgg gcgatagcat cactgaggtt      120

tttacgaata tttatgtcac ttcttttggg cctgtgagcg acacagatat ggaatacaca      180

attgatgtgt tttttagaca gaagtggaaa gatgagagac ttaaatttaa agggccgatg      240

aacattctcc gactgaacaa tctgatggcg agtaagatct ggaccccaga cacgttcttt      300

cacaacggaa aaaaatccgt ggcgcacaac atgaccatgc ctaacaagct gctgaggatc      360

caagacgacg ggacactcct gtacacaatg agactgaccg tgcaagcgga gtgccctatg      420

caccttgagg acttccctat ggacgcgcac tcatgccccc tgaagttcgg tagttatgcc      480

tacaccacct ccgaggttac ttacatatgg acctacaacg ctagtgacag tgtccaggta      540

gcgccagacg gttctagact taatcaatac gatcttctgg gacagagtat cggaaaggaa      600

accattaaat cttcaactgg tgaatatacc gtcatgactg cccacttcca tctcaaacgg      660

aagattggg                                                              669


<210>  4609
<211>  693
<212>  DNA
<213>  Homo Sapiens

<400>  4609
ccccaaacag aaagtaaaaa cgaggcgtca tctcgagatg tcgtgtatgg tccacagccc       60

caacctctgg agaaccaact gttatccgaa gaaactaaga gcaccgaaac agagaccggg      120

tccagagtgg gcaaactgcc agaggctagt agaatcttga acactattct cagcaactac      180

gaccacaagc tccggccagg aatcggagaa aagccaaccg tggtcactgt ggagattagt      240

gttaattccc ttggaccttt atccatcctc gatatggagt ataccataga tataatattt      300

tctcaaactt ggtacgacga gcgactctgt tataatgata catttgagtc cttggttctc      360

aatgggaatg tggtatctca gctttggatc ccggacactt tctttcgcaa ttcaaaaaga      420

acgcatgagc atgaaattac tatgcctaac cagatggtga ggatctacaa ggacgggaag      480

gtactgtata caatccggat gactattgac gctggatgca gcctgcatat gctgagattt      540

cccatggact cccattcatg cccactcagt tttagttcct tttcctatcc agagaacgaa      600

atgatttaca aatgggagaa ctttaaatta gagattaatg aaaagaacag ctggaagctg      660

ttccaatttg actttaccgg cgtgtcaaat aag                                   693


<210>  4610
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  4610
cgctctagga aggtggaaga ggacgaatat gaagactcct caagcaatca gaaatgggtc       60

ctggctccta aatcccagga tacagatgtg accctcattc tgaataagct ccttagagaa      120

tatgataaga agcttcgacc ggacatcggc ataaaaccta ctgtaataga cgtggatata      180

tacgtgaaca gcatcggacc agtgagctct atcaatatgg aataccaaat tgacatcttt      240

tttgcgcaga cctggacgga ctcccggtta cgatttaact ccactatgaa gatcctgacc      300

ttgaactcca acatggtcgg cctgatttgg attccagaca ccatctttag aaactcaaag      360

accgcagagg ctcactggat aacaaccccc aatcagctgc ttcggatctg gaatgacgga      420

aaaattcttt ataccctccg actgacaatt aatgctgaat gccaacttca gctgcacaat      480

tttcccatgg acgagcatag ctgtccctta atttttagct cttatggcta ccccaaagaa      540

gagatgatat accgatggag gaagaatagc gtggaggccg ctgaccaaaa atcctggcga      600

ctgtatcagt tcgatttcat gggtctcagg aacacaacgg aaattgtgac cacgtctgcc      660

ggagactacg tcgtgatgac aatttacttt gagctgagcc gccgcatggg g               711


<210>  4611
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  4611
gccagcaata ttaagatgac tcatcagcgg tgcagctcaa gcatgaaaca aacttgcaaa       60

caggaaactc ggatgaagaa agatgatagc actaaagcac gacctcagaa atatgaacag      120

cttttacaca tcgaggataa cgatttcgcg atgcgtcctg gctttggtgg gtctccagtg      180

cctgtaggaa tcgacgtcca cgtggaaagc attgattcca tatctgaaac caatatggac      240

ttcaccatga cgttttacct gaggcattac tggaaggacg aacgcctgtc atttccatca      300

actgctaata agagcatgac gttcgaccac cgtttgacca gaaaaatttg ggtaccagat      360

atattttttg tccactcaaa acggtccttc atccacgata cgactatgga gaacatcatg      420

ctgagagtgc accctgacgg aaacgtgctg ctctcattgc gaatcaccgt cagtgcaatg      480

tgtttcatgg acttctctcg ctttcccctc gatacacaaa actgctccct cgagttggag      540

tcttatgcat acaatgaaga cgatctgatg ctgtattgga aacacggcaa caaaagcctg      600

aataccgagg agcatatgtc actgagccaa ttcttcatcg aggatttcag cgcgtcttcc      660

ggcctggcat tttacagtag cactggttgg tacaacaggc tctttatcaa tttcgttttg      720

agacgacat                                                              729


<210>  4612
<211>  837
<212>  DNA
<213>  Homo Sapiens

<400>  4612
ctggcccatg ggagaagact gatctgctgg caggcgttgt tacaatgtca aggtgagccg       60

gagtgttctt acgcctacaa tcagtacgcc gaagcctgcg cgcccgtgct ggcccaacat      120

ggcggcggag acgctcctgg cgctgctgcc gctgccttcc ccgcctcagc cgcttcattc      180

tcttctaggt ggagatgtcc tagccactgc atctctgccc tgatacaact caatcacacc      240

cgtcggggac ctgctctcga ggattgcgat tgcgcgcagg acgaaaactg taagagtact      300

aaacgagcta tagaaccgtg cttgcctcgt acatctgggg ggggcgcggg cgggcccggc      360

gccggtggtg tcatgggatg cacagaagct cggcggcgat gtgacaggga ttcccggtgc      420

aatttagctc tgtctagata tttaacgtat tgtggtaagg tgttcaatgg tctgcgatgt      480

accgatgaat gtcggaccgt gatcgaagac atgctcgcaa tgcccaaggc agccttgctg      540

aacgactgtg tttgcgacgg cctcgaacgg cccatctgtg agtctgtgaa ggagaatatg      600

gcccgactgt gcttcggggc tgagctgggc aacgggcctg gcagctccgg gagtgatggc      660

ggtctggacg actattacga cgaggattac gatgacgaac agaggaccgg aggggcaggc      720

ggagagcagc ctctggatga cgatgatggt gttcctcacc ccccgcgccc agggtccggg      780

gcagccgctt ctggaggtcg tggcgacctg ccttacggac ccgggagaag aagctcc         837


<210>  4613
<211>  951
<212>  DNA
<213>  Homo Sapiens

<400>  4613
cgcgatataa cattgagcgg gcacccaagg ctgtcaactc agcacgttgt gctgcttcgc       60

gaggacgagg tcggtgatcc tggtactaag gacctgggac atcctcagca tgggtcacca      120

atccaagaga ctcagagcga ggtggttaca ctcgtgtcac ctcttccagg ctccgacatg      180

gccgcgctgc ccgcctggcg ggctacctca ggcctgacgc tgtggcccca cacagccgag      240

ggccgcgacc tgctgggcgc agaaaaccgg gctctgaccg gcggccagca ggccgaagac      300

cccactctgg ccagcggagc ccaccaatgg ccaggttctg tcgaaaaact gcagggaagc      360

gtatggtgtg atgcggagac actcctctcc tcatcccgca ccgggggcca ggctccgcca      420

tggttaacag atcacgatgt tcagatgctg cgactcctgg cccagggaga ggttgtagat      480

aaagccagag ttccggcgca tgggcaagta ctgcaggtgg ggttctccac tgaagccgcc      540

ctgcaagacc tgagctcccc tcgattgtct cagttgtgtt cacagggttt gtgtgggctc      600

ataaagagac ctggtgatct gcccgaagtg ctgtctttcc acgtcgacag ggtgctcggc      660

ctccggcgtt ccctcccagc tgtcgcgcgt cgatttcatt cccctttact cccttatcgg      720

tatactgacg gaggggcacg gcccgtgatc tggtgggccc ctgatgtaca gcatttgagt      780

gatcccgacg aggaccaaaa ttccctcgcg ttgggctggc tgcagtacca ggcattactc      840

gcccacagtt gcaactggcc tggccaggcg ccttgcccag gaatccacca tacggaatgg      900

gcaagactgg cccttttcga ctttctcttg caggtccatg acaggctcga c               951


<210>  4614
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4614
gatgcagaac cggtgctcgg aggaggccca ggaggagcat gccgcgcccg aagactgtat       60

gtcagttttc gcgaagtggg ctggcacagg tgggtaatcg ccccccgagg attcctggcc      120

aattattgtc aagggcagtg cgccctccca gtcgccctta gcgggagcgg ggggcctccc      180

gctttgaatc acgctgtact ccgggcctta atgcacgccg ccgccccagg cgcagcggac      240

ctcccttgct gcgtccctgc caggttgtcc cctatctcag tgttgttctt cgacaatagt      300

gataatgtgg tgctgcgtca gtacgaagac atggtggtgg acgaatgtgg gtgtcgc         357


<210>  4615
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  4615
acggccctcg caggcactcg gactgcacaa ggatcaggcg gcggagccgg acgcggccat       60

gggaggagag gtaggagccg ctgcagtaga aagccgttac acgtggattt caaggaatta      120

ggatgggacg attggattat cgccccgctt gattatgagg cataccactg tgaaggtctg      180

tgtgatttcc ccttgcgctc ccacctggag ccgaccaatc acgccatcat tcagactctt      240

ctgaactcca tggcacccga tgcagctcct gcgtcctgct gcgtccctgc tagacttagc      300

cccataagta ttctttatat cgatgccgca aacaatgtgg tctataaaca gtatgaggac      360

atggtggtgg aggcttgtgg atgtcga                                          387


<210>  4616
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  4616
cttccattcg tacccataag ggaacaattt ttcgagatcc caatgccctc tattatcctg       60

aagctgaagg agccccatac catgagcagg tctcagaagt tccttatctg gctgagtgac      120

ctcttactga tgcgcaaggc cttgtttgat cacttgactg cacggggaat acaggtgtac      180

atctgggtgc tcaacgagga acaggagtat aaacgggcct ttgacttagg agcgacggga      240

gttatgactg actaccccac caaactccgg gacttcctcc ataacttcag cgct            294


<210>  4617
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  4617
aggaggccac atcttttgca cactcctcga gcccccactt tcaggattag actcggtgcc       60

caccgggggg gcagtgggga gctgttggaa aacacaatgg aagctatgga aaatagcatg      120

gcccagagaa gcgacctcct cgaactcgac tgccagttga cccgggacag agttgtcgtc      180

gttagccacg atgaaaacct gtgccgccag tcaggcttaa atagagatgt gggctcactt      240

gacttcgagg acctgcctct gtacaaggag aagcttgaag tgtatttttc tcccggacac      300

ttcgcccatg gttccgaccg gcgcatggta aggctggagg acctgtttca gcggtttcca      360

cgcaccccca tgtctgtcga aattaagggg aagaacgagg agctcattag agagatcgcc      420

ggtttggtcc gacggtatga ccggaacgaa attaccatat gggccagcga aaaaagctca      480

gtcatgaaga agtgcaaagc ggcaaatccc gaaatgccac ttagc                      525


<210>  4618
<211>  1080
<212>  DNA
<213>  Homo Sapiens

<400>  4618
gagggcttca cagtggaggc cctttggggc aaaaccgagg aggaggcaaa gcagctcgct       60

gaggaaatga acatcgcttt ctacacatcc cggaccgacg acatcctcct gcaccaggat      120

gtagaccttg tgtgtataag tatcccgcca cctctgactc ggcagatttc tgtaaaagcc      180

ctgggaattg gtaagaacgt agtgtgcgag aaggcggcaa caagtgtgga tgccttcagg      240

atggtgacag ccagtaggta ttatccccag ctgatgtcat tagtcgggaa tgtcctgcgg      300

tttctgccag ctttcgtgag aatgaaacag ttgatttctg agcattacgt tggagccgtg      360

atgatctgcg atgccaggat ttatagtggt agtctgctct cacctagcta tggctggatc      420

tgcgatgagt tgatgggggg gggaggactc cacaccatgg gaacttatat cgtagacctg      480

ctcactcacc ttaccgggcg tagggccgaa aaagtccatg ggctcttgaa gaccttcgtg      540

cgtcagaacg ccgctattag gggaattcgt cacgttacta gcgacgattt ctgttttttc      600

cagatgttga tgggcggcgg agtgtgtagc acggtgactc tgaatttcaa catgccagga      660

gcctttgtgc acgaggtcat ggtggtcggg tccgctgggc gtctcgtggc acgcggcgct      720

gacttgtatg ggcaaaaaaa cagtgccaca caagaggagc tcctgctgcg ggactctctt      780

gctgtggggg caggtcttcc agaacagggc ccccaggatg tgcctctgct ctatctcaag      840

gggatggtgt acatggtgca agctttgcgc cagagttttc aaggccaggg cgacaggaga      900

acgtgggaca ggacaccagt cagtatggct gcctccttcg aggatggcct gtacatgcaa      960

tctgtagtgg acgcaataaa gaggtcctcc cgttcaggtg aatgggaggc ggtggaagtg     1020

ctcactgaag aacctgatac gaatcaaaat ctctgtgagg ccctccaacg gaacaatctg     1080


<210>  4619
<211>  999
<212>  DNA
<213>  Homo Sapiens

<400>  4619
tctcagacaa acaactgcac ctaccttagg gaacagtgct tgcgcgatgc caacgggtgc       60

aagcatgcct ggagagttat ggaggatgcc tgtaatgaca gcgatccagg tgatccttgt      120

aagatgagaa actcctccta ctgcaattta tctattcaat atttggtgga atctaacttc      180

cagttcaaag agtgcctttg tactgacgac ttttactgta ccgtcaataa gctgctgggg      240

aagaaatgca tcaacaagtc cgacaatgta aaggaagaca agttcaaatg gaaccttacg      300

actcgctctc accatggttt caagggtatg tggagctgcc tggaggtagc cgaggcatgc      360

gtgggagacg tagtgtgtaa tgctcagtta gccagttatt tgaaggcatg ctctgccaat      420

gggaatccat gcgacttgaa acaatgtcag gctgccatca ggttctttta tcagaatata      480

ccttttaaca ttgcccagat gctcgccttt tgcgactgtg cacaaagtga catcccctgt      540

caacagtcca aagaagcctt gcattcaaaa acctgcgccg tcaacatggt ccctcccccc      600

acatgcctct ctgtgattcg atcatgtcag aatgatgaac tgtgtcgcag gcattatcgc      660

acctttcaat ctaaatgttg gcagcgcgtg acaagaaagt gtcacgaaga cgaaaactgt      720

ataagtacac ttagtaaaca agacctgacc tgctcaggaa gcgatgactg taaagccgct      780

tatatcgaca ttcttggcac tgtgttgcag gtgcaatgca catgtaggac tatcacgcag      840

agtgaggagt cattatgcaa aattttccag cacatgctgc accggaaatc ttgcttcaat      900

taccccacct tgtcaaacgt gaagggaatg gccctctata ccaggaagca tgcgaacaaa      960

attacactga cagggtttca ctctcccttt aacggagaa                             999


<210>  4620
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  4620
ccgagcgcat ctaaggagcc agataatcac gtttacacta gagccgccgt cgctgcagac       60

gcaaaacagt gtcttgagat tggccgggat acccttcgcg atggcggcag tgcagtggac      120

gctgctatcg ccgcccttct gtgcgtcggc ctcatgaacg cccactcaat gggcatcggc      180

gtgggcctgt ttttgacaat atacaactcc actacccgga aggccgaagt tataaatgcc      240

agggaggtgg ctccaagatt ggcatttgcc tctatgttca acagttctga acagagtcag      300

aagggcggcc tgagcgtggc agtgcccggc gagattagag ggtacgagtt agctcaccag      360

cgccacgggc ggttgccatg ggcaagattg ttccaaccga gcatccagtt ggccaggcag      420

ggctttccgg ttggtaaggg ccttgcagcc gtcttagaga ataaacggac tgtgatcgag      480

cagcagcctg tgttgtgcga agtgttttgt cgtgatcgga aggtgctgag agagggagag      540

cggttaaccc ttcctcgcct cgcagacaca tacgagatgc tggctattga aggggcccaa      600

gcattctata atggatctct gatggcacag attgttaaag atatccaggc tgctggcggc      660

atagtcactg ccgaagatct gaacaattat tgcgctgagc tcatagagca ccctctcaac      720

atcagcctgg gagacgcggt cctgtatatg cccagcgccc gcttatctgg acccgtactg      780

gcattaatcc tgaacatcct taaggggtac aacttctccc gcgagagcgt cgaaaccccc      840

gaacaaaagg ggttgaccta ccaccggatc gtagaagcgt ttaggttcgc atacgcgaaa      900

cgaacactgc tgggtgatcc caagtttgtc gacgtgaccg aggtagtacg gaacatgact      960

tccgagtttt ttgctgcaca gttgcgttcc caaatcagcg accataccac ccacccaatt     1020

agttattaca agcccgaatt ctatactcca gacgacggag gcacagcgca tctctccgtg     1080

gtagccgagg atggctcagc agtgagcgct acttccacaa tcaatctcta ctttggtagc     1140

aaggtgtgct ctcctgtctc tggaatttta tttaataaca tggacgactt tagttccccc     1200

tcaattacta acgaattcgg agccccaccc tcacccgcca actttatcca gcccggtaag     1260

cagcctctgc ttagcatgtg tccaactatt atggtcggcc aggatggcca agtcaggatg     1320

gtcgtcggag ctgccggcgg aacccaaatc accactgata cagccctggc aatcatatac     1380

aatttatggt ttgggtacga tgtgaaaagg gcagtagagg aacccagact gcataacaaa     1440

ctgctgccaa acgtgaccac cgtggaaagg aacatcgacc aggctgtaac agccgctctg     1500

gagacgcgcc accatcatac gcaaatcgcc tcaacgttca ttgctgtggt tcaggcaata     1560

gtaaggaccg ccggtggatg ggcagccgcc agcgactccc ggaaaggagg cgaacctgcc     1620

gggtac                                                                1626


<210>  4621
<211>  1539
<212>  DNA
<213>  Homo Sapiens

<400>  4621
ctgctcagac agcagcgatc ccaagacgca aggctctcct ggcttgccgg cctgcagcac       60

agagttgctt ggggcgccct cgtttgggct gctacctggc agagaagacg ccttgagcag      120

tcaacattgc atgtccacca gagccaacag caagctctga ggtggtgcct gcagggagca      180

caaagaccac actgttcact gcgacgtagt accgacatca gcacgttccg gaatcatctg      240

cctttaacca aggcaagcca aacacagcag gaagacagcg gcgagcagcc acttccacct      300

acttctaacc aggatttagg ggaggcttcc ctgcaggcca cacttctggg gttagccgcg      360

ttgaataagg cctaccccga ggtgctggct caggggcgga ctgcgcgggt gacacttaca      420

agtccttggc ctcgaccgct gccctggcca ggaaacacct taggacaagt gggcactccg      480

ggcaccaagg atcctcgggc cctgctcctc gacgcactca ggtccccagg actgcgggcg      540

ctggaagctg gcactgccgt cgagctgctc gacgtattcc tgggacttga gactgacggg      600

gaggaattgg ccggagctat cgcggcaggg aatcccggcg ccccgctcag agagagagcc      660

gccgagctcc gcgaagcttt agaacaggga ccaaggggac tggcactcag gctttggccg      720

aagctgcagg tggtggtaac actggacgca ggcggccagg ccgaagcagt ggctgccctg      780

ggggccctgt ggtgtcaggg cctggccttc ttctcccccg cctatgcagc ctccggcggc      840

gtgctcgggc tcaacctgca acctgagcag ccacacggcc tgtatctttt acccccgggg      900

gcaccgttta ttgaactgct cccggtcaag gagggtaccc aggaggaggc cgcttctact      960

cttctgctgg ccgaggctca gcaaggaaaa gagtacgaac ttgtattaac cgacagagcg     1020

agcctgacaa gatgtaggtt aggagacgtg gtgagggtag ttggtgcgta caatcagtgt     1080

ccggtcgtac ggtttatttg ccgtttggac cagaccttgt cagtgagagg cgaggacatc     1140

ggggaggacc tcttcagcga ggccttaggt agagccgtcg gacagtgggc cggggccaag     1200

ctgctcgacc acggctgcgt agaatcctca atattggact cctcagcggg cagtgccccc     1260

cactacgagg tatttgtggc cctccggggg ctgaggaacc tgagtgagga gaacagggac     1320

aagctggacc attgtttaca ggaggcctca ccccgctaca agtccctgcg tttttgggga     1380

tccgtgggtc cagcaagagt gcacctcgtg ggacaaggag cgttcagggc tcttagggcc     1440

gcgctcgcgg cttgccccag tagtccgttc ccgccggcta tgcctcgggt cttgcgtcac     1500

cggcacctcg cccagtgcct gcaggaaaga gtggtttcc                            1539


<210>  4622
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  4622
atgatgaaca ttcgcttcaa tcacccgctg tacggtagct tcgggaccca gattatacac       60

atcggcgcct ttcagggaat ggtatctatc agggacaaca acattttctc agaatgggat      120

ggtattttgg actataagaa tgcactgctc gttgcaaaag tttttaacaa gatggcttgc      180

gtcctggcga gaatggataa ggccgtgttt ccgtctttag acgacatatc taaggccctc      240

gataagcagg ccttcaaata ctacccctct actcggggct tgacgtatac agtcctgccc      300

tcctgggtga aaaacctggc acagtacgga aagccaatca aaaatatgtg ccgggacgac      360

cctacatatt tcgcgcagca acagaaggag ggaacagcac tcgcaattga ttccaacagc      420

tgctttgaaa ttcagctcct gtcttttatg ggcttattta tttgcggaga aactccgggg      480

ctg                                                                    483


<210>  4623
<211>  1536
<212>  DNA
<213>  Homo Sapiens

<400>  4623
cagtggcgag gactcagctc cgcgcttagg gccctggaag cacagcgagg tagagaacag       60

cgggaagatt cagctctgcg ctccttcctg gccgagttgt ctagagcccc acggggggct      120

agtgctcccc cccaggatcc cgcctcaagt gcccggaata agcgcagcca ttccggcgaa      180

cctgctcctc acattcgggc cgaaagccac gacatgctga tgatgatgac atactccatg      240

gtccccataa gggtgatggt ggatctttgc aatagcacaa aagggatctg tctgaccgga      300

ccttccggac ctcccggacc tccaggcgcc ggagggctcc caggtcacaa cggcctcgac      360

ggacagccgg ggcctcaagg acctaagggg gaaaagggag cgaacggaaa aaggggcaaa      420

atgggcatcc ctggcgccgc cggaaacccc ggcgaaagag gcgaaaaggg agaccacggt      480

gaactgggcc tgcaagggaa tgagggcccc ccaggccaga aaggggaaaa aggcgataag      540

ggagacgtgt ctaatgatgt actgctggca ggagcaaagg gagaccaggg acctccaggg      600

cctcccgggc cacccggacc cccgggtccc ccaggcccac ccggaagtcg gcgcgcgaaa      660

ggccccaggc aacccagcat gttcaatgga cagtgcccag gagaaacttg cgctatcccc      720

aatgatgaca ccctggtggg caaagcagac gaaaaggcta gtgagcatca cagtccgcag      780

gccgaatcca tgatcacatc tatcggaaac cccgtccagg tgctcaaagt cacagagact      840

ttcggaacct ggatacgcga atcagcaaac aaatccgatg atcggatctg ggtcaccgaa      900

cacttcagcg gcataatggt caaggaattt aaggatcaac cctccctgct caatggaagt      960

tacactttca tacaccttcc ctactacttc cacggttgtg gtcatgtagt gtacaacaac     1020

agtttatact accataaagg cggcagcaat actctggtga gatttgaatt tggccaagaa     1080

acctcccaga cattgaagct ggagaatgcc ctctactttg accgcaagta tcttttcgcg     1140

aatagcaaaa cctatttcaa cttggctgtg gacgaaaagg gtctctggat catttacgcc     1200

agttccgttg atgggtccag catcctggtt gctcagctgg acgagaggac ctttagcgtt     1260

gtgcagcacg ttaatacaac ctaccctaag agcaaagctg gcaatgcctt tatagccagg     1320

ggtattctgt atgtcacaga tactaaggac atgcgtgtca ctttcgcctt cgatttgctt     1380

ggagggaagc agatcaacgc caacttcgac ctgaggacca gccaatccgt gctcgcgatg     1440

ctggcttaca atatgcgtga ccagcatctg tacagctggg aagatggcca ccttatgctg     1500

tatccggtcc agttcttgtc cactacactg aatcag                               1536


<210>  4624
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  4624
aaagaagagg tcaaatcagg aacaaaaggg tcacagccta tgagcccctc cgatttcctc       60

gacaagctca tgggaaggac ctctggatac gatgctcgca taagaccaaa cttcaaaggg      120

cctcctgtta atgtaacctg caatattttc atcaatagtt tcagctctat aacaaagacc      180

accatggatt atagggtgaa cgtcttcctg agacagcagt ggaacgaccc tcgattgagt      240

tacagggaat atcccgatga tagtctggat ctggatccaa gtatgctgga tagcatttgg      300

aaacccgacc tgttctttgc gaacgagaaa ggggctaact tccatgaagt caccaccgac      360

aacaagctgt tgcggatctt taaaaatggg aacgtgctgt acagtattcg gttaacactg      420

atcctgagct gcctgatgga cttaaaaaac ttcccaatgg acattcagac ctgtacaatg      480

caattagagt ctttcggata tacaatgaaa gatctggtgt tcgaatggct ggaggacgct      540

cctgctgtgc aagtcgcaga gggactgacg ctgcctcaat ttatcttacg tgacgagaag      600

gacctggggt gctgtaccaa acattataat actggcaaat tcacgtgcat tgaggtaaag      660

tttcacctgg aaaggcagat gggctat                                          687


<210>  4625
<211>  990
<212>  DNA
<213>  Homo Sapiens

<400>  4625
gtgactgccc agcgcgtgcg ggcacatctc gaggcagccg ggcatgtctg tgttctgaaa       60

gatgctttcg actttgagtc tcggtctgaa atcgcaaact tgatcttggc agagaattgc      120

gaagccgccc tggctctgca tctctacaga ggggggcggc ttctgcaggg gcatcgcatt      180

ccgtttggag tgattttcgg ggggacagac gtgaacgaag atgcgaatca ggctgagaag      240

aataccgtca tggggagagt gctcgaagag gcccgctttg ccgtagcatt caccgagagc      300

atgaaggaga tggctcaggc tcaatggcct cacgctaaag gtaaggttta cgtccaaagt      360

caaggcattg caaccacccc aaacgccgct tttaactgga atacattcct ccagcgaagc      420

gagattaacc agtcagccga taacctgcac atcttccttc tgatatgcgg acttcggcag      480

gtgaaggatc ctttgtatct ggtggatgcc ttctccgcgt ggcaccaaga ggaacctaat      540

gtacaccttg tgattgtagg tccggaggtg gatcccgtgt ttactagaga agtcaaggcc      600

aaagtgaaac gcgccgcagg ggttcgcctc atcggagaga tgccacagga agatctccat      660

gcggtcgtga agaactgctt tgccgtggtc aacagcagcg tctccgaagg catgtctgct      720

gctatactgg aggcaatgga tctcgaggtt ccagtgctgg ctcgcaacat tccaggcaac      780

gcggcggttg tgaagcacga ggtgaccggc ctcttgttca gcaaccccca ggagtttgtg      840

cacctcgcta agcgcctggt atctgatcca gcattagaga aagaaatcgt ggtcaatggc      900

cgggagtacg tgaggatgta tcatagttgg caggtcgagc gcgataccta ccaacagctg      960

atcaggaagc tggaaggatc tactgaggac                                       990


<210>  4626
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  4626
gcttcatctg gcaacttgag gactttcgtg gggtgcgcag tgagagaatt tacttttctc       60

gctaaaaagc ccggatgcag gggtctgcgc atcacaaccg acgcctgctg gggacggtgc      120

gaaacatggg aaaagccgat cttggaacca ccatacattg aggcacacca tcgtgtgtgc      180

acttataacg agacaaaaca agtgacggtc aagctcccga attgcgcacc cggtgtagac      240

ccattttata cgtatcccgt tgcaatacgt tgtgactgcg gtgcctgtag caccgctacc      300

accgaatgcg aaactatc                                                    318


<210>  4627
<211>  690
<212>  DNA
<213>  Homo Sapiens

<400>  4627
cgcatccacc aattagctct gactggggaa aagcgagccg atatccaact gaactccttt       60

gggttttaca cgaatggctc actcgaagta gaactttccg tactccggct ggggctgagg      120

gaagccgagg agaaaagctt gctcgtaggt ttttccctga gcagagtgcg cagcggtcgc      180

gtcaggagct attccactag ggactttcag gattgcccac tgcaaaagaa ttcatcatcc      240

ttcctggtgc tgttcctgat taacacaaag gacctgcaag ttcaagtacg caaatacggc      300

gagcaaaaaa ctctctttat attccccggc ctgctgcccg aagctccttc aaaaccaggg      360

ttaccaaaac ctcaggcaac cgtgccacgc aaagtggacg gaggagggac tagcgccgct      420

agcaagccaa aatccacccc cgcagtcatc caggggcctt ccgggaaaga caaagacctg      480

gtcctggggc tgagtcattt gaacaatagt tacaattttt cattccatgt agtgataggt      540

tctcaggctg aagagggtca atacagctta aactttcaca attgcaacaa cagcgtcccc      600

ggcaaggagc acccctttga cattacagtg atgattagag aaaagaaccc cgacggtttt      660

ctgagtgcgg cggagatgcc actgttcaaa                                       690


<210>  4628
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  4628
actcattggt gccagggtac tcaacgagtg cccaagcccg ggtgcggaca gggcgggagg       60

gctaactgcc cgaatagtgg agccaacgct actgccaacg gcacagctgc ccctgcagcc      120

gcggccgctg ccgccaccgc gagcggcaat ggtccccctg gtggcgcttt atactcatgg      180

gaaaccggcg atgatcggtt tctcttcaga aattttcaca ccggaatctg gtactcttgc      240

gaggaggagc tgtccggcct gggggagaaa tgccgtagtt tcatcgactt agcccctgca      300

tcagagaag                                                              309


<210>  4629
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  4629
cattggtgtg aggggacccg gcgcgtagtc aagcctctct gccaggatca gccagggggc       60

caacactgta tccacttcaa aagggataat tcttccaatg gccgcatgga caacaactcc      120

caggccgtat tatacatctg ggaattgggc gacgacaagt tcatacagcg agggtttcat      180

gtcggtctgt ggcaatcctg tgaggaaagt ctcaacggcg aggatgaaaa gtgccggtcc      240

ttccggtctg tggttccagc cgaggagcag gga                                   273


<210>  4630
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  4630
tccggaccta gaagacagtg gcaccccctt gccagttgca gttcctggtc caggccacag       60

tctcaggggt ctacacccgg tgtgttatgc aaaactggta tgggtcggga acctatcccc      120

gagactcagt gtcacttcgc caatagtatg tgtagcctcc atgtgtccgt tccttacttc      180

ggaaattccc ctaacatcag taactttttt aggtggtccc tggcgttatc accacgacag      240

tggtgcgatc tgggtagctt gcagcctccc agtccaaggt tcaagggctt cagctgcctg      300

tctctgccat cttcatggga ttatcggcgt gctcctagtc cagccaattt ctgtatcctg      360

gtggaaatgg gattccacca cgtgggtcag gctgaccttg aactgcttac gagtgccgat      420

ttgcccacaa gcgcctctca gtccgccggc ataacaggcg tcagtcatca cgcatggccg      480

cagaccttgt cccttctgct gtac                                             504


<210>  4631
<211>  1200
<212>  DNA
<213>  Homo Sapiens

<400>  4631
gcagctggct tgcagggcag gccagcccgg cgatgctatg ctgtcggccc agctcaatcc       60

ccccctacct tcggctttct tcttgacatt gatggcgtgc tcgtgagggg gcatcgcgtc      120

atccccgccg ctttgaaggc cttccgccgc ttagtaaaca gccaggggca gctccgggtc      180

cccgtagtgt tcgtcaccaa tgccggaaat attctccagc acagcaaggc gcaggaatta      240

tccgctcttc tcggctgcga ggtcgacgca gaccaggtga tcttgagcca ctcacctatg      300

aagctcttca gcgagtatca cgagaagaga atgcttgtta gcggacaggg ccccgtcatg      360

gagaatgccc agggtctcgg ctttcgaaac gtggtgacgg tagacgagct gcgaatggcc      420

tttcccctgt tagacatggt ggacttggag aggcgtctta agacgacccc gttgccccga      480

aacgactttc cacggattga aggcgtgctc ctgttaggag agcccgttag gtgggaaact      540

tctttgcagt tgataatgga cgtccttctt tcaaacgggt cccccggcgc tgggctcgcg      600

acaccaccat atccccacct gccagttctg gcgtcaaaca tggacctgct ctggatggcg      660

gaagctaaga tgcctcgctt cggtcatggt acctttctgt tgtgcctcga aacaatatac      720

cagaaggtga ctggcaagga gttacgatat gagggactga tggggaaacc atcaatttta      780

acctaccagt atgctgagga tcttatccga aggcaggcag agagacgtgg atgggccgcc      840

ccgatccgca agctgtacgc agtgggtgat aaccctatga gcgatgtgta cggcgccaat      900

ctctttcatc agtatctgca gaaggcgacc cacgatgggg ctcctgagct gggggccgga      960

ggcacaagac agcagcagcc cagtgcaagc caatcctgta tcagtatact cgtttgtaca     1020

ggggtgtata atccgcgaaa tccccagtca acggagccag tgttaggcgg tggggaaccc     1080

ccatttcatg gacacagaga cctgtgcttt tcccctggcc ttatggaggc ctctcacgtg     1140

gtaaatgacg tcaacgaggc agtgcagctc gtgtttcgca aggagggctg ggctctcgag     1200


<210>  4632
<211>  1506
<212>  DNA
<213>  Homo Sapiens

<400>  4632
ataaagggcg aggctaagaa agagaaaggc atgacctttc ttcctacgac cgtgtcaggg       60

ctgagggagg aggagcgcaa ggagaagggg gtcgccttcc tggccacaac cgagcttccg      120

gcccgatcta tcgacctctc cgccctcaat ctgacagagc tggttaatgg catgctgtct      180

cgcgcactca aggacagtaa gaagtttttt agcctcctgt ctgtgacctc ctacagctca      240

ttcgcatttc ataaatttag cgttgccgtg tataacatca gtaacttgaa aactgttgac      300

ccagccaagt ttcctacacg gtattgctat tgcttgaaca accggacgaa cgatctgagt      360

gacttcaccg ccctgctggt ggacatcatc gggaatagta cctcttactt gactgagatc      420

tttaagagca ctagcatact gagtgtgaat caatccaacg agagcgattg tatctttatt      480

tgcgtgatga cagggaagtc tggaagaaac ctgtccgact tttgggagat tgaagaaaaa      540

taccctatta tcaattatac tttcactagc ggcctgtcag gagttctcgg cgcagcgaca      600

cgtggtactg cccgaacctc taagccaacc accaaatccc agaagacctt gccttccact      660

agtcccggtc attggacaca gtccacgcca tgggcttccg ccctgcggtc tagcccctgg      720

acagagactg ccgcaccatc cgaaaccgaa gagactctga ataccggacg cccacctgag      780

ctccctgcca gagcaaccgc cacatggttc agtgcctccc acacactccc agctctggct      840

acccgacgag tcgctaggac ccagtggctc acagctgatc gtcagacctg ggcaagtatc      900

tctagtgttc catgggcaca gaccataagc gagaagaagc cgggcggatc cctgtgggag      960

acccggtcta gcccgccgac aacggccggt actgaagagg ctatgaacac aaccagcctt     1020

ttggctcctg ccgccgaaat tatggcaacc ccgggcagtc cgagccaggc atctcccacc     1080

cttggagcct ttacgcacgg cacgcagact ccttccccca caaaagcaac tgccccccgg     1140

tatccccaga caggcgatct ttctgctgaa tggcccttca ccgccggcga ggagccagtg     1200

ttggtgccgc ggcctcatca ggtgtctcgg tgccctcagc cgctctttaa ggtcggggct     1260

atggctgcgg cgcccctcac attggcaatc cagagactga atccatgttt gatggaatta     1320

tgccagtttt tccagcagtg tctgtgcatg tcacagcgga gccccaggac agaagatatg     1380

cgctactgcc tggaatacta cagttggttt cttaagaacg caacctatat atgtcaacga     1440

gttaagcggg tatcacatag tcatacttta aagcagaagt gcctggaaaa catctgtaaa     1500

tctgtc                                                                1506


<210>  4633
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4633
cagatgagtc aggcactttg cttcagtaag ataggtggcg aggacggcga catccacaga       60

ggctttcaat ctttgctggt ggcgattaac cggacggaca ctgagtacgt tctgaggaca      120

gccaacggcc tgttcggtga aaaatcctat gacttcctga cagggtttac tgattcttgc      180

ggcaagtttt accaggccac aattaagcaa ctggacttcg tgaacgacac cgaaaagtca      240

acgaccagag tgaactcttg ggtagctgac aaaactaaag gcgagaatat cttactgttc      300

tacttcgata atattttgaa ctctttcatc gtttcatctt tacagaactg ccagatt         357


<210>  4634
<211>  1059
<212>  DNA
<213>  Homo Sapiens

<400>  4634
atggaaaaaa ctttagagac agttcctctc gagcgaaaaa aacgagagaa ggagcagttc       60

cgcaagctgt ttattggggg actttctttt gaaacaaccg aggagagcct gagaaactat      120

tacgaacagt ggggtaagct gacagattgc gtggtgatgc gcgaccccgc gtccaaacgc      180

agtcggggct tcggctttgt gaccttttcc tcaatggctg aggtggacgc tgccatggca      240

gcaagacctc attccatcga tggccgtgtc gtcgagccca agcgcgccgt ggcgcgggaa      300

gagagcggta agcctggagc acatgtaacc gtgaaaaaac tgttcgtcgg cggaatcaag      360

gaagacaccg aggagcacca cttaagagac tactttgaag agtatggaaa gatcgatacc      420

atcgagatca ttactgatag gcagagtggc aaaaaacgtg gtttcggttt tgtcactttt      480

gacgaccatg accctgtgga taaaattgta ctgcaaaagt atcataccat taacggccac      540

aacgccgagg tgcggaaagc tttgtctagg caggaaatgc aggaggtgca aagttctaga      600

tctggaagag gcggaaattt cggttttggc gactctagag gtggcggcgg caacttcggc      660

ccaggacctg gaagcaactt cagaggcggt tcagatggat atggcagtgg ccgaggattt      720

ggtgatggtt acaacggata tggcggcggc cccggcggcg ggaacttcgg gggtagcccc      780

gggtatggtg gcggcagggg tgggtacgga ggcgggggac cagggtacgg aaaccagggt      840

ggaggctatg gaggtggata tgacaactat ggaggaggga attatggctc aggtaactat      900

aacgattttg gcaattacaa ccaacaacca tccaactacg gcccaatgaa gagcggcaat      960

tttgggggaa gcagaaacat gggaggcccg tacggaggcg ggaactatgg cccaggtgga     1020

agcggcggct ccggtggcta cggcggtaga agtcggtac                            1059


<210>  4635
<211>  1164
<212>  DNA
<213>  Homo Sapiens

<400>  4635
gtcgattctg gcaacgatgt cacagatatc gcagacgacg gctgtccaaa gcctccagaa       60

attgcccacg gttacgtgga gcattctgtg cggtaccagt gtaagaatta ttacaagctc      120

cgcaccgaag gtgatggcgt ttacacactg aatgataaaa agcagtggat taacaaggcg      180

gtgggagata agctgcctga gtgcgaggcc gacgacggat gtcccaagcc tccggagatc      240

gcacatgggt atgtggagca ctctgttcgg taccagtgta agaactatta taagcttagg      300

acagaaggag acggtgtcta taccctcaat aacgagaaac agtggatcaa caaggcggta      360

ggtgataaat tgccggagtg tgaggcggtg tgcggtaaac cgaaaaatcc cgcgaaccct      420

gttcagcgaa tcttaggggg acacttagac gccaagggct catttccgtg gcaggctaag      480

atggtgtcac atcataacct gaccaccgga gctaccctca taaatgaaca gtggctgctc      540

accactgcta agaacctgtt tctgaaccat agcgagaacg caacagcaaa ggatattgcg      600

cccactctca ccctgtacgt ggggaaaaag caactcgtag agattgagaa agtcgttctc      660

caccccaact atagccaggt ggatatcggc ctcattaaac ttaagcagaa ggtgtccgtg      720

aatgagcggg tcatgcctat atgtttgcca agtaaggatt atgccgaagt cggtagagtt      780

ggctatgtga gtggatgggg tcgcaacgca aatttcaaat tcacagatca cctcaaatac      840

gtgatgcttc ctgtggctga ccaggaccag tgtattcgtc attatgaggg tagtactgtt      900

ccagagaaga aaacacctaa gtctcccgtc ggggtccaac cgatcctcaa cgaacacaca      960

ttctgtgccg gcatgagcaa gtaccaagaa gacacttgtt acggcgacgc tgggagtgcc     1020

tttgccgttc acgatctgga agaggatact tggtatgcta caggcatcct gagttttgac     1080

aagtcatgtg ccgtggccga atatggggtg tatgtgaagg taacgtctat ccaggattgg     1140

gtgcagaaga ctatcgctga gaat                                            1164


<210>  4636
<211>  1044
<212>  DNA
<213>  Homo Sapiens

<400>  4636
atgagcgacc tgggggctgt aatcagtctg ctgctgtggg gacgccaact gttcgccctg       60

tactcaggca acgatgttac cgacatctca gacgaccgct tcccaaagcc tcctgaaatc      120

gctaacggct acgtggagca tcttttccgt tatcagtgca agaattatta ccgccttcgg      180

acagagggcg acggtgtcta taccctgaac gacaagaagc aatggataaa caaggccgtg      240

ggcgataagc tgccagaatg tgaagcagtg tgcgggaaac ctaagaaccc cgcgaatcct      300

gtccagcgga tcctgggtgg acacctggat gccaagggct ccttcccttg gcaggccaag      360

atggtgtccc accacaactt gacgaccggc gcgacactga tcaacgagca atggttgctc      420

actaccgcaa agaacctgtt ccttaaccac agcgaaaacg cgaccgcaaa ggatatcgcc      480

cccactctga ccctgtacgt gggcaagaaa caactcgtgg aaattgaaaa ggtcgtttta      540

catcccaatt atcaccaggt ggatatcggg ctgatcaaac tcaaacagaa ggtacttgtg      600

aacgagagag taatgcccat ttgtctgccc agcaagaatt atgctgaggt ggggagagtg      660

ggatacgtgt ccggctgggg gcagagcgac aacttcaaac tgacagacca tctcaagtat      720

gttatgctcc ctgtcgcaga tcagtatgac tgtattaccc attacgaggg atcaacatgc      780

cctaagtgga aggctccaaa atcccccgtg ggtgtacagc caatacttaa cgagcacaca      840

ttttgtgtgg gaatgagcaa gtaccaggag gacacttgtt acggagatgc aggttccgct      900

ttcgctgttc atgaccttga ggaagacacc tggtacgccg ccgggatcct gagttttgat      960

aagagttgtg ctgtggccga atacggggtg tatgtgaaag tgactagcat acaacattgg     1020

gtccagaaga ccatagcaga aaat                                            1044


<210>  4637
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  4637
actccactgc ctccgacaag cgcccatggt aacgtcgcag agggggaaac aaaaccagat       60

ccagatgtca ccgaacggtg cagcgacgga tggtctttcg atgctacaac tctggatgat      120

aatggtacga tgcttttttt taaaggggaa ttcgtgtgga agagccacaa gtgggataga      180

gaacttatca gtgaacgctg gaaaaatttc ccctcacccg ttgatgccgc attccggcag      240

ggacataact ccgtatttct gatcaaaggc gataaagtgt gggtctatcc tcctgaaaag      300

aaggagaagg gctaccctaa attattgcaa gatgagtttc caggaattcc gagtcctttg      360

gatgccgccg tcgaatgtca taggggagag tgtcaggcag agggcgtatt gttctttcag      420

ggtgacagag agtggttctg ggatctggca actggtacca tgaaagagcg gagctggccc      480

gccgtaggaa actgttcttc tgcactcagg tggctggggc gttattattg ttttcaggga      540

aatcagtttc tgcgatttga ccccgttcgg ggggaggtcc caccacgcta tccacgggat      600

gttcgcgatt actttatgcc ttgtcctggc cgcggtcatg gtcataggaa tggtacaggc      660

cacggcaatt ccacccatca cggccctgag tacatgcggt gctctcctca cctggttctc      720

tccgccctta cttccgacaa ccacggagct acttacgctt tctccggcac acattattgg      780

cgcttggata ccagcagaga cgggtggcat tcatggccaa tcgctcatca atggcctcaa      840

ggtcctagcg ccgtggatgc tgcattctct tgggaggaga aactctacct cgtacaaggg      900

actcaggttt atgtgttcct caccaagggg gggtacacct tggtttctgg atatccaaag      960

cggctggaaa aagaagtggg caccccccac ggtattatac tcgattccgt cgacgcggca     1020

ttcatatgcc ccggcagtag caggcttcac atcatggccg gcaggcgcct gtggtggttg     1080

gacttaaagt caggggctca ggccacctgg accgagttgc cttggccaca cgagaaggtt     1140

gatggcgcgc tgtgcatgga gaaaagctta ggccctaaca gctgctcagc taatgggcct     1200

ggcctgtacc tcatccacgg gcccaacctg tattgctaca gtgatgtgga aaaactgaac     1260

gccgctaagg cattgcccca gccgcaaaac gtgacctccc tgcttggatg cactcat        1317


<210>  4638
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  4638
tattattggg acgacaactt cgaccctgct agcctccagg gagcgcgcgt gttgctgact       60

ggtgcgaatg ctggcgttgg ggaggaattg gcttaccact acgctaggct gggatctcac      120

ctggtcttga ccgcccacac tgaggctctg ctgcagaaag ttgtgggaaa ctgtcgaaaa      180

ctgggagccc caaaggtgtt ctacatcgca gcagatatgg ccagcccaga ggcccccgag      240

tctgtggtgc agtttgcctt agacaaactg ggcgggctgg attacttggt tctcaatcat      300

atcggtggcg ctccagcagg cacccgggcc cgctccccac aggctacgag gtggctgatg      360

caggtgaact tcgtctctta cgtgcaactg acctctcggg cactgcccag cctgacagac      420

tctaaggggt ccctcgtggt tgtgagctcc ctcctgggac gcgtacccac ttcattctct      480

accccatata gcgcagccaa atttgctctg gacgggttct ttggtagtct ccgccgagag      540

ctcgacgtac aggatgtaaa tgtggcaata actatgtgtg tgttaggcct gagggacaga      600

gcctcagctg cagaagctgt aaggtcatca accagtaggc ccagacagcc cgagcaccgt      660

ggagtccccc tgcagtctca gacagccatg tttctgcctc ctactgtacc cggggctcga      720

accctgaccg agactcctct gagaggctgg ccccaaccca agatgaaaag ctctaggcag      780

aaatccaaaa cggagaaaaa tgacggacac cttgagcccg ttaccgcgtg ggaggttcaa      840

gtccctaggg tgaggaggct gtgcagaggc ttggcccgcc cgcacctctt tggtcatgat      900


<210>  4639
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  4639
gacactctga tcatcaattg tccaggcttc ggccaacacc gagtggatcc cgctgcattt       60

caagccgtgt ttgaccgcaa ggcaatcggg cccgtcacga actattctgt ggcgacccat      120

gtcaacatct ctttcacatt atctgctata tggaattgtt acagccgcat tcataccttc      180

aattgtcacc atgcaaggcc gtggcataac cagttcgtcc agtggaatcc tgatgagtgt      240

ggcggaatta aaaaaagtgg catggctaca gagaaccttt ggctcagcga cgtttttatt      300

gaagaaagtg ttgaccaaac acctgccggt ttgatggcgt ctatgtctat cgtgaaagcc      360

acctccaaca cgatctctca gtgtggttgg tcagcttccg ccaactggac tccaagcatt      420

tctccctcta tggacagggc ccgagcttgg cggcgcatgt cacgatcctt tcagatacat      480

catcgtacta gcttcaggac tcgtagggaa tgggtgcttc tgggaatcca gaaaaggact      540

ataaaggtga ccgtcgcgac aaaccaatat gaacaggcta tcttccacgt cgcaatcagg      600

aggcgttgca gacctagccc atac                                             624


<210>  4640
<211>  1374
<212>  DNA
<213>  Homo Sapiens

<400>  4640
cagttgtcaa gagccggccg ttccgccccc ctcgccgccg gctgcccaga ccgttgcgaa       60

ccggcacggt gcccccctca acccgaacat tgtgaaggcg ggcgagctcg cgatgcttgt      120

ggttgctgcg aagtgtgtgg ggctcccgaa ggggcagcat gcgggcttca agaggggcct      180

tgtggcgagg gcttgcaatg tgtcgtgccc tttggggttc cagcctctgc aacagttcgc      240

cgcagagctc aggcaggtct ctgcgtttgc gcaagtagcg agcctgtctg cggtagcgac      300

gcgaatactt atgccaatct gtgccagctt agggcagcgt ctagacggtc agagcgatta      360

cataggcccc ccgtaatcgt gctgcagcgg ggcgcttgtg gccaagggca ggaggaccca      420

aattcactgc gtcataagta caactttatt gcagacgtcg ttgaaaagat cgctcccgca      480

gtggtgcaca tagaattgtt tcgcaagctg cctttttcca aaagggaggt gcctgtcgcc      540

agtggatctg gctttattgt ttccgaggac ggcctgatag tgacgaacgc tcatgttgtc      600

accaacaagc atcgcgtaaa ggtcgagttg aagaatgggg ctacatacga agcaaagatt      660

aaggacgtcg acgagaaggc cgatattgcc ttgatcaaga tcgatcacca agggaagctg      720

cctgtacttc tcctggggcg ctctagcgag ttgaggccgg gagaattcgt ggtggccata      780

ggatctccat tttctttgca gaatacagtc acgacgggga ttgtatcaac cacacaacgc      840

ggaggtaaag aactcggtct gaggaactca gatatggatt acatacaaac tgacgccatc      900

attaattatg ggaactccgg tggtccgtta gtcaacctgg acggggaagt catcggaatt      960

aatacgttaa aggtcacggc cggaatcagt tttgcaatcc cttccgataa gattaaaaag     1020

ttcctgacag agtcacatga taggcaggca aaaggaaagg caatcaccaa aaaaaaatac     1080

atagggatta gaatgatgag tctgacatcc agcaaggcca aagaactgaa ggatagacac     1140

agggattttc ccgacgttat cagcggggcg tatattattg aggtcatccc agacacgccc     1200

gcagaagccg gcggacttaa ggagaacgat gtgatcatat ccattaatgg ccagtccgta     1260

gtgtccgcaa acgacgtgag tgacgtgatt aaacgagaga gcaccctcaa catggttgta     1320

aggagaggaa atgaagatat aatgataact gtcatccccg aagagattga cccc           1374


<210>  4641
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  4641
actgatgcat tgaacgtgct gctcattata gtggatgatc tgaggccaag cctcggatgc       60

tatggcgaca agctggtgag gtccccaaat attgaccagc tggcctcaca ttcattattg      120

tttcagaatg ccttcgctca acaggccgtc tgcgcccctt cccgtgtgag ttttctgacc      180

ggacgccggc cagacaccac tcgtctgtac gactttaatt cttattggag ggttcatgcc      240

ggcaatttct ccactatccc tcagtatttc aaggaaaacg gctatgtcac tatgtctgtc      300

ggcaaagttt ttcatcctgg catatcctct aatcacacag atgattcccc ctatagttgg      360

agtttcccac cttatcaccc ttcttccgaa aagtacgaaa atacgaaaac ttgtagaggt      420

cctgacggag aacttcatgc aaatttactg tgtccggtgg atgtactcga cgtgcccgaa      480

ggcacactgc ctgataagca gagtacagaa caggccatcc agcttttaga aaagatgaaa      540

acttctgcct ccccattctt cctggccgtc ggctaccaca aacctcatat acccttcaga      600

taccctaagg aatttcaaaa gctgtatccc ttagaaaaca ttaccctggc tccagaccct      660

gaagtccctg acggcctgcc cccagttgct tacaacccat ggatggacat caggcagcgg      720

gaggatgtcc aggctctgaa tatatcagtc ccctatggac cgatccctgt ggactttcag      780

cgcaagattc gccagtcata tttcgccagt gtgagctatc tcgacaccca ggtagggcgc      840

ctgctttccg ccttagatga cctgcagctc gccaattcca ctataatagc gtttaccagt      900

gaccatggat gggcgttggg tgagcacggt gaatgggcta aatactccaa tttcgatgtc      960

gccacgcacg tgccattgat attctacgtg cctggtcgaa ctgcgtcact gcccgaggcc     1020

ggagaaaaac tgtttcctta cctggaccca ttcgactcag cttcacaact gatggaaccg     1080

ggaaggcagt ccatggacct cgttgagctg gtaagcctgt ttcccacact ggcaggcctt     1140

gctggcctgc aggtgccacc caggtgcccg gtaccctctt ttcacgtgga gttatgtcgg     1200

gaaggtaaga atctgctgaa gcacttcagg tttagggact tagaggaaga tccgtatctc     1260

ccaggaaatc ctcgggagtt gatcgcctat tcccaatacc cccgaccaag cgacataccg     1320

cagtggaact ctgataaacc aagtctcaag gatataaaga tcatgggcta cagcatcagg     1380

acgatagact atcgttacac agtgtgggtg ggctttaatc cggacgagtt tcttgccaac     1440

ttcagcgaca tccacgcagg agagctgtat ttcgtggatt cagatccatt gcaagatcat     1500

aacatgtaca acgattcaca ggggggagat ctcttccaac tcctgatgcc a              1551


<210>  4642
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  4642
ggaccagaga ctttgtgcgg agccgaatta gtagatgctc tgcagtttgt gtgcggtgat       60

cgcggttttt attttaacaa acctacagga tacggctcaa gctctaggcg ggcgcctcag      120

actggtattg tcgacgaatg ctgcttccga agctgtgact tgcgcaggct cgagatgtac      180

tgcgcacctc tgaagcccgc taaatctgcc                                       210


<210>  4643
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  4643
gagggcgtaa cagatctgcg tctgtggctc tgtcaaccag ccccaagatg cggggagtgg       60

acttacaacc ctctggagca atgctgtgac gatggcgtaa tactcgactt gaaccaaacg      120

aggttatgtg gatcctcttg cactttctgg ccctgttttc agcactgctg tctcgagagt      180

ctcggatcac aaaaccagac agtggtccgt tttaaagtac ccggtatgaa accagattgt      240

aagagcagtc ctatcacacg gatttgtgct caggagtacc atcccaagtc ccccgtatcc      300

cgtagtgacc tcata                                                       315


<210>  4644
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  4644
tgtgggcccg gaagggtcgt tggaagccgc aggcggcctc ccagaaagct ggtgcccctc       60

gcctacaagc agtttagccc taacgtaccc gaaaaaactc tgggcgcgtc cggacggtac      120

gagggtaaga ttgctagatc tagcgagcgg tttaaggagc tcaccccaaa ttacaatcct      180

gatataattt ttaaggacga ggagaacaca ggcgctgacc gcctgatgac tcaaagatgc      240

aaggacagac tcaactcact tgccatatca gttatgaatc agtggccagg ggtgaagttg      300

agagtgacag aaggctggga tgaagacggg caccacagcg aagaaagcct gcattatgaa      360

gggcgggcgg tcgatatcac gacgtctgat agggatcgga ataagtacgg gctgctggcc      420

agactggccg tcgaggccgg cttcgactgg gtttactacg aatccaaggc acacgtccac      480

tgtagcgtaa aaagcgaaca ctctgcagcc gcaaagacag gaggt                      525


<210>  4645
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  4645
ggcctggagt gcgatgggcg gactaacttg tgttgcagac agcaattctt cattgacttt       60

cggcttatcg ggtggaacga ctggatcatt gcacctaccg gctattacgg aaattattgt      120

gaagggtcct gcccggccta cctggcaggt gtgccgggca gcgccagcag cttccacact      180

gcggttgtga accagtatag gatgcgcggg cttaatcccg gaaccgtcaa ttcttgctgc      240

atccctacaa agctgtctac tatgagtatg ctttacttcg acgacgagta caatattgtg      300

aagcgggacg tccctaacat gattgttgaa gagtgtggct gtgct                      345


<210>  4646
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  4646
gctgatggac ctgatgctgc ggcgggaaat gctagtcagg cccaactcca gaataatctg       60

aatgtgggct cagataccac gtctgaaaca tccttctcac tgagcaaaga agcaccaagg      120

gaacacctgg atcatcaggc tgcgcaccag cccttcccca gaccgagatt ccgacaggaa      180

actggacatc cttctttgca gcgggacttt cctcgatcct ttctgcttga tctgccaaat      240

tttcccgacc ttagcaaggc cgacattaac gggcaaaacc ccaatatcca ggtcacaatc      300

gaggtcgtgg acggccccga ttctgaagcc gataaggacc agcatcctga aaataagcca      360

tcctggagtg tgcccagccc tgactggaga gcctggtggc agagatcatt gtctctggct      420

agggccaatt ccggtgatca ggattacaaa tatgattcaa ccagcgacga ttccaacttt      480

ctgaatccac cgcggggatg ggaccatacg gccccagggc ataggacttt cgaaactaaa      540

gaccagcccg agtacgactc aaccgatggg gagggggatt ggtccctgtg gtcagtgtgc      600

tcagtcacct gcggaaatgg caatcaaaaa aggacaagga gctgcggtta tgcctgtacc      660

gctacagaat cacgaacgtg cgaccgcccc aattgtccgg ggatcgagga tacattccgc      720

acagcagcaa ctgaagtttc acttcttgcg gggagcgaag agttcaatgc taccaaactg      780

tttgaggtcg atactgattc atgtgagcgc tggatgtctt gcaagagcga attcctcaag      840

aaatacatgc acaaagtgat gaacgacctc ccgtcatgcc cttgtagtta tcccactgag      900

gtggcctact caactgcgga cattttcgat aggataaaac ggaaggactt tcggtggaag      960

gatgccagcg gcccaaagga gaagttggag atatataaac caaccgctcg ctattgcata     1020

cgctctatgc tcagcttgga atccactaca ctggctgctc agcattgttg ctatggggat     1080

aacatgcaac tgattacaag gggcaaggga gcgggaaccc ccaacctgat ttccaccgag     1140

tttagtgctg aattgcacta taaggtggac gtgctccctt ggatcatctg taaaggggac     1200

tggtcccgtt ataacgaagc caggccccct aataacggac agaaatgcac cgagtctccc     1260

tccgacgagg actacatcaa acagtttcaa gaggcgcgag agtac                     1305


<210>  4647
<211>  1596
<212>  DNA
<213>  Homo Sapiens

<400>  4647
atcataaacc atcctctgct ttttccaaga gaaaatgcca cggtgcctga gaatgaggaa       60

gaaattattc gcaagatgca ggcccaccag gaaaagttac aacttgagca gctgagactc      120

gaggaggagg tagcccgcct ggcagcagaa aaagaggcac tcgagcaggt cgccgaagag      180

gggaggcagc aaaacgaaac ccgagtagcc tgggacctct ggtctacact gtgcatgatc      240

ctgtttttga tgatcgaggt gtggcgccag gatcatcagg aaggtccgtc acctgagtgc      300

ctcggcgggg aagaagatga gctgcctggc ctcggaggag ctcccttgca aggtttaaca      360

ttgcccaata aggccaccct cggacatttc tacgaacgct gcatcagggg agcaactgct      420

gatgcagccc gcacaagaga attcctggag ggcttcgtcg atgacttgct ggaggccctg      480

cggtcactgt gtaatagaga cacggacatg gaggttgagg actttatcgg agtggactct      540

atgtacgaaa attggcaggt ggatcgcccc ctcctctgtc acctttttgt tccctttaca      600

ccaccggaac catatcggtt ccatcctgaa ttatggtgca gcggcaggag tgtccccctg      660

gacaggcagg gttatgggca gattaaggtc gttcgagccg atggggacac cctgagctgc      720

atttgtggca agactaaact cggcgaggat atgttgtgtc tgctccatgg gagaaactct      780

atggcacccc catgcggaga tatggaaaat cttctctgtg ctacagactc actgtacctg      840

gacactatgc aggtgatgaa gtggttccaa actgcgctga ctcgcgcctg gaagggaatc      900

gcgcacaagt acgagtttga tctggccttc gggcagctgg atagcccagg gtccttaaaa      960

atcaaattca gaagtgggaa atttatgccc ttcaatctca tacccgtgat ccaatgcgac     1020

gacagtgatt tatacttcgt gagccacctt ccgcgggagc caagtgaggg aactccggca     1080

tcaagtaccg attggttgct gagctttgcc gtctatgaac ggcacttcct ccggacgact     1140

ctgaaggctc tccctgaggg cgcttgccac ctgtcctgcc tccagattgc ttcattcctc     1200

ctgagtaagc agtctagact gactggccca tccggcctgt cttcatatca cctcaaaact     1260

gccctgcttc acctcctgct tctccgtcag gctgctgact ggaaagctgg tcagctggat     1320

gcccggctgc acgagctgct gtgctttctg gagaaatcac tgcttcaaaa gaaacttcac     1380

cattttttca ttggcaatag aaaagttccc gaagctatgg gcctgcccga agctgtgctg     1440

cgggctgaac cactcaatct gtttagacca tttgtactcc agaggagcct gtatagaaag     1500

acactcgact ctttctacga aatgctgaag aatgctccgg ctctgatcag tgagtattct     1560

ctccatgtgc cttctgacca gccaacccct aaaagt                               1596


<210>  4648
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  4648
cacccattga tggtgagtga cagaatggat ttggacactt tggcccgtag ccgtcaattg       60

gaaaagcgca tgagcgagga aatgcgtctc ttagagatgg aatttgagga acgtaaacgt      120

gccgctgaac agcggcagaa ggcggagaat ttctggactg gcgatacatc ttctgatcaa      180

ctcgtcctgg gcaaaaaaga catggggtgg ccttttcagg ctgacgggca agagggt         237


<210>  4649
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  4649
gaccggtcaa tggagaaaaa aaagggcgaa ccccgcacac gggccgaggc gcggccctgg       60

gtggatgaag acctcaaaga ctctagtgac ttacatcaag ctgaagaaga cgcagatgag      120

tggcaggaaa gcgaggaaaa tgtggagcac atccctttca gccataacca ctatccagag      180

aaagaaatgg tgaagcgcag ccaggagttc tatgagctcc tcaataaacg tcgcagcgtg      240

cgtttcatca gcaacgagca ggtgccaatg gaggtgatag ataacgtgat tagaactgca      300

ggcacagccc caagcggggc gcacactgaa ccctggacct tcgtagtggt taaggaccca      360

gacgtcaaac ataaaatccg caaaattatc gaagaggaag aggagatcaa ctacatgaaa      420

cgtatgggac atcgctgggt gacagacctg aagaagctga ggacgaactg gattaaggag      480

tatctcgaca cagcccctat tcttattctg atctttaaac aggttcatgg gtttgcagcc      540

aatggtaaga aaaaggtgca ttattataat gag                                   573


<210>  4650
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  4650
ggcgatgaac tgctgaacat ctgcatgaac gccaagcacc acaagcgagt acctagcccc       60

gaggacaagc tttatgagga gtgtattccc tggaaggata atgcctgctg cacactgacc      120

acttcctggg aagcacatct ggatgtttct cctttgtaca attttagcct ttttcattgt      180

ggcttgctga tgcccgggtg tcgcaaacac ttcattcaag ccatatgttt ttacgaatgt      240

tcaccaaatc tgggtccctg gattcagccc gtgggcagct tgggctggga ggtggccccc      300

tctggtcaag gcgagagggt tgtcaatgtt cccctgtgcc aggaagattg cgaagagtgg      360

tgggaggatt gccgcatgtc ttacacctgt aaatccaact ggaggggagg atgggactgg      420

tcccaaggaa agaaccgctg tcctaaagga gcacagtgcc tgcccttcag tcactacttt      480

ccgaccccag ccgacctttg cgagaagaca tggagcaact catttaaggc aagccctgag      540

agacgtaatt cagggcgctg tctccagaaa tggtttgagc ccgcccaggg gaaccctaat      600

gtcgcagttg ccaggctgtt cgcctct                                          627


<210>  4651
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  4651
tgtcttcagt gtgacccgct cgttctggaa gccctgggac acctgagatc agcactgatt       60

ccatcacgat tccaactgga gcaactccag gctagagccg gcgcagtgct gatgggaatg      120

gagggaccat tcttcagaga ctatgccctc aacgtttttg ttggtaaggt agaaacaaat      180

cagcttgacc tcgtggcctc ctttgttaag aatcaaaccc agcacctgat ggggaattcc      240

ctgaaggacg agcccctcct tgaggagctc gtgactctga gagccaacgt tatcaaggag      300

tttaagaaag tgctgatttc ctacgagctg aaagcatgta accccaaatt atgtcggctt      360

ctgaaggaag aggtgctgga ttgtctgcat tgtcaacgga tcaccccgaa gtgtatccat      420

aagaagtatt gcttcgtgga ccgacaacct cgcgtggcac tgcagtacca gatggatagc      480

aagtatccga gaaaccag                                                    498


<210>  4652
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  4652
tgcctggaat gcgatccaaa gttcatcgag gatgtcggca gcctgctcgg caatttgatt       60

cctagcgagg tgcccggtcg cacacaatta ttggaaagac aaataaagga aatgatccat      120

ctctcattca aagtgtcaca tagcgacaag cgcctgaggg tcctggcggt gcagcaggtg      180

gttaagctgc gtacgtggct gaagaacgaa ttttataagc tcggtaatga aacttggaaa      240

ggcgttttca tctatcaagg caagttgctc gacgtgtgcc agaatctgga gagtaagttg      300

aaggaattgc tgaagaattt tagtgagata gcttgtagtg aggactgtat tgtggtcgag      360

gggcctattt tggactgctg gacttgtctc aggatgacaa accgatgctt caaaggcgaa      420

tattgtggtg acgaagatcc gcgaaaagca gagaacagag ag                         462


<210>  4653
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  4653
gagacccttc cccagttcag ggtggacggg aggggcggga ataacggtgg ggtttcccgc       60

gtgtcccctg tgtcacgggg ctcccaggag gaagaagagg atgaggatga tagctacacc      120

ttccatcacg gaataacccc cggtgaaatg gggacaggcg gaagctcatc tctttcaaca      180

ttgggtgggt ctttttttac agatcct                                          207


<210>  4654
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  4654
atgcattttc tgactatata cccgaattgc tctagtgggg tagtgcgggc tcaatcccga       60

actgagcaga agaaccctct gggactggat gacttgggca tacaaaacct cggccagacc      120

gtgtctctgg cgcccgcggt ggaggccgcc agcatgctga aaatggaacc ccttaactca      180

actcaccctg gtacggccgc aagctccagc cctttggaaa gccgggccgc cggtggaggc      240

tctggtaatg ggaacgaa                                                    258


<210>  4655
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  4655
ccactctatc agaagagcgt ctggacacag gagtctaagt gtcacctcat tgagacaaac       60

atccgtgatc aggaggagct gaaaggaaaa aaggtgccac agtatccctg tctttgggtg      120

aacgtaagtg ctgccggaag gtgggccgtg ctgtaccata ccgaagatac aagagaccaa      180

aaccaacagt gctcttatat cccaggcagt gtagacaact accagactgc ccgcgccgat      240

gtcgaaaaag ttcgtgctaa gttccaagaa caacaggttt tttactgctt ctcagcccca      300

cgcgggaatg aaacaagtgt gttatttcag cgcctctatg ggccccaagc actt            354


<210>  4656
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  4656
attatcaagg ggtttgagtg taagccccat agtcaacctt ggcaagccgc actgttcgaa       60

aagactcggc tcctgtgtgg agcgactctg atcgcccctc ggtggttact gacggcggca      120

cactgcttga agccgcggta catcgtgcat ctcggacagc acaaccttca gaaggaggag      180

gggtgcgagc agactaggac ggcaaccgaa tcttttccac acccaggctt taacaactct      240

ttgcctaaca aggaccacag aaacgacatc atgcttgtga aaatggcctc cccagtgtca      300

atcacttggg cggtgagacc tctgaccctg agtagcaggt gtgtgactgc cggaacaagc      360

tgtctgatat ctgggtgggg ctctacatca tcccctcaac tgcggctccc tcataccctg      420

cggtgtgcca atatcacgat catcgagcat cagaagtgtg agaatgccta ccctgggaac      480

atcaccgaca ccatggtctg cgcttcagtg caggaagggg gcaaggatag ctgccagggt      540

gatagcggag gacctctcgt gtgcaaccaa agcctgcaag gaataatctc ttggggacag      600

gacccttgcg ctatcacccg caaacctgga gtatatacta aggtatgtaa atacgtggat      660

tggatccaag aaacaatgaa aaataat                                          687


<210>  4657
<211>  693
<212>  DNA
<213>  Homo Sapiens

<400>  4657
gccacaccga agattttcaa tggaactgag tgcggacgga atagtcagcc gtggcaggtg       60

ggtttattcg agggcacctc tctgcgttgc gggggcgtcc tgatagatca tagatgggtg      120

ctcacagcgg ctcattgctc tggatccaga tattgggtcc gattgggcga acactcactt      180

tcacaactgg attggactga gcagattcgc cactccggct tttctgtgac ccaccccggt      240

taccttgggg ccagtacctc ccacgaacac gatctgcgcc tgttgcgcct gcggttgcct      300

gtcagggtga caagctctgt ccaacccctt cccctgccca acgattgcgc aaccgccggt      360

actgagtgtc acgtctctgg ctggggcata acgaatcatc ctcgcaatcc gtttcctgat      420

ctccttcagt gcctgaacct ctcaatcgtg tcccatgcca cttgtcatgg agtttaccct      480

ggccggatta cgtcaaacat ggtttgtgcc ggtggggtgc ccggccaaga tgcttgccag      540

ggggatagcg gaggaccatt ggtttgcggc ggagtgctgc agggattggt gagctgggga      600

tccgttgggc cctgtggtca ggatggcatc cccggagtat acacctatat ttgtaagtat      660

gtcgactgga tccgcatgat catgcgtaac aac                                   693


<210>  4658
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  4658
gtgctcgggg gccatgagtg tcagccccat agccagcctt ggcaggccgc tctcttccaa       60

ggccaacagt tgctctgcgg cggcgtgctg gtgggcggaa attgggtgct gacagcggca      120

cattgcaaga aacctaaata cacagtcagg ctgggcgatc acagcttaca gaataaagac      180

ggtccagagc aagagattcc cgtggtccag tccattcccc atccctgcta taacagttct      240

gatgtggagg accacaatca tgatctgatg ctgctgcagc tccgagacca ggcttcctta      300

gggtcaaaag tcaaacctat ctcactggcc gatcattgca cccagcctgg acaaaaatgc      360

acagtgagcg gctggggtac agtcacaagt cctagggaaa atttccccga tactcttaac      420

tgtgcagagg tcaaaatctt tcctcaaaaa aaatgtgagg acgcataccc tggccagatc      480

actgacggca tggtgtgcgc cggatctagt aagggcgccg acacttgcca gggtgactcc      540

ggtggacctc tcgtttgcga tggcgccctg caaggcataa cttcttgggg ctccgaccca      600

tgcggcagga gtgataagcc cggcgtgtac acaaacatct gtagatacct tgactggatc      660

aagaaaatta tcgggtccaa aggc                                             684


<210>  4659
<211>  1017
<212>  DNA
<213>  Homo Sapiens

<400>  4659
ggcagcctgc actcaccggg cctgtcagag tgctttcaag tgaatggggc ggactaccgc       60

ggtcaccaga atagaactgg acctaggggt gccggccgtc catgtttgtt ttgggaccag      120

acccaacagc attcctatag cagcgcatcc gatcctcatg gccgttgggg tctcggggct      180

cacaatttct gtcggaatcc cgatggagac gttcaaccct ggtgttatgt ggctgaaact      240

gaagagggaa tctactggag gtactgtgat attccctcct gccatatgcc tggttattta      300

ggttgctttg tggattcagg ggctccccca gccctttcag gcccctcagg gacttccacg      360

aagttgactg tgcaggtttg tttacgcttt tgtcgtatga aaggctatca gctggctgga      420

gtcgaggcgg ggtacgcctg tttctgcgga agtgagagcg atttggcaag gggaaggtta      480

gccccagcca cagactgcga tcagatatgc ttcgggcacc cgggccagct ctgtggcggc      540

gacggacgtc tcggagtata tgaggtgtcc gttggatcct gtcagggcaa ttggactgca      600

ccacaggggg tgatctacag cccggatttc cccgacgaat acggacccga tcgtaactgc      660

tcctgggctc tggggcctcc tggtgccgcc ctggaattaa cctttcgcct gtttgagttg      720

gccgatccta gagacagact cgagctcaga gatgccgcct caggatccct tctgcgcgcc      780

tttgacgggg ccagaccgcc accgagcggg ccccttagac tgggtacagc cgcactcctg      840

ttgacctttc gcagtgacgc ccggggacac gctcagggct ttgcattaac atacagaggg      900

ctccaggatg ctgctgagga tcctgaggca cccgaaggat ccgcccagac ccctgccgcc      960

ccacttgatg gggccaacgt cagttgctct cctcgacccg gggccccacc cgcggcc        1017


<210>  4660
<211>  1023
<212>  DNA
<213>  Homo Sapiens

<400>  4660
tccaacagtg atggctcctt tcactacaaa gataagttat acaggagcgc cagtcaggcc       60

ctgcaggcat acatagatga tttcgacttg ggacagattt atcctggcgc ctctacaggg      120

aagattaaca tcgatgagga tttcactaat atgagtcagt tctgcaatta catttacaag      180

cctaacaacg cctttgagaa tctggatcat aaaaagcact caaatttcat tagttgcaga      240

cgacacaccg ttaatgacat cgattctatg tcactgacca ccgatgacct gttgcgtctg      300

cccgctgacg gctccttcag ttacacctac gtcggaccca gtcacagaac ctcaaagaaa      360

aacaagaaat gcagaggccg gttgggcagc ctggacatcg aaaaaaatcc acatttccaa      420

ggtccttaca catcaatggg gaaggataac tttgtgactc ctgtgattcg gtctaacatc      480

aatggaaagc agtgcggcga taaaattgag ctcttaatac tgaaggctaa aaggaatttg      540

gagcagtgca ccgaagagct gcctaagagt atgaaaaagg acgatagccc ttgctccctc      600

gacaagctcg aggctgatag aagttgggag aatattcccg tgacctttaa gagtccggtg      660

cccgttaaca gcgatgactc tccccagcag acttctaggg ccaagtccgc aaagggcgtc      720

ctggaggatt tcctgaacaa tgataatcag tcatgtaccc tcagcggcgg caaacaccat      780

ggaccggtgg aggctctgaa gcaaatgctc ttcaatctgc aggccgtgca ggagcggttt      840

aatcagaata aaaccactga tcctaaagag gaaatcaagc aagtttccga ggatgatttc      900

tccaaactgc agctgaagga aagtatgatc ccgataacca ggtccctgca aaaggccctg      960

catcacctct cacggctgag ggatctcgtg gacgatacca acggggaacg cagtccaaag     1020

atg                                                                   1023


<210>  4661
<211>  1248
<212>  DNA
<213>  Homo Sapiens

<400>  4661
ttctggcttc tcaacgtgct ctttccaccg cataccacac ctaaggctga actgtcaaat       60

cacacgcggc cagtcatttt agtgccaggt tgtctgggga atcagctgga ggctaaactg      120

gacaagccgg acgttgtaaa ttggatgtgt tataggaaga cggaagactt ttttactatc      180

tggttggatc tcaacatgtt cctccctctc ggcgtggact gttggattga caatacccgt      240

gtcgtgtaca accgttcctc tggcctggtt agtaatgcac ctggtgtcca gatccgggtg      300

ccggggttcg ggaagaccta ttccgtcgag tatctggaca gcagcaagct ggccggatac      360

ttgcacactc tcgtccagaa cttggtgaat aacggctatg taagggacga gacagtccgg      420

gccgcacctt atgattggcg cttagagccc ggccaacaag aggaatatta tcggaaactt      480

gcggggctgg tggaggaaat gcacgcagcc tatggcaagc ctgttttcct gatcggccac      540

tccttaggat gcctgcatct gctgtacttc ctgctccggc agcctcaggc atggaaagac      600

cggtttattg acgggtttat cagcctcgga gcgccttggg gagggagcat taaacctatg      660

cttgtgctcg ctagtggcga caatcaaggg attcccatca tgagcagtat taaactgaag      720

gaagagcagc gcatcacaac caccagccct tggatgtttc ccagccggat ggcttggccc      780

gaggatcacg tctttatcag tacaccatcc tttaattaca ccggacggga ctttcagaga      840

ttcttcgcag acctgcactt cgaagaagga tggtatatgt ggctgcagtc aagggacctt      900

ttagccgggt tacctgcccc cggagtcgag gtttattgtc tgtatggagt cggcctccct      960

acaccgcgaa cttacatcta cgaccatggg ttcccataca cagatccggt aggcgtgctt     1020

tacgaagacg gggacgacac ggtagctaca agaagcactg agctgtgcgg cctgtggcag     1080

ggacggcagc cccagcccgt tcacctcctg ccgctccatg gaatccaaca ccttaatatg     1140

gtctttagca atttaaccct cgagcacata aacgctatcc tcctcggagc ctaccgacaa     1200

ggtcctcctg ccagccctac tgcctctcct gagcctcctc cgcccgaa                  1248


<210>  4662
<211>  474
<212>  DNA
<213>  Homo Sapiens

<400>  4662
caccacctgt tagcttccga tgaggagatt caggacgttt ccgggacctg gtatctgaag       60

gccatgactg tggaccgcga attccctgaa atgaatttag aatccgtgac ccctatgaca      120

ctgaccaccc tcgaaggcgg gaacctggag gcaaaagtca ctatgttgat ttcaggccgt      180

tgtcaggaag tgaaagcagt cttagagaaa actgacgaac caggaaagta cactgccgac      240

ggcggcaagc acgtggccta tattatcagg tcccatgtca aagatcacta catcttttac      300

tgtgagggcg aacttcatgg caagccggtt cgcggtgtga agctggttgg ccgggatccc      360

aagaataatc tggaagccct ggaagacttc gaaaaagccg ctggggccag aggcctgagc      420

accgagtcaa tacttattcc caggcaatcc gagacttgtt cccccggcag tgat            474


<210>  4663
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  4663
gcgggctccc aggttcaaga atggtaccct agggaatctc acgcccttaa ttggaataaa       60

ttctcaggat tttggtacat actggcgaca gcaactgacg cccaggggtt tctgcccgct      120

cgcgacaaga ggaaactggg agctagcgtg gtcaaggtta ataaagtagg ccaattgagg      180

gtgctgctgg cattcagacg aggccagggc tgtggccggg ctcagccaag gcatcccgga      240

acttccggcc acctctgggc ttcattgagc gttaagggcg tcaaggcatt ccatgttctg      300

tccactgatt acagttacgg acttgtatat ctgaggctgg gcagagctac ccagaactat      360

aaaaatctcc tcctcttcca cagacagaat gtgtcttcat tccagtctct taaagagttc      420

atggatgcct gcgatattct tggcctgagc aaggctgccg taattcttcc aaaagatgcc      480

tctcgaacac acactatcct gcct                                             504


<210>  4664
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  4664
cagacaccca caccactgcc tcttcctcct cctatgcaaa gctttcaggg gaatcagttt       60

caaggggagt ggtttgtctt agggctcgca gggaattcat tccgcccaga acacagagct      120

cttctcaatg ctttcactgc gacttttgaa ttatctgatg atggccggtt tgaagtgtgg      180

aacgcaatga cccgcggcca gcattgcgat acctggtcct acgtattaat tcccgccgcc      240

cagccaggtc agttcacggt cgaccatgga gtggaacccg gcgccgatcg tgaagaaacc      300

agggtagttg atagcgatta tacgcaattt gctcttatgc tttcaaggag acatacttct      360

cgcctcgccg tgttgaggat cagcttatta ggacgctcat ggttattgcc tccaggcacc      420

ttggaccagt ttatctgcct gggccgtgcc cagggacttt ctgatgacaa cattgtgttc      480

cctgacgtaa caggttggtc cccacaggcc tccgtgtgc                             519


<210>  4665
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  4665
catcacctcc tcgctagtga tgaagagata caagacgtgt cagggacctg gtatctcaag       60

gccatgaccg ttgacagaga attgcctgag atgaacctgg agtctgtaac tcccatgaca      120

ttaaccattt tagaaggagg caatctcgag gcgaaagcaa cgatgctgat tagcggccaa      180

tgtcaggagg ttaaggtgat acttgagaag actgacgagc cgggaaagta tacagccaac      240

cggggcaaac acgtggccta cattattcgg tcccatatga aggaccatta catcttttat      300

tgcgagggcc gcgatccaga aaacaacctc gaggccttag aggacttcga gaaggcggca      360

ggggccagag ggcttagtac cgaatccatt ctgattcctc gccagtctga gacttgctct      420

cccggatccg at                                                          432


<210>  4666
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  4666
ttagagacag ctgatctggc cgagctctgc ggtcagacat ggcaggggga tggtttgctt       60

ttgcgctccc acgcagcctc acgccgattc tacttcgtgg cccccgacac cgattgcgga      120

ctctgggtcc aggccgcagc tccaggagac cggattagat tccagttcag atttttcctg      180

gtctatagtt taacccccgc tcccccagct ttaaacacct cctcccctgc ccccgctgac      240

ccttgtgccc ctggatccta cctccagttc tatgaggggc ccccgggcgc ccccagaccc      300

ctcgggtctc ctctgtgcgg cctcaatatt cccgtcccag tggcatcctc cggcccattc      360

ctggggttac ggttagtgac gcgaggaaga cagcccagag tggactttgt aggcgaagtg      420

acttccttcc ggctgggtcc ctgtggcgct tacttccggt gtcagaacgg gcggtgcatt      480

cctagctcac tcgtttgtga cccatggggt atggataatt gtggcgatgg cagcgaccag      540

ggtagttgga gcccggcaga ctgtcgcggg ccttcacccg tccccagcca gacaggaagc      600

actgatgctc acacaagtcg cagc                                             624


<210>  4667
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  4667
cagctgctgc caggcaataa tttcactaac gaatgtaata ttcccggtaa cttcatgtgc       60

tctaatggac ggtgcattcc tggagcctgg cagtgtgatg gactcccaga ctgcttcgat      120

aaatccgacg aaaaggagtg tcccaaggct aagtccaaat gcgggccgac gttctttcca      180

tgtgcatccg gtatacactg catcatcgga cggtttaggt gtaatgggtt tgaggactgt      240

ccagatggct ccgacgaaga aaattgcacg gctaatccac tcctgtgtag tacagctcgg      300

tatcattgta agaacggcct gtgcattgac aagtctttta tatgcgacgg ccagaacaat      360

tgtcaggata atagtgacga ggaaagctgc gagagcagcc aggaacccgg gagcggacag      420

gtcttcgtca cgagtgagaa tcagttggtg tattatccgt caattaca                   468


<210>  4668
<211>  930
<212>  DNA
<213>  Homo Sapiens

<400>  4668
gggacaagta atttgtcaga gactgaacca ccgctgtgga aggaaagtcc agggcagctc       60

tctgattacc gggtggaaaa tagcatgtac atcatcaacc cgtgggtgta cctggagaga      120

atgggtatgt acaagattat cctgaatcag acggcgaggt actttgccaa gttcgcacct      180

gacaatgaac aaaacatctt atgggggtta cccttgcagt atggatggca gtatagaaca      240

gggcgtctgg ctgaccccac tagaaggaca aattgtggat acgagagtgg ggaccacatg      300

tgtatcagtg tagatagctg gtgggctgac ctgaattact ttcttagcag ccttcccttc      360

cttgccgccg tggactccgg tgtcatgggc atttcctccg accaggtcag attgctccct      420

cctccgaaaa atgagcgtaa gttctgttac gacgtgtcta gctgtagatc ttcctttcct      480

gagacaatga acaagtggaa caccttttat cagtacctgc agagtccttt ctcaaaattt      540

gacgacttac tgaagtatct ctgggccgca catactagca ctctggctga caacatcaag      600

tctttcgaag accgatatga ctactactct aaagctgaag cacactttga acgaagttgg      660

gtgctcgccg tggaccatct cgccgcggta ctgttcccta ccaccctgat ccggagctat      720

aaattccaga agggcatgcc ccctcgcatc ctgctcaaca ctgacgttgc acctttcata      780

agtgatttca ccgccttcca gaacgtggtg ttggtgctgc tcaacatgct cgataatgtg      840

gataagtcaa tcgggtactt gtgcaccgag aaaagtaacg tgtatcggga ccattccgaa      900

agctccagcc ggtcctatgg taataacagc                                       930


<210>  4669
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4669
tcaagagagc ccctccggcc gtggtgtcac ccaatcaacg cgattctggc tgtggagaag       60

gaaggatgcc ccgtgtgcat caccgtaaat actacaatat gtgctggcta ttgtcctaca      120

atgatgagag tgctgcaggc ggtgctgcca ccgctgcccc aagtagtgtg tacttatcgt      180

gacgtgcgct tcgaatccat tcgactgccc ggctgcccaa gaggggtgga tcctgttgta      240

tctttcccag ttgccctcag ttgcagatgc gggccgtgtc ggcgcagtac cagcgactgt      300

ggcggtccca aagatcaccc attaacctgc gatcacccgc agctgagtgg actcctgttc      360

ctc                                                                    363


<210>  4670
<211>  249
<212>  DNA
<213>  Homo Sapiens

<400>  4670
gcgacatgta aggacgagaa gggcaaacag gagatggaga ccggccaaca gccatccgga       60

ctctctgcca cactgacaaa agtcaagtgt gccaaaagac agaagaccgt cgtgcgagtc      120

cgattctaca tgctcagcat gaagaacaag gcctgtagga agaaccttag caaggggtac      180

aatcagcgtc ctgaagggtc caaagaggag agccatatgg tggtaaaaga aaaacgcaaa      240

ggagatcac                                                              249


<210>  4671
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  4671
caacactttt ccgctgccga ttcacccggt accgaattca cacctgcaac aaccacatct       60

cggttgttgc acgtgctgta cgtatgtagt tgttccctcg ttgccgagaa ggacgatttc      120

tcctcacccc atagtcacag tctcctgctg gtgtctctcc cagagcctca ctttgagctg      180

agtgaggggc tccgccttgc cttcaggggc tcacagagct ctgactccat caggtaccgt      240

cggggcggga acgagggagt gaggccttgg cgtgctgggg ccacaggcct gccacccacc      300

ggaaaagaca ttagcgtctc cctggcacat gaactgtact ccctgctcaa gcagctgcaa      360

atgtctatc                                                              369


<210>  4672
<211>  1170
<212>  DNA
<213>  Homo Sapiens

<400>  4672
gtccacatgc ctaccaaggc tgtcgaccct gaagcattta tgaacatctc tgagatcatc       60

cagcaccaag gctacccctg cgaagaatac gaagtagcga ccgaagacgg atatatcctg      120

tccgttaaca gaatcccaag agggctcgtc caaccgaaaa aaacgggctc ccggccagtg      180

gttttgctgc agcatggcct cgtaggcggc gcgtcaaact ggatcagcaa tctgcccaat      240

aattcactgg ggttcattct ggccgacgcc gggtttgacg tgtggatggg taatagtagg      300

ggtaacgcct ggtccagaaa gcacaaaact ctcagcattg accaggatga gttctgggcc      360

tttagctacg atgaaatggc taggtttgac ttgccagcag ttataaactt cattctgcag      420

aaaacgggcc aagagaagat ttactacgtt ggatattccc agggtactac aatgggattt      480

atcgcctttt caactatgcc tgaactggct cagaagatta aaatgtactt cgccctggcc      540

cctatcgcca cagtgaagca tgctaaaagt cctggaacaa agttcctcct gctgccggat      600

atgatgatca aaggactctt tggtaaaaaa gagttcttgt accagacaag attcctgagg      660

cagctcgtaa tctatctctg cgggcaggtg attcttgatc agatttgctc taacataatg      720

ctcctgctgg gcgggttcaa cacgaacaat atgaacatgt ctagagcttc agtttatgca      780

gctcacacac ttgcagggac tagtgtccaa aacatcttac actggagcca ggccgtcaac      840

agcggagagc ttcgcgcttt tgactggggg tcagagacca agaacctcga gaaatgcaat      900

cagcccaccc ctgtccggta tagagtcagg gatatgacgg tccctactgc tatgtggacg      960

gggggacagg actggctctc aaatcctgag gacgtgaaga tgctcctgag cgaggtgacg     1020

aacctgatct accacaaaaa tattcctgag tgggctcacg tcgactttat atggggctta     1080

gacgcacccc accgaatgta taacgagatt atacacctta tgcaacagga ggagactaac     1140

ctcagtcaag gtaggtgtga agccgtcctc                                      1170


<210>  4673
<211>  1140
<212>  DNA
<213>  Homo Sapiens

<400>  4673
ggcggatttt tggatcttga aaacgaggta aatcctgaag tgtggatgaa cacatcagag       60

attatcatct ataatggtta tccgtctgaa gaatacgagg tcaccacaga ggatggctat      120

atactcctcg tgaatcgcat cccttatggc agaactcacg cacgtagcac tggtcccaga      180

ccagtcgtgt atatgcagca tgcactgttt gccgataatg catactggct tgagaattat      240

gctaatggat ccctcggatt tttgttagca gatgcaggat acgatgtctg gatgggcaac      300

agtcgaggca atacatggtc cagacgtcac aaaaccttga gcgaaactga cgagaagttc      360

tgggcattct cctttgacga aatggctaag tatgatttac cgggggtaat cgactttatt      420

gttaataaga ccggacagga gaaactttat ttcatcggtc attctctggg gaccacaatc      480

gggtttgtgg cctttagcac catgcccgag ttagcacaac ggattaagat gaatttcgcc      540

ctcgggccta cgatatcctt caagtaccct acgggcatct tcactagatt ttttctgctg      600

cccaacagca taattaaagc cgtgtttgga accaaaggct tttttttgga ggataaaaag      660

accaagatcg cctctactaa gatctgtaac aacaaaatct tatggttgat ctgttccgaa      720

tttatgtctc tctgggccgg aagcaacaag aaaaacatga accagagtag gatggacgta      780

tacatgagcc atgcaccaac tggttcttcc gtccacaata tcctgcatat taagcagctt      840

tatcactccg atgaatttcg cgcctatgac tgggggaacg acgcggacaa tatgaaacat      900

tacaatcagt cccatccccc catctatgac ctcacagcca tgaaagtccc gacggccatt      960

tgggccgggg gacatgacgt actggtcaca ccacaagacg tggcccgtat cctgccccaa     1020

atcaagtcac tccactattt caaactttta cccgactgga accatttcga ctttgtttgg     1080

ggcctggacg cacctcagcg catgtactct gagataattg cccttatgaa agcttatagt     1140


<210>  4674
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  4674
agccctggtc ccaaagatgg cagccaaacc gaaaagaccc cttccgcaga tcagaatcag       60

gagcagttcg aagaacactt tgtggcttcc agtgtagggg aaatgtggca agtcgtcgat      120

atggcccagc aggaggagga ccagagttca aaaaccgctg cagtgcacaa gcatagtttt      180

cacctgagct tctgctttag cctggcaagc gtgatggtgt tctctggcgg tccattgcgt      240

cgcacctttc ccaacatcca attatgcttt atgctcaccc at                         282


<210>  4675
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  4675
ggacctagcg tgcaggaatg ctaccactcc aatggtcaga gctaccgcgg tacatacttc       60

actaccgtta ctggacgcac ctgtcaagca tggtcatcca tgaccccaca tcagcattct      120

cgaacacccg agaaataccc aaacgacgga ctcatcagta attactgtag gaacccagat      180

tgcagcgcgg gtccctggtg ttacaccaca gacccaaatg tgcgctggga atactgcaat      240

cttacaagat gcagcgatga tgaaggcacc gtgttcgttc ctctgacagt gattcctgtt      300

cccagtctgg aagacagctt tattcaggtg gca                                   333


<210>  4676
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  4676
ggatacggac cgcagaagaa attgaacctg agccacaaag ggatagggga gccttgccgg       60

cggcatgagg agtgtcagtc taactgttgc accataaaca gcctcgctcc gcacacatta      120

tgcactccca aaaccatctt tctgcagtgc ctgccatgga ggaaaccgaa cggttacaga      180

tgcagccacg atagcgagtg tcaatctagc tgttgcgttc gaaataacag cccccaagaa      240

ttgtgtaccc cacagtcagt gttcctgcag tgtgtccctt ggcgtaagcc caacggtgac      300

ttttgtagct cacaccagga atgtcatagc cagtgttgca tccagctgag ggagtactcc      360

ccgtttcgat gcatcccccg cacagggata ctcgctcagt gtctgccact c               411


<210>  4677
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  4677
atgagacacg aagagttgct cactaagaca tttcaggggc ccgcagtcgt ttgtggtaca       60

cccacgtcac atgtctatat gtttaagaat ggcagcggcg atagtggtga ctcttccgaa      120

gaggaaagcc accgcgtggt cctgagaccc agaggaaagg aacgccataa gagcggcgtg      180

catcagccgc cccaggccgg agccggcgac gtcgttctgc tgcagagaga acttgcccag      240

gaggattcac ttaacaaact cgccttacag tacggatgca aggtagctga tattaagaaa      300

gtgaataact tcatcaggga gcaggactta tatgcgctta aaagtgtgaa aatccccgtg      360

cgtaaccatg gtattcttat ggagacccat aaggagctca agcctctgtt gtcacctagc      420

tcagaaacca ctgtgacagt tgagctgccc gaagctgaca gagctggcgc cggcacggga      480

gctcaggcag ggcagcttat ggggttcttc aaaggcattg accaggatat cgaaagggcc      540

gtccagtcag aaatcttcct tcacgagtca tactgcatgg atacctctca tcagcccctg      600

ctccccgccc cacccaagac cccgatggat ggcgccgact gcggaatcca g               651


<210>  4678
<211>  780
<212>  DNA
<213>  Homo Sapiens

<400>  4678
tctccaacta tcttctatcg agactgttgg atccggcgct ttccaggtct cttgataaat       60

ctggaagagt cccaaaaact cggcgctcag tttttgaagt actacagcga gtccacgggg      120

cagaaatgca gcaggtcttg ctgcctgcgg aaagacgtaa gctgcaatct ggccgtgttc      180

taccacagtc ccatccatga caatatcaac tgcctgcatg tacactgccc caccctcgaa      240

agttgtatcc tggaaccagg gacctccgca atcctctata atatcaccga cggtatcgac      300

ccagacctcc tggtatttga acagagtccc acgtatctga atactaggtc ctctagcaac      360

aggtgggaca ggttgcgcat cctgaaggct atgaacttag ataagcaaac aactactatt      420

aacggcatgc tgcctagcac cgaggccccc agttctacga cacatcagga tctggtggtg      480

aacacaaact ctacaagtta cagtaaagag cttactacag acttctgggc tcgtttcaca      540

tctctcaacg agtccattac aacaaaaatc aataaggtgt caccctcaac agattttata      600

tccaacccag acaacaaaac aatttcacca ttctttgagc ccatcgacac caaactttct      660

cacatgcccg taccacccgg gcttaattcc tcaaaacaac tgctgaataa gactaagggt      720

tacaatagca gaaaccacac aagtgccaat gaagatgagg taagtgtgac aagtaagaca      780


<210>  4679
<211>  954
<212>  DNA
<213>  Homo Sapiens

<400>  4679
cagggtctta cccagactcc cacagagatg cagcgtgtat ctttgcggtt cggaggacca       60

atgaccagat cctaccgttc aacagcgagg acgggactcc caaggaagac taggattata      120

cttgaggatg aaaatgatgc tatggccgac gcagatagat tggcaggccc agcagccgcc      180

gagttactgg ctgcaactgt ctcaacagga ttcagcagga gttctgccat caacgaggag      240

gacggcagtt ccgaagaggg tgtggtaatt aatgccggga aggatagtac ttctcgcgag      300

ctccctagcg cgacacccaa tactgcggga agtagcagta ctagatttat cgccaacagc      360

caggagcccg agattaggtt gacctcaagc ctgccaagat cacccgggcg gtctacagaa      420

gacttgcctg ggagtcaggc taccctgtca cagtggagta ctcctggaag cactcctagc      480

agatggccga gcccatcacc caccgctatg ccgagccctg aggaccttag actggtgctg      540

atgccctggg gcccttggca ctgccattgc aagtcaggca ccatgtccag aagtagatcc      600

ggaaagctgc acggactgtc cgggaggctg cgagtaggcg cactcagtca gctgcgcaca      660

gagcataagc cttgcacgta ccaacagtgc ccctgtaata ggcttcgtga ggagtgccca      720

ctggacacat cactgtgcac agataccaat tgcgctagtc aaagcacaac atccaccaga      780

actaccacaa ccccatttcc tactatacac ctcagaagca gtccgagctt gcccccggca      840

tccccgtgcc cggcccttgc tttctggaag cgggtgagga tcggcttgga agacatttgg      900

aatagtctta gtagcgtgtt tacagaaatg cagccaatcg accgaaacca acgc            954


<210>  4680
<211>  810
<212>  DNA
<213>  Homo Sapiens

<400>  4680
gggtacagcg aagaacgatg ctcctggaga ggctctggac tgactcaaga acccggcagt       60

gtgggacagc tggctttagc atgcgccgag ggtgccgtag agtggctgta tcccgctggc      120

gctctgaggc tcactttagg gggccctgac ccacgtgcaa gacccggcat cgcttgtctt      180

aggcctgtgc ggccttttgc tggagcacaa gtctttgccg agcgggccgg cggtgccttg      240

gaactgctgc tcgcagaggg acctggccca gcaggtggaa ggtgcgtgcg ttggggccca      300

cgcgagagac gagccctctt tttacaggcg actcctcatc aggacatctc aagacgggtc      360

gctgcatttc gtttcgagct ccgggaggac gggagaccag agctcccacc ccaggcacat      420

ggtttgggcg tggacggagc ctgtcgtccc tgtagtgacg ccgaactgct gctggcagcc      480

tgcacttccg attttgtaat ccatggcata atccatggcg ttacacacga cgttgagctt      540

caggagagcg ttattaccgt ggtggccgcc cgggttttga gacagacccc acctctgttt      600

caggcagggc ggagtggcga ccaggggctg acatccatac gaacacctct tcgttgcggc      660

gtacaccctg gtcccggcac attcctcttc atgggttggt caaggttcgg cgaagccagg      720

ttgggctgcg cccccaggtt tcaagaattc cggagagctt acgaagcagc ccgcgcggct      780

cacttacacc cctgtgaagt ggcccttcac                                       810


<210>  4681
<211>  798
<212>  DNA
<213>  Homo Sapiens

<400>  4681
cagtattcca gcgatcggtg ttcctggaaa gggtccggac tgactcacga ggctcatagg       60

aaggaagtcg agcaggtcta cttgaggtgt gccgccgggg cagtcgagtg gatgtaccca      120

accggagccc tgatcgtcaa cctccgacca aacacattct ctccagcacg acatctgacc      180

gtgtgtataa ggagcttcac cgatagctct ggggcaaaca tttatctcga gaaaacaggc      240

gagctgaggc ttttagtccc agacggggac ggacgccctg gcagagtgca gtgtttcgga      300

ctggagcagg gaggtctgtt tgtggaagcg acaccgcagc aggatatcgg aaggcggact      360

acgggcttcc agtacgagct tgtgcgccgg cacagagcct ctgacctgca tgaactttct      420

gccccctgta ggccctgctc agacacggag gtgctcttgg ctgtttgcac aagtgacttc      480

gctgtcaggg gctcaattca gcaggtgacc cacgagcctg agcgtcaaga ttctgccata      540

cacctcaggg tgagccgcct ttatcgacag aagtcacgtg tatttgagcc agttcctgaa      600

ggcgatggcc actggcaagg gagagtgcgg accctcctgg agtgcggcgt ccgccccgga      660

catggcgatt ttctcttcac aggccacatg cactttggag aggccaggtt gggatgcgcc      720

ccccgcttca aggacttcca gcgcatgtat agggacgccc aggagcgcgg ccttaacccc      780

tgtgaggtgg gtacagat                                                    798


<210>  4682
<211>  1011
<212>  DNA
<213>  Homo Sapiens

<400>  4682
tgtgccgagc tgagacgggc aggtccaggt tcccccacaa ggagcgcacc ccctggacca       60

gcctggaggc ctcccgggcc acacctgccg cctgcacccg gccagccgag aggggcctcc      120

aggcggcagg tgacctatgt gagaagtgga cgccgcgctc caccaggagg cggggggtct      180

gggacgcctg aacctggctg ttgcgctccg cggggccgtc cccggcgtaa gggcccaagg      240

tggcacatcg acctgcagcc ctgggcgggg agtgctcaat ccctcgacga ggaagcctgg      300

cggtttctgc gctatatctc tactacacag atcgcatgta atcacatgaa tacggacagc      360

ctggctacag acagttctcc aactcacaag ccttggagcg tgtgccttga cgatcggttc      420

aacctggccc accagatccg aaacaaacaa tgtagactct actcattggg tctgggctcc      480

gatgataccc attttgaggt gagcatggcc aacaacggct gcgaagttca ccgcttcgat      540

ccttcagtga agtcagccca tatcttggag tcccaacact tatggtatca tcggctcagt      600

atcgactggc gggaccctca ccctgcagtt gccgcacaga aacctcactc aaatactcga      660

aagctcggga gcatcctgaa tgagttcgga caccataaga tagatgtcct caaggccgat      720

ctggaatctg ccgagtggaa agtcctggag aatctcatct tagaggatgt cctggagcaa      780

ataggacagc tgatttttga aattcacctc cattggccag gttttgaggt gtccggcagc      840

gattcaagcg ttgttagatt ttggtactcc ttgcttaaag agctcgaaca gaaagacttc      900

cggctctttc actcctataa agatctgagc aagccccaac ttttcttaaa gaaagacatc      960

tttaatgctt catcttgtta caccctctcc tgggtcaaca ccaggtggaa g              1011


<210>  4683
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  4683
ctcctgggat gctggcagcc tctgtgcaaa agctactttc cctacctcat ggctgttctg       60

acccccaagt caaataggaa aatggagagc aagaagcggg aactcttctc ccagattaaa      120

gggctgacgg gggcctcagg caaagtcgcc ctgctggagc tggggtgtgg caccggagcc      180

aattttcaat tctatcctcc tggctgtcgc gtgacatgtc ttgatcccaa ccctcatttc      240

gaaaagttcc tgaccaagtc catggcggag aacagacatc tccagtacga gcggtttgtc      300

gtcgcaccag gcgaggatat gcggcagctg gctgatgggt ccatggatgt ggtggtgtgt      360

accctcgttc tgtgcagcgt gcagtcaccc cggaaggtgc tgcaagaggt ccgccgggtg      420

ttgagaccag gcggggtgct gttcttctgg gaacatgtcg ctgagccata cggtagttgg      480

gcgttcatgt ggcaacaggt ctttgaaccg acctggaaac acattggtga cggctgttgc      540

ctgacaagag aaacctggaa ggaccttgag aacgcccagt tcagcgagat ccagatggaa      600

agacaacctc cacccttaaa gtggttgccg gtcggtcccc atatcatggg caaggctgtt      660

aag                                                                    663


<210>  4684
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  4684
cagctgcagg ccgcaccccc cagcggcgca agtcactccc ccctgccagc cgggggctta       60

acaactacga caactactcc caccatcacc accagccaag cagcagggac tcccaagggg      120

caacaggagt caggagtgtc cccgtccccc cagtctacct gcggcggact cctgagtgga      180

cctcggggct ttttctctag cccaaactat cctgaccctt atccacctaa tacacactgc      240

gtgtggcaca tccaggtagc caccgatcat gccatccagc tcaaaattga ggcactttct      300

atcgaatccg tggcctcatg tctgttcgat cgccttgagt tgtcaccaga gcctgagggg      360

cctttgctcc gcgtgtgcgg gcgcgtgcct cccccaacac tgaacacgaa cgcctcacac      420

ctgctggtgg tgtttgtttc cgattccagc gtcgaaggat tcgggttcca tgcgtggtat      480

caggccatgg cccccgggag aggctcatgt gcacatgacg agtttcgatg cgaccagctc      540

atttgcctcc ttcccgattc cgtttgtgac ggctttgcca attgtgccga tggcagtgac      600

gagaccaact gttccgcgaa atttagcggt tgcggaggca accttacggg tctccagggt      660

acgtttagta caccatctta cctccagcag tatccccatc aattattatg tacctggcac      720

atatccgtgc ctgcaggcca tagtatcgag ctgcaatttc ataacttcag cttggaggct      780

caggacgagt gcaagttcga ttacgttgag gtctacgaga cgtcttccag tggtgccttt      840

agcctgctgg gccgattttg cggtgcagag cccccacctc atctggtgtc cagccatcat      900

gaacttgctg tgttgttccg aactgaccac ggtatttcct ccggaggatt ctccgccaca      960

tacctcgcct tcaacgcaac tgagaacccc tgcggaccga gcgagctctc ttgccaagcc     1020

ggaggctgca aaggagtgca gtggatgtgc gacatgtggc gcgactgtac cgacgggtcc     1080

gacgataatt gcagtggacc cctgttccct ccccccgagc ttgcttgtga gccagtgcag     1140

gtggaaatgt gtctgggtct tagttacaat accactgcct tcccgaatat ctgggtgggt     1200

atgattactc aggaagaagt cgttgaggtg ctcagcggtt acaagtctct tacctccctt     1260

ccatgttatc agcattttag acggctgctg tgcggactgt tagtcccacg gtgtactccg     1320

ctgggttcag tacttccccc atgccgaagt gtatgtcagg aggccgaaca tcagtgccag     1380

tctgggctgg ccctgctcgg gaccccctgg ccattcaact gtaatcgact gcccgaggct     1440

gcagacttag aagcatgcgc ccagccc                                         1467


<210>  4685
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4685
tatgaatccc acgaaagtat ggagtcctac gagttgaacc catttatcaa ccgaaggaac       60

gccaatacct tcatttctcc acagcagaga tggcgggcca aggtccagga gcgcatacgc      120

gaacggagca agccagtcca tgaactgaac agagaagctt gtgacgacta tcgcttgtgc      180

gaaaggtacg caatggtgta tggatataat gctgcgtaca atcgctactt c               231


<210>  4686
<211>  1173
<212>  DNA
<213>  Homo Sapiens

<400>  4686
ttcgtgctgt ctggtggaag gtgggaaaag acagacctga cctaccgcat cctgcgcttc       60

ccatggcagc tggtgcagga acaagtcaga cagacgatgg ctgaagccct gaaggtctgg      120

agcgacgtta cgccactgac tttcaccgag gtgcatgagg gtagagctga tatcatgatt      180

gactttgcta gatactggca cggagacgac ctgcccttcg acgggcccgg tggcattttg      240

gcacacgcct ttttcccaaa aactcacagg gagggagacg tacactttga ttatgacgag      300

acatggacca ttggtgatga tcaagggacc gacctgctgc aggtagccgc ccacgagttt      360

gggcatgttc tgggtctgca gcacaccacc gccgcaaaag ctttgatgag tgcgttctac      420

acttttcggt acccactgtc cctgagcccc gatgactgta ggggggtgca gcacctctac      480

ggccaaccct ggcccacagt gaccagtcgc acaccagccc tgggcccaca agcgggcatc      540

gacacgaacg aaatcgctcc actggagcca gacgcccccc cagatgcctg tgaagctagc      600

ttcgacgcag tgagtaccat ccgaggcgag ctgttcttct ttaaggccgg ctttgtgtgg      660

cggcttcggg gaggccagct gcaacccggc tacccagccc tggccagccg acactggcag      720

ggcctgcctt cccctgtgga cgcagctttc gaggatgctc aagggcacat ctggttcttt      780

cagggagcac agtactgggt ctatgatggg gagaagccgg tgctgggtcc ggctccgctc      840

accgagttgg ggctggtgag gtttcctgta cacgctgctc tggtctgggg acccgaaaag      900

aataagatct acttctttcg cggaagagac tattggcggt ttcacccaag cacccgacga      960

gtggattcac cggtaccacg gagagccacc gactggcggg gggtgccttc cgagatcgat     1020

gctgcctttc aagacgccga tggatatgcc tacttcctgc gcggccgcct gtactggaaa     1080

ttcgatcccg tcaaggtgaa agcactggaa ggcttcccaa gactggtggg gccagatttt     1140

ttcgggtgtg ccgaacctgc taacactttt ttg                                  1173


<210>  4687
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  4687
agccccaggg cacccctctc cctgagtagg agaggctggc agcctagggg atatcctgat       60

ggcggagccg ctcaggcgtt ctctaaacgc acgttatctt ggcgcctgct gggagaggca      120

ctgagttccc agcttagcgt tgccgatcaa agacgaattg tggctcttgc gttccggatg      180

tggagcgagg tgactcctct ggactttaga gaggatctcg cagcacccgg ggctgccgtg      240

gacataaaac tgggattcgg gaggggcaga catctgggct gtcctcgagc ttttgacgga      300

agtggacagg aattcgccca tgcgtggaga ctgggggaca ttcactttga tgacgacgaa      360

catttcacgc cgcccacatc cgacaccggc atatccctgt taaaggtggc agtgcatgag      420

atcgggcatg tcttgggcct gccacacacc tatcgcaccg gatctatcat gcagccaaac      480

tatataccac aggaacccgc gttcgagctt gattggtccg atcggaaagc aatacaaaag      540

ctgtacggca gctgcgaagg ttcattcgac acagcattcg actggattag gaaagaaagg      600

aatcagtatg gggaagttat ggtgcgcttc tcaacctatt tcttcaggaa cagttggtat      660

tggttatacg agaatcgtaa taataggacc cgctacggag atcctattca gatcttgacc      720

ggttggcccg gaattccaac tcataatatc gacgcttttg tgcacatttg gacttggaaa      780

agagatgagc ggtacttctt tcagggtaat cagtactgga ggtacgattc cgataaggat      840

caggcactca ccgaagacga gcagggaaag agctatccca aactgatcag cgaggggttc      900

ccggggattc caagtccttt agacactgca ttttacgatc gcaggcagaa gctgatctac      960

ttcttcaaag agagcctggt gtttgctttc gacgtgaacc gcaatagggt tctcaatagt     1020

taccctaagc gaattactga ggtgtttccc gctgtcatcc cacagaatca ccctttccgt     1080

aacattgact cagcgtacta cagctacgcg tataactcta ttttcttctt taaaggaaac     1140

gcctattgga aagttgtaaa tgacaaggat aagcagcaaa actcatggct gccggcgaat     1200

ggactgttcc caaagaaatt catctccgaa aagtggtttg atgtttgcga tgtccacatc     1260

agtactttaa acatg                                                      1275


<210>  4688
<211>  1296
<212>  DNA
<213>  Homo Sapiens

<400>  4688
tacgccctca gcggctctgt ctggaaaaag agaacactga cctggcgtgt gaggtcattt       60

ccccaaagta gccaactcag tcaagaaaca gtcagagtcc tgatgagcta cgccttaatg      120

gcctggggca tggaaagcgg actgaccttc cacgaggtag actctccaca aggtcaggaa      180

cctgacattc tgatcgactt tgctagagca ttccaccaag actcttaccc ctttgatggc      240

ctcggcggca cgttggccca cgcattcttt ccgggcgaac accctatctc tggcgatact      300

cacttcgacg atgaagaaac atggacattc ggctccaagg acggggaagg gactgacctg      360

tttgccgtcg ctgttcatga gttcggtcac gcgctgggtc tcggacattc ctcagcgcct      420

aatagcatca tgagaccttt ctaccagggc cccgtgggtg atcccgacaa atatcgactg      480

agtcaggacg acagggacgg cctgcagcaa ctttacggta aagcccctca aacgccatat      540

gataagccta ccaggaaacc actcgcccca cctcctcaac ctccagcatc accaacccac      600

agccccagtt tcccaatccc cgatcgatgc gaagggaact ttgatgcaat agctaacatc      660

cgtggggaga cttttttctt caaggggccc tggttctggc gactccagcc cagcgggcag      720

cttgtctcac ctcgccccgc gcggttgcat aggttctggg aaggccttcc ggcccaagtg      780

cgagtggtac aagcagcata tgctcgccat agagacggtc gtatcctgct cttctctggg      840

cctcagtttt gggtttttca ggaccgacaa ctcgaagggg gagcgagacc cctcaccgag      900

ctgggactgc caccaggaga agaagttgat gcagtgttct catggcctca gaacgggaag      960

acttaccttg ttagaggccg ccaatactgg cggtacgacg aagctgctgc ccgacctgat     1020

ccaggatacc ccagggacct gtctctttgg gagggagcgc ccccatctcc agacgatgtg     1080

acggtcagca atgcaggcga cacttacttc ttcaagggtg cgcactactg gagatttccc     1140

aagaacagta tcaaaacaga accggacgct ccacagccta tggggccaaa ctggctggac     1200

tgccctgctc cgagtagtgg gccaagagca ccccgacccc ctaaggccac ccctgtcagc     1260

gagacatgtg attgtcagtg tgaactgaac caggca                               1296


<210>  4689
<211>  1449
<212>  DNA
<213>  Homo Sapiens

<400>  4689
gtccccctcc agagtaatcg gctgggtcca acctctcgac tgagatacag cagatttctg       60

gatccgtcca acgtgatctt tttgaggtgg gatttcgacc tcgaagctga gattatctct      120

ttcgaactcc aagtccgaac cgcaggttgg gtaggattcg gagtcacgaa cagatatact      180

aatgtggggt cagacctggt ggtggggggc gtgttgccca atggcaatgt gtacttcagt      240

gaccaacatc tggtggagga agacaccctg aaagaggatg gcagtcagga cgctgagctt      300

ctcggtttga ccgaggacgc ggtgtatact acaatgcact tcagccggcc attcagaagt      360

tgtgatcccc atgatctgga tataacctct aacactgtaa gagtgctggc agcgtatggt      420

ttagatgata cactcaagct gtacagagag agaacgttcg tgaaatcaat ttttctgttg      480

caggtggtac atcctgacga tctggacgtt cccgaggaca ctataatcca tgacctggag      540

atcactaact ttctgattcc agaggatgat acgacgtatg catgcacatt cctgcctctg      600

cccatcgtgt cagagaaaca tcacatctat aagtttgaac ctaagctggt ctatcacaat      660

gagactacag tacatcatat tctggtctac gcctgtggca acgccagcgt gttgcccaca      720

ggcatatcag actgttacgg cgccgatcca gctttctcac tgtgctccca ggtgatcgtg      780

gggagcgccg tgggcggcac aagctaccag tttcccgacg acgtgggcgt ttccatcggg      840

actccccttg acccacagtg gattttggag attcactaca gtaatttcaa caatctgcca      900

ggcgtgtacg atagcagcgg tatccgcgtc tactacacgt ctcaactgtg taaatacgac      960

actgacgtcc tgcaactcgg gtttttcacc tttccgattc acttcattcc ccccggggcc     1020

gagtccttta tgagctacgg tctctgccgc acagaaaagt tcgaggaaat gaacggcgcc     1080

ccaatgccag acatccaagt gtacggctac ctgctgcaca cacacctggc cggtagggcc     1140

ctccaggctg tgcaatatcg gaatggcact cagcttcgca agatttgcaa ggatgatagc     1200

tacgatttca atctgcagga gactagggac ctgccaagtc gtgtggagat taagcccgga     1260

gacgagctgt tggtggaatg tcattaccag actctggatc gggacagcat gacttttggc     1320

ggtccttcca ccataaatga aatgtgcctc atcttcctgt tctattatcc ccaaaataac     1380

attagttctt gtatgggcta cccggatatc atatacgttg ctcatgagct cggagaggaa     1440

gcaagtgag                                                             1449


<210>  4690
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  4690
agcaaatgct atttccaagc ccaagcgcct tgccactacg aaggcaagta tttcacatta       60

ggagagagct ggctcagaaa agactgcttt cattgcacat gtctgcaccc agtcggagta      120

ggctgttgtg atacctctca acaccccata gatttccccg ccggttgcga ggtacggcaa      180

gaagcaggaa catgccaatt cagcctcgtg cagaagtccg atcctcgcct cccatgtaag      240

gggggcggac ccgatcctga gtggggctct gctaacacgc ctgtgcccgg cgccccagcc      300

cctcacagca gc                                                          312


<210>  4691
<211>  1257
<212>  DNA
<213>  Homo Sapiens

<400>  4691
accacttttc aagagtacca aaagacagga gagctgtcaa cctccgacca catatttccg       60

ctcacacctg gccttgttta tagcattccc tttgatcata ttgttctgca ctctgggcag      120

aggccgccag aactgcctaa gtccactgag attcatgaac agaaaaggca ttgtaatact      180

actaggcaca gcaaacctac tgacaaaccg accgggaatt ccaaaactat cgatcacaaa      240

agttcaactg ataatcacga ggccccacct acctccgaag agaacagcag caatcagggt      300

aaggacccaa tgatacgtaa tcagcggtca gtggacccag ccgacagcac cacaacgcat      360

aaggaatctg caggaaaaaa gcatattact cctgccccaa aatctaaaat caactgccga      420

aaaagcacga ctgggaaatc tacggtgact cgaaaatccg ataagacggg ccgacccctg      480

gaaaagtcca tgtccacatt agacaagacg tcaactagta gccataagac tacaacctca      540

tttcataact ccggaaacag ccagactaag cagaaaagca caagttttcc tgagaagatc      600

acagctgcat caaagacaac atacaaaact accggcacac ccgaagagtc agaaaagacc      660

gaagacagcc gcactaccgt ggcctcagat aagctgctca ctaagaccac caagaatatt      720

caggagacca tctcagccaa cgagttaaca caatcactgg ccgagcctac tgagcatggt      780

ggcagaacag ccaacgagaa caacaccccc agcccggcgg agcccaccga gaacagggag      840

cggaccgcca acgaaaataa gaaaaccata tgcactaaag gtaaaaacac cccggtgccc      900

gaaaagccta cggaaaatct cggaaacacc accctgacca cagagactat caaggcaccc      960

gttaaatcta cggagaatcc tgagaaaaca gctgcggtca ccaagacaat aaagccctct     1020

gtgaaagtta caggggataa aagcctgact acaacgtctt cacatctgaa caaaactgaa     1080

gttactcacc aagtccccac aggaagcttc actcttatca catcacggac taagctgtct     1140

tcaatcacct ccgaggcaac cggcaacgag agtcaccctt acctcaataa ggatggatct     1200

cagaaaggaa tccacgctgg ccagatgggc gaaaatgata gctttcctgc ttgggcc        1257


<210>  4692
<211>  993
<212>  DNA
<213>  Homo Sapiens

<400>  4692
tctcctcccg cagccccccg attcaacgtg agcctggact cagttcccga attgagatgg       60

ttacccgtgc tgcgacacta tgacctggat ctggtgcgcg cagcaatggc tcaggtcatc      120

ggggaccgcg tcccgaagtg ggtacatgtg ctgatcggca aagtggtcct ggagctggag      180

cggttccttc cacagccctt tacgggcgag atacggggca tgtgtgattt tatgaacctg      240

tccttggccg actgtctgtt ggtaaattta gcctacgaat ccagcgtgtt ctgcacatcc      300

attgtggctc aggacagccg tgggcatatc taccacggca ggaacctgga ctatccattc      360

gggaatgtct tgaggaaact taccgtggac gttcagtttc tgaagaacgg ccaaattgcc      420

tttaccggga caaccttcat cggatatgtc gggttatgga ctgggcaatc cccacataag      480

ttcacagttt ccggcgatga gcgcgacaag ggctggtggt gggaaaatgc catcgccgct      540

ttattccgta gacatattcc cgtcagttgg ctgattagag cgactctgag cgagtccgaa      600

aattttgagg ccgccgttgg aaagctcgct aaaactcctc tgatcgctga tgtgtactat      660

attgtgggag gcacctcccc gcgagaaggc gtagtgatta cacggaacag agatgggcca      720

gctgatatat ggccacttga ccccttaaac ggggcctggt ttagggttga gactaattat      780

gatcactgga aacccgcacc taaggaagat gatcgccgga catccgccat caaggctttg      840

aacgccaccg gtcaagcaaa cctgagcttg gaagcgctgt ttcaaatatt aagtgtggtc      900

cccgtataca acaattttac tatttacaca acagtgatgt ccgcaggcag cccagataag      960

tacatgacaa ggatccgcaa tccttcaaga aaa                                   993


<210>  4693
<211>  495
<212>  DNA
<213>  Homo Sapiens

<400>  4693
gcagctcccc ctcccattaa taaattggcc ctttttccag acaaaagtgc atggtgtgaa       60

gctaagaaca tcactcagat cgtgggacac tccggttgcg aagctaaaag tatccagaat      120

agggcatgcc tggggcagtg cttcagttac tccgtcccca acacttttcc tcagtccaca      180

gaatcactcg tgcattgcga cagttgcatg ccagcccaat ccatgtggga aatagtaacc      240

ctggaatgcc ccggtcatga agaggtaccg cgagtggaca aactggtgga gaaaatcctt      300

cactgctcct gccaggcgtg cggcaaggag cccagccatg agggcctgag tgtttacgtt      360

cagggtgaag acggaccagg ctctcagccc gggacccatc cccacccaca tcctcatcca      420

cacccaggcg gccagacccc tgaaccagaa gacccacctg gtgctccaca tacagaagaa      480

gagggggcag aagac                                                       495


<210>  4694
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  4694
acaaagaaag gaactgagaa gcaaactaca agtgaaactc aaaagtcagt ccagtgcggc       60

acatggacca agcatgcaga aggtggcatc tttacgtccc ccaattaccc aagcaagtat      120

cccccggaca gagagtgtat ctacatcatc gaagccgccc ctcgtcagtg catcgaactg      180

tattttgacg agaaatactc cattgaacca agctgggaat gcaagtttga ccacattgag      240

gttagagacg gcccattcgg gtttagcccc atcatcggca ggttttgcgg gcaacagaac      300

cctcccgtga taaaatcttc tggtcgattt ctgtggatta aattcttcgc cgacggcgag      360

ctcgagagta tgggtttttc cgcccgctat aatttcacgc ccgaccctga tttcaaggat      420

ttgggagcac tgaaacccct gccagcatgt gaattcgaaa tggggggctc cgagggaatt      480

gttgaaagca tccagatcat gaaagaggga aaggctaccg ccagcgaagc ggtggattgc      540

aaatggtaca ttagggcccc cccacgctcc aaaatttacc ttaggtttct tgactacgag      600

atgcaaaatt ccaacgagtg caaaagaaac tttgtggccg tctacgacgg atcaagttct      660

gtcgaagatc tgaaagctaa attttgtagc accgttgcta atgacgtcat gctgcgcacc      720

ggtctgggcg ttatccgtat gtgggcagac gaagggagcc ggaatagccg cttccaaatg      780

ctttttacct catttcagga gccaccttgt gagggaaata catttttttg tcactctaac      840

atgtgcatca acaatacttt ggtgtgtaat ggacttcaga actgtgtgta cccatgggac      900

gagaaccact gcaaagagaa acgcaagacc agcctgctgg accaactgac caataccagt      960

gggacc                                                                 966


<210>  4695
<211>  828
<212>  DNA
<213>  Homo Sapiens

<400>  4695
gcagtcaccc gctgtggctt tgcaactcgg ggagtggcag gacctggacc tatcggccgg       60

gagcccgacc ctgactcaga ctgggagcca gaagagagag aacttcagga agtggagagc      120

accttgaaac ggcaaaagca ggcaattagg tttcagaaaa ttcggcgcca gatggaggct      180

ccaggcgcgc cccctaggac ccttacctgg gaagccatgg agcaaattag atacctgcat      240

gaagagttcc cagagtcctg gagcgttcct cgcctggccg agggatttga cgtgagcacc      300

gacgtaatca gacgagtcct taagtccaag tttttgccca ccttagaaca gaaactgaag      360

caggatcaga aagtgctgaa gaaagccggt ctcgctcact ctctccagca cctgcgaggg      420

tccggtaaca caagcaaact cctccccgca ggccactccg tgtccgggag cctgctgatg      480

cccggacacg aggcgagcag caaggatcct aaccattcta cggctctcaa ggtcattgag      540

tccgacaccc accggacaaa caccccacgg cgacggaaag ggcgcaataa ggagatccag      600

gaccttgaag aatcattcgt gcccgtggcc gctcccctgg ggcacccccg cgaacttcag      660

aagtattcct ccgatagcga atctcctcgt ggtaccggat ccggcgctct gcccagcggg      720

cagaagctgg aggagttgaa agctgaggag cccgacaact tttctagcaa ggtcgtacag      780

agagggagag agtttttcga ctccaatggc aactttctct accgtatc                   828


<210>  4696
<211>  351
<212>  DNA
<213>  Homo Sapiens

<400>  4696
atgcctggag atagttcacc tggaactttg cctctctggg atgcctcatt gagtccacct       60

ctgggaccgg atcccggggg gtttagtagg gcatcccatg ctggcgacaa gtcccgccct      120

cccgctcctg agttgggctc tcctggcgct gtgagaccca gagtgggatc ctgcgcacct      180

ggaccgatgg aactgcgcgt cagtaacacc agttgcgaga atggtagcct gcttcacctc      240

tactgttcat ctcaggaagt cttatgtcag atagtcaatg acctttcacc cgaagtccca      300

tcaaatgcca cgttccactc ctggcaagag aggatccggc agaattatgg c               351


<210>  4697
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  4697
agtgagggac gaaagacctg gaggcggcgg ggacagcagc ctcctccacc tccacggacc       60

gaggccgcgc cagccgccgg acagccagtc gaatccttcc ctctggactt tacagccgtg      120

gaaggcaata tggacagctt catggcacag gtcaaatccc ttgcacaatc actctacccc      180

tgcagcgccc agcagcttaa cgaagacctc aggctccact tacttctgaa cacatccgtc      240

acttgcaacg acgggagccc ggcaggctac tatttgaagg agtcacgggg tagtagacgc      300

tggcttctct tcttagaggg cggctggtac tgtttcaatc gcgaaaattg tgattcccgg      360

tacgacacca tgagacgact gatgtcttcc agagattggc cgagaacaag gactggtaca      420

ggcatactga gcagtcagcc tgaagagaat ccttattggt ggaacgccaa catggtgttc      480

ataccctact gttctagcga tgtctggtcc ggcgccagca gcaagtcaga aaaaaatgaa      540

tacgccttta tgggagccct tatcattcag gaggtcgtca gggagctcct tggccgtggc      600

ttgagcggag caaaggtgct gttgctggcc ggatccagcg ctgggggcac tggtgtgctg      660

ctgaacgttg accgcgtggc agagcagctg gagaaactgg gctaccctgc cattcaggta      720

agagggctcg cggattctgg ttggttcctg gataataagc agtacaggca tactgactgc      780

gtggatacca tcacctgtgc acctacagaa gccatcagac gtggaatacg ctattggaat      840

ggcgtggtgc ctgagcggtg taggaggcag tttcaggagg gggaagagtg gaactgcttc      900

ttcgggtaca aggtgtaccc tactcttagg tgccccgtct ttgtcgttca gtggctcttt      960

gatgaagcac agctcacggt ggacaacgtt catcttacag gccagccagt acaggaagga     1020

ttgaggctgt atatccagaa tctgggtcgc gaattaagac acaccctgaa ggacgtccca     1080

gcgtctttcg cgcctgcgtg cttatcccac gagatcatca taaggagcca ttggaccgat     1140

gtgcaagtca aaggcacctc cctcccccga gcattgcact gctgggatcg ttctctgcac     1200

gatagtcata aggcatcaaa gactcctttg aagggatgtc ccgtccacct cgttgattct     1260

tgcccctggc ctcactgcaa ccctagctgc ccaacggtgc gggatcagtt tactggacaa     1320

gaaatgaatg tggcacagtt cttaatgcac atgggctttg acatgcagac tgtggctcag     1380

ccacagggac tggagccttc tgaactgctg ggtatgctgt ccaatggttc t              1431


<210>  4698
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  4698
gggcgaattg tgcgtggcca gactcaggac tccctctctc tgcacaacat tacattttgc       60

agggaccgtt acgccgagtg gcagacagtt gcgcagtgtc ccgttccaca gttttcaggc      120

aaagagccta gcgcatggaa gtggattctg ggccctgtag tcctgtatgc ttgcgagcga      180

attatccgct tctggcgatt ccaacaggag gtggtgatta caaaggtggt tagccatcca      240

tccggggtct tagagctgca catgaagaag aggggtttta agatggctcc agggcaatac      300

attctcgttc agtgccctgc tatttcctcc ttggagtggc atccttttac actgactagc      360

gctcctcagg aagatttttt ctccgtgcac atcagagccg ccggggattg gactgccgcc      420

cttctggaag ccttcggagc tgagggtcag gccttgcaag agccctggag cttgccgagg      480

ctggccgtag atggaccatt cggaaccgca ctgactgat                             519


<210>  4699
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  4699
cagcccaccc cagtgattaa tagcttggcc gtctatcgtc accgtgagac tgactttgga       60

gtgggagtgc gcgaccatcc tggacagcat gggaagacac cgagtccaca gaaattagac      120

aacctgataa taatcattat tggctttctg aggcgggaca ccttcaccat tctgttttgc      180

acatcttacc tgtgcgtttc cttcctgaag accattttct ggagccgtaa tggacacgat      240

ggttccaccg acgtgcaaca gcgcgcctgg cgctccaaca ggagcaggca aaagggcttg      300

aggtcaatct gcatgcacac aaaaaagagg gtgtccagct ttcgcggcaa taaaatcgga      360

ctgaaggacg tgattaccct gaggcgccat gtggagacca aggtgcgggc caaaatccgc      420

aagcggaagg tgacaactaa aatcaatcga catgacaaga tcaacggaaa gaggaagact      480

gctaggaagc agaagatgtt tcagagggct caggaactga ggagaagagc cgaggattac      540

cataaatgta agattccccc tagcgcgagg aaacctctgt gtaactgggt caggatggca      600

gcagcagaac accggcattc tagcggtctg ccctgctggc catatcttac tgccgaggcg      660

ctcaaaaata gaatgggtcg gcagccgccg cccccaaccc aacagcatag cattaccgac      720

aacagtctgt ccttgaaaac tcctcccgag tgtctgctgc accctctccc acccagcgtg      780

gacgacaaca tcaaggagtg cccactcgct cccctccctc caagcgtaga cgacaacttg      840

aaggaatacc tcctcgtgcc cctcccccca agtccactgc caccatccgt ggatgataac      900

ctgaaggact gcctgttcgt gcctctgccc cctagtccac tcccacctag cgtggatgac      960

aacctgaaaa cacctcctct tgctacccaa gaagccgaag cggaaaaacc tccaaagcca     1020

aagcgctgga gggtcgacga ggttgagcag tctccaaagc caaagcgtcg ccgggccgac     1080

gaggtcgagc agtcccctaa gcccaaaaga cagcgcgagg ctgaagccca acagttacct     1140

aagccgaagc gtcggcgact tagtaagctc agaactcggc attgtaccca ggcatgggca     1200

attaggatca acccgtgggt ggagaaaaag aaaaaaatca agaagcagaa caagacccac     1260

gcccccaaga ccaac                                                      1275


<210>  4700
<211>  1188
<212>  DNA
<213>  Homo Sapiens

<400>  4700
caacctaccc ctgtgattaa ctccctggcc gtatatcgcc atcgcgaaac tgatttcgga       60

gtgggggtta gggaccaccc cgggcagcac gggaaaactc cctctcccca aaagctcgat      120

aatttgatta tcattataat cggattcctc cgtagatata ctttcaacgt tttgttttgt      180

acttcttgtc tctgtgtcag ctttctgaaa acaatctttt ggagcaggaa cggccatgat      240

ggcagcatgg acgtgcagca gcgcgcatgg cgctccaatc gcagccgcca gaagggactg      300

agaagcattt gcatgcatac aaaaaagagg gtatcatcat tccggggcaa taagatagga      360

ctgaaggatg tgatcactct tcgcaggcat gtggaaacca aggtccgcgc caaaatcagg      420

aaacgtaagg taaccacaaa aataaacaga cacgacaaga ttaatgggaa aagaaagact      480

gcacgaaaac agaaaatgtt ccagcgggcg caagaactcc gtcgaagggc cgaagattac      540

cataagtgca agatcccacc aagcgcaaga aagcccctct gtaactgggt taggatggct      600

gccgcagaac attgccactc ttccgggctc ccatattggc tctatctgac tgctgagacg      660

ttaaaaaatc ggatggggcg gcagccccct ccacccacac agcagcactc aattaccgac      720

aacagtctct ctctgaaaac cccccccgaa tgccttctga ctcctctccc gccaagcgtt      780

gacgacaata tcaaagagtg tcccctcgca cccctgcctc catctcctct ccctccttct      840

gtggatgata atttaaagga gtgtcttttt gtgcccctgc ctcccagccc actgccacca      900

tccgttgacg ataacttgaa ggagtgcctg ttcgtgccac tgccaccctc accactccca      960

cctagcgttg atgacaatct gaagacgccg cccctggcta cacaggaagc ggaggttgag     1020

aaaccaccta agcctaaacg gtggagagtc gatgaggtag agcagtcccc aaagccaaaa     1080

cgacaacggg aggctgaagc acagcagctc ccaaagccca agcggaggcg attaagcaag     1140

ttaagaacac ggcattgtac acaagcctgg gctatccgca tcaaccca                  1188


<210>  4701
<211>  324
<212>  DNA
<213>  Homo Sapiens

<400>  4701
cacccccttg gcagtccggg ctccgcatca gacctggaga cttcaggact ccaggagcag       60

aggaaccacc ttcagggaaa gttatcagaa ctgcaggtcg agcagaccag cctcgaacca      120

cttcaggaga gcccccgccc aacgggagtg tggaagtccc gggaggtcgc taccgagggt      180

atcagagggc atcgcaaaat ggtcctctat accctgagag cacctcgctc cccgaaaatg      240

gtccagggca gcggatgttt cgggcggaaa atggacagaa tatcctcctc cagtgggctt      300

ggctgcaaag tgttacgcag acat                                             324


<210>  4702
<211>  1365
<212>  DNA
<213>  Homo Sapiens

<400>  4702
ggtggtgtcg gaggcggcgg cggcggcgcc ggtattgggg ggggccggca agagcgcgag       60

gcactcccac cccaaaaaat tgaggttctc gtcctcttgc cccaagacga cagctacctt      120

ttttctttaa cacgcgtcag acctgctatc gagtatgcgc tccggagcgt ggaagggaac      180

ggaacaggta gacgactcct tccgccaggt actcgttttc aggttgccta tgaggattct      240

gactgcggaa accgggcact gttcagtctg gtcgatcgag tggccgccgc ccgcggagca      300

aaaccggact tgatcttagg accagtatgc gaatatgcag ctgctcccgt tgccagactc      360

gccagtcact gggatctgcc catgctttcc gctggcgcgc tggccgccgg cttccaacac      420

aaggatagcg aatatagcca cctcacccga gttgctcccg cttatgcaaa gatgggcgag      480

atgatgcttg cactgttcag gcatcaccac tggagccgcg ccgccctcgt gtactcagat      540

gacaagctgg agcggaactg ttacttcaca ctggagggcg tgcacgaggt gtttcaggaa      600

gagggactgc acacaagcat atactcattc gacgagacta aagatctgga cttagaggac      660

atcgtgcgga acatccaagc tagcgagcgc gtggtgatca tgtgtgccag ttcagatacc      720

atccgatcca taatgttggt ggcccatcgg catggtatga ctagcgggga ctacgctttc      780

tttaacatcg aactcttcaa ctcaagcagt tacggcgacg gatcctggaa aaggggggac      840

aaacacgact ttgaggctaa gcaggcatat tccagccttc aaaccgtgac tttgctccgc      900

acggtcaagc cagagtttga gaagttctct atggaggtca aaagctcagt cgaaaagcag      960

ggcctgaata tggaggatta cgttaatatg tttgtggagg gcttccacga tgcaatcctc     1020

ctttatgtcc ttgccctcca cgaggtgctg agagctgggt atagtaagaa ggacggcggg     1080

aagatcatcc agcaaacatg gaacaggacg tttgaaggga ttgccggaca ggtgtccatc     1140

gacgcaaatg gggacagata cggagacttc tccgtgattg ctatgactga cgtggaagca     1200

ggcacacaag aagtgatagg ggactacttc ggaaaagaag gcaggttcga gatgcggcca     1260

aatgtaaaat acccatgggg ccccctcaag cttagaatcg acgagaacag gattgtcgaa     1320

cacacaaatt cctctccttg caaaagcagt ggaggcttag aagag                     1365


<210>  4703
<211>  267
<212>  DNA
<213>  Homo Sapiens

<400>  4703
gcaggaaaat gcgacgccgt gttcaagggc ttcagtgatt gtcttcttaa gcttggagat       60

agcatggcca attaccctca gggccttgac gacaagacaa acattaagac cgtatgtacc      120

tactgggagg actttcatag ttgcaccgta accgcactga cagactgcca ggagggcgca      180

aaagacatgt gggacaagtt gcggaaggag tctaagaacc tgaatattca gggctctctg      240

tttgaactgt gcggttctgg caatgga                                          267


<210>  4704
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  4704
gctcgcctgg gcgctaggcc ttgtgggctg cgggagctgg aggtacgcgt gtccgagctt       60

ggactgggct atgcaagcga cgaaacggtc ttgtttcgct actgtgcagg agcctgcgag      120

gccgccgcta gggtttacga cctcggcctt agacggctga gacagagacg gcggctgcgg      180

cgggagcggg ttcgcgccca gccctgttgc agacctaccg cttatgagga tgaggtgagt      240

tttctggacg ctcattctag gtaccacact gtgcacgaac tgtccgctcg agagtgtgcc      300

tgcgtc                                                                 306


<210>  4705
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  4705
gtcccccttg agcgtggggc cccgaacaag gaggaaacac ctgctaccga gtctcctgat       60

actggtctct attatcaccg ctacctccag gaggtgattg atgttctgga gaccgacgga      120

cactttcggg aaaagctgca ggctgcaaat gccgaggaca ttaaatccgg gaagctgagc      180

agagagctgg acttcgtaag tcatcatgta aggactaagc tcgacgagct caagcgacag      240

gaagtcagcc gccttcgcat gttactgaaa gcaaagatgg acgccgaaca agaccccaac      300

gttcaagtgg atcacctcaa tttactcaag caattcgagc acttggaccc acagaaccag      360

cacacgttcg aggcacgaga tttagaactt cttatccaga ccgccacgag agacctcgcc      420

cagtatgatg ccgcccatca cgaggagttt aagcgctacg agatgcttaa ggaacacgaa      480

cggaggcgat acctggaatc tttgggcgag gaacaacgta aagaggctga gagaaaactg      540

gaagaacagc agaggcgcca tagagaacac cctaaggtga atgttccagg gtctcaggct      600

cagctcaagg aggtgtggga ggaactggat ggattggatc cgaacaggtt caatcccaag      660

acattcttta tacttcatga tatcaattcc gacggcgttc tcgatgaaca ggaactcgag      720

gctttattca ccaaagagct ggagaaggtg tatgacccaa agaacgagga ggacgacatg      780

agagagatgg aggaggaacg cctgcggatg agagagcacg tgatgaaaaa cgtcgataca      840

aaccaggacc ggcttgtgac tctcgaggaa ttcttggcct ccacccagag aaaggagttc      900

ggcgataccg gagagggctg ggaaacagtg gaaatgcacc cagcatacac cgaggaggag      960

ttgcgcagat ttgaggaaga gctcgcagcc cgggaagccg aactcaatgc gaaagcccag     1020

cggctgtccc aggagacaga ggcattagga cgctctcagg ggagacttga ggcacagaag     1080

cgagagctgc agcaggctgt gctccacatg gaacagcgga aacagcagca gcaacagcag     1140

caagggcaca aggcccctgc agcccatcca gaaggacagt tgaagttcca tccggatacc     1200

gacgacgtgc cggtgcccgc ccctgcgggt gaccaaaagg aggttgatac ctctgagaag     1260

aagctgctgg aacgcctccc cgaggtcgag gtgccccagc acctt                     1305


<210>  4706
<211>  1188
<212>  DNA
<213>  Homo Sapiens

<400>  4706
gtccctattg atattgataa aacgaaggtc caaaatatcc acccagtcga atccgcgaaa       60

attgagcccc cagatacagg cttatattac gacgaatacc tgaagcaagt catcgacgtg      120

ttagagacag ataaacattt cagggaaaag ctccagaaag ccgacatcga ggaaataaag      180

tccggacggt taagtaagga gctggacctt gtatcccacc acgttcgcac aaagcttgat      240

gagctcaagc gccaggaagt gggacgcctg cgcatgctca tcaaagccaa gctggattcc      300

ctgcaggaca tcggcatgga tcaccaggcc cttctcaagc agtttgatca tctgaaccat      360

ctgaacccag acaagttcga aagcaccgat cttgacatgc tcatcaaagc tgccacttct      420

gatctggaac attatgataa aaccaggcac gaggaattta agaaatatga gatgatgaaa      480

gagcacgaga ggcgggaata tctgaagacc ctgaacgaag agaagaggaa ggaagaagag      540

tcaaagtttg aggaaatgaa aaagaagcac gagaatcacc caaaggtgaa ccaccctggg      600

tcaaaagacc agttgaagga ggtgtgggaa gagaccgatg gcttggaccc aaacgacttt      660

gatccaaaga ccttttttaa attgcacgat gtgaattctg acgggttcct ggatgaacag      720

gagctcgagg ccctctttac aaaagagctt gagaaagtct atgaccccaa gaacgaggaa      780

gatgatatgg tggagatgga ggaagagcgg ctccgcatga gggagcatgt catgaacgag      840

gtggacacca acaaggacag gcttgtcaca cttgaggagt tcttgaaagc caccgagaag      900

aaggagtttc tcgaacctga ttcctgggaa acccttgacc agcagcaatt ttttacagaa      960

gaggaactta aggagtatga aaatattatc gctcttcagg aaaatgagct gaaaaagaag     1020

gccgatgagc tgcaaaaaca gaaagaggag ctgcagcggc agcatgacca gttggaggcg     1080

cagaagcttg agtaccacca ggtaattcaa cagatggagc agaagaaatt acagcagggc     1140

atcccaccaa gcgggccagc tggcgaatta aagtttgagc cacatatc                  1188


<210>  4707
<211>  1200
<212>  DNA
<213>  Homo Sapiens

<400>  4707
atgatggatt tacgcaatac tccggccaaa tcactggaca aattcatcga ggattacctt       60

ttgcctgaca catgttttcg catgcaaatt aatcatgcca tcgacattat ctgcggcttc      120

ctgaaagaac gttgtttcag agggagctcc taccccgtgt gtgtatcaaa ggtcgtcaag      180

ggaggctcat cagggaaagg cactacactg aggggtagga gcgacgctga cctcgtggtg      240

ttcctgagtc cacttaccac attccaggat cagctgaata ggaggggaga atttattcag      300

gagatccgtc gccagctcga ggcttgtcaa cgcgaacgtg ctttcagcgt aaaatttgaa      360

gtgcaagccc ctaggtgggg taaccctagg gcgctgtcct tcgtgttgag ctccctgcaa      420

ttgggggaag gtgtggaatt cgacgtgctg cccgctttcg acgcactggg tcagctcaca      480

ggaggctata agcccaatcc acagatatac gttaagctca tcgaggaatg cacggatttg      540

cagaaggaag gcgaatttag cacttgtttt actgagctgc aaagagactt tctgaagcaa      600

aggcccacca aactgaagtc cctgatcaga cttgttaaac attggtatca gaactgcaaa      660

aaaaagctgg gcaaattacc tccccagtac gctctggaac tgctgaccgt gtatgcttgg      720

gagcgcggct ccatgaagac ccactttaac accgctcagg gattccgcac agtgctggag      780

ctggtgatca attatcagca gctgtgcatc tactggacca agtattacga cttcaaaaat      840

cccatcatcg aaaagtacct taggcgccaa ttgaccaagc caaggcctgt aatactcgac      900

ccagccgatc ccactggtaa cttgggtgga ggggacccaa agggctggcg tcagctcgca      960

caggaagcag aggcttggtt aaactaccct tgcttcaaga attgggatgg cagtccagtc     1020

agcagttgga ttcttctcgc cgagtccaac tccgctgatg acgaaacaga cgacccgaga     1080

agatatcaga aatatgggta tatcggcaca cacgagtatc cacacttcag ccaccgccct     1140

agtactttgc aggccgcttc tacaccacag gccgaagaag attggacatg cactattctg     1200


<210>  4708
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  4708
ttgtcattta cgcttgaaga agaggatatt actggtacat ggtatgtgaa ggctatggtg       60

gtcgacaagg actttcccga agacaggcgg cctaggaaag tgtccccggt taaagtgacg      120

gccctcggag gaggtaactt ggaggctacc tttactttta tgcgtgaaga tcggtgcatc      180

caaaagaaga tcctgatgcg caaaacagaa gagcccggca agttctctgc ctacggcgga      240

cgcaagctga tctatctgca agaacttccc ggtacagacg attacgtgtt ctattgtaaa      300

gatcagcgcc ggggaggctt acggtacatg ggaaagctgg tggggcggaa tcctaacaca      360

aatctggaag ccctggagga gtttaaaaaa ttggtccagc ataaaggact gtccgaagag      420

gatatcttta tgcctttgca gaccgggagc tgcgtcctgg agcac                      465


<210>  4709
<211>  1380
<212>  DNA
<213>  Homo Sapiens

<400>  4709
catccactcg acacaccaca tctcccccag gaactccctc ccggcctccc taacaatatc       60

aacataacat tctttagtgg gatgttcaag aatgtcgaat ctgtagctga aatcttcgat      120

tgccttggac cacactttac ttggcttcaa gctgtcttca caaactttcc tgtactgatc      180

caatttgtaa atggcatgaa gtgtgtggcc ggcttatgtc caagggactt cgaggactat      240

gggtgcacct gtaggttcga gatggaaggc ctccctgtgg acgagtctga ttcttgctgt      300

tttcaacaca ggcggtgcta tgaggaggca gctgaaatgg attgcctcca ggaccctgca      360

aagcttagta cagaggttaa ctgcgtgagt aagaaaatta tctgcgagag caaggataac      420

tgcgagcacc tgttgtgcac ctgcgataaa gcagccatcg agtgcctggc ccggtcatca      480

cttaattcca gcctgaatct gctggatact tccttttgtc tggcccaaac ccctgaaaca      540

accataaagg aggatctcac tacacttttg ccgcgggtgg tgcccgtcga gcccaccgat      600

accagcctga ccgccctctc tggagaagaa gctgggcacg atcaggaggg agtaggggcc      660

gcccgcgcca cgtcccctcc tggcagcgcc gagatcgtgg caacacgcgt taccgcgaag      720

attgttaccc tcgtgccagc tggaatcaag tcactgggcc ttgccgtgtc ctcagtcgaa      780

aatgatcctg aagaaactac cgagaaggcc tgcgacagat ttacatttct gcacctggga      840

tcaggggata atatgcaagt gatgcctcag ctgggagaaa tgctgttctg tctgactagc      900

cggtgtcctg aggaatttga gtcttatggc tgctactgcg gccaagaggg cagaggagag      960

cctagggacg acctggatcg atgctgtctt tcacaccatt gctgtcttga acaggtgagg     1020

cgactgggct gtctcctgga aaggctccct tggtcaccgg tcgtctgtgt cgatcatact     1080

cccaagtgcg gaggacaaag tctgtgcgaa aagctgctgt gcgcatgcga ccagacagcc     1140

gctgaatgca tgacctccgc ttcttttaat cagagcttga agagtccctc cagactgggc     1200

tgtcctggtc aacccgcggc ttgtgaggac agcctgcacc ctgtgccagc agcacctact     1260

ctggggagca gcagtgagga ggattcagag gaggaccccc ctcaggagga tctgggtcgc     1320

gccaagcgct tcttgcgcaa gagtttaggg ccgctgggga tcgggccact gcatggccga     1380


<210>  4710
<211>  792
<212>  DNA
<213>  Homo Sapiens

<400>  4710
gctccactca tccctcagcg tcttatgtct gcttctaata gcaatgagtt gctcctgaac       60

ctgaataacg gacagctgct tcctctgcag ctccagggcc cactgaactc ttggattcct      120

ccattcagcg gtatcctcca gcaacagcag caggctcaga tcccaggcct gagccagttt      180

tccctcagtg cgctcgacca gttcgccggc ctgttgccca accaaatacc actgacagga      240

gaagcatcct ttgcgcaagg cgcccaggcc ggccaggttg atcccctgca gcttcagact      300

cctcctcaga cccagccagg tccttcccat gtcatgccat atgtgttttc tttcaaaatg      360

ccccaggagc aggggcagat gttccagtac taccccgtct acatggtcct cccttgggag      420

cagcctcagc aaacagtgcc ccgaagtccc cagcagaccc gccagcagca gtatgaggag      480

cagatcccgt tttacgccca gttcgggtac atcccccagc ttgcagaacc cgcaatatca      540

ggaggccaac agcagctggc cttcgatcct cagctgggaa cagcccctga gatcgccgtc      600

atgtccaccg gggaagaaat accgtattta cagaaggaag ctattaactt ccgccatgac      660

agcgcaggtg tgttcatgcc aagcaccagt cctaagcctt caacaacgaa cgtcttcacg      720

agcgcagtcg accagaccat tacccccgaa ttgcctgagg aaaaggataa gactgacagc      780

ctgagagaac cg                                                          792


<210>  4711
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  4711
caggaagagg tttttacccc tccgggagac tcccagaata acgccgacgc gacagattgc       60

cagatcttca cactcacacc acctcccgca cctcggagtc ccgtgactag ggcccagcct      120

attaccaaaa caccaagatg cccatttcat tttttcccaa ggcggccgcg catccacttt      180

cggttcccta atcggccatt tgtgccttcc cggtgcaatc accggttccc tttccagcca      240

ttttactggc cccacagata cttaacatat agatactttc cacggcgcag acttcaacga      300

ggctcctcat ctgaggagtc c                                                321


<210>  4712
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4712
atccaagtac actgtacaca gttttggttc ttcgcacgaa ttaagccaac aatcttttat       60

aacctgtacg ttaaccctga tgaggttttt ctcggtgatg gctgtcatgt aacacacgtt      120

ctgccaaacg tatattacga atttttttac cacccacacg attgcggcat tgttacacag      180

cctttacagg aagtgctgct tctcaaaaca aagattcgct acatcagtcg agattccaca      240

gtcaggtcag agatgccact gagctgcgtg gtacacaaac agaagtgcca g               291


<210>  4713
<211>  423
<212>  DNA
<213>  Homo Sapiens

<400>  4713
gagaatctgc acgtgaagat ttcctgttca ctcgattggc tgatggtttc cgtgataccc       60

gtggcggaaa gccgaaacct ctacatcttc gcagacgagc tgcatcttgg catgggatgt      120

cctgcgaacc ggattcacac atacgtctac gaatttatat atttggtcag agattgtgga      180

attaggacaa gggttgtgtc agaagagact ttgttgttcc aaacagaact gtactttact      240

ccccggaaca ttgaccatga cccgcaggaa atccaccttg aatgcagcac aagcaggaag      300

agtgtgtggc tcacccccgt gtcaacagaa aatgaaatca aattggaccc gtctcccttc      360

atcgcagact tccagacaac tgcagaggaa ctcggactgc tctcatcaag tccaaatctc      420

ctt                                                                    423


<210>  4714
<211>  1362
<212>  DNA
<213>  Homo Sapiens

<400>  4714
aagacaacac cccacacaaa gttcactaaa aagtccgagg agcgcgaaat gcctaaagga       60

ctgaaacctt cctctggccc tcctccagag gaggaagaga ccctgttcac agagatggct      120

gaaatggccg agcctatcac gaagccctct gccctcgaca gcgtcttcgg cacggccact      180

ctcagcccct ttgaaaattt tactctggac cccgcagact ttttcctgaa ctgctgtgac      240

tgctgttccc ccgtgcctgg tcaaaagggt gagcccgggg aaactggcca gcctggtccc      300

aaaggggaag ccggtaatct gggaatccca ggtccgcccg gtgtggtcgg gcctcaaggg      360

ccccgagggt acaagggaga gaagggactg aaaggggaga ggggtgacca gggcgtgccc      420

ggttacccag gtaaacccgg agcgcaagga gaaccagggc caaagggtga taaaggcaat      480

attggcctgg gtggagtcaa gggccaaaaa ggctccaaag gcgatacctg cggaaattgt      540

acaaaaggag agaaggggga ccagggcgcc atggggtccc ccggtcttca tggtggtcca      600

ggagctaagg gggagaaagg tgaaatgggg gagaagggcg agatgggaga caaggggtgt      660

tgtggagatt ctggagagag gggcggaaag gggcagaaag gagaaggcgg tatgaagggt      720

gagaaaggta gcaagggcga ttcaggtatg gaggggaagt ccggaagaaa tggcctgcct      780

ggagccaaag gtgaccccgg aattaaagga gaaaaagggg agctgggacc acccgggtta      840

ttgggcccca ccggtccgaa gggtgacatt ggtaataagg gggtgcgcgg tcctacgggg      900

aagaagggat cccgcggctt taaagggtct aaaggggaac tggccagggt gcctaggtcc      960

gctttcagcg ctggtttgag taagcccttt cctcccccta acatcccaat taaatttgaa     1020

aagatcttat acaacgatca aggaaattac tccccagtga cgggcaagtt taattgcagc     1080

atacccggaa catacgtttt ctcataccac attacagtcc gtggtagacc cgcaagaatc     1140

tcactggtcg cccagaacaa gaaacagttt aagtcccgcg agaccctgta tggccaagaa     1200

atcgatcagg cctccctcct tgtgatactg aaactgtccg cgggagacca ggtgtggctc     1260

gaagtgtcaa aagactggaa tggcgtgtac gtgagtgccg aggacgattc catctttact     1320

ggtttcctgc tctatcctga ggaaactagt gggatctctc ca                        1362


<210>  4715
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  4715
aagcccgtgc aggaggaagg cgatccttac gccgagctcc cagccatgcc ctactggcct       60

ttcagcacaa gcgacttctg gaattacgtg cagcatttcc aggctttagg agcctaccct      120

cagatcgaag atatggctcg gactttcttt gcgcactttc cattgggaag caccttgggg      180

tttcatgttc cgtatcagga agac                                             204


<210>  4716
<211>  1539
<212>  DNA
<213>  Homo Sapiens

<400>  4716
attctcggtg gctcccaggt tgaaaagggc tcttatcctt ggcaggtaag cttgaaacag       60

aggcagaaac atatctgtgg cgggagcata gtgagccccc agtgggtgat tactgcagca      120

cactgcatcg ctaatcgcaa catcgtatcc accctgaatg ttaccgccgg ggaatacgat      180

ctctcccaaa ccgaccctgg agagcagaca ctgactatcg agacggtgat tattcatcct      240

catttttcca ctaaaaagcc aatggactac gacatcgcgc tgttgaagat ggccggcgct      300

ttccagtttg ggcactttgt ggggccgatc tgcttgccgg agttaagaga acagttcgag      360

gctggattca tctgtactac tgctgggtgg ggccgcttaa ccgagggtgg ggttctgagc      420

caggtacttc aggaagtaaa tcttcctatc ctgacttggg aggagtgcgt cgccgcattg      480

ctgactctga aacggcccat cagcggtaaa acattcttat gcaccggttt tcctgacggc      540

ggcagggacg cgtgtcaagg cgacagtggg gggtctctca tgtgtcgcaa caagaagggc      600

gcatggaccc ttgcaggggt gacgagttgg ggactgggtt gcggtagagg ttggcgcaac      660

aacgttagaa aatcagatca gggctccccc ggcatattta ctgatatcag caaggtgctc      720

ccttggattc atgaacatat acaaactggg aacagaagaa agtcaagccg ggcttggtgc      780

tctgagcaag atgttatcgt cagcggcgcc gaaggaaaac tgcactttcc cgagagtttg      840

catctttatt acgagagcaa gcagcggtgc gtgtggacct tattagtccc agaggagatg      900

catgtcctgc tgagtttctc ccacttggac gtggagtctt gccatcacag ctacctttct      960

atgtattccc tggaagacag gccaatcggc aaattctgtg gcgagtctct tccatcttct     1020

atcttaatcg gtagcaatag tttgagactc aagttcgtgt ctgatgctac cgataatgcc     1080

gccagattta acttgactta caaagccctc aaacccaact atattcctga cagcgggtgc     1140

tcctatctca ccgttctgtt cgaggaaggg cttattcaga gcctcaacta tcccgaaaat     1200

tattcagaca aggcgaactg cgactggatc ttccaggctt caaagcacca cctcatcaag     1260

ctgagcttcc aatccctcga gattgaggaa tctggggatt gcactagcga ctacgtgaca     1320

gtccacagcg acgtggagcg gaaaaaagag atagccagac tgtgtgggta cgatgtgccc     1380

actcctgtcc tgagcccatc atccatcatg cttatctcat ttcacagtga tgaaaacggg     1440

acttgccgag gctttcaggc taccgtgtct tttatcccca aggcgggtaa aaaaatcgaa     1500

ttaccaaccc tgtggtttcc tgttctgatt ctggtcatg                            1539


<210>  4717
<211>  822
<212>  DNA
<213>  Homo Sapiens

<400>  4717
cagaaatctt accaggagag cgaaacagga ccagagtcta gtatcattac gaaagttaag       60

gggataacaa ctagtgaaca caaggtgtgg gacgtagagg aatatgtgaa gccaccagaa      120

gggggttccg tattctccat cataacacgc gttgaggcca cccattccca aacacaagga      180

acttgtcctg aaagcattag ggttcacaac gcaacctgtc tgtccgatgc cgactgcgtg      240

gctggggagc tcgatatgct cggaaatggt ctgcgtaccg ggaggtgcgt tccttactac      300

caaggaccat ctaagacttg tgaggtgttt ggctggtgcc ctgtagagga cggcgctagt      360

gttagccagt ttctggggac aatggctcct aacttcacta ttcttataaa aaacagtata      420

cactacccta agttccattt ttctaaaggg aacatcgccg accggacaga cggatacctg      480

aaaagatgca ccttccacga agcaagcgac ctctactgcc caatatttaa gctcggcttc      540

atcgtggaaa aggctgggga atcttttacc gagctcgctc ataagggggg cgtcatcggc      600

gtcattatca attgggactg cgatttagac ttacccgcca gcgaatgtaa cccaaagtac      660

agctttcgcc gcctggaccc aaagcatgtg ccggcctcat ctgggtataa ttttaggttc      720

gctaagtact ataagattaa tggtactacg acccggacct tgatcaaggc ctacggaatt      780

cgcatagacg tgatcgtgca tggccaggct gggaagtttt cc                         822


<210>  4718
<211>  1416
<212>  DNA
<213>  Homo Sapiens

<400>  4718
gacgcacctc ctgggaagat cgccgttgtg ggcgcaggta ttggaggcag cgccgtcgca       60

cattttctgc agcagcactt cggcccgcga gtgcagattg atgtgtacga aaaaggtaca      120

gtcggcggtc ggctggccac catttcagtc aataaacagc actatgaatc tggagcagca      180

tcttttcaca gcctctcctt gcacatgcag gatttcgtca agcttcttgg cctcaggcat      240

cgacgagaag tcgtcggacg cagcgcaatc tttggcggcg aacattttat gttggaagag      300

acagattggt acttgctcaa tctttttcgc ctctggtggc actatggtat ctctttttta      360

aggctgcaaa tgtgggtgga agaggtaatg gagaagttta tgagaatcta caaataccaa      420

gctcacgggt acgccttctc aggagttgaa gaactcctgt actcccttgg agaatcaact      480

tttgtgaaca tgacccagca ctccgtcgcg gagtcactcc tgcaggtagg cgtgacacag      540

agatttatag atgatgtggt gtccgctgtg ctgagagcca gctacgggca gtctgctgcc      600

atgcctgcat tcgccggggc catgtctctg gcgggggccc agggatcttt gtggtcagtg      660

gaggggggaa acaaactggt gtgctcagga ttactcaaat tgacaaaagc gaacgtgatc      720

catgctactg tgaccagcgt cactcttcat agcactgaag ggaaggcctt gtaccaagtg      780

gcgtatgaga acgaggtcgg aaattcctct gacttctacg acatcgtagt gattgccaca      840

ccgctgcacc tcgataattc ttcttccaac ctgacattcg caggcttcca tcctccaata      900

gatgatgtcc aaggaagttt tcagcccact gtcgtatctc tggtgcacgg atacctgaat      960

tcatcctact tcggattccc ggaccctaaa ttgttcccct ttgccaacat tctcactact     1020

gattttccat cctttttctg caccttagac aacatttgtc ccgtgaatat ttccgcgagc     1080

ttcagaagga aacagccgca ggaggcagca gtctggagag tccagtctcc caagccgctg     1140

ttccggactc agctgaaaac acttttccgg agctattact cagttcagac ggctgagtgg     1200

caggcacacc ccctgtacgg aagccgtccc accctcccca ggtttgcact ccatgatcag     1260

cttttctatt tgaacgccct ggagtgggcc gctagcagcg tcgaagtgat ggcggttgcc     1320

gctaagaatg ttgctctgtt agcctataac cgatggtatc aggatttaga taaaatagac     1380

cagaaggacc tcatgcataa agtcaaaacc gagctc                               1416


<210>  4719
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  4719
ctgtattcca gttcagacga cgtgatcgag ctgacaccta gtaactttaa tcgagaagtg       60

attcagtctg attccctttg gctggtcgag ttctacgccc catggtgcgg ccattgccag      120

cgtctgacgc ctgaatggaa gaaagctgcg actgcactga aggacgtggt taaagtgggg      180

gcggtagacg ctgacaagca tcatagcctg gggggccagt atggagtcca gggcttcccc      240

acaatcaaaa tctttggatc caataaaaac cgcccagagg attatcaagg cggcaggacc      300

ggagaggcca tcgtagacgc cgccctttca gcactgaggc agctggtgaa ggaccgcctg      360

ggcggaagaa gcggggggta ctcttccggt aaacaaggac gatcagacag cagctctaaa      420

aaggatgtga ttgagttgac tgacgactct tttgacaaga atgtccttga ctcagaggat      480

gtgtggatgg tggagttcta cgctccctgg tgcggacact gcaaaaattt ggaacccgaa      540

tgggccgcag cagcttctga agtaaaggag caaaccaagg gaaaggtaaa gctggcagct      600

gtggacgcta cagttaacca ggtattagct agccggtacg gcattagagg cttccctacc      660

atcaagattt ttcagaaggg agagtccccc gttgactacg atggtggtcg gacaaggtct      720

gatatcgtca gccgggccct cgatttattc agtgacaacg cccctccacc tgaactgctt      780

gagattatca atgaggacat tgctaaacga acctgtgaag aacatcagtt atgtgtggtg      840

gcagtgttgc cccacatcct cgataccggg gcagcaggta gaaattcata tcttgaggtc      900

ctgttaaaac tggccgataa atacaagaaa aaaatgtggg ggtggctgtg gaccgaggca      960

ggcgcccagt ccgaactcga gaccgctctg gggataggag ggtttggcta cccggccatg     1020

gctgcgatta atgcccgcaa gatgaaattc gcccttctga aggggtcttt cagcgagcag     1080

ggtatcaacg agtttctgcg ggagttaagt tttgggcgag ggtctactgc tcccgttgga     1140

gggggggcgt ttccaacaat cgttgaacgg gaaccctggg acggacgaga tggagaactg     1200

cctgtggagg atgatatcga tttgtctgat gtggaactgg acgacctggg taaggacgaa     1260

ctg                                                                   1263


<210>  4720
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  4720
gacgaggacg aaaacagtcc ttgtgctcac gaagctttgc tggatgagga tacactcttt       60

tgccagggcc tcgaggtgtt ctacccggaa ttgggcaata ttggctgtaa ggtggtcccg      120

gattgcaata actacaggca gaaaatcaca agctggatgg agccaatcgt taaatttccc      180

ggggccgtgg acggggctac ctacatcctc gtcatggtgg accccgacgc accttcacgc      240

gccgagccac ggcaaagatt ttggcgccac tggctggtga ccgatatcaa aggcgcggac      300

ttgaagaagg gaaaaattca gggacaggag ttatctgcct atcaggcccc gagtcccccc      360

gcgcatagtg gttttcacag ataccaattc ttcgtctatt tgcaagaggg caaggtcatc      420

agtctcctgc caaaggagaa caagacacga ggtagttgga agatggaccg gttcctgaac      480

cgttttcatc tgggcgagcc agaggcgtcc actcagttta tgacccagaa ctaccaggac      540

tcacccactc tgcaggcccc acgggagcgc gcatccgagc caaagcataa gaaccaagcc      600

gaaatcgccg cttgt                                                       615


<210>  4721
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  4721
gttgacgaac agccactcga gaactatctg gatatggaat atttcggcac gattggaatc       60

ggcacaccgg cacaggattt cacagttgtg ttcgatacgg gctccagcaa cctttgggtc      120

cctagtgtgt actgctctag cctggcatgc acaaaccaca accggttcaa cccagaggat      180

tcaagcacgt accagtctac ttcagagaca gtatcaatca cctatggcac gggtagcatg      240

actggtattc tggggtatga cacagttcag gtggggggca tttcagacac gaatcagata      300

ttcgggctct ctgagaccga acctggaagt ttcctgtatt acgccccgtt tgatggcatc      360

cttggcctgg cctacccgtc tatcagctca agcggcgcta caccagtttt cgacaacatt      420

tggaatcagg ggctcgtgtc acaggatctt ttctctgtgt atctttcagc cgatgaccaa      480

tctggatccg tggtcatctt cggggggata gacagttcct actacacagg gagtctcaac      540

tgggttcctg tcaccgtgga gggatactgg cagataaccg tggactctat tactatgaat      600

ggcgaggcta ttgcatgtgc cgaggggtgc caggctatag tggatactgg tacaagcttg      660

ttgacgggac ctacaagtcc cattgcaaac attcaaagtg acataggggc cagtgagaat      720

tctgatgggg acatggttgt gtcctgttca gccataagca gcctgcctga catcgttttc      780

acgattaacg gcgtccagta tcccgtgccc ccttccgcct acatcctgca gtcagagggt      840

tcatgcatct ctgggtttca ggggatgaac ctgcccactg aatccgggga gctctggatc      900

ctcggcgatg tgtttataag acagtatttt accgtcttcg accgcgccaa caatcaggta      960

gggctggccc cggtggct                                                    978


<210>  4722
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  4722
agcgtaacat acgaacctat ggcatatatg gatgcagctt atttcggaga gataagtatt       60

ggcacccctc ctcaaaactt cctcgttctg ttcgatactg gttctagtaa tctgtgggtg      120

ccgtctgttt attgtcagtc acaggcgtgt acaagccact cccgtttcaa cccatctgag      180

tctagcacat actctactaa tggtcagact tttagcctgc agtacggctc cgggtctttg      240

accgggttct tcggatatga taccctcacc gttcagagca ttcaggttcc gaatcaggag      300

tttgggttaa gcgaaaacga acccggaaca aatttcgtgt atgcacaatt cgacggtatc      360

atgggtctgg cgtatccagc cctttcagta gatgaagcaa ccacggcgat gcagggtatg      420

gtccaagaag gcgctctgac atcacccgtg ttttccgtct atctttcaaa ccagcagggc      480

tcttccggtg gtgccgtggt attcggagga gtagacagct ccttatatac aggccagata      540

tattgggcac cagtgaccca agagctctat tggcagattg ggatcgaaga attcctgatt      600

gggggtcagg caagcggctg gtgtagcgaa ggttgtcagg ccatcgtcga caccggaaca      660

tccctgctga ccgttccaca gcagtacatg agcgctttac tgcaagcaac tggcgcgcag      720

gaggacgagt acggacagtt tctggtgaat tgtaattcca tccagaactt acctagtctg      780

acgttcataa tcaacggagt ggagtttcct ctgcctccca gttcttatat tttatccaat      840

aatggatact gcaccgtggg tgtcgagccg acctaccttt cttctcagaa cggtcagcct      900

ctgtggattc ttggggacgt cttcctccga agctactaca gtgtgtatga tttgggtaac      960

aacagagtgg gctttgccac tgctgcc                                          987


<210>  4723
<211>  1665
<212>  DNA
<213>  Homo Sapiens

<400>  4723
tcactccccc tgctcatgga cagcgtgatt caggcgctgg ccgaattgga gcagaaagtg       60

ccagccgcaa agacgagaca caccgccagc gcctggttga tgagtgctcc aaacagtggt      120

ccacacaatc ggctctatca tttcctgctc ggtgcatggt cattaaacgc taccgagctg      180

gacccttgcc ctctgagccc agagctgctg gggctgacca aggaagtggc acgccatgat      240

gtccgggagg ggaaggagta tggagtggtg ctggcaccag acggtagtac cgtggccgtg      300

gagccccttc tggccggctt agaggccggc ctgcagggcc ggcgtgtgat caatctgcca      360

ctggatagta tggcggctcc atgggagact ggagatacct ttcctgacgt ggtggcaatt      420

gctccggacg ttagggctac gtcaagcccg ggacttagag atggcagccc agatgtaaca      480

actgctgaca tcggggcaaa tacacccgat gctacgaaag gctgtccgga cgtacaggcc      540

tctctccccg acgccaaggc taagtcccca cctaccatgg tcgactcctt gctggctgta      600

acactggccg ggaacctggg cctgaccttc ctgagggggt ctcagactca gtcacacccc      660

gacctgggaa ctgaggggtg ttgggaccaa ttgtcagctc ctagaacatt tactcttctt      720

gacccaaagg cctctctcct caccatggcc ttccttaacg gagcacttga tggggtaata      780

ctgggcgatt acctgtcacg gacaccggag ccccgcccta gcctgagtca cttgctgtcc      840

caatattacg gagctggcgt cgctcgagat cccggctttc ggagcaattt ccgcaggcag      900

aacggcgccg cactcaccag tgcttctatc cttgcccagc aggtatgggg gacactggtg      960

ctccttcagc ggttagaacc agtccatctc cagctccaat gcatgtctca ggagcaactg     1020

gctcaggtgg ccgcaaatgc aactaaggaa tttacagaag catttctcgg atgcccggcc     1080

atccatccaa ggtgtaggtg gggagcagca ccctatagag ggcgacccaa gcttctgcag     1140

ctgccgctcg gttttctgta tgtgcatcac acttacgtcc cagccccgcc atgtactgat     1200

ttcactcgtt gtgcagccaa tatgcggtca atgcagcgtt atcatcagga cactcaagga     1260

tggggcgaca tcggttacag ctttgtggtg ggcagcgacg gatacgttta tgaaggacga     1320

gggtggcact gggtgggcgc ccataccctt ggacataact cccgcgggtt tggagtggca     1380

attgtgggaa actatactgc tgccctgccg accgaggcag cactgcgtac tgttagagac     1440

acattaccat cttgtgccgt gagggcgggc ctgttgaggc cagattatgc attgctgggg     1500

cataggcagc tggtgagaac agattgccca ggggatgcac tgttcgatct tctgagaaca     1560

tggccccatt ttacagccac ggtcaaaccg cggcccgcga gaagcgtaag caagaggtca     1620

aggcgggaac cccctcccag aacccttccc gcaacggacc tgcag                     1665


<210>  4724
<211>  1068
<212>  DNA
<213>  Homo Sapiens

<400>  4724
gactcatctt ggaacaagac acaggcaaag caggtgagtg agggccttca gtaccttttt       60

gaaaacatct cccagcttac cgaaaagggg ttgccaaccg acgtttcaac caccgtgagt      120

agaaaggcct ggggagctga agctgtagga tgcagcattc agctgaccac gccagtaaat      180

gttctggtca ttcatcatgt gcctgggctt gaatgccacg accaaaccgt ttgttcccaa      240

cgattgcgag aactgcaagc ccaccacgtt cacaataata gtgggtgcga tgtcgcatac      300

aacttcctcg tgggcgacga cggtcgcgtg tacgaggggg tgggatggaa tattcaggga      360

gtgcacactc agggctacaa taacattagc ttgggcttcg catttttcgg cacaaaaaaa      420

gggcacagtc ctagtcccgc agccttatca gccatggaaa atctcattac atatgccgta      480

caaaagggcc acctttccag ttcctacgtc cagcctcttc tgggcaaggg agagaactgt      540

ttagccccca ggcagaaaac ttctttgaaa aaggcctgcc caggggtcgt gccgcgctcc      600

gtctggggag cccgggagac ccattgcccc cgcatgacac tgccagcaaa gtacgggatt      660

atcatccata ccgccggcag gacttgcaat atttctgacg aatgccggtt gctggtgcgc      720

gacatccagt ccttctacat cgaccgactg aagtcatgtg acattgggta taatttcttg      780

gttggacagg atggggctat ctacgagggg gtgggttgga acgtccaggg ctcaagtaca      840

ccaggatacg acgatattgc acttggcatc acgtttatgg gcacttttac aggcattcct      900

cccaacgcag ctgctctgga agcagctcaa gacttgatac agtgcgcaat ggtgaaaggt      960

tatctgaccc ctaactacct gctcgtgggg cactctgacg tggcccggac acttagtcca     1020

ggccaggcac tgtataatat tatctctaca tggcctcatt tcaaacac                  1068


<210>  4725
<211>  1308
<212>  DNA
<213>  Homo Sapiens

<400>  4725
ttgactgatg aggagaaaag gctgatggtc gagcttcata acctttaccg tgcccaggtt       60

agcccgactg catccgacat gttacatatg agatgggacg aggagctggc agctttcgca      120

aaggcatatg cacgccagtg cgtctggggt cataacaaag agagaggacg ccggggggag      180

aacctcttcg ctatcaccga tgagggcatg gacgtgcccc tggccatgga ggagtggcat      240

cacgagcgag agcattataa cctgtctgcc gctacatgca gcccaggtca gatgtgtgga      300

cactacacgc aggtcgtgtg ggccaagaca gagcgtatcg gctgtggatc acacttttgc      360

gaaaagctcc aaggcgtgga ggaaacaaac attgaattgc ttgtgtgtaa ttatgagcct      420

cctgggaatg tgaagggcaa gcggccttac caggaaggca ctccatgtag tcagtgtccc      480

tccgggtacc attgcaagaa cagtctttgt gagccaattg gctcacctga agatgctcag      540

gacctcccat acctggttac agaagctcct agcttcagag ctaccgaagc ttctgacagt      600

cgaaagatgg ggaccccctc tagtcttgcc acaggcattc ccgccttcct ggtgaccgaa      660

gtgtctggca gtctggccac caaggctctg cccgctgttg agacccaagc tcctacctct      720

ctcgctacga aagacccacc ctcaatggcc accgaggccc caccctgtgt taccacggaa      780

gttcccagca tcctggccgc tcatagcctt ccttctctgg atgaggagcc agtgactttt      840

ccaaagagta cgcatgtgcc gattccaaaa tccgctgata aagtaacgga caagacaaaa      900

gtgccaagcc gatcccctga aaactccttg gatcctaaaa tgagcctcac cggagcacgg      960

gagctgctgc cacacgcgca ggaagaggcc gaggccgaag cagaattgcc tccatcttcc     1020

gaagtgctcg cttccgtctt ccctgcccag gataagcctg gcgaactgca ggcgacttta     1080

gatcacaccg gacacacaag ttccaagtca ctccctaatt ttccgaacac ttctgcaact     1140

gctaacgcga caggaggacg cgcattagcg ctgcaatctt cacttcccgg agctgaaggc     1200

ccggacaagc ccagcgtcgt tagtggatta aattctgggc ctggccacgt gtggggacca     1260

cttcttggcc tgctgttact gcccccttta gtgctggccg gtattttc                  1308


<210>  4726
<211>  1137
<212>  DNA
<213>  Homo Sapiens

<400>  4726
gcgggaaggc accctcccgt cgttctggta cccggggacc tgggcaacca gctggaagcc       60

aagctggaca agcccactgt tgtgcattat ttgtgcagta agaagacaga gtcttacttc      120

acaatctggc ttaatctcga gttactcttg cccgttatca tagactgctg gattgacaat      180

atccggttgg tatataataa gacctcaaga gcaacgcagt ttcctgatgg tgtggatgta      240

cgtgtgcccg gatttgggaa gacgttttca ctcgagttct tggacccctc caagagtagc      300

gtcggttcct atttccacac catggtggag tctcttgtcg gctggggtta cactcggggc      360

gaggatgtgc gtggcgctcc ctatgattgg cgtcgggctc ccaacgaaaa tggtccatat      420

tttctggccc tgcgggaaat gatcgaggaa atgtatcaac tctacggcgg ccctgtggtc      480

ctcgtggctc actccatggg taatatgtat acattgtact ttcttcagag acagccacag      540

gcttggaagg ataaatacat ccgcgcattc gtttcattag gcgctccatg ggggggagtc      600

gctaaaaccc tgcgcgtgct tgcctccggt gacaacaacc ggatacccgt gattggacca      660

ctgaaaattc gggaacagca gcgcagcgcc gtcagcactt cctggctcct tccatataac      720

tatacctggt ctccagaaaa ggtgttcgtg cagactccta caattaacta taccctcagg      780

gactatagga agttttttca agatatcggt ttcgaagatg ggtggctgat gcggcaggat      840

acagaaggac tcgtagaggc cacgatgcca cctggagtac agctgcattg tctgtacggg      900

accggcgtgc ctacgcctga cagcttctac tatgaatcat tcccagatcg ggatccgaaa      960

atctgctttg gtgacggaga tgggaccgtg aatctgaaaa gcgccctgca gtgccaagcc     1020

tggcagagta ggcaggagca ccaagtgctc ctgcaggaac tgccagggtc tgagcatatt     1080

gagatgctgg ctaacgccac gacactggcc tatctgaaaa gggtgctgtt agggccc        1137


<210>  4727
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  4727
tcattctggc agttccagag acgcgtcaaa catattactg ggcgatcagc atttttctca       60

tattatgggt acggctgtta ttgcggcctt ggcgacaagg gtataccggt ggatgacaca      120

gataggcatt ctccttcaag cccaagtccg tacgaaaaac ttaaagaatt tagctgtcag      180

ccagtgctga actcatatca gtttcacatt gtgaatggcg ccgtcgtctg cggttgtact      240

ttagggccag gggcgtcttg tcattgccga ttgaaggcct gtgagtgcga caaacagtct      300

gtgcattgtt tcaaggagtc cctgccaacc tatgaaaaaa acttcaagca gttttcatct      360

caacctaggt gtgggcggca caagccatgg tgc                                   393


<210>  4728
<211>  1545
<212>  DNA
<213>  Homo Sapiens

<400>  4728
ggcgtgtatt acgcgactgc ttattggatg ccggccgaaa agaccgtcca agtgaagaat       60

gtgatggaca aaaacggcga cgcctatggg ttctataaca actctgtgaa aaccaccggc      120

tggggaatct tggagataag agctggctac ggcagccaga ccctttctaa tgaaattata      180

atgttcgtcg ccgggtttct ggagggttac ttaacggctc cacacatgaa tgaccactac      240

acaaatttgt atccacagct cataactaag ccgagcatta tggacaaggt gcaggatttc      300

atggagaagc aagataaatg gactcgcaaa aacatcaagg agtataagac cgacagcttc      360

tggcggcata caggttatgt catggcccag atagacggac tgtatgttgg agccaagaag      420

agggcaatct tggaaggtac caaacccatg accttattcc agattcagtt tctgaattca      480

gtgggagacc tgcttgacct gatccctagc ctctccccga ctaaaaacgg gagccttaaa      540

gtttttaaga gatgggacat gggacactgc tcagccctca tcaaggttct tcccgggttc      600

gagaacatcc tgtttgccca ttcatcttgg tacacctacg cggcaatgct ccgaatttac      660

aagcactggg acttcaatgt gattgacaaa gacacatcaa gcagtagact gagctttagt      720

tcatacccgg gcttcttgga aagcctcgac gatttttata tcttgtcttc tggactgatc      780

ctgctgcaaa ctacaaattc cgtatttaac aaaactctgc ttaagcaagt tatccccgag      840

actttgctgt cctggcaacg ggtacgagtg gcaaatatga tggctgacag cggcaagcgt      900

tgggcggata tttttagcaa gtacaactct ggtacctaca acaaccagta catggtgtta      960

gatctgaaaa aggtcaaact gaatcatagc ctcgacaagg gcaccctgta tatcgtcgag     1020

cagatcccaa cttatgtgga gtattcagaa cagacagacg tccttcgtaa gggttactgg     1080

ccgtcctaca atgtgccttt ccacgaaaaa atctataact ggagcggcta ccctctgctc     1140

gttcagaagc tcggactcga ctatagttat gaccttgcac caagggccaa gatctttagg     1200

agggatcaag gcaaggttac agatacggcc tctatgaaat acataatgcg gtataacaat     1260

tacaagaaag acccctatag caggggcgac ccatgcaata caatctgctg ccgggaggat     1320

ttgaattccc ctaaccctag ccctggcggt tgctacgaca ccaaggtggc tgatatctat     1380

ctggccagtc agtatactag ctacgccatt tctggcccaa cagtgcaggg cggtctcccg     1440

gtgttccggt gggacagatt taacaagact ctgcaccagg gtatgcctga ggtgtacaac     1500

ttcgacttca taacgatgaa acccattctc aaacttgata taaag                     1545


<210>  4729
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  4729
atcccagcac ccgggggcag gtgggctcgg gacggacagg tacctccggc atcccggtcc       60

agatccgtac tgctggatgt gtcagctgga caactgttga tggtcgatgg cagacacccc      120

gatgctgtgg catgggccaa cctcactaac gccatcagag aaactggctg ggctttctta      180

gagctgggta cttcagggca gtacaacgat tcattacagg catatgccgc cggagtcgtc      240

gaggccgccg tctccgaaga actgatctat atgcattgga tgaacactgt ggtgaattat      300

tgcggccctt ttgaatacga agtgggatat tgcgaacgac ttaaatcctt cctggaggct      360

aacttggaat ggatgcagga ggagatggag tccaatccgg acagtccgta ctggcatcag      420

gtgcgtctca ctctgttaca gcttaaaggc cttgaagatt cctacgaagg tagggtgagc      480

ttcccagcag ggaagttcac tatcaaacct ctcggcttcc ttcttttaca gttgagcggg      540

gatctggagg atttggagct ggcactgaat aagaccaaaa tcaaaccttc tcttgggtcc      600

ggatct                                                                 606


<210>  4730
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  4730
acctttatac ggtactcctc tacgtgcttt acttttgacg aatattatac tattaccctt       60

gatattaagg ccagcagtca tatttatgaa tcaaatgctg tgtatagcgt ttttgtcccc      120

gtgaatgaca gcgtttatgc tgtggtgatg aagaccctcg atgaaaacag tgactctgct      180

ggcctctggc agcgagcgga caagaactgt tacagtaatt ccacgtacta cgtcaaagat      240

cagtatatga ccgtcctcga agcccagtgg caggcccccg agcctgagaa tatcaccgag      300

gtggaaatcc aggcttttac cgtacagatc cgcgctttgc ctattctgtc cactctgaag      360

ctcagggaga agttgtctac tctggccctg gctgctaaaa ttccgcagtc atcagctttt      420

aaacctttct ttatgattac accaaagtca atacgcctgg agggccttgc taaccaagtc      480

ttttca                                                                 486


<210>  4731
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4731
gagccgctgg acgactatgt gaatgcacag ggagcaagtt tattttccgt gactaagaaa       60

caactgggcg ccggcagtag ggaggagtgc gctgcaaaat gcgaagaaga caaggagttc      120

acttgccgcg cttttcagta ccactcaaag gagcagcagt gcgtgatcat ggctgagaat      180

aagaaatcat ctatcattat caggatgaga gatgtggtcc tcttcgagaa g               231


<210>  4732
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4732
gaacccctcg acgattacgt taacacccag ggcccatctc tgtttagcgt cactaagaag       60

cagcttggcg ctgggtccag ggaggaatgc gccgcaaagt gcgaggagga taaggagttt      120

acctgtcggg cctttcagta ccactctaag gagcagcaat gtgtgataat ggccgagaac      180

cgcaaatcat ccataatcat acgcatgcgc gacgccgtgc tgtttgagaa g               231


<210>  4733
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  4733
atgggcccgc ggtccgggga gcaccaacgg gccagccgca ttcccagcca gtttagcaaa       60

gaggaaaggg ttgctatgaa agaggcctta aagggagcca tacagatccc aaccgtgacc      120

ttttctagcg agaaaagcaa caccacagcc cttgcagagt ttgggaagta tatccacaaa      180

gtctttccta cagtggtatc aaccagtttt atccagcacg aggtcgtgga ggagtacagt      240

catctgttca ctatccaggg tagcgaccct tcacttcaac cctacttact catggcacac      300

tttgacgtgg tgccggctcc cgaggaagga tgggaggtac cgcccttctc tggtctcgag      360

cgagacggca ttatttatgg ccgtggcacg cttgacgata agaatagcgt aatggccctg      420

ctccaggcat tggaactcct gctgatccga aagtatattc ctaggagaag cttcttcatc      480

tcccttggcc acgatgaaga gtctagcggg acaggagctc aacgtatttc cgctcttctt      540

cagtcccgcg gtgtccagct ggcctttatt gttgatgaag gggggttcat tctcgatgat      600

ttcatcccca attttaaaaa gcccatcgcc ctgattgctg tgtcagagaa gggaagtatg      660

aacctgatgc tccaggttaa catgacatct ggccatagca gtgccccccc taaagaaacc      720

agcatcggaa tcctggcagc tgccgtgtct cgcctcgagc aaacccccat gcctatcata      780

tttggcagcg gaactgtggt gacagtgctt cagcaactgg caaacgagtt tccatttccc      840

gtcaatatca ttctcagcaa cccctggctc ttcgagcctt taattagccg gttcatggag      900

cgaaacccgc tgacgaacgc catcattcgt accacaactg ctcttactat tttcaaggcg      960

ggcgtgaagt ttaacgtgat tcctcccgtc gcccaagcta cagtgaattt ccgaattcac     1020

cccggccaga ctgtgcagga ggtccttgaa ctgactaaaa atatcgttgc agacaaccgc     1080

gttcaatttc acgtcttgtc cgcattcgat cccctgccag tgagcccaag cgatgataag     1140

gctctgggtt accagctgct gcgccaaacg gtgcagtctg ttttccccga ggttaatatc     1200

acagcccccg tgactagcat tgggaatact gattcaagat tcttcacaaa tttgacaaca     1260

ggcatttacc ggttctaccc aatctacatc cagcctgagg actttaaacg gattcatggt     1320

gttaatgaga aaatcagcgt gcaagcctac gaaacacaag tgaaatttat tttcgaactg     1380

attcagaacg ccgataccga tcaagagccc gtgtctcacc tgcacaagct g              1431


<210>  4734
<211>  1350
<212>  DNA
<213>  Homo Sapiens

<400>  4734
aaagaagtgt gttacgagga cctgggctgc ttttcagaca ccgagccctg gggcgggacg       60

gctatccggc cactgaaaat tttgccttgg tcacccgaga aaataggcac tcgattttta      120

ctgtatacaa acgagaatcc aaataatttc caaatactcc ttctgagcga tccctccaca      180

atagaggcta gtaacttcca gatggatcgg aaaacccgct ttataatcca tggattcata      240

gacaaaggag acgagagctg ggttaccgat atgtgcaaga aactcttcga agtggaagag      300

gtaaattgta tatgtgtgga ctggaagaaa ggatctcagg caacatacac tcaggctgcc      360

aataacgtga gagtggtggg agcccaggtg gcgcagatgc tcgatatact gttaacggaa      420

tactcctacc ctcctagtaa agttcatctc atcggccaca gtttgggcgc tcacgtggct      480

ggagaagctg gctccaagac ccccgggctg tcccgtatta cagggcttga cccagtcgag      540

gcaagtttcg agagcactcc agaggaagtg cgacttgacc catcagacgc tgattttgta      600

gacgtgatcc atacagacgc tgcacccctt attccattcc tcggtttcgg cacaaatcag      660

cagatggggc acctggactt cttcccgaac gggggggaat ctatgccagg atgtaagaag      720

aacgcactca gtcagattgt ggatctggat ggaatctggg caggcacccg tgattttgta      780

gcctgtaatc acctgcgcag ctataaatac tacctggaga gcatattaaa cccggatggg      840

tttgcggctt acccttgcac ctcttataag tctttcgaat ccgataagtg tttcccttgt      900

cccgatcagg ggtgccctca gatgggtcat tatgccgaca aatttgctgg ccgcacttct      960

gaagagcaac agaagttttt tcttaacaca ggagaagcct ctaatttcgc tcgttggcgg     1020

tacggcgtca gcatcacact gtcaggcagg acggcaactg gacagattaa ggttgcctta     1080

tttgggaaca agggtaacac acaccaatac agcatcttcc gcggaattct taaaccaggc     1140

agtacccatt catacgaatt cgacgccaag ttggatgtgg ggacgatcga aaaagtgaag     1200

ttcctctgga acaacaacgt aatcaatccg accctgccta aggtgggggc tacaaagatt     1260

actgttcaga aaggcgagga gaagactgtt tataacttct gcagcgagga cacagttcgt     1320

gaagatacct tgctcacgtt aacgccttgc                                      1350


<210>  4735
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  4735
ttgcacctgg atgccagtat ccacccattc agattaccat tcagctctaa acccttctta       60

ttgattccga tgagtaatac aaccctcccg cacacggcct ggcccctgtc ttttcttcac      120

cagaccgtct caactttgaa ggctgtggcc gtgacccata gcctgtggca cttgcaaata      180

ccagtggatt gtcaggcatg taacagaaag tccaagaaga tttattgc                   228


<210>  4736
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  4736
atgagctcag aaaaatctgg gctgccggat agcgtgcctc ataccagccc tcctccatat       60

aatgctcctc aaccaccagc cgaaccccct gccccaccgc ctcaagcggc acccagctcc      120

caccatcacc accaccacca ttaccatcag tcagggaccg ctacattgcc caggttaggc      180

gccggcggtc tggcttcatc agctgcaact gctcaacgcg gaccttcaag ctctgccacg      240

cttccccggc ctccgcacca tgccccaccc ggtccggcag ctggggctcc cccccctgga      300

tgtgcaactt tgcccaggat gccgcccgat ccctatctgc aagagaccag atttgagggg      360

cctctgcctc ctcctcctcc tgcggccgct gccccccctc caccagcccc tgcacagact      420

gcgcaggcac ccggcttcgt agtgcctacg catgctggca ccgtagggac actgccgctt      480

ggcggttatg tcgctccagg atacccactg cagttgcagc cttgtaccgc ctatgtgccc      540

gtgtatccag tgggcactcc ttacgcaggg gggactccgg gcggaaccgg ggttaccagt      600

accctgcctc ctccccctca agggcccggg ttggccctgc ttgagcccag gcggccaccc      660

catgactac                                                              669


<210>  4737
<211>  1092
<212>  DNA
<213>  Homo Sapiens

<400>  4737
caggtgagtc cctattccgc gccttggaag cccacatggc ccgcataccg cctgccggtg       60

gtgctccctc aatccactct caatctggcc aaaccggact ttggggccga ggctaaatta      120

gaggtcagct cttcctgcgg cccacagtgt cataagggga cacctctgcc cacctatgag      180

gaagccaagc agtatctgtc ctatgagacc ctctatgcaa atggtagcag gaccgaaact      240

caggtcggga tttatattct cagttcttct ggcgacggcg cacagcaccg cgacagcggg      300

agctcaggaa agagccgtcg aaaaaggcag atttatggtt atgattctag gttttccata      360

tttggcaagg attttctgct gaactatccg ttttcaacta gcgtgaagct gtccactggt      420

tgtactggca ctctcgtggc cgaaaaacac gtgctcaccg cagcgcattg catccatgac      480

ggaaagacct atgtgaaggg cactcaaaag ttgagggtag gatttctgaa acctaaattc      540

aaggacggtg gcagaggcgc caacgacagt acgagcgcta tgccagaaca gatgaaattc      600

cagtggattc gagtgaaacg gactcatgtc cctaaaggct ggatcaaggg taacgcaaat      660

gacatcggta tggactacga ttacgcactg ctcgaactga aaaagccaca taaacgaaag      720

ttcatgaaga ttggtgtaag ccccccagcc aagcagcttc ccggaggacg gattcacttc      780

agtgggtacg acaatgacag acccggaaac ctggtgtacc gattctgcga cgtaaaggat      840

gagacttacg atctcctcta tcagcagtgc gacgcccagc ctggcgcctc aggttcagga      900

gtctacgtga gaatgtggaa gcgacagcag cagaaatggg aacgaaagat tatcgggatc      960

ttcagtggtc accaatgggt ggatatgaat ggctctcctc aggattttaa tgtggccgtg     1020

agaatcacac ccctgaaata tgctcagatt tgttattgga tcaaagggaa ctatctggat     1080

tgtcgcgaag ga                                                         1092


<210>  4738
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  4738
atggtgggag ggcaggacac acaggaagga gagtggccct ggcaagtatc tattcagcgc       60

aatggcagcc atttttgcgg cgggagcctc atcgctgaac agtgggttct caccgccgcc      120

cactgctttc ggaatacgag tgaaacgagc ttgtatcaag tcctcctggg ggccagacag      180

ttggtacaac ctggccctca tgctatgtat gccagagtgc gacaggtgga gtcaaatccc      240

ctgtatcagg ggaccgcatc ctcagcagac gttgccttgg tggaactgga agccccagtg      300

ccatttacaa actacatact cccggtgtgc ctgcccgacc cctccgtgat attcgagacg      360

ggtatgaact gctgggttac cggatgggga tctccgagcg aggaagatct gctgccagag      420

ccaagaattt tgcagaaact cgcagtgcct atcattgaca cccctaaatg taacctgctg      480

tatagtaaag acaccgagtt cggatatcag cccaagacca ttaaaaatga catgctttgt      540

gctggatttg aggaaggcaa gaaagatgcc tgcaagggag attctggcgg cccgctggta      600

tgtctggtcg gacagtcatg gctccaggcc ggtgttatca gctgggggga gggctgtgcc      660

cgtcagaatc ggccaggcgt ctatattcgg gttacagcac atcataattg gattcaccgg      720

ataatcccta aactgcagtt ccagcctgct cggctcggcg ggcagaaa                   768


<210>  4739
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  4739
attgttgggg gctatacatg tgaagagaat agcttgccat accaggttag cctgaactcc       60

ggttcccatt tctgcggagg gtccctgatc tctgagcagt gggtggttag tgcggctcac      120

tgttacaaaa cacggattca ggtgcggctc ggtgagcaca acattaaagt gctcgaggga      180

aatgaacaat tcatcaacgc tgctaagatc atcagacatc ctaaatataa tcgtgacacc      240

ctcgataatg atatcatgtt gataaagctc agcagtcccg ctgtgatcaa cgcccgcgta      300

tccacgatta gcctgccgac aacaccccca gccgccggca ctgaatgttt aatctccggg      360

tggggtaata ccttgtcatt cggggccgac taccctgatg agttaaagtg tttagatgca      420

ccggttctga ctcaggctga atgtaaagcc tcttatcccg ggaagatcac aaactccatg      480

ttctgtgtgg ggtttctcga gggggggaaa gatagttgcc agagagacag cggcggacca      540

gtcgtctgca atggccagct gcagggagtc gtgagctggg gccacggatg cgcatggaaa      600

aaccgacctg gggtctacac caaggtctac aactatgtgg actggatcaa ggacacaatt      660

gcagcgaata gt                                                          672


<210>  4740
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  4740
gtcccattcg acgatgacga caaaattgtt ggcggttata cgtgcgagga gaactccgta       60

ccctatcaag tctctctgaa ctccggcagc cacttctgtg gaggtagcct cattagtgaa      120

cagtgggtcg ttagcgccgg acattgctat aaacctcaca ttcaggtgag gctgggagaa      180

cacaacatag aggttctcga agggaacgaa cagtttatta atgccgcgaa gattatcaga      240

catcctaaat ataaccgaat tatcctcaat aatgacatta tgttaattaa actctccacg      300

cctgccgtaa taaatgccca tgtaagcacc atatccttgc caacggcacc cccagcagct      360

ggcacggaat gccttataag cgggtggggc aacacactga gtagtggcgc agattaccca      420

gacgaactgc agtgtttgga cgcacctgtg ctcacacaag caaagtgtaa ggcaagctac      480

ccactgaaaa ttacatccaa tatgttctgc gtcggatttc tggaaggcgg aaaggacagc      540

tgtcagggag attcaggtgg acccgtggtg tgtaatgggc agctccaggg gattgttagt      600

tgggggtacg gctgtgctca gaagagacgg ccaggagtgt acaccaaagt ctataactat      660

gttgactgga tcaaggatac tattgctgct aacagt                                696


<210>  4741
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  4741
gtggccgggg gcgtagaatc agcccggggg cggtggccct ggcaagcatc attgcgcctg       60

agacgacggc atcggtgcgg tggcagtctt ctgagcagac gctgggtgct ttctgccgca      120

cactgctttc agaaacacta ctacccctcc gaatggacag tgcagttagg agaactgacg      180

agcagaccta ctccgtggaa cttacgggcc tatagctcta gatataaagt ccaggacatc      240

atcgtaaacc ctgatgcact tggggtattg aggaacgata ttgctcttct gcggctggca      300

agtagtgtca cttacaacgc ctatattcag cctatttgca ttgaatcaag tacatttaat      360

ttcgtccata ggcccgattg ttgggtgacg ggatggggat taatttctcc ttccgggacc      420

cctctccctc ccccttacaa cctgagggag gcccaggtga ctattctgaa taatacccgt      480

tgtaattatc tgttcgaaca accttccagc cgctctatga tatgggactc aatgttttgt      540

gcaggggccg aagatgggag tgtggacacc tgtaaagggg actcaggcgg tcccctggtg      600

tgtgacaaag acggactgtg gtatcaggtg ggcatcgtgt cttggggtat ggactgtggc      660

cagcccaatc ggcctggtgt gtatacgaac atctctgtct actttcactg gatcagaaga      720

gtcatgtctc attca                                                       735


<210>  4742
<211>  951
<212>  DNA
<213>  Homo Sapiens

<400>  4742
ggtagagttg gggcacaggg cggggtggcc cttctcttcc cttcagcact gccgagcggc       60

cctggaggcc aggaccccgg ggcctcaggc tgggagccgc ctcctgtagg tgctcccggc      120

tcacccgctg ccccacagtc aagaggaaat gccgtgcgtc cagcttctgt cctgttacct      180

agcgcttgcg gccagcgtac ctctagaatt accggtgggt tgcccgcccc agatagaaag      240

tggccttggc aggtcagcct ccagaccagt aacaggcata tttgcggcgg atccctgatt      300

gcgcggcatt gggtgctgac cgcagcccat tgcatctctg gccacctgga atacaccgta      360

aagctcggcg acacaaacgt tcaccacaga tctaaaaccg ccctggttgt acccgtcagg      420

gacgtggtaa ttcatcgcta cttcactagt ccaggcatca tcgagaacga tatcgcactg      480

gccctgttgg atttccctgt caattattcc actcatatac aactcgtgtg tctgccagag      540

caggcattca tggtgcaggc tggcactaat tgctgggtca caggctgggg caaggttaac      600

gaaaccgaga aaatcgtcac cgagccccag gaggccgagc tgagcatcat tcttcacgac      660

aagtgcaacg aggtccttaa ggaaaagatt agaatgcgta gtgagatggt gaagaagggg      720

actatttgcg gatataacga tcagggaaag gacgcttgcc agggcgactc tggcggaccc      780

cttgtgtgtg agcttaacgg cacctgggtc caggttggaa tagtctcttg gggcattggg      840

tgcggccgaa aagggtaccc cggcgtatac actgaggtgt ccttctataa gaagtggatc      900

atcgatcacc tgagacaggc atcttgtctt aattccaaga catcttcttc a               951


<210>  4743
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  4743
ttcctggcct tggctcaact cttaacctcc aagaatttgc ctgatacagt ggatggtcaa       60

ttacccatgg gacctcatag cagggcctct caggtcgctc cagagaccac ctccagtaag      120

gttgataggg gcgtgtcaac cgtctgcggc aaacccaagg tggtcggcaa gatttatggc      180

ggacgtgacg ccgcagccgg tcagtggcca tggcaggcat cccttctgta ctggggttct      240

cacctctgcg gggccgtgct cattgatagc tgctggctcg tttccacaac ccactgcttc      300

ctgaataagt ctcaagcacc gaaaaactat caggtgctgc ttgggaacat tcaactgtat      360

catcagaccc agcacacgca aaaaatgtca gtgcatagaa tcattactca cccagatttc      420

gagaagttgc atccctttgg gagtgacatt gcaatgttgc aactccatct gcctatgaat      480

ttcacatcat acatcgttcc cgtctgctta ccaagcaggg atatgcagct gccttccaac      540

gtgagttgtt ggattactgg ctggggaatg ttaacagaag atcacaagag ggggcctgtc      600

catacagcag tgccctcccg gcttcaggcc gtgtgttgct ctgggtgtcg cggacagcgg      660

gtcgggtccc gtgtcggtcg gttcagaagt atgatcgtcc attccgaagg gcaacttcgg      720

agcttgatgc cgggagactt ccatctgggg gattctggcg gaccactggt ctgctacctg      780

ccaagcgcat gggtgcttgt tggactggcc agttggggcc ttgactgccg tcaccctgcg      840

tatccatcta tttttacccg ggtaacctat tttatcaatt ggatcgacga gataatgcgg      900

ttgacacccc tctctgaccc cgcacttgcc ccgcatactt gtagccctcc gaaacctctg      960

cgagcggctg ggcttcctgg gccatgcgcc gcacttgttc tcccccagac gtggttgttg     1020

ctccctctga ccctgagggc accctggcag acactc                               1056


<210>  4744
<211>  777
<212>  DNA
<213>  Homo Sapiens

<400>  4744
ataaccggag ggatggaggc agaggtgggg gagttcccct ggcaggtgag catacaggcc       60

cggtctgaac ccttctgcgg ggggagcatt ctgaataagt ggtggatcct tacagccgcc      120

cactgcttgt attccgaaga gttgttcccc gaggaactgt ccgtagtgct cgggacgaac      180

gatttgacct ccccctccat ggagattaaa gaggtggcct caattatctt acataaggac      240

ttcaagagag ctaacatgga caatgatatc gcactgctgt tactcgcctc tcccatcaaa      300

ttagacgatc ttaaggtccc catctgcctg ccaacccagc caggccccgc cacgtggaga      360

gagtgctggg tcgctggttg gggacagact aacgctgctg acaagaactc cgtcaagacc      420

gacctcatga aagcacccat ggtcataatg gattgggaag aatgcagcaa gatgttccct      480

aagctgacta agaacatgct ctgcgcaggg tataaaaacg agtcttatga tgcttgtaaa      540

ggtgattcag gcggtccgtt agtatgcacc cccgaacctg gcgaaaaatg gtatcaggtt      600

ggcatcatct cctggggtaa gtcatgtggg gaaaagaaca cccctgggat atatacgtct      660

ttggtgaact acaacttgtg gatcgaaaag gttacacagc ttgaaggaag accgtttaat      720

gccgagaagc gccggacaag cgtgaaacag aaacccatgg gaagtccagt gtcaggg         777


<210>  4745
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  4745
tttaatccag actacacagt gtcttcaact cccccctatc tggtgtattt gaaaagtgat       60

tacttgccat gcgcaggcgt cctgatccac ccactctggg tgatcacggc ggcacattgt      120

aaccttccaa agctcagagt tatattgggg gtgaccatcc ctgccgattc taacgagaaa      180

cacctgcaag tcatcggtta tgagaaaatg atacaccacc cacattttag cgtcacttcc      240

atcgatcacg atattatgct gatcaaatta aagacagaag cggagctgaa cgattatgtt      300

aaactggcca atctgccata ccagacaatc tcagaaaata ccatgtgctc cgtgtccaca      360

tggtcataca acgtgtgtga tatctacaag gaaccagata gccttcaaac tgtcaacatt      420

agtgtgatat ccaagcccca gtgtcgtgat gcctacaaga cgtataacat aacagagaat      480

atgctgtgcg tgggaatcgt ccccggacgg cggcagccat gcaaagaagt cagcgccgct      540

ccagccattt gtaatggtat gcttcagggc atcctgtctt ttgcagatgg gtgtgtgtta      600

agagccgacg tgggcatata tgctaagatt ttttattaca taccctggat cgagaatgtt      660

atccagaaca ac                                                          672


<210>  4746
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  4746
agcctgccat gtgatgtttg ccaagatatt gccgctgccg ccggtaatgg ccttaatccc       60

gacgccacgg aatccgatat cttggccctg gtgatgaaaa catgtgagtg gctcccctca      120

caggagagta gcgccgggtg taaatggatg gtggacgcgc actctagtgc aattctcagc      180

atgctgcggg gagcacccga cagtgctcct gcacaagtgt gtacagctct ttccctgtgc      240

gaacccctgc ag                                                          252


<210>  4747
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  4747
tctgaaggac atcccagcca cccacctgca gaagaccggg aggaagcagg gagccctaca       60

ctgccgcaag gaccacccgt cccgggcgac ccatggccag gagcaccacc tttgttcgaa      120

gatcctcccc caacccgtcc aagtcgaccc tggcgggacc tccctgagac tggcgtgtgg      180

ctccccgagc ctccaaggac tgatccgcct cagcctccga gaccggacga tccttggccc      240

gccggccctc agccacctga gaatccctgg ccccccgccc cagaagttga caaccgtcct      300

caagaggagc cggacctgga cccacccagg gaagaatatc ga                         342


<210>  4748
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  4748
tccgttagcg aaatccagct tatgcataat ctcggcaagc accttaatag catggaacgg       60

gtggaatggt tgcgtaaaaa acttcaggat gtccataact ttgtcgcgtt aggagctccg      120

ctggcaccga gggacgccgg ctctcaacgg ccaaggaaga aggaagataa cgtgcttgtg      180

gagtctcacg aaaaaagcct gggtgaagca gataaggcag acgttaacgt tctcacaaaa      240

gctaagagcc ag                                                          252


<210>  4749
<211>  1359
<212>  DNA
<213>  Homo Sapiens

<400>  4749
caagaagccg ccccagtagg accccgaaag ccctttttcg agcggctgag gcggttggag       60

gaacaattcc gacggtttca ggaagtgacc tggactcacc tgcagaatat tgccagcaat      120

tacaatgtgt cctacaatgt ggacgtgagg tttcgctctc tcgcagagga gtcccaggcc      180

gtggcacagg ccgttaaccg gagccaagcc tccgtgcaag gcgagttggc tcagctgaaa      240

gcgtgggtcc ggaaacttca gaggagaggc aggaaagttg acacgcggtt gcgcgctctt      300

gacctgaccc ttggggaacg ttcacagcag agggctagag aaagaaaagc acacaaggcc      360

cagcgagatg ccctgcagga ctcccttgca agattggaag gactggtcca ctctcagggc      420

gctcgactgg ctgctctgga aggcagactt cccgtagcgc atcccggcac tgcggccttg      480

gggcctgccc tcgttcccac accaactcag cccgaagagc tggggccaac ctccctgaag      540

ctgcagcgcg ataggcagga attgcgagcc gcttcagagc atcgagggcc gccacaggat      600

agtagtgcgc cgttgcaggg gcggcgcgag ccaccagctt ccggctccca ccgggtactc      660

tctggaactg cccctaagga ccccaggcag caggcatggt cccctcaggt cccgggagag      720

atttgcggcg tgggtcccac attggtgttc cctaatgcct ccacacgcaa cgtagtattc      780

ctgagccctg ggtttgtaac agctctccgg gctctgtctt tctgctcttg ggtgaggacc      840

gcgtcagggc gtttgggaac tctgctctca tacgcaacgg aggataacga caataagctg      900

gtgctgcacg ggcgcgatag tctccttcca ggatctatcc actttgttat cggtgacccc      960

gctttcaggg aactgcctct gcaactcctt ctggacgggc agtggcacca catttgtgta     1020

atctggacct ctactcaggg aaggtattgg ctgcatgtgg atagaaggct tgtagccacg     1080

ggctcccgtt ttcgcgaggg ctacgagatc ccacccggag gaagcctggt gctcggtcaa     1140

gagcaagaca gtgtcggtgg gggatttgat agctcagaag ccttcgttgg tagtatgtct     1200

ggattagcga tttgggatcg ggccctggtc cctggtgaag tggcgaattt agccatcgga     1260

aaggaatttc ccacgggcgc aatcctgact ctggccaatg cagccttagc tgggggtttc     1320

gtacaggggg ccaactgtac atgcttggaa agatgcccc                            1359


<210>  4750
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  4750
gggctggccg accctcactc tctttgctac gatatcactg ttattcccaa gtttcgtccc       60

gggcctcgct ggtgcgctgt acagggacag gtagacgaaa agacatttct ccattacgat      120

tgtggttcca agacagtgac tcccgtatca ccccttggaa agaagctgaa tgtgaccaca      180

gcttggaaag cacagaaccc tgtcctgcgc gaagtggtgg acattctgac ggagcaactg      240

ctggatatcc aactggaaaa ttatataccc aaggaaccac tgaccctgca ggctcgtatg      300

agctgtgaac agaaggcaga aggacacggc tctggtagct ggcaactgtc ctttgatggc      360

cagatattcc tcctgttcga tagcgaaaac cgaatgtgga ccacggtaca tcctggcgct      420

cgcaagatga aagagaagtg ggagaacgat aaggacatga caatgtcttt tcactacatc      480

tcaatgggcg actgtaccgg gtggcttgag gattttctca tgggaatgga cagcaccctc      540

gagccaagcg ccggagcccc accaacaatg agttccggg                             579


<210>  4751
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  4751
cgtcgtgacg atccccacag cctgtgctac gacataacgg tcatcccaaa attcaggcct       60

gggccacgtt ggtgcgctgt ccaggggcaa gtggacgaga agacctttct ccactacgat      120

tgtggaaaca agaccgtgac acccgtgtcc ccgctgggaa aaaagctgaa cgtaacaatg      180

gcctggaagg cacaaaatcc tgtgcttcgg gaggtggtgg atatcctgac agaacagctc      240

ctggacatcc aactggagaa ctatacccca aaggagccgc tgaccttgca ggctagaatg      300

agctgtgagc agaaggccga ggggcactcc agcggttctt ggcaattctc catcgatggc      360

cagacctttc tgctgtttga ttccgaaaaa agaatgtgga ctaccgtcca ccctggcgcc      420

cggaagatga aggagaagtg ggagaatgat aaggatgtcg caatgtcctt tcactatatt      480

tccatgggtg attgcattgg ttggctggaa gacttcctga tggggatgga tagcaccctt      540

gagccctctg ctggcgcccc tctggccatg agctccgga                             579


<210>  4752
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  4752
atggccgtgg atgttgagtt cggagtggct ggttggtggg aggccgccgc ccccttaagt       60

cccagtgctg ttgctgccac atttaccgag acctggcctg gctccgagcg agctgagccc      120

gggcgaattc aacacccact ctggcccggg agttcagagg ggctccagct tctggtctgc      180

tttctgctcc ttaatagctg tccaggcggg tgctccgata ccagcgcaca cgacggtcag      240

gatcaagttg gggttgggca gctctggcct ctgcagggat ttgcaacacc agtgtttcag      300

cacctgcaag tagtgctgca gcagataatc cctcagggtt tgttttggaa ggatgacatt      360

acccaagatg caatgattca gaagatggaa cacgcctctc ggctgcaccc acaggagcca      420

tgtctcaaag atgggaaagc cttgttccca acaaaaacta cagagtcccc tctcgccaaa      480

gtgaacaggg atcagtgctt tacgtctgag gtcgtgtcaa aggcactcaa gcaggaagtg      540

gccaaccctg tgaaaattac atacagatgc agttacggcg gcctcgatat gatgcaggca      600

cccggcccca gcaaagagga aattatttat aaaattatga gattgctgtg ggctaccagc      660

tactgcggcc cacaaccatg tggt                                             684


<210>  4753
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  4753
gacaatgcct cccaggaata ctataccgca ctgattaatg ttactgtgca ggagccagga       60

cggggggcac cactcacttt cagaatagac cgcggccgct acgggctcga ttcccctaaa      120

gcagaggtta ggggacaggt gcttgcacct ttgcccctgc atggggttgc tgatcatctg      180

ggctgcgatc ctcagactag gttctttgtg ccgccaaata ttaagcagtg gattgctctg      240

ctccaacgcg gaaattgcac cttcaaagag aaaatctcac gggctgcttt ccataacgca      300

gtggctgtcg ttatttataa taataaaagc aaagaggaac ccgtcaccat gacacaccca      360

ggaactggcg acataattgc cgtgatgatt acagaactcc ggggcaaaga tattctgtct      420

tatcttgaga aaaacatctc agtgcagatg accatcgcag tgggtacccg gatgccacca      480

aaaaattttt cacgcggttc c                                                501


<210>  4754
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  4754
aaggccattt ggacggctca tctcaatatt actttccagg tcggcaatga gataacgagc       60

gagctggggg agtcaggagt ttttggcaac cattcaccac tggaacgggt cagcggcgtg      120

gtggccctgc ctgaagggtg gaatcagaat gcctgccatc cccttactaa cttctcaaga      180

ccaaagcaag cggattcctg gctcgccctc atcgagaggg ggggatgtac gtttacccat      240

aagatcaacg tagcagcgga gaagggggcg aacggggtga tcatttacaa ttaccagggc      300

actggatcca aggtcttccc tatgtcccac caaggcacag agaacatcgt ggcagtcatg      360

atttccaacc tgaagggcat ggaaatactg cactccatcc agaagggagt gtacgtcacc      420

gtcattatag aagtaggtcg gatgcatatg                                       450


<210>  4755
<211>  447
<212>  DNA
<213>  Homo Sapiens

<400>  4755
ctcattcggg ctactagcga ccataatgcc agtatggatt ttgccgatct cccagcgctc       60

ttcggggcta cactgagtca ggaagggttg cagggtttct tagtggaggc tcaccctgat      120

aacgcctgtt cacctatcgc gcccccaccg cctgccccag tcaacggatc agtgtttatt      180

gctctgcttc gaaggttcga ctgcaacttc gaccttaagg ttcttaatgc acagaaggcc      240

ggatacggcg ccgctgttgt ccataatgtc aatagcaacg agcttcttaa catggtgtgg      300

aactcagaag agatccagca gcaaatctgg attccttcag tattcatagg ggaacggtcc      360

tcagagtatc tgcgggcatt gttcgtttat gagaaagggg cccgggttct gctcgtccct      420

gataacacct tccccctggg ctattac                                          447


<210>  4756
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  4756
atgtggctgt tcactgtgaa tcaagtgctg cgtaaaatgc agcgcagaca ctcttccaac       60

actgataata tccctccgga gcggaatagg agccaagctc tgagcagtga agctagcgtt      120

gatgaggggg gcgtctttga aagcctgaaa gccgaagcag cgagccctcc tgctcttttt      180

agcggcctct ccgggagtct gccaaccagc tctttcccct cttctctcgt gttggggtct      240

agtgctggcg ggggcgacgt gttcatacag atgccagcca gccgtgaaga aggtgggggg      300

aggggcgaag gcggtgctta ccaccacaga caaccacatc accactttca tcatggcggg      360

caccgcgggg ggagcctgct gcaacatgtc ggaggggacc accggggaca ctccgaggaa      420

gggggcgatg agcagccagg aacacctgca ccggcgctga gtgagcttaa ggcagttatc      480

tgttggctgc agaagggcct tccttttata ttgatacttc tggccaaact ttgtttccaa      540

cac                                                                    543


<210>  4757
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  4757
caggggaacc gctggaggag gagcaaaaga gcttcttacg ttagtaaccc aatctgcaag       60

ggttgcctga gttgttccaa agacaatgga tgttccagat gccagcagaa gcttttcttc      120

tttcttaggc gcgaaggcat gagacagtac ggagagtgtc tgcactcttg tccctcaggg      180

tattatgggc accgcgcacc agatatgaat cgctgcgcac gctgcagaat tgagaactgc      240

gattcttgtt tttctaaaga cttctgtacc aagtgtaagg tgggttttta cctgcacaga      300

ggacgctgtt ttgacgagtg ccctgacggg ttcgccccct tggaagagac aatggaatgc      360

gtagagggct gcgaagttgg ccattggtct gaatggggaa cctgctcaag aaacaaccgc      420

acttgtggat tcaaatgggg cttagagact cgcactagac agatcgtgaa gaaaccagtc      480

aaagatacca tcctctgtcc taccatcgca gagtcacgca gatgtaagat gacaatgcgt      540

cattgcccag gcgggaagag gacgcctaaa gccaaagaaa aacgaaataa aaagaagaaa      600

cgcaagttga tagaacgcgc acaggaacag cattcagtgt tcctggccac agatcgggca      660

aaccaa                                                                 666


<210>  4758
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  4758
accaaacttg aagagcattt ggagggaatc gtcaatatct tccaccagta tagtgtgagg       60

aagggacact ttgacaccct ctcaaaaggc gaactcaagc aactgctcac caaagaactt      120

gcaaacacaa tcaagaatat caaagataag gccgtgatcg atgagatttt tcagggactc      180

gacgctaatc aggacgagca agtggacttt caggaattca ttagtctggt ggccatcgcg      240

ctcaaggcag ctcattacca tactcataaa gaa                                   273


<210>  4759
<211>  1242
<212>  DNA
<213>  Homo Sapiens

<400>  4759
tcaagaccta gatcttcccc ggacgatctg aaggcgctca cccgtaatgt gaatcgcctc       60

aatgagtcat tcagggactt acagctccgg ctccttcagg ctcccttaca agctgatctt      120

accgaacaag tttggaaagt acaagacgca cttcaaaacc agagcgacag cctcctcgca      180

ctggctggag ctgtgcagcg cctcgagggt gccctctggg gcctgcaggc ccaggcagtg      240

cagaccgaac aggccgttgc actcctcaga gatcggacag gccaacagtc tgacactgcc      300

caactcgaat tataccagtt acaggtggag tctaacagct cccaactcct gctgcggcgg      360

catgcggggc tgcttgatgg ccttgcgcgg agagtaggaa tattaggaga agaattggca      420

gatgttggcg gggtactccg agggcttaac catagtctct cctacgatgt cgcacttcac      480

agaacccggc tccaagatct gagggtgctt gtatccaacg cctcagaaga cactcgacgt      540

cttcgtctgg ctcacgtggg aatggaactg cagctgaagc aagaactggc aatgctcaat      600

gctgtgaccg aggatttaag actcaaagat tgggaacact ctattgcact gcgtaacatc      660

tcactggcca aagggcctcc agggcctaaa ggagaccagg gagatgaggg aaaggaagga      720

aggcctggga tccccgggct ccccggcctg agaggcctcc cgggcgagcg ggggactcct      780

gggctgcccg gtcccaaagg cgacgatggg aagcttggcg ccactggccc tatggggatg      840

agggggttta aaggggacag aggcccaaag ggcgagaagg gcgaaaaagg cgatagagca      900

ggcgatgcct ctggcgtaga ggcgcctatg atgatcagat tggtcaacgg aagtgggcct      960

catgaggggc gtgtggaagt gtatcacgat cgtcgctggg gaaccgtatg cgatgatggc     1020

tgggataaga aggatggaga cgtcgtctgc cggatgctgg gattccgagg cgtcgaagaa     1080

gtgtacagga ctgccaggtt cggccagggg acaggccgga tttggatgga tgacgtagcg     1140

tgcaaaggaa cagaggaaac tattttccgc tgctcattca gcaaatgggg agtcacgaac     1200

tgcggccacg ccgaggacgc ctctgtgaca tgtaatcgcc ac                        1242


<210>  4760
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  4760
gaagacaacg atgagttttt tatggacttt ttgcaaactc tgctggtcgg cacacccgag       60

gagctgtacg agggtacatt gggcaagtac aatgtgaatg aggatgcaaa ggcagccatg      120

acagaactga agtcctgtat cgatgggctc cagccaatgc ataaagccga actggtgaaa      180

ctgttggtgc aggttctcgg ttctcaggac ggggca                                216


<210>  4761
<211>  1161
<212>  DNA
<213>  Homo Sapiens

<400>  4761
atgaaacctg gacccccaca tcgcgccggt gcagcacatg gcgctggcgc aggggccgga       60

gcagccgccg gcccaggagc acgcgggctc ttgctgccgc cgctgctgtt actcctgctc      120

gccggccgag cagctggcgc tcagagatgg aggtccgaaa acttcgaaag accagttgat      180

ctggagggca gtggcgacga cgatagtttt cccgatgatg agttggacga cctgtactcc      240

gggtccggct cagggtactt cgaacaggag agcgggattg aaaccgctat gagattcagc      300

ccagacgttg cattggccgt gtccacaaca ccagcagtgc tccccacaac taacattcag      360

cctgttggca ccccattcga ggagctgcct agtgagcggc ccacactcga acccgccacc      420

tcacctctgg tggtgaccga agtcccagag gaaccctctc aaagggctac taccgtaagc      480

actaccatgg caaccaccgc ggctacctct acgggtgatc caacagtagc cacggtcccg      540

gcaacagttg ctacggccac tcctagcacc ccagccgcac ccccattcac ggccacaacc      600

gccgtgattc gaaccacggg tgtcagaaga ctgctcccgt taccccttac gacggttgct      660

accgctcggg ccacaacccc tgaagcgccc agtcccccaa ccacagcagc ggttctggat      720

actgaggcac caacgcccag actggttagt accgcaacct cccgcccaag ggcactgcct      780

aggccggcca ccacacagga acccgatatt cccgagcgat ccactctgcc attggggacg      840

acagcacccg gacctaccga agtggcccag acccccactc cggagacctt tttgacaacc      900

ataagggacg agcctgaggt gcctgtctcc ggcggaccca gcggcgattt cgagctgcca      960

gaagaggaaa ctactcagcc tgatacagcc aacgaggtag tggcagtcgg tggggccgcc     1020

gccaaggcca gctcaccacc tggaaccctc ccaaagggcg ctcggcctgg gcccgggctc     1080

ttggataacg ccattgatag cggctcaagt gccgctcagc tcccccagaa gagtattctc     1140

gagaggaaag aggtcctggt g                                               1161


<210>  4762
<211>  426
<212>  DNA
<213>  Homo Sapiens

<400>  4762
aaggggctca tggtgatcac tgggtccgaa agcccaatag tgttgctgtc cggctccatg       60

gagcccgcat ttcatagggg ctatctgctg tttctgacca atcgggtaga agatccgatc      120

agggtaggcg aaatagccgt attacggatc gagggaagga agattcctat cgtacaccgt      180

gtactgaaaa ttcatgagaa gcagaacggg cacataaagt tcttaactaa aggggacaat      240

aacgctgtcg atgatcgagg cttgtataag caagaccagc actggctgga gaagaaggat      300

gtggtcggac gggcccgcgg ctttgttccg tatattggaa ttggcacatc tcttatgaat      360

gactatccca aacataaata tgaagttttg tttcttctgg gactgttcgt cctggtccac      420

cgggag                                                                 426


<210>  4763
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  4763
cagaaaggcg gctctaaggg ccggctgcca tctgaattca gccagtttcc tcacggacag       60

aagggccagc attactctgg acagaagggt aaacagcaaa ctgagagcaa gggaagtttc      120

tccattcaat atacctatca cgtggacgca aacgatcacg atcagtcccg gaaaagccag      180

cagtacgacc ttaacgcact gcataagacc acaaagagcc agcgccactt ggggggatcc      240

cagcagctgc tgcataacaa acaggagggg agagatcatg acaagagcaa gggtcacttc      300

catcgcgtgg ttatccatca caagggcggc aaagcccatc ggggaaccca gaacccttct      360

caagatcagg ggaacagccc atctggcaag ggaatctcca gccagtactc aaacaccgaa      420

gaaagactct gggtccacgg tctcagtaag gagcagacct ccgtctccgg tgcgcaaaag      480

ggccgaaaac agggcggtag ccagagcagc tacgttttac agacggagga attagtggca      540

aataagcagc agagggagac gaaaaattca catcagaata aaggacacta tcagaacgtg      600

gtagaggtga gggaggagca ttccagcaag gtccagacgt ccttgtgtcc tgcgcatcag      660

gacaagctcc aacacggcag taaggacatc ttcagcacac aagacgagct gttagtgtat      720

aataagaacc agcaccaaac caagaacttg aaccaagacc aacagcacgg ccgcaaagca      780

aacaagattt cctatcagag cagttctact gaagaaaggc gcttacacta cggggaaaat      840

ggtgtccaga aggacgtctc tcagtcaagc atatacagtc agactgagga gaaagcacag      900

gggaagtccc agaagcaaat tacaattccc tcccaggagc aggagcattc acagaaggca      960

aacaaaatca gttatcaaag ctcaagcaca gaggagaggc gtcttcatta cggcgagaac     1020

ggggtccaaa aagacgtaag tcagcggtcc atatacagcc agaccgaaaa acttgtggcc     1080

ggcaaaagtc agattcaggc tcccaaccca aagcaggagc cttggcacgg tgagaatgcc     1140

aagggcgagt caggccaaag cactaatcgg gagcaggacc tcttaagcca tgaacagaag     1200

ggccggcatc agcacggatc ccacggcggc ttggatattg tcattataga acaagaggac     1260

gattccgacc gtcatctcgc tcagcacctg aacaacgaca gaaacccact gttcaca        1317


<210>  4764
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  4764
cttgtcgatc aggaagcttc agatctgatt cacagcggcc ctcaggattc ttcccctggc       60

cctgccctcc catgccacaa gatcagcgtg agcaacattg attttgcctt caagctgtac      120

agacagttag ccttgaatgc acctggagaa aatattctgt ttttcccagt ctctattagc      180

ctggcattgg caatgctttc ctggggcgcc cccgttgcct ctagaacaca gctgctcgag      240

ggattgggat ttactctcac agtcgtgccg gaggaagaaa ttcaggaggg attttgggat      300

ctgctgatac gccttagagg gcaagggcct cgactgctgc ttacaatgga tcagaggaga      360

ttcagtggtc ttggtgcaag ggcgaatcag agcttagaag aagcgcaaaa gcacattgac      420

gagtacaccg agcaacaaac ccagggcaag ctgggagctt gggagaagga tctgggcagc      480

gaaacgactg ccgtccttgt gaatcatatg ttgctgcggg cggaatggat gaaacctttc      540

gattctcatg cgacctcacc caaggagttt tttgttgacg agcacagcgc agtgtgggtt      600

ccaatgatga aagagaaggc atctcatcgc ttcctccacg accgcgagct ccagtgctct      660

gtacttagaa tggaccacgc cggtaatacc actactttct ttatcttccc gaatagggga      720

aaaatgcgtc acttagagga tgctctgctc ccagagaccc tcatcaagtg ggactccctg      780

ctgcgtacga gggagctgga tttccatttt cccaaattca gcatcagccg aacctgccga      840

ctggaaatgt tgttgccg                                                    858


<210>  4765
<211>  1197
<212>  DNA
<213>  Homo Sapiens

<400>  4765
agtctcgttg aggacccaca gggagacgcc gcgcagaaaa ccgatacatc ccatcatgac       60

cagggcgact gggaggacct cgcttgtcaa aaaattagct acaatgtgac cgatctggcc      120

ttcgacctgt ataagagttg gcttatctac cacaaccagc acgtcctcgt gacacctacc      180

tccgtggcta tggcttttag gatgctgtcc ttgggaacaa aggccgatac caggacagaa      240

attttggagg gactgaacgt caacttgact gaaacacccg aagccaagat tcatgagtgt      300

ttccaacagg tattacaagc cctgtcacgt ccagacacac gcctgcaact cacaaccggt      360

tccagcctct tcgtgaataa gtctatgaaa cttgttgaca cctttctcga agacacaaaa      420

aagctttatc actctgaagc atcctctatt aattttcggg ataccgagga ggcaaaggag      480

cagattaaca attacgtaga aaagcgcact ggtcgaaagg tggtcgacct ggtgaagcac      540

ctgaagaagg acacatctct ggccctggtg gattacatct ctttccacgg caaatggaaa      600

gacaaattta aagcagaacg catcatggtc gagggttttc acgttgatga taagacaatc      660

attcgcgtcc ccatgattaa tcacctgggc cgttttgaca tccacagaga tcgggagctg      720

agcagctggg tgctcgccca acactatgtg ggcaatgcca ctgctttctt cattctgccc      780

gacccaaaga aaatgtggca gctggaggaa aagctgacct actcccacct ggagaacata      840

cagcgcgcat ttgatattcg gagcattaac cttcattttc caaaactgtc tatttctggc      900

acgtacaaac ttaaacgggt tccccgcaac ctgggcataa caaagatctt ctccaacgag      960

gcagatctga gcggcgtttc ccaggaagca cctctgaagc tgagcaaggc cgtccacgtg     1020

gccgtcttaa caatcgatga aaaaggcacc gaagccaccg gggctcctca tctcgaggag     1080

aaagcgtggt ctaaatacca aaccgtgatg tttaatcggc cattcctggt catcatcaaa     1140

gaatacatta ctaatttccc cctgttcatc ggtaaggttg tgaatcccac gcagaaa        1197


<210>  4766
<211>  1125
<212>  DNA
<213>  Homo Sapiens

<400>  4766
atggatgcgt tgcagctggc aaattctgct tttgccgtcg acctgttcaa gcagctctgc       60

gagaaagaac cactgggcaa cgtattattc agcccgatct gcctctctac ctctctgtct      120

ctcgcacagg taggtgctaa gggcgatacc gcaaacgaaa ttggccaggt tctgcatttc      180

gagaacgtca aagacgtgcc attcggtttc cagaccgtca ctagcgatgt gaacaaactc      240

agcagttttt actcactcaa gttgattaag agattgtacg ttgacaaatc cttgaatctg      300

tctacagagt tcatttccag tactaaacgc ccttatgcca aagagcttga gaccgttgac      360

ttcaaggata agcttgagga aaccaaaggc cagatcaaca attcaatcaa agacctgact      420

gatggccatt ttgagaacat tctggctgat aatagtgtga acgaccaaac caagatcctc      480

gtcgtaaacg ccgcctattt cgtgggaaaa tggatgaaga aattctctga aagcgaaact      540

aaggaatgtc ctttccgggt caacaaaaca gacacaaaac cggttcagat gatgaatatg      600

gaagcaacct tttgtatggg aaacatcgat tccatcaact gtaaaatcat cgagctgccc      660

tttcagaaca agcacttgag catgttcatc ttactgccta aagatgtgga ggacgagtcc      720

accgggctgg aaaagatcga gaaacagctg aatagtgagt ctttaagcca atggacgaac      780

ccctctacca tggccaatgc taaggtaaaa ctgagcatcc caaagttcaa ggtggaaaag      840

atgatcgacc ctaaagcgtg cctcgaaaac ttggggctta agcatatttt ttcagaggac      900

acaagcgact tcagtggcat gtctgaaaca aaaggggtgg cattgagtaa tgtaatccac      960

aaagtttgtt tggagatcac agaggacgga ggagattcca tagaagtgcc cggcgcccgc     1020

attctgcagc acaaagatga acttaatgcc gatcatccat tcatatacat catacgtcat     1080

aataaaacga ggaacatcat cttttttggc aagttctgca gcccc                     1125


<210>  4767
<211>  1296
<212>  DNA
<213>  Homo Sapiens

<400>  4767
cacggaagcc cggtggatat ctgcacggcc aagccgcgcg atattccaat gaatcctatg       60

tgtatttatc gtagccccga gaaaaaagcc actgaggatg agggcagcga gcagaagatt      120

ccagaagcga ctaatcgccg ggtctgggag ctgtcaaaag caaactcccg cttcgccacc      180

accttttatc aacatctggc cgacagcaaa aacgataacg ataacatttt tctgtcccca      240

ctttctatct ctactgcttt tgcaatgacc aagctgggag cctgtaacga tacattgcag      300

cagctgatgg aggtctttaa gtttgacaca atcagtgaaa aaacttctga ccagatccac      360

ttctttttcg ctaaattgaa ttgccggttg tacagaaaag ccaacaaatc ctcaaagctc      420

gtgtcagcca atcggctctt cggagacaag tctttaacct ttaacgaaac gtaccaggac      480

atcagcgaac tggtgtacgg agcgaagtta cagccactcg acttcaagga aaatgcagaa      540

caaagtaggg ctgccattaa taagtgggtg agtaacaaaa cagaagggag gattaccgat      600

gtcattcctt ccgaggcaat aaacgagctt accgtgcttg tcttggtaaa caccatttac      660

tttaagggct tgtggaaatc caaattttca ccagagaaca cacggaagga gctgttttac      720

aaggcggatg gcgaaagttg cagcgcatcc atgatgtacc aggaggggaa gttcagatat      780

cgcagggtgg cagaggggac ccaggttctg gagctcccct tcaaaggcga cgacattacc      840

atggtgctga tcttaccgaa acctgaaaag tctcttgcta aagtcgaaaa agagttgacc      900

ccagaggtcc ttcaggaatg gctggacgag ttggaggaga tgatgttggt ggttcacatg      960

ccccggttcc ggattgaaga tggcttctct ctcaaggagc agctgcagga tatggggctg     1020

gtggacctgt ttagtcctga gaagagcaaa ttgccaggca tcgtggccga agggcgggac     1080

gatctctacg tgtctgatgc atttcataag gctttcctgg aggtgaatga agaggggtct     1140

gaggctgctg cttctacagc cgtcgtgatc gctggccgct cacttaaccc caaccgggtg     1200

actttcaaag caaatcgccc ttttttagtg tttatccgtg aggtcccact gaatacaatt     1260

atctttatgg gtagggttgc aaacccctgt gtcaaa                               1296


<210>  4768
<211>  1212
<212>  DNA
<213>  Homo Sapiens

<400>  4768
cacctgcgcg agggcatgac actcctgaaa actgagttcg ctctgcatct gtatcaaagt       60

gtcgcagcgt gccgcaacga gactaacttc gtgatcagcc cagccggggt gtcactgccc      120

ttagaaatct tgcagttcgg cgcggagggg tccaccggcc agcagttagc ggacgccctg      180

ggatataccg tgcacgataa gagggtcaag gatttccttc acgccgtata cgctaccctg      240

cccaccagtt cccagggtac cgaaatggag ctggcctgct cactgttcgt acaggtgggc      300

acgcccctct ctccctgttt cgtggaacat gtaagttggt gggcaaacag tagcctggag      360

cccgcggatc tttctgagcc aaactccacc gcaattcaga catccgaggg cgcttcacgc      420

gagaccgcgg gaggtggacc ctcagaaggc cccgggggct ggccctggga gcaggtttct      480

gcggccttcg cacagctggt cctggtatct accatgagtt tccaagggac atggaggaaa      540

aggtttagct caactgatac tcagattttg ccatttacat gtgcctatgg ccttgtgctt      600

caggtcccaa tgatgcatca aaccaccgaa gtaaactacg gccaatttca ggacacggca      660

ggacaccagg tgggggtgct cgaacttcct tacctgggaa gcgcagtgag tctcttcctt      720

gtcctccctc gggacaagga cactcctctg agccacatcg aacctcatct tactgcaagc      780

acaatccact tgtggactac gtccttgcgt agggcccgga tggacgtatt cctcccacgg      840

ttccggatac aaaaccagtt caatttgaag tccatattga attcatgggg ggttacagac      900

ctgtttgatc ccttgaaggc caacctcaaa ggaatatctg ggcaagatgg cttctacgtg      960

tcagaagcaa tacacaaggc gaagatcgaa gtgctcgaag agggaactaa ggccagtgga     1020

gcaaccgcgc tgctgttgct gaagcgcagc aggattccta tttttaaagc tgatcggcct     1080

ttcatctact ttctccggga gcccaacacc ggcatcaccg tcttctttga taggatccag     1140

attatatacc aatgcctcag cagtaacaag ggcagttttg tacactaccc cctgaagaac     1200

aagcacagtt tt                                                         1212


<210>  4769
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  4769
accggtgcaa cattccctga ggaggctatt gcggatttat ctgtcaacat gtataatcgg       60

ctgcgcgcca ccggagagga cgagaacatc ctgttctccc ccctcagcat tgcgcttgcc      120

atgggtatga tggaattagg ggcccaaggt tccacacaga aggaaatccg ccatagcatg      180

ggatatgatt ccctgaagaa tggcgaagaa ttttccttcc ttaaggaatt cagcaacatg      240

gtgacagcaa aggagagcca atacgtgatg aagattgcca attctctctt cgtgcagaac      300

ggctttcatg ttaatgaaga gttcttacag atgatgaaaa aatacttcaa cgcagcagtc      360

aaccacgtgg acttcagcca aaatgtggcg gtcgcaaact acatcaacaa atgggtggag      420

aataacacaa acaacctcgt caaggacctg gtctcacccc gcgacttcga cgctgcaact      480

tacctcgctc tcattaacgc cgtgtatttc aagggtaatt ggaaatcaca gttcagaccc      540

gagaatacac gcaccttctc ttttactaag gatgacgagt ctgaagtgca gatccctatg      600

atgtaccagc aaggggaatt ttattacgga gaattcagcg atggcagcaa tgaggcagga      660

gggatatatc aggtgctgga aattccttat gagggtgacg aaatttccat gatgctcgtt      720

ctgtcccgcc aggaagtgcc cctcgctacc ctggagccct tagttaaggc ccagctggtt      780

gaagagtggg ccaattccgt gaaaaaacag aaggtggaag tgtatcttcc tagatttact      840

gtcgaacagg aaattgattt gaaggacgtc ctgaaagctc tcgggataac tgaaatcttt      900

atcaaggatg ccaacctcac gggtctcagc gacaataagg aaattttcct gagcaaagct      960

attcacaagt ccttcttgga ggttaacgaa gaaggatcag aagctgctgc ggtcagtggg     1020

atgattgcta tcagtagaat ggcagtgtta tacccccaag tcatcgtcga tcacccattc     1080

ttcttcctta tccgcaacag acgaacgggc accattctgt tcatgggccg ggttatgcac     1140

cctgaaacca tgaacacatc aggccacgac ttcgaggaac tc                        1182


<210>  4770
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  4770
atgagggcag ggttttccga ctttcaactc ataagagacc aggtcctgtt cctgcaagac       60

caggcccagc ggctgacaga gtggctccag ctgtctggtt ttgagaaccc tgtctctgaa      120

tcaaccactc tctgcctccg tgaaagagaa aagcggatcc ccacttgcgt ggcggtttgt      180

gtgcccagtc ccgggaccgt ccacaccgca ctcttacatc ccactaccct gagtcaatcc      240

aggagcagct cagaggcaaa aatgctgatt attcacaccg cc                         282


<210>  4771
<211>  699
<212>  DNA
<213>  Homo Sapiens

<400>  4771
aaagtcatgt ggttcagccc ggcaggaatg gggcacctct gcgttacaaa agatgggctg       60

cgcttggaag gcgaaagtga atttctcttt cccctctatg cgaaggagat tcactcccgc      120

gtcgacagtt ctctcttgct tcagtccacc cagaacgtta cagtgaacgc gcggaactca      180

gagggtgaag ttacgggccg cttgaaggtt ggacccaaga tggtcgaagt gcagaatcag      240

cagttccaga ttaattctaa tgatggaaag cctctcttta cagttgatga aaaggaggtt      300

gtggttggga cagacaagct gcgtgttact ggccctgaag gcgccctgtt tgagcacagc      360

gtagaaaccc ccctcgtgag ggcagaccca ttccaagacc tgcgactcga gagcccgact      420

cggagcctct ctatggatgc tcccagggga gtgcatatcc aggcacatgc ggggaaaatc      480

gaggccctga gccagatgga tatcttattt cacagttccg acggtatgct tgtgttagat      540

gcagagaccg tgtgcctccc taaactggtg caaggcacat gggggccgag cggaagctcc      600

cagtccctct acgaaatttg cgtctgtcca gacggaaaac tgtacttatc agtggccgga      660

gtttcaacga cttgtcagga acacaaccac atctgcctt                             699


<210>  4772
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  4772
aaggtgatga acttcaccgt tgacggcatg ggtaatttga gggttactaa gaagggcatt       60

aggctggagg gcattagcga gttcctgttg cctctgtatg tgaaagaaat ccactccaga      120

aaggacagcc ctctggttct ccaatccgac cgcaatgtca cggttaacgc caggaaccac      180

atgggacagc tgactggcca gctgacaatt ggagccgacg ccgttgaggc tcagtgtaag      240

agattcgaag tgcgagcgtc agaagacggt agagtgctct tcagcgctga tgaggacgaa      300

atcacaattg gagctgaaaa actgaaagtg actggcaccg agggagccgt tttcggtcac      360

agcgtggaga ctccacatat acgagcagag ccaagccagg acttacggct cgaatccccc      420

accagaagct taatcatgga ggcccctcgc ggcgtgcagg tgtctgcagc agcaggagat      480

ttcaaggcaa cctgtaggaa agaactgcat ttgcaaagca cagagggcga aatcttcctg      540

aacgccgaaa ccatcaagtt gggaaacctg ccaacgggga gcttctcatc ctcaagcccg      600

agttcctcaa gcagccgcca aaccgtatac gagctgtgtg tttgtcccaa tggcaaactt      660

tatcttagtc cggccggagt cggtagcacg tgccagtcaa gctccaatat ttgcctgtgg      720

agc                                                                    723


<210>  4773
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4773
gaggtttgta tggcatctcg gggcttgtct ctgttcccag agagctgccc tgacttctgc       60

tgtggaacgt gcgacgacca atattgttgt agcgacgttc tgaaaaaatt tgtatggtct      120

gaagagaggt gtgccgtccc agaggcatct gtgccagctt ccgttgagcc cgtcgagcag      180

ttaggctcag cactgcggtt tcgacctggc tacaatgacc ccatgtcagg a               231


<210>  4774
<211>  447
<212>  DNA
<213>  Homo Sapiens

<400>  4774
gctcgaggaa gagcagccaa cagaacgctg tcagcaggag gggcagctgt cggtggaagg       60

cgcgctggcg gcgccttagc gagaggaggc cgagagctga acggcaccgc ccgagcacct      120

ggcatacctg aggcaggtag tcggcgaggt cagcccgcag ccgccgtagc tgccgctgca      180

tcagctgcag tcacctatga gacatgttgg ggctattacg acgttagcgg acagtacgat      240

aaagagtttg agtgtaataa ctccgaaagc ggatatcttt attgttgcgg gacatgttat      300

tataggttct gctgtaaaaa aaggcacgag aagttggacc agcgccagtg cactaactat      360

caatcccctg tgtgggtcca aactccaagc actaaagtcg tgagtccggg tcctgagaac      420

aagtacgacc cggagaagga caagacc                                          447


<210>  4775
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  4775
cgaccttcaa atgcaactag tgctgagcct gctggaccat tgcccgctct cctggctcac       60

ctgcggcgcc tcaccggcgc cctgactggc ggcggggggg ccgcatctcc cggagctaac      120

ggtacacgca caggaccggc tgggggggcc ggggctgcag cacgcgctcc acccccagca      180

gagctgtgtc acggctatta cgacgtgatg ggtcagtacg acgctacatt caactgcagc      240

accgggagtt accgcttttg ctgcggaacc tgccattatc gcttttgctg tgaacacaga      300

cacatgaggc tggctcaggc ttcctgttcc aactacgaca ccccgaggtg ggcaactact      360

cctccaccac tcgccggggg tgccggcggc gctggcgggg caggaggagg acccggccct      420

ggacaggccg ggtggcttga gggcgggaga accggggggg ccggtggccg cggcggcgaa      480

ggtcctggtg gaagcactgc c                                                501


<210>  4776
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  4776
ggggccccag aagctcaggg ccccgccgct cctggcacca ccgcacccga gggaggagac       60

cgctgtcggg gatattacga cgtaatgggc cagtgggacc ctccttttaa ctgtagtagt      120

ggcgcatact ctttttgctg cggcacctgc ggttatcgct tctgctgtca cgatggtcct      180

cggcggctgg accaatctcg ttgctccaat tacgacacac ctgcatgggt gcagacaggc      240

aggcctcctg caagagcccg ggacacagca gccccaagag accccggtag agagcggtca      300


<210>  4777
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  4777
caggaaaggg ctggccatgg ccaactggct cagttggggg gggtcctgtt gttggcgggt       60

gggaacagat ctggtgctgc tagcggtgag gccagcgagg gagcagaggc ttcagacgcc      120

cctccaacta gggccccaac accagacttc tgccgtggct atttcgatgt gatggggcag      180

tgggacccac catttaattg tagtagcggg gatttcatat tctgttgtgg cacctgcggg      240

ttccggttct gctgtacctt caaaaagcga aggctgaacc agtctacgtg tactaattac      300

gatacaccct tatggcttaa caccggaaag cctcctgctc gaaaagacga cccccttcat      360

gatcccacaa aagataag                                                    378


<210>  4778
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  4778
gaggaggaac tccaagtgat acagccagat aaatcaattt ccgtagcagc tggtgaaagt       60

gctacccttc actgcactgt cacctcctta attccagtag ggccgatcca gtggtttagg      120

ggcgctggcc caggccggga gctgatctac aatcagaagg aaggccattt tccaagagtc      180

acaaccgtta gcgaccttac gaagcgaaat aacatggatt ttagtatcag gatcagcaat      240

atcactccag cagacgccgg gacatattac tgtgtaaagt ttcgaaaggg atcaccggac      300

cacgtagaat tcaagtctgg cgctggtact gagctgagtg tgagagcaaa gccaagcgca      360

cctgttgtat ccggccccgc cgctcgggct accccccagc acaccgtgtc atttacgtgc      420

gagtctcacg gatttagccc tagggacata accctgaaat ggttcaaaaa tggaaatgaa      480

ctttcagact ttcagacaaa cgtggacccc gcaggtgaca gtgtgagcta ctccatccac      540

agcaccgcga aagtcgtgct cactagggaa gacgtccact ctcaggtaat atgtgaggtc      600

gctcacgtaa ctctgcaggg cgacccactg cgggggaccg ctaatctgag cgaaaccatt      660

cgcgttcctc ctaccttgga ggtgacccag caacccgtga gggctgagaa tcaggttaat      720

gtcacttgtc aagtaaggaa attctatccc cagaggctgc agctgacttg gctcgaaaac      780

ggtaatgtat ctcggaccga gactgccagc acgctgacgg agaataagga tggcacgtat      840

aattggatgt cttggttatt ggtgaatgtt agtgcccatc gcgatgatgt gaagctgact      900

tgtcaggtag agcacgatgg tcagcccgct gtgtctaaga gtcacgacct gaaggtgtct      960

gcccacccca aagaacaggg aagcaacact gctcccgggc cggctcttgc tagtgctgct     1020

cctctt                                                                1026


<210>  4779
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  4779
ttagagaatt tcgcggcagc tatcccaggc caccgatgtt gggtgcacat gttagataac       60

aacaccggtt ccggcaacga aactggcatc ctttcagaag atgctctcct caggatttcc      120

attcctctgg acagcaacct taggcctgag aaatgcagaa ggtttgtgca cccccaatgg      180

cagctgctgc atttgaatgg gacaattcat tcaacatctg aggcggacac cgagccctgt      240

gttgacgggt gggtttatga ccagtcttac tttccaagca ccatcgtgac aaaatgggac      300

ctcgtatgtg attaccagag cttgaag                                          327


<210>  4780
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4780
atggtccttg acgaacccca tcactgcgcc gtggcctggg tcaaaaatca cacatttaat       60

ctttcagcgg ctgaacagct ggtcctgtcc gtcccactgg ataccgctgg gcaccccgag      120

ccatgtctga tgttcaggcc gcctcctgct aacgcgagtt tacaggacat cttaagccac      180

cgatttaacg agacacaacc gtgtgacatg ggctgggagt atcctgagaa ccgcttaccc      240

tccttgaaga acgagtttaa cttagtctgt gatagaaagc atcttaagga c               291


<210>  4781
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  4781
ggcttcacac ccgatcatag gtgccgtagt ccaggggttg ctgaactgtc attaaggtgt       60

ggctggagcc ctgcggaaga gctgaattac acagtacctg gacccggacc agcaggggaa      120

gcttctccac gacaatgtcg tcggtacgag gtggattgga accaatctac tttcgactgt      180

gttgaccccc ttgcttcatt agatacgaac cgctctcgct tacctcttgg gccctgtcgg      240

gatggctggg tgtatgagac tcccggctcc agtattgtta cagaatttaa tctggtgtgc      300

gctaacagct ggatgctgga t                                                321


<210>  4782
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  4782
ccaccgcacc actgtcgagg ccctgcgaat catacagaag caagcacgaa tgactcagga       60

gcatggctcc gcgctacaat cccccttgat cagctgggtg ccccagagcc ctgccgccga      120

ttcactaaac cacagtgggc cctgttatcc cccaatagct ctattccagg agctgctact      180

gaaggctgta aggatggttg ggtatacaac aggtctgttt tcccctctac cattgttatg      240

gaatgggatc tcgtgtgcga ggctcgaaca ctcagagac                             279


<210>  4783
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  4783
gtgtatcacc agacacagtt agagaatttt gccgcattca tactggacca taggtgctgg       60

gtacacattc tcgacaacga caccatccca gacaatgatc ctggcactct gagtcaagat      120

gctcttctta ggatctcaat tccgttcgac agcaatttgc ggcctgaaaa gtgtcggagg      180

ttcgtccatc cacagtggaa attgattcac cttaatggca cctttcctaa cacaagcgag      240

ccagataccg aaccctgcgt agatggttgg gtctatgatc agtcttcatt tcccagcaca      300

atcgtcacaa agtgggattt ggtctgtgaa tcccaaccac tgaat                      345


<210>  4784
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  4784
cagcccgccc ctcattgtcg cccagatccc acactcctgc cacctgcact ccgggctttg       60

cgcggccctg ccttactgga cgcggctata cctagactcg gaccaacacg ggcccctgcc      120

gaggccctgg gcgtcttaag cccttcttat ctggcccctt tgaccagggc tcctagacct      180

agctcctggg cttcctgcag cggagccgct gccgggccga cttggaacct ggtgtgtggg      240

gacggatgga ag                                                          252


<210>  4785
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  4785
aatgcccctc agcaggtgat catttcacat tataggcatg tactgggcgt ccccctggat       60

gatcggaagg caataaataa ctacgtgatt aatagtaccg acgaactccc aaccatttca      120

tactccatga atccgaaacc cacaccgtgg gcagaggagg agacagtggc ggctgcacag      180

ctgattacca tgctgtggtc t                                                201


<210>  4786
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  4786
gaatctgcga ccgcactttt ggaaagactg agcgaactgg cgctcggcgc cgcctccctg       60

accccccgag cccaggcacc agacatcctc aaggtcctca caaagcccct gacacatctg      120

atcgtacaac tcgactccga tatgatcatg tcaagcgcca ctggcaacgc aacaaatagc      180

agcttgatta agcactggtg tggtactaca ggtcaaccaa cccaggaaaa cagctcttgc      240

ggagcctttg ggccatgtac tgagaagaac tctaccgctc cggccgatag actcccgtgt      300

aggcacctgt ttgctgggac tgagttgaca gacctcgcc                             339


<210>  4787
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  4787
atggacccca tggagcttag aaatgtcaac atcgagcctg acgacgagtc ttcatctggt       60

gagagcgcac cggactcata tatcggcata ggcaactctg aaaaggctgc catgtcatcc      120

cagtttgcga acgaggacac cgaaagccag aagttcctca ccaacggttt tctggggaag      180

aagaagcttg ccgattacgc cgatgaacac caccccggca ctaccagctt tggaatgagc      240

agctttaact tgagcaacgc gatcatgggt tccggaattc tgggactgtc ttacgccatg      300

gcaaacactg gc                                                          312


<210>  4788
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  4788
tcttcctggg aggtaagcga gagaattcgg gagtgtaatt attaccagaa cctggccgtg       60

ccgcagggcc tcgaatacca gaccaatgag ccaagcgagg aacccatcaa gaccatccgc      120

aattggctca aggaaaagct gcatgtcttt tccgaaaagt tggaggagga agtgcaacag      180

ttggaacagc ttgcctggga tctcgaattg tggttggatg cccttctcgg ggaaccacac      240

caggaggagc actgctccac ctacaaatct cacctgtggg agtgggcatg ggcgctgggc      300

cgagaacaca aaggcggcga aggcctgtta gagatcagtc tgagcggagc tgagctg         357


<210>  4789
<211>  1239
<212>  DNA
<213>  Homo Sapiens

<400>  4789
gagccgggaa agttttggca tatagccgat ctgcatctcg atccagatta taaggtgtct       60

aaagaccctt tccaagtgtg tccttccgcc ggatcccagc ctgttccaga cgccgggcca      120

tggggagatt acctgtgcga ctcaccgtgg gcgctgatca acagttctat ctacgcgatg      180

aaagagattg agccggagcc agattttatc ttgtggacgg gcgatgacac tccacatgtc      240

cccgacgaaa agcttggcga agctgccgtt ctggaaattg tggaacggtt gacaaagttg      300

atacgcgagg ttttccccga cacaaaagtc tatgcggccc tgggcaacca tgatttccat      360

cccaaaaacc agttccctgc cggcagcaat aatatataca accagattgc ggagttgtgg      420

aaaccttggc tgtccaatga gagcattgcc ctgttcaaga aaggcgcatt ttattgtgag      480

aagctgcctg ggccctccgg tgccggacga atagtggtgc tcaatacaaa tttgtactat      540

accagtaacg cattgaccgc tgatatggct gatcctgggc agcagttcca gtggcttgag      600

gatgtgctga cagacgcaag caaggccggt gacatggtgt atatagtcgg ccacgtacca      660

cccggcttct tcgagaaaac ccagaacaag gcatggtttc gggaagggtt caacgagaag      720

tacctcaaag tcgtgcggaa acaccacaga gtcattgcag gacagttttt cggtcaccat      780

cacaccgaca gcttcagaat gctttatgac gatgccggcg tgccaatttc tgccatgttc      840

atcacacccg gagtgacgcc ctggaagact acactgcccg gagtagtgaa tggggccaac      900

aaccccgcta ttagagtctt cgagtacgac agagccaccc tgagcttgaa ggacatggtg      960

acctacttta tgaatctctc tcaggccaat gcccaaggta cccccagatg ggaactggag     1020

taccagttga ccgaggccta cggggtgccc gacgccagtg cgcattctat gcacaccgtt     1080

ctcgaccgca tcgcagggga tcagtctacc ctgcagcggt actatgtgta caattctgtc     1140

tcttactccg ctggcgtgtg tgatgaggct tgcagcatgc agcatgtgtg tgccatgcgg     1200

caggtcgaca tcgatgcata cactacctgc ctgtatgcc                            1239


<210>  4790
<211>  1596
<212>  DNA
<213>  Homo Sapiens

<400>  4790
gccgtcctcg ggttcctgca ggagcacggc ggcaaagttc gcaacagcga gcttttgtcc       60

aggtttaaac ccctcctgga cgcaggtgat cctcggggta gggccgctcg ccgggaccgc      120

ttcaaacagt ttgttaacaa cgtcgccgtg gttaaggagc tcgacggcgt gaaatttgtc      180

gtgcttcgca agaagccacg gcccccagag ccagaaccag cccctttcgg ccctcccgga      240

gcggccgctc aaccttctaa gcccacatcc acagtgctgc cgcggtccgc atctgccccc      300

ggcgctcccc ccctggtccg cgtaccccga cccgtggagc caccaggcga cctgggactg      360

cccaccgagc ctcaggacac tccaggcgga ccagcgagcg agcccgcaca gccacctggt      420

gagcgtagtg ctgaccctcc cctgcccgca ctggagctgg cccaggcaac agaaagacct      480

agcgctgacg ccgcaccccc ccctcgtgct ccttcagaag ctgccagccc atgctctgat      540

cctccggacg ccgagcccgg gcctggagcc gcgaagggtc ctccacagca aaaaccttgt      600

atgctgccag tccgttgtgt gcccgccccc gctaccttac ggctccgcgc agaagagcct      660

ggattgcgca ggcagctctc cgaggagcct agcccaaggt catctccact gctgttacgc      720

cgtctgtccg tcgaggagtc aggcctgggt ctgggtctcg ggcccggcag gtccccacat      780

ctgaggcggc tctcccgcgc cggaccacgc ttgctcagcc cagacgccga agaactgcct      840

gccgcgccac ccccaagcgc agttcccctg gagccaagcg agcacgagtg gttagttcgc      900

accgctgggg gaagatggac ccatcagctc catggcctcc tgctgcgtga tcgagggtta      960

gctgcgaaaa gagattttat gagcgggttc acggccctgc attgggcggc caaatccggt     1020

gatggtgaga tggcccttca gttggtcgag gtggcccgtc gttcaggggc tcccgtcgat     1080

gtcaatgcac gaagtcacgg cggctacact cctctgcacc tggccgcatt gcatgggcac     1140

gaagacgccg cggttctttt agttgtacga ctgggtgcac aggtgcatgt ccgcgaccac     1200

tccggccggc gtgcgtatca atatctgcgg ccaggttcct catatgcatt acgacgcctg     1260

ctcggagacc ctgggctcag gggaaccacc gagccagatg ccaccggggg aggcagcggc     1320

tccttggcag ctagaaggcc agtgcaggtc gccgccacaa tcctttcaag cactacttca     1380

gctttcctcg gcgtgctggc cgacgacctc atgctgcaag acttagccag aggcctgaag     1440

aagtcctcat ctttcagcaa gtttctgtct gcttccccga tggcccctcg caagaagact     1500

aagattcgcg gcggccttcc cgcttttagt gagattagca gaaggccaac accaggaccc     1560

ctggccggac tggttcccag cttccccccc accaca                               1596


<210>  4791
<211>  414
<212>  DNA
<213>  Homo Sapiens

<400>  4791
aaaatttacg agcgctgtga gctggcagca aggttagaac gggctggcct caatggctac       60

aaaggctatg gagtaggcga ttggctctgc atggcccact acgagagtgg attcgatacc      120

gcttttgtgg atcataatcc cgacgggtcc agcgaatacg gcatttttca gttaaacagt      180

gcttggtggt gcgataacgg catcaccccc accaagaacc tctgtcatat ggattgccac      240

gacctcctca acagacacat cctggatgat attcgctgtg ccaagcagat agtcagtagc      300

cagaatggcc tgtcagcctg gacaagttgg cgactgcatt gttctggcca cgacctgtca      360

gagtggctga aaggatgcga tatgcatgtg aagatagatc cgaaaatcca tccc            414


<210>  4792
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  4792
aggccgcgaa ctgtaatccc tggctcacca acagaaatac cattctcctc caaacaggag       60

gacatgtccg agctgcttga tgagatatta gtgcaggaaa tccttgacct taataagacc      120

acccctagtg agatgccctc tactgccagc acattaagta cccccctgca cgccggaatt      180

gatgagaact accaggccgg cgggagtgaa aactatcacg aactgctgga aaaccttcag      240

ttttcaccgg ggatagaggt caagatcagc aatgatgaag caaatgccaa tgctaatctt      300

cacggggatc ccagcgaaaa ctataggggt ccgcaagtca gcccaggatc cgaaaagtca      360

gttagctcca aagaaaagaa ttcaaaaaat actcagtacg aaaacttatc tatcctcgat      420

caaattttgc agaatattgg gcgctcttcc ggtaacattt ttcataaaga acagcagcgt      480

accagcgccc agcggaggag ccagggtagt cag                                   513


<210>  4793
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  4793
aggcatgtga accacagtgc caccgaggct ctcggagaac tgcgggaacg ggcccccggc       60

cagggcacga atggattcca actgctgaga cacgcggtga aacgggatct cctccctcct      120

cgaactcctc cataccaggt tcacattagc catcaagagg ccagaggccc ttctttcaag      180

atttgtgttg gtttcctcgg cccgcgatgg gcccggggct gttctacagg caatgagaaa      240

tatcacttac cttacgccgc aagggacctc cagacattct ttttaccatt ttgg            294


<210>  4794
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  4794
cgacatgtga accattccgc tacagaggct ttgggagagt taagggaaag ggcaccaggg       60

cagggtacta atggtttcca gctgcttcgc catgcagtta aacgagatct cctccctccc      120

cgcacacctc cataccaggt gcacatcagt catcgggagg caaggggccc gagttttagg      180

atttgcgtcg acttcttagg cccacgttgg gcacgcggct gctctacggg aaac            234


<210>  4795
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  4795
gcacctcagc aggaggctct tccagacgag accgaggtcg tggaggaaac cgtcgctgaa       60

gtgactgagg tgagcgtcgg ggctaacccc gtgcaagtgg aggtcggtga gtttgacgac      120

ggagccgagg agacagagga ggaggtggtc gcggaaaacc catgccagaa tcatcattgt      180

aaacacggga aagtctgcga gctggatgaa aacaacaccc ctatgtgcgt ctgtcaggat      240

cctacttcat gcccagcccc cattggtgag tttgagaagg tctgctctaa cgataacaag      300

accttcgact cctcttgtca ctttttcgct actaaatgca ccctcgaggg cactaaaaaa      360

gggcacaaac tgcatctgga ttatatcggg ccctgtaaat acataccacc ctgcttagac      420

agcgagctga cagaatttcc cctgcgaatg agggactggc tcaagaatgt gttggttacc      480

ctttacgagc gggacgaaga taataatctg cttacagaga aacagaaact gcgggtgaaa      540

aagattcatg aaaatgagaa acgcttagag gcgggggacc accccgtgga gctgctggca      600

cgcgattttg aaaagaatta taacatgtac atcttccccg tgcattggca attcgggcag      660

ctggaccagc accctattga tggctacctc tcacacactg agttggcacc tctgagagcg      720

cccctgattc caatggaaca ttgtacaacc agatttttcg agacatgtga tctcgataac      780

gacaaatata tcgccctcga cgagtgggct ggatgttttg gcattaagca gaaagatatc      840

gataaggatc tggtgata                                                    858


<210>  4796
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  4796
attgacttcc cactgccaat ggcttcagag cggggacagc tcgataagac tattgttgag       60

tgtcttaaga acgttaacaa gtgctggttc ctgtcctata ttaagccgag tgagcccatc      120

tgtggttcag accaagtgac ctattcatca gattgtcacc tgtgttctaa gattctgttt      180

gaaggactga atattaccaa gctgtacgac ggccaatgcg agaattct                   228


<210>  4797
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  4797
ggggttaata agatcgctga gaaaatctgc ggggacctga aggatccatg caaacttgat       60

atgaactttg gcagctgcta tgaggttcac ttccgttact tttataatag aacaagcaag      120

cgctgcgaga catttgtctt tagcggctgc aacggcaatc tcaacaattt taaattgaaa      180

atcgagcgag aagtcgcctg tgtcgccaag tataagcccc cgagg                      225


<210>  4798
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  4798
caaccactcg ggggcgagag catctgcagc gcacgcgcac tggccaaata ttcaataaca       60

tttacaggca aatggtcaca aaccgccttt ccgaagcagt accccctgtt tagaccgcca      120

gcacagtgga gtagcctgct gggcgccgca cacagttcag attatagtat gtggcgtaaa      180

aatcagtacg taagcaacgg actgagggat tttgcagaaa ggggggaggc gtgggctctt      240

atgaaggaga tcgaggctgc tggtgaagct ctgcagtccg tgcatgaggt atttagcgcc      300

cctgcggtcc ccagcgggac tggccaaaca agcgcggaac tcgaagtgca gcggcgacac      360

tccctggtaa gcttcgtggt gaggattgtg cccagcccag actggttcgt tggtgtagat      420

tccctcgacc tgtgcgacgg agatcggtgg agggagcagg cggcccttga cttgtatcct      480

tacgacgcag ggaccgacag cggcttcaca ttttcatctc ctaactttgc gaccatcccc      540

caagatactg ttacagaaat tacctcctca agtccaagcc accctgctaa ttcattttac      600

tatcctcgcc ttaaagcact ccctcccata gcccgagtca ctctcgtaag gcttagacaa      660

agccctcggg cattcatacc cccagccccc gttctcccca gcagagacaa tgaaattgtg      720

gactcagcct ctgtccccga aacccctctc gattgcgagg taagtttgtg gagttcatgg      780

gggctctgtg gaggccattg tggtaggttg ggtacaaaat cccggacacg ctatgtaagg      840

gtgcaacccg ctaacaatgg gagcccctgc ccagagctgg aagaagaagc ggagtgtgta      900

cccgacaatt gcgtg                                                       915


<210>  4799
<211>  546
<212>  DNA
<213>  Homo Sapiens

<400>  4799
ttcccagtgt acgattatga tcctagcagt ttaagggatg ccctgtccgc aagtgtcgtg       60

aaggttaact cacaaagctt gagcccatac ctgttccggg ccttcaggtc ttccttgaag      120

cgcgttgagg tgttagacga gaataacctt gtgatgaatc tggagttctc tatcagggaa      180

actacatgca ggaaggattc cggcgaagat cctgccactt gcgctttcca aagagactat      240

tatgtttcca ctgctgtctg tcgaagcaca gtgaaagtgt ccgcccagca agttcaagga      300

gtgcatgccc gctgtagttg gagtagcagc acaagcgaga gttacagctc cgaagaaatg      360

atcttcggcg acatgttggg atcccataag tggagaaaca attatctgtt cggcttaatt      420

agcgatgaat ctattagtga acagttttat gaccggtcct tgggcattat gcgacgggtg      480

ctccctcctg ggaaccggcg ataccccaac catcgccacc gggcccggat caacactgac      540

tttgag                                                                 546


<210>  4800
<211>  246
<212>  DNA
<213>  Homo Sapiens

<400>  4800
ctcgctaccg aggccggtca gaagccgtcc ctccggggat tgttagacgt cggaaacatc       60

caacacaggg ccgctcgggc aaggggctta accaggggag tgatcagggt cagcccccag      120

gaaaggagtc agcaaaacca gtccgcccct aaaggcccaa ccccgtctac aagacccaag      180

cccaggaccc tcggacctca ggcacacagc ctggcgttgc agagcgtgga tctgctgttc      240

cgcccc                                                                 246


<210>  4801
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  4801
atggagagcc tctctgagct gcagaaccca ctcctgcctc ggtccccggc tcatttgcat       60

gggccttatc cctatcccga gaccccccct tcatggtctt gtcaggagaa gctgtactcc      120

tatctgcttg gaggggctgg ccctgccggc gctcaccagc ttctggatcc gggttcactt      180

cagctcgccg tggaagcatg gtacaggcct agctgcctcc tggggcggga caaggtgaaa      240

gagccccgtg ctggaagttg tgaaaccagc tttaccgaag acagggagcc tcaggaaggc      300

cctccggagc agcccacggg accaggtcag gctgccgaaa atgttactat acaaacggta      360

tcctatgggg ttcaagagga gctgagggac caggaggacg atcaggaaga agaggagagc      420

gacgcaactt caaccgagtc agagagcgag gacaactttt taacattgcc cccacgggat      480

cacctt                                                                 486


<210>  4802
<211>  249
<212>  DNA
<213>  Homo Sapiens

<400>  4802
aactggctcg taaagtacga acacaaactc accctgcctg agccgcagca ggacgagata       60

ctgcaacgct tactgttctc tgaaatgaag atgaaagtac tggaaaatca gatgttcata      120

atctggaaca aaatgaacca ccacggacgc agctctaggc accggaattt tcccatgaaa      180

aagcaccgca tgcgtagaca cgagagcatt tgcccgacgc tctcagactg cacctcatcc      240

agtccttcc                                                              249


<210>  4803
<211>  828
<212>  DNA
<213>  Homo Sapiens

<400>  4803
gatagcgagg aagatgagga gcataccatc atcaccgata cggaattgcc tcccttaaaa       60

ctcatgcact ccttttgcgc ttttaaagca gacgatggac cctgcaaggc cataatgaag      120

cggttttttt tcaacatatt cactcgccaa tgcgaagaat tcatctacgg cggttgtgaa      180

ggaaatcaaa ataggttcga gagccttgag gagtgtaaga agatgtgcac ccgagataac      240

gccaatcgta ttataaagac cactctgcaa caagaaaagc ctgacttctg ctttctcgaa      300

gaagatcctg ggatctgccg gggttatatc accaggtact tctacaataa ccagacaaag      360

caatgtgagc gcttcaagta cggcggatgc ttgggcaata tgaacaattt tgaaacgctg      420

gaggaatgca agaatatttg cgaagatgga ccaaatggtt ttcaagtgga caattacggt      480

actcaactca atgccgtgaa taattcactg actcctcagt ccactaaagt gccatcactc      540

ttcgagttcc acgggccatc ttggtgcctg actcctgctg accgaggatt gtgcagagca      600

aatgagaatc gattctatta taatagcgtg atcggaaaat gccgcccttt caagtattcc      660

ggatgcggcg gaaacgagaa taacttcact agcaaacagg agtgtttgcg ggcctgcaaa      720

aagggcttta tacagaggat atctaagggc ggccttatca aaactaaaag gaagaggaag      780

aaacaacggg tcaaaatcgc ctatgaagag atctttgtta agaatatg                   828


<210>  4804
<211>  804
<212>  DNA
<213>  Homo Sapiens

<400>  4804
atgggcgaat ctgctgccgc aacagcgtcc ttgtttcaga ggagaagaag gggaagaggg       60

ggaagagtga cattccctgg gggattgaag ggcagtgcac gattcctttc cttcggaccc      120

ccatttcctg ctccacctgc acctccgttc cctgctgccc ctgggccgtg gctgcgaaga      180

ccactgtttt ctctcaaatt gagcgatact gaggatgtgt ttcccaggcg tgcaggccct      240

ctggaggtcc cagccgatag cagggtattc gtgcaggccg ctctcgcccg gccatccccc      300

aggtggggtc tggctttaca tcgatgctcc gttacgccct ccagtcgccc cgctcccggc      360

cctgccctgg cactgctgag agaggggtgc ccagcagata cctccgtcgc ctttccaccg      420

cctccccccc ccagccccgg tgctgcccga cccgcccggt ttagttttcg tctgcgtcca      480

gtgttcaatg ccagcgttca gttccttcat tgtcagttgt caaggtgtcg ccgcctccgt      540

ggcgttagac gggcgcccgc cccgttaact cctcctccac ctccccctcc atctcgatgt      600

ttaccccagg acgaagcgtg cgccgatacc ggttccgggt ccgctgaagg tcttgcagcc      660

gacggccccc accttcacac actgacccaa cctatagtcg tgaccgtgcc acgtccgcct      720

ccccgccctc caaaaagcgt gccaggacgg gctgtgcgcc ccgagcctcc ggcccctgcg      780

cctgcagcac tggaacccgc ccca                                             804


<210>  4805
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  4805
ctcctcgatg tatggtacct cgtcagatta ccatgtgccg tactccgcgc gcggctcctc       60

caacctcgag tgcgggactt gcttgcggag cagagattcc cgggccgggt cctgccatcc      120

gacctcgacc tgttacttca catgaataac gctcgctact tacgggaggc cgatttcgca      180

agggtggccc acttaaccag atgcggtgtt ttaggcgcac tgcgggaact ccgagcgcac      240

accgtgcttg ccgcttcctg tgcacgtcat cgcaggagtc tccggctgct ggaaccattc      300

gaagtcagaa ctaggctttt aggctgggac gacagggcat tctacctgga ggcaaggttt      360

gtctcattac gtgatggctt cgtgtgcgcc ctcctgcgat ttcggcagca cctgttgggc      420

accagccctg aaagagtcgt ccagcacctg tgccaaaggc gcgtcgaacc ccccgagctc      480

ccagcggacc tccagcactg gatcagctat aatgaggcat cttctcaatt actccgcatg      540

gaatcaggcc tcagcgacgt gactaaggac cag                                   573


<210>  4806
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  4806
atgtggtacg ttagcacaag gggcgtggcc cctcgcgtga actttgaagg tgcgctgttt       60

agtggttacg cacctgacgg aggattattt atgcctgaag agctgcccca gcttgacagg      120

gggaccttgt gccagtggag taccctgagc tatcctggcc tggtgaaaga actgtgcgca      180

ctcttcatag gaagtgagtt gttgcctaaa gacgaactca atgacctgat agaccgtgcg      240

ttctcacgct tccggcaccg cgaagtagtc cacctgtcaa ggctgcgcaa cgggcttaat      300

gtgctcgagt tgtggcacgg ggttacttac gcattcaagg acctcagcct gagctgtact      360

acacagttcc tgcagtactt tcttgaaaag agggagaagc atgtcaccgt cgtggtgggc      420

acatccggag acacgggctc cgcggcgatt gaatccgtgc aaggagcaaa gaacatggac      480

attattgtac tcctgcccaa ggggcactgt accaagattc aggagctcca gatgacaacc      540

gtgctgaagc agaacgtgca tgtcttcggg gtggaaggaa atagcgacga attagatgaa      600

cctatcaaga ctgtgttcgc tgacgtggct tttgtcaaaa agcacaacct gatgtccctc      660

aactcaataa attggtctag ggtgttggtc caaatggctc atcatttctt cgcctacttt      720

cagtgcaccc cttccttgga cacccacccc ttgccactgg tcgaagtcgt agtgcccacc      780

ggcgcagcag ggaatttggc cgccggatat attgcacaaa agatcggcct gcccattagg      840

ttagtggtcg ccgtcaatcg aaacgatatc attcacagaa cagtgcaaca gggtgatttc      900

tccctgtccg aagcggtcaa gagcaccctg gcaagtgcaa tggatataca ggttccttat      960

aacatggaac gggttttctg gctgcttagc ggcagcgatt ctcaggtgac cagggccctc     1020

atggagcagt ttgagcggac gcaaagtgtc aacctcccta aagagctgca tagtaagctg     1080

tcagaagcag tcaccagcgt aagcgttagc gacgaggcga ttacacagac catggggcgg     1140

tgctgggacg aaaatcaata cctgctgtgt ccacactccg ccgtggcagt caattaccac     1200

taccagcaaa tcgatcgcca acagccaagc acaccccgct gctgtctggc tccggcatct     1260

gcggccaagt tcccagaggc cgtcctcgca gccgggctga cccccgaaac ccccgccgag     1320

atagtagccc tggaacacaa agaaacaaga tgtacactga tgcggagggg ggataactgg     1380

atgctgatgc tccgggacac gatcgaggac ctgagtcgtc agtggcggag ccacgccttg     1440

aatacatccc ag                                                         1452


<210>  4807
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  4807
agtcccgcac ctcctgcctg tgacctgcgg gtgcttagca agctgctgcg ggactctcat       60

gtgctccatt ctcgcttatc ccagtgtcca gaagtgcatc cgctgcccac cccagtattg      120

ttaccagccg ttgatttttc tttgggcgaa tggaagacgc aaatggaaga gacaaaggcc      180

caggatattc tgggtgctgt gacattgctt cttgaagggg tgatggccgc aaggggccag      240

ctgggtccga cttgccttag ctctctcctc gggcaactct caggacaggt gcggctgctg      300

ctgggagccc tccagtccct ccttggcacg cagctgcccc cccagggcag gacgactgct      360

cacaaggatc ccaatgcaat cttcctgagt tttcagcacc tgctccgagg caaagtccgc      420

ttccttatgt tggtgggggg ttccacgttg tgcgtgaggc gcgcgcctcc tacaactgcc      480

gtcccgtcca ggacctctct cgtcctcacc ttgaacgagc ttcccaacag aacctcaggg      540

ttactcgaaa ccaactttac ggccagcgcc cggactactg gcagcgggct gttgaagtgg      600

cagcaagggt tcagggctaa gatccctggt ctgctgaatc aaaccagccg gtcccttgat      660

cagatccccg gctacctgaa ccggattcat gaattgctca acgggactcg agggctgttc      720

cccggccctt cccggcgaac tctgggagcc cccgatatct ccagcgggac gtccgataca      780

ggttctttac ccccgaatct gcaacctgga tactcaccca gccctacaca ccccccgacg      840

ggtcagtata ctctcttccc tttgccacct actctcccta ccccagttgt gcaactccat      900

ccattacttc ctgacccctc agcccccacc ccaactccaa ccagtccact gttaaacacc      960

agctatactc atagtcagaa cctctcacag gaggga                                996


<210>  4808
<211>  822
<212>  DNA
<213>  Homo Sapiens

<400>  4808
gctgaggtct ttgggaattc cagtgagggg ctgattgagt tctctgtagg caaatttcgg       60

tactttgagt tgaatagacc ttttcccgag gaggcaatcc tgcacgacat ttcaagcaac      120

gtgacatttc tgatcttcca aattcatagt cagtatcaga acactacagt ttctttctct      180

ccaactctgc tttcaaattc cagtgagaca ggaaccgcat ccgggcttgt ctttattctt      240

aggccggagc agtccacttg cacgtggtat ctgggcactt caggaattca gcctgtgcaa      300

aacatggcca tcctgctgtc ctatagtgag agagaccctg tccctggggg atgtaacctc      360

gagttcgatc ttgacatcga cccaaatata tatctggagt ataacttctt cgagacaact      420

atcaagttcg ccccagcaaa cctggggtat gcgagaggcg tcgaccctcc accctgtgac      480

gctgggacag atcaagactc ccgatggaga ctccaatatg atgtgtatca gtattttctc      540

cccgagaatg acctgacgga ggaaatgctg ctgaaacact tgcaacgtat ggtgtccgtg      600

ccccaggtaa aagcgtctgc gctgaaagta gtgaccctca ctgctaacga taagacctct      660

gtgagcttta gtagcctgcc cggtcaaggg gtgatctata acgtgatagt gtgggaccct      720

tttctgaata cgtctgccgc ttacattcct gcccacacct acgcctgtag ctttgaggcc      780

ggggaagggt cctgtgcctc cttagggcga gtgagtagta aa                         822


<210>  4809
<211>  585
<212>  DNA
<213>  Homo Sapiens

<400>  4809
gatgagcatg aacacacata ccaagataaa gaggaagtcg tcctctggat gaacacagtg       60

ggcccatatc acaataggca ggagacatac aaatatttct ccctcccttt ctgtgtgggg      120

tcaaagaaat ctatttccca ctatcacgag acgctcggtg aggcactcca aggagttgaa      180

ttggaattct ctggcctgga tattaaattc aaagatgacg tgatgcccgc cacttattgc      240

gaaattgatc tcgataaaga gaaacgagac gcgtttgtct acgccatcaa gaaccactac      300

tggtatcaga tgtatatcga cgaccttcca atctggggca ttgtcgggga ggccgacgag      360

aacggggagg actactacct ctggacatat aagaaattgg agataggatt taacggcaat      420

cggattgtgg atgtaaatct tacgtccgaa ggaaaggtga agctggttcc caatacaaag      480

atccagatgt cctatagcgt gaagtggaag aagagtgacg tgaagtttga agacaggttc      540

gacaagtacc tggaccctag ctttttccag catcgtatcc actgg                      585


<210>  4810
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  4810
aggtccgtac ctcttaaagc aacctttctc gaggatgtcg ccgggagcgg cgaggctgag       60

ggttcctcag cttcatcccc ctcactcccc cctccgtgga cgccggcctt gagcccgaca      120

tccatgggcc ctcagccaat cactctgggt ggaccgagtc ctcctaccaa ttttcttgat      180

ggaattgtgg atttctttcg gcagtatgtg atg                                   213


<210>  4811
<211>  405
<212>  DNA
<213>  Homo Sapiens

<400>  4811
atgcagcctc ctccacccgg accactgggc gattgcctga gagattggga agatttacaa       60

caggattttc aaaatataca ggaaacccac cggctgtacc gacttaagtt ggaagaattg      120

actaaactgc agaacaattg taccagcagc ataaccaggc agaaaaaacg gctgcaagaa      180

ttggcattag cgcttaaaaa atgtaagcca tctttacctg ctgaagccga gggcgctgcc      240

caggaactgg aaaaccagat gaaggagaga caggggctgt tcttcgatat ggaggcttac      300

ctgcccaaaa agaatggcct ttatctcagc ctggtactgg gcaatgttaa tgtaactctt      360

ctgtccaaac aagccaaatt cgcatacaaa gatgaatacg aaaaa                      405


<210>  4812
<211>  558
<212>  DNA
<213>  Homo Sapiens

<400>  4812
aagaccccta aggaacgcac tttggagctg agctgcctgg aggtttgtct ccaatccaac       60

ttcacttaca gccttagctc acttaatttc tcctttgtga cattcctgca gccagtgagg      120

gagacacaaa taattatgcg gatcttcctt aacccatcaa atttccgtaa ttttacccgc      180

acttgtcaag atattaccgg agaattcaag atgtgtagca gctgtctcgt ttgcgagtcc      240

aagggaaata tggatttcat tagccaggaa cagactagta aagtgttgat acgccgcggc      300

tctatggagg taaaggctaa cgacttccac agcccctgcc agcacttcaa ctttagcgtt      360

gccccactcg ttgatcacct ggaggaatac aacacaacct gccacttgaa aaatcatacc      420

ggccgctcta ccatcatgga ggatgagcca agtaaggaga agtcaatcaa ctacacatgc      480

aggatcatgg agtatcccaa tgactgcatc cacatcagcc ttcacctcga aatggacatc      540

aaaaacatca catgcagt                                                    558


<210>  4813
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  4813
ggcgccgctg acgctccagg gctcctgggc gtcccaagca acgcatcagt gaatgccagt       60

tctgcagatg agcccattgc tccacggctc cttgcctctg ctgcaccggg cccgccagag      120

cgcccaggac cagaggaagc cgccgccgcc gctgctccat gtaacataag tgtgcaacga      180

cagatgctgt cttctctctt ggtgagatgg ggaagaccac gcggctttca atgcgatctt      240

ttactcttca gtacgaacgc acacggccgc gctttctttg cggctgcgtt ccaccgcgtt      300

gggccccccc tcttgatcga acacctgggg ctggcagcag gcggagcgca acaggacttg      360

aggttatgtg tggggtgcgg ctgggtgcgg ggtcgtcgta ccggtcggct taggcctgct      420

gctgccccca gcgccgccgc cgcaacagcc ggtgcaccca ctgcccttcc cgcctatccc      480

gctgctgaac cccccggccc cttgtggctg cagggagagc cattgcattt ctgttgcctg      540

gacttctctc tcgaggaatt gcaaggagag ccgggctggc ggctcaacag aaaaccgatc      600

gagtctacat tggtggcctg cttcatgacc                                       630


<210>  4814
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  4814
atctttacag atcactggta cgagaccgat ccccgacgac acaaggaatc atgcgaacgt       60

tccagggccg gagcggaccc cccagaccag aaaaataggt taatgccttt atctcacctg      120

ccgctgaggg actccccccc actggggcga cgcctgctgc ccggcggacc aggccgggct      180

gatcctgagt cctggcggtc tttactcggg ctcggcgggc ttgacgccga gtgtggccgt      240

ccactttttg caacttatag cggcctctgg aggaaatgct actttctggg gattgaccgg      300

gacatcgata ccctgatctt gaagggtatt gcgcagaggt gcaccgccat taagtaccat      360

tttagtcagc ccatccgtct ccggaacata cccttcaatc tcacaaagac tatccaacag      420

gatgaatggc acctcctcca cttgagaagg atcactgcag gt                         462


<210>  4815
<211>  444
<212>  DNA
<213>  Homo Sapiens

<400>  4815
gtcgccatct gtagcgacca ctggtacgaa actgacgcac ggaagcaccg tgacaggtgc       60

aaagctttca atacccgccg cgttgatcca ggcttcattt acaataataa caacaacctt      120

cctctgagag ccagcaggag caggctggat cgatgggaag gaaaacttct ccgggcaagg      180

aaccggagac agttgttcgc aatgtctccc gccgacgagt gttcacgaca atacaacagc      240

accaatatgg gtctctggag aaagtgtcat cggcagggat ttgaccctga aattgctgct      300

ctgattagaa aaggagagat tgagcggtgc acatacatca agtaccatta ctcctctgcg      360

acaataccaa ggaacctgac ttttaatatc accaagacaa tcaggcagga cgagtggcac      420

gcgctgcact tacgacgcat gact                                             444


<210>  4816
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  4816
taccgaacga ttacggactt ccgcgaaaaa ttaaagcacc ctgtgatgtc tgttagctat       60

aaagaggtgg acagatatga cgctcccggc atcgctctgt acccaggcca ggcacagctt      120

ctgtcctgta agcatcatta tgaggtgata ccgccactca ccagcccagg tcaacccgga      180

gacatgaact gtactaccca gagaatcaac tacactgatc cgttcagtaa tcagacagtt      240

aagtctgcac ttatagtgca gggacctcgg gaggtgaaaa agcgggagtt agtttttctc      300

cagttccgac tgaataaaag ctctgaagac ttttcagcca tagattatct cctctttagc      360

agttttcaag agtttctcca gtctccaaat agggttggtt ttatgcaggc atgcgagtcc      420

gcgtactcta gctggaaatt ttctgggggt ttccgcacct gggtgaaaat gagtttggtt      480

aagaccaagg aggaggacgg cagagaagcc gttgagttca gacaagaaac atcagtcgtt      540

aattacatcg atcaaaggcc tgcggctaaa aaaagtgccc aactgttttt cgttgttttc      600

gagtggaaag accctttcat tcagaaggtg caagacattg tgacggct                   648


<210>  4817
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  4817
agctttttac tcactcatcg aacaggcctc cggtccccag atattcctca ggattgggtc       60

tccttcctgc ggtctttcgg acagctgacg ctctgccctc ggaatggaac cgtgaccgga      120

aagtggcgag gctctcacgt cgttggactg ttgacaactc tcaacttcgg agacggcccg      180

gaccgcaaca aaaccagaac ttttcaagcc acggttctgg gcagccaaat ggggttgaag      240

gggtccagcg ccggtcagct tgttcttatt accgccagag tgacaactga acgaactgcc      300

gggacttgtc tgtacttcag tgccgtgcca ggaattctgc catctagcca accaccgatt      360

agttgctcag aggaaggagc cggaaatgca accttgagtc ccaggatggg agaagagtgt      420

gtctcagttt ggtcccacga ggggttggtc ctgaccaagc tgctgacatc cgaagagttg      480

gccctctgcg gttcccgt                                                    498


<210>  4818
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  4818
gactattggt acatcttgga agtggccgac gccggaaacg gttctgcttg gccgggaagg       60

gccgaactgc tttctagtca ttctgggttg tggaggatat gcgaaggaca gaacggatgt      120

atccccttgg tggacccatt cgctagtgag tcactggacg tctctacttc agtgcagcat      180

ctcatcctgc tccatcgagc a                                                201


<210>  4819
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  4819
aacaagtcca gtgaggacat ccgttgcaaa tgcatttgcc ctccctaccg taacatctcc       60

ggacacattt acaaccagaa cgtcagtcag aaagattgca attgcctcca tgtagtagaa      120

ccaatgccag tgccgggaca cgacgtcgaa gcatattgtc ttctctgtga gtgtagatat      180

gaagagcgca gcacaactac cattaag                                          207


<210>  4820
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4820
atggactccc cctctctcag ggaactgcaa cagcctctgt tggaagggac agaatgtgaa       60

acacccgctc agaaacctgg tcgtcatgag ctcggttctc cactccggga gattgcattc      120

gccgagagct tgagagggct tcagtttctc agccccccac tgccttcagt cagcgccgga      180

ctgggggaac caaggccgcc tgacgtggag gacatgtcat ccagcgatag tgacagcgat      240

tgggatggtg gatcccggct gtccccgttt cttccccatg accacctcgg t               291


<210>  4821
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  4821
tcatatgtac cgagtgttgc cccaaccgcc gcacactcag tgcgagtgcc ccacagcgcc       60

ggtcattgcg ggcagagagt gctggcgtgt agcctgcccc aagtctttct gaaaccctgg      120

atcttcgtag aacacttctc tagctggctt tccctggagc tgttcagttt tttacggtat      180

ttggggaccc tgctgtgtgc gtgtggtcat cggcttcgag aa                         222


<210>  4822
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  4822
gaggatgata aatctttcta ttacctggct tcctttaagg tgacaaatat taagtacaaa       60

gaaaactatg gcatccggtc ttcccgggaa tttatcgaga ggtcacacca gatcgaacgc      120

atgatgagcc gcatcttcag gcacagttct gtcggtgggc gctttattaa gtcccacgtt      180

atcaaattat ccccagatga gcaaggggtg gacatcctga tagtgctgat cttcaggtat      240

ccctcaacag acagcgctga gcaaattaag aagaagatcg aaaaagcctt gtatcagtca      300

cttaaaacga agcaactctc cctgaccatc aataagccct cttttcgatt aacacccatt      360

gattccaaaa aaatgaggaa cctgctgaac agcagatgtg gaatccgaat gacaagctcc      420

aacatgccac tccctgccag tagtagcact caacggatcg tccagggacg cgagaccgct      480

atggaagggg agtggccttg gcaagcttct ctccagctta ttggatctgg ccatcagtgt      540

ggagcctctc tcatctctaa cacatggctc ctcaccgcag cacactgctt ttggaagaat      600

aaggatccca cccagtggat cgctaccttc ggggccacaa ttacgccccc cgctgtaaaa      660

cgcaacgtca gaaaaattat tttgcacgaa aattatcatc gggagacaaa tgaaaacgac      720

atagctctgg tccaattatc tactggggtg gaattttcca acattgtgca aagagtgtgc      780

ctgcccgact ctagtatcaa gctcccccct aaaacgtccg tctttgtcac tggattcggc      840

tccatcgtgg acgatggacc aattcagaat acactgcgtc aagcccgagt ggagacaatc      900

tctaccgatg tctgcaaccg aaaagacgtg tatgatggct taattacccc cggtatgctg      960

tgtgctggct ttatggaggg aaaaatcgac gcttgcaaag gcgattctgg aggtcctctc     1020

gtgtacgaca atcacgatat ctggtatatc gttgggatcg tatcttgggg tcaatcatgt     1080

gctctgccaa agaagccggg agtctacacc cgggttacca aatatagaga ctggatagct     1140

tctaagactg gtatg                                                      1155


<210>  4823
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  4823
actgccggtc cagaggaagc tgccttgccg cctgagcaga gtcgtgtcca gcccatgacc       60

gcaagcaatt ggactctcgt catggaggga gaatggatgc tgaaattcta cgccccatgg      120

tgcccttctt gtcaacagac cgattcagaa tgggaagctt ttgcgaaaaa tggggaaatc      180

ctgcaaatta gtgtcggtaa agtcgatgtt atccaggaac caggactgag tggacgtttc      240

ttcgtcacta cattgcccgc cttcttccat gcaaaggatg ggattttccg aagatacaga      300

ggtccaggga tattcgaaga cttgcagaac tatatcctgg agaagaagtg gcagagcgtt      360

gaacctctca cgggatggaa gagccccgca tctctcacta tgagcggtat ggccggtctc      420

ttctcaatta gtggaaaaat ttggcacttg cacaattact tcacagtgac actgggcatc      480

cccgcatggt gttcttac                                                    498


<210>  4824
<211>  801
<212>  DNA
<213>  Homo Sapiens

<400>  4824
aagcactttt ggcctgaggt gcctaaaaaa gcatatgaca tggagcatac tttttactcc       60

aacggggaga agaagaaaat ctacatggag atcgaccccg tgacccgcac cgaaattttt      120

cggagtggga atgggacaga tgagaccctt gaagtccatg atttcaaaaa cggttacacc      180

gggatatact tcgtgggcct gcagaaatgc ttcatcaaga cccagatcaa agtaatcccc      240

gaattctctg agcctgaaga ggagatagac gagaatgagg aaattaccac aaccttcttt      300

gaacagagtg tgatctgggt acccgcggaa aagcccatcg agaataggga ctttctcaag      360

aatagcaaaa tcttggaaat atgcgataac gtgactatgt actggattaa tcctacctta      420

attagcgtct ctgagctgca ggatttcgag gaggaaggtg aagaccttca cttccccgct      480

aacgagaaaa aggggataga acagaatgaa cagtgggtcg tgccccaggt caaggttgag      540

aaaaccagac acgccagaca ggcttctgaa gaagagttgc ccattaatga ctacaccgag      600

aatgggatcg aatttgaccc catgctggac gagcggggct attgttgcat ctactgcagg      660

aggggaaacc ggtactgtcg gagagtgtgc gagcctcttt taggttacta tccttaccct      720

tactgctacc agggaggcag agtgatctgc cgcgttatta tgccatgcaa ctggtgggtg      780

gctcgcatgc tggggagggt c                                                801


<210>  4825
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  4825
gcttgggatc tcgcatccct taggtgtaca ctgggcgctt tctgtgagtg cgattttcgg       60

ccggatctcc cgggtctgga atgtgatctg gcacaacatc tggctgggca gcacctggca      120

aaagccctgg tcgtgaaggc tctgaaggcc tttgtgaggg atcccgcccc cacaaaacca      180

ctggtgctga gcctgcacgg ctggaccgga actggaaaaa gctacgtcag ttcactgttg      240

gcccactact tattccaggg cgggctcaga tctcctcggg tgcaccattt cagtccagta      300

ctccatttcc cacatccatc acacattgaa agatataaga aagacctcaa gagctgggtt      360

cagggcaatt taactgcttg cgggcgctct ctctttctgt tcgacgagat ggacaagatg      420

cctccaggac ttatggaggt gctgaggccc tttctgggta gtagctgggt ggtttacggc      480

acaaattaca gaaaagccat tttcatcttc attcgttggc tgctcaaact ggggcaccat      540

gggcgcgcac cccctaggcg gagtggagcc ttgccacctg ctccagccgc cccgaggcca      600

gccctccgtg cacagcgcgc tggacccgcc ggccccggag cgaagggt                   648


<210>  4826
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  4826
gggccagcgg aagaggccgg cgcgcactgc cctgagtctt tgtggcccct gcctccacaa       60

gtgtctccta gagttaccta tacaagagtt agtcctgggc aggccgaaga cgtgaccttt      120

ctgtatcacc cgtgtgcaca tccttggctg aagctgcagc tggccttgct ggcttatgca      180

tgtatggcta acccttctct gacacccgat ttttccctga cccaagatag acctttggtg      240

ttgactgcat ggggactcgc tctggagatg gcgtgggtcg agcctgcatg ggcagcccac      300

tggctgatga ggaggcggcg tcgcaaacag agaaaaaaga aggcctggat atattgcgaa      360

agtttaagtg ggccggcacc ctctgagcca acccctggga gaggcagact gtgtaggcga      420

ggttgtgtcc aggccctggc cctggcattc gcactccgta gctggagacc gccagggaca      480

gaagtcacgt cccagggacc acgacaacca agcagttcag gagccaagag acgcagatta      540

cgagctgccc ttggccccca gccaaccaga tctgcactga ggttcccctc cgcctcaccg      600

gggtccttaa aggcaaagca gagcatggct ggcattccag gtagggaaag caatgctcct      660

agcgtgccta ccgtaagtct gttgccaggc gctcccggag gaaatgcatc ctctcgcacc      720

gaggctcagg tccctaatgg ccaaggttct cccgggggat gtgtgtgctc cagccaggca      780

agccccgccc cccgagctgc cgcaccccct cgggccgcgc gcggacctac accccgcacc      840

gaggag                                                                 846


<210>  4827
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  4827
attgtaggtg gccaagaggc accacgcagc aaatggccgt ggcaggtgtc cttacgcgtg       60

cacgggccat actggatgca cttttgcggc ggctcactga ttcaccctca gtgggtactg      120

actgccgccc attgcgtggg acccgatgtg aaggatctgg ctgcgcttcg cgtccagctt      180

agagagcaac atctgtacta tcaggatcaa ctgctgcctg tcagcagaat tatagttcac      240

cctcagttct acactgcaca gatcggcgct gacatcgcac ttctggagct ggaggagcca      300

gttaacgtat cttcccatgt acataccgtg actctgcccc ccgcctctga aacttttcca      360

cccggaatgc cctgctgggt taccggatgg ggcgacgtcg acaacgatga gaggctccct      420

ccccctttcc ctttgaaaca ggtgaaagtt cctataatgg agaaccacat atgcgatgca      480

aaataccatc ttggcgccta tacaggggat gatgtgcgaa ttgtgagaga cgatatgctg      540

tgcgcaggga atacccgccg tgatagctgt cagggcgatt ccggtggacc actggtctgt      600

aaagtcaatg gcacatggtt gcaggccggt gtggtatcat ggggagaggg ctgtgcccaa      660

ccaaaccgtc ccggtattta tacgcgtgtt acctattatc tggattggat tcatcactac      720

gttcccaaaa agcct                                                       735


<210>  4828
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  4828
atcgtcgggg gccaggaggc ccctaggtcc aagtggcctt ggcaagtctc actccgggtg       60

cggggcccgt attggatgca tttctgtggc ggatctctta tccatcctca gtgggtcctt      120

actgctgcac actgtgttga gcctgatatt aaagatctgg ccgccctgcg cgtccagctg      180

cgcgaacagc acctctacta ccaggaccaa ctccttcctg tctcacgcat catagtgcac      240

cctcaattct acatcatcca gacaggggcc gatatcgcat tgctggagct tgaagagccg      300

gtaaacatct ctagccatat acatacagtg accctgcctc cagcatcaga gacctttccc      360

cctggaatgc cctgttgggt gaccggctgg ggcgacgtgg acaacaacgt gcatctgccc      420

cccccatatc ctcttaagga ggttgaggtc ccggtggtcg agaaccacct gtgcaacgcg      480

gaatatcaca caggtttaca cactggacac tcctttcaga tagtgaggga cgatatgctg      540

tgtgccgggt cagaaaacca tgatagttgc cagggggact ctggcggccc cctggtttgc      600

aaggttaatg ggacc                                                       615


<210>  4829
<211>  1425
<212>  DNA
<213>  Homo Sapiens

<400>  4829
aggcctcaac caccagacgg gggccagtgc cgccccccag gaagtcagcg tgacctcaat       60

tcctttctgt ggaccatccg gcgggaccca cccgcctact tattcggcac aattcatgtc      120

ccgtacacta gagtttggga ttttatcccc gataactcta aggcagcctt ccaggccagc      180

acgagggtgt attttgagtt ggacctgaca gacccataca caataagcgc tttagccagt      240

tgccaactgc tgccgcacgg ggaaaatctt caagatgtgt tgccccacga gctgtactgg      300

cgtctgaaac gacatttgga ctatgttaag ttgatgatgc cttcctggat gacaccagcc      360

caacggggca aagggttata cgcagactac cttttcaacg ctattgccgg gaactgggaa      420

cgtaagcgcc ccgtttgggt gatgcttatg gtgaattcac ttactgagcg ggacgtgcga      480

ttcagagggg tgcccgtact ggatctctac ctggcacagc aggctgagaa gatgaagaag      540

accacaggag cggtcgagca ggtggaggag cagtgccatc ctttgaacaa cggactgaat      600

ttttcccagg tgttgttcgc attgaatcag accttattac aacaggaatc tgtccgggcc      660

gggtctttgc aggccagtta caccactgaa gatctcatca aacactataa ctgcggagac      720

ctgagtgcag tgattttcaa ccacgacacc tcccagctgc ctaacttcat caacaccacc      780

ctgccacccc atgagcaggt cactgctcag gagatcgaca gctattttcg tcaagaactt      840

atctataaac ggaacgaacg aatgggcaag cgcgtcatgg cgctgctgcg tgagaatgaa      900

gacaagatct gcttcttcgc ctttggcgcc ggtcacttcc tgggtaacaa caccgtgatt      960

gacatactga ggcaggccgg attagaggtg gatcacactc cggccggaca ggccatacat     1020

tcccccgctc cccagtcccc tgccccttca cctgagggga ccagcacctc tccagcccca     1080

gttactcccg ccgcagctgt cccagaggct ccttctgtga ccccaaccgc accccccgaa     1140

gacgaggacc ccgccctgtc accacatctt ctgcttccgg attcactgag ccagctcgag     1200

gagttcggaa gacagcgaaa atggcataaa aggcagtcta cacatcagcg tccacgacag     1260

ttcaacgact tgtgggtgcg gatcgaagat tcaaccaccg cgtccccccc gcctctgccc     1320

ctgcagccga cccactcttc aggaaccgct aagcctcctt tccaattgtc cgaccagttg     1380

cagcagcagg acccacctgg gcccgccagc agttctgccc ccacc                     1425


<210>  4830
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  4830
atgcctctcc gtgacgagac ccttagagag gtgtgggcta gtgactccgg gcacgaggaa       60

gagagcctga gccctgaggc cccccgcagg ccaaaacagc ggccagcccc agctcagcgc      120

ctgaggaaga agagaaccga agctcctgaa tctccctgcc cgaccggcag caagcctagg      180

aagcccgggg caggtagaac aggtaggcca cgcgaggaac ccagtccaga tccagcacag      240

gcccgtgccc cacagactgt ctacgccagg tttctgagag accccgaggc caaaaaaagg      300

gacccacgcg agaccttcct ggttgctcgc gccccggatg ccgaggacga ggaggaggaa      360

gaagaggaag atgaggaaga tgaagaggaa gaagctgagg agaagaagga gaagatcctc      420

ctgcctccca agaagcccct cagggagaaa agcagcgcag atcttaagga acggcgggcc      480

aaagctcagg gaccacgggg agacctgggc tctcctgacc ccccccctaa accgctgcgt      540

gtaaggaata aagaggctcc tgcaggagag ggaacgaaaa tgcggaaaac taagaagaaa      600

ggcagcggag aagctgacaa ggatcccagt ggttccccag cttctgctag gaagagccca      660

gctgctatgt ttttagtcgg tgaggggtcc cccgacaaga aggccctgaa aaagaagggg      720

actccaaaag gggcacggaa ggaggaggag gaagaagaag aggccgcgac agtgatcaag      780

aaatctaacc agaagggtaa ggccaaagga aaggggaaga aaaaagccaa agaggaaaga      840

gcacccagtc cacctgtgga agtagacgaa ccccgggaat ttgtgcttcg gccggctcct      900

cagggtagaa ctgtccgatg tagactgacc agagacaaga aggggatgga tcggggaatg      960

tatccctctt actttctgca cctggacacc gaaaagaaag tgtttctctt agccggcaga     1020

aaaagaaagc gctccaaaac ggccaattat ctgatctcta tagatcctac aaacttatct     1080

agaggcggcg agaactttat cggcaaatta agaagcaatc tgcttggcaa ccgattcacc     1140

gtgttcgata acgggcagaa cccacagcgc ggctatagca caaacgtggc gagtttgaga     1200

caagagctgg cggctgtgat ctatgaaact aacgtgctcg gcttcagagg acctcggcgg     1260

atgactgtaa tcattcctgg gatgtctgca gaaaatgaaa gagtgccaat tcggccgagg     1320

aacgcgtctg atggactgct ggtgaggtgg caaaataaga ctctggaatc actcattgag     1380

ctgcacaaca agccacctgt ttggaacgat gattcaggct catacactct gaatttccag     1440

ggaagagtga ctcaggctag cgtgaaaaac tttcagatcg tacatgccga tgacccagac     1500

tatattgtcc ttcagtttgg acgcgttgct gaggatgcct tcaccctgga ttatcgatat     1560

ccactttgcg ccttacaggc cttcgcaatt gccttgagtt ccttcgacgg caagctggca     1620

tgcgag                                                                1626


<210>  4831
<211>  1326
<212>  DNA
<213>  Homo Sapiens

<400>  4831
atggaagcct ccaggtgtcg tctgtctccc agcggagact ctgtatttca tgaagagatg       60

atgaaaatgc ggcaggcaaa attggactat cagagactgc tcctggagaa gcgtcagaga      120

aaaaaacgtt tggaaccttt catggtccag cctaatcccg aggcccgtct gcgccgtgct      180

aaaccccgtg ctagtgatga acagacccca ctcgtgaact gtcatacccc tcactctaat      240

gtaatcttgc acggaataga tgggccagca gcagtgctga agcctgacga agtccacgca      300

ccgagcgtct cctcctcagt tgtggaagaa gatgctgaaa acacagtgga caccgcaagt      360

aaaccaggat tacaagagag actccaaaaa cacgacatct ccgagagtgt taatttcgac      420

gaggagactg acggcatatc ccagtcagca tgtctcgagc ggccaaactc tgcttcttca      480

cagaattcaa cagacacggg aaccagtggg agcgcaaccg ccgctcaacc ggcggataac      540

cttcttggtg acattgacga cctggaagat tttgtgtact ctccggctcc gcagggagta      600

accgtaaggt gcaggatcat tcgggataaa aggggaatgg accgggggct ctttccaaca      660

tactatatgt atctggagaa ggaggagaac cagaagatct tcctgctggc tgccaggaag      720

cggaaaaagt ccaagactgc aaattacttg attagcatag accccgtcga tctgtcccgc      780

gagggcgaat cctacgtggg caagctccgt tctaatctga tgggcacgaa atttaccgtg      840

tatgaccggg ggatttgccc aatgaaagga agagggctgg tgggcgccgc ccacactagg      900

caggagctgg ccgctatcag ttacgaaact aatgtgctgg gctttaaggg cccccgcaag      960

atgtctgtta ttatccccgg catgactctg aaccataaac aaattccata ccagccacag     1020

aacaaccatg atagcctgct gagccgttgg cagaacagaa ccatggaaaa tctggtggag     1080

ttgcataaca aagcgcccgt gtggaattcc gatacacagt catatgtgct gaatttccga     1140

ggccgtgtga cccaagccag cgttaaaaac ttccagatcg tccataaaaa cgaccccgac     1200

tatattgtga tgcagttcgg gcgggtggct gatgacgttt tcacgctgga ttataactac     1260

ccactttgtg cggtacaggc attcggaatc ggactgtcat cttttgatag taaactggcg     1320

tgcgaa                                                                1326


<210>  4832
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  4832
gttaagcaaa tagagtctaa gacagcattc caggaggcat tggatgctgc cggagacaaa       60

ctggtcgtgg tcgacttcag cgctacgtgg tgcggaccat gtaagatgat caaaccattc      120

ttccactccc tgtccgagaa gtactccaac gtgatcttcc ttgaggtcga cgtggatgat      180

tgtcaggacg tcgctagcga gtgcgaagtg aaatgtatgc ccacctttca attcttcaaa      240

aagggacaga aggtgggcga gttctcaggc gccaacaagg aaaaactcga ggccacgatt      300

aacgagttgg tc                                                          312


<210>  4833
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  4833
tctccaaaga gcagagacga agtcaatgtg gagaacaggc aaaaactgcg ggtggacgag       60

ctgcggaggg aatactacga agaacagcga aacgaatttg agaattttgt ggaggagcag      120

aacgatgagc aggaggaacg gtctagggaa gccgtggagc agtggcgaca gtggcactac      180

gacggcctgc acccttccta cttgtataat cgccaccaca ca                         222


<210>  4834
<211>  1410
<212>  DNA
<213>  Homo Sapiens

<400>  4834
ggaaatgtgc tgatatggcc catggagggt agtcactggc tgaacgtgaa aataataatc       60

gacgagctta tcaagaaaga acacaacgta accgtgcttg tggcatctgg tgcactcttc      120

attactccta cttccaatcc ctccctcaca tttgaaatct acagggtccc attcggcaaa      180

gaacgtattg agggtgtgat caaagatttc gttttgacct ggctggagaa tcggccatct      240

ccatccacga tctggcggtt ctatcaggag atggctaagg tcatcaaaga tttccacatg      300

gtgtctcagg agatttgtga cggggtgctc aagaatcagc agcttatggc caaattgaag      360

aagagcaaat tcgaggtcct ggtaagcgat ccagtgttcc cctgtggtga catagtcgct      420

cttaaactgg ggataccgtt catgtattct ctccgcttct cacctgcctc taccgtagag      480

aagcactgtg gcaaagttcc ctatccacct tcatatgtgc ctgccgtcct gagcgaactc      540

acagaccaga tgagcttcac tgatagaatc cgaaacttta tcagttatca cctgcaggac      600

tacatgttcg agactctttg gaagtcatgg gactcttatt atagtaaagc tcttggacgc      660

ccaacgacct tatgcgagac catgggaaag gccgaaatct ggctcattcg cacgtactgg      720

gacttcgaat tccctagacc ttatcttcct aatttcgaat tcgtgggggg attacactgc      780

aagcccgcca agcccctgcc taaagagatg gaggagttca tccagagtag tggaaagaat      840

ggagtggtcg tgtttagtct cggcagtatg gtcaagaact tgacagagga gaaggccaat      900

ttgatcgcga gtgctctcgc gcaaattcct cagaaagtgc tgtggcgata caagggaaag      960

aagcctgcca ccctgggcaa caacacacag ctgttcgatt ggattccaca gaacgacttg     1020

ctgggccacc ccaaaaccaa ggccttcatt actcacggtg gcaccaatgg catttatgag     1080

gctatctacc acggcgtccc tatggtgggg gtgcctatgt ttgctgacca acccgataac     1140

attgctcaca tgaaagctaa aggtgccgct gtcgaggtga atcttaacac catgacaagc     1200

gtcgacctcc ttagcgctct ccgaactgtc attaacgagc cctcttataa ggaaaacgcc     1260

atgcggctca gtcggatcca tcatgaccag cccgtgaagc cactggatcg cgctgtgttt     1320

tggatcgagt tcgtgatgcg ccacaagggg gccaagcacc ttcgggtggc cgctcacgac     1380

ttgacctggt tccagtacca ttcactggac                                      1410


<210>  4835
<211>  1404
<212>  DNA
<213>  Homo Sapiens

<400>  4835
aaagtgcttg tgtgggcagc agaatactct ctctggatga atatgaagac tatcctgaaa       60

gagttggtcc aacgtggcca cgaggtcacc gttttggcct catctgccag catccttttc      120

gatcccaatg actcaagcac actcaagctc gaggtctacc ccaccagtct cactaaaaca      180

gagttcgaga acattatcat gcagctggtc aagaggttat cagagataca gaaggacacc      240

ttttggttgc ccttctccca ggaacaggag attttatggg ccataaacga tattattcgg      300

aacttctgca aagacgtcgt ctccaacaag aagttgatga aaaaattaca ggagtcacgc      360

ttcgatatcg tatttgctga cgcctacctg ccatgtgggg agctgctcgc agaacttttc      420

aacatcccat tcgtctattc tcactcattc agccccggct attcctttga gagacattcc      480

gggggattca tctttccccc cagctatgtg cctgtggtga tgagtaagtt atccgaccag      540

atgacgttta tggagcgtgt gaagaatatg ctctatgtct tgtacttcga tttttggttc      600

cagatcttca atatgaagaa gtgggaccag ttctacagcg aggtgttggg acggcccacg      660

accctgagtg agactatgag aaaggcggac atttggctga tgcggaactc ttggaacttt      720

aagttcccac acccgttcct gcccaatgtg gactttgtgg ggggtttgca ctgcaagccg      780

gctaagcccc tgcctaagga gatggaagag ttcgtccagt catccggtga gaacggagtc      840

gtggtgttct cccttggttc tatggtgtct aacatgaccg aagaaagggc aaacgtcatc      900

gcgaccgccc tggcgaaaat cccacagaaa gtgctgtggc gtttcgacgg taacaaaccg      960

gacgcccttg gcctgaatac tcgcctctac aaatggatac cccagaacga tttactgggc     1020

catcctaaaa caagggcatt tattacccat gggggggcaa atgggatcta cgaggccatc     1080

taccacggga ttcccatggt gggtatccca ctgtttttcg accagccgga caatatagcc     1140

cacatgaagg ctaaaggcgc cgcagtgcgt gtggacttca ataccatgtc cagcactgac     1200

cttctgaacg cattgaagac cgtgatcaac gacccaagct acaaagagaa cattatgaag     1260

ctgtctagga ttcaacatga tcaaccagta aagccactgg accgggctgt tttctggatt     1320

gagtttgtga tgcgccacaa gggagccaag cacctcagag tcgctgcaca caacctgaca     1380

tggttccagt atcactccct tgat                                            1404


<210>  4836
<211>  1410
<212>  DNA
<213>  Homo Sapiens

<400>  4836
aaggtgctgg tatggaccgg tgagtactca cattggatga atatgaagac tatcctcaag       60

gagttggttc aacgtggcca cgaggttacc gtcttggcat ctagcgccag tatcctgttt      120

gatccaaatg acgccttcac cctcaaactg gaagtgtatc ccacgagttt gaccaagacc      180

gagttcgaga acatcatcat gcagcaggtg aaacgatgga gcgatataca gaaggactcc      240

ttctggttat atttctccca ggagcaggag atcttatggg aattccacga catcttcagg      300

aatttttgta aggatgttgt ctctaacaag aaagtcatga agaagctgca ggagagtcgg      360

ttcgacatca tttttgcaga tgctttcttt ccctgtggag agctcctggc ggcactgctg      420

aacattccgt ttgtgtattc actctgcttt acacctggtt ataccattga gcgccatagc      480

ggaggactca tcttcccccc ttcctacata cctgtcgtaa tgagtaagct gtcagatcag      540

atgaccttca tggaacgcgt gaaaaatatg atttatgttc tctatttcga cttctggttt      600

cagatgtgtg atatgaagaa atgggaccag ttctatagcg aggtactggg acgtccaaca      660

accctgttcg aaaccatggg caaggctgac atttggttga tgcggaactc ctggagtttc      720

cagtttcccc acccgtttct ccctaacata gatttcgtgg gcggactcca ctgcaaaccc      780

gccaaacccc ttcccaaaga aatggaggag ttcgtgcaaa gcagcggaga gaatggcgtc      840

gtcgtgttct ccctgggatc cgtaatctca aatatgaccg ccgaaagagc caacgtaatc      900

gcgaccgcac tcgctaaaat cccccagaag gtgctgtggc gttttgacgg taataaaccg      960

gacgctcttg ggctcaatac acgtctctac aaatggattc cccagaacga tctgctcgga     1020

cttcctaaaa ctcgcgcctt cattacccac gggggggcta atgggattta tgaggccata     1080

taccatggta tccccatggt gggcattcca ctgttctggg atcagcccga taatatagct     1140

catatgaaag ccaagggcgc cgcggttagg ttggactttc acaccatgtc atcaacagat     1200

ctcctgaacg ccctgaagac tgtcatcaac gaccctagtt ataaggaaaa tgtgatgaaa     1260

ctgagcatca tccagcacga ccagccagtg aaacccctcc accgagccgt attctggatt     1320

gaattcgtga tgtgccacaa aggtgccaaa catctgcgtg tggccgctcg agacctgacg     1380

tggttccagt accactcttt ggacgttatc                                      1410


<210>  4837
<211>  1353
<212>  DNA
<213>  Homo Sapiens

<400>  4837
gccaaaatta ttattgtccc tcccattatg ttcgagagtc acatgtatat atttaaaacc       60

ctcgcttcag ctcttcatga gcggggccat cacactgtat ttctgctctc agagggacgg      120

gacatagcgc cttccaatca ctactcactg cagagatacc caggaatttt taattctacc      180

accagtgatg ccttcttgca gtccaagatg agaaacatat tcagtggcag gcttaccgct      240

attgagttgt ttgatatctt agatcactat acgaagaatt gcgacctgat ggtaggaaat      300

catgctttga tacagggact gaaaaaggaa aaatttgacc tcttactggt ggacccgaat      360

gatatgtgcg ggttcgtgat cgcgcatctg ctgggtgtga agtatgcagt gttcagcaca      420

ggactttggt acccagcgga ggtgggggct cccgctcccc tcgcttatgt ccccgagttc      480

aacagtttac tgaccgatcg gatgaatctc ctgcagcgca tgaaaaacac tggtgtgtat      540

cttatctcaa gactgggcgt gagctttctg gtcctgccga aatacgagcg cattatgcaa      600

aagtacaacc tcttaccaga aaaaagtatg tatgatttgg tgcacgggtc aagtctctgg      660

atgctctgta ccgacgttgc cctcgagttc ccccgaccta ctctgccaaa cgtggtgtac      720

gtgggcggga tattgacgaa accagcaagt ccgctccctg aggatctcca aaggtgggtg      780

aacggtgcta atgaacacgg cttcgttctt gtgtcttttg gtgcgggggt gaaatacctg      840

tctgaggata ttgcgaataa attggcgggc gcgctgggcc ggttgcctca aaaagtgatt      900

tggcgcttct ctggcccaaa acctaagaat ttggggaata atactaagct catcgagtgg      960

cttccacaga acgatttact cggccactct aaaattaaag cattcctgtc ccacggcggg     1020

ctcaacagca tcttcgaaac tatctaccat ggtgtgcctg ttgttggtat ccccttgttc     1080

ggggaccatt acgacaccat gaccagggtg caggccaagg gcatgggtat cctcctcgaa     1140

tggaaaaccg taaccgagaa ggaactgtac gaagccctgg tcaaggtaat aaacaatcca     1200

tcttataggc agcgcgcaca gaagctcagc gagatccaca aggaccagcc cggacatccc     1260

gtgaatagga caatatattg gattgattat atcatcagac ataatggcgc acaccatctt     1320

agggccgccg tccatcagat cagcttctgt cag                                  1353


<210>  4838
<211>  564
<212>  DNA
<213>  Homo Sapiens

<400>  4838
gacgctcata gcctctggta taactttaca ataatccatc tgcctagaca cggacagcaa       60

tggtgcgaag tccagtccca ggtggatcag aagaatttcc tcagttacga ttgcggcagt      120

gacaaggtgc tcagcatggg acatctggag gagcagctgt acgcaacaga tgcttggggt      180

aagcaactcg agatgctcag ggaggttggt cagagattac ggttggaatt agccgacacc      240

gaactggagg atttcacccc aagcggtcca cttaccctgc aggtaaggat gtcctgtgag      300

tgcgaggctg acggttacat ccgcggctca tggcagttta gctttgatgg gcgcaagttt      360

ctgctgttcg attctaataa ccgaaagtgg actgtcgttc acgccggcgc cagaaggatg      420

aaagagaaat gggaaaagga ctccggcctg acaacttttt tcaaaatggt gtccatgagg      480

gattgcaaat catggctgag ggattttctg atgcacagga agaagcgact ggaacctacc      540

gcgcccccca ctatggcacc cggc                                             564


<210>  4839
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  4839
cacgaggcgc acaaaacttc actgagtagc tggaaacacg atcaagattg ggctaatgtc       60

tccaacatga ccttcagcaa tgggaagctg agagttaagg ggatctatta caggaacgcc      120

gatatttgca gcagacaccg cgttaccagc gccggcttga cccttcagga tctgcagctg      180

tggtgtaatc tccgctcagt ggctcggggc caaattccta gtaccctc                   228


<210>  4840
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  4840
atgctggaag aagccgcctc acccaacgag gccgtgcatg cttcaacatc cggtagcggt       60

gcgcttaccg atcaaacctt taccgattta agcgcagcag aggcttccag tgaggaggtc      120

ccagacttta tggaggttcc tcactccgtt catcacaaga tcaactgctt cttttactta      180

gagaagcaac tgtgccaatt gccttcacct ttgtgtcttt cctccctttt gacattgaag      240

ctcaaaacta cggtaccagc gccgggtcgt tggtggtctt ttcagccgca caaagctttt      300

cctctgctgg tgggcacccc cggtagctgg cagagtacta ttgaccctgc ctgggccgct      360

ccttctcagc ctagtcctgg a                                                381


<210>  4841
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  4841
ggaagggatc ccagcgcttc tcgggcccgc ttccctcaga gactcggacg tgcaccgtgt       60

ttcgaagttg ggctgcggaa gcctccacct ccccctcttc tcagtcctcc cagcttcagt      120

tccggctcct caaggcccct tcagcgccct agggggccca aggacggagc tggacgcaag      180

gtctgtgcta aactggtcaa gcgcctcccc ggtgagtccg gcagctgcga agacggacag      240

agcgcgccag ctcagccacc tcgtcgtaga acaggaacaa gagcttgccc gccacgcgcc      300

cccttatggc gg                                                          312


<210>  4842
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  4842
ttcaacgttc ttataccaaa acgggatgaa gatggagacg gtgagggacc aggagatgtg       60

actgcgggcg tgtctagggc cgccggtagc ccaagcggtt gggaggctcc ctgggtgcaa      120

cagcccaggt gttgtcgacg ggctactccg gtatgttgtg ctggtcaggg ccccccacgg      180

tctcttcagc aggggggttc agaggttctc cttgggcagc tgtgttctcc ggaacccgat      240

tggctgccat ctagtgggcc caaggtggca aagcaggtct tccaagtggc tgctgagctt      300

ctccagcatc ccgaacactt tgttccatcc tctgtcccag aagggtgtgt acataaacct      360

ggctcaactt gtgatggctc cctgaaggga cgagcatacc ctagttgcgt cccaaaacga      420

gatcctgagc actcccgaga agagtcacac cctcttagtg gc                         462


<210>  4843
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  4843
cagcccttac ccgggaacac caccgaggcg acgcccagga gtctccgggc tagcggaagc       60

ctctgtggcc cacacgccaa ggcaccatac ctctgtgagg ctacacacga gccagcagcc      120

gcgcggatac gggcacaggt gccagatacc cgatggagcc gcgtcggagg acagcggttt      180

tactcaagag tattgagccc gctgcatagg ggccccagtg gtcacacaga agcatccgca      240

caaaggagtc atatggggaa gctcaaagaa ccacaacccc aggaccacaa acctggcctg      300

ggtgcgtcc                                                              309


<210>  4844
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  4844
ctgcccttac cctcatacct gcaccacacc attaacttga ctcatagtct gcccgcagct       60

tctaatccta gtctggccaa caattgttgg ttgtgcatta gcctgtcctc cagcgcatac      120

atcgctgtcc caactctgca gacagatcgg gcaacgtctc ctgtcagtct gcacctccgt      180

accagcttca attctcccca cttatatcca ccagaggaac tgatttattt ccttgataga      240

agcagcaaga cctcccctga catttcccac caaccggccg ccgcacttct tcatatctat      300

ctcaagaatc tgagcccata tatcaacagc acccccccaa tctttgggcc tctgaccacc      360

caaactacca tccctgtggc agccccactc tgcatctctc gacagcggcc tacagggatc      420

cctttgggga atatctcccc ctcccgatgc tcctttacac tccaccttca gagccccacc      480

actcacgtca cagagacaat aggggtgttt cagcttcaca tcattgataa gccctctatc      540

aacactgata agctgaagaa tgtgtcatcc aactattgtc tggggcgcca tttgccttat      600

atttccctcc acccttggct cccgagtccc tgcagtagtg actccccgcc tagacctagt      660

tcctgcttac tcacccccag tccacagaac aactcagaaa ggttactggt cgacactcaa      720

aggttcctga tccaccacga aaatcggacc tctagctcta tgcagttagc acaccaatct      780

cctcttcaac cccttacagc agcggcactg gcgggatctc tcggggtgtg ggtgcaagac      840

acccctttta gcactccatc ccatccattt tccctgcatc ttcaattctg tctgacccaa      900

gggttatttt tcctgtgtgg atcctcaaca tatatgtgct taccagctaa ctggaccggc      960

acctgcaccc ttgtgttcct cacacccaag atacagtttg caaacggaac caaggaactc     1020

cctgttcctt taatgacact gacaccccag aagcgc                               1056


<210>  4845
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  4845
ctgccattac cctcttattt gcaccatact ataaacctta cacatagtct gctggccgcc       60

tctaatcctt ctctggtcaa caactgttgg ctgtgcatta gtctgagctc ctctgcgtac      120

accgccgtcc cggctgtgca aaccgactgg gccactagcc ctatcagtct tcacctgagg      180

acaagcttta acagtcctca cttgtatcca cccgaggagc tcatctactt cttggacaga      240

tccagcaaga ctagcccaga tatcagtcac cagcaggccg ccgccctcct ccgcacctac      300

ttgaagaatc tctcaccgta tattaatagc acaccaccta ttttcgggcc cctgacaacc      360

cagacaacca tcccagtagc cgcccctctc tgtatctcct ggcaacggcc aacagggatt      420

ccgctcggca acctgagccc ttcccgttgt agttttactc tccatttgag gagtcccact      480

acgaacatca acgagacaat cggtgcgttt caattacaca tcactgacaa gcccagtata      540

aacaccgaca agctcaagaa catctcttca aattactgcc ttggcagaca cctgccctgt      600

atttccctcc atccctggct ttcttcccca tgcagcagtg acagtccacc taggccctcc      660

tcctgtctct taatcccaag ccccgagaac aatagcgaaa gattgctggt tgataccaga      720

cgcttcctga tccatcacga gaatcggaca ttcccttcaa ctcaattgcc tcatcagtcc      780

ccacttcagc ctctgaccgc cgccgcactt gccggaagcc tgggggtctg ggtccaggac      840

actccgtttt caaccccgtc acatctcttt actctgcacc tgcagttctg cctggctcaa      900

gggctgttct ttctctgcgg atcctctaca tatatgtgcc tgccagctaa ttggaccggg      960

acatgtacac tggtctttct cactcccaag attcagttcg cgaacggcac agaagaactg     1020

ccagtgccac tcatgacccc gacacagcag aagaga                               1056


<210>  4846
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  4846
acatttttgc ctgtgttagc tgccacggag cccgccgtga gcgtgccaag cggcgacttg       60

agtatgccag taaaaactag ggcagaagga gaagatgatg gattcggcga agccggtgat      120

ccaagaaggc ttctggagcg gccctggaga ttccgcggtt gtctgcccgg taagggaaac      180

cgagatgtgg gcttcgaagg gactgagggc ccgactagta ccagacccga gtgggtatgg      240

tcttgccgtt gctgtctcgg ctgcagagcc tctacacggg aacgggtgac ctccccggtt      300

agggccgccg gccctcagcc aagattcact gatcgcgaga cggaggcggc cgcaggcaca      360

ctggcccata tgggcttcgc gccgcccact tccttcagcc atttcaccga ccaggagttg      420

agggattgta gcagcctgga gtgtttgggt gtcgtggaag gtgaccccca tgtgttatgc      480

tccactctgt cattgagtag gccctcacct tcagcaacgc ttacc                      525


<210>  4847
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  4847
agagtgggca cctacgccgt gtgttggtgt tcttggaata ccggccgttt tactgggtgc       60

ccatcctgga aagacttctg gaaaccagtc ggcccggccc tgcatgtgtt taacgtcaag      120

tgcgaggctc aacgcggcct caagctgaca cagcccttta cagtcgcctg taagatcgac      180

ccggtgctgt gtaagtctgg ccttggtttt cctccccaac tgtttactgg atgtgtttac      240

ctgagcactt atacctatcc atggcaggca caagctgagt gtgtgagatg tcctcgtgat      300

tcaaatcgct gtaaaagaat tacgccgtct gcttgtctc                             339


<210>  4848
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  4848
gtgaactttt acctgccgcc agagtctatt gacttcgaat tcatggctca caattggtcc       60

aaggggcgct ccccaagttc cacactcgga ctgagttggt tcaaggccgg gtttagattc      120

agtgacggct ggtctatgtt ctattcatcc ggacttccag gtgttgccct gccggggagc      180

cctccacggt cccatctgct ccctggtacc cagatcctga tacgctcttt tcagccttgc      240

gagagcgcca agcattccgc acgcctttca tcattactta caacaacgtc ttacagcgtg      300

tct                                                                    303


<210>  4849
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  4849
gtgaattttt acctgccacc cgagagcatt gacttcgagt tcatggccca caactggagc       60

aaagggcggt ccccatcaag cacgctcgga ctgtcatggt tcaaggctgg atttcggttt      120

agcgatggct ggtctatgtt ctattctttt ggcttacctg gggtggctct tcccggctct      180

ccaccccgca gtcacctcct gcccgggact cagatcttga tccgttcttt ccaaccatgc      240

gagagcgcaa aacatagtgc ccgcctgagc tcactcctta ccacgacctc ttattcagtc      300

agc                                                                    303


<210>  4850
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4850
gccgagcatc tgccacacag gcctgctgtg gagaaggatg tccctggagc cggggaggtt       60

ctgtttatgt gctcatggcg gattttcccc gtggcctccg cctctccgtc ttctagcatt      120

tcagggctgg ccggtcacag cgtgtttctg gtgcctggcc tcgccgccca tccaggctca      180

catagtgatc agccacccgg cgtaccttct cggcggaaaa gcagacttga gaggtggtcc      240

ccttctgtta gtcgctctac ctccccccca actgaggccc cattttgcct c               291


<210>  4851
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  4851
gcttgtgtcg tggtctccag agattggctt tcattggtgc ctgccttctt ttacagcccg       60

ccacctggag ggagcttttc cgggatcaaa cgcgagagcc gtcgcaagcg accatccagg      120

aatgagattt atgggggcgg agtccttgag caggaggtta ggatgcgacg gtggagtaag      180

accgcatcac cacctgtttc cctgcatcac cggcccctcg gccctgcccg gaagcct         237


<210>  4852
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  4852
ggcaccgatg tcgcagcacc tgagcatatt tcatacgtgc cgcaactgtc taacgacaca       60

ttggctggga gattaaccct gtccactttc acactggagc aacccttagg tcaatttagt      120

tctcacaata tcagcgacct tgataccata tggctggtgg tggccctcag taatgccacc      180

cagagcttca ctgcacccag aaccaatcaa gacattcccg caccagcgaa ctttagccaa      240

cggggatact atttgacact gcgcgcaaat agagtccttt accagacacg tggccagctc      300

catgtcctcc gcgttggaaa cgatacgcat tgtcagccaa caaagatcgg gtgtaatcac      360

ccccttccag gacctggacc atacagggtg aagttcctgg ttatgaacga tgagggccct      420

gtggcggaaa caaaatggtc cagcgatacc cgattgcagc aagcacaggc ccttcgcgcc      480

gtcccaggtc cacaaagccc tggcaccgtg gtg                                   513


<210>  4853
<211>  1065
<212>  DNA
<213>  Homo Sapiens

<400>  4853
atgacaggct ccgcggctga cacccaccgt tgtcctcatc caaagggggc taagggtacc       60

cgcagcagga gcagccatgc cagaccagtt tctttagcta cgagcggggg gagcgaagaa      120

gaagataaag atggcggcgt tctttttcat gtgaacaaat cagggttccc tatcgattcc      180

catacctggg agaggatgtg gatgcacgtg gctaaagtgc acccaaaagg cggagagatg      240

gtgggagcaa tccgaaatgc agccttcctg gccaagccaa gcatccctca agttccaaat      300

tataggctct ccatgactat acctgactgg cttcaagcaa tccagaacta tatgaaaacc      360

ttacagtaca accatactgg cacacagttc tttgagatca ggaagatgag acccctttcc      420

ggactgatgg agacagctaa agaaatgaca agggagtcac tcccgatcaa gtgcttggag      480

gcagtgatcc ttggcatcta cttgactaat gggcagccta gcatagaaag gttcccaata      540

agtttcaaaa cctatttctc cggcaactac tttcaccatg tggtcctcgg tatctactgc      600

aatggaaggt acgggagcct cggcatgtct cgtcgggcag agttaatgga taaacctctc      660

acgtttagga cgctgtctga cttgatcttc gacttcgaag atagctataa aaagtatctg      720

cacaccgtca agaaagtcaa gataggactg tacgtccccc acgagcctca cagcttccag      780

cccatcgaat ggaagcagct ggtgctcaac gtgtctaaga tgttgagggc ggatatccga      840

aaagagttag aaaaatatgc cagagatatg cggatgaaga tcttgaaacc tgcctcagca      900

cattctccga ctcaggtacg aagtcgcggc aagtcccttt caccccgtag acgccaagcg      960

agtccgccta ggcgactcgg tcgccgggag aagagtcccg ctctgccaga gaaaaaggtg     1020

gcagacttat ctactctgaa tgaggttggt taccagatca gaatc                     1065


<210>  4854
<211>  1344
<212>  DNA
<213>  Homo Sapiens

<400>  4854
ctcgacacct tcatcgcagc cgtctatgag cacgccgtga ttctccccaa ccgcacggaa       60

acccctgttt caaaggaaga agctttgctg ctgatgaaca aaaacataga tgttctcgag      120

aaagctgtta agttagccgc aaagcaagga gcacacatta tcgtgacccc cgaagatggg      180

atctacggat ggatattcac ccgggaaagc atctaccctt atttagaaga cattccagac      240

cccggggtaa actggatccc ttgccgggac ccctggaggt tcgggaatac gcccgtgcag      300

cagcgtttat cctgcttggc caaggataac tccatctatg tggtcgccaa tatcggcgac      360

aagaagcctt gtaacgccag cgactctcag tgccctcctg atggccgcta ccaatacaac      420

actgatgtgg tctttgatag ccaaggaaaa ctgctggccc gctatcataa atataatctg      480

ttcgcacctg aaattcagtt cgattttcca aaggactcag agttggtaac gtttgacacg      540

cccttcggca aatttggcat ctttacatgc tttgatatct tttctcatga cccggcggtg      600

gtggttgtgg acgaggtgag cattgactcc attttatatc ccaccgcctg gtataatacc      660

ttgcctctcc tcagcgctgt ccccttccat agtgcgtggg caaaggccat gggcgtaaat      720

cttttggctg cgaataccca caacaccagt atgcatatga ccgggtctgg gatctatgcc      780

cctgaagctg ttaaagttta ccactatgat atggaaactg aatcaggtca gctgctgctg      840

agcgaactta aatcacgccc ccgacgcgag ccaacttacc cagccgctgt tgattggcac      900

gcctacgcgt catccgtgaa acccttttct tctgaacaaa gtgacttcct gggaatgatt      960

tatttcgacg aatttacttt tactaagtta aagcgtaata caggcaacta tacagcctgt     1020

caaaaagacc tctgttgcca cctgacgtac aagatgtcag aaaaacggac tgacgagata     1080

tatgctctgg gagcattcga cggcctccat actgtggagg gccagtacta ccttcagatc     1140

tgtgcactgc tcaaatgcca gaccaccgac cttgagacct gcggggagcc tgtgggctct     1200

gcctttacaa agttcgaaga cttttccctg agcggtactt tcggtactag atatgtgttt     1260

ccacagatta tcctttccgg tagccagctg gctccagaac gacattacga gatcagcaga     1320

gacgggcgcc ttcggtcaag atcc                                            1344


<210>  4855
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  4855
agtcccaagc agcgcgtcct taagtatatt ctggaaccgc ctccatgcat aagcgcccct       60

gaaaattgca cccatctttg tactatgcag gaagactgtg agaagggatt ccagtgttgt      120

tcctcctttt gtggaattgt ttgtagctca gaaactttcc agaaaagaaa ccgcatcaag      180

cacaagggta gtgaagtgat tatgcccgcg aac                                   213


<210>  4856
<211>  609
<212>  DNA
<213>  Homo Sapiens

<400>  4856
atgctcacca aaaagattaa gcataaacct gggctgtgcc cgaaggaaag gctcacttgc       60

accacagagc ttcccgattc ctgcaatacc gattttgact gcaaagagta tcagaaatgc      120

tgtttcttcg cttgtcaaaa gaagtgtatg gatccattcc aagagccttg catgctgcca      180

gtccgtcacg gaaattgcaa ccatgaagct caacgttggc atttcgactt taagaactac      240

cggtgtactc ctttcaagta tcgaggatgc gagggcaatg ccaacaactt tcttaacgaa      300

gacgcctgtc gcaccgcatg tatgctgatt gtgaaagatg gtcagtgccc cttgttcccc      360

ttcacggaga gaaaagaatg tccaccaagc tgccacagtg acatcgattg cccacagacc      420

gataagtgtt gcgaaagtcg ttgcggtttt gtctgcgcac gtgcttggac tgtgaaaaag      480

gggttttgcc cacgcaagcc acttctttgt accaagatcg ataagccaaa atgtctgcag      540

gacgaagagt gcccactcgt ggagaagtgc tgctcacatt gcggactcaa gtgcatggac      600

cctaggcgg                                                              609


<210>  4857
<211>  1035
<212>  DNA
<213>  Homo Sapiens

<400>  4857
accgcactgt caccagcccc taccaccatg gactttaccc ctgcacccct cgaagatacc       60

tcctcacgcc ctcagttttg taagtggccc tgtgaatgcc ccccttctcc ccctcggtgt      120

cctttgggag tgagtctgat tacagacggg tgtgaatgct gtaaaatgtg cgcacagcag      180

ctgggggaca actgcaccga agctgctatt tgtgatcccc acaggggcct ctactgcgat      240

tacagtgggg acagaccccg ttacgctatc ggcgtgtgcg ctcaggtagt aggtgttggg      300

tgtgtgctgg atggagtgag gtataataat ggccagtcct ttcagcccaa ttgtaagtac      360

aactgcacct gcatcgacgg cgctgtcgga tgtactccgc tctgcttgcg ggtgcgccca      420

cctcggcttt ggtgccccca ccctcgaagg gtatctatcc ctggtcattg ttgtgaacaa      480

tgggtctgcg aggatgacgc aaagcggcca cgaaaaactg cacccaggga taccggtgct      540

ttcgatgctg tcggagaagt cgaggcctgg catagaaact gcattgctta cacatcccca      600

tggagcccct gcagcacttc ctgcggctta ggtgtgagca cacggatctc caacgtcaac      660

gcacaatgct ggcccgagca ggaaagccgg ctctgtaatt taagaccctg cgacgtagat      720

atccatacct taataaaagc aggtaaaaag tgcctggccg tgtatcagcc cgaggcatct      780

atgaatttca ctctcgctgg ctgtatttcc acgagaagct accagccaaa atactgcggc      840

gtatgtatgg ataatcgttg ctgtatccct tacaagtcca agactattga cgtgagcttc      900

cagtgcccag acggactggg atttagccgc caggttctct ggattaatgc atgtttctgt      960

aacctgtcct gtcgcaatcc taacgacata tttgccgatc tggagagcta ccctgacttc     1020

tctgagatcg ccaac                                                      1035


<210>  4858
<211>  1002
<212>  DNA
<213>  Homo Sapiens

<400>  4858
ggctacccaa tatggtggtc tttagctctt gggcagcagt acacctcact gggatctcaa       60

cctcttcttt gcggcagtat tcccggactg gtccccaaac aactgagatt ctgtcgcaac      120

tacattgaga ttatgccatc cgtggcggaa ggagtgaaac tgggcatcca ggagtgtcaa      180

caccagttcc gcgggcggcg gtggaattgt acgaccattg acgattctct ggccatcttc      240

ggaccagtct tggacaaggc tactagagag tccgcatttg tccacgccat cgccagtgca      300

ggcgtcgctt tcgccgtcac acgctcatgt gcagagggaa cctctaccat ttgtggatgt      360

gattctcacc acaagggacc gccgggcgaa ggatggaaat ggggcggctg ctcagaggat      420

gcagacttcg gcgtccttgt cagcagggag ttcgcagacg ctagagagaa ccgtccagat      480

gccagatccg ccatgaacaa acacaacaat gaagctggga ggacaactat attggaccat      540

atgcacctta aatgcaaatg tcacggactg agtggaagct gtgaagtgaa aacatgttgg      600

tgggcacagc ctgattttcg ggcgatagga gacttcctta aggacaagta cgattctgcc      660

tcagagatgg tcgttgagaa gcaccgtgag tcaagaggct gggtggagac tctgcgggcc      720

aaatacagtt tattcaagcc gccaaccgaa agggacctgg tgtactatga gaattcacct      780

aacttttgtg agccaaaccc cgagacaggc tcttttggaa ccagagaccg gacatgtaat      840

gtgacttccc acgggattga cgggtgtgac ctgctctgtt gcggaagggg acataacact      900

agaacagaga agaggaaaga gaaatgtcat tgcatttttc attggtgttg ttatgtgagt      960

tgccaggagt gcattagaat ctatgatgtg catacctgta ag                        1002


<210>  4859
<211>  1023
<212>  DNA
<213>  Homo Sapiens

<400>  4859
ttgtggtggg ccgtcggatc tccccttgtc atggacccaa cgtctatctg tagaaaagcc       60

agaaggctgg ccgggcgaca ggcagagctg tgccaggcgg agccagaggt ggtggccgag      120

ttagcacgag gggcgaggtt aggtgtcaga gagtgtcagt ttcagttccg gtttaggagg      180

tggaactgct cctcacacag caaggccttt ggccggattc ttcagcagga tattcgagaa      240

acagcctttg tcttcgccat taccgctgca ggcgcttctc atgccgtcac tcaggcatgt      300

agcatggggg agctgctcca gtgcggatgt caggccccca gagggcgggc gcctccgcgc      360

cccagtggct tgccggggac cccaggtcct ccaggccctg caggtagccc tgagggcagc      420

gccgcttggg agtggggggg atgtggggat gacgtggatt ttggcgacga aaagagtaga      480

ctgtttatgg atgcccgaca caaacgagga cggggagaca tccgtgccct ggtgcaatta      540

cataacaacg aagccggcag actggccgtt cggtcccata cccggaccga gtgcaagtgt      600

cacggcttat ctggtagctg cgccctgaga acatgctggc agaagctgcc cccgttcaga      660

gaagtgggcg ctagactgct ggagaggttt cacggggcga gtagggtgat gggcacgaat      720

gacggaaaag ccctcctgcc tgcagtaaga actctcaaac ctccaggacg agcggacctg      780

ttgtacgccg cagactcccc tgatttttgc gccccgaatc gtaggactgg gtcccctggg      840

accagggggc gggcatgtaa tagcagcgct cccgacctct cagggtgtga cttgttgtgc      900

tgcgggcggg gacaccgcca ggagtcagtg cagctggagg aaaactgcct ctgccgcttt      960

cactggtgct gcgtcgttca atgtcacagg tgtcgcgtgc gtaaggaact gagtctgtgt     1020

ctc                                                                   1023


<210>  4860
<211>  981
<212>  DNA
<213>  Homo Sapiens

<400>  4860
gtaaacaatt tcttgatcac cgggcctaaa gcatatctca catatactac ctccgtggcg       60

cttggggctc agtccggaat tgaagagtgt aaattccagt ttgcctggga aaggtggaac      120

tgccctgaaa acgcccttca gctgtctaca cataatcgcc ttaggagcgc cactcgtgag      180

acatcattta tccacgctat ctcctccgca ggggtcatgt atatcattac caagaattgc      240

tcaatgggcg acttcgagaa ctgcgggtgt gacggctcta ataatgggaa gactggcggt      300

cacgggtgga tttggggggg gtgttctgat aacgtcgagt tcggcgagcg catttctaag      360

ctttttgtgg actccctgga gaaggggaag gacgcgcggg cactgatgaa tttgcataat      420

aatagagctg ggaggctggc tgtccgagct acaatgaagc ggacatgcaa atgtcacggc      480

atctccggat cttgcagcat ccaaacctgc tggcttcagt tggccgagtt tagagaaatg      540

ggtgactacc tcaaagctaa atacgaccag gcacttaaga tcgagatgga taagagacaa      600

ttaagagccg ggaatagtgc tgagggtcat tgggtaccag cagaggcttt tctgccctcc      660

gctgaggccg agctgatttt cctcgaggag tccccggatt actgcacttg taattcatct      720

ctggggattt atgggacaga gggacgggaa tgcttgcaaa actcccataa cacttcccgg      780

tgggagcgcc gctcatgtgg ccggctctgc actgaatgtg gacttcaggt ggaggagcgt      840

aaaacggaag ttatctcctc ttgcaattgt aagttccagt ggtgctgtac tgtgaaatgc      900

gaccagtgca ggcatgtggt ctctaagtac tactgcgcgc ggagccccgg gtccgcacaa      960

agcctgggga agggcagtgc c                                                981


<210>  4861
<211>  1005
<212>  DNA
<213>  Homo Sapiens

<400>  4861
agctatttcg ggctgactgg gcgcgaggtc ctgacaccct tccctggcct gggaaccgcc       60

gccgcgcccg ctcagggtgg tgcccacttg aaacagtgcg atctgcttaa gctgtctagg      120

cgtcaaaaac agttatgtcg gcgcgagccc ggcttggccg agacgctgcg agacgcagcc      180

cacctgggcc tgttagaatg ccagtttcaa tttcggcatg aaaggtggaa ctgtagttta      240

gaaggaagga tgggtctgct caagagaggc ttcaaagaaa ccgcttttct gtacgcagtg      300

tccagcgcag ccctgaccca tacactggct agggcgtgca gcgccgggag gatggagaga      360

tgcacatgcg atgactcccc cggcttagaa tcacgacagg catggcagtg gggcgtgtgt      420

ggcgataatt tgaagtattc aaccaagttc ctgtcaaatt ttctcgggtc aaagcgtgga      480

aacaaagact tgcgcgccag ggcggacgcc cataacaccc atgttgggat taaagctgtt      540

aagtcaggac ttagaacaac ctgtaaatgt catggcgtgt ccggcagttg cgcagtgaga      600

acctgctgga aacagctgag tccctttagg gagaccggac aagttctgaa actgcgctat      660

gatagtgcgg ttaaggtgag ttccgccact aacgaggctc ttggcagact ggagctgtgg      720

gcgccagcaa ggcaaggctc acttacgaaa ggccttgctc ctaggtcagg tgatctggtc      780

tacatggaag acagcccctc attctgccgt cctagcaagt actcacccgg aaccgctggt      840

cgtgtctgtt ctcgggaggc cagctgctcc tccctgtgct gcggtcgggg gtatgatacc      900

caaagcaggc tcgttgcctt cagttgtcac tgccaggtgc agtggtgttg ttacgtcgag      960

tgtcaacaat gtgttcagga agagctggtg tacacctgca agcac                     1005


<210>  4862
<211>  1095
<212>  DNA
<213>  Homo Sapiens

<400>  4862
cagcctttgt ggcttctcca gggaggcgcc tctcaccctg aaacaagcgt gcagccagta       60

ttggtagagt gccaggaggc taccctgatg gttatggtgt ctaaggactt gttcgggaca      120

ggaaaactga tcagggctgc tgacctcaca cttggcccgg aggcatgtga gccgctggtt      180

tccatggaca cagaggatgt ggtccggttt gaggttggcc tgcacgaatg cggcaacagt      240

atgcaggtga cagacgatgc cttggtctac agcacttttc tgctgcatga cccgcgccca      300

gtggggaact tatccatcgt gcgtactaac agggccgaaa tccctatcga atgccggtat      360

cccagacagg gaaacgtctc ttctcaggcc atcctgccga cctggctgcc cttcaggacc      420

accgtgtttt ctgaggagaa gttgactttc tctctgcgac tgatggagga gaattggaac      480

gccgaaaaac gctctccaac tttccacctc ggggatgctg cgcacctgca agctgagatc      540

cataccggca gccatgtgcc actgcggctg tttgtggacc actgcgtcgc tacgccaact      600

cctgaccaga acgcgtcccc ttatcatacg attgtcgact ttcacggatg tttagttgac      660

ggacttacgg acgcctcctc cgcgttcaag gtgccccgtc caggcccaga cactctccag      720

tttaccgtcg acgttttcca ctttgctaac gacagccgga atatgattta catcacttgc      780

cacttgaagg ttactttggc ggaacaggat ccagacgagc ttaacaaggc gtgtagcttc      840

agtaagccta gtaatagctg gttcccagtg gaaggctctg ctgatatttg tcagtgctgt      900

aataaggggg attgtggaac ccctagccat tcccgacgac agcctcatgt gatgtcccag      960

tggtcacgca gcgctagccg gaaccgcaga catgtgacag aggaagcgga tgtgaccgtc     1020

ggaccattga tttttctgga ccgcagaggg gaccacgaag tcgagcagtg ggcgcttccc     1080

tcagatacta gtgtg                                                      1095


<210>  4863
<211>  1461
<212>  DNA
<213>  Homo Sapiens

<400>  4863
ggccaacata agcccgaagc gccagactac tcttctgtgc tgcactgtgg cccatggagt       60

tttcaatttg ctgtcaatct caatcaggag gccaccagcc ccccagtgct gatagcctgg      120

gataatcagg gtctgcttca tgagctgcag aacgatagtg actgcgggac ttggatccgc      180

aagggcccag gcagttctgt ggtacttgaa gcaacttaca gcagctgcta tgtcactgaa      240

tgggactccc attacataat gccagtgggg gtggagggag ctggcgctgc cgagcacaaa      300

gtggtcactg aaaggaagtt actgaagtgt cccatggacc tgctggctag ggatgcacct      360

gatacagact ggtgtgactc aatccctgct cgcgacagac tcccatgcgc acccagcccc      420

attagtcgcg gggactgtga agggttaggt tgttgctata gttctgagga ggtcaactcc      480

tgctactacg gtaataccgt cacactgcac tgcacaaggg aaggacactt tagtattgct      540

gtgagccgga atgtgacctc tccgcccctt cttctcgact ccgttagact ggccctcagg      600

aacgactcag catgcaaccc cgttatggcc actcaagcat tcgtgctctt ccaattccca      660

tttacatcct gcggtaccac tagacagatt accggggacc gcgctgtgta cgaaaacgag      720

ttagttgcca caagagacgt caagaatggg agccggggct ccgtgacacg tgattcaatc      780

ttccgactgc acgtgagctg ctcctactct gtcagcagca atagcctgcc gatcaacgta      840

caggttttta cgctgccccc gccatttccg gaaacccagc ctgggccact gaccttagag      900

ctgcagatag caaaggacaa aaattatggg tcttactacg gggtcggaga ctatcccgtt      960

gtgaaactgc tgagggaccc gatatacgtc gaggtgtcta tcctccaccg cactgatcct     1020

tacttggggc tgttactgca gcagtgctgg gccactcctt caaccgaccc actctctcaa     1080

ccacagtggc caatcctcgt aaaaggttgt ccttacatcg gggataatta tcagacccag     1140

ttgatccctg tgcagaaggc attggacctg ccttttccat cacaccatca gaggttctca     1200

attttcacgt tttccttcgt gaacccaacc gtggaaaagc aggccctccg gggccccgtc     1260

catttgcact gctccgtctc tgtgtgccag ccagcagaaa cccccagttg cgtggtgaca     1320

tgtcccgatc tgagccgccg gagaaatttc gacaatagct cacagaatac cacggcctca     1380

gtctcctcca agggccctat gattctgtta caggcaacca aagatccgcc agaaaaactg     1440

agggtgccag tggattccaa g                                               1461


<210>  4864
<211>  801
<212>  DNA
<213>  Homo Sapiens

<400>  4864
atcctgggcg gcgtccctgc gcccgagagg aagtggccgt ggcaggtcag cgtgcactac       60

gcaggcctcc acgtctgcgg cggctccatc ctcaatgagt actgggtgct gtcagctgcg      120

cactgctttc acagggacaa gaatatcaaa atctatgaca tgtacgtagg cctcgtaaac      180

ctcagggtgg acggcaacca cacccagtgg tatgaggtga acagggtgat cctgcacccc      240

acatatgaga tgtaccaccc catcggaggt gacgtggccc tggtgcagct gaagacccgc      300

attgtgtttt ctgagtccgt gctcccggtt tgccttgcaa ctccagaagt gaaccttacc      360

agtgccaatt gctgggctac gggatgggga ctagtctcaa aacaaggtga gacctcagac      420

gagctgcagg aggtgcagct cccgctgatc ctggagccct ggtgccacct gctctacgga      480

cacatgtcct acatcatgcc cgacatgctg tgtgctgggg acatcctgaa tgctaagacc      540

gtgtgtgagg gcgactccgg gggcccactt gtctgtgaat tcaaccgcag ctggttgcag      600

attggaattg tgagctgggg ccgaggctgc tccaaccctc tgtaccctgg agtgtatgcc      660

agtgtttcct atttctcaaa atggatatgt gataacatag aaatcacgcc cactcctgct      720

cagccagccc ctgctctctc tccagctctg gggcccactc tcagcgtcct aatggccatg      780

ctggctggct ggtcagtgct g                                                801


<210>  4865
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  4865
tcactttctc caacaaaata caaccttttg gagctcaagg agtcttgcat ccggaaccag       60

gactgcgaga ctggctgctg ccaacgtgct ccagacaatt gcgagtcgca ctgcgcggag      120

aaggggtccg agggcagtct gtgtcaaacg caggtgttct ttggccaata tagagcgtgt      180

ccctgcctgc ggaacctgac ttgtatatat tcaaagaatg agaaatggct tagcatcgcc      240

tatggccgtt gtcagaaaat tggaaggcag aagttggcta agaaaatgtt cttc            294


<210>  4866
<211>  2976
<212>  DNA
<213>  Homo Sapiens

<400>  4866
ctccgagggt cgaggaagct cacagccgct gcccctgggg ctgtcccaca cacatccact       60

gaaacccagg caagcagatg caagaaagga ttctctcagg acaaacagtg cttccttctc      120

tctggtaatg cccaggaaac cagaaaggtc aaagaatcaa tggagacaca ctttggcagc      180

catggccgaa gggccatact ctacaggcct cctttctaca gcaaaacaga gcttcagcta      240

caccagcaca ttctgactca acatggctat acggttgtca tcgctgaaga aaggctcaat      300

gctggcctag ggccggggct actagaacaa ggtgatctgg gctcttggga tctgctcatt      360

tgcctgtctt ctaagaaagc agaaggaaca ccctgtatat ccaaggaagt catgtgccag      420

ttaggtttac atcaaaaggc aaacagatta ccagaaatac agcagccact ttgcagaaag      480

gaaggattat gtcaaatagt tagaagattc ccagaactgc aacttccagt gagtccctct      540

gtgtgtctgg atcagggaat gcaattaaag ccgagtactt cgagtcacct tttaaaaaca      600

gtgaagccac gtgtgtggaa accaggggac tggagtcgtg aacagctgaa tgaaacgaca      660

gtccttgctc cacatgaaac aatctttcga gccgaagatc tatctgtgat tcttaaagcg      720

tatgtgttgg tgacgtcctt aacccctttg cgtgcattca ttcattcgac gggcacagtt      780

tggaatccac caaagaaaaa acgcttcact gtcaagctgc aaacattttt tgagacattc      840

ctgagagcca gttcacctca acaggctttt gacattatga aggaagcaat tggcaaacta      900

ctgctagcgg ctgaagtatt cagtgaaaca tctactctgg gaccaaagac cttccataga      960

tgcagattct gctttcaact tctaactttt gatattggtt atggcagttt catgtaccct     1020

gtagtgctcc aggtacacga gcatttaaat tttcaagatt atgataatat ggattttgag     1080

gaccaaaata cagaagaatt ccttttaaat gacactttca attttctctt ccctaatgaa     1140

tcatcacttt ccatattttc tgagatattt cagagacttt ataggtcaga tgttttcaag     1200

ggcgaaaact atcaaaagga actaaatcag tgtctgtcct tagaagaaat taactcaatt     1260

atgactttca taaaggaact tggaagtctg ggacaattcc aactgctctt cccatctact     1320

actcctggga ttcagtcact gatgcatgaa ttttatgatg tggcaaatcc tgtgggaaat     1380

cctggctcag tcctgaccca atactggtct cttttaaatg tatttgaaca atttcagttc     1440

atgaataaaa agacacagcc acatccactg gaatggaatt ctttcacaga agataagaac     1500

attgaaaaac cacaagtgcc atttgatgca atagaaaata aaaaagctgc agttccacaa     1560

attaaaaatg aaaataaaga aatacattgc agtgatgatg aaaacacacc atgtcatatc     1620

aagcagatct tcacacatcc acatttggaa ctaaatcctg actttcatcc aaagatcaaa     1680

gattattact gtgaagtccc atttgatgtg gtaacagtga caattggagt ggaaactcct     1740

aagtgtctgt gcaaggtgca cctgtacgag caggcagggc caagctttgc cagctaccct     1800

ctgggcttag gaatgaacaa aatctcaata tttgttgtgg atgaatctcc agcacacggt     1860

gagactctga tcacgtacaa actcaccatc tatagagaag accgcccaag tctgcccttg     1920

tttgaggcct tcacagcatg tggttttgtg caggattgtg gtttgctgat tcatccagag     1980

gaaacctgtg ggttacagcc tatttcttct gactacattg gagccatttt acagtctgaa     2040

ctaaaaagat gtccatctgg ggacatgaaa ggccagtgga ttgtgccttg ccttagttgt     2100

tcggacaaca ggacgtgtga ctggagagaa ataacctggc agccccacaa ctgccaatat     2160

ggtgtcctaa ctaagcctca actccagcag tgcctgggag gaaggaagat tctgttcatt     2220

ggagattcaa ccaacagagg gatcatgtac tatcttattg aaaggctgaa tgaaacgttg     2280

caggaatggc agaaagtaca tggcactaaa ttctatcaca acgtcaatgg tgggaagact     2340

ttgatcagtt attcctacta tccccagttc tggataagcc cttcattgag accaacattt     2400

gaaaatgcac ttgaacacct cttgcaaaga tcacgtcccc tagagaatac tggccagact     2460

gtattggttg ttggtggtgt tcagtggctt aattccaatc acctgcaaat tattcacaaa     2520

gttttgaaga gggaaaattt actcaatatc ctagtgatca tcaaaacttt gggaattgga     2580

tttcatctgc cagtggatgg agtacatttc ttaacacaga gtgaagtaca gaacttatgg     2640

aaagaaaatt tgattattct ggatactgca aaaaaacatg gctatgaagt agttgacaca     2700

ttcactataa caatggggcg ttacaaagag tttctacagg ggaagtgtgg atgtcatttc     2760

catgaggtag tgaaatcaaa gttatccaaa gaatataact ttattaaaat gaaaagatca     2820

agaaatcata tcatgggaag atatttcagc aatcaaagca aactacaaca aggcactgta     2880

acaaattttc gatcgccata tcatgtcaga ggtccaataa atcaggtttg ttctgaaatc     2940

cttctcagca ggatgtgtgc aaataaaagg actatg                               2976


<210>  4867
<211>  648
<212>  DNA
<213>  Homo Sapiens

<400>  4867
tctgttcaga aagaagaccc tgctccctat ttggtgtacc tcaagtctca cttcaacccc       60

tgtgtgggcg tcctcatcaa acccagctgg gtgctggccc cagctcactg ctatttacca      120

aatctgaaag tgatgctggg aaatttcaag agcagagtca gagacggtac tgaacagaca      180

attaacccca ttcagatcgt ccgctactgg aactacagtc atagcgcccc acaggatgac      240

ctcatgctca tcaagctggc taagcctgcc atgctcaatc ccaaagtcca gccccttacc      300

ctcgccacca ccaatgtcag gccaggcact gtctgtctac tctcaggttt ggactggagc      360

caagaaaaca gtggccgaca ccctgacttg cggcagaacc tggaggcccc cgtgatgtct      420

gatcgagaat gccaaaaaac agaacaagga aaaagccaca ggaattcctt atgtgtgaaa      480

tttgtgaaag tattcagccg aatttttggg gaggtggccg ttgctactgt catctgcaaa      540

gacaagctcc agggaatcga ggtggggcac ttcatgggag gggacgtcgg catctacacc      600

aatgtttaca aatatgtatc ctggattgag aacactgcta aggacaag                   648


<210>  4868
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  4868
gttactttca ccatcaattg ctcagggttt ggccagcacg gggcggatcc cactactctg       60

aattcagtgt ttaatagaaa gcccttccgt ccggtcacca acatcagcgt ccccacccaa      120

gtcaacatct ccttcgcgat gtctgccatc ctagatgtga atgaacagct gcacctcttg      180

tcatcattcc tgtggctgga aatggtttgg gataacccat ttatcagctg gaacccagag      240

gaatgtgagg gcatcacgaa gatgagtatg gcagccaaga acctgtggct cccagacatt      300

ttcatcattg aactcatgga tgtggataag accccaaaag gcctcacagc atatgtaagt      360

aatgaaggtc gcatcaggta taagaaaccc atgaaggtgg acagtatctg taacctggac      420

atcttctact tccccttcga ccagcagaac tgcacactca ccttcagctc attcctctac      480

acagtggaca gcatgttgct ggacatggag aaagaagtgt gggaaataac agacgcatcc      540

cggaacatcc ttcagaccca tggagaatgg gagctcctgg gcctcagcaa ggccaccgca      600

aagttgtcca ggggaggcaa cctgtatgat cagatcgtgt tctatgtggc catcaggcgc      660

aggcccagc                                                              669


<210>  4869
<211>  879
<212>  DNA
<213>  Homo Sapiens

<400>  4869
ctcctcttca tttaccaaga ggtgtccagg ctgtggtcaa agtcagctgt gcagaacaaa       60

gtggtggtga tcaccgatgc catctcagga ctgggcaagg agtgtgctcg ggtgttccac      120

acaggtgggg caaggctggt gctgtgtgga aagaactggg agaggctaga gaacctatat      180

gatgccttga tcagcgtggc tgaccccagc aagacattca ccccaaagct ggtcctgttg      240

gacctctcag acatcagctg tgtcccagat gtggcaaaag aagtcctgga ttgctatggc      300

tgtgtggaca tcctcatcaa caatgccagt gtgaaggtga aggggcctgc ccataagatt      360

tctctggagc tcgacaaaaa gatcatggat gccaattact ttggccccat cacattgacg      420

aaagccctgc ttcccaacat gatctcccgg agaacaggcc aaatcgtgtt agtgaataat      480

atccaaggga agtttggaat cccgttccgt acgacttacg ctgcctccaa gcacgcagcc      540

ctgggcttct ttgactgcct ccgagccgaa gtggaggaat acgatgttgt catcagcacc      600

gtgagcccga ctttcatccg gtcgtaccac gtgtatccag agcaaggaaa ctgggaagct      660

tccatttgga aattcttttt caggaagctg acctacggcg tgcacccagt agaggtggcg      720

gaggaggtga tgcgcaccgt gcggaggaag aagcaagagg tgtttatggc caaccccatc      780

cccaaggccg ccgtgtacgt ccgcaccttc ttcccggagt tctttttcgc cgtggtggcc      840

tgtggggtga aggagaagct caatgtcccg gaggagggg                             879


<210>  4870
<211>  2679
<212>  DNA
<213>  Homo Sapiens

<400>  4870
aattcactca ttcagctgaa caacaatggc tatgaaggca ttgtcgttgc aatcgacccc       60

aatgtgccag aagatgaaac actcattcaa caaataaagg acatggtgac ccaggcatct      120

ctgtatctgt ttgaagctac aggaaagcga ttttatttca aaaatgttgc cattttgatt      180

cctgaaacat ggaagacaaa ggctgactat gtgagaccaa aacttgagac ctacaaaaat      240

gctgatgttc tggttgctga gtctactcct ccaggtaatg atgaacccta cactgagcag      300

atgggcaact gtggagagaa gggtgaaagg atccacctca ctcctgattt cattgcagga      360

aaaaagttag ctgaatatgg accacaaggt agggcatttg tccatgagtg ggctcatcta      420

cgatggggag tatttgacga gtacaataat gatgagaaat tctacttatc caatggaaga      480

atacaagcag taagatgttc agcaggtatt actggtacaa atgtagtaaa gaagtgtcag      540

ggaggcagct gttacaccaa aagatgcaca ttcaataaag taacaggact ctatgaaaaa      600

ggatgtgagt ttgttctcca atcccgccag acggagaagg cttctataat gtttgcacaa      660

catgttgatt ctatagttga attctgtaca gaacaaaacc acaacaaaga agctccaaac      720

aagcaaaatc aaaaatgcaa tctccgaagc acatgggaag tgatccgtga ttctgaggac      780

tttaagaaaa ccactcctat gacaacacag ccaccaaatc ccaccttctc attgctgcag      840

attggacaaa gaattgtgtg tttagtcctt gacaaatctg gaagcatggc gactggtaac      900

cgcctcaatc gactgaatca agcaggccag cttttcctgc tgcagacagt tgagctgggg      960

tcctgggttg ggatggtgac atttgacagt gctgcccatg tacaaaatga actcatacag     1020

ataaacagtg gcagtgacag ggacacactc gccaaaagat tacctgcagc agcttcagga     1080

gggacgtcca tctgcagcgg gcttcgatcg gcatttactg tgattaggaa gaaatatcca     1140

actgatggat ctgaaattgt gctgctgacg gatggggaag acaacactat aagtgggtgc     1200

tttaacgagg tcaaacaaag tggtgccatc atccacacag tcgctttggg gccctctgca     1260

gctcaagaac tagaggagct gtccaaaatg acaggaggtt tacagacata tgcttcagat     1320

caagttcaga acaatggcct cattgatgct tttggggccc tttcatcagg aaatggagct     1380

gtctctcagc gctccatcca gcttgagagt aagggattaa ccctccagaa cagccagtgg     1440

atgaatggca cagtgatcgt ggacagcacc gtgggaaagg acactttgtt tcttatcacc     1500

tggacaatgc agcctcccca aatccttctc tgggatccca gtggacagaa gcaaggtggc     1560

tttgtagtgg acaaaaacac caaaatggcc tacctccaaa tcccaggcat tgctaaggtt     1620

ggcacttgga aatacagtct gcaagcaagc tcacaaacct tgaccctgac tgtcacgtcc     1680

cgtgcgtcca atgctaccct gcctccaatt acagtgactt ccaaaacgaa caaggacacc     1740

agcaaattcc ccagccctct ggtagtttat gcaaatattc gccaaggagc ctccccaatt     1800

ctcagggcca gtgtcacagc cctgattgaa tcagtgaatg gaaaaacagt taccttggaa     1860

ctactggata atggagcagg tgctgatgct actaaggatg acggtgtcta ctcaaggtat     1920

ttcacaactt atgacacgaa tggtagatac agtgtaaaag tgcgggctct gggaggagtt     1980

aacgcagcca gacggagagt gataccccag cagagtggag cactgtacat acctggctgg     2040

attgagaatg atgaaataca atggaatcca ccaagacctg aaattaataa ggatgatgtt     2100

caacacaagc aagtgtgttt cagcagaaca tcctcgggag gctcatttgt ggcttctgat     2160

gtcccaaatg ctcccatacc tgatctcttc ccacctggcc aaatcaccga cctgaaggcg     2220

gaaattcacg ggggcagtct cattaatctg acttggacag ctcctgggga tgattatgac     2280

catggaacag ctcacaagta tatcattcga ataagtacaa gtattcttga tctcagagac     2340

aagttcaatg aatctcttca agtgaatact actgctctca tcccaaagga agccaactct     2400

gaggaagtct ttttgtttaa accagaaaac attacttttg aaaatggcac agatcttttc     2460

attgctattc aggctgttga taaggtcgat ctgaaatcag aaatatccaa cattgcacga     2520

gtatctttgt ttattcctcc acagactccg ccagagacac ctagtcctga tgaaacgtct     2580

gctccttgtc ctaatattca tatcaacagc accattcctg gcattcacat tttaaaaatt     2640

atgtggaagt ggataggaga actgcagctg tcaatagcc                            2679


<210>  4871
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  4871
atccggctgg tgcccccgta cccaagcagc caagaggacc ccatccacat cgcatgcatg       60

gcccctggga acttcccggg ggcgaatttc acactgtatc gaggggggca ggtggtccag      120

ctcctgcagg cccccacgga ccagcgcggg gtgacattta acctgagcgg cggcagcagc      180

aaggctccag ggggaccctt ccactgccag tatggagtgt taggtgagct caaccagtcc      240

cagctgtcag acctcagcga gcccgtgaac gtctccttcc cagtgcccac ttgg            294


<210>  4872
<211>  942
<212>  DNA
<213>  Homo Sapiens

<400>  4872
caggacacct gcaggcaagg gcaccctgga atccctggga accccggtca caatggtctg       60

cctggaagag atggacgaga cggagcgaag ggtgacaaag gcgatgcagg agaaccagga      120

tgtcctggca gcccggggaa ggatgggacg agtggagaga agggagaacg aggagcagat      180

ggaaaagttg aagcaaaagg catcaaaggt gatcaaggct caagaggatc cccaggaaaa      240

catggcccca aggggcttgc agggcccatg ggagagaaag gcctccgagg agagactggg      300

cctcaggggc agaaggggaa taagggtgac gtgggtccca ctggtcctga ggggccaagg      360

ggcaacattg ggcctttggg cccaactggt ttaccgggcc ccatgggccc tattggaaag      420

cctggtccca agggagaagc tggacccacg gggccccagg gtgagccagg agtccgggga      480

ataagaggct ggaaaggaga tcgaggagag aaagggaaaa tcggtgagac tctagtcttg      540

ccaaaaagtg ctttcactgt ggggctcacg gtgctgagca agtttccttc ttcagatgtg      600

cccattaaat ttgataagat cctgtataac gaattcaacc attatgatac agcagtgggg      660

aaattcacgt gccacattgc tggggtctat tacttcacct accacatcac tgttttctcc      720

aggaatgttc aggtgtcttt ggtcaaaaac ggagtaaaaa tactgcacac cagagatgct      780

tacgtgagct ctgaggacca ggcctctggc agcattgtcc tgcagctgaa gctcggggat      840

gagatgtggc tgcaggtgac aggaggagag aggttcaatg gcttgtttgc tgatgaggac      900

gatgacacaa ctttcacagg gttccttctg ttcagcagcc ag                         942


<210>  4873
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  4873
gctgctatca gtcatgaaga ctatcctgct gatgaaggtg accagatctc cagtaatgac       60

aatctgatct ttgatgacta tcgagggaaa gggtgtgtcg atgacagcgg ctttgtatac      120

aagttgggag aacgattttt ccctgggcat tccaactgtc catgtgtctg tgctctagat      180

ggacctgttt gcgaccaacc agaatgccct aaaattcacc caaagtgtac taaagtggaa      240

cacaatggat gctgtcctga gtgcaaagaa gtaaaaaact tctgtgaata tcacgggaaa      300

aattacaaaa tcttggagga atttaagccc tctccatgtg aatggtgtcg ctgtgagccc      360

agcaatgaag ttcactgtgt tgtagcagac tgcgcagttc ctgagtgtgt caacccagtc      420

tatgaaccag aacaatgttg tcctgtctgc aaaaatggtc caaactgctt tgcaggaacg      480

acgataattc cagctggcat tgaagtgaaa gtggacgaat gtaacatctg tcattgtcac      540

aacggggact ggtggaagcc tgctcagtgt tcgaaacgtg aatgccaagg caagcagact      600

gtg                                                                    603


<210>  4874
<211>  405
<212>  DNA
<213>  Homo Sapiens

<400>  4874
gacctggaca ctgcagccag gcgaggccag caccaggtcc cccagcaccg cgggcacgtc       60

tgctacctgg gcgtatgccg gacccaccgc ctggcggaga tcatatactg gattcgctgt      120

ctccaccaag gagccctcgg ggaaggccag ccacgagccc caggacccct acagctatgg      180

gcgccgccgg tggcgcgagg cggaagcccg gctcggttcc caggattccg gcctgcagcg      240

agggggctag cgcagtgccc agctcgctgg gtgacctcgg gcacggctcg tcccctcctc      300

ggcttcagtt tgcctatctg tatgttggag cttctactcc acatttcttc tcccctaact      360

ccagcccctg aaaccgtctt ccccagtccc tccccgggct gcgac                      405


<210>  4875
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  4875
tgctacgggg actccgggca gcctgtagac tggttcgtgg tctacaagct gccagctctt       60

agagggtccg gggaggcggc gcagagaggg ctgcagtaca agtatctgga cgagagctcc      120

ggaggctggc gggacggcag ggcactcatc aacagcccgg agggggccgt gggccgaagc      180

ctgcagccgc tgtaccggag caacaccagc cagctcgcct tcctgctcta caatgaccaa      240

ccgcctcaac ccagcaaggc tcaggactct tccatgcgtg ggcacacgaa gggtgtcctg      300

ctccttgacc acgatggggg cttctggctg gtccacagtg tacctaactt ccctccaccg      360

gcctcctctg ctgcatacag ctggcctcat agcgcctgta cctacgggca gaccctgctc      420

tgtgtgtctt ttcccttcgc tcagttctcg aagatgggca agcagctgac ctacacctac      480

ccctgggtct ataactacca gctggaaggg atctttgccc aggaattccc cgacttggag      540

aatgtggtca agggccacca cgttagccaa gaaccctgga acagcagcat cacactcaca      600

tcccaggccg gggctgtttt ccagagcttt gccaagttca gcaaatttgg agatgacctg      660

tactccggct ggttggcagc agcccttggt accaacctgc aggtccagtt ctggcacaaa      720

actgtaggca tcctgccctc taactgctcg gatatctggc aggttctgaa tgtgaaccag      780

atagctttcc ctggaccagc cggcccaagc ttcaacagca cagaggacca ctccaaatgg      840

tgcgtgtccc caaaagggcc ctggacctgc gtgggtgaca tgaatcggaa ccagggagag      900

gagcaacggg gtgggggcac actgtgtgcc cagctgccag ccctctggaa agccttccag      960

ccgctggtga agaactacca gccctgtaat ggcatggcca ggaagcccag cagagcttat     1020

aagatc                                                                1026


<210>  4876
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  4876
ctggagatcg gccgcttcga cccggagcgc gggcgcgggg ctgcgccgtg ccaggcggtg       60

gagatcccca tgtgccgcgg catcggctac aacctgaccc gcatgcccaa cctgctgggc      120

cacacgtcgc agggcgaggc ggctgccgag ctagcggagt tcgcgccgct ggtgcagtac      180

ggctgccaca gccacctgcg cttcttcctg tgctcgctct acgcgcccat gtgcaccgac      240

caggtctcga cgcccattcc cgcctgccgg cccatgtgcg agcaggcgcg cctgcgctgc      300

gcgcccatca tggagcagtt caacttcggc tggccggact cgctcgactg cgcccggctg      360

cccacgcgca acgacccgca cgcgctgtgc atggaggcgc ccgagaacgc cacggccggc      420

cccgcggagc cccacaaggg cctgggcatg ctgcccgtgg cgccgcggcc cgcgcgccct      480

cccggagacc tgggcccggg cgcgggcggc agtggcacct gcgagaaccg cgagaagttc      540

cagtacgtgg agaagagccg ctcgtgcgca ccgcgctgcg ggcccggcgt cgaggtgttc      600

tggtcccggc gcgacaagga c                                                621


<210>  4877
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  4877
tcctcggtgg agctgcccta tgaggacctg ctgcgccagg agctgcgcaa gctgaagcga       60

cgcttcttgg aggagcacga gtgcctgtct gagcagcagc tggagcagtt cctgggccgg      120

gtgctggagg ccagcaacta cggcgtgtcg gtgctcagca acgcctcggg caactggaac      180

tgggac                                                                 186


<210>  4878
<211>  1068
<212>  DNA
<213>  Homo Sapiens

<400>  4878
atggccttca gcggttgcca ggctccctat ctgagcccag ccgtcccctt ttctgggact       60

atccaagggg gtctccagga cggatttcag atcactgtca atggggccgt tctcagctgc      120

agtggaacca ggtttgctgt ggactttcag acgggcttca gtggaaacga cattgccttc      180

cacttcaacc ctcggtttga agacggaggg tatgtggtgt gcaacacgag gcagaaagga      240

acatgggggc ccgaggagag gaagatgcac atgcccttcc agaaggggat gccctttgac      300

ctctgcttcc tggtgcagag ctcagatttc aaggtgatgg tgaacgggag cctcttcgtg      360

cagtacttcc accgcgtgcc cttccaccgt gtggacacca tctccgtcaa tggctctgtg      420

cagctgtcct acatcagctt ccagaatccc cgcgcagtcc ccgttcagcc tgccttctcc      480

acggtgccgt tctcccagcc tgtctgtttc ccacccaggc ccagggggcg cagacaaaaa      540

cctcccatcg tgcggcctgc caacccagct cccattaccc agacagtcat ccacacggtg      600

cagagtgcct ctggacagat gttctctcag actcccgcca tcccacctat gatgtacccc      660

caccctgcct atccgatgcc tttcatcacc accattccgg gagggctgta cccatccaag      720

tccatcatcc tgtcaggcac tgtcctgccc agtgctcaga ggttccacat caacctgtgc      780

tctgggagcc acatcgcctt ccacatgaac ccccgttttg atgagaatgc tgtggtccgt      840

aacacccaga tcaacaactc ttgggggtct gaggagcgaa gtctgccccg aaaaatgccc      900

ttcgtccgag gccagagctt ctcggtgtgg atcttgtgtg aagctcactg cctcaaggtg      960

gccgtggatg gtcagcacgt gtttgaatac taccatcgcc tgaggaacct gcccaccatc     1020

aacaaactgg aagtgggtgg cgacatccag ctgacccacg tgcagaca                  1068


<210>  4879
<211>  150
<212>  DNA
<213>  Homo Sapiens

<400>  4879
tcctcacgtc gctgcgtaag gctgcatgag tcctgcctgg gacagcaggt gccttgctgt       60

gacccatgtg ccacgtgcta ctgccgcttc ttcaatgcct tctgctactg ccgcaagctg      120

ggtactgcca tgaatccctg cagccgcacc                                       150


<210>  4880
<211>  870
<212>  DNA
<213>  Homo Sapiens

<400>  4880
aggttcagcc agagcttccg agaggtggcc ggcaggttcc tggcgtcgga ggccagcaca       60

cacctgctgg tgttcggcat ggagcagcgg ctgccgccca acagcgagct ggtgcaggcc      120

gtgctgcggc tcttccagga gccggtcccc aaggccgcgc tgcacaggca cgggcggctg      180

tccccgcgca gcgcccaggc ccgggtgacc gtcgagtggc tgcgcgtccg cgacgacggc      240

tccaaccgca cctccctcat cgactccagg ctggtgtccg tccacgagag cggctggaag      300

gccttcgacg tgaccgaggc cgtgaacttc tggcagcagc tgagccggcc ccggcagccg      360

ctgctgctac aggtgtcggt gcagagggag catctgggcc cgctggcgtc cggcgcccac      420

aagctggtcc gctttgcctc gcagggggcg ccagccgggc ttggggagcc ccagctggag      480

ctgcacaccc tggacctcag ggactatgga gctcagggcg actgtgaccc tgaagcacca      540

atgaccgagg gcacccgctg ctgccgccag gagatgtaca ttgacctgca ggggatgaag      600

tgggccaaga actgggtgct ggagcccccg ggcttcctgg cttacgagtg tgtgggcacc      660

tgccagcagc ccccggaggc cctggccttc aattggccat ttctggggcc gcgacagtgt      720

atcgcctcgg agactgcctc gctgcccatg atcgtcagca tcaaggaggg aggcaggacc      780

aggccccagg tggtcagcct gcccaacatg agggtgcaga agtgcagctg tgcctcggat      840

ggggcgctcg tgccaaggag gctccagcca                                       870


<210>  4881
<211>  1560
<212>  DNA
<213>  Homo Sapiens

<400>  4881
atgtctcagg ataatgacac attgatgaga gacatcctgg ggcatgagct cgctgctatg       60

aggctgcaga agctggaaca gcagcggcgg ctgtttgaaa agaagcagcg acagaagcgc      120

caggagctcc tcatggttca ggccaatcct gacgcttccc cgtggctttg gcgctcttgt      180

ctgcgggagg agcgcctttt aggtgacaga ggccttggga accctttcct ccggaagaaa      240

gtgtcagagg cacatctgcc ctctggcatc cacagtgccc tgggcaccgt gagctgtggt      300

ggagacggca ggggcgagcg cggcctcccg acaccgcgga cagaagcagt gttcaggaat      360

ctcggtctcc agtccccttt cttatcctgg ctcccagaca attccgatgc agaattggag      420

gaagtctccg tggagaatgg ttccgtctct cccccacctt ttaaacagtc tccgagaatc      480

cgacgcaagg gttggcaagc ccaccaacga cctgggaccc gtgcagaggg tgagagtgac      540

tcccaggata tgggagatgc acacaagtca cccaatatgg gaccaaaccc tggaatggat      600

ggtgactgtg tatatgaaaa cttggccttc caaaaggaag aagacttgga aaagaagaga      660

gaggcctctg agtctacagg gacgaactcc tcagcagcac acaacgaaga gttgtccaag      720

gccctgaaag gcgagggtgg cacggacagc gaccatatga ggcacgaagc ctccttggca      780

atccgctccc cctgccctgg gctggaggag gacatggaag cctacgtgct gcggccagcg      840

ctcccgggca ccatgatgca gtgctacctc acccgtgaca agcacggcgt ggacaagggc      900

ttgttccccc tctactacct ctacctggag acctctgaca gcctgcagcg cttcctcctg      960

gctgggcgaa agagaagaag gagcaaaact tctaattacc tcatctccct ggatcctaca     1020

cacctatctc gggacgggga caatttcgtg ggcaaagtca gatccaatgt cttcagcacc     1080

aagttcacca tctttgacaa tggggtgaat cctgaccggg agcatttaac caggaatact     1140

gcccggatca gacaggagct gggggctgtg tgttatgagc ccaacgtctt aggatacctg     1200

gggcctcgga aaatgactgt gattctccca ggaaccaaca gccagaacca gcgaatcaat     1260

gtccagccac taaatgaaca ggagtcgcta ctgagtcgtt accaacgtgg ggacaaacaa     1320

gggttgcttt tgttgcacaa caaaaccccg tcgtgggaca aggagaacgg tgtctacacg     1380

ctcaatttcc atggtcgagt cactcgggct tcggtgaaga acttccaaat cgtggatccc     1440

aaacaccaag aacatctggt gctccagttc ggccgagtgg gcccagacac attcaccatg     1500

gacttctgct ttccatttag cccgctccag gccttcagca tctgcttgtc cagtttcaat     1560


<210>  4882
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  4882
atggctgtca gcaggaagga ctggtccgcg ctgtccagcc ttgcccggca gaggactctg       60

gaggatgagg aggaacagga gcgcgagcgc aggcggcggc accgcaacct gagctccacc      120

acggacgatg aggctcccag gctcagccag aatggagacc ggcaggcctc tgcttctgag      180

agactaccga gcgtggaaga agcagaggtg cccaagccac tgcccccagc ctccaaagat      240

gaggacgagg acatccagag catcctcaga acacggcagg agcggaggca gaggcggcag      300

gtggtggagg ctgcacaggc ccccatccag gagaggctgg aggcagagga ggggaggaac      360

agcttgagcc ctgtgcaggc cacacagaaa cccctagtct ccaagaagga actggaaatc      420

ccacctcgcc ggagactgag tcgggaacag cggggcccct gggccctgga ggaggagagc      480

ttggtgggca gggagccaga agagaggaag aaaggggttc cagaaaagtc cccagtcttg      540

gagaagtcct ccatgccaaa gaagacggca cctgaaaaga gcctggtctc cgataaaacc      600

tccatctctg agaaggtgct ggcctcagag aagacatctc tatcagagaa gatagcagtg      660

tcagagaaaa gaaacagctc agagaagaag tctgttctag aaaaaaccag tgtctctgag      720

aagtcgctgg ccccagggat ggcactgggc tcaggaagga ggctggtgtc tgagaaagct      780

tccatctttg agaaggcact ggcctcagag aagagcccaa ctgcagatgc taagccggcc      840

ccaaagaggg ccacagcctc agagcagccc ctggcgcagg agccgccagc ctctggggga      900

agcccagcca ccaccaagga gcagagagga agggccctcc ctgggaagaa cctgccctct      960

ttggcaaagc agggggcttc agaccctccg actgtggcct cccgcctccc acccgtcaca     1020

ctccaggtga aaatccccag caaggaggaa gaggcagata tgtcctcacc cacacagcga     1080

acctacagca gctccctcaa acgctccagc cccaggacca tctcctttcg gatgaaaccc     1140

aagaaagaaa actcggaaac aaccctaact cgcagtgcca gcatgaagct cccagacaac     1200

acagtgaagt tgggagagaa gctggagaga taccacacgg ccatacggag atcagaatct     1260

gtcaagtctc ggggtctgcc ttgcactgag ttattcgtgg ctcctgtggg tgtagccagc     1320

aagcgccacc tctttgagaa ggaactggcg ggccagagcc gagcagaacc agcctccagc     1380

cggaaggaga acttgaggct ctcaggggtt gtgacatcaa ggctcaacct gtggatcagc     1440

aggacccagg aatctggaga tcaggacccc caggaggcac agaaagcatc atctgcaacc     1500

gagaggactc agtggggaca gaaatctgac tcctcgctgg acgctgaggt g              1551


<210>  4883
<211>  891
<212>  DNA
<213>  Homo Sapiens

<400>  4883
tctctctatc catctctcga agacttgaag gtagacaaag taattcaggc tcaaactgct       60

ttttctgcaa accctgccaa tccagcaatt ttgtcagaag cttctgctcc tatccctcac      120

gatggaaatc tctatcccag actgtatcca gagctctctc aatacatggg gctgagttta      180

aatgaagaag aaatacgtgc aaatgtggcc gtggtttctg gtgcaccact tcaggggcag      240

ttggtagcaa gaccttccag tataaactat atggtggctc ctgtaactgg taatgatgtt      300

ggaattcgta gagcagaaat taagcaaggg attcgtgaag tcattttgtg taaggatcaa      360

gatggaaaaa ttggactcag gcttaaatca atagataatg gtatatttgt tcagctagtc      420

caggctaatt ctccagcctc attggttggt ctgagatttg gggaccaagt acttcagatc      480

aatggtgaaa actgtgcagg atggagctct gataaagcgc acaaggtgct caaacaggct      540

tttggagaga agattaccat gaccattcgt gacaggccct ttgaacggac gattaccatg      600

cataaggata gcactggaca tgttggtttt atctttaaaa atggaaaaat aacatccata      660

gtgaaagata gctctgcagc cagaaatggt cttctcacgg aacataacat ctgtgaaatc      720

aatggacaga atgtcattgg attgaaggac tctcaaattg cagacatact gtcaacatct      780

gggactgtag ttactattac aatcatgcct gcttttatct ttgaacatat tattaagcgg      840

atggcaccaa gcattatgaa aagcctaatg gaccacacca ttcctgaggt t               891


<210>  4884
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  4884
gacaagcgcc tgcgtgacaa ccatgagtgg aaaaaactaa ttatggttca gcactggcct       60

gagacagtat gcgagaaaat tcaaaacgac tgtagagacc ctccggatta ctggacaata      120

catggactat ggcccgataa aagtgaagga tgtaatagat cgtggccctt caatttagaa      180

gagattaagg atcttttgcc agaaatgagg gcatactggc ctgacgtaat tcactcgttt      240

cccaatcgca gccgcttctg gaagcatgag tgggaaaagc atgggacctg cgccgcccag      300

gtggatgcgc tcaactccca gaagaagtac tttggcagaa gcctggaact ctacagggag      360

ctggacctca acagtgtgct tctaaaattg gggataaaac catccatcaa ttactaccaa      420

gttgcagatt ttaaagatgc ccttgccaga gtatatggag tgatacccaa aatccagtgc      480

cttccaccaa gccaggatga ggaagtacag acaattggtc agatagaact gtgcctcact      540

aagcaagacc agcagctgca aaactgcacc gagccggggg agcagccgtc ccccaagcag      600

gaagtctggc tggcaaatgg ggccgccgag agccggggtc tgagagtctg tgaagatggc      660

ccagtcttct atcccccacc taaaaagacc aagcat                                696


<210>  4885
<211>  150
<212>  DNA
<213>  Homo Sapiens

<400>  4885
atggccgcca ctgcctctcc gcagccactc gccactgagg atgccgattc tgagaatagc       60

agcttctatt actatgacta cctggatgaa gtggccttca tgctctgcag gaaggatgca      120

gtggtgtcct ttggcaaagt cttcctccca                                       150


<210>  4886
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  4886
gagaggatgt gcatccaggg gagtcagttc aacgtcgagg tcggcagaag tgacaagctt       60

tccctgcctg gctttgagaa cctcacagca ggatataaca aatttctcag gcccaatttt      120

ggtggagaac ccgtacagat agcgctgact ctggacattg caagtatctc tagcatttca      180

gagagtaaca tggactacac agccaccata tacctccgac agcgctggat ggaccagcgg      240

ctggtgtttg aaggcaacaa gagcttcact ctggatgccc gcctcgtgga gttcctctgg      300

gtgccagata cttacattgt ggagtccaag aagtccttcc tccatgaagt cactgtggga      360

aacaggctca tccgcctctt ctccaatggc acggtcctgt atgccctcag aatcacgaca      420

actgttgcat gtaacatgga tctgtctaaa taccccatgg acacacagac atgcaagttg      480

cagctggaaa gctggggcta tgatggaaat gatgtggagt tcacctggct gagagggaac      540

gactctgtgc gtggactgga acacctgcgg cttgctcagt acaccataga gcggtatttc      600

accttagtca ccagatcgca gcaggagaca ggaaattaca ctagattggt cttacagttt      660

gagcttcgga ggaatgtt                                                    678


<210>  4887
<211>  1221
<212>  DNA
<213>  Homo Sapiens

<400>  4887
tcgccgtcgc cgtcgccgtc gccctcccag aatgcaaccc agactactac ggactcatct       60

aacaaaacag caccgactcc agcatccagt gtcaccatca tggctacaga tacagcccag      120

cagagcacag tccccacttc caaggccaac gaaatcttgg cctcagtcaa ggcgaccacc      180

cttggtgtat ccagtgactc accggggact acaaccctgg ctcagcaagt ctcaggccca      240

gtcaacacta ccgtggctag aggaggcggc tcaggcaacc ctactaccac catcgagagc      300

cccaagagca caaaaagtgc agacaccact acagttgcaa cctccacagc cacagctaaa      360

cctaacacca caagcagcca gaatggagca gaagatacaa caaactctgg ggggaaaagc      420

agccacagtg tgaccacaga cctcacatcc actaaggcag aacatctgac gacccctcac      480

cctacaagtc cacttagccc ccgacaaccc acttcgacgc atcctgtggc caccccaaca      540

agctcgggac atgaccatct tatgaaaatt tcaagcagtt caagcactgt ggctatccct      600

ggctacacct tcacaagccc ggggatgacc accaccctac cgtcatcggt tatctcgcaa      660

agaactcaac agacctccag tcagatgcca gccagctcta cggccccttc ctcccaggag      720

acagtgcagc ccacgagccc ggcaacggca ttgagaacac ctaccctgcc agagaccatg      780

agctccagcc ccacagcagc atcaactacc caccgatacc ccaaaacacc ttctcccact      840

gtggctcatg agagtaactg ggcaaagtgt gaggatcttg agacacagac acagagtgag      900

aagcagctcg tcctgaacct cacaggaaac accctctgtg cagggggcgc ttcggatgag      960

aaattgatct cactgatatg ccgagcagtc aaagccacct tcaacccggc ccaagataag     1020

tgcggcatac ggctggcatc tgttccagga agtcagaccg tggtcgtcaa agaaatcact     1080

attcacacta agctccctgc caaggatgtg tacgagcggc tgaaggacaa atgggatgaa     1140

ctaaaggagg caggggtcag tgacatgaag ctaggggacc aggggccacc ggaggaggcc     1200

gaggaccgct tcagcatgcc c                                               1221


<210>  4888
<211>  891
<212>  DNA
<213>  Homo Sapiens

<400>  4888
gcggacacat gtccagaggt gaaggtggtg ggcctggagg gctctgacaa gctcaccatt       60

ctccgaggct gcccggggct gcccggggcc ccagggccaa agggagaggc aggtgtcatt      120

ggagagagag gagaacgcgg tctccctgga gcccctggaa aggcaggacc agtggggccc      180

aaaggagacc gaggagagaa ggggatgcgt ggagagaaag gagacgctgg gcagtctcag      240

tcgtgtgcga caggcccacg caactgcaag gacctgctag accgggggta tttcctgagc      300

ggctggcaca ccatctacct gcccgactgc cggcccctga ctgtgctctg tgacatggac      360

acggacggag ggggctggac cgttttccag cggaggatgg atggctctgt ggacttctat      420

cgggactggg ccgcatacaa gcagggcttc ggcagtcagc tgggggagtt ctggctgggg      480

aacgacaaca tccacgccct gactgcccag ggaagcagcg agctccgtgt agacctggtg      540

gactttgagg gcaaccacca gtttgctaag tacaaatcat tcaaggtggc tgacgaggca      600

gagaagtaca agctggtact gggagccttt gtcgggggca gtgcgggtaa ttctctaacg      660

ggccacaaca acaacttctt ctccaccaaa gaccaagaca atgatgtgag ttcttcgaat      720

tgtgctgaga agttccaggg agcctggtgg tacgccgact gtcatgcttc aaacctcaat      780

ggtctctacc tcatgggacc ccatgagagc tatgccaatg gtatcaactg gagtgcggcg      840

aaggggtaca aatatagcta caaggtgtca gagatgaagg tgcggcccgc c               891


<210>  4889
<211>  1071
<212>  DNA
<213>  Homo Sapiens

<400>  4889
acctgccccg ctgcctgcca ctgccccctg gaggcgccca agtgcgcgcc gggagtcggg       60

ctggtccggg acggctgcgg ctgctgtaag gtctgcgcca agcagctcaa cgaggactgc      120

agcaaaacgc agccctgcga ccacaccaag gggctggaat gcaacttcgg cgccagctcc      180

accgctctga aggggatctg cagagctcag tcagagggca gaccctgtga atataactcc      240

agaatctacc aaaacgggga aagtttccag cccaactgta aacatcagtg cacatgtatt      300

gatggcgccg tgggctgcat tcctctgtgt ccccaagaac tatctctccc caacttgggc      360

tgtcccaacc ctcggctggt caaagttacc gggcagtgct gcgaggagtg ggtctgtgac      420

gaggatagta tcaaggaccc catggaggac caggacggcc tccttggcaa ggagctggga      480

ttcgatgcct ccgaggtgga gttgacgaga aacaatgaat tgattgcagt tggaaaaggc      540

agctcactga agcggctccc tgtttttgga atggagcctc gcatcctata caacccttta      600

caaggccaga aatgtattgt tcaaacaact tcatggtccc agtgctcaaa gacctgtgga      660

actggtatct ccacacgagt taccaatgac aaccctgagt gccgccttgt gaaagaaacc      720

cggatttgtg aggtgcggcc ttgtggacag ccagtgtaca gcagcctgaa aaagggcaag      780

aaatgcagca agaccaagaa atcccccgaa ccagtcaggt ttacttacgc tggatgtttg      840

agtgtgaaga aataccggcc caagtactgc ggttcctgcg tggacggccg atgctgcacg      900

ccccagctga ccaggactgt gaagatgcgg ttccgctgcg aagatgggga gacattttcc      960

aagaacgtca tgatgatcca gtcctgcaaa tgcaactaca actgcccgca tgccaatgaa     1020

gcagcgtttc ccttctacag gctgttcaat gacattcaca aatttaggga c              1071


<210>  4890
<211>  1083
<212>  DNA
<213>  Homo Sapiens

<400>  4890
aatgagattc tgggcctgaa gttgcctggc gagccgccgc tgacggccaa caccgtgtgc       60

ttgacgctgt ccggcctgag caagcggcag ctaggcctgt gcctgcgcaa ccccgacgtg      120

acggcgtccg cgcttcaggg tctgcacatc gcggtccacg agtgtcagca ccagctgcgc      180

gaccagcgct ggaactgctc cgcgcttgag ggcggcggcc gcctgccgca ccacagcgcc      240

atcctcaagc gcggtttccg agaaagtgct ttttccttct ccatgctggc tgctggggtc      300

atgcacgcag tagccacggc ctgcagcctg ggcaagctgg tgagctgtgg ctgtggctgg      360

aagggcagtg gtgagcagga tcggctgagg gccaaactgc tgcagctgca ggcactgtcc      420

cgaggcaaga gtttccccca ctctctgccc agccctggcc ctggctcaag ccccagccct      480

ggcccccagg acacatggga atggggtggc tgtaaccatg acatggactt tggagagaag      540

ttctctcggg atttcttgga ttccagggaa gctccccggg acatccaggc acgaatgcga      600

atccacaaca acagggtggg gcgccaggtg gtaactgaaa acctgaagcg gaaatgcaag      660

tgtcatggca catcaggcag ctgccagttc aagacatgct ggagggcggc cccagagttc      720

cgggcagtgg gggcggcgtt gagggagcgg ctgggccggg ccatcttcat tgatacccac      780

aaccgcaatt ctggagcctt ccagccccgt ctgcgtcccc gtcgcctctc aggagagctg      840

gtctactttg agaagtctcc tgacttctgt gagcgagacc ccactatggg ctccccaggg      900

acaaggggcc gggcctgcaa caagaccagc cgcctgttgg atggctgtgg cagcctgtgc      960

tgtggccgtg ggcataacgt gctccggcag acacgagttg agcgctgcca ttgccgcttc     1020

cactggtgct gctatgtgct gtgtgatgag tgcaaggtta cagagtgggt gaatgtgtgt     1080

aag                                                                   1083


<210>  4891
<211>  1599
<212>  DNA
<213>  Homo Sapiens

<400>  4891
caggactcag ccagtcccat ccggaccaca cacacggggc aggtgctggg gagtcttgtc       60

catgtgaagg gcgccaatgc cggggtccaa accttcctgg gaattccatt tgccaagcca      120

cctctaggtc cgctgcgatt tgcaccccct gagccccctg aatcttggag tggtgtgagg      180

gatggaacca cccatccggc catgtgtcta caggacctca ccgcagtgga gtcagagttt      240

cttagccagt tcaacatgac cttcccttcc gactccatgt ctgaggactg cctgtacctc      300

agcatctaca cgccggccca tagccatgaa ggctctaacc tgccggtgat ggtgtggatc      360

cacggtggtg cgcttgtttt tggcatggct tccttgtatg atggttccat gctggctgcc      420

ttggagaacg tggtggtggt catcatccag taccgcctgg gtgtcctggg cttcttcagc      480

actggagaca agcacgcaac cggcaactgg ggctacctgg accaagtggc tgcactacgc      540

tgggtccagc agaatatcgc ccactttgga ggcaaccctg accgtgtcac catttttggc      600

gagtctgcgg gtggcacgag tgtgtcttcg cttgttgtgt cccccatatc ccaaggactc      660

ttccacggag ccatcatgga gagtggcgtg gccctcctgc ccggcctcat tgccagctca      720

gctgatgtca tctccacggt ggtggccaac ctgtctgcct gtgaccaagt tgactctgag      780

gccctggtgg gctgcctgcg gggcaagagt aaagaggaga ttcttgcaat taacaagcct      840

ttcaagatga tccccggagt ggtggatggg gtcttcctgc ccaggcaccc ccaggagctg      900

ctggcctctg ccgactttaa gcctgtccct agcattgttg gtgtcaacaa caatgaattc      960

ggctggctca tccccaaggt catgaggatc tatgataccc agaaggaaat ggacagagag     1020

gcctcccagg ctgctctgca gaaaatgtta acgctgctga tgttgcctcc tacatttggt     1080

gacctgctga gggaggagta cattggggac aatggggatc cccagaccct ccaagcgcag     1140

ttccaggaga tgatggcgga ctccatgttt gtgatccctg cactccaagt agcacatttt     1200

cagtgttccc gggcccctgt gtacttctac gagttccagc atcagcccag ctggctcaag     1260

aacatcaggc caccgcacat gaaggcagac catggtgatg agcttccttt tgttttcaga     1320

agtttctttg ggggcaacta cattaaattc actgaggaag aggagcagct aagcaggaag     1380

atgatgaagt actgggccaa ctttgcgaga aatgggaacc ccaatggcga gggtctgcca     1440

cactggccgc tgttcgacca ggaggagcaa tacctgcagc tgaacctaca gcctgcggtg     1500

ggccgggctc tgaaggccca caggctccag ttctggaaga aggcgctgcc ccaaaagatc     1560

caggagctcg aggagcctga agagagacac acagagctg                            1599


<210>  4892
<211>  2886
<212>  DNA
<213>  Homo Sapiens

<400>  4892
gggggatacg agacatgccc cacagtgcag ccgaacatgc tgaacgtgca cctgctgcct       60

cacacacatg atgacgtggg ctggctcaaa accgtggacc agtactttta tggaatcaag      120

aatgacatcc agcacgccgg tgtgcagtac atcctggact cggtcatctc tgccttgctg      180

gcagatccca cccgtcgctt catttacgtg gagattgcct tcttctcccg ttggtggcac      240

cagcagacaa atgccacaca ggaagtcgtg cgagaccttg tgcgccaggg gcgcctggag      300

ttcgccaatg gtggctgggt gatgaacgat gaggcagcca cccactacgg tgccatcgtg      360

gaccagatga cacttgggct gcgctttctg gaggacacat ttggcaatga tgggcgaccc      420

cgtgtggcct ggcacattga ccccttcggc cactctcggg agcaggcctc gctgtttgcg      480

cagatgggct tcgacggctt cttctttggg cgccttgatt atcaagataa gtgggtacgg      540

atgcagaagc tggagatgga gcaggtgtgg cgggccagca ccagcctgaa gcccccgacc      600

gcggacctct tcactggtgt gcttcccaat ggttacaacc cgccaaggaa tctgtgctgg      660

gatgtgctgt gtgtcgatca gccgctggtg gaggaccctc gcagccccga gtacaacgcc      720

aaggagctgg tcgattactt cctaaatgtg gccactgccc agggccggta ttaccgcacc      780

aaccacactg tgatgaccat gggctcggac ttccaatatg agaatgccaa catgtggttc      840

aagaaccttg acaagctcat ccggctggta aatgcgcagc aggcaaaagg aagcagtgtc      900

catgttctct actccacccc cgcttgttac ctctgggagc tgaacaaggc caacctcacc      960

tggtcagtga aacatgacga cttcttccct tacgcggatg gcccccacca gttctggacc     1020

ggttactttt ccagtcggcc ggccctcaaa cgctacgagc gcctcagcta caacttcctg     1080

caggtgtgca accagctgga ggcgctggtg ggcctggcgg ccaacgtggg accctatggc     1140

tccggagaca gtgcacccct caatgaggcg atggctgtgc tccagcatca cgacgccgtc     1200

agcggcacct cccgccagca cgtggccaac gactacgcgc gccagcttgc ggcaggctgg     1260

gggccttgcg aggttcttct gagcaacgcg ctggcgcggc tcagaggctt caaagatcac     1320

ttcacctttt gccaacagct aaacatcagc atctgcccgc tcagccagac ggcggcgcgc     1380

ttccaggtca tcgtttataa tcccctgggg cggaaggtga attggatggt acggctgccg     1440

gtcagcgaag gcgttttcgt tgtgaaggac cccaatggca ggacagtgcc cagcgatgtg     1500

gtaatatttc ccagctcaga cagccaggcg caccctccgg agctgctgtt ctcagcctca     1560

ctgcccgccc tgggcttcag cacctattca gtagcccagg tgcctcgctg gaagccccag     1620

gcccgcgcac cacagcccat ccccagaaga tcctggtccc ctgctttaac catcgaaaat     1680

gagcacatcc gggcaacgtt tgatcctgac acagggctgt tgatggagat tatgaacatg     1740

aatcagcaac tcctgctgcc tgttcgccag accttcttct ggtacaacgc cagtataggt     1800

gacaacgaaa gtgaccaggc ctcaggtgcc tacatcttca gacccaacca acagaaaccg     1860

ctgcctgtga gccgctgggc tcagatccac ctggtgaaga cacccttggt gcaggaggtg     1920

caccagaact tctcagcttg gtgttcccag gtggttcgcc tgtacccagg acagcggcac     1980

ctggagctag agtggtcggt ggggccgata cctgtgggcg acacctgggg gaaggaggtc     2040

atcagccgtt ttgacacacc gctggagaca aagggacgct tctacacaga cagcaatggc     2100

cgggagatcc tggagaggag gcgggattat cgacccacct ggaaactgaa ccagacggag     2160

cccgtggcag gaaactacta tccagtcaac acccggattt acatcacgga tggaaacatg     2220

cagctgactg tgctgactga ccgctcccag gggggcagca gcctgagaga tggctcgctg     2280

gagctcatgg tgcaccgaag gctgctgaag gacgatggac gcggagtatc ggagccacta     2340

atggagaacg ggtcgggggc gtgggtgcga gggcgccacc tggtgctgct ggacacagcc     2400

caggctgcag ccgccggaca ccggctcctg gcggagcagg aggtcctggc ccctcaggtg     2460

gtgctggccc cgggtggcgg cgccgcctac aatctcgggg ctcctccgcg cacgcagttc     2520

tcagggctgc gcagggacct gccgccctcg gtgcacctgc tcacgctggc cagctggggc     2580

cccgaaatgg tgctgctgcg cttggagcac cagtttgccg taggagagga ttccggacgt     2640

aacctgagcg cccccgttac cttgaacttg agggacctgt tctccacctt caccatcacc     2700

cgcctgcagg agaccacgct ggtggccaac cagctccgcg aggcagcctc caggctcaag     2760

tggacaacaa acacaggccc cacaccccac caaactccgt accagctgga cccggccaac     2820

atcacgctgg aacccatgga aatccgcact ttcctggcct cagttcaatg gaaggaggtg     2880

gatggt                                                                2886


<210>  4893
<211>  954
<212>  DNA
<213>  Homo Sapiens

<400>  4893
ctgggcgcaa gcatcatctg taacaagatc ccaggcctgg ctcccagaca gcgggcgatc       60

tgccagagcc ggcccgacgc catcatcgtc ataggagaag gctcacaaat gggcctggac      120

gagtgtcagt ttcagttccg caatggccgc tggaactgct ctgcactggg agagcgcacc      180

gtcttcggga aggagctcaa agtggggagc cgggaggctg cgttcaccta cgccatcatt      240

gccgccggcg tggcccacgc catcacagct gcctgtaccc agggcaacct gagcgactgt      300

ggctgcgaca aagagaagca aggccagtac caccgggacg agggctggaa gtggggtggc      360

tgctctgccg acatccgcta cggcatcggc ttcgccaagg tctttgtgga tgcccgggag      420

atcaagcaga atgcccggac tctcatgaac ttgcacaaca acgaggcagg ccgaaagatc      480

ctggaggaga acatgaagct ggaatgtaag tgccacggcg tgtcaggctc gtgcaccacc      540

aagacgtgct ggaccacact gccacagttt cgggagctgg gctacgtgct caaggacaag      600

tacaacgagg ccgttcacgt ggagcctgtg cgtgccagcc gcaacaagcg gcccaccttc      660

ctgaagatca agaagccact gtcgtaccgc aagcccatgg acacggacct ggtgtacatc      720

gagaagtcgc ccaactactg cgaggaggac ccggtgaccg gcagtgtggg cacccagggc      780

cgcgcctgca acaagacggc tccccaggcc agcggctgtg acctcatgtg ctgtgggcgt      840

ggctacaaca cccaccagta cgcccgcgtg tggcagtgca actgtaagtt ccactggtgc      900

tgctatgtca agtgcaacac gtgcagcgag cgcacggaga tgtacacgtg caag            954


<210>  4894
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4894
atgtggcgcg tgacggcctt catcggcagc aacattgtca cctcgcagac catctgggag       60

ggcctatgga tgaactgcgt ggtgcagagc accggccaga tgcagtgcaa ggtgtacgac      120

tcgctgctgg cactgccgca ggacctgcag gcggcccgc                             159


<210>  4895
<211>  2535
<212>  DNA
<213>  Homo Sapiens

<400>  4895
ttgctggtga tcatgtcact tggattaggc ctggggcttg gactcaggaa actggaaaag       60

caaggcagct gcaggaagaa gtgctttgat gcatcattta gaggactgga gaactgccgg      120

tgtgatgtgg catgtaaaga ccgaggtgat tgctgctggg attttgaaga cacctgtgtg      180

gaatcaactc gaatatggat gtgcaataaa tttcgttgtg gagagaccag attagaggcc      240

agcctttgct cttgttcaga tgactgtttg cagaggaaag attgctgtgc tgactataag      300

agtgtttgcc aaggagaaac ctcatggctg gaagaaaact gtgacacagc ccagcagtct      360

cagtgcccag aagggtttga cctgccacca gttatcttgt tttctatgga tggatttaga      420

gctgaatatt tatacacatg ggatacttta atgccaaata tcaataaact gaaaacatgt      480

ggaattcatt caaaatacat gagagctatg tatcctacca aaaccttccc aaatcattac      540

accattgtca cgggcttgta tccagagtca catggcatca ttgacaataa tatgtatgat      600

gtaaatctca acaagaattt ttcactttct tcaaaggaac aaaataatcc agcctggtgg      660

catgggcaac caatgtggct gacagcaatg tatcaaggtt taaaagccgc tacctacttt      720

tggcccggat cagaagtggc tataaatggc tcctttcctt ccatatacat gccttacaac      780

ggaagtgtcc catttgaaga gaggatttct acactgttaa aatggctgga cctgcccaaa      840

gctgaaagac ccaggtttta taccatgtat tttgaagaac ctgattcctc tggacatgca      900

ggtggaccag tcagtgccag agtaattaaa gccttacagg tagtagatca tgcttttggg      960

atgttgatgg aaggcctgaa gcagcggaat ttgcacaact gtgtcaatat catccttctg     1020

gctgaccatg gaatggacca gacttattgt aacaagatgg aatacatgac tgattatttt     1080

cccagaataa acttcttcta catgtacgaa gggcctgccc cccgcatccg agctcataat     1140

atacctcatg acttttttag ttttaattct gaggaaattg ttagaaacct cagttgccga     1200

aaacctgatc agcatttcaa gccctatttg actcctgatt tgccaaagcg actgcactat     1260

gccaagaacg tcagaatcga caaagttcat ctctttgtgg atcaacagtg gctggctgtt     1320

aggagtaaat caaatacaaa ttgtggagga ggcaaccatg gttataacaa tgagtttagg     1380

agcatggagg ctatctttct ggcacatgga cccagtttta aagagaagac tgaagttgaa     1440

ccatttgaaa atattgaagt ctataaccta atgtgtgatc ttctacgcat tcaaccagca     1500

ccaaacaatg gaacccatgg tagtttaaac catcttctga aggtgccttt ttatgagcca     1560

tcccatgcag aggaggtgtc aaagttttct gtttgtggct ttgctaatcc attgcccaca     1620

gagtctcttg actgtttctg ccctcaccta caaaatagta ctcagctgga acaagtgaat     1680

cagatgctaa atctcaccca agaagaaata acagcaacag tgaaagtaaa tttgccattt     1740

gggaggccta gggtactgca gaagaacgtg gaccactgtc tcctttacca cagggaatat     1800

gtcagtggat ttggaaaagc tatgaggatg cccatgtgga gttcatacac agtcccccag     1860

ttgggagaca catcgcctct gcctcccact gtcccagact gtctgcgggc tgatgtcagg     1920

gttcctcctt ctgagagcca aaaatgttcc ttctatttag cagacaagaa tatcacccac     1980

ggcttcctct atcctcctgc cagcaataga acatcagata gccaatatga tgctttaatt     2040

actagcaatt tggtacctat gtatgaagaa ttcagaaaaa tgtgggacta cttccacagt     2100

gttcttctta taaaacatgc cacagaaaga aatggagtaa atgtggttag tggaccaata     2160

tttgattata attatgatgg ccattttgat gctccagatg aaattaccaa acatttagcc     2220

aacactgatg ttcccatccc aacacactac tttgtggtgc tgaccagttg taaaaacaag     2280

agccacacac cggaaaactg ccctgggtgg ctggatgtcc taccctttat catccctcac     2340

cgacctacca acgtggagag ctgtcctgaa ggtaaaccag aagctctttg ggttgaagaa     2400

agatttacag ctcacattgc ccgggtccgt gatgtagaac ttctcactgg gcttgacttc     2460

tatcaggata aagtgcagcc tgtctctgaa attttgcaac taaagacata tttaccaaca     2520

tttgaaacca ctatt                                                      2535


<210>  4896
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  4896
gtggagccca tcagcctggg actggccctg gccggcgtcc tcaccggcta catctacccg       60

cgtctctact gcctcttcgc cgagtgctgc gggcagaagc ggagccttag ccgggaggca      120

ctgcagaagg atctggacga caacctcttt ggacagcatc ttgcaaagaa aatcatctta      180

aatgccgtgt ttggtttcat aaacaaccca aagcccaaga aacctctcac gctctccctg      240

cacgggtgga caggcaccgg caaaaatttc gtcagcaaga tcatcgcaga gaatatttac      300

gagggtggtc tgaacagtga ctatgtccac ctgtttgtgg ccacattgca ctttccacat      360

gcttcaaaca tcaccttgta caaggatcag ttacagttgt ggattcgagg caacgtgagt      420

gcctgtgcga ggtccatctt catatttgat gaaatggata agatgcatgc aggcctcata      480

gatgccatca agcctttcct cgactattat gacctggtgg atggggtctc ctaccagaaa      540

gccatgttca tatttctcag caatgctgga gcagaaagga tcacagatgt ggctttggat      600

ttctggagga gtggaaagca gagggaagac atcaagctca aagacattga acacgcgttg      660

tctgtgtcgg ttttcaataa caagaacagt ggcttctggc acagcagctt aattcaccgg      720

aacctcattg attattttgt tcccttcctc cccctggaat acaaacacct aaaaatgtgt      780

atccgagtgg aaatgcagtc ccgaggctat gaaattgatg aagacattgt aagcagagtg      840

gctgaggaga tgacattttt ccccaaagag gagagagttt tctcagataa aggctgcaaa      900

acggtgttca ccaagttaga ttattactac gatgat                                936


<210>  4897
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  4897
ttcgagccca tcaccgtggg cctagccatc ggggccgcgt cggccatcac cggctacctg       60

tcctacaatg acatctactg ccgcttcgcc gagtgctgcc gcgaggagcg gccgctcaac      120

gcttcggctc tcaagctgga tttggaggag aagctgtttg gacagcatct agccacggaa      180

gtgattttca aggcgctgac tggcttcagg aacaacaaaa atcccaagaa accactgacc      240

ctttccttac acggctgggc tggcacaggc aagaattttg tcagtcaaat tgtggctgaa      300

aatcttcacc caaaaggtct gaagagtaac tttgtccacc tgtttgtatc gactctgcac      360

ttccctcatg agcagaagat aaaactgtac caggaccagt tacagaagtg gatccgcggt      420

aatgtgagtg catgtgcgaa ctctgttttc atatttgacg agatggataa attgcacccc      480

gggatcattg acgcaatcaa gccgtttcta gactactacg agcaggttga cggagtgtct      540

taccgcaaag ccatcttcat ctttctcagc aatgcaggcg gggaccttat aactaagacg      600

gctcttgact tttggcgggc cggaagaaag agggaagaca ttcagctgaa ggacctggaa      660

cctgtactgt ctgtcggagt cttcaataat aaacacagtg gcctgtggca cagtggactg      720

atcgacaaaa acctcattga ttactttatc cccttcctgc ctttggagta cagacatgtg      780

aaaatgtgtg tgagggccga gatgagggcc cgtggttctg ccatagatga agacattgtc      840

acaagagtgg cagaggaaat gacgtttttc cccagagacg agaaaatcta ctcagacaag      900

ggctgcaaga ctgtgcagtc gcggctggat ttccac                                936


<210>  4898
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  4898
gctaatgggt tttttgaaga aataagacag ggcaacattg agcgtgagtg caaagaagaa       60

ttctgtacat ttgaagaagc aagagaagct tttgaaaata atgaaaaaac taaggagttt      120

tggagcacct acacaaaagc gcaacaaggg gagagtaacc gaggaagtga ctggtttcag      180

ttttacctt                                                              189


<210>  4899
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  4899
taccgggaga ggcaggtggt gagccacctc caagacaagt atgtctttat cacgggctgt       60

gactcgggct ttgggaacct gctggccaga cagctggatg cacgaggctt gagagtgctg      120

gctgcgtgtc tgacggagaa gggggccgag cagctgaggg gccagacgtc tgacaggctg      180

gagacggtga ccctggatgt taccaagatg gagagcatcg ctgcagctac tcagtgggtg      240

aaggagcatg tgggggacag aggactctgg ggactggtga acaatgcagg cattcttaca      300

ccaattacct tatgtgagtg gctgaacact gaggactcta tgaatatgct caaagtgaac      360

ctcattggtg tgatccaggt gaccttgagc atgcttcctt tggtgaggag agcacgggga      420

agaattgtca atgtctccag cattctggga agagttgctt tctttgtagg aggctactgt      480

gtctccaagt atggagtgga agccttttca gatattctga ggcgtgagat tcaacatttt      540

ggggtgaaaa tcagcatagt tgaacctggc tacttcagaa cgggaatgac aaacatgaca      600

cagtccttag agcgaatgaa gcaaagttgg aaagaagccc ccaagcatat taaggagacc      660

tatggacagc agtattttga tgccctttac aatatcatga aggaagggct gttgaattgt      720

agcacaaacc tgaacctggt cactgactgc atggaacatg ctctgacatc ggtgcatccg      780

cgaactcgat attcagctgg ctgggatgct aaatttttct tcatccctct atcttattta      840

cctacatcac tggcagacta cattttgact agatcttggc ccaaaccagc ccaggcagtc      900


<210>  4900
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  4900
cagcagctcc gcggcaccag agcgatgaat gacatcggcg actacgtggg ctccaacctg       60

gagatctcct ggctccccaa cctggacggg ctgatagccg gctacgcccg caacttccgg      120

cctggcatcg gaggcccccc cgtgaatgtg gcccttgccc tggaggtggc cagcatcgac      180

cacatctcag aggccaacat ggagtacacc atgacggtgt tcctgcacca gagctggcgg      240

gacagcaggc tctcctacaa ccacaccaac gagaccctgg gcctggacag ccgcttcgtg      300

gacaagctgt ggctgcccga caccttcatc gtgaacgcca agtcggcctg gttccacgac      360

gtgacggtgg agaacaagct catccggctg cagcccgacg gcgtgatcct gtacagcatc      420

cgaatcacct ccactgtggc ctgcgacatg gacctggcca aataccccat ggacgagcag      480

gagtgcatgc tggacctgga gagctacggt tactcatcgg aggacatcgt ctactactgg      540

tcggagagcc aggagcacat ccacgggctg gacaagctgc agctggcgca gttcaccatc      600

accagctacc gcttcaccac ggagctgatg aacttcaagt ccgctggcca gttcccacgg      660

ctcagcctgc acttccacct gcggaggaac cgcggc                                696


<210>  4901
<211>  1104
<212>  DNA
<213>  Homo Sapiens

<400>  4901
ctgcatctgg gggtaacccc ctctgtgatc cgtaagcgat acaacttgac ctcacaagac       60

gtgggctctg gcaccagcaa taacagccaa gcctgtgccc agttcctgga gcagtatttc      120

catgactcag acctggctca gttcatgcgc ctcttcggtg gcaactttgc acatcaggca      180

tcagtagccc gtgtggttgg acaacagggc cggggccggg ccgggattga ggccagtcta      240

gatgtgcagt acctgatgag tgctggtgcc aacatctcca cctgggtcta cagtagccct      300

ggccggcatg agggacagga gcccttcctg cagtggctca tgctgctcag taatgagtca      360

gccctgccac atgtgcatac tgtgagctat ggagatgatg aggactccct cagcagcgcc      420

tacatccagc gggtcaacac tgagctcatg aaggctgccg ctcggggtct caccctgctc      480

ttcgcctcag gtgacagtgg ggccgggtgt tggtctgtct ctggaagaca cgagttccgc      540

cctaccttcc ctgcctccag cccctatgtc accacagtgg gaggcacatc cttccaggaa      600

cctttcctca tcacaaatga aattgttgac tatatcagtg gtggtggctt cagcaatgtg      660

ttcccacggc cttcatacca ggaggaagct gtaacgaagt tcctgagctc tagcccccac      720

ctgccaccat ccagttactt caatgccagt ggccgtgcct acccagatgt ggctgcactt      780

tctgatggct actgggtggt cagcaacaga gtgcccattc catgggtgtc cggaacctcg      840

gcctctactc cagtgtttgg ggggatccta tccttgatca atgagcacag gatccttagt      900

ggccgccccc ctcttggctt tctcaaccca aggctctacc agcagcatgg ggcaggactc      960

tttgatgtaa cccgtggctg ccatgagtcc tgtctggatg aagaggtaga gggccagggt     1020

ttctgctctg gtcctggctg ggatcctgta acaggctggg gaacacccaa cttcccagct     1080

ttgctgaaga ctctactcaa cccc                                            1104


<210>  4902
<211>  1113
<212>  DNA
<213>  Homo Sapiens

<400>  4902
gaggaagctg gagcgagggt gcaacaaaac gttccaagtg ggacagatac tggagatcct       60

caaagtaagc ccctcggtga ctgggctgct ggcaccatgg acccagagag cagtatcttt      120

attgaggatg ccattaagta tttcaaggaa aaagtgagca cacagaatct gctactcctg      180

ctgactgata atgaggcctg gaacggattc gtggctgctg ctgaactgcc caggaatgag      240

gcagatgagc tccgtaaagc tctggacaac cttgcaagac aaatgatcat gaaagacaaa      300

aactggcacg ataaaggcca gcagtacaga aactggtttc tgaaagagtt tcctcggttg      360

aaaagtgagc ttgaggataa cataagaagg ctccgtgccc ttgcagatgg ggttcagaag      420

gtccacaaag gcaccaccat cgccaatgtg gtgtctggct ctctcagcat ttcctctggc      480

atcctgaccc tcgtcggcat gggtctggca cccttcacag agggaggcag ccttgtactc      540

ttggaacctg ggatggagtt gggaatcaca gccgctttga ccgggattac cagcagtacc      600

atggactacg gaaagaagtg gtggacacaa gcccaagccc acgacctggt catcaaaagc      660

cttgacaaat tgaaggaggt gagggagttt ttgggtgaga acatatccaa ctttctttcc      720

ttagctggca atacttacca actcacacga ggcattggga aggacatccg tgccctcaga      780

cgagccagag ccaatcttca gtcagtaccg catgcctcag cctcacgccc ccgggtcact      840

gagccaatct cagctgaaag cggtgaacag gtggagaggg ttaatgaacc cagcatcctg      900

gaaatgagca gaggagtcaa gctcacggat gtggcccctg taagcttctt tcttgtgctg      960

gatgtagtct acctcgtgta cgaatcaaag cacttacatg agggggcaaa gtcagagaca     1020

gctgaggagc tgaagaaggt ggctcaggag ctggaggaga agctaaacat tctcaacaat     1080

aattataaga ttctgcaggc ggaccaagaa ctg                                  1113


<210>  4903
<211>  861
<212>  DNA
<213>  Homo Sapiens

<400>  4903
cgcaccgccg agctaggcca gcaggagctt ctgcggaaag cggggaccct ccaggatgac       60

gtccgcgatg gcgtggcccc aaacggctct gcccagcagt tgccgcagac catcatcatc      120

ggcgtgcgca agggcggcac gcgcgcactg ctggagatgc tcagcctgca ccccgacgtg      180

gcggccgcgg agaacgaggt ccacttcttc gactgggagg agcattacag ccacggcttg      240

ggctggtacc tcagccagat gcccttctcc tggccacacc agctcacagt ggagaagacc      300

cccgcgtatt tcacgtcgcc caaagtgcct gagcgagtct acagcatgaa cccgtccatc      360

cggctgctgc tcatcctgcg agacccgtcg gagcgcgtgc tatctgacta cacccaagtg      420

ttctacaacc acatgcagaa gcacaagccc tacccgtcca tcgaggagtt cctggtgcgc      480

gatggcaggc tcaatgtgga ctacaaggcc ctcaaccgca gcctctacca cgtgcacatg      540

cagaactggc tgcgcttttt cccgctgcgc cacatccaca ttgtggacgg cgaccgcctc      600

atcagggacc ccttccctga gatccaaaag gtcgagaggt tcctaaagct gtcgccgcag      660

atcaatgctt cgaacttcta ctttaacaaa accaagggct tttactgcct gcgggacagc      720

ggccgggacc gctgcttaca tgagtccaaa ggccgggcgc acccccaagt cgatcccaaa      780

ctactcaata aactgcacga atattttcat gagccaaata agaagttctt cgagcttgtt      840

ggcagaacat ttgactggca c                                                861


<210>  4904
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  4904
tacttcgggc tgacgggcag cgagcccctg accatcctcc cgctgaccct ggagccagag       60

gcggccgccc aggcgcacta caaggcctgc gaccggctga agctggagcg gaagcagcgg      120

cgcatgtgcc gccgggaccc gggcgtggca gagacgctgg tggaggccgt gagcatgagt      180

gcgctcgagt gccagttcca gttccgcttt gagcgctgga actgcacgct ggagggccgc      240

taccgggcca gcctgctcaa gcgaggcttc aaggagactg ccttcctcta tgccatctcc      300

tcggctggcc tgacgcacgc actggccaag gcgtgcagcg cgggccgcat ggagcgctgt      360

acctgcgatg aggcacccga cctggagaac cgtgaggcct ggcagtgggg gggctgcgga      420

gacaacctta agtacagcag caagttcgtc aaggaattcc tgggcagacg gtcaagcaag      480

gatctgcgag cccgtgtgga cttccacaac aacctcgtgg gtgtgaaggt gatcaaggct      540

ggggtggaga ccacctgcaa gtgccacggc gtgtcaggct catgcacggt gcggacctgc      600

tggcggcagt tggcgccttt ccatgaggtg ggcaagcatc tgaagcacaa gtatgagacg      660

gcactcaagg tgggcagcac caccaatgaa gctgccggcg aggcgggtgc catctcccca      720

ccacggggcc gtgcctcggg ggcaggtggc agcgacccgc tgccccgcac tccagagctg      780

gtgcacctgg atgactcgcc tagcttctgc ctggctggcc gcttctcccc gggcaccgct      840

ggccgtaggt gccaccgtga gaagaactgc gagagcatct gctgtggccg cggccataac      900

acacagagcc gggtggtgac aaggccctgc cagtgccagg tgcgttggtg ctgctatgtg      960

gagtgcaggc agtgcacgca gcgtgaggag gtctacacct gcaagggc                  1008


<210>  4905
<211>  1140
<212>  DNA
<213>  Homo Sapiens

<400>  4905
gaagaggggc ttaatttccc cacatatgat gggaaggacc gagtggtaag tctttccgag       60

aagaacttca agcaggtttt aaagaaatat gacttgcttt gcctctacta ccatgagccg      120

gtgtcttcag ataaggtcac gcaaaaacag ttccaactga aagaaatcgt gcttgagctt      180

gtggcccagg tccttgaaca taaagctata ggctttgtga tggtggatgc caagaaagaa      240

gccaagcttg ccaagaaact gggttttgat gaagaaggaa gcctgtatat tcttaagggt      300

gatcgcacaa tagagtttga tggcgagttt gcagctgatg tcttggtgga gttcctcttg      360

gatctaattg aagacccagt ggagatcatc agcagcaaac tggaagtcca agccttcgaa      420

cgcattgaag actacatcaa actcattggc tttttcaaga gtgaggactc agaatactac      480

aaggcttttg aagaagcagc tgaacacttc cagccttaca tcaaattctt tgccaccttt      540

gacaaagggg ttgcaaagaa attatctttg aagatgaatg aggttgactt ctatgagcca      600

tttatggatg agcccattgc catccccaac aaaccttaca cagaagagga gctggtggag      660

tttgtgaagg aacaccaaag acccactcta cgtcgcctgc gcccagaaga aatgtttgaa      720

acatgggaag atgatttgaa tgggatccac attgtggcct ttgcagagaa gagtgatcca      780

gatggctacg aattcctgga gatcctgaaa caggttgccc gggacaatac tgacaacccc      840

gatctgagca tcctgtggat cgacccggac gactttcctc tgctcgttgc ctactgggag      900

aagactttca agattgacct attcaggcca cagattgggg tggtgaatgt cacagatgct      960

gacagtgtct ggatggagat tccagatgat gacgatcttc caactgctga ggagctggag     1020

gactggattg aggatgtgct ttctggaaag ataaacactg aagatgatga tgaagatgat     1080

gatgatgatg ataattctga tgaagaggat aatgatgaca gtgatgatga tgatgatgaa     1140


<210>  4906
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  4906
gggccatggg ctaatatatg tgctggcaag tcttccaatg agatccggac gtgtgaccgc       60

catggctgtg gacagtactc tgctcaaaga agtcagaggc ctcaccaggg tgtggacgtc      120

ttgtgctctg ctggatctac tgtgtacgca ccattcactg gaatgattgt gggccaggag      180

aaaccttatc aaaacaagaa tgctatcaat aatggtgttc gaatatctgg aagaggtttt      240

tgtgtcaaaa tgttctacat taagccaatt aagtataaag gtcctattaa gaagggagaa      300

aaacttggaa ctctattgcc cttgcagaaa gtttatcctg gcatacaatc gcatgtgcac      360

attgaaaact gtgactcgag tgaccctact gcatacctg                             399


<210>  4907
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  4907
cgccacggcg gccggacggt ggagaacatg agcatcatcg gctggttcgt gcgaagcttc       60

aagtactttt acgggctccg cttcgaggtg cgggacccgc gcaggctgca ggaggcccgt      120

ccctgtgtca tcgtctccaa ccaccagagc atcctggaca tgatgggcct catggaggtc      180

cttccggagc gctgcgtgca gatcgccaag cgg                                   213


<210>  4908
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  4908
ggtttcacac ctgaccacca ctgccagagt cctggggtgg ctgagctgag ccagcgctgt       60

ggctggagcc ctgcggagga gctgaactat acagtgccag gcctggggcc cgcgggcgag      120

gccttccttg gccagtgcag gcgctatgaa gtggactgga accagagcgc cctcagctgt      180

gtagaccccc tggctagcct ggccaccaac aggagccacc tgccgctggg tccctgccag      240

gatggctggg tgtatgacac gcccggctct tccatcgtca ctgagttcaa cctggtgtgt      300

gctgactcct ggaagctgga c                                                321


<210>  4909
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  4909
ccaggggtgg aaggcgtgac acactacaag gccggcgacc ctgttattct gtatgtcaac       60

aaagtgggac cctaccataa ccctcaggaa acttaccact actatcagct tccagtctgc      120

tgccctgaga agatacgtca caaaagcctt agcctgggtg aagtgctgga tggggaccga      180

atggctgagt ctttgtatga gatccgcttt cgggaaaacg tggagaagag aattctgtgc      240

cacatgcagc tcagttctgc acaggtggag cagctgcgcc aggccattga agaactgtac      300

tactttgaat ttgtggtaga tgacttgcca atccggggct ttgtgggcta catggaggag      360

agtggtttcc tgccacacag ccacaagata ggactctgga cccatttgga cttccaccta      420

gaattccatg gagaccgaat tatatttgcc aatgtttcag tgcgggacgt caagccccac      480

agcttggatg ggttacgacc tgacgagttc ctaggcctta cccacactta tagcgtgcgc      540

tggtctgaga cttcagtgga gcgtcggagt gacaggcgcc gtggtgacga tggtggtttc      600

tttcctcgaa cactggaaat ccattgg                                          627


<210>  4910
<211>  1161
<212>  DNA
<213>  Homo Sapiens

<400>  4910
tggaagttca tgggcagcaa gtgctccaac tctgggatag agtgcgactc ctcaggtacc       60

tgcatcaacc cctctaactg gtgtgatggc gtgtcacact gccccggcgg ggaggacgag      120

aatcggtgtg ttcgcctcta cggaccaaac ttcatccttc aggtgtactc atctcagagg      180

aagtcctggc accctgtgtg ccaagacgac tggaacgaga actacgggcg ggcggcctgc      240

agggacatgg gctataagaa taatttttac tctagccaag gaatagtgga tgacagcgga      300

tccaccagct ttatgaaact gaacacaagt gccggcaatg tcgatatcta taaaaaactg      360

taccacagtg atgcctgttc ttcaaaagca gtggtttctt tacgctgtat agcctgcggg      420

gtcaacttga actcaagccg ccagagcagg atcgtgggcg gcgagagcgc gctcccgggg      480

gcctggccct ggcaggtcag cctgcacgtc cagaacgtcc acgtgtgcgg aggctccatc      540

atcacccccg agtggatcgt gacagccgcc cactgcgtgg aaaaacctct taacaatcca      600

tggcattgga cggcatttgc ggggattttg agacaatctt tcatgttcta tggagccgga      660

taccaagtag aaaaagtgat ttctcatcca aattatgact ccaagaccaa gaacaatgac      720

attgcgctga tgaagctgca gaagcctctg actttcaacg acctagtgaa accagtgtgt      780

ctgcccaacc caggcatgat gctgcagcca gaacagctct gctggatttc cgggtggggg      840

gccaccgagg agaaagggaa gacctcagaa gtgctgaacg ctgccaaggt gcttctcatt      900

gagacacaga gatgcaacag cagatatgtc tatgacaacc tgatcacacc agccatgatc      960

tgtgccggct tcctgcaggg gaacgtcgat tcttgccagg gtgacagtgg agggcctctg     1020

gtcacttcga agaacaatat ctggtggctg ataggggata caagctgggg ttctggctgt     1080

gccaaagctt acagaccagg agtgtacggg aatgtgatgg tattcacgga ctggatttat     1140

cgacaaatga gggcagacgg c                                               1161


<210>  4911
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  4911
atggatcatt cccaccatat ggggatgagc tatatggact ccaacagtac catgcaacct       60

tctcaccatc acccaaccac ttcagcctca cactcccatg gtggaggaga cagcagcatg      120

atgatgatgc ctatgacctt ctactttggc tttaagaatg tggaactact gttttccggt      180

ttg                                                                    183


<210>  4912
<211>  1536
<212>  DNA
<213>  Homo Sapiens

<400>  4912
gaattcttca cctctattgg gcacatgact gacctgattt atgcagagaa agagctggtg       60

cagtctctga aagagtacat ccttgtggag gaagccaagc tttccaagat taagagctgg      120

gccaacaaaa tggaagcctt gactagcaag tcagctgctg atgctgaggg ctacctggct      180

caccctgtga atgcctacaa actggtgaag cggctaaaca cagactggcc tgcgctggag      240

gaccttgtcc tgcaggactc agctgcaggt tttatcgcca acctctctgt gcagcggcag      300

ttcttcccca ctgatgagga cgagatagga gctgccaaag ccctgatgag acttcaggac      360

acatacaggc tggacccagg cacaatttcc agaggggaac ttccaggaac caagtaccag      420

gcaatgctga gtgtggatga ctgctttggg atgggccgct cggcctacaa tgaaggggac      480

tattatcata cggtgttgtg gatggagcag gtgctaaagc agcttgatgc cggggaggag      540

gccaccacaa ccaagtcaca ggtgctggac tacctcagct atgctgtctt ccagttgggt      600

gatctgcacc gtgccctgga gctcacccgc cgcctgctct cccttgaccc aagccacgaa      660

cgagctggag ggaatctgcg gtactttgag cagttattgg aggaagagag agaaaaaacg      720

ttaacaaatc agacagaagc tgagctagca accccagaag gcatctatga gaggcctgtg      780

gactacctgc ctgagaggga tgtttacgag agcctctgtc gtggggaggg tgtcaaactg      840

acaccccgta gacagaagag gcttttctgt aggtaccacc atggcaacag ggccccacag      900

ctgctcattg cccccttcaa agaggaggac gagtgggaca gcccgcacat cgtcaggtac      960

tacgatgtca tgtctgatga ggaaatcgag aggatcaagg agatcgcaaa acctaaactt     1020

gcacgagcca ccgttcgtga tcccaagaca ggagtcctca ctgtcgccag ctaccgggtt     1080

tccaaaagct cctggctaga ggaagatgat gaccctgttg tggcccgagt aaatcgtcgg     1140

atgcagcata tcacagggtt aacagtaaag actgcagaat tgttacaggt tgcaaattat     1200

ggagtgggag gacagtatga accgcacttc gacttctcta ggcgaccttt tgacagcggc     1260

ctcaaaacag aggggaatag gttagcgacg tttcttaact acatgagtga tgtagaagct     1320

ggtggtgcca ccgtcttccc tgatctgggg gctgcaattt ggcctaagaa gggtacagct     1380

gtgttctggt acaacctctt gcggagcggg gaaggtgact accgaacaag acatgctgcc     1440

tgccctgtgc ttgtgggctg caagtgggtc tccaataagt ggttccatga acgaggacag     1500

gagttcttga gaccttgtgg atcaacagaa gttgac                               1536


<210>  4913
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  4913
gggatcctgg aactggcagg aactgtgggt tgtgttggtc cccgaacccc catcgcctat       60

atgaaatatg gttgcttttg tggcttggga ggccatggcc agccccgcga tgccattgac      120

tggtgctgcc atggccacga ctgttgttac actcgagctg aggaggccgg ctgcagcccc      180

aagacagagc gctactcctg gcagtgcgtc aatcagagcg tcctgtgcgg accggcagag      240

aacaaatgcc aagaactgtt gtgcaagtgt gaccaggaga ttgctaactg cttagcccaa      300

actgagtaca acttaaagta cctcttctac ccccagttcc tatgtgagcc ggactcgccc      360

aagtgtgac                                                              369


<210>  4914
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  4914
tctaccgagg atgaaggcga ggacccctgg taccaaaaag catgcaagtg cgattgccaa       60

ggaggaccca atgctctgtg gtctgcaggt gccacctcct tggactgtat accagaatgc      120

ccatatcaca agcctctggg tttcgagtca ggggaggtca caccggacca gatcacctgc      180

tctaacccgg agcagtatgt gggctggtat tcttcgtgga ctgcaaacaa ggcccggctc      240

aacagtcaag gctttgggtg tgcctggctc tccaagttcc aggacagtag ccagtggtta      300

cagatagatc tgaaggagat caaagtgatt tcagggatcc tcacccaggg gcgctgtgac      360

atcgatgagt ggatgaccaa gtacagcgtg cagtacagga ccgatgagcg cctgaactgg      420

atttactaca aggaccagac tggaaacaac cgggtcttct atggcaactc ggaccgcacc      480

tccacggttc agaacctgct gcggcccccc atcatctccc gcttcatccg cctcatcccg      540

ctgggctggc acgtccgcat tgccatccgg atggagctgc tggagtgcgt cagcaagtgt      600

gcc                                                                    603


<210>  4915
<211>  819
<212>  DNA
<213>  Homo Sapiens

<400>  4915
aaaaaaggct accaggagcg ggacctggaa ccccagtttt ccatcatcac caaactcaaa       60

ggggtttccg tcactcagat caaggagctt ggaaaccggc tgtgggatgt ggccgacttc      120

gtgaagccac ctcagggaga gaacgtgttc ttcttggtga ccaacttcct tgtgacgcca      180

gcccaagttc agggcagatg cccagagcac ccgtccgtcc cactggctaa ctgctgggtc      240

gacgaggact gccccgaagg ggagggaggc acacacagcc acggtgtaaa aacaggccag      300

tgtgtggtgt tcaatgggac ccacaggacc tgtgagatct ggagttggtg ccccgtggag      360

agtggcgttg tgccctcgag gcccctgctg gcccaggccc agaacttcac actgttcatc      420

aaaaacacag tcaccttcag caagttcaac ttctctaagt ccaatgcctt ggagacctgg      480

gaccccacct attttaagca ctgccgctat gaaccacaat tcagccccta ctgtcccgtg      540

ttccgcattg gggacctcgt ggccaaggct ggagggacct tcgaggacct ggcgttgctg      600

ggtggctctg taggcatcag agttcactgg gattgtgacc tggacaccgg ggactctggc      660

tgctggcctc actactcctt ccagctgcag gagaagagct acaacttcag gacagccact      720

cactggtggg agcaaccggg tgtggaggcc cgcaccctgc tcaagctcta tggaatccgc      780

ttcgacatcc tcgtcaccgg gcaggcaggg aagttcggg                             819


<210>  4916
<211>  153
<212>  DNA
<213>  Homo Sapiens

<400>  4916
cgcgtgtcgg ccttcatcgg cagcaacatc atcacgtcgc agaacatctg ggagggcctg       60

tggatgaact gcgtggtgca gagcaccggc cagatgcagt gcaaggtgta cgactcgctg      120

ctggcactgc cacaggacct tcaggcggcc cgc                                   153


<210>  4917
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  4917
gcagaggcgg cgctgctccc ccaaaacgac acgcgcttgg accccgaagc ctatggcgcc       60

ccgtgcgcgc gcggctcgca gccctggcag gtctcgctct tcaacggcct ctcgttccac      120

tgcgcgggtg tcctggtgga ccagagttgg gtgctgacgg ccgcgcactg cggaaacaag      180

ccactgtggg ctcgagtagg ggatgaccac ctgctgcttc ttcagggcga gcagctccgc      240

cggacgactc gctctgttgt ccatcccaag taccaccagg gctcaggccc catcctgcca      300

aggcgaacgg atgagcacga tctcatgttg ctaaagctgg ccaggcccgt agtgccgggg      360

ccccgcgtcc gggccctgca gcttccctac cgctgtgctc agcccggaga ccagtgccag      420

gttgctggct ggggcaccac ggccgcccgg agagtgaagt acaacaaggg cctgacctgc      480

tccagcatca ctatcctgag ccctaaagag tgtgaggtct tctaccctgg cgtggtcacc      540

aacaacatga tatgtgctgg actggaccgg ggccaggacc cttgccagag tgactctgga      600

ggccccctgg tctgtgacga gaccctccaa ggcatcctct cgtggggtgt ttacccctgt      660

ggctctgccc agcatccagc tgtctacacc cagatctgca aatacatgtc ctggatcaat      720

aaagtcatac gctccaac                                                    738


<210>  4918
<211>  1506
<212>  DNA
<213>  Homo Sapiens

<400>  4918
ctacccccac cctgtgagag tgagatttac tgccacgggg agctcctaaa ccaagttcaa       60

atggccaagc tctaccagga tgacaagcag tttgtggaca tgccactgtc tatagctcca      120

gaacaagtcc tgcagacctt cactgagctg tccagggacc acaatcacag catccccagg      180

gagcagctgc aggcgtttgt ccacgaacac ttccaggcca aggggcagga gctgcagccc      240

tggacccctg cagactggaa agacagcccc cagttcctgc agaagatttc agatgccaaa      300

ctgcgtgcct gggcagggca gctgcatcag ctctggaaga agctggggaa gaagatgaag      360

ccagaggttc tcagccaccc tgagcggttc tctctcatct actcagaaca tcccttcatt      420

gtgcctggcg gtcgctttgt tgagttctac tactgctatg ggcatgtccc caatggtggg      480

cgcgtgtact acctgcagcg gagccagccc ccactcttga ccctcatgat ggattgctac      540

ttgactcaca ccaatgacac cgcctttcta caggaaaaca ttgaaacact agccttggaa      600

ttggactttt ggaccaagaa caggactgtc tctgtgagct tggagggaaa gaactacctc      660

ctgaatcgct attatgtccc ttatggggga cccaggcctg agtcctacag caaagatgtg      720

gagttggctg acaccttgcc agaaggagac cgggaggctc tgtgggctga gctcaaggct      780

ggggctgagt ctggctggga cttctcttca cgctggctca ttggaggccc aaaccccaac      840

tcgcttagcg gcatccgaac aagcaaactg gtgcctgttg acctgaatgc cttcctatgc      900

caagcagagg agctgatgag caacttctat tccaggctgg ggaacgactc ccaggccacg      960

aagtacagaa tcctgcggtc gcagcgcttg gccgccctga acacagtcct gtgggatgag     1020

cagaccggag cctggttcga ttacgacctt gagaagaaga agaaaaaccg ggagttttac     1080

ccatccaacc tcactccact ctgggccggg tgtttctctg accctggcgt ggcggacaag     1140

gctctgaaat acctggagga caaccggatc ctgacttacc agtatgggat cccgacctct     1200

ctccagaaga caggccagca gtgggatttc cccaatgcct gggcccccct gcaggacctg     1260

gtcatcagag gcctggccaa ggcaccttta cgtcgggccc aggaagtggc tttccagctg     1320

gctcagaatt ggatccgaac caattttgat gtctactcgc agaagtcagc catgtatgag     1380

aagtatgacg tcagcaacgg tggacagccc ggtgggggag gagaatatga agttcaggag     1440

ggatttggct ggacgaatgg cgtggtcctg atgctgctgg accgctatgg tgaccggctg     1500

acctca                                                                1506


<210>  4919
<211>  510
<212>  DNA
<213>  Homo Sapiens

<400>  4919
gccgaccgag aacgcagcat ccacgacttc tgcctggtgt cgaaggtggt gggcagatgc       60

cgggcctcca tgcctaggtg gtggtacaat gtcactgacg gatcctgcca gctgtttgtg      120

tatgggggct gtgacggaaa cagcaataat tacctgacca aggaggagtg cctcaagaaa      180

tgtgccactg tcacagagaa tgccacgggt gacctggcca ccagcaggaa tgcagcggat      240

tcctctgtcc caagtgctcc cagaaggcag gattctgaag accactccag cgatatgttc      300

aactatgaag aatactgcac cgccaacgca gtcactgggc cttgccgtgc atccttccca      360

cgctggtact ttgacgtgga gaggaactcc tgcaataact tcatctatgg aggctgccgg      420

ggcaataaga acagctaccg ctctgaggag gcctgcatgc tccgctgctt ccgccagcag      480

gagaatcctc ccctgcccct tggctcaaag                                       510


<210>  4920
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  4920
tgcgggccgg gccgggggcc ggttggccgg cgccgctatg cgcgcaagca gctcgtgccg       60

ctactctaca agcaatttgt gcccggcgtg ccagagcgga ccctgggcgc cagtgggcca      120

gcggagggga gggtggcaag gggctccgag cgcttccggg acctcgtgcc caactacaac      180

cccgacatca tcttcaagga tgaggagaac agtggagccg accgcctgat gaccgagcgt      240

tgtaaggagc gggtgaacgc tttggccatt gccgtgatga acatgtggcc cggagtgcgc      300

ctacgagtga ctgagggctg ggacgaggac ggccaccacg ctcaggattc actccactac      360

gaaggccgtg ctttggacat cactacgtct gaccgcgacc gcaacaagta tgggttgctg      420

gcgcgcctcg cagtggaagc cggcttcgac tgggtctact acgagtcccg caaccacgtc      480

cacgtgtcgg tcaaagctga taactcactg gcggtccggg cgggcggc                   528


<210>  4921
<211>  1080
<212>  DNA
<213>  Homo Sapiens

<400>  4921
gccaccgaaa gcgtcaagca agaagatgct ggagtacggc cttctgcagg aaacgtctcc       60

acccacccca gcttgagcca acggcctgga ggctctacca agtcgcatcc ggagccgcag      120

actccaaaag acagccctag caagtcgagt gcggaggcgc agaccccaga agacaccccc      180

aacaagtcgg gtgcggaggc aaagacccaa aaagacagct ccaacaagtc gggtgcggag      240

gcaaagaccc aaaaaggcag cactagcaag tcgggttcgg aggcgcagac cacaaaagac      300

agcactagta agtcgcatcc ggagctgcag actccaaaag acagcactgg caaatcgggt      360

gcggaggcgc agaccccaga agacagcccc aacaggtcgg gtgcggaggc aaagacccaa      420

aaagacagcc ctagcaagtc aggttcggag gcgcagacca caaaagatgt ccctaataag      480

tcgggtgcgg acggccagac cccaaaagac ggctccagca agtcgggtgc ggaggatcag      540

accccaaaag acgtccctaa caagtcgggt gcggagaagc agactccaaa agacggctct      600

aacaagtccg gtgcagagga gcagggccca atagacgggc ccagcaagtc gggtgcggag      660

gagcagacct caaaagacag ccctaacaag gtggttccag agcagccttc ccggaaagac      720

cattccaagc ccatctccaa cccttctgat aacaaggagc tccccaaggc tgacacaaac      780

cagcttgctg acaaagggaa gctttctcct catgctttca aaaccgaatc tggggaggaa      840

actgacctca tttctccccc gcaggaggaa gttaagtctt cagagcctac tgaggatgtg      900

gagcccaaag aggctgaaga tgatgataca ggacccgagg agggctcacc gcccaaagaa      960

gagaaagaaa agatgtccgg ttctgcctcc agtgagaacc gtgaagggac actttcggat     1020

tccacgggta gcgagaagga tgacctttat ccgaacggtt ctggaaatgg cagcgcggag     1080


<210>  4922
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  4922
cagcactggt cccatggctg gtaccctgga ggaaagcgag ccctcagctc agcccaggat       60

ccccagaatg cccttaggcc cccaggaagg gccctggaca ctgcagcagg cagcccagtc      120

cagactgccc atggcctccc aagtgatgcc ctggctcccc tggacgacag catgccctgg      180

gagggcagga ccacggccca gtggtccctt cacaggaagc gacacctggc acggacactg      240

ctgaccgcag cccgagagcc ccgccccgcc ccgccatcct ccaataaagt g               291


<210>  4923
<211>  951
<212>  DNA
<213>  Homo Sapiens

<400>  4923
atgcaattgc cccggtggtg ggagctggga gacccctgtg cttggacggg acagggtcgg       60

gggacacgca ggatgagccc cgcgaccact ggcacattct tgctgacagt gtacagtatt      120

ttctccaagg tacactccga tcggagtgta tacccatcag caggtgtcct ctttgttcat      180

gttttggaaa gagaatattt taagggggaa tttccacctt acccaaaacc tggcgagatt      240

agtaatgatc ccataacatt taatacaaat ttaatgggtt acccagaccg acctggatgg      300

cttcgatata tccaaaggac accatatagt gatggagtcc tatatgggtc cccaacagct      360

gaaaatgtgg ggaagccaac aatcattgag ataactgcct acaacaggcg cacctttgag      420

actgcaaggc ataatttgat aattaatata atgtctgcag aagacttccc gttgccatat      480

caagcagaat tcttcattaa gaatatgaat gtagaagaaa tgttggccag tgaggttctt      540

ggagactttc ttggcgcagt gaaaaatgtg tggcagccag agcgcctgaa cgccataaac      600

atcacatcgg ccctagacag gggtggcagg gtgccacttc ccattaatga cctgaaggag      660

ggcgtttatg tcatggttgg tgcagatgtc ccgttttctt cttgtttacg agaagttgaa      720

aatccacaga atcaattgag atgtagtcaa gaaatggagc ctgtaataac atgtgataaa      780

aaatttcgta ctcaatttta cattgactgg tgcaaaattt cattggttga taaaacaaag      840

caagtgtcca cctatcagga agtgattcgt ggagagggga ttttacctga tggtggagaa      900

tacaaacccc cttctgattc tttgaaaagc agagactatt acacggattt c               951


<210>  4924
<211>  831
<212>  DNA
<213>  Homo Sapiens

<400>  4924
gccccagtga acggttccaa gtggacttat tttggtcctg atggggagaa tagctggtcc       60

aagaagtacc cgtcgtgtgg gggcctgctg cagtccccca tagacctgca cagtgacatc      120

ctccagtatg acgccagcct cacgcccctc gagttccaag gctacaatct gtctgccaac      180

aagcagtttc tcctgaccaa caatggccat tcagtgaagc tgaacctgcc ctcggacatg      240

cacatccagg gcctccagtc tcgctacagt gccacgcagc tgcacctgca ctgggggaac      300

ccgaatgacc cgcacggctc tgagcacacc gtcagcggac agcacttcgc cgccgagctg      360

cacattgtcc attataactc agacctttat cctgacgcca gcactgccag caacaagtca      420

gaaggcctcg ctgtcctggc tgttctcatt gagatgggct ccttcaatcc gtcctatgac      480

aagatcttca gtcaccttca acatgtaaag tacaaaggcc aggaagcatt cgtcccggga      540

ttcaacattg aagagctgct tccggagagg accgctgaat attaccgcta ccgggggtcc      600

ctgaccacac ccccttgcaa ccccactgtg ctctggacag ttttccgaaa ccccgtgcaa      660

atttcccagg agcagctgct ggctttggag acagccctgt actgcacaca catggacgac      720

ccttccccca gagaaatgat caacaacttc cggcaggtcc agaagttcga tgagaggctg      780

gtatacacct ccttctccca agtgcaagtc tgtactgcgg caggactgag t               831


<210>  4925
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  4925
atgtccggca ccaaattgga ggactccccc ccttgtcgca actggtcatc tgcttcggag       60

ctgaatgaaa ctcaagagcc ctttttaaac cccaccgact atgacgacga ggaattcctg      120

cggtacctgt ggagggaata cctgcacccg aaagaatatg ag                         162


<210>  4926
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  4926
tacatttcgc agaatgacat gatcgccatt cttgattatc ataatcaagt tcggggcaaa       60

gtgttcccac cggcagcaaa tatggaatat atggtttggg atgaaaatct tgcaaaatcg      120

gcagaggctt gggcggctac ttgcatttgg gaccatggac cttcttactt actgagattt      180

ttgggccaaa atctatctgt acgcactgga agatatcgct ctattctcca gttggtcaag      240

ccatggtatg atgaagtgaa agattatgct tttccatatc cccaggattg caaccccaga      300

tgtcctatga gatgttttgg tcccatgtgc acacattata cgcagatggt ttgggccact      360

tccaatcgga taggatgcgc aattcatact tgccaaaaca tgaatgtttg gggatctgtg      420

tggcgacgtg cagtttactt ggtatgcaac tatgccccaa agggcaattg gattggagaa      480

gcaccatata aagtaggggt accatgttca tcttgtcctc caagttatgg gggatcttgt      540

actgacaatc tgtgttttcc aggagttacg tcaaactacc tgtactggtt taaa            594


<210>  4927
<211>  888
<212>  DNA
<213>  Homo Sapiens

<400>  4927
aaacccacag aaaagaagga ccgtgtacat catgagcctc agctcagtga caaggttcac       60

aatgatgctc agagttttga ttatgaccat gatgccttct tgggtgctga agaagcaaag      120

acctttgatc agctgacacc agaagagagc aaggaaaggc ttggaaagat tgtaagtaaa      180

atagatggcg acaaggacgg gtttgtcact gtggatgagc tcaaagactg gattaaattt      240

gcacaaaagc gctggattta cgaggatgta gagcgacagt ggaaggggca tgacctcaat      300

gaggacggcc tcgtttcctg ggaggagtat aaaaatgcca cctacggcta cgttttagat      360

gatccagatc ctgatgatgg atttaactat aaacagatga tggttagaga tgagcggagg      420

tttaaaatgg cagacaagga tggagacctc attgccacca aggaggagtt cacagctttc      480

ctgcaccctg aggagtatga ctacatgaaa gatatagtag tacaggaaac aatggaagat      540

atagataaga atgctgatgg tttcattgat ctagaagagt atattggtga catgtacagc      600

catgatggga atactgatga gccagaatgg gtaaagacag agcgagagca gtttgttgag      660

tttcgggata agaaccgtga tgggaagatg gacaaggaag agaccaaaga ctggatcctt      720

ccctcagact atgatcatgc agaggcagaa gccaggcacc tggtctatga atcagaccaa      780

aacaaggatg gcaagcttac caaggaggag atcgttgaca agtatgactt atttgttggc      840

agccaggcca cagattttgg ggaggcctta gtacggcatg atgagttc                   888


<210>  4928
<211>  984
<212>  DNA
<213>  Homo Sapiens

<400>  4928
tctccatctg gagtgcggct ggtggggggc ctccaccgct gtgaagggcg ggtggaggtg       60

gaacagaaag gccagtgggg caccgtgtgt gatgacggct gggacattaa ggacgtggct      120

gtgttgtgcc gggagctggg ctgtggagct gccagcggaa cccctagtgg tattttgtat      180

gagccaccag cagaaaaaga gcaaaaggtc ctcatccaat cagtcagttg cacaggaaca      240

gaagatacat tggctcagtg tgagcaagaa gaagtttatg attgttcaca tgatgaagat      300

gctggggcat cgtgtgagaa cccagagagc tctttctccc cagtcccaga gggtgtcagg      360

ctggctgacg gccctgggca ttgcaaggga cgcgtggaag tgaagcacca gaaccagtgg      420

tataccgtgt gccagacagg ctggagcctc cgggccgcaa aggtggtgtg ccggcagctg      480

ggatgtggga gggctgtact gactcaaaaa cgctgcaaca agcatgccta tggccgaaaa      540

cccatctggc tgagccagat gtcatgctca ggacgagaag caacccttca ggattgccct      600

tctgggcctt gggggaagaa cacctgcaac catgatgaag acacgtgggt cgaatgtgaa      660

gatccctttg acttgagact agtaggagga gacaacctct gctctgggcg actggaggtg      720

ctgcacaagg gcgtatgggg ctctgtctgt gatgacaact ggggagaaaa ggaggaccag      780

gtggtatgca agcaactggg ctgtgggaag tccctctctc cctccttcag agaccggaaa      840

tgctatggcc ctggggttgg ccgcatctgg ctggataatg ttcgttgctc aggggaggag      900

cagtccctgg agcagtgcca gcacagattt tgggggtttc acgactgcac ccaccaggaa      960

gatgtggctg tcatctgctc agga                                             984


<210>  4929
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  4929
tgtattggag tactggagca gaacaatttt tccctgaata gaagaatgca gaaagcacgt       60

cattgtggcc attgtcctga ggagtggatt acatattcca acagttgtta ttacattggt      120

aaggaaagaa gaacttggga agaaagagtt tgctggcctg tgcttcgaag aactctgatc      180

tgctttcta                                                              189


<210>  4930
<211>  948
<212>  DNA
<213>  Homo Sapiens

<400>  4930
atggccacgt ttgtggagct cagtaccaaa gccaagatgc ccattgtggg cctgggcact       60

tggaagtctc ctcttggcaa agtgaaagaa gcagtgaagg tggccattga tgcaggatat      120

cggcacattg actgtgccta tgtctatcag aatgaacatg aagtggggga agccatccaa      180

gagaagatcc aagagaaggc tgtgaagcgg gaggacctgt tcatcgtcag caagttgtgg      240

cccactttct ttgagagacc ccttgtgagg aaagcctttg agaagaccct caaggacctg      300

aagctgagct atctggacgt ctatcttatt cactggccac agggattcaa gtctggggat      360

gaccttttcc ccaaagatga taaaggtaat gccatcggtg gaaaagcaac gttcttggat      420

gcctgggagg ccatggagga gctggtggat gaggggctgg tgaaagccct tggggtctcc      480

aatttcagcc acttccagat cgagaagctc ttgaacaaac ctggactgaa atataaacca      540

gtgactaacc aggttgagtg tcacccatac ctcacacagg agaaactgat ccagtactgc      600

cactccaagg gcatcaccgt tacggcctac agccccctgg gctctccgga tagaccttgg      660

gccaagccag aagacccttc cctgctggag gatcccaaga ttaaggagat tgctgcaaag      720

cacaaaaaaa ccgcagccca ggttctgatc cgtttccata tccagaggaa tgtgattgtc      780

atccccaagt ctgtgacacc agcacgcatt gttgagaaca ttcaggtctt tgactttaaa      840

ttgagtgatg aggagatggc aaccatactc agcttcaaca gaaactggag ggcctgtaac      900

gtgttgcaat cctctcattt ggaagactat cccttcgatg cagaatat                   948


<210>  4931
<211>  1131
<212>  DNA
<213>  Homo Sapiens

<400>  4931
gcttttgatc aaaaatctta cttttatagg agcagttttc aactcctaaa tgttgaatat       60

aatagtcagt taaattcacc agctacacag gaatacagga ctttgagtgg aagaattgaa      120

tctctgatta ctaaaacatt caaagaatca aatttaagaa atcagttcat cagagctcat      180

gttgccaaac tgaggcaaga tggtagtggt gtgagagcgg atgttgtcat gaaatttcaa      240

ttcactagaa ataacaatgg agcatcaatg aaaagcagaa ttgagtctgt tttacgacaa      300

atgctgaata actctggaaa cctggaaata aacccttcaa ctgagataac atcacttact      360

gaccaggctg cagcaaattg gcttattaat gaatgtgggg ccggtccaga cctaataaca      420

ttgtctgagc agagaatcct tggaggcact gaggctgagg agggaagctg gccgtggcaa      480

gtcagtctgc ggctcaataa tgcccaccac tgtggaggca gcctgatcaa taacatgtgg      540

atcctgacag cagctcactg cttcagaagc aactctaatc ctcgtgactg gattgccacg      600

tctggtattt ccacaacatt tcctaaacta agaatgagag taagaaatat tttaattcat      660

aacaattata aatctgcaac tcatgaaaat gacattgcac ttgtgagact tgagaacagt      720

gtcaccttta ccaaagatat ccatagtgtg tgtctcccag ctgctaccca gaatattcca      780

cctggctcta ctgcttatgt aacaggatgg ggcgctcaag aatatgctgg ccacacagtt      840

ccagagctaa ggcaaggaca ggtcagaata ataagtaatg atgtatgtaa tgcaccacat      900

agttataatg gagccatctt gtctggaatg ctgtgtgctg gagtacctca aggtggagtg      960

gacgcatgtc agggtgactc tggtggccca ctagtacaag aagactcacg gcggctttgg     1020

tttattgtgg ggatagtaag ctggggagat cagtgtggcc tgccggataa gccaggagtg     1080

tatactcgag tgacagccta ccttgactgg attaggcaac aaactgggat c              1131


<210>  4932
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  4932
aaaaagaaag ggtcccaagg tgccatcccc ccgccagaca aggcccagca caatgactca       60

gagcagactc agtcgcccca gcagcctggc tccaggaacc gggggcgggg ccaagggcgg      120

ggcactgcca tgcccgggga ggaggtgctg gagtccagcc aagaggccct gcatgtgacg      180

gagcgcaaat acctgaagcg agactggtgc aaaacccagc cgcttaagca gaccatccac      240

gaggaaggct gcaacagtcg caccatcatc aaccgcttct gttacggcca gtgcaactct      300

ttctacatcc ccaggcacat ccggaaggag gaaggttcct ttcagtcctg ctccttctgc      360

aagcccaaga aattcactac catgatggtc acactcaact gccctgaact acagccacct      420

accaagaaga agagagtcac acgtgtgaag cagtgtcgtt gcatatccat cgatttggat      480


<210>  4933
<211>  2142
<212>  DNA
<213>  Homo Sapiens

<400>  4933
tccgaccggc cccggggccg agacccggtc aacccagaga agctgctggt gatcactgtg       60

gccacagctg aaaccgaggg gtacctgcgt ttcctgcgct ctgcggagtt cttcaactac      120

actgtgcgga ccctgggcct gggagaggag tggcgagggg gtgatgtggc tcgaacagtt      180

ggtggaggac agaaggtccg gtggttaaag aaggaaatgg agaaatacgc tgaccgggag      240

gatatgatca tcatgtttgt ggatagctac gacgtgattc tggccggcag ccccacagag      300

ctgctgaaga agttcgtcca gagtggcagc cgcctgctct tctctgcaga gagcttctgc      360

tggcccgagt gggggctggc ggagcagtac cctgaggtgg gcacggggaa gcgcttcctc      420

aattctggtg gattcatcgg ttttgccacc accatccacc aaatcgtgcg ccagtggaag      480

tacaaggatg atgacgacga ccagctgttc tacacacggc tctacctgga cccaggactg      540

agggagaaac tcagccttaa tctggatcat aagtctcgga tctttcagaa cctcaacggg      600

gctttagatg aagtggtttt aaagtttgat cggaaccgtg tgcgtatccg gaacgtggcc      660

tacgacacgc tccccattgt ggtccatgga aacggtccca ctaagctgca gctcaactac      720

ctgggaaact acgtccccaa tggctggact cctgagggag gctgtggctt ctgcaaccag      780

gaccggagga cactcccggg ggggcagcct cccccccggg tgtttctggc cgtgtttgtg      840

gaacagccta ctccgtttct gccccgcttc ctgcagcggc tgctactcct ggactatccc      900

cccgacaggg tcaccctttt cctgcacaac aacgaggtct tccatgaacc ccacatcgct      960

gactcctggc cgcagctcca ggaccacttc tcagctgtga agctcgtggg gccggaggag     1020

gctctgagcc caggcgaggc cagggacatg gccatggacc tgtgtcggca ggaccccgag     1080

tgtgagttct acttcagcct ggacgccgac gctgtcctca ccaacctgca gaccctgcgt     1140

atcctcattg aggagaacag gaaggtgatc gcccccatgc tgtcccgcca cggcaagctg     1200

tggtccaact tctggggcgc cctgagcccc gatgagtact acgcccgctc cgaggactac     1260

gtggagctgg tgcagcggaa gcgagtgggt gtgtggaatg taccatacat ctcccaggcc     1320

tatgtgatcc ggggtgatac cctgcggatg gagctgcccc agagggatgt gttctcgggc     1380

agtgacacag acccggacat ggccttctgt aagagctttc gagacaaggg catcttcctc     1440

catctgagca atcagcatga atttggccgg ctcctggcca cttccagata cgacacggag     1500

cacctgcacc ccgacctctg gcagatcttc gacaaccccg tcgactggaa ggagcagtac     1560

atccacgaga actacagccg ggccctggaa ggggaaggaa tcgtggagca gccatgcccg     1620

gacgtgtact ggttcccact gctgtcagaa caaatgtgtg atgagctggt ggcagagatg     1680

gagcactacg gccagtggtc aggcggccgg catgaggatt caaggctggc tggaggctac     1740

gagaatgtgc ccaccgtgga catccacatg aagcaggtgg ggtacgagga ccagtggctg     1800

cagctgctgc ggacgtatgt gggccccatg accgagagcc tgtttcccgg ttaccacacc     1860

aaggcgcggg cggtgatgaa ctttgtggtt cgctaccggc cagacgagca gccgtctctg     1920

cggccacacc acgactcatc caccttcacc ctcaacgttg ccctcaacca caagggcctg     1980

gactatgagg gaggtggctg ccgcttcctg cgctacgact gtgtgatctc ctccccgagg     2040

aagggctggg cactcctgca ccccggccgc ctcacccact accacgaggg gctgccaacg     2100

acctggggca cacgctacat catggtgtcc tttgtcgacc cc                        2142


<210>  4934
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  4934
ggaaagctcc ctttctcaag aatgcccatc tgtgaacaca tggtagagtc tccaacctgt       60

tcccagatgt ccaacctggt ctgcggcact gatgggctca catatacgaa tgaatgccag      120

ctctgcttgg cccggataaa aaccaaacag gacatccaga tcatgaaaga tggcaaatgc      180


<210>  4935
<211>  1386
<212>  DNA
<213>  Homo Sapiens

<400>  4935
gggaagctac tggtagtgcc catggatggg agccactggt tcaccatgag gtcggtggtg       60

gagaaactca ttctcagggg gcatgaggtg gttgtagtca tgccagaggt gagttggcaa      120

ctgggaagat cactgaattg cacagtgaag acttattcaa cttcatatac cctggaggat      180

ctggaccggg agttcaaggc ttttgcccat gctcaatgga aagcacaagt acgaagtata      240

tattctctat taatgggttc atacaatgac atttttgact tatttttttc aaattgcagg      300

agtttgttta aagacaaaaa attagtagaa tacttaaagg agagttcttt tgatgcagtg      360

tttctcgatc cttttgataa ctgtggctta attgttgcca aatatttctc cctcccctcc      420

gtggtcttcg ccaggggaat actttgccac tatcttgaag aaggtgcaca gtgccctgct      480

cctctttcct atgtccccag aattctctta gggttctcag atgccatgac tttcaaggag      540

agagtacgga accacatcat gcacttggag gaacatttat tatgccaccg ttttttcaaa      600

aatgccctag aaatagcctc tgaaattctc caaacacctg ttacggagta tgatctctac      660

agccacacat caatttggtt gttgcgaacg gactttgttt tggactatcc caaacccgtg      720

atgcccaaca tgatcttcat tggtggtatc aactgccatc agggaaagcc gttgcctatg      780

gaatttgaag cctacattaa tgcttctgga gaacatggaa ttgtggtttt ctctttggga      840

tcaatggtct cagaaattcc agagaagaaa gctatggcaa ttgctgatgc tttgggcaaa      900

atccctcaga cagtcctgtg gcggtacact ggaacccgac catcgaatct tgcgaacaac      960

acgatacttg ttaagtggct accccaaaac gatctgcttg gtcacccgat gacccgtgcc     1020

tttatcaccc atgctggttc ccatggtgtt tatgaaagca tatgcaatgg cgttcccatg     1080

gtgatgatgc ccttgtttgg tgatcagatg gacaatgcaa agcgcatgga gactaaggga     1140

gctggagtga ccctgaatgt tctggaaatg acttctgaag atttagaaaa tgctctaaaa     1200

gcagtcatca atgacaaaag ttacaaggag aacatcatgc gcctctccag ccttcacaag     1260

gaccgcccgg tggagccgct ggacctggcc gtgttctggg tggagtttgt gatgaggcac     1320

aagggcgcgc cacacctgcg ccccgcagcc cacgacctca cctggtacca gtaccattcc     1380

ttggac                                                                1386


<210>  4936
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  4936
aaagacccaa aaaagaatga gacgggggtg ctgaggaaat taaaacccgt caatgcctca       60

aatgccaacg tgaagcagtg tctgtggttt gccatgcaag aatacaacaa agagagcgag      120

gacaagtatg tcttcctggt ggtcaagaca ctgcaagccc agcttcaggt cacaaatctt      180

ctggaatacc ttattgatgt agaaattgcc cgcagcgatt gcagaaagcc tttaagcact      240

aatgaaatct gcgccattca agaaaactcc aagctgaaaa ggaaattaag ctgcagcttt      300

ttggtaggag cacttccctg gaatggtgaa ttcactgtga tggagaaaaa gtgtgaagat      360

gct                                                                    363


<210>  4937
<211>  453
<212>  DNA
<213>  Homo Sapiens

<400>  4937
aatgccattc aggccaggtc ttcctcctat agtggagagt atggaagtgg tggtggaaag       60

cgattctctc attctggcaa ccagttggac ggccccatca ccgccctccg ggtccgagtc      120

aacacatact acatcgtagg tcttcaggtg cgctatggca aggtgtggag cgactatgtg      180

ggtggtcgca acggagacct ggaggagatc tttctgcacc ctggggaatc agtgatccag      240

gtttctggga agtacaagtg gtacctgaag aagctggtat ttgtgacaga caagggccgc      300

tatctgtctt ttgggaaaga cagtggcaca agtttcaatg ccgtcccctt gcaccccaac      360

accgtgctcc gcttcatcag tggccggtct ggttctctca tcgatgccat tggcctgcac      420

tgggatgttt accccactag ctgcagcaga tgc                                   453


<210>  4938
<211>  1128
<212>  DNA
<213>  Homo Sapiens

<400>  4938
tatcgcctct tccctggtga acccaaatgg aaaaaaaata ctttgacata cagaatatct       60

aaatacacac cttccatgag ttctgtcgag gtggacaaag cagtggagat ggccttgcag      120

gcctggagta gcgccgtccc tctgagcttt gtcagaataa actcaggaga agcggatatt      180

atgatatctt ttgaaaatgg agatcacggg gattcctatc cattcgatgg gcctcggggg      240

actctagccc atgcatttgc tcctggagaa ggcctgggag gagatacaca tttcgacaat      300

gctgagaagt ggactatggg aacgaatggt tttaatttgt ttaccgttgc tgctcatgaa      360

tttggccatg ccctgggcct ggcccattcc acagacccat cagcactgat gtacccaact      420

tataagtaca agaatcccta tggattccac ctccccaaag atgatgtgaa agggatccag      480

gcattatacg gacctcggaa agtattcctg gggaagccca ctctgcccca tgccccccat      540

cacaagccat ccatccctga cctctgtgac tccagctcat cctttgacgc tgtgacaatg      600

ctggggaagg agctcctgct cttcaaggac cggattttct ggagacggca ggttcacttg      660

cggacaggaa ttcggcccag cactattacc agctccttcc cccagctcat gtccaatgtg      720

gatgcagctt acgaagtggc tgagaggggc actgcttact tcttcaaagg tccccactac      780

tggataacaa gaggattcca aatgcaaggt cctcctcgga ctatttatga ctttggattt      840

ccaaggcacg tgcagcaaat agatgctgct gtctacctca gggagccaca gaagaccctt      900

ttctttgtgg gagatgaata ctacagctac gacgaaagga aaaggaaaat ggaaaaagac      960

tatccaaaga atactgaaga agaattttca ggagtaaatg gccaaatcga tgctgctgta     1020

gaattaaatg gctacattta cttcttttca ggaccaaaaa catacaagta tgacacagag     1080

aaggaagatg tggttagtgt ggtgaaatct agttcctgga ttggttgc                  1128


<210>  4939
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  4939
tgccaggagg ctaactacgg tgccctcctc cgggagctct gcctcaccca gttccaggta       60

gacatggagg ccgtcgggga gacgctgtgg tgtgactggg gcaggaccat caggagctac      120

agggagctgg ccgactgcac ctggcacatg gcggagaagc tgggctgctt ctggcccaat      180

gcagaggtgg acaggttctt cctggcagtg catggccgct acttcaggag ctgccccatc      240

tcaggcaggg ccgtgcggga cccgcccggc agc                                   273


<210>  4940
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  4940
cagcctcttc ccaccacagg cacaccaggg tcagaagggg ggacggtgaa gaactatgag       60

acagctgtcc aattttgctg gaatcattat aaggatcaaa tggatcctat cgaaaaggat      120

tggtgcgact gggccatgat tagcaggcct tatagcaccc tgcgagattg cctggagcac      180

tttgcagagt tgtttgacct gggcttcccc aatcccttgg cagagaggat catctttgag      240

actcaccaga tccactttgc caactgctcc ctggtgcagc ccaccttctc tgacccccca      300

gaggatgta                                                              309


<210>  4941
<211>  285
<212>  DNA
<213>  Homo Sapiens

<400>  4941
agagcaggcg gctgcaacga gacaggcatg ttggagaggc tgcccctgtg tgggaaggct       60

ttcgcagaca tgatgggcaa ggtggacgtc tggaagtggt gcaacctgtc cgagttcatc      120

gtgtactatg agagtttcac caactgcacc gagatggagg ccaatgtcgt gggctgctac      180

tggcccaacc ccctggccca gggcttcatc accggcatcc acaggcagtt cttctccaac      240

tgcaccgtgg acagggtcca cttggaggac cccccagacg aggtt                      285


<210>  4942
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  4942
cttcccaaat ctgtggattg gagaaagaaa ggctacgtga cgccagtgaa gaatcagaaa       60

cagtgtggtt cttgttgggc ttttagtgcg actggtgctc ttgaaggaca gatgttccgg      120

aaaactggga aacttgtctc actgagcgag cagaatctgg tggactgttc gcgtcctcaa      180

ggcaatcagg gctgcaatgg tggcttcatg gctagggcct tccagtatgt caaggagaac      240

ggaggcctgg actctgagga atcctatcca tatgtagcag tggatgaaat ctgtaagtac      300

agacctgaga attctgttgc taatgacact ggcttcacag tggtcgcacc tggaaaggag      360

aaggccctga tgaaagcagt cgcaactgtg gggcccatct ccgttgctat ggatgcaggc      420

cattcgtcct tccagttcta caaatcaggc atttattttg aaccagactg cagcagcaaa      480

aacctggatc atggtgttct ggtggttggc tacggctttg aaggagcaaa ttcgaataac      540

agcaagtatt ggctcgtcaa aaacagctgg ggtccagaat ggggctcgaa tggctatgta      600

aaaatagcca aagacaagaa caaccactgt ggaatcgcca cagcagccag ctaccccaat      660

gtg                                                                    663


<210>  4943
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  4943
cagccgtacc acggagagaa gggcatctcc gtgccggacc acggcttctg ccagcccatc       60

tccatcccgc tgtgcacgga catcgcctac aaccagacca tcctgcccaa cctgctgggc      120

cacacgaacc aagaggacgc gggcctcgag gtgcaccagt tctacccgct ggtgaaggtg      180

cagtgttctc ccgaactccg ctttttctta tgctccatgt atgcgcccgt gtgcaccgtg      240

ctcgatcagg ccatcccgcc gtgtcgttct ctgtgcgagc gcgcccgcca gggctgcgag      300

gcgctcatga acaagttcgg cttccagtgg cccgagcggc tgcgctgcga gaacttcccg      360

gtgcacggtg cgggcgagat ctgcgtgggc cagaacacgt cggacggctc cgggggccca      420

ggcggcggcc ccactgccta ccctaccgcg ccctacctgc cggacctgcc cttcaccgcg      480

ctgcccccgg gggcctcaga tggcaggggg cgtcccgcct tccccttctc atgcccccgt      540

cagctcaagg tgcccccgta cctgggctac cgcttcctgg gtgagcgcga ttgtggcgcc      600

ccgtgcgaac cgggccgtgc caacggcctg atgtacttta aggaggagga gaggcgcttc      660

gcccgcctct gg                                                          672


<210>  4944
<211>  2172
<212>  DNA
<213>  Homo Sapiens

<400>  4944
cagcctcccc actgcccctc tgtatcccat agggcccagc cctggccaca ccctggccag       60

agccagctgt ttgcagacct gagccgagag gagttgacag ctgtgatgcg ctttctgacc      120

cagcggctgg ggccagggct ggtggacgca gcccaggctc agccctcgga caactgcatc      180

ttctcagtgg agctgcagct gccccccaag gctgcagccc tggcccacct ggacaggggg      240

agccccccac ctgcccggga ggcactggcc atcgtcctct ttggtggaca accccaaccc      300

aatgtgagtg agctggtggt ggggccgctg cctcacccct cgtacatgcg ggatgtgact      360

gtggagcgtc acggcgggcc cctgccctat caccgtcgcc cggtgctgag agctgagttt      420

acacagatgt ggaggcatct gaaagaggtg gagctaccca aggcacccat cttcctgtcg      480

tccaccttca actacaatgg ctctaccctg gcagctgtgc atgccacccc tcggggcttg      540

cgctcagggg accgagctac ctggatggcc ctctaccata acatctcagg ggttggtctt      600

ttccttcacc ccgtggggct ggagctacta ctggaccaca gggcactgga ccctgcccac      660

tggactgtcc agcaggtctt ctaccttggg cactactatg cagacttggg ccagttggaa      720

cgggagttta agtctggccg gttggaagtg gttagagtcc ctctacctcc accaaatgga      780

gcttcatccc tgaggtctcg gaactctcca ggtcctcttc cccctcttca gttctcgccc      840

cagggttccc agtacagtgt gcaaggaaac ctggtggtat cctccctctg gtcatttacc      900

tttggccatg gggtgttcag cggcctgagg atttttgatg ttcggttcca gggtgagcga      960

atagcctatg aagtcagtgt ccaggagtgt gtatctatct atggtgccga ttcacccaag     1020

acgatgctga ctcgctattt ggatagcagc tttggactcg gccgtaacag ccgaggcttg     1080

gtgcggggag tggactgccc ctatcaagcc acgatggtgg acatccatat attagtgggc     1140

aaaggggcag tccagctgct tccaggggct gtgtgtgtat ttgaggaagc ccagggactg     1200

ccccttcgaa ggcaccacaa ttaccttcaa aatcatttct atggtggttt ggccagctca     1260

gcccttgtgg tcaggtctgt gtcatctgtg ggcaactatg actacatttg ggactttgtg     1320

ttgtacccaa atggggcact tgaagggcgg gtccatgcca cgggttatat caacacagct     1380

ttcctgaaag ggggagagga gggcctcctc tttgggaacc gtgtggggga aagagtgctg     1440

ggaacggtgc acacacatgc cttccacttc aagctggacc tggatgtggc agggctgaaa     1500

aactgggtgg tagctgaaga cgtggtgttt aaacctgtgg ctgccccctg gaacccggag     1560

cactggctac agcgcccaca gctgactcgg caggtcctgg gaaaggagga cctgacagct     1620

ttttccttgg gaagccccct accccgctac ctctacctgg ctagcaacca gactaatgcg     1680

tggggtcacc agcgcgggta ccgaatccag atccacagcc cccttggcat acacataccc     1740

ctggagagtg acatggagag ggccctcagc tgggggagat accagcttgt ggtgacccag     1800

agaaaggagg aggagtcaca gagcagtagc atctatcacc agaatgacat ctggacaccc     1860

acagttacct ttgctgactt catcaacaat gaaaccctct taggagagga tctggtggct     1920

tgggtcacag ccagcttcct gcacattccc catgccgagg acatcccaaa cacagtgact     1980

ctggggaaca gagttggctt cttgctccga ccctataact tctttgatga ggacccctcc     2040

atcttctccc ctggcagtgt ctactttgag aagggccagg atgctgggct ctgcagcatc     2100

aatcctgtgg cctgcctccc cgacctggca gcctgtgtcc cggacttacc ccctttctct     2160

taccacggct tc                                                         2172


<210>  4945
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  4945
cggatggcca agaagcgggt catcgtgaag aagttaccca tcgtggagac tttaggttgc       60

tgcagcgttc tctgttctga caagacgggg actctgactg ccaatgaaat gacagtgacc      120

cagcttgtaa cgtcagatgg gcttcgtgcc gaggtcagcg gagttgggta tgacggtcaa      180

gggactgtgt gtcttctacc atccaaggaa gtcattaagg aattttccaa tgtctcagtg      240

ggaaagttag tggaggcggg ctgtgttgcc aacaatgcgg tcatcagaaa gaacgccgtg      300

atggggcagc ccaccgaggg tgcattgatg gccctggcga tgaagatgga cttaagtgat      360

attaaaaatt catatataag aaaaaaagag attccattca gttcagagca gaagtggatg      420

gcggtgaaat gcagtctgaa gactgaggat caggaagaca tttacttcat gaaaggggcc      480

ttggaagagg tgatccgcta ctgcaccatg tacaacaacg ggggcatccc cctgccgctg      540

acgccccagc agaggtcatt ctgcctgcag gaagagaaga ggatggggtc gctcggtttg      600

cgggtgctgg ccctggcttc tgggcccgag ctggggcggc tgacgtttct cggtcttgtg      660

ggcatcattg accccccgag agttggcgtg aaggaagcag tccaggttct ctccgagtct      720

ggtgtgtctg tgaagatgat aacgggggat gccctggaga cggccttggc cataggaaga      780

aacatcggcc tgtgcaacgg gaagctgcaa gccatgtccg gggaggaggt ggacagcgtg      840

gagaagggcg agctggccga ccgcgtgggg aaggtgtccg tgttcttcag gaccagccca      900

aagcacaagc tcaaaatcat caaggctctg caggagtcag gggcgatcgt ggccatgact      960

ggggatgggg tgaacgacgc agtggccctg aagtctgcag acattgggat cgccatgggg     1020

cagacaggga cggacgtcag caaagaggcc gccaacatga tcctggtgga tgatgacttc     1080

tcagccatca tgaatgcagt ggaggaaggc aagggtattt tttacaacat caaaaacttt     1140

gtccgattcc agctgagcac gagcatctcc gccctgagtc tcatcactct gtcc           1194


<210>  4946
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  4946
agttgtggaa aagtgctggt gtgggccgca gaatacagcc attggatgaa tatgaagaca       60

atcctgaaag agcttgttca gagaggtcat gaggtgactg tactggcatc ttcagcttcc      120

attctttttg atcccaatga tgcatccact cttaaatttg aagtttatcc tacatcttta      180

actaaaactg aatttgagaa tatcatcatg caacaggtta agagatggtc agacattcga      240

aaagatagct tttggttata tttttcacaa gaacaagaaa tcctgtggga attatatgac      300

atatttagaa acttctgtaa agatgtagtt tcaaataaga aagttatgaa aaaactacaa      360

gagtcaagat ttgacatcgt ttttgcagat gctgtttttc cctgtggtga gctgctggct      420

gcgctactta acatacggtt tgtgtacagt ctccgcttta ctcctggcta cacaattgaa      480

aggcacagtg gaggactgat tttccctcct tcctacatac ctattgttat gtcaaaatta      540

agtgatcaaa tgactttcat ggagagggta aaaaatatga tctatgtgct ttattttgac      600

ttttggttcc aaatgtctga tatgaagaag tgggatcagt tttacagtga agttttagga      660

agacccacta ccttatttga gacaatggga aaagctgaca tatggcttat gcgaaactcc      720

tggagttttc aatttcctca tccattctta ccaaacgttg attttgttgg aggattccac      780

tgcaaacctg ccaaacccct acctaaggaa atggaggagt ttgtacagag ctctggagaa      840

aatggtgttg tggtgttttc tctggggtca gtgataagta acatgacagc agaaagggcc      900

aatgtaattg caacagccct tgccaagatc ccacaaaagg ttctgtggag atttgacggg      960

aataaaccag atgccttagg tctcaatact cggctgtaca agtggatacc ccagaatgac     1020

cttctaggtc atccaaaaac cagagctttt ataactcatg gtggagccaa tggcatctat     1080

gaggcaatct accatgggat ccctatggtg ggcattccat tgttttttga tcaacctgat     1140

aacattgctc acatgaaggc caagggagca gctgttagat tggacttcaa cacaatgtcg     1200

agtacagacc tgctgaatgc actgaagaca gtaattaatg atcctttata taaagagaat     1260

attatgaaat tatcaagaat tcaacatgat caaccagtaa agcccctgga tcgagcagtc     1320

ttctggattg aatttgtcat gccccacaaa ggagccaaac accttcgagt tgcagcccat     1380

gacctcacct ggttccagta ccactctttg gat                                  1413


<210>  4947
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  4947
gcaagatctc gaagtgctcc aatgtcacct tctgattttc tggataaatt aatgggcagg       60

acatcaggat atgatgcaag aatcagaccc aattttaaag gccctccagt taatgtcaca      120

tgcaacatat tcatcaacag ctttggctct atcgcagaga cgaccatgga ttacagagtg      180

aatatctttc ttcgtcagaa atggaatgat ccccgcctcg cgtacagtga atatcctgac      240

gactctttag acctcgaccc ctccatgttg gactccattt ggaaacctga tttgttcttt      300

gccaatgaaa agggtgccaa ctttcatgaa gtcactacag acaacaaatt gctaagaatt      360

ttcaaaaatg gaaatgttct ttattcaata agattaacat taacactttc ctgtccaatg      420

gatctcaaga attttcccat ggatgtacaa acatgtataa tgcaactgga aagctttggg      480

tacacaatga atgatctcat ttttgaatgg caagatgagg cacccgtaca agtggcagaa      540

ggactcactt tgccccagtt tctgttgaaa gaagaaaaag atttacgata ctgcactaaa      600

cattacaata caggaaagtt tacgtgtata gaagtgcgat tccatctgga gcgacaaatg      660

ggatac                                                                 666


<210>  4948
<211>  1212
<212>  DNA
<213>  Homo Sapiens

<400>  4948
aaccagcaga cttggtttga gggtatcttc ctgtcttcca tgtgccccat caatgtcagc       60

gccagcacct tgtatggaat tatgtttgat gcagggagca ctggaactcg aattcatgtt      120

tacacctttg tgcagaaaat gccaggacag cttccaattc tagaagggga agtttttgat      180

tctgtgaagc caggactttc tgcttttgta gatcaaccta agcagggtgc tgagaccgtt      240

caagggctct tagaggtggc caaagactca atcccccgaa gtcactggaa aaagacccca      300

gtggtcctaa aggcaacagc aggactacgc ttactgccag aacacaaagc caaggctctg      360

ctctttgagg taaaggagat cttcaggaag tcacctttcc tggtaccaaa gggcagtgtt      420

agcatcatgg atggatccga cgaaggcata ttagcttggg ttactgtgaa ttttctgaca      480

ggtcagctgc atggccacag acaggagact gtggggacct tggacctagg gggagcctcc      540

acccaaatca cgttcctgcc ccagtttgag aaaactctgg aacaaactcc taggggctac      600

ctcacttcct ttgagatgtt taacagcact tataagctct atacacatag ttacctggga      660

tttggattga aagctgcaag actagcaacc ctgggagccc tggagacaga agggactgat      720

gggcacactt tccggagtgc ctgtttaccg agatggttgg aagcagagtg gatctttggg      780

ggtgtgaaat accagtatgg tggcaaccaa gaaggggagg tgggctttga gccctgctat      840

gccgaagtgc tgagggtggt acgaggaaaa cttcaccagc cagaggaggt ccagagaggt      900

tccttctatg ctttctctta ctattatgac cgagctgttg acacagacat gattgattat      960

gaaaaggggg gtattttaaa agttgaagat tttgaaagaa aagccaggga agtgtgtgat     1020

aacttggaaa acttcacctc aggcagtcct ttcctgtgca tggatctcag ctacatcaca     1080

gccctgttaa aggatggctt tggctttgca gacagcacag tcttacagct cacaaagaaa     1140

gtgaacaaca tagagacggg ctgggccttg ggggccacct ttcacctgtt gcagtctctg     1200

ggcatctccc at                                                         1212


<210>  4949
<211>  1695
<212>  DNA
<213>  Homo Sapiens

<400>  4949
atggaggact cggactcggc ggcaaagcag ctgggcctgg ctgaggcggc ggcggtggcg       60

gccgcggccg ctgtggcggc ggcggccgcg gccgcggcag gaggcgaggc ggaggagccg      120

gtgctgagca gggacgagga ctcggaggag gacgcagact cggaggcgga gcgggagacg      180

ccgcgggtca cggcagtggc ggtgatggcg gcggagcccg ggcacatgga catgggcgcc      240

gaggccctgc ccggccccga cgaggccgcc gctgccgcag ccttcgcaga ggtgaccaca      300

gtgacagtgg ccaacgtggg ggctgctgca gacaatgtct tcaccacgtc tgtggcgaac      360

gcggcatcca tctcaggaca tgttctgtct ggtaggacgg cccttcagat cggggacagc      420

ctgaacaccg aaaaagcgac actgattgtc gtccacacag atgggagcat cgtggagacc      480

accgggctga aaggcccggc agctcccctc accccaggtc ctcagtctcc tccaacccct      540

ctggctcccg gccaagaaaa aggtggaact aaatacaact gggacccttc tgtgtacgac      600

agtgagctgc ccgtacggtg ccggaacatc agcggcactc tgtacaagaa caggctcggc      660

tcaggcggcc ggggacggtg catcaagcag ggggagaact ggtacagtcc caccgagttt      720

gaggccatgg caggaagagc cagcagtaag gactggaaaa gaagcattcg ctacgcgggc      780

cgacccttgc agtgcctcat ccaggatggg atcttaaacc ctcacgctgc ctcttgcacc      840

tgtgctgcct gctgcgacga catgacctta agtggcccag tcaggctttt tgtgccttac      900

aaaaggcgca agaaggagaa tgaactgccc acaactcccg tgaagaagga ctcccccaag      960

aacatcacat tgcttccagc caccgcggct accaccttca ccgtgacccc ctcgggacag     1020

atcacgacct cgggggcact gacctttgac cgagcgtcca cggtagaggc cactgctgtc     1080

atatcagaga gtccggccca gggcgacgtc ttcgcagggg ccacagtcca agaggccagc     1140

gtgcagcccc catgcagggc cagccaccct gagcctcact accccggcta tcaggacagc     1200

tgccagatcg caccgtttcc agaagctgcg ttgccaacgt cacatcccaa aatagtgttg     1260

acatccctgc ctgcgctggc ggtcccaccc ccgactccca ccaaagcggc acctcccgcg     1320

ttggtcaatg ggctggagct gtcagagccg cggagctggc tgtacctaga agagatggtc     1380

aactccttgc tcaacacagc gcagcagctg aagacgctgt ttgagcaagc caagcatgcc     1440

agcacctacc gagaagctgc cacaaaccag gccaagatcc acgctgacgc agagcggaag     1500

gagcagtcct gcgttaactg cggccgggag gctatgagcg agtgcaccgg ctgccacaag     1560

gtcaactact gctccacctt ctgccaacgc aaggactgga aggatcacca gcacatatgc     1620

ggccagtcag cagctgtcac cgtccaggca gacgaagtcc acgtggctga aagcgtgatg     1680

gagaaggtga ccgtg                                                      1695


<210>  4950
<211>  1533
<212>  DNA
<213>  Homo Sapiens

<400>  4950
gcgctgctgg ctgccgagct caagtcgaaa agttgctcgg aagtgcgacg tctttacgtg       60

tccaaaggct tcaacaagaa cgatgccccc ctccacgaga tcaacggtga tcatttgaag      120

atctgtcccc agggttctac ctgctgctct caagagatgg aggagaagta cagcctgcaa      180

agtaaagatg atttcaaaag tgtggtcagc gaacagtgca atcatttgca agctgtcttt      240

gcttcacgtt acaagaagtt tgatgaattc ttcaaagaac tacttgaaaa tgcagagaaa      300

tccctgaatg atatgtttgt gaagacatat ggccatttat acatgcaaaa ttctgagcta      360

tttaaagatc tcttcgtaga gttgaaacgt tactacgtgg tgggaaatgt gaacctggaa      420

gaaatgctaa atgacttctg ggctcgcctc ctggagcgga tgttccgcct ggtgaactcc      480

cagtaccact ttacagatga gtatctggaa tgtgtgagca agtatacgga gcagctgaag      540

cccttcggag atgtccctcg caaattgaag ctccaggtta ctcgtgcttt tgtagcagcc      600

cgtactttcg ctcaaggctt agcggttgcg ggagatgtcg tgagcaaggt ctccgtggta      660

aaccccacag cccagtgtac ccatgccctg ttgaagatga tctactgctc ccactgccgg      720

ggtctcgtga ctgtgaagcc atgttacaac tactgctcaa acatcatgag aggctgtttg      780

gccaaccaag gggatctcga ttttgaatgg aacaatttca tagatgctat gctgatggtg      840

gcagagaggc tagagggtcc tttcaacatt gaatcggtca tggatcccat cgatgtgaag      900

atttctgatg ctattatgaa catgcaggat aatagtgttc aagtgtctca gaaggttttc      960

cagggatgtg gaccccccaa gcccctccca gctggacgaa tttctcgttc catctctgaa     1020

agtgccttca gtgctcgctt cagaccacat caccccgagg aacgcccaac cacagcagct     1080

ggcactagtt tggaccgact ggttactgat gtcaaggaga aactgaaaca ggccaagaaa     1140

ttctggtcct cccttccgag caacgtttgc aacgatgaga ggatggctgc aggaaacggc     1200

aatgaggatg actgttggaa tgggaaaggc aaaagcaggt acctgtttgc agtgacagga     1260

aatggattag ccaaccaggg caacaaccca gaggtccagg ttgacaccag caaaccagac     1320

atactgatcc ttcgtcaaat catggctctt cgagtgatga ccagcaagat gaagaatgca     1380

tacaatggga acgacgtgga cttctttgat atcagtgatg aaagtagtgg agaaggaagt     1440

ggaagtggct gtgagtatca gcagtgccct tcagagtttg actacaatgc cactgaccat     1500

gctgggaaga gtgccaatga gaaagccgac agt                                  1533


<210>  4951
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  4951
cacatcggac cagcacctga ccccgaggac tggtggagct acaaggataa tctccaggga       60

aacttcgtgc cagggcctcc tttctggggc ctggtgaatg cagcgtggag tctgtgtgct      120

gtggggaagc ggcagagccc cgtggatgtg gagctgaaga gggttcttta tgaccccttt      180

ctgcccccat taaggctcag cactggagga gagaagctcc ggggaacctt gtacaacacc      240

ggccgacatg tctccttcct gcctgcaccc cgacctgtgg tcaatgtgtc tggaggtccc      300

ctcctttaca gccaccgact cagtgaactg cggctgctgt ttggagctcg cgacggagcc      360

ggctcggaac atcagatcaa ccaccagggc ttctctgctg aggtgcagct cattcacttc      420

aaccaggaac tctacgggaa tttcagcgct gcctcccgcg gccccaatgg cctggccatt      480

ctcagcctct ttgtcaacgt tgccagtacc tctaacccat tcctcagtcg cctccttaac      540

cgcgacacca tcactcgcat ctcctacaag aatgatgcct actttcttca agacctgagc      600

ctggagctcc tgttccctga atccttcggc ttcatcacct atcagggctc tctcagcacc      660

ccgccctgct ccgagactgt cacctggatc ctcattgacc gggccctcaa tatcacctcc      720

cttcagatgc actccctgag actcctgagc cagaatcctc catctcagat cttccagagc      780

ctcagcggta acagccggcc cctgcagccc ttggcccaca gggcactgag gggcaacagg      840

gacccccggc accccgagag gcgctgccga ggccccaact accgcctgca tgtggatggt      900

gtcccccatg gtcgc                                                       915


<210>  4952
<211>  951
<212>  DNA
<213>  Homo Sapiens

<400>  4952
tcccgggtct cgggcatccc ctcccggcgc cactggccgg tgccctacaa gcgctttgac       60

ttccgtccaa aacctgatcc ttattgtcaa gctaagtata ctttctgtcc aactggctca      120

cctatcccag ttatggaggg tgatgatgac attgaagttt ttcgattaca agccccagta      180

tgggaattta aatatggaga cctcctggga cacttgaaaa ttatgcatga tgccattgga      240

ttcagaagta cattaactgg caagaactac acaatggaat ggtatgaact tttccaactt      300

ggcaactgta catttcccca tctccgacct gaaatggatg cccctttctg gtgtaatcaa      360

ggcgctgcct gcttttttga gggaattgat gatgttcact ggaaggaaaa tgggacatta      420

gttcaagtag caactatatc aggaaacatg ttcaaccaaa tggcaaagtg ggtgaaacag      480

gacaatgaaa caggaattta ttatgagaca tggaatgtaa aagccagccc agaaaagggg      540

gcagagacat ggtttgattc ctacgactgt tccaaatttg tgttaaggac ctttaacaag      600

ttggctgaat ttggagcaga gttcaagaac atagaaacca actatacaag aatatttctt      660

tacagtggag aacctactta tctgggaaat gaaacatctg tttttgggcc aacaggaaac      720

aagactcttg gtttagccat aaaaagattt tattacccct tcaaaccaca tttgccaact      780

aaagaatttc tgttgagtct cttgcaaatt tttgatgcag tgattgtgca caaacagttc      840

tatttgtttt ataattttga atattggttt ttacctatga aattcccttt tattaaaata      900

acatatgaag aaatcccttt acctatcaga aacaaaacac tctctggttt a               951


<210>  4953
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  4953
gtgaccacct ccaccaatga ctgggtggtg acctgcggct acaccatccc cacctgccgc       60

aagctggatg agctgggctc caaggggctg tgggccgact gcgtcatggc cacggggctg      120

taccactgca agcccctggt ggacatcctc atcctgccgg gctacgtgca ggcctgccgc      180


<210>  4954
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  4954
gattctggct gcaaactcct ggaggacatg gttgaaaaga ccatcaattc cgacatatct       60

atacctgaat acaaagagct tcttcaagag ttcatagaca gtgatgccgc tgcagaggct      120

atggggaaat tcaagcagtg tttcctcaac cagtcacata gaactctgaa aaactttgga      180

ctgatgatgc atacagtgta cgacagcatt tggtgtaata tgaagagtaa t               231


<210>  4955
<211>  870
<212>  DNA
<213>  Homo Sapiens

<400>  4955
aggttcagcc agagcttccg agaggtggcc ggcaggttcc tggcgttgga ggccagcaca       60

cacctgctgg tgttcggcat ggagcagcgg ctgccgccca acagcgagct ggtgcaggcc      120

gtgctgcggc tcttccagga gccggtcccc aaggccgcgc tgcacaggca cgggcggctg      180

tccccgcgca gcgcccgggc ccgggtgacc gtcgagtggc tgcgcgtccg cgacgacggc      240

tccaaccgca cctccctcat cgactccagg ctggtgtccg tccacgagag cggctggaag      300

gccttcgacg tgaccgaggc cgtgaacttc tggcagcagc tgagccggcc ccggcagccg      360

ctgctgctac aggtgtcggt gcagagggag catctgggcc cgctggcgtc cggcgcccac      420

aagctggtcc gctttgcctc gcagggggcg ccagccgggc ttggggagcc ccagctggag      480

ctgcacaccc tggaccttgg ggactatgga gctcagggcg actgtgaccc tgaagcacca      540

atgaccgagg gcacccgctg ctgccgccag gagatgtaca ttgacctgca ggggatgaag      600

tgggccgaga actgggtgct ggagcccccg ggcttcctgg cttatgagtg tgtgggcacc      660

tgccggcagc ccccggaggc cctggccttc aagtggccgt ttctggggcc tcgacagtgc      720

atcgcctcgg agactgactc gctgcccatg atcgtcagca tcaaggaggg aggcaggacc      780

aggccccagg tggtcagcct gcccaacatg agggtgcaga agtgcagctg tgcctcggat      840

ggtgcgctcg tgccaaggag gctccagcca                                       870


<210>  4956
<211>  567
<212>  DNA
<213>  Homo Sapiens

<400>  4956
cgcggcggcc gggaccacgg ggactgggac gaggcctccc ggctgccgcc gctaccaccc       60

cgcgaggacg cggcgcgcgt ggcccgcttc gtgacgcacg tctccgactg gggcgctctg      120

gccaccatct ccacgctgga ggcggtgcgc ggccggccct tcgccgacgt cctctcgctc      180

agcgacgggc ccccgggcgc gggcagcggc gtgccctatt tctacctgag cccgctgcag      240

ctctccgtga gcaacctgca ggagaatcca tatgctacac tgaccatgac tttggcacag      300

accaacttct gcaagaaaca tggatttgat ccacaaagtc ccctttgtgt tcacataatg      360

ctgtcaggaa ctgtgaccaa ggtgaatgaa acagaaatgg atattgcaaa gcattcgtta      420

ttcattcgac accctgagat gaaaacctgg ccttccagcc ataattggtt ctttgctaag      480

ttgaatataa ccaatatctg ggtcctggac tactttggtg gaccaaaaat cgtgacacca      540

gaagaatatt ataatgtcac agttcag                                          567


<210>  4957
<211>  795
<212>  DNA
<213>  Homo Sapiens

<400>  4957
caggaacacc ccagctgccc aggacccagg gaactggaag ccagcaaagt tgtcctcctg       60

cccagttgtc ccggagctcc aggaagtcct ggggagaagg gagccccagg tcctcaaggg      120

ccacctggac caccaggcaa gatgggcccc aagggtgagc caggccccag aaactgccgg      180

gagctgttga gccagggcgc caccttgagc ggctggtacc atctgtgcct acctgagggc      240

agggccctcc cagtcttttg tgacatggac accgaggggg gcggctggct ggtgtttcag      300

aggcgccagg atggttctgt ggatttcttc cgctcttggt cctcctacag agcaggtttt      360

gggaaccaag agtctgaatt ctggctggga aatgagaatt tgcaccagct tactctccag      420

ggtaactggg agctgcgggt agagctggaa gactttaatg gtaaccgtac tttcgcccac      480

tatgcgacct tccgcctcct cggtgaggta gaccactacc agctggcact gggcaagttc      540

tcagagggca ctgcagggga ttccctgagc ctccacagtg ggaggccctt taccacctat      600

gacgctgacc acgattcaag caacagcaac tgtgcagtga ttgtccacgg tgcctggtgg      660

tatgcatcct gttaccgatc aaatctcaat ggtcgctatg cagtgtctga ggctgccgcc      720

cacaaatatg gcattgactg ggcctcaggc cgtggtgtgg gccaccccta ccgcagggtt      780

cggatgatgc ttcga                                                       795


<210>  4958
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  4958
atgcctgcaa atcgcctctc ttgctacaga aagatactaa aagatcacaa ctgtcacaac       60

cttccggaag gagtagctga cctgacacag attgatgtca atgtccagga tcatttctgg      120

gatgggaagg gatgtgagat gatctgttac tgcaacttca gcgaattgct ctgctgccca      180

aaagacgttt tctttggacc aaagatctct ttcgtgattc cttgcaacaa tcaa            234


<210>  4959
<211>  600
<212>  DNA
<213>  Homo Sapiens

<400>  4959
agtcccaagc aggagaagat gaagatggat tgccacaaag acgagaaagg caccatctat       60

gactatgagg ccatcgcact taataagaat gaatatgttt ccttcaagca gtatgtgggc      120

aagcacatcc tcttcgtcaa cgtggccacc tactgtggtc tgacagcgca atatcctgaa      180

ctaaatgcac tccaggagga gctgaagccc tatggtctag ttgtgttggg ctttccctgc      240

aaccaatttg gaaagcaaga accaggagat aacaaagaga ttcttcctgg gctcaagtat      300

gtccgtccag ggggaggatt tgtacctagt ttccagcttt ttgagaaagg ggatgtgaat      360

ggtgaaaaag aacagaaagt cttcagtttc ttgaagcact cctgtcctca tccctctgag      420

attttgggca cattcaaatc tatatcctgg gaccctgtaa aggtccatga catccgttgg      480

aactttgaaa agttcctggt ggggcctgat ggaatccctg tcatgcgctg gtcccaccgg      540

gctacggtca gctcagtcaa gacagacatc ctggcgtact tgaagcaatt caaaaccaaa      600


<210>  4960
<211>  1125
<212>  DNA
<213>  Homo Sapiens

<400>  4960
caatacgaac gctacagctt ccgcagcttc ccacgggacg agctgatgcc gctcgagtcg       60

gcctaccggc acgcgctgga caagtacagc ggcgagcact gggccgagag cgtgggctac      120

ctggagatca gcctgcggct gcaccgcttg ctgcgcgaca gcgaggcctt ctgccaccgc      180

aactgcagcg ccgcgccgca gcccgagccc gccgccggcc tcgccagcta tcccgagctg      240

cgcctcttcg ggggcctgct gcgccgcgcg cactgcctca agcgctgcaa gcagggcctg      300

ccagccttcc gccagtccca gcccagccgc gatgtgctgg cggacttcca gcgccgcgag      360

ccctacaagt tcctgcagtt cgcttacttc aaggcaaata atctccccaa agccatcgcc      420

gctgctcaca cctttctact gaagcatcct gatgacgaaa tgatgaagag gaacatggca      480

tattataaga gcctgcctgg tgccgaggac tacattaaag acctggaaac caagtcatat      540

gaaagcctgt tcatccgagc agtgcgggca tacaacggtg agaactggag aacatccatc      600

acagacatgg agctggccct tcccgacttc ttcaaagcct tttacgagtg tctcgcagcc      660

tgcgagggtt ccagggagat caaggacttc aaggatttct acctttccat agcagatcat      720

tatgtagaag ttctggaatg caaaatacag tgtgaagaga acctcacccc agttatagga      780

ggctatccgg ttgagaaatt tgtggctacc atgtatcatt acttgcagtt tgcctattat      840

aagttgaacg acctgaagaa tgcagccccc tgtgcagtca gctatctgct ctttgatcag      900

aatgacaagg tcatgcagca gaacctggtg tattaccagt accacaggga cacgtggggc      960

ctctcagatg agcacttcca gcccagacct gaagcagttc agttctttaa tgtgaccaca     1020

ctccagaagg agctgtatga ctttgctaag gaaaatataa tggatgatga tgagggagaa     1080

gttgtggaat atgtggatga cctcttggaa ctggaggaga ccagc                     1125


<210>  4961
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  4961
aacgagttta gtatattaaa atcaccaggg tctgttgttt tccgaaatgg aaattggcct       60

ataccaggag agcggatccc agacgtggct gcattgtcca tgggcttctc tgtgaaagaa      120

gacctttctt ggccaggact cgcagtgggt aacctgtttc atcgtcctcg ggctaccgtc      180

atggtgatgg tgaagggagt gaacaaactg gctctacccc caggcagtgt catttcgtac      240

cctttggaga atgcagttcc ttttagtctt gacagtgttg caaattccat tcactcctta      300

ttttctgagg aaactcctgt tgttttgcag ttggctccca gtgaggaaag agtgtatatg      360

gtagggaagg caaactcagt gtttgaagac ctttcagtca ccttgcgcca gctccgtaat      420

cgcctgtttc aagaaaactc tgttctcagt tcactccccc tcaattctct gagtaggaac      480

aatgaagttg acctgctctt tctttctgaa ctgcaagtgc tacatgatat ttcaagcttg      540

ctgtctcgtc ataagcatct agccaaggat cattctcctg atttatattc actggagctg      600

gcaggtttgg atgaaattgg gaagcgttat ggggaagact ctgaacaatt cagagatgct      660

tctaagatcc ttgttgacgc tctgcaaaag tttgcagatg acatgtacag tctttatggt      720

gggaatgcag tggtagagtt agtcactgtc aagtcatttg acacctccct cattaggaag      780

acaaggacta tccttgaggc aaaacaagcg aagaacccag caagtcccta taaccttgca      840

tataagtata attttgaa                                                    858


<210>  4962
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  4962
ggaaaggtgc tggtgtggcc cacagaatac agccattgga taaatatgaa gacaatcctg       60

gaagagcttg ttcagagggg tcatgaggtg attgtgttga catcttcggc ttctattctt      120

gtcaatgcca gtaaatcatc tgctattaaa ttagaagttt atcctacatc tttaactaaa      180

aatgatttgg aagatttttt tatgaaaatg ttcgatagat ggacatatag tatttcaaaa      240

aatacatttt ggtcatattt ttcacaacta caagaattgt gttgggaata ttctgactat      300

aatataaagc tctgtgaaga tgcagttttg aacaagaaac ttatgagaaa actacaagag      360

tcaaaatttg atgtccttct ggcagatgcc gttaatccct gtggtgagct gctggctgaa      420

ctacttaaca taccctttct gtacagtctc cgcttctctg ttggctacac agttgagaag      480

aatggtggag gatttctgtt ccctccttcc tatgtacctg ttgttatgtc agaattaagt      540

gatcaaatga ttttcatgga gaggataaaa aatatgatat atatgcttta ttttgacttt      600

tggtttcaag catatgatct gaagaagtgg gaccagtttt atagtgaagt tctaggaaga      660

cccactacat tatttgagac aatggggaaa gctgaaatgt ggctcattcg aacctattgg      720

gattttgaat ttcctcgccc attcttacca aatgttgatt ttgttggagg acttcactgt      780

aaaccagcca aacccttgcc taaggaaatg gaagagtttg tgcagagctc tggagaaaat      840

ggtattgtgg tgttttctct ggggtcgatg atcagtaaca tgtcagaaga aagtgccaac      900

atgattgcat cagcccttgc ccagatccca caaaaggttc tatggagatt tgatggcaag      960

aagccaaata ctttaggttc caatactcga ctgtataagt ggttacccca gaatgacctt     1020

cttggtcatc ccaaaaccaa agcttttata actcatggtg gaaccaatgg catctatgag     1080

gcgatctacc atgggatccc tatggtgggc attcccttgt ttgcggatca acatgataac     1140

attgctcaca tgaaagccaa gggagcagcc ctcagtgtgg acatcaggac catgtcaagt     1200

agagatttgc tcaatgcatt gaagtcagtc attaatgacc ctatctataa agagaatatc     1260

atgaaattat caagaattca tcatgatcaa ccggtgaagc ccctggatcg agcagtcttc     1320

tggattgagt ttgtcatgcg ccataaagga gccaagcacc ttcgggtcgc agcccacaac     1380

ctcacctgga tccagtacca ctctttggat gtg                                  1413


<210>  4963
<211>  1161
<212>  DNA
<213>  Homo Sapiens

<400>  4963
tcaagatgct cagctcaaaa aaataccgaa tttgcagtgg atctttatca agaggtttcc       60

ttatctcata aggacaacat tatattttca ccccttggaa taactttggt tcttgagatg      120

gtacaactgg gagccaaagg aaaagcacag cagcagataa gacaaacttt aaaacaacag      180

gaaacctcag ctggggaaga attttttgta ctgaagtcat ttttctctgc catctcagag      240

aaaaaacaag aatttacatt taatcttgcc aatgccctct accttcaaga aggattcact      300

gtgaaagaac agtatctcca tggcaacaag gaattttttc agagtgctat aaaactggtg      360

gattttcaag atgcaaaggc ttgtgcagag atgataagta cctgggtaga aagaaaaaca      420

gatggaaaaa ttaaagacat gttttcaggg gaagaatttg gccctctgac tcggcttgtc      480

ctggtgaatg ctatttattt caaaggagat tggaaacaga aattcagaaa agaggacaca      540

cagctgataa attttactaa gaaaaatggt tcaactgtca aaattccaat gatgaaggct      600

cttctgagaa caaaatatgg ttatttttct gaatcttccc tgaactacca agttttagaa      660

ttgtcttaca aaggtgatga atttagctta attatcatac ttcctgcaga aggtatggat      720

atagaagaag tggaaaaact aattactgct caacaaatcc taaaatggct ctctgagatg      780

caagaagagg aagtagaaat aagcctccct agatttaaag tagaacaaaa agtagacttc      840

aaagacgttt tgtattcttt gaacataacc gagatattta gtggtggctg cgacctttct      900

ggaataacag attcatctga agtgtatgtt tcccaagtga cgcaaaaagt tttctttgag      960

ataaatgaag atggtagtga agctgcaaca tcaactggca tacacatccc tgtgatcatg     1020

agtctggctc aaagccaatt tatagcaaat catccatttc tgtttattat gaagcataat     1080

ccaacagaat caattctgtt tatgggaaga gtgacaaatc ctgacaccca ggagataaaa     1140

ggaagagatt tagattcact g                                               1161


<210>  4964
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  4964
agcctcatca gtcgctgtga cttggcccag gtgctgcagc tggaggactt ggatgggttt       60

gagggttact ccctgagtga ctggctgtgc ctggcttttg tggaaagcaa gttcaacata      120

tcaaagataa atgaaaatgc agacggaagc tttgactatg gcctcttcca gatcaacagc      180

cactactggt gcaacgatta taagagttac tcggaaaacc tttgccacgt agactgtcaa      240

gatctgctga atcccaacct tcttgcaggc atccactgcg caaaaaggat tgtgtccgga      300

gcacggggga tgaacaactg ggtagaatgg aggttgcact gttcaggccg gccactcttc      360

tactggctga caggatgccg cctgaga                                          387


<210>  4965
<211>  828
<212>  DNA
<213>  Homo Sapiens

<400>  4965
atggacagct cccgggaacc gactctgggg cgcttggacg ccgctggctt ctggcaggtc       60

tggcagcgct ttgatgcgga tgaaaaaggt tacatagaag agaaggaact cgatgctttc      120

tttctccaca tgttgatgaa actgggtact gatgacacgg tcatgaaagc aaatttgcac      180

aaggtgaaac agcagtttat gactacccaa gatgcctcta aagatggtcg cattcggatg      240

aaagagcttg ctggtatgtt cttatctgag gatgaaaact ttcttctgct ctttcgccgg      300

gaaaacccac tggacagcag cgtggagttt atgcagattt ggcgcaaata tgacgctgac      360

agcagtggct ttatatcagc tgctgagctc cgcaacttcc tccgagacct ctttcttcac      420

cacaaaaagg ccatttctga ggctaaactg gaagaataca ctggcaccat gatgaagatt      480

tttgacagaa ataaagatgg tcggttggat ctaaatgact tagcaaggat tctggctctt      540

caggaaaact tccttctcca atttaaaatg gatgcttgtt ctactgaaga aaggaaaagg      600

gactttgaga aaatctttgc ctactatgat gttagtaaaa caggagccct ggaaggccca      660

gaagtggatg ggtttgtcaa agacatgatg gagcttgtcc agcccagcat cagcggggtg      720

gaccttgata agttccgcga gattctcctg cgtcactgcg acgtgaacaa ggatggaaaa      780

attcagaagt ctgagctggc tttgtgtctt gggctgaaaa tcaaccca                   828


<210>  4966
<211>  834
<212>  DNA
<213>  Homo Sapiens

<400>  4966
accgacgcca ccaacccacc cgagggtccc caagacagga gctcccagca gaaaggccgc       60

ctgtccctgc agaatacagc ggagatccag cactgtttgg tcaacgctgg cgatgtgggg      120

tgtggcgtgt ttgaatgttt cgagaacaac tcttgtgaga ttcggggctt acatgggatt      180

tgcatgactt ttctgcacaa cgctggaaaa tttgatgccc agggcaagtc attcatcaaa      240

gacgccttga aatgtaaggc ccacgctctg cggcacaggt tcggctgcat aagccggaag      300

tgcccggcca tcagggaaat ggtgtcccag ttgcagcggg aatgctacct caagcacgac      360

ctgtgcgcgg ctgcccagga gaacacccgg gtgatagtgg agatgatcca tttcaaggac      420

ttgctgctgc acgaacccta cgtggacctc gtgaacttgc tgctgacctg tggggaggag      480

gtgaaggagg ccatcaccca cagcgtgcag gttcagtgtg agcagaactg gggaagcctg      540

tgctccatct tgagcttctg cacctcggcc atccagaagc ctcccacggc gccccccgag      600

cgccagcccc aggtggacag aaccaagctc tccagggccc accacgggga agcaggacat      660

cacctcccag agcccagcag tagggagact ggccgaggtg ccaagggtga gcgaggtagc      720

aagagccacc caaacgccca tgcccgaggc agagtcgggg gccttggggc tcagggacct      780

tccggaagca gcgagtggga agacgaacag tctgagtatt ctgatatccg gagg            834


<210>  4967
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  4967
cagctgtgcc cgacaccatg tacctgcccc tggccacctc cccgatgccc gctgggagta       60

cccctggtgc tggatggctg tggctgctgc cgggtatgtg cacggcggct gggggagccc      120

tgcgaccaac tccacgtctg cgacgccagc cagggcctgg tctgccagcc cggggcagga      180

cccggtggac ggggggccct gtgcctcttg gcagaggacg acagcagctg tgaggtgaac      240

ggccgcctgt atcgggaagg ggagaccttc cagccccact gcagcatccg ctgccgctgc      300

gaggacggcg gcttcacctg cgtgccgctg tgcagcgagg atgtgcggct gcccagctgg      360

gactgccccc accccaggag ggtcgaggtc ctgggcaagt gctgccctga gtgggtgtgc      420

ggccaaggag ggggactggg gacccagccc cttccagccc aaggacccca gttttctggc      480

cttgtctctt ccctgccccc tggtgtcccc tgcccagaat ggagcacggc ctggggaccc      540

tgctcgacca cctgtgggct gggcatggcc acccgggtgt ccaaccagaa ccgcttctgc      600

cgactggaga cccagcgccg cctgtgcctg tccaggccct gcccaccctc caggggtcgc      660

agtccacaaa acagtgcctt c                                                681


<210>  4968
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  4968
ctgatagcga ccccggagca ccgctgccgg gtgccggacg ccgcgaacct gagcagcgcc       60

tggcgcaacc acactgtccc actgcggctg cgggacggcc gcgaggtgcc ccacagctgc      120

cgccgctacc ggctcgccac catcgccaac ttctcggcgc ttgggctgga gccggggcgc      180

gacgtggacc tggggcagct ggagcaggag agctgtccgg atggctggga gttcagtcag      240

gacgtctacc tgtccaccat tgtgaccgag tggaacctgg tgtgtgagga cgactggaag      300

gcc                                                                    303


<210>  4969
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  4969
gaggctcccg tgcaggaaga gaagctgtca gcaagcacct caaatttgcc atgctggctg       60

gtggaagagt ttgtggtagc agaagagtgc tctccatgct ctaatttccg ggctaaaact      120

acccctgagt gtggtcccac aggatatgta gagaaaatca catgcagctc atctaagaga      180

aatgagttca aaagctgccg ctcagctttg atggaacaac gctta                      225


<210>  4970
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  4970
accttgaact cggttctcaa ttccaacgct atcaagaacc tgcccccacc gctgggcggc       60

gctgcggggc acccaggctc tgcagtcagc gccgcgccgg gaatcctgta cccgggcggg      120

aataagtacc agaccattga caactaccag ccgtacccgt gcgcagagga cgaggagtgc      180

ggcactgatg agtactgcgc tagtcccacc cgcggagggg acgcaggcgt gcaaatctgt      240

ctcgcctgca ggaagcgccg aaaacgctgc atgcgtcacg ctatgtgctg ccccgggaat      300

tactgcaaaa atggaatatg tgtgtcttct gatcaaaatc atttccgagg agaaattgag      360

gaaaccatca ctgaaagctt tggtaatgat catagcacct tggatgggta ttccagaaga      420

accaccttgt cttcaaaaat gtatcacacc aaaggacaag aaggttctgt ttgtctccgg      480

tcatcagact gtgcctcagg attgtgttgt gctagacact tctggtccaa gatctgtaaa      540

cctgtcctga aagaaggtca agtgtgtacc aagcatagga gaaaaggctc tcatggacta      600

gaaatattcc agcgttgtta ctgtggagaa ggtctgtctt gccggataca gaaagatcac      660

catcaagcca gtaattcttc taggcttcac acttgtcaga gacac                      705


<210>  4971
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  4971
ttctttatcg gctgctccag ccaccagatt gcgggcatca cacaccagac cagtgcccac       60

cctgggctgg agctgtctcc aagctgcatg gaggcctgct cctgcccatt ggacggcttt      120

aaccctgtct gcgaccccag cactcgtgtg gaatacatca caccctgcca cgcaggctgc      180

tcaagctggg tggtccagga tgctctggac aacagccagg ttttctacac caactgcagc      240

tgcgtggtgg agggcaaccc cgtgctggca ggatcctgcg actcaacgtg cagccatctg      300

gtggtgccct tc                                                          312


<210>  4972
<211>  2463
<212>  DNA
<213>  Homo Sapiens

<400>  4972
gcgcgagtta acaagcacaa gccctggctg gagcccacct accacggcat agtcacagag       60

aacgacaaca ccgtgctcct cgacccccca ctgatcgcgc tggataaaga tgcgcctctg      120

cgatttgcag gtgagatttg tggatttaaa attcacgggc agaatgtccc ctttgatgca      180

gtggtagtgg ataaatccac tggtgaggga gtcattcgct ccaaagagaa actggactgt      240

gagctgcaga aagactattc attcaccatc caggcctatg attgtgggaa gggacctgat      300

ggcaccaacg tgaaaaagtc tcataaagca actgttcata ttcaggtgaa cgacgtgaat      360

gagtacgcgc ccgtgttcaa ggagaagtcc tacaaagcca cggtcatcga ggggaagcag      420

tacgacagca ttttgagggt ggaggccgtg gatgccgact gctcccctca gttcagccag      480

atttgcagct acgaaatcat cactccagac gtgcccttta ctgttgacaa agatggttat      540

ataaaaaaca cagagaaatt aaactacggg aaagaacatc aatataagct gaccgtcact      600

gcctatgact gtgggaagaa aagagccaca gaagatgttt tggtgaagat cagcattaag      660

ccaacctgca cccctgggtg gcaaggatgg aacaacagga ttgagtatga gccgggcacc      720

ggcgcgttgg ccgtctttcc aaatatccac ctggagacat gtgacgagcc agtcgcctca      780

gtacaggcca cagtggagct agaaaccagc cacataggga aaggctgcga ccgagacacc      840

tactcagaga agtccctcca ccggctctgt ggtgcggccg cgggcactgc cgagctgctg      900

ccatccccga gtggatccct caactggacc atgggcctgc ccaccgacaa tggccacgac      960

agcgaccagg tgtttgagtt caacggcacc caggcagtga ggatcccgga tggcgtcgtg     1020

tcggtcagcc ccaaagagcc gttcaccatc tcggtgtgga tgagacatgg gccattcggc     1080

aggaagaagg agacaattct ttgcagttct gataaaacag atatgaatcg gcaccactac     1140

tccctctatg tccacgggtg ccggctgatc ttcctcttcc gtcaggatcc ttctgaggag     1200

aagaaataca gacctgcaga gttccactgg aagttgaatc aggtctgtga tgaggaatgg     1260

caccactacg tcctcaatgt agaattcccg agtgtgactc tctatgcgga tggcacgtcc     1320

cacgagccct tctctgtgac tgaggattac ccgctccatc catccaagat agaaactcag     1380

ctcgtggtgg gggcttgctg gcaagagttt tcaggagttg aaaatgacaa tgaaactgag     1440

cctgtgactg tggcctgtgc aggtggcgac ctgcacatga cccagttttt ccgaggcaat     1500

ctggctggct taactctccg ttccgggaaa ctcgcggata agaaggtgat cgactgtctg     1560

tatacctgca aggaggggct ggacctgcag gtcctcgaag acagtggcag aggcgtgcag     1620

atccaagcac accgcagcca gttggtattg accttggagg gagaagacct cggggaattg     1680

gataaggcca tgcagcacat ctcgtacctg aactcccggc agttccccac gcccggaatt     1740

cgcagactca aaatcaccag cacaatcaag tgttttaacg aggccacctg catttcggtc     1800

cccccggtag atggctacgt gatggtttta cagcccgagg agcccaagat cagcctgagt     1860

ggcgtccacc attttgcccg agcagcttct gaatttgaaa gctcagaagg ggtgttcctt     1920

ttccctgagc ttcgcatcat cagcaccatc acgagagaag tggagcctga aggggacggg     1980

gctgaggacc ccacagttca agaatcactg gtgtccgagg agatcgtgca cgacctggat     2040

acctgtgagg tcacggtgga gggagaggag ctgaaccacg agcaggagag cctggaggtg     2100

gacatggccc gcctgcagca gaagggcatt gaagtgagca gctctgaact gggcatgacc     2160

ttcacaggcg tggacaccat ggccagctac gaggaggttt tgcacctgct gcgctatcgg     2220

aactggcatg ccaggtcctt gcttgaccgg aagtttaagc tcatctgctc agagctgaat     2280

ggccgctaca tcagcaacga atttaaggtg gaggtgaatg taatccacac ggccaacccc     2340

atggaacacg ccaaccacat ggctgcccag ccacagttcg tgcacccgga acaccgctcc     2400

tttgttgacc tgtcaggcca caacctggcc aacccccacc cgttcgcagt cgtccacagc     2460

act                                                                   2463


<210>  4973
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  4973
aaggaagtgg tgcatgccac ggaggggctg gattgggaag acaaagatgc tccagggacg       60

ttggtcggca acgtggtgca ctcaaggatc atcagtcccc tgcgcctgtt tgttaaacag      120

tctccggtgc ccaagcccgg ccccatggcg tatgcagaca gcatggaaaa cttttgggat      180

tggctggcca acatcacgga gattcaggag ccattggcaa gaactaaacg gaggccaata      240

gtaaaaacag gaaaatttaa gaaaatgttt ggatggggtg actttcattc caacattaaa      300

actgtcaaac tcaatctcct catcacaggg aaaattgttg accatggaaa tggaaccttc      360

agagtgtatt tccgacataa ttcaacaggc ctgggcaatg tttcagtgag cttggtacca      420

ccctccaagg tggtggaatt tgaagtttcc ccccagtcta ccttggagac caaggaatcc      480

aaatctttca attgtcgcat tgagtatgaa aaaacagatc gggcgaaaaa gaccgccctg      540

tgcaactttg acccatccaa gatctgctac caggagcaga ctcagagcca tgtgtcttgg      600

ttgtgctcca agcccttcaa ggtcatttgc atttacattg ccttttacag tgttgattat      660

aaactcgtgc aaaaggtgtg ccctgactac aattaccata gtgagacccc atacttatct      720

tctggc                                                                 726


<210>  4974
<211>  690
<212>  DNA
<213>  Homo Sapiens

<400>  4974
caggatgatg gtcctcccgg ctcagaggac cctgagcgtg atgaccacga gggccagccc       60

cggccccggg tgcctcggaa gcggggccac atctcaccta agtcacgccc catggccaat      120

tccactctcc tagggctgct ggccccgcct ggggaggctt ggggcattct tgggcagccc      180

cccaaccgcc cgaaccacag ccccccaccc tcagccaagg tgaagaaaat ctttggctgg      240

ggcgacttct actccaacat caagacggtg gccctgaacc tgctcgtcac agggaagatt      300

gtggaccatg gcaatgggac cttcagcgtc cacttccaac acaatgccac aggccaggga      360

aacatctcca tcagcctcgt gccccccagt aaagctgtag agttccacca ggaacagcag      420

atcttcatcg aagccaaggc ctccaaaatc ttcaactgcc ggatggggtg ggagaaggta      480

gaacggggcc gccggacctc gctttgcacc cacgacccag ccaagatctg ctcccgagac      540

cacgctcaga gctcagccac ctggagctgc tcccagccct tcaaagtcgt ctgtgtctac      600

atcgccttct acagcacgga ctatcggctg gtccagaagg tgtgcccaga ttacaactac      660

catagtgata ccccctacta cccatctggg                                       690


<210>  4975
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  4975
cagataccag agtccggaag gccgcagtac ctggggctgc gccccgccgc ggccggagcg       60

ggtgcccccg gccagcagct cccagagcca aggtcttcgg acggcctagg cgtgggccgc      120

gcctggagct gggcctggcc gaccaaccac acgggggcgc tggcccgggc aggggcagcc      180

ggggcgttgc ccgcgcagcg caccaagagg aagccgtcca tcaaggcggc gcgcgccaaa      240

aagatcttcg gctgggggga cttctacttt cgggtgcata ccctcaagtt ttcgctgctg      300

gtgaccggca agatcgtgga ccatgtgaac ggtaccttca gtgtgtattt ccgccacaac      360

tcgtccagcc tgggcaacct cagtgtcagc atcgtgccgc cctccaagcg tgtcgagttc      420

ggaggagtct ggctgcccgg gcctgtcccc caccctctgc agtctacgct cgccctggag      480

ggggtgcttc ctgggctggg gcccccgctg gggatggcag cagcagcggc ggggccgggg      540

cttgggggct ccctcggggg cgcactggcg gggccgcttg ggggcgcgtt gggagtgcct      600

ggggccaaag agtcacgcgc tttcaattgc cacgtggagt atgagaagac aaaccgcgcg      660

cgcaagcacc gaccgtgcct gtacgatcca tcgcaggtgt gcttcaccga gcacacgcag      720

agccaggccg cctggctctg tgccaagccc ttcaaagtca tctgtatctt cgtctctttc      780

ctcagctttg actacaaact ggtgcagaag gtgtgcccag actataactt ccagagtgag      840

cacccctact tcgga                                                       855


<210>  4976
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  4976
acagatacac atcatcccca ggattctgct ctgtatcatc tcagcaagca gctattacag       60

aaatatcata aagaagtgag acctgtttac aactggacca aggccaccac agtctacctg      120

gacctgttcg tccatgctat attggatgtg gatgcagaga atcaaatatt aaagacaagt      180

gtatggtacc aagaggtctg gaatgatgaa tttttatcct ggaactccag catgtttgat      240

gagattagag agatctccct acctctaagt gccatctggg cccccgatat catcatcaat      300

gagtttgtgg acattgaaag ataccctgac cttccctatg tttatgtgaa ctcatctggg      360

accattgaga actataagcc catccaggtg gtctctgcgt gcagtttaga gacatatgct      420

tttccatttg atgtccagaa ttgcagcctg accttcaaga gcattctgca tacagtggaa      480

gacgtagacc tggcctttct gaggagccca gaagacattc agcatgacaa aaaggcgttt      540

ttgaatgaca gtgagtggga acttctatct gtgtcctcca catacagcat cctgcagagc      600

agcgctggag gatttgcaca gattcagttt aatgtggtga tgcgcaggca c               651


<210>  4977
<211>  1638
<212>  DNA
<213>  Homo Sapiens

<400>  4977
gcgcccgtgg cgggcctggg ctccgacgcg gagctgcaga tcgagcggcg cttcgtgccc       60

gacgagtgcc cgcgcaccgt gcgcagcggc gacttcgtgc gctaccacta cgtggggacg      120

ttccccgacg gccagaagtt cgactccagc tatgacagag actccacttt caatgtgttt      180

gtgggaaaag gacagctgat cacagggatg gaccaggctc ttgttgggat gtgcgtaaac      240

gagagacgtt tcgtgaagat tcccccaaag cttgcctacg gaaatgaagg agtttctggt      300

gtgatccccc ccaattcagt gcttcatttt gatgtacttc tgatggatat ttggaattct      360

gaagaccagg ttcagattca cacctatttc aagcccccga gttgccctcg gaccatccag      420

gtgtctgatt ttgtgaggta ccactacaac gggacgttcc tggacggaac tctgtttgat      480

tcgagtcaca atcgcatgaa aacatatgac acgtatgtgg gaattggctg gctgattcct      540

ggaatggata aagggctgct ggggatgtgt gtgggtgaga agcgcatcat caccattcct      600

ccttttctgg cctatggaga ggatggagat gggaaagaca ttcccggtca ggcatctctg      660

gtgtttgatg ttgcattatt ggacctccat aaccccaagg acagcatttc cattgagaac      720

aaggtagtac ctgaaaactg tgagcggata agtcaaagtg gggactttct caggtatcat      780

tacaatggca cgcttctgga tggcaccctc tttgattcca gctactctcg gaaccgcacg      840

tttgacacgt acattgggca gggctacgtg attcctggga tggatgaagg tctacttggt      900

gtttgcattg gagaaaagcg aaggattgtg gtcccgcctc acctggggta tggagaggaa      960

ggaagaggga atatccccgg ctcggctgtg ctggtgtttg acatccatgt gatcgacttc     1020

cacaaccctt cggactccat cagcatcacc tcccactaca aaccccctga ctgctcagtg     1080

ctgagtaaga agggagatta cctcaaatat cactacaatg cctcacttct ggatgggacc     1140

ctgctggact ccacgtggaa tttaggcaaa acttacaata ttgttctggg atctgggcaa     1200

gttgtgttgg ggatggacat gggtctcaga gagatgtgcg ttggcgagaa acggacagtg     1260

atcattccgc ctcacctggg ctatggggaa gctggcgtgg atggagaagt gcccggcagt     1320

gccgtattag tgtttgacat tgagctgctg gagctggtgg ctggccttcc tgaggggtac     1380

atgttcatat ggaatggtga ggtgtcaccc aacctctttg aagaaattga caaggatggc     1440

aacggagaag tcctcctgga agagttctca gagtacattc acgcccaggt ggcatctggc     1500

aaagggaaac tcgctcctgg ctttgatgct gagctgattg tgaagaatat gttcaccaac     1560

caggaccgga atggagatgg gaaggtcaca gccgaggaat ttaaactcaa agaccaggaa     1620

gccaaacacg atgaactc                                                   1638


<210>  4978
<211>  993
<212>  DNA
<213>  Homo Sapiens

<400>  4978
actggaccat tagatacaac acctgaagga aggcctggag aagtgtcaga tgcacctcag       60

cgtaaacagt tttgtcactg gccctgcaaa tgccctcagc agaagccccg ttgccctcct      120

ggagtgagcc tggtgagaga tggctgtgga tgctgtaaaa tctgtgccaa gcaaccaggg      180

gaaatctgca atgaagctga cctctgtgac ccacacaaag ggctgtattg tgactactca      240

gtagacaggc ctaggtacga gactggagtg tgtgcatacc ttgtagctgt tgggtgcgag      300

ttcaaccagg tacattatca taatggccaa gtgtttcagc ccaacccctt gttcagctgc      360

ctctgtgtga gtggggccat tggatgcaca cctctgttca taccaaagct ggctggcagt      420

cactgctctg gagctaaagg tggaaagaag tctgatcagt caaactgtag cctggaacca      480

ttactacagc agctttcaac aagctacaaa acaatgccag cttatagaaa tctcccactt      540

atttggaaaa aaaaatgtct tgtgcaagca acaaaatgga ctccctgctc cagaacatgt      600

gggatgggaa tatctaacag ggtgaccaat gaaaacagca actgtgaaat gagaaaagag      660

aaaagactgt gttacattca gccttgcgac agcaatatat taaagacaat aaagattccc      720

aaaggaaaaa catgccaacc tactttccaa ctctccaaag ctgaaaaatt tgtcttttct      780

ggatgctcaa gtactcagag ttacaaaccc actttttgtg gaatatgctt ggataagaga      840

tgctgtatcc ctaataagtc taaaatgatt actattcaat ttgattgccc aaatgagggg      900

tcatttaaat ggaagatgct gtggattaca tcttgtgtgt gtcagagaaa ctgcagagaa      960

cctggagata tattttctga gctcaagatt ctg                                   993


<210>  4979
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  4979
gtggaggtgg ccacccatta cctcgagatc ataacccagc ttatagtgga gagcttccac       60

ttcaagaatg gagaagatgc cccagatctt ctgaaagtca tcactaagcc cttcacaaag      120

ctcattgtcc agctggataa aaaagttatc agccaaattg caatgaacga tgaaaaagcg      180

aaaaacaaga gtcttgtcaa gatttggtgc aaaactttta ccaacaagac ccagattaac      240

gtcactgttc cctcgactgc taactgcacc tccccttccc tctgttggac ggatggcatc      300

caaaactgga ccatgaagaa tgtgacctac aaggagaaca tcgccaaatg ccagcatatc      360

tttgtgaatt tccacctccc ggatctt                                          387


<210>  4980
<211>  564
<212>  DNA
<213>  Homo Sapiens

<400>  4980
atgttccacc aaatttgggc agctctgctc tacttctatg gtattatcct taactccatc       60

taccagtgcc ctgagcacag tcaactgaca actctgggcg tggatgggaa ggagttccca      120

gaggtccact tgggccagtg gtactttatc gcaggggcag ctcccaccaa ggaggagttg      180

gcaacttttg accctgtgga caacattgtc ttcaatatgg ctgctggctc tgccccgatg      240

cagctccacc ttcgtgctac catccgcatg aaagatgggc tctgtgtgcc ccggaaatgg      300

atctaccacc tgactgaagg gagcacagat ctcagaactg aaggccgccc tgacatgaag      360

actgagctct tttccagctc atgcccaggt ggaatcatgc tgaatgagac aggccagggt      420

taccagcgct ttctcctcta caatcgctca ccacatcctc ccgaaaagtg tgtggaggaa      480

ttcaagtccc tgacttcctg cctggactcc aaagccttct tattgactcc taggaatcaa      540

gaggcctgtg agctgtccaa taac                                             564


<210>  4981
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4981
cagtggcaga tgagctccta tgcgggtgac aacatcatca cggcccaggc catgtacaag       60

gggctgtgga tggactgcgt cacgcagagc acggggatga tgagctgcaa aatgtacgac      120

tcggtgctcg ccctgtccgc ggccttgcag gccactcga                             159


<210>  4982
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4982
ctgtggaagg tgaccgcctt catcggcaac agcatcgtgg tggcccaggt ggtgtgggag       60

ggcctgtgga tgtcctgcgt ggtgcagagc acgggccaga tgcagtgcaa ggtgtacgac      120

tcactgctgg ctctgccgca ggacctgcag gccgcacgt                             159


<210>  4983
<211>  1410
<212>  DNA
<213>  Homo Sapiens

<400>  4983
caggacactt tcactgcagc tgtttatgag catgcagcga tattgcccaa tgccacccta       60

acaccagtgt ctcgtgagga ggctttggca ttaatgaatc ggaatctgga cattttggaa      120

ggagcgatca catcagcagc agatcagggt gcgcatatta ttgtgactcc agaagatgct      180

atttatggct ggaacttcaa cagggactct ctctacccat atttggagga catcccagac      240

cctgaagtaa actggatccc ctgtaataat cgtaacagat ttggccagac cccagtacaa      300

gaaagactca gctgcctggc caagaacaac tctatctatg ttgtggcaaa tattggggac      360

aagaagccat gcgataccag tgatcctcag tgtccccctg atggccgtta ccaatacaac      420

actgatgtgg tatttgattc tcaaggaaaa ctggtggcac gctaccataa gcaaaacctt      480

ttcatgggtg aaaatcaatt caatgtaccc aaggagcctg agattgtgac tttcaatacc      540

acctttggaa gttttggcat tttcacatgc tttgatatac tcttccatga tcctgctgtt      600

accttggtga aagatttcca cgtggacacc atagtattcc caacagcttg gatgaatgtt      660

ttgccacatt tgtcagctgt tgaattccac tcagcttggg ctatgggcat gagggtcaat      720

ttccttgcat ccaacataca ttacccctca aagaaaatga caggaagtgg catctatgca      780

cccaattctt caagagcatt tcattatgat atgaagacag aagagggaaa actcctcctc      840

tcgcaactgg attcccaccc atcccattct gcagtggtga actggacttc ctatgccagc      900

agtatagaag cgctctcatc aggaaacaag gaatttaaag gcactgtctt tttcgatgaa      960

ttcacttttg tgaagctcac aggagttgca ggaaattata cagtttgtca gaaagatctc     1020

tgctgtcatt taagctacaa aatgtctgag aacataccaa atgaagtgta cgctctaggg     1080

gcatttgacg gactgcacac tgtggaaggg cgctattatc tacagatttg taccctgttg     1140

aaatgtaaaa cgactaattt aaacacttgc ggtgactcag ctgaaacagc ttctaccagg     1200

tttgaaatgt tctccctcag tggcactttc ggaacccagt atgtctttcc tgaggtgttg     1260

ctgagtgaaa atcagcttgc acctggagaa tttcaggtgt caactgacgg acgcttgttt     1320

agtctgaagc caacatccgg acctgtctta acagtaactc tgtttgggag gttgtatgag     1380

aaggactggg catcaaatgc ttcatcaggc                                      1410


<210>  4984
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  4984
caggacagtt ttatagctgc agtgtatgaa catgctgtca ttttgccaaa taaaacagaa       60

acaccagttt ctcaggagga tgccttgaat ctcatgaacg agaatataga cattctggag      120

acagcgatca agcaggcagc tgagcagggt gctcgaatca ttgtgactcc agaagatgca      180

ctttatggat ggaaatttac cagggaaact gttttccctt atctggagga tatcccagac      240

cctcaggtga actggattcc gtgtcaagac ccccacagat ttggtcacac accagtacaa      300

gcaagactca gctgcctggc caaggacaac tctatctatg tcttggcaaa tttgggggac      360

aaaaagccat gtaattcccg tgactccaca tgtcctccta atggctactt tcaatacaat      420

accaatgtgg tgtataatac agaaggaaaa ctcgtggcac gttaccataa gtaccacctg      480

tactctgagc ctcagtttaa tgtccctgaa aagccggagt tggtgacttt caacaccgca      540

tttggaaggt ttggcatttt cacgtgcttt gatatattct tctatgatcc tggtgttacc      600

ctggtgaaag atttccatgt ggacaccata ctgtttccca cagcttggat gaacgttttg      660

ccccttttga cagctattga attccattca gcttgggcaa tgggaatggg agttaatctt      720

cttgtggcca acacacatca tgtcagccta aatatgacag gaagtggtat ttatgcacca      780

aatggtccca aagtgtatca ttatgacatg aagacagagt tgggaaaact tctcctttca      840

gaggtggatt cacatcccct atcctcgctt gcctacccaa cagctgttaa ttggaatgcc      900

tacgccacca ccatcaaacc atttccagta cagaaaaaca ctttcagggg atttatttcc      960

agggatgggt tcaacttcac agaacttttt gaaaatgcag gaaaccttac agtctgtcaa     1020

aaggagcttt gctgtcattt aagctacaga atgttacaaa aagaagagaa tgaagtatac     1080

gttctaggag cttttacagg attacatggc cgaaggagaa gagagtactg gcaggtctgc     1140

acaatgctga agtgcaaaac tactaatttg acaacttgtg gacggccagt agaaactgct     1200

tctacaagat ttgaaatgtt ctccctcagt ggcacatttg gaacagagta tgtttttcct     1260

gaagtgctac ttaccgaaat tcatctgtca cctggaaaat ttgaggtgct gaaagatggg     1320

cgtttggtaa acaagaatgg atcatctggg cctatactaa cagtgtcact ctttgggagg     1380

tggtacacaa aggactcact ttacagctca tgt                                  1413


<210>  4985
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4985
cactggcgga ggacagcgca cgtgggcacc aacatcctca cggccgtgtc ctacctgaaa       60

gggctctgga tggagtgtgt gtggcacagc acaggcatct accagtgcca gatctaccga      120

tccctgctgg cgctgcccca agacctccag gctgcccgc                             159


<210>  4986
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  4986
gccagcgtgc ccctggcggc cagcccggcg cgggcgctgc ccggcggcgc cgacaatgct       60

tcggtcgcct cgggcgccgc cgcgtccccg ggcccgcagc ggagcctgag cgcgctgcac      120

ggcgcgggcg gttcagccgg gccccccgcg ctgcccgggg cacccgcggc cagcgcgcac      180

ccgctgccgc ccgggcccct gttcagccgc ttcctgtgca cgccgctggc tgctgcctgc      240

ccgtcggggg cccagcaggg ggacgcggcg ggcgctgcgc cgggcgagcg cgaagagctg      300

ctgctgctgc agagcacggc cgagcagctg cgccagacgg cgctgcagca ggaggcgcgc      360

atccgcgccg accaggacac catccgtgag ctcaccggca agctgggccg ctgcgagagc      420

ggcctgccgc gcggcctcca gggcgccggg ccccgccgcg acaccatggc cgacgggccc      480

tgggactcgc ctgcgctcat tctggagctg gaggacgccg tgcgcgccct gcgggaccgc      540

atcgaccgcc tggagcagga gcttccagcc cgtgtgaacc tctcagctgc cccagcccca      600

gtctctgctg tgcccaccgg cctacactcc aagatggacc agctggaggg gcagctgctg      660

gcccaggtgc tggcactgga gaaggagcgt gtggccctca gccacagcag ccgccggcag      720

aggcaggaag tggaaaagga gttggacgtc ctgcagggtc gtgtggctga gctggagcac      780

gggtcctcag cctacagtcc tccagatgcc ttcaagatca gcatccccat ccgtaacaac      840

tacatgtacg cccgcgtgcg gaaggctctg cccgagctct acgcattcac cgcctgcatg      900

tggctgcggt ccaggtccag cggcaccggc cagggcaccc ccttctccta ctcagtgccc      960

gggcaggcca acgagattgt actgctagag gcgggccatg agcccatgga gctgctgatc     1020

aacgacaagg tggcccagct gcccctgagc ctgaaggaca atggctggca ccacatctgc     1080

atcgcctgga ccacaaggga tggcctatgg tctgcctacc aggacgggga gctgcagggc     1140

tccggtgaga acctggctgc ctggcacccc atcaagcctc atgggatcct tatcttgggc     1200

caggagcagg ataccctggg tggccggttt gatgccaccc aggcctttgt cggtgacatt     1260

gcccagttta acctgtggga ccacgccctg acaccagccc aggtcctggg cattgccaac     1320

tgcactgcgc cactgctggg caacgtcctt ccctgggaag acaagttggt ggaggccttt     1380

gggggtgcaa caaaggctgc cttcgatgtc tgcaagggga gggccaaggc a              1431


<210>  4987
<211>  285
<212>  DNA
<213>  Homo Sapiens

<400>  4987
gccgtgccca tggactcagg cccaagctgt ctggctgtgc ccaatgccac cgggcagaca       60

ggcctccctg gagactctgg cctgctgcag gactcctctc tacctcccat tccaaggacc      120

aatgaggacc aaagggagcc aatcttgtcc actgctaaga aaaccaagcc ccatcccaga      180

tctggagacc cctcagcccc tcctcggctg gccctgagct ctgccctccc tgggccccct      240

ctgcccgctc gggggcatgc actgctgcgc tggaccgcac tgctg                      285


<210>  4988
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4988
aactccaggg acctgctggg ctgcttggca caggagcaca acatcagcgc gagccaggtc       60

aacgcgtgtc acgtggcgga gtcggccgtc aactacagcc tgggcgatga gcagggcttc      120

tgtggcagcc cctggcccaa ctgcaacttc cccgagtac                             159


<210>  4989
<211>  426
<212>  DNA
<213>  Homo Sapiens

<400>  4989
ggcggcggtg ggaaagcctg gcccacacac gtggtctgta gcgacagcgg cttggaagtg       60

ctctaccaga gttgcgatcc attacaagat tttggctttt ctgttgaaaa gtgttccaag      120

caattaaaat caaatatcaa cattagattt ggaattattc tgagagagga catcaaagag      180

ctttttcttg acctagctct catgtctcaa ggctcatctg ttttgaattt ctcctatccc      240

atctgtgagg cggctctgcc caagttttct ttctgtggaa gaaggaaagg agagcagatt      300

tactatgctg ggcctgtcaa taatcctgaa tttactattc ctcagggaga ataccaggtt      360

ttgctggaac tgtacactga aaaacggtcc accgtggcct gtgccaatgc tactatcatg      420

tgctcc                                                                 426


<210>  4990
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  4990
acacggcacc aggatggccg ccagaatcag agttctcttt cccccgtact cctgccaagg       60

aatcaaagag agcttcccac aggcaaccat gaggaagctg aggagaagcc agatctgttt      120

gtcgcagtgc cacaccttgt aggcaccagc cctgcagggg aaggccagag gcagagagag      180

aagatgctgt ccagatttgg caggttctgg aagaagcctg agagagaaat gcatccatcc      240

agggactcag atagtgagcc cttcccacct gggacccagt ctctcatcca gccgatagat      300

ggaatgaaaa tggagaaatc tcctcttcgg gaagaagcca agaaattctg gcaccacttc      360

atgttcagaa aaactccggc ttctcagggg gtcatcttgc ccatcaaaag ccatgaagta      420

cattgggaga cctgcaggac agtgcccttc agccagacta taacccacga aggctgtgag      480

aaagtagttg ttcagaacaa cctttgcttt gggaaatgcg ggtctgttca ttttcctgga      540

gccgcgcagc actcccatac ctcctgctct cactgtttgc ctgccaagtt caccacgatg      600

cacttgccac tgaactgcac tgaactttcc tccgtgatca aggtggtgat gctggtggag      660

gagtgccagt gcaaggtgaa gacggagcat gaagatggac acatcctaca tgctggctcc      720

caggattcct ttatcccagg agtttcagct                                       750


<210>  4991
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  4991
cagtggagga tttactccta tgccggcgac aacatcgtga ccgcccaggc catgtacgag       60

gggctgtgga tgtcctgcgt gtcgcagagc accgggcaga tccagtgcaa agtctttgac      120

tccttgctga atctgagcag cacattgcaa gcaacccgt                             159


<210>  4992
<211>  438
<212>  DNA
<213>  Homo Sapiens

<400>  4992
cataatgggc ttggaaaggg ttttggagat catattcatt ggaggacact ggaagatggg       60

aagaaagaag cagctgccag tggactgccc ctgatggtga ttattcataa atcctggtgt      120

ggagcttgca aagctctaaa gcccaaattt gcagaatcta cggaaatttc agaactctcc      180

cataattttg ttatggtaaa tcttgaggat gaagaggaac ccaaagatga agatttcagc      240

cctgacgggg gttatattcc acgaatcctt tttctggatc ccagtggcaa ggtgcatcct      300

gaaatcatca atgagaatgg aaaccccagc tacaagtatt tttatgtcag tgccgagcaa      360

gttgttcagg ggatgaagga agctcaggaa aggctgacgg gtgatgcctt cagaaagaaa      420

catcttgaag atgaattg                                                    438


<210>  4993
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  4993
cagactctct tccagaaccc agaagagggc tggcagctgt acacctcagc ccaggcccct       60

gacgggaaat gcatctgcac ggccgtgatc ccagcgcaga gtacctgctc tcgagatggc      120

aggagtcggg agctgcggca actgatggag aaggtccaga acgtctccca gtccatggag      180

gtccttgagt tgcggacgta tcgcgacctc cagtatgtac gcggcatgga gaccctcatg      240

cggagcctgg atgcgcggct ccgggcagct gatgggtccc tctcggccaa gagcttccag      300

gagctgaagg acaggatgac ggaactgttg cccctgagct cggtcctgga gcagtacaag      360

gcagacacgc ggaccattgt acgcttgcgg gaggaggtga ggaatctctc cggcagtctg      420

gcggccattc aggaggagat gggtgcctac gggtatgagg acctgcagca acgggtgatg      480

gccctggagg cccggctcca cgcctgcgcc cagaagctgg gctgtgggaa gctgaccggg      540

gtcagtaacc ccatcaccgt tcgggccatg gggtcccgct tcggctcctg gatgactgac      600

acgatggccc ccagtgcgga tagccgggtc tggtacatgg atggctatta caaaggccgc      660

cgggtcctgg agttccgtac cctgggagac ttcatcaaag gccagaactt tatccagcac      720

ctgctgcccc agccgtgggc gggcacgggc cacgtggtgt acaacggctc cctgttctat      780

aacaagtacc agagcaacgt ggtggtcaaa taccacttcc gctcgcgctc tgtgctggtg      840

cagaggagcc tcccgggcgc cggttacaac aacaccttcc cctactcctg gggcggcttc      900

tccgacatgg acttcatggt ggacgagagc gggctctggg ctgtgtacac caccaaccag      960

aacgcgggca acatcgtggt cagccggctg gacccgcaca ccctcgaggt catgcggtcc     1020

tgggacaccg gctaccccaa gcgcagcgct ggcgaggcct tcatgatctg cggtgtgctc     1080

tacgtgacca actcccacct ggctggggcc aaggtctact tcgcctattt taccaacacg     1140

tccagttacg agtacacgga cgtgcccttc cacaaccagt attcccacat ctcgatgctg     1200

gattacaacc cccgggagcg cgccctctat acctggaaca acggccacca ggtgctctac     1260

aatgtcaccc tgtttcacgt catcagcacc tctggggacc cc                        1302


<210>  4994
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  4994
cctggtctga ctgattggtt atttcccagg agatgtccca aaatcagaga agaatgtgaa       60

ttccaagaaa gggatgtgtg tacaaaggac agacaatgcc aggacaacaa gaagtgttgt      120

gtcttcagct gcggaaaaaa atgtttagat ctcaaacaag atgtatgcga aatgccaaaa      180

gaaactggcc cctgcctggc ttattttctt cattggtggt atgacaagaa agataatact      240

tgctccatgt ttgtctatgg tggctgccag ggaaacaata acaacttcca atccaaagcc      300

aactgcctga acacctgcaa gaataaacgc tttccc                                336


<210>  4995
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  4995
gtggtctgcc aagctcttgg ttctgaaatc acaggcttct tattagctgg aaaacctgtg       60

ttcaagttcc aacttgccaa atttaaggca cctctggaag ctgttgcagc caagatggaa      120

gtgaagaaat gcgtggatac gatggcctat gagaaaagag tgctaattac aaaaacattg      180

ggaaaaatag cagagaaatg tgatcgc                                          207


<210>  4996
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  4996
gagttctgcc cagctcttgt ttctgagctg ttagacttct tcttcattag tgaacctctg       60

ttcaagttaa gtcttgccaa atttgatgcc cctccggaag ctgttgcagc caagttagga      120

gtgaagagat gcacggatca gatgtccctt cagaaacgaa gcctcattgc ggaagtcctg      180

gtgaaaatat tgaagaaatg tagtgtg                                          207


<210>  4997
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  4997
agagatacca cagtcaaacc tggagccaaa aaggacacaa aggactctcg acccaaactg       60

ccccagaccc tctccagagg ttggggtgac caactcatct ggactcagac atatgaagaa      120

gctctatata aatccaagac aagcaacaaa cccttgatga ttattcatca cttggatgag      180

tgcccacaca gtcaagcttt aaagaaagtg tttgctgaaa ataaagaaat ccagaaattg      240

gcagagcagt ttgtcctcct caatctggtt tatgaaacaa ctgacaaaca cctttctcct      300

gatggccagt atgtccccag gattatgttt gttgacccat ctctgacagt tagagccgat      360

atcactggaa gatattcaaa ccgtctctat gcttacgaac ctgcagatac agctctgttg      420

cttgacaaca tgaagaaagc tctcaagttg ctgaagactg aattg                      465


<210>  4998
<211>  1059
<212>  DNA
<213>  Homo Sapiens

<400>  4998
gcggcggcgc aggaggcgga cggggcccgc agcgccgtgg tggcggccgg gggaggcagc       60

tccggtcagg tgaccagcaa tggcagcatc gggagggacc cgccagcgga gacccagcct      120

cagaacccac cggcccagcc ggcacccaat gcctggcagg tcatcaaagg tgtgctgttt      180

aggatcttca tcatctgggc catcagcagt tggttccgcc gagggccggc ccctcaggac      240

caggcgggcc ccggaggagc cccacgcgtc gccagccgca acctgttccc caaagacact      300

ttaatgaacc tgcatgtgta catctcagag cacgagcact ttacagactt caacgccacg      360

tcggcactct tctgggaaca gcacgatctt gtgtatggcg actggactag cggcgagaac      420

tcagacggct gctacgagca ctttgctgag ctcgatatcc cacagagcgt ccagcagaac      480

ggctccatct acatccacgt ttacttcacc aagagtggct tccacccaga cccccggcag      540

aaggccctgt accgccggct tgccacagtc cacatgtccc ggatgatcaa caaatacaag      600

cgcagacgat ttcagaaaac caagaacctg ctgacaggag agacagaagc ggacccagaa      660

atgatcaaga gggctgagga ctatgggcct gtggaggtga tctcccattg gcaccccaac      720

atcaccatca acatcgtgga cgaccacacg ccgtgggtga agggcagtgt gccccctccc      780

ctggatcaat atgtgaagtt cgacgccgtg agcggtgact actatcccat catctacttc      840

aatgactact ggaacctgca gaaggactac taccccatca acgagagcct ggccagcctg      900

ccgctccgcg tctccttctg cccgctctcg ctttggcgct ggcagctcta tgctgcccag      960

agcaccaagt cgccctggaa cttcctgggt gatgagttgt acgagcagtc agatgaggag     1020

caggactcgg tgaaggtggc cctgctggag accaacccc                            1059


<210>  4999
<211>  1071
<212>  DNA
<213>  Homo Sapiens

<400>  4999
aagcccatct tcgtacctct ctcgaactac agggatgtgc agtattttgg ggaaattggg       60

ctgggaacgc ctccacaaaa cttcactgtt gcctttgaca ctggctcctc caatctctgg      120

gtcccgtcca ggagatgcca cttcttcagt gtgccctgct ggttacacca ccgatttgat      180

cccaaagcct ctagctcctt ccaggccaat gggaccaagt ttgccattca atatggaact      240

gggcgggtag atggaatcct gagcgaggac aagctgacta ttggtggaat caagggtgca      300

tcagtgattt tcggggaggc tctctgggag cccagcctgg tcttcgcttt tgcccatttt      360

gatgggatat tgggcctcgg ttttcccatt ctgtctgtgg aaggagttcg gcccccgatg      420

gatgtactgg tggagcaggg gctattggat aagcctgtct tctcctttta cctcaacagg      480

gaccctgaag agcctgatgg aggagagctg gtcctggggg gctcggaccc ggcacactac      540

atcccacccc tcaccttcgt gccagtcacg gtccccgcct actggcagat ccacatggag      600

cgtgtgaagg tgggcccagg gctgactctc tgtgccaagg gctgtgctgc catcctggat      660

acgggcacgt ccctcatcac aggacccact gaggagatcc gggccctgca tgcagccatt      720

gggggaatcc ccttgctggc tggggagtac atcatcctgt gctcggaaat cccaaagctc      780

cccgcagtct ccttccttct tgggggggtc tggtttaacc tcacggccca tgattacgtc      840

atccagacta ctcgaaatgg cgtccgcctc tgcttgtccg gtttccaggc cctggatgtc      900

cctccgcctg cagggccctt ctggatcctc ggtgacgtct tcttggggac gtatgtggcc      960

gtcttcgacc gcggggacat gaagagcagc gcccgggtgg gcctggcgcg cgctcgcact     1020

cgcggagcgg acctcggatg gggagagact gcgcaggcgc agttccccgg g              1071


<210>  5000
<211>  990
<212>  DNA
<213>  Homo Sapiens

<400>  5000
atcaagtggc tggcgctgtc caagacacca tcggccctgg cactgaacca gacgcaacac       60

tgcaagcagc tggagggtct ggtgtctgca caggtgcagc tgtgccgcag caacctggag      120

ctcatgcaca cggtggtgca cgccgcccgc gaggtcatga aggcctgtcg ccgggccttt      180

gccgacatgc gctggaactg ctcctccatt gagctcgccc ccaactattt gcttgacctg      240

gagagaggga cccgggagtc ggccttcgtg tatgcgctgt cggccgccgc catcagccac      300

gccatcgccc gggcctgcac ctccggcgac ctgcccggct gctcctgcgg ccccgtccca      360

ggtgagccac ccgggcccgg gaaccgctgg ggaggatgtg cggacaacct cagctacggg      420

ctcctcatgg gggccaagtt ttccgatgct cctatgaagg tgaaaaaaac aggatcccaa      480

gccaataaac tgatgcgtct acacaacagt gaagtgggga gacaggctct gcgcgcctct      540

ctggaaatga agtgtaagtg ccatggggtg tctggctcct gctccatccg cacctgctgg      600

aaggggctgc aggagctgca ggatgtggct gctgacctca agacccgata cctgtcggcc      660

accaaggtag tgcaccgacc catgggcacc cgcaagcacc tggtgcccaa ggacctggat      720

atccggcctg tgaaggactc ggaactcgtc tatctgcaga gctcacctga cttcagcatg      780

aagaatgaga aggtgggctc ccacgggaca caagacaggc agtgcaacaa gacatccaac      840

ggaagcgaca gctgcgacct tatgtgctgc gggcgtggct acaaccccta cacagaccgc      900

gtggtcgagc ggtgccactg taagtaccac tggtgctgct acgtcacctg ccgcaggtgt      960

gagcgtaccg tggagcgcta tgtctgcaag                                       990


<210>  5001
<211>  3138
<212>  DNA
<213>  Homo Sapiens

<400>  5001
aaagaaaagc attattacat tggaattatt gaaacgactt gggattatgc ctctgaccat       60

ggggaaaaga aacttatttc tgttgacacg gaacattcca atatctatct tcaaaatggc      120

ccagatagaa ttgggagact atataagaag gccctttatc ttcagtacac agatgaaacc      180

tttaggacaa ctatagaaaa accggtctgg cttgggtttt taggccctat tatcaaagct      240

gaaactggag ataaagttta tgtacactta aaaaaccttg cctctaggcc ctacaccttt      300

cattcacatg gaataactta ctataaggaa catgaggggg ccatctaccc tgataacacc      360

acagattttc aaagagcaga tgacaaagta tatccaggag agcagtatac atacatgttg      420

cttgccactg aagaacaaag tcctggggaa ggagatggca attgtgtgac taggatttac      480

cattcccaca ttgatgctcc aaaagatatt gcctcaggac tcatcggacc tttaataatc      540

tgtaaaaaag attctctaga taaagaaaaa gaaaaacata ttgaccgaga atttgtggtg      600

atgttttctg tggtggatga aaatttcagc tggtacctag aagacaacat taaaacctac      660

tgctcagaac cagagaaagt tgacaaagac aacgaagact tccaggagag taacagaatg      720

tattctgtga atggatacac ttttggaagt ctcccaggac tctccatgtg tgctgaagac      780

agagtaaaat ggtacctttt tggtatgggt aatgaagttg atgtgcacgc agctttcttt      840

cacgggcaag cactgactaa caagaactac cgtattgaca caatcaacct ctttcctgct      900

accctgtttg atgcttatat ggtggcccag aaccctggag aatggatgct cagctgtcag      960

aatctaaacc atctgaaagc cggtttgcaa gcctttttcc aggtccagga gtgtaacaag     1020

tcttcatcaa aggataatat ccgtgggaag catgttagac actactacat tgccgctgag     1080

gaaatcatct ggaactatgc tccctctggt atagacatct tcactaaaga aaacttaaca     1140

gcacctggaa gtgactcagc ggtgtttttt gaacaaggta ccacaagaat tggaggctct     1200

tataaaaagc tggtttatcg tgagtacaca gatgcctcct tcacaaatcg aaaggagaga     1260

ggccctgaag aagagcatct tggcatcctg ggtcctgtca tttgggcaga ggtgggagac     1320

accatcagag taaccttcca taacaaagga gcatatcccc tcagtattga gccgattggg     1380

gtgagattca ataagaacaa cgagggcaca tactattccc caaattacaa cccccagagc     1440

agaagtgtgc ctccttcagc ctcccatgtg gcacccacag aaacattcac ctatgaatgg     1500

actgtcccca aagaagtagg acccactaat gcagatcctg tgtgtctagc taagatgtat     1560

tattctgctg tggatcccac taaagatata ttcactgggc ttattgggcc aatgaaaata     1620

tgcaagaaag gaagtttaca tgcaaatggg agacagaaag atgtagacaa ggaattctat     1680

ttgtttccta cagtatttga tgagaatgag agtttactcc tggaagataa tattagaatg     1740

tttacaactg cacctgatca ggtggataag gaagatgaag actttcagga atctaataaa     1800

atgcactcca tgaatggatt catgtatggg aatcagccgg gtctcactat gtgcaaagga     1860

gattcggtcg tgtggtactt attcagcgcc ggaaatgagg ccgatgtaca tggaatatac     1920

ttttcaggaa acacatatct gtggagagga gaacggagag acacagcaaa cctcttccct     1980

caaacaagtc ttacgctcca catgtggcct gacacagagg ggacttttaa tgttgaatgc     2040

cttacaactg atcattacac aggcggcatg aagcaaaaat atactgtgaa ccaatgcagg     2100

cggcagtctg aggattccac cttctacctg ggagagagga catactatat cgcagcagtg     2160

gaggtggaat gggattattc cccacaaagg gagtgggaaa aggagctgca tcatttacaa     2220

gagcagaatg tttcaaatgc atttttagat aagggagagt tttacatagg ctcaaagtac     2280

aagaaagttg tgtatcggca gtatactgat agcacattcc gtgttccagt ggagagaaaa     2340

gctgaagaag aacatctggg aattctaggt ccacaacttc atgcagatgt tggagacaaa     2400

gtcaaaatta tctttaaaaa catggccaca aggccctact caatacatgc ccatggggta     2460

caaacagaga gttctacagt tactccaaca ttaccaggtg aaactctcac ttacgtatgg     2520

aaaatcccag aaagatctgg agctggaaca gaggattctg cttgtattcc atgggcttat     2580

tattcaactg tggatcaagt taaggacctc tacagtggat taattggccc cctgattgtt     2640

tgtcgaagac cttacttgaa agtattcaat cccagaagga aactggaatt tgcccttctg     2700

tttctagttt ttgatgagaa tgaatcttgg tacttagatg acaacatcaa aacatactct     2760

gatcaccccg agaaagtaaa caaagatgat gaggaattca tagaaagcaa taaaatgcat     2820

gctattaatg gaagaatgtt tggaaaccta caaggcctca caatgcacgt gggagatgaa     2880

gtcaactggt atctgatggg aatgggcaat gaaatagact tacacactgt acattttcac     2940

ggccatagct tccaatacaa gcacagggga gtttatagtt ctgatgtctt tgacattttc     3000

cctggaacat accaaaccct agaaatgttt ccaagaacac ctggaatttg gttactccac     3060

tgccatgtga ccgaccacat tcatgctgga atggaaacca cttacaccgt tctacaaaat     3120

gaagacacca aatctggc                                                   3138


<210>  5002
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5002
aagcaattca caaaatgtga gctgtcccag ctgctgaaag acatagatgg ttatggaggc       60

atcgctttgc ctgaattgat ctgtaccatg tttcacacca gtggttatga cacacaagcc      120

atagttgaaa acaatgaaag cacggaatat ggactcttcc agatcagtaa taagctttgg      180

tgcaagagca gccaggtccc tcagtcaagg aacatctgtg acatctcctg tgacaagttc      240

ctggatgatg acattactga tgacataatg tgtgccaaga agatcctgga tattaaagga      300

attgactact ggttggccca taaagccctc tgcactgaga agctggaaca gtggctttgt      360

gagaagttg                                                              369


<210>  5003
<211>  1737
<212>  DNA
<213>  Homo Sapiens

<400>  5003
gccaacacct tcttggagga ggtgcgcaag ggcaacctgg agcgagagtg cgtggaggag       60

acgtgcagct acgaggaggc cttcgaggct ctggagtcct ccacggctac ggatgtgttc      120

tgggccaagt acacagcttg tgagacagcg aggacgcctc gagataagct tgctgcatgt      180

ctggaaggta actgtgctga gggtctgggt acgaactacc gagggcatgt gaacatcacc      240

cggtcaggca ttgagtgcca gctatggagg agtcgctacc cacataagcc tgaaatcaac      300

tccactaccc atcctggggc cgacctacag gagaatttct gccgcaaccc cgacagcagc      360

accacgggac cctggtgcta cactacagac cccaccgtga ggaggcagga atgcagcatc      420

cctgtctgtg gccaggatca agtcactgta gcgatgactc cacgctccga aggctccagt      480

gtgaatctgt cacctccatt ggagcagtgt gtccctgatc gggggcagca gtaccagggg      540

cgcctggcgg tgaccacaca tgggctcccc tgcctggcct gggccagcgc acaggccaag      600

gccctgagca agcaccagga cttcaactca gctgtgcagc tggtggagaa cttctgccgc      660

aacccagacg gggatgagga gggcgcgtgg tgctatgtgg ccgggaagcc tggcgacttt      720

gggtactgcg acctcaacta ttgtgaggag gccgtggagg aggagacagg agatgggctg      780

gatgaggact cagacagggc catcgaaggg cgtaccgcca ccagtgagta ccagactttc      840

ttcaatccga ggacctttgg ctcgggagag gcagactgtg ggctgcgacc tctgttcgag      900

aagaagtcgc tggaggacaa aaccgaaaga gagctcctgg aatcctacat cgacgggcgc      960

attgtggagg gctcggatgc agagatcggc atgtcacctt ggcaggtgat gcttttccgg     1020

aagagtcccc aggagctgct gtgtggggcc agcctcatca gtgaccgctg ggtcctcacc     1080

gccgcccact gcctcctgta cccgccctgg gacaagaact tcaccgagaa tgaccttctg     1140

gtgcgcattg gcaagcactc ccgcaccagg tacgagcgaa acattgaaaa gatatccatg     1200

ttggaaaaga tctacatcca ccccaggtac aactggcggg agaacctgga ccgggacatt     1260

gccctgatga agctgaagaa gcctgttgcc ttcagtgact acattcaccc tgtgtgtctg     1320

cccgacaggg agacggcagc cagcttgctc caggctggat acaaggggcg ggtgacaggc     1380

tggggcaacc tgaaggagac gtggacagcc aacgttggta aggggcagcc cagtgtcctg     1440

caggtggtga acctgcccat tgtggagcgg ccggtctgca aggactccac ccggatccgc     1500

atcactgaca acatgttctg tgctggttac aagcctgatg aagggaaacg aggggatgcc     1560

tgtgaaggtg acagtggggg accctttgtc atgaagagcc cctttaacaa ccgctggtat     1620

caaatgggca tcgtctcatg gggtgaaggc tgtgaccggg atgggaaata tggcttctac     1680

acacatgtgt tccgcctgaa gaagtggata cagaaggtca ttgatcagtt tggagag        1737


<210>  5004
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5004
actccatggt ctttggcctg gccccaggga tcctgctctc tggagggggt agagatcaaa       60

ggcggctcct tccgacttct ccaagagggc caggcactgg agtacgtgtg tccttctggc      120

ttctacccgt accctgtgca gacacgtacc tgcagatcta cggggtcctg gagcaccctg      180

aagactcaag accaaaagac tgtcaggaag gcagagtgca gagcaatcca ctgtccaaga      240

ccacacgact tcgagaacgg ggaatactgg ccccggtctc cctactacaa tgtgagtgat      300

gagatctctt tccactgcta tgacggttac actctccggg gctctgccaa tcgcacctgc      360

caagtgaatg gccggtggag tgggcagaca gcgatctgtg acaacggagc ggggtactgc      420

tccaacccgg gcatccccat tggcacaagg aaggtgggca gccagtaccg ccttgaagac      480

agcgtcacct accactgcag ccgggggctt accctgcgtg gctcccagcg gcgaacgtgt      540

caggaaggtg gctcttggag cgggacggag ccttcctgcc aagactcctt catgtacgac      600

acccctcaag aggtggccga agctttcctg tcttccctga cagagaccat agaaggagtc      660

gatgctgagg atgggcacgg cccaggggaa caacagaagc gg                         702


<210>  5005
<211>  1020
<212>  DNA
<213>  Homo Sapiens

<400>  5005
ctgacacttg gcaacaccac ctcctccgtg atcctcacca actacatgga cacccagtac       60

tatggcgaga ttggcatcgg caccccaccc cagaccttca aagtcgtctt tgacactggt      120

tcgtccaatg tttgggtgcc ctcctccaag tgcagccgtc tctacactgc ctgtgtgtat      180

cacaagctct tcgatgcttc ggattcctcc agctacaagc acaatggaac agaactcacc      240

ctccgctatt caacagggac agtcagtggc tttctcagcc aggacatcat caccgtgggt      300

ggaatcacgg tgacacagat gtttggagag gtcacggaga tgcccgcctt acccttcatg      360

ctggccgagt ttgatggggt tgtgggcatg ggcttcattg aacaggccat tggcagggtc      420

acccctatct tcgacaacat catctcccaa ggggtgctaa aagaggacgt cttctctttc      480

tactacaaca gagattccga gaattcccaa tcgctgggag gacagattgt gctgggaggc      540

agcgaccccc agcattacga agggaatttc cactatatca acctcatcaa gactggtgtc      600

tggcagattc aaatgaaggg ggtgtctgtg gggtcatcca ccttgctctg tgaagacggc      660

tgcctggcat tggtagacac cggtgcatcc tacatctcag gttctaccag ctccatagag      720

aagctcatgg aggccttggg agccaagaag aggctgtttg attatgtcgt gaagtgtaac      780

gagggcccta cactccccga catctctttc cacctgggag gcaaagaata cacgctcacc      840

agcgcggact atgtatttca ggaatcctac agtagtaaaa agctgtgcac actggccatc      900

cacgccatgg atatcccgcc acccactgga cccacctggg ccctgggggc caccttcatc      960

cgaaagttct acacagagtt tgatcggcgt aacaaccgca ttggcttcgc cttggcccgc     1020


<210>  5006
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  5006
gactccctgg gaagagaggc caaatgttac aatgaactta atggatgcac caagatatat       60

gaccctgtct gtgggactga tggaaatact tatcccaatg aatgcgtgtt atgttttgaa      120

aatcggaaac gccagacttc tatcctcatt caaaaatctg ggccttgc                   168


<210>  5007
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  5007
gaggatcccc agggagatgc tgcccagaag acagatacat cccaccatga tcaggatcac       60

ccaaccttca acaagatcac ccccaacctg gctgagttcg ccttcagcct ataccgccag      120

ctggcacacc agtccaacag caccaatatc ttcttctccc cagtgagcat cgctacagcc      180

tttgcaatgc tctccctggg gaccaaggct gacactcacg atgaaatcct ggagggcctg      240

aatttcaacc tcacggagat tccggaggct cagatccatg aaggcttcca ggaactcctc      300

cgtaccctca accagccaga cagccagctc cagctgacca ccggcaatgg cttgttcctc      360

agcgagggcc tgaagctagt ggataagttt ttggaggatg ttaaaaagtt gtaccactca      420

gaagccttca ctgtcaactt cggggacacc gaagaggcca agaaacagat caacgattac      480

gtggagaagg gtactcaagg gaaaattgtg gatttggtca aggagcttga cagagacaca      540

gtttttgctc tggtgaatta catcttcttt aaaggcaaat gggagagacc ctttgaagtc      600

aaggacaccg aggaagagga cttccacgtg gaccaggtga ccaccgtgaa ggtgcctatg      660

atgaagcgtt taggcatgtt taacatccag cactgtaaga agctgtccag ctgggtgctg      720

ctgatgaaat acctgggcaa tgccaccgcc atcttcttcc tgcctgatga ggggaaacta      780

cagcacctgg aaaatgaact cacccacgat atcatcacca agttcctgga aaatgaagac      840

agaaggtctg ccagcttaca tttacccaaa ctgtccatta ctggaaccta tgatctgaag      900

agcgtcctgg gtcaactggg catcactaag gtcttcagca atggggctga cctctccggg      960

gtcacagagg aggcacccct gaagctctcc aaggccgtgc ataaggctgt gctgaccatc     1020

gacgagaaag ggactgaagc tgctggggcc atgtttttag aggccatacc catgtctatc     1080

ccccccgagg tcaagttcaa caaacccttt gtcttcttaa tgattgacca aaataccaag     1140

tctcccctct tcatgggaaa agtggtgaat cccacccaaa aa                        1182


<210>  5008
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  5008
aacagcccac ttgacgagga gaatctgacc caggagaacc aagaccgagg gacacacgtg       60

gacctcggat tagcctccgc caacgtggac ttcgctttca gcctgtacaa gcagttagtc      120

ctgaaggccc ctgataagaa tgtcatcttc tccccactga gcatctccac cgccttggcc      180

ttcctgtctc tgggggccca taataccacc ctgacagaga ttctcaaagg cctcaagttc      240

aacctcacgg agacttctga ggcagaaatt caccagagct tccagcacct cctgcgcacc      300

ctcaatcagt ccagcgatga gctgcagctg agtatgggaa atgccatgtt tgtcaaagag      360

caactcagtc tgctggacag gttcacggag gatgccaaga ggctgtatgg ctccgaggcc      420

tttgccactg actttcagga ctcagctgca gctaagaagc tcatcaacga ctacgtgaag      480

aatggaacta gggggaaaat cacagatctg atcaaggacc ttgactcgca gacaatgatg      540

gtcctggtga attacatctt ctttaaagcc aaatgggaga tgccctttga cccccaagat      600

actcatcagt caaggttcta cttgagcaag aaaaagtggg taatggtgcc catgatgagt      660

ttgcatcacc tgactatacc ttacttccgg gacgaggagc tgtcctgcac cgtggtggag      720

ctgaagtaca caggcaatgc cagcgcactc ttcatcctcc ctgatcaaga caagatggag      780

gaagtggaag ccatgctgct cccagagacc ctgaagcggt ggagagactc tctggagttc      840

agagagatag gtgagctcta cctgccaaag ttttccatct cgagggacta taacctgaac      900

gacatacttc tccagctggg cattgaggaa gccttcacca gcaaggctga cctgtcaggg      960

atcacagggg ccaggaacct agcagtctcc caggtggtcc ataaggctgt gcttgatgta     1020

tttgaggagg gcacagaagc atctgctgcc acagcagtca aaatcaccct cctttctgca     1080

ttagtggaga caaggaccat tgtgcgtttc aacaggccct tcctgatgat cattgtccct     1140

acagacaccc agaacatctt cttcatgagc aaagtcacca atcccaagca agcc           1194


<210>  5009
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  5009
gaccgggtgt acatacaccc cttccacctc gtcatccaca atgagagtac ctgtgagcag       60

ctggcaaagg ccaatgccgg gaagcccaaa gaccccacct tcatacctgc tccaattcag      120

gccaagacat cccctgtgga tgaaaaggcc ctacaggacc agctggtgct agtcgctgca      180

aaacttgaca ccgaagacaa gttgagggcc gcaatggtcg ggatgctggc caacttcttg      240

ggcttccgta tatatggcat gcacagtgag ctatggggcg tggtccatgg ggccaccgtc      300

ctctccccaa cggctgtctt tggcaccctg gcctctctct atctgggagc cttggaccac      360

acagctgaca ggctacaggc aatcctgggt gttccttgga aggacaagaa ctgcacctcc      420

cggctggatg cgcacaaggt cctgtctgcc ctgcaggctg tacagggcct gctagtggcc      480

cagggcaggg ctgatagcca ggcccagctg ctgctgtcca cggtggtggg cgtgttcaca      540

gccccaggcc tgcacctgaa gcagccgttt gtgcagggcc tggctctcta tacccctgtg      600

gtcctcccac gctctctgga cttcacagaa ctggatgttg ctgctgagaa gattgacagg      660

ttcatgcagg ctgtgacagg atggaagact ggctgctccc tgacgggagc cagtgtggac      720

agcaccctgg ctttcaacac ctacgtccac ttccaaggga agatgaaggg cttctccctg      780

ctggccgagc cccaggagtt ctgggtggac aacagcacct cagtgtctgt tcccatgctc      840

tctggcatgg gcaccttcca gcactggagt gacatccagg acaacttctc ggtgactcaa      900

gtgtccttca ctgagagcgc ctgcctgctg ctgatccagc ctcactatgc ctctgacctg      960

gacaaggtgg agggtctcac tttccagcaa aactccctca actggatgaa gaaactgtct     1020

ccccggacca tccacctgac catgccccaa ctggtgctgc aaggatctta tgacctgcag     1080

gacctgctcg cccaggctga gctgcccgcc attctgcaca ccgagctgaa cctgcaaaaa     1140

ttgagcaatg accgcatcag ggtgggggag gtgctgaaca gcattttttt tgagcttgaa     1200

gcggatgaga gagagcccac agagtctacc caacagctta acaagcctga ggtcttggag     1260

gtgaccctga accgcccatt cctgtttgct gtgtatgatc aaagcgccac tgccctgcac     1320

ttcctgggcc gcgtggccaa cccgctgagc acagca                               1356


<210>  5010
<211>  552
<212>  DNA
<213>  Homo Sapiens

<400>  5010
tgcacctgtg tcccacccca cccacagacg gccttctgca attccgacct cgtcatcagg       60

gccaagttcg tggggacacc agaagtcaac cagaccacct tataccagcg ttatgagatc      120

aagatgacca agatgtataa agggttccaa gccttagggg atgccgctga catccggttc      180

gtctacaccc ccgccatgga gagtgtctgc ggatacttcc acaggtccca caaccgcagc      240

gaggagtttc tcattgctgg aaaactgcag gatggactct tgcacatcac tacctgcagt      300

ttcgtggctc cctggaacag cctgagctta gctcagcgcc ggggcttcac caagacctac      360

actgttggct gtgaggaatg cacagtgttt ccctgtttat ccatcccctg caaactgcag      420

agtggcactc attgcttgtg gacggaccag ctcctccaag gctctgaaaa gggcttccag      480

tcccgtcacc ttgcctgcct gcctcgggag ccagggctgt gcacctggca gtccctgcgg      540

tcccagatag cc                                                          552


<210>  5011
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  5011
tccagtcccg gcaagccgcc gcgcctggtg ggaggcccca tggacgccag cgtggaggag       60

gagggtgtgc ggcgtgcact ggactttgcc gtcggcgagt acaacaaagc cagcaacgac      120

atgtaccaca gccgcgcgct gcaggtggtg cgcgcccgca agcagatcgt agctggggtg      180

aactacttct tggacgtgga gctgggccga accacgtgta ccaagaccca gcccaacttg      240

gacaactgcc ccttccatga ccagccacat ctgaaaagga aagcattctg ctctttccag      300

atctacgctg tgccttggca gggcacaatg accttgtcga aatccacctg tcaggacgcc      360


<210>  5012
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  5012
tcgagctcca aggaggagaa taggataatc ccaggtggca tctatgatgc agacctcaat       60

gatgagtggg tacagcgtgc ccttcacttc gccatcagcg agtacaacaa ggccaccgaa      120

gatgagtact acagacgccc gctgcaggtg ctgcgagcca gggagcagac ctttgggggg      180

gtgaattact tcttcgacgt agaggtgggc cgcaccatat gtaccaagtc ccagcccaac      240

ttggacacct gtgccttcca tgaacagcca gaactgcaga agaaacagtt gtgctctttc      300

gagatctacg aagttccctg ggaggacaga atgtccctgg tgaattccag gtgtcaagaa      360

gcc                                                                    363


<210>  5013
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  5013
tggagcccca aggaggagga taggataatc ccgggtggca tctataacgc agacctcaat       60

gatgagtggg tacagcgtgc ccttcacttc gccatcagcg agtataacaa ggccaccaaa      120

gatgactact acagacgtcc gctgcgggta ctaagagcca ggcaacagac cgttgggggg      180

gtgaattact tcttcgacgt agaggtgggc cgaaccatat gtaccaagtc ccagcccaac      240

ttggacacct gtgccttcca tgaacagcca gaactgcaga agaaacagtt gtgctctttc      300

gagatctacg aagttccctg ggagaacaga aggtccctgg tgaaatccag gtgtcaagaa      360

tcc                                                                    363


<210>  5014
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  5014
cagcactggt cctatggact gcgccctgga ggaaagagag atgccgaaaa tttgattgat       60

tctttccaag agatagtcaa agaggttggt caactggcag aaacccaacg cttcgaatgc      120

accacgcacc agccacgttc tcccctccga gacctgaaag gagctctgga aagtctgatt      180

gaagaggaaa ctgggcagaa gaagatt                                          207


<210>  5015
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5015
gccgcgccgg acctcgacgt gcgcaagtgc ctcccctgcg gccccggggg caaaggccgc       60

tgcttcgggc ccaatatctg ctgcgcggaa gagctgggct gcttcgtggg caccgccgaa      120

gcgctgcgct gccaggagga gaactacctg ccgtcgccct gccagtccgg ccagaaggcg      180

tgcgggagcg ggggccgctg cgcggtcttg ggcctctgct gcagcccgga cggctgccac      240

gccgaccctg cctgcgacgc ggaagccacc ttctcccagc gc                         282


<210>  5016
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  5016
gccatgtccg acctggagct gagacagtgc ctcccctgcg gccccggggg caaaggccgc       60

tgcttcgggc ccagcatctg ctgcgcggac gagctgggct gcttcgtggg cacggctgag      120

gcgctgcgct gccaggagga gaactacctg ccgtcgccct gccagtccgg ccagaaggcg      180

tgcgggagcg ggggccgctg cgccgccttc ggcgtttgct gcaacgacga gagctgcgtg      240

accgagcccg agtgccgcga gggctttcac cgccgcgcc                             279


<210>  5017
<211>  267
<212>  DNA
<213>  Homo Sapiens

<400>  5017
gagctgactg gccagcgact ccgggaggga gatggccccg acggccctgc cgatgacggc       60

gcaggggccc aggccgacct ggagcacagc ctgctggtgg cggccgagaa gaaggacgag      120

ggcccctaca ggatggagca cttccgctgg ggcagcccgc ccaaggacaa gcgctacggc      180

ggtttcatga cctccgagaa gagccagacg cccctggtga cgctgttcaa aaacgccatc      240

atcaagaacg cctacaagaa gggcgag                                          267


<210>  5018
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  5018
ttttgtattc caactgagta tacaatgcac atcgaaagga gagagtgtgc ttattgccta       60

accatcaaca ccaccatctg tgctggatat tgtatgacac gggatatcaa tggcaaactg      120

tttcttccca aatatgctct gtcccaggat gtttgcacat atagagactt catctacagg      180

actgtagaaa taccaggatg cccactccat gttgctccct atttttccta tcctgttgct      240

ttaagctgta agtgtggcaa gtgcaatact gactatagtg actgcataca tgaagccatc      300

aagacaaact actgtaccaa acctcagaag tcttat                                336


<210>  5019
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  5019
aatagctgtg agctgaccaa catcaccatt gcaatagaga aagaagaatg tcgtttctgc       60

ataagcatca acaccacttg gtgtgctggc tactgctaca ccagggatct ggtgtataag      120

gacccagcca ggcccaaaat ccagaaaaca tgtaccttca aggaactggt atacgaaaca      180

gtgagagtgc ccggctgtgc tcaccatgca gattccttgt atacataccc agtggccacc      240

cagtgtcact gtggcaagtg tgacagcgac agcactgatt gtactgtgcg aggcctgggg      300

cccagctact gctcctttgg tgaaatgaaa gaa                                   333


<210>  5020
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  5020
ttgcccatct gtcccggcgg ggctgcccga tgccaggtga cccttcgaga cctgtttgac       60

cgcgccgtcg tcctgtccca ctacatccat aacctctcct cagaaatgtt cagcgaattc      120

gataaacggt atacccatgg ccgggggttc attaccaagg ccatcaacag ctgccacact      180

tcttcccttg ccacccccga agacaaggag caagcccaac agatgaatca aaaagacttt      240

ctgagcctga tagtcagcat attgcgatcc tggaatgagc ctctgtatca tctggtcacg      300

gaagtacgtg gtatgcaaga agccccggag gctatcctat ccaaagctgt agagattgag      360

gagcaaacca aacggcttct agagggcatg gagctgatag tcagccaggt tcatcctgaa      420

accaaagaaa atgagatcta ccctgtctgg tcgggacttc catccctgca gatggctgat      480

gaagagtctc gcctttctgc ttattataac ctgctccact gcctacgcag ggattcacat      540

aaaatcgaca attatctcaa gctcctgaag tgccgaatca tccacaacaa caactgc         597


<210>  5021
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5021
ttcccaacca ttcccttatc caggcttttt gacaacgcta tgctccgcgc ccgtcgcctg       60

taccagctgg catatgacac ctatcaggag tttgaagaag cctatatcct gaaggagcag      120

aagtattcat tcctgcagaa cccccagacc tccctctgct tctcagagtc tattccaaca      180

ccttccaaca gggtgaaaac gcagcagaaa tctaacctag agctgctccg catctccctg      240

ctgctcatcc agtcatggct ggagcccgtg cagctcctca ggagcgtctt cgccaacagc      300

ctggtgtatg gcgcctcgga cagcaacgtc tatcgccacc tgaaggacct agaggaaggc      360

atccaaacgc tgatgtggag gctggaagat ggcagccccc ggactgggca gatcttcaat      420

cagtcctaca gcaagtttga cacaaaatcg cacaacgatg acgcactgct caagaactac      480

gggctgctct actgcttcag gaaggacatg gacaaggtcg agacattcct gcgcatcgtg      540

cagtgccgct ctgtggaggg cagctgtggc ttc                                   573


<210>  5022
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  5022
cgttcccttc aagacacaga ggagaaatcc agatcattct cagcttccca ggcagaccca       60

ctcagtgatc ctgatcagat gaacgaggac aagcgccatt cacagggcac attcaccagt      120

gactacagca agtatctgga ctccaggcgt gcccaagatt ttgtgcagtg gttgatgaat      180

accaagagga acaggaataa cattgcc                                          207


<210>  5023
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  5023
tcttggaagc cccgctccca gcagccagat gcacccttag gtacaggggc caacagggac       60

ctggagctac cctggctgga gcagcagggc ccagcctctc atcatcgaag gcagctggga      120

ccccagggtc ccccacacct cgtggcagac ccgtccaaga agcagggacc atggctggag      180

gaagaagaag aagcctatgg atggatggac ttc                                   213


<210>  5024
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  5024
gatgaacccc cccagagccc ctgggatcga gtgaaggacc tggccactgt gtacgtggat       60

gtgctcaaag acagcggcag agactatgtg tcccagtttg aaggctccgc cttgggaaaa      120

cagctaaacc taaagctcct tgacaactgg gacagcgtga cctccacctt cagcaagctg      180

cgcgaacagc tcggccctgt gacccaggag ttctgggata acctggaaaa ggagacagag      240

ggcctgaggc aggagatgag caaggatctg gaggaggtga aggccaaggt gcagccctac      300

ctggacgact tccagaagaa gtggcaggag gagatggagc tctaccgcca gaaggtggag      360

ccgctgcgcg cagagctcca agagggcgcg cgccagaagc tgcacgagct gcaagagaag      420

ctgagcccac tgggcgagga gatgcgcgac cgcgcgcgcg cccatgtgga cgcgctgcgc      480

acgcatctgg ccccctacag cgacgagctg cgccagcgct tggccgcgcg ccttgaggct      540

ctcaaggaga acggcggcgc cagactggcc gagtaccacg ccaaggccac cgagcatctg      600

agcacgctca gcgagaaggc caagcccgcg ctcgaggacc tccgccaagg cctgctgccc      660

gtgctggaga gcttcaaggt cagcttcctg agcgctctcg aggagtacac taagaagctc      720

aacacccag                                                              729


<210>  5025
<211>  897
<212>  DNA
<213>  Homo Sapiens

<400>  5025
aaggtggagc aagcggtgga gacagagccg gagcccgagc tgcgccagca gaccgagtgg       60

cagagcggcc agcgctggga actggcactg ggtcgctttt gggattacct gcgctgggtg      120

cagacactgt ctgagcaggt gcaggaggag ctgctcagct cccaggtcac ccaggaactg      180

agggcgctga tggacgagac catgaaggag ttgaaggcct acaaatcgga actggaggaa      240

caactgaccc cggtggcgga ggagacgcgg gcacggctgt ccaaggagct gcaggcggcg      300

caggcccggc tgggcgcgga catggaggac gtgtgcggcc gcctggtgca gtaccgcggc      360

gaggtgcagg ccatgctcgg ccagagcacc gaggagctgc gggtgcgcct cgcctcccac      420

ctgcgcaagc tgcgtaagcg gctcctccgc gatgccgatg acctgcagaa gcgcctggca      480

gtgtaccagg ccggggcccg cgagggcgcc gagcgcggcc tcagcgccat ccgcgagcgc      540

ctggggcccc tggtggaaca gggccgcgtg cgggccgcca ctgtgggctc cctggccggc      600

cagccgctac aggagcgggc ccaggcctgg ggcgagcggc tgcgcgcgcg gatggaggag      660

atgggcagcc ggacccgcga ccgcctggac gaggtgaagg agcaggtggc ggaggtgcgc      720

gccaagctgg aggagcaggc ccagcagata cgcctgcagg ccgaggcctt ccaggcccgc      780

ctcaagagct ggttcgagcc cctggtggaa gacatgcagc gccagtgggc cgggctggtg      840

gagaaggtgc aggctgccgt gggcaccagc gccgcccctg tgcccagcga caatcac         897


<210>  5026
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5026
caggcaaagg agccatgtgt ggagagcctg gtttctcagt acttccagac cgtgactgac       60

tatggcaagg acctgatgga gaaggtcaag agcccagagc ttcaggccga ggccaagtct      120

tactttgaaa agtcaaagga gcagctgaca cccctgatca agaaggctgg aacggaactg      180

gttaacttct tgagctattt cgtggaactt ggaacacagc ctgccaccca g               231


<210>  5027
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5027
accccagacg tctccagtgc cttggataag ctgaaggagt ttggaaacac actggaggac       60

aaggctcggg aactcatcag ccgcatcaaa cagagtgaac tttctgccaa gatgcgggag      120

tggttttcag agacatttca gaaagtgaag gagaaactca agattgactc a               171


<210>  5028
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5028
gatgagatgc ctagcccgac cctcctcacc caggtgaagg aatctctctc cagttactgg       60

gagtcagcaa agacagccgc ccagaacctg tacgagaaga catacctgcc cgctgtagat      120

gagaaactca gggacttgta cagcaaaagc acagcagcca tgagcactta cacaggcatt      180

tttactgacc aagttctttc tgtgctgaag ggagaggag                             219


<210>  5029
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  5029
tcagaggccg aggatgcctc ccttctcagc ttcatgcagg gttacatgaa gcacgccacc       60

aagaccgcca aggatgcact gagcagcgtg caggagtccc aggtggccca gcaggccagg      120

ggctgggtga ccgatggctt cagttccctg aaagactact ggagcaccgt taaggacaag      180

ttctctgagt tctgggattt ggaccctgag gtcagaccaa cttcagccgt ggctgcc         237


<210>  5030
<211>  1341
<212>  DNA
<213>  Homo Sapiens

<400>  5030
ggtcatcgac cccttgacaa gaagagagaa gaggctccca gcctgaggcc tgccccaccg       60

cccatcagtg gaggtggcta tcgggctcgt ccagccaaag cagctgccac tcaaaagaaa      120

gtagaaagaa aagcccctga tgctggaggc tgtcttcacg ctgacccaga cctgggggtg      180

ttgtgtccta caggatgtca gttgcaagag gctttgctac aacaggaaag gccaatcaga      240

aatagtgttg atgagttaaa taacaatgtg gaagctgttt cccagacctc ctcttcttcc      300

tttcagtaca tgtatttgct gaaagacctg tggcaaaaga ggcagaagca agtaaaagat      360

aatgaaaatg tagtcaatga gtactcctca gaactggaaa agcaccaatt atatatagat      420

gagactgtga atagcaatat cccaactaac cttcgtgtgc ttcgttcaat cctggaaaac      480

ctgagaagca aaatacaaaa gttagaatct gatgtctcag ctcaaatgga atattgtcgc      540

accccatgca ctgtcagttg caatattcct gtggtgtctg gcaaagaatg tgaggaaatt      600

atcaggaaag gaggtgaaac atctgaaatg tatctcattc aacctgacag ttctgtcaaa      660

ccgtatagag tatactgtga catgaataca gaaaatggag gatggacagt gattcagaac      720

cgtcaagacg gtagtgttga ctttggcagg aaatgggatc catataaaca gggatttgga      780

aatgttgcaa ccaacacaga tgggaagaat tactgtggcc taccaggtga atattggctt      840

ggaaatgata aaattagcca gcttaccagg atgggaccca cagaactttt gatagaaatg      900

gaggactgga aaggagacaa agtaaaggct cactatggag gattcactgt acagaatgaa      960

gccaacaaat accagatctc agtgaacaaa tacagaggaa cagccggtaa tgccctcatg     1020

gatggagcat ctcagctgat gggagaaaac aggaccatga ccattcacaa cggcatgttc     1080

ttcagcacgt atgacagaga caatgacggc tggttaacat cagatcccag aaaacagtgt     1140

tctaaagaag acggtggtgg atggtggtat aatagatgtc atgcagccaa tccaaacggc     1200

agatactact ggggtggaca gtacacctgg gacatggcaa agcatggcac agatgatggt     1260

gtagtatgga tgaattggaa ggggtcatgg tactcaatga ggaagatgag tatgaagatc     1320

aggcccttct tcccacagca a                                               1341


<210>  5031
<211>  1233
<212>  DNA
<213>  Homo Sapiens

<400>  5031
tatgttgcta ccagagacaa ctgctgcatc ttagatgaaa gattcggtag ttattgtcca       60

actacctgtg gcattgcaga tttcctgtct acttatcaaa ccaaagtaga caaggatcta      120

cagtctttgg aagacatctt acatcaagtt gaaaacaaaa catcagaagt caaacagctg      180

ataaaagcaa tccaactcac ttataatcct gatgaatcat caaaaccaaa tatgatagac      240

gctgctactt tgaagtccag gaaaatgtta gaagaaatta tgaaatatga agcatcgatt      300

ttaacacatg actcaagtat tcgatatttg caggaaatat ataattcaaa taatcaaaag      360

attgttaacc tgaaagagaa ggtagcccag cttgaagcac agtgccagga accttgcaaa      420

gacacggtgc aaatccatga tatcactggg aaagattgtc aagacattgc caataaggga      480

gctaaacaga gcgggcttta ctttattaaa cctctgaaag ctaaccagca attcttagtc      540

tactgtgaaa tcgatgggtc tggaaatgga tggactgtgt ttcagaagag acttgatggc      600

agtgtagatt tcaagaaaaa ctggattcaa tataaagaag gatttggaca tctgtctcct      660

actggcacaa cagaattttg gctgggaaat gagaagattc atttgataag cacacagtct      720

gccatcccat atgcattaag agtggaactg gaagactgga atggcagaac cagtactgca      780

gactatgcca tgttcaaggt gggacctgaa gctgacaagt accgcctaac atatgcctac      840

ttcgctggtg gggatgctgg agatgccttt gatggctttg attttggcga tgatcctagt      900

gacaagtttt tcacatccca taatggcatg cagttcagta cctgggacaa tgacaatgat      960

aagtttgaag gcaactgtgc tgaacaggat ggatctggtt ggtggatgaa caagtgtcac     1020

gctggccatc tcaatggagt ttattaccaa ggtggcactt actcaaaagc atctactcct     1080

aatggttatg ataatggcat tatttgggcc acttggaaaa cccggtggta ttccatgaag     1140

aaaaccacta tgaagataat cccattcaac agactcacaa ttggagaagg acagcaacac     1200

cacctggggg gagccaaaca ggctggagac gtt                                  1233


<210>  5032
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  5032
ttaagtacca ctgaggtggc aatgcacact tcaacctctt cttcagtcac aaagagttac       60

atctcatcac agacaaatga tacgcacaaa cgggacacat atgcagccac tcctagagct      120

catgaagttt cagaaatttc tgttagaact gtttaccctc cagaagagga aaccggagaa      180

agggtacaac ttgcccatca tttctctgaa ccagag                                216


<210>  5033
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  5033
cagacagaca tgtcgaggaa ggcttttgtg tttcccaaag agtcggatac ttcctatgta       60

tccctcaaag caccgttaac gaagcctctc aaagccttca ctgtgtgcct ccacttctac      120

acggaactgt cctcgacccg tgggtacagt attttctcgt atgccaccaa gagacaagac      180

aatgagattc tcatattttg gtctaaggat ataggataca gttttacagt gggtgggtct      240

gaaatattat tcgaggttcc tgaagtcaca gtagctccag tacacatttg tacaagctgg      300

gagtccgcct cagggatcgt ggagttctgg gtagatggga agcccagggt gaggaagagt      360

ctgaagaagg gatacactgt gggggcagaa gcaagcatca tcttggggca ggagcaggat      420

tccttcggtg ggaactttga aggaagccag tccctggtgg gagacattgg aaatgtgaac      480

atgtgggact ttgtgctgtc accagatgag attaacacca tctatcttgg cgggcccttc      540

agtcctaatg tcctgaactg gcgggcactg aagtatgaag tgcaaggcga agtgttcacc      600

aaaccccagc tgtggccc                                                    618


<210>  5034
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  5034
cacacagacc tcagtgggaa ggtgtttgta tttcctagag aatctgttac tgatcatgta       60

aacttgatca caccgctgga gaagcctcta cagaacttta ccttgtgttt tcgagcctat      120

agtgatctct ctcgtgccta cagcctcttc tcctacaata cccaaggcag ggataatgag      180

ctactagttt ataaagaaag agttggagag tatagtctat acattggaag acacaaagtt      240

acatccaaag ttatcgaaaa gttcccggct ccagtgcaca tctgtgtgag ctgggagtcc      300

tcatcaggta ttgctgaatt ttggatcaat gggacacctt tggtgaaaaa gggtctgcga      360

cagggttact ttgtggaagc tcagcccaag attgtcctgg ggcaggaaca ggattcctat      420

gggggcaagt ttgataggag ccagtccttt gtgggagaga ttggggattt gtacatgtgg      480

gactctgtgc tgcccccaga aaatatcctg tctgcctatc agggtacccc tctccctgcc      540

aatatcctgg actggcaggc tctgaactat gaaatcagag gatatgtcat catcaaaccc      600

ttggtgtggg tc                                                          612


<210>  5035
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  5035
ggacggacct gtcccaagcc agatgattta ccattttcca cagtggtccc gttaaaaaca       60

ttctatgagc caggagaaga gattacgtat tcctgcaagc cgggctatgt gtcccgagga      120

gggatgagaa agtttatctg ccctctcaca ggactgtggc ccatcaacac tctgaaatgt      180

acacccagag tatgtccttt tgctggaatc ttagaaaatg gagccgtacg ctatacgact      240

tttgaatatc ccaacacgat cagtttttct tgtaacactg ggttttatct gaatggcgct      300

gattctgcca agtgcactga ggaaggaaaa tggagcccgg agcttcctgt ctgtgctccc      360

atcatctgcc ctccaccatc catacctacg tttgcaacac ttcgtgttta taagccatca      420

gctggaaaca attccctcta tcgggacaca gcagtttttg aatgtttgcc acaacatgcg      480

atgtttggaa atgatacaat tacctgcacg acacatggaa attggactaa attaccagaa      540

tgcagggaag taaaatgccc attcccatca agaccagaca atggatttgt gaactatcct      600

gcaaaaccaa cactttatta caaggataaa gccacatttg gctgccatga tggatattct      660

ctggatggcc cggaagaaat agaatgtacc aaactgggaa actggtctgc catgccaagt      720

tgtaaagcat cttgtaaagt acctgtgaaa aaagccactg tggtgtacca aggagagaga      780

gtaaagattc aggaaaaatt taagaatgga atgctacatg gtgataaagt ttctttcttc      840

tgcaaaaata aggaaaagaa gtgtagctat acagaggatg ctcagtgtat agatggcact      900

atcgaagtcc ccaaatgctt caaggaacac agttctctgg ctttttggaa aactgatgca      960

tccgatgtaa agccatgc                                                    978


<210>  5036
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5036
gagcgcgact gccgagtgag cagcttccga gtcaaggaga acttcgacaa ggctcgcttc       60

tctgggacct ggtacgccat ggccaagaag gaccccgagg gcctctttct gcaggacaac      120

atcgtcgcgg agttctccgt ggacgagacc ggccagatga gcgccacagc caagggccga      180

gtccgtcttt tgaataactg ggacgtgtgc gcagacatgg tgggcacctt cacagacacc      240

gaggaccctg ccaagttcaa gatgaagtac tggggcgtag cctcctttct ccagaaagga      300

aatgatgacc actggatcgt cgacacagac tacgacacgt atgccgtgca gtactcctgc      360

cgcctcctga acctcgatgg cacctgtgct gacagctact ccttcgtgtt ttcccgggac      420

cccaacggcc tgcccccaga agcgcagaag attgtaaggc agcggcagga ggagctgtgc      480

ctggccaggc agtacaggct gatcgtccac aacggttact gcgatggcag atcagaaaga      540

aaccttttg                                                              549


<210>  5037
<211>  552
<212>  DNA
<213>  Homo Sapiens

<400>  5037
ggccctgtgc caacgccgcc cgacaacatc caagtgcagg aaaacttcaa tatctctcgg       60

atctatggga agtggtacaa cctggccatc ggttccacct gcccctggct gaagaagatc      120

atggacagga tgacagtgag cacgctggtg ctgggagagg gcgctacaga ggcggagatc      180

agcatgacca gcactcgttg gcggaaaggt gtctgtgagg agacgtctgg agcttatgag      240

aaaacagata ctgatgggaa gtttctctat cacaaatcca aatggaacat aaccatggag      300

tcctatgtgg tccacaccaa ctatgatgag tatgccattt tcctgaccaa gaaattcagc      360

cgccatcatg gacccaccat tactgccaag ctctacgggc gggcgccgca gctgagggaa      420

actctcctgc aggacttcag agtggttgcc cagggtgtgg gcatccctga ggactccatc      480

ttcaccatgg ctgaccgagg tgaatgtgtc cctggggagc aggaaccaga gcccatctta      540

atcccgagag tc                                                          552


<210>  5038
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5038
cagatcccat tgtgtgccaa cctagtaccg gtgcccatca ccaacgccac cctggaccgg       60

atcactggca agtggtttta tatcgcatcg gcctttcgaa acgaggagta caataagtcg      120

gttcaggaga tccaagcaac cttcttttac ttcaccccca acaagacaga ggacacgatc      180

tttctcagag agtaccagac ccgacaggac cagtgcatct ataacaccac ctacctgaat      240

gtccagcggg aaaatgggac catctccaga tacgtgggag gccaagagca tttcgctcac      300

ttgctgatcc tcagggacac caagacctac atgcttgctt ttgacgtgaa cgatgagaag      360

aactgggggc tgtctgtcta tgctgacaag ccagagacga ccaaggagca actgggagag      420

ttctacgaag ctctcgactg cttgcgcatt cccaagtcag atgtcgtgta caccgattgg      480

aaaaaggata agtgtgagcc actggagaag cagcacgaga aggagaggaa acaggaggag      540

ggggaatcc                                                              549


<210>  5039
<211>  1047
<212>  DNA
<213>  Homo Sapiens

<400>  5039
gccccacatg gcccagggct gatttataga caaccgaact gcgatgatcc agaaactgag       60

gaagcagctc tggtggctat agactacatc aatcaaaacc ttccttgggg atacaaacac      120

accttgaacc agattgatga agtaaaggtg tggcctcagc agccctccgg agagctgttt      180

gagattgaaa tagacaccct ggaaaccacc tgccatgtgc tggaccccac ccctgtggca      240

agatgcagcg tgaggcagct gaaggagcat gctgtcgaag gagactgtga tttccagctg      300

ttgaaactag atggcaagtt ttccgtggta tacgcaaaat gtgattccag tccagactca      360

gccgaggacg tgcgcaaggt gtgccaagac tgccccctgc tggccccgct gaacgacacc      420

agggtggtgc acgccgcgaa agctgccctg gccgccttca acgctcagaa caacggctcc      480

aattttcagc tggaggaaat ttcccgggct cagcttgtgc ccctcccacc ttctacctat      540

gtggagttta cagtgtctgg cactgactgt gttgctaaag aggccacaga ggcagccaag      600

tgtaacctgc tggcagaaaa gcaatatggc ttttgtaagg caacactcag tgagaagctt      660

ggtggggcag aggttgcagt gacctgcacg gtgttccaaa cacagcccgt gacctcacag      720

ccccaaccag aaggtgccaa tgaagcagtc cccacccccg tggtggaccc agatgcacct      780

ccgtcccctc cacttggcgc acctggactc cctccagctg gctcaccccc agactcccat      840

gtgttactgg cagctcctcc aggacaccag ttgcaccggg cgcactacga cctgcgccac      900

accttcatgg gtgtggtctc attggggtca ccctcaggag aagtgtcgca cccccggaaa      960

acacgcacag tggtgcagcc tagtgttggt gctgctgctg ggccagtggt tcctccatgt     1020

ccggggagga tcagacactt caaggtc                                         1047


<210>  5040
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5040
ggccctacgg gcaccggtga atccaagtgt cctctgatgg tcaaagttct agatgctgtc       60

cgaggcagtc ctgccatcaa tgtggccgtg catgtgttca gaaaggctgc tgatgacacc      120

tgggagccat ttgcctctgg gaaaaccagt gagtctggag agctgcatgg gctcacaact      180

gaggaggaat ttgtagaagg gatatacaaa gtggaaatag acaccaaatc ttactggaag      240

gcacttggca tctccccatt ccatgagcat gcagaggtgg tattcacagc caacgactcc      300

ggcccccgcc gctacaccat tgccgccctg ctgagcccct actcctattc caccacggct      360

gtcgtcacca atcccaagga a                                                381


<210>  5041
<211>  1755
<212>  DNA
<213>  Homo Sapiens

<400>  5041
gatgcacaca agagtgaggt tgctcatcgg tttaaagatt tgggagaaga aaatttcaaa       60

gccttggtgt tgattgcctt tgctcagtat cttcagcagt gtccatttga agatcatgta      120

aaattagtga atgaagtaac tgaatttgca aaaacatgtg ttgctgatga gtcagctgaa      180

aattgtgaca aatcacttca tacccttttt ggagacaaat tatgcacagt tgcaactctt      240

cgtgaaacct atggtgaaat ggctgactgc tgtgcaaaac aagaacctga gagaaatgaa      300

tgcttcttgc aacacaaaga tgacaaccca aacctccccc gattggtgag accagaggtt      360

gatgtgatgt gcactgcttt tcatgacaat gaagagacat ttttgaaaaa atacttatat      420

gaaattgcca gaagacatcc ttacttttat gccccggaac tccttttctt tgctaaaagg      480

tataaagctg cttttacaga atgttgccaa gctgctgata aagctgcctg cctgttgcca      540

aagctcgatg aacttcggga tgaagggaag gcttcgtctg ccaaacagag actcaagtgt      600

gccagtctcc aaaaatttgg agaaagagct ttcaaagcat gggcagtagc tcgcctgagc      660

cagagatttc ccaaagctga gtttgcagaa gtttccaagt tagtgacaga tcttaccaaa      720

gtccacacgg aatgctgcca tggagatctg cttgaatgtg ctgatgacag ggcggacctt      780

gccaagtata tctgtgaaaa tcaagattcg atctccagta aactgaagga atgctgtgaa      840

aaacctctgt tggaaaaatc ccactgcatt gccgaagtgg aaaatgatga gatgcctgct      900

gacttgcctt cattagctgc tgattttgtt gaaagtaagg atgtttgcaa aaactatgct      960

gaggcaaagg atgtcttcct gggcatgttt ttgtatgaat atgcaagaag gcatcctgat     1020

tactctgtcg tgctgctgct gagacttgcc aagacatatg aaaccactct agagaagtgc     1080

tgtgccgctg cagatcctca tgaatgctat gccaaagtgt tcgatgaatt taaacctctt     1140

gtggaagagc ctcagaattt aatcaaacaa aattgtgagc tttttgagca gcttggagag     1200

tacaaattcc agaatgcgct attagttcgt tacaccaaga aagtacccca agtgtcaact     1260

ccaactcttg tagaggtctc aagaaaccta ggaaaagtgg gcagcaaatg ttgtaaacat     1320

cctgaagcaa aaagaatgcc ctgtgcagaa gactatctat ccgtggtcct gaaccagtta     1380

tgtgtgttgc atgagaaaac gccagtaagt gacagagtca ccaaatgctg cacagaatcc     1440

ttggtgaaca ggcgaccatg cttttcagct ctggaagtcg atgaaacata cgttcccaaa     1500

gagtttaatg ctgaaacgtt caccttccat gcagatatat gcacactttc tgagaaggag     1560

agacaaatca agaaacaaac tgcacttgtt gagcttgtga aacacaagcc caaggcaaca     1620

aaagagcaac tgaaagctgt tatggatgat ttcgcagctt ttgtagagaa gtgctgcaag     1680

gctgacgata aggagacctg ctttgccgag gagggtaaaa aacttgttgc tgcaagtcaa     1740

gctgccttag gctta                                                      1755


<210>  5042
<211>  1773
<212>  DNA
<213>  Homo Sapiens

<400>  5042
agaacactgc atagaaatga atatggaata gcttccatat tggattctta ccaatgtact       60

gcagagataa gtttagctga cctggctacc atattttttg cccagtttgt tcaagaagcc      120

acttacaagg aagtaagcaa aatggtgaaa gatgcattga ctgcaattga gaaacccact      180

ggagatgaac agtcttcagg gtgtttagaa aaccagctac ctgcctttct ggaagaactt      240

tgccatgaga aagaaatttt ggagaagtac ggacattcag actgctgcag ccaaagtgaa      300

gagggaagac ataactgttt tcttgcacac aaaaagccca ctccagcatc gatcccactt      360

ttccaagttc cagaacctgt cacaagctgt gaagcatatg aagaagacag ggagacattc      420

atgaacaaat tcatttatga gatagcaaga aggcatccct tcctgtatgc acctacaatt      480

cttctttggg ctgctcgcta tgacaaaata attccatctt gctgcaaagc tgaaaatgca      540

gttgaatgct tccaaacaaa ggcagcaaca gttacaaaag aattaagaga aagcagcttg      600

ttaaatcaac atgcatgtgc agtaatgaaa aattttggga cccgaacttt ccaagccata      660

actgttacta aactgagtca gaagtttacc aaagttaatt ttactgaaat ccagaaacta      720

gtcctggatg tggcccatgt acatgagcac tgttgcagag gagatgtgct ggattgtctg      780

caggatgggg aaaaaatcat gtcctacata tgttctcaac aagacactct gtcaaacaaa      840

ataacagaat gctgcaaact gaccacgctg gaacgtggtc aatgtataat tcatgcagaa      900

aatgatgaaa aacctgaagg tctatctcca aatctaaaca ggtttttagg agatagagat      960

tttaaccaat tttcttcagg ggaaaaaaat atcttcttgg caagttttgt tcatgaatat     1020

tcaagaagac atcctcagct tgctgtctca gtaattctaa gagttgctaa aggataccag     1080

gagttattgg agaagtgttt ccagactgaa aaccctcttg aatgccaaga taaaggagaa     1140

gaagaattac agaaatacat ccaggagagc caagcattgg caaagcgaag ctgcggcctc     1200

ttccagaaac taggagaata ttacttacaa aatgcgtttc tcgttgctta cacaaagaaa     1260

gccccccagc tgacctcgtc ggagctgatg gccatcacca gaaaaatggc agccacagca     1320

gccacttgtt gccaactcag tgaggacaaa ctattggcct gtggcgaggg agcggctgac     1380

attattatcg gacacttatg tatcagacat gaaatgactc cagtaaaccc tggtgttggc     1440

cagtgctgca cttcttcata tgccaacagg aggccatgct tcagcagctt ggtggtggat     1500

gaaacatatg tccctcctgc attctctgat gacaagttca ttttccataa ggatctgtgc     1560

caagctcagg gtgtagcgct gcaaacgatg aagcaagagt ttctcattaa ccttgtgaag     1620

caaaagccac aaataacaga ggaacaactt gaggctgtca ttgcagattt ctcaggcctg     1680

ttggagaaat gctgccaagg ccaggaacag gaagtctgct ttgctgaaga gggacaaaaa     1740

ctgatttcaa aaactcgtgc tgctttggga gtt                                  1773


<210>  5043
<211>  1374
<212>  DNA
<213>  Homo Sapiens

<400>  5043
ttagagagag gccgggatta tgaaaagaat aaagtctgca aggaattctc ccatctggga       60

aaggaggact tcacatctct gtcactagtc ctgtacagta gaaaatttcc cagtggcacg      120

tttgaacagg tcagccaact tgtgaaggaa gttgtctcct tgaccgaagc ctgctgtgcg      180

gaaggggctg accctgactg ctatgacacc aggacctcag cactgtctgc caagtcctgt      240

gaaagtaatt ctccattccc cgttcaccca ggcactgctg agtgctgcac caaagagggc      300

ctggaacgaa agctctgcat ggctgctctg aaacaccagc cacaggaatt ccctacctac      360

gtggaaccca caaatgatga aatctgtgag gcgttcagga aagatccaaa ggaatatgct      420

aatcaattta tgtgggaata ttccactaat tacggacaag ctcctctgtc acttttagtc      480

agttacacca agagttatct ttctatggta gggtcctgct gtacctctgc aagcccaact      540

gtatgctttt tgaaagagag actccagctt aaacatttat cacttctcac cactctgtca      600

aatagagtct gctcacaata tgctgcttat ggggagaaga aatcaaggct cagcaatctc      660

ataaagttag cccaaaaagt gcctactgct gatctggagg atgttttgcc actagctgaa      720

gatattacta acatcctctc caaatgctgt gagtctgcct ctgaagattg catggccaaa      780

gagctgcctg aacacacagt aaaactctgt gacaatttat ccacaaagaa ttctaagttt      840

gaagactgtt gtcaagaaaa aacagccatg gacgtttttg tgtgcactta cttcatgcca      900

gctgcccaac tccccgagct tccagatgta gagttgccca caaacaaaga tgtgtgtgat      960

ccaggaaaca ccaaagtcat ggataagtat acatttgaac taagcagaag gactcatctt     1020

ccggaagtat tcctcagtaa ggtacttgag ccaaccctaa aaagccttgg tgaatgctgt     1080

gatgttgaag actcaactac ctgttttaat gctaagggcc ctctactaaa gaaggaacta     1140

tcttctttca ttgacaaggg acaagaacta tgtgcagatt attcagaaaa tacatttact     1200

gagtacaaga aaaaactggc agagcgacta aaagcaaaat tgcctgatgc cacacccacg     1260

gaactggcaa agctggttaa caagcgctca gactttgcct ccaactgctg ttccataaac     1320

tcacctcctc tttactgtga ttcagagatt gatgctgaat tgaagaatat cctg           1374


<210>  5044
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  5044
caggacttag atgaagatgt cagccaagaa gacgttccct tggtaatatc agatggagga       60

gactctgagc agttcataga tgaggagcgt cagggaccac ctttgggagg acagcaatct      120

caaccctctg ctggtgatgg gaaccaggat gatggccctc agcagggacc accccaacaa      180

ggaggccagc agcaacaagg tccaccacct cctcagggaa agccacaagg accaccccaa      240

cagggaggcc atccccctcc tcctcaagga aggccacaag gaccacccca acagggaggc      300

catccccgtc ctcctcgagg aaggccacaa ggaccacccc aacagggagg ccatcagcaa      360

ggtcctcccc cacctcctcc tggaaagccc cagggaccac ctccccaagg gggccgccca      420

caaggacctc cacaggggca gtctcctcag                                       450


<210>  5045
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5045
caaagaggcc ccaggggacc atatccacct ggaccgctgg ctcctcctca accttttggc       60

ccaggatttg ttccaccacc tcctcctcca ccctatggtc cagggagaat cccacctcct      120

cctcccgcac cctatggtcc agggatattt ccaccacccc ctcctcaacc c               171


<210>  5046
<211>  147
<212>  DNA
<213>  Homo Sapiens

<400>  5046
tacctgtatc aatggctggg agccccagtc ccctacccgg atcccctgga gcccaggagg       60

gaggtgtgtg agctcaatcc ggactgtgac gagttggctg accacatcgg ctttcaggag      120

gcctatcggc gcttctacgg cccggtc                                          147


<210>  5047
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5047
caggataact ccaggtacac acacttcctg acccagcact atgatgccaa accacagggc       60

cgggatgaca gatactgtga aagcatcatg aggagacggg gcctgacctc accctgcaaa      120

gacatcaaca catttattca tggcaacaag cgcagcatca aggccatctg tgaaaacaag      180

aatggaaacc ctcacagaga aaacctaaga ataagcaagt cttctttcca ggtcaccact      240

tgcaagctac atggaggttc cccctggcct ccatgccagt accgagccac agcggggttc      300

agaaacgttg ttgttgcttg tgaaaatggc ttacctgtcc acttggatca gtcaattttc      360

cgtcgtccg                                                              369


<210>  5048
<211>  1821
<212>  DNA
<213>  Homo Sapiens

<400>  5048
gaatgtgtga ctcagttgtt gaaggacacc tgctttgaag gaggggacat tactacggtc       60

ttcacaccaa gcgccaagta ctgccaggta gtctgcactt accacccaag atgtttactc      120

ttcactttca cggcggaatc accatctgag gatcccaccc gatggtttac ttgtgtcctg      180

aaagacagtg ttacagaaac actgccaaga gtgaatagga cagcagcgat ttctgggtat      240

tctttcaagc aatgctcaca ccaaataagc gcttgcaaca aagacattta tgtggaccta      300

gacatgaagg gcataaacta taacagctca gttgccaaga gtgctcaaga atgccaagaa      360

agatgcacgg atgacgtcca ctgccacttt ttcacgtacg ccacaaggca gtttcccagc      420

ctggagcatc gtaacatttg tctactgaag cacacccaaa cagggacacc aaccagaata      480

acgaagctcg ataaagtggt gtctggattt tcactgaaat cctgtgcact ttctaatctg      540

gcttgtatta gggacatttt ccctaatacg gtgtttgcag acagcaacat cgacagtgtc      600

atggctcccg atgcttttgt ctgtggccga atctgcactc atcatcccgg ttgcttgttt      660

tttaccttct tttcccagga atggcccaaa gaatctcaaa gaaatctttg tctccttaaa      720

acatctgaga gtggattgcc cagtacacgc attaaaaaga gcaaagctct ttctggtttc      780

agtctacaaa gctgcaggca cagcatccca gtgttctgcc attcttcatt ttaccatgac      840

actgatttct tgggagaaga actggatatt gttgctgcaa aaagtcacga ggcctgccag      900

aaactgtgca ccaatgccgt ccgctgccag ttttttacct ataccccagc ccaagcatcc      960

tgcaacgaag ggaagggcaa gtgttactta aagctttctt caaacggatc tccaactaaa     1020

atacttcacg ggagaggagg catctctgga tacacattaa ggttgtgtaa aatggataat     1080

gagtgtacca ccaaaatcaa gcccaggatc gttggaggaa ctgcgtctgt tcgtggtgag     1140

tggccgtggc aggtgaccct gcacacaacc tcacccactc agagacacct gtgtggaggc     1200

tccatcattg gaaaccagtg gatattaaca gccgctcact gtttctatgg ggtagagtca     1260

cctaagattt tgcgtgtcta cagtggcatt ttaaatcaat ctgaaataaa agaggacaca     1320

tctttctttg gggttcaaga aataataatc catgatcagt ataaaatggc agaaagcggg     1380

tatgatattg ccttgttgaa actggaaacc acagtgaatt acacagattc tcaacgaccc     1440

atatgcctgc cttccaaagg agatagaaat gtaatataca ctgattgctg ggtgactgga     1500

tgggggtaca gaaaactaag agacaaaata caaaatactc tccagaaagc caagataccc     1560

ttagtgacca acgaagagtg ccagaagaga tacagaggac ataaaataac ccataagatg     1620

atctgtgccg gctacaggga aggagggaag gacgcttgca agggagattc gggaggccct     1680

ctgtcctgca aacacaatga ggtctggcat ctggtaggca tcacgagctg gggcgaaggc     1740

tgtgctcaaa gggagcggcc aggtgtttac accaacgtgg tcgagtacgt ggactggatt     1800

ctggagaaaa ctcaagcagt g                                               1821


<210>  5049
<211>  1857
<212>  DNA
<213>  Homo Sapiens

<400>  5049
ggatgtctga ctcaactcta tgaaaacgcc ttcttcagag gtggggatgt agcttccatg       60

tacaccccaa atgcccaata ctgccagatg aggtgcacat tccacccaag gtgtttgcta      120

ttcagttttc ttccagcaag ttcaatcaat gacatggaga aaaggtttgg ttgcttcttg      180

aaagatagtg ttacaggaac cctgccaaaa gtacatcgaa caggtgcagt ttctggacat      240

tccttgaagc aatgtggtca tcaaataagt gcttgccatc gagacattta taaaggagtt      300

gatatgagag gagtcaattt taatgtgtct aaggttagca gtgttgaaga atgccaaaaa      360

aggtgcacca ataacattcg ctgccagttt ttttcatatg ccacgcaaac atttcacaag      420

gcagagtacc ggaacaattg cctattaaag tacagtcccg gaggaacacc taccgctata      480

aaggtgctga gtaacgtgga atctggattc tcactgaagc cctgtgccct ttcagaaatt      540

ggttgccaca tgaacatctt ccagcatctt gcgttctcag atgtggatgt tgccagggtt      600

ctcactccag atgcttttgt gtgtcggacc atctgcacct atcaccccaa ctgcctcttc      660

tttacattct atacaaatgt atggaaaatc gagtcacaaa gaaatgtttg tcttcttaaa      720

acatctgaaa gtggcacacc aagttcctct actcctcaag aaaacaccat atctggatat      780

agccttttaa cctgcaaaag aactttacct gaaccctgcc attctaaaat ttacccggga      840

gttgactttg gaggagaaga attgaatgtg acttttgtta aaggagtgaa tgtttgccaa      900

gagacttgca caaagatgat tcgctgtcag tttttcactt attctttact cccagaagac      960

tgtaaggaag agaagtgtaa gtgtttctta agattatcta tggatggttc tccaactagg     1020

attgcgtatg ggacacaagg gagctctggt tactctttga gattgtgtaa cactggggac     1080

aactctgtct gcacaacaaa aacaagcaca cgcattgttg gaggaacaaa ctcttcttgg     1140

ggagagtggc cctggcaggt gagcctgcag gtgaagctga cagctcagag gcacctgtgt     1200

ggagggtcac tcataggaca ccagtgggtc ctcactgctg cccactgctt tgatgggctt     1260

cccctgcagg atgtttggcg catctatagt ggcattttaa atctgtcaga cattacaaaa     1320

gatacacctt tctcacaaat aaaagagatt attattcacc aaaactataa agtctcagaa     1380

gggaatcatg atatcgcctt gataaaactc caggctcctt tgaattacac tgaattccaa     1440

aaaccaatat gcctaccttc caaaggtgac acaagcacaa tttataccaa ctgttgggta     1500

accggatggg gcttctcgaa ggagaaaggt gaaatccaaa atattctaca aaaggtaaat     1560

attcctttgg taacaaatga agaatgccag aaaagatatc aagattataa aataacccaa     1620

cggatggtct gtgctggcta taaagaaggg ggaaaagatg cttgtaaggg agattcaggt     1680

ggtcccttag tttgcaaaca caatggaatg tggcgtttgg tgggcatcac cagctggggt     1740

gaaggctgtg cccgcaggga gcaacctggt gtctacacca aagtcgctga gtacatggac     1800

tggattttag agaaaacaca gagcagtgat ggaaaagctc agatgcagtc accagca        1857


<210>  5050
<211>  510
<212>  DNA
<213>  Homo Sapiens

<400>  5050
tttgtcctca ctgaggggaa ccctcgctgg gagcaaacac atctgaccta caggattgaa       60

aattacacgc cagatttgcc aagagcagat gtggaccatg ccattgagaa agccttccaa      120

ctctggagta atgtcacacc tctgacattc accaaggtct ctgagggtca agcagacatc      180

atgatatctt ttgtcagggg agatcatcgg gacaactctc cttttgatgg acctggagga      240

aatcttgctc atgcttttca accaggccca ggtattggag gggatgctca ttttgatgaa      300

gatgaaaggt ggaccaacaa tttcagagag tacaacttac atcgtgttgc ggctcatgaa      360

ctcggccatt ctcttggact ctcccattct actgatatcg gggctttgat gtaccctagc      420

tacaccttca gtggtgatgt tcagctagct caggatgaca ttgatggcat ccaagccata      480

tatggacgtt cccaaaatcc tgtccagccc                                       510


<210>  5051
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  5051
tctggaaagt ccttcaaagc tggagtctgt cctcctaaga aatctgccca gtgccttaga       60

tacaagaaac ctgagtgcca gagtgactgg cagtgtccag ggaagaagag atgttgtcct      120

gacacttgtg gcatcaaatg cctggatcct gttgacaccc caaacccaac aaggaggaag      180

cctgggaagt gcccagtgac ttatggccaa tgtttgatgc ttaacccccc caatttctgt      240

gagatggatg gccagtgcaa gcgtgacttg aagtgttgca tgggcatgtg tgggaaatcc      300

tgcgtttccc ctgtgaaagc t                                                321


<210>  5052
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  5052
atggcccagc agtggagcct ccaaaggctc gcaggccgcc atccgcagga cagctatgag       60

gacagcaccc agtccagcat cttcacctac accaacagca actccaccag aggccccttc      120

gaaggcccga attaccacat cgctcccaga tgggtg                                156


<210>  5053
<211>  1647
<212>  DNA
<213>  Homo Sapiens

<400>  5053
aattgtggtc ctccacccac tttatcattt gctgccccga tggatattac gttgactgag       60

acacgcttca aaactggaac tactctgaaa tacacctgcc tccctggcta cgtcagatcc      120

cattcaactc agacgcttac ctgtaattct gatggcgaat gggtgtataa caccttctgt      180

atctacaaac gatgcagaca cccaggagag ttacgtaatg ggcaagtaga gattaagaca      240

gatttatctt ttggatcaca aatagaattc agctgttcag aaggattttt cttaattggc      300

tcaaccacta gtcgttgtga agtccaagat agaggagttg gctggagtca tcctctccca      360

caatgtgaaa ttgtcaagtg taagcctcct ccagacatca ggaatggaag gcacagcggt      420

gaagaaaatt tctacgcata cggcttttct gtcacctaca gctgtgaccc ccgcttctca      480

ctcttgggcc atgcctccat ttcttgcact gtggagaatg aaacaatagg tgtttggaga      540

ccaagccctc ctacctgtga aaaaatcacc tgtcgcaagc cagatgtttc acatggggaa      600

atggtctctg gatttggacc catctataat tacaaagaca ctattgtgtt taagtgccaa      660

aaaggttttg ttctcagagg cagcagtgta attcattgtg atgctgatag caaatggaat      720

ccttctcctc ctgcttgtga gcccaatagt tgtattaatt taccagacat tccacatgct      780

tcctgggaaa catatcctag gccgacaaaa gaggatgtgt atgttgttgg gactgtgtta      840

aggtaccgct gtcatcctgg ctacaaaccc actacagatg agcctacgac tgtgatttgt      900

cagaaaaatt tgagatggac cccataccaa ggatgtgagg cgttatgttg ccctgaacca      960

aagctaaata atggtgaaat cactcaacac aggaaaagtc gtcctgccaa tcactgtgtt     1020

tatttctatg gagatgagat ttcattttca tgtcatgaga ccagtaggtt ttcagctata     1080

tgccaaggag atggcacgtg gagtccccga acaccatcat gtggagacat ttgcaatttt     1140

cctcctaaaa ttgcccatgg gcattataaa caatctagtt catacagctt tttcaaagaa     1200

gagattatat atgaatgtga taaaggctac attctggtcg gacaggcgaa actctcctgc     1260

agttattcac actggtcagc tccagcccct caatgtaaag ctctgtgtcg gaaaccagaa     1320

ttagtgaatg gaaggttgtc tgtggataag gatcagtatg ttgagcctga aaatgtcacc     1380

atccaatgtg attctggcta tggtgtggtt ggtccccaaa gtatcacttg ctctgggaac     1440

agaacctggt acccagaggt gcccaagtgt gagtgggaga cccccgaagg ctgtgaacaa     1500

gtgctcacag gcaaaagact catgcagtgt ctcccaaacc cagaggatgt gaaaatggcc     1560

ctggaggtat ataagctgtc tctggaaatt gaacaactgg aactacagag agacagcgca     1620

agacaatcca ctttggataa agaacta                                         1647


<210>  5054
<211>  1377
<212>  DNA
<213>  Homo Sapiens

<400>  5054
gaccaagagt catgcaaggg ccgctgcact gagggcttca acgtggacaa gaagtgccag       60

tgtgacgagc tctgctctta ctaccagagc tgctgcacag actatacggc tgagtgcaag      120

ccccaagtga ctcgcgggga tgtgttcact atgccggagg atgagtacac ggtctatgac      180

gatggcgagg agaaaaacaa tgccactgtc catgaacagg tggggggccc ctccctgacc      240

tctgacctcc aggcccagtc caaagggaat cctgagcaga cacctgttct gaaacctgag      300

gaagaggccc ctgcgcctga ggtgggcgcc tctaagcctg aggggataga ctcaaggcct      360

gagacccttc atccagggag acctcagccc ccagcagagg aggagctgtg cagtgggaag      420

cccttcgacg ccttcaccga cctcaagaac ggttccctct ttgccttccg agggcagtac      480

tgctatgaac tggacgaaaa ggcagtgagg cctgggtacc ccaagctcat ccgagatgtc      540

tggggcatcg agggccccat cgatgccgcc ttcacccgca tcaactgtca ggggaagacc      600

tacctcttca agggtagtca gtactggcgc tttgaggatg gtgtcctgga ccctgattac      660

ccccgaaata tctctgacgg cttcgatggc atcccggaca acgtggatgc agccttggcc      720

ctccctgccc atagctacag tggccgggag cgggtctact tcttcaaggg gaaacagtac      780

tgggagtacc agttccagca ccagcccagt caggaggagt gtgaaggcag ctccctgtcg      840

gctgtgtttg aacactttgc catgatgcag cgggacagct gggaggacat cttcgagctt      900

ctcttctggg gcagaacctc tgctggtacc agacagcccc agttcattag ccgggactgg      960

cacggtgtgc cagggcaagt ggacgcagcc atggctggcc gcatctacat ctcaggcatg     1020

gcaccccgcc cctccttggc caagaaacaa aggtttaggc atcgcaaccg caaaggctac     1080

cgttcacaac gaggccacag ccgtggccgc aaccagaact cccgccggcc atcccgcgcc     1140

atgtggctgt ccttgttctc cagtgaggag agcaacttgg gagccaacaa ctatgatgac     1200

tacaggatgg actggcttgt gcctgccacc tgtgaaccca tccagagtgt cttcttcttc     1260

tctggagaca agtactaccg agtcaatctt cgcacacggc gagtggacac tgtggaccct     1320

ccctacccac gctccatcgc tcagtactgg ctgggctgcc cagctcctgg ccatctg        1377


<210>  5055
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  5055
gccgtgtggc agttccgcaa aatgatcaag tgcgtgatcc cggggagtga ccccttcttg       60

gaatacaaca actacggctg ctactgtggc ttggggggct caggcacccc cgtggatgaa      120

ctggacaagt gctgccagac acatgacaac tgctatgacc aggccaagaa gctggacagc      180

tgtaaatttc tgctggacaa cccgtacacc cacacctatt catactcgtg ctctggctcg      240

gcaatcacct gtagcagcaa aaacaaagag tgtgaggcct tcatttgcaa ctgcgaccgc      300

aacgctgcca tctgcttttc aaaagctcca tataacaagg cacacaagaa cctggacacc      360

aagaagtatt gtcagagt                                                    378


<210>  5056
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  5056
gcccgcccct gcatccctaa aagcttcggc tacagctcgg tggtgtgtgt ctgcaatgcc       60

acatactgtg actcctttga ccccccgacc tttcctgccc ttggtacctt cagccgctat      120

gagagtacac gcagtgggcg acggatggag ctgagtatgg ggcccatcca ggctaatcac      180

acgggcacag gcctgctact gaccctgcag ccagaacaga agttccagaa agtgaaggga      240

tttggagggg ccatgacaga tgctgctgct ctcaacatcc ttgccctgtc accccctgcc      300

caaaatttgc tacttaaatc gtacttctct gaagaaggaa tcggatataa catcatccgg      360

gtacccatgg ccagctgtga cttctccatc cgcacctaca cctatgcaga cacccctgat      420

gatttccagt tgcacaactt cagcctccca gaggaagata ccaagctcaa gatacccctg      480

attcaccgag ccctgcagtt ggcccagcgt cccgtttcac tccttgccag cccctggaca      540

tcacccactt ggctcaagac caatggagcg gtgaatggga aggggtcact caagggacag      600

cccggagaca tctaccacca gacctgggcc agatactttg tgaagttcct ggatgcctat      660

gctgagcaca agttacagtt ctgggcagtg acagctgaaa atgagccttc tgctgggctg      720

ttgagtggat accccttcca gtgcctgggc ttcacccctg aacatcagcg agacttcatt      780

gcccgtgacc taggtcctac cctcgccaac agtactcacc acaatgtccg cctactcatg      840

ctggatgacc aacgcttgct gctgccccac tgggcaaagg tggtactgac agacccagaa      900

gcagctaaat atgttcatgg cattgctgta cattggtacc tggactttct ggctccagcc      960

aaagccaccc taggggagac acaccgcctg ttccccaaca ccatgctctt tgcctcagag     1020

gcctgtgtgg gctccaagtt ctgggagcag agtgtgcggc taggctcctg ggatcgaggg     1080

atgcagtaca gccacagcat catcacgaac ctcctgtacc atgtggtcgg ctggaccgac     1140

tggaaccttg ccctgaaccc cgaaggagga cccaattggg tgcgtaactt tgtcgacagt     1200

cccatcattg tagacatcac caaggacacg ttttacaaac agcccatgtt ctaccacctt     1260

ggccacttca gcaagttcat tcctgagggc tcccagagag tggggctggt tgccagtcag     1320

aagaacgacc tggacgcagt ggcactgatg catcccgatg gctctgctgt tgtggtcgtg     1380

ctaaaccgct cctctaagga tgtgcctctt accatcaagg atcctgctgt gggcttcctg     1440

gagacaatct cacctggcta ctccattcac acctacctgt ggcgtcgcca g              1491


<210>  5057
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  5057
cagcctccgc gccgctacac cccagactgg ccgagcctgg attctcggcc gctgccggcc       60

tggttcgacg aagccaagtt cggggtgttc atccactggg gcgtgttctc ggtgcccgcc      120

tggggcagcg agtggttctg gtggcactgg cagggcgagg ggcggccgca gtaccagcgc      180

ttcatgcgcg acaactaccc gcccggcttc agctacgccg acttcggacc gcagttcact      240

gcgcgcttct tccacccgga ggagtgggcc gacctcttcc aggccgcggg cgccaagtat      300

gtagttttga cgacaaagca tcacgaaggc ttcacaaact ggccgagtcc tgtgtcttgg      360

aactggaact ccaaagacgt ggggcctcat cgggatttgg ttggtgaatt gggaacagct      420

ctccggaaga ggaacatccg ctatggacta taccactcac tcttagagtg gttccatcca      480

ctctatctac ttgataagaa aaatggcttc aaaacacagc attttgtcag tgcaaaaaca      540

atgccagagc tgtacgacct tgttaacagc tataaacctg atctgatctg gtctgatggg      600

gagtgggaat gtcctgatac ttactggaac tccacaaatt ttctttcatg gctctacaat      660

gacagccctg tcaaggatga ggtggtagta aatgaccgat ggggtcagaa ctgttcctgt      720

caccatggag gatactataa ctgtgaagat aaattcaagc cacagagctt gccagatcac      780

aagtgggaga tgtgcaccag cattgacaag ttttcctggg gctatcgtcg tgacatggca      840

ttgtctgatg ttacagaaga atctgaaatc atttcggaac tggttcagac agtaagtttg      900

ggaggcaact atcttctgaa cattggacca actaaagatg gactgattgt tcccatcttc      960

caagaaaggc ttcttgctgt tgggaaatgg ctgagcatca atggggaggc tatctatgcc     1020

tccaaaccat ggcgggtgca atgggaaaag aacacaacat ctgtatggta tacctcaaag     1080

ggatcggctg tttatgccat ttttctgcac tggccagaaa atggagtctt aaaccttgaa     1140

tcccccataa ctacctcaac tacaaagata acaatgctgg gaattcaagg agatctgaag     1200

tggtccacag atccagataa aggtctcttc atctctctac cccagttgcc accctctgct     1260

gtccccgcag agtttgcttg gactataaag ctgacaggag tgaag                     1305


<210>  5058
<211>  1035
<212>  DNA
<213>  Homo Sapiens

<400>  5058
gcaatggtat cagaattcct caagcaggcc tggtttattg aaaatgaaga gcaggaatat       60

gttcaaactg tgaagtcatc caaaggtggt cccggatcag cggtgagccc ctatcctacc      120

ttcaatccat cctcggatgt cgctgccttg cataaggcca taatggttaa aggtgtggat      180

gaagcaacca tcattgacat tctaactaag cgaaacaatg cacagcgtca acagatcaaa      240

gcagcatatc tccaggaaac aggaaagccc ctggatgaaa cactgaagaa agcccttaca      300

ggtcaccttg aggaggttgt tttagctctg ctaaaaactc cagcgcaatt tgatgctgat      360

gaacttcgtg ctgccatgaa gggccttgga actgatgaag atactctaat tgagattttg      420

gcatcaagaa ctaacaaaga aatcagagac attaacaggg tctacagaga ggaactgaag      480

agagatctgg ccaaagacat aacctcagac acatctggag attttcggaa cgctttgctt      540

tctcttgcta agggtgaccg atctgaggac tttggtgtga atgaagactt ggctgattca      600

gatgccaggg ccttgtatga agcaggagaa aggagaaagg ggacagacgt aaacgtgttc      660

aataccatcc ttaccaccag aagctatcca caacttcgca gagtgtttca gaaatacacc      720

aagtacagta agcatgacat gaacaaagtt ctggacctgg agttgaaagg tgacattgag      780

aaatgcctca cagctatcgt gaagtgcgcc acaagcaaac cagctttctt tgcagagaag      840

cttcatcaag ccatgaaagg tgttggaact cgccataagg cattgatcag gattatggtt      900

tcccgttctg aaattgacat gaatgatatc aaagcattct atcagaagat gtatggtatc      960

tccctttgcc aagccatcct ggatgaaacc aaaggagatt atgagaaaat cctggtggct     1020

ctttgtggag gaaac                                                      1035


<210>  5059
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  5059
gactcatgga tggaggaagt tattaaatta tgcggccgcg aattagttcg cgcgcagatt       60

gccatttgcg gcatgagcac ctggagcaaa aggtctctga gccaggaaga tgctcctcag      120

acacctagac cagtggcaga aattgtgcca tccttcatca acaaagatac agaaaccata      180

aatatgatgt cagaatttgt tgctaatttg ccacaggagc tgaagttaac cctgtctgag      240

atgcagccag cattaccaca gctacaacaa catgtacctg tattaaaaga ttccagtctt      300

ctctttgaag aatttaagaa acttattcgc aatagacaaa gtgaagccgc agacagcagt      360

ccttcagaat taaaatactt aggcttggat actcattctc gaaaaaagag acaactctac      420

agtgcattgg ctaataaatg ttgccatgtt ggttgtacca aaagatctct tgctagattt      480

tgc                                                                    483


<210>  5060
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  5060
gggatcatta tcaacctgga gaacggtgag ctctgcatga atagtgccca gtgtaagagc       60

aattgctgcc agcattcaag tgcgctgggc ctggcccgct gcacatccat ggccagcgag      120

aacagcgagt gctctgtcaa gacgctctat gggatttact acaagtgtcc ctgtgagcgt      180

ggcctgacct gtgagggaga caagaccatc gtgggctcca tcaccaacac caactttggc      240

atctgccatg acgctggacg ctccaagcag                                       270


<210>  5061
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  5061
gaggcccaga cagagacgtg tacagtggcc ccccgtgaaa gacagaattg tggttttcct       60

ggtgtcacgc cctcccagtg tgcaaataag ggctgctgtt tcgacgacac cgttcgtggg      120

gtcccctggt gcttctatcc taataccatc gacgtccctc cagaagagga gtgtgaattt      180


<210>  5062
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  5062
aagaagcgcc cgaagcctgg aggatggaac actgggggca gccgataccc ggggcagggc       60

agccctggag gcaaccgcta cccacctcag ggcggtggtg gctgggggca gcctcatggt      120

ggtggctggg ggcagcctca tggtggtggc tgggggcagc cccatggtgg tggctgggga      180

cagcctcatg gtggtggctg gggtcaagga ggtggcaccc acagtcagtg gaacaagccg      240

agtaagccaa aaaccaacat gaagcacatg gctggtgctg cagcggctgg ggcagtggtg      300

gggggccttg gcggctactt gctgggaagt gccatgagca ggcccatcat acatttcggc      360

agtgactatg aggaccgtta ctatcgtgaa aacatgcacc gttaccccaa ccaagtgtac      420

tacaggccca tggatgagta cagcaaccag aacaactttg tgcacgactg cgtcaatatc      480

acaatcaagc agcacacggt caccacaacc accaaggggg agaacttcac cgagaccgac      540

gttaagatga tggagcgcgt ggttgagcag atgtgtatca cccagtacga gagggaatct      600

caggcctatt accagagagg atcg                                             624


<210>  5063
<211>  1521
<212>  DNA
<213>  Homo Sapiens

<400>  5063
gtgagtccca ctgactgcag tgctgttgag ccggaggctg agaaagctct agacctgatc       60

aataaaaggc gacgggatgg ctaccttttc caattgctgc ggattgctga tgcccacttg      120

gacagagtgg aaaatacaac tgtatattac ttagtcttag atgtgcaaga atcggactgt      180

tcggtcctat ccaggaaata ctggaatgac tgtgagccac ctgattccag acgtccatct      240

gaaatagtga tcggacaatg taaggtaata gctacaagac attcccatga atctcaggac      300

ctcagagtga ttgactttaa ctgcaccaca agttctgtct cttcagcact ggccaatacc      360

aaagatagtc cggtcctcat agatttcttt gaggatactg agcgctacag aaaacaagcc      420

aacaaagccc ttgagaagta caaagaggag aatgatgact ttgcctcttt cagagtggac      480

cgaatcgaga gagttgcaag agtgagagga ggggaaggaa ctggttactt cgtggacttc      540

tctgtgcgga actgccccag acaccatttc cccagacacc ccaatgtctt tggattctgc      600

agagcagatt tgttctatga tgtagaagcc ttggacttgg aaagcccgaa aaaccttgtc      660

ataaactgtg aagtcttcga ccctcaggaa catgagaaca tcaatggtgt accgcctcat      720

ttgggacatc ccttccactg gggtgggcat gagcgttctt ctaccaccaa gcctccattc      780

aagccccatg gatctagaga tcatcatcat ccccacaagc cacacgaaca tggaccccca      840

cctcctccag atgaaagaga tcactcacat ggacccccac ttccacaagg ccctcctcca      900

ctattgccca tgtcctgctc aagttgtcaa catgccactt ttggcacaaa tggggcccaa      960

agacattctc ataataataa ttccagtgac ctccatcccc ataagcatca ttcccatgaa     1020

cagcatcccc acggacacca tccccatgca caccatcctc atgaacatga tacccataga     1080

cagcatcccc atggacacca cccccatgga caccatcctc atggacacca cccccatgga     1140

caccatcccc atggacacca tccccactgc catgatttcc aagactatgg accttgtgac     1200

ccaccacccc ataaccaagg tcactgttgc catggccacg gcccaccacc tgggcactta     1260

agaaggcgag gcccaggtaa aggaccccgt cccttccatt gcagacaaat tggatctgtg     1320

taccgactcc ctcctctaag aaaaggtgag gtgctgccac ttcctgaggc caattttccc     1380

agcttcccat tgccgcacca caaacatcct ctaaagccag acaatcagcc ctttcctcaa     1440

tcagtctctg aatcatgtcc agggaagttc aagagtgggt ttccacaagt ttccatgttt     1500

tttacacata catttccaaa a                                               1521


<210>  5064
<211>  1119
<212>  DNA
<213>  Homo Sapiens

<400>  5064
ctgagacctg ttctccccac ccagagtgcc cacgaccctc cggctgtcca cctcagcaat       60

ggcccaggac aagagcctat cgctgtcatg acctttgacc tcaccaagat cacaaaaacc      120

tcctcctcct ttgaggttcg aacctgggac ccagagggag tgatttttta tggggatacc      180

aaccctaagg atgactggtt tatgctggga cttcgagacg gcaggcctga gatccaactg      240

cacaatcact gggcccagct tacggtgggt gctggaccac ggctggatga tgggagatgg      300

caccaggtgg aagtcaagat ggagggggac tctgtgctgc tggaggtgga tggggaggag      360

gtgctgcgcc tgagacaggt ctctgggccc ctgaccagca aacgccatcc catcatgagg      420

attgcgcttg gggggctgct cttccccgct tccaaccttc ggttgccgct ggttcctgcc      480

ctggatggct gcctgcgccg ggattcctgg ctggacaaac aggccgagat ctcagcatct      540

gcccccacta gcctcagaag ctgtgatgta gaatcaaatc ccgggatatt tctccctcca      600

gggactcagg cagaattcaa tctccgagac attccccagc ctcatgcaga gccctgggcc      660

ttctctttgg acctgggact caagcaggca gcaggctcag gccacctcct tgctcttggg      720

acaccagaga acccatcttg gctcagtctc cacctccaag atcaaaaggt ggtgttgtct      780

tctgggtcgg ggccagggct ggatctgccc ctggtcttgg gactccctct tcagctgaag      840

ctgagtatgt ccagggtggt cttgagccaa gggtcgaaga tgaaggccct tgccctgcct      900

cccttaggcc tggctcccct ccttaacctc tgggccaagc ctcaagggcg tctcttcctg      960

ggggctttac caggagaaga ctcttccacc tctttttgcc tgaatggcct ttgggcacaa     1020

ggtcagaggc tggatgtgga ccaggccctg aacagaagcc atgagatctg gactcacagc     1080

tgcccccaga gcccaggcaa tggcactgac gcttcccat                            1119


<210>  5065
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  5065
gccaacagca gtggccgatg gtggggtatt gtgaacgtag cctcctccac gaacctgctt       60

acagactcca agagtctgca actggtactc gagcccagtc tgcagctgtt gagccgcaaa      120

cagcggcgtc tgatacgcca aaatccgggg atcctgcaca gcgtgagtgg ggggctgcag      180

agtgccgtgc gcgagtgcaa gtggcagttc cggaatcgcc gctggaactg tcccactgct      240

ccagggcccc acctcttcgg caagatcgtc aaccgaggct gtcgagaaac ggcgtttatc      300

ttcgctatca cctccgccgg ggtcacccat tcggtggcgc gctcctgctc agaaggttcc      360

atcgaatcct gcacgtgtga ctaccggcgg cgcggccccg ggggccccga ctggcactgg      420

gggggctgca gcgacaacat tgacttcggc cgcctcttcg gccgggagtt cgtggactcc      480

ggggagaagg ggcgggacct gcgcttcctc atgaaccttc acaacaacga ggcaggccgt      540

acgaccgtat tctccgagat gcgccaggag tgcaagtgcc acgggatgtc cggctcatgc      600

acggtgcgca cgtgctggat gcggctgccc acgctgcgcg ccgtgggcga tgtgctgcgc      660

gaccgcttcg acggcgcctc gcgcgtcctg tacggcaacc gcggcagcaa ccgcgcttcg      720

cgggcggagc tgctgcgcct ggagccggaa gacccggccc acaaaccgcc ctccccccac      780

gacctcgtct acttcgagaa atcgcccaac ttctgcacgt acagcggacg cctgggcaca      840

gcaggcacgg cagggcgcgc ctgtaacagc tcgtcgcccg cgctggacgg ctgcgagctg      900

ctctgctgcg gcaggggcca ccgcacgcgc acgcagcgcg tcaccgagcg ctgcaactgc      960

accttccact ggtgctgcca cgtcagctgc cgcaactgca cgcacacgcg cgtactgcac     1020

gagtgtctg                                                             1029


<210>  5066
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  5066
cagtattcct caaatacaca acaaggacga acatctattg ttcatctgtt tgaatggcga       60

tgggttgata ttgctcttga atgtgagcga tatttagctc ccaagggatt tggaggggtt      120

caggtctctc caccaaatga aaatgttgcc attcacaacc ctttcagacc ttggtgggaa      180

agataccaac cagttagcta taaattatgc acaagatctg gaaatgaaga tgaatttaga      240

aacatggtga ctagatgcaa caatgttggg gttcgtattt atgtggatgc tgtaattaat      300

catatgtgtg gtaatgctgt gagtgcagga acaagcagta cctgtggaag ttacttcaac      360

cctggaagta gggactttcc agcagtccca tattctggat gggattttaa tgatggtaaa      420

tgtaaaactg gaagtggaga tatcgagaac tataatgatg ctactcaggt cagagattgt      480

cgtctgtctg gtcttctcga tcttgcactg gggaaggatt atgtgcgttc taagattgcc      540

gaatatatga accatctcat tgacattggt gttgcagggt tcagaattga tgcttccaag      600

cacatgtggc ctggagacat aaaggcaatt ttggacaaac tgcataatct aaacagtaac      660

tggttcccgg aaggtagtaa acctttcatt taccaggagg taattgatct gggtggtgag      720

ccaattaaaa gcagtgacta ctttggtaat ggccgggtga cagaattcaa gtatggtgca      780

aaactcggca cagttattcg caagtggaat ggagagaaga tgtcttactt aaagaactgg      840

ggagaaggtt ggggtttcat gccttctgac agagcgcttg tctttgtgga taaccatgac      900

aatcaacgag gacatggcgc tggaggagcc tctatactta ccttctggga tgctaggctg      960

tacaaaatgg cagttggatt tatgcttgct catccttatg gatttacacg agtaatgtca     1020

agctaccgtt ggccaagata ttttgaaaat ggaaaagatg ttaatgattg ggttgggcca     1080

ccaaatgata atggagtaac taaagaagtt actattaatc cagacactac ttgtggcaat     1140

gactgggtct gtgaacatcg atggcgccaa ataaggaaca tggttaattt ccgcaatgta     1200

gtggatggcc agccttttac aaactggtat gataatggga gcaaccaagt ggcttttggg     1260

agaggaaaca gaggattcat tgttttcaac aatgatgact ggacattttc tttaactttg     1320

caaactggtc ttcctgctgg cacatactgt gatgtcattt ctggagataa aattaatggc     1380

aactgcacag gcattaaaat ctacgtttct gatgatggca aagctcattt ttctattagt     1440

aactctgctg aagatccatt tattgcaatt catgctgaat ctaaattg                  1488


<210>  5067
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  5067
gtcgcggcca aatggaagga cgatgttatt aaattatgcg gccgcgaatt agttcgcgcg       60

cagattgcca tttgcggcat gagcacctgg agcaaaaggt ctctgagcca ggaagatgct      120

cctcagacac ctagaccagt ggcagaaatt gtaccatcct tcatcaacaa agatacagaa      180

actataatta tcatgttgga attcattgct aatttgccac cggagctgaa ggcagcccta      240

tctgagaggc aaccatcatt accagagcta cagcagtatg tacctgcatt aaaggattcc      300

aatcttagct ttgaagaatt taagaaactt attcgcaata ggcaaagtga agccgcagac      360

agcaatcctt cagaattaaa atacttaggc ttggatactc attctcaaaa aaagagacga      420

ccctacgtgg cactgtttga gaaatgttgc ctaattggtt gtaccaaaag gtctcttgct      480

aaatattgc                                                              489


<210>  5068
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5068
caggagcacc ccctgcatgg ctgctcagcc tccaacagct cagaggtgga cggcggtgag       60

aacatgacat gggccggggc aagacccacg ctggggccgg gcaacaggag cttggctggg      120

cagtctgggc aggggaagcc ccggggccag cccaacacg                             159


<210>  5069
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5069
atgtggtcga cgagaagccc caacagcacg gcgtggcctc tcagcctcga gcctgatcca       60

gggatggcct ctgcctccac cacaatgcat actaccacca ttgcagagcc tgatccaggg      120

atgtctggat ggccggatgg cagaatggag acctccaccc ccaccataat g               171


<210>  5070
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  5070
tttacttact ttgtgattct ggctgagaac ggcttcctcc caattcacct gttgggcctc       60

cgagtggact gggatgaccg ctggatcaac gatgtggaag acagctacgg gcagcagtgg      120

acctatgagc agaggaaaat cgtggagttc acctgc                                156


<210>  5071
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  5071
gaatttaagc ccacatatca ggaccgagtg gccccgccag gattaacaca gattcctcag       60

atccagaaga ctgaaatttc ctttcgtcct aatgatccca agagctatga ggcatatgta      120

ctgaacatag ttaggttcct ggaaaagtac aaagattcag cccagaggga tgacatgatt      180

tttgaagatt gtggcgatgt gcccagtgaa ccgaaagaac gaggagactt taatcatgaa      240

cgaggagagc gaaaggtctg cagattcaag cttgaatggc tgggaaattg ctctggatta      300

aatgatgaaa cttatggcta caaagagggc aaaccgtgca ttattataaa gctcaaccga      360

gttctaggct tcaaacctaa gcctcccaag aatgagtcct tggagactta cccagtgatg      420

aagtataacc caaatgtcct tcccgttcag tgcactggca agcgagatga agataaggat      480

aaagttggaa atgtggagta ttttggactg ggcaactccc ctggttttcc tctgcagtat      540

tatccgtact atggcaaact cctgcagccc aaatacctgc agcccctgct ggccgtacag      600

ttcaccaatc ttaccatgga cactgaaatt cgcatagagt gtaaggcgta cggtgagaac      660

attgggtaca gtgagaaaga ccgttttcag ggacgttttg atgtaaaaat tgaagttaag      720

agc                                                                    723


<210>  5072
<211>  1971
<212>  DNA
<213>  Homo Sapiens

<400>  5072
atgccagtgg ataacaggaa ccacaatgaa ggaatggtga ctcgctgcat cattgaggtc       60

ctctcaaatg ccttgtcgaa gtccagcgct ccacccatca cccctgagtg ccgccaagtc      120

ctgaagacga gtagaaaaga cgtcaaagac aaagagacaa ctgaaaatga aaacacaaag      180

tttgaagtaa gattgttaag agacccagct gatgcctcgg aagcccacga gtcctccagc      240

aggggagagg caggagcccc aggggaggag gacatccaag gcccaacaaa ggcagacaca      300

gagaaatggg cagagggagg cgggcacagc cgagagcgag cggatgagcc ccagtggagc      360

ctctatccct ccgacagcca agtctctgaa gaagtgaaga cacgccattc tgagaagagc      420

cagagagagg atgaggagga ggaggaggga gagaactatc aaaaagggga gcgaggggaa      480

gatagcagtg aagagaaaca ccttgaagag ccaggagaga cacaaaacgc ttttctcaat      540

gaaagaaagc aggcttcagc tataaaaaaa gaggagttag tggccagatc ggaaacacat      600

gctgccgggc attctcagga gaagacacat agccgagaga agagtagcca ggagagtgga      660

gaggaggcag ggagccagga gaatcacccc caggagtcta aaggccaacc ccgaagccag      720

gaagaatctg aggaaggtga ggaagatgcc acctctgagg tggacaaacg acgcacgagg      780

cccagacacc accacgggag gagcaggccc gacaggtcct ctcaaggagg gagtcttccc      840

tctgaggaaa agggacaccc ccaggaggaa tctgaggagt caaacgtcag catggccagt      900

ttaggggaaa agagggacca ccattcaacc cactacaggg cttcagagga agaacctgaa      960

tatggagaag aaataaaggg ttatccaggc gtccaggccc ctgaggacct ggagtgggag     1020

cgctataggg gcagaggaag tgaagaatac agggctccaa gacctcagag tgaggagagt     1080

tgggatgagg aggacaagag aaactacccc agcttagagc ttgataagat ggcacatgga     1140

tatggtgaag aaagtgagga agagaggggc cttgagccgg gaaagggacg ccatcacaga     1200

ggcaggggag gggagccacg tgcctatttc atgtctgaca ccagagaaga gaaaaggttc     1260

ttgggtgaag gacaccaccg tgtccaagaa aaccagatgg acaaggcaag gaggcatcca     1320

caaggtgcgt ggaaagagct ggacagaaat tatctcaact acggtgagga aggagcccca     1380

gggaagtggc agcagcaggg agacctgcag gacactaaag aaaacaggga ggaagctagg     1440

tttcaagata aacaatatag ctcccatcac acagctgaaa agaggaagag attaggggaa     1500

ctgttcaacc catactacga ccctctccag tggaagagca gccattttga aagaagagac     1560

aacatgaatg acaattttct cgagggtgag gaggaaaatg agctgacctt gaacgagaag     1620

aatttcttcc cagaatacaa ctatgactgg tgggagaaaa agcccttctc tgaggatgtg     1680

aactgggggt atgagaagag aaacctcgcc agggtcccca agctggacct gaaaaggcaa     1740

tatgacaggg tggcccaact ggaccagctc cttcactaca ggaagaagtc agctgagttt     1800

ccagacttct atgattctga ggagccggtg agcacccacc aggaggcaga aaatgaaaag     1860

gacagggctg accagacagt cctgacagag gacgagaaaa aagaactcga aaacttggct     1920

gcaatggatt tggaactaca gaagatagct gagaaattca gccaaagggg c              1971


<210>  5073
<211>  1989
<212>  DNA
<213>  Homo Sapiens

<400>  5073
ctggaggtac ccactgatgg taatgctggc ctgctggctg aaccccagat tgccatgttc       60

tgtggcagac tgaacatgca catgaatgtc cagaatggga agtgggattc agatccatca      120

gggaccaaaa cctgcattga taccaaggaa ggcatcctgc agtattgcca agaagtctac      180

cctgaactgc agatcaccaa tgtggtagaa gccaaccaac cagtgaccat ccagaactgg      240

tgcaagcggg gccgcaagca gtgcaagacc catccccact ttgtgattcc ctaccgctgc      300

ttagttggtg agtttgtaag tgatgccctt ctcgttcctg acaagtgcaa attcttacac      360

caggagagga tggatgtttg cgaaactcat cttcactggc acaccgtcgc caaagagaca      420

tgcagtgaga agagtaccaa cttgcatgac tacggcatgt tgctgccctg cggaattgac      480

aagttccgag gggtagagtt tgtgtgttgc ccactggctg aagaaagtga caatgtggat      540

tctgctgatg cggaggagga tgactcggat gtctggtggg gcggagcaga cacagactat      600

gcagatggga gtgaagacaa agtagtagaa gtagcagagg aggaagaagt ggctgaggtg      660

gaagaagaag aagccgatga tgacgaggac gatgaggatg gtgatgaggt agaggaagag      720

gctgaggaac cctacgaaga agccacagag agaaccacca gcattgccac caccaccacc      780

accaccacag agtctgtgga agaggtggtt cgagaggtgt gctctgaaca agccgagacg      840

gggccgtgcc gagcaatgat ctcccgctgg tactttgatg tgactgaagg gaagtgtgcc      900

ccattctttt acggcggatg tggcggcaac cggaacaact ttgacacaga agagtactgc      960

atggccgtgt gtggcagcgc cattcctaca acagcagcca gtacccctga tgccgttgac     1020

aagtatctcg agacacctgg ggatgagaat gaacatgccc atttccagaa agccaaagag     1080

aggcttgagg ccaagcaccg agagagaatg tcccaggtca tgagagaatg ggaagaggca     1140

gaacgtcaag caaagaactt gcctaaagct gataagaagg cagttatcca gcatttccag     1200

gagaaagtgg aatctttgga acaggaagca gccaacgaga gacagcagct ggtggagaca     1260

cacatggcca gagtggaagc catgctcaat gaccgccgcc gcctggccct ggagaactac     1320

atcaccgctc tgcaggctgt tcctcctcgg cctcgtcacg tgttcaatat gctaaagaag     1380

tatgtccgcg cagaacagaa ggacagacag cacaccctaa agcatttcga gcatgtgcgc     1440

atggtggatc ccaagaaagc cgctcagatc cggtcccagg ttatgacaca cctccgtgtg     1500

atttatgagc gcatgaatca gtctctctcc ctgctctaca acgtgcctgc agtggccgag     1560

gagattcagg atgaagttga tgagctgctt cagaaagagc aaaactattc agatgacgtc     1620

ttggccaaca tgattagtga accaaggatc agttacggaa acgatgctct catgccatct     1680

ttgaccgaaa cgaaaaccac cgtggagctc cttcccgtga atggagagtt cagcctggac     1740

gatctccagc cgtggcattc ttttggggct gactctgtgc cagccaacac agaaaacgaa     1800

gttgagcctg ttgatgcccg ccctgctgcc gaccgaggac tgaccactcg accaggttct     1860

gggttgacaa atatcaagac ggaggagatc tctgaagtga agatggatgc agaattccga     1920

catgactcag gatatgaagt tcatcatcaa aaattggtgt tctttgcaga agatgtgggt     1980

tcaaacaaa                                                             1989


<210>  5074
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  5074
caagcatttc atcttgggaa gtgccccaat cctccggtgc aggagaattt tgacgtgaat       60

aagtatctcg gaagatggta cgaaattgag aagatcccaa caacctttga gaatggacgc      120

tgcatccagg ccaactactc actaatggaa aacggaaaga tcaaagtgtt aaaccaggag      180

ttgagagctg atggaactgt gaatcaaatc gaaggtgaag ccaccccagt taacctcaca      240

gagcctgcca agctggaagt taagttttcc tggtttatgc catcggcacc gtactggatc      300

ctggccaccg actatgagaa ctatgccctc gtgtattcct gtacctgcat catccaactt      360

tttcacgtgg attttgcttg gatcttggca agaaacccta atctccctcc agaaacagtg      420

gactctctaa aaaatatcct gacttctaat aacattgatg tcaagaaaat gacggtcaca      480

gaccaggtga actgccccaa gctctcg                                          507


<210>  5075
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  5075
atgttgaccg agctggagaa agccttgaac tctatcatcg acgtctacca caagtactcc       60

ctgataaagg ggaatttcca tgccgtctac agggatgacc tgaagaaatt gctagagacc      120

gagtgtcctc agtatatcag gaaaaagggt gcagacgtct ggttcaaaga gttggatatc      180

aacactgatg gtgcagttaa cttccaggag ttcctcattc tggtgataaa gatgggcgtg      240

gcagcccaca aaaaaagcca tgaagaaagc cacaaagag                             279


<210>  5076
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  5076
tcaactcccc tgatgtcctg gccttggtct ccctctgctc tgcgcctgct gcagaggcct       60

ccggaggaac cggctgccca tgccaactgc cacagagtag cactgaacat ctccttccag      120

gagctgggct gggaacggtg gatcgtgtac cctcccagtt tcatcttcca ctactgtcat      180

ggtggttgtg ggctgcacat cccaccaaac ctgtcccttc cagtccctgg ggctccccct      240

accccagccc agccctactc cttgctgcca ggggcccagc cctgctgtgc tgctctccca      300

gggaccatga ggcccctaca tgtccgcacc acctcggatg gaggttactc tttcaagtat      360

gagacagtgc ccaaccttct cacgcagcac tgtgcttgta tc                         402


<210>  5077
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  5077
atggaggatc tttgtgtggc aaacacactc tttgccctca atttattcaa gcatctggca       60

aaagcaagcc ccacccagaa cctcttcctc tccccatgga gcatctcgtc caccatggcc      120

atggtctaca tgggctccag gggcagcacc gaagaccaga tggccaaggt gcttcagttt      180

aatgaagtgg gagccaatgc agttaccccc atgactccag agaactttac cagctgtggg      240

ttcatgcagc agatccagaa gggtagttat cctgatgcga ttttgcaggc acaagctgca      300

gataaaatcc attcatcctt ccgctctctc agctctgcaa tcaatgcatc cacagggaat      360

tatttactgg aaagtgtcaa taagctgttt ggtgagaagt ctgcgagctt ccgggaagaa      420

tatattcgac tctgtcagaa atattactcc tcagaacccc aggcagtaga cttcctagaa      480

tgtgcagaag aagctagaaa aaagatttat tcctgggtca agactcaaac caaaggcaaa      540

atcccaaact tgttacctga aggttctgta gatggggata ccaggatggt cctggtgaat      600

gctgtctact tcaaaggaaa gtggaaaact ccatttgaga agaaactaaa tgggctttat      660

cctttccgtg taaactcggc tcagcgcaca cctgtacaga tgatgtactt gcgtgaaaag      720

ctaaacattg gatacataga agacctaaag gctcagattc tagaactccc atatgctgga      780

gatgttagca tgttcttgtt gcttccagat gaaattgccg atgtgtccac tggcttggag      840

ctgctggaaa gtgaaataac ctatgacaaa ctcaacaagt ggaccagcaa agacaaaatg      900

gctgaagatg aagttgaggt atacataccc cagttcaaat tagaagagca ttatgaactc      960

agatccattc tgagaagcat gggcatggag gacgccttca acaagggacg ggccaatttc     1020

tcagggatgt cggagaggaa tgacctgttt ctttctgaag tgttccacca agccatggtg     1080

gatgtgaatg aggagggcac tgaagcagcc gctggcacag gaggtgttat gacagggaga     1140

actggacatg gaggcccaca gtttgtggca gatcatcctt ttctttttct tattatgcat     1200

aagataacca actgcatttt atttttcggc agattttcct caccc                     1245


<210>  5078
<211>  1137
<212>  DNA
<213>  Homo Sapiens

<400>  5078
gtgcaccatc ccccatccta cgtggcccac ctggcctcag acttcggggt gagggtgttt       60

cagcaggtgg cgcaggcctc caaggaccgc aacgtggttt tctcacccta tggggtggcc      120

tcggtgttgg ccatgctcca gctgacaaca ggaggagaaa cccagcagca gattcaagca      180

gctatgggat tcaagattga tgacaagggc atggcccccg ccctccggca tctgtacaag      240

gagctcatgg ggccatggaa caaggatgag atcagcacca cagacgcgat cttcgtccag      300

cgggatctga agctggtcca gggcttcatg ccccacttct tcaggctgtt ccggagcacg      360

gtcaagcaag tggacttttc agaggtggag agagccagat tcatcatcaa tgactgggtg      420

aagacacaca caaaaggtat gatcagcaac ttgcttggga aaggagccgt ggaccagctg      480

acacggctgg tgctggtgaa tgccctctac ttcaacggcc agtggaagac tcccttcccc      540

gactccagca cccaccgccg cctcttccac aaatcagacg gcagcactgt ctctgtgccc      600

atgatggctc agaccaacaa gttcaactat actgagttca ccacgcccga tggccattac      660

tacgacatcc tggaactgcc ctaccacggg gacaccctca gcatgttcat tgctgcccct      720

tatgaaaaag aggtgcctct ctctgccctc accaacattc tgagtgccca gctcatcagc      780

cactggaaag gcaacatgac caggctgccc cgcctcctgg ttctgcccaa gttctccctg      840

gagactgaag tcgacctcag gaagccccta gagaacctgg gaatgaccga catgttcaga      900

cagtttcagg ctgacttcac gagtctttca gaccaagagc ctctccacgt cgcgcaggcg      960

ctgcagaaag tgaagatcga ggtgaacgag agtggcacgg tggcctcctc atccacagct     1020

gtcatagtct cagcccgcat ggcccccgag gagatcatca tggacagacc cttcctcttt     1080

gtggtccggc acaaccccac aggaacagtc cttttcatgg gccaagtgat ggaaccc        1137


<210>  5079
<211>  1143
<212>  DNA
<213>  Homo Sapiens

<400>  5079
gagatgaaga agagagtcga ggacctccat gtaggtgcca cggtggcccc cagcagcaga       60

agggacttta cctttgacct ctacagggcc ttggcttccg ctgcccccag ccagaacatc      120

ttcttctccc ctgtgagcat ctccatgagc ctggccatgc tctccctggg ggctgggtcc      180

agcacaaaga tgcagatcct ggagggcctg ggcctcaacc tccagaaaag ctcagagaag      240

gagctgcaca gaggctttca gcagctcctt caggaactca accagcccag agatggcttc      300

cagctgagcc tcggcaatgc ccttttcacc gacctggtgg tagacctgca ggacaccttc      360

gtaagtgcca tgaagacgct gtacctggca gacactttcc ccaccaactt tagggactct      420

gcaggggcca tgaagcagat caatgattat gtggcaaagc aaacgaaggg caagattgtg      480

gacttgctta agaacctcga tagcaatgcg gtcgtgatca tggtgaatta catcttcttt      540

aaagctaagt gggagacaag cttcaaccac aaaggcaccc aagagcaaga cttctacgtg      600

acctcggaga ctgtggtgcg ggtacccatg atgagccgcg aggatcagta tcactacctc      660

ctggaccgga acctctcctg cagggtggtg ggggtcccct accaaggcaa tgccacggct      720

ttgttcattc tccccagtga gggaaagatg cagcaggtgg agaatggact gagtgagaaa      780

acgctgagga agtggcttaa gatgttcaaa aagaggcagc tcgagcttta ccttcccaaa      840

ttctccattg agggctccta tcagctggag aaagtcctcc ccagtctggg gatcagtaac      900

gtcttcacct cccatgctga tctgtccggc atcagcaacc actcaaatat ccaggtgtct      960

gagatggtgc acaaagctgt ggtggaggtg gacgagtcgg gaaccagagc agcggcagcc     1020

acggggacaa tcttcacttt caggtcggcc cgcctgaact ctcagaggct agtgttcaac     1080

aggccctttc tgatgttcat tgtggataac aacatcctct tccttggcaa agtgaaccgc     1140

ccc                                                                   1143


<210>  5080
<211>  1434
<212>  DNA
<213>  Homo Sapiens

<400>  5080
aatccaaatg ctaccagctc cagctcccag gatccagaga gtttgcaaga cagaggcgaa       60

gggaaggtcg caacaacagt tatctccaag atgctattcg ttgaacccat cctggaggtt      120

tccagcttgc cgacaaccaa ctcaacaacc aattcagcca ccaaaataac agctaatacc      180

actgatgaac ccaccacaca acccaccaca gagcccacca cccaacccac catccaaccc      240

acccaaccaa ctacccagct cccaacagat tctcctaccc agcccactac tgggtccttc      300

tgcccaggac ctgttactct ctgctctgac ttggagagtc attcaacaga ggccgtgttg      360

ggggatgctt tggtagattt ctccctgaag ctctaccacg ccttctcagc aatgaagaag      420

gtggagacca acatggcctt ttccccattc agcatcgcca gcctccttac ccaggtcctg      480

ctcggggctg gggagaacac caaaacaaac ctggagagca tcctctctta ccccaaggac      540

ttcacctgtg tccaccaggc cctgaagggc ttcacgacca aaggtgtcac ctcagtctct      600

cagatcttcc acagcccaga cctggccata agggacacct ttgtgaatgc ctctcggacc      660

ctgtacagca gcagccccag agtcctaagc aacaacagtg acgccaactt ggagctcatc      720

aacacctggg tggccaagaa caccaacaac aagatcagcc ggctgctaga cagtctgccc      780

tccgataccc gccttgtcct cctcaatgct atctacctga gtgccaagtg gaagacaaca      840

tttgatccca agaaaaccag aatggaaccc tttcacttca aaaactcagt tataaaagtg      900

cccatgatga atagcaagaa gtaccctgtg gcccatttca ttgaccaaac tttgaaagcc      960

aaggtggggc agctgcagct ctcccacaat ctgagtttgg tgatcctggt accccagaac     1020

ctgaaacatc gtcttgaaga catggaacag gctctcagcc cttctgtttt caaggccatc     1080

atggagaaac tggagatgtc caagttccag cccactctcc taacactacc ccgcatcaaa     1140

gtgacgacca gccaggatat gctctcaatc atggagaaat tggaattctt cgatttttct     1200

tatgacctta acctgtgtgg gctgacagag gacccagatc ttcaggtttc tgcgatgcag     1260

caccagacag tgctggaact gacagagact ggggtggagg cggctgcagc ctccgccatc     1320

tctgtggccc gcaccctgct ggtctttgaa gtgcagcagc ccttcctctt catgctctgg     1380

gaccagcagc acaagttccc tgtcttcatg gggcgagtat atgaccccag ggcc           1434


<210>  5081
<211>  1923
<212>  DNA
<213>  Homo Sapiens

<400>  5081
gaagagaaac cctgtggttt tcctcatgtg gaaaatggaa gaattgccca atattactat       60

acttttaaaa gcttttactt tccaatgagc atagacaaaa aattgtcatt tttctgcttg      120

gctggttata ccactgaaag tggaagacaa gaagagcaaa ccacgtgtac aacagaaggc      180

tggtctccag agccaaggtg cttcaaaaaa tgcactaagc ctgacctgag taatggttac      240

atctctgatg taaagttatt gtataaaatt caagagaaca tgcgttatgg ttgcgcttca      300

gggtacaaaa ccactggagg gaaggatgaa gaagtggttc aatgtctctc tgatggatgg      360

tcttctcaac caacctgtag gaaagaacat gaaacatgtt tggctcctga attatataat      420

ggaaattatt ccacaacaca gaaaacattc aaagtgaagg acaaagtaca atacgaatgt      480

gctactggct actacacagc tggaggaaag aagacagagg aggtagaatg tctcacatac      540

ggatggtctc tcacaccaaa atgtaccaaa ttaaagtgct cttctttaag attaattgaa      600

aatggttatt ttcatcctgt aaagcaaacc tatgaagaag gagatgtcgt tcagtttttc      660

tgtcatgaaa attattatct aagtggatct gatttaattc aatgctataa ctttggttgg      720

tacccagaat ctcctgtatg cgaaggaaga agaaacagat gtcctcctcc acctctgccc      780

ataaactcca aaattcaaac acattcaaca acttatcgtc atggagaaat agttcatata      840

gaatgtgaac ttaattttga gatccatggg tcagcagaaa tacgttgtga agatggaaaa      900

tggacagaac ctccaaaatg cattgaagga caggagaagg tagcctgtga ggaaccaccc      960

ttcattgaaa atggtgcagc aaatttacac tctaagattt attacaatgg ggataaagtg     1020

acatatgcat gtaaaagcgg ctaccttctc catggatcga atgagataac ttgtaatcgt     1080

ggaaaatgga cacttcctcc tgagtgtgtt gaaaataatg agaattgtaa gcatcctcct     1140

gttgtaatga atggggctgt tgcagacggg atattggcaa gctatgcaac aggatcctca     1200

gtggaatata gatgcaatga atattactta ctgaggggat caaaaatatc tcgttgcgaa     1260

caaggaaaat ggtcatcccc acctgtttgc ttggaaccat gtactgttaa tgtggattac     1320

atgaacagaa ataacataga aatgaagtgg aaatatgaag ggaaagtctt acatggagat     1380

ttaatagatt ttgtatgtaa acagggatat gacttatctc cattaacccc attgtctgaa     1440

ttatctgtgc agtgcaacag aggagaagtg aaatatcctt tatgtactag aaaagaatct     1500

aaaggaatgt gcacatctcc tcctcttatt aaacatggag tcattattag ttcaacagta     1560

gacacctatg aaaatggctc ttcagtagaa tacagatgtt ttgatcacca tttcctagaa     1620

ggatctaggg aggcctattg tttagatgga atgtggacta caccaccatt gtgtttagag     1680

ccatgcacat tatcttttac tgaaatggaa aagaataatt tacttctgaa atgggatttt     1740

gacaatagac cacacatttt gcatggtgaa tatattgagt ttatttgtag aggagatact     1800

tatccagctg aattatatat tactggatct atacttagaa tgcaatgtga cagagggcag     1860

ttaaaatatc caagatgtat tccaagacaa agcactctgt cttatcaaga acccttaaga     1920

aca                                                                   1923


<210>  5082
<211>  1743
<212>  DNA
<213>  Homo Sapiens

<400>  5082
gtgacttgcc cggagcagga caaataccgc accatcaccg ggatgtgcaa caacagacgc       60

agccccacgc tgggggcctc caaccgtgcc tttgtgcgct ggctgccggc ggagtatgag      120

gacggcttct ctcttcccta cggctggacg cccggggtca agcgcaacgg cttcccggtg      180

gctctggctc gcgcggtctc caacgagatc gtgcgcttcc ccactgatca gctgactccg      240

gaccaggagc gctcactcat gttcatgcaa tggggccagc tgttggacca cgacctcgac      300

ttcacccctg agccggccgc ccgggcctcc ttcgtcactg gcgtcaactg cgagaccagc      360

tgcgttcagc agccgccctg cttcccgctc aagatcccgc ccaatgaccc ccgcatcaag      420

aaccaagccg actgcatccc gttcttccgc tcctgcccgg cttgccccgg gagcaacatc      480

accatccgca accagatcaa cgcgctcact tccttcgtgg acgccagcat ggtgtacggc      540

agcgaggagc ccctggccag gaacctgcgc aacatgtcca accagctggg gctgctggcc      600

gtcaaccagc gcttccaaga caacggccgg gccctgctgc cctttgacaa cctgcacgat      660

gacccctgtc tcctcaccaa ccgctcagcg cgcatcccct gcttcctggc aggggacacc      720

cgttccagtg agatgcccga gctcacctcc atgcacaccc tcttacttcg ggagcacaac      780

cggctggcca cagagctcaa gagcctgaac cctaggtggg atggggagag gctctaccag      840

gaagcccgga agatcgtggg ggccatggtc cagatcatca cttaccggga ctacctgccc      900

ctggtgctgg ggccaacggc catgaggaag tacctgccca cgtaccgttc ctacaatgac      960

tcagtggacc cacgcatcgc caacgtcttc accaatgcct tccgctacgg ccacaccctc     1020

atccaaccct tcatgttccg cctggacaat cggtaccagc ccatggaacc caacccccgt     1080

gtccccctca gcagggtctt ttttgcctcc tggagggtcg tgctggaagg tggcattgac     1140

cccatcctcc ggggcctcat ggccacccct gccaagctga atcgtcagaa ccaaattgca     1200

gtggatgaga tccgggagcg attgtttgag caggtcatga ggattgggct ggacctgcct     1260

gctctgaaca tgcagcgcag cagggaccac ggcctcccag gatacaatgc ctggaggcgc     1320

ttctgtgggc tcccgcagcc tgaaactgtg ggccagctgg gcacggtgct gaggaacctg     1380

aaattggcga ggaaactgat ggagcagtat ggcacgccca acaacatcga catctggatg     1440

ggcggcgtgt ccgagcctct gaagcgcaaa ggccgcgtgg gcccactcct cgcctgcatc     1500

atcggtaccc agttcaggaa gctccgggat ggtgatcggt tttggtggga gaacgagggt     1560

gtgttcagca tgcagcagcg acaggccctg gcccagatct cattgccccg gatcatctgc     1620

gacaacacag gcatcaccac cgtgtctaag aacaacatct tcatgtccaa ctcatatccc     1680

cgggactttg tcaactgcag tacacttcct gcattgaacc tggcttcctg gagggaagcc     1740

tcc                                                                   1743


<210>  5083
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  5083
ttagtgccag agaaagagaa agaccccaag tactggcgag accaagcgca agagacactg       60

aaatatgccc tggagcttca gaagctcaac accaacgtgg ctaagaatgt catcatgttc      120

ctgggagatg ggatgggtgt ctccacagtg acggctgccc gcatcctcaa gggtcagctc      180

caccacaacc ctggggagga gaccaggctg gagatggaca agttcccctt cgtggccctc      240

tccaagacgt acaacaccaa tgcccaggtc cctgacagcg ccggcaccgc caccgcctac      300

ctgtgtgggg tgaaggccaa tgagggcacc gtgggggtaa gcgcagccac tgagcgttcc      360

cggtgcaaca ccacccaggg gaacgaggtc acctccatcc tgcgctgggc caaggacgct      420

gggaaatctg tgggcattgt gaccaccacg agagtgaacc atgccacccc cagcgccgcc      480

tacgcccact cggctgaccg ggactggtac tcagacaacg agatgccccc tgaggccttg      540

agccagggct gtaaggacat cgcctaccag ctcatgcata acatcaggga cattgacgtg      600

atcatggggg gtggccggaa atacatgtac cccaagaata aaactgatgt ggagtatgag      660

agtgacgaga aagccagggg cacgaggctg gacggcctgg acctcgttga cacctggaag      720

agcttcaaac cgagacacaa gcactcccac ttcatctgga accgcacgga actcctgacc      780

cttgaccccc acaatgtgga ctacctattg ggtctcttcg agccggggga catgcagtac      840

gagctgaaca ggaacaacgt gacggacccg tcactctccg agatggtggt ggtggccatc      900

cagatcctgc ggaagaaccc caaaggcttc ttcttgctgg tggaaggagg cagaattgac      960

cacgggcacc atgaaggaaa agccaagcag gccctgcatg aggcggtgga gatggaccgg     1020

gccatcgggc aggcaggcag cttgacctcc tcggaagaca ctctgaccgt ggtcactgcg     1080

gaccattccc acgtcttcac atttggtgga tacacccccc gtggcaactc tatctttggt     1140

ctggccccca tgctgagtga cacagacaag aagcccttca ctgccatcct gtatggcaat     1200

gggcctggct acaaggtggt gggcggtgaa cgagagaatg tctccatggt ggactatgct     1260

cacaacaact accaggcgca gtctgctgtg cccctgcgcc acgagaccca cggcggggag     1320

gacgtggccg tcttctccaa gggccccatg gcgcacctgc tgcacggcgt ccacgagcag     1380

aactacgtcc cccacgtgat ggcgtatgca gcctgcatcg gggccaacct cggccactgt     1440

gctcctgcca gc                                                         1452


<210>  5084
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  5084
atcatcccag ttgaggagga gaacccggac ttctggaacc gccaggcagc cgaggccctg       60

ggtgccgcca agaagctgca gcctgcacag acagccgcca agaacctcat catcttcctg      120

ggtgacggga tgggggtgtc tacggtgaca gctgccagga tcctaaaagg gcagaagaag      180

gacaaactgg ggcctgagac cttcctggcc atggaccgct tcccgtacgt ggctctgtcc      240

aagacataca gtgtagacaa gcatgtgcca gacagtggag ccacagccac ggcctacctg      300

tgcggggtca agggcaactt ccagaccatt ggcttgagtg cagccgcccg ctttaaccag      360

tgcaacacga cacgcggcaa cgaggtcatc tccgtgatga atcgggccaa gaaagcagga      420

aagtcagtgg gagtggtaac caccacacgg gtgcagcatg cctcgccagc cggcgcctac      480

gcccacacgg tgaaccgcaa ctggtactcg gatgccgacg tgcctgcctc ggcccgccag      540

gaggggtgcc aggacatcgc cacgcagctc atctccaaca tggacattga tgtgatccta      600

ggtggaggcc gaaagtacat gtttcccatg gggaccccag accctgagta cccagatgac      660

tacagccaag gtgggaccag gctggacggg aagaatctgg tgcaggaatg gctggcgaag      720

cgccagggtg cccggtacgt gtggaaccgc actgagctca tgcaggcttc cctggacccg      780

tctgtgaccc atctcatggg tctctttgag cctggagaca tgaaatacga gatccaccga      840

gactccacac tggacccctc cctgatggag atgacagagg ctgccctgcg cctgctgagc      900

aggaaccccc gcggcttctt cctcttcgtg gagggtggtc gcatcgacca tggtcatcat      960

gaaagcaggg cttaccgggc actgactgag acgatcatgt tcgacgacgc cattgagagg     1020

gcgggccagc tcaccagcga ggaggacacg ctgagcctcg tcactgccga ccactcccac     1080

gtcttctcct tcggaggcta ccccctgcga gggagctcca tcttcgggct ggcccctggc     1140

aaggcccggg acaggaaggc ctacacggtc ctcctatacg gaaacggtcc aggctatgtg     1200

ctcaaggacg gcgcccggcc ggatgttacc gagagcgaga gcgggagccc cgagtatcgg     1260

cagcagtcag cagtgcccct ggacggagag acccacgcag gcgaggacgt ggcggtgttc     1320

gcgcgcggcc cgcaggcgca cctggttcac ggcgtgcagg agcagacctt catagcgcac     1380

gtcatggcct tcgccgcctg cctggagccc tacaccgcct gcgacctggc gccccgcgcc     1440

ggcaccaccg ac                                                         1452


<210>  5085
<211>  555
<212>  DNA
<213>  Homo Sapiens

<400>  5085
tacagccccc ggacccctga ccgggtctca gaagcagata tccagaggct gcttcatggt       60

gttatggagc aattgggcat tgccaggccc cgagtggaat atccagctca ccaggccatg      120

aatcttgtgg gcccccagag cattgaaggt ggagctcatg aaggacttca gcatttgggt      180

ccttttggca acatccccaa catcgtggca gagttgactg gagacaacat tcctaaggac      240

tttagtgagg atcaggggta cccagaccct ccaaatccct gtcctgttgg aaaaacagat      300

gatggatgtc tagaaaacac ccctgacact gcagagttca gtcgagagtt ccagttgcac      360

cagcatctct ttgatccgga acatgactat ccaggcttgg gcaagtggaa caagaaactc      420

ctttacgaga agatgaaggg aggagagaga cgaaagcgga ggagtgtcaa tccatatcta      480

caaggacaga gactggataa tgttgttgca aagaagtctg tcccccattt ttcagatgag      540

gataaggatc cagag                                                       555


<210>  5086
<211>  1185
<212>  DNA
<213>  Homo Sapiens

<400>  5086
gcatcacctg aaggcaaagt aacagcctgc cattcatccc aaccaaatgc cactctctac       60

aagatgtcat ccattaatgc tgactttgca ttcaatctgt accggaggtt cactgtggag      120

accccagata agaacatctt cttttcccct gtgagcattt ctgcagcttt ggttatgctt      180

tcctttgggg cctgctgcag cacccaaact gagattgtgg agaccttggg gttcaacctc      240

acagacactc caatggtaga gatccagcat ggcttccagc atctgatctg ttcactgaat      300

tttccaaaga aggaactgga attgcagata ggaaatgccc tcttcattgg caagcatctg      360

aaaccactgg caaagttctt gaatgatgtc aagaccctct atgagactga agtcttttct      420

accgacttct ccaacatttc tgcagccaag caggagatta acagtcatgt ggagatgcaa      480

accaaaggga aagttgtggg tctaattcaa gacctcaagc caaacaccat catggtctta      540

gtgaactata ttcactttaa agcccagtgg gcaaatcctt ttgatccatc caagacagaa      600

gacagttcca gcttcttaat agacaagacc accactgttc aagtgcccat gatgcaccag      660

atggaacaat actatcacct agtggatatg gaattgaact gcacagttct gcaaatggac      720

tacagcaaga atgctctggc actctttgtt cttcccaagg agggacagat ggagtcagtg      780

gaagctgcca tgtcatctaa aacactgaag aagtggaacc gcttactaca gaagggatgg      840

gttgacttgt ttgttccaaa gttttccatt tctgccacat atgaccttgg agccacactt      900

ttgaagatgg gcattcagca tgcctattct gaaaatgctg atttttctgg actcacagag      960

gacaatggtc tgaaactttc caatgctgcc cataaggctg tgctgcacat tggtgaaaag     1020

ggaactgaag ctgcagctgt ccctgaagtt gaactttcgg atcagcctga aaacactttc     1080

ctacacccta ttatccaaat tgatagatct ttcatgttgt tgattttgga gagaagcaca     1140

aggagtattc tctttctagg gaaagttgtg aacccaacgg aagcg                     1185


<210>  5087
<211>  1440
<212>  DNA
<213>  Homo Sapiens

<400>  5087
gggagcaaag gcccgctgga tcagctagag aaaggagggg aaactgctca gtctgcagat       60

ccccagtggg agcagttaaa taacaaaaac ctgagcatgc ctcttctccc tgccgacttc      120

cacaaggaaa acaccgtcac caacgactgg attccagagg gggaggagga cgacgactat      180

ctggacctgg agaagatatt cagtgaagac gacgactaca tcgacatcgt cgacagtctg      240

tcagtttccc cgacagactc tgatgtgagt gctgggaaca tcctccagct ttttcatggc      300

aagagccgga tccagcgtct taacatcctc aacgccaagt tcgctttcaa cctctaccga      360

gtgctgaaag accaggtcaa cactttcgat aacatcttca tagcacccgt tggcatttct      420

actgcgatgg gtatgatttc cttaggtctg aagggagaga cccatgaaca agtgcactcg      480

attttgcatt ttaaagactt tgttaatgcc agcagcaagt atgaaatcac gaccattcat      540

aatctcttcc gtaagctgac tcatcgcctc ttcaggagga attttgggta cacactgcgg      600

tcagtcaatg acctttatat ccagaagcag tttccaatcc tgcttgactt caaaactaaa      660

gtaagagagt attactttgc tgaggcccag atagctgact tctcagaccc tgccttcata      720

tcaaaaacca acaaccacat catgaagctc accaagggcc tcataaaaga tgctctggag      780

aatatagacc ctgctaccca gatgatgatt ctcaactgca tctacttcaa aggatcctgg      840

gtgaataaat tcccagtgga aatgacacac aaccacaact tccggctgaa tgagagagag      900

gtagttaagg tttccatgat gcagaccaag gggaacttcc tcgcagcaaa tgaccaggag      960

ctggactgcg acatcctcca gctggaatac gtggggggca tcagcatgct aattgtggtc     1020

ccacacaaga tgtctgggat gaagaccctc gaagcgcaac tgacaccccg ggtggtggag     1080

agatggcaaa aaagcatgac aaacagaact cgagaagtgc ttctgccgaa attcaagctg     1140

gagaagaact acaatctagt ggagtccctg aagttgatgg ggatcaggat gctgtttgac     1200

aaaaatggca acatggcagg catctcagac caaaggatcg ccatcgacct gttcaagcac     1260

caaggcacga tcacagtgaa cgaggaaggc acccaagcca ccactgtgac cacggtgggg     1320

ttcatgccgc tgtccaccca agtccgcttc actgtcgacc gcccctttct tttcctcatc     1380

tacgagcatc gcaccagctg cctgctcttc atgggaagag tggccaaccc cagcaggtcc     1440


<210>  5088
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  5088
agggagacca tagaaagcct ttcaagcagt gaggaatcta ttacagaata caagcagaaa       60

gttgagaagg ttaaacatga ggaccagcag caaggagagg atgaacacca ggataaaatc      120

tacccctctt tccagccaca gcctctgatc tatccattcg ttgaacctat cccctatggt      180

tttcttccac aaaacattct gcctcttgct cagcctgctg tggtgctgcc tgtccctcag      240

cctgaaataa tggaagtccc taaagctaaa gacactgtct acactaaggg cagagtgatg      300

cctgtcctta aatctccaac gatacccttt tttgaccctc aaatcccaaa actcactgat      360

cttgaaaatc tgcatcttcc tctgcctctg ctccagccct tgatgcagca ggtccctcag      420

cctattcctc agactcttgc acttccccct cagcccctgt ggtctgttcc tcagcccaaa      480

gtcctgccta tcccccagca agtggtgccc taccctcaga gagctgtgcc tgttcaagcc      540

cttctgctca accaagaact tctacttaac cccacccacc agatctaccc tgtgactcag      600

ccacttgccc cagttcataa ccccattagt gtc                                   633


<210>  5089
<211>  1119
<212>  DNA
<213>  Homo Sapiens

<400>  5089
aggagtgacc aggagccgct gtacccagtg caggtcagct ctgcggacgc tcggctcatg       60

gtctttgaca agacggaagg gacgtggcgg ctgctgtgct cctcgcgctc caacgccagg      120

gtagccggac tcagctgcga ggagatgggc ttcctcaggg cactgaccca ctccgagctg      180

gacgtgcgaa cggcgggcgc caatggcacg tcgggcttct tctgtgtgga cgaggggagg      240

ctgccccaca cccagaggct gctggaggtc atctccgtgt gtgattgccc cagaggccgt      300

ttcttggccg ccatctgcca agactgtggc cgcaggaagc tgcccgtgga ccgcatcgtg      360

ggaggccggg acaccagctt gggccggtgg ccgtggcaag tcagccttcg ctatgatgga      420

gcacacctct gtgggggatc cctgctctcc ggggactggg tgctgacagc cgcccattgc      480

ttcccggagc ggaaccgggt cctgtcccga tggcgagtgt ttgccggtgc cgtggcccag      540

gcctctcccc acggtctgca gctgggggtg caggctgtgg tctaccacgg gggctatctt      600

ccctttcggg accccaacag cgaggagaac agcaacgata ttgccctggt ccacctctcc      660

agtcccctgc ccctcacaga atacatccag cctgtgtgcc tcccagctgc cggccaggcc      720

ctggtggatg gcaagatctg taccgtgacg ggctggggca acacgcagta ctatggccaa      780

caggccgggg tactccagga ggctcgagtc cccataatca gcaatgatgt ctgcaatggc      840

gctgacttct atggaaacca gatcaagccc aagatgttct gtgctggcta ccccgagggt      900

ggcattgatg cctgccaggg cgacagcggt ggtccctttg tgtgtgagga cagcatctct      960

cggacgccac gttggcggct gtgtggcatt gtgagttggg gcactggctg tgccctggcc     1020

cagaagccag gcgtctacac caaagtcagt gacttccggg agtggatctt ccaggccata     1080

aagactcact ccgaagccag cggcatggtg acccagctc                            1119


<210>  5090
<211>  1407
<212>  DNA
<213>  Homo Sapiens

<400>  5090
ggaaaggtgc tggtgtggcc cacagaattc agccactgga tgaatataaa gacaatcctg       60

gatgaacttg tccagagagg tcatgaggtg actgtattgg catcttcagc ttccatttct      120

ttcgatccca acagcccatc tactcttaaa tttgaagttt atcctgtatc tttaactaaa      180

actgagtttg aggatattat caagcagctg gttaagagat gggcagaact tccaaaagac      240

acattttggt catatttttc acaagtacaa gaaatcatgt ggacatttaa tgacatactt      300

agaaagttct gtaaggatat agtttcaaat aagaaactta tgaagaaact acaggagtca      360

agatttgatg ttgttcttgc agatgctgtt ttcccctttg gtgagctgct ggccgagtta      420

cttaaaatac cctttgtcta cagcctccgc ttctctcctg gctacgcaat tgaaaagcat      480

agtggaggac ttctgttccc tccttcctat gtgcctgttg ttatgtcaga actaagtgac      540

caaatgactt tcatagagag ggtaaaaaat atgatctatg tgctttattt tgaattttgg      600

ttccaaatat ttgacatgaa gaagtgggat cagttctaca gtgaagttct aggaagaccc      660

actacgttat ctgagacaat ggcaaaagct gacatatggc ttattcgaaa ctactgggat      720

tttcaatttc ctcacccact cttaccaaat gttgagttcg ttggaggact ccactgcaaa      780

cctgccaaac ccctaccgaa ggaaatggaa gagtttgtcc agagctctgg agaaaatggt      840

gttgtggtgt tttctctggg gtcgatggtc agtaacacgt cagaagaaag ggccaatgta      900

attgcatcag cccttgccaa gatcccacaa aaggttctgt ggagatttga tgggaataaa      960

ccagatactt taggactcaa tactcggctg tacaagtgga taccccagaa tgatcttctt     1020

ggtcacccaa aaaccagagc ttttataact catggtggag ccaatggcat ctatgaggca     1080

atctaccatg gaatccctat ggtgggcgtt ccattgtttg cagatcaacc tgataacatt     1140

gcacacatga aggccaaggg agcagctgtt agtttggact tccacacaat gtcgagtact     1200

gacttactca atgcactgaa gacagtaatt aatgatcctt tatataaaga gaatgctatg     1260

aaattatcaa gaattcatca tgatcaacca gtgaagcccc ttgatcgagc agtcttctgg     1320

attgaatttg tcatgcgcca taaaggagcc aagcaccttc gggttgcagc ccacgacctc     1380

acctggttcc agtaccactc tttggat                                         1407


<210>  5091
<211>  1722
<212>  DNA
<213>  Homo Sapiens

<400>  5091
gaagatgaca tcataattgc aacaaagaat ggaaaagtca gagggatgaa cttgacagtt       60

tttggtggca cggtaacagc ctttcttgga attccctatg cacagccacc tcttggtaga      120

cttcgattca aaaagccaca gtctctgacc aagtggtctg atatttggaa tgccacaaaa      180

tatgcaaatt cttgctgtca gaacatagat caaagttttc caggcttcca tggatcagag      240

atgtggaacc caaacactga cctcagtgaa gactgtttat atctaaatgt atggattcca      300

gcacctaaac caaaaaatgc cactgtattg atatggattt atggtggtgg ttttcaaact      360

ggaacatcat ctttacatgt ttatgatggc aagtttctgg ctcgggttga aagagttatt      420

gtagtgtcaa tgaactatag ggtgggtgcc ctaggattct tagctttgcc aggaaatcct      480

gaggctccag ggaacatggg tttatttgat caacagttgg ctcttcagtg ggttcaaaaa      540

aatatagcag cctttggtgg aaatcctaaa agtgtaactc tctttggaga aagtgcagga      600

gcagcttcag ttagcctgca tttgctttct cctggaagcc attcattgtt caccagagcc      660

attctgcaaa gtggatcctt taatgctcct tgggcggtaa catctcttta tgaagctagg      720

aacagaacgt tgaacttagc taaattgact ggttgctcta gagagaatga gactgaaata      780

atcaagtgtc ttagaaataa agatccccaa gaaattcttc tgaatgaagc atttgttgtc      840

ccctatggga ctcctttgtc agtaaacttt ggtccgaccg tggatggtga ttttctcact      900

gacatgccag acatattact tgaacttgga caatttaaaa aaacccagat tttggtgggt      960

gttaataaag atgaagggac agctttttta gtctatggtg ctcctggctt cagcaaagat     1020

aacaatagta tcataactag aaaagaattt caggaaggtt taaaaatatt ttttccagga     1080

gtgagtgagt ttggaaagga atccatcctt tttcattaca cagactgggt agatgatcag     1140

agacctgaaa actaccgtga ggccttgggt gatgttgttg gggattataa tttcatatgc     1200

cctgccttgg agttcaccaa gaagttctca gaatggggaa ataatgcctt tttctactat     1260

tttgaacacc gatcctccaa acttccgtgg ccagaatgga tgggagtgat gcatggctat     1320

gaaattgaat ttgtctttgg tttacctctg gaaagaagag ataattacac aaaagccgag     1380

gaaattttga gtagatccat agtgaaacgg tgggcaaatt ttgcaaaata tgggaatcca     1440

aatgagactc agaacaatag cacaagctgg cctgtcttca aaagcactga acaaaaatat     1500

ctaaccttga atacagagtc aacaagaata atgacgaaac tacgtgctca acaatgtcga     1560

ttctggacat cattttttcc aaaagtcttg gaaatgacag gaaatattga tgaagcagaa     1620

tgggagtgga aagcaggatt ccatcgctgg aacaattaca tgatggactg gaaaaatcaa     1680

tttaacgatt acactagcaa gaaagaaagt tgtgtgggtc tc                        1722


<210>  5092
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  5092
ctggacaatg gattggcaag gacgcctacc atgggctggc tgcactggga gcgcttcatg       60

tgcaaccttg actgccagga agagccagat tcctgcatca gtgagaagct cttcatggag      120

atggcagagc tcatggtctc agaaggctgg aaggatgcag gttatgagta cctctgcatt      180

gatgactgtt ggatggctcc ccaaagagat tcagaaggca gacttcaggc agaccctcag      240

cgctttcctc atgggattcg ccagctagct aattatgttc acagcaaagg actgaagcta      300

gggatttatg cagatgttgg aaataaaacc tgcgcaggct tccctgggag ttttggatac      360

tacgacattg atgcccagac ctttgctgac tggggagtag atctgctaaa atttgatggt      420

tgttactgtg acagtttgga aaatttggca gatggttata agcacatgtc cttggccctg      480

aataggactg gcagaagcat tgtgtactcc tgtgagtggc ctctttatat gtggcccttt      540

caaaagccca attatacaga aatccgacag tactgcaatc actggcgaaa ttttgctgac      600

attgatgatt cctggaaaag tataaagagt atcttggact ggacatcttt taaccaggag      660

agaattgttg atgttgctgg accagggggt tggaatgacc cagatatgtt agtgattggc      720

aactttggcc tcagctggaa tcagcaagta actcagatgg ccctctgggc tatcatggct      780

gctcctttat tcatgtctaa tgacctccga cacatcagcc ctcaagccaa agctctcctt      840

caggataagg acgtaattgc catcaatcag gaccccttgg gcaagcaagg gtaccagctt      900

agacagggag acaactttga agtgtgggaa cgacctctct caggcttagc ctgggctgta      960

gctatgataa accggcagga gattggtgga cctcgctctt ataccatcgc agttgcttcc     1020

ctgggtaaag gagtggcctg taatcctgcc tgcttcatca cacagctcct ccctgtgaaa     1080

aggaagctag ggttctatga atggacttca aggttaagaa gtcacataaa tcccacaggc     1140

actgttttgc ttcagctaga aaatacaatg cagatgtcat taaaagactt actt           1194


<210>  5093
<211>  174
<212>  DNA
<213>  Homo Sapiens

<400>  5093
gtatcgcaga gaacggatgg cgagtcccga gcgcacctgg gcgccctgct ggcaagatac       60

atccagcagg cccggaaagc tccttctgga cgaatgtcca tcgttaagaa cctgcagaac      120

ctggacccca gccacaggat aagtgaccgg gactacatgg gctggatgga tttt            174


<210>  5094
<211>  2265
<212>  DNA
<213>  Homo Sapiens

<400>  5094
gccactgcgt cgcggggggc gtcccaggcg ggggcgcccc aggggcgggt gcccgaggcg       60

cggcccaaca gcatggtggt ggaacacccc gagttcctca aggcagggaa ggagcctggc      120

ctgcagatct ggcgtgtgga gaagttcgat ctggtgcccg tgcccaccaa cctttatgga      180

gacttcttca cgggcgacgc ctacgtcatc ctgaagacag tgcagctgag gaacggaaat      240

ctgcagtatg acctccacta ctggctgggc aatgagtgca gccaggatga gagcggggcg      300

gccgccatct ttaccgtgca gctggatgac tacctgaacg gccgggccgt gcagcaccgt      360

gaggtccagg gcttcgagtc ggccaccttc ctaggctact tcaagtctgg cctgaagtac      420

aagaaaggag gtgtggcatc aggattcaag cacgtggtac ccaacgaggt ggtggtgcag      480

agactcttcc aggtcaaagg gcggcgtgtg gtccgtgcca ccgaggtacc tgtgtcctgg      540

gagagcttca acaatggcga ctgcttcatc ctggacctgg gcaacaacat ccaccagtgg      600

tgtggttcca acagcaatcg gtatgaaaga ctgaaggcca cacaggtgtc caagggcatc      660

cgggacaacg agcggagtgg ccgggcccga gtgcacgtgt ctgaggaggg cactgagccc      720

gaggcgatgc tccaggtgct gggccccaag ccggctctgc ctgcaggtac cgaggacacc      780

gccaaggagg atgcggccaa ccgcaagctg gccaagctct acaaggtctc caatggtgca      840

gggaccatgt ccgtctccct cgtggctgat gagaacccct tcgcccaggg ggccctgaag      900

tcagaggact gcttcatcct ggaccacggc aaagatggga aaatctttgt ctggaaaggc      960

aagcaggcaa acacggagga gaggaaggct gccctcaaaa cagcctctga cttcatcacc     1020

aagatggact accccaagca gactcaggtc tcggtccttc ctgagggcgg tgagacccca     1080

ctgttcaagc agttcttcaa gaactggcgg gacccagacc agacagatgg cctgggcttg     1140

tcctaccttt ccagccatat cgccaacgtg gagcgggtgc ccttcgacgc cgccaccctg     1200

cacacctcca ctgccatggc cgcccagcac ggcatggatg acgatggcac aggccagaaa     1260

cagatctgga gaatcgaagg ttccaacaag gtgcccgtgg accctgccac atatggacag     1320

ttctatggag gcgacagcta catcattctg tacaactacc gccatggtgg ccgccagggg     1380

cagataatct ataactggca gggtgcccag tctacccagg atgaggtcgc tgcatctgcc     1440

atcctgactg ctcagctgga tgaggagctg ggaggtaccc ctgtccagag ccgtgtggtc     1500

caaggcaagg agcccgccca cctcatgagc ctgtttggtg ggaagcccat gatcatctac     1560

aagggcggca cctcccgcga gggcgggcag acagcccctg ccagcacccg cctcttccag     1620

gtccgcgcca acagcgctgg agccacccgg gctgttgagg tattgcctaa ggctggtgca     1680

ctgaactcca acgatgcctt tgttctgaaa accccctcag ccgcctacct gtgggtgggt     1740

acaggagcca gcgaggcaga gaagacgggg gcccaggagc tgctcagggt gctgcgggcc     1800

caacctgtgc aggtggcaga aggcagcgag ccagatggct tctgggaggc cctgggcggg     1860

aaggctgcct accgcacatc cccacggctg aaggacaaga agatggatgc ccatcctcct     1920

cgcctctttg cctgctccaa caagattgga cgttttgtga tcgaagaggt tcctggtgag     1980

ctcatgcagg aagacctggc aacggatgac gtcatgcttc tggacacctg ggaccaggtc     2040

tttgtctggg ttggaaagga ttctcaagaa gaagaaaaga cagaagcctt gacttctgct     2100

aagcggtaca tcgagacgga cccagccaat cgggatcggc ggacgcccat caccgtggtg     2160

aagcaaggct ttgagcctcc ctcctttgtg ggctggttcc ttggctggga tgatgattac     2220

tggtctgtgg accccttgga cagggccatg gctgagctgg ctgcc                     2265


<210>  5095
<211>  1527
<212>  DNA
<213>  Homo Sapiens

<400>  5095
aaaatccaaa tccagcgctc tggtcatctg aacctctacc tgctcctgga ctgttcgcag       60

agtgtgtcgg aaaatgactt tctcatcttc aaggagagcg cctccctcat ggtggacagg      120

atcttcagct ttgagatcaa tgtgagcgtt gccattatca cctttgcctc agagcccaaa      180

gtcctcatgt ctgtcctgaa cgacaactcc cgggatatga ctgaggtgat cagcagcctg      240

gaaaatgcca actataaaga tcatgaaaat ggaactggga ctaacaccta tgcggcctta      300

aacagtgtct atctcatgat gaacaaccaa atgcgactcc tcggcatgga aacgatggcc      360

tggcaggaaa tccgacatgc catcatcctt ctgacagatg gaaagtccaa tatgggtggc      420

tctcccaaga cagctgttga ccatatcaga gagatcctga acatcaacca gaagaggaat      480

gactatctgg acatctatgc catcggggtg ggcaagctgg atgtggactg gagagaactg      540

aatgagctag ggtccaagaa ggatggtgag aggcatgcct tcattctgca ggacacaaag      600

gctctgcacc aggtctttga acatatgctg gatgtctcca agctcacaga caccatctgc      660

ggggtgggga acatgtcagc aaacgcctct gaccaggaga ggacaccctg gcatgtcact      720

attaagccca agagccaaga gacctgccgg ggggccctca tctccgacca atgggtcctg      780

acagcagctc attgcttccg cgatggcaac gaccactccc tgtggagggt caatgtggga      840

gaccccaaat cccagtgggg caaagaattc cttattgaga aggcggtgat ctccccaggg      900

tttgatgtct ttgccaaaaa gaaccaggga atcctggagt tctatggtga tgacatagct      960

ctgctgaagc tggcccagaa agtaaagatg tccacccatg ccaggcccat ctgccttccc     1020

tgcacgatgg aggccaatct ggctctgcgg agacctcaag gcagcacctg tagggaccat     1080

gagaatgaac tgctgaacaa acagagtgtt cctgctcatt ttgtcgcctt gaatgggagc     1140

aaactgaaca ttaaccttaa gatgggagtg gagtggacaa gctgtgccga ggttgtctcc     1200

caagaaaaaa ccatgttccc caacttgaca gatgtcaggg aggtggtgac agaccagttc     1260

ctatgcagtg ggacccagga ggatgagagt ccctgcaagg gagaatctgg gggagcagtt     1320

ttccttgagc ggagattcag gttttttcag gtgggtctgg tgagctgggg tctttacaac     1380

ccctgccttg gctctgctga caaaaactcc cgcaaaaggg cccctcgtag caaggtcccg     1440

ccgccacgag actttcacat caatctcttc cgcatgcagc cctggctgag gcagcacctg     1500

ggggatgtcc tgaatttttt acccctc                                         1527


<210>  5096
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  5096
atgacttgca aaatgtcgca gctggaacgc aacatagaga ccatcatcaa caccttccac       60

caatactctg tgaagctggg gcacccagac accctgaacc agggggaatt caaagagctg      120

gtgcgaaaag atctgcaaaa ttttctcaag aaggagaata agaatgaaaa ggtcatagaa      180

cacatcatgg aggacctgga cacaaatgca gacaagcagc tgagcttcga ggagttcatc      240

atgctgatgg cgaggctaac ctgggcctcc cacgagaaga tgcacgaggg tgacgagggc      300

cctggccacc accataagcc aggcctcggg gagggcaccc cc                         342


<210>  5097
<211>  1344
<212>  DNA
<213>  Homo Sapiens

<400>  5097
gccgaccaaa gaagagattt tatcgacatc gaaagtaaat ttgccctaag gacccctgaa       60

gacacagctg aggacacttg ccacctcatt cccggagtag cagagtccgt ggctacctgt      120

catttcaatc acagcagcaa aaccttcatg gtgatccatg gctggacggt aacaggaatg      180

tatgagagtt gggtgccaaa acttgtggcc gccctgtaca agagagaacc agactccaat      240

gtcattgtgg tggactggct gtcacgggct caggagcatt acccagtgtc cgcgggctac      300

accaaactgg tgggacagga tgtggcccgg tttatcaact ggatggagga ggagtttaac      360

taccctctgg acaatgtcca tctcttggga tacagccttg gagcccatgc tgctggcatt      420

gcaggaagtc tgaccaataa gaaagtcaac agaattactg gcctcgatcc agctggacct      480

aactttgagt atgcagaagc cccgagtcgt ctttctcctg atgatgcaga ttttgtagac      540

gtcttacaca cattcaccag agggtcccct ggtcgaagca ttggaatcca gaaaccagtt      600

gggcatgttg acatttaccc gaatggaggt acttttcagc caggatgtaa cattggagaa      660

gctatccgcg tgattgcaga gagaggactt ggagatgtgg accagctagt gaagtgctcc      720

cacgagcgct ccattcatct cttcatcgac tctctgttga atgaagaaaa tccaagtaag      780

gcctacaggt gcagttccaa ggaagccttt gagaaagggc tctgcttgag ttgtagaaag      840

aaccgctgca acaatctggg ctatgagatc agtaaagtca gagccaaaag aagcagcaaa      900

atgtacctga agactcgttc tcagatgccc tacaaagtct tccattacca agtaaagatt      960

catttttctg ggactgagag tgaaacccat accaatcagg cctttgagat ttctctgtat     1020

ggcaccgtgg ccgagagtga gaacatccca ttcactctgc ctgaagtttc cacaaataag     1080

acctactcct tcctaattta cacagaggta gatattggag aactactcat gttgaagctc     1140

aaatggaaga gtgattcata ctttagctgg tcagactggt ggagcagtcc cggcttcgcc     1200

attcagaaga tcagagtaaa agcaggagag actcagaaaa aggtgatctt ctgttctagg     1260

gagaaagtgt ctcatttgca gaaaggaaag gcacctgcgg tatttgtgaa atgccatgac     1320

aagtctctga ataagaagtc aggc                                            1344


<210>  5098
<211>  1323
<212>  DNA
<213>  Homo Sapiens

<400>  5098
acactggaga agaatgtgtt ggttgtctct gtagtcacac ctggatgtaa ccagcttcct       60

actttggagt cagtggagaa ttataccctg accataaatg atgaccagtg tttactcctc      120

tctgagactg tctggggagc tctccgaggt ctggagactt ttagccagct tgtttggaaa      180

tctgctgagg gcacattctt tatcaacaag actgagattg aggactttcc ccgctttcct      240

caccggggct tgctgttgga tacatctcgc cattacctgc cactctctag catcctggac      300

actctggatg tcatggcgta caataaattg aacgtgttcc actggcatct ggtagatgat      360

ccttccttcc catatgagag cttcactttt ccagagctca tgagaaaggg gtcctacaac      420

cctgtcaccc acatctacac agcacaggat gtgaaggagg tcattgaata cgcacggctc      480

cggggtatcc gtgtgcttgc agagtttgac actcctggcc acactttgtc ctggggacca      540

ggtatccctg gattactgac tccttgctac tctgggtctg agccctctgg cacctttgga      600

ccagtgaatc ccagtctcaa taatacctat gagttcatga gcacattctt cttagaagtc      660

agctctgtct tcccagattt ttatcttcat cttggaggag atgaggttga tttcacctgc      720

tggaagtcca acccagagat ccaggacttt atgaggaaga aaggcttcgg tgaggacttc      780

aagcagctgg agtccttcta catccagacg ctgctggaca tcgtctcttc ttatggcaag      840

ggctatgtgg tgtggcagga ggtgtttgat aataaagtaa agattcagcc agacacaatc      900

atacaggtgt ggcgagagga tattccagtg aactatatga aggagctgga actggtcacc      960

aaggccggct tccgggccct tctctctgcc ccctggtacc tgaaccgtat atcctatggc     1020

cctgactgga aggatttcta cgtagtggaa cccctggcat ttgaaggtac ccctgagcag     1080

aaggctctgg tgattggtgg agaggcttgt atgtggggag aatatgtgga caacacaaac     1140

ctggtcccca ggctctggcc cagagcaggg gctgttgccg aaaggctgtg gagcaacaag     1200

ttgacatctg acctgacatt tgcctatgaa cgtttgtcac acttccgctg tgagttgctg     1260

aggcgaggtg tccaggccca acccctcaat gtaggcttct gtgagcagga gtttgaacag     1320

acc                                                                   1323


<210>  5099
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  5099
attgtgggag gctgggagtg tgagcagcat tcccagccct ggcaggcggc tctgtaccat       60

ttcagcactt tccagtgtgg gggcatcctg gtgcaccgcc agtgggtgct cacagctgct      120

cattgcatca gcgacaatta ccagctctgg ctgggtcgcc acaacttgtt tgacgacgaa      180

aacacagccc agtttgttca tgtcagtgag agcttcccac accctggctt caacatgagc      240

ctcctggaga accacacccg ccaagcagac gaggactaca gccacgacct catgctgctc      300

cgcctgacag agcctgctga taccatcaca gacgctgtga aggtcgtgga gttgcccacc      360

caggaacccg aagtggggag cacctgtttg gcttccggct ggggcagcat cgaaccagag      420

aatttctcat ttccagatga tctccagtgt gtggacctca aaatcctgcc taatgatgag      480

tgcaaaaaag tccacgtcca gaaggtgaca gacttcatgc tgtgtgtcgg acacctggaa      540

ggtggcaaag acacctgtgt gggtgattca gggggcccgc tgatgtgtga tggtgtgctc      600

caaggtgtca catcatgggg ctacgtccct tgtggcaccc ccaataagcc ttctgtcgcc      660

gtcagagtgc tgtcttatgt gaagtggatc gaggacacca tagcggagaa ctcc            714


<210>  5100
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5100
tcccacttca atcctctgtc tctcgaggaa ctaggctcca acacggggat ccaggttttc       60

aatcagattg tgaagtcgag gcctcatgac aacatcgtga tctctcccca tgggattgcg      120

tcggtcctgg ggatgcttca gctgggggcg gacggcagga ccaagaagca gctcgccatg      180

gtgatgagat acggcgtaaa tggagttggt aaaatattaa agaagatcaa caaggccatc      240

gtctccaaga agaataaaga cattgtgaca gtggctaacg ccgtgtttgt taagaatgcc      300

tctgaaattg aagtgccttt tgttacaagg aacaaagatg tgttccagtg tgaggtccgg      360

aatgtgaact ttgaggatcc agcctctgcc tgtgattcca tcaatgcatg ggttaaaaat      420

gaaaccaggg atatgattga caatctgctg tccccagatc ttattgatgg tgtgctcacc      480

agactggtcc tcgtcaacgc agtgtatttc aagggtctgt ggaaatcacg gttccaaccc      540

gagaacacaa agaaacgcac tttcgtggca gccgacggga aatcctatca agtgccaatg      600

ctggcccagc tctccgtgtt ccggtgtggg tcgacaagtg cccccaatga tttatggtac      660

aacttcattg aactgcccta ccacggggaa agcatcagca tgctgattgc actgccgact      720

gagagctcca ctccgctgtc tgccatcatc ccacacatca gcaccaagac catagacagc      780

tggatgagca tcatggtgcc caagagggtg caggtgatcc tgcccaagtt cacagctgta      840

gcacaaacag atttgaagga gccgctgaaa gttcttggca ttactgacat gtttgattca      900

tcaaaggcaa attttgcaaa aataacaagg tcagaaaacc tccatgtttc tcatatcttg      960

caaaaagcaa aaattgaagt cagtgaagat ggaaccaaag cttcagcagc aacaactgca     1020

attctcattg caagatcatc gcctccctgg tttatagtag acagaccttt tctgtttttc     1080

atccgacata atcctacagg tgctgtgtta ttcatggggc agataaacaa accc           1134


<210>  5101
<211>  1137
<212>  DNA
<213>  Homo Sapiens

<400>  5101
ttgtttggaa aattacatcc tggaagccct gaagtgacta tgaacattag tcagatgatt       60

acttattggg gatacccaaa tgaagaatat gaagttgtga ctgaagatgg ttatattctt      120

gaagtcaata gaattcctta tgggaagaaa aattcaggga atacaggcca gagacctgtt      180

gtgtttttgc agcatggttt gcttgcatca gccacaaact ggatttccaa cctgccgaac      240

aacagccttg ccttcattct ggcagatgct ggttatgatg tgtggctggg caacagcaga      300

ggaaacacct gggccagaag aaacttgtac tattcaccag attcagttga attctgggct      360

ttcagctttg atgaaatggc taaatatgac cttccagcca caatcgactt cattgtaaag      420

aaagctggac agaagcagct acactatgtt ggccattccc agggcaccac cattggtttt      480

attgcctttt ccaccaatcc cagcctggct aaaagaatca aaaccttcta tgctctagct      540

cctgttgcca ctgtgaagta tacaaaaagc cttataaaca aacttagatt tgttcctcaa      600

tccctcttca agtttatatt tggtgacaaa atattctacc cacacaactt ctttgatcaa      660

tttcttgcta ctgaagtgtg ctcccgtgag atgctgaatc tcctttgcag caatgcctta      720

tttataattt gtggatttga cagtaagaac tttaacacga gtcgcttgga tgtgtatcta      780

tcacataatc cagcaggaac ttctgttcaa aacatgttcc attggaccca ggctgttaag      840

tctgggaaat tccaagctta tgactgggga agcccagttc agaataggat gcactatgat      900

cagtcccagc ctccctacta caatgtgaca gccatgaatg taccaattgc agtgtggaac      960

ggtggcaagg acctgttggc tgacccccaa gatgttggcc ttttgcttcc aaaactcccc     1020

aatcttattt accacaagga gattcctttt tacaatcact tggactttat ctgggcaatg     1080

gatgcccctc aagaagttta caatgacatt gtttctatga tatcagaaga taaaaag        1137


<210>  5102
<211>  1473
<212>  DNA
<213>  Homo Sapiens

<400>  5102
gacgcccccg aggaggagga ccacgtcctg gtgctgcgga aaagcaactt cgcggaggcg       60

ctggcggccc acaagtacct gctggtggag ttctatgccc cttggtgtgg ccactgcaag      120

gctctggccc ctgagtatgc caaagccgct gggaagctga aggcagaagg ttccgagatc      180

aggttggcca aggtggacgc cacggaggag tctgacctgg cccagcagta cggcgtgcgc      240

ggctatccca ccatcaagtt cttcaggaat ggagacacgg cttcccccaa ggaatataca      300

gctggcagag aggctgatga catcgtgaac tggctgaaga agcgcacggg cccggctgcc      360

accaccctgc ctgacggcgc agctgcagag tccttggtgg agtccagcga ggtggctgtc      420

atcggcttct tcaaggacgt ggagtcggac tctgccaagc agtttttgca ggcagcagag      480

gccatcgatg acataccatt tgggatcact tccaacagtg acgtgttctc caaataccag      540

ctcgacaaag atggggttgt cctctttaag aagtttgatg aaggccggaa caactttgaa      600

ggggaggtca ccaaggagaa cctgctggac tttatcaaac acaaccagct gccccttgtc      660

atcgagttca ccgagcagac agccccgaag atttttggag gtgaaatcaa gactcacatc      720

ctgctgttct tgcccaagag tgtgtctgac tatgacggca aactgagcaa cttcaaaaca      780

gcagccgaga gcttcaaggg caagatcctg ttcatcttca tcgacagcga ccacaccgac      840

aaccagcgca tcctcgagtt ctttggcctg aagaaggaag agtgcccggc cgtgcgcctc      900

atcaccctgg aggaggagat gaccaagtac aagcccgaat cggaggagct gacggcagag      960

aggatcacag agttctgcca ccgcttcctg gagggcaaaa tcaagcccca cctgatgagc     1020

caggagctgc cggaggactg ggacaagcag cctgtcaagg tgcttgttgg gaagaacttt     1080

gaagacgtgg cttttgatga gaaaaaaaac gtctttgtgg agttctatgc cccatggtgt     1140

ggtcactgca aacagttggc tcccatttgg gataaactgg gagagacgta caaggaccat     1200

gagaacatcg tcatcgccaa gatggactcg actgccaacg aggtggaggc cgtcaaagtg     1260

cacagcttcc ccacactcaa gttctttcct gccagtgccg acaggacggt cattgattac     1320

aacggggaac gcacgctgga tggttttaag aaattcctgg agagcggtgg ccaggatggg     1380

gcaggggatg atgacgatct cgaggacctg gaagaagcag aggagccaga catggaggaa     1440

gacgatgatc agaaagctgt gaaagatgaa ctg                                  1473


<210>  5103
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  5103
attgtgggag gctgggagtg cgagaagcat tcccaaccct ggcaggtgct tgtggcctct       60

cgtggcaggg cagtctgcgg cggtgttctg gtgcaccccc agtgggtcct cacagctgcc      120

cactgcatca ggaacaaaag cgtgatcttg ctgggtcggc acagcttgtt tcatcctgaa      180

gacacaggcc aggtatttca ggtcagccac agcttcccac acccgctcta cgatatgagc      240

ctcctgaaga atcgattcct caggccaggt gatgactcca gccacgacct catgctgctc      300

cgcctgtcag agcctgccga gctcacggat gctgtgaagg tcatggacct gcccacccag      360

gagccagcac tggggaccac ctgctacgcc tcaggctggg gcagcattga accagaggag      420

ttcttgaccc caaagaaact tcagtgtgtg gacctccatg ttatttccaa tgacgtgtgt      480

gcgcaagttc accctcagaa ggtgaccaag ttcatgctgt gtgctggacg ctggacaggg      540

ggcaaaagca cctgctcggg tgattctggg ggcccacttg tctgtaatgg tgtgcttcaa      600

ggtatcacgt catggggcag tgaaccatgt gccctgcccg aaaggccttc cctgtacacc      660

aaggtggtgc attaccggaa gtggatcaag gacaccatcg tggccaaccc c               711


<210>  5104
<211>  1044
<212>  DNA
<213>  Homo Sapiens

<400>  5104
gggcccattc ccgaggtgct caagaactac atggacgccc agtactacgg ggagattggc       60

atcgggacgc ccccccagtg cttcacagtc gtcttcgaca cgggctcctc caacctgtgg      120

gtcccctcca tccactgcaa actgctggac atcgcttgct ggatccacca caagtacaac      180

agcgacaagt ccagcaccta cgtgaagaat ggtacctcgt ttgacatcca ctatggctcg      240

ggcagcctct ccgggtacct gagccaggac actgtgtcgg tgccctgcca gtcagcgtcg      300

tcagcctctg ccctgggcgg tgtcaaagtg gagaggcagg tctttgggga ggccaccaag      360

cagccaggca tcaccttcat cgcagccaag ttcgatggca tcctgggcat ggcctacccc      420

cgcatctccg tcaacaacgt gctgcccgtc ttcgacaacc tgatgcagca gaagctggtg      480

gaccagaaca tcttctcctt ctacctgagc agggacccag atgcgcagcc tgggggtgag      540

ctgatgctgg gtggcacaga ctccaagtat tacaagggtt ctctgtccta cctgaatgtc      600

acccgcaagg cctactggca ggtccacctg gaccaggtgg aggtggccag cgggctgacc      660

ctgtgcaagg agggctgtga ggccattgtg gacacaggca cttccctcat ggtgggcccg      720

gtggatgagg tgcgcgagct gcagaaggcc atcggggccg tgccgctgat tcagggcgag      780

tacatgatcc cctgtgagaa ggtgtccacc ctgcccgcga tcacactgaa gctgggaggc      840

aaaggctaca agctgtcccc agaggactac acgctcaagg tgtcgcaggc cgggaagacc      900

ctctgcctga gcggcttcat gggcatggac atcccgccac ccagcgggcc actctggatc      960

ctgggcgacg tcttcatcgg ccgctactac actgtgtttg accgtgacaa caacagggtg     1020

ggcttcgccg aggctgcccg cctc                                            1044


<210>  5105
<211>  1014
<212>  DNA
<213>  Homo Sapiens

<400>  5105
tctactgttc acgaaatcct gtgcaagctc agcttggagg gtgatcactc tacaccccca       60

agtgcatatg ggtctgtcaa agcctatact aactttgatg ctgagcggga tgctttgaac      120

attgaaacag ccatcaagac caaaggtgtg gatgaggtca ccattgtcaa cattttgacc      180

aaccgcagca atgcacagag acaggatatt gccttcgcct accagagaag gaccaaaaag      240

gaacttgcat cagcactgaa gtcagcctta tctggccacc tggagacggt gattttgggc      300

ttattgaaga cacctgctca gtatgacgct tctgagctaa aagcttccat gaaggggctg      360

ggaaccgacg aggactctct cattgagatc atctgctcca gaaccaacca ggagctgcag      420

gaaattaaca gagtctacaa ggaaatgtac aagactgatc tggagaagga cattatttcg      480

gacacatctg gtgacttccg caagctgatg gttgccctgg caaagggtag aagagcagag      540

gatggctctg tcattgatta tgaactgatt gaccaagatg ctcgggatct ctatgacgct      600

ggagtgaaga ggaaaggaac tgatgttccc aagtggatca gcatcatgac cgagcggagc      660

gtgccccacc tccagaaagt atttgatagg tacaagagtt acagccctta tgacatgttg      720

gaaagcatca ggaaagaggt taaaggagac ctggaaaatg ctttcctgaa cctggttcag      780

tgcattcaga acaagcccct gtattttgct gatcggctgt atgactccat gaagggcaag      840

gggacgcgag ataaggtcct gatcagaatc atggtctccc gcagtgaagt ggacatgttg      900

aaaattaggt ctgaattcaa gagaaagtac ggcaagtccc tgtactatta tatccagcaa      960

gacactaagg gcgactacca gaaagcgctg ctgtacctgt gtggtggaga tgac           1014


<210>  5106
<211>  546
<212>  DNA
<213>  Homo Sapiens

<400>  5106
cagaagcctc agaggccacg ccggcccgca tcccccatca gcaccatcca gcccaaggcc       60

aattttgatg cgcagcagtt tgcagggacc tggctccttg tggctgtggg ctccgcttgc      120

cgtttcctgc aggagcaggg ccaccgggcc gaggccacca cactgcatgt ggctccccag      180

ggcacagcca tggctgtcag taccttccga aagctggatg ggatctgctg gcaggtgcgc      240

cagctctatg gagacacagg ggtcctcggc cgcttcctgc ttcaagcccg aggcgcccga      300

ggggctgtgc acgtggttgt cgctgagacc gactaccaga gtttcgctgt cctgtacctg      360

gagcgggcgg ggcagctgtc agtgaagctc tacgcccgct cgctccctgt gagcgactcg      420

gtcctgagtg ggtttgagca gcgggtccag gaggcccacc tgactgagga ccagatcttc      480

tacttcccca agtacggctt ctgcgaggct gcagaccagt tccacgtcct ggacgaagtg      540

aggagg                                                                 546


<210>  5107
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5107
atcgttgggg gctacaactg tgaggagaat tctgtcccct accaggtgtc cctgaattct       60

ggctaccact tctgtggtgg ctccctcatc aacgaacagt gggtggtatc agcaggccac      120

tgctacaagt cccgcatcca ggtgagactg ggagagcaca acatcgaagt cctggagggg      180

aatgagcagt tcatcaatgc agccaagatc atccgccacc cccaatacga caggaagact      240

ctgaacaatg acatcatgtt aatcaagctc tcctcacgtg cagtaatcaa cgcccgcgtg      300

tccaccatct ctctgcccac cgcccctcca gccactggca cgaagtgcct catctctggc      360

tggggcaaca ctgcgagctc tggcgccgac tacccagacg agctgcagtg cctggatgct      420

cctgtgctga gccaggctaa gtgtgaagcc tcctaccctg gaaagattac cagcaacatg      480

ttctgtgtgg gcttccttga gggaggcaag gattcatgtc agggtgattc tggtggccct      540

gtggtctgca atggacagct ccaaggagtt gtctcctggg gtgatggctg tgcccagaag      600

aacaagcctg gagtctacac caaggtctac aactatgtga aatggattaa gaacaccata      660

gctgccaata gc                                                          672


<210>  5108
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5108
atcgttgggg gctacatctg tgaggagaat tctgtcccct accaggtgtc cttgaattct       60

ggctaccact tctgcggtgg ctccctcatc agcgaacagt gggtggtgtc agcaggtcac      120

tgctacaagt cccgcatcca ggtgagactg ggagagcaca acatcgaagt cctggagggg      180

aatgaacagt tcatcaatgc agccaagatc atccgccacc ccaaatacaa cagccggact      240

ctggacaatg acatcctgct gatcaagctc tcctcacctg ccgtcatcaa ttcccgcgtg      300

tccgccatct ctctgcccac tgcccctcca gctgctggca ccgagtccct catctccggc      360

tggggcaaca ctctgagttc tggtgccgac tacccagacg agctgcagtg cctggatgct      420

cctgtgctga gccaggctga gtgtgaagcc tcctaccctg gaaagattac caacaacatg      480

ttctgtgtgg gcttcctcga gggaggcaag gattcctgcc agggtgattc tggtggccct      540

gtggtctcca atggagagct ccaaggaatt gtctcctggg gctatggctg tgcccagaag      600

aacaggcctg gagtctacac caaggtctac aactatgtgg actggattaa ggacaccata      660

gctgccaaca gc                                                          672


<210>  5109
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5109
gaggttcaaa accagaaaca accagcatgc catgagaatg atgaaagacc attctatcag       60

aaaacagctc catatgtccc aatgtattat gtgccaaata gctatcctta ttatggaacc      120

aatttgtacc aacgtagacc agctatagca attaataatc catgtgtgcc tcgcacatat      180

tatgcaaacc cagctgtagt taggccacat gcccaaattc ctcagcggca atacctgcca      240

aatagccacc cacccactgt ggtacgtcgc ccaaacctgc atccatcatt tattgccatc      300

cccccaaaga aaattcagga taaaataatc atccctacca tcaataccat tgctactgtt      360

gaacctacac cagctcctgc cactgaacca acggtggaca gtgtagtcac tccagaagct      420

ttttcagagt ccatcatcac gagcacccct gagacaacca cagttgcagt tactccacct      480

acggca                                                                 486


<210>  5110
<211>  249
<212>  DNA
<213>  Homo Sapiens

<400>  5110
tcccttccct gcgacatatg caaagacgtt gtcaccgcag ctggtgatat gctgaaggac       60

aatgccactg aggaggagat ccttgtttac ttggagaaga cctgtgactg gcttccgaaa      120

ccgaacatgt ctgcttcatg caaggagata gtggactcct acctccctgt catcctggac      180

atcattaaag gagaaatgag ccgtcctggg gaggtgtgct ctgctctcaa cctctgcgag      240

tctctccag                                                              249


<210>  5111
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  5111
acccaggttc agcaacttct tgtctcaatc acccttcagt cagagtgtga tgctttcccc       60

aacatatctt cagatgagtc ttatacttta cttgtgaaag aaccagtggc tgtccttaag      120

gccaacagag tttggggagc attacgaggt ttagagacct ttagccagtt agtttatcaa      180

gattcttatg gaactttcac catcaatgaa tccaccatta ttgattctcc aaggttttct      240

cacagaggaa ttttgattga tacatccaga cattatctgc cagttaagat tattcttaaa      300

actctggatg ccatggcttt taataagttt aatgttcttc actggcacat agttgatgac      360

cagtctttcc catatcagag catcactttt cctgagttaa gcaataaagg aagctattct      420

ttgtctcatg tttatacacc aaatgatgtc cgtatggtga ttgaatatgc cagattacga      480

ggaattcgag tcctgccaga atttgatacc cctgggcata cactatcttg gggaaaaggt      540

cagaaagacc tcctgactcc atgttacagt agacaaaaca agttggactc ttttggacct      600

ataaacccta ctctgaatac aacatacagc ttccttacta catttttcaa agaaattagt      660

gaggtgtttc cagatcaatt cattcatttg ggaggagatg aagtggaatt taaatgttgg      720

gaatcaaatc caaaaattca agatttcatg aggcaaaaag gctttggcac agattttaag      780

aaactagaat ctttctacat tcaaaaggtt ttggatatta ttgcaaccat aaacaaggga      840

tccattgtct ggcaggaggt ttttgatgat aaagcaaagc ttgcgccggg cacaatagtt      900

gaagtatgga aagacagcgc atatcctgag gaactcagta gagtcacagc atctggcttc      960

cctgtaatcc tttctgctcc ttggtactta gatttgatta gctatggaca agattggagg     1020

aaatactata aagtggaacc tcttgatttt ggcggtactc agaaacagaa acaacttttc     1080

attggtggag aagcttgtct atggggagaa tatgtggatg caactaacct cactccaaga     1140

ttatggcctc gggcaagtgc tgttggtgag agactctgga gttccaaaga tgtcagagat     1200

atggatgacg cctatgacag actgacaagg caccgctgca ggatggtcga acgtggaata     1260

gctgcacaac ctctttatgc tggatattgt aaccatgaga acatg                     1305


<210>  5112
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  5112
gcccccagat ctgtggattg gagagagaaa ggctacgtga ctcctgtgaa gaatcagggt       60

cagtgtggtt cttgttgggc ttttagtgct actggtgctc ttgaaggaca gatgttccgg      120

aaaactggga ggcttatctc actgagtgag cagaatctgg tagactgctc tgggcctcaa      180

ggcaatgaag gctgcaatgg tggcctaatg gattatgctt tccagtatgt tcaggataat      240

ggaggcctgg actctgagga atcctatcca tatgaggcaa cagaagaatc ctgtaagtac      300

aatcccaagt attctgttgc taatgacacc ggctttgtgg acatccctaa gcaggagaag      360

gccctgatga aggcagttgc aactgtgggg cccatttctg ttgctattga tgcaggtcat      420

gagtccttcc tgttctataa agaaggcatt tattttgagc cagactgtag cagtgaagac      480

atggatcatg gtgtgctggt ggttggctac ggatttgaaa gcacagaatc agataacaat      540

aaatattggc tggtgaagaa cagctggggt gaagaatggg gcatgggtgg ctacgtaaag      600

atggccaaag accggagaaa ccattgtgga attgcctcag cagccagcta ccccactgtg      660


<210>  5113
<211>  1821
<212>  DNA
<213>  Homo Sapiens

<400>  5113
ctctacttct cgagggatgc ttactgggag aagctgtatg tggaccaggc ggccggcacg       60

cccttgctgt acgtccatgc cctgcgggac gcccctgagg aggtgcccag cttccgcctg      120

ggccagcatc tctacggcac gtaccgcaca cggctgcatg agaacaactg gatctgcatc      180

caggaggaca ccggcctcct ctaccttaac cggagcctgg accatagctc ctgggagaag      240

ctcagtgtcc gcaaccgcgg ctttcccctg ctcaccgtct acctcaaggt cttcctgtca      300

cccacatccc ttcgtgaggg cgagtgccag tggccaggct gtgcccgcgt atacttctcc      360

ttcttcaaca cctcctttcc agcctgcagc tccctcaagc cccgggagct ctgcttccca      420

gagacaaggc cctccttccg cattcgggag aaccgacccc caggcacctt ccaccagttc      480

cgcctgctgc ctgtgcagtt cttgtgcccc aacatcagcg tggcctacag gctcctggag      540

ggtgagggtc tgcccttccg ctgcgccccg gacagcctgg aggtgagcac gcgctgggcc      600

ctggaccgcg agcagcggga gaagtacgag ctggtggccg tgtgcaccgt gcacgccggc      660

gcgcgcgagg aggtggtgat ggtgcccttc ccggtgaccg tgtacgacga ggacgactcg      720

gcgcccacct tccccgcggg cgtcgacacc gccagcgccg tggtggagtt caagcggaag      780

gaggacaccg tggtggccac gctgcgtgtc ttcgatgcag acgtggtacc tgcatcaggg      840

gagctggtga ggcggtacac aagcacgctg ctccccgggg acacctgggc ccagcagacc      900

ttccgggtgg aacactggcc caacgagacc tcggtccagg ccaacggcag cttcgtgcgg      960

gcgaccgtac atgactatag gctggttctc aaccggaacc tctccatctc ggagaaccgc     1020

accatgcagc tggcggtgct ggtcaatgac tcagacttcc agggcccagg agcgggcgtc     1080

ctcttgctcc acttcaacgt gtcggtgctg ccggtcagcc tgcacctgcc cagtacctac     1140

tccctctccg tgagcaggag ggctcgccga tttgcccaga tcgggaaagt ctgtgtggaa     1200

aactgccagg cattcagtgg catcaacgtc cagtacaagc tgcattcctc tggtgccaac     1260

tgcagcacgc taggggtggt cacctcagcc gaggacacct cggggatcct gtttgtgaat     1320

gacaccaagg ccctgcggcg gcccaagtgt gccgaacttc actacatggt ggtggccacc     1380

gaccagcaga cctctaggca ggcccaggcc cagctgcttg taacagtgga ggggtcatat     1440

gtggccgagg aggcgggctg ccccctgtcc tgtgcagtca gcaagagacg gctggagtgt     1500

gaggagtgtg gcggcctggg ctccccaaca ggcaggtgtg agtggaggca aggagatggc     1560

aaagggatca ccaggaactt ctccacctgc tctcccagca ccaagacctg ccccgacggc     1620

cactgcgatg ttgtggagac ccaagacatc aacatttgcc ctcaggactg cctccggggc     1680

agcattgttg ggggacacga gcctggggag ccccggggga ttaaagctgg ctatggcacc     1740

tgcaactgct tccctgagga ggagaagtgc ttctgcgagc ccgaagacat ccaggatcca     1800

ctgtgcgacg agctgtgccg c                                               1821


<210>  5114
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  5114
ttccccattc ctctccccta ttgctggctc tgcagggctc tgatcaagcg gatccaagcc       60

atgattccca agggtgcgct agctgtggca gtggcccagg tgtgccgcgt ggtacctctg      120

gtggcgggcg gcatctgcca gtgcctggct gagcgctact ccgtcatcct gctcgacacg      180

ctgctgggcc gcatgctgcc ccagctggtc tgccgcctcg tcctccggtg ctccatg         237


<210>  5115
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  5115
aaggaatccc gggccaagaa attccagcgg cagcatatgg actcagacag ttcccccagc       60

agcagctcca cctactgtaa ccaaatgatg aggcgccgga atatgacaca ggggcggtgc      120

aaaccagtga acacctttgt gcacgagccc ctggtagatg tccagaatgt ctgtttccag      180

gaaaaggtca cctgcaagaa cgggcagggc aactgctaca agagcaactc cagcatgcac      240

atcacagact gccgcctgac aaacggctcc aggtacccca actgtgcata ccggaccagc      300

ccgaaggaga gacacatcat tgtggcctgt gaagggagcc catatgtgcc agtccacttt      360

gatgcttctg tggaggactc tacc                                             384


<210>  5116
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5116
tcatgctatt tcatacctaa tgagggagtt ccaggagatt caaccaggaa atgcatggat       60

ctcaaaggaa acaaacaccc aataaactcg gagtggcaga ctgacaactg tgagacatgc      120

acttgctacg aaacagaaat ttcatgttgc acccttgttt ctacacctgt gggttatgac      180

aaagacaact gccaaagaat cttcaagaag gaggactgca agtatatcgt ggtggagaag      240

aaggacccaa aaaagacctg ttctgtcagt gaatggataa tc                         282


<210>  5117
<211>  1149
<212>  DNA
<213>  Homo Sapiens

<400>  5117
atggatccta acgctgctta tgtgaacatg agtaaccatc accggggcct ggcttcagcc       60

aacgttgact ttgccttcag cctgtataag cacctagtgg ccttgagtcc caaaaagaac      120

attttcatct cccctgtgag catctccatg gccttagcta tgctgtccct gggcacctgt      180

ggccacacac gggcccagct tctccagggc ctgggtttca acctcactga gaggtctgag      240

actgagatcc accagggttt ccagcacctg caccaactct ttgcaaagtc agacaccagc      300

ttagaaatga ccatgggcaa tgccttgttt cttgatggca gcctggagtt gctggagtca      360

ttctcagcag acatcaagca ctactatgag tcagaggtct tggctatgaa tttccaggac      420

tgggcaacag ccagcagaca gatcaacagc tatgtcaaga ataagacaca ggggaaaatt      480

gtcgacttgt tttcagggct ggatagccca gccatcctcg tcctggtcaa ctatatcttc      540

ttcaaaggca catggacaca gccctttgac ctggcaagca ccagggagga gaacttctat      600

gtggacgaga caactgtggt gaaggtgccc atgatgttgc agtcgagcac catcagttac      660

cttcatgacg cggagctccc ctgccagctg gtgcagatga actacgtggg caatgggact      720

gtcttcttca tccttccgga caaggggaag atgaacacag tcatcgctgc actgagccgg      780

gacacgatta acaggtggtc cgcaggcctg accagcagcc aggtggacct gtacattcca      840

aaggtcacca tctctggagt ctatgacctc ggagatgtgc tggaggaaat gggcattgca      900

gacttgttca ccaaccaggc aaatttctca cgcatcaccc aggacgccca gctgaagtca      960

tcaaaggtgg tccataaagc tgtgctgcaa ctcaatgagg agggtgtgga cacagctggc     1020

tccactgggg tcaccctaaa cctgacgtcc aagcctatca tcttgcgttt caaccagccc     1080

ttcatcatca tgatcttcga ccacttcacc tggagcagcc ttttcctggc gagggttatg     1140

aacccagtg                                                             1149


<210>  5118
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  5118
gtggttggcg gtgaagaagc gaggcccaac agctggccct ggcaggtctc cctgcagtac       60

agctccaatg gcaagtggta ccacacctgc ggagggtccc tgatagccaa cagctgggtc      120

ctgacggctg cccactgcat cagctcctcc aggacctacc gcgtggggct gggccggcac      180

aacctctacg ttgcggagtc cggctcgctg gcagtcagtg tctctaagat tgtggtgcac      240

aaggactgga actccaacca aatctccaaa gggaacgaca ttgccctgct caaactggct      300

aaccccgtct ccctcaccga caagatccag ctggcctgcc tccctcctgc cggcaccatt      360

ctacccaaca actacccctg ctacgtcacg ggctggggaa ggctgcagac caacggggct      420

gttcctgatg tcctgcagca gggccggttg ctggttgtgg actatgccac ctgctccagc      480

tctgcctggt ggggcagcag cgtgaaaacc agtatgatct gtgctggggg tgatggcgtg      540

atctccagct gcaacggaga ctctggcggg ccactgaact gtcaggcgtc tgacggccgg      600

tggcaggtgc acggcatcgt cagcttcggg tctcgcctcg gctgcaacta ctaccacaag      660

ccctccgtct tcacgcgggt ctccaattac atcgactgga tcaattcggt gattgcaaat      720

aac                                                                    723


<210>  5119
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  5119
atgcttggag gtgaagaagc gaggcccaac agctggccct ggcaggtctc cctgcagtac       60

agctccaatg gccagtggta ccacacctgc ggagggtccc tgatagccaa cagctgggtc      120

ctgacggctg cccactgcat cagctcctcc gggatctacc gcgtgatgct gggccagcat      180

aacctctacg ttgcagagtc cggctcgctg gccgtcagtg tctctaagat tgtggtgcac      240

aaggactgga actccgacca ggtctccaaa gggaacgaca ttgccctgct caaactggct      300

aaccccgtct ccctcaccga caagatccag ctggcctgcc tccctcctgc cggcaccatt      360

ctacccaaca actacccctg ctacgtcacg ggctggggaa ggctgcagac caacggggct      420

ctccctgatg acctgaagca gggccggttg ctggttgtgg actatgccac ctgctccagc      480

tctggctggt ggggcagcac cgtgaagacg aatatgatct gtgctggggg tgatggcgtg      540

atatgcacct gcaacggaga ctccggtggg ccgctgaact gtcaggcatc tgacggccgg      600

tgggaggtgc atggcatcgg cagcctcacg tcggtccttg gttgcaacta ctactacaag      660

ccctccatct tcacgcgggt ctccaactac aacgactgga tcaattcggt gattgcaaat      720

aac                                                                    723


<210>  5120
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  5120
attgtggggg gccggcgagc gcggccccac gcgtggccct tcatggtgtc cctgcagctg       60

cgcggaggcc acttctgcgg cgccaccctg attgcgccca acttcgtcat gtcggccgcg      120

cactgcgtgg cgaatgtaaa cgtccgcgcg gtgcgggtgg tcctgggagc ccataacctc      180

tcgcggcggg agcccacccg gcaggtgttc gccgtgcagc gcatcttcga aaacggctac      240

gaccccgtaa acttgctcaa cgacatcgtg attctccagc tcaacgggtc ggccaccatc      300

aacgccaacg tgcaggtggc ccagctgccg gctcagggac gccgcctggg caacggggtg      360

cagtgcctgg ccatgggctg gggccttctg ggcaggaacc gtgggatcgc cagcgtcctg      420

caggagctca acgtgacggt ggtgacgtcc ctctgccgtc gcagcaacgt ctgcactctc      480

gtgaggggcc ggcaggccgg cgtctgtttc ggggactccg gcagcccctt ggtctgcaac      540

gggctaatcc acggaattgc ctccttcgtc cggggaggct gcgcctcagg gctctacccc      600

gatgcctttg ccccggtggc acagtttgta aactggatcg actctatcat ccaacgctcc      660

gaggacaacc cctgtcccca cccccgggac ccggacccgg ccagcaggac ccac            714


<210>  5121
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5121
ttcagaacct ttcctggcat cccgaagtgg aggaaaaccc accttacata caggattgtg       60

aattatacac cagatttgcc aaaagatgct gttgattctg ctgttgagaa agctctgaaa      120

gtctgggaag aggtgactcc actcacattc tccaggctgt atgaaggaga ggctgatata      180

atgatctctt ttgcagttag agaacatgga gacttttacc cttttgatgg acctggaaat      240

gttttggccc atgcctatgc ccctgggcca gggattaatg gagatgccca ctttgatgat      300

gatgaacaat ggacaaagga tacaacaggg accaatttat ttctcgttgc tgctcatgaa      360

attggccact ccctgggtct ctttcactca gccaacactg aagctttgat gtacccactc      420

tatcactcac tcacagacct gactcggttc cgcctgtctc aagatgatat aaatggcatt      480

cagtccctct atggacctcc ccctgactcc cctgagaccc ccctggtacc cacggaacct      540

gtccctccag aacctgggac gccagccaac tgtgatcctg ctttgtcctt tgatgctgtc      600

agcactctga ggggagaaat cctgatcttt aaagacaggc acttttggcg caaatccctc      660

aggaagcttg aacctgaatt gcatttgatc tcttcatttt ggccatctct tccttcaggc      720

gtggatgccg catatgaagt tactagcaag gacctcgttt tcatttttaa aggaaatcaa      780

ttctgggcca tcagaggaaa tgaggtacga gctggatacc caagaggcat ccacacccta      840

ggtttccctc caaccgtgag gaaaatcgat gcagccattt ctgataagga aaagaacaaa      900

acatatttct ttgtagagga caaatactgg agatttgatg agaagagaaa ttccatggag      960

ccaggctttc ccaagcaaat agctgaagac tttccaggga ttgactcaaa gattgatgct     1020

gtttttgaag aatttgggtt cttttatttc tttactggat cttcacagtt ggagtttgac     1080

ccaaatgcaa agaaagtgac acacactttg aagagtaaca gctggcttaa ttgt           1134


<210>  5122
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  5122
tggacgggcg aggactcggc ggagcccaac tctgactcgg cggagtggat ccgagacatg       60

tacgccaagg tcacggagat ctggcaggag gtcatgcagc ggcgggacga cgacggcacg      120

ctccacgccg cctgccaggt gcagccgtcg gccacgctgg acgccgcgca gccccgggtg      180

accggcgtcg tcctcttccg gcagcttgcg ccccgcgcca agctcgacgc cttcttcgcc      240

ctggagggct tcccgaccga gccgaacagc tccagccgcg ccatccacgt gcaccagttc      300

ggggacctga gccagggctg cgagtccacc gggccccact acaacccgct ggccgtgccg      360

cacccgcagc acccgggcga cttcggcaac ttcgcggtcc gcgacggcag cctctggagg      420

taccgcgccg gcctggccgc ctcgctcgcg ggcccgcact ccatcgtggg ccgggccgtg      480

gtcgtccacg ctggcgagga cgacctgggc cgcggcggca accaggccag cgtggagaac      540

gggaacgcgg gccggcggct ggcctgctgc gtggtgggcg tgtgcgggcc cgggctctgg      600

gagcgccagg cgcgggagca ctcagagcgc aagaagcggc ggcgcgagag cgagtgcaag      660

gccgcc                                                                 666


<210>  5123
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  5123
atcatcggag gccgggagag caggccccac tcccgcccct acatggcgta tcttcagatc       60

cagagtccag caggtcagag cagatgtgga gggttcctgg tgcgagaaga ctttgtgctg      120

acagcagctc attgctgggg aagcaatata aatgtcaccc tgggcgccca caatatccag      180

agacgggaaa acacccagca acacatcact gcgcgcagag ccatccgcca ccctcaatat      240

aatcagcgga ccatccagaa tgacatcatg ttattgcagc tgagcagaag agtcagacgg      300

aatcgaaacg tgaacccagt ggctctgcct agagcccagg agggactgag acccgggacg      360

ctgtgcactg tggccggctg gggcagggtc agcatgagga ggggaacaga tacactccga      420

gaggtgcagc tgagagtgca gagggatagg cagtgcctcc gcatcttcgg ttcctacgac      480

ccccgaaggc agatttgtgt gggggaccgg cgggaacgga aggctgcctt caagggggat      540

tccggaggcc ccctgctgtg taacaatgtg gcccacggca tcgtctccta tggaaagtcg      600

tcaggggttc ctccagaagt cttcaccagg gtctcaagtt tcctgccctg gataaggaca      660

acaatgagaa gcttcaaact gctggatcag atggagaccc ccctg                      705


<210>  5124
<211>  2097
<212>  DNA
<213>  Homo Sapiens

<400>  5124
tacgatgatg gtatttgcaa gtcatcagac tgcataaaat cagctgctcg actgatccaa       60

aacatggatg ccaccactga gccttgtaca gactttttca aatatgcttg cggaggctgg      120

ttgaaacgta atgtcattcc cgagaccagc tcccgttacg gcaactttga cattttaaga      180

gatgaactag aagtcgtttt gaaagatgtc cttcaagaac ccaaaactga agatatagta      240

gcagtgcaga aagcaaaagc attgtacagg tcttgtataa atgaatctgc tattgatagc      300

agaggtggag aacctctact caaactgtta ccagacatat atgggtggcc agtagcaaca      360

gaaaactggg agcaaaaata tggtgcttct tggacagctg aaaaagctat tgcacaactg      420

aattctaaat atgggaaaaa agtccttatt aatttgtttg ttggcactga tgataagaat      480

tctgtgaatc atgtaattca tattgaccaa cctcgacttg gcctcccttc tagagattac      540

tatgaatgca ctggaatcta taaagaggct tgtacagcat atgtggattt tatgatttct      600

gtggccagat tgattcgtca ggaagaaaga ttgcccatcg atgaaaacca gcttgctttg      660

gaaatgaata aagttatgga attggaaaaa gaaattgcca atgctacggc taaacctgaa      720

gatcgaaatg atccaatgct tctgtataac aagatgacat tggcccagat ccaaaataac      780

ttttcactag agatcaatgg gaagccattc agctggttga atttcacaaa tgaaatcatg      840

tcaactgtga atattagtat tacaaatgag gaagatgtgg ttgtttatgc tccagaatat      900

ttaaccaaac ttaagcccat tcttaccaaa tattctgcca gagatcttca aaatttaatg      960

tcctggagat tcataatgga tcttgtaagc agcctcagcc gaacctacaa ggagtccaga     1020

aatgctttcc gcaaggccct ttatggtaca acctcagaaa cagcaacttg gagacgttgt     1080

gcaaactatg tcaatgggaa tatggaaaat gctgtgggga ggctttatgt ggaagcagca     1140

tttgctggag agagtaaaca tgtggtcgag gatttgattg cacagatccg agaagttttt     1200

attcagactt tagatgacct cacttggatg gatgccgaga caaaaaagag agctgaagaa     1260

aaggccttag caattaaaga aaggatcggc tatcctgatg acattgtttc aaatgataac     1320

aaactgaata atgagtacct cgagttgaac tacaaagaag atgaatactt cgagaacata     1380

attcaaaatt tgaaattcag ccaaagtaaa caactgaaga agctccgaga aaaggtggac     1440

aaagatgagt ggataagtgg agcagctgta gtcaatgcat tttactcttc aggaagaaat     1500

cagatagtct tcccagccgg cattctgcag ccccccttct ttagtgccca gcagtccaac     1560

tcattgaact atgggggcat cggcatggtc ataggacacg aaatcaccca tggcttcgat     1620

gacaatggca gaaactttaa caaagatgga gacctcgttg actggtggac tcaacagtct     1680

gcaagtaact ttaaggagca atcccagtgc atggtgtatc agtatggaaa cttttcctgg     1740

gacctggcag gtggacagca ccttaatgga attaatacac tgggagaaaa cattgctgat     1800

aatggaggtc ttggtcaagc atacagagcc tatcagaatt atattaaaaa gaatggcgaa     1860

gaaaaattac ttcctggact tgacctaaat cacaaacaac tatttttctt gaactttgca     1920

caggtgtggt gtggaaccta taggccagag tatgcggtta actccattaa aacagatgtg     1980

cacagtccag gcaatttcag gattattggg actttgcaga actctgcaga gttttcagaa     2040

gcctttcact gccgcaagaa ttcatacatg aatccagaaa agaagtgccg ggtttgg        2097


<210>  5125
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  5125
ggcttggagt gtgatggcaa ggtcaacatc tgctgtaaga aacagttctt tgtcagtttc       60

aaggacatcg gctggaatga ctggatcatt gctccctctg gctatcatgc caactactgc      120

gagggtgagt gcccgagcca tatagcaggc acgtccgggt cctcactgtc cttccactca      180

acagtcatca accactaccg catgcggggc catagcccct ttgccaacct caaatcgtgc      240

tgtgtgccca ccaagctgag acccatgtcc atgttgtact atgatgatgg tcaaaacatc      300

atcaaaaagg acattcagaa catgatcgtg gaggagtgtg ggtgctca                   348


<210>  5126
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5126
ggttatcttc tggtaaagca tagccaaacg gaccaggagc ctatgtgtcc ggtaggcatg       60

aataagctgt ggtcgggata cagcctctta tatttcgaag ggcaagagaa ggcacacaat      120

caagacctag ggctggccgg atcttgtttg gcccgtttct caacgatgcc gtttctatat      180

tgcaatccgg gtgacgtatg ctattatgct agtcgaaatg ataaaagtta ttggctgagc      240

accacagcgc ctttgccaat gatgcctgtt gcagaagacg agataaaacc gtacatctca      300

agatgttccg tgtgtgaagc gcctgcaatc gccatagccg tccactcaca ggacgtctca      360

atcccacatt gtccggcggg ctggagaagc ttgtggatag gttacagttt cctcatgcat      420

acagctgcag gggacgaagg aggcggtcaa tcgttagtgt ctcccggttc ctgcctagag      480

gacttcaggg cgacaccatt tattgagtgc aatggaggca gaggaacatg tcactactac      540

gctaataaat attctttctg gttgaccacc attccagagc agagttttca aggttctccc      600

agtgcggata cacttaaagc aggtttgatt cgtactcata tatcacgttg ccaagtctgc      660

atgaaaaacc tc                                                          672


<210>  5127
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  5127
aaccaggagc aggtgtcccc acttaccctc ctcaagttgg gcaaccagga gcctggtggc       60

cagactgccc tgaagagtcc cccaggagtc tgcagcagag accccacccc agagcagacc      120

cacaggctgg cccgggccat gatggccttc actgccgacc tgttctccct ggtggctcaa      180

acgtccacct gccccaacct catcctgtca cccctgagtg tggccctggc gctgtctcac      240

ctggcactag gtgctcagaa ccacacgttg cagaggctgc aacaggtgct gcacgcaggc      300

tcagggccct gcctccccca tctgctgagc cgcctctgcc aggacctggg ccccggcgcg      360

ttccgactgg ctgccaggat gtacctgcag aaaggatttc ccatcaaaga agatttcctg      420

gaacaatccg aacagctatt tggggcaaag cccgtgagcc tgacgggaaa gcaggaagat      480

gacctggcaa acatcaacca atgggtgaag gaggccacgg aggggaagat tcaggaattc      540

ctctctgggc tgccggaaga caccgtgttg cttctcctca acgccatcca cttccagggt      600

ttctggagga acaagtttga cccgagcctt acccagagag actccttcca cctggacgag      660

cagttcacgg tgcccgtgga aatgatgcag gcccgcacgt acccgctgcg ctggttcttg      720

ctggagcagc ctgagatcca ggtggctcat ttccccttta agaacaacat gagctttgtg      780

gtccttgtac ccacccactt tgaatggaac gtgtcccagg tactggccaa cctgagttgg      840

gacaccctgc acccacctct ggtgtgggag aggcccacca aggtccggct gcctaagctg      900

tatctgaaac accaaatgga cctggtggcc accctcagcc agctgggcct gcaggagttg      960

ttccaggccc cagacctgcg tgggatctcc gagcagagcc tggtggtgtc cggcgtgcag     1020

catcagtcca ccctggagct cagcgaggtc ggcgtggagg cggcggcggc caccagcatt     1080

gccatgtccc gcatgtccct gtcctccttc agcgtgaacc gccccttcct cttcttcatc     1140

ttcgaggaca ccacaggcct tcccctcttc gtgggcagcg tgaggaaccc caaccccagt     1200

gcaccgcggg agctcaagga acagcaggat tccccgggca acaaggactt cctccagagc     1260

ctgaaaggct tcccccgcgg agacaagctt ttcggccctg acttaaaact tgtgcccccc     1320

atggaggagg attaccccca gtttggcagc cccaag                               1356


<210>  5128
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5128
gctccgtggc agtgcgcgcc ctgctccgcc gagaagctcg cgctctgccc gccggtgtcc       60

gcctcgtgct cggaggtcac ccggtccgcc ggctgcggct gttgcccgat gtgcgccctg      120

cctctgggcg ccgcgtgcgg cgtggcgact gcacgctgcg cccggggact cagttgccgc      180

gcgctgccgg gggagcagca acctctgcac gccctcaccc gcggccaagg cgcctgcgtg      240

caggagtctg acgcctccgc tccccatgct gcagaggcag ggagccctga aagcccagag      300

agcacggaga taactgagga ggagctcctg gataatttcc atctgatggc cccttctgaa      360

gaggatcatt ccatcctttg ggacgccatc agtacctatg atggctcgaa ggctctccat      420

gtcaccaaca tcaaaaaatg gaaggagccc tgccgaatag aactctacag agtcgtagag      480

agtttagcca aggcacagga gacatcagga gaagaaattt ccaaatttta cctgccaaac      540

tgcaacaaga atggatttta tcacagcaga cagtgtgaga catccatgga tggagaggcg      600

ggactctgct ggtgcgtcta cccttggaat gggaagagga tccctgggtc tccagagatc      660

aggggagacc ccaactgcca gatatatttt aatgtacaaa ac                         702


<210>  5129
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  5129
gttgtcaatg gtgaggatgc ggtcccctac agctggccct ggcaggtttc cctgcagtat       60

gagaaaagtg gaagcttcta ccacacgtgt ggcggtagcc tcatcgcccc cgactgggtt      120

gtgactgccg gccactgcat ctcgagctcc tggacctacc aggtggtgtt gggcgagtac      180

gaccgtgctg tgaaggaggg ccccgagcag gtgatcccca tcaactctgg ggacctcttt      240

gtgcatccac tctggaaccg ctcgtgtgtg gcctgtggca atgacatcgc cctcatcaag      300

ctctcacgca gcgcccagct gggagacgcc gtccagctcg cctcactccc tcccgctggt      360

gacatccttc ccaacgagac accctgctac atcaccggct ggggccgtct ctataccaac      420

gggccactcc cagacaagct gcaggaggcc ctgctgcccg tggtggacta tgaacactgc      480

tccaggtgga actggtgggg ttcctccgtg aagaagacca tggtgtgtgc tggaggggac      540

atccgctccg gctgcaacgg tgactctgga ggacccctca actgccccac agaggatggt      600

ggctggcagg tccatggcgt gaccagcttt gtttctgcct ttggctgcaa cacccgcagg      660

aagcccacgg tgttcactcg agtctccgcc ttcatcgact ggattgagga gaccatagca      720

agccac                                                                 726


<210>  5130
<211>  1185
<212>  DNA
<213>  Homo Sapiens

<400>  5130
cggtgtttga acctgaagag ccccacagcc ccacctgacc tctacttcca ggactcgggg       60

ctctcacgct ttctgctcaa gtcctgtcct cttctgacca aagaatacat tccaccgttg      120

atctggggga aaagtggaca catccagaca gccttgtatg ggaagatggg aagggtgagg      180

tcgccacatc cttatgggca ccggaagttc atcactatgt ctgatggagc cacttctaca      240

ttcgacctct tcgagccctt ggctgagcac tgtgttggag atgatatcac catggtcatc      300

tgccctggaa ttgccaatca cagcgagaag caatacatcc gcactttcgt tgactacgcc      360

cagaaaaatg gctatcggtg cgccgtgctg aaccacctgg gtgccctgcc caacattgaa      420

ttgacctcgc cacgcatgtt cacctatggc tgcacgtggg aatttggagc catggtgaac      480

tacatcaaga agacatatcc cctgacccag ctggtcgtcg tgggcttcag cctgggtggt      540

aacattgtgt gcaaatactt gggggagact caggcaaacc aagagaaggt cctgtgctgc      600

gtcagcgtgt gccaggggta cagtgcactg agggcccagg aaaccttcat gcaatgggat      660

cagtgccagc ggttctacaa cttcctcatg gctgacaaca tgaagaagat catcctctcg      720

cacaggcaag ctctttttgg agaccatgtt aagaaacccc agagcctgga agacacggac      780

ttgagccggc tctacacagc aacatccctg atgcagattg atgacaatgt gatgaggaag      840

tttcacggct ataactccct gaaggaatac tatgaggaag aaagttgcat gcggtacctg      900

cacaggattt atgttcctct catgctggtt aatgcagctg acgatccgtt ggtgcatgaa      960

agtcttctaa ccattccaaa atctctttca gagaaacgag agaacgtcat gtttgtgctg     1020

cctctgcatg ggggccactt gggcttcttt gagggctctg tgctgttccc cgagcccctg     1080

acatggatgg ataagctggt ggtggagtac gccaacgcca tttgccaatg ggagcgtaac     1140

aagttgcagt gctctgacac ggagcaggtg gaggccgacc tggag                     1185


<210>  5131
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  5131
gttgtccatg gtgaggatgc ggtcccctac agctggccct ggcaggtttc cctgcagtat       60

gagaaaagtg gaagcttcta ccacacgtgt ggcggtagcc tcatcgcccc cgattgggtt      120

gtgactgccg gccactgcat ctcgagggat ctgacctacc aggtggtgtt gggtgagtac      180

aaccttgctg tgaaggaggg ccccgagcag gtgatcccca tcaactctga ggagctgttt      240

gtgcatccac tctggaaccg ctcgtgtgtg gcctgtggca atgacatcgc cctcatcaag      300

ctctcacgca gcgcccagct gggagatgcc gtccagctcg cctcactccc tcccgctggt      360

gacatccttc ccaacaagac accctgctac atcaccggct ggggccgtct ctataccaat      420

gggccactcc cagacaagct gcagcaggcc cggctgcccg tggtggacta taagcactgc      480

tccaggtgga actggtgggg ttccaccgtg aagaaaacca tggtgtgtgc tggagggtac      540

atccgctccg gctgcaacgg tgactctgga ggacccctca actgccccac agaggatggt      600

ggctggcagg tccacggtgt gaccagcttt gtttctggct ttggctgcaa cttcatctgg      660

aagcctacag tgttcactcg agtctccgcc ttcatcgact ggattgagga gaccatagca      720

agccac                                                                 726


<210>  5132
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  5132
tggagccccc aggaggagga caggataatc gagggtggca tctatgatgc agacctcaat       60

gatgagcggg tacagcgtgc ccttcacttt gtcatcagcg agtataacaa ggccactgaa      120

gatgagtact acagacgcct gctgcgggtg ctacgagcca gggagcagat cgtgggcggg      180

gtgaattact tcttcgacat agaggtgggc cgaaccatat gtaccaagtc ccagcccaac      240

ttggacacct gtgccttcca tgaacagcca gaactgcaga agaaacagtt gtgctctttc      300

cagatctacg aagttccctg ggaggacaga atgtccctgg tgaattccag gtgtcaagaa      360

gcc                                                                    363


<210>  5133
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  5133
tactcactat ttccaaatag cccaaaatgg acttccaaag tggtcaccta caggatcgta       60

tcatatactc gagacttacc gcatattaca gtggatcgat tagtgtcaaa ggctttaaac      120

atgtggggca aagagatccc cctgcatttc aggaaagttg tatggggaac tgctgacatc      180

atgattggct ttgcgcgagg agctcatggg gactcctacc catttgatgg gccaggaaac      240

acgctggctc atgcctttgc gcctgggaca ggtctcggag gagatgctca cttcgatgag      300

gatgaacgct ggacggatgg tagcagtcta gggattaact tcctgtatgc tgcaactcat      360

gaacttggcc attctttggg tatgggacat tcctctgatc ctaatgcagt gatgtatcca      420

acctatggaa atggagatcc ccaaaatttt aaactttccc aggatgatat taaaggcatt      480

cagaaactat atggaaagag aagtaattca agaaagaaa                             519


<210>  5134
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5134
ttcagctcct ttcctggcat gccgaagtgg aggaaaaccc accttacata caggattgtg       60

aattatacac cagatttgcc aagagatgct gttgattctg ccattgagaa agctctgaaa      120

gtctgggaag aggtgactcc actcacattc tccaggctgt atgaaggaga ggctgatata      180

atgatctctt ttgcagttaa agaacatgga gacttttact cttttgatgg cccaggacac      240

agtttggctc atgcctaccc acctggacct gggctttatg gagatattca ctttgatgat      300

gatgaaaaat ggacagaaga tgcatcaggc accaatttat tcctcgttgc tgctcatgaa      360

cttggccact ccctggggct ctttcactca gccaacactg aagctttgat gtacccactc      420

tacaactcat tcacagagct cgcccagttc cgcctttcgc aagatgatgt gaatggcatt      480

cagtctctct acggacctcc ccctgcctct actgaggaac ccctggtgcc cacaaaatct      540

gttccttcgg gatctgagat gccagccaag tgtgatcctg ctttgtcctt cgatgccatc      600

agcactctga ggggagaata tctgttcttt aaagacagat atttttggcg aagatcccac      660

tggaaccctg aacctgaatt tcatttgatt tctgcatttt ggccctctct tccatcatat      720

ttggatgctg catatgaagt taacagcagg gacaccgttt ttatttttaa aggaaatgag      780

ttctgggcca tcagaggaaa tgaggtacaa gcaggttatc caagaggcat ccataccctg      840

ggttttcctc caaccataag gaaaattgat gcagctgttt ctgacaagga aaagaagaaa      900

acatacttct ttgcagcgga caaatactgg agatttgatg aaaatagcca gtccatggag      960

caaggcttcc ctagactaat agctgatgac tttccaggag ttgagcctaa ggttgatgct     1020

gtattacagg catttggatt tttctacttc ttcagtggat catcacagtt tgagtttgac     1080

cccaatgcca ggatggtgac acacatatta aagagtaaca gctggttaca ttgc           1134


<210>  5135
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  5135
gcttgtggtc tggtcgccag caacctgaat ctcaaacctg gagagtgcct tcgagtgcga       60

ggcgaggtgg ctcctgacgc taagagcttc gtgctgaacc tgggcaaaga cagcaacaac      120

ctgtgcctgc acttcaaccc tcgcttcaac gcccacggcg acgccaacac catcgtgtgc      180

aacagcaagg acggcggggc ctgggggacc gagcagcggg aggctgtctt tcccttccag      240

cctggaagtg ttgcagaggt gtgcatcacc ttcgaccagg ccaacctgac cgtcaagctg      300

ccagatggat acgaattcaa gttccccaac cgcctcaacc tggaggccat caactacatg      360

gcagctgacg gtgacttcaa gatcaaatgt gtggcctttg ac                         402


<210>  5136
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5136
atggacatcc cccagaccaa gcaggacctg gagctcccaa agttggcagg gacctggcac       60

tccatggcca tggcgaccaa caacatctcc ctcatggcga cactgaaggc ccctctgagg      120

gtccacatca cctcactgtt gcccaccccc gaggacaacc tggagatcgt tctgcacaga      180

tgggagaaca acagctgtgt tgagaagaag gtccttggag agaagactga gaatccaaag      240

aagttcaaga tcaactatac ggtggcgaac gaggccacgc tgctcgatac tgactacgac      300

aatttcctgt ttctctgcct acaggacacc accaccccca tccagagcat gatgtgccag      360

tacctggcca gagtcctggt ggaggacgat gagatcatgc agggattcat cagggctttc      420

aggcccctgc ccaggcacct atggtacttg ctggacttga aacagatgga agagccgtgc      480

cgtttc                                                                 486


<210>  5137
<211>  1005
<212>  DNA
<213>  Homo Sapiens

<400>  5137
tcatggtggt acatgagagc tacaggtggc tcctccaggg tgatgtgcga taatgtgcca       60

ggcctggtga gcagccagcg gcagctgtgt caccgacatc cagatgtgat gcgtgccatt      120

agccagggcg tggccgagtg gacagcagaa tgccagcacc agttccgcca gcaccgctgg      180

aattgcaaca ccctggacag ggatcacagc ctttttggca gggtcctact ccgaagtagt      240

cgggaatctg cctttgttta tgccatctcc tcagctggag ttgtatttgc catcaccagg      300

gcctgtagcc aaggagaagt aaaatcctgt tcctgtgatc caaagaagat gggaagcgcc      360

aaggacagca aaggcatttt tgattggggt ggctgcagtg ataacattga ctatgggatc      420

aaatttgccc gcgcatttgt ggatgcaaag gaaaggaaag gaaaggatgc cagagccctg      480

atgaatcttc acaacaacag agctggcagg aaggctgtaa agcggttctt gaaacaagag      540

tgcaagtgcc acggggtgag cggctcatgt actctcagga catgctggct ggccatggcc      600

gacttcagga aaacgggcga ttatctctgg aggaagtaca atggggccat ccaggtggtc      660

atgaaccagg atggcacagg tttcactgtg gctaacgaga ggtttaagaa gccaacgaaa      720

aatgacctcg tgtattttga gaattctcca gactactgta tcagggaccg agaggcaggc      780

tccctgggta cagcaggccg tgtgtgcaac ctgacttccc ggggcatgga cagctgtgaa      840

gtcatgtgct gtgggagagg ctacgacacc tcccatgtca cccggatgac caagtgtggg      900

tgtaagttcc actggtgctg cgccgtgcgc tgtcaggact gcctggaagc tctggatgtg      960

cacacatgca aggcccccaa gaacgctgac tggacaaccg ctaca                     1005


<210>  5138
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  5138
gagcctcaga attgctcagc caccaaaagt aactaccttc gaggtactgg tccctaccca       60

ccttccgtgg actggcggaa aaaaggaaat tttgtctcac ctgtgaaaaa tcagggtgcc      120

tgcggcagtt gctggacttt ctccaccact ggggccctgg agtctgcaat cgccatcgca      180

accggaaaga tgctgtcctt ggcggaacag cagctggtgg actgcgccca ggacttcaat      240

aatcacggct gccaaggggg tctccccagc caggctttcg agtatatcct gtacaacaag      300

gggatcatgg gtgaagacac ctacccctac cagggcaagg atggttattg caagttccaa      360

cctggaaagg ccatcggctt tgtcaaggat gtagccaaca tcacaatcta tgacgaggaa      420

gcgatggtgg aggctgtggc cctctacaac cctgtgagct ttgcctttga ggtgactcag      480

gacttcatga tgtatagaac gggcatctac tccagtactt cctgccataa aactccagat      540

aaagtaaacc atgcagtact ggctgttggg tatggagaaa aaaatgggat cccttactgg      600

atcgtgaaaa actcttgggg tccccagtgg ggaatgaacg ggtacttcct catcgagcgc      660

ggaaagaaca tgtgtggcct ggctgcctgc gcctcctacc ccatccctct ggtg            714


<210>  5139
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  5139
cacacggccg cgcaggacaa ctgcacgtgt cccaccaaca agatgaccgt gtgcagcccc       60

gacggccccg gcggccgctg ccagtgccgc gcgctgggct cgggcatggc ggtcgactgc      120

tccacgctga cctccaagtg tctgctgctc aaggcgcgca tgagcgcccc caagaacgcc      180

cgcacgctgg tgcggccgag tgagcacgcg ctcgtggaca acgatggcct ctacgacccc      240

gactgcgacc ccgagggccg cttcaaggcg cgccagtgca accagacgtc ggtgtgctgg      300

tgcgtgaact cggtgggcgt gcgccgcacg gacaagggcg acctgagcct acgctgcgat      360

gagctggtgc gcacccacca catcctcatt gacctgcgcc accgccccac cgccggcgcc      420

ttcaaccact cagacctgga cgccgagctg aggcggctct tccgcgagcg ctatcggctg      480

caccccaagt tcgtggcggc cgtgcactac gagcagccca ccatccagat cgagctgcgg      540

cagaacacgt ctcagaaggc cgccggtgac gtggatatcg gcgatgccgc ctactacttc      600

gagagggaca tcaagggcga gtctctattc cagggccgcg gcggcctgga cttgcgcgtg      660

cgcggagaac ccctgcaggt ggagcgcacg ctcatctatt acctggacga gattcccccg      720

aagttctcca tgaagcgcct cacc                                             744


<210>  5140
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  5140
gtcatcccag ctgaggagga gaacccggcc ttctggaacc gccaggcagc tgaggccctg       60

gatgctgcca agaagctgca gcccatccag aaggtcgcca agaacctcat cctcttcctg      120

ggcgatgggt tgggggtgcc cacggtgaca gccaccagga tcctaaaggg gcagaagaat      180

ggcaaactgg ggcctgagac gcccctggcc atggaccgct tcccatacct ggctctgtcc      240

aagacataca atgtggacag acaggtgcca gacagcgcag ccacagccac ggcctacctg      300

tgcggggtca aggccaactt ccagaccatc ggcttgagtg cagccgcccg ctttaaccag      360

tgcaacacga cacgcggcaa tgaggtcatc tccgtgatga accgggccaa gcaagcagga      420

aagtcagtag gagtggtgac caccacacgg gtgcagcacg cctcgccagc cggcacctac      480

gcacacacag tgaaccgcaa ctggtactca gatgctgaca tgcctgcctc agcccgccag      540

gaggggtgcc aggacatcgc cactcagctc atctccaaca tggacattga cgtgatcctt      600

ggcggaggcc gcaagtacat gtttcccatg gggaccccag accctgagta cccagctgat      660

gccagccaga atggaatcag gctggacggg aagaacctgg tgcaggaatg gctggcaaag      720

caccagggtg cctggtatgt gtggaaccgc actgagctca tgcaggcgtc cctggaccag      780

tctgtgaccc atctcatggg cctctttgag cccggagaca cgaaatatga gatccaccga      840

gaccccacac tggacccctc cctgatggag atgacagagg ctgccctgcg cctgctgagc      900

aggaaccccc gcggcttcta cctctttgtg gagggcggcc gcatcgacca tggtcatcat      960

gagggtgtgg cttaccaggc actcactgag gcggtcatgt tcgacgacgc cattgagagg     1020

gcgggccagc tcaccagcga ggaggacacg ctgaccctcg tcaccgctga ccactcccat     1080

gtcttctcct ttggtggcta caccttgcga gggagctcca tcttcgggtt ggcccccagc     1140

aaggctcagg acagcaaagc ctacacgtcc atcctgtacg gcaatggccc gggctacgtg     1200

ttcaactcag gcgtgcgacc agacgtgaat gagagcgaga gcgggagccc cgattaccag     1260

cagcaggcgg cggtgcccct gtcgtccgag acccacggag gcgaagacgt ggcggtgttt     1320

gcgcgcggcc cgcaggcgca cctggtgcat ggtgtgcagg agcagagctt cgtagcgcat     1380

gtcatggcct tcgctgcctg tctggagccc tacacggcct gcgacctggc gcctcccgcc     1440

tgcaccaccg ac                                                         1452


<210>  5141
<211>  1824
<212>  DNA
<213>  Homo Sapiens

<400>  5141
gacgtgtacc aggagcccac agaccccaag tttcctcagc agtggtacct gtctggtgtc       60

actcagcggg acctgaatgt gaaggcggcc tgggcgcagg gctacacagg gcacggcatt      120

gtggtctcca ttctggacga tggcatcgag aagaaccacc cggacttggc aggcaattat      180

gatcctgggg ccagttttga tgtcaatgac caggaccctg acccccagcc tcggtacaca      240

cagatgaatg acaacaggca cggcacacgg tgtgcggggg aagtggctgc ggtggccaac      300

aacggtgtct gtggtgtagg tgtggcctac aacgcccgca ttggaggggt gcgcatgctg      360

gatggcgagg tgacagatgc agtggaggca cgctcgctgg gcctgaaccc caaccacatc      420

cacatctaca gtgccagctg gggccccgag gatgacggca agacagtgga tgggccagcc      480

cgcctcgccg aggaggcctt cttccgtggg gttagccagg gccgaggggg gctgggctcc      540

atctttgtct gggcctcggg gaacgggggc cgggaacatg acagctgcaa ctgcgacggc      600

tacaccaaca gtatctacac gctgtccatc agcagcgcca cgcagtttgg caacgtgccg      660

tggtacagcg aggcctgctc gtccacactg gccacgacct acagcagtgg caaccagaat      720

gagaagcaga tcgtgacgac tgacttgcgg cagaagtgca cggagtctca cacgggcacc      780

tcagcctctg cccccttagc agccggcatc attgctctca ccctggaggc caataagaac      840

ctcacatggc gggacatgca acacctggtg gtacagacct cgaagccagc ccacctcaat      900

gccaacgact gggccaccaa tggtgtgggc cggaaagtga gccactcata tggctacggg      960

cttttggacg caggcgccat ggtggccctg gcccagaatt ggaccacagt ggccccccag     1020

cggaagtgca tcatcgacat cctcaccgag cccaaagaca tcgggaaacg gctcgaggtg     1080

cggaagaccg tgaccgcgtg cctgggcgag cccaaccaca tcactcggct ggagcacgct     1140

caggcgcggc tcaccctgtc ctataatcgc cgtggcgacc tggccatcca cctggtcagc     1200

cccatgggca cccgctccac cctgctggca gccaggccac atgactactc cgcagatggg     1260

tttaatgact gggccttcat gacaactcat tcctgggatg aggatccctc tggcgagtgg     1320

gtcctagaga ttgaaaacac cagcgaagcc aacaactatg ggacgctgac caagttcacc     1380

ctcgtactct atggcaccgc ccctgagggg ctgcccgtac ctccagaaag cagtggctgc     1440

aagaccctca cgtccagtca ggcctgtgtg gtgtgcgagg aaggcttctc cctgcaccag     1500

aagagctgtg tccagcactg ccctccaggc ttcgcccccc aagtcctcga tacgcactat     1560

agcaccgaga atgacgtgga gaccatccgg gccagcgtct gcgccccctg ccacgcctca     1620

tgtgccacat gccaggggcc ggccctgaca gattgcctca gctgccccag ccacgcctcc     1680

ttggaccctg tggagcagac ttgctcccgg caaagccaga gcagccgaga gtccccgcca     1740

cagcagcagc cacctcggct gcccccggag gtggaggcgg ggcaacggct gcgggcaggg     1800

ctgctgccct cacacctgcc tgag                                            1824


<210>  5142
<211>  942
<212>  DNA
<213>  Homo Sapiens

<400>  5142
caggacacct gcaggcaagg gcaccctgga atccctggga accccggtca caatggtctg       60

cctggaagag atggacgaga cggagcgaag ggtgacaaag gcgatgcagg agaaccagga      120

cgtcctggca gcccggggaa ggatgggacg agtggagaga agggagaacg aggagcagat      180

ggaaaagttg aagcaaaagg catcaaaggt gatcaaggct caagaggatc cccaggaaaa      240

catggcccca aggggcttgc agggcccatg ggagagaaag gcctccgagg agagactggg      300

cctcaggggc agaaggggaa taagggtgac gtgggtccca ctggtcctga ggggccaagg      360

ggcaacattg ggcctttggg cccaactggt ttaccgggcc ccatgggccc tattggaaag      420

cctggtccca agggagaagc tggacccacg gggccccagg gtgagccagg agtccgggga      480

ataagaggct ggaaaggaga tcgaggagag aaagggaaaa tcggtgagac tctagtcttg      540

ccaaaaagtg ctttcactgt ggggctcacg gtgctgagca agtttccttc ttcagatgtg      600

cccattaaat ttgataagat cctgtataac gaattcaacc attatgatac agcagcgggg      660

aaattcacgt gccacattgc tggggtctat tacttcacct accacatcac tgttttctcc      720

aggaatgttc aggtgtcttt ggtcaaaaat ggagtaaaaa tactgcacac caaagatgct      780

tacatgagct ctgaggacca ggcctctggc ggcattgtcc tgcagctgaa gctcggggat      840

gaggtgtggc tgcaggtgac aggaggagag aggttcaatg gcttgtttgc tgatgaggac      900

gatgacacaa ctttcacagg gttccttctg ttcagcagcc cg                         942


<210>  5143
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  5143
gtagatgaac agcccctgga gaactacctg gatatggagt acttcggcac tatcggcatc       60

ggaactcctg cccaggattt caccgtcgtc tttgacaccg gctcctccaa cctgtgggtg      120

ccctcagtct actgctccag tcttgcctgc accaaccaca accgcttcaa ccctgaggat      180

tcttccacct accagtccac cagcgagaca gtctccatca cctacggcac cggcagcatg      240

acaggcatcc tcggatacga cactgtccag gttggaggca tctctgacac caatcagatc      300

ttcggcctga gcgagacgga acctggctcc ttcctgtatt atgctccctt cgatggcatc      360

ctggggctgg cctaccccag catttcctcc tccggggcca cacccgtctt tgacaacatc      420

tggaaccagg gcctggtttc tcaggacctc ttctctgtct acctcagcgc cgatgaccag      480

agtggcagcg tggtgatctt tggtggcatt gactcttctt actacactgg aagtctgaac      540

tgggtgcctg ttaccgtcga gggttactgg cagatcaccg tggacagcat caccatgaac      600

ggagaggcca tcgcctgcgc tgagggctgc caggccattg ttgacaccgg cacctctctg      660

ctgaccggcc caaccagccc cattgccaac atccagagcg acatcggagc cagcgagaac      720

tcagatggcg acatggtggt cagctgctca gccatcagca gcctgcccga catcgtcttc      780

accatcaatg gagtccagta ccccgtgcca cccagtgcct acatcctgca gagcgagggg      840

agctgcatca gtggcttcca gggcatgaac ctccccaccg aatctggaga gctttggatc      900

ctgggtgatg tcttcatccg ccagtacttt accgtcttcg acagggcaaa caaccaggtc      960

ggcctggccc ccgtggct                                                    978


<210>  5144
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  5144
gtagatgaac agcccctgga gaactacctg gatatggagt acttcggcac tatcggcatc       60

ggaactcctg cccaggattt cactgtcctc tttgacaccg gctcctccaa cctgtgggtg      120

ccctcagtct actgctccag tcttgcctgc accaaccaca accgcttcaa ccctgaggat      180

tcttccacct accagtccac cagcgagaca gtctccatca cctacggcac cggcagcatg      240

acaggcatcc tcggatacga cactgtccag gttggaggca tctctgacac caatcagatc      300

ttcggcctga gcgagacgga acctggctcc ttcctgtatt atgctccctt cgatggcatc      360

ctggggctgg cctaccccag catttcctcc tccggggcca cacccgtctt tgacaacatc      420

tggaaccagg gcctggtttc tcaggacctc ttctctgtct acctcagcgc cgatgaccag      480

agtggcagcg tggtgatctt tggtggcatt gactcttctt actacactgg aagtctgaac      540

tgggtgcctg ttaccgtcga gggttactgg cagatcaccg tggacagcat caccatgaac      600

ggagaggcca tcgcctgcgc tgagggctgc caggccattg ttgacaccgg cacctctctg      660

ctgaccggcc caaccagccc cattgccaac atccagagcg acatcggagc cagcgagaac      720

tcagatggcg acatggtggt cagctgctca gccatcagca gcctgcccga catcgtcttc      780

accatcaatg gagtccagta ccccgtgcca cccagtgcct acatcctgca gagcgagggc      840

agctgcatca gtggcttcca gggcatgaac ctccccaccg aatctggaga gctttggatc      900

ctgggtgatg tcttcatccg ccagtacttt accgtcttcg acaggacaaa caaccaggtc      960

ggcctggccc ccgtggct                                                    978


<210>  5145
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  5145
cgaagcttct tttcgttcct tggcgaggct tttgatgggg ctcgggacat gtggagagcc       60

tactctgaca tgagagaagc caattacatc ggctcagaca aatacttcca tgctcggggg      120

aactatgatg ctgccaaaag gggacctggg ggtgcctggg ctgcagaagt gatcagcgat      180

gccagagaga atatccagag attctttggc catggtgcgg aggactcgct ggctgatcag      240

gctgccaatg aatggggcag gagtggcaaa gaccccaatc acttccgacc tgctggcctg      300

cctgagaaat ac                                                          312


<210>  5146
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  5146
cgaagcttct tttcgttcct tggcgaggct tttgatgggg ctcgggacat gtggagagcc       60

tactctgaca tgagagaagc caattacatc ggctcagaca aatacttcca tgctcggggg      120

aactatgatg ctgccaaaag gggacctggg ggtgcctggg ccgcagaagt gatcagcaat      180

gccagagaga atatccagag actcacaggc catggtgcgg aggactcgct ggccgatcag      240

gctgccaata aatggggcag gagtggcaga gaccccaatc acttccgacc tgctggcctg      300

cctgagaaat ac                                                          312


<210>  5147
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5147
gtccaaaccg ttccgttatc caggcttttt gaccacgcta tgctccaagc ccatcgcgcg       60

caccagctgg ccattgacac ctaccaggag tttgaagaaa cctatatccc aaaggaccag      120

aagtattcat tcctgcatga ctcccagacc tccttctgct tctcagactc tattccgaca      180

ccctccaaca tggaggaaac gcaacagaaa tccaatctag agctgctccg catctccctg      240

ctgctcatcg agtcgtggct ggagcccgtg cggttcctca ggagtatgtt cgccaacaac      300

ctggtgtatg acacctcgga cagcgatgac tatcacctcc taaaggacct agaggaaggc      360

atccaaacgc tgatggggag gctggaagac ggcagccgcc ggactgggca gatcctcaag      420

cagacctaca gcaagtttga cacaaactcg cacaaccatg acgcactgct caagaactac      480

gggctgctct actgcttcag gaaggacatg gacaaggtcg agacattcct gcgcatggtg      540

cagtgccgct ctgtggaggg cagctgtggc ttc                                   573


<210>  5148
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5148
gtccaaaccg ttcccttatc caggcttttt gaccacgcta tgctccaagc ccatcgcgcg       60

caccagctgg ccattgacac ctaccaggag tttgaagaaa cctatatccc aaaggaccag      120

aagtattcat tcctgcatga ctcccagacc tccttctgct tctcagactc tattccgaca      180

ccctccaaca tggaggaaac gcaacagaaa tccaatctag agctgctccg catctccctg      240

ctgctcatcg agtcgtggct ggagcccgtg cggttcctca ggagtatgtt cgccaacaac      300

ctggtgtatg acacctcgga cagcgatgac tatcacctcc taaaggacct agaggaaggc      360

atccaaacgc tgatggggag gctggaagac ggcagccgcc ggactgggca gatcctcaag      420

cagacctaca gcaagtttga cacaaactcg cacaaccatg acgcactgct caagaactac      480

gggctgctct actgcttcag gaaggacatg gacaaggtcg agacattcct gcgcatggtg      540

cagtgccgct ctgtggaggg cagctgtggc ttc                                   573


<210>  5149
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  5149
gaggacaacg atgagttttt catggacttc ctgcaaacac tactggtggg gaccccagag       60

gagctctatg aggggacctt gggcaagtac aatgtcaacg aagatgccaa ggcagcaatg      120

actgaactca agtcctgcag agatggcctg cagccaatgc acaaggcgga gctggtcaag      180

ctgctggtgc aagtgctggg cagtcaggac ggtgcc                                216


<210>  5150
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  5150
tatcctacgc agagagccag gtaccaatgg gtgcgctgca atccagacag taattctgca       60

aactgccttg aagaaaaagg accaatgttc gaactacttc caggtgaatc caacaagatc      120

ccccgtctga ggactgacct ttttccaaag acgagaatcc aggacttgaa tcgtatcttc      180

ccactttctg aggactactc tggatcaggc ttcggctccg gctccggctc tggatcagga      240

tctgggagtg gcttcctaac ggaaatggaa caggattacc aactagtaga cgaaagtgat      300

gctttccatg acaaccttag gtctcttgac aggaatctgc cctcagacag ccaggacttg      360

ggtcaacatg gattagaaga ggattttatg tta                                   393


<210>  5151
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  5151
atcatcgggg gacatgaggc caagccccac tcccgcccct acatggctta tcttatgatc       60

tgggatcaga agtctctgaa gaggtgcggt ggcttcctga tacaagacga cttcgtgctg      120

acagctgctc actgttgggg aagctccata aatgtcacct tgggggccca caatatcaaa      180

gaacaggagc cgacccagca gtttatccct gtgaaaagac ccatccccca tccagcctat      240

aatcctaaga acttctccaa cgacatcatg ctactgcagc tggagagaaa ggccaagcgg      300

accagagctg tgcagcccct caggctacct agcaacaagg cccaggtgaa gccagggcag      360

acatgcagtg tggccggctg ggggcagacg gcccccctgg gaaaacactc acacacacta      420

caagaggtga agatgacagt gcaggaagat cgaaagtgcg aatctgactt acgccattat      480

tacgacagta ccattgagtt gtgcgtgggg gacccagaga ttaaaaagac ttcctttaag      540

ggggactctg gaggccctct tgtgtgtaac aaggtggccc agggcattgt ctcctatgga      600

cgaaacaatg gcatgcctcc acgagcctgc accaaagtct caagctttgt acactggata      660

aagaaaacca tgaaacgcca c                                                681


<210>  5152
<211>  402
<212>  DNA
<213>  Homo Sapiens

<400>  5152
aaacctccac agtttacctg ggctcaatgg tttgaaaccc agcacatcaa tatgacctcc       60

cagcaatgca ccaatgcaat gcaggtcatt aacaattatc aacggcgatg caaaaaccaa      120

aatactttcc ttcttacaac ttttgctaac gtagttaatg tttgtggtaa cccaaatatg      180

acctgtccta gtaacaaaac tcgcaaaaat tgtcaccaca gtggaagcca ggtgccttta      240

atccactgta acctcacaac tccaagtcca cagaatattt caaactgcag gtatgcgcag      300

acaccagcaa acatgttcta tatagttgca tgtgacaaca gagatcaacg acgagaccct      360

ccacagtatc cggtggttcc agttcacctg gatagaatca tc                         402


<210>  5153
<211>  2649
<212>  DNA
<213>  Homo Sapiens

<400>  5153
gcacaccccg gccgtcccag agcagtgccc acacagtgcg acgtcccccc caacagccgc       60

ttcgattgcg cccctgacaa ggccatcacc caggaacagt gcgaggcccg cggctgttgc      120

tacatccctg caaagcaggg gctgcaggga gcccagatgg ggcagccctg gtgcttcttc      180

ccacccagct accccagcta caagctggag aacctgagct cctctgaaat gggctacacg      240

gccaccctga cccgtaccac ccccaccttc ttccccaagg acatcctgac cctgcggctg      300

gacgtgatga tggagactga gaaccgcctc cacttcacga tcaaagatcc agctaacagg      360

cgctacgagg tgcccttgga gaccccgcat gtccacagcc gggcaccgtc cccactctac      420

agcgtggagt tctccgagga gcccttcggg gtgatcgtgc gccggcagct ggacggccgc      480

gtgctgctga acacgacggt ggcgcccctg ttctttgcgg accagttcct tcagctgtcc      540

acctcgctgc cctcgcagta tatcacaggc ctcgccgagc acctcagtcc cctgatgctc      600

agcaccagct ggaccaggat caccctgtgg aaccgggacc ttgcgcccac gcccggtgcg      660

aacctctacg ggtctcaccc tttctacctg gcgctggagg acggcgggtc ggcacacggg      720

gtgttcctgc taaacagcaa tgccatggat gtggtcctgc agccgagccc tgcccttagc      780

tggaggtcga caggtgggat cctggatgtc tacatcttcc tgggcccaga gcccaagagc      840

gtggtgcagc agtacctgga cgttgtggga tacccgttca tgccgccata ctggggcctg      900

ggcttccacc tgtgccgctg gggctactcc tccaccgcta tcacccgcca ggtggtggag      960

aacatgacca gggcccactt ccccctggac gtccagtgga acgacctgga ctacatggac     1020

tcccggaggg acttcacgtt caacaaggat ggcttccggg acttcccggc catggtgcag     1080

gagctgcacc agggcggccg gcgctacatg atgatcgtgg atcctgccat cagcagctcg     1140

ggccctgccg ggagctacag gccctacgac gagggtctgc ggaggggggt tttcatcacc     1200

aacgagaccg gccagccgct gattgggaag gtatggcccg ggtccactgc cttccccgac     1260

ttcaccaacc ccacagccct ggcctggtgg gaggacatgg tggctgagtt ccatgaccag     1320

gtgcccttcg acggcatgtg gattgacatg aacgagcctt ccaacttcat caggggctct     1380

gaggacggct gccccaacaa tgagctggag aacccaccct acgtgcctgg ggtggttggg     1440

gggaccctcc aggcggccac catctgtgcc tccagccacc agtttctctc cacacactac     1500

aacctgcaca acctctacgg cctgaccgaa gccatcgcct cccacagggc gctggtgaag     1560

gctcggggga cacgcccatt tgtgatctcc cgctcgacct ttgctggcca cggccgatac     1620

gccggccact ggacggggga cgtgtggagc tcctgggagc agctcgcctc ctccgtgcca     1680

gaaatcctgc agtttaacct gctgggggtg cctctggtcg gggccgacgt ctgcggcttc     1740

ctgggcaaca cctcagagga gctgtgtgtg cgctggaccc agctgggggc cttctacccc     1800

ttcatgcgga accacaacag cctgctcagt ctgccccagg agccgtacag cttcagcgag     1860

ccggcccagc aggccatgag gaaggccctc accctgcgct acgcactcct cccccacctc     1920

tacacactgt tccaccaggc ccacgtcgcg ggggagaccg tggcccggcc cctcttcctg     1980

gagttcccca aggactctag cacctggact gtggaccacc agctcctgtg gggggaggcc     2040

ctgctcatca ccccagtgct ccaggccggg aaggccgaag tgactggcta cttccccttg     2100

ggcacatggt acgacctgca gacggtgcca gtagaggccc ttggcagcct cccaccccca     2160

cctgcagctc cccgtgagcc agccatccac agcgaggggc agtgggtgac gctgccggcc     2220

cccctggaca ccatcaacgt ccacctccgg gctgggtaca tcatccccct gcagggccct     2280

ggcctcacaa ccacagagtc ccgccagcag cccatggccc tggctgtggc cctgaccaag     2340

ggtggggagg cccgagggga gcttttctgg gacgatggag agagcctgga agtgctggag     2400

cgaggggcct acacacaggt catcttcctg gccaggaata acacgatcgt gaatgagctg     2460

gtacgtgtga ccagtgaggg agctggcctg cagctgcaga aggtgactgt cctgggcgtg     2520

gccacggcgc cccagcaggt cctctccaac ggtgtccctg tctccaactt cacctacagc     2580

cccgacacca aggtcctgga catctgtgtc tcgctgttga tgggagagca gtttctcgtc     2640

agctggtgt                                                             2649


<210>  5154
<211>  1206
<212>  DNA
<213>  Homo Sapiens

<400>  5154
aaagataacg ccacgtgtga tggcccctgt gggttacggt tcaggcaaaa cccacagggt       60

ggtgtccgca tcgtcggcgg gaaggctgca cagcatgggg cctggccctg gatggtcagc      120

ctccagatct tcacgtacaa cagccacagg taccacacat gtggaggcag cttgctgaat      180

tcacgatggg tgctcactgc tgctcactgc ttcgtcggca aaaataatgt gcatgactgg      240

agactggttt tcggagcaaa ggaaattaca tatgggaaca ataaaccagt aaaggcgcct      300

ctgcaagaga gatatgtgga gaaaatcatc attcatgaaa aatacaactc tgcgacagag      360

ggaaatgaca ttgccctcgt ggagatcacc cctcccattt cgtgtgggcg cttcattggg      420

ccgggctgcc tgccccactt taaggcaggc ctccccagag gctcccagag ctgctgggtg      480

gccggctggg gatatataga agagaaagcc cccaggccat catctatact gatggaggca      540

cgtgtggatc tcatcgacct ggacttgtgt aactcgaccc agtggtacaa tgggcgcgtt      600

cagccaacca atgtgtgcgc ggggtatcct gtaggcaaga tcgacacctg ccagggagac      660

agcggcgggc ctctcatgtg caaagacagc aaggaaagcg cctatgtggt cgtgggaatc      720

acaagctggg gggtaggctg tgcccgtgcc aagcgccccg gaatctacac ggccacctgg      780

ccctatctga actggatcgc ctccaagatt ggttctaacg ctttgcgtgt gattcaatcg      840

gccacccctc cacctcccac cactcgaccg cccccgattc gacccccctt ctcccaccct      900

atctctgctc accttccttg gtatttccaa ccgccccctc gaccacttcc accccgacca      960

ccggcagccc agccccgacc cccaccttca cccccgcccc cacccccacc tccagcctca     1020

cctttacccc cacccccacc cccaccccca cctacaccct catctaccac aaaacttccc     1080

caaggacttt cttttgccaa gcgcctacag cagctcatag aggtcttgaa ggggaagacc     1140

tattccgacg gaaagaacca ttatgacatg gagaccacag agctcccaga actgacctcg     1200

acctcc                                                                1206


<210>  5155
<211>  894
<212>  DNA
<213>  Homo Sapiens

<400>  5155
ataccagtta aacaggctga ttctggaagt tctgaggaaa agcagcttta caacaaatac       60

ccagatgctg tggccacatg gctaaaccct gacccatctc agaagcagaa tctcctagcc      120

ccacagaatg ctgtgtcctc tgaagaaacc aatgacttta aacaagagac ccttccaagt      180

aagtccaacg aaagccatga ccacatggat gatatggatg atgaagatga tgatgaccat      240

gtggacagcc aggactccat tgactcgaac gactctgatg atgtagatga cactgatgat      300

tctcaccagt ctgatgagtc tcaccattct gatgaatctg atgaactggt cactgatttt      360

cccacggacc tgccagcaac cgaagttttc actccagttg tccccacagt agacacatat      420

gatggccgag gtgatagtgt ggtttatgga ctgaggtcaa aatctaagaa gtttcgcaga      480

cctgacatcc agtaccctga tgctacagac gaggacatca cctcacacat ggaaagcgag      540

gagttgaatg gtgcatacaa ggccatcccc gttgcccagg acctgaacgc gccttctgat      600

tgggacagcc gtgggaagga cagttatgaa acgagtcagc tggatgacca gagtgctgaa      660

acccacagcc acaagcagtc cagattatat aagcggaaag ccaatgatga gagcaatgag      720

cattccgatg tgattgatag tcaggaactt tccaaagtca gccgtgaatt ccacagccat      780

gaatttcaca gccatgaaga tatgctggtt gtagacccca aaagtaagga agaagataaa      840

cacctgaaat ttcgtatttc tcatgaatta gatagtgcat cttctgaggt caat            894


<210>  5156
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  5156
gcccccgacc aggacgagat ccagcgcctc cccgggctgg ccaagcagcc gtctttccgc       60

cagtactccg gctacctcaa aggctccggc tccaagcacc tccactactg gtttgtggag      120

tcccagaagg atcccgagaa cagccctgtg gtgctttggc tcaatggggg tcccggctgc      180

agctcactag atgggctcct cacagagcat ggccccttcc tggtccagcc agatggtgtc      240

accctggagt acaaccccta ttcttggaat ctgattgcca atgtgttata cctggagtcc      300

ccagctgggg tgggcttctc ctactccgat gacaagtttt atgcaactaa tgacactgag      360

gtcgcccaga gcaattttga ggcccttcaa gatttcttcc gcctctttcc ggagtacaag      420

aacaacaaac ttttcctgac cggggagagc tatgctggca tctacatccc caccctggcc      480

gtgctggtca tgcaggatcc cagcatgaac cttcaggggc tggctgtggg caatggactc      540

tcctcctatg agcagaatga caactccctg gtctactttg cctactacca tggccttctg      600

gggaacaggc tttggtcttc tctccagacc cactgctgct ctcaaaacaa gtgtaacttc      660

tatgacaaca aagacctgga atgcgtgacc aatcttcagg aagtggcccg catcgtgggc      720

aactctggcc tcaacatcta caatctctat gccccgtgtg ctggaggggt gcccagccat      780

tttaggtatg agaaggacac tgttgtggtc caggatttgg gcaacatctt cactcgcctg      840

ccactcaagc ggatgtggca tcaggcactg ctgcgctcag gggataaagt gcgcatggac      900

cccccctgca ccaacacaac agctgcttcc acctacctca acaacccgta cgtgcggaag      960

gccctcaaca tcccggagca gctgccacaa tgggacatgt gcaactttct ggtaaactta     1020

cagtaccgcc gtctctaccg aagcatgaac tcccagtatc tgaagctgct tagctcacag     1080

aaataccaga tcctattata taatggagat gtagacatgg cctgcaattt catgggggat     1140

gagtggtttg tggattccct caaccagaag atggaggtgc agcgccggcc ctggttagtg     1200

aagtacgggg acagcgggga gcagattgcc ggcttcgtga aggagttctc ccacatcgcc     1260

tttctcacga tcaagggcgc cggccacatg gttcccaccg acaagcccct cgctgccttc     1320

accatgttct cccgcttcct gaacaagcag ccatac                               1356


<210>  5157
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  5157
ctccctgtga acagccctat gaataaaggg gataccgagg tgatgaaatg catcgttgag       60

gtcatctccg acacactttc caagcccagc cccatgcctg tcagccagga atgttttgag      120

acactccgag gagatgaacg gatcctttcc attctgagac atcagaattt actgaaggag      180

ctccaagacc tcgctctcca aggcgccaag gagagggcac atcagcagaa gaaacacagc      240

ggttttgaag atgaactctc agaggttctt gagaaccaga gcagccaggc cgagctgaaa      300

gaggcggtgg aagagccatc atccaaggat gttatggag                             339


<210>  5158
<211>  1452
<212>  DNA
<213>  Homo Sapiens

<400>  5158
atcatcccag ttgaggagga gaacccggac ttctggaacc gcgaggcagc cgaggccctg       60

ggtgccgcca agaagctgca gcctgcacag acagccgcca agaacctcat catcttcctg      120

ggcgatggga tgggggtgtc tacggtgaca gctgccagga tcctaaaagg gcagaagaag      180

gacaaactgg ggcctgagtt acccctggcc atggaccgct tcccatatgt ggctctgtcc      240

aagacataca atgtagacaa acatgtgcca gacagtggag ccacagccac ggcctacctg      300

tgcggggtca agggcaactt ccagaccatt ggcttgagtg cagccgcccg ctttaaccag      360

tgcaacacga cacgcggcaa cgaggtcatc tccgtgatga atcgggccaa gaaagcaggg      420

aagtcagtgg gagtggtaac caccacacga gtgcagcacg cctcgccagc cggcacctac      480

gcccacacgg tgaaccgcaa ctggtactcg gacgccgacg tgcctgcctc ggcccgccag      540

gaggggtgcc aggacatcgc tacgcagctc atctccaaca tggacattga cgtgatccta      600

ggtggaggcc gaaagtacat gtttcgcatg ggaaccccag accctgagta cccagatgac      660

tacagccaag gtgggaccag gctggacggg aagaatctgg tgcaggaatg gctggcgaag      720

cgccagggtg cccggtacgt gtggaaccgc actgagctca tgcaggcttc cctggacccg      780

tctgtgaccc atctcatggg tctctttgag cctggagaca tgaaatacga gatccaccga      840

gactccacac tggacccctc cctgatggag atgacagagg ctgccctgcg cctgctgagc      900

aggaaccccc gcggcttctt cctcttcgtg gagggtggtc gcatcgacca tggtcatcat      960

gaaagcaggg cttaccgggc actgactgag acgatcatgt tcgacgacgc cattgagagg     1020

gcgggccagc tcaccagcga ggaggacacg ctgagcctcg tcactgccga ccactcccac     1080

gtcttctcct tcggaggcta ccccctgcga gggagctcca tcttcgggct ggcccctggc     1140

aaggcccggg acaggaaggc ctacacggtc ctcctatacg gaaacggtcc aggctatgtg     1200

ctcaaggacg gcgcccggcc ggatgttacc gagagcgaga gcgggagccc cgagtatcgg     1260

cagcagtcag cagtgcccct ggacgaagag acccacgcag gcgaggacgt ggcggtgttc     1320

gcgcgcggcc cgcaggcgca cctggttcac ggcgtgcagg agcagacctt catagcgcac     1380

gtcatggcct tcgccgcctg cctggagccc tacaccgcct gcgacctggc gccccccgcc     1440

ggcaccaccg ac                                                         1452


<210>  5159
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  5159
ttcgccagag ctgaagctga agaagatggg gacctgcagt gcctgtgtgt gaagaccacc       60

tcccaggtcc gtcccaggca catcaccagc ctggaggtga tcaaggccgg accccactgc      120

cccactgccc aactcatagc cacgctgaag aatgggagga aaatttgctt ggatctgcaa      180

gccctgctgt acaagaaaat cattaaggaa catttggaga gt                         222


<210>  5160
<211>  1281
<212>  DNA
<213>  Homo Sapiens

<400>  5160
gaccagacgg tctcagacaa tgagctccag gaaatgtcca atcagggaag taagtacgtc       60

aataaggaaa ttcaaaatgc tgtcaacggg gtgaaacaga taaagactct catagaaaaa      120

acaaacgaag agcgcaagac actgctcagc aacctagaag aagccaagaa gaagaaagag      180

gatgccctaa atgagaccag ggaatcagag acaaagctga aggagctccc aggagtgtgc      240

aatgagacca tgatggccct ctgggaagag tgtaagccct gcctgaaaca gacctgcatg      300

aagttctacg cacgcgtctg cagaagtggc tcaggcctgg ttggccgcca gcttgaggag      360

ttcctgaacc agagctcgcc cttctacttc tggatgaatg gtgaccgcat cgactccctg      420

ctggagaacg accggcagca gacgcacatg ctggatgtca tgcaggacca cttcagccgc      480

gcgtccagca tcatagacga gctcttccag gacaggttct tcacccggga gccccaggat      540

acctaccact acctgccctt cagcctgccc caccggaggc ctcacttctt ctttcccaag      600

tcccgcatcg tccgcagctt gatgcccttc tctccgtacg agcccctgaa cttccacgcc      660

atgttccagc ccttccttga gatgatacac gaggctcagc aggccatgga catccacttc      720

catagcccgg ccttccagca cccgccaaca gaattcatac gagaaggcga cgatgaccgg      780

actgtgtgcc gggagatccg ccacaactcc acgggctgcc tgcggatgaa ggaccagtgt      840

gacaagtgcc gggagatctt gtctgtggac tgttccacca acaacccctc ccaggctaag      900

ctgcggcggg agctcgacga atccctccag gtcgctgaga ggttgaccag gaaatacaac      960

gagctgctaa agtcctacca gtggaagatg ctcaacacct cctccttgct ggagcagctg     1020

aacgagcagt ttaactgggt gtcccggctg gcaaacctca cgcaaggcga agaccagtac     1080

tatctgcggg tcaccacggt ggcttcccac acttctgact cggacgttcc ttccggtgtc     1140

actgaggtgg tcgtgaagct ctttgactct gatcccatca ctgtgacggt ccctgtagaa     1200

gtctccagga agaaccctaa atttatggag accgtggcgg agaaagcgct gcaggaatac     1260

cgcaaaaagc accgggagga g                                               1281


<210>  5161
<211>  1908
<212>  DNA
<213>  Homo Sapiens

<400>  5161
gaggaggagg acaagaagga ggacgtgggc acggtggtcg gcatcgacct ggggaccacc       60

tactcctgcg tcggcgtgtt caagaacggc cgcgtggaga tcatcgccaa cgatcagggc      120

aaccgcatca cgccgtccta tgtcgccttc actcctgaag gggaacgtct gattggcgat      180

gccgccaaga accagctcac ctccaacccc gagaacacgg tctttgacgc caagcggctc      240

atcggccgca cgtggaatga cccgtctgtg cagcaggaca tcaagttctt gccgttcaag      300

gtggttgaaa agaaaactaa accatacatt caagttgata ttggaggtgg gcaaacaaag      360

acatttgctc ctgaagaaat ttctgccatg gttctcacta aaatgaaaga aaccgctgag      420

gcttatttgg gaaagaaggt tacccatgca gttgttactg taccagccta ttttaatgat      480

gcccaacgcc aagcaaccaa agacgctgga actattgctg gcctaaatgt tatgaggatc      540

atcaacgagc ctacggcagc tgctattgct tatggcctgg ataagaggga gggggagaag      600

aacatcctgg tgtttgacct gggtggcgga accttcgatg tgtctcttct caccattgac      660

aatggtgtct tcgaagttgt ggccactaat ggagatactc atctgggtgg agaagacttt      720

gaccagcgtg tcatggaaca cttcatcaaa ctgtacaaaa agaagacggg caaagatgtc      780

aggaaagaca atagagctgt gcagaaactc cggcgcgagg tagaaaaggc caaacgggcc      840

ctgtcttctc agcatcaagc aagaattgaa attgagtcct tctatgaagg agaagacttt      900

tctgagaccc tgactcgggc caaatttgaa gagctcaaca tggatctgtt ccggtctact      960

atgaagcccg tccagaaagt gttggaagat tctgatttga agaagtctga tattgatgaa     1020

attgttcttg ttggtggctc gactcgaatt ccaaagattc agcaactggt taaagagttc     1080

ttcaatggca aggaaccatc ccgtggcata aacccagatg aagctgtagc gtatggtgct     1140

gctgtccagg ctggtgtgct ctctggtgat caagatacag gtgacctggt actgcttgat     1200

gtatgtcccc ttacacttgg tattgaaact gtgggaggtg tcatgaccaa actgattcca     1260

aggaacacag tggtgcctac caagaagtct cagatctttt ctacagcttc tgataatcaa     1320

ccaactgtta caatcaaggt ctatgaaggt gaaagacccc tgacaaaaga caatcatctt     1380

ctgggtacat ttgatctgac tggaattcct cctgctcctc gtggggtccc acagattgaa     1440

gtcacctttg agatagatgt gaatggtatt cttcgagtga cagctgaaga caagggtaca     1500

gggaacaaaa ataagatcac aatcaccaat gaccagaatc gcctgacacc tgaagaaatc     1560

gaaaggatgg ttaatgatgc tgagaagttt gctgaggaag acaaaaagct caaggagcgc     1620

attgatacta gaaatgagtt ggaaagctat gcctattctc taaagaatca gattggagat     1680

aaagaaaagc tgggaggtaa actttcctct gaagataagg agaccatgga aaaagctgta     1740

gaagaaaaga ttgaatggct ggaaagccac caagatgctg acattgaaga cttcaaagct     1800

aagaagaagg aactggaaga aattgttcaa ccaattatca gcaaactcta tggaagtgca     1860

ggccctcccc caactggtga agaggataca gcagaaaaag atgagttg                  1908


<210>  5162
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  5162
cttggacaaa gcctgaaacc agagccattt ggaagaagag ctcaagctgt tgaaacaaac       60

aaaacgctgc atgagatgaa gaccagattc ctgctctttg gagaaaccaa tcagggctgt      120

cagattcgaa tcaatcatcc ggacacgtta caggagtgcg gcttcaactc ctccctgcct      180

ctggtgatga taatccacgg gtggtcggtg gacggcgtgc tagaaaactg gatctggcag      240

atggtggccg cgctgaagtc tcagccggcc cagccagtga acgtggggct ggtggactgg      300

atcaccctgg cccacgacca ctacaccatc gccgtccgca acacccgcct tgtgggcaag      360

gaggtcgcgg ctcttctccg gtggctggag gaatctgttc aactctctcg aagccatgtt      420

cacctaattg ggtacagcct gggtgcacac gtgtcaggat ttgccggcag ttccatcggt      480

ggaacgcaca agattgggag aatcacaggg ctggatgccg cgggaccttt gtttgaggga      540

agtgccccca gcaatcgtct ttctccagat gatgccaatt ttgtggatgc cattcatacc      600

tttacgcggg agcacatggg cctgagcgtg ggcatcaaac agcccatagg acactatgac      660

ttctatccca acgggggctc cttccagcct ggctgccact tcctagagct ctacagacat      720

attgcccagc acggcttcaa tgccatcacc cagaccataa aatgctccca cgagcgatcg      780

gtgcaccttt tcatcgactc cttgctgcac gccggcacgc agagcatggc ctacccgtgt      840

ggtgacatga acagcttcag ccagggcctg tgcctgagct gcaagaaggg ccgctgcaac      900

acgctgggct accacgtccg ccaggagccg cggagcaaga gcaagaggct cttcctcgta      960

acgcgagccc agtccccctt caaagtttat cattaccagt taaagatcca gttcatcaac     1020

caaactgaga cgccaataca aacaactttt accatgtcac tactcggaac aaaagagaaa     1080

atgcagaaaa ttcccatcac tctgggcaaa ggaattgcta gtaataaaac gtattccttt     1140

cttatcacgc tggatgtgga tatcggcgag ctgatcatga tcaagttcaa gtgggaaaac     1200

agtgcagtgt gggccaatgt ctgggacacg gtccagacca tcatcccatg gagcacaggg     1260

ccgcgccact caggcctcgt tctgaagacg atcagagtca aagcaggaga aacccagcaa     1320

agaatgacat tttgttcaga aaacacagat gacctactac ttcgcccaac ccaggaaaaa     1380

atcttcgtga aatgtgaaat aaagtctaaa acatcaaagc gaaagatcag a              1431


<210>  5163
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  5163
tcggaggcgg agggtcgact ccgggagaaa cttttctctg gctatgatag ctccgtgcgg       60

ccagcgcggg aggtgggaga ccgtgtcagg gtcagcgttg gtctcatcct ggcgcaactc      120

atcagcctga acgagaagga tgaagagatg agcacaaagg tgtacttaga cctggagtgg      180

actgactaca ggctgagctg ggaccctgcg gagcacgacg gcatcgattc gctccgcatc      240

acggcggaat ccgtgtggct ccctgacgtg gtgctactga acaacaatga tgggaatttt      300

gacgtggctc tggacattag cgtcgtggtg tcctccgacg gctccgtgcg ttggcaaccc      360

ccgggcatct atcgcagcag ctgcagcatc caggtcacct acttcccctt cgactggcag      420

aattgcacta tggtgttcag ctcctacagc tacgacagct cggaggtcag cctgcagaca      480

ggcctgggtc ctgacgggca agggcatcag gaaatccaca ttcatgaagg gactttcatt      540

gagaatggcc agtgggagat tatccacaag ccctctcggc taatccagcc tccaggcgat      600

cctaggggag ggagggaagg acagcgccag gaagtcatct tctacctcat catccgccgc      660

aag                                                                    663


<210>  5164
<211>  1428
<212>  DNA
<213>  Homo Sapiens

<400>  5164
tgctccaaag gcacctcgca cgaggcaggc atcgtgtgcc gcatcaccaa gcctgccctc       60

ctggtgttga accacgagac tgccaaggtg atccagaccg ccttccagcg agccagctac      120

ccagatatca cgggcgagaa ggccatgatg ctccttggcc aagtcaagta tgggttgcac      180

aacatccaga tcagccactt gtccatcgcc agcagccagg tggagctggt ggaagccaag      240

tccattgatg tctccattca gaacgtgtct gtggtcttca aggggaccct gaagtatggc      300

tacaccactg cctggtggct gggtattgat cagtccattg acttcgagat cgactctgcc      360

attgacctcc agatcaacac acagctgacc tgtgactctg gtagagtgcg gaccgatgcc      420

cctgactgct acctgtcttt ccataagctg ctcctgcatc tccaagggga gcgagagcct      480

gggtggatca agcagctgtt cacaaatttc atctccttca ccctgaagct ggtcctgaag      540

ggacagatct gcaaagagat caacgtcatc tctaacatca tggccgattt tgtccagaca      600

agggctgcca gcatcctttc agatggagac attggggtgg acatttccct gacaggtgat      660

cccgtcatca cagcctccta cctggagtcc catcacaagg gtcatttcat ctacaagaat      720

gtctcagagg acctccccct ccccaccttc tcgcccacac tgctggggga ctcccgcatg      780

ctgtacttct ggttctctga gcgagtcttc cactcgctgg ccaaggtagc tttccaggat      840

ggccgcctca tgctcagcct gatgggagac gagttcaagg cagtgctgga gacctggggc      900

ttcaacacca accaggaaat cttccaagag gttgtcggcg gcttccccag ccaggcccaa      960

gtcaccgtcc actgcctcaa gatgcccaag atctcctgcc aaaacaaggg agtcgtggtc     1020

aattcttcag tgatggtgaa attcctcttt ccacgcccag accagcaaca ttctgtagct     1080

tacacatttg aagaggatat cgtgactacc gtccaggcct cctattctaa gaaaaagctc     1140

ttcttaagcc tcttggattt ccagattaca ccaaagactg tttccaactt gactgagagc     1200

agctccgagt ccatccagag cttcctgcag tcaatgatca ccgctgtggg catccctgag     1260

gtcatgtctc ggctcgaggt agtgtttaca gccctcatga acagcaaagg cgtgagcctc     1320

ttcgacatca tcaaccctga gattatcact cgagatggct tcctgctgct gcagatggac     1380

tttggcttcc ctgagcacct gctggtggat ttcctccaga gcttgagc                  1428


<210>  5165
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  5165
gagatctgcc cgagctttca gcgtgtcatc gaaaccctcc tcatggacac accctccagt       60

tatgaggctg ccatggaact tttcagccct gatcaagaca tgagggaggc aggggctcag      120

ctgaagaagc tggtggacac cctcccccaa aagcccagag aaagcatcat taagctcatg      180

gaaaaaatag cccaaagctc actgtgtaat                                       210


<210>  5166
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  5166
cagccggtgc tgcatcagcc gccggccatg tcctcggccc ttggaaccac aatccgcctc       60

acctgcaccc tgaggaacga ccatgacatc ggtgtgtaca gcgtctactg gtaccagcag      120

aggccgggcc accctcccag gttcctgctg agatatttct cacaatcaga caagagccag      180

ggcccccagg tcccccctcg cttctctgga tccaaagatg tggccaggaa cagggggtat      240

ttgagcatct ctgagctgca gcctgaggac gaggctatgt attactgtgc tatgggggcc      300

cgcagctcgg agaaggagga gagggagagg gagtgggagg aagaaatgga acccactgca      360

gccaggacac gtgtccct                                                    378


<210>  5167
<211>  2997
<212>  DNA
<213>  Homo Sapiens

<400>  5167
cagcagcagg aggtcatctc gccggacact accgagagaa acaacaactg cccagagaag       60

accgactgcc ccatccacgt gtacttcgtg ctggacacct cggagagcgt caccatgcag      120

tcccccacgg acatcctgct cttccacatg aagcagttcg tgccgcagtt catcagccag      180

ctgcagaacg agttctacct ggaccaggtg gcgctgagct ggcgctacgg cggcctgcac      240

ttctctgacc aggtggaggt gttcagccca ccgggcagcg accgggcctc cttcatcaag      300

aacctgcagg gcatcagctc cttccgccgc ggcaccttca ccgactgcgc gctggccaac      360

atgacggagc agatccggca ggaccgcagc aagggcaccg tccacttcgc cgtggtcatc      420

accgacggcc acgtcaccgg cagcccctgc gggggcatca agctgcaggc cgagcgggcc      480

cgcgaggagg gcatccggct cttcgccgtg gcccccaacc agaacctgaa ggagcagggc      540

ctgcgggaca tcgccagcac gccgcacgag ctctaccgca acgactacgc caccatgctg      600

cccgactcca ccgagatcga ccaggacacc atcaaccgca tcatcaaggt catgaaacac      660

gaagcctacg gagagtgcta caaggtgagc tgcctggaaa tccctgggcc ctctggcccc      720

aagggctacc gtggacagaa gggtgccaag ggcaacatgg gtgagccggg agagcctggc      780

cagaagggaa gacagggaga cccgggcatc gaaggcccca ttggattccc aggacccaag      840

ggcgttcctg gcttcaaagg agagaagggt gaatttggag ccgacggtcg caagggggcc      900

cctggcctgg ctggcaagaa cgggaccgat ggacagaagg gcaagctggg gcgcatcgga      960

cctcctggct gcaagggaga ccctggaaac cggggccccg acggttaccc gggggaagca     1020

gggagtccag gggagcgagg agaccaaggc ggcaaggggg accctggccg cccaggacgc     1080

agagggcccc cgggagaaat cggggccaag ggaagcaagg ggtatcaagg caacaatgga     1140

gccccaggaa gtcctggtgt gaaaggagcc aagggcgggc ctgggccccg cggacccaaa     1200

ggcgagccgg ggcgcagggg agaccccggc accaagggca gcccaggcag cgatggcccc     1260

aagggggaga agggggaccc tggccctgag gggccccgcg gcctggctgg agaggttggc     1320

aacaaaggag ccaagggaga ccgaggcttg cctggaccca gaggccccca gggagctctt     1380

ggggagcccg gaaagcaggg atctcgggga gaccccggtg atgcaggacc ccgtggagac     1440

tcaggacagc caggccccaa gggagacccc ggcaggcctg gattcagcta cccaggaccc     1500

cgaggagcac ccggagaaaa aggcgagccc ggcccacgcg gccccgaggg aggccgaggc     1560

gactttggct tgaaaggaga acctgggagg aaaggagaga aaggagagcc tgcggatcct     1620

ggtccccctg gtgagccagg ccctcggggg ccaagaggag tcccaggacc cgagggtgag     1680

cccggccccc ctggagaccc cggtctcacg gagtgtgacg tcatgaccta cgtgagggag     1740

acctgcgggt gctgcgactg tgagaagcgc tgtggcgccc tggacgtggt cttcgtcatc     1800

gacagctccg agagcattgg gtacaccaac ttcacactgg agaagaactt cgtcatcaac     1860

gtggtcaaca ggctgggtgc catcgctaag gaccccaagt ccgagacagg gacgcgtgtg     1920

ggcgtggtgc agtacagcca cgagggcacc tttgaggcca tccagctgga cgacgaacgt     1980

atcgactccc tgtcgagctt caaggaggct gtcaagaacc tcgagtggat tgcgggcggc     2040

acctggacac cctcagccct caagtttgcc tacgaccgcc tcatcaagga gagccggcgc     2100

cagaagacac gtgtgtttgc ggtggtcatc acggacgggc gccacgaccc tcgggacgat     2160

gacctcaact tgcgggcgct gtgcgaccgc gacgtcacag tgacggccat cggcatcggg     2220

gacatgttcc acgagaagca cgagagtgaa aacctctact ccatcgcctg cgacaagcca     2280

cagcaggtgc gcaacatgac gctgttctcc gacctggtcg ctgagaagtt catcgatgac     2340

atggaggacg tcctctgccc ggaccctcag atcgtgtgcc cagaccttcc ctgccaaaca     2400

gagctgtccg tggcacagtg cacgcagcgg cccgtggaca tcgtcttcct gctggacggc     2460

tccgagcggc tgggtgagca gaacttccac aaggcccggc gcttcgtgga gcaggtggcg     2520

cggcggctga cgctggcccg gagggacgac gaccctctca acgcacgcgt ggcgctgctg     2580

cagtttggtg gccccggcga gcagcaggtg gccttcccgc tgagccacaa cctcacggcc     2640

atccacgagg cgctggagac cacgcaatac ctgaactcct tctcgcacgt gggcgcaggc     2700

gtggtgcacg ccatcaatgc catcgtgcgc agcccgcgtg gcggggcccg gaggcacgca     2760

gagctgtcct tcgtgttcct cacggacggc gtcacgggca acgacagtct gcacgagtcg     2820

gcgcactcca tgcgcaagca gaacgtggta cccaccgtgc tggccttggg cagcgacgtg     2880

gacatggacg tgctcaccac gctcagcctg ggtgaccgtg ccgccgtgtt ccacgagaag     2940

gactatgaca gcctggcgca acccggcttc ttcgaccgct tcatccgctg gatctgc        2997


<210>  5168
<211>  1941
<212>  DNA
<213>  Homo Sapiens

<400>  5168
aacagaagaa attattacat tgctgctgaa gaaatatcct gggattattc agaatttgta       60

caaagggaaa cagatattga agactctgat gatattccag aagataccac atataagaaa      120

gtagtttttc gaaagtacct cgacagcact tttaccaaac gtgatcctcg aggggagtat      180

gaagagcatc tcggaattct tggtcctatt atcagagctg aagtggatga tgttatccaa      240

gttcgtttta aaaatttagc atccagaccg tattctctac atgcccatgg actttcctat      300

gaaaaatcat cagagggaaa gacttatgaa gatgactctc ctgaatggtt taaggaagat      360

aatgctgttc agccaaatag cagttatacc tacgtatggc atgccactga gcgatcaggg      420

ccagaaagtc ctggctctgc ctgtcgggct tgggcctact actcagctgt gaacccagaa      480

aaagatattc actcaggctt gataggtccc ctcctaatct gccaaaaagg aatactacat      540

aaggacagca acatgcctat ggacatgaga gaatttgtct tactatttat gacctttgat      600

gaaaagaaga gctggtacta tgaaaagaag tcccgaagtt cttggagact cacatcctca      660

gaaatgaaaa aatcccatga gtttcacgcc attaatggga tgatctacag cttgcctggc      720

ctgaaaatgt atgagcaaga gtgggtgagg ttacacctgc tgaacatagg cggctcccaa      780

gacattcacg tggttcactt tcacggccag accttgctgg aaaatggcaa taaacagcac      840

cagttagggg tctggcccct tctgcctggt tcatttaaaa ctcttgaaat gaaggcatca      900

aaacctggct ggtggctcct aaacacagag gttggagaaa accagagagc agggatgcaa      960

acgccatttc ttatcatgga cagagactgt aggatgccaa tgggactaag cactggtatc     1020

atatctgatt cacagatcaa ggcttcagag tttctgggtt actgggagcc cagattagca     1080

agattaaaca atggtggatc ttataatgct tggagtgtag aaaaacttgc agcagaattt     1140

gcctctaaac cttggatcca ggtggacatg caaaaggaag tcataatcac agggatccag     1200

acccaaggtg ccaaacacta cctgaagtcc tgctatacca cagagttcta tgtagcttac     1260

agttccaacc agatcaactg gcagatcttc aaagggaaca gcacaaggaa tgtgatgtat     1320

tttaatggca attcagatgc ctctacaata aaagagaatc agtttgaccc acctattgtg     1380

gctagatata ttaggatctc tccaactcga gcctataaca gacctaccct tcgattggaa     1440

ctgcaaggtt gtgaggtaaa tggatgttcc acacccctgg gtatggaaaa tggaaagata     1500

gaaaacaagc aaatcacagc ttcttcgttt aagaaatctt ggtggggaga ttactgggaa     1560

cccttccgtg cccgtctgaa tgcccaggga cgtgtgaatg cctggcaagc caaggcaaac     1620

aacaataagc agtggctaga aattgatcta ctcaagatca agaagataac ggcaattata     1680

acacagggct gcaagtctct gtcctctgaa atgtatgtaa agagctatac catccactac     1740

agtgagcagg gagtggaatg gaaaccatac aggctgaaat cctccatggt ggacaagatt     1800

tttgaaggaa atactaatac caaaggacat gtgaagaact ttttcaaccc cccaatcatt     1860

tccaggttta tccgtgtcat tcctaaaaca tggaatcaaa gtattgcact tcgcctggaa     1920

ctctttggct gtgatattta c                                               1941


<210>  5169
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  5169
gctgtgtctg aacatcagct cctccatgac aaggggaagt ccatccaaga tttacggcga       60

cgattcttcc ttcaccatct gatcgcagaa atccacacag ctgaaatcag agctacctcg      120

gaggtgtccc ctaactccaa gccctctccc aacacaaaga accaccccgt ccgatttggg      180

tctgatgatg agggcagata cctaactcag gaaactaaca aggtggagac gtacaaagag      240

cagccgctca agacacctgg gaagaaaaag aaaggcaagc ccgggaaacg caaggagcag      300

gaaaagaaaa aacggcgaac tcgctctgcc tggttagact ctggagtgac tgggagtggg      360

ctagaagggg accacctgtc tgacacctcc acaacgtcgc tggagctcga ttcacgg         417


<210>  5170
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5170
attattggag gaaatgaagt aactcctcat tcaagaccct acatggtcct acttagtctt       60

gacagaaaaa ccatctgtgc tggggctttg attgcaaaag actgggtgtt gactgcagct      120

cactgtaact tgaacaaaag gtcccaggtc attcttgggg ctcactcaat aaccagggaa      180

gagccaacaa aacagataat gcttgttaag aaagagtttc cctatccatg ctatgaccca      240

gccacacgcg aaggtgacct taaactttta cagctgacgg aaaaagcaaa aattaacaaa      300

tatgtgacta tccttcatct acctaaaaag ggggatgatg tgaaaccagg aaccatgtgc      360

caagttgcag ggtggggcag gactcacaat agtgcatctt ggtccgatac tctgagagaa      420

gtcaatatca ccatcataga cagaaaagtc tgcaatgatc gaaatcacta taattttaac      480

cctgtgattg gaatgaatat ggtttgtgct ggaagcctcc gaggtggaag agactcgtgc      540

aatggagatt ctggaagccc tttgttgtgc gagggtgttt tccgaggggt cacttccttt      600

ggccttgaaa ataaatgcgg agaccctcgt gggcctggtg tctatattct tctctcaaag      660

aaacacctca actggataat tatgactatc aagggagcag tt                         702


<210>  5171
<211>  399
<212>  DNA
<213>  Homo Sapiens

<400>  5171
agacccccac agtttacgag ggctcagtgg tttgccatcc agcacatcag tctgaacccc       60

cctcgatgca ccattgcaat gcgggcaatt aacaattatc gatggcgttg caaaaaccaa      120

aatacttttc ttcgtacaac ttttgctaat gtagttaatg tttgtggtaa ccaaagtata      180

cgctgccctc ataacagaac tctcaacaat tgtcatcgga gtagattccg ggtgccttta      240

ctccactgtg acctcataaa tccaggtgca cagaatattt caaactgcag gtatgcagac      300

agaccaggaa ggaggttcta tgtagttgca tgtgacaaca gagatccacg ggattctcca      360

cggtatcctg tggttccagt tcacctggat accaccatc                             399


<210>  5172
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  5172
ttcgtcccca tcttcaccta tggcgaactc cagaggatgc aggaaaagga acggaataaa       60

gggcaaaaga aatccctgag tgtatggcag aggtctgggg aggaaggtcc tgtagaccct      120

gcggagccca tcagggaaga agaaaacgaa atgatcaagc tgactgctcc tctggaaatt      180

ggaatgagga tgaactccag acagctggaa aagtacccgg ccaccctgga agggctgctg      240

agtgagatgc ttccccagca tgcagccaag                                       270


<210>  5173
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  5173
aatgcaccgc ttgtcaatgt gaccctctac tatgaagcac tgtgcggtgg ctgccgagcc       60

ttcctgatcc gggagctctt cccaacatgg ctgttggtca tggagatcct caatgtcacg      120

ctggtgccct acggaaacgc acaggaacaa aatgtcagtg gcaggtggga gttcaagtgc      180

cagcatggag aagaggagtg caaattcaac aaggtggagg cctgcgtgtt ggatgaactt      240

gacatggagc tagccttcct gaccattgtc tgcatggaag agtttgagga catggagaga      300

agtctgccac tatgcctgca gctctacgcc ccagggctgt cgccagacac tatcatggag      360

tgtgcaatgg gggaccgcgg catgcagctc atgcacgcca acgcccagcg gacagatgct      420

ctccagccac cacacgagta tgtgccctgg gtcaccgtca atgggaaacc cttggaagat      480

cagacccagc tccttaccct tgtctgccag ttgtaccagg gcaag                      525


<210>  5174
<211>  1761
<212>  DNA
<213>  Homo Sapiens

<400>  5174
cagagaaacc agctgcttca gaaagaacca gacctcaggt tggaaaatgt ccaaaagttt       60

cccagtcctg aaatgatcag ggctttggag tacatagaaa acctccgaca acaagctcat      120

aaggaagaaa gcagcccaga ttataatccc taccaaggtg tctctgtccc ccttcagcaa      180

aaagaaaatg gcgatgaaag ccacttgccc gagagggatt cactgagtga agaagactgg      240

atgagaataa tactcgaagc tttgagacag gctgaaaatg agcctcagtc tgcaccaaaa      300

gaaaataagc cctatgcctt gaattcagaa aagaactttc caatggacat gagtgatgat      360

tatgagacac agcagtggcc agaaagaaag cttaagcaca tgcaattccc tcctatgtat      420

gaagagaatt ccagggataa cccctttaaa cgcacaaatg aaatagtgga ggaacaatat      480

actcctcaaa gccttgctac attggaatct gtcttccaag agctggggaa actgacagga      540

ccaaacaacc agaaacgtga gaggatggat gaggagcaaa aactttatac ggatgatgaa      600

gatgatatct acaaggctaa taacattgcc tatgaagatg tggtcggggg agaagactgg      660

aacccagtag aggagaaaat agagagtcaa acccaggaag aggtgagaga cagcaaagag      720

aatatagaaa aaaatgaaca aatcaatgat gagatgaaac gctcagggca gcttggcatc      780

caggaagaag gtcttcggaa agagagtaaa gaccaactct cagatgatgt ctccaaagta      840

attgcctatt tgaaaaggtt agtaaatgct gcaggaagtg ggaggttaca gaatgggcaa      900

aatggggaaa gggccaccag gctttttgag aaacctcttg attctcagtc tatttatcag      960

ctgattgaaa tctcaaggaa tttacagata cccccagaag acttaattga gatgctcaaa     1020

actggggaga agccgaatgg atcagtggaa ccggagcggg agcttgacct tcctgttgac     1080

ctagatgaca tctcagaggc tgacttagac catccagacc tgttccaaaa taggatgctc     1140

tccaagagtg gctaccctaa aacacctggt ggtgctggga ctgaggccct accagacggg     1200

ctcagtgttg aggatatttt aaatctttta gggatggaga gtgcagcaaa tcagaaaacg     1260

tcgtattttc ccaatccata taaccaggag aaagttctgc caaggctccc ttatggtgct     1320

ggaagatcta gatcgaacca gcttcccaaa gctgcctgga ttccacatgt tgaaaacaga     1380

cagatggcat atgaaaacct gaacgacaag gatcaagaat taggtgagta cttggccagg     1440

atgctagtta aataccctga gatcattaat tcaaaccaag tgaagcgagt tcctggtcaa     1500

ggctcatctg aaggtgacct gcaggaagag gaacaaattg agcaggccat caaagagcat     1560

ttgaatcaag gcagctctca ggagactgac aagctggccc cggtgagcaa aaggttccct     1620

gtggggcccc cgaagaatga tgatacccca aataggcagt actgggatga agatctgtta     1680

atgaaagtgc tggaatacct caaccaagaa aaggcagaaa agggaaggga gcatattgct     1740

aagagagcaa tggaaaatat g                                               1761


<210>  5175
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  5175
ttctcttact ttgtgatcct ggcagaaaat ggcttcttgc ccggcaacct ggtgggcatc       60

cggctgaact gggatgaccg caccgtcaat gacctggaag acagttacgg gcagcagtgg      120

acatacgagc agaggaaggt ggtggagttc acctgc                                156


<210>  5176
<211>  1875
<212>  DNA
<213>  Homo Sapiens

<400>  5176
gtggcgggtg ccgagggccc ggacgaggat tcttctaaca gagaaaatgc cattgaggat       60

gaagaggagg aggaggagga agatgatgat gaggaagaag acgacttgga agttaaggaa      120

gaaaatggag tcttggtcct aaatgatgca aactttgata attttgtggc tgacaaagac      180

acagtgctgc tggagtttta tgctccatgg tgtggacatt gcaagcagtt tgctccggaa      240

tatgaaaaaa ttgccaacat attaaaggat aaagatcctc ccattcctgt tgccaagatc      300

gatgcaacct cagcgtctgt gctggccagc aggtttgatg tgagtggcta ccccaccatc      360

aagatcctta agaaggggca ggctgtagac tacgagggct ccagaaccca ggaagaaatt      420

gttgccaagg tcagagaagt ctcccagccc gactggacgc ctccaccaga agtcacgctt      480

gtgttgacca aagagaactt tgatgaagtt gtgaatgatg cagatatcat tctggtggag      540

ttttatgccc catggtgtgg acactgcaag aaacttgccc ccgagtatga gaaggccgcc      600

aaggagctca gcaagcgttc tcctccaatt cccctggcaa aggtcgacgc caccgcagaa      660

acagacctgg ccaagaggtt tgatgtctct ggctatccca ccctgaaaat tttccgcaaa      720

ggaaggcctt atgactacaa cggcccacga gaaaaatatg gaatcgttga ttacatgatc      780

gagcagtccg ggcctccctc caaggagatt ctgaccctga agcaggtcca ggagttcctg      840

aaggatggag acgatgtcat catcatcggg gtctttaagg gggagagtga cccagcctac      900

cagcaatacc aggatgccgc taacaacctg agagaagatt acaaatttca ccacactttc      960

agcacagaaa tagcaaagtt cttgaaagtc tcccaggggc agttggttgt aatgcagcct     1020

gagaaattcc agtccaagta tgagccccgg agccacatga tggacgtcca gggctccacc     1080

caggactcgg ccatcaagga cttcgtgctg aagtacgccc tgcccctggt tggccaccgc     1140

aaggtgtcaa acgatgctaa gcgctacacc aggcgccccc tggtggtcgt ctactacagt     1200

gtggacttca gctttgatta cagagctgca actcagtttt ggcggagcaa agtcctagag     1260

gtggccaagg atttccctga gtacaccttt gccattgcgg acgaagagga ctatgctggg     1320

gaggtgaagg acctggggct cagcgagagt ggggaggatg tcaatgccgc catcctggac     1380

gagagtggga agaagttcgc catggagcca gaggagtttg actctgacac cctccgcgag     1440

tttgtcactg ctttcaaaaa aggaaaactg aagccagtca tcaaatccca gccagtgccc     1500

aagaacaaca agggacccgt caaggtcgtg gtgggaaaga cctttgactc cattgtgatg     1560

gaccccaaga aggacgtcct catcgagttc tacgcgccat ggtgcgggca ctgcaagcag     1620

ctagagcccg tgtacaacag cctggccaag aagtacaagg gccaaaaggg cctggtcatc     1680

gccaagatgg acgccactgc caacgacgtc cccagcgacc gctataaggt ggagggcttc     1740

cccaccatct acttcgcccc cagtggggac aaaaagaacc cagttaaatt tgagggtgga     1800

gacagagatc tggagcattt gagcaagttt atagaagaac atgccacaaa actgagcagg     1860

accaaggaag agctt                                                      1875


<210>  5177
<211>  1551
<212>  DNA
<213>  Homo Sapiens

<400>  5177
catccaggct tttttacttc aattggtcag atgactgatt tgatccatac tgagaaagat       60

ctggtgactt ctctgaaaga ttatattaag gcagaagagg acaagttaga acaaataaaa      120

aaatgggcag agaagttaga tcggctaact agtacagcga caaaagatcc agaaggattt      180

gttgggcatc cagtaaatgc attcaaatta atgaaacgtc tgaatactga gtggagtgag      240

ttggagaatc tggtccttaa ggatatgtca gatggcttta tctctaacct aaccattcag      300

agacagtact ttcctaatga tgaagatcag gttggggcag ccaaagctct gttacgtctc      360

caggatacct acaatttgga tacagatacc atctcaaagg gtaatcttcc aggagtgaaa      420

cacaaatctt ttctaacggc tgaggactgc tttgagttgg gcaaagtggc ctatacagaa      480

gcagattatt accatacgga actgtggatg gaacaagccc taaggcaact ggatgaaggc      540

gagatttcta ccatagataa agtctctgtt ctagattatt tgagctatgc ggtatatcag      600

cagggagacc tggataaggc acttttgctc acaaagaagc ttcttgaact agatcctgaa      660

catcagagag ctaatggtaa cttaaaatat tttgagtata taatggctaa agaaaaagat      720

gtcaataagt ctgcttcaga tgaccaatct gatcagaaaa ctacaccaaa gaaaaaaggg      780

gttgctgtgg attacctgcc agagagacag aagtacgaaa tgctgtgccg tggggagggt      840

atcaaaatga cccctcggag acagaaaaaa ctcttttgcc gctaccatga tggaaaccgt      900

aatcctaaat ttattctggc tccagctaaa caggaggatg aatgggacaa gcctcgtatt      960

attcgcttcc atgatattat ttctgatgca gaaattgaaa tcgtcaaaga cctagcaaaa     1020

ccaaggctga ggcgagccac catttcaaac ccaataacag gagacttgga gacggtacat     1080

tacagaatta gcaaaagtgc ctggctctct ggctatgaaa atcctgtggt gtctcgaatt     1140

aatatgagaa tacaagatct aacaggacta gatgtttcca cagcagagga attacaggta     1200

gcaaattatg gagttggagg acagtatgaa ccccattttg actttgcacg gaaagatgag     1260

ccagatgctt tcaaagagct ggggacagga aatagaattg ctacatggct gttttatatg     1320

agtgatgtgt ctgcaggagg agccactgtt tttcctgaag ttggagctag tgtttggccc     1380

aaaaaaggaa ctgctgtttt ctggtataat ctgtttgcca gtggagaagg agattatagt     1440

acacggcatg cagcctgtcc agtgctagtt ggcaacaaat gggtatccaa taaatggctc     1500

catgaacgtg gacaagaatt tcgaagacct tgtacgttgt cagaattgga a              1551


<210>  5178
<211>  912
<212>  DNA
<213>  Homo Sapiens

<400>  5178
gccacccctg ccctgcgctt tgtagccgtg ggtgactggg gaggggtccc caatgcccca       60

ttccacacgg cccgggaaat ggccaatgcc aaggagatcg ctcggactgt gcagatcctg      120

ggtgcagact tcatcctgtc tctaggggac aatttttact tcactggtgt gcaagacatc      180

aatgacaaga ggttccagga gacctttgag gacgtattct ctgaccgctc ccttcgcaaa      240

gtgccctggt acgtgctagc cggaaaccat gaccaccttg gcaatgtctc tgcccagatt      300

gcatactcta agatctccaa gcgctggaac ttccccagcc ctttctaccg cctgcacttc      360

aagatcccac agaccaatgt gtctgtggcc atttttatgc tggacacagt gacactatgt      420

ggcaactcag atgacttcct cagccagcag cctgagaggc cccgagacgt gaagctggcc      480

cgcacacagc tgtcctggct caagaaacag ctggcggcgg ccagggagga ctacgtgctg      540

gtggctggcc actaccccgt gtggtccata gccgagcacg ggcctaccca ctgcctggtc      600

aagcagctac ggccactgct ggccacatac ggggtcactg cctacctgtg cggccacgat      660

cacaatctgc agtacctgca agatgagaat ggcgtgggct acgtgctgag tggggctggg      720

aatttcatgg acccctcaaa gcggcaccag cgcaaggtcc ccaacggcta tctgcgcttc      780

cactatggga ctgaagactc actgggtggc tttgcctatg tggagatcag ctccaaagag      840

atgactgtca cttacatcga ggcctcgggc aagtccctct ttaagaccag gctgccgagg      900

cgagccaggc cc                                                          912


<210>  5179
<211>  588
<212>  DNA
<213>  Homo Sapiens

<400>  5179
gcggctatag gcagctgctc gaaagagtac cgcgtgctcc ttggccagct ccagaagcag       60

acagatctca tgcaggacac cagcagactc ctggacccct atatacgtat ccaaggcctg      120

gatgttccta aactgagaga gcactgcagg gagcgccccg gggccttccc cagtgaggag      180

accctgaggg ggctgggcag gcggggcttc ctgcagaccc tcaatgccac actgggctgc      240

gtcctgcaca gactggccga cttagagcag cgcctcccca aggcccagga tttggagagg      300

tctgggctga acatcgagga cttggagaag ctgcagatgg cgaggccgaa catcctcggg      360

ctcaggaaca acatctactg catggcccag ctgctggaca actcagacac ggctgagccc      420

acgaaggctg gccggggggc ctctcagccg cccaccccca cccctgcctc ggatgctttt      480

cagcgcaagc tggagggctg caggttcctg catggctacc atcgcttcat gcactcagtg      540

gggcgggtct tcagcaagtg gggggagagc ccgaaccgga gccggaga                   588


<210>  5180
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  5180
ggggacaccc aaccacgttt cttggagcag gctaagtgtg agtgtcattt cctcaatggg       60

acggagcgag tgtggaacct gatcagatac atctataacc aagaggagta cgcgcgctac      120

aacagtgacc tgggggagta ccaggcggtg acggagctgg ggcggcctga cgctgagtac      180

tggaacagcc agaaggacct cctggagcgg aggcgggccg aggtggacac ctactgcaga      240

tacaactacg gggttgtgga gagcttcaca gtgcagcggc gagtccaacc taaggtgact      300

gtgtatcctt caaagaccca gcccctgcag caccacaacc tcctggtctg ctctgtgaat      360

ggtttctatc caggcagcat tgaagtcagg tggttccgga acggccagga agagaaggct      420

ggggtggtgt ccacaggcct gatccagaat ggagactgga ccttccagac cctggtgatg      480

ctggaaacag ttcctcggag tggagaggtt tacacctgcc aagtggagca tccaagcatg      540

atgagccctc tcacggtgca atggagtgca cggtctgaat ctgcacagag caag            594


<210>  5181
<211>  240
<212>  DNA
<213>  Homo Sapiens

<400>  5181
cgcaacagca aagaggagcg tattgacctg gatgcggaag aggagaacat ccaagaaggc       60

cctaaggaga ccattgaaat agaaacacaa gttcctgaga agaaaaaagg aatcttcagg      120

agagcctatg acctattttg tgggctagag cagcacggtg cacccaagat gactgaggaa      180

gaggagaaag ccatgaagat gaagatgacg gacacctctg agaagccttt gtggaggaca      240


<210>  5182
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  5182
atccagttca ccgagtcctg ctcaatggac cagagtgcca aggaacccct catcaactac       60

ttggatatgg aatacttcgg cactatctcc attggctccc caccacagaa cttcactgtc      120

atcttcgaca ctggctcctc caacctctgg gtcccctctg tgtactgcac tagcccagcc      180

tgcaagacgc acagcaggtt ccagccttcc cagtccagca catacagcca gccaggtcaa      240

tctttctcca ttcagtatgg aaccgggagc ttgtccggga tcattggagc cgaccaagtc      300

tctgtggaag gactaaccgt ggttggccag cagtttggag aaagtgtcac agagccaggc      360

cagacctttg tggatgcaga gtttgatgga attctgggcc tgggataccc ctccttggct      420

gtgggaggag tgactccagt atttgacaac atgatggctc agaacctggt ggacttgccg      480

atgttttctg tctacatgag cagtaaccca gaaggtggtg cggggagcga gctgattttt      540

ggaggctacg accactccca tttctctggg agcctgaatt gggtcccagt caccaagcaa      600

gcttactggc agattgcact ggataacatc caggtgggag gcactgttat gttctgctcc      660

gagggctgcc aggccattgt ggacacaggg acttccctca tcactggccc ttccgacaag      720

attaagcagc tgcaaaacgc cattggggca gcccccgtgg atggagaata tgctgtggag      780

tgtgccaacc ttaacgtcat gccggatgtc accttcacca ttaacggagt cccctatacc      840

ctcagcccaa ctgcctacac cctactggac ttcgtggatg gaatgcagtt ctgcagcagt      900

ggctttcaag gacttgacat ccaccctcca gctgggcccc tctggatcct gggggatgtc      960

ttcattcgac agttttactc agtctttgac cgtgggaata accgtgtggg actggcccca     1020

gcagtcccc                                                             1029


<210>  5183
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  5183
accatgtgca gtgcccagga caggactgat ctcctcaatg tctgtatgga tgccaagcac       60

cacaagacaa agccaggtcc tgaggacaag ctgcatgacc aatgcagtcc ctggaagaag      120

aatgcctgct gcacagccag caccagccag gagctgcaca aggacacctc ccgcctgtac      180

aactttaact gggaccactg cggcaagatg gagcccgcct gcaagcgcca cttcatccag      240

gacacctgtc tctatgagtg ctcacccaac ctggggccct ggatccagca ggtgaatcag      300

agctggcgca aagaacgctt cctggatgtg cccttatgca aagaggactg tcagcgctgg      360

tgggaggatt gtcacacctc ccacacgtgc aagagcaact ggcacagagg atgggactgg      420

acctcaggag ttaacaagtg cccagctggg gctctctgcc gcacctttga gtcctacttc      480

cccactccag ctgccctttg tgaaggcctc tggagtcact catacaaggt cagcaactac      540

agccgaggga gcggccgctg catccagatg tggtttgatt cagcccaggg caaccccaac      600

gaggaagtgg cgaggttcta tgctgcagcc atgcatgtga at                         642


<210>  5184
<211>  1218
<212>  DNA
<213>  Homo Sapiens

<400>  5184
ctggatttca actaccaccg ccaggaaggg atggaagcgt ttttgaagac tgttgcccaa       60

aactacagtt ctgtcactca cttacacagt attgggaaat ctgtgaaagg tagaaacctg      120

tgggttcttg ttgtggggcg gtttccaaag gaacacagaa ttgggattcc agagttcaaa      180

tacgtggcaa atatgcatgg agatgagact gttgggcggg agctgctgct ccatctgatt      240

gactatctcg taaccagtga tggcaaagac cctgaaatca caaatctgat caatagtacc      300

cggatacaca tcatgccttc catgaaccca gatggatttg aagccgtcaa aaagcctgac      360

tgttactaca gcatcggaag ggaaaattat aaccagtatg acttgaatcg aaatttcccc      420

gatgcttttg aatataataa tgtctcaagg cagcctgaaa ctgtggcagt catgaagtgg      480

ctgaaaacag agacgtttgt cctctctgca aacctccatg gtggtgccct cgtggccagt      540

tacccatttg ataatggtgt tcaagcaact ggggcattat actcccgaag cttaacgcct      600

gatgatgatg tttttcaata tcttgcacat acctatgctt caagaaatcc caacatgaag      660

aaaggagacg agtgtaaaaa caaaatgaac tttcctaatg gtgttacaaa tggatactct      720

tggtatccac tccaaggtgg aatgcaagat tacaactaca tctgggccca gtgttttgaa      780

attacgttgg agctgtcatg ctgtaaatat cctcgtgagg agaagcttcc atccttttgg      840

aataataaca aagcctcatt aattgaatat ataaagcagg tgcacctagg tgtaaagggt      900

caagtttttg atcagaatgg aaatccatta cccaatgtaa ttgtggaagt ccaagacaga      960

aaacatatct gcccctatag aaccaacaaa tatggagagt attatctcct tctcttgcct     1020

gggtcttata taataaatgt tacagtccct ggacatgatc cacacatcac aaaggtgatt     1080

attccggaga aatcccagaa cttcagtgct cttaaaaagg atattctact tccattccaa     1140

gggcaattgg attctatccc agtatcaaat ccttcatgcc caatgattcc tctatacaga     1200

aatttgccag accactca                                                   1218


<210>  5185
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5185
gaccataccc ccaagtacca ggaccgactg gccacaccgg gcttgatgat tcgccccaag       60

actgagaacc ttgatgtcat tgtcaatgtc agtgacactg aaagctggga ccagcatgtt      120

cagaagctca acaagttctt ggagccttac aacgactcta tccaagccca aaagaatgat      180

gtctgccgcc ctgggcgcta ttacgaacag ccagataatg gagtcctcaa ctaccccaaa      240

cgtgcctgcc aattcaaccg gacccagctg ggcaactgct ccggcattgg ggactccacc      300

cactatggtt acagcactgg gcagccctgt gtcttcatca agatgaaccg ggtcatcaac      360

ttctatgcag gagcaaacca gagcatgaat gttacctgtg ctgggaagcg agatgaagat      420

gctgagaatc tcggcaactt cgtcatgttc cccgccaacg gcaacatcga cctcatgtac      480

ttcccctact atggcaaaaa gttccacgtg aactacacac agcccctggt ggctgtgaag      540

ttcctgaatg tgacccccaa cgtggaggtg aatgtagaat gtcgcatcaa cgccgccaac      600

atcgccacag acgatgagcg agacaagttc gccggccgcg tggccttcaa actccgcatc      660

aacaaaacc                                                              669


<210>  5186
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  5186
aatttggtga atttccacag aatgatcaag ttgacgacag gaaaggaagc cgcactcagt       60

tatggcttct acggctgcca ctgtggcgtg ggtggcagag gatcccccaa ggatgcaacg      120

gatcgctgct gtgtcactca tgactgttgc tacaaacgtc tggagaaacg tggatgtggc      180

accaaatttc tgagctacaa gtttagcaac tcggggagca gaatcacctg tgcaaaacag      240

gactcctgca gaagtcaact gtgtgagtgt gataaggctg ctgccacctg ttttgctaga      300

aacaagacga cctacaataa aaagtaccag tactattcca ataaacactg cagagggagc      360

acccctcgtt gc                                                          372


<210>  5187
<211>  2346
<212>  DNA
<213>  Homo Sapiens

<400>  5187
gacgatgaag ttgatgtgga tggtacagta gaagaggatc tgggtaaaag tagagaagga       60

tcaaggacgg atgatgaagt agtacagaga gaggaagaag ctattcagtt ggatggatta      120

aatgcatcac aaataagaga acttagagag aagtcggaaa agtttgcctt ccaagccgaa      180

gttaacagaa tgatgaaact tatcatcaat tcattgtata aaaataaaga gattttcctg      240

agagaactga tttcaaatgc ttctgatgct ttagataaga taaggctaat atcactgact      300

gatgaaaatg ctctttctgg aaatgaggaa ctaacagtca aaattaagtg tgataaggag      360

aagaacctgc tgcatgtcac agacaccggt gtaggaatga ccagagaaga gttggttaaa      420

aaccttggta ccatagccaa atctgggaca agcgagtttt taaacaaaat gactgaagca      480

caggaagatg gccagtcaac ttctgaattg attggccagt ttggtgtcgg tttctattcc      540

gccttccttg tagcagataa ggttattgtc acttcaaaac acaacaacga tacccagcac      600

atctgggagt ctgactccaa tgaattttct gtaattgctg acccaagagg aaacactcta      660

ggacggggaa cgacaattac ccttgtctta aaagaagaag catctgatta ccttgaattg      720

gatacaatta aaaatctcgt caaaaaatat tcacagttca taaactttcc tatttatgta      780

tggagcagca agactgaaac tgttgaggag cccatggagg aagaagaagc agccaaagaa      840

gagaaagaag aatctgatga tgaagctgca gtagaggaag aagaagaaga aaagaaacca      900

aagactaaaa aagttgaaaa aactgtctgg gactgggaac ttatgaatga tatcaaacca      960

atatggcaga gaccatcaaa agaagtagaa gaagatgaat acaaagcttt ctacaaatca     1020

ttttcaaagg aaagtgatga ccccatggct tatattcact ttactgctga aggggaagtt     1080

accttcaaat caattttatt tgtacccaca tctgctccac gtggtctgtt tgacgaatat     1140

ggatctaaaa agagcgatta cattaagctc tatgtgcgcc gtgtattcat cacagacgac     1200

ttccatgata tgatgcctaa atacctcaat tttgtcaagg gtgtggtgga ctcagatgat     1260

ctccccttga atgtttcccg cgagactctt cagcaacata aactgcttaa ggtgattagg     1320

aagaagcttg ttcgtaaaac gctggacatg atcaagaaga ttgctgatga taaatacaat     1380

gatacttttt ggaaagaatt tggtaccaac atcaagcttg gtgtgattga agaccactcg     1440

aatcgaacac gtcttgctaa acttcttagg ttccagtctt ctcatcatcc aactgacatt     1500

actagcctag accagtatgt ggaaagaatg aaggaaaaac aagacaaaat ctacttcatg     1560

gctgggtcca gcagaaaaga ggctgaatct tctccatttg ttgagcgact tctgaaaaag     1620

ggctatgaag ttatttacct cacagaacct gtggatgaat actgtattca ggcccttccc     1680

gaatttgatg ggaagaggtt ccagaatgtt gccaaggaag gagtgaagtt cgatgaaagt     1740

gagaaaacta aggagagtcg tgaagcagtt gagaaagaat ttgagcctct gctgaattgg     1800

atgaaagata aagcccttaa ggacaagatt gaaaaggctg tggtgtctca gcgcctgaca     1860

gaatctccgt gtgctttggt ggccagccag tacggatggt ctggcaacat ggagagaatc     1920

atgaaagcac aagcgtacca aacgggcaag gacatctcta caaattacta tgcgagtcag     1980

aagaaaacat ttgaaattaa tcccagacac ccgctgatca gagacatgct tcgacgaatt     2040

aaggaagatg aagatgataa aacagttttg gatcttgctg tggttttgtt tgaaacagca     2100

acgcttcggt cagggtatct tttaccagac actaaagcat atggagatag aatagaaaga     2160

atgcttcgcc tcagtttgaa cattgaccct gatgcaaagg tggaagaaga gcccgaagaa     2220

gaacctgaag agacagcaga agacacaaca gaagacacag agcaagacga agatgaagaa     2280

atggatgtgg gaacagatga agaagaagaa acagcaaagg aatctacagc tgaaaaagat     2340

gaattg                                                                2346


<210>  5188
<211>  2934
<212>  DNA
<213>  Homo Sapiens

<400>  5188
atgaataatc cagccatcaa gagaatagga aatcacatta ccaagtctcc tgaagacaag       60

cgagaatatc gagggctaga gctggccaat ggtatcaaag tacttcttat cagtgatccc      120

accacggata agtcatcagc agcacttgat gtgcacatag gttcattgtc ggatcctcca      180

aatattgctg gcttaagtca tttttgtgaa catatgcttt ttttgggaac aaagaaatac      240

cctaaagaaa atgaatacag ccagtttctc agtgagcatg caggaagttc aaatgccttt      300

actagtggag agcataccaa ttactatttt gatgtttctc atgaacacct agaaggtgcc      360

ctagacaggt ttgcacagtt ttttctgtgc cccttgttcg atgaaagttg caaagacaga      420

gaggtgaatg cagttgattc agaacatgag aagaatgtga tgaatgatgc ctggagactc      480

tttcaattgg aaaaagctac agggaatcct aaacacccct tcagtaaatt tgggacaggt      540

aacaaatata ctctggagac tagaccaaac caagaaggca ttgatgtaag acaagagcta      600

ctgaaattcc attctgctta ctattcatcc aacttaatgg ctgtttgtgt tttaggtcga      660

gaatctttag atgacttgac taatctggtg gtaaagttat tttctgaagt agagaacaaa      720

aatgttccat tgccagaatt tcctgaacac cctttccaag aagaacatct taaacaactt      780

tacaaaatag tacccattaa agatattagg aatctctatg tgacatttcc catacctgac      840

cttcagaaat actacaaatc aaatcctggt cattatcttg gtcatctcat tgggcatgaa      900

ggtcctggaa gtctgttatc agaacttaag tcaaagggct gggttaatac tcttgttggt      960

gggcagaagg aaggagcccg aggttttatg ttttttatca ttaatgtgga cttgaccgag     1020

gaaggattat tacatgttga agatataatt ttgcacatgt ttcaatacat tcagaagtta     1080

cgtgcagaag gacctcaaga atgggttttc caagagtgca aggacttgaa tgctgttgct     1140

tttaggttta aagacaaaga gaggccacgg ggctatacat ctaagattgc aggaatattg     1200

cattattatc ccctagaaga ggtgctcaca gcggaatatt tactggaaga atttagacct     1260

gacttaatag agatggttct cgataaactc agaccagaaa atgtccgggt tgccatagtt     1320

tctaaatctt ttgaaggaaa aactgatcgc acagaagagt ggtatggaac ccagtacaaa     1380

caagaagcta taccggatga agtcatcaag aaatggcaaa atgctgacct gaatgggaaa     1440

tttaaacttc ctacaaagaa tgaatttatt cctacgaatt ttgagatttt accgttagaa     1500

aaagaggcga caccataccc tgctcttatt aaggatacag ctatgagcaa actttggttc     1560

aaacaagatg ataagttttt tttgccgaag gcttgtctca actttgaatt tttcagccca     1620

tttgcttatg tggacccctt gcactgtaac atggcctatt tgtaccttga gctcctcaaa     1680

gactcactca acgagtatgc atatgcagca gagctagcag gcttgagcta tgatctccaa     1740

aataccatct atgggatgta tctttcagtg aaaggttaca atgacaagca gccaatttta     1800

ctaaagaaga ttattgagaa aatggctacc tttgagattg atgaaaaaag atttgaaatt     1860

atcaaagaag catatatgcg atctcttaac aatttccggg ctgaacagcc tcaccagcat     1920

gccatgtact acctccgctt gctgatgact gaagtggcct ggactaaaga tgagttaaaa     1980

gaagctctgg atgatgtaac ccttcctcgc cttaaggcct tcatacctca gctcctgtca     2040

cggctgcaca ttgaagccct tctccatgga aacataacaa agcaggctgc attaggaatt     2100

atgcagatgg ttgaagacac cctcattgaa catgctcata ccaaacctct ccttccaagt     2160

cagctggttc ggtatagaga agttcagctc cctgacagag gatggtttgt ttatcagcag     2220

agaaatgaag ttcacaataa ctgtggcatc gagatatact accaaacaga catgcaaagc     2280

acctcagaga atatgtttct ggagctcttc tgtcagatta tctcggaacc ttgcttcaac     2340

accctgcgca ccaaggagca gttgggctat atcgtcttca gcgggccacg tcgagctaat     2400

ggcatacagg gcttgagatt catcatccag tcagaaaagc cacctcacta cctagaaagc     2460

agagtggaag ctttcttaat taccatggaa aagtccatag aggacatgac agaagaggcc     2520

ttccaaaaac acattcaggc attagcaatt cgtcgactag acaaaccaaa gaagctatct     2580

gctgagtgtg ctaaatactg gggagaaatc atctcccagc aatataattt tgacagagat     2640

aacactgagg ttgcatattt aaagacactt accaaggaag atatcatcaa attctacaag     2700

gaaatgttgg cagtagatgc tccaaggaga cataaggtat ccgtccatgt tcttgccagg     2760

gaaatggatt cttgtcctgt tgttggagag ttcccatgtc aaaatgacat aaatttgtca     2820

caagcaccag ccttgccaca acctgaagtg attcagaaca tgaccgaatt caagcgtggt     2880

ctgccactgt ttccccttgt gaaaccacat attaacttca tggctgcaaa actc           2934


<210>  5189
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  5189
gcgcgctcca ccgacacttt taactacgcc acctaccaca ccctggagga gatctatgac       60

ttcctggacc tgctggtggc ggagaacccg caccttgtca gcaagatcca gattggcaac      120

acctatgaag ggcgtcccat ttacgtgctg aagttcagca cggggggcag taagcgtcca      180

gccatctgga tcgacacggg catccattcc cgggagtggg tcacccaggc cagtggggtc      240

tggtttgcaa agaagatcac tcaagactac gggcaggatg cagctttcac cgccattctc      300

gacaccttgg acatcttcct ggagatcatc accaaccctg atggctttgc cttcacgcac      360

agcacgaatc gcatgtggcg caagactcgg tcccacacag caggctccct ctgtattggc      420

gtggacccca acaggaactg ggacgctggc tttgggttgt ccggagccag cagtaacccc      480

tgctcggaga cttaccgcgg caagtttgcc aattccgaag tggaggtcaa gtccattgta      540

gactttgtga aggaccatgg gaacatcaag gccttcatct ccatccacag ctactcccag      600

ctcctcatgt atccctatgg ctacaaaaca gaaccagtcc ctgaccagga tgagctggat      660

cagctttcca aggctgctgt gacagccctg gcctctctct acgggaccaa gttcaactat      720

ggcagcatca tcaaggcaat ttatcaagcc agtggaagca ctattgactg gacctacagc      780

cagggcatca agtactcctt caccttcgag ctccgggaca ctgggcgcta tggcttcctg      840

ctgccagcct cccagatcat ccccacagcc aaggagacgt ggctggcgct tctgaccatc      900

atggagcaca ccctgaatca cccctac                                          927


<210>  5190
<211>  921
<212>  DNA
<213>  Homo Sapiens

<400>  5190
gcaacaggac acagttatga gaagtacaac aagtgggaaa cgatagaggc ttggactcaa       60

caagtcgcca ctgagaatcc agccctcatc tctcgcagtg ttatcggaac cacatttgag      120

ggacgcgcta tttacctcct gaaggttggc aaagctggac aaaataagcc tgccattttc      180

atggactgtg gtttccatgc cagagagtgg atttctcctg cattctgcca gtggtttgta      240

agagaggctg ttcgtaccta tggacgtgag atccaagtga cagagcttct cgacaagtta      300

gacttttatg tcctgcctgt gctcaatatt gatggctaca tctacacctg gaccaagagc      360

cgattttgga gaaagactcg ctccacccat actggatcta gctgcattgg cacagacccc      420

aacagaaatt ttgatgctgg ttggtgtgaa attggagcct ctcgaaaccc ctgtgatgaa      480

acttactgtg gacctgccgc agagtctgaa aaggagacca aggccctggc tgatttcatc      540

cgcaacaaac tctcttccat caaggcatat ctgacaatcc actcgtactc ccaaatgatg      600

atctaccctt actcatatgc ttacaaactc ggtgagaaca atgctgagtt gaatgccctg      660

gctaaagcta ctgtgaaaga acttgcctca ctgcacggca ccaagtacac atatggcccg      720

ggagctacaa caatctatcc tgctgctggg ggctctgacg actgggctta tgaccaagga      780

atcagatatt ccttcacctt tgaacttcga gatacaggca gatatggctt tctccttcca      840

gaatcccaga tccgggctac ctgcgaggag accttcctgg caatcaagta tgttgccagc      900

tacgtcctgg aacacctgta c                                                921


<210>  5191
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  5191
atcccaggca ggcacagcta cgcaaaatac aataattggg aaaagattgt ggcttggact       60

gaaaagatga tggataagta tcctgaaatg gtctctcgta ttaaaattgg atctactgtt      120

gaagataatc cactatatgt tctgaagatt ggggaaaaga atgaaagaag aaaggctatt      180

tttatggatt gtggcattca cgcacgagaa tgggtctccc cagcattctg ccagtggttt      240

gtctatcagg caaccaaaac ttatgggaga aacaaaatta tgaccaaact cttggaccga      300

atgaattttt acattcttcc tgtgttcaat gttgatggat atatttggtc atggacaaag      360

aaccgcatgt ggagaaaaaa tcgttccaag aaccaaaact ccaaatgcat cggcactgac      420

ctcaacagga attttaatgc ttcatggaac tccattccta acaccaatga cccatgtgca      480

gataactatc ggggctctgc accagagtcc gagaaagaga cgaaagctgt cactaatttc      540

attagaagcc acctgaatga aatcaaggtt tacatcacct tccattccta ctcccagatg      600

ctattgtttc cctatggata tacatcaaaa ctgccaccta accatgagga cttggccaaa      660

gttgcaaaga ttggcactga tgttctatca actcgatatg aaacccgcta catctatggc      720

ccaatagaat caacaattta cccgatatca ggttcttctt tagactgggc ttatgacctg      780

ggcatcaaac acacatttgc ctttgagctc cgagataaag gcaaatttgg ttttctcctt      840

ccagaatccc ggataaagcc aacgtgcaga gagaccatgc tagctgtcaa atttattgcc      900

aagtatatcc tcaagcatac ttcc                                             924


<210>  5192
<211>  1314
<212>  DNA
<213>  Homo Sapiens

<400>  5192
gtgacctttc gccaccaccg ctatgatgat cttgtgcgga cgctgtacaa ggtgcaaaac       60

gaatgccccg gcatcacgcg ggtctacagc attgggcgca gcgtggaggg gagacacctc      120

tacgtgctgg agttcagcga ccaccctgga atccacgagc ccttggaacc agaggtcaag      180

tatgtgggga acatgcacgg caacgaagcg ttgggccgcg agctgatgct gcagctgtcg      240

gagtttctgt gcgaggagtt ccggaacagg aaccagcgca tcgtccagct catccaggac      300

acgcgcattc acatcctgcc atccatgaac cccgacggct acgaggtggc tgctgcccag      360

ggcccaaaca agcctgggta tctagttggc aggaacaatg caaatggagt ggacctgaac      420

cgcaacttcc ctgatctcaa tacctatatc tactataacg agaagtacgg aggccccaac      480

caccacctgc cccttccaga caactggaaa agtcaggtgg aacccgagac ccgggcggtg      540

atccggtgga tgcactcctt caactttgtt ctttcagcca atctccacgg aggggcggtg      600

gtggccaatt acccgtatga caagtccttt gagcaccggg tccgaggggt ccgccgcacc      660

gccagcaccc ccacgcctga cgacaagctc ttccagaagc tggccaaggt ctactcctat      720

gcacatggat ggatgttcca aggttggaac tgcggagatt acttcccaga tggcatcacc      780

aatggagctt cctggtattc tctcagcaag ggaatgcaag actttaatta tctccatacc      840

aactgctttg agatcacgct ggaactgagt tgcgacaagt ttccccccga agaggagtta      900

cagcgggagt ggctgggtaa tcgggaagcc ctaatccagt tcctggaaca ggttcaccag      960

ggcatcaagg gaatggtgct tgatgagaat tacaataatc tcgccaatgc tgtcatttct     1020

gtcagtggga ttaaccatga tgtcacttca ggtgaccatg gtgattactt ccggctgctg     1080

cttccaggta tctacactgt tagtgccaca gcacctgggt atgacccaga gacagtaact     1140

gtgaccgtgg gtcctgcgga accaacgttg gttaacttcc acctcaaaag aagcatccct     1200

caagtaagcc ctgtgaggag agctcccagc agaaggcacg gagtcagagc caaagtgcag     1260

ccccaagcca gaaagaaaga aatggagatg aggcagctgc agagaggccc tgcc           1314


<210>  5193
<211>  1467
<212>  DNA
<213>  Homo Sapiens

<400>  5193
cgtccgccca acatcgtgct gatctttgcc gacgacctcg gctatgggga cctgggctgc       60

tatgggcacc ccagctctac cactcccaac ctggaccagc tggcggcggg agggctgcgg      120

ttcacagact tctacgtgcc tgtgtctctg tgcacaccct ctagggccgc cctcctgacc      180

ggccggctcc cggttcggat gggcatgtac cctggcgtcc tggtgcccag ctcccggggg      240

ggcctgcccc tggaggaggt gaccgtggcc gaagtcctgg ctgcccgagg ctacctcaca      300

ggaatggccg gcaagtggca ccttggggtg gggcctgagg gggccttcct gcccccccat      360

cagggcttcc atcgatttct aggcatcccg tactcccacg accagggccc ctgccagaac      420

ctgacctgct tcccgccggc cactccttgc gacggtggct gtgaccaggg cctggtcccc      480

atcccactgt tggccaacct gtccgtggag gcgcagcccc cctggctgcc cggactagag      540

gcccgctaca tggctttcgc ccatgacctc atggccgacg cccagcgcca ggatcgcccc      600

ttcttcctgt actatgcctc tcaccacacc cactaccctc agttcagtgg gcagagcttt      660

gcagagcgtt caggccgcgg gccatttggg gactccctga tggagctgga tgcagctgtg      720

gggaccctga tgacagccat aggggacctg gggctgcttg aagagacgct ggtcatcttc      780

actgcagaca atggacctga gaccatgcgt atgtcccgag gcggctgctc cggtctcttg      840

cggtgtggaa agggaacgac ctacgagggc ggtgtccgag agcctgcctt ggccttctgg      900

ccaggtcata tcgctcccgg cgtgacccac gagctggcca gctccctgga cctgctgcct      960

accctggcag ccctggctgg ggccccactg cccaatgtca ccttggatgg ctttgacctc     1020

agccccctgc tgctgggcac aggcaagagc cctcggcagt ctctcttctt ctacccgtcc     1080

tacccagacg aggtccgtgg ggtttttgct gtgcggactg gaaagtacaa ggctcacttc     1140

ttcacccagg gctctgccca cagtgatacc actgcagacc ctgcctgcca cgcctccagc     1200

tctctgactg ctcatgagcc cccgctgctc tatgacctgt ccaaggaccc tggtgagaac     1260

tacaacctgc tggggggtgt ggccggggcc accccagagg tgctgcaagc cctgaaacag     1320

cttcagctgc tcaaggccca gttagacgca gctgtgacct tcggccccag ccaggtggcc     1380

cggggcgagg accccgccct gcagatctgc tgtcatcctg gctgcacccc ccgcccagct     1440

tgctgccatt gcccagatcc ccatgcc                                         1467


<210>  5194
<211>  1158
<212>  DNA
<213>  Homo Sapiens

<400>  5194
aaggagttga agtttgtgac tttggtgttt cggcatggag accgaagtcc cattgacacc       60

tttcccactg accccataaa ggaatcctca tggccacaag gatttggcca actcacccag      120

ctgggcatgg agcagcatta tgaacttgga gagtatataa gaaagaggta tagaaaattc      180

ttgaatgagt cctataaaca tgaacaggtt tatattcgaa gcacagacgt tgaccggact      240

ttgatgagtg ctatgacaaa cctggcagcc ctgtttcccc cagaaggtgt cagcatctgg      300

aatcctatcc tactctggca gcccatcccg gtgcacacag ttcctctttc tgaagatcag      360

ttgctatacc tgcctttcag gaactgccct cgttttcaag aacttgagag tgagactttg      420

aaatcagagg aattccagaa gaggctgcac ccttataagg attttatagc taccttggga      480

aaactttcag gattacatgg ccaggacctt tttggaattt ggagtaaagt ctacgaccct      540

ttatattgtg agagtgttca caatttcact ttaccctcct gggccactga ggacaccatg      600

actaagttga gagaattgtc agaattgtcc ctcctgtccc tctatggaat tcacaagcag      660

aaagagaaat ctaggctcca agggggtgtc ctggtcaatg aaatcctcaa tcacatgaag      720

agagcaactc agataccaag ctacaaaaaa cttatcatgt attctgcgca tgacactact      780

gtgagtggcc tacagatggc gctagatgtt tacaacggac tccttcctcc ctatgcttct      840

tgccacttga cggaattgta ctttgagaag ggggagtact ttgtggagat gtactatcgg      900

aatgagacgc agcacgagcc gtatcccctc atgctacctg gctgcagccc cagctgtcct      960

ctggagaggt ttgctgagct ggctggccct gtgatccctc aagactggtc cacggagtgt     1020

atgaccacaa acagccatca agttctaaag gtcatctttg ctgttgcctt ttgcctgata     1080

tctgctgtcc taatggtact actgtttatc cacattcgcc gtggactctg ctggcagaga     1140

gaatcctatg ggaacatc                                                   1158


<210>  5195
<211>  630
<212>  DNA
<213>  Homo Sapiens

<400>  5195
aggattgcat gggccaggac tgagcttctc aatgtctgca tgaacgccaa gcaccacaag       60

gaaaagccag gccccgagga caagttgcat gagcagtgtc gaccctggag gaagaatgcc      120

tgctgttcta ccaacaccag ccaggaagcc cataaggatg tttcctacct atatagattc      180

aactggaacc actgtggaga gatggcacct gcctgcaaac ggcatttcat ccaggacacc      240

tgcctctacg agtgctcccc caacttgggg ccctggatcc agcaggtgga tcagagctgg      300

cgcaaagagc gggtactgaa cgtgcccctg tgcaaagagg actgtgagca atggtgggaa      360

gattgtcgca cctcctacac ctgcaagagc aactggcaca agggctggaa ctggacttca      420

gggtttaaca agtgcgcagt gggagctgcc tgccaacctt tccatttcta cttccccaca      480

cccactgttc tgtgcaatga aatctggact cactcctaca aggtcagcaa ctacagccga      540

gggagtggcc gctgcatcca gatgtggttc gacccagccc agggcaaccc caatgaggag      600

gtggcgaggt tctatgctgc agccatgagt                                       630


<210>  5196
<211>  1548
<212>  DNA
<213>  Homo Sapiens

<400>  5196
gtcttcgggg tggctgcggg aacccggagg cccaacgtgg tgctgctcct cacggacgac       60

caggacgaag tgctcggcgg catgacaccg ctaaagaaaa ccaaagctct catcggagag      120

atggggatga ctttttccag tgcttatgtg ccaagtgctc tctgctgccc cagcagagcc      180

agtatcctga caggaaagta cccacataat catcacgttg tgaacaacac tctggagggg      240

aactgcagta gtaagtcctg gcagaagatc caagaaccaa atactttccc agcaattctc      300

agatcaatgt gtggttatca gacctttttt gcagggaaat atttaaatga gtacggagcc      360

ccagatgcag gtggactaga acacgttcct ctgggttgga gttactggta tgccttggaa      420

aagaattcta agtattataa ttacaccctg tctatcaatg ggaaggcacg gaagcatggt      480

gaaaactata gtgtggacta cctgacagat gttttggcta atgtctcctt ggactttctg      540

gactacaagt ccaactttga gcccttcttc atgatgatcg ccactccagc gcctcattcg      600

ccttggacag ctgcacctca gtaccagaag gctttccaga atgtctttgc accaagaaac      660

aagaacttca acatccatgg aacgaacaag cactggttaa ttaggcaagc caagactcca      720

atgactaatt cttcaataca gtttttagat aatgcattta ggaaaaggtg gcaaactctc      780

ctctcagttg atgaccttgt ggagaaactg gtcaagaggc tggagttcac tggggagctc      840

aacaacactt acatcttcta tacctcagac aatggctatc acacaggaca gttttccttg      900

ccaatagaca agagacagct gtatgagttt gatatcaaag ttccactgtt ggttcgagga      960

cctgggatca aaccaaatca gacaagcaag atgctggttg ccaacattga cttgggtcct     1020

actattttgg acattgctgg ctacgaccta aataagacac agatggatgg gatgtcctta     1080

ttgcccattt tgagaggtgc cagtaacttg acctggcgat cagatgtcct ggtggaatac     1140

caaggagaag gccgtaacgt cactgaccca acatgccctt ccctgagtcc tggcgtatct     1200

caatgcttcc cagactgtgt atgtgaagat gcttataaca atacctatgc ctgtgtgagg     1260

acaatgtcag cattgtggaa tttgcagtat tgcgagtttg atgaccagga ggtgtttgta     1320

gaagtctata atctgactgc agacccagac cagatcacta acattgctaa aaccatagac     1380

ccagagcttt taggaaagat gaactatcgg ttaatgatgt tacagtcctg ttctgggcca     1440

acctgtcgca ctccaggggt ttttgacccc ggatacaggt ttgacccccg tctcatgttc     1500

agcaatcgcg gcagtgtcag gactcgaaga ttttccaaac atcttctg                  1548


<210>  5197
<211>  582
<212>  DNA
<213>  Homo Sapiens

<400>  5197
tgcagctgct ccccggtgca cccgcaacag gcgttttgca atgcagatgt agtgatcagg       60

gccaaagcgg tcagtgagaa ggaagtggac tctggaaacg acatttatgg caaccctatc      120

aagaggatcc agtatgagat caagcagata aagatgttca aagggcctga gaaggatata      180

gagtttatct acacggcccc ctcctcggca gtgtgtgggg tctcgctgga cgttggagga      240

aagaaggaat atctcattgc aggaaaggcc gagggggacg gcaagatgca catcaccctc      300

tgtgacttca tcgtgccctg ggacaccctg agcaccaccc agaagaagag cctgaaccac      360

aggtaccaga tgggctgcga gtgcaagatc acgcgctgcc ccatgatccc gtgctacatc      420

tcctccccgg acgagtgcct ctggatggac tgggtcacag agaagaacat caacgggcac      480

caggccaagt tcttcgcctg catcaagaga agtgacggct cctgtgcgtg gtaccgcggc      540

gcggcgcccc ccaagcagga gtttctcgac atcgaggacc ca                         582


<210>  5198
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5198
agcacaacag cagtgcagac acccacctcc ggagagcctt tggtctctac tagcgagccc       60

ctgagctcaa agatgtacac cacttcaata acaagtgacc ctaaggccga cagcactggg      120

gaccagacct cagccctacc tccctcaact tccatcaatg agggatcccc tctttggact      180

tccattggtg ccagcactgg ttccccttta cctgagccaa caacctacca ggaagtttcc      240

atcaagatgt catcagtgcc ccaggaaacc cctcatgcaa ccagtcatcc tgctgttccc      300

ataacagcaa actctctagg atcccacacc gtgacaggtg gaaccataac aacgaactct      360

ccagaaacct ccagtaggac cagtggagcc cctgttacca cggcagctag ctctctggag      420

acctccagag gcacctctgg accccctctt accatggcaa ctgtctctct ggagacttcc      480

aaaggcacct ctggaccccc tgttaccatg gcaactgact ctctggagac ctccactggg      540

accactggac cccctgttac catgacaact ggctctctgg agccctccag cggggccagt      600

ggaccccagg tctctagcgt aaaactatct acaatgatgt ctccaacgac ctccaccaac      660

gcaagcactg tgcccttccg gaacccagat gagaactcac ga                         702


<210>  5199
<211>  1347
<212>  DNA
<213>  Homo Sapiens

<400>  5199
aaagaagttt gctacgaaag actcggctgc ttcagtgatg actccccatg gtcaggaatt       60

acggaaagac ccctccatat attgccttgg tctccaaaag atgtcaacac ccgcttcctc      120

ctatatacta atgagaaccc aaacaacttt caagaagttg ccgcagattc atcaagcatc      180

agtggctcca atttcaaaac aaatagaaaa actcgcttta ttattcatgg attcatagac      240

aagggagaag aaaactggct ggccaatgtg tgcaagaatc tgttcaaggt ggaaagtgtg      300

aactgtatct gtgtggactg gaaaggtggc tcccgaactg gatacacaca agcctcgcag      360

aacatcagga tcgtgggagc agaagtggca tattttgttg aatttcttca gtcggcgttc      420

ggttactcac cttccaacgt gcatgtcatt ggccacagcc tgggtgccca cgctgctggg      480

gaggctggaa ggagaaccaa tgggaccatt ggacgcatca cagggttgga cccagcagaa      540

ccttgctttc agggcacacc tgaattagtc cgattggacc ccagcgatgc caaatttgtg      600

gatgtaattc acacggatgg tgcccccata gtccccaatt tggggtttgg aatgagccaa      660

gtcgtgggcc acctagattt ctttccaaat ggaggagtgg aaatgcctgg atgtaaaaag      720

aacattctct ctcagattgt ggacatagac ggaatctggg aagggactcg agactttgcg      780

gcctgtaatc acttaagaag ctacaaatat tacactgata gcatcgtcaa ccctgatggc      840

tttgctggat tcccctgtgc ctcttacaac gtcttcactg caaacaagtg tttcccttgt      900

ccaagtggag gctgcccaca gatgggtcac tatgctgata gatatcctgg gaaaacaaat      960

gatgtgggcc agaaatttta tctagacact ggtgatgcca gtaattttgc acgttggagg     1020

tataaggtat ctgtcacact gtctggaaaa aaggttacag gacacatact agtttctttg     1080

ttcggaaata aaggaaactc taagcagtat gaaattttca agggcactct caaaccagat     1140

agtactcatt ccaatgaatt tgactcagat gtggatgttg gggacttgca gatggttaaa     1200

tttatttggt ataacaatgt gatcaaccca actttaccta gagtgggagc atccaagatt     1260

atagtggaga caaatgttgg aaaacagttc aacttctgta gtccagaaac cgtcagggag     1320

gaagttctgc tcaccctcac accgtgt                                         1347


<210>  5200
<211>  1947
<212>  DNA
<213>  Homo Sapiens

<400>  5200
cagaggatgt ttgaaattga ctatagccgg gactccttcc tcaaggatgg ccagccattt       60

cgctacatct caggaagcat tcactactcc cgtgtgcccc gcttctactg gaaggaccgg      120

ctgctgaaga tgaagatggc tgggctgaac gccatccaga cgtatgtgcc ctggaacttt      180

catgagccct ggccaggaca gtaccagttt tctgaggacc atgatgtgga atattttctt      240

cggctggctc atgagctggg actgctggtt atcctgaggc ccgggcccta catctgtgca      300

gagtgggaaa tgggaggatt acctgcttgg ctgctagaga aagagtctat tcttctccgc      360

tcctccgacc cagattacct ggcagctgtg gacaagtggt tgggagtcct tctgcccaag      420

atgaagcctc tcctctatca gaatggaggg ccagttataa cagtgcaggt tgaaaatgaa      480

tatggcagct actttgcctg tgattttgac tacctgcgct tcctgcagaa gcgctttcgc      540

caccatctgg gggatgatgt ggttctgttt accactgatg gagcacataa aacattcctg      600

aaatgtgggg ccctgcaggg cctctacacc acggtggact ttggaacagg cagcaacatc      660

acagatgctt tcctaagcca gaggaagtgt gagcccaaag gacccttgat caattctgaa      720

ttctatactg gctggctaga tcactggggc caacctcact ccacaatcaa gaccgaagca      780

gtggcttcct ccctctatga tatacttgcc cgtggggcga gtgtgaactt gtacatgttt      840

ataggtggga ccaattttgc ctattggaat ggggccaact caccctatgc agcacagccc      900

accagctacg actatgatgc cccactgagt gaggctgggg acctcactga gaagtatttt      960

gctctgcgaa acatcatcca gaagtttgaa aaagtaccag aaggtcctat ccctccatct     1020

acaccaaagt ttgcatatgg aaaggtcact ttggaaaagt taaagacagt gggagcagct     1080

ctggacattc tgtgtccctc tgggcccatc aaaagccttt atcccttgac atttatccag     1140

gtgaaacagc attatgggtt tgtgctgtac cggacaacac ttcctcaaga ttgcagcaac     1200

ccagcacctc tctcttcacc cctcaatgga gtccacgatc gagcatatgt tgctgtggat     1260

gggatccccc agggagtcct tgagcgaaac aatgtgatca ctctgaacat aacagggaaa     1320

gctggagcca ctctggacct tctggtagag aacatgggac gtgtgaacta tggtgcatat     1380

atcaacgatt ttaagggttt ggtttctaac ctgactctca gttccaatat cctcacggac     1440

tggacgatct ttccactgga cactgaggat gcagtgcgca gccacctggg gggctgggga     1500

caccgtgaca gtggccacca tgatgaagcc tgggcccaca actcatccaa ctacacgctc     1560

ccggcctttt atatggggaa cttctccatt cccagtggga tcccagactt gccccaggac     1620

acctttatcc agtttcctgg atggaccaag ggccaggtct ggattaatgg ctttaacctt     1680

ggccgctatt ggccagcccg gggccctcag ttgaccttgt ttgtgcccca gcacatcctg     1740

atgacctcgg ccccaaacac catcaccgtg ctggaactgg agtgggcacc ctgcagcagt     1800

gatgatccag aactatgtgc tgtgacgttc gtggacaggc cagttattgg ctcatctgtg     1860

acctacgatc atccctccaa acctgttgaa aaaagactca tgcccccacc cccgcaaaaa     1920

aacaaagatt catggctgga ccatgta                                         1947


<210>  5201
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  5201
caggaagaat gtgtctgtga aaactacaag ctggccgtaa actgctttgt gaataataat       60

cgtcaatgcc agtgtacttc agttggtgca caaaatactg tcatttgctc aaagctggct      120

gccaaatgtt tggtgatgaa ggcagaaatg aatggctcaa aacttgggag aagagcaaaa      180

cctgaagggg ccctccagaa caatgatggg ctttatgatc ctgactgcga tgagagcggg      240

ctctttaagg ccaagcagtg caacggcacc tccatgtgct ggtgtgtgaa cactgctggg      300

gtcagaagaa cagacaagga cactgaaata acctgctctg agcgagtgag aacctactgg      360

atcatcattg aactaaaaca caaagcaaga gaaaaacctt atgatagtaa aagtttgcgg      420

actgcacttc agaaggagat cacaacgcgt tatcaactgg atccaaaatt tatcacgagt      480

attttgtatg agaataatgt tatcactatt gatctggttc aaaattcttc tcaaaaaact      540

cagaatgatg tggacatagc tgatgtggct tattattttg aaaaagatgt taaaggtgaa      600

tccttgtttc attctaagaa aatggacctg acagtaaatg gggaacaact ggatctggat      660

cctggtcaaa ctttaattta ttatgttgat gaaaaagcac ctgaattctc aatgcagggt      720

ctaaaa                                                                 726


<210>  5202
<211>  1107
<212>  DNA
<213>  Homo Sapiens

<400>  5202
gacttctttc gggacgaggc agagaggatc atgagggact cccctgtcat tgatgggcac       60

aatgacctcc cctggcagct gctggatatg ttcaacaacc ggctgcagga cgagagggcc      120

aacctgacca ccttggccgg cacacacacc aacatcccca agctgagggc cggctttgtg      180

ggaggccagt tctggtccgt gtacacgccc tgcgacaccc agaacaaaga cgccgtgcgg      240

aggacgctgg agcagatgga cgtggtccac cgcatgtgcc ggatgtaccc ggagaccttc      300

ctgtatgtca ccagcagtgc aggcattcgg caggccttcc gggaagggaa ggtggccagc      360

ctgatcggcg tggagggcgg ccactccatt gacagcagtt tgggcgtcct gcgggcactc      420

tatcagctgg gcatgcggta cctgaccctc acccacagct gcaacacgcc ctgggctgac      480

aactggctgg tggacacggg agacagcgag ccccagagcc aaggcttgtc accctttggg      540

cagcgtgtgg tgaaggagct gaaccgtctg ggggtcctca tcgacttggc tcacgtgtct      600

gtggccacca tgaaggccac cctgcagctg tccagagccc cggtcatctt cagccactcc      660

tcggcctaca gcgtgtgcgc aagccggcgc aacgtgcctg acgacgtcct gaggctggtg      720

aaacagacag acagcctggt gatggtgaac ttctacaaca attacatttc ctgcaccaac      780

aaggccaacc tgtcccaagt ggccgaccat ctggatcaca tcaaggaggt ggcaggagcc      840

agagccgtgg gttttggtgg ggactttgat ggtgttccaa gggtccctga ggggctggag      900

gacgtctcca agtatccaga cctgatcgct gagctgctca ggaggaactg gacggaggcg      960

gaggtcaagg gcgcactggc tgacaacctg ctgagggtct tcgaggctgt ggaacaggcc     1020

agcaacctca cacaggctcc cgaggaggag cccatcccgc tggaccagct gggtggctcc     1080

tgcaggaccc attacggcta ctcctct                                         1107


<210>  5203
<211>  1587
<212>  DNA
<213>  Homo Sapiens

<400>  5203
ggttacagag acatcaatga gatcgacatc aacatgaacg atcctctttt tacaaagcag       60

tggtatctga tcaatactgg gcaagctgat ggcactcctg gccttgattt gaatgtggct      120

gaagcctggg agctgggata cacagggaaa ggtgttacca ttggaattat ggatgatggg      180

attgactatc tccacccgga cctggcctcc aactataatg ccgaagcaag ttacgacttc      240

agcagcaacg acccctatcc ttaccctcgg tacacagatg actggtttaa cagccacggg      300

acccgatgtg caggagaagt ttctgctgcc gccaacaaca atatctgtgg agttggagta      360

gcatacaact ccaaggttgc aggcatccgg atgctggacc agccattcat gacagacatc      420

atcgaggcct cctccatcag tcatatgcca cagctgattg acatctacag cgccagctgg      480

ggccccacag acaacggcaa gacagtggat gggccccggg agctcacgct gcaggccatg      540

gccgatggcg tgaacaaggg ccgcggcggc aaaggcagca tctacgtgtg ggcctccggg      600

gacggcggca gctatgacga ctgcaactgc gacggctacg cctccagcat gtggaccatc      660

tccatcaact cagccatcaa cgacggcagg actgccctgt acgacgagag ctgctcttcc      720

accttggctt ccaccttcag caacgggagg aaaaggaacc ccgaggccgg tgtggcaacc      780

acagatttgt acggcaactg cactctgagg cattctggga catctgcagc tgcccccgag      840

gcagctggtg tgtttgcact ggctctggag gctaacctgg gtctgacctg gcgggacatg      900

cagcatctga ctgtgctcac ctccaaacgg aaccagcttc acgacgaggt ccatcagtgg      960

cggcgcaatg gggtcggcct ggaatttaat cacctctttg gctacggggt ccttgatgca     1020

ggtgccatgg tgaaaatggc taaagactgg aaaaccgtgc ctgagagatt ccactgtgtg     1080

ggaggctccg tgcaggaccc tgagaaaata ccatccactg gcaagttggt gctgacactc     1140

acaaccgacg cctgtgaggg gaaggaaaat tttgtccgct acctggagca tgtccaggct     1200

gtcatcacgg tcaacgcaac cagaagagga gacctgaaca tcaacatgac ttcccctatg     1260

ggcaccaagt ccattttgct gagccggcgt ccaagggatg acgactccaa ggtgggcttt     1320

gacaagtggc ctttcatgac cactcacacg tggggggaag acgcccgagg cacctggacc     1380

ctggagctgg gatttgtcgg cagcgccccg cagaaggggg tgctgaagga gtggaccctg     1440

atgctgcatg gcactcagag tgccccgtac atcgaccagg tggtgcggga ttaccagtcc     1500

aagttggcca tgtccaagaa agaggagctg gaggaagagc tggacgaagc cgtggagaga     1560

agcctgaaaa gcatccttaa caagaac                                         1587


<210>  5204
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  5204
aaggatcccg cttttactgc tttgttaacc acccagttgc aagtgcaaag ggagattgta       60

aataaacaca atgaactaag gaaagcagtc tctccacctg ccagtaacat gctaaagatg      120

gaatggagca gagaggtaac aacgaatgcc caaaggtggg caaacaagtg cactttacaa      180

catagtgatc cagaggaccg caaaaccagt acaagatgtg gtgagaatct ctatatgtca      240

agtgacccta cttcctggtc ttctgcaatc caaagctggt atgacgagat cctagatttt      300

gtctatggtg taggaccaaa gagtcccaat gcagttgttg gacattatac tcagcttgtt      360

tggtactcga cttaccaggt aggctgtgga attgcctact gtcccaatca agatagtcta      420

aaatactact atgtttgcca atattgtcct gctggtaata atatgaatag aaagaatacc      480

ccgtaccaac aaggaacacc ttgtgccggt tgccctgatg actgtgacaa aggactatgc      540

accaatagtt gccagtatca agatctccta agtaactgtg attccttgaa gaatacagct      600

ggctgtgaac atgagttact caaggaaaag tgcaaggcta cttgcctatg tgagaacaaa      660

atttac                                                                 666


<210>  5205
<211>  1407
<212>  DNA
<213>  Homo Sapiens

<400>  5205
ggaaaggtgc tggtgtgggc agcagaatac agccattgga tgaatataaa gacaatcctg       60

gatgagctta ttcagagagg tcatgaggtg actgtactgg catcttcagc ttccattctt      120

tttgatccca acaactcatc cgctcttaaa attgaaattt atcccacatc tttaactaaa      180

actgagttgg agaatttcat catgcaacag attaagagat ggtcagacct tccaaaagat      240

acattttggt tatatttttc acaagtacag gaaatcatgt caatatttgg tgacataact      300

agaaagttct gtaaagatgt agtttcaaat aagaaattta tgaaaaaagt acaagagtca      360

agatttgacg tcatttttgc agatgctatt tttccctgta gtgagctgct ggctgagcta      420

tttaacatac cctttgtgta cagtctcagc ttctctcctg gctacacttt tgaaaagcat      480

agtggaggat ttattttccc tccttcctac gtacctgttg ttatgtcaga attaactgat      540

caaatgactt tcatggagag ggtaaaaaat atgatctatg tgctttactt tgacttttgg      600

ttcgaaatat ttgacatgaa gaagtgggat cagttttata gtgaagttct aggaagaccc      660

actacattat ctgagacaat ggggaaagct gacgtatggc ttattcgaaa ctcctggaat      720

tttcagtttc catatccact cttaccaaat gttgattttg ttggaggact ccactgcaaa      780

cctgccaaac ccctgcctaa ggaaatggaa gactttgtac agagctctgg agaaaatggt      840

gttgtggtgt tttctctggg gtcaatggtc agtaacatga cagaagaaag ggccaacgta      900

attgcatcag ccctggccca gatcccacaa aaggttctgt ggagatttga tgggaataaa      960

ccagatacct taggtctcaa tactcggctc tacaagtgga taccccagaa tgaccttcta     1020

ggtcatccaa agaccagagc ttttataact catggtggag ccaatggcat ctacgaggca     1080

atctaccatg ggatccctat ggtggggatt ccattgtttg ccgatcaacc tgataacatt     1140

gctcacatga aggccagggg agcagctgtt agagtggact tcaacacaat gtcgagtaca     1200

gacttgctga atgcattgaa gagagtaatt aatgatcctt catataaaga gaatgttatg     1260

aaattatcaa gaattcaaca tgatcaacca gtgaagcccc tggatcgagc agtcttctgg     1320

attgaatttg tcatgcgcca caaaggagct aaacaccttc gggttgcagc ccacgacctc     1380

acctggttcc agtaccactc tttggat                                         1407


<210>  5206
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  5206
ctgcagcaag aggacggcat ctccttcgag taccaccgct accccgagct gcgcgaggcg       60

ctcgtgtccg tgtggctgca gtgcaccgcc atcagcagga tttacacggt ggggcgcagc      120

ttcgagggcc gggagctcct ggtcatcgag ctgtccgaca accctggcgt ccatgagcct      180

ggtgagcctg aatttaaata cattgggaat atgcatggga atgaggctgt tggacgagaa      240

ctgctcattt tcttggccca gtacctatgc aacgaatacc agaaggggaa cgagacaatt      300

gtcaacctga tccacagtac ccgcattcac atcatgcctt ccctgaaccc agatggcttt      360

gagaaggcag cgtctcagcc tggtgaactc aaggactggt ttgtgggtcg aagcaatgcc      420

cagggaatag atctgaaccg gaactttcca gacctggata ggatagtgta cgtgaatgag      480

aaagaaggtg gtccaaataa tcatctgttg aaaaatatga agaaaattgt ggatcaaaac      540

acaaagcttg ctcctgagac caaggctgtc attcattgga ttatggatat tccttttgtg      600

ctttctgcca atctccatgg aggagacctt gtggccaatt atccatatga tgagacgcgg      660

agtggtagtg ctcatgaata cagctcctcc ccagatgacg ccattttcca aagcttggcc      720

cgggcatact cttctttcaa cccggccatg tctgacccca atcggccacc atgtcgcaag      780

aatgatgatg acagcagctt tgtagatgga accaccaacg gtggtgcttg gtacagcgta      840

cctggaggga tgcaagactt caattacctt agcagcaact gttttgagat caccgtggag      900

cttagctgtg agaagttccc acctgaagag actctgaaga cctactggga ggataacaaa      960

aactccctca ttagctacct tgagcagata caccgaggag ttaaaggatt tgtccgagac     1020

cttcaaggta acccaattgc gaatgccacc atctccgtgg aaggaataga ccacgatgtt     1080

acatccgcaa aggatggtga ttactggaga ttgcttatac ctggaaacta taaacttaca     1140

gcctcagctc caggctatct ggcaataaca aagaaagtgg cagttcctta cagccctgct     1200

gctggggttg attttgaact ggagtcattt tctgaaagga aagaagagga gaaggaagaa     1260

ttgatggaat ggtggaaaat gatgtcagaa actttaaatt tt                        1302


<210>  5207
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  5207
ctggacaatg ggctcctgca gacaccaccc atgggctggc tggcctggga acgcttccgc       60

tgcaacatta actgtgatga ggacccaaag aactgcataa gtgaacagct cttcatggag      120

atggctgacc ggatggcaca ggatggatgg cgggacatgg gctacacata cctcaacatt      180

gatgactgct ggatcggtgg tcgcgatgcc agtggccgcc tgatgccaga tcccaagcgc      240

ttccctcatg gcattccttt cctggctgac tacgttcact ccctgggcct gaagttgggt      300

atctacgcgg acatgggcaa cttcacctgc atgggttacc caggcaccac actggacaag      360

gtggtccagg atgctcagac cttcgccgag tggaaggtag acatgctcaa gctggatggc      420

tgcttctcca cccccgagga gcgggcccag gggtacccca agatggctgc tgccctgaat      480

gccacaggcc gccccatcgc cttctcctgc agctggccag cctatgaagg cggcctcccc      540

ccaagggtga actacagtct gctggcggac atctgcaacc tctggcgtaa ctatgatgac      600

atccaggact cctggtggag cgtgctctcc atcctgaatt ggttcgtgga gcaccaggac      660

atactgcagc cagtggccgg ccctgggcac tggaatgacc ctgacatgct gctcattggg      720

aactttggtc tcagcttaga gcaatcccgg gcccagatgg ccctgtggac ggtgctggca      780

gcccccctct tgatgtccac agacctgcgt accatctccg cccagaacat ggacattctg      840

cagaatccac tcatgatcaa aatcaaccag gatcccttag gcatccaggg acgcaggatt      900

cacaaggaaa aatctctcat cgaagtgtac atgcggcctc tgtccaacaa ggctagcgcc      960

ttagtcttct tcagctgcag gaccgatatg ccttatcgct accactcctc ccttggccag     1020

ctgaacttca ccgggtctgt gatatatgag gcccaggacg tctactcagg tgacatcatc     1080

agtggcctcc gagatgaaac caacttcaca gtgatcatca acccttcagg ggtagtgatg     1140

tggtacctgt atcccatcaa gaacctggag atgtcccagc ag                        1182


<210>  5208
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  5208
gtcaaccctg gcgtcgtggt caggatctcc cagaagggcc tggactacgc cagccagcag       60

gggacggccg ctctgcagaa ggagctgaag aggatcaaga ttcctgacta ctcagacagc      120

tttaagatca agcatcttgg gaaggggcat tatagcttct acagcatgga catccgtgaa      180

ttccagcttc ccagttccca gataagcatg gtgcccaatg tgggccttaa gttctccatc      240

agcaacgcca atatcaagat cagcgggaaa tggaaggcac aaaagagatt cttaaaaatg      300

agcggcaatt ttgacctgag catagaaggc atgtccattt cggctgatct gaagctgggc      360

agtaacccca cgtcaggcaa gcccaccatc acctgctcca gctgcagcag ccacatcaac      420

agtgtccacg tgcacatctc aaagagcaaa gtggggtggc tgatccaact cttccacaaa      480

aaaattgagt ctgcgcttcg aaacaagatg aacagccagg tctgcgagaa agtgaccaat      540

tctgtatcct ccaagctgca accttatttc cagactctgc cagtaatgac caaaatagat      600

tctgtggctg gaatcaacta tggtctggtg gcacctccag caaccacggc tgagaccctg      660

gatgtacaga tgaaggggga gttttacagt gagaaccacc acaatccacc tccctttgct      720

ccaccagtga tggagtttcc cgctgcccat gaccgcatgg tatacctggg cctctcagac      780

tacttcttca acacagccgg gcttgtatac caagaggctg gggtcttgaa gatgaccctt      840

agagatgaca tgattccaaa ggagtccaaa tttcgactga caaccaagtt ctttggaacc      900

ttcctacctg aggtggccaa gaagtttccc aacatgaaga tacagatcca tgtctcagcc      960

tccaccccgc cacacctgtc tgtgcagccc accggcctta ccttctaccc tgccgtggat     1020

gtccaggcct ttgccgtcct ccccaactcc tccctggctt ccctcttcct gattggcatg     1080

cacacaactg gttccatgga ggtcagcgcc gagtccaaca ggcttgttgg agagctcaag     1140

ctggataggc tgctcctgga actgaagcac tcaaatattg gccccttccc ggttgaattg     1200

ctgcaggata tcatgaacta cattgtaccc attcttgtgc tgcccagggt taacgagaaa     1260

ctacagaaag gcttccctct cccgacgccg gccagagtcc agctctacaa cgtagtgctt     1320

cagcctcacc agaacttcct gctgttcggt gcagacgttg tctataaa                  1368


<210>  5209
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  5209
acggatacag aggagcggct ggtggagcat ctcctggatc cttcccgcta caacaagctt       60

atccgcccag ccaccaatgg ctctgagctg gtgacagtac agcttatggt gtcactggcc      120

cagctcatca gtgtgcatga gcgggagcag atcatgacca ccaatgtctg gctgacccag      180

gagtgggaag attatcgcct cacctggaag cctgaagagt ttgacaacat gaagaaagtt      240

cggctccctt ccaaacacat ctggctccca gatgtggtcc tgtacaacaa tgctgacggc      300

atgtacgagg tgtccttcta ttccaatgcc gtggtctcct atgatggcag catcttctgg      360

ctgccgcctg ccatctacaa gagcgcatgc aagattgaag taaagcactt cccatttgac      420

cagcagaact gcaccatgaa gttccgttcg tggacctacg accgcacaga gatcgacttg      480

gtgctgaaga gtgaggtggc cagcctggac gacttcacac ctagtggtga gtgggacatc      540

gtggcgctgc cgggccggcg caacgagaac cccgacgact ctacgtacgt ggacatcacg      600

tatgacttca tcattcgccg caag                                             624


<210>  5210
<211>  1683
<212>  DNA
<213>  Homo Sapiens

<400>  5210
gaaacagtcc attgtgacct tcagcctgtg ggccccgaga gggacgaggt gacatatacc       60

actagccagg tctcgaaggg ctgcgtggct caggccccca atgccatcct tgaagtccat      120

gtcctcttcc tggagttccc aacgggcccg tcacagctgg agctgactct ccaggcatcc      180

aagcaaaatg gcacctggcc ccgagaggtg cttctggtcc tcagtgtaaa cagcagtgtc      240

ttcctgcatc tccaggccct gggaatccca ctgcacttgg cctacaattc cagcctggtc      300

accttccaag agcccccggg ggtcaacacc acagagctgc catccttccc caagacccag      360

atccttgagt gggcagctga gaggggcccc atcacctctg ctgctgagct gaatgacccc      420

cagagcatcc tcctccgact gggccaagcc caggggtcac tgtccttctg catgctggaa      480

gccagccagg acatgggccg cacgctcgag tggcggccgc gtactccagc cttggtccgg      540

ggctgccact tggaaggcgt ggccggccac aaggaggcgc acatcctgag ggtcctgccg      600

ggccactcgg ccgggccccg gacggtgacg gtgaaggtgg aactgagctg cgcacccggg      660

gatctcgatg ccgtcctcat cctgcagggt cccccctacg tgtcctggct catcgacgcc      720

aaccacaaca tgcagatctg gaccactgga gaatactcct tcaagatctt tccagagaaa      780

aacattcgtg gcttcaagct cccagacaca cctcaaggcc tcctggggga ggcccggatg      840

ctcaatgcca gcattgtggc atccttcgtg gagctaccgc tggccagcat tgtctcactt      900

catgcctcca gctgcggtgg taggctgcag acctcacccg caccgatcca gaccactcct      960

cccaaggaca cttgtagccc ggagctgctc atgtccttga tccagacaaa gtgtgccgac     1020

gacgccatga ccctggtact aaagaaagag cttgttgcgc atttgaagtg caccatcacg     1080

ggcctgacct tctgggaccc cagctgtgag gcagaggaca ggggtgacaa gtttgtcttg     1140

cgcagtgctt actccagctg tggcatgcag gtgtcagcaa gtatgatcag caatgaggcg     1200

gtggtcaata tcctgtcgag ctcatcacca cagcggaaaa aggtgcactg cctcaacatg     1260

gacagcctct ctttccagct gggcctctac ctcagcccac acttcctcca ggcctccaac     1320

accatcgagc cggggcagca gagctttgtg caggtcagag tgtccccatc cgtctccgag     1380

ttcctgctcc agttagacag ctgccacctg gacttggggc ctgagggagg caccgtggaa     1440

ctcatccagg gccgggcggc caagggcaac tgtgtgagcc tgctgtcccc aagccccgag     1500

ggtgacccgc gcttcagctt cctcctccac ttctacacag tacccatacc caaaaccggc     1560

accctcagct gcacggtagc cctgcgtccc aagaccgggt ctcaagacca ggaagtccat     1620

aggactgtct tcatgcgctt gaacatcatc agccctgacc tgtctggttg cacaagcaaa     1680

ggc                                                                   1683


<210>  5211
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5211
agtagctttt cctgggataa ctgtgatgaa gggaaggacc ctgcggtgat cagaagcctg       60

actctggagc ctgaccccat cgtcgttcct ggaaatgtga ccctcagtgt cgtgggcagc      120

accagtgtcc ccctgagttc tcctctgaag gtggatttag ttttggagaa ggaggtggct      180

ggcctctgga tcaagatccc atgcacagac tacattggca gctgtacctt tgaacacttc      240

tgtgatgtgc ttgacatgtt aattcctact ggggagccct gcccagagcc cctgcgtacc      300

tatgggcttc cttgccactg tcccttcaaa gaaggaacct actcactgcc caagagcgaa      360

ttcgttgtgc ctgacctgga gctgcccagt tggctcacca ccgggaacta ccgcatagag      420

agcgtcctga gcagcagtgg gaagcgtctg ggctgcatca agatcgctgc ctctctaaag      480

ggcata                                                                 486


<210>  5212
<211>  747
<212>  DNA
<213>  Homo Sapiens

<400>  5212
gcagacaatt tttcgctcca tgatgcgtta tctgggtctg gaaacccaaa ccctcaagga       60

tggcctggcg catgggggaa ccagcctgct ggggcagggg gctacccagg ggcttcctat      120

cctggggcct accccgggca ggcaccccca ggggcttatc ctggacaggc acctccaggc      180

gcctaccctg gagcacctgg agcttatccc ggagcacctg cacctggagt ctacccaggg      240

ccacccagcg gccctggggc ctacccatct tctggacagc caagtgccac cggagcctac      300

cctgccactg gcccctatgg cgcccctgct gggccactga ttgtgcctta taacctgcct      360

ttgcctgggg gagtggtgcc tcgcatgctg ataacaattc tgggcacggt gaagcccaat      420

gcaaacagaa ttgctttaga tttccaaaga gggaatgatg ttgccttcca ctttaaccca      480

cgcttcaatg agaacaacag gagagtcatt gtttgcaata caaagctgga taataactgg      540

ggaagggaag aaagacagtc ggttttccca tttgaaagtg ggaaaccatt caaaatacaa      600

gtactggttg aacctgacca cttcaaggtt gcagtgaatg atgctcactt gttgcagtac      660

aatcatcggg ttaaaaaact caatgaaatc agcaaactgg gaatttctgg tgacatagac      720

ctcaccagtg cttcatatac catgata                                          747


<210>  5213
<211>  792
<212>  DNA
<213>  Homo Sapiens

<400>  5213
ggcgcgagct cggggggctt gggtcccgtg gtgcgctgcg agccgtgcga cgcgcgtgca       60

ctggcccagt gcgcgcctcc gcccgccgtg tgcgcggagc tggtgcgcga gccgggctgc      120

ggctgctgcc tgacgtgcgc actgagcgag ggccagccgt gcggcatcta caccgagcgc      180

tgtggctccg gccttcgctg ccagccgtcg cccgacgagg cgcgaccgct gcaggcgctg      240

ctggacggcc gcgggctctg cgtcaacgct agtgccgtca gccgcctgcg cgcctacctg      300

ctgccagcgc cgccagctcc aggaaatgct agtgagtcgg aggaagaccg cagcgccggc      360

agtgtggaga gcccgtccgt ctccagcacg caccgggtgt ctgatcccaa gttccacccc      420

ctccattcaa agataatcat catcaagaaa gggcatgcta aagacagcca gcgctacaaa      480

gttgactacg agtctcagag cacagatacc cagaacttct cctccgagtc caagcgggag      540

acagaatatg gtccctgccg tagagaaatg gaagacacac tgaatcacct gaagttcctc      600

aatgtgctga gtcccagggg tgtacacatt cccaactgtg acaagaaggg attttataag      660

aaaaagcagt gtcgcccttc caaaggcagg aagcggggct tctgctggtg tgtggataag      720

tatgggcagc ctctcccagg ctacaccacc aaggggaagg aggacgtgca ctgctacagc      780

atgcagagca ag                                                          792


<210>  5214
<211>  870
<212>  DNA
<213>  Homo Sapiens

<400>  5214
gcggaggtgc tgttccgctg cccgccctgc acacccgagc gcctggccgc ctgcgggccc       60

ccgccggttg cgccgcccgc cgcggtggcc gcagtggccg gaggcgcccg catgccatgc      120

gcggagctcg tccgggagcc gggctgcggc tgctgctcgg tgtgcgcccg gctggagggc      180

gaggcgtgcg gcgtctacac cccgcgctgc ggccaggggc tgcgctgcta tccccacccg      240

ggctccgagc tgcccctgca ggcgctggtc atgggcgagg gcacttgtga gaagcgccgg      300

gacgccgagt atggcgccag cccggagcag gttgcagaca atggcgatga ccactcagaa      360

ggaggcctgg tggagaacca cgtggacagc accatgaaca tgttgggcgg gggaggcagt      420

gctggccgga agcccctcaa gtcgggtatg aaggagctgg ccgtgttccg ggagaaggtc      480

actgagcagc accggcagat gggcaagggt ggcaagcatc accttggcct ggaggagccc      540

aagaagctgc gaccaccccc tgccaggact ccctgccaac aggaactgga ccaggtcctg      600

gagcggatct ccaccatgcg ccttccggat gagcggggcc ctctggagca cctctactcc      660

ctgcacatcc ccaactgtga caagcatggc ctgtacaacc tcaaacagtg caagatgtct      720

ctgaacgggc agcgtgggga gtgctggtgt gtgaacccca acaccgggaa gctgatccag      780

ggagccccca ccatccgggg ggaccccgag tgtcatctct tctacaatga gcagcaggag      840

gctcgcgggg tgcacaccca gcggatgcag                                       870


<210>  5215
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5215
aacaatgcta ccacagttgc accttctgta ggaattacaa gattaattaa ctcatcaacg       60

gcagaaccag ttaaagaaga ggccaaaact tcaaatccaa cttcttcact aacttctctt      120

tctgtggcac caacattcag cccaaatata actctgggac ccacctattt aaccactgtc      180

aattcttcag actctgacaa tgggaccaca agaacagcaa gcaccaattc tataggcatt      240

acaatttcac caaatggaac gtggcttcca gataaccagt tcacggatgc cagaacagaa      300

ccctgggagg ggaattccag caccgcagca accactccag aaactttccc tccttcagat      360

gagacacca                                                              369


<210>  5216
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  5216
cacagcacca atgaacccag caacatgtca tacgtgaaag agacagtgga cagattgctc       60

aaaggatatg acattcgctt gcggccggac ttcggagggc cccccgtcga cgttgggatg      120

cggatcgatg tcgccagcat agacatggtc tccgaagtga atatggatta tacactcacc      180

atgtatttcc agcagtcttg gaaagacaaa aggctttctt attctggaat cccactgaac      240

ctcaccctag acaatagggt agctgaccaa ctctgtgtac cagacaccta ctttctgaat      300

gacaagaaat catttgtgca tggggtcaca gtgaaaaatc gaatgattcg actgcatcct      360

gatggaacag ttctctatgg actccgaatc acaaccacag ctgcatgtat gatggatctt      420

cgaagatatc cactggatga gcagaactgc accctggaga tcgaaagtta tggctatacc      480

actgatgaca ttgaatttta ctggaatgga ggagaagggg cagtcactgg tgttaataaa      540

atcgaacttc ctcaattttc aattgttgac tacaagatgg tgtctaagaa ggtggagttc      600

acaacaggag cgtatccacg actgtcacta agttttcgtc taaagagaaa cattggttac      660


<210>  5217
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5217
cagaaatctg atgatgacta tgaagattat gcttctaaca aaacatgggt cttgactcca       60

aaagttcctg agggtgatgt cactgtcatc ttaaacaacc tgctggaagg atatgacaat      120

aaacttcggc ctgatatagg agtgaagcca acgttaattc acacagacat gtatgtgaat      180

agcattggtc cagtgaacgc tatcaatatg gaatacacta ttgatatatt ttttgcgcaa      240

acgtggtatg acagacgttt gaaatttaac agcaccatta aagtcctccg attgaacagc      300

aacatggtgg ggaaaatctg gattccagac actttcttca gaaattccaa aaaagctgat      360

gcacactgga tcaccacccc caacaggatg ctgagaattt ggaatgatgg tcgagtgctc      420

tacaccctaa ggttgacaat tgatgctgag tgccaattac aattgcacaa ttttccaatg      480

gatgaacact cctgcccctt ggagttctcc agttatggct atccacgtga agaaattgtt      540

tatcaatgga agcgaagttc tgttgaagtg ggcgacacaa gatcctggag gctttatcaa      600

ttctcatttg ttggtctaag aaataccacc gaagtagtga agacaacttc cggagattat      660

gtggtcatgt ctgtctactt tgatctgagc agaagaatgg ga                         702


<210>  5218
<211>  144
<212>  DNA
<213>  Homo Sapiens

<400>  5218
gatgtcgccc acgggatcct taacgaggcc taccgcaaag tgctggacca gctgtccgcc       60

gggaagcacc tgcagtcgct cgtggcccgg ggcgtgggtg ggagcctcgg cggcggcgcg      120

ggggacgacg cggagccgct ctcc                                             144


<210>  5219
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  5219
gacaagctgc tggtggtccc tcaggacgga agccactggc ttagtatgaa ggatatagtt       60

gaggttctca gtgaccgggg tcatgagatt gtagtggtgg tgcctgaagt taatttgctt      120

ttgaaagaat ccaaatacta cacaagaaaa atctatccag tgccgtatga ccaagaagag      180

ctgaagaacc gttaccaatc atttggaaac aatcactttg ctgagcgatc attcctaact      240

gctcctcaga cagagtacag gaataacatg attgttattg gcctgtactt catcaactgc      300

cagagcctcc tgcaggacag ggacaccctg aacttcttta aggagagcaa gtttgatgct      360

cttttcacag acccagcctt accctgtggg gtgatcctgg ctgagtattt gggcctacca      420

tctgtgtacc tcttcagggg ttttccgtgt tccctggagc atacattcag cagaagccca      480

gaccctgtgt cctacattcc caggtgctac acaaagtttt cagaccacat gactttttcc      540

caacgagtgg ccaacttcct tgttaatttg ttggagccct atctatttta ttgtctgttt      600

tcaaagtatg aagaactcgc atcagctgtc ctcaagagag atgtggatat aatcacctta      660

tatcagaagg tctctgtttg gctgttaaga tatgactttg tgcttgaata tcctaggccg      720

gtcatgccca acatggtctt cattggaggt atcaactgta agaagaggaa agacttgtct      780

caggaatttg aagcctacat taatgcttct ggagaacatg gaattgtggt tttctctttg      840

ggatcaatgg tctcagaaat tccagagaag aaagctatgg caactgctga tgctttgggc      900

aaaatccctc agacagtcct gtggcggtac actggaaccc gaccatcgaa tcttgcgaac      960

aacacgatac ttgttaagtg gctaccccaa aacgatctgc ttggtcaccc gatgacccgt     1020

gcctttatca cccatgctgg ttcccatggt gtttatgaaa gcatatgcaa tggcgttccc     1080

atggtgatga tgcccttgtt tggtgatcag atggacaatg caaagcgcat ggagactaag     1140

ggagctggag tgaccctgaa tgttctggaa atgacttctg aagatttaga aaatgctcta     1200

aaagcagtca tcaatgacaa aagttacaag gagaacatca tgcgcctctc cagccttcac     1260

aaggaccgcc cggtggagcc gctggacctg gccgtgttct gggtggagtt tgtgatgagg     1320

cacaagggcg cgccacacct gcgccccgca gcccacgacc tcacctggta ccagtaccat     1380

tccttggac                                                             1389


<210>  5220
<211>  1629
<212>  DNA
<213>  Homo Sapiens

<400>  5220
ccctcagcct ccaaggaacc tgacaaccat gtgtacacca gggctgccgt ggccgcggat       60

gccaagcagt gctcgaagat tgggagggat gcactgcggg acggtggctc tgcggtggat      120

gcagccattg cagccctgtt gtgtgtgggg ctcatgaatg cccacagcat gggcatcggg      180

ggtggcctct tcctcaccat ctacaacagc accacacgaa aagctgaggt catcaacgcc      240

cgcgaggtgg cccccaggct ggcctttgcc accatgttca acagctcgga gcagtcccag      300

aagggggggc tgtcggtggc ggtgcctggg gagatccgag gctatgagct ggcacaccag      360

cggcatgggc ggctgccctg ggctcgcctc ttccagccca gcatccagct ggcccgccag      420

ggcttccccg tgggcaaggg cttggcggca gccctggaaa acaagcggac cgtcatcgag      480

cagcagcctg tcttgtgtga ggtgttctgc cgggatagaa aggtgcttcg ggagggggag      540

agactgaccc tgccgcagct ggctgacacc tacgagacgc tggccatcga gggtgcccag      600

gccttctaca acggcagcct cacggcccag attgtgaagg acatccaggc ggccgggggc      660

attgtgacag ctgaggacct gaacaactac cgtgctgagc tgatcgagca cccgctgaac      720

atcagcctgg gagacgtggt gctgtacatg cccagtgcgc cgctcagcgg gcccgtgctg      780

gccctcatcc tcaacatcct caaagggtac aacttctccc gggagagcgt ggagagcccc      840

gagcagaagg gcctgacgta ccaccgcatc gtagaggctt tccggtttgc ctacgccaag      900

aggaccctgc ttggggaccc caagtttgtg gatgtgactg aggtggtccg caacatgacc      960

tccgagttct tcgctgccca gctccgggcc cagatctctg acgacaccac tcacccgatc     1020

tcctactaca agcccgagtt ctacacgccg gatgacgggg gcactgctca cctgtctgtc     1080

gtcgcagagg acggcagtgc tgtgtccgcc accagcacca tcaacctcta ctttggctcc     1140

aaggtccgct ccccggtcag cgggatcctg ttcaataatg aaatggacga cttcagctct     1200

cccagcatca ccaacgagtt tggggtaccc ccctcacctg ccaatttcat ccagccaggg     1260

aagcagccgc tctcgtccat gtgcccgacg atcatggtgg gccaggacgg ccaggtccgg     1320

atggtggtgg gagctgctgg gggcacacag atcaccacgg ccactgcact ggccatcatc     1380

tacaacctct ggttcggcta tgacgtgaag cgggccgtgg aggagccccg gctgcacaac     1440

cagcttctgc ccaacgtcac gacagtggag agaaacattg accaggcagt gactgcagcc     1500

ctggagaccc ggcaccatca cacccagatc gcgtccacct tcatcgctgt ggtgcaagcc     1560

atcgtccgca cggctggtgg ctgggcagct gcctcggact ccaggaaagg cggggagcct     1620

gccggctac                                                             1629


<210>  5221
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5221
cagatcccat tgtgtgccaa cctagtaccg gtgcccatca ccaacgccac cctggaccgg       60

atcactggca agtggtttta tatcgcatcg gcctttcgaa acgaggagta caataagtcg      120

gttcaggaga tccaagcaac cttcttttac tttaccccca acaagacaga ggacacgatc      180

tttctcagag agtaccagac ccgccagaac cagtgcttct ataactccag ttacctgaat      240

gtccagcggg agaatgggac cgtctccaga tacgagggag gccgagaaca tgttgctcac      300

ctgctgttcc ttagggacac caagaccttg atgtttggtt cctacctgga cgatgagaag      360

aactgggggc tgtctttcta tgctgacaag ccagagacga ccaaggagca actgggagag      420

ttctacgaag ctctcgactg cttgtgcatt cccaggtcag atgtcatgta caccgactgg      480

aaaaaggata agtgtgagcc actggagaag cagcacgaga aggagaggaa acaggaggag      540

ggggaatcc                                                              549


<210>  5222
<211>  945
<212>  DNA
<213>  Homo Sapiens

<400>  5222
gggaactgct ggctccgtca agcgaagaac ggccgctgcc aggtcctgta caagaccgaa       60

ctgagcaagg aggagtgctg cagcaccggc cggctgagca cctcgtggac cgaggaggac      120

gtgaatgaca acacactctt caagtggatg attttcaacg ggggcgcccc caactgcatc      180

ccctgtaaag aaacgtgtga gaacgtggac tgtggacctg ggaaaaaatg ccgaatgaac      240

aagaagaaca aaccccgctg cgtctgcgcc ccggattgtt ccaacatcac ctggaagggt      300

ccagtctgcg ggctggatgg gaaaacctac cgcaatgaat gtgcactcct aaaggcaaga      360

tgtaaagagc agccagaact ggaagtccag taccaaggca gatgtaaaaa gacttgtcgg      420

gatgttttct gtccaggcag ctccacatgt gtggtggacc agaccaataa tgcctactgt      480

gtgacctgta atcggatttg cccagagcct gcttcctctg agcaatatct ctgtgggaat      540

gatggagtca cctactccag tgcctgccac ctgagaaagg ctacctgcct gctgggcaga      600

tctattggat tagcctatga gggaaagtgt atcaaagcaa agtcctgtga agatatccag      660

tgcactggtg ggaaaaaatg tttatgggat ttcaaggttg ggagaggccg gtgttccctc      720

tgtgatgagc tgtgccctga cagtaagtcg gatgagcctg tctgtgccag tgacaatgcc      780

acttatgcca gcgagtgtgc catgaaggaa gctgcctgct cctcaggtgt gctactggaa      840

gtaaagcact ccggatcttg caactccatt tcggaagaca ccgaggaaga ggaggaagat      900

gaagaccagg actacagctt tcctatatct tctattctag agtgg                      945


<210>  5223
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5223
gcgcaagagc cagtcaaagg tccagtctcc actaagcctg gctcctgccc cattatcttg       60

atccggtgcg ccatgttgaa tccccctaac cgctgcttga aagatactga ctgcccagga      120

atcaagaagt gctgtgaagg ctcttgcggg atggcctgtt tcgttcccca g               171


<210>  5224
<211>  3030
<212>  DNA
<213>  Homo Sapiens

<400>  5224
atttcttgtg gctctcctcc gcctatccta aatggccgga ttagttatta ttctaccccc       60

attgctgttg gtaccgtgat aaggtacagt tgttcaggta ccttccgcct cattggagaa      120

aaaagtctat tatgcataac taaagacaaa gtggatggaa cctgggataa acctgctcct      180

aaatgtgaat atttcaataa atattcttct tgccctgagc ccatagtacc aggaggatac      240

aaaattagag gctctacacc ctacagacat ggtgattctg tgacatttgc ctgtaaaacc      300

aacttctcca tgaacggaaa caagtctgtt tggtgtcaag caaataatat gtgggggccg      360

acacgactac caacctgtgt aagtgttttc cctctcgagt gtccagcact tcctatgatc      420

cacaatggac atcacacaag tgagaatgtt ggctccattg ctccaggatt gtctgtgact      480

tacagctgtg aatctggtta cttgcttgtt ggagaaaaga tcattaactg tttgtcttcg      540

ggaaaatgga gtgctgtccc ccccacatgt gaagaggcac gctgtaaatc tctaggacga      600

tttcccaatg ggaaggtaaa ggagcctcca attctccggg ttggtgtaac tgcaaacttt      660

ttctgtgatg aagggtatcg actgcaaggc ccaccttcta gtcggtgtgt aattgctgga      720

cagggagttg cttggaccaa aatgccagta tgtgaagaaa ttttttgccc atcacctccc      780

cctattctca atggaagaca tataggcaac tcactagcaa atgtctcata tggaagcata      840

gtcacttaca cttgtgaccc ggacccagag gaaggagtga acttcatcct tattggagag      900

agcactctcc gttgtacagt tgatagtcag aagactggga cctggagtgg ccctgcccca      960

cgctgtgaac tttctacttc tgcggttcag tgtccacatc cccagatcct aagaggccga     1020

atggtatctg ggcagaaaga tcgatatacc tataacgaca ctgtgatatt tgcttgcatg     1080

tttggcttca ccttgaaggg cagcaagcaa atccgatgca atgcccaagg cacatgggag     1140

ccatctgcac cagtctgtga aaaggaatgc caggcccctc ctaacatcct caatgggcaa     1200

aaggaagata gacacatggt ccgctttgac cctggaacat ctataaaata tagctgtaac     1260

cctggctatg tgctggtggg agaagaatcc atacagtgta cctctgaggg ggtgtggaca     1320

ccccctgtac cccaatgcaa agtggcagcg tgtgaagcta caggaaggca actcttgaca     1380

aaaccccagc accaatttgt tagaccagat gtcaactctt cttgtggtga agggtacaag     1440

ttaagtggga gtgtttatca ggagtgtcaa ggcacaattc cttggtttat ggagattcgt     1500

ctttgtaaag aaatcacctg cccaccaccc cctgttatct acaatggggc acacaccggg     1560

agttccttag aagattttcc atatggaacc acggtcactt acacatgtaa ccctgggcca     1620

gaaagaggag tggaattcag cctcattgga gagagcacca tccgttgtac aagcaatgat     1680

caagaaagag gcacctggag tggccctgct cccctgtgta aactttccct ccttgctgtc     1740

cagtgctcac atgtccatat tgcaaatgga tacaagatat ctggcaagga agccccatat     1800

ttctacaatg acactgtgac attcaagtgt tatagtggat ttactttgaa gggcagtagt     1860

cagattcgtt gcaaagctga taacacctgg gatcctgaaa taccagtttg tgaaaaaggc     1920

tgccagtcac ctcctgggct ccaccatggt cgtcatacag gtggaaatac ggtcttcttt     1980

gtctctggga tgactgtaga ctacacttgt gaccctggct atttgcttgt gggaaacaaa     2040

tccattcact gtatgccttc aggaaattgg agtccttctg ccccacggtg tgaagaaaca     2100

tgccagcatg tgagacagag tcttcaagaa cttccagctg gttcacgtgt ggagctagtt     2160

aatacgtcct gccaagatgg gtaccagttg actggacatg cttatcagat gtgtcaagat     2220

gctgaaaatg gaatttggtt caaaaagatt ccactttgta aagttattca ctgtcaccct     2280

ccaccagtga ttgtcaatgg gaagcacaca ggcatgatgg cagaaaactt tctatatgga     2340

aatgaagtct cttatgaatg tgaccaagga ttctatctcc tgggagagaa aaaattgcag     2400

tgcagaagtg attctaaagg acatggatct tggagcgggc cttccccaca gtgcttacga     2460

tctcctcctg tgactcgctg ccctaatcca gaagtcaaac atgggtacaa gctcaataaa     2520

acacattctg catattccca caatgacata gtgtatgttg actgcaatcc tggcttcatc     2580

atgaatggta gtcgcgtgat taggtgtcat actgataaca catgggtgcc aggtgtgcca     2640

acttgtatca aaaaagcctt catagggtgt ccacctccgc ctaagacccc taacgggaac     2700

catactggtg gaaacatagc tcgattttct cctggaatgt caatcctgta cagctgtgac     2760

caaggctacc tgctggtggg agaggcactc cttctttgca cacatgaggg aacctggagc     2820

caacctgccc ctcattgtaa agaggtaaac tgtagctcac cagcagatat ggatggaatc     2880

cagaaagggc tggaaccaag gaaaatgtat cagtatggag ctgttgtaac tctggagtgt     2940

gaagatgggt atatgctgga aggcagtccc cagagccagt gccaatcgga tcaccaatgg     3000

aaccctcccc tggcggtttg cagatcccgt                                      3030


<210>  5225
<211>  1230
<212>  DNA
<213>  Homo Sapiens

<400>  5225
gagatttgtg aggtaagtga agaaaactac atccgcctaa aacctctgtt gaatacaatg       60

atccagtcaa actataacag gggaaccagc gctgtcaatg ttgtgttgtc cctcaaactt      120

gttggaatcc agatccaaac cctgatgcaa aagatgatcc aacaaatcaa atacaatgtg      180

aaaagcagat tgtcagatgt aagctcggga gagcttgcct tgattatact ggctttggga      240

gtatgtcgta acgctgagga aaacttaata tatgattacc acctgatcga caagctagaa      300

aataaattcc aagcagaaat tgaaaatatg gaagcacaca atggcactcc cctgactaac      360

tactaccagc tcagcctgga cgttttggcc ttgtgtctgt tcaatgggaa ctactcaacc      420

gccgaagttg tcaaccactt cactcctgaa aataaaaact attattttgg tagccagttc      480

tcagtagata ctggtgcaat ggctgtcctg gctctgacct gtgtgaagaa gagtctaata      540

aatgggcaga tcaaagcaga tgaaggcagt ttaaagaaca tcagtattta tacaaagtca      600

ctggtagaaa agattctgtc tgagaaaaaa gaaaatggtc tcattggaaa cacatttagc      660

acaggagaag ccatgcaggc cctctttgta tcatcagact attataatga aaatgactgg      720

aattgccaac aaactctgaa tacagtgctc acggaaattt ctcaaggagc attcagcaat      780

ccaaacgctg cagcccaggt cttacctgcc ctgatgggaa agaccttctt ggatattaac      840

aaagactctt cttgcgtctc tgcttcaggt aacttcaaca tctccgctga tgagcctata      900

actgtgacac ctcctgactc acaatcatat atctccgtca attactctgt gagaatcaat      960

gaaacatatt tcaccaatgt cactgtgcta aatggttctg tcttcctcag tgtgatggag     1020

aaagcccaga aaatgaatga tactatattt ggtttcacaa tggaggagcg ctcatggggg     1080

ccctatatca cctgtattca gggcctatgt gccaacaata atgacagaac ctactgggaa     1140

cttctgagtg gaggcgaacc actgagccaa ggagctggta gttacgttgt ccgcaatgga     1200

gaaaacttgg aggttcgctg gagcaaatac                                      1230


<210>  5226
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  5226
gagatgtgtg aaataccaga gatggacagc catctggtag agaagttggg ccagcacctc       60

ttaccttgga tggaccggct ttccctggag cacttgaacc ccagcatcta tgtgggccta      120

cgcctctcca gtctgcaggc tgggaccaag gaagacctct acctgcacag cctcaagctt      180

ggttaccagc agtgcctcct agggtctgcc ttcagcgagg atgacggtga ctgccagggc      240

aagccttcca tgggccagct ggccctctac ctgctcgctc tcagagccaa ctgtgagttt      300

gtcaggggcc acaaggggga caggctggtc tcacagctca aatggttcct ggaggatgag      360

aagagagcca ttgggcatga tcacaagggc cacccccaca ctagctacta ccagtatggc      420

ctgggcattc tggccctgtg tctccaccag aagcgggtcc atgacagcgt ggtggacaaa      480

cttctgtatg ctgtggaacc tttccaccag ggccaccatt ctgtggacac agcagccatg      540

gcaggcttgg cattcacctg tctgaagcgc tcaaacttca accctggtcg gagacaacgg      600

atcaccatgg ccatcagaac agtgcaagag gagatcttga aggcccagac ccccgagggc      660

cactttggga atgtctacag caccccattg gcattacagt tcctcatgac ttcccccatg      720

cgtggggcag aactgggaac agcatgtctc aaggcgaggg ttgctttgct ggccagtctg      780

caggatggag ccttccagaa tgctctcatg atttcccagc tgctgcccgt tctgaaccac      840

aagacctaca ttgatctgat cttcccagac tgtctggcac cacgagtcat gttggaacca      900

gctgctgaga ccattcctca gacccaagag atcatcagtg tcacgctgca ggtgcttagt      960

ctcttgccgc cgtacagaca gtccatctct gttctggccg ggtccaccgt ggaagatgtc     1020

ctgaagaagg cccatgagtt aggaggattc acatatgaaa cacaggcctc cttgtcaggc     1080

ccctacttaa cctccgtgat ggggaaagcg gccggagaaa gggagttctg gcagcttctc     1140

cgagacccca acaccccact gttgcaaggt attgctgact acagacccaa ggatggagaa     1200

accattgagc tgaggctggt tagctgg                                         1227


<210>  5227
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  5227
attgtgggag gctgggagtg tgagaagcat tcccaaccct ggcaggtggc tgtgtacagt       60

catggatggg cacactgtgg gggtgtcctg gtgcaccccc agtgggtgct cacagctgcc      120

cattgcctaa agaagaatag ccaggtctgg ctgggtcggc acaacctgtt tgagcctgaa      180

gacacaggcc agagggtccc tgtcagccac agcttcccac acccgctcta caatatgagc      240

cttctgaagc atcaaagcct tagaccagat gaagactcca gccatgacct catgctgctt      300

cgcctgtcag agcctgccaa gatcacagat gttgtgaagg tcctgggcct gcccacccag      360

gagccagcac tggggaccac ctgctacgcc tcaggctggg gcagcatcga accagaggag      420

ttcttgcgcc ccaggagtct tcagtgtgtg agcctccatc tcctgtccaa tgacatgtgt      480

gctagagctt actctgagaa ggtgacagag ttcatgttgt gtgctgggct ctggacaggt      540

ggtaaagaca cttgtggggg tgattctggg ggtccacttg tctgtaatgg tgtgcttcaa      600

ggtatcacat catggggccc tgagccatgt gccctgcctg aaaagcctgc tgtgtacacc      660

aaggtggtgc attaccggaa gtggatcaag gacaccatcg cagccaaccc c               711


<210>  5228
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  5228
atcgttggcg gccggaaggc gaggccccgc cagttcccgt tcctggcctc cattcagaat       60

caaggcaggc acttctgcgg gggtgccctg atccatgccc gcttcgtgat gaccgcggcc      120

agctgcttcc aaagccagaa ccccggggtt agcaccgtgg tgctgggtgc ctatgacctg      180

aggcggcggg agaggcagtc ccgccagacg ttttccatca gcagcatgag cgagaatggc      240

tacgaccccc agcagaacct gaacgacctg atgctgcttc agctggaccg tgaggccaac      300

ctcaccagca gcgtgacgat actgccactg cctctgcaga acgccacggt ggaagccggc      360

accagatgcc aggtggccgg ctgggggagc cagcgcagtg gggggcgtct ctcccgtttt      420

cccaggtttg tcaacgtgac tgtgaccccc gaggaccagt gtcgccccaa caacgtgtgc      480

accggtgtgc tcacccgccg cggtggcatc tgcaatgggg acgggggcac ccccctcgtc      540

tgcgagggcc tggcccacgg cgtggcctcc ttttccctgg ggccctgtgg ccgaggccct      600

gacttcttca cccgagtggc gctcttccga gactggatcg atggtgttct caacaacccg      660

ggaccg                                                                 666


<210>  5229
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  5229
atcgtcgggg gtcaggaggc ccccaggagc aagtggccct ggcaggtgag cctgagagtc       60

cgcgaccgat actggatgca cttctgtggg ggctccctca tccaccccca gtgggtgctg      120

accgcggcgc actgcctggg accggacgtc aaggatctgg ccaccctcag ggtgcaactg      180

cgggagcagc acctctacta ccaggaccag ctgctgccgg tcagcaggat catcgtgcac      240

ccacagttct acatcatcca gactggagcg gatatcgccc tgctggagct ggaggagccc      300

gtgaacatct ccagccgcgt ccacacggtc atgctgcccc ctgcctcgga gaccttcccc      360

ccggggatgc cgtgctgggt cactggctgg ggcgatgtgg acaatgatga gcccctccca      420

ccgccatttc ccctgaagca ggtgaaggtc cccataatgg aaaaccacat ttgtgacgca      480

aaataccacc ttggcgccta cacgggagac gacgtccgca tcatccgtga cgacatgctg      540

tgtgccggga acacccggag ggactcatgc cagggcgact ctggagggcc cctggtgtgc      600

aaggtgaatg gcacctggct acaggcgggc gtggtcagct gggacgaggg ctgtgcccag      660

cccaaccggc ctggcatcta cacccgtgtc acctactact tggactggat ccaccactat      720

gtccccaaaa agccg                                                       735


<210>  5230
<211>  432
<212>  DNA
<213>  Homo Sapiens

<400>  5230
attttacttt cagcatccaa gtccataaga aatttagatg atgacatggt atttaataca       60

ttcaggttgg ggaaaggctt tcagaaggaa gacactgcag aaaaatcagt tattgctcct      120

tccctggaac aatataaaaa tgatgagagc agtttcatga acgaagagga aaataaagtt      180

tcaaagaaca caggctccaa acataatttc ttaaatcatg gtctgccact gaatctggct      240

ataaaacctt atcttgcact aaaaggatct gtagctttcc cagctgagaa tggagttcag      300

aatactgaat caacacaaga aaagagagaa attggggatg aagaaaactc agctaaattt      360

cctataggaa ggagagattt tgacatgctc agatgtatgc tgggaagagt ctaccgacct      420

tgttggcaag tc                                                          432


<210>  5231
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  5231
cagccagagg cggcccagca ggaggcagtg acggccgcgg agcatccggg cctggatgac       60

ttcctgcgcc aggtggagcg cctcctcttc ctccgggaaa acatccagcg gctgcaaggg      120

gaccagggtg agcactccgc gtcccagatc tttcaatctg actggctctc caaacgtcag      180

catccaggca aaagagagga ggaggaggaa gagggagttg aagaagagga agaggaagaa      240

gggggggctg tgggacccca caaacggcag caccctggcc gacgagaaga tgaggcttca      300

tggtcagtcg atgtaaccca gcacaagcgg cagcatcctg gccggcgctc cccctggctt      360

gcatatgctg tcccgaagcg gcagcaccca ggcagaaggc tggcagatcc caaggctcaa      420

aggagctggg aagaagagga ggaggaggaa gagagagagg aagacctgat gcctgaaaaa      480

cgccagcatc cgggcaagag ggccctggga ggcccctgtg ggccccaggg agcctatggt      540

caagcgggcc tcctgctggg gctcctggat gacctgagta ggagccaggg agctgaggaa      600

aagcggcagc accctggtcg gcgggcagcc tgggtcaggg agcccctgga ggag            654


<210>  5232
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  5232
atcatcgggg gccatgaggc caagccccac tcccgcccct acatggcctt tgttcagttt       60

ctgcaagaga agagtcggaa gaggtgtggc ggcatcctag tgagaaagga ctttgtgctg      120

acagctgctc actgccaggg aagctccata aatgtcacct tgggggccca caatatcaag      180

gaacaggagc ggacccagca gtttatccct gtgaaaagac ccatccccca tccagcctat      240

aatcctaaga acttctccaa cgacatcatg ctactgcagc tggagagaaa ggccaagtgg      300

accacagctg tgcggcctct caggctacct agcagcaagg cccaggtgaa gccagggcag      360

ctgtgcagtg tggctggctg gggttatgtc tcaatgagca ctttagcaac cacactgcag      420

gaagtgttgc tgacagtgca gaaggactgc cagtgtgaac gtctcttcca tggcaattac      480

agcagagcca ctgagatttg tgtgggggat ccaaagaaga cacagaccgg tttcaagggg      540

gactccgggg ggcccctcgt gtgtaaggac gtagcccaag gtattctctc ctatggaaac      600

aaaaaaggga cacctccagg agtctacatc aaggtctcac acttcctgcc ctggataaag      660

agaacaatga agcgcctc                                                    678


<210>  5233
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5233
tcagatgagc actgtccaga gcttcctcca gtggacaata gcatatttgt cgcaaaggag       60

gtggaaggac agattctggg gacttacgtt tgtatcaagg gctaccacct ggtaggaaag      120

aagacccttt tttgcaatgc ctctaaggag tgggataaca ccactactga gtgccgcttg      180

ggccactgtc ctgatcctgt gctggtgaat ggagagttca gttcttcagg gcctgtgaat      240

gtaagtgaca aaatcacgtt tatgtgcaat gaccactaca tcctcaaggg cagcaatcgg      300

agccagtgtc tagaggacca cacctgggca cctccctttc ccatctgcaa aagtagggac      360

tgtgaccctc ctgggaatcc agttcatggc tattttgaag gaaataactt caccttagga      420

tccaccatta gttattactg tgaagacagg tactacttag tgggcgtgca ggagcagcaa      480

tgcgttgatg gggagtggag cagtgcactt ccagtctgca agttgatcca ggaagctccc      540

aaaccagagt gtgagaaggc acttcttgcc tttcaggaga gtaagaacct ctgcgaagcc      600

atggagaact ttatgcaaca attaaaggaa agtggcatga caatggagga gctaaaatat      660

tctctggagc tgaagaaagc tgagttgaag gcaaaattgt tg                         702


<210>  5234
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  5234
tccagccctc tgcccctggt cgtcaacact tggcccttta agaatgcaac cgaagcagcg       60

tggagggcat tagcatctgg aggctctgcc ctggatgcag tggagagcgg ctgtgccatg      120

tgtgagagag agcagtgtga cggctctgta ggctttggag gaagtcctga tgaacttgga      180

gaaaccacac tagatgccat gatcatggat ggcactacta tggatgtagg agcagtagga      240

gatctcagac gaattaaaaa tgctattggt gtggcacgga aagtactgga acatacaaca      300

cacacacttt tagtaggaga gtcagccacc acatttgctc aaagtatggg gtttatcaat      360

gaagacttat ctaccagtgc ttctcaagct cttcattcag attggcttgc tcggaattgc      420

cagccaaatt attggaggaa cgttatacca gatccctcaa aatactgcgg accctacaaa      480

ccacctggta tcttaaagca ggatattcct atccataaag aaacagaaga tgatcgtggt      540

catgacacta ttggcatggt tgtaatccat aagacaggac atattgctgc tggtacatct      600

acaaatggta taaaattcaa aatacatggc cgtgtaggag actcaccaat acctggagct      660

ggagcctatg ctgacgatac tgcaggggca gccgcagcca ctgggaatgg tgatatattg      720

atgcgcttcc tgccaagcta ccaagctgta gaatacatga gaagaggaga agatccaacc      780

atagcttgcc aaaaagtgat ttcaagaatc cagaagcatt ttccagaatt ctttggggct      840

gttatatgtg ccaatgtgac tggaagttac ggtgctgctt gcaataaact ttcaacattt      900

actcagttta gtttcatggt ttataattcc gaaaaaaatc agccaactga ggaaaaagtg      960

gactgcatc                                                              969


<210>  5235
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  5235
gggaagaaag agaaaccaga aaaaaaagtg aagaagtctg actgtggaga atggcagtgg       60

agtgtgtgtg tgcccaccag tggagactgt gggctgggca cacgggaggg cactcggact      120

ggagctgagt gcaagcaaac catgaagacc cagagatgta agatcccctg caactggaag      180

aagcaatttg gcgcggagtg caaataccag ttccaggcct ggggagaatg tgacctgaac      240

acagccctga agaccagaac tggaagtctg aagcgagccc tgcacaatgc cgaatgccag      300

aagactgtca ccatctccaa gccctgtggc aaactgacca agcccaaacc tcaagcagaa      360

tctaagaaga agaaaaagga aggcaagaaa caggagaaga tgctggat                   408


<210>  5236
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5236
gtcgccaaaa agaaagataa ggtgaagaag ggcggcccgg ggagcgagtg cgctgagtgg       60

gcctgggggc cctgcacccc cagcagcaag gattgcggcg tgggtttccg cgagggcacc      120

tgcggggccc agacccagcg catccggtgc agggtgccct gcaactggaa gaaggagttt      180

ggagccgact gcaagtacaa gtttgagaac tggggtgcgt gtgatggggg cacaggcacc      240

aaagtccgcc aaggcaccct gaagaaggcg cgctacaatg ctcagtgcca ggagaccatc      300

cgcgtcacca agccctgcac ccccaagacc aaagcaaagg ccaaagccaa gaaagggaag      360

ggaaaggac                                                              369


<210>  5237
<211>  903
<212>  DNA
<213>  Homo Sapiens

<400>  5237
ttctcaatga aaaatttgca tcgaagagtc aaaatagagg attctgaaga aaatggggtc       60

tttaagtaca ggccacgata ttatctttac aagcatgcct acttttatcc tcatttaaaa      120

cgatttccag ttcagggcag tagtgactca tccgaagaaa atggagatga cagttcagaa      180

gaggaggagg aagaagagga gacttcaaat gaaggagaaa acaatgaaga atcgaatgaa      240

gatgaagact ctgaggctga gaataccaca ctttctgcta caacactggg ctatggagag      300

gacgccacgc ctggcacagg gtatacaggg ttagctgcaa tccagcttcc caagaaggct      360

ggggatataa caaataaagc tacaaaagag aaggaaagtg atgaagaaga agaggaggaa      420

gaggaaggaa atgaaaacga agaaagcgaa gcagaagtgg atgaaaacga acaaggcata      480

aacggcacca gtaccaacag cacagaggca gaaaacggca acggcagcag cggaggagac      540

aatggagaag aaggggaaga agaaagtgtc actggagcca atgcagaaga caccacagag      600

accggaaggc agggcaaggg cacctcgaag acaacaacct ctccaaatgg tgggtttgaa      660

cctacaaccc caccacaagt ctatagaacc acttccccac cttttgggaa aaccaccacc      720

gttgaatacg agggggagta cgaatacacg ggcgccaatg aatacgacaa tggatatgaa      780

atctatgaaa gtgagaacgg ggaacctcgt ggggacaatt accgagccta tgaagatgag      840

tacagctact ttaaaggaca aggctacgat ggctatgatg gtcagaatta ctaccaccac      900

cag                                                                    903


<210>  5238
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  5238
aggcactggg gctggggcct gtgccttatc ggctggaacg agttcatcct gcagcccatc       60

cacaacctgc tcatgggtga caccaaggag cagcgcatcc tgaaccacgt gctgcagcat      120

gcggagcccg ggaacgcaca gagcgtgctg gaggccattg acacctactg cgagcagaag      180

gagtgggcca tgaacgtggg cgacaagaaa ggcaagatcg tggacgccgt gattcaggag      240

caccagccct ccgtgctgct ggagctgggg gcctactgtg gctactcagc tgtgcgcatg      300

gcccgcctgc tgtcaccagg ggcgaggctg atcaccatcg agatcaaccc cgactgtgcc      360

gccatcaccc agcggatggt ggatttcgct ggcgtgaagg acaaggtcac ccttgtggtt      420

ggagcgtccc aggacatcat cccccagctg aagaagaagt atgatgtgga cacactggac      480

atggtcttcc tcgaccactg gaaggaccgg tacctgccgg acacgcttct cttggaggaa      540

tgtggcctgc tgcggaaggg gacagtgcta ctggctgaca acgtgatctg cccaggtgcg      600

ccagacttcc tagcacacgt gcgcgggagc agctgctttg agtgcacaca ctaccaatcg      660

ttcctggaat acagggaggt ggtggacggc ctggagaagg ccatctacaa gggcccaggc      720

agcgaagcag ggccc                                                       735


<210>  5239
<211>  1395
<212>  DNA
<213>  Homo Sapiens

<400>  5239
catgctggga agatactgtt gatcccagtg gatggcagcc actggctgag catgcttggg       60

gccatccagc agctgcagca gaggggacat gaaatagttg tcctagcacc tgacgcctcg      120

ttgtacatca gagacggagc attttacacc ttgaagacgt accctgtgcc attccaaagg      180

gaggatgtga aagagtcttt tgttagtctc gggcataatg tttttgagaa tgattctttc      240

ctgcagcgtg tgatcaaaac atacaagaaa ataaaaaagg actctgctat gcttttgtct      300

ggctgttccc acttactgca caacaaggag ctcatggcct ccctggcaga aagcagcttt      360

gatgtcatgc tgacggaccc tttccttcct tgcagcccca tcgtggccca gtacctgtct      420

ctgcccactg tattcttctt gcatgcactg ccatgcagcc tggaatttga ggctacccag      480

tgccccaacc cattctccta cgtgcccagg cctctctcct ctcattcaga tcacatgacc      540

ttcctgcagc gggtgaagaa catgctcatt gccttttcac agaactttct gtgcgacgtg      600

gtttattccc cgtatgcaac ccttgcctca gaattccttc agagagaggt gactgtccag      660

gacctattga gctctgcatc tgtctggctg tttagaagtg actttgtgaa ggattaccct      720

aggcccatca tgcccaatat ggtttttgtt ggtggaatca actgccttca ccaaaatcca      780

ctatcccagg aatttgaagc ctacattaat gcttctggag aacatggaat tgtggttttc      840

tctttgggat caatggtctc agaaattcca gagaagaaag ctatggcaat tgctgatgct      900

ttgggcaaaa tccctcagac agtcctgtgg cggtacactg gaacccgacc atcgaatctt      960

gcgaacaaca cgatacttgt taagtggcta ccccaaaacg atctgcttgg tcacccgatg     1020

acccgtgcct ttatcaccca tgctggttcc catggtgttt atgaaagcat atgcaatggc     1080

gttcccatgg tgatgatgcc cttgtttggt gatcagatgg acaatgcaaa gcgcatggag     1140

actaagggag ctggagtgac cctgaatgtt ctggaaatga cttctgaaga tttagaaaat     1200

gctctaaaag cagtcatcaa tgacaaaagt tacaaggaga acatcatgcg cctctccagc     1260

cttcacaagg accgcccggt ggagccgctg gacctggccg tgttctgggt ggagtttgtg     1320

atgaggcaca agggcgcgcc acacctgcgc cccgcagccc acgacctcac ctggtaccag     1380

taccattcct tggac                                                      1395


<210>  5240
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  5240
ggaaaggtgt tggtggtgcc cactgatggc agcccctggc tcagcatgcg ggaggccttg       60

cgggagctcc atgccagagg ccaccaggcg gtggtcctca ccccagaggt gaatatgcac      120

atcaaagaag agaaattttt caccctgaca gcctatgctg ttccatggac ccagaaggaa      180

tttgatcgcg ttacgctggg ctacactcaa gggttctttg aaacagaaca tcttctgaag      240

agatattcta gaagtatggc aattatgaac aatgtatctt tggcccttca taggtgttgt      300

gtggagctac tgcataatga ggccctgatc aggcacctga atgctacttc ctttgatgtg      360

gttttaacag accccgttaa cctctgcggg gcggtgctgg ctaagtacct gtcgattcct      420

gctgtgtttt tttggaggta cattccatgt gacttagact ttaagggcac acagtgtcca      480

aatccttcct cctatattcc taagttacta acgaccaatt cagaccacat gacattcctg      540

caaagggtca agaacatgct ctaccctctg gccctgtcct acatttgcca tactttttct      600

gccccttatg caagtcttgc ctctgagctt tttcagagag aggtgtcagt ggtggatctt      660

gtcagctatg catccgtgtg gctgttccga ggggactttg tgatggacta ccccaggccg      720

atcatgccca acatggtctt cattgggggc atcaactgtg ccaacgggaa gccactatct      780

caggaatttg aagcctacat taatgcttct ggagaacatg gaattgtggt tttctctttg      840

ggatcaatgg tctcagaaat tccagagaag aaagctatgg caattgctga tgctttgggc      900

aaaatccctc agacagtcct gtggcggtac actggaaccc gaccatcgaa tcttgcgaac      960

aacacgatac ttgttaagtg gctaccccaa aacgatctgc ttggtcaccc gatgacccgt     1020

gcctttatca cccatgctgg ttcccatggt gtttatgaaa gcatatgcaa tggcgttccc     1080

atggtgatga tgcccttgtt tggtgatcag atggacaatg caaagcgcat ggagactaag     1140

ggagctggag tgaccctgaa tgttctggaa atgacttctg aagatttaga aaatgctcta     1200

aaagcagtca tcaatgacaa aagttacaag gagaacatca tgcgcctctc cagccttcac     1260

aaggaccgcc cggtggagcc gctggacctg gccgtgttct gggtggagtt tgtgatgagg     1320

cacaagggcg cgccacacct gcgccccgca gcccacgacc tcacctggta ccagtaccat     1380

tccttggac                                                             1389


<210>  5241
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  5241
gacgaagcca tccactgccc gccctgctcc gaggagaagc tggcgcgctg ccgccccccc       60

gtgggctgcg aggagctggt gcgagagccg ggctgcggct gttgcgccac ttgcgccctg      120

ggcttgggga tgccctgcgg ggtgtacacc ccccgttgcg gctcgggcct gcgctgctac      180

ccgccccgag gggtggagaa gcccctgcac acactgatgc acgggcaagg cgtgtgcatg      240

gagctggcgg agatcgaggc catccaggaa agcctgcagc cctctgacaa ggacgagggt      300

gaccacccca acaacagctt cagcccctgt agcgcccatg accgcaggtg cctgcagaag      360

cacttcgcca aaattcgaga ccggagcacc agtgggggca agatgaaggt caatggggcg      420

ccccgggagg atgcccggcc tgtgccccag ggctcctgcc agagcgagct gcaccgggcg      480

ctggagcggc tggccgcttc acagagccgc acccacgagg acctctacat catccccatc      540

cccaactgcg accgcaacgg caacttccac cccaagcagt gtcacccagc tctggatggg      600

cagcgtggca agtgctggtg tgtggaccgg aagacggggg tgaagcttcc ggggggcctg      660

gagccaaagg gggagctgga ctgccaccag ctggctgaca gctttcgaga g               711


<210>  5242
<211>  798
<212>  DNA
<213>  Homo Sapiens

<400>  5242
gcagagtcac actggtgcta cgaggttcaa gccgagtcct ccaactaccc ctgcttggtg       60

ccagtcaagt ggggtggaaa ctgccagaag gaccgccagt cccccatcaa catcgtcacc      120

accaaggcaa aggtggacaa aaaactggga cgcttcttct tctctggcta cgataagaag      180

caaacgtgga ctgtccaaaa taacgggcac tcagtgatga tgttgctgga gaacaaggcc      240

agcatttctg gaggaggact gcctgcccca taccaggcca aacagttgca cctgcactgg      300

tccgacttgc catataaggg ctcggagcac agcctcgatg gggagcactt tgccatggag      360

atgcacatag tacatgagaa agagaagggg acatcgagga atgtgaaaga ggcccaggac      420

cctgaagacg aaattgcggt gctggccttt ctggtggagg ctggaaccca ggtgaacgag      480

ggcttccagc cactggtgga ggcactgtct aatatcccca aacctgagat gagcactacg      540

atggcagaga gcagcctgtt ggacctgctc cccaaggagg agaaactgag gcactacttc      600

cgctacctgg gctcactcac cacaccgacc tgcgatgaga aggtcgtctg gactgtgttc      660

cgggagccca ttcagcttca cagagaacag atcctggcat tctctcagaa gctgtactac      720

gacaaggaac agacagtgag catgaaggac aatgtcaggc ccctgcagca gctggggcag      780

cgcacggtga taaagtcc                                                    798


<210>  5243
<211>  1101
<212>  DNA
<213>  Homo Sapiens

<400>  5243
ttaaccccag gaaaccccaa gtgggaacgc actaacttga cctacaggat tcgaaactat       60

accccacagc tgtcagaggc tgaggtagaa agagctatca aggatgcctt tgaactctgg      120

agtgttgcat cacctctcat cttcaccagg atctcacagg gagaggcaga tatcaacatt      180

gctttttacc aaagagatca cggtgacaat tctccatttg atggacccaa tggaatcctt      240

gctcatgcct ttcagccagg ccaaggtatt ggaggagatg ctcattttga tgccgaagaa      300

acatggacca acacctccgc aaattacaac ttgtttcttg ttgctgctca tgaatttggc      360

cattctttgg ggctcgctca ctcctctgac cctggtgcct tgatgtatcc caactatgct      420

ttcagggaaa ccagcaacta ctcactccct caagatgaca tcgatggcat tcaggccatc      480

tatggacttt caagcaaccc tatccaacct actggaccaa gcacacccaa accctgtgac      540

cccagtttga catttgatgc tatcaccaca ctccgtggag aaatactttt ctttaaagac      600

aggtacttct ggagaaggca tcctcagcta caaagagtcg aaatgaattt tatttctcta      660

ttctggccat cccttccaac tggtatacag gctgcttatg aagattttga cagagacctc      720

attttcctat ttaaaggcaa ccaatactgg gctctgagtg gctatgatat tctgcaaggt      780

tatcccaagg atatatcaaa ctatggcttc cccagcagcg tccaagcaat tgacgcagct      840

gttttctaca gaagtaaaac atacttcttt gtaaatgacc aattctggag atatgataac      900

caaagacaat tcatggagcc aggttatccc aaaagcatat caggtgcctt tccaggaata      960

gagagtaaag ttgatgcagt tttccagcaa gaacatttct tccatgtctt cagtggacca     1020

agatattacg catttgatct tattgctcag agagttacca gagttgcaag aggcaataaa     1080

tggcttaact gtagatatgg c                                               1101


<210>  5244
<211>  1647
<212>  DNA
<213>  Homo Sapiens

<400>  5244
gggcatccgt cctcgccacc tgtggtggac accgtgcatg gcaaagtgct ggggaagttc       60

gtcagcttag aaggatttgc acagcctgtg gccattttcc tgggaatccc ttttgccaag      120

ccgcctcttg gacccctgag gtttactcca ccgcagcctg cagaaccatg gagctttgtg      180

aagaatgcca cctcgtaccc tcctatgtgc acccaagatc ccaaggcggg gcagttactc      240

tcagagctat ttacaaaccg aaaggagaac attcctctca agctttctga agactgtctt      300

tacctcaata tttacactcc tgctgacttg accaagaaaa acaggctgcc ggtgatggtg      360

tggatccacg gaggggggct gatggtgggt gcggcatcaa cctatgatgg gctggccctt      420

gctgcccatg aaaacgtggt ggtggtgacc attcaatatc gcctgggcat ctggggattc      480

ttcagcacag gggatgaaca cagccggggg aactggggtc acctggacca ggtggctgcc      540

ctgcgctggg tccaggacaa cattgccagc tttggaggga acccaggctc tgtgaccatc      600

tttggagagt cagcgggagg agaaagtgtc tctgttcttg ttttgtctcc attggccaag      660

aatctcttcc accgggccat ttctgagagt ggcgtggccc tcacttctgt tctggtgaag      720

aaaggtgatg tcaagccctt ggctgagcaa attgctatca ctgctgggtg caaaaccacc      780

acctctgctg tcatggttca ctgcctgcga cagaagacgg aagaggagct cttggagacg      840

acattgaaaa tgaaattctt atctctggac ttacagggag accccagaga gagtcaaccc      900

cttctgggca ctgtgattga tgggatgctg ctgctgaaaa cacctgaaga gcttcaagct      960

gaaaggaatt tccacactgt cccctacatg gtcggaatta acaagcagga gtttggctgg     1020

ttgattccaa tgttgatgag ctatccactc tccgaagggc aactggacca gaagacagcc     1080

atgtcactcc tgtggaagtc ctatcccctt gtttgcattg ctaaggaact gattccagaa     1140

gccactgaga aatacttagg aggaacagac gacactgtca aaaagaaaga cctgttcctg     1200

gacttgatag cagatgtgat gtttggtgtc ccatctgtga ttgtggcccg gaaccacaga     1260

gatgctggag cacccaccta catgtatgag tttcagtacc gtccaagctt ctcatcagac     1320

atgaaaccca agacggtgat aggagaccac ggggatgagc tcttctccgt ctttggggcc     1380

ccatttttaa aagagggtgc ctcagaagag gagatcagac ttagcaagat ggtgatgaaa     1440

ttctgggcca actttgctcg caatggaaac cccaatgggg aagggctgcc ccactggcca     1500

gagtacaacc agaaggaagg gtatctgcag attggtgcca acacccaggc ggcccagaag     1560

ctgaaggaca aagaagtagc tttctggacc aacctctttg ccaagaaggc agtggagaag     1620

ccaccccaga cagaacacat agagctg                                         1647


<210>  5245
<211>  1995
<212>  DNA
<213>  Homo Sapiens

<400>  5245
aacttccaga actgtggccc tcgcccctgt gagacatctg tgtgtttgga tctccgggat       60

cattacctgg cctctgggaa cacaagtgtg gccccctgca ccgacttctt cagctttgcc      120

tgtggaaggg ccaaagagac caataattct tttcaggagc ttgccacaaa gaacaaaaac      180

cgacttcgga gaatactgga ggtccagaat tcctggcacc caggctctgg ggaggagaaa      240

gccttccagt tctacaactc ctgcatggat acacttgcca ttgaagctgc agggactggt      300

cccctcagac aagttattga ggagcttgga ggctggcgca tctctggtaa atggacttcc      360

ttaaacttta accgaacgct gagacttctg atgagtcagt atggccattt ccctttcttc      420

agagcctacc taggacctca tcctgcctct ccacacacac cagtcatcca gatagaccag      480

ccagagtttg atgttcccct caagcaagat caagaacaga agatctatgc ccagatcttt      540

cgggaatacc tgacttacct gaatcagctg ggaaccttgc tgggaggaga cccaagcaag      600

gtgcaagaac actcttcctt gtcaatctcc atcacttcac ggctgttcca gtttctgagg      660

cccctggagc agcggcgggc acagggcaag ctcttccaga tggtcactat cgaccagctc      720

aaggaaatgg cccccgccat cgactggttg tcctgcttgc aagcgacatt cacaccgatg      780

tccctgagcc cttctcagtc cctcgtggtc catgacgtgg aatatttgaa aaacatgtca      840

caactggtgg aggagatgct gctaaagcag agggactttc tgcagagcca catgatctta      900

gggctggtgg tgaccctttc tccagccctg gacagtcaat tccaggaggc acgcagaaag      960

ctcagccaga aactgcggga actgacagag caaccaccca tgcctgcccg cccacgatgg     1020

atgaagtgcg tggaggagac aggcacgttc ttcgagccca cgctggcggc tttgtttgtt     1080

cgtgaggcct ttggcccgag cacccgaagt gctgccatga aattattcac tgcgatccgg     1140

gatgccctca tcactcgcct cagaaacctt ccctggatga atgaggagac ccagaacatg     1200

gcccaggaca aggttgctca actgcaggtg gagatggggg cttcagaatg ggccctgaag     1260

ccagagctgg cccgacaaga atacaacgat atacagcttg gatcgagctt cctgcagtct     1320

gtcctgagct gtgtccggtc cctccgagct agaattgtcc agagcttctt gcagcctcac     1380

ccccaacaca ggtggaaggt gtccccttgg gacgtcaatg cttactattc ggtatctgac     1440

catgtggtag tctttccagc tggactcctc caacccccat tcttccaccc tggctatccc     1500

agagccgtga actttggcgc tgctggcagc atcatggccc acgagctgtt gcacatcttc     1560

taccagctct tactgcctgg gggctgcctc gcctgtgaca accatgccct ccaggaagct     1620

cacctgtgcc tgaagcgcca ttatgctgcc tttccattac ctagcagaac ctccttcaat     1680

gactccctca cattcttaga gaatgctgca gacgttgggg ggctagccat cgcgctgcag     1740

gcatacagca agaggctgtt acggcaccat ggggagactg tcctgcccag cctggacctc     1800

agcccccagc agatcttctt tcgaagctat gcccaggtga tgtgtaggaa gcccagcccc     1860

caggactctc acgacactca cagccctcca cacctccgag tccacgggcc cctcagcagc     1920

accccagcct ttgccaggta tttccgctgt gcacgtggtg ctctcttgaa cccctccagc     1980

cgctgccagc tctgg                                                      1995


<210>  5246
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5246
gatgagaaga agaaggggcc caaagtcacc gtcaaggtgt attttgacct acgaattgga       60

gatgaagatg taggccgggt gatctttggt ctcttcggaa agactgttcc aaaaacagtg      120

gataattttg tggccttagc tacaggagag aaaggatttg gctacaaaaa cagcaaattc      180

catcgtgtaa tcaaggactt catgatccag ggcggagact tcaccagggg agatggcaca      240

ggaggaaaga gcatctacgg tgagcgcttc cccgatgaga acttcaaact gaagcactac      300

gggcctggct gggtgagcat ggccaacgca ggcaaagaca ccaacggctc ccagttcttc      360

atcacgacag tcaagacagc ctggctagat ggcaagcatg tggtgtttgg caaagttcta      420

gagggcatgg aggtggtgcg gaaggtggag agcaccaaga cagacagccg ggataaaccc      480

ctgaaggatg tgatcatcgc agactgcggc aagatcgagg tggagaagcc ctttgccatc      540

gccaaggag                                                              549


<210>  5247
<211>  2013
<212>  DNA
<213>  Homo Sapiens

<400>  5247
cagctcagag gggatgggct aggcttcaga aaccggaaca acagcactgg agtcgccggg       60

ctctccgagg aggcatcagc agagcttcgc caccacctcc acagccctag agaccatcca      120

gatgagaaca aggatgtttc cacagagaat gggcatcatt tctggagcca cccagaccgt      180

gaaaaggagg atgaagatgt ctccaaggaa tatgggcacc tactcccagg ccacaggtcc      240

caagaccaca aagtcggaga tgagggtgtc tcaggtgagg aggtctttgc agagcatggt      300

gggcaggccc gtgggcacag aggccacggg agtgaagaca cggaagactc agctgagcac      360

aggcaccacc tccccagcca caggagccac agccatcaag acgaggatga ggatgaagtt      420

gtgtccagtg agcatcacca tcatatcctc aggcatggac accgaggcca tgatggggaa      480

gatgatgaag gagaagagga ggaggaggag gaggaggagg aagaggaggc ctccactgag      540

tatggacacc aggcccacag gcaccgaggc catgggagtg aagaggatga ggatgtctca      600

gatggacacc atcatcatgg ccccagccac aggcaccaag gccatgaaga agatgacgat      660

gatgatgatg atgatgatga tgatgatgat gatgatgatg tctccattga atatagacac      720

caggctcaca ggcaccaagg ccacgggatt gaagaggatg aagatgtctc agatggacac      780

catcatcgcg accccagcca caggcaccga agccatgaag aagatgacaa tgatgatgat      840

gatgtctcca ctgagtatgg acaccaggcc cacaggcacc aagaccacag aaaggaagag      900

gttgaggctg tctcaggtga acaccaccat catgtccctg accacaggca ccaaggccac      960

agagacgagg aagaagatga ggatgtgtcc actgaacgtt ggcaccaggg tccccaacat     1020

gtccaccatg gccttgtaga tgaggaagag gaagaagagg agatcacagt ccagttcggc     1080

cactatgttg caagccacca acctcgaggc cacaagagtg atgaagagga cttccaagat     1140

gagtataaaa cagaagtccc tcaccatcac caccacagag tccccaggga ggaagatgag     1200

gaggtctctg ctgagcttgg ccaccaggcc cccagccaca ggcaaagcca ccaagatgaa     1260

gaaactggcc atggtcaaag agggtccatc aaagagatga gccatcaccc cccaggacac     1320

acagtggtca aggatagaag ccatttgagg aaggatgatt ctgaggagga aaaggagaag     1380

gaagaggacc ccggctccca tgaggaagac gatgaaagtt cagagcaggg agagaaaggc     1440

acccatcatg gcagccggga ccaggaagat gaggaggatg aggaggaagg tcatggcctc     1500

agcctgaacc aggaggagga agaagaggaa gacaaggagg aggaggagga ggaagaagac     1560

gaggagagga gggaagagag ggctgaggtt ggggccccac tgagcccaga ccacagcgag     1620

gaggaagagg aggaggagga ggggctggag gaagatgagc cccgcttcac catcatcccc     1680

aacccactgg acaggagaga ggaggctgga ggtgcctcca gcgaggagga aagcggtgag     1740

gacacaggtc cacaggatgc tcaggagtat gggaactacc agccagggtc cctgtgtggc     1800

tactgctcct tctgcaatcg atgcactgaa tgtgagagct gtcactgtga tgaggagaac     1860

atgggtgagc actgcgacca gtgccagcac tgtcagttct gctatctctg cccgctggtc     1920

tgcgaaacgg tctgcgctcc aggaagctac gttgactatt tctcctcgtc cctttatcag     1980

gccctggcag acatgctgga aacgccggaa ccc                                  2013


<210>  5248
<211>  666
<212>  DNA
<213>  Homo Sapiens

<400>  5248
gctcgctccg cacccaagcc tatgtcaccc tcggatttcc tggataagct aatggggaga       60

acctccggat atgatgccag gatcaggccc aattttaaag gtcccccagt gaacgtgagc      120

tgcaacattt tcatcaacag ctttggttcc attgctgaga caaccatgga ctatagggtc      180

aacatcttcc tgcggcagca atggaacgac ccccgcctgg cctataatga ataccctgac      240

gactctctgg acctggaccc atccatgctg gactccatct ggaaacctga cctgttcttt      300

gccaacgaga agggggccca cttccatgag atcaccacag acaacaaatt gctaaggatc      360

tcccggaatg ggaatgtcct ctacagcatc agaatcaccc tgacactggc ctgccccatg      420

gacttgaaga atttccccat ggatgtccag acatgtatca tgcaactgga aagctttgga      480

tatacgatga atgacctcat ctttgagtgg caggaacagg gagccgtgca ggtagcagat      540

ggactaactc tgccccagtt tatcttgaag gaagagaagg acttgagata ctgcaccaag      600

cactacaaca caggtaaatt cacctgcatt gaggcccggt tccacctgga gcggcagatg      660

ggttac                                                                 666


<210>  5249
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  5249
aaagaccatg actccaggtc tggaaaacaa ccttcacaga ccctatctcc ttcagatttc       60

ttggacaagt taatgggaag gacatcagga tatgatgcaa gaatcaggcc aaattttaaa      120

ggtcctccag taaacgttac ttgcaatatt tttatcaaca gttttggatc agtcacagaa      180

acgaccatgg actaccgagt gaatattttt ctgagacaac agtggaatga ttcacggctg      240

gcgtacagtg agtacccaga tgactccctg gacttggacc catccatgct agactccatt      300

tggaaaccag atttgttctt tgccaatgag aagggtgcca acttccacga tgtcaccact      360

gacaacaaat tgctacggat ttcgaaaaat ggcaaagtgc tctacagtat cagactcacc      420

ttgaccttat cctgtcccat ggacttgaag aactttccga tggatgtcca gacctgtaca      480

atgcagctgg agagttttgg gtacacgatg aatgacctga tatttgagtg gttaagtgat      540

ggtccagtgc aagttgctga aggattgacc ctgccccagt ttattttgaa agaagagaag      600

gaacttggct actgtacaaa gcactacaac actggaaagt ttacctgcat tgaggtcaag      660

tttcatctgg aacgccaaat gggatat                                          687


<210>  5250
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  5250
cagaatgaga cggagcccat cgtgctggag ggcaagtgcc tggtggtgtg cgactccaac       60

cccacgtccg accccacggg cactgccctg ggcatctctg tgcgctctgg cagcgccaag      120

gtggctttct ctgccatcag gagcaccaac cacgagccgt ccgagatgag taatcgcacc      180

atgatcatct acttcgacca ggtactagtg aacattggga acaactttga ttcagaacgc      240

agcactttca tcgccccgcg caaagggatc tacagtttta acttccacgt ggtaaaagtc      300

tacaacagac aaaccataca ggtgagcctc atgctaaacg ggtggccggt gatttcagcc      360

ttcgctggtg accaggacgt gacccgggag gccgccagca acggagtcct aatccaaatg      420

gagaaaggcg accgagcata cctcaagctg gagcggggaa acttgatggg gggctggaag      480

tactcgacct tctccggatt cctggtgttt cctctc                                516


<210>  5251
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5251
gacctgcgcg tggacaccaa gtcgcgggca gcgtgggctc gccttctgca agagcacccc       60

aacgcgcgca aatacaaagg agccaacaag aagggcttgt ccaagggctg cttcggcctc      120

aagctggacc gaatcggctc catgagcggc ctgggatgt                             159


<210>  5252
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  5252
atcatcgggg gcacagaatg caagccacat tcccgcccct acatggccta cctggaaatt       60

gtaacttcca acggtccctc aaaattttgt ggtggtttcc ttataagacg gaactttgtg      120

ctgacggctg ctcattgtgc aggaaggtct ataacagtca cccttggagc ccataacata      180

acagaggaag aagacacatg gcagaagctt gaggttataa agcaattccg tcatccaaaa      240

tataacactt ctactcttca ccacgatatc atgttactaa agttgaagga gaaagccagc      300

ctgaccctgg ctgtggggac actccccttc ccatcacaat tcaactttgt cccacctggg      360

agaatgtgcc gggtggctgg ctggggaaga acaggtgtgt tgaagccggg ctcagacact      420

ctgcaagagg tgaagctgag actcatggat ccccaggcct gcagccactt cagagacttt      480

gaccacaatc ttcagctgtg tgtgggcaat cccaggaaga caaaatctgc atttaaggga      540

gactctgggg gccctcttct gtgtgctggg gtggcccagg gcatcgtatc ctatggacgg      600

tcggatgcaa agccccctgc tgtcttcacc cgaatctccc attaccggcc ctggatcaac      660

cagatcctgc aggcaaat                                                    678


<210>  5253
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  5253
ttcaccctca acctgccctg gaccgactgt ggccacacct ggaacagccc caactgtacc       60

gaccccaagc tcctcaatgg ctccgtgctt ggcaaccaca ccaagtactc caagtacaag      120

ttcacgccgg cagccgagtt ttatgagcgt ggtgtcctgc accttcacga gagcagcggg      180

attcatgaca tcggcctgcc c                                                201


<210>  5254
<211>  783
<212>  DNA
<213>  Homo Sapiens

<400>  5254
actgaaagca gaatgcactg gcccggaaga gaagtccacg agatgtctaa gaaaggcagt       60

aggccccaaa gacaaagacg agaagtacat gaagatgccc acaagcaagt cagcccaatt      120

ctgagacgaa gtcctgacat caccaaatcg cctctgacaa agtcagaaca gcttctgagg      180

atagatgacc atgatttcag catgaggcct ggctttggag gccctgccat tcctgttggt      240

gtggatgtgc aggtggagag tttggatagc atctcagagg ttgacatgga ctttacgatg      300

accctctacc tgaggcacta ctggaaggac gagaggctgt cttttccaag caccaacaac      360

ctcagcatga cgtttgatgg ccggctggtc aagaagatct gggtccctga catgtttttc      420

gtgcactcca aacgctcctt catccacgac accaccacag acaacgtcat gttgcgggtc      480

cagcctgatg ggaaagtgct ctatagtctc agggttacag taactgcaat gtgcaacatg      540

gacttcagcc gatttccctt ggacacacaa acgtgctctc ttgaaattga aagctatgcc      600

tatacagaag atgacctcat gctgtactgg aaaaagggca atgactcctt aaagacagat      660

gaacggatct cactctccca gttcctcatt caggaattcc acaccaccac caaactggct      720

ttctacagca gcacaggctg gtacaaccgt ctctacatta atttcacgtt gcgtcgccac      780

atc                                                                    783


<210>  5255
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  5255
atcgtgggcg ggcacgaggc gcagccacac tcccggccct acatggcctc cctgcagatg       60

cgggggaacc cgggcagcca cttctgcgga ggcaccttga tccaccccag cttcgtgctg      120

acggccgcgc actgcctgcg ggacataccc cagcgcctgg tgaacgtggt gctcggagcc      180

cacaacgtgc ggacgcagga gcccacccag cagcacttct cggtggctca ggtgtttctg      240

aacaactacg acgcggagaa caaactgaac gacgttctcc tcatccagct gagcagccca      300

gccaacctca gtgcctccgt cgccacagtc cagctgccac agcaggacca gccagtgccc      360

cacggcaccc agtgcctggc catgggctgg ggccgcgtgg gtgcccacga ccccccagcc      420

caggtcctgc aggagctcaa tgtcaccgtg gtcaccttct tctgccggcc acataacatt      480

tgcactttcg tccctcgccg caaggccggc atctgcttcg gagactcagg tggccccctg      540

atctgtgatg gcatcatcca aggaatagac tccttcgtga tctggggatg tgccacccgc      600

cttttccctg acttcttcac gcgggtagcc ctctacgtgg actggatccg ttccacgctg      660

cgc                                                                    663


<210>  5256
<211>  894
<212>  DNA
<213>  Homo Sapiens

<400>  5256
tacctagagc tgagggaagc ggcggactac gatcctttcc tgctcttcag cgccaacctg       60

aagcgggagc tggctgggga gcagccgtac cgccgcgctc tgcggtgcct ggacatgctg      120

agcctccagg gccagttcac cttcaccgcc gaccggccgc agctgcactg cgcagccttc      180

ttcatcagcg agcccgagga gttcattacc atccactacg accaggtctc catcgactgt      240

cagggcggcg acttcctgaa ggtatttgat ggttggattc tcaaggggga gaagttcccc      300

agttcccagg atcatcctct cccctcagct gagcggtaca tagatttctg tgagagtggt      360

cttagcagga ggagcatcag atcttcccag aatgtggcca tgatcttctt ccgagtccat      420

gaaccaggaa atggattcac attaaccata aagacagacc ccaacctctt tccttgcaat      480

gtcatttctc agactccaaa tggaaagttt accctggtag ttccacacca gcatcgaaac      540

tgcagcttct ccataattta tcctgtggtg atcaaaatat ctgatcttac cctgggacac      600

gtaaatggtc ttcagttaaa gaaatcctca gcaggttgcg agggaatagg agactttgtg      660

gagctgctgg gaggaactgg attggaccct tccaagatga cgcctttagc tgatctctgc      720

tacccctttc atggcccggc ccagatgaaa gttggctgtg acaacactgt ggtgcgcatg      780

gtctccagtg gaaaacacgt aaatcgtgtg acttttgagt atcgtcagct ggagccgtac      840

gagctggaaa acccaaatgg aaacagtatc ggggaattct gtttgtctgg tctt            894


<210>  5257
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  5257
cggtgcccag gctgcgggca aggggtgcag gcgggttgtc cagggggctg cgtggaggag       60

gaggatgggg ggtcgccagc cgagggctgc gcggaagctg agggctgtct caggagggag      120

gggcaggagt gcggggtcta cacccctaac tgcgccccag gactgcagtg ccatccgccc      180

aaggacgacg aggcgccttt gcgggcgctg ctgctcggcc gaggccgctg ccttccggcc      240

cgcgcgcctg ctgttgcaga ggagaatcct aaggagagta aaccccaagc aggcactgcc      300

cgcccacagg atgtgaaccg cagagaccaa cagaggaatc caggcacctc taccacgccc      360

tcccagccca attctgcggg tgtccaagac actgagatgg gcccatgccg tagacatctg      420

gactcagtgc tgcagcaact ccagactgag gtctaccgag gggctcaaac actctacgtg      480

cccaattgtg accatcgagg cttctaccgg aagcggcagt gccgctcctc ccaggggcag      540

cgccgaggtc cctgctggtg tgtggatcgg atgggcaagt ccctgccagg gtctccagat      600

ggcaatggaa gctcctcctg ccccactggg agtagcggc                             639


<210>  5258
<211>  756
<212>  DNA
<213>  Homo Sapiens

<400>  5258
ctgggctcct tcgtgcactg cgagccctgc gacgagaaag ccctctccat gtgccccccc       60

agccccctgg gctgcgagct ggtcaaggag ccgggctgcg gctgctgcat gacctgcgcc      120

ctggccgagg ggcagtcgtg cggcgtctac accgagcgct gcgcccaggg gctgcgctgc      180

ctcccccggc aggacgagga gaagccgctg cacgccctgc tgcacggccg cggggtttgc      240

ctcaacgaaa agagctaccg cgagcaagtc aagatcgaga gagactcccg tgagcacgag      300

gagcccacca cctctgagat ggccgaggag acctactccc ccaagatctt ccggcccaaa      360

cacacccgca tctccgagct gaaggctgaa gcagtgaaga aggaccgcag aaagaagctg      420

acccagtcca agtttgtcgg gggagccgag aacactgccc acccccggat catctctgca      480

cctgagatga gacaggagtc tgagcagggc ccctgccgca gacacatgga ggcttccctg      540

caggagctca aagccagccc acgcatggtg ccccgtgctg tgtacctgcc caattgtgac      600

cgcaaaggat tctacaagag aaagcagtgc aaaccttccc gtggccgcaa gcgtggcatc      660

tgctggtgcg tggacaagta cgggatgaag ctgccaggca tggagtacgt tgacggggac      720

tttcagtgcc acaccttcga cagcagcaac gttgag                                756


<210>  5259
<211>  780
<212>  DNA
<213>  Homo Sapiens

<400>  5259
ctgaagatcg cagccttcaa catccagaca tttggggaga ccaagatgtc caatgccacc       60

ctcgtcagct acattgtgca gatcctgagc cgctatgaca tcgccctggt ccaggaggtc      120

agagacagcc acctgactgc cgtggggaag ctgctggaca acctcaatca ggatgcacca      180

gacacctatc actacgtggt cagtgagcca ctgggacgga acagctataa ggagcgctac      240

ctgttcgtgt acaggcctga ccaggtgtct gcggtggaca gctactacta cgatgatggc      300

tgcgagccct gcgggaacga caccttcaac cgagagccag ccattgtcag gttcttctcc      360

cggttcacag aggtcaggga gtttgccatt gttcccctgc atgcggcccc gggggacgca      420

gtagccgaga tcgacgctct ctatgacgtc tacctggatg tccaagagaa atggggcttg      480

gaggacgtca tgttgatggg cgacttcaat gcgggctgca gctatgtgag accctcccag      540

tggtcatcca tccgcctgtg gacaagcccc accttccagt ggctgatccc cgacagcgct      600

gacaccacag ctacacccac gcactgtgcc tatgacagga tcgtggttgc agggatgctg      660

ctccgaggcg ccgttgttcc cgactcggct cttcccttta acttccaggc tgcctatggc      720

ctgagtgacc aactggccca agccatcagt gaccactatc cagtggaggt gatgctgaag      780


<210>  5260
<211>  1221
<212>  DNA
<213>  Homo Sapiens

<400>  5260
tcccaggtga gtcagaactg ccacaatggc agctatgaaa tcagcgtcct gatgatgggc       60

aactcagcct ttgcagagcc cctgaaaaac ttggaagatg cggtgaatga ggggctggaa      120

atagtgagag gacgtctgca aaatgctggc ctaaatgtga ctgtgaacgc tactttcatg      180

tattcggatg gtctgattca taactcaggc gactgccgga gtagcacctg tgaaggcctc      240

gacctactca ggaaaatttc aaatgcacaa cggatgggct gtgtcctcat agggccctca      300

tgtacatact ccaccttcca gatgtacctt gacacagaat tgagctaccc catgatctca      360

gctggaagtt ttggattgtc atgtgactat aaagaaacct taaccaggct gatgtctcca      420

gctagaaagt tgatgtactt cttggttaac ttttggaaaa ccaacgatct gcccttcaaa      480

acttattcct ggagcacttc gtatgtttac aagaatggta cagaaactga ggactgtttc      540

tggtacctta atgctctgga ggctagcgtt tcctatttct cccacgaact cggctttaag      600

gtggtgttaa gacaagataa ggagtttcag gatatcttaa tggaccacaa caggaaaagc      660

aatgtgatta ttatgtgtgg tggtccagag ttcctctaca agctgaaggg tgaccgagca      720

gtggctgaag acattgtcat tattctagtg gatcttttca atgaccagta cttggaggac      780

aatgtcacag cccctgacta tatgaaaaat gtccttgttc tgacgctgtc tcctgggaat      840

tcccttctaa atagctcttt ctccaggaat ctatcaccaa caaaacgaga ctttgctctt      900

gcctatttga atggaatcct gctctttgga catatgctga agatatttct tgaaaatgga      960

gaaaatatta ccacccccaa atttgctcat gctttcagga atctcacttt tgaagggtat     1020

gacggtccag tgaccttgga tgactggggg gatgttgaca gtaccatggt gcttctgtat     1080

acctctgtgg acaccaagaa atacaaggtt cttttgacct atgataccca cgtaaataag     1140

acctatcctg tggatatgag ccccacattc acttggaaga actctaaact tcctaatgat     1200

attacaggcc ggggccctca g                                               1221


<210>  5261
<211>  732
<212>  DNA
<213>  Homo Sapiens

<400>  5261
cagcctaatg agctttctgg ctccatagat catcaaactt cagttcagca acttccaggt       60

gagttctttt cacttgaaaa cccttctgat gctgaggctt tatatgagac ttcttcaggc      120

ctgaacactt taagtgagca tggttccagt gagcatggtt caagcaagca cactgtggcc      180

gagcacactt ctggagaaca tgctgagagt gagcatgctt caggtgagcc cgctgcgact      240

gaacatgctg aaggtgagca tactgtaggt gagcagcctt caggagaaca gccttcaggt      300

gaacacctct ccggagaaca gcctttgagt gagcttgagt caggtgaaca gccttcagat      360

gaacagcctt caggtgaaca tggctccggt gaacagcctt ctggtgagca ggcctcgggt      420

gaacagcctt caggtgagca cgcttcaggg gaacaggctt caggtgcacc aatttcaagc      480

acatctacag gcacaatatt aaattgctac acatgtgctt atatgaatga tcaaggaaaa      540

tgtcttcgtg gagagggaac ctgcatcact cagaattccc agcagtgcat gttaaagaag      600

atctttgaag gtggaaaact ccaattcatg gttcaagggt gtgagaacat gtgcccatct      660

atgaacctct tctcccatgg aacgaggatg caaattatat gctgtcgaaa tcaatctttc      720

tgcaataaga tc                                                          732


<210>  5262
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  5262
gccacggggg ccgagggcaa aaggaagctg cagatcgggg tcaagaagcg ggtggaccac       60

tgtcccatca aatcgcgcaa aggggatgtc ctgcacatgc actacacggg gaagctggaa      120

gatgggacag agtttgacag cagcctgccc cagaaccagc cctttgtctt ctcccttggc      180

acaggccagg tcatcaaggg ctgggaccag gggctgctgg ggatgtgtga gggggaaaag      240

cgcaagctgg tgatcccatc cgagctaggg tatggagagc ggggagctcc cccaaagatt      300

ccaggcggtg caaccctggt gttcgaggtg gagctgctca aaatagagcg acgaactgag      360

ctg                                                                    363


<210>  5263
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  5263
gctatacttg gtagatcaga aactcaggag tgtcttttct ttaatgctaa ttgggaaaaa       60

gacagaacca atcaaactgg tgttgaaccg tgttatggtg acaaagataa acggcggcat      120

tgttttgcta cctggaagaa tatttctggt tccattgaaa tagtgaaaca aggttgttgg      180

ctggatgata tcaactgcta tgacaggact gattgtgtag aaaaaaaaga cagccctgaa      240

gtatattttt gttgctgtga gggcaatatg tgtaatgaaa agttttctta ttttccagag      300

atggaagtca cacagcccac ttcaaatcca gttacaccta agccaccc                   348


<210>  5264
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  5264
gcgaagctga ttgcgctcac cctcttgggg atgggactgg cactcttcag gaaccaccag       60

tcttcttacc aaacacgact taatgctctc cgagaggtac aacccgtaga acttcctaac      120

tgtaatttag ttaaaggaat cgaaactggc tctgaagact tggagatact gcctaatgga      180

ctggctttca ttagctctgg attaaagtat cctggaataa agagcttcaa ccccaacagt      240

cctggaaaaa tacttctgat ggacctgaat gaagaagatc caacagtgtt ggaattgggg      300

atcactggaa gtaaatttga tgtatcttca tttaaccctc atgggattag cacattcaca      360

gatgaagata atgccatgta cctcctggtg gtgaaccatc cagatgccaa gtccacagtg      420

gagttgttta aatttcaaga agaagaaaaa tcgcttttgc atctaaaaac catcagacat      480

aaacttctgc ctaatttgaa tgatattgtt gctgtgggac ctgagcactt ttatggcaca      540

aatgatcact attttcttga cccctactta caatcctggg agatgtattt gggtttagcg      600

tggtcgtatg ttgtctacta tagtccaagt gaagttcgag tggtggcaga aggatttgat      660

tttgctaatg gaatcaacat ttcacccgat ggcaagtatg tctatatagc tgagttgctg      720

gctcataaga ttcatgtgta tgaaaagcat gctaattgga ctttaactcc attgaagtcc      780

cttgacttta ataccctcgt ggataacata tctgtggatc ctgagacagg agacctttgg      840

gttggatgcc atcccaatgg catgaaaatc ttcttctatg actcagagaa tcctcctgca      900

tcagaggtgc ttcgaatcca gaacattcta acagaagaac ctaaagtgac acaggtttat      960

gcagaaaatg gcacagtgtt gcaaggcagt acagttgcct ctgtgtacaa agggaaactg     1020

ctgattggca cagtgtttca caaagctctt tactgtgagc tc                        1062


<210>  5265
<211>  1197
<212>  DNA
<213>  Homo Sapiens

<400>  5265
agtacccaga cccagagttc atgctccgtt ccctcagcac aggagccctt ggtcaatgga       60

atacaagtac tcatggagaa ctcggtgact tcatcagcct acccaaaccc cagcatcctg      120

attgccatga atctggccgg agcctacaac ttgaaggccc agaagctcct gacttaccag      180

ctcatgtcca gcgacaacaa cgatctaacc attgggcagc tcggcctcac catcatggcc      240

ctcacctcct cctgccgaga ccctggggat aaagtatcca ttctacaaag acaaatggag      300

aactgggcac cttccagccc caacgctgaa gcatcagcct tctatgggcc cagtctagcg      360

atcttggcac tgtgccagaa gaactctgag gcgaccttgc cgatagccgt ccgctttgcc      420

aagaccctgc tggccaactc ctctcccttc aatgtagaca caggagcaat ggcaaccttg      480

gctctgacct gtatgtacaa caagatccct gtaggttcag aggaaggtta cagatccctg      540

tttggtcagg tactaaagga tattgtggag aaaatcagca tgaagatcaa agataatggc      600

atcattggag acatctacag tactggcctc gccatgcagg ctctctctgt aacacctgag      660

ccatctaaaa aggaatggaa ctgcaagaag actacggata tgatactcaa tgagattaag      720

caggggaaat tccacaaccc catgtccatt gctcaaatcc tcccttccct gaaaggcaag      780

acatacctag atgtgcccca ggtcacttgt agtcctgatc atgaggtaca accaactcta      840

cccagcaacc ctggccctgg ccccacctct gcatctaaca tcactgtcat atacaccata      900

aataaccagc tgaggggggt tgagctgctc ttcaacgaga ccatcaatgt tagtgtgaaa      960

agtgggtcag tgttacttgt tgtcctagag gaagcacagc gcaaaaatcc tatgttcaaa     1020

tttgaaacca caatgacatc ttggggcctt gtcgtctctt ctatcaacaa tatcgcggaa     1080

aatgttaatc acaagacata ctggcagttt cttagtggtg taacaccttt gaatgaaggg     1140

gttgctgact acataccctt caaccacgag cacatcacag ccaatttcac acagtac        1197


<210>  5266
<211>  519
<212>  DNA
<213>  Homo Sapiens

<400>  5266
gctgtgatgc cccctacacc accaccccag ggagagtatc tgccagatat ggggctggga       60

attgatggcg tgaaaccccc ccatgcctac ggggctaaga aaggcaagaa tggagggcca      120

gcctatgaga tgcctgcatt taccgccgag ctaaccgcac ctttcccacc ggtgggggcc      180

ccagtgaagt ttaacaaact gctgtataac ggcagacaga actacaaccc gcagacaggc      240

atcttcacct gtgaggtccc tggtgtctac tactttgcat accacgttca ctgcaagggg      300

ggcaacgtgt gggttgctct attcaagaac aacgagcccg tgatgtacac gtacgacgag      360

tacaaaaagg gcttcctgga ccaggcatct gggagtgcag tgctgctgct caggcccgga      420

gaccgggtgt tcctccagat gccctcagaa caggctgcag gactgtatgc cgggcagtat      480

gtccactcct ccttttcagg atatttattg tatcccatg                             519


<210>  5267
<211>  1200
<212>  DNA
<213>  Homo Sapiens

<400>  5267
gagcctgccg tctacttcaa ggagcagttt ctggacggag acgggtggac ttcccgctgg       60

atcgaatcca aacacaagtc agattttggc aaattcgttc tcagttccgg caagttctac      120

ggtgacgagg agaaagataa aggtttgcag acaagccagg atgcacgctt ttatgctctg      180

tcggccagtt tcgagccttt cagcaacaaa ggccagacgc tggtggtgca gttcacggtg      240

aaacatgagc agaacatcga ctgtgggggc ggctatgtga agctgtttcc taatagtttg      300

gaccagacag acatgcacgg agactcagaa tacaacatca tgtttggtcc cgacatctgt      360

ggccctggca ccaagaaggt tcatgtcatc ttcaactaca agggcaagaa cgtgctgatc      420

aacaaggaca tccgttgcaa ggatgatgag tttacacacc tgtacacact gattgtgcgg      480

ccagacaaca cctatgaggt gaagattgac aacagccagg tggagtccgg ctccttggaa      540

gacgattggg acttcctgcc acccaagaag ataaaggatc ctgatgcttc aaaaccggaa      600

gactgggatg agcgggccaa gatcgatgat cccacagact ccaagcctga ggactgggac      660

aagcccgagc atatccctga ccctgatgct aagaagcccg aggactggga tgaagagatg      720

gacggagagt gggaaccccc agtgattcag aaccctgagt acaagggtga gtggaagccc      780

cggcagatcg acaacccaga ttacaagggc acttggatcc acccagaaat tgacaacccc      840

gagtattctc ccgatcccag tatctatgcc tatgataact ttggcgtgct gggcctggac      900

ctctggcagg tcaagtctgg caccatcttt gacaacttcc tcatcaccaa cgatgaggca      960

tacgctgagg agtttggcaa cgagacgtgg ggcgtaacaa aggcagcaga gaaacaaatg     1020

aaggacaaac aggacgagga gcagaggctt aaggaggagg aagaagacaa gaaacgcaaa     1080

gaggaggagg aggcagagga caaggaggat gatgaggaca aagatgagga tgaggaggat     1140

gaggaggaca aggaggaaga tgaggaggaa gatgtccccg gccaggccaa ggacgagctg     1200


<210>  5268
<211>  1326
<212>  DNA
<213>  Homo Sapiens

<400>  5268
gaccccgtgc tctgcttcac ccagtatgaa gaatcctccg gcaagtgcaa gggcctcctg       60

gggggtggtg tcagcgtgga agactgctgt ctcaacactg cctttgccta ccagaaacgt      120

agtggtgggc tctgtcagcc ttgcaggtcc ccacgatggt ccctttggtc cacatgggcc      180

ccctgttcgg tgacgtgctc tgagggctcc cagctgcggt accggcgctg tgtgggctgg      240

aatgggcagt gctctggaaa ggtggcacct gggaccctgg agtggcagct ccaggcctgt      300

gaggaccagc agtgctgtcc tgagatgggc ggctggtctg gctgggggcc ctgggagcct      360

tgctctgtca cctgctccaa agggacccgg acccgcaggc gagcctgtaa tcaccctgct      420

cccaagtgtg ggggccactg cccaggacag gcacaggaat cagaggcctg tgacacccag      480

caggtctgcc ccacacacgg ggcctgggcc acctggggcc cctggacccc ctgctcagcc      540

tcctgccacg gtggacccca cgaacctaag gagacacgaa gccgcaagtg ttctgcacct      600

gagccctccc agaaacctcc tgggaagccc tgcccggggc tagcctacga gcagcggagg      660

tgcaccggcc tgccaccctg cccagtggct gggggctggg ggccttgggg ccctgtgagc      720

ccctgccctg tgacctgtgg cctgggccag accatggaac aacggacgtg caatcaccct      780

gtgccccagc atgggggccc cttctgtgct ggcgatgcca cccggaccca catctgcaac      840

acagctgtgc cctgccctgt ggatggggag tgggactcgt ggggggagtg gagcccctgt      900

atccgacgga acatgaagtc catcagctgt caagaaatcc cgggccagca gtcacgcggg      960

aggacctgca ggggccgcaa gtttgacgga catcgatgtg ccgggcaaca gcaggatatc     1020

cggcactgct acagcatcca gcactgcccc ttgaaaggat catggtcaga gtggagtacc     1080

tgggggctgt gcatgccccc ctgtggacct aatcctaccc gtgcccgcca gcgcctctgc     1140

acacccttgc tccccaagta cccgcccacc gtttccatgg tcgaaggtca gggcgagaag     1200

aacgtgacct tctgggggag accgctgcca cggtgtgagg agctacaagg gcagaagctg     1260

gtggtggagg agaaacgacc atgtctacac gtgcctgctt gcaaagaccc tgaggaagag     1320

gaactc                                                                1326


<210>  5269
<211>  366
<212>  DNA
<213>  Homo Sapiens

<400>  5269
gggagtgcct cggcccaatc taggaccttg gcaggtggca tccatgccac agacctcaat       60

gacaagagtg tgcagtgtgc cctggacttt gccatcagcg agtacaacaa ggtcattaat      120

aaggatgagt actacagccg ccctctgcag gtgatggctg cctaccagca gatcgtgggt      180

ggggtgaact actacttcaa tgtgaagttc ggtcgaacca catgcaccaa gtcccagccc      240

aacttggaca actgtccctt caatgaccag ccaaaactga aagaggaaga gttctgctct      300

ttccagatca atgaagttcc ctgggaggat aaaatttcca ttctgaacta caagtgccgg      360

aaagtc                                                                 366


<210>  5270
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  5270
cagagtgtga acgatcccgg gaacatgtcc tttgtgaagg agacggtgga caagctgttg       60

aaaggctacg acattcgcct aagacccgac ttcgggggtc ccccggtctg cgtggggatg      120

aacatcgaca tcgccagcat cgacatggtt tccgaagtca acatggatta taccttaacc      180

atgtattttc aacaatattg gagagataaa aggctcgcct attctgggat ccctctcaac      240

ctcacgcttg acaatcgagt ggctgaccag ctatgggtgc ccgacacata tttcttaaat      300

gacaaaaagt catttgtgca tggagtgaca gtgaaaaacc gcatgatccg tcttcaccct      360

gatgggacag tgctgtatgg gctcagaatc accacgacag cagcatgcat gatggacctc      420

aggagatacc ccctggacga gctgaactgc actctggaaa ttgaaagcta tggctacacc      480

acggatgaca ttgagtttta ctggcgaggc ggggacaagg ctgttaccgg agtggaaagg      540

attgagctcc cgcagttctc catcgtggag caccgtctgg tctcgaggaa tgttgtcttc      600

gccacaggtg cctatcctcg actgtcactg agctttcggt tgaagaggaa cattggatac      660


<210>  5271
<211>  720
<212>  DNA
<213>  Homo Sapiens

<400>  5271
agaaaaccca agaggaagcg atggacaggg caggtggaaa tgcccaagcc aagtcactta       60

tataagaaga accttgatgt gaccaagatc cggaagggaa agcctcagca gcttctcaga      120

gtggacgagc acgacttcag catgagaccc gccttcggag gccctgccat cccggtgggc      180

gtggacgtac aggtggagag cctggacagc atctccgagg tggacatgga cttcactatg      240

accctgtacc tgcggcatta ctggaaggat gagaggctag ctttctccag cgccagcaac      300

aagagcatga ccttcgatgg ccggctggtg aagaagatct gggtccctga tgtcttcttt      360

gttcactcca aaagatcgtt cactcatgac accaccactg acaacatcat gctgagggtg      420

ttcccagatg gacacgtgct gtacagcatg aggattacgg tcactgccat gtgcaacatg      480

gacttcagcc actttcccct ggactcccag acctgttctt tggagctgga gagctatgcc      540

tatacagatg aagatctaat gctgtactgg aagaatgggg atgaatccct aaaaacagat      600

gagaagatct ccttgtctca gtttctgatt cagaaatttc acacaacttc caggctggcc      660

ttctacagca gcactggctg gtacaaccgt ctgtacatta acttcacgtt gcgtcgccac      720


<210>  5272
<211>  1728
<212>  DNA
<213>  Homo Sapiens

<400>  5272
acgcggtgcc cagatggtca gttctgccct gtggcctgct gcctggaccc cggaggagcc       60

agctacagct gctgccgtcc ccttctggac aaatggccca caacactgag caggcatctg      120

ggtggcccct gccaggttga tgcccactgc tctgccggcc actcctgcat ctttaccgtc      180

tcagggactt ccagttgctg ccccttccca gaggccgtgg catgcgggga tggccatcac      240

tgctgcccac ggggcttcca ctgcagtgca gacgggcgat cctgcttcca aagatcaggt      300

aacaactccg tgggtgccat ccagtgccct gatagtcagt tcgaatgccc ggacttctcc      360

acgtgctgtg ttatggtcga tggctcctgg gggtgctgcc ccatgcccca ggcttcctgc      420

tgtgaagaca gggtgcactg ctgtccgcac ggtgccttct gcgacctggt tcacacccgc      480

tgcatcacac ccacgggcac ccaccccctg gcaaagaagc tccctgccca gaggactaac      540

agggcagtgg ccttgtccag ctcggtcatg tgtccggacg cacggtcccg gtgccctgat      600

ggttctacct gctgtgagct gcccagtggg aagtatggct gctgcccaat gcccaacgcc      660

acctgctgct ccgatcacct gcactgctgc ccccaagaca ctgtgtgtga cctgatccag      720

agtaagtgcc tctccaagga gaacgctacc acggacctcc tcactaagct gcctgcgcac      780

acagtggggg atgtgaaatg tgacatggag gtgagctgcc cagatggcta tacctgctgc      840

cgtctacagt cgggggcctg gggctgctgc ccttttaccc aggctgtgtg ctgtgaggac      900

cacatacact gctgtcccgc ggggtttacg tgtgacacgc agaagggtac ctgtgaacag      960

gggccccacc aggtgccctg gatggagaag gccccagctc acctcagcct gccagaccca     1020

caagccttga agagagatgt cccctgtgat aatgtcagca gctgtccctc ctccgatacc     1080

tgctgccaac tcacgtctgg ggagtggggc tgctgtccaa tcccagaggc tgtctgctgc     1140

tcggaccacc agcactgctg cccccagggc tacacgtgtg tagctgaggg gcagtgtcag     1200

cgaggaagcg agatcgtggc tggactggag aagatgcctg cccgccgggc ttccttatcc     1260

caccccagag acatcggctg tgaccagcac accagctgcc cggtggggca gacctgctgc     1320

ccgagcctgg gtgggagctg ggcctgctgc cagttgcccc atgctgtgtg ctgcgaggat     1380

cgccagcact gctgcccggc tggctacacc tgcaacgtga aggctcgatc ctgcgagaag     1440

gaagtggtct ctgcccagcc tgccaccttc ctggcccgta gccctcacgt gggtgtgaag     1500

gacgtggagt gtggggaagg acacttctgc catgataacc agacctgctg ccgagacaac     1560

cgacagggct gggcctgctg tccctaccgc cagggcgtct gttgtgctga tcggcgccac     1620

tgctgtcctg ctggcttccg ctgcgcagcc aggggtacca agtgtttgcg cagggaggcc     1680

ccgcgctggg acgccccttt gagggaccca gccttgagac agctgctg                  1728


<210>  5273
<211>  1929
<212>  DNA
<213>  Homo Sapiens

<400>  5273
tcagctctaa gggactcagc actaaatctc ttcaatgatc ccatgtggaa tcagcaatgg       60

tacttgcaag ataccaggat gacggcagcc ctgcccaagc tggaccttca tgtgatacct      120

gtttggcaaa aaggcattac gggcaaagga gttgttatca ccgtactgga tgatggtttg      180

gagtggaatc acacggacat ttatgccaac tatgatccag aggctagcta tgattttaat      240

gataatgacc atgatccatt tccccgatat gatcccacaa acgagaacaa acacgggacc      300

agatgtgcag gagaaattgc catgcaagca aataatcaca aatgcggggt tggagttgca      360

tacaattcca aagttggagg cataagaatg ctggatggca ttgtgacgga tgctattgag      420

gccagttcaa ttggattcaa tcctggacac gtggatattt acagtgcaag ctggggccct      480

aatgatgatg ggaaaactgt ggaggggcct ggccggctag cccagaaggc ttttgaatat      540

ggtgtcaaac aggggagaca ggggaagggg tccatcttcg tctgggcttc gggaaacggg      600

gggcgtcagg gagataattg tgactgtgat ggctacacag acagcatcta caccatctcc      660

atcagcagtg cctcccagca aggcctatcc ccctggtacg ctgagaagtg ctcctccaca      720

ctggccacct cttacagcag cggagattac accgaccaga gaatcacgag cgctgacctg      780

cacaatgact gcacggagac gcacacaggc acctcggcct ctgcacctct ggctgctggc      840

atcttcgctc tggccctgga agcaaaccca aatctcacct ggcgagatat gcagcacctg      900

gttgtctgga cctctgagta tgacccgctg gccaataacc ctggatggaa aaagaatgga      960

gcaggcttga tggtgaatag tcgatttgga tttggcttgc taaatgccaa agctctggtg     1020

gatttagctg accccaggac ctggaggagc gtgcctgaga agaaagagtg tgttgtaaag     1080

gacaatgact ttgagcccag agccctgaaa gctaatggag aagttatcat tgaaattcca     1140

acaagagctt gtgaaggaca agaaaatgct atcaagtccc tggagcatgt acaatttgaa     1200

gcaacaattg aatattcccg aagaggagac cttcatgtca cacttacttc tgctgctgga     1260

actagcactg tgctcttggc tgaaagagaa cgggatacat ctcctaatgg ctttaagaat     1320

tgggacttca tgtctgttca cacatgggga gagaacccta taggtacttg gactttgaga     1380

attacagaca tgtctggaag aattcaaaat gaaggaagaa ttgtgaactg gaagctgatt     1440

ttgcacggga cctcttctca gccagagcat atgaagcagc ctcgtgtgta cacgtcctac     1500

aacactgttc agaatgacag aagaggggtg gagaagatgg tggatccagg ggaggagcag     1560

cccacacaag agaaccctaa ggagaacacc ctggtgtcca aaagccccag cagcagcagc     1620

gtagggggcc ggagggatga gttggaggag ggagcccctt ccgaggccat gctgcgactc     1680

ctgcaaagtg ctttcagtaa aaactcaccg ccaaagcaat caccaaagaa gtccccaact     1740

gcaaagctca acatccctta tgaaaacttc tacgaagccc tggaaaagct gaacaaacct     1800

tcccagctta aagactctga agacagtctg tataatgact atgttgatgt tttttataac     1860

actaaacctt acaagcacag agacgaccgg ctgcttcaag ctctggtgga cattctgaat     1920

gaggaaaat                                                             1929


<210>  5274
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  5274
cagaactgca gcgggccgtg ccggtgcccg gacgagccgg cgccgcgctg cccggcgggc       60

gtgagcctcg tgctggacgg ctgcggctgc tgccgcgtct gcgccaagca gctgggcgag      120

ctgtgcaccg agcgcgaccc ctgcgacccg cacaagggcc tcttctgtga cttcggctcc      180

ccggccaacc gcaagatcgg cgtgtgcacc gccaaagatg gtgctccctg catcttcggt      240

ggtacggtgt accgcagcgg agagtccttc cagagcagct gcaagtacca gtgcacgtgc      300

ctggacgggg cggtgggctg catgcccctg tgcagcatgg acgttcgtct gcccagccct      360

gactgcccct tcccgaggag ggtcaagctg cccgggaaat gctgcgagga gtgggtgtgt      420

gacgagccca aggaccaaac cgtggttggg cctgccctcg cggcttaccg actggaagac      480

acgtttggcc cagacccaac tatgattaga gccaactgcc tggtccagac cacagagtgg      540

agcgcctgtt ccaagacctg tgggatgggc atctccaccc gggttaccaa tgacaacgcc      600

tcctgcaggc tagagaagca gagccgcctg tgcatggtca ggccttgcga agctgacctg      660

gaagagaaca ttaagaaggg caaaaagtgc atccgtactc ccaaaatctc caagcctatc      720

aagtttgagc tttctggctg caccagcatg aagacatacc gagctaaatt ctgtggagta      780

tgtaccgacg gccgatgctg caccccccac agaaccacca ccctgccggt ggagttcaag      840

tgccctgacg gcgaggtcat gaagaagaac atgatgttca tcaagacctg tgcctgccat      900

tacaactgtc ccggagacaa tgacatcttt gaatcgctgt actacaggaa gatgtacgga      960

gacatggca                                                              969


<210>  5275
<211>  1221
<212>  DNA
<213>  Homo Sapiens

<400>  5275
cagctgcacg ttgagcatga tggtgagagt tgcagtaaca gctcccacca gcagattctg       60

gagacaggtg agggctcccc cagcctcaag atagcccctg ccaatgctga ctttgccttc      120

cgcttctact acctgatcgc ttcggagacc ccggggaaga acatcttttt ctccccgctg      180

agcatctcgg cggcctacgc catgctttcc ctgggggcct gctcacacag ccgcagccag      240

atccttgagg gcctgggctt caacctcacc gagctgtctg agtccgatgt ccataggggc      300

ttccagcacc tcctgcacac tctcaacctc cccggccatg ggctggaaac acgcgtgggc      360

agtgctctgt tcctgagcca caacctgaag ttccttgcaa aattcctgaa tgacaccatg      420

gccgtctatg aggctaaact cttccacacc aacttctacg acactgtggg cacaatccag      480

cttatcaacg accacgtcaa gaaggaaact cgagggaaga ttgtggattt ggtcagtgag      540

ctcaagaagg acgtcttgat ggtgctggtg aattacattt acttcaaagc cctgtgggag      600

aaaccattca tttcctcaag gaccactccc aaagactttt atgttgatga gaacacaaca      660

gtccgggtgc ccatgatgct gcaggaccag gagcatcact ggtatcttca tgacagatac      720

ttgccctgct cggtgctacg gatggattac aaaggagacg caaccgtgtt tttcattctc      780

cctaaccaag gcaaaatgag ggagattgaa gaggttctga ctccagagat gctaatgagg      840

tggaacaact tgttgcggaa gaggaatttt tacaagaagc tagagttgca tcttcccaag      900

ttctccattt ctggctccta tgtattagat cagattttgc ccaggctggg cttcacggat      960

ctgttctcca agtgggctga cttatccggc atcaccaaac agcaaaaact ggaggcatcc     1020

aaaagtttcc acaaggccac cttggacgtg gatgaggctg gcaccgaggc tgcagcagcc     1080

accagcttcg cgatcaaatt cttctctgcc cagaccaatc gccacatcct gcgattcaac     1140

cggcccttcc ttgtggtgat cttttccacc agcacccaga gtgtcctctt tctgggcaag     1200

gtcgtcgacc ccacgaaacc a                                               1221


<210>  5276
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  5276
aacataggtt ctatgatttc caacatgaat gcagccagag cagaatttca agcaagaatt       60

gatgctatca agcaatatat gcattttcga aatgtaagca aagatatgga aaagagggtt      120

attaaatggt ttgactacct gtggaccaac aaaaaaacag ttgatgagaa agaagtctta      180

aagtatctac ctgataaact aagagcagaa attgccatca acgttcactt agacacatta      240

aaaaaggtac gc                                                          252


<210>  5277
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  5277
ctgcacacca agggcgccct tcccctggat acggtcactt tctacaaggt cattcccaaa       60

agcaagttcg tcttggtgaa gttcgacacc cagtacccct acggtgagaa gcaggatgag      120

ttcaagcgtc ttgctgaaaa ctcggcttcc agcgatgatc tcttggtggc agaggtgggg      180

atctcagatt atggtgacaa gctgaacatg gagctgagtg agaaatacaa gctggacaaa      240

gagagctacc cagtcttcta cctcttccgg gatggggact ttgagaaccc agtcccatac      300

actggggcag ttaaggttgg agccatccag cgctggctga aggggcaagg ggtctaccta      360

ggtatgcctg gttgcctgcc tgtatacgac gccctggccg gggagttcat cagggcctct      420

ggtgtggagg cccgccaggc cctcttgaag caggggcaag ataacctctc aagtgtgaag      480

gagactcaga agaagtgggc cgagcaatac ctgaagatca tggggaagat cttagaccaa      540

ggggaggact tcccagcatc agagatgaca cggatcgcca ggctgattga gaagaacaag      600

atgagtgacg ggaagaagga ggagctccag aagagcttaa acatcctgac tgccttccag      660

aagaaggggg ccgagaaaga ggagctg                                          687


<210>  5278
<211>  1443
<212>  DNA
<213>  Homo Sapiens

<400>  5278
tccgacgtgc tagaactcac ggacgacaac ttcgagagtc gcatctccga cacgggctct       60

gcgggcctca tgctcgtcga gttcttcgcc ccctggtgtg gacactgcaa gagacttgca      120

cctgagtatg aagctgcagc taccagatta aaaggaatag tcccattagc aaaggttgat      180

tgcactgcca acactaacac ctgtaataaa tatggagtca gtggatatcc aaccctgaag      240

atatttagag atggtgaaga agcaggtgct tatgatggac ctaggactgc tgatggaatt      300

gtcagccact tgaagaagca ggcaggacca gcttcagtgc ctctcaggac tgaggaagaa      360

tttaagaaat tcattagtga taaagatgcc tctatagtag gttttttcga tgattcattc      420

agtgaggctc actccgagtt cctaaaagca gccagcaact tgagggataa ctaccgattt      480

gcacatacga atgttgagtc tctggtgaac gagtatgatg ataatggaga gggtatcatc      540

ttatttcgtc cttcacatct cactaacaag tttgaggaca agactgtggc atatacagag      600

caaaaaatga ccagtggcaa aattaaaaag tttatccagg aaaacatttt tggtatctgc      660

cctcacatga cagaagacaa taaagatttg atacagggca aggacttact tattgcttac      720

tatgatgtgg actatgaaaa gaacgctaaa ggttccaact actggagaaa cagggtaatg      780

atggtggcaa agaaattcct ggatgctggg cacaaactca actttgctgt agctagccgc      840

aaaaccttta gccatgaact ttctgatttt ggcttggaga gcactgctgg agagattcct      900

gttgttgcta tcagaactgc taaaggagag aagtttgtca tgcaggagga gttctcgcgt      960

gatgggaagg ctctggagag gttcctgcag gattactttg atggcaatct gaagagatac     1020

ctgaagtctg aacctatccc agagagcaat gatgggcctg tgaaggtagt ggtagcagag     1080

aattttgatg aaatagtgaa taatgaaaat aaagatgtgc tgattgaatt ttatgcccct     1140

tggtgtggtc actgtaagaa cctggagccc aagtataaag aacttggcga gaagctcagc     1200

aaagacccaa atatcgtcat agccaagatg gatgccacag ccaatgatgt gccttctcca     1260

tatgaagtca gaggttttcc taccatatac ttctctccag ccaacaagaa gctaaatcca     1320

aagaaatatg aaggtggccg tgaattaagt gattttatta gctatctaca aagagaagct     1380

acaaaccccc ctgtaattca agaagaaaaa cccaagaaga agaagaaggc acaggaggat     1440

ctc                                                                   1443


<210>  5279
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  5279
tcctgggcca tttactacct gtacaactcc ttcaccacga cactgccgtg gaaacagtgc       60

gacaacccct ggaacacaga ccgctgcttc tccaactaca gcatggtcaa cactaccaac      120

atgaccagcg ctgtggtgga gttctgggag cgcaacatgc atcagatgac ggacgggctg      180

gataagccag gtcagatccg c                                                201


<210>  5280
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  5280
cgctgcggtc tagcgggcgc ggcgggcggc gcgcagagag gattatctga accttcttct       60

attgcaaaac atgaagatag tttgcttaag gatttatttc aagactacga aagatgggtt      120

cgtcctgtgg aacacctgaa tgacaaaata aaaataaaat ttggacttgc aatatctcaa      180

ttggtggatg tggatgagaa aaatcagtta atgacaacaa acgtctggtt gaaacaggaa      240

tggatagatg taaaattaag atggaaccct gatgactatg gtggaataaa agttatacgt      300

gttccttcag actctgtctg gacaccagac atcgttttgt ttgataatgc agatggacgt      360

tttgaaggga ccagtacgaa aacagtcatc aggtacaatg gcactgtcac ctggactcca      420

ccggcaaact acaaaagttc ctgtaccata gatgtcacgt ttttcccatt tgaccttcag      480

aactgttcca tgaaatttgg ttcttggact tatgatggat cacaggttga tataattcta      540

gaggaccaag atgtagacaa gagagatttt tttgataatg gagaatggga gattgtgagt      600

gcaacaggga gcaaaggaaa cagaaccgac agctgttgct ggtatccgta tgtcacttac      660

tcatttgtaa tcaagcgcct gcctctcttt tatacc                                696


<210>  5281
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  5281
tactcgcggg agaagaacca gcccaagccg tccccgaaac gcgagtccgg agaggagttc       60

cgcatggaga agttgaacca gctgtgggag aaggcccagc gactgcatct tcctcccgtg      120

aggctggccg agctccacgc tgatctgaag atacaggaga gggacgaact cgcctggaag      180

aaactaaagc ttgacggctt ggacgaagat ggggagaagg aagcgagact catacgcaac      240

ctcaatgtca tcttggccaa gtatggtctg gacggaaaga aggacgctcg gcaggtgacc      300

agcaactccc tcagtggcac ccaggaagac gggctggatg accccaggct ggaaaagctg      360

tggcacaagg cgaagacctc tgggaaattc tccggcgaag aactggacaa gctctggcgg      420

gagttcctgc atcacaaaga gaaagttcac gagtacaacg tcctgctgga gaccctgagc      480

aggaccgaag aaatccacga gaacgtcatt agcccctcgg acctgagcga catcaagggc      540

agcgtcctgc acagcaggca cacggagctg aaggagaagc tgcgcagcat caaccagggc      600

ctggaccgcc tgcgcagggt cagccaccag ggctacagca ctgaggctga gttcgaggag      660

cccagggtga ttgacctgtg ggacctggcg cagtccgcca acctcacgga caaggagctg      720

gaggcgttcc gggaggagct caagcacttc gaagccaaaa tcgagaagca caaccactac      780

cagaagcagc tggagattgc gcacgagaag ctgaggcacg cagagagcgt gggcgacggc      840

gagcgtgtga gccgcagccg cgagaagcac gccctgctgg aggggcggac caaggagctg      900

ggctacacgg tgaagaagca tctgcaggac ctgtccggca ggatctccag agctcggcac      960

aacgaactc                                                              969


<210>  5282
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  5282
cgcgtggcca atgcggagga aaagctgatg gacgaccttc tgaacaaaac ccgttacaat       60

aacctgatcc gcccagccac cagctcctca cagctcatct ccatcaagct gcagctctcc      120

ctggcccagc ttatcagcgt gaatgagcga gagcagatca tgaccaccaa tgtctggctg      180

aaacaggaat ggactgatta ccgcctgacc tggaacagct cccgctacga gggtgtgaac      240

atcctgagga tccctgcaaa gcgcatctgg ttgcctgaca tcgtgcttta caacaacgcc      300

gacgggacct atgaggtgtc tgtctacacc aacttgatag tccggtccaa cggcagcgtc      360

ctgtggctgc cccctgccat ctacaagagc gcctgcaaga ttgaggtgaa gtactttccc      420

ttcgaccagc agaactgcac cctcaagttc cgctcctgga cctatgacca cacggagata      480

gacatggtcc tcatgacgcc cacagccagc atggatgact ttactcccag tggtgagtgg      540

gacatagtgg ccctcccagg gagaaggaca gtgaacccac aagaccccag ctacgtggac      600

gtgacttacg acttcatcat caagcgcaag cctctgttct acacc                      645


<210>  5283
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  5283
tcagattcag aagaggaaat gaaagcatta gaagcagatt tcttgaccaa tatgcataca       60

tcaaagatta gtaaagcaca tgttccctct tggaagatga ctctgctaaa tgtttgcagt      120

cttgtaaata atttgaacag cccagctgag gaaacaggag aagttcatga agaggagctt      180

gttgcaagaa ggaaacttcc tactgcttta gatggcttta gcttggaagc aatgttgaca      240

atataccagc tccacaaaat ctgtcacagc agggcttttc aacactggga gttaatccag      300

gaagatattc ttgatactgg aaatgacaaa aatggaaagg aagaagtcat aaagagaaaa      360

attccttata ttctg                                                       375


<210>  5284
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  5284
agcaacactc aagctgagag gtccataata ggcatgatcg acatgtttca caaatacacc       60

agacgtgatg acaagattga caagccaagc ctgctgacga tgatgaagga gaacttcccc      120

aacttcctta gtgcctgtga caaaaagggc acaaattacc tcgccgatgt ctttgagaaa      180

aaggacaaga atgaggataa gaagattgat ttttctgagt ttctgtcctt gctgggagac      240

atagccacag actaccacaa gcagagccat ggagcagcgc cctgttccgg gggcagccag      300


<210>  5285
<211>  1086
<212>  DNA
<213>  Homo Sapiens

<400>  5285
caggaagggc tggacttccc tgagtacgat ggtgtggacc gtgtgatcaa tgtcaatgca       60

aagaactaca agaatgtgtt caagaagtat gaggtgctgg cactcctcta ccatgaaccc      120

cccgaggatg acaaggcctc acaaagacaa tttgagatgg aggagctgat cctggagtta      180

gcagcccaag tcctagaaga caagggtgtt ggcttcgggc tggtagactc tgagaaggat      240

gcagctgtgg ccaagaaact aggcctaact gaagtggaca gcatgtatgt attcaaggga      300

gatgaagtca ttgagtacga tggcgagttt tctgctgaca ccatcgtgga gtttctgctt      360

gatgtcctag aggaccctgt ggaattgatt gaaggtgaac gagagctgca ggcgtttgag      420

aatattgagg atgagatcaa actcattggc tacttcaaga gcaaagactc agagcattac      480

aaagccttcg aggatgcagc tgaggagttt catccctaca tccccttctt cgccaccttc      540

gacagcaagg tggcaaagaa gctgaccctg aagctgaatg agattgattt ctacgaggcc      600

ttcatggaag agcctgtgac catcccagac aagcccaata gcgaagagga gattgtcaac      660

ttcgtggagg agcacaggag atcaaccctg aggaaactga agccggagag tatgtatgag      720

acctgggagg atgatatgga tggaatccac attgtggcct tcgcagagga agctgatcct      780

gatggtttcg agttcttaga gactctcaag gctgtggccc aagataacac tgaaaaccca      840

gatcttagca tcatctggat tgaccctgat gacttccccc tgctggtccc atactgggag      900

aagacgtttg acatcgactt gtcagcccca caaataggag tcgtcaatgt tactgatgcg      960

gatagcgtat ggatggaaat ggacgatgag gaggacctgc cttctgctga ggagctggag     1020

gactggctgg aggatgtcct ggagggcgag atcaacacag aggacgatga cgatgatgat     1080

gatgac                                                                1086


<210>  5286
<211>  684
<212>  DNA
<213>  Homo Sapiens

<400>  5286
cagatgccaa ccagttcagt gaaagatgag accaatgaca acatcacgat atttaccagg       60

atcttggatg ggctcttgga tggctacgac aacagacttc ggcccgggct gggagagcgc      120

atcactcagg tgaggaccga catctacgtc accagcttcg gcccggtgtc cgacacggaa      180

atggagtaca ccatagacgt gtttttccga caaagctgga aagatgaaag gcttcggttt      240

aaggggccca tgcagcgcct ccctctcaac aacctccttg ccagcaagat ctggacccca      300

gacacgttct tccacaacgg gaagaagtcc atcgctcaca acatgaccac gcccaacaag      360

ctgctgcggc tggaggacga cggcaccctg ctctacacca tgcgcttgac catctctgca      420

gagtgcccca tgcagcttga ggacttcccg atggatgcgc acgcttgccc tctgaaattt      480

ggcagctatg cgtaccctaa ttctgaagtc gtctacgtct ggaccaacgg ctccaccaag      540

tcggtggtgg tggcggaaga tggctccaga ctgaaccagt accacctgat ggggcagacg      600

gtgggcactg agaacatcag caccagcaca ggcgaataca caatcatgac agctcacttc      660

cacctgaaaa ggaagattgg ctac                                             684


<210>  5287
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  5287
atggagagag ccagtctgat ccagaaggcc aagctggcag agcaggccga acgctatgag       60

gacatggcag ccttcatgaa aggcgccgtg gagaagggcg aggagctctc ctgcgaagag      120

cgaaacctgc tctcagtagc ctataagaac gtggtgggcg gccagagggc tgcctggagg      180

gtgctgtcca gtattgagca gaaaagcaac gaggagggct cggaggagaa ggggcccgag      240

gtgcgtgagt accgggagaa ggtggagact gagctccagg gcgtgtgcga caccgtgctg      300

ggcctgctgg acagccacct catcaaggag gccggggacg ccgagagccg ggtcttctac      360

ctgaagatga agggtgacta ctaccgctac ctggccgagg tggccaccgg tgacgacaag      420

aagcgcatca ttgactcagc ccggtcagcc taccaggagg ccatggacat cagcaagaag      480

gagatgccgc ccaccaaccc catccgcctg ggcctggccc tgaacttttc cgtcttccac      540

tacgagatcg ccaacagccc cgaggaggcc atctctctgg ccaagaccac tttcgacgag      600

gccatggctg atctgcacac cctcagcgag gactcctaca aagacagcac cctcatcatg      660

cagctgctgc gagacaacct gacactgtgg acggccgaca acgccgggga agaggggggc      720

gaggctcccc aggagcccca gagc                                             744


<210>  5288
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  5288
tcagaggctg agcaccgtct atttgagcgg ctgtttgaag attacaatga gatcatccgg       60

cctgtagcca acgtgtctga cccagtcatc atccatttcg aggtgtccat gtctcagctg      120

gtgaaggtgg atgaagtaaa ccagatcatg gagaccaacc tgtggctcaa gcaaatctgg      180

aatgactaca agctgaagtg gaacccctct gactatggtg gggcagagtt catgcgtgtc      240

cctgcacaga agatctggaa gccagacatt gtgctgtata acaatgctgt tggggatttc      300

caggtggacg acaagaccaa agccttactc aagtacactg gggaggtgac ttggatacct      360

ccggccatct ttaagagctc ctgtaaaatc gacgtgacct acttcccgtt tgattaccaa      420

aactgtacca tgaagttcgg ttcctggtcc tacgataagg cgaaaatcga tctggtcctg      480

atcggctctt ccatgaacct caaggactat tgggagagcg gcgagtgggc catcatcaaa      540

gccccaggct acaaacacga catcaagtac aactgctgcg aggagatcta ccccgacatc      600

acatactcgc tgtacatccg gcgcctg                                          627


<210>  5289
<211>  1767
<212>  DNA
<213>  Homo Sapiens

<400>  5289
atggcatcag agatccacat gacaggccca atgtgcctca ttgagaacac taatgggcga       60

ctgatggcga atccagaagc tctgaagatc ctttctgcca ttacacagcc tatggtggtg      120

gtggcaattg tgggcctcta ccgcacaggc aaatcctacc tgatgaacaa gctggctgga      180

aagaaaaagg gcttctctct gggctccacg gtgcagtctc acactaaagg aatctggatg      240

tggtgtgtgc cccaccccaa gaagccaggc cacatcctag ttctgctgga caccgagggt      300

ctgggagatg tagagaaggg tgacaaccag aatgactcct ggatcttcgc cctggccgtc      360

ctcctgagca gcaccttcgt gtacaatagc ataggaacca tcaaccagca ggctatggac      420

caactgtact atgtgacaga gctgacacat agaatccgat caaaatcctc acctgatgag      480

aatgagaatg aggttgagga ttcagctgac tttgtgagct tcttcccaga ctttgtgtgg      540

acactgagag atttctccct ggacttggaa gcagatggac aacccctcac accagatgag      600

tacctgacat actccctgaa gctgaagaaa ggtaccagtc aaaaagatga aacttttaac      660

ctgcccagac tctgtatccg gaaattcttc ccaaagaaaa aatgctttgt ctttgatcgg      720

cccgttcacc gcaggaagct tgcccagctc gagaaactac aagatgaaga gctggacccc      780

gaatttgtgc aacaagtagc agacttctgt tcctacatct ttagtaattc caaaactaaa      840

actctttcag gaggcatcca ggtcaacggg cctcgtctag agagcctggt gctgacctac      900

gtcaatgcca tcagcagtgg ggatctgccg tgcatggaga acgcagtcct ggccttggcc      960

cagatagaga actcagctgc agtgcaaaag gctattgccc actatgaaca gcagatgggc     1020

cagaaggtgc agctgcccac agaaagcctc caggagctgc tggacctgca cagggacagt     1080

gagagagagg ccattgaagt cttcatcagg agttccttca aagatgtgga ccatctattt     1140

caaaaggagt tagcggccca gctagaaaaa aagcgggatg acttttgtaa acagaatcag     1200

gaagcatcat cagatcgttg ctcaggttta cttcaggtca ttttcagtcc tctagaagaa     1260

gaagtgaagg cgggaattta ttcgaaacca gggggctatc gtctctttgt tcagaagcta     1320

caagacctga agaaaaagta ctatgaggaa ccgaggaagg ggatacaggc tgaagagatt     1380

ctgcagacat acttgaaatc caaggagtct atgactgatg caattctcca gacagaccag     1440

actctcacag aaaaagaaaa ggagattgaa gtggaacgtg tgaaagctga gtctgcacag     1500

gcttcagcaa aaatgttgca ggaaatgcaa agaaagaatg agcagatgat ggaacagaag     1560

gagaggagtt atcaggaaca cttgaaacaa ctgactgaga agatggagaa cgacagggtc     1620

cagttgctga aagagcaaga gaggaccctc gctcttaaac ttcaggaaca ggagcaacta     1680

ctaaaagagg gatttcaaaa agaaagcaga ataatgaaaa atgagataca ggatctccag     1740

acgaaaatga gacgacgaaa ggcatgt                                         1767


<210>  5290
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  5290
gccccgcagc cccccaacat cctgctcctg ctcatggacg acatgggatg gggtgacctc       60

ggggtgtatg gagagccctc cagagagacc ccgaatttgg accggatggc tgcagaaggg      120

ctgcttttcc caaacttcta ttctgccaac cctctgtgct cgccatcgag ggcggcactg      180

ctcacaggac ggctacccat ccgcaatggc ttctacacca ccaacgccca tgccagaaac      240

gcctacacac cgcaggagat tgtgggcggc atcccagact cggagcagct cctgccggag      300

cttctgaaga aggccggcta cgtcagcaag attgtcggca agtggcatct gggtcacagg      360

ccccagttcc accccctgaa gcacggattt gatgagtggt ttggatcccc caactgccac      420

tttggacctt atgacaacaa ggccaggccc aacatccctg tgtacaggga ctgggagatg      480

gttggcagat attatgaaga atttcctatt aatctgaaga cgggggaagc caacctcacc      540

cagatctacc tgcaggaagc cctggacttc attaagagac aggcacggca ccaccccttt      600

ttcctctact gggctgtcga cgccacgcac gcacccgtct atgcctccaa acccttcttg      660

ggcaccagtc agcgagggcg gtatggagac gccgtccggg agattgatga cagcattggg      720

aagatactgg agctcctcca agacctgcac gtcgcggaca acaccttcgt cttcttcacg      780

tcggacaacg gcgctgccct catttccgcc cccgaacaag gtggcagcaa cggccccttt      840

ctgtgtggga agcagaccac gtttgaagga gggatgaggg agcctgccct cgcatggtgg      900

ccagggcacg tcactgcagg ccaggtgagc caccagctgg gcagcatcat ggacctcttc      960

accaccagcc tggcccttgc gggcctgacg ccgcccagcg acagggccat tgatggcctc     1020

aacctcctcc ccaccctcct gcagggccgg ctgatggaca ggcctatctt ctattaccgt     1080

ggcgacacgc tgatggcggc caccctcggg cagcacaagg ctcacttctg gacctggacc     1140

aactcctggg agaacttcag acagggcatt gatttctgcc ctgggcagaa cgtttcaggg     1200

gtcacaactc acaatctgga agaccacacg aagctgcccc tgatcttcca cctgggacgg     1260

gacccagggg agaggttccc cctcagcttt gccagcgccg agtaccagga ggccctcagc     1320

aggatcacct cggtcgtcca gcagcaccag gaggccttgg tccccgcgca gccccagctc     1380

aacgtgtgca actgggcggt catgaactgg gcacctccgg gctgtgaaaa gttagggaag     1440

tgtctgacac ctccagaatc cattcccaag aagtgcctct ggtcccac                  1488


<210>  5291
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  5291
caggatggca tgtaccagcg attcctgcgg caacacgtgc accctgagga gacaggtggc       60

agtgatcgct actgcaactt gatgatgcaa agacggaaga tgactttgta tcactgcaag      120

cgcttcaaca ccttcatcca tgaagatatc tggaacattc gtagtatctg cagcaccacc      180

aatatccaat gcaagaacgg caagatgaac tgccatgagg gtgtagtgaa ggtcacagat      240

tgcagggaca caggaagttc cagggcaccc aactgcagat atcgggccat agcgagcact      300

agacgtgttg tcattgcctg tgagggtaac ccacaggtgc ctgtgcactt tgacggt         357


<210>  5292
<211>  894
<212>  DNA
<213>  Homo Sapiens

<400>  5292
aatgactgtc ctcacaaaaa atcagctact ttgctgccat ccttcacggt gacacccacg       60

gttacagaga gcactggaac aaccagccac aggactacca agagccacaa aaccaccact      120

cacaggacaa ccaccacagg caccaccagc cacggaccca cgactgccac tcacaacccc      180

accaccacca gccatggaaa cgtcacagtt catccaacaa gcaatagcac tgccaccagc      240

cagggaccct caactgccac tcacagtcct gccaccacta gtcatggaaa tgccacggtt      300

catccaacaa gcaacagcac tgccaccagc ccaggattca ccagttctgc ccacccagaa      360

ccacctccac cctctccgag tcctagccca acctccaagg agaccattgg agactacacg      420

tggaccaatg gttcccagcc ctgtgtccac ctccaagccc agattcagat tcgagtcatg      480

tacacaaccc agggtggagg agaggcctgg ggcatctctg tactgaaccc caacaaaacc      540

aaggtccagg gaagctgtga gggtgcccat ccccacctgc ttctctcatt cccctatgga      600

cacctcagct ttggattcat gcaggacctc cagcagaagg ttgtctacct gagctacatg      660

gcggtggagt acaatgtgtc cttcccccac gcagcacagt ggacattctc ggctcagaat      720

gcatcccttc gagatctcca agcacccctg gggcagagct tcagttgcag caactcgagc      780

atcattcttt caccagctgt ccacctcgac ctgctctccc tgaggctcca ggctgctcag      840

ctgccccaca caggggtctt tgggcaaagt ttctcctgcc ccagtgaccg gtcc            894


<210>  5293
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  5293
caaggggaat caagacgaca agaacccggg gactttgtga agcaggacat tggcgggctg       60

tctcctaagc atgccccaga tattcctgat gacagcactg acaacatcac tatcttcacc      120

agaatcttgg atcgtcttct ggacggctat gacaaccggc tgcgacctgg gcttggagat      180

gcagtgactg aagtgaagac tgacatctac gtgaccagtt ttggccctgt gtcagacact      240

gacatggagt acactattga tgtatttttt cggcagacat ggcatgatga aagactgaaa      300

tttgatggcc ccatgaagat ccttccactg aacaatctcc tggctagtaa gatctggaca      360

ccggacacct tcttccacaa tggcaagaaa tcagtggctc ataacatgac cacgcccaac      420

aagctgctca gattggtgga caacggaacc ctcccctata caatgaggtt aacaattcat      480

gctgagtgtc ccatgcattt ggaagatttt cccatggatg tgcatgcctg cccactgaag      540

tttggaagct atgcctatac aacagctgaa gtggtttatt cttggactct cggaaagaac      600

aaatccgtgg aagtggcaca ggatggttct cgcttgaacc agtatgacct tttgggccat      660

gttgttggga cagagataat ccggtctagt acaggagaat atgtcgtcat gacaacccac      720

ttccatctca agcgaaaaat tggc                                             744


<210>  5294
<211>  543
<212>  DNA
<213>  Homo Sapiens

<400>  5294
aagacagaga caattacaac agagaagcag tcacagccta ccttattcac atcatcaatg       60

tcacaggtat tggctaattc tcaaaacaca acagggaatc ctttgggtca accaacacaa      120

ttcagcgaca ctttttctgg acaatcaata tcacctgcca aagtcactgc tggacaacca      180

acaccagctg tctatacctc ttctgaaaaa ccagaagcac atacttctgc tggacaacca      240

cttgcctaca acaccaaaca accaacacca atagccaaca cctcctccca gcaagccgtg      300

ttcacctctg ccagacaact accatctgcc cgtacttcta ccacacaacc accaaagtca      360

tttgtctata cttttactca acaatcatca tctgtccaga tcccttctag aaaacaaata      420

actgttcata atccatccac acaaccaaca tcaactgtca aaaattcacc taggagtaca      480

ccaggattta tcttagatac taccagtaac aaacaaaccc cacaaaaaaa caattataat      540

tca                                                                    543


<210>  5295
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  5295
ccgccgccgc tgctgcttct gcttgcgctg ttgccgctgc tgcccgcgcc tggcgctgcc       60

gccgcccccg ccccgcggcc cccggagctg cagtcggctt ccgcggggcc cagcgtgagt      120

ctctacctga gcgaggacga ggtgcgccgg ctgatcggtc ttgatgcaga actttattat      180

gtgagaaatg accttattag tcactacgct ctatccttta gtctgttagt acccagtgag      240

acaaatttcc tgcacttcac ctggcatgcg aagtccaagg ttgaatataa gctgggattc      300

caagtggaca atgttttggc aatggatatg ccccaggtca acatttctgt tcagggggaa      360

gttccacgca ctttatcagt gtttcgggta gagctttcct gtactggcaa agtagattct      420

gaagttatga tactaatgca gctcaacttg acagtaaatt cttcaaaaaa ttttaccgtc      480

ttaaatttta aacgaaggaa aatgtgctac aaaaaacttg aagaagtaaa aacttcagcc      540

ttggacaaaa acactagcag aactatttat gatcctgtac atgcagctcc aaccacttct      600

acgcgt                                                                 606


<210>  5296
<211>  1521
<212>  DNA
<213>  Homo Sapiens

<400>  5296
gacccggcca gcaagagccg gagctgcggc gaggtccgcc agatctacgg agccaagggc       60

ttcagcctga gcgacgtgcc ccaggcggag atctcgggtg agcacctgcg gatctgtccc      120

cagggctaca cctgctgcac cagcgagatg gaggagaacc tggccaaccg cagccatgcc      180

gagctggaga ccgcgctccg ggacagcagc cgcgtcctgc aggccatgct tgccacccag      240

ctgcgcagct tcgatgacca cttccagcac ctgctgaacg actcggagcg gacgctgcag      300

gccaccttcc ccggcgcctt cggagagctg tacacgcaga acgcgagggc cttccgggac      360

ctgtactcag agctgcgcct gtactaccgc ggtgccaacc tgcacctgga ggagacgctg      420

gccgagttct gggcccgcct gctcgagcgc ctcttcaagc agctgcaccc ccagctgctg      480

ctgcctgatg actacctgga ctgcctgggc aagcaggccg aggcgctgcg gcccttcggg      540

gaggccccga gagagctgcg cctgcgggcc acccgtgcct tcgtggctgc tcgctccttt      600

gtgcagggcc tgggcgtggc cagcgacgtg gtccggaaag tggctcaggt ccccctgggc      660

ccggagtgct cgagagctgt catgaagctg gtctactgtg ctcactgcct gggagtcccc      720

ggcgccaggc cctgccctga ctattgccga aatgtgctca agggctgcct tgccaaccag      780

gccgacctgg acgccgagtg gaggaacctc ctggactcca tggtgctcat caccgacaag      840

ttctggggta catcgggtgt ggagagtgtc atcggcagcg tgcacacgtg gctggcggag      900

gccatcaacg ccctccagga caacagggac acgctcacgg ccaaggtcat ccagggctgc      960

gggaacccca aggtcaaccc ccagggccct gggcctgagg agaagcggcg ccggggcaag     1020

ctggccccgc gggagaggcc accttcaggc acgctggaga agctggtctc tgaagccaag     1080

gcccagctcc gcgacgtcca ggacttctgg atcagcctcc cagggacact gtgcagtgag     1140

aagatggccc tgagcactgc cagtgatgac cgctgctgga acgggatggc cagaggccgg     1200

tacctccccg aggtcatggg tgacggcctg gccaaccaga tcaacaaccc cgaggtggag     1260

gtggacatca ccaagccgga catgaccatc cggcagcaga tcatgcagct gaagatcatg     1320

accaaccggc tgcgcagcgc ctacaacggc aacgacgtgg acttccagga cgccagtgac     1380

gacggcagcg gctcgggcag cggtgatggc tgtctggatg acctctgcgg ccggaaggtc     1440

agcaggaaga gctccagctc ccggacgccc ttgacccatg ccctcccagg cctgtcagag     1500

caggaaggac agaagacctc g                                               1521


<210>  5297
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  5297
gggaaggtgc tggtggtgcc cactgatggc agccactggc tcagcatgcg ggaggccttg       60

cgggacctcc atgcgagagg ccaccaggtg gtggtcctca ccctggaggt gaatatgtac      120

atcaaagaag agaacttttt caccctgaca acgtatgcca tttcatggac ccaggacgaa      180

tttgatcgcc ttttgctggg tcacactcaa tcgttctttg aaacagaaca tcttctgatg      240

aaattttcta gaagaatggc aattatgaac aatatgtctt tgatcataca taggtcttgt      300

gtggagctac tgcataatga ggccctgatc aggcacctgc atgctacttc ctttgatgtg      360

gttctaacag acccctttca cctctgcgcg gcggtgctgg ctaagtacct gtcgattcct      420

gctgtgtttt tcttgaggaa cattccatgt gatttagact ttaagggcac acagtgtcca      480

aacccttcct cctatattcc tagattacta acgaccaatt cagaccacat gacattcctg      540

caaagggtca agaacatgct ctaccctctg gccctgtcct acctttgcca tgctgtttct      600

gctccttatg caagccttgc ctctgagctt tttcagagag aggtgtcagt ggtggatctt      660

gtcagccatg catctgtgtg gctgttccga ggggactttg tgatggatta ccccaggccg      720

atcatgccca acatggtctt cattgggggc atcaactgtg ccaacgggaa gccactatct      780

caggaatttg aagcctacat taatgcttct ggagaacatg gaattgtggt tttctctttg      840

ggatcaatgg tctcagaaat tccagagaag aaagctatgg caattgctga tgctttgggc      900

aaaatccctc agacagtcct gtggcggtac actggaaccc gaccatcgaa tcttgcgaac      960

aacacgatac ttgttaagtg gctaccccaa aacgatctgc ttggtcaccc gatgacccgt     1020

gcctttatca cccatgctgg ttcccatggt gtttatgaaa gcatatgcaa tggcgttccc     1080

atggtgatga tgcccttgtt tggtgatcag atggacaatg caaagcgcat ggagactaag     1140

ggagctggag tgaccctgaa tgttctggaa atgacttctg aagatttaga aaatgctcta     1200

aaagcagtca tcaatgacaa aagttacaag gagaacatca tgcgcctctc cagccttcac     1260

aaggaccgcc cggtggagcc gctggacctg gccgtgttct gggtggagtt tgtgatgagg     1320

cacaagggcg cgccacacct gcgccccgca gcccacgacc tcacctggta ccagtaccat     1380

tccttggac                                                             1389


<210>  5298
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  5298
gaaagctggc gttcgttttt caaggaggct ctccaagggg ttggggacat gggcagagcc       60

tattgggaca taatgatatc caatcaccaa aattcaaaca gatatctcta tgctcgggga      120

aactatgatg ctgcccaaag aggacctggg ggtgtctggg ctgctaaact catcagccgt      180

tccagggtct atcttcaggg attaatagac tactatttat ttggaaacag cagcactgta      240

ttggaggact cgaagtccaa cgagaaagct gaggaatggg gccggagtgg caaagacccc      300

gaccgcttca gacctgacgg cctgcctaag aaatac                                336


<210>  5299
<211>  564
<212>  DNA
<213>  Homo Sapiens

<400>  5299
tgcacatgct cgcccagcca cccccaggac gccttctgca actccgacat cgtgatccgg       60

gccaaggtgg tggggaagaa gctggtaaag gaggggccct tcggcacgct ggtctacacc      120

atcaagcaga tgaagatgta ccgaggcttc accaagatgc cccatgtgca gtacatccat      180

acggaagctt ccgagagtct ctgtggcctt aagctggagg tcaacaagta ccagtacctg      240

ctgacaggtc gcgtctatga tggcaagatg tacacggggc tgtgcaactt cgtggagagg      300

tgggaccagc tcaccctctc ccagcgcaag gggctgaact atcggtatca cctgggttgt      360

aactgcaaga tcaagtcctg ctactacctg ccttgctttg tgacttccaa gaacgagtgt      420

ctctggaccg acatgctctc caatttcggt taccctggct accagtccaa acactacgcc      480

tgcatccggc agaagggcgg ctactgcagc tggtaccgag gatgggcccc cccggataaa      540

agcatcatca atgccacaga cccc                                             564


<210>  5300
<211>  1086
<212>  DNA
<213>  Homo Sapiens

<400>  5300
tacaaactgg tctgctacta caccagctgg tcccagtacc gggaaggcga tgggagctgc       60

ttcccagatg cccttgaccg cttcctctgt acccacatca tctacagctt tgccaatata      120

agcaacgatc acatcgacac ctgggagtgg aatgatgtga cgctctacgg catgctcaac      180

acactcaaga acaggaaccc caacctgaag actctcttgt ctgtcggagg atggaacttt      240

gggtctcaaa gattttccaa gatagcctcc aacacccaga gtcgccggac tttcatcaag      300

tcagtaccgc catttctgcg cacccatggc tttgatgggc tggaccttgc ctggctctac      360

cctggacgga gagacaaaca gcattttacc accctaatca aggaaatgaa ggccgaattt      420

ataaaggaag cccagccagg gaaaaagcag ctcctgctca gcgcagcact gtctgcgggg      480

aaggtcacca ttgacagcag ctatgacatt gccaagatat cccaacacct ggatttcatt      540

agcatcatga cctacgattt tcatggagcc tggcgtggga ccacaggcca tcacagtccc      600

ctgttccgag gtcaggagga tgcaagtcct gacagattca gcaacactga ctatgctgtg      660

gggtacatgt tgaggctggg ggctcctgcc agtaagctgg tgatgggcat ccccaccttc      720

gggaggagct tcactctggc ttcttctgag actggtgttg gagccccaat ctcaggaccg      780

ggaattccag gccggttcac caaggaggca gggacccttg cctactatga gatctgtgac      840

ttcctccgcg gagccacagt ccatagaatc ctcggccagc aggtccccta tgccaccaag      900

ggcaaccagt gggtaggata cgacgaccag gaaagcgtca aaagcaaggt gcagtacctg      960

aaggacaggc agctggcggg cgccatggta tgggccctgg acctggatga cttccagggc     1020

tccttctgcg gccaggatct gcgcttccct ctcaccaatg ccatcaagga tgcactcgct     1080

gcaacg                                                                1086


<210>  5301
<211>  1674
<212>  DNA
<213>  Homo Sapiens

<400>  5301
tctcgacacc aggccccatg tggcccccag gcctttgccc acgctgctgt tgccgccgac       60

tccaaggtct gctcggatat tggacgagcc atcctccagc agcagggctc acccgtggat      120

gccaccatcg cggctctggt ctgcaccagc gtcgtcaacc ctcagagcat gggcctgggc      180

ggaggggtca tcttcaccat ctacaatgtg acaacaggga aggtggaggt catcaatgcc      240

cgggagacgg tgccggccag ccacgccccg agcctgctgg accagtgtgc acaggctctg      300

ccactgggca caggggccca gtggatcggg gtgcccgggg agctccgtgg ctatgccgag      360

gcccaccgcc gccatggccg cctgccctgg gcgcagctgt tccagcccac catcgcgctg      420

ctccgagggg ggcatgtggt ggcccctgtc ctcagccgtt tcctgcacaa cagcatcctg      480

cggccttcct tgcaggcgtc aaccctgcgc cagctcttct tcaacgggac agaacccctg      540

aggcctcagg acccactccc atggcctgca ctggccacca ccctggagac cgtggccaca      600

gagggcgtgg aggtcttcta cacggggagg ctgggccaga tgctggtgga ggacattgcc      660

aaggaaggga gccagctgac gctgcaggac ctggccaagt tccagcccga ggtggtggat      720

gccctggagg tgcccctggg ggactatacc ctgtactcac caccgccgcc tgcagggggt      780

gccattctca gctttatcct caacgtgcta agagggttca acttctcaac agagtctatg      840

gccaggcctg aagggagggt gaacgtgtac caccaccttg tagagacgct caagtttgcc      900

aaggggcaga ggtggaggct gggggaccct cgaagccacc cgaagctcca gaatgcctcc      960

cgggacctgc tgggggagac cctggcccag ctcatccgcc aacagatcga tggccggggg     1020

gaccaccagc tcagccacta cagcttggcc gaggcctggg gccacgggac aggcacgtcc     1080

catgtgtctg tgctggggga ggatggcagc gccgtggctg ccaccagcac catcaacaca     1140

ccctttggag cgatggtgta ttcaccacgg acaggcatca tcctcaacaa cgagctcctg     1200

gacttatgcg agcgatgccc ccggggttcc ggcaccaccc cctcacctgc agtgagtgga     1260

gacagggtgg gtggagctcc cggaaggtgc tggcccccag ttccaggcga gcgttcccca     1320

tcctccatgg tgccctccat cttgatcaac aaagcccagg ggtcgaagct agtgattggc     1380

ggggctggcg gggagctcat catctctgct gtggcccagg ccatcatgag caagctgtgg     1440

cttggctttg acctgagagc ggccattgca gcccccatcc tgcatgtcaa cagcaagggc     1500

tgtgtggagt acgagcccaa cttcagccag gaggtgcaga ggggactcca agaccgtggc     1560

cagaaccaga cccagaggcc cttcttcctg aacgtggtcc aggctgtgtc ccaggagggg     1620

gcctgtgtgt acgccgtctc ggacctgagg aagagtgggg aggccgcagg ctac           1674


<210>  5302
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5302
tccgggcccc ggggggtcca ggctctgctg tgtgcgtgca ccagctgcct ccaggccaac       60

tacacgtgtg agacagatgg ggcctgcatg gtttccattt tcaatctgga tgggatggag      120

caccatgtgc gcacctgcat ccccaaagtg gagctggtcc ctgccgggaa gcccttctac      180

tgcctgagct cggaggacct gcgcaacacc cactgctgct acactgacta ctgcaacagg      240

atcgacttga gggtgcccag tggtcacctc aaggagcctg agcacccgtc catgtggggc      300

ccggtggag                                                              309


<210>  5303
<211>  1197
<212>  DNA
<213>  Homo Sapiens

<400>  5303
cagaaccctg ccagcccccc ggaggagggc tccccagacc ccgacagcac aggggcgctg       60

gtggaggagg aggatccttt cttcaaagtc cccgtgaaca agctggcagc ggctgtctcc      120

aacttcggct atgacctgta ccgggtgcga tccagcacga gccccacgac caacgtgctc      180

ctgtctcctc tcagtgtggc cacggccctc tcggccctct cgctgggagc ggagcagcga      240

acagaatcca tcattcaccg ggctctctac tatgacttga tcagcagccc agacatccat      300

ggtacctata aggagctcct tgacacggtc accgcccccc agaagaacct caagagtgcc      360

tcccggatcg tctttgagaa gaagctgcgc ataaaatcca gctttgtggc acctctggaa      420

aagtcatatg ggaccaggcc cagagtcctg acgggcaacc ctcgcttgga cctgcaagag      480

atcaacaact gggtgcaggc gcagatgaaa gggaagctcg ccaggtccac aaaggaaatt      540

cccgatgaga tcagcattct ccttctcggt gtggcgcact tcaaggggca gtgggtaaca      600

aagtttgact ccagaaagac ttccctcgag gatttctact tggatgaaga gaggaccgtg      660

agggtcccca tgatgtcgga ccctaaggct gttttacgct atggcttgga ttcagatctc      720

agctgcaaga ttgcccagct gcccttgacc ggaagcatga gtatcatctt cttcctgccc      780

ctgaaagtga cccagaattt gaccttgata gaggagagcc tcacctccga gttcattcat      840

gacatagacc gagaactgaa gaccgtgcag gcggtcctca ctgtccccaa gctgaagctg      900

agttacgaag gcgaagtcac caagtccctg caggagatga agctgcaatc cttgtttgat      960

tcaccagact ttagcaagat cacaggcaaa cccatcaagc tgactcaggt ggaacaccgg     1020

gctggctttg agtggaacga ggatggggcg ggaaccaccc ccagcccagg gctgcagcct     1080

gcccacctca ccttcccgct ggactatcac cttaaccagc ctttcatctt cgtactgagg     1140

gacacagaca caggggccct tctcttcatt ggcaagattc tggaccccag gggcccc        1197


<210>  5304
<211>  756
<212>  DNA
<213>  Homo Sapiens

<400>  5304
gaagcaatgt tctgtgattt tccaaaaata aaccatggaa ttctatatga tgaagaaaaa       60

tataagccat tttcccaagt tcctacaggg gaagttttct attactcctg tgaatataat      120

tttgtgtctc cttcaaaatc cttttggact cgcataacgt gcgcagaaga aggatggtca      180

ccaacaccaa agtgtctcag actgtgtttc tttccttttg tggaaaatgg tcattctgaa      240

tcttcaggac aaacacatct ggaaggtgat actgtacaaa ttatttgcaa cacaggatac      300

agacttcaaa acaatgagaa caacatttca tgtgtagaac ggggctggtc cactcctccc      360

aaatgcaggt ccactatttc tgcagaaaaa tgtgggcccc ctccacctat tgacaatgga      420

gacattactt cattcctgtt gtcagtatat gctccaggtt catcagttga gtaccagtgc      480

cagaacttgt atcaacttga gggtaacaat caaataacat gtagaaacgg acaatggtca      540

gaaccaccaa aatgcttaga tccatgtgta atatcacaag aaattatgga aaaatataac      600

ataaaattaa agtggacaaa ccaacaaaag ctttattcaa gaacaggtga catagttgaa      660

tttgtttgta aatctggata tcatccaaca aaatctcatt catttcgagc aatgtgtcag      720

aatgggaaac tggtatatcc cagttgtgaa gaaaaa                                756


<210>  5305
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  5305
gaccctgtga agccgtctcg gggcccgctg gtgacctgca cgtgtgagag cccacattgc       60

aaggggccta cctgccgggg ggcctggtgc acagtagtgc tggtgcggga ggaggggagg      120

cacccccagg aacatcgggg ctgcgggaac ttgcacaggg agctctgcag ggggcgcccc      180

accgagttcg tcaaccacta ctgctgcgac agccacctct gcaaccacaa cgtgtccctg      240

gtgctggagg ccacccaacc tccttcggag cagccgggaa cagatggcca g               291


<210>  5306
<211>  420
<212>  DNA
<213>  Homo Sapiens

<400>  5306
atggatgtat tcatgaaagg actttcaaag gccaaggagg gagttgtggc tgctgctgag       60

aaaaccaaac agggtgtggc agaagcagca ggaaagacaa aagagggtgt tctctatgta      120

ggctccaaaa ccaaggaggg agtggtgcat ggtgtggcaa cagtggctga gaagaccaaa      180

gagcaagtga caaatgttgg aggagcagtg gtgacgggtg tgacagcagt agcccagaag      240

acagtggagg gagcagggag cattgcagca gccactggct ttgtcaaaaa ggaccagttg      300

ggcaagaatg aagaaggagc cccacaggaa ggaattctgg aagatatgcc tgtggatcct      360

gacaatgagg cttatgaaat gccttctgag gaagggtatc aagactacga acctgaagcc      420


<210>  5307
<211>  1365
<212>  DNA
<213>  Homo Sapiens

<400>  5307
ctgaatttca gagcacctcc tgttattcca aatgtgcctt tcctctgggc ctggaatgcc       60

ccaagtgaat tttgtcttgg aaaatttgat gagccactag atatgagcct cttctctttc      120

ataggaagcc cccgaataaa cgccaccggg caaggtgtta caatatttta tgttgataga      180

cttggctact atccttacat agattcaatc acaggagtaa ctgtgaatgg aggaatcccc      240

cagaagattt ccttacaaga ccatctggac aaagctaaga aagacattac attttatatg      300

ccagtagaca atttgggaat ggctgttatt gactgggaag aatggagacc cacttgggca      360

agaaactgga aacctaaaga tgtttacaag aataggtcta ttgaattggt tcagcaacaa      420

aatgtacaac ttagtctcac agaggccact gagaaagcaa aacaagaatt tgaaaaagca      480

gggaaggatt tcctggtaga gactataaaa ttgggaaaat tacttcggcc aaatcacttg      540

tggggttatt atctttttcc ggattgttac aaccatcact ataagaaacc cggttacaat      600

ggaagttgct tcaatgtaga aataaaaaga aatgatgatc tcagctggtt gtggaatgaa      660

agcactgctc tttacccatc catttatttg aacactcagc agtctcctgt agctgctaca      720

ctctatgtgc gcaatcgagt tcgggaagcc atcagagttt ccaaaatacc tgatgcaaaa      780

agtccacttc cggtttttgc atatacccgc atagttttta ctgatcaagt tttgaaattc      840

ctttctcaag atgaacttgt gtatacattt ggcgaaactg ttgctctggg tgcttctgga      900

attgtaatat ggggaaccct cagtataatg cgaagtatga aatcttgctt gctcctagac      960

aattacatgg agactatact gaatccttac ataatcaacg tcacactagc agccaaaatg     1020

tgtagccaag tgctttgcca ggagcaagga gtgtgtataa ggaaaaactg gaattcaagt     1080

gactatcttc acctcaaccc agataatttt gctattcaac ttgagaaagg tggaaagttc     1140

acagtacgtg gaaaaccgac acttgaagac ctggagcaat tttctgaaaa attttattgc     1200

agctgttata gcaccttgag ttgtaaggag aaagctgatg taaaagacac tgatgctgtt     1260

gatgtgtgta ttgctgatgg tgtctgtata gatgcttttc taaaacctcc catggagaca     1320

gaagaacctc aaattttcta caatgcttca ccctccacac tatct                     1365


<210>  5308
<211>  1128
<212>  DNA
<213>  Homo Sapiens

<400>  5308
gggaaactga cagctttgga tcctgaaaca aacatgaatg tgagtgaaat tatctcttac       60

tggggattcc ctagtgagga atacctagtt gagacagaag atggatatat tctgtgcctt      120

aaccgaattc ctcatgggag gaagaaccat tctgacaaag gtcccaaacc agttgtcttc      180

ctgcaacatg gcttgctggc agattctagt aactgggtca caaaccttgc caacagcagc      240

ctgggcttca ttcttgctga tgctggtttt gacgtgtgga tgggcaacag cagaggaaat      300

acctggtctc ggaaacataa gacactctca gtttctcagg atgaattctg ggctttcagt      360

tatgatgaga tggcaaaata tgacctacca gcttccatta acttcattct gaataaaact      420

ggccaagaac aagtgtatta tgtgggtcat tctcaaggca ccactatagg ttttatagca      480

ttttcacaga tccctgagct ggctaaaagg attaaaatgt tttttgccct gggtcctgtg      540

gcttccgtcg ccttctgtac tagccctatg gccaaattag gacgattacc agatcatctc      600

attaaggact tatttggaga caaagaattt cttccccaga gtgcgttttt gaagtggctg      660

ggtacccacg tttgcactca tgtcatactg aaggagctct gtggaaatct ctgttttctt      720

ctgtgtggat ttaatgagag aaatttaaat atgtctagag tggatgtata tacaacacat      780

tctcctgctg gaacttctgt gcaaaacatg ttacactgga gccaggctgt taaattccaa      840

aagtttcaag cctttgactg gggaagcagt gccaagaatt attttcatta caaccagagt      900

tatcctccca catacaatgt gaaggacatg cttgtgccga ctgcagtctg gagcgggggt      960

cacgactggc ttgcagatgt ctacgacgtc aatatcttac tgactcagat caccaacttg     1020

gtgttccatg agagcattcc ggaatgggag catcttgact tcatttgggg cctggatgcc     1080

ccttggaggc tttataataa aattattaat ctaatgagga aatatcag                  1128


<210>  5309
<211>  1593
<212>  DNA
<213>  Homo Sapiens

<400>  5309
cagaccgccc cgcaagtact caggatcgga gggatttttg aaacagtgga aaatgagcct       60

gttaatgttg aagaattagc tttcaagttt gcagtcacca gcattaacag aaaccgaacc      120

ctgatgccta acaccacatt aacctatgac atccagagaa ttaacctttt tgatagtttt      180

gaagcctcgc ggagagcatg tgaccagctg gctcttggtg tggctgctct ctttggccct      240

tcccatagct cctccgtcag tgctgtgcag tctatttgca atgctctcga agttccacac      300

atacagaccc gctggaaaca cccctcggtg gacaacaaag atttgtttta catcaacctt      360

tacccagatt atgcagctat cagcagggcg atcctggatc tggtcctcta ttacaactgg      420

aaaacagtga cagtggtgta tgaagacagc acaggtctaa ttcgtctaca agagctcatc      480

aaagctccct ccagatataa tattaaaatc aaaatccgcc agctgccctc tgggaataaa      540

gatgccaagc ctttactcaa ggagatgaag aaaggcaagg agttctatgt gatatttgat      600

tgttcacatg aaacagccgc tgaaatcctt aagcagattc tgttcatggg catgatgacc      660

gagtactatc actacttttt cacaaccctg gacttatttg ctttggatct ggaactctat      720

aggtacagtg gcgtaaacat gaccgggttt cggctgctta acattgacaa ccctcacgtg      780

tcatccatca ttgagaagtg gtccatggag agactgcagg ccccacccag gcccgagact      840

ggccttttgg atggcatgat gacaactgaa gcggctctga tgtacgatgc tgtgtacatg      900

gtggccattg cctcgcaccg ggcatcccag ctgaccgtca gctccctgca gtgccataga      960

cataagccat ggcgcctcgg acccagattt atgaacctga tcaaagaggc ccggtgggat     1020

ggcttgactg ggcatatcac ctttaataaa accaatggct tgaggaagga ttttgatctg     1080

gacattatta gtctcaaaga ggaaggaact gaaaagattg ggatttggaa ttccaacagt     1140

gggcttaaca tgacggacag caacaaagac aagtccagca atatcactga ttcattggcc     1200

aacagaacac tcattgtcac caccattctg gaagaaccct atgttatgta caggaaatct     1260

gataagcctc tatatggaaa tgacagattt gaaggatatt gcctagacct gttgaaagaa     1320

ttgtcaaaca tcctgggttt catttatgat gttaaactag ttcccgatgg caaatatggg     1380

gcccagaatg acaaagggga gtggaacggg atggttaaag aactcataga tcacagggct     1440

gacctggcag tggctcctct taccatcacc tacgtgcggg agaaagtcat tgacttctcc     1500

aaacccttca tgaccctagg catcagcatt ctctaccgga agcccaatgg taccaatcca     1560

ggcgttttct ccttcctcaa ccccctgtct cca                                  1593


<210>  5310
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  5310
ggcttgctgg acctaaaatc aatgatcgag aaggtgacag ggaagaacgc cctgacaaac       60

tacggcttct acggctgtta ctgcggctgg ggcggccgag gaacccccaa ggatggcacc      120

gattggtgct gttgggcgca tgaccactgc tatgggcggc tggaggagaa gggctgcaac      180

attcgcacac agtcctacaa atacagattc gcgtggggcg tggtcacctg cgagcccggg      240

cccttctgcc atgtgaacct ctgtgcctgt gaccggaagc tcgtctactg cctcaagaga      300

aacctacgga gctacaaccc acagtaccaa tactttccca acatcctctg ctcc            354


<210>  5311
<211>  1095
<212>  DNA
<213>  Homo Sapiens

<400>  5311
gggcccgtat ggaggaaaca ttatatcacc tacagaatca ataattacac acctgacatg       60

aaccgtgagg atgttgacta cgcaatccgg aaagctttcc aagtatggag taatgttacc      120

cccttgaaat tcagcaagat taacacaggc atggctgaca ttttggtggt ttttgcccgt      180

ggagctcatg gagacttcca tgcttttgat ggcaaaggtg gaatcctagc ccatgctttt      240

ggacctggat ctggcattgg aggggatgca catttcgatg aggacgaatt ctggactaca      300

cattcaggag gcacaaactt gttcctcact gctgttcacg agattggcca ttccttaggt      360

cttggccatt ctagtgatcc aaaggccgta atgttcccca cctacaaata tgttgacatc      420

aacacatttc gcctctctgc tgatgacata cgtggcattc agtccctgta tggagaccca      480

aaagagaacc aacgcttgcc aaatcctgac aattcagaac cagctctctg tgaccccaat      540

ttgagttttg atgctgtcac taccgtggga aataagatct ttttcttcaa agacaggttc      600

ttctggctga aggtttctga gagaccaaag accagtgtta atttaatttc ttccttatgg      660

ccaaccttgc catctggcat tgaagctgct tatgaaattg aagccagaaa tcaagttttt      720

ctttttaaag atgacaaata ctggttaatt agcaatttaa gaccagagcc aaattatccc      780

aagagcatac attcttttgg ttttcctaac tttgtgaaaa aaattgatgc agctgttttt      840

aacccacgtt tttataggac ctacttcttt gtagataacc agtattggag gtatgatgaa      900

aggagacaga tgatggaccc tggttatccc aaactgatta ccaagaactt ccaaggaatc      960

gggcctaaaa ttgatgcagt cttctactct aaaaacaaat actactattt cttccaagga     1020

tctaaccaat ttgaatatga cttcctactc caacgtatca ccaaaacact gaaaagcaat     1080

agctggtttg gttgt                                                      1095


<210>  5312
<211>  693
<212>  DNA
<213>  Homo Sapiens

<400>  5312
attgtcaacg gggagaatgc agtgttgggc tcctggccct ggcaggtgtc cctgcaggac       60

agcagcggct tccacttctg cggtggttct ctcatcagcc agtcctgggt ggtcactgct      120

gcccactgca atgtcagccc tggccgccat tttgttgtcc tgggcgagta tgaccgatca      180

tcaaacgcag agcccttgca ggttctgtcc gtctctcggg ccattacaca ccctagctgg      240

aactctacca ccatgaacaa tgacgtgacg ctgctgaagc tcgcctcgcc agcccagtac      300

acaacacgca tctcgccagt ttgcctggca tcctcaaacg aggctctgac tgaaggcctc      360

acgtgtgtca ccaccggctg gggtcgcctc agtggcgtgg gcaatgtgac accagcacat      420

ctgcagcagg tggctttgcc cctggtcact gtgaatcagt gccggcagta ctggggctca      480

agtatcactg actccatgat ctgtgcaggt ggcgcaggtg cctcctcgtg ccagggtgac      540

tccggaggcc ctcttgtctg ccagaaggga aacacatggg tgcttattgg tattgtctcc      600

tggggcacca aaaactgcaa tgtgcgcgca cctgctgtgt atactcgagt tagcaagttc      660

agcacctgga tcaaccaggt catagcctac aac                                   693


<210>  5313
<211>  438
<212>  DNA
<213>  Homo Sapiens

<400>  5313
gtgcccatcc aaaaagtcca agatgacacc aaaaccctca tcaagacaat tgtcaccagg       60

atcaatgaca tttcacacac gcagtcagtc tcctccaaac agaaagtcac cggtttggac      120

ttcattcctg ggctccaccc catcctgacc ttatccaaga tggaccagac actggcagtc      180

taccaacaga tcctcaccag tatgccttcc agaaacgtga tccaaatatc caacgacctg      240

gagaacctcc gggatcttct tcacgtgctg gccttctcta agagctgcca cttgccctgg      300

gccagtggcc tggagacctt ggacagcctg gggggtgtcc tggaagcttc aggctactcc      360

acagaggtgg tggccctgag caggctgcag gggtctctgc aggacatgct gtggcagctg      420

gacctcagcc ctgggtgc                                                    438


<210>  5314
<211>  957
<212>  DNA
<213>  Homo Sapiens

<400>  5314
attataggag cacagcctct ctgcagccaa ctggcaggac tttctcaagg acagaagaaa       60

ctgtgccact tgtatcagga ccacatgcag tacatcggag aaggcgcgaa gacaggcatc      120

aaagaatgcc agtatcaatt ccgacatcga aggtggaact gcagcactgt ggataacacc      180

tctgtttttg gcagggtgat gcagataggc agccgcgaga cggccttcac atacgcggtg      240

agcgcagcag gggtggtgaa cgccatgagc cgggcgtgcc gcgagggcga gctgtccacc      300

tgcggctgca gccgcgccgc gcgccccaag gacctgccgc gggactggct ctggggcggc      360

tgcggcgaca acatcgacta tggctaccgc tttgccaagg agttcgtgga cgcccgcgag      420

cgggagcgca tccacgccaa gggctcctac gagagtgctc gcatcctcat gaacctgcac      480

aacaacgagg ccggccgcag gacggtgtac aacctggctg atgtggcctg caagtgccat      540

ggggtgtccg gctcatgtag cctgaagaca tgctggctgc agctggcaga cttccgcaag      600

gtgggtgatg ccctgaagga gaagtacgac agcgcggcgg ccatgcggct caacagccgg      660

ggcaagttgg tacaggtcaa cagccgcttc aactcgccca ccacacaaga cctggtctac      720

atcgacccca gccctgacta ctgcgtgcgc aatgagagca ccggctcgct gggcacgcag      780

ggccgcctgt gcaacaagac gtcggagggc atggatggct gcgagctcat gtgctgcggc      840

cgtggctacg accagttcaa gaccgtgcag acggagcgct gccactgcaa gttccactgg      900

tgctgctacg tcaagtgcaa gaagtgcacg gagatcgtgg accagtttgt gtgcaag         957


<210>  5315
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  5315
gcaccggagg cccaggtctc cgtgcagccc aacttccagc aggacaagtt cctggggcgc       60

tggttcagcg cgggcctcgc ctccaactcg agctggctcc gggagaagaa ggcggcgttg      120

tccatgtgca agtctgtggt ggcccctgcc acggatggtg gcctcaacct gacctccacc      180

ttcctcagga aaaaccagtg tgagacccga accatgctgc tgcagcccgc ggggtccctc      240

ggctcctaca gctaccggag tccccactgg ggcagcacct actccgtgtc agtggtggag      300

accgactacg accagtacgc gctgctgtac agccagggca gcaagggccc tggcgaggac      360

ttccgcatgg ccaccctcta cagccgaacc cagaccccca gggctgagtt aaaggagaaa      420

ttcaccgcct tctgcaaggc ccagggcttc acagaggata ccattgtctt cctgccccaa      480

accgataagt gcatgacgga acaa                                             504


<210>  5316
<211>  660
<212>  DNA
<213>  Homo Sapiens

<400>  5316
agtgcgcggg ccaggacgga cctgctcaat gtctgcatga acgccaagca ccacaagaca       60

cagcccagcc ccgaggacga gctgtatggc cagtgcagtc cctggaagaa gaatgcctgc      120

tgcacggcca gcaccagcca ggagctgcac aaggacacct cccgcctgta caactttaac      180

tgggatcact gtggtaagat ggaacccacc tgcaagcgcc actttatcca ggacagctgt      240

ctctatgagt gctcacccaa cctggggccc tggatccggc aggtcaacca gagctggcgc      300

aaagagcgca ttctgaacgt gcccctgtgc aaagaggact gtgagcgctg gtgggaggac      360

tgtcgcacct cctacacctg caaaagcaac tggcacaaag gctggaattg gacctcaggg      420

attaatgagt gtccggccgg ggccctctgc agcacctttg agtcctactt ccccactcca      480

gccgcccttt gtgaaggcct ctggagccac tccttcaagg tcagcaacta tagtcgaggg      540

agcggccgct gcatccagat gtggtttgac tcagcccagg gcaaccccaa tgaggaggtg      600

gccaagttct atgctgcggc catgaatgct ggggccccgt ctcgtgggat tattgattcc      660


<210>  5317
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  5317
cacctgccac ctgaggagaa gctccgagat gacaggagcc tgagaagcaa ctcctctgtg       60

aacctactgg atgtcccttc tgtctctatt gtggcgctga acaagaaatc caaacagatc      120

ggcagaaaag cagcagaaaa gaaaagatct tctaagaagg aggcttcgat gaagaaagtg      180

gtgcggcccc ggacccccct atctgcgccc tgcgtggcca cccgcaacag ctgcaagccg      240

ccggcacccg cctgctgcga cccgtgcgcc tcctgccagt gccgcttctt ccgcagcgcc      300

tgctcctgcc gcgtgctcag cctcaactgc                                       330


<210>  5318
<211>  1554
<212>  DNA
<213>  Homo Sapiens

<400>  5318
gccaatttcc ccaacaatat ccagatcggg ggattatttc caaaccagca gtcacaggaa       60

catgctgctt ttagatttgc tttgtcgcaa ctcacagagc ccccgaagct gctcccccag      120

attgatattg tgaacatcag cgacagcttt gagatgacct atagattctg ttcccagttc      180

tccaaaggag tctatgccat ctttgggttt tatgaacgta ggactgtcaa catgctgacc      240

tccttttgtg gggccctcca cgtctgcttc attacgccga gctttcccgt tgatacatcc      300

aatcagtttg tccttcagct gcgccctgaa ctgcaggatg ccctcatcag catcattgac      360

cattacaagt ggcagaaatt tgtctacatt tatgatgccg accggggctt atccgtcctg      420

cagaaagtcc tggatacagc tgctgagaag aactggcagg tgacagcagt caacatcttg      480

acaaccacag aggagggata ccggatgctc tttcaggacc tggagaagaa aaaggagcgg      540

ctggtggtgg tggactgtga atcagaacgc ctcaatgcta tcttgggcca gattataaag      600

ctagagaaga atggcatcgg ctaccactac attcttgcaa atctgggctt catggacatt      660

gacttaaaca aattcaagga gagtggcgcc aatgtgacag gtttccagct ggtgaactac      720

acagacacta ttccggccaa gatcatgcag cagtggaaga atagtgatgc tcgagaccac      780

acacgggtgg actggaagag acccaagtac acctctgcgc tcacctacga tggggtgaag      840

gtgatggctg aggctttcca gagcctgcgg aggcagagaa ttgatatatc tcgccggggg      900

aatgctgggg attgtctggc taacccagct gttccctggg gccaagggat cgacatccag      960

agagctctgc agcaggtgcg atttgaaggt ttaacaggaa acgtgcagtt taatgagaaa     1020

ggacgccgga ccaactacac gctccacgtg attgaaatga aacatgacgg catccgaaag     1080

attggttact ggaatgaaga tgataagttt gtccctgcag ccaccgatgc ccaagctggg     1140

ggcgataatt caagtgttca gaacagaaca tacatcgtca caacaatcct agaagatcct     1200

tatgtgatgc tcaagaagaa cgccaatcag tttgagggca atgaccgtta cgagggctac     1260

tgtgtagagc tggcggcaga gattgccaag cacgtgggct actcctaccg tctggagatt     1320

gtcagtgatg gaaaatacgg agcccgagac cctgacacga aggcctggaa tggcatggtg     1380

ggagagctgg tctatggaag agcagatgtg gctgtggctc ccttaactat cactttggtc     1440

cgggaagaag ttatagattt ctccaaacca tttatgagtt tggggatctc catcatgatt     1500

aaaaaaccac agaaatccaa gccgggtgtc ttctccttcc ttgatccttt ggct           1554


<210>  5319
<211>  1572
<212>  DNA
<213>  Homo Sapiens

<400>  5319
ggattcccca acaccatcag cataggtgga cttttcatga gaaacacagt gcaggagcac       60

agcgctttcc gctttgccgt gcagttatac aacaccaacc agaacaccac cgagaagccc      120

ttccatttga attaccacgt agatcacttg gattcctcca atagtttttc cgtgacaaat      180

gctttctgct cccagttctc gagaggggtg tatgccatct ttggattcta tgaccagatg      240

tcaatgaaca ccctgacctc cttctgtggg gccctgcaca catcctttgt tacgcctagc      300

ttccccactg acgcagatgt gcagtttgtc atccagatgc gcccagcctt gaagggcgct      360

attctgagtc ttctgggtca ttacaagtgg gagaagtttg tgtacctcta tgacacagaa      420

cgaggatttt ccatcctcca agcgattatg gaagcagcag tgcaaaacaa ctggcaagta      480

acagcaaggt ctgtgggaaa cataaaggac gtccaagaat tcaggcgcat cattgaagaa      540

atggacagga ggcaggaaaa gcgatacttg attgactgcg aagtcgaaag gattaacaca      600

attttggaac aggttgtgat cctagggaaa cactcaagag gttatcacta catgctcgct      660

aacctgggtt ttactgatat tttactggaa agagtcatgc atgggggagc caacattaca      720

ggtttccaga ttgtcaacaa tgaaaaccct atggttcagc agttcataca gcgctgggtg      780

aggctggatg aaagggaatt ccctgaagcc aagaatgcac cactaaagta tacatctgca      840

ttgacacacg acgcaatact ggtcatagca gaagctttcc gctacctgag gaggcagcga      900

gtagatgtgt cccggagagg aagtgctgga gactgcttag caaatcctgc tgtgccctgg      960

agtcaaggaa ttgatattga gagagctctg aaaatggtgc aagtacaagg aatgactgga     1020

aatattcaat ttgacactta tggacgtagg acaaattata ccatcgatgt gtatgaaatg     1080

aaagtcagtg gctctcgaaa agctggctac tggaacgagt atgaaaggtt tgtgcctttc     1140

tcagatcagc aaatcagcaa tgacagtgca tcctcagaga atcggaccat agtagtgact     1200

accattctgg aatcaccata tgtaatgtac aagaagaacc atgagcaact ggaaggaaat     1260

gaacgatatg aaggctattg tgtagaccta gcctatgaaa tagccaaaca tgtaaggatc     1320

aaatacaaat tgtccatcgt tggtgacggg aaatatggtg caagggatcc agagactaaa     1380

atatggaacg gcatggttgg ggaacttgtc tatgggagag ctgatatagc tgttgctcca     1440

ctcactataa cattggtccg tgaagaagtc atagattttt caaagccatt catgagcctg     1500

ggcatctcca tcatgataaa gaagcctcag aaatcaaaac caggcgtatt ctcatttctg     1560

gatcccctgg ct                                                         1572


<210>  5320
<211>  2247
<212>  DNA
<213>  Homo Sapiens

<400>  5320
ctgacaccag cggaagataa tagtctgtct caaaagaaga aggtcactgt agaagatctc       60

ttcagtgaag acttcaaaat tcatgacccc gaggctaagt ggataagtga tacagaattc      120

atctacagag aacagaaagg aacagtgaga ctgtggaatg ttgaaacaaa tacttctact      180

gtcttaatag aaggcaaaaa aattgaatca ttaagagcca tcagatatga aatatctcca      240

gatagagagt atgcactttt ttcatacaat gtggaaccca tatatcaaca ctcgtatact      300

ggatattatg tcctgagcaa aattcctcat ggggatcctc aaagtctgga cccaccagaa      360

gtcagcaatg caaagcttca gtatgcagga tggggcccta aaggccaaca gctgatattt      420

atttttgaaa acaatatcta ctactgtgca catgtcggga aacaggccat ccgtgtggtc      480

tccactggca aggaaggtgt gatttacaat ggcctcagtg actggctgta tgaagaggag      540

attttgaaga cacacatcgc acactggtgg tctccggatg gcacgagact cgcctacgcc      600

gccatcaatg attcccgtgt ccccatcatg gagctcccaa cttacaccgg ctccatctac      660

cccaccgtga agccctacca ctatcccaag gctggaagtg agaaccccag catttcccta      720

cacgttattg gcttaaatgg acccacccat gatctggaga tgatgccgcc tgatgatcca      780

cggatgaggg agtactacat caccatggtg aagtgggcca ccagcaccaa ggtcgccgtg      840

acctggctga accgggcgca gaacgtgtcc atcctcaccc tctgcgacgc caccacgggg      900

gtctgcacga agaaacacga ggatgaaagt gaggcctggc tccacagaca gaatgaagaa      960

cctgtgttct ccaaggatgg ccgaaagttt ttcttcatca gagccatccc ccagggagga     1020

cgagggaaat tctatcacat cacggtgtcc tcgtcccagc ccaacagcag caacgacaac     1080

atccagtcca tcacctccgg ggactgggac gtgaccaaga tcctagccta cgatgagaag     1140

gggaataaga tctacttcct gagcacggag gacctgcctc ggagacgaca actctacagt     1200

gccaacacgg tgggcaactt caacaggcag tgcctctcct gtgacctggt tgagaactgc     1260

acctacttca gcgcttcctt cagccatagc atggacttct tcctgctcaa gtgcgaaggt     1320

cctggtgttc ctatggtgac ggtgcacaac acaacagata agaaaaaaat gtttgaccta     1380

gaaacaaatg aacatgtcaa gaaggccata aatgaccgac agatgcctaa agtggaatac     1440

agggacattg agattgatga ttacaacctg cccatgcaga tactgaagcc agcaaccttc     1500

accgacacca cccactaccc tctgctcctg gtggtggatg gcaccccggg cagccagagt     1560

gtagctgaga agttcgaggt gagctgggag acggtgatgg tgagcagcca cggcgcggtg     1620

gtggtaaagt gtgaaggccg tggcagcggc ttccgaggga ccaagctcct gcacgaagtg     1680

aggcggcggc tgggcttgct ggaggagaag gaccagatgg aggccgtgcg gacgatgctg     1740

aaggagcagt acattgacag gacgcgcgtg gccgtgtttg ggaaggatta cggtggctac     1800

ctgagcacct acatcctccc agcaaaggga gaaaatcaag gccagacatt cacctgcggc     1860

tctgctctct ctccaataac agacttcaaa ctctatgcct ctgcgttttc cgagaggtac     1920

ttgggcctcc atggacttga caacagagca tacgagatga ccaaggtagc ccatcgagtc     1980

tccgcgctgg aagaacagca gttcctgatc attcatccca ctgccgatga aaaaattcat     2040

ttccagcaca cagcagaact cattacacaa ctaattaggg gaaaggctaa ttacagctta     2100

cagatttacc cggacgaaag ccattacttt accagctcca gcctcaaaca gcatctgtac     2160

cggtccatca tcaacttctt cgtggaatgc ttcaggatcc aggacaaact gctgacagtc     2220

acagcgaaag aggacgagga ggaggac                                         2247


<210>  5321
<211>  1353
<212>  DNA
<213>  Homo Sapiens

<400>  5321
aagaactatt cggttctcta cttccaacag aaggttgatc attttggatt taatactgtg       60

aaaactttta atcagcggta cctagtagct gataaatact ggaagaaaaa tggtggatca      120

atacttttct acactggtaa tgaaggggac attatctggt tttgtaataa cacggggttc      180

atgtgggatg tggctgagga actgaaagct atgttggtgt ttgctgaaca tcgatactat      240

ggagagtctc tcccctttgg tgacaactca ttcaaggatt ccagacactt gaatttcctg      300

acatcagaac aagctctggc tgattttgca gagttaatca aacacttgaa aagaacaatc      360

ccaggagctg aaaatcaacc tgtcattgcc ataggaggct cctatggtgg catgcttgcc      420

gcctggttta ggatgaaata tcctcatatg gtagttggag ctcttgcagc ttctgcccct      480

atctggcagt ttgaggattt agtaccttgt ggtgtattta tgaagatcgt aactacagat      540

tttaggaaaa gcggtccaca ttgttcagag agcatccaca ggtcctggga tgccattaat      600

cgactctcaa atactggcag tggtttgcag tggcttactg gagcccttca cttatgcagc      660

ccattaactt ctcaggacat ccaacatttg aaagactgga tctctgaaac ctgggtgaat      720

ctggcaatgg tggactatcc ttatgcctct aactttttac agcctttgcc tgcttggcct      780

atcaaggtag tgtgccagta tttgaaaaat cccaatgtat ctgattcact gctgctgcag      840

aatattttcc aagctctgaa tgtatattac aattattcgg gccaggtgaa atgcctgaat      900

atttcagaga cagcaactag cagtctggga acactgggtt ggagctatca ggcctgcaca      960

gaagtagtca tgcccttttg tactaatggt gtcgatgaca tgtttgaacc tcactcatgg     1020

aacttaaagg aactttctga tgactgtttt caacagtggg gtgtgagacc aaggccctcc     1080

tggatcacta ctatgtatgg aggcaaaaac attagttcac acacaaacat tgttttcagc     1140

aatggtgaac tagacccctg gtcaggaggt ggagtaacta aggatatcac agacactctg     1200

gttgcagtca ccatctcaga gggggcccac cacttagatc tccgcaccaa gaatgccttg     1260

gatcctatgt ctgtgctgtt agcccgctcc ttggaagtta gacatatgaa gaattggatc     1320

agagatttct atgacagtgc gggaaagcag cac                                  1353


<210>  5322
<211>  2043
<212>  DNA
<213>  Homo Sapiens

<400>  5322
cagtaccaga caagatcccc ctctgtgtgc ctgagcgaag cttgtgtctc agtgaccagc       60

tccatcttga gctccatgga ccccacagtg gacccctgcc atgacttctt cagctacgcc      120

tgtgggggct ggatcaaggc caacccagtc cctgatggcc actcacgctg ggggaccttc      180

agcaacctct gggaacacaa ccaagcaatc atcaagcacc tcctcgaaaa ctccacggcc      240

agcgtgagcg aggcagagag aaaggcgcaa gtatactacc gtgcgtgcat gaacgagacc      300

aggatcgagg agctcagggc caaacctcta atggagttga ttgagaggct cgggggctgg      360

aacatcacag gtccctgggc caaggacaac ttccaggaca ccctgcaggt ggtcaccgcc      420

cactaccgca cctcaccctt cttctctgtc tatgtcagtg ccgattccaa gaactccaac      480

agcaacgtga tccaggtgga ccagtctggc ctgggcttgc cctcgagaga ctattacctg      540

aacaaaactg aaaacgagaa ggtgctgacc ggatatctga actacatggt ccagctgggg      600

aagctgctgg gcggcgggga cgaggaggcc atccggcccc agatgcagca gatcttggac      660

tttgagacgg cactggccaa catcaccatc ccacaggaga agcgccgtga tgaggagctc      720

atctaccaca aagtgacggc agccgagctg cagaccttgg cacccgccat caactggttg      780

ccttttctca acaccatctt ctaccccgtg gagatcaatg aatccgagcc tattgtggtc      840

tatgacaagg aataccttga gcagatctcc actctcatca acaccaccga cagatgcctg      900

ctcaacaact acatgatctg gaacctggtg cggaaaacaa gctccttcct tgaccagcgc      960

tttcaggacg ccgatgagaa gttcatggaa gtcatgtacg ggaccaagaa gacctgtctt     1020

cctcgctgga agttttgcgt gagtgacaca gaaaacaacc tgggctttgc gttgggcccc     1080

atgtttgtca aagcaacctt cgccgaggac agcaagagca tagccaccga gatcatcctg     1140

gagattaaga aggcatttga ggaaagcctg agcaccctga agtggatgga tgaggaaacc     1200

cgaaaatcag ccaaggaaaa ggccgatgcc atctacaaca tgataggata ccccaacttc     1260

atcatggatc ccaaggagct ggacaaagtg tttaatgact acactgcagt tccagacctc     1320

tactttgaaa atgccatgcg gtttttcaac ttctcatgga gggtcactgc cgatcagctc     1380

aggaaagccc ccaacagaga tcagtggagc atgaccccgc ccatggtgaa cgcctactac     1440

tcgcccacca agaatgagat tgtgtttccg gccgggatcc tgcaggcacc attctacaca     1500

cgctcctcac ccaaggcctt aaactttggt ggcataggtg tcgtcgtggg ccatgagctg     1560

actcatgctt ttgatgatca aggacgggag tatgacaagg acgggaacct ccggccatgg     1620

tggaagaact catccgtgga ggccttcaag cgtcagaccg agtgcatggt agagcagtac     1680

agcaactaca gcgtgaacgg ggagccggtg aacgggcggc acaccctggg ggagaacatc     1740

gccgacaacg ggggtctcaa ggcggcctat cgggcttacc agaactgggt gaagaagaac     1800

ggggctgagc actcgctccc caccctgggc ctcaccaata accagctctt cttcctgggc     1860

tttgcacagg tctggtgctc cgtccgcaca cctgagagct cccacgaagg cctcatcacc     1920

gatccccaca gcccctctcg cttccgggtc atcggctccc tctccaattc caaggagttc     1980

tcagaacact tccgctgccc acctggctca cccatgaacc cgcctcacaa gtgcgaagtc     2040

tgg                                                                   2043


<210>  5323
<211>  273
<212>  DNA
<213>  Homo Sapiens

<400>  5323
agcatcaagc ctggtgtcac ccagaaagtg ggtgaaattg cgaggacagg cagcacccct       60

gaagtcagta cggtggatgc catgttagat ctcatcagga atatgttccc tgagaatctt      120

gtccaggcct gttttcagca gtacaaaact aagcgtgaag aagtgaagcc tcccagcgat      180

ccagagatga acatgacaga agagtccttc acagctgtca tgacaactgc aatttccaag      240

aacaaaacaa aggaatacaa aattgttggc atg                                   273


<210>  5324
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5324
aagccaggat ccggtgcgca gacccttcag tccagcgacc tggggctgga ggactcgggg       60

cctcctcctg tccccaaaga gacggtggac tctttcctcg acctggccag aaacctgttt      120

ccctccaatc ttgtggttgc agctttccgt acgtatgcaa ccgattataa agtcgtgacc      180

cagaacagca gctctggaaa tgtaacccat gaaaagatcc ccataggcac t               231


<210>  5325
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  5325
ttgccgttaa gatttgactg gagggacaag caggttgtga cacaagtgag aaaccagcag       60

atgtgtggag gatgctgggc cttcagcgtg gtgggggcag tggaatctgc ttatgcaata      120

aaggggaagc ccctggaaga cctaagtgtc cagcaggtca ttgactgttc gtataataat      180

tatggctgca atggaggctc tactctcaat gctttgaact ggttaaacaa gatgcaagta      240

aaactggtga aagattcaga atatcctttt aaagcacaaa atggtctgtg ccattacttt      300

tctggttcac attctggatt ttcaatcaaa ggttattctg catatgactt cagtgaccaa      360

gaagatgaaa tggcaaaagc acttcttacc tttggccctt tggtagtcat agtagatgca      420

gtgagctggc aagattatct gggaggcatt atacagcatc actgctctag tggagaagca      480

aatcatgcag ttctcataac tgggtttgat aaaacaggaa gcactccata ttggattgtg      540

cggaattcct ggggaagttc ttggggagta gatggttatg cccatgtcaa aatgggaagt      600

aatgtttgtg gtattgcaga ttccgtttct tctatatttg tg                         642


<210>  5326
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  5326
gccccagact ctgtcgacta tcgaaagaaa ggatatgtta ctcctgtcaa aaatcagggt       60

cagtgtggtt cctgttgggc ttttagctct gtgggtgccc tggagggcca actcaagaag      120

aaaactggca aactcttaaa tctgagtccc cagaacctag tggattgtgt gtctgagaat      180

gatggctgtg gagggggcta catgaccaat gccttccaat atgtgcagaa gaaccggggt      240

attgactctg aagatgccta cccatatgtg ggacaggaag agagttgtat gtacaaccca      300

acaggcaagg cagctaaatg cagagggtac agagagatcc ccgaggggaa tgagaaagcc      360

ctgaagaggg cagtggcccg agtgggacct gtctctgtgg ccattgatgc aagcctgacc      420

tccttccagt tttacagcaa aggtgtgtat tatgatgaaa gctgcaatag cgataatctg      480

aaccatgcgg ttttggcagt gggatatgga atccagaagg gaaacaagca ctggataatt      540

aaaaacagct ggggagaaaa ctggggaaac aaaggatata tcctcatggc tcgaaataag      600

aacaacgcct gtggcattgc caacctggcc agcttcccca agatg                      645


<210>  5327
<211>  1506
<212>  DNA
<213>  Homo Sapiens

<400>  5327
gcccacaccg gggaggagag cgtggctgac catcacgagg ctgaatatta tgtggctgcc       60

gtgtatgagc atccatccat cctgagtctg aaccctctgg ctctcatcag ccgccaagag      120

gccttggagc tcatgaacca gaaccttgac atctatgaac agcaagtgat gactgcagcc      180

caaaaggatg tacagattat agtgtttcca gaagatggca ttcatggatt caactttaca      240

agaacatcca tttatccatt tttggacttc atgccgtctc cccaggtggt caggtggaac      300

ccatgcctgg agcctcaccg cttcaatgac acagaggtgc tccagcgcct gagttgtatg      360

gccatcaggg gagatatgtt cttggtggcc aatcttggga caaaggagcc ttgtcatagc      420

agtgacccaa ggtgcccaaa agatgggaga taccagttca acacaaatgt cgtgttcagc      480

aataatggaa cccttgttga ccgctaccgt aaacacaacc tctactttga ggcagcattc      540

gatgttcctc ttaaagtgga tctcatcacc tttgataccc cctttgctgg caggtttggc      600

atcttcacat gctttgatat attgttcttt gaccctgcca tcagagtcct cagagactac      660

aaggtgaagc atgttgtgta cccaactgcc tggatgaacc agctcccact cttggcagca      720

attgagattc agaaagcttt tgctgttgcc tttggcatca acgttctggc agctaatgtc      780

caccacccag ttctggggat gacaggaagt ggcatacaca cccctctgga gtccttttgg      840

taccatgaca tggaaaatcc caaaagtcac cttataattg cccaggtggc caaaaatcca      900

gtgggtctca ttggtgcaga gaatgcaaca ggtgaaacgg acccatccca tagtaagttt      960

ttaaaaattt tgtcaggcga tccgtactgt gagaaggatg ctcaggaagt ccactgtgat     1020

gaggccacca agtggaacgt gaatgctcct cccacatttc actctgagat gatgtatgac     1080

aatttcaccc tggtccctgt ctggggaaag gaaggctatc tccacgtctg ttccaatggc     1140

ctctgctgtt atttacttta cgagaggccc accttatcca aagagctgta tgccctgggg     1200

gtctttgatg ggcttcacac agtacatggc acttactaca tccaagtgtg tgccctggtc     1260

aggtgtgggg gtcttggctt cgacacctgt ggacaggaaa tcacagaggc cacggggata     1320

tttgagtttc acctgtgggg caacttcagt acttcctata tctttccttt gtttctgacc     1380

tcagggatga ccctagaagt ccctgaccag cttggctggg agaatgacca ctatttcctg     1440

aggaaaagta ggctgtcctc tgggctggtg acggcggctc tctatgggcg cttgtatgag     1500

agggac                                                                1506


<210>  5328
<211>  1473
<212>  DNA
<213>  Homo Sapiens

<400>  5328
atgaatcctg cggcagaagc cgagttcaac atcctcctgg ccaccgactc ctacaaggtt       60

actcactata aacaatatcc acccaacaca agcaaagttt attcctactt tgaatgccgt      120

gaaaagaaga cagaaaactc caaattaagg aaggtgaaat atgaggaaac agtattttat      180

gggttgcagt acattcttaa taagtactta aaaggtaaag tagtaaccaa agagaaaatc      240

caggaagcca aagatgtcta caaagaacat ttccaagatg atgtctttaa tgaaaaggga      300

tggaactaca ttcttgagaa gtatgatggg catcttccaa tagaaataaa agctgttcct      360

gagggctttg tcattcccag aggaaatgtt ctcttcacgg tggaaaacac agatccagag      420

tgttactggc ttacaaattg gattgagact attcttgttc agtcctggta tccaatcaca      480

gtggccacaa attctagaga gcagaagaaa atattggcca aatatttgtt agaaacttct      540

ggtaacttag atggtctgga atacaagtta catgattttg gctacagagg agtctcttcc      600

caagagactg ctggcatagg agcatctgct cacttggtta acttcaaagg aacagataca      660

gtagcaggac ttgctctaat taaaaaatat tatggaacga aagatcctgt tccaggctat      720

tctgttccag cagcagaaca cagtaccata acagcttggg ggaaagacca tgaaaaagat      780

gcttttgaac atattgtaac acagttttca tcagtgcctg tatctgtggt cagcgatagc      840

tatgacattt ataatgcgtg tgagaaaata tggggtgaag atctaagaca tttaatagta      900

tcgagaagta cacaggcacc actaataatc agacctgatt ctggaaaccc tcttgacact      960

gtgttaaagg ttttggagat tttaggtaag aagtttcctg ttactgagaa ctcaaagggt     1020

tacaagttgc tgccacctta tcttagagtt attcaagggg atggagtaga tattaatacc     1080

ttacaagaga ttgtagaagg catgaaacaa aaaatgtgga gtattgaaaa tattgccttc     1140

ggttctggtg gaggtttgct acagaagttg acaagagatc tcttgaattg ttccttcaag     1200

tgtagctatg ttgtaactaa tggccttggg attaacgtct tcaaggaccc agttgctgat     1260

cccaacaaaa ggtccaaaaa gggccgatta tctttacata ggacgccagc agggaatttt     1320

gttacactgg aggaaggaaa aggagacctt gaggaatatg gtcaggatct tctccatact     1380

gtcttcaaga atggcaaggt gacaaaaagc tattcatttg atgaaataag aaaaaatgca     1440

cagctgaata ttgaactgga agcagcacat cat                                  1473


<210>  5329
<211>  1734
<212>  DNA
<213>  Homo Sapiens

<400>  5329
ctgcccacac aacctcggga tatagagaac ttcaatagta ctcaaaaatt tatagaagat       60

aatattgaat acatcaccat cattgcattt gctcagtatg ttcaggaagc aacctttgaa      120

gaaatggaaa agctggtgaa agacatggta gaatacaaag acagatgtat ggctgacaag      180

acgctcccag agtgttcaaa attacctaat aatgttttac aggaaaaaat atgtgctatg      240

gaggggctgc cacaaaagca taatttctca cactgctgca gtaaggttga tgctcaaaga      300

agactctgtt tcttctataa caagaaatct gatgtgggat ttctgcctcc tttccctacc      360

ctggatcccg aagagaaatg ccaggcttat gaaagtaaca gagaatccct tttaaatcac      420

tttttatatg aagttgccag aaggaaccca tttgtcttcg cccctacact tctaactgtt      480

gctgttcatt ttgaggaggt ggccaaatca tgttgtgaag aacaaaacaa agtcaactgc      540

cttcaaacaa gggcaatacc tgtcacacaa tatttaaaag cattttcttc ttatcaaaaa      600

catgtctgtg gggcactttt gaaatttgga accaaagttg tacactttat atatattgcg      660

atactcagtc aaaaattccc caagattgaa tttaaggagc ttatttctct tgtagaagat      720

gtttcttcca actatgatgg atgctgtgaa ggggatgttg tgcagtgcat ccgtgacacg      780

agcaaggtta tgaaccatat ttgttcaaaa caagattcta tctccagcaa aatcaaagag      840

tgctgtgaaa agaaaatacc agagcgcggc cagtgcataa ttaactcaaa caaagatgat      900

agaccaaagg atttatctct aagagaagga aaatttactg acagtgaaaa tgtgtgtcaa      960

gaacgagatg ctgacccaga caccttcttt gcgaagttta cttttgaata ctcaaggaga     1020

catccagacc tgtctatacc agagctttta agaattgttc aaatatacaa agatctcctg     1080

agaaattgct gcaacacaga aaaccctcca ggttgttacc gttacgcgga agacaaattc     1140

aatgagacaa ctgagaaaag cctcaagatg gtacaacaag aatgtaaaca tttccagaat     1200

ttggggaagg atggtttgaa ataccattac ctcatcaggc tcacgaagat agctccccaa     1260

ctctccactg aagaactggt gtctcttggc gagaaaatgg tgacagcttt cactacttgc     1320

tgtacgctaa gtgaagagtt tgcctgtgtt gataatttgg cagatttagt ttttggagag     1380

ttatgtggag taaatgaaaa tcgaactatc aaccctgctg tggaccactg ctgtaaaaca     1440

aactttgcct tcagaaggcc ctgctttgag agtttgaaag ctgataaaac atatgtgcct     1500

ccacctttct ctcaagattt atttaccttt cacgcagaca tgtgtcaatc tcagaatgag     1560

gagcttcaga ggaagacaga caggtttctt gtcaacttag tgaagctgaa gcatgaactc     1620

acagatgaag agctgcagtc tttgtttaca aatttcgcaa atgtagtgga taagtgctgc     1680

aaagcagaga gtcctgaagt ctgctttaat gaagagagtc caaaaattgg caac           1734


<210>  5330
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  5330
catgtggaga cccgggccca cgccgaggag cggctcctga agaaactctt ctccggttac       60

aacaagtggt cccgacccgt ggccaacatc tcggacgtgg tcctcgtccg cttcggcctg      120

tccatcgctc agctcattga cgtggatgag aagaaccaga tgatgaccac gaacgtatgg      180

gtgaagcagg agtggcacga ctacaagctg cgctgggacc cagctgacta tgagaatgtc      240

acctccatcc gcatcccctc cgagctcatc tggcggccgg acatcgtcct ctacaacaat      300

gctgacgggg acttcgcggt cacccacctg accaaggccc acctgttcca tgacgggcgg      360

gtgcagtgga ctcccccggc catttacaag agctcctgca gcatcgacgt caccttcttc      420

cccttcgacc agcagaactg caccatgaaa ttcggctcct ggacctacga caaggccaag      480

atcgacctgg tgaacatgca cagccgcgtg gaccagctgg acttctggga gagtggcgag      540

tgggtcatcg tggacgccgt gggcacctac aacaccagga agtacgagtg ctgcgccgag      600

atctacccgg acatcaccta tgccttcgtc atccggcggc tg                         642


<210>  5331
<211>  1104
<212>  DNA
<213>  Homo Sapiens

<400>  5331
tacaatgttt tccctcgaac tcttaaatgg tccaaaatga atttaaccta cagaattgtg       60

aattacaccc ctgatatgac tcattctgaa gtcgaaaagg cattcaaaaa agccttcaaa      120

gtttggtccg atgtaactcc tctgaatttt accagacttc acgatggcat tgctgacatc      180

atgatctctt ttggaattaa ggagcatggc gacttctacc catttgatgg gccctctggc      240

ctgctggctc atgcttttcc tcctgggcca aattatggag gagatgccca ttttgatgat      300

gatgaaacct ggacaagtag ttccaaaggc tacaacttgt ttcttgttgc tgcgcatgag      360

ttcggccact ccttaggtct tgaccactcc aaggaccctg gagcactcat gtttcctatc      420

tacacctaca ccggcaaaag ccactttatg cttcctgatg acgatgtaca agggatccag      480

tctctctatg gtccaggaga tgaagacccc aaccctaaac atccaaaaac gccagacaaa      540

tgtgaccctt ccttatccct tgatgccatt accagtctcc gaggagaaac aatgatcttt      600

aaagacagat tcttctggcg cctgcatcct cagcaggttg atgcggagct gtttttaacg      660

aaatcatttt ggccagaact tcccaaccgt attgatgctg catatgagca cccttctcat      720

gacctcatct tcatcttcag aggtagaaaa ttttgggctc ttaatggtta tgacattctg      780

gaaggttatc ccaaaaaaat atctgaactg ggtcttccaa aagaagttaa gaagataagt      840

gcagctgttc actttgagga tacaggcaag actctcctgt tctcaggaaa ccaggtctgg      900

agatatgatg atactaacca tattatggat aaagactatc cgagactaat agaagaagac      960

ttcccaggaa ttggtgataa agtagatgct gtctatgaga aaaatggtta tatctatttt     1020

ttcaacggac ccatacagtt tgaatacagc atctggagta accgtattgt tcgcgtcatg     1080

ccagcaaatt ccattttgtg gtgt                                            1104


<210>  5332
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  5332
gacaccatcc ccacgtacct acagtggatg tcctacatct cctatgtcag gtatgggttc       60

gaaggggtca tcctctccat ctatggctta gaccgggaag atctgcactg tgacatcgac      120

gagacgtgcc acttccagaa gtcggaggcc atcctgcggg agctggacgt ggaaaatgcc      180

aagctgtac                                                              189


<210>  5333
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  5333
gataaaactc ttccagtctt ccccaaagga aacgaagtcc aaattaaagt tttgaatata       60

ggaaacaata ccatgaatat atctcttcct ggagagatgg tgacacttgg cccaatgtct      120

caaacaaatg catttatgac ttttgatgta aacaaactga caaggataaa catttcttct      180

cctggatcac cagtcactgc cgtaactgac gacttcaagc agggccaacg ccacacgctt      240

ctagtgtggg cccccaatca ctaccaggtg gtaaaggatg gtcttaacca gaagccagaa      300

aaaggggaaa atggaatcag atttgtaaat acttttaacg agctcatcac catcacaatg      360

agtgggaaag tttatgcaaa catcagcagc tacaatgcca gcacatacca gttttttcct      420

tctggcataa aaggcttcac aataagctca acagagattc cgccacaatg tcaacctaat      480

ttcaatactt tctaccttga atttggtagt gcttatacct atatagtcca aaggaagaat      540

gacagctgcc ctgaagtgaa ggtgtttgaa gatatttcag ccaacacagt taacatggct      600

ctgcaa                                                                 606


<210>  5334
<211>  654
<212>  DNA
<213>  Homo Sapiens

<400>  5334
aggaggagcc gaaacaccac caggcccgct ctgctgaggc tgtcggatta ccttttgacc       60

aactacagga agggtgtgcg ccccgtgagg gactggagga agccaaccac cgtatccatt      120

gacgtcattg tctatgccat cctcaacgtg gatgagaaga atcaggtgct gaccacctac      180

atctggtacc ggcagtactg gactgatgag tttctccagt ggaaccctga ggactttgac      240

aacatcacca agttgtccat ccccacggac agcatctggg tcccggacat tctcatcaat      300

gagttcgtgg atgtggggaa gtctccaaat atcccgtacg tgtatattcg gcatcaaggc      360

gaagttcaga actacaagcc ccttcaggtg gtgactgcct gtagcctcga catctacaac      420

ttccccttcg atgtccagaa ctgctcgctg accttcacca gttggctgca caccatccag      480

gacatcaaca tctctttgtg gcgcttgcca gaaaaggtga aatccgacag gagtgtcttc      540

atgaaccagg gagagtggga gttgctgggg gtgctgccct actttcggga gttcagcatg      600

gaaagcagta actactatgc agaaatgaag ttctatgtgg tcatccgccg gcgg            654


<210>  5335
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5335
atggctgaag agggtgtgcc ggcgcccctg cctccagagg acgcccctaa cgccgcatcc       60

ctggcgccca cccctgtgtc ccccgtcctc gagcccttta atctgacttc ggagccctcg      120

gactacgctc tggacctcag cactttcctc cagcaacacc cggccgcctt c               171


<210>  5336
<211>  510
<212>  DNA
<213>  Homo Sapiens

<400>  5336
aggcctaaac ttcctcttag atacccagaa cgccttcaga atccatcaga gagcagtgag       60

cctataccat tagaatcaag agaggaatac atgaatggta tgaacaggca gagaaacatt      120

ctgagagaaa aacagactga tgaaatcaag gatactagga atgagtctac tcagaactgt      180

gttgtggcag agcctgagaa gatggaatcc agcatcagtt catcgagtga ggaaatgtct      240

ctcagtaagt gtgcggaaca gttttgtaga ctgaacgaat acaaccaact tcagctgcaa      300

gctgtccatg cccaggagca aattcgcaga atgaatgaaa acagccatgt ccaagtgcct      360

ttccagcagc tcaaccaact tgctgcctac ccctatgctg tttggtacta tccacaaatc      420

atgcagtatg ttcctttccc accgttttcc gacatctcca atcccactgc tcatgaaaat      480

tatgaaaaaa ataacgtcat gctacagtgg                                       510


<210>  5337
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  5337
agtgtcaatg accctagtaa tatgtcgctg gttaaagaga cggtggatag actcctgaaa       60

ggctatgaca ttcgtctgag accagatttt ggaggtcccc ccgtggctgt ggggatgaac      120

attgacattg ccagcatcga tatggtttct gaagtcaata tggattatac cttgacaatg      180

tactttcaac aagcctggag agataagagg ctgtcctata atgtaatacc tttaaacttg      240

actctggaca acagagtggc agaccagctc tgggtgcctg atacctattt cctgaacgat      300

aagaagtcat ttgtgcacgg agtgactgtt aagaaccgca tgattcgcct gcatcctgat      360

ggcaccgtcc tttatggact cagaatcaca accacagctg cctgcatgat ggacctaagg      420

aggtacccac tggatgaaca aaactgcacc ttggaaattg agagctatgg atacacaact      480

gatgacattg agttttactg gcgtggcgat gataatgcag taacaggagt aacgaaaatt      540

gaacttccac agttctctat tgtagattac aaacttatca ccaagaaggt tgttttttcc      600

acaggttcct atcccaggtt atccctcagc tttaagctta agagaaacat tggctac         657


<210>  5338
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  5338
atgtccaacg tcccccacaa gtcctcgctg cccgagggca tccgccctgg cacggtgctg       60

agaattcgcg gcttggttcc tcccaatgcc agcaggttcc atgtaaacct gctgtgcggg      120

gaggagcagg gctccgatgc cgccctgcat ttcaaccccc ggctggacac gtcggaggtg      180

gtcttcaaca gcaaggagca aggctcctgg ggccgcgagg agcgcgggcc gggcgttcct      240

ttccagcgcg ggcagccctt cgaggtgctc atcatcgcgt cagacgacgg cttcaaggcc      300

gtggttgggg acgcccagta ccaccacttc cgccaccgcc tgccgctggc gcgcgtgcgc      360

ctggtggagg tgggcgggga cgtgcagctg gactccgtga ggatcttc                   408


<210>  5339
<211>  1248
<212>  DNA
<213>  Homo Sapiens

<400>  5339
ggggcccagg acagcccggc gcccggtagc cgcttcgtgt gcacggcact gcccccagag       60

gcggtgcacg ccggctgccc gctgcccgcg atgcccatgc agggcggcgc gcagagtccc      120

gaggaggagc tgagggccgc ggtgctgcag ctgcgcgaga ccgtcgtgca gcagaaggag      180

acgctgggcg cgcagcgcga ggccatccgc gagctcacgg gcaagctagc gcgctgcgag      240

gggctggcgg gcggcaaggc gcgcggcgcg ggggccacgg gcaaggacac tatgggcgac      300

ctgccgcggg accccggcca cgtcgtggag cagctcagcc gctcgctgca gaccctcaag      360

gaccgcctgg agagcctcga gcaccagctc agagcaaacg tgtccaatgc tgggctgccc      420

ggcgacttcc gcgaggtgct ccagcagcgg ctgggggagc tggagaggca gcttctgcgc      480

aaggtggcag agctggagga cgagaagtcc ctgctgcaca atgagacctc ggctcaccgg      540

cagaagaccg agagcaccct gaacgcgctg ctgcagaggg tcaccgagct ggagcgaggc      600

aatagcgcct ttaagtcacc agatgcgttc aaggtgtccc tcccactccg cacaaactac      660

ctatacggca agatcaagaa gacgctgcct gagctgtacg ccttcaccat ctgcctgtgg      720

ctgcggtcca gcgcctcacc aggcattggc acccccttct cctatgcggt gccagggcag      780

gccaacgaga tcgtgctgat cgagtggggc aacaacccca tcgagctgct catcaacgac      840

aaggttgcgc agctgcccct gtttgtcagt gacggcaagt ggcaccacat ctgtgtcacc      900

tggacgacac gggatggcat gtgggaggca ttccaggacg gagagaagct gggcactggg      960

gagaacctgg ccccctggca ccccatcaag cccgggggcg tgctgatcct tggacaagag     1020

caggacaccg tggggggtag gtttgatgcc actcaggcat ttgtcgggga gctcagccag     1080

ttcaacatat gggaccgcgt ccttcgcgca caagaaattg tcaacatcgc caactgctcc     1140

acaaacatgc cgggcaacat catcccgtgg gtggacaata acgtcgatgt gttcggaggg     1200

gcctccaagt ggcccgtgga gacgtgtgag gagcgtctcc ttgacttg                  1248


<210>  5340
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  5340
gtcaagtcct ttaccaccac gctgccctgg gccacatgtg gccacacctg gaacactccc       60

gactgcgtgg agatcttccg ccatgaagac tgtgccaatg ccagcctggc caacctcacc      120

tgtgaccagc ttgctgaccg ccggtcccct gtcatcgagt tctgggagaa caaagtcttg      180

aggctgtctg ggggactgga ggtgccaggg gcc                                   213


<210>  5341
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  5341
agtggtaact tcaattttgg ggcctaccat accctggaag agatttccca agaaatggat       60

aacctcgtgg ctgagcaccc tggtctagtg agcaaagtga atattggctc ttcttttgag      120

aaccggccta tgaacgtgct caagttcagc accggaggag acaagccagc tatctggctg      180

gatgctggga tccatgctcg agagtgggtt acacaagcta cggcactttg gacagcaaat      240

aagattgttt ctgattatgg aaaggaccca tccatcactt ccattctgga cgccctggat      300

atcttcctcc tgccagtcac aaaccctgat ggatacgtgt tctctcaaac caaaaatcgt      360

atgtggcgga agacccggtc caaggtatct ggaagcctct gtgttggtgt ggatcctaac      420

cggaactggg atgcaggttt tggaggacct ggagccagca gcaacccttg ctctgattca      480

taccacggac ccagtgccaa ctctgaagtt gaagtgaaat ccatagtgga cttcatcaag      540

agtcatggaa aagtcaaggc cttcattacc ctccacagct attcccagct tctgatgttc      600

ccctatgggt acaaatgtac caagttagat gactttgatg agctgagtga agtggcccaa      660

aaggctgccc aatctctgag aagcctgcat ggcaccaagt acaaagtggg accaatctgc      720

tctgtcatct accaagccag tggaggaagc attgactggt cctatgatta tggcatcaag      780

tactcatttg cctttgaact gagagacaca gggcgctacg gcttcctctt gccagcccgt      840

cagatcctgc ccacagccga ggagacctgg cttggcttga aggcaatcat ggagcatgtg      900

cgagaccacc cctat                                                       915


<210>  5342
<211>  633
<212>  DNA
<213>  Homo Sapiens

<400>  5342
gcaaatattt tgccagatat cgaaaatgaa gatttcatca aagactgcgt tcgaatccat       60

aacaagttcc gatcagaggt gaaaccaaca gccagtgata tgctatacat gacttgggac      120

ccagcactag cccaaattgc aaaagcatgg gccagcaatt gccagttttc acataataca      180

cggctgaagc caccccacaa gctgcaccca aacttcactt cactgggaga gaacatctgg      240

actgggtctg tgcccatttt ttctgtgtct tccgccatca caaactggta tgacgaaatc      300

caggactatg acttcaagac tcggatatgc aaaaaagtct gtggccacta cactcaggtt      360

gtttgggcag atagttacaa agttggctgc gcagttcaat tttgccctaa agtttctggc      420

tttgacgctc tttccaatgg agcacatttt atatgcaact acggaccagg agggaattac      480

ccaacttggc catataagag aggagccacc tgcagtgcct gccccaataa tgacaagtgt      540

ttggacaatc tctgtgttaa ccgacagcga gaccaagtca aacgttacta ctctgttgta      600

tatccaggct ggcccatata tccacgtaac aga                                   633


<210>  5343
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5343
gcctgggctc tcttctacct gttcagctcc ttcacttctg agctgccctg gacgacctgc       60

aacaactttt ggaacacaga gcattgcacg gactttctga accactcagg agccggcaca      120

gtgaccccat ttgagaattt tacctcacct gtcatggaat tctgggagag acgagttctg      180

ggcatcacct cgggcatcca tgacctgggc tccctgcgc                             219


<210>  5344
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  5344
gcatgggcca ttttttacct gagcaactgc ttcactactg agctaccctg ggctacctgt       60

gggcatgagt ggaacacaga gaattgtgtg gagttccaga aactgaatgt gagcaactac      120

agccatgtgt ctctgcagaa tgccacctcc cctgtcatgg agttttggga gcaccgggtc      180

ctggccatct ctgacgggat cgagcacatc gggaaccttc gc                         222


<210>  5345
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5345
tcgtccatga cgcacgtgct gccctgggcc tactgcaata acccctggaa cacgcatgac       60

tgcgccggtg tactggacgc ctccaacctc accaatggct ctcggccagc cgccttgccc      120

agcaacctct cccacctgct caaccacagc ctccagagga ccagccccag cgaggagtac      180

tggaggctgt acgtgctgaa gctgtcagat gacattggga actttgggga g               231


<210>  5346
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  5346
aaggaaaagt cttcaaagaa agggaagggg aaaaagaagc agtatctatg cccatctcag       60

cagtcagcag aggaccttgc ccgagtacct gccaactcca ctagcaatat cttgaacagg      120

ttattggtca gttatgatcc caggataaga ccaaacttca aaggcattcc tgttgatgta      180

gtagtcaaca tttttattaa cagttttgga tccattcaag aaacaacaat ggactataga      240

gttaacatct tcctgagaca aaaatggaat gaccccaggc tgaagctccc cagtgatttt      300

aggggttcag atgcactgac agtggatcca acaatgtaca agtgtttatg gaaacctgat      360

ttattttttg caaatgaaaa aagtgccaat tttcatgatg tgacccagga aaacatcctc      420

ctctttattt ttcgtgatgg agatgtcctt gtcagcatga ggttatctat tactctttca      480

tgccctttgg acttgacatt gtttcccatg gatacacaac gttgcaagat gcaactggag      540

agctttggtt acacaactga tgatttacga tttatctggc agtcaggaga tcctgtgcaa      600

ttagaaaaaa ttgccttgcc tcaatttgat atcaaaaagg aagatattga atatggtaac      660

tgtacaaaat actataaagg cacgggctac tacacatgcg tggaagtcat cttcaccctg      720

aggaggcagg tcggcttt                                                    738


<210>  5347
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5347
cagaaccaaa aggaggagaa attgtgcaca gaaaatttca cccgcatcct ggacagtttg       60

ctcgatggtt atgacaacag gctgcgtcct ggatttgggg gtcctgttac agaagtgaaa      120

actgacatat atgtcaccag ctttggacct gtttctgatg ttgaaatgga atacacaatg      180

gatgtgttct tcaggcagac atggattgac aaaagattaa aatatgacgg ccccattgaa      240

attttgagat tgaacaatat gatggtaacg aaagtgtgga cccctgatac tttcttcagg      300

aatggaaaga aatctgtctc acataatatg acagctccaa ataagctttt tagaattatg      360

agaaatggta ctattttata cacaatgaga ctcaccataa gtgcggagtg tcccatgaga      420

ttggtggatt ttcccatgga tggtcatgca tgccctttga aattcgggag ttatgcctat      480

ccaaagagtg agatgatcta tacctggaca aaaggtcctg agaaatcagt tgaagttccg      540

aaggagtctt ccagcttagt tcaatatgat ttgattgggc aaaccgtatc aagtgaaacc      600

atcaaatcaa ttacgggtga atatattgtt atgacggttt acttccacct cagacggaag      660

atgggttat                                                              669


<210>  5348
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  5348
gatgctgctc aggagccaac aggaaataac gcggagatct gtctcctgcc cctagactac       60

ggaccctgcc gggccctact tctccgttac tactacgaca ggtacacgca gagctgccgc      120

cagttcctgt acgggggctg cgagggcaac gccaacaatt tctacacctg ggaggcttgc      180

gacgatgctt gctggaggat agaaaaagtt cccaaagttt gccggctgca agtgagtgtg      240

gacgaccagt gtgaggggtc cacagaaaag tatttcttta atctaagttc catgacatgt      300

gaaaaattct tttccggtgg gtgtcaccgg aaccggattg agaacaggtt tccagatgaa      360

gctacttgta tgggcttctg cgcaccaaag aaaattccat cattttgcta cagtccaaaa      420

gatgagggac tgtgctctgc caatgtgact cgctattatt ttaatccaag atacagaacc      480

tgtgatgctt tcacctatac tggctgtgga gggaatgaca ataactttgt tagcagggag      540

gattgcaaac gtgcatgtgc aaaagctttg aaaaagaaaa agaagatgcc aaagcttcgc      600

tttgccagta gaatccggaa aattcggaag aagcaattt                             639


<210>  5349
<211>  1347
<212>  DNA
<213>  Homo Sapiens

<400>  5349
caacagtatt taccattgcc tactcctaaa gtgattggta ttgatcttgg caccacctat       60

tgttctgttg gggtgttttt tcctggcaca ggaaaagtaa aggtgattcc agatgaaaat      120

gggcatatca gcatacccag catggtgtct tttactgaca atgatgtata tgtgggatat      180

gaaagcgtag agctggcaga ttcaaatcct caaaacacaa tatatgatgc caaaagattc      240

ataggcaaga tttttaccgc agaagagttg gaggctgaaa ttggcagata cccatttaag      300

gttttaaaca aaaatggaat ggttgagttt tctgtgacaa gtaatgagac catcacagtg      360

tccccagaat atgttggctc tcgactattg ttgaagttaa aggaaatggc agaggcatat      420

cttggaatgc cagttgccaa tgctgtcatt tctgtaccag cagaatttga tctaaaacag      480

agaaattcaa caattgaagc tgctaacctt gcaggactga agattttgag ggtaataaat      540

gaacccacag cagcagctat ggcctatggt ctccacaagg ctgacgtctt ccacgtcttg      600

gtgatagact tgggcggagg aactctagat gtgtctttac tgaataaaca aggagggatg      660

tttctaaccc gagcaatgtc tggaaacaat aaacttggag gacaggactt caatcagaga      720

ttgcttcagt acttatataa acagatctat caaacatatg gcttcgtgcc ctctaggaaa      780

gaggaaatcc acagattgag acaagctgtg gaaatggtca aattaaatct gactcttcat      840

caatctgctc agttgtcagt attactaacg gtggaggagc aggacaggaa ggaacctcac      900

agtagtgaca ctgaactgcc aaaagacaaa ctttcctcag cagatgacca tcgcgtgaac      960

agtgggtttg gacgtggcct ttctgataag aaaagtggag aaagtcaggt tttatttgaa     1020

acagaaatat cacggaaact ctttgatacc cttaatgaag acctctttca gaaaatactg     1080

gtacccattc agcaagtatt gaaagaaggc cacctggaaa agactgagat tgatgaggtg     1140

gttttagttg ggggctccac tcgtattcct cggatccgtc aagtcattca agagttcttt     1200

ggaaaagatc ccaacacatc tgtagaccct gacctagcag tagtaacggg agtggctatc     1260

caagcaggga ttgatggagg cttttggcct ctccaagtca gtgctttaga aattcccaat     1320

aagcatttac aaaaaaccaa cttcaac                                         1347


<210>  5350
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  5350
actcagcgct gccctcccca gtgcccgggc cggtgccctg cgacgccgcc gacctgcgcc       60

cccggggtgc gcgcggtgct ggacggctgc tcatgctgtc tggtgtgtgc ccgccagcgt      120

ggcgagagct gctcagatct ggagccatgc gacgagagca gtggcctcta ctgtgatcgc      180

agcgcggacc ccagcaaaca gactggcatc tgcacggcgg tagagggaga taactgtgtg      240

ttcgatgggg tcatctaccg cagtggagag aaatttcagc caagctgcaa attccagtgc      300

acctgcagag atgggcagat tggctgtgtg ccccgctgtc agctggatgt gctactgcct      360

gagcctaact gcccagctcc aagaaaagtt gaggtgcctg gagagtgctg tgaaaagtgg      420

atctgtggcc cagatgagga ggattcactg ggaggcctta cccttgcagc ttacaggcca      480

gaagccaccc taggagtaga agtctctgac tcaagtgtca actgcattga acagaccaca      540

gagtggacag catgctccaa gagctgtggt atggggttct ccacccgggt caccaatagg      600

aaccgtcaat gtgagatgct gaaacagact cggctctgca tggtgcggcc ctgtgaacaa      660

gagccagagc agccaacaga taagaaagga aaaaagtgtc tccgcaccaa gaagtcactc      720

aaagccatcc acctgcagtt caagaactgc accagcctgc acacctacaa gcccaggttc      780

tgtggggtct gcagtgatgg ccgctgctgc actccccaca ataccaaaac catccaggca      840

gagtttcagt gctccccagg gcaaatagtc aagaagccag tgatggtcat tgggacctgc      900

acctgtcaca ccaactgtcc taagaacaat gaggccttcc tccaggagct ggagctgaag      960

actaccagag ggaaaatg                                                    978


<210>  5351
<211>  192
<212>  DNA
<213>  Homo Sapiens

<400>  5351
gctcacaaca agtttcatga ttttgctgat cggaaggatt gggatgcatt ccatcctaca       60

ctggtggcag aagggctttt tgcatttgca aatgttctaa gttatcttcg tctctttttt      120

atgtatacaa ccagctctat cttgggtcca ttacagattt caatgggaca gatgttacaa      180

gattttggaa aa                                                          192


<210>  5352
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  5352
tttcgcatct gcgccttcaa tgcccagcgg ctgacactgg ccaaggtggc cagggagcag       60

gtgatggaca ccttagttcg gatactggct cgctgtgaca tcatggtgct gcaggaggtg      120

gtggactctt ccggcagcgc catcccgctc ctgcttcgag aactcaatcg atttgatggc      180

tctgggccct acagcaccct gagcagcccc cagctggggc gcagcaccta catggagacg      240

tatgtgtact tctatcggtc acacaaaaca caggtcctga gttcctacgt gtacaacgat      300

gaggatgacg tctttgcccg ggagccattt gtggcccagt tctctttgcc cagcaatgtc      360

cttcccagcc tggtgttggt cccgctgcac accactccta aggccgtaga gaaggagctg      420

aacgccctct acgatgtgtt tctggaggtc tcccagcact ggcagagcaa ggacgtgatc      480

ctgcttgggg acttcaatgc tgactgcgct tcactgacca aaaagcgcct ggacaagctg      540

gagctgcgga ctgagccagg cttccactgg gtgattgccg atggggagga caccacagtg      600

cgggccagca cccactgcac ctatgaccgc gtcgtgctgc acggggagcg ctgccggagt      660

ctgctgcaca ctgcggctgc ctttgacttc cccacgagct tccagctcac cgaggaggag      720

gccctcaaca tcagtgacca ctaccccgtg gaggtggagc tgaagctgag ccaggcgcac      780

agcgtccagc ctctcagcct cactgttctg ttgctgctat cactcctgtc ccctcagctg      840

tgccctgctg cc                                                          852


<210>  5353
<211>  1131
<212>  DNA
<213>  Homo Sapiens

<400>  5353
atggcagaag gcaaccacag aaaaaagcca cttaaggtgt tggaatccct gggcaaagat       60

ttcctcactg gtgttttgga taacttggtg gaacaaaatg tactgaactg gaaggaagag      120

gaaaaaaaga aatattacga tgctaaaact gaagacaaag ttcgggtcat ggcagactct      180

atgcaagaga agcaacgtat ggcaggacaa atgcttcttc aaaccttttt taacatagac      240

caaatatccc ccaataaaaa agctcatccg aatatggagg ctggaccacc tgagtcagga      300

gaatctacag atgccctcaa gctttgtcct catgaagaat tcctgagact atgtaaagaa      360

agagctgaag agatctatcc aataaaggag agaaacaacc gcacacgcct ggctctcatc      420

atatgcaata cagagtttga ccatctgcct ccgaggaatg gagctgactt tgacatcaca      480

gggatgaagg agctacttga gggtctggac tatagtgtag atgtagaaga gaatctgaca      540

gccagggata tggagtcagc gctgagggca tttgctacca gaccagagca caagtcctct      600

gacagcacat tcttggtact catgtctcat ggcatcctgg agggaatctg cggaactgtg      660

catgatgaga aaaaaccaga tgtgctgctt tatgacacca tcttccagat attcaacaac      720

cgcaactgcc tcagtctgaa ggacaaaccc aaggtcatca ttgtccaggc ctgcagaggt      780

gcaaaccgtg gggaactgtg ggtcagagac tctccagcat ccttggaagt ggcctcttca      840

cagtcatctg agaacctgga ggaagatgct gtttacaaga cccacgtgga gaaggacttc      900

attgctttct gctcttcaac gccacacaac gtgtcctgga gagacagcac aatgggctct      960

atcttcatca cacaactcat cacatgcttc cagaaatatt cttggtgctg ccacctagag     1020

gaagtatttc ggaaggtaca gcaatcattt gaaactccaa gggccaaagc tcaaatgccc     1080

accatagaac gactgtccat gacaagatat ttctacctct ttcctggcaa t              1131


<210>  5354
<211>  474
<212>  DNA
<213>  Homo Sapiens

<400>  5354
acccaggact gctccttcca acacagcccc atctcctccg acttcgctgt caaaatccgt       60

gagctgtctg actacctgct tcaagattac ccagtcaccg tggcctccaa cctgcaggac      120

gaggagctct gcgggggcct ctggcggctg gtcctggcac agcgctggat ggagcggctc      180

aagactgtcg ctgggtccaa gatgcaaggc ttgctggagc gcgtgaacac ggagatacac      240

tttgtcacca aatgtgcctt tcagcccccc cccagctgtc ttcgcttcgt ccagaccaac      300

atctcccgcc tcctgcagga gacctccgag cagctggtgg cgctgaagcc ctggatcact      360

cgccagaact tctcccggtg cctggagctg cagtgtcagc ccgactcctc aaccctgcca      420

cccccatgga gtccccggcc cctggaggcc acagccccga cagccccgca gccc            474


<210>  5355
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5355
attattgatg gcgccccatg tgcaagaggc tcccacccat ggcaggtggc cctgctcagt       60

ggcaatcagc tccactgcgg aggcgtcctg gtcaatgagc gctgggtgct cactgccgcc      120

cactgcaaga tgaatgagta caccgtgcac ctgggcagtg atacgctggg cgacaggaga      180

gctcagagga tcaaggcctc gaagtcattc cgccaccccg gctactccac acagacccat      240

gttaatgacc tcatgctcgt gaagctcaat agccaggcca ggctgtcatc catggtgaag      300

aaagtcaggc tgccctcccg ctgcgaaccc cctggaacca cctgtactgt ctccggctgg      360

ggcactacca cgagcccaga tgtgaccttt ccctctgacc tcatgtgcgt ggatgtcaag      420

ctcatctccc cccaggactg cacgaaggtt tacaaggact tactggaaaa ttccatgctg      480

tgcgctggca tccccgactc caagaaaaac gcctgcaatg gtgactcagg gggaccgttg      540

gtgtgcagag gtaccctgca aggtctggtg tcctggggaa ctttcccttg cggccaaccc      600

aatgacccag gagtctacac tcaagtgtgc aagttcacca agtggataaa tgacaccatg      660

aaaaagcatc gc                                                          672


<210>  5356
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  5356
attattggag ggaaagaagt gtcacctcat tccaggccat ttatggcctc catccagtat       60

ggcggacatc acgtttgtgg aggtgttctg attgatccac agtgggtgct gacagcagcc      120

cactgccaat atcggtttac caaaggccag tctcccactg tggttttagg cgcacactct      180

ctctcaaaga atgaggcctc caaacaaaca ctggagatca aaaaatttat accattctca      240

agagttacat cagatcctca atcaaatgat atcatgctgg ttaagcttca aacagccgca      300

aaactcaata aacatgtcaa gatgctccac ataagatcca aaacctctct tagatctgga      360

accaaatgca aggttactgg ctggggagcc accgatccag attcattaag accttctgac      420

accctgcgag aagtcactgt tactgtccta agtcgaaaac tttgcaacag ccaaagttac      480

tacaacggcg acccttttat caccaaagac atggtctgtg caggagatgc caaaggccag      540

aaggattcct gtaagggtga ctcagggggc cccttgatct gtaaaggtgt cttccacgct      600

atagtctctg gaggtcatga atgtggtgtt gccacaaagc ctggaatcta caccctgtta      660

accaagaaat accagacttg gatcaaaagc aaccttgtcc cgcctcatac aaat            714


<210>  5357
<211>  1290
<212>  DNA
<213>  Homo Sapiens

<400>  5357
tacgccatcc agggtctcaa atggcaacat aatgaaatca ctttctgcat ccagaattac       60

acccccaagg tgggcgagta tgccacatac gaggccattc gcaaggcgtt ccgcgtgtgg      120

gagagtgcca caccactgcg cttccgcgag gtgccctatg cctacatccg tgagggccat      180

gagaagcagg ccgacatcat gatcttcttt gccgagggct tccatggcga cagcacgccc      240

ttcgatggtg agggcggctt cctggcccat gcctacttcc caggccccaa cattggagga      300

gacacccact ttgactctgc cgagccttgg actgtcagga atgaggatct gaatggaaat      360

gacatcttcc tggtggctgt gcacgagctg ggccatgccc tggggctcga gcattccagt      420

gacccctcgg ccatcatggc acccttttac cagtggatgg acacggagaa ttttgtgctg      480

cccgatgatg accgccgggg catccagcaa ctttatgggg gtgagtcagg gttccccacc      540

aagatgcccc ctcaacccag gactacctcc cggccttctg ttcctgataa acccaaaaac      600

cccacctatg ggcccaacat ctgtgacggg aactttgaca ccgtggccat gctccgaggg      660

gagatgtttg tcttcaagga gcgctggttc tggcgggtga ggaataacca agtgatggat      720

ggatacccaa tgcccattgg ccagttctgg cggggcctgc ctgcgtccat caacactgcc      780

tacgagagga aggatggcaa attcgtcttc ttcaaaggag acaagcattg ggtgtttgat      840

gaggcgtccc tggaacctgg ctaccccaag cacattaagg agctgggccg agggctgcct      900

accgacaaga ttgatgctgc tctcttctgg atgcccaatg gaaagaccta cttcttccgt      960

ggaaacaagt actaccgttt caacgaagag ctcagggcag tggatagcga gtaccccaag     1020

aacatcaaag tctgggaagg gatccctgag tctcccagag ggtcattcat gggcagcgat     1080

gaagtcttca cttacttcta caaggggaac aaatactgga aattcaacaa ccagaagctg     1140

aaggtagaac cgggctaccc caagtcagcc ctgagggact ggatgggctg cccatcggga     1200

ggccggccgg atgaggggac tgaggaggag acggaggtga tcatcattga ggtggacgag     1260

gagggcggcg gggcggtgag cgcggctgcc                                      1290


<210>  5358
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  5358
atgtcttcag aaagtaaaga gcaacataac gtttcaccca gagactcagc tgaaggaaat       60

gacagttatc catctgggat ccatctggaa cttcaaaggg aatcaagtac tgacttcaag      120

caatttgaga ccaatgatca atgcagacct tatcatagga tccttattga gcgtcaagag      180

aaatcagata caaacttcaa ggagtttgtt attaaaaagc tgcagaagaa ttgccagtgc      240

agtccagcca aagccaaaaa tatgatttta ggtttccttc ctgttttgca gtggctccca      300

aaatacgacc taaagaaaaa cattttaggg gat                                   333


<210>  5359
<211>  1200
<212>  DNA
<213>  Homo Sapiens

<400>  5359
gccgaggtga agaaacctgc agccgcagca gctcctggca ctgcggagaa gttgagcccc       60

aaggcggcca cgcttgccga gcgcagcgcc ggcctggcct tcagcttgta ccaggccatg      120

gccaaggacc aggcagtgga gaacatcctg gtgtcacccg tggtggtggc ctcgtcgctg      180

gggctcgtgt cgctgggcgg caaggcgacc acggcgtcgc aggccaaggc agtgctgagc      240

gccgagcagc tgcgcgacga ggaggtgcac gccggcctgg gcgagctgct gcgctcactc      300

agcaactcca cggcgcgcaa cgtgacctgg aagctgggca gccgactgta cggacccagc      360

tcagtgagct tcgctgatga cttcgtgcgc agcagcaagc agcactacaa ctgcgagcac      420

tccaagatca acttccgcga caagcgcagc gcgctgcagt ccatcaacga gtgggccgcg      480

cagaccaccg acggcaagct gcccgaggtc accaaggacg tggagcgcac ggacggcgcc      540

ctgttagtca acgccatgtt cttcaagcca cactgggatg agaaattcca ccacaagatg      600

gtggacaacc gtggcttcat ggtgactcgg tcctataccg tgggtgtcat gatgatgcac      660

cggacaggcc tctacaacta ctacgacgac gagaaggaaa agctgcaaat cgtggagatg      720

cccctggccc acaagctctc cagcctcatc atcctcatgc cccatcacgt ggagcctctc      780

gagcgccttg aaaagctgct aaccaaagag cagctgaaga tctggatggg gaagatgcag      840

aagaaggctg ttgccatctc cttgcccaag ggtgtggtgg aggtgaccca tgacctgcag      900

aaacacctgg ctgggctggg cctgactgag gccattgaca agaacaaggc cgacttgtca      960

cgcatgtcag gcaagaagga cctgtacctg gccagcgtgt tccacgccac cgcctttgag     1020

ttggacacag atggcaaccc ctttgaccag gacatctacg ggcgcgagga gctgcgcagc     1080

cccaagctgt tctacgccga ccaccccttc atcttcctag tgcgggacac ccaaagcggc     1140

tccctgctat tcattgggcg cctggtccgg cctaagggtg acaagatgcg agacgagtta     1200


<210>  5360
<211>  837
<212>  DNA
<213>  Homo Sapiens

<400>  5360
gacccgccgg cgccgctgcc gttggtgatc tggcatggga tgggagacag ctgttgcaat       60

cccttaagca tgggtgctat taaaaaaatg gtggagaaga aaatacctgg aatttacgtc      120

ttatctttag agattgggaa gaccctgatg gaggacgtgg agaacagctt cttcttgaat      180

gtcaattccc aagtaacaac agtgtgtcag gcacttgcta aggatcctaa attgcagcaa      240

ggctacaatg ctatgggatt ctcccaggga ggccaatttc tgagggcagt ggctcagaga      300

tgcccttcac ctcccatgat caatctgatc tcggttgggg gacaacatca aggtgttttt      360

ggactccctc gatgcccagg agagagctct cacatctgtg acttcatccg aaaaacactg      420

aatgctgggg cgtactccaa agttgttcag gaacgcctcg tgcaagccga atactggcat      480

gaccccataa aggaggatgt gtatcgcaac cacagcatct tcttggcaga tataaatcag      540

gagcggggta tcaatgagtc ctacaagaaa aacctgatgg ccctgaagaa gtttgtgatg      600

gtgaaattcc tcaatgattc cattgtggac cctgtagatt cggagtggtt tggattttac      660

agaagtggcc aagccaagga aaccattccc ttacaggaga cctccctgta cacacaggac      720

cgcctggggc taaaggaaat ggacaatgca ggacagctag tgtttctggc tacagaaggg      780

gaccatcttc agttgtctga agaatggttt tatgcccaca tcataccatt ccttgga         837


<210>  5361
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  5361
atcatcgggg gccgggaggt gatcccccac tcgcgcccgt acatggcctc actgcagaga       60

aatggctccc acctgtgcgg gggtgtcctg gtgcacccaa agtgggtgct gacggctgcc      120

cactgcctgg cccagcggat ggcccagctg aggctggtgc tggggctcca caccctggac      180

agccccggtc tcaccttcca catcaaggca gccatccagc accctcgcta caagcccgtc      240

cctgccctgg agaacgacct cgcgctgctt cagctggacg ggaaagtgaa gcccagccgg      300

accatccggc cgttggccct gcccagtaag cgccaggtgg tggcagcagg gactcggtgc      360

agcatggccg gctgggggct gacccaccag ggcgggcgcc tgtcccgggt gctgcgggag      420

ctggacctcc aagtgctgga cacccgcatg tgtaacaaca gccgcttctg gaacggcagc      480

ctctccccca gcatggtctg cctggcggcc gactccaagg accaggctcc ctgcaagggt      540

gactcgggcg ggcccctggt gtgtggcaaa ggccgggtgt tggccggagt cctgtccttc      600

agctccaggg tctgcactga catcttcaag cctcccgtgg ccaccgctgt ggcgccttac      660

gtgtcctgga tcaggaaggt caccggccga tcggcc                                696


<210>  5362
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5362
tgcctctatg tgctgatgca gacagtggac ccgtacacac cggactacca agaccagcta       60

cggtcaccag gggtaacctt aaggccggat gtttacgggg agaaaggcct ggaaattgtc      120

tacaacgtct ctgataacag aacctgggca gacctcacac agactctcca cgccttccta      180

gcaggctact ctccagcagc ccaggaggac agcatcaact gcacctccga gcagtacttc      240

ttccaggaga gtttccgcgc tcccaaccac accaagttct cctgcaagtt cacggcagat      300

atgctgcaga actgctcagg cctggcggat cccaacttcg gctttgaaga aggaaagcca      360

tgttttatta ttaaaatgaa caggatcgtc aagttcctcc ccagcaacgg ctcggccccc      420

agagtggact gcgccttcct ggaccagccc cgcgagctcg gccagccgct gcaggtcaag      480

tactaccctc ccaacggcac cttcagtctg cactacttcc cttattacgg gaagaaagcc      540

cagccccact acagcaaccc cctggtggca gcgaagctcc tcaacatccc caggaacgct      600

gaggtcgcca tcgtgtgcaa ggtcatggca gagcacgtga ccttcaacaa tccccacgac      660

ccgtatgaag ggaaagtgga gttcaaactc aagattgaga ag                         702


<210>  5363
<211>  1383
<212>  DNA
<213>  Homo Sapiens

<400>  5363
aggacctact tgagctggga ggtcagcgtc tccctctccg taggcttcaa gaccatggac       60

ttccctgccg tcaccatctg caatgctagc cccttcaagt attccaaaat caagcatttg      120

ctgaaggacc tggatgagct gatggaagct gtcctggaga gaatcctggc tcctgagcta      180

agccatgcca atgccaccag gaacctgaac ttctccatct ggaaccacac acccctggtc      240

cttattgatg aacggaaccc ccaccacccc atggtccttg atctctttgg agacaaccac      300

aatggcttaa caagcagctc agcatcagaa aagatctgta atgcccacgg gtgcaaaatg      360

gccatgagac tatgtagcct caacaggacc cagtgtacct tccggaactt caccagtgct      420

acccaggcat tgacagagtg gtacatcctg caggccacca acatctttgc acaggtgcca      480

cagcaggagc tagtagagat gagctacccc ggcgagcaga tgatcctggc ctgcctattc      540

ggagctgagc cctgcaacta ccggaacttc acgtccatct tctaccctca ctatggcaac      600

tgttacatct tcaactgggg catgacagag aaggcacttc cttcggccaa ccctggaact      660

gaattcggcc tgaagttgat cctggacata ggccaggaag actacgtccc cttccttgcg      720

tccacggccg gggtcaggct gatgcttcac gagcagaggt catacccctt catcagagat      780

gagggcatct acgccatgtc ggggacagag acgtccatcg gggtactcgt ggacaagctt      840

cagcgcatgg gggagcccta cagcccgtgc accgtgaatg gttctgaggt ccccgtccaa      900

aacttctaca gtgactacaa cacgacctac tccatccagg cctgtcttcg ctcctgcttc      960

caagaccaca tgatccgtaa ctgcaactgt ggccactacc tgtacccact gccccgtggg     1020

gagaaatact gcaacaaccg ggacttccca gactgggccc attgctactc agatctacag     1080

atgagcgtgg cgcagagaga gacctgcatt ggcatgtgca aggagtcctg caatgacacc     1140

cagtacaaga tgaccatctc catggctgac tggccttctg aggcctccga ggactggatt     1200

ttccacgtct tgtctcagga gcgggaccaa agcaccaata tcaccctgag caggaaggga     1260

attgtcaagc tcaacatcta cttccaagaa tttaactatc gcaccattga agaatcagca     1320

gccaataaca tcgtctggct gctctcgaat ctgggtggcc agtttggctt ctggatgggg     1380

ggc                                                                   1383


<210>  5364
<211>  1395
<212>  DNA
<213>  Homo Sapiens

<400>  5364
tccttctata ctgtctcagt ttccatcaaa gtccacttcc ggaagctgga ttttcctgca       60

gtcaccatct gcaacatcaa cccctacaag tacagcaccg ttcgccacct tctagctgac      120

ttggaacagg agaccagaga ggccctgaag tccctgtatg gctttccaga gtcccggaag      180

cgccgagagg cggagtcctg gaactccgtc tcagagggaa agcagcctag attctcccac      240

cggattccgc tgctgatctt tgatcaggat gagaagggca aggccaggga cttcttcaca      300

gggaggaagc ggaaagtcgg cggtagcatc attcacaagg cttcaaatgt catgcacatc      360

gagtccaagc aagtggtggg attccaactg tgctcaaatg acacctccga ctgtgccacc      420

tacaccttca gctcgggaat caatgccatt caggagtggt ataagctaca ctacatgaac      480

atcatggcac aggtgcctct ggagaagaaa atcaacatga gctattctgc tgaggagctg      540

ctggtgacct gcttctttga tggagtgtcc tgtgatgcca ggaatttcac gcttttccac      600

cacccgatgc atgggaattg ctatactttc aacaacagag aaaatgagac cattctcagc      660

acctccatgg ggggcagcga atatgggctg caagtcattt tgtacataaa cgaagaggaa      720

tacaacccat tcctcgtgtc ctccactgga gctaaggtga tcatccatcg gcaggatgag      780

tatcccttcg tcgaagatgt gggaacagag attgagacag caatggtcac ctctatagga      840

atgcacctga cagagtcctt caagctgagt gagccctaca gtcagtgcac ggaggacggg      900

agtgacgtgc caatcaggaa catctacaac gctgcctact cgctccagat ctgccttcat      960

tcatgcttcc agacaaagat ggtggagaaa tgtgggtgtg cccagtacag ccagcctcta     1020

cctcctgcag ccaactactg caactaccag cagcacccca actggatgta ttgttactac     1080

caactgcatc gagcctttgt ccaggaagag ctgggctgcc agtctgtgtg caaggaagcc     1140

tgcagcttta aagagtggac actaaccaca agcctggcac aatggccatc tgtggtttcg     1200

gagaagtggt tgctgcctgt tctcacttgg gaccaaggcc ggcaagtaaa caaaaagctc     1260

aacaagacag acttggccaa actcttgata ttctacaaag acctgaacca gagatccatc     1320

atggagagcc cagccaacag tattgagatg cttctgtcca acttcggtgg ccagctgggc     1380

ctgtggatga gctgc                                                      1395


<210>  5365
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  5365
tatgagaagg gctaccagac ctcgagcggc ctcatcagca gtgtctctgt gaaactcaag       60

ggcctggccg tgacccagct ccctggcctc ggcccccagg tctgggatgt ggctgactac      120

gtcttcccag cccaggggga caactccttc gtggtcatga ccaatttcat cgtgaccccg      180

aagcagactc aaggctactg cgcagagcac ccagaagggg gcatatgcaa ggaagacagt      240

ggctgtaccc ctgggaaggc caagaggaag gcccaaggca tccgcacggg caagtgtgtg      300

gccttcaacg acactgtgaa gacgtgtgag atctttggct ggtgccccgt ggaggtggat      360

gacgacatcc cgcgccctgc ccttctccga gaggccgaga acttcactct tttcatcaag      420

aacagcatca gctttccacg cttcaaggtc aacaggcgca acctggtgga ggaggtgaat      480

gctgcccaca tgaagacctg cctctttcac aagaccctgc accccctgtg cccagtcttc      540

cagcttggct acgtggtgca agagtcaggc cagaacttca gcaccctggc tgagaagggt      600

ggagtggttg gcatcaccat cgactggcac tgtgacctgg actggcacgt acggcactgc      660

agacccatct atgagttcca tgggctgtac gaagagaaaa atctctcccc aggcttcaac      720

ttcaggtttg ccaggcactt tgtggagaac gggaccaact accgtcacct cttcaaggtg      780

tttgggattc gctttgacat cctggtggac ggcaaggccg ggaagtttga catcatccct      840

acaatgacca ccatcggctc tgga                                             864


<210>  5366
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  5366
cagcccccgc cgccgccgcc ggacgccacc tgtcaccaag tccgctcctt cttccagaga       60

ctgcagcccg gactcaagtg ggtgccagaa actcccgtgc caggatcaga tttgcaagta      120

tgtctcccta agggcccaac atgctgctca agaaagatgg aagaaaaata ccaactaaca      180

gcacgattga acatggaaca gctgcttcag tctgcaagta tggagctcaa gttcttaatt      240

attcagaatg ctgcggtttt ccaagaggcc tttgaaattg ttgttcgcca tgccaagaac      300

tacaccaatg ccatgttcaa gaacaactac ccaagcctga ctccacaagc ttttgagttt      360

gtgggtgaat ttttcacaga tgtgtctctc tacatcttgg gttctgacat caatgtagat      420

gacatggtca atgaattgtt tgacagcctg tttccagtca tctataccca gctaatgaac      480

ccaggcctgc ctgattcagc cttggacatc aatgagtgcc tccgaggagc aagacgtgac      540

ctgaaagtat ttgggaattt ccccaagctt attatgaccc aggtttccaa gtcactgcaa      600

gtcactagga tcttccttca ggctctgaat cttggaattg aagtgatcaa cacaactgat      660

cacctgaagt tcagtaagga ctgtggccga atgctcacca gaatgtggta ctgctcttac      720

tgccagggac tgatgatggt taaaccctgt ggcggttact gcaatgtggt catgcaaggc      780

tgtatggcag gtgtggtgga gattgacaag tactggagag aatacattct gtcccttgaa      840

gaacttgtga atggcatgta cagaatctat gacatggaga acgtactgct tggtctcttt      900

tcaacaatcc atgattctat ccagtatgtc cagaagaatg caggaaagct gaccaccact      960

attggcaagt tatgtgccca ttctcaacaa cgccaatata gatttgctta ttatcctgaa     1020

gatctcttta ttgacaagaa agtattaaaa gttgctcatg tagaacatga agaaacctta     1080

tccagccgaa gaagggaact aattcagaag ttgaagtctt tcatcagctt ctatagtgct     1140

ttgcctggct acatctgcag ccatagccct gtggcggaaa acgacaccct ttgctggaat     1200

ggacaagaac tcgtggagag atacagccaa aaggcagcaa ggaatggaat gaaaaaccag     1260

ttcaatctcc atgagctgaa aatgaagggc cctgagccag tggtcagtca aattattgac     1320

aaactgaagc acattaacca gctcctgaga accatgtcta tgcccaaagg tagagttctg     1380

gataaaaacc tggatgagga agggtttgaa agtggagact gcggtgatga tgaagatgag     1440

tgcattggag gctctggtga tggaatgata aaagtgaaga atcagctccg cttccttgca     1500

gaactggcct atgatctgga tgtggatgat gcgcctggaa acagtcagca ggcaactccg     1560

aaggacaacg agataagcac ctttcacaac ctcgggaacg ttcattcccc gctgaagctt     1620

ctcacc                                                                1626


<210>  5367
<211>  195
<212>  DNA
<213>  Homo Sapiens

<400>  5367
tcactgccag tttacatgta cttcaatctg tggaccatct gccggaacac cacattagtg       60

gagggagcaa atctctgctt ggaccttcgt cagtttggaa ttgtgacaat tggagaggaa      120

aagaaaattt gtactgtctc tgagaatttc ttgaggatgt gcgaatctac tgagctgaac      180

atgaccttcc acttg                                                       195


<210>  5368
<211>  144
<212>  DNA
<213>  Homo Sapiens

<400>  5368
atgacaccca cagacttcac aagccctatt cctaacatgg ctgatgacta tggctctgaa       60

tccacatctt ccatggaaga ctacgttaac ttcaacttca ctgacttcta ctgtgagaaa      120

aacaatgtca ggcagtttgc gagc                                             144


<210>  5369
<211>  1446
<212>  DNA
<213>  Homo Sapiens

<400>  5369
cgtccccgga acgcactgct gctcctcgcg gatgacggag gctttgagag tggcgcgtac       60

aacaacagcg ccatcgccac cccgcacctg gacgccttgg cccgccgcag cctcctcttt      120

cgcaatgcct tcacctcggt cagcagctgc tctcccagcc gcgccagcct cctcactggc      180

ctgccccagc atcagaatgg gatgtacggg ctgcaccagg acgtgcacca cttcaactcc      240

ttcgacaagg tgcggagcct gccgctgctg ctcagccaag ctggtgtgcg cacaggcatc      300

atcgggaaga agcacgtggg gccggagacc gtgtacccgt ttgactttgc gtacacggag      360

gagaatggct ccgtcctcca ggtggggcgg aacatcacta gaattaagct gctcgtccgg      420

aaattcctgc agactcagga tgaccggcct ttcttcctct acgtcgcctt ccacgacccc      480

caccgctgtg ggcactccca gccccagtac ggaaccttct gtgagaagtt tggcaacgga      540

gagagcggca tgggtcgtat cccagactgg accccccagg cctacgaccc actggacgtg      600

ctggtgcctt acttcgtccc caacaccccg gcagcccgag ccgacctggc cgctcagtac      660

accaccgtag gccgcatgga ccaaggagtt ggactggtgc tccaggagct gcgtgacgcc      720

ggtgtcctga acgacacact ggtgatcttc acgtccgaca acgggatccc cttccccagc      780

ggcaggacca acctgtactg gccgggcact gctgaaccct tactggtgtc atccccggag      840

cacccaaaac gctggggcca agtcagcgag gcctacgtga gcctcctaga cctcacgccc      900

accatcttgg attggttctc gatcccgtac cccagctacg ccatctttgg ctcgaagacc      960

atccacctca ctggccggtc cctcctgccg gcgctggagg ccgagcccct ctgggccacc     1020

gtctttggca gccagagcca ccacgaggtc accatgtcct accccatgcg ctccgtgcag     1080

caccggcact tccgcctcgt gcacaacctc aacttcaaga tgccctttcc catcgaccag     1140

gacttctacg tctcacccac cttccaggac ctcctgaacc gcactacagc tggtcagccc     1200

acgggctggt acaaggacct ccgtcattac tactaccggg cgcgctggga gctctacgac     1260

cggagccggg acccccacga gacccagaac ctggccaccg acccgcgctt tgctcagctt     1320

ctggagatgc ttcgggacca gctggccaag tggcagtggg agacccacga cccctgggtg     1380

tgcgcccccg acggcgtcct ggaggagaag ctctctcccc agtgccagcc cctccacaat     1440

gagctg                                                                1446


<210>  5370
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  5370
aaaactgcaa atgcctttaa accaaatatc ctactgatca tggcggatga tctaggcact       60

ggggatctcg gttgctacgg gaacaataca ctgagaacgc cgaatattga ccagcttgca      120

gaggaaggtg tgaggctcac tcagcacctg gcggccgccc cgctctgcac cccaagccga      180

gctgcattcc tcacagggag acattccttc agatcaggca tggacgccag caatggatac      240

cgggcccttc agtggaacgc aggctcaggt ggactccctg agaacgaaac cacttttgca      300

agaatcttgc agcagcatgg ctatgcaacc ggcctcatag gaaaatggca ccagggtgtg      360

aattgtgcat cccgcgggga tcactgccac caccccctga accacggatt tgactatttc      420

tacggcatgc ccttcacgct cacaaacgac tgtgacccag gcaggccccc cgaagtggac      480

gccgccctga gggcgcagct ctggggttac acccagttcc tggcgctggg gattctcacc      540

ctggctgccg gccagacctg cggtttcttc tctgtctccg cgagagcagt caccggcatg      600

gccggcgtgg gctgcctgtt tttcatctct tggtactcct ccttcgggtt tgtgcgacgc      660

tggaactgta ttctgatgag aaaccatgac gtcacggagc aacccatggt tctggagaaa      720

acagcgagtc ttatgctaaa ggaagctgtt tcctatattg aaagacacaa gcatgggcca      780

tttctcctct tcctttcttt gctgcatgtg cacattcccc ttgtgaccac gagtgcattc      840

ctggggaaaa gtcagcatgg cttatatggt gataatgtgg aggagatgga ctggctcata      900

ggtaaggttc ttaatgccat cgaagacaat ggtttaaaga actcaacatt cacgtatttc      960

acctctgacc atggaggaca tttagaggca agagatggac acagccagtt agggggatgg     1020

aacggaattt acaaaggtgg gaagggcatg ggaggatggg aaggtgggat ccgcgtgccc     1080

gggatcttcc actggccggg ggtgctcccg gccggccgag tgattggaga gcccacgagc     1140

ctgatggacg tgttccctac tgtggtccag ctggtgggtg gcgaggtgcc ccaggacagg     1200

gtgattgatg gccacagcct ggtacccttg ctgcagggag ctgaggcacg ctcggcacat     1260

gagttcctgt ttcattactg tgggcagcat cttcacgcag cacgctggca ccagaaggac     1320

agtggaagcg tctggaaggt tcattacacg accccgcagt tccaccccga gggagcgggg     1380

gcctgctacg gccgaggcgt ctgcccatgc tccggggagg gcgtgaccca tcacagaccc     1440

cctttgctct ttgacctctc cagggacccc tccgaggcac ggcccctgac ccccgactcc     1500

gagcccctgt accacgccgt gatagcaagg gtaggtgccg cggtgtcgga gcatcggcag     1560

accctgagtc ctgtgcccca gcagttttcc atgagcaaca tcctgtggaa gccgtggctg     1620

cagccgtgct gcggacattt cccgttctgt tcatgccacg aggatgggga tggcaccccc     1680


<210>  5371
<211>  1674
<212>  DNA
<213>  Homo Sapiens

<400>  5371
gacatttccg cctcccgacc gaacatcctt cttctgatgg cggacgacct tggcattggg       60

gacgttggct gctatggcaa caacaccatg aggactccga atattgaccg ccttgcagag      120

gacggcgtga agctgaccca acacatctct gccgcatctt tgtgcacccc aagcagagcc      180

gccttcctca cgggcagata ccctgtgcga tcagggatgg tttccagcat tggttaccgt      240

gttcttcagt ggaccggagc atctggaggt cttccaacaa atgagacaac ttttgcaaaa      300

atactgaaag agaaaggcta tgccactgga ctcattggaa aatggcatct gggtctcaac      360

tgtgagtcag ccagtgatca ttgccaccac cctctccatc atggctttga ccatttctac      420

ggaatgcctt tctccttgat gggtgattgc gcccgctggg aactctcaga gaagcgtgtc      480

aacctggaac aaaaactcaa cttcctcttc caagtcctgg ccttggttgc cctcacactg      540

gtagcaggga agctcacaca cctgataccc gtctcgtgga tgccggtcat ctggtcagcc      600

ctttcggccg tcctcctcct cgcaagctcc tattttgtgg gtgctctgat tgtccatgcc      660

gattgctttc tgatgagaaa ccacaccatc acggagcagc ccatgtgctt ccaaagaacg      720

acacccctta ttctgcagga ggttgcgtcc tttctcaaaa ggaataagca tgggcctttc      780

ctcctctttg tttcctttct acacgttcac atccctctta tcactatgga gaacttcctc      840

gggaagagtc tccacgggct gtatggggac aacgtagagg agatggactg gatggtagga      900

cggatccttg acactttgga cgtggagggt ttgagcaaca gcaccctcat ttattttacg      960

tcggatcacg gcggttccct agagaatcaa cttggaaaca cccagtatgg tggctggaat     1020

ggaatttata aaggtgggaa gggcatggga ggatgggaag gtgggatccg cgtgcccggg     1080

atcttccgct ggcccggggt gctcccggcc ggccgagtga ttggcgagcc cacgagtctg     1140

atggacgtgt tccccaccgt ggtccggctg gcgggcggcg aggtgcccca ggacagagtg     1200

attgacggcc aagaccttct gcccttgctc ctggggacag cccaacactc agaccacgag     1260

ttcctgatgc attattgtga gaggtttctg cacgcagcca ggtggcatca acgggacaga     1320

ggaacaatgt ggaaagtcca ctttgtgacg cctgtgttcc agccagaggg agccggtgcc     1380

tgctatggaa gaaaggtctg cccgtgcttt ggggaaaaag tagtccacca cgatccacct     1440

ttgctctttg acctctcaag agacccttct gagacccaca tcctcacacc agcctcagag     1500

cccgtgttct atcaggtgat ggaacgagtc cagcaggcgg tgtgggaaca ccagcggaca     1560

ctcagcccag ttcctctgca gctggacagg ctgggcaaca tctggagacc gtggctgcag     1620

ccctgctgtg gcccgttccc cctctgctgg tgccttaggg aagatgaccc acaa           1674


<210>  5372
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  5372
agcctggccg gtgggagccc cggcgcggcc gaggccccgg ggtcggccca ggtggctgga       60

ctatgcgggc gcctaaccct tcaccgggac ctgcgcaccg gccgctggga accagaccca      120

cagcgctctc gacgctgtct ccgggacccg cagcgcgtgc tggagtactg cagacagatg      180

tacccggagc tgcagattgc acgtgtggag caggctacgc aggccatccc catggagcgc      240

tggtgcgggg gttcccggag cggcagctgc gcccaccccc accaccaggt tgtgcccttc      300

cgctgcctgc ctggtgaatt tgtgagtgag gccctgctgg tgcctgaagg ctgccggttc      360

ttgcaccagg agcgcatgga ccaatgtgag agttcaaccc ggaggcatca ggaggcacag      420

gaggcctgca gctcccaggg cctcatcctg cacggctcgg gcatgctctt accctgtggc      480

tcggatcggt tccgtggtgt ggagtatgtg tgctgtcccc ctccagggac ccccgaccca      540

tctgggacag cagttggtga cccctccacc cggtcctggc ccccggggag cagagtagag      600

ggggctgagg acgaggaaga ggaggaatcc ttcccacagc cagtagatga ttacttcgtg      660

gagcctccgc aggctgaaga ggaagaggaa acggtcccac ccccaagctc ccatacactt      720

gcagtggtcg gcaaagtcac tcccaccccg aggcccacag acggtgtgga tatttacttt      780

ggcatgcctg gggaaatcag tgagcacgag gggttcctga gggccaagat ggacctggag      840

gagcgtagga tgcgccagat taatgaggtg atgcgtgaat gggccatggc agacaaccag      900

tccaagaacc tgcctaaagc cgacagacag gccctgaatg agcacttcca gtccattctg      960

cagactctgg aggagcaggt gtctggtgag cgacagcgcc tggtggaaac ccacgccacc     1020

cgcgtcatcg cccttatcaa cgaccagcgc cgggctgcct tggagggctt cctggcagcc     1080

ctgcaggcag atccgcctca ggcggagcgt gtcctgttgg ccctgcggcg ctacctgcgt     1140

gcggagcaga aggaacagag gcacacgctg cgccactacc agcatgtggc cgccgtggat     1200

cccgagaagg cacagcagat gcgcttccag gtgcataccc accttcaagt gattgaggag     1260

agggtgaatc agagcctggg cctgcttgac cagaaccccc acctggctca ggagctgcgg     1320

ccccaaatcc aggaactcct ccactctgaa cacctgggtc ccagtgaatt ggaagcccct     1380

gcccctgggg gcagcagcga ggacaagggt gggctgcagc ctccagattc caaggatgac     1440

acccccatga cccttccaaa agggtccaca gaacaagatg ctgcatcccc tgagaaagag     1500

aagatgaacc cgctggaaca gtatgagcga aaggtgaatg cgtctgttcc aaggggtttc     1560

cctttccact catcggagat tcagagggat gagctggcac cagctgggac aggggtgtcc     1620

cgtgag                                                                1626


<210>  5373
<211>  153
<212>  DNA
<213>  Homo Sapiens

<400>  5373
tactttcagt caggcaacaa tgaagagcct tatgtcagta tcaccaagaa gaggcaaatg       60

ccaaaaaatg gcctctcaga ggagattgag aaggaggtgg gccaggcaga aggcaaacta      120

atcacccacc gatcagcgtt cagccgggcg tcg                                   153


<210>  5374
<211>  1251
<212>  DNA
<213>  Homo Sapiens

<400>  5374
ctcccctaca agataggggt ggtgggccct tgggcttgtg attcgctgtt ttcaaaggcc       60

ctgcctgagg ttgctgcgcg attagccatt gagcgaatca accgggaccc atcttttgac      120

ctgagttatt cttttgaata cgtgattctc aatgaagact gccagacttc gagggctctc      180

tccagtttca tttcccacca ccagatggcc tcaggattta ttggacctac caaccctggc      240

tactgcgagg cagcctcgct cctgggaaac agctgggaca aaggaatttt ctcttgggct      300

tgtgtgaatt atgaattaga caataaaatt agctacccga ccttttctcg gacactccct      360

tctcccatcc gggtgcttgt aactgtcatg aaatatttcc agtgggctca tgctggagtc      420

atttcctcag atgaagacat ttgggtgcat acagccaatc gagtcgcaag tgctcttcgg      480

agccacggct tacctgtagg ggtcgtcctg accacaggac aagacagcca aagcatgcgg      540

aaagccctcc agaggattca ccaggcagac agaattcgca taatcatcat gtgtatgcat      600

tcagctttga ttgggggaga gactcagatg catctcttgg aatgtgctca tgatctgaaa      660

atgactgatg gaacctacgt ctttgttcct tatgatgccc tgctctacag tttaccttat      720

aagcacaccc cctaccgggt cctaaggaac aacccaaagc tccgggaagc ctatgatgca      780

gtgttgacca ttacagtgga gtcccaagaa aagaccttct atcaagcctt cacagaggca      840

gcagcaagag gtgaaattcc tgagaagctg gagttcgatc aagtttcacc gttgtttgga      900

accatctaca attcaattta ctttatcgca caagccatga ataatgctat gaaagaaaat      960

ggacaggctg gtgctgccag cctggttcag cattccagaa acatgcagtt ccatggattc     1020

aaccagttga tgaggacaga ttcaaatgga aatggaattt cagaatatgt aatcctggac     1080

accaacttga aagaatggga actccatagc acctacactg tggacatgga aatggagctg     1140

ctacgtttcg gagggacccc tattcacttc cctggtggca ggccccctag agcagatgca     1200

aaatgctggt ttgcagaagg gaagatctgc catggaggca tcgaccctgc c              1251


<210>  5375
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  5375
gtggcggctc aaaactcagc tgaagtggtt cgttgcctca acagtgctct acaggtcggc       60

tgcggggctt ttgcatgcct ggaaaactcc acctgtgaca cagatgggat gtatgacatc      120

tgtaaatcct tcttgtacag cgctgctaaa tttgacactc agggaaaagc attcgtcaaa      180

gagagcttaa aatgcatcgc caacggggtc acctccaagg tcttcctcgc cattcggagg      240

tgctccactt tccaaaggat gattgctgag gtgcaggaag agtgctacag caagctgaat      300

gtgtgcagca tcgccaagcg gaaccctgaa gccatcactg aggtcgtcca gctgcccaat      360

cacttctcca acagatacta taacagactt gtccgaagcc tgctggaatg tgatgaagac      420

acagtcagca caatcagaga cagcctgatg gagaaaattg ggcctaacat ggccagcctc      480

ttccacatcc tgcagacaga ccactgtgcc caaacacacc cacgagctga cttcaacagg      540

agacgcacca atgagccgca gaagctgaaa gtcctcctca ggaacctccg aggtgaggag      600

gactctccct cccacatcaa acgcacatcc catgagagtg ca                         642


<210>  5376
<211>  819
<212>  DNA
<213>  Homo Sapiens

<400>  5376
cagagccacc ccatcacacg acgagacctc ttctctcaag agattcagct ggacatggcc       60

ctggcctcct ttgatgacca gtacgctggc tgtgctgctg ccatgacagc tgctctcccg      120

gatctcaacc acacggagtt ccaggccaac caggtgtatg cagacagctg gacactggca      180

agcagccaat ggcaggagcg tcaggccagg tggccagagt ggagtctcag ccccacccgt      240

ccatccccgc cacccctggg cttccgcgat gagcatgggg tggccctcct ggcctacaca      300

gccaacagcc ccctgcacaa ggagttcaat gcagccgtgc gtgaggcggg ccgctcccgg      360

gcccactacc tccaccactt ctccttcaag acactccatt tcctgctgac tgaggccctg      420

cagctcctgg gcagcggcca gcgtccaccc cggtgccacc aggtgttccg aggtgtgcac      480

ggcctgcgct tccggccagc agggccccgg gccaccgtga ggctgggggg ctttgcttct      540

gcctccctga agcatgttgc agcccagcag tttggtgagg acaccttctt cggcatctgg      600

acctgccttg gggcccctat caagggctac tccttcttcc ctggagagga agaggtgctg      660

atccccccct ttgagacctt ccaagtgatc aatgccagca gactggccca gggccccgcc      720

cgcatctacc tccgagccct gggcaagcac agcacctaca actgcgagta catcaaagac      780

aagaagtgca agtctgggcc ttgccatctg gataattca                             819


<210>  5377
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  5377
gacacacctg ccaactgcac ctatcttgac ctgctgggca cctgggtctt ccaggtgggc       60

tccagcggtt cccagcgcga tgtcaactgc tcggttatgg gaccacaaga aaaaaaagta      120

gtggtgtacc ttcagaagct ggatacagca tatgatgacc ttggcaattc tggccatttc      180

accatcattt acaaccaagg ctttgagatt gtgttgaatg actacaagtg gtttgccttt      240

tttaagtata aagaagaggg cagcaaggtg accacttact gcaacgagac aatgactggg      300

tgggtgcatg atgtgttggg ccggaactgg gcttgtttca ccggaaagaa ggtgggaact      360

gcctctgaga atgtgtatgt caacacagca caccttaaga attctcagga aaagtattct      420

aataggctct acaagtatga tcacaacttt gtgaaagcta tcaatgccat tcagaagtct      480

tggactgcaa ctacatacat ggaatatgag actcttaccc tgggagatat gattaggaga      540

agtggtggcc acagtcgaaa aatcccaagg cccaaacctg caccactgac tgctgaaata      600

cagcaaaaga ttttgcattt gccaacatct tgggactgga gaaatgttca tggtatcaat      660

tttgtcagtc ctgttcgaaa ccaagcatcc tgtggcagct gctactcatt tgcttctatg      720

ggtatgctag aagcgagaat ccgtatacta accaacaatt ctcagacccc aatcctaagc      780

cctcaggagg ttgtgtcttg tagccagtat gctcaaggct gtgaaggcgg cttcccatac      840

cttattgcag gaaagtacgc ccaagatttt gggctggtgg aagaagcttg cttcccctac      900

acaggcactg attctccatg caaaatgaag gaagactgct ttcgttatta ctcctctgag      960

taccactatg taggaggttt ctatggaggc tgcaatgaag ccctgatgaa gcttgagttg     1020

gtccatcatg ggcccatggc agttgctttt gaagtatatg atgacttcct ccactacaaa     1080

aaggggatct accaccacac tggtctaaga gaccctttca acccctttga gctgactaat     1140

catgctgttc tgcttgtggg ctatggcact gactcagcct ctgggatgga ttactggatt     1200

gttaaaaaca gctggggcac cggctggggt gagaatggct acttccggat ccgcagagga     1260

actgatgagt gtgcaattga gagcatagca gtggcagcca caccaattcc taaattg        1317


<210>  5378
<211>  192
<212>  DNA
<213>  Homo Sapiens

<400>  5378
caggagcctc ccggagctgc ttgttctcag aacacaaaca aaacctgtga agagtgcctg       60

aagaacgtct cctgtctttg gtgcaacact aacaaggctt gtctggacta cccagttaca      120

agcgtcttgc caccggcttc cctttgtaaa ttgagctctg cacgctgggg agtttgttgg      180

gtgaactttg ag                                                          192


<210>  5379
<211>  675
<212>  DNA
<213>  Homo Sapiens

<400>  5379
aatgaagata aggatcccgc ttttactgct ttgttaacca cccaaacaca agtgcaaagg       60

gagattgtga ataagcacaa tgaactgagg agagcagtat ctccccctgc cagaaacatg      120

ctgaagatgg aatggaacaa agaggctgca gcaaatgccc aaaagtgggc aaaccagtgc      180

aattacagac acagtaaccc aaaggatcga atgacaagtc taaaatgtgg tgagaatctc      240

tacatgtcaa gtgcctccag ctcatggtca caagcaatcc aaagctggtt tgatgagtac      300

aatgattttg actttggtgt agggccaaag actcccaacg cagtggttgg acattataca      360

caggttgttt ggtactcttc atacctcgtt ggatgtggaa atgcctactg tcccaatcaa      420

aaagttctaa aatactacta tgtttgccaa tattgtcctg ctggtaattg ggctaataga      480

ctatatgtcc cttatgaaca aggagcacct tgtgccagtt gcccagataa ctgtgacgat      540

ggactatgca ccaatggttg caagtacgaa gatctctata gtaactgtaa aagtttgaag      600

ctcacattaa cctgtaaaca tcagttggtc agggacagtt gcaaggcctc ctgcaattgt      660

tcaaacagca tttat                                                       675


<210>  5380
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  5380
aaagaggtct gctacggaca acttggctgc ttttctgatg aaaaaccatg ggcaggaacc       60

cttcagcgac ctgtaaaatt acttccctgg tcccccgagg acattgacac ccgctttctt      120

ctgtacacaa atgaaaatcc aaacaacttc caactaatca ctggcacgga accagacacc      180

attgaggctt caaacttcca actggaccgc aagacacgct tcatcatcca tggcttctta      240

gacaaggcgg aggacagctg gccatcggac atgtgcaaga aaatgtttga agtggagaag      300

gtgaactgca tctgtgtgga ctggaggcac gggtcccggg caatgtacac ccaagccgtg      360

caaaacattc gggttgttgg ggcggagaca gctttcttaa tacaagcact gtcgacgcag      420

ctggggtaca gccttgagga cgtgcatgtc atcggccaca gcctgggcgc gcacacggcc      480

gcggaggcgg gcaggaggct ggggggccgc gtgggcagga tcacagggct ggatccagca      540

gggccgtgct tccaggatga acctgaggag gttcggttgg atccatctga cgccgtgttt      600

gtggatgtga ttcacacaga ttcttctccc atagttcctt ccctaggttt cggaatgagc      660

caaaaggtgg gccatctgga tttctttcca aatggaggaa aggaaatgcc cggatgtaag      720

aaaaatgtcc tttcaaccat tactgatatt gatggaatat gggaaggaat tggtggcttt      780

gtgtcttgca atcacctaag aagcttcgag tattactcaa gcagcgtcct caaccctgat      840

ggcttcctgg gctatccctg tgcctcctac gatgagtttc aggagagtaa gtgtttccct      900

tgtccagctg aaggatgccc caaaatgggg cactatgctg accaatttaa ggggaaaaca      960

agtgctgtgg aacaaacctt tttcctgaac acaggagaga gtggtaactt tactagttgg     1020

agatataagg tatcagtcac actttctgga aaagagaaag tgaatgggta catcaggatt     1080

gctttgtatg gaagtaatga aaactcgaaa caatatgaga ttttcaaagg atccctcaaa     1140

ccagatgcaa gtcacacgtg tgctattgat gtggatttta atgttggaaa aatacagaaa     1200

gttaaattcc tctggaacaa acgtgggata aatctatctg agcccaaact gggggcttcc     1260

caaatcacag tgcaaagtgg tgaagatggg actgagtata atttttgtag cagcgacact     1320

gtggaagaaa acgtcttgca atctctttac ccttgt                               1356


<210>  5381
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5381
acgatgtggg ttatgcttca gactctcaac gatgaggttc caaaataccg tgaccagatt       60

cctagcccag gactcatggt ttttccaaaa ccagtgaccg cattggaata tacattcagt      120

aggtctgatc caacttcgta tgcagggtac attgaagacc ttaagaagtt tctaaaacca      180

tatactttag aagaacagaa gaacctcaca gtctgtcctg atggagcact ttttgaacag      240

aagggtccag tttatgttgc atgtcagttt cctatttcat tacttcaagc atgcagtggt      300

atgaatgatc ctgattttgg ctattctcaa ggaaaccctt gtattcttgt gaaaatgaac      360

agaataattg gattaaagcc tgaaggagtg ccaaggatag attgtgtttc aaagaatgaa      420

gatataccaa atgtagcagt ttatcctcat aatggaatga tagacttaaa atatttccca      480

tattatggga aaaaactgca tgttgggtat ctacagccat tggttgctgt tcaggtcagc      540

tttgctccta acaacactgg gaaagaagta acagttgagt gcaagattga tggatcagcc      600

aacctaaaaa gtcaggatga tcgtgacaag tttttgggac gagttatgtt caaaatcaca      660

gcacgtgca                                                              669


<210>  5382
<211>  1704
<212>  DNA
<213>  Homo Sapiens

<400>  5382
cacagggtgc atgacgacaa gcctaatatt gtcctaatca tggttgatga cctgggtatt       60

ggagatctgg gctgctacgg caatgacacc atgaggacgc ctcacatcga ccgccttgcc      120

agggaaggcg tgcgactgac tcagcacatc tctgccgcct ccctctgcag cccaagccgg      180

tccgcgttct tgacgggaag ataccccatc cgatcaggta tggtttctag tggtaataga      240

cgtgtcatcc aaaatcttgc agtccccgca ggcctccctc ttaatgagac aacacttgca      300

gccttgctaa agaagcaagg atacagcacg gggcttatag gcaaatggca ccaaggcttg      360

aactgcgact cccgaagtga ccagtgccac catccatata attatgggtt tgactactac      420

tatggcatgc cgttcactct cgttgacagc tgctggccgg acccctctcg taacacggaa      480

ttagcctttg agagtcagct ctggctctgt gtgcagctag ttgccattgc catcctcacc      540

ctaacctttg ggaagctgag cggctgggtc tctgttccct ggctcctgat cttctccatg      600

attctgttta ttttcctctt gggctatgct tggttctcca gccacacgtc ccctttatac      660

tgggactgcc tcctcatgcg ggggcacgag atcacggagc agcccatgaa ggctgaacga      720

gctggatcca ttatggtgaa ggaagcgatt tcctttttag aaaggcacag taaggaaact      780

ttccttctct ttttctcctt tcttcacgtg cacacacctc tccccaccac ggacgatttc      840

actggcacca gcaagcatgg cttgtatggg gataatgtgg aagagatgga ctccatggtg      900

ggcaagattc ttgatgctat cgatgatttt ggcctaagga acaacaccct tgtctacttt      960

acatcagatc acggagggca tttggaagct aggcgagggc atgcccaact tggtggatgg     1020

aatggaatat acaaaggtgg aaaaggcatg gggggctggg aaggtggaat ccgcgtccca     1080

ggaattgtcc gatggcctgg aaaggtacca gctggacggt tgattaagga acctacaagt     1140

ttaatggata ttttaccaac tgtcgcatca gtgtcaggag gaagtctccc tcaggacagg     1200

gtcattgacg gccgagacct catgcccttg ctgcagggca acgtcaggca ctcggagcat     1260

gaatttcttt tccactactg tggctcctac ctgcacgccg tgcggtggat ccccaaggac     1320

gacagtgggt cagtttggaa ggctcactat gtgaccccgg tattccagcc accagcttct     1380

ggtggctgct atgtcacctc attatgcaga tgtttcggag aacaggttac ctaccacaac     1440

ccccctctgc tcttcgatct ctccagggac ccctcagagt ccacacccct gacacctgcc     1500

acagagcccc tctatgattt tgtgattaaa aaggtggcca acgccctgaa ggaacaccag     1560

gaaaccatcg tgcctgtgac ctaccaactc tcagaactga atcagggcag gacgtggctg     1620

aagccttgct gtggggtgtt cccattttgt ctgtgtgaca aggaagagga agtctctcag     1680

cctcggggtc ctaacgagaa gaga                                            1704


<210>  5383
<211>  1929
<212>  DNA
<213>  Homo Sapiens

<400>  5383
tacgtgctcg acgactccga cgggctgggc cgggagttcg acggcatcgg cgcggtcagc       60

ggcggcgggg caacctcccg acttctagta aattacccag agccctatcg ttctcagata      120

ttggattatc tctttaagcc gaattttggt gcctctttgc atattttaaa agtggaaata      180

ggtggtgatg ggcagacaac agatggcact gagccctccc acatgcatta tgcactagat      240

gagaattatt tccgaggata cgagtggtgg ttgatgaaag aagctaagaa gaggaatccc      300

aatattacac tcattgggtt gccatggtca ttccctggat ggctgggaaa aggtttcgac      360

tggccttatg tcaatcttca gctgactgcc tattatgtcg tgacctggat tgtgggcgcc      420

aagcgttacc atgatttgga cattgattat attggaattt ggaatgagag gtcatataat      480

gccaattata ttaagatatt aagaaaaatg ctgaattatc aaggtctcca gcgagtgaaa      540

atcatagcaa gtgataatct ctgggagtcc atctctgcat ccatgctcct tgatgccgaa      600

ctcttcaagg tggttgatgt tataggggct cattatcctg gaacccattc agcaaaagat      660

gcaaagttga ctgggaagaa gctttggtct tctgaagact ttagcacttt aaatagtgac      720

atgggtgcag gctgctgggg tcgcatttta aatcagaatt atatcaatgg ctatatgact      780

tccacaatcg catggaattt agtggctagt tactatgaac agttgcctta tgggagatgc      840

gggttgatga cggcccagga gccatggagt gggcactacg tggtagaatc tcctgtctgg      900

gtatcagctc ataccactca gtttactcaa cctggctggt attacctgaa gacagttggc      960

catttagaga aaggaggaag ctacgtagct ctgactgatg gcttagggaa cctcaccatc     1020

atcattgaaa ccatgagtca taaacattct aagtgcatac ggccatttct tccttatttc     1080

aatgtgtcac aacaatttgc cacctttgtt cttaagggat cttttagtga aataccagag     1140

ctacaggtat ggtataccaa acttggaaaa acatccgaaa gatttctttt taagcagctg     1200

gattctctat ggctccttga cagcgatggc agtttcacac tgagcctgca tgaagatgag     1260

ctgttcacac tcaccactct caccactggt cgcaaaggca gctacccgct tcctccaaaa     1320

tcccagccct tcccaagtac ctataaggat gatttcaatg ttgattaccc attttttagt     1380

gaagctccaa actttgctga tcaaactggt gtatttgaat attttacaaa tattgaagac     1440

cctggcgagc atcacttcac gctacgccaa gttctcaacc agagacccat tacgtgggct     1500

gccgatgcat ccaacacaat cagtattata ggagactaca actggaccaa tctgactaca     1560

aagtgtgatg tttacataga gacccctgac acaggaggtg tgttcattgc aggaagagta     1620

aataaaggtg gtattttgat tagaagtgcc agaggaattt tcttctggat ttttgcaaat     1680

ggatcttaca gggttacagg tgatttagct ggatggatta tatatgcttt aggacgtgtt     1740

gaagttacag caaaaaaatg gtatacactc acgttaacta ttaagggtca tttcgcctct     1800

ggcatgctga atgacaagtc tctgtggaca gacatccctg tgaattttcc aaagaatggc     1860

tgggctgcaa ttggaactca ctcctttgaa tttgcacagt ttgacaactt tcttgtggaa     1920

gccacacgc                                                             1929


<210>  5384
<211>  1413
<212>  DNA
<213>  Homo Sapiens

<400>  5384
ggaaaggtgc tggtgtggcc cacagaatac agccattgga taaatatgaa gacaatcctg       60

gaagagcttg ttcagagggg tcatgaggtg attgtgttga catcttcggc ttctattctt      120

gtcaatgcca gtaaatcatc tgctattaaa ttagaagttt atcctacatc tttaactaaa      180

aatgatttgg aagatttttt tatgaaaatg ttcgatagat ggacatatag tatttcaaaa      240

aatacatttt ggtcatattt ttcacaacta caagaattgt gttgggaata ttctgactat      300

aatataaagc tctgtgaaga tgcagttttg aacaagaaac ttatgagaaa actacaagag      360

tcaaaatttg atgtccttct ggcagatgcc gttaatccct gtggtgagct gctggctgaa      420

ctacttaaca taccctttct gtacagtctc cgcttctctg ttggctacac agttgagaag      480

aatggtggag gatttctgtt ccctccttcc tatgtacctg ttgttatgtc agaattaagt      540

gatcaaatga ttttcatgga gaggataaaa aatatgatat atatgcttta ttttgacttt      600

tggtttcaag catatgatct gaagaagtgg gaccagtttt atagtgaagt tctaggaaga      660

cccactacat tatttgagac aatggggaaa gctgaaatgt ggctcattcg aacctattgg      720

gattttgaat ttcctcgccc attcttacca aatgttgatt ttgttggagg acttcactgt      780

aaaccagcca aacccttgcc taaggaaatg gaagagtttg tgcagagctc tggagaaaat      840

ggtattgtgg tgttttctct ggggtcgatg atcagtaaca tgtcagaaga aagtgccaac      900

atgattgcat cagcccttgc ccagatccca caaaaggttc tatggagatt tgatggcaag      960

aagccaaata ctttaggttc caatactcga ctgtataagt ggttacccca gaatgacctt     1020

cttggtcatc ccaaaaccaa agcttttata actcatggtg gaaccaatgg catctatgag     1080

gcgatctacc atgggatccc tatggtgggc attcccttgt ttgcggatca acatgataac     1140

attgctcaca tgaaagccaa gggagcagcc ctcagtgtgg acatcaggac catgtcaagt     1200

agagatttgc tcaatgcatt gaagtcagtc attaatgacc ctatctataa agagaatatc     1260

atgaaattat caagaattca tcatgatcaa ccggtgaagc ccctggatcg agcagtcttc     1320

tggattgagt ttgtcatgcg ccataaagga gccaagcacc ttcgggtcgc agcccacaac     1380

ctcacctgga tccagtacca ctctttggat gtg                                  1413


<210>  5385
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  5385
cagggccagt atgacctgga cccgctgccg ccgttccctg accacgtcca gtacacccac       60

tatagcgacc agatcgacaa cccagactac tatgattatc aagaggtgac tcctcggccc      120

tccgaggaac agttccagtt ccagtcccag cagcaagtcc aacaggaagt catcccagcc      180

ccaaccccag aaccaggaaa tgcagagctg gagcccacag agcctgggcc tcttgactgc      240

cgtgaggaac agtacccgtg cacccgcctc tactccatac acaggccttg caaacagtgt      300

ctcaacgagg tctgcttcta cagcctccgc cgtgtgtacg tcattaacaa ggagatctgt      360

gttcgtacag tgtgtgccca cgaggagctc ctccgagctg acctctgtcg ggacaagttc      420

tccaaatgtg gcgtgatggc cagcagcggc ctgtgccaat ccgtggcggc ctcctgtgcc      480

aggagctgtg ggagctgc                                                    498


<210>  5386
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  5386
gaggcccagg aaggaaccct gagcccccca ccaaagctaa agatgagtcg ctggagcctg       60

gtgaggggca ggatgaagga gctgctggag acagtggtga acaggaccag agacgggtgg      120

caatggttct ggagcccgag caccttccgg ggcttcatgc agacctacta tgacgaccac      180

ctgagggacc tgggtccgct caccaaggcc tggttcctcg aatccaaaga cagcctcttg      240

aagaagaccc acagcctgtg ccccaggctt gtctgtgggg acaaggacca gggt            294


<210>  5387
<211>  1428
<212>  DNA
<213>  Homo Sapiens

<400>  5387
gagttcccag gctgcaagat ccgcgtcacc tccaaggcgc tggagctggt gaagcaggag       60

gggctgcgct ttctggagca agagctggag actatcacca ttccggacct gcggggcaaa      120

gaaggccact tctactacaa catctctgag gtgaaggtca cagagctgca actgacatct      180

tccgagctcg atttccagcc acagcaggag ctgatgcttc aaatcaccaa tgcctccttg      240

gggctgcgct tccggagaca gctgctctac tggttcttct atgatggggg ctacatcaac      300

gcctcagctg agggtgtgtc catccgcact ggtctggagc tctcccggga tcccgctgga      360

cggatgaaag tgtccaatgt ctcctgccag gcctctgtct ccagaatgca cgcggccttc      420

gggggaacct tcaagaaggt gtatgatttt ctctccacgt tcatcacctc agggatgcgc      480

ttcctcctca accagcagat ctgccctgtc ctctaccacg cagggacggt cctgctcaac      540

tccctcctgg acaccgtgcc tgtgcgcagt tctgtggacg agcttgttgg cattgactat      600

tccctcatga aggatcctgt ggcttccacc agcaacctgg acatggactt ccggggggcc      660

ttcttccccc tgactgagag gaactggagc ctccccaacc gggcagtgga gccccagctg      720

caggaggaag agcggatggt gtatgtggcc ttctctgagt tcttcttcga ctctgccatg      780

gagagctact tccgggcggg ggccctgcag ctgttgctgg tgggggacaa ggtgccccac      840

gacctggaca tgctgctgag ggccacctac tttgggagca ttgtcctgct gagcccagca      900

gtgattgact ccccattgaa gctggagctg cgggtcctgg ccccaccgcg ctgcaccatc      960

aagccctctg gcaccaccat ctctgtcact gctagcgtca ccattgccct ggtcccacca     1020

gaccagcctg aggtccagct gtccagcatg actatggacg cccgtctcag cgccaagatg     1080

gctctccggg ggaaggccct gcgcacgcag ctggacctgc gcaggttccg aatctattcc     1140

aaccattctg cactggagtc gctggctctg atcccattac aggcccctct gaagaccatg     1200

ctgcagattg gggtgatgcc catgctcaat gagcggacct ggcgtggggt gcagatccca     1260

ctacctgagg gcatcaactt tgtgcatgag gtggtgacga accatgcggg attcctcacc     1320

atcggggctg atctccactt tgccaaaggg ctgcgagagg tgattgagaa gaaccggcct     1380

gctgatgtca gggcgtccac tgcccccaca ccgtccacag cagctgtc                  1428


<210>  5388
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5388
gtctccggga tccgaggaga tgctctggag aggttttgcc ttcagcaacc cctggactgt       60

gacgacatct atgcccaggg ctaccagtca gacggcgtgt acctcatcta cccctcgggc      120

cccagtgtgc ctgtgcccgt cttctgtgac atgaccaccg agggcgggaa gtggacggtt      180

ttccagaaga gattcaatgg ctcagtaagt ttcttccgcg gctggaatga ctacaagctg      240

ggcttcggcc gtgctgatgg agagtactgg ctggggctgc agaacatgca cctcctgaca      300

ctgaagcaga agtatgagct gcgagtggac ttggaggact ttgagaacaa cacggcctat      360

gccaagtacg ctgacttctc catctccccg aacgcggtca gcgcagagga ggatggctac      420

accctctttg tggcaggctt tgaggatggc ggggtaggtg actccctgtc ctaccacagt      480

ggccagaagt tctctacctt cgaccgggac caggacctct ttgtgcagaa ctgcgcagct      540

ctctcctcag gagccttctg gttccgcagc tgccactttg ccaacctcaa tggcttctac      600

ctaggtggct cccacctctc ttatgccaat ggcatcaact gggcccagtg gaagggcttc      660

tactactccc tcaaacgcac tgagatgaaa atccgccggg cc                         702


<210>  5389
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  5389
ggcatcgact gccaaggagg gtccaggatg tgctgtcgac aagagttttt tgtggacttc       60

cgtgagattg gctggcacga ctggatcatc cagcctgagg gctacgccat gaacttctgc      120

atagggcagt gcccactaca catagcaggc atgcctggta ttgctgcctc ctttcacact      180

gcagtgctca atcttctcaa ggccaacaca gctgcaggca ccactggagg gggctcatgc      240

tgtgtaccca cggcccggcg ccccctgtct ctgctctatt atgacaggga cagcaacatt      300

gtcaagactg acatacctga catggtagta gaggcctgtg ggtgcagt                   348


<210>  5390
<211>  474
<212>  DNA
<213>  Homo Sapiens

<400>  5390
ctgcggccgg gcgactgcga agtttgtatt tcttatctgg gaagatttta ccaggacctc       60

aaagacagag atgtcacatt ctcaccagcc actattgaaa acgaacttat aaagttctgc      120

cgggaagcaa gaggcaaaga gaatcggttg tgctactata tcggggccac agatgatgca      180

gccaccaaaa tcatcaatga ggtatcaaag cctctggccc accacatccc tgtggagaag      240

atctgtgaga agcttaagaa gaaggacagc cagatatgtg agcttaagta tgacaagcag      300

atcgacctga gcacagtgga cctgaagaag ctccgagtta aagagctgaa gaagattctg      360

gatgactggg gggagacatg caaaggctgt gcagaaaagt ctgactacat ccggaagata      420

aatgaactga tgcctaaata tgcccccaag gcagccagtg cacggaccga tttg            474


<210>  5391
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  5391
caaagagact ttgatttggc agatgccctt gatgaccctg aacccaccaa gaagccaaac       60

tcagatatct acccaaagcc aaaaccacct tactacccac agcccgagaa tcccgacagc      120

ggtggaaata tctacccaag gccaaagcca cgccctcaac cccagcctgg caattccggc      180

aacagtggag gttacttcaa tgatgtggac cgtgatgacg gacgctaccc gcccaggccc      240

aggccacggc cgcctgcagg aggtggcggc ggtggctact ccagttatgg caactccgac      300

aacacgcacg gaagaggggg ctatagaccc aactctcgtt atggaaatac ttatggtgga      360

gatcaccatt caacgtatgg caatccagaa ggcaatatgg tagcaaaa                   408


<210>  5392
<211>  837
<212>  DNA
<213>  Homo Sapiens

<400>  5392
ttgcacgaga aggcttacca ggtacgggac acagccattg agtcctcggt ggtaaccaag       60

gtgaagggct ccggactcta cgccaacaga gtcatggatg tgtctgatta cgtgacgcca      120

cctcagggca cctcggtctt tgtcatcatc accaagatga ttgttactga aaatcagatg      180

caaggattct gcccagagag tgaggagaaa taccgctgtg tatcagacag ccagtgcggg      240

cctgagcgct tgccaggtgg ggggatcctc actggccgct gcgtgaacta cagctctgtg      300

ctccggacct gtgagatcca gggctggtgc cccacggagg tggacacagt ggaaacgccc      360

atcatgatgg aagctgagaa cttcactatt ttcatcaaga acagcatccg tttccccctc      420

ttcaactttg agaagggaaa cctccttccc aacctgacag ccagggacat gaagacctgc      480

cgcttccacc cggacaagga ccctttctgc cccatcttgc gggtagggga cgtggtcaag      540

tttgcggggc aggattttgc caaactggcg cgcacggggg gagttctggg cattaagatc      600

ggctgggtgt gcgacttgga caaggcctgg gaccagtgca tccccaaata ctccttcacc      660

cggctcgaca gcgtttctga gaaaagcagc gtgtccccag gctacaactt caggtttgcc      720

aagtactaca aaatggaaaa tggcagtgag taccgcaccc tcctgaaggc ttttggcatc      780

cgcttcgacg tgctggtata cgggaatgct ggcaagttca acatcatccc caccatc         837


<210>  5393
<211>  1002
<212>  DNA
<213>  Homo Sapiens

<400>  5393
agctacccga tctggtggtc gctggctgtt gggccacagt attcctccct gggctcgcag       60

cccatcctgt gtgccagcat cccgggcctg gtccccaagc agctccgctt ctgcaggaac      120

tacgtggaga tcatgcccag cgtggccgag ggcatcaaga ttggcatcca ggagtgccag      180

caccagttcc gcggccgccg gtggaactgc accaccgtcc acgacagcct ggccatcttc      240

gggcccgtgc tggacaaagc taccagggag tcggcctttg tccacgccat tgcctcagcc      300

ggtgtggcct ttgcagtgac acgctcatgt gcagaaggca cggccgccat ctgtggctgc      360

agcagccgcc accagggctc accaggcaag ggctggaagt ggggtggctg tagcgaggac      420

atcgagtttg gtgggatggt gtctcgggag ttcgccgacg cccgggagaa ccggccagat      480

gcccgctcag ccatgaaccg ccacaacaac gaggctgggc gccaggccat cgccagccac      540

atgcacctca agtgcaagtg ccacgggctg tcgggcagct gcgaggtgaa gacatgctgg      600

tggtcgcaac ccgacttccg cgccatcggt gacttcctca aggacaagta cgacagcgcc      660

tcggagatgg tggtggagaa gcaccgggag tcccgcggct gggtggagac cctgcggccg      720

cgctacacct acttcaaggt gcccacggag cgcgacctgg tctactacga ggcctcgccc      780

aacttctgcg agcccaaccc tgagacgggc tccttcggca cgcgcgaccg cacctgcaac      840

gtcagctcgc acggcatcga cggctgcgac ctgctgtgct gcggccgcgg ccacaacgcg      900

cgagcggagc ggcgccggga gaagtgccgc tgcgtgttcc actggtgctg ctacgtcagc      960

tgccaggagt gcacgcgcgt ctacgacgtg cacacctgca ag                        1002


<210>  5394
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  5394
agcaactggc tgtacctggc caagctgtcg tcggtgggga gcatctcaga ggaggagacg       60

tgcgagaaac tcaagggcct gatccagagg caggtgcaga tgtgcaagcg gaacctggaa      120

gtcatggact cggtgcgccg cggtgcccag ctggccattg aggagtgcca gtaccagttc      180

cggaaccggc gctggaactg ctccacactc gactccttgc ccgtcttcgg caaggtggtg      240

acgcaaggga ctcgggaggc ggccttcgtg tacgccatct cttcggcagg tgtggccttt      300

gcagtgacgc gggcgtgcag cagtggggag ctggagaagt gcggctgtga caggacagtg      360

catggggtca gcccacaggg cttccagtgg tcaggatgct ctgacaacat cgcctacggt      420

gtggctttct cacagtcgtt tgtggatgtg cgggagagaa gcaagggggc ctcgtccagc      480

agagccctca tgaacctcca caacaatgag gccggcagga aggccatcct gacacacatg      540

cgggtggaat gcaagtgcca cggggtgtca ggctcctgtg aggtaaagac gtgctggcga      600

gccgtgccgc ccttccgcca ggtgggtcac gcactgaagg agaagtttga tggtgccact      660

gaggtggagc cacgccgcgt gggctcctcc agggcactgg tgccacgcaa cgcacagttc      720

aagccgcaca cagatgagga cctggtgtac ttggagccta gccccgactt ctgtgagcag      780

gacatgcgca gcggcgtgct gggcacgagg ggccgcacat gcaacaagac gtccaaggcc      840

atcgacggct gtgagctgct gtgctgtggc cgcggcttcc acacggcgca ggtggagctg      900

gctgaacgct gcagctgcaa attccactgg tgctgcttcg tcaagtgccg gcagtgccag      960

cggctcgtgg agttgcacac gtgccga                                          987


<210>  5395
<211>  975
<212>  DNA
<213>  Homo Sapiens

<400>  5395
gcactgtcat ccgtggtggc cctgggagcc aacatcatct gcaacaagat tcctggccta       60

gccccgcggc agcgtgccat ctgccagagt cggcccgatg ccatcattgt gattggggag      120

ggggcgcaga tgggcatcaa cgagtgccag taccagttcc gcttcggacg ctggaactgc      180

tctgccctcg gcgagaagac cgtcttcggg caagagctcc gagtagggag ccgtgaggct      240

gccttcacgt acgccatcac cgcggctggc gtggcgcacg ccgtcaccgc tgcctgcagc      300

caagggaacc tgagcaactg cggctgcgac cgcgagaagc agggctacta caaccaagcc      360

gagggctgga agtggggcgg ctgctcggcc gacgtgcgtt acggcatcga cttctcccgg      420

cgcttcgtgg acgctcggga gatcaagaag aacgcgcggc gcctcatgaa cctgcataac      480

aatgaggccg gcaggaaggt tctagaggac cggatgcagc tggagtgcaa gtgccacggc      540

gtgtctggct cctgcaccac caaaacctgc tggaccacgc tgcccaagtt ccgagaggtg      600

ggccacctgc tgaaggagaa gtacaacgcg gccgtgcagg tggaggtggt gcgggccagc      660

cgtctgcggc agcccacctt cctgcgcatc aaacagctgc gcagctatca gaagcccatg      720

gagacagacc tggtgtacat tgagaagtcg cccaactact gcgaggagga cgcggccacg      780

ggcagcgtgg gcacgcaggg ccgtctctgc aaccgcacgt cgcccggcgc ggacggctgt      840

gacaccatgt gctgcggccg aggctacaac acccaccagt acaccaaggt gtggcagtgc      900

aactgcaaat tccactggtg ctgcttcgtc aagtgcaaca cctgcagcga gcgcaccgag      960

gtcttcacct gcaag                                                       975


<210>  5396
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5396
cagtggagag tgtcggcctt cattgaaaac aacatcgtgg tttttgaaaa cttctgggaa       60

ggactgtgga tgaattgcgt gaggcaggct aacatcagga tgcagtgcaa aatctatgat      120

tccctgctgg ctctttctcc ggacctacag gcagccaga                             159


<210>  5397
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  5397
aactggagaa aattacgatt gatcacattc aacagaaacg agaagaacct gactgtttac       60

acaggcctgt gggtgaaatg tgcccggtat gacgggagca gtgactgcct gatgtacgac      120

actacttggt actcatcagt tgaccagctg gacctgcgtg tcctccag                   168


<210>  5398
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5398
cagtggagag tatcagcttt tgttggcagc aacattattg tctttgagag gctctgggaa       60

gggctctgga tgaattgcat ccgacaagcc agggtccggt tgcaatgcaa gttctatagc      120

tccttgttgg ctctcccgcc tgccctggaa acagcccgg                             159


<210>  5399
<211>  1308
<212>  DNA
<213>  Homo Sapiens

<400>  5399
acccagcacg gcatccggct gcccctgcgc agcggcctgg ggggcgcccc cctggggctg       60

cggctgcccc gggagaccga cgaagagccc gaggagcccg gccggagggg cagctttgtg      120

gagatggtgg acaacctgag gggcaagtcg gggcagggct actacgtgga gatgaccgtg      180

ggcagccccc cgcagacgct caacatcctg gtggatacag gcagcagtaa ctttgcagtg      240

ggtgctgccc cccacccctt cctgcatcgc tactaccaga ggcagctgtt cagcacatac      300

cgggacctcc ggaagggtgt gtatgtgccc tacacccagg gcaagtggga aggggagctg      360

ggcaccgacc tggtaagcat cccccatggc cccaacgtca ctgtgcgtgc caacattgct      420

gccatcactg aatcagacaa gttcttcatc aacggctcca actgggaagg catcctgggg      480

ctggcctatg ctgagattgc caggcctgac gactccctgg agcctttctt tgactctctg      540

gtaaagcaga cccacgttcc caacctcttc tccctgcagc tttgtggtgc tggcttcccc      600

ctcaaccagt ctgaagtgct ggcctctgtc ggagggagca tgatcattgg aggtatcgac      660

cactcgctgt acacaggcag tctctggtat acacccatcc ggcgggagtg gtattatgag      720

gtgatcattg tgcgggtgga gatcaatgga caggatctga aaatggactg caaggagtac      780

aactatgaca agagcattgt ggacagtggc accaccaacc ttcgtttgcc caagaaagtg      840

tttgaagctg cagtcaaatc catcaaggca gcctcctcca cggagaagtt ccctgatggt      900

ttctggctag gagagcagct ggtgtgctgg caagcaggca ccaccccttg gaacattttc      960

ccagtcatct cactctacct aatgggtgag gttaccaacc agtccttccg catcaccatc     1020

cttccgcagc aatacctgcg gccagtggaa gatgtggcca cgtcccaaga cgactgttac     1080

aagtttgcca tctcacagtc atccacgggc actgttatgg gagctgttat catggagggc     1140

ttctacgttg tctttgatcg ggcccgaaaa cgaattggct ttgctgtcag cgcttgccat     1200

gtgcacgatg agttcaggac ggcagcggtg gaaggccctt ttgtcacctt ggacatggaa     1260

gactgtggct acaacattcc acagacagat gagtcaaccc tcatgacc                  1308


<210>  5400
<211>  366
<212>  DNA
<213>  Homo Sapiens

<400>  5400
aaagaagttt cttggagaga attcatgaaa cagcactact taagtccaag tcgagaattc       60

agagagtaca aatgtgatgt cctcatgaga gaaaatgaag ctctgaaaga caagagctct      120

cacatgttta tctatatctc atggtacaaa atcgagcata tatgcactag tgacaactgg      180

atggatcgct tccgaaatgc atatgtatgg gtccagaatc ctctcaaagt actcaagtgt      240

caccaggaga attccaaaaa tagctacaca gagagcagga gcttcaacta cattgaattc      300

cattgtagca tggacgggta tgttgatagc atagaagacc taaagatggt agaacctatc      360

ggcaac                                                                 366


<210>  5401
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5401
gacatgtgga gcacccagga cctgtacgac aaccccgtca cctccgtgtt ccagtacgaa       60

gggctctgga ggagctgcgt gaggcagagt tcaggcttca ccgaatgcag gccctatttc      120

accatcctgg gacttccagc catgctgcag gcagtgcga                             159


<210>  5402
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5402
aactggaagg tgaatgtgga tgtggactcc aacatcataa cagccattgt acagctgcac       60

gggctctgga tggactgtac gtggtacagc actgggatgt tcagctgtgc cctgaaacac      120

tccattctgt ccctccccat ccacgtgcag gctgcgaga                             159


<210>  5403
<211>  687
<212>  DNA
<213>  Homo Sapiens

<400>  5403
atgcgaaagg tggttttgat caccggggct agcagtggca ttggcctggc cctctgcaag       60

cggctgctgg cggaagatga tgagcttcat ctgtgtttgg cgtgcaggaa catgagcaag      120

gcagaagctg tctgtgctgc tctgctggcc tctcacccca ctgctgaggt caccattgtc      180

caggtggatg tcagcaacct gcagtcggtc ttccgggcct ccaaggaact taagcaaagg      240

tttcagagat tagactgtat atatctaaat gctgggatca tgcctaatcc acaactaaat      300

atcaaagcac ttttctttgg cctcttttca agaaaagtga ttcatatgtt ctccacagct      360

gaaggcctgc tgacccaggg tgataagatc actgctgatg gacttcagga ggtgtttgag      420

accaatgtct ttggccattt tatcctgatt cgggaactgg agcctctcct ctgtcacagt      480

gacaatccat ctcagctcat ctggacatca tctcgcagtg caaggaaatc taatttcagc      540

ctcgaggact tccagcacag caaaggcaag gaaccctaca gctcttccaa atatgccact      600

gaccttttga gtgtggcttt gaacaggaac ttcaaccagc agggtctcta ttccaatgtg      660

gcctgtccag gtacagcatt gaccaat                                          687


<210>  5404
<211>  1152
<212>  DNA
<213>  Homo Sapiens

<400>  5404
cacttcgact gctcagggaa gtacagatgt cgctcatcct ttaagtgtat cgagctgata       60

gctcgatgtg acggagtctc ggattgcaaa gacggggagg acgagtaccg ctgtgtccgg      120

gtgggtggtc agaatgccgt gctccaggtg ttcacagctg cttcgtggaa gaccatgtgc      180

tccgatgact ggaagggtca ctacgcaaat gttgcctgtg cccaactggg tttcccaagc      240

tatgtaagtt cagataacct cagagtgagc tcgctggagg ggcagttccg ggaggagttt      300

gtgtccatcg atcacctctt gccagatgac aaggtgactg cattacacca ctcagtatat      360

gtgagggagg gatgtgcctc tggccacgtg gttaccttgc agtgcacagc ctgtggtcat      420

agaaggggct acagctcacg catcgtgggt ggaaacatgt ccttgctctc gcagtggccc      480

tggcaggcca gccttcagtt ccagggctac cacctgtgcg ggggctctgt catcacgccc      540

ctgtggatca tcactgctgc acactgtgtt tatgacttgt acctccccaa gtcatggacc      600

atccaggtgg gtctagtttc cctgttggac aatccagccc catcccactt ggtggagaag      660

attgtctacc acagcaagta caagccaaag aggctgggca atgacatcgc ccttatgaag      720

ctggccgggc cactcacgtt caatgaaatg atccagcctg tgtgcctgcc caactctgaa      780

gagaacttcc ccgatggaaa agtgtgctgg acgtcaggat ggggggccac agaggatgga      840

ggtgacgcct cccctgtcct gaaccacgcg gccgtccctt tgatttccaa caagatctgc      900

aaccacaggg acgtgtacgg tggcatcatc tccccctcca tgctctgcgc gggctacctg      960

acgggtggcg tggacagctg ccagggggac agcggggggc ccctggtgtg tcaagagagg     1020

aggctgtgga agttagtggg agcgaccagc tttggcatcg gctgcgcaga ggtgaacaag     1080

cctggggtgt acacccgtgt cacctccttc ctggactgga tccacgagca gatggagaga     1140

gacctaaaaa cc                                                         1152


<210>  5405
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5405
agctggaaaa caagttctta tgtcggtgcc agcattgtga cagcagttgg cttctccaag       60

ggcctctgga tggaatgtgc cacacacagc acaggcatca cccagtgtga catctatagc      120

acccttctgg gcctgcccgc tgacatccag gctgcccag                             159


<210>  5406
<211>  198
<212>  DNA
<213>  Homo Sapiens

<400>  5406
tcagaagctg ctagtctgtc tccaaaaaaa gtggactgca gcatttacaa gaagtatcca       60

gtggtggcca tcccctgccc catcacatac ctaccagttt gtggttctga ctacatcacc      120

tatgggaatg aatgtcactt gtgtaccgag agcttgaaaa gtaatggaag agttcagttt      180

cttcacgatg gaagttgc                                                    198


<210>  5407
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  5407
acccccacct gtgagcctgc gaccccctta tgttgcaggc gagaccatta cgtagacttc       60

caggaactgg gatggcggga ctggatactg cagcccgagg ggtaccagct gaattactgc      120

agtgggcagt gccctcccca cctggctggc agcccaggca ttgctgcctc tttccattct      180

gccgtcttca gcctcctcaa agccaacaat ccttggcctg ccagtacctc ctgttgtgtc      240

cctactgccc gaaggcccct ctctctcctc tacctggatc ataatggcaa tgtggtcaag      300

acggatgtgc cagatatggt ggtggaggcc tgtggctgca gc                         342


<210>  5408
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  5408
gctgtgatca caggggcctg tgagcgggat gtccagtgtg gggcaggcac ctgctgtgcc       60

atcagcctgt ggcttcgagg gctgcggatg tgcaccccgc tggggcggga aggcgaggag      120

tgccaccccg gcagccacaa gatccccttc ttcaggaaac gcaagcacca cacctgtcct      180

tgcttgccca acctgctgtg ctccaggttc ccggacggca ggtaccgctg ctccatggac      240

ttgaagaaca tcaatttt                                                    258


<210>  5409
<211>  750
<212>  DNA
<213>  Homo Sapiens

<400>  5409
gccaatttaa cgaacggtgg aaagtcagaa cttctgaaat caggaagcag caaatccaca       60

ctaaagcaca tatggacaga aagcagcaaa gacttgtcta tcagccgact cctgtcacag      120

acttttcgtg gcaaagagaa tgatacagat ttggacctga gatatgacac cccagaacct      180

tattctgagc aagacctctg ggactggctg aggaactcca cagaccttca agagcctcgg      240

cccagggcca agagaaggcc cattgttaaa acgggcaagt ttaagaaaat gtttggatgg      300

ggcgattttc attccaacat caaaacagtg aagctgaacc tgttgataac tgggaaaatt      360

gtagatcatg gcaatgggac atttagtgtt tatttcaggc ataattcaac tggtcaaggg      420

aatgtatctg tcagcttggt accccctaca aaaatcgtgg aatttgactt ggcacaacaa      480

accgtgattg atgccaaaga ttccaagtct tttaattgtc gcattgaata tgaaaaggtt      540

gacaaggcta ccaagaacac actctgcaac tatgaccctt caaaaacctg ttaccaggag      600

caaacccaaa gtcatgtatc ctggctctgc tccaagccct ttaaggtgat ctgtatttac      660

atttcctttt atagtacaga ttataaactg gtacagaaag tgtgccctga ctacaactac      720

cacagtgaca caccttactt tccctcggga                                       750


<210>  5410
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  5410
gagctcattc cagatgcacc cctgtccagt gctgcctata gcatccgcag catcggggag       60

aggcctgtcc tcaaagctcc agtccccaaa aggcaaaaat gtgaccactg gactccctgc      120

ccatctgaca cctatgccta caggttactc agcggaggtg gcagaagcaa gtacgccaaa      180

atctgctttg aggataacct acttatggga gaacagctgg gaaatgttgc cagaggaata      240

aacattgcca ttgtcaacta tgtaactggg aatgtgacag caacacgatg ttttgatatg      300

tatgaaggcg ataactctgg accgatgaca aagtttattc agagtgctgc tccaaaatcc      360

ctgctcttca tggtgaccta tgacgacgga agcacaagac tgaataacga tgccaagaat      420

gccatagaag cacttggaag taaagaaatc aggaacatga aattcaggtc tagctgggta      480

tttattgcag caaaaggctt ggaactccct tccgaaattc agagagaaaa gatcaaccac      540

tctgatgcta agaacaacag atattctggc tggcctgcag agatccagat agaaggctgc      600

atacccaaag aacgaagc                                                    618


<210>  5411
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  5411
ctcaccgact tctctggtta cctaaccaaa ctcctgcaaa accacaccac ctatgcctgt       60

gatggggact atttgaatct acagtgccct cggcattcta cgataagtgt ccaatcggca      120

ttttatgggc aagattacca aatgtgtagt tcccagaagc ctgcctccca gagggaagac      180

agcttaacct gtgtggcagc caccaccttc cagaaggtgc tggacgaatg ccagaaccag      240

cgggcctgcc acctcctggt caatagccgt gtttttggac ctgacctttg tccaggaagc      300

agtaaatacc tcctggtctc ctttaaatgc caacctaatg aattaaaaaa caaaaccgtg      360

tgtgaagacc aggagctgaa actgcactgc catgaatcca agttcctcaa catctactct      420

gcgacctacg gcaggaggac ccaggaaagg gacatctgct cctccaaggc agagcggctc      480

ccccctttcg attgcttgtc ttactcagct ttgcaagtcc tatcccgaag gtgctatggg      540

aagcagagat gcaaaatcat cgtcaacaat caccattttg gaagcccctg tttgccaggc      600

gtgaaaaaat acctcactgt gacctacgca tgtgttccca agaacatact cacagcgatt      660

gatccagcca ttgctaatct aaaaccttct ttgaagcaga aagatggtat aaacttcgac      720

ccaagcggat cgaaggttct gaggaaagat ggaattcttg ttagcaactc tctggcagcc      780

tttgcttaca ttagagccca cccggagaga gct                                   813


<210>  5412
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  5412
gacatcccag aagtggttgt ttcccttgca tgggacgaaa gcttggctcc aaagcatcca       60

ggctcaagga aaaacatggc ctgctattgc agaataccag cgtgcattgc aggagaacgt      120

cgctatggaa cctgcatcta ccagggaaga ctctgggcat tctgctgc                   168


<210>  5413
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  5413
tgccaggagc tgctagagac ggtgggcacg ctcgctcgga ttgacaagga tgaactcggc       60

aaagccatcc agaactcact ggttggggag cccattctgc agaatgtgct gggatcggtc      120

acagctgtga accggggcct cttgggctca ggagggctgc ttggaggagg cggcttgctg      180

ggccacggag gggtttttgg cgttgtcgag gagctctctg gtctgaagat tgaggagctc      240

acgctgccaa aggtgttgct gaagctgctg ccgggatttg gggtgcagct gagcctgcac      300

accaaagtgg gcatgcattg ctctggcccc cttggtggcc ttctgcagct ggctgcggag      360

gtgaacgtga catcgcgggt ggcgctggcc gtgagctcaa ggggcacacc catccttatc      420

ctcaagcgct gcagcacgct cctgggccac atcagcctgt tctcagggct gctgcccaca      480

ccactctttg gggtcgtgga acagatgctc ttcaaggtgc ttccgggact gctgtgcccc      540

gtggtggaca gtgtgctggg tgtggtgaat gagctcctgg gggctgtgct gggcctggtg      600

tcccttgggg ctcttgggtc cgtggaattc tctctggcca cattgcctct catctccaac      660

cagtacatag aactggacat caaccctatc gtgaagagtg tagctggtga tatcattgac      720

ttccccaagt cccgtgcccc agccaaggtg ccccccaaga aggaccacac atcccaggtg      780

atggtgccac tgtacctctt caacaccatg tttggactcc tgcagaccaa cggcgccctc      840

gacatggaca tcacccctga gctggttccc agcgatgtcc cactgacaac tacagacctg      900

gcagctttgc tccctgaggc cctggggaag ctgcccctgc accagcaact cctactgttc      960

ctgcgggtga gggaagctcc cacggtcaca ctccacaaca agaaggcctt ggtctccctc     1020

ccagccaaca tccatgtgct gttctatgtc cctaagggga cccctgaatc cctctttgag     1080

ctgaactccg tcatgactgt gcgtgcccag ctggctccct cggctaccaa gctgcacatc     1140

tccctgtccc tggaacggct cagtgtcaag gtggcctcct cctttaccca tgcctttgac     1200

ggatcgcgtt tagaagaatg gctcagccat gtggtcgggg cagtgtatgc accaaagctt     1260

aacgtggccc tggatgttgg aatttccctg cctaaggttc ttaatatcaa tttttccaat     1320

tcagttctgg agatcgtaga gaatgctgtt gtgctgaccg tggcatcc                  1368


<210>  5414
<211>  537
<212>  DNA
<213>  Homo Sapiens

<400>  5414
caagaggtgg atacagattt tgatttccca gaagaagata aaaaagaaga atttgaagag       60

tgtttggaaa aattttttag tacagggccc gccagaccac ctaccaaaga aaaagtcaaa      120

agacgtgtcc ttattgaacc tggaatgcca ctaaatcata tagagtactg taaccatgaa      180

atcatgggaa aaaatgttta ctacaaacac cgttgggtgg cagaacatta cttccttctt      240

atgcaatatg acgagctcca aaaaatctgt tacaacagat ttgtgccatg taagaatgga      300

attaggaaat gtaacaggag caaaggtctt gtagaaggag tgtattgtaa tttaacagaa      360

gcatctgaaa taccagcgtg taaatacgaa tcactttata ggaagggcta cgtccttatc      420

acttgttcat ggcaaaatga aatgcaaaaa cgtattcctc atactataaa tgatctcgtg      480

gagccacctg aacacagaag tttcctcagt gaggatggtg tctttgtcat accgccc         537


<210>  5415
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  5415
gcctaccgcc atcctgattt cccgttattg gaaaaagctc agcaactgct ccaaagtaca       60

ggatcccctt actccaccaa ttgctggtta tgtactagct cttccactga aacaccaggg      120

acagcttatc cagcctcgcc cagagaatgg acaagcatag aggcggaatt acatatttcc      180

tatcgatggg accctaatct gaaaggactg atgaggcctg caaatagtct tctttcaaca      240

gtaaagcaag atttccctga tatccgccag aaacctccca ttttcggacc catctttact      300

aatatcaacc taatgggaat agcccctatt tgtgttatgg ccaaaaggaa aaatggaaca      360

aatgtaggca ctcttccaag tacagtctgt aatgttactt tcactgtaga ttctaaccaa      420

cagacttacc aaacatacac ccacaaccaa ttccgccatc aaccaagatt ccccaaacct      480

ccaaatatta cttttcctca gggaactttg ctagataaat ccagccggtt ttgccaggga      540

cgcccaagct catgcagtac tcgaaacttc tggttccggc ctgctgatta taaccaatgt      600

ctgcaaattt ccaacctcag ctctacagcg gaatgggttc tattggacca aactcgaaat      660

tctctttttt gggaaaataa aaccaaggga gctaaccaga gccaaacacc ctgcgtccaa      720

gtcttagcag gcatgactat agccaccagc tacctgggca tatcagcagt ctcagaattt      780

tttggaacct ccctcacccc cttatttcat ttccatatct ctacatgcct taaaactcaa      840

ggagcctttt atatttgtgg ccagtcgatt caccaatgcc tccccagtaa ctggactgga      900

acttgtacca taggctatgt aaccccagac atcttcatag cccctggcaa tctctctctt      960

ccaataccaa tctatgggaa ttccccgttg cccagggtga ggagggcaat ccatttcatt     1020

ccccttctcg cgggactcgg cattctagct ggtacgggaa ccggaattgc tggaatcaca     1080

aaagcttccc tcacctatag ccagctctca aaggaaatag ccaacaacat tgacaccatg     1140

gctaaagcct taacgaccat gcaagaacaa atcgactctt tagcagccgt agtccttcaa     1200

aatcgtcgag gactagacat gttaacggca gcacagggag gaatttgttt ggccttagat     1260

gaaaaatgtt gcttttgggt aaatcaatca ggaaaagtac aagacaacat cagacaactc     1320

ctaaatcaag cctccagttt acgggaacga gccactcagg gttggttaaa ttgggaagga     1380

acttggaaa                                                             1389


<210>  5416
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  5416
tggcccgggc tgcccaggag gccctgtgtg cactgctgcc gcccggcctg gccccctgga       60

ccctatgccc gggtgagtga cagggacctg tggagggggg acctgtggag ggggctgcct      120

cgagtacggc ccactataga catcgaaatc ctcaaaggtg agaagggtga ggccggcgtc      180

cgaggtcggg ccggcaggag cgggaaagag gggccgccag gcgcccgggg cctgcagggc      240

cgcagaggcc agaaggggca ggtggggccg ccgggcgccg cgtgccgacg tgcctacgcc      300

gccttctccg tgggccggcg cgagggcctg cacagctccg accacttcca ggcggtgccc      360

ttcgacacgg agctggtgaa cctggacggc gccttcgacc tggccgcggg ccgcttcctc      420

tgcacggtgc ccggcgtcta cttcctcagc ctcaacgtgc acacctggaa ctacaaggag      480

acctacctgc acatcatgct gaaccggcgg cccgcggccg tgctctacgc gcagcccagc      540

gagcgcagcg tcatgcaggc ccagagcctg atgctgctgc tggcggcggg cgacgccgtc      600

tgggtgcgca tgttccagcg cgaccgggac aacgccatct acggcgagca cggagacctc      660

tacatcacct tcagcggcca cctggtcaag ccggccgccg agctg                      705


<210>  5417
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5417
gccaccctgg gtggtcctga ggaagaaagc accattgaga attatgcgtc acgacccgag       60

gcctttaaca ccccgttcct gaacatcgac aaattgcgat ctgcgtttaa ggctgatgag      120

ttcctgaact ggcacgccct ctttgagtct atcaaaagga aacttccttt cctcaactgg      180

gatgcctttc ctaagctgaa aggactgagg agcgcaactc ctgatgccca g               231


<210>  5418
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  5418
gtagatgtaa caacaacaga ggcctttgat tctggagtca tagatgtgca gtcaacaccc       60

acagtcaggg aagagaaatc agccactgac ctgacagcaa aactcttgct tcttgatgaa      120

ttggtgtccc tagaaaatga tgtgattgag acaaagaaga aaaggagttt ctctggtttt      180

gggtctcccc ttgacagact ctcagctggc tctgtagatc acaaaggtaa acagaggaaa      240

gtagtagatc atccaaaaag gcgatttggt atccccatgg atcggattgg tagaaaccgg      300

ctttcaaatt ccagaggc                                                    318


<210>  5419
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  5419
aaggtctttg aaaggtgtga gttggccaga actctgaaaa gattgggaat ggatggctac       60

aggggaatca gcctagcaaa ctggatgtgt ttggccaaat gggagagtgg ttacaacaca      120

cgagctacaa actacaatgc tggagacaga agcactgatt atgggatatt tcagatcaat      180

agccgctact ggtgtaatga tggcaaaacc ccaggagcag ttaatgcctg tcatttatcc      240

tgcagtgctt tgctgcaaga taacatcgct gatgctgtag cttgtgcaaa gagggttgtc      300

cgtgatccac aaggcattag agcatgggtg gcatggagaa atcgttgtca aaacagagat      360

gtccgtcagt atgttcaagg ttgtggagtg                                       390


<210>  5420
<211>  396
<212>  DNA
<213>  Homo Sapiens

<400>  5420
gaaccggtgc agttcaagga ctgcggttct gtggatggag ttataaagga agtgaatgtg       60

agcccatgcc ccacccaacc ctgccagctg agcaaaggac agtcttacag cgtcaatgtc      120

accttcacca gcaatattca gtctaaaagc agcaaggccg tggtgcatgg catcctgatg      180

ggcgtcccag ttccctttcc cattcctgag cctgatggtt gtaagagtgg aattaactgc      240

cctatccaaa aagacaagac ctatagctac ctgaataaac taccagtgaa aagcgaatat      300

ccctctataa aactggtggt ggagtggcaa cttcaggatg acaaaaacca aagtctcttc      360

tgctgggaaa tcccagtaca gatcgtttct catctc                                396


<210>  5421
<211>  429
<212>  DNA
<213>  Homo Sapiens

<400>  5421
gtgtggttgg gaagactgga ccctgagcag cttcttgggc cctggtacgt gcttgcggtg       60

gcctcccggg aaaagggctt tgccatggag aaggacatga agaacgtcgt gggggtggtg      120

gtgaccctca ctccagaaaa caacctgcgg acgctgtcct ctcagcacgg gctgggaggg      180

tgtgaccaga gtgtcatgga cctgataaag cgaaactccg gatgggtgtt tgagaatccc      240

tcaataggcg tgctggagct ctgggtgctg gccaccaact tcagagacta tgccatcatc      300

ttcactcagc tggagttcgg ggacgagccc ttcaacaccg tggagctgta cagtctgact      360

gagacagcca gccaggaggc catggggctc ttcaccaagt ggagcaggag cctgggcttc      420

ctgtcacag                                                              429


<210>  5422
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  5422
gtcaacccca ccgtgttctt cgacattgcc gtcgacggcg agcccttggg ccgcgtctcc       60

tttgagctgt ttgcagacaa ggtcccaaag acagcagaaa attttcgtgc tctgagcact      120

ggagagaaag gatttggtta taagggttcc tgctttcaca gaattattcc agggtttatg      180

tgtcagggtg gtgacttcac acgccataat ggcactggtg gcaagtccat ctatggggag      240

aaatttgaag atgagaactt catcctaaag catacgggtc ctggcatctt gtccatggca      300

aatgctggac ccaacacaaa tggttcccag tttttcatct gcactgccaa gactgagtgg      360

ttggatggca agcatgtggt gtttggcaaa gtgaaagaag gcatgaatat tgtggaggcc      420

atggagcgct ttgggtccag gaatggcaag accagcaaga agatcaccat tgctgactgt      480

ggacaactcg aa                                                          492


<210>  5423
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  5423
agcagcgagg ccgagaccca gcagccgccc gccgcccccc ccgccgcccc cgccctcagc       60

gccgccgaca ccaagcccgg cactacgggc agcggcgcag ggagcggtgg cccgggcggc      120

ctcacatcgg cggcgcctgc cggcggggac aagaaggtca tcgcaacgaa ggttttggga      180

acagtaaaat ggttcaatgt aaggaacgga tatggtttca tcaacaggaa tgacaccaag      240

gaagatgtat ttgtacacca gactgccata aagaagaata accccaggaa gtaccttcgc      300

agtgtaggag atggagagac tgtggagttt gatgttgttg aaggagaaaa gggtgcggag      360

gcagcaaatg ttacaggtcc tggtggtgtt ccagttcaag gcagtaaata tgcagcagac      420

cgtaaccatt atagacgcta tccacgtcgt aggggtcctc cacgcaatta ccagcaaaat      480

taccagaata gtgagagtgg ggaaaagaac gagggatcgg agagtgctcc cgaaggccag      540

gcccaacaac gccggcccta ccgcaggcga aggttcccac cttactacat gcggagaccc      600

tatgggcgtc gaccacagta ttccaaccct cctgtgcagg gagaagtgat ggagggtgct      660

gacaaccagg gtgcaggaga acaaggtaga ccagtgaggc agaatatgta tcggggatat      720

agaccacgat tccgcagggg ccctcctcgc caaagacagc ctagagagga cggcaatgaa      780

gaagataaag aaaatcaagg agatgagacc caaggtcagc agccacctca acgtcggtac      840

cgccgcaact tcaattaccg acgcagacgc ccagaaaacc ctaaaccaca agatggcaaa      900

gagacaaaag cagccgatcc accagctgag aattcgtccg ctcccgaggc tgagcagggc      960

ggggctgag                                                              969


<210>  5424
<211>  1566
<212>  DNA
<213>  Homo Sapiens

<400>  5424
gagggcgtgc agacctgcga agaagttcgg aaacttttcc agtggcggct gctgggagct       60

gtcagggggc tgccggattc gccgcgggca ggacctgatc ttcaggtttg catatccaaa      120

aagcctacat gttgcaccag gaagatggag gagagatatc agattgcggc tcgccaggat      180

atgcagcagt ttcttcaaac gtccagctct acattaaagt ttctaatatc tcgaaatgcg      240

gctgcttttc aagaaaccct tgaaactctc atcaaacaag cagaaaatta caccagtata      300

cttttttgca gtacctacag gaacatggcc ttggaggctg ctgcttcggt tcaggagttc      360

ttcactgatg tggggctgta tttatttggt gcggatgtta atcctgaaga atttgtaaac      420

agattttttg acagtctttt tcctctggtc tacaaccacc tcattaaccc tggtgtgact      480

gacagttccc tggaatactc agaatgcatc cggatggctc gccgggatgt gagtccattt      540

ggtaatattc cccaaagagt aatgggacag atggggaggt ccctgctgcc cagccgcact      600

tttctgcagg cactcaatct gggcattgaa gtcatcaaca ccacagacta tctgcacttc      660

tccaaagagt gcagcagagc cctcctgaag atgcaatact gcccgcactg ccaaggcctg      720

gcgctcacta agccttgtat gggatactgc ctcaatgtca tgcgaggctg cctggcgcac      780

atggcggagc ttaatccaca ctggcatgca tatatccggt cgttggaaga actctcggat      840

gcaatgcatg gaacatacga cattggacac gtgctgctga actttcactt gcttgttaat      900

gatgctgtgt tacaggctca cctcaatgga caaaaattat tggaacaggt aaataggatt      960

tgtggccgcc ctgtaagaac acccacacaa agcccccgtt gttcttttga tcagagcaaa     1020

gagaagcatg gaatgaagac caccacaagg aacagtgaag agacgcttgc caacagaaga     1080

aaagaattta tcaacagcct tcgactgtac aggtcattct atggaggtct agctgatcag     1140

ctttgtgcta atgaattagc tgctgcagat ggacttccct gctggaatgg agaagatata     1200

gtaaaaagtt atactcagcg tgtggttgga aatggaatca aagcccagtc tggaaatcct     1260

gaagtcaaag tcaaaggaat tgatcctgtg ataaatcaga ttattgataa actgaagcat     1320

gttgttcagt tgttacaggg tagatcaccc aaacctgaca agtgggaact tcttcagctg     1380

ggcagtggtg gaggcatggt tgaacaagtc agtggggact gtgatgatga agatggttgc     1440

gggggatcag gaagtggaga agtcaagagg acactgaaga tcacagactg gatgccagat     1500

gatatgaact tcagtgatgt aaagcaaatc catcaaacag acactggcag tactttagac     1560

acaaca                                                                1566


<210>  5425
<211>  1074
<212>  DNA
<213>  Homo Sapiens

<400>  5425
cactaccacc atgtcaccaa gctcgacgag gtggctgcct ctcagcttac cttccctgct       60

gtcacgctgt gcaacctcaa cgagttccgc tttagccaag tctccaagaa tgacctgtat      120

catgctgggg agctgctggc cctgctcaac aacaggtatg agataccaga cacacagatg      180

gcagatgaaa agcagctgga gatactgcag gacaaagcca acttccgcag cttcaaaccc      240

aaacccttca acatgcgtga gttctacgac cgagctgggc acgacattcg agacatgctg      300

ctctcctgcc acttccgggg ggaggtctgc agcgctgaag acttcaaggt ggtcttcaca      360

cgctatggaa agtgctacac gttcaactcg ggccgagatg ggcggccgcg gctgaagacc      420

atgaagggtg ggacgggcaa tgggctggaa atcatgctgg acatccagca ggacgagtac      480

ctgcctgtgt ggggggagac tgacgagacg tccttcgaag caggcatcaa agtgcagatc      540

catagtcagg atgaacctcc tttcatcgac cagctgggct ttggcgtggc cccaggcttc      600

cagacctttg tggcctgcca ggagcagcgg ctcatctacc tgcccccacc ctggggcacc      660

tgcaaagctg ttaccatgga ctcggatttg gatttcttcg actcctacag catcactgcc      720

tgccgcatcg actgtgagac gcgctacctg gtggagaact gcaactgccg catggtgcac      780

atgccagggg atgccccata ctgtactcca gagcagtaca aggagtgtgc agatcctgct      840

ctggacttcc tggtggagaa ggaccaggag tactgcgtgt gtgaaatgcc ttgcaacctg      900

acccgctatg gcaaagagct gtccatggtc aagatcccca gcaaagcctc agccaagtac      960

ctggccaaga agttcaacaa atctgagcaa tacatagggg agaacatcct ggtgctggac     1020

attttctttg aagtcctcaa ctatgagacc attgaacaga agaaggccta tgag           1074


<210>  5426
<211>  177
<212>  DNA
<213>  Homo Sapiens

<400>  5426
tcctccacgc tgcccaccga ctactggaag gtgtctacca tcgacggcac ggtcatcaca       60

accgccacct attgggccaa cctgtggaag gcgtgcgtta ccgactccac gggcgtctcc      120

aactgcaagg acttcccctc catgctggcg ctggacggtt atatacaggc atgtaga         177


<210>  5427
<211>  1800
<212>  DNA
<213>  Homo Sapiens

<400>  5427
caaggtctct taagtctcca agctaaacag gagtactgcc tgaagccaga atgcatcgaa       60

gcggctgctg ccatcttaag taaagtaaat ctgtctgtgg atccttgtga taatttcttc      120

cggttcgctt gtgatggctg gataagcaat aatccaattc ccgaagatat gccaagctat      180

ggggtttatc cttggctgag acataatgtt gacctcaagt tgaaggaact tttggagaaa      240

tcaatcagta gaaggcggga caccgaagcc atacagaaag ccaaaatcct ttattcatcc      300

tgcatgaatg agaaagcgat tgaaaaagca gatgccaagc cactgctaca catcctacgg      360

cattcacctt tccgctggcc cgtgcttgaa tctaatattg gccctgaagg ggtttggtca      420

gagagaaagt tcagccttct gcagacactt gcaacgtttc gtggtcaata cagcaattct      480

gtgttcatcc gtttgtatgt gtcccctgat gacaaagcat ccaatgaaca tatcttgaag      540

ctggaccaag caacactctc cctggccgtg agggaagact accttgataa cagtacagaa      600

gccaagtctt atcgggatgc cctttacaag ttcatggtgg atactgccgt gcttttagga      660

gctaacagtt ccagagcaga gcatgacatg aagtcagtgc tcagattgga aattaagata      720

gctgagataa tgattccaca tgaaaaccga accagcgagg ccatgtacaa caaaatgaac      780

atttctgaac tgagtgctat gattccccag ttcgactggc tgggctacat caagaaggtc      840

attgacacca gactctaccc ccatctgaaa gacatcagcc cctccgagaa tgtggtggtc      900

cgcgtcccgc agtactttaa agatttgttt aggatattag ggtctgagag aaagaagacc      960

attgccaact atttggtgtg gagaatggtt tattccagaa ttccaaacct tagcaggcgc     1020

tttcagtata gatggctgga attctcaagg gtaatccagg ggaccacaac tttgctgcct     1080

caatgggaca aatgtgtaaa ctttattgaa agtgccctcc cttatgttgt tggaaagatg     1140

tttgtagatg tgtacttcca ggaagataag aaggaaatga tggaggaatt ggttgagggc     1200

gttcgctggg cctttattga catgctagag aaagaaaatg agtggatgga tgcaggaacg     1260

aaaaggaaag ccaaagaaaa ggcgagagct gttttggcaa aagttggcta tccagagttt     1320

ataatgaatg atactcatgt taatgaagac ctcaaagcta tcaagttttc agaagccgac     1380

tactttggca acgtcctaca aactcgcaag tatttagcac agtctgattt cttctggcta     1440

agaaaagccg ttccaaaaac agagtggttt acaaatccga cgactgtcaa tgccttctac     1500

agtgcatcca ccaaccagat ccgatttcca gcaggagagc tccagaagcc tttcttttgg     1560

ggaacagaat atcctcgatc tctgagttat ggtgctatag gagtaattgt cggacatgaa     1620

tttacacatg gatttgataa taatggtaga aaatatgata aaaatggaaa cctggatcct     1680

tggtggtcta ctgaatcaga agaaaagttt aaggaaaaaa caaaatgcat gattaaccag     1740

tatagcaact attattggaa gaaagctggc ttaaatgtca aggggaagag gaccctggga     1800


<210>  5428
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  5428
ggggacaccc gaccacgttt cttggagctg cgtaagtctg agtgtcattt cttcaatggg       60

acggagcggg tgcggtacct ggacagatac ttccataacc aggaggagtt cctgcgcttc      120

gacagcgacg tgggggagta ccgggcggtg acggagctgg ggcggcctgt cgccgagtcc      180

tggaacagcc agaaggacct cctggagcag aagcggggcc gggtggacaa ttactgcaga      240

cacaactacg gggttggtga gagcttcaca gtgcagcggc gagtccatcc tcaggtgact      300

gtgtatcctg caaagaccca gcccctgcag caccacaacc tcctggtctg ctctgtgagt      360

ggtttctatc caggcagcat tgaagtcagg tggttccgga acggccagga agagaaggct      420

ggggtggtgt ccacgggcct gatccagaat ggagactgga ccttccagac cctggtgatg      480

ctagaaacag ttcctcggag tggagaggtt tacacttgcc aagtggagca cccaagcgta      540

acgagcgctc tcacagtgga atggagagca cggtctgaat ctgcacagag caag            594


<210>  5429
<211>  2451
<212>  DNA
<213>  Homo Sapiens

<400>  5429
tgtggccttt caacacacgt agaaatagga cacagagctc tggagtttct tcagcttcac       60

aatgggcgtg ttaactacag agagctgtta ctagaacacc aggatgcgta tcaggctgga      120

atcgtgtttc ctgattgttt ttaccctagc atctgcaaag gaggaaaatt ccatgatgtg      180

tctgagagca ctcactggac tccgtttctt aatgcaagcg ttcattatat ccgagagaac      240

tatccccttc cctgggagaa ggacacagag aaactggtag ctttcttgtt tggaattact      300

tctcacatgg cggcagatgt cagctggcat agtctgggcc ttgaacaagg attccttagg      360

accatgggag ctattgattt tcacggctcc tattcagagg ctcattcggc tggtgatttt      420

ggaggagatg tgttgagcca gtttgaattt aattttaatt accttgcacg acgctggtat      480

gtgccagtca aagatctact gggaatttat gagaaactgt atggtcgaaa agtcatcacc      540

gaaaatgtaa tcgttgattg ttcacatatc cagttcttag aaatgtatgg tgagatgcta      600

gctgtttcca agttatatcc cacttactct acaaagtccc cgtttttggt ggaacaattc      660

caagagtatt ttcttggagg actggatgat atggcatttt ggtccactaa tatttaccat      720

ctaacaagct tcatgttgga gaatgggacc agtgactgca acctgcctga gaaccctctg      780

ttcattgcat gtggcggcca gcaaaaccac acccagggct caaaaatgca gaaaaatgat      840

tttcacagaa atttgactac atccctaact gaaagtgttg acaggaatat aaactatact      900

gaaagaggag tgttctttag tgtaaattcc tggaccccgg attccatgtc ctttatctac      960

aaggctttgg aaaggaacat aaggacaatg ttcataggtg gctctcagtt gtcacaaaag     1020

cacgtctcca gccccttagc atcttacttc ttgtcatttc cttatgcgag gcttggctgg     1080

gcaatgacct cagctgacct caaccaggat gggcacggtg acctcgtggt gggcgcacca     1140

ggctacagcc gccccggcca catccacatc gggcgcgtgt acctcatcta cggcaatgac     1200

ctgggcctgc cacctgttga cctggacctg gacaaggagg cccacaggat ccttgaaggc     1260

ttccagccct caggtcggtt tggctcggcc ttggctgtgt tggactttaa cgtggacggc     1320

gtgcctgacc tggccgtggg agctccctcg gtgggctccg agcagctcac ctacaaaggt     1380

gccgtgtatg tctactttgg ttccaaacaa ggaggaatgt cttcttcccc taacatcacc     1440

atttcttgcc aggacatcta ctgtaacttg ggctggactc tcttggctgc agatgtgaat     1500

ggagacagtg aacccgatct ggtcatcggc tccccttttg caccaggtgg agggaagcag     1560

aagggaattg tggctgcgtt ttattctggc cccagcctga gcgacaaaga aaaactgaac     1620

gtggaggcag ccaactggac ggtgagaggc gaggaagact tctcctggtt tggatattcc     1680

cttcacggtg tcactgtgga caacagaacc ttgctgttgg ttgggagccc gacctggaag     1740

aatgccagca ggctgggcca tttgttacac atccgagatg agaaaaagag ccttgggagg     1800

gtgtatggct acttcccacc aaacggccaa agctggttta ccatttctgg agacaaggca     1860

atggggaaac tgggtacttc cctttccagt ggccacgtac tgatgaatgg gactctgaaa     1920

caagtgctgc tggttggagc ccctacgtac gatgacgtgt ctaaggtggc attcctgacc     1980

gtgaccctac accaaggcgg agccactcgc atgtacgcac tcacatctga cgcgcagcct     2040

ctgctgctca gcaccttcag cggagaccgc cgcttctccc gatttggtgg cgttctgcac     2100

ttgagtgacc tggatgatga tggcttagat gaaatcatca tggcagcccc cctgaggata     2160

gcagatgtaa cctctggact gattggggga gaagacggcc gagtatatgt atataatggc     2220

aaagagacca cccttggtga catgactggc aaatgcaaat catggataac tccatgtcca     2280

gaagaaaagg cccaatatgt attgatttct cctgaagcca gctcaaggtt tgggagctcc     2340

ctcatcaccg tgaggtccaa ggcaaagaac caagtcgtca ttgctgctgg aaggagttct     2400

ttgggagccc gactctccgg ggcacttcac gtctatagcc ttggctcaga t              2451


<210>  5430
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  5430
caggactcca cctcagacct gatcccagcc ccacctctga gcaaggtccc tctgcagcag       60

aacttccagg acaaccaatt ccaggggaag tggtatgtgg taggcctggc agggaatgca      120

attctcagag aagacaaaga cccgcaaaag atgtatgcca ccatctatga gctgaaagaa      180

gacaagagct acaatgtcac ctccgtcctg tttaggaaaa agaagtgtga ctactggatc      240

aggacttttg ttccaggttg ccagcccggc gagttcacgc tgggcaacat taagagttac      300

cctggattaa cgagttacct cgtccgagtg gtgagcacca actacaacca gcatgctatg      360

gtgttcttca agaaagtttc tcaaaacagg gagtacttca agatcaccct ctacgggaga      420

accaaggagc tgacttcgga actaaaggag aacttcatcc gcttctccaa atctctgggc      480

ctccctgaaa accacatcgt cttccctgtc ccaatcgacc agtgtatcga cggc            534


<210>  5431
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  5431
gaaaagctac atacccagcc ctcctgcccc gcggtctgcc agcccacgcg ctgccccgcg       60

ctgcccacct gcgcgctggg gaccacgccg gtgttcgacc tgtgccgctg ttgccgcgtc      120

tgccccgcgg ccgagcgtga agtctgcggc ggggcgcagg gccaaccgtg cgccccgggg      180

ctgcagtgcc tccagccgct gcgccccggg ttccccagca cctgcggttg cccgacgctg      240

ggaggggccg tgtgcggcag cgacaggcgc acctacccca gcatgtgcgc gctccgggcc      300

gaaaaccgcg ccgcgcgccg cctgggcaag gtcccggccg tgcctgtgca gtgggggaac      360

tgcggggata cagggaccag aagcgcaggc ccgctcagga ggaattacaa cttcatcgcc      420

gcggtggtgg agaaggtggc gccatcggtg gttcacgtgc agctgtgggg caggttactt      480

cacggcagca ggcttgttcc tgtgtacagt ggctctgggt tcatagtgtc tgaggacggg      540

ctcattatta ccaatgccca tgttgtcagg aaccagcagt ggattgaggt ggtgctccag      600

aatggggccc gttatgaagc tgttgtcaag gatattgacc ttaaattgga tcttgcggtg      660

attaagattg aatcaaatgc tgaacttcct gtactgatgc tgggaagatc atctgacctt      720

cgggctggag agtttgtggt ggctttgggc agcccatttt ctctgcagaa cacagctact      780

gcaggaattg tcagcaccaa acagcgaggg ggcaaagaac tggggatgaa ggattcagat      840

atggactacg tccagattga tgccacaatt aactatggga attctggtgg tcctctggtg      900

aacttggatg gtgatgtgat tggcgtcaat tcattgaggg tgactgatgg aatctccttt      960

gcaattcctt cagatcgagt taggcagttc ttggcagaat accatgagca ccagatgaaa     1020

ggaaaggcgt tttcaaataa gaaatatctg ggtctgcaaa tgctgtccct cactgtgccc     1080

cttagtgaag aattgaaaat gcattatcca gatttccctg atgtgagttc tggggtttat     1140

gtatgtaaag tgtttgaagg aacagctgct caaagctctg gattgagaga tcacgatgta     1200

attgtcaaca taaatgggaa acctattact actacaactg atgttgttaa agctcttgac     1260

agtgattccc tttccatggc tgttcttcgg ggaaaagata atttgctcct gacagtcata     1320

cctgaaacaa tcaat                                                      1335


<210>  5432
<211>  1308
<212>  DNA
<213>  Homo Sapiens

<400>  5432
cgggagcccc ctgcggcgcc gtgtcccgcg cgctgcgacg tgtcgcggtg tcccagcccc       60

cgctgccccg gcggctacgt gcccgacctc tgcaactgct gcctggtgtg cgccgccagc      120

gagggcgagc cctgtggcgg ccctctggac tcgccttgcg gcgagagcct ggagtgcgtg      180

cgcggcctat gccgctgccg ctggtcgcac gccgtgtgtg gcaccgacgg gcacacctat      240

gccaacgtgt gcgcgctgca ggcggccagc cgccgcgcgc tgcagctctc cgggacgccc      300

gtgcgccagc tgcagaaggg cgcctgcccg ttgggtctcc accagctgag cagcccgcgc      360

tacaagttca acttcattgc tgacgtggtg gagaagatcg caccagccgt ggtccacata      420

gagctcttcc tgagacaccc gctgtttggc cgcaacgtgc ccctgtccag cggttctggc      480

ttcatcatgt cagaggccgg cctgatcatc accaatgccc acgtggtgtc cagcaacagt      540

gctgccccgg gcaggcagca gctcaaggtg cagctacaga atggggactc ctatgaggcc      600

accatcaaag acatcgacaa gaagtcggac attgccacca tcaagatcca tcccaagaaa      660

aagctccctg tgttgttgct gggtcactcg gccgacctgc ggcctgggga gtttgtggtg      720

gccatcggca gtcccttcgc cctacagaac acagtgacaa cgggcatcgt cagcactgcc      780

cagcgggagg gcagggagct gggcctccgg gactccgaca tggactacat ccagacggat      840

gccatcatca actacgggaa ctccggggga ccactggtga acctggatgg cgaggtcatt      900

ggcatcaaca cgctcaaggt cacggctggc atctcctttg ccatcccctc agaccgcatc      960

acacggttcc tcacagagtt ccaagacaag cagatcaaag actggaagaa gcgcttcatc     1020

ggcatacgga tgcggacgat cacaccaagc ctggtggatg agctgaaggc cagcaacccg     1080

gacttcccag aggtcagcag tggaatttat gtgcaagagg ttgcgccgaa ttcaccttct     1140

cagagaggcg gcatccaaga tggtgacatc atcgtcaagg tcaacgggcg tcctctagtg     1200

gactcgagtg agctgcagga ggccgtgctg accgagtctc ctctcctact ggaggtgcgg     1260

cgggggaacg acgacctcct cttcagcatc gcacctgagg tggtcatg                  1308


<210>  5433
<211>  780
<212>  DNA
<213>  Homo Sapiens

<400>  5433
tggggattca aggatggaat ttttcataac tccatatggc ttgaacgagc agccggtgtg       60

taccacagag aagcacggtc tggcaaatac aagctcacct acgcagaagc taaggcggtg      120

tgtgaatttg aaggcggcca tctcgcaact tacaagcagc tagaggcagc cagaaaaatt      180

ggatttcatg tctgtgctgc tggatggatg gctaagggca gagttggata ccccattgtg      240

aagccagggc ccaactgtgg atttggaaaa actggcatta ttgattatgg aatccgtctc      300

aataggagtg aaagatggga tgcctattgc tacaacccac acgcaaagga gtgtggtggc      360

gtctttacag atccaaagca aatttttaaa tctccaggct tcccaaatga gtacgaagat      420

aaccaaatct gctactggca cattagactc aagtatggtc agcgtattca cctgagtttt      480

ttagattttg accttgaaga tgacccaggt tgcttggctg attatgttga aatatatgac      540

agttacgatg atgtccatgg ctttgtggga agatactgtg gagatgagct tccagatgac      600

atcatcagta caggaaatgt catgaccttg aagtttctaa gtgatgcttc agtgacagct      660

ggaggtttcc aaatcaaata tgttgcaatg gatcctgtat ccaaatccag tcaaggaaaa      720

aatacaagta ctacttctac tggaaataaa aactttttag ctggaagatt tagccactta      780


<210>  5434
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  5434
aaaacggaca gctcattcat aatggactcg gaccctcgac gctgcatgag gcaccactat       60

gtggattcta tcagtcaccc attgtacaag tgtagctcaa agatggtgct cctggccagg      120

tgcgaggggc actgcagcca ggcgtcacgc tccgagcctt tggtgtcgtt cagcactgtc      180

ctcaagcaac ccttccgttc ctcctgtcac tgctgccggc cccagacttc caagctgaag      240

gcactgcggc tgcgatgctc agggggcatg cgactcactg ccacctaccg gtacatcctc      300

tcctgtcact gcgaggaatg caattcc                                          327


<210>  5435
<211>  1041
<212>  DNA
<213>  Homo Sapiens

<400>  5435
accgactgcc catgcccgga gcctgagctc tgccgcccga ttcgccacca tccagatttc       60

gaggtctttg tgtttgatgt tggacagaaa acttggaaat cttatgattg gtcacagatt      120

acaactgtgg caacatttgg aaaatatgac tcagaactta tgtgctacgc tcattcaaaa      180

ggagccagag tagtacttaa aggagatgta tccttaaagg atatcattga tcctgctttc      240

agagcatcct ggatagctca aaaacttaat ttggccaaaa cacaatatat ggatggaatt      300

aatatagata tagagcaaga agttaattgt ttatcacctg aatatgatgc attaactgct      360

ttagtcaaag aaactacaga ctctttccat cgtgaaattg agggatcaca ggtaaccttt      420

gatgtagctt ggtctccaaa gaacatagac agaagatgct ataattatac tggaatcgca      480

gatgcttgtg acttcctctt tgtgatgtct tatgatgaac aaagtcagat ctggtcagaa      540

tgtattgcag cagccaatgc tccctataat cagacattaa ctggatataa tgactacatc      600

aagatgagca ttaatcctaa gaaacttgta atgggtgttc cttggtatgg ttatgattat      660

acctgcctga atctgtctga ggatcatgtt tgtaccattg caaaagtccc tttccggggg      720

gctccttgta gtgacgctgc aggacgtcag gtgccctaca aaacgatcat gaagcaaata      780

aatagttcta tttctggaaa cctatgggat aaagatcagc gggctcctta ttataactat      840

aaagatcctg ctggccactt tcatcaagta tggtatgata accctcagag tatttcttta      900

aaggcaacat atatacaaaa ctatcgctta cggggcattg gcatgtggaa tgcaaactgt      960

cttgactact ctggagatgc tgtagccaaa cagcaaactg aagaaatgtg ggaagtctta     1020

aagccaaagc tgttacagag a                                               1041


<210>  5436
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  5436
gagtcactcc aggaaagagc tgatgaggct acaacccaga agcagtctgg ggaagacaac       60

caggaccttg ctatctcctt tgcaggaaat ggactctctg ctcttagaac ctcaggttct      120

caggcaagag ccacctgcta ttgccgaact ggccgttgtg ctacccgtga gtccctctcc      180

ggggtgtgtg aaatcagtgg ccgcctctac agactctgct gtcgc                      225


<210>  5437
<211>  1677
<212>  DNA
<213>  Homo Sapiens

<400>  5437
caaaaaggtg gatcaaaagg ccaattgcca agcggatctt cccaatttcc acatggaaaa       60

aagggccagc actattttgg acaaaaagac caacaacata ctaaatccaa aggcagtttt      120

tctattcaac acacatatca tgtagacatc aatgatcatg actggacccg aaaaagtcag      180

cagtatgatt tgaatgccct acataaggcg acaaaatcaa aacaacacct aggtggaagt      240

caacaactgc tcaattataa acaagaaggc agagaccatg ataaatcaaa aggtcatttt      300

cacatgatag ttatacatca taaaggaggc caagctcatc atgggacaca aaatccttct      360

caagatcagg ggaatagccc atctggaaag ggattatcca gtcaatgttc aaacacagaa      420

aaaaggctat gggttcatgg actaagtaaa gaacaagctt cagcctctgg tgcacaaaaa      480

ggtagaacac aaggtggatc ccaaagcagt tatgttctcc aaactgaaga actagtagtt      540

aacaaacaac aacgtgagac taaaaattct catcaaaata aagggcatta ccaaaatgtg      600

gttgacgtga gagaggaaca ttcaagtaaa ctacaaactt cactccatcc tgcacatcaa      660

gacagactcc aacatggacc caaagacatt tttactaccc aagatgagct cctagtatat      720

aacaagaatc aacaccagac aaaaaatctc aatcaagatc aagagcatgg ccggaaggca      780

cataaaatat catacccgtc ttcacgtaca gaagaaagac aacttcacca tggagaaaag      840

agtgtacaga aagatgtatc caaaggcagc atttctatcc aaactgaaga gaaaatacat      900

ggcaagtctc aaaaccaggt aacaattcat agtcaagatc aagagcatgg ccataaggaa      960

aataaaatat cataccaatc ttcaagtaca gaagaaagac atctcaactg tggagaaaag     1020

ggcatccaga aaggtgtatc caaaggcagt atttcgatcc aaactgaaga gcaaatacat     1080

ggcaagtctc aaaaccaggt aagaattcct agtcaagctc aagagtatgg ccataaggaa     1140

aataaaatat cataccaatc ttcgagtaca gaagaaagac gtctcaacag tggagaaaag     1200

gatgtacaga aaggtgtatc caaaggcagt atttctatcc aaactgaaga gaaaatacat     1260

ggcaagtctc aaaaccaggt aacaattcct agtcaagatc aagagcatgg ccataaggaa     1320

aataaaatgt cataccaatc ttcaagtaca gaagaaagac gactcaacta tggaggaaag     1380

agcacgcaga aagatgtatc ccaaagcagt atttctttcc aaattgaaaa gctagtagaa     1440

ggcaagtctc aaatccagac accaaatcct aatcaagatc aatggtctgg ccaaaatgca     1500

aaaggaaagt ctggtcaatc tgcagatagc aaacaagacc tactcagtca tgaacaaaaa     1560

ggcagataca aacaggaatc cagtgagtca cataatattg taattactga gcatgaggtt     1620

gcccaagatg atcatttgac acaacaatat aatgaagaca gaaatccaat atctaca        1677


<210>  5438
<211>  1497
<212>  DNA
<213>  Homo Sapiens

<400>  5438
gaatggatca agttcgcagc agcctgtcgt gaaggtgaag acaactcaaa gaggaaccca       60

atcgccaaaa ttcactcaga ttgtgctgca aaccagcaag ttacataccg catctctgga      120

gtaggaattg atcagccacc atatgggatc tttgtcatta atcagaaaac tggtgaaatt      180

aatataacat ccatagttga tcgagaggtc actcctttct tcattatcta ctgccgagct      240

ctgaactcaa tgggccaaga tttagagagg cctctagagc tcagagtcag ggttttggat      300

ataaatgaca accctccagt gttttcaatg gctacatttg caggacaaat agaagaaaat      360

tctaatgcaa atacactggt gatgatactc aatgctactg acgcagatga accgaacaat      420

ttgaactcaa aaatagcctt caagattata agacaagaac cttcagattc accaatgttt      480

attatcaaca gaaatactgg agaaattcga acgatgaata attttctaga cagagagcaa      540

tacggccagt atgctcttgc tgtaagaggc tctgaccgag atggtggggc agatggcatg      600

tcagcggaat gtgagtgcaa cattaaaatc ctcgatgtca atgataatat cccttacatg      660

gaacagtctt catataccat agaaattcaa gaaaatactc taaattcaaa tttgctcgag      720

attagagtaa ttgatttgga tgaagagttc tcagctaact ggatggcagt aattttcttt      780

atctctggaa atgaaggaaa ttggtttgag atagaaatga atgaaagaac aaatgtggga      840

attttaaagg ttgttaagcc cttagattat gaagctatgc agagtctgca actcagtatt      900

ggtgtcagaa ataaagctga atttcatcat tcaattatgt ctcaatataa actgaaagca      960

tctgcaattt ctgtgactgt gttaaatgta attgaaggcc cagtgtttcg tccaggttca     1020

aagacatatg ttgtaactgg taatatggga tcaaatgata aagtgggaga ctttgtagct     1080

actgacctgg acacaggtag accttcaacg actgttaggt atgtaatggg aaataatcca     1140

gctgacctgc tagctgttga ttcaagaaca ggcaaactca ctttgaaaaa taaagttacc     1200

aaggaacagt acaatatgct cggaggaaaa taccaaggaa cgattctctc tatagatgat     1260

aatcttcaaa gaacttgcac tggtacaatt aatattaaca ttcaaagttt tggtaatgac     1320

gacaggacta atacagagcc gaacactaaa attactacca atactggcag acaagaaagt     1380

acttcttcca ctaactatga taccagcaca acttctactg actctagcca agtatattct     1440

tctgaacccg gaaacggagc caaagatttg ttatcagaca atgtacattt tggtcct        1497


<210>  5439
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5439
gtcaccgtgc aggatggaaa tttctccttt tctctggagt cagtgaagaa gctcaaagac       60

ctccaggagc cccaggagcc cagggttggg aaactcagga actttgcacc catccctggt      120

gaacctgtgg ttcccatcct ctgtagcaac ccgaactttc cagaagaact caagcctctc      180

tgcaaggagc ccaatgccca ggagatactt cagaggctgg aggaaatcgc tgaggacccg      240

ggcacatgtg aaatctgtgc ctacgctgcc tgtaccggat gc                         282


<210>  5440
<211>  2127
<212>  DNA
<213>  Homo Sapiens

<400>  5440
aagggcgacg ccaagccgga ggacaacctt ttagtcctca cggtggccac taaggagacc       60

gagggattcc gtcgcttcaa gcgctcagct cagttcttca actacaagat ccaggcgctt      120

ggcctagggg aggactggaa tgtggagaag gggacgtcgg caggtggagg gcagaaggtc      180

cggctgctga agaaagctct ggagaagcac gcagacaagg aggatctggt cattctcttc      240

acagacagct atgacgtgct gtttgcatcg gggccccggg agctcctgaa gaagttccgg      300

cagtccagga gccaggtggt cttctctgct gaggagctca tctacccaga ccgcaggctg      360

gagaccaagt atccggtggt gtccgatggc aagaggttcc tgggctctgg aggcttcatc      420

ggttatgccc ccaacctcag caaactggtg gccgagtggg agggccagga cagcgacagc      480

gatcagctgt tttacaccaa gatcttcttg gacccggaga agagggagca gatcaatatc      540

accctggacc accgctgccg tatcttccag aacctggatg gagccttgga tgaggtcgtg      600

ctcaagtttg aaatgggcca tgtgagagcg aggaacctgg cctatgacac cctcccggtc      660

ctgatccatg gcaacgggcc aaccaagctg cagttgaact acctgggcaa ctacatcccg      720

cgcttctgga ccttcgaaac aggctgcacc gtgtgtgacg aaggcttgcg cagcctcaag      780

ggcattgggg atgaagctct gcccacggtc ctggtcggcg tgttcatcga acagcccacg      840

ccgtttgtgt ccctgttctt ccagcggctc ctgcggctcc actaccccca gaaacacatg      900

cgacttttca tccacaacca cgagcagcac cacaaggctc aggtggaaga gttcctggca      960

cagcatggca gcgagtacca gtctgtgaag ctggtgggcc ctgaggtgcg gatggcgaat     1020

gcagatgcca ggaacatggg cgcagacctg tgccggcagg accgcagctg cacctactac     1080

ttcagcgtgg atgctgacgt ggccctgacc gagcccaaca gcctgcggct gctgatccaa     1140

cagaacaaga acgtcattgc cccgctgatg acccggcatg ggaggctgtg gtcgaacttc     1200

tggggggctc tcagtgcaga tggctactat gcccgttccg aggactacgt ggacattgtg     1260

caggggcggc gtgttggtgt ctggaatgtg ccctatattt caaacatcta cttgatcaag     1320

ggcagtgccc tgcggggtga gctgcagtcc tcagatctct tccaccacag caagctggac     1380

cccgacatgg ccttctgtgc caacatccgg cagcaggatg tgttcatgtt cctgaccaac     1440

cggcacaccc ttggccatct gctctcccta gacagctacc gcaccaccca cctgcacaac     1500

gacctctggg aggtgttcag caaccccgag gactggaagg agaagtacat ccaccagaac     1560

tacaccaaag ccctggccgg gaagctggtg gagacgccct gcccggatgt ctattggttc     1620

cccatcttca cggaggtggc ctgtgatgag ctggtggagg agatggagca ctttggccag     1680

tggtctctgg gcaacaacaa ggacaaccgc atccagggtg gctacgagaa cgtgccgact     1740

attgacatcc acatgaacca gatcggcttt gagcgggagt ggcacaaatt cctgctggag     1800

tacattgcgc ccatgacgga gaagctctac cccggctact acaccagggc ccagtttgac     1860

ctggcctttg tcgtccgcta caagcctgat gagcagccct cactgatgcc acaccatgat     1920

gcctccacct tcaccatcaa catcgccctg aaccgagtcg gggtggatta cgagggcggg     1980

ggctgtcggt tcctgcgcta caactgttcc atccgagccc caaggaaggg ctggaccctc     2040

atgcaccctg gacgactcac gcattaccat gaggggctcc ccaccaccag gggcacccgc     2100

tacatcgcag tctccttcgt cgatccc                                         2127


<210>  5441
<211>  1233
<212>  DNA
<213>  Homo Sapiens

<400>  5441
gccgtgttca cggtgggggt cctgggcccc tgggcttgcg accccatctt ctctcgggct       60

cgcccggacc tggccgcccg cctggccgcc gcccgcctga accgcgaccc cggcctggca      120

ggcggtcccc gcttcgaggt agcgctgctg cccgagcctt gccggacgcc gggctcgctg      180

ggggccgtgt cctccgcgct ggcccgcgtg tcgggcctcg tgggtccggt gaaccctgcg      240

gcctgccggc cagccgagct gctcgccgaa gaagccggga tcgcgctggt gccctggggc      300

tgcccctgga cgcaggcgga gggcaccacg gcccctgccg tgacccccgc cgcggatgcc      360

ctctacgccc tgcttcgcgc attcggctgg gcgcgcgtgg ccctggtcac cgccccccag      420

gacctgtggg tggaggcggg acgctcactg tccacggcac tcagggcccg ggggctgcct      480

gtcgcctccg tgacttccat ggagcccttg gacctgtctg gagcccggga ggccctgagg      540

aaggttcggg acgggcccag ggtcacagca gtgatcatgg tgatgcactc ggtgctgctg      600

ggtggcgagg agcagcgcta cctcctggag gccgcagagg agctgggcct gaccgatggc      660

tccctggtct tcctgccctt cgacacgatc cactacgcct tgtccccagg cccggaggcc      720

ttggccgcac tcgccaacag ctcccagctt cgcagggccc acgatgccgt gctcaccctc      780

acgcgccact gtccctctga aggcagcgtg ctggacagcc tgcgcagggc tcaagagcgc      840

cgcgagctgc cctctgacct caatctgcag caggtctccc cactctttgg caccatctat      900

gacgcggtct tcttgctggc aaggggcgtg gcagaagcgc gggctgccgc aggtggcaga      960

tgggtgtccg gagcagctgt ggcccgccac atccgggatg cgcaggtccc tggcttctgc     1020

ggggacctag gaggagacga ggagccccca ttcgtgctgc tagacacgga cgcggcggga     1080

gaccggcttt ttgccacata catgctggat cctgcccggg gctccttcct ctccgccggt     1140

acccggatgc acttcccgcg tgggggatca gcacccggac ctgacccctc gtgctggttc     1200

gatccaaaca acatctgcgg tggaggactg gag                                  1233


<210>  5442
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  5442
caagtgaaac cttgtgattt tccagacatt aaacatggag gtctatttca tgagaatatg       60

cgtagaccat actttccagt agctgtagga aaatattact cctattactg tgatgaacat      120

tttgagactc cttcaggaag ttactgggat tacattcatt gcacacaaaa tgggtggtca      180

ccagcagtac catgtctcag aaaatgttat tttccttatt tggaaaatgg atataatcaa      240

aattatggaa gaaagtttgt acagggtaac tctacagaag ttgcctgcca tcctggctac      300

ggtcttccaa aagcgcagac cacagttaca tgtacggaga aaggctggtc tcctactccc      360

agatgcatcc gtgtcagaac atgctcaaaa tcagatatag aaattgaaaa tggattcatt      420

tccgaatctt cctctattta tattttaaat aaagaaatac aatataaatg taaaccagga      480

tatgcaacag cagatggaaa ttcttcagga tcaattacat gtttgcaaaa tggatggtca      540

gcacaaccaa tttgcattaa ttcttcagaa aagtgtgggc ctcctccacc tattagcaat      600

ggtgatacca cctcctttct actaaaagtg tatgtgccac agtcaagagt cgagtaccaa      660

tgccagccct actatgaact tcagggttct aattatgtaa catgtagtaa tggagagtgg      720

tcggaaccac caagatgcat acatccatgt ataataactg aagaaaacat gaataaaaat      780

aacataaagt taaaaggaag aagtgacaga aaatattatg caaaaacagg ggataccatt      840

gaatttatgt gtaaattggg atataatgca aatacatcaa ttctatcatt tcaagcagtg      900

tgtcgggaag ggatagtgga ataccccaga tgcgaa                                936


<210>  5443
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  5443
gagaaaccct ccccctgcca gtgctccagg ctgagccccc ataacaggac gaactgcggc       60

ttccctggaa tcaccagtga ccagtgtttt gacaatggat gctgtttcga ctccagtgtc      120

actggggtcc cctggtgttt ccaccccctc ccaaagcaag agtcggatca gtgcgtcatg      180

gaggtctcag accgaagaaa ctgtggctac ccgggcatca gccccgagga atgcgcctct      240

cggaagtgct gcttctccaa cttcatcttt gaagtgccct ggtgcttctt cccgaagtct      300

gtggaagact gccattac                                                    318


<210>  5444
<211>  936
<212>  DNA
<213>  Homo Sapiens

<400>  5444
gaagcaacat tttgtgattt tccaaaaata aaccatggaa ttctatatga tgaagaaaaa       60

tataagccat tttcccaggt tcctacaggg gaagttttct attactcctg tgaatataat      120

tttgtgtctc cttcaaaatc attttggact cgcataacat gcacagaaga aggatggtca      180

ccaacaccaa agtgtctcag actgtgtttc tttccttttg tggaaaatgg tcattctgaa      240

tcttcaggac aaacacatct ggaaggtgat actgtgcaaa ttatttgcaa cacaggatac      300

agacttcaaa acaatgagaa caacatttca tgtgtagaac ggggctggtc cacccctccc      360

aaatgcaggt ccactgacac ttcctgtgtg aatccgccca cagtacaaaa tgctcatata      420

ctgtcgagac agatgagtaa atatccatct ggtgagagag tacgttatga atgtaggagc      480

ccttatgaaa tgtttgggga tgaagaagtg atgtgtttaa atggaaactg gacagaacca      540

cctcaatgca aagattctac gggaaaatgt gggccccctc cacctattga caatggggac      600

attacttcat tcccgttgtc agtatatgct ccagcttcat cagttgagta ccaatgccag      660

aacttgtatc aacttgaggg taacaagcga ataacatgta gaaatggaca atggtcagaa      720

ccaccaaaat gcttacatcc gtgtgtaata tcccgagaaa ttatggaaaa ttataacata      780

gcattaaggt ggacagccaa acagaagctt tatttgagaa caggtgaatc agctgaattt      840

gtgtgtaaac ggggatatcg tctttcatca cgttctcaca cattgcgaac aacatgttgg      900

gatgggaaac tggagtatcc aacttgtgca aaaaga                                936


<210>  5445
<211>  1986
<212>  DNA
<213>  Homo Sapiens

<400>  5445
gtgttttacg ctgaacgata ccaaatgccc acaggcataa aaggcccact acccaacacc       60

aagacacagt tcttcattcc ctacaccata aagagtaaag gtatagcagt aagaggagag      120

caaggtactc ctggtccacc aggccctgct ggacctcgag ggcacccagg tccttctgga      180

ccaccaggaa aaccaggcta cggaagtcct ggactccaag gagagccagg gttgccagga      240

ccaccgggac catcagctgt agggaaacca ggtgtgccag gactcccagg aaaaccagga      300

gagagaggac catatggacc aaaaggagat gttggaccag ctggcctacc aggaccccgg      360

ggcccaccag gaccacctgg aatccctgga ccggctggaa tttctgtgcc aggaaaacct      420

ggacaacagg gacccacagg agccccagga cccaggggct ttcctggaga aaagggtgca      480

ccaggagtcc ctggtatgaa tggacagaaa ggggaaatgg gatatggtgc tcctggtcgt      540

ccaggtgaga ggggtcttcc aggccctcag ggtcccacag gaccatctgg ccctcctgga      600

gtgggaaaaa gaggtgaaaa tggggttcca ggacagccag gcatcaaagg tgatagaggt      660

tttccgggag aaatgggacc aattggccca ccaggtcccc aaggccctcc tggggaacga      720

gggccagaag gcattggaaa gccaggagct gctggagccc caggccagcc agggattcca      780

ggaacaaaag gtctccctgg ggctccagga atagctgggc ccccagggcc tcctggcttt      840

gggaaaccag gcttgccagg cctgaaggga gaaagaggac ctgctggcct tcctgggggt      900

ccaggtgcca aaggggaaca agggccagca ggtcttcctg ggaagccagg tctgactgga      960

ccccctggga atatgggacc ccaaggacca aaaggcatcc cgggtagcca tggtctccca     1020

ggccctaaag gtgagacagg gccagctggg cctgcaggat accctggggc taagggtgaa     1080

aggggttccc ctgggtcaga tggaaaacca gggtacccag gaaaaccagg tctcgatggt     1140

cctaagggta acccagggtt accaggtcca aaaggtgatc ctggagttgg aggacctcct     1200

ggtctcccag gccctgtggg cccagcagga gcaaagggaa tgcccggaca caatggagag     1260

gctggcccaa gaggtgcccc tggaatacca ggtactagag gccctattgg gccaccaggc     1320

attccaggat tccctgggtc taaaggggat ccaggaagtc ccggtcctcc tggcccagct     1380

ggcatagcaa ctaagggcct caatggaccc accgggccac cagggcctcc aggtccaaga     1440

ggccactctg gagagcctgg tcttccaggg ccccctgggc ctccaggccc accaggtcaa     1500

gcagtcatgc ctgagggttt tataaaggca ggccaaaggc ccagtctttc tgggacccct     1560

cttgttagtg ccaaccaggg ggtaacagga atgcctgtgt ctgcttttac tgttattctc     1620

tccaaagctt acccagcaat aggaactccc ataccatttg ataaaatttt gtataacagg     1680

caacagcatt atgacccaag gactggaatc tttacttgtc agataccagg aatatactat     1740

ttttcatacc acgtgcatgt gaaagggact catgtttggg taggcctgta taagaatggc     1800

acccctgtaa tgtacaccta tgatgaatac accaaaggct acctggatca ggcttcaggg     1860

agtgccatca tcgatctcac agaaaatgac caggtgtggc tccagcttcc caatgccgag     1920

tcaaatggcc tatactcctc tgagtatgtc cactcctctt tctcaggatt cctagtggct     1980

ccaatg                                                                1986


<210>  5446
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5446
atggaagatg agaagcccaa ggtcaacccc aaactctaca tgtgtgtgtg tgaaggtctc       60

tcctgcggta atgaggacca ctgtgaaggc cagcagtgct tttcctcact gagcatcaac      120

gatggcttcc acgtctacca gaaaggctgc ttccaggttt atgagcaggg aaagatgacc      180

tgtaagaccc cgccgtcccc tggccaagct gtggagtgct gccaagggga ctggtgtaac      240

aggaacatca cggcccagct gcccactaaa ggaaaatcct tccctggaac acagaatttc      300

cacttggag                                                              309


<210>  5447
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  5447
gacaagaaca cgacccagca cccgaacgtg acgactttag cgcccatctc caacgtaacc       60

tcggcgccgg tgacgtccct cccgctggtc accactccgg caccagaaac ctgtgaaggt      120

cgaaacagct gcgtttcctg ttttaatgtt agcgttgtta atactacctg cttttggata      180

gaatgtaaag atgagagcta ttgttcacat aactcaacag ttagtgattg tcaagtgggg      240

aacacgacag acttctgttc cgtttccacg gccactccag tgccaacagc caattctaca      300

gctaaaccca cagttcagcc ctccccttct acaacttcca agacagttac tacatcaggt      360

acaacaaata acactgtgac tccaacctca caacctgtgc gaaagtctac ctttgat         417


<210>  5448
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  5448
atcgccgaaa atgaagatgc cctcctcaga catttgttcc aaggttatca gaaatgggtc       60

cgccctgtat tacattctaa tgacaccata aaagtatatt ttggattgaa aatatcccag      120

cttgtagatg tggatgaaaa gaatcagctg atgacaacca atgtgtggct caaacaggaa      180

tggacagacc acaagttacg ctggaatcct gatgattatg gtgggatcca ttccattaaa      240

gttccatcag aatctctgtg gcttcctgac atagttctct ttgaaaatgc tgacggccgc      300

ttcgaaggct ccctgatgac caaggtcatc gtgaaatcaa acggaactgt tgtctggacc      360

cctcccgcca gctacaaaag ctcctgcacc atggacgtca cgtttttccc gttcgaccga      420

cagaactgct ccatgaagtt tggatcctgg acttatgatg gcaccatggt tgacctcatt      480

ttgatcaatg aaaatgtcga cagaaaagac ttcttcgata acggagaatg ggaaatactg      540

aatgcaaagg ggatgaaggg gaacagaagg gacggcgtgt actcctatcc ctttatcacg      600

tattccttcg tcctgagacg cctg                                             624


<210>  5449
<211>  1806
<212>  DNA
<213>  Homo Sapiens

<400>  5449
atagatgttt ctcagttggt aaatcctgcc tttccaggca ctgtcacttg cgatgaaagg       60

gaaataacag tggagttccc aagcagtcct ggcaccaaga aatggcatgc atctgtggtg      120

gatcctcttg gtctcgacat gccgaactgc acttacatcc tggacccaga aaagctcacc      180

ctgagggcta cctatgataa ctgtaccagg agagtgcatg gtggacacca gatgaccatc      240

agagtcatga acaacagtgc tgccttaaga cacggagctg tcatgtatca gttcttctgt      300

ccagctatgc aagtagaaga gacccagggg ctttcagcat ctacaatctg ccagaaggat      360

ttcatgtctt tttccttgcc acgggtcttc tctggcttgg ctgatgacag taaggggacc      420

aaagttcaga tgggatggag cattgaggtt ggtgatggtg caagagccaa aactctgacc      480

ctgccagagg ccatgaagga aggcttcagc ctcttgattg acaaccacag gatgaccttc      540

catgtgccat tcaatgccac tggagtgact cactatgtgc aaggtaacag tcatctctac      600

atggtgtctc tgaagcttac atttatatct cctggacaga aggtgatctt ctcttcacaa      660

gctatttgtg caccagatcc tgtgacctgc aatgccacac acatgactct caccatacca      720

gagtttcctg ggaagcttaa gtctgtgagc tttgaaaacc agaacattga tgtgagccag      780

ctgcatgaca atggaattga tctagaagca acaaatggca tgaaattgca tttcagcaaa      840

actctgctca aaacgaaatt atctgaaaaa tgcctactcc atcagttcta cttagcttca      900

ctcaagctga cctttctcct tcggccagag acagtatcca tggtgatcta tcctgagtgt      960

ctctgtgagt cacccgtttc tatagttaca ggggagctgt gcacccagga tgggtttatg     1020

gacgtcgagg tctacagcta ccaaacacaa ccagctcttg acctgggtac tctgagggtg     1080

ggaaactcat cctgccagcc tgtctttgag gctcagtctc aggggctggt acggttccac     1140

atacccctga atggatgtgg aacgagatat aagttcgaag atgataaagt cgtctatgaa     1200

aacgaaatac atgctctctg gacggatttt cctccaagca aaatatctag agacagtgag     1260

ttcagaatga cagtgaagtg ttcttatagc aggaatgaca tgctactaaa catcaacgtt     1320

gaaagcctta ctcctccagt ggcctcagtg aagttgggtc catttacctt gatcctgcaa     1380

agctacccag ataattccta ccaacaacct tatggggaaa acgagtaccc tctagtgaga     1440

ttcctccgcc aaccaattta catggaagtg agagtcctaa acagggatga ccccaacatc     1500

aagctggtct tagatgactg ctgggcgacg tccaccatgg atccagactc tttcccccag     1560

tggaacgttg tcgtggatgg ctgtgcatat gacctggaca actaccagac caccttccat     1620

ccagtcggct cctctgtgac ccatcctgat cactatcaga ggtttgacat gaaggctttt     1680

gcctttgtat cagaagccca cgtgctctct agcctggtct acttccactg cagtgcctta     1740

atctgtaatc gactctcccc tgactcccca ctgtgttctg tgacctgccc tgtgtcctct     1800

aggcac                                                                1806


<210>  5450
<211>  1851
<212>  DNA
<213>  Homo Sapiens

<400>  5450
ctcccggaag gggtggccaa tggcatcgag gtctacagta ccaaaatcaa ctccaaggtg       60

acctcccgtt ttgctcacaa tgttgtcacc atgagagccg tcaaccgtgc agacacggcc      120

aaggaggttt cctttgatgt ggagctgccc aagacggcct tcatcaccaa cttcaccttg      180

accatcgacg gtgttaccta ccctgggaat gtcaaggaga aggaagttgc caagaagcag      240

tatgaaaagg ctgtgtccca gggcaagacg gccggcttgg tcaaggcctc tgggaggaag      300

ttggagaagt tcacagtctc ggtcaacgtg gctgcaggca gcaaagtcac cttcgagcta      360

acctacgagg agctgctgaa gaggcacaag ggcaagtacg agatgtacct caaggtccag      420

cctaagcaac tggtcaaaca ctttgagatc gaggtagaca tcttcgagcc tcagggaatc      480

agcatgctgg atgctgaggc ctctttcatc accaacgacc tcctgggaag cgccctcacc      540

aagtccttct cagggaaaaa gggccatgtg tccttcaagc ccagcttaga ccaacagcgt      600

tcatgcccaa cctgtacaga ctccctcctc aatggagatt tcactatcac ctatgacgtg      660

aacagagaat ctcctggcaa cgtgcagata gtcaatggct acttcgtgca cttctttgca      720

cctcaaggcc ttccagtggt gcctaagaac gtggcctttg tgattgacat cagcggctcc      780

atggctggtc ggaaattaga gcagacaaag gaggcccttc tcagaatcct ggaagatatg      840

caagaggaag actatctgaa tttcatcctg ttcagtggag atgtgtccac atggaaagag      900

cacttagtcc aggccacgcc cgagaacctc caggaggcca ggacgtttgt gaagagcatg      960

gaggataaag gaatgaccaa catcaatgac gggctgctga ggggcatcag tatgctgaac     1020

aaggcccgag aggagcacag aatcccagag aggagcacct ccattgtcat catgctgact     1080

gatggggatg ccaatgttgg tgagagcaga cccgaaaaaa tccaagagaa tgtgcggaat     1140

gccatcgggg gcaagttccc cttgtataac ctgggctttg gcaacaatct gaattataac     1200

ttcctggaga acatggccct ggagaaccat gggtttgccc ggcgcattta tgaggactct     1260

gatgccgatt tgcagttgca gggcttctat gaggaggtgg ccaacccact gctgacgggt     1320

gtggagatgg agtaccccga gaacgctatc ctggacctca cccagaacac ttaccagcac     1380

ttctacgatg gctctgagat cgtggtggcc gggcgcctgg tggacgagga catgaacagc     1440

tttaaggcag atgtgaaggg ccatggggcc accaacgacc tgaccttcac agaggaggtg     1500

gacatgaagg agatggagaa ggccctgcag gagcgggact acatcttcgg gaattacatt     1560

gagcggctct gggcctacct caccattgag cagctgctgg agaagcgcaa gaacgcccat     1620

ggcgaggaga aggagaacct cacggcccgg gccctggacc tgtccctcaa gtatcacttt     1680

gtgactccac tgacctcaat ggtggtgacc aagcctgagg acaacgagga tgagagggcc     1740

attgccgaca agcctgggga agatgcagaa gccacaccgg tgagccccgc catgtcctac     1800

ctgaccagct accagcctcc tcaaaacccc tactactatg tggacgggga t              1851


<210>  5451
<211>  1947
<212>  DNA
<213>  Homo Sapiens

<400>  5451
ggctacatcg aggctcttgc agccaatgcc ggaacaggat ttgctgttgc tgagcctcaa       60

atcgcaatgt tttgtgggaa gttaaatatg catgtgaaca ttcagactgg gaaatgggaa      120

cctgatccaa caggcaccaa gagctgcttt gaaacaaaag aagaagttct tcagtactgt      180

caggagatgt atccagagct acagatcaca aatgtgatgg aggcaaacca gcgggttagt      240

attgacaact ggtgccggag ggacaaaaag caatgcaaga gtcgctttgt tacacctttc      300

aagtgtctcg tgggtgaatt tgtaagtgat gtcctgctag ttccagaaaa gtgccagttt      360

ttccacaaag agcggatgga ggtgtgtgag aatcaccagc actggcacac ggtagtcaaa      420

gaggcatgtc tgactcaggg aatgacctta tatagctacg gcatgctgct cccatgtggg      480

gtagaccagt tccatggcac tgaatatgtg tgctgccctc agacaaagat tattggatct      540

gtgtcaaaag aagaggaaga ggaagatgaa gaggaagagg aagaggaaga tgaagaggaa      600

gactatgatg tttataaaag tgaatttcct actgaagcag atctggaaga cttcacagaa      660

gcagctgtgg atgaggatga tgaggatgag gaagaagggg aggaagtggt ggaggaccga      720

gattactact atgacacctt caaaggagat gactacaatg aggagaatcc tactgaaccc      780

ggcagcgacg gcaccatgtc agacaaggaa attactcatg atgtcaaagc tgtctgctcc      840

caggaggcga tgacggggcc ctgccgggcc gtgatgcctc gttggtactt cgacctctcc      900

aagggaaagt gcgtgcgctt tatatatggt ggctgcggcg gcaacaggaa caattttgag      960

tctgaggatt attgtatggc tgtgtgtaaa gcgatgattc ctccaactcc tctgccaacc     1020

aatgatgttg atgtgtattt cgagacctct gcagatgata atgagcatgc tcgcttccag     1080

aaggctaagg agcagctgga gattcggcac cgcaaccgaa tggacagggt aaagaaggaa     1140

tgggaagagg cagagcttca agctaagaac ctccccaaag cagagaggca gactctgatt     1200

cagcacttcc aagccatggt taaagcttta gagaaggaag cagccagtga gaagcagcag     1260

ctggtggaga cccacctggc ccgagtggaa gctatgctga atgaccgccg tcggatggct     1320

ctggagaact acctggctgc cttgcagtct gacccgccac ggcctcatcg cattctccag     1380

gccttacggc gttatgtccg tgctgagaac aaagatcgct tacataccat ccgtcattac     1440

cagcatgtgt tggctgttga cccagaaaag gcggcccaga tgaaatccca ggtgatgaca     1500

catctccacg tgattgaaga aaggaggaac caaagcctct ctctgctcta caaagtacct     1560

tatgtagccc aagaaattca agaggaaatt gatgagctcc ttcaggagca gcgtgcagat     1620

atggaccagt tcactgcctc aatctcagag acccctgtgg acgtccgggt gagctctgag     1680

gagagtgagg agatcccacc gttccacccc ttccacccct tcccagccct acctgagaac     1740

gaaggatctg gagtgggaga gcaggatggg ggactgatcg gtgccgaaga gaaagtgatt     1800

aacagtaaga ataaagtgga tgaaaacatg gtcattgacg agactctgga tgttaaggaa     1860

atgattttca atgccgagag agttggaggc ctcgaggaag agcgggaatc cgtgggccca     1920

ctgcgggagg acttcagtct gagtagc                                         1947


<210>  5452
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5452
cccatcatca tgggctccaa catcggcacc tctgtcacca acaccatcgt ggccctgatg       60

caggcggggg acaggactga cttccggcgg gccttcgcgg gggccacggt gcatgactgc      120

tttaactggc tgtcagtgct ggtcctgctg cccctggagg ctgccactgg ctacctgcac      180

cacatcactc gacttgtggt ggcctccttc aacatccatg gtggccgtga tgctcctgac      240

ctgctcaaga tcatcacaga gcccttcacg aagctcatca tccagctgga cgagtctgtg      300

ataaccagca ttgccactgg tgatgagtcc ctgaggaacc acagtctcat ccagatctgg      360

tgccacccag actccttaca ggctcccacc tccatgtcca gagcagaggc caactccagc      420

cagacccttg gaaatgccac catggagaaa tgcaaccaca tctttgtgga cactggccta      480

ccggac                                                                 486


<210>  5453
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5453
ctgaacgagg aggagcggct gatccggcac ctgtttcaag agaagggcta caacaaggag       60

ctccggcccg tggcacacaa agaggagagt gtggacgttg ccctggccct cacactctcc      120

aacctcatct ccctgaaaga agttgaggag accctcacta ccaatgtgtg gatagagcac      180

ggctggacag acaaccggct gaagtggaat gctgaagaat ttggaaacat cagtgtcctg      240

cgcctccccc cggacatggt gtggctccca gagattgtgc tggagaacaa caatgacggc      300

tccttccaga tctcctactc ctgcaacgtg cttgtctacc actacggctt cgtgtactgg      360

ctgccacctg ccatcttccg ctcctcctgc cccatctctg tcacctattt ccccttcgac      420

tggcagaact gctccctcaa gttcagttcc ctcaagtata cggccaaaga gatcaccctg      480

agcctgaaac aggatgccaa ggagaaccgc acctaccccg tggagtggat catcattgat      540

cctgaaggct tcacagagaa cggggagtgg gagatagtcc accggccggc cagggtcaac      600

gtggacccca gagcccctct ggacagcccc agccgccagg acatcacctt ctacctcatc      660

atccgccgca ag                                                          672


<210>  5454
<211>  627
<212>  DNA
<213>  Homo Sapiens

<400>  5454
ctgcacaccg acggagacaa agcttttgtt gatttcctga gtgatgaaat taaggaggaa       60

agaaaaattc agaagcataa aaccctccct aagatgtctg gaggttggga gctggaactg      120

aatgggacag aagcgaaatt agtgcggaaa gttgccgggg aaaaaatcac ggtcactttc      180

aacattaaca acagcatccc accaacattt gatggtgagg aggaaccctc gcaagggcag      240

aaggttgaag aacaggagcc tgaactgaca tcaactccca atttcgtggt tgaagttata      300

aagaatgatg atggcaagaa ggcccttgtg ttggactgtc attatccaga ggatgaggtt      360

ggacaagaag acgaggctga gagtgacatc ttctctatca gggaagttag ctttcagtcc      420

actggcgagt ctgaatggaa ggatactaat tatacactca acacagattc cttggactgg      480

gccttatatg accacctaat ggatttcctt gccgaccgag gggtggacaa cacttttgca      540

gatgagctgg tggagctcag cacagccctg gagcaccagg agtacattac ttttcttgaa      600

gacctcaaga gttttgtcaa gagccag                                          627


<210>  5455
<211>  2754
<212>  DNA
<213>  Homo Sapiens

<400>  5455
accagatcgt gtgactccag cggggacggc gggccgggca ctgcgccagc tccttcccac       60

ctgccttctt ccacggccag cccctcaggt cctcctgccc aggaccagga catctgcccg      120

gccagtgagg atgagagcgg acagtggaaa aactttcgac tgccggactt cgtcaaccca      180

gtccactacg acctgcacgt gaagcccctg ttggaggagg acacctacac gggcaccgtg      240

agcatctcca tcaacctgag cgctcccacc cggtacctgt ggctgcacct ccgggagacc      300

aggatcaccc ggctcccgga gctgaagagg ccctctgggg accaggtgca agtccggagg      360

tgtttcgagt acaaaaagca ggagtacgtg gtggtcgagg cggaggaaga gcttaccccc      420

agcagtggag atggcctgta tctcctgacc atggagttcg ccggctggct gaacggctcc      480

ctcgtgggat tttatagaac cacctacacg gagaacggac gagtcaagag catagtggcc      540

accgatcatg aaccaacaga tgccaggaaa tcttttcctt gttttgatga gcccaacaaa      600

aaggcaactt atacaatatc tatcacccat cccaaagaat acggagcact ttcaaatatg      660

ccagtggcga aagaagagtc agtggatgat aaatggactc gaacaacttt tgagaagtct      720

gtccccatga gcacgtacct ggtgtgcttt gctgtacatc aatttgactc tgtaaagaga      780

atatcaaata gtggaaaacc tcttacaatt tatgtccagc cagagcaaaa gcacacagcc      840

gaatatgctg caaacataac taaaagtgtg tttgattatt ttgaagaata ctttgctatg      900

aattattctc ttcctaaatt agataaaatc gctattccag attttggcac tggtgccatg      960

gagaactggg gactcatcac gtacagagaa acgaacctgc tttatgaccc taaggaatca     1020

gcctcatcaa accaacagag ggtggccact gtggttgccc atgaacttgt gcatcagtgg     1080

tttggaaata ttgtgaccat ggactggtgg gaagacttgt ggctaaatga aggatttgct     1140

tctttctttg agtttctggg agtaaaccat gcagaaacag actggcaaat gcgtgaccaa     1200

atgttacttg aagatgtatt acctgttcaa gaggatgatt ctttgatgtc ttcgcatcca     1260

attattgtga ctgtgacaac ccctgatgaa ataacatctg tttttgatgg aatatcctat     1320

agcaagggat cttctatttt gagaatgctt gaagactgga taaaaccaga gaattttcaa     1380

aaaggatgtc agatgtactt ggaaaaatac caattcaaga atgcaaaaac ttctgatttt     1440

tgggcagcac tggaagaggc aagtaggcta ccagtgaaag aagtaatgga cacctggacc     1500

agacagatgg gttatcctgt gcttaacgtg aacggtgtca agaacatcac acagaaacgc     1560

tttttgttgg acccaagagc taacccttct cagccccctt cagatcttgg ttatacatgg     1620

aatatcccag ttaaatggac tgaagataat ataacaagca gtgtgttatt taataggtca     1680

gaaaaagaag gaatcacttt gaactcctct aatcctagtg gaaatgcttt tctcaaaata     1740

aacccagatc atattgggtt ttatcgtgta aattatgaag tagcaacttg ggactcgata     1800

gctacagcgc tctccttgaa ccacaagaca ttttcttcag cagatcgtgc aagtcttatt     1860

gatgatgctt ttgccttggc aagagctcaa cttctagatt ataaggtggc tttgaacttg     1920

accaagtatc tcaaaaggga agagaatttt ttaccatggc agagagtaat ttcagctgta     1980

acctacatca ttagcatgtt tgaagatgat aaagagctat atcctatgat tgaggaatac     2040

ttccaaggtc aagtgaagcc tattgcagat tctctgggat ggaatgatgc tggagaccat     2100

gtcacaaagt tactccgttc ctccgtgtta gggtttgcgt gcaagatggg agacagagaa     2160

gccttgaaca atgcttcctc gttatttgag cagtggctaa atgggactgt aagccttccc     2220

gtaaatctca ggcttctggt gtatcggtat gggatgcaga actctggcaa tgagatttca     2280

tggaactaca ctcttgagca ataccagaaa acttcattag ctcaagaaaa agaaaaactg     2340

ctgtatggat tagcatcagt gaagaacgtt actcttttgt caaggtattt ggatttgctc     2400

aaggacacga accttattaa aactcaggat gtgtttacag tcattcgata tatctcatat     2460

aacagctatg ggaagaacat ggcctggaat tggatacaac tcaactggga ctatctagtc     2520

aacagatata cactcaataa cagaaacctt ggccgaattg tcacaatagc agagccattc     2580

aacactgaac tgcaactgtg gcagatggag agcttttttg caaaatatcc acaagctgga     2640

gcaggagaaa aacctaggga acaagtgctg gaaacagtga aaaacaatat agagtggcta     2700

aaacaacata gaaacaccat cagagaatgg ttttttaatt tacttgagag tggt           2754


<210>  5456
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5456
cagtatggcg attatggata cccataccag cagtatcatg actacagcga tgatgggtgg       60

gtgaatttga accggcaagg cttcagctac cagtgtcccc aggggcaggt gatagtggcc      120

gtgaggagca tcttcagcaa gaaggaaggt tctgacagac aatggaacta cgcctgcatg      180

cccacaccac agagcctcgg ggaacccacg gagtgctggt gggaggagat caacagggct      240

ggcatggaat ggtaccagac gtgctccaac aatgggctgg tggcaggatt ccagagccgc      300

tacttcgagt cagtgctgga tcgggagtgg cagttttact gttgtcgcta cagcaagagg      360

tgcccatatt cctgctggct aacaatagaa tatccaggtc actatggtga ggaaatggac      420

atgatttcct acaattatga ttactatatc cgaggagcaa caaccacttt ctctgcagtg      480

gaaagggatc gccagtggaa gttcataatg tgccggatga ctgaatacga ctgtgaattt      540

gcaaatgtt                                                              549


<210>  5457
<211>  1731
<212>  DNA
<213>  Homo Sapiens

<400>  5457
gccctctctc caaagtgcct agactggtgg caggaggggc ccatgtacca gatctaccca       60

aggtctttca aggacagtaa caaggatggg aacggagatc tgaaaggtat tcaagataaa      120

ctggactaca tcacagcttt aaatataaaa actgtttgga ttacttcatt ttataaatcg      180

tcccttaaag atttcagata tggtgttgaa gatttccggg aagttgatcc catttttgga      240

acgatggaag attttgagaa tctggttgca gccatacatg ataaaggttt aaaattaatc      300

atcgatttca taccaaacca cacgagtgat aaacatattt ggtttcaatt gagtcggaca      360

cggacaggaa aatatactga ttattatatc tggcatgact gtacccatga aaatggcaaa      420

accattccac ccaacaactg gttaagtgtg tatggaaact ccagttggca ctttgacgaa      480

gtgcgaaacc aatgttattt tcatcagttt atgaaagagc aacctgattt aaatttccgc      540

aatcctgatg ttcaagaaga aataaaagaa attttacggt tctggctcac aaagggtgtt      600

gatggtttta gtttggatgc tgttaaattc ctcctagaag caaagcacct gagagatgag      660

atccaagtaa ataagaccca aatcccggac acggtcacac aatactcgga gctgtaccat      720

gacttcacca ccacgcaggt gggaatgcac gacattgtcc gcagcttccg gcagaccatg      780

gaccaataca gcacggagcc cggcagatac aggttcatgg ggactgaagc ctatgcagag      840

agtattgaca ggaccgtgat gtactatgga ttgccattta tccaagaagc tgattttccc      900

ttcaacaatt acctcagcat gctagacact gtttctggga acagcgtgta tgaggttatc      960

acatcctgga tggaaaacat gccagaagga aaatggccta actggatgat tggtggacca     1020

gacagttcac ggctgacttc gcgtttgggg aatcagtatg tcaacgtgat gaacatgctt     1080

cttttcacac tccctggaac tcctataact tactatggag aagaaattgg aatgggaaat     1140

attgtagccg caaatctcaa tgaaagctat gatattaata cccttcgctc aaagtcacca     1200

atgcagtggg acaatagttc aaatgctggt ttttctgaag ctagtaacac ctggttacct     1260

accaattcag attaccacac tgtgaatgtt gatgtccaaa agactcagcc cagatcggct     1320

ttgaagttat atcaagattt aagtctactt catgccaatg agctactcct caacaggggc     1380

tggttttgcc atttgaggaa tgacagccac tatgttgtgt acacaagaga gctggatggc     1440

atcgacagaa tctttatcgt ggttctgaat tttggagaat caacactgtt aaatctacat     1500

aatatgattt cgggccttcc cgctaaaata agaataaggt taagtaccaa ttctgccgac     1560

aaaggcagta aagttgatac aagtggcatt tttctggaca agggagaggg actcatcttt     1620

gaacacaaca cgaagaatct ccttcatcgc caaacagctt tcagagatag atgctttgtt     1680

tccaatcgag catgctattc cagtgtactg aacatactgt atacctcgtg t              1731


<210>  5458
<211>  1191
<212>  DNA
<213>  Homo Sapiens

<400>  5458
gacatgaagg gacattttga tcctgccaag tgccgctatg ccctgggcat gcaggaccgg       60

accatcccag acagtgacat ctctgcttcc agctcctggt cagattccac tgccgcccgc      120

cacagcaggt tggagagcag tgacggggat ggggcctggt gccccgcagg gtcggtgttt      180

cccaaggagg aggagtactt gcaggtggat ctacaacgac tgcacctggt ggctctggtg      240

ggcacccagg gacggcatgc cgggggcctg ggcaaggagt tctcccggag ctaccggctg      300

cgttactccc gggatggtcg ccgctggatg ggctggaagg accgctgggg tcaggaggtg      360

atctcaggca atgaggaccc tgagggagtg gtgctgaagg accttgggcc ccccatggtt      420

gcccgactgg ttcacttcta cccccgggct gaccgggtca tgagcgtctg tctgcgggta      480

gagctctatg gctgcctctg gagggatgga ctcctgtctt acaccgcccc tgtggggcag      540

acaatgtatt tatctgaggc cgtgtacctc aacgactcca cctatgacgg acataccgtg      600

ggcggactgc agtatggggg tctgggccag ctggcagatg gtgtggtggg gctggatgac      660

tttaggaaga gtcaggagct gcgggtctgg ccaggctatg actatgtggg atggagcaac      720

cacagcttct ccagtggcta tgtggagatg gagtttgagt ttgaccggct gagggccttc      780

caggctatgc aggtccactg taacaacatg cacacgctgg gagcccgtct gcctggcggg      840

gtggaatgtc gcttccggcg tggccctgcc atggcctggg agggggagcc catgcgccac      900

aacctagggg gcaacctggg ggaccccaga gcccgggctg tctcagtgcc ccttggcggc      960

cgtgtggctc gctttctgca gtgccgcttc ctctttgcgg ggccctggtt actcttcagc     1020

gaaatctcct tcatctctga tgtggtgaac aattcctctc cggcactggg aggcaccttc     1080

ccgccagccc cctggtggcc gcctggccca cctcccacca acttcagcag cttggagctg     1140

gagcccagag gccagcagcc cgtggccaag gccgagggga gcccgaccgc c              1191


<210>  5459
<211>  1701
<212>  DNA
<213>  Homo Sapiens

<400>  5459
gtgaacgatg gtgacatgcg gctggccgat gggggcgcca ccaaccaggg ccgcgtggag       60

atcttctaca gaggccagtg gggcactgtg tgtgacaacc tgtgggacct gactgatgcc      120

agcgtcgtct gccgggccct gggcttcgag aacgccaccc aggctctggg cagagctgcc      180

ttcgggcaag gatcaggccc catcatgctg gatgaggtcc agtgcacggg aaccgaggcc      240

tcactggccg actgcaagtc cctgggctgg ctgaagagca actgcaggca cgagagagac      300

gctggtgtgg tctgcaccaa tgaaaccagg agcacccaca ccctggacct ctccagggag      360

ctctcggagg cccttggcca gatctttgac agccagcggg gctgcgacct gtccatcagc      420

gtgaatgtgc agggcgagga cgccctgggc ttctgtggcc acacggtcat cctgactgcc      480

aacctggagg cccaggccct gtggaaggag ccgggcagca atgtcaccat gagtgtggat      540

gctgagtgtg tgcccatggt cagggacctt ctcaggtact tctactcccg aaggattgac      600

atcaccctgt cgtcagtcaa gtgcttccac aagctggcct ctgcctatgg ggccaggcag      660

ctgcagggct actgcgcaag cctctttgcc atcctcctcc cccaggaccc ctcgttccag      720

atgcccctgg acctgtatgc ctatgcagtg gccacagggg acgccctgct ggagaagctc      780

tgcctacagt tcctggcctg gaacttcgag gccttgacgc aggccgaggc ctggcccagt      840

gtccccacag acctgctcca actgctgctg cccaggagcg acctggcggt gcccagcgag      900

ctggccctac tgaaggccgt ggacacctgg agctgggggg agcgtgcctc ccatgaggag      960

gtggagggct tggtggagaa gatccgcttc cccatgatgc tccctgagga gctctttgag     1020

ctgcagttca acctgtccct gtactggagc cacgaggccc tgttccagaa gaagactctg     1080

caggccctgg aattccacac tgtgcccttc cagttgctgg cccggtacaa aggcctgaac     1140

ctcaccgagg atacctacaa gccccggatt tacacctcgc ccacctggag tgcctttgtg     1200

acagacagtt cctggagtgc acggaagtca caactggtct atcagtccag acgggggcct     1260

ttggtcaaat attcttctga ttacttccaa gccccctctg actacagata ctacccctac     1320

cagtccttcc agactccaca acaccccagc ttcctcttcc aggacaagag ggtgtcctgg     1380

tccctggtct acctccccac catccagagc tgctggaact acggcttctc ctgctcctcg     1440

gacgagctcc ctgtcctggg cctcaccaag tctggcggct cagatcgcac cattgcctac     1500

gaaaacaaag ccctgatgct ctgcgaaggg ctcttcgtgg cagacgtcac cgatttcgag     1560

ggctggaagg ctgcgattcc cagtgccctg gacaccaaca gctcgaagag cacctcctcc     1620

ttcccctgcc cggcagggca cttcaacggc ttccgcacgg tcatccgccc cttctacctg     1680

accaactcct caggtgtgga c                                               1701


<210>  5460
<211>  1671
<212>  DNA
<213>  Homo Sapiens

<400>  5460
cgatgggctc ctattccagc ttcattgatg gagaactcgt tgggtccatt tccacaacac       60

gttcagcaga tccaatctga tgctgcacag aattacacca tcttttattc cataagtggg      120

ccaggcgtgg acaaagaacc cttcaatttg ttttacatag agaaagacac tggggatatc      180

ttttgtacaa ggagcattga ccgtgagaaa tacgaacagt ttgcgttata tggctatgca      240

acaactgcag atggctatgc accagaatat ccactccctt tgatcatcaa aattgaagat      300

gataatgata acgccccata ttttgaacac agagtgacta tctttactgt gcctgaaaat      360

tgccgatccg gaacttcagt gggaaaagtg accgccacag accttgacga acctgacact      420

ctccatactc gtctgaaata taaaatctta caacaaatcc cagatcatcc aaagcatttc      480

tccatacacc cagataccgg tgtcatcacc acaactacac cttttctgga tagagaaaaa      540

tgtgatactt accagttaat aatggaagtg cgagacatgg gtggtcagcc tttcggttta      600

tttaatacag gaacaattac tatttcactt gaggatgaaa atgacaatcc accatctttc      660

acagaaactt cttatgttac agaagtagaa gaaaacagaa ttgacgtgga gattttgcga      720

atgaaggtac aggatcagga tttgccaaac actcctcact caaaggctgt atacaaaatc      780

ttacaaggaa atgaaaatgg aaacttcata attagcacag atccaaatac aaatgaagga      840

gtgctgtgtg ttgtcaagcc attgaactat gaagtcaatc gccaagttat tttgcaagtt      900

ggtgtcatta acgaggcaca attctctaaa gcagcgagct cacaaactcc tacaatgtgc      960

actacaactg tcaccgttaa aattatagac agtgatgagg gccctgaatg ccaccctcca     1020

gtgaaagtta ttcagagtca agatggcttc ccagctggcc aagaactcct tggatacaaa     1080

gcactggacc cggaaatatc cagtggtgaa ggcttaaggt atcagaagtt aggggatgaa     1140

gataactggt ttgaaattaa tcaacacact ggcgacttga gaactctaaa agtactagat     1200

agagaatcca aatttgtaaa aaacaaccaa tacaatattt cagttgttgc agtggatgca     1260

gttggccgat cttgcactgg aacattagta gttcatttgg atgattacaa cgatcacgca     1320

cctcaaattg acaaagaagt gaccatttgt cagaataatg aggattttgc tgttctgaaa     1380

cctgtagatc cagatggacc tgaaaatgga ccaccttttc aattctttct ggataattct     1440

gccagtaaaa actggaacat agaagaaaag gatggtaaaa ctgccattct tcgtcaacgg     1500

caaaatcttg attataacta ttattctgtg cctattcaaa taaaagacag gcatggttta     1560

gttgcaacac atatgttaac agtgagagta tgtgactgtt caactccatc tgagtgtaga     1620

atgaaggata aaagtacaag agacgttaga ccaaatgtaa tacttggaag a              1671


<210>  5461
<211>  1254
<212>  DNA
<213>  Homo Sapiens

<400>  5461
cggcacctgg acgcgctcgc cggaggcgcg ggccccaacc acggcaattt cctagacaat       60

gaccagtggc tgagcaccgt ctcccagtac gaccgggaca agtactggaa ccgctttcga      120

gacgatgatt atttcagaaa ctggaatccc aacaagccct ttgacaaagc cctggaccca      180

tccaaggacc cctgcctgaa ggtaaaatgc agccctcaca aagtgtgtgt gacccaggac      240

taccagaccg ccctgtgtgt cagccgcaag cacctgctcc ccaggcaaaa gaaggggaac      300

gtggcccaga aacactgggt tggaccttcg aatttggtca agtgcaagcc ctgtcccgtg      360

gcacagtcag ccatggtctg cggctcagat ggccactcct acacatccaa gtgcaaattg      420

gagttccatg cttgttctac tggcaaaagc ctcgccaccc tctgtgatgg gccctgtccc      480

tgtctcccag agcctgagcc accaaagcac aaggcagaaa ggagtgcctg cacagacaag      540

gagttgcgga accttgcctc ccggctgaag gattggtttg gagctctcca cgaggatgcg      600

aacagagtca tcaagcccac cagctccaac acagcccaag gcaggtttga cactagcatc      660

ctgcccatct gcaaggactc cctgggctgg atgttcaaca agttggacat gaactatgac      720

ctcctgcttg acccttcaga gatcaatgcc atctacctgg ataagtacga gccctgtatc      780

aagcctcttt tcaactcgtg tgactccttc aaggatggca agctttctaa caatgagtgg      840

tgctactgct tccagaagcc tggaggtctc ccttgccaga atgaaatgaa cagaattcag      900

aagctgagta aggggaaaag cctgttgggg gccttcatac ctcggtgtaa tgaggagggc      960

tattacaaag ccacacagtg ccacggcagc acggggcagt gctggtgtgt ggacaaatat     1020

gggaatgagt tggctggctc caggaaacag ggtgctgtga gctgtgaaga ggagcaggaa     1080

acctcagggg attttggcag tggtgggtcc gtggtcctgc tggatgacct agaatatgaa     1140

cgggagctgg gaccaaagga caaagagggg aagctgaggg tgcacacccg agccgtgaca     1200

gaggatgatg aggatgagga tgatgacaaa gaggatgagg tcgggtacat atgg           1254


<210>  5462
<211>  870
<212>  DNA
<213>  Homo Sapiens

<400>  5462
ctcgaggact gtgcccagga gcagatgcgg ctcagagccc aggtgcgcct gcttgagacc       60

cgggtcaaac agcaacaggt caagatcaag cagcttttgc aggagaatga agtccagttc      120

cttgataaag gagatgagaa tactgtcatt gatcttggaa gcaagaggca gtatgcagat      180

tgttcagaga ttttcaatga tgggtataag ctcagtggat tttacaaaat caaacctctc      240

cagagcccag cagaattttc tgtttattgt gacatgtccg atggaggagg atggactgta      300

attcagagac gatctgatgg cagtgaaaac tttaacagag gatggaaaga ctatgaaaat      360

ggctttggaa attttgtcca aaaacatggt gaatattggc tgggcaataa aaatcttcac      420

ttcttgacca ctcaagaaga ctacacttta aaaatcgacc ttgcagattt tgaaaaaaat      480

agccgttatg cacaatataa gaatttcaaa gttggagatg aaaagaattt ctacgagttg      540

aatattgggg aatattctgg aacagctgga gattcccttg cggggaattt tcatcctgag      600

gtgcagtggt gggctagtca ccaaagaatg aaattcagca cgtgggacag agatcatgac      660

aactatgaag ggaactgcgc agaagaagat cagtctggct ggtggtttaa caggtgtcac      720

tctgcaaacc tgaatggtgt atactacagc ggcccctaca cggctaaaac agacaatggg      780

attgtctggt acacctggca tgggtggtgg tattctctga aatctgtggt tatgaaaatt      840

aggccaaatg attttattcc aaatgtaatt                                       870


<210>  5463
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  5463
gagacctccc cgattttgac agagaagcag gccaaacagc tcctaagatc tcggcgacag       60

gatagaccaa gcaaacccgg attccccgat gagccaatgc gggaatacat gcaccacctg      120

ctcgccctgg agcatcgcgc tgaggagcag ttcctggagc actggctgaa ccctcactgc      180

aaaccccact gtgacaggaa caggattcat cctgtg                                216


<210>  5464
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  5464
gcctgccccg cctccgccga cctcaagcac tcggacggga cgcgcacttg cgccaagctc       60

tatgacaaga gcgaccccta ctatgagaac tgctgcgggg gcgccgagct gtcgctggag      120

tcgggcgcag acctgcccta cctgccctcc aactgggcca acaccgcctc ctcacttgtg      180

gtggccccgc gctgcgagct caccgtgtgg tcccggcaag gcaaggcggg caagacgcac      240

aagttctctg ccggcaccta cccgcgcctg gaggagtacc gccggggcat cttaggagac      300

tggtccaacg ctatctccgc gctctactgc aggtgcagc                             339


<210>  5465
<211>  795
<212>  DNA
<213>  Homo Sapiens

<400>  5465
ggggcgcgcg cgcggtggcg cggggagggc accagcgcac acttgcggga catcttcctg       60

ggccgctgcg ccgagtaccg cgcactgctg agtcccgagc agcggaacaa gaactgcaca      120

gccatctggg aagcctttaa agtggcgctg gacaaggatc cctgctccgt gctcccctca      180

gactatgacc tttttattaa cttgtccagg cactctattc ccagagataa gtccctgttc      240

tgggaaaata gccacctcct tgttaacagc tttgcagaca acacccgtcg ttttatgccc      300

ctgagcgatg ttctgtatgg cagggttgca gatttcttga gctggtgtcg acagaaaaat      360

gactctggac tcgattacca atcctgccct acatcagaag actgtgaaaa taatcctgtg      420

gattcctttt ggaaaagggc atccatccag tattccaagg atagttctgg ggtgatccac      480

gtcatgctga atggttcaga gccaacagga gcctatccca tcaaaggttt ttttgcagat      540

tatgaaattc caaacctcca gaaggaaaaa attacacgaa tcgagatctg ggttatgcat      600

gaaattgggg gacccaatgt ggaatcctgc ggggaaggca gcatgaaagt cctggaaaag      660

aggctgaagg acatggggtt ccagtacagc tgtattaatg attaccgacc agtgaagctc      720

ttacagtgcg tggaccacag cacccatcct gactgtgcct taaagtcggc agcagccgct      780

actcaaagaa aagcc                                                       795


<210>  5466
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  5466
aacagcgagg cctgccggga cggccttcgg gcagtgatgg agtgtcgcaa tgtcacccat       60

ctcctgcaac aagagctgac cgaggcccag aagggctttc aggatgtgga ggcccaggcc      120

gccacctgca accacactgt gatggcccta atggcttccc tggatgcaga gaaggcccaa      180

ggacaaaaga aagtggagga gcttgaggga gagatcacta cattaaacca taagcttcag      240

gacgcgtctg cagaggtgga gcgactgaga agagaaaacc aggtcttaag cgtgagaatc      300

gcggacaaga agtactaccc cagctcccag gactccagc                             339


<210>  5467
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  5467
gaggaagagc taaggagcaa atccaagatc tgtgccaatg tgttttgtgg agccggccgg       60

gaatgtgcag tcacagagaa aggggaaccc acctgtctct gcattgagca atgcaaacct      120

cacaagaggc ctgtgtgtgg cagtaatggc aagacctacc tcaaccactg tgaactgcat      180

cgagatgcct gcctcactgg atccaaaatc caggttgatt acgatggaca ctgcaaagag      240

aagaaatccg taagtccatc tgccagccca gttgtttgct atcagtccaa ccgtgatgag      300

ctccgacgtc gcatcatcca gtggctggaa gctgagatca ttccagatgg ctggttctct      360

aaaggcagca actacagtga aatcctagac aagtatttta agaactttga taatggtgat      420

tctcgcctgg actccagtga attcctgaag tttgtggaac agaatgaaac tgccatcaat      480

attacaacgt atccagacca ggagaacaac aagttgctta ggggactctg tgttgatgct      540

ctcattgaac tgtctgatga aaatgctgat tggaaactca gcttccaaga gtttctcaag      600

tgcctcaacc catctttcaa ccctcctgag aagaagtgtg ccctggagga tgaaacgtat      660

gcagatggag ctgagaccga ggtggactgt aaccgctgtg tctgtgcctg tggaaattgg      720

gtctgtacag ccatgacctg tgacggaaag aatcagaagg gggcccagac ccagacagag      780

gaggagatga ccagatatgt ccaggagctc caaaagcatc aggaaacagc tgaaaagacc      840

aagagagtga gcaccaaaga gatc                                             864


<210>  5468
<211>  2205
<212>  DNA
<213>  Homo Sapiens

<400>  5468
ttacgccctt caagagttca taactctgaa gaaaatacaa tgagagcact cacactgaag       60

gatattttaa atggaacatt ttcttataaa acattttttc caaactggat ttcaggacaa      120

gaatatcttc atcaatctgc agataacaat atagtacttt ataatattga aacaggacaa      180

tcatatacca ttttgagtaa tagaaccatg aaaagtgtga atgcttcaaa ttacggctta      240

tcacctgatc ggcaatttgt atatctagaa agtgattatt caaagctttg gagatactct      300

tacacagcaa catattacat ctatgacctt agcaatggag aatttgtaag aggaaatgag      360

cttcctcgtc caattcagta tttatgctgg tcgcctgttg ggagtaaatt agcatatgtc      420

tatcaaaaca atatctattt gaaacaaaga ccaggagatc caccttttca aataacattt      480

aatggaagag aaaataaaat atttaatgga atcccagact gggtttatga agaggaaatg      540

cttgctacaa aatatgctct ctggtggtct cctaatggaa aatttttggc atatgcggaa      600

tttaatgata cggatatacc agttattgcc tattcctatt atggcgatga acaatatcct      660

agaacaataa atattccata cccaaaggct ggagctaaga atcccgttgt tcggatattt      720

attatcgata ccacttaccc tgcgtatgta ggtccccagg aagtgcctgt tccagcaatg      780

atagcctcaa gtgattatta tttcagttgg ctcacgtggg ttactgatga acgagtatgt      840

ttgcagtggc taaaaagagt ccagaatgtt tcggtcctgt ctatatgtga cttcagggaa      900

gactggcaga catgggattg tccaaagacc caggagcata tagaagaaag cagaactgga      960

tgggctggtg gattctttgt ttcaacacca gttttcagct atgatgccat ttcgtactac     1020

aaaatattta gtgacaagga tggctacaaa catattcact atatcaaaga cactgtggaa     1080

aatgctattc aaattacaag tggcaagtgg gaggccataa atatattcag agtaacacag     1140

gattcactgt tttattctag caatgaattt gaagaatacc ctggaagaag aaacatctac     1200

agaattagca ttggaagcta tcctccaagc aagaagtgtg ttacttgcca tctaaggaaa     1260

gaaaggtgcc aatattacac agcaagtttc agcgactacg ccaagtacta tgcacttgtc     1320

tgctacggcc caggcatccc catttccacc cttcatgatg gacgcactga tcaagaaatt     1380

aaaatcctgg aagaaaacaa ggaattggaa aatgctttga aaaatatcca gctgcctaaa     1440

gaggaaatta agaaacttga agtagatgaa attactttat ggtacaagat gattcttcct     1500

cctcaatttg acagatcaaa gaagtatccc ttgctaattc aagtgtatgg tggtccctgc     1560

agtcagagtg taaggtctgt atttgctgtt aattggatat cttatcttgc aagtaaggaa     1620

gggatggtca ttgccttggt ggatggtcga ggaacagctt tccaaggtga caaactcctc     1680

tatgcagtgt atcgaaagct gggtgtttat gaagttgaag accagattac agctgtcaga     1740

aaattcatag aaatgggttt cattgatgaa aaaagaatag ccatatgggg ctggtcctat     1800

ggaggatacg tttcatcact ggcccttgca tctggaactg gtcttttcaa atgtggtata     1860

gcagtggctc cagtctccag ctgggaatat tacgcgtctg tctacacaga gagattcatg     1920

ggtctcccaa caaaggatga taatcttgag cactataaga attcaactgt gatggcaaga     1980

gcagaatatt tcagaaatgt agactatctt ctcatccacg gaacagcaga tgataatgtg     2040

cactttcaaa actcagcaca gattgctaaa gctctggtta atgcacaagt ggatttccag     2100

gcaatgtggt actctgacca gaaccacggc ttatccggcc tgtccacgaa ccacttatac     2160

acccacatga cccacttcct aaagcagtgt ttctctttgt cagac                     2205


<210>  5469
<211>  1971
<212>  DNA
<213>  Homo Sapiens

<400>  5469
cataaactcg tgtgttattt caccaactgg gcacacagtc ggccaggccc tgcctcgatc       60

ttgccccatg acctggaccc ctttctctgc acccacctga tatttgcctt tgcctcaatg      120

aacaacaatc agattgttgc taaggatctc caggatgaga aaattctcta cccagagttc      180

aacaaactaa aggagaggaa cagagagctg aaaacactac tgtccatcgg cgggtggaac      240

tttggcacct caagattcac cactatgttg tccacatttg ccaaccgtga aaagtttatt      300

gcttcagtta tatcccttct gaggacacat gactttgatg gtcttgacct tttcttctta      360

tatcctggac taagaggcag ccccatgcat gaccggtgga cttttctctt cttaattgaa      420

gagctcctgt ttgccttccg gaaggaggca ctgctcacca tgcgcccgag gctgctgctg      480

tctgctgctg tttctggggt cccacacatc gtccaaacat cctatgatgt gcgctttcta      540

ggaagactcc tggatttcat caatgtcttg tcttatgact tacatggaag ttgggaaagg      600

ttcacaggac ataatagccc cctcttctct ctgcctgaag accccaaatc ttcggcatat      660

gctatgaatt attggagaaa gcttggggca ccctcagaga agctcatcat ggggatcccc      720

acctatggac gtacctttcg cctcctcaaa gcctctaaga atgggttgca ggccagagcg      780

atcggaccag catctccagg gaagtacacc aagcaagaag gcttcttggc ttattttgag      840

atttgttcct ttgtctgggg agcgaagaag cactggattg attaccagta tgtcccgtat      900

gccaacaagg ggaaagagtg ggttggctat gacaatgcca tcagcttcag ttacaaggca      960

tggtttataa ggcgagagca ttttgggggg gccatggtgt ggacattgga catggatgac     1020

gtcaggggca cgttctgtgg cactggccct ttcccccttg tctacgtatt gaatgatatc     1080

ctggtgcggg ctgagttcag ttcaacttct ttaccacaat tttggctgtc atctgctgtg     1140

aattcttcaa gcactgaccc tgaaaggctg gctgtgacca cggcatggac cactgatagt     1200

aagattttgc ccccaggagg agaggctggg gtcactgaga tccacggaaa gtgtgaaaat     1260

atgactataa cccctagagg tacaactgtg acccctacaa aggaaactgt atcccttgga     1320

aagcacactg tagctctagg agagaagact gagatcactg gggcaatgac catgacttct     1380

gtgggtcatc agtccatgac ccctggagag aaggccctga cccctgtggg tcatcaatct     1440

gtgaccactg gacagaagac cctgacctct gtgggttatc agtctgtgac ccctggggaa     1500

aagaccctga cccctgtggg tcatcagtct gtgacccctg tgagtcatca gtctgtgagc     1560

cctggaggaa cgactatgac ccctgtccat tttcagactg agacccttag acagaataca     1620

gtggccccta gaaggaaggc tgtggcccgt gaaaaggtga ctgtcccctc cagaaacata     1680

tcagtcaccc ctgaagggca gactatgcct ttaagagggg agaatttgac ttctgaggtg     1740

ggcactcacc ccaggatggg taacttgggt cttcagatgg aagctgaaaa caggatgatg     1800

ctgtcctcca gccccgtcat ccagctcccg gaacaaactc ctctagcttt tgacaaccgc     1860

tttgttccca tctatggaaa ccattcctct gtcaactcag taacccctca aacaagtcct     1920

ctttctctaa aaaaagaaat cccagaaaac tctgctgtgg atgaagaagc c              1971


<210>  5470
<211>  498
<212>  DNA
<213>  Homo Sapiens

<400>  5470
tctaagccaa tagatgtttc ccgtctggat cttcgaattg gttgcatcat aactgctaga       60

aaacaccctg atgcagattc tttgtatgtg gaagaagtag atgtcggaga aatagcccca      120

aggacagttg tcagtggcct ggtgaatcat gttcctcttg aacagatgca aaatcggatg      180

gtgattttac tttgtaacct gaaacctgca aagatgaggg gagtattatc tcaagcaatg      240

gtcatgtgtg ctagttcacc agagaaaatt gaaatcttgg ctcctccaaa tgggtctgtt      300

cctggagaca gaattacttt tgatgctttc ccaggagagc ctgacaagga gctgaatcct      360

aagaagaaga tttgggagca gatccagcct gatcttcaca ctaatgatga gtgtgtggct      420

acatacaaag gagttccctt tgaggtgaaa gggaagggag tatgtagggc tcaaaccatg      480

agcaacagtg gaatcaaa                                                    498


<210>  5471
<211>  1596
<212>  DNA
<213>  Homo Sapiens

<400>  5471
atgccccacg tcatccggat cggaggaatc ttcgagtatg cggacggccc caacgcccag       60

gtcatgaatg ccgaggagca tgcctttcga ttttctgcca acatcatcaa caggaacagg      120

actctgctgc ccaacacaac cttgacctat gacatacaga ggattcactt ccatgacagc      180

ttcgaggcga ccaaaaaggc ctgtgaccag ctggcactgg gcgtggtggc gatcttcggc      240

ccatcacagg gctcctgcac caatgccgtc cagtccatct gcaatgccct ggaggtgccc      300

cacatccagc tgcgttggaa gcaccacccg ctggacaaca aggacacctt ctacgtgaac      360

ctctaccccg actacgcctc gctcagccat gccatcctcg acctggtcca gtacctcaag      420

tggcggtcag ccaccgtggt ctatgacgac agtacagggc tcatccgact gcaggagctc      480

atcatggccc catcaagata caacatccgc ctgaagatcc gtcagctccc catcgactct      540

gacgactcgc gccccttgct caaggagatg aagcgaggcc gggaattccg cattatcttc      600

gactgcagcc acactatggc ggcccagatc ctcaagcagg ccatggccat gggcatgatg      660

actgagtact accacttcat cttcaccact ctggatctct acgctttaga cctggagccc      720

taccgctact caggcgtgaa cctgacagga ttccggattc tcaatgtgga caacccacac      780

gtctcggcca ttgtggagaa gtggtccatg gagcggctgc aggcagctcc ccggtccgag      840

tctggcctgc tggatggagt gatgatgact gatgcagcct tactgtacga cgccgtccat      900

atcgtgtccg tgtgctacca gcgggcacca cagatgaccg tgaactccct gcagtgccat      960

cggcacaagg cctggcgctt tggcggccgc ttcatgaact tcatcaagga ggctcaatgg     1020

gaaggattaa ctggacgaat tgttttcaac aaaactagtg gcttgcggac ggattttgat     1080

ctggacatca tcagcctgaa agaggatggc ctggagaagg ttggggtgtg gagtcctgcc     1140

gacgggctca acatcactga ggttgccaaa ggccgaggcc ctaatgtcac cgactctctg     1200

acaaacagat cactcattgt caccacagtg ctggaggagc ccttcgtcat gtttcggaaa     1260

tcagacagga cgctatacgg gaatgaccgg ttcgagggct actgcatcga cctgctaaag     1320

gagctggccc acatccttgg tttctcctat gagatccggc tggtggagga cggcaagtac     1380

ggggcacagg atgacaaggg ccagtggaac ggcatggtca aggagctcat cgaccacaag     1440

gcagatctgg ccgtggcccc cctgaccatc acccatgttc gagagaaggc catcgacttc     1500

tccaagccct tcatgacact tggtgtgagc atcctgtatc gaaagcccaa tggcaccaac     1560

cccagcgtct tctccttcct caatcccctg tcccca                               1596


<210>  5472
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  5472
caggaacagg gagcgaggag cccctcggag gagcctccag aggaggaaat ccccaaggag       60

gatgggatct tggtgctgag ccgccacacc ctgggcctgg ccctgcggga gcaccctgcc      120

ctgctggtgg aattctatgc cccgtggtgt gggcactgcc aggccctggc ccccgagtac      180

agcaaggcag ctgccgtgct cgcggccgag tcaatggtgg tcacgctggc caaggtggat      240

gggcccgcgc agcgcgagct ggctgaggag tttggtgtga cggagtaccc tacgctcaag      300

ttcttccgca atgggaaccg cacgcacccg gaggagtaca caggaccacg ggacgctgag      360

ggcattgccg agtggctgcg acggcgggtg gggcccagtg ccatgcggct ggaggacgag      420

gcggccgccc aggcgctgat cggtggccgg gacctagtgg tcattggctt cttccaggac      480

ctgcaggacg aggacgtggc caccttcttg gccttggccc aggacgccct ggacatgacc      540

tttggcctca cagaccggcc gcggctcttt cagcagtttg gcctcaccaa ggacactgtg      600

gttctcttca agaagtttga tgaggggcgg gcagacttcc ccgtggacga ggagcttggc      660

ctggacctgg gggatctgtc gcgcttcctg gtcacacaca gcatgcgcct ggtcacggag      720

ttcaacagcc agacgtctgc caagatcttc gcggccagga tcctcaacca cctgctgctg      780

tttgtcaacc agacgctggc tgcgcaccgg gagctcctag cgggctttgg ggaggcagct      840

ccccgcttcc gggggcaggt gctgttcgtg gtggtggacg tggcggccga caatgagcac      900

gtgctgcagt actttggact caaggctgag gcagccccca ctctgcgctt ggtcaacctt      960

gaaaccacta agaagtatgc gcctgtggat gggggccctg tcaccgcagc gtccatcact     1020

gctttctgcc atgcagtcct caacggccaa gtcaagccct atctcctgag ccaggagata     1080

ccccctgatt gggatcagcg gccagttaag accctcgtgg gcaagaattt tgagcaggtg     1140

gcttttgacg aaaccaagaa tgtgtttgtc aagttctatg ccccgtggtg cacccactgc     1200

aaggagatgg cccctgcctg ggaggcattg gctgagaagt accaagacca cgaggacatc     1260

atcattgctg agctggatgc cacggccaac gagctggatg ccttcgctgt gcacggcttc     1320

cctactctca agtacttccc agcagggcca ggtcggaagg tgattgaata caaaagcacc     1380

agggacctgg agactttctc caagttcctg gacaacgggg gcgtgctgcc cacggaggag     1440

cccccggagg agccagcagc cccgttcccg gagccaccgg ccaactccac tatggggtcc     1500


<210>  5473
<211>  1260
<212>  DNA
<213>  Homo Sapiens

<400>  5473
tttgactggc aatacataaa tcctgttgcc catatgaaat catcagcatg ggtcaacaaa       60

atacaagtac tgatggctgc tgcaagcttt ggccaaacta aaatcccccg gggaaatggg      120

ccttattccg ttggttgtac agacttaatg tttgatcaca ctaataaggg caccttcttg      180

cgtttatatt atccatccca agataatgat cgccttgaca ccctttggat cccaaataaa      240

gaatattttt ggggtcttag caaatttctt ggaacacact ggcttatggg caacattttg      300

aggttactct ttggttcaat gacaactcct gcaaactgga attcccctct gaggcctggt      360

gaaaaatatc cacttgttgt tttttctcat ggtcttgggg cattcaggac actttattct      420

gctattggca ttgacctggc atctcatggg tttatagttg ctgctgtaga acacagagat      480

agatctgcat ctgcaactta ctatttcaag gaccaatctg ctgcagaaat aggggacaag      540

tcttggctct accttagaac cctgaaacaa gaggaggaga cacatatacg aaatgagcag      600

gtacggcaaa gagcaaaaga atgttcccaa gctctcagtc tgattcttga cattgatcat      660

ggaaagccag tgaagaatgc attagattta aagtttgata tggaacaact gaaggactct      720

attgataggg aaaaaatagc agtaattgga cattcttttg gtggagcaac ggttattcag      780

actcttagtg aagatcagag attcagatgt ggtattgccc tggatgcatg gatgtttcca      840

ctgggtgatg aagtatattc cagaattcct cagcccctct tttttatcaa ctctgaatat      900

ttccaatatc ctgctaatat cataaaaatg aaaaaatgct actcacctga taaagaaaga      960

aagatgatta caatcagggg ttcagtccac cagaattttg ctgacttcac ttttgcaact     1020

ggcaaaataa ttggacacat gctcaaatta aagggagaca tagattcaaa tgcagctatt     1080

gatcttagca acaaagcttc attagcattc ttacaaaagc atttaggact tcataaagat     1140

tttgatcagt gggactgctt gattgaagga gatgatgaga atcttattcc agggaccaac     1200

attaacacaa ccaatcaaca catcatgtta cagaactctt caggaataga gaaatacaat     1260


<210>  5474
<211>  396
<212>  DNA
<213>  Homo Sapiens

<400>  5474
gtgctgctca ccaaaggtga aattcgatgc tactgtgatg ctgcccactg tgtagccact       60

ggttatatgt gtaaatctga gctcagcgcc tgcttctcta gacttcttga tcctcagaac      120

tcaaattccc cactcaccca tggctgcctg gactctcttg caagcacgac agacatctgc      180

caagccaaac aggcccgaaa ccactctggc accaccatac ccacattgga atgctgtcat      240

gaagacatgt gcaattacag agggctgcac gatgttctct ctcctcccag gggtgaggcc      300

tcaggacaag gaaacaggta tcagcatgat ggtagcagaa accttatcac caaggtgcag      360

gagctgactt cttccaaaga gttgtggttc cgggca                                396


<210>  5475
<211>  702
<212>  DNA
<213>  Homo Sapiens

<400>  5475
tgggagacag aggagaggcc ccggactcgc gaagaggagt gccacttcta cgcgggtgga       60

caagtgtacc cgggagaggc atcccgggta tcggtcgccg accactccct gcacctaagc      120

aaagcgaaga tttccaagcc agcgccctac tgggaaggaa cagctgtgat cgatggagaa      180

tttaaggagc tgaagttaac tgattatcgt gggaaatact tggttttctt cttctaccca      240

cttgatttca catttgtgtg tccaactgaa attatcgctt ttggcgacag acttgaagaa      300

ttcagatcta taaatactga agtggtagca tgctctgttg attcacagtt tacccatttg      360

gcctggatta atacccctcg aagacaagga ggacttgggc caataaggat tccacttctt      420

tcagatttga cccatcagat ctcaaaggac tatggtgtat acctagagga ctcaggccac      480

actcttagag gtctcttcat tattgatgac aaaggaatcc taagacaaat tactctgaat      540

gatcttcctg tgggtagatc agtggatgag acactacgtt tggttcaagc attccagtac      600

actgacaaac acggagaagt ctgccctgct ggctggaaac ctggtagtga aacaataatc      660

ccagatccag ctggaaagct gaagtatttc gataaactga at                         702


<210>  5476
<211>  1419
<212>  DNA
<213>  Homo Sapiens

<400>  5476
ggagtaaatg cagatgttga gaaacatctt gaattgggca agaaattact tgcagctgga       60

cagctagctg atgctttatc tcagtttcat gctgccgtag atggtgaccc tgataactat      120

attgcttatt atcggagggc tactgtcttt ttagctatgg gcaaatcaaa agctgcactt      180

cctgatttaa ctaaagtgat tcaattgaag atggacttca ctgcagcaag attacagaga      240

ggtcacttat tactcaaaca aggaaaactt gatgaagcag aagatgattt taaaaaagtg      300

ctcaaatcta atccaagtga aaatgaagaa aaggaagcac agtctcaact tataaaatct      360

gatgaaatgc agcgtttgcg ttcacaagca cttaacgctt ttggaagtgg agattatact      420

gctgctatag ccttccttga taagatttta gaggtttgtg tttgggatgc agaactacgg      480

gaacttcgag ctgaatgttt tataaaagaa ggagaaccta ggaaagctat aagtgactta      540

aaagctgcgt caaagttgaa gaatgataat actgaagcgt tttataaaat aagcacactg      600

tactaccaac taggagacca cgaactgtcc ctcagtgaag ttcgggaatg tcttaaactt      660

gaccaggatc ataaaaggtg ttttgcacac tataaacaag taaagaaact taataagctg      720

attgagtcag ctgaagagct catcagagat ggcagataca cagatgctac cagcaaatat      780

gaatctgtca tgaaaacaga gccaagcatt gctgaatata cagttcgttc aaaggagagg      840

atttgccact gcttttctaa ggacgagaag cctgttgaag ctattagggt ttgttctgaa      900

gttttacaga tggaacctga caatgtgaat gccctgaaag atcgagcaga ggcctatttg      960

atagaggaaa tgtatgatga agctattcag gattatgaaa ctgctcagga acacaatgaa     1020

aatgatcagc agattcgaga aggtctagag aaagcacaaa gattattgaa acagtcgcag     1080

aaacgagatt attataaaat cttgggagta aaaagaaatg ccaaaaagca agaaattatt     1140

aaagcatacc gaaaattagc actgcagtgg cacccagata acttccagaa tgaagaagaa     1200

aagaaaaaag ctgagaaaaa gttcattgat atagcagctg ctaaagaagt cctctctgat     1260

ccagaaatga gaaagaagtt tgacgacgga gaagatcctt tggatgcaga gagccagcaa     1320

ggaggcggcg gcaacccttt ccacagaagc tggaactcat ggcaagggtt caatcccttc     1380

agctcaggcg gaccatttag atttaaattc cacttcaat                            1419


<210>  5477
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  5477
gcaaaactgg tctgctactt caccaactgg gcccagtaca gacaggggga ggctcgcttc       60

ctgcccaagg acttggaccc cagcctttgc acccacctca tctacgcctt cgctggcatg      120

accaaccacc agctgagcac cactgagtgg aatgacgaga ctctctacca ggagttcaat      180

ggcctgaaga agatgaatcc caagctgaag accctgttag ccatcggagg ctggaatttc      240

agcactcaga agttcacaga tatggtagcc acggccaaca accgtcagac ctttgtcaac      300

tcggccatca ggtttctgcg caaatacagc tttgacggcc ttgaccttga ctgggagtac      360

ccaggaagcc aggggagccc tgccgtagac aaggagcgct tcacaaccct ggtacaggac      420

ttggccaatg ccttccagca ggaagcccag acctcaggga aggaacgcct tcttctgagt      480

gcagcggttc cagctgggca gacctatgtg gatgctggat acgaggtgga caaaatcgcc      540

cagaacctgg attttgtcaa ccttatggcc tacgacttcc atggctcttg ggagaaggtc      600

acgggacata acagccccct ctacaagagg caagaagaga gtggtgcagc agccagcctc      660

aacgtggatg ctgctgtgca acagtggctg cagaagggga cccctgccag caagctgatc      720

cttggcatgc ctacctacgg acgctccttc acactggcct cctcatcaga caccagagtg      780

ggggccccag ccacagggtc tggcactcca ggccccttca ccaaggaagg agggatgctg      840

gcctactatg aagtctgctc ctggaagggg gccaccaaac agagaatcca ggatcagaag      900

gtgccctaca tcttccggga caaccagtgg gtgggctttg atgatgtgga gagcttcaaa      960

accaaggtca gctatctgaa gcagaaggga ctgggcgggg ccatggtctg ggcactggac     1020

ttagatgact ttgccggctt ctcctgcaac cagggccgat accccctcat ccagacgcta     1080

cggcaggaac tgagtcttcc atacttgcct tcaggcaccc cagagcttga agttccaaaa     1140

ccaggtcagc cctctgaacc tgagcatggc cccagccctg gacaagacac gttctgccag     1200

ggcaaagctg atgggctcta tcccaatcct cgggaacggt ccagcttcta cagctgtgca     1260

gcggggcggc tgttccagca aagctgcccg acaggcctgg tgttcagcaa ctcctgcaaa     1320

tgctgcacct ggaat                                                      1335


<210>  5478
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  5478
cagcactatc tccacatccg cccggcaccc agcgacaacc tgcccctggt ggacctcatc       60

gaacacccag accctatctt tgaccccaag gaaaaggatc tgaacgagac gctgctgcgc      120

tcgctgctcg ggggccacta cgacccaggc ttcatggcca cctcgccccc cgaggaccgg      180

cccggcgggg gcgggggtgc agctgggggc gcggaggacc tggcggagct ggaccagctg      240

ctgcggcagc ggccgtcggg ggccatgccg agcgagatca aagggctaga gttctccgag      300

ggcttggccc agggcaagaa gcagcgccta agcaagaagc tgcggaggaa gttacagatg      360

tggctgtggt cgcagacatt ctgccccgtg ctgtacgcgt ggaacgacct gggcagccgc      420

ttttggccgc gctacgtgaa ggtgggcagc tgcttcagta agcgctcgtg ctccgtgccc      480

gagggcatgg tgtgcaagcc gtccaagtcc gtgcacctca cggtgctgcg gtggcgctgt      540

cagcggcgcg ggggccagcg ctgcggctgg attcccatcc agtaccccat catttccgag      600

tgcaagtgct cgtgc                                                       615


<210>  5479
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  5479
ggctctggct gccccttatt ggagaatgtg atttccaaga caatcaatcc acaagtgtct       60

aagactgaat acaaagaact tcttcaagag ttcatagacg acaatgccac tacaaatgcc      120

atagatgaat tgaaggaatg ttttcttaac caaacggatg aaactctgag caatgttgag      180

gtgtttatgc aattaatata tgacagcagt ctttgtgatt tattt                      225


<210>  5480
<211>  1491
<212>  DNA
<213>  Homo Sapiens

<400>  5480
ctcccagtaa ccaggtatca aaataatgaa tctgaggatt ctgaagaatg gaagggtcat       60

ttggctcagg caccaacacc acccttggag agcagtgagt catcagaagg cagtaaagtt      120

agctcagagg aacaggcaaa tgaagacccc agtgacagca ctcagtcaga ggagggcctg      180

ggctctgatg atcatcaata catttatagg ctagctggtg gcttctccag gagcacagga      240

aaaggaggag atgataaaga tgacgatgaa gatgacagtg gagatgacac ctttggtgac      300

gatgacagtg gcccagggcc caaagacaga caagaaggag gaaactccag actgggaagt      360

gatgaggact ctgatgacac catacaagcc agtgaagaga gtgccccaca agggcaagac      420

agtgcccaag ataccaccag tgagagcagg gaacttgaca atgaggaccg ggtggacagc      480

aagcctgagg gaggtgactc cactcaagag agtgagagtg aagagcactg ggtgggaggt      540

ggcagtgatg gggagagcag ccatggagac ggctccgagt tggacgatga gggaatgcag      600

agtgatgacc cagagagcat caggagtgaa aggggaaact ccagaatgaa cagtgcaggc      660

atgaaatcaa aagaatctgg agaaaacagt gagcaagcaa acactcaaga ttcaggtggc      720

agccaattgc tggagcatcc cagtaggaaa atttttagga agtctcgcat ctcagaggaa      780

gatgacagaa gcgagcttga tgacaacaac acaatggaag aagtcaagag tgactctaca      840

gaaaacagca actccagaga cactggcctc agccaaccca ggagagacag caagggtgac      900

tctcaagaag acagcaagga gaatctgtcc caggaagaga gccaaaacgt agatggtccc      960

agcagtgagt ccagccaaga ggccaacctg tcatctcaag agaacagcag tgagtctcag     1020

gaagaggtgg tgagtgagtc caggggagat aaccccgacc ccacaactag ttatgtagaa     1080

gaccaggaag acagtgactc cagcgaggag gacagctcgc acacactctc ccactcaaaa     1140

agtgaatcca gagaggagca agcagacagt gaatccagtg aaagcctcaa cttctcagag     1200

gaaagcccgg agtcccctga ggatgagaac agctccagcc aggagggcct ccagtctcac     1260

agcagctcag cagagagtca gagcgaggaa agccattctg aggaagacga cagtgactct     1320

caagacagca gcagatccaa agaagatagc aactccacgg agagcaaatc aagcagtgag     1380

gaagatggcc agttgaaaaa cattgagata gagagccgga aattaacagt tgatgcctat     1440

cacaacaaac ccattgggga ccaagatgac aatgactgcc aagacggcta t              1491


<210>  5481
<211>  456
<212>  DNA
<213>  Homo Sapiens

<400>  5481
atacccctgg gggtcaatag tcaacgagga gacgatgtga ctcaagcgac tccagaaaca       60

ttcacagaag atcctaatct ggtgaatgat cccgctacag atgaaacagt tttggctgtt      120

ttggctgata ttgcaccttc cacagatgac ttggcctccc tcagtgaaaa aaataccact      180

gcagagtgct gggatgagaa atttacctgc acaaggctct actctgtgca tcggccggtt      240

aaacaatgca ttcatcagtt atgcttcacc agtttacgac gtatgtacat cgtcaacaag      300

gagatctgct ctcgtcttgt ctgtaaggaa cacgaagcta tgaaagatga gctttgccgt      360

cagatggctg gtctgccccc taggagactc cgtcgctcca attacttccg acttcctccc      420

tgtgaaaatg tggatttgca gagacccaat ggtctg                                456


<210>  5482
<211>  909
<212>  DNA
<213>  Homo Sapiens

<400>  5482
gaagtggaga agacagcctg tccttcaggc aagaaggctc ccgagataga cgagagcctc       60

atcttctaca agaagtggga gctggaagcc tgcgtggatg cggccctgct ggccacccag      120

atggaccgcg tgaacgccat ccccttcacc tacgagcagc tggacgtcct aaagcataaa      180

ctggatgagc tctacccaca aggttacccc gagtctgtga tccagcacct gggctacctc      240

ttcctcaaga tgagccctga ggacattcgc aagtggaatg tgacgtccct ggagaccctg      300

aaggctttgc ttgaagtcaa caaagggcac gaaatgagtc ctcaggtggc caccctgatc      360

gaccgctttg tgaagggaag gggccagcta gacaaagaca ccctagacac cctgaccgcc      420

ttctaccctg ggtacctgtg ctccctcagc cccgaggagc tgagctccgt gccccccagc      480

agcatctggg cggtcaggcc ccaggacctg gacacgtgtg acccaaggca gctggacgtc      540

ctctatccca aggcccgcct tgctttccag aacatgaacg ggtccgaata cttcgtgaag      600

atccagtcct tcctgggtgg ggcccccacg gaggatttga aggcgctcag tcagcagaat      660

gtgagcatgg acttggccac gttcatgaag ctgcggacgg atgcggtgct gccgttgact      720

gtggctgagg tgcagaaact tctgggaccc cacgtggagg gcctgaaggc ggaggagcgg      780

caccgcccgg tgcgggactg gatcctacgg cagcggcagg acgacctgga cacgctgggg      840

ctggggctac agggcggcat ccccaacggc tacctggtcc tagacctcag catgcaagag      900

gccctctcg                                                              909


<210>  5483
<211>  1761
<212>  DNA
<213>  Homo Sapiens

<400>  5483
ggcggtgtcg ggagcctgaa cctggaggag ctgagtgaga tgcgttatgg gatcgagatc       60

ctgccgttgc ctgtcatggg agggcagagc caatcttcgg acgtggtgat tgtctcctct      120

aagtacaaac agcgctatga gtgtcgcctg ccagctggag ctattcactt ccagcgtgaa      180

agggaggagg aaacacctgc ttaccaaggg cctgggatcc ctgagttgtt gagcccaatg      240

agagatgctc cctgcttgct gaagacaaag gactggtgga catatgaatt ctgttatgga      300

cgccacatcc agcaatacca catggaagat tcagagatca aaggtgaagt cctctatctc      360

ggctactacc aatcagcctt cgactgggat gatgaaacag ccaaggcctc caagcagcat      420

cgtcttaaac gctaccacag ccagacctat ggcaatgggt ccaagtgcga ccttaatggg      480

aggccccggg aggccgaggt tcggttcctc tgtgacgagg gtgcaggtat ctctggggac      540

tacatcgatc gcgtggacga gcccttgtcc tgctcttatg tgctgaccat tcgcactcct      600

cggctctgcc cccaccctct cctccggccc ccacccagtg ctgcaccgca ggccatcctc      660

tgtcaccctt ccctacagcc tgaggagtac atggcctacg ttcagaggca agccgactca      720

aagcagtatg gagataaaat catagaggag ctgcaagatc taggccccca agtgtggagt      780

gagaccaagt ctggggtggc accccaaaag atggcaggtg cgagcccgac caaggatgac      840

agtaaggact cagatttctg gaagatgctt aatgagccag aggaccaggc cccaggaggg      900

gaggaggtgc cggctgagga gcaggaccca agccctgagg cagcagattc agcttctggt      960

gctcccaatg attttcagaa taacgtgcag gtcaaagtca ttcgaagccc tgcggatttg     1020

attcgattca tagaggagct gaaaggtgga acaaaaaagg ggaagccaaa tataggccaa     1080

gagcagcctg tggatgatgc tgcagaagtc cctcagaggg aaccagagaa ggaaaggggt     1140

gatccagaac ggcagagaga gatggaagaa gaggaggatg aggatgagga tgaggatgaa     1200

gatgaggatg aacggcagtt actgggagaa tttgagaagg aactggaagg gatcctgctt     1260

ccgtcagacc gagaccggct ccgttcggag gtgaaggctg gcatggagcg ggaactggaa     1320

aacatcatcc aggagacaga gaaagagctg gacccagatg ggctgaagaa ggagtcagag     1380

cgggatcggg caatgctggc tctcacatcc actctcaaca aactcatcaa aagactggag     1440

gaaaaacaga gtccagagct ggtgaagaag cacaagaaaa agagggttgt ccccaaaaag     1500

cctcccccat caccccaacc tacagggaaa attgagatca aaattgtccg cccatgggct     1560

gaagggactg aagagggtgc acgttggctg actgatgagg acacgagaaa cctcaaggag     1620

atcttcttca atatcttggt gccgggagct gaagaggccc agaaggaacg ccagcggcag     1680

aaagagctgg agagcaatta ccgccgggtg tggggctctc caggtgggga gggcacaggg     1740

gacctggacg aatttgactt c                                               1761


<210>  5484
<211>  513
<212>  DNA
<213>  Homo Sapiens

<400>  5484
gcggggcccc cgccaatcca ggacggtgag ttcacgttcc tgttgccggc ggggaggaag       60

cagtgtttct accagtccgc gccggccaac gcaagcctcg agaccgaata ccaggtgatc      120

ggaggtgctg gactggacgt ggacttcacg ctggagagcc ctcagggcgt gctgttggtc      180

agcgagtccc gcaaggctga tggggtacac acggtggagc caacggaggc cggggactac      240

aagctgtgct ttgacaactc cttcagcacc atctccgaga agctggtgtt ctttgaactg      300

atctttgaca gcctccagga tgacgaggag gtcgaaggat gggcagaggc tgtggagccc      360

gaggagatgc tggatgttaa aatggaggac atcaaggagt ccattgagac catgcggacc      420

cggctggagc gcagcatcca gatgctcacg ctactgcggg ccttcgaggc acgtgaccgc      480

aacctgcaag agggcaactt ggagcgggtc aac                                   513


<210>  5485
<211>  636
<212>  DNA
<213>  Homo Sapiens

<400>  5485
gcgtccaagg ccccggtgtg ccaggaaatc acggtgccca tgtgccgcgg catcggctac       60

aacctgacgc acatgcccaa ccagttcaac cacgacacgc aggacgaggc gggcctggag      120

gtgcaccagt tctggccgct ggtggagatc caatgctcgc cggacctgcg cttcttccta      180

tgctctatgt acacgcccat ctgtctgccc gactaccaca agccgctgcc gccctgccgc      240

tcggtgtgcg agcgcgccaa ggccggctgc tcgccgctga tgcgccagta cggcttcgcc      300

tggcccgagc gcatgagctg cgaccgcctc ccggtgctgg gccgcgacgc cgaggtcctc      360

tgcatggatt acaaccgcag cgaggccacc acggcgcccc ccaggccttt cccagccaag      420

cccacccttc caggcccgcc aggggcgccg gcctcggggg gcgaatgccc cgctgggggc      480

ccgttcgtgt gcaagtgtcg cgagcccttc gtgcccattc tgaaggagtc acacccgctc      540

tacaacaagg tgcggacggg ccaggtgccc aactgcgcgg taccctgcta ccagccgtcc      600

ttcagtgccg acgagcgcac gttcgccacc ttctgg                                636


<210>  5486
<211>  153
<212>  DNA
<213>  Homo Sapiens

<400>  5486
acagccagat tcctagcttt ccttcaggca acgaaggcac aacagtatgt ggacagttac       60

gtccaagaga gtgacctcag tgaagtgaca ctcccaccag agatacagta tttcacttat      120

gctagagata aatggctccc ttctgaccct cag                                   153


<210>  5487
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  5487
gaagtgttag acatggcaga taatgcattt gatgatgaat acctgaaatg tacggacagg       60

atggaaatta aatacgttcc ccaactgcta aaggaggaaa aagcaagcca ccagcaatta      120

gatactgtgt gggaaaatgc aaaagccaaa tgggcagccc gaaagactca aatctttctc      180

cctatgaatt ttaaggataa ccatggaata gccctgatgg catatatttc cgaagctcaa      240

gagcaaactc ccttttacca tctgttcagt gaagctgtga agatggctgg ccaatctcga      300

gaagattata tctatggctt ccagttcaaa gctttccact tttacctcac aagagccctg      360

cagttgctga gaaaaccttg tgaggccagt tccaaaactg tggtatatag aacaagccag      420

ggcacttcat ttacatttgg agggctaaac caagccaggt ttggccattt taccttggca      480

tattcagcca aacctcaggc tgctaatgac cagctcactg tgttatccat ctacacatgc      540

cttggagttg acattgaaaa ttttcttgat aaagaaagtg aaagaattac tttaatacct      600

ctgaatgagg tttttcaagt gtcacaggag ggggctggca ataaccttat ccttcaaagc      660

ataaacaaga cctgcagcca ttatgagtgt gcatttctag gtggactaaa aaccgaaaac      720

tgtattgaga acctagaata ttttcaaccc atctatgtct acaaccctgg tgagaaaaac      780

cagaagcttg aagaccatag tgagaaaaac tggaagcttg aagaccatgg tgagaaaaac      840

cagaagcttg aagaccatgg tgtgaaaatc cttgaaccca cccaaatacc tggaatgaaa      900

attccagaac cttttccact acctgaagat aaaagtcaag gaaatatcaa caatcctact      960

ccaggtccag ttcctgttcc aggtcccaaa agccatcctt ctgcatcc                  1008


<210>  5488
<211>  288
<212>  DNA
<213>  Homo Sapiens

<400>  5488
atgggggctg tgctgggtgt cttctccctc gccagctggg ttccatgcct ctgcagcggt       60

gcctcatgtt tgctgtgtag ttgctgtcct aacagtaaga attccacggt gactcgcctc      120

atttatgctt tcattctcct cctgagcact gtcgtatcct atatcatgca gagaaaagag      180

atggaaactt acttgaagaa gattcctgga ttttgtgaag ggggatttaa aatccatgag      240

gctgatataa atgcagataa agattgtgat gtgctggttg gttataaa                   288


<210>  5489
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  5489
atgagctcca atgtgtacta ctacacccgg atgatgtcac agctcttcct agacaccccc       60

gtgtccaaaa cggagaaaac taactttaaa actctgtctt ccatggaaga cttctggaag      120

ttcacagaag gctccttatt ggatgggctg tactggaaga tgcagcccag caaccagact      180

gaagctgaca accgaagttt catcttctat gagaacctgc tgttaggggt tccacgaata      240

cggcaactcc gagtcagaaa tggatcctgc tctatccccc aggacttgag agatgaaatt      300

aaagagtgct atgatgtcta ctctgtcagt agtgaagata gggctccctt tgggccccga      360

aatggaaccg cttggatcta cacaagtgaa aaagacttga atggtagtag ccactgggga      420

atcattgcaa cttatagtgg agctggctat tatctggatt tgtcaagaac aagagaggaa      480

acagctgcac aagttgctag cctcaagaaa aatgtctggc tggaccgagg aaccagggca      540

acttttattg acttctcagt gtacaacgcc aacattaacc tgttctgtgt ggtcaggtta      600

ttggttgaat tcccagcaac aggtggtgtg attccatctt ggcaatttca gcctttaaag      660

ctgatccgat atgtcacaac t                                                681


<210>  5490
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  5490
atgaggatct gctccttcaa cgtcaggtcc tttggggaaa gcaagcagga agacaagaat       60

gccatggatg tcattgtgaa ggtcatcaaa cgctgtgaca tcatactcgt gatggaaatc      120

aaggacagca acaacaggat ctgccccata ctgatggaga agctgaacag aaattcaagg      180

agaggcataa cgtacaacta tgtgattagc tctcggcttg gaagaaacac atataaagaa      240

caatatgcct ttctctacaa ggaaaagctg gtgtctgtga agaggagtta tcactaccat      300

gactatcagg atggagacgc agatgtgttt tccagggagc cctttgtggt ctggttccaa      360

tctccccaca ctgctgtcaa agacttcgtg attatccccc tgcacaccac cccagagaca      420

tccgttaagg agatcgatga gttggttgag gtctacacgg acgtgaaaca ccgctggaag      480

gcggagaatt tcattttcat gggtgacttc aatgccggct gcagctacgt ccccaagaag      540

gcctggaaga acatccgctt gaggactgac cccaggtttg tttggctgat cggggaccaa      600

gaggacacca cggtgaagaa gagcaccaac tgtgcatatg acaggattgt gcttagagga      660

caagaaatcg tcagttctgt tgttcccaag tcaaacagtg tttttgactt ccagaaagct      720

tacaagctga ctgaagagga ggccctggat gtcagcgacc actttccagt tgaatttaaa      780

ctacagtctt caagggcctt caccaacagc aaaaaatctg tcactctaag gaagaaaaca      840

aagagcaaac gctcc                                                       855


<210>  5491
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  5491
tctgggcgtg gggaggctga gacacgggag tgcatctact acaacgccaa ctgggagctg       60

gagcgcacca accagagcgg cctggagcgc tgcgaaggcg agcaggacaa gcggctgcac      120

tgctacgcct cctggcgcaa cagctctggc accatcgagc tcgtgaagaa gggctgctgg      180

ctagatgact tcaactgcta cgataggcag gagtgtgtgg ccactgagga gaacccccag      240

gtgtacttct gctgctgtga aggcaacttc tgcaacgagc gcttcactca tttgccagag      300

gctgggggcc cggaagtcac gtacgagcca cccccgacag cccccaccct gctcacg         357


<210>  5492
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5492
tccctcccga cagaggactg tgagaatgag aaggagcaag ctgtgcacaa tgtagtccag       60

ctgctgccag gagtgggaac cttctacaac ctgggcacag ctttgtatta tgctactcaa      120

aactgcctgg gcaaggccag ggaacgaggc cgagatgggg ccatagatct gggatatgac      180

cttctgatga ccatggctgg gatgtcaggg gggcctatgg gtctagcgat cagtgctgca      240

cttaaacctg cattaaggtc tggggttcag cagttgatcc agtattacca agatcagaaa      300

gacgcaaaca tctctcagcc ggagaccacc aaggagggtt tgagggccat ctcagatgtg      360

agtgacttgg aagaaacaac tactctggct tctttcatat cagaagtagt aagttcagct      420

ccctactggg ggtgggccat aatcaagagc tatgacttag atcctggggc tgggagtctt      480

gagata                                                                 486


<210>  5493
<211>  2484
<212>  DNA
<213>  Homo Sapiens

<400>  5493
gcagaaggat gggaggaagg tcctcctaca gtgctatcag actccccctg gaccaacatc       60

tccggatctt gcaagggcag gtgctttgaa cttcaagagg ctggacctcc tgattgtcgc      120

tgtgacaact tgtgtaagag ctataccagt tgctgccatg actttgatga gctgtgtttg      180

aagacagccc gtggctggga gtgtactaag gacagatgtg gagaagtcag aaatgaagaa      240

aatgcctgtc actgctcaga ggactgcttg gccaggggag actgctgtac caattaccaa      300

gtggtttgca aaggagagtc gcattgggtt gatgatgact gtgaggaaat aaaggccgca      360

gaatgccctg cagggtttgt tcgccctcca ttaatcatct tctccgtgga tggcttccgt      420

gcatcataca tgaagaaagg cagcaaagtc atgcctaata ttgaaaaact aaggtcttgt      480

ggcacacact ctccctacat gaggccggtg tacccaacta aaacctttcc taacttatac      540

actttggcca ctgggctata tccagaatca catggaattg ttggcaattc aatgtatgat      600

cctgtatttg atgccacttt tcatctgcga gggcgagaga aatttaatca tagatggtgg      660

ggaggtcaac cgctatggat tacagccacc aagcaagggg tgaaagctgg aacattcttt      720

tggtctgttg tcatccctca cgagcggaga atattaacca tattgcagtg gctcaccctg      780

ccagatcatg agaggccttc ggtctatgcc ttctattctg agcaacctga tttctctgga      840

cacaaatatg gccctttcgg ccctgagatg acaaatcctc tgagggaaat cgacaaaatt      900

gtggggcaat taatggatgg actgaaacaa ctaaaactgc atcggtgtgt caacgtcatc      960

tttgtcggag accatggaat ggaagatgtc acatgtgata gaactgagtt cttgagtaat     1020

tacctaacta atgtggatga tattacttta gtgcctggaa ctctaggaag aattcgatcc     1080

aaatttagca acaatgctaa atatgacccc aaagccatta ttgccaatct cacgtgtaaa     1140

aaaccagatc agcactttaa gccttacttg aaacagcacc ttcccaaacg tttgcactat     1200

gccaacaaca gaagaattga ggatatccat ttattggtgg aacgcagatg gcatgttgca     1260

aggaaacctt tggatgttta taagaaacca tcaggaaaat gctttttcca gggagaccac     1320

ggatttgata acaaggtcaa cagcatgcag actgtttttg taggttatgg cccaacattt     1380

aagtacaaga ctaaagtgcc tccatttgaa aacattgaac tttacaatgt tatgtgtgat     1440

ctcctgggat tgaagccagc tcctaataat gggacccatg gaagtttgaa tcatctcctg     1500

cgcactaata ccttcaggcc aaccatgcca gaggaagtta ccagacccaa ttatccaggg     1560

attatgtacc ttcagtctga ttttgacctg ggctgcactt gtgatgataa ggtagagcca     1620

aagaacaagt tggatgaact caacaaacgg cttcatacaa aagggtctac agaagagaga     1680

cacctcctct atgggcgacc tgcagtgctt tatcggacta gatatgatat cttatatcac     1740

actgactttg aaagtggtta tagtgaaata ttcctaatgc cactctggac atcatatact     1800

gtttccaaac aggctgaggt ttccagcgtt cctgaccatc tgaccagttg cgtccggcct     1860

gatgtccgtg tttctccgag tttcagtcag aactgtttgg cctacaaaaa tgataagcag     1920

atgtcctacg gattcctctt tcctccttat ctgagctctt caccagaggc taaatatgat     1980

gcattccttg taaccaatat ggttccaatg tatcctgctt tcaaacgggt ctggaattat     2040

ttccaaaggg tattggtgaa gaaatatgct tcggaaagaa atggagttaa cgtgataagt     2100

ggaccaatct tcgactatga ctatgatggc ttacatgaca cagaagacaa aataaaacag     2160

tacgtggaag gcagttccat tcctgttcca actcactact acagcatcat caccagctgt     2220

ctggatttca ctcagcctgc cgacaagtgt gacggccctc tctctgtgtc ctccttcatc     2280

ctgcctcacc ggcctgacaa cgaggagagc tgcaatagct cagaggacga atcaaaatgg     2340

gtagaagaac tcatgaagat gcacacagct agggtgcgtg acattgaaca tctcaccagc     2400

ctggacttct tccgaaagac cagccgcagc tacccagaaa tcctgacact caagacatac     2460

ctgcatacat atgagagcga gatt                                            2484


<210>  5494
<211>  1977
<212>  DNA
<213>  Homo Sapiens

<400>  5494
cagagagtgg gactccccgg cccccccggc cccccagggc cgcccgggaa gcccggccag       60

gacggcattg acggagaagc tggtcctcca ggtctgcctg ggcccccggg accaaagggg      120

gccccaggaa agccggggaa accaggagag gctgggctgc cgggactgcc gggtgtggat      180

ggtctgactg gacgagatgg accccctgga cccaagggtg cccctgggga acggggaagt      240

ctgggacccc cggggccgcc cgggctgggg ggcaaaggcc tccctggacc ccccggagag      300

gcaggagtga gcggcccccc aggtgggatc ggcctccgcg gccccccggg accttctgga      360

ctccccggcc tccctggtcc cccaggacct cccggacccc ctggacaccc aggagtcctc      420

cctgaaggcg ctactgacct tcagtgccca agtatctgcc cgccaggtcc cccagggccc      480

cctggaatgc cagggttcaa gggacccact ggctacaaag gcgagcaggg ggaagtcggc      540

aaggacggcg agaagggtga ccctggcccc cctgggcccg ccggcctccc gggcagcgtg      600

gggctgcagg gcccccgggg attacgagga ctgccagggc cactcgggcc ccctggggac      660

cggggtccca ttgggttccg agggccgcct gggatcccag gagcgcctgg gaaagcgggt      720

gaccgaggcg agaggggccc agaagggttc cgcggcccca agggtgacct cggcagacct      780

ggtcccaagg gaacccccgg agtggccggg ccaagcggag agccgggcat gccgggcaag      840

gacggccaga atggcgtgcc aggactcgat ggccagaagg gagaggctgg tcgcaacggt      900

gctccgggag agaagggccc caacgggctg ccgggcctcc ctggacgagc ggggtccaaa      960

ggcgagaagg gagaacgggg cagagctggg gagctgggtg aggccggccc ctctggagag     1020

ccaggcgtcc ctggagatgc tggcatgcct ggggagcgcg gtgaggctgg ccaccggggc     1080

tcagcggggg ccctcggccc acaaggccct cccggagccc ctggtgtccg aggcttccag     1140

ggccagaagg gcagcatggg agaccccggc cttccaggcc cccagggcct ccgaggtgac     1200

gtgggcgacc ggggtccggg aggtgccgca ggccctaagg gagaccaggg tattgcaggt     1260

tccgacggtc ttcctgggga taaaggagaa ctgggtccca gcggcctggt cggacccaaa     1320

ggagagtctg gcagtcgagg ggagctgggc cccaaaggca cccagggtcc caacggcacc     1380

agcggtgttc agggtgtccc cgggcccccc ggtcctctgg gcctgcaggg cgtcccgggt     1440

gttcctggca tcacggggaa gccgggagtt ccggggaagg aggccagcga gcagcgcatc     1500

agggagctgt gtggggggat gatcagcgaa caaattgcac agttagccgc gcacctaagg     1560

aagcctttgg cacccgggtc cattggtcgg cccggtccag ctggcccccc tgggccccca     1620

ggacccccag gctccattgg tcaccctggc gctcgaggac cccccggata ccgcggtccc     1680

actggggagc tgggagaccc cgggcccaga ggaaaccagg gtgacagagg agacaaaggc     1740

gcggcaggag cagggctgga cgggcctgaa ggagaccagg ggccccaagg accccaaggc     1800

gtgcccggca ccagcaagga cggccaggac ggtgctcccg gcgagcctgg gcctcccgga     1860

gatcctgggc ttccaggtgc cattggggcc caggggacac cggggatctg cgacacctca     1920

gcctgccaag gagccgtgtt aggaggggtc ggggagaaat caggctctcg aagctca        1977


<210>  5495
<211>  879
<212>  DNA
<213>  Homo Sapiens

<400>  5495
ttgcagctgt gggacacctg ggcagatgaa gccgagaaag ccttgggtcc cctgcttgcc       60

cgggaccgga gacaggccac cgaatatgag tacctagatt atgatttcct gccagaaacg      120

gagcctccag aaatgctgag gaacagcact gacaccactc ctctgactgg gcctggaacc      180

cctgagtcta ccactgtgga gcctgctgca aggcgttcta ctggcctgga tgcaggaggg      240

gcagtcacag agctgaccac ggagctggcc aacatgggga acctgtccac ggattcagca      300

gctatggaga tacagaccac tcaaccagca gccacggagg cacagaccac tccactggca      360

gccacagagg cacagacaac tcgactgacg gccacggagg cacagaccac tccactggca      420

gccacagagg cacagaccac tccaccagca gccacggaag cacagaccac tcaacccaca      480

ggcctggagg cacagaccac tgcaccagca gccatggagg cacagaccac tgcaccagca      540

gccatggaag cacagaccac tccaccagca gccatggagg cacagaccac tcaaaccaca      600

gccatggagg cacagaccac tgcaccagaa gccacggagg cacagaccac tcaacccaca      660

gccacggagg cacagaccac tccactggca gccatggagg ccctgtccac agaacccagt      720

gccacagagg ccctgtccat ggaacctact accaaaagag gtctgttcat acccttttct      780

gtgtcctctg ttactcacaa gggcattccc atggcagcca gcaatttgtc cgtcaactac      840

ccagtggggg ccccagacca catctctgtg aagcagtgc                             879


<210>  5496
<211>  885
<212>  DNA
<213>  Homo Sapiens

<400>  5496
ggcaaggccg aggagctgca ctacccgctg ggcgagcgcc gcagcgacta cgaccgcgag       60

gcgctgctgg gcgtccagga agatgtggat gaatatgtta aactcggcca cgaagagcag      120

caaaaaagac tgcaggcgat cataaagaaa atcgacttgg actcagatgg ctttctcact      180

gaaagtgaac tcagttcatg gattcagatg tcttttaagc attatgctat gcaagaagca      240

aaacaacagt ttgttgaata tgataaaaac agtgatgata ctgtgacttg ggatgaatat      300

aacattcaga tgtatgatcg tgtgattgac tttgatgaga acactgctct ggatgatgca      360

gaagaggagt cctttaggaa gcttcactta aaggacaaga agcgatttga aaaagctaac      420

caggattcag gtcccggttt gagtcttgaa gaatttattg cttttgagca tcctgaagaa      480

gttgattata tgacggaatt tgtcattcaa gaagctttag aagaacatga caaaaatggt      540

gatggatttg ttagtttgga agaatttctt ggtgattaca ggtgggatcc aactgcaaat      600

gaagatccag aatggatact tgttgagaaa gacagattcg tgaatgatta tgacaaagat      660

aacgatggca ggcttgatcc ccaagagctg ttaccttggg tagtacctaa taatcagggc      720

attgcacaag aggaggcact tcatctaatt gatgaaatgg atttgaatgg tgacaaaaag      780

ctctctgaag aagagattct ggaaaacccg gacttgtttc tcaccagtga agccacagat      840

tatggcagac agctccatga tgactatttc tatcatgatg agctt                      885


<210>  5497
<211>  1248
<212>  DNA
<213>  Homo Sapiens

<400>  5497
aacaatgaaa cagaggaaat taaagatgaa agagcaaagg atgtctgccc agtgagacta       60

gaaagcagag ggaaatgcga agaggcaggg gagtgcccct accaggtaag cctgcccccc      120

ttgactattc agctcccgaa gcaattcagc aggatcgagg aggtgttcaa agaagtccaa      180

aacctcaagg aaatcgtaaa tagtctaaag aaatcttgcc aagactgcaa gctgcaggct      240

gatgacaacg gagacccagg cagaaacgga ctgttgttac ccagtacagg agccccggga      300

gaggttggtg ataacagagt tagagaatta gagagtgagg ttaacaagct gtcctctgag      360

ctaaagaatg ccaaagagga gatcaatgta cttcatggtc gcctggagaa gctgaatctt      420

gtaaatatga acaacataga aaattatgtt gacagcaaag tggcaaatct aacatttgtt      480

gtcaatagtt tggatggcaa atgttcaaag tgtcccagcc aagaacaaat acagtcacgt      540

ccagttcaac atctaatata taaagattgc tctgactact acgcaatagg caaaagaagc      600

agtgagacct acagagttac acctgatccc aaaaatagta gctttgaagt ttactgtgac      660

atggagacca tggggggagg ctggacagtg ctgcaggcac gtctcgatgg gagcaccaac      720

ttcaccagaa catggcaaga ctacaaagca ggctttggaa acctcagaag ggaattttgg      780

ctggggaacg ataaaattca tcttctgacc aagagtaagg aaatgattct gagaatagat      840

cttgaagact ttaatggtgt cgaactatat gccttgtatg atcagtttta tgtggctaat      900

gagtttctca aatatcgttt acacgttggt aactataatg gcacagctgg agatgcatta      960

cgtttcaaca aacattacaa ccacgatctg aagtttttca ccactccaga taaagacaat     1020

gatcgatatc cttctgggaa ctgtgggctg tactacagtt caggctggtg gtttgatgca     1080

tgtctttctg caaacttaaa tggcaaatat tatcaccaaa aatacagagg tgtccgtaat     1140

gggattttct ggggtacctg gcctggtgta agtgaggcac accctggtgg ctacaagtcc     1200

tccttcaaag aggctaagat gatgatcaga cccaagcact ttaagcca                  1248


<210>  5498
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5498
gtccaaaccg ttccgttatc caggcttttt gaccacgcta tgctccaagc ccatcgcgcg       60

caccagctgg ccattgacac ctaccaggag tttgaagaaa cctatatccc aaaggaccag      120

aagtattcat tcctgcatga ctcccagacc tccttctgct tctcagactc tattccgaca      180

ccctccaaca tggaggaaac gcaacagaaa tccaatctag agctgctccg catctccctg      240

ctgctcatcg agtcgtggct ggagcccgtg cggttcctca ggagtatgtt cgccaacaac      300

ctggtgtatg acacctcgga cagcgatgac tatcacctcc taaaggacct agaggaaggc      360

atccaaacgc tgatggggag gctggaagac ggcagccgcc ggactgggca gatcctcaag      420

cagacctaca gcaagtttga cacaaactca cacaaccatg acgcactgct caagaactac      480

gggctgctct actgcttcag gaaggacatg gacaaggtcg agacattcct gcgcatggtg      540

cagtgccgct ctgtagaggg tagctgtggc ttc                                   573


<210>  5499
<211>  366
<212>  DNA
<213>  Homo Sapiens

<400>  5499
aacaacattt actggagaga attcataaaa cttcattact taagtccaag tcgagaattc       60

aaagagtaca aatgtgatgt cctcatgaga gaaaaagagg ctctgaaagg caagagcttt      120

catatgttca tctatagctt atggttcaaa attcagcgtg catgcatcaa tgagaagggg      180

agcgaccgat atagaaatgc atatgtatgg gccccaggtg ccctcaaagt actcgagtgt      240

cactgggaga agtacaacaa taggtacaca gagagcagaa gcttcagcta cattgaattc      300

cattgtggcg tagatggata tgttgataac atagaagacc tgaggattat agaacctatc      360

agcaac                                                                 366


<210>  5500
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5500
gagaagactg gcgtgtgccc cgagctccag gctgaccaga actgcacgca agagtgcgtc       60

tcggacagcg aatgcgccga caacctcaag tgctgcagcg cgggctgtgc caccttctgc      120

tctctgccca atgataagga gggttcctgc ccccaggtga acattaactt tccccagctc      180

ggcctctgtc gggaccagtg ccaggtggac agccagtgtc ctggccagat gaaatgctgc      240

cgcaatggct gtgggaaggt gtcctgtgtc actcccaatt tc                         282


<210>  5501
<211>  1944
<212>  DNA
<213>  Homo Sapiens

<400>  5501
atcccgacaa atgcaagatt attatctgat cattccaaac caactgctga aacggtagca       60

tccgacaaca ctgcaatccc cagtttaagg gctgaagctg aagaaaatga aaaagaaaca      120

gcagtatcca cagaagacga ttcccaccat aaggctgaaa aatcatcagt actaaagtca      180

aaagaggaaa gccatgaaca gtcagcagaa cagggcaaga gttctagcca agagctggga      240

ttgaaggatc aagaggacag tgatggtcac ttaagtgtga atttggagta tgcaccaact      300

gaaggtacat cggacataaa agaagatatg agtgagcctc aggagaaaaa actctcagag      360

aacactgatt ttttggctcc tggtgttagt tccttcacag attctaacca acaagaaagt      420

atcacaaaga gagaggaaaa ccaagaacaa cctagaaatt attcacatca tcagttgaac      480

aggagcagta aacatagcca aggcctaagg gatcaaggaa accaagagca ggatccaaat      540

atttccaatg gagaagagga agaagaaaaa gagccaggtg aagttggtac ccacaatgat      600

aaccaagaaa gaaagacaga attgcccagg gagcatgcta acagcaagca ggaggaagac      660

aatacccaat ctgatgatat tttggaagag tctgatcaac caactcaagt aagcaagatg      720

caggaggatg aatttgatca gggtaaccaa gaacaagaag ataactccaa tgcagaaatg      780

gaagaggaaa atgcatcgaa cgtcaataag cacattcaag aaactgaatg gcagagtcaa      840

gagggtaaaa ctggcctaga agctatcagc aaccacaaag agacagaaga aaagactgtt      900

tctgaggctc tgctcatgga acctactgat gatggtaata ccacgcccag aaatcatgga      960

gttgatgatg atggcgatga tgatggcgat gatggcggca ctgatggccc caggcacagt     1020

gcaagtgatg actacttcat cccaagccag gcctttctgg aggccgagag agctcaatcc     1080

attgcctatc acctcaaaat tgaggagcaa agagaaaaag tacatgaaaa tgaaaatata     1140

ggtaccactg agcctggaga gcaccaagag gccaagaaag cagagaactc atcaaatgag     1200

gaggaaacgt caagtgaagg caacatgagg gtgcatgctg tggattcttg catgagcttc     1260

cagtgtaaaa gaggccacat ctgtaaggca gaccaacagg gaaaacctca ctgtgtctgc     1320

caggatccag tgacttgtcc tccaacaaaa ccccttgatc aagtttgtgg cactgacaat     1380

cagacctatg ctagttcctg tcatctattc gctactaaat gcagactgga ggggaccaaa     1440

aaggggcatc aactccagct ggattatttt ggagcctgca aatctattcc tacttgtacg     1500

gactttgaag tgattcagtt tcctctacgg atgagagact ggctcaagaa tatcctcatg     1560

cagctttatg aagccaactc tgaacacgct ggttatctaa atgaggagca gagaaataaa     1620

gtcaagaaaa tttacctgga tgaaaagagg cttttggctg gggaccatcc cattgacctt     1680

ctcttaaggg actttaagaa aaactaccac atgtatgtgt atcctgtgca ctggcagttt     1740

agtgaacttg accaacaccc tatggataga gtcttgacac attctgaact tgctcctctg     1800

cgagcatctc tggtgcccat ggaacactgc ataacccgtt tctttgagga gtgtgacccc     1860

aacaaggata agcacatcac cctgaaggag tggggccact gctttggaat taaagaagag     1920

gacatagatg aaaatctctt gttt                                            1944


<210>  5502
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  5502
gccgaaggct cgcccgggac gcccgacgag tctaccccac ctccccggaa gaagaagaag       60

gatattcgcg attacaatga tgcagacatg gcgcgtcttc tggagcaatg ggagaaagat      120

gatgacattg aagaaggaga tcttccagag cacaagagac cttcagcacc tgtcgacttc      180

tcaaagatag acccaagcaa gcctgaaagc atattgaaaa tgacgaaaaa agggaagact      240

ctcatgatgt ttgtcactgt atcaggaagc cctactgaga aggagacaga ggaaattacg      300

agcctctggc agggcagcct tttcaatgcc aactatgacg tccagaggtt cattgtggga      360

tcagaccgtg ctatcttcat gcttcgcgat gggagctacg cctgggagat caaggacttt      420

ttggtcggtc aagacaggtg tgctgatgta actctggagg gccaggtgta ccccggcaaa      480

ggaggaggaa gcaaagagaa aaataaaaca aagcaagaca agggcaaaaa aaagaaggaa      540

ggagatctga aatctcggtc ttccaaggaa gaaaatcgag ctgggaataa aagagaagac      600

ctg                                                                    603


<210>  5503
<211>  150
<212>  DNA
<213>  Homo Sapiens

<400>  5503
gcccaccact attcgcagct cacacagttt acctgtgaga ccacactcga ctcttgccag       60

tgcaaactgc cctcctcgga gccgctcagc aggacctttg tttaccggga tgtgacggac      120

tgtaccagcg tcactggcac tttcaaactg                                       150


<210>  5504
<211>  1662
<212>  DNA
<213>  Homo Sapiens

<400>  5504
ttaggggacc ataactttct aaggagagag attaaaatag aaggtgacct tgttttaggg       60

ggcctgtttc ctattaacga aaaaggcact ggaactgaag aatgtgggcg aatcaatgaa      120

gaccgaggga ttcaacgcct ggaagccatg ttgtttgcta ttgatgaaat caacaaagat      180

gattacttgc taccaggagt gaagttgggt gttcacattt tggatacatg ttcaagggat      240

acctatgcat tggagcaatc actggagttt gtcagggcat ctttgacaaa agtggatgaa      300

gctgagtata tgtgtcctga tggatcctat gccattcaag aaaacatccc acttctcatt      360

gcaggggtca ttggtggctc ttatagcagt gtttccatac aggtggcaaa cctgctgcgg      420

ctcttccaga tccctcagat cagctacgca tccaccagcg ccaaactcag tgataagtcg      480

cgctatgatt actttgccag gaccgtgccc cccgacttct accaggccaa agccatggct      540

gagatcttgc gcttcttcaa ctggacctac gtgtccacag tagcctccga gggtgattac      600

ggggagacag ggatcgaggc cttcgagcag gaagcccgcc tgcgcaacat ctgcatcgct      660

acggcggaga aggtgggccg ctccaacatc cgcaagtcct acgacagcgt gatccgagaa      720

ctgttgcaga agcccaacgc gcgcgtcgtg gtcctcttca tgcgcagcga cgactcgcgg      780

gagctcattg cagccgccag ccgcgccaat gcctccttca cctgggtggc cagcgacggc      840

tggggcgcgc aggagagcat catcaagggc agcgagcatg tggcctacgg cgccatcacc      900

ctggagctgg cctcccagcc tgtccgccag ttcgaccgct acttccagag cctcaacccc      960

tacaacaacc accgcaaccc ctggttccgg gacttctggg agcaaaagtt tcagtgcagc     1020

ctccagaaca aacgcaacca caggcgcgtc tgcgacaagc acctggccat cgacagcagc     1080

aactacgagc aagagtccaa gatcatgttt gtggtgaacg cggtgtatgc catggcccac     1140

gctttgcaca aaatgcagcg caccctctgt cccaacacta ccaagctttg tgatgctatg     1200

aagatcctgg atgggaagaa gttgtacaag gattacttgc tgaaaatcaa cttcacggct     1260

ccattcaaca caaataaaga tgcagatagc atagtcaagt ttgacacttt tggagatgga     1320

atggggcgat acaacgtgtt caatttccaa aatgtaggtg gaaagtattc ctacttgaaa     1380

gttggtcact gggcagaaac cttatcgcta gatgtcaact ctatccactg gtcccggaac     1440

tcagtcccca cttcccagtg cagcgacgcc tgtgccccca atgaaatgaa gaatatgcaa     1500

ccaggggatg tctgctgctg gatttgcatc ccctgtgaac cctacgaata cctggctgat     1560

gagtttacct gtatggattg tgggtctgga cagtggccca ctgcagacct aactggatgc     1620

tatgaccttc ctgaggacta catcaggtgg gaagacgcct gg                        1662


<210>  5505
<211>  3357
<212>  DNA
<213>  Homo Sapiens

<400>  5505
gtgaccgtta gggacaagac agaagagtca tgccctatcc tgagaataga gggacatcag       60

ctgacatatg acaacataaa caaacttgaa gtttcaggtt ttgatctagg agacagcttt      120

tctctaagac gtgcattttg tgaaagtgat aaaacctgtt tcaaattggg aagtgcactt      180

cttattagag acactattaa gatatttccc aaaggccttc ctgaggagta ctcagtagct      240

gccatgtttc gagtacgaag aaacgccaaa aaggaacggt ggtttctgtg gcaggtttta      300

aaccagcaga atattccaca gatttctata gtagttgatg gtggaaagaa ggtggtggaa      360

tttatgtttc aagccacaga gggagatgtg ttgaactaca tttttagaaa tcgagaactc      420

cgtcctttgt ttgatcgtca gtggcacaaa cttggcatta gtatacaatc ccaggtcatt      480

tcactttata tggattgtaa tttaattgcg aggaggcaga ctgatgaaaa ggacactgtg      540

gatttccatg gacggacagt tattgctacg cgagcttcag atggcaagcc tgtggatatt      600

gaacttcacc aacttaaaat ctactgcagt gcaaacctca tagctcaaga aacatgttgt      660

gaaatatcag atactaagtg cccagagcag gatggctttg gaaatattgc atcatcatgg      720

gtaactgctc atgccagtaa aatgtcttca tatctgccag caaagcagga acttaaagac      780

cagtgccagt gcattccaaa caagggagaa gcaggattac caggagctcc gggttcacct      840

gggcagaaag ggcataaagg agagccgggt gaaaatggtt tacatggtgc tccaggattc      900

cctggtcaaa agggagagca aggttttgaa ggcagcaaag gagaaactgg tgaaaagggt      960

gaacaaggag aaaaaggaga tccagctctg gctggcctta atggagaaaa tggtttgaaa     1020

ggtgacttgg gtcctcatgg tccacctggc ccaaaaggag aaaagggaga tacaggaccc     1080

ccaggaccac cagccttacc tggttccctg gggatacaag gcccccaagg tccacctgga     1140

aaagagggtc agaggggaag acgagggaaa acaggacctc ccggaaaacc aggaccccca     1200

ggaccacctg gacctcctgg aatacaagga atacaccaaa ctcttggtgg atattataac     1260

aaggataaca agggaaatga tgaacatgaa gctggaggcc tgaaaggaga caagggtgaa     1320

actggactac caggatttcc agggtctgtt ggccctaaag gacaaaaagg agaacctgga     1380

gagcctttta caaaaggaga aaaaggagat agaggagaac ctggggtaat aggatcacag     1440

ggagtaaagg gtgaacctgg agatcccgga ccccctggtt taataggaag cccaggacta     1500

aagggtcagc aaggatctgc aggctccatg ggacccagag gaccgccagg agatgttgga     1560

ttgccaggag aacatggtat cccaggaaaa caaggcatta aaggagaaaa gggagatccg     1620

ggtgggatca taggccctcc cgggcttcca ggtccaaaag gtgaggctgg tcctccaggg     1680

aaaagcctgc caggggaacc aggattagat ggaaatcctg gagcacctgg tccacgtggg     1740

ccaaagggtg aaagaggact tccaggtgtt cacggttccc caggggacat aggcccacaa     1800

gggataggaa ttcctggcag aacaggcgcc caaggaccag ctggagagcc aggtattcag     1860

ggtcctcgag gtctccctgg gttgccagga actccaggga ctccagggaa tgatggagtt     1920

ccagggagag atggaaagcc aggcctgcca ggccccccag gtgacccgat tgcacttcct     1980

ctcttgggag acatcggtgc tttgctcaag aatttctgtg gcaactgcca agccagtgtc     2040

ccagggctga aaagcaacaa aggagaagaa ggaggtgctg gtgagcctgg aaagtatgat     2100

tccatggccc ggaagggtga tatagggcca cggggtcctc caggaatccc aggaagagag     2160

ggaccaaagg gaagcaaagg agagcggggc taccctggga tacctgggga gaaaggcgat     2220

gagggtcttc aaggaattcc aggcattcca ggtgctccag gcccgactgg accccctggc     2280

ttaatgggaa gaactggaca tcctggtccc acaggagcaa aaggtgaaaa gggcagcgac     2340

ggaccccctg ggaaacccgg accacctgga ccacctggta ttccatttaa tgaacgaaac     2400

ggcatgagca gtttatataa aattaaggga ggtgtgaatg ttcccagtta cccagggcca     2460

cccggtcctc ctggcccaaa aggcgatcct ggcccagtgg gagagcctgg tgcaatgggg     2520

ttgccaggat tagaaggatt tccaggtgta aagggagatc gaggcccagc aggtccccca     2580

ggaatagcag ggatgtcggg aaaacctggt gccccagggc ctccaggagt tccaggggaa     2640

ccgggtgaga gaggacctgt tggagatata ggtttccctg gaccagaagg accctcagga     2700

aagccaggaa taaatggaaa agatggaata ccaggtgctc agggcatcat gggtaagcct     2760

ggagacagag gccccaaagg agaacgtggt gatcagggga ttccaggaga cagaggctca     2820

caaggtgaac ggggaaaacc aggccttaca ggcatgaagg gggccatcgg tcctatgggt     2880

ccaccaggaa acaagggctc catgggatcc cctggccacc aaggccctcc aggctctcca     2940

ggcatccctg gcattccggc tgatgcagtt tcatttgaag aaataaagaa gtatattaat     3000

caagaggtcc taaggatttt tgaagagagg atggctgtat tcctatccca gctcaagctg     3060

ccagcagcaa tgttggctgc ccaagcttat gggagacctg ggccaccagg gaaggatggg     3120

ttgcctgggc caccaggaga ccctggaccc caaggctaca gaggacagaa gggagaaaga     3180

ggtgaacctg gaattgggct gccagggagt ccaggtcttc ctgggacttc agctctgggt     3240

ttgccaggct caccaggtgc cccaggccca cagggccccc caggacccag tggaagatgt     3300

aacccagaag attgcctcta tcctgtgtct catgcccatc agcgcacagg tgggaat        3357


<210>  5506
<211>  2655
<212>  DNA
<213>  Homo Sapiens

<400>  5506
cgagggatcc ttgagagcat ccagaggttt tccttgctgc ccacctacct ccccgtgacc       60

taccacatca acaacgcgga cgtctccttc ttcctgaagg aggccaacca ggatatcatg      120

aggaactcca gcctgcagtc ccgggtggag tcatttctga tttacaaatc caggaggctg      180

cctgtcctca atgccagcta cgggcctttc tccatcgagc aagtggtgcc ccaggattta      240

atgctacctt ccaacccatt tggattcacc aacaaatttt ctcttaactg gaaactaaaa      300

gcccacatcc tgcgggacaa agtctacctg agccggccca aagtgcaggt tctgttccac      360

atcatgggca gagactggga cgaccgcagc gccggggaga agctgccgtg cctgagggtc      420

tttgctttcc gagagacccg agaggtgcgg ggcagctgcc ggctgcaggg ggacctgggg      480

ctgtgcgtgg ccgagctgga gctcctgtcc agctggttca gcccccccac ggtggttgcc      540

gggaggagga agtccgtgga ccagccggag gggacccccg tggagctcta ctacaccgtg      600

cacccagggg gtgagagagg ggactgcgtc agggaagacg cgaggagaag caatgggatc      660

cggacaggcc acagtgacat cgatgagtcc gggcccccct tgcagaggat cgggagcatc      720

ttcctttatc agacacacag gaaaccctcc ctgagagaac tgcgtctgga caacagcgtg      780

gccatccact atataccaaa gaccgtgagg aaaggagacg tgctgacttt tcctgtttcc      840

atctccagaa attccactga agatcgcttc acgttgaggg caaaggtgaa gaaaggcgtg      900

aacatcatcg gcgtgcgagc cagcagccct tccatttggg atgtcaagga gcgcacggat      960

tatactggaa agtatgcacc agctgtcatc gtttgtcaga agaaagcagc tggctcagaa     1020

aacagtgcgg atggcgcctc ctacgaggtc atgcagatcg atgtggaggt ggaagagcct     1080

ggtgacctgc cagccacaca gctggtcacg tggcaggtcg agtaccccgg agagatcacg     1140

tctgacttgg gagtgtccaa gatctatgtg agcccaaagg acttgattgg agttgtgccg     1200

ctggctatgg aggcagaaat cctgaacaca gccatcctca cggggaagac ggtggccgtc     1260

ccggtgaaag tggtctccgt ggaggacgac ggcacagtga cagagctgct ggagtctgtg     1320

gagtgtagat cgtctgatga agacgtgatt aaggtttctg acagatgtga ctacgtcttt     1380

gtcaatggga aagaaatgaa aggcaaggtc aacgtggtgg tgaacttcac ctaccagcac     1440

ctgagcagcc ccctggagat gacggtgtgg gtgccccggc ttccgctgca gatcgaggtc     1500

tccgacaccg agctcaatca gatcaagggt tggagagtgc ccatcgtctc cagcaggagg     1560

cctgccgggg acagtgaaga ggaggaggat gatgagcgga ggggccgcgg ctgcaccctg     1620

cagtaccagc acgccatggt gcgggtcctg acgcagtttg tggctgaggc ggccggccct     1680

gggggacacc tggcccacct gctgggctca gactggcaag tggacatcac ggagctgata     1740

aatgacttca tgcaggtgga ggagcccagg atcgccaagc tgcaaggcgg acagatcctg     1800

atggggcagg agcttgggat gaccaccatt cagatcctgt ctcctctgtc agacaccatc     1860

ctcgctgaaa agaccatcac tgtgctggac gagaaggtga ccatcacaga cctcggggtg     1920

cagctggtga cagggctgtc actctccttg cagctcagcc caggaagcaa cagggccatc     1980

tttgccactg cagtggctca ggaacttctg cagaggccaa aacaggaagc agccatcagt     2040

tgctgggtcc agttcagtga tggctcagtc acgcccttgg atatttacga tgggaaagac     2100

ttctccttga tggccacatc tttggatgag aaggtagtct ccatccacca agaccccaaa     2160

ttcaagtggc ctatcattgc tgcggaaaca gaaggacaag gcaccctggt caaggtggaa     2220

atggttatta gtgaatcctg ccagaaatcc aagcggaaga gtgtgttagc tgttggaacg     2280

gcaaacatca aagttaaatt tggccaaaac gatgctaacc ccaacaccag tgacagcaga     2340

cacacagggg caggggttca catggaaaac aatgtcagtg acagaaggcc caaaaaaccc     2400

ttgcaggaat gggggagtca ggaaggacag tactatggca gttcttctat gggactcatg     2460

gagggacggg gcaccacgac agacaggtcc atcctgcaga agaagaaagg ccaggaaagc     2520

cttttagatg acaacagcca cttgcagacc atccccagcg acctcaccag cttcccagcc     2580

caggtggacc tccccagaag caatggggaa atggatggga atgaccttat gcaggcatcc     2640

aaagggctga gcgac                                                      2655


<210>  5507
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5507
tcatccccgg gtgcaccagc tatcagcgct gcctccttcc tgcaggatct aatacatcgg       60

tatggcgagg gtgacagcct cactctgcag cagctgaagg ccctgctcaa ccacctggat      120

gtgggagtgg gccggggtaa tgtcacccag cacgtgcaag gacacaggaa cctctccacg      180

tgctttagtt ctggagacct cttcactgcc cacaatttca gcgagcagtc gcggattggg      240

agcagcgagc tccaggagtt ctgccccacc atcctccagc agctggattc ccgggcctgc      300

acctcggaga accaggaaaa cgaggagaat gagcagacgg aggaggggcg gccaagcgct      360

gttgaagtgt ggggatacgg t                                                381


<210>  5508
<211>  1788
<212>  DNA
<213>  Homo Sapiens

<400>  5508
gcggccgtgc aggcggccga ggtgaaagtg gatggcagcg agccgaaact gagcaagaat       60

gagctgaaga gacgcctgaa agctgagaag aaagtagcag agaaggaggc caaacagaag      120

gagctcagtg agaaacagct aagccaagcc actgctgctg ccaccaacca caccactgat      180

aatggtgtgg gtcctgagga agagagcgtg gacccaaatc aatactacaa aatccgcagt      240

caagcaattc atcagctgaa ggtcaatggg gaagacccat acccacacaa gttccatgta      300

gacatctcac tcactgactt catccaaaaa tatagtcacc tgcagcctgg ggatcacctg      360

actgacatca ccttaaaggt ggcaggtagg atccatgcca aaagagcttc tgggggaaag      420

ctcatcttct atgatcttcg aggagagggg gtgaagttgc aagtcatggc caattccaga      480

aattataaat cagaagaaga atttattcat attaataaca aactgcgtcg gggagacata      540

attggagttc aggggaatcc tggtaaaacc aagaagggtg agctgagcat cattccgtat      600

gagatcacac tgctgtctcc ctgtttgcat atgttacctc atcttcactt tggcctcaaa      660

gacaaggaaa caaggtatcg ccagagatac ttggacttga tcctgaatga ctttgtgagg      720

cagaaattta tcatccgctc taagatcatc acatatataa gaagtttctt agatgagctg      780

ggattcctag agattgaaac tcccatgatg aacatcatcc cagggggagc cgtggccaag      840

cctttcatca cttatcacaa cgagctggac atgaacttat atatgagaat tgctccagaa      900

ctctatcata agatgcttgt ggttggtggc atcgaccggg tttatgaaat tggacgccag      960

ttccggaatg aggggattga tttgacgcac aatcctgagt tcaccacctg tgagttctac     1020

atggcctatg cagactatca cgatctcatg gaaatcacgg agaagatggt ttcagggatg     1080

gtgaagcata ttacaggcag ttacaaggtc acctaccacc cagatggccc agagggccaa     1140

gcctacgatg ttgacttcac cccacccttc cggcgaatca acatggtaga agagcttgag     1200

aaagccctgg ggatgaagct gccagaaacg aacctctttg aaactgaaga aactcgcaaa     1260

attcttgatg atatctgtgt ggcaaaagct gttgaatgcc ctccacctcg gaccacagcc     1320

aggctccttg acaagcttgt tggggagttc ctggaagtga cttgcatcaa tcctacattc     1380

atctgtgatc acccacagat aatgagccct ttggctaaat ggcaccgctc taaagagggt     1440

ctgactgagc gctttgagct gtttgtcatg aagaaagaga tatgcaatgc gtatactgag     1500

ctgaatgatc ccatgcggca gcggcagctt tttgaagaac aggccaaggc caaggctgca     1560

ggtgatgatg aggccatgtt catagatgaa aacttctgta ctgccctgga atatgggctg     1620

ccccccacag ctggctgggg catgggcatt gatcgagtcg ccatgtttct cacggactcc     1680

aacaacatca aggaagtact tctgtttcct gccatgaaac ccgaagacaa gaaggagaat     1740

gtagcaacca ctgatacact ggaaagcaca acagttggca cttctgtc                  1788


<210>  5509
<211>  2274
<212>  DNA
<213>  Homo Sapiens

<400>  5509
aacaatcatt atgacaagat cttggctcat agtcgtatca ggggtcggga ccaaggccca       60

aatgtctgtg cccttcaaca gattttgggc accaaaaaga aatacttcag cacttgtaag      120

aactggtata aaaagtccat ctgtggacag aaaacgactg tgttatatga atgttgccct      180

ggttatatga gaatggaagg aatgaaaggc tgcccagcag ttttgcccat tgaccatgtt      240

tatggcactc tgggcatcgt gggagccacc acaacgcagc gctattctga cgcctcaaaa      300

ctgagggagg agatcgaggg aaagggatcc ttcacttact ttgcaccgag taatgaggct      360

tgggacaact tggattctga tatccgtaga ggtttggaga gcaacgtgaa tgttgaatta      420

ctgaatgctt tacatagtca catgattaat aagagaatgt tgaccaagga cttaaaaaat      480

ggcatgatta ttccttcaat gtataacaat ttggggcttt tcattaacca ttatcctaat      540

ggggttgtca ctgttaattg tgctcgaatc atccatggga accagattgc aacaaatggt      600

gttgtccatg tcattgaccg tgtgcttaca caaattggta cctcaattca agacttcatt      660

gaagcagaag atgacctttc atcttttaga gcagctgcca tcacatcgga catattggag      720

gcccttggaa gagacggtca cttcacactc tttgctccca ccaatgaggc ttttgagaaa      780

cttccacgag gtgtcctaga aaggatcatg ggagacaaag tggcttccga agctcttatg      840

aagtaccaca tcttaaatac tctccagtgt tctgagtcta ttatgggagg agcagtcttt      900

gagacgctgg aaggaaatac aattgagata ggatgtgacg gtgacagtat aacagtaaat      960

ggaatcaaaa tggtgaacaa aaaggatatt gtgacaaata atggtgtgat ccatttgatt     1020

gatcaggtcc taattcctga ttctgccaaa caagttattg agctggctgg aaaacagcaa     1080

accaccttca cggatcttgt ggcccaatta ggcttggcat ctgctctgag gccagatgga     1140

gaatacactt tgctggcacc tgtgaataat gcattttctg atgatactct cagcatggat     1200

cagcgcctcc ttaaattaat tctgcagaat cacatattga aagtaaaagt tggccttaat     1260

gagctttaca acgggcaaat actggaaacc atcggaggca aacagctcag agtcttcgta     1320

tatcgtacag ctgtctgcat tgaaaattca tgcatggaga aagggagtaa gcaagggaga     1380

aacggtgcga ttcacatatt ccgcgagatc atcaagccag cagagaaatc cctccatgaa     1440

aagttaaaac aagataagcg ctttagcacc ttcctcagcc tacttgaagc tgcagacttg     1500

aaagagctcc tgacacaacc tggagactgg acattatttg tgccaaccaa tgatgctttt     1560

aagggaatga ctagtgaaga aaaagaaatt ctgatacggg acaaaaatgc tcttcaaaac     1620

atcattcttt atcacctgac accaggagtt ttcattggaa aaggatttga acctggtgtt     1680

actaacattt taaagaccac acaaggaagc aaaatctttc tgaaagaagt aaatgataca     1740

cttctggtga atgaattgaa atcaaaagaa tctgacatca tgacaacaaa tggtgtaatt     1800

catgttgtag ataaactcct ctatccagca gacacacctg ttggaaatga tcaactgctg     1860

gaaatactta ataaattaat caaatacatc caaattaagt ttgttcgtgg tagcaccttc     1920

aaagaaatcc ccgtgactgt ctataagcca attattaaaa aatacaccaa aatcattgat     1980

ggagtgcctg tggaaataac tgaaaaagag acacgagaag aacgaatcat tacaggtcct     2040

gaaataaaat acactaggat ttctactgga ggtggagaaa cagaagaaac tctgaagaaa     2100

ttgttacaag aagaggtcac caaggtcacc aaattcattg aaggtggtga tggtcattta     2160

tttgaagatg aagaaattaa aagactgctt cagggagaca cacccgtgag gaagttgcaa     2220

gccaacaaaa aagttcaagg atctagaaga cgattaaggg aaggtcgttc tcag           2274


<210>  5510
<211>  1272
<212>  DNA
<213>  Homo Sapiens

<400>  5510
cagaccccca actacaccag acccgtgttc ctgtgcggag gggatgtgaa gggggaatca       60

ggttacgtgg caagtgaggg gttccccaac ctctaccccc ctaataagga gtgcatctgg      120

accataacgg tccccgaggg ccagactgtg tccctctcat tccgagtctt cgacctggag      180

ctgcaccccg cctgccgcta cgatgctctg gaggtcttcg ctgggtctgg gacttccggc      240

cagcggctcg gacgcttttg tgggaccttc cggcctgcgc ccctagtcgc ccccggcaac      300

caggtgaccc tgaggatgac gacggatgag ggcacaggag gacgaggctt cctgctctgg      360

tacagcgggc gggccacctc gggcactgag caccaatttt gcggggggcg gctggagaag      420

gcccagggaa ccctgaccac gcccaactgg cccgagtccg attacccccc gggcatcagc      480

tgttcctggc acatcatcgc gcccccggac caggtcatcg cgctgacctt cgagaagttt      540

gacctggagc cggacaccta ctgccgctat gactcggtca gcgtgttcaa cggagccgtg      600

agcgacgact cccggaggct ggggaagttc tgcggcgacg cagtcccggg ctccatctcc      660

tccgaaggga atgaactcct cgtccagttc gtctcagatc tcagtgtcac cgctgatggc      720

ttctcagcct cctacaagac cctgccgcgg ggcactgcca aagaagggca agggcccggc      780

cccaaacggg gaactgagcc taaagtcaag ctgcccccca agtcccaacc tccggagaaa      840

acagaggaat ctccttcagc ccctgatgca cccacctgcc caaagcagtg ccgccggaca      900

ggcaccttgc agagcaactt ctgtgccagc agccttgtgg tgactgcgac agtgaagtcc      960

atggttcggg agccagggga gggccttgcc gtgactgtca gtcttattgg tgcttataaa     1020

actggaggac tggacctgcc ttctccaccc actggtgcct ccctgaagtt ttacgtgcct     1080

tgcaagcagt gcccccccat gaagaaagga gtcagttatc tgctgatggg ccaggtagaa     1140

gagaacagag gccccgtcct tcctccagag agctttgtgg ttctccaccg gcccaaccag     1200

gaccagatcc tcaccaacct aagcaagagg aagtgcccct ctcaacctgt gcgggctgct     1260

gcgtcccagg ac                                                         1272


<210>  5511
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  5511
atggggcggc tggtggctgt gggcttgctg gggatcgcgc tggcgctcct gggcgagagg       60

cttctggcac tcagaaatcg acttaaagcc tccagagaag tagaatctgt agaccttcca      120

cactgccacc tgattaaagg aattgaagct ggctctgaag atattgacat acttcccaat      180

ggtctggctt tttttagtgt gggtctaaaa ttcccaggac tccacagctt tgcaccagat      240

aagcctggag gaatactaat gatggatcta aaagaagaaa aaccaagggc acgggaatta      300

agaatcagtc gtgggtttga tttggcctca ttcaatccac atggcatcag cactttcata      360

gacaacgatg acacagttta tctctttgtt gtaaaccacc cagaattcaa gaatacagtg      420

gaaattttta aatttgaaga agcagaaaat tctctgttgc atctgaaaac agtcaaacat      480

gagcttcttc caagtgtgaa tgacatcaca gctgttggac cggcacattt ctatgccaca      540

aatgaccact acttctctga tcctttctta aagtatttag aaacatactt gaacttacac      600

tgggcaaatg ttgtttacta cagtccaaat gaagttaaag tggtagcaga aggatttgat      660

tcagcaaatg ggatcaatat ttcacctgat gataagtata tctatgttgc tgacatattg      720

gctcatgaaa ttcatgtttt ggaaaaacac actaatatga atttaactca gttgaaggta      780

cttgagctgg atacactggt ggataattta tctattgatc cttcctcggg ggacatctgg      840

gtaggctgtc atcctaatgg ccagaagctc ttcgtgtatg acccgaacaa tcctccctcg      900

tcagaggttc tccgcatcca gaacattcta tctgagaagc ctacagtgac tacagtttat      960

gccaacaatg ggtctgttct ccaaggaagt tctgtagcct cagtgtatga tgggaagctg     1020

ctcataggca ctttatacca cagagccttg tattgtgaac tc                        1062


<210>  5512
<211>  1062
<212>  DNA
<213>  Homo Sapiens

<400>  5512
atggggaagc tcgtggcgct ggtcctgctg ggggtcggcc tgtccttagt cggggagatg       60

ttcctggcgt ttagagaaag ggtgaatgcc tctcgagaag tggagccagt agaacctgaa      120

aactgccacc ttattgagga acttgaaaat ggctctgaag atattgatat acttcctagt      180

gggctggctt ttatctccag tggattaaaa tatccaggca tgccaaactt tgcgccagat      240

gaaccaggaa aaatcttctt gatggatctg aatgaacaaa acccaagggc acaagcacta      300

gaaatcagtg gtggatttga caaagaatta tttaatccac atgggatcag tattttcatc      360

gacaaagaca atactgtgta tctttatgtt gtgaatcatc cccacatgaa gtccactgtg      420

gagatattta aatttgagga acaacaacgt tctctggtat acctgaaaac tataaaacat      480

gaacttctca aaagtgtgaa tgacattgtg gttcttggac cagaacagtt ctatgccacc      540

agagaccact attttaccaa ctccctcctg tcattttttg agatgatctt ggatcttcgc      600

tggacttatg ttcttttcta cagcccaagg gaggttaaag tggtggccaa aggattttgt      660

agtgccaatg ggatcacagt ctcagcagac cagaagtatg tctatgtagc tgatgtagca      720

gctaagaaca ttcacataat ggaaaaacat gataactggg atttaactca actgaaggtg      780

atacagttgg gcaccttagt ggataacctg actgtcgatc ctgccacagg agacattttg      840

gcaggatgcc atcctaatcc tatgaagcta ctgaactata accctgagga ccctccagga      900

tcagaagtac ttcgcatcca gaatgttttg tctgagaagc ccagggtgag caccgtgtat      960

gccaacaatg gctctgtgct tcagggcacc tctgtggctt ctgtgtacca tgggaaaatt     1020

ctcataggca ccgtatttca caaaactctg tactgtgagc tc                        1062


<210>  5513
<211>  906
<212>  DNA
<213>  Homo Sapiens

<400>  5513
aagcccacgg tgcgcaaaga gcgcgtggtg cggcccgact cggagctggg cgagcggccc       60

cctgaggaca accagagctt ccagtacgac cacgaggcct tcctgggcaa ggaggactcc      120

aagaccttcg accagctcac cccggacgag agcaaggaga ggctagggaa gattgttgat      180

cgaatcgaca atgatgggga tggctttgtc actactgagg agctgaaaac ctggatcaaa      240

cgggtgcaga aaagatacat ctttgataat gtcgccaaag tctggaagga ttatgatagg      300

gacaaggatg ataaaatttc ctgggaagaa tacaaacaag ccacctatgg ttactaccta      360

ggaaaccccg cagagtttca tgattcttca gatcatcaca cctttaaaaa gatgctgcca      420

cgtgatgaga gaagattcaa agctgcagac ctcaatggtg acctgacagc tactcgggag      480

gagttcactg cctttctgca tcctgaagag tttgaacata tgaaggaaat tgtggttttg      540

gaaaccctgg aggacatcga caagaacggg gatgggtttg tggatcagga tgagtatatt      600

gcggatatgt tttcccatga ggagaatggc cctgagccag actgggtttt atcagaacgg      660

gagcagttta acgaattccg ggatctgaac aaggacggga agttagacaa agatgagatt      720

cgccactgga tcctccctca agattatgat catgcacagg ctgaggccag gcatctggta      780

tatgaatcag acaaaaacaa ggatgagaag ctaactaaag aggaaatatt ggagaactgg      840

aacatgtttg tcggaagcca agctaccaat tacggggaag atctcacaaa aaatcatgat      900

gagctt                                                                 906


<210>  5514
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  5514
tgcggaccgg gcagggggtt cgggaagagg aggcacccca aaaagctgac ccctttagcc       60

tacaagcagt ttatccccaa tgtggccgag aagaccctag gcgccagcgg aaggtatgaa      120

gggaagatct ccagaaactc cgagcgattt aaggaactca cccccaatta caaccccgac      180

atcatattta aggatgaaga aaacaccgga gcggacaggc tgatgactca gaggtgtaag      240

gacaagttga acgctttggc catctcggtg atgaaccagt ggccaggagt gaaactgcgg      300

gtgaccgagg gctgggacga agatggccac cactcagagg agtctctgca ctacgagggc      360

cgcgcagtgg acatcaccac gtctgaccgc gaccgcagca agtacggcat gctggcccgc      420

ctggcggtgg aggccggctt cgactgggtg tactacgagt ccaaggcaca tatccactgc      480

tcggtgaaag cagagaactc ggtggcggcc aaatcgggag gctgcttccc gggctcggcc      540

acggtgcacc tggagcaggg cggcaccaag ctggtgaagg acctgagccc cggggaccgc      600

gtgctggcgg cggacgacca gggccggctg ctctacagcg acttcctcac tttcctggac      660

cgcgacgacg gcgccaagaa ggtcttctac gtgatcgaga cgcgggagcc gcgcgagcgc      720

ctgctgctca ccgccgcgca cctgctcttt gtggcgccgc acaacgactc ggccaccggg      780

gagcccgagg cgtcctcggg ctcggggccg ccttccgggg gcgcactggg gcctcgggcg      840

ctgttcgcca gccgcgtgcg cccgggccag cgcgtgtacg tggtggccga gcgtgacggg      900

gaccgccggc tcctgcccgc cgctgtgcac agcgtgaccc taagcgagga ggccgcgggc      960

gcctacgcgc cgctcacggc ccagggcacc attctcatca accgggtgct ggcctcgtgc     1020

tacgcggtca tcgaggagca cagctgggcg caccgggcct tcgcgccctt ccgcctggcg     1080

cacgcgctcc tggctgcact ggcgcccgcg cgcacggacc gcggcgggga cagcggcggc     1140

ggggaccgcg ggggcggcgg cggcagagta gccctaaccg ctccaggtgc tgccgacgct     1200

ccgggtgcgg gggccaccgc gggcatccac tggtactcgc agctgctcta ccaaataggc     1260

acctggctcc tggacagcga ggccctgcac ccgctgggca tggcggtcaa gtccagc        1317


<210>  5515
<211>  1488
<212>  DNA
<213>  Homo Sapiens

<400>  5515
aagagcattg gcaccttctc agacccctgt aaggacccca cgcgtatcac ctcccctaac       60

gacccctgcc tcactgggaa gggtgactcc agcggcttca gtagctacag tggctccagc      120

agttctggca gctccatttc cagtgccaga agctctggtg gtggctccag tggtagctcc      180

agcggatcca gcattgccca gggtggttct gcaggatctt ttaagccagg aacggggtat      240

tcccaggtca gctactcctc cggatctggc tctagtctac aaggtgcatc cggttcctcc      300

cagctgggga gcagcagctc tcactcggga agcagcggct ctcactcggg cagcagctct      360

cattcgagca gcagcagcag ctttcagttc agcagcagca gcttccaagt agggaatggc      420

tctgctctgc caaccaatga caactcttac cgcggaatac taaacccttc ccagcctgga      480

caaagctctt cctcttccca gacctttggg gtatccagca gtggccaaag cgtcagctcc      540

aaccagcgtc cctgtagttc ggacatcccc gactctccct gcagtggagg gcccatcgtc      600

tcgcactccg gcccctacat ccccagctcc cactctgtgt cagggggtca gaggcctgtg      660

gtggtggtgg tggaccagca cggttctggt gcccctggag tggttcaagg tcccccctgt      720

agcaatggtg gccttccagg caagccctgt cccccaatca cctctgtaga caaatcctat      780

ggtggctacg aggtggtggg tggctcctct gacagttatc tggttccagg catgacctac      840

agtaagggta aaatctaccc tgtgggctac ttcaccaaag agaaccctgt gaaaggctct      900

ccaggggtcc cttcctttgc agctgggccc cccatctctg agggcaaata cttctccagc      960

aaccccatca tccccagcca gtcggcagct tcctcggcca ttgcattcca gccagtgggg     1020

actggtgggg tccagctctg tggaggcggc tccacgggct ccaagggacc ctgctctccc     1080

tccagttctc gagtccccag cagttctagc atttccagca gctccggttt accctaccat     1140

ccctgcggca gtgcttccca gagcccctgc tccccaccag gcaccggctc cttcagcagc     1200

agctccagtt cccaatccag tggcaaaatc atccttcagc cttgcggcag caagtccagc     1260

tcttctggtc acccttgcat gtctgtctcc tccttgacac tgactggggg ccccgatggc     1320

tctccccatc ctgatccctc cgctggtgcc aagccctgtg gctccagcag tgctggaaag     1380

atcccctgcc gctccatccg ggatatccta gcccaagtga agcctctggg gccccagcta     1440

gctgaccctg aagttttcct accccaagga gagttactcg acagtcca                  1488


<210>  5516
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  5516
gagccattag aaaaggtggc ctctgtgggg aattctagac ccacaggcca gcagctagaa       60

tccctgggcc tcctggcccc cggggagcag agcctgccgt gcaccgagag gaagccagct      120

gctactgcca ggctgagccg tcgggggacc tcgctgtccc cgccccccga gagctccggg      180

agcccccagc agccgggcct gtccgccccc cacagccgcc agatccccgc accccagggc      240

gcggtgctgg tgcagcggga gaaggacctg ccgaactaca actggaactc cttcggcctg      300

cgcttcggca agcgggaggc ggcaccaggg aaccacggca gaagcgctgg gcggggc         357


<210>  5517
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  5517
cagccgggcg ccgcctccgc cgccatcaac gcctccgtgg gagccgcggg cagtgccgaa       60

aatgccccca gcaaggaggt gctcgattcg ttcctggatc ttgcgagaaa tatcttccct      120

tccaacctgg tgtcagcagc ctttcgctca tactctacca cctatgaaga gaggaatatc      180

accggaacca gggtgaaggt gcccgtgggg cag                                   213


<210>  5518
<211>  1092
<212>  DNA
<213>  Homo Sapiens

<400>  5518
tacaaactgg tttgctactt taccaactgg tcccaggacc ggcaggaacc aggaaaattc       60

acccctgaga atattgaccc cttcctatgc tctcatctca tctattcatt cgccagcatc      120

gaaaacaaca aggttatcat caaggacaag agtgaagtga tgctctacca gaccatcaac      180

agtctcaaaa ccaagaatcc caaactgaaa attctcttgt ccattggagg gtacctgttt      240

ggttccaaag ggttccaccc tatggtggat tcttctacat cacgcttgga attcattaac      300

tccataatcc tgtttctgag gaaccataac tttgatggac tggatgtaag ctggatctac      360

ccagatcaga aagaaaacac tcatttcact gtgctgattc atgagttagc agaagccttt      420

cagaaggact tcacaaaatc caccaaggaa aggcttctct tgactgtggg cgtatctgca      480

gggaggcaaa tgattgataa cagctatcaa gttgagaaac tggcaaaaga tctggatttc      540

atcaacctcc tgtcctttga cttccatggg tcttgggaaa agccccttat cactggccac      600

aacagccctc tgagcaaggg gtggcaggac agagggccaa gctcctacta caatgtggaa      660

tatgctgtgg ggtactggat acataaggga atgccatcag agaaggtggt catgggcatc      720

cccacatatg ggcactcctt cacactggcc tctgcagaaa ccaccgtggg ggcccctgcc      780

tctggccctg gagctgctgg acccatcaca gagtcttcag gcttcctggc ctattatgag      840

atctgccagt tcctgaaagg agccaagatc acgcggctcc aggatcagca ggttccctac      900

gcagtcaagg ggaaccagtg ggtgggctat gatgatgtga agagtatgga gaccaaggtt      960

cagttcttaa agaatttaaa cctgggagga gccatgatct ggtctattga catggatgac     1020

ttcactggca aatcctgcaa ccagggccct taccctcttg tccaagcagt caagagaagc     1080

cttggctccc tg                                                         1092


<210>  5519
<211>  1230
<212>  DNA
<213>  Homo Sapiens

<400>  5519
caggatttcg ggccgacgcg cttcatctgc acctcggtgc ccgtggacgc cgacatgtgc       60

gccgcgtccg tggccgccgg cggcgccgag gagctccgga gcagcgtgct gcagctccgc      120

gagacggtgc tgcagcagaa ggagaccatc ctgagccaga aggagaccat ccgcgagctg      180

accgccaagc tgggccgctg cgagagccag agcacgctgg accccggagc cggcgaggcc      240

cgggcgggcg gcggccgcaa gcagcccggc tcgggcaaga acaccatggg cgacctgtcc      300

cggacaccgg ccgccgagac gctcagccaa ctcgggcaaa ctttgcaatc gctcaaaacc      360

cgcctggaga acctcgagca gtacagccgc ctcaattcct ccagccagac caacagcctc      420

aaggatctgc tgcagagcaa gatcgatgag ctggagaggc aggtgctgtc ccgggtgaac      480

accctggagg agggcaaggg gggccccagg aacgacaccg aggagagggt caagatcgag      540

accgccctga cctccctgca ccagcggatc agcgagctcg agaaaggtca gaaagacaac      600

cgccctggag acaagttcca gctcacattc ccactgcgga ccaactatat gtatgccaag      660

gtgaagaaga gcctgccaga gatgtacgcc ttcactgtct gcatgtggct caagtccagc      720

gccacgccag gtgtgggcac gcccttctcc tacgctgtgc ccggccaggc caacgagctg      780

gtcctcattg agtggggcaa caaccccatg gagatcctca tcaatgacaa ggtggccaag      840

ctgccttttg tcatcaatga tggcaagtgg caccacatct gtgtcacctg gaccacccgg      900

gacggggtct gggaggccta ccaggatggc acgcagggtg gcagtggcga gaacttggcg      960

ccctatcacc ccatcaagcc ccagggcgtg ctggtgctgg gccaggagca ggacactctg     1020

ggtggtgggt ttgatgccac ccaggcattt gtgggtgagc tggcccactt caacatctgg     1080

gaccgcaagc tgacccccgg ggaggtgtac aacctggcca cctgcagcac caaggctctg     1140

tccggcaatg tcatcgcctg ggctgaatcc cacatcgaga tctacggcgg ggccaccaag     1200

tggaccttcg aggcctgtcg ccagatcaac                                      1230


<210>  5520
<211>  642
<212>  DNA
<213>  Homo Sapiens

<400>  5520
aaaggctgtg tgggctgtgc aactgaggag aggctcttcc acaaactgtt ttctcattac       60

aaccagttca tcaggcctgt ggaaaacgtt tccgaccctg tcacggtaca ctttgaagtg      120

gccatcaccc agctggccaa cgtggatgaa gtaaaccaga tcatggaaac caatttgtgg      180

ctgcgtcaca tctggaatga ttataaattg cgctgggatc caatggaata tgatggcatt      240

gagactcttc gcgttcctgc agataagatt tggaagcccg acattgttct ctataacaat      300

gctgttggtg acttccaagt agaaggcaaa acaaaagctc ttcttaaata caatggcatg      360

ataacctgga ctccaccagc tatttttaag agttcctgcc ctatggatat cacctttttc      420

ccttttgatc atcaaaactg ttccctaaaa tttggttcct ggacgtatga caaagctgaa      480

attgatcttc taatcattgg atcaaaagtg gatatgaatg atttttggga aaacagtgaa      540

tgggaaatca ttgatgcctc tggctacaaa catgacatca aatacaactg ttgtgaagag      600

atatacacag atataaccta ttctttctac attagaagat tg                         642


<210>  5521
<211>  363
<212>  DNA
<213>  Homo Sapiens

<400>  5521
cggccgcagg agcgcatggt cggagaactc cgggacctgt cgcccgacga cccgcaggtg       60

cagaaggcgg cgcaggcggc cgtggccagc tacaacatgg gcagcaacag catctactac      120

ttccgagaca cgcacatcat caaggcgcag agccagctgg tggccggcat caagtacttc      180

ctgacgatgg agatggggag cacagactgc cgcaagacca gggtcactgg agaccacgtc      240

gacctcacca cttgccccct ggcagcaggg gcgcagcagg agaagctgcg ctgtgacttt      300

gaggtccttg tggttccctg gcagaactcc tctcagctcc taaagcacaa ctgtgtgcag      360

atg                                                                    363


<210>  5522
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  5522
gaaaccacga ctcaagggcc cggagtcctg cttcccctgc ccaagggggc ctgcacaggt       60

tggatggcgg gcatcccagg gcatccgggc cataatgggg ccccaggccg tgatggcaga      120

gatggcaccc ctggtgagaa gggtgagaaa ggagatccag gtcttattgg tcctaaggga      180

gacatcggtg aaaccggagt acccggggct gaaggtcccc gaggctttcc gggaatccaa      240

ggcaggaaag gagaacctgg agaaggtgcc tatgtatacc gctcagcatt cagtgtggga      300

ttggagactt acgttactat ccccaacatg cccattcgct ttaccaagat cttctacaat      360

cagcaaaacc actatgatgg ctccactggt aaattccact gcaacattcc tgggctgtac      420

tactttgcct accacatcac agtctatatg aaggatgtga aggtcagcct cttcaagaag      480

gacaaggcta tgctcttcac ctatgatcag taccaggaaa ataatgtgga ccaggcctcc      540

ggctctgtgc tcctgcatct ggaggtgggc gaccaagtct ggctccaggt gtatggggaa      600

ggagagcgta atggactcta tgctgataat gacaatgact ccaccttcac aggctttctt      660

ctctaccatg acaccaac                                                    678


<210>  5523
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  5523
gcccagtttg tgtccagcgt gcccaggtgt gatctggtgg acttaggtga aggcaagatt       60

tgcttctgtt gtgaagaatt tcaaccagcc aagtgcacag acaaagaaaa tgccttgaaa      120

ctctttccgg ttcagccctg tagtgctgtt caccttctac ttaagaaa                   168


<210>  5524
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5524
gagcagcagg tcccgctggt gctgtggtcg agtgaccggg acttgtgggc tcctgcggcc       60

gacactcatg aaggccacat caccagcgac ttgcagctct ctacctactt agatcccgcc      120

ctggagctgg gtcccaggaa tgtgctgctg ttcctgcagg acaagctgag cattgaggat      180

ttcacagcat atggcggtgt gtttggaaac aagcaggaca gcgccttttc taacctagag      240

aatgccctgg acctggcccc ctcctcactg gtgcttcctg ccgtcgactg gtatgcagtc      300

agcactctga ccacttacct gcaggagaag ctcggggcca gccccttgca tgtggacctg      360

gccaccctgc gggagctgaa gctcaatgcc agcctccctg ctctgctgct cattcgcctg      420

ccctacacag ccagctctgg tctgatggca cccagggaag tcctcacagg caacgatgag      480

gtcatcgggc aggtcctgag cacactcaag tccgaagatg tcccatacac agcggccctc      540

acagcggtcc gcccttccag ggtggcccgt gatgtagccg tggtggccgg agggctaggt      600

cgccagctgc tacaaaaaca gccagtatca cctgtgatcc atcctcctgt gagttacaat      660

gacaccgctc cccggatcct gttctgggcc caaaacttct ctgtggcgta caaggaccag      720

tgggaggacc tgactcccct cacctttggg gtgcaggaac tcaacctgac tggctccttc      780

tggaatgact cctttgccag gctctcactg acctatgaac gactctttgg taccacagtg      840

acattcaagt tcattctggc caaccgcctc tacccagtgt ctgcccggca ctggtttacc      900

atggagcgcc tcgaagtcca cagcaatggc tccgtcgcct acttcaatgc ttcccaggtc      960

acagggccca gcatctactc cttccactgc gagtatgtca gcagcctgag caagaagggt     1020

agtctcctcg tggcccgcac gcagccctct ccctggcaga tgatgcttca ggacttccag     1080

atccaggctt tcaacgtaat gggggagcag ttctcctacg ccagcgactg tgcc           1134


<210>  5525
<211>  246
<212>  DNA
<213>  Homo Sapiens

<400>  5525
ggctccatga tctcgaatat gaatgcctca cgggcagagt tccaggccaa gattgattcc       60

atcaagcagt acatgcagtt ccgcaaggtc accaaggact tggagacgcg ggttatccgg      120

tggtttgact acctgtgggc caacaagaag acggtggatg agaaggaggt gctcaagagc      180

ctcccagaca agctgaaggc tgagatcgcc atcaacgtgc acctggacac gctgaagaag      240

gttcgc                                                                 246


<210>  5526
<211>  354
<212>  DNA
<213>  Homo Sapiens

<400>  5526
cagagcacag ataatgatgt gaactatgaa gactttactt tcaccatacc agatgtagag       60

gactcaagtc agagaccaga tcagggaccc cagagacctc ctcctgaagg actcctacct      120

agaccccctg gtgatagtgg taaccaagat gatggtcctc agcagagacc accaaaacca      180

ggaggccatc accgccatcc tcccccacct ccttttcaaa atcagcaacg accaccccaa      240

cgaggacacc gtcaactctc tctaccccga tttccttctg tcagcctgca ggaagcatca      300

tcattcttcc ggagggacag accagcaaga catccccagg agcaaccact ctgg            354


<210>  5527
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5527
aaactcgaag ttgaaggcaa cttctactca gaaaacgtca gtcggatcct ggacaacttg       60

cttgaaggct atgacaatcg gctgcggccg ggatttggag gtgctgtcac tgaagtcaaa      120

acagacattt atgtgaccag ttttgggccc gtgtcagatg tggagatgga gtatacgatg      180

gatgtttttt tccgccagac ctggactgat gagaggttga agtttggggg gccaactgag      240

attctgagtc tgaataattt gatggtcagt aaaatctgga cgcctgacac ctttttcaga      300

aatggtaaaa agtccattgc tcacaacatg acaactccta ataaactctt cagaataatg      360

cagaatggaa ccattttata caccatgagg cttaccatca atgctgactg tcccatgagg      420

ctggttaact ttcctatgga tgggcatgct tgtccactca agtttgggag ctatgcttat      480

cccaaaagtg aaatcatata tacgtggaaa aaaggaccac tttactcagt agaagtccca      540

gaagaatctt caagccttct ccagtatgat ctgattggac aaacagtatc tagtgagaca      600

attaaatcta acacaggtga atacgttata atgacagttt acttccactt gcaaaggaag      660

atgggctac                                                              669


<210>  5528
<211>  1578
<212>  DNA
<213>  Homo Sapiens

<400>  5528
agcgtccact tcaacgaccc caagtacccg cagcaatggc acctgaataa ccgacggagc       60

ccgggcaggg acatcaacgt gacgggtgtg tgggaacgca atgtgactgg gcgaggggtg      120

acggtggtgg tagtggatga cggagtggaa cacaccatcc aggacattgc acccaactat      180

agccctgagg gtagctatga cctcaactct aatgaccctg accccatgcc ccacccggat      240

gtggagaatg gcaaccacca tggcacgcga tgtgcaggag agatcgcggc tgtgcccaac      300

aacagcttct gtgccgtggg cgtggcctac gggagccgca tcgcaggtat ccgggtactg      360

gatggacctc tcacagacag catggaggca gtggcgttca acaagcacta tcagatcaat      420

gacatctaca gctgcagctg gggaccagat gacgatggga agacagtgga tggcccccat      480

cagcttggaa aggctgcctt acaacatggg gtgattgctg gtcgccaggg ctttgggagc      540

atctttgtgg tagccagtgg caacggaggc caacacaacg acaactgcaa ctacgatggc      600

tacgccaact ccatctacac cgtcaccata ggagctgtgg atgaggaggg acgcatgcct      660

ttctatgcag aagaatgtgc ctccatgctg gcagtcacct tcagtggtgg ggacaagatg      720

cttcggagca ttgtgaccac tgactgggac cttcagaagg gcactggctg cactgagggc      780

cacacaggga cctcagctgc agcgcctctg gcagctggca tgatagcctt aatgctgcag      840

gtgcggccct gcctcacgtg gcgtgacgtc cagcacatca ttgtcttcac agccacccgg      900

tatgaggatc gccgtgcaga gtgggtcacc aacgaggcag gcttcagcca tagccaccag      960

cacggtttcg gcctcctcaa cgcctggagg ctcgtgaatg cagccaagat ctggacatct     1020

gtcccttact tagcatccta cgtcagtccc gtgttaaaag aaaacaaggc gattccgcag     1080

tccccccgtt ccctggaggt cctgtggaat gtcagcagga tggacctgga gatgtcaggg     1140

ctgaagaccc tggagcatgt ggcagtgaca gtctccatca ctcacccacg gcgcggcagc     1200

ttggagctga agctgttctg ccccagtggc atgatgtccc tcatcggcgc cccccgcagc     1260

atggactcgg atcccaacgg cttcaatgac tggaccttct ccactgtgcg atgctggggg     1320

gagagagccc gagggaccta caggcttgtc atcagggatg tcggggatga gtcattccag     1380

gtcggcatcc tccggcaatg gcagctgacc ctatatggct ctgtgtggag tgcagtagac     1440

atcagggaca gacaaaggct gttagagagt gccatgagtg gaaaatacct gcacgatgac     1500

ttcgccctgc cctgcccacc ggggctgaaa attcctgagg aagatggtta caccatcacc     1560

cccaacaccc tcaagacc                                                   1578


<210>  5529
<211>  144
<212>  DNA
<213>  Homo Sapiens

<400>  5529
gttcccatct atgagaagaa gtatggccaa gtccccatgt gtgacgccgg tgagcagtgt       60

gcagtgagga aaggggcaag gatcgggaag ctgtgtgact gtccccgagg aacctcctgc      120

aattccttcc tcctgaagtg ctta                                             144


<210>  5530
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  5530
atggggaact gtctgcacag ggcggagctc tccccctcaa ctgagaactc aagtcagctg       60

gacttcgaag atgtatggaa ttcttcctat ggtgtgaatg attccttccc agatggagac      120

tatggtgcca acctggaagc agctgccccc tgccactcct gtaacctgct ggatgactct      180

gcactgccc                                                              189


<210>  5531
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  5531
tgggccgtga ttcgcattgg accaaatggc tgtgatagta tggagtttca tgaaagtggc       60

ctgcttcgat ttaagcaagt atctgacatg ggagtgatcc accctcttta taaaagcaca      120

gtaggaggaa ggcgaaatga aaatttggtc atcactggca acaaccagcc tattgttttt      180

cagcaaggga caacaaagct cagtgtagaa aacaacaaaa cttctattac aagtgacatc      240

ggcatgcagt tttttgaccc gaggactcaa aatatcttat tcagcacaga ctatgaaact      300

catgagtttc atttgccaag tggagtgaaa agtttgaatg ttcaaaaggc atctactgaa      360

aggattacca gcaatgctac cagtgattta aatataaaag ttgatgggcg tgctattgtg      420

cgtggaaatg aaggtgtatt cattatgggc aaaaccattg aatttcacat gggtggtaat      480

atggagttaa aggcggaaaa cagtatcatc ctaaatggat ctgtgatggt cagcaccacc      540

cgcctaccca gttcctccag tggagaccag ttgggtagtg gtgactgggt acgctacaag      600

ctctgcatgt gtgctgatgg gacgctcttc aaggtgcaag taaccagcca gaacatgggc      660

tgccaaatct cagacaaccc ctgtggaaac actcat                                696


<210>  5532
<211>  801
<212>  DNA
<213>  Homo Sapiens

<400>  5532
cagcagacca cgctacaccc acttgtgggc cgtgtctttg tgcacacctt ggaccatgag       60

acgtttctga gccttcctga gcatgtcgct gtcccacccg ctgtccacat cacctaccac      120

gcccacctcc agggacaccc agacctgccc cggtggctcc gctacaccca gcgcagcccc      180

caccaccctg gcttcctcta cggctctgcc accccagaag atcgtgggct ccaggtcatt      240

gaggtcacag cctacaatcg ggacagcttt gataccactc ggcagaggct ggtgctggag      300

attggggacc cagaaggccc cctgctgcca taccaagccg agttcctggt gcgcagccac      360

gatgcggagg aggtgctgcc ctcaacacct gccagccgct tcctctcagc cttgggggga      420

ctctgggagc ccggagagct tcagctgctc aacgtcacct ctgccttgga ccgtgggggc      480

cgtgtccccc ttcccattga gggccgaaaa gaaggggtat acattaaggt gggttctgcc      540

tcaccttttt ctacttgcct gaagatggtg gcatcccccg atagccacgc ccgctgtgcc      600

cagggccagc ctccacttct gtcttgctac gacaccttgg caccccactt ccgcgttgac      660

tggtgcaatg tgaccctggt ggataagtca gtgccggagc ctgcagatga ggtgcccacc      720

ccaggtgatg ggatcctgga gcatgacccg ttcttctgcc cacccactga ggccccagac      780

cgtgacttct tggtggatgc t                                                801


<210>  5533
<211>  1563
<212>  DNA
<213>  Homo Sapiens

<400>  5533
gcctctgagg gaggcttcac ggctacagga cagaggcagc tgaggccaga gcactttcaa       60

gaagttggct acgcagctcc cccctcccca cccctatccc gaagcctccc catggatcac      120

cctgactcct ctcagcatgg ccctcccttt gagggacaga gtcaagtgca gccccctccc      180

tctcaggagg ccacccctct ccaacaggaa aagctgctac ctgcccaact ccctgctgaa      240

aaggaagtgg gtccccctct ccctcaggaa gctgtccccc tccaaaaaga gctgccctct      300

ctccagcacc ccaatgaaca gaaggaagga atgccagctc catttgggga ccagagccat      360

ccagaacctg agtcctggaa tgcagcccag cactgccaac aggaccggtc ccaagggggc      420

tggggccacc ggctggatgg cttcccccct gggcggcctt ctccagacaa tctgaaccaa      480

atctgccttc ctaaccgtca gcatgtggta tatggtccct ggaacctacc acagtccagc      540

tactcccacc tcactcgcca gggtgagacc ctcaatttcc tggagattgg atattcccgc      600

tgctgccact gccgcagcca cacaaaccgc ctagagtgtg ccaaacttgt gtgggaggaa      660

gcaatgagcc gattctgtga ggccgagttc tcggtcaaga cccgacccca ctggtgctgc      720

acgcggcagg gggaggctcg gttctcctgc ttccaggagg aagctcccca gccacactac      780

cagctccggg cctgccccag ccatcagcct gatatttcct cgggtcttga gctgcctttc      840

cctcctgggg tgcccacatt ggacaatatc aagaacatct gccacctgag gcgcttccgc      900

tctgtgccac gcaacctgcc agctactgac cccctacaaa gggagctgct ggcactgatc      960

cagctggaga gggagttcca gcgctgctgc cgccagggga acaatcacac ctgtacatgg     1020

aaggcctggg aggataccct tgacaaatac tgtgaccggg agtatgctgt gaagacccac     1080

caccacttgt gttgccgcca ccctcccagc cctactcggg atgagtgctt tgcccgtcgg     1140

gctccttacc ccaactatga ccgggacatc ttgaccattg acatcagtcg agtcaccccc     1200

aacctcatgg gccacctctg tggaaaccaa agagttctca ccaagcataa acatattcct     1260

gggctgatcc acaacatgac tgcccgctgc tgtgacctgc catttccaga acaggcctgc     1320

tgtgcagagg aggagaaatt aaccttcatc aatgatctgt gtggtccccg acgtaacatc     1380

tggcgagacc ctgccctctg ctgttacctg agtcctgggg atgaacaggt caactgcttc     1440

aacatcaatt atctgaggaa cgtggctcta gtgtctggag acactgagaa cgccaagggc     1500

cagggggagc agggctcaac tggaggaaca aatatcagct ccacctctga gcccaaggaa     1560

gaa                                                                   1563


<210>  5534
<211>  861
<212>  DNA
<213>  Homo Sapiens

<400>  5534
gcagaagctc cctgcggtgt ggccccccaa gcacgcatca caggtggcag cagtgcagtc       60

gccggtcagt ggccctggca ggtcagcatc acctatgaag gcgtccatgt gtgtggtggc      120

tctctcgtgt ctgagcagtg ggtgctgtca gctgctcact gcttccccag cgagcaccac      180

aaggaagcct atgaggtcaa gctgggggcc caccagctag actcctactc cgaggacgcc      240

aaggtcagca ccctgaagga catcatcccc caccccagct acctccagga gggctcccag      300

ggcgacattg cactcctcca actcagcaga cccatcacct tctcccgcta catccggccc      360

atctgcctcc ctgcagccaa cgcctccttc cccaacggcc tccactgcac tgtcactggc      420

tggggtcatg tggccccctc agtgagcctc ctgacgccca agccactgca gcaactcgag      480

gtgcctctga tcagtcgtga gacgtgtaac tgcctgtaca acatcgacgc caagcctgag      540

gagccgcact ttgtccaaga ggacatggtg tgtgctggct atgtggaggg gggcaaggac      600

gcctgccagg gtgactctgg gggcccactc tcctgccctg tggagggtct ctggtacctg      660

acgggcattg tgagctgggg agatgcctgt ggggcccgca acaggcctgg tgtgtacact      720

ctggcctcca gctatgcctc ctggatccaa agcaaggtga cagaactcca gcctcgtgtg      780

gtgccccaaa cccaggagtc ccagcccgac agcaacctct gtggcagcca cctggccttc      840

agctctgccc cagcccaggg c                                                861


<210>  5535
<211>  396
<212>  DNA
<213>  Homo Sapiens

<400>  5535
cccccaaaca ggcgaacctg tgtgttcttt gaggcccctg gagtgcgggg aagcacaaag       60

acactgggag agctgctaga tacaggcaca gagctcccca gagctatccg ctgcctctac      120

agccgctgct gctttgggat ctggaacctg acccaagacc gggcacaggt ggaaatgcaa      180

ggatgccgag acagtgatga gccaggctgt gagtccctcc actgtgaccc aagtccccga      240

gcccacccca gccctggctc cactctcttc acctgctcct gtggcactga cttctgcaat      300

gccaattaca gccatctgcc tcctccaggg agccctggga ctcctggctc ccagggtccc      360

caggctgccc caggtgagtc catctggatg gcactg                                396


<210>  5536
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  5536
ggtcctatgc ccaagctggc tgaccggaag ctgtgtgcgg accaggagtg cagccaccct       60

atctccatgg ctgtggccct tcaggactac atggcccccg actgccgatt cctgaccatt      120

caccggggcc aagtggtgta tgtcttctcc aagctgaagg gccgtgggcg gctcttctgg      180

ggaggcagcg ttcagggaga ttactatgga gatctggctg ctcgcctggg ctatttcccc      240

agtagcattg tccgagagga ccagaccctg aaacctggca aagtcgatgt gaagacagac      300

aaatgggatt tctactgcca g                                                321


<210>  5537
<211>  999
<212>  DNA
<213>  Homo Sapiens

<400>  5537
gtcagtccga gtgcctcagc ctggccagag gagaagaatt accaccagcc agccattttg       60

aattcatcgg ctcttcggca aattgcagaa ggcaccagta tctctgaaat gtggcaaaat      120

gacttacagc cattgctgat agagcgatac ccgggatccc ctggaagcta tgctgctcgt      180

cagcacatca tgcagcgaat tcagaggctt caggctgact gggtcttgga aatagacacc      240

ttcttgagtc agacacccta tgggtaccgg tctttctcaa atatcatcag caccctcaat      300

cccactgcta aacgacattt ggtcctcgcc tgccactatg actccaagta tttttcccac      360

tggaacaaca gagtgtttgt aggagccact gattcagccg tgccatgtgc aatgatgttg      420

gaacttgctc gtgccttaga caagaaactc ctttccttaa agactgtttc agactccaag      480

ccagatttgt cactccagct gatcttcttt gatggtgaag aggcttttct tcactggtct      540

cctcaagatt ctctctatgg gtctcgacac ttagctgcaa agatggcatc gaccccgcac      600

ccacctggag cgagaggcac cagccaactg catggcatgg atttattggt cttattggat      660

ttgattggag ctccaaaccc aacgtttccc aatttttttc caaactcagc caggtggttc      720

gaaagacttc aagcaattga acatgaactt catgaattgg gtttgctcaa ggatcactct      780

ttggaggggc ggtatttcca gaattacagt tatggaggtg tgattcagga tgaccatatt      840

ccatttttaa gaagaggtgt tccagttctg catctgatac cgtctccttt ccctgaagtc      900

tggcacacca tggatgacaa tgaagaaaat ttggatgaat caaccattga caatctaaac      960

aaaatcctac aagtctttgt gttggaatat cttcatttg                             999


<210>  5538
<211>  1131
<212>  DNA
<213>  Homo Sapiens

<400>  5538
cagaggttgc cccggatgca ggaggattcc cccttgggag gaggctcttc tggggaagat       60

gacccactgg gcgaggagga tctgcccagt gaagaggatt cacccagaga ggaggatcca      120

cccggagagg aggatctacc tggagaggag gatctacctg gagaggagga tctacctgaa      180

gttaagccta aatcagaaga agagggctcc ctgaagttag aggatctacc tactgttgag      240

gctcctggag atcctcaaga accccagaat aatgcccaca gggacaaaga aggggatgac      300

cagagtcatt ggcgctatgg aggcgacccg ccctggcccc gggtgtcccc agcctgcgcg      360

ggccgcttcc agtccccggt ggatatccgc ccccagctcg ccgccttctg cccggccctg      420

cgccccctgg aactcctggg cttccagctc ccgccgctcc cagaactgcg cctgcgcaac      480

aatggccaca gtgtgcaact gaccctgcct cctgggctag agatggctct gggtcccggg      540

cgggagtacc gggctctgca gctgcatctg cactgggggg ctgcaggtcg tccgggctcg      600

gagcacactg tggaaggcca ccgtttccct gccgagatcc acgtggttca cctcagcacc      660

gcctttgcca gagttgacga ggccttgggg cgcccgggag gcctggccgt gttggccgcc      720

tttctggagg agggcccgga agaaaacagt gcctatgagc agttgctgtc tcgcttggaa      780

gaaatcgctg aggaaggctc agagactcag gtcccaggac tggacatatc tgcactcctg      840

ccctctgact tcagccgcta cttccaatat gaggggtctc tgactacacc gccctgtgcc      900

cagggtgtca tctggactgt gtttaaccag acagtgatgc tgagtgctaa gcagctccac      960

accctctctg acaccctgtg gggacctggt gactctcggc tacagctgaa cttccgagcg     1020

acgcagcctt tgaatgggcg agtgattgag gcctccttcc ctgctggagt ggacagcagt     1080

cctcgggctg ctgagccagt ccagctgaat tcctgcctgg ctgctggtga c              1131


<210>  5539
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5539
aaagctcagg ttaatccagc tatatgccgc tatcctctgg gcatgtcagg aggccagatt       60

ccagatgagg acatcacagc ttccagtcag tggtcagagt ccacagctgc caaatatgga      120

aggctggact cagaagaagg ggatggagcc tggtgccctg agattccagt ggaacctgat      180

gacctgaagg agtttctgca gattgacttg cacaccctcc attttatcac tctggtgggg      240

acccaggggc gccatgcagg aggtcatggc atcgagtttg cccccatgta caagatcaat      300

tacagtcggg atggcactcg ctggatctct tggcggaacc gtcatgggaa acaggtgctg      360

gatggaaata gtaaccccta tgacattttc ctaaaggact tggagccgcc cattgtagcc      420

agatttgttc ggttcattcc agtcaccgac cactccatga atgtgtgtat gagagtggag      480

ctttacggct gtgtctggct agatggcttg gtgtcttaca atgctccagc tgggcagcag      540

tttgtactcc ctggaggttc catcatttat ctgaatgatt ctgtctatga tggagctgtt      600

ggatacagca tgacagaagg gctaggccaa ttgaccgatg gtgtgtctgg cctggacgat      660

ttcacccaga cccatgaata ccacgtgtgg cccggctatg actatgtggg ctggcggaac      720

gagagtgcca ccaatggcta cattgagatc atgtttgaat ttgaccgcat caggaatttc      780

actaccatga aggtccactg caacaacatg tttgctaaag gtgtgaagat ctttaaggag      840

gtacagtgct acttccgctc tgaagccagt gagtgggaac ctaatgccat ttccttcccc      900

cttgtcctgg atgacgtcaa ccccagtgct cggtttgtca cggtgcctct ccaccaccga      960

atggccagtg ccatcaagtg tcaataccat tttgcagata cctggatgat gttcagtgag     1020

atcaccttcc aatcagatgc tgcaatgtac aacaactctg aagccctgcc cacctctcct     1080

atggcaccca caacctatga tccaatgctt aaagttgatg acagcaacac tcgg           1134


<210>  5540
<211>  2211
<212>  DNA
<213>  Homo Sapiens

<400>  5540
ggcaggggtg gagatggggg tgaacccagc cagcttcccc attgcccctc tgtatctccc       60

agtgcccagc cttggacaca ccctggccag agccagctgt ttgcagacct gagccgagag      120

gagctgacgg ctgtgatgcg ctttctgacc cagcggctgg ggccagggct ggtggatgca      180

gcccaggccc ggccctcgga caactgtgtc ttctcagtgg agttgcagct gcctcccaag      240

gctgcagccc tggctcactt ggacaggggg agccccccac ctgcccggga ggcactggcc      300

atcgtcttct ttggcaggca accccagccc aacgtgagtg agctggtggt ggggccactg      360

cctcacccct cctacatgcg ggacgtgact gtggagcgtc atggaggccc cctgccctat      420

caccgacgcc ccgtgctgtt ccaagagtac ctggacatag accagatgat cttcaacaga      480

gagctgcccc aggcttctgg gcttctccac cactgttgct tctacaagca ccggggacgg      540

aacctggtga caatgaccac ggctccccgt ggtctgcaat caggggaccg ggccacctgg      600

tttggcctct actacaacat ctcgggcgct gggttcttcc tgcaccacgt gggcttggag      660

ctgctagtga accacaaggc ccttgaccct gcccgctgga ctatccagaa ggtgttctat      720

caaggccgct actacgacag cctggcccag ctggaggccc agtttgaggc cggcctggtg      780

aatgtggtgc tgatcccaga caatggcaca ggtgggtcct ggtccctgaa gtcccctgtg      840

cccccgggtc cagctccccc tctacagttc tatccccaag gcccccgctt cagtgtccag      900

ggaagtcgag tggcctcctc actgtggact ttctcctttg gcctcggagc attcagtggc      960

ccaaggatct ttgacgttcg cttccaagga gaaagactag tttatgagat aagcctccaa     1020

gaggccttgg ccatctatgg tggaaattcc ccagcagcaa tgacgacccg ctatgtggat     1080

ggaggctttg gcatgggcaa gtacaccacg cccctgaccc gtggggtgga ctgcccctac     1140

ttggccacct acgtggactg gcacttcctt ttggagtccc aggcccccaa gacaatacgt     1200

gatgcctttt gtgtgtttga acagaaccag ggcctccccc tgcggcgaca ccactcagat     1260

ctctactcgc actactttgg gggtcttgcg gaaacggtgc tggtcgtcag atctatgtcc     1320

accttgctca actatgacta tgtgtgggat acggtcttcc accccagtgg ggccatagaa     1380

atacgattct atgccacggg ctacatcagc tcggcattcc tctttggtgc tactgggaag     1440

tacgggaacc aagtgtcaga gcacaccctg ggcacggtcc acacccacag cgcccacttc     1500

aaggtggatc tggatgtagc aggactggag aactgggtct gggccgagga tatggtcttt     1560

gtccccatgg ctgtgccctg gagccctgag caccagctgc agaggctgca ggtgacccgg     1620

aagctgctgg agatggagga gcaggccgcc ttcctcgtgg gaagcgccac ccctcgctac     1680

ctgtacctgg ccagcaacca cagcaacaag tggggtcacc cccggggcta ccgcatccag     1740

atgctcagct ttgctggaga gccgctgccc caaaacagct ccatggcgag aggcttcagc     1800

tgggagaggt accagctggc tgtgacccag cggaaggagg aggagcccag tagcagcagc     1860

gttttcaatc agaatgaccc ttgggccccc actgtggatt tcagtgactt catcaacaat     1920

gagaccattg ctggaaagga tttggtggcc tgggtgacag ctggttttct gcatatccca     1980

catgcagagg acattcctaa cacagtgact gtggggaacg gcgtgggctt cttcctccga     2040

ccctataact tctttgacga agacccctcc ttctactctg ccgactccat ctacttccga     2100

ggggaccagg atgctggggc ctgcgaggtc aaccccctag cttgcctgcc ccaggctgct     2160

gcctgtgccc ccgacctccc tgccttctcc cacgggggct tctctcacaa c              2211


<210>  5541
<211>  2331
<212>  DNA
<213>  Homo Sapiens

<400>  5541
accaaagata tctccattaa catataccat tctgaaacta aagacataga caatccccca       60

agaaatgaaa caactgaaag tactgaaaaa atgtacaaaa tgtcaactat gagacgaata      120

ttcgatttgg caaagcatcg aacaaaaaga tccgcatttt tcccaacggg ggttaaagtc      180

tgtccacagg aatccatgaa acagatttta gacagtcttc aagcttatta tagattgaga      240

gtgtgtcagg aagcagtatg ggaagcatat cggatctttc tggatcgcat ccctgacaca      300

ggggaatatc aggactgggt cagcatctgc cagcaggaga ccttctgcct ctttgacatt      360

ggaaaaaact tcagcaattc ccaggagcac ctggatcttc tccagcagag aataaaacag      420

agaagtttcc ctgacagaaa agatgaaata tctgcagaga agacattggg agagcctggt      480

gaaaccattg tcatttcaac agatgttgcc aacgtctcac ttgggccttt ccctctcact      540

cctgatgaca ccctcctcaa tgaaattctc gataatacac tcaacgacac caagatgcct      600

acaacagaaa gagaaacaga attcgctgtg ttggaggagc agagggtgga gctcagcgtc      660

tctctggtaa accagaagtt caaggcagag ctcgctgact cccagtcccc atattaccag      720

gagctagcag gaaagtccca acttcagatg caaaagatat ttaagaaact tccaggattc      780

aaaaaaatcc atgtgttagg atttagacca aagaaagaaa aagatggctc aagctccaca      840

gagatgcaac ttacggccat ctttaagaga cacagtgcag aagcaaaaag ccctgcaagt      900

gacctcctgt cttttgattc caacaaaatt gaaagtgagg aagtctatca tggaaccatg      960

gaggaggaca agcaaccaga aatctatctc acagctacag acctcaaaag gctgatcagc     1020

aaagcactag aggaagaaca atctttggat gtggggacaa ttcagttcac tgatgaaatt     1080

gctggatcac tgccagcctt tggtcctgac acccaatcag agctgcccac atcttttgct     1140

gttataacag aggatgctac tttgagtcca gaacttcctc ctgttgaacc ccagcttgag     1200

acagtggacg gagcagagca tggtctacct gacacttctt ggtctccacc tgctatggcc     1260

tctacctccc tgtcagaagc tccacctttc tttatggcat caagcatctt ctctctgact     1320

gatcaaggca ccacagatac aatggccact gaccagacaa tgctagtacc agggctcacc     1380

atccccacca gtgattattc tgcaatcagc caactggctc tgggaatttc acatccacct     1440

gcatcttcag atgacagccg atcaagtgca ggtggcgaag atatggtcag agacctagat     1500

gaaatggatc tgtctgacac tcctgcccca tctgaggtac cagagctcag cgaatatgtt     1560

tctgtcccag atcatttctt ggaggatacc actcctgtct cagctttaca gtatatcacc     1620

actagttcta tgaccattgc ccccaagggc cgagagctgg tagtgttctt cagtctgcgt     1680

gttgctaaca tggccttctc caacgacctg ttcaacaaga gctctctgga gtaccgagct     1740

ctggagcaac aattcacaca gctgctggtt ccatatctac gatccaatct tacaggattt     1800

aagcaacttg aaatacttaa cttcagaaac gggagtgtga ttgtgaatag caaaatgaag     1860

tttgctaagt cagtgccgta taacctcacc aaggctgtgc acggggtctt ggaggatttt     1920

cgttctgctg cagcccaaca actccatctg gaaatagaca gctactctct caacattgaa     1980

ccagctgatc aagcagatcc ctgcaagttc ctggcctgcg gcgaatttgc ccaatgtgta     2040

aagaacgaat ggactgagga agcggagtgt cgctgcaaac caggatatga cagccagggg     2100

agcctggacg gtctggaacc aggcctctgt ggccctggca caaaggaatg cgaggtcctc     2160

cagggaaagg gagctccatg caggttgcca gatcactctg aaaatcaagc atacaaaact     2220

agtgttaaaa agttccaaaa tcaacaaaat aacaaggtaa tcagtaaaag aaattctgaa     2280

ttactgaccg tagaatatga agaatttaac catcaagatt gggaaggaaa t              2331


<210>  5542
<211>  1350
<212>  DNA
<213>  Homo Sapiens

<400>  5542
aaagaagttt gctatgaaag gttagggtgt ttcaaagatg gtttaccatg gaccaggact       60

ttctcaacag agttggtagg tttaccctgg tctccagaga agataaacac tcgtttcctg      120

ctctacacta tacacaatcc caatgcctat caggagatca gtgcggttaa ttcttcaact      180

atccaagcct catattttgg aacagacaag atcacccgta tcaacatagc tggatggaaa      240

acagatggca aatggcagag agacatgtgc aatgtgttgc tacagctgga agatataaat      300

tgcattaatt tagattggat caacggttca cgggaataca tccatgctgt aaacaatctc      360

cgtgttgttg gtgctgaggt ggcttatttt attgatgttc tcatgaaaaa atttgaatat      420

tccccttcta aagtgcactt gattggccac agcttgggag cacacctggc tggggaagct      480

gggtcaagga taccaggcct tggaagaata actgggttgg acccagctgg gccatttttc      540

cacaacactc caaaggaagt caggctagac ccctcggatg ccaactttgt tgacgttatt      600

catacaaatg cagctcgcat cctctttgag cttggtgttg gaaccattga tgcttgtggt      660

catcttgact tttacccaaa tggagggaag cacatgccag gatgtgaaga cttaattaca      720

cctttactga aatttaactt caatgcttac aaaaaagaaa tggcttcctt ctttgactgt      780

aaccatgccc gaagttatca attttatgct gaaagcattc ttaatcctga tgcatttatt      840

gcttatcctt gtagatccta cacatctttt aaagcaggaa attgcttctt ttgttccaaa      900

gaaggttgcc caacaatggg tcattttgct gatagatttc acttcaaaaa tatgaagact      960

aatggatcac attatttttt aaacacaggg tccctttccc catttgcccg ttggaggcac     1020

aaattgtctg ttaaactcag tggaagcgaa gtcactcaag gaactgtctt tcttcgtgta     1080

ggcggggcaa ttgggaaaac tggggagttt gccattgtca gtggaaaact tgagccaggc     1140

atgacttaca caaaattaat cgatgcagat gttaacgttg gaaacattac aagtgttcag     1200

ttcatctgga aaaaacattt gtttgaagat tctcagaata agttgggagc agaaatggtg     1260

ataaatacat ctgggaaata tggatataaa tctaccttct gtagccaaga cattatggga     1320

cctaatattc tccagaacct gaaaccatgc                                      1350


<210>  5543
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  5543
cagcccacaa tgacccagac ctctagctct cagggaggcc ttggcggtct aagtctgacc       60

acagagccag tttcttccaa cccaggatac atcccttcct cagaggctaa caggccaagc      120

catctgtcca gcactggtac cccaggcgca ggtgtcccca gcagtggaag agacggaggc      180

acaagcagag acacatttca aactgttccc cccaattcaa ccaccatgag cctgagcatg      240

agggaagatg cgaccatcct gcccagcccc acgtcagaga ctgtgctcac tgtggctgca      300


<210>  5544
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  5544
agttctgagt ggtctgtggg ccaggtcagc accaacacat catacaaggc cttcagttct       60

gagtggatca gcgctgatat tgggctgcag gtcgggctgg gtggagtcaa catcacactc      120

acagggaccc ccgtgcagca gctgaatgag accatcaatt acaacgagga gttcacctgg      180

cgcctgggtg agaactatgc tgaggagtat gcaaaggctc tggagaaggg gctgccagac      240

cctgtgttgt acctagctga gaagttcact ccaagaagcc catgtggcct ataccgccag      300

taccgcctgg cgggacacta cacctcagcc atg                                   333


<210>  5545
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  5545
gtgggtacag tgaacaccaa cacatcctac aaagccttca gcgcagcgcg cgttacagcc       60

cgtgtccgtc tgctcgtggg cctggagggc attaatatta cactcacagg gaccccagtg      120

catcagctga acgagaccat tgactacaac gagcagttca cctggcgtct gaaagagaat      180

tacgccgcgg agtacgcgaa cgcactggag aaggggctgc cggacccagt gctctacctg      240

gcggagaagt tcacaccgag tagcccttgc ggcctgtacc accagtacca cctggcggga      300

cactacgcct cggccacg                                                    318


<210>  5546
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  5546
ggaattttca ataaacgtga cttcactagg tggcctaagc cccgatgtaa aatgtatatc       60

ccactggacc ctgattacaa tgcagactgc cccaatgtga cagcacctgt ttgtgcctca      120

aatggccaca ctttccagaa tgagtgtttc ttttgtgttg aacagaggga atttcattat      180

cgtataaaat ttgaaaaata tggaaaatgt gat                                   213


<210>  5547
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  5547
cacggctgtc tgcactgcca cagcaacttc tccaagaagt tctccttcta ccgccaccat       60

gtgaacttca agtcctggtg ggtgggcgac atccccgtgt caggggcgct gctcaccgac      120

tggagcgacg acacgatgaa ggagctgcac ctggccatcc ccgccaagat cacccgggag      180

aagctggacc aagtggcgac agcagtgtac cagatgatgg atcagctgta ccaggggaag      240

atgtacttcc ccgggtattt ccccaacgag ctgcgaaaca tcttccggga gcaggtgcac      300

ctcatccaga acgccatcat cgaaagccgc atcgactgtc agcaccgctg tggcatcttc      360

cagtacgaga ccatctcctg caacaactgc acagactcgc acgtcgcctg ctttggctat      420

aactgcgagt cctcggcgca gtggaagtca gctgtccagg gcctcctgaa ctacataaat      480

aactggcaca aacaggacac gagcatgagc ctggtatcgc cagccttaag gtgtctggag      540

cccccacact tggccaacct gaccttggaa gatgctgctg agtgtctcaa gcagcac         597


<210>  5548
<211>  2451
<212>  DNA
<213>  Homo Sapiens

<400>  5548
tgtggccagg ctcccctgga ccctgtctac ctgccggcag ccctggagct cctagacgcc       60

cctgaacact tccgtgtgca gcaggtgggc cactacccac ctgccaactc ctctctgagc      120

tcccgatctg agacctttct gctcctacag ccctggccca gggcccagcc acttctccgg      180

gcctcctacc caccttttgc cactcagcag gtggtccccc ctcgagtcac tgagccccac      240

caacggccag tcccatggga cgtgcgggcc gtttcagtgg aagcggctgt gactccagca      300

gagccctacg cccgggttct cttccacctc aaagggcagg attggccacc agggtctggc      360

agcctgccct gtgcccggct ccatgccaca caccctgccg gcactgctca ccaagcctgc      420

cgcttccagc catccctggg cgcctgcgtg gtggagctgg agcttccctc gcactggttc      480

tcacaggcct ccaccacacg ggccgagctg gcctacacgc ttgagcctgc agctgagggc      540

cctgggggct gtggctccgg cgaggagaac gaccctgggg agcaggccct cccagtgggg      600

ggtgtggagc tgcgcccagc agaccccccg cagtaccagg aggtacctct ggacgaggct      660

gtgactctgc gggtgcctga catgccagtg cggcccggcc agctctttag tgctaccctc      720

ctgcttcggc acaacttcac agccagcctc ctgaccctgc ggatcaaggt gaagaagggg      780

ctgcatgtga cagccgcccg cccagcccag cccacactct ggactgccaa gctggaccgc      840

ttcaagggct ccaggcacca caccaccctc atcacctgcc accgtgctgg gctcacagag      900

ccagattcca gtccccttga actgtctgag ttcctatggg tggactttgt ggtggagaat      960

agcactggtg ggggcgtagc ggtcactcgc cccgtcacgt ggcagctgga gtacccaggc     1020

caggcccctg aagcagagaa ggacaaaatg gtgtgggaaa tcctggtgtc tgagcgggac     1080

atcagagccc ttatcccact ggccaaggct gaggagctgg tgaatacagc accactgact     1140

ggagtgcccc agcatgtccc cgtgcgcctt gtcactgtgg acggcggggg ggccttggtg     1200

gaggtgacag agcatgtcgg ctgcgagtct gccaacacac aggtcctgca ggtgtctgag     1260

gcctgtgatg ccgtgttcgt ggctggcaag gagagccggg gcgcccgggg ggtgcgagtg     1320

gacttctggt ggcgccggct ccgcgcctcg ctgcggctga ccgtgtgggc ccccctgcta     1380

ccgctgcgta tcgagctcac cgacaccacc ctcgagcagg tccgcggctg gagggtacct     1440

ggccctgctg aagggcctgc ggaacccgct gcagaggcgt cggatgaggc cgagcggcgc     1500

gcccgtggct gccacctgca gtaccagcgg gccggtgtgc gcttcctcgc ccccttcgcg     1560

gcccacccgc tggacggcgg ccgccgcctc acgcacctgc ttggccccga ctggctgcta     1620

gacgtgtccc acctcgtggc gccacacgcc cgcgtgctgg actcgcgtgt agcctctctg     1680

gagggtggcc gtgtcgtggt gggccgggag cccggtgtca cctccattga ggtgcgttcc     1740

ccactgtctg actccatcct gggggagcag gcgctggctg tgacggacga caaggtctca     1800

gtgctggagc tgagggtgca gccagtgatg ggcatctcgc tgaccttgag ccggggcact     1860

gcccaccccg gggaggtcac agctacgtgc tgggcacagt cagcccttcc cgccccaaag     1920

caggaggtgg ccctctccct atggctgtcc ttctctgatc acactgtggc cccagctgag     1980

ctctacgacc gccgtgacct gggactgtcc gtctcagccg aggagcctgg tgccatcctg     2040

ccagctgagg agcagggtgc ccagctcggg gtggtggtga gtggggcagg cgccgagggg     2100

ctgccgctgc atgtggctct gcacccgccc gagccctgcc gccggggccg ccaccgtgtg     2160

cctctggcct ctggcaccgc ctggctgggg ctgccccctg cctccactcc agcccctgct     2220

ctcccatcca gccctgcttg gagcccacca gccacagaag ccaccatggg tggtaaacgg     2280

caggtggcag gcagtgtcgg gggcaacaca ggtgtgaggg gcaagtttga gcgggcagag     2340

gaggaggcca ggaaggagga gaccgaagcc agggaggagg aggaggaaga ggaggaggag     2400

atggtccctg cccctcagca tgtcactgag ctagagctgg gcatgtacgc c              2451


<210>  5549
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  5549
ctgaaccgaa ggaagaagca agtgggcact ggcctggggg gcaactgcac aggctgtatc       60

atctgctcag aggagaacgg ctgttccacc tgccagcaga ggctcttcct gttcatccgc      120

cgggaaggca tccgccagta cggcaagtgc ctgcacgact gtccccctgg gtacttcggc      180

atccgcggcc aggaggtcaa caggtgcaaa aaatgtgggg ccacttgtga gagctgcttc      240

agccaggact tctgcatccg gtgcaagagg cagttttact tgtacaaggg gaagtgtctg      300

cccacctgcc cgccgggcac tttggcccac cagaacacac gggagtgcca gggggagtgt      360

gaactgggtc cctggggcgg ctggagcccc tgcacacaca atggaaagac ctgcggctcg      420

gcttggggcc tggagagccg ggtacgagag gctggccggg ctgggcatga ggaggcagcc      480

acctgccagg tgctttctga gtcaaggaaa tgtcccatcc agaggccctg cccaggagag      540

aggagccccg gccagaagaa gggcaggaag gaccggcgcc cacgcaagga caggaagctg      600

gaccgcaggc tggacgtgag gccgcgccag cccggcctgc agccc                      645


<210>  5550
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  5550
ttccaacctc ctcaattagg cagaacaaac atgcattact ccaaattgcc ccgcactgcg       60

atagagacag agttcaagca gaatgttggc ccaccaccca aggatctgac cactgaagtt      120

tacttccctt caatcaaatc gagatcacat cttcctgcag ttttctataa tcagtatttc      180

aagcatccaa aatgtgtagg agaatatgga cccaagaacg gagcagagag acaaatagag      240

gaatggaaag ttttgcctac aaccatgatg ttctcaatgt tagctgactg tgttctaaaa      300

tccactccaa ttcccatttt gggagttgct atg                                   333


<210>  5551
<211>  1893
<212>  DNA
<213>  Homo Sapiens

<400>  5551
gagatggacg aagttggagt tcaaaaatgc aagaatgcct tgaaactacc tgtcctggaa       60

gtcctacctg gagggggctg ggacaatctg cggaatgtgg acatgggacg agttatggaa      120

ttgacttact ccaactgcag gacaacagag gatggacagt atatcatccc tgatgaaatc      180

ttcaccattc cccagaaaca gagcaacctg gagatgaact cagaaatcct ggaatcctgg      240

gcaaattacc agagtagcac ctcctactcc atcaacacag aactctctct tttttccaaa      300

gtcaatggca agttttccac tgagttccag aggatgaaga ccctccaagt gaaggaccaa      360

gctataacta cccgagttca ggtaagaaac ctcgtctaca cagtcaaaat caacccaact      420

ttagagctaa gctcaggttt taggaaggaa ctccttgaca tctctgaccg tctagagaac      480

aaccagacga ggatggccac ctacctggca gaactcctgg tgctcaacta tggcacccac      540

gtcaccacca gtgtcgacgc tggggctgct cttattcagg aggaccacct cagggcctcc      600

ttcctccaag acagccagag cagtcgtagt gccgtgaccg cctctgctgg acttgccttt      660

caaaacaccg tgaacttcaa atttgaggaa aactatacct cgcagaatgt cctcaccaag      720

agctacctct caaaccgaac caactccagg gtgcagagca ttggaggggt tcctttttac      780

ccaggcatca ccctccaggc ctggcagcag ggtatcacca accacctggt ggccatcgac      840

cgctctggcc tgccgctgca tttcttcatc aaccccaaca tgctacctga cttgccaggc      900

cccctggtga agaaggtgtc aaagacagtg gaaactgctg tgaagcgcta ttatacattc      960

aacacctacc ctggctgcac agatctcaat tctcccaact tcaattttca ggccaacacg     1020

gatgatggct cctgcgaggg gaaaatgacc aacttctctt tcggtggggt ttatcaggaa     1080

tgcactcagc tctcagggaa tagggatgtc ctcctctgcc aaaagttgga gcagaagaat     1140

ccactcactg gtgatttctc ctgcccctct ggctactccc cggtgcacct gttatcccag     1200

atccacgagg agggttacaa ccacctggag tgtcatcgaa agtgcactct cctcgtcttc     1260

tgcaagaccg tgtgtgaaga tgtgttccag gtggcaaaag ctgaatttag ggctttttgg     1320

tgtgtggcca gcagccaagt acctgaaaac tcaggactgc tttttggggg cctcttcagc     1380

agcaagagca taaaccccat gacaaatgca cagtcatgcc cagccggcta ctttccactg     1440

agactctttg aaaacctcaa ggtatgtgtt tctcaggact atgagttggg aagcaggttt     1500

gcggtcccct ttggcgggtt ctttagctgc acagttggga accccctggt agatcctgct     1560

atatccagag atttaggggc actgtctctg aaaaagtgcc ccgggggctt cagccagcac     1620

ccagccctca tcagcgatgg atgccaagtg tcctattgcg tcaaatccgg gctcttcaca     1680

ggagggtccc tgccccctgc caggctccca cctttcaccc ggccacccct catgagtcag     1740

gctgccacca atactgtcat agtgaccaat tctgagaatg cgagatcctg gattaaagac     1800

tcccagaccc accagtggag gctgggagaa ccgatagagc tgcggagggc catgaatgtc     1860

atccatgggg atggtggtgg tctgtcagga ggg                                  1893


<210>  5552
<211>  1272
<212>  DNA
<213>  Homo Sapiens

<400>  5552
aagtctatct cttgtctaaa acctgctcga cttccaattt atcaaaggaa accttttata       60

gctgcttgga atgctccaac agatcagtgt ttgataaaat ataatttaag actaaatttg      120

aaaatgtttc ctgtgattgg aagcccactg gccaaggcca gggggcaaaa tgtcactata      180

ttttatgtca acagattggg atactatccg tggtatacat cacaaggggt ccccattaat      240

ggaggtctcc cacagaacat aagtttacaa gtacatctgg aaaaagctga ccaagatatt      300

aattattaca tccctgctga agatttcagt ggacttgctg ttatagattg ggaatattgg      360

cgaccacagt gggcccggaa ctggaactca aaagatgttt acagacagaa gtcaagaaag      420

cttatttccg atatgggaaa gaatgtatca gctaccgata ttgaatattt agccaaagtg      480

acctttgaag aaagtgcaaa agctttcatg aaggaaacca tcaaattggg aattaagagc      540

cgacccaaag gcctttgggg ttattattta tatcctgatt gccacaatta taacgtttat      600

gccccaaact actctgggtc atgcccagaa gacgaagtct tgaggaacaa tgagctctct      660

tggctctgga acagcagtgc tgctttatat ccttctatcg gtgtctggaa atcccttgga      720

gacagtgaaa acattttgcg cttctccaaa tttcgggtgc atgaatccat gaggatctct      780

accatgacat ctcatgatta tgctctgcct gtatttgtct acacaaggct agggtacaga      840

gatgaacctt tatttttcct ttctaagcaa gatctagtca gcaccatagg agaaagtgct      900

gccttgggag ctgcaggcat tgttatttgg ggagacatga atttaacttc atccaaggcc      960

aactgtacaa aggtgaagca gtttgtgagt tctgatttag ggagctacat agccaatgtg     1020

accagagctg ctgaggtatg cagccttcac ctctgcagga acaatggcag gtgcataagg     1080

aagatgtgga acgcgcccag ttaccttcac ttgaaccctg caagttacca catagaggcc     1140

tctgaggacg gggagtttac tgtgaaagga aaagcatctg atacagacct ggcagtgatg     1200

gcagatacat tttcctgtca ttgttatcag ggatatgaag gagctgattg cagagaaata     1260

aagacggctg at                                                         1272


<210>  5553
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  5553
agccggggga tcaaggggaa aaggcagagg cggatcagtg ccgaggggag ccaggcctgt       60

gccaaaggct gtgagctctg ctctgaagtc aacggctgcc tcaagtgctc acccaagctg      120

ttcatcctgc tggagaggaa cgacatccgc caggtgggcg tctgcttgcc gtcctgccca      180

cctggatact tcgacgcccg caaccccgac atgaacaagt gcatcaaatg caagatcgag      240

cactgtgagg cctgcttcag ccataacttc tgcaccaagt gtaaggaggg cttgtacctg      300

cacaagggcc gctgctatcc agcttgtccc gagggctcct cagctgccaa tggcaccatg      360

gagtgcagta gtcctgcgca atgtgaaatg agcgagtggt ctccgtgggg gccctgctcc      420

aagaagcagc agctctgtgg tttccggagg ggctccgagg agcggacacg cagggtgcta      480

catgcccctg tgggggacca tgctgcctgc tctgacacca aggagacccg gaggtgcaca      540

gtgaggagag tgccgtgtcc tgaggggcag aagaggagga agggaggcca gggccggcgg      600

gagaatgcca acaggaacct ggccaggaag gagagcaagg aggcgggtgc tggctctcga      660

agacgcaagg ggcagcaaca gcagcagcag caagggacag tggggccact cacatctgca      720

gggcctgcc                                                              729


<210>  5554
<211>  1695
<212>  DNA
<213>  Homo Sapiens

<400>  5554
cagaccgatg ccaccccggc ggtgacgaca gagggcctca actccaccga ggcagccctg       60

gccaccttcg gaactttccc gtcgaccagg ccccccggga ctcccagggc tccagggccc      120

tcctccggcc ccaggcctac cccagtcacg gacgttgctg ttctctgtgt ctgtgactta      180

tccccagcac agtgtgacat caactgctgc tgtgatcccg actgcagctc cgtggatttc      240

agtgtctttt ctgcctgctc agttccagtt gtcacgggcg acagccagtt ttgtagtcaa      300

aaagcagtca tctattcatt gaattttaca gcaaacccac ctcaaagagt atttgaactt      360

gttgaccaga ttaatccatc tattttctgc attcatatta caaactataa acctgcatta      420

tcctttatta atccagaagt acctgatgaa aacaattttg atacattgat gaaaacatct      480

gatggtttta cattgaatgc tgaatcatat gtttccttca caaccaaact ggatattcct      540

actgctgcta aatatgagta tggggttcct ctgcagactt cagattcgtt tctgagattt      600

ccttcgtccc tgacatcatc tctgtgcact gataataacc ctgcagcgtt tctggtgaac      660

caggctgtta agtgcaccag aaaaataaat ttagaacagt gtgaagaaat tgaagccctc      720

agcatggctt tttacagcag cccggaaatt ctgagggtac ctgattcaag aaaaaaggtc      780

cctatcactg ttcagtccat cgtcattcag tctctaaata aaacgctcac ccgacgggag      840

gacactgatg tgctgcagcc gactctcgtc aacgctggac actttagcct ttgcgtgaat      900

gttgttcttg aggtaaagta cagcctcaca tacacagatg caggtgaagt caccaaagct      960

gatctctcat tcgttctggg gacagttagc agcgtagtgg tcccactgca gcaaaagttt     1020

gaaattcatt ttcttcagga aaatacccag ccagtccctc tcagtggaaa ccctggttat     1080

gtcgtggggc tcccattagc tgctggattc cagcctcata aggggtctgg gattattcag     1140

accacaaata gatatggaca gcttactatt cttcatagca caactgagca agactgctta     1200

gcactggagg gggtccggac cccagtatta tttggttaca ctatgcaatc tggctgtaaa     1260

ctaagactga ctggagctct cccgtgtcag ctcgtagcac agaaggtgaa gagcctgctg     1320

tggggccagg gcttcccaga ttacgtggcc ccttttggaa attcccaggc ccaggacatg     1380

ctggactggg tgcccatcca cttcatcacc cagtcattca acaggaagga ttcctgccag     1440

ctcccagggg ctttggttat agaagtgaag tggactaaat acggatccct gctgaatcca     1500

caggccaaaa tagtcaatgt aactgcaaat ctaatttcat cctcctttcc tgaggccaac     1560

tcaggaaatg aaaggacgat tcttatttcc actgcggtta cttttgtgga tgtgtctgca     1620

cctgcagagg caggcttcag agctccacca gccatcaatg ccaggctgcc ctttaacttc     1680

ttcttcccgt ttgtt                                                      1695


<210>  5555
<211>  894
<212>  DNA
<213>  Homo Sapiens

<400>  5555
agtccgagca tcccgctgga gaagctggcc caggcaccag agcagccggg ccaggagaag       60

cgtgagcacg cctctcggga cggcccgggg cgggtgaacg agctcgggcg cccggcgagg      120

gacgagggcg gcagcggccg ggactggaag agcaagagcg gccgtgggct cgccggccgt      180

gagccgtgga gcaagctgaa gcaggcctgg gtctcccagg gcgggggcgc caaggccggg      240

gatctgcagg tccggccccg cggggacacc ccgcaggcgg aagccctggc cgcagccgcc      300

caggacgcga ttggcccgga actcgcgccc acgcccgagc cacccgagga gtacgtgtac      360

ccggactacc gtggcaaggg ctgcgtggac gagagcggct tcgtgtacgc gatcggggag      420

aagttcgcgc cgggcccctc ggcctgcccg tgcctgtgca ccgaggaggg gccgctgtgc      480

gcgcagcccg agtgcccgag gctgcacccg cgctgcatcc acgtcgacac gagccagtgc      540

tgcccgcagt gcaaggagag gaagaactac tgcgagttcc ggggcaagac ctatcagact      600

ttggaggagt tcgtggtgtc tccatgcgag aggtgtcgct gtgaagccaa cggtgaggtg      660

ctatgcacag tgtcagcgtg tccccagacg gagtgtgtgg accctgtgta cgagcctgat      720

cagtgctgtc ccatctgcaa aaatggtcca aactgctttg cagaaaccgc ggtgatccct      780

gctggcagag aagtgaagac tgacgagtgc accatatgcc actgtactta tgaggaaggc      840

acatggagaa tcgagcggca ggccatgtgc acgagacatg aatgcaggca aatg            894


<210>  5556
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  5556
ggggacaccc gaccacgttt cttgcagcag gataagtatg agtgtcattt cttcaacggg       60

acggagcggg tgcggttcct gcacagagac atctataacc aagaggagga cttgcgcttc      120

gacagcgacg tgggggagta ccgggcggtg acggagctgg ggcggcctga cgctgagtac      180

tggaacagcc agaaggactt cctggaagac aggcgcgccg cggtggacac ctactgcaga      240

cacaactacg gggttggtga gagcttcaca gtgcagcggc gagttgagcc taaggtgact      300

gtgtatcctg caaggaccca gaccctgcag caccacaacc tcctggtctg ctctgtgaat      360

ggtttctatc caggcagcat tgaagtcagg tggttccgga acagccagga agagaaggct      420

ggggtggtgt ccacaggcct gattcagaat ggagactgga ccttccagac cctggtgatg      480

ctggaaacag ttcctcgaag tggagaggtt tacacctgcc aagtggagca cccaagcgtg      540

acgagccctc tcacagtgga atggagagca cagtctgaat ctgcacagag caag            594


<210>  5557
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5557
atgtttggga atgatggagt caaagttcgc acctgcacta gccagaaagc cgtatgtttc       60

ttcgggtgtc cgccaggata caggtggatt gcgttctgcc acaatattct gtcttgctgt      120

aaaaatatga cacgttttca acccccgcaa gccaaagatc catgggttca t               171


<210>  5558
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5558
ggacccaatg tctacataca aaaaatcttt gcttcatgtt ggcgactgca aggtacttgc       60

cggccaaaat gtctaaaaaa cgaacaatat cgtattttgt gtgatactat acatttgtgc      120

tgtgtaaacc caaaatattt acctatactg actgggaaa                             159


<210>  5559
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  5559
ggcctgttca gatcccacaa tggcaagagc cgagagcctt ggaatccatg tgagctttac       60

caaggcatgt gcagaaacgc ctgcagagaa tatgaaatcc aatacttaac ctgcccaaat      120

gatcaaaagt gctgcctgaa actttctgtg aaaataacca gttctaaaaa tgtgaaggag      180

gattacgact ctaactccaa cttgtcagtt acaaacagtt caagctactc tcacatt         237


<210>  5560
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  5560
cagactgccc cagatggatg gatcagaagg tgctattatg gaactggcag atgcaggaaa       60

tcatgcaaag aaattgagag gaagaaagaa aaatgtgggg aaaaacatat ttgctgtgtc      120

cctaaagaaa aggataaact atcacacatt cacgaccaaa aagagacaag tgagctatat      180

atc                                                                    183


<210>  5561
<211>  198
<212>  DNA
<213>  Homo Sapiens

<400>  5561
ggtccatcag ttccacagaa aaaaacaaga gaagttgcag agagaaaaag agaatgtcag       60

cttgttcgtg gtgcttgcaa gccggaatgc aacagctggg aatatgtata ttattactgc      120

aatgttaacc cctgctgtgc ggtatgggaa taccaaaagc caatcattaa caaaatcact      180

agtaaactcc atcaaaaa                                                    198


<210>  5562
<211>  339
<212>  DNA
<213>  Homo Sapiens

<400>  5562
atgaaattat tgacaaccat atgtagactg aaacttgaaa aaatgtactc aaagacaaat       60

acatcttcca caatatttga aaaggcccga catgggacag agaaaatcag cacagccaga      120

agtgaagggc accatatcac ctttagtagg tggaagtcat gtacagcgat tggaggtcga      180

tgtaaaaatc aatgtgatga tagtgaattt aggatttcat actgtgcaag acctacaact      240

cattgctgcg tgacagaatg tgaccctacg gacccaaata attggatccc aaaggactca      300

gtagggactc aagaatggta ccctaaagac tcacgtcat                             339


<210>  5563
<211>  1056
<212>  DNA
<213>  Homo Sapiens

<400>  5563
atggaggcaa gctcttctgg aatcactaat ggaaaaacca aagtcttcca cccagaagga       60

ggtgtggatt tgcaaggcta ccagctggat atgcaaatac tacctgacgg gccaaagagt      120

gatgtggact tttcagagat tcttaatgca atacaagaaa tggccaagga tgtcaatatt      180

ctttttgatg aattagaagc tgtcagcagt ccttgcaaag atgacgattc tcttcttcac      240

cctggaaacc tgactagtac ttcagatgat gccagcagat tggaagccgg gggagagaca      300

gtgccagaaa gaaacaaatc aaatggactt tactttcgag atggaaagtg tcgaattgac      360

tacatccttg tgtacagaaa atccaacccc cagactgaaa agagagaagt atttgaaaga      420

aacattagag cagaaggatt gcaaatggag aaagagtcct ctctaataaa tagtgacatt      480

atctttgtga agttgcatgc cccatgggaa gtccttggaa gatatgcaga acaaatgaat      540

gtaagaatgc ctttcaggag aaaaatctat tacctgcccc gccgttacaa gttcatgagc      600

aggatcgata aacaaataag caggtttcgg agatggttac ctaagaagcc aatgaggctg      660

gacaaggaga cactgccaga cctggaggag aatgactgct acactgcccc tttcagccag      720

caaaggatcc atcacttcat catacacaac aaagaaacgt tcttcaacaa tgccacaaga      780

agtagaatcg tgcatcacat tttacaaaga ataaaatatg aagaaggaaa aaacaagatt      840

ggtctgaatc gtttgcttac caatggctcc tatgaagctg cgtttcccct gcatgaggga      900

agttatagaa gtaaaaactc cattcgaacc catggagcag aaaaccaccg acatctactc      960

tatgagtgct gggcctcctg gggcgtgtgg tataaatacc aacctttgga tcttgtaagg     1020

cggtactttg gagagaagat tgggttatat tttgcc                               1056


<210>  5564
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  5564
tgtgtcttct gtcgcctccc agcccacgac ttgtcaggcc gcctggctcg gctctgcagc       60

cagatggagg ccaggcagaa ggaatgtggg gcctccccag acttctcggc ctttgcctta      120

gatgaggtgt ccatgaacaa agtcacagag aagactcaca gagtcctgag ggtcatggaa      180

atcaaagagg ctgtctcctc actcccttca tattggagtt ggcttcgaaa gaccaagctc      240

cctgagtaca ccagggaagc tctctgtccc cccgcctgcc ggggcagcac cacgctgtac      300

aactgctcca cctgcaaggg gacggaggtg tcctgctggc cccgaaagcg ctgcttccca      360

ggaagtcagg atctttggga agccaag                                          387


<210>  5565
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  5565
gcacatttcc gggtctgtga accatacaca gaccacaaag gccgctacca ctttggcttc       60

cactgccccc ggctctcgga caacaagacc ttcatcctct gttgtcacca taacaacacg      120

gtcttcaaat actgctgcaa cgagacggag ttccaggcgg tgatgcaggc gaacctcacg      180

gccagctccg agggttacat gcacaacaat tacacc                                216


<210>  5566
<211>  1383
<212>  DNA
<213>  Homo Sapiens

<400>  5566
gccaaaatcc tgacaatatc tacagtaggt ggaagccatt atctactgat ggaccgggtt       60

tctcagattc ttcaagatca cggtcataat gtcaccatgc ttaaccacaa aagaggtcct      120

tttatgccag attttaaaaa ggaagaaaaa tcatatcaag ttatcagttg gcttgcacct      180

gaagatcatc aaagagaatt taaaaagagt tttgatttct ttctggaaga aactttaggt      240

ggcagaggaa aatttgaaaa cttattaaat gttctagaat acttggcgtt gcagtgcagt      300

cattttttaa atagaaagga tatcatggat tccttaaaga atgagaactt cgacatggtg      360

atagttgaaa cttttgacta ctgtcctttc ctgattgctg agaagcttgg gaagccattt      420

gtggccattc tttccacttc attcggctct ttggaatttg ggctaccaat ccccttgtct      480

tatgttccag tattccgttc cttgctgact gatcacatgg acttctgggg ccgagtgaag      540

aattttctga tgttctttag tttctgcagg aggcaacagc acatgcagtc tacatttgac      600

aacaccatca aggaacattt cacagaaggc tctaggccag ttttgtctca tcttctactg      660

aaagcagagt tgtggttcat taactctgac tttgcctttg attttgctcg acctctgctt      720

cccaacactg tttatgttgg aggcttgatg gaaaaaccta ttaaaccagt accacaagac      780

ttggagaact tcattgccaa gtttggggac tctggttttg tccttgtgac cttgggctcc      840

atggtgaaca cctgtcagaa tccggaaatc ttcaaggaga tgaacaatgc ctttgctcac      900

ctaccccaag gggtgatatg gaagtgtcag tgttctcatt ggcccaaaga tgtccacctg      960

gctgcaaatg tgaaaattgt ggactggctt cctcagagtg acctcctggc tcacccaagc     1020

atccgtctgt ttgtcaccca cggcgggcag aatagcataa tggaggccat ccagcatggt     1080

gtgcccatgg tggggatccc tctctttgga gaccagcctg aaaacatggt ccgagtagaa     1140

gccaaaaagt ttggtgtttc tattcagtta aagaagctca aggcagagac attggctctt     1200

aagatgaaac aaatcatgga agacaagaga tacaagtccg cggcagtggc tgccagtgtc     1260

atcctgcgct cccacccgct cagccccaca cagcggctgg tgggctggat tgaccacgtc     1320

ctccagacag ggggcgcgac gcacctcaag ccctatgtct ttcagcagcc ctggcatgag     1380

cag                                                                   1383


<210>  5567
<211>  624
<212>  DNA
<213>  Homo Sapiens

<400>  5567
ggcttccaag ggacagcagc catctggcca tccctcttca acgtcaactt gtccaagaag       60

gttcaggaaa gcatccagat cccgaacaat gggagtgcgc ccctgctcgt ggatgtgcgg      120

gtgtttgtct ccaacgtgtt taatgtggac atcctgcgat acacaatgtc ctccatgctg      180

ctgcttaggc tgtcctggct ggacactcgc ctggcctgga acactagtgc acacccgcgg      240

cacgccatca cgctgccctg ggagtctctc tggacaccaa ggctcaccat cctggaggcg      300

ctctgggtgg actggaggga ccagagcccc caggctcgag tagaccagga cggccacgtg      360

aagctcaacc tggccctcac cacggagacc aactgcaact ttgagctcct ccacttcccc      420

cgggaccaca gcaactgcag cctcagcttc tacgctctca gcaacacggc gatggagtta      480

gagttccagg cccacgtggt gaacgagatt gtgagtgtca agagggaata cgtagtttat      540

gatctgaaga cccaagtccc accccagcag ctggtgccct gcttccaggt gacgctgagg      600

ctgaagaaca cggcgctcaa gtcc                                             624


<210>  5568
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  5568
gcagcgggcc caaaccgatg tgacaccata taccagggct tcgccgagtg tctcatccgc       60

ttgggggaca gcatgggccg cggaggcgag ctggagacca tctgcaggtc ttggaatgac      120

ttccatgcct gtgcctctca ggtcctgtca ggctgtccgg aggaggcagc tgcagtgtgg      180

gaatcactac agcaagaagc tcgccaggcc ccccgtccga ataacttgca cactctgtgc      240

ggtgccccgg tgcatgttcg ggagcgcggc acaggctccg aaaccaacca ggagacgctg      300

cgggctacag cg                                                          312


<210>  5569
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  5569
aaacctctgc agtccgatga atatgcattg ctaaccagaa atgtggagag agataaatat       60

gcaaatttca ctattaactt tacaatggaa aatcagattc atactggaat ggaatacgac      120

aatggcagat tcataggggt caagttcaaa tctgtaactt tcaaagactc tgtttttaag      180

tcctgcacct ttgaggatgt aacttcagtg aacacctact tcaagaactg cacatttatt      240

gacactgttt ttgacaacac agattttgag ccatataaat tcattgacag tgaatttaaa      300

aactgctcgt tttttcacaa caagacggga tgtcagatta cctttgatga tgactatagt      360


<210>  5570
<211>  489
<212>  DNA
<213>  Homo Sapiens

<400>  5570
cagggccagg aggccggggg gcggccaggg gccgactgtg aagtatgtaa agaattcttg       60

aaccgattct acaagtcact gatagacaga ggagttaact tttcgctgga cactatagag      120

aaagaattga tcagtttttg cttggacacc aaaggaaaag aaaaccgcct gtgctattat      180

ctaggagcca caaaagacgc agccacaaag atcctaagtg aagtcactcg cccaatgagt      240

gtgcatatgc ctgcaatgaa gatttgtgag aagctgaaga agttggatag ccagatctgt      300

gagctgaaat atgaaaaaac actggacttg gcatcagttg acctgcggaa gatgagagtg      360

gcagagctga agcagatcct gcatagctgg ggggaggagt gcagggcctg tgcagaaaaa      420

actgactatg tgaatctcat tcaagagctg gcccccaagt atgcagcgac acaccccaaa      480

acagagctc                                                              489


<210>  5571
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5571
tgcctggata tcgataaact gcttgcgaat gttgtgtttg atgtgtccca agacctcctg       60

aaggaggagc ttgctcgtta caaccccagt cccctgacag aggagtcctt cctcaatgtc      120

cagcaatgct ttgccaatgt ctccgtgaca gaaagatttg ctcattcagt tgttattaag      180

aagatccttc agagcaacga ttgcatagaa gcagccttc                             219


<210>  5572
<211>  291
<212>  DNA
<213>  Homo Sapiens

<400>  5572
aagggcaaat ttgtaggcta tccaggagac ccagtttatt ggttgggaaa atacagaaat       60

gaagagtgtg acccaggtgg ctgtcttctt gaactgacaa ctcagctgac aataatcatg      120

ggaggaaaag caatctggaa taacatacaa gaagtattat tgccctggat catgaatcta      180

attgggcgat ttcacagagt ttctggatca gaaaagataa ccccacgatg ggaacaggac      240

taccatctgc agcctatggg caaactggga ttattttatg aatatcttga a               291


<210>  5573
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  5573
atggcttctc acaacaccct gcagaacttc actgctgcca tccctaccca ccactgccgc       60

ccgcctgccg atgccaacct cagcaagaac ggggggctgg aggtctggct gccccgggac      120

aggcaggggc agcctgagtc ctgcctccgc ttcacctccc cgcagtgggg actgcccttt      180

ctcaatggca cagaagccaa tggcacaggg gccacagagc cctgcaccga tggctggatc      240

tatgacaaca gcaccttccc atctaccatc gtgactgagt gggaccttgt gtgctctcac      300

agggccctac gccag                                                       315


<210>  5574
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  5574
gaactgatgc catctggtgc gattctacag aataagagag aaaatttacc cagagtgtgc       60

catgcactgg cttttctggg aatggcaagg tgccaggatt tgtttttggt tcgcttgcag      120

gggtggaaac ttggaactag gttccaagat ggtccccgca gcaccccaca agaagaagga      180

ggaagcccac agagaaaacg gggcatgcca gttcaaatcc acttcctttt aaagagcttc      240

ctcagcagcc caataacttt tgccttcatc tcattggcca gaactgtgtc attggctact      300

gctatctgca agattgtc                                                    318


<210>  5575
<211>  606
<212>  DNA
<213>  Homo Sapiens

<400>  5575
atgtgcttcc ggacaaagct ctcagtatcc tgggtgccat tgtttcttct actcagccgt       60

gttttttcta ctgagacaga caaaccctca gcccaggaca gcagaagccg tgggagttca      120

ggccaaccgg cagacctgct acaggttctc tctgctggtg accacccacc ccacaaccac      180

tcaagaagcc tcatcaaaac attgttggag aaaactgggt gcccacggag gagaaacgga      240

atgcaaggag attgcaatct gtgctttgaa ccagatgcac tattactaat agctggagga      300

aattttgaag atcagcttag agaagaagtg gtccagagag tttctcttct ccttctctat      360

tacattattc atcaggaaga gatctgttct tcaaagctca acatgagtaa taaagagtat      420

aaattttacc tacacagcct actgagcctc aggcaggatg aagattcctc tttcctttca      480

cagaatgaga cagaagatat cttggctttc accaggcagt actttgacac ttctcaaagc      540

cagtgtatgg aaaccaaaac gctgcagaaa aaatctggaa tagtgagcag tgaaggtgct      600

aatgaa                                                                 606


<210>  5576
<211>  2718
<212>  DNA
<213>  Homo Sapiens

<400>  5576
ctctctttag aggccccaac cgtggggaaa ggacaagccc caggcatcga ggagacagat       60

ggcgagctga cagcagcccc cacacctgag cagccagaac gaggcgtcca ctttgtcaca      120

acagccccca ccttgaagct gctcaaccac cacccgctgc ttgaggaatt cctacaagag      180

gggctggaaa agggagatga ggagctgagg ccagcactgc ccttccagcc tgacccacct      240

gcacccttca ccccaagtcc ccttccccgc ctggccaacc aggacagccg ccctgtcttt      300

accagcccca ctccagccat ggctgcggta cccactcagc cccagtccaa ggagggaccc      360

tggagtccgg agtcagagtc ccctatgctt cgaatcacag ctcccctacc tccagggccc      420

agcatggcag tgcccaccct aggcccaggg gagatagcca gcactacacc ccccagcaga      480

gcctggacac caacccaaga gggtcctgga gacatgggaa ggccgtgggt tgcagaggtt      540

gtgtcccagg gcgcagggat cgggatccag gggaccatca cctcctccac agcttcagga      600

gatgatgagg agaccaccac taccaccacc atcatcacca ccaccatcac cacagtccag      660

acaccaggcc cttgtagctg gaatttctca ggcccagagg gctctctgga ctcccctaca      720

gacctcagct cccccactga tgttggcctg gactgcttct tctacatctc tgtctaccct      780

ggctatggcg tggaaatcaa ggtccagaat atcagcctcc gggaagggga gacagtgact      840

gtggaaggcc tgggggggcc tgacccactg cccctggcca accagtcttt cctgctgcgg      900

ggccaagtca tccgcagccc cacccaccaa gcggccctga ggttccagag cctcccgcca      960

ccggctggcc ctggcacctt ccatttccat taccaagcct atctcctgag ctgccacttt     1020

ccccgtcgtc cagcttatgg agatgtgact gtcaccagcc tccacccagg gggtagtgcc     1080

cgcttccatt gtgccactgg ctaccagctg aagggcgcca ggcatctcac ctgtctcaat     1140

gccacccagc ccttctggga ttcaaaggag cccgtctgca tcggtgagtg cccaggggtg     1200

atccgcaatg ccaccaccgg ccgcatcgtc tctccaggct tcccgggcaa ctacagcaac     1260

aacctcacct gtcactggct gcttgaggct cctgagggcc agcggctaca cctgcacttt     1320

gagaaggttt ccctggcaga ggatgatgac aggctcatca ttcgcaatgg ggacaacgtg     1380

gaggccccac cagtgtatga ttcctatgag gtggaatacc tgcccattga gggcctgctc     1440

agctctggca aacacttctt tgttgagctc agtactgaca gcagcggggc agctgcaggc     1500

atggccctgc gctatgaggc cttccagcag ggccattgct atgagccctt tgtcaaatac     1560

ggtaacttca gcagcagcac acccacctac cctgtgggta ccactgtgga gttcagctgc     1620

gaccctggct acaccctgga gcagggctcc atcatcatcg agtgtgttga cccccacgac     1680

ccccagtgga atgagacaga gccagcctgc cgagccgtgt gcagcgggga gatcacagac     1740

tcggctggcg tggtactctc tcccaactgg ccagagccct acggtcgtgg gcaggattgt     1800

atctggggtg tgcatgtgga agaggacaag cgcatcatgc tggacatccg agtgctgcgc     1860

ataggccctg gtgatgtgct taccttctat gatggggatg acctgacggc ccgggttctg     1920

ggccagtact cagggccccg tagccacttc aagctcttta cctccatggc tgatgtcacc     1980

attcagttcc agtcggaccc cgggacctca gtgctgggct accagcaggg cttcgtcatc     2040

cacttctttg aggtgccccg caatgacaca tgtccggagc tgcctgagat ccccaatggc     2100

tggaagagcc catcgcagcc tgagctagtg cacggcaccg tggtcactta ccagtgctac     2160

cctggctacc aggtagtggg atccagtgtc ctcatgtgcc agtgggacct aacttggagt     2220

gaggacctgc cctcatgcca gagggtgact tcctgccacg atcctggaga tgtggagcac     2280

agccgacgcc tcatatccag ccccaagttt cccgtggggg ccaccgtgca atatatctgt     2340

gaccagggtt ttgtgctgat gggcagctcc atcctcacct gccatgatcg ccaggctggc     2400

agccccaagt ggagtgaccg ggcccctaaa tgtctcctgg aacagctcaa gccatgccat     2460

ggtctcagtg cccctgagaa tggtgcccga agtcctgaga agcagctaca cccagcaggg     2520

gccaccatcc acttctcgtg tgcccctggc tatgtgctga agggccaggc cagcatcaag     2580

tgtgtgcctg ggcacccctc gcattggagt gaccccccac ccatctgtag ggctgcctct     2640

ctggatgggt tctacaacag tcgcagcctg gatgttgcca aggcacctgc tgcctccagc     2700

accctggatg ctgcccac                                                   2718


<210>  5577
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  5577
gatgcacctc ctaccccaca gccaaagtgc gctgacttcc agagcgccaa cctttttgaa       60

ggcaccgatc tcaaagtcca gtttctcctc tttgtccctt cgaatcctag ctgtgggcag      120

ctagtagaag gaagcagtga cctccaaaac tctgggttca atgccactct gggaaccaaa      180

ctaattatcc atggattcag ggttttagga acaaagcctt cctggattga cacatttatt      240

agaacccttc tgcgtgcaac gaatgctaat gtgattgccg tggactggat ttatgggtct      300

acaggagtct acttctcagc tgtgaaaaat gtgctgggtg tgtcggaatc ctcaatccac      360

atcattggtg ttagcctggg ggcccacgtt gggggcatgg tgggacagct cttcggaggc      420

cagctgggac agatcacagg cctggacccc gctggacctg agtacaccag ggccagtgtg      480

gaagagcgct tggatgctgg agatgccctc ttcgtggaag ccatccacac agacaccgac      540

aatttgggta ttcggattcc cgttggacat gtggactact tcgtcaacgg aggccaagac      600

caacctggct gccccacctt cttttacgca ggttatagtt atctgatctg tgatcacatg      660

agggctgtgc acctctacat cagcgccctg gagaattcct gtccactgat ggcctttccc      720

tgtgccagct acaaggcctt ccttgctgga cgctgtctgg attgctttaa cccttttctg      780

ctttcctgcc caaggatagg actggtggaa caaggtggtg tcaagataga gccgctcccc      840

aaggaagtga aagtctacct cctgactact tccagtgctc cgtactgcat gcatcacagc      900

ctcgtggagt ttcacttgaa ggaactgaga aacaaggaca ccaacatcga ggttaccttc      960

cttagcagta acatcacctc ttcatctaag atcaccatac ctaagcagca acgctatggg     1020

aaaggaatca tagcccatgc caccccacaa tgccagataa accaagtgaa attcaagttt     1080

cagtcttcca accgagtttg gaaaaaagac cggactacca ttattgggaa gttctgcact     1140

gcccttttgc ctgtcaatga cagagaaaag atggtctgct tacctgaacc agtgaactta     1200

caagcaagtg tgactgtttc ctgtgacctg aagatagcct gtgtg                     1245


<210>  5578
<211>  801
<212>  DNA
<213>  Homo Sapiens

<400>  5578
gaggttccag aggagagcag caggatggcc gggagcggag ccaggagtga ggaaggccgc       60

cggcagcatg ccttcgtccc ggaacctttt gatggggcca atgtcgtccc aaacctctgg      120

ctgcacagct ttgaagtcat caatgacctc aaccattggg accatatcac caagctaagg      180

ttcctgaaag agtccctcag aggagaggcc ctgggtgtct acaataggct cagtccccag      240

gaccagggag actatgggac tgtgaaagag gccctcctga aggcctttgg ggtccctggg      300

gctgccccca gccacctgcc caaagagatc gtctttgcca acagcatggg taagggctac      360

tatctcaagg ggaagattgg caaagtgccc gtgaggttcc tggtggactc tggggcccag      420

gtctctgtgg tccacccaaa cttgtgggag gaggtcactg atggcgatct ggacaccctg      480

cagccctttg agaatgtggt aaaggtggcc aatggtgctg aaatgaagat cctgggtgtc      540

tgggatacag cggtgtccct aggcaagctg aagctgaagg cacagttcct agtggccaat      600

gcgagtgccg aggaagccat cattggcact gatgtgctcc aggaccacaa tgctatcctg      660

gactttgagc accgcacatg caccctgaaa gggaagaagt ttcgccttct gcctgtggga      720

gggtccctgg aagatgagtt tgacctggag ctcatagagg aggacccctc ctcagaagaa      780

gggcggcagg agctatccca c                                                801


<210>  5579
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  5579
atagaatgtg ccaaacagac gaaacagatg gttgactgca gtcattataa aaagttacca       60

ccaggacaac agagattttg tcatcatatg tatgatccaa tttgtggatc tgatggcaaa      120

acttataaaa atgattgctt cttctgttct aaagttaaga aaactgacgg cacacttaaa      180

tttgtacatt ttggaaaatg t                                                201


<210>  5580
<211>  420
<212>  DNA
<213>  Homo Sapiens

<400>  5580
atggacagcc ggattcctta tgatgactac ccggtggttt tcttgcctgc ctatgagaat       60

cctccagcat ggattcctcc tcatgagagg gtacaccacc cggactacaa caatgagttg      120

acccagtttc tgccccgaac catcacactg aagaagcctc ctggagctca gttgggattt      180

aacatccgag gaggaaaggc ctcccagcta ggcatcttca tctccaaggt gattcctgac      240

tctgatgcac atagagcagg actgcaggaa ggggaccaag ttctagctgt gaatgatgtg      300

gatttccaag atattgagca cagcaaggct gttgagatcc tgaagacagc tcgtgaaatc      360

agcatgcgtg tgcgcttctt tccctacaat tatcatcgcc aaaaagagag gactgtgcac      420


<210>  5581
<211>  1341
<212>  DNA
<213>  Homo Sapiens

<400>  5581
aggggctttc ccaggccact tgaaaactcc gaaatcccta tgatccctgg agcccacccc       60

aagggctctg tgggctcaga gccccaggcc tttgacgtgt tcccggagaa ccccagagct      120

gacagtcaca ggaactctga tgtccgccac gcccctgctg aagagatgcc tgagaagcct      180

gtagcctctc cccttggccc agccctgtac gggcccaaag cagcacaagg agctcagaga      240

gaacgactcc cagtaactga tgacctccag atggctcaag gaccaagctc ccacggctgg      300

acaggacctc tggactcaca agagcttctg gagcaagaag cagtggctcc ccacccagtg      360

ggccaccctc atctcacttt catccccaca actcccagac gtcaactcag ggtagccaca      420

gttcctccct ccctgcagca tgaaggccaa gagggacagt ggccacctag agatgagggt      480

ctgaaggcca aaactaagag cagggtccca cccacttctc cctcagacca ccagggccca      540

ccccacaccc ttgtttccca ctcaggtact gtcaagaggc cagtgctgga aggacagggt      600

gggtttgagg aacacttgca ggaggcagct caaggtcccc acttcaccca gcaggatcca      660

gcagcccctg atgttggctc agtaccccca gttgaggtgg tgtactctca ggagccaggg      720

gcccagccag acttggcatt ggccagaagc cttcctcctg ctgaggagct gccggttgag      780

acccccaaga gggctggcgc tgaggtgtcc tgggaagtca gctccccagg tcccccgccc      840

aagcaggctg accttcctga cgctaaggat tcaccaggac cccagcccac ggatccaccc      900

gcctcagagg ctcctgatcg gccgtctaag ccagagagag cagcaatgaa tggagcagac      960

cccatctccc cccagcgggt gagaggagct gtggaggccc caggcacccc caagtctctc     1020

atccctggtc cctcagaccc tggcccagct gtaaaccgaa cagagagccc catgggggcc     1080

ctgcagccag atgaagccga ggagtggccg gggcgccccc aaagccatcc cccagcaccc     1140

ccagtccagg cgccctcgac gtcacgccgg ggcctcattc gagtcaccac gcagcgagcc     1200

ctgggccagc ctccccctcc ggagcccacc gccagctcca tggcttcagc cccagcctcc     1260

agccccccag ccaacgccac tgcacccccg ctacgctggg gcccccttcg gcgggtcctg     1320

agcttctcct gggagctgca c                                               1341


<210>  5582
<211>  1650
<212>  DNA
<213>  Homo Sapiens

<400>  5582
ttagaagagg aggaagaagg ggccttacta gctcaagctg gagagaaact agagcccagc       60

acaacttcca cctcccagcc ccatctcatt ttcatcctag cggatgatca gggatttaga      120

gatgtgggtt accacggatc tgagattaaa acacctactc ttgacaagct cgctgccgaa      180

ggagttaaac tggagaacta ctatgtccag cctatttgca caccatccag gagtcagttt      240

attactggaa agtatcagat acacaccgga cttcaacatt ctatcataag acctacccaa      300

cccaactgtt tacctctgga caatgccacc ctacctcaga aactgaagga ggttggatat      360

tcaacgcata tggtcggaaa atggcacttg ggtttttaca gaaaagaatg catgcccacc      420

agaagaggat ttgatacctt ttttggttcc cttttgggaa gtggggatta ctatacacac      480

tacaaatgtg acagtcctgg gatgtgtggc tatgacttgt atgaaaacga caatgctgcc      540

tgggactatg acaatggcat atactccaca cagatgtaca ctcagagagt acagcaaatc      600

ttagcttccc ataaccccac aaagcctata tttttatata ttgcctatca agctgttcat      660

tcaccactgc aagctcctgg caggtatttc gaacactacc gatccattat caacataaac      720

aggaggagat atgctgccat gctttcctgc ttagatgaag caatcaacaa cgtgacattg      780

gctctaaaga cttatggttt ctataacaac agcattatca tttactcttc agataatggt      840

ggccagccta cggcaggagg gagtaactgg cctctcagag gtagcaaagg aacatattgg      900

gaaggaggga tccgggctgt aggctttgtg catagcccac ttctgaaaaa caagggaaca      960

gtgtgtaagg aacttgtgca catcactgac tggtacccca ctctcatttc actggctgaa     1020

ggacagattg atgaggacat tcaactagat ggctatgata tctgggagac cataagtgag     1080

ggtcttcgct caccccgagt agatattttg cataacattg accccatata caccaaggca     1140

aaaaatggct cctgggcagc aggctatggg atctggaaca ctgcaatcca gtcagccatc     1200

agagtgcagc actggaaatt gcttacagga aatcctggct acagcgactg ggtcccccct     1260

cagtctttca gcaacctggg accgaaccgg tggcacaatg aacggatcac cttgtcaact     1320

ggcaaaagtg tatggctttt caacatcaca gccgacccat atgagagggt ggacctatct     1380

aacaggtatc caggaatcgt gaagaagctc ctacggaggc tctcacagtt caacaaaact     1440

gcagtgccgg tcaggtatcc ccccaaagac cccagaagta accctaggct caatggaggg     1500

gtctggggac catggtataa agaggaaacc aagaaaaaga agccaagcaa aaatcaggct     1560

gagaaaaagc aaaagaaaag caaaaaaaag aagaagaaac agcagaaagc agtctcaggt     1620

tcaacttgcc attcaggtgt tacttgtgga                                      1650


<210>  5583
<211>  1638
<212>  DNA
<213>  Homo Sapiens

<400>  5583
aagccgagct tcgtggccga cgggcccggg gaggctggcg agcagccctc ggccgctccg       60

ccccagcctc cccacatcat cttcatcctc acggacgacc aaggctacca cgacgtgggc      120

taccatggtt cagatatcga gacccctacg ctggacaggc tggcggccaa gggggtcaag      180

ttggagaatt attacatcca gcccatctgc acgccttcgc ggagccagct cctcactggc      240

aggtaccaga tccacacagg actccagcat tccatcatcc gcccacagca gcccaactgc      300

ctgcccctgg accaggtgac actgccacag aagctgcagg aggcaggtta ttccacccat      360

atggtgggca agtggcacct gggcttctac cggaaggagt gtctgcccac ccgtcggggc      420

ttcgacacct tcctgggctc gctcacgggc aatgtggact attacaccta tgacaactgt      480

gatggcccag gcgtgtgcgg cttcgacctg cacgagggtg agaatgtggc ctgggggctc      540

agcggccagt actccactat gctttacgcc cagcgcgcca gccatatcct ggccagccac      600

agccctcagc gtcccctctt cctctatgtg gccttccagg cagtacacac acccctgcag      660

tcccctcgtg agtacctgta ccgctaccgc accatgggca atgtggcccg gcggaagtac      720

gcggccatgg tgacctgcat ggatgaggct gtgcgcaaca tcacctgggc cctcaagcgc      780

tacggtttct acaacaacag tgtcatcatc ttctccagtg acaatggtgg ccagactttc      840

tcggggggca gcaactggcc gctccgagga cgcaagggca cttattggga aggtggcgtg      900

cggggcctag gctttgtcca cagtcccctg ctcaagcgaa agcaacggac aagccgggca      960

ctgatgcaca tcactgactg gtacccgacc ctggtgggtc tggcaggtgg taccacctca     1020

gcagccgatg ggctagatgg ctacgacgtg tggccggcca tcagcgaggg ccgggcctca     1080

ccacgcacgg agatcctgca caacattgac ccactctaca accatgccca gcatggctcc     1140

ctggagggcg gctttggcat ctggaacacc gccgtgcagg ctgccatccg cgtgggtgag     1200

tggaagctgc tgacaggaga ccccggctat ggcgattgga tcccaccgca gacactggcc     1260

accttcccgg gtagctggtg gaacctggaa cgaatggcca gtgtccgcca ggccgtgtgg     1320

ctcttcaaca tcagtgctga cccttatgaa cgggaggacc tggctggcca gcggcctgat     1380

gtggtccgca ccctgctggc tcgcctggcc gaatataacc gcacagccat cccggtacgc     1440

tacccagctg agaacccccg ggctcatcct gactttaatg ggggtgcttg ggggccctgg     1500

gccagtgatg aggaagagga ggaagaggaa gggagggctc gaagcttctc ccggggtcgt     1560

cgcaagaaaa aatgcaagat ttgcaagctt cgatcctttt tccgtaaact caacaccagg     1620

ctaatgtccc aacggatc                                                   1638


<210>  5584
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  5584
atggacatca agatgcagat tggcagcagg aacttctata ccttaagcat tgactatccc       60

agggttaact acccaaaggg tttccggggc tattgtaatg gtctgatgtc ctatatgcga      120

ggcaagatgc aaaattcaga ttgcccaaag atccattatg tgatacatgc cccttggaag      180

gccatccaga agttctgcaa gtatagtgac agcttctgtg agaattacaa tgaatactgc      240

acactcaccc aggattccct ccccatcacg gtctgctccc tgagccacca acagccaccc      300

actagctgct actacaatag caccctaacc aaccagaagc tctacctact ctgctcccgc      360

aagtatgaag ctgatccaat aggtatcgct ggtctctatt cgggaatt                   408


<210>  5585
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5585
gaagcagtga tgtcaacttt agaacacttg catgtggact accctcagaa tgacgttccc       60

gttcctgcaa ggtactgcaa ccacatgatc atacaaagag ttatcaggga acctgaccac      120

acttgtaaaa aggagcatgt cttcatccat gagaggcctc gaaaaatcaa tggtatttgc      180

atttctccca agaaggttgc ttgccaaaac ctttcggcca ttttctgctt tcagagtgag      240

acaaagttca aaatgacagt ctgtcagctc attgaaggca caagataccc tgcctgcagg      300

taccactatt cccccacaga ggggtttgtt cttgtcactt gtgatgactt gaggccagat      360

agtttccttg gctatgttaa a                                                381


<210>  5586
<211>  570
<212>  DNA
<213>  Homo Sapiens

<400>  5586
cttcatatgg ctacagcagt cttggaggag agtgatcaac cgctcaatga attttggtcc       60

agtgactcac aggacaaagc tgaggccact gaggagggag acggcaccca aaccacagaa      120

acgctggtgc ttagcaacaa agaagtggtg caacctggct ggccagaaga tcccatcctc      180

ggtgaagatg aggttggggg taacaagatg ctcagagcct cagctctctt tcagagcaac      240

aaagactatc ttaggcttga ccagacagat agagaatgca atgatatgat ggcacacaag      300

atgaaggagc ccagtcagag ttgcatagcc cagtatgcat tcatccatga ggatctaaac      360

acagtcaaag ctgtctgtaa cagtcctgtc attgcctgtg agctcaaggg gggaaaatgt      420

cacaaaagct cccgaccttt tgatttgaca ttgtgcgagc tgtcccaacc agaccaggtc      480

actcctaact gcaattacct aacttctgtt ataaaaaagc acattattat aacctgtaat      540

gacatgaagc gccagttacc aactggacaa                                       570


<210>  5587
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  5587
caggtcaccc cagtcatgaa atgttggggc aagtcaggca ggtgcagaac aacatgtaaa       60

gaaagtgaag tatactatat attatgcaaa actgaggcta agtgctgtgt ggatcccaag      120

tatgtacctg taaaaccaaa attaacagac acaaatacaa gcctggaatc aacttctgca      180

gtc                                                                    183


<210>  5588
<211>  966
<212>  DNA
<213>  Homo Sapiens

<400>  5588
ggctctccag ttttgaggaa ctttactttt gcagtttcct ggagaactga gaaaattctt       60

taccggctgg atgtgggttg gcctaagcac ccagaatatt ttaccggaac aacattttgt      120

gttgcagttg actccctcaa tggattggtt tacataggtc aaagagggga taacatccca      180

aagatattag tgttcacaga ggatggatat ttcctacgag cctggaatta tacagttgac      240

acacctcatg gtatatttgc agccagtact ctatatgaac aatccgtctg gatcacggat      300

gtaggaagtg gattctttgg tcatactgtt aaaaaataca gttcttttgg tgatcttgtt      360

caagtcttgg gtactccagg caaaaaaggc actagtttga atcctttgca gtttgataac      420

ccagcagaat tatatgtaga ggacacagga gatatttaca ttgtggatgg agatggagga      480

ttgaataaca gattgatcaa actgtcccaa gatttcatga tcctttggct gcatggagaa      540

aatgggacag ggcctgctaa gttcaacata cctcacagtg ttacacttga ttcagctggt      600

cgggtgtggg ttgctgaccg aggaaataaa agaatccaag tatttgataa agacactggg      660

gagtggttag gagcatggaa taattgtttc acagaagagg gaccttcttc agtcaggttt      720

actcctgatg ggaagtactt gattgtggcc cagctgaatc ttagcaggct ctcagtcgta      780

gcagcacccc cagtgggaag cattggggag tgttctgtga tcagcacaat ccaactagca      840

gatcaagttt tgccacatct cctagaagtc gacagaaaga ctggagcagt ctatgtagca      900

gaaattggag caaaacaagt acaaaaatat gtccctttga atagctatgt tccttcattt      960

ggttca                                                                 966


<210>  5589
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  5589
gccgaaccct tcagccctcc gcgaggagac tcagctcaga gcacagcgtg tgacagacac       60

atggctgtgc aacgccgtct agatgtcatg gaggagatgg tagagaagac cgtggatcac      120

ctggggacag aggtgaaagg cctgctgggc ctgctggagg agctggcctg gaacctgccc      180

ccgggaccct tcagccccgc tcccgacctt ctcggagatg gcttc                      225


<210>  5590
<211>  1215
<212>  DNA
<213>  Homo Sapiens

<400>  5590
gtggaggcca ccagcgtgct cctgcccaca gacatcaagt ttgggatcgt gtttgatgcg       60

ggctcctccc acacgtccct cttcctgtat cagtggctgg cgaacaagga gaatggcacg      120

ggtgtggtca gccaggccct ggcctgccag gtggaagggc ctggaatctc ctcctacact      180

tctaatgctg cacaggctgg tgagagcctg cagggctgct tggaggaggc gctggtgctg      240

atcccagagg cccagcatcg gaaaacaccc acgttcctgg gggccacggc tggcatgagg      300

ttgctcagcc ggaagaacag ctctcaggcc agggacatct ttgcagcagt cacccaggtc      360

ctgggccggt ctcccgtgga cttttggggt gccgagctcc tggccgggca ggccgaaggt      420

gcctttggtt ggatcactgt caactacggc ttggggacgc tggtcaagta ctccttcact      480

ggagaatgga tccagcctcc ggaggagatg ctggtgggtg ccctggacat gggaggggcc      540

tccacccaga tcacgttcgt gcctgggggc cccatcttgg acaagagcac ccaggccgat      600

tttcgcctct acggctccga ctacagcgtc tacactcaca gctacctgtg ctttggacgg      660

gaccagatgc tgagcaggct cctcgtgggg ctggtacaga gccgcccggc tgccctgctc      720

cgtcacccgt gctacctcag cggctaccag accacactgg ccctgggccc gctgtatgag      780

tcaccctgtg tccacgccac gcccccgctg agcctccccc agaacctcac agttgaaggg      840

acaggcaacc ctggagcctg cgtctcagcc atccgggaac ttttcaactt ctccagctgc      900

cagggccagg aggactgcgc ctttgacggg gtctaccagc ccccgctgcg gggccagttc      960

tatgtggagg ccagctaccc tgggcaggac cgctggctgc gggactactg tgcctcaggc     1020

ctgtacatcc tcaccctcct gcacgagggc tacgggttca gcgaggagac ctggcccagc     1080

ctcgagttcc gaaagcaggc gggcggtgtg gacattggct ggacactggg ctacatgctg     1140

aacctgaccg ggatgatccc ggccgatgcg ccggctcagt ggcgggcaga gagctacggc     1200

gtctgggtgg ccaaa                                                      1215


<210>  5591
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5591
aggatgtcat cgctcagttt tctgaatata gagaagactg aaatactatt tttcacaaag       60

actgaagaaa ccatccttgt aagttcaagc tacgaaaata aacggcctaa ttccagccac      120

ctctttgtga aaatagaaga tcctaaaata ctacaaatgg tgaatgtggc caagaagatc      180

tcatcagatg ctacaaactt taccataaat ctggtgactg atgaagaagg agaaacaaat      240

gtgactattc aactctggga ttctgaaggt aggcaagaaa gactcattga agaaatcaag      300

aatgtgaaag tcaaagtgct caaacaaaaa gacagtctac tccaggcacc aatgcatatt      360

gatagaaac                                                              369


<210>  5592
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5592
gacccccggg acctcaagag ctgtaaccgc ccctgtgtgt ggtcgaggct tttgaaacca       60

aactctagcc tctccaacct agaaactgca tactttccac aaaatttgag atttttgaga      120

ccctggtact tttcacgaag tcaccttaat tatcaccaaa aagctcctgc aagatgggag      180

tggttatact ccatttacag gaaaggaacc aaggctcaga gaagaaatgt gctccgttca      240

ccgtgtgctc ctcctcagcc atcctggccg tgctcagtca tc                         282


<210>  5593
<211>  2679
<212>  DNA
<213>  Homo Sapiens

<400>  5593
gccactgagg ctcgtctgca cccggagggc agcagcagaa agcagcagcg agctcagtca       60

cccgctagac cgagggacag ttcgctgcga cagacaatcg cggccacccg gtccccagtg      120

ggggccggca ctaaactcaa ttctgttcgg cagcagcagc tgcagcagca gcaacagcag      180

ggtaacaaga ccgggagccg cacggggccg cccgccagca tccgaggagg cggaggtggg      240

gccgagaagg cgacgcccct ggcgcccaaa ggggccgctc cgggagctgt ccagcctgtg      300

gctggtgctg aagcggcccc cgccgcgacc ctggccgctt tgggcggcag gaggcccgga      360

ccgcccgagg agccgcctcg ggagctagag tccgtgccct cgaaactcgg ggaaccccct      420

ccgctcggag aagggggagg agggggcggg gaaggaggag gagccggcgg cggctccggg      480

gaaagggagg ggggcgctcc gcagccgccg ccgcccaggg gctggcgagg gaaaggcgta      540

cgcgctcagc agaggggcgg cagcggcggg gagggggcct ccccttctcc atcctcctct      600

tctgcgggca aaaccccagg aaccggcagc agaaactccg gaagcggcgt tgcggggggc      660

ggcagcggtg gtggagggag ctactggaaa gaaggatgtc tgcagtctga gctcatccag      720

ttccatctca agaaggagcg ggcggcagcg gcggcggccg cggctcagat gcacgctaag      780

aacggcggcg gcagcagtag ccgcagctcc ccggtgtctg gcccccctgc cgtttgcgag      840

accctggccg tcgcctccgc ctccccaatg gcggcggcgg cggagggccc ccagcagagc      900

gcagagggca gcgcgagcgg cgggggcatg caggcggcag cgcccccttc gtcgcagccg      960

cacccgcagc agctccaaga gcaggaagaa atgcaagagg agatggagaa gctgcgagag     1020

gaaaacgaga ctctcaagaa cgagatcgat gagctgagaa ccgagatgga cgagatgagg     1080

gacactttct tcgaggagga tgcctgtcaa ctgcaggaaa tgcgccacga gttggagaga     1140

gccaacaaaa actgccggat cctgcagtac cgcctccgca aagccgagcg caaaaggctc     1200

cgctacgccc agaccgggga aatcgacggg gagctgttgc gcagcctgga gcaggacctc     1260

aaggttgcaa aggatgtatc tgtgagactt caccatgaat tagaaaatgt ggaagaaaag     1320

agaacaacaa cagaagatga aaatgagaaa ctgaggcaac agctcataga agttgaaatt     1380

gcaaagcaag ctttacagaa tgaactggaa aaaatgaaag agttatcctt aaaaagaaga     1440

ggaagcaaag atttgccaaa atctgaaaaa aaggctcaac agactcccac agaggaggac     1500

aatgaagatc tgaagtgcca gctgcagttt gttaaggaag aagccgcttt gatgagaaag     1560

aaaatggcca agattgataa agaaaaggac agatttgaac acgagctcca gaagtacaga     1620

tccttttatg gggatctgga cagtcctttg cccaaaggag aagccggagg ccctcccagc     1680

actagggagg ccgagctcaa gctacggcta aggctggtgg aggaagaagc caacatcctg     1740

ggcaggaaaa tcgtcgaact ggaggtggag aacagaggcc tgaaggcgga actggacgac     1800

cttaggggcg atgacttcaa cggctcggcc aacccgctca tgagggagca gagcgaatcc     1860

ctgtcggagc tgcggcagca cctgcagctg gtggaagacg agacggagct gctgcggagg     1920

aacgtggccg acctggagga gcagaacaag cgcatcacgg cggagctcaa caagtacaag     1980

tacaagtccg gcggccacga cagcgcgcgg caccacgaca acgccaagac cgaggccctg     2040

caggaggagc tgaaggcggc gcgcctgcag atcaacgagc tcagcggcaa ggtcatgcag     2100

ctgcagtacg agaaccgcgt gcttatgtcc aacatgcagc gctacgacct ggcctcgcac     2160

ctgggcatcc gcggcagccc ccgcgacagc gacgccgaga gcgacgcggg caagaaggag     2220

agcgacgacg actcgcggcc tccgcaccgc aagcgcgaag ggcccatcgg cggcgagagc     2280

gactcggagg aggtgcgcaa catccgctgc ctcacgccca ctcgctcctt ctacccggcg     2340

cccgggccct ggcccaagag cttctccgat cggcagcaga tgaaggacat ccgctcggag     2400

gccgagcgcc tgggcaagac catcgaccgg ctcatcgccg acacgagcac catcatcacc     2460

gaggcgcgca tctacgtggc caacggggac ctgttcggac tcatggacga ggaggacgac     2520

ggcagccgca tccgggagca cgagctgctc taccgcatca acgctcagat gaaggccttc     2580

cgcaaggagc tgcagacctt catcgaccgc ctcgaggtgc ccaagtctgc ggacgaccgc     2640

ggcgccgagg agcccatttc cgtgagtcag atgttccag                            2679


<210>  5594
<211>  582
<212>  DNA
<213>  Homo Sapiens

<400>  5594
agcggctgcc gggccgggac tggtgcgcga ggggctgggg cggaaggtcg agagggcgag       60

gcctgtggca cggtggggct gctgctggag cactcatttg agatcgatga cagtgccaac      120

ttccggaagc ggggctcact gctctggaac cagcaggatg gtaccttgtc cctgtcacag      180

cggcagctca gcgaggagga gcggggccga ctccgggatg tggcagccct gaatggcctg      240

taccgggtcc ggatcccaag gcgacccggg gccctggatg gcctggaagc tggtggctat      300

gtctcctcct ttgtccctgc gtgctccctg gtggagtcgc acctgtcgga ccagctgacc      360

ctgcacgtgg atgtggccgg caacgtggtg ggcgtgtcgg tggtgacgca ccctgggggc      420

tgccggggcc atgaggtgga ggacgtggac ctggagctgt tcaacacctc ggtgcagctg      480

cagccgccca ccacagcccc aggccctgag acggcggcct tcattgagcg cctggagatg      540

gaacaggccc agaaggccaa gaacccccag gagcagaagt cc                         582


<210>  5595
<211>  1140
<212>  DNA
<213>  Homo Sapiens

<400>  5595
tatgacaaga aaggaaacaa tgcaaaccct gaagctaata tgaatattag ccagattatt       60

tcttactggg gttatcctta tgaagagtat gatgttacaa caaaagatgg ttatatcctt      120

ggaatttata ggattccaca tggaagagga tgcccaggga ggacagctcc aaagcctgct      180

gtgtatttgc agcatggctt aattgcatct gccagtaact ggatttgcaa cctgcccaac      240

aacagtttgg ctttccttct ggcagatagt ggttatgacg tgtggttggg gaacagccga      300

ggaaacactt ggtccagaaa acaccttaaa ttgtcaccga aatcaccgga atactgggcc      360

ttcagtttgg atgagatggc taaatatgac cttccagcca caatcaattt tatcatagag      420

aaaactggac agaagcgact ctactacgtg ggccactcac aaggcaccac catagctttt      480

atagcatttt ctacaaaccc agaactggct aaaaagatta agatattttt tgcactggct      540

ccagttgtca cagttaaata cacccaaagt cctatgaaaa aactaacaac cctttccagg      600

cgagtagtta aggtgttgtt tggtgacaaa atgttccacc ctcatacatt gtttgaccaa      660

ttcattgcca ccaaagtgtg caatcgaaag ctattccgtc gtatttgcag caacttccta      720

tttactctga gtggatttga tccgcaaaac ttaaatatga gtcgcttgga tgtttatttg      780

tcacacaatc ctgcgggaac atctgttcag aatatgctgc actgggctca ggctgttaat      840

tctggtcagc tccaagcttt tgattgggga aactctgatc agaacatgat gcacttccat      900

cagcttacac ctcctttata caacattact aagatggaag ttccaacagc aatatggaat      960

ggtggacagg acattgtggc tgatcccaag gatgttgaaa atttacttcc tcaaattgct     1020

aaccttattt attacaagct gattccacac tacaatcatg tggattttta ccttggagag     1080

gatgcacctc aggaaattta ccaagaccta attatattga tggaagaata tttacaaaat     1140


<210>  5596
<211>  1281
<212>  DNA
<213>  Homo Sapiens

<400>  5596
caagccatgg aaggtgtcaa atgtgggggt gtgctctcag caccttctgg aaacttctcc       60

agccccaact tccctagact gtacccctac aacacagagt gcagctggct gatcgtggtg      120

gccgagggat cctcggtgct gctcaccttc catgcctttg acctagagta ccacgacacc      180

tgcagcttcg actttctgga gatctacaat ggggcctcac cagacaaggg caacctgctg      240

gggaggttct gcggcaaggt gcccccgccg cccttcacct cctcctggca tgtcatgtct      300

gtcatcttcc actcggacaa gcatgtggcc agccatggct tttctgcggg ctaccagaaa      360

gatgtgtgtg gcggcgtcct gactggcctg tcaggggtcc tcaccagtcc tgagtatccc      420

aacaactacc cgaacagcat ggagtgccac tgggtgatcc gggccgctgg ccctgcccac      480

gtcaagctgg tgttcgtgga cttccaggtg gagggcaatg aagagtgcac ctatgactac      540

gtggctgtgc ttggggggcc tggccccacc cgtgggcacc actactgtgg cagcaccagg      600

ccccccaccc tcgtgtctct gggccacgaa ctgcaggtgg tcttcaagtc cgacttcaac      660

atcggaggcc gtggcttcaa ggcctactac ttctcaggag aatgccagga ggtatacatg      720

gccatgcggg gcaacttctc cagcccacag taccccagct cctaccccaa caacatccgc      780

tgccactgga ccatccgcct gcccccgggc taccaggtca aggtgttctt cctggacctg      840

gacctggagg agcccaacag cctgaccaag acctgtgact ttgaccatct ggcggccttc      900

gatggggcca gcgaggaggc acccctgctg gggaattggt gtggacacca cctgccacca      960

cccgtgacct caagccacaa ccagcttctg cttctgctgc acacagaccg cagcaccacc     1020

cgcaggggct tctctgtggc ctacatcgga ggtcagctgg gctgtgggag tgggtccact     1080

gagggcgaag gggaggcttt gcagcctcag tctttgcagt ctccttcctc catcccacca     1140

gtttgtcctg ccccccccat gaatggtctt ctccagctcc ttctccattg gctacaccct     1200

tgcccactct cgggacccct aagactggac ggtacggctc ccgcttgttt ccactattgc     1260

agagcctcct tccccagctt c                                               1281


<210>  5597
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  5597
tggtgttctg aagaggaaat gggtggtaat aataaaatag tccaggatcc tatgttcctc       60

gccacagtgg agtttgcctt gaacactttc aacgtgcaga gcaaggagga gcatgcctac      120

aggctgttgc gcgtcctgag ttcatggagg gaggatagca tggacagaaa gtggcgaggt      180

aagatggtgt tctccatgaa tctgcaactg cgccaaaccg tatgtaggaa atttgaagat      240

gacattgaca actgcccttt tcaagaaagc ctggagctga acaacgtaag acagggcatc      300

agctttcctc aggtccacag ctgtggatgc tgcatggggt gtggtgtggg cacaggagca      360

gctgacaaag ccattccgag ggacaaaggg aag                                   393


<210>  5598
<211>  2184
<212>  DNA
<213>  Homo Sapiens

<400>  5598
attgtcctca cagggacaag cgagccccca gatgcgcaga cagtggcgcc tgcggaggac       60

gagactctgc aaaacgaggc ggacaaccag gagaacgttt tatctcagtt gctgggggac      120

tatgacaagg tcaaggctat gtctgagggc tcggactgtc agtgcaagtg tgtggtgaga      180

cccctgggcc gggatgcctg ccagaggatc aatgcggggg cctccaggaa ggaagacttc      240

tataccgtgg aaaccatcac ctcaggctcg tcgtgcaagt gtgcctgtgt agcaccccca      300

tcggccctca atccctgcga gggagacttc aggctccaga agctgcggga ggcagacagc      360

caggacttga agctctccac aatcatagac atgttggaag gagcgttcta tggcctggat      420

ctcctgaagc tacattcagt caccaccaaa ctggtggggc gagtggataa actggaggag      480

gaagtgtcta aaaacctcac caaggaaaac gaacaaatca aagaggacat ggaagaaatt      540

cgaaccgaga tgaataagcg aggcaaagaa aattgctctg aaaacatcct agatagcatg      600

ccagacatcc gctcagccct gcagagggat gcagcagcag cctacgccca cccagagtat      660

gaagagcggt ttctgcagga agaaaccgtg tcccagcaga tcaactccat cgaacttctg      720

cagacgcgac ccctggctct gcctgaggtg gtgaagtcac agcggcccct gcagaggcag      780

gtccacctga gaggccggcc ggcctcccag cccactgtca tccggggcat cacctactat      840

aaagccaagg tctctgaaga agagaatgac attgaagagc agcaagatga gtttttcagc      900

ggtgacaatg gagtggattt gctgattgaa gatcagctcc tgagacacaa cggcctgatg      960

accagtgtca cccggaggcc tgcagccacc cgtcagggac acagcactgc tgtgacaagc     1020

gacctgaacg ctcggaccgc accctggtcc tcagcactgc cacagccctc gacctcagat     1080

cccagcatcg ccaaccatgc ctcagtggga ccaacactcc aaacaacctc ggtgtctcca     1140

gatcccacaa gggagtcagt cctgcagcct tctcctcagg taccagccac cactgtggcc     1200

cacacagcca cccagcaacc agcagcccca gctcctccgg cagtgtctcc cagggaggca     1260

ttgatggaag ctatgcacac agtcccagtg cctcccacca cagtcagaac agactcgctg     1320

gggaaagatg ctcctgctgg gtggggaaca acccctgcca gccccacgct gagccccgaa     1380

gaagaagatg acatccggaa tgtcatagga aggtgcaagg acactctctc cacaatcacg     1440

gggccgacca cccagaacac atatgggcgg aatgaagggg cctggatgaa ggaccccctg     1500

gccaaggatg agcggattta cgtaaccaac tattactacg gcaacaccct ggtagagttc     1560

cggaacctgg agaacttcaa acaaggtcgc tggagcaatt cctacaagct cccgtacagc     1620

tggatcggca caggccacgt ggtatacaat ggcgccttct actacaatcg cgccttcacc     1680

cgcaacatca tcaagtacga cctgaagcag cgctacgtgg ctgcctgggc catgctgcat     1740

gacgtggcct acgaggaggc caccccctgg cgatggcagg gccactcaga cgtggacttt     1800

gctgtggacg agaatggcct atggctcatc tacccggccc tggacgatga gggcttcagc     1860

caggaggtca ttgtcctgag caagctcaat gccgcggacc tgagcacaca gaaggagacc     1920

acatggcgca cggggctccg gaggaatttc tacggcaact gcttcgtcat ctgtggggtg     1980

ctgtatgccg tggatagcta caaccagcgg aatgccaaca tctcctacgc tttcgacacc     2040

cacaccaaca cacagatcgt ccccaggctg ctgttcgaga atgagtattc ctatacgacc     2100

cagatagact acaaccccaa ggaccgcctg ctctatgcct gggacaatgg ccaccaggtc     2160

acttaccatg tcatctttgc ctac                                            2184


<210>  5599
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  5599
ctggatgtta gtacgacaat atacaaccgg tgcaagcatg ctgctgcaaa ttcaagccct       60

cctgagaata gcaacattac aggattgtac gcaactgcta accctgttcc aagccagcat      120

ccttgtttca agccatggag ttacattcct gatgga                                156


<210>  5600
<211>  522
<212>  DNA
<213>  Homo Sapiens

<400>  5600
ggctttggac gcacaggact ggtactggca gcagcggtgg agtctgaaag atcagcagaa       60

cagaaagcta ttatcagagt gatccccttg aaaatggacc ccacaggaaa actgaatctc      120

actttggaag gtgtgtttgc tggtgttgct gaaataactc cagcagaagg aaaattaatg      180

cagtcccacc cgctgtacct gtgcaatgcc agtgatgacg acaatctgga gcctggattc      240

atcagcatcg tcaagctgga gagtcctcga cgggcccccc gcccctgcct gtcactggct      300

agcaaggctc ggatggcggg tgagcgagga gccagtgctg tcctctttga catcactgag      360

gatcgagctg ctgctgagca gctgcagcag ccgctggggc tgacctggcc agtggtgttg      420

atctggggta atgacgctga gaagctgatg gagtttgtgt acaagaacca aaaggcccat      480

gtgaggattg agctgaagga gcccccggcc tggccagatt at                         522


<210>  5601
<211>  264
<212>  DNA
<213>  Homo Sapiens

<400>  5601
gggttccgcg ccacgcagcg ctacgacgac tgcttcagca cgaacatcct gaccctcatc       60

aacgggttcg acctgcctga aggcaacgtg acccaggaga actttgtgga catgcagcag      120

cggtgcaacg cctccgaccc cgcggcctac gcgcagctgg tgttccagac ctgcgacatc      180

aacgccttcc tctcagaggc cgtggagggc acaggcctgg ccttcatcgt cttcaccgag      240

gccatcacca agatgccgtt gtcc                                             264


<210>  5602
<211>  1365
<212>  DNA
<213>  Homo Sapiens

<400>  5602
ggccccctgc agagcggaga ggaaagcact gggacaaata ttggggaggc ccttggacat       60

ggcctgggag acgccctgag cgaaggggtg ggaaaggcca ttggcaaaga ggccggaggg      120

gcagctggct ctaaagtcag tgaggccctt ggccaaggga ccagagaagc agttggcact      180

ggagtcaggc aggttccagg ctttggcgca gcagatgctt tgggcaacag ggtcggggaa      240

gcagcccatg ctctgggaaa cactgggcac gagattggca gacaggcaga agatgtcatt      300

cgacacggag cagatgctgt ccgcggctcc tggcaggggg tgcctggcca caatggtgct      360

tgggaaactt ctggaggcca tggcatcttt ggctctcaag gtggccttgg aggccagggc      420

cagggcaatc ctggaggtct ggggactccg tgggtccacg gataccccgg aaactcagca      480

ggcagctttg gaatgaatcc tcagggagct ccctggggtc aaggaggcaa tggagggcca      540

ccaaactttg ggaccaacac tcagggagct gtggcccagc ctggctatgg ttcagtgaga      600

gccagcaacc agaatgaagg gtgcacgaat cccccaccat ctggctcagg tggaggctcc      660

agcaactctg ggggaggcag cggctcacag tcgggcagca gtggcagtgg cagcaatggt      720

gacaacaaca atggcagcag cagtggtggc agcagcagtg gcagcagcag tggcggcagc      780

agtggcggca gcagtggtgg cagcagtggc aacagtggtg gcagcagagg tgacagcggc      840

agtgagtcct cctggggatc cagcaccggc tcctcctccg gcaaccacgg tgggagcggc      900

ggaggaaatg gacataaacc cgggtgtgaa aagccaggga atgaagcccg cgggagcggg      960

gaatctggga ttcagaactc tgagacgtct cctgggatgt ttaactttga cactttctgg     1020

aagaatttta aatccaagct gggtttcatc aactgggatg ccataaacaa gaaccaggtc     1080

ccgcccccca gcacccgagc cctcctctac ttcagccgac tctgggagga tttcaaacag     1140

aacactcctt tcctcaactg gaaagcaatt attgagggtg cggacgcgtc atcactgcag     1200

aaacgtgcag gcagagccga tcagaactac aattacaacc agcatgcgta tcccactgcc     1260

tatggtggga agtactcagt caagacccct gcaaaggggg gagtctcacc ttcttcctcg     1320

gcttcccggg tgcaacctgg cctgctgcag tgggtgaagt tttgg                     1365


<210>  5603
<211>  984
<212>  DNA
<213>  Homo Sapiens

<400>  5603
gtgcgcggcg cgccctgcga ggcggtgcgc atccctatgt gccggcacat gccctggaac       60

atcacgcgga tgcccaacca cctgcaccac agcacgcagg agaacgccat cctggccatc      120

gagcagtacg aggagctggt ggacgtgaac tgcagcgccg tgctgcgctt cttcctctgt      180

gccatgtacg cgcccatttg caccctggag ttcctgcacg accctatcaa gccgtgcaag      240

tcggtgtgcc aacgcgcgcg cgacgactgc gagcccctca tgaagatgta caaccacagc      300

tggcccgaaa gcctggcctg cgacgagctg cctgtctatg accgtggcgt gtgcatctcg      360

cctgaagcca tcgtcacgga cctcccggag gatgttaagt ggatagacat cacaccagac      420

atgatggtac aggaaaggcc tcttgatgtt gactgtaaac gcctaagccc cgatcggtgc      480

aagtgtaaaa aggtgaagcc aactttggca acgtatctca gcaaaaacta cagctatgtt      540

attcatgcca aaataaaagc tgtgcagagg agtggctgca atgaggtcac aacggtggtg      600

gatgtaaaag agatcttcaa gtcctcatca cccatccctc gaactcaagt cccgctcatt      660

acaaattctt cttgccagtg tccacacatc ctgccccatc aagatgttct catcatgtgt      720

tacgagtggc gttcaaggat gatgcttctt gaaaattgct tagttgaaaa atggagagat      780

cagcttagta aaagatccat acagtgggaa gagaggctgc aggaacagcg gagaacagtt      840

caggacaaga agaaaacagc cgggcgcacc agtcgtagta atccccccaa accaaaggga      900

aagcctcctg ctcccaaacc agccagtccc aagaagaaca ttaaaactag gagtgcccag      960

aagagaacaa acccgaaaag agtg                                             984


<210>  5604
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  5604
tgcggggtcc ccgccatcca ccctgtgctc agcggcctgt ccaggatcgt gaatggggag       60

gacgccgtcc ccggctcctg gccctggcag gtgtccctgc aggacaaaac cggcttccac      120

ttctgcgggg gctccctcat cagcgaggac tgggtggtca ccgctgccca ctgcggggtc      180

aggacctccg acgtggtcgt ggctggggag tttgaccagg gctctgacga ggagaacatc      240

caggtcctga agatcgccaa ggtcttcaag aaccccaagt tcagcattct gaccgtgaac      300

aatgacatca ccctgctgaa gctggccaca cctgcccgct tctcccagac agtgtccgcc      360

gtgtgcctgc ccagcgccga cgacgacttc cccgcgggga cactgtgtgc caccacaggc      420

tggggcaaga ccaagtacaa cgccaacaag acccctgaca agctgcagca ggcagccctg      480

cccctcctgt ccaatgccga atgcaagaag tcctggggca ggaggatcac cgacgtgatg      540

atctgtgccg gggccagtgg cgtctcctcc tgcatgggtg actctggagg ccccctggtc      600

tgccagaagg acggagcctg gaccctggtg ggcattgtgt cctggggcag ccgcacctgc      660

tctaccacca cgcccgctgt gtacgcccgt gtcaccaagc tcataccctg ggtgcagaag      720

atcctggccg ccaac                                                       735


<210>  5605
<211>  1635
<212>  DNA
<213>  Homo Sapiens

<400>  5605
ctccccgtga agaagccgcg gctccgcgga ccacggcctg ggagcctcac gaggctcgca       60

gaggtctcag cctccccaga tcctaggcct ctgaaggaag aggaggaggc accactgctc      120

cccagaaccc acctgcaggc agagccacac caacatggat gctggactgt cactgagcca      180

gcagccatga ccccaggcaa caccacccct cccaggaccc cagaggttac tccgttgcgg      240

ctggagctgc agaagctgcc gggattggcc aacacaacct tgagtacccc taaccctgat      300

acccaggctt cagcctcccc agatcctagg cctctgaggg aagaggagga ggcacgactg      360

ctccccagaa cccacctgca ggcagagcta caccaacatg gatgttggac tgtcactgag      420

ccagcagccc tgaccccagg gaatgccacg cctcccagga cccaggaggt tactcccttg      480

ctgctggagc tgcagaagct gccagaattg gtccacgcaa ccttgagtac ccctaaccct      540

gataaccagg tgaccatcaa ggtggtggag gacccccagg ccgaggtgtc gatagacctg      600

ttggctgagc ccagcaatcc cccgccccag gataccctta gctggctgcc cgccctctgg      660

tccttcctct ggggagacta caaaggagag gaaaaagaca gggccccagg ggagaagggg      720

gaggaaaagg aggaagacga ggactatcct tcagaggata tcgagggtga ggatcaagag      780

gacaaagagg aagatgagga agagcaggcg ctctggttca atggaactac agacaactgg      840

gaccagggct ggctggcccc cggggattgg gtcttcaagg attctgtcag ctacgactat      900

gagcctcaga aggagtggag tccctggtct ccctgcagtg ggaactgcag cactggcaag      960

cagcagagga ctcggccctg tggctatggc tgcactgcca ccgagacccg tacctgtgac     1020

ctgccctcct gtcctggcac tgaggacaag gacaccttgg gcctccccag tgaggagtgg     1080

aagctcctgg cccgcaatgc tacggacatg catgatcaag atgtggacag ctgtgagaag     1140

tggctgaact gcaagagcga cttcctaatc aagtatctga gccagatgct gcgggacctg     1200

cccagctgcc cgtgtgccta cccactggag gccatggaca gccctgtgag cctacaggac     1260

gagcaccagg gccgcagctt ccggtggagg gatgccagtg gccctcgcga gcgcctggac     1320

atctaccagc ccacggcgcg cttctgcctg cgttccatgc tgtctgggga gagcagcaca     1380

ctggccgccc agcactgctg ctatgacgag gacagccggc tgctgacccg tggcaagggc     1440

gccggcatgc ccaacctcat cagcaccgac ttctcaccta agctgcactt caagttcgac     1500

acgacgccct ggatcctgtg caagggggac tggagccgcc tccacgctgt gctccctccc     1560

aacaacggcc gagcctgcac cgacaacccc ctggaggagg agtacctagc acagttgcag     1620

gaggccaagg agtac                                                      1635


<210>  5606
<211>  1224
<212>  DNA
<213>  Homo Sapiens

<400>  5606
gcgcccctgg cctccagctg cgcaggagcc tgtggtacca gcttcccaga tggcctcacc       60

cctgagggaa cccaggcctc cggggacaag gacattcctg caattaacca agggctcatc      120

ctggaagaaa ccccagagag cagcttcctc atcgaggggg acatcatccg gccgagtccc      180

ttccgactgc tgtcagcaac cagcaacaaa tggcccatgg gtggtagtgg tgtcgtggag      240

gtccccttcc tgctctccag caagtacgat gagcccagcc gccaggtcat cctggaggct      300

cttgcggagt ttgaacgttc cacgtgcatc aggtttgtca cctatcagga ccagagagac      360

ttcatttcca tcatccccat gtatgggtgc ttctcgagtg tggggcgcag tggagggatg      420

caggtggtct ccctggcgcc cacgtgtctc cagaagggcc ggggcattgt ccttcatgag      480

ctcatgcatg tgctgggctt ctggcacgag cacacgcggg ccgaccggga ccgctatatc      540

cgtgtcaact ggaacgagat cctgccaggc tttgaaatca acttcatcaa gtctcggagc      600

agcaacatgc tgacgcccta tgactactcc tctgtgatgc actatgggag gcttgccttc      660

agccggcgtg ggctgcccac catcacacca ctttgggccc ccagtgtcca catcggccag      720

cgatggaacc tgagtgcctc ggacatcacc cgggtcctcc aactctacgg ctgcagccca      780

agtggcccca ggccccgtgg gagagggtcc catgcccaca gcactggtag gagccccgct      840

ccggcctccc tatctctgca gcggcttttg gaggcactgt cggcggaatc caggagcccc      900

gaccccagtg gttccagtgc gggaggccag cccgttcctg cagggcctgg ggagagccca      960

catgggtggg agtcccctgc cctgaaaaag ctcagtgcag aggcctcggc aaggcagcct     1020

cagaccctgg cttcctcccc aagatcaagg cctggagcag gtgcccccgg tgttgctcag     1080

gagcagtcct ggctggccgg agtgtccacc aagcccacag tcccatcttc agaagcagga     1140

atccagccag tccctgtcca gggaagccca gctctgccag ggggctgtgt acctagaaat     1200

catttcaagg ggatgtccga agat                                            1224


<210>  5607
<211>  228
<212>  DNA
<213>  Homo Sapiens

<400>  5607
tctgtttcag gccctagaca ctggtggcca ccacgtggaa ttattaaggt gaaatgtcca       60

tatgagaaag taaacttgag ctggtacaat ggaacggtca acccctgccc tggcttatat      120

caacccatct gcggcaccaa ttttataacc tatgataatc cctgcattct gtgtgttgag      180

agcttgaaat ctcatggaag aatcaggttt taccatgatg gaaaatgt                   228


<210>  5608
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5608
acaccctttc cttctctggc cccaccaatc atgctgctgg tggatggaaa gcagcagatg       60

gtggtggtct gcctggtcct tgatgttgca ccccctggcc ttgacagccc catctggttc      120

tcagccggca atggcagtgc actggatgcc ttcacctatg gcccttcccc agcaacggat      180

ggcacctgga ccaacttggc ccatctctcc ctgccttctg aggagctggc atcctgggag      240

cctttggtct gccacactgg gcctggggct gagggtcaca gcaggagtac acagcccatg      300

catctgtcag gagaggcttc tacagccagg acctgccccc aggagcctct cagggggaca      360

ccgggtggg                                                              369


<210>  5609
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  5609
actaggggct cgtctacagg agctcacatt agcccccagt ttccagcttc aggtgtgaac       60

cagacccccg tggtagactg ccgcaaggtg tgtggcctga atgtctctga ccgctgtgac      120

ttcatccgga ccaaccctga ctgccacagt gatggggggt acctggacta cctggaaggc      180

atcttctgcc acttccctcc cagcctc                                          207


<210>  5610
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  5610
aggaagagac ggttcccctt cattggtgag gatgacaatg acgatggtca cccacttcat       60

ccatctctga atattcctta tggcatacgg aatttaccac ctcctcttta ttatcgccca      120

gtgaatacag tccccagtta ccctgggaat acttacactg acacagggtt accttcgtat      180

ccctggattc taacttctcc tggattcccc tatgtctatc acatccgtgg ttttccctta      240

gctactcagt tgaatgttcc tcctctccct cctaggggtt tcccgtttgt ccctccttca      300

aggttttttt cagcagctgc agcacccgct gccccaccta ttgcagctga gcctgctgca      360

gctgcacctc ttacagccac acctgtagca gctgagcctg ctgcaggggc ccctgttgca      420

gctgagcctg ctgcagaggc acctgttgga gctgagcctg ctgcagaggc acctgttgca      480

gctgagcctg ctgcagaggc acctgttgga gtggagccag ctgcagagga accttcacca      540

gctgagcctg ctacagccaa gcctgctgcc ccagaacctc acccttctcc ctctcttgaa      600

caggcaaatc ag                                                          612


<210>  5611
<211>  1911
<212>  DNA
<213>  Homo Sapiens

<400>  5611
tacagcgtct ccctacgcaa ggcggagcga cttcgcgcgg agctgctgga cctgaaagct       60

ggcggcttct ccatccgcaa tcagaaggga gagcaggtct tccgcctggc cttccgctcc      120

ggcgcgctgg accttgactc ctgcagccgc gatggcgccc tgctgggctg ctcgctcacg      180

gccgacgggc tgccgctgca cttcttcatc cagactgtgc ggcccaagga cacggtcatg      240

tgctaccgcg tgcgctggga ggaggcagcg ccgggccggg ccgtggagca cgccatgttc      300

ttgggcgacg cggcggccca ctggtatggt ggcgccgaga tgaggacgca acactggccc      360

atccgcctgg atggccagca ggagccccag ccgttcgtca ccagcgatgt ctactcctcc      420

gacgccgcgt ttgggggcat cctcgagcgc tactggctat cttcgcgcgc ggccgccatc      480

aaagtcaatg actcagtgcc cttccacctg ggctggaaca gcacggagcg ctcgctgcgg      540

cttcaggcgc gctaccacga cacgccctac aagccacccg ccggccgcgc cgcagcgcca      600

gagctgagct accgagtgtg cgtgggctca gacgtcacct ccatccacaa gtacatggtg      660

cgtcgctact tcaacaagcc gtcaagggtg ccagcacccg aggccttccg agaccccatt      720

tggtccacat gggcgctgta cgggcgcgcc gtggaccagg acaaggtgct gcgttttgcc      780

caacagatcc gcctgcacca cttcaacagc agccacctgg aaatcgacga catgtacaca      840

cctgcttatg gcgacttcga cttcgatgag gtcaaattcc ccaacgccag cgacatgttc      900

cgccgcctgc gcgacgccgg cttccgcgtc acgctctggg tgcacccttt tgtcaactac      960

aactcgtcgc gcttcggcga gggcgtggag cgcgagctgt tcgtgcgcga acccacgggc     1020

cggttacctg cgctggtgcg ctggtggaac ggcatcggcg cggtgctaga cttcacgcac     1080

ccaaaggccc gcgactggtt ccagggacac ctgcggcggc tgcgctctcg ctactccgtg     1140

gcttccttca agttcgacgc gggcgaggtc agctacctgc cgcgggactt cagcacctac     1200

cggccgctgc cggaccccag cgtctggagc cggcgctaca ctgagatggc gctgcccttc     1260

ttctcgctgg cggaggtgcg cgtaggctac cagtcacaga acatctcctg cttcttccgc     1320

ctggtggatc gcgactctgt gtggggctac gacctggggt tgcgctcact catccccgcg     1380

gtgctcaccg tcagcatgct gggctaccca ttcatcctac ccgatatggt gggcggcaac     1440

gccgtgcccc agcggacagc cggcggcgat gtgcccgagc gcgagctcta cattcgctgg     1500

ctggaagtgg ccgcctttat gccggccatg cagttctcta tcccgccctg gcgctacgac     1560

gcggaagtgg tggccatcgc gcagaagttc gccgccctgc gggcctcgct tgtggcaccg     1620

ctgttgcttg agctggcggg cgaggtcacc gacacgggtg accctatcgt gcgccccctt     1680

tggtggattg cgcccggcga cgagacagct caccgtatcg actcgcagtt ccttattggg     1740

gacacgctgc ttgtggcccc ggtgctggag ccaggcaagc aggagcgcga cgtctatttg     1800

cccgccggca agtggcgcag ctacaagggt gagcttttcg acaagacgcc ggtgctgctc     1860

accgattacc cggtcgacct ggatgagatc gcctacttta cctgggcgtc c              1911


<210>  5612
<211>  603
<212>  DNA
<213>  Homo Sapiens

<400>  5612
tctcccagta ttcgccagaa gaaactaatg cacaagctgc aggaggaaaa ggcttttcgc       60

gaagagatga aaatttttcg tgaaaaaata gaggacttca gggaagagat gtggactttc      120

cgaggcaaga tccatgcttt ccggggccag atcctgggtt tttgggaaga ggagagacct      180

ttctgggaag aggagaaaac cttctggaaa gaggaaaaat ccttctggga aatggaaaag      240

tctttcaggg aggaagagaa aactttctgg aaaaagtacc gcactttctg gaaggaggat      300

aaggccttct ggaaagagga caatgcctta tgggaaagag accggaacct tcttcaggag      360

gacaaggccc tgtgggagga agaaaaggcc ctgtgggtag aggaaagagc cctccttgag      420

ggggagaaag ccctgtggga agataaaacg tccctctggg aggaagagaa tgccctctgg      480

gaggaagaga gggccttctg gatggagaac aatggccacg ttgccggaga gcagatgctc      540

gaagatgggc cccacaacgc caacagaggg cagcgcttgc tggccttctc ccgaggcagg      600

gcg                                                                    603


<210>  5613
<211>  1776
<212>  DNA
<213>  Homo Sapiens

<400>  5613
aaagtttact tgggactatt ctctggcagc tccccgaatc ctttctccga agatgtcaaa       60

cggcccccag cgcccctggt aactgacaag gaggccagga agaaggttct caaacaagct      120

ttttcagcca accaagtgcc ggagaagctg gatgtggtgg taattggcag tggctttggg      180

ggcctggctg cagctgcaat tctagctaaa gctggcaagc gagtcctggt gctggaacaa      240

cataccaagg cagggggctg ctgtcatacc tttggaaaga atggccctga atttgacaca      300

ggaatccatt acattgggcg tatggaagag ggcagcattg gccgttttat cttggaccag      360

atcactgaag ggcagctgga ctgggctccc ctgtcctctc cttttgacat catggtactg      420

gaagggccca atggccgaaa ggagtacccc atgtacagtg gagagaaagc ctacattcag      480

ggcctcaagg agaagtttcc acaggaggaa gctatcattg acaagtatat aaagctggtt      540

aaggtggtat ccagtggagc ccctcatgcc atcctgttga aattcctccc attgcccgtg      600

gttcagctcc tcgacaggtg tgggctgctg actcgtttct ctccattcct tcaagcatcc      660

acccagagcc tggctgaggt cctgcagcag ctgggggcct cctctgagct ccaggcagta      720

ctcagctaca tcttccccac ttacggtgtc acccccaacc acagtgcctt ttccatgcac      780

gccctgctgg tcaaccacta catgaaagga ggcttttatc cccgaggggg ttccagtgaa      840

attgccttcc acaccatccc tgtgattcag cgggctgggg gcgctgtcct cacaaaggcc      900

actgtgcaga gtgtgttgct ggactcagct gggaaagcct gtggtgtcag tgtgaagaag      960

gggcatgagc tggtgaacat ctattgcccc atcgtggtct ccaacgcagg actgttcaac     1020

acctatgaac acctactgcc ggggaacgcc cgctgcctgc caggtgtgaa gcagcaactg     1080

gggacggtgc ggcccggctt aggcatgacc tctgttttca tctgcctgcg aggcaccagg     1140

gaagacctgc atctgccgtc caccaactac tatgtttact atgacacgga catggaccag     1200

gcgatggagc gctacgtctc catgcccagg gaagaggctg cggaacacat ccctcttctc     1260

ttcttcgctt tcccatcagc caaagatccg acctgggagg accgattccc aggccggtcc     1320

accatgatca tgctcatacc cactgcctac gagtggtttg aggagtggca ggcggagctg     1380

aagggaaagc ggggcagtga ctatgagacc ttcaaaaact cctttgtgga agcctctatg     1440

tcagtggtcc tgaaactgtt cccacagctg gaggggaagg tggagagtgt gactgcagga     1500

tccccactca ccaaccagtt ctatctggct gctccccgag gtgcctgcta cggggctgac     1560

catgacctgg gccgcctgca cccttgtgtg atggcctcct tgagggccca gagccccatc     1620

cccaacctct atctgacagg ccaggatatc ttcacctgtg gactggtcgg ggccctgcaa     1680

ggtgccctgc tgtgcagcag cgccatcctg aagcggaact tgtactcaga ccttaagaat     1740

cttgattcta ggatccgggc acagaagaaa aagaat                               1776


<210>  5614
<211>  1677
<212>  DNA
<213>  Homo Sapiens

<400>  5614
cagccctctt cctccccatc aggggcagtg cccacgtctt tggagctgca gcgagggacg       60

gatggcggaa ccctccagtc cccttcagag gcgactgcaa ctcgcccggc cgtgcctgga      120

ctccctacag tggtccctac tctcgtgact ccctcggccc ctgggaatag gactgtggac      180

ctcttcccag tcttaccgat ctgtgtctgt gacttgactc ctggagcctg cgatataaat      240

tgctgctgcg acagggactg ctatcttctc catccgagga cagttttctc cttctgcctt      300

ccaggcagcg taaggtcttc aagctgggtt tgtgtagaca actctgttat cttcaggagt      360

aattccccgt ttccttcaag agttttcatg gattctaatg gaatcaggca gttttgtgtc      420

catgtgaaca actcaaactt aaactatttc cagaagcttc aaaaggtcaa tgcaaccaac      480

ttccaggccc tggctgcaga gtttggaggc gaatcattca cttcaacatt ccaaactcaa      540

tcaccaccat ctttttacag ggctggggac cccattctta cttacttccc caagtggtct      600

gtaataagct tgctgagaca acctgcagga gttggagctg ggggactctg tgctgaaagc      660

aatcctgcag gtttcctaga gagtaaaagt acaacttgca ctcgtttttt caagaacctg      720

gctagtagct gtaccttgga ttcagccctc aatgctgcct cttactataa cttcacagtc      780

ttaaaggttc caagaagcat gactgatcca cagaatatgg agttccaggt tcctgtaata      840

cttacctcac aggctaatgc tcctctgttg gctggaaaca cttgtcagaa tgtagtttct      900

caggtcacct atgagataga gaccaatggg acttttggaa tccagaaagt ttctgtcagt      960

ttgggacaaa ccaacctgac tgttgagcca ggcgcttcct tacagcaaca cttcatcctt     1020

cgcttcaggg cttttcaaca gagcacagct gcttctctca ccagtcctag aagtgggaat     1080

cctggctata tagttgggaa gccactcttg gctctgactg atgatataag ttactcaatg     1140

accctcttac agagccaggg taatggaagt tgctctgtta aaagacatga agtgcagttt     1200

ggagtgaatg caatatctgg atgcaagctc aggttgaaga aggcagactg cagccacttg     1260

cagcaggaga tttatcagac tcttcatgga aggcccagac cagagtatgt tgccatcttt     1320

ggtaatgctg acccagccca gaaaggaggg tggaccagga tcctcaacag gcactgcagc     1380

atttcagcta taaactgtac ttcctgctgt ctcataccag tttccctgga gatccaggta     1440

ttgtgggcat atgtaggtct cctgtccaac ccgcaagctc atgtatcagg agttcgattc     1500

ctataccagt gccagtctat acaggattct cagcaagtta cagaagtatc tttgacaact     1560

cttgtgaact ttgtggacat tacccagaag ccacagcctc caaggggcca acccaaaatg     1620

gactggaaat ggccattcga cttctttccc ttcaaagtgg cattcagcag aggagta        1677


<210>  5615
<211>  1383
<212>  DNA
<213>  Homo Sapiens

<400>  5615
gccaaaatcc tgacaatatc tacactgggt ggaagccatt acctactgtt ggaccgggtg       60

tctcagattc ttcaagagca tggtcataat gtgactatgc ttcatcagag tggaaagttt      120

ttgatcccag atattaaaga ggaggaaaaa tcataccaag ttatcaggtg gttttcacct      180

gaagatcatc aaaaaagaat taagaagcat tttgatagct acatagaaac agcattggat      240

ggcagaaaag aatctgaagc ccttgtaaag ctaatggaaa tatttgggac tcaatgtagt      300

tatttgctaa gcagaaagga tataatggat tccttaaaga atgagaacta tgatctggta      360

tttgttgaag catttgattt ctgttctttc ctgattgctg agaagcttgt gaaaccattt      420

gtggccattc ttcccaccac attcggctct ttggattttg ggctaccaag ccccttgtct      480

tatgttccag tattcccttc cttgctgact gatcacatgg acttctgggg ccgagtgaag      540

aattttctga tgttctttag tttctccagg agccaatggg acatgcagtc tacatttgac      600

aacaccatca aggagcattt cccagaaggc tctaggccag ttttgtctca tcttctactg      660

aaagcagagt tgtggtttgt taactctgat tttgcctttg attttgcccg gcccctgctt      720

cccaacactg tttatattgg aggcttgatg gaaaaaccta ttaaaccagt accacaagac      780

ttggacaact tcattgccaa ctttggggat gcagggtttg tccttgtggc ctttggctcc      840

atgttgaaca cccatcagtc ccaggaagtc ctcaagaaga tgcacaatgc ctttgcccac      900

ctccctcaag gagtgatatg gacatgtcag agttctcatt ggcccagaga tgttcatttg      960

gccacaaatg tgaaaattgt ggactggctt cctcagagtg acctcctggc tcaccccagc     1020

atccgtcttt ttgtcactca tggtgggcag aacagcgtaa tggaggccat ccgtcatggt     1080

gtgcccatgg tgggattacc agtcaatgga gaccagcatg gaaacatggt ccgagtagta     1140

gccaaaaatt atggtgtctc tatccggttg aatcaggtca cagccgacac actgacactt     1200

acaatgaaac aagtcataga agacaagagg tacaagtcgg cagtggtggc agccagtgtc     1260

atcctgcact ctcagcccct gagccccgca cagcggctgg tgggctggat cgaccacatc     1320

ctccagactg ggggagcgac gcacctcaag ccctatgcct tccagcagcc ttggcatgag     1380

cag                                                                   1383


<210>  5616
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  5616
atgggggcac aggtgaggct gccgcccgga gagccctgcc gagaaggata tgtgctgtct       60

ctggtctgtc caaactcctc ccaggcttgg tgtgagatca caaatgtgtc acagctgctg      120

gcttctcctg tgctctacac ggacctgaat tacagcataa acaacttgag catttcagca      180

aatgtagaaa acaaatacag t                                                201


<210>  5617
<211>  1104
<212>  DNA
<213>  Homo Sapiens

<400>  5617
ggtgactgcc aacagccagc ccaatgtcga atccagaaat gcaccacgga cttcgtgtcc       60

ctgacttctc acctgaactc tgccgttgac ggctttgact ctgagttttg caaggccttg      120

cgtgcctatg ctggctgcac ccagcgaact tcaaaagcct gccgtggcaa cctggtatac      180

cattctgccg tgttgggtat cagtgacctc atgagccaga ggaattgttc caaggatgga      240

cccacatcct ctaccaaccc cgaagtgacc catgatcctt gcaactatca cagccacgct      300

ggagccaggg aacacaggag aggggaccag aaccctccca gttacctttt ttgtggcttg      360

tttggagatc ctcacctcag aactttcaag gataacttcc aaacatgcaa agtagaaggg      420

gcctggccac tcatagataa taattatctt tcagttcaag tgacaaacgt acctgtggtc      480

cctggatcca gtgctactgc tacaaataag atcactatta tcttcaaagc ccaccatggg      540

tgtacagatc agaaagtcta ccaagctgtg acagatgacc tgccggccgc ctttgtggat      600

ggcaccacca gtggtgggga cagcgatgcc aagagcctgc gtatcgtgga aagggagagt      660

ggccactatg tggagatgca cgcccgctat atagggacca cagtgtttgt gcggcaggtg      720

ggtcgctacc tgacccttgc catccgtatg cctgaagacc tggccatgtc ctacgaggag      780

agccaggacc tgcagctgtg cgtgaacggc tgccccctga gtgaacgcat cgatgacggg      840

cagggccagg tgtctgccat cctgggacac agcctgcctc gcacctcctt ggtgcaggcc      900

tggcctggct acacactgga gactgccaac actcaatgcc atgagaagat gccagtgaag      960

gacatctatt tccagtcctg tgtcttcgac ctgctcacca ctggtgatgc caactttact     1020

gccgcagccc acagtgcctt ggaggatgtg gaggccctgc acccaaggaa ggaacgctgg     1080

cacattttcc ccagcagtgg caat                                            1104


<210>  5618
<211>  1149
<212>  DNA
<213>  Homo Sapiens

<400>  5618
ttttacactc ccatgccaga caacattgaa gaaagctgga aaataatggc cttggatgcc       60

atcgctaaaa cttgtacatt tacggctatg tgttttgaaa atatgcgtat tatgagatat      120

gaagagttta tatccatgat attcaggctg gattataccc aaccactttc agatgaatac      180

atcacagtga ctgatacaac atttgttgac attccagtac gattgtactt gccaaaaaga      240

aagtcagaaa cccgaaggcg agctgtgata tattttcatg gtggtggttt ttgttttgga      300

agttccaaac agagggcttt tgacttcctg aatagatgga cggcaaacac gcttgatgct      360

gttgttgtag gcgtggacta taggctggct cctcaacacc actttcctgc tcagtttgaa      420

gatggccttg ctgcagtcaa attttttctt ttggaaaaaa ttcttacaaa atatggagtg      480

gatcccaccc gaatctgcat ttcgggagac agttctgggg gcaatttagc aacagcggtc      540

actcaacagg tgcagaatga tgctgaaata aaacataaaa tcaagatgca ggtcttactt      600

taccctggct tacagataac agattcttat ttgccatctc accgagaaaa tgagcatggt      660

atagttttga ccagggatgt agccataaaa ctcgtgagct tatatttcac caaggatgaa      720

gcacttccct gggcaatgag aagaaaccaa cacatgcctc tggagtcaag acatctgttt      780

aagtttgtta actggagtat tcttcttcct gagaagtata gaaaagacta tgtatatact      840

gaaccaattc ttggaggact tagttattca ttgccaggac ttacagacag cagagcatta      900

cccttgttgg ccaatgattc tcagttacag aatttgccac taacctatat tcttacttgt      960

caacatgatc tcttaagaga tgatggactt atgtatgtta caagacttcg aaatgttgga     1020

gtccaagttg ttcatgaaca tattgaggat ggaattcatg gagctttatc attcatgact     1080

tcaccatttt atttacgtct aggtcttagg ataagagata tgtatgtaag ttggctggat     1140

aagaattta                                                             1149


<210>  5619
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  5619
atggcgccgg tgggcggggg cgggcgcccg gtcggcggac cggcccgcgg gcgcctcctc       60

ctggcggcgc cggtgctgct ggtgctgctg tgggcgctgg gggcccgggg ccagggcagc      120

ccccagcagg gcacgatcgt gggcatgagg ctggcgagct gcaacaagtc gtgtgggacg      180

aacccggatg gcatcatctt cgtgtccgag ggcagcaccg tgaacctgag gctgtacggc      240

tacagcctgg gcaacatctc cagcaacctg atctccttca ccgaggtgga cgatgccgag      300

accctccaca agtccaccag ctgcctcgag ctcaccaagg acctggtcgt ccagcagctg      360

gtcaacgtga gccgcaggaa cacgtccggc gtgctggtgg tgctcaccaa gttcctccgg      420

aggagcgaga gcatgaagct gtatgcactg tgcacccggg cccagcccga cgggccctgg      480

ctgaagtgga cggacaagga ctcactgctc ttcatggtgg aggagcctgg gagg            534


<210>  5620
<211>  915
<212>  DNA
<213>  Homo Sapiens

<400>  5620
tccccgcctg ctggtctgct gagcctgctc acctctggcc agggcgctct ggatcaagag       60

gctctgggcg gcctgttaaa tacgctggcg gaccgtgtgc actgcaccaa cgggccgtgt      120

ggaaagtgcc tgtctgtgga ggacgccctg ggcctgggcg agcctgaggg gtcagggctg      180

cccccgggcc cggtcctgga ggccaggtac gtcgcccgcc tcagtgccgc cgccgtcctg      240

tacctcagca accccgaggg cacctgtgag gacactcggg ctggcctctg ggcctctcat      300

gcagaccacc tcctggccct gctcgagagc cccaaggccc tgaccccggg cctgagctgg      360

ctgctgcaga ggatgcaggc ccgggctgcc ggccagaccc ccaagacggc ctgcgtagat      420

atccctcagc tgctggagga ggcggtgggg gcgggggctc cgggcagtgc tggcggcgtc      480

ctggctgccc tgctggacca tgtcaggagc gggtcttgct tccacgcctt gccgagccct      540

cagtacttcg tggactttgt gttccagcag cacagcagcg aggtccctat gacgctggcc      600

gagctgtcag ccttgatgca gcgcctgggg gtgggcaggg aggcccacag tgaccacagt      660

catcggcaca ggggagccag cagccgggac cctgtgcccc tcatcagctc cagcaacagc      720

tccagtgtgt gggacacggt atgcctgagt gccagggacg tgatggctgc atatggactg      780

tcggaacagg ctggggtgac cccggaggcc tgggcccaac tgagccctgc cctgctccaa      840

cagcagctga gtggagcctg cacctcccag tccaggcccc ccgtccagga ccagctcagc      900

cagtcagaga ggtat                                                       915


<210>  5621
<211>  969
<212>  DNA
<213>  Homo Sapiens

<400>  5621
gaactcagcc gctccgacct cagcctcatc caacagcagc agcagcagca gcagcagcaa       60

caacaacaac aacagcaaaa gcagctggag gaggctgagg aggagaggac agaggtgcct      120

ggggcaacct ccaccttgac ggttccagtg tctgtattta tgttgaaagt ccaggtgaat      180

gacatcatca gtcgtcagta cctgagccaa gcagttgtag aagtgtttgt aaactacacg      240

aagacaaatt ccacagtaac taaaagcaat ggagcagtgc tgataaaagt accctacaaa      300

ttaggactta gtttaactat tattgcttac aaagatggct acgtgttgac ccctctgcct      360

tggaaaacca gaagaatgcc aatatattca tcagttacac tttcactgtt cccgcaaagc      420

caagcaaata tatggctatt tgaagacact gttttaatta ctggaaaatt agctgatgcc      480

aagtctcaac caagtgttca gttttcaaaa gccttaatta aacttcctga caaccatcat      540

attagcaacg ttactggcta tcttacagtt ctacaacagt ttttgaaagt ggacaatttt      600

ctgcatacaa ctggaattac tctcaataaa ccaggttttg aaaacattga attgactcct      660

cttgctgcaa tatgtgtgaa aatatattct ggaggaaaag aactaaaggt caatggctct      720

attcaagttt ctcttcctct tctacgtctg aatgatataa gtgcagggga tcgcatacct      780

gcttggacat ttgatatgaa cacaggtgct tggataaatc atggtcgggg aatggtcaag      840

gaacataaca atcatttaat ctggacatat gatgcaccac atttggggta ctggatagca      900

gctccacttc caggaactag aggttcaggt ataaatgaag attccaagga cataactgcc      960

taccacaca                                                              969


<210>  5622
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5622
aattatgagg aattagaaaa ctcaggagat acaactgtgg aatctgaaag accaaataaa       60

gtgactattc caagcacatt tgctgcagtg accatcaaag aaacattaaa tgcaaatata      120

aattctacca actttgctcc ggatgaaaat cagttagag                             159


<210>  5623
<211>  177
<212>  DNA
<213>  Homo Sapiens

<400>  5623
gaccaggtgg actggagtag actgtacaga gacactggtc tggtgaagat gtccaggaaa       60

ccacgagcct ccagcccatt ttccaacaac cacccatcaa caccaaagag gttcccaaga      120

caacccagaa gggaaaaggg acccgtcaag gaagttccag gaacaaaagg ctctccc         177


<210>  5624
<211>  453
<212>  DNA
<213>  Homo Sapiens

<400>  5624
ggctctgctc agggccctcc caagccaagg ctgcagacgc tgcgaatgac cctcccgagc       60

ccccacatgc cccggcccaa ccaaaccatc ctggtggacg tggcccggaa cgcggcgacc      120

atcacagtga ccccacctca gagcaaccac agctgggcgg tgctgttcga cgggcagagc      180

ggctgcatct gttaccgccc tgaggagcac caggtctgct tcctccgcct gatggaggac      240

agtgatcggg agaccctgcg gctgctggtg gatacctcca aggtccaaga ggcttgggtc      300

cccagccagg acacccacca cacccaggag ctgctggcag tgcaggggag cctcgaagtg      360

gaccccgccc aggcgggggc tttggtgcag cgcctgtgca tgaggacccc catctactgg      420

gcccggcgag cagaggggcc ccggagacag cgg                                   453


<210>  5625
<211>  1029
<212>  DNA
<213>  Homo Sapiens

<400>  5625
cggaaaggct tctgggacta cttcagccag accagcgggg acaaaggcag ggtggagcag       60

atccatcagc agaagatggc tcgcgagccc gcgaccctga aagacagcct tgagcaagac      120

ctcaacaata tgaacaagtt cctggaaaag ctgaggcctc tgagtgggag cgaggctcct      180

cggctcccac aggacccggt gggcatgcgg cggcagctgc aggaggagtt ggaggaggtg      240

aaggctcgcc tccagcccta catggcagag gcgcacgagc tggtgggctg gaatttggag      300

ggcttgcggc agcaactgaa gccctacacg atggatctga tggagcaggt ggccctgcgc      360

gtgcaggagc tgcaggagca gttgcgcgtg gtgggggaag acaccaaggc ccagttgctg      420

gggggcgtgg acgaggcttg ggctttgctg cagggactgc agagccgcgt ggtgcaccac      480

accggccgct tcaaagagct cttccaccca tacgccgaga gcctggtgag cggcatcggg      540

cgccacgtgc aggagctgca ccgcagtgtg gctccgcacg cccccgccag ccccgcgcgc      600

ctcagtcgct gcgtgcaggt gctctcccgg aagctcacgc tcaaggccaa ggccctgcac      660

gcacgcatcc agcagaacct ggaccagctg cgcgaagagc tcagcagagc ctttgcaggc      720

actgggactg aggaaggggc cggcccggac ccccagatgc tctccgagga ggtgcgccag      780

cgacttcagg ctttccgcca ggacacctac ctgcagatag ctgccttcac tcgcgccatc      840

gaccaggaga ctgaggaggt ccagcagcag ctggcgccac ctccaccagg ccacagtgcc      900

ttcgccccag agtttcaaca aacagacagt ggcaaggttc tgagcaagct gcaggcccgt      960

ctggatgacc tgtgggaaga catcactcac agccttcatg accagggcca cagccatctg     1020

ggggacccc                                                             1029


<210>  5626
<211>  1614
<212>  DNA
<213>  Homo Sapiens

<400>  5626
atggcggggc ccccggccct acccccgccg gagacggcgg cggccgccac cacggcggcc       60

gccgcctcgt cgtccgccgc ttccccgcac taccaagagt ggatcctgga caccatcgac      120

tcgctgcgct cgcgcaaggc gcggccggac ctggagcgca tctgccggat ggtgcggcgg      180

cggcacggcc cggagccgga gcgcacgcgc gccgagctcg agaaactgat ccagcagcgc      240

gccgtgctcc gggtcagcta caaggggagc atctcgtacc gcaacgcggc gcgcgtccag      300

ccgccccggc gcggagccac cccgccggcc ccgccgcgcg ccccccgcgg ggcccccgcc      360

gccgccgccg ccgccgcgcc gccgcccacg cccgccccgc cgccaccgcc cgcgcccgtc      420

gccgccgccg ccccggcccg ggcgccccgc gcggccgccg ccgccgccac agcgcccccc      480

tcgcctggcc ccgcgcagcc gggcccccgc gcgcagcggg ccgcgcccct ggccgcgccg      540

ccgcccgcgc cagccgctcc cccggcggtg gcgcccccgg ccggcccgcg ccgcgccccc      600

ccgcccgccg tcgccgcccg ggagccgccg ctgccgccgc cgccacagcc gccggcgccg      660

ccacagcagc agcagccgcc gccgccgcag ccacagccgc cgccggaggg gggcgcggtg      720

cgggccggcg gcgcggcgcg gcccgtgagc ctgcgggaag tcgtgcgcta cctcgggggc      780

agcggcggcg ccggcggtcg cctaacccgc ggccgcgtgc aggggctgct ggaggaggag      840

gcggcggctc gaggccgtct ggagcgcacc cgtctcggag cgcttgcgct gccccgcggg      900

gacaggcccg gacgggcgcc gccggccgcc agcgcccgcc cgtctcgcag caagagaggt      960

ggagaagagc gagtacttga gaaagaagag gaagaagatg atgatgaaga tgaagatgaa     1020

gaagatgatg tgtcagaggg ctctgaagtg cccgagagtg accgtcctgc aggtgcccag     1080

caccaccagc ttaacggcga gcggggacct cagagtgcca aggagagggt caaggagtgg     1140

accccctgcg gaccgcacca gggccaggat gaagggcggg ggccagcccc gggcagcggc     1200

acccgccagg tgttctccat ggcagccatg aacaaggaag ggggaacagc ttctgttgcc     1260

accgggccag actccccgtc ccccgtgcct ttgcccccag gcaaaccagc cctacctggg     1320

gccgacggga ccccctttgg ctgtccgccc gggcgcaaag agaagccatc tgatcccgtc     1380

gagtggaccg tgatggatgt cgtcgaatat tttactgagg ctggattccc ggagcaggcg     1440

acagctttcc aagagcagga aattgatggc aaatctttgc tgctcatgca gcgcacagat     1500

gtgctcaccg gcctgtccat ccgcctcggg ccagccctga aaatctacga gcaccacatc     1560

aaggtgcttc agcaaggcca ctttgaggat gatgaccccg atggcttctt aggc           1614


<210>  5627
<211>  756
<212>  DNA
<213>  Homo Sapiens

<400>  5627
cgtccacctc ccttcctctt ctgcccattg agcagtcaaa gaactgaaag tccttataag       60

cctgtgcacc tgggcctggg ccctacagat aaggtagctg ctattgctat ggcccgcatc      120

attgacctgg tgccctggga cgatggctcc acacatgtgt atgcctcccc ggccatcctg      180

cttcccatgg agcggcagcg caaccagctg gcgggcgtga agcagcagct ctaccaccca      240

gccctgccca ccctgcgcca catggacagg gacaccgtca aggcctgcct tcctgatgag      300

cactgccagt ccaccaccta ctgccgcaaa gatgaatttg acaacgccca ttttacactc      360

cttggggtcc ccaacaaacc cctgcagtgt ttggacatca ccgccacagg ccagaagctt      420

cgcaacaggt accacgaggg aaagctggcg cccatcgcgc caggcatcaa ccgagtggac      480

tggccctgct tcacgcgcgc catcgaggac tggtcccact tcgtgtcctc ggccggggag      540

ttcaagctgc cttgcctgag gaagcgagcg gagggtctca gcggctacgc ggtgcggtac      600

ttgaagcccg acgtgaccca gacctggcgg tactgcctca accagaaccc cagcctggac      660

cgctacggac agaagcccct gcctttcgac tccctgaaca ctttccgaag cttcggctcc      720

agctacagtc gtgtcaacta cctgaccccc tggcat                                756


<210>  5628
<211>  177
<212>  DNA
<213>  Homo Sapiens

<400>  5628
acaggaccgg gtatgacttt gcaactgaag ctgaaggagt cttttctgac aaattcctcc       60

tatgagtcca gcttcctgga attgcttgaa aagctctgcc tcctcctcca tctcccttca      120

gggaccagcg tcaccctcca ccatgcaaga tctcaacacc atgttgtctg caacaca         177


<210>  5629
<211>  993
<212>  DNA
<213>  Homo Sapiens

<400>  5629
tatccgagca taactgtgac acctgatgaa gagcaaaact tgaatcatta tatacaagtt       60

ttagagaacc tagtacgaag tgttccctct ggggagccag gtcgtgagaa aaaatctaac      120

tctccaaaac atgtttattc tatagcatca aagggatcaa aatttaagga gctagttaca      180

catggagacg cttcaactga gaatgatgtt ttaaccaatc ctatcagtga agaaactaca      240

actttcccta caggaggctt cacaccggaa ataggaaaga aaaaacacac ggaaagtacc      300

ccattctggt cgatcaaacc aaacaatgtt tccattgttt tgcatgcaga ggaaccttat      360

attgaaaatg aagagccaga gccagagccg gagccagctg caaaacaaac tgaggcacca      420

agaatgttgc cagttgttac tgaatcatct acaagtccat atgttacctc atacaagtca      480

cctgtcacca ctttagataa gagcactggc attgggatct ctacagaatc agaagatgtt      540

cctcagctct caggtgaaac tgcgatagaa aaacccgaag agtttggaaa gcacccagag      600

agttggaata atgatgacat tttgaaaaaa attttagata ttaattcaca agtgcaacag      660

gcacttctta gtgacaccag caacccagca tatagagaag atattgaagc ctctaaagat      720

cacctaaaac gaagccttgc tctagcagca gcagcagaac ataaattaaa aacaatgtat      780

aagtcccagt tattgccagt aggacgaaca agtaataaaa ttgatgacat cgaaactgtt      840

attaacatgc tgtgtaattc tagatctaaa ctctatgaat atttagatat taaatgtgtt      900

ccaccagaga tgagagaaaa agctgctaca gtattcaata cattaaaaaa tatgtgtaga      960

tcaaggagag tcacagcctt attaaaagtt tat                                   993


<210>  5630
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  5630
tctatgtgcc acaggtggag cagggctgtg ctcttccctg ccgcccaccg gccaaagagg       60

tcctcatcac tgccattgaa cccagtcctg cagacctccc tggaggaggt ggagctgctc      120

tacgagttcc tgctggccga acttgagatc agccctgacc tgcagatctc catcaaggac      180

gaggagctgg cctccttgcg gaaggcctca gacttccgca ccgtctgcaa caacgtcatc      240

cccaagagca tcccagacat ccgccggctc agcgccagcc tctccagcca ccctggcatc      300

ctcaagaaag aagactttga aaggacagtg ctgaccctgg cctacacagc ctaccgcaca      360

gccctgtccc acggccatca gaaggacatc tgggcgcagt ccctcgttag cctcttccag      420

gccctgaggc acgacttgat gcgctcctca cagccgggag tacctccc                   468


<210>  5631
<211>  1392
<212>  DNA
<213>  Homo Sapiens

<400>  5631
gggagggcct ctctccagca tggacaggcg gctgagaagg ggccacatcg cagccgcgac       60

accgccgagc catccttccc tgagataccc ctggatggta ccctggcccc tccagagtcc      120

cagggcaatg ggtccactct gcagcccaat gtggtgtaca ttaccctacg ctccaagcgc      180

agcaagccgg ccaatatccg tggcactgtg aagcccaagc gcaggaaaaa gcatgcagtg      240

gcatcggctg ccccagggca ggaggctttg gtcggaccat cccttcagcc gcaggaagcg      300

gcaagggaag ctgatgctgt agcacctggg tacgctcagg gagcaaacct ggttaagatt      360

ggagagcgac cctggaggtt ggtgcggggt ccgggagtgc gagccggggg cccagacttc      420

ctgcagccca gctccaggga gagcaacatt aggatctaca gcgagagcgc cccctcctgg      480

ctgagcaaag atgacatccg aagaatgcga ctcttggcgg acagcgcagt ggcagggctc      540

cggcctgtgt cctctaggag cggagcccgt ttgctggtgc tggagggggg cgcacctggc      600

gctgtgctcc gctgtggccc tagcccctgt gggcttctca agcagccctt ggacatgagt      660

gaggtgtttg ccttccacct agacaggatc ctggggctca acaggaccct gccgtctgtg      720

agcaggaaag cagagttcat ccaagatggc cgcccatgcc ccatcattct ttgggatgca      780

tctttatctt cagcaagtaa tgacacccat tcttctgtta agctcacctg gggaacttat      840

cagcagttgc tgaaacagaa atgctggcag aatggccgag tacccaagcc tgaatcaggt      900

tgtactgaaa tacatcatca tgagtggtcc aagatggcac tctttgattt tttgttacag      960

atttataatc gcttagatac aaattgctgt ggattcagac ctcgcaagga agatgcctgt     1020

gtacagaatg gattgaggcc aaaatgtgat gaccaaggtt ctgcggctct cgcacacatt     1080

atccagcgaa agcatgaccc aaggcatttg gtttttatag acaacaaggg tttctttgac     1140

aggagtgaag ataacttaaa cttcaaattg ttagaaggca tcaaagagtt tccagcttct     1200

gcagtttctg ttttgaagag ccagcactta cggcagaaac ttcttcagtc tctgtttctt     1260

gataaagtgt attgggaaag tcaaggaggt agacaaggaa ttgaaaagct tatcgatgta     1320

atagaacaca gagccaaaat tcttatcacc tatatcaatg cacacggggt caaagtatta     1380

cctatgaatg aa                                                         1392


<210>  5632
<211>  714
<212>  DNA
<213>  Homo Sapiens

<400>  5632
ctgcctacat cagctccttt gtctgtttct cttccgacaa acattgtacc accgaccacc       60

atctggacta gctctccaca aaacactgat gcagacactg cctccccatc caacggcact      120

cacaacaact cggtgctccc agttacagca tcagccccaa catctctgct tcctaagaac      180

atttccatag agtccagaga agaggagatc accagcccag gttcgaattg ggaaggcaca      240

aacacagacc cctcaccttc tgggttctcg tcaacaagcg gtggagtcca cttaacaacc      300

acgttgaagg aacacagctc gggcactcct gaagcaggcg tggcagctac actgtcgcag      360

tccgctgctg agcctcccac actcatctcc cctcaagctc cagcctcatc accctcatcc      420

ctatcaacct caccacctga ggtcttttct gcctccgtta ctaccaacca tagctccact      480

gtgaccagca cccaacccac tggagctcca actgcaccag agtccccgac agaggagtcc      540

agctctgacc acacacccac ttcacatgcc acagctgagc cagtacccca ggagaaaaca      600

cccccaacaa ctgtgtcagg caaagtgatg tgtgagctca tagacatgga gaccaccacc      660

acctttccca gggtgatcat gcaggaagta gaacatgcat taagttcagg cagc            714


<210>  5633
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5633
agcggcgagt actgccacgg ctggctggac gcgcagggcg tctggcgcat cggcttccag       60

tgtcccgagc gcttcgacgg cggcgacgcc accatctgct gcggcagctg cgcgttgcgc      120

tactgctgct ccagcgccga ggcgcgcctg gaccagggcg gctgcgacaa tgaccgccag      180

cagggcgctg gcgagcctgg ccgggcggac aaagacggcc ccgacggctc g               231


<210>  5634
<211>  789
<212>  DNA
<213>  Homo Sapiens

<400>  5634
gtggagcacg aggaggtggc gcagcgtgtg atcaaactgc accgcgggcg aggggtggct       60

gccatgcaga gccggcagtg ggtccgggac agctgcagga agctctcagg gcttctccgc      120

cagaagaatg cagttctgaa caaactgaaa actgcaattg gagcagtgga gaaagacgtg      180

ggcctgtcgg atgaagagaa actgtttcag gtgcacacgt ttgaaatttt ccagaaagag      240

ctgaatgaaa gtgaaaattc cgttttccaa gctgtctacg gactgcagag agccctgcag      300

ggggattaca aagatgtcgt gaacatgaag gagagcagcc ggcagcgcct ggaggccctg      360

agagaggctg caataaagga agaaacagaa tatatggaac ttctggcagc agaaaaacat      420

caagttgaag cccttaaaaa tatgcaacat caaaaccaaa gtttatccat gcttgacgag      480

attcttgaag atgtaagaaa ggcagcggat cgtctggagg aagagataga ggaacatgct      540

tttgacgaca ataaatcagt caagggggtc aattttgagg cagttctgag ggtggaggaa      600

gaagaggcca attctaagca aaatataaca aaacgagaag tggaggatga cttgggtctt      660

agcatgctga ttgactccca gaacaaccag tatattttga ccaagcccag agattcaacc      720

atcccacgtg cagatcacca ctttataaag gacattgtta ccataggaat gctgtccttg      780

ccttgtggc                                                              789


<210>  5635
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  5635
ggtaaaggag ctcgaggctt tgggagggga gccctgatcc gcctgaatat ctggccggcg       60

gtccaagggg cctgcaaaca gctggaggtc tgtgagcact gcgtggaggg agacagagcg      120

cgcaatctct ccagctgcat gtgggagcag tgccggccag aggagccagg acactgtgtg      180

gcccaatctg aggtggtcaa ggaaggttgc tccatctaca accgctcaga ggcatgtcca      240

gctgctcacc accaccccac ctatgaaccg aagacagtca caacagggag ccccccagtc      300

cctgaggccc acagccctgg atttgacggg gccagc                                336


<210>  5636
<211>  570
<212>  DNA
<213>  Homo Sapiens

<400>  5636
tccaaaatcc catccatcac tgacccacac tttatagaca actgcataga agcccacaac       60

gaatggcgtg gcaaagtcaa ccctcccgcg gccgacatga aatacatgat ttgggataaa      120

ggtttagcaa agatggctaa agcatgggca aaccagtgca aatttgaaca taatgactgt      180

ttggataaat catataaatg ctatgcagct tttgaatatg ttggagaaaa tatctggtta      240

ggtggaataa agtcattcac accaagacat gccattacgg cttggtataa tgaaacccaa      300

ttttatgatt ttgatagtct atcatgctcc agagtctgtg gccattatac acagttagtt      360

tgggccaatt cattttatgt cggttgtgca gttgcaatgt gtcctaacct tgggggagct      420

tcaactgcaa tatttgtatg caactacgga cctgcaggaa attttgcaaa tatgcctcct      480

tacgtaagag gagaatcttg ctctctctgc tcaaaagaag agaaatgtgt aaagaacctc      540

tgcaaaaatc catttctgaa gccaacgggg                                       570


<210>  5637
<211>  1557
<212>  DNA
<213>  Homo Sapiens

<400>  5637
cggaaggggt ccccagaaga ggcctccttc tactatggaa ccttccctct tggcttctcc       60

tggggcgtgg gcagttctgc ctaccagacg gagggcgcct gggaccagga cgggaaaggg      120

cctagcatct gggacgtctt cacacacagt gggaagggga aagtgcttgg gaatgagacg      180

gcagatgtag cctgtgacgg ctactacaag gtccaggagg acatcattct gctgagggaa      240

ctgcacgtca accactaccg attctccctg tcttggcccc ggctcctgcc cacaggcatc      300

cgagccgagc aggtgaacaa gaagggaatc gaattctaca gtgatcttat cgatgccctt      360

ctgagcagca acatcactcc catcgtgacc ttgcaccact gggatctgcc acagctgctc      420

caggtcaaat acggtgggtg gcagaatgtg agcatggcca actacttcag agactacgcc      480

aacctgtgct ttgaggcctt tggggaccgt gtgaagcact ggatcacgtt cagtgatcct      540

cgggcaatgg cagaaaaagg ctatgagacg ggccaccatg cgccgggcct gaagctccgc      600

ggcaccggcc tgtacaaggc agcacaccac atcattaagg cccacgccaa agcctggcat      660

tcttataaca ccacgtggcg cagcaagcag caaggtctgg tgggaatttc attgaactgt      720

gactgggggg aacctgtgga cattagtaac cccaaggacc tagaggctgc cgagagatac      780

ctacagttct gtctgggctg gtttgccaac cccatttatg ccggtgacta cccccaagtc      840

atgaaggact acattggaag aaagagtgca gagcaaggcc tggagatgtc gaggttaccg      900

gtgttctcac tccaggagaa gagctacatt aaaggcacat ccgatttctt gggattaggt      960

cattttacta ctcggtacat cacggaaagg aactacccct cccgccaggg gcccagctac     1020

cagaacgatc gtgacttgat agagctggtt gacccaaact ggccagatct ggggtctaaa     1080

tggctatatt ctgtgccatg gggatttagg aggctcctta actttgctca gactcaatac     1140

ggtgatcctc ccatatatgt gatggaaaat ggagcatctc aaaaattcca ctgtactcaa     1200

ttatgtgatg agtggagaat tcaatacctt aaaggataca taaatgaaat gctaaaagct     1260

ataaaagatg gtgctaatat aaaggggtat acttcctggt ctctgttgga taagtttgaa     1320

tgggagaaag gatactcaga tagatatgga ttctactatg ttgaatttaa cgacagaaat     1380

aagcctcgct atccaaaggc ttcagttcaa tattacaaga agattatcat tgccaatggg     1440

tttcccaatc caagagaggt ggaaagttgg tacctcaaag ctttggaaac ttgctctatc     1500

aacaatcaga tgcttgctgc agagcccttg ctaagtcaca tgcaaatggt tacggag        1557


<210>  5638
<211>  1404
<212>  DNA
<213>  Homo Sapiens

<400>  5638
gggaaagtcc tggtgtggcc ctgtgacatg agccattggc ttaatgtcaa ggtcattcta       60

gaagagctca tagtgagagg ccatgaggta acagtattga ctcactcaaa gccttcgtta      120

attgactaca ggaagccttc tgcattgaaa tttgaggtgg tccatatgcc acaggacaga      180

acagaagaaa atgaaatatt tgttgaccta gctctgaatg tcttgccagg cttatcaacc      240

tggcaatcag ttataaaatt aaatgatttt tttgttgaaa taagaggaac tttaaaaatg      300

atgtgtgaga gctttatcta caatcagaca cttatgaaga agctacagga aaccaactac      360

gatgtaatgc ttatagaccc tgtgattccc tgtggagacc tgatggctga gttgcttgca      420

gtcccttttg tgctcacact tagaatttct gtaggaggca atatggagcg aagctgtggg      480

aaacttccag ctccactttc ctatgtacct gtgcctatga caggactaac agacagaatg      540

acctttctgg aaagagtaaa aaattcaatg ctttcagttt tgttccactt ctggattcag      600

gattacgact atcatttttg ggaagagttt tatagtaagg cattaggaag gcccactaca      660

ttatgtgaga ctgtgggaaa agctgagata tggctaatac gaacatattg ggattttgaa      720

tttcctcaac cataccaacc taactttgag tttgttggag gattgcactg taaacctgcc      780

aaagctttgc ctaaggaaat ggaaaatttt gtccagagtt caggggaaga tggtattgtg      840

gtgttttctc tggggtcact gtttcaaaat gttacagaag aaaaggctaa tatcattgct      900

tcagcccttg cccagatccc acagaaggtg ttatggaggt acaaaggaaa aaaaccatcc      960

acattaggag ccaatactcg gctgtatgat tggatacccc agaatgatct tcttggtcat     1020

cccaaaacca aagcttttat cactcatggt ggaatgaatg ggatctatga agctatttac     1080

catggggtcc ctatggtggg agttcccata tttggtgatc agcttgataa catagctcac     1140

atgaaggcca aaggagcagc tgtagaaata aacttcaaaa ctatgacaag cgaagattta     1200

ctgagggctt tgagaacagt cattaccgat tcctcttata aagagaatgc tatgagatta     1260

tcaagaattc accatgatca acctgtaaag cccctagatc gagcagtctt ctggatcgag     1320

tttgtcatgc gccacaaagg agccaagcac ctgcgatcag ctgcccatga cctcacctgg     1380

ttccagcact actctataga tgtg                                            1404


<210>  5639
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5639
cagggaggac aggttgactg tggtgagttc caggacacca aggtctactg cactcgggaa       60

tctaacccac actgtggctc tgatggccag acatatggca ataaatgtgc cttctgtaag      120

gccatagtga aaagtggtgg aaagattagc ctaaagcatc ctggaaaatg c               171


<210>  5640
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  5640
aaaatctaca ctcgttgcaa actggcaaaa atattctcga gggctggcct ggacaattac       60

tggggcttca gccttggaaa ctggatctgc atggcatatt atgagagcgg ctacaacacc      120

acagccccga cggtcctgga tgacggcagc atcgactatg gcatcttcca gatcaacagc      180

ttcgcgtggt gcagacgcgg aaagctgaag gagaacaacc actgccatgt cgcctgctca      240

gccttgatca ctgatgacct cacagatgca attatctgtg ccaggaaaat tgttaaagag      300

acacaaggaa tgaactattg gcaaggctgg aagaaacatt gtgagggcag agacctgtcc      360

gagtggaaaa aaggctgtga ggtttcc                                          387


<210>  5641
<211>  1191
<212>  DNA
<213>  Homo Sapiens

<400>  5641
cgccggaagc tgctggtgtt tctgctggat ggttttcgct cagactacat cagtgatgag       60

gcgctggagt cattgcctgg tttcaaagag attgtgagca ggggagtaaa agtggattac      120

ttgactccag acttccctag tctctcgtat cccaattatt ataccctaat gactggccgc      180

cattgtgaag tccatcagat gatcgggaac tacatgtggg accccaccac caacaagtcc      240

tttgacattg gcgtcaacaa agacagccta atgcctctct ggtggaatgg atcagaacct      300

ctgtgggtca ctctgaccaa ggccaaaagg aaggtctaca tgtactactg gccaggctgt      360

gaggttgaga ttctgggtgt cagacccacc tactgcctag aatataaaaa tgtcccaacg      420

gatatcaatt ttgccaatgc agtcagcgat gctcttgact ccttcaagag tggccgggcc      480

gacctggcag ccatatacca tgagcgcatt gacgtggaag gccaccacta cgggcctgca      540

tctccgcaga ggaaagatgc cctcaaggct gtagacactg tcctgaagta catgaccaag      600

tggatccagg agcggggcct gcaggaccgc ctgaacgtca ttattttctc ggatcacgga      660

atgaccgaca ttttctggat ggacaaagtg attgagctga ataagtacat cagcctgaat      720

gacctgcagc aagtgaagga ccgcgggcct gttgtgagcc tttggccggc ccctgggaaa      780

cactctgaga tatataacaa actgagcaca gtggaacaca tgactgtcta cgagaaagaa      840

gccatcccaa gcaggttcta ttacaagaaa ggaaagtttg tctctccttt gactttagtg      900

gctgatgaag gctggttcat aactgagaat cgagagatgc ttccgttttg gatgaacagc      960

accggcaggc gggaaggttg gcagcgtgga tggcacggct acgacaacga gctcatggac     1020

atgcggggca tcttcctggc cttcggacct gatttcaaat ccaacttcag agctgctcct     1080

atcaggtcgg tggacgtcta caatgtcatg tgcaatgtgg tgggcatcac cccgctgccc     1140

aacaacggat cctggtccag ggtgatgtgc atgctgaagg gccgcgccag c              1191


<210>  5642
<211>  804
<212>  DNA
<213>  Homo Sapiens

<400>  5642
caacctttca gcccattagc acctgagcca gtgctttctg gagctcacac ctggcgctca       60

ctcatccatc acattaggct gatgtccttg cccattgcca agaagtacat gtcagaaaat      120

aagggagttc ctctgcatgg gggtgatgaa gacagaccct ttccagactt tgacccctgg      180

tggacaaacg actgtgagca gaatgagtca gagcccattc ctgccaactg cactggctgt      240

gcccagaaac acctgaaggt gatgctcctg gaagacgccc caaggaaatt tgagaggctc      300

catccactgg tgatcaagac gggaaagccc ctgttggagg aagagattca gcattttttg      360

tgccagtacc ctgaggcgac agaaggcttc tctgaagggt ttttcgccaa gtggtggcgc      420

tgctttcctg agcggtggtt cccatttcct tatccatgga ggagacctct gaacagatca      480

caaatgttac gtgagctttt tcctgttttc actcacctgc catttccaaa agatgcctct      540

ttaaacaagt gctcctttct tcacccagaa cctgttgtgg ggagtaagat gcataagatg      600

cctgacctat ttatcattgg cagcggtgag gccatgttgc agctcatccc tcccttccag      660

tgccgaagac attgtcagtc tgtggccatg ccaatagagc caggggatat cggctatgtc      720

gacaccaccc actggaaggt ctacgttata gccagagggg tccagccttt ggtcatctgc      780

gatggaaccg ctttctcaga actg                                             804


<210>  5643
<211>  1236
<212>  DNA
<213>  Homo Sapiens

<400>  5643
gcaccggtac aaagtcaggg ctcccagaac aagctgctcc tggtgtcctt cgacggcttc       60

cgctggaact acgaccagga cgtggacacc cccaacctgg acgccatggc ccgagacggg      120

gtgaaggcac gctacatgac ccccgccttt gtcaccatga ccagcccctg ccacttcacc      180

ctggtcaccg gcaaatatat cgagaaccac ggggtggttc acaacatgta ctacaacacc      240

accagcaagg tgaagctgcc ctaccacgcc acgctgggca tccagaggtg gtgggacaac      300

ggcagcgtgc ccatctggat cacagcccag aggcagggcc tgagggctgg ctccttcttc      360

tacccgggcg ggaacgtcac ctaccaaggg gtggctgtga cgcggagccg gaaagaaggc      420

atcgcacaca actacaaaaa tgagacggag tggagagcga acatcgacac agtgatggcg      480

tggttcacag aggaggacct ggatctggtc acactctact tcggggagcc ggactccacg      540

ggccacaggt acggccccga gtccccggag aggagggaga tggtgcggca ggtggaccgg      600

accgtgggct acctccggga gagcatcgcg cgcaaccacc tcacagaccg cctcaacctg      660

atcatcacat ccgaccacgg catgacgacc gtggacaaac gggctggcga cctggttgaa      720

ttccacaagt tccccaactt caccttccgg gacatcgagt ttgagctcct ggactacgga      780

ccaaacggga tgctgctccc taaagaaggg aggctggaga aggtgtacga tgccctcaag      840

gacgcccacc ccaagctcca cgtctacaag aaggaggcgt tccccgaggc cttccactac      900

gccaacaacc ccagggtcac acccctgctg atgtacagcg accttggcta cgtcatccat      960

gggagaatta acgtccagtt caacaatggg gagcacggct ttgacaacaa ggacatggac     1020

atgaagacca tcttccgcgc tgtgggccct agcttcaggg cgggcctgga ggtggagccc     1080

tttgagagcg tccacgtgta cgagctcatg tgccggctgc tgggcatcgt gcccgaggcc     1140

aacgatgggc acctagctac tctgctgccc atgctgcaca cagaatctgc tcttccgcct     1200

gatggaaggc ctactctcct gcccaaggga agatct                               1236


<210>  5644
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  5644
gaggttctgc tgcagcctga cttcaatgct gaaaagttct caggcctctg gtacgtggtc       60

tccatggcat ctgactgcag ggtcttcctg ggcaagaagg accacctgtc catgtccacc      120

agggccatca ggcccacaga ggagggcggc ctccacgtcc acatggagtt cccgggggcg      180

gacggctgta accaggtgga tgccgagtac ctgaaggtgg gctccgaggg acacttcaga      240

gtcccggcct tgggctacct ggacgtgcgc atcgtggaca cagactacag ctccttcgcc      300

gtcctttaca tctacaagga gctggagggg gccctcagca ccatggtgca gctctacagc      360

cggacccagg atgtgagtcc ccaggctctg aagtccttcc aggacttcta cccgaccctg      420

gggctcccca aggacatgat ggtcatgctg ccccagtcag atgcatgcaa ccctgagagc      480

aaggaggcgc cc                                                          492


<210>  5645
<211>  1626
<212>  DNA
<213>  Homo Sapiens

<400>  5645
actgggcccg aagttgctca gcctgaagta gacaccaccc tgggtcgtgt gcgaggccgg       60

caggtgggcg tgaagggcac agaccgcctt gtgaatgtct ttctgggcat tccatttgcc      120

cagccgccac tgggccctga ccggttctca gccccacacc cagcacagcc ctgggagggt      180

gtgcgggatg ccagcactgc gcccccaatg tgcctacaag acgtggagag catgaacagc      240

agcagatttg tcctcaacgg aaaacagcag atcttctccg tttcagagga ctgcctggtc      300

ctcaacgtct atagcccagc tgaggtcccc gcagggtccg gtaggccggt catggtatgg      360

gtccatggag gcgctctgat aactggcgct gccacctcct acgatggatc agctctggct      420

gcctatgggg atgtggtcgt ggttacagtc cagtaccgcc ttggggtcct tggcttcttc      480

agcactggag atgagcatgc acctggcaac cagggcttcc tagatgtggt agctgctttg      540

cgctgggtgc aagaaaacat cgcccccttc gggggtgacc tcaactgtgt cactgtcttt      600

ggtggatctg ccggtgggag catcatctct ggcctggtcc tgtccccagt ggctgcaggg      660

ctgttccaca gagccatcac acagagtggg gtcatcacca ccccagggat catcgactct      720

cacccttggc ccctagctca gaaaatcgca aacaccttgg cctgcagctc cagctccccg      780

gctgagatgg tgcagtgcct tcagcagaaa gaaggagaag agctggtcct tagcaagaag      840

ctgaaaaata ctatctatcc tctcaccgtt gatggcactg tcttccccaa aagccccaag      900

gaactcctga aggagaagcc cttccactct gtgcccttcc tcatgggtgt caacaaccat      960

gagttcagct ggctcatccc caggggctgg ggtctcctgg atacaatgga gcagatgagc     1020

cgggaggaca tgctggccat ctcaacaccc gtcttgacca gtctggatgt gccccctgag     1080

atgatgccca ccgtcataga tgaataccta ggaagcaact cggacgcaca agccaaatgc     1140

caggcgttcc aggaattcat gggtgacgta ttcatcaatg ttcccaccgt cagtttttca     1200

agataccttc gagattctgg aagccctgtc tttttctatg agttccagca tcgacccagt     1260

tcttttgcga agatcaaacc tgcctgggtg aaggctgatc atggggccga gggtgctttt     1320

gtgttcggag gtcccttcct catggacgag agctcccgcc tggaggccac agaggaggag     1380

aagcagctaa gcctcaccat gatggcccag tggacccact ttgcccggac aggggacccc     1440

aatagcaagg ctctgcctcc ttggccccaa ttcaaccagg cggaacaata tctggagatc     1500

aacccagtgc cacgggccgg acagaagttc agggaggcct ggatgcagtt ctggtcagag     1560

acgctcccca gcaagataca acagtggcac cagaagcaga agaacaggaa ggcccaggag     1620

gacctc                                                                1626


<210>  5646
<211>  1542
<212>  DNA
<213>  Homo Sapiens

<400>  5646
gagcagaggc ggagagcagc caaagcgccc aatgtggtgc tggtcgtgag cgactccttc       60

gatggaaggt taacatttca tccaggaagt caggtagtga aacttccttt tatcaacttt      120

atgaagacac gtgggacttc ctttctgaat gcctacacaa actctccaat ttgttgccca      180

tcacgcgcag caatgtggag tggcctcttc actcacttaa cagaatcttg gaataatttt      240

aagggtctag atccaaatta tacaacatgg atggatgtca tggagaggca tggctaccga      300

acacagaaat ttgggaaact ggactatact tcaggacatc actccattag taatcgtgtg      360

gaagcgtgga caagagatgt tgctttctta ctcagacaag aaggcaggcc catggttaat      420

cttatccgta acaggactaa agtcagagtg atggaaaggg attggcagaa tacagacaaa      480

gcagtaaact ggttaagaaa ggaagcaatt aattacactg aaccatttgt tatttacttg      540

ggattaaatt taccacaccc ttacccttca ccatcttctg gagaaaattt tggatcttca      600

acatttcaca catctcttta ttggcttgaa aaagtgtctc atgatgccat caaaatccca      660

aagtggtcac ctttgtcaga aatgcaccct gtagattatt actcttctta tacaaaaaac      720

tgcactggaa gatttacaaa aaaagaaatt aagaatatta gagcatttta ttatgctatg      780

tgtgctgaga cagatgccat gcttggtgaa attattttgg cccttcatca attagatctt      840

cttcagaaaa ctattgtcat atactcctca gaccatggag agctggccat ggaacatcga      900

cagttttata aaatgagcat gtacgaggct agtgcacatg ttccgctttt gatgatggga      960

ccaggaatta aagccggcct acaagtatca aatgtggttt ctcttgtgga tatttaccct     1020

accatgcttg atattgctgg aattcctctg cctcagaacc tgagtggata ctctttgttg     1080

ccgttatcat cagaaacatt taagaatgaa cataaagtca aaaacctgca tccaccctgg     1140

attctgagtg aattccatgg atgtaatgtg aatgcctcca cctacatgct tcgaactaac     1200

cactggaaat atatagccta ttcggatggt gcatcaatat tgcctcaact ctttgatctt     1260

tcctcggatc cagatgaatt aacaaatgtt gctgtaaaat ttccagaaat tacttattct     1320

ttggatcaga agcttcattc cattataaac taccctaaag tttctgcttc tgtccaccag     1380

tataataaag agcagtttat caagtggaaa caaagtatag gacagaatta ttcaaacgtt     1440

atagcaaatc ttaggtggca ccaagactgg cagaaggaac caaggaagta tgaaaatgca     1500

attgatcagt ggcttaaaac ccatatgaat ccaagagcag tt                        1542


<210>  5647
<211>  756
<212>  DNA
<213>  Homo Sapiens

<400>  5647
gcccagatca tcgggggcca cgaggtgacc ccccactcca ggccctacat ggcatccgtg       60

cgcttcgggg gccaacatca ctgcggaggc ttcctgctgc gagcccgctg ggtggtctcg      120

gccgcccact gcttcagcca cagagacctc cgcactggcc tggtggtgct gggcgcccac      180

gtcctgagta ctgcggagcc cacccagcag gtgtttggca tcgatgctct caccacgcac      240

cccgactacc accccatgac ccacgccaac gacatctgcc tgctgcggct gaacggctct      300

gctgtcctgg gccctgcagt ggggctgctg aggctgccag ggagaagggc caggcccccc      360

acagcgggga cacggtgccg ggtggctggc tggggcttcg tgtctgactt tgaggagctg      420

ccgcctggac tgatggaggc caaggtccga gtgctggacc cggacgtctg caacagctcc      480

tggaagggcc acctgacact taccatgctc tgcacccgca gtggggacag ccacagacgg      540

ggcttctgct cggccgactc cggagggccc ctggtgtgca ggaaccgggc tcacggcctc      600

gtttccttct cgggcctctg gtgcggcgac cccaagaccc ccgacgtgta cacgcaggtg      660

tccgcctttg tggcctggat ctgggacgtg gttcggcgga gcagtcccca gcccggcccc      720

ctgcctggga ccaccaggcc cccaggagaa gccgcc                                756


<210>  5648
<211>  1122
<212>  DNA
<213>  Homo Sapiens

<400>  5648
ccagccatgg tgcattacat ctaccagcgc tttcgagtct tggagcaagg gctggaaaaa       60

tgtacccaag caacgagggc atacattcaa gaattccaag agttctcaaa aaatatatct      120

gtcatgctgg gaagatgtca gacctacaca agtgagtaca agagtgcagt gggtaacttg      180

gcactgagag ttgaacgtgc ccaacgggag attgactaca tacaatacct tcgagaggct      240

gacgagtgca tcgtatcaga ggacaagaca ctggcagaaa tgttgctcca agaagctgaa      300

gaagagaaaa agatccggac tctgctgaat gcaagctgtg acaacatgct gatgggcata      360

aagtctttga aaatagtgaa gaagatgatg gacacacatg gctcttggat gaaagatgct      420

gtctataact ctccaaaggt gtacttatta attggatcca gaaacaacac tgtttgggaa      480

tttgcaaaca tacgggcatt catggaggat aacaccaagc cagctccccg gaagcaaatc      540

ctaacacttt cctggcaggg aacaggccaa gtgatctaca aaggttttct attttttcat      600

aaccaagcaa cttctaatga gataatcaaa tataacctgc agaagaggac tgtggaagat      660

cgaatgctgc tcccaggagg ggtaggccga gcattggttt accagcactc cccctcaact      720

tacattgacc tggctgtgga tgagcatggg ctctgggcca tccactctgg gccaggcacc      780

catagccatt tggttctcac aaagattgag ccgggcacac tgggagtgga gcattcatgg      840

gataccccat gcagaagcca ggatgctgaa gcctcattcc tcttgtgtgg ggttctctat      900

gtggtctaca gtactggggg ccagggccct catcgcatca cctgcatcta tgatccactg      960

ggcactatca gtgaggagga cttgcccaac ttgttcttcc ccaagagacc aagaagtcac     1020

tccatgatcc attacaaccc cagagataag cagctctatg cctggaatga aggaaaccag     1080

atcatttaca aactccagac aaagagaaag ctgcctctga ag                        1122


<210>  5649
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  5649
gatttggggg atgtgggacc tccaattccc agccccggct tcagctcttt cccaggtgtt       60

gactccagct ccagcttcag ctccagctcc aggtcgggct ccagctccag ccgcagctta      120

ggcagcggag gttctgtgtc ccagttgttt tccaatttca ccggctccgt ggatgaccgt      180

gggacctgcc agtgctctgt ttccctgcca gacaccacct ttcccgtgga cagagtggaa      240

cgcttggaat tcacagctca tgttctttct cagaagtttg agaaagaact ttccaaagtg      300

agggaatatg tccaattaat tagtgtgtat gaaaagaaac tgttaaacct aactgtccga      360

attgacatca tggagaagga taccatttct tacactgaac tggacttcga gctgatcaag      420

gtagaagtga aggagatgga aaaactggtc atacagctga aggagagttt tggtggaagc      480

tcagaaattg ttgaccagct ggaggtggag ataagaaata tgactctctt ggtagagaag      540

cttgagacac tagacaaaaa caatgtcctt gccattcgcc gagaaatcgt ggctctgaag      600

accaagctga aagagtgtga ggcctctaaa gatcaaaaca cccctgtcgt ccaccctcct      660

cccactccag ggagctgtgg tcatggtggt gtggtgaaca tcagcaaacc gtctgtggtt      720

cagctcaact ggagagggtt ttcttatcta tatggtgctt ggggtaggga ttactctccc      780

cagcatccaa acaaaggact gtattgggtg gcgccattga atacagatgg gagactgttg      840

gagtattata gactgtacaa cacactggat gatttgctat tgtatataaa tgctcgagag      900

ttgcggatca cctatggcca aggtagtggt acagcagttt acaacaacaa catgtacgtc      960

aacatgtaca acaccgggaa tattgccaga gttaacctga ccaccaacac gattgctgtg     1020

actcaaactc tccctaatgc tgcctataat aaccgctttt catatgctaa tgttgcttgg     1080

caagatattg actttgctgt ggatgagaat ggattgtggg ttatttattc aactgaagcc     1140

agcactggta acatggtgat tagtaaactc aatgacacca cacttcaggt gctaaacact     1200

tggtatacca agcagtataa accatctgct tctaacgcct tcatggtatg tggggttctg     1260

tatgccaccc gtactatgaa caccagaaca gaagagattt tttactatta tgacacaaac     1320

acagggaaag agggcaaact agacattgta atgcataaga tgcaggaaaa agtgcagagc     1380

attaactata acccttttga ccagaaactt tatgtctata acgatggtta ccttctgaat     1440

tatgatcttt ctgtcttgca gaagccccag                                      1470


<210>  5650
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  5650
gacgatgttc cacaggagcc cgtgcccacg ctgtggaacg agccggccga gctgccgtcg       60

ggagaaggcc ccgtggagag caccagcccc ggccgggagc ccgtggacac cggtccccca      120

gcccccaccg tcgcgccagg acccgaggac agcaccgcgc aggagcggct ggaccagggc      180

ggcgggtcgc tggggcccgg cgct                                             204


<210>  5651
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  5651
ttaccacagc tcaaacctgc tttgggactc cctcccacaa aactggctcc ggatcaggga       60

acactaccaa accaacagca gtcaaatcag gtctttcctt ctttaagtct gataccatta      120

acacagatgc tcacactggg gccagatctg catctgttaa atcctgctgc aggaatgaca      180

cctggtaccc agacccaccc attgaccctg ggagggttga atgtacaaca gcaactgcac      240

ccacatgtgt taccaatttt tgtcacacaa cttggagccc agggcactat cctaagctca      300

gaggaattgc cacaaatctt cacgagcctc atcatccatt ccttgttccc gggaggcatc      360

ctgcccacca gtcaggcagg ggctaatcca gatgtccagg atggaagcct tccagcagga      420

ggagcaggtg taaatcctgc cacccaggga accccagcag gccgcctccc aactcccagt      480

ggcacagatg acgactttgc agtgaccacc cctgcaggca tccaaaggag cacacatgcc      540

attgaggaag ccaccacaga atcagcaaat ggaattcag                             579


<210>  5652
<211>  1125
<212>  DNA
<213>  Homo Sapiens

<400>  5652
aaacccggag accaaatcct tgattggcag tatggagtta ctcaggcctt ccctcacaca       60

gaggaggagg tggaagttga ttcacacgcg tacagccaca ggtggaaaag aaacttggac      120

tttctcaagg cggtagacac gaaccgagca agcgtcggcc aagactctcc tgagcccaga      180

agcttcacag acctgctgct ggatgatggg caggacaata acactcagat cgagagagtg      240

aatctgtcct tcgattttcc attttatggc cacttcctac gtgaaatcac tgtggcaacc      300

gggggtttca tatacactgg agaagtcgta catcgaatgc taacagccac acagtacata      360

gcacctttaa tggcaaattt cgatcccagt gtatccagaa attcaactgt cagatatttt      420

gataatggca cagcacttgt ggtccagtgg gaccatgtac atctccagga taattataac      480

ctgggaagct tcacattcca ggcaaccctg ctcatggatg gacgaatcat ctttggatac      540

aaagaaattc ctgtcttggt cacacagata agttcaacca atcatccagt gaaagtcgga      600

ctgtccgatg catttgtcgt tgtccacagg atccaacaaa ttcccaatgt tcgaagaaga      660

acaatttatg aataccaccg agtagagcta caaatgtcaa aaattaccaa catttcggct      720

gtggagatga ccccattacc cacatgcctc cagtttaaca gatgtggccc ctgtgtatct      780

tctcagattg gcttcaactg cagttggtgt agtaaacttc aaagatgttc cagtggattt      840

gatcgtcatc ggcaggactg ggtggacagt ggatgccctg aagagtcaaa agagaagatg      900

tgtgagaata cagaaccagt ggaaacttct tctcgaacca ccacaaccgt aggagcgaca      960

accacccagt tcagggtcct aactaccacc agaagagcag tgacttctca gtttcccacc     1020

agcctcccta cagaagatga taccaagata gcactacatc taaaagataa tggagcttct     1080

acagatgaca gtgcagctga gaagaaaggg ggaaccctcc acgct                     1125


<210>  5653
<211>  897
<212>  DNA
<213>  Homo Sapiens

<400>  5653
cggagcatcg gtgttgtgga ggagaaagtt tcccaaaact tggggaccaa cttgcctcag       60

ctcggacaac cttcctccac tggcccctct aactctgaac atccgcagcc cgctctggac      120

cctaggtcta atgacttggc aagggttcct ctgaagctca gcgtgcctgc atcagatggc      180

ttcccacctg caggaggttc tgcagtgcag aggtggcctc catcgtgggg gctgcctgcc      240

atggattcct ggccccctga ggatccttgg cagatgatgg ctgctgcggc tgaggaccgc      300

ctgggggaag cgctgcctga agaactctct tacctctcca gtgctgcggc cctcgctccg      360

ggcagtggcc ctttgcctgg ggagtcttct cccgatgcca caggcctctc acccaaggct      420

tcactcctcc accaggactc ggagtccaga cgactgcccc gttctaattc actgggagcc      480

gggggaaaaa tcctttccca acgccctccc tggtctctca tccacagggt tctgcctgat      540

cacccctggg gtaccctgaa tcccagtgtg tcctggggag gtggaggccc tgggactggt      600

tggggaacga ggcccatgcc acaccctgag ggaatctggg gtatcaataa tcaaccccca      660

ggtaccagct ggggaaatat taatcggtat ccaggaggca gctggggaaa tattaatcgg      720

tatccaggag gcagctgggg gaatattaat cggtatccag gaggcagctg ggggaatatt      780

catctatacc caggtatcaa taacccattt cctcctggag tcctccgccc tcctggctct      840

tcttggaaca tcccagctgg cttccctaat cctccaagcc ctaggttgca gtggggc         897


<210>  5654
<211>  258
<212>  DNA
<213>  Homo Sapiens

<400>  5654
tgctgcatga agaggaagaa gaagaccgcc aacccggaga acaacctgag ctactggaac       60

aacaccatca ccatggacta cttcaacagg catgctgtgg agctgcccag ggagatccag      120

tcccttgaaa cctctgagga ccagctctca gagccccgct ccccagccaa tggcgactat      180

agagacactg ggatggtcct tgttaacccc ttctgtcaag aaacactgtt tgtgggaaac      240

gatcaagtat ctgagatc                                                    258


<210>  5655
<211>  1893
<212>  DNA
<213>  Homo Sapiens

<400>  5655
aacaaagaaa cggcaaagaa gattaaaagg cccaagttca ctgtgcctca gatcaactgc       60

gatgtcaaag ccggaaagat catcgatcct gagttcattg tgaaatgtcc agcaggatgc      120

caagacccca aataccatgt ttatggcact gacgtgtatg catcctactc cagtgtgtgt      180

ggcgctgccg tacacagtgg tgtgcttgat aattcaggag ggaaaatact tgttcggaag      240

gttgctggac agtctggtta caaagggagt tattccaacg gtgtccaatc gttatcccta      300

ccacgatgga gagaatcctt tatcgtctta gaaagtaaac ccaaaaaggg tgtaacctac      360

ccatcagctc ttacatactc atcatcgaaa agtccagctg cccaagcagg tgagaccaca      420

aaagcctatc agaggccacc tattccaggg acaactgcac agccggtcac tctgatgcag      480

cttctggctg tcactgtagc tgtggccacc cccaccacct tgccaaggcc atccccttct      540

gctgcttcta ccaccagcat ccccagacca caatcagtgg gccacaggag ccaggagatg      600

gatctctggt ccactgccac ctacacaagc agccaaaaca ggcccagagc tgatccaggt      660

atccaaaggc aagatccttc aggagctgcc ttccagaaac ctgttggagc ggatgtcagc      720

ctggactgca aaattgactt gtcgttttta attgatggga gcaccagcat tggcaaacgg      780

cgattccgaa tccagaagca gctcctggct gatgttgccc aagctcttga cattggccct      840

gccggtccac tgatgggtgt tgtccagtat ggagacaacc ctgctactca ctttaacctc      900

aagacacaca cgaactctcg agatctgaag acagccatag agaaaattac tcagagagga      960

ggactttcta atgtaggtcg ggccatctcc tttgtgacca agaacttctt ttccaaagcc     1020

aatggaaaca gaagcggggc tcccaatgtg gtggtggtga tggtggatgg ctggcccacg     1080

gacaaagtgg aggaggcttc aagacttgcg agagagtcag gaatcaacat tttcttcatc     1140

accattgaag gtgctgctga aaatgagaag cagtatgtgg tggagcccaa ctttgcaaac     1200

aaggccgtgt gcagaacaaa cggcttctac tcgctccacg tgcagagctg gtttggcctc     1260

cacaagaccc tgcagcctct ggtgaagcgg gtctgcgaca ctgaccgcct ggcctgcagc     1320

aagacctgct tgaactcggc tgacattggc ttcgtcatcg acggctccag cagtgtgggg     1380

acgggcaact tccgcaccgt cctccagttt gtgaccaacc tcaccaaaga gtttgagatt     1440

tccgacacgg acacgcgcat cggggccgtg cagtacacct acgaacagcg gctggagttt     1500

gggttcgaca agtacagcag caggcctgac atcatcaacg ccatcaagag ggtgggctac     1560

tggagtggtg gcaccagcac gggggctgcc atcaacttcg ccctggagca gctcttcaag     1620

aagtccaagc ccaacaagag gaagttaatg atcctcatca ccgacgggag gtcctacgac     1680

gacgtccgga tcccagccat ggctgcccat ctgaagggag tgatcaccta tgcgataggc     1740

gttgcctggg ctgcccaaga ggagctagaa gtcattgcca ctcaccccgc cagagaccac     1800

tccttctttg tggacgagtt tgacaacctc tatcagtatg tccccaggat catccagaac     1860

atttgtacag agttcaactc acagcctcgg aac                                  1893


<210>  5656
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  5656
gccacagtaa gaaatgagga caaatggaag ccactcaaca accccagaaa cagagatctg       60

tttttcagaa ggcttcaggc atattttaag ggcagaggtc ttgatcttgg aacatttcca      120

aatcctttcc ccacgaatga aaatcctaga cctctctctt tccagtcaga acttactgct      180

tctgcatctg cagattatga agagcagaaa aactcctttc acaattatct caaaggc         237


<210>  5657
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  5657
aggccccggg ggcgcagggg agcgcgcgtc acggataagg agcccaagcc gttgcttttc       60

ctccccgcgg ccggggccgg ccggactccc agcggctccc ggagcgcaga aatattccca      120

agagactcta acttaaaaga caaattcata aagcatttca cagggccggt cacattttca      180

ccagaatgca gcaaacattt ccaccgactc tattacaata ccagggagtg ctcaacgcca      240

gcttattaca aaagatgtgc tagattgtta acaagattag cagtgagtcc actgtgctcc      300

cagacc                                                                 306


<210>  5658
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  5658
cggctccggg gaccctgggg gcgcgccgtc ggagagagga ccctgccggg ggcccaagac       60

cgagacgacg gggaggaggc ggacggcgga ggcccggcgg accagttcag cgacgggcgc      120

gagccactgc cgggagggtg cagccttgtt tgcaagccgt cggccctggc ccagtgcctg      180

ctgcgcgccc tgcggcgctc agaggcgctg gaggccggcc cgcgctcctg gttctccggg      240

ccccacctgc agaccctctg ccacttcgtc ctgcccgtag cgcctgggcc tgagctggcc      300

cgggagtacc tgcagttggc ggacgatggg ctagtggccc tggactgggt ggtaggacct      360

tgtgttcggg gccgccggat caccagcgcc gggggccttc ctgcggtgct tctggtgatc      420

cccaatgcgt ggggtcgcct cacccgcaac gtgctcggcc tttgcttgct cgccctggag      480

cgcggctact acccggtcat cttccatcgc cgcggccacc acggttgccc actggtcagc      540

ccccggctgc agcctttcgg ggacccgtcc gacctcaagg aggcggtcac atacatccgc      600

ttccgacacc cggcggcgcc gctgttcgcg gtgagcgaag gctcgggctc ggcgctgctc      660

ctgtcctacc tgggcgagtg cggctcctcc agctacgtga caggcgccgc ctgcatctcg      720

cccgtgctgc gctgccgaga gtggttcgag gccggcctgc cctggcccta cgagcggggc      780

tttctgctct accagaagat cgccctcagc aggtatgcca cagccctgga ggacactgtg      840

gacaccagca gactgttcag gagccgttcc cttcgagagt ttgaggaggc tctcttctgc      900

cacaccaaaa gcttccccat cagctgggat gcctactggg accgcaacga cccgctccgg      960

gatgtcgatg aggcagccgt gcctgtgctg tgtatctgca gtgctgacga ccccgtgtgt     1020

ggacccccag accacactct gacaactgaa ctcttccaca gcaaccccta cttcttcctc     1080

ctgctcagtc gccacggagg ccactgtggc ttcctgcgcc aggagccctt gccagcctgg     1140

agccatgagg tcatcttgga gtccttccgg gccttgactg agttcttccg aacggaggag     1200

aggattaaag ggctgagcag gcacagagct tccttccttg ggggccgtcg tcgtggggga     1260

gccttgcaga ggcgggaagt ctcttcctct tccaacctgg aggagatctt taactggaag     1320

cgatcataca caagg                                                      1335


<210>  5659
<211>  3870
<212>  DNA
<213>  Homo Sapiens

<400>  5659
ggaccccctg tccccgcttc atcaagcaca aagttgttaa tgacaagcta ttctatgcgc       60

tccacggtgg tgtctcgcta tgcccacacc ttggtcacct ctgtcctgtt taatccacat      120

gctgaagccc atgaagccat ctttgacctg gatctgcctc atcttgcctt tatctccaat      180

ttcactatga ccatcaacaa taaagtctac attgcagaag tcaaagagaa gcaccaggca      240

aagaaaatct atgaagaagc ccatcagcag ggaaagacag ctgctcatgt aggcatcagg      300

gaccgggaat cagagaagtt ccgcatctcc accagcctgg cagcaggcac agaggtgact      360

ttttccctgg cctatgagga actgcttcag cggcaccagg gccagtacca gctggtggtg      420

agcctgaggc ctggccaatt ggtgaagagg ctgagcatag aggttacagt gtcagaaagg      480

acaggcatct cctatgtgca cataccaccc ctgaggaccg gccgtctgcg caccaatgcc      540

catgcaagtg aggtggattc acccccatcc accaggatcg agaggggaga gacctgtgtc      600

cgaatcacct actgcccgac attgcaagac cagtcgtcca tctctgggtc aggcatcatg      660

gctgacttcc tggttcagta cgatgtggtc atggaggaca tcattggaga cgtgcagatt      720

tacgatgact atttcattca ctactttgcc cccagaggcc ttccacctat ggagaagaat      780

gtggtttttg ttattgacgt aagcagctcc atgtttggta ccaagatgga acagactaaa      840

acggccatga atgtgatcct cagtgacctt caagccaatg actacttcaa catcatctcc      900

ttttctgaca cagttaatgt ttggaaagct ggaggctcaa tccaggccac catccagaat      960

gtccacagtg ccaaggacta cctgcattgc atggaagccg atggctggac agacgtcaac     1020

tcagctctgc tggcagctgc ttcagtgctg aaccatagca accaggagcc tgggaggggc     1080

cccagtgtgg ggaggatccc tcttatcatc ttcctgacgg atggggagcc cacggccggc     1140

gtgacgaccc ccagtgtgat cctctccaat gtccgtcagg cgctaggcca cagggtatcc     1200

cttttcagct tggcctttgg ggatgatgct gactttacac tgctgcgccg cctgtccctg     1260

gaaaaccggg gaatagcccg gcgcatatat gaggacactg atgcggccct acagctgaag     1320

ggcctctatg aggagatctc catgcctctg ctggcagatg tgcgtctgaa ctacctgggt     1380

ggcttggttg gggcctcccc ttgggccgtt ttccccaact actttggtgg ctctgagctg     1440

gtggtggcag gacaggtgca gccaggcaaa caggaactgg gcatccacct ggcagcccgt     1500

ggccccaagg atcagcttct tgtggcccac cacagtgaag gggccaccaa caacagccag     1560

aaggcctttg gttgcccagg ggagccagcc cccaatgtgg cccacttcat ccgccgcctc     1620

tgggcctatg tcaccattgg agaactgctg gatgcacact tccaagctcg tgacaccacc     1680

actcgccacc tgctggctgc caaagtcctc aacctgtccc ttgaatacaa ctttgtcaca     1740

cctctgactt cactggtcat ggtgcaaccc aaacaggcca gtgaggagac caggagacag     1800

acttccacct ctgctgggcc agacaccatc atgccctcat ccagcagcag gcatggccta     1860

ggggtaagca cagctcagcc agccttggtg cccaaggtca tctcccccaa atcaaggcct     1920

gtgaaaccaa agttctactt atcctcaact actactgcct ctaccaagaa gatgctaagt     1980

tccaaagagc tggagccatt gggagagagc cctcataccc tgtcaatgcc cacataccca     2040

aaggccaaaa ttccagcaca acaggattct ggcaccttgg cccagccaac tctcaggaca     2100

aaacctacca ttcttgtgcc ctcaaattct ggtactctgt tgcctctgaa gcccggctct     2160

ctatcacacc agaatcctga tatattaccc acgaactcca ggacacaagt cccacctgtg     2220

aaacctggca tcccagcctc gcccaaagct gacactgtga aatgtgttac tccactgcat     2280

tccaaacctg gtgctccatc gcacccccaa cttggggcac tcacatcaca ggcacctaaa     2340

ggcctgccac agtcaagacc tggagtctct acacttcagg ttcccaagta cccactacac     2400

accagaccta gggttcctgc tcccaagacc cgaaacaaca tgccacacct ggggcctgga     2460

atcctcttgt ccaagacccc taaaatctta ttatctctta aaccgagtgc cccaccacac     2520

caaatttcca caagcatatc actttccaag cctgagaccc caaaccccca tatgcctcaa     2580

accccactac ctcctagacc tgacagacca aggcccccac ttcctgagag cctaagcaca     2640

ttcccaaata caatctcaag ttccacaggt cccagcagta ccacaaccac ctctgtcctt     2700

ggagaacccc tccccatgcc ctttactccc actctgcccc ctggaaggtt ctggcatcag     2760

tatgacctcc tcccgggtcc ccagaggacc aggcaagttc tgggaccatc taggccagga     2820

gttccaacaa tgagcctact caacagctcc aggcctacac cagaaggcag ccctccaaac     2880

ctgccaatct tgctgccttc tagcatcctc cctgaggcca tcagtctgct ccttctccct     2940

gaggagctag agctgctgtc tgaatcaatg gtggaatcca agttcgtgga gtccttgaac     3000

ccaccagctt tctatacctt cctcactcct gatgaagatg gaagtccaaa ctgggatggc     3060

aattctgagg agatcctggg aggagctgga ggcagcatgg aatctcaagg aagttctgtg     3120

gggttagcaa aaggcacatt gcctagcatc ttcaccttct cctcctcagt ggacggggac     3180

ccccactttg tgatccaaat cccacactca gaagagaaga tctgcttcac actgaatggg     3240

caccctgggg acttgctgca gctcatagag gacccaaagg cagggctgca tgtgagtggg     3300

aagctgcttg gcgcaccacc aaggccgggc cacaaggacc agactcgcac ctacttccag     3360

atcatcacag tcactacaga caaaccccgg gcctatacta tcaccatcag ccgcagttct     3420

atatctttgc gaggcgaggg taccttgcgc ctgtcctggg accaacctgc cctgctgaag     3480

aggccccagc tggagctcta tgtggctgct gcagcccgcc ttaccctccg ccttgggccc     3540

taccttgagt tcctagtcct ccgacaccgc tacaggcatc ccagtaccct gcaactaccc     3600

cacctggggt tctacgtggc caatggctca ggcctcagcc cctcagcccg tggcctgata     3660

gggcagttcc agcacgcaga catccgactg gtgacaggac ctatggggcc atgcttacga     3720

aggcaccatg gcccagatgt gcctgtgatt ctaggcaaga ggctgctgaa ggactcacca     3780

aggctgctgc cccgctgggc ttcctgctgg ctggtgaagc gctctcatgt agagctgctt     3840

ctgggccacc cctacctctc ctatgtcctg                                      3870


<210>  5660
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  5660
cgagcccgcc cagacatgtt ctgccttttc catgggaaga gatactcccc cggcgagagc       60

tggcacccct acttggagcc acaaggcctg atgtactgcc tgcgctgtac ctgctcagag      120

ggcgcccatg tgagttgtta ccgcctccac tgtccgcctg tccactgccc ccagcctgtg      180

acggagccac agcaatgctg tcccaagtgt gtggaacctc acactccctc tggactccgg      240

gccccaccaa agtcctgcca gcacaacggg accatgtacc aacacggaga gatcttcagt      300

gcccatgagc tgttcccctc ccgcctgccc aaccagtgtg tcctctgcag ctgcacagag      360

ggccagatct actgcggcct cacaacctgc cccgaaccag gctgcccagc acccctcccg      420

ctgccagact cctgctgcca ggcctgcaaa gatgaggcaa gtgagcaatc ggatgaagag      480

gacagtgtgc agtcgctcca tggggtgaga catcctcagg atccatgttc cagtgatgct      540

gggagaaaga gaggcccggg caccccagcc cccactggcc tcagcgcccc tctgagcttc      600

atccctcgcc acttcagacc caagggagca ggcagcacaa ctgtcaagat cgtcctgaag      660

gagaaacata agaaagcctg tgtgcatggc gggaagacgt actcccacgg ggaggtgtgg      720

cacccggcct tccgtgcctt cggccccttg ccctgcatcc tatgcacctg tgaggatggc      780

cgccaggact gccagcgtgt gacctgtccc accgagtacc cctgccgtca ccccgagaaa      840

gtggctggga agtgctgcaa gatttgccca gaggacaaag cagaccctgg ccacagtgag      900

atcagttcta ccaggtgtcc caaggcaccg ggccgggtcc tcgtccacac atcggtatcc      960

ccaagcccag acaacctgcg tcgctttgcc ctggaacacg aggcctcgga cttggtggag     1020

atctacctct ggaagctggt aaaagatgag gaaactgagg ctcagagagg tgaagtacct     1080

ggcccaaggc cacacagcca gaatcttcca cttgactcag atcaagaaag tcaggaagca     1140

agacttccag aaagaggcac agcacttccg actgctcgct ggcccccacg aaggtcactg     1200

gaacgtcttc ctagcccaga ccctggagct gaaggtcacg gccagtccag acaaagtgac     1260

caagacata                                                             1269


<210>  5661
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5661
tttaaaaatg atgccacaga aatcctttat tcacatgtgg ttaaacctgt tccagcacac       60

cccagcagca acagcacgtt gaatcaagcc agaaatggag gcaggcattt cagtaacact      120

ggactggatc ggaacactcg ggttcaagtg ggttgccggg aactgcgttc caccaaatac      180

atctctgatg gccagtgcac cagcatcagc cctctgaagg agctggtgtg tgctggcgag      240

tgcttgcccc tgccagtgct ccctaactgg attggaggag gctatggaac aaagtactgg      300

agcaggagga gctcccagga gtggcggtgt gtcaatgaca aaacccgtac ccagagaatc      360

cagctgcagt gccaagatgg cagcacacgc acctacaaaa tcacagtagt cactgcctgc      420

aagtgcaaga ggtacacccg gcagcacaac gagtccagtc acaactttga gagcatgtca      480

cctgccaagc cagtccagca tcacagagag cggaaaagag ccagcaaatc cagcaagcac      540

agcatgagt                                                              549


<210>  5662
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  5662
cttgtctgcc cagctgttgc ttctgagatc acagtcttct tattcttaag tgacgctgcg       60

gtaaacctcc aagttgccaa acttaatcca cctccagaag ctcttgcagc caagttggaa      120

gtgaagcact gcaccgatca gatatctttt aagaaacgac tctcattgaa aaagtcctgg      180

tggaaa                                                                 186


<210>  5663
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  5663
gataataaaa gaccatgcct tgaattctct cagctaagtg taaaggattc cttcagagat       60

ttatttattc cgagaataga gaccattctg atgatgtata caaggaacaa cctaaactgt      120

gctgagccac tgtttgaaca aaataactca cttaatgtta atttcaacac acaaaagaaa      180

acagtctggc ttattcacgg atacagacca gtaggctcca tcccattatg gcttcagaac      240

ttcgtaagga ttttgctgaa tgaagaagat atgaatgtaa ttgtagtaga ctggagccgg      300

ggtgctacaa cttttattta taatagagca gttaaaaaca ccagaaaagt tgctgtgagt      360

ttgagtgtgc acattaaaaa tcttttgaag catggtgcat ctcttgacaa ttttcatttc      420

ataggtgtga gcttaggggc tcatatcagt ggatttgttg gaaagatatt tcatggtcaa      480

cttggaagaa taacaggtct tgaccctgct gggccaaggt tctccagaaa accaccatat      540

agcagattag attacacgga tgcaaagttt gtggatgtca tccattctga ctccaatggt      600

ttaggcattc aagagccctt gggacatata gatttttatc caaatggagg aaataaacaa      660

cctggctgtc ctaaatcaat tttctcagga attcaattca ttaaatgcaa ccaccagaga      720

gcagttcact tgttcatggc atctttagaa acaaactgca attttatttc atttccttgt      780

cgttcataca aagattacaa gactagctta tgtgtggact gtgactgttt taaggaaaaa      840

tcatgtcctc ggctgggtta tcaagccaag ctatttaaag gtgttttaaa agaaaggatg      900

gaaggaagac ctcttaggac cactgtgttt ttggatacaa gtggtacata tccattctgt      960

acctattatt ttgttctcag tataattgtt ccagataaaa ctatgatgga tggctcgttt     1020

tcatttaaat tattaaatca gcttggaatg attgaagagc caaggcttta tgaaaagaac     1080

aaaccatttt ataaacttca agaagtcaag attcttgctc aattttataa tgactttgta     1140

aatatttcaa gcattggttt gacatatttc cagagctcaa atctgcagtg ttccacatgc     1200

acatacaaga tccagagact catgttaaaa tcacttacat acccagaaag accaccactt     1260

tgcaggtata atattgtact taaagacaga gaggaagtgt ttcttaatcc aaacacatgt     1320

acaccaaaga acaca                                                      1335


<210>  5664
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  5664
tgggtagggg gctcagtccc caacctgggc cctgctgagc aggagcagaa ccattacctg       60

gcccagctgt ttggcctgta cggcgagaat gggacgctga ctgcaggggg cttggcgcgg      120

cttctccaca gcctggggct aggccgagtt caggggcttc gcctgggaca gcatgggcct      180

ctgactggac gggctgcatc cccagctgca gacaattcca cacacaggcc acagaaccct      240

gagctgagtg tggatgtctg ggcagggatg cctctgggtc cctcagggtg gggtgacctg      300

gaagagtcaa aggcccctca cctaccccgt gggccagccc cctcgggcct ggacctcctt      360

cacaggcttc tgttgctgga ccactcattg gctgaccacc tgaatgagga ttgtctgaac      420

ggctcccagc tgctggtcaa ttttggcttg agccccgctg ctcctctgac ccctcgtcag      480

tttgctctgc tgtgcccagc cctgctttat cagatcgaca gccgcgtctg catcggcgct      540

ccggcccctg cacccccagg ggatctacta tctgcc                                576


<210>  5665
<211>  1137
<212>  DNA
<213>  Homo Sapiens

<400>  5665
cacttcctag tatttgacca aaaaaaggag tactatcatg gctcctttaa aattttagat       60

ccacaaatca ataacaattt cggacaaagc aacacatatc aacttaagga cttacgagag      120

acgaccgaaa atttggtgga tgagatattt atagattcag cctggaagaa aaattatatc      180

aagaaccaag tagtcagact gactccagag gaagatggtg tgaaagtaga tgtcattatg      240

gtgttccagt tcccctctac tgaacaaagg gcagtaagag agaagaaaat ccaaagcatc      300

ttaaatcaga agataaggaa tttaagagcc ttgccaataa atgcctcatc agttcaagtt      360

aatgcaatga gctcatcaac aggggagtta actgtccaag caagttgtgg taaacgagtt      420

gttccattaa acgtcaacag aatagcatct ggagtcattg cacccaaggc ggcctggcct      480

tggcaagctt cccttcagta tgataacatc catcagtgtg gggccacctt gattagtaac      540

acatggcttg tcactgcagc acactgcttc cagaagtata aaaatccaca tcaatggact      600

gttagttttg gaacaaaaat caaccctccc ttaatgaaaa gaaatgtcag aagatttatt      660

atccatgaga agtaccgctc tgcagcaaga gagtacgaca ttgctgttgt gcaggtctct      720

tccagagtca ccttttcgga tgacatacgc cggatttgtt tgccagaagc ctctgcatcc      780

ttccaaccaa atttgactgt ccacatcaca ggatttggag cactttacta tggtggggaa      840

tcccaaaatg atctccgaga agccagagtg aaaatcataa gtgacgatgt ctgcaagcaa      900

ccacaggtgt atggcaatga tataaaacct ggaatgttct gtgccggata tatggaagga      960

atttatgatg cctgcagggg tgattctggg ggacctttag tcacaaggga tctgaaagat     1020

acgtggtatc tcattggaat tgtaagctgg ggagataact gtggtcaaaa ggacaagcct     1080

ggagtctaca cacaagtgac ttattaccga aactggattg cttcaaaaac aggcatc        1137


<210>  5666
<211>  1236
<212>  DNA
<213>  Homo Sapiens

<400>  5666
gctcccagcg ctgccccaga gcaagtccat ctgtcttacc caggtgagcc aggctccatg       60

actgtaactt ggaccacatg ggtcccaacc cgctctgaag tgcaattcgg gttgcagccg      120

tcggggcccc tgcccctccg cgcccagggc accttcgtcc cctttgtgga cgggggcatt      180

ctccggcgga agctctacat acaccgagtc acgcttcgca agctgctgcc aggggttcag      240

tatgtttatc gctgtggcag tgcgcagggc tggagccgtc ggttccgctt cagggccctc      300

aagaatgggg cccactggag tccccgtctg gctgtgtttg gagacctggg ggctgacaac      360

ccgaaggccg tcccccggct gcgcagggac acccagcagg gcatgtatga cgccgttctc      420

catgtgggag actttgccta caacctggat caggacaacg cccgtgttgg ggataggttc      480

atgcggctca ttgaacccgt ggctgccagc ctgccataca tgacatgccc tgggaatcat      540

gaagaacgct acaacttctc taactacaag gctcgcttca gcatgccggg ggataatgag      600

ggcctgtggt acagctggga tctgggtccc gcccacatca tctccttctc caccgaggtc      660

tatttctttc tccattatgg ccgccacttg gtacagaggc agtttcgctg gctggagagc      720

gacctccaga aagccaataa gaaccgggca gcccggccgt ggatcatcac tatggggcac      780

cggcccatgt actgctccaa cgcagatctg gacgactgca cacgacatga aagcaaggtc      840

cgcaaaggcc tccaaggcaa gctgtacggg ttggaggatc ttttctacaa atatggagtg      900

gatctgcagc tgtgggctca tgagcactcg tatgaacgac tgtggccaat ttacaactac      960

caggtattta acggcagccg agagatgccc tacaccaacc cgcgagggcc tgtccacatc     1020

atcacaggat ctgctggctg tgaggagcgg ctgacgccct ttgctgtctt cccgaggccc     1080

tggagtgccg tgcgtgtgaa ggagtacggg tatacgcggc tgcacatcct caacgggacc     1140

cacatccaca tccagcaggt gtcggacgac caggatggga agatcgtaga tgatgtctgg     1200

gtggtgagac ccctgtttgg ccggaggatg tacctc                               1236


<210>  5667
<211>  264
<212>  DNA
<213>  Homo Sapiens

<400>  5667
tcggattatt ggcttcttgc aactgaagtg gggagatgtt caggtgaaaa gaatatagag       60

aacgtcactt ttcaccatga agggttcttc tggaggtgtt ggtttaatgg gattgtggaa      120

gagaatgact ccaatatttg gaagttctgg tacaccaatc agccaccgtc caagaactgc      180

acacatgctt acctgtctcc gtaccccttc atgagaggcg agcacaactc gacctcctat      240

gactctgcag ttatttaccg tggt                                             264


<210>  5668
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  5668
atgtatgcca aatgtgaaaa tgagccattt gctggtgtat ctgaatcata taatgggact       60

ggagaattgg gaaacttgat agccccttgt aatgccaatt gtaactgttc gcgatcatat      120

tattatcctg tctgtggaga tggagtccaa tatttttctc cctgctttgc aggctgttca      180

aacccagttg cacacaggaa gccaaaggta tattacaact gttcctgtat tgaaaggaaa      240

acagaaataa catccactgc agaaactttt ggttttgaag ctaaagctgg aaaatgtgaa      300

actcattgtg cgaaactgcc catattc                                          327


<210>  5669
<211>  2082
<212>  DNA
<213>  Homo Sapiens

<400>  5669
ctacacctaa tcctcttacc tgctacaggc aatgtggcag agaattctcc acctgggact       60

tcagtgcaca agttttctgt gaagttatca gcatcattgt cacctgtgat cccaggattt      120

ccccagatag tcaactcaaa tcccctcact gaagctttta gggtgaattg gctgtcaggc      180

acctactttg aggttgtcac cactgggatg gaacaactag attttgaaac aggaccaaac      240

atatttgatt tgcagattta tgtgaaggat gaggttggtg tcacagacct tcaagtcctg      300

actgtccagg taacagatgt gaacgagcca cctcagtttc aaggcaactt ggcagaaggt      360

ctacacctct acatagtaga aagagcaaac cctggattca tttaccaggt tgaggccttc      420

gatccagaag acacaagccg aaacattccc ctcagttatt tcctgatttc tcccccaaag      480

agcttcagaa tgtctgctaa tggcaccctc ttctccacaa cagaattgga ctttgaagca      540

ggacacagaa gtttccatct catcgtggag gtgagggaca gtggaggcct caaagcctcc      600

acagagctcc aggtgaacat cgtgaacctc aacgacgaag tccctcgctt taccagcccg      660

acacgagtgt acacagtcct ggaggaactg agtccaggaa ccatcgtggc caatatcaca      720

gcggaggatc ctgatgatga aggttttccc agccacctcc tctacagcat taccactgtt      780

agcaaatatt tcatgataaa tcagttgact ggtacaatcc aagtggccca aaggatagac      840

cgagatgcag gtgaattgag acaaaatccc accatttccc tggaagttct agtgaaggac      900

agaccatatg ggggtcagga gaatcgcatc cagataacct tcattgtgga agacgtcaac      960

gacaatcctg ccacatgcca aaagttcacc ttcagcatta tggtgccgga aagaacagcc     1020

aaggggacgt tgcttcttga cctaaacaag ttctgctttg atgatgacag tgaggcacca     1080

aacaacagat tcaacttcac catgccatct ggagtgggga gcggcagcag atttttacag     1140

gatccagctg gctctgggaa gattgtgctg attggtgatc tagactacga aaatccaagt     1200

aacctagcag ccggcaataa atatacggtg ataatccagg tgcaggatgt ggccccccct     1260

tactataaaa ataacgtcta cgtttatatc ctaacaagcc cagaaaatga gtttcctctc     1320

atttttgata ggccatccta tgtatttgat gtgtcagaaa gaaggcccgc cagaacccga     1380

gtgggacagg tgcgagccac tgataaagac ctcccccaga gcagcctcct gtactccatc     1440

tccactggag gggccagcct ccagtatcca aatgtatttt ggattaatcc caagacagga     1500

gaactccagc tggtaactaa agtggactgt gaaacaaccc ccatctatat tctcagaatc     1560

caggccacca acaacgaaga cacaagctct gtcactgtta ctgtgaacat ccttgaagaa     1620

aatgatgaaa agccaatttg tactccaaac tcttatttcc tggccctccc agtggatctg     1680

aaagttggca caaatattca gaatttcaag ctgacatgta ccgaccttga ttccagcccc     1740

agatctttcc gttattccat tggcccaggt aacgtcaaca atcatttcac cttctctccc     1800

aatgctggtt ccaatgtcac acgcctgctg cttacatctc gctttgacta tgctggtggg     1860

tttgataaga tctgggacta caagctactt gtctacgtaa ctgatgacaa cttgatgtct     1920

gacaggaaga aagcggaggc tcttgttgag acaggaacag tgacactgag tattaaagtc     1980

attccccacc caaccactat catcaccacg acccccaggc ccagggtcac ctatcaggtc     2040

ctgaggaaaa acgtttactc tccatctgca tggtacgtgc cg                        2082


<210>  5670
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  5670
aaagggaagt tcgtaggcta tcctggaaaa tacacatatt tatttaatga gtggagaagt       60

gaagagtgtg atcctggagg ctgtcttata gaattgacaa cccaattgac cattataatg      120

accgggaaac agatttttgg aaacattaaa gaagccattt atcccttggc tttgaattgg      180

tggagacgcc gaaaagctcg gacaaactct gagaagctgt atagtcgatg ggagcaggat      240

catgaccttg aaagttttgg accccttggg cttttctatg agtacttaga aacagttact      300

caa                                                                    303


<210>  5671
<211>  2199
<212>  DNA
<213>  Homo Sapiens

<400>  5671
gctgtttcgg atcagcatgc cacaagcccc ttcgactggc tcctctctga taagggaccc       60

ttccatcgct cacaggaata cacagatttt gtggacagaa gccggcaggg atttagcaca      120

agatacaaga tatacaggga gtttggccgc tggaaagtaa ataaccttgc agttgagaga      180

agaaatttcc ttggctctcc tctgcctctt gcccctgaat tcttccgcaa cataagactt      240

ttgggacgtc gacctaccct tcagcaaatc acagaaaacc ttatcaagaa atatgggaca      300

catttcttgc tatctgctac tctgggagga gaggagtcac tcacaatttt tgtggacaag      360

cggaagttga gcaaacgagc tgaaggaagt gattccacca ccaatagctc ttcggtcact      420

ctggagacgc tacatcagct agccgcttct tatttcattg acagggacag cacccttcgg      480

agacttcacc acattcaaat tgcatccact gccataaagg taacagaaac acggactggt      540

cctcttggct gcagtaacta tgacaaccta gattctgtca gttctgttct ggttcagagt      600

cctgagaata agattcagtt gcaagggctt caagtacttc tcccagacta tcttcaggaa      660

cgttttgtac aagcagcttt gagctacatt gcttgcaatt cagagggaga gtttatctgc      720

aaggaaaatg actgctggtg tcactgtggt cccaaatttc cagaatgcaa ctgcccctcc      780

atggacattc aagccatgga agagaatctt cttcgaataa ctgaaacctg gaaagcttac      840

aacagtgact ttgaggaatc agatgaattc aagttattta tgaaaaggct acctatgaat      900

tatttcctca acacatctac tataatgcat ttgtggacaa tggattctaa ttttcagcgc      960

cgttatgaac aactggagaa cagcatgaaa caacttttcc taaaggcgca gaaaattgta     1020

cacaagcttt ttagccttag caagaggtgt cataaacaac ccctcatcag cctgccaaga     1080

caaagaacct caacctactg gcttactcgc atccagtctt ttctctactg caatgagaac     1140

ggcctcctag gcagcttttc agaagagacg cactcgtgca cgtgtccgaa tgaccaggtg     1200

gtctgcaccg cgttcctgcc ctgcacagtg ggagacgcct ctgcctgcct gacatgcgca     1260

ccagacaacc gcacccgctg cggcacctgc aacaccggct acatgctcag ccaggggctc     1320

tgcaagcctg aagtcgccga gtccaccgat cactatattg gctttgaaac tgacctgcaa     1380

gatctcgaga tgaaatatct gctgcagaaa acggacagac gaatagaagt ccatgccatt     1440

tttatcagca atgacatgcg cctcaatagc tggtttgatc cctcctggcg taagcggatg     1500

ctcctcacct tgaagagcaa taagtacaag tcaagtctgg tccatatgat tttgggtctc     1560

tctttacaga tttgcttaac taaaaacagc accttggagc cagtgttggc tgtttatgtc     1620

aatcccttcg gaggcagcca ctctgagagc tggtttatgc ctgtgaatga aaacagcttt     1680

ccagactggg agcggactaa gttggaccta cccctgcagt gttataactg gacattaact     1740

ctggggaaca aatggaagac attttttgag acagtacaca tctacctgag aagtcgcatc     1800

aagtccaatg gtcccaatgg taatgagagc atttactatg aacctctgga gtttattgac     1860

ccttcccgga acctgggcta tatgaaaatc aataacattc aagtgtttgg ctacagcatg     1920

cactttgacc ctgaagcaat tcgggacctg attttgcagc tggactaccc ctatactcag     1980

ggatcccagg attcagcact tttgcaacta ctagagatca gagaccgtgt aaataaactc     2040

tccccacctg gtcagcgtcg tctagatctt ttctcttgct tgcttcgtca tagactcaag     2100

ctgtctacta gtgaggtggt gaggatccaa tctgctctgc aggcgtttaa tgccaaattg     2160

ccaaacacaa tggattatga cacgaccaaa ttatgtagt                            2199


<210>  5672
<211>  390
<212>  DNA
<213>  Homo Sapiens

<400>  5672
cctgacatga tccgccatct ccaggcagtg gactacgcat cccgcaccaa agtgttcccc       60

ggggagcgcg tagagcatgt aacttttaac ttcacgttgg agaatcagat ccaccgaggc      120

gggcagtact tcaatgacaa gttcattggg ctgcggctca agtcagtgtc ctttgaggat      180

tccctgtttg aagagtgtta ttttgaggat gtcacatcca gcaacacgtt tttccgcaac      240

tgcacattca tcaacactgt gttctataac actgacctgt tcgagtacaa gtttgtgaac      300

agccgtctga taaacagtac attcctgcac aacaaggagg gctgcccgct agacgtgaca      360

gggacgggcg aaggtgccta catggtatac                                       390


<210>  5673
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  5673
cctgatatga tccgctattt tcaagatgaa gaatacaagt ctaaaatgaa ggtgtttttt       60

ggtgagcatg tgtacggcgc cacaatcaac ttcacgatgg aaaatcagat ccaccaacat      120

gggaaacttg tgaatgataa gttcacaaga atgtacttta aacatgtact ctttgaggac      180

acattctttg acgagtgcta ttttgaagac gtaacatcaa cagataccta cttcaaaaat      240

tgtaccattg aatcaaccat cttttacaac acagacctct acgagcacaa gttcatcaac      300

tgtcggttta tcaactccac cttcctggag cagaaggagg gctgccacat ggacttggag      360

caagataatg ac                                                          372


<210>  5674
<211>  1095
<212>  DNA
<213>  Homo Sapiens

<400>  5674
atgccagggg ggaagaaggt ggctgggggt ggcagcagcg gtgccactcc aacgtccgct       60

gcggccaccg ccccctctgg ggtcaggcgt ttggagacca gcgaaggaac ctcagcccag      120

agagatgagg agccagaaga ggaaggggaa gaggacctgc gagacggagg cgtccccttc      180

tttgtcaacc ggggtgggct acctgtggat gaggccacct gggaaaggat gtggaaacac      240

gtggccaaga tccaccccga tggagagaag gtggcgcaac ggatccgtgg ggccacagac      300

ctgcccaaga tccccatacc gagtgtgcct acgttccagc cgtctacacc tgtccctgag      360

cgcctggaag ctgtgcagcg ctacatcaga gagctgcagt acaatcacac agggacacag      420

ttctttgaaa ttaagaagag cagacctctg acagggctga tggacctggc caaggaaatg      480

accaaagagg ccctgccaat caaatgcctg gaagccgtga tcctgggaat ttacctcacc      540

aacagcatgc ccaccctgga gcgcttcccc atcagcttca agacctactt ctcagggaac      600

tacttccgcc acatcgtgct gggggtgaac ttcgcgggcc gctacggtgc gctgggcatg      660

agtcggcgcg aggacctgat gtacaagccg cccgccttcc gcacgctcag cgagctcgtg      720

ctggacttcg aggccgccta cggccgctgc tggcacgtgc tcaagaaggt gaagctgggc      780

cagagcgtgt cacacgaccc gcacagcgtg gagcagatcg agtggaagca ctcggtgctg      840

gacgtggagc gcctgggccg cgatgacttc cgcaaggagc tggagcgcca cgcccgcgac      900

atgcggctca agattggcaa agggacgggc cctccctctc ccaccaagga ccggaagaag      960

gatgtttctt ccccgcagcg ggcccagtcc agcccccacc gcaggaacag ccgcagtgaa     1020

agacggccct cgggtgacaa gaagacttcc gagcccaaag ccatgccaga ccttaacggg     1080

taccagatcc gggtc                                                      1095


<210>  5675
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  5675
atgggctccg tggggagcca gcgccttgag gagcccagcg tggcaggcac accagacccg       60

ggcgtagtga tgagcttcac cttcgacagt caccagctgg aggaggcggc ggaggcggct      120

cagggccagg gccttagggc caggggcgtc ccagctttca cggatactac attggacgag      180

ccagtgcccg atgaccgtta tcac                                             204


<210>  5676
<211>  3282
<212>  DNA
<213>  Homo Sapiens

<400>  5676
tatacagtgc caaattccag gcaggatttg catccattgt tgcaaaacat ggcggaagaa       60

ataatagatg gaagctatct gaatgcactg ctggatctca tacagtttca aagctcccac      120

gtgtggacgg atgacctgtc ccacagagtc ctggcctatc tgaattcccg gaatgttgcc      180

ttcaccatcc ccagcctgca ggcagccgtg gaaaaccacc tggagcagcg tctgcaccag      240

ccccagaagc tgctggagga cctgaggaag acagacgccc agcagttccg cactgccatg      300

aaatgcctct tagaagacaa gaaggacggc ttggacctga aagacatcat catcgactta      360

ggagagattc gagaacgagc cttgcagagc cctggcgtga accgcagcct gtttctcatc      420

acactggaga ggtgtttcca gatgctgaac tccctggagt gtgtggagat cctgggcaag      480

gtgctgaggg ggtcctcagg gagctttctc cagccagaca tcacagagcg gctccctcgg      540

gacctgcgcg aggatgcctt taagaaccta tctgcagtgt tcaaagatct ctacgacaaa      600

acctcggctc attcccagag agctctctat tcctggatga ctggaatact gcagacatcc      660

tccaatgcca ctgatgactc tgcttcatgg gtcagtgcgg aacacttatg ggttttgggc      720

agatacatgg ttcacctatc gtttgaagaa attacgaaaa ttagtcctat agaaattggg      780

ctgtttatca gctatgacaa cgccaccaag cagctggaca tggtctatga catcacacct      840

gagctggccc aggcgtttct ggagaggatc agctcctcca actttaacat gaggaatacc      900

tccaccatcc acaggctggg gctgctggtt tgtttctaca atgacctgga attgctggat      960

gccactgtgg ctcaagtcct gctttaccag atgatcaagt gcagccacct gaggggcttc     1020

caggctggcg tccagaagct caaagcagaa ctcctggaca ttgccatgga gaaccagacc     1080

ctcaatgaga ccctgggttc tttgtcggat gcagttgtag gtttgaccta cagccaactg     1140

gaatccctct cccccgaggc tgtgcacgga gccatctcca ccctcaacca ggtctcaggt     1200

tgggccaaga gccaggtcat catcttgtct gccaaatact tggcccatga gaaggtgctg     1260

tctttctaca atgtcagcca gatgggcgca ctgctggctg gggtcagcac ccaggccttc     1320

tgcagcatga aacgcaagga catctcgcag gtcctgagaa gtgccgtctc ccagtatgta     1380

tccgacttgt cacctgccca gcagcaaggt atcctcagca agatggtcca agcggaagac     1440

actgccccag gcatcgtgga gatacaaggg gctttcttta aggaagtgtc tctctttgat     1500

ttaaggaggc aacctggatt caactctaca gtcctgaagg ataaggaact tggaaggagc     1560

caggctctgt tcctgtatga gcttctgtta aagaccacca gaaggcctga ggagcttttg     1620

agtgctgggc agctggtcaa aggcgtgacc tgctcacaca ttgatgccat gagcactgac     1680

ttctttctgg cccatttcca ggattttcag aacaacttcg ccctgctttc accctatcag     1740

gttaattgtt tggcgtggaa atactgggaa gtttccagat tgtctatgcc acctttcctc     1800

ttggctgcac tcccggcccg ctacctggct tctgtcccag cctcccagtg tgtgcccttt     1860

ctgatcagcc tggggaagag ctggttggac tccttggttt tagattccca caaaaagact     1920

tcagtcctca ggaaagtgca gcagtgcctg gacgactcca ttgctgatga gtacactgtg     1980

gacatcatgg ggaacctgct gtgtcacttg ccggcagcca tcatcgacag ggggatctcc     2040

cccagggctt gggcgactgc tctacacggc ctcagagact gcccagacct caaccctgag     2100

caaaaggctg cagtgaggct caagctcctg ggacagtatg gactccctca gcactggaca     2160

gccgagacca cgaaggactt gggacccttt ctagtacttt tctcaggaga tgaattaagc     2220

tctatagcca caaagtttcc tgagatcctt ctgcaagcag cttccaagat ggccaggacc     2280

ctgcccacta aagaattcct ctgggctgtc tttcagtctg ttcggaacag cagtgataag     2340

atccccagct atgaccctat gcctggttgc catggagtcg tggccccctc ttctgatgac     2400

atcttcaagt tggccgaagc caacgcctgc tgggccctgg aggacctgcg gtgcatggag     2460

gaagacacat tcatcaggac cgtggaactg ctgggagctg tccagggttt cagccggcct     2520

cagctgatga ccctgaagga gaaagcaata caggtttggg acatgccatc ttactggaga     2580

gaacaccata tcgtctccct ggggcgcatt gctctggctc ttaatgagag tgagctggag     2640

cagctggacc tcagctccat agacactgtg gcttccctaa gctggcaaac agaatggacc     2700

ccgggacagg ctgaatccat tttgcaaggg tacctggatg attcaggata cagtatccag     2760

gacctgaaga gctttcattt ggtaggactt ggtgcaaccc tgtgtgctat aaacatcact     2820

gaaatcccac ttataaagat ctcagaattc agggtggtag tggccagaat tgggaccctg     2880

ctctgcagca cacatgtctt agccgagttt aagaggaagg ctgaagttgt gtttggggat     2940

cccactgagt ggaccagttc tgtcttgcag gagcttggga ccattgcagc tggattaact     3000

aaggcagcgc tccggatgct tgacaaggat ttgatgccat atttccagcc atcagcaata     3060

aaatgccttc ctgatgagat attcaaagag ctgtccgcgg agcagatcgc ctccctgggt     3120

ccggagaacg ccgcggcggt gacccacgcc cagcgccggc ggctcagtcc actgcagctg     3180

cagagcctcc agcaggcgct agatggcgcc aagactcact cctggcagga cgcgcccgct     3240

agcgccggtc ccactagaac ctcatcctcg cgttctcccg ca                        3282


<210>  5677
<211>  1650
<212>  DNA
<213>  Homo Sapiens

<400>  5677
gccccattgt gcctgtcaca gcaacttagg atgaaggggg actacgtgct gggggggctg       60

ttccccctgg gcgaggccga ggaggctggc ctccgcagcc ggacacggcc cagcagccct      120

gtgtgcacca ggttctcctc aaacggcctg ctctgggcac tggccatgaa aatggccgtg      180

gaggagatca acaacaagtc ggatctgctg cccgggctgc gcctgggcta cgacctcttt      240

gatacgtgct cggagcctgt ggtggccatg aagcccagcc tcatgttcct ggccaaggca      300

ggcagccgcg acatcgccgc ctactgcaac tacacgcagt accagccccg tgtgctggct      360

gtcatcgggc cccactcgtc agagctcgcc atggtcaccg gcaagttctt cagcttcttc      420

ctcatgcccc aggtcagcta cggtgctagc atggagctgc tgagcgcccg ggagaccttc      480

ccctccttct tccgcaccgt gcccagcgac cgtgtgcagc tgacggccgc cgcggagctg      540

ctgcaggagt tcggctggaa ctgggtggcc gccctgggca gcgacgacga gtacggccgg      600

cagggcctga gcatcttctc ggccctggcc gcggcacgcg gcatctgcat cgcgcacgag      660

ggcctggtgc cgctgccccg tgccgatgac tcgcggctgg ggaaggtgca ggacgtcctg      720

caccaggtga accagagcag cgtgcaggtg gtgctgctgt tcgcctccgt gcacgccgcc      780

cacgccctct tcaactacag catcagcagc aggctctcgc ccaaggtgtg ggtggccagc      840

gaggcctggc tgacctctga cctggtcatg gggctgcccg gcatggccca gatgggcacg      900

gtgcttggct tcctccagag gggtgcccag ctgcacgagt tcccccagta cgtgaagacg      960

cacctggccc tggccaccga cccggccttc tgctctgccc tgggcgagag ggagcagggt     1020

ctggaggagg acgtggtggg ccagcgctgc ccgcagtgtg actgcatcac gctgcagaac     1080

gtgagcgcag ggctaaatca ccaccagacg ttctctgtct acgcagctgt gtatagcgtg     1140

gcccaggccc tgcacaacac tcttcagtgc aacgcctcag gctgccccgc gcaggacccc     1200

gtgaagccct ggcagctcct ggagaacatg tacaacctga ccttccacgt gggcgggctg     1260

ccgctgcggt tcgacagcag cggaaacgtg gacatggagt acgacctgaa gctgtgggtg     1320

tggcagggct cagtgcccag gctccacgac gtgggcaggt tcaacggcag cctcaggaca     1380

gagcgcctga agatccgctg gcacacgtct gacaaccaga agcccgtgtc ccggtgctcg     1440

cggcagtgcc aggagggcca ggtgcgccgg gtcaaggggt tccactcctg ctgctacgac     1500

tgtgtggact gcgaggcggg cagctaccgg caaaacccag acgacatcgc ctgcaccttt     1560

tgtggccagg atgagtggtc cccggagcga agcacacgct gcttccgccg caggtctcgg     1620

ttcctggcat ggggcgagcc ggctgtgctg                                      1650


<210>  5678
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  5678
caacctgtat actccagccg cgttgtaggt ggccaggatg ctgctgcagg gcgctggcct       60

tggcaggtca gcctacactt tgaccacaac tttatctatg gaggttccct cgtcagtgag      120

aggttgatac tgacagcagc acactgcata caaccgacct ggactacttt ttcatatact      180

gtgtggctag gatcgattac agtaggtgac tcaaggaaac gtgtgaagta ctacgtgtcc      240

aaaatcgtca tccatcccaa gtaccaagat acaacggcag acgtcgcctt gttgaaactg      300

tcctctcaag tcaccttcac ttctgccatc ctgcctattt gcttgcccag tgtcacaaag      360

cagttggcaa ttccaccctt ttgttgggtg accggatggg gaaaagttaa ggaaagttca      420

gatagagatt accattctgc ccttcaggaa gcagaagtac ccattattga ccgccaggct      480

tgtgaacagc tctacaatcc catcggtatc ttcttgccag cactggagcc agtcatcaag      540

gaagacaaga tttgtgctgg tgatactcaa aacatgaagg atagttgcaa gggtgattct      600

ggagggcctc tgtcgtgtca cattgatggt gtatggatcc agacaggagt agtaagctgg      660

ggattagaat gtggtaaatc tcttcctgga gtctacacca atgtaatcta ctaccaaaaa      720

tggattaatg ccactatttc aagagccaac aatctagact tctctgactt cttgttccct      780

attgtcctac tctctctggc tctcctgtgt ccctcctgtg cctttggacc taacactata      840

cacagagtag gcactgtagc tgaagctgtt gcttgcatac agggctggga agagaatgca      900

tggagattta gtcccagggg caga                                             924


<210>  5679
<211>  3264
<212>  DNA
<213>  Homo Sapiens

<400>  5679
attagtagtt ggagaaattc aacagtgact ggacatccat ggcaggtctc cctaaaatca       60

gatgagcacc acttctgtgg aggaagcttg attcaagaag atcgggttgt tacagcagca      120

cactgcctgg acagcctcag tgagaagcag ctgaagaata taactgtgac ttctggggag      180

tacagcctct ttcagaagga taagcaagaa cagaatattc ctgtctcaaa aattattacc      240

catcctgaat acaacagccg tgaatatatg agtcctgata ttgcactgct gtatctaaaa      300

cacaaagtca agtttggaaa tgctgttcag ccaatctgtc ttcctgacag cgatgataaa      360

gttgaaccag gaattctttg cttatccagt ggatggggca agatttccaa aacatcagaa      420

tattcaaatg tcctacaaga aatggaactt cccatcatgg atgacagagc gtgtaatact      480

gtgctcaaga gcatgaacct ccctcccctg ggaaggacca tgctgtgtgc tggcttccct      540

gattggggaa tggacgcctg ccagggggac tctggaggac cactggtttg tagaagaggt      600

ggtggaatct ggattcttgc tgggataact tcctgggtag ctggttgtgc tggaggttca      660

gttcccgtaa gaaacaacca tgtgaaggca tcacttggca ttttctccaa agtgtctgag      720

ttgatggatt ttatcactca aaacctgttc acaggtttgg atcggggcca acccctctca      780

aaagtgggct caaggtatat aacaaaggcc ctgagttctg tccaagaagt gaatggaagc      840

cagagaggaa agggtatttt agacatggaa aagcaagttg gatgtgatca tgactatgta      900

tctttacgat caagcagtgg agtgcttttt aatcagagat ctctcatgga agacgatgga      960

aaacaaaaca aacgtgtctg tggaaaaata ttgccttcac cattgctggc agagaccagt     1020

gaggccatgg ttccatttgt ttctgataca gaagacagtg gcagtggctt tgagcttacc     1080

gttactgctg tacagaagtc agaagcaggg tcaggttgtg ggagtctggc tatattggta     1140

gaagaaggga caaatcactc tgccaagtat cctgatttgt atcccagtaa cacaaggtgt     1200

cattggttca tttgtgctcc agagaagcac attataaagt tgacatttga ggactttgct     1260

gtcaaattta gtccaaactg tatttatgat gctgttgtga tttacggtga ttctgaagaa     1320

aagcacaagt tagctaaact ttgtggaatg ttgaccatca cttcaatatt cagttctagt     1380

aacatgacgg tgatatactt taaaagtgat ggtaaaaatc gtttacaagg cttcaaggcc     1440

agatttacca ttttgccctc agagtcttta aacaaatttg aaccaaagtt acctccccaa     1500

aacaatcctg tatctaccgt aaaagctatt ctgcatgatg tctgtggcat ccctccattt     1560

agtccccagt ggctttccag aagaatcgca ggaggggaag aagcctgccc ccactgttgg     1620

ccatggcagg tgggtctgag gtttctaggc gattaccaat gtggaggtgc catcatcaac     1680

ccagtgtgga ttctgaccgc agcccactgt gtgcaattga agaataatcc actctcctgg     1740

actattattg ctggggacca tgacagaaac ctgaaggaat caacagagca ggtgagaagg     1800

gccaaacaca taatagtgca tgaagacttt aacacactaa gttatgactc tgacattgcc     1860

ctaatacaac taagctctcc tctggagtac aactcggtgg tgaggccagt atgtctccca     1920

cacagcgcag agcctctatt ttcctcggag atctgtgctg tgaccggatg gggaagcatc     1980

agtgcagatg gtggcctagc aagtcgccta cagcagattc aagtgcatgt gttagaaaga     2040

gaggtctgtg aacacactta ctattctgcc catccaggag ggatcacaga gaagatgatc     2100

tgtgctggct ttgcagcatc tggagagaaa gatttctgcc agggagactc tggtgggcca     2160

ctagtatgta gacatgaaaa tggtcccttt gtcctctatg gcattgtcag ctggggagct     2220

ggctgtgtcc agccatggaa gccgggtgta tttgccagag tgatgatctt cttggactgg     2280

atccaatcaa aaatcaatgg tcctgcttca cttcagacaa ataataaatg caaaacctta     2340

aaacaacaat tgccaccacc cacaccttca ccagacagtg catcttggcc aggttgttgc     2400

tctgaagcag agctagaaaa gcctagaggc ttttttccca caccacggta tctactggat     2460

tatagaggaa gactggaatg ttcttgggtg ctcagagttt cagcaagcag tatggcaaaa     2520

tttaccattg agtatctgtc actcctgggg tctcctgtgt gtcaagactc agttctaatt     2580

atttatgaag aaagacacag taagagaaag acggcaggtg gattacatgg aagaagactt     2640

tactcaatga ctttcatgag tcctggaccg ctggtgaggg tgacattcca tgcccttgta     2700

cgaggtgcat ttggtataag ctatattgtc ttgaaagtcc taggtccaaa ggacagtaaa     2760

ataaccagac tttcccaaag ttcaaacaga gagcacttgg tcccttgtga ggatgttctt     2820

ctgaccaagc cagaagggat catgcagatc ccaagaaatt ctcacagaac tactatgggt     2880

tgccaatgga gattagtagc ccctttaaat cacatcattc agcttaatat tattaacttc     2940

ccgatgaagc caacaacttt tgtctgtcat ggtcatctgc gtgtttacga aggatttgga     3000

ccaggaaaaa aattaatagc ttcattcgct ggaactctgg caatgatact gacaaaagac     3060

atattaaaaa gagaaaaact gaattttatt aacacatata tcatgcatat atgggaaaat     3120

tcagtgtatg ataatgtaag aagtgttgga aaaagaaaac agaagaaatt tgcatcaaat     3180

ttaagttata gtatggaggc tgagaagtcc aggatccagg tgccagcaga tttggtgcct     3240

gctaagggct cactttctgg ttct                                            3264


<210>  5680
<211>  2004
<212>  DNA
<213>  Homo Sapiens

<400>  5680
ctcgacctgc ccgctgggtc ctgtgccttt gaagagagca cttgcggctt tgactccgtg       60

ttggcctctc tgccgtggat tttaaatgag gaaggccatt acatttatgt ggatacctcc      120

tttggcaagc agggggagaa agctgtgctg ctaagtcctg acttacaggc tgaggaatgg      180

agctgcctcc gtttggtcta ccagataacc acatcttcgg agtctctgtc agatcccagc      240

cagctgaacc tctacatgag atttgaagat gaaagctttg atcgcttgct ttggtcagct      300

aaggaacctt cagacagctg gctcatagcc agcttggatt tgcaaaacag ttccaagaaa      360

ttcaagattt taatagaagg tgtactagga cagggaaaca cagccagcat cgcactattt      420

gaaatcaaga tgacaaccgg ctactgtatt gaatgtgact ttgaagaaaa tcatctctgt      480

ggctttgtga accgctggaa tcccaatgtg aactggtttg ttggaggagg aagtattcgg      540

aatgtccact ccattctccc acaggatcac accttcaaga gtgaactggg ccactacatg      600

tacgtggact cagtttatgt gaagcacttc caggaggtgg cacagctcat ctccccgttg      660

accacggccc ccatggctgg ctgcctgtca ttttattacc agatccagca ggggaatgac      720

aatgtctttt ccctttacac tcgggatgtg gctggccttt acgaggaaat ctggaaagca      780

gacaggccag ggaatgctgc ctggaacctt gcggaggtcg agttcaatgc tccttacccc      840

atggaggtta tttttgaagt tgctttcaat ggtcccaagg gaggttatgt tgccctggat      900

gatatttcat tctctcctgt tcactgccag aatcagacag aacttctgtt cagtgccgtg      960

gaagccagct gcaattttga gcaagatctc tgcaactttt accaagataa agaaggtcca     1020

ggttggaccc gagtgaaagt aaaaccaaac atgtatcggg ctggagacca cactacaggc     1080

ttagggtatt acctgctagc caacacaaag ttcacatctc agcctggcta cattggaagg     1140

ctctatgggc cctccctacc aggaaacttg cagtattgtc tgcgttttca ttatgccatc     1200

tatggatttt taaaaatgag tgacacccta gcagtttaca tctttgaaga gaaccatgtg     1260

gttcaagaga agatctggtc tgtgttggag tccccaaggg gtgtttggat gcaagctgaa     1320

atcaccttta agaagcccat gcctaccaag gtggttttca tgagcctatg caaaagtttc     1380

tgggactgtg ggcttgtagc cctggatgac attacaatac aattgggaag ctgctcatct     1440

tcagagaaac ttccacctcc acctggagag tgtactttcg agcaagatga atgtacattt     1500

actcaggaga aaagaaaccg gagcagctgg cacaggagga ggggagaaac tcccacttcc     1560

tacacaggac caaagggaga tcacactact ggggtaggct actacatgta cattgaggcc     1620

tcccatatgg tgtatggaca aaaagcacgc ctcttgtcca ggcctctgcg aggagtctct     1680

ggaaaacact gcttgacctt tttctaccac atgtatggag ggggcactgg cctgctgagt     1740

gtttatctga aaaaggaaga agacagtgaa gagtccctct tatggaggag aagaggtgaa     1800

cagagcattt cctggctacg agcactgatt gaatacagct gtgagaggca acaccagata     1860

atttttgaag ccattcgagg agtatcaata agaagtgata ttgccattga tgatgttaaa     1920

tttcaggcag gaccctgtgg agaaatggaa gatacaactc aacaatcatc aggatattct     1980

gaggacttaa atgaaattga gtat                                            2004


<210>  5681
<211>  651
<212>  DNA
<213>  Homo Sapiens

<400>  5681
atggcaggga ggcatcagaa tcgtagtttt cctcttccag gagttcagtc aagtggtcaa       60

gtacatgcat ttggaaattg ttcagacagt gatattttgg aggaggatgc tgaagtgtat      120

gagcttcgat ccagaggaaa agagaaagtc cgaagaagta catcaagaga tagacttgac      180

gacattatag tattaacaaa agatatacaa gaaggagata cattaaatgc aatagccctt      240

cagtactgtt gtacggtagc agatatcaag agagttaaca atctcatcag tgatcaagac      300

ttttttgccc ttaggtctat caaaattcca gtaaaaaagt tcagttcctt gaccgaaaca      360

ctttgtcctc caaaaggaag acagacttca cgtcattcat ctgttcaata ctcttccgaa      420

caacaggaaa ttttgccagc taatgattct cttgcttaca gtgactcagc tggtagcttt      480

ttaaaagaag tagaccgaga catagaacaa atagtaaagt gtacagacaa taagagagag      540

aacctcaatg aggtagtatc ggccttaaca gcacaacaaa tgcgttttga acctgataac      600

aaaaacactc aacgtaaaga cccctattat ggagcagact ggggaatagg g               651


<210>  5682
<211>  3288
<212>  DNA
<213>  Homo Sapiens

<400>  5682
gcaactccca acttcctcgc aaaccccagc tccagcagcc gctggattcc cctccagcca       60

atgcccgtgg cctgggcctt tgtgcagaag acctcggccc tcctgtggct gctgcttcta      120

ggcacctccc tgtcccctgc gtggggacag gccaagattc ctctggaaac agtgaagcta      180

tgggctgaca ccttcggcgg ggacctgtat aacactgtga ccaaatactc aggctctctc      240

ttgctgcaga agaagtacaa ggatgtggag tccagtctga agatcgagga ggtggatggc      300

ttggagctgg tgaggaagtt ctcagaggac atggagaaca tgctgcggag gaaagtcgag      360

gcggtccaga atctggtgga agctgccgag gaggccgacc tgaaccacga attcaatgaa      420

tccctggtgt tcgactatta caactcggtc ctgatcaacg agagggacga gaagggcaac      480

ttcgtggagc tgggcgccga gttcctcctg gagtccaatg ctcacttcag caacctgccg      540

gtgaacacct ccatcagcag cgtgcagctg cccaccaacg tgtacaacaa agacccagat      600

attttaaatg gagtctacat gtctgaagcc ttgaatgctg tcttcgtgga gaacttccag      660

agagacccaa cgttgacctg gcaatatttt ggcagtgcaa ctggattctt caggatctat      720

ccaggtataa aatggacacc tgatgagaat ggagtcatta cttttgactg ccgaaaccgc      780

ggctggtaca ttcaagctgc tacttctccc aaggacatag tgattttggt ggacgtgagc      840

ggcagtatga aggggctgag gatgactatt gccaagcaca ccatcaccac catcttggac      900

accctggggg agaatgactt cgttaatatc atagcgtaca atgactacgt ccattacatc      960

gagccttgtt ttaaagggat cctcgtccag gcggaccgag acaatcgaga gcatttcaaa     1020

ctgctggtgg aggagttgat ggtcaaaggt gtgggggtcg tggaccaagc cctgagagaa     1080

gccttccaga tcctgaagca gttccaagag gccaagcaag gaagcctctg caaccaggcc     1140

atcatgctca tcagcgacgg cgccgtggag gactacgagc cggtgtttga gaagtataac     1200

tggccagact gtaaggtccg agttttcact tacctcattg ggagagaagt gtcttttgct     1260

gaccgcatga agtggattgc atgcaacaac aaaggctact acacgcagat ctcaacgctg     1320

gcggacaccc aggagaacgt gatggaatac ctgcacgtgc tcagccgccc catggtcatc     1380

aaccacgacc acgacatcat ctggacagag gcctacatgg acagcaagct cctcagctcg     1440

caggctcaga gcctgacact gctcaccact gtggccatgc cagtcttcag caagaagaac     1500

gaaacgcgat cccatggcat tctcctgggt gtggtgggct cagatgtggc cctgagagag     1560

ctgatgaagc tggcgccccg gtacaagctt ggagtgcacg gatacgcctt tctgaacacc     1620

aacaatggct acatcctctc ccatcccgac ctccggcccc tgtacagaga ggggaagaaa     1680

ctaaaaccca aacctaacta caacagtgtg gatctctccg aagtggagtg ggaagaccag     1740

gctgaatctc tgagaacagc catgatcaat agggaaacag gtactctctc gatggatgtg     1800

aaggttccga tggataaagg gaagcgagtt cttttcctga ccaatgacta cttcttcacg     1860

gacatcagcg acaccccttt cagtttgggg gtggtgctgt cccggggcca cggagaatac     1920

atccttctgg ggaacacgtc tgtggaagaa ggcctgcatg acttgcttca cccagacctg     1980

gccctggccg gtgactggat ctactgcatc acagatattg acccagacca ccggaagctc     2040

agccagctag aggccatgat ccgcttcctc gccaggaagg acccagacct ggagtgtgac     2100

gaggagctgg tccgggaggt gctgtttgac gcggtggtga cagcccccat ggaagcctac     2160

tggacagcgc tggccctcaa catgtccgag gagtctgaac acgtggtgga catggccttc     2220

ctgggcaccc gggctggcct cctgagaagc agcttgttcg tgggctccga gaaggtctcc     2280

gacaggaagt tcctgacacc tgaggacgag gccagcgtgt tcaccctgga ccgcttcccg     2340

ctgtggtacc gccaggcctc agagcatcct gctggcagct tcgtcttcaa cctccgctgg     2400

gcagaaggac cagaaagtgc gggtgaaccc atggtggtga cggcaagcac agctgtggcg     2460

gtgaccgtgg acaagaggac agccattgct gcagccgcgg gcgtccaaat gaagctggaa     2520

ttcctccagc gcaaattctg ggcggcaacg cggcagtgca gcactgtgga tgggccgtgc     2580

acacagagct gcgaggacag tgatctggac tgcttcgtca tcgacaacaa cgggttcatt     2640

ctgatctcca agaggtcccg agagacggga agatttctgg gggaggtgga tggtgctgtc     2700

ctgacccagc tgctcagcat gggggtgttc agccaagtga ctatgtatga ctatcaggcc     2760

atgtgcaaac cctcgagtca ccaccacagt gcagcccagc ccctggtcag cccaatttct     2820

gccttcttga cggcgaccag gtggctgctg caggagctgg tgctgttcct gctggagtgg     2880

agtgtctggg gctcctggta cgacagaggg gccgaggcca aaagtgtctt ccatcactcc     2940

cacaaacaca agaagcagga cccgctgcag ccctgcgaca cggagtaccc cgtgttcgtg     3000

taccagccgg ccatccggga ggccaacggg atcgtggagt gcgagccctg ccagaaggta     3060

tttgtggtgc agcagattcc caacagtaac ctcctcctcc tggtgacaga ccccacctgt     3120

gactgcagca tcttcccacc agtgctgcag gaggcgacag aagtcaaata taatgcctct     3180

gtcaaatgtg accggatgcg ctcccagaag ctccgccggc gaccagactc ctgccacgcc     3240

ttccatccag aggagaatgc ccaggactgc ggcggcgcct cggacacc                  3288


<210>  5683
<211>  234
<212>  DNA
<213>  Homo Sapiens

<400>  5683
catcgctcgg tgtctgggct gaagcagaca ctgctggcgg agtccgaggc tctgaccagc       60

tacagccacc gggtgttctc ggcctgggac ttcggtctct gcggggacgt ccacgtgcgg      120

ctgcgccagc gcatcatctt gtacgaatta aaggtggagc tggaggagac agtggtgcgg      180

cgccaggctg cggtgcggac gctgggccag caagccaggg tttggttggt gcgg            234


<210>  5684
<211>  3027
<212>  DNA
<213>  Homo Sapiens

<400>  5684
tctacacagg gcttccacgt ggaccacacg gccgagctgc ggggaatccg gtggaccagc       60

agtttgcggc gggagacctc ggactatcac cgcacgctga cgcccaccct ggaggcactg      120

ctgcactttc tgctgcgacc cctccagacg ctgagcctgg gcctggagga ggagctattg      180

cagcgaggga tccgggcaag gctgcgggag cacggcatct ccctggctgc ctatggcaca      240

attgtgtcgg ctgagctcac agggagacat aagggaccct tggcagaaag agacttcaaa      300

tcaggccgct gtccagggaa ctccttttcc tgcgggaaca gccagtgtgt gaccaaggtg      360

aacccggagt gtgacgacca ggaggactgc tccgatgggt ccgacgaggc gcactgcgag      420

tgtggcttgc agcctgcctg gaggatggcc ggcaggatcg tgggcggcat ggaagcatcc      480

ccgggggagt ttccgtggca agccagcctt cgagagaaca aggagcactt ctgtggggcc      540

gccatcatca acgccaggtg gctggtgtct gctgctcact gcttcaatga gttccaagac      600

ccgacgaagt gggtggccta cgtgggtgcg acctacctca gcggctcgga ggccagcacc      660

gtgcgggccc aggtggtcca gatcgtcaag caccccctgt acaacgcgga cacggccgac      720

tttgacgtgg ctgtgctgga gctgaccagc cctctgcctt tcggccggca catccagccc      780

gtgtgcctcc cggctgccac acacatcttc ccacccagca agaagtgcct gatctcaggc      840

tggggctacc tcaaggagga cttcctggtc aagccagagg tgctgcagaa agccactgtg      900

gagctgctgg accaggcact gtgtgccagc ttgtacggcc attcactcac tgacaggatg      960

gtgtgcgctg gctacctgga cgggaaggtg gactcctgcc agggtgactc aggaggaccc     1020

ctggtctgcg aggagccctc tggccggttc tttctggctg gcatcgtgag ctggggaatc     1080

gggtgtgcgg aagcccggcg tccaggggtc tatgcccgag tcaccaggct acgtgactgg     1140

atcctggagg ccaccaccaa agccagcatg cctctggccc ccaccatggc tcctgcccct     1200

gccgccccca gcacagcctg gcccaccagt cctgagagcc ctgtggtcag cacccccacc     1260

aaatcgatgc aggccctcag taccgtgcct cttgactggg tcaccgttcc taagctacaa     1320

gaatgtgggg ccaggcctgc aatggagaag cccacccggg tcgtgggcgg gttcggagct     1380

gcctccgggg aggtgccctg gcaggtcagc ctgaaggaag ggtcccggca cttctgcgga     1440

gcaactgtgg tgggggaccg ctggctgctg tctgccgccc actgcttcaa ccacacgaag     1500

gtggagcagg ttcgggccca cctgggcact gcgtccctcc tgggcctggg cgggagcccg     1560

gtgaagatcg ggctgcggcg ggtagtgctg caccccctct acaaccctgg catcctggac     1620

ttcgacctgg ctgtcctgga gctggccagc cccctggcct tcaacaaata catccagcct     1680

gtctgcctgc ccctggccat ccagaagttc cctgtgggcc ggaagtgcat gatctccgga     1740

tggggaaata cgcaggaagg aaatgccacc aagcccgagc tcctgcagaa ggcgtccgtg     1800

ggcatcatag accagaaaac ctgtagtgtg ctctacaact tctccctcac agaccgcatg     1860

atctgcgcag gcttcctgga aggcaaagtc gactcctgcc agggtgactc tgggggcccc     1920

ctggcctgcg aggaggcccc tggcgtgttt tatctggcag ggatcgtgag ctggggtatt     1980

ggctgcgctc aggttaagaa gccgggcgtg tacacgcgca tcaccaggct aaagggctgg     2040

atcctggaga tcatgtcctc ccagcccctt cccatgtctc ccccctcgac cacaaggatg     2100

ctggccacca ccagccccag gacgacagct ggcctcacag tcccgggggc cacacccagc     2160

agacccaccc ctggggctgc cagcagggtg acgggccaac ctgccaactc aaccttatct     2220

gccgtgagca ccactgctag gggacagacg ccatttccag acgccccgga ggccaccaca     2280

cacacccagc taccagactg tggcctggcg ccggccgcgc tcaccaggat tgtgggcggc     2340

agcgcagcgg gccgtgggga gtggccgtgg caggtgagcc tgtggctgcg gcgccgggaa     2400

caccgttgcg gggccgtgct ggtggcagag aggtggctgc tgtcggcggc gcactgcttc     2460

gacgtctacg gggaccccaa gcagtgggcg gccttcctag gcacgccgtt cctgagcggc     2520

gcggaggggc agctggagcg cgtggcgcgc atctacaagc acccgttcta caatctctac     2580

acgctcgact acgacgtggc gctgctggag ctggcggggc cggtgcgtcg cagccgcctg     2640

gtgcgtccca tctgcctgcc cgagcccgcg ccgcgacccc cggacggcac gcgctgcgtc     2700

atcaccggct ggggctcggt gcgcgaagga ggctccatgg cgcggcagct gcagaaggcg     2760

gccgtgcgcc tcctcagcga gcagacctgc cgccgcttct acccagtgca gatcagcagc     2820

cgcatgctgt gtgccggctt cccgcagggt ggcgtggaca gctgctcggg tgacgctggg     2880

ggacccctgg cctgcaggga gccctctgga cggtgggtgc taactggggt cactagctgg     2940

ggctatggct gtggccggcc ccacttccca ggtgtctata cccgggtggc agctgtgaga     3000

ggctggatag gacagcacat ccaggag                                         3027


<210>  5685
<211>  1272
<212>  DNA
<213>  Homo Sapiens

<400>  5685
catccagacc ggattatttt tccaaatcat gcttgtgagg accccccagc agtgctctta       60

gaagtgcagg gcaccttaca gaggcccctg gtccgggaca gccgcacctc ccctgccaac      120

tgcacctggc tcatcctggg cagcaaggaa cagactgtca ccatcaggtt ccagaagcta      180

cacctggcct gtggctcaga gcgcttaacc ctacgctccc ctctccagcc actgatctcc      240

ctgtgtgagg cacctcccag ccctctgcag ctgcccgggg gcaacgtcac catcacttac      300

agctatgctg gggccagagc acccatgggc cagggcttcc tgctctccta cagccaagat      360

tggctgatgt gcctgcagga agagtttcag tgcctgaacc accgctgtgt atctgctgtc      420

cagcgctgtg atggggttga tgcctgtggc gatggctctg atgaagcagg ttgcagctca      480

gaccccttcc ctggcctgac cccaagaccc gtcccctccc tgccttgcaa tgtcaccttg      540

gaggacttct atggggtctt ctcctctcct ggatatacac acctagcctc agtctcccac      600

ccccagtcct gccattggct gctggacccc catgatggcc ggcggctggc cgtgcgcttc      660

acagccctgg acttgggctt tggagatgca gtgcatgtgt atgacggccc tgggccccct      720

gagagctccc gactactgcg tagtctcacc cacttcagca atggcaaggc tgtcactgtg      780

gagacactgt ctggccaggc tgttgtgtcc taccacacag ttgcttggag caatggtcgt      840

ggcttcaatg ccacctacca tgtgcggggc tattgcttgc cttgggacag accctgtggc      900

ttaggctctg gcctgggagc tggcgaaggc ctaggtgagc gctgctacag tgaggcacag      960

cgctgtgacg gctcatggga ctgtgctgac ggcacagatg aggaggactg cccaggctgc     1020

ccacctggac acttcccctg tggggctgct ggcacctctg gtgccacagc ctgctacctg     1080

cctgctgacc gctgcaacta ccagactttc tgtgctgatg gagcagatga gagacgctgt     1140

cggcattgcc agcctggcaa tttccgatgc cgggacgaga agtgcgtgta tgagacgtgg     1200

gtgtgcgatg ggcagccaga ctgtgcggac ggcagtgatg agtgggactg ctcctatgtt     1260

ctgccccgca ag                                                         1272


<210>  5686
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  5686
aaaatctaca ctcgttgcaa actggcaaaa atattctcga gggctggcct ggacaattac       60

tggggcttca gccttggaaa ctggatctgc atggcgtatt atgagagcgg ctacaacacc      120

acagcccaga cggtcctgga tgacggcagc atcgactacg gcatcttcca gatcaacagc      180

ttcgcgtggt gcagacgcgg aaagctgaag gagaacaacc actgccacgt cgcctgctca      240

gccttggtca ctgatgacct cacagatgcg attatctgtg ccaagaaaat tgttaaagag      300

acacaaggaa tgaattattg gcaaggctgg aagaaacact gtgaggggag agacctgtcc      360

gactggaaaa aagactgtga ggtttcc                                          387


<210>  5687
<211>  801
<212>  DNA
<213>  Homo Sapiens

<400>  5687
ggcatggcgg cgccacgcct cccgtcccct ctcctctcag aggagggcgg cgagaacccc       60

gaagcgagcc cggctccagg acctgaagcg ggccccccac tcaatctgtt tacgtccttt      120

ccaggtgact cactgctgtg tggccgaacc cctctgagaa tcgtgggagg agtggacgcg      180

gaggaaggga ggtggccctg gcaggtgagc gtgaggacca aaggcaggca catctgcggc      240

ggcaccctgg tcaccgccac gtgggtgctg acggcaggcc actgcatttc cagccgtttc      300

cattacagtg tcaagatggg agatcggagt gtctataatg aaaacacaag tgtggtggtc      360

tcagtccaaa gagcttttgt ccaccctaag ttctcaacag ttacaaccat tcgaaatgac      420

cttgcccttc tccagctcca acatcctgtg aattttacct caaacatcca gcctatctgc      480

atccctcagg agaatttcca ggtggaaggt aggaccaggt gctgggtgac cggatggggc      540

aaaacaccag aacgagagaa acttgcatca gaaattcttc aggatgtgga ccaatacatc      600

atgtgctatg aggaatgtaa taagataata cagaaggcct tgtcatctac taaggatgta      660

ataataaaag ggatggtctg tggctataaa gaacaaggaa aggattcttg tcaaggagat      720

tctgggggcc gcttggcctg tgaatataat gacacatggg tccaggtagg gattgtgagc      780

tggggcatcg gctgtggtcg c                                                801


<210>  5688
<211>  417
<212>  DNA
<213>  Homo Sapiens

<400>  5688
gccttgcagc ctcccactgc cacagtgctt gtgcagcagg gcacctgcga ggtgattgcg       60

gctcaccgct gctgcaaccg gaaccgcatc gaggagcgct cccagacggt gaaatgctcc      120

tgtttttctg gccaggtggc cggcaccacg cgggcaaagc cctcctgcgt ggacgacctg      180

ctcttggctg cccactgtgc tcgtagagac cctagagctg cactccgcct cctgctccca      240

cagcctccat cgtcctgcag agatggtggt gtcagatgga gccctgcctg ccgggggagg      300

agtgtaaggt gctcccggac ctgtcgggat ggagctgcag cagtggacac aaagtcaaaa      360

ccaccaaggt cacacgatag ctcttggggg tcacggcctg gacaagaaag gcttgac         417


<210>  5689
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  5689
atgctactct gccatggatc ccttcagcac actttccagc agcatcacct gcacagacca       60

gaaggaggga cgtgtgaagt gatagcagca caccgatgtt gtaacaagaa tcgcattgag      120

gagcggtcac aaacagtaaa gtgttcctgt ctacctggaa aagtggctgg aacaacaaga      180

aaccggcctt cttgcgtcga tgcctccata gtgattggga aatggtggtg tgagatggag      240

ccttgcctag aaggagaaga atgtaagaca ctccctgaca attctggatg gatgtgcgca      300

acaggcaaca aaattaagac cacgagaatt cacccaagaa cc                         342


<210>  5690
<211>  534
<212>  DNA
<213>  Homo Sapiens

<400>  5690
cagacagatg gccggaacgg ctacacggcg gtcatcgaag tgaccagcgg gggtccctgg       60

ggcgactggg cctggcctga gatgtgtccc gatggattct tcgccagcgg gttctcgctc      120

aaggtggagc ctccccaagg cattcctggc gacgacactg cactgaatgg gatcaggctg      180

cactgcgcgc gcgggaacgt cctaggcaat acgcacgtgg tagagtccca gtctggaagc      240

tggggcgaat ggagtgagcc gctgtggtgt cgcggcggcg cctacctagt ggctttctcg      300

cttcgcgtgg aggcacccac gaccctcggt gacaacacag cagcgaacaa cgtgcgcttc      360

cgctgttcag acggcgagga actgcagggg cctgggctga gctggggaga ctttggagac      420

tggagtgacc attgccccaa gggcgcgtgc ggcctgcaga ccaagatcca gggacctaga      480

ggcctcggcg atgacactgc gctgaacgac gcgcgcttat tctgctgccg cagt            534


<210>  5691
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5691
aaaaagatgg ctaagaactc ccgcacgagt cttgccagtg cttccaatga aaactatacc       60

ttctgctggc gggtgttctg tgcctgggat tacctcattg gaaacccaga ggctgcagag      120

agcaaaacag ctgccatagt gaacagcatc agggaagcta tattggaaga acaggagaaa      180

aagaaaagca aaaacctggc agtgaccatc tgcctgagg                             219


<210>  5692
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  5692
gagtcgttgg tgaagttttt cattcctcag aggagaaaat ctgtggctgg ggagattgtt       60

ctcattactg gagctgggca tggaataggc aggcagacta cttatgaatt tgcaaaacga      120

cagagcatat tggttctgtg ggatattaat aagcgcggtg tggaggaaac tgcagctgag      180

tgccgaaaac taggcgtcac tgcgcatgcg tatgtggtag actgcagcaa cagagaagag      240

atctatcgct ctctaaatca ggtgaagaaa gaagtgggtg atgtaacaat cgtggtgaat      300

aatgctggga cagtatatcc agccgatctt ctcagcacca aggatgaaga gattaccaag      360

acatttgagg tcaacatcct aggacatttt tggatcacaa aagcacttct tccatcgatg      420

atggagagaa atcatggcca catcgtcaca gtggcttcag tgtgcggcca cgaagggatt      480

ccttacctca tcccatattg ttccagcaaa tttgccgctg ttggctttca cagaggtctg      540

acatcagaac ttcaggcctt gggaaaaact ggtatcaaaa cctcatgtct ctgcccagtt      600

tttgtgaata ctgggttcac caaaaatcca agcacaagat tatggcctgt attggagaca      660

gatgaagtcg taagaagtct gatagatgga atacttacca ataagaaaat gatttttgtt      720

ccatcgtata tcaatatctt tctgagacta cagaagtttc ttcctgaacg cgcctcagcg      780

attttaaatc gtatgcagaa tattcaattt gaagcagtgg ttggccacaa aatcaaaatg      840

aaa                                                                    843


<210>  5693
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5693
ggtgggtcaa aatgtgtgag taacacccca ggatactgca ggacatgttg ccactggggg       60

gagacagcat tgttcatgtg caacgcttcc agaaaatgct gcatcagcta ctccttcctg      120

ccgaagcctg acctaccaca gctcatcggt aaccactggc aatcaaggag aagaaacaca      180

caaaggaaag acaagaagca acaaacgacc gtaacatca                             219


<210>  5694
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  5694
tcatacccct tcagtcactc aatgaagcct cacctacatc cacgcctgta ccacggctgc       60

tatggggaca tcatgaccat gaagacctct ggggccactt gtgatgcaaa cagtgtgatg      120

aactgcggga tccgtggttc tgaaatgttt gctgagatgg atttgagggc cataaaacct      180

taccagactc tgatcaaaga agtcgggcag agacattgcg tggaccctgc tgtcatcgca      240

gccatcatct ccagggaaag ccatggcgga tctgtcctgc aagacggctg ggaccacagg      300

ggacttaaat ttggcttgat gcagcttgat aaacaaacgt accaccctgt cggtgcctgg      360

gatagcaaag agcacctttc acaggctact gggattctaa cagagagaat taaggcaatc      420

cagaaaaaat tccccacgtg gagtgttgct cagcacctca aaggtggtct ctcagctttt      480

aagtcaggaa ttgaagcgat tgccacccca tcggacatag acaatgactt cgtcaatgat      540

atcattgctc gagctaagtt ctataaaaga caaagcttc                             579


<210>  5695
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5695
ctcgcgtctg gtcgcctacc cctcgcggtc cactccgccc agcatggacc tggatccggg       60

gcgccttggt tgcgaattgc caggagggcc ctgagatttg tgttgtcaaa acactggggg      120

gatgattgtt acctgacaaa ccgcctctgg caggacctga agcctcccag tcacgtcgag      180

aacgggcagg agctcaggtt ggcgccgccg gtgcagtggg cattacaggt gcaagggaac      240

cagttgcaaa ctgcagtgct gtgcttgagg atggctcctc ctgagccggc aggctcccgc      300

caaagaatt                                                              309


<210>  5696
<211>  1134
<212>  DNA
<213>  Homo Sapiens

<400>  5696
ctggcagttg agaagactta ctattatcaa ggtgattttc atatttctgg agtcacatac       60

aatgataatt gtgaaaacgc agcttcacaa gccagcacaa atctaagcaa agatattgag      120

actaagatgt taaatgcatt tcaaaattcc agtatatata aggaatatgt caaatctgag      180

gtcatcaaac ttctgcctaa tgccaatggt tcaaatgtgc agttacagct gaaattcaag      240

tttcctccag cagaaggagt tagcatgagg actaaaatca aggctaaatt acatcagatg      300

ttgaaaaaca acatggcatc ctggaatgca gttcctgctt ccattaaact catggaaatc      360

agcaaggctg cttctgaaat gcttaccaac aactgttgtg ggagacaagt agccaacagt      420

atcataactg gcaacaaaat tgtgaatgga aaaagctccc tggagggggc atggccatgg      480

caggccagca tgcaatggaa aggccgtcac tactgtggag cctctctgat cagcagcagg      540

tggctattat ctgcagctca ctgctttgct aagaaaaata attcaaaaga ttggactgtc      600

aactttggag ttgtagtaaa taaaccatat atgacacgga aagtccaaaa cattattttt      660

catgaaaatt atagcagtcc tgggcttcat gatgatattg cccttgtgca gcttgctgaa      720

gaagtttctt ttacagagta cattcgtaag atttgtcttc ctgaagccaa aatgaagctc      780

tcagaaaatg acaatgttgt agttacaggt tggggaacac tttatatgaa tggttcattt      840

ccagtgatac ttcaagaagc ctttttgaag attattgaca acaaaatttg caatgcctca      900

tatgcatact ctggctttgt gactgattca atgttatgtg ctggatttat gtcaggagaa      960

gctgatgcat gtcagaatga ttctggtgga ccactagctt accctgattc cagaaatatc     1020

tggcatcttg ttggaatagt aagctggggt gatggatgtg gtaaaaagaa taagccaggt     1080

gtctatactc gagtgacttc ttatcgcaat tggattacat ccaagactgg actc           1134


<210>  5697
<211>  981
<212>  DNA
<213>  Homo Sapiens

<400>  5697
accagacagg actatgaaga gctagaaaag cagctgaaag aagtctttaa ggagcgaagc       60

accattcttc gtcagctgac aaagacatca agagaacttg atggaattaa agtcaatctt      120

cagtccttaa aaaacgatga gcagtctgcc aaaactgatg ttcagaaact tctggaatta      180

ggacagaaac aaagagaaga aatgaagtct cttcaggagg ccctgcaaaa tcagcttaag      240

gagacatcag agaaagcaga aaaacaccag gctactatta attttttaaa gactgaagtt      300

gaaagaaaga gcaaaatgat ccgagacctc cagaatgaga ataaaagctt gaaaaacaaa      360

ctcttgtcag gaaacaagct ctgtggcatt cacgcagaag agtcaaaaaa aatccaagcc      420

cagctgaagg agcttcgtta tgggaagaag gatttattat ttaaggcgca gcagcttact      480

gatctggaac aaaaattagc tgtagccaaa aatgaactgg agaaagcagc tcttgacagg      540

gagtcacaga tgaaagcaat gaaagagact gtgcagctct gcttgacatc tgttttccgt      600

gatcagcctc ctcccccttt gagtttaatc acatcaaatc caactcggat gttactccca      660

cccaggaata ttgcctctaa gcttccagat gcagcggcca aaagcaagcc tcaacaaagt      720

gcttctggaa acaatgagag ctctcaagtt gagtcaacaa aggaaggaaa tccaagtacc      780

actgcctgtg actctcaaga tgagggcaga ccgtgttcca tgaagcacaa agaaagtccc      840

ccaagtaatg ccactgcaga aaccgagcct atcccacaga aattgcaaat gcctccttgc      900

tctgaatgtg aggtgaaaaa agccccagaa aaaccattga ccagctttga agggatggca      960

gctagagaag aaaaaatact g                                                981


<210>  5698
<211>  1518
<212>  DNA
<213>  Homo Sapiens

<400>  5698
gcctctggca tctacttcta cagtaacaag tacttggacc ctaatgactt tggcgctgtc       60

agggtgggca gagcagttgc tacgacggct gtcatcagtt acgactacct cacttccctg      120

aagagtgtcc cttatggctc agaggagtac ttgcagctga gatctaaggt gcaccttcgc      180

tctgccaggc gtctctgtga gctctgctgt gccaaccggg gcaccttcat caaggtgggc      240

cagcacctgg gggctctgga ctacctgttg ccagaggagt acaccagcac gctgaaggta      300

ctgcacagcc aggctccaca gagcagcatg caagagatcc gccaggtcat ccgagaagat      360

ctgggcaagg agatccatga tttgttccag agcttcgatg acacccctct ggggacggcc      420

tccctggccc aggtccacaa ggcagtgctg catgatgggc ggacggtggc cgtgaaggtc      480

cagcacccaa aggtgcgggc tcagagctcg aaggacattc tcctgatgga ggtgctcgtt      540

ctggctgtga agcagctgtt cccagagttt gagtttatgt ggcttgtgga tgaagccaag      600

aagaacctgc ctttggagct ggatttcctc aatgaaggga ggaatgctga gaaggtgtcc      660

cagatgctca ggcattttga cttcttgaag gtcccccgaa tccactggga cctgtccacg      720

gagcgggtcc tcctgatgga gtttgtggat ggcgggcagg tcaatgacag agactacatg      780

gagaggaaca agatcgacgt caatgagatc tcacgccacc tgggcaagat gtatagtgag      840

atgatcttcg tcaatggctt cgtgcactgc gatccccacc ccggcaatgt actggtgcgg      900

aagcaccccg gcacgggaaa ggcggagatt gtcctgttgg accatgggct ttaccagatg      960

ctcacggaag aattccgcct gaattactgc cacctctggc agtctctgat ctggactgac     1020

atgaagagag tgaaggagta cagccagcga ctgggagccg gggatctcta ccccttgttt     1080

gcctgcatgc tgacggcgcg atcgtgggac tcggtcaaca gaggcatcag ccaagctccc     1140

gtcactgcca ctgaggactt agagattcgc aacaacgcgg ccaactacct cccccagatc     1200

agccatctcc tcaaccacgt gccgcgccag atgctgctca tcttgaagac caacgacctg     1260

ctgcgtggca ttgaggccgc cctgggcacc cgcgccagcg ccagctcctt tctcaacatg     1320

tcacgttgct gcatcagagc gctagctgag cacaagaaga agaatacctg ttcattcttc     1380

agaaggaccc agatctcttt cagcgaggcc ttcaacttat ggcagatcaa cctccatgag     1440

ctcatcctgc gtgtgaaggg gttgaagctg gctgaccggg tcttggccct aatatgctgg     1500

ctgttccctg ctccactc                                                   1518


<210>  5699
<211>  2241
<212>  DNA
<213>  Homo Sapiens

<400>  5699
ttccccaaaa tagaaaggag gagggagata gcacatgttc atgcggaaaa agggcagtcc       60

gataagatga acaccgatga cctagaaaat agctctgtta cctcaaagca gactccccaa      120

ctggtggtct ctgaagatcc aatgatgatg tcagcagtac catcggcaac atcattaaat      180

aaagcattct cgattaacaa agaaatccag cctggacaag ctgggctcat gcaaacagaa      240

cgccctggtg tttccacacc tactgagtca ggtgtcccct cagctgaaga agtatttggt      300

tccagccagc cagagagaat atctcctgaa agtggacttg ccaaggccat gttaaccatt      360

gctatcactg cgactccttc tctgactgtt gatgaaaagg aggaactcct tacaagcact      420

aactttcagc ccattgtaga agagatcaca gaaaccacaa aaggttttct gaagtatatg      480

gataatcaat catttgcaac tgaaagtcag gaaggagttg gtttgggaca ttcaccttca      540

tcctatgtga atactaagga aatgctaacc accaatccaa agactgagaa atttgaagca      600

gacacagacc acaggacaac ttcttttcct ggtgctgagt ccacagcagg cagtgagcct      660

ggaagcctca cccctgataa ggagaagcct tcgcagatga cagctgataa cacccaggct      720

gctgccacca agcaaccact cgaaacttcc gagtacaccc tgagtgttga gccagaaact      780

gatagtctgc tgggagcccc agaagtcaca gtgagtgtca gcacagctgt tccagctgcc      840

tctgccttaa gtgatgagtg ggatgacacc aaattagaga gtgtaagccg gataaggacc      900

cccaagcttg gagacaatga agagactcag gtgagaacgg agatgtctca gacagcacaa      960

gtaagccatg agggtatgga aggaggccag ccttggacag aggctgcaca ggtggctctg     1020

gggctgcctg aaggggaaac acacacgggc acagccctgc taatagcgca tgggaatgag     1080

agatcacctg ctttcactga tcaaagttcc tttaccccca caagtctgat ggaagacatg     1140

aaagtttcca ttgtgaactt gctccaaagt acgggagact tcacggaatc caccaaggaa     1200

aacgatgccc tgtttttctt agaaaccact gtttctgtct ctgtatatga gtctgaggca     1260

gaccaactgt tgggaaatac aatgaaagac atcatcactc aagagatgac aacagctgtt     1320

caagagccag atgccacttt atccatggtg acacaagagc aggttgctac cctcgagctt     1380

atcagagaca gtggcaagac tgaggaagaa aaggaggacc cctctcctgt gtctgacgtt     1440

cctggtgtta ctcagctgtc aagaagatgg gagcctctgg ccactacaat ttcaactaca     1500

gtcgtccctt tgtcttttga agttactccc actgtggaag aacaaatgga cacagtcaca     1560

gggccaaatg aggagttcac accagttctg ggatctccag tgacacctcc tggaataatg     1620

gtgggggaac ccagcatttc ccctgcactt cctgctttgg aggcatcctc tgagagaaga     1680

actgttgttc catctattac tcgtgttaat acagctgcct catatggcct ggaccaactt     1740

gaatctgaag agggagaaga agatgaggat gaagaggatg aagaagatga agatgaagaa     1800

gaggaagatg aggaagaaga tgaggaagat aaagatgcag actcgctgga tgagggcttg     1860

gatggtgaca ctgagctgcc aggttttacc ctccctggta tcacatccca ggaaccaggc     1920

ttagaggagg gaaacatgga cctgttggag ggagctacct accaggtgcc agatgccctc     1980

gagtgggaac agcagaatca aggcctggtg agaagctgga tggaaaaatt aaaagacaag     2040

gctggttaca tgtctgggat gctggtgcct gtaggggttg ggatagctgg agccttgttc     2100

atcttgggag ccctctacag cattaaggtt atgaatcgcc gaaggagaaa tggcttcaaa     2160

aggcataaaa gaaagcagag agaattcaac agcatgcaag atcgagtaat gctcttagcc     2220

gacagctctg aagatgaatt t                                               2241


<210>  5700
<211>  1209
<212>  DNA
<213>  Homo Sapiens

<400>  5700
cagccccttc ttgcccatgg agataaaagt ctgcaggggc ctcaaccccc caggcatcag       60

ctctcagagc cagcccccgc ctaccacaga atcacaccca ccattaccaa ttttgctttg      120

cgtttgtata aagagctggc agcagacgcc cccggaaaca tcttcttctc gccagtgagc      180

atctccacca ccctggccct gctctctctt ggggcccaag ctaacacctc agctctgatc      240

ctggagggcc tgggattcaa cctcacagaa acccctgaag ccgacatcca ccagggcttc      300

cggagcctcc tccacaccct tgccctgccc agccccaaac tcgaactaaa agtaggaaac      360

tccctgttcc tagacaagcg actaaagcct cggcagcact atttggacag catcaaggag      420

ctttatggag cttttgcttt ttctgccaac ttcacagatt ctgttacaac tgggaggcag      480

attaatgact atttgagaag gcaaacatac gggcaagtcg tggactgcct cccggagttc      540

agccaggaca cgttcatggt tcttgccaat tacatcttct tcaaagccaa gtggaagcac      600

cctttcagtc gctaccagac ccagaagcag gaaagtttct ttgtggatga gaggacttct      660

ctccaggtcc ccatgatgca ccaaaaggaa atgcacagat tcctctatga ccaggatttg      720

gcttgcaccg tcctccagat agaatacaga ggaaatgcct tggcgctgct ggtcctccct      780

gacccgggga aaatgaagca ggtggaggct gctctgcagc cacagaccct gagaaaatgg      840

ggccaattgc tcctgcccag tctgttggat ttgcacttgc caaggttttc aatttctgga      900

acatataacc tggaagacat acttccccaa attggtctca ccaacatact caacttagaa      960

gctgacttct caggagtcac tgggcagctc aacaaaacca tctccaaggt gtcacacaag     1020

gcgatggtgg acatgagtga gaaggggacc gaggccgggg ctgcttcagg cctcctctcc     1080

cagcccccat ctctgaacac catgtcagac ccacatgccc acttcaacag gcctttcctc     1140

ttgctccttt gggaggtcac cacccagagc ttactcttcc tgggaaaagt tgtcaaccca     1200

gttgcaggg                                                             1209


<210>  5701
<211>  738
<212>  DNA
<213>  Homo Sapiens

<400>  5701
gcgccggccg agctgcgggt ccgcgtgcgg ctgccggacg gccaggtgac cgaggagagc       60

ctgcaggcgg acagcgacgc ggacagcatc agcctcgagc tgcgcaagcc cgacggcacc      120

ctcgtctcct tcaccgccga cttcaagaag gatgtgaagg tcttccgggc cctgatcctg      180

ggggagctgg agaaggggca gagtcagttc caggccctct gctttgtcac ccagctgcag      240

cacaatgaga tcatccccag tgaggccatg gccaagctcc ggcagaaaaa tccccgggca      300

gtgcggcagg cggaggaggt tcggggtctg gagcatctgc acatggatgt cgctgtcaac      360

ttcagccagg gggccctgct gagcccccat ctccacaacg tgtgtgccga ggccgtggat      420

gccatctaca cccgccagga ggatgtccgg ttctggctgg agcaaggtgt ggacagttct      480

gtgttcgagg ctctgcccaa ggcctcagag caggcggagc tgcctcgctg caggcaggtg      540

ggggaccacg ggaagccctg cgtctgccgc tatggcctga gcctggcctg gtacccctgc      600

atgctcaagt actgccacag ccgcgaccgg cccacgccct acaagtgtgg catccgcagc      660

tgccagaaga gctacagctt cgacttctac gtgccccaga ggcagctgtg tctctgggat      720

gaggatccct acccaggc                                                    738


<210>  5702
<211>  1257
<212>  DNA
<213>  Homo Sapiens

<400>  5702
gtctcctttg gtatccgcaa actctacatg aaaagtctgt taaaaatctt tgcgtgggct       60

accttgagaa tggagcgagg agccaaggag aagaaccacc agctttacaa gccctacacc      120

aacggaatca ttgcaaagga tcccacttca ctagaagaag agatcaaaga gattcgtcga      180

agtggtagta gtaaggctct ggacaacact ccagagttcg agctctctga cattttctac      240

ttttgccgga aaggaatgga gaccattatg gatgatgagg tgacaaagag attctcagca      300

gaagaactgg agtcctggaa cctgctgagc agaaccaatt ataacttcca gtacatcagc      360

cttcggctca cggtcctgtg ggggttagga gtgctgattc ggtactgctt tctgctgccg      420

ctcaggatag cactggcttt cacagggatt agccttctgg tggtgggcac aactgtggtg      480

ggatacttgc caaatgggag gtttaaggag ttcatgagta aacatgttca cttaatgtgt      540

taccggatct gcgtgcgagc gctgacagcc atcatcacct accatgacag ggaaaacaga      600

ccaagaaatg gtggcatctg tgtggccaat catacctcac cgatcgatgt gatcatcttg      660

gccagcgatg gctattatgc catggtgggt caagtgcacg ggggactcat gggtgtgatt      720

cagagagcca tggtgaaggc ctgcccacac gtctggtttg agcgctcgga agtgaaggat      780

cgccacctgg tggctaagag actgactgaa catgtgcaag ataaaagcaa gctgcctatc      840

ctcatcttcc cagaaggaac ctgcatcaat aatacatcgg tgatgatgtt caaaaaggga      900

agttttgaaa ttggagccac agtttaccct gttgctatca agtatgaccc tcaatttggc      960

gatgccttct ggaacagcag caaatacggg atggtgacgt acctgctgcg aatgatgacc     1020

agctgggcca ttgtctgcag cgtgtggtac ctgcctccca tgactagaga ggcagatgaa     1080

gatgctgtcc agtttgcgaa tagggtgaaa tctgccattg ccaggcaggg aggacttgtg     1140

gacctgctgt gggatggggg cctgaagagg gagaaggtga aggacacgtt caaggaggag     1200

cagcagaagc tgtacagcaa gatgatcgtg gggaaccaca aggacaggag ccgctcc        1257


<210>  5703
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5703
agtcccgcgc tgcaggatct gcaagccacg gaggccaatt gcacggtgct gtcggtgcag       60

cagatcggcg aggtgttcga gtgcaccttc acctgtggcg ccgactgcag gggcacctcg      120

cagtacccct gcgtccaggt ctacgtgaac aactctgagt ccaactctag ggcgctgctg      180

cacagcgacg agcaccagct cctgaccaac cccaagtgct cctatatccc tccctgtaag      240

agagaaaatc agaagaattt ggaaagtgtc atgaattggc aacagtactg gaaagatgag      300

attggttccc agccatttac ttgctatttt aatcaacatc aaagaccaga tgatgtgctt      360

ctgcatcgca ctcatgatga g                                                381


<210>  5704
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  5704
gccaatgccc ccagtgcata cccccgccct tcctccacaa agagcacccc tgcctcacag       60

gtgtattccc tcaacaccga ctttgccttc cgcctatacc gcaggctggt tttggagacc      120

ccgagtcaga acatcttctt ctcccctgtg agtgtctcca cttccctggc catgctctcc      180

cttggggccc actcagtcac caagacccag attctccagg gcctgggctt caacctcaca      240

cacacaccag agtctgccat ccaccagggc ttccagcacc tggttcactc actgactgtt      300

cccagcaaag acctgacctt gaagatggga agtgccctct tcgtcaagaa ggagctgcag      360

ctgcaggcaa atttcttggg caatgtcaag aggctgtatg aagcagaagt cttttctaca      420

gatttctcca acccctccat tgcccaggcg aggatcaaca gccatgtgaa aaagaagacc      480

caagggaagg ttgtagacat aatccaaggc cttgaccttc tgacggccat ggttctggtg      540

aaccacattt tctttaaagc caagtgggag aagccctttc accctgaata tacaagaaag      600

aacttcccat tcctggtggg cgagcaggtc actgtgcatg tccccatgat gcaccagaaa      660

gagcagttcg cttttggggt ggatacagag ctgaactgct ttgtgctgca gatggattac      720

aagggagatg ccgtggcctt ctttgtcctc cctagcaagg gcaagatgag gcaactggaa      780

caggccttgt cagccagaac actgagaaag tggagccact cactccagaa aaggtggata      840

gaggtgttca tccccagatt ttccatttct gcctcctaca atctggaaac catcctcccg      900

aagatgggca tccaaaatgt ctttgacaaa aatgctgatt tttctggaat tgcaaagaga      960

gactccctgc aggtttctaa agcaacccac aaggctgtgc tggatgtcag tgaagagggc     1020

actgaggcca cagcagctac caccaccaag ttcatagtcc gatcgaagga tggcccctct     1080

tacttcactg tctccttcaa taggaccttc ctgatgatga ttacaaataa agccacagac     1140

ggtattctct ttctagggaa agtggaaaat cccactaaat cc                        1182


<210>  5705
<211>  195
<212>  DNA
<213>  Homo Sapiens

<400>  5705
gtgaccagtt ctaccagtta cttcctacct tactggctct ttggatccca gatggggaag       60

ccagtgtcat tcagcacatt ccggaggtgc aactaccctg tgcggggaga gggacacagt      120

ctgatcatgg tggaagaatg tgggcgctat gccagcttca atgccatccc aagcctggcc      180

tggcagatgt gcaca                                                       195


<210>  5706
<211>  912
<212>  DNA
<213>  Homo Sapiens

<400>  5706
gaccactact cgccctctgg aaggcacagg ctcggcccct cgccggaacc ggcggctagt       60

tcccagcagg ctgaggccgt ccgcaagagg ctccggcggc ggagggaggg aggggcgcat      120

gcaaaggatt gtggaacagc accgcttaag gatgtgttgc aagggtctcg gattataggg      180

ggcaccgaag cacaagctgg cgcatggccg tgggtggtga gcctgcagat taaatatggc      240

cgtgttcttg ttcatgtatg tgggggaacc ctagtgagag agaggtgggt cctcacagct      300

gcccactgca ctaaagacgc tagcgatcct ttaatgtgga cagctgtgat tggaactaat      360

aatatacatg gacgctatcc tcataccaag aagataaaaa ttaaagcaat cattattcat      420

ccaaacttca ttttggaatc ttatgtaaat gatattgcac tttttcactt aaaaaaagca      480

gtgaggtata atgactatat tcagcctatt tgcctacctt ttgatgtttt ccaaatcctg      540

gacggaaaca caaagtgttt tataagtggc tggggaagaa caaaagaaga aggtaacgct      600

acaaatattt tacaagatgc agaagtgcat tatatttctc gagagatgtg taattctgag      660

aggagttatg ggggaataat tcctaacact tcattttgtg caggtgatga agatggagct      720

tttgatactt gcaggggtga cagtggggga ccattaatgt gctacttacc agaatataaa      780

agattttttg taatgggaat taccagttac ggacatggct gtggtcgaag aggttttcct      840

ggtgtctata ttgggccatc cttctaccaa aagtggctga cagagcattt cttccatgca      900

agcactcaag gc                                                          912


<210>  5707
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  5707
tacgaggttt ttaacatcat cagcccaagc aacaatggtg gcaatgttca ggagacagtg       60

acaattgata atgaaaaaaa taccgccatc attaacatcc atgcaggatc atgctcttct      120

accacaattt ttgactataa acatggctac attgcatcca gggtgctctc ccgaagagcc      180

tgctttatcc tgaagatgga ccatcagaac atccctcctc tgaacaatct ccaatggtac      240

atctatgaga aacaggctct ggacaacatg ttctccagca aatacacctg ggtcaagtac      300

aaccctctgg agtctctgat caaagacgtg gattggttcc tgcttgggtc acccattgag      360

aaactctgca aacatatccc tttgtataag ggggaagtgg ttgaaaacac acataatgtc      420

ggtgctggag gctgtgcaaa ggctgggctc ctgggcatct tgggaatttc aatctgtgca      480

gacattcatg tt                                                          492


<210>  5708
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  5708
caggtcactg gagttctgga tgattgcttg tgtgatattg acagcatcga taacttcaat       60

acctacaaaa tcttccccaa aataaaaaaa ttgcaagaga gagactattt tcgttattac      120

aaggttaatc tgaagcgacc ttgtcctttc tgggcagaag atggccactg ttcaataaaa      180

gactgtcatg tggagccctg tccagagagt aaaattccgg ttggaataaa agctgggcat      240

tctaataagt acttgaaaat ggcaaacaat accaaagaat tagaagtttg tgagcaagct      300

aataaactgg gagcaattaa cagcacatta agtaatcaaa gcaaagaagc tttcattgac      360

tgggcaagat atgatgattc acgggatcac ttttgtgaac ttgatgatga gagatctcca      420

gctgctcagt atgtagacct attgctgaac ccagagcgtt acactggcta taaagggacc      480

tctgcatgga gagtgtggaa cagcatctat gaagagaact gtttcaagcc tcgatctgtt      540

tatcgtcctt taaatcctct ggcgcctagc cgaggcgaag atgatggaga atcattctac      600

acatggctag aaggtttgtg tctggagaaa agagtcttct ataagcttat atcgggactt      660

catgctagca tcaatttaca tctatgcgca aattatcttt tggaagaaac ctggggtaag      720

cccagttggg gacctaatat taaagaattc aaacaccgct ttgaccctgt ggaaaccaag      780

ggagaaggtc caagaaggct caagaatctt tactttttat acttgattga gcttcgagct      840

ttgtcaaagg tggctccata ttttgagcgc tcaattgtcg atctttacac tggaaatgca      900

gaagaagatg ctgacacaaa aactcttcta ctgaatatct ttcaagatac aaagtccttt      960

cccatgcact ttgatgagaa atccatgttt gcaggtgaca aaaaaggggc caagtcacta     1020

aaggaggaat tccgattaca tttcaagaat atctcccgta taatggactg tgttggatgt     1080

gacaaatgca gattatgggg aaaattacag actcagggtt taggaactgc cctgaagata     1140

ttattctctg aaaaagaaat ccaaaagctt ccagagaata gtccatctaa aggcttccaa     1200

ctcacccgac aggaaatagt tgctctttta aatgcttttg gaaggctttc tacaagtata     1260

agagacttac agaattttaa agtcttatta caacacagta gg                        1302


<210>  5709
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  5709
gccagcacag gccagccaga agatgacact gagactacag gtttggaagg cggcgttgcc       60

atgccaggtg ccgaagatga tgtggtgact ccaggaacca gcgaagaccg ctataagtct      120

ggcttgacaa ctctggtggc aacaagtgtc aacagtgtaa caggcattcg catcgaggat      180

ctgccaactt cagaaagcac agtccacgcg caagaacaaa gtccaagcgc cacagcctca      240

aacgtggcca ccagtcactc cacggagaaa gtggatggag acacacagac aacagttgag      300

aaagatggtt tgtcaacagt gaccctg                                          327


<210>  5710
<211>  2988
<212>  DNA
<213>  Homo Sapiens

<400>  5710
atgaagccag gctgtgcggc aggatctcca gggaatgaat ggattttctt cagcactgat       60

gaaataacca cacgctatag gaatacaatg tccaacgggg gattgcaaag atctgtcatc      120

ctgtcagcac ttattctgct acgagctgtt actggattct ctggagatgg aagagctata      180

tggtctaaaa atcctaattt tactccggta aatgaaagtc agctgtttct ctatgacact      240

ttccctaaaa actttttctg gggtattggg actggagcat tgcaagtgga agggagttgg      300

aagaaggatg gaaaaggacc ttctatatgg gatcatttca tccacacaca ccttaaaaat      360

gtcagcagca cgaatggttc cagtgacagt tatatttttc tggaaaaaga cttatcagcc      420

ctggatttta taggagtttc tttttatcaa ttttcaattt cctggccaag gcttttcccc      480

gatggaatag taacagttgc caacgcaaaa ggtctgcagt actacagtac tcttctggac      540

gctctagtgc ttagaaacat tgaacctata gttactttat accactggga tttgcctttg      600

gcactacaag aaaaatatgg ggggtggaaa aatgatacca taatagatat cttcaatgac      660

tatgccacat actgtttcca gatgtttggg gaccgtgtca aatattggat tacaattcac      720

aacccatatc tagtggcttg gcatgggtat gggacaggta tgcatgcccc tggagagaag      780

ggaaatttag cagctgtcta cactgtggga cacaacttga tcaaggctca ctcgaaagtt      840

tggcataact acaacacaca tttccgccca catcagaagg gttggttatc gatcacgttg      900

ggatctcatt ggatcgagcc aaaccggtcg gaaaacacga tggatatatt caaatgtcaa      960

caatccatgg tttctgtgct tggatggttt gccaacccta tccatgggga tggcgactat     1020

ccagagggga tgagaaagaa gttgttctcc gttctaccca ttttctctga agcagagaag     1080

catgagatga gaggcacagc tgatttcttt gccttttctt ttggacccaa caacttcaag     1140

cccctaaaca ccatggctaa aatgggacaa aatgtttcac ttaatttaag agaagcgctg     1200

aactggatta aactggaata caacaaccct cgaatcttga ttgctgagaa tggctggttc     1260

acagacagtc gtgtgaaaac agaagacacc acggccatct acatgatgaa gaatttcctc     1320

agccaggtgc ttcaagcaat aaggttagat gaaatacgag tgtttggtta tactgcctgg     1380

tctctcctgg atggctttga atggcaggat gcttacacca tccgccgagg attattttat     1440

gtggatttta acagtaaaca gaaagagcgg aaacctaagt cttcagcaca ctactacaaa     1500

cagatcatac gagaaaatgg tttttcttta aaagagtcca cgccagatgt gcagggccag     1560

tttccctgtg acttctcctg gggtgtcact gaatctgttc ttaagcccga gtctgtggct     1620

tcgtccccac agttcagcga tcctcatctg tacgtgtgga acgccactgg caacagactg     1680

ttgcaccgag tggaaggggt gaggctgaaa acacgacccg ctcaatgcac agattttgta     1740

aacatcaaaa aacaacttga gatgttggca agaatgaaag tcacccacta ccggtttgct     1800

ctggattggg cctcggtcct tcccactggc aacctgtccg cggtgaaccg acaggccctg     1860

aggtactaca ggtgcgtggt cagtgagggg ctgaagcttg gcatctccgc gatggtcacc     1920

ctgtattatc cgacccacgc ccacctaggc ctccccgagc ctctgttgca tgccgacggg     1980

tggctgaacc catcgacggc cgaggccttc caggcctacg ctgggctgtg cttccaggag     2040

ctgggggacc tggtgaagct ctggatcacc atcaacgagc ctaaccggct aagtgacatc     2100

tacaaccgct ctggcaacga cacctacggg gcggcgcaca acctgctggt ggcccacgcc     2160

ctggcctggc gcctctacga ccggcagttc aggccctcac agcgcggggc cgtgtcgctg     2220

tcgctgcacg cggactgggc ggaacccgcc aacccctatg ctgactcgca ctggagggcg     2280

gccgagcgct tcctgcagtt cgagatcgcc tggttcgccg agccgctctt caagaccggg     2340

gactaccccg cggccatgag ggaatacatt gcctccaagc accgacgggg gctttccagc     2400

tcggccctgc cgcgcctcac cgaggccgaa aggaggctgc tcaagggcac ggtcgacttc     2460

tgcgcgctca accacttcac cactaggttc gtgatgcacg agcagctggc cggcagccgc     2520

tacgactcgg acagggacat ccagtttctg caggacatca cccgcctgag ctcccccacg     2580

cgcctggctg tgattccctg gggggtgcgc aagctgctgc ggtgggtccg gaggaactac     2640

ggcgacatgg acatttacat caccgccagt ggcatcgacg accaggctct ggaggatgac     2700

cggctccgga agtactacct agggaagtac cttcaggagg tgctgaaagc atacctgatt     2760

gataaagtca gaatcaaagg ctattatgca ttcaaactgg ctgaagagaa atctaaaccc     2820

agatttggat tcttcacatc tgattttaaa gctaaatcct caatacaatt ttacaacaaa     2880

gtgatcagca gcaggggctt cccttttgag aacagtagtt ctagatgcag tcagacccaa     2940

gaaaatacag agtgcactgt ctgcttattc cttgtgcaga agaaacca                  2988


<210>  5711
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5711
tcccgcgggc cagcgcacta cgagatgctg ggtcgctgcc gcatggtgtg cgacccgcat       60

gggccccgtg gccctggtcc cgacggcgcg cctgcttccg tgcccccctt cccgccaggc      120

gccaagggag aggtgggccg gcgcgggaaa gcaggcctgc gggggccccc tggaccacca      180

ggtccaagag ggcccccagg agaacccggc aggccaggcc ccccgggccc tcccggtcca      240

ggtccgggcg gggtggcgcc cgctgccggc tacgtgcctc gcattgcttt ctacgcgggc      300

ctgcggcggc cccacgaggg ttacgaggtg ctgcgcttcg acgacgtggt gaccaacgtg      360

ggcaacgcct acgaggcagc cagcggcaag tttacttgcc ccatgccagg cgtctacttc      420

ttcgcttacc acgtgctcat gcgcggcggc gacggcacca gcatgtgggc cgacctcatg      480

aagaacggac aggtccgggc cagcgccatt gctcaggacg cggaccagaa ctacgactac      540

gccagcaaca gcgtcattct gcacctggac gtgggcgacg aggtcttcat caagctggac      600

ggcgggaaag tgcacggcgg caacaccaac aagtacagca ccttctccgg cttcatcatc      660

taccccgac                                                              669


<210>  5712
<211>  2271
<212>  DNA
<213>  Homo Sapiens

<400>  5712
gggtacaagg cggaggtgat ggtcagccag gtgtactcag gcagtctgcg tgtactcaat       60

cgccacttct cccaggatct tacccgccgg gaatctagtg ccttccgcag tgaaaccgcc      120

aaagcccaga agatgctcaa ggagctcatc accagcaccc gcctgggaac ttactacaac      180

tccagctccg tctattcctt tggggaggga cccctcacct gcttcttctg gttcattctc      240

caaatccccg agcaccgccg gctgatgctg agccccgagg tggtgcaggc actgctggtg      300

gaggagctgc tgtccacagt caacagctcg gctgccgtcc cctacagggc cgagtacgaa      360

gtggaccccg agggcctagt gatcctggaa gccagtgtga aagacatagc tgcattgaat      420

tccacgctgg gttgttaccg ctacagctac gtgggccagg gccaggtcct ccggctgaag      480

gggcctgacc acctggcctc cagctgcctg tggcacctgc agggccccaa ggacctcatg      540

ctcaaactcc ggctggagtg gacgctggca gagtgccggg accgactggc catgtatgac      600

gtggccgggc ccctggagaa gaggctcatc acctcggtgt acggctgcag ccgccaggag      660

cccgtggtgg aggttctggc gtcgggggcc atcatggcgg tcgtctggaa gaagggcctg      720

cacagctact acgacccctt cgtgctctcc gtgcagccgg tggtcttcca ggcctgtgaa      780

gtgaacctga cgctggacaa caggctcgac tcccagggcg tcctcagcac cccgtacttc      840

cccagctact actcgcccca aacccactgc tcctggcacc tcacggtgcc ctctctggac      900

tacggcttgg ccctctggtt tgatgcctat gcactgagga ggcagaagta tgatttgccg      960

tgcacccagg gccagtggac gatccagaac aggaggctgt gtggcttgcg catcctgcag     1020

ccctacgccg agaggatccc cgtggtggcc acggccggga tcaccatcaa cttcacctcc     1080

cagatctccc tcaccgggcc cggtgtgcgg gtgcactatg gcttgtacaa ccagtcggac     1140

ccctgccctg gagagttcct ctgttctgtg aatggactct gtgtccctgc ctgtgatggg     1200

gtcaaggact gccccaacgg cctggatgag agaaactgcg tttgcagagc cacattccag     1260

tgcaaagagg acagcacatg catctcactg cccaaggtct gtgatgggca gcctgattgt     1320

ctcaacggca gcgacgaaga gcagtgccag gaaggggtgc catgtgggac attcaccttc     1380

cagtgtgagg accggagctg cgtgaagaag cccaacccgc agtgtgatgg gcggcccgac     1440

tgcagggacg gctcggatga ggagcactgt gactgtggcc tccagggccc ctccagccgc     1500

attgttggtg gagctgtgtc ctccgagggt gagtggccat ggcaggccag cctccaggtt     1560

cggggtcgac acatctgtgg gggggccctc atcgctgacc gctgggtgat aacagctgcc     1620

cactgcttcc aggaggacag catggcctcc acggtgctgt ggaccgtgtt cctgggcaag     1680

gtgtggcaga actcgcgctg gcctggagag gtgtccttca aggtgagccg cctgctcctg     1740

cacccgtacc acgaagagga cagccatgac tacgacgtgg cgctgctgca gctcgaccac     1800

ccggtggtgc gctcggccgc cgtgcgcccc gtctgcctgc ccgcgcgctc ccacttcttc     1860

gagcccggcc tgcactgctg gattacgggc tggggcgcct tgcgcgaggg cgccctacgg     1920

gcggatgctg tggccctatt ttatggatgg agaaaccaag gctcagagac atgttgctgc     1980

cccatcagca acgctctgca gaaagtggat gtgcagttga tcccacagga cctgtgcagc     2040

gaggtctatc gctaccaggt gacgccacgc atgctgtgtg ccggctaccg caagggcaag     2100

aaggatgcct gtcagggtga ctcaggtggt ccgctggtgt gcaaggcact cagtggccgc     2160

tggttcctgg cggggctggt cagctggggc ctgggctgtg gccggcctaa ctacttcggc     2220

gtctacaccc gcatcacagg tgtgatcagc tggatccagc aagtggtgac c              2271


<210>  5713
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  5713
tgcactgccg tgcccgtgag cgcactgggc aacggcagcc tggcacccgg ccttcctgcc       60

cccgagctcg cccgcctgct ggcccgggtg ccctgccctg agatctacga tggcgactgg      120

ctgttggccc gagaggtggc cgtgcgttac ctccgc                                156


<210>  5714
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  5714
ggagaacatg caaaagaggg agaatgccct ccccataaga acccatgcaa agagctgtgc       60

cagggtgatg aattgtgtcc ggctgaacag aagtgctgca ccacaggctg tggtcggatc      120

tgccgagaca ttcctaaggg gaggaaaaga gattgcccta gggttattcg gaaacaatcc      180

tgtttgaaaa ggtgcatcac tgatgagaca tgtccaggtg taaagaaatg ctgcacgctt      240

ggctgcaaca agagctgtgt agtcccaatc tctaaacaga agctggcaga gtttggtggt      300

gaatgtcccg ctgaccccct tccgtgtgag gagctgtgtg atggggatgc atcctgtccc      360

caggggcata aatgctgcag caccggctgt ggccgcacct gcctcggaga cattgaggga      420

gggcggggcg gtgattgtcc aaaagttctg gtgggcctgt gcattgttgg ctgtgtgatg      480

gatgagaatt gtcaagctgg agaaaaatgt tgcaagtcag gctgtggccg cttctgtgtc      540

ccaccagtcc tgcccccaaa actgaccatg aaccccaact ggactgtgag gtctgattcc      600

gaattagaga tcccggtgcc c                                                621


<210>  5715
<211>  777
<212>  DNA
<213>  Homo Sapiens

<400>  5715
tacgtgatcg tgagctccgt gtcttgggcc gtcaccaacg aggtggacga ggagctggac       60

agcgcctcca ctgaggaggc tatgcccgcg ctgctagagg attcgggcag catctggcag      120

caaagcttcc ccgcctctgc ccacaaggag gacgcgcacc tgcggccccg ggcgggcgcc      180

gcccgggcca ggcagccccc cgcgccaccc gggatgttct cctaccggcg cgagggcggc      240

cagacggcca gtgcgccccc gggccctaga ctgcgcgccg ccaccgcccg ctccctggcc      300

catgccagcg tctggggctg cctggccacc gtgtccaccc acaagaagat ccaaggactg      360

ccatttggga actgcctgcc cgtcagtgat ggccccttca acaatagcac tgggattcct      420

ttcttctaca tgacagccaa ggaccccgtg gtggctgatc tgatgaagaa ccccatggcc      480

tcgctgatgc tgccagaatc agaaggggag ttctgcagaa aaaacatcgt tgatccggaa      540

gatccccgat gtgtccagtt aacgctcact ggccagatga tcgcagtgtc tccagaagaa      600

gtagaatttg ccaagcaagc catgttttca aggcacccag ggatgaggaa gtggcctcgt      660

caatatgaat ggttctttat gaagatgagg atagaacata tctggcttca gaaatggtat      720

ggaggcgcat ccagtatttc aagggaggaa tatttcaaag cagttcccag aaaggcc         777


<210>  5716
<211>  1224
<212>  DNA
<213>  Homo Sapiens

<400>  5716
ctgagccccc agcccggagc aggtcacgat gagggcccag gctctggatg ggctgccaaa       60

gggaccgtgc ggggctggaa ccggagagcc cgagagagcc ctgggcatgt gtcagagccg      120

gacaggaccc agctgagcca ggacctgggt gggggcaccc tggccatgga cacgctgcca      180

gataacagga ccagggtggt ggaggacaac cacagctatt atgtgtcccg tctctatggc      240

cccagcgagc cccacagccg ggaactgtgg gtagatgtgg ccgaggccaa ccggagccaa      300

gtgaagatcc acacaatact ctccaacacc caccggcagg cttcgagagt ggtcttgtcc      360

tttgatttcc ctttctacgg gcatcctctg cggcagatca ccatggcaac tggaggcttc      420

atcttcatgg gggacgtgat ccatcggatg ctcacagcta ctcagtatgt ggcgcccctg      480

atggccaact tcaaccctgg ctactccgac aactccacag ttgtttactt tgacaatggg      540

acagtctttg tggttcagtg ggaccacgtt tatctccaag gctgggaaga caagggcagt      600

ttcaccttcc aggcagctct gcaccatgac ggccgcattg tctttgccta taaagagatc      660

cctatgtctg tcccggaaat cagctcctcc cagcatcctg tcaaaaccgg cctatcggat      720

gccttcatga ttctcaatcc atccccggat gtgccagaat ctcggcgaag gagcatcttt      780

gaatatcacc gcatagagct ggaccccagc aaggtcacca gcatgtcggc cgtggagttc      840

accccattgc cgacctgcct gcagcatagg agctgtgacg cctgcatgtc ctcagacctg      900

accttcaact gcagctggtg ccatgtcctc cagagatgct ccagtggctt tgaccgctat      960

cgccaggagt ggatggacta tggctgtgca caggaggcag agggcaggat gtgcgaggac     1020

ttccaggatg aggaccacga ctcagcctcc cctgacactt ccttcagccc ctatgatgga     1080

gacctcacca ctacctcctc ctccctcttc atcgacagcc tcaccacaga agatgacacc     1140

aagttgaatc cctatgcagg aggagacggc cttcagaaca acctgtcacc caagacaaag     1200

ggcactcctg tgcacctggg cacc                                            1224


<210>  5717
<211>  2148
<212>  DNA
<213>  Homo Sapiens

<400>  5717
gagccccccg gcctgaccca gctgtccccg ggggcgcccc cgcaggcccc cgacttgctc       60

tacgctgacg ggctgcgcgc ctacgcggcc ggggcttggg cgccggccgt ggcgctgctg      120

cgggaggcgc tgcggagcca ggcggcgctg ggccgggtgc ggctggattg cggggcgagc      180

tgcgcggccg atccgggcgc cgcgctcccc gccgtgcttc tcggggcccc ggagcccgac      240

tccgggccgg gacccacgca ggggtcctgg gagcgacagc ttctccgtgc agcgctccgc      300

cgcgcagact gcctgaccca gtgcgcagca cggaggctgg gccccggggg cgcggcgcgg      360

cttcgcgtgg ggagcgcgct ccgggacgcc ttccgccgtc gggagcccta caactacctg      420

cagagggcct attaccagtt gaagaagctg gatctggcag ctgcggcagc acacaccttc      480

tttgtagcaa accccatgca cctgcagatg cgggaggaca tggctaagta cagacgaatg      540

tcgggagttc ggccccagag cttccgggac ctggagacgc ccccacactg ggcagcctat      600

gacactggcc tggagctact ggggcgccag gaggcaggac tggcactgcc caggctagag      660

gaggctcttc aggggagcct ggcccagatg gagagctgcc gtgctgactg tgaggggcct      720

gaggagcagc agggggctga agaagaggag gatggggctg cgagccaggg gggcctctat      780

gaggccattg caggacactg gattcaggtc ctgcagtgcc ggcaacgctg tgtgggggaa      840

acagccacac gccctggtcg cagcttccct gtcccagact tccttcccaa ccagctgagg      900

cggctacatg aggcccatgc tcaggtgggc aatctgtccc aggctataga aaatgtcctg      960

agtgtcctgc tcttctaccc ggaggatgag gctgccaaga gggctctgaa ccagtaccag     1020

gcccagctgg gagagccgag acctggcctc ggacccagag aggacatcca gcgcttcatc     1080

ctccgatccc tgggggagaa gaggcagctc tactatgcca tggagcacct ggggaccagc     1140

ttcaaggatc ctgacccctg gacccctgca gctctcatcc ctgaggcact tagagaaaag     1200

ctcagagagg atcaagagaa gaggccttgg gaccatgagc ccgtgaagcc aaagcccttg     1260

acctactgga aggatgtcct tctcctggag ggtgtgacct tgacccagga ttccaggcag     1320

ctgaatgggt cggagcgggc ggtgttggat gggctgctca ccccagccga gtgtggggtg     1380

ctgctgcagc tggctaagga tgcagctggg gctggagcca ggtctggcta tcgtggtcgc     1440

cgctcccctc acacccccca tgaacgcttc gaggggctca cggtgcttaa ggctgcgcag     1500

ctggcccggg ctgggacagt gggcagtcag ggtgctaagc tgcttctgga ggtgagcgag     1560

cgggtgcgga ccttgaccca ggcctacttc tccccggaac ggcccctgca tctgtccttc     1620

acccacctgg tgtgccgcag cgccatagaa ggagagcaag agcagcgcat ggacctgagt     1680

cacccagtgc acgcagacaa ctgcgtcctg gaccctgaca cgggagagtg ctggcgggag     1740

cccccagcct acacctatcg ggactacagc ggactcctct acctcaacga tgacttccag     1800

ggtggggacc tgttcttcac ggagcccaac gccctcactg tcacggctcg ggtgcgtcct     1860

cgctgtgggc gccttgtggc cttcagctcc ggtgtcgaga atccccatgg ggtgtgggcc     1920

gtgactcggg gacggcgctg tgccctggca ctgtggcaca cgtgggcacc tgagcacagg     1980

gagcaggagt ggatagaagc caaagaactg ctgcaggagt cacaggagga ggaggaagag     2040

gaagaggaag aaatgcccag caaagaccct tccccagagc cccctagccg caggcaccag     2100

agggtccaag acaagactgg aagggcacct cgggttcggg aggagctg                  2148


<210>  5718
<211>  996
<212>  DNA
<213>  Homo Sapiens

<400>  5718
tatgatagat ccttagccca acacagacaa gagattgtgg acaagtcagt gagtccatgg       60

agcctggaga cgtattccta taacatatac caccccatgg gagagatcta tgagtggatg      120

agagagatca gtgagaagta caaggaagtg gtgacacagc atttcctagg agtgacctat      180

gagacccacc ccatatatta tctgaagatc agccaaccat ctggtaatcc caagaaaatc      240

atttggatgg actgtggaat tcacgccaga gaatggattg ctcctgcttt ttgccaatgg      300

ttcgtcaaag aaattctaca aaaccataaa gacaactcaa ggatacgcaa gctccttagg      360

aacctggact tctatgtcct tccagttctt aacatagatg gttatatcta cacttggaca      420

actgatcgtc tttggaggaa atcccgttca ccccataata atggcacatg ttttgggacg      480

gatctcaatc gaaatttcaa tgcttcttgg tgtagtattg gtgcctctag aaactgccaa      540

gatcaaacat tctgtgggac agggccagtg tctgaaccag agactaaagc tgttgccagc      600

ttcatagaga gcaagaagga tgatattttg tgcttcctga ccatgcactc ttatgggcag      660

ttaattctca caccttacgg ctacaccaaa aataaatcaa gtaaccaccc agaaatgatt      720

caagttggac agaaggcagc aaatgcattg aaagcaaagt atggaaccaa ttatagagtt      780

ggatcgagtg cagatatttt atatgcctca tcagggtctt caagagattg ggcccgagac      840

attgggattc ccttctcata tacgtttgag ctgagggaca gtggaacata tgggtttgtt      900

ctgccagaag ctcagatcca gcccacctgt gaggagacca tggaggctgt gctgtcagtc      960

ctggatgatg tgtatgcgaa acactggcac tcggac                                996


<210>  5719
<211>  321
<212>  DNA
<213>  Homo Sapiens

<400>  5719
ctggagaact tcactgcatt catacctggc catcgctgct gggtccacat cctggacaat       60

gacactgtct ctgacaatga cactggggcc ctcagccaag atgcactctt gagaatctcc      120

atcccactgg actcaaacat gaggccagag aagtgtcgtc gctttgttca tcctcagtgg      180

cagctccttc acctgaatgg gaccttcccc aacacaagtg acgcagacat ggagccctgt      240

gtggatggct gggtgtatga cagaatctcc ttctcatcca ccatcgtgac tgagtgggat      300

ctggtatgtg actctcaatc a                                                321


<210>  5720
<211>  732
<212>  DNA
<213>  Homo Sapiens

<400>  5720
ggctgcgccg aggccgggcg ctgctgtccc ggccgggacc ccgcctgctt cgcccgcggc       60

tggaggctgg acagggtcta cgggacgtgt ttctgcgacc aagcctgtcg cttcaccggg      120

gactgctgct tcgactacga cagggcgtgc ccagctcgcc cgtgcttcgt gggggaatgg      180

agcccctgga gtggttgtgc agaccagtgc aagcctacaa cccgtgtgcg gaggcgctcg      240

gtgcagcagg agcctcagaa cggcggggcg ccctgcccac ccctggaaga gagagctggc      300

tgcctggagt actccacccc gcagggccag gactgcgggc acacctatgt tcctgccttt      360

ataactacct ctgcattcaa caaggagaga acacgacaag ctacgtctcc acactggtct      420

acacacacag aggatgctgg atactgtatg gagtttaaga cagagtcctt gactcctcac      480

tgtgctctgg aaaactggcc cttgactaga tggatgcagt atctccgaga gggatacacg      540

gtgtgtgtgg attgtcagcc tccagctatg aactctgtga gccttcgttg ttctggagat      600

ggcctggact ccgatggaaa tcagactctc cattggcaag caattggtaa tcctcggtgt      660

caaggaactt ggaaaaaagt tcggcgagta gaccagtgtt cttgtccagc tgttcacagt      720

tttattttta ta                                                          732


<210>  5721
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  5721
ctaaagccga gcttctcacc aaggaattat aaagctttga gcgaggtcca aggatggaag       60

caaaggatgg cagccaagga gcttgcaagg cagaacatgg acttaggctt taagctgctc      120

aagaagctgg ccttttacaa ccctggcagg aacatcttcc tatccccctt gagcatctct      180

acagctttct ccatgctgtg cctgggtgcc caggacagca ccctggacga gatcaagcag      240

gggttcaact tcagaaagat gccagaaaaa gatcttcatg agggcttcca ttacatcatc      300

cacgagctga cccagaagac ccaggacctc aaactgagca ttgggaacac gctgttcatt      360

gaccagaggc tgcagccaca gcgtaagttt ttggaagatg ccaagaactt ttacagtgcc      420

gaaaccatcc ttaccaactt tcagaatttg gaaatggctc agaagcagat caatgacttt      480

atcagtcaaa aaacccatgg gaaaattaac aacctgatcg agaatataga ccccggcact      540

gtgatgcttc ttgcaaatta tattttcttt cgagccaggt ggaaacatga gtttgatcca      600

aatgtaacta aagaggaaga tttctttctg gagaaaaaca gttcagtcaa ggtgcccatg      660

atgttccgta gtggcatata ccaagttggc tatgacgata agctctcttg caccatcctg      720

gaaataccct accagaaaaa tatcacagcc atcttcatcc ttcctgatga gggcaagctg      780

aagcacttgg agaagggatt gcaggtggac actttctcca gatggaaaac attactgtca      840

cgcagggtcg tagacgtgtc tgtacccaga ctccacatga cgggcacctt cgacctgaag      900

aagactctct cctacatagg tgtctccaaa atctttgagg aacatggtga tctcaccaag      960

atcgcccctc atcgcagcct gaaagtgggc gaggctgtgc acaaggctga gctgaagatg     1020

gatgagaggg gtacggaagg ggccgctggc accggagcac agactctgcc catggagaca     1080

ccactcgtcg tcaagataga caaaccctat ctgctgctga tttacagcga gaaaatacct     1140

tccgtgctct tcctgggaaa gattgttaac cctattggaa aa                        1182


<210>  5722
<211>  1812
<212>  DNA
<213>  Homo Sapiens

<400>  5722
agcaccctgg tccctctgcg gctccgccat cgacagctgg ggctgcaggc caagggctgg       60

aacttcatgc tggaggattc caccttctgg atcttcgggg gctccatcca ctatttccgt      120

gtgcccaggg agtactggag ggaccgcctg ctgaagatga aggcctgtgg cttgaacacc      180

ctcaccacct atgttccgtg gaacctgcat gagccagaaa gaggcaaatt tgacttctct      240

gggaacctgg acctggaggc cttcgtcctg atggccgcag agatcgggct gtgggtgatt      300

ctgcgtccag gcccctacat ctgcagtgag atggacctcg ggggcttgcc cagctggcta      360

ctccaagacc ctggcatgag gctgaggaca acttacaagg gcttcaccga agcagtggac      420

ctttattttg accacctgat gtccagggtg gtgccactcc agtacaagcg tgggggacct      480

atcattgccg tgcaggtgga gaatgaatat ggttcctata ataaagaccc cgcatacatg      540

ccctacgtca agaaggcact ggaggaccgt ggcattgtgg aactgctcct gacttcagac      600

aacaaggatg ggctgagcaa ggggattgtc cagggagtct tggccaccat caacttgcag      660

tcaacacacg agctgcagct actgaccacc tttctcttca acgtccaggg gactcagccc      720

aagatggtga tggagtactg gacggggtgg tttgactcgt ggggaggccc tcacaatatc      780

ttggattctt ctgaggtttt gaaaaccgtg tctgccattg tggacgccgg ctcctccatc      840

aacctctaca tgttccacgg aggcaccaac tttggcttca tgaatggagc catgcacttc      900

catgactaca agtcagatgt caccagctat gactatgatg ctgtgctgac agaagccggc      960

gattacacgg ccaagtacat gaagcttcga gacttcttcg gctccatctc aggcatccct     1020

ctccctcccc cacctgacct tcttcccaag atgccgtatg agcccttaac gccagtcttg     1080

tacctgtctc tgtgggacgc cctcaagtac ctgggggagc caatcaagtc tgaaaagccc     1140

atcaacatgg agaacctgcc agtcaatggg ggaaatggac agtccttcgg gtacattctc     1200

tatgagacca gcatcacctc gtctggcatc ctcagtggcc acgtgcatga tcgggggcag     1260

gtgtttgtga acacagtatc cataggattc ttggactaca agacaacgaa gattgctgtc     1320

cccctgatcc agggttacac cgtgctgagg atcttggtgg agaatcgtgg gcgagtcaac     1380

tatggggaga atattgatga ccagcgcaaa ggcttaattg gaaatctcta tctgaatgat     1440

tcacccctga aaaacttcag aatctatagc ctggatatga agaagagctt ctttcagagg     1500

ttcggcctgg acaaatggag ttccctccca gaaacaccca cattacctgc tttcttcttg     1560

ggtagcttgt ccatcagctc caccccttgt gacacctttc tgaagctgga gggctgggag     1620

aagggggttg tattcatcaa tggccagaac cttggacgtt actggaacat tggaccccag     1680

aagacgcttt acctcccagg tccctggttg agcagcggaa tcaaccaggt catcgttttt     1740

gaggagacga tggcgggccc tgcattacag ttcacggaaa ccccccacct gggcaggaac     1800

cagtacatta ag                                                         1812


<210>  5723
<211>  1974
<212>  DNA
<213>  Homo Sapiens

<400>  5723
gtgcccccgc gccgggacta ctgcgtgctg ggcgctgggc ccgcgggcct gcagatggcc       60

tacttcctgc agcgcgctgg acgcgactac gcagtgttcg agcgggcccc gcggcccggc      120

agcttcttca cacgctaccc gcggcaccgc aagctcatca gcatcaacaa gcggtacacg      180

ggcaaggcta acgccgagtt caacctccgc cacgactgga actctctgct cagccacgac      240

ccccggctgc tcttcagaca ctactcgcgt gcctacttcc ccgacgcccg cgacatggtg      300

cgctacctgg gtgacttcgc ggacacgctg gggctccgtg tccagtacaa caccaccatc      360

gcccacgtca ctctggacaa ggaccgacag gcctggaatg gccactactt catcctaact      420

gaccagaagg gccaggtgca tcagtgcagc gtcctctttg tagccactgg tttatcagtc      480

cccaaccagg ttgacttccc tggctccgaa tatgcagagg gttacgagtc cgtgtccgtg      540

gaccctgagg actttgtagg ccagaatgtg ctgatcctgg gtcgtgggaa ctcggccttt      600

gagacagcag agaacatctt gggtgtcaca aactttatcc atatgctcag ccgctcccgg      660

gtccgtctgt cctgggccac ccactacgtt ggagacctca gagccatcaa caatggcctg      720

ctggatacct accagctcaa gtccctggac gggctgctcg agtctgacct gacggatctg      780

gccatcctga aggacagcaa aggcaagttc catgtcaccc cgaaattctt cctggaagaa      840

gccaacacca accagagtgc cgactccatc accctccccc aggacgacaa tgacaacttt      900

gccatgcgcg tgccctatga ccgggtaatc cgctgcctgg gctggaactt tgacttctcc      960

attttcaata agtccctcag acttaactcg ggaaatgcat tcggcaagaa gtacccgctg     1020

attcgagcta gctacgaatc caaaggaagc cggggtctgt ttatcctggg tactgccagc     1080

cactcggtgg actaccggaa atctgctggg ggcttcatcc acggattccg atacacagtg     1140

cgtgctgttc accggctcct ggagcaccgc caccacagcg tcacctggcc cgccactgag     1200

ctccccatca cacagctgac cagctccatc gtgcggcgcg tgaatgaggc ttctgggctc     1260

taccagatgt tcggtgtgct ggccgatgtc atcctgttga aggagaattc cacggccttt     1320

gagtacctgg aggagttccc catacagatg ctggcccagc tggagacact cacagggagg     1380

aaggcaaagc acgggctctt cgtcatcaac atggaatatg gcagaaattt ctctggcccc     1440

gacaaggacg tcttctttga tgaccggtct gtggggcaca cagaagatgc ctggcagtct     1500

aactttcttc atcctgtcat ctactactat agatacctcc ccaccgaaca ggaggtgagg     1560

ttccgccctg cacactggcc cctgcctcgg cccacggcca tccatcacat cgtggaagac     1620

ttcttaacag actggactgc cccgatcggg cacatcctac ctctgaggcg cttcctggag     1680

aactgtttgg acaccgattt gcgaagcttc tatgcagagt cctgcttcct gttcgccctc     1740

acgcgccaga agttgccacc cttttgccag caggggtacc tgaggatgca gggactcgtg     1800

agtaccgaga gcctttggca gcacagagtg gagagcaggc tcctgcggga ctatgccccc     1860

acaggcaggc gcctggagga cagcagccag cagcttggcg accaagagcc actaggttcc     1920

cccctggctc cagggcctct ggctcagtcc gtcgatagca acaaagagga gctc           1974


<210>  5724
<211>  2538
<212>  DNA
<213>  Homo Sapiens

<400>  5724
ttcctgtcgc accaccgcct gaaaggcagg tttcagaggg accgcaggaa catccgcccc       60

aacatcatcc tggtgctgac ggacgaccag gatgtggagc tgggttccat gcaggtgatg      120

aacaagaccc ggcgcatcat ggagcagggc ggggcgcact tcatcaacgc cttcgtgacc      180

acacccatgt gctgcccctc acgctcctcc atcctcaccg gcaagtacgt ccacaaccac      240

aacacctaca ccaacaatga gaactgctcc tcgccctcct ggcaggcaca gcacgagagc      300

cgcacctttg ccgtgtacct caatagcact ggctaccgga cagctttctt cgggaagtat      360

cttaatgaat acaacggctc ctacgtgcca cccggctgga aggagtgggt cggactcctt      420

aaaaactccc gcttttataa ctacacgctg tgtcggaacg gggtgaaaga gaagcacggc      480

tccgactact ccaaggatta cctcacagac ctcatcacca atgacagcgt gagcttcttc      540

cgcacgtcca agaagatgta cccgcacagg ccagtcctca tggtcatcag ccatgcagcc      600

ccccacggcc ctgaggattc agccccacaa tattcacgcc tcttcccaaa cgcatctcag      660

cacatcacgc cgagctacaa ctacgcgccc aacccggaca aacactggat catgcgctac      720

acggggccca tgaagcccat ccacatggaa ttcaccaaca tgctccagcg gaagcgcttg      780

cagaccctca tgtcggtgga cgactccatg gagacgattt acaacatgct ggttgagacg      840

ggcgagctgg acaacacgta catcgtatac accgccgacc acggttacca catcggccag      900

tttggcctgg tgaaagggaa atccatgcca tatgagtttg acatcagggt cccgttctac      960

gtgaggggcc ccaacgtgga agccggctgt ctgaatcccc acatcgtcct caacattgac     1020

ctggccccca ccatcctgga cattgcaggc ctggacatac ctgcggatat ggacgggaaa     1080

tccatcctca agctgctgga cacggagcgg ccggtgaatc ggtttcactt gaaaaagaag     1140

atgagggtct ggcgggactc cttcttggtg gagagaggca agctgctaca caagagagac     1200

aatgacaagg tggacgccca ggaggagaac tttctgccca agtaccagcg tgtgaaggac     1260

ctgtgtcagc gtgctgagta ccagacggcg tgtgagcagc tgggacagaa gtggcagtgt     1320

gtggaggacg ccacggggaa gctgaagctg cataagtgca agggccccat gcggctgggc     1380

ggcagcagag ccctctccaa cctcgtgccc aagtactacg ggcagggcag cgaggcctgc     1440

acctgtgaca gcggggacta caagctcagc ctggccggac gccggaaaaa actcttcaag     1500

aagaagtaca aggccagcta tgtccgcagt cgctccatcc gctcagtggc catcgaggtg     1560

gacggcaggg tgtaccacgt aggcctgggt gatgccgccc agccccgaaa cctcaccaag     1620

cggcactggc caggggcccc tgaggaccaa gatgacaagg atggtgggga cttcagtggc     1680

actggaggcc ttcccgacta ctcagccgcc aaccccatta aagtgacaca tcggtgctac     1740

atcctagaga acgacacagt ccagtgtgac ctggacctgt acaagtccct gcaggcctgg     1800

aaagaccaca agctgcacat cgaccacgag attgaaaccc tgcagaacaa aattaagaac     1860

ctgagggaag tccgaggtca cctgaagaaa aagcggccag aagaatgtga ctgtcacaaa     1920

atcagctacc acacccagca caaaggccgc ctcaagcaca gaggctccag tctgcatcct     1980

ttcaggaagg gcctgcaaga gaaggacaag gtgtggctgt tgcgggagca gaagcgcaag     2040

aagaaactcc gcaagctgct caagcgcctg cagaacaacg acacgtgcag catgccaggc     2100

ctcacgtgct tcacccacga caaccagcac tggcagacgg cgcctttctg gacactgggg     2160

cctttctgtg cctgcaccag cgccaacaat aacacgtact ggtgcatgag gaccatcaat     2220

gagactcaca atttcctctt ctgtgaattt gcaactggct tcctagagta ctttgatctc     2280

aacacagacc cctaccagct gatgaatgca gtgaacacac tggacaggga tgtcctcaac     2340

cagctacacg tacagctcat ggagctgagg agctgcaagg gttacaagca gtgtaacccc     2400

cggactcgaa acatggacct gggacttaaa gatggaggaa gctatgagca atacaggcag     2460

tttcagcgtc gaaagtggcc agaaatgaag agaccttctt ccaaatcact gggacaactg     2520

tgggaaggct gggaaggt                                                   2538


<210>  5725
<211>  2547
<212>  DNA
<213>  Homo Sapiens

<400>  5725
tcgactgtca gatccccgag gttcagagga cggatacagc aggaacgaaa aaacatccga       60

cccaacatta ttcttgtgct taccgatgat caagatgtgg agctggggtc cctgcaagtc      120

atgaacaaaa cgagaaagat tatggaacat gggggggcca ccttcatcaa tgcctttgtg      180

actacaccca tgtgctgccc gtcacggtcc tccatgctca ccgggaagta tgtgcacaat      240

cacaatgtct acaccaacaa cgagaactgc tcttccccct cgtggcaggc catgcatgag      300

cctcggactt ttgctgtata tcttaacaac actggctaca gaacagtctt ttttggaaaa      360

tacctcaatg aatataatgg cagctacatc ccccctgggt ggcgagaatg gcttggatta      420

atcaagaatt ctcgcttcta taattacact gtttgtcgca atggcatcaa agaaaagcat      480

ggatttgatt atgcaaagga ctacttcaca gacttaatca ctaacgagag cattaattac      540

ttcaaaatgt ctaagagaat gtatccccat aggcccgtta tgatggtgat cagccacgct      600

gcgccccacg gccccgagga ctcagcccca cagttttcta aactgtaccc caatgcttcc      660

caacacataa ctcctagtta taactatgca ccaaatatgg ataaacactg gattatgcag      720

tacacaggac caatgctgcc catccacatg gaatttacaa acattctaca gcgcaaaagg      780

ctccagactt tgatgtcagt ggatgattct gtggagaggc tgtataacat gctcgtggag      840

acgggggagc tggagaatac ttacatcatt tacaccgccg accatggtta ccatattggg      900

cagtttggac tggtcaaggg gaaatccatg ccatatgact ttgatattcg tgtgcctttt      960

tttattcgtg gtccaagtgt agaaccagga tcaatagtcc cacagatcgt tctcaacatt     1020

gacttggccc ccacgatcct ggatattgct gggctcgaca cacctcctga tgtggacggc     1080

aagtctgtcc tcaaacttct ggacccagaa aagccaggta acaggtttcg aacaaacaag     1140

aaggccaaaa tttggcgtga tacattccta gtggaaagag gcaaatttct acgtaagaag     1200

gaagaatcca gcaagaatat ccaacagtca aatcacttgc ccaaatatga acgggtcaaa     1260

gaactatgcc agcaggccag gtaccagaca gcctgtgaac aaccggggca gaagtggcaa     1320

tgcattgagg atacatctgg caagcttcga attcacaagt gtaaaggacc cagtgacctg     1380

ctcacagtcc ggcagagcac gcggaacctc tacgctcgcg gcttccatga caaagacaaa     1440

gagtgcagtt gtagggagtc tggttaccgt gccagcagaa gccaaagaaa gagtcaacgg     1500

caattcttga gaaaccaggg gactccaaag tacaagccca gatttgtcca tactcggcag     1560

acacgttcct tgtccgtcga atttgaaggt gaaatatatg acataaatct ggaagaagaa     1620

gaagaattgc aagtgttgca accaagaaac attgccaagc gtcatgatga aggccacaag     1680

gggccaagag atctccaggc ttccagtggt ggcaacaggg gcaggatgct ggcagatagc     1740

agcaacgccg tgggcccacc taccactgtc cgagtgacac acaagtgttt tattcttccc     1800

aatgactcta tccattgtga gagagaactg taccaatcgg ccagagcgtg gaaggaccat     1860

aaggcataca ttgacaaaga gattgaagct ctgcaagata aaattaagaa tttaagagaa     1920

gtgagaggac atctgaagag aaggaagcct gaggaatgta gctgcagtaa acaaagctat     1980

tacaataaag agaaaggtgt aaaaaagcaa gagaaattaa agagccatct tcacccattc     2040

aaggaggctg ctcaggaagt agatagcaaa ctgcaacttt tcaaggagaa caaccgtagg     2100

aggaagaagg agaggaagga gaagagacgg cagaggaagg gggaagagtg cagcctgcct     2160

ggcctcactt gcttcacgca tgacaacaac cactggcaga cagccccgtt ctggaacctg     2220

ggatctttct gtgcttgcac gagttctaac aataacacct actggtgttt gcgtacagtt     2280

aatgagacgc ataattttct tttctgtgag tttgctactg gctttttgga gtattttgat     2340

atgaatacag atccttatca gctcacaaat acagtgcaca cggtagaacg aggcattttg     2400

aatcagctac acgtacaact aatggagctc agaagctgtc aaggatataa gcagtgcaac     2460

ccaagaccta agaatcttga tgttggaaat aaagatggag gaagctatga cctacacaga     2520

ggacagttat gggatggatg ggaaggt                                         2547


<210>  5726
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  5726
aagaatgctg agatgtccaa ggagctgctg ggctttaaaa gggagctttg gaatgtctca       60

aactccgtac aagcatgcga agagagacag aagagaggct gggattccgt tcagcagagc      120

atcaccatgg tcaggagcaa gattgataga ttagagacga cattagcagg cataaaaaac      180

attgacacaa aggtacagaa aatcttggag gtgctgcaga aaatgccaca gtcctcacct      240

caa                                                                    243


<210>  5727
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  5727
agtgaggcca agctctacgg tcgttgtgaa ctggccagag tgctacatga cttcgggctg       60

gacggatacc ggggatacag cctggctgac tgggtctgcc ttgcttattt cacaagcggt      120

ttcaacgcag ctgctttgga ctacgaggct gatgggagca ccaacaacgg gatcttccag      180

atcaacagcc ggaggtggtg cagcaacctc accccgaacg tccccaacgt gtgccggatg      240

tactgctcag atttgttgaa tcctaatctc aaggataccg ttatctgtgc catgaagata      300

acccaagagc ctcagggtct gggttactgg gaggcctgga ggcatcactg ccagggaaaa      360

gacctcactg aatgggtgga tggctgtgac ttc                                   393


<210>  5728
<211>  2283
<212>  DNA
<213>  Homo Sapiens

<400>  5728
gatcaggatt tttacagttt acttggagtg tccaaaactg caagcagtag agaaataaga       60

caagctttca agaaattggc attgaagtta catcctgata aaaacccgaa taacccaaat      120

gcacatggcg attttttaaa aataaataga gcatatgaag tactcaaaga tgaagatcta      180

cggaaaaagt atgacaaata tggagaaaag ggacttgagg ataatcaagg tggccagtat      240

gaaagctgga actattatcg ttatgatttt ggtatttatg atgatgatcc tgaaatcata      300

acattggaaa gaagagaatt tgatgctgct gttaattctg gagaactgtg gtttgtaaat      360

ttttactccc caggctgttc acactgccat gatttagctc ccacatggag agactttgct      420

aaagaagtgg atgggttact tcgaattgga gctgttaact gtggtgatga tagaatgctt      480

tgccgaatga aaggagtcaa cagctatccc agcctcttca tttttcggtc tggaatggcc      540

ccagtgaaat atcatggaga cagatcaaag gagagtttag tgagttttgc aatgcagcat      600

gttagaagta cagtgacaga actttggaca ggaaattttg tcaactccat acaaactgct      660

tttgctgctg gtattggctg gctgatcact ttttgttcaa aaggaggaga ttgtttgact      720

tcacagacac gactcaggct tagtggcatg ttggatggtc ttgttaatgt aggatggatg      780

gactgtgcca cccaggataa cctttgtaaa agcttagata ttacaacaag tactactgct      840

tattttcctc ctggagccac tttaaataac aaagagaaaa acagtatttt gtttctcaac      900

tcattggatg ctaaagaaat atatttggaa gtaatacata atcttccaga ttttgaacta      960

ctttcggcaa acacactaga ggatcgtttg gctcatcatc ggtggctgtt attttttcat     1020

tttggaaaaa atgaaaattc aaatgatcct gagctgaaaa aactaaaaac tctacttaaa     1080

aatgatcata ttcaagttgg caggtttgac tgttcctctg caccagacat ctgtagtaat     1140

ctgtatgttt ttcagccgtc tctagcagta tttaaaggac aaggaaccaa agaatatgaa     1200

attcatcatg gaaagaagat tctatatgat atacttgcct ttgccaaaga aagtgtgaat     1260

tctcatgtta ccacgcttgg acctcaaaat tttcctgcca atgacaaaga accatggctt     1320

gttgatttct ttgccccctg gtgtccacca tgtcgagctt tactaccaga gttacgaaga     1380

gcatcaaatc ttctttatgg tcagcttaag tttggtacac tagattgtac agttcatgag     1440

ggactctgta acatgtataa cattcaggct tatccaacaa cagtggtatt caaccagtcc     1500

aacattcatg agtatgaagg acatcactct gctgaacaaa tcttggagtt catagaggat     1560

cttatgaatc cttcagtggt ctcccttaca cccaccacct tcaacgaact agttacacaa     1620

agaaaacaca acgaagtctg gatggttgat ttctattctc cgtggtgtca tccttgccaa     1680

gtcttaatgc cagaatggaa aagaatggcc cggacattaa ctggactgat caacgtgggc     1740

agtatagatt gccaacagta tcattctttt tgtgcccagg aaaacgttca aagataccct     1800

gagataagat tttttccccc aaaatcaaat aaagcttatc agtatcacag ttacaatggt     1860

tggaataggg atgcttattc cctgagaatc tggggtctag gatttttacc tcaagtatcc     1920

acagatctaa cacctcagac tttcagtgaa aaagttctac aagggaaaaa tcattgggtg     1980

attgatttct atgctccttg gtgtggacct tgccagaatt ttgctccaga atttgagctc     2040

ttggctagga tgattaaagg aaaagtgaaa gctggaaaag tagactgtca ggcttatgct     2100

cagacatgcc agaaagctgg gatcagggcc tatccaactg ttaagtttta tttctacgaa     2160

agagcaaaga gaaattttca agaagagcag ataaatacca gagatgcaaa agcaatcgct     2220

gccttaataa gtgaaaaatt ggaaactctc cgaaatcaag gcaagaggaa taaggatgaa     2280

ctt                                                                   2283


<210>  5729
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  5729
atggcccacc cggtgcagtc cgagtttcct tcagcacagg agtcaggctc cgccgcatcc       60

ctggacctgc cagagatgga gatactcctc accaaggcag agaacaagga tgacaagacc      120

ctgaatctgt ccaagaccct ctcggggcct ctggatctgg agcagaacgg ccagggccta      180

cccttcaagg ccatctccga ggggcacctg gaggccccac tgcctcggtc cccctcccgg      240

gccagctcaa ggagggcgtc ctccatcgcc accacctcct atgcccaaga ccaagaagcc      300

cccagagatt acctc                                                       315


<210>  5730
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  5730
tcttcatcct cccctcgaac cccaccagcc ccagcccgcc ccccgtgtgc caggggaggc       60

ccctcggccc cacgtcatgt gtgcgtgtgg gagcgagcac ctccaccaag ccgatctcct      120

cgggtcccaa gatcacgtcg gcaagtcctg cctggcactg cacccccagc caccccatca      180

ggctttgagg aggggccgcc ctcatcccaa tacccctggg ctatcgtgtg gggtcccacc      240

gtgtctcgag aggatggagg ggaccccaac tctgccaatc ccggatttct ggactatggt      300

tttgcagccc ctcatgggct cgcaacccca caccccaact cagactccat gcgaggtgat      360

ggagatgggc ttatccttgg agaggcacct gccaccctgc ggccattcct gttcgggggc      420

cgtggggaag gtgtggaccc c                                                441


<210>  5731
<211>  1797
<212>  DNA
<213>  Homo Sapiens

<400>  5731
cgcttcgtcg ccgagcggga ctcggaggac gacggagagg agccggtggt tttcccggag       60

tcgcccctgc agagccccac ggtgctcgtg gcggtcctcg cccgcaacgc ggcgcacacg      120

ctgccgcact tcctcggctg cctggagcgg ctggactacc ccaagagcag gatggccatc      180

tgggcagcca ctgatcacaa tgtggataat acaacagaaa tattcaggga gtggttgaaa      240

aatgtacaga gactctatca ctatgtggag tggaggccta tggatgaacc agagtcttac      300

cctgatgaaa ttggaccaaa gcactggcca acctcccggt ttgcccatgt gatgaaacta      360

cgacaggcag cccttcgaac tgcgagggaa aaatggtcag actacattct gttcatagat      420

gttgacaatt tcctgactaa tccacagacc ctcaatctac tgattgcaga aaacaaaact      480

attgtggccc ccatgctgga gtctcggggc ctgtattcta atttctggtg cggaatcacc      540

cctaagggct tctataagag gaccccagac tacgttcaga ttcgagaatg gaagaggaca      600

ggctgcttcc ccgtccccat ggtccactcc accttcctaa ttgacctcag gaaggaggcc      660

tcggacaagc tgactttcta ccccccacac caggactaca cctggacctt tgatgacatc      720

attgtctttg ccttctccag caggcaagca ggcatccaga tgtacctctg caacagagag      780

cactatggct acctgcccat ccccctgaag ccccatcaga cactgcagga agacatcgag      840

aacctcatcc atgtgcagat tgaagcaatg attgaccgtc ctccaatgga accctcccag      900

tatgtctcag ttgtccctaa atatccagac aagatgggat ttgatgagat tttcatgata      960

aacctcaaac gcagaaagga caggcgggac cggatgctgc gcacactgta tgaacaggag     1020

attgaggtca agattgtcga ggctgtggat ggaaaggcac tcaacacaag ccagctgaag     1080

gcactgaata ttgaaatgct gcctggctat cgagatccct attcctccag gcctctaaca     1140

aggggtgaaa tcggctgctt tctcagccac tactcagtct ggaaagaggt aattgatcga     1200

gagctagaga agactcttgt aattgaagac gatgtgcgtt ttgagcatca gtttaagaag     1260

aagctgatga agctgatgga taacattgac caggctcagc tggactggga actgatttat     1320

attggtagga agaggatgca agtaaaggag ccagagaaag cagtgcccaa tgtggcaaac     1380

ctggtcgaag ccgactattc ctactggacc ctgggctacg tcatctctct ggaaggagca     1440

cagaagctgg ttggagccaa tccttttggg aagatgctgc cagtggatga gtttctgcca     1500

gtcatgtaca acaagcatcc cgtagccgag tacaaggagt attatgaatc cagggacctg     1560

aaagccttct ctgcagaacc cttgctcatc taccctacgc actacacagg ccagccgggg     1620

tacctgagtg acacggagac ctccaccatc tgggacaatg agacagtggc caccgactgg     1680

gataggacac atgcctggaa gtcccggaag caaagccgca tctacagcaa tgccaagaac     1740

acagaggccc tgccaccgcc aacctccctg gacactgtgc cttcaaggga tgagcta        1797


<210>  5732
<211>  1647
<212>  DNA
<213>  Homo Sapiens

<400>  5732
cggcgggcgg cgggcggcct gcacctgctg ccctggtccc gcggtgagcc gggcgccgcc       60

gagccgtctg cctgcctgga ggcggccacc cgcgcctggc gcggcctgcg ggagcgcggt      120

gaggtggtac cgctgggtcc tggagtgccg gccctggtgg ccaacggctt cctggcactg      180

gacgtggctg ccaatcggct gtgggtgact cccggggagc gggagcccgc cgtggcgccg      240

gactttgtgc ccttcgtgca gctgcgcccg ctgagcgcgc tggctgaagc tggagaggcg      300

gtgctgctgc tgcgggaggg gcttctgcgc cgcgtgcgtt gcctgcagct ggggtcccca      360

ggtcctggcc ccgtggccgc cggccccggg cccgcctccg tctctggcct tgccgcgggg      420

tccggccgcg actgcgtgct gctgcaagag gactttctgg cgcacagggg ccgaccccac      480

gtctacctgc agcgcatcca gctcaacaac cccacggagc gcgtggccgc gctgcagact      540

gtggggccca ctgccggccc agcccccaag gccttcacca gtaccctgga gaaggtcgga      600

gaccatcagt tcctcctcta ctcaggccgg tccccgccta cgcccactgg gttggtgcac      660

ctggtggtgg tggccgccaa gaagctggtg aaccgcctcc aagtggctcc caagacgcag      720

ctggatgaga cggtgctgtg ggtggtgcac gtctctggcc ccattaaccc ccaggtgctc      780

aaaagcaaag cagccaagga gctcaaggcg ctgcaggact tggcacggaa ggaaatgctg      840

gagctcttgg acatgccagc ggcggagctg cttcaagacc accagctcct ctgggctcag      900

ctcttcagcc caggagtgga aatgaagaag atcactgaca cccacacgcc gtctggcctc      960

accgtgaacc tgacgctcta ttacatgctc tcctgctcgc cagccccact gctcagcccc     1020

tccctgagcc acagggagcg agaccagatg gagtcgacgc tcaactatga agatcactgc     1080

ttcagcgggc acgccaccat gcacgccgag aacctgtggc cggggcggct gtcctccgtc     1140

cagcagatcc tgcagctctc tgacctgtgg aggctgaccc tccagaagcg tggctgcaag     1200

gggctggtga aggtgggtgc cccaggcatc ctgcagggga tggtgctcag ctttgggggg     1260

ctgcagttca cagagaacca cctccagttc caggccgacc ccgacgtgct gcacaacagc     1320

tatgcattgc atggcatccg ctacaagaac gaccatatca acctggccgt gctggcggat     1380

gccgagggca agccctacct acacgtgtcc gtggagtccc gtggccagcc tgtcaagatc     1440

tatgcctgca aggcaggctg cctggacgag ccagtggagc tgacctcggc gcccacgggc     1500

cacaccttct cggtcatggt gacacagccc atcacgccac tgctctacat ctccaccgac     1560

ctcacacacc tgcaggacct gcggcacacg ctgcacctca aggccatcct ggcccatgat     1620

gagcacatgg cccagcagga ccccggg                                         1647


<210>  5733
<211>  3120
<212>  DNA
<213>  Homo Sapiens

<400>  5733
gacgtggtgc gctcggagca gcagataccg ctctccgtgg tgaagctctg ggcctcggct       60

tttggtgggg agataaaatc cattgctgct aagtactccg gttcccagct tctgcaaaag      120

aaatacaaag agtatgagaa agacgttgcc atagaagaaa ttgatggcct ccaactggta      180

aagaagctgg caaagaacat ggaagagatg tttcacaaga agtctgaggc cgtcaggcgt      240

ctggtggagg ctgcagaaga agcacacctg aaacatgaat ttgatgcaga cttacagtat      300

gaatacttca atgctgtgct gataaatgaa agggacaaag acgggaattt tttggagctg      360

ggaaaggaat tcatcttagc cccaaatgac cattttaata atttgcctgt gaacatcagt      420

ctaagtgacg tccaagtacc aacgaacatg tacaacaaag accctgcaat tgtcaatggg      480

gtttattggt ctgaatctct aaacaaagtt tttgtagata actttgaccg tgacccatct      540

ctcatatggc agtactttgg aagtgcaaag ggctttttta ggcagtatcc ggggattaaa      600

tgggaaccag atgagaatgg agtcattgcc ttcgactgca ggaaccgaaa atggtacatc      660

caggcagcaa cttctccgaa agacgtggtc attttagttg acgtcagtgg cagcatgaaa      720

ggactccgtc tgactatcgc gaagcaaaca gtctcatcca ttttggatac acttggggat      780

gatgacttct tcaacataat tgcttataat gaggagcttc actatgtgga accttgcctg      840

aatggaactt tggtgcaagc cgacaggaca aacaaagagc acttcaggga gcatctggac      900

aaacttttcg ccaaaggaat tggaatgttg gatatagctc tgaatgaggc cttcaacatt      960

ctgagtgatt tcaaccacac gggacaagga agtatctgca gtcaggccat catgctcata     1020

actgatgggg cggtggacac ctatgataca atctttgcaa aatacaattg gccagatcga     1080

aaggttcgca tcttcacata cctcattgga cgagaggctg cgtttgcaga caatctaaag     1140

tggatggcct gtgccaacaa aggatttttt acccagatct ccaccttggc tgatgtgcag     1200

gagaatgtca tggaatacct tcacgtgctt agccggccca aagtcatcga ccaggagcat     1260

gatgtggtgt ggaccgaagc ttacattgac agcactctcc ctcaggcaca aaagctgact     1320

gatgatcagg gccccgtcct gatgaccact gtagccatgc ctgtgtttag taagcagaac     1380

gaaaccagat cgaagggcat tcttctggga gtggttggca cagatgtccc agtgaaagaa     1440

cttctgaaga ccatccccaa atacaagtta gggattcacg gttatgcctt tgcaatcaca     1500

aataatggat atatcctgac gcatccggaa ctcaggctgc tgtacgaaga aggaaaaaag     1560

cgaaggaaac ctaactatag tagcgttgac ctctctgagg tggagtggga agaccgagat     1620

gacgtgttga gaaatgctat ggtgaatcga aagacgggga agttttccat ggaggtgaag     1680

aagacagtgg acaaagggaa acgggttttg gtgatgacaa atgactacta ttatacagac     1740

atcaagggta ctcctttcag tttaggtgtg gcgctttcca gaggtcatgg gaaatatttc     1800

ttccgaggga atgtaaccat cgaagaaggc ctgcatgact tagaacatcc cgatgtgtcc     1860

ttggcagatg aatggtccta ctgcaacact gacctacacc ctgagcaccg ccatctgtct     1920

cagttagaag cgattaagct ctacctaaaa ggcaaagaac ctctgctcca gtgtgataaa     1980

gaattgatcc aagaagtcct ttttgacgcg gtggtgagtg cccccattga agcgtattgg     2040

accagcctgg ccctcaacaa atctgaaaat tctgacaagg gcgtggaggt tgccttcctc     2100

ggcactcgca cgggcctctc cagaatcaac ctgtttgtcg gggctgagca gctcaccaat     2160

caggacttcc tgaaagctgg tgacaaggag aacattttta acgcagacca tttccctctc     2220

tggtaccgaa gagccgctga gcagattcca gggagcttcg tctactcgat cccattcagc     2280

actggaccag tcaataaaag caatgtggtg acagcaagta catccatcca gctcctggat     2340

gaacggaaat ctcctgtggt ggcagctgta ggcattcaga tgaaacttga atttttccaa     2400

aggaagttct ggactgccag cagacagtgt gcttccctgg atggcaaatg ctccatcagc     2460

tgtgatgatg agactgtgaa ttgttacctc atagacaata atggatttat tttggtgtct     2520

gaagactaca cacagactgg agactttttt ggtgagatcg agggagctgt gatgaacaaa     2580

ttgctaacaa tgggctcctt taaaagaatt accctttatg actaccaagc catgtgtaga     2640

gccaacaagg aaagcagcga tggcgcccat ggcctcctgg atccttataa tgccttcctc     2700

tctgcagtaa aatggatcat gacagaactt gtcttgttcc tggtggaatt taacctctgc     2760

agttggtggc actccgatat gacagctaaa gcccagaaat tgaaacagac cctggagcct     2820

tgtgatactg aatatccagc attcgtctct gagcgcacca tcaaggagac tacagggaat     2880

attgcttgtg aagactgctc caagtccttt gtcatccagc aaatcccaag cagcaacctg     2940

ttcatggtgg tggtggacag cagctgcctc tgtgaatctg tggcccccat caccatggca     3000

cccattgaaa tcaggtataa tgaatccctt aagtgtgaac gtctaaaggc ccagaagatc     3060

agaaggcgcc cagaatcttg tcatggcttc catcctgagg agaatgcaag ggagtgtggg     3120


<210>  5734
<211>  1398
<212>  DNA
<213>  Homo Sapiens

<400>  5734
ctccttcatc cagacagcag gtctcatcct aggtccttag agaaaagtgc ctggagggct       60

tttaaggagt cacagtgcca tcacatgctc aaacatctcc acaatggtgc aaggatcaca      120

gtgcagatgc cacctacaat cgagggccac tgggtctcca caggctgtga agtaaggtca      180

ggcccagagt tcatcacaag gtcctacaga ttctaccaca ataacacctt caaggcctac      240

caattttatt atggcagcaa ccggtgcaca aatcccactt atactctcat catccggggc      300

aagatccgcc tccgccaggc ctcctggatc atccgagggg gcacggaagc cgactaccag      360

ctgcacaacg tccaggtgat ctgccacaca gaggcggtgg ccgagaagct cggccagcag      420

gtgaaccgca catgcccggg cttcctcgca gacgggggtc cctgggtgca ggacgtggcc      480

tatgacctct ggcgagagga gaacggctgt gagtgcacca aggccgtgaa ctttgccatg      540

catgaacttc agctcatccg ggtggagaag cagtaccttc accacaacct cgaccacctg      600

gtcgaggagc tcttccttgg tgacattcac actgatgcca cccagaggat gttctaccgg      660

ccctccagtt accagccccc tctgcagaat gccaagaacc acgaccatgc ctgcatcgcc      720

tgtcggatca tctatcggtc agacgagcac caccctccca tcctgccccc aaaggcagac      780

ctgaccatcg gcctgcacgg ggagtgggtg agccagcgct gtgaggtgcg ccccgaagtc      840

ctcttcctca cccgccactt catcttccat gacaacaaca acacctggga gggccactac      900

taccactact cagacccggt gtgcaagcac cccaccttct ccatctacgc ccggggccgc      960

tacagccgcg gcgtcctctc gtccagggtc atgggaggca ccgagttcgt gttcaaagtg     1020

aatcacatga aggtcacccc catggatgcg gccacagcct cactgctcaa cgtcttcaac     1080

gggaatgagt gcggggccga gggctcctgg caggtgggca tccagcagga tgtgacccac     1140

accaatggct gcgtggccct gggcatcaaa ctacctcaca cggagtacga gatcttcaaa     1200

atggaacagg atgcccgggg gcgctatctg ctgttcaacg gtcagaggcc cagcgacggg     1260

tccagcccag acaggccaga gaagagagcc acgtcctacc agatgccctt ggtccagtgt     1320

gcctcctctt cgccgagggc agaggacctc gcagaagaca gtggaagcag cctgtatggc     1380

cgggcccctg ggaggcac                                                   1398


<210>  5735
<211>  1905
<212>  DNA
<213>  Homo Sapiens

<400>  5735
caagcacagt atccagttgt caacacaaat tatggcaaaa tccggggcct aagaacaccg       60

ttacccaatg agatcttggg tccagtggag cagtacttag gggtccccta tgcctcaccc      120

cccactggag agaggcggtt tcagccccca gaacccccgt cctcctggac tggcatccga      180

aatactactc agtttgctgc tgtgtgcccc cagcacctgg atgagagatc cttactgcat      240

gacatgctgc ccatctggtt taccgccaat ttggatactt tgatgaccta tgttcaagat      300

caaaatgaag actgccttta cttaaacatc tacgtgccca cggaagatga tattcatgat      360

cagaacagta agaagcccgt catggtctat atccatgggg gatcttacat ggagggcacc      420

ggcaacatga ttgacggcag cattttggca agctacggaa acgtcattgt gatcaccatt      480

aactaccgtc tgggaatact agggttttta agtaccggtg accaggcagc aaaaggcaac      540

tatgggctcc tggatcagat tcaagcactg cggtggattg aggagaatgt gggagccttt      600

ggcggggacc ccaagagagt gaccatcttt ggctcggggg ctggggcctc ctgtgtcagc      660

ctgttgaccc tgtcccacta ctcagaaggt ctcttccaga aggccatcat tcagagcggc      720

accgccctgt ccagctgggc agtgaactac cagccggcca agtacactcg gatattggca      780

gacaaggtcg gctgcaacat gctggacacc acggacatgg tagaatgcct gcggaacaag      840

aactacaagg agctcatcca gcagaccatc accccggcca cctaccacat agccttcggg      900

ccggtgatcg acggcgacgt catcccagac gacccccaga tcctgatgga gcaaggcgag      960

ttcctcaact acgacatcat gctgggcgtc aaccaagggg aaggcctgaa gttcgtggac     1020

ggcatcgtgg ataacgagga cggtgtgacg cccaacgact ttgacttctc cgtgtccaac     1080

ttcgtggaca acctttacgg ctaccctgaa gggaaagaca ctttgcggga gactatcaag     1140

ttcatgtaca cagactgggc cgataaggaa aacccggaga cgcggcggaa aaccctggtg     1200

gctctcttta ctgaccacca gtgggtggcc cccgccgtgg ccaccgccga cctgcacgcg     1260

cagtacggct cccccaccta cttctatgcc ttctatcatc actgccaaag cgaaatgaag     1320

cccagctggg cagattcggc ccatggtgat gaggtcccct atgtcttcgg catccccatg     1380

atcggtccca ccgagctctt cagttgtaac ttttccaaga acgacgtcat gctcagcgcc     1440

gtggtcatga cctactggac gaacttcgcc aaaactggtg atccaaatca accagttcct     1500

caggatacca agttcattca cacaaaaccc aaccgctttg aagaagtggc ctggtccaag     1560

tataatccca aagaccagct ctatctgcat attggcttga aacccagagt gagagatcac     1620

taccgggcaa cgaaagtggc tttctggttg gaactcgttc ctcatttgca caacttgaac     1680

gagatattcc agtatgtttc aacaaccaca aaggttcctc caccagacat gacatcattt     1740

ccctatggca cccggcgatc tcccgccaag atatggccaa ccaccaaacg cccagcaatc     1800

actcctgcca acaatcccaa acactctaag gaccctcaca aaacagggcc tgaggacaca     1860

actgtcctca ttgaaaccaa acgagattat tccaccgaat taagt                     1905


<210>  5736
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5736
ctgtgctccg ggtcctcata ttttgtgctt gcaaatggac atatcctgcc caacagtgaa       60

aatgctcatg gccaatctct ggaagaagat tccgcattgg aagctttgct gaattttttc      120

tttccaacaa cttgcaatct gagggaaaat caggtggcaa agccttgtaa tgagctgcaa      180

gatcttagtg agagtgaatg tttgagacac aaatgctgtt tttcatcatc ggggaccacg      240

agcttcaaat gttttgctcc atttagagat gtgcctaaac ag                         282


<210>  5737
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  5737
gggatgttga aggaggagga cgatgacaca gaacgcttgc ccagcaaatg cgaagtgtgt       60

aagctgctga gcacagagct acaggcggaa ctgagtcgca ccggtcgatc tcgagaggtg      120

ctggagctgg ggcaggtgct ggatacaggc aagaggaaga gacacgtgcc ttacagcgtt      180

tcagagacaa ggctggaaga ggccttagag aatttatgtg agcggatcct ggactatagt      240

gttcacgctg agcgcaaggg ctcactgaga tatgccaagg gtcagagtca gaccatggca      300

acactgaaag gcctagtgca gaagggggtg aaggtggatc tggggatccc tctggagctt      360

tgggatgagc ccagcgtgga ggtcacatac ctcaagaagc agtgtgagac catgttggag      420

gagtttgaag acattgtggg agactggtac ttccaccatc aggagcagcc cctacaaaat      480

tttctctgtg aaggtcatgt gctcccagct gctgaaactg catgtctaca ggaaacttgg      540

actggaaagg agatcacaga tggggaagag aaaacagaag gggaggaaga gcaggaggag      600

gaggaggaag aggaggaaga ggaaggggga gacaagatga ccaagacagg aagccacccc      660

aaacttgacc gagaagatct t                                                681


<210>  5738
<211>  420
<212>  DNA
<213>  Homo Sapiens

<400>  5738
catgaaagcg cagccatggc ggcatctgca aacatagaga attctgggct tccacacaac       60

tccagtgcta actcaacaga gactctccaa catgtgcctt ctgaccatac aaatgaaact      120

tccaacagta ctgtgaaacc accaacttca gttgcctcag actccagtaa tacaacggtc      180

accaccatga aacctacagc ggcatctaat acaacaacac cagggatggt ctcaacaaat      240

atgacttcta ccaccttaaa gtctacaccc aaaacaacaa gtgtttcaca gaacacatct      300

cagatatcaa catccacaat gaccgtaacc cacaatagtt cagtgacatc tgctgcttca      360

tcagtaacaa tcacaacaac tatgcattct gaagcaaaga aaggatcaaa atttgatact      420


<210>  5739
<211>  1593
<212>  DNA
<213>  Homo Sapiens

<400>  5739
agcgaggcaa aggtcacccg gagttgtgca gagacccggc aggtgctggg ggcccgggga       60

tatagcttaa acctaatccc tcccgccctg atctcaggtg agcacctccg ggtctgtccc      120

caggagtaca cctgctgttc cagtgagaca gagcagaggc tgatcaggga gactgaggcc      180

accttccgag gcctggtgga ggacagcggc tcctttctgg ttcacacact ggctgccagg      240

cacagaaaat ttgatgagtt ttttctggag atgctctcag tagcccagca ctctctgacc      300

cagctcttct cccactccta cggccgcctg tatgcccagc acgccctcat attcaatggc      360

ctgttctctc ggctgcgaga cttctatggg gaatctggtg aggggttgga tgacaccctg      420

gcggatttct gggcacagct cctggagaga gtgttcccgc tgctgcaccc acagtacagc      480

ttcccccctg actacctgct ctgcctctca cgcttggcct catctaccga tggctctctg      540

cagccctttg gggactcacc ccgccgcctc cgcctgcaga taacccggac cctggtggct      600

gcccgagcct ttgtgcaggg cctggagact ggaagaaatg tggtcagcga agcgcttaag      660

gtgccggtgt ctgaaggctg cagccaggct ctgatgcgtc tcatcggctg tcccctgtgc      720

cggggggtcc cctcacttat gccctgccag ggcttctgcc tcaacgtggt tcgtggctgt      780

ctcagcagca ggggactgga gcctgactgg ggcaactatc tggatggtct cctgatcctg      840

gctgataagc tccagggccc cttttccttt gagctgacgg ccgagtccat tggggtgaag      900

atctcggagg gtttgatgta cctgcaggaa aacagtgcga aggtgtccgc ccaggtgttt      960

caggagtgcg gcccccccga cccggtgcct gcccgcaacc gtcgagcccc gccgccccgg     1020

gaagaggcgg gccggctgtg gtcgatggtg accgaggagg agcggcccac gacggccgca     1080

ggcaccaacc tgcaccggct ggtgtgggag ctccgcgagc gtctggcccg gatgcggggc     1140

ttctgggccc ggctgtccct gacggtgtgc ggagactctc gcatggcagc ggacgcctcg     1200

ctggaggcgg cgccctgctg gaccggagcc gggcggggcc ggtacttgcc gccagtggtc     1260

gggggctccc cggccgagca ggtcaacaac cccgagctca aggtggacgc ctcgggcccc     1320

gatgtcccga cacggcggcg tcggctacag ctccgggcgg ccacggccag aatgaaaacg     1380

gccgcactgg gacacgacct ggacgggcag gacgcggatg aggatgccag cggctctgga     1440

gggggacagc agtatgcaga tgactggatg gctggggctg tggctccccc agcccggcct     1500

cctcggcctc cataccctcc tagaagggat ggttctgggg gcaaaggagg aggtggcagt     1560

gcccgctaca accagggccg gagcaggagt ggg                                  1593


<210>  5740
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  5740
gttgataagg cagatgatga agatgatgag gatttaacgg tgaacaaaac ctgggtcttg       60

gccccaaaaa ttcatgaagg agatatcaca caaattctga attcattgct tcaaggctat      120

gacaataaac ttcgtccaga tataggagtg aggcccacag taattgaaac tgatgtttat      180

gtaaacagca ttggaccagt tgatccaatt aatatggaat atacaataga tataattttt      240

gcccaaacct ggtttgacag tcgtttaaaa ttcaatagta ccatgaaagt gcttatgctt      300

aacagtaata tggttggaaa aatttggatt cctgacactt tcttcagaaa ctcaagaaaa      360

tctgatgctc actggataac aactcctaat cgtctgcttc gaatttggaa tgatggacga      420

gttctgtata ctctaagatt gacaattaat gcagaatgtt atcttcagct tcataacttt      480

cccatggatg aacattcctg tccactggaa ttttcaagct atggataccc taaaaatgaa      540

attgagtata agtggaaaaa gccctccgta gaagtggctg atcctaaata ctggagatta      600

tatcagtttg catttgtagg gttacggaac tcaactgaaa tcactcacac gatctctggg      660

gattatgtta tcatgacaat tttttttgac ctgagcagaa gaatgggata t               711


<210>  5741
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  5741
agcaactggg gatgctatgg aaacatccaa agcctggaca cccctggagc atcttgtggg       60

attggaagac gtcacggcct gaactactgt ggagttcgtg cttctgaaag gctggctgaa      120

atagacatgc catacctcct gaaatatcaa cccatgatgc aaaccattgg ccaaaagtac      180

tgcatggatc ctgccgtgat cgctggtgtc ttgtccagga agtctcccgg tgacaaaatt      240

ctggtcaaca tgggcgatag gactagcatg gtgcaggacc ctggctctca agctcccaca      300

tcctggatta gtgagtctca ggtttcccag acaactgaag ttctgactac tagaatcaaa      360

gaaatccaga ggaggtttcc aacctggacc cctgaccagt acctgagagg tggactctgt      420

gcctacagtg ggggtgctgg ctatgtccga agcagccagg acctgagctg tgacttctgc      480

aatgatgtcc ttgcacgagc caagtacctc aagagacatg gcttc                      525


<210>  5742
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  5742
atacaggcca aactgatttt cttgaatttc gtaagagttc cctatttcat tgatttgaaa       60

aaaccacagg atcaaggttt gaatcacacg tgtaactact acctgcagcc agaggaagac      120

gtgaccattg gagtctggca caccgtccct gcagtctggt ggaagaacgc ccaaggcaaa      180

gaccagatgt ggtatgagga tgccttggct tccagccacc ctatcattct gtacctgcat      240

gggaacgcag gtaccagagg aggcgaccac cgcgtggagc tttacaaggt gctgagttcc      300

cttggttacc atgtggtcac ctttgactac agaggttggg gtgactcagt gggaacgcca      360

tctgagcggg gcatgaccta tgacgcactc cacgtttttg actggatcaa agcaagaagt      420

ggtgacaacc ccgtgtacat ctggggccac tctctgggca ctggcgtggc gacaaatctg      480

gtgcggcgcc tctgtgagcg agagacgcct ccagatgccc ttatattgga atctccattc      540

actaatatcc gtgaagaagc taagagccat ccattttcag tgatatatcg atacttccct      600

gggtttgact ggttcttcct tgatcctatt acaagtagtg gaattaaatt tgcaaatgat      660

gaaaacgtga agcacatctc ctgtcccctg ctcatcctgc acgctgagga cgacccggtg      720

gtgcccttcc agcttggcag aaagctctat agcatcgccg caccagctcg aagcttccga      780

gatttcaaag ttcagtttgt gccctttcat tcagaccttg gctacaggca caaatacatt      840

tacaagagcc ctgagctgcc acggatactg agacctcagc agggcccagg ttccagccca      900

gatcccagca tgtggtcaga gctggtg                                          927


<210>  5743
<211>  1896
<212>  DNA
<213>  Homo Sapiens

<400>  5743
caaaaattgg atgatgtgga cccactggtg gctaccaact ttggaaagat aagagggatt       60

aagaaggaac tcaataatga aattttgggg cctgttattc aatttcttgg ggttccatat      120

gcagccccac caacagggga acgtcgtttt cagcctccag aaccaccatc tccctggtca      180

gatatcagaa atgccactca atttgctcct gtgtgtcccc agaatatcat tgatggcaga      240

ttgccagaag tcatgcttcc tgtgtggttt actaataact tggatgtggt ttcatcatat      300

gtgcaagacc agagcgaaga ctgcctatat ttaaatatat atgtcccgac tgaggatgat      360

attcgggaca gtgggggtcc caaaccagtg atggtgtata tccatggtgg ctcatatatg      420

gaaggtactg gaaatttata tgatggaagt gtcttggcaa gttatggcaa tgtgatcgtc      480

atcacagtca actatcgact tggagtactc ggtttcttga gtacaggcga tcaggctgca      540

aaggggaact atggactcct tgatctcata caagctttaa gatggactag tgaaaacatt      600

ggattctttg gtggtgaccc cttaagaatc actgtttttg gatctggtgc tgggggttca      660

tgtgtcaacc tgctgacttt atcccattat tctgaaggta accgttggag caattcaacc      720

aaaggacttt ttcaacgagc aatagctcaa agtggaacag ccctttccag ctgggctgtt      780

agttttcaac ctgcaaaata tgctagaatg ttggccacaa aagttggttg caatgtttca      840

gatacagtag agttagtgga atgcctacag aagaagcctt acaaagaact tgttgaccaa      900

gatattcaac cagctcgata ccacatagcc tttggacctg tgattgatgg tgatgtaata      960

ccagacgacc cccagatatt gatggagcaa ggagagtttc tcaactatga tataatgtta     1020

ggagtgaacc aaggggaagg gttaaaattt gttgaaaata tagtagatag cgatgatggt     1080

atatcagcta gtgattttga ctttgctgtt tcaaattttg ttgataattt atatggatat     1140

cctgaaggca aagatgtttt gagagaaacc attaagttca tgtatactga ctgggctgac     1200

cgtcataacc ctgaaaccag aagaaagaca ttactggctt tgtttacgga ccatcagtgg     1260

gtggcaccag ctgtagccac agcggatctt cactcaaact ttggttcacc tacgtacttc     1320

tatgcctttt accatcattg ccaaacagat caggttccag cttgggctga tgcagcccac     1380

ggagacgagg ttccctatgt actgggaatc cccatgattg gccctacaga gttatttcct     1440

tgcaatttct ccaaaaatga tgtgatgctg agtgcagttg taatgacata ctggacaaat     1500

tttgctaaaa ctggtgaccc aaatcaacca gtccctcaag acacgaaatt cattcatacc     1560

aaacccaacc gttttgaaga agtagcatgg accagatatt cccagaaaga ccaactttat     1620

ctccatattg gattaaaacc aagagttaaa gaacattaca gagccaataa ggtgaacctc     1680

tggttggagt tggtacctca tctgcataat ctcaatgaca tttctcagta tacctctaca     1740

acaactaaag tgccatcaac tgacatcact ttcagaccta cgagaaaaaa ttctgtacct     1800

gtcacgtcag cctttcccac tgccaagcag gatgatccca aacaacaacc aagtccattt     1860

tcagtggatc aaagggacta ctcaacagag ctgagt                               1896


<210>  5744
<211>  2139
<212>  DNA
<213>  Homo Sapiens

<400>  5744
gcctcggagg cgccgtcccc gccgcggtcg ccgccgccgc ccacctcccc cgagcctgag       60

ctggcccagc taaggcggaa ggtggagaag ttggaacgtg aactgcggag ctgcaagcgg      120

caggtgcggg agatcgagaa gctgctgcat cacacagaac ggctgtacca gaacgcagaa      180

agcaacaacc aggagctccg cacgcaggtg gaagaactca gtaaaatact ccaacgtggg      240

agaaatgaag ataataaaaa gtctgatgta gaagtacaaa cagagaacca tgctccttgg      300

tcaatctcag attattttta tcagacgtac tacaatgacg ttagtcttcc aaataaagtg      360

actgaactgt cagatcaaca agatcaagct atcgaaactt ctattttgaa ttctaaagac      420

catttacaag tagaaaatga tgcttaccct ggtaccgata gaacagaaaa tgttaaatat      480

agacaagtgg accattttgc ctcaaattca caggagccag catctgcatt agcaacagaa      540

gatacctcct tagaaggctc atcattagct gaaagtttga gagctgcagc agaagcggct      600

gtatcacaga ctggatttag ttatgatgaa aatactggac tgtattttga ccacagcact      660

ggtttctatt atgattctga aaatcaactc tattatgatc cttccactgg aatttattac      720

tattgtgatg tggaaagtgg tcgttatcag tttcattctc gagtagattt gcaaccttat      780

ccgacttcta gcacaaaaca aagtaaagat aaaaaattga agaagaaaag aaaagatcca      840

gattcttctg caacaaatga ggaaaaggat ttgaactcag aggatcaaaa agccttcagt      900

gttgaacata caagctgcaa tgaggaagaa aatttcgcaa atatgaaaaa gaaggccaaa      960

ataggcattc atcacaaaaa tagtcccccc aaagtcactg ttccaactag tggaaatact     1020

atagagtctc ctcttcatga aaacatctct aattcaacat catttaaaga tgagaaaatc     1080

atggagactg atagtgaacc agaggaaggt gaaattacag actctcagac tgaggatagt     1140

tatgacgaag ccattaccag tgaaggcaat gtaactgcag aagatagtga ggatgaagat     1200

gaagacaaaa tttggccccc atgtattaga gtaattgtca ttagatcacc tgtgttgcag     1260

ataggatcac tctttatcat tactgctgta aaccctgcta caattggaag agaaaaggat     1320

atggaacata ctctccgaat ccctgaagtt ggtgtcagta agtttcatgc agaaatttat     1380

tttgaccatg acttacaaag ttatgtcctt gtggatcaag gcagtcaaaa tggcacaatt     1440

gttaatggaa aacagattct tcagccgaaa actaaatgtg acccttacgt acttgagcat     1500

ggagatgaag tcaaaattgg agaaactgtc ttatcctttc acattcatcc tggcagtgat     1560

acctgtgatg gctgtgaacg agggcaggtt agagcccacc ttcgccttga taagaaagat     1620

gaatcttttg ttggtccaac actaagtaag gaggaaaaag agttggaagg aagaaaagaa     1680

ttaaagaaaa tacgagtaaa atatggttta cagaatacag aatacgaaga tgaaaagaca     1740

ttgaagaatc caaaatataa agatagagct ggaaaacgta gggagcaggt tggaagtgaa     1800

ggaactttcc aaagagatga tgctcctgca tctgttcatt ctgaaattac tgatagcaac     1860

aaaggtcgga agttgttgga gaagatgggt tggaagaaag gagagggcct ggggaaggat     1920

ggtggaggaa tgaaaacgcc gatccagctt cagcttcggc gaacacatgc aggcttgggg     1980

acaggcaaac catcctcatt tgaagatgtt caccttctcc aaaacaagaa caaaaaaaac     2040

tgggacaaag cacgagagcg gtttactgaa aacttcccag aaactaagcc tcaaaaagat     2100

gacccaggga ccatgccttg ggtaaaaggg actttagag                            2139


<210>  5745
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  5745
aaagaaaatc aagacataaa cacaacacag aacattgcag aagtttttaa aacaatggaa       60

aataaaccta tttctttgga aagtgaagca aacttaaact cagataaaga aaatataacc      120

acctcaaatc tcaaggcgag tcattcccct cctttgaatc tacccaacaa cagccacgga      180

ataacagatt tctccagtaa ctcgtcagca gagcattctt tgggcagtct aaaacccaca      240

tctaccattt ccacaagccc tcccttgatc catagctttg tttctaaagt gccttggaat      300

gcacctatag cagatgaaga tcttttgccc atctcagcac atcccaatgc tacacctgct      360

ctgtcttcag aaaacttcac ttggtctttg gtcaatgaca ccgtgaaaac tcctgataac      420

agttccatta cagttagcat cctctcttca gaaccaactt ctccatctgt gacccccttg      480

atagtggaac caagtggatg gcttaccaca aacagtgata gcttcactgg gtttatccct      540

tatcaagaaa aaacaactct acagcctacc ttaaaattca ccaataattc aaaactcttt      600

ccaaatacgt cagatcccca aaaagaaaat agaaataca                             639


<210>  5746
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  5746
gcaaaccatc ataaagctca ccatgttaaa acgggaactt gtgaggtggt ggcactccac       60

agatactgta ataagaacaa gatagaagaa cggtcacaaa cagtcaagta ctcctgcttc      120

cctgggcagg tggcaggcac cacgcgagct gctccatcat gtgtggatgc ttcaatagtg      180

gaacagaaat ggtggtgcca tatgcagcca tgtctagagg gagaagaatg taaagttctt      240

ccggatcgga aaggatggag ctgttcctct gggaataaag tcaaaacaac tagggtaacc      300

cat                                                                    303


<210>  5747
<211>  1191
<212>  DNA
<213>  Homo Sapiens

<400>  5747
ctcattgatg gatctgaaat ggaatgggat tttatgtggc acttgagaaa ggtaccccgg       60

attgtcagtg aaaggacttt ccatctcacc agccccgcat ttgaggcaga tgctaagatg      120

atggtaaata cagtgtgtgg catcgaatgc cagaaagaac tcccaactcc cagcctttct      180

gaattggagg attatctttc ctatgagact gtctttgaga atggcacccg aaccttaacc      240

agggtgaaag ttcaagattt ggttcttgag ccgactcaaa atatcaccac aaagggagta      300

tctgttagga gaaagagaca ggtgtatggc accgacagca ggttcagcat cttggacaaa      360

aggttcttaa ccaatttccc tttcagcaca gctgtgaagc tttccacggg ctgtagtggc      420

attctcattt cccctcagca tgttctaact gctgcccact gtgttcatga tggaaaggac      480

tatgtcaaag ggagtaaaaa gctaagggta gggttgttga agatgaggaa taaaagtgga      540

ggcaagaaac gtcgaggttc taagaggagc aggagagaag ctagtggtgg tgaccaaaga      600

gagggtacca gagagcatct gcaggagaga gcgaagggtg ggagaagaag aaaaaaatct      660

ggccggggtc agaggattgc cgaagggagg ccttcctttc agtggacccg ggtcaagaat      720

acccacattc cgaagggctg ggcacgagga ggcatggggg acgctacctt ggactatgac      780

tatgctcttc tggagctgaa gcgtgctcac aaaaagaaat acatggaact tggaatcagc      840

ccaacgatca agaaaatgcc tggtggaatg atccacttct caggatttga taacgatagg      900

gctgatcagt tggtctatcg gttttgcagt gtgtccgacg aatccaatga tctcctttac      960

caatactgcg atgctgagtc gggctccacc ggttcggggg tctatctgcg tctgaaagat     1020

ccagacaaaa agaattggaa gcgcaaaatc attgcggtct actcagggca ccagtgggtg     1080

gatgtccacg gggttcagaa ggactacaac gttgctgttc gcatcactcc cctaaaatac     1140

gcccagattt gcctctggat tcacgggaac gatgccaatt gtgcttacgg c              1191


<210>  5748
<211>  2193
<212>  DNA
<213>  Homo Sapiens

<400>  5748
cagggcgcag ccctcgagga ccctgattat tacgggcagg agatctggag ccgggagccc       60

tactacgcgc gcccggagcc cgagctcgag accttctctc cgccgctgcc tgcggggccc      120

ggggaggagt gggagcggcg cccgcaggag cccaggccgc ccaagagggc caccaagccc      180

aagaaagctc ccaagaggga gaagtcggct ccggagccgc ctccaccagg taaacacagc      240

aacaaaaaag ttatgagaac caagagctct gagaaggctg ccaacgatga tcacagtgtc      300

cgtgtggccc gtgaagatgt cagagagagt tgcccacctc ttggtctgga aaccttaaaa      360

atcacagact tccagctcca tgcctccacg gtgaagcgct atggcctggg ggcacatcga      420

gggagactca acatccaggc gggcattaat gaaaatgatt tttatgacgg agcgtggtgc      480

gcgggaagaa atgacctcca gcagtggatt gaagtggatg ctcggcgcct gaccagattc      540

actggtgtca tcactcaagg gaggaactcc ctctggctga gtgactgggt gacatcctat      600

aaggtcatgg tgagcaatga cagccacacg tgggtcactg ttaagaatgg atctggagac      660

atgatatttg agggaaacag tgagaaggag atccctgttc tcaatgagct acccgtcccc      720

atggtggccc gctacatccg cataaaccct cagtcctggt ttgataatgg gagcatctgc      780

atgagaatgg agatcctggg ctgcccactg ccagatccta ataattatta tcaccgccgg      840

aacgagatga ccaccactga tgacctggat tttaagcacc acaattataa ggaaatgcgc      900

cagttgatga aagttgtgaa tgaaatgtgt cccaatatca ccagaattta caacattgga      960

aaaagccacc agggcctgaa gctgtatgct gtggagatct cagatcaccc tggggagcat     1020

gaagtcggtg agcccgagtt ccactacatc gcgggggccc acggcaatga ggtgctgggc     1080

cgggagctgc tgctgctgct ggtgcagttc gtgtgtcagg agtacttggc ccggaatgcg     1140

cgcatcgtcc acctggtgga ggagacgcgg attcacgtcc tcccctccct caaccccgat     1200

ggctacgaga aggcctacga agggggctcg gagctgggag gctggtccct gggacgctgg     1260

acccacgatg gaattgacat caacaacaac tttcctgatt taaacacgct gctctgggag     1320

gcagaggatc gacagaatgt ccccaggaaa gttcccaatc actatattgc aatccctgag     1380

tggtttctgt cggaaaatgc cacggtggct gccgagacca gagcagtcat agcctggatg     1440

gaaaaaatcc cttttgtgct gggcggcaac ctgcagggcg gcgagctggt ggtggcgtat     1500

ccctacgacc tggtgcggtc cccctggaag acgcaggaac acacccccac ccccgatgac     1560

cacgtgttcc gctggctggc ctactcctat gcctccacac accgcctcat gacagacgcc     1620

cggaggaggg tgtgccacac ggaggacttc cagaaggagg agggcactgt caatggggcc     1680

tcctggcaca ccgtcgctgg aagtctgaac gatttcagct accttcatac aaactgcttc     1740

gaactgtcca tctacgtggg ctgtgataaa tacccacatg agagccagct gcccgaggag     1800

tgggagaata accgggaatc tctgatcgtg ttcatggagc aggttcatcg tggcattaaa     1860

ggcttggtga gagattcaca tggaaaagga atcccaaacg ccattatctc cgtagaaggc     1920

attaaccatg acatccgaac agccaacgat ggggattact ggcgcctcct gaaccctgga     1980

gagtatgtgg tcacagcaaa ggccgaaggt ttcactgcat ccaccaagaa ctgtatggtt     2040

ggctatgaca tgggggccac aaggtgtgac ttcacactta gcaaaaccaa catggccagg     2100

atccgagaga tcatggagaa gtttgggaag cagcccgtca gcctgccagc caggcggctg     2160

aagctgcggg ggcggaagag acgacagcgt ggg                                  2193


<210>  5749
<211>  849
<212>  DNA
<213>  Homo Sapiens

<400>  5749
agcgagtacg actacgtgag cttccagtcg gacatcggcc cgtaccagag cgggcgcttc       60

tacaccaagc cacctcagtg cgtggacatc cccgcggacc tgcggctgtg ccacaacgtg      120

ggctacaaga agatggtgct gcccaacctg ctggagcacg agaccatggc ggaggtgaag      180

cagcaggcca gcagctgggt gcccctgctc aacaagaact gccacgccgg cacccaggtc      240

ttcctctgct cgctcttcgc gcccgtctgc ctggaccggc ccatctaccc gtgtcgctgg      300

ctctgcgagg ccgtgcgcga ctcgtgcgag ccggtcatgc agttcttcgg cttctactgg      360

cccgagatgc ttaagtgtga caagttcccc gagggggacg tctgcatcgc catgacgccg      420

cccaatgcca ccgaagcctc caagccccaa ggcacaacgg tgtgtcctcc ctgtgacaac      480

gagttgaaat ctgaggccat cattgaacat ctctgtgcca gcgagtttgc actgaggatg      540

aaaataaaag aagtgaaaaa agaaaatggc gacaagaaga ttgtccccaa gaagaagaag      600

cccctgaagt tggggcccat caagaagaag gacctgaaga agcttgtgct gtacctgaag      660

aatggggctg actgtccctg ccaccagctg gacaacctca gccaccactt cctcatcatg      720

ggccgcaagg tgaagagcca gtacttgctg acggccatcc acaagtggga caagaaaaac      780

aaggagttca aaaacttcat gaagaaaatg aaaaaccatg agtgccccac ctttcagtcc      840

gtgtttaag                                                              849


<210>  5750
<211>  1314
<212>  DNA
<213>  Homo Sapiens

<400>  5750
tccacgccag gcaccgtggt ccgactcaac aaggcagcat tgagctacgt gtctgaaatt       60

gggaaagccc ctctccagcg ggccctgcag gtcactgtcc ctcatttcct ggactggagt      120

ggagaggcgc ttcagcccac caggatccgg attctgaatg tccatgtgcc ccgcctccac      180

ctgaaattca ttgctggttt cggagtgcgc ctgctggcag cagctaattt tactttcaag      240

gtctttcgcg ccccagagcc cctggagctg acgctgcctg tggaactgct ggctgacacc      300

cgcgtgaccc agagctccat caggacccct gtggtcagca tctctgcctg ctctttattc      360

tcgggccacg ccaacgagtt tgatggcagt aacagcacct cccacgcgct gctggtcctg      420

gtgcagaagc acattaaagc tgtcttgagt aacaagctgt gcctgagcat ctccaacctg      480

gtgcagggtg tcaatgtcca cctgggcacc ttaattggcc tcaaccccgt gggtcctgag      540

tcccagatcc gctattccat ggtcagtgtg cccactgtca ccagtgacta catttccctg      600

gaagtcaatg ctgttctctt cctgctgggc aagcccatca tcctgcccac ggatgccacc      660

ccttttgtgt tgccaaggca tgtgggtacc gagggctcca tggccaccgg gggcctctcc      720

cagcagctgt ttgactctgc gctcctgctg ctgcagaagg ccggtgccct caacctggac      780

atcacagggc agctgaggtc ggatgacaac ctgctgaaca cctctgctct gggccggctc      840

atcccggagg tggcccgcca gtttcccgag cccatgcctg tggtgctcaa ggtgcggctg      900

ggtgccacac ctgtggccat gctccacaca aacaacgcca ccctgcggct gcagcccttc      960

gtggaggtcc tggccacagc ctccaactcg gctttccagt ccctcttctc cctggatgtg     1020

gtagtgaact tgagactcca gctctctgtg tccaaggtga agcttcaggg gaccacgtct     1080

gtgctggggg atgtccagct cacggtggcc tcctccaacg tgggcttcat tgatacagat     1140

caggtgcgca cactgatggg caccgttttt gagaagcccc tgctggacca tctcaatgct     1200

ctcttggcca tgggaattgc cctccctggt gtggtcaacc tccactatgt cgcccctgag     1260

atctttgtct atgagggcta cgtggtgata tccagtggac tcttctacca gagc           1314


<210>  5751
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  5751
tccctctctg gatataatta tgaagtttat cactccttag aagaaattca aaattggatg       60

catcatctga ataaaactca ctcaggcctc attcacatgt tctctattgg aagatcatat      120

gagggaagat gtctttttat tttaaagctg ggcagacgat cacgactcaa aagagctgtt      180

tggatagact gtggtattca tgcaagagaa tggattggtc ctgccttttg tcagtggttt      240

gtaaaagaag ctcttctaac atataagagt gacccagcca tgagaaaaat gttgaatcat      300

ctatatttct atatcatgcc tgtgtttaac gtcgatggat accattttag ttggaccaat      360

gatcgatttt ggagaaaaac aaggtcaagg aactcaaggt ttcgctgccg tggagtggat      420

gccaatagaa actggaaagt gaagtggtgt gatgaaggag cttctatgca cccttgtgat      480

gacacatact gtggcccttt tccagaatct gagccggaag tgaaggctgt agctaacttc      540

cttcgaaaac acagaaagca cattagggct tatctctcct ttcatgcata tgctcagatg      600

ttactgtatc cctattctta caaatatgca acaattccca attttagatg tgtggaatct      660

gcagcttata aagctgtgaa tgcacttcag tcagtatacg gggtacgata cagatatgga      720

ccagcctcca caacgttgta tgtgagctct ggtagctcaa tggattgggc ctacaaaaat      780

ggaatacctt atgcatttgc tttcgaacta cgtgacactg gatattttgg atttttactc      840

ccagagatgc tcatcaaacc cacctgtaca gaaactatgc tggctgtgaa aaatatcaca      900

atgcacctgc taaagaaatg tccc                                             924


<210>  5752
<211>  1221
<212>  DNA
<213>  Homo Sapiens

<400>  5752
aaccacgccc acgcgccggg cacggcgccc ccacctgtcg tcagcactgg ggctgccagc       60

gccaacagcg ccgtggtcac tgtggaaagg gcggacagct cgcacctcag catcctcatt      120

gacccgcgct gccccgacct caccgacagc ttcgcacgcc tggagagcgc ccaggcctcg      180

gtgctgcagg cgctgacaga gcaccaggcc cagccacggc tggtgggcga ccaggagcag      240

gagctgctgg acacgctggc cgaccagctg ccccggctgc tggcccgagc ctcagagctg      300

cagacggagt gcatggggct gcggaagggg catggcacgc tgggccaggg cctcagcgcc      360

ctgcagagtg agcagggccg cctcatccag cttctctctg agagccaggg ccacatggct      420

cacctggtga actccgtcag cgacatcctg gatgccctgc agagggaccg ggggctgggc      480

cggccccgca acaaggccga ccttcagaga gcgcctgccc ggggaacccg gccccggggc      540

tgtgccactg gctcccggcc ccgagactgt ctggacgtcc tcctaagcgg acagcaggac      600

gatggcgtct actctgtctt tcccacccac tacccggccg gcttccaggt gtactgtgac      660

atgcgcacgg acggcggcgg ctggacggtg tttcagcgcc gggaggacgg ctccgtgaac      720

ttcttccggg gctgggatgc gtaccgagac ggctttggca ggctcaccgg ggagcactgg      780

ctagggctca agaggatcca cgccctgacc acacaggctg cctacgagct gcacgtggac      840

ctggaggact ttgagaatgg cacggcctat gcccgctacg ggagcttcgg cgtgggcttg      900

ttctccgtgg accctgagga agacgggtac ccgctcaccg tggctgacta ttccggcact      960

gcaggcgact ccctcctgaa gcacagcggc atgaggttca ccaccaagga ccgtgacagc     1020

gaccattcag agaacaactg tgccgccttc taccgcggtg cctggtggta ccgcaactgc     1080

cacacgtcca acctcaatgg gcagtacctg cgcggtgcgc acgcctccta tgccgacggc     1140

gtggagtggt cctcctggac cggctggcag tactcactca agttctctga gatgaagatc     1200

cggccggtcc gggaggaccg c                                               1221


<210>  5753
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  5753
tcgccattgt ctgcggcgcg ggcggccctg cgggtctacg cggtaggcgc cgcggtgatc       60

ctggcgcagc tgctgcggcg ctgccgcggg ggcttcctgg agccagtttt ccccccacga      120

cctgaccgtg tcgctatagt gacgggaggg acagatggca ttggctattc tacagcgaag      180

catctggcga gacttggcat gcatgttatc atagctggaa ataatgacag caaagccaaa      240

caagttgtaa gcaaaataaa agaagaaacc ttgaacgaca aagtggaatt tttatactgt      300

gacttggctt ccatgacttc catccggcag tttgtgcaga agttcaagat gaagaagatt      360

cctctccatg tcctgatcaa caatgctggg gtgatgatgg tccctcagag gaaaaccaga      420

gatggattcg aagaacattt cggcctgaac tacctagggc acttcctgct gaccaacctt      480

ctcttggata cgctgaaaga gtctgggtcc cctggccaca gtgcgagggt ggtcaccgtc      540

tcctctgcca cccattacgt cgctgagctg aacatggatg accttcagag cagtgcctgc      600

tactcacccc acgcagccta cgcccagagc aagctggccc ttgtcctgtt cacctaccac      660

ctccagcggc tgctggcggc tgagggaagc cacgtgaccg ccaacgtggt ggaccccggg      720

gtggtcaaca cggacctcta caagcacgtg ttctgggcca cccgtctggc gaagaagctt      780

ctcggctggt tgcttttcaa gacccccgat gaaggagcgt ggacttccat ctacgcagca      840

gtcaccccag agctggaagg agttggtggc cgttacctat acaacgagaa agagaccaag      900

tccctccacg tcacctacaa ccagaaactg cagcagcagc tgtggtctaa gagttgtgag      960

atgactgggg tccttgatgt gaccctg                                          987


<210>  5754
<211>  219
<212>  DNA
<213>  Homo Sapiens

<400>  5754
ctttacttca aaatacacaa cgcgctaaaa gctgcaaagg aacctgaagc tgtggctgta       60

aaaaatcaca acccagacaa ggtgtggtgg gccaagaaca gccaggccaa aaccattgcc      120

acggagtctt gtcctgccct gcagtgctgt gaaggatata gaatgtgtgc cagttttgat      180

tccctgccac cttgctgttg cgacataaat gagggcctc                             219


<210>  5755
<211>  2223
<212>  DNA
<213>  Homo Sapiens

<400>  5755
ttaaccccag atgaactcac aaattcgtca gaaaccagat tgtctttgga agacctcttt       60

aggaaagact ttgtgcttca cgatccagag gctcggtgga tcaatgatac agatgtggtg      120

tataaaagcg agaatggaca tgtcattaaa ctgaatatag aaacaaatgc taccacatta      180

ttattggaaa acacaacttt tgtaaccttc aaagcatcaa gacattcagt ttcaccagat      240

ttaaaatatg tccttctggc atatgatgtc aaacagattt ttcattattc atatactgct      300

tcatatgtga tttacaacat acacactagg gaagtttggg agttaaatcc tccagaagta      360

gaggactccg tcttgcagta cgcggcctgg ggtgtccaag ggcagcagct gatttatatt      420

tttgaaaata atatctacta tcaacctgat ataaagagca gttcattgcg actgacatct      480

tctggaaaag aagaaataat ttttaatggg attgctgact ggttatatga agaggaactc      540

ctgcattctc acatcgccca ctggtggtca ccagatggag aaagacttgc cttcctgatg      600

ataaatgact ctttggtacc caccatggtt atccctcggt ttactggagc gttgtatccc      660

aaaggaaagc agtatccgta tcctaaggca ggtcaaatga acccaacaat aaaattatat      720

gttgtaaacc tgtatggacc aactcacact ttggagctca tgccacctga cagctttaaa      780

tcaagagaat actatatcac tatggttaaa tgggtaagca ataccaagac tgtggtaaga      840

tggttaaacc gagctcagaa catctccatc ctcacagtct gtgagaccac tacaggtgct      900

tgtagtaaaa aatatgagat gacatcagat acgtggctct ctcagcagaa tgaggagccc      960

gtgttttcta gagacggcag caaattcttt atgacagtgc ctgttaagca agggggacgt     1020

ggagaatttc accacatagc tatgttcctc atccagagta aaagtgagca aattaccgtg     1080

cggcatctga catcaggaaa ctgggaagtg ataaagatct tggcatacga tgaaactact     1140

caaaaaattt actttctgag cactgaatct tctcccagag gaaggcagct gtacagtgct     1200

tctactgaag gattattgaa tcgccaatgc atttcatgta atttcatgaa agaacaatgt     1260

acatattttg atgccagttt tagtcccatg aatcaacatt tcttattatt ctgtgaaggt     1320

ccaagggtcc cagtggtcag cctacatagt acggacaacc cagcaaaata ttttatattg     1380

gaaagcaatt ctatgctgaa ggaagctatc ctgaagaaga agataggaaa gccagaaatt     1440

aaaatccttc atattgacga ctatgaactt cctttacagt tgtcccttcc caaagatttt     1500

atggaccgaa accagtatgc tcttctgtta ataatggatg aagaaccagg aggccagctg     1560

gttacagata agttccatat tgactgggat tccgtactca ttgacatgga taatgtcatt     1620

gtagcaagat ttgatggcag aggaagtgga ttccagggtc tgaaaatttt gcaggagatt     1680

catcgaagat taggttcagt agaagtaaag gaccaaataa cagctgtgaa atttttgctg     1740

aaactgcctt acattgactc caaaagatta agcatttttg gaaagggtta tggtggctat     1800

attgcatcaa tgatcttaaa atcagatgaa aagcttttta aatgtggatc cgtggttgca     1860

cctatcacag acttgaaatt gtatgcctca gctttctctg aaagatacct tgggatgcca     1920

tctaaggaag aaagcactta ccaggcagcc agtgtgctac ataatgttca tggcttgaaa     1980

gaagaaaata tattaataat tcatggaact gctgacacaa aagttcattt ccaacactca     2040

gcagaattaa tcaagcacct aataaaagct ggagtgaatt atactatgca ggtctaccca     2100

gatgaaggtc ataacgtatc tgagaagagc aagtatcatc tctacagcac aatcctcaaa     2160

ttcttcagtg attgtttgaa ggaagaaata tctgtgctac cacaggaacc agaagaagat     2220

gaa                                                                   2223


<210>  5756
<211>  174
<212>  DNA
<213>  Homo Sapiens

<400>  5756
caaatatatc ctccacttcc tgagagaaca ttgccattgc accttgatat ccaaggctgt       60

aacagcacct acaatgagac aaatttgatg acaaccacag aaatgccatt tactactagt      120

gtttttcaaa tatacaatgt tcaaaggact ccactgatgg ataactggta ttct            174


<210>  5757
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5757
cagtggaagc agtcttccta cgcaggcgac gccatcatca ctgccgtggg cctctatgaa       60

gggctctgga tgtcctgcgc ctcccagagc actgggcaag tgcagtgcaa gctctacgac      120

tcgctgctcg ccctggacgg tcacatccaa tcagcgcgg                             159


<210>  5758
<211>  2811
<212>  DNA
<213>  Homo Sapiens

<400>  5758
gtctacgaag accaagtggg caagtttgat tggagacagc aatatgttgg gaaggtcaag       60

tttgcctcct tggaattttc ccctggatcc aagaagttgg ttgtagccac agagaagaat      120

gtgattgcag cattaaattc ccgaactggg gagatcttgt ggcgccatgt tgacaagggc      180

acggcagaag gggctgtgga tgccatgctg ctgcacggac aggatgtgat cactgtgtcc      240

aatggaggcc gaatcatgcg ttcctgggag actaacatcg ggggcctgaa ctgggagata      300

accctggaca gtggcagttt ccaggcactt gggctggttg gcctgcagga gtctgtaagg      360

tacatcgcag tcctgaagaa gactacactt gccctccatc acctctccag tgggcacctc      420

aagtgggtgg aacatctccc agaaagtgac agcatccact accagatggt gtattcttac      480

ggctctgggg tggtgtgggc cctcggagtt gttcccttca gccatgtgaa cattgtcaag      540

tttaatgtgg aagatggaga gattgttcag caggttaggg tttcaactcc gtggctgcag      600

cacctgtctg gagcctgtgg tgtggtggat gaggctgtcc tggtgtgtcc tgacccgagc      660

tcacgttccc tccaaacttt ggctctggag acggaatggg agttgagaca gatcccactg      720

cagtctctcg acttagaatt tggaagtgga ttccaacccc gggtcctgcc tacccagccc      780

aacccagtgg acgcttcccg ggcccagttc ttcctgcact tgtccccaag ccactatgct      840

ctgctgcagt accattatgg aacgctgagt ttgcttaaaa acttcccaca gactgcccta      900

gtgagctttg ccaccactgg ggagaagacg gtggctgcag tcatggcctg tcggaatgaa      960

gtgcagaaaa gtagcagttc tgaagatggg tcaatgggga gcttttcgga gaagtctagt     1020

tcaaaggact ctctggcttg cttcaatcag acctacacca ttaacctata cctcgtggag     1080

acaggtcggc ggctgctgga caccacgata acatttagcc tggaacagag cggcactcgg     1140

cctgagcggc tgtatatcca ggtgttcttg aagaaggatg actcagtggg ctaccgggct     1200

ttggtgcaga cagaggatca tctgctactt ttcctgcagc agttggcagg gaaggtggtg     1260

ctgtggagcc gtgaggagtc cctggcagaa gtggtgtgcc tagagatggt ggacctcccc     1320

ctgactgggg cacaggccga gctggaagga gaatttggca aaaaggcaga tggcttgctg     1380

gggatgttcc tgaaacgcct ctcgtctcag cttatcctgc tgcaagcatg gacttcccac     1440

ctctggaaaa tgttttatga tgctcggaag ccccggagtc agattaagaa tgagatcaac     1500

attgacaccc tggccagaga tgaattcaac ctccagaaga tgatggtgat ggtaacagcc     1560

tcaggcaagc tttttggcat tgagagcagc tctggcacca tcctgtggaa acagtatcta     1620

cccaatgtca agccagactc ctcctttaaa ctgatggtcc agagaactac tgctcatttc     1680

ccccatcccc cacagtgcac cctgctggtg aaggacaagg agtcgggaat gagttctctg     1740

tatgtcttca atcccatttt tgggaagtgg agtcaggtag ctcccccagt gctgaagcgc     1800

cccatcttgc agtccttgct tctcccagtc atggatcaag actacgccaa ggtgttgctg     1860

ttgatagatg atgaatacaa ggtcacagct tttccagcca ctcggaatgt cttgcgacag     1920

ctacatgagc ttgccccttc catcttcttc tatttggtgg atgcagagca gggacggctg     1980

tgtggatatc ggcttcgaaa ggatctcacc actgagctga gttgggagct gaccattccc     2040

ccagaagtac agcggatcgt caaggtgaag gggaaacgca gcagtgagca cgttcattcc     2100

cagggccgtg tgatggggga ccgcagtgtg ctctacaaga gcctgaaccc caacctgctg     2160

gccgtggtga cagagagcac agacgcgcac catgagcgca cctttattgg catcttcctc     2220

attgatggcg tcactgggcg tatcattcac tcctctgtgc agaagaaagc caaaggccct     2280

gtccatatcg tgcattcaga gaactgggtg gtgtaccagt actggaacac caaggctcgg     2340

cgcaacgagt ttaccgtact ggagctctat gagggcactg agcaatacaa cgccaccgcc     2400

ttcagctccc tggaccgccc ccagctgccc caggtcctcc agcagtccta tatcttcccg     2460

tcctccatca gtgccatgga ggccaccatc accgaacggg gcatcaccag ccgacacctg     2520

ctgattggac taccttctgg agcaattctt tcccttccta aggctttgct ggatccccgc     2580

cgccccgaga tcccaacaga acaaagcaga gaggagaact taatcccgta ttctccagat     2640

gtacagatac acgcagagcg attcatcaac tataaccaga cagtttctcg aatgcgaggt     2700

atctacacag ctccctcggg tctggagtcc acttgtttgg ttgtggccta tggtttggac     2760

atttaccaaa ctcgagtcta cccatccaag cagtttgacg ttctgaagga t              2811


<210>  5759
<211>  1692
<212>  DNA
<213>  Homo Sapiens

<400>  5759
tcaccagagg ttaacgccgg tgtttccagc atccacataa ccaagcctgt gcacatcctg       60

gaggaacgca gtctcctagt gctaacgccc gctggcctga cccagatgct gaaccagacc      120

cgcttcctca tggtgctttt ccacaaccca tcctcaaagc aatccaggaa cttggcggaa      180

gagctgggca aagctgtgga gatcatgggc aaaggcaaga atgggatcgg ctttggcaaa      240

gtggacatta ccatagagaa ggagcttcag caggagtttg ggattaccaa ggccccggag      300

ttgaagctgt tttttgaggg caacaggtca gagcccatca gctgcaaagg agtggttgaa      360

tctgctgcct tagtcgtttg gttgagacga caaattagcc agaaagcatt tttgttcaac      420

agcagcgagc aggtggcaga gtttgtgata tccaggccct tggtcatcgt tggcttcttc      480

caggatttag aggaagaagt agcagagttg ttctatgatg tgatcaaaga ctttccagag      540

ctaacgtttg gagtcataac gattggcaat gtcattgggc gtttccacgt cacccttgac      600

agcgtcctgg tgttcaaaaa gggaaaaatt gtgaaccgcc aaaagcttat taatgacagt      660

accaacaaac aggaactcaa tcgtgtcata aaacagcacc ttacagattt tgtgatcgaa      720

tacaacactg agaataagga tctgatttcc gagttgcaca tcatgagtca catgctgctg      780

tttgtctcca aaagctccga gtcatatggt atcataattc agcattataa gctggcatca      840

aaggaattcc aaaacaagat ccttttcatc cttgtggatg cagacgaacc cagaaatgga      900

cgtgtcttca agtacttccg ggtcacagag gtcgatatcc catccgtcca aatcctaaac      960

ttgagctctg acgccaggta caaaatgcct tcagatgaca taacctacga aagcctcaag     1020

aaatttggcc gcagcttcct gagtaaaaat gccacaaaac atcaatccag tgaagagatt     1080

ccaaaatact gggaccaggg actggttaag cagctcgtgg ggaagaactt caacgtagtc     1140

gtctttgaca aagaaaagga cgtatttgtg atgttctatg caccctggtc taaaaagtgc     1200

aagatgctgt tcccactgtt ggaggaattg ggcagaaaat atcaaaacca ctccacaatt     1260

atcattgcca agatcgatgt cacagcaaat gacattcagc tgatgtacct ggaccggtac     1320

ccattcttca ggctgttccc cagcggctct caacaagctg tcctgtataa gggagaacac     1380

accctgaagg gcttctctga cttcctggaa agccacatca aaactaagat tgaggatgag     1440

gatgagctgt tgtctgttga gcaaaatgaa gtgatagaag aggaagtgct agctgaggaa     1500

aaggaggtgc ctatgatgag gaaagggtta cctgaacagc agtcgcctga gctggagaac     1560

atgaccaagt acgtatccaa gctggaagag cccgctggga agaagaaaac atctgaggag     1620

gtggtggtgg tggtggctaa gccaaaggga cctccagtgc aaaagaagaa accaaaagtc     1680

aaggaagaac tt                                                         1692


<210>  5760
<211>  780
<212>  DNA
<213>  Homo Sapiens

<400>  5760
atggcttccg cagtctgggg gagtgccccc tggtggggcc cgccgccccc ggccccagct       60

cggccgctca cggacatcga cttctgctcc ggggcgcagc tgcaggaatt gacccagctg      120

atccaggagc tgggtgtgca ggagagctgg agtgacgggc ccaagccggg agccgatctc      180

ctccgggcca aggactttgt cttctctttg cttggtctag ttcaccgccg ggaccctcgc      240

tttcctcccc aggcagagct cttgctgctt cgtggtggga ttcgcgaggg ctccctggat      300

ctggggcatg cacccctggg tccctacgcc cggggacctc actacgatgc cggcttcaca      360

ctcctagtgc ccatgttttc actggacggc actgaactgc aactggacct ggaatcctgt      420

tacgcacagg tctgcctccc agagatggtg tgcggaaccc ccatccggga gatgtggcag      480

gattgcttag gacccccagt cccaggagca cgtgattcga tccaccgaac ggagagcgaa      540

gaaagttcca aggactggca aagctctgta gaccagccgc acagctacgt cactgagcac      600

gaggcgccgg tgtctttgga aaaatcgcct agtgacgttt cagcgtccga gtcgcctcag      660

catgacgtcg tcgaccttgg ctctaccgca cctttgaaaa caatgagtag tgacgtcacc      720

aaggcagccg tcgaaagccc agtcccaaag ccgtcggagg ctcgggaagc gtggcccaca      780


<210>  5761
<211>  225
<212>  DNA
<213>  Homo Sapiens

<400>  5761
accatgttca tcagcaccga gcagactgag cgggattctg ccaccgccta tcggatgact       60

gtggaagtgc tgggcacagt gctgggcacg gcgatccagg gacaaatcgt gggccaagca      120

gacacgcctt gtttccagga cctcaatagc tctacagtag cttcacaaag tgccaaccat      180

acacatggca ccacctcaca cagggaaacg caaaaggcat acctg                      225


<210>  5762
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  5762
atagagttca cgggccttcg ttctaacctg tctgggcccc agcagatcag tctttttgat       60

ttgccatcgg agtggtatct aaagacccgt cagagtgttc agcaatttac agtctgtcag      120

attggattgt ctgtgttttc cgctattgaa ggagaggcaa acaagtatat agcccattcg      180

tgtaacttct atctcttccc tacaacgttt gggattttgg actcagaatt ctccttccag      240

gcttccagtg ttcagttttt gaatcagtat ggcttcaact ataacaagtt tctcaaaaac      300

ggaatcccat atatgaatga agaacaggag aagaaaatta gacacgatat cctgactggg      360

aactggagag ttcgcagctc tccggataaa gaccaaatca aggtggtgat tgacgaagtg      420

acgcggtggc tggagctggc caaggaaggc gactggatga ctcttcctgg gatcactggc      480

ttccaggcct ttgaggtcca actggtgctg aggcaggccc tccccaacat ctggacggtg      540

ctgaaagatg agggggtggt agtgaagaaa gtgagtaaac aacatcgttg gtatcttcag      600

aacacctctt gtgaccgaga gagctgttgg aaggaaaata ttcttctctc agcaaggggt      660

ttttctgtct ttttccaaat gctggtgaaa gcccagaagc ccttagtggg acataatatg      720

atgatggacc tgctgcacct ccatgagaag ttcttcagac ccctcccaga aagctacgat      780

caatttaagc agaatatcca cagcctattt cctgttctca ttgataccaa gagtgtaaca      840

aaggatatct ggaaggagat gaatttcccg agggtgtcga atctttcgga agtctatgaa      900

gtcctgaaca gtgacttgaa tcccaccaag aattctggac cagagattgt tcacgcgagc      960

aggtgtgaga aatatgttga gacaaagtgc ccccacgaag ccgcgtatga tgccttcctc     1020

tgtgggtcag ttcttttgaa agtggcacac ttgcttctac agaagatata ccacatcgac     1080

cccgtgcccg agtcatcctt tcctcagtac cttgacgtgc tggctcctta cgtgaaccaa     1140

gtgaacctca tccgagcggg ggtcccaaag atcaattttt ctggtccaga ttatcccagt     1200

atccgacctc ccatcctcat cctcagcgtc aaaaggtggc ctggggtcag cgagcagcaa     1260

gtctaccata agtttcagaa tctctgcaag tttgatgtca ggcgactcac aagaagccag     1320

ttcttactcc tgaccaataa gtttaaggat gcgcggaaca tcctgaagga gtaccgggac     1380

cacccgaccc tgtgcatctc cctgtaccgc tactggaggc actccccaaa c              1431


<210>  5763
<211>  546
<212>  DNA
<213>  Homo Sapiens

<400>  5763
ttcaacctgc aggtggccac ccctgggggg aaagccatgg aatttgtgga tgtgactgag       60

agcaatgcac gctgggtgca agacttccgc ctcaaggctt acgccagccc cgccaagctc      120

gagtccatcg atggtgcccg gtaccatgcc ctcctgatcc ccagctgtcc tggggccctg      180

accgacctgg ccagcagtgg ctccctggcc cgtatcctgc agcacttcca ctctgagagc      240

aaacccatct gcgccgtcgg ccacggtgtc gccgccctgt gctgtgccac caacgaggac      300

agatcctggg tgttcgacag ctacagcctg acagggccct ctgtgtgtga gctcgtcagg      360

gcccccggct tcgcccgcct gccgctcgtg gtggaggact tcgtgaagga ttcgggcgcc      420

tgcttcagtg caagcgagcc tgacgctgtc cacgtcgtgc tggaccgcca cctggtcaca      480

ggccagaatg ccagctccac tgtcccggcc gtgcagaacc tgctcttcct ctgtggcagc      540

cggaag                                                                 546


<210>  5764
<211>  834
<212>  DNA
<213>  Homo Sapiens

<400>  5764
catctggggg ttctggggcc caagaacgtc tcgcagaaag acgccgagtt tgagcgcacc       60

tacgtggacg aggtcaacag cgagctggtc aacatctaca ccttcaacca tactgtgacc      120

cgcaacagga cagagggcgt gcgtgtgtct gtgaacgtcc tgaacaagca gaagggggcg      180

ccgttgctgt ttgtggtccg ccagaaggag gctgtggtgt ccttccaggt gcccctaatc      240

ctgcgaggga tgtttcagcg caagtacctc taccaaaaag tggaacgaac cctgtgtcag      300

ccccccacca agaatgagtc ggagattcag ttcttctacg tggatgtgtc caccctgtca      360

ccagtcaaca ccacatacca gctccgggtc agccgcatgg acgattttgt gctcaggact      420

ggggagcagt tcagcttcaa taccacagca gcacagcccc agtacttcaa gtatgagctc      480

cctgaaggcg tggactcggt aattgtcaag gtgacctcca acaaggcctt cccctgctca      540

gtcatctcca ttcaggatgt gctgtgtcct gtctatgacc tggacaacaa cgtagccttc      600

atcggcatgt accagacgat gaccaagaag gcggccatca ccgtacagcg caaagacttc      660

cccagcaaca gcttttatgt ggtggtggtg gtgaagaccg aagaccaagc ctgcgggggc      720

tccctgcctt tctacccctt cgcagaagat gaaccggtcg atcaagggca ccgccagaaa      780

accctgtcag tgctggtgtc tcaagcagtc acgtctgagg catacgtcag tggg            834


<210>  5765
<211>  1023
<212>  DNA
<213>  Homo Sapiens

<400>  5765
agccaggagg ccgggaccgg tgcgggcgcg gggtcccttg cgggttcttg cggctgcggc       60

acgccccagc ggcctggcgc ccatggcagt tcggcagccg ctcaccgata ctcgcgggag      120

gctaacgctc cgggccccgt acccggagag cggcaactcg cgcactcaaa gatggtcccc      180

atccctgctg gagtatttac aatgggcaca gatgatcctc agataaagca ggatggggaa      240

gcacctgcga ggagagttac tattgatgcc ttttacatgg atgcctatga agtcagtaat      300

actgaatttg agaagtttgt gaactcaact ggctatttga cagaggctga gaagtttggc      360

gactcctttg tctttgaagg catgttgagt gagcaagtga agaccaatat tcaacaggca      420

gttgcagctg ctccctggtg gttacctgtg aaaggcgcta actggagaca cccagaaggg      480

cctgactcta ctattctgca caggccggat catccagttc tccatgtgtc ctggaatgat      540

gcggttgcct actgcacttg ggcagggaag cggctgccca cggaagctga gtgggaatac      600

agctgtcgag gaggcctgca taatagactt ttcccctggg gcaacaaact gcagcccaaa      660

ggccagcatt atgccaacat ttggcagggc gagtttccgg tgaccaacac tggtgaggat      720

ggcttccaag gaactgcgcc tgttgatgcc ttccctccca atggttatgg cttatacaac      780

atagtgggga acgcatggga atggacttca gactggtgga ctgttcatca ttctgttgaa      840

gaaacgctta acccaaaagg tcccccttct gggaaagacc gagtgaagaa aggtggatcc      900

tacatgtgcc ataggtctta ttgttacagg tatcgctgtg ctgctcggag ccagaacaca      960

cctgatagct ctgcttcgaa tctgggattc cgctgtgcag ccgaccgcct gcccaccatg     1020

gac                                                                   1023


<210>  5766
<211>  1107
<212>  DNA
<213>  Homo Sapiens

<400>  5766
cgccagaagg agtcaggttc aaaatggaaa gtatttattg accaaattaa caggtctttg       60

gagaattacg aaccatgttc aagtcaaaac tgcagctgct accatggtgt catagaagag      120

gatctaactc ctttccgagg aggcatctcc aggaggatga tggcagaggt agtcagacgg      180

aagctaggga cccactatca gatcactaag aacagactgt accgggaaaa tgactgcatg      240

ttcccctcaa ggtgtagcgg tgttgagcac tttattttgg aagtgatcgg gcgtctccct      300

gacatggaga tggtgatcaa tgtacgagat tatcctcagg ttcctaaatg gatggagcct      360

gccatcccag tcttctcctt cagtaagaca tcagagtacc atgatatcat gtatcctgct      420

tggacatttt gggaaggggg acctgctgtt tggccaattt atcctacagg tcttggacgg      480

tgggacctct tcagagaaga tctggtaagg tcagcagcac agtggccatg gaaaaagaaa      540

aactctacag catatttccg aggatcaagg acaagtccag aacgagatcc tctcattctt      600

ctgtctcgga aaaacacaaa acttgttgat gcagaataca ccaaaaacca ggcctggaaa      660

tctatgaaag ataccttagg aaagccagct gctaaggatg tccatcttgt ggatcactgc      720

aaatacaagt atctgtttaa ttttcgaggc gtagctgcaa gtttccggtt taaacacctc      780

ttcctgtgtg gctcacttgt tttccatgtt ggtgatgagt ggctagaatt cttctatcca      840

cagctgaagc catgggttca ctatatccca gtcaaaacag atctctccaa tgtccaagag      900

ctgttacaat ttgtaaaagc aaatgatgat gtagctcaag agattgctga aaggggaagc      960

cagtttatta ggaaccattt gcagatggat gacatcacct gttactggga gaacctcttg     1020

agtgaatact ctaaattcct gtcttataat gtaacgagaa ggaaaggtta tgatcaaatt     1080

attcccaaaa tgttgaaaac tgaacta                                         1107


<210>  5767
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  5767
gagtccttcg tgaagctttt tattcctaag aggagaaaat cagtcaccgg cgaaatcgtg       60

ctgattacag gagctgggca tggaattggg agactgactg cctatgaatt tgctaaactt      120

aaaagcaagc tggttctctg ggatataaat aagcatggac tggaggaaac agctgccaaa      180

tgcaagggac tgggtgccaa ggttcatacc tttgtggtag actgcagcaa ccgagaagat      240

atttacagct ctgcaaagaa ggtgaaggca gaaattggag atgttagtat tttagtaaat      300

aatgctggtg tagtctatac atcagatttg tttgctacac aagatcctca gattgaaaag      360

acttttgaag ttaatgtact tgcacatttc tggactacaa aggcatttct tcctgcaatg      420

acgaagaata accatggcca tattgtcact gtggcttcgg cagctggaca tgtctcggtc      480

cccttcttac tggcttactg ttcaagcaag tttgctgctg ttggatttca taaaactttg      540

acagatgaac tggctgcctt acaaataact ggagtcaaaa caacatgtct gtgtcctaat      600

ttcgtaaaca ctggcttcat caaaaatcca agtacaagtt tgggacccac tctggaacct      660

gaggaagtgg taaacaggct gatgcatggg attctgactg agcagaagat gatttttatt      720

ccatcttcta tagctttttt aacaacattg gaaaggatcc ttcctgagcg tttcctggca      780

gttttaaaac gaaaaatcag tgttaagttt gatgcagtta ttggatataa aatgaaagcg      840

caa                                                                    843


<210>  5768
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  5768
cgggctctcg agtggttctc ggccgtggta aacatcgagt acgtggaccc gcagaccaac       60

ctgacggtgt ggagcgtctc ggagagtggc cgcttcggcg acagctcgcc caaggagggc      120

gcgcatggcc tggtgggcgt cccgtgggcg cccggcggag acctcgaggg ctgcgcgccc      180

gacacgcgct tcttcgtgcc cgagcccggc ggccgagggg ccgcgccctg ggtcgccctg      240

gtggctcgtg ggggctgcac cttcaaggac aaggtgctgg tggcggcgcg gaggaacgcc      300

tcggccgtcg tcctctacaa tgaggagcgc tacgggaaca tcaccttgcc catgtctcac      360

gcgggaacag gaaatatagt ggtcattatg attagctatc caaaaggaag agaaattttg      420

gagctggtgc aaaaaggaat tccagtaacg atgaccatag gggttggcac ccggcatgta      480

caggagttca tcagcggtca gtct                                             504


<210>  5769
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  5769
cggactgatt caccgagccc aaccgtactc aactcacata tttctacccc aaatgtgaat       60

gctttaacac atgaaaacca aaccaaacct tctatttccc aaatcagcac caccctccct      120

cccacgacga gtaccaagaa aagtggagga gcatctgtgg tccctcatcc ctcgcctact      180

cctctgtctc aagaggaagc tgataacaat gaagatccta gtatagagga ggaggatctt      240

ctcatgctga acagttctcc atccacagcc aaagacactc tagacaatgg cgattatgga      300

gaaccagact atgactggac cacgggcccc agggacgacg acgagtctga tgacaccttg      360

gaagaaaaca ggggttacat ggaaattgaa cagtcagtga aatcttttaa gatgccatcc      420

tcaaatatag aagaggaaga c                                                441


<210>  5770
<211>  975
<212>  DNA
<213>  Homo Sapiens

<400>  5770
attgccgtgg cccaaaaaac ccaagatgga caaaatattg gaatcaagca tattcctgca       60

acccagtgtg gcatttgggt tcgaaccagc aatggaggtc attttgcttc gccaaattat      120

cctgactcat atccaccaaa caaggagtgt atctacattt tggaagctgc tccacgtcaa      180

agaatagagt tgacctttga tgaacattat tatatagaac catcatttga gtgtcggttt      240

gatcacttgg aagttcgaga tgggccattt ggtttctctc ctcttataga tcgttactgt      300

ggcgtgaaaa gccctccatt aattagatca acagggagat tcatgtggat taagtttagt      360

tctgatgaag agcttgaagg actgggattt cgagcaaaat attcatttat tccagatcca      420

gactttactt acctaggagg tattttaaat cccattccag attgtcagtt cgagctctcg      480

ggagctgatg gaatagtgcg ctctagtcag gtagaacaag aggagaaaac aaaaccaggc      540

caagccgttg attgcatctg gaccattaaa gccactccaa aagctaagat ttatttgagg      600

ttcctagatt atcaaatgga gcactcaaat gaatgcaaga gaaacttcgt tgcagtctat      660

gatggaagca gttctattga aaacctgaag gccaagtttt gcagcactgt ggccaatgat      720

gtaatgctta aaacaggaat tggagtgatt cgaatgtggg cagatgaagg tagtcggctt      780

agcaggtttc gaatgctctt tacttccttt gtggagcctc cctgcacaag cagcactttc      840

ttttgccata gcaacatgtg catcaataat tctttagtct gtaatggtgt ccaaaattgt      900

gcataccctt gggatgaaaa tcattgtaaa gaaaagaaaa aagcaggagt atttgaacaa      960

atcactaaga ctcat                                                       975


<210>  5771
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5771
tgggtacatg gggaccccag aagagcagcc tatcctacag acagccaggg ccacttttgt       60

ggccagaagg gcactcccaa tgagaacaag accattttgt tttactttaa cctgttacgc      120

tgtaccagtc cctccgtatt gctaaaccta cagtgcccta ccacacagat ctgtgtctcc      180

aagtgcccag aaaaattttt aacctatgtg gaaatgcaac ttttgtacac aaaagacaaa      240

agctactggg aagactaccg tcagttctgt aagaccactg ctaagcctgt gaagtctctc      300

acacagcttt tactggatga tgattgtcca acagcgattt ttcccagcaa accttttctc      360

cagagatgtt tccctgactt ctctaccaaa aatggcactt taacaatagg aagtaagatg      420

atgtttcaag atggaaatgg agggacaaga agtgttgtag aactcgggat tgctgcaaat      480

ggtatcaata aacttcttga tgcaaagtca cttggattga aagtgtttga agactatgca      540

agaacttgg                                                              549


<210>  5772
<211>  723
<212>  DNA
<213>  Homo Sapiens

<400>  5772
gactcagagg tcatggcgag cacggtggtg aagtacctga gccaggagga ggcccaggcc       60

gtggaccagg agctatttaa cgaataccag ttcagcgtgg accaacttat ggaactggcc      120

gggctgagct gtgctacagc catcgccaag gcatatcccc ccacgtccat gtccaggagc      180

ccccctactg tcctggtcat ctgtggcccg gggaataatg gaggagatgg tctggtctgt      240

gctcgacacc tcaaactctt tggctacgaa ccaaccatct attaccccaa aaggcctaac      300

aagcccctct tcactgcatt ggtgacccag tgtcagaaaa tggacatccc tttccttggg      360

gaaatgcccg cagagcccat gacgattgat gaactgtatg agctggtggt ggatgccatc      420

tttggcttca gcttcaaggg cgatgttcgg gaaccgttcc acagcatcct gagtgtcctg      480

aagggactca ctgtgcccat tgccagcatc gacattccct caggatggga cgtggagaag      540

ggaaatgctg gagggatcca gccagacttg ctcatctccc tcacagcccc caaaaaatct      600

gcaacccagt ttaccggtcg ctaccattac ctggggggtc gttttgtgcc acctgctctg      660

gaaaagaagt accagctgaa cctgccaccc taccctgaca ctgagtgtgt ctatcgtctg      720

cag                                                                    723


<210>  5773
<211>  1185
<212>  DNA
<213>  Homo Sapiens

<400>  5773
ctcgcctctt ggcagcgcaa cgaactgacc gaccggcgct tcctgcagct caataagtgc       60

ccggcgtgct tcggcacgag ctggtgccgc cgcttcctca acgggcaggt ggtattcgag      120

gcgtggggcc gcttgcgcct gctggacttc ctcaacgtga agaacgtgta cttcgcgcag      180

tacggcgagc cccgcgaggg cggccgccgc cgagtggtgc tcaagcgcct cggctcgcag      240

cgcgagctgg cgcagctcga ccagagcatc tgcaagcggg ccaccggccg gccccgctgc      300

gacctgctgc aggccatgcc ccggaccgag ttcgcgcgcc tcaacggcga cgtgcgtctg      360

ctcacgcccg aggcggtgga gggctggtcg gacctggtgc actgcccctc gcagcgcctt      420

ctcgaccgcc tggtgcgccg ctacgcggag accaaggact cgggcagctt cctgcttcgc      480

aacctcaagg actcggagcg catgcagctg ctgctgaccc tggccttcaa ccccgagccg      540

ctggtgctac agagttttcc gtctgatgaa ggttggccat ttgcaaagta tcttggagct      600

tgtggaagaa tggtggctgt aaattatgtt ggagaagaac tgtggagtta ctttaatgcg      660

ccatgggaaa aacgagttga cctcgcttgg caattaatgg aaatagcaga acagcttaca      720

aacaatgact ttgaatttgc actctacctc ctggacgtca gctttgacaa ttttgcagtt      780

ggtcctagag atgggaaggt aatcattgtg gatgctgaaa atgttttggt tgctgacaaa      840

agattaatta gacaaaataa acctgaaaat tgggatgtat ggtatgaaag caagtttgat      900

gactgtgata aggaggcttg cttatcattt tcaaaagaaa ttctttgtgc tcgtgccact      960

gtggaccaca attactatgc tgtttgtcag aacctcttat ccagacatgc cacctggcgt     1020

ggcacttctg gaggactcct tcatgatcca ccaagtgaaa ttgccaaaga tggccggctc     1080

gaggccttgc tggatgagtg tgccaaccca aagaagcgct atggcagatt ccaggctgca     1140

aaagaactgc gtgaatacct agcacaatta agtaacaacg tgagg                     1185


<210>  5774
<211>  144
<212>  DNA
<213>  Homo Sapiens

<400>  5774
atgaattata cagagtccag cccattgaga gaatcaactg ccataggttt tacacctgag       60

ttagaaagta tcatacctgt gccttccaat aagaccactt gtgaaaactg gagagagata      120

catcatctgg tttttcatgt agca                                             144


<210>  5775
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  5775
ctccatccca ctggaaacat aacaggctta ccaggcagta aacggtcaca accacccaga       60

aacatcacca aagagcccaa agtgttcttt cataaaaccc agttgcctgg gattcaaggg      120

gctgcctcga gatccacggc tgcatcccct acgaacccca tgaaattcct gaggaataaa      180

gcaataattc ggcatagacc tgctcttgtt aaa                                   213


<210>  5776
<211>  1554
<212>  DNA
<213>  Homo Sapiens

<400>  5776
caggattcga ctcaggcctc cactccaggc agccctctct ctcctaccga atacgaacgc       60

ttcttcgcac tgctgactcc aacctggaag gcagagacta cctgccgtct ccgtgcaacc      120

cacggctgcc ggaatcccac actcgtccag ctggaccaat atgaaaacca cggcttagtg      180

cccgatggtg ctgtctgctc caacctccct tatgcctcct ggtttgagtc tttctgccag      240

ttcactcact accgttgctc caaccacgtc tactatgcca agagagtcct gtgttcccag      300

ccagtctcta ttctctcacc taacactctc aaggagatag aagcttcagc tgaagtctca      360

cccaccacga tgacctcccc catctcaccc cacttcacag tgacagaacg ccagaccttc      420

cagccctggc ctgagaggct cagcaacaac gtggaagagc tcctacaatc ctccttgtcc      480

ctgggaggcc aggagcaagc gccagagcac aagcaggagc aaggagtgga gcacaggcag      540

gagccgacac aagaacacaa gcaggaagag gggcagaaac aggaagagca agaagaggaa      600

caggaagagg agggaaagca ggaagaagga caggggacta aggagggacg ggaggctgtg      660

tctcagctgc agacagactc agagcccaag tttcactctg aatctctatc ttctaaccct      720

tcctcttttg ctccccgggt acgagaagta gagtctactc ctatgataat ggagaacatc      780

caggagctca ttcgatcagc ccaggaaata gatgaaatga atgaaatata tgatgagaac      840

tcctactgga gaaaccaaaa ccctggcagc ctcctgcagc tgccccacac agaggccttg      900

ctggtgctgt gctattcgat cgtggagaat acctgcatca taacccccac agccaaggcc      960

tggaagtaca tggaggagga gatccttggt ttcgggaagt cggtctgtga cagccttggg     1020

cggcgacaca tgtctacctg tgccctctgt gacttctgct ccttgaagct ggagcagtgc     1080

cactcagagg ccagcctgca gcggcaacaa tgcgacacct cccacaagac tccctttgtc     1140

agccccttgc ttgcctccca gagcctgtcc atcggcaacc aggtagggtc cccagaatca     1200

ggccgctttt acgggctgga tttgtacggt gggctccaca tggacttctg gtgtgcccgg     1260

cttgccacga aaggctgtga agatgtccga gtctctgggt ggctccagac tgagttcctt     1320

agcttccagg atggggattt ccctaccaag atttgtgaca cagactatat ccagtaccca     1380

aactactgtt ccttcaaaag ccagcagtgt ctgatgagaa accgcaatcg gaaggtgtcc     1440

cgcatgagat gtctgcagaa tgagacttac agtgcgctga gccctggcaa aagtgaggac     1500

gttgtgcttc gatggagcca ggagttcagc accttgactc taggccagtt cgga           1554


<210>  5777
<211>  177
<212>  DNA
<213>  Homo Sapiens

<400>  5777
gaagacggga agaatgactc cctgccgtct gagtccacgt cgcacaggtg gcgggggcct       60

gcctgcaggc cccccgatag ctcctacaac agcctgtact ccacctgcct ggagctgttc      120

aagttcacca tcggcatggg cgacctggag ttcactgaga actatgactt caaggct         177


<210>  5778
<211>  275
<212>  DNA
<213>  Homo Sapiens

<400>  5778
tctcgccagg actgaagtgt gtatgtcttt tgtgtgattc ttcaaacttt acctgccaaa       60

cagaaggagc atgttgggca tcagtcatgc taaccaatgg aaaagagcag gtgatcaaat      120

cctgtgtctc ccttccagaa ctgaatgctc aagtcttctg tcatagttcc aacaatgtta      180

ccaaaaccga atgctgcttc acagattttt gcaacaacat aacactgcac cttccaacag      240

catcaccaaa tgccccaaaa cttggaccca tggag                                 275


<210>  5779
<211>  153
<212>  DNA
<213>  Homo Sapiens

<400>  5779
aaattcaagg agatctgtga acgtccaaat ggctcctgtc gggacttttg ccttgaaaca       60

gaaatccatg ttgggagatg tttaaatagc caaccctgct gcctgcctct ggggcatcaa      120

ccaagaattg agagcactac acccaaaaag gac                                   153


<210>  5780
<211>  198
<212>  DNA
<213>  Homo Sapiens

<400>  5780
agcttctgga acaaagatcc ctttctagat atgataagag aaactgagca gtgctgggta       60

cagcctccat ataagtactg tgagaaaagg tgtactaaaa taatgacttg tgtacgtcca      120

aatcatacat gctgctggac ctactgtgga aacatctgct tagacaacga agagcccctt      180

aaatcaatgc taaacccc                                                    198


<210>  5781
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  5781
gaaatgagga agaaaagata tgacaggaag gaattgttac ttgaagaatg ctggggaaag       60

ccaaatgtca aagaatgtac caataagtgt tctaaagcct ttagatgtaa agacaaaaat      120

tacacatgct gctggaccta ttgtggaaac atctgctgga taaacgtcga aaccagtgga      180

gattac                                                                 186


<210>  5782
<211>  774
<212>  DNA
<213>  Homo Sapiens

<400>  5782
aggaagtctg cagcctgcgg gcagccccgc atgtccagtc ggatcgttgg gggccgggat       60

ggccgggacg gagagtggcc gtggcaggcg agcatccagc atcgtggggc acacgtgtgc      120

ggggggtcgc tcatcgcccc ccagtgggtg ctgacagcgg cgcactgctt ccccaggagg      180

gcactgccag ctgagtaccg cgtgcgcctg ggggcgctgc gtctgggctc cacctcgccc      240

cgcacgctct cggtgcccgt gcgacgggtg ctgctgcccc cggactactc cgaggacggg      300

gcccgcggcg acctggcact gctgcagctg cgtcgcccgg tgcccctgag cgctcgcgtc      360

caacccgtct gcctgcccgt gcccggcgcc cgcccgccgc ccggcacacc atgccgggtc      420

accggctggg gcagcctccg cccaggagtg cccctcccag agtggcgacc gctacaagga      480

gtaagggtgc cgctgctgga ctcgcgcacc tgcgacggcc tctaccacgt gggcgcggac      540

gtgccccagg ctgagcgcat tgtgctgcct gggagtctgt gtgccggcta cccccagggc      600

cacaaggacg cctgccaggg tgattctggg ggacctctga cctgcctgca gtctgggagc      660

tgggtcctgg tgggcgtggt gagctggggc aagggttgtg ccctgcccaa ccgtccaggg      720

gtctacacca gtgtggccac atatagcccc tggattcagg ctcgcgtcag cttc            774


<210>  5783
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  5783
atggcagccc agaatggaaa caccagtttc acacccaact ttaatccacc ccaagaccat       60

gcctcctccc tctcctttaa cttcagttat ggtgattatg acctccctat ggatgaggat      120

gaggacatga ccaagacccg gaccttcttc gcagccaaga tc                         162


<210>  5784
<211>  1305
<212>  DNA
<213>  Homo Sapiens

<400>  5784
gaccctgggg cactgctgcg gttgggcatg gacatcatga accaggtcca gagcgccatg       60

gatgagagtc atatcctgga gaagatggca gccgaggcag gcaagaaaca gccagggatg      120

aaacctatca agggcatcac caatttgaag gtgaaggatg tccagctgcc cgtcatcaca      180

ctgaactttg tacctggagt gggcatcttc caatgtgtgt ccacaggcat gaccgtcact      240

ggcaagagct tcatgggagg gaacatggag atcatcgtgg ccctgaacat cacagccacc      300

aaccggcttc tgcgggatga ggagacaggc ctccccgtgt tcaagagtga gggctgtgag      360

gtcatcctgg tcaatgtgaa gactaacctg cctagcaaca tgctccccaa gatggtcaac      420

aagttcctgg acagcaccct gcacaaagtc ctccctgggc tgatgtgtcc cgccatcgat      480

gcagtcctgg tgtatgtgaa caggaagtgg accaacctca gtgaccccat gcctgtgggc      540

cagatgggca ccgtcaaata tgttctgatg tccgcaccag ccaccacagc cagctacatc      600

caactggact tcagtcctgt ggtgcagcag caaaagggca aaaccatcaa gcttgctgat      660

gccggggagg ccctcacgtt ccctgagggt tatgccaaag gctcgtcgca gctgctgctc      720

ccagccacct tcctctctgc agagcttgcc cttctgcaga agtcctttca tgtgaatatc      780

caggatacaa tgattggtga gctgccccca caaaccacca agaccctggc tcgcttcatt      840

cctgaagtgg ctgtagctta tcccaagtca aagcccttga cgacccagat caagataaag      900

aagcctccca aggtcactat gaagacaggc aagagcctgc tgcacctcca cagcaccctg      960

gagatgttcg cagctcggtg gcggagcaag gctccaatgt ccctctttct cctagaagtg     1020

cacttcaatc tgaaggtcca gtactcagtg cacgagaacc agctgcagat ggccacttct     1080

ttggacagat tactgagctt gtcccggaag tcctcatcga ttggcaactt caatgagagg     1140

gaattaactg gcttcatcac cagctatctc gaagaagcct acatcccagt tgtcaatgat     1200

gtgcttcaag tggggctccc actcccggac tttctggcca tgaattacaa tctggctgag     1260

ctggacatag tagagaatgc cctgatgctg gacttgaagc tgggc                     1305


<210>  5785
<211>  204
<212>  DNA
<213>  Homo Sapiens

<400>  5785
ttcccagtct ctcaagacca ggaacgagaa aaaagaagta tcagtgacag cgatgaatta       60

gcttcagggt tttttgtgtt cccttaccca tatccatttc gcccacttcc accaattcca      120

tttccaagat ttccatggtt tagacgtaat tttcctattc caatacctga atctgcccct      180

acaactcccc ttcctagcga aaag                                             204


<210>  5786
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  5786
tactttaggg gatacaagcc aagatccaca gatttgattc tcaggcacct gactgtagct       60

gactccttgg ttatcctatc taaaagaatc ccagagacca tggcaacttt tgggttgaaa      120

cattttgaca attattttgg atgcaaattt cttttgtatg cacacagg                   168


<210>  5787
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  5787
gaggagcctg cagccagctt ctcccaaccc ggcagcatgg gcctggataa gaacacagtg       60

cacgaccaag agcatatcat ggagcatcta gaaggtgtca tcaacaaacc agaggcggag      120

atgtcgccac aagaattgca gctccattac ttcaaaatgc atgattatga tggcaataat      180

ttgcttgatg gcttagaact ctccacagcc atcactcatg tccataagga ggaagggagt      240

gaacaggcac cactaatgag tgaagatgaa ctgattaaca taatagatgg tgttttgaga      300

gatgatgaca agaacaatga tggatacatt gactatgctg aatttgcaaa atcactgcag      360


<210>  5788
<211>  549
<212>  DNA
<213>  Homo Sapiens

<400>  5788
gaagcatcag aaagcacaat gaagataatt aaagaagaat ttacagacga agagatgcaa       60

tatgacatgg caaaaagtgg ccaagaaaaa cagaccattg agatattaat gaacccgatc      120

ctgttagtta aaaataccag cctcagcatg tccaaggatg atatgtcttc cacattactg      180

acattcagaa gtttacatta taatgacccc aagggaaaca gttcgggtaa tgacaaagag      240

tgttgcaatg acatgacagt ctggagaaaa gtttcagaag caaacggatc gtgcaagtgg      300

agcaataact tcatccgcag ctccacagaa gtgatgcgca gggtccacag ggcccccagc      360

tgcaagtttg tacagaatcc tggcataagc tgctgtgaga gcctagaact ggaaaataca      420

gtgtgccagt tcactacagg caaacaattc cccaggtgcc aataccatag tgttacctca      480

ttagagaaga tattgacagt gctgacaggt cattctctga tgagctggtt agtttgtggc      540

tctaagttg                                                              549


<210>  5789
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  5789
cagccctact ggatcggcga cagcgtcaac acaccgcagg caggctactt cggccttttc       60

tcctactgcg tgggtaacgt gctgtcctcc gagctcatct gcaagggcgg ccccctagac      120

ttctcctcca tcccctctag agccttcaag actgccatgt tc                         162


<210>  5790
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  5790
tacttcgatg gccccctcta cccagagatg tccaatggga ctctgcacca ctacttcgtg       60

cccgatgggg actatgagga gaacgatgac cccgagaagt gccagctgct cttcagggtg      120

agtgaccaca ggcgctgctc ccagggggag gggagccagg ttggcagcct gctgagcctc      180

accctgcggg aggagttcac cgtgctgggc cgccaggtgg aggatgctgg gcgcgtgctg      240

gagggcatca gcaaaagcat ctcctacgac ctagacgggg aagagagcta tggcaagtac      300

ctgcggcggg agtcccacca gatcggggat gcctactcca actcggacaa atccctcact      360

gagctggaga gcaagttcaa gcagggccag gaacaggaca gccggcagga gagcaggctc      420

aacgaggact ttctgggaat gctggtccac accaggtccc tgctgaagga gacactggac      480

atctctgtgg ggctcaggga caaatacgag ctgctggccc tcaccattag gagccatggg      540

acccgactag gtcggctgaa aaatgattat cttaaagta                             579


<210>  5791
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  5791
gccatcagct gggagctgga caacgtgctg atgcctagtc ccagaatctg gccccaggtg       60

actccaacag gcaggtctgc ctctgtcagg agtgagggta acacctcctc actctggaat      120

ttctcagctg ggcaggatgt gcatgccata gtaaccagaa cctgtgagtc tgtgctgagc      180

tctgccgtct acacccacgg ctgtggctgt gtgaggtctg ccacaaacat tacctgtcag      240

tcctcaggac aacaaaggca ggcggcccgg caggaagagg agaactcaat ctgcaaggcc      300

catgatagta gagagggccg cctgggctac cccctcagtg cccatcagcc tggttccggt      360

ggtcctaac                                                              369


<210>  5792
<211>  1065
<212>  DNA
<213>  Homo Sapiens

<400>  5792
cgagaaaggg atcatgaact acgtcacaga aggcatcatc accaatcacc caaatctcac       60

tttgaattac cacattatcc tggactgcta gctcaccaga agccgttcat tagaaagtcc      120

tataaatgtc tgcacaaacg ctgtaggcct aagcttccac cttcacctaa taaccccccc      180

aaattcccaa atcctcacca gccacctaaa catccagata aaaatagcag tgtggtcaac      240

cctaccttag tggctacaac ccaaattcca tctgtgactt tcccatcagc ttccaccaaa      300

attactaccc ttccaaatgt gacttttctt ccccagaatg ccaccaccat atcttcaaga      360

gaaaatgtta acacaagctc ttctgtagct acattagcac cagtgaattc cccagctcca      420

caagacacca cagctgcccc acccacacct tctgcaacta caccagctcc accatcttcc      480

tcagctccac cagagaccac agctgcccca cccacacctt ctgcaactac acaagctcca      540

ccatcttcct cagctccacc agagaccaca gctgccccac ccacacctcc tgcaactaca      600

ccagctccac catcttcctc agctccacca gagaccacag ctgccccacc cacaccttct      660

gcaactacac cagctccact atcttcctca gctccaccag agaccacagc tgtcccaccc      720

acaccttctg caactaccct agacccatca tccgcctcag ctccaccaga gaccacagct      780

gccccaccca caccttctgc aactacacca gctccaccgt cttccccagc tccacaagag      840

accacagctg ccccaattac cacacctaat tcttccccaa ctactcttgc acctgacact      900

tctgaaactt cagctgcacc cacacaccag actattactt cggtcactac tcaaactact      960

actactaaac aaccaacttc agctcctggc caaaataaaa tttctcgatt tcttttatat     1020

atgaagaatc tactaaacag aattattgac gacatggtgg agcaa                     1065


<210>  5793
<211>  2226
<212>  DNA
<213>  Homo Sapiens

<400>  5793
atgcctgctg gagggaaagg aagccatcct tcatctacac cccagagggt ccccaaccgc       60

ctgatccacg agaagtcacc atacctccta caacatgcct acaatcctgt ggactggtac      120

ccctggggag aggaagcctt cgacaaggcc aggaaggaaa acaagccgat tttcctctca      180

gtcgggtact ccacctgcca ctggtgccac atgatggaag aggagtcctt ccagaatgag      240

gagattggcc gcctgctcag tgaggacttt gtgagtgtga aggtagaccg tgaggagcgg      300

cctgacgtgg acaaggtgta catgacgttc gtgcaggcca ccagcagcgg cgggggctgg      360

cccatgaatg tgtggctgac tcccaacctc cagccctttg tcgggggcac ctatttccct      420

cctgaggatg gcttgacccg agtcggcttc cgcacagtgt tgctgagaat acgagaacag      480

tggaaacaga acaagaacac cctgctagaa aatagccagc gtgtcaccac tgccctgctg      540

gcccgatcag agatcagcgt gggtgaccgc cagctgccgc cctctgccgc caccgtgaac      600

aatcgctgct tccagcagct ggatgagggc tatgatgagg aatacggtgg cttcgctgag      660

gcccccaagt ttcccacgcc ggtgatcctg agcttcctgt tctcctactg gctcagccat      720

cgactgactc aggatggctc tcgggcccag cagatggcct tgcataccct gaaaatgatg      780

gctaacgggg gcatccggga ccatgtgggg cagggctttc accgctactc cacagaccgc      840

cagtggcacg tccctcactt tgagaagatg ctctatgacc aggcacagct cgctgtggcc      900

tattcgcagg ccttccagct ctctggtgat gaattctact ctgacgtggc caaaggcatc      960

ctgcagtacg tggctcggag cctgagccac cggtccggag gcttctatag cgcagaggat     1020

gcagactcgc ccccagagcg gggccagcgg cccaaagagg gcgcctacta tgtgtggacg     1080

gtcaaagagg ttcagcagct cctcccggag cctgtgttgg gtgccaccga gccgctgacc     1140

tcaggccagc tcctcatgaa gcactacggc ctcacagagg ctggtaacat cagccccagt     1200

caggacccca agggggagct gcagggccag aatgtgctga ccgtccggta ctcgctggag     1260

ctgactgctg cccgctttgg cttggatgtg gaggccgtgc ggaccttgct caatacaggg     1320

ctggagaagc tcttccaggc ccggaagcat cggcccaagc cgcacctgga cagcaagatg     1380

ctggctgcct ggaatggctt gatggtgtca ggctatgctg tgactggggc tgtcctgggc     1440

caagacaggc tgatcaacta tgccaccaat ggtgccaagt tcctgaagcg gcacatgttt     1500

gatgtggcca gtggccgcct gatgcggacc tgctacaccg gccctggggg gactgtggag     1560

cacagcaacc caccctgctg gggcttcctg gaggactacg ccttcgtggt gcggggcctg     1620

ctggacctgt atgaggcctc acaggagagt gcgtggctcg agtgggctct gcggctgcag     1680

gacacacagg acaggctctt ttgggactcc cagggtggcg gctacttctg cagtgaggct     1740

gagctggggg ctggcctgcc cctgcgtctg aaggacgacc aggatggagc agagcccagc     1800

gccaattccg tgtcagccca caacctgctc cggctgcatg gcttcacggg ccacaaggac     1860

tggatggaca agtgtgtgtg cctattgacc gccttttccg agcgcatgcg tcgtgtcccg     1920

gtggcgttgc ccgagatggt ccgcgccctc tcagcccagc agcagaccct caagcagatc     1980

gtgatctgtg gagaccgtca ggccaaggac accaaggccc tggtgcagtg cgtccactct     2040

gtctacattc ctaacaaggt gctgattctg gctgatgggg acccctcgag cttcctgtcc     2100

cgccagctgc ctttcctgag taccctccga cggttggaag accaggccac tgcatatgtg     2160

tgtgagaatc aagcctgctc agtgcccatc actgatccct gcgaattacg aaaactacta     2220

catcca                                                                2226


<210>  5794
<211>  1599
<212>  DNA
<213>  Homo Sapiens

<400>  5794
ctgcacaacg tcacggccga gctctttggg gccgaggcct ggggcaccct tgcggctttc       60

ggggacctca actccgacaa gcagacggat ctcttcgtgc tgcgggaaag aaatgactta      120

atcgtctttt tggcagacca gaatgcaccc tattttaaac ccaaagtaaa ggtatctttc      180

aagaatcaca gtgcattgat aacaagtgta gtccctgggg attatgatgg agattctcaa      240

atggatgtcc ttctgacata tcttcccaaa aattatgcca agagtgaatt aggagctgtt      300

atcttctggg gacaaaatca aacattagat cctaacaata tgaccatact caataggact      360

tttcaagatg agccactaat tatggatttc aatggtgatc taattcctga tatttttggt      420

atcacaaatg aatccaacca gccacagata ctattaggag ggaatttatc atggcatcca      480

gcattgacca ctacaagtaa aatgcgaatt ccacattctc atgcatttat tgatctgact      540

gaagatttta cagcagattt attcctgacg acattgaatg ccaccactag taccttccag      600

tttgaaatat gggaaaattt ggatggaaac ttctctgtca gtactatatt ggaaaaacct      660

caaaatatga tggtggttgg acagtcagca tttgcagact ttgatggaga tggacacatg      720

gatcatttac tgccaggctg tgaagataaa aattgccaaa agagtaccat ctacttagtg      780

agatctggga tgaagcagtg ggttccagtc ctacaagatt tcagcaataa gggcacactc      840

tggggctttg tgccatttgt ggatgaacag caaccaactg aaataccaat tccaattacc      900

cttcatattg gagactacaa tatggatggc tatccagacg ctctggtcat actaaagaac      960

acatctggaa gcaaccagca ggccttttta ctggagaacg tcccttgtaa taatgcaagc     1020

tgtgaagagg cgcgtcgaat gtttaaagtc tactgggagc tgacagacct aaatcaaatt     1080

aaggatgcca tggttgccac cttctttgac atttacgaag atggaatctt ggacattgta     1140

gtgctaagta aaggatatac aaagaatgat tttgccattc atacactaaa aaataacttt     1200

gaagcagatg cttattttgt taaagttatt gttcttagtg gtctgtgttc taatgactgt     1260

cctcgtaaga taacaccctt tggagtgaat caacctggac cttatatcat gtatacaact     1320

gtagatgcaa atgggtatct gaaaaatgga tcagctggcc aactcagcca atccgcacat     1380

ttagctctcc aactaccata caacgtgctt ggtttaggtc ggagcgcaaa ttttcttgac     1440

catctctacg ttggtattcc ccgtccatct ggagaaaaat ctatacgaaa acaagagtgg     1500

actgcaatca ttccaaattc ccagctaatt gtcattccat accctcacaa tgtccctcga     1560

agttggagtg ccaaactgta tcttacacca agtaatatt                            1599


<210>  5795
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5795
ctggcagtcc tgctgcaggc agccgaggcc gcgccaggtc ttgggcctcc tgaccctaga       60

ccacggacat taccgccgct gccaccgggc cctacccctg cccagcagcc gggccgtggt      120

ctggctgaag ctgcggggcc gcggggctcc gagggaggca atggcagcaa ccctgtggcc      180

gggcttgaga cggacgatca cggagggaag gccggggaag gctcggtggg tggcggcctt      240

gctgtgagcc ccaaccctgg cgacaagccc atgacccagc gg                         282


<210>  5796
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  5796
atggccaacc acaacctgct gcagatcttc acagccgcca cccctgtcca ccactgtcgc       60

ccgccccaca atgcctccac agggccttgg gtgctcccca tgggcccaaa tgggaagcct      120

gagaggtgcc tccgttttgt acatccgccc aatgccagcc tgcccaatga cacccagagg      180

gccatggagc catgcctgga tggctgggtc tacaacagca ccaaggactc cattgtgaca      240

gagtgggact tggtgtgcaa ctccaacaaa ctgaaggag                             279


<210>  5797
<211>  1539
<212>  DNA
<213>  Homo Sapiens

<400>  5797
atgactcctg aatcaaggga tactacagat ttgtctccag ggggtaccca ggagatggaa       60

ggcatcgtga tagtgaaggt ggaggaggaa gatgaagaag accattttca aaaggaaaga      120

aacaaagtag agtcatcgcc acaagttctc agtcgctcta caactatgaa tgagagagcc      180

ttattgtcat cgtatttagt tgcatataga gtggcaaaag agaaaatggc tcacacagcg      240

gctgaaaaaa ttatccttcc agcatgtatg gacatggtac ggacaatttt tgatgacaaa      300

tcagctgata aactaagaac tatacctctt agtgataata caatatctcg tcgaatctgt      360

acgattgcaa aacatttgga agcaatgctt attacacggc tgcagtccgg tatagacttt      420

gcaatccaac tcgatgagag cactgatatt gcaagttgtc ccacactctt ggtttatgtc      480

agatatgtgt ggcaagatga ttttgtagag gatctcttat gttgtttaaa tttaaattca      540

catataactg gattagattt atttactgaa ttagaaaact gccttcttgg tcagtataaa      600

ttaaactgga aacattgtaa aggaatttca agtgatggaa cagcaaatat gaccggaaaa      660

cacagcagac ttactgaaaa attgttagaa gcaacccaca acaatgctgt ttggaatcac      720

tgttttattc atcgagaagc tttggtatcc aaagaaattt caccaagtct gatggatgta      780

ttgaaaaatg cagtgaaaac tgttaatttt attaaaggaa gctcactgaa tagccgactt      840

ctcgaaatat tttgttcaga gattggagtg aaccacaccc acttattgtt tcatacagaa      900

gttcgttggc tttctcaagg aaaagtattg agcagagtat atgaactcag gaacgagatt      960

tacatttttc tcgttgaaaa gcaatctcat ttggcaaata tttttgaaga cgacatttgg     1020

gtaacaaaat tggcatattt aagtgatatt tttggcattc ttaatgaatt aagcctgaaa     1080

atgcagggga aaaacaatga tatatttcag tatcttgaac atattctagg attccaaaag     1140

acgttattat tgtggcaagc aagacttaaa agtaaccgcc ctagctacta tatgtttcca     1200

acattattgc aacacatcga agagaacatt attaatgaag actgcttaaa agaaataaaa     1260

ttagagatat tgttgcatct cacttctttg tctcaaactt ttaattatta ctttccggaa     1320

gagaaatttg aatcattaaa ggaaaatatt tggatgaaag atccatttgc ttttcaaaac     1380

ccagaatcaa taattgagtt aaacttggag cctgaagaag agaatgaatt attgcagctc     1440

agttcatcat tcacactaaa gaattattat aagatattaa gtttatcagc attttggatt     1500

aagattaaag atgactttcc actgctaagt aggaagagt                            1539


<210>  5798
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  5798
cagttcaacg gctacaactg tgatgccaac ctccacagta gatttcctgc tgagagagac       60

atcagtgtct attgtggagt gcaggctatt acgatgaaga ttaatttttg cacggtactt      120

ttctcgggtt attcggaaac agatctggca ctgaatggaa ggcatgggga ctcccactgc      180

agagggttca tcaataacaa cacctttcca gcagtggtca tttttatcat caatctcagc      240

accttggagg gctgtggaaa caacctggtg gtatccacaa ttcctggagt cagtgcttat      300

ggaaatgcaa cttcagtgca agtaggaaat atttcaggat atattgatac tccagaccca      360

ccaacaatca tcagctatct acctgggctt ctttacaaat ttagttgtag ttatccattg      420

gaatacctgg ttaataatac ccagcttgct tcgtcctcag cggctatttc tgtgagagag      480

aacaatggca catttgtcag cactttgaac ctgctccttt ataacgattc aacctacaac      540

cagcagttaa ttatccccag tataggatta cctttgaaaa ccaaagtatt tgcagctgtc      600

caagccacta atttggatgg cagatggaat gttttaatgg attattgcta tactacccca      660

tcaggaagcc caaatgatga cattcgatat gatcttttcc ttagctgtga caaggaccct      720

cagaccaccg tcattgagaa tggccgaagc cagcggggcc ggttttcttt tgaagtgttc      780

cgatttgtga aacacaagaa tcagaaaatg tccactgtct tcttgcactg cgttaccaag      840

ctctgcagag cagatgactg ccccttcctt atgccgattt gcagccacag agaaaggaga      900


<210>  5799
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  5799
atggagacca ccatggggtt catggatgac aatgccacca acacttccac cagcttcctt       60

tctgtgctca accctcatgg agcccatgcc acttccttcc cattcaactt cagctacagc      120

gactatgata tgcctttgga tgaagatgag gatgtgacca attccaggac gttctttgct      180

gccaag                                                                 186


<210>  5800
<211>  480
<212>  DNA
<213>  Homo Sapiens

<400>  5800
gactttgatg attttaacct ggaggatgca gtgaaagaaa cttcctcagt aaagcagcca       60

tgggaccaca ccaccaccac cacaaccaat aggccaggaa ccaccagagc tccggcaaaa      120

cctccaggta gtggattgga cttggctgat gctttggatg atcaagatga tggccgcagg      180

aaaccgggta taggaggaag agagagatgg aaccatgtaa ccaccacgac caagaggcca      240

gtaaccacca gagctccagc aaatacttta ggaaatgatt ttgacttggc tgatgccctg      300

gatgatcgaa atgatcgaga tgatggccgc aggaaaccaa ttgctggagg aggaggtttt      360

tcagacaagg atcttgaaga catagtaggg ggtggagaat acaaacctga caagggtaaa      420

ggtgatggcc ggtacggcag caatgacgac cctggatctg gcatggtggc agagcctggc      480


<210>  5801
<211>  435
<212>  DNA
<213>  Homo Sapiens

<400>  5801
attgcaataa aaaaggaaaa gaggcctcct cagacactct caagaggatg gggagatgac       60

atcacttggg tacaaactta tgaagaaggt ctcttttatg ctcaaaaaag taagaagcca      120

ttaatggtta ttcatcacct ggaggattgt caatactctc aagcactaaa gaaagtattt      180

gcccaaaatg aagaaataca agaaatggct cagaataagt tcatcatgct aaaccttatg      240

catgaaacca ctgataagaa tttatcacct gatgggcaat atgtgcctag aatcatgttt      300

gtagaccctt ctttaacagt tagagctgac atagctggaa gatactctaa cagattgtac      360

acatatgagc ctcgggattt acccctattg atagaaaaca tgaagaaagc attaagactt      420

attcagtcag agcta                                                       435


<210>  5802
<211>  585
<212>  DNA
<213>  Homo Sapiens

<400>  5802
cactctcttt gcttcaactt cactataaaa tcattgtcca gacctggaca gccctggtgt       60

gaagcgcagg tcttcttgaa taaaaatctt ttccttcagt acaacagtga caacaacatg      120

gtcaaacctc tgggcctcct ggggaagaag gtaaatgcca ccagcacttg gggagagttg      180

acccaaacgc tgggagaagt ggggcgagac ctcaggatgc tcctttgtga catcaaaccc      240

cagataaaga ccagtgatcc ttccactctg caagtcgaga tgttttgtca acatgaagca      300

gaacggtgca ctggtgcatc ctggcagttc accatcaatg gagagaaatc cctcctcttt      360

gacgcaatga acatgacctg gacagtaatt aatcatgaag ccagtaagat caaggagaca      420

tggaagaaag acagagggct ggaaaagtat ttcaggaagc tctcaaaggg agactgcgat      480

cactggctca gggaattctt agggcactgg gaggcaatgc cagaaccgac agtgtcacca      540

gtaaatgctt cagatatcca ctggtcttct tctagtctac cagat                      585


<210>  5803
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  5803
aacatccaca tgaacttcac ccatatctgc agaagccaca attctatcaa ccagtccttg       60

gatgagtctg tgatttatgg accaggaaac ctgtcaacca acaacaatac tctcagagac      120

cacttcaaag ggatttcttc ccatagcaga agctcactca tgcccctgag aaatgatgtg      180

gataagagag gggagacgac ctcagcatcc ttgctaaatg ctggattaag ccacactgaa      240

taccagatag tcacagaccc tggggacgtc ccagcttttt tgaaatggct gtccttagcc      300


<210>  5804
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5804
aagcccaagg acatgacatc atctcagtgg tttaaaactc agcatgtgca gcccagccct       60

caagcatgca actcagccat gagcatcatc aataagtaca cagaacggtg caaagacctc      120

aacaccttcc tgcacgagcc cttctccagt gtggccatca cctgccagac ccccaacata      180

gcctgcaaga atagctgtaa aaactgccac cagagccacg ggcccatgtc cctgaccatg      240

ggtgagctca cctcagggaa gtacccaaac tgcaggtaca aagagaagca cctgaacaca      300

ccttacatag tggcctgtga ccctccacaa cagggtgacc cagggtaccc acttgttcct      360

gtgcacttgg ataaagttgt c                                                381


<210>  5805
<211>  1389
<212>  DNA
<213>  Homo Sapiens

<400>  5805
accctcagtc ccactgcagt tctcatcctc ggcccaaaag tcatcaaaga aaagctgaca       60

caggagctga aggaccacaa cgccaccagc atcctgcagc agctgccgct gctcagtgcc      120

atgcgggaaa agccagccgg aggcatccct gtgctgggca gcctggtgaa caccgtcctg      180

aagcacgtca tctggctgaa ggtcatcaca gctaacatcc tccagctgca ggtgaagccc      240

tcggccaatg accaggagct gctagtcaag atccccctgg acatggtggc tggattcaac      300

acgcccctgg tcaagaccat cgtggagttc cacatgacga ctgaggccca agccaccatc      360

cgcatggaca ccagtgcaag tggccccacc cgcctggtcc tcagtgactg tgccaccagc      420

catgggagcc tgcgcatcca actgctgcat aagctctcct tcctggtgaa cgccttagct      480

aagcaggtca tgaacctcct agtgccatcc ctgcccaatc tagtgaaaaa ccagctgtgt      540

cccgtgatcg aggcttcctt caatggcatg tatgcagacc tcctgcagct ggtgaaggtg      600

cccatttccc tcagcattga ccgtctggag tttgaccttc tgtatcctgc catcaagggt      660

gacaccattc agctctacct gggggccaag ttgttggact cacagggaaa ggtgaccaag      720

tggttcaata actctgcagc ttccctgaca atgcccaccc tggacaacat cccgttcagc      780

ctcatcgtga gtcaggacgt ggtgaaagct gcagtggctg ctgtgctctc tccagaagaa      840

ttcatggtcc tgttggactc tgtgcttcct gagagtgccc atcggctgaa gtcaagcatc      900

gggctgatca atgaaaaggc tgcagataag ctgggatcta cccagatcgt gaagatccta      960

actcaggaca ctcccgagtt ttttatagac caaggccatg ccaaggtggc ccaactgatc     1020

gtgctggaag tgtttccctc cagtgaagcc ctccgccctt tgttcaccct gggcatcgaa     1080

gccagctcgg aagctcagtt ttacaccaaa ggtgaccaac ttatactcaa cttgaataac     1140

atcagctctg atcggatcca gctgatgaac tctgggattg gctggttcca acctgatgtt     1200

ctgaaaaaca tcatcactga gatcatccac tccatcctgc tgccgaacca gaatggcaaa     1260

ttaagatctg gggtcccagt gtcattggtg aaggccttgg gattcgaggc agctgagtcc     1320

tcactgagca aggatgccct tgtgcttact ccagcctcct tgtggaaacc cacctctcct     1380

gtctcccag                                                             1389


<210>  5806
<211>  255
<212>  DNA
<213>  Homo Sapiens

<400>  5806
tgtccgcgcc gcttcctgga ggagctgggc tactggggcg tgcggctcaa gtacacgcca       60

cgctgctgcc gcatctgctt cgaggagcgg cgcgacgagc tgagcgaacg gctcaagatc      120

cagcacgagc tgcgcgcgca ggcgcaggtc gaggaggcgg aggaactctt ccgcgacatg      180

cgcttctacg gcccgcagcg gcgccgcctc tggaacctca tggagaagcc gttctcctcg      240

gtggccgcca aggcc                                                       255


<210>  5807
<211>  1641
<212>  DNA
<213>  Homo Sapiens

<400>  5807
gagccggctg agaactcgga cttctacctg cctggggatt acctcctggg tggcctcttc       60

tccctccatg ccaacatgaa gggcattgtt caccttaact tcctgcaggt gcccatgtgc      120

aaggagtatg aagtgaaggt gataggctac aacctcatgc aggccatgcg ctttgcggtg      180

gaggagatca acaatgacag cagcctgctg cctggtgtgc tgctgggcta tgagatcgtg      240

gatgtgtgct acatctccaa caatgtccag ccggtgctct acttcctggc acacgaggac      300

aacctccttc ccatccaaga ggactacagt aactacattt cccgtgtggt ggctgtcatt      360

ggccctgaca actccgagtc tgtcatgact gtggccaact tcctctccct atttctcctt      420

ccacagatca cctacagcgc catcagcgat gagctgcgag acaaggtgcg cttcccggct      480

ttgctgcgta ccacacccag cgccgaccac cacatcgagg ccatggtgca gctgatgctg      540

cacttccgct ggaactggat cattgtgctg gtgagcagcg acacctatgg ccgcgacaat      600

ggccagctgc ttggcgagcg cgtggcccgg cgcgacatct gcatcgcctt ccaggagacg      660

ctgcccacac tgcagcccaa ccagaacatg acgtcagagg agcgccagcg cctggtgacc      720

attgtggaca agctgcagca gagcacagcg cgcgtcgtgg tcgtgttctc gcccgacctg      780

accctgtacc acttcttcaa tgaggtgctg cgccagaact tcactggcgc cgtgtggatc      840

gcctccgagt cctgggccat cgacccggtc ctgcacaacc tcacggagct gcgccacttg      900

ggcaccttcc tgggcatcac catccagagc gtgcccatcc cgggcttcag tgagttccgc      960

gagtggggcc cacaggctgg gccgccaccc ctcagcagga ccagccagag ctatacctgc     1020

aaccaggagt gcgacaactg cctgaacgcc accttgtcct tcaacaccat tctcaggctc     1080

tctggggagc gtgtcgtcta cagcgtgtac tctgcggtct atgctgtggc ccatgccctg     1140

cacagcctcc tcggctgtga caaaagcacc tgcaccaaga gggtggtcta cccctggcag     1200

ctgcttgagg agatctggaa ggtcaacttc actctcctgg accaccaaat cttcttcgac     1260

ccgcaagggg acgtggctct gcacttggag attgtccagt ggcaatggga ccggagccag     1320

aatcccttcc agagcgtcgc ctcctactac cccctgcagc gacagctgaa gaacatccaa     1380

gacatctcct ggcacaccat caacaacacg atccctatgt ccatgtgttc caagaggtgc     1440

cagtcagggc aaaagaagaa gcctgtgggc atccacgtct gctgcttcga gtgcatcgac     1500

tgccttcccg gcaccttcct caaccacact gaagatgaat atgaatgcca ggcctgcccg     1560

aataacgagt ggtcctacca gagtgagacc tcctgcttca agcggcagct ggtcttcctg     1620

gaatggcatg aggcacccac c                                               1641


<210>  5808
<211>  2616
<212>  DNA
<213>  Homo Sapiens

<400>  5808
aacgctatcc ggctcaccag cgagcacacg gtggagaccc tggtggtggc cgacgccgac       60

atggtgcagt accacggggc cgaggccgcc cagaggttca tcctgaccgt catgaacatg      120

gtatacaata tgtttcagca ccagagcctg gggattaaaa ttaacattca agtgaccaag      180

cttgtcctgc tacgacaacg tcccgctaag ttgtccattg ggcaccatgg tgagcggtcc      240

ctggagagct tctgtcactg gcagaacgag gagtatggag gagcgcgata cctcggcaat      300

aaccaggttc ccggcgggaa ggacgacccg cccctggtgg atgctgccgt gtttgtgacc      360

aggacagatt tctgtgtaca caaggatgaa ccgtgtgaca ctgttggaat tgcttactta      420

ggaggtgtgt gcagtgctaa gaggaagtgt gtgcttgccg aagacaatgg tctcaatttg      480

gcctttacca tcgcccatga gctgggccac aacttgggca tgaaccacga cgatgaccac      540

tcatcttgcg ctggcaggtc ccacatcatg tcaggagagt gggtgaaagg ccggaaccca      600

agtgacctct cttggtcctc ctgcagccga gatgaccttg aaaacttcct caagtcaaaa      660

gtcagcacct gcttgctagt cacggacccc agaagccagc acacagtacg cctcccgcac      720

aagctgccgg gcatgcacta cagtgccaac gagcagtgcc agatcctgtt tggcatgaat      780

gccaccttct gcagaaacat ggagcatcta atgtgtgctg gactgtggtg cctggtagaa      840

ggagacacat cctgcaagac caagctggac cctcccctgg atggcaccga gtgtggggca      900

gacaagtggt gccgcgcggg ggagtgcgtg agcaagacgc ccatcccgga gcatgtggac      960

ggagactgga gcccgtgggg cgcctggagc atgtgcagcc gaacatgtgg gacgggagcc     1020

cgcttcaggc agaggaaatg tgacaacccc ccccctgggc ctggaggcac acactgcccg     1080

ggtgccagtg tagaacatgc ggtctgcgag aacctgccct gccccaaggg tctgcccagc     1140

ttccgggacc agcagtgcca ggcacacgac cggctgagcc ccaagaagaa aggcctgctg     1200

acagccgtgg tggttgacga taagccatgt gaactctact gctcgcccct cgggaaggag     1260

tccccactgc tggtggccga cagggtcctg gacggtacac cctgcgggcc ctacgagact     1320

gatctctgcg tgcacggcaa gtgccagaaa atcggctgtg acggcatcat cgggtctgca     1380

gccaaagagg acagatgcgg ggtctgcagc ggggacggca agacctgcca cttggtgaag     1440

ggcgacttca gccacgcccg ggggacagct ctcaaagact cgggtaaggg gtccatcaac     1500

agtgactgga agatagagct ccccggagag ttccagattg caggcacaac tgttcgctat     1560

gtgagaaggg ggctgtggga gaagatctct gccaagggac caaccaaact accgctgcac     1620

ttgatggtgt tgttatttca cgaccaagat tatggaattc attatgaata cactgttcct     1680

gtaaaccgca ctgcggaaaa tcaaagcgaa ccagaaaaac cgcaggactc tttgttcatc     1740

tggacccaca gcggctggga agggtgcagt gtgcagtgcg gcggagggga gcgcagaacc     1800

atcgtctcgt gtacacggat tgtcaacaag accacaactc tggtgaacga cagtgactgc     1860

cctcaagcaa gccgcccaga gccccaggtc cgaaggtgca acttgcaccc ctgccagtca     1920

cggtgggtgg caggcccgtg gagcccctgc tcggcgacct gtgagaaagg cttccagcac     1980

cgggaggtga cctgcgtgta ccagctgcag aacggcacac acgtcgctac gcggcccctc     2040

tactgcccgg gcccccggcc ggcggcagtg cagagctgtg aaggccagga ctgcctgtcc     2100

atctgggagg cgtctgagtg gtcacagtgc tctgccagct gtggtaaagg ggtgtggaaa     2160

cggaccgtgg cgtgcaccaa ctcacaaggg aaatgcgacg catccacgag gccgagagcc     2220

gaggaggcct gcgaggacta ctcaggctgc tacgagtgga aaactgggga ctggtctacg     2280

tgctcgtcga cctgcgggaa gggcctgcag tcccgggtgg tgcagtgcat gcacaaggtc     2340

acagggcgcc acggcagcga gtgccccgcc ctctcgaagc ctgcccccta cagacagtgc     2400

taccaggagg tctgcaacga caggatcaac gccaacacca tcacctcccc ccgccttgct     2460

gctctgacct acaaatgcac acgagaccag tggacggtat attgccgggt catccgagaa     2520

aagaacctct gccaggacat gcggtggtac cagcgctgct gccagacctg cagggacttc     2580

tatgcaaaca agatgcgcca gccaccgccg aactcg                               2616


<210>  5809
<211>  2835
<212>  DNA
<213>  Homo Sapiens

<400>  5809
tctcttctga ggtcccatag aaatgaagaa ctgaacgtgg agaccttggt ggtggtcgac       60

aaaaagatga tgcaaaacca tggccatgaa aatatcacca cctacgtgct cacgatactc      120

aacatggtat ctgctttatt caaagatgga acaataggag gaaacatcaa cattgcaatt      180

gtaggtctga ttcttctaga agatgaacag ccaggactgg tgataagtca ccacgcagac      240

cacaccttaa gtagcttctg ccagtggcag tctggattga tggggaaaga tgggactcgt      300

catgaccacg ccatcttact gactggtctg gatatatgtt cctggaagaa tgagccctgt      360

gacactttgg gatttgcacc cataagtgga atgtgtagta aatatcgcag ctgcacgatt      420

aatgaagata caggtcttgg actggccttc accattgccc atgagtctgg acacaacttt      480

ggcatgattc atgatggaga agggaacatg tgcaaaaagt ccgagggcaa catcatgtcc      540

cctacattgg caggacgcaa tggagtcttc tcctggtcac cctgcagccg ccagtatcta      600

cacaaatttc taagcaccgc tcaagctatc tgccttgctg atcagccaaa gcctgtgaag      660

gaatacaagt atcctgagaa attgccagga gaattatatg atgcaaacac acagtgcaag      720

tggcagttcg gagagaaagc caagctctgc atgctggact ttaaaaagga catctgtaaa      780

gccctgtggt gccatcgtat tggaaggaaa tgtgagacta aatttatgcc agcagcagaa      840

ggcacaattt gtgggcatga catgtggtgc cggggaggac agtgtgtgaa atatggtgat      900

gaaggcccca agcccaccca tggccactgg tcggactggt cttcttggtc cccatgctcc      960

aggacctgcg gagggggagt atctcatagg agtcgcctct gcaccaaccc caagccatcg     1020

catggaggga agttctgtga gggctccact cgcactctga agctctgcaa cagtcagaaa     1080

tgtccccggg acagtgttga cttccgtgct gctcagtgtg ccgagcacaa cagcagacga     1140

ttcagagggc ggcactacaa gtggaagcct tacactcaag tagaagatca ggacttatgc     1200

aaactctact gtatcgcaga aggatttgat ttcttctttt ctttgtcaaa taaagtcaaa     1260

gatgggactc catgctcgga ggatagccgt aatgtttgta tagatgggat atgtgagaga     1320

gttggatgtg acaatgtcct tggatctgat gctgttgaag acgtctgtgg ggtgtgtaac     1380

gggaataact cagcctgcac gattcacagg ggtctctaca ccaagcacca ccacaccaac     1440

cagtattatc acatggtcac cattccttct ggagcccgga gtatccgcat ctatgaaatg     1500

aacgtctcta cctcctacat ttctgtgcgc aatgccctca gaaggtacta cctgaatggg     1560

cactggaccg tggactggcc cggccggtac aaattttcgg gcactacttt cgactacaga     1620

cggtcctata atgagcccga gaacttaatc gctactggac caaccaacga gacactgatt     1680

gtggagctgc tgtttcaggg aaggaacccg ggtgttgcct gggaatactc catgcctcgc     1740

ttggggaccg agaagcagcc ccctgcccag cccagctaca cttgggccat cgtgcgctct     1800

gagtgctccg tgtcctgcgg agggggacag atgaccgtga gagagggctg ctacagagac     1860

ctgaagtttc aagtaaatat gtccttctgc aatcccaaga cacgacctgt cacggggctg     1920

gtgccttgca aagtatctgc ctgtcctccc agctggtccg tggggaactg gagtgcctgc     1980

agtcggacgt gtggcggggg tgcccagagc cgccccgtgc agtgcacacg gcgggtgcac     2040

tatgactcgg agccagtccc ggccagcctg tgccctcagc ctgctccctc cagcaggcag     2100

gcctgcaact ctcagagctg cccacctgca tggagcgccg ggccctgggc agagtgctca     2160

cacacctgtg ggaaggggtg gaggaagcgg gcagtggcct gtaagagcac caacccctcg     2220

gccagagcgc agctgctgcc cgacgctgtc tgcacctccg agcccaagcc caggatgcat     2280

gaagcctgtc tgcttcagcg ctgccacaag cccaagaagc tgcagtggct ggtgtccgcc     2340

tggtcccagt gctctgtgac atgtgaaaga ggaacacaga aaagattctt aaaatgtgct     2400

gaaaagtatg tttctggaaa gtatcgagag ctggcctcaa agaagtgctc acatttgccg     2460

aagcccagcc tggagctgga acgtgcctgc gccccgcttc catgccccag gcacccccca     2520

tttgctgctg cgggaccctc gaggggcagc tggtttgcct caccctggtc tcagtgcacg     2580

gccagctgtg ggggaggcgt tcagacgagg tccgtgcagt gcctggctgg gggccggccg     2640

gcctcaggct gcctcctgca ccagaagcct tcggcctccc tggcctgcaa cactcacttc     2700

tgccccattg cagagaagaa agatgccttc tgcaaagact acttccactg gtgctacctg     2760

gtaccccagc acgggatgtg cagccacaag ttctacggca agcagtgctg caagacttgc     2820

tctaagtcca acttg                                                      2835


<210>  5810
<211>  2214
<212>  DNA
<213>  Homo Sapiens

<400>  5810
ttcgtgtcta tcccgcggta cgtggagacg ctggtggtcg cggacgagtc aatggtcaag       60

ttccacggcg cggacctgga acattatctg ctgacgctgc tggcaacggc ggcgcgactc      120

taccgccatc ccagcatcct caaccccatc aacatcgttg tggtcaaggt gctgcttctt      180

agagatcgtg actccgggcc caaggtcacc ggcaatgcgg ccctgacgct gcgcaacttc      240

tgtgcctggc agaagaagct gaacaaagtg agtgacaagc accccgagta ctgggacact      300

gccatcctct tcaccaggca ggacctgtgt ggagccacca cctgtgacac cctgggcatg      360

gctgatgtgg gtaccatgtg tgaccccaag agaagctgct ctgtcattga ggacgatggg      420

cttccatcag ccttcaccac tgcccacgag ctgggccacg tgttcaacat gccccatgac      480

aatgtgaaag tctgtgagga ggtgtttggg aagctccgag ccaaccacat gatgtccccg      540

accctcatcc agatcgaccg tgccaacccc tggtcagcct gcagtgctgc catcatcacc      600

gacttcctgg acagcgggca cggtgactgc ctcctggacc aacccagcaa gcccatctcc      660

ctgcccgagg atctgccggg cgccagctac accctgagcc agcagtgcga gctggctttt      720

ggcgtgggct ccaagccctg tccttacatg cagtactgca ccaagctgtg gtgcaccggg      780

aaggccaagg gacagatggt gtgccagacc cgccacttcc cctgggccga tggcaccagc      840

tgtggcgagg gcaagctctg cctcaaaggg gcctgcgtgg agagacacaa cctcaacaag      900

cacagggtgg atggttcctg ggccaaatgg gatccctatg gcccctgctc gcgcacatgt      960

ggtgggggcg tgcagctggc caggaggcag tgcaccaacc ccacccctgc caacgggggc     1020

aagtactgcg agggagtgag ggtgaaatac cgatcctgca atctggagcc ctgccccagc     1080

tcagcctccg gaaagagctt ccgggaggag cagtgtgagg ctttcaacgg ctacaaccac     1140

agcaccaacc ggctcactct cgccgtggca tgggtgccca agtactccgg cgtgtctccc     1200

cgggacaagt gcaagctcat ctgccgagcc aatggcactg gctacttcta tgtgctggca     1260

cccaaggtgg tggacggcac gctgtgctct cctgactcca cctccgtctg tgtccaaggc     1320

aagtgcatca aggctggctg tgatgggaac ctgggctcca agaagagatt cgacaagtgt     1380

ggggtgtgtg ggggagacaa taagagctgc aagaaggtga ctggactctt caccaagccc     1440

atgcatggct acaatttcgt ggtggccatc cccgcaggcg cctcaagcat cgacatccgc     1500

cagcgcggtt acaaagggct gatcggggat gacaactacc tggctctgaa gaacagccaa     1560

ggcaagtacc tgctcaacgg gcatttcgtg gtgtcggcgg tggagcggga cctggtggtg     1620

aagggcagtc tgctgcggta cagcggcacg ggcacagcgg tggagagcct gcaggcttcc     1680

cggcccatcc tggagccgct gaccgtggag gtcctctccg tggggaagat gacaccgccc     1740

cgggtccgct actccttcta tctgcccaaa gagcctcggg aggacaagtc ctctcatccc     1800

aaggaccccc ggggaccctc tgtcttgcac aacagcgtcc tcagcctctc caaccaggtg     1860

gagcagccgg acgacaggcc ccctgcacgc tgggtggctg gcagctgggg gccgtgctcc     1920

gcgagctgcg gcagtggcct gcagaagcgg gcggtggact gccggggctc cgccgggcag     1980

cgcacggtcc ctgcctgtga tgcagcccat cggcccgtgg agacacaagc ctgcggggag     2040

ccctgcccca cctgggagct cagcgcctgg tcaccctgct ccaagagctg cggccgggga     2100

tttcagaggc gctcactcaa gtgtgtgggc cacggaggcc ggctgctggc ccgggaccag     2160

tgcaacttgc accgcaagcc ccaggagctg gacttctgcg tcctgaggcc gtgc           2214


<210>  5811
<211>  2811
<212>  DNA
<213>  Homo Sapiens

<400>  5811
tcagctggaa aatcacaaaa gggcctcaat gtggaaaccc tcgtggtggc agacaagaaa       60

atggtggaaa agcatggcaa gggaaatgtc accacataca ttctcacagt aatgaacatg      120

gtttctggcc tatttaaaga tgggactatt ggaagtgaca taaacgtggt tgtggtgagc      180

ctaattcttc tggaacaaga acctggagga ttattgatca accatcatgc agaccagtct      240

ctgaatagtt tttgtcaatg gcagtctgcc ctcattggaa agaatggcaa gagacatgat      300

catgccatct tactaacagg atttgatatt tgttcttgga agaatgaacc atgtgacact      360

ctagggtttg cccccatcag tggaatgtgc tctaagtacc gaagttgtac catcaatgag      420

gacacaggac ttggccttgc cttcaccatc gctcatgagt cagggcacaa ctttggtatg      480

attcacgacg gagaagggaa tccctgcaga aaggctgaag gcaatatcat gtctcccaca      540

ctgaccggaa acaatggagt gttttcatgg tcttcctgca gccgccagta tctcaagaaa      600

ttcctcagca cacctcaggc ggggtgtcta gtggatgagc ccaagcaagc aggacagtat      660

aaatatccgg acaaactacc aggacagatt tatgatgctg acacacagtg taaatggcaa      720

tttggagcaa aagccaagtt atgcagcctt ggttttgtga aggatatttg caaatcactt      780

tggtgccacc gagtaggcca caggtgtgag accaagttta tgcccgcagc agaagggacc      840

gtttgtggct tgagtatgtg gtgtcggcaa ggccagtgcg taaagtttgg ggagctcggg      900

ccccggccca tccacggcca gtggtccgcc tggtcgaagt ggtcagaatg ttcccggaca      960

tgtggtggag gagtcaagtt ccaggagaga cactgcaata accccaagcc tcagtatggt     1020

ggcatattct gtccaggttc tagccgtatt tatcagctgt gcaatattaa cccttgcaat     1080

gaaaatagct tggattttcg ggctcaacag tgtgcagaat ataacagcaa acctttccgt     1140

ggatggttct accagtggaa accctataca aaagtggaag aggaagatcg atgcaaactg     1200

tactgcaagg ctgagaactt tgaatttttt tttgcaatgt ccggcaaagt gaaagatgga     1260

actccctgct ccccaaacaa aaatgatgtt tgtattgacg gggtttgtga actagtggga     1320

tgtgatcatg aactaggctc taaagcagtt tcagatgctt gtggcgtttg caaaggtgat     1380

aattcaactt gcaagtttta taaaggcctg tacctcaacc agcataaagc aaatgaatat     1440

tatccggtgg tcatcattcc agctggcgcc cgaagcatcg aaatccagga gctgcaggtt     1500

tcctccagtt acctcgcagt tcgaagcctc agtcaaaagt attacctcac cgggggctgg     1560

agcatcgact ggcctgggga gttccccttc gctgggacca cgtttgaata ccagcgctct     1620

ttcaaccgcc cggaacgtct gtacgcgcca gggcccacaa atgagacgct ggtctttgaa     1680

attctgatgc aaggcaaaaa tccagggata gcttggaagt atgcacttcc caaggtcatg     1740

aatggaactc caccagccac aaaaagacct gcctatacct ggagtatcgt gcagtcagag     1800

tgctccgtct cctgtggtgg aggttacata aatgtaaagg ccatttgctt gcgagatcaa     1860

aatactcaag tcaattcctc attctgcagt gcaaaaacca agccagtaac tgagcccaaa     1920

atctgcaacg ctttctcctg cccggcttac tggatgccag gtgaatggag tacatgcagc     1980

aaggcctgtg ctggaggcca gcagagccga aagatccagt gtgtgcaaaa gaagcccttc     2040

caaaaggagg aagcagtgtt gcattctctc tgtccagtga gcacacccac tcaggtccaa     2100

gcctgcaaca gccatgcctg ccctccacaa tggagccttg gaccctggtc tcagtgttcc     2160

aagacctgtg gacgaggggt gaggaagcgt gaactcctct gcaagggctc tgccgcagaa     2220

accctccccg agagccagtg taccagtctc cccagacctg agctgcagga gggctgtgtg     2280

cttggacgat gccccaagaa cagccggcta cagtgggtcg cttcttcgtg gagcgagtgt     2340

tctgcaacct gtggtttggg tgtgaggaag agggagatga agtgcagcga gaagggcttc     2400

cagggaaagc tgataacttt cccagagcga agatgccgta atattaagaa accaaatctg     2460

gacttggaag agacctgcaa ccgacgggct tgcccagccc atccagtgta caacatggta     2520

gctggatggt attcattgcc gtggcagcag tgcacagtca cctgtggggg aggggtccag     2580

acccggtcag tccactgtgt tcagcaaggc cggccttcct caagttgtct gctccatcag     2640

aaacctccgg tgctacgagc ctgtaataca aacttctgtc cagctcctga aaagagagag     2700

gatccatcct gcgtagattt cttcaactgg tgtcacctag ttcctcagca tggtgtctgc     2760

aaccacaagt tttacggaaa acaatgctgc aagtcatgca caaggaagat c              2811


<210>  5812
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  5812
gctgaagcag tgtggaccgc gtacctcaac gtgtcctggc gggttccgca cacgggagtg       60

aaccgtacgg tgtgggagct gagcgaggag ggcgtgtacg gccaggactc gccgctggag      120

cctgtggctg gggtcctggt accgcccgac gggcccgggg cgcttaacgc ctgtaacccg      180

cacacgaatt tcacggtgcc cacggtttgg ggaagcaccg tgcaagtctc ttggttggcc      240

ctcatccaac gcggcggggg ctgcaccttc gcagacaaga tccatctggc ttatgagaga      300

ggggcgtctg gagccgtcat ctttaacttc cccgggaccc gcaatgaggt catccccatg      360

tctcacccgg gtgcagtaga cattgttgca atcatgatcg gcaatctgaa aggcacaaaa      420

attctgcaat ctattcaaag aggcatacaa gtgacaatgg tcatagaagt agggaaaaaa      480

catggccctt gggtgaatca ctattca                                          507


<210>  5813
<211>  192
<212>  DNA
<213>  Homo Sapiens

<400>  5813
ttgaaccctc agaagccact gtatagctcc tgccttagtg tggagaagtg ttaccagcaa       60

aaagactggc agcgtttact gctctctccc cttcaccatg ctgatgattg gcatttgtat      120

ttcaatatgg catccatgct ctggaaagga ataaatctag aaagaagact gggaagtaga      180

tggtttgcct at                                                          192


<210>  5814
<211>  849
<212>  DNA
<213>  Homo Sapiens

<400>  5814
tcctctccct gcatcatgga gaagaaagac ctcggcccca agcctgctct cattggccac       60

cgcggggccc ccatgctggc tccagagcac acgctcatgt ccttccggaa ggccctcgag      120

cagaagctgt acgggctcca ggctgacatt accatcagcc tggacggcgt gcccttcctc      180

atgcatgaca ccaccctgcg gcgcaccacc aacgtggagg aggagttccc ggagctggcc      240

cgcaggcctg cctccatgct taactggacc accctgcaga gactcaacgc tggccagtgg      300

ttcctgaaga ctgtcccctt ctggacagcc agctccctgt caccctccga ccacagagag      360

gcccagaacc agtccatctg cagcctggca gagctcctgg agctggccaa gggcaatgcc      420

acactgctgc tcaacctgcg tgacccgccc cgggagcacc cctaccgcag cagttttatc      480

aacgtgactc tggaggccgt gctgcactcc ggcttccccc agcaccaggt catgtggctg      540

cctagcaggc agaggcccct ggtgcggaag gtggctcccg gcttccaaca gacatcaggc      600

tccaaggagg cagtcgccag cctgcggaga ggccacatcc agcggctgaa cctgcgctac      660

actcaggtgt cccgccagga gctcagggac tacgcgtcct ggaacctgag tgtgaacctc      720

tacacagtca acgcaccgtg gctcttctcc ctgctgtggt gtgcgggggt cccatccgtc      780

acctctgaca actcccacac cctgtcccag gtgccttccc ccctctggat catgcccccg      840

gacgagtac                                                              849


<210>  5815
<211>  1233
<212>  DNA
<213>  Homo Sapiens

<400>  5815
ccgtcgctca tcaagcagca ggtccttaag aacgtgcgca tcgaccccag tagcctgtcc       60

ttcaacatgt ggaaggagat ccctatcccc ttctatctct ccgtctactt ctttgacgtc      120

atgaacccca gcgagatcct gaagggcgag aagccgcagg tgcgggagcg cgggccctac      180

gtgtacaggg agttcaggca caaaagcaac atcaccttca acaacaacga caccgtgtcc      240

ttcctcgagt accgcacctt ccagttccag ccctccaagt cccacggctc ggagagcgac      300

tacatcgtca tgcccaacat cctggtcttg ggtgcggcgg tgatgatgga gaataagccc      360

atgaccctga agctcatcat gaccttggca ttcaccaccc tcggcgaacg tgccttcatg      420

aaccgcactg tgggtgagat catgtggggc tacaaggacc cccttgtgaa tctcatcaac      480

aagtactttc caggcatgtt ccccttcaag gacaagttcg gattatttgc tgagctcaac      540

aactccgact ctgggctctt cacggtgttc acgggggtcc agaacatcag caggatccac      600

ctcgtggaca agtggaacgg gctgagcaag gttgacttct ggcattccga tcagtgcaac      660

atgatcaatg gaacttctgg gcaaatgtgg ccgcccttca tgactcctga gtcctcgctg      720

gagttctaca gcccggaggc ctgccgatcc atgaagctaa tgtacaagga gtcaggggtg      780

tttgaaggca tccccaccta tcgcttcgtg gctcccaaaa ccctgtttgc caacgggtcc      840

atctacccac ccaacgaagg cttctgcccg tgcctggagt ctggaattca gaacgtcagc      900

acctgcaggt tcagtgcccc cttgtttctc tcccatcctc acttcctcaa cgctgacccg      960

gttctggcag aagcggtgac tggcctgcac cctaaccagg aggcacactc cttgttcctg     1020

gacatccacc cggtcacggg aatccccatg aactgctctg tgaaactgca gctgagcctc     1080

tacatgaaat ctgtcgcagg cattggacaa actgggaaga ttgagcctgt ggtcctgccg     1140

ctgctctggt ttgcagagag cggggccatg gagggggaga ctcttcacac attctacact     1200

cagctggtgt tgatgcccaa ggtgatgcac tat                                  1233


<210>  5816
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  5816
gacagggcgc cactcacagc cacagcccca caactggatg atgaggagat gtactcagcc       60

cacatgcccg ctcacctgcg ctgtgatgcc tgcagagctg tggcttacca gatgtggcaa      120

aatctggcaa aggcagagac caaacttcat acctcaaact ctggggggcg gcgggagctg      180

agcgagttgg tctacacgga tgtcctggac cggagctgct cccggaactg gcaggactac      240

ggagttcgag aagtggacca agtgaaacgt ctcacaggcc caggacttag cgaggggcca      300

gagccaagca tcagcgtgat ggtcacaggg ggcccctggc ctaccaggct ctccaggaca      360

tgtttgcact acttggggga gtttggagaa gaccagatct atgaagccca ccaacaaggc      420

cgaggggctc tggaggcatt gctatgtggg ggaccccagg gggcctgctc agagaaggtg      480

tcagccacaa gagaagagct c                                                501


<210>  5817
<211>  1194
<212>  DNA
<213>  Homo Sapiens

<400>  5817
caaatccagc agggaggtcc agatgaaaaa gaaaagacta ccgcactgaa agatttatta       60

tctaggatag atttggatga actaatgaaa aaagatgaac cgcctcttga ttttcctgat      120

accctgggag gatttgaata tgcttttaat gaaaagggac agttaagaca cataaaaact      180

ggggaaccat ttgtttttaa ctaccgggaa gatttacaca gatggaacca gaaaagatac      240

gaggctctag gagagatcat cacgaagtat gtatatgagc tcctggaaaa ggattgtaat      300

ttgaaaaaag tatctattcc agtagatgcc actgagagtg aaccaaagag ttttatcttt      360

atgagtgagg atgctttgac aaatccacag aaactgatgg ttttaattca tggtagtggt      420

gttgtcaggg cagggcagtg ggctagaaga cttattataa atgaagatct ggacagtggc      480

acacagatac cgtttattaa aagagctgtg gctgaaggat atggagtaat agtactaaat      540

cccaatgaaa actatattga agtagaaaag ccgaagatac acgtacagtc atcatctgat      600

agttcagatg aaccagcaga aaaacgggaa agaaaagata aagtttctaa agaaacaaag      660

aagcgacgtg atttctatga gaagtatcgt aacccccaaa gagaaaaaga aatgatgcaa      720

ttgtatatca gagaaaatgg ttctcctgaa gaacatgcaa tctatgtttg ggatcatttc      780

atagctcagg ctgctgctga gaatgtgttt ttcgttgctc acagctatgg aggacttgct      840

tttgttgaac tgatgattca acgagaagcc gatgtaaaaa ataaggtaac tgctgtggca      900

ttgacagact ctgttcacaa tgtgtggcat caagaagctg gcaaaacgat tcgagaatgg      960

atgagagaga actgttgtaa ttgggtctct agctcagaac cattagacac atcagtggag     1020

tccatgctac ctgattgccc ccgggtctca gcaggcaccg accgtcacga gctaacttcc     1080

tggaagagct ttccgtctat tttcaaattc tttaccgaag cctcagaggc caagaccagc     1140

tccctgaagc cggctgtgac gcgccgctcc caccgcatca agcacgaaga tctg           1194


<210>  5818
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  5818
gcacggctta tgggctggtg gggtccccgc gctggctttc gccttttcat accggaggag       60

ctgtctcgct accgcggcgg cccaggggac ccgggcctgt acttggcgtt gctcggccgt      120

gtctacgatg tgtcctccgg ccggaggcac tacgagcctg ggtcccacta tagcggcttc      180

gcaggccgag acgcatccag agctttcgtg accggggact gttctgaagc aggcctcgtg      240

gatgacgtat ccgacctgtc agccgctgag atgctgacac ttcacaattg gctttcattc      300

tatgagaaga attatgtgtg tgttgggagg gtgacaggac ggttctacgg agaggatggg      360

ctgcccaccc cggcactgac ccaggtagaa gctgcgatca ccagaggctt ggaggccaac      420

aaactacagc tgcaagagaa gcagacattc ccgccgtgca acgcggagtg gagctcagcc      480

aggggcagcc ggctctggtg ctcccagaag agtggaggtg tgagcagaga ctggattggc      540

gtccccagga agctgtataa gccaggtgct aaggagcccc gctgcgtgtg tgtgagaacc      600

accggccccc ctagtggcca gatgccggac aaccctccac acagaaatcg tggggacctg      660

gaccacccaa acttggcaga gtacacaggc tgcccaccgc tagccatcac atgctccttt      720

ccactc                                                                 726


<210>  5819
<211>  2616
<212>  DNA
<213>  Homo Sapiens

<400>  5819
gcgacattca tctcgatgca gctgaaaaag acctcagagg tggacctggc caagccgctg       60

gtgaagttca tccagcagac ttacccaagc ggcggggaag agcaggccca gtactgccgc      120

gcggcggagg agctcagcaa gctgcgccgc gccgcagtcg gtcgtccgct ggacaagcac      180

gagggcgcgc tcgagacgct cctgagatat tatgatcaga tttgttctat tgaacccaaa      240

ttcccatttt ctgaaaatca gatctgcttg acatttacct ggaaggatgc tttcgataaa      300

ggttcacttt ttggaggctc tgtaaaactg gctcttgcaa gcttaggata tgaaaagagc      360

tgtgtgttgt tcaattgtgc agccttagct agccaaattg cagcagaaca gaacctggat      420

aatgatgaag gattgaaaat cgctgctaaa cattaccagt ttgctagtgg tgccttttta      480

catattaaag agacggtttt atctgcctta agtcgagagc cgaccgtgga catatctcca      540

gatactgttg ggaccctcag tcttattatg ctggcacagg ctcaagaagt atttttttta      600

aaagccacaa gagataaaat gaaagatgcc atcatagcta aattggctaa tcaggctgca      660

gattattttg gtgatgcttt caaacagtgt caatacaaag atactctccc caagtatttt      720

tatttccagg aggtgttccc tgtcttggct gcaaagcact gtatcatgca ggccaatgct      780

gagtaccatc agtctatcct ggcaaaacag cagaagaaat ttggagaaga aattgcaagg      840

ttacagcatg cagcagaact gattaaaaca gtggcatctc gctatgatga atatgttaat      900

gtgaaggatt tttctgacaa aatcaatcgt gcccttgctg cagcaaagaa ggataatgac      960

ttcatttatc atgatcgagt tccagacctt aaagatctag atcctattgg caaagccaca     1020

cttgtgaaat ctaccccggt caatgtaccc atcagtcaga aatttactga tctgtttgag     1080

aagatggttc ccgtgtcagt acagcagtct ttggctgcct ataatcagag gaaagccgat     1140

ttgattaaca gatcaattgc tcagatgaga gaagccacca ctttggcaaa tggggtgcta     1200

gcttccctta atcttccagc agcaattgaa gatgtgtctg gagacactgt acctcagtct     1260

atattgacta aatccagatc tgtgattgaa cagggaggca tccagactgt tgatcagttg     1320

attaaagaac tgcctgaatt actgcaacga aatagagaaa tcctagatga gtcattaagg     1380

ttgttggatg aagaagaagc aaccgataat gatttaagag caaaatttaa ggaacgttgg     1440

caaaggacac catccaatga actgtataag cctttaagag cagagggaac caacttcaga     1500

acagttttag ataaagctgt gcaggcagat ggacaagtga aagaatgcta ccagtctcat     1560

cgtgacacca tcgtgctttt gtgtaagcca gagcctgagc tgaatgctgc catcccttct     1620

gctaatccag caaagaccat gcagggcagt gaggttgtaa atgtcttaaa atccttattg     1680

tcaaatcttg atgaagtaaa gaaggaaaga gagggtctgg agaatgactt gaaatctgtg     1740

aattttgaca tgacaagcaa gtttttgaca gccctggctc aagatggtgt gataaatgaa     1800

gaagctcttt ctgttactga actagatcga gtctatggag gtcttacaac taaagtccaa     1860

gaatctctaa agaaacagga gggacttctt aaaaatattc aggtctcaca tcaggaattt     1920

tcaaaaatga aacaatctaa taatgaagct aacttaagag aagaagtttt gaagaattta     1980

gctactgcat atgacaactt tgttgaactt gtagctaatt tgaaggaagg cacaaagttt     2040

tacaatgagt tgactgaaat cctggtcagg ttccagaaca aatgcagtga tatagttttt     2100

gcacggaaga cagaaagaga tgaactctta aaggacttgc aacaaagcat tgccagagaa     2160

cctagtgctc cttcaattcc tacacctgcg tatcagtcct caccagcagg aggacatgca     2220

ccaactcctc caactccagc gccaagaacc atgccgccta ctaagcccca gcccccagcc     2280

aggcctccac cacctgtgct tccagcaaat cgagctcctt ctgctactgc tccatctcca     2340

gtgggggctg ggactgctgc gccagctcca tcacaaacgc ctggctcagc tcctcctcca     2400

caggcgcagg gaccacccta tcccacctat ccaggatatc ctgggtattg ccaaatgccc     2460

atgcccatgg gctataatcc ttatgcgtat ggccagtata atatgccata tccaccagtg     2520

tatcaccaga gtcctggaca ggctccatac ccgggacccc agcagccttc ataccccttc     2580

cctcagcccc cacagcagtc ttactatcca cagcag                               2616


<210>  5820
<211>  780
<212>  DNA
<213>  Homo Sapiens

<400>  5820
tgtcccagga tgaagagaaa aattgaacga gaaataaagt gtagtccttc tgaaagcccc       60

ttaatggaaa aaaagaatag cttgaaagaa gaccatgaag aaacaaagtt gtctgttggt      120

gatattgaaa acaagcatcc tgtttctgag gtagggcctg ccactgtgcc cctccaggct      180

gtggtggagg agagaacagt ctcattcaaa cttggagatt tggaggaagc tccagagaga      240

gagaggcttc ccagcgtgga cttgaaagag gaaaccagca tagatagcac cgtgaatggt      300

gcagtgcagt tgcctaatgg gaaccttgtc cagttcagtc aagccgtcag caaccaaata      360

aactccagtg gccactacca gtatcacacc gtgcataagg attccggcct gtacaaagag      420

ctactccata aattacatct tgccaaggtg ggagattgca tgggagactc cggtgacaaa      480

cccttaaggc gcaataatag ctatacttcc tataccatgg caatatgtgg catgcctctg      540

gattcattcc gtgccaaaga aggtgaacag aagggcgaag aaatggagaa gctgacatgg      600

cctaatgcag actccaagaa gcgaattcga atggacagtt acaccagtta ctgcaatgct      660

gtgtctgacc ttcactcagc atctgagata gacatgagtg tcaaggcaga gatgggtcta      720

ggtgacagaa aaggaagtaa tggctctcta gaagaatggt atgaccagga taagcctgaa      780


<210>  5821
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  5821
acagatgagg ctaatactta cttcaaggaa tggacctgtt cttcgtctcc atctctgccc       60

agaagctgca aggaaatcaa agacgaatgt cctagtgcat ttgatggcct gtattttctc      120

cgcactgaga atggtgttat ctaccagacc ttctgtgaca tgacctctgg gggtggcggc      180

tggaccctgg tggccagcgt gcacgagaat gacatgcgtg ggaagtgcac ggtgggcgat      240

cgctggtcca gtcagcaggg cagcaaagca gtctacccag agggggacgg caactgggcc      300

aactacaaca cctttggatc tgcagaggcg gccacgagcg atgactacaa gaaccctggc      360

tactacgaca tccaggccaa ggacctgggc atctggcacg tgcccaataa gtcccccatg      420

cagcactgga gaaacagctc cctgctgagg taccgcacgg acactggctt cctccagaca      480

ctgggacata atctgtttgg catctaccag aaatatccag tgaaatatgg agaaggaaag      540

tgttggactg acaacggccc ggtgatccct gtggtctatg attttggcga cgcccagaaa      600

acagcatctt attactcacc ctatggccag cgggaattca ctgcgggatt tgttcagttc      660

agggtattta ataacgagag agcagccaac gccttgtgtg ctggaatgag ggtcaccgga      720

tgtaacactg agcaccactg cattggtgga ggaggatact ttccagaggc cagtccccag      780

cagtgtggag atttttctgg ttttgattgg agtggatatg gaactcatgt tggttacagc      840


<210>  5822
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  5822
caagaatatg aggatgaaga aagactggga gaggatgaat attatcaggt ggtctattat       60

tatacagtca cccccagtta tgatgacttt agtgcagatt tcaccattga ttactccata      120

tttgagtcag aggacaggct gaacaggttg gataaggaca taacagaagc aatagagact      180

accattagtc ttgaaacagc acgtgcagac catccgaagc ctgtaactgt gaaaccagta      240

acaacggaac ctagcccaga tctgaacgat gccgtgtcca gtttgcgaag tcctattccc      300

ctcctcctgt cgtgtgcctt tgttcaggtg gggatgtatt tcatg                      345


<210>  5823
<211>  1653
<212>  DNA
<213>  Homo Sapiens

<400>  5823
ggagacagga gacccttgcc tgtagacaga gctgcaggtt tgaaggaaaa gaccctgatt       60

ctacttgatg tgagcaccaa gaacccagtc aggacagtca atgagaactt cctctctctg      120

cagctggatc cgtccatcat tcatgatggc tggctcgatt tcctaagctc caagcgcttg      180

gtgaccctgg cccggggact ttcgcccgcc tttctgcgct tcgggggcaa aaggaccgac      240

ttcctgcagt tccagaacct gaggaacccg gcgaaaagcc gcgggggccc gggcccggat      300

tactatctca aaaactatga ggatgacatt gttcgaagtg atgttgcctt agataaacag      360

aaaggctgca agattgccca gcaccctgat gttatgctgg agctccaaag ggagaaggca      420

gctcagatgc atctggttct tctaaaggag caattctcca atacttacag taatctcata      480

ttaacagcca ggtctctaga caaactttat aactttgctg attgctctgg actccacctg      540

atatttgctc taaatgcact gcgtcgtaat cccaataact cctggaacag ttctagtgcc      600

ctgagtctgt tgaagtacag cgccagcaaa aagtacaaca tttcttggga actgggtaat      660

gagccaaata actatcggac catgcatggc cgggcagtaa atggcagcca gttgggaaag      720

gattacatcc agctgaagag cctgttgcag cccatccgga tttattccag agccagctta      780

tatggcccta atattgggcg gccgaggaag aatgtcatcg ccctcctaga tggattcatg      840

aaggtggcag gaagtacagt agatgcagtt acctggcaac attgctacat tgatggccgg      900

gtggtcaagg tgatggactt cctgaaaact cgcctgttag acacactctc tgaccagatt      960

aggaaaattc agaaagtggt taatacatac actccaggaa agaagatttg gcttgaaggt     1020

gtggtgacca cctcagctgg aggcacaaac aatctatccg attcctatgc tgcaggattc     1080

ttatggttga acactttagg aatgctggcc aatcagggca ttgatgtcgt gatacggcac     1140

tcattttttg accatggata caatcacctc gtggaccaga attttaaccc attaccagac     1200

tactggctct ctctcctcta caagcgcctg atcggcccca aagtcttggc tgtgcatgtg     1260

gctgggctcc agcggaagcc acggcctggc cgagtgatcc gggacaaact aaggatttat     1320

gctcactgca caaaccacca caaccacaac tacgttcgtg ggtccattac actttttatc     1380

atcaacttgc atcgatcaag aaagaaaatc aagctgactg ggactctcag agacaagctg     1440

gttcaccagt acctgctgca gccctatggg caggagggcc taaagtccaa gtcagtgcaa     1500

ctgaatggcc agcccttagt gatggtggac gacgggaccc tcccagaatt gaagccccgc     1560

ccccttcggg ccggccggac attggtcatc cctccagtca ccatgggctt ttttgtggtc     1620

aagaatgtca atgctttggc ctgccgctac cga                                  1653


<210>  5824
<211>  897
<212>  DNA
<213>  Homo Sapiens

<400>  5824
gcagcagcct cttctcttga gatgctctcg agggaattcg aaacctgtgc cttctccttt       60

tcttccctgc ctagaagctg caaagaaatc aaggaacgct gccatagtgc aggtgatggc      120

ctgtattttc tccgcaccaa gaatggtgtt gtctaccaga ccttctgtga catgacttct      180

gggggtggcg gctggaccct ggtggccagc gtgcacgaga atgacatgca tgggaagtgc      240

acggtgggtg atcgctggtc cagtcagcag ggcaacaaag cagactaccc agagggggat      300

ggcaactggg ccaactacaa cacctttgga tctgcagagg cggccacgag cgatgactac      360

aagaaccctg gctactacga catccaggcc aaggacctgg gcatctggca tgtgcccaac      420

aagtccccca tgcagcattg gagaaacagc gccctgctga ggtaccgcac caacactggc      480

ttcctccaga gactgggaca taatctgttt ggcatctacc agaaataccc agtgaaatac      540

agatcaggga aatgttggaa tgacaatggc ccagccatac ctgtggtcta tgactttggt      600

gatgctaaga agactgcatc ttattactca ccgtatggtc aacgggaatt tgttgcagga      660

ttcgttcagt tccgggtgtt taataacgag agagcagcca acgccctttg tgctgggata      720

aaagttactg gctgtaacac tgagcatcac tgcatcggtg gaggagggtt cttcccacag      780

ggcaaacccc gtcagtgtgg ggacttctcc gcctttgact gggatggata tggaactcac      840

gttaagagca gctgcagtcg ggagataacg gaggcggctg tactcttgtt ctataga         897


<210>  5825
<211>  264
<212>  DNA
<213>  Homo Sapiens

<400>  5825
gttaaagagg gtatagagaa agcaggggtt tgcccagctg acaacgtacg ctgcttcaag       60

tccgatcctc cccagtgtca cacagaccag gactgtctgg gggaaaggaa gtgttgttac      120

ctgcactgtg gcttcaagtg tgtgattcct gtgaaggaac tggaagaagg aggaaacaag      180

gatgaagatg tgtcaaggcc ataccctgag ccaggatggg aggccaagtg tccaggctcc      240

tcctctacca ggtgtcctca gaaa                                             264


<210>  5826
<211>  1299
<212>  DNA
<213>  Homo Sapiens

<400>  5826
gaagaaacat gtccttcatt caccaggctg agctttcaca gtgcagtggt tggtacggga       60

ctaaatgtga ggctgatgct ctacacaagg aaaaacctga cctgcgcaca aaccatcaac      120

tcctcagctt ttgggaactt gaatgtgacc aagaaaacca ccttcattgt ccatggattc      180

aggccaacag gctcccctcc tgtttggatg gatgacttag taaagggttt gctctctgtt      240

gaagacatga acgtagttgt tgttgattgg aatcgaggag ctacaacttt aatatatacc      300

catgcctcta gtaagaccag aaaagtagcc atggtcttga aggaatttat tgaccagatg      360

ttggcagaag gagcttctct tgatgacatt tacatgatcg gagtaagtct aggagcccac      420

atatctgggt ttgttggaga gatgtacgat ggatggctgg ggagaattac aggcctcgac      480

cctgcaggcc ctttattcaa cgggaaacct caccaagaca gattagatcc cagtgatgcg      540

cagtttgttg atgtcatcca ttccgacact gatgcactgg gctacaagga gccattagga      600

aacatagact tctacccaaa tggaggattg gatcaacctg gctgccccaa aacaatattg      660

ggaggatttc agtattttaa atgtgaccac cagaggtctg tatacctgta cctgtcttcc      720

ctgagagaga gctgcaccat cactgcgtat ccctgtgact cctaccagga ttataggaat      780

ggcaagtgtg tcagctgcgg cacgtcacaa aaagagtcct gtccccttct gggctattat      840

gctgataatt ggaaagacca tctaaggggg aaagatcctc caatgacgaa ggcattcttt      900

gacacagctg aggagagccc attctgcatg tatcattact ttgtggatat tataacatgg      960

aacaagaatg taagaagagg ggacattacc atcaaattga gagacaaagc tggaaacacc     1020

acagaatcca aaatcaatca tgaacccacc acatttcaga aatatcacca agtgagtcta     1080

cttgcaagat ttaatcaaga tctggataaa gtggctgcaa tttccttgat gttctctaca     1140

ggatctctaa taggcccaag gtacaagctc aggattctcc gaatgaagtt aaggtccctt     1200

gcccatccgg agaggcctca gctgtgtcgg tatgatcttg tcctgatgga aaacgttgaa     1260

acagtcttcc aacctattct ttgcccagag ttgcagttg                            1299


<210>  5827
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  5827
caggagttcg atccccacac cgttatgcag aggaactaca acgtggccag ggtttcaggg       60

gtctggtatt ctattttcat ggcctcagat gacctgaatc ggattaaaga aaatggagac      120

ctgagggtct tcgtccggaa tattgaacac ttgaagaacg gcagcctaat atttgatttc      180

gaatacatgg tgcaggggga gtgtgtggct gtggtcgtgg tctgcgagaa gacagagaag      240

aatggggaat actccatcaa ctatgagggc cagaacacag tggccgtctc ggagactgac      300

tacaggctgt tcatcacctt ccacctccag aacttcagga acgggaccga gacccacacg      360

ctggcgctct atgaaacctg cgaaaagtac ggacttggct cacaaaatat catcgacttg      420

accaacaaag atccctgcta ctccaagcat tacaggagcc cgcccaggcc tcccatgcgg      480

tgg                                                                    483


<210>  5828
<211>  663
<212>  DNA
<213>  Homo Sapiens

<400>  5828
tttaccatca attgctcagg ctttgaccag catggggttg accctgctgt cttccaagca       60

gtgtttgaca gaaaggcctt ccgtccattc accaactaca gcatccctac ccgtgtcaac      120

atctccttca ccctgtctgc catcctggga gtggatgcac agctccagct gctgacatca      180

ttcctgtgga tggatttggt atgggacaat cctttcatta attggaaccc aaaagagtgt      240

gttggcatca ataaactcac agtattagct gaaaacctgt ggctcccaga catcttcatc      300

gtggaatcca tggatgtgga tcagacgcct tccggtctca ctgcctatat cagcagtgaa      360

ggtcgaatta agtatgataa gccaatgagg gtgaccagca tctgtaacct ggacatcttc      420

tacttccctt ttgaccaaca gaactgtacc ttcaccttca gttctttcct ctacacagtg      480

gacagcatgc tgctgggcat ggacaaggag gtgtgggaga tcacagacac gtctcgcaaa      540

gtcatccaaa cccaggggga gtgggagctc ttgggcatca acaaggccac cccaaagatg      600

tccatgggca acaacctata tgaccagatc atgttttatg tggccatcag gcgcaggcca      660

agc                                                                    663


<210>  5829
<211>  1347
<212>  DNA
<213>  Homo Sapiens

<400>  5829
ttccccaaac ctggaggaag ccaagacaaa tctctacata atagagaatt aagtgcagaa       60

agacctttga atgaacagat tgctgaagca gaagaagaca agattaaaaa aacatatcct      120

ccagaaaaca agccaggtca gagcaactat tcttttgttg ataacttgaa cctgctaaag      180

gcaataacag aaaaggaaaa aattgagaaa gaaagacaat ctataagaag ctccccactt      240

gataataagt tgaatgtgga agatgttgat tcaaccaaga atcgaaaact gatcgatgat      300

tatgactcta ctaagagtgg attggatcat aaatttcaag atgatccaga tggtcttcat      360

caactagacg ggactccttt aaccgctgaa gacattgtcc ataaaatcgc tgccaggatt      420

tatgaagaaa atgacagagc cgcgtttgac aagattgttt ctaaactact taatctcggc      480

cttatcacag aaagccaagc acatacactg gaagatgaag tagcagaggt tttacaaaaa      540

ttaatctcaa aggaagccaa caattatgag gaggatccca ataagcccac aagctggact      600

gagaatcagg ctggaaaaat accagagaaa gtgactccaa tggcagcaat tcaagatggt      660

cttgctaagg gagaaaacga tgaaacagta tctaacacat taaccttgac aaatggcttg      720

gaaaggagaa ctaaaaccta cagtgaagac aactttgagg aactccaata tttcccaaat      780

ttctatgcgc tactgaaaag tattgattca gaaaaagaag caaaagagaa agaaacactg      840

attactatca tgaaaacact gattgacttt gtgaagatga tggtgaaata tggaacaata      900

tctccagaag aaggtgtttc ctaccttgaa aacttggatg aaatgattgc tcttcagacc      960

aaaaacaagc tagaaaaaaa tgctactgac aatataagca agcttttccc agcaccatca     1020

gagaagagtc atgaagaaac agacagtacc aaggaagaag cagctaagat ggaaaaggaa     1080

tatggaagct tgaaggattc cacaaaagat gataactcca acccaggagg aaagacagat     1140

gaacccaaag gaaaaacaga agcctatttg gaagccatca gaaaaaatat tgaatggttg     1200

aagaaacatg acaaaaaggg aaataaagaa gattatgacc tttcaaagat gagagacttc     1260

atcaataaac aagctgatgc ttatgtggag aaaggcatcc ttgacaagga agaagccgag     1320

gccatcaagc gcatttatag cagcctg                                         1347


<210>  5830
<211>  930
<212>  DNA
<213>  Homo Sapiens

<400>  5830
ctggagcgca gcaccaacag cttcagttac tcatcatacc acaccctgga ggagatatat       60

agctggattg acaactttgt aatggagcat tccgatattg tctcaaaaat tcagattggc      120

aacagctttg aaaaccagtc cattcttgtc ctgaagttca gcactggagg ttctcggcac      180

ccagccatct ggatcgacac tggaattcac tcccgggagt ggatcaccca tgccaccggc      240

atctggactg ccaataagat tgtcagtgat tatggcaaag accgtgtcct gacagacata      300

ctgaatgcca tggacatctt catagagctc gtcacaaacc ctgatgggtt tgcttttacc      360

cacagcatga accgcttatg gcggaagaac aagtccatca gacctggaat cttctgcatc      420

ggcgtggatc tcaacaggaa ctggaagtcg ggttttggag gaaatggttc taacagcaac      480

ccctgctcag aaacttatca cgggccctcc cctcagtcgg agccggaggt ggctgccata      540

gtgaacttca tcacagccca tggcaacttc aaggctctga tctccatcca cagctactct      600

cagatgctta tgtaccctta cggccgattg ctggagcccg tttcaaatca gagggagttg      660

tacgatcttg ccaaggatgc ggtggaggcc ttgtataagg tccatgggat cgagtacatt      720

tttggcagca tcagcaccac cctctatgtg gccagtggga tcaccgtcga ctgggcctat      780

gacagtggca tcaagtacgc cttcagcttt gagctccggg acactgggca gtatggcttc      840

ctgctgccgg ccacacagat catccccacg gcccaggaga cgtggatggc gcttcggacc      900

atcatggagc acaccctgaa tcacccctac                                       930


<210>  5831
<211>  2922
<212>  DNA
<213>  Homo Sapiens

<400>  5831
catgccaagc caggcagcta cagcatcgag gtgctgctgg tggtggacga ctcggtggtt       60

cgcttccatg gcaaggagca tgtgcagaac tatgtcctca ccctcatgaa tatcgtagat      120

gagatttacc acgatgagtc cctgggggtt catataaata ttgccctcgt ccgcttgatc      180

atggttggct accgacagtc cctgagcctg atcgagcgcg ggaacccctc acgcagcctg      240

gagcaggtgt gtcgctgggc acactcccag cagcgccagg accccagcca cgctgagcac      300

catgaccacg ttgtgttcct cacccggcag gactttgggc cctcaggtat gcaagggtat      360

gcacccgtca ctggcatgtg tcaccccctg aggagctgtg ccctcaacca tgaggatggc      420

ttctcctcag ccttcgtgat agctcatgag accggccacg tgctcggcat ggagcatgac      480

ggtcagggga atggctgtgc agatgagacc agcctgggca gcgtcatggc gcccctggtg      540

caggctgcct tccaccgctt ccattggtcc cgctgcagca agctggagct cagccgctac      600

ctcccctcct acgactgcct cctcgatgac ccctttgatc ctgcctggcc ccagccccca      660

gagctgcctg ggatcaacta ctcaatggat gagcagtgcc gctttgactt tggcagtggc      720

taccagacct gcttggcatt caggaccttt gagccctgca agcagctgtg gtgcagccat      780

cctgacaacc cgtacttctg caagaccaag aaggggcccc cgctggatgg gactgagtgt      840

gcacccggca agtggtgctt caaaggtcac tgcatctgga agtcgccgga gcagacatat      900

ggccaggatg gaggctggag ctcctggacc aagtttgggt catgttcgcg gtcatgtggg      960

ggcggggtgc gatcccgcag ccggagctgc aacaacccct ccccagccta tggaggccgc     1020

ctgtgcttag ggcccatgtt cgagtaccag gtctgcaaca gcgaggagtg ccctgggacc     1080

tacgaggact tccgggccca gcagtgtgcc aagcgcaact cctactatgt gcaccagaat     1140

gccaagcaca gctgggtgcc ctacgagcct gacgatgacg cccagaagtg tgagctgatc     1200

tgccagtcgg cggacacggg ggacgtggtg ttcatgaacc aggtggttca cgatgggaca     1260

cgctgcagct accgggaccc atacagcgtc tgtgcgcgtg gcgagtgtgt gcctgtcggc     1320

tgtgacaagg aggtggggtc catgaaggcg gatgacaagt gtggagtctg cgggggtgac     1380

aactcccact gcaggactgt gaaggggacg ctgggcaagg cctccaagca ggcaggagct     1440

ctcaagctgg tgcagatccc agcaggtgcc aggcacatcc agattgaggc actggagaag     1500

tccccccacc gcattgtggt gaagaaccag gtcaccggca gcttcatcct caaccccaag     1560

ggcaaggaag ccacaagccg gaccttcacc gccatgggcc tggagtggga ggatgcggtg     1620

gaggatgcca aggaaagcct caagaccagc gggcccctgc ctgaagccat tgccatcctg     1680

gctctccccc caactgaggg tggcccccgc agcagcctgg cctacaagta cgtcatccat     1740

gaggacctgc tgccccttat cgggagcaac aatgtgctcc tggaggagat ggacacctat     1800

gagtgggcgc tcaagagctg ggccccctgc agcaaggcct gtggaggagg gatccagttc     1860

accaaatacg gctgccggcg cagacgagac caccacatgg tgcagcgaca cctgtgtgac     1920

cacaagaaga ggcccaagcc catccgccgg cgctgcaacc agcacccgtg ctctcagcct     1980

gtgtgggtga cggaggagtg gggtgcctgc agccggagct gtgggaagct gggggtgcag     2040

acacggggga tacagtgcct gctgcccctc tccaatggaa cccacaaggt catgccggcc     2100

aaagcctgcg ccggggaccg gcctgaggcc cgacggccct gtctccgagt gccctgccca     2160

gcccagtgga ggctgggagc ctggtcccag tgctctgcca cctgtggaga gggcatccag     2220

cagcggcagg tggtgtgcag gaccaacgcc aacagcctcg ggcattgcga gggggatagg     2280

ccagacactg tccaggtctg cagcctgccc gcctgtggag gaaatcacca gaactccacg     2340

gtgagggccg atgtctggga acttgggacg ccagaggggc agtgggtgcc acaatctgaa     2400

cccctacatc ccattaacaa gatatcatca acggagccct gcacgggaga caggtctgtc     2460

ttctgccaga tggaagtgct cgatcgctac tgctccattc ccggctacca ccggctctgc     2520

tgtgtgtcct gcatcaagaa ggcctcgggc cccaaccctg gcccagaccc tggcccaacc     2580

tcactgcccc ccttctccac tcctggaagc cccttaccag gaccccagga ccctgcagat     2640

gctgcagagc ctcctggaaa gccaacggga tcagaggacc atcagcatgg ccgagccaca     2700

cagctcccag gagctctgga tacaagctcc ccagggaccc agcatccctt tgcccctgag     2760

acaccaatcc ctggagcatc ctggagcatc tcccctacca cccccggggg gctgccttgg     2820

ggctggactc agacacctac gccagtccct gaggacaaag ggcaacctgg agaagacctg     2880

agacatcccg gcaccagcct ccctgctgcc tccccggtga ca                        2922


<210>  5832
<211>  1257
<212>  DNA
<213>  Homo Sapiens

<400>  5832
atgtctcgaa aaatttcaaa ggagtcaaaa aaagtgaaca tctctagttc tctggaatct       60

gaagatatta gtttagaaac aacagttcct acggatgata tttcctcatc agaagagcga      120

gagggcaaag tcagaatcac caggcagcta attgaacgaa aagaactact tcataatatt      180

cagttactaa aaattgagct atcccagaaa actatgatga tcgacaattt gaaagtggat      240

tatcttacaa agattgaaga attggaggag aaacttaatg atgcacttca ccagaagcag      300

ctactaacat tgagattaga caaccaattg gcttttcaac agaaagatgc cagcaaatat      360

caagaattaa tgaaacaaga aatggaaacc attttgttga gacagaaaca actagaagag      420

acaaatcttc agctaagaga aaaagctgga gatgttcgtc gaaacctgcg tgactttgag      480

ttgacagaag agcaatatgt taaattaaaa gcttttcctg aagatcagct ttctattcct      540

gaatatgtat ctgttcgctt ctatgagcta gtgaatccat taagaaagga aatctgtgaa      600

ctacaagtga aaaagaatat cctagcagaa gaattaagta caaacaaaaa ccaactgaag      660

cagctgacag agacatatga ggaagatcga aaaaactact ctgaagttca aattagatgt      720

caacgtttgg ccttagaatt agcagacaca aaacagttaa ttcagcaagg tgactaccgt      780

caagagaact atgataaagt caagagtgaa cgtgatgcac ttgaacagga agtaattgag      840

cttaggagaa aacatgaaat acttgaagcc tctcacatga ttcaaacaaa agaacgaagt      900

gaattatcaa aagaggtagt caccttagag caaactgtta ctttactgca aaaggataaa      960

gaatatctta atcgccaaaa catggagctt agtgttcgct gtgctcatga agaggatcgc     1020

cttgaaagac ttcaagctca actggaagaa agcaaaaagg ctagagaaga gatgtatgaa     1080

aaatatgtag catccagaga ccattataaa acagaatatg aaaataaact acatgatgaa     1140

ctagaacaaa tcagattgaa aaccaaccaa gaaattgatc aacttcgaaa tgcctctagg     1200

gaaatgtatg aacgagaaaa cagaaatctc cgagaagcaa gggataatgc tgtggct        1257


<210>  5833
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  5833
aatggaatcc agggattctt ctacccatgg agctgtgagg gtgacatatg ggaccgggag       60

agctgtgggg gccaggcggc catcgatagc cccaacctct gcctgcgtct ccggtgctgc      120

taccgcaatg gggtctgcta ccaccagcgt ccagacgaaa acgtgcggag gaagcacatg      180


<210>  5834
<211>  1002
<212>  DNA
<213>  Homo Sapiens

<400>  5834
gcaacaattt catgcagaaa tgaagaaggg aaagctgtgg actggtttac tttttataag       60

ttacctaaaa aacaaaacaa ggaaagtgga gagactgggt tagagtacct gtacctagac      120

tctacaacta gaagctggag gaagagtgag caactaatga atgacaccaa gagtgttttg      180

ggaaggacat tacaacagct atatgaagca tatgcctcta agagtaacaa cacagcctat      240

ctaatataca atgatggagt ccctaaacct gtgaattaca gcagaaagta tggacacacc      300

aaaggtttac tgctgtggaa cagagttcaa gggttctggc tgattcattc catccctcag      360

tttcctccaa ttccggaaga aggctatgat tatccaccca cagggagacg aaatggacaa      420

agtggcatct gcataacttt caagtacaac cagtatgagg caatagattc tcagctcttg      480

gtctgcaacc ccaacgtcta tagctgctcc atcccagcca cctttcacca ggagctcatt      540

cacatgcccc agctgtgcac cagggccagc tcatcagaga ttcctggcag gctcctcacc      600

acacttcagt cggcccaggg acaaaaattc ctccattttg caaagtcgga ttcttttctt      660

gacgacatct ttgcagcctg gatggctcaa cggctgaaga cacacttgtt aacagaaacc      720

tggcagcgaa aaagacaaga gcttccttca aactgctccc ttccttacca tgtctacaat      780

ataaaagcaa ttaaattatc acgacactct tatttcagtt cttatcaaga tcacgccaag      840

tggtgtattt cccaaaaggg caccaaaaat cgctggacat gtattggaga cctaaatcgg      900

agtccacacc aagccttcag aagtggagga ttcatttgta cccagaattg gcaaatttac      960

caagcatttc aaggattagt attatactat gaaagctgta ag                        1002


<210>  5835
<211>  1293
<212>  DNA
<213>  Homo Sapiens

<400>  5835
ctgcccgtgg cgcccgcagg cggcaggaat cctcctccgg cgataggaca gttttggcat       60

gtgactgact tacacttaga ccctacttac cacatcacag atgaccacac aaaagtgtgt      120

gcttcatcta aaggtgcaaa tgcctccaac cctggccctt ttggagatgt tctgtgtgat      180

tctccatatc aacttatttt gtcagcattt gattttatta aaaattctgg acaagaagca      240

tctttcatga tatggacagg ggatagccca cctcatgttc ctgtacctga actctcaaca      300

gacactgtta taaatgtgat cactaatatg acaaccacca tccagagtct ctttccaaat      360

ctccaggttt tccctgcgct gggtaatcat gactattggc cacaggatca actgcctgta      420

gtcaccagta aagtgtacaa tgcagtagca aacctctgga aaccatggct agatgaagaa      480

gctattagta ctttaaggaa aggtggtttt tattcacaga aagttacaac taatccaaac      540

cttaggatca tcagtctaaa cacaaacttg tactacggcc caaatataat gacactgaac      600

aagactgacc cagccaacca gtttgaatgg ctagaaagta cattgaacaa ctctcagcag      660

aataaggaga aggtgtatat catagcacat gttccagtgg ggtatctgcc atcttcacag      720

aacatcacag caatgagaga atactataat gagaaattga tagatatttt tcaaaaatac      780

agtgatgtca ttgcaggaca attttatgga cacactcaca gagacagcat tatggttctt      840

tcagataaaa aaggaagtcc agtaaattct ttgtttgtgg ctcctgctgt tacaccagtg      900

aagagtgttt tagaaaaaca gaccaacaat cctggtatca gactgtttca gtatgatcct      960

cgtgattata aattattgga tatgttgcag tattacttga atctgacaga ggcgaatcta     1020

aagggagagt ccatctggaa gctggagtat atcctgaccc agacctacga cattgaagat     1080

ttgcagccgg aaagtttata tggattagct aaacaattta caatcctaga cagtaagcag     1140

tttataaaat actacaatta cttctttgtg agttatgaca gcagtgtaac atgtgataag     1200

acatgtaagg cctttcagat ttgtgcaatt atgaatcttg ataatatttc ctatgcagat     1260

tgcctcaaac agctttatat aaagcacaat tac                                  1293


<210>  5836
<211>  609
<212>  DNA
<213>  Homo Sapiens

<400>  5836
caagtatttg aaataaaaat ggatgcaagt ttaggaaatc tatttgcaag atcagcattg       60

gacacagctg cacgttctac aaagcctccc agatataagt gtgggatctc aaaagcttgc      120

cctgagaagc attttgcttt taaaatggca agtggagcag ccaacgtggt gggacccaaa      180

atctgcctgg aagataatgt tttaatgagt ggtgttaaga ataatgttgg aagagggatc      240

aatgttgcct tggcaaatgg aaaaacagga gaagtattag acactaaata ttttgacatg      300

tggggaggag atgtggcacc atttattgag tttctgaagg ccatacaaga tggaacaata      360

gttttaatgg gaacatacga tgatggagca accaaactca atgatgaggc acggcggctc      420

attgctgatt tggggagcac atctattact aatcttggtt ttagagacaa ctgggtcttc      480

tgtggtggga agggcattaa gacaaaaagc ccttttgaac agcacataaa gaacaataag      540

gatacaaaca aatatgaagg atggcctgaa gttgtagaaa tggaaggatg catcccccag      600

aagcaagac                                                              609


<210>  5837
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  5837
tccgtgtgcc ccctaccacc ggagccagag aatggtggct acatctgcca cccccggccc       60

tgcagagacc ccctgacagc aggcagtgtc atcgaatacc tgtgtgctga aggctacatg      120

ttgaagggcg attacaaata cctgacgtgt aagaatggcg agtggaaacc agccatggag      180

attagctgcc gtctcaacga ggataaagac acccacacat cacttggggt ccccacgctg      240

tct                                                                    243


<210>  5838
<211>  1908
<212>  DNA
<213>  Homo Sapiens

<400>  5838
aactcagtgg agaggaagat atatatcccc ttaaataaaa cagctccctg tgttcgcctg       60

ctcaacgcca ctcatcagat tggctgccag tcttcaatta gtggagacac aggggttatc      120

cacgtagtag agaaagagga ggacctacag tgggtattga ctgatggccc caacccccct      180

tacatggttc tgctggagag caagcatttt accagggatt taatggagaa gctgaaaggg      240

agaaccagcc gaattgctgg tcttgcagtg tccttgacca agcccagtcc tgcctcaggc      300

ttctctccta gtgtacagtg cccaaatgat gggtttggtg tttactccaa ttcctatggg      360

ccagagtttg ctcactgcag agaaatacag tggaattcgc tgggcaatgg tttggcttat      420

gaagacttta gtttccccat ctttcttctt gaagatgaaa atgaaaccaa agtcatcaag      480

cagtgctatc aagatcacaa cctgagtcag aatggctcag caccaacctt cccactatgt      540

gccatgcagc tcttttcaca catgcatgct gtcatcagca ctgccacctg catgcggcgc      600

agctccatcc aaagcacctt cagcatcaac ccagaaatcg tctgtgaccc cctgtctgat      660

tacaatgtgt ggagcatgct aaagcctata aatacaactg ggacattaaa gcctgacgac      720

agggttgtgg ttgctgccac ccggctggat agtcgttcct ttttctggaa tgtggcccca      780

ggggctgaaa gcgcagtggc ttcctttgtc acccagctgg ctgctgctga agctttgcaa      840

aaggcacctg atgtgaccac cctgccccgc aatgtcatgt ttgtcttctt tcaaggggaa      900

acttttgact acattggcag ctcgaggatg gtctacgata tggagaaggg caagtttccc      960

gtgcagttag agaatgttga ctcatttgtg gagctgggac aggtggcctt aagaacttca     1020

ttagagcttt ggatgcacac agatcctgtt tctcagaaaa atgagtctgt acggaaccag     1080

gtggaggatc tcctggccac attggagaag agtggtgctg gtgtccctgc tgtcatcctc     1140

aggaggccaa atcagtccca gcctctccca ccatcttccc tgcagcgatt tcttcgagct     1200

cgaaacatct ctggcgttgt tctggctgac cactctggtg ccttccataa caaatattac     1260

cagagtattt acgacactgc tgagaacatt aatgtgagct atcccgaatg gctgagccct     1320

gaagaggacc tgaactttgt aacagacact gccaaggccc tggcagatgt ggccacggtg     1380

ctgggacgtg ctctgtatga gcttgcagga ggaaccaact tcagcgacac agttcaggct     1440

gatccccaaa cggttacccg cctgctctat gggttcctga ttaaagccaa caactcatgg     1500

ttccagtcta tcctcaggca ggacctaagg tcctacttgg gtgacgggcc tcttcaacat     1560

tacatcgctg tctccagccc caccaacacc acttatgttg tacagtatgc cttggcaaat     1620

ttgactggca cagtggtcaa cctcacccga gagcagtgcc aggatccaag taaagtccca     1680

agtgaaaaca aggatctgta tgagtactca tgggtccagg gccctttgca ttctaatgag     1740

acggaccgac tcccccggtg tgtgcgttct actgcacgat tagccagggc cttgtctcct     1800

gcctttgaac tgagtcagtg gagctctact gaatactcta catggactga gagccgctgg     1860

aaagatatcc atgcccggat atttctcatc gccagcaaag agcttgag                  1908


<210>  5839
<211>  1206
<212>  DNA
<213>  Homo Sapiens

<400>  5839
gaaggcgacg ccaaggggct caaggagggc gagacccccg gcaatttcat ggaggacgag       60

caatggctgt cgtccatctc gcagtacagc ggcaagatca agcactggaa ccgcttccga      120

gacgaagtgg aggatgacta tatcaagagc tgggaggaca atcagcaagg agatgaagcc      180

ctggatacca ccaaggaccc ctgccagaag gtgaagtgca gccgccacaa ggtgtgcatt      240

gcccagggct accagcgggc catgtgcatc agtcgcaaga agctggagca caggatcaag      300

cagccgaccg tgaaactcca tggaaacaaa gactccatct gcaagccctg ccacatggcc      360

cagcttgcct ctgtctgcgg ctcagatggc cacacttaca gctctgtgtg taagctggag      420

caacaggcgt gcctgagcag caagcagctg gcggtgcgat gcgagggccc ctgcccctgc      480

cccacggagc aggctgccac ctccaccgcc gatggcaaac cagagacttg caccggtcag      540

gacctggctg acctgggaga tcggctgcgg gactggttcc agctccttca tgagaactcc      600

aagcagaatg gctcagccag cagtgtagcc ggcccggcca gcgggctgga caagagcctg      660

ggggccagct gcaaggactc cattggctgg atgttctcca agctggacac cagtgctgac      720

ctcttcctgg accagacgga gctggccgcc atcaacctgg acaagtacga ggtctgcatc      780

cgtcccttct tcaactcctg tgacacctac aaggatggcc gggtctctac tgctgagtgg      840

tgcttctgct tctggaggga gaagcccccc tgcctggcag agctggagcg catccagatc      900

caggaggccg ccaagaagaa gccaggcatc ttcatcccga gctgcgacga ggatggctac      960

taccggaaga tgcagtgtga ccagagcagc ggtgactgct ggtgtgtgga ccagctgggc     1020

ctggagctga ctggcacgcg cacgcatggg agccccgact gcgatgacat cgtgggcttc     1080

tcgggggact ttggaagcgg tgtcggctgg gaggatgagg aggagaagga gacggaggaa     1140

gcaggcgagg aggccgagga ggaggagggc gaggcaggcg aggctgacga cgggggctac     1200

atctgg                                                                1206


<210>  5840
<211>  699
<212>  DNA
<213>  Homo Sapiens

<400>  5840
aaagtcatga acttcacaat tgatggaatg ggaaacctga ggatcacaga aaaaggtcta       60

aagctagaag gagactctga attcttacaa cctctctacg ccaaagaaat ccagtcccga      120

ccaggtaatg ccctgtactt caagtctgcc agaaatgtta cagtgaacat tctcaatgac      180

cagactaaag tgctaactca gcttataaca ggtccaaaag ccgtagaagc ttatggtaaa      240

aaatttgagg taaaaactgt ttctggaaaa ttgctcttct ctgcagacaa taatgaagtg      300

gtagtaggag ctgaaagatt acgagtttta ggagcggagg gcacagtgtt ccctaaatct      360

atagaaacac ctaatgtcag ggcagacccc ttcaaagaac taaggttgga gtccccaacc      420

cggtctctag tgatggaggc cccaaaagga gtggaaatca atgcagaagc tggcaatatg      480

gaagccacct gcaggacaga gctgagactg gaatccaaag atggagagat taagttagat      540

gctgcgaaaa tcaggctacc tagactgcct catggatcct acacgcctac aggaacgagg      600

cagaaggtct tcgagatctg cgtctgcgcc aatgggagat tattcctgtc tcaggcagga      660

gctgggtcca cttgtcagat aaacacaagt gtctgcctc                             699


<210>  5841
<211>  879
<212>  DNA
<213>  Homo Sapiens

<400>  5841
gcagcctgtg agcccgtccg catccccctg tgcaagtccc tgccctggaa catgactaag       60

atgcccaacc acctgcacca cagcactcag gccaacgcca tcctggccat cgagcagttc      120

gaaggtctgc tgggcaccca ctgcagcccc gatctgctct tcttcctctg tgccatgtac      180

gcgcccatct gcaccattga cttccagcac gagcccatca agccctgtaa gtctgtgtgc      240

gagcgggccc ggcagggctg tgagcccata ctcatcaagt accgccactc gtggccggag      300

aacctggcct gcgaggagct gccagtgtac gacaggggcg tgtgcatctc tcccgaggcc      360

atcgttactg cggacggagc tgattttcct atggattcta gtaacggaaa ctgtagaggg      420

gcaagcagtg aacgctgtaa atgtaagcct attagagcta cacagaagac ctatttccgg      480

aacaattaca actatgtcat tcgggctaaa gttaaagaga taaagactaa gtgccatgat      540

gtgactgcag tagtggaggt gaaggagatt ctaaagtcct ctctggtaaa cattccacgg      600

gacactgtca acctctatac cagctctggc tgcctctgcc ctccacttaa tgttaatgag      660

gaatatatca tcatgggcta tgaagatgag gaacgttcca gattactctt ggtggaaggc      720

tctatagctg agaagtggaa ggatcgactc ggtaaaaaag ttaagcgctg ggatatgaag      780

cttcgtcatc ttggactcag taaaagtgat tctagcaata gtgattccac tcagagtcag      840

aagtctggca ggaactcgaa cccccggcaa gcacgcaac                             879


<210>  5842
<211>  885
<212>  DNA
<213>  Homo Sapiens

<400>  5842
ctgcccgcca gcaatgccct tgtcttcatc accggctgtg actcaggctt tgggcgcctt       60

ctggcactgc agctggacca gagaggcttc cgagtcctgg ccagctgcct gaccccctcc      120

ggggccgagg acctgcagcg ggtggcctcc tcccgcctcc acaccaccct gttggatatc      180

actgatcccc agagcgtcca gcaggcagcc aagtgggtgg agatgcacgt taaggaagca      240

gggctttttg gtctggtgaa taatgctggt gtggctggta tcatcggacc cacaccatgg      300

ctgacccggg acgatttcca gcgggtgctg aatgtgaaca caatgggtcc catcggggtc      360

acccttgccc tgctgcctct gctgcagcaa gcccggggcc gggtgatcaa catcaccagc      420

gtcctgggtc gcctggcagc caatggtggg ggctactgtg tctccaaatt tggcctggag      480

gccttctctg acagcctgag gcgggatgta gctcattttg ggatacgagt ctccatcgtg      540

gagcctggct tcttccgaac ccctgtgacc aacctggaga gtctggagaa aaccctgcag      600

gcctgctggg cacggctgcc tcctgccaca caggcccact atgggggggc cttcctcacc      660

aagtacctga aaatgcaaca gcgcatcatg aacctgatct gtgacccgga cctaaccaag      720

gtgagccgat gcctggagca tgccctgact gctcgacacc cccgaacccg ctacagccca      780

ggttgggatg ccaagctgct ctggctgcct gcctcctacc tgccagccag cctggtggat      840

gctgtgctca cctgggtcct tcccaagcct gcccaagcag tctac                      885


<210>  5843
<211>  882
<212>  DNA
<213>  Homo Sapiens

<400>  5843
agaccccacg gcgacaccgc caagaagccc atcatcggaa tattaatgca aaaatgccgt       60

aataaagtca tgaaaaacta tggaagatac tatattgctg cgtcctatgt aaagtacttg      120

gagtctgcag gtgcgagagt tgtaccagta aggctggatc ttacagagaa agactatgaa      180

atacttttca aatctattaa tggaatcctt ttccctggag gaagtgttga cctcagacgc      240

tcagattatg ctaaagtggc caaaatattt tataacttgt ccatacagag ttttgatgat      300

ggagactatt ttcctgtgtg gggcacatgc cttggatttg aagagctttc actgctgatt      360

agtggagagt gcttattaac tgccacagat actgttgacg tggcaatgcc gctgaacttc      420

actggaggtc aattgcacag cagaatgttc cagaattttc ctactgagtt gttgctgtca      480

ttagcagtag aacctctgac tgccaatttc cataagtgga gcctctccgt gaagaatttt      540

acaatgaatg aaaagttaaa gaagtttttc aatgtcttaa ctacaaatac agatggcaag      600

attgagttta tttcaacaat ggaaggatat aagtatccag tatatggtgt ccagtggcat      660

ccagagaaag caccttatga gtggaagaat ttggatggca tttcccatgc acctaatgct      720

gtgaaaaccg cattttattt agcagagttt tttgttaatg aagctcggaa aaacaaccat      780

cattttaaat ctgaatctga agaggagaaa gcattgattt atcagttcag tccaatttat      840

actggaaata tttcttcatt tcagcaatgt tacatatttg at                         882


<210>  5844
<211>  837
<212>  DNA
<213>  Homo Sapiens

<400>  5844
gcgcttcgca tcggagcctt caacattcag agcttcggtg acagcaaagt gtcggacccc       60

gcttgcggca gcatcatcgc gaagatcctg gctggctatg acctcgcgct ggtgcaggag      120

gtgcgagacc cagacctcag cgccgtgtcc gcgctcatgg agcagatcaa cagcgtgtcc      180

gagcacgagt acagctttgt gagcagccag cccctgggcc gggaccagta caaggagatg      240

tacctgttcg tgtacaggaa agacgcggtg tcggtcgtgg acacctacct gtacccagac      300

cccgaggacg tcttcagccg cgagcccttc gtggtcaagt tctcggcccc cggcaccggt      360

gagcgggccc cgcccctccc ctcccgccga gctctgacgc ccccacccct tcccgcagca      420

gcacagaacc tggtgctgat cccgctgcac gcggcgccgc atcaagccgt ggcggagatc      480

gacgcgctct acgacgtgta cctggacgtg atcgacaagt ggggcaccga cgacatgctg      540

ttcctgggcg acttcaacgc cgactgcagc tatgtgcggg cgcaggactg ggccgccatc      600

cgtctgagga gcagtgaggt cttcaagtgg ctcatccctg acagcgccga caccacggtg      660

ggcaactcag actgcgccta cgaccgcatt gtggcctgtg gcgcccgcct gcgccggagc      720

ctgaagcccc agtcggccac cgtgcacgac ttccaggagg aattcggcct ggaccagact      780

caggctcttg ccatcagcga ccactttcca gtggaggtga ccctcaagtt ccaccga         837


<210>  5845
<211>  669
<212>  DNA
<213>  Homo Sapiens

<400>  5845
ttggtgcatg gcggaccctg cgacaagaca tctcacccct accaagctgc cctctacacc       60

tcgggccact tgctctgtgg tggggtcctt atccatccac tgtgggtcct cacagctgcc      120

cactgcaaaa aaccgaatct tcaggtcttc ctggggaagc ataaccttcg gcaaagggag      180

agttcccagg agcagagttc tgttgtccgg gctgtgatcc accctgacta tgatgccgcc      240

agccatgacc aggacatcat gctgttgcgc ctggcacgcc cagccaaact ctctgaactc      300

atccagcccc ttcccctgga gagggactgc tcagccaaca ccaccagctg ccacatcctg      360

ggctggggca agacagcaga tggtgatttc cctgacacca tccagtgtgc atacatccac      420

ctggtgtccc gtgaggagtg tgagcatgcc taccctggcc agatcaccca gaacatgttg      480

tgtgctgggg atgagaagta cgggaaggat tcctgccagg gtgattctgg gggtccgctg      540

gtatgtggag accacctccg aggccttgtg tcatggggta acatcccctg tggatcaaag      600

gagaagccag gagtctacac caacgtctgc agatacacga actggatcca aaaaaccatt      660

caggccaag                                                              669


<210>  5846
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  5846
tacccaccca gcgagcagac catgagggtc ctgccatcgt cggctgcccg ctgcgtggct       60

ctctcagtca acgcctctgg cctcctggac ccggctctcc tccctgctaa cgactccagc      120

agggccccca gctcaggaat ggacgccagc cgacccgcct tagctgacag cttctatgcc      180


<210>  5847
<211>  1695
<212>  DNA
<213>  Homo Sapiens

<400>  5847
gccgcccctt cgtccgtccc ccgcggccgg cagctcccgg ggcgtctggg ctgcctgctc       60

gaggagggcc tctgcggagc gtccgaggcc tgtgtgaacg atggagtgtt tggaaggtgc      120

cagaaggttc cggcaatgga cttttaccgc tacgaggtgt cgcccgtggc cctgcagcgc      180

ctgcgcgtgg cgttgcagaa gctttccggc acaggtttca cgtggcagga tgactatact      240

cagtatgtga tggaccagga acttgcagac ctcccgaaaa cctacctgag gcgtcctgaa      300

gcatccagcc cagccaggcc ctcaaaacac agcgttggca gcgagaggag gtacagtcgg      360

gagggcggtg ctgccctggc caacgccctc cgacgccacc tgcccttcct ggaggccctg      420

tcccaggccc cagcctcaga cgtgctcgcc aggacccata cggcgcagga cagacccccc      480

gctgagggtg atgaccgctt ctccgagagc atcctgacct atgtggccca cacgtctgcg      540

ctgacctacc ctcccgggcc ccggacccag ctccgcgagg acctcctgcc gcggaccctc      600

ggccagctcc agccagatga gctcagccct aaggtggaca gtggtgtgga cagacaccat      660

ctgatggcgg ccctcagtgc ctatgctgcc cagaggcccc cagctccccc cggggagggc      720

agcctggagc cacagtacct tctgcgtgca ccctcaagaa tgcccaggcc tttgctggca      780

ccagccgccc cccagaagtg gccttcacct ctgggagatt ccgaagaccc ctctagcaca      840

ggcgatggag cacggattca taccctcctg aaggacctgc agaggcagcc ggctgaggtg      900

aggggcctga gtggcctgga gctggacggc atggctgagc tgatggctgg cctgatgcaa      960

ggcgtggacc atggagtagc tcgaggcagc cctgggagag cggccctggg agagtctgga     1020

gaacaggcgg atggccccaa ggccaccctc cgtggagaca gctttccaga tgacggagtg     1080

caggacgacg atgatagact ttaccaagag gtccatcgtc tgagtgccac actcgggggc     1140

ctcctgcagg accacgggtc tcgactctta cctggagccc tcccctttgc aaggcccctc     1200

gacatggaga ggaagaagtc cgagcaccct gagtcttccc tgtcttcaga agaggagact     1260

gccggagtgg agaacgtcaa gagccagacg tattccaaag atctgctggg gcagcagccg     1320

cattcggagc ccggggccgc tgcgtttggg gagctccaaa accagatgcc tgggccctcg     1380

aaggaggagc agagccttcc agcgggtgct caggaggccc tcagcgacgg cctgcaattg     1440

gaggtccagc cttccgagga agaggcgcgg ggctacatcg tgacagacag agaggttctc     1500

ggaccagcag tgaccttcaa agtgagcgcc aatgtccaaa acgtgaccac tgaggatgtg     1560

gagaaggcca cagttgacaa caaagacaaa ctggaggaaa cctctggact gaaaattctt     1620

caaaccggag tcgggtcgaa aagcaaactc aagttcctgc ctcctcaggc ggagcaagaa     1680

gactccacca agttc                                                      1695


<210>  5848
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5848
ttcttcatgg gatgctccac cccaactgtg gccgaagtct acccccctag cacatcaagt       60

tctatacatc cgcagtctcc tgcctgccgc agggactgct cgtgcccaga ttctatcttc      120

cacccggtct gtggagacaa tggaatcgag tacctctccc cttgccatgc cggctgcagc      180

aacatcaaca tgagctctgc aacctccaag caactgatct atttgaactg cagctgtgtg      240

accgggggat ccgcttcagc aaagacagga tcgtgccctg tcccctgtgc ccacttcctg      300

ctcccggcc                                                              309


<210>  5849
<211>  240
<212>  DNA
<213>  Homo Sapiens

<400>  5849
atggactcgg gaaccgagga gtacgagctc aacggcggcc tgcctccggg cacacccggc       60

tccccggacg cctcgccggc ccgctggggc tggaggcacg ggcccatcaa cgtgaaccat      120

tacgccagca agaagagcgc agccgagagc atgctggaca tcgcgctgct gatggccaac      180

gcgtcccagc tgaaggccgt cgtggaacag ggccccagct tcgccttcta tgtgcccctg      240


<210>  5850
<211>  717
<212>  DNA
<213>  Homo Sapiens

<400>  5850
tctgaggttg caattaaaat cgacttcgac ttcgcaccag gttcttttga tgatcagtac       60

caaggctgta gcaaacaggt tatggagaaa ctaactcaag gggattattt cacaaaagac      120

atagaagccc agaagaatta ttttaggatg tggcaaaaag cccacttagc ctggcttaac      180

caaggaaaag ttctacccca gaacatgact accacacacg ctgtggctat tttgttttac      240

acattgaaca gcaatgttca ttctgacttt actagagcca tggcctctgt tgccaggact      300

ccacagcagt atgaacgttc attccacttc aaatatttac actactacct cacctcagca      360

atccagctgc tgaggaaaga cagcatcatg gagaatggca ctctgtgcta tgaggtgcat      420

tataggacga aggatgtcca ctttaatgcc tacacagggg ccaccattcg atttggccaa      480

ttcctttcca catccctcct gaaagaagag gcacaggagt ttgggaacca gacactattt      540

accatattca cctgcctggg tgcacctgta cagtacttct ccctcaagaa ggaagtcttg      600

atccctccct atgagctgtt taaagttata aatatgagct accacccaag aggaaactgg      660

ttgcagttga ggtcaactgg gaacctgagc acatataact gtcagctgct aaaagct         717


<210>  5851
<211>  804
<212>  DNA
<213>  Homo Sapiens

<400>  5851
aagaagggtt accaagacgt cgacacctcc ctgcagagtg ctgtcatcac caaagtcaag       60

ggcgtggcct tcaccaacac ctcggatctt gggcagcgga tctgggatgt cgccgactac      120

gtcattccag cccagggaga gaacgtcttt tttgtggtca ccaacctgat tgtgaccccc      180

aaccagcggc agaacgtctg tgctgagaat gaaggcattc ctgatggcgc gtgctccaag      240

gacagcgact gccacgctgg ggaagcggtt acagctggaa acggagtgaa gaccggccgc      300

tgcctgcgga gagagaactt ggccaggggc acctgtgaga tctttgcctg gtgcccgttg      360

gagacaagct ccaggccgga ggagccattc ctgaaggagg ccgaagactt caccattttc      420

ataaagaacc acatccgttt ccccaaattc aacttctcca aaagcaatgt gatggacgtc      480

aaggacagat ctttcctgaa atcatgccac tttggcccca agaaccacta ctgccccatc      540

ttccgactgg gctccgtgat ccgctgggcc gggagcgact tccaggatat agccctggag      600

ggtggcgtga taggaattaa tattgaatgg aactgtgatc ttgataaagc tgcctctgag      660

tgccaccctc actattcttt tagccgtctg gacaataaac tttcaaagtc tgtctcctcc      720

gggtacaact tcagatttgc cagatattac cgagacgcag ccggggtgga gttccgcacc      780

ctgatgaaag cctacgggat ccgc                                             804


<210>  5852
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5852
tggcctaagc gtctcaccaa ggctcactgg tttgaaattc agcatataca gccaagtcct       60

ctccaatgca acagggcaat gagtggcatc aacaattata cccagcactg taagcatcaa      120

aatacctttc tgcatgactc tttccagaat gtggctgctg tctgtgattt gctcagcatt      180

gtctgcaaaa atcgtcggca caactgccac cagagctcaa agcctgtcaa catgactgac      240

tgcagactca cttcaggaaa gtatccccag tgccgctata gtgctgctgc ccagtacaaa      300

ttcttcattg ttgcctgtga cccccctcag aagagcgatc ccccctacaa gttggttcct      360

gtacacttag atagtattct c                                                381


<210>  5853
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  5853
tggtcggtga acaatttcct gatgactggt ccaaaggctt acctgattta ctccagcagt       60

gtggcagctg gtgcccagag tggtattgaa gaatgcaagt atcagtttgc ctgggaccgc      120

tggaactgcc ctgagagagc cctgcagctg tccagccatg gtgggcttcg cagtgccaat      180

cgggagacag catttgtgca tgccatcagt tctgctggag tcatgtacac cctgactaga      240

aactgcagcc ttggagattt tgataactgt ggctgtgatg actcccgcaa cgggcaactg      300

gggggacaag gctggctgtg gggaggctgc agtgacaatg tgggcttcgg agaggcgatt      360

tccaagcagt ttgtcgatgc cctggaaaca ggacaggatg cacgggcagc catgaacctg      420

cacaacaacg aggctggccg caaggcggtg aagggcacca tgaaacgcac gtgcaagtgc      480

cacggcgtgt ctggcagctg caccacgcag acctgttggc tgcagctgcc cgagttccgc      540

gaggtgggcg cgcacctgaa ggagaagtac cacgcagcac tcaaggtgga cctgctgcag      600

ggtgctggca acagcgcggc cggccgcggc gccatcgccg acacctttcg ctccatctct      660

acccgggagc tggtgcacct ggaggactcc ccggactact gcctggagaa caaaacgcta      720

gggctgctgg gcaccgaagg ccgagagtgc ctaaggcgcg ggcgggccct gggtcgctgg      780

gaacgccgca gctgccgccg gctctgcggg gactgcgggc tggcggtgga ggagcgccgg      840

gccgagaccg tgtccagctg caactgcaag ttccactggt gctgcgcagt ccgctgcgag      900

cagtgccgcc ggagggtcac caagtacttc tgtagccgcg cagagcggcc gcgggggggc      960

gctgcgcaca aacccgggag aaaaccc                                          987


<210>  5854
<211>  345
<212>  DNA
<213>  Homo Sapiens

<400>  5854
aagtttgatg attttgagga tgaggaggac atagtagagt atgatgataa tgacttcgct       60

gaatttgagg atgtcatgga agactctgtt actgaatctc ctcaacgggt cataatcact      120

gaagatgatg aagatgagac cactgtggag ttggaagggc aggatgaaaa ccaagaagga      180

gattttgaag atgcagatac ccaggaggga gatactgaga gtgaaccata tgatgatgaa      240

gaatttgaag gttatgaaga caaaccagat acttcttcta gcaaaaataa agacccaata      300

acgattgttg atgttcctgc acacctccag aacagctggg agagt                      345


<210>  5855
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  5855
tggagcatcg gggcagctcc gttctccgga cgcaggaact ggtgctccta tgtggtgacc       60

cgcaccatct catgccatgt gcagaatggc acctaccttc agcgagtgct gcagaactgc      120

ccctggccca tgagctgtcc ggggagcagc tacagaactg tggtgagacc cacatacaag      180

gtgatgtaca agatagtgac cgcccgtgag tggaggtgct gccctgggca ctcaggagtg      240

agctgcgagg aagttgcagc ttcctctgcc tccttggagc ccatgtggtc gggcagtacc      300

atgcggcgga tggcgcttcg gcccacagcc ttctcaggtt gtctcaactg cagcaaagtg      360

tcagagctga cagagcggct gaaggtgctg gaggccaaga tgaccatgct gactgtcata      420

gagcagccag tacctccaac accagctacc cctgaggacc ctgccccgct ctggggtccc      480

cctcctgccc agggcagccc cggagatgga ggcctccagg accaagtcgg tgcttggggg      540

cttcccgggc ccaccggccc caagggagat gccggcagtc ggggcccaat ggggatgaga      600

ggcccaccag gtccacaggg ccccccaggg agccctggcc gggctggagc tgtgggcacc      660

cctggagaga ggggacctcc tgggccacca gggcctcctg gcccccctgg gcccccagcc      720

cctgttgggc caccccatgc ccggatctcc cagcatggag acccattgct gtccaacacc      780

ttcactgaga ccaacaacca ctggccccag ggacccactg ggcctccagg ccctccaggg      840

cccatgggtc cccctgggcc tcctggcccc acaggtgtcc ctgggagtcc tggtcacata      900

ggacccccag gccccactgg acccaaagga atctctggcc acccaggaga gaagggcgag      960

agaggactgc gtggggagcc tggcccccaa ggctctgctg ggcagcgggg ggaacctggc     1020

cctaagggag accctggtga gaagagccac tggggggagg ggttgcacca gctacgcgag     1080

gctttgaaga ttttagctga gagggtttta atcttggaaa caatgattgg gctctatgaa     1140

ccagagctgg ggtctggggc gggccctgcc ggcacaggca cccccagcct ccttcggggc     1200

aagaggggcg gacatgcaac caactaccgg atcgtggccc ccaggagccg ggacgagaga     1260

ggc                                                                   1263


<210>  5856
<211>  1668
<212>  DNA
<213>  Homo Sapiens

<400>  5856
gtggggaggg ggctgggccg cgccagcccg gccgggggcc ccctggaaga tgtggtcatc       60

gagaggtacc acatccccag ggcctgtccc cgggaagtgc agatggggga ttttgtgcgc      120

taccactaca acggcacttt tgaagatggc aagaagtttg attcaagcta tgatcgcaac      180

accttggtgg ccatcgtggt gggtgtgggg cgcctcatca ctggcatgga ccgaggcctc      240

atgggcatgt gtgtcaacga gcggcgacgc ctcattgtgc ctccccacct gggctatggg      300

agcatcggcc tggcggggct cattccaccg gatgccaccc tctacttcga tgtggttctg      360

ctggatgtgt ggaacaagga agacaccgtg caggtgagca cattgctgcg cccgccccac      420

tgcccccgca tggtccagga cggcgacttt gtccgctacc actacaatgg caccctgctg      480

gacggcacct ccttcgacac cagctacagt aagggcggca cttatgacac ctacgtcggc      540

tctggttggc tgatcaaggg catggaccag gggctgctgg gcatgtgtcc tggagagaga      600

aggaagatta tcatccctcc attcctggcc tatggcgaga aaggctatgg gacagtgatc      660

cccccacagg cctcgctggt ctttcacgtc ctcctgattg acgtgcacaa cccgaaggac      720

gctgtccagc tagagacgct ggagctcccc cccggctgtg tccgcagagc cggggccggg      780

gacttcatgc gctaccacta caatggctcc ttgatggacg gcaccctctt cgattccagc      840

tactcccgca accacaccta caatacctat atcgggcagg gttacatcat ccccgggatg      900

gaccaggggc tgcagggtgc ctgcatgggg gaacgccgga gaattaccat ccccccgcac      960

ctcgcctatg gggagaatgg aactggagac aagatccctg gctctgccgt gctaatcttc     1020

aacgtccatg tcattgactt ccacaaccct gcggatgtgg tggaaatcag gacactgtcc     1080

cggccatctg agacctgcaa tgagaccacc aagcttgggg actttgttcg ataccattac     1140

aactgttctt tgctggacgg cacccagctg ttcacctcgc atgactacgg ggccccccag     1200

gaggcgactc tcggggccaa caaggtgatc gaaggcctgg acacgggcct gcagggcatg     1260

tgtgtgggag agaggcggca gctcatcgtg cccccgcacc tggcccacgg ggagagtgga     1320

gcccggggag tcccaggcag tgctgtgctg ctgtttgagg tggagctggt gtcccgggag     1380

gatgggctgc ccacaggcta cctgtttgtg tggcacaagg accctcctgc caacctgttt     1440

gaagacatgg acctcaacaa ggatggcgag gtccctccgg aggagttctc caccttcatc     1500

aaggctcaag tgagtgaggg caaaggacgc ctcatgcctg ggcaggaccc tgagaaaacc     1560

ataggagaca tgttccagaa ccaggaccgc aaccaggacg gcaagatcac agtcgacgag     1620

ctcaagctga agtcagatga ggacgaggag cgggtccacg aggagctc                  1668


<210>  5857
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  5857
accctggcgc ccggctggcg gctggtgaag ggcttcctga accagccagt ggacgtggag       60

ttgtaccagg gcctgtggga catgtgtcgc gagcagagca gccgcgagcg cgagtgcggc      120

cagacggacc agtggggcta cttcgaggcc cagcccgtgc tggtggcgcg g               171


<210>  5858
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  5858
ccacacctca ggactttcac cgaccgcttc cagacctgca aggtgcaggg cgcctggccg       60

ctcatcgaca ataattacct gaacgtgcag gtcaccaaca cgcctgtgct gcccggctca      120

gcggccactg ccaccagcaa gctcaccatc atcttcaaga acttccagga gtgtgtggac      180

cagaaggtgt accaggctga gatggacgag ctcccggccg ccttcgtgga tggctctaag      240

aacggtgggg acaagcacgg ggccaacagc ctgaagatca ctgagaaggt gtcaggccag      300

cacgtggaga tccaggccaa gtacatcggc accaccatcg tggtgcgcca ggtgggccgc      360

tacctgacct ttgccgtccg catgccagag gaagtggtca atgctgtgga ggactgggac      420

agccagggtc tctacctctg cctgcggggc tgccccctca accagcagat cgacttccag      480

gccttccaca ccaatgctga gggcaccggt gcccgcaggc tggcagccgc cagccctgca      540

cccacagccc ccgagacctt cccatacgag acagccgtgg ccaagtgcaa ggagaagctg      600

ccggtggagg acctgtacta ccaggcctgc gtcttcgacc tcctcaccac gggcgacgtg      660

aacttcacac tggccgccta ctacgcgttg gaggatgtca agatgctcca ctccaacaaa      720

gacaaactgc acctgtatga gaggactcgg gacctgccag gcagggcg                   768


<210>  5859
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  5859
ttctcactgc actgccccag tgtgcccatg gcgggcgtca cagccagcta cggcgggagc       60

ctcctgcccg aaggccacct gaacctaacg gctccctgca acgctgcctg cagctgccag      120

ccagaacact acagccctgt gtgcggctcg gacggcctca tgtacttctc actgtgccac      180

gcagggtgcc ctgcagccac ggagacgaat gtggacggcc agaaggtgta ccgagactgt      240

agctgtatcc ctcagaatct ttcctctggt tttggccatg ccactgcagg gaaatgcact      300

tcaacttgtc agagaaagcc cctcctt                                          327


<210>  5860
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  5860
tacatgagct tcagcatgaa aaccatccgt ctgccacgct ggctggcagc ctcgcccacc       60

aaggagatcc aggttaaaaa gtacaagtgt ggcctcatca agccctgccc agccaactac      120

tttgcgttta aaatctgcag tggggccgcc aacgtcgtgg gccctactat gtgctttgaa      180

gaccgcatga tcatgagtcc tgtgaaaaac aatgtgggca gaggcctaaa catcgccctg      240

gtgaatggaa ccacgggagc tgtgctggga cagaaggcat ttgacatgta ctctggagat      300

gttatgcacc tagtgaaatt ccttaaagaa attccggggg gtgcactggt gctggtggcc      360

tcctacgacg atccagggac caaaatgaac gatgaaagca ggaaactctt ctctgacttg      420

gggagttcct acgcaaaaca actgggcttc cgggacagct gggtcttcat aggagccaaa      480

gacctcaggg gtaaaagccc ctttgagcag ttcttaaaga acagcccaga cacaaacaaa      540

tacgagggat ggccagagct gctggagatg gagggctgca tgcccccgaa gccattt         597


<210>  5861
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  5861
tctgagatcc ccaaggggaa gcaaaaggcg cagctccggc agagggaggt ggtggacctg       60

tataatggaa tgtgcttaca agggccagca ggagtgcctg gtcgagacgg gagccctggg      120

gccaatggca ttccgggtac acctgggatc ccaggtcggg atggattcaa aggagaaaag      180

ggggaatgtc tgagggaaag ctttgaggag tcctggacac ccaactacaa gcagtgttca      240

tggagttcat tgaattatgg catagatctt gggaaaattg cggagtgtac atttacaaag      300

atgcgttcaa atagtgctct aagagttttg ttcagtggct cacttcggct aaaatgcaga      360

aatgcatgct gtcagcgttg gtatttcaca ttcaatggag ctgaatgttc aggacctctt      420

cccattgaag ctataattta tttggaccaa ggaagccctg aaatgaattc aacaattaat      480

attcatcgca cttcttctgt ggaaggactt tgtgaaggaa ttggtgctgg attagtggat      540

gttgctatct gggttggcac ttgttcagat tacccaaaag gagatgcttc tactggatgg      600

aattcagttt ctcgcatcat tattgaagaa ctaccaaaa                             639


<210>  5862
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  5862
aagccatccc cagacgcagg ccctcatggc caggggaggg tgcaccaggc ggcccccctg       60

agcgacgctc cccatgatga cgcccacggg aacttccagt acgaccatga ggctttcctg      120

ggacgggaag tggccaagga attcgaccaa ctcaccccag aggaaagcca ggcccgtctg      180

gggcggatcg tggaccgcat ggaccgcgcg ggggacggcg acggctgggt gtcgctggcc      240

gagcttcgcg cgtggatcgc gcacacgcag cagcggcaca tacgggactc ggtgagcgcg      300

gcctgggaca cgtacgacac ggaccgcgac gggcgtgtgg gttgggagga gctgcgcaac      360

gccacctatg gccactacgc gcccggtgaa gaatttcatg acgtggagga tgcagagacc      420

tacaaaaaga tgctggctcg ggacgagcgg cgtttccggg tggccgacca ggatggggac      480

tcgatggcca ctcgagagga gctgacagcc ttcctgcacc ccgaggagtt ccctcacatg      540

cgggacatcg tgattgctga aaccctggag gacctggaca gaaacaaaga tggctatgtc      600

caggtggagg agtacatcgc ggatctgtac tcagccgagc ctggggagga ggagccggcg      660

tgggtgcaga cggagaggca gcagttccgg gacttccggg atctgaacaa ggatgggcac      720

ctggatggga gtgaggtggg ccactgggtg ctgccccctg cccaggacca gcccctggtg      780

gaagccaacc acctgctgca cgagagcgac acggacaagg atgggcggct gagcaaagcg      840

gaaatcctgg gtaattggaa catgtttgtg ggcagtcagg ccaccaacta tggcgaggac      900

ctgacccggc accacgatga gctg                                             924


<210>  5863
<211>  468
<212>  DNA
<213>  Homo Sapiens

<400>  5863
gggaagatgt atggccctgg aggaggcaag tatttcagca ccactgaaga ctacgaccat       60

gaaatcacag ggctgcgggt gtctgtaggt cttctcctgg tgaaaagtgt ccaggtgaaa      120

cttggagact cctgggacgt gaaactggga gccttaggtg ggaataccca ggaagtcacc      180

ctgcagccag gcgaatacat cacaaaagtc tttgtcgcct tccaagcttt cctccggggt      240

atggtcatgt acaccagcaa ggaccgctat ttctattttg ggaagcttga tggccagatc      300

tcctctgcct accccagcca agaggggcag gtgctggtgg gcatctatgg ccagtatcaa      360

ctccttggca tcaagagcat tggctttgaa tggaattatc cactagagga gccgaccact      420

gagccaccag ttaatctcac atactcagca aactcacccg tgggtcgc                   468


<210>  5864
<211>  372
<212>  DNA
<213>  Homo Sapiens

<400>  5864
cagacgttga aagataccac gtccagttct tcagcagact caactatcat ggacattcag       60

gtcccgacac gagccccaga tgcagtctac acagaactcc agcccacctc tccaacccca      120

acctggcctg ctgatgaaac accacaaccc cagacccaga cccagcaact ggaaggaacg      180

gatgggcctc tagtgacaga tccagagaca cacaagagca ccaaagcagc tcatcccact      240

gatgacacca cgacgctctc tgagagacca tccccaagca cagacgtcca gacagacccc      300

cagaccctca agccatctgg ttttcatgag gatgacccct tcttctatga tgaacacacc      360

ctccggaaac gg                                                          372


<210>  5865
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  5865
ggcgaggact gcctgtggta cctggaccgg aatggctcct ggcatccggg gtttaactgc       60

gagttcttca ccttctgctg cgggacctgc taccatcggt actgctgcag ggacctgacc      120

ttgcttatca ccgagaggca gcagaagcac tgcctggcct tcagccccaa gaccatagca      180


<210>  5866
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  5866
gaagttgaga aatcctcaga tggtcctggt gctgcccagg aacccacgtg gctcacagat       60

gtcccagctg ccatggaatt cattgctgcc actgaggtgg ctgtcatagg cttcttccag      120

gatttagaaa taccagcagt gcccatactc catagcatgg tgcaaaaatt cccaggcgtg      180

tcatttggga tcagcactga ttctgaggtt ctgacacact acaacatcac tgggaacacc      240

atctgcctct ttcgcctggt agacaatgaa caactgaatt tagaggacga agacattgaa      300

agcattgatg ccaccaaatt gagccgtttc attgagatca acagcctcca catggtgaca      360

gagtacaacc ctgtgactgt gattgggtta ttcaacagcg taattcagat tcatctcctc      420

ctgataatga acaaggcctc cccagagtat gaagagaaca tgcacagata ccagaaggca      480

gccaagctct tccaggggaa gattctcttt attctggtgg acagtggtat gaaagaaaat      540

gggaaggtga tatcattttt caaactaaag gagtctcaac tgccagcttt ggcaatttac      600

cagactctag atgacgagtg ggatacactg cccacagcag aagtttccgt agagcatgtg      660

caaaactttt gtgatggatt cctaagtgga aaattgttga aagaaaatcg tgaatcagaa      720

ggaaagactc caaaggtgga actc                                             744


<210>  5867
<211>  693
<212>  DNA
<213>  Homo Sapiens

<400>  5867
gagtctcttc ttgacaatct tggcaatgac ctaagcaatg tcgtggataa gctggaacct       60

gttcttcacg agggacttga gacagttgac aatactctta aaggcatcct tgagaaactg      120

aaggtcgacc taggagtgct tcagaaatcc agtgcttggc aactggccaa gcagaaggcc      180

caggaagctg agaaattgct gaacaatgtc atttctaagc tgcttccaac taacacggac      240

atttttgggt tgaaaatcag caactccctc atcctggatg tcaaagctga accgatcgat      300

gatggcaaag gccttaacct gagcttccct gtcaccgcga atgtcactgt ggccgggccc      360

atcattggcc agattatcaa cctgaaagcc tccttggacc tcctgaccgc agtcacaatt      420

gaaactgatc cccagacaca ccagcctgtt gccgtcctgg gagaatgcgc cagtgaccca      480

accagcatct cactttcctt gctggacaaa cacagccaaa tcatcaacaa gttcgtgaat      540

agcgtgatca acacgctgaa aagcactgta tcctccctgc tgcagaagga gatatgtcca      600

ctgatccgca tcttcatcca ctccctggat gtgaatgtca ttcagcaggt cgtcgataat      660

cctcagcaca aaacccagct gcaaaccctc atc                                   693


<210>  5868
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  5868
aatccgacaa cagctgctcc agctgacacg tatccagcta ctggtcctgc tgatgatgaa       60

gcccctgatg ctgaaaccac tgctgctgca accactgcga ccactgctgc tcctaccact      120

gcaaccaccg ctgcttctac cactgctcgt aaagacattc cagttttacc caaatgggtt      180

ggggatctcc cgaatggtag agtgtgtccc                                       210


<210>  5869
<211>  1680
<212>  DNA
<213>  Homo Sapiens

<400>  5869
cagggtctgt tgttgactct cgaagagcac atagcccact tcctagggac tggaggtgcc       60

gctactacca tgggtaattc ctgtatctgc cgagatgaca gtggaacaga tgacagtgtt      120

gacacccaac agcaacaggc cgagaacagt gcagtaccca ctgctgacac aaggagccaa      180

ccacgggacc ctgttcggcc accaaggagg ggccgaggac ctcatgagcc aaggagaaag      240

aaacaaaatg tggatgggct agtgttggac acactggcag taatacggac tcttgtagat      300

aatgatcagg aacctcccta ttcaatgata acattacacg aaatggcaga aacagatgaa      360

ggatggttgg atgttgtcca gtctttaatt agagttattc cactggaaga tccactggga      420

ccagctgtta taacattgtt actagatgaa tgtccattgc ccactaaaga tgcactccag      480

aaattgactg aaattctcaa tttaaatgga gaagtagctt gccaggactc aagccatcct      540

gccaaacaca ggaacacatc tgcagtccta ggctgcttgg ccgagaaact agcaggtcct      600

gcaagtatag gtttacttag cccaggaata ctggaatact tgctacagtg tctgaagtta      660

cagtcccacc ccacagtcat gctttttgca cttatcgcac tggaaaagtt tgcacagaca      720

agtgaaaata aattgactat ttctgaatcc agtattagtg accggcttgt cacattggag      780

tcctgggcta atgatcctga ttatctgaaa cgtcaagttg gtttctgtgc ccagtggagc      840

ttagacaatc tctttttaaa agaaggtaga cagctgacct atgagaaagt gaacttgagt      900

agcattaggg ccatgctgaa tagcaatgat gtcagcgagt acctgaagat ctcacctcat      960

ggcttagagg ctcgctgtga tgcctcctct tttgaaagtg tgcgttgcac cttttgtgtg     1020

gatgccgggg tatggtacta tgaagtaaca gtggtcactt ctggcgtcat gcagattggc     1080

tgggccactc gagacagcaa attcctcaat catgaaggct acggcattgg ggatgatgaa     1140

tactcctgtg cgtatgatgg ctgccggcag ctgatttggt acaatgccag aagtaagcct     1200

cacatacacc catgctggaa agaaggagat acagtaggat ttctgttaga cttgaatgaa     1260

aagcaaatga tcttcttttt aaatggcaac cagctgcctc ctgaaaagca agtcttttca     1320

tctactgtat ctggattttt tgctgcagct agtttcatgt catatcaaca atgtgagttc     1380

aattttggag caaaaccatt caaataccca ccatctatga aatttagcac ttttaatgac     1440

tacgccttcc taacagctga agaaaaaatc attttgccaa ggcacaggcg tcttgctctg     1500

ttgaagcaag tcagtatccg agaaaactgc tgttcccttt gttgtgatga ggtagcagac     1560

acacaattga agccatgtgg acacagtgac ctgtgcatgg attgtgcctt gcagctggag     1620

acctgcccat tgtgtcgtaa agaaatagta tctagaatca gacagatttc tcatatttca     1680


<210>  5870
<211>  1350
<212>  DNA
<213>  Homo Sapiens

<400>  5870
cttcctcaac tcagcgatga catccctttc cgagtcaact ggcccggcac cgagttctct       60

ctgcccacaa ctggagtttt atataaagaa gataattatg tcatcatgac aactgcacat      120

aaagaaaaat ataaatgcat acttcccctt gtgacaagtg gggatgagga agaagaaaag      180

gattataaag gccctaatcc aagagagctt ttggagccac tatttaaaca aagcagttgt      240

tcctacagaa ttgagtctta ttggacttac gaagtatgtc atggaaaaca cattcggcag      300

taccatgaag agaaagaaac tggtcagaaa ataaatattc acgagtacta ccttgggaat      360

atgttggcca agaaccttct atttgaaaaa gaacgagaag cagaagaaaa ggaaaaatca      420

aatgagattc ccactaaaaa tatcgaaggt cagatgacac catactatcc tgtgggaatg      480

ggaaatggta caccttgtag tttgaaacag aaccggccca gatcaagtac tgtgatgtac      540

atatgtcatc ctgaatctaa gcatgaaatt ctttcagtag ctgaagttac aacttgtgaa      600

tatgaagttg tcattttgac accactcttg tgcagtcatc ctaaatatag gttcagagca      660

tctcctgtga atgacatatt ttgtcaatca ctgccaggat ctccatttaa gcccctcacc      720

ctgaggcagc tggagcagca ggaagaaata ctaagggtgc cttttaggag aaataaagag      780

gaagatttgc aatcaactaa agaagagaga tttccagcga tccacaagtc gattgctatt      840

ggctctcagc cagtgctcac tgttgggaca acccacatat ccaaattgac agatgaccaa      900

ctcataaaag agtttcttag tggttcttac tgctttcgtg ggggtgtcgg ttggtggaaa      960

tatgaattct gctatggcaa acatgtacat caataccatg aggacaagga tagtgggaaa     1020

acctctgtgg ttgtcgggac atggaaccaa gaagagcata ttgaatgggc taagaagaat     1080

actgctagag cttatcatct tcaagacgat ggtacccaga cagtcaggat ggtgtcacat     1140

ttttatggaa atggagatat ttgtgatata actgacaaac caagacaggt gactgtaaaa     1200

ctaaagtgca aagaatcaga ttcacctcat gctgttactg tatatatgct agagcctcac     1260

tcctgtcaat atattcttgg ggttgaatct ccagtgatct gtaaaatctt agatacagca     1320

gatgaaaatg gacttctttc tctccccaac                                      1350


<210>  5871
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  5871
ttgatgttac tgcactatac ttttcaacaa ccaagacatc aaagcagtgt caagttacgt       60

gagcaaatac tagacttaag caaaagatat gttaaagctc tagcagagga aaataagaac      120

acagtggatg tcgagaacgg tgcttctatg gcaggatatg cggatctgaa aagaacaatt      180

gctgtccttc tggatgacat tttgcaacga ttggtgaagc tggagaacaa agttgactat      240

attgttgtga atggctcagc agccaacacc accaatggta ctagtgggaa tttggtgcca      300

gtaaccacaa ataaaagaac gaatgtctcg ggcagtatca ga                         342


<210>  5872
<211>  1527
<212>  DNA
<213>  Homo Sapiens

<400>  5872
ggatttcttt atcctcttgt ggatttttgc atcagtggga aaacaagagg acagaagcca       60

aactttgtga ttattttggc cgatgacatg gggtggggtg acctgggagc aaactgggca      120

gaaacaaagg acactgccaa ccttgataag atggcttcgg agggaatgag gtttgtggat      180

ttccatgcag ctgcctccac ctgctcaccc tcccgggctt ccttgctcac cggccggctt      240

ggccttcgca atggagtcac acgcaacttt gcagtcactt ctgtgggagg ccttccgctc      300

aacgagacca ccttggcaga ggtgctgcag caggcgggtt acgtcactgg gataataggc      360

aaatggcatc ttggacacca cggctcttat caccccaact tccgtggttt tgattactac      420

tttggaatcc catatagcca tgatatgggc tgtactgata ctccaggcta caaccaccct      480

ccttgtccag cgtgtccaca gggtgatgga ccatcaagga accttcaaag agactgttac      540

actgacgtgg ccctccctct ttatgaaaac ctcaacattg tggagcagcc ggtgaacttg      600

agcagccttg cccagaagta tgctgagaaa gcaacccagt tcatccagcg tgcaagcacc      660

agcgggaggc ccttcctgct ctatgtggct ctggcccaca tgcacgtgcc cttacctgtg      720

actcagctac cagcagcgcc acggggcaga agcctgtatg gtgcagggct ctgggagatg      780

gacagtctgg tgggccagat caaggacaaa gttgaccaca cagtgaagga aaacacattc      840

ctctggttta caggagacaa tggcccgtgg gctcagaagt gtgagctagc gggcagtgtg      900

ggtcccttca ctggattttg gcaaactcgt caagggggaa gtccagccaa gcagacgacc      960

tgggaaggag ggcaccgggt cccagcactg gcttactggc ctggcagagt tccagttaat     1020

gtcaccagca ctgccttgtt aagcgtgctg gacatttttc caactgtggt agccctggcc     1080

caggccagct tacctcaagg acggcgcttt gatggtgtgg acgtctccga ggtgctcttt     1140

ggccggtcac agcctgggca cagggtgctg ttccacccca acagcggggc agctggagag     1200

tttggagccc tgcagactgt ccgcctggag cgttacaagg ccttctacat taccggtgga     1260

gccagggcgt gtgatgggag cacggggcct gagctgcagc ataagtttcc tctgattttc     1320

aacctggaag acgataccgc agaagctgtg cccctagaaa gaggtggtgc ggagtaccag     1380

gctgtgctgc ccgaggtcag aaaggttctt gcagacgtcc tccaagacat tgccaacgac     1440

aacatctcca gcgcagatta cactcaggac ccttcagtaa ctccctgctg taatccctac     1500

caaattgcct gccgctgtca agccgca                                         1527


<210>  5873
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5873
atggacggca acgacaacgt gaccctgctc ttcgcccctc tgctgcggga caactacacc       60

ctggcgccca atgccagcag cctgggcccc ggcacggacc tcgccctcgc ccctgcctcc      120

agcgccggcc ccggccctgg gctcagcctc gggccgggtc cgagcttcgg cttcagcccc      180

ggccccactc cgaccccgga gcccacgacc agcggcctcg cgggcggcgc ggcgagccac      240

ggcccttccc cgttccctcg gccctgggcg ccccacgcgc tcccgttctg ggacacgccg      300

ctgaaccac                                                              309


<210>  5874
<211>  1287
<212>  DNA
<213>  Homo Sapiens

<400>  5874
gcatccaacg atccacgcaa ctttgtccct aacaaaatgt ggaagggatt agtcaagagg       60

aatgcatctg tggaaacagt tgataataaa acgtctgagg atgtaaccat ggcagcagct      120

tctcctgtca cattgaccaa agggacttcg gcagcccacc tcaactctat ggaagtcaca      180

acagaggaca caagcaggac agatgtgagt gaaccagcaa cttcaggagt tgcagctgat      240

ggtgtgacct ccattgctcc cacggctgtg gcctccagta cgactgcggc ctccattacg      300

actgcggcct ccagtatgac tgtggcctcc agtgctccca cgactgcagc ctccagtaca      360

actgtggcct ccattgctcc cacgactgca gcctccagta tgactgcggc ctccagcact      420

cccatgacac ttgcactccc cgcgcccacg tccacttcca cagggcggac cccgtccact      480

accgccactg ggcatccatc tctcagcaca gccctcgcac aagtgccaaa gagcagcgcg      540

ttgccaagaa cagcaaccct ggccacattg gccacacgtg ctcagactgt agcgaccaca      600

gcaaacacaa gcagccccat gagcactcgt ccaagtcctt ccaagcacat gcccagtgac      660

accgcggcaa gccctgtacc ccctatgcgt ccccaagcac aaggtcccat tagccaggtg      720

tcagtggacc agcctgtggt taacacaaca aataaatcca cacccatgcc ctcaaacaca      780

accccagagc ccgcccccac ccccacagtg gtgaccacca ccaaggcaca agccagggag      840

ccaactgcca gcccagtgcc agtacctcac accagcccaa tccctgagat ggaggccatg      900

tcccccacga cacagccaag ccccatgcca tatacccaga gggccgctgg gccaggcaca      960

tcccaggcac cggagcaggt agagactgaa gccacaccag gtactgattc cactgggcca     1020

acacccagga gctcaggggg cactaagatg ccagccacgg actcgtgcca gcccagcacc     1080

caaggccagt acatggtggt caccactgag cccctcaccc aggccgtggt agacaaaact     1140

ctccttctgg tggtgctgtt actcggggtg acccttttca tcacagtctt ggttttgttt     1200

gccctgcagg cctatgagag ctacaagaag aaggactaca cccaggtgga ctacttaatc     1260

aacgggatgt atgcggactc agaaatg                                         1287


<210>  5875
<211>  990
<212>  DNA
<213>  Homo Sapiens

<400>  5875
cggggctacc tgacccggcc tcacctggtg gcaatggacc ccgctgcccc agccccagtg       60

gcgggcttcc cggctgtcac cctctgcaat atcaaccgct tccggcattc ggcactcagc      120

gatgccgaca tcttccacct ggccaatctg acagggctgc cccccaaaga ccgggatggg      180

caccgtgcgg ctggcctgcg ctacccagag cctgacatgg tagacatcct caaccgcact      240

ggccaccagc tcgccgacat gcttaagagc tgcaacttca gtgggcatca ctgctccgcc      300

agcaacttct ctgtggtcta tactcgctat gggaagtgtt acaccttcaa cgcggacccg      360

cggagctcgc tgcccagccg ggcagggggc atgggcagtg gcctggagat catgctggac      420

atccagcagg aggagtacct gcccatctgg agggagacaa atgagacgtc gtttgaggca      480

ggtattcggg tgcagatcca cagccaggag gagccgccct acatccacca gctggggttc      540

ggggtgtccc caggcttcca gacctttgtg tcctgccagg aacagcggct gacctacctg      600

ccccagccct ggggcaactg ccgcgcagag agtgagctca gggagcctga gcttcagggc      660

tactcggcct acagtgtgtc tgcctgccgg ctgcgctgtg aaaaggaggc cgtgcttcag      720

cgctgccact gccggatggt gcacatgcca gactccctgg gtgggggccc tgagggcccg      780

tgcttctgcc ccaccccctg caacctgaca cgctatggga aagagatctc catggtcagg      840

atccccaaca ggggctcagc ccggtacctg gcgaggaagt acaaccgcaa cgagacctac      900

atacgggaga acttcctggt cctagatgtc ttctttgagg ccctgacctc tgaagccatg      960

gagcagcgag cagcctatgg cctgtcagcc                                       990


<210>  5876
<211>  360
<212>  DNA
<213>  Homo Sapiens

<400>  5876
ctgcacacct ttctgcttta tctgggtcca catatagcct cagttacatt agctgcttat       60

gaatgcaatt cagttaattt tcccgaacca ccctatcctg atcagattat ttgtccagat      120

gaagagggca ctgaaggaac catttttttg tggagtatca tctcaaaagt taggattgaa      180

gcctgcatgt ggggtatcgg tacagcaatc ggagagctgc ctccatattt catggccaga      240

gcagctcgcc tctcaggtgc tgaaccagat gatgaagagt atcaggaatt tgaagagatg      300

ctggaacatg cagagtctgc acaagacttt gcctcccggg ccaaactggc agttcaaaaa      360


<210>  5877
<211>  1929
<212>  DNA
<213>  Homo Sapiens

<400>  5877
gacctggctt tcatccctcc ttttatccga atgtccggcc ctgcggtcag cgcgtccctg       60

gtcggagaca ccgagggtgt gaccgtgtcc ctggcagtgc tgcaggacga ggcgggaata      120

ttgccaattc cgacgtgtgg agtgctgaac aatgagacgg aagactggag cgtgactgtg      180

atccccggtg cgaaggtgtt ggaagtgaca gtgaggtgga agagaggtct ggactggtgt      240

tcctccaatg agacagattc cttctcagag tccccctgta tcctccagac ccttctggtt      300

tcagcatctc ataattcatc ctgttcagca catctactca ttcaagtgga aatttatgcc      360

aactcttctc tgacccataa tgcctcagag aacgtgactg tcattcctaa ccaggtgtat      420

cagccccttg gcccttgtcc ttgtaattta acagctggag cctgtgatgt tcgctgctgc      480

tgtgaccagg aatgctcatc aaatttaaca acgctgttca gacggtcctg cttcaccggc      540

gtgtttggag gagacgtcaa tcctcctttt gatcagctct gctctgctgg gacgacgaca      600

cgtggtgtcc ccgattggtt tccctttctg tgtgtgcagt ccccccttgc caacacaccc      660

ttccttggtt acttctatca tggtgctgtt tcccccaaac aggactcttc ctttgaagta      720

tatgtggata ctgacgcaaa agactttgca gactttggtt acaaacaagg agatcccatt      780

atgactgtaa agaaggcata ttttactatt ccgcaggtgt ccctggctgg gcagtgtatg      840

cagaacgccc cagtggcatt tcttcacaat tttgatgtta aatgcgttac taatttggaa      900

ctataccaag aacgagatgg tattatcaat gcgaagataa agaatgttgc cttaggaggc      960

atagttacac caaaagtgat ctatgaggaa gcaactgacc tagacaaatt catcaccaat     1020

acagaaactc ctttaaataa cggatcaacc cctagaattg tgaatgtgga agaacattat     1080

attttcaaat ggaataataa taccatcagt gaaataaatg ttaaaatttt tagggcagag     1140

attaatgccc accagaaagg gataatgaca cagagatttg tagtaaaatt tttaagctat     1200

aatagtggta atgaagaaga attatctgga aatccaggtt accaacttgg caagcctgtc     1260

cgagctctaa atatcaacag gatgaataat gtcacgactt tacatctttg gcaatcggct     1320

ggaaggggtc tgtgtacatc agcaactttc aaacccattt tatttggaga aaatgtactc     1380

tctggatgcc tgttagaagt cgggattaat gaaaattgta ctcagctcag ggagaatgct     1440

gttgaaagac ttgattcatt aatacaagcg actcacgttg caatgagagg caactccgat     1500

tacgctgatc ttagtgatgg ctggctcgaa ataatacgtg tagatgcccc tgatccaggt     1560

gcagacccgc tggctagcag tgtgaacggc atgtgcctgg atattcctgc tcacctgagc     1620

atccgcatcc tcatctcgga tgctggcgcg gtggaaggga ttactcagca ggagatactc     1680

ggtgtagaga caaggttctc ctcagtgaac tggcagtacc agtgtgggct tacctgtgag     1740

cacaaggccg accttctccc tatcagtgca tccgtccagt ttattaaaat tcctgcacag     1800

ttaccccacc ccctgacaag attccagatc aattatacag agtatgactg caacagaaat     1860

gaggtgtgtt ggccgcagct tctatatcca tggactcagt attatcaagg ggagctgcat     1920

tctcagtgt                                                             1929


<210>  5878
<211>  1335
<212>  DNA
<213>  Homo Sapiens

<400>  5878
gaggagcagc ccccggagac agcggcacag aggtgcttct gccaggttag tggttacttg       60

gatgattgta cctgtgatgt tgaaaccatt gatagattta ataactacag gcttttccca      120

agactacaaa aacttcttga aagtgactac tttaggtatt acaaggtaaa cctgaagagg      180

ccgtgtcctt tctggaatga catcagccag tgtggaagaa gggactgtgc tgtcaaacca      240

tgtcaatctg atgaagttcc tgatggaatt aaatctgcga gctacaagta ttctgaagaa      300

gccaataatc tcattgaaga atgtgaacaa gctgaacgac ttggagcagt ggatgaatct      360

ctgagtgagg aaacacagaa ggctgttctt cagtggacca agcatgatga ttcttcagat      420

aacttctgtg aagctgatga cattcagtcc cctgaagctg aatatgtaga tttgcttctt      480

aatcctgagc gctacactgg ttacaaggga ccagatgctt ggaaaatatg gaatgtcatc      540

tacgaagaaa actgttttaa gccacagaca attaaaagac ctttaaatcc tttggcttct      600

ggtcaaggga caagtgaaga gaacactttt tacagttggc tagaaggtct ctgtgtagaa      660

aaaagagcat tctacagact tatatctggc ctacatgcaa gcattaatgt gcatttgagt      720

gcaagatatc ttttacaaga gacctggtta gaaaagaaat ggggacacaa cattacagaa      780

tttcaacagc gatttgatgg aattttgact gaaggagaag gtccaagaag gcttaagaac      840

ttgtattttc tctacttaat agaactaagg gctttatcca aagtgttacc attcttcgag      900

cgcccagatt ttcaactctt tactggaaat aaaattcagg atgaggaaaa caaaatgtta      960

cttctggaaa tacttcatga aatcaagtca tttcctttgc attttgatga gaattcattt     1020

tttgctgggg ataaaaaaga agcacacaaa ctaaaggagg actttcgact gcattttaga     1080

aatatttcaa gaattatgga ttgtgttggt tgttttaaat gtcgtctgtg gggaaagctt     1140

cagactcagg gtttgggcac tgctctgaag atcttatttt ctgagaaatt gatagcaaat     1200

atgccagaaa gtggacctag ttatgaattc catctaacca gacaagaaat agtatcatta     1260

ttcaacgcat ttggaagaat ttctacaagt gtgaaagaat tagaaaactt caggaacttg     1320

ttacagaata ttcat                                                      1335


<210>  5879
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  5879
ctcttcctct ttggccagcc cgacttctcc tacaagcgca gcaattgcaa gcccatcccg       60

gtcaacctgc agctgtgcca cggcatcgaa taccagaaca tgcggctgcc caacctgctg      120

ggccacgaga ccatgaagga ggtgctggag caggccggcg cttggatccc gctggtcatg      180

aagcagtgcc acccggacac caagaagttc ctgtgctcgc tcttcgcccc cgtctgcctc      240

gatgacctag acgagaccat ccagccatgc cactcgctct gcgtgcaggt gaaggaccgc      300

tgcgccccgg tcatgtccgc cttcggcttc ccctggcccg acatgcttga gtgcgaccgt      360

ttcccccagg acaacgacct ttgcatcccc ctcgctagca gcgaccacct cctgccagcc      420

accgaggaag ctccaaaggt atgtgaagcc tgcaaaaata aaaatgatga tgacaacgac      480

ataatggaaa cgctttgtaa aaatgatttt gcactgaaaa taaaagtgaa ggagataacc      540

tacatcaacc gagataccaa aatcatcctg gagaccaaga gcaagaccat ttacaagctg      600

aacggtgtgt ccgaaaggga cctgaagaaa tcggtgctgt ggctcaaaga cagcttgcag      660

tgcacctgtg aggagatgaa cgacatcaac gcgccctatc tggtcatggg acagaaacag      720

ggtggggagc tggtgatcac ctcggtgaag cggtggcaga aggggcagag agagttcaag      780

cgcatctccc gcagcatccg caagctgcag tgc                                   813


<210>  5880
<211>  477
<212>  DNA
<213>  Homo Sapiens

<400>  5880
atggaagagc caacagcagt agaaggccag gtccagcttc caagccccca ccagggctct       60

ctcaggaagg ctgtggctgc tgccctggcg ctggatgggg aatccacaat ggggcacagg      120

aaaaagaaga ggaaagagtc acgcccagaa tccatcatca tctaccgctc agacaatgag      180

aaaacagatg aggagcccgg agaatcagaa ggtggagatc agcctaaaga ggaggaggga      240

gatgatttcc tagactatcc tgtggatgat gatatgtgga acctgcctct ggacagccgc      300

tacgtcacct taactgggac catcacacga gggaagaaaa agggtcagat ggtggacatc      360

catgtcacat tgacagagaa agagctgcag gaactgacca aacctaaaga gtcatcaagg      420

gaaacgacgc ctgaaggaag aatggcctgc cagatgggag ctgaccgtgg gccccat         477


<210>  5881
<211>  885
<212>  DNA
<213>  Homo Sapiens

<400>  5881
gccatccgta ttgaggctgc gtcactgaga ttgacactca gcactttgcg ccaccttact       60

ctaaccagca taatgaaatc caaaaggaaa actgatcaca tggagagaac tgcaagtgtc      120

cttcgacggg agattgtgtc agcagctaag gtgtgtggag ctgccagtga gtcaccgtca      180

gtgaagagcc tccgcttgct tgttgctgat caagactttt cctttaaagc tggccagtgg      240

gttgatttct ttattccagg agtctctgtg gttggtgggt tttcaatatg ctccagtccc      300

agactgctag aacaagagag agtgatagaa ttggcagtga aatatacgaa ccaccctcct      360

gccctctggg ttcacaatac gtgtacactt gactgtgaag tggctgtgag agtgggtgga      420

gagttcttct ttgaccctca gcctgcggat gcctctagaa acctcgtgtt gattgcagga      480

ggagtcggaa ttaaccctct gctttccatc ctgcggcacg cagcagatct cctcagagag      540

caggcaaaca aaagaaatgg atatgagata ggaacaataa aactattcta cagtgcaaaa      600

aataccagcg aactcctgtt taagaaaaat atccttgatt tagtaaatga atttcctgag      660

aagattgcat gcagtttgca tgttacaaaa cagactacac aaatcaatgc ggaactcaag      720

ccatacatca cggaaggaag aataacggag aaggagataa gagatcatat ttcaaaagag      780

actttgttct atatttgtgg cccacctcca atgacagact ttttctccaa gcaactggaa      840

aacaaccatg tacccaaaga acacatttgc tttgagaagt ggtgg                      885


<210>  5882
<211>  147
<212>  DNA
<213>  Homo Sapiens

<400>  5882
ttgtacttgc tgtcgacgcg actgccccgc gggcggagac tgggctccac cgaggaggct       60

ggaggcaggt cgctgtggtt cccctccgac ctggcagagc tgcgggagct ctctgaggtc      120

cttcgagagt accggaagga gcaccag                                          147


<210>  5883
<211>  858
<212>  DNA
<213>  Homo Sapiens

<400>  5883
gcatcagccg gccaagagcc actgcacaat gaggagctgg caggagcagg ccgggtggcc       60

cagcctgggc ccctggagcc tgaggagccg agagctggag gcaggcctcg gcgccggagg      120

gacctgggca gccgcctaca ggcccagcgt cgagcccagc gggtggcctg ggcagaagca      180

gatgagaacg aggaggaagc tgtcatccta gcccaggagg aggaaggtgt cgagaagcca      240

gcggaaactc acctgtcggg gaaaattgga gctaagaaac tgcggaagct ggaggagaaa      300

caagcgcgaa aggcccagcg tgaggcagag gaggctgaac gtgaggagcg gaaacgactc      360

gagtcccagc gcgaagctga gtggaagaag gaggaggagc ggcttcgcct ggaggaggag      420

cagaaggagg aggaggagag gaaggcccgc gaggagcagg cccagcggga gcatgaggag      480

tacctgaaac tgaaggaggc ctttgtggtg gaggaggaag gcgtaggaga gaccatgact      540

gaggaacagt cccagagctt cctgacagag ttcatcaact acatcaagca gtccaaggtt      600

gtgctcttgg aagacctggc ttcccaggtg ggcctacgca ctcaggacac cataaatcgc      660

atccaggacc tgctggctga ggggactata acaggtgtga ttgacgaccg gggcaagttc      720

atctacataa ccccagagga actggccgcc gtggccaact tcatccgaca gcggggccgg      780

gtgtccatcg ccgagcttgc ccaagccagc aactccctca tcgcctgggg ccgggagtcc      840

cctgcccaag ccccagcc                                                    858


<210>  5884
<211>  927
<212>  DNA
<213>  Homo Sapiens

<400>  5884
gcctccgcat cgtactatga acagtatcac tcactaaatg aaatctattc ttggatagaa       60

tttataactg agaggcatcc tgatatgctt acaaaaatcc acattggatc ctcatttgag      120

aagtacccac tctatgtttt aaaggtttct ggaaaagaac aagcagccaa aaatgccata      180

tggattgact gtggaatcca tgccagagaa tggatctctc ctgctttctg cttgtggttc      240

ataggccata taactcaatt ctatgggata atagggcaat ataccaatct cctgaggctt      300

gtggatttct atgttatgcc ggtggttaat gtggatggtt atgactactc atggaaaaag      360

aatcgaatgt ggagaaagaa ccgttctttc tatgcgaaca atcattgcat cggaacagac      420

ctgaatagga actttgcttc caaacactgg tgtgaggaag gtgcatccag ttcctcatgc      480

tcggaaacct actgtggact ttatcctgag tcagaaccag aagtgaaggc agtggctagt      540

ttcttgagaa gaaatatcaa ccagattaaa gcatacatca gcatgcattc atactcccag      600

catatagtgt ttccatattc ctatacacga agtaaaagca aagaccatga ggaactgtct      660

ctagtagcca gtgaagcagt tcgtgctatt gagaaaacta gtaaaaatac caggtataca      720

catggccatg gctcagaaac cttataccta gctcctggag gtggggacga ttggatctat      780

gatttgggca tcaaatattc gtttacaatt gaacttcgag atacgggcac atacggattc      840

ttgctgccgg agcgttacat caaacccacc tgtagagaag cttttgccgc tgtctctaaa      900

atagcttggc atgtcattag gaatgtt                                          927


<210>  5885
<211>  867
<212>  DNA
<213>  Homo Sapiens

<400>  5885
gtggaggttg cagaggaaag tggtcgctta tggtcagagg agcagcctgc tcaccctctc       60

caggttgggg ctgtgtacct gggtgaggag gagctcctgc atgacccgat gggccaggac      120

agggcagcag aagaggccaa tgcggtgctg gggctggaca cccaaggcga tcacatggtg      180

atgctgtctg tgattcctgg ggaagctgag gacaaagtga gttcagagcc tagcggcgtc      240

acctgtggtg ctggaggagc ggaggactca aggtgcaacg tccgagagag ccttttctct      300

ctggatggcg ctggagcaca cttccctgac agagaagagg agtattacac agagccagaa      360

gtggcggaat ctgacgcagc cccgacagag gactccaata acactgaaag tctgaaatcc      420

ccaaaggtga actgtgagga gagaaacatt acaggattag aaaatttcac tctgaaaatt      480

ttaaatatgt cacaggacct tatggatttt ctgaacccaa acggtagtga ctgtactcta      540

gtcctgtttt acaccccgtg gtgccgcttt tctgccagtt tggcccctca ctttaactct      600

ctgccccggg catttccagc tcttcacttt ttggcactgg atgcatctca gcacagcagc      660

ctttctacca ggtttggcac cgtagctgtt cctaatattt tattatttca aggagctaaa      720

ccaatggcca gatttaatca tacagatcga acactggaaa cactgaaaat cttcattttt      780

aatcagacag gtatagaagc caagaagaat gtggtggtaa ctcaagccga ccaaataggc      840

cctcttccca gcactttgat aaaaagt                                          867


<210>  5886
<211>  2196
<212>  DNA
<213>  Homo Sapiens

<400>  5886
cagtcactgg gcaccactaa gctccggctg gtgggcccag agagcaagcc agaggagggc       60

cgcctggagg tgctgcacca gggccagtgg ggcaccgtgt gtgatgacaa ctttgctatc      120

caggaggcca cagtggcttg ccgccagctg ggcttcgaag ctgccttgac ctgggcccac      180

agtgccaagt acggccaagg ggagggaccc atctggctgg acaatgtgcg ctgtgtgggc      240

acagagagct ccttggacca gtgcgggtct aatggctggg gagtcagtga ctgcagtcac      300

tcagaagacg taggggtgat atgccacccc cggcgccatc gtggctacct ttctgaaact      360

gtctccaatg cccttgggcc ccagggccgg cggctggagg aggtgcggct caagcccatc      420

cttgccagtg ccaagcagca tagcccagtg accgagggag ccgtggaggt gaagtatgag      480

ggccactggc ggcaggtgtg tgaccagggc tggaccatga acaacagcag ggtggtgtgc      540

gggatgctgg gcttccccag cgaggtgcct gtcgacagcc actactacag gaaagtctgg      600

gatctgaaga tgagggaccc taagtctagg ctgaagagcc tgacgaataa gaactccttc      660

tggatccacc aggtcacctg cctggggaca gagccccaca tggccaactg ccaggtgcag      720

gtggctccag cccggggcaa gctgcggcca gcctgcccag gtggcatgca tgctgtggtc      780

agctgtgtgg cagggcctca cttccgccca ccgaagacaa agccacaacg caaagggtcc      840

tgggcagagg agccgagggt gcgcctgcgc tccggggccc aggtgggcga gggccgggtg      900

gaagtgctca tgaaccgcca gtggggcacg gtctgtgacc acaggtggaa cctcatctct      960

gccagtgtcg tgtgtcgtca gctgggcttt ggctctgctc gggaggccct ctttggggcc     1020

cggctgggcc aagggctagg gcccatccac ctgagtgagg tgcgctgcag gggatatgag     1080

cggaccctca gcgactgccc tgccctggaa gggtcccaga atggttgcca acatgagaat     1140

gctgctgctg tcaggtgcaa tgtccctaac atgggctttc agaatcaggt gcgcttggct     1200

ggtgggcgta tccctgagga ggggctattg gaggtgcagg tggaggtgaa cggggtccca     1260

cgctggggga gcgtgtgcag tgaaaactgg gggctcaccg aagccatggt ggcctgccga     1320

cagctcggcc tgggttttgc catccatgcc tacaaggaaa cctggttctg gtcggggacg     1380

ccaagggccc aggaggtggt gatgagtggg gtgcgctgct caggcacaga gctggccctg     1440

cagcagtgcc agaggcacgg gccggtgcac tgctcccacg gtggcgggcg cttcctggct     1500

ggagtctcct gcatggacag tgcaccagac ctggtgatga acgcccagct agtgcaggag     1560

acggcctact tggaggaccg cccgctcagc cagctgtatt gtgcccacga ggagaactgc     1620

ctctccaagt ctgcggatca catggactgg ccctacggat accgccgcct attgcgcttc     1680

tccacacaga tctacaatct gggccggact gactttcgtc caaagactgg acgcgatagc     1740

tgggtttggc accagtgcca caggcattac cacagcattg aggtcttcac ccactacgac     1800

ctcctcactc tcaatggctc caaggtggct gaggggcaca aggccagctt ctgtctggag     1860

gacacaaact gccccacagg actgcagcgg cgctacgcat gtgccaactt tggagaacag     1920

ggagtgactg taggctgctg ggacacctac cggcatgaca ttgattgcca gtgggtggat     1980

atcacagatg tgggccccgg gaattatatc ttccaggtga ttgtgaaccc ccactatgaa     2040

gtggcagagt cagatttctc caacaatatg ctgcagtgcc gctgcaagta tgatgggcac     2100

cgggtctggc tgcacaactg ccacacaggg aattcatacc cagccaatgc agaactctcc     2160

ctggagcagg aacagcgtct caggaacaac ctcatc                               2196


<210>  5887
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  5887
atgactaata gtaaaggaag atctattacc gataaaacaa gtggtggtcc aagtagtgga       60

ggaggttttg tagattggac tttacgttta aacacaattc aatccgacaa gtttttaaat      120

ttactcttga gtatggttcc agtgatttac cagaaaaacc aagaagacag gcacaaaaaa      180

gcaaacggca tttggcaaga tggattatca actgcagtac agacttttag taatagatct      240

gagcaacaca tggagtatca cagtttctca gagcagtctt ttcatgccaa taatgggcac      300

gcatcatcaa gctgcagcca aaagtatgat gactatgcca attataatta ctgtgatgga      360

agggagactt cagaaaccac tgccatgtta caagatgaag atatatctag tgatggtgat      420

gaagatgcta ttgtagaagt gaccccaaaa ttaccaaagg aatccagtgg catcatggca      480

ttgcaa                                                                 486


<210>  5888
<211>  1236
<212>  DNA
<213>  Homo Sapiens

<400>  5888
ctgggcatct ggaggattgt gatcaggatc caaagaggaa aatctacttc ctcatcaagc       60

acccctacag agttctgcag gaatggtgga acctgggaaa atggcagatg tatttgtaca      120

gaagagtgga aaggactgag atgtacaatt gctaattttt gtgaaaatag tacctatatg      180

ggttttactt ttgccagaat cccagtgggc agatatggac catccttgca aacatgtggc      240

aaggatactc caaatgcggg caatccaatg gcagtccggt tgtgcagtct ctctctatat      300

ggagagatag aattacaaaa agtgacaata ggaaattgca atgaaaatct ggaaaccctg      360

gaaaagcagg taaaggatgt cacagcacca cttaataaca tttcttctga agtccagatt      420

ttaacatctg atgccaataa attaactgct gagaacatca ctagtgctac gcgagtggtt      480

ggacagatat tcaacacttc cagaaatgct tcacctgagg caaagaaagt tgccatagta      540

acagtgagtc aactcctaga tgccagtgaa gatgcttttc aaagagttgc tgctactgct      600

aatgatgatg cccttacaac gcttattgag caaatggaga cttattcctt gtctttgggt      660

aatcaatcag tggtggaacc taacatagca atacagtcag caaatttctc ttcagaaaat      720

gcggtggggc cttcaaatgt tcgcttctct gtgcagaaag gagctagcag ttctctagtt      780

tctagttcaa catttataca tacaaatgtg gatggcctta acccagatgc acagactgag      840

cttcaggtct tgcttaatat gacgaaaaat tacaccaaga catgcggctt tgtagtttat      900

caaaatgaca agcttttcca atcaaaaact tttacagcta aatcggattt tagtcaaaaa      960

attatctcaa gcaaaactga tgaaaatgag caagatcaga gtgcttctgt tgacatggtc     1020

tttagtccaa agtacaacca aaaagaattt caactctatt cctatgcctg tgtctattgg     1080

aatttgtcag cgaaggactg ggacacatat ggctgtcaaa aagacaaggg cactgatgga     1140

ttcctgcgct gccgctgcaa ccatactact aattttgctg tattaatgac tttcaaaaag     1200

gattatcaat atcccaaatc acttgacata ttatcc                               1236


<210>  5889
<211>  759
<212>  DNA
<213>  Homo Sapiens

<400>  5889
tacacccgcc cgtgctccgg cgacgccaac tgcatccagc cctacctggc gcggcggccc       60

aagctgcagc tgagcgtgta caccacgacg aggtcccacc tgggtgctga gaacaacatc      120

gacctggtct tgaatgtgga agactttgat gtggagtcca aatttgaaag gacagttaat      180

gtttctgtac caaagaaaac gagaaacaat gggacgctgt atgcctacat cttcctccat      240

cacgctgggg tcctgccgtg gcacgacggg aagcaggtgc acctggtcag tcctctgacc      300

acctacatgg tccccaagcc agaagaaatc aacctgctca ccggggagtc tgatacacag      360

cagatcgagg cggagaagaa gccgacgagt gccctggatg agccagtgtc ccactggcga      420

ccgcggctgg cgctgaacgt gatggcggac aactttgtct ttgacgggtc ctccctgcct      480

gccgatgtgc atcggtacat gaagatgatc cagctgggga aaaccgtgca ttacctgccc      540

atcctgttca tcgaccagct cagcaaccgc gtgaaggacc tgatggtcat aaaccgctcc      600

accaccgagc tgcccctcac cgtgtcctac gacaaggtct cactggggcg gctgcgcttc      660

tggatccaca tgcaggacgc cgtgtactcc ctgcagcagt tcgggttttc agagaaagat      720

gctgatgagg tgaaaggaat ttttgtagat accaactta                             759


<210>  5890
<211>  1443
<212>  DNA
<213>  Homo Sapiens

<400>  5890
tcaccctccc cgcccccggc gctgttagag aaagtcttcc agtacattga cctccatcag       60

gatgaatttg tgcagacgct gaaggagtgg gtggccatcg agagcgactc tgtccagcct      120

gtgcctcgct tcagacaaga gctcttcaga atgatggccg tggctgcgga cacgctgcag      180

cgcctggggg cccgtgtggc ctcggtggac atgggtcctc agcagctgcc cgatggtcag      240

agtcttccaa tacctcccgt catcctggcc gaactgggga gcgatcccac gaaaggcacc      300

gtgtgcttct acggccactt ggacgtgcag cctgctgacc ggggcgatgg gtggctcacg      360

gacccctatg tgctgacgga ggtagacggg aaactttatg gacgaggagc gaccgacaac      420

aaaggccctg tcttggcttg gatcaatgct gtgagcgcct tcagagccct ggagcaagat      480

cttcctgtga atatcaaatt catcattgag gggatggaag aggctggctc tgttgccctg      540

gaggaacttg tggaaaaaga aaaggaccga ttcttctctg gtgtggacta cattgtaatt      600

tcagataacc tgtggatcag ccaaaggaag ccagcaatca cttacggaac ccgggggaac      660

agctacttca tggtggaggt gaaatgcaga gaccaggatt ttcactcagg aacctttggt      720

ggcatccttc atgaaccaat ggctgatctg gttgctcttc tcggtagcct ggtagactcg      780

tctggtcata tcctggtccc tggaatctat gatgaagtgg ttcctcttac agaagaggaa      840

ataaatacat acaaagccat ccatctagac ctagaagaat accggaatag cagccgggtt      900

gagaaatttc tgttcgatac taaggaggag attctaatgc acctctggag gtacccatct      960

ctttctattc atgggatcga gggcgcgttt gatgagcctg gaactaaaac agtcatacct     1020

ggccgagtta taggaaaatt ttcaatccgt ctagtccctc acatgaatgt gtctgcggtg     1080

gaaaaacagg tgacacgaca tcttgaagat gtgttctcca aaagaaatag ttccaacaag     1140

atggttgttt ccatgactct aggactacac ccgtggattg caaatattga tgacacccag     1200

tatctcgcag caaaaagagc gatcagaaca gtgtttggaa cagaaccaga tatgatccgg     1260

gatggatcca ccattccaat tgccaaaatg ttccaggaga tcgtccacaa gagcgtggtg     1320

ctaattccgc tgggagctgt tgatgatgga gaacattcgc agaatgagaa aatcaacagg     1380

tggaactaca tagagggaac caaattattt gctgcctttt tcttagagat ggcccagctc     1440

cat                                                                   1443


<210>  5891
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5891
tacatcttgg ggcgttgcac agtggctaag aaactccacg atggaggcct ggattatttt       60

gagggctata gccttgagaa ctgggtgtgc ctggcctact tcgagagcaa gttcaacccc      120

atggccatct acgagaacac acgtgagggc tacactggct ttggcctctt tcagatgcgt      180

ggcagtgact ggtgtggcga ccatggcagg aaccgctgcc atatgtcatg ttccgcttta      240

ctgaatccta atttagagaa gacaattaaa tgtgccaaga ccattgtaaa aggaaaagaa      300

gggatgggag catggcccac ctggtcccgg tactgccagt actccgatac cctggcacgg      360

tggctggatg gttgcaagct g                                                381


<210>  5892
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  5892
atgcgctggg cggccgccac cctccgtggc aaggcgaggc cccgggggcg ggccggggtc       60

accacgcctg ccccagggaa ccgcacaggc acgtgcgcta agctgcggct acccccgcaa      120

gcaaccttcc aagtccttcg tggcaatggt gcttccgtgg ggaccgtgct catgttccgc      180

tgcccctcca accaccagat ggtggggtct gggctcctca cctgcacctg gaaggggagc      240

atcgctgagt ggtcttcagg gtccccagtg tgcaaactgg tgccaccaca cgagaccttt      300

ggcttcaag                                                              309


<210>  5893
<211>  1095
<212>  DNA
<213>  Homo Sapiens

<400>  5893
accgtctatt tccaagagga atttctagac ggagagcatt ggagaaaccg atggttgcag       60

tccaccaatg actcccgatt tgggcatttt agactttcgt cgggcaagtt ttatggtcat      120

aaagagaaag ataaaggtct gcaaaccact cagaatggcc gattctatgc catctctgca      180

cgcttcaaac cgttcagcaa taaagggaaa actctggtta ttcagtacac agtaaaacat      240

gagcagaaga tggactgtgg agggggctac attaaggtct ttcctgcaga cattgaccag      300

aagaacctga atggaaaatc gcaatactat attatgtttg gacccgatat ttgtggattt      360

gatatcaaga aagttcatgt tattttacat ttcaagaata agtatcacga aaacaagaaa      420

ctgatcaggt gtaaggttga tggcttcaca cacctgtaca ctctaatttt aagaccagat      480

ctttcttatg atgtgaaaat tgatggtcag tcaattgaat ccggcagcat agagtacgac      540

tggaacttaa catcactcaa gaaggaaacg tccccggcag aatcgaagga ttgggaacag      600

actaaagaca acaaagccca ggactgggag aagcattttc tggacgccag caccagcaag      660

cagagcgact ggaacggtga cctggatggg gactggccag cgccgatgct ccagaagccc      720

ccgtaccagg atggcctgaa accagaaggt attcataaag acgtctggct ccaccgtaag      780

atgaagaata ccgactattt gacgcagtat gacctctcag aatttgagaa cattggtgcc      840

attggcctgg agctttggca ggtgagatct ggaaccattt ttgataactt tctgatcaca      900

gatgatgaag agtatgcaga taattttggc aaggccacct ggggcgaaac caagggtcca      960

gaaagggaga tggatgccat acaggccaag gaggaaatga agaaggcccg cgaggaagag     1020

gaggaagagc tgctgtcggg aaaaattaac aggcacgaac attacttcaa tcaatttcac     1080

agaaggaatg aactt                                                      1095


<210>  5894
<211>  810
<212>  DNA
<213>  Homo Sapiens

<400>  5894
gttcccacca tcctgcccct gggcctggct ccagacacct ttgacgatac ctatgtgggt       60

tgtgtagagg agatggagga gaaggcagcc cccctgctaa aggaggaaat ggcccaccat      120

gccctgctgc gggaatcctg ggaggcagcc caggagacct gggaggacaa gcgtcgaggg      180

cttaccttgc cccctggctt caaagcccag aatggaatag ccattatggt ctacaccaac      240

tcatcgaaca ccttgtactg ggagttgaat caggccgtgc ggacgggcgg aggctcccgg      300

gagctctaca tgaggcactt tcccttcaag gccctgcatt tctacctgat ccgggccctg      360

cagctgctgc gaggcagtgg gggctgcagc aggggacctg gggaggtggt gttccgaggt      420

gtgggcagcc ttcgctttga acccaagagg ctgggggact ctgtccgctt gggccagttt      480

gcctccagct ccctggataa ggcagtggcc cacagatttg gtaatgccac cctcttctct      540

ctaacaactt gctttggggc ccctatacag gccttctctg tctttcccaa ggagcgcgag      600

gtgctgattc ccccccatga agtctttttg gttaccagat tctctcagga tggagcccag      660

agcttggtga ctctctggag ctataatcag acctgtagcc attttaactg cgcctatctg      720

ggtggggaga agaggcgggg ctgtgtgtct gcgccaggag ccctgggaac gggtgacctt      780

catatgacga agaggcacct ccagcagcct                                       810


<210>  5895
<211>  972
<212>  DNA
<213>  Homo Sapiens

<400>  5895
tgggatactc ccaccatcgt ctcccgcaag gagtgggggg caagaccgct cgcctgcagg       60

gccctgctga ccctgcctgt ggcctacatc atcacagacc agctcccagg gatgcagtgc      120

cagcagcaga gcgtttgcag ccagatgctg cgggggttgc agtcccattc cgtctacacc      180

ataggctggt gcgacgtggc gtacaacttc ctggttgggg atgatggcag ggtgtatgaa      240

ggtgttggct ggaacatcca aggcttgcac acccagggct acaacaacat ttccctgggc      300

atcgccttct ttggcaataa gataggcagc agtcccagcc ctgctgcctt atcagctgca      360

gagggtctga tctcctatgc catccagaag ggtcacctgt cgcccaggta tattcagcca      420

cttcttctga aagaagagac ctgcctggac cctcaacatc cagtgatgcc caggaaggtt      480

tgccccaaca tcatcaaacg atctgcttgg gaagccagag agacacactg ccctaaaatg      540

aacctcccag ccaaatatgt catcatcatc cacaccgctg gcacaagctg cactgtatcc      600

acagactgcc agactgtcgt ccgaaacata cagtcctttc acatggacac acggaacttt      660

tgtgacattg gatatcactt cctggtgggc caggatggtg gcgtgtatga aggggttgga      720

tggcacatcc aaggctctca cacttatgga ttcaacgata ttgccctagg aattgccttc      780

atcggctact ttgtagaaaa gcctccaaat gctgcagcgc tggaggcggc ccaggacctg      840

atccagtgtg ccgtggttga ggggtacctg actccaaact acctgctgat gggccacagt      900

gacgtggtca acatcctgtc ccctgggcag gctttgtata acatcatcag tacctggcct      960

catttcaagc ac                                                          972


<210>  5896
<211>  315
<212>  DNA
<213>  Homo Sapiens

<400>  5896
agccagcacc tccggggaca tgcaggtcac caccaaatca agcaagggac ctgtgaggtg       60

gtcgccgtgc acaggtgctg caataagaac cgcatagaag agcggtcaca aacggtcaag      120

tgctcttgct tcccgggaca ggtggcgggc acaactcggg ctcaaccttc ttgtgttgaa      180

gcttccattg tgattcagaa atggtggtgt cacatgaatc cgtgtttgga aggagaggat      240

tgtaaagtgc tgccagatta ctcaggttgg tcctgtagca gtggcaataa agtcaaaact      300

acgaaggtaa cgcgg                                                       315


<210>  5897
<211>  1443
<212>  DNA
<213>  Homo Sapiens

<400>  5897
atgtcgactc tttgcccacc gccatctcca gctgttgcca agacagagat tgctttaagt       60

ggcaaatcac ctttattagc agctactttt gcttactggg acaatattct tggtcctaga      120

gtaaggcaca tttgggctcc aaagacagaa caggtacttc tcagtgatgg agaaataact      180

tttcttgcca accacactct aaatggagaa atccttcgaa atgcagagag tggtgctata      240

gatgtaaagt tttttgtctt gtctgaaaag ggagtgatta ttgtttcatt aatctttgat      300

ggaaactgga atggggatcg cagcacatat ggactatcaa ttatacttcc acagacagaa      360

cttagtttct acctcccact tcatagagtg tgtgttgata gattaacaca tataatccgg      420

aaaggaagaa tatggatgca taaggaaaga caagaaaatg tccagaagat tatcttagaa      480

ggcacagaga gaatggaaga tcagggtcag agtattattc caatgcttac tggagaagtg      540

attcctgtaa tggaactgct ttcatctatg aaatcacaca gtgttcctga agaaatagat      600

atagctgata cagtactcaa tgatgatgat attggtgaca gctgtcatga aggctttctt      660

ctcaatgcca tcagctcaca cttgcaaacc tgtggctgtt ccgttgtagt aggtagcagt      720

gcagagaaag taaataagat agtcagaaca ttatgccttt ttctgactcc agcagagaga      780

aaatgctcca ggttatgtga agcagaatca tcatttaaat atgagtcagg gctctttgta      840

caaggcctgc taaaggattc aactggaagc tttgtgctgc ctttccggca agtcatgtat      900

gctccatatc ccaccacaca catagatgtg gatgtcaata ctgtgaagca gatgccaccc      960

tgtcatgaac atatttataa tcagcgtaga tacatgagat ccgagctgac agccttctgg     1020

agagccactt cagaagaaga catggctcag gatacgatca tctacactga cgaaagcttt     1080

actcctgatt tgaatatttt tcaagatgtc ttacacagag acactctagt gaaagccttc     1140

ctggatcagg tctttcagct gaaacctggc ttatctctca gaagtacttt ccttgcacag     1200

tttctacttg tccttcacag aaaagccttg acactaataa aatatataga agacgatacg     1260

cagaagggaa aaaagccctt taaatctctt cggaacctga agatagacct tgatttaaca     1320

gcagagggcg atcttaacat aataatggct ctggctgaga aaattaaacc aggcctacac     1380

tcttttatct ttggaagacc tttctacact agtgtgcaag aacgagatgt tctaatgact     1440

ttt                                                                   1443


<210>  5898
<211>  1524
<212>  DNA
<213>  Homo Sapiens

<400>  5898
cagctgcggc ctcgggagcg cccgcggggg tgcccgtgca ccggccgcgc ctcctccctg       60

gcgcgggact cggccgcagc tgcctcggac cccggcacga tcgtgcacaa cttttcccga      120

accgagcccc ggactgaacc ggctggcggc agccacagcg ggtcgagctc caagttgcag      180

gccctcttcg cccacccgct gtacaacgtc ccggaggagc cgcctctcct gggagccgag      240

gactcgctcc tggccagcca ggaggcgctg cggtattacc ggaggaaggt ggcccgctgg      300

aacaggcgac acaagatgta cagagagcag atgaacctta cctccctgga ccccccactg      360

cagctccgac tcgaggccag ctgggtccag ttccacctgg gtattaaccg ccatgggctc      420

tactcccggt ccagccctgt tgtcagcaaa cttctgcaag acatgaggca ctttcccacc      480

atcagtgctg attacagtca agatgagaaa gccttgctgg gggcatgtga ctgcacccag      540

attgtgaaac ccagtggggt ccacctcaag ctggtgctga ggttctcgga tttcgggaag      600

gccatgttca aacccatgag acagcagcga gatgaggaga caccagtgga cttcttctac      660

ttcattgact ttcagagaca caatgctgag atcgcagctt tccatctgga caggattctg      720

gacttccgac gggtgccgcc aacagtgggg aggatagtaa atgtcaccaa ggaaatccta      780

gaggtcacca agaatgaaat cctgcagagt gttttctttg tctctccagc gagcaacgtg      840

tgcttcttcg ccaagtgtcc atacatgtgc aagacggagt atgctgtctg tggcaaccca      900

cacctgctgg agggttccct ctctgccttc ctgccgtccc tcaacctggc ccccaggctg      960

tctgtgccca acccctggat ccgctcctac acactggcag gaaaagagga gtgggaggtc     1020

aatccccttt actgtgacac agtgaaacag atctacccgt acaacaacag ccagcggctc     1080

ctcaatgtca tcgacatggc catcttcgac ttcttgatag ggaatatgga ccggcaccat     1140

tatgagatgt tcaccaagtt cggggatgat gggttcctta ttcaccttga caacgccaga     1200

gggttcggac gacactccca tgatgaaatc tccatcctct cgcctctctc ccagtgctgc     1260

atgataaaaa agaaaacact tttgcacctg cagctgctgg cccaagctga ctacagactc     1320

agcgatgtga tgcgagaatc actgctggaa gaccagctca gccctgtcct cactgaaccc     1380

cacctccttg ccctggatcg aaggctccaa accatcctaa ggacagtgga ggggtgcata     1440

gtggcccatg gacagcagag tgtcatagtc gacggcccag tggaacagtc ggccccagac     1500

tctggccagg ctaacttgac aagc                                            1524


<210>  5899
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  5899
tctctgtctc caagccagcc gctgtcattc cagtgcctta aagctccagc cacactcacc       60

tgggaggatg agaagcagca gagatgggga cagccacatg gtcctgtctc ctctcctctc      120

cttggtgatc acaggtgtct ggtgcccttc agggacttga atccaagctc ggaagtcaac      180

accgcaaacc tactcgaatc tccttcaagt ctcttgctca cttcctgtta catctgtagc      240

tacttctctt tttacatatt aggagaaaag aggtgtcatt ctttgaaaag actaaggtac      300

agtgtatgtt gcaaggtgtg cccaaacttt tgtgcatgtg gaaaagaaaa tgtgtccggg      360

actggtcagg tttgcacggg agtgcacgta ggagccaagg agcaggagga gccaggagga      420

acccaagcat tgaggagctg cgggatctac tgcctggagg agaggacgga caaggccagc      480

catgaggagt gcagggagag gagcactttg ggaagaccac agtgcacagg actcacaccc      540

agccttgctg gagaaagccc atgccccagg cttcttccag gcagccccac tgtaagacat      600

ctcattgcct cttcctgccc tgggctgtct gacccactgc cccttccccc aggaacactt      660

ccactgggat ca                                                          672


<210>  5900
<211>  393
<212>  DNA
<213>  Homo Sapiens

<400>  5900
gtcccagcac ccaaggtccc tatcaagatg caagtcaaac actggccctc agagcaggac       60

ccagagaagg cctggggcgc ccgtgtggtg gagcctccgg agaaggacga ccagctggtg      120

gtgctgttcc ctgtccagaa gccgaaactc ttgaccaccg aggagaagcc acgaggtcag      180

ggcaggggcc ccatccttcc aggcaccaag gcctggatgg agaccgagga caccctgggc      240

cgtgtcctga gtcccgagcc cgaccatgac agcctgtacc accctccgcc tgaggaggac      300

cagggcgagg agaggccccg gttgtgggtg atgccaaatc accaggtgct cctgggaccg      360

gaggaagacc aagaccacat ctaccacccc cag                                   393


<210>  5901
<211>  2805
<212>  DNA
<213>  Homo Sapiens

<400>  5901
gaagatgggg aagtaagatc aagttgtcgt actgctccga cagatttagt tttcatctta       60

gatggctctt atagtgttgg cccagaaaac tttgaaatag tgaaaaagtg gcttgtcaat      120

atcacaaaaa actttgacat agggccgaag tttattcaag ttggagtggt tcaatatagt      180

gactaccctg tgctggagat tcctctcgga agctatgatt caggagaaca tttgacggca      240

gcagtggaat ccatactcta cttaggagga aacacaaaga cagggaaggc catccagttt      300

gcgctcgatt acctttttgc caagtcctca cgatttctga ctaagatagc agtggtactt      360

acggatggca agtcccaaga tgacgtcaag gatgcagctc aagcagcaag agatagtaag      420

ataacattat ttgctattgg tgttggttca gaaacagaag atgccgaact tagagctatt      480

gccaacaagc cttcgtctac ttatgtgttt tatgtggaag actatattgc aatatccaaa      540

ataagggaag tgatgaagca gaaactttgt gaagaatctg tctgtccaac acgaattcca      600

gtggcagctc gtgatgaaag gggatttgat attcttttag gtttagatgt aaataaaaag      660

gttaagaaaa gaatacagct ttcaccaaaa aagataaaag gatatgaagt aacatcaaaa      720

gttgatttat cagaactcac aagcaatgtt ttcccagaag gtcttcctcc atcatatgta      780

tttgtgtcta ctcaaagatt taaagtcaag aaaatttggg atttatggag aatattaact      840

attgatggaa ggccacaaat agcagttacc ttaaatggtg tggacaaaat cttattattt      900

acaacaacca gcgtaattaa tggctcacaa gtggttacct ttgctaaccc tcaagttaag      960

acgttgtttg atgaaggctg gcaccaaatt cgtctcttag taacagaaca agatgtgact     1020

ttgtatattg atgaccaaca aattgaaaac aagcccttac atccagtttt agggatcttg     1080

atcaatgggc aaacccaaat tggaaaatat tctggaaaag aagaaactgt tcagtttgat     1140

gtccaaaagt tgcgaatcta ctgtgaccca gaacagaaca accgggagac agcatgtgag     1200

attcctggat ttaatggaga gtgccttaat ggtcccagtg atgtaggttc aactccagct     1260

ccctgtattt gtcctccggg aaaaccagga cttcaaggcc ccaaaggtga ccctggactg     1320

cctgggaacc ctggctaccc tggacaacct ggtcaagatg gtaagcctgg atatcaggga     1380

attgcaggga caccaggtgt tccaggatct ccaggaatac aaggagctcg aggactacca     1440

ggttacaaag gagaaccagg gcgagatggt gacaagggtg atcgtggact tcctggtttt     1500

cctgggcttc atggcatgcc aggatcaaag ggtgaaatgg gtgccaaagg agacaaagga     1560

tcacctggat tttatggcaa aaagggtgca aaaggtgaaa aggggaatgc tggcttccct     1620

ggcctccctg gacctgctgg agaaccagga agacatggaa aggatggatt aatgggtagt     1680

cccggtttca agggagaagc aggatcccct ggtgctccgg ggcaggatgg aacacgggga     1740

gagcctggaa tcccaggatt tcctggaaac cgaggattaa tgggccaaaa gggagaaatt     1800

gggcctccag gacagcaagg aaaaaaagga gccccaggga tgcctggttt aatgggaagc     1860

aatggctcac caggccagcc tggaacaccg ggatctaagg gaagcaaagg tgaacctgga     1920

attcaaggga tgcctggggc ttctgggctc aagggagaac caggagcaac gggttcccca     1980

ggagaaccag gatacatggg tttacccggg attcaaggaa aaaaggggga caaaggaaat     2040

caaggtgaaa aaggtattca gggtcaaaag ggagaaaatg gaagacaggg aattccaggg     2100

caacagggaa ttcaaggcca tcatggtgca aaaggagaga gaggtgaaaa gggagaacct     2160

ggtgtccgag gtgccattgg atcaaaagga gaatctgggg tggatggctt gatggggccc     2220

gcaggtccta aggggcaacc tggggatcca ggtcctcagg gacccccagg tttggatggg     2280

aagcccggaa gagagttttc agaacaattt attcgacaag tttgcacaga tgtaataaga     2340

gcccagctac cagtcttact tcagagtgga agaattagaa attgtgatca ttgcctgtcc     2400

caacatggct ccccgggtat tcctgggcca cctggtccga taggcccaga gggtcccaga     2460

ggattacctg gtttgccagg aagagatggt gttcctggat tagtgggtgt ccctggacgt     2520

ccaggtgtca gaggattaaa aggcctacca ggaagaaatg gggaaaaagg gagccaaggg     2580

tttgggtatc ctggagaaca aggtcctcct ggtcccccag gtccagaggg ccctcctgga     2640

ataagcaaag aaggtcctcc aggagaccca ggtctccctg gcaaagatgg agaccatgga     2700

aaacctggaa tccaagggca accaggcccc ccaggcatct gcgacccatc actatgtttt     2760

agtgtaattg ccagaagaga tccgttcaga aaaggaccaa actat                     2805


<210>  5902
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  5902
cagattagtc ctaaagaagg gtggcaggtg tacagctcag ctcaggatcc tgatgggcgg       60

tgcatttgta cagttgttgc tccagaacaa aacctgtgtt cccgggatgc caaaagcagg      120

caacttcgca aactactgga aaaggttcag aacatgtccc agtctattga agtcttaaac      180

ttgagaactc agagagattt ccaatatgtt ttaaaaatgg aaacccaaat gaaagggctg      240

aaggcaaaat ttcggcagat tgaagatgat cgaaagacac ttatgaccaa gcattttcag      300

gagttgaaag agaaaatgga cgagctcctg cctttgatcc ccgtgctgga acagtacaaa      360

acagatgcta agttaatcac ccagttcaag gaggaaataa ggaatctgtc tgctgtcctc      420

actggtattc aggaggaaat tggtgcctat gactacgagg aactacacca aagagtgctg      480

agcttggaaa caagacttcg tgactgcatg aaaaagctaa catgtggcaa actgatgaaa      540

atcacaggcc cagttacagt caagacatct ggaacccgat ttggtgcttg gatgacagac      600

cctttagcat ctgagaaaaa caacagagtc tggtacatgg acagttatac taacaataaa      660

attgttcgtg aatacaaatc aattgcagac tttgtcagtg gggctgaatc aaggacatac      720

aaccttcctt tcaagtgggc aggaactaac catgttgtct acaatggctc actctatttt      780

aacaagtatc agagtaatat catcatcaaa tacagctttg atatggggag agtgcttgcc      840

caacgaagcc tggagtatgc tggttttcat aatgtttacc cctacacatg gggtggattc      900

tctgacatcg acctaatggc tgatgaaatc gggctgtggg ctgtgtatgc aactaaccag      960

aatgcaggca atattgtcat cagccaactt aaccaagata ccttggaggt gatgaagagc     1020

tggagcactg gctaccccaa gagaagtgca ggggaatctt tcatgatctg tgggacactg     1080

tatgtcacca actcccactt aactggagcc aaggtgtatt attcctattc caccaaaacc     1140

tccacatatg agtacacaga cattcccttc cataaccaat actttcacat atccatgctt     1200

gactacaatg caagagatcg agctctctgt gcctggaaca atggccacca ggtgctgttc     1260

aatgtcaccc ttttccatat catcaagaca gaggatgaca ca                        1302


<210>  5903
<211>  1758
<212>  DNA
<213>  Homo Sapiens

<400>  5903
ctggagagta caaaactgct ggcagacctt aaaaaatgtg gtgacttgga atgtgaagct       60

ttaataaaca gagtctcagc catgagagat tatagaggac ctgactgccg atacctgaac      120

ttcactaagg gagaagagat atctgtttat gttaaacttg caggagaaag ggaagatttg      180

tgggcaggaa gtaaaggaaa ggagtttgga tattttccca gagatgcagt ccagattgaa      240

gaggtgttca tatctgagga aattcagatg tcaacgaaag aatctgactt tctttgtctt      300

cttggagtaa gttacacatt tgacaatgaa gatagtgaat taaacggtga ttatggtgaa      360

aatatatatc cttatgaaga agataaagat gaaaaatcta gtatatatga aagtgatttt      420

cagatagaac ctggatttta tgcaacttat gaaagtactt tgtttgaaga ccaagttcca      480

gcattagagg ctcctgaaga tatcggaagt accagtgaat caaaagactg ggaagaagta      540

gttgttgaaa gtatggaaca ggatcgtatt ccagaagtgc atgtcccacc atcttcagct      600

gtgtctggag tcaaagaatg gtttggattg ggaggagaac aagctgaaga gaaggctttt      660

gaatcagtta ttgaacctgt acaagaaagc tcatttcgga gtagaaaaat agcagtggaa      720

gatgagaatg acctagagga attaaataat ggtgagcctc aaacagaaca tcagcaagaa      780

tctgaatcag aaattgattc agtgccaaag acacagtctg aactagcatc tgagtcagag      840

cacattccca aacctcaatc cactggttgg tttggtggag gatttacaag ttatttaggt      900

tttggagatg aggatacagg gcttgaatta atagctgaag aaagcaatcc accactacaa      960

gattttccca attccatatc atctgataaa gaagccacag ttccatgtac agaaatatta     1020

acagaaaaaa aagacacaat cactaatgat agcttgagtc tcaagccaag ttggtttgat     1080

tttggttttg ctatactagg ctttgcatat gccaaggaag ataaaattat gttagatgac     1140

aggaaaaatg aagaagatgg tggggcagat gaacatgaac atcctctaac aagtgaatta     1200

gaccctgaaa aagaacaaga aatagaaacg ataaaaatta tagaaacaga agatcaaata     1260

gacaagaaac cagtctcaga aaaaacagac gaatctgata ctataccata tttgaaaaag     1320

ttcttgtata attttgacaa cccttggaac ttccagaaca ttccaaagga aacagaattg     1380

ccatttccca aacagatact ggatcaaaat aatgtaattg aaaatgaaga aactggagaa     1440

ttttccattg ataattatcc cacagataat acaaaagtta tgatattcaa aagttcatac     1500

agtctgtcag atatggtctc taacatagag ttacctacga gaattcacga agaagtatat     1560

tttgaaccct catcttctaa agatagtgat gaaaattcga aaccatcagt agacaccgaa     1620

gggcctgctc tggtggagat agacagatct gtggaaaata ccctgctaaa tagtcagatg     1680

gtttcaactg ataactcttt gtcttctcaa aattatattt ctcagaaaga agatgcttct     1740

gagtttcaga ttctgaaa                                                   1758


<210>  5904
<211>  1386
<212>  DNA
<213>  Homo Sapiens

<400>  5904
cagcaaggtg atggatgtgg acacactgta ctaggccctg agagtggaac ccttacatcc       60

ataaactacc cacagaccta tcccaacagc actgtttgtg aatgggagat ccgtgtaaag      120

atgggagaga gagttcgcat caaatttggt gactttgaca ttgaagattc tgattcttgt      180

cactttaatt acttgagaat ttataatgga attggagtca gcagaactga aataggcaaa      240

tactgtggtc tggggttgca aatgaaccat tcaattgaat caaaaggcaa tgaaatcaca      300

ttgctgttca tgagtggaat ccatgtttct ggacgcggat ttttggcctc atactctgtt      360

atagataaac aagatctaat tacttgtttg gacactgcat ccaatttttt ggaacctgag      420

ttcagtaagt actgcccagc tggttgtctg cttccttttg ctgagatatc tggaacaatt      480

cctcatggat atagagattc ctcgccattg tgcatggctg gtgtgcatgc aggagtagtg      540

tcaaacacgt tgggcggcca aatcagtgtt gtaattagta aaggtatccc ctattatgaa      600

agttctttgg ctaacaacgt cacatctgtg gtgggacact tatctacaag tctttttaca      660

tttaagacaa gtggatgtta tggaacactg gggatggagt ctggtgtgat cgcggatcct      720

caaataacag catcatctgt gctggagtgg actgaccaca cagggcaaga gaacagttgg      780

aaacccaaaa aagccaggct gaaaaaacct ggaccgcctt gggctgcttt tgccactgat      840

gaataccagt ggttacaaat agatttgaat aaggaaaaga aaataacagg cattataacc      900

actggatcca ccatggtgga gcacaattac tatgtgtctg cctacagaat cctgtacagt      960

gatgatgggc agaaatggac tgtgtacaga gagcctggtg tggagcaaga taagatattt     1020

caaggaaaca aagattatca ccaggatgtg cgtaataact ttttgccacc aattattgca     1080

cgttttatta gagtgaatcc tacccaatgg cagcagaaaa ttgccatgaa aatggagctg     1140

ctcggatgtc agtttattcc taaaggtcgt cctccaaaac ttactcaacc tccacctcct     1200

cggaacagca atgacctcaa aaacactaca gcccctccaa aaatagccaa aggtcgtgcc     1260

ccaaaattta cgcaaccact acaacctcgc agtagcaatg aatttcctgc acagacagaa     1320

caaacaactg ccagtcctga tatcagaaat actaccgtaa ctccaaatgt aaccaaagat     1380

gtagcg                                                                1386


<210>  5905
<211>  483
<212>  DNA
<213>  Homo Sapiens

<400>  5905
tacaggcacc agaaaagaaa gcatacttgc cccagctgcc agcactcctg gatcgaaggt       60

gtccaagaca acatgaagct ccataaggtg gactttatct ggatcaacag agaccagcgg      120

tctttcgagt ggtttgtgag cctgctgact aaactggaga tggaccaggc cgaggaggct      180

caatacggcc gcttcctgga gctgcatatg tacatgacat ctgcactggg caagaatgac      240

atgaaggcca ttggcctgca gatggccctt gacctcctgg ccaacaagga gaagaaagac      300

tccatcacgg ggctgcagac gcgcacccag cctgggcggc ctgactggag caaggtgttc      360

cagaaagtgg ctgctgagaa gaagggcaag gtgcaggtct tcttctgtgg ctccccagct      420

ctggccaagg tgctgaaggg ccattgtgag aagttcggct tcagattttt ccaagagaat      480

ttc                                                                    483


<210>  5906
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  5906
ttcctcatca acaaagtgcc ccttcctgtt gacaagttgg cacctttacc tctggacaac       60

attcttccct ttatggatcc attaaagctt cttctgaaaa ctctgggcat ttctgttgag      120

caccttgtgg aggggctaag gaagtgtgta aatgagctgg gaccagaggc ttctgaagct      180

gtgaagaaac tgctggaggc gctatcacac ttggtg                                216


<210>  5907
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  5907
aaatcgtgtg ctccaaataa agcagatgtc attcttgtgt tttgctatcc caaaaccatc       60

atcaccaaaa tccccgagtg tccctatgga tgggaagttc atcagctggc cctcggaggg      120

ctgtgttaca atggggtcca cgaaggaggt tactaccaat ttgtgatccc agatttatca      180

cctaaaaaca agtcctattg tggaacccag tctgagtaca agccacctat ctatcacttc      240

tacagtcaca tcgtttccaa tgacaccaca gtgattgtaa aaaaccagcc tgtcaactac      300

tccttctcct gcacctacca ctccacctac ttggtgaacc aggctgcctt tgaccagaga      360

gtggccactg ttcacgtgaa gaacgggagc atgggcacat ttgagagcca actgtctctc      420

aacttctaca ctaatgccaa gttctccatc aagaaagaag ctccctttgt cctggaggca      480

tcggaaatcg gttcagatct gtttgcagga gtggaagcca aagggttaag cattaggttt      540

aaagtggtct tgaacagctg ttgggccacc ccctcggctg acttcatgta tcccttgcag      600

tggcagctga tcaacaaggg ctgccccacg gatgaaaccg tcctcgtgca tgagaatggg      660

agagatcaca gggcaacctt ccaattcaat gctttccggt tccagaacat ccccaaactc      720

tccaaggtgt ggttacactg tgagacgttc atctgcgaca gtgagaaact ctcctgccca      780

gtgacctgcg ataaacggaa gcgcctcctg cgagaccaga ccgggggagt cctggttgtg      840

gagctctccc tgcggagcag ggga                                             864


<210>  5908
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  5908
tgcgggattc cactcaaccc tgcccgggac ctgggcccac gtctcttcac ctacgtggct       60

ggctggggtc ctgaagtctt cagtgctggt aatggctggt ggtgggtgcc tgtggtggcc      120

cctctggtgg gggccaccgt tggcacagcc acttaccagc tgttggtggc tctgcaccac      180

cctgagggcc cagagccagc tcaggatctg gtgtctgctc aacacaaagc ctcagagttg      240

gaaactcccg cctcagctca gatgctggag tgtaagcta                             279


<210>  5909
<211>  2487
<212>  DNA
<213>  Homo Sapiens

<400>  5909
atcacatgtg gtcaccctgg aaaccctgcc cacggattca ctaatggcag tgagttcaac       60

ctgaatgatg tcgtgaattt cacctgcaac acgggctatt tgctgcaggg cgtgtctcga      120

gcccagtgtc ggagcaacgg ccagtggagt agccctctgc ccacgtgtcg agtggtgaac      180

tgttctgatc caggctttgt ggaaaatgcc attcgtcacg ggcaacagaa cttccctgag      240

agttttgagt atggaatgag tatcctgtac cattgcaaga agggatttta cttgctggga      300

tcttcagcct tgacctgtat ggcaaatggc ttatgggacc gatccctgcc caagtgtttg      360

gctatatcct gtggacaccc aggggtccct gccaacgccg tcctcactgg agagctgttt      420

acctatggcg ccgtcgtgca ctactcctgc agagggagcg agagcctcat aggcaacgac      480

acgagagtgt gccaggaaga cagtcactgg agcggggcac tgccccactg cacaggaaat      540

aatcctggat tctgtggtga tccggggacc ccagcacatg ggtctcggct tggtgatgac      600

tttaagacaa agagtcttct ccgcttctcc tgtgaaatgg ggcaccagct gaggggctcc      660

cctgaacgca cgtgtttgct caatgggtca tggtcaggac tgcagccggt gtgtgaggcc      720

gtgtcctgtg gcaaccctgg cacacccacc aacggaatga ttgtcagtag tgatggcatt      780

ctgttctcca gctcggtcat ctatgcctgc tgggaaggct acaagacctc agggctcatg      840

acacggcatt gcacagccaa tgggacctgg acaggcactg ctcccgactg cacaattata      900

agttgtgggg atccaggcac actagcaaat ggcatccagt ttgggaccga cttcaccttc      960

aacaagactg tgagctatca gtgtaaccca ggctatgtca tggaagcagt cacatccgcc     1020

actattcgct gtaccaaaga cggcaggtgg aatccgagca aacctgtctg caaagccgtg     1080

ctgtgtcctc agccgccgcc ggtgcagaat ggaacagtgg agggaagtga tttccgctgg     1140

ggctccagca taagttacag ctgcatggac ggttaccagc tctctcactc cgccatcctc     1200

tcctgtgaag gtcgcggggt gtggaaagga gagatccccc agtgtctccc tgtgttctgc     1260

ggagaccctg gcatccccgc agaagggcga cttagtggga aaagtttcac ctataagtcc     1320

gaagtcttct tccagtgcaa atctccattt atactcgtgg gatcctccag aagagtctgc     1380

caagctgacg gcacgtggag cggcatacaa cccacctgca ttgatcctgc tcataacacc     1440

tgcccagacc ctggtacgcc acactttgga atacagaata gctccagagg ctatgaggtt     1500

ggaagcacgg tttttttcag gtgcagaaaa ggctaccata ttcaaggttc cacgactcgc     1560

acctgccttg ccaatttaac atggagtggg atacagaccg aatgtatacc tcatgcctgc     1620

agacagccag aaaccccggc acacgcggat gtgagagcca tcgatcttcc tactttcggc     1680

tacaccttag tgtacacctg ccatccaggc tttttcctcg cagggggatc tgagcacaga     1740

acatgtaaag cagacatgaa atggacagga aagtcgcctg tgtgtaaaag taaaggagtg     1800

agagaagtta atgaaacagt tactaaaact ccagttcctt cagatgtctt tttcgtcaat     1860

tcactgtgga aggggtatta tgaatattta gggaaaagac aacccgccac tctaactgtt     1920

gactggttca atgcaacaag cagtaaggtg aatgccacct tcagcgaagc ctcgccagtg     1980

gagctgaagt tgacaggcat ttacaagaag gaggaggccc acttactcct gaaagctttt     2040

caaattaaag gccaggcaga tatttttgta agcaagttcg aaaatgacaa ctggggacta     2100

gatggttatg tgtcatctgg acttgaaaga ggaggattta cttttcaagg tgacattcat     2160

ggaaaagact ttggaaaatt taagctagaa aggcaagatc ctttaaaccc agatcaagac     2220

tcttccagtc attaccacgg caccagcagt ggctctgtgg cggctgccat tctggttcct     2280

ttctttgctc taattttatc agggtttgca ttttacctct acaaacacag aacgagacca     2340

aaagttcaat acaatggcta tgctgggcat gaaaacagca atggacaagc atcgtttgaa     2400

aaccccatgt atgatacaaa cttaaaaccc acagaagcca aggctgtgag gtttgacaca     2460

actctgaaca cagtctgtac agtggta                                         2487


<210>  5910
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  5910
aagaaatttc aggttccgtg tcctgtggaa gctgctttga taattaacga aacaataaac       60

accaccttaa cacagccaac agctcttgta cctgctttgt cacataacgt gactgaaaat      120

gactcttgca gacctcacta ttttattttc aactcacaga ct                         162


<210>  5911
<211>  282
<212>  DNA
<213>  Homo Sapiens

<400>  5911
tcagcccaag tttccccacg catcactttt aagccaatag ctccgtcagg tcagaacgcc       60

acttgcacaa gatacagtta ctgtaatgaa tgtatgttgg atccagactg cggtttctgc      120

tacaagatga acaaatcaac tgtcattgac tcctcctgtg ttccagttaa taaagcatct      180

acaaatgagg cagcctgggg caggtgtgaa aatgaaacca agttcaaaac agaagatata      240

ttttgggctt acaatttctg ccctactcca tactcctgga ct                         282


<210>  5912
<211>  252
<212>  DNA
<213>  Homo Sapiens

<400>  5912
ttcttagtgg gctcggccaa gcctgtggcc cagcctgtcg ctgcgctgga gtcggcggcg       60

gaggccgggg ccgggaccct ggccaacccc ctcggcaccc tcaacccgct gaagctcctg      120

ctgagcagcc tgggcatccc cgtgaaccac ctcatagagg gctcccagaa gtgtgtggct      180

gagctgggtc cccaggccgt gggggccgtg aaggccctga aggccctgct gggggccctg      240

acagtgtttg gc                                                          252


<210>  5913
<211>  159
<212>  DNA
<213>  Homo Sapiens

<400>  5913
gggtctccga tcagctgctt ctctcccagt aacttcagca tccggcaggc agcctacgtg       60

gacagctcct gctgggactc actgcttcac cataagcagg acgggcctgg ccaggacaaa      120

atgaaatctc tctggcccca caaggccctc ccctactcc                             159


<210>  5914
<211>  1638
<212>  DNA
<213>  Homo Sapiens

<400>  5914
caggactgga aggctgaacg cagccaagac cccttcgaga aatgcatgca ggatcctgac       60

tatgagcagc tgctcaaggt ggtgacctgg gggctcaatc ggaccctgaa gccccagagg      120

gtgattgtgg ttggcgctgg tgtggccggg ctggtggccg ccaaggtgct cagcgatgct      180

ggacacaagg tcaccatcct ggaggcagat aacaggatcg ggggccgcat cttcacctac      240

cgggaccaga acatgggctg gattggggag ctgggagcca tgcgcatgcc cagctctcac      300

aggatcctcc acaagctctg ccagggcctg gggctcaacc tgaccaagtt cacccagtac      360

gacaagaaca cgtggacgga ggtgcacgaa gtgaagctgc gcaactatgt ggtggagaag      420

gtgcccgaga agctgggcta cgccttgcgt ccccaggaaa agggccactc gcccgaagac      480

atctaccaga tggctctcaa ccaggccctc aaagacctca aggcactggg ctgcagaaag      540

gcgatgaaga agtttgaaag gcacacgctc ttggaatatc ttctcgggga ggggaacctg      600

agccggccgg ccgtgcagct tctgggagac gtgatgtccg aggatggctt cttctatctc      660

agcttcgccg aggccctccg ggcccacagc tgcctcagcg acagactcca gtacagccgc      720

atcgtgggtg gctgggacct gctgccgcgc gcgctgctga gctcgctgtc cgggcttgtg      780

ctgttgaacg cgcccgtggt ggcgatgacc cagggaccgc acgatgtgca cgtgcagatc      840

gagacctctc ccccggcgcg gaatctgaag gtgctgaagg ccgacgtggt gctgctgacg      900

gcgagcggac cggcggtgaa gcgcatcacc ttctcgccgc cgctgccccg ccacatgcag      960

gaggcgctgc ggaggctgca ctacgtgccg gccaccaagg tgttcctaag cttccgcagg     1020

cccttctggc gcgaggagca cattgaaggc ggccactcaa acaccgatcg cccgtcgcgc     1080

atgattttct acccgccgcc gcgcgagggc gcgctgctgc tggcctcgta cacgtggtcg     1140

gacgcggcgg cagcgttcgc cggcttgagc cgggaagagg cgttgcgctt ggcgctcgac     1200

gacgtggcgg cattgcacgg gcctgtcgtg cgccagctct gggacggcac cggcgtcgtc     1260

aagcgttggg cggaggacca gcacagccag ggtggctttg tggtacagcc gccggcgctc     1320

tggcaaaccg aaaaggatga ctggacggtc ccttatggcc gcatctactt tgccggcgag     1380

cacaccgcct acccgcacgg ctgggtggag acggcggtca agtcggcgct gcgcgccgcc     1440

atcaagatca acagccggaa ggggcctgca tcggacacgg ccagccccga ggggcacgca     1500

tctgacatgg aggggcaggg gcatgtgcat ggggtggcca gcagcccctc gcatgacctg     1560

gcaaaggaag aaggcagcca ccctccagtc caaggccagt tatctctcca aaacacgacc     1620

cacacgagga cctcgcat                                                   1638


<210>  5915
<211>  330
<212>  DNA
<213>  Homo Sapiens

<400>  5915
catcacttgc cagacagaag tcaactgtgt cggaaggtca agttccaggt ggacttcaac       60

ctgatcggat ggggctcctg gatcatctac cccaagcagt acaacgccta tcgctgtgag      120

ggcgagtgtc ctaatcctgt tggggaggag tttcatccga ccaaccatgc atacatccag      180

agtctgctga aacgttacca gccccaccga gtcccttcca cttgttgtgc cccagtgaag      240

accaagccgc tgagcatgct gtatgtggat aatggcagag tgctcctaga tcaccataaa      300

gacatgatcg tggaagaatg tgggtgcctc                                       330


<210>  5916
<211>  348
<212>  DNA
<213>  Homo Sapiens

<400>  5916
catgatgatg actggattga ccccacagac atgcttaact atgatgctgc ttcaggaaca       60

atgagaaaat ctcaggcaaa atatggtatt tcaggggaaa aggatgtcag tcctgacttg      120

tcatgtgctg atgaaatatc agaatgttat cacaaacttg attctttaac ttataagatt      180

gatgagtgtg aaaagaaaaa gagggaagac tatgaaagtc aaagcaatcc tgtttttagg      240

agatacttaa ataagatttt aattgaagct ggaaagcttg gactttttca tgattttgaa      300

acatggaagt ggcgattcga agattccttt ggagtggatc catataat                   348


<210>  5917
<211>  504
<212>  DNA
<213>  Homo Sapiens

<400>  5917
cagcaggagc aggacttcta cgacttcaag gcggtcaaca tccggggcaa actggtgtcg       60

ctggagaagt accgcggatc ggtgtccctg gtggtgaatg tggccagcga gtgcggcttc      120

acagaccagc actaccgagc cctgcagcag ctgcagcgag acctgggccc ccaccacttc      180

aacgtgctcg ccttcccctg caaccagttt ggccaacagg agcctgacag caacaaggag      240

attgagagct ttgcccgccg cacctacagt gtctcattcc ccatgtttag caagattgca      300

gtcaccggta ctggtgccca tcctgccttc aagtacctgg cccagacttc tgggaaggag      360

cccacctgga acttctggaa gtacctagta gccccagatg gaaaggtggt aggggcttgg      420

gacccaactg tgtcagtgga ggaggtcaga ccccagatca cagcgctcgt gaggaagctc      480

atcctactga agcgagaaga ctta                                             504


<210>  5918
<211>  318
<212>  DNA
<213>  Homo Sapiens

<400>  5918
caggaggcag tcatcccagg ctgccacttg caccccttca atgtgacagt gcgaagtgac       60

cgccaaggca cctgccaggg ctcccacgtg gcacaggcct gtgtgggcca ctgtgagtcc      120

agcgccttcc cttctcggta ctctgtgctg gtggccagtg gttaccgaca caacatcacc      180

tccgtctctc agtgctgcac catcagtggc ctgaagaagg tcaaagtaca gctgcagtgt      240

gtggggagcc ggagggagga gctcgagatc ttcacggcca gggcctgcca gtgtgacatg      300

tgtcgcctct ctcgctac                                                    318


<210>  5919
<211>  525
<212>  DNA
<213>  Homo Sapiens

<400>  5919
atgcctctac cacctcatcc tgggcaccct ggttatatca acttcagcta tgaggtgctt       60

acccctttga agtggtacca gagcataagg ccaccgtacc cttcctatgg ttacgagccc      120

atgggtggat ggctgcacca ccaaatcatc cccgtgctgt cccaacagca ccccccgact      180

cacaccctgc agcctcatca ccacatccca gtggtgccag ctcagcagcc cgtgatcccc      240

cagcaaccaa tgatgcccgt tcctggccaa cactccatga ctccaatcca acaccaccag      300

ccaaacctcc ctccgcccgc ccagcagccc taccagcccc agcctgttca gccacagcct      360

caccagccca tgcagcccca gccacctgtg caccccatgc agcccctgcc gccacagcca      420

cctctgcctc cgatgttccc catgcagccc ctgcctccca tgcttcctga tctgactctg      480

gaagcttggc catcaacaga caagaccaag cgggaggaag tggat                      525


<210>  5920
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  5920
atgcctctac cacctcatcc tgggcaccct ggttatatca acttcagcta tgaggtgctc       60

acccctttga agtggtacca gagcatgata agaccaccat actcttccta tggttacgag      120

cccatgggtg gatggctgca ccaccaaatc atccccgtgg tgtcccaaca gcaccccctg      180

actcacaccc tgcagtctca tcaccacatc ccagtggtgc cagctcagca gcccagggtc      240

cgccagcaag cactgatgcc tgttcctggc cagcaatcca tgactccaac ccaacaccat      300

cagccaaacc tccctctgcc tgcccagcag cccttccagc cccagcctgt tcagccacag      360

cctcaccagc ccatgcagcc ccagccacct gtgcaaccca tgcagcccct gctgccacag      420

ccacctctgc ctccaatgtt ccccctgcgg cccctgcccc ccatacttcc tgatctgcat      480

ctggaagctt ggccagcaac agacaagacc aagcaggagg aagtggat                   528


<210>  5921
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  5921
tccagcctgg gtgtcgttac ttgcggctcc gtggtgaagc tactcaatac gcgccacaac       60

gtccgactgc actcacacga cgtgcgctat gggtcaggta gtgggcagca gtcagtgaca      120

ggtgtaacct ctgtggatga cagcaacagt tactggagga tacgggggaa gagtgccaca      180

gtgtgtgaga ggggaacccc catcaagtgt ggccagccca tccggctgac acatgtcaac      240

actggccgaa acctccatag tcaccacttc acttcacctc tttctggaaa ccaggaagtg      300

agtgcttttg gtgaggaagg tgaaggtgat tatctggatg actggacagt gctctgtaat      360

ggaccctact gggtgagaga tggtgaggtg cggttcaaac actcttccac tgaggtactg      420

ctgtctgtca caggagaaca atatggtcga cctatcagtg ggcaaaaaga ggtgcatggc      480

atggcccagc caagtcagaa caactactgg aaagccatgg aaggcatctt catgaagccc      540

agtgagttgt tgaaggcaga agcccaccat gcagagctg                             579


<210>  5922
<211>  1104
<212>  DNA
<213>  Homo Sapiens

<400>  5922
gagaacgact tcggtctggt gcagccgctg gtgaccatgg agcaactgct gtgggtgagc       60

gggagacaga tcggctcagt ggacaccttc cgcatcccgc tcatcacagc cactccgcgg      120

ggcactcttc tcgcctttgc tgaggcgagg aaaatgtcct catccgatga gggggccaag      180

ttcatcgccc tgcggaggtc catggaccag ggcagcacat ggtctcctac agcgttcatt      240

gtcaatgatg gggatgtccc cgatgggctg aaccttgggg cagtagtgag cgatgttgag      300

acaggagtag tatttctttt ctactccctt tgtgctcaca aggccggctg ccaggtggcc      360

tctaccatgt tggtatggag caaggatgat ggtgtttcct ggagcacacc ccggaatctc      420

tccctggata ttggcactga agtgtttgcc cctggaccgg gctctggtat tcagaaacag      480

cgggagccac ggaagggccg cctcatcgtg tgtggccatg ggacgctgga gcgggacgga      540

gtcttctgtc tcctcagcga tgatcatggt gcctcctggc gctacggaag tggggtcagc      600

ggcatcccct acggtcagcc caagcaggaa aatgatttca atcctgatga atgccagccc      660

tatgagctcc cagatggctc agtcgtcatc aatgcccgaa accagaacaa ctaccactgc      720

cactgccgaa ttgtcctccg cagctatgat gcctgtgata cactaaggcc ccgtgatgtg      780

accttcgacc ctgagctcgt ggaccctgtg gtagctgcag gagctgtagt caccagctcc      840

ggcattgtct tcttctccaa cccagcacat ccagagttcc gagtgaacct gaccctgcga      900

tggagcttca gcaatggtac ctcatggcgg aaagagacag tccagctatg gccaggcccc      960

agtggctatt catccctggc aaccctggag ggcagcatgg atggagagga gcaggccccc     1020

cagctctacg tcctgtatga gaaaggccgg aaccactaca cagagagcat ctccgtggcc     1080

aaaatcagtg tctatgggac actc                                            1104


<210>  5923
<211>  2034
<212>  DNA
<213>  Homo Sapiens

<400>  5923
agcgcgccgg gcgaggacga ggagtgcggc cgggtccggg acttcgtcgc caagctggcc       60

aacaacacgc accagcatgt gtttgatgat ctcagaggct cagtatcctt gtcctgggtt      120

ggagatagca ctggggtcat tctagtcttg actaccttcc atgtaccact ggtaattatg      180

acttttggac agtccaagct atatcgaagt gaggattatg ggaagaactt taaggatatt      240

acagatctca tcaataacac ctttattcgg actgaatttg gcatggctat tggtcctgag      300

aactctggaa aggtggtgtt aacagcagag gtgtctggag gaagtcgtgg aggaagaatc      360

ttcagatcat cagattttgc gaagaatttt gtgcaaacag atctcccttt tcatcctctc      420

actcagatga tgtatagccc tcagaattct gattatcttt tagctctcag cactgaaaat      480

ggcctgtggg tgtccaagaa ttttggggga aaatgggaag aaatccacaa agcagtatgt      540

ttggccaaat ggggatcaga caacaccatc ttctttacaa cctatgcaaa tggctcctgc      600

aaagctgacc ttggggctct ggaattatgg agaacttcag acttgggaaa aagcttcaaa      660

actattggtg tgaaaatcta ctcatttggt cttgggggac gtttcctttt tgcctctgtg      720

atggctgata aggataccac aagaaggatc cacgtttcaa cagatcaagg ggacacatgg      780

agcatggccc agctcccctc cgtgggacag gaacagttct attctattct ggcagcaaat      840

gatgacatgg tattcatgca tgtagatgaa cctggagaca ctgggtttgg cacaatcttt      900

acctcagatg atcgaggcat tgtctattcc aagtctttgg accgacatct ctacactacc      960

acaggcggag agacggactt taccaacgtg acctccctcc gcggcgtcta cataacaagc     1020

gtgctctccg aagataattc tatccagacc atgatcactt ttgaccaagg aggaaggtgg     1080

acgcacctga ggaagcctga aaacagtgaa tgtgatgcta cagcaaaaaa caagaatgag     1140

tgcagccttc atattcatgc ttcctacagc atctcccaga aactgaatgt tccaatggcc     1200

ccactctcag agccgaatgc cgtaggcatt gtcattgctc atggtagcgt gggggatgcc     1260

atctcagtga tggttccaga tgtgtacatc tcagatgatg ggggttactc ctggacaaag     1320

atgctggaag gaccccacta ttacaccatc ctggattctg gaggcatcat tgtggccatt     1380

gagcacagca gccgtcctat caatgtgatt aagttctcca cagacgaagg tcaatgctgg     1440

caaacctaca cgttcaccag ggaccccatc tatttcactg gcctagcttc agaacctgga     1500

gctaggtcca tgaatatcag catttggggc ttcacagaat ctttcctgac cagccagtgg     1560

gtctcctaca ccattgattt taaagatatc cttgaaagga actgtgaaga gaaggactat     1620

accatatggc tggcacactc cacagaccct gaagattatg aagatggctg cattttgggc     1680

tacaaagaac agtttctgcg gctacgcaag tcatccgtgt gtcagaatgg tcgagactat     1740

gttgtgacca agcagccctc catctgcctc tgttccctgg aggactttct ctgtgatttt     1800

ggctactacc gtccagaaaa tgactccaag tgtgtggaac agccagaact gaagggccac     1860

gacctggagt tttgtctgta cggaagagaa gaacacctaa caacaaatgg gtaccggaaa     1920

attccagggg acaaatgcca gggtggggta aatccagttc gagaagtaaa agacttgaaa     1980

aagaaatgca caagcaactt tttgagtccg gaaaaacaga attccaagtc aaat           2034


<210>  5924
<211>  918
<212>  DNA
<213>  Homo Sapiens

<400>  5924
attcctatag atgatcctga agatggaggc aagcactggg tggtgatcgt ggcaggttca       60

aatggctggt ataattatag gcaccaggca gacgcgtgcc atgcctacca gatcattcac      120

cgcaatggga ttcctgacga acagatcgtt gtgatgatgt acgatgacat tgcttactct      180

gaagacaatc ccactccagg aattgtgatc aacaggccca atggcacaga tgtctatcag      240

ggagtcccga aggactacac tggagaggat gttaccccac aaaatttcct tgctgtgttg      300

agaggcgatg cagaagcagt gaagggcata ggatccggca aagtcctgaa gagtggcccc      360

caggatcacg tgttcattta cttcactgac catggatcta ctggaatact ggtttttccc      420

aatgaagatc ttcatgtaaa ggacctgaat gagaccatcc attacatgta caaacacaaa      480

atgtaccgaa agatggtgtt ctacattgaa gcctgtgagt ctgggtccat gatgaaccac      540

ctgccggata acatcaatgt ttatgcaact actgctgcca accccagaga gtcgtcctac      600

gcctgttact atgatgagaa gaggtccacg tacctggggg actggtacag cgtcaactgg      660

atggaagact cggacgtgga agatctgact aaagagaccc tgcacaagca gtaccacctg      720

gtaaaatcgc acaccaacac cagccacgtc atgcagtatg gaaacaaaac aatctccacc      780

atgaaagtga tgcagtttca gggtatgaaa cgcaaagcca gttctcccgt ccccctacct      840

ccagtcacac accttgacct cacccccagc cctgatgtgc ctctcaccat catgaaaagg      900

aaactgatga acaccaat                                                    918


<210>  5925
<211>  1233
<212>  DNA
<213>  Homo Sapiens

<400>  5925
tacctgttgc tgggccgctg gagaaagaag cacctgactt tccgcatctt gaacctgccc       60

tccacccttc caccccacac agcccgggca gccctgcgtc aagccttcca ggactggagc      120

aatgtggctc ccttgacctt ccaagaggtg caggctggtg cggctgacat ccgcctctcc      180

ttccatggcc gccaaagctc gtactgttcc aatacttttg atgggcctgg gagagtcctg      240

gcccatgccg acatcccaga gctgggcagt gtgcacttcg acgaagacga gttctggact      300

gaggggacct accgtggggt gaacctgcgc atcattgcag cccatgaagt gggccatgct      360

ctggggcttg ggcactcccg atattcccag gccctcatgg ccccagtcta cgagggctac      420

cggccccact ttaagctgca cccagatgat gtggcaggga tccaggctct ctatggcaag      480

aagagtccag tgataaggga tgaggaagaa gaagagacag agctgcccac tgtgccccca      540

gtgcccacag aacccagtcc catgccagac ccttgcagta gtgaactgga tgccatgatg      600

ctggggcccc gtgggaagac ctatgctttc aagggggact atgtgtggac tgtatcagat      660

tcaggaccgg gccccttgtt ccgagtgtct gccctttggg aggggctccc cggaaacctg      720

gatgctgctg tctactcgcc tcgaacacaa tggattcact tctttaaggg agacaaggtg      780

tggcgctaca ttaatttcaa gatgtctcct ggcttcccca agaagctgaa tagggtagaa      840

cctaacctgg atgcagctct ctattggcct ctcaaccaaa aggtgttcct ctttaagggc      900

tccgggtact ggcagtggga cgagctagcc cgaactgact tcagcagcta ccccaaacca      960

atcaagggtt tgtttacggg agtgccaaac cagccctcgg ctgctatgag ttggcaagat     1020

ggccgagtct acttcttcaa gggcaaagtc tactggcgcc tcaaccagca gcttcgagta     1080

gagaaaggct atcccagaaa tatttcccac aactggatgc actgtcgtcc ccggactata     1140

gacactaccc catcaggtgg gaataccact ccctcaggta cgggcataac cttggatacc     1200

actctctcag ccacagaaac cacgtttgaa tac                                  1233


<210>  5926
<211>  852
<212>  DNA
<213>  Homo Sapiens

<400>  5926
caggaaactg actccgtggt cagctccgtt acgaccaagg tcaagggcgt ggctgtgacc       60

aacacttcta aacttggatt ccggatctgg gatgtggcgg attatgtgat accagctcag      120

gaggaaaact ccctcttcgt catgaccaac gtgatcctca ccatgaacca gacacagggc      180

ctgtgccccg agattccaga tgcgaccact gtgtgtaaat cagatgccag ctgtactgcc      240

ggctctgccg gcacccacag caacggagtc tcaacaggca ggtgcgtagc tttcaacggg      300

tccgtcaaga cgtgtgaggt ggcggcctgg tgcccggtgg aggatgacac acacgtgcca      360

caacctgctt ttttaaaggc tgcagaaaac ttcactcttt tggttaagaa caacatctgg      420

tatcccaaat ttaatttcag caagaggaat atccttccca acatcaccac tacttacctc      480

aagtcgtgca tttatgatgc taaaacagat cccttctgcc ccatattccg tcttggcaaa      540

atagtggaga acgcaggaca cggtttccag gacatggccg tggagggagg catcatgggc      600

atccaggtca actgggactg caacctggac agagccgcct ccctctgctt gcccaggtac      660

tccttccgcc gcctcgatac acgggacgtt gagcacaacg tatctcctgg ctacaatttc      720

aggtttgcca agtactacag agacctggct ggcaacgagc agcgcacgct catcaaggcc      780

tatggcatcc gcttcgacat cattgtgttt gggaaggcag ggaaatttga catcatcccc      840

actatgatca ac                                                          852


<210>  5927
<211>  864
<212>  DNA
<213>  Homo Sapiens

<400>  5927
agtgacaagc tgtaccagcg gaaagagcct gtcatcagtt ctgtgcacac caaggtgaag       60

gggatagcag aggtgaaaga ggagatcgtg gagaatggag tgaagaagtt ggtgcacagt      120

gtctttgaca ccgcagacta caccttccct ttgcagggga actctttctt cgtgatgaca      180

aactttctca aaacagaagg ccaagagcag cggttgtgtc ccgagtatcc cacccgcagg      240

acgctctgtt cctctgaccg aggttgtaaa aagggatgga tggacccgca gagcaaagga      300

attcagaccg gaaggtgtgt agtgcatgaa gggaaccaga agacctgtga agtctctgcc      360

tggtgcccca tcgaggcagt ggaagaggcc ccccggcctg ctctcttgaa cagtgccgaa      420

aacttcactg tgctcatcaa gaacaatatc gacttccccg gccacaacta caccacgaga      480

aacatcctgc caggtttaaa catcacttgt accttccaca agactcagaa tccacagtgt      540

cccattttcc gactaggaga catcttccga gaaacaggcg ataatttttc agatgtggca      600

attcagggcg gaataatggg cattgagatc tactgggact gcaacctaga ccgttggttc      660

catcactgcc atcccaaata cagtttccgt cgccttgacg acaagaccac caacgtgtcc      720

ttgtaccctg gctacaactt cagatacgcc aagtactaca aggaaaacaa tgttgagaaa      780

cggactctga taaaagtctt cgggatccgt tttgacatcc tggtttttgg caccggagga      840

aaatttgaca ttatccagct ggtt                                             864


<210>  5928
<211>  294
<212>  DNA
<213>  Homo Sapiens

<400>  5928
atggcagcag aaccactgac agagctagag gagtccattg agaccgtggt caccaccttc       60

ttcacctttg caaggcagga gggccggaag gatagcctca gcgtcaacga gttcaaagag      120

ctggttaccc agcagttgcc ccatctgctc aaggatgtgg gctctcttga tgagaagatg      180

aagagcttgg atgtgaatca ggactcggag ctcaagttca atgagtactg gagattgatt      240

ggggagctgg ccaaggaaat caggaagaag aaagacctga agatcaggaa gaag            294


<210>  5929
<211>  846
<212>  DNA
<213>  Homo Sapiens

<400>  5929
gccccaaagg atggagtcac aaggccagac tctgaagtgc agcatcagct cctgcccaac       60

cccttccagc caggccagga gcagctcgga cttctgcaga gctacctaaa gggactagga      120

aggacagaag tgcaactgga gcatctgagc cgggagcagg ttctcctcta cctctttgcc      180

ctccatgact atgaccagag tggacagctg gatggcctgg agctgctgtc catgttgaca      240

gctgctctgg cccctggagc tgccaactct cctaccacca acccggtgat attgatagtg      300

gacaaagtgc tcgagacgca ggacctgaat ggggatgggc tcatgacccc tgctgagctc      360

atcaacttcc cgggagtagc cctcaggcac gtggagcccg gagagcccct tgctccatct      420

cctcaggagc cacaagctgt tggaaggcag tccctattag ctaaaagccc attaagacaa      480

gaaacacagg aagcccctgg tcccagagaa gaagcaaagg gccaggtaga ggccagaagg      540

gagtctttgg atcctgtcca ggagcctggg ggccaggcag aggctgatgg agatgttcca      600

gggcccagag gggaagctga gggccaggca gaggctaaag gagatgcccc tgggcccaga      660

ggggaagctg ggggccaggc agaggctgaa ggagatgccc ccgggcccag aggggaagct      720

gggggccagg cagaggccag ggagaatgga gaggaggcca aggaacttcc aggggaaaca      780

ctggagtcta agaacaccca aaatgacttt gaggtgcaca ttgttcaagt ggagaatgat      840

gagatc                                                                 846


<210>  5930
<211>  585
<212>  DNA
<213>  Homo Sapiens

<400>  5930
tgcagctgcg ccccggcgca ccctcagcag cacatctgcc actcggcact tgtgattcgg       60

gccaaaatct ccagtgagaa ggtagttccg gccagtgcag accctgctga cactgaaaaa      120

atgctccggt atgaaatcaa acagataaag atgttcaaag ggtttgagaa agtcaaggat      180

gttcagtata tctatacgcc ttttgactct tccctctgtg gtgtgaaact agaagccaac      240

agccagaagc agtatctctt gactggtcag gtcctcagtg atggaaaagt cttcatccat      300

ctgtgcaact acatcgagcc ctgggaggac ctgtccttgg tgcagaggga aagtctgaat      360

catcactacc atctgaactg tggctgccaa atcaccacct gctacacagt accctgtacc      420

atctcggccc ctaacgagtg cctctggaca gactggctgt tggaacgaaa gctctatggt      480

taccaggctc agcattatgt ctgtatgaag catgttgacg gcacctgcag ctggtaccgg      540

ggccacctgc ctctcaggaa ggagtttgtt gacatcgttc agccc                      585


<210>  5931
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  5931
ctgcccacca accctgagga gagctggcag gtgtacagct ctgcccagga cagcgagggc       60

aggtgtatct gcacagtggt cgccccacag cagaccatgt gttcacggga tgcccgcaca      120

aaacagctga ggcagctact ggagaaggtg cagaacatgt ctcaatccat agaggtcttg      180

gacaggcgga cccagagaga cttgcagtac gtggagaaga tggagaacca aatgaaagga      240

ctggagtcca agttcaaaca ggtggaggag agtcataagc aacacctggc caggcagttt      300

aaggcgataa aagcgaaaat ggatgaactt aggcctttga tacctgtgtt ggaagagtac      360

aaggccgatg ccaaattggt attgcagttt aaagaggagg tccagaatct gacgtcagtg      420

cttaacgagc tgcaagagga aattggcgcc tatgactacg atgaacttca gagcagagtg      480

tccaatcttg aagaaaggct ccgtgcatgc atgcaaaaac tagcttgcgg gaagttgacg      540

ggcatcagtg accccgtgac tgtcaagacc tccggctcga ggttcggatc ctggatgaca      600

gaccctctcg cccctgaagg cgataaccgg gtgtggtaca tggacggcta tcacaacaac      660

cgcttcgtac gtgagtacaa gtccatggtt gacttcatga acacggacaa tttcacctcc      720

caccgtctcc cccacccctg gtcgggcacg gggcaggtgg tctacaacgg ttctatctac      780

ttcaacaagt tccagagcca catcatcatc aggtttgacc tgaagacaga gaccatcctc      840

aagacccgca gcctggacta tgccggttac aacaacatgt accactacgc ctggggtggc      900

cactcggaca tcgacctcat ggtggacgag agcgggctgt gggccgtgta cgccaccaac      960

cagaacgctg gcaacatcgt ggtcagtagg ctggaccccg tgtccctgca gaccctgcag     1020

acctggaaca cgagctaccc caagcgcagc gccggggagg ccttcatcat ctgcggcacg     1080

ctgtacgtca ccaacggcta ctcagggggt accaaggtcc actatgcata ccagaccaat     1140

gcctccacct atgaatacat cgacatccca ttccagaaca aatactccca catctccatg     1200

ctggactaca accccaagga ccgggccctg tatgcctgga acaacggcca ccagatcctc     1260

tacaacgtga ccctcttcca cgtcatccgc tccgacgagt tg                        1302


<210>  5932
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  5932
cggggggcgg cctcgagcgg gaacgcgacc gggcctgggc ctcggagcgc gggcgggagc       60

gcgaggagga gcgcggcggt gactggccct ccgccgccgc tgagccactg cggccgggct      120

gccccctgcg agccgctgcg ctacaacgtg tgcctgggct cggtgctgcc ctacggggcc      180

acctccacac tgctggccgg agactcggac tcccaggagg aagcgcacgg caagctcgtg      240

ctctggtcgg gcctccggaa tgccccccgc tgctgggcag tgatccagcc cctgctgtgt      300

gccgtataca tgcccaagtg tgagaatgac cgggtggagc tgcccagccg taccctctgc      360

caggccaccc gaggcccctg tgccatcgtg gagagggagc ggggctggcc tgacttcctg      420

cgctgcactc ctgaccgctt ccctgaaggc tgcacgaatg aggtgcagaa catcaagttc      480

aacagttcag gccagtgcga agtgcccttg gttcggacag acaaccccaa gagctggtac      540

gaggacgtgg agggctgcgg catccagtgc cagaacccgc tcttcacaga ggctgagcac      600

caggacatgc acagctac                                                    618


<210>  5933
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5933
gcctacgtgc tcttctacct cttcgcctcc ctcaccagcg acctaccctg ggagcactgt       60

ggcaactggt ggaacacaga actctgcctg gagcacagag tctccaagga cggcaacggg      120

gccctgcccc tcaacctcac ctgcaccgtc agccccagcg aggagtactg gagccgctac      180

gtcctccaca tccaaggcag ccagggcatc ggcagccctg gggagatccg c               231


<210>  5934
<211>  717
<212>  DNA
<213>  Homo Sapiens

<400>  5934
gtggtgggag gagaggatgc ccggccccac agctggccct ggcagatctc cctccagtac       60

ctcaagaacg acacgtggag gcatacgtgt ggcgggactt tgattgctag caacttcgtc      120

ctcactgccg cccactgcat cagcaacacc cggacctacc gtgtggccgt gggaaagaac      180

aacctggagg tggaagacga agaaggatcc ctgtttgtgg gtgtggacac catccacgtc      240

cacaagagat ggaatgccct cctgttgcgc aatgatattg ccctcatcaa gcttgcagag      300

catgtggagc tgagtgacac catccaggtg gcctgcctgc cagagaagga ctccctgctc      360

cccaaggact acccctgcta tgtcaccggc tggggccgcc tctggaccaa cggccccatt      420

gctgataagc tgcagcaggg cctgcagccc gtggtggatc acgccacgtg ctccaggatt      480

gactggtggg gcttcagggt gaagaaaacc atggtgtgcg ctgggggcga tggcgtcatc      540

tcagcctgca atggggactc cggtggccca ctgaactgcc agttggagaa cggttcctgg      600

gaggtgtttg gcatcgtcag ctttggctcc cggcggggct gcaacacccg caagaagccg      660

gtagtctaca cccgggtgtc cgcctacatc gactggatca acgagaaaat gcagctg         717


<210>  5935
<211>  207
<212>  DNA
<213>  Homo Sapiens

<400>  5935
cgaggacgca acgtcgagaa catgaagatc ttgcgtctaa tgctgctcca catcaaatac       60

ctgtacggga tccgagtgga ggtgcgaggg gctcaccact tccctccctc gcagccctat      120

gttgttgtct ccaaccacca gagctctctc gatctgcttg ggatgatgga ggtactgcca      180

ggccgctgtg tgcccattgc caagcgc                                          207


<210>  5936
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  5936
caaagaggcc ccaggggacc atatccacct ggaccactgg ctcctcctcc tccaccacgt       60

tttccttttg gaacaggatt tgttccacca ccccatcctc caccctatgg tccagggaga      120

tttccaccac ccctttctcc accctatggt ccagggagaa tcccaccatc ccctcctcca      180

ccctatggtc cagggagaat tcaatcacac tctcttcctc ctccttatgg cccaggttat      240

ccacagccac cttcccaacc aagaccctat ccacctggac ctccattttt ccctgtaaat      300

tctccaactg atcctgccct ccctactctt gcaccc                                336


<210>  5937
<211>  411
<212>  DNA
<213>  Homo Sapiens

<400>  5937
gagctcacgg aagcccagcg ccggggcctg caggtggccc tggaggaatt tcacaagcac       60

ccgcccgtgc agtgggcctt ccaggagacc agtgtggaga gcgccgtgga cacgcccttc      120

ccagctggaa tatttgtgag gctggaattt aagctgcagc agacaagctg ccggaagagg      180

gactggaaga aacccgagtg caaagtcagg cccaatggga ggaaacggaa atgcctggcc      240

tgcatcaaac tgggctctga ggacaaagtt ctgggccggt tggtccactg ccccatagag      300

acccaagttc tgcgggaggc tgaggagcac caggagaccc agtgcctcag ggtgcagcgg      360

gctggtgagg acccccacag cttctacttc cctggacagt tcgccttctc c               411


<210>  5938
<211>  1416
<212>  DNA
<213>  Homo Sapiens

<400>  5938
aggacagctc agctcaggaa ggccaatgac cagagtggcc gatgccagta taccttcagt       60

gtggccagtc ccaatgaatc cagctgccca gagcagagcc aggccatgtc agtcatccat      120

aacttacaga gagacagcag cacccaacgc ttagacctgg aggccaccaa agctcgactc      180

agctccctgg agagcctcct ccaccaattg accttggacc aggctgccag gccccaggag      240

acccaggagg ggctgcagag ggagctgggc accctgaggc gggagcggga ccagctggaa      300

acccaaacca gagagttgga gactgcctac agcaacctcc tccgagacaa gtcagttctg      360

gaggaagaga agaagcgact aaggcaagaa aatgagaatc tggccaggag gttggaaagc      420

agcagccagg aggtagcaag gctgagaagg ggccagtgtc cccagacccg agacactgct      480

cgggctgtgc caccaggctc cagagaagtt tctacgtgga atttggacac tttggccttc      540

caggaactga agtccgagct aactgaagtt cctgcttccc gaattttgaa ggagagccca      600

tctggctatc tcaggagtgg agagggagac accggatgtg gagaactagt ttgggtagga      660

gagcctctca cgctgagaac agcagaaaca attactggca agtatggtgt gtggatgcga      720

gaccccaagc ccacctaccc ctacacccag gagaccacgt ggagaatcga cacagttggc      780

acggatgtcc gccaggtttt tgagtatgac ctcatcagcc agtttatgca gggctaccct      840

tctaaggttc acatactgcc taggccactg gaaagcacgg gtgctgtggt gtactcgggg      900

agcctctatt tccagggcgc tgagtccaga actgtcataa gatatgagct gaataccgag      960

acagtgaagg ctgagaagga aatccctgga gctggctacc acggacagtt cccgtattct     1020

tggggtggct acacggacat tgacttggct gtggatgaag caggcctctg ggtcatttac     1080

agcaccgatg aggccaaagg tgccattgtc ctctccaaac tgaacccaga gaatctggaa     1140

ctcgaacaaa cctgggagac aaacatccgt aagcagtcag tcgccaatgc cttcatcatc     1200

tgtggcacct tgtacaccgt cagcagctac acctcagcag atgctaccgt caactttgct     1260

tatgacacag gcacaggtat cagcaagacc ctgaccatcc cattcaagaa ccgctataag     1320

tacagcagca tgattgacta caaccccctg gagaagaagc tctttgcctg ggacaacttg     1380

aacatggtca cttatgacat caagctctcc aagatg                               1416


<210>  5939
<211>  990
<212>  DNA
<213>  Homo Sapiens

<400>  5939
ggctggacag tggctggaca gttccaagaa aagaaacgct tcactgaaga agtcattgaa       60

tacttccaga agaaagttag cccagtgcat ctgaaaatcc tgctgactag cgatgaagcc      120

tggaagagat ttgtgcgtgt ggctgaattg cccagggaag aggcagatgc tctctatgaa      180

gctctgaaga atcttacacc atatgtggct attgaggaca aagacatgca gcaaaaagaa      240

cagcagttta gggagtggtt tttgaaagag tttcctcaaa tcagatggaa gattcaggag      300

tccatagaaa ggcttcgtgt cattgcaaat gagattgaaa aggtccacag aggctgcgtc      360

atcgccaatg tggtgtctgg ctccactggc atcctgtctg tcattggcgt tatgttggca      420

ccatttacag cagggctgag cctgagcatt actgcagctg gggtagggct gggaatagca      480

tctgccacgg ctgggatcgc ctccagcatc gtggagaaca catacacaag gtcagcagaa      540

ctcacagcca gcaggctgac tgcaaccagc actgaccaat tggaggcatt aagggacatt      600

ctgcgtgaca tcacacccaa tgtgctttct tttgcacttg attttgacga agccacaaaa      660

atgattgcga atgatgtcca tacactcagg agatctaaag ccactgttgg acgccctttg      720

attgcttggc gatatgtacc tataaatgtt gttgagacac tgagaacacg tggggccccc      780

acccggatag tgagaaaagt agcccggaac ctgggcaagg ccacttcagg tgtccttgtt      840

gtgctggatg tagtcaacct tgtgcaagac tcactggact tgcacaaggg ggcaaaatcc      900

gagtctgctg agtcgctgag gcagtgggct caggagctgg aggagaatct caatgagctc      960

acccatatcc atcagagtct aaaagcaggc                                       990


<210>  5940
<211>  264
<212>  DNA
<213>  Homo Sapiens

<400>  5940
cagtgttcct tagactccgt tatggataag aagatcaagg atgttctcaa cagtctagag       60

tacagtccct ctcctataag caagaagctc tcgtgtgcta gtgtcaaaag ccaaggcaga      120

ccgtcctcct gccctgctgg gatggctgtc actggctgtg cttgtggcta tggctgtggt      180

tcgtgggatg ttcagctgga aaccacctgc cactgccagt gcagtgtggt ggactggacc      240

actgcccgct gctgccacct gacc                                             264


<210>  5941
<211>  1236
<212>  DNA
<213>  Homo Sapiens

<400>  5941
gctgccgcgg cggtggctgc agccgggggg cggtcggacg gcggtaattt tctggatgat       60

aaacaatggc tcaccacaat ctctcagtat gacaaggaag tcggacagtg gaacaaattc      120

cgagacgatg attatttccg cacttggagt ccaggaaaac ccttcgatca ggctttagat      180

ccagctaagg atccatgctt aaagatgaaa tgtagtcgcc ataaagtatg cattgctcaa      240

gattctcaga ctgcagtctg cattagtcac cggaggctta cacacaggat gaaagaagca      300

ggagtagacc ataggcagtg gaggggtccc atattatcca cctgcaagca gtgcccagtg      360

gtctatccca gccctgtttg tggttcagat ggtcatacct actcttttca gtgcaaacta      420

gaatatcagg catgtgtctt aggaaaacag atctcagtca aatgtgaagg acattgccca      480

tgtccttcag ataagcccac cagtacaagc agaaatgtta agagagcatg cagtgacctg      540

gagttcaggg aagtggcaaa cagattgcgg gactggttca aggcccttca tgaaagtgga      600

agtcaaaaca agaagacaaa aacattgctg aggcctgaga gaagcagatt cgataccagc      660

atcttgccaa tttgcaagga ctcacttggc tggatgttta acagacttga tacaaactat      720

gacctgctat tggaccagtc agagctcaga agcatttacc ttgataagaa tgaacagtgt      780

accaaggcat tcttcaattc ttgtgacaca tacaaggaca gtttaatatc taataatgag      840

tggtgctact gcttccagag acagcaagac ccaccttgcc agactgagct cagcaatatt      900

cagaagcggc aaggggtaaa gaagctccta ggacagtata tccccctgtg tgatgaagat      960

ggttactaca agccaacaca atgtcatggc agtgttggac agtgctggtg tgttgacaga     1020

tatggaaatg aagtcatggg atccagaata aatggtgttg cagattgtgc tatagatttt     1080

gagatctccg gagattttgc tagtggcgat tttcatgaat ggactgatga tgaggatgat     1140

gaagacgata ttatgaatga tgaagatgaa attgaagatg atgatgaaga tgaaggggat     1200

gatgatgatg gtggtgatga ccatgatgta tacatt                               1236


<210>  5942
<211>  570
<212>  DNA
<213>  Homo Sapiens

<400>  5942
caggggtggc aggcgttcaa gaatgatgcc acggaaatca tccccgagct cggagagtac       60

cccgagcctc caccggagct ggagaacaac aagaccatga accgggcgga gaacggaggg      120

cggcctcccc accacccctt tgagaccaaa gacgtgtccg agtacagctg ccgcgagctg      180

cacttcaccc gctacgtgac cgatgggccg tgccgcagcg ccaagccggt caccgagctg      240

gtgtgctccg gccagtgcgg cccggcgcgc ctgctgccca acgccatcgg ccgcggcaag      300

tggtggcgac ctagtgggcc cgacttccgc tgcatccccg accgctaccg cgcgcagcgc      360

gtgcagctgc tgtgtcccgg tggtgaggcg ccgcgcgcgc gcaaggtgcg cctggtggcc      420

tcgtgcaagt gcaagcgcct cacccgcttc cacaaccagt cggagctcaa ggacttcggg      480

accgaggccg ctcggccgca gaagggccgg aagccgcggc cccgcgcccg gagcgccaaa      540

gccaaccagg ccgagctgga gaacgcctac                                       570


<210>  5943
<211>  557
<212>  DNA
<213>  Homo Sapiens

<400>  5943
tgccagctgc cctccgagtg gaggcccctg agcgagggct gccgcgccga gctggccgag       60

accatcgtgt acgccagggt gctggcgctg caccccgagg cgcccggcct ctacaaccac      120

ctgccctggc agtaccacgc cggccagggg ggcctcttct actcggccga ggtcgagatg      180

ctgtgcgacc aggcgtgggg cagcatgctg gaggtgcccg ccggctccag gctcaacctc      240

accggcctgg gctacttctc gtgccactcc cacaccgtgg tccaggacta ctcctatttc      300

ttcttcctca ggatggatga aaattataac ctcttgcctc acggagtcaa tttccaagat      360

gccatcttcc cagacactca agagaacaga aggatgtttt ctagcctttt ccagttttca      420

aactgttcgc aagggcagca gctggcgact ttctccagtg actgggaaat ccaggaagac      480

agtaggctca tgtgctcctc ggtgcagaag gccttgtttg aggaggagga ccacgtcaag      540

aaactgcagc agaaagt                                                     557


<210>  5944
<211>  3261
<212>  DNA
<213>  Homo Sapiens

<400>  5944
gccactcgag tctactacct gggcatccgg gatgtgcagt ggaactatgc tcccaaggga       60

agaaatgtca tcacgaacca gcctctggac agtgacatag tggcttccag cttcttaaag      120

tctgacaaga accggatagg gggaacctac aagaagacca tctataaaga atacaaggat      180

gactcataca cagatgaagt ggcccagcct gcctggttgg gcttcctggg gccagtgttg      240

caggctgaag tgggggatgt cattcttatt cacctgaaga attttgccac tcgtccctat      300

accatccacc ctcatggtgt cttctacgag aaggactctg aaggttccct atacccagat      360

ggctcctctg ggccactgaa agctgatgac tctgttcccc cggggggcag ccatatctac      420

aactggacca ttccagaagg ccatgcaccc accgatgctg acccagcgtg cctcacctgg      480

atctaccatt ctcatgtaga tgctccacga gacattgcaa ctggcctaat tgggcctctc      540

atcacctgta aaagaggagc cctggatggg aactcccctc ctcaacgcca ggatgtagac      600

catgatttct tcctcctctt cagtgtggta gatgagaacc tcagctggca tctcaatgag      660

aacattgcca cttactgctc agatcctgct tcagtggaca aagaagatga gacatttcag      720

gagagcaata ggatgcatgc aatcaatggc tttgtttttg ggaatttacc tgagctgaac      780

atgtgtgcac agaaacgtgt ggcctggcac ttgtttggca tgggcaatga aattgatgtc      840

cacacagcat ttttccatgg acagatgctg actacccgtg gacaccacac tgatgtggct      900

aacatctttc cagccacctt tgtgactgct gagatggtgc cctgggaacc tggtacctgg      960

ttaattagct gccaagtgaa cagtcacttt cgagatggca tgcaggcact ctacaaggtc     1020

aagtcttgct ccatggcccc tcctgtggac ctgctcacag gcaaagttcg acagtacttc     1080

attgaggccc atgagattca atgggactat ggcccgatgg ggcatgatgg gagtactggg     1140

aagaatttga gagagccagg cagtatctca gataagtttt tccagaagag ctccagccga     1200

attgggggca cttactggaa agtgcgatat gaagcctttc aagatgagac attccaagag     1260

aagatgcatt tggaggaaga taggcatctt ggaatcctgg ggccagtgat ccgggctgag     1320

gtgggtgaca ccattcaggt ggtcttctac aaccgtgcct cccagccatt cagcatgcag     1380

ccccatgggg tcttttatga gaaagactat gaaggcactg tgtacaatga tggctcatct     1440

taccctggct tggttgccaa gccctttgag aaagtaacat accgctggac agtcccccct     1500

catgccggtc ccactgctca ggatcctgct tgtctcactt ggatgtactt ctctgctgca     1560

gatcccataa gagacacaaa ttctggcctg gtgggcccgc tgctggtgtg cagggctggt     1620

gccttgggtg cagatggcaa gcagaaaggg gtggataaag aattctttct tctcttcact     1680

gtgttggatg agaacaagag ctggtacagc aatgccaatc aagcagctgc tatgttggat     1740

ttccgactgc tttcagagga tattgagggc ttccaagact ccaatcggat gcatgccatt     1800

aatgggtttc tgttctctaa cctgcccagg ctggacatgt gcaagggtga cacagtggcc     1860

tggcacctgc tcggcctggg cacagagact gatgtgcatg gagtcatgtt ccagggcaac     1920

actgtgcagc ttcagggcat gaggaagggt gcagctatgc tctttcctca tacctttgtc     1980

atggccatca tgcagcctga caaccttggg acatttgaga tttattgcca ggcaggcagc     2040

catcgagaag cagggatgag ggcaatctat aatgtctccc agtgtcctgg ccaccaagcc     2100

acccctcgcc aacgctacca agctgcaaga atctactata tcatggcaga agaagtagag     2160

tgggactatt gccctgaccg gagctgggaa cgggaatggc acaaccagtc tgagaaggac     2220

agttatggtt acattttcct gagcaacaag gatgggctcc tgggttccag atacaagaaa     2280

gctgtattca gggaatacac tgatggtaca ttcaggatcc ctcggccaag gactggacca     2340

gaagaacact tgggaatctt gggtccactt atcaaaggtg aagttggtga tatcctgact     2400

gtggtattca agaataatgc cagccgcccc tactctgtgc atgctcatgg agtgctagaa     2460

tctactactg tctggccact ggctgctgag cctggtgagg tggtcactta tcagtggaac     2520

atcccagaga ggtctggccc tgggcccaat gactctgctt gtgtttcctg gatctattat     2580

tctgcagtgg atcccatcaa ggacatgtat agtggcctgg tggggccctt ggctatctgc     2640

caaaagggca tcctggagcc ccatggagga cggagtgaca tggatcggga atttgcattg     2700

ttgttcttga tttttgatga aaataagtct tggtatttgg aggaaaatgt ggcaacccat     2760

gggtcccagg atccaggcag tattaaccta caggatgaaa ctttcttgga gagcaataaa     2820

atgcatgcaa tcaatgggaa actctatgcc aaccttaggg gtcttaccat gtaccaagga     2880

gaacgagtgg cctggtacat gctggccatg ggccaagatg tggatctaca caccatccac     2940

tttcatgcag agagcttcct ctatcggaat ggcgagaact accgggcaga tgtggtggat     3000

ctgttcccag ggacttttga ggttgtggag atggtggcca gcaaccctgg gacatggctg     3060

atgcactgcc atgtgactga ccatgtccat gctggcatgg agaccctctt cactgttttt     3120

tctcgaacag aacacttaag ccctctcacc gtcatcacca aagagactga aaaagcagtg     3180

ccccccagag acattgaaga aggcaatgtg aagatgctgg gcatgcagat ccccataaag     3240

aatgttgaga tgctggcctc t                                               3261


<210>  5945
<211>  2484
<212>  DNA
<213>  Homo Sapiens

<400>  5945
aacaaagcca acaagcacaa gccatggatt gaggcagagt accagggcat cgtcatggag       60

aatgacaaca cggtcctact gaatccacca ctctttgcct tggacaagga tgccccgctg      120

cgctatgcag gtgagatctg cggcttccgg ctccatgggt ctggggtgcc ctttgaggct      180

gtgatccttg acaaggcgac aggagagggg ctgatccggg ccaaggagcc tgtggactgc      240

gaggcccaga aggaacacac cttcaccatc caggcctatg actgtggcga gggccccgac      300

ggggccaaca ccaagaagtc ccacaaggcc actgtgcatg tgcgggtcaa cgatgtgaac      360

gagtttgccc cagtgtttgt ggaacggctg tatcgtgcgg ctgtgacaga ggggaagctg      420

tacgatcgca tcctgcgggt ggaagccatt gacggtgact gctcccccca gtacagccag      480

atctgctact atgagattct cacacccaac acccctttcc tcattgacaa tgacgggaac      540

attgagaaca cagagaagct gcagtacagt ggtgagaggc tctataagtt tacagtgaca      600

gcttatgact gtgggaagaa gcgggcagca gatgatgctg aggtggagat tcaggtgaag      660

cccacctgta aacccagctg gcaaggctgg aacaaaagga tcgaatatgc accaggtgct      720

gggagcttgg ctttgttccc tggtatccgc ctggagacct gtgatgaacc actctggaac      780

attcaggcca ccatagagct gcagaccagc catgtggcca agggctgtga ccgtgacaac      840

tactcagagc gggcgctgcg gaaactctgt ggtgctgcca ctggggaggt ggatctgttg      900

cccatgcctg gccccaatgc caactggaca gcaggactct cggtgcacta cagccaggac      960

agcagcctga tctactggtt caatggcacc caggctgtgc aggtgcccct gggtggcccc     1020

agtgggctgg gctctgggcc ccaggacagc ctcagtgacc acttcaccct gtccttctgg     1080

atgaagcatg gcgtaactcc caacaagggc aagaaggaag aggaaaccat cgtatgtaac     1140

actgtccaga atgaggacgg cttctctcac tactcgctga ctgtccacgg ctgtaggatt     1200

gccttcctct actggcccct gcttgagagt gcccgcccag tcaagttcct ctggaagctg     1260

gagcaggtct gtgatgatga gtggcaccac tacgctctga acctcgagtt ccccacagtc     1320

acactctata ccgacggcat ctccttcgac cctgccctca tccatgacaa tggcctcatc     1380

cacccacccc gaagggagcc tgctctcatg attggggcct gctggactga ggagaagaac     1440

aaagagaagg aaaagggaga caacagtaca gacaccaccc aaggagaccc tttgtcgatc     1500

caccactact tccatggcta cctggctggt ttcagcgtgc gctcaggtcg cctggagagc     1560

cgcgaggtca tcgagtgcct ctatgcatgt cgggaggggc tggactatag ggatttcgag     1620

agcctgggca aaggcatgaa ggtccacgtg aacccctcac agtccctgct caccctggag     1680

ggggatgatg tggagacctt caaccatgcc ctgcagcatg tggcttacat gaacactctg     1740

cgctttgcca cgcccggcgt caggcccctg cgcctcacca ctgctgtcaa gtgcttcagc     1800

gaagagtcct gcgtctccat ccctgaagtg gagggctacg tggtcgtcct tcagcctgac     1860

gccccccaga tcctgctgag tggcactgct cattttgccc gcccagctgt ggactttgag     1920

ggaaccaacg gcgtcccttt gttccctgat cttcaaatca cctgctccat ttctcaccag     1980

gtggaggcca aaaaggatga gagttggcag ggcacagtga cagacacacg catgtcggat     2040

gagattgtgc acaacctgga tggctgtgaa atttctctgg tgggggatga cctggatccc     2100

gagcgggaaa gcctgctcct ggacacaacc tctctgcagc agcgggggct ggagctcacc     2160

aacacatctg cctacctcac tattgctggg gtggagagca tcactgtgta tgaagagatc     2220

ctgaggcagg ctcgttatcg gctgcgacac ggagctgccc tctacaccag gaagttccgg     2280

ctttcctgct cggaaatgaa tggccgttac tccagcaatg aattcatcgt ggaggtcaat     2340

gtcctgcaca gcatgaaccg ggttgcccac cccagccacg tgctcagctc ccagcagttc     2400

ctgcaccgtg gtcaccagcc cccgcctgag atggctggac acagcctagc cagctcccac     2460

agaaactcca tgatacccag cgcc                                            2484


<210>  5946
<211>  183
<212>  DNA
<213>  Homo Sapiens

<400>  5946
gaaggcatcc ttggcaagcc gtgtcccaaa atcaaagtgg aatgcgaagt ggaagaaata       60

gaccagtgta ccaaacccag agattgccca gaaaacatga agtgttgccc gttcagccgt      120

ggaaagaaat gtttagactt cagaaaggtc agccttactt tataccataa ggaggagctt      180

gaa                                                                    183


<210>  5947
<211>  978
<212>  DNA
<213>  Homo Sapiens

<400>  5947
cggcctgcca accactcgtc cactcgagag agagtagcca acagggagga gaatgagatc       60

ctgcccccag accacctgaa cggggtgaag ctggagatgg acgggcacct caatcgcggc      120

ttccaccagg aggtcttcct aggcaaggac ctgggtggct ttgatgagga cgcggagccg      180

cggcggagcc ggaggaagct gatggtcatc ttttccaagg tggatgtgaa cactgaccgg      240

aagatcagtg ccaaggagat gcagcgctgg atcatggaga agacggccga gcacttccag      300

gaggccatgg aggagagcaa gacacacttc cgcgccgtgg accctgacgg ggacggtcac      360

gtgtcttggg acgagtataa ggtgaagttt ttggcgagta aaggccatag cgagaaggag      420

gttgccgacg ccatcaggct caacgaggaa ctcaaagtgg acgaggaaac acaggaagtc      480

ctggagaacc tgaaggaccg ctggtaccag gcggacagcc cccctgcaga cctgctgctg      540

acggaggagg agttcctgtc gttcctccac cccgagcaca gccggggaat gctcaggttc      600

atggtgaagg agatcgtccg ggacctggac caggacggtg acaagcagct ctctgtgccc      660

gagttcatct ccctgcccgt gggcaccgtg gagaaccagc agggccagga cattgacgac      720

aactgggtga aagacagaaa aaaggagttt gaggagctca ttgactccaa ccacgacggc      780

atcgtgaccg ccgaggagct ggagagctac atggacccca tgaacgagta caacgcgctg      840

aacgaggcca agcagatgat cgccgtcgcc gacgagaacc agaaccacca cctggagccc      900

gaggaggtgc tcaagtacag cgagttcttc acgggcagca agctggtgga ctacgcgcgc      960

agcgtgcacg aggagttt                                                    978


<210>  5948
<211>  450
<212>  DNA
<213>  Homo Sapiens

<400>  5948
ggtgagcaat cgcaggcgct ggctcagtca ataaaggatc cgggcccaac acgcacattc       60

acagtagttc ccagggcagc agaaagtact gaaatcccac cttatgtgat gaagtgtccg      120

agcaatggtt tgtgtagcag gcttcctgca gactgtatag actgcacaac aaatttctcc      180

tgtacctatg ggaagcctgt cacttttgac tgtgcagtga aaccatctgt tacctgtgtt      240

gatcaagact tcaaatccca aaagaacttc atcattaaca tgacttgcag attttgctgg      300

cagcttcctg aaacagatta cgagtgtacc aactccacca gctgcatgac ggtgtcctgt      360

cctcggcagc gctaccctgc caactgcacg gtgcgggacc acgtccactg cttgggtaac      420

cgtacttttc ccaaaatgct atattgcaat                                       450


<210>  5949
<211>  1425
<212>  DNA
<213>  Homo Sapiens

<400>  5949
ctggagccag agctgccagg ctcggcgctg cgctctctct ggagctcgct gtgtctgggg       60

cccgcgcctg cgcccccggg acccgtctcc cccgagggcc ggttggcggc agcctgggac      120

gcgcttatcg tgcggccagt ccggcgctgg cgccgcgtgg cagtgggagt caatgcatgt      180

gttgatgtgg tgctctcagg ggtgaagctc ttgcaggcac ttggccttag tcctgggaat      240

gggaaagatc acagcattct gcattcaagg aatgatctgg aagaagcctt cattcacttc      300

atggggaagg gagcagctgc tgagcgcttc ttcagtgata aggaaacttt tcacgacatt      360

gcccaggttg cgtcagagtt cccaggagcc cagcactatg taggaggaaa tgcagcttta      420

attggacaga aatttgcagc caactcagat ttaaaggttc ttctttgcgg tccagttggt      480

ccaaagctac atgagcttct tgatgacaat gtctttgttc caccagagtc attgcaggaa      540

gtggatgagt tccacctcat tttagagtat caagcagggg aggagtgggg ccagttaaaa      600

gctccccatg ccaaccgatt catcttctct cacgacctct ccaacggggc catgaatatg      660

ctggaggtgt ttgtgtctag cctggaggag tttcagccag acctggtggt cctctctgga      720

ttgcacatga tggagggaca aagcaaggag ctccagagga agagactctt ggaggttgta      780

acctccattt ctgacatccc cactggtatt ccagttcacc tagagctggc cagtatgact      840

aacagggagc tcatgagcag cattgtccat cagcaggtct ttcccgcggt gacttccctt      900

gggctgaatg aacaggagct gttatttctc acccagtcag cctctggacc tcactcttct      960

ctctcttcct ggaacggtgt tcctgatgtg ggcatggtca gtgacatcct cttctggatc     1020

ttgaaagaac atgggaggag taaaagcaga gcctcggatc tcaccaggat ccatttccac     1080

acgctggtct accacatcct ggcaactgtg gatggacact gggccaacca gctggcagcc     1140

gtggctgcag gagctcgtgt ggctgggaca caggcctgcg ccacagaaac catagacacc     1200

agccgagtgt ctctgagggc accccaagag ttcatgactt cccattcgga ggcaggctcc     1260

aggattgtat taaacccaaa caagccagta gtagaatggc acagagaggg aatatccttc     1320

cacttcacac cagtattggt gtgtaaagac cccattcgaa ctgtaggcct tggagatgcc     1380

atttcagccg aaggactctt ctattcggaa gtacaccctc actat                     1425


<210>  5950
<211>  1131
<212>  DNA
<213>  Homo Sapiens

<400>  5950
gaaataacaa gtcttgatac agagaatata gatgaaattt taaacaatgc tgatgttgct       60

ttagtaaatt tttatgctga ctggtgtcgt ttcagtcaga tgttgcatcc aatttttgag      120

gaagcttccg atgtcattaa ggaagaattt ccaaatgaaa atcaagtagt gtttgccaga      180

gttgattgtg atcagcactc tgacatagcc cagagataca ggataagcaa atacccaacc      240

ctcaaattgt ttcgtaatgg gatgatgatg aagagagaat acaggggtca gcgatcagtg      300

aaagcattgg cagattacat caggcaacaa aaaagtgacc ccattcaaga aattcgggac      360

ttagcagaaa tcaccactct tgatcgcagc aaaagaaata tcattggata ttttgagcaa      420

aaggactcgg acaactatag agtttttgaa cgagtagcga atattttgca tgatgactgt      480

gcctttcttt ctgcatttgg ggatgtttca aaaccggaaa gatatagtgg cgacaacata      540

atctacaaac caccagggca ttctgctccg gatatggtgt acttgggagc tatgacaaat      600

tttgatgtga cttacaattg gattcaagat aaatgtgttc ctcttgtccg agaaataaca      660

tttgaaaatg gagaggaatt gacagaagaa ggactgcctt ttctcatact ctttcacatg      720

aaagaagata cagaaagttt agaaatattc cagaatgaag tagctcggca attaataagt      780

gaaaaaggta caataaactt tttacatgcc gattgtgaca aatttagaca tcctcttctg      840

cacatacaga aaactccagc agattgtcct gtaatcgcta ttgacagctt taggcatatg      900

tatgtgtttg gagacttcaa agatgtatta attcctggaa aactcaagca attcgtattt      960

gacttacatt ctggaaaact gcacagagaa ttccatcatg gacctgaccc aactgataca     1020

gccccaggag agcaagccca agatgtagca agcagtccac ctgagagctc cttccagaaa     1080

ctagcaccca gtgaatatag gtatactcta ttgagggatc gagatgagct t              1131


<210>  5951
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  5951
gctgatggct ctgcggcagt ggccaccagt gacttctgtg tggctcctga caccttcatc       60

ctgaacgtca cggagggcca gatcagcaca gaggtgactc gctactacct gtattgcagc      120

cagagtggaa gcagcccctt ccagcagacc ctgaccacct tccagcgcgc acttaccacc      180

atgcagatcc aggtcgcggg gctgctgcag tttgccgtgc ccctcttctc cactgcagag      240

gaagacctgc ttgcaatcca gctcctgctg aactcctcag agtccagcct tcaccagctg      300

accgccatgg tggactgccg agggctgcac aaggattatc tggacgctct tgctggcatc      360

tgctacgacg gcctccaggg c                                                381


<210>  5952
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  5952
cacggcttcc gtatccatga ttatttgtac tttcaagtgc tgagtcctgg ggacattcga       60

tacatcttca cagccacacc tgccaaggac tttggtggta tctttcacac aaggtatgag      120

cagattcacc ttgtccccgc tgaacctcca gaggcctgcg gggaactcag caacggtttc      180

ttcatccagg accagattgc tctggtggag agggggggct gctccttcct ctccaagact      240

cgggtggtcc aggagcacgg cgggcgggcg gtgatcatct ctgacaacgc agttgacaat      300

gacagcttct acgtggagat gatccaggac agtacccagc gcacagctga catccccgcc      360

ctcttcctgc tcggccgaga cggctacatg atccgccgct ctctggaaca gcatgggctg      420

ccatgggcca tcatttccat cccagtcaat gtcaccagca tccccacctt tgagctgctg      480

caaccgccct ggaccttctg g                                                501


<210>  5953
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  5953
agccgcccac tccaagccag gtcccagcaa caccatgggc tggcagctga tctgggcaaa       60

ggcaagctgc acctggcagg accttgttgt ccctcagaga tggacacaac agagacatcg      120

ggccctggaa accatccaga acgctgtgga gtgccgagcc ctgaatgcga atccttcctg      180

gaacacctcc aacgtgccct tcgcagtcgc ttccgcctgc ggctattggg ggtacgccag      240

gcacagccgc tctgcgagga gctctgccag gcctggttcg ccaactgcga agatgatatc      300

acctgcggcc cgacttggct cccactctca gaaaaaaggg gctgtgagcc cagctgcctt      360

acctatggac agaccttcgc agacgggacg gacctttgtc gctcggctct gggccacgcc      420

ctaccggtgg ctgctcctgg agcccgtcac tgcttcaaca tctccatctc cgcggtacct      480

cgtcccagac caggacgacg gggccgggaa gctccctccc ggcgttcccg cagccctcgc      540

acctccatcc tggacgctgc gggcagcggg agtggcagtg gaagcggcag cggcccc         597


<210>  5954
<211>  1656
<212>  DNA
<213>  Homo Sapiens

<400>  5954
atgagtgata atccacccag aatggaagtg tgtccttact gtaagaagcc atttaaacga       60

ttaaaatccc acttgccata ctgtaagatg ataggaccaa ccatacctac tgatcaaaaa      120

gtttatcagt ccaagccagc tacactccca cgtgctaaaa agatgaaagg accaatcaaa      180

gatttaatta aagctaaagg gaaagagtta gagacagaga atgaagaaag aaattctaag      240

ttggtggtgg acaaaccaga acagacagtg aagacctttc cactgccagc tgttggtttg      300

gaaagagcag ctactacaaa ggcagataaa gacatcaaga atccaatcca accatccttc      360

aaaatgttaa aaaatactaa accaatgact actttccaag aagaaaccaa ggctcagttt      420

tacgcatcag agaaaacctc tcctaaaaga gaacttgcca aagatttgcc taaatcagga      480

gaaagtcgat gtaatccttc agaagctgga gcgtctttac tggttggctc aatagaacct      540

tctttgtcaa atcaagatag aaaatattcc tcaactctac ctaatgatgt acaaactacc      600

tctggtgatc tcaaattgga caaaattgat ccccaaagac aggaacttct agtaaaatta      660

ctagatgtgc ctactggtga ttgtcatatt tctccaaaga atgtcagtga tggggttaaa      720

agggtaagaa cattattaag caatgagaga gattccaaag gcagggatca cctctcagga      780

gtccctactg atgttacagt tactgagact ccagaaaaga acacagaatc cctcatttta      840

agccttaaaa tgagctcatt aggtaaaatc caagtcatgg agaaacaaga gaaaggactt      900

accctgggag tagagacgtg tgggagcaaa ggaaatgcag agaaaagtat gtctgcaaca      960

gaaaagcagg aacggactgt catgagccat ggctgtgaga acttcaacac cagggattca     1020

gtcacaggaa aggagtctca aggggaaaga ccacatttaa gtttgttcat tccgagggag     1080

acgacttacc agtttcattc tgtatcgcag tcaagtagtc aaagtcttgc ctctctagct     1140

acaacatttc ttcaagaaaa gaaagcagaa gcccagaatc ataattgtgt ccctgatgta     1200

aaggcattaa tggagagtcc cgagggacag ttatctctgg agcccaaatc tgatagtcag     1260

ttccaagcat cacacactgg gtgccagagc cctttatgtt cagcccagcg tcacactcct     1320

cagagcccct tcaccaatca tgctgcagct gctggcagga agactcttcg cagctgcatg     1380

gggctggagt ggtttccaga gctctatcct ggttaccttg gactaggggt gttgccaggg     1440

aagcctcagt gttggaatgc aatgacccag aagccacaac ttatcagtcc ccagggggaa     1500

agactctcac aagtttcttt gttggaacga agctcaactc atataaggag tttggaaccc     1560

cctgccggac ttacaacctc caacttctct ctaatgaggc tcttgggagc tgtacaaaaa     1620

ggctggatca ggtgcaacac caccataagg aagagt                               1656


<210>  5955
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  5955
acctccaact gggtgtgcca gacgctggag gatgggcgca ggcgcagcgt ggggctgtgg       60

aggtcctgct ggctggtgga caggacccgg ggagggccga gccctggggc cagagccggc      120

caggtggacg cacatgactg tgaggcgctg ggctggggct ccgaggcagc cggcttccag      180

gagtcccgag gcaccgtcaa actgcagttc gacatgatgc gcgcctgcaa c               231


<210>  5956
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  5956
ggcccgagcc aggccggagc tgaggagaac gactgggttc gcctgcccag caaatgcgaa       60

gtgtgtaaat atgttgctgt ggagctgaag tcagcctttg aggaaaccgg caagaccaag      120

gaggtgattg gcacgggcta tggcatcctg gaccagaagg cctctggagt caaatacacc      180

aagtcggact tgcggttaat cgaagtcact gagaccattt gcaagaggct cctggattat      240

agcctgcaca aggagaggac cggcagcaat cgatttgcca agggcatgtc agagaccttt      300

gagacattac acaacctggt acacaaaggg gtcaaggtgg tgatggacat cccctatgag      360

ctgtggaacg agacttctgc agaggtggct gacctcaaga agcagtgtga tgtgctggtg      420

gaagagtttg aggaggtgat cgaggactgg tacaggaacc accaggagga agacctgact      480

gaattcctct gcgccaacca cgtgctgaag ggaaaagaca ccagttgcct ggcagagcag      540

tggtccggca agaagggaga cacagctgcc ctgggaggga agaagtccaa gaagaagagc      600

agcagggcca aggcagcagg cggcaggagt agcagcagca aacaaaggaa ggagctgggt      660

ggccttgagg gagaccccag ccccgaggag gatgagggca tccagaaggc atcccctctc      720

acacacagcc cccctgatga gctc                                             744


<210>  5957
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  5957
gctccgcaga gactgttgga gagaaggaac tggactcctc aagctatgct ctacctgaaa       60

ggggcacagg gtcgccgctt catctccgac cagagccgga gaaaggacct ctccgaccgg      120

ccactgccgg aaagacgaag cccaaatccc caactactaa ctattccgga ggcagcaacc      180

atcttactgg cgtcccttca gaaatcacca gaagatgaag aaaaaaactt tgatcaaacc      240

agattcctgg aagacagtct gcttaactgg                                       270


<210>  5958
<211>  1317
<212>  DNA
<213>  Homo Sapiens

<400>  5958
cacagcgcca cgcgcttcga ccccacctgg gagtccctgg acgcccgcca gctgcccgcg       60

tggtttgacc aggccaagtt cggcatcttc atccactggg gagtgttttc cgtgcccagc      120

ttcggtagcg agtggttctg gtggtattgg caaaaggaaa agataccgaa gtatgtggaa      180

tttatgaaag ataattaccc tcctagtttc aaatatgaag attttggacc actatttaca      240

gcaaaatttt ttaatgccaa ccagtgggca gatatttttc aggcctctgg tgccaaatac      300

attgtcttaa cttccaaaca tcatgaaggc tttaccttgt gggggtcaga atattcgtgg      360

aactggaatg ccatagatga ggggcccaag agggacattg tcaaggaact tgaggtagcc      420

attaggaaca gaactgacct gcgttttgga ctgtactatt ccctttttga atggtttcat      480

ccgctcttcc ttgaggatga atccagttca ttccataagc ggcaatttcc agtttctaag      540

acattgccag agctctatga gttagtgaac aactatcagc ctgaggttct gtggtcggat      600

ggtgacggag gagcaccgga tcaatactgg aacagcacag gcttcttggc ctggttatat      660

aatgaaagcc cagttcgggg cacagtagtc accaatgatc gttggggagc tggtagcatc      720

tgtaagcatg gtggcttcta tacctgcagt gatcgttata acccaggaca tcttttgcca      780

cataaatggg aaaactgcat gacaatagac aaactgtcct ggggctatag gagggaagct      840

ggaatctctg actatcttac aattgaagaa ttggtgaagc aacttgtaga gacagtttca      900

tgtggaggaa atcttttgat gaatattggg cccacactag atggcaccat ttctgtagtt      960

tttgaggagc gactgaggca agtggggtcc tggctaaaag tcaatggaga agctatttat     1020

gaaacctata cctggcgatc ccagaatgac actgtcaccc cagatgtgtg gtacacatcc     1080

aagcctaaag aaaaattagt ctatgccatt tttcttaaat ggcccacatc aggacagctg     1140

ttccttggcc atcccaaagc tattctgggg gcaacagagg tgaaactact gggccatgga     1200

cagccactta actggatttc tttggagcaa aatggcatta tggtagaact gccacagcta     1260

accattcatc agatgccgtg taaatggggc tgggctctag ccctaactaa tgtgatc        1317


<210>  5959
<211>  1287
<212>  DNA
<213>  Homo Sapiens

<400>  5959
gagcaagtaa aacattcaga gacatattgc atgtttcaag acaagaagta cagagtgggt       60

gagagatggc atccttacct ggaaccttat gggttggttt actgcgtgaa ctgcatctgc      120

tcagagaatg ggaatgtgct ttgcagccga gtcagatgtc caaatgttca ttgcctttct      180

cctgtgcata ttcctcatct gtgctgccct cgctgcccag actccttacc cccagtgaac      240

aataaggtga ccagcaagtc ttgcgagtac aatgggacaa cttaccaaca tggagagctg      300

ttcgtagctg aagggctctt tcagaatcgg caacccaatc aatgcaccca gtgcagctgt      360

tcggagggaa acgtgtattg tggtctcaag acttgcccca aattaacctg tgccttccca      420

gtctctgttc cagattcctg ctgccgggta tgcagaggag atggagaact gtcatgggaa      480

cattctgatg gtgatatctt ccggcaacct gccaacagag aagcaagaca ttcttaccac      540

cgctctcact atgatcctcc accaagccga caggctggag gtctgtcccg ctttcctggg      600

gccagaagtc accggggagc tcttatggat tcccagcaag catcaggaac cattgtgcaa      660

attgtcatca ataacaaaca caagcatgga caagtgtgtg tttccaatgg aaagacctat      720

tctcatggcg agtcctggca cccaaacctc cgggcatttg gcattgtgga gtgtgtgcta      780

tgtacttgta atgtcaccaa gcaagagtgt aagaaaatcc actgccccaa tcgatacccc      840

tgcaagtatc ctcaaaaaat agacggaaaa tgctgcaagg tgtgtccagg taaaaaagca      900

aaagaacttc caggccaaag ctttgacaat aaaggctact tctgcgggga agaaacgatg      960

cctgtgtatg agtctgtatt catggaggat ggggagacaa ccagaaaaat agcactggag     1020

actgagagac cacctcaggt agaggtccac gtttggacta ttcgaaaggg cattctccag     1080

cacttccata ttgagaagat ctccaagagg atgtttgagg agcttcctca cttcaagctg     1140

gtgaccagaa caaccctgag ccagtggaag atcttcaccg aaggagaagc tcagatcagc     1200

cagatgtgtt caagtcgtgt atgcagaaca gagcttgaag atttagtcaa ggttttgtac     1260

ctggagagat ctgaaaaggg ccactgt                                         1287


<210>  5960
<211>  246
<212>  DNA
<213>  Homo Sapiens

<400>  5960
aaaaaggact cacctcccaa aaattccgtg aaggttgatg agctttcact ctactcagtt       60

cctgagggtc aatcgaagta tgtggaggag gcaaggagcc agcttgaaga aagcatctca      120

cagctccgac actattgcga gccatacaca acctggtgtc aggaaacgta ctcccaaact      180

aagcccaaga tgcaaagttt ggttcaatgg gggttagaca gctatgacta tctccaaaat      240

gcacct                                                                 246


<210>  5961
<211>  1671
<212>  DNA
<213>  Homo Sapiens

<400>  5961
gcgccaggtc ccgacggctc cgcgccagat cccgcccact acagggagcg agtcaaggcc       60

atgttctacc acgcctacga cagctacctg gagaatgcct ttcccttcga tgagctgcga      120

cctctcacct gtgacgggca cgacacctgg ggcagttttt ctctgactct aattgatgca      180

ctggacacct tgctgatttt ggggaatgtc tcagaattcc aaagagtggt tgaagtgctc      240

caggacagcg tggactttga tattgatgtg aacgcctctg tgtttgaaac aaacattcga      300

gtggtaggag gactcctgtc tgctcatctg ctctccaaga aggctggggt ggaagtagag      360

gctggatggc cctgttccgg gcctctcctg agaatggctg aggaggcggc ccgaaaactc      420

ctcccagcct ttcagacccc cactggcatg ccatatggaa cagtgaactt acttcatggc      480

gtgaacccag gagagacccc tgtcacctgt acggcaggga ttgggacctt cattgttgaa      540

tttgccaccc tgagcagcct cactggtgac ccggtgttcg aagatgtggc cagagtggct      600

ttgatgcgcc tctgggagag ccggtcagat atcgggctgg tcggcaacca cattgatgtg      660

ctcactggca agtgggtggc ccaggacgca ggcatcgggg ctggcgtgga ctcctacttt      720

gagtacttgg tgaaaggagc catcctgctt caggataaga agctcatggc catgttccta      780

gagtataaca aagccatccg gaactacacc cgcttcgatg actggtacct gtgggttcag      840

atgtacaagg ggactgtgtc catgccagtc ttccagtcct tggaggccta ctggcctggt      900

cttcagagcc tcattggaga cattgacaat gccatgagga ccttcctcaa ctactacact      960

gtatggaagc agtttggggg gctcccggaa ttctacaaca ttcctcaggg atacacagtg     1020

gagaagcgag agggctaccc acttcggcca gaacttattg aaagcgcaat gtacctctac     1080

cgtgccacgg gggatcccac cctcctagaa ctcggaagag atgctgtgga atccattgaa     1140

aaaatcagca aggtggagtg cggatttgca acaatcaaag atctgcgaga ccacaagctg     1200

gacaaccgca tggagtcgtt cttcctggcc gagactgtga aatacctcta cctcctgttt     1260

gacccaacca acttcatcca caacaatggg tccaccttcg acacggtgat caccccctat     1320

ggggagtgca tcctgggggc tggggggtac atcttcaaca cagaagctca ccccatcgac     1380

cctgccgccc tgcactgctg ccagaggctg aaggaagagc agtgggaggt ggaggacttg     1440

atgagggaat tctactctct caaacggagc aggtcgaaat ttcagaaaaa cactgttagt     1500

tcggggccat gggaacctcc agcaaggcca ggaacactct tctcaccaga aaaccatgac     1560

caggcaaggg agaggaagcc tgccaaacag aaggtcccac ttctcagctg ccccagtcag     1620

cccttcacct ccaagttggc attactggga caggttttcc tagactcctc a              1671


<210>  5962
<211>  1122
<212>  DNA
<213>  Homo Sapiens

<400>  5962
accctgtcaa agtcagatgc caaaaaagcc gcctcaaaga cgctgctgga gaagagtcag       60

ttttcagata agccggtgca agaccggggt ttggtggtga cggacctcaa agctgagagt      120

gtggttcttg agcatcgcag ctactgctcg gcaaaggccc gggacagaca ctttgctggg      180

gatgtactgg gctatgtcac tccatggaac agccatggct acgatgtcac caaggtcttt      240

gggagcaagt tcacacagat ctcacccgtc tggctgcagc tgaagagacg tggccgtgag      300

atgtttgagg tcacgggcct ccacgacgtg gaccaagggt ggatgcgagc tgtcaggaag      360

catgccaagg gcctgcacat agtgcctcgg ctcctgtttg aggactggac ttacgatgat      420

ttccggaacg tcttagacag tgaggatgag atagaggagc tgagcaagac cgtggtccag      480

gtggcaaaga accagcattt cgatggcttc gtggtggagg tctggaacca gctgctaagc      540

cagaagcgcg tgggcctcat ccacatgctc acccacttgg ccgaggctct gcaccaggcc      600

cggctgctgg ccctcctggt catcccgcct gccatcaccc ccgggaccga ccagctgggc      660

atgttcacgc acaaggagtt tgagcagctg gcccccgtgc tggatggttt cagcctcatg      720

acctacgact actctacagc gcatcagcct ggccctaatg cacccctgtc ctgggttcga      780

gcctgcgtcc aggtcctgga cccgaagtcc aagtggcgaa gcaaaatcct cctggggctc      840

aacttctatg gtatggacta cgcgacctcc aaggatgccc gtgagcctgt tgtcggggcc      900

aggtacatcc agacactgaa ggaccacagg ccccggatgg tgtgggacag ccaggcctca      960

gagcacttct tcgagtacaa gaagagccgc agtgggaggc acgtcgtctt ctacccaacc     1020

ctgaagtccc tgcaggtgcg gctggagctg gcccgggagc tgggcgttgg ggtctctatc     1080

tgggagctgg gccagggcct ggactacttc tacgacctgc tc                        1122


<210>  5963
<211>  327
<212>  DNA
<213>  Homo Sapiens

<400>  5963
caaaatgcga ccgctgagcc tgagctcaca tccgctggcg ccgcccagcc ggagggcccc       60

gggggtgctg cgagctggga atatggcgac ccccactctc cggtcatcct ctgctcttac      120

ctacctgatg aatttataga atgtgaagac ccagtggatc atgttggaaa tgcaactgca      180

tcccaggaac ttggttatgg ttgtctcaag ttcggcggtc aggcctacag cgacgtggaa      240

cacacttcag tccagtgcca tgccttagat ggaattgagt gtgccagtcc taggaccttt      300

ctacgagaaa ataaaccttg tataaag                                          327


<210>  5964
<211>  243
<212>  DNA
<213>  Homo Sapiens

<400>  5964
acctccgccg ggggcgagga gtcgcttaag tgcgaggacc tcaaagtggg acaatatatt       60

tgtaaagatc caaaaataaa tgacgctacg caagaaccag ttaactgtac aaactacaca      120

gctcatgttt cctgttttcc agcacccaac ataacttgta aggattccag tggcaatgaa      180

acacatttta ctgggaacga agttggtttt ttcaagccca tatcttgccg aaatgtaaat      240

ggc                                                                    243


<210>  5965
<211>  528
<212>  DNA
<213>  Homo Sapiens

<400>  5965
cagagcgaca cgagccctga cacggaggag tcctattcag actggggcct tcggcacctc       60

cggggaagct ttgaatccgt caatagctac ttcgattctt ttctggagct gctgggaggg      120

aagaatggag tctgtcagta caggtgccga tatggaaagg caccaatgcc cagacctggc      180

tacaagcccc aagagcccaa tggctgcggc tcctatttcc tgggtctcaa ggtaccagaa      240

agtatggact tgggcattcc agcaatgaca aagtgctgca accagctgga tgtctgttat      300

gacacttgcg gtgccaacaa atatcgctgt gatgcaaaat tccgatggtg tctccactcg      360

atctgctctg accttaagcg gagtctgggc tttgtctcca aagtggaagc agcctgtgat      420

tccctggttg acactgtgtt caacaccgtg tggaccttgg gctgccgccc ctttatgaat      480

agtcagcggg cagcttgcat ctgtgcagag gaggagaagg aagagtta                   528


<210>  5966
<211>  1182
<212>  DNA
<213>  Homo Sapiens

<400>  5966
tatggcaacg tgcacgtgag cacagagtcc aacctgcagg ccaccgagcg ccgagccgag       60

ggcctataca gtcagctcct agggctcacg gcctcccagt ccaacttgac caaggagctc      120

aacttcacca cccgcgccaa ggatgccatc atgcagatgt ggctgaatgc tcgccgcgac      180

ctggaccgca tcaatgccag cttccgccag tgccagggtg accgggtcat ctacacgaac      240

aatcagaggt acatggctgc catcatcttg agtgagaagc aatgcagaga tcaattcaag      300

gacatgaaca agagctgcga tgccttgctc ttcatgctga atcagaaggt gaagacgctg      360

gaggtggaga tagccaagga gaagaccatt tgcactaagg ataaggaaag cgtgctgctg      420

aacaaacgcg tggcggagga acagctggtt gaatgcgtga aaacccggga gctgcagcac      480

caagagcgcc agctggccaa ggagcaactg caaaaggtgc aagccctctg cctgcccctg      540

gacaaggaca agtttgagat ggaccttcgt aacctgtgga gggactccat tatcccacgc      600

agcctggaca acctgggtta caacctctac catcccctgg gctcggaatt ggcctccatc      660

cgcagagcct gcgaccacat gcccagcctc atgagctcca aggtggagga gctggcccgg      720

agcctccggg cggatatcga acgcgtggcc cgcgagaact cagacctcca acgccagaag      780

ctggaagccc agcagggcct gcgggccagt caggaggcga aacagaaggt ggagaaggag      840

gctcaggccc gggaggccaa gctccaagct gaatgctccc ggcagaccca gctagcgctg      900

gaggagaagg cggtgctgcg gaaggaacga gacaacctgg ccaaggagct ggaagagaag      960

aagagggagg cggagcagct caggatggag ctggccatca gaaactcagc cctggacacc     1020

tgcatcaaga ccaagtcgca gccgatgatg ccagtgtcaa ggcccatggg ccctgtcccc     1080

aacccccagc ccatcgaccc agctagcctg gaggagttca agaggaagat cctggagtcc     1140

cagaggcccc ctgcaggcat ccctgtagcc ccatccagtg gc                        1182


<210>  5967
<211>  696
<212>  DNA
<213>  Homo Sapiens

<400>  5967
acctttgaca gagctgtggc cagcggctgc caacggtgct gtgactctga ggaccccctg       60

gatcctgccc atgtatcctc agcctcttcc tccggccgcc cccacgccct gcctgagatc      120

agaccctaca ttaatatcac catcctgaag ggtgacaaag gggacccagg cccaatgggc      180

ctgccagggt acatgggcag ggagggtccc caaggggagc ctggccctca gggcagcaag      240

ggtgacaagg gggagatggg cagccccggc gccccgtgcc agaagcgctt cttcgccttc      300

tcagtgggcc gcaagacggc cctgcacagc ggcgaggact tccagacact gctcttcgaa      360

agggtctttg tgaaccttga tgggtgcttt gacatggcga ccggccagtt tgctgctccc      420

ctgcgtggca tctacttctt cagcctcaat gtgcacagct ggaattacaa ggagacgtac      480

gtgcacatta tgcataacca gaaagaggct gtcatcctgt acgcgcagcc cagcgagcgc      540

agcatcatgc agagccagag tgtgatgctg gacctggcct acggggaccg cgtctgggtg      600

cggctcttca agcgccagcg cgagaacgcc atctacagca acgacttcga cacctacatc      660

accttcagcg gccacctcat caaggccgag gacgac                                696


<210>  5968
<211>  768
<212>  DNA
<213>  Homo Sapiens

<400>  5968
cgtgtgcccc atgtccaggg ggaacagcag gagtgggagg ggactgagga gctgccgtcg       60

cctccggacc atgccgagag ggctgaagaa caacatgaaa aatacaggcc cagtcaggac      120

caggggctcc ctgcttcccg gtgcttgcgc tgctgtgacc ccggtacctc catgtacccg      180

gcgaccgccg tgccccagat caacatcact atcttgaaag gggagaaggg tgaccgcgga      240

gatcgaggcc tccaagggaa atatggcaaa acaggctcag caggggccag gggccacact      300

ggacccaaag ggcagaaggg ctccatgggg gcccctgggg agcggtgcaa gagccactac      360

gccgcctttt cggtgggccg gaagaagccc atgcacagca accactacta ccagacggtg      420

atcttcgaca cggagttcgt gaacctctac gaccacttca acatgttcac cggcaagttc      480

tactgctacg tgcccggcct ctacttcttc agcctcaacg tgcacacctg gaaccagaag      540

gagacctacc tgcacatcat gaagaacgag gaggaggtgg tgatcttgtt cgcgcaggtg      600

ggcgaccgca gcatcatgca aagccagagc ctgatgctgg agctgcgaga gcaggaccag      660

gtgtgggtac gcctctacaa gggcgaacgt gagaacgcca tcttcagcga ggagctggac      720

acctacatca ccttcagtgg ctacctggtc aagcacgcca ccgagccc                   768


<210>  5969
<211>  819
<212>  DNA
<213>  Homo Sapiens

<400>  5969
caaccccggg gtaatcagtt gaaaggagag aactactccc ccaggtatat ctgcagcatt       60

cctggcttgc ctggacctcc agggccccct ggagcaaatg gttcccctgg gccccatggt      120

cgcatcggcc ttccaggaag agatggtaga gacggcagga aaggagagaa aggtgaaaag      180

ggaactgcag gtttgagagg taagactgga ccgctaggtc ttgccggtga gaaaggggac      240

caaggagaga ctgggaagaa aggacccata ggaccagagg gagagaaagg agaagtaggt      300

ccaattggtc ctcctggacc aaagggagac agaggagaac aaggggaccc ggggctgcct      360

ggagtttgca gatgtggaag catcgtgctc aaatccgcct tttctgttgg catcacaacc      420

agctacccag aagaaagact acctattata tttaacaagg tcctcttcaa cgagggagag      480

cactacaacc ctgccacagg gaagttcatc tgtgctttcc cagggatcta ttacttttct      540

tatgatatca cattggctaa taagcatctg gcaatcggac tggtacacaa tgggcaatac      600

cggataaaga ccttcgacgc caacacagga aaccatgatg tggcttcggg gtccacagtc      660

atctatctgc agccagaaga tgaagtctgg ctggagattt tcttcacaga ccagaatggc      720

ctcttctcag acccaggttg ggcagacagc ttattctccg ggtttctctt atacgttgac      780

acagattacc tagattccat atcagaagat gatgaattg                             819


<210>  5970
<211>  891
<212>  DNA
<213>  Homo Sapiens

<400>  5970
caagatgaat acatggaggt gagcggaaga actaataaag tggtggcaag aatagtgcaa       60

agccaccagc agactggccg tagcggctcc aggagggaga aagtgagaga gcggagccat      120

cctaaaactg ggactgtgga taataacact tctacagacc taaaatccct gagaccagat      180

gagctaccgc accccgaggt agatgaccta gcccagatca ccacattctg gggccagtct      240

ccacaaaccg gaggactacc cccagactgc agtaagtgtt gtcatggaga ctacagcttt      300

cgaggctacc aaggcccccc tgggccaccg ggccctcctg gcattccagg aaaccatgga      360

aacaatggca acaatggagc cactggtcat gaaggagcca aaggtgagaa gggcgacaaa      420

ggtgacctgg ggcctcgagg ggagcggggg cagcatggcc ccaaaggaga gaagggctac      480

ccggggattc caccagaact tcagattgca ttcatggctt ctctggcaac ccacttcagc      540

aatcagaaca gtgggattat cttcagcagt gttgagacca acattggaaa cttctttgat      600

gtcatgactg gtagatttgg ggccccagta tcaggtgtgt atttcttcac cttcagcatg      660

atgaagcatg aggatgttga ggaagtgtat gtgtacctta tgcacaatgg caacacagtc      720

ttcagcatgt acagctatga aatgaagggc aaatcagata catccagcaa tcatgctgtg      780

ctgaagctag ccaaagggga tgaggtttgg ctgcgaatgg gcaatggcgc tctccatggg      840

gaccaccaac gcttctccac ctttgcagga ttcctgctct ttgaaactaa g               891


<210>  5971
<211>  1653
<212>  DNA
<213>  Homo Sapiens

<400>  5971
gaaggaacac tttgtgattt tccaaaaata caccatggat ttctgtatga tgaagaagat       60

tataaccctt tttcccaagt tcctacaggg gaagttttct attactcctg tgaatataat      120

tttgtgtctc cttcaaaatc cttttggact cgcataacat gcacagaaga aggatggtca      180

ccaacaccga agtgtctcag aatgtgttcc tttccttttg tgaaaaatgg tcattctgaa      240

tcttcaggac taatacatct ggaaggtgat actgtacaaa ttatttgcaa cacaggatac      300

agccttcaaa acaatgagaa aaacatttcg tgtgtagaac ggggctggtc cactcctccc      360

atatgcagct tcactaaagg agaatgtcat gttccaattt tagaagccaa tgtagatgct      420

cagccaaaaa aagaaagcta caaagttgga gacgtgttga aattctcctg cagaaaaaat      480

cttataagag ttggatcaga ctcagttcaa tgttaccaat ttgggtggtc acctaacttt      540

ccaacatgca aaggacaagt acgatcatgt ggtccacctc ctcaactctc caatggtgaa      600

gttaaggaga taagaaaaga ggaatatgga cacaatgaag tagtggaata tgattgcaat      660

cctaatttta taataaacgg gcctaagaaa atacaatgtg tggatggaga atggacaact      720

ttacccactt gtgttgaaca agtgaaaaca tgtggataca tacctgaact cgagtacggt      780

tatgttcagc cgtctgtccc tccctatcaa catggagttt cagtcgaggt gaattgcaga      840

aatgaatatg caatgattgg aaataacatg attacctgta ttaatggaat atggacagag      900

cttcctatgt gtgttgcaac acaccaactt aagaggtgca aaatagcagg agttaatata      960

aaaacattac tcaagctatc tgggaaagaa tttaatcata attctagaat acgttacaga     1020

tgttcagaca tcttcagata caggcactca gtctgtataa acgggaaatg gaatcctgaa     1080

gtagactgca cagaaaaaag ggaacaattc tgcccaccgc cacctcagat acctaatgct     1140

cagaatatga caaccacagt gaattatcag gatggagaaa aagtagctgt tctctgtaaa     1200

gaaaactatc tacttccaga agcaaaagaa attgtatgta aagatggacg atggcaatca     1260

ttaccacgct gtgttgagtc tactgcatat tgtgggcccc ctccatctat taacaatgga     1320

gataccacct cattcccatt atcagtatat cctccagggt caacagtgac gtaccgttgc     1380

cagtccttct ataaactcca gggctctgta actgtaacat gcagaaataa acagtggtca     1440

gaaccaccaa gatgcctaga tccatgtgtg gtatctgaag aaaacatgaa caaaaataac     1500

atacagttaa aatggagaaa cgatggaaaa ctctatgcaa aaacagggga tgctgttgaa     1560

ttccagtgta aattcccaca taaagcgatg atatcatcac caccatttcg agcaatctgt     1620

caggaaggga aatttgaata tcctatatgt gaa                                  1653


<210>  5972
<211>  612
<212>  DNA
<213>  Homo Sapiens

<400>  5972
gaagcatttg actcggtctt gggtgatacg gcgtcttgcc accgggcctg tcagttgacc       60

taccccttgc acacctaccc taaggaagag gagttgtacg catgtcagag aggttgcagg      120

ctgttttcaa tttgtcagtt tgtggatgat ggaattgact taaatcgaac taaattggaa      180

tgtgaatctg catgtacaga agcatattcc caatctgatg agcaatatgc ttgccatctt      240

ggttgccaga atcagctgcc attcgctgaa ctgagacaag aacaacttat gtccctgatg      300

ccaaaaatgc acctactctt tcctctaact ctggtgaggt cattctggag tgacatgatg      360

gactccgcac agagcttcat aacctcttca tggacttttt atcttcaagc cgatgacgga      420

aaaatagtta tattccagtc taagccagaa atccagtacg caccacattt ggagcaggag      480

cctacaaatt tgagagaatc atctctaagc aaaatgtcct cagatctgca aatgagaaat      540

tcacaagcgc acaggaattt tcttgaagat ggagaaagtg atggcttttt aagatgcctc      600

tctcttaact ct                                                          612


<210>  5973
<211>  753
<212>  DNA
<213>  Homo Sapiens

<400>  5973
caaaacgcct cccggggaag gcgccagcga agaatgcatc ctaacgttag tcaaggctgc       60

caaggaggct gtgcaacatg ctcagattac aatggatgtt tgtcatgtaa gcccagacta      120

ttttttgctc tggaaagaat tggcatgaag cagattggag tatgtctctc ttcatgtcca      180

agtggatatt atggaactcg atatccagat ataaataagt gtacaaaatg caaagctgac      240

tgtgatacct gtttcaacaa aaatttctgc acaaaatgta aaagtggatt ttacttacac      300

cttggaaagt gccttgacaa ttgcccagaa gggttggaag ccaacaacca tactatggag      360

tgtgtcagta ttgtgcactg tgaggtcagt gaatggaatc cttggagtcc atgcacgaag      420

aagggaaaaa catgtggctt caaaagaggg actgaaacac gggtccgaga aataatacag      480

catccttcag caaagggtaa cctgtgtccc ccaacaaatg agacaagaaa gtgtacagtg      540

caaaggaaga agtgtcagaa gggagaacga ggaaaaaaag gaagggagag gaaaagaaaa      600

aaacctaata aaggagaaag taaagaagca atacctgaca gcaaaagtct ggaatccagc      660

aaagaaatcc cagagcaacg agaaaacaaa cagcagcaga agaagcgaaa agtccaagat      720

aaacagaaat cggtatcagt cagcactgta cac                                   753


<210>  5974
<211>  1143
<212>  DNA
<213>  Homo Sapiens

<400>  5974
cagttctggc agggccacac agggatcagg tacaaggagc agagggagag ctgtcccaag       60

cacgctgttc gctgtgacgg ggtggtggac tgcaagctga agagtgacga gctgggctgc      120

gtgaggtttg actgggacaa gtctctgctt aaaatctact ctgggtcctc ccatcagtgg      180

cttcccatct gtagcagcaa ctggaatgac tcctactcag agaagacctg ccagcagctg      240

ggtttcgaga gtgctcaccg gacaaccgag gttgcccaca gggattttgc caacagcttc      300

tcaatcttga gatacaactc caccatccag gaaagcctcc acaggtctga atgcccttcc      360

cagcggtata tctccctcca gtgttcccac tgcggactga gggccatgac cgggcggatc      420

gtgggagggg cgctggcctc ggatagcaag tggccttggc aagtgagtct gcacttcggc      480

accacccaca tctgtggagg cacgctcatt gacgcccagt gggtgctcac tgccgcccac      540

tgcttcttcg tgacccggga gaaggtcctg gagggctgga aggtgtacgc gggcaccagc      600

aacctgcacc agttgcctga ggcagcctcc attgccgaga tcatcatcaa cagcaattac      660

accgatgagg aggacgacta tgacatcgcc ctcatgcggc tgtccaagcc cctgaccctg      720

tccgctcaca tccaccctgc ttgcctcccc atgcatggac agacctttag cctcaatgag      780

acctgctgga tcacaggctt tggcaagacc agggagacag atgacaagac atcccccttc      840

ctccgggagg tgcaggtcaa tctcatcgac ttcaagaaat gcaatgacta cttggtctat      900

gacagttacc ttaccccaag gatgatgtgt gctggggacc ttcgtggggg cagagactcc      960

tgccagggag acagcggggg gcctcttgtc tgtgagcaga acaaccgctg gtacctggca     1020

ggtgtcacca gctggggcac aggctgtggc cagagaaaca aacctggtgt gtacaccaaa     1080

gtgacagaag ttcttccctg gatttacagc aagatggaga gcgaggtgcg attcagaaaa     1140

tcc                                                                   1143


<210>  5975
<211>  3402
<212>  DNA
<213>  Homo Sapiens

<400>  5975
aacgtggccc cgaagttcct agccaacatg acgtcagtga tcctgcctga ggacctgcct       60

gtgggtgccc aggccttctg gttggtagcg gaagaccagg acaatgaccc tctgacctat      120

gggatgagcg gccccaatgc ctacttcttc gctgtcactc cgaaaactgg ggaagtgaag      180

ctggccagcg ctctggacta cgagacactc tacacattca aagtcaccat ctccgtgagc      240

gacccctaca tccaggtgca gagggagatg ctggtgattg tggaagatag aaacgacaac      300

gcacccgttt tccagaacac cgctttctcc accagcatca acgagaccct gcccgtgggc      360

agtgtggtgt tctccgtgct ggccgtggat aaagacatgg ggtctgcagg catggtcgtg      420

tactccatag agaaggtcat ccctagcact ggggacagcg agcatctctt ccggatcctg      480

gccaatggct ccatcgtcct caatggcagc ctcagctaca acaacaagag cgctttctac      540

cagctggagc tgaaggcctg tgacttgggc ggcatgtacc acaacacctt caccatccag      600

tgctccctgc ctgtcttcct gtccatctcc gtggtggacc agcctgacct tgacccccag      660

tttgtcaggg agttttactc ggcctctgtg gctgaggatg cagccaaggg aacctcggtg      720

ctgacggtgg aggctgtgga tggcgacaaa ggcatcaatg accctgtgat ctacagcatc      780

tcctactcca cgcggcccgg ctggtttgac atcggggcag atggggtgat cagggtcaac      840

ggctccctgg accgtgagca gctgctggag gcggatgagg aggtgcagct gcaggtcacg      900

gccaccgaga cacacctcaa catctacggg caggaggcca aggtgagcat ctgggtgaca      960

gtgagagtga tggacgtcaa tgaccacaaa cctgagtttt acaactgcag cctcccagcc     1020

tgcaccttca cccccgaaga ggcccaagtg aacttcactg gctacgtgga cgagcatgcc     1080

tccccccgca tccccatcga tgacctcacc atggtggtct acgacccgga caagggcagc     1140

aatggcacct tcctgttgtc gctggggggc cccgatgcag aagccttcag cgtctccccg     1200

gagcgggcag cgggctcagc ctccgttcag gtgctggtga gagtatccgc gctggtggac     1260

tacgagaggc agacggcgat ggcggtgcag gttgtggcca cagactccgt cagccagaac     1320

ttctccgtcg ccatggtgac catccacctt agagacatta atgaccacag gcccacgttt     1380

ccccagagct tgtacgtcct cacggtgcca gagcacagcg ccaccggctc tgtggtcacc     1440

gacagcatcc acgccacgga cccagacacg ggcgcgtggg gccaaattac ctacagcctg     1500

ctcccaggaa atggggcaga cctcttccaa gtggatcccg tctcagggac ggtgacggtg     1560

aggaacggtg agctgctgga ccgggagagc caggccgtgt actacctgac gctgcaggcc     1620

acagatggcg ggaacctgtc ctcctccacc acactgcaga tccacctgct ggacatcaac     1680

gacaatgcac ccgtggttag cggctcctac aacatcttcg tccaggagga ggagggcaat     1740

gtctccgtga ccatccaggc ccacgacaat gatgagccgg gcaccaacaa cagccgtctg     1800

ctcttcaacc tgctgcctgg cccctacagc cacaacttct ccttggaccc tgacacaggg     1860

ctcctcagaa acctggggcc cctggacaga gaggccatcg accccgccct ggagggccgc     1920

attgtgctga cagtgcttgt gtctgactgc ggcgagcctg tcctcggcac caaagtcaat     1980

gtcaccatca ctgtggagga catcaatgat aacctgccca tcttcaatca gtccagctac     2040

aactttacgg tgaaggagga ggatccagga gtgctagtgg gcgtggtgaa ggcctgggac     2100

gcggaccaga cggaagccaa caaccgcatc agcttcagcc tgtcggggag tggtgccaac     2160

tacttcatga tccgaggctt ggtgctgggg gctgggtggg ctgagggcta cctccggctg     2220

cccccggacg tgagcctgga ttacgagaca cagcccgtct tcaacttgac agtgagtgct     2280

gagaacccag acccccaggg gggtgagacc atagtagacg tctgcgtgaa tgtgaaagac     2340

gtgaacgaca atccccccac cctggatgta gcctcactcc ggggcatccg tgtggctgag     2400

aatggctcac agcacggcca ggtggctgtg gtggttgcct cggatgtgga caccagtgcc     2460

cagctggaga tacagcttgt gaacattctc tgcaccaagg ccggggtcga tgtgggcagc     2520

ctatgctggg gctggttctc agtggcggcc aacggctctg tgtacatcaa ccagagcaaa     2580

gccatcgact acgaggcctg tgacctggtc acgctggttg tgcgggcctg tgacctagcc     2640

acggaccccg gcttccaggc ctacagcaac aatggaagcc tcctcattac cattgaggac     2700

gtgaatgaca atgcacccta ttttctgcct gagaataaga cttttgtgat catccctgaa     2760

ctcgtgctgc ccaaccggga ggtggcttct gtccgggcca gagacgatga ttcagggaac     2820

aatggcgtca tcctgttctc catcctccga gtagacttca tctctaagga cggggccacc     2880

atccctttcc agggtgtctt ctcgatcttc acctcctccg aggccgacgt gttcgctggg     2940

agcattcagc cggtgaccag cctcgactcc actctccaag gcacctacca agtgacagtc     3000

caggccaggg acagaccttc cttgggtcct ttcctggaag ccaccaccac cctgaatctc     3060

ttcaccgtgg accagagtta ccgctcgcgg ctgcagttct ccacaccgaa ggaggaggtg     3120

ggcgccaaca gacaggcgat taatgcggct cttacccagg caaccaggac tacagtatac     3180

attgtggaca ttcaggacat agattctgca gctcgggccc gacctcactc ctacctcgat     3240

gcctactttg tcttccccaa tgggtcagcc ctgacccttg atgagctgag tgtgatgatc     3300

cggaatgatc aggactcgct gatgcagctg ctgcagctgg ggctggtggt gctgggctcc     3360

caggagagcc aggagtcaga cctgtcgaaa cagctcatca gt                        3402


<210>  5976
<211>  192
<212>  DNA
<213>  Homo Sapiens

<400>  5976
cttctgtata atagatttga tctggagctc ttcactcccg gcaacctaga aagagagtgc       60

aatgaagaac tttgcaatta tgaggaagcc agagagattt ttgtggatga agataaaacg      120

attgcatttt ggcaggaata ttcagctaaa ggaccaacca caaaatcaga tggcaacaga      180

gagaaaatag at                                                          192


<210>  5977
<211>  177
<212>  DNA
<213>  Homo Sapiens

<400>  5977
gccaatgagt tcctggagga gctgcgccag ggcaccatcg agcgagagtg catggaggag       60

atctgcagct acgaggaggt caaggaagtg tttgagaaca aagagaaaac gatggagttc      120

tggaaagggt acccaaatgc agtctactct gtccgagacc cctcgcagag ctcagat         177


<210>  5978
<211>  1101
<212>  DNA
<213>  Homo Sapiens

<400>  5978
ctgccagaag gacccctggt gttcgtggct ctggtattcc gccatggcga ccgggccccg       60

ctggcctcct accccatgga cccacacaag gaggtggcct ccaccctgtg gccacgaggc      120

ctgggccagc tgaccacgga gggggtccgc cagcagctgg agctgggccg cttcctgagg      180

agccgctacg aggccttcct gagtccggag taccggcggg aggaggtgta catccgcagc      240

acggactttg accgcacgct ggagagtgcc caggccaacc ttgccgggct gtttcccgag      300

gctgctccag ggagccccga ggcccgctgg aggccgatcc cggtgcacac ggtgcccgtg      360

gctgaggata agctgctgag gttccccatg cgcagctgtc cccgatacca cgagctgctg      420

cgggaggcca ccgaggccgc cgagtaccag gaggccctgg agggctggac gggcttcctg      480

agtcgcctgg agaacttcac gggactgtcg ctggttggag agccactgcg cagggcatgg      540

aaggttctgg acaccctcat gtgccagcaa gcccacggtc ttccactacc agcctgggcc      600

tccccagatg tcctgcggac tcttgcccag atctcggctt tggatattgg agcccacgtg      660

ggcccacccc gggcagcaga gaaggcccag ctgacagggg ggatcctgct gaatgctatc      720

cttgcaaact tctcccgggt ccagcgcctg gggctgcccc tcaagatggt catgtactca      780

gctcatgaca gcaccctgct ggccctccag ggggccctgg gcctctatga tggacacacc      840

ccgccatatg ctgcctgcct cggctttgag ttccggaagc acctggggaa tcccgccaaa      900

gatggaggga atgtcaccgt ctccctcttc taccgcaatg actccgccca cctgcccctg      960

cctctcagcc tccccgggtg cccggccccc tgtccactag gccgcttcta ccagctgact     1020

gccccggccc ggcctcccgc ccatggggtc tcctgccatg gcccctatga ggctgccatc     1080

cccccagctc cagtggtgcc c                                               1101


<210>  5979
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  5979
caggagcagg cccagaccac cgactggaga gccaccctga agaccatccg gaacggcgtt       60

cataagatag acacgtacct gaacgccgcc ttggacctcc tgggaggcga ggacggtctc      120

tgccagtata aatgcagtga cggatctaag cctttcccac gttatggtta taaaccctcc      180

ccaccgaatg gatgtggctc tccactgttt ggtgttcatc ttaacattgg tatcccttcc      240

ctgacaaagt gttgcaacca acacgacagg tgctatgaga cctgtggcaa aagcaagaat      300

gactgtgatg aagaattcca gtattgcctc tccaagatct gccgagatgt acagaaaaca      360

ctaggactaa ctcagcatgt tcaggcatgt gaaacaacag tggagctctt gtttgacagt      420

gttatacatt taggttgtaa accatatctg gacagccaac gagccgcatg caggtgtcat      480

tatgaagaaa aaactgatct t                                                501


<210>  5980
<211>  444
<212>  DNA
<213>  Homo Sapiens

<400>  5980
agcctgctca acctgaaggc catggtggag gccgtcacag ggaggagcgc catcctgtcc       60

ttcgtgggct acggttgcta ctgtgggctg gggggccgtg gccagcccaa ggatgaggtg      120

gactggtgct gccacgccca cgactgctgc taccaggaac tctttgacca aggctgtcac      180

ccctatgtgg accactatga tcacaccatc gagaacaaca ctgagatagt ctgcagtgac      240

ctcaacaaga cagagtgtga caagcagaca tgcatgtgtg acaagaacat ggttctgtgc      300

ctcatgaacc agacgtaccg agaggagtac cgtggcttcc tcaatgtcta ctgccagggc      360

cccacgccca actgcagcat ctatgaaccg ccccctgagg aggtcacctg cagtcaccaa      420

tccccagcgc cccccgcccc tccc                                             444


<210>  5981
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5981
aggcgagacg accctcactc tctttgctat gacatcaccg tcatccctaa gttcagacct       60

ggaccacggt ggtgtgcggt tcaaggccag gtggatgaaa agacttttct tcactatgac      120

tgtggcaaca agacagtcac acccgtcagt cccctgggga agaaactaaa tgtcacaatg      180

gcctggaaag cacagaaccc agtactgaga gaggtggtgg acatacttac agagcaactg      240

cttgacattc agctggagaa ttacacaccc aaggaacccc tcaccctgca ggcaaggatg      300

tcttgtgagc agaaagctga aggacacagc agtggatctt ggcagttcag tatcgatgga      360

cagaccttcc tactctttga ctcagagaag agaatgtgga caacggttca tcctggagcc      420

agaaagatga aagaaaagtg ggagaatgac aaggatgtgg ccatgtcctt ccattacatc      480

tcaatgggag actgcatagg atggcttgag gacttcttga tgggcatgga cagcaccctg      540

gagccaagtg caggagcacc actcgccatg tcc                                   573


<210>  5982
<211>  573
<212>  DNA
<213>  Homo Sapiens

<400>  5982
ggatgggtcg acacacactg tctttgctat gacttcatca tcactcctaa gtccagacct       60

gaaccacagt ggtgtgaagt tcaaggcctg gtggatgaaa ggccttttct tcactatgac      120

tgtgttaacc acaaggccaa agcctttgct tctctgggga agaaagtcaa tgtcacaaaa      180

acctgggaag aacaaactga aacactaaga gacgtggtgg atttccttaa agggcaactg      240

cttgacattc aagtggagaa tttaataccc attgagcccc tcaccctgca ggccaggatg      300

tcttgtgagc atgaagccca tggacacggc agaggatctt ggcagttcct cttcaatgga      360

cagaagttcc tcctctttga ctcaaacaac agaaagtgga cagcacttca tcctggagcc      420

aagaagatga cagagaagtg ggagaagaac agggatgtga ccatgttctt ccagaagatt      480

tcactggggg attgtaagat gtggcttgaa gaatttttga tgtactggga acaaatgctg      540

gatccaacaa aaccaccctc tctggcccca ggc                                   573


<210>  5983
<211>  2250
<212>  DNA
<213>  Homo Sapiens

<400>  5983
gtctcagcca cggcggctgc tgtggtcccc gagcagcatg cctccgtagc tggccagcat       60

cccctggact ggctgctcac agaccggggc cccttccacc gcgctcagga gtatgctgac      120

ttcatggagc ggtaccgcca gggtttcacc accaggtaca ggatttatag ggagtttgcc      180

cgttggaagg tgaacaactt ggctctggaa aggaaggact tcttcagttt gccattgcct      240

cttgccccag agtttatccg gaacattcgc ctccttggaa ggagacccaa tctgcaacag      300

gttacagaaa atctgattaa aaagtacggc actcatttct tactttctgc cacccttgga      360

ggagaagagt ccctgaccat ttttgtggac aagcagaaac tgggaagaaa gacagagaca      420

acaggaggtg cctctataat cgggggcagt gggaacagca cagctgtgtc cctggagacc      480

ctgcaccagc tggccgcctc ctacttcatc gacagagaga gcacgctgcg acggctgcac      540

catatccaga tagccacggg ggccatcaag gtcaccgaga ccaggaccgg tcctctgggc      600

tgcagcaact atgacaatct ggactcagtc agttctgtct tggtacagag tccagagaac      660

aaagtacagt tacttggcct tcaggtgctg ctgcctgagt atctgcgtga gcgctttgta      720

gctgcagcac tcagctacat cacatgcagc tctgagggtg agctcgtctg caaggagaat      780

gactgctggt gcaagtgcag ccccaccttc cctgaatgca actgccctga tgctgacatc      840

caggccatgg aggacagcct gctgcagatc caggactcct gggccactca caaccggcag      900

tttgaagagt cagaagagtt ccaggccctg ctgaaaaggc tgcccgatga ccggttcctg      960

aactccacag ctatctccca gttctgggcc atggacacca gccttcagca ccgctaccag     1020

cagctgggag ctggcttgaa agtgctgttc aaaaagaccc atcggatcct acgccggctc     1080

ttcaacctct gcaagcgctg ccatcgccag cctcgcttcc gcctgcccaa ggagaggtcc     1140

ttgtcctact ggtggaaccg aatccagtcc ctcctctact gtggggaaag cacctttcct     1200

ggcactttcc tggaacagag ccacagctgc acctgcccct atgaccaatc ttcctgccag     1260

ggccccatcc catgtgcctt gggcgaaggg cccgcgtgtg cccactgtgc tccagacaat     1320

agcacacgct gtgggagctg caacccgggc tatgtgctgg cccaggggct gtgccggcca     1380

gaggtggccg agtccctgga aaactttctt gggctggaga cagacttgca ggacctggag     1440

ctaaagtacc tgctgcagaa gcaggatagc cgcattgagg tacactccat cttcatcagc     1500

aatgacatgc ggctgggcag ctggtttgac ccttcctgga ggaagcgcat gctgctcacc     1560

ctgaagagca acaagtacaa gcctgggctg gtgcacgtga tgttggcctt gtccttgcag     1620

atctgtctca ccaagaacag caccctggag cctgtcatgg ccatctacgt caaccccttt     1680

gggggcagcc actctgagag ctggttcatg cctgtgaatg agggcagctt tcctgactgg     1740

gaaaggacta acgtggatgc agctgcccag tgccaaaact ggactatcac cttggggaat     1800

aggtggaaga ctttctttga gacagttcat gtttacctac ggagccgaat caagtccctg     1860

gatgacagct ccaatgagac aatctactat gagcccctgg agatgactga tccctctaag     1920

aatttgggtt acatgaaaat taacaccttg caggtctttg gctacagcct gccctttgac     1980

ccagatgcta tccgggactt aattctccag ttggactacc catatactca aggttcccag     2040

gactctgcac tcttgcagct cattgagctc agggaccggg tgaaccagct ttctccacct     2100

ggcaaagtcc gacttgacct tttctcctgc ttgctccggc atcggcttaa gctggccaac     2160

aatgaggtgg gcaggatcca gtcctccctg agggctttca attctaagct gccaaaccct     2220

gtggaatatg agaccggcaa actctgtagc                                      2250


<210>  5984
<211>  387
<212>  DNA
<213>  Homo Sapiens

<400>  5984
ggcttggagc tggctgtgtc cgtgggctcc agcgacttct gtgtggaccc tgacgcctac       60

gtgaccaaaa tggtggagga gtactcggtg ctgagtgggg acatcctgca gtactacctg      120

gcctgctcgc cccgcgccgc caaccccttc cagcagaagc tgtcgggcag ccacaaggca      180

ctggtggaga tgcaggatgt cgtggctgag cttctgagga ccgtcccctg ggagcagccg      240

gccactaagg accccctcct ccgcgtccag gaggtgctga atggcacgga ggtgaacctg      300

cagcacctca ccgccctggt ggactgccgc agcctgcatc tggactacgt gcaagcgctg      360

accggcttct gctatgacgg cgtggag                                          387


<210>  5985
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  5985
gaaagaatgc taaagatgtt attaaagaca tatggtcaga atggtcatac ccactttgga       60

aatgataact ttggtcctca agaaaaaact catcaaccta aagcattacc tgccatcaat      120

ggtgtgacat gctatgcaaa tcctgctgtc acagaagcta atggacatat ccattttgat      180

aatgtcagtg tggtatctct acaggatgga aaaaaagagc caagttcatg tacctgtttg      240

aaggggccca aactgtcaga aatagggacg                                       270


<210>  5986
<211>  1338
<212>  DNA
<213>  Homo Sapiens

<400>  5986
gcccagcagg gtcgtgggcg ccgggagcta gcaccgggtc tgcacctgcg gggcatccgg       60

gacgcgggag gccggtactg ccaggagcag gacctgtgct gccgcggccg tgccgacgac      120

tgtgccctgc cctacctggg cgccatctgt tactgtgacc tcttctgcaa ccgcacggtc      180

tccgactgct gccctgactt ctgggacttc tgcctcggcg tgccaccccc ttttcccccg      240

atccaaggat gtatgcatgg aggtcgtatc tatccagtct tgggaacgta ctgggacaac      300

tgtaaccgtt gcacctgcca ggagaacagg cagtggcagt gtgaccaaga accatgcctg      360

gtggatccag acatgatcaa agccatcaac cagggcaact atggctggca ggctgggaac      420

cacagcgcct tctggggcat gaccctggat gagggcattc gctaccgcct gggcaccatc      480

cgcccatctt cctcggtcat gaacatgcat gaaatttata cagtgctgaa cccaggggag      540

gtgcttccca cagccttcga ggcctctgag aagtggccca acctgattca tgagcctctt      600

gaccaaggca actgtgcagg ctcctgggcc ttctccacag cagctgtggc atccgatcgt      660

gtctcaatcc attctctggg acacatgacg cctgtcctgt cgccccagaa cctgctgtct      720

tgtgacaccc accagcagca gggctgccgc ggtgggcgtc tcgatggtgc ctggtggttc      780

ctgcgtcgcc gaggggtggt gtctgaccac tgctacccct tctcgggccg tgaacgagac      840

gaggctggcc ctgcgccccc ctgtatgatg cacagccgag ccatgggtcg gggcaagcgc      900

caggccactg cccactgccc caacagctat gttaataaca atgacatcta ccaggtcact      960

cctgtctacc gcctcggctc caacgacaag gagatcatga aggagctgat ggagaatggc     1020

cctgtccaag ccctcatgga ggtgcatgag gacttcttcc tatacaaggg aggcatctac     1080

agccacacgc cagtgagcct tgggaggcca gagagatacc gccggcatgg gacccactca     1140

gtcaagatca caggatgggg agaggagacg ctgccagatg gaaggacgct caaatactgg     1200

actgcggcca actcctgggg cccagcctgg ggcgagaggg gccacttccg catcgtgcgc     1260

ggcgtcaatg agtgcgacat cgagagcttc gtgctgggcg tctggggccg cgtgggcatg     1320

gaggacatgg gtcatcac                                                   1338


<210>  5987
<211>  855
<212>  DNA
<213>  Homo Sapiens

<400>  5987
gccaggatac ctgttccccc agcctgtggg aagccccagc agctgaaccg ggttgtgggc       60

ggcgaggaca gcactgacag cgagtggccc tggatcgtga gcatccagaa gaatgggacc      120

caccactgcg caggttctct gctcaccagc cgctgggtga tcactgctgc ccactgtttc      180

aaggacaacc tgaacaaacc atacctgttc tctgtgctgc tgggggcctg gcagctgggg      240

aaccctggct ctcggtccca gaaggtgggt gttgcctggg tggagcccca ccctgtgtat      300

tcctggaagg aaggtgcctg tgcagacatt gccctggtgc gtctcgagcg ctccatacag      360

ttctcagagc gggtcctgcc catctgccta cctgatgcct ctatccacct ccctccaaac      420

acccactgct ggatctcagg ctgggggagc atccaagatg gagttccctt gccccaccct      480

cagaccctgc agaagctgaa ggttcctatc atcgactcgg aagtctgcag ccatctgtac      540

tggcggggag caggacaggg acccatcact gaggacatgc tgtgtgccgg ctacttggag      600

ggggagcggg atgcttgtct gggcgactcc gggggccccc tcatgtgcca ggtggacggc      660

gcctggctgc tggccggcat catcagctgg ggcgagggct gtgccgagcg caacaggccc      720

ggggtctaca tcagcctctc tgcgcaccgc tcctgggtgg agaagatcgt gcaaggggtg      780

cagctccgcg ggcgcgctca ggggggtggg gccctcaggg caccgagcca gggctctggg      840

gccgccgcgc gctcc                                                       855


<210>  5988
<211>  1146
<212>  DNA
<213>  Homo Sapiens

<400>  5988
atgcccaggt cagcacccaa tgacattctg gacctccgcc tccccccgga gcccgtgctc       60

aatgccaaca cagtgtgcct aacattgcca ggcctgagcc ggcggcagat ggaggtgtgt      120

gtgcgtcacc ctgatgtggc tgcctcagcc atacagggca tccagatcgc catccacgaa      180

tgccaacacc aattcaggga ccagcgctgg aactgctcaa gcctggagac tcgcaacaag      240

atcccctatg agagtcccat cttcagcaga ggtttccgag agagcgcttt tgcctacgcc      300

atcgcagcag ctggcgtggt gcacgccgtg tccaatgcgt gtgccctggg caaactgaag      360

gcctgtggct gtgatgcgtc ccggcgaggg gacgaggagg ccttccgtag gaagctgcac      420

cgcttacaac tggatgcact gcagcgtggt aagggcctga gccatggggt cccggaacac      480

ccagccctgc ccacagccag cccaggcctg caggactcct gggagtgggg cggctgcagc      540

cccgacatgg gcttcgggga gcgcttttct aaggactttc tggactcccg ggagcctcac      600

agagacatcc acgcgagaat gaggcttcac aacaaccgag ttgggaggca ggcagtgatg      660

gagaacatgc ggcggaagtg caagtgccac ggcacgtcag gcagctgcca gctcaagacg      720

tgctggcagg tgacgcccga gttccgcacc gtgggggcgc tgctgcgcag ccgcttccac      780

cgcgccacgc tcatccggcc gcacaaccgc aacggcggcc agctggagcc gggcccagcg      840

ggggcaccct cgccggctcc gggcgctccc gggccgcgcc gacgggccag ccccgccgac      900

ctggtctact tcgaaaagtc tcccgacttc tgcgagcgcg agccgcgcct ggactcggcg      960

ggcaccgtgg gccgcctgtg caacaagagc agcgccggct cggatggctg cggcagcatg     1020

tgctgcggcc gcggccacaa catcctgcgc cagacgcgca gcgagcgctg ccactgccgc     1080

ttccactggt gctgtttcgt ggtctgcgaa gagtgccgca tcaccgagtg ggtcagcgtc     1140

tgcaag                                                                1146


<210>  5989
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  5989
tgtaacaaag cactctgtgc tagtgatgtg agcaaatgcc tcattcagga gctctgccag       60

tgccggccgg gagaaggcaa ttgctcctgc tgtaaggagt gcatgctgtg tcttggggcc      120

ctttgggacg agtgctgtga ctgtgttggt atgtgtaatc ctcgaaatta tagtgacaca      180

cctccaactt caaagagcac agtggaggag ctgcatgaac cgatcccttc tctcttccgg      240

gcactcacag aaggagatac tcagttgaat tggaacatcg tttctttccc tgttgcagaa      300

gaactttcac atcatgagaa tctggtttca tttttagaaa ctgtgaacca gccacaccac      360

cagaatgtgt ctgtccccag caataatgtt cacgcgcctt attccagtga caaagaacac      420

atgtgtactg tggtttattt tgatgactgc atgtccatac atcagtgtaa aatatcctgt      480

gagtccatgg gagcatccaa atatcgctgg tttcataatg cctgctgcga gtgcattggt      540

ccagaatgta ttgactatgg tagtaaaact gtcaaatgta tgaactgcat gttt            594


<210>  5990
<211>  639
<212>  DNA
<213>  Homo Sapiens

<400>  5990
gctgagggcc ggctggctct caagctgttc cgtgacctct ttgccaacta cacaagtgcc       60

ctgagacctg tggcagacac agaccagact ctgaatgtga ccctggaggt gacactgtcc      120

cagatcatcg acatggatga acggaaccag gtgctgaccc tgtatctgtg gatacggcag      180

gagtggacag atgcctacct acgatgggac cccaatgcct atggtggcct ggatgccatc      240

cgcatcccca gcagtcttgt gtggcggcca gacatcgtac tctataacaa agccgacgcg      300

cagcctccag gttccgccag caccaacgtg gtcctgcgcc acgatggcgc cgtgcgctgg      360

gacgcgccgg ccatcacgcg cagctcgtgc cgcgtggatg tagcagcctt cccgttcgac      420

gcccagcact gcggcctgac gttcggctcc tggactcacg gcgggcacca actggatgtg      480

cggccgcgcg gcgctgcagc cagcctggcg gacttcgtgg agaacgtgga gtggcgcgtg      540

ctgggcatgc cggcgcggcg gcgcgtgctc acctacggct gctgctccga gccctacccc      600

gacgtcacct tcacgctgct gttgcgccgc cgcgccgcc                             639


<210>  5991
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  5991
gaagatgcct cctctgactc gacgggtgct gatcctgccc aggaagctgg gacctctaag       60

cctaatgaag agatctcagg tccagcagaa ccagcttcac ccccagagac aaccacaaca      120

gcccaggaga cttcggcggc agcagttcag gggacagcca aagtcacctc aagcaggcag      180

gaactaaacc ccctgaaatc catagtggag aaaagtatct tactaacaga acaagccctt      240

gcaaaagcag gaaaaggaat gcacggaggc gtgccaggtg gaaaacaatt catcgaaaat      300

ggaagtgaat ttgcacaaaa attactgaag aaattcagtc tattaaaacc atgggca         357


<210>  5992
<211>  300
<212>  DNA
<213>  Homo Sapiens

<400>  5992
ctggcgggga ccccggagca ccgctgtcga gtgccggacg ccgcgaacct gagcagcgcc       60

tggcgcaaca acagtgtccc gctgcggctg cgggacggcc gcgaggtgcc ccacagctgc      120

agccgctacc ggctcgccac catcgccaac ttctcggcgc tcgggctgga gccggggcgc      180

gacgtggacc tggggcagct ggagcaggag agctgcctgg atggctggga gttcagccag      240

gacgtctacc tgtccaccgt cgtgaccgag tggaatctgg tgtgtgagga caactggaag      300


<210>  5993
<211>  1425
<212>  DNA
<213>  Homo Sapiens

<400>  5993
tacctcctgc ccaacgtcac tctcttagag gagctgctca gcaaatacca gcacaacgag       60

tctcactccc gggtccgcag agccatcccc agggaggaca aggaggagat cctcatgctg      120

cacaacaagc ttcggggcca ggtgcagcct caggcctcca acatggagta catgacctgg      180

gatgacgaac tggagaagtc tgctgcagcg tgggccagtc agtgcatctg ggagcacggg      240

cccaccagtc tgctggtgtc catcgggcag aacctgggcg ctcactgggg caggtatcgc      300

tctccggggt tccatgtgca gtcctggtat gacgaggtga aggactacac ctacccctac      360

ccgagcgagt gcaacccctg gtgtccagag aggtgctcgg ggcctatgtg cacgcactac      420

acacagatag tttgggccac caccaacaag atcggttgtg ctgtgaacac ctgccggaag      480

atgactgtct ggggagaagt ttgggagaac gcggtctact ttgtctgcaa ttattctcca      540

aaggggaact ggattggaga agccccctac aagaatggcc ggccctgctc tgagtgccca      600

cccagctatg gaggcagctg caggaacaac ttgtgttacc gagaagaaac ctacactcca      660

aaacctgaaa cggacgagat gaatgaggtg gaaacggctc ccattcctga agaaaaccat      720

gtttggctcc aaccgagggt gatgagaccc accaagccca agaaaacctc tgcggtcaac      780

tacatgaccc aagtcgtcag atgtgacacc aagatgaagg acaggtgcaa agggtccacg      840

tgtaacaggt accagtgccc agcaggctgc ctgaaccaca aggcgaagat ctttggaact      900

ctgttctatg aaagctcgtc tagcatatgc cgcgccgcca tccactacgg gatcctggat      960

gacaagggag gcctggtgga tatcaccagg aacgggaagg tccccttctt cgtgaagtct     1020

gagagacacg gcgtgcagtc cctcagcaaa tacaaacctt ccagctcatt catggtgtca     1080

aaagtgaaag tgcaggattt ggactgctac acgaccgttg ctcagctgtg cccgtttgaa     1140

aagccagcaa ctcactgccc aagaatccat tgtccggcac actgcaaaga cgaaccttcc     1200

tactgggctc cggtgtttgg aaccaacatc tatgcagata cctcaagcat ctgcaagaca     1260

gccgtgcacg cgggagtcat cagcaacgag agtgggggtg acgtggacgt gatgcccgtg     1320

gataaaaaga agacctacgt gggctcgctc aggaatggag ttcagtctga aagcctgggg     1380

actcctcggg atggaaaggc cttccggatc tttgctgtca ggcag                     1425


<210>  5994
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  5994
caaagaaaga aggagatggt gttatcagaa aaggttagtc agctgatgga atggactaac       60

aaaagacctg taataagaat gaatggagac aagttccgtc gccttgtgaa agccccaccg      120

agaaattact ccgttatcgt catgttcact gctctccaac tgcatagaca gtgtgtcgtt      180

tgcaagcaag ctgatgaaga attccagatc ctggcaaact cctggcgata ctccagtgca      240

ttcaccaaca ggatattttt tgccatggtg gattttgatg aaggctctga tgtatttcag      300

atgctaaaca tgaattcagc tccaactttc atcaactttc ctgcaaaagg gaaacccaaa      360

cggggtgata catatgagtt acaggtgcgg ggtttttcag ctgagcagat tgcccggtgg      420

atcgccgaca gaactgatgt caatattaga gtgattagac cccca                      465


<210>  5995
<211>  1446
<212>  DNA
<213>  Homo Sapiens

<400>  5995
ccgtgtccag accggccggc gtcacagcga atgtggagga tagactacag tgccgctgtt       60

atctatgact ttctggctgt ggatgatata aacggggaca ggatccaaga tgttcttttt      120

ctttataaaa acaccaacag cagcaacaat ttcagccgat cctgtgtgga cgaaggcttt      180

tcctctccct gcacctttgc agctgctgtg tcgggggcca acggcagcac gctctgggag      240

agacctgtgg cccaagacgt ggccctcgtg gagtgtgctg tgccccagcc aagaggcagt      300

gaggcacctt ctgcctgcat cctggtgggc agacccagtt ctttcattgc agtcaacttg      360

ttcacagggg aaaccctgtg gaaccacagc agcagcttca gcgggaatgc gtccatcctg      420

agccctctgc tgcaggtgcc tgatgtggac ggcgatgggg ccccagacct gctggttctc      480

acccaggagc gggaggaggt tagtggccac ctctactccg gcagcaccgg gcaccagatt      540

ggcctcagag gcagccttgg tgtggacggg gaaagtggct tcctccttca cgtcaccagg      600

acaggtgccc actacatcct ctttccctgc gcaagctccc tctgcggctg ctctgtgaag      660

ggtctctacg agaaggtgac cgggagcggc ggcccgttca agagtgaccc gcactgggag      720

agcatgctca atgccaccac ccgcaggatg ctttcccaca gctctggagc agtgcgctac      780

ctgatgcatg tcccagggaa cgccggtgca gatgtgcttc ttgtgggctc agaggccttc      840

gtgctgctgg acgggcagga gctgacgcct cgctggacac ccaaggcagc ccatgtcctg      900

agaaaaccca tcttcggccg ctacaaacca gacaccttgg ctgtagccgt tgaaaacgga      960

actggcaccg acagacagat cctgtttctg gaccttggca ctggagccgt cctgtgtagc     1020

ctagccctcc cgagcctccc tgggggtcca ctgtccgcca gcctgccgac cgcagaccac     1080

cgctcagcct tcttcttctg gggcctccac gagctgggga gcaccagcga gacggagacc     1140

ggggaggccc ggcacagcct gtacatgttc caccccaccc tgccgcgcgt gctgctggag     1200

ctggccaatg tctctaccca cattgtcgcc tttgacgccg tcctgtttga gccaagccgc     1260

cacgccgcct acatccttct gacaggcccg gcagactcag aggcacccgg cctggtctct     1320

gtgatcaagc acaaggtgcg ggaccttgtc ccaagcagca gggtggtccg cctgggtgag     1380

ggtgggccag acagtgacca agccatcagg gaccggttct cccggctgcg gtaccagagt     1440

gaggcg                                                                1446


<210>  5996
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  5996
aggaagaaaa cctttctaag cgtccatgaa gtgatggcag tagaaaacta tgcgaaggac       60

agcttgcagt ggatcaccga ccagtataac aaggaaagtg atgacaagta ccacttcagg      120

atcttccgag tccttaaagt ccagaggcag gtcactgacc acctggagta tcacctgaac      180

gtggaaatgc agtggaccac ctgccaaaag ccagagacca cgaactgtgt cccccaggaa      240

agggagcttc acaagcaagt caactgcttc ttctcagtgt ttgctgtacc ctggtttgaa      300

cagtacaaaa ttttgaacaa aagctgcagc agtgac                                336


<210>  5997
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  5997
gccaagctgg gtcacttcca aaggtgggag ggcttccagc agaagctcat gagcaagaag       60

aacatgaatt caacactcaa cttcttcatt caatcctaca acaatgccag caacgacacc      120

tacttatatc gagtccagag gctaattcga agtcagatgc agctgacgac gggagtggag      180

tatatagtca ctgtgaagat tggccggacc aaatgcaaga ggaatgacac gagcaattct      240

tcctgccccc tgcaaagcaa gaagctgaga aagagtttaa tttgcgagtc tttgatatac      300

accatgccct ggataaacta tttccagctc tggaacaatt cctgtctgga ggccgagcat      360

gtgggcagaa acctcaga                                                    378


<210>  5998
<211>  1290
<212>  DNA
<213>  Homo Sapiens

<400>  5998
catcagaacc tgaaggagtt tgccctgacc aacccagaga agagcagcac caaagaaacg       60

gagagaaaag aaaccaaagc cgaggaggag ctggatgccg aagtcctgga ggtgttccac      120

ccgacgcatg agtggcaggc ccttcagcca gggcaggctg tccctgcagg atcccacgta      180

cggctgaatc ttcagactgg ggaaagagag gcaaaactcc aatatgagga caagttccga      240

aataatttga aaggcaaaag gctggatatc aacaccaaca cctacacatc tcaggatctc      300

aagagtgcac tggcaaaatt caaggagggg gcagagatgg agagttcaaa ggaagacaag      360

gcaaggcagg ctgaggtaaa gcggctcttc cgccccattg aggaactgaa gaaagacttt      420

gatgagctga atgttgtcat tgagactgac atgcagatca tggtacggct gatcaacaag      480

ttcaatagtt ccagctccag tttggaagag aagattgctg cgctctttga tcttgaatat      540

tatgtccatc agatggacaa tgcgcaggac ctgctttcct ttggtggtct tcaagtggtg      600

atcaatgggc tgaacagcac agagcccctc gtgaaggagt atgctgcgtt tgtgctgggc      660

gctgcctttt ccagcaaccc caaggtccag gtggaggcca tcgaaggggg agccctgcag      720

aagctgctgg tcatcctggc cacggagcag ccgctcactg caaagaagaa ggtcctgttt      780

gcactgtgct ccctgctgcg ccacttcccc tatgcccagc ggcagttcct gaagctcggg      840

gggctgcagg tcctgaggac cctggtgcag gagaagggca cggaggtgct cgccgtgcgc      900

gtggtcacac tgctctacga cctggtcacg gagaagatgt tcgccgagga ggaggctgag      960

ctgacccagg agatgtcccc agagaagctg cagcagtatc gccaggtaca cctcctgcca     1020

ggcctgtggg aacagggctg gtgcgagatc acggcccacc tcctggcgct gcccgagcat     1080

gatgcccgtg agaaggtgct gcagacactg ggcgtcctcc tgaccacctg ccgggaccgc     1140

taccgtcagg acccccagct cggcaggaca ctggccagcc tgcaggctga gtaccaggtg     1200

ctggccagcc tggagctgca ggatggtgag gacgagggct acttccagga gctgctgggc     1260

tctgtcaaca gcttgctgaa ggagctgaga                                      1290


<210>  5999
<211>  900
<212>  DNA
<213>  Homo Sapiens

<400>  5999
cggaggatgt ggacgctgcg gagcccgctc acccgctccc tgtacgtgaa catgactagc       60

ggcccgggtg ggccggcggc ggccgcgggc ggcaggaagg agaaccacca gtggtatgtg      120

tgcaacagag agaaattatg cgaatcactc caggctgtct ttgttcagag ttaccttgat      180

caaggaacac agatcttctt aaacaacagc attgagaaat cgggctggct atttatccaa      240

ttatatcatt cttttgtgtc atctgttttt agcctgttta tgtctagaac atctatcaat      300

gggttgctag gaagaggctc aatgtttgtg ttttcaccag atcagtttca gagactgctt      360

aaaattaatc cagactggaa aacccacaga cttcttgatt taggtgctgg agatggagaa      420

gtcacaaaaa tcatgagccc tcattttgaa gaaatctatg ccactgagct ttctgaaact      480

atgatatggc agcttcagaa aaagaaatac agagtccttg gtataaatga atggcagaat      540

acggggttcc agtatgatgt catcagctgc ctgaacttgc tggaccgctg tgatcagccc      600

ctgactttgt taaaagatat cagaagtgtc ttggagccaa ctagaggcag ggtcatcctt      660

gcccttgtcc tcccctttca tccctatgtg gaaaacgtag gtggcaagtg ggagaaacca      720

tcagaaattt tggaaatcaa aggacagaac tgggaagaac aagtgaatag tctgcctgaa      780

gttttcagaa aagctggttt tgttatcgaa gctttcacca gactaccata cctgtgtgaa      840

ggcgacatgt ataatgacta ctacgttctg gatgacgctg tctttgttct caaaccagta      900


<210>  6000
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  6000
aagcccaagg gcatgacctc atcacagtgg tttaaaattc agcacatgca gcccagccct       60

caagcatgca actcagccat gaaaaacatt aacaagcaca caaaacggtg caaagacctc      120

aacaccttcc tgcacgagcc tttctccagt gtggccgcca cctgccagac ccccaaaata      180

gcctgcaaga atggcgataa aaactgccac cagagccacg ggcccgtgtc cctgaccatg      240

tgtaagctca cctcagggaa gtatccgaac tgcaggtaca aagagaagcg acagaacaag      300

tcttacgtag tggcctgtaa gcctccccag aaaaaggact ctcagcaatt ccacctggtt      360

cctgtacact tggacagagt cctt                                             384


<210>  6001
<211>  174
<212>  DNA
<213>  Homo Sapiens

<400>  6001
ggataccgtg acaagaagag gatgcagaaa acacagctat ccccagaaat caaagtctgc       60

cagcagcagc ctaaactata tctatgcaaa cacttatgtg aatctcaccg agattgtcaa      120

gcaaataaca tatgctgttc tacctactgt gggaatgttt gcatgagcat cctg            174


<210>  6002
<211>  1026
<212>  DNA
<213>  Homo Sapiens

<400>  6002
cagcttctga cagacgccaa ctcctggtgg tcattagctt tgaacccggt gcagagaccc       60

gagatgttta tcatcggtgc ccagcccgtg tgcagtcagc ttcccgggct ctcccctggc      120

cagaggaagc tgtgccaatt gtaccaggag cacatggcct acatagggga gggagccaag      180

actggcatca aggaatgcca gcaccagttc cggcagcggc ggtggaattg cagcacagcg      240

gacaacgcat ctgtctttgg gagagtcatg cagataggca gccgagagac cgccttcacc      300

cacgcggtga gcgccgcggg cgtggtcaac gccatcagcc gggcctgccg cgagggcgag      360

ctctccacct gcggctgcag ccggacggcg cggcccaagg acctgccccg ggactggctg      420

tggggcggct gtggggacaa cgtggagtac ggctaccgct tcgccaagga gtttgtggat      480

gcccgggagc gagagaagaa ctttgccaaa ggatcagagg agcagggccg ggtgctcatg      540

aacctgcaaa acaacgaggc cggtcgcagg gctgtgtata agatggcaga cgtagcctgc      600

aaatgccacg gcgtctcggg gtcctgcagc ctcaagacct gctggctgca gctggccgag      660

ttccgcaagg tcggggaccg gctgaaggag aagtacgaca gcgcggccgc catgcgcgtc      720

acccgcaagg gccggctgga gctggtcaac agccgcttca cccagcccac cccggaggac      780

ctggtctatg tggaccccag ccccgactac tgcctgcgca acgagagcac gggctccctg      840

ggcacgcagg gccgcctctg caacaagacc tcggagggca tggatggctg tgagctcatg      900

tgctgcgggc gtggctacaa ccagttcaag agcgtgcagg tggagcgctg ccactgcaag      960

ttccactggt gctgcttcgt caggtgtaag aagtgcacgg agatcgtgga ccagtacatc     1020

tgtaaa                                                                1026


<210>  6003
<211>  492
<212>  DNA
<213>  Homo Sapiens

<400>  6003
gaatttattg gcttgagacg ctgtttaatg ggtttgggga gatgcaggga tcactgcaat       60

gtggatgaaa aagagataca gaaatgcaag atgaaaaaat gttgtgttgg accaaaagtg      120

gttaaattga ttaaaaacta cctacaatat ggaacaccaa atgtacttaa tgaagacgtc      180

caagaaatgc taaaacctgc caagaattct agtgctgtga tacaaagaaa acatatttta      240

tctgttctcc cccaaatcaa aagcactagc ttttttgcta ataccaactt tgtcatcatt      300

ccaaatgcca cccctatgaa ctctgccacc atcagcacta tgaccccagg acagatcaca      360

tacactgcta cttctaccaa gagtaacacc aaagaaagca gagattctgc cactgcctcg      420

ccaccaccag caccacctcc accaaacata ctgccaacac catcactgga gctagaggaa      480

gcagaagagc ag                                                          492


<210>  6004
<211>  192
<212>  DNA
<213>  Homo Sapiens

<400>  6004
aagcggcagc tgtgggaccg gactcggccc gaggtgcagc agtggtacca gcagtttctc       60

tacatgggct ttgacgaagc gaaatttgaa gatgacatca cctattggct taacagagat      120

cgaaatggac atgaatacta tggcgattac taccaacgtc actatgatga agactctgca      180

attggtcccc gg                                                          192


<210>  6005
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  6005
atgataaact tgagcagcct gtggacagtg cccgcgtgga tttccaaagt gtccttcctg       60

cggtggtgtt ttgaagggct gatgaagatt cagttcagca gaagaactta taaaatgcct      120

ctcgggaacc tcaccatcgc ggtctcagga gataaaatcc tcagtgccat ggagctggac      180

tcgtaccct                                                              189


<210>  6006
<211>  288
<212>  DNA
<213>  Homo Sapiens

<400>  6006
ggcttcaaag caaatgtcat aaatgagaaa tgcattacac aaaattcaga gacgatcatg       60

aaatttttga aaatggggaa cattagtcag gatattattc cccatcatat caacctttca      120

actgttactg cagaagatta tcatttagtt tatgacatca ttcaaaaagt gaaagaagaa      180

gagtttcctg ctcttcatct caattcctgt aaaattgaag aagagctaaa taaagctgtt      240

caggggaccg gcttagcttt tattgccttt acagaagcga tgacacat                   288


<210>  6007
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  6007
ttgctggaag gtgacgagtg tgcaccccac tcccagccat ggcaagtggc tctctacgag       60

cgtggacgct ttaactgtgg cgcttccctc atctccccac actgggtgct gtctgcggca      120

cactgccaaa gccgcttcat gagagtgcgc ctgggagagc acaacctgcg caagcgcgat      180

ggcccagagc aactacggac cacgtctcgg gtcattccac acccgcgcta cgaagcgcgc      240

agccaccgca acgacatcat gttgctgcgc ctagtccagc ccgcacgcct gaacccccag      300

gtgcgccccg cggtgctacc cacgcgttgc ccccacccgg gggaggcctg tgtggtgtct      360

ggctggggcc tggtgtccca caacgagcct gggaccgctg ggagcccccg gtcacaagtg      420

agtctcccag atacgttgca ttgtgccaac atcagcatta tctcggacac atcttgtgac      480

aagagctacc cagggcgcct gacaaacacc atggtgtgtg caggcgcgga gggcagaggc      540

gcagaatcct gtgagggtga ctctggggga cccctggtct gtgggggcat cctgcagggc      600

attgtgtcct ggggtgacgt cccttgtgac aacaccacca agcctggtgt ctataccaaa      660

gtctgccact acttggagtg gatcagggaa accatgaaga ggaac                      705


<210>  6008
<211>  1476
<212>  DNA
<213>  Homo Sapiens

<400>  6008
agaaaaactg ttccagggga taatgaatct gaagaagact ccaaaataaa aggcatccat       60

gatgaaaagt atgttgaatt gttcattgtt gctgatgata ctgtgtatcg cagaaatggt      120

catcctcaca ataaactaag gaaccgaatt tggggaatgg tcaattttgt caacatgatt      180

tataaaacct taaacatcca tgtgacgttg gttggcattg aaatatggac acatgaagat      240

aaaatagaac tatattcaaa tatagaaact accttattgc gtttttcatt ttggcaagaa      300

aagatcctta aaacacggaa ggattttgat catgttgtat tactcagtgg gaagtggctc      360

tactcacatg tgcaaggaat ttcttatcca gggggtatgt gcctgcccta ttattccacc      420

agtatcatta aggatctttt acctgacaca aacataattg caaacagaat ggcacatcaa      480

ctggggcata accttgggat gcagcatgac gagttcccat gcacctgtcc ttcaggaaaa      540

tgcgtgatgg acagtgatgg aagcattcct gcactgaaat tcagtaaatg cagccaaaac      600

caataccacc agtacttgaa ggattataag ccaacatgca tgctcaacat tccatttcct      660

tacaattttc atgatttcca attttgtgga aacaagaagt tggatgaggg tgaagagtgt      720

gactgtggcc ctgctcagga gtgtactaat ccttgctgtg atgcacacac atgtgtactg      780

aagccaggat ttacttgtgc agaaggagaa tgctgtgaat cttgtcagat aaaaaaagca      840

gggtccatat gcagaccggc gaaagatgaa tgtgattttc ctgagatgtg cactggccac      900

tcgcctgcct gtcctaagga ccagttcagg gtcaatggat ttccttgcaa gaactcagaa      960

ggctactgtt tcatggggaa atgtccaact cgtgaggatc agtgctctga actatttgat     1020

gatgaggcaa tagagagtca tgatatctgc tacaagatga atacaaaagg aaataaattt     1080

ggatactgca aaaacaagga aaacagattt cttccctgtg aggagaaaga tgtcagatgt     1140

ggaaagatct actgcactgg aggggagctt tcctctctcc ttggagaaga caagacttat     1200

caccttaagg atccccagaa gaatgctact gtcaaatgca aaactatttt tttataccat     1260

gattctacag acattggcct ggtggcgtca ggaacaaaat gtggagaggg aatggtgtgc     1320

aacaatggtg aatgtctaaa catggaaaag gtctatatct caaccaattg cccctctcag     1380

tgcaatgaaa atcctgtgga tggccacgga ctccagtgcc actgtgagga aggacaggca     1440

cctgtagcct gtgaagaaac cttacatgtt accaat                               1476


<210>  6009
<211>  1245
<212>  DNA
<213>  Homo Sapiens

<400>  6009
tatggctaca ccctccctgg gtggagaaaa tacaacctca cctacagaat aataaactat       60

actccggata tggcacgagc tgctgtggat gaggctatcc aagaaggttt agaagtgtgg      120

agcaaagtca ctccactaaa attcaccaag atttcaaagg ggattgcaga catcatgatt      180

gcctttagga ctcgagtcca tggtcggtgt cctcgctatt ttgatggtcc cttgggagtg      240

cttggccatg cctttcctcc tggtccgggt ctgggtggtg acactcattt tgatgaggat      300

gaaaactgga ccaaggatgg agcaggattc aacttgtttc ttgtggctgc tcatgaattt      360

ggtcatgcac tggggctctc tcactccaat gatcaaacag ccttgatgtt cccaaattat      420

gtctccctgg atcccagaaa atacccactt tctcaggatg atatcaatgg aatccagtcc      480

atctatggag gtctgcctaa ggaacctgct aagccaaagg aacccactat accccatgcc      540

tgtgaccctg acttgacttt tgacgctatc acaactttcc gcagagaagt aatgttcttt      600

aaaggcaggc acctatggag gatctattat gatatcacgg atgttgagtt tgaattaatt      660

gcttcattct ggccatctct gccagctgat ctgcaagctg catacgagaa ccccagagat      720

aagattctgg tttttaaaga tgaaaacttc tggatgatca gaggatatgc tgtcttgcca      780

gattatccca aatccatcca tacattaggt tttccaggac gtgtgaagaa aatagatgca      840

gccgtctgtg ataagaccac aagaaaaacc tacttctttg tgggcatttg gtgctggagg      900

tttgatgaaa tgacccaaac catggacaaa gggttcccgc agagagtggt aaaacacttt      960

cctggaatca gtatccgtgt tgatgctgct ttccagtaca aaggattctt ctttttcagc     1020

cgtggatcaa agcaatttga atacgacatt aagacaaaga atattacccg aatcatgaga     1080

actaatactt ggtttcaatg caaagaacca aagaactcct catttggttt tgatatcaac     1140

aaggaaaaag cacattcagg aggcataaag atattgtatc ataagagttt aagcttgttt     1200

atttttggta ttgttcattt gctgaaaaac acttctattt atcaa                     1245


<210>  6010
<211>  1431
<212>  DNA
<213>  Homo Sapiens

<400>  6010
atggtggttc ccaatgccac tttattggag aaacttttgg aaaaatacat ggatgaggat       60

ggtgagtggt ggatagccaa acaacgaggg aaaagggcca tcacagacaa tgacatgcag      120

agtattttgg accttcataa taaattacga agtcaggtgt atccaacagc ctctaatatg      180

gagtatatga catgggatgt agagctggaa agatctgcag aatcctgggc tgaaagttgc      240

ttgtgggaac atggacctgc aagcttgctt ccatcaattg gacagaattt gggagcacac      300

tggggaagat ataggccccc gacgtttcat gtacaatcgt ggtatgatga agtgaaagac      360

tttagctacc catatgaaca tgaatgcaac ccatattgtc cattcaggtg ttctggccct      420

gtatgtacac attatacaca ggtcgtgtgg gcaactagta acagaatcgg ttgtgccatt      480

aatttgtgtc ataacatgaa catctggggg cagatatggc ccaaagctgt ctacctggtg      540

tgcaattact ccccaaaggg aaactggtgg ggccatgccc cttacaaaca tgggcggccc      600

tgttctgctt gcccacctag ttttggaggg ggctgtagag aaaatctgtg ctacaaagaa      660

gggtcagaca ggtattatcc ccctcgagaa gaggaaacaa atgaaataga acgacagcag      720

tcacaagtcc atgacaccca tgtccggaca agatcagatg atagtagcag aaatgaagtc      780

ataagcgcac agcaaatgtc ccaaattgtt tcttgtgaag taagattaag agatcagtgc      840

aaaggaacaa cctgcaatag gtacgaatgt cctgctggct gtttggatag taaagctaaa      900

gttattggca gtgtacatta tgaaatgcaa tccagcatct gtagagctgc aattcattat      960

ggtataatag acaatgatgg tggctgggta gatatcacta gacaaggaag aaagcattat     1020

ttcatcaagt ccaatagaaa tggtattcaa acaattggca aatatcagtc tgctaattcc     1080

ttcacagtct ctaaagtaac agttcaggct gtgacttgtg aaacaactgt ggaacagctc     1140

tgtccatttc ataagcctgc ttcacattgc ccaagagtat actgtcctcg taactgtatg     1200

caagcaaatc cacattatgc tcgtgtaatt ggaactcgag tttattctga tctgtccagt     1260

atctgcagag cagcagtaca tgctggagtg gttcgaaatc acggtggtta tgttgatgta     1320

atgcctgtgg acaaaagaaa gacctacatt gcttcttttc agaatggaat cttctcagaa     1380

agtttacaga atcctccagg aggaaaggca ttcagagtgt ttgctgttgt g              1431


<210>  6011
<211>  1362
<212>  DNA
<213>  Homo Sapiens

<400>  6011
ctgtttcgct ccctatacag aagtgtttcc atgccaccta agggagactc aggacagcca       60

ttatttctca ccccttacat tgaagctggg aagatccaaa aaggaagaga attgagtttg      120

gtcggccctt tcccaggact gaacatgaag agttatgccg gcttcctcac cgtgaataag      180

acttacaaca gcaacctctt cttctggttc ttcccagctc agatacagcc agaagatgcc      240

ccagtagttc tctggctaca gggtgggccg ggaggttcat ccatgtttgg actctttgtg      300

gaacatgggc cttatgttgt cacaagtaac atgaccttgc gtgacagaga cttcccctgg      360

accacaacgc tctccatgct ttacattgac aatccagtgg gcacaggctt cagttttact      420

gatgataccc acggatatgc agtcaatgag gacgatgtag cacgggattt atacagtgca      480

ctaattcagt ttttccagat atttcctgaa tataaaaata atgactttta tgtcactggg      540

gagtcttatg cagggaaata tgtgccagcc attgcacacc tcatccattc cctcaaccct      600

gtgagagagg tgaagatcaa cctgaacgga attgctattg gagatggata ttctgatccc      660

gaatcaatta tagggggcta tgcagaattc ctgtaccaaa ttggcttgtt ggatgagaag      720

caaaaaaagt acttccagaa gcagtgccat gaatgcatag aacacatcag gaagcagaac      780

tggtttgagg cctttgaaat actggataaa ctactagatg gcgacttaac aagtgatcct      840

tcttacttcc agaatgttac aggatgtagt aattactata actttttgcg gtgcacggaa      900

cctgaggatc agctttacta tgtgaaattt ttgtcactcc cagaggtgag acaagccatc      960

cacgtgggga atcagacttt taatgatgga actatagttg aaaagtactt gcgagaagat     1020

acagtacagt cagttaagcc atggttaact gaaatcatga ataattataa ggttctgatc     1080

tacaatggcc aactggacat catcgtggca gctgccctga cagagcgctc cttgatgggc     1140

atggactgga aaggatccca ggaatacaag aaggcagaaa aaaaagtttg gaagatcttt     1200

aaatctgaca gtgaagtggc tggttacatc cggcaagtgg gtgacttcca tcaggtaatt     1260

attcgaggtg gaggacatat tttaccctat gaccagcctc tgagagcttt tgacatgatt     1320

aatcgattca tttatggaaa aggatgggat ccttatgttg ga                        1362


<210>  6012
<211>  462
<212>  DNA
<213>  Homo Sapiens

<400>  6012
cggcggagca acgttcgcgt catcacggac gagaactgga gagaactgct ggaaggagac       60

tggatgatag aattttatgc cccgtggtgc cctgcttgtc aaaatcttca accggaatgg      120

gaaagttttg ctgaatgggg agaagatctt gaggttaata ttgcgaaagt agatgtcaca      180

gagcagccag gactgagtgg acggtttatc ataactgctc ttcctactat ttatcattgt      240

aaagatggtg aatttaggcg ctatcagggt ccaaggacta agaaggactt cataaacttt      300

ataagtgata aagagtggaa gagtattgag cccgtttcat catggtttgg tccaggttct      360

gttctgatga gtagtatgtc agcactcttt cagctatcta tgtggatcag gacgtgccat      420

aactacttta ttgaagacct tggattgcca gtgtggggat ca                         462


<210>  6013
<211>  1161
<212>  DNA
<213>  Homo Sapiens

<400>  6013
tatctgtgtc ctgctgcctc tcagcccatt tccgggacct tgcaggatga ggagataact       60

ttgagctgct cagaggccag cgctgaggaa gctctgctcc ctgcacttcc caaaacagta      120

tctttcagaa taaacagcga agacttcttg ctggaagcgc aagtgaggga tcagccacgc      180

tggctcctgg tctgccatga gggctggagc cccgccctgg ggctgcagat ctgctggagc      240

cttgggcatc tcagactcac tcaccacaag ggagtaaacc tcactgacat caaactcaac      300

agttcccagg agtttgctca gctctctcct agactgggag gcttcctgga ggaggcgtgg      360

cagcccagga acaactgcac ttctggtcaa gttgtttccc tcagatgctc tgagtgtgga      420

gcgaggcccc tggcttcccg gatagttggt gggcagtctg tggctcctgg gcgctggccg      480

tggcaggcca gcgtggccct gggcttccgg cacacgtgtg ggggctctgt gctagcgcca      540

cgctgggtgg tgactgctgc acattgtatg cacagtttca ggctggcccg cctgtccagc      600

tggcgggttc atgcggggct ggtcagccac agtgccgtca ggccccacca aggggctctg      660

gtggagagga ttatcccaca ccccctctac agtgcccaga atcatgacta cgacgtcgcc      720

ctcctgaggc tccagaccgc tctcaacttc tcagacactg tgggcgctgt gtgcctgccg      780

gccaaggaac agcattttcc gaagggctcg cggtgctggg tgtctggctg gggccacacc      840

caccctagcc atacttacag ctcggatatg ctccaggaca cggtggtgcc cctgctcagc      900

actcagctct gcaacagctc ttgcgtgtac agcggagccc tcaccccccg catgctttgc      960

gctggctacc tggacggaag ggctgatgca tgccagggag atagcggggg ccccctagtg     1020

tgcccagatg gggacacatg gcgcctagtg ggggtggtca gctgggggcg tggctgcgca     1080

gagcccaatc acccaggtgt ctacgccaag gtagctgagt ttctggactg gatccatgac     1140

actgctcagg actccctcct c                                               1161


<210>  6014
<211>  1275
<212>  DNA
<213>  Homo Sapiens

<400>  6014
cagaagttct cggcgctcac gtttttgaga gtggatcaag ataaagacaa ggattgtagc       60

ttggactgtg cgggttcgcc ccagaaacct ctctgcgcat ctgacggaag gaccttcctt      120

tcccgttgtg aatttcaacg tgccaagtgc aaagatcccc agctagagat tgcatatcga      180

ggaaactgca aagacgtgtc caggtgtgtg gccgaaagga agtataccca ggagcaagcc      240

cggaaggagt ttcagcaagt gttcattcct gagtgcaatg acgacggcac ctacagtcag      300

gtccagtgtc acagctacac gggatactgc tggtgcgtca cgcccaacgg gaggcccatc      360

agcggcactg ccgtggccca caagacgccc cggtgcccgg gttccgtaaa tgaaaagtta      420

ccccaacgcg aaggcacagg aaaaacagat gatgccgcag ctccagcgtt ggagactcag      480

cctcaaggag atgaagaaga tattgcatca cgttacccta ccctttggac tgaacaggtt      540

aaaagtcggc agaacaaaac caataagaat tcagtgtcat cctgtgacca agagcaccag      600

tctgccctgg aggaagccaa gcagcccaag aacgacaatg tggtgatccc tgagtgtgcg      660

cacggcggcc tctacaagcc agtgcagtgc cacccctcca cggggtactg ctggtgcgtc      720

ctggtggaca cggggcgccc cattcccggc acatccacaa ggtacgagca gccgaaatgt      780

gacaacacgg ccagggccca cccagccaaa gcccgggacc tgtacaaggg ccgccagcta      840

caaggttgtc cgggtgccaa aaagcatgag tttctgacca gcgttctgga cgcgctgtcc      900

acggacatgg tccacgccgc ctccgacccc tcctcctcgt caggcaggct ctcagaaccc      960

gaccccagcc ataccctaga ggagcgggtg gtgcactggt acttcaaact actggataaa     1020

aactccagtg gagacatcgg caaaaaggaa atcaaaccct tcaagaggtt ccttcgcaaa     1080

aaatcaaagc ccaaaaaatg tgtgaagaag tttgttgaat actgtgacgt gaataatgac     1140

aaatccatct ccgtacaaga actgatgggc tgcctgggcg tggcgaaaga ggacggcaaa     1200

gcggacacca agaaacgcca cacccccaga ggtcatgttg aaagtacgtc taatagacag     1260

ccaaggaaac aagga                                                      1275


<210>  6015
<211>  591
<212>  DNA
<213>  Homo Sapiens

<400>  6015
cacatctctg tgagagacat gaatgcctta ctggattatc acaaccacat ccgggccagt       60

gtgtacccac ctgccgccaa catggaatac atggtctggg acaagcggct ggccagggct      120

gccgaagcct gggccaccca gtgcatctgg gcacatgggc cttcacagct gatgagatac      180

gtgggccaga acctctccat ccattctggc cagtaccggt ccgtagtgga tctcatgaag      240

tcctggtctg aggagaagtg gcattacttg tttccggccc caagggactg taacccacac      300

tgcccctggc gctgcgatgg ccccacctgc tcccattata cccagatggt gtgggcatcc      360

tccaatcggc tgggctgtgc catccacacc tgtagtagca tcagtgtctg gggcaacacc      420

tggcatcggg cggcatacct ggtctgcaac tatgccatta agggcaactg gattggcgag      480

tccccgtaca agatgggaaa gccgtgctcc tcctgtcccc ccagttatca aggcagctgc      540

aatagcaaca tgtgcttcaa ggggctgaaa tccaacaagt tcacgtggtt c               591


<210>  6016
<211>  744
<212>  DNA
<213>  Homo Sapiens

<400>  6016
gcctcggcca aggagctggc atgccaagag atcaccgtgc cgctgtgtaa gggcatcggc       60

tacaactaca cctacatgcc caatcagttc aaccacgaca cgcaagacga ggcgggcctg      120

gaggtgcacc agttctggcc gctggtggag atccagtgct cgcccgatct caagttcttc      180

ctgtgcagca tgtacacgcc catctgccta gaggactaca agaagccgct gccgccctgc      240

cgctcggtgt gcgagcgcgc caaggccggc tgcgcgccgc tcatgcgcca gtacggcttc      300

gcctggcccg accgcatgcg ctgcgaccgg ctgcccgagc aaggcaaccc tgacacgctg      360

tgcatggact acaaccgcac cgacctaacc accgccgcgc ccagcccgcc gcgccgcctg      420

ccgccgccgc cgcccggcga gcagccgcct tcgggcagcg gccacggccg cccgccgggg      480

gccaggcccc cgcaccgcgg cggcggcagg ggcggtggcg gcggggacgc ggcggcgccc      540

ccagctcgcg gcggcggcgg tggcgggaag gcgcggcccc ctggcggcgg cgcggctccc      600

tgcgagcccg ggtgccagtg ccgcgcgcct atggtgagcg tgtccagcga gcgccacccg      660

ctctacaacc gcgtcaagac aggccagatc gctaactgcg cgctgccctg ccacaacccc      720

tttttcagcc aggacgagcg cgcc                                             744


<210>  6017
<211>  1116
<212>  DNA
<213>  Homo Sapiens

<400>  6017
gcctccaggc cgtgggaggg aaccgacgag ccgggctcgg cctgggcctg gccgggcttc       60

cagcgcctgc aggagcagct cagggcggcg ggtgccctct ccaagcggta ctggacgctc      120

ttcagctgcc aggtgtggcc cgacgactgt gacgaggacg aggaggcagc cacggggccc      180

ctgggctggc gccttcctct gttgggccag cggtacctgg acctcctgac cacgtggtac      240

tgcagcttca aagactgctg ccctagaggg gattgcagaa tctccaacaa ctttacaggc      300

ttagagtggg acctgaatgt gcggctgcat ggccagcatt tggtccagca gctggtccta      360

agaacagtga ggggctactt agagacgccc cagccagaaa aggcccttgc tctgtcgttc      420

cacggctggt ctggcacagg caagaacttc gtggcacgga tgctggtgga gaacctgtat      480

cgggacgggc tgatgagtga ctgtgtcagg atgttcatcg ccacgttcca ctttcctcac      540

cccaaatatg tggacctgta caaggagcag ctgatgagcc agatccggga gacgcagcag      600

ctctgccacc agaccctgtt catcttcgat gaagcggaga agctgcaccc agggctgctg      660

gaggtccttg ggccacactt agaacgccgg gcccctgagg gccacagggc tgagtctcca      720

tggactatct ttctgtttcc cagtaatctc aggggcgata taatcaatga ggtggtccta      780

aagttgctca aggctggatg gtcccgggaa gaaattacga tggaacacct ggagccccac      840

ctccaggcgg agattgtgga gaccatagac aatggctttg gccacagccg tcttgtgaag      900

gaaaacctga ttgactactt catccccttc ctgcctttgg agtaccgtca cgtgaggctg      960

tgtgcacggg atgccttcct gagccaggag ctcctgtata aagaagagac actggatgaa     1020

atagcccaga tgatggtgta tgtccccaag gaggaacaac tcttttcttc ccagggctgc     1080

aagtctattt cccagaggat taactacttc ctgtca                               1116


<210>  6018
<211>  1947
<212>  DNA
<213>  Homo Sapiens

<400>  6018
gcgagcggcg agcattcccc cggcagcggc gcggcccggc ggccgctgca ctccgcgcag       60

gctgtggacg tggcctcggc ctccaacttc cgggcctttg agctgctgca cttgcacctg      120

gacctgcggg ctgagttcgg gcctccaggg cccggcgcag ggagccgggg gctgagcggc      180

accgcggtcc tggacctgcg ctgcctggag cccgagggcg ccgccgagct gcggctggac      240

tcgcacccgt gcctggaggt gacggcggcg gcgctgcggc gggagcggcc cggctcggag      300

gagccgcctg cggagcccgt gagcttctac acgcagccct tctcgcacta tggccaggcc      360

ctgtgcgtgt ccttcccgca gccctgccgc gccgccgagc gcctccaggt gctgctcacc      420

taccgcgtcg gggagggacc cggggtttgc tggttggctc ccgagcagac agcaggaaag      480

aagaagccct tcgtgtacac ccagggccag gctgtcctaa accgggcctt cttcccttgc      540

ttcgacacgc ctgctgttaa atacaagtat tcagctctta ttgaggtccc agatggcttc      600

acagctgtga tgagtgctag cacctgggag aagagaggtc caaataagtt cttcttccag      660

atgtgtcagc ccatcccctc ctatctgata gctttggcca tcggagatct ggtttcggct      720

gaagttggac ccaggagccg ggtgtgggct gagccctgcc tgattgatgc tgccaaggag      780

gagtacaacg gggtgataga agaatttttg gcaacaggag agaagctttt tggaccttat      840

gtttggggaa ggtatgactt gctcttcatg ccaccgtcct ttccatttgg aggaatggag      900

aacccttgtc tgacctttgt caccccctgc ctgctagctg gggaccgctc cttggcagat      960

gtcatcatcc atgagatctc ccacagttgg tttgggaacc tggtcaccaa cgccaactgg     1020

ggtgaattct ggctcaatga aggtttcacc atgtacgccc agaggaggat ctccaccatc     1080

ctctttggcg ctgcgtacac ctgcttggag gctgcaacgg ggcgggctct gctgcgtcaa     1140

cacatggaca tcactggaga ggaaaaccca ctcaacaagc tccgcgtgaa gattgaacca     1200

ggcgttgacc cggacgacac ctataatgag accccctacg agaaaggttt ctgctttgtc     1260

tcatacctgg cccacttggt gggtgatcag gatcagtttg acagttttct caaggcctat     1320

gtgcatgaat tcaaattccg aagcatctta gccgatgact ttctggactt ctacttggaa     1380

tatttccctg agcttaagaa aaagagagtg gatatcattc caggttttga gtttgatcga     1440

tggctgaata cccccggctg gcccccgtac ctccctgatc tctcccctgg ggactcactc     1500

atgaagcctg ctgaagagct agcccaactg tgggcagccg aggagctgga catgaaggcc     1560

attgaagccg tggccatctc tccctggaag acctaccagc tggtctactt cctggataag     1620

atcctccaga aatcccctct ccctcctggg aatgtgaaaa aacttggaga cacataccca     1680

agtatctcaa atgcccggaa tgcagagctc cggctgcgat ggggccaaat cgtccttaag     1740

aacgaccacc aggaagattt ctggaaagtg aaggagttcc tgcataacca ggggaagcag     1800

aagtatacac ttccgctgta ccacgcaatg atgggtggca gtgaggtggc ccagaccctc     1860

gccaaggaga cttttgcatc caccgcctcc cagctccaca gcaatgttgt caactatgtc     1920

cagcagatcg tggcacccaa gggcagt                                         1947


<210>  6019
<211>  1281
<212>  DNA
<213>  Homo Sapiens

<400>  6019
gcggagacca cgccgggcgc ccccagagcc ctctccctgg gctcccccag cctcttcacc       60

acgccgggtg tccccagcgc cctcactacc ccaggcctca ctacgccagg cacccccaaa      120

accctggacc ttcggggtcg cgcgcaggcc ctgatgcgga gtttcccact cgtggacggc      180

cacaatgacc tgccccaggt cctgagacag cgttacaaga atgtgcttca ggatgttaac      240

ctgcgaaatt tcagccatgg tcagaccagc ctggacaggc ttagagacgg cctcgtgggt      300

gcccagttct ggtcagcctc cgtctcatgc cagtcccagg accagactgc cgtgcgcctc      360

gccctggagc agattgacct cattcaccgc atgtgtgcct cctactctga actcgagctt      420

gtgacctcag ctgaaggtct gaacagctct caaaagctgg cctgcctcat tggcgtggag      480

ggtggtcact cactggacag cagcctctct gtgctgcgca gtttctatgt gctgggggtg      540

cgctacctga cacttacctt cacctgcagt acaccatggg cagagagttc caccaagttc      600

agacaccaca tgtacaccaa cgtcagcgga ttgacaagct ttggtgagaa agtagtagag      660

gagttgaacc gcctgggcat gatgatagat ttgtcctatg catcggacac cttgataaga      720

agggtcctgg aagtgtctca ggctcctgtg atcttctccc actcagctgc cagagctgtg      780

tgtgacaatt tgttgaatgt tcccgatgat atcctgcagc ttctgaagaa gaacggtggc      840

atcgtgatgg tgacactgtc catgggggtg ctgcagtgca acctgcttgc taacgtgtcc      900

actgtggcag atcactttga ccacatcagg gcagtcattg gatctgagtt catcgggatt      960

ggtggaaatt atgacgggac tggccggttc cctcaggggc tggaggatgt gtccacatac     1020

ccagtcctga tagaggagtt gctgagtcgt agctggagcg aggaagagct tcaaggtgtc     1080

cttcgtggaa acctgctgcg ggtcttcaga caagtggaaa aggtgagaga ggagagcagg     1140

gcgcagagcc ccgtggaggc tgagtttcca tatgggcaac tgagcacatc ctgccactcc     1200

cacctcgtgc ctcagaatgg acaccaggct actcatctgg aggtgaccaa gcagccaacc     1260

aatcgggtcc cctggaggtc c                                               1281


<210>  6020
<211>  2433
<212>  DNA
<213>  Homo Sapiens

<400>  6020
agcggcggtg gcggggacag ccggcagcgc cgcctcctcg cggctaaagt caataagcac       60

aagccatgga tcgagacttc atatcatgga gtcataactg agaacaatga cacagtcatt      120

ttggacccac cactggtagc cctggataaa gatgcaccgg ttccttttgc aggggaaatc      180

tgtgcgttca agatccatgg ccaggagctg ccctttgagg ctgtggtgct caacaagaca      240

tcaggagagg gccggctccg tgccaagagc cccattgact gtgagttgca gaaggagtac      300

acattcatca tccaggccta tgactgtggt gctgggcccc acgagacagc ctggaaaaag      360

tcacacaagg ccgtggtcca tatacaggtg aaggatgtca acgagtttgc tcccaccttc      420

aaagagccag cctacaaggc tgttgtgacg gagggcaaga tctatgacag cattctgcag      480

gtggaggcca ttgacgagga ctgctcccca cagtacagcc agatctgcaa ctatgaaatc      540

gtcaccacag atgtgccttt tgccatcgac agaaatggca acatcaggaa cactgagaag      600

ctgagctatg acaaacaaca ccagtatgag atcctggtga ccgcctacga ctgtggacag      660

aagcccgctg ctcaggacac cctggtgcag gtggatgtga agccagtttg caagcctggc      720

tggcaagact ggaccaagag gattgagtac cagcctggct ccgggagcat gcccctgttc      780

cccagcatcc acctggagac gtgcgatgga gccgtgtctt ccctccagat cgtcacagag      840

ctgcagacta attacattgg gaagggttgt gaccgggaga cctactctga gaaatccctt      900

caaaagttat gtggagcctc ctctggcatc attgacctct tgccatcccc tagcgctgcc      960

accaactgga ctgcaggact gctggtggac agcagtgaga tgatcttcaa gtttgacggc     1020

aggcagggtg ccaaagtccc cgatgggatt gtgcccaaga acctgaccga tcagttcacc     1080

atcaccatgt ggatgaaaca cggccccagc cctggtgtga gagccgagaa ggaaaccatc     1140

ctctgcaact cagacaaaac cgaaatgaac cggcatcact atgccctgta tgtgcacaac     1200

tgccgcctcg tctttctctt gcggaaggac ttcgaccagg ctgacacctt tcgccccgcg     1260

gagttccact ggaagctgga tcagatttgt gacaaagagt ggcactacta tgtcatcaat     1320

gtggagtttc ctgtggtaac cttatacatg gatggagcaa catatgaacc atacctggtg     1380

accaacgact ggcccattca tccatctcac atagccatgc aactcacagt cggcgcttgt     1440

tggcaaggag gagaagtcac caaaccacag tttgctcagt tctttcatgg aagcctggcc     1500

agtctcacca tccgccctgg caaaatggaa agccagaagg tgatctcctg cctgcaggcc     1560

tgcaaggaag ggctggacat taattccttg gaaagccttg gccaaggaat aaagtatcac     1620

ttcaacccct cgcagtccat cctggtgatg gaaggtgacg acattgggaa cattaaccgt     1680

gctctccaga aagtctccta catcaactcc aggcagttcc caacggcggg tgtgcggcgc     1740

ctcaaagtat cctccaaagt ccagtgcttt ggggaagacg tatgcatcag tatccctgag     1800

gtagatgcct atgtgatggt cctccaggcc atcgagcccc ggatcaccct ccggggcaca     1860

gaccacttct ggagacctgc tgcccagttt gaaagtgcca ggggagtgac cctcttccct     1920

gatatcaaga ttgtgagcac cttcgccaaa accgaagccc ccggggacgt gaaaaccaca     1980

gaccccaaat cagaagtctt agaggaaatg cttcataact tagatttctg tgacattttg     2040

gtgatcggag gggacttgga cccaaggcag gagtgcttgg agctcaacca cagtgagctc     2100

caccaacgac acctggatgc cactaattct actgcaggct actccatcta cggtgtgggc     2160

tccatgagcc gctatgagca ggtgctacat cacatccgct accgcaactg gcgtccggct     2220

tctcttgagg cccggcgttt ccggattaag tgctcagaac tcaatgggcg ctacactagc     2280

aatgagttca acttggaggt cagcatcctt catgaagacc aagtctcaga taaggagcat     2340

gtcaatcatc tgattgtgca gcctcccttc ctccagtctg tccatcatcc tgagtcccgg     2400

agtagcatcc agcacagttc agtggtccca agc                                  2433


<210>  6021
<211>  1227
<212>  DNA
<213>  Homo Sapiens

<400>  6021
caccgcacca caggccccag gtttctaata agtgaccgtg acccacagtg caacctccac       60

tgctccagga ctcaacccaa acccatctgt gcctctgatg gcaggtccta cgagtccatg      120

tgtgagtacc agcgagccaa gtgccgagac ccgaccctgg gcgtggtgca tcgaggtaga      180

tgcaaagatg ctggccagag caagtgtcgc ctggagcggg ctcaagccct ggagcaagcc      240

aagaagcctc aggaagctgt gtttgtccca gagtgtggcg aggatggctc ctttacccag      300

gtgcagtgcc atacttacac tgggtactgc tggtgtgtca ccccggatgg gaagcccatc      360

agtggctctt ctgtgcagaa taaaactcct gtatgttcag gttcagtcac cgacaagccc      420

ttgagccagg gtaactcagg aaggaaagat gacgggtcta agccgacacc cacgatggag      480

acccagccgg tgttcgatgg agatgaaatc acagccccaa ctctatggat taaacacttg      540

gtgatcaagg actccaaact gaacaacacc aacataagaa attcagagaa agtctattcg      600

tgtgaccagg agaggcagag tgccctggaa gaggcccagc agaatccccg tgagggtatt      660

gtcatccctg aatgtgcccc tgggggactc tataagccag tgcaatgcca ccagtccact      720

ggctactgct ggtgtgtgct ggtggacaca gggcgcccgc tgcctgggac ctccacacgc      780

tacgtgatgc ccagttgtga gagcgacgcc agggccaaga ctacagaggc ggatgacccc      840

ttcaaggaca gggagctacc aggctgtcca gaagggaaga aaatggagtt tatcaccagc      900

ctactggatg ctctcaccac tgacatggtt caggccatta actcagcagc gcccactgga      960

ggtgggaggt tctcagagcc agaccccagc cacaccctgg aggagcgggt agtgcactgg     1020

tatttcagcc agctggacag caatagcagc aacgacatta acaagcggga gatgaagccc     1080

ttcaagcgct acgtgaagaa gaaagccaag cccaagaaat gtgcccggcg tttcaccgac     1140

tactgtgacc tgaacaaaga caaggtcatt tcactgcctg agctgaaggg ctgcctgggt     1200

gttagcaaag aagtaggacg cctcgtc                                         1227


<210>  6022
<211>  357
<212>  DNA
<213>  Homo Sapiens

<400>  6022
tggcatttcc acgagcaaag ggactgtgat gaacacaatg tcatggctcg ttacctccct       60

gccacagtgg agtttgctgt ccacacattc aaccaacaga gcaaggacta ctatgcctac      120

agactggggc acatcttgaa ttcctggaag gagcaggtgg agtccaagac tgtattctca      180

atggagctac tgctggggag aactaggtgt gggaaatttg aagacgacat tgacaactgc      240

catttccaag aaagcacaga gctgaacaat actttcacct gcttcttcac catcagcacc      300

aggccctgga tgactcagtt cagcctcctg aacaagacct gcttggaggg attccac         357


<210>  6023
<211>  1914
<212>  DNA
<213>  Homo Sapiens

<400>  6023
tttgagattg ctctgccacg agaaagcaac attacagttc tcataaagct ggggaccccg       60

actctgctgg caaaaccctg ttacatcgtc atttctaaaa gacatataac catgttgtcc      120

atcaagtctg gagaaagaat agtctttacc tttagctgcc agagtcctga gaatcacttt      180

gtcatagaga tccagaaaaa tattgactgt atgtcaggcc catgtccttt tggggaggtt      240

cagcttcagc cctcgacatc gttgttgcct accctcaaca gaactttcat ctgggatgtc      300

aaagctcata agagcatcgg tttagagctg cagttttcca tccctcgcct gaggcagatc      360

ggtccgggtg agagctgccc agacggagtc actcactcca tcagcggccg aatcgatgcc      420

accgtggtca ggatcggaac cttctgcagc aatggcactg tgtcccggat caagatgcaa      480

gaaggagtga aaatggcctt acacctccca tggttccacc ccagaaatgt ctccggcttc      540

agcattgcaa accgctcatc tataaaacgt ctgtgcatca tcgagtctgt gtttgagggt      600

gaaggctcag caaccctgat gtctgccaac tacccagaag gcttccctga ggatgagctc      660

atgacgtggc agtttgtcgt tcctgcacac ctgcgggcca gcgtctcctt cctcaacttc      720

aacctctcca actgtgagag gaaggaggag cgggttgaat actacatccc gggctccacc      780

accaaccccg aggtgttcaa gctggaggac aagcagcctg ggaacatggc ggggaacttc      840

aacctctctc tgcaaggctg tgaccaagat gcccaaagtc cagggatcct ccggctgcag      900

ttccaagttt tggtccaaca tccacaaaat gaaagcaata aaatctacgt ggttgacttg      960

agtaatgagc gagccatgtc actcaccatc gagccacggc ccgtcaaaca gagccgcaag     1020

tttgtccctg gctgtttcgt gtgtctagaa tctcggacct gcagtagcaa cctcaccctg     1080

acatctggct ccaaacacaa aatctccttc ctttgtgatg atctgacacg tctgtggatg     1140

aatgtggaaa aaaccataag ctgcacagac caccggtact gccaaaggaa atcctactca     1200

ctccaggtgc ccagtgacat cctccacctg cctgtggagc tgcatgactt ctcctggaag     1260

ctgctggtgc ccaaggacag gctcagcctg gtgctggtgc cagcccagaa gctgcagcag     1320

catacacacg agaagccctg caacaccagc ttcagctacc tcgtggccag tgccataccc     1380

agccaggacc tgtacttcgg ctccttctgc ccgggaggct ctatcaagca gatccaggtg     1440

aagcagaaca tctcggtgac ccttcgcacc tttgccccca gcttccaaca agaggcctcc     1500

aggcagggtc tgacggtgtc ctttatacct tatttcaaag aggaaggcgt tttcacggtg     1560

acccctgaca caaaaagcaa ggtctacctg aggaccccca actgggaccg gggcctgcca     1620

tccctcacct ctgtgtcctg gaacatcagc gtgcccagag accaggtggc ctgcctgact     1680

ttctttaagg agcggagcgg cgtggtctgc cagacagggc gcgcattcat gatcatccag     1740

gagcagcgga cccgggctga ggagatcttc agcctggacg aggatgtgct ccccaagcca     1800

agcttccacc atcacagctt ctgggtcaac atctctaact gcagccccac gagcggcaag     1860

cagctagacc tgctcttctc ggtgacactt accccaagga ctgtggactt gact           1914


<210>  6024
<211>  954
<212>  DNA
<213>  Homo Sapiens

<400>  6024
gcgctcacgc acgtgctgtg ccggccccgg cgcggctgct gcgggcgccg tcggagcgcg       60

tcccccgcct gcctgagcga cccctcgctg ggtgagcacg gtttcctgaa cctcaagagc      120

tcgggcctgc gtctgcacta tgtctcggct ggacgaggta acggacccct catgctgttt      180

ctgcacggct tccctgagaa ctggttctcc tggcgttacc agctccggga gttccagagc      240

cgcttccatg ttgtggctgt ggacttgcga ggctatggcc cctcggatgc acctcgggat      300

gtggactgct acacaatcga cctgctgctg gtggacatca aagatgtcat cctaggcctg      360

ggttactcga agtgcatcct tgtggcccat gactggggtg ccctccttgc ctggcatttc      420

tccatctact acccatccct ggtcgagcgg atggttgtgg tcagtggtgc ccccatgtcg      480

gtgtaccaag actattccct gcaccacatc agccagttct tccgttccca ctacatgttc      540

ctgttccagc tgccctggct gcccgagaag ctgctgtcta tgtctgactt tcagattctg      600

aagaccaccc tcacccaccg caagacaggc atcccatgct tgacccccag cgagctcgag      660

gccttccttt ataacttctc acagcctggt ggcctcactg ggcccctcaa ctactaccga      720

aacctcttca ggaacttccc cctggaaccc caggagctga ccacacccac attgctgctg      780

tggggggaga aggacactta cttggagctg gggctggtgg aagccatcgg cagccgcttt      840

gtgccgggcc gcttggaggc ccacatcctg ccaggcatag ggcattggat cccacagagc      900

aacccccagg agatgcacca gtacatgtgg gccttcttgc aagacctgct ggac            954


<210>  6025
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  6025
accttgagga cctccctgga cccaagcctg gagatctaca agaagatgtt tgaggtgaag       60

cggcgggagc agctgttggc actgaagaac ctggcacagc tgaacgacat ccaccagcag      120

tacaagatcc ttgatgtcat gctcaagggg ctctttaagg tgctggagga ctcccggaca      180

gtgctcaccg ctgctgatgt gctcccagat gggcccttcc cccaggacga gaagctgaag      240

gatgctttct cccacgtggt ggagaacacg gccttcttcg gcgatgtggt gctgcgcttc      300

ccgaggattg tgcactatta ctttgaccac aactccaact ggaacctcct catccgctgg      360

ggtatcagtt tctgcaacca gacaggcgtc ttcaaccagg ggccccactc gcccatcctc      420

agcctgatgg cccaggagct ggggatcagt gagaaagact ccaacttcca gaacccattt      480

aaaatcgacc gcacagagtt cattcccagc actgaccctt tccagaaggc cctgagagaa      540

gaagagaaac gccgaaagaa agaggagaag cggaaggaga tccgaaaagg cccaaggatc      600

tccagatccc agtctgagtt a                                                621


<210>  6026
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  6026
accttcaagc aggaggagag ggcagtgaga gataggaatc tcctccaggt tcatgaccat       60

aatcagccca tcccgtggaa agtgcagttt aacttgggca atagcagtcg tccgagcaat      120

cagtgccgca actccattca agggaagcac ctcatcacgg atgaactcgg ctacgtttgc      180

gagaggaagg atttgctggt aaatggctgc tgtaatgtca acgtccctag cacgaagcag      240

tactgctgtg atggctgctg gcccaacggc tgctgcagcg cctatgagta ctgtgtctcc      300

tgctgcctgc agcccaacaa gcaacttctc ctggagcgct tcctcaaccg ggcagccgtg      360

gcattccaga acctcttcat ggcagtcgaa gatcactttg agttgtgcct ggccaaatgc      420

aggacctcat ctcagagcgt gcagcatgag aacacctacc gggaccccat agcaaagtat      480

tgctatggag aaagcccgcc cgagctcttc cccgct                                516


<210>  6027
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  6027
cggaagaacc ggccggcggg cgccatccac tcgccttaca aggacggcag cagcaacaac       60

tcggagagat ggcagcacca gatcaaggag gtactggcct ccagccagga ggccctggtg      120

gtcaccgagc gcaagtacct caagagtgac tggtgcaaga cgcagccgct gcggcagacg      180

gtgagcgagg agggctgccg gagccgcacc atcctcaacc gcttctgcta cggccagtgc      240

aactccttct acatcccgcg gcacgtgaag aaggaggagg agtccttcca gtcctgcgcc      300

ttctgcaagc cccagcgcgt cacctccgtc ctcgtggagc tcgagtgccc cggcctggac      360

ccacccttcc gactcaagaa aatccagaag gtgaagcagt gccggtgcat gtccgtgaac      420

ctgagcgact cggacaagca g                                                441


<210>  6028
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  6028
ctttcacctc ccaccatgaa cctgaggcct cccaagtcat gtggaaatgt cttttattgg       60

gtgctggttc ttaactctgg acttctctac aagttttgtc aaactatcaa atgcagagca      120

aattggaggc ctgccagagc acccagaggg tggaatgaag caacagagag gcatcaggaa      180

aggagaacac agatggagac agagatggga ggcataagca ccacctactg gcacaggctg      240

tgcacttgca cggataggag agctgaaaag ttggtcatgg atggaaataa ctgctggttt      300

cacaaa                                                                 306


<210>  6029
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  6029
tggatatgca aaaaatggtt cccctacttc ttggtgaggt tcactgtgat atacaacgaa       60

cagatggcaa gcaagaagcg ggagctcttc agtaacctgc aggagtttgc gggcccctcc      120

gggaaactct ccctgctgga agtgggctgt ggcacggggg ccaacttcaa gttctaccca      180

cctgggtgca gggtgacctg tattgacccc aaccccaact ttgagaagtt tttgatcaag      240

agcattgcag agaaccgaca cctgcagttt gagcgctttg tggtagctgc cggggagaac      300

atgcaccagg tggctgatgg ctctgtggat gtggtggtct gcaccctggt gctgtgctct      360

gtgaagaacc aggagcggat tctccgcgag gtgtgcagag tgctgagacc gggaggggct      420

ttctatttca tggagcatgt ggcagctgag tgttcgactt ggaattactt ctggcaacaa      480

gtcctggatc ctgcctggca ccttctgttt gatgggtgca acctgaccag agagagctgg      540

aaggccctgg agcgggccag cttctctaag ctgaagctgc agcacatcca ggccccactg      600

tcctgggagt tggtgcgccc tcatatctat ggatatgctg tgaaa                      645


<210>  6030
<211>  1215
<212>  DNA
<213>  Homo Sapiens

<400>  6030
cagaattgcc tcaaaaagag tctagaagat gttgtcattg acatccagtc atctctttct       60

aagggaatca gaggcaatga gcccatatat acttcaactc aagaagactg cattaattct      120

tgctgttcaa caaaaaacat atcaggggac aaagcatgta acttgatgat cttcgacact      180

cgaaaaacag ctagacaacc caactgctac ctatttttct gtcccaacga ggaagcctgt      240

ccattgaaac cagcaaaagg acttatgagt tacaggataa ttacagattt tccatctttg      300

accagaaatt tgccaagcca agagttaccc caggaagatt ctctcttaca tggccaattt      360

tcacaagcag tcactcccct agcccatcat cacacagatt attcaaagcc caccgatatc      420

tcatggagag acacactttc tcagaagttt ggatcctcag atcacttgga gaaactattt      480

aagatggatg aagcaagtgc ccagctcctt gcttataagg aaaaaggcca ttctcagagt      540

tcacaatttt cctctgatca agaaatagct catctgctgc ctgaaaatgt gagtgcgctc      600

ccagctacgg tggcagttgc ttctccacat accacctcgg ctactccaaa gcccgccacc      660

cttctaccca ccaatgcttc agtgacacct tctgggactt cccagccaca gctggccacc      720

acagctccac ctgtaaccac tgtcacttct cagcctccca cgaccctcat ttctacagtt      780

tttacacggg ctgcggctac actccaagca atggctacaa cagcagttct gactaccacc      840

tttcaggcac ctacggactc gaaaggcagc ttagaaacca taccgtttac agaaatctcc      900

aacctaactt tgaacacagg gaatgtgtat aaccctactg cactttctat gtcaaatgtg      960

gagtcttcca ctatgaataa aactgcttcc tgggaaggta gggaggccag tccaggcagt     1020

tcctcccagg gcagtgttcc agaaaatcag tacggccttc catttgaaaa atggcttctt     1080

atcgggtccc tgctttttgg tgtcctgttc ctggtgatag gcctcgtcct cctgggtaga     1140

atcctctcgg aatcactccg caggaaacgt tactcaagac tggattattt gatcaatggg     1200

atctatgtgg acatc                                                      1215


<210>  6031
<211>  1218
<212>  DNA
<213>  Homo Sapiens

<400>  6031
ctgcttgctc cagttttccg gacactatct atcttgacta atcagtctaa ttgctggtta       60

tgtgaacatc tagataatgc agaacaaccc gaactagttt ttgttcctgc cagtgcaagc      120

acctggtgga cctattctgg acaatggatg tatgaaaggg tgtggtatcc acaagcagaa      180

gtacagaatc actctacttc ctcctatcgt aaagtgactt ggcactggga agcctccatg      240

gaagctcaag gtctatcctt tgctcaagta aggttattgg agggaaattt ttctctttgc      300

gtagaaaata aaaatggcag tggacccttc ctaggtaata tacctaaaca atactgtaat      360

caaatactat ggtttgattc tacagatggc accttcatgc cctctataga tgttacaaat      420

gaatccagga acgatgatga tgatacaagt gtttgcctag gcactagaca atgttcctgg      480

tttgcaggtt gcacaaaccg gacctggaac agctcagctg ttcccttgat tggtctgccc      540

aatacccaag actacaaatg ggtagatcga aattctggat tgacctggtc aggtaatgac      600

acctgtctct atagctgcca aaaccaaacc aaaggccttc tgtaccagct atttcgcaac      660

ctattttgct cttatggcct gacagaggca catgggaaat ggagatgtgc agatgccagc      720

ataactaatg acaaaggtca tgatggacac cggaccccca cctggtggct cacaggttcc      780

aatctgacct tgtctgtgaa caactctggc ctcttttttt tgtgcggcaa tggggtgtac      840

aaagggtttc cacctaaatg gtctgggcga tgtggacttg ggtatcttgt accttccctc      900

accagatacc tcaccttaaa tgctagccaa attacaaacc tgagatcctt cattcataaa      960

gtaacaccgc atagatgcac ccaaggagac acagacaatc cacctctgta ttgcaacccc     1020

aaggacaatt caacaataag ggcccttttt ccaagtttgg gaacttatga tttagaaaag     1080

gcaattctaa acatttccaa agcaatggaa caggaattca gtgccactaa gcagaccttg     1140

gaagcacacc aatcaaaagt tagcagttta gcctctgcat cccgaaagga tcatgtcttg     1200

gatataccga ccacccaa                                                   1218


<210>  6032
<211>  1500
<212>  DNA
<213>  Homo Sapiens

<400>  6032
attggttttc gctttgcttc atacatcaat aatgatatgg tgctgcagaa ggagcctgct       60

ggggcagtga tatggggctt cggtacacct ggagccacag tgaccgtgac cctgcgccaa      120

ggtcaggaaa ccatcatgaa gaaagtgacc agtgtaaaag ctcactctga tacgtggatg      180

gtggtactgg atcctatgaa gcctggagga cctttcgaag tgatggcaca acagactttg      240

gagaaaataa acttcaccct gagagttcat gacgtcctgt ttggagatgt ctggctctgt      300

agtgggcaga gtaacatgca gatgactgtg ttacagatat ttaatgctac aagggagttg      360

tctaacactg cggcatatca gtctgtccgc atcctctctg tctctcccat tcaagcagag      420

caggagctgg aggaccttgt tgcggttgac ttgcagtggt ctaagcccac ctcagaaaac      480

ttaggccatg gatatttcaa gtacatgtca gcagtgtgct ggctctttgg acgtcacctt      540

tatgacactc tgcagtatcc catcgggctg atcgcctcca gctggggcgg gacacccatt      600

gaagcctggt catctggacg gtcactgaaa gcctgtgggg tccctaaaca agggtccatt      660

ccatacgatt ctgtaactgg tcccagtaag cactctgttc tctggaatgc catgatccat      720

ccactgtgca atatgactct gaaaggggta gtatggtacc agggggagtc caatataaat      780

tataacacgg atctgtacaa ttgcacattc cctgcactca tcgaagactg gcgtgaaacc      840

ttccaccgtg gttcccaggg gcagacggag cgtttcttcc catttggact tgtccagtta      900

tcttcagatt tgtctaagaa gagctcagac gatggatttc cccagatccg ttggcatcaa      960

acagcagact tcggctatgt ccccaaccca aagatgccca atactttcat ggctgtagct     1020

atggatctct gtgatagaga ctcgcctttt ggcagcatcc accctcgaga taaacagact     1080

gtggcttatc ggctgcattt gggggcccgt gctctggctt atggtgagaa gaatttgacc     1140

tttgaaggac cactgcctga gaagatagaa ctcttggctc acaaggggct gctcaatctc     1200

acatattacc agcaaatcca ggtgcagaaa aaggacaaca agatatttga gatctcctgt     1260

tgcagtgacc atcgatgcaa gtggcttcca gcttctatga acaccgtctc cacccagtcc     1320

ctgaccctgg cgatcgattc ttgtcatggc actgtggttg ctctccgcta tgcttggacc     1380

acgtggcctt gtgaatataa gcagtgtccc ctataccacc ccagtagtgc cctgccagcc     1440

cctccattca ttgctttcat tacagaccag ggtcctggac atcagagcaa tgttgctaaa     1500


<210>  6033
<211>  1386
<212>  DNA
<213>  Homo Sapiens

<400>  6033
gggaagctgc tggtagtgcc catggatggg agccactggt tcaccatgca gtcggtggtg       60

gagaaactca tcctcagggg gcatgaggtg gtcgtagtca tgccagaggt gagttggcaa      120

ctgggaagat cactgaattg cacagtgaag acttactcaa cctcatacac tctggaggat      180

caggaccggg agttcatggt ttttgccgat gctcgctgga cggcaccatt gcgaagtgca      240

ttttctctat taacaagttc atccaatggt atttttgact tatttttttc aaattgcagg      300

agtttgttta atgaccgaaa attagtagaa tacttaaagg agagttgttt tgatgcagtg      360

tttctcgatc cttttgatgc ctgtggctta attgttgcca aatatttctc cctcccctct      420

gtggtcttcg ccaggggaat attttgccac tatcttgaag aaggtgcaca gtgccctgct      480

cctctttcct atgtccccag acttctctta gggttctcag acgccatgac tttcaaggag      540

agagtatgga accacatcat gcacttggag gaacatttat tttgccccta ttttttcaaa      600

aatgtcttag aaatagcctc tgaaattctc caaacccctg tcacggcata tgatctctac      660

agccacacat caatttggtt gttgcgaact gactttgttt tggagtatcc caaacccgtg      720

atgcccaata tgatcttcat tggtggtatc aactgtcatc agggaaagcc agtgcctatg      780

gaatttgaag cctacattaa tgcttctgga gaacatggaa ttgtggtttt ctctttggga      840

tcaatggtct cagaaattcc agagaagaaa gctatggcaa ttgctgatgc tttgggcaaa      900

atccctcaga cagtcctgtg gcggtacact ggaacccgac catcgaatct tgcgaacaac      960

acgatacttg ttaagtggct accccaaaac gatctgcttg gtcacccgat gacccgtgcc     1020

tttatcaccc atgctggttc ccatggtgtt tatgaaagca tatgcaatgg cgttcccatg     1080

gtgatgatgc ccttgtttgg tgatcagatg gacaatgcaa agcgcatgga gactaaggga     1140

gctggagtga ccctgaatgt tctggaaatg acttctgaag atttagaaaa tgctctaaaa     1200

gcagtcatca atgacaaaag ttacaaggag aacatcatgc gcctctccag ccttcacaag     1260

gaccgcccgg tggagccgct ggacctggcc gtgttctggg tggagtttgt gatgaggcac     1320

aagggcgcgc cacacctgcg ccccgcagcc cacgacctca cctggtacca gtaccattcc     1380

ttggac                                                                1386


<210>  6034
<211>  1386
<212>  DNA
<213>  Homo Sapiens

<400>  6034
gggaagctgc tggtagtgcc catggatggg agtcactggt tcaccatgca gtcggtggtg       60

gagaaactta tcctcagggg gcatgaggtg gttgtagtca tgccagaggt gagttggcaa      120

ctgggaaaat cactgaattg cacagtgaag acttactcaa cctcatacac tctggaggat      180

ctggaccggg aattcatgga tttcgccgat gctcaatgga aagcacaagt acgaagtttg      240

ttttctctat ttctgagttc atccaatggt ttttttaact tatttttttc gcattgcagg      300

agtttgttta atgaccgaaa attagtagaa tacttaaagg agagttcttt tgatgcggtg      360

tttcttgatc cttttgatgc ctgtggctta attgttgcca aatatttctc cctcccctct      420

gtggtcttcg ccaggggaat agcttgccac tatcttgaag aaggtgcaca gtgccctgct      480

cctctttcct atgtccccag aattctctta gggttctcag atgccatgac tttcaaggag      540

agagtacgga accacatcat gcacttggag gaacatttat tttgccagta tttttccaaa      600

aatgccctag aaatagcctc tgaaattctc caaacacctg tcacagcata tgatctctac      660

agccacacat caatttggtt gttgcgaaca gactttgttt tggactatcc caaacccgtg      720

atgcccaata tgatcttcat tggtggtatc aactgccatc agggaaagcc attgcctatg      780

gaatttgaag cctacattaa tgcttctgga gaacatggaa ttgtggtttt ctctttggga      840

tcaatggtct cagaaattcc agagaagaaa gctatggcaa ttgctgatgc tttgggcaaa      900

atccctcaga cagtcctgtg gcggtacact ggaacccgac catcgaatct tgcgaacaac      960

acgatacttg ttaagtggct accccaaaac gatctgcttg gtcacccgat gacccgtgcc     1020

tttatcaccc atgctggttc ccatggtgtt tatgaaagca tatgcaatgg cgttcccatg     1080

gtgatgatgc ccttgtttgg tgatcagatg gacaatgcaa agcgcatgga gactaaggga     1140

gctggagtga ccctgaatgt tctggaaatg acttctgaag atttagaaaa tgctctaaaa     1200

gcagtcatca atgacaaaag ttacaaggag aacatcatgc gcctctccag ccttcacaag     1260

gaccgcccgg tggagccgct ggacctggcc gtgttctggg tggagtttgt gatgaggcac     1320

aagggcgcgc cacacctgcg ccccgcagcc cacgacctca cctggtacca gtaccattcc     1380

ttggac                                                                1386


<210>  6035
<211>  1278
<212>  DNA
<213>  Homo Sapiens

<400>  6035
gctgtcattg actggcccac agaggagggc aaggaagtat gggattatgt gacggtccgc       60

aaggatgcct acatgttctg gtggctctat tatgccacca actcctgcaa gaacttctca      120

gaactgcccc tggtcatgtg gcttcagggc ggtccaggcg gttctagcac tggatttgga      180

aactttgagg aaattgggcc ccttgacagt gatctcaaac cacggaaaac cacctggctc      240

caggctgcca gtctcctatt tgtggataat cccgtgggca ctgggttcag ttatgtgaat      300

ggtagtggtg cctatgccaa ggacctggct atggtggctt cagacatgat ggttctcctg      360

aagaccttct tcagttgcca caaagaattc cagacagttc cattctacat tttctcagag      420

tcctatggag gaaaaatggc agctggcatt ggtctagagc tttataaggc cattcagcga      480

gggaccatca agtgcaactt tgcgggggtt gccttgggtg attcctggat ctcccctgtt      540

gattcggtgc tctcctgggg accttacctg tacagcatgt ctcttctcga agacaaaggt      600

ctggcagagg tgtctaaggt tgcagagcaa gtactgaatg ccgtaaataa ggggctctac      660

agagaggcca cagagctgtg ggggaaagca gaaatgatca ttgaacagaa cacagatggg      720

gtgaacttct ataacatctt aactaaaagc actcccacgt ctacaatgga gtcgagtcta      780

gaattcacac agagccacct agtttgtctt tgtcagcgcc acgtgagaca cctacaacga      840

gatgccttaa gccagctcat gaatggcccc atcagaaaga agctcaaaat tattcctgag      900

gatcaatcct ggggaggcca ggctaccaac gtctttgtga acatggagga ggacttcatg      960

aagccagtca ttagcattgt ggacgagttg ctggaggcag ggatcaacgt gacggtgtat     1020

aatggacagc tggatctcat cgtagatacc atgggtcagg aggcctgggt gcggaaactg     1080

aagtggccag aactgcctaa attcagtcag ctgaagtgga aggccctgta cagtgaccct     1140

aaatctttgg aaacatctgc ttttgtcaag tcctacaaga accttgcttt ctactggatt     1200

ctgaaagctg gtcatatggt tccttctgac caaggggaca tggctctgaa gatgatgaga     1260

ctggtgactc agcaagaa                                                   1278


<210>  6036
<211>  570
<212>  DNA
<213>  Homo Sapiens

<400>  6036
caaagtccaa tgactgtgct gtgctccata gactggttca tggtcacagt gcaccccttc       60

atgctaaaca acgatgtgtg tgtacacttt catgaactac acttgggcct gggttgcccc      120

ccaaaccatg ttcagccaca cgcctaccag ttcacctacc gtgttactga atgtggcatc      180

agggccaaag ctgtctctca ggacatggtt atctacagca ctgagataca ctactcttct      240

aagggcacgc catctaagtt tgtgatccca gtgtcatgtg ctgcccccca aaagtcccca      300

tggctcacca agccctgctc catgagagta gccagcaaga gcagggccac agcccagaag      360

gatgagaaat gctacgaggt gttcagcttg tcacagtcca gtcaaaggcc caactgcgat      420

tgtccacctt gtgtcttcag tgaagaagag catacccagg tcccttgtca ccaagcaggg      480

gctcaggagg ctcaacctct gcagccatct cactttcttg atatttctga ggattggtct      540

cttcacacag atgatatgat tgggtccatg                                       570


<210>  6037
<211>  156
<212>  DNA
<213>  Homo Sapiens

<400>  6037
atggggttta tattttcaaa atctatgaat gaaagcatga aaaatcaaaa ggagttcatg       60

cttatgaatg ctcgacttca gctggaaagg cagctcatca tgcagagtga aatgagggaa      120

agacaaatgg ccatgcagat tgcgtggtct cgggaa                                156


<210>  6038
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  6038
accaacgtca ccgctgccgt ccaggatgcc ggcctggccc acgaaggcga gggcgaggag       60

gagaccgaaa acaacgacag cgagaccgcg gagaactacg ctccgcctga aaccgaggat      120

gtttcaaata ggaatgtcgt caaagaagta gaattcggaa tgtgcaccgt tacatgtggt      180

attggtgtta gagaagttat attaacaaat ggatgccctg gtggtgaatc caagtgtgtt      240

gtacgggtag aagaatgccg tggaccaaca gattgtggct ggggtaaacc aatttcagaa      300

agtcttgaaa gtgttagatt ggcatgtatt cacacatctc ccttaaatcg tttcaaatat      360

atgtggaaac ttctaagaca agaccaacaa tccattatac ttgtaaatga ttcagcaatc      420

ctagaagtac gcaaggaaag tcaccccttg gctttcgagt gtgacacact ggataataat      480

gaaatagtag caactattaa attcacagtc tatacgagca gtgaattgca gatgagaaga      540

tcaagcctac cagccactga tgcagcccta attttt                                576


<210>  6039
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  6039
gccgtgatca ccggggcttg tgacaaggac tcccaatgtg gtggaggcat gtgctgtgct       60

gtcagtatct gggtcaagag cataaggatt tgcacaccta tgggcaaact gggagacagc      120

tgccatccac tgactcgtaa aaacaatttt ggaaatggaa ggcaggaaag aagaaagagg      180

aagagaagca aaaggaaaaa ggaggttcca ttttttgggc ggaggatgca tcacacttgc      240

ccatgtctgc caggcttggc ctgtttacgg acttcattta accgatttat ttgtttagcc      300

caaaag                                                                 306


<210>  6040
<211>  567
<212>  DNA
<213>  Homo Sapiens

<400>  6040
aagaatatct ggaaacgggc attgcctgcg aggctggccg agaaatcccg tgccgaggag       60

gcgggcgcgc ccggcggccc ccggcagccc cgagcagacc gctgcccgcc gcctccgcgg      120

acgctgcccc ccggcgcctg ccaggccgcg cgctgtcagg cggactccga gtgcccgcgg      180

caccggcgct gctgctacaa cggatgcgcc tacgcctgcc tagaagctgt gccgcccccg      240

ccagtcttag actggctggt gcagccgaaa cctcgatggc ttggtggcaa tggctggctc      300

ctggatggcc ctgaggaggt gttacaagca gaggcgtgca gcaccacgga ggatggggcc      360

gaacccctgc tctgtccctc gggctatgag tgccacatcc tgagcccagg tgacgtggcc      420

gaaggtatcc ccaaccgtgg gcagtgcgtc aagcagcgcc ggcaagcaga tgggcgaatc      480

ctacgacaca aactttacaa agaatatcca gaaggtgact caaagaatgt ggcagaacct      540

ggaaggggac aacagaagca ctttcag                                          567


<210>  6041
<211>  189
<212>  DNA
<213>  Homo Sapiens

<400>  6041
gagcagaagg agcttgacct catggacctc gtaggggaag acagaaagtg gatgatggcg       60

aggaagctga tgcaggtgaa cgacactctg acttccgaag atgccggact ccggaacagc      120

aagaactgca ccgaaccagc cctgcatgaa ttccccaatg acatcttcac aaacgaggat      180

agaagacaa                                                              189


<210>  6042
<211>  2337
<212>  DNA
<213>  Homo Sapiens

<400>  6042
ttctccgacg agaccctgga caaagtgccc aagtcagagg gctactgcag ccgtatcctg       60

cgcgcccagg gcacgcggcg cgagggctac accgagttca gcctccgcgt ggagggcgac      120

cccgacttct acaagccggg aaccagctac cgcgtaacac tttcagctgc tcctccctcc      180

tacttcagag gattcacatt aattgccctc agagagaaca gagagggtga taaggaagaa      240

gaccatgctg ggaccttcca gatcatagac gaagaagaaa ctcagtttat gagcaattgc      300

cctgttgcag tcactgaaag cactccacgg aggaggaccc ggatccaggt gttttggata      360

gcaccaccag cgggaacagg ctgcgtgatt ctgaaggcca gcatcgtaca aaaacgcatt      420

atttattttc aagatgaggg ctctctgacc aagaaacttt gtgaacaaga ttccacattt      480

gatggggtga ctgacaaacc catcttagac tgctgtgcct gcggaactgc caagtacaga      540

ctcacatttt atgggaattg gtccgagaag acacacccaa aggattaccc tcgtcgggcc      600

aaccactggt ctgcgatcat cggaggatcc cactccaaga attatgtact gtgggaatat      660

ggaggatatg ccagcgaagg cgtcaaacaa gttgcagaat tgggctcacc cgtgaaaatg      720

gaggaagaaa ttcgacaaca gagtgatgag gtcctcaccg tcatcaaagc caaagcccag      780

tggccagcct ggcagcctct caacgtgaga gcagcacctt cagctgaatt ttccgtggac      840

agaacgcgcc atttaatgtc cttcctgacc atgatgggcc ctagtcccga ctggaacgta      900

ggcttatctg cagaagatct gtgcaccaag gaatgtggct gggtccagaa ggtggtgcaa      960

gacctgattc cctgggacgc tggcaccgac agcggggtga cctatgagtc acccaacaaa     1020

cccaccattc cccaggagaa aatccggccc ctgaccagcc tggaccatcc tcagagtcct     1080

ttctatgacc cagagggtgg gtccatcact caagtagcca gagttgtcat cgagagaatc     1140

gcacggaagg gtgaacaatg caatattgta cctgacaatg tcgatgatat tgtagctgac     1200

ctggctccag aagagaaaga tgaagatgac acccctgaaa cctgcatcta ctccaactgg     1260

tccccatggt ccgcctgcag ctcctccacc tgtgacaaag gcaagaggat gcgacagcgc     1320

atgctgaaag cacagctgga cctcagcgtc ccctgccctg acacccagga cttccagccc     1380

tgcatgggcc ctggctgcag tgacgaagac ggctccacct gcaccatgtc cgagtggatc     1440

acctggtcgc cctgcagcat ctcctgcggc atgggcatga ggtcccggga gaggtatgtg     1500

aagcagttcc cggaggacgg ctccgtgtgc acgctgccca ctgaggaaac ggagaagtgc     1560

acggtcaacg aggagtgctc tcccagcagc tgcctgatga ccgagtgggg cgagtgggac     1620

gagtgcagcg ccacctgcgg catgggcatg aagaagcggc accgcatgat caagatgaac     1680

cccgcagatg gctccatgtg caaagccgag acatcacagg cagagaagtg catgatgcca     1740

gagtgccaca ccatcccatg cttgctgtcc ccatggtccg agtggagtga ctgcagcgtg     1800

acctgcggga agggcatgcg aacccgacag cggatgctca agtctctggc agaacttgga     1860

gactgcaatg aggatctgga gcaggtggag aagtgcatgc tccctgaatg ccccattgac     1920

tgtgagctca ccgagtggtc ccagtggtcg gaatgtaaca agtcatgtgg gaaaggccac     1980

gtgattcgaa cccggatgat ccaaatggag cctcagtttg gaggtgcacc ctgcccagag     2040

actgtgcagc gaaaaaagtg ccgcatccga aaatgccttc gaaatccatc catccaaaag     2100

ctacgctgga gggaggcccg agagagccgg cggagtgagc agctgaagga agagtctgaa     2160

ggggagcagt tcccaggttg taggatgcgc ccatggacgg cctggtcaga atgcaccaaa     2220

ctgtgcggag gtggaattca ggaacgttac atgactgtaa agaagagatt caaaagctcc     2280

cagtttacca gctgcaaaga caagaaggag atcagagcat gcaatgttca tccttgt        2337


<210>  6043
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  6043
tcctcaccct gcatcatgga acccagagac ttaccaccca agcctgggct ggtgggacac       60

cgaggggccc ccatgctggc tcccgagaac accctgatgt ccttgcggaa gacagctgaa      120

tgcggagcta ctgtgtttga gactgatgtg atggtcagct ccgatggggt ccccttcctc      180

atgcatgatg agcacctcag caggaccacg aatgtagcct ctgtattccc aacccgaatc      240

acagcccaca gcagtgactt ctcctggact gaactgaaga gactcaatgc tggatcctgg      300

ttcctagaga ggcgaccctt ctggggggcc aaaccgctgg caggccctga tcagaaagag      360

gctgagagtc agacggtacc agcattagaa gagctattgg aggaagctgc agccctcaac      420

ctttccatca tgttcgactt gcgccgaccc ccacagaacc acacatacta tgacactttt      480

gtgatccaga cattggagac tgtgctgaat gcaagggtgc cccaagccat ggtcttttgg      540

ctaccagatg aagatcgggc taatgtccaa cgacgggcac ctggaatgcg ccagatatat      600

ggacgtcagg gaggcaacag aacggagagg ccccagtttc ttaacctccc ctatcaagat      660

ctgccactat tggatatcaa ggcattgcat aaggataatg tctcggtgaa cctatttgta      720

gtgaacaagc cctggctctt ctctctgctt tggtgtgcag gggtggattc ggtcaccacc      780

aacgactgcc agctgctgca gcagatgcgt taccctatct ggcttattac ccctcaaacc      840

tac                                                                    843


<210>  6044
<211>  579
<212>  DNA
<213>  Homo Sapiens

<400>  6044
gccaagaccg gtgcggagct cgtgacctgc gggtcggtgc tgaagctgct caatacgcac       60

caccgcgtgc ggctgcactc gcacgacatc aaatacggat ccggcagcgg ccagcaatcg      120

gtgaccggcg tagaggcgtc ggacgacgcc aatagctact ggcggatccg cggcggctcg      180

gagggcgggt gcccgcgcgg gtccccggtg cgctgcgggc aggcggtgag gctcacgcat      240

gtgcttacgg gcaagaacct gcacacgcac cacttcccgt cgccgctgtc caacaaccag      300

gaggtgagtg cctttgggga agacggcgag ggcgacgacc tggacctatg gacagtgcgc      360

tgctctggac agcactggga gcgtgaggct gctgtgcgct tccagcatgt gggcacctct      420

gtgttcctgt cagtcacggg tgagcagtat ggaagcccca tccgtgggca gcatgaggtc      480

cacggcatgc ccagtgccaa cacgcacaat acgtggaagg ccatggaagg catcttcatc      540

aagcctagtg tggagccctc tgcaggtcac gatgaactc                             579


<210>  6045
<211>  153
<212>  DNA
<213>  Homo Sapiens

<400>  6045
acagcacgct tcatggcctt cctgaaggcc acggaggcac agctgtacgt ggaccagcac       60

gtgcaggacg acacgctgca caatgtctcg cttccgccgg aagtggcata cttcacctac      120

gccagggaca agtggtggcc ttcagaccct cag                                   153


<210>  6046
<211>  270
<212>  DNA
<213>  Homo Sapiens

<400>  6046
aagaccctgt gctccatgga agaagccatc aatgagagga tccaggaggt cgccggctcc       60

ctaatattta gggcaataag cagcattggc ctggagtgcc agagcgtcac ctccaggggg      120

gacctggcta cttgcccccg aggcttcgcc gtcaccggct gcacttgtgg ctccgcctgt      180

ggctcgtggg atgtgcgcgc cgagaccaca tgtcactgcc agtgcgcggg catggactgg      240

accggagcgc gctgctgtcg tgtgcagccc                                       270


<210>  6047
<211>  1065
<212>  DNA
<213>  Homo Sapiens

<400>  6047
gaatctccta tagatccaca gcctctcagc ttcaaagaac ccccgctctt gcttggtgtt       60

ctgcatccaa atacgaagct gcgacaggca gaaaggctgt ttgaaaatca acttgttgga      120

ccggagtcca tagcacatat tggggatgtg atgtttactg ggacagcaga tggccgggtc      180

gtaaaacttg aaaatggtga aatagagacc attgcccggt ttggttcggg cccttgcaaa      240

acccgagatg atgagcctgt gtgtgggaga cccctgggta tccgtgcagg gcccaatggg      300

actctctttg tggccgatgc atacaaggga ctatttgaag taaatccctg gaaacgtgaa      360

gtgaaactgc tgctgtcctc cgagacaccc attgagggga agaacatgtc ctttgtgaat      420

gatcttacag tcactcagga tgggaggaag atttatttca ccgattctag cagcaaatgg      480

caaagacgag actacctgct tctggtgatg gagggcacag atgacgggcg cctgctggag      540

tatgatactg tgaccaggga agtaaaagtt ttattggacc agctgcggtt cccgaatgga      600

gtccagctgt ctcctgcaga agactttgtc ctggtggcag aaacaaccat ggccaggata      660

cgaagagtct acgtttctgg cctgatgaag ggcggggctg atctgtttgt ggagaacatg      720

cctggatttc cagacaacat ccggcccagc agctctgggg ggtactgggt gggcatgtcg      780

accatccgcc ctaaccctgg gttttccatg ctggatttct tatctgagag accctggatt      840

aaaaggatga tttttaagct ctttagtcaa gagacggtga tgaagtttgt gccgcggtac      900

agcctcgtcc tagaactcag cgacagcggt gccttccgga gaagcctgca tgatcccgat      960

gggctggtgg ccacctacat cagcgaggtg cacgaacacg atgggcacct gtacctgggc     1020

tctttcaggt cccccttcct ctgcagactc agcctccagg ctgtt                     1065


<210>  6048
<211>  1170
<212>  DNA
<213>  Homo Sapiens

<400>  6048
atgaacggga cgcggaactg gtgtaccctg gtggacgtgc acccagagga ccaggcggcg       60

ggcagcgtgg acattctcag gctgactctc cagggtgaac tgacaggaga tgaacttgaa      120

cacatagccc agaaggcggg caggaagacc tatgccatgg tgtccagcca ctcagctggt      180

cattctctgg cttcagaact ggtggagtcc catgatggac atgaggagat cattaaggtg      240

tacttgaagg ggaggtctgg agacaagatg attcacgaga agaatattaa ccagctgaag      300

agtgaggtcc agtacatcca ggaggccagg aactgcctac agaagctccg ggaggatata      360

agtagcaagc ttgacaggaa cctaggagat tctctccatc gacaggagat acaggtggtg      420

ctagaaaagc caaatggctt tagtcagagt cccacagccc tgtacagcag cccacctgag      480

gtggacacct gtataaatga ggatgttgag agcttgagga agacggtgca ggacttgctg      540

gccaagcttc aggaggccaa gcggcaacac cagtcagact gtgtggcttt tgaggtcaca      600

ctcagccggt accagaggga agcagaacaa agtaatgtgg cccttcagag agaggaggac      660

agagtggagc agaaagaggc agaagtcgga gagctgcaga ggcgcttgct agggatggag      720

acggagcatc aggccttact ggcgaaagtg agggaagggg aggtggccct agaggaactt      780

cggagcaaca atgctgactg ccaagcagaa cgagaaaagg ctgctaccct ggaaaaggaa      840

gtggccgggt tgcgggagaa gatccaccac ttggatgaca tgctcaagag ccagcagcgg      900

aaagtccggc aaatgataga gcagctccag aattcaaaag ctgtgatcca gtcaaaggac      960

gccaccatcc aggagctcaa ggagaaaatc gcctatctgg aggcagagaa tttagagatg     1020

catgaccgga tggaacacct gatagaaaaa caaatcagtc atggcaactt cagcacccag     1080

gcccgggcca agacagagaa cccgggcagt attaggatat ccaagccgcc tagcccgaag     1140

cccatgcctg tcatccgagt ggtggaaacc                                      1170


<210>  6049
<211>  711
<212>  DNA
<213>  Homo Sapiens

<400>  6049
cagtttggag gcctgcccgt gcccctggac cagaccctgc ccttgaatgt gaatccagcc       60

ctgcccttga gtcccacagg tcttgcagga agcttgacaa atgccctcag caatggcctg      120

ctgtctgggg gcctgttggg cattctggaa aaccttccgc tcctggacat cctgaagcct      180

ggaggaggta cttctggtgg cctccttggg ggactgcttg gaaaagtgac gtcagtgatt      240

cctggcctga acaacatcat tgacataaag gtcactgacc cccagctgct ggaacttggc      300

cttgtgcaga gccctgatgg ccaccgtctc tatgtcacca tccctctcgg cataaagctc      360

caagtgaata cgcccctggt cggtgcaagt ctgttgaggc tggctgtgaa gctggacatc      420

actgcagaaa tcttagctgt gagagataag caggagagga tccacctggt ccttggtgac      480

tgcacccatt cccctggaag cctgcaaatt tctctgcttg atggacttgg ccccctcccc      540

attcaaggtc ttctggacag cctcacaggg atcttgaata aagtcctgcc tgagttggtt      600

cagggcaacg tgtgccctct ggtcaatgag gttctcagag gcttggacat caccctggtg      660

catgacattg ttaacatgct gatccacgga ctacagtttg tcatcaaggt c               711


<210>  6050
<211>  1263
<212>  DNA
<213>  Homo Sapiens

<400>  6050
gtgccgttct ttcctcagca atctggaaca ccgggtatgg ctagtttgag ccttgagaca       60

atgagacagt tgggaagtct gcagagatta aacacacttt ctcagtattc tagatacggc      120

tttggaaaat catttaattc tttgtggatg cacggtctcc tcccaccaca ttcctctctt      180

ccatggatga ggccaagaga acatgaaact caacagtatg aatattcttt gcctgtgcat      240

cccccacctc tcccatcaca gccatccttg aagcctcaac agccaggact gaaacctttt      300

ctccagtctg ctgctgcaac caccaaccag gccacagcac tgaaagaagc acttcagcct      360

ccaattcacc tgggacatct gcccttgcag gaaggagaac tgcctctggt tcagcagcag      420

gtggcaccat cagataagcc accaaagcct gagctcccag gagtagattt tgctgatcca      480

caaggtccat cactcccagg aatggatttt cctgatccac aaggtccatc actcccagga      540

ttggattttg ctgatccaca aggttcaaca attttccaaa tagcccgttt gatttctcac      600

ggaccaatgc cacaaaataa acaatctcca ctttatccag gaatgttgta cgtgcctttt      660

ggagcaaatc aattgaatgc ccctgccaga cttggcatca tgagttcaga agaagtggca      720

ggcgggagag aagacccaat ggcctatgga gccatgtttc caggatttgg aggcatgagg      780

cccggctttg agggaatgcc ccacaaccca gctatgggcg gtgacttcac tctggaattt      840

gactccccag tggctgccac caaaggccct gagaacgaag aaggaggtgc acaaggctcc      900

cctatgccgg aggccaaccc agacaatcta gaaaacccag ctttccttac agagctagaa      960

cctgctcccc acgcagggct ccctgctctc cctaaggatg acattcccgg cctgccaagg     1020

agcccttcag ggaagatgaa gggactcccc agcgtcaccc cagcagctgc tgacccactg     1080

atgacccctg aattagctga tgtttatagg acctacgatg ctgacatgac cacatccgtg     1140

gatttccagg aagaagcaac catggatacc acgatggccc caaactctct gcaaacatcc     1200

atgccaggaa acaaagccca ggagcccgag atgatgcatg acgcatggca tttccaagag     1260

ccc                                                                   1263


<210>  6051
<211>  276
<212>  DNA
<213>  Homo Sapiens

<400>  6051
tatggcttca aggccacctt caattatgaa aactgcttga agaaggtgag tctgctgctg       60

accaacactt ttgaccttga agatggcttt ttgacagcca gcaacctgga gcaggtgaag      120

ggctacctcg catctgccta cccaagcaaa tacagcgaga tgttcccgca aatcaaaaac      180

tgcagcttgg aatcggagct agacacggcc gtccagggca ctggcctggc attcatcgtc      240

tatacagagg ccattaaaaa catggaggtg tcccag                                276


<210>  6052
<211>  408
<212>  DNA
<213>  Homo Sapiens

<400>  6052
tcggaggtgc ccggggctgc tgctgaggga tcgggaggga gtggggtcgg cataggagat       60

cgcttcaaga ttgaggggcg tgcagttgtt ccaggggtga agcctcagga ctggatctcg      120

gcggcccgag tgctggtaga cggagaagag cacgtcggtt tccttaagac agatgggagt      180

tttgtggttc atgatatacc ttctggatct tatgtagtgg aagttgtatc tccagcttac      240

agatttgatc ccgttcgagt ggatatcact tcgaaaggaa aaatgagagc aagatatgtg      300

aattacatca aaacatcaga ggttgtcaga ctgccctatc ctctccaaat gaaatcttca      360

ggtccacctt cttactttat taaaagggaa tcgtggggct ggacagac                   408


<210>  6053
<211>  378
<212>  DNA
<213>  Homo Sapiens

<400>  6053
aagcctttta tgctcagcat tcagagagaa gaatcgacct gcactgccat ccacacagat       60

atcatggacg actggctgga ctgtgccttc acctgtggtg tgcactgcca cggtcagggg      120

aagtacccgt gtcttcaggt gtttgtgaac ctcagccatc caggtcagaa agctctccta      180

cattataatg aagaggctgt ccagataaat cccaagtgct tttacacacc taagtgccac      240

caagatagaa atgatttgct caacagtgct ctggacataa aagaattctt cgatcacaaa      300

aatggaaccc ccttttcatg cttctacagt ccagccagcc aatctgaaga tgtcattctt      360

ataaaaaagt atgaccaa                                                    378


<210>  6054
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  6054
ttccctctaa tctgcgaaag caaatcagtt gccggcctaa ccttgaccta tgatggaaat       60

aattcagtgg catctcatgt agatgtacca ctttcttatt gcaactcaga gtgcaattgt      120

gatgaaagtc agtgggaacc agtctgtggg aacaatggaa taacttacct gtcaccttgt      180

ctagcaggat gcaaatcctc aagtggtatt aaaaagcata cagtgtttta taactgtagt      240

tgtgtggaag taactggtct ccagaacaga aattactcag cacacttggg tgaatgccca      300

agagataata cttgtacaag gaaatttttc atctat                                336


<210>  6055
<211>  645
<212>  DNA
<213>  Homo Sapiens

<400>  6055
ggagggctgc tgaagtatca aactaattta gatacccacc ctcccggctg catcagtctt       60

aaccgaacca gctctcagaa tatttcctta ccagagtatt tctcagaaca ttttcatgaa      120

cctttccctg aaggattttc aaaaccggca gagtttaccc agcacaaatt tgtgaagatt      180

tgtatggaag agcccagatt ccaagctaat tttccacaga cttggctttg gatttctgga      240

cctttgtgcc tgtactgtgc cgaaagactt tacaggtata tccggagcaa taagccagtc      300

accatcattt cggtcataag tcatccctca gatgtcatgg aaatccgaat ggtcaaagaa      360

aattttaaag caagacctgg tcagtatatt actctacatt gtcccagtgt atctgcatta      420

gaaaatcatc catttaccct cacaatgtgt ccaactgaaa ccaaagcaac atttggggtt      480

catcttaaaa tagtaggaga ctggacagaa cgatttcgag atttactact gcctccatct      540

agtcaagact ccgaaattct gcccttcatt caatctagaa attatcccaa gctgtatatt      600

gatggtcctt ttggaagtcc atttgaggaa tcactgaact atgag                      645


<210>  6056
<211>  465
<212>  DNA
<213>  Homo Sapiens

<400>  6056
ctgtccttca ccctggagga ggaggatatc acagggacct ggtacgtgaa ggccatggtg       60

gtcgataagg actttccgga ggacaggagg cccaggaagg tgtccccagt gaaggtgaca      120

gccctgggcg gtgggaagtt ggaagccacg ttcaccttca tgagggagga tcggtgcatc      180

cagaagaaaa tcctgatgcg gaagacggag gagcctggca aatacagcgc ctatgggggc      240

aggaagctca tgtacctgca ggagctgccc aggagggacc actacatctt ttactgcaaa      300

gaccagcacc atgggggcct gctccacatg ggaaagcttg tgggtaggaa ttctgatacc      360

aaccgggagg ccctggaaga atttaagaaa ttggtgcagc gcaagggact ctcggaggag      420

gacattttca cgcccctgca gacgggaagc tgcgttcccg aacac                      465


<210>  6057
<211>  495
<212>  DNA
<213>  Homo Sapiens

<400>  6057
tggagcaata attatgcggt ggactgccct caacactgtg acagcagtga gtgcaaaagc       60

agcccgcgct gcaagaggac agtgctcgac gactgtggct gctgccgagt gtgcgctgca      120

gggcggggag aaacttgcta ccgcacagtc tcaggcatgg atggcatgaa gtgtggcccg      180

gggctgaggt gtcagccttc taatggggag gatccttttg gtgaagagtt tggtatctgc      240

aaagactgtc cctacggcac cttcgggatg gattgcagag agacctgcaa ctgccagtca      300

ggcatctgtg acagggggac gggaaaatgc ctgaaattcc ccttcttcca atattcagta      360

accaagtctt ccaacagatt tgtttctctc acggagcatg acatggcatc tggagatggc      420

aatattgtga gagaagaagt tgtgaaagag aatgctgccg ggtctcccgt aatgaggaaa      480

tggttaaatc cacgc                                                       495


<210>  6058
<211>  213
<212>  DNA
<213>  Homo Sapiens

<400>  6058
gccaagaatt tcgaggatgt cagatgtaaa tgtatctgcc ctccctataa agaaaattct       60

gggcatattt ataataagaa catatctcag aaagattgtg attgccttca tgttgtggag      120

cccatgcctg tgcgggggcc tgatgtagaa gcatactgtc tacgctgtga atgcaaatat      180

gaagaaagaa gctctgtcac aatcaaggtt acc                                   213


<210>  6059
<211>  3126
<212>  DNA
<213>  Homo Sapiens

<400>  6059
aagaatgaag atcaggaaat gtgccatgaa tttcaggcat ttatgaaaaa tggaaaactg       60

ttctgtcccc aggataagaa attttttcaa agtcttgatg gaataatgtt catcaataaa      120

tgtgccacgt gcaaaatgat actggaaaaa gaagcaaaat cacagaagag ggccaggcat      180

ttagcaagag ctcccaaggc tactgcccca acagagctga attgtgatga ttttaaaaaa      240

ggagaaagag atggggattt tatctgtcct gattattatg aagctgtttg tggcacagat      300

gggaaaacat atgacaacag atgtgcactg tgtgctgaga atgcgaaaac cgggtcccaa      360

attggtgtaa aaagtgaagg ggaatgtaag agcagtaatc cagagcagga tgtatgcagt      420

gcttttcggc cctttgttag agatggaaga cttggatgca caagggaaaa tgatcctgtt      480

cttggtcctg atgggaagac gcatggcaat aagtgtgcaa tgtgtgctga gctgttttta      540

aaagaagctg aaaatgccaa gcgagagggt gaaactagaa ttcgacgaaa tgctgaaaag      600

gatttttgca aggaatatga aaaacaagtg agaaatggaa ggcttttttg tacacgggag      660

agtgatccag tccgtggccc tgacggcagg atgcatggca acaaatgtgc cctgtgtgct      720

gaaattttca agcagcgttt ttcagaggaa aacagtaaaa cagatcaaaa tttgggaaaa      780

gctgaagaaa aaactaaagt taaaagagaa attgtgaaac tctgcagtca atatcaaaat      840

caggcaaaga atggaatact tttctgtacc agagaaaatg accctattcg tggtccagat      900

gggaaaatgc atggcaactt gtgttccatg tgtcaagcct acttccaagc agaaaatgaa      960

gaaaagaaaa aggctgaagc acgagctaga aacaaaagag aatctggaaa agcaacctca     1020

tatgcagagc tttgcagtga atatcgaaag cttgtgagga acggaaaact tgcttgcacc     1080

agagagaacg atcctatcca gggcccagat gggaaagtgc atggcaacac ctgctccatg     1140

tgtgaggtct tcttccaagc agaagaagaa gaaaagaaaa agaaggaagg taaatcaaga     1200

aacaaaagac aatctaagag tacagcttcc tttgaggagt tgtgtagtga ataccgcaaa     1260

tccaggaaaa acggacggct tttttgcacc agagagaatg accccatcca gggcccagat     1320

ggaaaaatgc atggcaacac ctgctccatg tgtgaggcct tctttcaaca agaagaaaga     1380

gcaagagcaa aggctaaaag agaagctgca aaggaaatct gcagtgaatt tcgggaccaa     1440

gtgaggaatg gaacacttat atgcaccagg gagcataatc ctgtccgtgg cccagatggc     1500

aaaatgcatg gaaacaagtg tgccatgtgt gccagtgtgt tcaaacttga agaagaagag     1560

aagaaaaatg ataaagaaga aaaagggaaa gtcgaggctg aaaaagttaa gagagaagca     1620

gttcaggagc tgtgcagtga atatcgtcat tatgtgagga atggacgact cccctgtacc     1680

agagagaatg atcctattga gggtctagat gggaaaatcc acggcaacac ctgctccatg     1740

tgtgaagcct tcttccagca agaagcaaaa gaaaaagaaa gagctgaacc cagagcaaaa     1800

gtcaaaagag aagctgaaaa ggagacatgc gatgaatttc ggagactttt gcaaaatgga     1860

aaacttttct gcacaagaga aaatgatcct gtgcgtggcc cagatggcaa gacccatggc     1920

aacaagtgtg ccatgtgtaa ggcagtcttc cagaaagaaa atgaggaaag aaagaggaaa     1980

gaagaggaag atcagagaaa tgctgcagga catggttcca gtggtggtgg aggaggaaac     2040

actcaggacg aatgtgctga gtatcgggaa caaatgaaaa atggaagact cagctgtact     2100

cgggagagtg atcctgtacg tgatgctgat ggcaaatcgt acaacaatca gtgtaccatg     2160

tgtaaagcaa aattggaaag agaagcagag agaaaaaatg agtattctcg ctccagatca     2220

aatgggactg gatcagaatc agggaaggat acatgtgatg agtttagaag ccaaatgaaa     2280

aatggaaaac tcatctgcac tcgagaaagt gaccctgtcc ggggtccaga tggcaagaca     2340

catggcaata agtgtactat gtgtaaggaa aaactggaaa gggaagcagc tgaaaaaaaa     2400

aagaaagagg atgaagacag gagcaataca ggagaaagga gcaatacagg agaaaggagc     2460

aatgacaaag aggatctgtg tcgtgaattt cgaagcatgc agagaaatgg aaagcttatc     2520

tgcaccagag aaaataaccc tgttcgaggc ccatatggca agatgcacat caataaatgt     2580

gctatgtgtc agagcatctt tgatcgagaa gctaatgaaa gaaaaaagaa agatgaagag     2640

aaatcaagta gcaagccctc aaataatgca aaggatgagt gcagtgaatt tcgaaactat     2700

ataaggaaca atgaactcat ctgccctaga gagaatgacc cagtgcacgg tgctgatgga     2760

aagttctata caaacaagtg ctacatgtgc agagctgtct ttctaacaga agctttggaa     2820

agggcaaagc ttcaagaaaa gccatcccat gttagagctt ctcaagagga agacagccca     2880

gactctttca gttctctgga ttctgagatg tgcaaagact accgagtatt gcccaggata     2940

ggttatcttt gtccaaagga tttaaagcct gtctgtggtg acgatggcca aacctacaac     3000

aatccttgca tgctctgtca tgaaaacctg atacgccaaa caaatacaca catccgcagt     3060

acagggaagt gtgaggagag cagcacccca ggaaccaccg cagccagcat gcccccgtct     3120

gacgaa                                                                3126


<210>  6060
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  6060
cagggctccg gtctcactac ctgcgtcaat gtcactgaga tatcagacag cgtaccaagc       60

cctgtaccca cgagggagac tgacatcgca cagggagttc ccagagcttt ggtgtccgcc      120

ctccccggaa tggaagcacc cttgtcccac ctggagagcc gctaccttcc cgcccacttc      180

tcaccc                                                                 186


<210>  6061
<211>  501
<212>  DNA
<213>  Homo Sapiens

<400>  6061
ttaaaaagta gcactttgaa gcctactatt gaagcattgc ctaatgtgct acctttaaat       60

gaagatgtta ataagcagga agaaaagaat gaagatcata ctcccaatta tgctcctgct      120

aatgagaaaa atggcaatta ttataaagat ataaaacaat atgtgttcac aacacaaaat      180

ccaaatggca ctgagtctga aatatctgtg agagccacaa ctgacctgaa ttttgctcta      240

aaaaacgata aaactgtcaa tgcaactaca tatgaaaaat ccaccattga agaagaaaca      300

actactagcg aaccctctca taaaaatatt caaagatcaa ccccaaacgt gcctgcattt      360

tggacaatgt tagctaaagc tataaatgga acagcagtgg tcatggatga taaagatcaa      420

ttatttcacc caattccaga gtctgatgtg aatgctacac agggagaaaa tcagccagat      480

ctagaggatc tgaagatcaa a                                                501


<210>  6062
<211>  1524
<212>  DNA
<213>  Homo Sapiens

<400>  6062
ccaacatttc aaccacagac tgagaaaact aagcaaagct gtgtggaaga gcagaggcag       60

gaagaaaaaa acaaagacaa tattggtttt caccatttgg gcaagagaat aaatcaagag      120

ctatcatcta aagaaaatat tgtccaggaa agaaagaaag atttgtccct ttctgaagcc      180

agtgagaata agggaagtag taaatctcaa aattatttca caaatagaca gagactgaat      240

aaagaatata gtatcagtaa caaagagaat actcacaatg gcctgaggat gtcaatttat      300

cctaagtcaa ctgggaataa agggtttgag gatggagatg atgctatcag caaactacat      360

gaccaagaag aatatggcgc agctctcatc agaaataaca tgcaacatat aatggggcca      420

gtgactgcaa ttaaactcct gggggaagaa aacaaagaga acacacctag gaatgttcta      480

aacataatcc cagcaagtat gaattatgct aaagcacact cgaaggataa aaagaagcct      540

caaagagatt cccaagccca gaaaagtcca gtaaaaagca aaagcaccca tcgtattcaa      600

cacaacattg actacctaaa acatctctca aaagtcaaaa aaatccccag tgattttgaa      660

ggcagcggtt atacagatct tcaagagaga ggggacaatg atatatctcc tttcagtggg      720

gacggccaac cttttaagga cattcctggt aaaggagaag ctactggtcc tgacctagaa      780

ggcaaagata ttcaaacagg gtttgcaggc ccaagtgaag ctgagagtac tcatcttgac      840

acaaaaaagc caggttataa tgagatccca gagagagaag aaaatggtgg aaataccatt      900

ggaactaggg atgaaactgc gaaagaggca gatgctgttg atgtcagcct tgtagagggc      960

agcaacgata tcatgggtag taccaatttt aaggagctcc ctggaagaga aggaaacaga     1020

gtggatgctg gcagccaaaa tgctcaccaa gggaaggttg agtttcatta ccctcctgca     1080

ccctcaaaag agaaaagaaa agaaggcagt agtgatgcag ctgaaagtac caactataat     1140

gaaattccta aaaatggcaa aggcagtacc agaaagggtg tagatcattc taataggaac     1200

caagcaacct taaatgaaaa acaaaggttt cctagtaagg gcaaaagtca gggcctgccc     1260

attccttctc gtggtcttga taatgaaatc aaaaacgaaa tggattcctt taatggcccc     1320

agtcatgaga atataataac acatggcaga aaatatcatt atgtacccca cagacaaaat     1380

aattctacac ggaataaggg tatgccacaa gggaaaggct cctggggtag acaaccccat     1440

tccaacagga ggtttagttc ccgtagaagg gatgacagta gtgagtcatc tgacagtggc     1500

agttcaagtg agagcgatgg tgac                                            1524


<210>  6063
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  6063
ttcaaaggga ggtttgtggg caggcctgga agctacgtct atgtattcga tggttaccgc       60

atggaagagt gtgctccagg gggctgtctc atggagctct gcattcagct cagcatcatc      120

atgttgggga agcagttgat ccagaacaac atctttgaga ttggagtccc gaagctaaag      180

aaactatttc gaaagctgaa agatgagacc gaagctggag aaactgactc tgcccattcg      240

aaacatccag agcagtggga cctagactac agcttggaac catacacagg actgactccg      300

gagtacatgg aa                                                          312


<210>  6064
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  6064
tcccttctta ggcgcctggg tgagcacatt cagcagtttc aggagagctc tgcccagggc       60

ctgggcctga gcctggggcc aggtgctgca gccctcccaa aagtggggtg gctggagcaa      120

ctgctggacc ccttcaacgt gtccgacaga cgatccttcc tacagcgtta ctgggtgaat      180

gaccaacatt gggttggcca ggatggaccc atattcctgc atctaggggg tgagggcagc      240

cttgggcctg gctcagtgat gagaggccat cccgcagcct tggccccagc ctggggcgcc      300

ctggtgataa gcctggaaca cagattttat ggcctgagta tacctgctgg aggcctggaa      360

atggcccagc tccgcttctt gtccagccgc cttgcgctgg ctgatgtggt ctctgcccgc      420

ctggcacttt cccgcctctt taacatctcc tcctccagcc cctggatctg cttcggaggc      480

tcctatgccg gctccttggc cgcctgggcc cggctgaagt tcccccatct cattttcgcg      540

tcggtcgcct cctccgcccc ggtgcgggcc gtgctggatt tctccgagta taatgacgtg      600

gtatcccgaa gcctaatgag caccgcgatc ggcgggtccc tggagtgccg ggcggcggtg      660

tccgtcgcct tcgctgaagt ggagcggcgg ctgcgctcgg gtggggcggc tcaagcagca      720

ttgcggacgg agctgagcgc ttgcgggccc ctgggccgcg ctgaaaacca ggcggagctg      780

ttgggggcgc tgcaggcact ggtgggaggt gtagtgcagt atgatgggca gacgggagcg      840

ccgctaagcg tgcgacagct ctgcggactt ctcctcgggg gcgggggcaa ccgcagccac      900

tccacgccct actgcgggct tcgtcgggcg gtgcagattg tcttgcacag cctgggccag      960

aagtgtttaa gcttttcccg agcagagaca gtggcacagc tgaggagcac agaacctcaa     1020

ctgtctggtg tgggtgaccg gcagtggttg tatcagacat gtaccgagtt cggcttctat     1080

gtcacctgtg agaatcccag atgtcctttc tcccagctcc cagcactgcc ctcccagcta     1140

gacctatgtg agcaggtgtt tgggctctca gccttgtcag tagcccaggc tgtggctcag     1200

acgaactcct actacggtgg ccagacccct ggggctaaca aagtgctgtt tgttaatggg     1260

gacacagacc cctggcatgt gctaagtgta acacaggctt taggatcctc agaatcaact     1320

cttcttatcc gcactggctc ccactgcttg gacatggcac ctgagaggcc ctcagactcc     1380

cccagcctcc gcctagggcg ccagaacatc ttccagcagc tacagacctg gctcaagctg     1440

gcaaaggaga gccagattaa gggtgaagtc                                      1470


<210>  6065
<211>  441
<212>  DNA
<213>  Homo Sapiens

<400>  6065
ggccacccgg atgtagccgc ctgtcccggg agcctggact gtgccctgaa gaggcgggca       60

aggtgtcctc ctggtgcaca tgcctgtggg ccctgccttc agcccttcca ggaggaccag      120

caagggctct gtgtgcccag gatgcgccgg cctccaggcg ggggccggcc ccagcccaga      180

ctggaagatg agattgactt cctggcccag gagcttgccc ggaaggagtc tggacactca      240

actccgcccc tacccaagga ccgacagcgg ctcccggagc ctgccaccct gggcttctcg      300

gcacgggggc aggggctgga gctgggcctc ccctccactc caggaacccc cacgcccacg      360

ccccacacct ccctgggctc ccctgtgtca tccgacccgg tgcacatgtc gcccctggag      420

ccccggggag ggcaaggcga c                                                441


<210>  6066
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  6066
gtgcatggaa tatttatgga ccgtctagct tccaagaagc tctgtgcaga tgatgagtgt       60

gtctatacta tttctctggc tagtgctcaa gaagattata atgccccgga ctgtagattc      120

attaacgtta aaaaagggca gcagatctat gtgtactcaa agctggtaaa agaaaatgga      180

gctggagaat tttgggctgg cagtgtttat ggtgatggcc aggacgagat gggagtcgtg      240

ggttatttcc ccaggaactt ggtcaaggaa cagcgtgtgt accaggaagc taccaaggaa      300

gttcccacca cggatattga cttcttctgc gag                                   333


<210>  6067
<211>  516
<212>  DNA
<213>  Homo Sapiens

<400>  6067
acctccatct cgccaggaag atgcaagtgg aataagcaca ctctaactta caggattatc       60

aattacccac atgatatgaa gccatccgca gtgaaagaca gtatatataa tgcagtttcc      120

atctggagca atgtgacccc tttgatattc cagcaagtgc agaatggaga tgcagacatc      180

aaggtttctt tctggcagtg ggcccatgaa gatggttggc cctttgatgg gccaggtggt      240

atcttaggcc atgccttttt accaaattct ggaaatcctg gagttgtcca ttttgacaag      300

aatgaacact ggtcagcttc agacactgga tataatctgt tcctggttgc aactcatgag      360

attgggcatt ctttgggcct gcagcactct gggaatcaga gctccataat gtaccccact      420

tactggtatc acgaccctag aaccttccag ctcagtgccg atgatatcca aaggatccag      480

catttgtatg gagaaaaatg ttcatctgac atacct                                516


<210>  6068
<211>  3309
<212>  DNA
<213>  Homo Sapiens

<400>  6068
atgccaatgc acatgccccg aatgcctgga tttagcagta aaagtgagga gatgatgcgg       60

tataatcaat tcaactttat gaacggccca catatggcac acctggggcc cttctttgga      120

aacggtctcc ctcagcaatt tccacagtac cagatgccca tgtggcctca gccaccaccc      180

aacacatggc atccacggaa atcctcagca cccaaacgtc ataacaagac tgatcagacc      240

caagaaaccc agaaacccaa ccagactcag tcaaaaaagc caccacaaaa gcggcctttg      300

aagcagccat cacataatca acctcagccc gaagaggaag ctcaaccccc tcaggcattc      360

ccaccatttg gaaatgggct attcccctat caacaaccac catggcaaat tccacagagg      420

ttaccaccac caggttatgg acgcccacca atcagcaatg aagaaggggg gaatccttac      480

tttggatatt ttggatatca tggctttggg ggtcgccctc cttattattc agaagaaatg      540

tttgaacaag attttgaaaa acccaaagaa gaagatcctc ctaaagcaga aagtccaggc      600

acagaaccca cagctaattc aacagtcact gagacgaatt ctacccaacc aaatcctaaa      660

gggagtcagg gaggaaatga caccagcccc acaggaaaca gtaccccagg actaaacact      720

gggaacaacc ctccagctca aaatgggatt ggcccactcc ctgcagtcaa cgcttcaggc      780

cagggagggc caggaagtca aatcccatgg agaccaagtc agccaaatat tcgtgaaaat      840

catccatatc ctaatataag aaattttcct tcaggaagac agtggtattt cactggtact      900

gtcatggggc acagacagaa taggcctttt tacagaaatc aacaagttca aaggggtcct      960

cggtggaact tctttgcttg ggaacgtaaa caagtagctc gtccaggaaa tccagtttat     1020

cacaaagctt accctcctac ttcaagaggc aattatccca attatgcagg aaatccagca     1080

aatctcagaa gaaagcctca ggggccaaat aaacaccctg taggaactac tgttgcccca     1140

ctgggtccca aacctggccc tgttgttcgc aatgaaaaaa tccaaaatcc aaaggagaag     1200

cccctgggtc caaaagaaca aataatagtt cctacaaaga atccaaccag cccctggaga     1260

aactctcaac agtatgaagt taataaatca aattataaac tgcctcactc tgagggttat     1320

atgccagtcc caaattttaa ttctgttgat caacatgaaa actcctatta cccaagagga     1380

gattccagaa aagtcccaaa ttctgatgga caaacccaaa gccagaattt gcccaaaggg     1440

attgttttag ggtcaagaag gatgccatat gaatcagaaa ctaatcagtc agaattaaag     1500

cacagctcat atcagcctgc tgtataccct gaggaaatcc cttctcctgc aaaagaacat     1560

tttcctgctg gaagaaatac ttgggaccac caagaaatct ctccaccttt taaggaagat     1620

ccagggaggc aagaagaaca tttaccccat ccttcccatg gttctagagg aagtgttttc     1680

taccctgaat ataacccata tgatcccagg gaaaactcac cataccttag aggcaataca     1740

tgggatgaga gagatgattc tcccaatact atggggcaaa aagaaagtcc actctacccc     1800

ataaataccc cagaccagaa ggagatagtc ccttataatg aagaggaccc agttgatcca     1860

actggagatg aagtctttcc tggacaaaat agatggggtg aagagttgag cttcaaagga     1920

ggcccaacag ttaggcacta tgaaggtgaa caatatacct caaatcagcc aaaggaatat     1980

cttccctatt ctttagataa tccatcaaaa ccaagggagg atttttatta cagtgaattt     2040

tacccatgga gcccggatga gaattttcca tcatataata cagcttctac tatgccacca     2100

cctatagaga gcaggggcta ctacgttaat aatgccgctg gaccagaaga aagcactcta     2160

tttccttcac ggaattcctg ggaccacagg atacaagccc aagggcagag agaaagaagg     2220

ccgtatttta acagaaatat ctgggatcag gcaacacatt tacaaaaagc cccagctagg     2280

ccaccagacc agaaaggtaa ccagccctat tacagtaaca ccccagctgg gcttcagaaa     2340

aatccaatat ggcatgaagg tgagaatttg aactatggca tgcaaataac taggatgaat     2400

tctccagaga gagaacattc atctttccct aacttcatcc caccaagtta cccatcaggt     2460

caaaaagaag cacatttatt tcacctaagc cagagaggct cttgctgtgc tggtagctcc     2520

acagggccca aggacaatcc actagctcta caagactaca ctccatccta tggtcttgca     2580

cctggggaga accaagacac cagtcctctg tatacagacg gtagtcatac caagcagaca     2640

agagatatca tctccccaac aagcatccta ccaggccaaa gaaacagctc agagaagagg     2700

gaaagccaaa acccttttag agatgatgtg tccacgctga ggaggaacac accatgttct     2760

ataaagaatc aactgggcca aaaggaaatt atgccctttc ctgaagccag ttcccttcaa     2820

tcaaagaata caccttgtct caaaaatgat cttggaggag atgggaacaa cattctggaa     2880

caagtttttg aagacaacca gctcaatgaa agaactgttg accttactcc tgagcagctt     2940

gttattggta cacctgatga aggctccaat ccagaaggca tccaaagtca agtccaagaa     3000

aatgagagtg agaggcaaca gcaaagacca tctaacattc tgcatttgcc atgctttggc     3060

tccaaattag caaagcatca ctcttccacc accggaactc catctagcga tggaaggcaa     3120

agcccatttg atggggattc aattacgcct actgaaaatc ctaacacatt ggttgagtta     3180

gctactgagg aacaatttaa gagtataaat gtagacccac ttgatgcaga tgaacacagt     3240

ccatttgaat tccttcaaag agggaccaat gtacaggacc aggtacaaga ctgcttacta     3300

cttcaggcc                                                             3309


<210>  6069
<211>  1155
<212>  DNA
<213>  Homo Sapiens

<400>  6069
cagcagcacc accttgtgga gtacatggaa cgccgactag ctgctttaga ggaacggctg       60

gcccagtgcc aggaccagag tagtcggcat gctgctgagc tgcgggactt caagaacaag      120

atgctgccac tgctggaggt ggcagagaag gagcgggagg cactcagaac tgaggccgac      180

accatctccg ggagagtgga tcgtctggag cgggaggtag actatctgga gacccagaac      240

ccagctctgc cctgtgtaga gtttgatgag aaggtgactg gaggccctgg gaccaaaggc      300

aagggaagaa ggaatgagaa gtacgatatg gtgacagact gtggctacac aatctctcaa      360

gtgagatcaa tgaagattct gaagcgattt ggtggcccag ctggtctatg gaccaaggat      420

ccactggggc aaacagagaa gatctacgtg ttagatggga cacagaatga cacagccttt      480

gtcttcccaa ggctgcgtga cttcaccctt gccatggctg cccggaaagc ttcccgagtc      540

cgggtgccct tcccctgggt aggcacaggg cagctggtat atggtggctt tctttatttt      600

gctcggaggc ctcctggaag acctggtgga ggtggtgaga tggagaacac tttgcagcta      660

atcaaattcc acctggcaaa ccgaacagtg gtggacagct cagtattccc agcagagggg      720

ctgatccccc cctacggctt gacagcagac acctacatcg acctggcagc tgatgaggaa      780

ggtctttggg ctgtctatgc cacccgggag gatgacaggc acttgtgtct ggccaagtta      840

gatccacaga cactggacac agagcagcag tgggacacac catgtcccag agagaatgct      900

gaggctgcct ttgtcatctg tgggaccctc tatgtcgtct ataacacccg tcctgccagt      960

cgggcccgca tccagtgctc ctttgatgcc agcggcaccc tgacccctga acgggcagca     1020

ctcccttatt ttccccgcag atatggtgcc catgccagcc tccgctataa cccccgagaa     1080

cgccagctct atgcctggga tgatggctac cagattgtct ataagctgga gatgaggaag     1140

aaagaggagg aggtt                                                      1155


<210>  6070
<211>  342
<212>  DNA
<213>  Homo Sapiens

<400>  6070
actcccccga cctgctactc ccgcatgcgg gccctgagcc aggagatcac ccgcgacttc       60

aacctcctgc aggtctcgga gccctcggag ccatgtgtga gatacctgcc caggctgtac      120

ctggacatac acaattactg tgtgctggac aagctgcggg actttgtggc ctcgcccccg      180

tgttggaaag tggcccaggt agattccttg aaggacaaag cacggaagct gtacaccatc      240

atgaactcgt tctgcaggag agatttggta ttcctgttgg atgactgcaa tgccttggaa      300

tacccaatcc cagtgactac ggtcctgcca gatcgtcagc gc                         342


<210>  6071
<211>  1152
<212>  DNA
<213>  Homo Sapiens

<400>  6071
aaggtgattc tggataaata ctacttcctc tgcgggcagc ctctccactt catcccgagg       60

aagcagctgt gtgacggaga gctggactgt cccttggggg aggacgagga gcactgtgtc      120

aagagcttcc ccgaagggcc tgcagtggca gtccgcctct ccaaggaccg atccacactg      180

caggtgctgg actcggccac agggaactgg ttctctgcct gtttcgacaa cttcacagaa      240

gctctcgctg agacagcctg taggcagatg ggctacagca gcaaacccac tttcagagct      300

gtggagattg gcccagacca ggatctggat gttgttgaaa tcacagaaaa cagccaggag      360

cttcgcatgc ggaactcaag tgggccctgt ctctcaggct ccctggtctc cctgcactgt      420

cttgcctgtg ggaagagcct gaagaccccc cgtgtggtgg gtggggagga ggcctctgtg      480

gattcttggc cttggcaggt cagcatccag tacgacaaac agcacgtctg tggagggagc      540

atcctggacc cccactgggt cctcacggca gcccactgct tcaggaaaca taccgatgtg      600

ttcaactgga aggtgcgggc aggctcagac aaactgggca gcttcccatc cctggctgtg      660

gccaagatca tcatcattga attcaacccc atgtacccca aagacaatga catcgccctc      720

atgaagctgc agttcccact cactttctca ggcacagtca ggcccatctg tctgcccttc      780

tttgatgagg agctcactcc agccacccca ctctggatca ttggatgggg ctttacgaag      840

cagaatggag ggaagatgtc tgacatactg ctgcaggcgt cagtccaggt cattgacagc      900

acacggtgca atgcagacga tgcgtaccag ggggaagtca ccgagaagat gatgtgtgca      960

ggcatcccgg aagggggtgt ggacacctgc cagggtgaca gtggtgggcc cctgatgtac     1020

caatctgacc agtggcatgt ggtgggcatc gttagctggg gctatggctg cgggggcccg     1080

agcaccccag gagtatacac caaggtctca gcctatctca actggatcta caatgtctgg     1140

aaggctgagc tg                                                         1152


<210>  6072
<211>  495
<212>  DNA
<213>  Homo Sapiens

<400>  6072
aactataata tcaacgtcaa tgatgacaac aacaatgctg gaagtgggca gcagtcagtg       60

agtgtcaaca atgaacacaa tgtggccaat gttgacaata acaacggatg ggactcctgg      120

aattccatct gggattatgg aaatggcttt gctgcaacca gactctttca aaagaagaca      180

tgcattgtgc acaaaatgaa caaggaagtc atgccctcca ttcaatccct tgatgcactg      240

gtcaaggaaa agaagcttca gggtaaggga ccaggaggac cacctcccaa gggcctgatg      300

tactcagtca acccaaacaa agtcgatgac ctgagcaagt tcggaaaaaa cattgcaaac      360

atgtgtcgtg ggattccaac atacatggct gaggagatgc aagaggcaag cctgtttttt      420

tactcaggaa cgtgctacac gaccagtgta ctatggattg tggacatttc cttctgtgga      480

gacacggtgg agaac                                                       495


<210>  6073
<211>  333
<212>  DNA
<213>  Homo Sapiens

<400>  6073
ccttcccaga tgctcctgga gaacttctca gccgccatcc caggccaccg atgctggaca       60

cacatgctgg acaatggctc tgcggtttcc acaaacatga cccccaaggc ccttctgacc      120

atctccatcc cgccaggccc caaccagggg ccccaccagt gccgccgctt ccgccagcca      180

cagtggcagc tcttggaccc caatgccacg gccaccagct ggagcgaagc tgacacggag      240

ccgtgtgtgg acggctgggt ctatgaccgc agcgtcttca cctccaccat cgtggccaag      300

tgggacctgg tgtgcagctc ccagggcttg aag                                   333


<210>  6074
<211>  195
<212>  DNA
<213>  Homo Sapiens

<400>  6074
agcagcttca ccatcgacct gccctggggc ggctgctacc atgagtggaa cacagaacac       60

tgtatggagt tccagaagac caacggctcc ctgaatggta cctctgagaa tgccacctct      120

cctgtcatcg agttctggga gcggcgggtc ttgaagatct ctgatgggat ccagcacctg      180

ggggccctgc gctgg                                                       195


<210>  6075
<211>  2232
<212>  DNA
<213>  Homo Sapiens

<400>  6075
aggggcaccc cgctcctggc gcggcctgcg ccgcccggtg cctcccgcta cagtctctac       60

acgacgggat ggcgcccgcg gctgcgcccg gggccgcaca aggccctctg tgcctatgtg      120

gtgcacagga atgtgacctg catcctacag gagggagcgg agagctacgt aaaggctgaa      180

taccggcagt gtagatgggg gcccaagtgc cccgggacag tcacgtaccg cacagtactc      240

agacccaaat acaaggttgg ctacaagaca gtgacagacc tcgcctggcg ttgctgtccc      300

ggcttcactg ggaaacgctg ccctgagcac ctcacggacc atggggctgc ctcaccccag      360

ctggagcctg agcctcagat tccttcaggg cagctggacc caggccccag gcccccttcc      420

tacagcagag cagcccccag ccctcatgga aggaaaggcc cagggctgtt tggtgagcgg      480

ctggaacgcc tggagggtga tgtccagcgc ctggctcaaa catatggtac cctcagtggc      540

ctggtggcta gccacgagga tcccaacagg atgactggtg gccccagggc tcctgctgtc      600

cctgtgggct ttggggtcat ccctgagggg cttgtgggcc caggagacag agccagaggg      660

ccactaacac ctcccttaga cgagatccta agcaaggtga cagaggtgag caacactctt      720

cagaccaagg tgcagcttct agacaaggtg catgggctgg cacttggcca tgaggcccac      780

ctgcagcggc tgcgggaagc cccaccatcc ccgctcacct ccctggccct gctggaggag      840

tacgtggacc gacggctgca ccgactctgg gggagcctgc tggatggctt tgagcagaag      900

ctgcaaggcg tccagagtga gtgtgacctg cgggtgcagg aggtacggcg gcaatgtgag      960

gagggtcagg ctgccagccg gaggctgcac cagagcctcg atggccggga gctggccctg     1020

cgccaggagc tgtcacagct gggcagccag ctgcagggcc tgagcgtgtc tggcaggggc     1080

agctgctgtg ggcaactagc cttgatcaat gcccgtatgg atggccttga gagggccctg     1140

caggcagtca ccgagaccca aaggggcccc ggtgccccgg ccggggatga gcttacgagg     1200

ctctctgctg ccatgctcga gggaggtgtg gacgggctgc ttgagggtct ggagacgctc     1260

aatgggacag agggtggagc aaggggatgc tgtctgaggt tggacatggg ggggtgggga     1320

gtgggcggct ttgggaccat gctggaagag cgcgtgcaga gcctcgagga gcgcctagca     1380

acattggctg gggagctaag ccatgacagc gcctctccgg gcaggtcagc tcggcccctt     1440

gtgcagacag agctggctgt gctagagcaa cggttggtct cactggagac ttcgtgcacc     1500

ccgagcacca cctcagccat cctggacaac ctcgtggcag aggtgaaggc ctggcagagc     1560

cggagcgagg ccctcctacg ccaggtggcc agccacgcag cactgctcca gcagctcaat     1620

ggcactgtgg ccgaggtcca gggacagctg gcagaaggga cgggcagctc acttcaaggc     1680

gagatcactc tgctcaaggt caatctgaac tcagtgagca agtcgctcac aggcctcagt     1740

gactctgtca gccagtactc tgatgccttc ttggctgcca acacgtccct ggatgagcgg     1800

gaacgcaagg tggaagccga agtccaggcc atccaggagc aggtcagcag ccaaggctcc     1860

aggcttcagg ctggccacag gcaggtcctg aacctgcgtg gggagctgga gcaactcaag     1920

gctggtgtgg ccaaggtggc cagtgggctg agccgctgcc aggacacagc ccagaaactt     1980

cagcacacag tgggacactt tgaccagcgg gtggcacaag tggagggtgc gtgcaggagg     2040

ctgggcctgc tggccgcggg cctggacagc ttgcccactg agccactgag gcccagagag     2100

ggcctgtgga gccatgtgga ccagctgaat cgtacgctgg cccagcacac gcaggacatt     2160

gcccgcctcc gggatgacct actggactgc caggcccagc tggctgagca ggtgcggcca     2220

gggcaagcca ac                                                         2232


<210>  6076
<211>  522
<212>  DNA
<213>  Homo Sapiens

<400>  6076
cagaacgaca cggagcccat cgtgctggag ggcaagtgtc tggtggtgtg cgactcgaac       60

ccggccacgg actccaaggg ctcctcttcc tccccgctgg ggatatcggt ccgggcggcc      120

aactccaagg tcgccttctc ggcggtgcgg agcaccaacc acgagccatc cgagatgagc      180

aacaagacgc gcatcattta cttcgatcag atcctggtga atgtgggtaa ttttttcaca      240

ttggagtctg tctttgtagc accaagaaaa ggaatttaca gtttcagttt tcacgtgatt      300

aaagtctacc agagccaaac tatccaggtt aacttgatgt taaatggaaa accagtaata      360

tctgcctttg cgggggacaa agatgttact cgtgaagctg ccacgaatgg tgtcctgctc      420

tacctagata aagaggataa ggtttaccta aaactggaga aaggtaattt ggttggaggc      480

tggcagtatt ccacgttttc tggctttctg gtgttccccc ta                         522


<210>  6077
<211>  735
<212>  DNA
<213>  Homo Sapiens

<400>  6077
tggctgacga cgggcgcccc cgagccgccg ccgctgtccg gagccccaca ggacggcatc       60

agaattaatg taactacact gaaagatgat ggggacatat ctaaacagca ggttgttctt      120

aacataacct atgagagtgg acaggtgtat gtaaatgact tacctgtaaa tagtggtgta      180

acccgaataa gctgtcagac tttgatagtg aagaatgaaa atcttgaaaa tttggaggaa      240

aaagaatatt ttggaattgt cagtgtaagg attttagttc atgagtggcc tatgacatct      300

ggttccagtt tgcaactaat tgtcattcaa gaagaggtag tagagattga tggaaaacaa      360

gttcagcaaa aggatgtcac tgaaattgat attttagtta agaaccgggg agtactcaga      420

cattcaaact ataccctccc tttggaagaa agcatgctct actctatttc tcgagacagt      480

gacattttat ttacccttcc taacctctcc aaaaaagaaa gtgttagttc actgcaaacc      540

actagccagt atcttatcag gaatgtggaa accactgtag atgaagatgt tttacctggc      600

aagttacctg aaactcctct cagagcagag ccgccatctt catataaggt aatgtgtcag      660

tggatggaaa agtttagaaa agatctgtgt aggttctgga gcaacgtttt cccagtattc      720

tttcagtttt tgaac                                                       735


<210>  6078
<211>  171
<212>  DNA
<213>  Homo Sapiens

<400>  6078
agtcttgctc cccaatatgt tatgtatgga agccaaaatt acttaataga gactaatata       60

acttctgata atcataaagg caattcaacc ctttctgtgc caaagagatg tgatgcagat      120

gctcctgaag atcagtgtac tgttacccgg acatacctat tccttcacaa g               171


<210>  6079
<211>  237
<212>  DNA
<213>  Homo Sapiens

<400>  6079
gtcttgaaag atatgaagct tttgcgccag agcttggcca ctctcctaat tacctcccag       60

atcctcaacc aaattatgga atcttttctt ccttattggc tccaaaggaa gcatggtgtg      120

cgggtgaaga ggaaggtgca ggctttaaag gcagacattg atgctacatt atatgaacaa      180

gtcatcctgg aaaaagaaat gggaacttat ttgggcacct ttgatgatta cttggag         237


<210>  6080
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  6080
ccaggagtcg tgcctaaaga catagaggac atctatctta gcatctgtgt gtttggccaa       60

tacaaaaaga cacaatgtgt cccagccact tttcccctgg tcttcaatgc cagaatggtg      120

tttgaaaagg tgttcccgga cgcagtagat cctggagatg tggttacaca gcttgaatat      180

gatacagcag tgttcgagtt gatacagcta gttccaccag tgggtgaaac actgtctacg      240

tatgacgaaa atacacgaga tttcatgttt ccgggtccaa accaaatgtc tggacaccat      300

gattcaaacc gccaggttac catgaggagg atttctggcc ttcgaggaaa tgctccaagg      360

ctggaatttt ctacgacttc agtgattact gaatgtctga taagttcaag gaaatgccac      420

actcaggata aatttattta ccatttggct ccagttgaaa aatcacatgg cagactgcaa      480

aacagaacat caagatcaca aaagaaaaaa tccaagtcac ctgagagaag taaatactgt      540

ataaatgcaa aaaactacga acagcctaca atttcttcaa aatcacactc tccatctccc      600

tacacaaaaa gacgcatgtg tgagctatct gaagacacca ggcggcggct ggcccattta      660

aatctgggac cctatgagtt caaaaaagaa acagataaac ctccatttgt gattagacat      720

gttgatcccc caagtcccag ggctgatact ttattgggat cttctggaag agactgtgaa      780

agagatggat ggtcaagggt gcacaatgat cattctcatc ttggctgctg ccgacccaag      840

gattataagg ttatcaggac accccatggg agagacttcg atgactcttt agaaaaatgt      900

gaagagtatt tgagcccaag gtcgtgtagt aagccccggc attcagcgag gaccttgcta      960

gtccattcag caccctcaac aatgccaaag cattctccaa gccctgtgtt aaatagagct     1020

tctctcaggg aaagatttca ttctgattgg tgttcacctt caaactgcga tgagatccat     1080

gaccgggatg agagagacct agagaaagat gatgaactgg aactgaaaag aagtctttta     1140

tgtagagact ctgcctatga cagtgacccc gagtatagct catgtcagca gccacgtggc     1200

actttccatt tggatgacgg tgaatactgg tccaacaggg cagcctctta taagggaaaa     1260

tcccaccgac ccatctttga gaacagcatg gacaagatgt acaggaactt atacaaaaag     1320

gcctgtagtt ctgcttcaca tacacaggaa agcttc                               1356


<210>  6081
<211>  576
<212>  DNA
<213>  Homo Sapiens

<400>  6081
gctttgatcc ctgaaccaga agtgaaaatt gaagttctcc agaagccatt catctgccat       60

cgcaagacca aaggagggga tttgatgttg gtccactatg aaggctactt agaaaaggac      120

ggctccttat ttcactccac tcacaaacat aacaatggtc agcccatttg gtttaccctg      180

ggcatcctgg aggctctcaa aggttgggac cagggcttga aaggaatgtg tgtaggagag      240

aagagaaagc tcatcattcc tcctgctctg ggctatggaa aagaaggaaa aggtaaaatt      300

cccccagaaa gtacactgat atttaatatt gatctcctgg agattcgaaa tggaccaaga      360

tcccatgaat cattccaaga aatggatctt aatgatgact ggaaactctc taaagatgag      420

gttaaagcat atttaaagaa ggagtttgaa aaacatggtg cggtggtgaa tgaaagtcat      480

catgatgctt tggtggagga tatttttgat aaagaagatg aagacaaaga tgggtttata      540

tctgccagag aatttacata taaacacgat gagtta                                576


<210>  6082
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  6082
cgctggctgc tctgtaacgg cagtttgttc cgatacaagc acccgtctga ggaggagctt       60

cgggccctgg cggggaagcc gaggcccaga ggcaggaaag agcggtgggc caatggcctt      120

agtgaggaga agccactgtc tgtgccccga gatgccccgt tccagctgga gacctgcccc      180

ctcacgaccg tggatgccct ggtcctgcgc                                       210


<210>  6083
<211>  1107
<212>  DNA
<213>  Homo Sapiens

<400>  6083
aaagacgagg gcttcgcggt gaaggcgctg tggggccgca cgcaggaaga agcggaggag       60

ctggccaagg agatgagtgt ccccttctac actagccgca ttgatgaggt gctgctgcat      120

caggacgtgg acttggtgtg cattaacctg ccgccgcccc tcaccagaca gatcgctgtc      180

aaaaccctag gcatcggcaa gaacgtcatc tgcgaccgca cggccacgcc gctggacgct      240

ttccgcatga cctcggccgc ccactactac cccaagctca tgagcatcat gggcaacgtg      300

ctgcgcttcc tgccggcttt cgtgcgcatg aagcagctga tcgaggaggg ctacgtgggc      360

gagccgctgg tgtgtgaggt gcaggtgcac ggcggcagcc tgctgggcaa gaagtacaac      420

tggagctgcg acgacttgat gggcggcggc ggcctgcact ccgtgggcac ctacatcatc      480

gacctgctca ccttcctcac cggccaaaag gccgtcaagg tccacgggct gctcaagacc      540

ttcgtgaagc agactgacca catcaagggc atccgacaga tcaccagcga tgacttctgc      600

accttccaga tggtgctgga gggcggggtg tgctgcaccg tcaccctcaa cttcaacgtg      660

cccggcgagt tcaagcagga tgtcactgtg gtgggctcag ccgggcgcct gctggccgtg      720

ggcaccgacc tgtacgggca gcgcaacagc gccccggagc aggagctgct ggtgcaggac      780

gccacgccgg tgagcaactc cctgcttccg gagaaggcct tcagcgacat cccctcgccc      840

tacctgcgcg gcaccatcaa gatgatgcag gcggtgcgcc aggccttcca ggaccaggac      900

gaccggcgca cgtgggatgg gcggcccctc accatggccg ccaccttcga cgactgcctg      960

tatgccttgt gcgtggtgga caccatcaag aggtccagcc agacgggcga gtggcagaac     1020

attgccatca tgaccgagga gccggagctg agccccgcct acctgatcag cgaggccatg     1080

cgccgcagca ggatgtccct ctactgt                                         1107


<210>  6084
<211>  1131
<212>  DNA
<213>  Homo Sapiens

<400>  6084
cgcttgctca actacttcac atggccaacc acaacgtcca ttgaggttca atatgtggaa       60

aagatggagt tcccagctgt gacattttgt aatttgaaca ggttccaaac agatgctgta      120

gccaaatttg gtgttatttt tttcttatgg cacattgtat ccaaagtcct ccatcttcaa      180

gaaattactg ccaattccac tggctctaga gaggctactg attttgctgc aagtcaccaa      240

aacttcagca ttgtggaatt tatcaggaac aaaggttttt atctcaacaa tagcactttg      300

ttggactgtg agttttttgg aaagccatgt agcccaaagg attttgcaca tgtcttcact      360

gaatatggaa attgttttac ttttaatcat ggtgaaactc tccaagcaaa gagaaaagtg      420

agtgtctctg gaagaggttt gagcttactc ttcaatgtga atcaggaggc attcactgat      480

aacccagccc ttggtttcgt tgatgctggg atcatctttg ttatccattc accaaagaag      540

gtgccacagt ttgatgggtt aggcttgttg tcacctgtgg gaatgcacgc aagggtaacc      600

atccgccaag tgaagacagt tcatcaagaa tacccttggg gagaatgcaa tcctaacatc      660

aagctgcaga attttagcag ctacagcact tctggttgct tgaaggaatg caaagcccag      720

cacataaaaa agcaatgtgg atgtgtgcct tttcttcttc ctggatatgg gatagaatgt      780

gacctacaaa agtacttcag ctgtgtttct cctgtacttg accacattga atttaaggat      840

ttatgtacag taggaacaca taactctagc tgccccgttt cttgtgaaga aatagaatac      900

ccggccacta tttcttattc ctcttttcca agtcaaaaag ctttgaaata tctttccaag      960

aagttgaatc aaagccggaa atacatcagg gagaatcttg taaaaattga aattaactat     1020

agtgacctaa actataagat aacccagcag caaaaggcgg tgagtgtgtc tgagttactt     1080

gcagatcttg gtggtcagct gggtctattt tgtggggcca gtctgatcac g              1131


<210>  6085
<211>  267
<212>  DNA
<213>  Homo Sapiens

<400>  6085
agccgcatcc tgtacacaga tatggtagca tgtgtggtac cttctgaatg cgtgaaacac       60

tgtggcgttg atgttggctg caccaactac gcatacccca cgatggtgct ggaactgatg      120

ccccaaggac tgcgaggcct gatgctttcg gtcatgctgg cctctctcat gagctccctg      180

acctccatct tcaacagcgc cagcaccctc ttcaccattg acctctacac caagatgcgg      240

aagcaagcgt cggagaaaga gctcctg                                          267


<210>  6086
<211>  384
<212>  DNA
<213>  Homo Sapiens

<400>  6086
gggctcgaaa ccgaaagtcc cgtccggacc ctccaagtgg agaccctggt ggagccccca       60

gaaccatgtg ccgagcccgc tgcttttgga gacacgcttc acatacacta cacgggaagc      120

ttggtagatg gacgtattat tgacacctcc ctgaccagag accctctggt tatagaactt      180

ggccaaaagc aggtgattcc aggtctggag cagagtcttc tcgacatgtg tgtgggagag      240

aagcgaaggg caatcattcc ttctcacttg gcctatggaa aacggggatt tccaccatct      300

gtcccagcgg atgcagtggt gcagtatgac gtggagctga ttgcactaat ccgagccaac      360

tactggctaa agctggtgaa gggc                                             384


<210>  6087
<211>  1470
<212>  DNA
<213>  Homo Sapiens

<400>  6087
ggctcccctg ccctccgctg gtacaggacc tcctgccact tgaccaaggc cgtccctggc       60

aacccactgg ggtacctgag cttcctggcc aaggatgctc agggactggc cctgatccat      120

gcccgctggg atgcgcatag gaggctgcag gcatgtagct gggaggatga gccggagctc      180

accgcagcct acggtgctct ctgtgctcat gagactgcct ggggctcctt catccacacc      240

cccggacccg agctgcagag agcactggcc actcttcaga gtcagtggga ggcatgccga      300

gcgcttgagg agagtccagc aggggccagg aagaagcgag cagcagggca gagtggagtc      360

cctggtggag ggcaccagcg agagaagaga ggatggacca tgcctggcac actgtggtgt      420

ggagttggag attctgctgg gaactcctcg gagctggggg tcttccaggg acctgatctc      480

tgttgccggg aacatgaccg ctgcccacag aacatctcac ccttgcagta caactatggc      540

atccgaaact accgattcca caccatctcc cactgtgact gtgacaccag gtttcagcaa      600

tgcctacaga atcagcacga ctccatctcg gacatcgtgg gcgtggcctt cttcaacgtg      660

ctggagatcc cctgctttgt gctggaggag caggaggcgt gtgtggcgtg gtactggtgg      720

ggcgggtgta ggatgtatgg cacagtgccc ctcgctcgcc tgcagcccag gaccttctac      780

aatgcctcct ggagctcccg ggccacctcc ccaactccca gctcccggag cccagcccct      840

cccaagcctc gacagaagca gcaccttcgg aaggggccac cacatcagaa agggtccaag      900

cgccccagca aagccaacac cacagccctc caggacccta tggtctctcc caggcttgat      960

gtggccccca caggcctcca gggcccacag ggtggcctaa aacctcaggg tgcccgctgg     1020

gtctgccgca gcttccgccg ccacctggac cagtgtgagc accagattgg gccccgggaa     1080

atcgagttcc agctgctcaa cagcgcccaa gagcccctct tccactgcaa ctgcacgcgc     1140

cgtctggcac gcttcctgag gctccacagc ccacccgagg ttaccaacat gctttgggag     1200

ctgctgggca caacctgctt caagctggcc cctccactgg actgtgtgga aggcaaaaac     1260

tgttccagag accctagggc catcagggtg tcagcccggc acttgcggag gcttcagcag     1320

aggcgacacc agctccagga taaaggcaca gatgagaggc agccatggcc ttcagagccc     1380

ctgagaggcc ccatgtcatt ctacaaccag tgcctgcagc taacccaggc agccaggaga     1440

cccgacaggc agcagaagtc ctggagccag                                      1470


<210>  6088
<211>  1404
<212>  DNA
<213>  Homo Sapiens

<400>  6088
gggtctgatg agcctggccc agagggcctc acctccacct ccctgctaga cctcctgctg       60

cccactggct tggagccact ggactcagag gagcctagtg agaccatggg cctgggagct      120

gggctgggag cccctggctc aggcttcccc agcgaagaga atgaagagtc tcggattctg      180

cagccaccac agtacttctg ggaagaggag gaagagctga atgactcaag tctggacctg      240

ggacccactg cagattatgt ttttcctgac ttaactgaga aggcaggttc cattgaagac      300

actagccagg ctcaagagct gccaaacctc ccctctccct tgcccaagat gaatctggtt      360

gagcctccct ggcatatgcc tcccagagag gaggaagaag aggaagagga agaggaggag      420

agggagaagg aagaggtaga gaaacaagag gaggaggaag aggaggagct gctccctgtg      480

aatggatccc aagaagaagc caagcctcag gtccgtgact tttctctcac cagcagcagc      540

cagaccccag gggccaccaa aagcaggcat gaagactccg gggaccaggc ctcatcaggt      600

gtggaggtgg agagcagcat ggggcccagc ttgctgctgc cttcagtcac cccaactaca      660

gtgactccgg gggaccagga ctccaccagc caagaggcag aggccacagt gctgccagct      720

gcagggcttg gggtagagtt cgaggctcct caggaagcaa gcgaggaagc cactgcagga      780

gcagctggtt tgtctggcca gcacgaggag gtgccggcct tgccttcatt ccctcaaacc      840

acagctccca gtggggccga gcacccagat gaagatcccc ttggctctag aacctcagcc      900

tcttccccac tggcccctgg agacatggaa ctgacacctt cctctgctac cttgggacaa      960

gaagatctca accagcagct cctagaaggg caggcagctg aagctcaatc caggataccc     1020

tgggattcta cgcaggtgat ctgcaaggac tggagcaatc tggctgggaa aaactacatc     1080

attctgaaca tgacagagaa catagactgt gaggtgttcc ggcagcaccg ggggccacag     1140

ctcctggccc tggtggaaga ggtgctgccc cgccatggca gtggccacca tggggcctgg     1200

cacatctctc tgagcaagcc cagcgagaag gagcagcacc ttctcatgac actggtgggc     1260

gagcaggggg tggtgcccac tcaagatgtc ctttccatgc tgggtgacat ccgcaggagc     1320

ctggaggaga ttggcatcca gaactattcc acaaccagca gctgccaggc gcgggccagc     1380

caggtgcgca gcgactacgg cacg                                            1404


<210>  6089
<211>  1956
<212>  DNA
<213>  Homo Sapiens

<400>  6089
caggccccag cacccacagt caacactcac tttgggaagc taaggggtgc ccgagtacca       60

ctgcccagtg agatcctggg gcctgtggac caatacctgg gggtgcccta cgcagctccc      120

ccgatcggcg agaaacgttt cctgccccct gaaccacccc catactggtc gggcatccgg      180

aacgccacac actttccacc agtgtgcccc cagaacatcc acacagctgt gcccgaagtc      240

atgctgccgg tctggttcac tgccaacttg gatatcgtcg ctacttacat ccaggagccc      300

aacgaagact gtctctacct gaacgtctat gtgccgacgg aggatggatc cggcgctaag      360

aaacagggcg aggacttagc ggataatgac ggggatgaag atgaagacat ccgggacagt      420

ggtgctaaac ccgtcatggt ctacatccac ggaggctctt acatggaagg gacaggcaac      480

atgattgatg gcagcatcct cgccagttat ggcaatgtca tcgtcatcac cctcaactat      540

cgggttggag tgctaggttt cctgagtact ggagatcagg ctgccaaggg caactatggg      600

ctccttgacc agatccaggc cctccgctgg gtgagcgaga atattgcctt cttcggggga      660

gacccccgcc ggatcactgt ctttggctcg ggcattggtg catcctgcgt cagcctccta      720

acgttgtcac atcactcaga gggacttttc cagagagcca tcatccaaag tggctctgct      780

ctgtccagct gggctgtgaa ctaccaacca gtgaagtaca ccagcctgct ggcagacaaa      840

gtgggctgta atgtgctgga caccgtggat atggtggact gtcttcggca aaagagtgcc      900

aaggagctgg tagagcagga catccagcca gcccgctacc acgtggcctt tggccctgtg      960

attgatggtg atgtcattcc tgatgaccct gagatcctca tggagcaggg cgagttcctc     1020

aactatgaca tcatgctagg tgtcaaccag ggcgagggtc tcaagtttgt ggaaggggtg     1080

gtggaccctg aggatggtgt ctctggcact gactttgact attccgtctc caattttgtg     1140

gacaatctgt atggctatcc tgagggtaag gacaccctgc gagagaccat caagttcatg     1200

tatacagact gggcagaccg tgacaaccct gagacccgcc gtaaaacact ggtggcactc     1260

ttcactgacc accagtgggt ggagccctca gtggtgacag ccgatctgca tgcccgctac     1320

ggctcgccta cctacttcta cgccttctat catcactgcc agagcctcat gaagcctgct     1380

tggtcagatg cagctcatgg ggatgaagta ccctatgttt ttggggttcc tatggtaggc     1440

cccactgacc ttttcccctg caacttctcc aagaatgatg ttatgctcag tgctgtcgtc     1500

atgacctatt ggaccaactt tgccaagact ggggatccca acaagccggt cccccaggac     1560

accaagttca ttcacaccaa ggccaaccgc tttgaggaag tggcctggtc caaatacaat     1620

ccccgagacc agctctacct tcacatcggg ctgaaaccaa gggtccgaga tcattaccgg     1680

gccactaagg tggccttttg gaaacatctg gtgccgcacc tatacaacct gcatgacatg     1740

ttccactata cgtccaccac caccaaagtg ccgcctccgg ataccaccca cagctcccac     1800

atcacccgca ggcccaatgg caagacctgg agcaccaagc ggccagccat ctcacctgcc     1860

tacagcaacg agaatgccca ggggtcctgg aacggggacc aggatgcagg gccactcctg     1920

gtggagaacc ctcgtgacta ctccactgaa ttaagt                               1956


<210>  6090
<211>  195
<212>  DNA
<213>  Homo Sapiens

<400>  6090
atggaatcag caagagaaaa catcgacctt caacctggaa gctccgaccc caggagccag       60

cccatcaacc tgaaccatta cgccaccaag aagagcgtgg cggagagcat gctggacgtg      120

gccctgttca tgtccaacgc catgcggctg aaggcggtgc tggagcaggg accatcctct      180

cactactaca ccacc                                                       195


<210>  6091
<211>  1446
<212>  DNA
<213>  Homo Sapiens

<400>  6091
atagatgaaa cacgggcgca tctgttgttg aaagaaaaga tgatgcggct gggggggcgg       60

ctggtgctga acaccaagga ggagctggcc aatgagaggc tcatgacgct caaaatcgct      120

gagatgaagg aggccatgag gaccctgata ttcccaccca gcatgcactt tttccaggcc      180

aagcatctca ttgagagaag tcaagtgttt aatattctaa ggatgatgcc aaaaggggct      240

gccttgcacc tccatgacat tggcatcgtg actatggact ggctggtgag gaatgtcacc      300

tacaggcctc actgccacat ctgtttcacc ccaaggggga tcatgcagtt cagatttgct      360

cacccaactc cccgtccatc agaaaaatgt tccaagtgga ttctgctgga ggattatcgg      420

aagcgggtgc agaacgtcac tgagtttgat gacagcttgc tgaggaattt cactctggtg      480

acccagcacc cggaggtgat ttacacaaac caaaatgttg tctggtcgaa atttgaaacc      540

atcttcttca ccatctctgg tctcatccat tacgcaccag tgttcagaga ctatgtcttc      600

cggagcatgc aggagttcta cgaggacaac gtgctctaca tggagatcag agccaggctg      660

ctgccggtgt atgagctcag tggagagcac catgacgaag agtggtcagt gaagacttac      720

caggaagtag ctcagaagtt tgtggaaact caccctgagt ttattggaat caaaatcatt      780

tattcggatc acagatccaa agatgtggct gtcatcgcag aatccatccg aatggccatg      840

gggctccgaa tcaagttccc cacggtggtg gcagggtttg acctggtggg gcatgaggac      900

actggccact ccttgcatga ctacaaggaa gctctgatga tccccgccaa ggatggcgtt      960

aagctgcctt acttcttcca cgccggagaa acagactggc agggtacttc catagacagg     1020

aacattctgg atgctctgat gctgaacact accagaatcg gccatggatt tgctttgagc     1080

aaacaccccg cagtcaggac ttactcctgg aaaaaggaca tccccataga agtctgtccc     1140

atctctaacc aggtgctgaa actggtgtct gacttgagga accaccctgt agccactctg     1200

atggccactg ggcaccccat ggtgatcagc tctgatgacc cagctatgtt tggtgccaaa     1260

ggcttgtcct atgatttcta tgaggtcttc atgggcattg gggggatgaa ggctgacctg     1320

aggaccctca aacagctggc catgaactct atcaagtaca gtaccctgtt ggagagtgag     1380

aaaaatactt tcatggaaat ctggaagaag agatgggata agttcatagc agatgtggct     1440

acaaag                                                                1446


<210>  6092
<211>  369
<212>  DNA
<213>  Homo Sapiens

<400>  6092
aacctggttc agtttggggt gatgatcgag aagatgacag gcaagtccgc cctgcagtac       60

aacgactatg gctgttactg cggcatcggt ggctcccact ggccggtgga ccagactgac      120

tggtgctgcc acgcccacga ctgctgctac gggcgtctgg agaagctggg ctgtgagccc      180

aaactggaaa agtatctttt ctctgtcagc gaacgtggca ttttctgcgc cggcaggacc      240

acctgccagc ggctgacctg cgagtgtgac aagagggctg ccctctgctt tcgccgcaac      300

ctgggcacct acaaccgcaa atatgcccat tatcccaaca agctgtgcac cgggcccacc      360

ccgccctgc                                                              369


<210>  6093
<211>  1356
<212>  DNA
<213>  Homo Sapiens

<400>  6093
tgcccaaccc ggggctccgt cctcttggcc caagagctac cccagcagct gacatccccc       60

gggtacccag agccgtatgg caaaggccaa gagagcagca cggacatcaa ggctccagag      120

ggctttgctg tgaggctcgt cttccaggac ttcgacctgg agccgtccca ggactgtgca      180

ggggactctg tcacaatctc attcgtcggt tcggatccaa gccagttctg tggtcagcaa      240

ggctcccctc tgggcaggcc ccctggtcag agggagtttg tatcctcagg gaggagtttg      300

cggctgacct tccgcacaca gccttcctcg gagaacaaga ctgcccacct tcacaagggc      360

tttctggccc tctaccaaac cgtggctgtg aactatagtc agcccatcag cgaggccagc      420

aggggctctg aggccatcaa cgcacctgga gacaaccctg ccaaggtcca gaaccactgc      480

caggagccct attatcaggc cgcggcagca ggggcactca cctgtgcaac cccagggacc      540

tggaaagaca gacaggatgg ggaggaggtt cttcagtgta tgcctgtctg cggacggcca      600

gtcaccccca ttgcccagaa tcagacgacc ctcggttctt ccagagccaa gctgggcaac      660

ttcccctggc aagccttcac cagtatccac ggccgtgggg gcggggccct gctgggggac      720

agatggatcc tcactgctgc ccacaccgtc taccccaagg acagtgtttc tctcaggaag      780

aaccagagtg tgaatgtgtt cttgggccac acagccatag atgagatgct gaaactgggg      840

aaccaccctg tccaccgtgt cgttgtgcac cccgactacc gtcagaatga gtcccataac      900

tttagcgggg acatcgccct cctggagctg cagcacagca tccccctggg ccccaacgtc      960

ctcccggtct gtctgcccga taatgagacc ctctaccgca gcggcttgtt gggctacgtc     1020

agtgggtttg gcatggagat gggctggcta actactgagc tgaagtactc gaggctgcct     1080

gtagctccca gggaggcctg caacgcctgg ctccaaaaga gacagagacc cgaggtgttt     1140

tctgacaata tgttctgtgt tggggatgag acgcaaaggc acagtgtctg ccagggggac     1200

agtggcagcg tctatgtggt atgggacaat catgcccatc actgggtggc cacgggcatt     1260

gtgtcctggg gcatagggtg tggcgaaggg tatgacttct acaccaaggt gctcagctat     1320

gtggactgga tcaagggagt gatgaatggc aagaat                               1356


<210>  6094
<211>  198
<212>  DNA
<213>  Homo Sapiens

<400>  6094
agtgaggaag ctcccctgag gacaggcctg gaggacctgc aggacctgga cagcctggac       60

acggagaaga gcccgctgta tggcctgcag agccgggtgg aggagctggt ggaggcgccg      120

agggctcagg gtgaccgagg cccacgtgct gtcttcctgc tcacacgctg gcggaaattc      180

tggggcgctc ccgtgact                                                    198


<210>  6095
<211>  681
<212>  DNA
<213>  Homo Sapiens

<400>  6095
ataattggtg gccatacgtg cacccggagc tcccagccgt ggcaggcggc cctgctggcg       60

ggtcccaggc gccgcttcct ctgcggaggc gccctgcttt caggccagtg ggtcatcact      120

gctgctcact gcggccgccc gatccttcag gttgccctgg gcaagcacaa cctgaggagg      180

tgggaggcca cccagcaggt gctgcgcgtg gttcgtcagg tgacgcaccc caactacaac      240

tcccggaccc acgacaacga cctcatgctg ctgcagctac agcagcccgc acggatcggg      300

agggcagtca ggcccattga ggtcacccag gcctgtgcca gccccgggac ctcctgccga      360

gtgtcaggct ggggaactat atccagcccc atcgccaggt accccgcctc tctgcaatgc      420

gtgaacatca acatctcccc ggatgaggtg tgccagaagg cctatcctag aaccatcacg      480

cctggcatgg tctgtgcagg agttccccag ggcgggaagg actcttgtca gggtgactct      540

gggggacccc tggtgtgcag aggacagctc cagggcctcg tgtcttgggg aatggagcgc      600

tgcgccctgc ctggctaccc cggtgtctac accaacctgt gcaagtacag aagctggatt      660

gaggaaacga tgcgggacaa a                                                681


<210>  6096
<211>  567
<212>  DNA
<213>  Homo Sapiens

<400>  6096
agtgcttatt actacaccaa agtgatgtct gagctcttct tacatactcc atcagacact       60

ggagtctcct ttcaggccat cagcagcatg gcggacttct gggattttgc ccagggccca      120

ctactggaca gtttgtattg gaccaaatgg tacaacaacc agagcctggg ccatggctcc      180

cactccttca tctactatga gaacatgctg ctgggggttc cgaggctgcg gcagctaaag      240

gtccgcaatg actcctgtgt ggtgcatgaa gacttccggg aggacattct gagctgctat      300

gatgtctact ctccagacaa agaagaacaa ctcccctttg ggcccttcaa tggcacagcg      360

tggacatacc actcgcagga tgagttgggg ggcttctccc actggggcag gctcacaagc      420

tacagcggag gtggctacta cctggacctt ccaggatccc gacagggtag tgcagaggct      480

ctccgggccc ttcaggaggg gctgtggctg gacaggggca ctcgagtggt gttcatcgac      540

ttctcagtct acaatgccaa tatcaat                                          567


<210>  6097
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  6097
tggtactgct atggattgtg tgccccagcc ccccagatgt tgcgccacca gggtctcctc       60

aagtgccgct gccgcatgct cttcaatgac ctgaaggttt tcttactgcg gcgccctcct      120

caagcgcccc tgcccatgca cggcgacccc cagccccccg gtttggcggc caacaacacc      180

cttccggctc tgggcgccgg ggggtgggca ggctggaggg gcccccgaga agtggtgggc      240

agggagcccc ctcctgtgcc acctccaccc cccttgccac cttcttctgt ggaagatgac      300

tggggtggcc cagccacaga gccacctgcc tcgctgctca gcagtgcctc ctcagatgac      360

ttctgtaagg agaagaccga ggatcgctac tcactgggca gcagcttgga cagtggtatg      420

aggaccccac tctgccgcat ctgcttccag gggccagaac agggggagct gctgagccca      480

tgccgctgtg atggctctgt caagtgcaca caccagcctt gcctcatcaa gtggatcagc      540

gagcggggct gctggagctg cgagctgtgc tactacaagt accacgtcat cgccataagc      600

acaaaaaatc ctctgcagtg gcaggccatc tctctgacgg tcattgagaa ggttcag         657


<210>  6098
<211>  2394
<212>  DNA
<213>  Homo Sapiens

<400>  6098
ttaccagaac tgagtcctca gaaatatttt agtacattgc aaccaggaaa agcctcttta       60

gcttattttt gtcaagctga ttccccaaga acatctgtat ttcttgaaga actgaatgag      120

gctgttagac ctctgcagga ctatggaatt tcagttgcca aggttaattg tgtcaaagaa      180

gaaatatcaa gatactgtgg aaaagaaaag gatttgatga aagcatattt attcaagggc      240

aacatattgc tcagagaatt ccctactgac accttgtttg atgtgaatgc cattgtcgcc      300

catgttctct ttgctcttct ttttagtgaa gtgaaatata ttaccaacct ggaagacctt      360

cagaacatag aaaatgctct gaaaggaaaa gcaaatatta tattctcata tgtaagagcc      420

attggaatac cagagcacag agcagtcatg gaagccgctt ttgtgtatgg gactacatac      480

caatttgtct taaccacaga aattgccctt ttggaaagta ttggctctga ggatgtggaa      540

tatgcacatc tctacttttt tcattgtaaa ctagtcttgg acttgaccca gcaatgtaga      600

agaacactaa tggaacagcc attgactaca ctgaacattc acctgtttat taagacaatg      660

aaagcacctc tgttgactga agttgctgaa gatcctcaac aagtttcaac tgtccatctc      720

caactgggct taccactggt ttttattgtt agccaacagg ctacttatga agctgataga      780

agaactgcag aatgggttgc ttggcgtctt ctgggaaaag caggagttct actcttgtta      840

agggactctt tggaagtgaa cattcctcaa gatgctaatg tggtcttcaa aagagcagaa      900

gagggagttc cagtggaatt tttggtatta catgatgttg atttaataat atctcatgtg      960

gaaaataata tgcacattga ggaaatacaa gaagatgaag acaatgacat ggaaggtcca     1020

gatatagatg ttcaggatga tgaagtggca gaaactgttt tcagagatag gaagagaaaa     1080

ttacctttgg aacttacagt ggaactaaca gaagaaacat ttaatgcaac agtgatggct     1140

tctgacagca tagtactctt ctatgctggt tggcaagcag tatccatggc atttttgcaa     1200

tcctatattg atgtggcagt taaactgaaa ggcacatcta ctatgcttct tactagaata     1260

aactgtgcag attggtctga tgtatgtact aagcaaaatg ttactgaatt tcctatcata     1320

aagatgtaca agaaaggcga gaacccagta tcttatgctg gaatgttagg aaccaaagat     1380

ctcctaaaat ttatccagct caacaggatt tcatatccag tgaatataac atcgatccaa     1440

gaagcagaag aatatttaag tggggaatta tataaagacc tcatcttgta ttctagtgtg     1500

tcagtattgg gactatttag tccaaccatg aaaacagcaa aagaagattt tagtgaagca     1560

ggaaactacc taaaaggata tgttatcact ggaatttatt ctgaagaaga tgttttgcta     1620

ctgtcaacca aatatgctgc aagtcttcca gccctgctgc ttgccagaca cacagaaggc     1680

aaaatagaga gcatcccact agctagcaca catgcacaag acatagttca aataataaca     1740

gatgcactac tggaaatgtt tccggaaatc actgtggaaa atcttcccag ttatttcaga     1800

cttcagaaac cattattgat tttgttcagt gatggcactg taaatcctca atataaaaaa     1860

gcaatattga cactggtaaa gcagaaatac ttggattcat ttactccatg ctggttaaat     1920

ctaaagaata ctccagtggg gagaggaatc ttgcgggcat attttgatcc tctgcctccc     1980

cttcctcttc ttgttttggt gaatctgcat tcaggtggcc aagtatttgc atttccttca     2040

gaccaggcta taattgaaga aaaccttgta ttgtggctga agaaattaga agcaggacta     2100

gaaaatcata tcacaatttt acctgctcaa gaatggaaac ctcctcttcc agcttatgat     2160

tttctaagta tgatagatgc cgcaacatct caacgtggca ctaggaaagt tcccaagtgt     2220

atgaaagaaa cagatgtgca ggagaatgat aaggaacaac atgaagataa atcggcagtc     2280

agaaaagaac cgattgaaac tctgagaata aagcattgga atagaagtaa ttggtttaaa     2340

gaagcagaaa aatcatttag acgtgataaa gagttaggat gctcaaaagt gaac           2394


<210>  6099
<211>  180
<212>  DNA
<213>  Homo Sapiens

<400>  6099
gcacctgccc accggggacg aggaggctgg accctcaata gtgctggcta ccttctgggt       60

cccgtcctcc accttcccca aatgggtgac caagacggaa agagggagac agcccttgag      120

atcctagacc tgtggaaggc catcgacggg ctcccctact cccaccctcc acagccctcc      180


<210>  6100
<211>  594
<212>  DNA
<213>  Homo Sapiens

<400>  6100
ctcaatcgca caggggaccc agggcctggc ccctccatcc agaaaaccta tgacctcacc       60

cactacctgg agcaccaact ccgcagcttg gctgggacct atctgaacta cctgggcccc      120

cctttcaacg agccagactt caaccctccc cgcctggggg cagagactct gcccagggcc      180

actgttgact tggaggtgtg gcgaagcctc aatgacaaac tgcggctgac ccagaactac      240

gaggcctaca gccaccttct gtgttacttg cgtggcctca accgtcaggc tgccactgct      300

gagctgcgcc gcagcctggc ccacttctgc accagcctcc agggcctgct gggcagcatt      360

gcgggcgtca tggcagctct gggctaccca ctgccccagc cgctgcctgg gactgaaccc      420

acttggactc ctggccctgc ccacagtgac ttcctccaga agatggacga cttctggctg      480

ctgaaggagc tgcagacctg gctgtggcgc tcggccaagg acttcaaccg gctcaagaag      540

aagatgcagc ctccagcagc tgcagtcacc ctgcacctgg gggctcatgg cttc            594


<210>  6101
<211>  231
<212>  DNA
<213>  Homo Sapiens

<400>  6101
gactactggc tgtactccag cgcgcacatc tgcaacggca ccaacctgac catggacgac       60

gggcccccgc cccgccgcgc ccgcggcgac ctcacccact ctggtctgtg gcgggtgtgc      120

tgcatcgaag ggatctataa agggcactgc ttccggatca atcacttccc agaggacaat      180

gactacgacc acgacagctc ggagtacctc ctccgcatcg tgcgagcctc c               231


<210>  6102
<211>  201
<212>  DNA
<213>  Homo Sapiens

<400>  6102
ggcctaaatc aattgtactt ctattatgaa gaaacgaaag ggttaacctg caaaggcata       60

agatgtgaaa agcagaataa tgcattttca acgttatttg agacactgca gtccctgttt      120

tggtcaatat ttgggctcat caatttatat gtgaccaatg tcaaagcaca gcatgaattt      180

actgagtttg ttggtgccac c                                                201


<210>  6103
<211>  987
<212>  DNA
<213>  Homo Sapiens

<400>  6103
gcgcccgctc cgacggcgac ctcggctcca gtcaagcccg gcccggctct cagctacccg       60

caggaggagg ccaccctcaa tgagatgttc cgcgaggttg aggaactgat ggaggacacg      120

cagcacaaat tgcgcagcgc ggtggaagag atggaggcag aagaagctgc tgctaaagca      180

tcatcagaag tgaacctggc aaacttacct cccagctatc acaatgagac caacacagac      240

acgaaggttg gaaataatac catccatgtg caccgagaaa ttcacaagat aaccaacaac      300

cagactggac aaatggtctt ttcagagaca gttatcacat ctgtgggaga cgaagaaggc      360

agaaggagcc acgagtgcat catcgacgag gactgtgggc ccagcatgta ctgccagttt      420

gccagcttcc agtacacctg ccagccatgc cggggccaga ggatgctctg cacccgggac      480

agtgagtgct gtggagacca gctgtgtgtc tggggtcact gcaccaaaat ggccaccagg      540

ggcagcaatg ggaccatctg tgacaaccag agggactgcc agccggggct gtgctgtgcc      600

ttccagagag gcctgctgtt ccctgtgtgc acacccctgc ccgtggaggg cgagctttgc      660

catgaccccg ccagccggct tctggacctc atcacctggg agctagagcc tgatggagcc      720

ttggaccgat gcccttgtgc cagtggcctc ctctgccagc cccacagcca cagcctggtg      780

tatgtgtgca agccgacctt cgtggggagc cgtgaccaag atggggagat cctgctgccc      840

agagaggtcc ccgatgagta tgaagttggc agcttcatgg aggaggtgcg ccaggagctg      900

gaggacctgg agaggagcct gactgaagag atggcgctgg gggagcctgc ggctgccgcc      960

gctgcactgc tgggagggga agagatt                                          987


<210>  6104
<211>  726
<212>  DNA
<213>  Homo Sapiens

<400>  6104
ctgcccaaga gctgggactg gcgcaatgtg gatggtgtca actatgccag catcacccgg       60

aaccagcaca tcccccaata ctgcggctcc tgctgggccc acgccagcac cagcgctatg      120

gcggatcgga tcaacatcaa gaggaaggga gcgtggccct ccaccctcct gtccgtgcag      180

aacgtcatcg actgcggtaa cgctggctcc tgtgaagggg gtaatgacct gtccgtgtgg      240

gactacgccc accagcacgg catccctgac gagacctgca acaactacca ggccaaggac      300

caggagtgtg acaagtttaa ccaatgtggg acatgcaatg aattcaaaga gtgccacgcc      360

atccggaact acaccctctg gagggtggga gactacggct ccctctctgg gagggagaag      420

atgatggcag aaatctacgc aaatggtccc atcagctgtg gaataatggc aacagaaaga      480

ctggctaact acaccggagg catctatgcc gaataccagg acaccacata tataaaccat      540

gtcgtttctg tggctgggtg gggcatcagt gatgggactg agtactggat tgtccggaat      600

tcatggggtg aaccatgggg cgagagaggc tggctgagga tcgtgaccag cacctataag      660

gatgggaagg gcgccagata caaccttgcc atcgaggagc actgtacatt tggggacccc      720

atcgtt                                                                 726


<210>  6105
<211>  600
<212>  DNA
<213>  Homo Sapiens

<400>  6105
tcaaaaagct actatgatat cttaggtgtg ccaaaatcgg catcagagcg ccaaatcaag       60

aaggcctttc acaagttggc catgaagtac caccctgaca aaaataagag cccagatgct      120

gaagcaaaat tcagagagat tgcagaagca tatgaaacac tctcagatgc taatagacga      180

aaagagtatg atacacttgg acacagtgct tttactagtg gtaaaggaca aagaggtagt      240

ggaagttctt ttgagcagtc atttaacttc aattttgatg acttatttaa agactttggc      300

ttttttggtc aaaaccaaaa cactggatcc aagaagcgtt ttgaaaatca tttccagaca      360

cgccaggatg gtggttccag tagacaaagg catcatttcc aagaattttc ttttggaggt      420

ggattatttg atgacatgtt tgaagatatg gagaaaatgt tttcttttag tggttttgac      480

tctaccaatc agcatacagt acagactgaa aatagatttc atggatctag caagcactgc      540

aggactgtca ctcaacgaag aggaaatatg gttactacat acactgactg ttcaggacag      600


<210>  6106
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  6106
ggacgagatt tctataagat cttgggggtg cctcgaagtg cctctataaa ggatattaaa       60

aaggcctata ggaaactagc cctgcagctt catcccgacc ggaaccctga tgatccacaa      120

gcccaggaga aattccagga tctgggtgct gcttatgagg ttctgtcaga tagtgagaaa      180

cggaaacagt acgatactta tggtgaagaa ggattaaaag atggtcatca gagctcccat      240

ggagacattt tttcacactt ctttggggat tttggtttca tgtttggagg aacccctcgt      300

cagcaagaca gaaatattcc aagaggaagt gatattattg tagatctaga agtcactttg      360

gaagaagtat atgcaggaaa ttttgtggaa gtagttagaa acaaacctgt ggcaaggcag      420

gctcctggca aacggaagtg caattgtcgg caagagatgc ggaccaccca gctgggccct      480

gggcgcttcc aaatgaccca ggaggtggtc tgcgacgaat gccctaatgt caaactagtg      540

aatgaagaac gaacgctgga agtagaaata gagcctgggg tgagagacgg catggagtac      600

ccctttattg gagaaggtga gcctcacgtg gatggggagc ctggagattt acggttccga      660

atcaaagttg tcaagcaccc aatatttgaa aggagaggag atgatttgta cacaaatgtg      720

acaatctcat tagttgagtc actggttggc tttgagatgg atattactca cttggatggt      780

cacaaggtac atatttcccg ggataagatc accaggccag gagcgaagct atggaagaaa      840

ggggaagggc tccccaactt tgacaacaac aatatcaagg gctctttgat aatcactttt      900

gatgtggatt ttccaaaaga acagttaaca gaggaagcga gagaaggtat caaacagcta      960

ctgaaacaag ggtcagtgca gaaggtatac aatggactgc aaggatat                  1008


<210>  6107
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  6107
ctggtcctgg acttcaacaa catcaggagc tctgctgacc tgcatggggc ccggaagggc       60

tcacagtgcc tgtctgacac ggactgcaat accagaaagt tctgcctcca gccccgcgat      120

gagaagccgt tctgtgctac atgtcgtggg ttgcggagga ggtgccagcg agatgccatg      180

tgctgccctg ggacactctg tgtgaacgat gtttgtacta cgatggaaga tgcaacccca      240

atattagaaa ggcagcttga tgagcaagat ggcacacatg cagaaggaac aactgggcac      300

ccagtccagg aaaaccaacc caaaaggaag ccaagtatta agaaatcaca aggcaggaag      360

ggacaagagg gagaaagttg tctgagaact tttgactgtg gccctggact ttgctgtgct      420

cgtcattttt ggacgaaaat ttgtaagcca gtccttttgg agggacaggt ctgctccaga      480

agagggcata aagacactgc tcaagctcca gaaatcttcc agcgttgcga ctgtggccct      540

ggactactgt gtcgaagcca attgaccagc aatcggcagc atgctcgatt aagagtatgc      600

caaaaaatag aaaagcta                                                    618


<210>  6108
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  6108
aaactcaact ccatcaagtc ctctctgggc ggggagacgc ctggtcaggc cgccaatcga       60

tctgcgggca tgtaccaagg actggcattc ggcggcagta agaagggcaa aaacctgggg      120

caggcctacc cttgtagcag tgataaggag tgtgaagttg ggaggtattg ccacagtccc      180

caccaaggat catcggcctg catggtgtgt cggagaaaaa agaagcgctg ccaccgagat      240

ggcatgtgct gccccagtac ccgctgcaat aatggcatct gtatcccagt tactgaaagc      300

atcttaaccc ctcacatccc ggctctggat ggtactcagc acagagatcg aaaccacggt      360

cattactcaa accatgactt gggatggcag aatctaggaa gaccacacac taagatgtca      420

catataaaag ggcatgaagg agacccctgc ctacgatcat cagactgcat tgaagggttt      480

tgctgtgctc gtcatttctg gaccaaaatc tgcaaaccag tgctccatca gggggaagtc      540

tgtaccaaac aacgcaagaa gggttctcat gggctggaaa ttttccagcg ttgcgactgt      600

gcgaagggcc tgtcttgcaa agtatggaaa gatgccacct actcctccaa agccagactc      660

catgtgtgtc agaaaatt                                                    678


<210>  6109
<211>  1008
<212>  DNA
<213>  Homo Sapiens

<400>  6109
aactggatgt ggttgggcat tgcctccttc ggggttccag agaagctggg ctgcgccaat       60

ttgccgctga acagccgcca gaaggagctg tgcaagagga aaccgtacct gctgccgagc      120

atccgagagg gcgcccggct gggcattcag gagtgcggga gccagttcag acacgagaga      180

tggaactgca tgatcaccgc cgccgccact accgccccga tgggcgccag ccccctcttt      240

ggctacgagc tgagcagcgg caccaaagag acagcattta tttatgctgt gatggctgca      300

ggcctggtgc attctgtgac caggtcatgc agtgcaggca acatgacaga gtgttcctgt      360

gacaccacct tgcagaacgg cggctcagca agtgaaggct ggcactgggg gggctgctcc      420

gatgatgtcc agtatggcat gtggttcagc agaaagttcc tagatttccc catcggaaac      480

accacgggca aagaaaacaa agtactatta gcaatgaacc tacataacaa tgaagctgga      540

aggcaggctg tcgccaagtt gatgtcagta gactgccgct gccacggagt ttccggctcc      600

tgtgctgtga aaacatgctg gaaaaccatg tcttcttttg aaaagattgg ccatttgttg      660

aaggataaat atgaaaacag tatccagata tcagacaaaa caaagaggaa aatgcgcagg      720

agagaaaaag atcagaggaa aataccaatc cataaggatg atctgctcta tgttaataag      780

tctcccaact actgtgtaga agataagaaa ctgggaatcc cagggacaca aggcagagaa      840

tgcaaccgta catcagaggg tgcagatggc tgcaacctcc tctgctgtgg ccgaggttac      900

aacacccatg tggtcaggca cgtggagagg tgtgagtgta agttcatctg gtgctgctat      960

gtccgttgca ggaggtgtga aagcatgact gatgtccaca cttgcaag                  1008


<210>  6110
<211>  1368
<212>  DNA
<213>  Homo Sapiens

<400>  6110
gtccaagttc tgaatctgca ggcgcggctc cgggtcctgg agatgtattt cctcaatgac       60

actctggcgg ctgaggacag cccgtccttc tccttgctgc agtcagcaca ccctggagaa      120

cacctggctc agggtgcatc gaggctgcaa gtcctgcagg cccaactcac ctgggtccgc      180

gtcagccatg agcacttgct gcagcgggta gacaacttca ctcagaaccc agggatgttc      240

agaatcaaag gtgaacaagg cgccccaggt cttcaaggcc acaagggggc catgggcatg      300

cctggtgccc ctggcccgcc gggaccacct gctgagaagg gagccaaggg ggctatggga      360

cgagatggag caacaggccc ctcgggaccc caaggcccac cgggagtcaa gggagaggcg      420

ggcctccaag gaccccaggg tgctccaggg aagcaaggag ccactggcac cccaggaccc      480

caaggagaga agggcagcaa aggcgatggg ggtctcattg gcccaaaagg ggaaactgga      540

actaagggag agaaaggaga cctgggtctc ccaggaagca aaggggacag gggcatgaaa      600

ggagatgcag gggtcatggg gcctcctgga gcccagggga gtaaaggtga cttcgggagg      660

ccaggcccac caggtttggc tggttttcct ggagctaaag gagatcaagg acaacctgga      720

ctgcagggtg ttccgggccc tcctggtgca gtgggacacc caggtgccaa gggtgagcct      780

ggcagtgctg gctcccctgg gcgagcagga cttccaggga gccccgggag tccaggagcc      840

acaggcctga aaggaagcaa aggggacaca ggacttcaag gacagcaagg aagaaaagga      900

gaatcaggag ttccaggccc tgcaggtgtg aagggagaac aggggagccc agggctggca      960

ggtcccaagg gagcccctgg acaagctggc cagaagggag accagggagt gaaaggatct     1020

tctggggagc aaggagtaaa gggagaaaaa ggtgaaagag gtgaaaactc agtgtccgtc     1080

aggattgtcg gcagtagtaa ccgaggccgg gctgaagttt actacagtgg tacctggggg     1140

acaatttgcg atgacgagtg gcaaaattct gatgccattg tcttctgccg catgctgggt     1200

tactccaaag gaagggccct gtacaaagtg ggagctggca ctgggcagat ctggctggat     1260

aatgttcagt gtcggggcac ggagagtacc ctgtggagct gcaccaagaa tagctggggc     1320

catcatgact gcagccacga ggaggacgca ggcgtggagt gcagcgtc                  1368


<210>  6111
<211>  636
<212>  DNA
<213>  Homo Sapiens

<400>  6111
gcagatggaa aatatgctca gaagttgttt aatgaccttt ttgaagatta ttctaatgct       60

cttcgtccag tggaagatac agataaagtc ctgaatgtga ccctgcagat tacgctctct      120

cagattaagg atatggatga aagaaaccaa attctgactg cttatttgtg gatccgccaa      180

atctggcacg atgcctatct cacgtgggac cgagatcagt acgatggcct agactccatc      240

aggatcccca gtgacctcgt gtggaggcca gacatcgtct tatataacaa ggctgatgat      300

gaatcttcag agcctgtgaa caccaatgtg gtcctgcggt atgatgggct gatcacctgg      360

gatgcaccgg ccatcaccaa aagctcctgt gtggtggatg tcacctactt cccttttgac      420

aaccagcagt gcaacctgac ttttggttcc tggacctaca atggcaatca ggtggacata      480

ttcaacgcct tggacagcgg agatctctct gacttcattg aagatgtgga atgggaggtc      540

catggcatgc ccgctgtgaa gaatgtgatc tcctatggct gctgctctga gccttacccg      600

gatgtcacat tcaccctcct tctgaagagg aggtcc                                636


<210>  6112
<211>  1140
<212>  DNA
<213>  Homo Sapiens

<400>  6112
gagagggtgc gctactacag ggagttccac caccagactg ccctggatga gcgagaaagc       60

caccggctca tcttcccggc tgtcaccctg tgcaacatca acccactgcg ccgctcgcgc      120

ctaacgccca acgacctgca ctgggctggg tctgcgctgc tgggcctgga tcccgcagag      180

cacgccgcct tcctgcgcgc cctgggccgg ccccctgcac cgcccggctt catgcccagt      240

cccacctttg acatggcgca actctatgcc cgtgctgggc actccctgga tgacatgctg      300

ctggactgtc gcttccgtgg ccaaccttgt gggcctgaga acttcaccac gatcttcacc      360

cggatgggaa agtgctacac atttaactct ggcgctgatg gggcagagct gctcaccact      420

actaggggtg gcatgggcaa tgggctggac atcatgctgg acgtgcagca ggaggaatat      480

ctacctgtgt ggagggacaa tgaggagacc ccgtttgagg tggggatccg agtgcagatc      540

cacagccagg aggagccgcc catcatcgat cagctgggct tgggggtgtc cccgggctac      600

cagacctttg tttcttgcca gcagcagcag ctgagcttcc tgccaccgcc ctggggcgat      660

tgcagttcag catctctgaa ccccaactat gagccagagc cctctgatcc cctaggctcc      720

cccagcccca gccccagccc tccctatacc cttatggggt gtcgcctggc ctgcgaaacc      780

cgctacgtgg ctcggaagtg cggctgccga atggtgtaca tgccaggcga cgtgccagtg      840

tgcagccccc agcagtacaa gaactgtgcc cacccggcca tagatgccat gcttcgcaag      900

gactcgtgcg cctgccccaa cccgtgcgcc agcacgcgct acgccaagga gctctccatg      960

gtgcggatcc cgagccgcgc cgccgcgcgc ttcctggccc ggaagctcaa ccgcagcgag     1020

gcctacatcg cggagaacgt gctggccctg gacatcttct ttgaggccct caactatgag     1080

accgtggagc agaagaaggc ctatgagatg tcagagctgc ttggtgacat tgggggccag     1140


<210>  6113
<211>  1434
<212>  DNA
<213>  Homo Sapiens

<400>  6113
gccgagctgc gtgctccgcc agataaaatc gcgattattg gagccggaat tggtggcact       60

tcagcagcct attacctgcg gcagaaattt gggaaagatg tgaagataga cctgtttgaa      120

agagaagagg tcgggggccg cctggctacc atgatggtgc aggggcaaga atacgaggca      180

ggaggttctg tcatccatcc tttaaatctg cacatgaaac gttttgtcaa agacctgggt      240

ctctctgctg ttcaggcctc tggtggccta ctggggatat ataatggaga gactctggta      300

tttgaggaga gcaactggtt cataattaac gtgattaaat tagtttggcg ctatggattt      360

caatccctcc gtatgcacat gtgggtagag gacgtgttag acaagttcat gaggatctac      420

cgctaccagt ctcatgacta tgccttcagt agtgtcgaaa aattacttca tgctctagga      480

ggagatgact tccttggaat gcttaatcga acacttcttg aaaccttgca aaaggccggc      540

ttttctgaga agttcctcaa tgaaatgatt gctcctgtta tgagggtcaa ttatggccaa      600

agcacggaca tcaatgcctt tgtgggggcg gtgtcactgt cctgttctga ttctggcctt      660

tgggcagtag aaggtggcaa taaacttgtt tgctcagggc ttctgcaggc atccaaaagc      720

aatcttatat ctggctcagt aatgtacatc gaggagaaaa caaagaccaa gtacacagga      780

aatccaacaa agatgtatga agtggtctac caaattggaa ctgagactcg ttcagacttc      840

tatgacatcg tcttggtggc cactccgttg aatcgaaaaa tgtcgaatat tacttttctc      900

aactttgatc ctccaattga ggaattccat caatattatc aacatatagt gacaacttta      960

gttaaggggg aattgaatac atctatcttt agctctagac ccatagataa atttggcctt     1020

aatacagttt taaccactga taattcagat ttgttcatta acagtattgg gattgtgccc     1080

tctgtgagag aaaaggaaga tcctgagcca tcaacagatg gaacatatgt ttggaagatc     1140

ttttcccaag aaactcttac taaagcacaa attttaaagc tctttctgtc ctatgattat     1200

gctgtgaaga agccatggct tgcatatcct cactataagc ccccggagaa atgcccctct     1260

atcattctcc atgatcgact ttattacctc aatggcatag agtgtgcagc aagtgccatg     1320

gagatgagtg ccattgcagc ccacaacgct gcactccttg cctatcaccg ctggaacggg     1380

cacacagaca tgattgatca ggatggctta tatgagaaac ttaaaactga acta           1434


<210>  6114
<211>  2145
<212>  DNA
<213>  Homo Sapiens

<400>  6114
tttgtgtcca gtcaccgcta tgtggaaacc atgcttgtgg cagaccagtc gatggcagaa       60

ttccacggca gtggtctaaa gcattacctt ctcacgttgt tttcggtggc agccagattg      120

tacaaacacc ccagcattcg taattcagtt agcctggtgg tggtgaagat cttggtcatc      180

cacgatgaac agaaggggcc ggaagtgacc tccaatgctg ccctcactct gcggaacttt      240

tgcaactggc agaagcagca caacccaccc agtgaccggg atgcagagca ctatgacaca      300

gcaattcttt tcaccagaca ggacttgtgt gggtcccaga catgtgatac tcttgggatg      360

gctgatgttg gaactgtgtg tgatccgagc agaagctgct ccgtcataga agatgatggt      420

ttacaagctg ccttcaccac agcccatgaa ttaggccacg tgtttaacat gccacatgat      480

gatgcaaagc agtgtgccag ccttaatggt gtgaaccagg attcccacat gatggcgtca      540

atgctttcca acctggacca cagccagcct tggtctcctt gcagtgccta catgattaca      600

tcatttctgg ataatggtca tggggaatgt ttgatggaca agcctcagaa tcccatacag      660

ctcccaggcg atctccctgg cacctcgtac gatgccaacc ggcagtgcca gtttacattt      720

ggggaggact ccaaacactg ccctgatgca gccagcacat gtagcacctt gtggtgtacc      780

ggcacctctg gtggggtgct ggtgtgtcaa accaaacact tcccgtgggc ggatggcacc      840

agctgtggag aagggaaatg gtgtatcaac ggcaagtgtg tgaacaaaac cgacagaaag      900

cattttgata cgccttttca tggaagctgg ggaatgtggg ggccttgggg agactgttcg      960

agaacgtgcg gtggaggagt ccagtacacg atgagggaat gtgacaaccc agtcccaaag     1020

aatggaggga agtactgtga aggcaaacga gtgcgctaca gatcctgtaa ccttgaggac     1080

tgtccagaca ataatggaaa aacctttaga gaggaacaat gtgaagcaca caacgagttt     1140

tcaaaagctt cctttgggag tgggcctgcg gtggaatgga ttcccaagta cgctggcgtc     1200

tcaccaaagg acaggtgcaa gctcatctgc caagccaaag gcattggcta cttcttcgtt     1260

ttgcagccca aggttgtaga tggtactcca tgtagcacag attccacctc tgtctgtgtg     1320

caaggacagt gtgtaaaagc tggttgtgat cgcatcatag actccaaaaa gaagtttgat     1380

aaatgtggtg tttgcggggg aaatggatct acttgtaaaa aaatatcagg atcagttact     1440

agtgcaaaac ctggatatca tgatatcatc acaattccaa ctggagccac caacatcgaa     1500

gtgaaacagc ggaaccagag gggatccagg aacaatggca gctttcttgc catcaaagct     1560

gctgatggca catatattct taatggtgac tacactttgt ccaccttaga gcaagacatt     1620

atgtacaaag gtgttgtctt gaggtacagc ggctcctctg cggcattgga aagaattcgc     1680

agctttagcc ctctcaaaga gcccttgacc atccaggttc ttactgtggg caatgccctt     1740

cgacctaaaa ttaaatacac ctacttcgta aagaagaaga aggaatcttt caatgctatc     1800

cccacttttt cagcatgggt cattgaagag tggggcgaat gttctaagtc atgtgaattg     1860

ggttggcaga gaagactggt agaatgccga gacattaatg gacagcctgc ttccgagtgt     1920

gcaaaggaag tgaagccagc cagcaccaga ccttgtgcag accatccctg cccccagtgg     1980

cagctggggg agtggtcatc atgttctaag acctgtggga agggttacaa aaaaagaagc     2040

ttgaagtgtc tgtcccatga tggaggggtg ttatctcatg agagctgtga tcctttaaag     2100

aaacctaaac atttcataga cttttgcaca atggcagaat gcagt                     2145


<210>  6115
<211>  1401
<212>  DNA
<213>  Homo Sapiens

<400>  6115
gccccggacc ccggcttcca ggagcgcttc ttccagcagc gtctggacca cttcaacttc       60

gagcgcttcg gcaacaagac cttccctcag cgcttcctgg tgtcggacag gttctgggtc      120

cggggcgagg ggcccatctt cttctacact gggaacgagg gcgacgtgtg ggccttcgcc      180

aacaactcgg gcttcgtcgc ggagctggcg gccgagcggg gggctctact ggtcttcgcg      240

gagcaccgct actacgggaa gtcgctgccg ttcggtgcgc agtccacgca gcgcgggcac      300

acggagctgc tgacggtgga gcaggccctg gccgacttcg cagagctgct ccgcgcgcta      360

cgacgcgacc tcggggccca ggatgccccc gccatcgcct tcggtggaag ttatgggggg      420

atgctcagtg cctacctgag gatgaagtat ccccacctgg tggcgggggc gctggcggcc      480

agcgcgcccg ttctagctgt ggcaggcctc ggcgactcca accagttctt ccgggacgtc      540

acggcggact ttgagggcca gagtcccaaa tgcacccagg gtgtgcggga agcgttccga      600

cagatcaagg acttgttcct acagggagcc tacgacacgg tccgctggga gttcggcacc      660

tgccagccgc tgtcagacga gaaggacctg acccagctct tcatgttcgc ccggaatgcc      720

ttcaccgtgc tggccatgat ggactacccc taccccactg acttcctggg tcccctccct      780

gccaaccccg tcaaggtggg ctgtgatcgg ctgctgagtg aggcccagag gatcacgggg      840

ctgcgagcac tggcagggct ggtctacaac gcctcgggct ccgagcactg ctacgacatc      900

taccggctct accacagctg tgctgacccc actggctgcg gcaccggccc cgacgccagg      960

gcctgggact accaggcctg caccgagatc aacctgacct tcgccagcaa caatgtgacc     1020

gatatgttcc ccgacctgcc cttcactgac gagctccgcc agcggtactg cctggacacc     1080

tggggcgtgt ggccccggcc cgactggctg ctgaccagct tctggggggg tgatcttaga     1140

gccgccagca acatcatctt ctccaacggg aacctggacc cctgggcagg gggcgggatt     1200

cggaggaacc tgagtgcctc agtcatcgcc gtcaccatcc aggggggagc gcaccacctc     1260

gacctcagag cctcccaccc agaagatcct gcttccgtgg ttgaggcgcg gaagctggag     1320

gccaccatca tcggcgagtg ggtaaaggca gccaggcgtg agcagcagcc agctctgcgt     1380

ggggggccca gactcagcct c                                               1401


<210>  6116
<211>  216
<212>  DNA
<213>  Homo Sapiens

<400>  6116
atgaaccctc cttcggggcc aagagtcctg cccagcccaa cccaagagcc cagctgcatg       60

gccaccccag caccacccag ctggtgggac agctcccaga gcagcatctc cagcctgggc      120

cggcttccat ccatcagtcc cacagcacct gggacttggg ctgctgcctg ggtccccctc      180

cccacggttg atgttccaga ccatgcccac tatacc                                216


<210>  6117
<211>  1038
<212>  DNA
<213>  Homo Sapiens

<400>  6117
gcaggggaag ccccgggggc gctgtccact gctgatcccg ccgaccagag cgtccagtgt       60

gtccccaagg ccacctgtcc ttccagccgg cctcgccttc tctggcagac cccgaccacc      120

cagacactgc cctcgaccac catggagacc caattcccag tttctgaagg caaagtcgac      180

ccataccgct cctgtggctt ttcctacgag caggacccca ccctcaggga cccagaagcc      240

gtggctcggc ggtggccctg gatggtcagc gtgcgggcca atggcacaca catctgtgcc      300

ggcaccatca ttgcctccca gtgggtgctg actgtggccc actgcctgat ctggcgtgat      360

gttatctact cagtgagggt ggggagtccg tggattgacc agatgacgca gaccgcctcc      420

gatgtcccgg tgctccaggt catcatgcat agcaggtacc gggcccagcg gttctggtcc      480

tgggtgggcc aggccaacga catcggcctc ctcaagctca agcaggaact caagtacagc      540

aattacgtgc ggcccatctg cctgcctggc acggactatg tgttgaagga ccattcccgc      600

tgcactgtga cgggctgggg actttccaag gctgacggca tgtggcctca gttccggacc      660

attcaggaga aggaagtcat catcctgaac aacaaagagt gtgacaattt ctaccacaac      720

ttcaccaaaa tccccactct ggttcagatc atcaagtccc agatgatgtg tgcggaggac      780

acccacaggg agaagttctg ctatgagcta actggagagc ccttggtctg ctccatggag      840

ggcacgtggt acctggtggg attggtgagc tggggtgcag gctgccagaa gagcgaggcc      900

ccacccatct acctacaggt ctcctcctac caacactgga tctgggactg cctcaacggg      960

caggccctgg ccctgccagc cccatccagg accctgctcc tggcactccc actgcccctc     1020

agcctccttg ctgccctc                                                   1038


<210>  6118
<211>  924
<212>  DNA
<213>  Homo Sapiens

<400>  6118
agcagtaata acttcaacta cggggcttac cattccctgg aagctattta ccacgagatg       60

gacaacattg ccgcagactt tcctgacctg gcgaggaggg tgaagattgg acattcgttt      120

gaaaaccggc cgatgtatgt actgaagttc agcactggga aaggcgtgag gcggccggcc      180

gtttggctga atgcaggcat ccattcccga gagtggatct cccaggccac tgcaatctgg      240

acggcaagga agattgtatc tgattaccag agggatccag ctatcacctc catcttggag      300

aaaatggata ttttcttgtt gcctgtggcc aatcctgatg gatatgtgta tactcaaact      360

caaaaccgat tatggaggaa gacgcggtcc cgaaatcctg gaagctcctg cattggtgct      420

gacccaaata gaaactggaa cgctagtttt gcaggaaagg gagccagcga caacccttgc      480

tccgaagtgt accatggacc ccacgccaat tcggaagtgg aggtgaaatc agtggtagat      540

ttcatccaaa aacatgggaa tttcaagggc ttcatcgacc tgcacagcta ctcgcagctg      600

ctgatgtatc catatgggta ctcagtcaaa aaggccccag atgccgagga actcgacaag      660

gtggcgaggc ttgcggccaa agctctggct tctgtgtcgg gcactgagta ccaagtgggt      720

cccacctgca ccactgtcta tccagctagc gggagcagca tcgactgggc gtatgacaac      780

ggcatcaaat ttgcattcac atttgagttg agagataccg ggacttatgg cttcctcctg      840

ccagctaacc agatcatccc cactgcagag gagacgtggc tggggctgaa gaccatcatg      900

gagcatgtgc gggacaacct ctac                                             924


<210>  6119
<211>  303
<212>  DNA
<213>  Homo Sapiens

<400>  6119
ctcttcctgg gctgcgacac tggccctgtg gctggggtta ctgttcccta tggaaacagc       60

acagcacctg gctcagccct ggacccctac tcgccctgca ataataactg tgaatgccaa      120

accgattcct tcactccagt gtgtggggca gatggcatca cctacctgtc tgcctgcttt      180

gctggctgca acagcacgaa tctcacgggc tgtgcgtgcc tcaccaccgt ccctgctgag      240

aacgcaaccg tggttcctgg aaaatgcccc agtcctgggt gccaagaggc cttcctcact      300

ttc                                                                    303


<210>  6120
<211>  1605
<212>  DNA
<213>  Homo Sapiens

<400>  6120
cagatctact tcggggaccc ccagatcttc cagcagggtg ccgtggtgac cgatgctgcc       60

cgctgcactt cactgggcat cgaggtgctc agtaaacagg gatcttctgt ggacgcagcg      120

gtggcagtag ccttgtgttt gggtatcgtg gctccacaca gttctggcct gggcggtggg      180

ggcgtgatgc tggtacatgt catccgacga aatgagagcc acctaattga tttccgggag      240

tccgcaccag gggccctcag ggaagagacc ctgcaaagat cctgggagac caagcctggg      300

ctcttggtgg gggttcccgg aatggtgaag gggctacatg aagctcacca gctctatggc      360

aggctgccat ggtcccaagt cctggccttt gcagcagctg tggcccaaga tggcttcaac      420

gtgactcatg atctagcccg tgccctggct gaacagctgc cacccaacat gtccgagcgc      480

ttccgggaga cgttcctgcc atcgggccgc ccgccactac ctggctcgtt gctgcatcgg      540

cccgacctgg ctgaggtgct ggatgtactt ggcacctccg gcccggctgc cttctacgca      600

ggtggcaacc tcacactgga gatggtggcc gaggctcagc acgcaggggg tgtcataacc      660

gaagaggact tcagcaatta cagcgccctt gtggagaagc ctgtgtgtgg cgtgtacaga      720

ggccacctgg ttcttagtcc cccacctccg cacacgggcc ctgccctcat cagtgctctc      780

aacatcctgg agggcttcaa tctcaccagc ctggtatccc gagaacaggc tcttcactgg      840

gtggcagaga ccctgaagat tgcattagcc ctggccagca gactgggaga tcccgtctat      900

gattctacca tcactgagag catggatgac atgctcagca aggtggaggc cgcctacctc      960

cggggccata tcaatgactc ccaggcagcc cctgccccac tcctgcctgt ctatgaacta     1020

gacggagctc ccacggctgc ccaggtgctg atcatgggac ctgatgactt cattgtggcc     1080

atggttagct ccctgaacca gccctttggc agcggcctta tcaccccctc ggggatactg     1140

ctcaacagcc agatgctgga cttctcctgg cccaaccgga cagctaacca ctctgcaccc     1200

agcctggaga attcagtgca gccagggaag cggccactct ctttcctgct gcccacagtg     1260

gtccgacccg cggaggggct ctgtggaacc tacctcgctc tgggggccaa tggagctgcg     1320

cggggcctca gcggcctgac acaggttctg ctgaatgtcc tgaccttgaa ccggaacctg     1380

agtgacagcc tggcccgcgg ccgcctacac ccggacctgc agtccaacct cctgcaggtg     1440

gacagtgagt tcacagagga agagattgag ttcctggaag ccaggggtca ccacgtggag     1500

aaagtagatg tcttatcctg ggtccatggc agccgaagga ccaacaactt catcatcgct     1560

gttaaggacc ctcggagccc agatgcagct ggagccacca tcctg                     1605


<210>  6121
<211>  1221
<212>  DNA
<213>  Homo Sapiens

<400>  6121
ccagaccagc aaaaggttct actagtttct tttgatggat tccgttggga ttacttatat       60

aaagttccaa cgccccattt tcattatatt atgaaatatg gtgttcacgt gaagcaagtt      120

actaatgttt ttattacaaa aacctaccct aaccattata ctttggtaac tggcctcttt      180

gcagagaatc atgggattgt tgcaaatgat atgtttgatc ctattcggaa caaatctttc      240

tccttggatc acatgaatat ttatgattcc aagttttggg aagaagcgac accaatatgg      300

atcacaaacc agagggcagg acatactagt ggtgcagcca tgtggcccgg aacagatgta      360

aaaatacata agcgctttcc tactcattac atgccttaca atgagtcagt ttcatttgaa      420

gatagagttg ccaaaattat tgaatggttt acgtcaaaag agcccataaa tcttggtctt      480

ctctattggg aagaccctga tgacatgggc caccatttgg gacctgacag tccgctcatg      540

gggcctgtca tttcagatat tgacaagaag ttaggatatc tcatacaaat gctgaaaaag      600

gcaaagttgt ggaacactct gaacctaatc atcacaagtg atcatggaat gacgcagtgc      660

tctgaggaaa ggttaataga acttgaccag tacctggata aagaccacta taccctgatt      720

gatcaatctc cagtagcagc catcttgcca aaagaaggta aatttgatga agtctatgaa      780

gcactaactc acgctcatcc taatcttact gtttacaaaa aagaagacgt tccagaaagg      840

tggcattaca aatacaacag tcgaattcaa ccaatcatag cagtggctga tgaagggtgg      900

cacattttac agaataagtc agatgacttt ctgttaggca accacggtta cgataatgcg      960

ttagcagata tgcatccaat atttttagcc catggtcctg ccttcagaaa gaatttctca     1020

aaagaagcca tgaactccac agatttgtac ccactactat gccacctcct caatatcacc     1080

gccatgccac acaatggatc attctggaat gtccaggatc tgctcaattc agcaatgcca     1140

agggtggtcc cttatacaca gagtactata ctcctccctg gtagtgttaa accagcagaa     1200

tatgaccaag aggggtcata c                                               1221


<210>  6122
<211>  840
<212>  DNA
<213>  Homo Sapiens

<400>  6122
gcgaagatga aggtggtgga ggagcccaac gcgtttgggg tgaacaaccc gttcttgcct       60

caggccagtc gcctccaggc caagagagat ccttcacccg tgtctggacc cgtgcatctc      120

ttccgactct cgggcaagtg cttcagcctg gtggagtcca cgtacaagta tgagttctgc      180

ccgttccaca acgtgaccca gcacgagcag accttccgct ggaacgccta cagtgggatc      240

ctcggcatct ggcacgagtg ggagatcgcc aacaacacct tcacgggcat gtggatgagg      300

gacggtgacg cctgccgttc ccggagccgg cagagcaagg tggagctggc gtgtggaaaa      360

agcaaccggc tggcccatgt gtccgagccg agcacctgcg tctacgcgct gacgttcgag      420

acccccctcg tctgccaccc ccacgccttg ctagtgtacc caaccctgcc agaggccctg      480

cagcggcagt gggaccaggt agagcaggac ctggccgatg agctgatcac cccccagggc      540

catgagaagt tgctgaggac actttttgag gatgctggct acttaaagac cccagaaaat      600

gaacccaccc agctggaggg aggtcctgac agcttggggt ttgagaccct ggaaaactgc      660

aggaaggctc ataaagaact ctcaaaggag atcaaaaggc tgaaaggttt gctcacccag      720

cacggcatcc cctacacgag gcccacagaa acttccaact tggagcactt gggccacgag      780

acgcccagag ccaagtctcc agagcagctg cggggtgacc caggactgcg tgggagtttg      840


<210>  6123
<211>  618
<212>  DNA
<213>  Homo Sapiens

<400>  6123
gaacaagaag tggaaaatct ctcaggcctt tccactaacc ctgaaaaaga tatatttgtg       60

gtgcgggaaa atgggacgac gtgtctcatg gcagagtttg cagccaaatt tattgtacct      120

tatgatgtgt gggccagcaa ctacgtagat ctgatcacag aacaggccga tatcgcattg      180

acccggggag ctgaggtgaa gggccgctgt ggccacagcc agtcggagct gcaagtgttc      240

tgggtggatc gcgcatatgc actcaaaatg ctctttgtaa aggaaagcca caacatgtcc      300

aagggacctg aggcgacttg gaggctgagc aaagtgcagt ttgtctacga ctcctcggag      360

aaaacccact tcaaagacgc agtcagtgct gggaagcaca cagccaactc gcaccacctc      420

tctgccttgg tcacccccgc tgggaagtcc tatgagtgtc aagctcaaca aaccatttca      480

ctggcctcta gtgatccgca gaagacggtc accatgatcc tgtctgcggt ccacatccaa      540

ccttttgaca ttatctcaga ttttgtcttc agtgaagagc ataaatgccc agtggatgag      600

cgggagcaac tggaagaa                                                    618


<210>  6124
<211>  1428
<212>  DNA
<213>  Homo Sapiens

<400>  6124
atgtggaccg gatataagat cttaatcttc tcttatctta ctacagaaat ctggatggag       60

aagcggtatt tatctcaaag agaagtggac ctagaggctt atttcactag gaatcacacc      120

gttttgcaag gtactcgatt caaaagagcc attttccaag ggcaatactg tagaaatttt      180

ggctgttgtg aagacagaga tgatggctgt gtcactgagt tctatgcggc gaatgcgttg      240

tgctactgtg ataaattctg tgacagagaa aattctgatt gctgtcctga ctacaagtcc      300

ttttgccgtg aagagaaaga atggcctcct cacacacagc cttggtatcc agaaggttgc      360

ttcaaagatg gtcaacatta tgaagaggga tcagtaatta aagaaaactg caactcctgc      420

acatgctcag gacagcaatg gaaatgttcc cagcatgtat gccttgttcg ttcagaatta      480

attgaacagg tcaataaagg agactatgga tggacagcac agaattacag ccaattttgg      540

ggaatgactt tagaagatgg ttttaaattt cgccttggca ctttgccacc tagtctcatg      600

ctcctgagca tgaatgaaat gacagcttct ttacctgcaa caactgatct tccagagttt      660

tttgttgctt cttataaatg gcctggatgg actcatggcc cattggatca aaaaaattgt      720

gctgcatcct gggcattttc cactgcaagt gtggctgctg accgaatagc aattcagtct      780

aagggtcgat acacggccaa tctatcccct cagaatttga tctcttgctg tgccaagaac      840

cgtcatggat gcaatagtgg aagcatcgat agggcttggt ggtacctgag aaaacgtgga      900

ctggtatccc acgcatgcta cccacttttc aaagaccaaa atgctaccaa caatggatgt      960

gccatggcaa gcaggtctga tgggcgagga aaacggcatg ccacgaagcc atgtcccaac     1020

aacgtagaaa aatctaacag gatctatcaa tgttctcctc catacagagt ctcttccaac     1080

gaaactgaga taatgaaaga aatcatgcaa aatggaccag ttcaagccat aatgcaagtc     1140

catgaagatt tcttccatta taagacaggg atatacagac atgttaccag cacaaataaa     1200

gaatcagaaa aatatcgaaa gcttcagaca catgcagtca aactcactgg atggggcaca     1260

ctgagaggag cacaagggca gaaagaaaaa ttttggattg ctgccaattc ctggggaaag     1320

tcatggggag agaatggcta tttcaggatt cttcgaggag taaatgagtc cgacattgaa     1380

aagttgatta tcgcagcttg gggccaactg acgagttctg atgaacca                  1428


<210>  6125
<211>  729
<212>  DNA
<213>  Homo Sapiens

<400>  6125
gcgccgtccg cccgcgatcc cttcgccccc cagctcgggg acacgcagaa ctgccagctg       60

cggtgccgcg accgcgacct cggcccgcag ccctcgcagg cggggctgga gggcgcctcc      120

gagtctccct atgacagagc cgttctgatc agcgcttgcg agcgtggctg ccgcctcttc      180

tccatctgcc gatttgtggc cagaagctcc aagcccaatg ccacccaaac tgagtgtgaa      240

gcagcctgcg tggaagccta tgtgaaggag gcagagcagc aggcctgtag ccacggctgc      300

tggagccagc ccgcggagcc tgagccggag cagaagagaa aggtcctgga ggctccaagt      360

ggggccctct ccctcttgga cttgttttcc accctctgca atgacctcgt caactcagcc      420

cagggatttg tctcctccac ctggacatac tacttgcaga ctgacaatgg gaaagtggtg      480

gtgtttcaga ctcagcccat agtggagagc ctcggcttcc aggggggccg tctgcagcgc      540

gtggaggtga cctggcgagg ctcccaccct gaagccctgg aggtgcacgt ggaccctgta      600

ggccccctgg acaaggtgag gaaggccaag atccgagtca agaccagcag caaggccaag      660

gtggagtctg aagagccaca ggacaatgac ttcctcagtt gcatgtcccg gcgctcgggt      720

ctgcctcgc                                                              729


<210>  6126
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  6126
ttggccccca gtcctcagtc gccagagacc ccagcccctc agaaccagac cagcagggta       60

gtgcaggctc ccaaggagga agaggaagat gagcaggagg ccagcgagga gaaggccagt      120

gaggaagaga aagcctggct gatggccagc aggcagcagc ttgccaagga gacttcaaac      180

ttcggattca gcctgctgcg aaagatctcc atgaggcacg atggcaacat ggtcttctct      240

ccatttggca tgtccttggc catgacaggc ttgatgctgg gggccacagg gccgactgaa      300

acccagatca agagagggct ccacttgcag gccctgaagc ccaccaagcc cgggctcctg      360

ccttccctct ttaagggact cagagagacc ctctcccgca acctggaact gggcctcaca      420

caggggagtt ttgccttcat ccacaaggat tttgatgtca aagagacttt cttcaattta      480

tccaagaggt attttgatac agagtgcgtg cctatgaatt ttcgcaatgc ctcacaggcc      540

aaaaggctca tgaatcatta cattaacaaa gagactcggg ggaaaattcc caaactgttt      600

gatgagatta atcctgaaac caaattaatt cttgtggatt acatcttgtt caaagggaaa      660

tggttgaccc catttgaccc tgtcttcacc gaagtcgaca ctttccacct ggacaagtac      720

aagaccatta aggtgcccat gatgtacggt gcaggcaagt ttgcctccac ctttgacaag      780

aattttcgtt gtcatgtcct caaactgccc taccaaggaa atgccaccat gctggtggtc      840

ctcatggaga aaatgggtga ccacctcgcc cttgaagact acctgaccac agacttggtg      900

gagacatggc tcagaaacat gaaaaccaga aacatggaag ttttctttcc gaagttcaag      960

ctagatcaga agtatgagat gcatgagctg cttaggcaga tgggaatcag aagaatcttc     1020

tcaccctttg ctgaccttag tgaactctca gctactggaa gaaatctcca agtatccagg     1080

gttttacaaa gaacagtgat tgaagttgat gaaaggggca ctgaggcagt ggcaggaatc     1140

ttgtcagaaa ttactgctta ttccatgcct cctgtcatca aagtggaccg gccatttcat     1200

ttcatgatct atgaagaaac ctctggaatg cttctgtttc tgggcagggt ggtgaatccg     1260

actctccta                                                             1269


<210>  6127
<211>  636
<212>  DNA
<213>  Homo Sapiens

<400>  6127
gctcctatcc atgatgctga cgcccaagag agctccttgg gtctcacagg cctccagagc       60

ctactccaag gcttcagccg acttttcctg aaaggtaacc tgcttcgggg catagacagc      120

ttattctctg cccccatgga cttccggggc ctccctggga actaccacaa agaggagaac      180

caggagcacc agctggggaa caacaccctc tccagccacc tccagatcga caagatgacc      240

gacaacaaga caggagaggt gctgatctcc gagaatgtgg tggcatccat tcaaccagcg      300

gaggggagct tcgagggtga tttgaaggta cccaggatgg aggagaagga ggccctggta      360

cccatccaga aggccacgga cagcttccac acagaactcc atccccgggt ggccttctgg      420

atcattaagc tgccacggcg gaggtcccac caggatgccc tggagggcgg ccactggctc      480

agcgagaagc gacaccgcct gcaggccatc cgggatggac tccgcaaggg gacccacaag      540

gacgtcctag aagaggggac cgagagctcc tcccactcca ggctgtcccc ccgaaagacc      600

cacttactgt acatcctcag gccctctcgg cagctg                                636


<210>  6128
<211>  309
<212>  DNA
<213>  Homo Sapiens

<400>  6128
gtcctggccc agctggatgc actgctggtc ttcccaggcc aagtggctca actctcctgc       60

acgctcagcc cccagcacgt caccatcagg gactacggtg tgtcctggta ccagcagcgg      120

gcaggcagtg cccctcgata tctcctctac taccgctcgg aggaggatca ccaccggcct      180

gctgacatcc ccgatcgatt ctcggcagcc aaggatgagg cccacaatgc ctgtgtcctc      240

accattagtc ccgtgcagcc tgaagacgac gcggattact actgctctgt tggctacggc      300

tttagtccc                                                              309


<210>  6129
<211>  705
<212>  DNA
<213>  Homo Sapiens

<400>  6129
catggctggg cagacacccg tgccatcggg gccgaggaat gtcgccccaa ctcccagcct       60

tggcaggccg gcctcttcca ccttactcgg ctcttctgtg gggcgaccct catcagtgac      120

cgctggctgc tcacagctgc ccactgccgc aagccgtatc tgtgggtccg ccttggagag      180

caccacctct ggaaatggga gggtccggag cagctgttcc gggttacgga cttcttcccc      240

caccctggct tcaacaagga cctcagcgcc aatgaccaca atgatgacat catgctgatc      300

cgcctgccca ggcaggcacg tctgagtcct gctgtgcagc ccctcaacct cagccagacc      360

tgtgtctccc caggcatgca gtgtctcatc tcaggctggg gggccgtgtc cagccccaag      420

gcgctgtttc cagtcacact gcagtgtgcc aacatcagca tcctggagaa caaactctgt      480

cactgggcat accctggaca catctcggac agcatgctct gtgcgggcct gtgggagggg      540

ggccgaggtt cctgccaggg tgactctggg ggccccctgg tttgcaatgg aaccttggca      600

ggcgtggtgt ctgggggtgc tgagccctgc tccagacccc ggcgccccgc agtctacacc      660

agcgtatgcc actaccttga ctggatccaa gaaatcatgg agaac                      705


<210>  6130
<211>  783
<212>  DNA
<213>  Homo Sapiens

<400>  6130
ggaggtgtct cccaggagtc ttccaaggtt ctcaacacca atgggaccag tgggtttctc       60

ccaggtggct acacctgctt cccccactct cagccctggc aggctgccct actagtgcaa      120

gggcggctac tctgtggggg agtcctggtc caccccaaat gggtcctcac tgccgcacac      180

tgtctaaagg aggggctcaa agtttaccta ggcaagcacg ccctagggcg tgtggaagct      240

ggtgagcagg tgagggaagt tgtccactct atcccccacc ctgaataccg gagaagcccc      300

acccacctga accacgacca tgacatcatg cttctggagc tgcagtcccc ggtccagctc      360

acaggctaca tccaaaccct gcccctttcc cacaacaacc gcctaacccc tggcaccacc      420

tgtcgggtgt ctggctgggg caccaccacc agcccccagg tgaattaccc caaaactcta      480

caatgtgcca acatccaact tcgctcagat gaggagtgtc gtcaagtcta cccaggaaag      540

atcactgaca acatgttgtg tgccggcaca aaagagggtg gcaaagactc ctgtgagggt      600

gactctgggg gccccctggt ctgtaacaga acactgtatg gcatcgtctc ctggggagac      660

ttcccatgtg ggcaacctga ccggcctggt gtctacaccc gtgtctcaag atacgtcctg      720

tggatccgtg aaacaatccg aaaatatgaa acccagcagc aaaaatggtt gaagggccca      780

caa                                                                    783


<210>  6131
<211>  2889
<212>  DNA
<213>  Homo Sapiens

<400>  6131
agcctgcgct tcgacgagtg cggggcgagt gccacgccag gcgccgacgg tggcccctca       60

ggctttccgg agcgcggcgg caacgggagc ctccctggat cggcccggcg caaccaccac      120

gcaggcgggg actcctggca gcccgaggcg ggtggggtgg ccagtccggg gaccacgtcg      180

gcccagccgc cgtcggagga ggagcgggag ccgtgggagc cgtggacgca gctgcgcctg      240

tcgggccacc tgaagccgct gcactacaat ctgatgctca ccgccttcat ggagaacttc      300

accttctccg gggaggtcaa cgtggagatc gcgtgccgga acgccacccg ctacgtagtg      360

ctgcacgctt cccgagtggc ggtggagaaa gtgcagctgg ccgaggaccg ggcgttcggg      420

gctgtccctg tagccggttt tttcctctac ccgcaaaccc aggtcttagt ggtggtgctg      480

aataggacac tggacgcgca gaggaattac aatctgaaga ttatctacaa cgcgctcatc      540

gagaatgagc tcctgggctt cttccgcagc tcctatgtgc tccacgggga gagaagattc      600

cttggtgtta ctcagttttc gcctacacat gccagaaagg catttccttg ttttgatgag      660

ccaatctaca aggctacttt caaaatcagc atcaagcatc aagcaaccta tttatcttta      720

tctaatatgc cagtggaaac ttccgtgttt gaggaagatg gatgggttac ggatcacttt      780

tcacagaccc ctctcatgtc cacatattat ttagcctggg caatttgcaa cttcacatac      840

agagaaacta ccaccaagag tggggttgta gtacgattat atgcaagacc tgatgctatc      900

agaagaggat ccggggacta tgctctccat ataacaaaga gattaataga attttatgaa      960

gactacttta aagtgcccta ttccttgcca aaactagatc ttttagctgt gcctaagcat     1020

ccgtatgctg ctatggagaa ctggggacta agtatttttg tggaacaaag aatactgctg     1080

gatcccagtg tttcatctat ttcttatttg ctggatgtca ccatggtcat tgttcatgag     1140

atatgtcacc agtggtttgg tgaccttgtg acgcctgtgt ggtgggaaga cgtgtggctg     1200

aaggaagggt ttgctcacta ctttgaattt gttggtacag actacctcta tcctggctgg     1260

aacatggaaa agcagaggtt tctgaccgat gttctgcatg aagtgatgct gctggacggt     1320

ttggccagtt cccatccagt atcacaggaa gtgctgcagg caacagatat tgacagggtg     1380

tttgactgga tcgcatataa aaagggtgct gctttaataa gaatgctggc taattttatg     1440

ggccattcag ttttccagag gggtttgcaa gattatttaa ccattcataa gtatggtaat     1500

gcagccagaa atgatctctg gaatacatta tcggaggctt taaaaagaaa tgggaaatat     1560

gtaaatatac aagaagtaat ggatcagtgg acactccaga tgggttatcc tgttatcacc     1620

atcttgggaa acacaacagc agaaaataga ataataatta cccaacagca ttttatctat     1680

gatatcagtg ctaaaactaa agcacttaaa cttcagaata acagttacct gtggcagatt     1740

ccattaacta ttgtggtagg aaatagaagc catgtgtctt cagaagcaat tatttgggtg     1800

tctaacaaat cagagcacca cagaataact tatttggaca aaggaagctg gctgctgggg     1860

aacatcaatc aaactggcta ttttagagtc aactatgacc taaggaactg gagattatta     1920

attgatcaat taatccggaa tcatgaggtt ctttctgtca gtaaccgagc gggcttgatc     1980

gatgatgcct tcagcctagc cagggctggc tatttgcctc agaatattcc tctggagatt     2040

atcagatacc tgtctgagga gaaggatttt cttccttggc atgctgccag ccgagctctt     2100

tatcctctag ataaattact ggaccgcatg gaaaactaca acattttcaa tgaatatatt     2160

ttaaagcaag ttgcaacaac atatatcaag cttgggtggc cgaaaaataa ttttaatgga     2220

tctcttgttc aagcatccta ccaacatgaa gaactacgta gagaagttat aatgctggcc     2280

tgcagttttg gcaacaagca ctgtcaccaa caggcatcaa cacttatttc agattggatt     2340

tccagcaaca ggaacagaat accactaaat gttagagaca tcgtatactg tacaggagtg     2400

tcactactgg atgaggatgt ctgggaattc atatggatga aattccattc caccacagca     2460

gtttctgaga agaaaatatt attggaagcc ttaacttgca gtgatgacag gaatttatta     2520

aacaggcttc taaatctgtc actgaattct gaggtggtgc tggatcaaga tgcaattgat     2580

gtcataatcc atgtagctcg aaatccacat ggtcgagacc ttgcctggaa gtttttcagg     2640

gataaatgga agatattaaa taccaggtat ggagaagcat tgtttatgaa ttccaaactc     2700

atcagtggtg tcacagaatt tcttaatact gaaggtgaac tcaaagagct caagaacttc     2760

atgaaaaact atgatggggt agctgctgct tctttctcac gagctgtgga aactgtcgaa     2820

gccaatgtgc gctggaaaat gctttaccaa gacgagcttt tccaatggtt aggaaaagct     2880

ctaagacac                                                             2889


<210>  6132
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  6132
acgaggggca tcaagcacag aatcaagtgg aaccggaagg ccctgcccag cactgcccag       60

atcactgagg cccaggtggc tgagaaccgc ccgggagcct tcatcaagca aggccgcaag      120

ctcgacattg acttcggagc cgagggcaac aggtactacg aggccaacta ctggcagttc      180

cccgatggca tccactacaa cggctgctct gaggctaatg tgaccaagga ggcatttgtc      240

accggctgca tcaatgccac ccaggcggcg aaccaggggg agttccagaa gccagacaac      300

aagctccacc agcaggtgct ctggcggctg gtccaggagc tctgctccct caagcattgc      360

gagttttggt tggagagggg c                                                381


<210>  6133
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  6133
cagtccccag agagacctgt tttcacatgt ggtggcattc ttactggaga gtctggattt       60

attggcagtg aaggttttcc tggagtgtac cctccaaata gcaaatgtac ttggaaaatc      120

acagttcccg aaggaaaagt agtcgttctc aatttccgat tcatagacct cgagagtgac      180

aacctgtgcc gctatgactt tgtggatgtg tacaatggcc atgccaatgg ccagcgcatt      240

ggccgcttct gtggcacttt ccggcctgga gcccttgtgt ccagtggcaa caagatgatg      300

gtgcagatga tttctgatgc caacacagct ggcaatggct tcatggccat gttctccgct      360

gctgaaccaa acgaaagagg ggatcagtat tgtggaggac tccttgacag accttccggc      420

tcttttaaaa cccccaactg gccagaccgg gattaccctg caggagtcac ttgtgtgtgg      480

cacattgtag ccccaaagaa tcagcttata gaattaaagt ttgagaagtt tgatgtggag      540

cgagataact actgccgata tgattatgtg gctgtgttta atggcgggga agtcaacgat      600

gctagaagaa ttggaaagta ttgtggtgat agtccacctg cgccaattgt gtctgagaga      660

aatgaacttc ttattcagtt tttatcagac ttaagtttaa ctgcagatgg gtttattggt      720

cactacatat tcaggccaaa aaaactgcct acaactacag aacagcctgt caccaccaca      780

ttccctgtaa ccacgggttt aaaacccacc gtggccttgt gtcaacaaaa gtgtagacgg      840

acggggactc tggagggcaa ttattgttca agtgactttg tattagccgg cactgttatc      900

acaaccatca ctcgcgatgg gagtttgcac gccacagtct cgatcatcaa catctacaaa      960

gagggaaatt tggcgattca gcaggcgggc aagaacatga gtgccaggct gactgtcgtc     1020

tgcaagcagt gccctctcct cagaagaggt ctaaattaca ttattatggg ccaagtaggt     1080

gaagatgggc gaggcaaaat catgccaaac agctttatca tgatgttcaa gaccaagaat     1140

cagaagctcc tggatgcctt aaaaaataag caatgt                               1176


<210>  6134
<211>  2640
<212>  DNA
<213>  Homo Sapiens

<400>  6134
tacatcaccg acgagaaccc agaagttatg attcccttca ccaatgccaa ctacgacagc       60

catcccatgc tgtacttctc cagggcagaa gtggcggagc tgcagctcag ggctgccagc      120

tcgcacgagc acattgcagc ccgcctcacg gaggctgtgc acacgatgct gtccagcccc      180

ttggaatacc tccctccctg ggatcccaag gactacagtg cccgctggaa tgaaattttt      240

ggaaacaact tgggtgcctt ggcaatgttc tgtgtgctgt atcctgagaa cattgaagcc      300

cgagacatgg ccaaagacta catggagagg atggcagcgc agcctagttg gttggtgaaa      360

gatgctcctt gggatgaggt cccgcttgct cactccctgg ttggttttgc cactgcttat      420

gacttcttgt acaactacct gagcaagaca caacaggaga agtttcttga agtgattgcc      480

aatgcctcag ggtatatgta tgaaacttca tacaggagag gatggggatt tcaatacctg      540

cacaatcatc agcccaccaa ctgtatggct ttgctcacgg gaagcctagt cctgatgaat      600

caaggatatc ttcaagaagc ctacttatgg accaaacaag ttctgaccat catggagaaa      660

tctctggtct tgctcaggga ggtgacggat ggctccctct atgaaggagt tgcgtatggc      720

agctacacca ctagatcact cttccaatac atgtttctcg tccagaggca cttcaacatc      780

aaccactttg gccatccgtg gcttaaacaa cactttgcat ttatgtatag aaccatcctg      840

ccagggtttc aaaggactgt ggctattgcg gactcaaatt acaactggtt ttatggtcca      900

gaaagccaat tagtgttcct tgataaattt gtcatgcgta atggcagtgg taactggcta      960

gctgaccaaa tcagaaggaa ccgtgtggtg gaaggtccag gaacaccatc caaagggcag     1020

cgctggtgca ctctgcacac agaatttctc tggtatgatg gcagcttgaa atcggttcct     1080

cctccagact ttggcacccc tacactgcat tattttgaag actggggtgt cgtgacttat     1140

ggaagtgcac tacctgcaga aatcaataga tctttccttt ccttcaagtc tggaaaactg     1200

gggggacgtg caatatatga cattgtccac agaaacaaat acaaagattg gatcaaagga     1260

tggagaaatt ttaatgcagg gcatgaacat cctgatcaaa actcatttac ttttgctccc     1320

aatggtgtgc ctttcattac tgaggctctg tacgggccaa agtacacctt cttcaacaat     1380

gttttgatgt tttccccagc tgtgtcaaag agctgctttt ctccctgggt gggtcaggtc     1440

acagaagact gctcatcaaa atggtctaaa tacaagcatg acctggcagc tagttgtcag     1500

gggagggtgg ttgcagcaga ggagaaaaat ggggtggttt tcatccgagg agaaggtgtg     1560

ggagcttata acccccagct caacctgaag aatgttcaga ggaatctcat cctcctacat     1620

ccacagctgc ttctccttgt agaccaaata cacctgggag aggagagtcc cttggagaca     1680

gcagcgagct tcttccataa tgtggatgtt ccttttgagg agactgtggt agatggtgtc     1740

catggggctt tcatcaggca gagagatggt ctctataaaa tgtactggat ggacgatact     1800

ggctacagcg agaaagcaac ctttgcctca gtgacatatc ctcggggcta tccctacaac     1860

gggacaaact atgtgaatgt caccatgcac ctccgaagtc ccatcaccag ggcagcttac     1920

ctcttcatag ggccatctat agatgttcag agcttcactg tccacggaga ctctcagcaa     1980

ctggatgtgt tcatagccac cagcaaacat gcctacgcca catacctgtg gacaggtgag     2040

gccacaggac agtctgcctt tgcacaggtc attgctgatc gtcacaaaat tctgtttgac     2100

cggaattcag ccatcaagag cagcattgtc cctgaggtga aggactatgc tgctattgtg     2160

gaacagaact tgcagcattt taaaccagtg tttcagctgc tggagaagca gatactgtcc     2220

cgagtccgga acacagctag ctttaggaag actgctgaac gcctgctgag attttcagat     2280

aagagacaga ctgaggaggc cattgacagg atttttgcca tatcacagca acagcagcag     2340

caaagcaagt caaagaaaaa ccgaagggca ggcaaacgct ataaatttgt ggatgctgtc     2400

cctgatattt ttgcacagat tgaagtcaat gagaaaaaga ttagacagaa agctcagatt     2460

ttggcacaga aagaactacc catagatgaa gatgaagaaa tgaaagacct tttagatttt     2520

gcagatgtaa catacgagaa acataaaaat gggggcttga ttaaaggccg gtttggacag     2580

gcacggatgg tgacaactac acacagcagg gccccatcac tgtctgcttc ctataccagg     2640


<210>  6135
<211>  1149
<212>  DNA
<213>  Homo Sapiens

<400>  6135
cattatgtga gatataatca aaagaagacc tacaattact atagcacatt gtcatttaca       60

actgacaaac tatatgctga gtttggcaga gaggcttcta acaattttac agaaatgagc      120

cagagacttg aatcaatggt gaaaaatgca ttttataaat ctccattaag ggaagaattt      180

gtcaagtctc aggttatcaa gttcagtcaa cagaagcatg gagtgttggc tcatatgctg      240

ttgatttgta gatttcactc tactgaggat cctgaaactg tagataaaat tgttcaactt      300

gttttacatg aaaagctgca agatgctgta ggacccccta aagtagatcc tcactcagtt      360

aaaattaaaa aaatcaacaa gacagaaaca gacagctatc taaaccattg ctgcggaaca      420

cgaagaagta aaactctagg tcagagtctc aggatcgttg gtgggacaga agtagaagag      480

ggtgaatggc cctggcaggc tagcctgcag tgggatggga gtcatcgctg tggagcaacc      540

ttaattaatg ccacatggct tgtgagtgct gctcactgtt ttacaacata taagaaccct      600

gccagatgga ctgcttcctt tggagtaaca ataaaacctt cgaaaatgaa acggggtctc      660

cggagaataa ttgtccatga aaaatacaaa cacccatcac atgactatga tatttctctt      720

gcagagcttt ctagccctgt tccctacaca aatgcagtac atagagtttg tctccctgat      780

gcatcctatg agtttcaacc aggtgatgtg atgtttgtga caggatttgg agcactgaaa      840

aatgatggtt acagtcaaaa tcatcttcga caagcacagg tgactctcat agacgctaca      900

acttgcaatg aacctcaagc ttacaatgac gccataactc ctagaatgtt atgtgctggc      960

tccttagaag gaaaaacaga tgcatgccag ggtgactctg gaggaccact ggttagttca     1020

gatgctagag atatctggta ccttgctgga atagtgagct ggggagatga atgtgcgaaa     1080

cccaacaagc ctggtgttta tactagagtt acggccttgc gggactggat tacttcaaaa     1140

actggtatc                                                             1149


<210>  6136
<211>  210
<212>  DNA
<213>  Homo Sapiens

<400>  6136
ggactgaacc agctttactt ctattatgaa accagagcta tcgatgagcc taacaactgc       60

aaggggatcc gatgtgagaa acagaacaat gccttctcca cgctctttga gactcttcag      120

tcactcttct ggtctgtatt tggcctttta aatctatatg tcaccaatgt gaaagccaga      180

cacgaattca ccgagtttgt aggagctacc                                       210


<210>  6137
<211>  558
<212>  DNA
<213>  Homo Sapiens

<400>  6137
ttcggggacg aggaagagcg gcgctgcgac cccatccgca tctccatgtg ccagaacctc       60

ggctacaacg tgaccaagat gcccaacctg gttgggcacg agctgcagac ggacgccgag      120

ctgcagctga caactttcac accgctcatc cagtacggct gctccagcca gctgcagttc      180

ttcctttgtt ctgtttatgt gccaatgtgc acagagaaga tcaacatccc cattggccca      240

tgcggcggca tgtgtctttc agtcaagaga cgctgtgaac ccgtcctgaa ggaatttgga      300

tttgcctggc cagagagtct gaactgcagc aaattcccac cacagaacga ccacaaccac      360

atgtgcatgg aagggccagg tgatgaagag gtgcccttac ctcacaaaac ccccatccag      420

cctggggaag agtgtcactc tgtgggaacc aattctgatc agtacatctg ggtgaaaagg      480

agcctgaact gtgtgctcaa gtgtggctat gatgctggct tatacagccg ctcagccaag      540

gagttcactg atatctgg                                                    558


<210>  6138
<211>  615
<212>  DNA
<213>  Homo Sapiens

<400>  6138
atcagctcca tggacatgga gcgcccgggc gacggcaaat gccagcccat cgagatcccg       60

atgtgcaagg acatcggcta caacatgact cgtatgccca acctgatggg ccacgagaac      120

cagcgcgagg cagccatcca gttgcacgag ttcgcgccgc tggtggagta cggctgccac      180

ggccacctcc gcttcttcct gtgctcgctg tacgcgccga tgtgcaccga gcaggtctct      240

acccccatcc ccgcctgccg ggtcatgtgc gagcaggccc ggctcaagtg ctccccgatt      300

atggagcagt tcaacttcaa gtggcccgac tccctggact gccggaaact ccccaacaag      360

aacgacccca actacctgtg catggaggcg cccaacaacg gctcggacga gcccacccgg      420

ggctcgggcc tgttcccgcc gctgttccgg ccgcagcggc cccacagcgc gcaggagcac      480

ccgctgaagg acgggggccc cgggcgcggc ggctgcgaca acccgggcaa gttccaccac      540

gtggagaaga gcgcgtcgtg cgcgccgctc tgcacgcccg gcgtggacgt gtactggagc      600

cgcgaggaca agcgc                                                       615


<210>  6139
<211>  825
<212>  DNA
<213>  Homo Sapiens

<400>  6139
gcagatgggg gtcaacactg gacgtatgag ggcccacatg gtcaggacca ttggccagcc       60

tcttaccctg agtgtggaaa caatgcccag tcgcccatcg atattcagac agacagtgtg      120

acatttgacc ctgatttgcc tgctctgcag ccccacggat atgaccagcc tggcaccgag      180

cctttggacc tgcacaacaa tggccacaca gtgcaactct ctctgccctc taccctgtat      240

ctgggtggac ttccccgaaa atatgtagct gcccagctcc acctgcactg gggtcagaaa      300

ggatccccag gggggtcaga acaccagatc aacagtgaag ccacatttgc agagctccac      360

attgtacatt atgactctga ttcctatgac agcttgagtg aggctgctga gaggcctcag      420

ggcctggctg tcctgggcat cctaattgag gtgggtgaga ctaagaatat agcttatgaa      480

cacattctga gtcacttgca tgaagtcagg cataaagatc agaagacctc agtgcctccc      540

ttcaacctaa gagagctgct ccccaaacag ctggggcagt acttccgcta caatggctcg      600

ctcacaactc ccccttgcta ccagagtgtg ctctggacag ttttttatag aaggtcccag      660

atttcaatgg aacagctgga aaagcttcag gggacattgt tctccacaga agaggagccc      720

tctaagcttc tggtacagaa ctaccgagcc cttcagcctc tcaatcagcg catggtcttt      780

gcttctttca tccaagcagg atcctcgtat accacaggtg aaatg                      825


<210>  6140
<211>  561
<212>  DNA
<213>  Homo Sapiens

<400>  6140
gccccgcgcc cgtgccaggc gccgcagcag tgggaggggc gccaggttat gtaccagcaa       60

agtagcgggc gcaacagccg cgccctgctc tcctacgacg ggctcaacca gcgcgtgcgg      120

gtgctggacg agaggaaggc gctgatcccc tgcaagagat tatttgaata tattttgctg      180

tataaggatg gagtgatgtt tcagattgac caagccacca agcagtgctc aaagatgacc      240

ctgacacagc cctgggatcc tcttgacatt cctcaaaact ccacctttga agaccagtac      300

tccattgggg ggcctcagga gcagatcacc gtccaggagt ggtcggacag aaagtcagct      360

agatcctatg aaacctggat tggcatctat acagtcaagg attgctatcc tgtccaggaa      420

acctttacca taaactacag tgtgatattg tctacgcggt tttttgacat ccagctgggt      480

attaaagacc cctcggtgtt tacccctcca agcacgtgcc agatggccca actggagaag      540

atgagcgaag actgctcctg g                                                561


<210>  6141
<211>  825
<212>  DNA
<213>  Homo Sapiens

<400>  6141
gcccccgcgc cccaccgcgc gtcctacaag ccggtcatcg tggtgcatgg gctcttcgac       60

agctcgtaca gcttccgcca cctgctggaa tacatcaatg agacacaccc cgggactgtg      120

gtgacagtgc tcgatctctt cgatgggaga gagagcttgc gacccctgtg ggaacaggtg      180

caagggttcc gagaggctgt ggtccccatc atggcaaagg cccctcaagg ggtgcatctc      240

atctgctact cgcagggggg ccttgtgtgc cgggctctgc tttctgtcat ggatgatcac      300

aacgtggatt ctttcatctc cctctcctct ccacagatgg gacagtatgg agacacggac      360

tacttgaagt ggctgttccc cacctccatg cggtctaacc tctatcggat ctgctatagc      420

ccctggggcc aggaattctc catctgcaac tactggcatg atccccacca cgatgacttg      480

tacctcaatg ccagcagctt cctggccctg atcaatgggg aaagagacca tcccaatgcc      540

acagtatggc ggaagaactt tctgcgtgtg ggccacctgg tgctgattgg gggccctgat      600

gatggtgtta ttactccctg gcagtccagc ttctttggtt tctatgatgc aaatgagacc      660

gtcctggaga tggaggagca actggtttat ctgcgggatt cttttgggtt gaagactcta      720

ttggcccggg gggccatagt gaggtgtcca atggccggta tctcccacac agcctggcac      780

tccaaccgta ccctttatga gacctgcatt gaaccttggc tctcc                      825


<210>  6142
<211>  423
<212>  DNA
<213>  Homo Sapiens

<400>  6142
gggcagacac cgcgccctgc cgagcggggg cccccagtgc ggcttttcac cgaggaggag       60

ctggcccgct atggcgggga ggaggaagat cagcccatct acttggcagt gaagggagtg      120

gtgtttgatg tcacctccgg aaaggagttt tatggacgag gagcccccta caatgccttg      180

acggggaagg actccactag aggggtagcc aagatgtcct tggatcctgc agacctcacc      240

catgacacta cgggtctcac ggccaaggaa ctggaggccc tggatgaggt cttcaccaaa      300

gtgtacaaag ccaaataccc catcgtcggc tacactgccc ggagaattct caatgaggat      360

ggcagcccta acctggactt caagcctgaa gaccagcccc attttgacat caaggatgag      420

ttc                                                                    423


<210>  6143
<211>  312
<212>  DNA
<213>  Homo Sapiens

<400>  6143
tattacaatg tcataattgc ctatagtctt tactacatgt ttgcttcttt tcaaagtgaa       60

ctaccatgga aaaattgttc ttcgtggtca gataaaaact gtagcagatc accaatagta      120

actcactgta atgtgagtac agtgaataaa ggaatacaag agatcatcca aatgaataaa      180

agctgggtag acatcaacaa ttttacctgc atcaacggca gtgaaattta tcagccaggg      240

cagcttccca gtgaacaata ttggaataaa gtggcgctcc aacggtcaag tggaatgaat      300

gagactggag ta                                                          312


<210>  6144
<211>  741
<212>  DNA
<213>  Homo Sapiens

<400>  6144
gagggcaact accccagtcc catcccgaaa ttccacttcg agttctcctc tgctgtgccc       60

gaagtcgtcc tgaacctctt caactgcaaa aattgtgcaa atgaagctgt ggttcaaaag      120

attttggaca gggtgctgtc aagatacgat gtccgcctga gaccgaattt tggaggtgcc      180

cctgtgcctg tgagaatatc tatttatgtc acgagcattg aacagatctc agaaatgaat      240

atggactaca cgatcacgat gttttttcat cagacttgga aagattcacg cttagcatac      300

tatgagacca ccctgaactt gaccctggac tatcggatgc atgagaagtt gtgggtccct      360

gactgctact ttctgaacag caaggatgct ttcgtgcatg atgtgactgt ggagaatcgc      420

gtgtttcagc ttcacccaga tggaacggtg cggtacggca tccgactcac cactacagca      480

gcttgttccc tggatctgca taaattccct atggacaagc aggcctgcaa cctggtggta      540

gagagctatg gttacacggt tgaagacatc atattattct gggatgacaa tgggaacgcc      600

atccacatga ctgaggagct gcatatccct cagttcactt tcctgggaag gacgattact      660

agcaaggagg tgtatttcta cacaggttcc tacatacgcc tgatactgaa gttccaggtt      720

cagagggaag ttaacagcta c                                                741


<210>  6145
<211>  720
<212>  DNA
<213>  Homo Sapiens

<400>  6145
gtagtcggag ggactgaggc cgggaggaat tcctggccct ctcagatttc cctccagtac       60

cggtctggag gttcccggta tcacacctgt ggagggaccc ttatcagaca gaactgggtg      120

atgacagctg ctcactgcgt ggattaccag aagactttcc gcgtggtggc tggagaccat      180

aacctgagcc agaatgatgg cactgagcag tacgtgagtg tgcagaagat cgtggtgcat      240

ccatactgga acagcgataa cgtggctgcc ggctatgaca tcgccctgct gcgcctggcc      300

cagagcgtta ccctcaatag ctatgtccag ctgggtgttc tgccccagga gggagccatc      360

ctggctaaca acagtccctg ctacatcaca ggctggggca agaccaagac caatgggcag      420

ctggcccaga ccctgcagca ggcttacctg ccctctgtgg actacgccat ctgctccagc      480

tcctcctact ggggctccac tgtgaagaac accatggtgt gtgctggtgg agatggagtt      540

cgctctggat gccagggtga ctctgggggc cccctccatt gcttggtgaa tggcaagtat      600

tctgtccatg gagtgaccag ctttgtgtcc agccggggct gtaatgtctc caggaagcct      660

acagtcttca cccaggtctc tgcttacatc tcctggataa ataatgtcat cgcctccaac      720


<210>  6146
<211>  375
<212>  DNA
<213>  Homo Sapiens

<400>  6146
gggatcctga acctgaacaa gatggtcaag caagtgactg ggaaaatgcc catcctctcc       60

tactggccct acggctgtca ctgcggacta ggtggcagag gccaacccaa agatgccacg      120

gactggtgct gccagaccca tgactgctgc tatgaccacc tgaagaccca ggggtgcagc      180

atctacaagg actattacag atacaacttt tcccagggga acatccactg ctctgacaag      240

ggaagctggt gtgagcagca gctgtgtgcc tgtgacaagg aggtggcctt ctgcctgaag      300

cgcaacctgg acacctacca gaagcgactg cgtttctact ggcggcccca ctgccggggg      360

cagacccctg ggtgc                                                       375


<210>  6147
<211>  222
<212>  DNA
<213>  Homo Sapiens

<400>  6147
aatctcacaa ccattgcatc ttggctgtca tggcttcagt acttcagcat tccacgatat       60

ggatttacgg ctttgcagca taatgaattt ttgggacaaa acttctgccc aggactcaat      120

gcaacaggaa acaatccttg taactatgca acatgtactg gcgaagaata tttggtaaag      180

cagggcatcg atctctcacc ctggggcttg tggaagaatc ac                         222


<210>  6148
<211>  1371
<212>  DNA
<213>  Homo Sapiens

<400>  6148
tctcttctag agccgaggga cccggtggcc tcgtcgctca gcccctattt cggcaccaag       60

actcgctacg aggatgtcaa ccccgtgcta ttgtcgggcc ccgaggctcc gtggcgggac      120

cctgagctgc tggaggggac ctgcaccccg gtgcagctgg tcgccctcat tcgccacggc      180

acccgctacc ccacggtcaa acagatccgc aagctgaggc agctgcacgg gttgctgcag      240

gcccgcgggt ccagggatgg cggggctagt agtaccggca gccgcgacct gggtgcagcg      300

ctggccgact ggcctttgtg gtacgcggac tggatggacg ggcagctagt agagaaggga      360

cggcaggata tgcgacagct ggcgctgcgt ctggcctcgc tcttcccggc ccttttcagc      420

cgtgagaact acggccgcct gcggctcatc accagttcca agcaccgctg catggatagc      480

agcgccgcct tcctgcaggg gctgtggcag cactaccacc ctggcttgcc gccgccggac      540

gtcgcagata tggagtttgg acctccaaca gttaatgata aactaatgag attttttgat      600

cactgtgaga agtttttaac tgaagtagaa aaaaatgcta cagctcttta tcacgtggaa      660

gccttcaaaa ctggaccaga aatgcagaac attttaaaaa aagttgcagc tactttgcaa      720

gtgccagtaa atgatttaaa tgcagattta attcaagtag cctttttcac ctgttcattt      780

gacctggcaa ttaaaggtgt taaatctcct tggtgtgatg tttttgacat agatgatgca      840

aaggtattag aatatttaaa tgatctgaaa caatattgga aaagaggata tgggtatact      900

attaacagtc gatccagctg caccttgttt caggatatct ttcagcactt ggacaaagca      960

gttgaacaga aacaaaggtc tcagccaatt tcttctccag tcatcctcca gtttggtcat     1020

gcagagactc ttcttccact gctttctctc atgggctact tcaaagacaa ggaaccccta     1080

acagcgtaca attacaaaaa acaaatgcat cggaagttcc gaagtggtct cattgtacct     1140

tatgcctcga acctgatatt tgtgctttac cactgtgaaa atgctaagac tcctaaagaa     1200

caattccgag tgcagatgtt attaaatgaa aaggtgttac ctttggctta ctcacaagaa     1260

actgtttcat tttatgaaga tctgaagaac cactacaagg acatccttca gagttgtcaa     1320

accagtgaag aatgtgaatt agcaagggct aacagtacat ctgatgaact a              1371


<210>  6149
<211>  1269
<212>  DNA
<213>  Homo Sapiens

<400>  6149
gcaccccctc catgccgctg tatgaccagt agctcccctt accaagagtt tctatggaga       60

atgcagcgtc ccggaaatat tgatgcccca tcgtatagga gtctttctaa gggaaccccc      120

accttcactg cccacaccca tatgccccgc aactgctatc actctgccac tctttgcatg      180

catgcaaata ctcattattg gacaggaaaa atgattaatc ctagttgtcc tggaggactt      240

ggagtcactg tctgttggac ttacttcacc caaactggta tgtctgatgg gggtggagtt      300

caagatcagg caagagaaaa acatgtaaaa gaagtaatct cccaactcac ccgggtacat      360

ggcacctcta gcccctacaa aggactagat ctctcaaaac tacatgaaac cctccgtacc      420

catactcgcc tggtaagcct atttaatacc accctcactg ggctccatga ggtctcggcc      480

caaaacccta ctaactgttg gatatgcctc cccctgaact tcaggccata tgtttcaatc      540

cctgtacctg aacaatggaa caacttcagc acagaaataa acaccacttc cgttttagta      600

ggacctcttg tttccaatct ggaaataacc catacctcaa acctcacctg tgtaaaattt      660

agcaatacta catacacaac caactcccaa tgcatcaggt gggtaactcc tcccacacaa      720

atagtctgcc taccctcagg aatatttttt gtctgtggta cctcagccta tcgttgtttg      780

aatggctctt cagaatctat gtgcttcctc tcattcttag tgccccctat gaccatctac      840

actgaacaag atttatacag ttatgtcata tctaagcccc gcaacaaaag agtacccatt      900

cttccttttg ttataggagc aggagtgcta ggtgcactag gtactggcat tggcggtatc      960

acaacctcta ctcagttcta ctacaaacta tctcaagaac taaatgggga catggaacgg     1020

gtcgccgact ccctggtcac cttgcaagat caacttaact ccctagcagc agtagtcctt     1080

caaaatcgaa gagctttaga cttgctaacc gctgaaagag ggggaacctg tttattttta     1140

ggggaagaat gctgttatta tgttaatcaa tccggaatcg tcactgagaa agttaaagaa     1200

attcgagatc gaatacaacg tagagcagag gagcttcgaa acactggacc ctggggcctc     1260

ctcagccaa                                                             1269


<210>  6150
<211>  2136
<212>  DNA
<213>  Homo Sapiens

<400>  6150
cccaaaaaag ccaactcact ggccccccag gacctggacc tggagatcct ggagaccgtc       60

atggggcagc tggatgccca caggatccgg gagaacctca gagaactctc cagggagcca      120

cacctggcct ccagccctcg ggatgaggac ctggtgcagc tgctgctgca gcgctggaag      180

gacccagagt caggcctgga ctcggccgag gcctccacgt acgaagtgct gctgtccttc      240

cctagccagg agcagcccaa cgtcgtggac atcgtgggcc ccactggggg catcatccac      300

tcctgccacc ggactgagga gaacgtgacc ggggagcaag gggggccaga tgtggtacaa      360

ccctatgctg cctatgctcc ttctggaacc ccacagggcc tcctcgtcta tgccaaccgg      420

ggcgcggaag aagactttaa ggagctacag actcagggca tcaaacttga aggcaccatt      480

gccctgactc gatatggggg tgtagggcgt ggggccaagg ctgtgaacgc tgccaagcac      540

ggggtagctg gggtgctggt gtacacagac cctgccgaca tcaacgatgg gctgagctca      600

cccgacgaaa cctttcccaa ctcctggtac ctgcccccct caggagtgga gcgaggctcc      660

tactacgagt attttgggga ccctctgact ccctaccttc cagccgtccc ctcttccttc      720

cgcgtggacc ttgccaatgt ctccggattt cccccaattc ctacacagcc cattggcttc      780

caggatgcaa gagacctgct ctgtaacctc aacggaactt tggccccagc cacctggcag      840

ggagcactgg gctgccacta caggttgggt cccggcttcc ggcctgacgg agacttccca      900

gcagacagcc aggtgaatgt gagcgtctac aaccgcctgg agctgaggaa ctcttccaac      960

gtcctgggca tcatccgtgg ggctgtggag cctgatcgct acgtgctgta tgggaaccac     1020

cgagacagct gggtgcacgg ggctgtggac cccagcagtg gcaccgccgt cctcctggag     1080

ctctcccgtg tcctggggac cctgctgaag aagggcacct ggcgtcctcg cagatcaatc     1140

gtgtttgcga gctggggggc tgaggagttt gggctcattg gctccacgga attcacagaa     1200

gagttcttca acaagctgca ggagcgcacg gtggcctaca tcaacgtgga catctcggtg     1260

tttgccaacg ctacccttag ggtgcagggg acgccccctg tccagagcgt cgtcttctct     1320

gcaaccaaag agatccgctc accaggccct ggcgacctga gcatctacga caactggatc     1380

cggtacttca accgcagcag cccggtgtac ggcctggtcc ccagcttggg ttctctgggt     1440

gctggcagcg actatgcacc cttcgttcac ttcctgggca tctcctccat ggacattgcc     1500

tatacctatg accggagcaa gacttcagcc aggatctacc ccacctacca cacagccttt     1560

gacacctttg actatgtgga caagtttttg gacccgggct tcagcagcca tcaggctgtg     1620

gcccggacag cggggagtgt gattctccgg ctcagtgaca gcttcttcct gcccctcaaa     1680

gtcagtgact acagtgagac actccgcagc ttcctgcagg cagcccagca agatcttggg     1740

gccctgctgg agcagcacag catcagcctg gggcctctgg tgactgcagt ggagaagttt     1800

gaggcagaag ctgcagcctt gggccaacgc atatcaacac tgcagaaggg cagccctgac     1860

cccctgcagg tccggatgct caatgaccag ttgatgctct tggaacggac ctttctgaac     1920

cctagagcct tcccagagga acgctactac agccatgtgc tctgggcacc tcgcacgggc     1980

tccgtagtca cattcccggg cctatccaat gcctgctcca gggccaggga cacagcttct     2040

ggatctgaag cttgggctga ggtccagaga cagctcagca ttgtggtgac agccctggag     2100

ggtgcggcag ccaccctgag gcctgtggct gacctc                               2136


<210>  6151
<211>  1299
<212>  DNA
<213>  Homo Sapiens

<400>  6151
cagccgactt tcatcaacag cgttcttcca atctcagcag cccttcccag cctggatcag       60

aagaagcgtg gtggccataa agcatgctgc ctgctgacgc ctcctccacc accactgttc      120

ccaccaccat tcttcagagg tggccgaagt ccgcttctct ccccagacat gaagaatctc      180

atgctggaac tggagacctc gcagtccccg tgcatgcaag gctcgctagg ctcccctggg      240

cctcccggcc cccagggtcc accggggctt cctggcaaga caggaccaaa gggagaaaag      300

ggggagcttg gccgaccagg aaggaagggt agacctggcc ccccaggtgt tcctggcatg      360

cctgggccca tcggttggcc aggccctgaa ggacccaggg gtgaaaaagg tgacctgggt      420

atgatgggct tgccagggtc aagaggacca atgggctcca agggctaccc tggatccaga      480

ggggaaaagg gatccagagg tgaaaagggt gacctgggtc ccaaaggaga aaagggtttc      540

ccaggatttc ctggaatgtt ggggcagaaa ggtgaaatgg gtccaaaagg tgaacctggg      600

atagcaggac accgaggacc cacaggaaga ccaggaaaac gaggcaagca gggacagaaa      660

ggggatagtg gagttatggg cccaccaggc aagcctgggc cttctggtca acctggccgt      720

ccggggcccc caggcccccc acctgcagga caacttataa tgggacccaa aggggaaaga      780

ggatttcccg ggcctccagg aagatgtctt tgtggaccca ctatgaatgt gaataaccct      840

tcctacgggg aatctgtgta tgggcccagt tccccgcgag ttcctgtgat ttttgtggtc      900

aacaaccagg aggagcttga gaggctgaac acccaaaacg ccattgcctt ccgcagagac      960

cagagatctc tgtacttcaa ggacagcctt ggctggctcc ccatccagct gacccctttc     1020

taccctgtgg attacactgc agaccagcac ggcacctgtg gggatgggct cctgcagcct     1080

ggggaggagt gtgacgacgg taacagcgat gtgggtgacg actgcatccg ctgtcaccgt     1140

gcctactgtg gagatggtca ccggcatgag ggtgtggagg actgtgacgg ctctgacttt     1200

ggctacctga catgcgagac ctatctccct gggtcatatg gagacctgca atgcacccag     1260

tactgctaca tcgactccac gccctgccgc tacttcacc                            1299


<210>  6152
<211>  1524
<212>  DNA
<213>  Homo Sapiens

<400>  6152
caggacgtcg tggacctgga cttcttcacc caggagccgc tgcacctggt gagcccctcg       60

ttcctgtccg tcaccattga cgccaacctg gccacggacc cgcggttcct catcctcctg      120

ggttctccaa agcttcgtac cttggccaga ggcttgtctc ctgcgtacct gaggtttggt      180

ggcaccaaga cagacttcct aattttcgat cccaagaagg aatcaacctt tgaagagaga      240

agttactggc aatctcaagt caaccaggat atttgcaaat atggatccat ccctcctgat      300

gtggaggaga agttacggtt ggaatggccc taccaggagc aattgctact ccgagaacac      360

taccagaaaa agttcaagaa cagcacctac tcaagaagct ctgtagatgt gctatacact      420

tttgcaaact gctcaggact ggacttgatc tttggcctaa atgcgttatt aagaacagca      480

gatttgcagt ggaacagttc taatgctcag ttgctcctgg actactgctc ttccaagggg      540

tataacattt cttgggaact aggcaatgaa cctaacagtt tccttaagaa ggctgatatt      600

ttcatcaatg ggtcgcagtt aggagaagat tttattcaat tgcataaact tctaagaaag      660

tccaccttca aaaatgcaaa actctatggt cctgatgttg gtcagcctcg aagaaagacg      720

gctaagatgc tgaagagctt cctgaaggct ggtggagaag tgattgattc agttacatgg      780

catcactact atttgaatgg acggactgct accagggaag attttctaaa ccctgatgta      840

ttggacattt ttatttcatc tgtgcaaaaa gttttccagg tggttgagag caccaggcct      900

ggcaagaagg tctggttagg agaaacaagc tctgcatatg gaggcggagc gcccttgcta      960

tccgacacct ttgcagctgg ctttatgtgg ctggataaat tgggcctgtc agcccgaatg     1020

ggaatagaag tggtgatgag gcaagtattc tttggagcag gaaactacca tttagtggat     1080

gaaaacttcg atcctttacc tgattattgg ctatctcttc tgttcaagaa attggtgggc     1140

accaaggtgt taatggcaag cgtgcaaggt tcaaagagaa ggaagcttcg agtatacctt     1200

cattgcacaa acactgacaa tccaaggtat aaagaaggag atttaactct gtatgccata     1260

aacctccata atgtcaccaa gtacttgcgg ttaccctatc ctttttctaa caagcaagtg     1320

gataaatacc ttctaagacc tttgggacct catggattac tttccaaatc tgtccaactc     1380

aatggtctaa ctctaaagat ggtggatgat caaaccttgc cacctttaat ggaaaaacct     1440

ctccggccag gaagttcact gggcttgcca gctttctcat atagtttttt tgtgataaga     1500

aatgccaaag ttgctgcttg catc                                            1524


<210>  6153
<211>  279
<212>  DNA
<213>  Homo Sapiens

<400>  6153
acagcccaga agccctattg caataccagc tggatcctgg cagtgggccc ccacctgtcc       60

aaagctgagc agctgaatct gaccataccc caagcaccca atggcagttt cctgacatgc      120

ttcatgtacc ttcctgtgcc ttggaatctg gattctatca tccagtttgg cctcaatgac      180

acagacacat gccaagatgg gtggatctat cctgacgcta agaagcgatc gctgatcaat      240

gagtttgact tggtatgtgg catggagacg aagaaggac                             279


<210>  6154
<211>  486
<212>  DNA
<213>  Homo Sapiens

<400>  6154
cggaggagcc aggatctcca ctgtggagca tgcagggctc tggtggatga actagaatgg       60

gaaattgccc aggtggaccc caagaagacc attcagatgg gatctttccg gatcaatcca      120

gatggcagcc agtcagtggt ggaggtgcct tatgcccgct cagaggccca cctcacagag      180

ctgctggagg agatatgtga ccggatgaag gagtatgggg aacagattga tccttccacc      240

catcgcaaga actacgtacg tgtagtgggc cggaatggag aatccagtga actggaccta      300

caaggcatcc gaatcgactc agatattagc ggcaccctca agtttgcgtg tgagagcatt      360

gtggaggaat acgaggatga actcattgaa ttcttttccc gagaggctga caatgttaaa      420

gacaaacttt gcagtaagcg aacagatctt tgtgaccatg ccctgcacat atcgcatgat      480

gagcta                                                                 486


<210>  6155
<211>  1239
<212>  DNA
<213>  Homo Sapiens

<400>  6155
cgccgccgcc aggcgccggc cgggtccccg cggggcctca ggaagggggc ggcccccgcg       60

cgggagagac gcggccgaga acagtccact ttggaaagtg aagaatggaa tccttgggaa      120

ggagatgaaa aaaatgagca acaacacaga tttaaaacta gccttcaaat attagataaa      180

tccacgaaag gaaaaacaga tctcagtgta caaatctggg gcaaagctgc cattggcttg      240

tatctctggg agcatatttt tgaaggctta cttgatccca gcgatgtgac tgctcaatgg      300

agagaaggaa agtcaatcgt aggaagaaca cagtacagct tcatcactgg tccagctgta      360

ataccagggt acttctccgt tgatgtgaat aatgtggtac tcattttaaa tggaagagaa      420

aaagcaaaga tcttttatgc cacccagtgg ttactttatg cacaaaattt agtgcaaatt      480

caaaaactcc agcatcttgc tgttgttttg ctcggaaatg aacattgtga taatgagtgg      540

ataaacccat tcctcaaaag aaatggaggc ttcgtggagc tgcttttcat aatatatgac      600

agcccctgga ttaatgacgt ggatgttttt cagtggcctt taggagtagc aacatacagg      660

aattttcctg tggtggaggc aagttggtca atgctgcatg atgagaggcc atatttatgt      720

aatttcttag gaacgattta tgaaaattca tccagacagg cactaatgaa cattttgaaa      780

aaagatggga acgataagct ttgttgggtt tcagcaagag aacactggca gcctcaggaa      840

acaaatgaaa gtcttaagaa ttaccaagat gccttgcttc agagtgatct cacattgtgc      900

ccggtcggag taaacacaga atgctatcga atctatgagg cttgctccta tggctccatt      960

cctgtggtgg aagacgtgat gacagctggc aactgtggga atacatctgt gcaccacggt     1020

gctcctctgc agttactcaa gtccatgggt gctcccttta tctttatcaa gaactggaag     1080

gaactccctg ctgttttaga aaaagagaaa actataattt tacaagaaaa aattgaaaga     1140

agaaaaatgt tacttcagtg gtatcagcac ttcaagacag agcttaaaat gaaatttact     1200

aatattttag aaagctcatt tttaatgaat aataaaagt                            1239


<210>  6156
<211>  2958
<212>  DNA
<213>  Homo Sapiens

<400>  6156
gccggcccca tccgggcctt cgtggtgccc cacagccaca tggacgtggg ctgggtctac       60

actgtgcagg aaagcatgcg ggcgtacgcc gccaatgtct acacctcagt ggtggaagag      120

ctggcccgcg gccagcagcg ccggttcatc gctgtggagc aggagttttt ccggctgtgg      180

tgggatggcg tcgcctcgga ccagcagaaa taccaggtcc gccagctcct ggaggaagga      240

cgcctggaat ttgtcatcgg aggccaggtc atgcatgacg aggctgtgac gcaccttgat      300

gaccagatcc tgcagctcac agaaggacac gggtttctct atgaaacatt tgggatccgg      360

ccacagttct cctggcacgt tgacccgttt ggcgcctctg ccacgacgcc caccctattt      420

gcgctggcgg gcttcaatgc ccacctcggc tcccggatcg actacgacct gaaggcagcc      480

atgcaggagg cccgggggct gcagttcgtg tggcgagggt ccccatccct ctcagagcgg      540

caggaaatct tcacgcacat catggaccag tacagctact gcaccccgtc ccacatccct      600

ttctccaaca ggtcaggatt ttactggaat ggcgtggctg tcttccccaa gcctccccca      660

gatggggtgt accccaacat gagtgagcct gtcaccccag ccaacatcaa cctctatgcc      720

gaggccctgg tggccaacgt gaagcagagg gccgcctggt tccggacacc gcacgtcctc      780

tggccctggg gatgtgacaa gcagttcttc aatgcctcgg tgcagtttgc caacatggac      840

ccgctgctgg accacatcaa cagccatgct gccgagctcg gtgtctcggt gcagtatgcc      900

acgctgggcg actacttccg tgccctgcac gctctcaatg tcacctggcg tgtccgcgac      960

caccacgact tcctgcccta ttccacagaa ccattccagg cctggacggg cttctacacg     1020

tcccgcagct cactgaaggg gctggcccgg cgagccagcg ccttgttgta tgccggggag     1080

tccatgttca cacgctacct gtggccggcc ccccgtgggc atctggaccc cacctgggcc     1140

ctgcagcagc tccagcagct tcgctgggcc gtctccgagg tccagcacca tgatgccatc     1200

actgggactg agtcccccaa ggtgagagac atgtacgcaa cgcacctggc ctcggggatg     1260

ctgggcgtgc gcaagctgat ggcctccatc gtcctagatg agctccagcc ccaggcaccc     1320

atggcggcca gctccgatgc aggacctgca ggacattttg cctcggtcta caacccgctg     1380

gcctggacgg tcaccaccat cgtcaccctg actgttggtt tccctggagt ccgcgtcaca     1440

gatgaggcgg gccacccagt gccctcgcag atccagaact caacagagac cccatctgcg     1500

tatgacctgc ttattctgac cacaatccca ggcctcagtt accggcacta cagcatcaga     1560

cccactgcag gggcccaaga gggcacccag gagccggctg ccactgtggc gagcaccctt     1620

caatttggcc gcaggctgag gagacgcacc agccatgcgg gcaggtactt ggtgcctgtg     1680

gcaaacgact gctacattgt gctgctcgac caggatacca acctgatgca cagcatctgg     1740

gagagacaga gtaaccgaac ggtgcgcgtg acccaggaat tcctggagta ccacgtcaac     1800

ggggatgtga aacagggccc catttccgat aactacctgt tcacaccggg caaggccgcg     1860

gtgcctgcgt gggaagctgt ggaaatggag attgtggcgg gacagcttgt gactgagatc     1920

cggcagtact tctacaggaa catgacagca cagaattaca cgtatgcaat ccgctcccgg     1980

ctcacccatg tgccgcaggg ccatgacggg gagctgctct gccaccggat agagcaggag     2040

taccaagccg gccccctgga gctgaaccgt gaggctgtcc tgaggaccag caccaaccta     2100

aacagccagc aggtcatcta ctcagacaac aacggctacc agatgcagcg gaggccctac     2160

gtttcctatg tgaacaacag catcgcccgg aattactacc ccatggttca gtcggccttc     2220

atggaggatg gcaaaagcag gcttgtgttg ctgtcggagc gggcacatgg catctccagc     2280

caagggaatg ggcaggtgga ggtcatgctc caccggcggc tgtggaacaa cttcgactgg     2340

gacctgggct acaacctcac gctgaacgac acctcagtcg tccacccagt gctctggctt     2400

ctgctgggat cctggtccct caccactgcc ctgcgccaga ggagcgcact ggcgctgcag     2460

cacaggcccg tggtgctgtt cggagacctc gctgggactg cgccgaagct cccaggaccc     2520

cagcagcaag aggccgtgac gctgcccccg aatcttcacc tgcagatcct gagcatccct     2580

ggctggcgct acagctccaa ccacacggag cactctcaga atctccggaa aggccatcga     2640

ggggaagccc aggctgacct ccgccgtgtc ctgctgcggc tctaccacct gtatgaagtg     2700

ggcgaggacc cagtcctgtc tcagccagta acagtgaatc tggaggctgt gctgcaggcg     2760

ctggggtccg tggtggcagt ggaggagcgc tcgctcacag ggacctggga tttgagcatg     2820

ctgcaccgct ggagctggag gacggggcct ggccgccaca gaggtgacac cacctctccc     2880

tcgaggccac caggaggccc catcatcacc gtccacccaa aggaaatccg gacgttcttt     2940

attcactttc aacagcag                                                   2958


<210>  6157
<211>  1224
<212>  DNA
<213>  Homo Sapiens

<400>  6157
tccggccagg agttctggcc cggacaatcg gcggccgata ttctgtcggg ggcggcttcc       60

cgcagacggt atcttctgta tgacgtcaac cccccggaag gcttcaacct gcgcagggat      120

gtctatatcc gaatcgcctc tctcctgaag actctgctga agacggagga gtgggtgctt      180

gtcctgcctc catggggccg cctctatcac tggcagagtc ctgacatcca ccaggtccgg      240

attccctggt ctgagttttt tgatcttcca agtctcaata aaaacatccc cgtcatcgag      300

tatgagcagt tcatcgcaga atctggtggg ccctttattg accaggttta cgtcctgcaa      360

agttacgcag aggggtggaa agaagggacc tgggaagaga aggtggacga gcggccgtgt      420

attgatcagc tcctgtactc ccaggacaag cacgagtact acagaggatg gttttggggt      480

tatgaggaga ccaggggtct aaacgtctcc tgtctgtccg tccagggctc agcctccatc      540

gtggcgcccc tgctgctgag aaacacatca gcccggtccg tgatgttaga cagagccgag      600

aacctacttc acgaccacta tggagggaaa gaatactggg atacccgtcg cagcatggtg      660

tttgccaggc acctgcggga ggtgggagac gagttcagga gcagacatct caactccacg      720

gacgacgcag acaggatccc cttccaggag gactggatga agatgaaggt caagctgggc      780

tccgcgctag ggggccccta cctgggagtc cacctgagaa gaaaagattt catctggggt      840

cacagacagg atgtacccag tctggaaggg gccgtgagga agatccgcag cctcatgaag      900

acccaccggc tggacaaggt gtttgtggcc acagatgccg tcagaaagga atatgaagag      960

ctaaaaaagc tgttacccga gatggtgagg tttgaaccca cgtgggagga gctggagctc     1020

tacaaggacg gaggcgttgc gattattgac cagtggatct gcgcacacgc caggtttttt     1080

attggcacct cagtctcaac attttctttt cggattcatg aggaaagaga aatcctgggg     1140

ttggacccca agacgacgta caacaggttc tgcggagacc aagagaaggc gtgtgagcaa     1200

cccacccact ggaagatcac ctac                                            1224


<210>  6158
<211>  678
<212>  DNA
<213>  Homo Sapiens

<400>  6158
caggctttca gcgactctaa tgatgagcga gagtcaagcc ctccagaaaa agaggaagcc       60

caagagaaga ctgggaaaac tgagccaagc ttcaccaaag aaaacagcag caagattcct      120

aaaaaaggct ttgtggaggt aactgaactc acagatgtaa catacaccag taacttggta      180

cgtctgaggc caggccacat gaatgtggtc ctcatcctgt cgaattctac caagaccagc      240

ctactacaga aatttgcttt ggaggtctac acatttactg ggagcagctg cctacacttc      300

tccttcctga gtctagataa acacagagaa tggctagaat acttactaga atttgctcaa      360

gatgcagctc caatcccaaa ccaatatgat aagcatttca tggagcgtga ctacactggt      420

tatgtactgg ctctgaatgg ccacaagaaa tacttctgcc tcttcaagcc ccaaaagaca      480

gtcgaagagg aggaagccat agggtcgtgc agtgatgttg actcttccct ctacctgggt      540

gaatctcgag ggaaaccttc ctgtggcctt ggatccaggc ccatcaaagg aaagttgagc      600

aagctctctt tatggatgga acgcctgctg gagggctcct tacagaggtt ttatatccca      660

tcatggcctg aactagac                                                    678


<210>  6159
<211>  162
<212>  DNA
<213>  Homo Sapiens

<400>  6159
ctgcccaccc aacgcgaaga cggtaacccg tgtgactttg actggagaga agtggagatc       60

ctgatgtttc tcagtgccat tgtgatgatg aagaaccgca gatccatcac tgtggagcaa      120

catataggca acattttcat gtttagtaaa gtggccaaca ca                         162


<210>  6160
<211>  813
<212>  DNA
<213>  Homo Sapiens

<400>  6160
gtcacagagc atgttctcgc caacaatgat gtttcctgtg accacccctc taacaccgtg       60

ccctctggga gcaaccagga cctgggagct ggggccgggg aagacgcccg gtcggatgac      120

agcagcagcc gcatcatcaa tggatccgac tgcgatatgc acacccagcc gtggcaggcc      180

gcgctgttgc taaggcccaa ccagctctac tgcggggcgg tgttggtgca tccacagtgg      240

ctgctcacgg ccgcccactg caggaagaaa gttttcagag tccgtctcgg ccactactcc      300

ctgtcaccag tttatgaatc tgggcagcag atgttccagg gggtcaaatc catcccccac      360

cctggctact cccaccctgg ccactctaac gacctcatgc tcatcaaact gaacagaaga      420

attcgtccca ctaaagatgt cagacccatc aacgtctcct ctcattgtcc ctctgctggg      480

acaaagtgct tggtgtctgg ctgggggaca accaagagcc cccaagtgca cttccctaag      540

gtcctccagt gcttgaatat cagcgtgcta agtcagaaaa ggtgcgagga tgcttacccg      600

agacagatag atgacaccat gttctgcgcc ggtgacaaag caggtagaga ctcctgccag      660

ggtgattctg gggggcctgt ggtctgcaat ggctccctgc agggactcgt gtcctgggga      720

gattaccctt gtgcccggcc caacagaccg ggtgtctaca cgaacctctg caagttcacc      780

aagtggatcc aggaaaccat ccaggccaac tcc                                   813


<210>  6161
<211>  306
<212>  DNA
<213>  Homo Sapiens

<400>  6161
tgctatacac ttttctacct gtttgcctcc tttgtgtctg tactaccctg gggctcctgc       60

aacaaccctt ggaatacacc agaatgcaaa gataaaacca aacttttatt agattcctgt      120

gttatcagtg accatcccaa aatacagatc aagaactcga ctttctgcat gaccgcttat      180

cccaacgtga caatggttaa tttcaccagc caggccaata agacatttgt cagtggaagt      240

gaagagtact tcaagtactt tgtgctgaag atttctgcag ggattgaata tcctggcgag      300

atcagg                                                                 306


<210>  6162
<211>  933
<212>  DNA
<213>  Homo Sapiens

<400>  6162
gacggcgacc tgacgctact atgggccgag tggcagggac gacgcccaga atgggagctg       60

actgatatgg tggtgtgggt gactggagcc tcgagtggaa ttggtgagga gctggcttac      120

cagttgtcta aactaggagt ttctcttgtg ctgtcagcca gaagagtgca tgagctggaa      180

agggtgaaaa gaagatgcct agagaatggc aatttaaaag aaaaagatat acttgttttg      240

ccccttgacc tgaccgacac tggttcccat gaagcggcta ccaaagctgt tctccaggag      300

tttggtagaa tcgacattct ggtcaacaat ggtggaatgt cccagcgttc tctgtgcatg      360

gataccagct tggatgtcta cagaaagcta atagagctta actacttagg gacggtgtcc      420

ttgacaaaat gtgttctgcc tcacatgatc gagaggaagc aaggaaagat tgttactgtg      480

aatagcatcc tgggtatcat atctgtacct ctttccattg gatactgtgc tagcaagcat      540

gctctccggg gtttttttaa tggccttcga acagaacttg ccacataccc aggtataata      600

gtttctaaca tttgcccagg acctgtgcaa tcaaatattg tggagaattc cctagctgga      660

gaagtcacaa agactatagg caataatgga gaccagtccc acaagatgac aaccagtcgt      720

tgtgtgcggc tgatgttaat cagcatggcc aatgatttga aagaagtttg gatctcagaa      780

caacctttct tgttagtaac atatttgtgg caatacatgc caacctgggc ctggtggata      840

accaacaaga tggggaagaa aaggattgag aactttaaga gtggtgtgga tgcagactct      900

tcttatttta aaatctttaa gacaaaacat gac                                   933


<210>  6163
<211>  2247
<212>  DNA
<213>  Homo Sapiens

<400>  6163
cagtatgaca gctggcccca ttaccccgag tacttccagc aaccggctcc tgagtatcac       60

cagccccagg cccccgccaa cgtggccaag attcagctgc gcctggctgg gcagaagagg      120

aagcacagcg agggccgggt ggaggtgtac tatgatggcc agtggggcac cgtgtgcgat      180

gacgacttct ccatccacgc tgcccacgtc gtctgccggg agctgggcta cgtggaggcc      240

aagtcctgga ctgccagctc ctcctacggc aagggagaag ggcccatctg gttagacaat      300

ctccactgta ctggcaacga ggcgaccctt gcagcatgca cctccaatgg ctggggcgtc      360

actgactgca agcacacgga ggatgtcggt gtggtgtgca gcgacaaaag gattcctggg      420

ttcaaatttg acaattcgtt gatcaaccag atagagaacc tgaatatcca ggtggaggac      480

attcggattc gagccatcct ctcaacctac cgcaagcgca ccccagtgat ggagggctac      540

gtggaggtga aggagggcaa gacctggaag cagatctgtg acaagcactg gacggccaag      600

aattcccgcg tggtctgcgg catgtttggc ttccctgggg agaggacata caataccaaa      660

gtgtacaaaa tgtttgcctc acggaggaag cagcgctact ggccattctc catggactgc      720

accggcacag aggcccacat ctccagctgc aagctgggcc cccaggtgtc actggacccc      780

atgaagaatg tcacctgcga gaatgggcta ccggccgtgg tgagttgtgt gcctgggcag      840

gtcttcagcc ctgacggacc ctcgagattc cggaaagcgt acaagccaga gcaacccctg      900

gtgcgactga gaggcggtgc ctacatcggg gagggccgcg tggaggtgct caaaaatgga      960

gagtggggga ccgtctgcga cgacaagtgg gacctggtgt cggccagtgt ggtctgcaga     1020

gagctgggct ttgggagtgc caaagaggca gtcactggct cccgactggg gcaagggatc     1080

ggacccatcc acctcaacga gatccagtgc acaggcaatg agaagtccat tatagactgc     1140

aagttcaatg ccgagtctca gggctgcaac cacgaggagg atgctggtgt gagatgcaac     1200

acccctgcca tgggcttgca gaagaagctg cgcctgaacg gcggccgcaa tccctacgag     1260

ggccgagtgg aggtgctggt ggagagaaac gggtcccttg tgtgggggat ggtgtgtggc     1320

caaaactggg gcatcgtgga ggccatggtg gtctgccgcc agctgggcct gggattcgcc     1380

agcaacgcct tccaggagac ctggtattgg cacggagatg tcaacagcaa caaagtggtc     1440

atgagtggag tgaagtgctc gggaacggag ctgtccctgg cgcactgccg ccacgacggg     1500

gaggacgtgg cctgccccca gggcggagtg cagtacgggg ccggagttgc ctgctcagaa     1560

accgcccctg acctggtcct caatgcggag atggtgcagc agaccaccta cctggaggac     1620

cggcccatgt tcctgctgca gtgtgccatg gaggagaact gcctctcggc ctcagccgcg     1680

cagaccgacc ccaccacggg ctaccgccgg ctcctgcgct tctcctccca gatccacaac     1740

aatggccagt ccgacttccg gcccaagaac ggccgccacg cgtggatctg gcacgactgt     1800

cacaggcact accacagcat ggaggtgttc acccactatg acctgctgaa cctcaatggc     1860

accaaggtgg cagagggcca caaggccagc ttctgcttgg aggacacaga atgtgaagga     1920

gacatccaga agaattacga gtgtgccaac ttcggcgatc agggcatcac catgggctgc     1980

tgggacatgt accgccatga catcgactgc cagtgggttg acatcactga cgtgccccct     2040

ggagactacc tgttccaggt tgttattaac cccaacttcg aggttgcaga atccgattac     2100

tccaacaaca tcatgaaatg caggagccgc tatgacggcc accgcatctg gatgtacaac     2160

tgccacatag gtggttcctt cagcgaagag acggaaaaaa agtttgagca cttcagcggg     2220

ctcttaaaca accagctgtc cccgcag                                         2247


<210>  6164
<211>  1380
<212>  DNA
<213>  Homo Sapiens

<400>  6164
gaacattctg aaaatgtgca tatttcagga gtgtcaactg cttgtggaga gactccagag       60

caaatacgag caccaagtgg cataatcaca agcccaggct ggccttctga atatcctgca      120

aaaatcaact gtagctggtt cataagggca aacccaggcg aaatcattac tataagtttt      180

caggattttg atattcaagg atccagaagg tgcaatttgg actggttgac aatagaaaca      240

tacaagaata ttgaaagtta cagagcttgt ggttccacaa ttccacctcc gtatatctct      300

tcacaagacc acatctggat taggtttcat tcggatgaca acatctctag aaagggtttc      360

agactggcat atttttcagg gaaatctgag gaaccaaatt gtgcttgtga tcagtttcgt      420

tgtggtaatg gaaagtgtat accagaagcc tggaaatgta ataacatgga tgaatgtgga      480

gatagttccg atgaagagat ctgtgccaaa gaagcaaatc ctccaactgc tgctgctttt      540

caaccctgtg cttacaacca gttccagtgt ttatcccgtt ttaccaaagt ttacacttgc      600

ctccccgaat ctttaaaatg tgatgggaac attgactgcc ttgacctagg agatgagata      660

gactgtgatg tgccaacatg tgggcaatgg ctaaaatatt tttatggtac ttttaattct      720

cccaattatc cagactttta tcctcctgga agcaattgca cctggttaat agacactggt      780

gatcaccgta aagtcatttt acgcttcact gactttaaac ttgatggtac tggttatggt      840

gattatgtca aaatatatga tggattagag gagaatccac acaagctttt gcgtgtgttg      900

acagcttttg attctcatgc acctcttaca gttgtttctt cttctggaca gataagggta      960

catttttgtg ctgataaagt gaatgctgca aggggattta atgctactta ccaagtagat     1020

gggttctgtt tgccatggga aataccctgt ggaggtaact gggggtgtta tactgagcag     1080

cagcgttgtg atgggtattg gcattgccca aatggaaggg atgaaaccaa ttgtaccatg     1140

tgccagaagg aagaatttcc atgttcccga aatggtgtct gttatcctcg ttctgatcgc     1200

tgcaactacc agaatcattg cccaaatggc tcagatgaaa aaaactgctt tttttgccaa     1260

ccaggaaatt tccattgtaa aaacaatcgt tgtgtgtttg aaagttgggt gtgtgattct     1320

caagatgact gtggtgatgg cagcgatgaa gaaaattgcc cagtaatcgt gcctacaaga     1380


<210>  6165
<211>  168
<212>  DNA
<213>  Homo Sapiens

<400>  6165
tggactgact gttggatggt gaatgctgat gactctctgg aggtgagcac aaaatgccga       60

ggcctctggt gggaatgcgt cacaaatgct tttgatggga ttcgcacctg tgatgagtac      120

gattccatac ttgcggagca tcccttgaag ctggtggtaa ctcgagcg                   168


<210>  6166
<211>  672
<212>  DNA
<213>  Homo Sapiens

<400>  6166
atcataaacg gcgaggactg cagcccgcac tcgcagccct ggcaggcggc actggtcatg       60

gaaaacgaat tgttctgctc gggcgtcctg gtgcatccgc agtgggtgct gtcagccgca      120

cactgtttcc agaactccta caccatcggg ctgggcctac acagtcttga ggccgaccaa      180

gagccaggga gccagatggt ggaggccagc ctctccgtac ggcacccaga gtacaacaga      240

cccttgctcg ctaacgacct catgctcatc aagttggacg aatccgtgtc cgagtctgac      300

accatccgga gcatcagcat tgcttcgcag tgccctaccg cggggaactc ttgcctcgtt      360

tctggctggg gtctgctggc gaacggcaga atgcctaccg tgctgcagtg cgtgaacgtg      420

tcggtggtgt ctgaggaggt ctgcagtaag ctctatgacc cgctgtacca ccccagcatg      480

ttctgcgccg gcggagggca agaccagaag gactcctgca acggtgactc tggggggccc      540

ctgatctgca acgggtactt gcagggcctt gtgtctttcg gaaaagcccc gtgtggccaa      600

gttggcgtgc caggtgtcta caccaacctc tgcaaattca ctgagtggat agagaaaacc      660

gtccaggcca gt                                                          672


<210>  6167
<211>  1302
<212>  DNA
<213>  Homo Sapiens

<400>  6167
acccgcgacg tccgggagcc gcccgccctc aagtatggca tcgtcctgga cgctggttct       60

tcacacacgt ccatgtttat ctacaagtgg ccggcagaca aggagaacga cacaggcatt      120

gtgggccagc acagctcctg tgatgttcca ggtgggggca tctccagcta tgcagacaac      180

ccttctgggg ccagccagag tcttgttgga tgcctcgaac aggcgcttca ggatgtgccc      240

aaagagagac acgcgggcac acccctctac ctgggagcca cagcgggtat gcgcctgctc      300

aacctgacca atccagaggc ctcgaccagt gtgctcatgg cagtgactca cacactgacc      360

cagtacccct ttgacttccg gggtgcacgc atcctctcgg gccaggaaga gggggtgttt      420

ggctgggtga ctgccaacta cctgctggag aacttcatca agtacggctg ggtgggccgg      480

tggttccggc cacggaaggg gacactgggg gccatggacc tggggggtgc ctctacccag      540

atcacttttg agacaaccag tccagctgag gacagagcca gcgaggtcca gctgcatctc      600

tacggccagc actaccgagt ctacacccac agcttcctct gctatggccg tgaccaggtc      660

ctccagaggc tgctggccag tgccctccag acccacggct tccacccctg ctggccgagg      720

ggcttttcca cccaagtgct gctcggggat gtgtaccagt caccatgcac catggcccag      780

cggccccaga acttcaacag cagtgccagg gtcagcctgt cagggagcag tgacccccac      840

ctctgccgag atctggtttc tgggctcttc agcttctcct cctgcccctt ctcccgatgc      900

tctttcaatg gggtcttcca gcccccagtg gctgggaact ttgtcgcctt ctctgccttc      960

ttctacactg tggacttttt gcggacttcg atggggctgc ccgtggccac cctgcagcag     1020

ctggaagcag ccgcagtgaa tgtctgcaac cagacctggg ctcagctgca agctcgggtg     1080

ccagggcaac gggcccgcct ggccgactac tgcgccgggg ccatgttcgt gcagcagctg     1140

ctgagtcgcg gctacggctt cgacgagcgc gccttcggcg gcgtgatctt ccagaagaag     1200

gccgcggaca ctgcagtggg ctgggcgctc ggctacatgc tgaacctgac caacctgatc     1260

cccgccgacc cgccggggct gcgcaagggc acagacttca gc                        1302


<210>  6168
<211>  507
<212>  DNA
<213>  Homo Sapiens

<400>  6168
cggggtcaaa cagaggagag catgaatgag agtcatcctc gcaagtgtgc agagtctttt       60

gagatgtggg atgatcgtga ctctcactgt aggcgcccta agtttgaagg gcatccccct      120

gagtcttgga agtggatcct tgcaccggtc attctttata tctgtgaaag gatcctccgg      180

ttttaccgct cccagcagaa ggttgtgatt accaaggttg ttatgcaccc atccaaagtt      240

ttggaattgc agatgaacaa gcgtggcttc agcatggaag tggggcagta tatctttgtt      300

aattgcccct caatctctct cctggaatgg catcctttta ctttgacctc tgctccagag      360

gaagatttct tctccattca tatccgagca gcaggggact ggacagaaaa tctcataagg      420

gctttcgaac aacaatattc accaattccc aggattgaag tggatggtcc ctttggcaca      480

gccagtgagg atgttttcca gtatgaa                                          507


<210>  6169
<211>  1440
<212>  DNA
<213>  Homo Sapiens

<400>  6169
agccccgtac cttttggtcc agagggacgg ctggaagata agctccacaa acccaaagct       60

acacagactg aggtcaaacc atctgtgagg tttaacctcc gcacctccaa ggacccagag      120

catgaaggat gctacctctc cgtcggccac agccagccct tagaagactg cagtttcaac      180

atgacagcta aaaccttttt catcattcac ggatggacga tgagcggtat ctttgaaaac      240

tggctgcaca aactcgtgtc agccctgcac acaagagaga aagacgccaa tgtagttgtg      300

gttgactggc tccccctggc ccaccagctt tacacggatg cggtcaataa taccagggtg      360

gtgggacaca gcattgccag gatgctcgac tggctgcagg agaaggacga tttttctctc      420

gggaatgtcc acttgatcgg ctacagcctc ggagcgcacg tggccgggta tgcaggcaac      480

ttcgtgaaag gaacggtggg ccgaatcaca ggtttggatc ctgccgggcc catgtttgaa      540

ggggccgaca tccacaagag gctctctccg gacgatgcag attttgtgga tgtcctccac      600

acctacacgc gttccttcgg cttgagcatt ggtattcaga tgcctgtggg ccacattgac      660

atctacccca atgggggtga cttccagcca ggctgtggac tcaacgatgt cttgggatca      720

attgcatatg gaacaatcac agaggtggta aaatgtgagc atgagcgagc cgtccacctc      780

tttgttgact ctctggtgaa tcaggacaag ccgagttttg ccttccagtg cactgactcc      840

aatcgcttca aaaaggggat ctgtctgagc tgccgcaaga accgttgtaa tagcattggc      900

tacaatgcca agaaaatgag gaacaagagg aacagcaaaa tgtacctaaa aacccgggca      960

ggcatgcctt tcagagttta ccattatcag atgaaaatcc atgtcttcag ttacaagaac     1020

atgggagaaa ttgagcccac cttttacgtc accctttatg gcactaatgc agattcccag     1080

actctgccac tggaaatagt ggagcggatc gagcagaatg ccaccaacac cttcctggtc     1140

tacaccgagg aggacttggg agacctcttg aagatccagc tcacctggga gggggcctct     1200

cagtcttggt acaacctgtg gaaggagttt cgcagctacc tgtctcaacc ccgcaacccc     1260

ggacgggagc tgaatatcag gcgcatccgg gtgaagtctg gggaaaccca gcggaaactg     1320

acattttgta cagaagaccc tgagaacacc agcatatccc caggccagga gctctggttt     1380

cgcaagtgtc gggatggctg gaggatgaaa aacgaaacca gtcccactgt ggagcttccc     1440


<210>  6170
<211>  2337
<212>  DNA
<213>  Homo Sapiens

<400>  6170
tggcatttgc agtaccggga cgtgcgtgtc cagaaggtct tcaatggcta catgaggatc       60

acaaatgaga attttgtgga tgcctacgag aactccaact ccactgagtt tgtaagcctg      120

gccagcaagg tgaaggacgc gctgaagctg ctgtacagcg gagtcccatt cctgggcccc      180

taccacaagg agtcggctgt gacggccttc agcgagggca gcgtcatcgc ctactactgg      240

tctgagttca gcatcccgca gcacctggtg gaggaggccg agcgcgtcat ggccgaggag      300

cgcgtagtca tgctgccccc gcgggcgcgc tccctgaagt cctttgtggt cacctcagtg      360

gtggctttcc ccacggactc caaaacagta cagaggaccc aggacaacag ctgcagcttt      420

ggcctgcacg cccgcggtgt ggagctgatg cgcttcacca cgcccggctt ccctgacagc      480

ccctaccccg ctcatgcccg ctgccagtgg gccctgcggg gggacgccga ctcagtgctg      540

agcctcacct tccgcagctt tgaccttgcg tcctgcgacg agcgcggcag cgacctggtg      600

acggtgtaca acaccctgag ccccatggag ccccacgccc tggtgcagtt gtgtggcacc      660

taccctccct cctacaacct gaccttccac tcctcccaga acgtcctgct catcacactg      720

ataaccaaca ctgagcggcg gcatcccggc tttgaggcca ccttcttcca gctgcctagg      780

atgagcagct gtggaggccg cttacgtaaa gcccagggga cattcaacag cccctactac      840

ccaggccact acccacccaa cattgactgc acatggaaca ttgaggtgcc caacaaccag      900

catgtgaagg tgcgcttcaa attcttctac ctgctggagc ccggcgtgcc tgcgggcacc      960

tgccccaagg actacgtgga gatcaatggg gagaaatact gcggagagag gtcccagttc     1020

gtcgtcacca gcaacagcaa caagatcaca gttcgcttcc actcagatca gtcctacacc     1080

gacaccggct tcttagctga atacctctcc tacgactcca gtgacccatg cccggggcag     1140

ttcacgtgcc gcacggggcg gtgtatccgg aaggagctgc gctgtgatgg ctgggccgac     1200

tgcaccgacc acagcgatga gctcaactgc agttgcgacg ccggccacca gttcacgtgc     1260

aagaacaagt tctgcaagcc cctcttctgg gtctgcgaca gtgtgaacga ctgcggagac     1320

aacagcgacg agcaggggtg cagttgtccg gcccagacct tcaggtgttc caatgggaag     1380

tgcctctcga aaagccagca gtgcaatggg aaggacgact gtggggacgg ctccgacgag     1440

gcctcctgcc ccaaggtgaa cgtcgtcact tgtaccaaac acacctaccg ctgcctcaat     1500

gggctctgct tgagcaaggg caaccctgag tgtgacggga aggaggactg tagcgacggc     1560

tcagatgaga aggactgcga ctgtgggctg cggtcattca cgagacaggc tcgtgttgtt     1620

gggggcacgg atgcggatga gggcgagtgg ccctggcagg taagcctgca tgctctgggc     1680

cagggccaca tctgcggtgc ttccctcatc tctcccaact ggctggtctc tgccgcacac     1740

tgctacatcg atgacagagg attcaggtac tcagacccca cgcagtggac ggccttcctg     1800

ggcttgcacg accagagcca gcgcagcgcc cctggggtgc aggagcgcag gctcaagcgc     1860

atcatctccc accccttctt caatgacttc accttcgact atgacatcgc gctgctggag     1920

ctggagaaac cggcagagta cagctccatg gtgcggccca tctgcctgcc ggacgcctcc     1980

catgtcttcc ctgccggcaa ggccatctgg gtcacgggct ggggacacac ccagtatgga     2040

ggcactggcg cgctgatcct gcaaaagggt gagatccgcg tcatcaacca gaccacctgc     2100

gagaacctcc tgccgcagca gatcacgccg cgcatgatgt gcgtgggctt cctcagcggc     2160

ggcgtggact cctgccaggg tgattccggg ggacccctgt ccagcgtgga ggcggatggg     2220

cggatcttcc aggccggtgt ggtgagctgg ggagacggct gcgctcagag gaacaagcca     2280

ggcgtgtaca caaggctccc tctgtttcgg gactggatca aagagaacac tggggta        2337


<210>  6171
<211>  657
<212>  DNA
<213>  Homo Sapiens

<400>  6171
ctggtccaag gctctttgcg tgcagaagag ctttccatcc aggtgtcatg cagaattatg       60

gggatcaccc ttgtgagcaa aaaggcgaac cagcagctga atttcacaga agctaaggag      120

gcctgtaggc tgctgggact aagtttggcc ggcaaggacc aagttgaaac agccttgaaa      180

gctagctttg aaacttgcag ctatggctgg gttggagatg gattcgtggt catctctagg      240

attagcccaa accccaagtg tgggaaaaat ggggtgggtg tcctgattag gaaggttcca      300

gtgagccgac agtttgcagc ctattgttac aactcatctg atacttggac taactcgtgc      360

attccagaaa ttatcaccac caaagatccc atattcaaca ctcaaactgc aacacaaaca      420

acagaattta ttgtcagtga cagtacctac tcggtggcat ccccttactc tacaatacct      480

gcccctacta ctactcctcc tgctccagct tccacttcta ttccacggag aaaaaaattg      540

atttgtgtca cagaagtttt tatggaaact agcaccatgt ctacagaaac tgaaccattt      600

gttgaaaata aagcagcatt caagaatgaa gctgctgggt ttggaggtgt ccccacg         657


<210>  6172
<211>  1359
<212>  DNA
<213>  Homo Sapiens

<400>  6172
gccccggagc tggcccccgc gcccttcacg ctgcccctcc gggtggccgc ggccacgaac       60

cgcgtagttg cgcccacccc gggacccggg acccctgccg agcgccacgc cgacggcttg      120

gcgctcgccc tggagcctgc cctggcgtcc cccgcgggcg ccgccaactt cttggccatg      180

gtagacaacc tgcaggggga ctctggccgc ggctactacc tggagatgct gatcgggacc      240

cccccgcaga agctacagat tctcgttgac actggaagca gtaactttgc cgtggcagga      300

accccgcact cctacataga cacgtacttt gacacagaga ggtctagcac ataccgctcc      360

aagggctttg acgtcacagt gaagtacaca caaggaagct ggacgggctt cgttggggaa      420

gacctcgtca ccatccccaa aggcttcaat acttcttttc ttgtcaacat tgccactatt      480

tttgaatcag agaatttctt tttgcctggg attaaatgga atggaatact tggcctagct      540

tatgccacac ttgccaagcc atcaagttct ctggagacct tcttcgactc cctggtgaca      600

caagcaaaca tccccaacgt tttctccatg cagatgtgtg gagccggctt gcccgttgct      660

ggatctggga ccaacggagg tagtcttgtc ttgggtggaa ttgaaccaag tttgtataaa      720

ggagacatct ggtatacccc tattaaggaa gagtggtact accagataga aattctgaaa      780

ttggaaattg gaggccaaag ccttaatctg gactgcagag agtataacgc agacaaggcc      840

atcgtggaca gtggcaccac gctgctgcgc ctgccccaga aggtgtttga tgcggtggtg      900

gaagctgtgg cccgcgcatc tctgattcca gaattctctg atggtttctg gactgggtcc      960

cagctggcgt gctggacgaa ttcggaaaca ccttggtctt acttccctaa aatctccatc     1020

tacctgagag atgagaactc cagcaggtca ttccgtatca caatcctgcc tcagctttac     1080

attcagccca tgatgggggc cggcctgaat tatgaatgtt accgattcgg catttcccca     1140

tccacaaatg cgctggtgat cggtgccacg gtgatggagg gcttctacgt catcttcgac     1200

agagcccaga agagggtggg cttcgcagcg agcccctgtg cagaaattgc aggtgctgca     1260

gtgtctgaaa tttccgggcc tttctcaaca gaggatgtag ccagcaactg tgtccccgct     1320

cagtctttga gcgagcccat tttgtggatt gtgtcctat                            1359


<210>  6173
<211>  1518
<212>  DNA
<213>  Homo Sapiens

<400>  6173
gatgtgaagg ctcggagctg cggagaggtc cgccaggcgt acggtgccaa gggattcagc       60

ctggcggaca tcccctacca ggagatcgca ggggaacact taagaatctg tcctcaggaa      120

tatacatgct gcaccacaga aatggaagac aagttaagcc aacaaagcaa actcgaattt      180

gaaaaccttg tggaagagac aagccatttt gtgcgcacca cttttgtgtc caggcataag      240

aaatttgacg aatttttccg agagctcctg gagaatgcag aaaagtcact aaatgatatg      300

tttgtacgga cctatggcat gctgtacatg cagaattcag aagtcttcca ggacctcttc      360

acagagctga aaaggtacta cactgggggt aatgtgaatc tggaggaaat gctcaatgac      420

ttttgggctc ggctcctgga acggatgttt cagctgataa accctcagta tcacttcagt      480

gaagactacc tggaatgtgt gagcaaatac actgaccagc tcaagccatt tggagacgtg      540

ccccggaaac tgaagattca ggttacccgc gccttcattg ctgccaggac ctttgtccag      600

gggctgactg tgggcagaga agttgcaaac cgagtttcca aggtcagccc aaccccaggg      660

tgtatccgtg ccctcatgaa gatgctgtac tgcccatact gtcgggggct tcccactgtg      720

aggccctgca acaactactg tctcaacgtc atgaagggct gcttggcaaa tcaggctgac      780

ctcgacacag agtggaatct gtttatagat gcaatgctct tggtggcaga gcgactggag      840

gggccattca acattgagtc ggtcatggac ccgatagatg tcaagatttc tgaagccatt      900

atgaacatgc aagaaaacag catgcaggtg tctgcaaagg tctttcaggg atgtggtcag      960

cccaaacctg ctccagccct cagatctgcc cgctcagctc ctgaaaattt taatacacgt     1020

ttcaggccct acaatcctga ggaaagacca acaactgctg caggcacaag cttggaccgg     1080

ctggtcacag acataaaaga gaaattgaag ctctctaaaa aggtctggtc agcattaccc     1140

tacactatct gcaaggacga gagcgtgaca gcgggcacgt ccaacgagga ggaatgctgg     1200

aacgggcaca gcaaagccag atacttgcct gagatcatga atgatgggct caccaaccag     1260

atcaacaatc ccgaggtgga tgtggacatc actcggcctg acactttcat cagacagcag     1320

attatggctc tccgtgtgat gaccaacaaa ctaaaaaacg cctacaatgg caatgatgtc     1380

aatttccagg acacaagtga tgaatccagt ggctcaggga gtggcagtgg gtgcatggat     1440

gacgtgtgtc ccacggagtt tgagtttgtc accacagagg cccccgcagt ggatcccgac     1500

cggagagagg tggactct                                                   1518


<210>  6174
<211>  1284
<212>  DNA
<213>  Homo Sapiens

<400>  6174
gatgttgcta aagcaatcat caacctagct gtttatggta aagcccagaa cagatcctat       60

gagcgattgg cacttctggt tgatactgtt ggacccagac tgagtggctc caagaaccta      120

gaaaaagcca tccaaattat gtaccaaaac ctgcagcaag atgggctgga gaaagttcac      180

ctggagccag tgagaatacc ccactgggag aggggagaag aatcagctgt gatgctggag      240

ccaagaattc ataagatagc catcctgggt cttggcagca gcattgggac tcctccagaa      300

ggcattacag cagaagttct ggtggtgacc tctttcgatg aactgcagag aagggcctca      360

gaagcaagag ggaagattgt tgtttataac caaccttaca tcaactactc aaggacggtg      420

caataccgaa cgcagggggc ggtggaagct gccaaggttg gggctttggc atctctcatt      480

cgatccgtgg cctccttctc catctacagt cctcacacag gtattcagga ataccaggat      540

ggcgtgccca agattccaac agcctgtatt acggtggaag atgcagaaat gatgtcaaga      600

atggcttctc atgggatcaa aattgtcatt cagctaaaga tgggggcaaa gacctaccca      660

gatactgatt ccttcaacac tgtagcagag atcactggga gcaaatatcc agaacaggtt      720

gtactggtca gtggacatct ggacagctgg gatgttgggc agggtgccat ggatgatggc      780

ggtggagcct ttatatcatg ggaagcactc tcacttatta aagatcttgg gctgcgtcca      840

aagaggactc tgcggctggt gctctggact gcagaagaac aaggtggagt tggtgccttc      900

cagtattatc agttacacaa ggtaaatatt tccaactaca gtctggtgat ggagtctgac      960

gcaggaacct tcttacccac tgggctgcaa ttcactggca gtgaaaaggc cagggccatc     1020

atggaggagg ttatgagcct gctgcagccc ctcaatatca ctcaggtcct gagccatgga     1080

gaagggacag acatcaactt ttggatccaa gctggagtgc ctggagccag tctacttgat     1140

gacttataca agtatttctt cttccatcac tcccacggag acaccatgac tgtcatggat     1200

ccaaagcaga tgaatgttgc tgctgctgtt tgggctgttg tttcttatgt tgttgcagac     1260

atggaagaaa tgctgcctag gtcc                                            1284


<210>  6175
<211>  597
<212>  DNA
<213>  Homo Sapiens

<400>  6175
cagagacaaa agaaagagga gagcaccgaa gaagtgaaaa tagaagtttt gcatcgtcca       60

gaaaactgct ctaagacaag caagaaggga gacctactaa atgcccatta tgacggctac      120

ctggctaaag acggctcgaa attctactgc agccggacac aaaatgaagg ccaccccaaa      180

tggtttgttc ttggtgttgg gcaagtcata aaaggcctag acattgctat gacagatatg      240

tgccctggag aaaagcgaaa agtagttata cccccttcat ttgcatacgg aaaggaaggc      300

tatgcagaag gcaagattcc accggatgct acattgattt ttgagattga actttatgct      360

gtgaccaaag gaccacggag cattgagaca tttaaacaaa tagacatgga caatgacagg      420

cagctctcta aagccgagat aaacctctac ttgcaaaggg aatttgaaaa agatgagaag      480

ccacgtgaca agtcatatca ggatgcagtt ttagaagata tttttaagaa gaatgaccat      540

gatggtgatg gcttcatttc tcccaaggaa tacaatgtat accaacacga tgaacta         597


<210>  6176
<211>  381
<212>  DNA
<213>  Homo Sapiens

<400>  6176
acactcctgc gctcatacat gcagagcgtg tggaccgaag agtctcaatg caccttgctg       60

aatgcgtcca tcacggaaac atttaactgc tccttcagct gtggtccaga ctgctggaaa      120

ctttctcagt acccctgcct ccaggtgtac gttaacctga cttcttccgg ggaaaagctc      180

ctcctctacc acacagaaga gacaataaaa atcaatcaga agtgctccta tatacctaaa      240

tgtggaaaaa attttgaaga atccatgtcc ctggtgaatg ttgtcatgga aaacttcagg      300

aagtatcaac acttctcctg ctattctgac ccagaaggaa accagaagag tgttatccta      360

accaaactct acagttccaa c                                                381


<210>  6177
<211>  186
<212>  DNA
<213>  Homo Sapiens

<400>  6177
acctcctgcg tggggttctt tatgccttac tggctctggg gatcacagct gggcaagcct       60

gtgtccttcg gtaccttccg gaggtgctca tatcctgtgc atgatgagag tcggcagatg      120

atggtgatgg tggaggaatg tgggcgctat gcctccttcc agggcatccc cagcgcagaa      180

tggagg                                                                 186


<210>  6178
<211>  942
<212>  DNA
<213>  Homo Sapiens

<400>  6178
gagacaaact tggaacagct ctgggtagaa gtgggcagcc gggtgagcca ggagctgcat       60

tacaccaagg agaagctggg ggaggaggct gcatacacct ctcagatgct gatacagacc      120

gcacgccagg agggagagaa catcctcaca cccgaagcac ttggcctcca cctccaggca      180

gccctcactg ccagtaaagt ccaagtatca ctctatggga agtcctggga tttgaacaaa      240

atctgctaca agtcaggagt tccccttatt gaaaatggaa tgattgagcg gatgattgag      300

aagctgtttc cgtgcgtgat cctcaccccc ctcgactgct tctgggaggg agccaaactc      360

caagggggct ccgcctacct gcccggccgc ccggatatcc agtggaccaa cctggatcca      420

gagcagctgc tggaggagct gggtcccttt gcctcccttg agggcttccg ggagctgcta      480

gacaaggcac aggtgggcca ggcctacgtg gggcggccct gtctgcaccc tgatgacctc      540

cactgcccac ctagtgcccc caaccatcac agcaggcagg ctcccaatgt ggctcacgag      600

ctgagtgggg gctgccatgg cttctcccac aaattcatgc actggcagga ggaattgctg      660

ctgggaggca tggccagaga cccccaagga gagctgctga gggcagaggc cctgcagagc      720

accttcttgc tgatgagtcc ccgccagctg tacgagcatt tccggggtga ctatcagaca      780

catgacattg gctggagtga ggagcaggcc agcacagtgc tacaagcctg gcagcggcgc      840

tttgtgcagc tggcccagga ggccctgcct gagaacgctt cccagcagat ccatgccttc      900

tcctccacca ccctggatga catcctgcat gcgttctctg aa                         942


<210>  6179
<211>  843
<212>  DNA
<213>  Homo Sapiens

<400>  6179
ggggtggaag tgagtgctgg gtcacccccc atccgcaacg tcactgtggc ctacaagttc       60

cacatggggc tctatggtga gactgggcgg cttttcactg agagctgcag catctctccc      120

aagctccgct ccatcgctgt ctactatgac aacccccaca tggtgccccc tgataagtgc      180

cgatgtgccg tgggcagcat cctgagtgaa ggtgaggaat cgccctcccc tgagctcatc      240

gacctctacc agaaatttgg cttcaaggtg ttctccttcc cggcacccag ccatgtggtg      300

acagccacct tcccctacac caccattctg tccatctggc tggctacccg ccgtgtccat      360

cctgccttgg acacctacat caaggagcgg aagctgtgtg cctatcctcg gctggagatc      420

taccaggaag accagatcca tttcatgtgc ccactggcac ggcagggaga cttctatgtg      480

cctgagatga aggagacaga gtggaaatgg cgggggcttg tggaggccat tgacacccag      540

gtggatggca caggagctga cacaatgagt gacacgagtt ctgtaagctt ggaagtgagc      600

cctggcagcc gggagacttc agctgccaca ctgtcacctg gggcgagcag ccgtggctgg      660

gatgacggtg acacccgcag cgagcacagc tacagcgagt caggtgccag cggctcctct      720

tttgaggagc tggacttgga gggcgagggg cccttagggg agtcacggct ggaccctggg      780

actgagcccc tggggactac caagtggctc tgggagccca ctgcccctga gaagggcaag      840

gag                                                                    843


<210>  6180
<211>  336
<212>  DNA
<213>  Homo Sapiens

<400>  6180
tttttcatac tctgtgaaaa caaatcagtt gccggactaa ccatgaccta tgatggaaat       60

aatccagtga catctcatag agatgtacca ctttcttatt gcaactcaga ctgcaattgt      120

gatgaaagtc aatgggaacc agtctgtgga aacaatggaa taacttacat ctcaccctgt      180

ctagcaggtt gcaaatcttc aagtggcaat aaaaagccta tagtgtttta caactgcagt      240

tgtttggaag taactggtct ccagaacaga aattactcag cccatttggg tgaatgccca      300

agagatgatg cttgtacaag gaaattttac tttttt                                336


<210>  6181
<211>  741
<212>  DNA
<213>  Homo Sapiens

<400>  6181
atcgtgggtg gagaggacgc cgaactcggg cgttggccgt ggcaggggag cctgcgcctg       60

tgggattccc acgtatgcgg agtgagcctg ctcagccacc gctgggcact cacggcggcg      120

cactgctttg aaacctatag tgaccttagt gatccctccg ggtggatggt ccagtttggc      180

cagctgactt ccatgccatc cttctggagc ctgcaggcct actacacccg ttacttcgta      240

tcgaatatct atctgagccc tcgctacctg gggaattcac cctatgacat tgccttggtg      300

aagctgtctg cacctgtcac ctacactaaa cacatccagc ccatctgtct ccaggcctcc      360

acatttgagt ttgagaaccg gacagactgc tgggtgactg gctgggggta catcaaagag      420

gatgaggcac tgccatctcc ccacaccctc caggaagttc aggtcgccat cataaacaac      480

tctatgtgca accacctctt cctcaagtac agtttccgca aggacatctt tggagacatg      540

gtttgtgctg gcaatgccca aggcgggaag gatgcctgct tcggtgactc aggtggaccc      600

ttggcctgta acaagaatgg actgtggtat cagattggag tcgtgagctg gggagtgggc      660

tgtggtcggc ccaatcggcc cggtgtctac accaatatca gccaccactt tgagtggatc      720

cagaagctga tggcccagag t                                                741


<210>  6182
<211>  1824
<212>  DNA
<213>  Homo Sapiens

<400>  6182
atggaaagat ttcgtctgga gaagaagtta cctggtcctg atgaagaagc tgttgtggat       60

cttggcaaaa ctagctcaac tgtgaacacc aagtttgaaa aagaagaact agaaagtcat      120

agagctgtat atattggtgt tcacgtcccg tttagtaaag agagtcgtcg gcgtcatagg      180

catcgcggac acaaacatca ccaccggaga agaaaagata aagaatcaga taaagaagat      240

ggacgggaat ctccttctta tgatacacca tcccagagag ttcagtttat ccttggtact      300

gaagatgatg atgaagaaca tattccccat gatctcttca cggaaatgga tgaactgtgt      360

tacagagatg gagaagaata tgaatggaaa gaaactgcta gatggctgaa atttgaagag      420

gatgttgaag atggcggtga ccgatggagt aaaccttatg tggcaactct ctctttgcac      480

agtctttttg aactaaggag ttgcatcctc aatggaacag tcatgctgga tatgagagca      540

agcactctag atgaaatagc agatatggta ttagacaaca tgatagcttc tggccaatta      600

gacgagtcca tacgagagaa tgtcagagaa gctcttctga agagacatca tcatcagaat      660

gagaaaagat tcaccagtcg gattcctctt gttcgatctt ttgcagatat aggcaagaaa      720

cattctgacc ctcacttgct tgaaaggaat ggggaaggcc tttcagcctc ccgccactct      780

ttgcgaacag gtctgtctgc ctcaaacctt tccttgagag gagaatcacc tttatctctt      840

cttcttggtc atcttcttcc ttcttcaaga gctggaaccc ctgcaggctc aaggtgtaca      900

accccagtac ccacccctca aaacagtcct ccttctagcc ctagcatcag ccgcctgacc      960

tccagaagtt cccaagagag tcagcgtcag gccccagaac tactggtttc acctgccagt     1020

gatgatattc ccacagtagt aattcatccg cctgaggaag acttagaagc agcgctgaaa     1080

ggcgaggagc agaagaatga ggaaaatgtt gacttaactc caggtatttt ggcctctccc     1140

cagtctgctc ctggaaactt ggacaatagt aaaagtggag aaattaaagg taatggaagt     1200

ggtggaagca gagaaaatag tactgttgac ttcagcaagg ttgatatgaa tttcatgaga     1260

aaaattccta cgggtgctga ggcatccaac gtcctggtgg gcgaagtaga ctttttggaa     1320

aggccaataa ttgcatttgt gagactggct cctgctgtcc tccttacagg gttgactgag     1380

gtccctgttc caaccaggtt tttgtttttg ttattgggtc cagcgggcaa ggcaccacag     1440

taccatgaaa ttggacgatc aatagccact ctcatgacag atgagatttt ccatgatgta     1500

gcttataaag caaaagacag aaatgacctc ttatctggaa ttgatgaatt tttagatcaa     1560

gtaactgtcc tacctccagg agagtgggat ccttctatac gcatagaacc accaaaaagt     1620

gtcccttctc aggaaaagag aaagattcct gtgtttcaca atggatctac ccccacactg     1680

ggtgagactc ctaaagaggc cgctcatcat gctgggcctg agctacagag gactggacgg     1740

ctttttggtg gtttgatact tgacatcaaa aggaaagcac cttttttctt gagtgacttc     1800

aaggatgcat taagcctgca gtgc                                            1824


<210>  6183
<211>  621
<212>  DNA
<213>  Homo Sapiens

<400>  6183
gacggcagcg agccggcggc cggggcgggg cggggcggag cccgcgccgt gcgggtggac       60

gtgagactgc cgcgccagga cgctctggtc ctggagggcg tcaggatcgg ctccgaagcc      120

gacccggcgc ccctgctggg cggtcgtctg ctgctgatgg acatcgtgga tgccgagcag      180

gaggcaccag tggaaggctg gattgcagtg gcatacgtgg gcaaggagca ggcggcccag      240

ttccaccagg agaataaggg cagtggcccg caggcctatc ccaaggccct ggtccagcag      300

atgcggcggg ccctcttcct gggtgcctct gccctgcttc ttctcatcct gaaccacaac      360

gtggtccgag agctggacat atcccagctt ctgctcaggc cagtgatcgt cctccattat      420

tcctccaatg tcaccaagct gttggatgca ttgctgcaga ggacccaggc cacggctgag      480

atcaccagcg gagagtccct gtctgccaat atcgagtgga agttgacctt gtggaccacc      540

tgtggcctct ccaaggatgg ctatggagga tggcaggact tggtctgcct tggaggcagt      600

cgtgcccagg agcagaaacc c                                                621


<210>  6184
<211>  1176
<212>  DNA
<213>  Homo Sapiens

<400>  6184
tttagaagtg actcttcctc tagtttgcca cctaagttac tactagtatc ctttgatggc       60

ttcagagctg attatctgaa gaactatgaa tttcctcatc tccagaattt tatcaaagaa      120

ggtgttttgg tagagcatgt taaaaatgtt tttatcacaa aaacatttcc aaaccactac      180

agtattgtga caggcttgta tgaagaaagc catggcattg tggctaattc catgtatgat      240

gcagtcacaa agaaacactt ttctgactct aatgacaagg atcctttttg gtggaatgag      300

gcagtaccta tttgggtgac caatcagctt caggaaaaca gatcaagtgc tgctgctatg      360

tggcctggta ctgatgtacc cattcacgat accatctctt cctattttat gaattacaac      420

tcctcagtgt catttgagga aagactaaat aatattacta tgtggctaaa caattcgaac      480

ccaccagtca cctttgcaac actatattgg gaagaaccag atgcaagtgg ccacaaatac      540

ggacctgaag ataaagaaaa catgagcaga gtgttgaaaa aaatagatga tcttatcggt      600

gacttagtcc aaagactcaa gatgttaggg ctatgggaaa atcttaatgt gatcattaca      660

agtgatcatg ggatgaccca gtgttctcag gacagactga taaacctgga ttcctgcatc      720

gatcattcat actacactct tatagatttg agcccagttg ctgcaatact tcccaaaata      780

aatagaacag aggtttataa caaactgaaa aactgtagcc ctcatatgaa tgtttatctc      840

aaagaagaca ttcctaacag attttattac caacataatg atcgaattca gcccattatt      900

ttggttgccg atgaaggctg gacaattgtg ctaaatgaat catcacaaaa attaggtgac      960

catggttatg ataattcttt gcctagtatg catccatttc tagctgccca cggacctgca     1020

tttcacaaag gctacaagca tagcacaatt aacattgtgg atatttatcc aatgatgtgc     1080

cacatcctgg gattaaaacc acatcccaat aatgggacct ttggtcatac taagtgcttg     1140

ttagttgacc agtggtgcat taatctccca gaagcc                               1176


<210>  6185
<211>  426
<212>  DNA
<213>  Homo Sapiens

<400>  6185
cagaagcagt attgggtctg caactcatcc gatgcaagta tttcatacac ctactgtgat       60

aaaatgcaat acccaatttc aattaatgtt aacccctgta tagaattgaa aggatccaaa      120

ggattattgc acattttcta cattccaagg agagatttaa agcaattata tttcaatctc      180

tatataactg tcaacaccat gaatcttcca aagcgcaaag aagttatttg ccgaggatct      240

gatgacgatt actctttttg cagagctctg aagggagaga ctgtgaatac aacaatatca      300

ttctccttca agggaataaa attttctaag ggaaaataca aatgtgttgt tgaagctatt      360

tctgggagcc cagaagaaat gctcttttgc ttggagtttg tcatcctaca ccaacctaat      420

tcaaat                                                                 426


<210>  6186
<211>  23
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized

<400>  6186
ctgttattgc tagcgtttta gca                                               23


<210>  6187
<211>  18
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized

<400>  6187
gccaccagaa gcggccgc                                                     18


<210>  6188
<211>  50
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized

<400>  6188
ttgttaatat acctctatac tttaacgtca aggagaaaaa accccggatc                  50


<210>  6189
<211>  64
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized


<220>
<221>  misc_feature
<222>  (25)..(39)
<223>  any nucleotide

<400>  6189
ctgcatcctt tagtgagggt tgaannnnnn nnnnnnnnnt tcgatccggg gttttttctc       60

cttg                                                                    64


<210>  6190
<211>  59
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized

<400>  6190
ttcaaccctc actaaaggat gcagttactt cgctgttttt caatattttc tgttattgc        59


<210>  6191
<211>  42
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized

<400>  6191
tgctaaaacg ctagcaataa cagaaaatat tgaaaaacag cg                          42


<210>  6192
<211>  62
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized


<220>
<221>  misc_feature
<222>  (34)..(43)
<223>  any nucleotide

<400>  6192
tcgtcggcag cgtcagatgt gtataagaga cagnnnnnnn nnngagaaaa aaccccggat       60

cg                                                                      62


<210>  6193
<211>  69
<212>  DNA
<213>  Artificial Sequence

<220>
<223>  chemically synthesized


<220>
<221>  misc_feature
<222>  (35)..(44)
<223>  any nucleotide

<400>  6193
gtctcgtggg ctcggagatg tgtataagag acagnnnnnn nnnnacgcta gcaataacag       60

aaaatattg                                                               69


